data_8RG3
# 
_entry.id   8RG3 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.400 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8RG3         pdb_00008rg3 10.2210/pdb8rg3/pdb 
WWPDB D_1292134778 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-01 
2 'Structure model' 1 1 2025-01-08 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_CSD'          
4  2 'Structure model' '_citation.journal_id_ISSN'         
5  2 'Structure model' '_citation.journal_volume'          
6  2 'Structure model' '_citation.page_first'              
7  2 'Structure model' '_citation.page_last'               
8  2 'Structure model' '_citation.pdbx_database_id_DOI'    
9  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
10 2 'Structure model' '_citation.title'                   
11 2 'Structure model' '_citation.year'                    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8RG3 
_pdbx_database_status.recvd_initial_deposition_date   2023-12-13 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              beatriz.trastoy@gmail.com 
_pdbx_contact_author.name_first         Beatriz 
_pdbx_contact_author.name_last          Trastoy 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-2178-732X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Perez-Curz, C.'       1  0000-0003-2796-5315 
'Moraleda-Montoya, A.' 2  0000-0003-4502-5976 
'Liebana, R.'          3  0000-0002-2196-5632 
'Lorizate, M.'         4  0000-0001-8173-2788 
'Arrizabalaga, U.'     5  ?                   
'Garcia-Alija, M.'     6  0000-0002-8805-1325 
'Terrones, O.'         7  0000-0001-7421-6486 
'Contreras, F.X.'      8  0000-0003-0875-634X 
'Guerin, M.E.'         9  0000-0001-9524-3184 
'Trastoy, B.'          10 0000-0002-2178-732X 
'Alonso-Saez, L.'      11 0000-0003-1757-4767 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                10906 
_citation.page_last                 10906 
_citation.title                     'Mechanisms of recalcitrant fucoidan breakdown in marine Planctomycetota.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-55268-w 
_citation.pdbx_database_id_PubMed   39738071 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Perez-Cruz, C.'        1  ?                   
primary 'Moraleda-Montoya, A.'  2  ?                   
primary 'Liebana, R.'           3  ?                   
primary 'Terrones, O.'          4  ?                   
primary 'Arrizabalaga, U.'      5  ?                   
primary 'Garcia-Alija, M.'      6  ?                   
primary 'Lorizate, M.'          7  ?                   
primary 'Martinez Gascuena, A.' 8  ?                   
primary 'Garcia-Alvarez, I.'    9  0000-0002-2273-5046 
primary 'Nieto-Garai, J.A.'     10 0000-0002-8665-099X 
primary 'Olazar-Intxausti, J.'  11 ?                   
primary 'Rodriguez-Colinas, B.' 12 ?                   
primary 'Mann, E.'              13 ?                   
primary 'Chiara, J.L.'          14 0000-0002-8153-1852 
primary 'Contreras, F.X.'       15 0000-0003-0875-634X 
primary 'Guerin, M.E.'          16 0000-0001-9524-3184 
primary 'Trastoy, B.'           17 0000-0002-2178-732X 
primary 'Alonso-Saez, L.'       18 0000-0003-1757-4767 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Glycoside-hydrolase family GH114 TIM-barrel domain-containing protein' 43353.996 6   ? ? ? ? 
2 non-polymer syn 1,2-ETHANEDIOL                                                          62.068    3   ? ? ? ? 
3 water       nat water                                                                   18.015    166 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MHHHHHHENLYFQGSGDESHYPEFSWDTVPIAFHFGKSQGLLTKEEAEFVATRSNFICLEKGHATRTHGTTEAGIEAEAR
QLKNLNPKMKVIFYWNTFLDYSMFAAHKEYAKHPQWWLRTTTGELDRKKGQLMRYDLSNAEFRNWWTNVAAKAVVDGTCD
GVFMDAFPQIASQANRKLWGDEKFEAIQQGLQDIIQETRQKIGDDKLIVYNGIRSTPDWSAGFDFAEYTDAAMIEHFGHF
QSASKETMLRDILEMQRAAKAGKIVVLKGWAGFTFIDDQAMRKPLTQKRRVAKDSLKFPLACFLAGAQENCYFIYNWGYR
MENGCLEWYPEFDKPLGKPVGEMVRDGWKLSREYKHASVRVDLESKEAEIRWR
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MHHHHHHENLYFQGSGDESHYPEFSWDTVPIAFHFGKSQGLLTKEEAEFVATRSNFICLEKGHATRTHGTTEAGIEAEAR
QLKNLNPKMKVIFYWNTFLDYSMFAAHKEYAKHPQWWLRTTTGELDRKKGQLMRYDLSNAEFRNWWTNVAAKAVVDGTCD
GVFMDAFPQIASQANRKLWGDEKFEAIQQGLQDIIQETRQKIGDDKLIVYNGIRSTPDWSAGFDFAEYTDAAMIEHFGHF
QSASKETMLRDILEMQRAAKAGKIVVLKGWAGFTFIDDQAMRKPLTQKRRVAKDSLKFPLACFLAGAQENCYFIYNWGYR
MENGCLEWYPEFDKPLGKPVGEMVRDGWKLSREYKHASVRVDLESKEAEIRWR
;
_entity_poly.pdbx_strand_id                 A,B,C,D,E,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 1,2-ETHANEDIOL EDO 
3 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   HIS n 
1 3   HIS n 
1 4   HIS n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   GLU n 
1 9   ASN n 
1 10  LEU n 
1 11  TYR n 
1 12  PHE n 
1 13  GLN n 
1 14  GLY n 
1 15  SER n 
1 16  GLY n 
1 17  ASP n 
1 18  GLU n 
1 19  SER n 
1 20  HIS n 
1 21  TYR n 
1 22  PRO n 
1 23  GLU n 
1 24  PHE n 
1 25  SER n 
1 26  TRP n 
1 27  ASP n 
1 28  THR n 
1 29  VAL n 
1 30  PRO n 
1 31  ILE n 
1 32  ALA n 
1 33  PHE n 
1 34  HIS n 
1 35  PHE n 
1 36  GLY n 
1 37  LYS n 
1 38  SER n 
1 39  GLN n 
1 40  GLY n 
1 41  LEU n 
1 42  LEU n 
1 43  THR n 
1 44  LYS n 
1 45  GLU n 
1 46  GLU n 
1 47  ALA n 
1 48  GLU n 
1 49  PHE n 
1 50  VAL n 
1 51  ALA n 
1 52  THR n 
1 53  ARG n 
1 54  SER n 
1 55  ASN n 
1 56  PHE n 
1 57  ILE n 
1 58  CYS n 
1 59  LEU n 
1 60  GLU n 
1 61  LYS n 
1 62  GLY n 
1 63  HIS n 
1 64  ALA n 
1 65  THR n 
1 66  ARG n 
1 67  THR n 
1 68  HIS n 
1 69  GLY n 
1 70  THR n 
1 71  THR n 
1 72  GLU n 
1 73  ALA n 
1 74  GLY n 
1 75  ILE n 
1 76  GLU n 
1 77  ALA n 
1 78  GLU n 
1 79  ALA n 
1 80  ARG n 
1 81  GLN n 
1 82  LEU n 
1 83  LYS n 
1 84  ASN n 
1 85  LEU n 
1 86  ASN n 
1 87  PRO n 
1 88  LYS n 
1 89  MET n 
1 90  LYS n 
1 91  VAL n 
1 92  ILE n 
1 93  PHE n 
1 94  TYR n 
1 95  TRP n 
1 96  ASN n 
1 97  THR n 
1 98  PHE n 
1 99  LEU n 
1 100 ASP n 
1 101 TYR n 
1 102 SER n 
1 103 MET n 
1 104 PHE n 
1 105 ALA n 
1 106 ALA n 
1 107 HIS n 
1 108 LYS n 
1 109 GLU n 
1 110 TYR n 
1 111 ALA n 
1 112 LYS n 
1 113 HIS n 
1 114 PRO n 
1 115 GLN n 
1 116 TRP n 
1 117 TRP n 
1 118 LEU n 
1 119 ARG n 
1 120 THR n 
1 121 THR n 
1 122 THR n 
1 123 GLY n 
1 124 GLU n 
1 125 LEU n 
1 126 ASP n 
1 127 ARG n 
1 128 LYS n 
1 129 LYS n 
1 130 GLY n 
1 131 GLN n 
1 132 LEU n 
1 133 MET n 
1 134 ARG n 
1 135 TYR n 
1 136 ASP n 
1 137 LEU n 
1 138 SER n 
1 139 ASN n 
1 140 ALA n 
1 141 GLU n 
1 142 PHE n 
1 143 ARG n 
1 144 ASN n 
1 145 TRP n 
1 146 TRP n 
1 147 THR n 
1 148 ASN n 
1 149 VAL n 
1 150 ALA n 
1 151 ALA n 
1 152 LYS n 
1 153 ALA n 
1 154 VAL n 
1 155 VAL n 
1 156 ASP n 
1 157 GLY n 
1 158 THR n 
1 159 CYS n 
1 160 ASP n 
1 161 GLY n 
1 162 VAL n 
1 163 PHE n 
1 164 MET n 
1 165 ASP n 
1 166 ALA n 
1 167 PHE n 
1 168 PRO n 
1 169 GLN n 
1 170 ILE n 
1 171 ALA n 
1 172 SER n 
1 173 GLN n 
1 174 ALA n 
1 175 ASN n 
1 176 ARG n 
1 177 LYS n 
1 178 LEU n 
1 179 TRP n 
1 180 GLY n 
1 181 ASP n 
1 182 GLU n 
1 183 LYS n 
1 184 PHE n 
1 185 GLU n 
1 186 ALA n 
1 187 ILE n 
1 188 GLN n 
1 189 GLN n 
1 190 GLY n 
1 191 LEU n 
1 192 GLN n 
1 193 ASP n 
1 194 ILE n 
1 195 ILE n 
1 196 GLN n 
1 197 GLU n 
1 198 THR n 
1 199 ARG n 
1 200 GLN n 
1 201 LYS n 
1 202 ILE n 
1 203 GLY n 
1 204 ASP n 
1 205 ASP n 
1 206 LYS n 
1 207 LEU n 
1 208 ILE n 
1 209 VAL n 
1 210 TYR n 
1 211 ASN n 
1 212 GLY n 
1 213 ILE n 
1 214 ARG n 
1 215 SER n 
1 216 THR n 
1 217 PRO n 
1 218 ASP n 
1 219 TRP n 
1 220 SER n 
1 221 ALA n 
1 222 GLY n 
1 223 PHE n 
1 224 ASP n 
1 225 PHE n 
1 226 ALA n 
1 227 GLU n 
1 228 TYR n 
1 229 THR n 
1 230 ASP n 
1 231 ALA n 
1 232 ALA n 
1 233 MET n 
1 234 ILE n 
1 235 GLU n 
1 236 HIS n 
1 237 PHE n 
1 238 GLY n 
1 239 HIS n 
1 240 PHE n 
1 241 GLN n 
1 242 SER n 
1 243 ALA n 
1 244 SER n 
1 245 LYS n 
1 246 GLU n 
1 247 THR n 
1 248 MET n 
1 249 LEU n 
1 250 ARG n 
1 251 ASP n 
1 252 ILE n 
1 253 LEU n 
1 254 GLU n 
1 255 MET n 
1 256 GLN n 
1 257 ARG n 
1 258 ALA n 
1 259 ALA n 
1 260 LYS n 
1 261 ALA n 
1 262 GLY n 
1 263 LYS n 
1 264 ILE n 
1 265 VAL n 
1 266 VAL n 
1 267 LEU n 
1 268 LYS n 
1 269 GLY n 
1 270 TRP n 
1 271 ALA n 
1 272 GLY n 
1 273 PHE n 
1 274 THR n 
1 275 PHE n 
1 276 ILE n 
1 277 ASP n 
1 278 ASP n 
1 279 GLN n 
1 280 ALA n 
1 281 MET n 
1 282 ARG n 
1 283 LYS n 
1 284 PRO n 
1 285 LEU n 
1 286 THR n 
1 287 GLN n 
1 288 LYS n 
1 289 ARG n 
1 290 ARG n 
1 291 VAL n 
1 292 ALA n 
1 293 LYS n 
1 294 ASP n 
1 295 SER n 
1 296 LEU n 
1 297 LYS n 
1 298 PHE n 
1 299 PRO n 
1 300 LEU n 
1 301 ALA n 
1 302 CYS n 
1 303 PHE n 
1 304 LEU n 
1 305 ALA n 
1 306 GLY n 
1 307 ALA n 
1 308 GLN n 
1 309 GLU n 
1 310 ASN n 
1 311 CYS n 
1 312 TYR n 
1 313 PHE n 
1 314 ILE n 
1 315 TYR n 
1 316 ASN n 
1 317 TRP n 
1 318 GLY n 
1 319 TYR n 
1 320 ARG n 
1 321 MET n 
1 322 GLU n 
1 323 ASN n 
1 324 GLY n 
1 325 CYS n 
1 326 LEU n 
1 327 GLU n 
1 328 TRP n 
1 329 TYR n 
1 330 PRO n 
1 331 GLU n 
1 332 PHE n 
1 333 ASP n 
1 334 LYS n 
1 335 PRO n 
1 336 LEU n 
1 337 GLY n 
1 338 LYS n 
1 339 PRO n 
1 340 VAL n 
1 341 GLY n 
1 342 GLU n 
1 343 MET n 
1 344 VAL n 
1 345 ARG n 
1 346 ASP n 
1 347 GLY n 
1 348 TRP n 
1 349 LYS n 
1 350 LEU n 
1 351 SER n 
1 352 ARG n 
1 353 GLU n 
1 354 TYR n 
1 355 LYS n 
1 356 HIS n 
1 357 ALA n 
1 358 SER n 
1 359 VAL n 
1 360 ARG n 
1 361 VAL n 
1 362 ASP n 
1 363 LEU n 
1 364 GLU n 
1 365 SER n 
1 366 LYS n 
1 367 GLU n 
1 368 ALA n 
1 369 GLU n 
1 370 ILE n 
1 371 ARG n 
1 372 TRP n 
1 373 ARG n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   373 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 K239x_02140 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Planctomycetes bacterium K23_9' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1930275 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?                 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ?                 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?                 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ?                 'C3 H7 N O2 S'   121.158 
EDO non-polymer         . 1,2-ETHANEDIOL  'ETHYLENE GLYCOL' 'C2 H6 O2'       62.068  
GLN 'L-peptide linking' y GLUTAMINE       ?                 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ?                 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ?                 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ?                 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ?                 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ?                 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ?                 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ?                 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ?                 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ?                 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ?                 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ?                 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?                 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ?                 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ?                 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   20  ?   ?   ?   A . n 
A 1 2   HIS 2   21  ?   ?   ?   A . n 
A 1 3   HIS 3   22  ?   ?   ?   A . n 
A 1 4   HIS 4   23  ?   ?   ?   A . n 
A 1 5   HIS 5   24  ?   ?   ?   A . n 
A 1 6   HIS 6   25  ?   ?   ?   A . n 
A 1 7   HIS 7   26  ?   ?   ?   A . n 
A 1 8   GLU 8   27  ?   ?   ?   A . n 
A 1 9   ASN 9   28  ?   ?   ?   A . n 
A 1 10  LEU 10  29  ?   ?   ?   A . n 
A 1 11  TYR 11  30  ?   ?   ?   A . n 
A 1 12  PHE 12  31  ?   ?   ?   A . n 
A 1 13  GLN 13  32  ?   ?   ?   A . n 
A 1 14  GLY 14  33  ?   ?   ?   A . n 
A 1 15  SER 15  34  ?   ?   ?   A . n 
A 1 16  GLY 16  35  ?   ?   ?   A . n 
A 1 17  ASP 17  36  ?   ?   ?   A . n 
A 1 18  GLU 18  37  37  GLU GLU A . n 
A 1 19  SER 19  38  38  SER SER A . n 
A 1 20  HIS 20  39  39  HIS HIS A . n 
A 1 21  TYR 21  40  40  TYR TYR A . n 
A 1 22  PRO 22  41  41  PRO PRO A . n 
A 1 23  GLU 23  42  42  GLU GLU A . n 
A 1 24  PHE 24  43  43  PHE PHE A . n 
A 1 25  SER 25  44  44  SER SER A . n 
A 1 26  TRP 26  45  45  TRP TRP A . n 
A 1 27  ASP 27  46  46  ASP ASP A . n 
A 1 28  THR 28  47  47  THR THR A . n 
A 1 29  VAL 29  48  48  VAL VAL A . n 
A 1 30  PRO 30  49  49  PRO PRO A . n 
A 1 31  ILE 31  50  50  ILE ILE A . n 
A 1 32  ALA 32  51  51  ALA ALA A . n 
A 1 33  PHE 33  52  52  PHE PHE A . n 
A 1 34  HIS 34  53  53  HIS HIS A . n 
A 1 35  PHE 35  54  54  PHE PHE A . n 
A 1 36  GLY 36  55  55  GLY GLY A . n 
A 1 37  LYS 37  56  56  LYS LYS A . n 
A 1 38  SER 38  57  57  SER SER A . n 
A 1 39  GLN 39  58  58  GLN GLN A . n 
A 1 40  GLY 40  59  59  GLY GLY A . n 
A 1 41  LEU 41  60  60  LEU LEU A . n 
A 1 42  LEU 42  61  61  LEU LEU A . n 
A 1 43  THR 43  62  62  THR THR A . n 
A 1 44  LYS 44  63  63  LYS LYS A . n 
A 1 45  GLU 45  64  64  GLU GLU A . n 
A 1 46  GLU 46  65  65  GLU GLU A . n 
A 1 47  ALA 47  66  66  ALA ALA A . n 
A 1 48  GLU 48  67  67  GLU GLU A . n 
A 1 49  PHE 49  68  68  PHE PHE A . n 
A 1 50  VAL 50  69  69  VAL VAL A . n 
A 1 51  ALA 51  70  70  ALA ALA A . n 
A 1 52  THR 52  71  71  THR THR A . n 
A 1 53  ARG 53  72  72  ARG ARG A . n 
A 1 54  SER 54  73  73  SER SER A . n 
A 1 55  ASN 55  74  74  ASN ASN A . n 
A 1 56  PHE 56  75  75  PHE PHE A . n 
A 1 57  ILE 57  76  76  ILE ILE A . n 
A 1 58  CYS 58  77  77  CYS CYS A . n 
A 1 59  LEU 59  78  78  LEU LEU A . n 
A 1 60  GLU 60  79  79  GLU GLU A . n 
A 1 61  LYS 61  80  80  LYS LYS A . n 
A 1 62  GLY 62  81  81  GLY GLY A . n 
A 1 63  HIS 63  82  82  HIS HIS A . n 
A 1 64  ALA 64  83  83  ALA ALA A . n 
A 1 65  THR 65  84  84  THR THR A . n 
A 1 66  ARG 66  85  85  ARG ARG A . n 
A 1 67  THR 67  86  86  THR THR A . n 
A 1 68  HIS 68  87  87  HIS HIS A . n 
A 1 69  GLY 69  88  88  GLY GLY A . n 
A 1 70  THR 70  89  89  THR THR A . n 
A 1 71  THR 71  90  90  THR THR A . n 
A 1 72  GLU 72  91  91  GLU GLU A . n 
A 1 73  ALA 73  92  92  ALA ALA A . n 
A 1 74  GLY 74  93  93  GLY GLY A . n 
A 1 75  ILE 75  94  94  ILE ILE A . n 
A 1 76  GLU 76  95  95  GLU GLU A . n 
A 1 77  ALA 77  96  96  ALA ALA A . n 
A 1 78  GLU 78  97  97  GLU GLU A . n 
A 1 79  ALA 79  98  98  ALA ALA A . n 
A 1 80  ARG 80  99  99  ARG ARG A . n 
A 1 81  GLN 81  100 100 GLN GLN A . n 
A 1 82  LEU 82  101 101 LEU LEU A . n 
A 1 83  LYS 83  102 102 LYS LYS A . n 
A 1 84  ASN 84  103 103 ASN ASN A . n 
A 1 85  LEU 85  104 104 LEU LEU A . n 
A 1 86  ASN 86  105 105 ASN ASN A . n 
A 1 87  PRO 87  106 106 PRO PRO A . n 
A 1 88  LYS 88  107 107 LYS LYS A . n 
A 1 89  MET 89  108 108 MET MET A . n 
A 1 90  LYS 90  109 109 LYS LYS A . n 
A 1 91  VAL 91  110 110 VAL VAL A . n 
A 1 92  ILE 92  111 111 ILE ILE A . n 
A 1 93  PHE 93  112 112 PHE PHE A . n 
A 1 94  TYR 94  113 113 TYR TYR A . n 
A 1 95  TRP 95  114 114 TRP TRP A . n 
A 1 96  ASN 96  115 115 ASN ASN A . n 
A 1 97  THR 97  116 116 THR THR A . n 
A 1 98  PHE 98  117 117 PHE PHE A . n 
A 1 99  LEU 99  118 118 LEU LEU A . n 
A 1 100 ASP 100 119 119 ASP ASP A . n 
A 1 101 TYR 101 120 120 TYR TYR A . n 
A 1 102 SER 102 121 121 SER SER A . n 
A 1 103 MET 103 122 122 MET MET A . n 
A 1 104 PHE 104 123 123 PHE PHE A . n 
A 1 105 ALA 105 124 124 ALA ALA A . n 
A 1 106 ALA 106 125 125 ALA ALA A . n 
A 1 107 HIS 107 126 126 HIS HIS A . n 
A 1 108 LYS 108 127 127 LYS LYS A . n 
A 1 109 GLU 109 128 128 GLU GLU A . n 
A 1 110 TYR 110 129 129 TYR TYR A . n 
A 1 111 ALA 111 130 130 ALA ALA A . n 
A 1 112 LYS 112 131 131 LYS LYS A . n 
A 1 113 HIS 113 132 132 HIS HIS A . n 
A 1 114 PRO 114 133 133 PRO PRO A . n 
A 1 115 GLN 115 134 134 GLN GLN A . n 
A 1 116 TRP 116 135 135 TRP TRP A . n 
A 1 117 TRP 117 136 136 TRP TRP A . n 
A 1 118 LEU 118 137 137 LEU LEU A . n 
A 1 119 ARG 119 138 138 ARG ARG A . n 
A 1 120 THR 120 139 139 THR THR A . n 
A 1 121 THR 121 140 140 THR THR A . n 
A 1 122 THR 122 141 141 THR THR A . n 
A 1 123 GLY 123 142 142 GLY GLY A . n 
A 1 124 GLU 124 143 143 GLU GLU A . n 
A 1 125 LEU 125 144 144 LEU LEU A . n 
A 1 126 ASP 126 145 145 ASP ASP A . n 
A 1 127 ARG 127 146 146 ARG ARG A . n 
A 1 128 LYS 128 147 147 LYS LYS A . n 
A 1 129 LYS 129 148 148 LYS LYS A . n 
A 1 130 GLY 130 149 149 GLY GLY A . n 
A 1 131 GLN 131 150 150 GLN GLN A . n 
A 1 132 LEU 132 151 151 LEU LEU A . n 
A 1 133 MET 133 152 152 MET MET A . n 
A 1 134 ARG 134 153 153 ARG ARG A . n 
A 1 135 TYR 135 154 154 TYR TYR A . n 
A 1 136 ASP 136 155 155 ASP ASP A . n 
A 1 137 LEU 137 156 156 LEU LEU A . n 
A 1 138 SER 138 157 157 SER SER A . n 
A 1 139 ASN 139 158 158 ASN ASN A . n 
A 1 140 ALA 140 159 159 ALA ALA A . n 
A 1 141 GLU 141 160 160 GLU GLU A . n 
A 1 142 PHE 142 161 161 PHE PHE A . n 
A 1 143 ARG 143 162 162 ARG ARG A . n 
A 1 144 ASN 144 163 163 ASN ASN A . n 
A 1 145 TRP 145 164 164 TRP TRP A . n 
A 1 146 TRP 146 165 165 TRP TRP A . n 
A 1 147 THR 147 166 166 THR THR A . n 
A 1 148 ASN 148 167 167 ASN ASN A . n 
A 1 149 VAL 149 168 168 VAL VAL A . n 
A 1 150 ALA 150 169 169 ALA ALA A . n 
A 1 151 ALA 151 170 170 ALA ALA A . n 
A 1 152 LYS 152 171 171 LYS LYS A . n 
A 1 153 ALA 153 172 172 ALA ALA A . n 
A 1 154 VAL 154 173 173 VAL VAL A . n 
A 1 155 VAL 155 174 174 VAL VAL A . n 
A 1 156 ASP 156 175 175 ASP ASP A . n 
A 1 157 GLY 157 176 176 GLY GLY A . n 
A 1 158 THR 158 177 177 THR THR A . n 
A 1 159 CYS 159 178 178 CYS CYS A . n 
A 1 160 ASP 160 179 179 ASP ASP A . n 
A 1 161 GLY 161 180 180 GLY GLY A . n 
A 1 162 VAL 162 181 181 VAL VAL A . n 
A 1 163 PHE 163 182 182 PHE PHE A . n 
A 1 164 MET 164 183 183 MET MET A . n 
A 1 165 ASP 165 184 184 ASP ASP A . n 
A 1 166 ALA 166 185 185 ALA ALA A . n 
A 1 167 PHE 167 186 186 PHE PHE A . n 
A 1 168 PRO 168 187 187 PRO PRO A . n 
A 1 169 GLN 169 188 188 GLN GLN A . n 
A 1 170 ILE 170 189 189 ILE ILE A . n 
A 1 171 ALA 171 190 190 ALA ALA A . n 
A 1 172 SER 172 191 191 SER SER A . n 
A 1 173 GLN 173 192 192 GLN GLN A . n 
A 1 174 ALA 174 193 193 ALA ALA A . n 
A 1 175 ASN 175 194 194 ASN ASN A . n 
A 1 176 ARG 176 195 195 ARG ARG A . n 
A 1 177 LYS 177 196 196 LYS LYS A . n 
A 1 178 LEU 178 197 197 LEU LEU A . n 
A 1 179 TRP 179 198 198 TRP TRP A . n 
A 1 180 GLY 180 199 199 GLY GLY A . n 
A 1 181 ASP 181 200 200 ASP ASP A . n 
A 1 182 GLU 182 201 201 GLU GLU A . n 
A 1 183 LYS 183 202 202 LYS LYS A . n 
A 1 184 PHE 184 203 203 PHE PHE A . n 
A 1 185 GLU 185 204 204 GLU GLU A . n 
A 1 186 ALA 186 205 205 ALA ALA A . n 
A 1 187 ILE 187 206 206 ILE ILE A . n 
A 1 188 GLN 188 207 207 GLN GLN A . n 
A 1 189 GLN 189 208 208 GLN GLN A . n 
A 1 190 GLY 190 209 209 GLY GLY A . n 
A 1 191 LEU 191 210 210 LEU LEU A . n 
A 1 192 GLN 192 211 211 GLN GLN A . n 
A 1 193 ASP 193 212 212 ASP ASP A . n 
A 1 194 ILE 194 213 213 ILE ILE A . n 
A 1 195 ILE 195 214 214 ILE ILE A . n 
A 1 196 GLN 196 215 215 GLN GLN A . n 
A 1 197 GLU 197 216 216 GLU GLU A . n 
A 1 198 THR 198 217 217 THR THR A . n 
A 1 199 ARG 199 218 218 ARG ARG A . n 
A 1 200 GLN 200 219 219 GLN GLN A . n 
A 1 201 LYS 201 220 220 LYS LYS A . n 
A 1 202 ILE 202 221 221 ILE ILE A . n 
A 1 203 GLY 203 222 222 GLY GLY A . n 
A 1 204 ASP 204 223 223 ASP ASP A . n 
A 1 205 ASP 205 224 224 ASP ASP A . n 
A 1 206 LYS 206 225 225 LYS LYS A . n 
A 1 207 LEU 207 226 226 LEU LEU A . n 
A 1 208 ILE 208 227 227 ILE ILE A . n 
A 1 209 VAL 209 228 228 VAL VAL A . n 
A 1 210 TYR 210 229 229 TYR TYR A . n 
A 1 211 ASN 211 230 230 ASN ASN A . n 
A 1 212 GLY 212 231 231 GLY GLY A . n 
A 1 213 ILE 213 232 232 ILE ILE A . n 
A 1 214 ARG 214 233 233 ARG ARG A . n 
A 1 215 SER 215 234 234 SER SER A . n 
A 1 216 THR 216 235 235 THR THR A . n 
A 1 217 PRO 217 236 236 PRO PRO A . n 
A 1 218 ASP 218 237 237 ASP ASP A . n 
A 1 219 TRP 219 238 238 TRP TRP A . n 
A 1 220 SER 220 239 239 SER SER A . n 
A 1 221 ALA 221 240 240 ALA ALA A . n 
A 1 222 GLY 222 241 241 GLY GLY A . n 
A 1 223 PHE 223 242 242 PHE PHE A . n 
A 1 224 ASP 224 243 243 ASP ASP A . n 
A 1 225 PHE 225 244 244 PHE PHE A . n 
A 1 226 ALA 226 245 245 ALA ALA A . n 
A 1 227 GLU 227 246 246 GLU GLU A . n 
A 1 228 TYR 228 247 247 TYR TYR A . n 
A 1 229 THR 229 248 248 THR THR A . n 
A 1 230 ASP 230 249 249 ASP ASP A . n 
A 1 231 ALA 231 250 250 ALA ALA A . n 
A 1 232 ALA 232 251 251 ALA ALA A . n 
A 1 233 MET 233 252 252 MET MET A . n 
A 1 234 ILE 234 253 253 ILE ILE A . n 
A 1 235 GLU 235 254 254 GLU GLU A . n 
A 1 236 HIS 236 255 255 HIS HIS A . n 
A 1 237 PHE 237 256 256 PHE PHE A . n 
A 1 238 GLY 238 257 257 GLY GLY A . n 
A 1 239 HIS 239 258 258 HIS HIS A . n 
A 1 240 PHE 240 259 259 PHE PHE A . n 
A 1 241 GLN 241 260 260 GLN GLN A . n 
A 1 242 SER 242 261 261 SER SER A . n 
A 1 243 ALA 243 262 262 ALA ALA A . n 
A 1 244 SER 244 263 263 SER SER A . n 
A 1 245 LYS 245 264 264 LYS LYS A . n 
A 1 246 GLU 246 265 265 GLU GLU A . n 
A 1 247 THR 247 266 266 THR THR A . n 
A 1 248 MET 248 267 267 MET MET A . n 
A 1 249 LEU 249 268 268 LEU LEU A . n 
A 1 250 ARG 250 269 269 ARG ARG A . n 
A 1 251 ASP 251 270 270 ASP ASP A . n 
A 1 252 ILE 252 271 271 ILE ILE A . n 
A 1 253 LEU 253 272 272 LEU LEU A . n 
A 1 254 GLU 254 273 273 GLU GLU A . n 
A 1 255 MET 255 274 274 MET MET A . n 
A 1 256 GLN 256 275 275 GLN GLN A . n 
A 1 257 ARG 257 276 276 ARG ARG A . n 
A 1 258 ALA 258 277 277 ALA ALA A . n 
A 1 259 ALA 259 278 278 ALA ALA A . n 
A 1 260 LYS 260 279 279 LYS LYS A . n 
A 1 261 ALA 261 280 280 ALA ALA A . n 
A 1 262 GLY 262 281 281 GLY GLY A . n 
A 1 263 LYS 263 282 282 LYS LYS A . n 
A 1 264 ILE 264 283 283 ILE ILE A . n 
A 1 265 VAL 265 284 284 VAL VAL A . n 
A 1 266 VAL 266 285 285 VAL VAL A . n 
A 1 267 LEU 267 286 286 LEU LEU A . n 
A 1 268 LYS 268 287 287 LYS LYS A . n 
A 1 269 GLY 269 288 288 GLY GLY A . n 
A 1 270 TRP 270 289 289 TRP TRP A . n 
A 1 271 ALA 271 290 290 ALA ALA A . n 
A 1 272 GLY 272 291 291 GLY GLY A . n 
A 1 273 PHE 273 292 292 PHE PHE A . n 
A 1 274 THR 274 293 293 THR THR A . n 
A 1 275 PHE 275 294 294 PHE PHE A . n 
A 1 276 ILE 276 295 295 ILE ILE A . n 
A 1 277 ASP 277 296 296 ASP ASP A . n 
A 1 278 ASP 278 297 297 ASP ASP A . n 
A 1 279 GLN 279 298 298 GLN GLN A . n 
A 1 280 ALA 280 299 299 ALA ALA A . n 
A 1 281 MET 281 300 300 MET MET A . n 
A 1 282 ARG 282 301 301 ARG ARG A . n 
A 1 283 LYS 283 302 302 LYS LYS A . n 
A 1 284 PRO 284 303 303 PRO PRO A . n 
A 1 285 LEU 285 304 304 LEU LEU A . n 
A 1 286 THR 286 305 305 THR THR A . n 
A 1 287 GLN 287 306 306 GLN GLN A . n 
A 1 288 LYS 288 307 307 LYS LYS A . n 
A 1 289 ARG 289 308 308 ARG ARG A . n 
A 1 290 ARG 290 309 309 ARG ARG A . n 
A 1 291 VAL 291 310 310 VAL VAL A . n 
A 1 292 ALA 292 311 311 ALA ALA A . n 
A 1 293 LYS 293 312 312 LYS LYS A . n 
A 1 294 ASP 294 313 313 ASP ASP A . n 
A 1 295 SER 295 314 314 SER SER A . n 
A 1 296 LEU 296 315 315 LEU LEU A . n 
A 1 297 LYS 297 316 316 LYS LYS A . n 
A 1 298 PHE 298 317 317 PHE PHE A . n 
A 1 299 PRO 299 318 318 PRO PRO A . n 
A 1 300 LEU 300 319 319 LEU LEU A . n 
A 1 301 ALA 301 320 320 ALA ALA A . n 
A 1 302 CYS 302 321 321 CYS CYS A . n 
A 1 303 PHE 303 322 322 PHE PHE A . n 
A 1 304 LEU 304 323 323 LEU LEU A . n 
A 1 305 ALA 305 324 324 ALA ALA A . n 
A 1 306 GLY 306 325 325 GLY GLY A . n 
A 1 307 ALA 307 326 326 ALA ALA A . n 
A 1 308 GLN 308 327 327 GLN GLN A . n 
A 1 309 GLU 309 328 328 GLU GLU A . n 
A 1 310 ASN 310 329 329 ASN ASN A . n 
A 1 311 CYS 311 330 330 CYS CYS A . n 
A 1 312 TYR 312 331 331 TYR TYR A . n 
A 1 313 PHE 313 332 332 PHE PHE A . n 
A 1 314 ILE 314 333 333 ILE ILE A . n 
A 1 315 TYR 315 334 334 TYR TYR A . n 
A 1 316 ASN 316 335 335 ASN ASN A . n 
A 1 317 TRP 317 336 336 TRP TRP A . n 
A 1 318 GLY 318 337 337 GLY GLY A . n 
A 1 319 TYR 319 338 338 TYR TYR A . n 
A 1 320 ARG 320 339 339 ARG ARG A . n 
A 1 321 MET 321 340 340 MET MET A . n 
A 1 322 GLU 322 341 341 GLU GLU A . n 
A 1 323 ASN 323 342 342 ASN ASN A . n 
A 1 324 GLY 324 343 343 GLY GLY A . n 
A 1 325 CYS 325 344 344 CYS CYS A . n 
A 1 326 LEU 326 345 345 LEU LEU A . n 
A 1 327 GLU 327 346 346 GLU GLU A . n 
A 1 328 TRP 328 347 347 TRP TRP A . n 
A 1 329 TYR 329 348 348 TYR TYR A . n 
A 1 330 PRO 330 349 349 PRO PRO A . n 
A 1 331 GLU 331 350 350 GLU GLU A . n 
A 1 332 PHE 332 351 351 PHE PHE A . n 
A 1 333 ASP 333 352 352 ASP ASP A . n 
A 1 334 LYS 334 353 353 LYS LYS A . n 
A 1 335 PRO 335 354 354 PRO PRO A . n 
A 1 336 LEU 336 355 355 LEU LEU A . n 
A 1 337 GLY 337 356 356 GLY GLY A . n 
A 1 338 LYS 338 357 357 LYS LYS A . n 
A 1 339 PRO 339 358 358 PRO PRO A . n 
A 1 340 VAL 340 359 359 VAL VAL A . n 
A 1 341 GLY 341 360 360 GLY GLY A . n 
A 1 342 GLU 342 361 361 GLU GLU A . n 
A 1 343 MET 343 362 362 MET MET A . n 
A 1 344 VAL 344 363 363 VAL VAL A . n 
A 1 345 ARG 345 364 364 ARG ARG A . n 
A 1 346 ASP 346 365 365 ASP ASP A . n 
A 1 347 GLY 347 366 366 GLY GLY A . n 
A 1 348 TRP 348 367 367 TRP TRP A . n 
A 1 349 LYS 349 368 368 LYS LYS A . n 
A 1 350 LEU 350 369 369 LEU LEU A . n 
A 1 351 SER 351 370 370 SER SER A . n 
A 1 352 ARG 352 371 371 ARG ARG A . n 
A 1 353 GLU 353 372 372 GLU GLU A . n 
A 1 354 TYR 354 373 373 TYR TYR A . n 
A 1 355 LYS 355 374 374 LYS LYS A . n 
A 1 356 HIS 356 375 375 HIS HIS A . n 
A 1 357 ALA 357 376 376 ALA ALA A . n 
A 1 358 SER 358 377 377 SER SER A . n 
A 1 359 VAL 359 378 378 VAL VAL A . n 
A 1 360 ARG 360 379 379 ARG ARG A . n 
A 1 361 VAL 361 380 380 VAL VAL A . n 
A 1 362 ASP 362 381 381 ASP ASP A . n 
A 1 363 LEU 363 382 382 LEU LEU A . n 
A 1 364 GLU 364 383 383 GLU GLU A . n 
A 1 365 SER 365 384 384 SER SER A . n 
A 1 366 LYS 366 385 385 LYS LYS A . n 
A 1 367 GLU 367 386 386 GLU GLU A . n 
A 1 368 ALA 368 387 387 ALA ALA A . n 
A 1 369 GLU 369 388 388 GLU GLU A . n 
A 1 370 ILE 370 389 389 ILE ILE A . n 
A 1 371 ARG 371 390 390 ARG ARG A . n 
A 1 372 TRP 372 391 391 TRP TRP A . n 
A 1 373 ARG 373 392 392 ARG ARG A . n 
B 1 1   MET 1   20  ?   ?   ?   B . n 
B 1 2   HIS 2   21  ?   ?   ?   B . n 
B 1 3   HIS 3   22  ?   ?   ?   B . n 
B 1 4   HIS 4   23  ?   ?   ?   B . n 
B 1 5   HIS 5   24  ?   ?   ?   B . n 
B 1 6   HIS 6   25  ?   ?   ?   B . n 
B 1 7   HIS 7   26  ?   ?   ?   B . n 
B 1 8   GLU 8   27  ?   ?   ?   B . n 
B 1 9   ASN 9   28  ?   ?   ?   B . n 
B 1 10  LEU 10  29  ?   ?   ?   B . n 
B 1 11  TYR 11  30  ?   ?   ?   B . n 
B 1 12  PHE 12  31  ?   ?   ?   B . n 
B 1 13  GLN 13  32  ?   ?   ?   B . n 
B 1 14  GLY 14  33  ?   ?   ?   B . n 
B 1 15  SER 15  34  ?   ?   ?   B . n 
B 1 16  GLY 16  35  ?   ?   ?   B . n 
B 1 17  ASP 17  36  ?   ?   ?   B . n 
B 1 18  GLU 18  37  ?   ?   ?   B . n 
B 1 19  SER 19  38  38  SER SER B . n 
B 1 20  HIS 20  39  39  HIS HIS B . n 
B 1 21  TYR 21  40  40  TYR TYR B . n 
B 1 22  PRO 22  41  41  PRO PRO B . n 
B 1 23  GLU 23  42  42  GLU GLU B . n 
B 1 24  PHE 24  43  43  PHE PHE B . n 
B 1 25  SER 25  44  44  SER SER B . n 
B 1 26  TRP 26  45  45  TRP TRP B . n 
B 1 27  ASP 27  46  46  ASP ASP B . n 
B 1 28  THR 28  47  47  THR THR B . n 
B 1 29  VAL 29  48  48  VAL VAL B . n 
B 1 30  PRO 30  49  49  PRO PRO B . n 
B 1 31  ILE 31  50  50  ILE ILE B . n 
B 1 32  ALA 32  51  51  ALA ALA B . n 
B 1 33  PHE 33  52  52  PHE PHE B . n 
B 1 34  HIS 34  53  53  HIS HIS B . n 
B 1 35  PHE 35  54  54  PHE PHE B . n 
B 1 36  GLY 36  55  55  GLY GLY B . n 
B 1 37  LYS 37  56  56  LYS LYS B . n 
B 1 38  SER 38  57  57  SER SER B . n 
B 1 39  GLN 39  58  58  GLN GLN B . n 
B 1 40  GLY 40  59  59  GLY GLY B . n 
B 1 41  LEU 41  60  60  LEU LEU B . n 
B 1 42  LEU 42  61  61  LEU LEU B . n 
B 1 43  THR 43  62  62  THR THR B . n 
B 1 44  LYS 44  63  63  LYS LYS B . n 
B 1 45  GLU 45  64  64  GLU GLU B . n 
B 1 46  GLU 46  65  65  GLU GLU B . n 
B 1 47  ALA 47  66  66  ALA ALA B . n 
B 1 48  GLU 48  67  67  GLU GLU B . n 
B 1 49  PHE 49  68  68  PHE PHE B . n 
B 1 50  VAL 50  69  69  VAL VAL B . n 
B 1 51  ALA 51  70  70  ALA ALA B . n 
B 1 52  THR 52  71  71  THR THR B . n 
B 1 53  ARG 53  72  72  ARG ARG B . n 
B 1 54  SER 54  73  73  SER SER B . n 
B 1 55  ASN 55  74  74  ASN ASN B . n 
B 1 56  PHE 56  75  75  PHE PHE B . n 
B 1 57  ILE 57  76  76  ILE ILE B . n 
B 1 58  CYS 58  77  77  CYS CYS B . n 
B 1 59  LEU 59  78  78  LEU LEU B . n 
B 1 60  GLU 60  79  79  GLU GLU B . n 
B 1 61  LYS 61  80  80  LYS LYS B . n 
B 1 62  GLY 62  81  81  GLY GLY B . n 
B 1 63  HIS 63  82  82  HIS HIS B . n 
B 1 64  ALA 64  83  83  ALA ALA B . n 
B 1 65  THR 65  84  84  THR THR B . n 
B 1 66  ARG 66  85  85  ARG ARG B . n 
B 1 67  THR 67  86  86  THR THR B . n 
B 1 68  HIS 68  87  87  HIS HIS B . n 
B 1 69  GLY 69  88  88  GLY GLY B . n 
B 1 70  THR 70  89  89  THR THR B . n 
B 1 71  THR 71  90  90  THR THR B . n 
B 1 72  GLU 72  91  91  GLU GLU B . n 
B 1 73  ALA 73  92  92  ALA ALA B . n 
B 1 74  GLY 74  93  93  GLY GLY B . n 
B 1 75  ILE 75  94  94  ILE ILE B . n 
B 1 76  GLU 76  95  95  GLU GLU B . n 
B 1 77  ALA 77  96  96  ALA ALA B . n 
B 1 78  GLU 78  97  97  GLU GLU B . n 
B 1 79  ALA 79  98  98  ALA ALA B . n 
B 1 80  ARG 80  99  99  ARG ARG B . n 
B 1 81  GLN 81  100 100 GLN GLN B . n 
B 1 82  LEU 82  101 101 LEU LEU B . n 
B 1 83  LYS 83  102 102 LYS LYS B . n 
B 1 84  ASN 84  103 103 ASN ASN B . n 
B 1 85  LEU 85  104 104 LEU LEU B . n 
B 1 86  ASN 86  105 105 ASN ASN B . n 
B 1 87  PRO 87  106 106 PRO PRO B . n 
B 1 88  LYS 88  107 107 LYS LYS B . n 
B 1 89  MET 89  108 108 MET MET B . n 
B 1 90  LYS 90  109 109 LYS LYS B . n 
B 1 91  VAL 91  110 110 VAL VAL B . n 
B 1 92  ILE 92  111 111 ILE ILE B . n 
B 1 93  PHE 93  112 112 PHE PHE B . n 
B 1 94  TYR 94  113 113 TYR TYR B . n 
B 1 95  TRP 95  114 114 TRP TRP B . n 
B 1 96  ASN 96  115 115 ASN ASN B . n 
B 1 97  THR 97  116 116 THR THR B . n 
B 1 98  PHE 98  117 117 PHE PHE B . n 
B 1 99  LEU 99  118 118 LEU LEU B . n 
B 1 100 ASP 100 119 119 ASP ASP B . n 
B 1 101 TYR 101 120 120 TYR TYR B . n 
B 1 102 SER 102 121 121 SER SER B . n 
B 1 103 MET 103 122 122 MET MET B . n 
B 1 104 PHE 104 123 123 PHE PHE B . n 
B 1 105 ALA 105 124 124 ALA ALA B . n 
B 1 106 ALA 106 125 125 ALA ALA B . n 
B 1 107 HIS 107 126 126 HIS HIS B . n 
B 1 108 LYS 108 127 127 LYS LYS B . n 
B 1 109 GLU 109 128 128 GLU GLU B . n 
B 1 110 TYR 110 129 129 TYR TYR B . n 
B 1 111 ALA 111 130 130 ALA ALA B . n 
B 1 112 LYS 112 131 131 LYS LYS B . n 
B 1 113 HIS 113 132 132 HIS HIS B . n 
B 1 114 PRO 114 133 133 PRO PRO B . n 
B 1 115 GLN 115 134 134 GLN GLN B . n 
B 1 116 TRP 116 135 135 TRP TRP B . n 
B 1 117 TRP 117 136 136 TRP TRP B . n 
B 1 118 LEU 118 137 137 LEU LEU B . n 
B 1 119 ARG 119 138 138 ARG ARG B . n 
B 1 120 THR 120 139 139 THR THR B . n 
B 1 121 THR 121 140 140 THR THR B . n 
B 1 122 THR 122 141 141 THR THR B . n 
B 1 123 GLY 123 142 142 GLY GLY B . n 
B 1 124 GLU 124 143 143 GLU GLU B . n 
B 1 125 LEU 125 144 144 LEU LEU B . n 
B 1 126 ASP 126 145 145 ASP ASP B . n 
B 1 127 ARG 127 146 146 ARG ARG B . n 
B 1 128 LYS 128 147 147 LYS LYS B . n 
B 1 129 LYS 129 148 148 LYS LYS B . n 
B 1 130 GLY 130 149 149 GLY GLY B . n 
B 1 131 GLN 131 150 150 GLN GLN B . n 
B 1 132 LEU 132 151 151 LEU LEU B . n 
B 1 133 MET 133 152 152 MET MET B . n 
B 1 134 ARG 134 153 153 ARG ARG B . n 
B 1 135 TYR 135 154 154 TYR TYR B . n 
B 1 136 ASP 136 155 155 ASP ASP B . n 
B 1 137 LEU 137 156 156 LEU LEU B . n 
B 1 138 SER 138 157 157 SER SER B . n 
B 1 139 ASN 139 158 158 ASN ASN B . n 
B 1 140 ALA 140 159 159 ALA ALA B . n 
B 1 141 GLU 141 160 160 GLU GLU B . n 
B 1 142 PHE 142 161 161 PHE PHE B . n 
B 1 143 ARG 143 162 162 ARG ARG B . n 
B 1 144 ASN 144 163 163 ASN ASN B . n 
B 1 145 TRP 145 164 164 TRP TRP B . n 
B 1 146 TRP 146 165 165 TRP TRP B . n 
B 1 147 THR 147 166 166 THR THR B . n 
B 1 148 ASN 148 167 167 ASN ASN B . n 
B 1 149 VAL 149 168 168 VAL VAL B . n 
B 1 150 ALA 150 169 169 ALA ALA B . n 
B 1 151 ALA 151 170 170 ALA ALA B . n 
B 1 152 LYS 152 171 171 LYS LYS B . n 
B 1 153 ALA 153 172 172 ALA ALA B . n 
B 1 154 VAL 154 173 173 VAL VAL B . n 
B 1 155 VAL 155 174 174 VAL VAL B . n 
B 1 156 ASP 156 175 175 ASP ASP B . n 
B 1 157 GLY 157 176 176 GLY GLY B . n 
B 1 158 THR 158 177 177 THR THR B . n 
B 1 159 CYS 159 178 178 CYS CYS B . n 
B 1 160 ASP 160 179 179 ASP ASP B . n 
B 1 161 GLY 161 180 180 GLY GLY B . n 
B 1 162 VAL 162 181 181 VAL VAL B . n 
B 1 163 PHE 163 182 182 PHE PHE B . n 
B 1 164 MET 164 183 183 MET MET B . n 
B 1 165 ASP 165 184 184 ASP ASP B . n 
B 1 166 ALA 166 185 185 ALA ALA B . n 
B 1 167 PHE 167 186 186 PHE PHE B . n 
B 1 168 PRO 168 187 187 PRO PRO B . n 
B 1 169 GLN 169 188 188 GLN GLN B . n 
B 1 170 ILE 170 189 189 ILE ILE B . n 
B 1 171 ALA 171 190 190 ALA ALA B . n 
B 1 172 SER 172 191 191 SER SER B . n 
B 1 173 GLN 173 192 192 GLN GLN B . n 
B 1 174 ALA 174 193 193 ALA ALA B . n 
B 1 175 ASN 175 194 194 ASN ASN B . n 
B 1 176 ARG 176 195 195 ARG ARG B . n 
B 1 177 LYS 177 196 196 LYS LYS B . n 
B 1 178 LEU 178 197 197 LEU LEU B . n 
B 1 179 TRP 179 198 198 TRP TRP B . n 
B 1 180 GLY 180 199 199 GLY GLY B . n 
B 1 181 ASP 181 200 200 ASP ASP B . n 
B 1 182 GLU 182 201 201 GLU GLU B . n 
B 1 183 LYS 183 202 202 LYS LYS B . n 
B 1 184 PHE 184 203 203 PHE PHE B . n 
B 1 185 GLU 185 204 204 GLU GLU B . n 
B 1 186 ALA 186 205 205 ALA ALA B . n 
B 1 187 ILE 187 206 206 ILE ILE B . n 
B 1 188 GLN 188 207 207 GLN GLN B . n 
B 1 189 GLN 189 208 208 GLN GLN B . n 
B 1 190 GLY 190 209 209 GLY GLY B . n 
B 1 191 LEU 191 210 210 LEU LEU B . n 
B 1 192 GLN 192 211 211 GLN GLN B . n 
B 1 193 ASP 193 212 212 ASP ASP B . n 
B 1 194 ILE 194 213 213 ILE ILE B . n 
B 1 195 ILE 195 214 214 ILE ILE B . n 
B 1 196 GLN 196 215 215 GLN GLN B . n 
B 1 197 GLU 197 216 216 GLU GLU B . n 
B 1 198 THR 198 217 217 THR THR B . n 
B 1 199 ARG 199 218 218 ARG ARG B . n 
B 1 200 GLN 200 219 219 GLN GLN B . n 
B 1 201 LYS 201 220 220 LYS LYS B . n 
B 1 202 ILE 202 221 221 ILE ILE B . n 
B 1 203 GLY 203 222 222 GLY GLY B . n 
B 1 204 ASP 204 223 223 ASP ASP B . n 
B 1 205 ASP 205 224 224 ASP ASP B . n 
B 1 206 LYS 206 225 225 LYS LYS B . n 
B 1 207 LEU 207 226 226 LEU LEU B . n 
B 1 208 ILE 208 227 227 ILE ILE B . n 
B 1 209 VAL 209 228 228 VAL VAL B . n 
B 1 210 TYR 210 229 229 TYR TYR B . n 
B 1 211 ASN 211 230 230 ASN ASN B . n 
B 1 212 GLY 212 231 231 GLY GLY B . n 
B 1 213 ILE 213 232 232 ILE ILE B . n 
B 1 214 ARG 214 233 233 ARG ARG B . n 
B 1 215 SER 215 234 234 SER SER B . n 
B 1 216 THR 216 235 235 THR THR B . n 
B 1 217 PRO 217 236 236 PRO PRO B . n 
B 1 218 ASP 218 237 237 ASP ASP B . n 
B 1 219 TRP 219 238 238 TRP TRP B . n 
B 1 220 SER 220 239 239 SER SER B . n 
B 1 221 ALA 221 240 240 ALA ALA B . n 
B 1 222 GLY 222 241 241 GLY GLY B . n 
B 1 223 PHE 223 242 242 PHE PHE B . n 
B 1 224 ASP 224 243 243 ASP ASP B . n 
B 1 225 PHE 225 244 244 PHE PHE B . n 
B 1 226 ALA 226 245 245 ALA ALA B . n 
B 1 227 GLU 227 246 246 GLU GLU B . n 
B 1 228 TYR 228 247 247 TYR TYR B . n 
B 1 229 THR 229 248 248 THR THR B . n 
B 1 230 ASP 230 249 249 ASP ASP B . n 
B 1 231 ALA 231 250 250 ALA ALA B . n 
B 1 232 ALA 232 251 251 ALA ALA B . n 
B 1 233 MET 233 252 252 MET MET B . n 
B 1 234 ILE 234 253 253 ILE ILE B . n 
B 1 235 GLU 235 254 254 GLU GLU B . n 
B 1 236 HIS 236 255 255 HIS HIS B . n 
B 1 237 PHE 237 256 256 PHE PHE B . n 
B 1 238 GLY 238 257 257 GLY GLY B . n 
B 1 239 HIS 239 258 258 HIS HIS B . n 
B 1 240 PHE 240 259 259 PHE PHE B . n 
B 1 241 GLN 241 260 260 GLN GLN B . n 
B 1 242 SER 242 261 261 SER SER B . n 
B 1 243 ALA 243 262 262 ALA ALA B . n 
B 1 244 SER 244 263 263 SER SER B . n 
B 1 245 LYS 245 264 264 LYS LYS B . n 
B 1 246 GLU 246 265 265 GLU GLU B . n 
B 1 247 THR 247 266 266 THR THR B . n 
B 1 248 MET 248 267 267 MET MET B . n 
B 1 249 LEU 249 268 268 LEU LEU B . n 
B 1 250 ARG 250 269 269 ARG ARG B . n 
B 1 251 ASP 251 270 270 ASP ASP B . n 
B 1 252 ILE 252 271 271 ILE ILE B . n 
B 1 253 LEU 253 272 272 LEU LEU B . n 
B 1 254 GLU 254 273 273 GLU GLU B . n 
B 1 255 MET 255 274 274 MET MET B . n 
B 1 256 GLN 256 275 275 GLN GLN B . n 
B 1 257 ARG 257 276 276 ARG ARG B . n 
B 1 258 ALA 258 277 277 ALA ALA B . n 
B 1 259 ALA 259 278 278 ALA ALA B . n 
B 1 260 LYS 260 279 279 LYS LYS B . n 
B 1 261 ALA 261 280 280 ALA ALA B . n 
B 1 262 GLY 262 281 281 GLY GLY B . n 
B 1 263 LYS 263 282 282 LYS LYS B . n 
B 1 264 ILE 264 283 283 ILE ILE B . n 
B 1 265 VAL 265 284 284 VAL VAL B . n 
B 1 266 VAL 266 285 285 VAL VAL B . n 
B 1 267 LEU 267 286 286 LEU LEU B . n 
B 1 268 LYS 268 287 287 LYS LYS B . n 
B 1 269 GLY 269 288 288 GLY GLY B . n 
B 1 270 TRP 270 289 289 TRP TRP B . n 
B 1 271 ALA 271 290 290 ALA ALA B . n 
B 1 272 GLY 272 291 291 GLY GLY B . n 
B 1 273 PHE 273 292 292 PHE PHE B . n 
B 1 274 THR 274 293 293 THR THR B . n 
B 1 275 PHE 275 294 294 PHE PHE B . n 
B 1 276 ILE 276 295 295 ILE ILE B . n 
B 1 277 ASP 277 296 296 ASP ASP B . n 
B 1 278 ASP 278 297 297 ASP ASP B . n 
B 1 279 GLN 279 298 298 GLN GLN B . n 
B 1 280 ALA 280 299 299 ALA ALA B . n 
B 1 281 MET 281 300 300 MET MET B . n 
B 1 282 ARG 282 301 301 ARG ARG B . n 
B 1 283 LYS 283 302 302 LYS LYS B . n 
B 1 284 PRO 284 303 303 PRO PRO B . n 
B 1 285 LEU 285 304 304 LEU LEU B . n 
B 1 286 THR 286 305 305 THR THR B . n 
B 1 287 GLN 287 306 306 GLN GLN B . n 
B 1 288 LYS 288 307 307 LYS LYS B . n 
B 1 289 ARG 289 308 308 ARG ARG B . n 
B 1 290 ARG 290 309 309 ARG ARG B . n 
B 1 291 VAL 291 310 310 VAL VAL B . n 
B 1 292 ALA 292 311 311 ALA ALA B . n 
B 1 293 LYS 293 312 312 LYS LYS B . n 
B 1 294 ASP 294 313 313 ASP ASP B . n 
B 1 295 SER 295 314 314 SER SER B . n 
B 1 296 LEU 296 315 315 LEU LEU B . n 
B 1 297 LYS 297 316 316 LYS LYS B . n 
B 1 298 PHE 298 317 317 PHE PHE B . n 
B 1 299 PRO 299 318 318 PRO PRO B . n 
B 1 300 LEU 300 319 319 LEU LEU B . n 
B 1 301 ALA 301 320 320 ALA ALA B . n 
B 1 302 CYS 302 321 321 CYS CYS B . n 
B 1 303 PHE 303 322 322 PHE PHE B . n 
B 1 304 LEU 304 323 323 LEU LEU B . n 
B 1 305 ALA 305 324 324 ALA ALA B . n 
B 1 306 GLY 306 325 325 GLY GLY B . n 
B 1 307 ALA 307 326 326 ALA ALA B . n 
B 1 308 GLN 308 327 327 GLN GLN B . n 
B 1 309 GLU 309 328 328 GLU GLU B . n 
B 1 310 ASN 310 329 329 ASN ASN B . n 
B 1 311 CYS 311 330 330 CYS CYS B . n 
B 1 312 TYR 312 331 331 TYR TYR B . n 
B 1 313 PHE 313 332 332 PHE PHE B . n 
B 1 314 ILE 314 333 333 ILE ILE B . n 
B 1 315 TYR 315 334 334 TYR TYR B . n 
B 1 316 ASN 316 335 335 ASN ASN B . n 
B 1 317 TRP 317 336 336 TRP TRP B . n 
B 1 318 GLY 318 337 337 GLY GLY B . n 
B 1 319 TYR 319 338 338 TYR TYR B . n 
B 1 320 ARG 320 339 339 ARG ARG B . n 
B 1 321 MET 321 340 340 MET MET B . n 
B 1 322 GLU 322 341 341 GLU GLU B . n 
B 1 323 ASN 323 342 342 ASN ASN B . n 
B 1 324 GLY 324 343 343 GLY GLY B . n 
B 1 325 CYS 325 344 344 CYS CYS B . n 
B 1 326 LEU 326 345 345 LEU LEU B . n 
B 1 327 GLU 327 346 346 GLU GLU B . n 
B 1 328 TRP 328 347 347 TRP TRP B . n 
B 1 329 TYR 329 348 348 TYR TYR B . n 
B 1 330 PRO 330 349 349 PRO PRO B . n 
B 1 331 GLU 331 350 350 GLU GLU B . n 
B 1 332 PHE 332 351 351 PHE PHE B . n 
B 1 333 ASP 333 352 352 ASP ASP B . n 
B 1 334 LYS 334 353 353 LYS LYS B . n 
B 1 335 PRO 335 354 354 PRO PRO B . n 
B 1 336 LEU 336 355 355 LEU LEU B . n 
B 1 337 GLY 337 356 356 GLY GLY B . n 
B 1 338 LYS 338 357 357 LYS LYS B . n 
B 1 339 PRO 339 358 358 PRO PRO B . n 
B 1 340 VAL 340 359 359 VAL VAL B . n 
B 1 341 GLY 341 360 360 GLY GLY B . n 
B 1 342 GLU 342 361 361 GLU GLU B . n 
B 1 343 MET 343 362 362 MET MET B . n 
B 1 344 VAL 344 363 363 VAL VAL B . n 
B 1 345 ARG 345 364 364 ARG ARG B . n 
B 1 346 ASP 346 365 365 ASP ASP B . n 
B 1 347 GLY 347 366 366 GLY GLY B . n 
B 1 348 TRP 348 367 367 TRP TRP B . n 
B 1 349 LYS 349 368 368 LYS LYS B . n 
B 1 350 LEU 350 369 369 LEU LEU B . n 
B 1 351 SER 351 370 370 SER SER B . n 
B 1 352 ARG 352 371 371 ARG ARG B . n 
B 1 353 GLU 353 372 372 GLU GLU B . n 
B 1 354 TYR 354 373 373 TYR TYR B . n 
B 1 355 LYS 355 374 374 LYS LYS B . n 
B 1 356 HIS 356 375 375 HIS HIS B . n 
B 1 357 ALA 357 376 376 ALA ALA B . n 
B 1 358 SER 358 377 377 SER SER B . n 
B 1 359 VAL 359 378 378 VAL VAL B . n 
B 1 360 ARG 360 379 379 ARG ARG B . n 
B 1 361 VAL 361 380 380 VAL VAL B . n 
B 1 362 ASP 362 381 381 ASP ASP B . n 
B 1 363 LEU 363 382 382 LEU LEU B . n 
B 1 364 GLU 364 383 383 GLU GLU B . n 
B 1 365 SER 365 384 384 SER SER B . n 
B 1 366 LYS 366 385 385 LYS LYS B . n 
B 1 367 GLU 367 386 386 GLU GLU B . n 
B 1 368 ALA 368 387 387 ALA ALA B . n 
B 1 369 GLU 369 388 388 GLU GLU B . n 
B 1 370 ILE 370 389 389 ILE ILE B . n 
B 1 371 ARG 371 390 390 ARG ARG B . n 
B 1 372 TRP 372 391 391 TRP TRP B . n 
B 1 373 ARG 373 392 392 ARG ARG B . n 
C 1 1   MET 1   20  ?   ?   ?   C . n 
C 1 2   HIS 2   21  ?   ?   ?   C . n 
C 1 3   HIS 3   22  ?   ?   ?   C . n 
C 1 4   HIS 4   23  ?   ?   ?   C . n 
C 1 5   HIS 5   24  ?   ?   ?   C . n 
C 1 6   HIS 6   25  ?   ?   ?   C . n 
C 1 7   HIS 7   26  ?   ?   ?   C . n 
C 1 8   GLU 8   27  ?   ?   ?   C . n 
C 1 9   ASN 9   28  ?   ?   ?   C . n 
C 1 10  LEU 10  29  ?   ?   ?   C . n 
C 1 11  TYR 11  30  ?   ?   ?   C . n 
C 1 12  PHE 12  31  ?   ?   ?   C . n 
C 1 13  GLN 13  32  ?   ?   ?   C . n 
C 1 14  GLY 14  33  ?   ?   ?   C . n 
C 1 15  SER 15  34  ?   ?   ?   C . n 
C 1 16  GLY 16  35  ?   ?   ?   C . n 
C 1 17  ASP 17  36  ?   ?   ?   C . n 
C 1 18  GLU 18  37  37  GLU GLU C . n 
C 1 19  SER 19  38  38  SER SER C . n 
C 1 20  HIS 20  39  39  HIS HIS C . n 
C 1 21  TYR 21  40  40  TYR TYR C . n 
C 1 22  PRO 22  41  41  PRO PRO C . n 
C 1 23  GLU 23  42  42  GLU GLU C . n 
C 1 24  PHE 24  43  43  PHE PHE C . n 
C 1 25  SER 25  44  44  SER SER C . n 
C 1 26  TRP 26  45  45  TRP TRP C . n 
C 1 27  ASP 27  46  46  ASP ASP C . n 
C 1 28  THR 28  47  47  THR THR C . n 
C 1 29  VAL 29  48  48  VAL VAL C . n 
C 1 30  PRO 30  49  49  PRO PRO C . n 
C 1 31  ILE 31  50  50  ILE ILE C . n 
C 1 32  ALA 32  51  51  ALA ALA C . n 
C 1 33  PHE 33  52  52  PHE PHE C . n 
C 1 34  HIS 34  53  53  HIS HIS C . n 
C 1 35  PHE 35  54  54  PHE PHE C . n 
C 1 36  GLY 36  55  55  GLY GLY C . n 
C 1 37  LYS 37  56  56  LYS LYS C . n 
C 1 38  SER 38  57  57  SER SER C . n 
C 1 39  GLN 39  58  58  GLN GLN C . n 
C 1 40  GLY 40  59  59  GLY GLY C . n 
C 1 41  LEU 41  60  60  LEU LEU C . n 
C 1 42  LEU 42  61  61  LEU LEU C . n 
C 1 43  THR 43  62  62  THR THR C . n 
C 1 44  LYS 44  63  63  LYS LYS C . n 
C 1 45  GLU 45  64  64  GLU GLU C . n 
C 1 46  GLU 46  65  65  GLU GLU C . n 
C 1 47  ALA 47  66  66  ALA ALA C . n 
C 1 48  GLU 48  67  67  GLU GLU C . n 
C 1 49  PHE 49  68  68  PHE PHE C . n 
C 1 50  VAL 50  69  69  VAL VAL C . n 
C 1 51  ALA 51  70  70  ALA ALA C . n 
C 1 52  THR 52  71  71  THR THR C . n 
C 1 53  ARG 53  72  72  ARG ARG C . n 
C 1 54  SER 54  73  73  SER SER C . n 
C 1 55  ASN 55  74  74  ASN ASN C . n 
C 1 56  PHE 56  75  75  PHE PHE C . n 
C 1 57  ILE 57  76  76  ILE ILE C . n 
C 1 58  CYS 58  77  77  CYS CYS C . n 
C 1 59  LEU 59  78  78  LEU LEU C . n 
C 1 60  GLU 60  79  79  GLU GLU C . n 
C 1 61  LYS 61  80  80  LYS LYS C . n 
C 1 62  GLY 62  81  81  GLY GLY C . n 
C 1 63  HIS 63  82  82  HIS HIS C . n 
C 1 64  ALA 64  83  83  ALA ALA C . n 
C 1 65  THR 65  84  84  THR THR C . n 
C 1 66  ARG 66  85  85  ARG ARG C . n 
C 1 67  THR 67  86  86  THR THR C . n 
C 1 68  HIS 68  87  87  HIS HIS C . n 
C 1 69  GLY 69  88  88  GLY GLY C . n 
C 1 70  THR 70  89  89  THR THR C . n 
C 1 71  THR 71  90  90  THR THR C . n 
C 1 72  GLU 72  91  91  GLU GLU C . n 
C 1 73  ALA 73  92  92  ALA ALA C . n 
C 1 74  GLY 74  93  93  GLY GLY C . n 
C 1 75  ILE 75  94  94  ILE ILE C . n 
C 1 76  GLU 76  95  95  GLU GLU C . n 
C 1 77  ALA 77  96  96  ALA ALA C . n 
C 1 78  GLU 78  97  97  GLU GLU C . n 
C 1 79  ALA 79  98  98  ALA ALA C . n 
C 1 80  ARG 80  99  99  ARG ARG C . n 
C 1 81  GLN 81  100 100 GLN GLN C . n 
C 1 82  LEU 82  101 101 LEU LEU C . n 
C 1 83  LYS 83  102 102 LYS LYS C . n 
C 1 84  ASN 84  103 103 ASN ASN C . n 
C 1 85  LEU 85  104 104 LEU LEU C . n 
C 1 86  ASN 86  105 105 ASN ASN C . n 
C 1 87  PRO 87  106 106 PRO PRO C . n 
C 1 88  LYS 88  107 107 LYS LYS C . n 
C 1 89  MET 89  108 108 MET MET C . n 
C 1 90  LYS 90  109 109 LYS LYS C . n 
C 1 91  VAL 91  110 110 VAL VAL C . n 
C 1 92  ILE 92  111 111 ILE ILE C . n 
C 1 93  PHE 93  112 112 PHE PHE C . n 
C 1 94  TYR 94  113 113 TYR TYR C . n 
C 1 95  TRP 95  114 114 TRP TRP C . n 
C 1 96  ASN 96  115 115 ASN ASN C . n 
C 1 97  THR 97  116 116 THR THR C . n 
C 1 98  PHE 98  117 117 PHE PHE C . n 
C 1 99  LEU 99  118 118 LEU LEU C . n 
C 1 100 ASP 100 119 119 ASP ASP C . n 
C 1 101 TYR 101 120 120 TYR TYR C . n 
C 1 102 SER 102 121 121 SER SER C . n 
C 1 103 MET 103 122 122 MET MET C . n 
C 1 104 PHE 104 123 123 PHE PHE C . n 
C 1 105 ALA 105 124 124 ALA ALA C . n 
C 1 106 ALA 106 125 125 ALA ALA C . n 
C 1 107 HIS 107 126 126 HIS HIS C . n 
C 1 108 LYS 108 127 127 LYS LYS C . n 
C 1 109 GLU 109 128 128 GLU GLU C . n 
C 1 110 TYR 110 129 129 TYR TYR C . n 
C 1 111 ALA 111 130 130 ALA ALA C . n 
C 1 112 LYS 112 131 131 LYS LYS C . n 
C 1 113 HIS 113 132 132 HIS HIS C . n 
C 1 114 PRO 114 133 133 PRO PRO C . n 
C 1 115 GLN 115 134 134 GLN GLN C . n 
C 1 116 TRP 116 135 135 TRP TRP C . n 
C 1 117 TRP 117 136 136 TRP TRP C . n 
C 1 118 LEU 118 137 137 LEU LEU C . n 
C 1 119 ARG 119 138 138 ARG ARG C . n 
C 1 120 THR 120 139 139 THR THR C . n 
C 1 121 THR 121 140 140 THR THR C . n 
C 1 122 THR 122 141 141 THR THR C . n 
C 1 123 GLY 123 142 142 GLY GLY C . n 
C 1 124 GLU 124 143 143 GLU GLU C . n 
C 1 125 LEU 125 144 144 LEU LEU C . n 
C 1 126 ASP 126 145 145 ASP ASP C . n 
C 1 127 ARG 127 146 146 ARG ARG C . n 
C 1 128 LYS 128 147 147 LYS LYS C . n 
C 1 129 LYS 129 148 148 LYS LYS C . n 
C 1 130 GLY 130 149 149 GLY GLY C . n 
C 1 131 GLN 131 150 150 GLN GLN C . n 
C 1 132 LEU 132 151 151 LEU LEU C . n 
C 1 133 MET 133 152 152 MET MET C . n 
C 1 134 ARG 134 153 153 ARG ARG C . n 
C 1 135 TYR 135 154 154 TYR TYR C . n 
C 1 136 ASP 136 155 155 ASP ASP C . n 
C 1 137 LEU 137 156 156 LEU LEU C . n 
C 1 138 SER 138 157 157 SER SER C . n 
C 1 139 ASN 139 158 158 ASN ASN C . n 
C 1 140 ALA 140 159 159 ALA ALA C . n 
C 1 141 GLU 141 160 160 GLU GLU C . n 
C 1 142 PHE 142 161 161 PHE PHE C . n 
C 1 143 ARG 143 162 162 ARG ARG C . n 
C 1 144 ASN 144 163 163 ASN ASN C . n 
C 1 145 TRP 145 164 164 TRP TRP C . n 
C 1 146 TRP 146 165 165 TRP TRP C . n 
C 1 147 THR 147 166 166 THR THR C . n 
C 1 148 ASN 148 167 167 ASN ASN C . n 
C 1 149 VAL 149 168 168 VAL VAL C . n 
C 1 150 ALA 150 169 169 ALA ALA C . n 
C 1 151 ALA 151 170 170 ALA ALA C . n 
C 1 152 LYS 152 171 171 LYS LYS C . n 
C 1 153 ALA 153 172 172 ALA ALA C . n 
C 1 154 VAL 154 173 173 VAL VAL C . n 
C 1 155 VAL 155 174 174 VAL VAL C . n 
C 1 156 ASP 156 175 175 ASP ASP C . n 
C 1 157 GLY 157 176 176 GLY GLY C . n 
C 1 158 THR 158 177 177 THR THR C . n 
C 1 159 CYS 159 178 178 CYS CYS C . n 
C 1 160 ASP 160 179 179 ASP ASP C . n 
C 1 161 GLY 161 180 180 GLY GLY C . n 
C 1 162 VAL 162 181 181 VAL VAL C . n 
C 1 163 PHE 163 182 182 PHE PHE C . n 
C 1 164 MET 164 183 183 MET MET C . n 
C 1 165 ASP 165 184 184 ASP ASP C . n 
C 1 166 ALA 166 185 185 ALA ALA C . n 
C 1 167 PHE 167 186 186 PHE PHE C . n 
C 1 168 PRO 168 187 187 PRO PRO C . n 
C 1 169 GLN 169 188 188 GLN GLN C . n 
C 1 170 ILE 170 189 189 ILE ILE C . n 
C 1 171 ALA 171 190 190 ALA ALA C . n 
C 1 172 SER 172 191 191 SER SER C . n 
C 1 173 GLN 173 192 192 GLN GLN C . n 
C 1 174 ALA 174 193 193 ALA ALA C . n 
C 1 175 ASN 175 194 194 ASN ASN C . n 
C 1 176 ARG 176 195 195 ARG ARG C . n 
C 1 177 LYS 177 196 196 LYS LYS C . n 
C 1 178 LEU 178 197 197 LEU LEU C . n 
C 1 179 TRP 179 198 198 TRP TRP C . n 
C 1 180 GLY 180 199 199 GLY GLY C . n 
C 1 181 ASP 181 200 200 ASP ASP C . n 
C 1 182 GLU 182 201 201 GLU GLU C . n 
C 1 183 LYS 183 202 202 LYS LYS C . n 
C 1 184 PHE 184 203 203 PHE PHE C . n 
C 1 185 GLU 185 204 204 GLU GLU C . n 
C 1 186 ALA 186 205 205 ALA ALA C . n 
C 1 187 ILE 187 206 206 ILE ILE C . n 
C 1 188 GLN 188 207 207 GLN GLN C . n 
C 1 189 GLN 189 208 208 GLN GLN C . n 
C 1 190 GLY 190 209 209 GLY GLY C . n 
C 1 191 LEU 191 210 210 LEU LEU C . n 
C 1 192 GLN 192 211 211 GLN GLN C . n 
C 1 193 ASP 193 212 212 ASP ASP C . n 
C 1 194 ILE 194 213 213 ILE ILE C . n 
C 1 195 ILE 195 214 214 ILE ILE C . n 
C 1 196 GLN 196 215 215 GLN GLN C . n 
C 1 197 GLU 197 216 216 GLU GLU C . n 
C 1 198 THR 198 217 217 THR THR C . n 
C 1 199 ARG 199 218 218 ARG ARG C . n 
C 1 200 GLN 200 219 219 GLN GLN C . n 
C 1 201 LYS 201 220 220 LYS LYS C . n 
C 1 202 ILE 202 221 221 ILE ILE C . n 
C 1 203 GLY 203 222 222 GLY GLY C . n 
C 1 204 ASP 204 223 223 ASP ASP C . n 
C 1 205 ASP 205 224 224 ASP ASP C . n 
C 1 206 LYS 206 225 225 LYS LYS C . n 
C 1 207 LEU 207 226 226 LEU LEU C . n 
C 1 208 ILE 208 227 227 ILE ILE C . n 
C 1 209 VAL 209 228 228 VAL VAL C . n 
C 1 210 TYR 210 229 229 TYR TYR C . n 
C 1 211 ASN 211 230 230 ASN ASN C . n 
C 1 212 GLY 212 231 231 GLY GLY C . n 
C 1 213 ILE 213 232 232 ILE ILE C . n 
C 1 214 ARG 214 233 233 ARG ARG C . n 
C 1 215 SER 215 234 234 SER SER C . n 
C 1 216 THR 216 235 235 THR THR C . n 
C 1 217 PRO 217 236 236 PRO PRO C . n 
C 1 218 ASP 218 237 237 ASP ASP C . n 
C 1 219 TRP 219 238 238 TRP TRP C . n 
C 1 220 SER 220 239 239 SER SER C . n 
C 1 221 ALA 221 240 240 ALA ALA C . n 
C 1 222 GLY 222 241 241 GLY GLY C . n 
C 1 223 PHE 223 242 242 PHE PHE C . n 
C 1 224 ASP 224 243 243 ASP ASP C . n 
C 1 225 PHE 225 244 244 PHE PHE C . n 
C 1 226 ALA 226 245 245 ALA ALA C . n 
C 1 227 GLU 227 246 246 GLU GLU C . n 
C 1 228 TYR 228 247 247 TYR TYR C . n 
C 1 229 THR 229 248 248 THR THR C . n 
C 1 230 ASP 230 249 249 ASP ASP C . n 
C 1 231 ALA 231 250 250 ALA ALA C . n 
C 1 232 ALA 232 251 251 ALA ALA C . n 
C 1 233 MET 233 252 252 MET MET C . n 
C 1 234 ILE 234 253 253 ILE ILE C . n 
C 1 235 GLU 235 254 254 GLU GLU C . n 
C 1 236 HIS 236 255 255 HIS HIS C . n 
C 1 237 PHE 237 256 256 PHE PHE C . n 
C 1 238 GLY 238 257 257 GLY GLY C . n 
C 1 239 HIS 239 258 258 HIS HIS C . n 
C 1 240 PHE 240 259 259 PHE PHE C . n 
C 1 241 GLN 241 260 260 GLN GLN C . n 
C 1 242 SER 242 261 261 SER SER C . n 
C 1 243 ALA 243 262 262 ALA ALA C . n 
C 1 244 SER 244 263 263 SER SER C . n 
C 1 245 LYS 245 264 264 LYS LYS C . n 
C 1 246 GLU 246 265 265 GLU GLU C . n 
C 1 247 THR 247 266 266 THR THR C . n 
C 1 248 MET 248 267 267 MET MET C . n 
C 1 249 LEU 249 268 268 LEU LEU C . n 
C 1 250 ARG 250 269 269 ARG ARG C . n 
C 1 251 ASP 251 270 270 ASP ASP C . n 
C 1 252 ILE 252 271 271 ILE ILE C . n 
C 1 253 LEU 253 272 272 LEU LEU C . n 
C 1 254 GLU 254 273 273 GLU GLU C . n 
C 1 255 MET 255 274 274 MET MET C . n 
C 1 256 GLN 256 275 275 GLN GLN C . n 
C 1 257 ARG 257 276 276 ARG ARG C . n 
C 1 258 ALA 258 277 277 ALA ALA C . n 
C 1 259 ALA 259 278 278 ALA ALA C . n 
C 1 260 LYS 260 279 279 LYS LYS C . n 
C 1 261 ALA 261 280 280 ALA ALA C . n 
C 1 262 GLY 262 281 281 GLY GLY C . n 
C 1 263 LYS 263 282 282 LYS LYS C . n 
C 1 264 ILE 264 283 283 ILE ILE C . n 
C 1 265 VAL 265 284 284 VAL VAL C . n 
C 1 266 VAL 266 285 285 VAL VAL C . n 
C 1 267 LEU 267 286 286 LEU LEU C . n 
C 1 268 LYS 268 287 287 LYS LYS C . n 
C 1 269 GLY 269 288 288 GLY GLY C . n 
C 1 270 TRP 270 289 289 TRP TRP C . n 
C 1 271 ALA 271 290 290 ALA ALA C . n 
C 1 272 GLY 272 291 291 GLY GLY C . n 
C 1 273 PHE 273 292 292 PHE PHE C . n 
C 1 274 THR 274 293 293 THR THR C . n 
C 1 275 PHE 275 294 294 PHE PHE C . n 
C 1 276 ILE 276 295 295 ILE ILE C . n 
C 1 277 ASP 277 296 296 ASP ASP C . n 
C 1 278 ASP 278 297 297 ASP ASP C . n 
C 1 279 GLN 279 298 298 GLN GLN C . n 
C 1 280 ALA 280 299 299 ALA ALA C . n 
C 1 281 MET 281 300 300 MET MET C . n 
C 1 282 ARG 282 301 301 ARG ARG C . n 
C 1 283 LYS 283 302 302 LYS LYS C . n 
C 1 284 PRO 284 303 303 PRO PRO C . n 
C 1 285 LEU 285 304 304 LEU LEU C . n 
C 1 286 THR 286 305 305 THR THR C . n 
C 1 287 GLN 287 306 306 GLN GLN C . n 
C 1 288 LYS 288 307 307 LYS LYS C . n 
C 1 289 ARG 289 308 308 ARG ARG C . n 
C 1 290 ARG 290 309 309 ARG ARG C . n 
C 1 291 VAL 291 310 310 VAL VAL C . n 
C 1 292 ALA 292 311 311 ALA ALA C . n 
C 1 293 LYS 293 312 312 LYS LYS C . n 
C 1 294 ASP 294 313 313 ASP ASP C . n 
C 1 295 SER 295 314 314 SER SER C . n 
C 1 296 LEU 296 315 315 LEU LEU C . n 
C 1 297 LYS 297 316 316 LYS LYS C . n 
C 1 298 PHE 298 317 317 PHE PHE C . n 
C 1 299 PRO 299 318 318 PRO PRO C . n 
C 1 300 LEU 300 319 319 LEU LEU C . n 
C 1 301 ALA 301 320 320 ALA ALA C . n 
C 1 302 CYS 302 321 321 CYS CYS C . n 
C 1 303 PHE 303 322 322 PHE PHE C . n 
C 1 304 LEU 304 323 323 LEU LEU C . n 
C 1 305 ALA 305 324 324 ALA ALA C . n 
C 1 306 GLY 306 325 325 GLY GLY C . n 
C 1 307 ALA 307 326 326 ALA ALA C . n 
C 1 308 GLN 308 327 327 GLN GLN C . n 
C 1 309 GLU 309 328 328 GLU GLU C . n 
C 1 310 ASN 310 329 329 ASN ASN C . n 
C 1 311 CYS 311 330 330 CYS CYS C . n 
C 1 312 TYR 312 331 331 TYR TYR C . n 
C 1 313 PHE 313 332 332 PHE PHE C . n 
C 1 314 ILE 314 333 333 ILE ILE C . n 
C 1 315 TYR 315 334 334 TYR TYR C . n 
C 1 316 ASN 316 335 335 ASN ASN C . n 
C 1 317 TRP 317 336 336 TRP TRP C . n 
C 1 318 GLY 318 337 337 GLY GLY C . n 
C 1 319 TYR 319 338 338 TYR TYR C . n 
C 1 320 ARG 320 339 339 ARG ARG C . n 
C 1 321 MET 321 340 340 MET MET C . n 
C 1 322 GLU 322 341 341 GLU GLU C . n 
C 1 323 ASN 323 342 342 ASN ASN C . n 
C 1 324 GLY 324 343 343 GLY GLY C . n 
C 1 325 CYS 325 344 344 CYS CYS C . n 
C 1 326 LEU 326 345 345 LEU LEU C . n 
C 1 327 GLU 327 346 346 GLU GLU C . n 
C 1 328 TRP 328 347 347 TRP TRP C . n 
C 1 329 TYR 329 348 348 TYR TYR C . n 
C 1 330 PRO 330 349 349 PRO PRO C . n 
C 1 331 GLU 331 350 350 GLU GLU C . n 
C 1 332 PHE 332 351 351 PHE PHE C . n 
C 1 333 ASP 333 352 352 ASP ASP C . n 
C 1 334 LYS 334 353 353 LYS LYS C . n 
C 1 335 PRO 335 354 354 PRO PRO C . n 
C 1 336 LEU 336 355 355 LEU LEU C . n 
C 1 337 GLY 337 356 356 GLY GLY C . n 
C 1 338 LYS 338 357 357 LYS LYS C . n 
C 1 339 PRO 339 358 358 PRO PRO C . n 
C 1 340 VAL 340 359 359 VAL VAL C . n 
C 1 341 GLY 341 360 360 GLY GLY C . n 
C 1 342 GLU 342 361 361 GLU GLU C . n 
C 1 343 MET 343 362 362 MET MET C . n 
C 1 344 VAL 344 363 363 VAL VAL C . n 
C 1 345 ARG 345 364 364 ARG ARG C . n 
C 1 346 ASP 346 365 365 ASP ASP C . n 
C 1 347 GLY 347 366 366 GLY GLY C . n 
C 1 348 TRP 348 367 367 TRP TRP C . n 
C 1 349 LYS 349 368 368 LYS LYS C . n 
C 1 350 LEU 350 369 369 LEU LEU C . n 
C 1 351 SER 351 370 370 SER SER C . n 
C 1 352 ARG 352 371 371 ARG ARG C . n 
C 1 353 GLU 353 372 372 GLU GLU C . n 
C 1 354 TYR 354 373 373 TYR TYR C . n 
C 1 355 LYS 355 374 374 LYS LYS C . n 
C 1 356 HIS 356 375 375 HIS HIS C . n 
C 1 357 ALA 357 376 376 ALA ALA C . n 
C 1 358 SER 358 377 377 SER SER C . n 
C 1 359 VAL 359 378 378 VAL VAL C . n 
C 1 360 ARG 360 379 379 ARG ARG C . n 
C 1 361 VAL 361 380 380 VAL VAL C . n 
C 1 362 ASP 362 381 381 ASP ASP C . n 
C 1 363 LEU 363 382 382 LEU LEU C . n 
C 1 364 GLU 364 383 383 GLU GLU C . n 
C 1 365 SER 365 384 384 SER SER C . n 
C 1 366 LYS 366 385 385 LYS LYS C . n 
C 1 367 GLU 367 386 386 GLU GLU C . n 
C 1 368 ALA 368 387 387 ALA ALA C . n 
C 1 369 GLU 369 388 388 GLU GLU C . n 
C 1 370 ILE 370 389 389 ILE ILE C . n 
C 1 371 ARG 371 390 390 ARG ARG C . n 
C 1 372 TRP 372 391 391 TRP TRP C . n 
C 1 373 ARG 373 392 392 ARG ARG C . n 
D 1 1   MET 1   20  ?   ?   ?   D . n 
D 1 2   HIS 2   21  ?   ?   ?   D . n 
D 1 3   HIS 3   22  ?   ?   ?   D . n 
D 1 4   HIS 4   23  ?   ?   ?   D . n 
D 1 5   HIS 5   24  ?   ?   ?   D . n 
D 1 6   HIS 6   25  ?   ?   ?   D . n 
D 1 7   HIS 7   26  ?   ?   ?   D . n 
D 1 8   GLU 8   27  ?   ?   ?   D . n 
D 1 9   ASN 9   28  ?   ?   ?   D . n 
D 1 10  LEU 10  29  ?   ?   ?   D . n 
D 1 11  TYR 11  30  ?   ?   ?   D . n 
D 1 12  PHE 12  31  ?   ?   ?   D . n 
D 1 13  GLN 13  32  ?   ?   ?   D . n 
D 1 14  GLY 14  33  ?   ?   ?   D . n 
D 1 15  SER 15  34  ?   ?   ?   D . n 
D 1 16  GLY 16  35  ?   ?   ?   D . n 
D 1 17  ASP 17  36  ?   ?   ?   D . n 
D 1 18  GLU 18  37  37  GLU GLU D . n 
D 1 19  SER 19  38  38  SER SER D . n 
D 1 20  HIS 20  39  39  HIS HIS D . n 
D 1 21  TYR 21  40  40  TYR TYR D . n 
D 1 22  PRO 22  41  41  PRO PRO D . n 
D 1 23  GLU 23  42  42  GLU GLU D . n 
D 1 24  PHE 24  43  43  PHE PHE D . n 
D 1 25  SER 25  44  44  SER SER D . n 
D 1 26  TRP 26  45  45  TRP TRP D . n 
D 1 27  ASP 27  46  46  ASP ASP D . n 
D 1 28  THR 28  47  47  THR THR D . n 
D 1 29  VAL 29  48  48  VAL VAL D . n 
D 1 30  PRO 30  49  49  PRO PRO D . n 
D 1 31  ILE 31  50  50  ILE ILE D . n 
D 1 32  ALA 32  51  51  ALA ALA D . n 
D 1 33  PHE 33  52  52  PHE PHE D . n 
D 1 34  HIS 34  53  53  HIS HIS D . n 
D 1 35  PHE 35  54  54  PHE PHE D . n 
D 1 36  GLY 36  55  55  GLY GLY D . n 
D 1 37  LYS 37  56  56  LYS LYS D . n 
D 1 38  SER 38  57  57  SER SER D . n 
D 1 39  GLN 39  58  58  GLN GLN D . n 
D 1 40  GLY 40  59  59  GLY GLY D . n 
D 1 41  LEU 41  60  60  LEU LEU D . n 
D 1 42  LEU 42  61  61  LEU LEU D . n 
D 1 43  THR 43  62  62  THR THR D . n 
D 1 44  LYS 44  63  63  LYS LYS D . n 
D 1 45  GLU 45  64  64  GLU GLU D . n 
D 1 46  GLU 46  65  65  GLU GLU D . n 
D 1 47  ALA 47  66  66  ALA ALA D . n 
D 1 48  GLU 48  67  67  GLU GLU D . n 
D 1 49  PHE 49  68  68  PHE PHE D . n 
D 1 50  VAL 50  69  69  VAL VAL D . n 
D 1 51  ALA 51  70  70  ALA ALA D . n 
D 1 52  THR 52  71  71  THR THR D . n 
D 1 53  ARG 53  72  72  ARG ARG D . n 
D 1 54  SER 54  73  73  SER SER D . n 
D 1 55  ASN 55  74  74  ASN ASN D . n 
D 1 56  PHE 56  75  75  PHE PHE D . n 
D 1 57  ILE 57  76  76  ILE ILE D . n 
D 1 58  CYS 58  77  77  CYS CYS D . n 
D 1 59  LEU 59  78  78  LEU LEU D . n 
D 1 60  GLU 60  79  79  GLU GLU D . n 
D 1 61  LYS 61  80  80  LYS LYS D . n 
D 1 62  GLY 62  81  81  GLY GLY D . n 
D 1 63  HIS 63  82  82  HIS HIS D . n 
D 1 64  ALA 64  83  83  ALA ALA D . n 
D 1 65  THR 65  84  84  THR THR D . n 
D 1 66  ARG 66  85  85  ARG ARG D . n 
D 1 67  THR 67  86  86  THR THR D . n 
D 1 68  HIS 68  87  87  HIS HIS D . n 
D 1 69  GLY 69  88  88  GLY GLY D . n 
D 1 70  THR 70  89  89  THR THR D . n 
D 1 71  THR 71  90  90  THR THR D . n 
D 1 72  GLU 72  91  91  GLU GLU D . n 
D 1 73  ALA 73  92  92  ALA ALA D . n 
D 1 74  GLY 74  93  93  GLY GLY D . n 
D 1 75  ILE 75  94  94  ILE ILE D . n 
D 1 76  GLU 76  95  95  GLU GLU D . n 
D 1 77  ALA 77  96  96  ALA ALA D . n 
D 1 78  GLU 78  97  97  GLU GLU D . n 
D 1 79  ALA 79  98  98  ALA ALA D . n 
D 1 80  ARG 80  99  99  ARG ARG D . n 
D 1 81  GLN 81  100 100 GLN GLN D . n 
D 1 82  LEU 82  101 101 LEU LEU D . n 
D 1 83  LYS 83  102 102 LYS LYS D . n 
D 1 84  ASN 84  103 103 ASN ASN D . n 
D 1 85  LEU 85  104 104 LEU LEU D . n 
D 1 86  ASN 86  105 105 ASN ASN D . n 
D 1 87  PRO 87  106 106 PRO PRO D . n 
D 1 88  LYS 88  107 107 LYS LYS D . n 
D 1 89  MET 89  108 108 MET MET D . n 
D 1 90  LYS 90  109 109 LYS LYS D . n 
D 1 91  VAL 91  110 110 VAL VAL D . n 
D 1 92  ILE 92  111 111 ILE ILE D . n 
D 1 93  PHE 93  112 112 PHE PHE D . n 
D 1 94  TYR 94  113 113 TYR TYR D . n 
D 1 95  TRP 95  114 114 TRP TRP D . n 
D 1 96  ASN 96  115 115 ASN ASN D . n 
D 1 97  THR 97  116 116 THR THR D . n 
D 1 98  PHE 98  117 117 PHE PHE D . n 
D 1 99  LEU 99  118 118 LEU LEU D . n 
D 1 100 ASP 100 119 119 ASP ASP D . n 
D 1 101 TYR 101 120 120 TYR TYR D . n 
D 1 102 SER 102 121 121 SER SER D . n 
D 1 103 MET 103 122 122 MET MET D . n 
D 1 104 PHE 104 123 123 PHE PHE D . n 
D 1 105 ALA 105 124 124 ALA ALA D . n 
D 1 106 ALA 106 125 125 ALA ALA D . n 
D 1 107 HIS 107 126 126 HIS HIS D . n 
D 1 108 LYS 108 127 127 LYS LYS D . n 
D 1 109 GLU 109 128 128 GLU GLU D . n 
D 1 110 TYR 110 129 129 TYR TYR D . n 
D 1 111 ALA 111 130 130 ALA ALA D . n 
D 1 112 LYS 112 131 131 LYS LYS D . n 
D 1 113 HIS 113 132 132 HIS HIS D . n 
D 1 114 PRO 114 133 133 PRO PRO D . n 
D 1 115 GLN 115 134 134 GLN GLN D . n 
D 1 116 TRP 116 135 135 TRP TRP D . n 
D 1 117 TRP 117 136 136 TRP TRP D . n 
D 1 118 LEU 118 137 137 LEU LEU D . n 
D 1 119 ARG 119 138 138 ARG ARG D . n 
D 1 120 THR 120 139 139 THR THR D . n 
D 1 121 THR 121 140 140 THR THR D . n 
D 1 122 THR 122 141 141 THR THR D . n 
D 1 123 GLY 123 142 142 GLY GLY D . n 
D 1 124 GLU 124 143 143 GLU GLU D . n 
D 1 125 LEU 125 144 144 LEU LEU D . n 
D 1 126 ASP 126 145 145 ASP ASP D . n 
D 1 127 ARG 127 146 146 ARG ARG D . n 
D 1 128 LYS 128 147 147 LYS LYS D . n 
D 1 129 LYS 129 148 148 LYS LYS D . n 
D 1 130 GLY 130 149 149 GLY GLY D . n 
D 1 131 GLN 131 150 150 GLN GLN D . n 
D 1 132 LEU 132 151 151 LEU LEU D . n 
D 1 133 MET 133 152 152 MET MET D . n 
D 1 134 ARG 134 153 153 ARG ARG D . n 
D 1 135 TYR 135 154 154 TYR TYR D . n 
D 1 136 ASP 136 155 155 ASP ASP D . n 
D 1 137 LEU 137 156 156 LEU LEU D . n 
D 1 138 SER 138 157 157 SER SER D . n 
D 1 139 ASN 139 158 158 ASN ASN D . n 
D 1 140 ALA 140 159 159 ALA ALA D . n 
D 1 141 GLU 141 160 160 GLU GLU D . n 
D 1 142 PHE 142 161 161 PHE PHE D . n 
D 1 143 ARG 143 162 162 ARG ARG D . n 
D 1 144 ASN 144 163 163 ASN ASN D . n 
D 1 145 TRP 145 164 164 TRP TRP D . n 
D 1 146 TRP 146 165 165 TRP TRP D . n 
D 1 147 THR 147 166 166 THR THR D . n 
D 1 148 ASN 148 167 167 ASN ASN D . n 
D 1 149 VAL 149 168 168 VAL VAL D . n 
D 1 150 ALA 150 169 169 ALA ALA D . n 
D 1 151 ALA 151 170 170 ALA ALA D . n 
D 1 152 LYS 152 171 171 LYS LYS D . n 
D 1 153 ALA 153 172 172 ALA ALA D . n 
D 1 154 VAL 154 173 173 VAL VAL D . n 
D 1 155 VAL 155 174 174 VAL VAL D . n 
D 1 156 ASP 156 175 175 ASP ASP D . n 
D 1 157 GLY 157 176 176 GLY GLY D . n 
D 1 158 THR 158 177 177 THR THR D . n 
D 1 159 CYS 159 178 178 CYS CYS D . n 
D 1 160 ASP 160 179 179 ASP ASP D . n 
D 1 161 GLY 161 180 180 GLY GLY D . n 
D 1 162 VAL 162 181 181 VAL VAL D . n 
D 1 163 PHE 163 182 182 PHE PHE D . n 
D 1 164 MET 164 183 183 MET MET D . n 
D 1 165 ASP 165 184 184 ASP ASP D . n 
D 1 166 ALA 166 185 185 ALA ALA D . n 
D 1 167 PHE 167 186 186 PHE PHE D . n 
D 1 168 PRO 168 187 187 PRO PRO D . n 
D 1 169 GLN 169 188 188 GLN GLN D . n 
D 1 170 ILE 170 189 189 ILE ILE D . n 
D 1 171 ALA 171 190 190 ALA ALA D . n 
D 1 172 SER 172 191 191 SER SER D . n 
D 1 173 GLN 173 192 192 GLN GLN D . n 
D 1 174 ALA 174 193 193 ALA ALA D . n 
D 1 175 ASN 175 194 194 ASN ASN D . n 
D 1 176 ARG 176 195 195 ARG ARG D . n 
D 1 177 LYS 177 196 196 LYS LYS D . n 
D 1 178 LEU 178 197 197 LEU LEU D . n 
D 1 179 TRP 179 198 198 TRP TRP D . n 
D 1 180 GLY 180 199 199 GLY GLY D . n 
D 1 181 ASP 181 200 200 ASP ASP D . n 
D 1 182 GLU 182 201 201 GLU GLU D . n 
D 1 183 LYS 183 202 202 LYS LYS D . n 
D 1 184 PHE 184 203 203 PHE PHE D . n 
D 1 185 GLU 185 204 204 GLU GLU D . n 
D 1 186 ALA 186 205 205 ALA ALA D . n 
D 1 187 ILE 187 206 206 ILE ILE D . n 
D 1 188 GLN 188 207 207 GLN GLN D . n 
D 1 189 GLN 189 208 208 GLN GLN D . n 
D 1 190 GLY 190 209 209 GLY GLY D . n 
D 1 191 LEU 191 210 210 LEU LEU D . n 
D 1 192 GLN 192 211 211 GLN GLN D . n 
D 1 193 ASP 193 212 212 ASP ASP D . n 
D 1 194 ILE 194 213 213 ILE ILE D . n 
D 1 195 ILE 195 214 214 ILE ILE D . n 
D 1 196 GLN 196 215 215 GLN GLN D . n 
D 1 197 GLU 197 216 216 GLU GLU D . n 
D 1 198 THR 198 217 217 THR THR D . n 
D 1 199 ARG 199 218 218 ARG ARG D . n 
D 1 200 GLN 200 219 219 GLN GLN D . n 
D 1 201 LYS 201 220 220 LYS LYS D . n 
D 1 202 ILE 202 221 221 ILE ILE D . n 
D 1 203 GLY 203 222 222 GLY GLY D . n 
D 1 204 ASP 204 223 223 ASP ASP D . n 
D 1 205 ASP 205 224 224 ASP ASP D . n 
D 1 206 LYS 206 225 225 LYS LYS D . n 
D 1 207 LEU 207 226 226 LEU LEU D . n 
D 1 208 ILE 208 227 227 ILE ILE D . n 
D 1 209 VAL 209 228 228 VAL VAL D . n 
D 1 210 TYR 210 229 229 TYR TYR D . n 
D 1 211 ASN 211 230 230 ASN ASN D . n 
D 1 212 GLY 212 231 231 GLY GLY D . n 
D 1 213 ILE 213 232 232 ILE ILE D . n 
D 1 214 ARG 214 233 233 ARG ARG D . n 
D 1 215 SER 215 234 234 SER SER D . n 
D 1 216 THR 216 235 235 THR THR D . n 
D 1 217 PRO 217 236 236 PRO PRO D . n 
D 1 218 ASP 218 237 237 ASP ASP D . n 
D 1 219 TRP 219 238 238 TRP TRP D . n 
D 1 220 SER 220 239 239 SER SER D . n 
D 1 221 ALA 221 240 240 ALA ALA D . n 
D 1 222 GLY 222 241 241 GLY GLY D . n 
D 1 223 PHE 223 242 242 PHE PHE D . n 
D 1 224 ASP 224 243 243 ASP ASP D . n 
D 1 225 PHE 225 244 244 PHE PHE D . n 
D 1 226 ALA 226 245 245 ALA ALA D . n 
D 1 227 GLU 227 246 246 GLU GLU D . n 
D 1 228 TYR 228 247 247 TYR TYR D . n 
D 1 229 THR 229 248 248 THR THR D . n 
D 1 230 ASP 230 249 249 ASP ASP D . n 
D 1 231 ALA 231 250 250 ALA ALA D . n 
D 1 232 ALA 232 251 251 ALA ALA D . n 
D 1 233 MET 233 252 252 MET MET D . n 
D 1 234 ILE 234 253 253 ILE ILE D . n 
D 1 235 GLU 235 254 254 GLU GLU D . n 
D 1 236 HIS 236 255 255 HIS HIS D . n 
D 1 237 PHE 237 256 256 PHE PHE D . n 
D 1 238 GLY 238 257 257 GLY GLY D . n 
D 1 239 HIS 239 258 258 HIS HIS D . n 
D 1 240 PHE 240 259 259 PHE PHE D . n 
D 1 241 GLN 241 260 260 GLN GLN D . n 
D 1 242 SER 242 261 261 SER SER D . n 
D 1 243 ALA 243 262 262 ALA ALA D . n 
D 1 244 SER 244 263 263 SER SER D . n 
D 1 245 LYS 245 264 264 LYS LYS D . n 
D 1 246 GLU 246 265 265 GLU GLU D . n 
D 1 247 THR 247 266 266 THR THR D . n 
D 1 248 MET 248 267 267 MET MET D . n 
D 1 249 LEU 249 268 268 LEU LEU D . n 
D 1 250 ARG 250 269 269 ARG ARG D . n 
D 1 251 ASP 251 270 270 ASP ASP D . n 
D 1 252 ILE 252 271 271 ILE ILE D . n 
D 1 253 LEU 253 272 272 LEU LEU D . n 
D 1 254 GLU 254 273 273 GLU GLU D . n 
D 1 255 MET 255 274 274 MET MET D . n 
D 1 256 GLN 256 275 275 GLN GLN D . n 
D 1 257 ARG 257 276 276 ARG ARG D . n 
D 1 258 ALA 258 277 277 ALA ALA D . n 
D 1 259 ALA 259 278 278 ALA ALA D . n 
D 1 260 LYS 260 279 279 LYS LYS D . n 
D 1 261 ALA 261 280 280 ALA ALA D . n 
D 1 262 GLY 262 281 281 GLY GLY D . n 
D 1 263 LYS 263 282 282 LYS LYS D . n 
D 1 264 ILE 264 283 283 ILE ILE D . n 
D 1 265 VAL 265 284 284 VAL VAL D . n 
D 1 266 VAL 266 285 285 VAL VAL D . n 
D 1 267 LEU 267 286 286 LEU LEU D . n 
D 1 268 LYS 268 287 287 LYS LYS D . n 
D 1 269 GLY 269 288 288 GLY GLY D . n 
D 1 270 TRP 270 289 289 TRP TRP D . n 
D 1 271 ALA 271 290 290 ALA ALA D . n 
D 1 272 GLY 272 291 291 GLY GLY D . n 
D 1 273 PHE 273 292 292 PHE PHE D . n 
D 1 274 THR 274 293 293 THR THR D . n 
D 1 275 PHE 275 294 294 PHE PHE D . n 
D 1 276 ILE 276 295 295 ILE ILE D . n 
D 1 277 ASP 277 296 296 ASP ASP D . n 
D 1 278 ASP 278 297 297 ASP ASP D . n 
D 1 279 GLN 279 298 298 GLN GLN D . n 
D 1 280 ALA 280 299 299 ALA ALA D . n 
D 1 281 MET 281 300 300 MET MET D . n 
D 1 282 ARG 282 301 301 ARG ARG D . n 
D 1 283 LYS 283 302 302 LYS LYS D . n 
D 1 284 PRO 284 303 303 PRO PRO D . n 
D 1 285 LEU 285 304 304 LEU LEU D . n 
D 1 286 THR 286 305 305 THR THR D . n 
D 1 287 GLN 287 306 306 GLN GLN D . n 
D 1 288 LYS 288 307 307 LYS LYS D . n 
D 1 289 ARG 289 308 308 ARG ARG D . n 
D 1 290 ARG 290 309 309 ARG ARG D . n 
D 1 291 VAL 291 310 310 VAL VAL D . n 
D 1 292 ALA 292 311 311 ALA ALA D . n 
D 1 293 LYS 293 312 312 LYS LYS D . n 
D 1 294 ASP 294 313 313 ASP ASP D . n 
D 1 295 SER 295 314 314 SER SER D . n 
D 1 296 LEU 296 315 315 LEU LEU D . n 
D 1 297 LYS 297 316 316 LYS LYS D . n 
D 1 298 PHE 298 317 317 PHE PHE D . n 
D 1 299 PRO 299 318 318 PRO PRO D . n 
D 1 300 LEU 300 319 319 LEU LEU D . n 
D 1 301 ALA 301 320 320 ALA ALA D . n 
D 1 302 CYS 302 321 321 CYS CYS D . n 
D 1 303 PHE 303 322 322 PHE PHE D . n 
D 1 304 LEU 304 323 323 LEU LEU D . n 
D 1 305 ALA 305 324 324 ALA ALA D . n 
D 1 306 GLY 306 325 325 GLY GLY D . n 
D 1 307 ALA 307 326 326 ALA ALA D . n 
D 1 308 GLN 308 327 327 GLN GLN D . n 
D 1 309 GLU 309 328 328 GLU GLU D . n 
D 1 310 ASN 310 329 329 ASN ASN D . n 
D 1 311 CYS 311 330 330 CYS CYS D . n 
D 1 312 TYR 312 331 331 TYR TYR D . n 
D 1 313 PHE 313 332 332 PHE PHE D . n 
D 1 314 ILE 314 333 333 ILE ILE D . n 
D 1 315 TYR 315 334 334 TYR TYR D . n 
D 1 316 ASN 316 335 335 ASN ASN D . n 
D 1 317 TRP 317 336 336 TRP TRP D . n 
D 1 318 GLY 318 337 337 GLY GLY D . n 
D 1 319 TYR 319 338 338 TYR TYR D . n 
D 1 320 ARG 320 339 339 ARG ARG D . n 
D 1 321 MET 321 340 340 MET MET D . n 
D 1 322 GLU 322 341 341 GLU GLU D . n 
D 1 323 ASN 323 342 342 ASN ASN D . n 
D 1 324 GLY 324 343 343 GLY GLY D . n 
D 1 325 CYS 325 344 344 CYS CYS D . n 
D 1 326 LEU 326 345 345 LEU LEU D . n 
D 1 327 GLU 327 346 346 GLU GLU D . n 
D 1 328 TRP 328 347 347 TRP TRP D . n 
D 1 329 TYR 329 348 348 TYR TYR D . n 
D 1 330 PRO 330 349 349 PRO PRO D . n 
D 1 331 GLU 331 350 350 GLU GLU D . n 
D 1 332 PHE 332 351 351 PHE PHE D . n 
D 1 333 ASP 333 352 352 ASP ASP D . n 
D 1 334 LYS 334 353 353 LYS LYS D . n 
D 1 335 PRO 335 354 354 PRO PRO D . n 
D 1 336 LEU 336 355 355 LEU LEU D . n 
D 1 337 GLY 337 356 356 GLY GLY D . n 
D 1 338 LYS 338 357 357 LYS LYS D . n 
D 1 339 PRO 339 358 358 PRO PRO D . n 
D 1 340 VAL 340 359 359 VAL VAL D . n 
D 1 341 GLY 341 360 360 GLY GLY D . n 
D 1 342 GLU 342 361 361 GLU GLU D . n 
D 1 343 MET 343 362 362 MET MET D . n 
D 1 344 VAL 344 363 363 VAL VAL D . n 
D 1 345 ARG 345 364 364 ARG ARG D . n 
D 1 346 ASP 346 365 365 ASP ASP D . n 
D 1 347 GLY 347 366 366 GLY GLY D . n 
D 1 348 TRP 348 367 367 TRP TRP D . n 
D 1 349 LYS 349 368 368 LYS LYS D . n 
D 1 350 LEU 350 369 369 LEU LEU D . n 
D 1 351 SER 351 370 370 SER SER D . n 
D 1 352 ARG 352 371 371 ARG ARG D . n 
D 1 353 GLU 353 372 372 GLU GLU D . n 
D 1 354 TYR 354 373 373 TYR TYR D . n 
D 1 355 LYS 355 374 374 LYS LYS D . n 
D 1 356 HIS 356 375 375 HIS HIS D . n 
D 1 357 ALA 357 376 376 ALA ALA D . n 
D 1 358 SER 358 377 377 SER SER D . n 
D 1 359 VAL 359 378 378 VAL VAL D . n 
D 1 360 ARG 360 379 379 ARG ARG D . n 
D 1 361 VAL 361 380 380 VAL VAL D . n 
D 1 362 ASP 362 381 381 ASP ASP D . n 
D 1 363 LEU 363 382 382 LEU LEU D . n 
D 1 364 GLU 364 383 383 GLU GLU D . n 
D 1 365 SER 365 384 384 SER SER D . n 
D 1 366 LYS 366 385 385 LYS LYS D . n 
D 1 367 GLU 367 386 386 GLU GLU D . n 
D 1 368 ALA 368 387 387 ALA ALA D . n 
D 1 369 GLU 369 388 388 GLU GLU D . n 
D 1 370 ILE 370 389 389 ILE ILE D . n 
D 1 371 ARG 371 390 390 ARG ARG D . n 
D 1 372 TRP 372 391 391 TRP TRP D . n 
D 1 373 ARG 373 392 392 ARG ARG D . n 
E 1 1   MET 1   20  ?   ?   ?   E . n 
E 1 2   HIS 2   21  ?   ?   ?   E . n 
E 1 3   HIS 3   22  ?   ?   ?   E . n 
E 1 4   HIS 4   23  ?   ?   ?   E . n 
E 1 5   HIS 5   24  ?   ?   ?   E . n 
E 1 6   HIS 6   25  ?   ?   ?   E . n 
E 1 7   HIS 7   26  ?   ?   ?   E . n 
E 1 8   GLU 8   27  ?   ?   ?   E . n 
E 1 9   ASN 9   28  ?   ?   ?   E . n 
E 1 10  LEU 10  29  ?   ?   ?   E . n 
E 1 11  TYR 11  30  ?   ?   ?   E . n 
E 1 12  PHE 12  31  ?   ?   ?   E . n 
E 1 13  GLN 13  32  ?   ?   ?   E . n 
E 1 14  GLY 14  33  ?   ?   ?   E . n 
E 1 15  SER 15  34  ?   ?   ?   E . n 
E 1 16  GLY 16  35  ?   ?   ?   E . n 
E 1 17  ASP 17  36  ?   ?   ?   E . n 
E 1 18  GLU 18  37  ?   ?   ?   E . n 
E 1 19  SER 19  38  38  SER SER E . n 
E 1 20  HIS 20  39  39  HIS HIS E . n 
E 1 21  TYR 21  40  40  TYR TYR E . n 
E 1 22  PRO 22  41  41  PRO PRO E . n 
E 1 23  GLU 23  42  42  GLU GLU E . n 
E 1 24  PHE 24  43  43  PHE PHE E . n 
E 1 25  SER 25  44  44  SER SER E . n 
E 1 26  TRP 26  45  45  TRP TRP E . n 
E 1 27  ASP 27  46  46  ASP ASP E . n 
E 1 28  THR 28  47  47  THR THR E . n 
E 1 29  VAL 29  48  48  VAL VAL E . n 
E 1 30  PRO 30  49  49  PRO PRO E . n 
E 1 31  ILE 31  50  50  ILE ILE E . n 
E 1 32  ALA 32  51  51  ALA ALA E . n 
E 1 33  PHE 33  52  52  PHE PHE E . n 
E 1 34  HIS 34  53  53  HIS HIS E . n 
E 1 35  PHE 35  54  54  PHE PHE E . n 
E 1 36  GLY 36  55  55  GLY GLY E . n 
E 1 37  LYS 37  56  56  LYS LYS E . n 
E 1 38  SER 38  57  57  SER SER E . n 
E 1 39  GLN 39  58  58  GLN GLN E . n 
E 1 40  GLY 40  59  59  GLY GLY E . n 
E 1 41  LEU 41  60  60  LEU LEU E . n 
E 1 42  LEU 42  61  61  LEU LEU E . n 
E 1 43  THR 43  62  62  THR THR E . n 
E 1 44  LYS 44  63  63  LYS LYS E . n 
E 1 45  GLU 45  64  64  GLU GLU E . n 
E 1 46  GLU 46  65  65  GLU GLU E . n 
E 1 47  ALA 47  66  66  ALA ALA E . n 
E 1 48  GLU 48  67  67  GLU GLU E . n 
E 1 49  PHE 49  68  68  PHE PHE E . n 
E 1 50  VAL 50  69  69  VAL VAL E . n 
E 1 51  ALA 51  70  70  ALA ALA E . n 
E 1 52  THR 52  71  71  THR THR E . n 
E 1 53  ARG 53  72  72  ARG ARG E . n 
E 1 54  SER 54  73  73  SER SER E . n 
E 1 55  ASN 55  74  74  ASN ASN E . n 
E 1 56  PHE 56  75  75  PHE PHE E . n 
E 1 57  ILE 57  76  76  ILE ILE E . n 
E 1 58  CYS 58  77  77  CYS CYS E . n 
E 1 59  LEU 59  78  78  LEU LEU E . n 
E 1 60  GLU 60  79  79  GLU GLU E . n 
E 1 61  LYS 61  80  80  LYS LYS E . n 
E 1 62  GLY 62  81  81  GLY GLY E . n 
E 1 63  HIS 63  82  82  HIS HIS E . n 
E 1 64  ALA 64  83  83  ALA ALA E . n 
E 1 65  THR 65  84  84  THR THR E . n 
E 1 66  ARG 66  85  85  ARG ARG E . n 
E 1 67  THR 67  86  86  THR THR E . n 
E 1 68  HIS 68  87  87  HIS HIS E . n 
E 1 69  GLY 69  88  88  GLY GLY E . n 
E 1 70  THR 70  89  89  THR THR E . n 
E 1 71  THR 71  90  90  THR THR E . n 
E 1 72  GLU 72  91  91  GLU GLU E . n 
E 1 73  ALA 73  92  92  ALA ALA E . n 
E 1 74  GLY 74  93  93  GLY GLY E . n 
E 1 75  ILE 75  94  94  ILE ILE E . n 
E 1 76  GLU 76  95  95  GLU GLU E . n 
E 1 77  ALA 77  96  96  ALA ALA E . n 
E 1 78  GLU 78  97  97  GLU GLU E . n 
E 1 79  ALA 79  98  98  ALA ALA E . n 
E 1 80  ARG 80  99  99  ARG ARG E . n 
E 1 81  GLN 81  100 100 GLN GLN E . n 
E 1 82  LEU 82  101 101 LEU LEU E . n 
E 1 83  LYS 83  102 102 LYS LYS E . n 
E 1 84  ASN 84  103 103 ASN ASN E . n 
E 1 85  LEU 85  104 104 LEU LEU E . n 
E 1 86  ASN 86  105 105 ASN ASN E . n 
E 1 87  PRO 87  106 106 PRO PRO E . n 
E 1 88  LYS 88  107 107 LYS LYS E . n 
E 1 89  MET 89  108 108 MET MET E . n 
E 1 90  LYS 90  109 109 LYS LYS E . n 
E 1 91  VAL 91  110 110 VAL VAL E . n 
E 1 92  ILE 92  111 111 ILE ILE E . n 
E 1 93  PHE 93  112 112 PHE PHE E . n 
E 1 94  TYR 94  113 113 TYR TYR E . n 
E 1 95  TRP 95  114 114 TRP TRP E . n 
E 1 96  ASN 96  115 115 ASN ASN E . n 
E 1 97  THR 97  116 116 THR THR E . n 
E 1 98  PHE 98  117 117 PHE PHE E . n 
E 1 99  LEU 99  118 118 LEU LEU E . n 
E 1 100 ASP 100 119 119 ASP ASP E . n 
E 1 101 TYR 101 120 120 TYR TYR E . n 
E 1 102 SER 102 121 121 SER SER E . n 
E 1 103 MET 103 122 122 MET MET E . n 
E 1 104 PHE 104 123 123 PHE PHE E . n 
E 1 105 ALA 105 124 124 ALA ALA E . n 
E 1 106 ALA 106 125 125 ALA ALA E . n 
E 1 107 HIS 107 126 126 HIS HIS E . n 
E 1 108 LYS 108 127 127 LYS LYS E . n 
E 1 109 GLU 109 128 128 GLU GLU E . n 
E 1 110 TYR 110 129 129 TYR TYR E . n 
E 1 111 ALA 111 130 130 ALA ALA E . n 
E 1 112 LYS 112 131 131 LYS LYS E . n 
E 1 113 HIS 113 132 132 HIS HIS E . n 
E 1 114 PRO 114 133 133 PRO PRO E . n 
E 1 115 GLN 115 134 134 GLN GLN E . n 
E 1 116 TRP 116 135 135 TRP TRP E . n 
E 1 117 TRP 117 136 136 TRP TRP E . n 
E 1 118 LEU 118 137 137 LEU LEU E . n 
E 1 119 ARG 119 138 138 ARG ARG E . n 
E 1 120 THR 120 139 139 THR THR E . n 
E 1 121 THR 121 140 140 THR THR E . n 
E 1 122 THR 122 141 141 THR THR E . n 
E 1 123 GLY 123 142 142 GLY GLY E . n 
E 1 124 GLU 124 143 143 GLU GLU E . n 
E 1 125 LEU 125 144 144 LEU LEU E . n 
E 1 126 ASP 126 145 145 ASP ASP E . n 
E 1 127 ARG 127 146 146 ARG ARG E . n 
E 1 128 LYS 128 147 147 LYS LYS E . n 
E 1 129 LYS 129 148 148 LYS LYS E . n 
E 1 130 GLY 130 149 149 GLY GLY E . n 
E 1 131 GLN 131 150 150 GLN GLN E . n 
E 1 132 LEU 132 151 151 LEU LEU E . n 
E 1 133 MET 133 152 152 MET MET E . n 
E 1 134 ARG 134 153 153 ARG ARG E . n 
E 1 135 TYR 135 154 154 TYR TYR E . n 
E 1 136 ASP 136 155 155 ASP ASP E . n 
E 1 137 LEU 137 156 156 LEU LEU E . n 
E 1 138 SER 138 157 157 SER SER E . n 
E 1 139 ASN 139 158 158 ASN ASN E . n 
E 1 140 ALA 140 159 159 ALA ALA E . n 
E 1 141 GLU 141 160 160 GLU GLU E . n 
E 1 142 PHE 142 161 161 PHE PHE E . n 
E 1 143 ARG 143 162 162 ARG ARG E . n 
E 1 144 ASN 144 163 163 ASN ASN E . n 
E 1 145 TRP 145 164 164 TRP TRP E . n 
E 1 146 TRP 146 165 165 TRP TRP E . n 
E 1 147 THR 147 166 166 THR THR E . n 
E 1 148 ASN 148 167 167 ASN ASN E . n 
E 1 149 VAL 149 168 168 VAL VAL E . n 
E 1 150 ALA 150 169 169 ALA ALA E . n 
E 1 151 ALA 151 170 170 ALA ALA E . n 
E 1 152 LYS 152 171 171 LYS LYS E . n 
E 1 153 ALA 153 172 172 ALA ALA E . n 
E 1 154 VAL 154 173 173 VAL VAL E . n 
E 1 155 VAL 155 174 174 VAL VAL E . n 
E 1 156 ASP 156 175 175 ASP ASP E . n 
E 1 157 GLY 157 176 176 GLY GLY E . n 
E 1 158 THR 158 177 177 THR THR E . n 
E 1 159 CYS 159 178 178 CYS CYS E . n 
E 1 160 ASP 160 179 179 ASP ASP E . n 
E 1 161 GLY 161 180 180 GLY GLY E . n 
E 1 162 VAL 162 181 181 VAL VAL E . n 
E 1 163 PHE 163 182 182 PHE PHE E . n 
E 1 164 MET 164 183 183 MET MET E . n 
E 1 165 ASP 165 184 184 ASP ASP E . n 
E 1 166 ALA 166 185 185 ALA ALA E . n 
E 1 167 PHE 167 186 186 PHE PHE E . n 
E 1 168 PRO 168 187 187 PRO PRO E . n 
E 1 169 GLN 169 188 188 GLN GLN E . n 
E 1 170 ILE 170 189 189 ILE ILE E . n 
E 1 171 ALA 171 190 190 ALA ALA E . n 
E 1 172 SER 172 191 191 SER SER E . n 
E 1 173 GLN 173 192 192 GLN GLN E . n 
E 1 174 ALA 174 193 193 ALA ALA E . n 
E 1 175 ASN 175 194 194 ASN ASN E . n 
E 1 176 ARG 176 195 195 ARG ARG E . n 
E 1 177 LYS 177 196 196 LYS LYS E . n 
E 1 178 LEU 178 197 197 LEU LEU E . n 
E 1 179 TRP 179 198 198 TRP TRP E . n 
E 1 180 GLY 180 199 199 GLY GLY E . n 
E 1 181 ASP 181 200 200 ASP ASP E . n 
E 1 182 GLU 182 201 201 GLU GLU E . n 
E 1 183 LYS 183 202 202 LYS LYS E . n 
E 1 184 PHE 184 203 203 PHE PHE E . n 
E 1 185 GLU 185 204 204 GLU GLU E . n 
E 1 186 ALA 186 205 205 ALA ALA E . n 
E 1 187 ILE 187 206 206 ILE ILE E . n 
E 1 188 GLN 188 207 207 GLN GLN E . n 
E 1 189 GLN 189 208 208 GLN GLN E . n 
E 1 190 GLY 190 209 209 GLY GLY E . n 
E 1 191 LEU 191 210 210 LEU LEU E . n 
E 1 192 GLN 192 211 211 GLN GLN E . n 
E 1 193 ASP 193 212 212 ASP ASP E . n 
E 1 194 ILE 194 213 213 ILE ILE E . n 
E 1 195 ILE 195 214 214 ILE ILE E . n 
E 1 196 GLN 196 215 215 GLN GLN E . n 
E 1 197 GLU 197 216 216 GLU GLU E . n 
E 1 198 THR 198 217 217 THR THR E . n 
E 1 199 ARG 199 218 218 ARG ARG E . n 
E 1 200 GLN 200 219 219 GLN GLN E . n 
E 1 201 LYS 201 220 220 LYS LYS E . n 
E 1 202 ILE 202 221 221 ILE ILE E . n 
E 1 203 GLY 203 222 222 GLY GLY E . n 
E 1 204 ASP 204 223 223 ASP ASP E . n 
E 1 205 ASP 205 224 224 ASP ASP E . n 
E 1 206 LYS 206 225 225 LYS LYS E . n 
E 1 207 LEU 207 226 226 LEU LEU E . n 
E 1 208 ILE 208 227 227 ILE ILE E . n 
E 1 209 VAL 209 228 228 VAL VAL E . n 
E 1 210 TYR 210 229 229 TYR TYR E . n 
E 1 211 ASN 211 230 230 ASN ASN E . n 
E 1 212 GLY 212 231 231 GLY GLY E . n 
E 1 213 ILE 213 232 232 ILE ILE E . n 
E 1 214 ARG 214 233 233 ARG ARG E . n 
E 1 215 SER 215 234 234 SER SER E . n 
E 1 216 THR 216 235 235 THR THR E . n 
E 1 217 PRO 217 236 236 PRO PRO E . n 
E 1 218 ASP 218 237 237 ASP ASP E . n 
E 1 219 TRP 219 238 238 TRP TRP E . n 
E 1 220 SER 220 239 239 SER SER E . n 
E 1 221 ALA 221 240 240 ALA ALA E . n 
E 1 222 GLY 222 241 241 GLY GLY E . n 
E 1 223 PHE 223 242 242 PHE PHE E . n 
E 1 224 ASP 224 243 243 ASP ASP E . n 
E 1 225 PHE 225 244 244 PHE PHE E . n 
E 1 226 ALA 226 245 245 ALA ALA E . n 
E 1 227 GLU 227 246 246 GLU GLU E . n 
E 1 228 TYR 228 247 247 TYR TYR E . n 
E 1 229 THR 229 248 248 THR THR E . n 
E 1 230 ASP 230 249 249 ASP ASP E . n 
E 1 231 ALA 231 250 250 ALA ALA E . n 
E 1 232 ALA 232 251 251 ALA ALA E . n 
E 1 233 MET 233 252 252 MET MET E . n 
E 1 234 ILE 234 253 253 ILE ILE E . n 
E 1 235 GLU 235 254 254 GLU GLU E . n 
E 1 236 HIS 236 255 255 HIS HIS E . n 
E 1 237 PHE 237 256 256 PHE PHE E . n 
E 1 238 GLY 238 257 257 GLY GLY E . n 
E 1 239 HIS 239 258 258 HIS HIS E . n 
E 1 240 PHE 240 259 259 PHE PHE E . n 
E 1 241 GLN 241 260 260 GLN GLN E . n 
E 1 242 SER 242 261 261 SER SER E . n 
E 1 243 ALA 243 262 262 ALA ALA E . n 
E 1 244 SER 244 263 263 SER SER E . n 
E 1 245 LYS 245 264 264 LYS LYS E . n 
E 1 246 GLU 246 265 265 GLU GLU E . n 
E 1 247 THR 247 266 266 THR THR E . n 
E 1 248 MET 248 267 267 MET MET E . n 
E 1 249 LEU 249 268 268 LEU LEU E . n 
E 1 250 ARG 250 269 269 ARG ARG E . n 
E 1 251 ASP 251 270 270 ASP ASP E . n 
E 1 252 ILE 252 271 271 ILE ILE E . n 
E 1 253 LEU 253 272 272 LEU LEU E . n 
E 1 254 GLU 254 273 273 GLU GLU E . n 
E 1 255 MET 255 274 274 MET MET E . n 
E 1 256 GLN 256 275 275 GLN GLN E . n 
E 1 257 ARG 257 276 276 ARG ARG E . n 
E 1 258 ALA 258 277 277 ALA ALA E . n 
E 1 259 ALA 259 278 278 ALA ALA E . n 
E 1 260 LYS 260 279 279 LYS LYS E . n 
E 1 261 ALA 261 280 280 ALA ALA E . n 
E 1 262 GLY 262 281 281 GLY GLY E . n 
E 1 263 LYS 263 282 282 LYS LYS E . n 
E 1 264 ILE 264 283 283 ILE ILE E . n 
E 1 265 VAL 265 284 284 VAL VAL E . n 
E 1 266 VAL 266 285 285 VAL VAL E . n 
E 1 267 LEU 267 286 286 LEU LEU E . n 
E 1 268 LYS 268 287 287 LYS LYS E . n 
E 1 269 GLY 269 288 288 GLY GLY E . n 
E 1 270 TRP 270 289 289 TRP TRP E . n 
E 1 271 ALA 271 290 290 ALA ALA E . n 
E 1 272 GLY 272 291 291 GLY GLY E . n 
E 1 273 PHE 273 292 292 PHE PHE E . n 
E 1 274 THR 274 293 293 THR THR E . n 
E 1 275 PHE 275 294 294 PHE PHE E . n 
E 1 276 ILE 276 295 295 ILE ILE E . n 
E 1 277 ASP 277 296 296 ASP ASP E . n 
E 1 278 ASP 278 297 297 ASP ALA E . n 
E 1 279 GLN 279 298 298 GLN GLN E . n 
E 1 280 ALA 280 299 299 ALA ALA E . n 
E 1 281 MET 281 300 300 MET MET E . n 
E 1 282 ARG 282 301 301 ARG ARG E . n 
E 1 283 LYS 283 302 302 LYS LYS E . n 
E 1 284 PRO 284 303 303 PRO PRO E . n 
E 1 285 LEU 285 304 304 LEU LEU E . n 
E 1 286 THR 286 305 305 THR THR E . n 
E 1 287 GLN 287 306 306 GLN GLN E . n 
E 1 288 LYS 288 307 307 LYS LYS E . n 
E 1 289 ARG 289 308 308 ARG ARG E . n 
E 1 290 ARG 290 309 309 ARG ARG E . n 
E 1 291 VAL 291 310 310 VAL VAL E . n 
E 1 292 ALA 292 311 311 ALA ALA E . n 
E 1 293 LYS 293 312 312 LYS LYS E . n 
E 1 294 ASP 294 313 313 ASP ASP E . n 
E 1 295 SER 295 314 314 SER SER E . n 
E 1 296 LEU 296 315 315 LEU LEU E . n 
E 1 297 LYS 297 316 316 LYS LYS E . n 
E 1 298 PHE 298 317 317 PHE PHE E . n 
E 1 299 PRO 299 318 318 PRO PRO E . n 
E 1 300 LEU 300 319 319 LEU LEU E . n 
E 1 301 ALA 301 320 320 ALA ALA E . n 
E 1 302 CYS 302 321 321 CYS CYS E . n 
E 1 303 PHE 303 322 322 PHE PHE E . n 
E 1 304 LEU 304 323 323 LEU LEU E . n 
E 1 305 ALA 305 324 324 ALA ALA E . n 
E 1 306 GLY 306 325 325 GLY GLY E . n 
E 1 307 ALA 307 326 326 ALA ALA E . n 
E 1 308 GLN 308 327 327 GLN GLN E . n 
E 1 309 GLU 309 328 328 GLU GLU E . n 
E 1 310 ASN 310 329 329 ASN ASN E . n 
E 1 311 CYS 311 330 330 CYS CYS E . n 
E 1 312 TYR 312 331 331 TYR TYR E . n 
E 1 313 PHE 313 332 332 PHE PHE E . n 
E 1 314 ILE 314 333 333 ILE ILE E . n 
E 1 315 TYR 315 334 334 TYR TYR E . n 
E 1 316 ASN 316 335 335 ASN ASN E . n 
E 1 317 TRP 317 336 336 TRP TRP E . n 
E 1 318 GLY 318 337 337 GLY GLY E . n 
E 1 319 TYR 319 338 338 TYR TYR E . n 
E 1 320 ARG 320 339 339 ARG ARG E . n 
E 1 321 MET 321 340 340 MET MET E . n 
E 1 322 GLU 322 341 341 GLU GLU E . n 
E 1 323 ASN 323 342 342 ASN ASN E . n 
E 1 324 GLY 324 343 343 GLY GLY E . n 
E 1 325 CYS 325 344 344 CYS CYS E . n 
E 1 326 LEU 326 345 345 LEU LEU E . n 
E 1 327 GLU 327 346 346 GLU GLU E . n 
E 1 328 TRP 328 347 347 TRP TRP E . n 
E 1 329 TYR 329 348 348 TYR TYR E . n 
E 1 330 PRO 330 349 349 PRO PRO E . n 
E 1 331 GLU 331 350 350 GLU GLU E . n 
E 1 332 PHE 332 351 351 PHE PHE E . n 
E 1 333 ASP 333 352 352 ASP ASP E . n 
E 1 334 LYS 334 353 353 LYS LYS E . n 
E 1 335 PRO 335 354 354 PRO PRO E . n 
E 1 336 LEU 336 355 355 LEU LEU E . n 
E 1 337 GLY 337 356 356 GLY GLY E . n 
E 1 338 LYS 338 357 357 LYS LYS E . n 
E 1 339 PRO 339 358 358 PRO PRO E . n 
E 1 340 VAL 340 359 359 VAL VAL E . n 
E 1 341 GLY 341 360 360 GLY GLY E . n 
E 1 342 GLU 342 361 361 GLU GLU E . n 
E 1 343 MET 343 362 362 MET MET E . n 
E 1 344 VAL 344 363 363 VAL VAL E . n 
E 1 345 ARG 345 364 364 ARG ARG E . n 
E 1 346 ASP 346 365 365 ASP ASP E . n 
E 1 347 GLY 347 366 366 GLY GLY E . n 
E 1 348 TRP 348 367 367 TRP TRP E . n 
E 1 349 LYS 349 368 368 LYS LYS E . n 
E 1 350 LEU 350 369 369 LEU LEU E . n 
E 1 351 SER 351 370 370 SER SER E . n 
E 1 352 ARG 352 371 371 ARG ARG E . n 
E 1 353 GLU 353 372 372 GLU GLU E . n 
E 1 354 TYR 354 373 373 TYR TYR E . n 
E 1 355 LYS 355 374 374 LYS LYS E . n 
E 1 356 HIS 356 375 375 HIS HIS E . n 
E 1 357 ALA 357 376 376 ALA ALA E . n 
E 1 358 SER 358 377 377 SER SER E . n 
E 1 359 VAL 359 378 378 VAL VAL E . n 
E 1 360 ARG 360 379 379 ARG ARG E . n 
E 1 361 VAL 361 380 380 VAL VAL E . n 
E 1 362 ASP 362 381 381 ASP ASP E . n 
E 1 363 LEU 363 382 382 LEU LEU E . n 
E 1 364 GLU 364 383 383 GLU GLU E . n 
E 1 365 SER 365 384 384 SER SER E . n 
E 1 366 LYS 366 385 385 LYS LYS E . n 
E 1 367 GLU 367 386 386 GLU GLU E . n 
E 1 368 ALA 368 387 387 ALA ALA E . n 
E 1 369 GLU 369 388 388 GLU GLU E . n 
E 1 370 ILE 370 389 389 ILE ILE E . n 
E 1 371 ARG 371 390 390 ARG ARG E . n 
E 1 372 TRP 372 391 391 TRP TRP E . n 
E 1 373 ARG 373 392 392 ARG ARG E . n 
F 1 1   MET 1   20  ?   ?   ?   F . n 
F 1 2   HIS 2   21  ?   ?   ?   F . n 
F 1 3   HIS 3   22  ?   ?   ?   F . n 
F 1 4   HIS 4   23  ?   ?   ?   F . n 
F 1 5   HIS 5   24  ?   ?   ?   F . n 
F 1 6   HIS 6   25  ?   ?   ?   F . n 
F 1 7   HIS 7   26  ?   ?   ?   F . n 
F 1 8   GLU 8   27  ?   ?   ?   F . n 
F 1 9   ASN 9   28  ?   ?   ?   F . n 
F 1 10  LEU 10  29  ?   ?   ?   F . n 
F 1 11  TYR 11  30  ?   ?   ?   F . n 
F 1 12  PHE 12  31  ?   ?   ?   F . n 
F 1 13  GLN 13  32  ?   ?   ?   F . n 
F 1 14  GLY 14  33  ?   ?   ?   F . n 
F 1 15  SER 15  34  ?   ?   ?   F . n 
F 1 16  GLY 16  35  ?   ?   ?   F . n 
F 1 17  ASP 17  36  ?   ?   ?   F . n 
F 1 18  GLU 18  37  37  GLU GLU F . n 
F 1 19  SER 19  38  38  SER SER F . n 
F 1 20  HIS 20  39  39  HIS HIS F . n 
F 1 21  TYR 21  40  40  TYR TYR F . n 
F 1 22  PRO 22  41  41  PRO PRO F . n 
F 1 23  GLU 23  42  42  GLU GLU F . n 
F 1 24  PHE 24  43  43  PHE PHE F . n 
F 1 25  SER 25  44  44  SER SER F . n 
F 1 26  TRP 26  45  45  TRP TRP F . n 
F 1 27  ASP 27  46  46  ASP ASP F . n 
F 1 28  THR 28  47  47  THR THR F . n 
F 1 29  VAL 29  48  48  VAL VAL F . n 
F 1 30  PRO 30  49  49  PRO PRO F . n 
F 1 31  ILE 31  50  50  ILE ILE F . n 
F 1 32  ALA 32  51  51  ALA ALA F . n 
F 1 33  PHE 33  52  52  PHE PHE F . n 
F 1 34  HIS 34  53  53  HIS HIS F . n 
F 1 35  PHE 35  54  54  PHE PHE F . n 
F 1 36  GLY 36  55  55  GLY GLY F . n 
F 1 37  LYS 37  56  56  LYS LYS F . n 
F 1 38  SER 38  57  57  SER SER F . n 
F 1 39  GLN 39  58  58  GLN GLN F . n 
F 1 40  GLY 40  59  59  GLY GLY F . n 
F 1 41  LEU 41  60  60  LEU LEU F . n 
F 1 42  LEU 42  61  61  LEU LEU F . n 
F 1 43  THR 43  62  62  THR THR F . n 
F 1 44  LYS 44  63  63  LYS LYS F . n 
F 1 45  GLU 45  64  64  GLU GLU F . n 
F 1 46  GLU 46  65  65  GLU GLU F . n 
F 1 47  ALA 47  66  66  ALA ALA F . n 
F 1 48  GLU 48  67  67  GLU GLU F . n 
F 1 49  PHE 49  68  68  PHE PHE F . n 
F 1 50  VAL 50  69  69  VAL VAL F . n 
F 1 51  ALA 51  70  70  ALA ALA F . n 
F 1 52  THR 52  71  71  THR THR F . n 
F 1 53  ARG 53  72  72  ARG ARG F . n 
F 1 54  SER 54  73  73  SER SER F . n 
F 1 55  ASN 55  74  74  ASN ASN F . n 
F 1 56  PHE 56  75  75  PHE PHE F . n 
F 1 57  ILE 57  76  76  ILE ILE F . n 
F 1 58  CYS 58  77  77  CYS CYS F . n 
F 1 59  LEU 59  78  78  LEU LEU F . n 
F 1 60  GLU 60  79  79  GLU GLU F . n 
F 1 61  LYS 61  80  80  LYS LYS F . n 
F 1 62  GLY 62  81  81  GLY GLY F . n 
F 1 63  HIS 63  82  82  HIS HIS F . n 
F 1 64  ALA 64  83  83  ALA ALA F . n 
F 1 65  THR 65  84  84  THR THR F . n 
F 1 66  ARG 66  85  85  ARG ARG F . n 
F 1 67  THR 67  86  86  THR THR F . n 
F 1 68  HIS 68  87  87  HIS HIS F . n 
F 1 69  GLY 69  88  88  GLY GLY F . n 
F 1 70  THR 70  89  89  THR THR F . n 
F 1 71  THR 71  90  90  THR THR F . n 
F 1 72  GLU 72  91  91  GLU GLU F . n 
F 1 73  ALA 73  92  92  ALA ALA F . n 
F 1 74  GLY 74  93  93  GLY GLY F . n 
F 1 75  ILE 75  94  94  ILE ILE F . n 
F 1 76  GLU 76  95  95  GLU GLU F . n 
F 1 77  ALA 77  96  96  ALA ALA F . n 
F 1 78  GLU 78  97  97  GLU GLU F . n 
F 1 79  ALA 79  98  98  ALA ALA F . n 
F 1 80  ARG 80  99  99  ARG ARG F . n 
F 1 81  GLN 81  100 100 GLN GLN F . n 
F 1 82  LEU 82  101 101 LEU LEU F . n 
F 1 83  LYS 83  102 102 LYS LYS F . n 
F 1 84  ASN 84  103 103 ASN ASN F . n 
F 1 85  LEU 85  104 104 LEU LEU F . n 
F 1 86  ASN 86  105 105 ASN ASN F . n 
F 1 87  PRO 87  106 106 PRO PRO F . n 
F 1 88  LYS 88  107 107 LYS LYS F . n 
F 1 89  MET 89  108 108 MET MET F . n 
F 1 90  LYS 90  109 109 LYS LYS F . n 
F 1 91  VAL 91  110 110 VAL VAL F . n 
F 1 92  ILE 92  111 111 ILE ILE F . n 
F 1 93  PHE 93  112 112 PHE PHE F . n 
F 1 94  TYR 94  113 113 TYR TYR F . n 
F 1 95  TRP 95  114 114 TRP TRP F . n 
F 1 96  ASN 96  115 115 ASN ASN F . n 
F 1 97  THR 97  116 116 THR THR F . n 
F 1 98  PHE 98  117 117 PHE PHE F . n 
F 1 99  LEU 99  118 118 LEU LEU F . n 
F 1 100 ASP 100 119 119 ASP ASP F . n 
F 1 101 TYR 101 120 120 TYR TYR F . n 
F 1 102 SER 102 121 121 SER SER F . n 
F 1 103 MET 103 122 122 MET MET F . n 
F 1 104 PHE 104 123 123 PHE PHE F . n 
F 1 105 ALA 105 124 124 ALA ALA F . n 
F 1 106 ALA 106 125 125 ALA ALA F . n 
F 1 107 HIS 107 126 126 HIS HIS F . n 
F 1 108 LYS 108 127 127 LYS LYS F . n 
F 1 109 GLU 109 128 128 GLU GLU F . n 
F 1 110 TYR 110 129 129 TYR TYR F . n 
F 1 111 ALA 111 130 130 ALA ALA F . n 
F 1 112 LYS 112 131 131 LYS LYS F . n 
F 1 113 HIS 113 132 132 HIS HIS F . n 
F 1 114 PRO 114 133 133 PRO PRO F . n 
F 1 115 GLN 115 134 134 GLN GLN F . n 
F 1 116 TRP 116 135 135 TRP TRP F . n 
F 1 117 TRP 117 136 136 TRP TRP F . n 
F 1 118 LEU 118 137 137 LEU LEU F . n 
F 1 119 ARG 119 138 138 ARG ARG F . n 
F 1 120 THR 120 139 139 THR THR F . n 
F 1 121 THR 121 140 140 THR THR F . n 
F 1 122 THR 122 141 141 THR THR F . n 
F 1 123 GLY 123 142 142 GLY GLY F . n 
F 1 124 GLU 124 143 143 GLU GLU F . n 
F 1 125 LEU 125 144 144 LEU LEU F . n 
F 1 126 ASP 126 145 145 ASP ASP F . n 
F 1 127 ARG 127 146 146 ARG ARG F . n 
F 1 128 LYS 128 147 147 LYS LYS F . n 
F 1 129 LYS 129 148 148 LYS LYS F . n 
F 1 130 GLY 130 149 149 GLY GLY F . n 
F 1 131 GLN 131 150 150 GLN GLN F . n 
F 1 132 LEU 132 151 151 LEU LEU F . n 
F 1 133 MET 133 152 152 MET MET F . n 
F 1 134 ARG 134 153 153 ARG ARG F . n 
F 1 135 TYR 135 154 154 TYR TYR F . n 
F 1 136 ASP 136 155 155 ASP ASP F . n 
F 1 137 LEU 137 156 156 LEU LEU F . n 
F 1 138 SER 138 157 157 SER SER F . n 
F 1 139 ASN 139 158 158 ASN ASN F . n 
F 1 140 ALA 140 159 159 ALA ALA F . n 
F 1 141 GLU 141 160 160 GLU GLU F . n 
F 1 142 PHE 142 161 161 PHE PHE F . n 
F 1 143 ARG 143 162 162 ARG ARG F . n 
F 1 144 ASN 144 163 163 ASN ASN F . n 
F 1 145 TRP 145 164 164 TRP TRP F . n 
F 1 146 TRP 146 165 165 TRP TRP F . n 
F 1 147 THR 147 166 166 THR THR F . n 
F 1 148 ASN 148 167 167 ASN ASN F . n 
F 1 149 VAL 149 168 168 VAL VAL F . n 
F 1 150 ALA 150 169 169 ALA ALA F . n 
F 1 151 ALA 151 170 170 ALA ALA F . n 
F 1 152 LYS 152 171 171 LYS LYS F . n 
F 1 153 ALA 153 172 172 ALA ALA F . n 
F 1 154 VAL 154 173 173 VAL VAL F . n 
F 1 155 VAL 155 174 174 VAL VAL F . n 
F 1 156 ASP 156 175 175 ASP ASP F . n 
F 1 157 GLY 157 176 176 GLY GLY F . n 
F 1 158 THR 158 177 177 THR THR F . n 
F 1 159 CYS 159 178 178 CYS CYS F . n 
F 1 160 ASP 160 179 179 ASP ASP F . n 
F 1 161 GLY 161 180 180 GLY GLY F . n 
F 1 162 VAL 162 181 181 VAL VAL F . n 
F 1 163 PHE 163 182 182 PHE PHE F . n 
F 1 164 MET 164 183 183 MET MET F . n 
F 1 165 ASP 165 184 184 ASP ASP F . n 
F 1 166 ALA 166 185 185 ALA ALA F . n 
F 1 167 PHE 167 186 186 PHE PHE F . n 
F 1 168 PRO 168 187 187 PRO PRO F . n 
F 1 169 GLN 169 188 188 GLN GLN F . n 
F 1 170 ILE 170 189 189 ILE ILE F . n 
F 1 171 ALA 171 190 190 ALA ALA F . n 
F 1 172 SER 172 191 191 SER SER F . n 
F 1 173 GLN 173 192 192 GLN GLN F . n 
F 1 174 ALA 174 193 193 ALA ALA F . n 
F 1 175 ASN 175 194 194 ASN ASN F . n 
F 1 176 ARG 176 195 195 ARG ARG F . n 
F 1 177 LYS 177 196 196 LYS LYS F . n 
F 1 178 LEU 178 197 197 LEU LEU F . n 
F 1 179 TRP 179 198 198 TRP TRP F . n 
F 1 180 GLY 180 199 199 GLY GLY F . n 
F 1 181 ASP 181 200 200 ASP ASP F . n 
F 1 182 GLU 182 201 201 GLU GLU F . n 
F 1 183 LYS 183 202 202 LYS LYS F . n 
F 1 184 PHE 184 203 203 PHE PHE F . n 
F 1 185 GLU 185 204 204 GLU GLU F . n 
F 1 186 ALA 186 205 205 ALA ALA F . n 
F 1 187 ILE 187 206 206 ILE ILE F . n 
F 1 188 GLN 188 207 207 GLN GLN F . n 
F 1 189 GLN 189 208 208 GLN GLN F . n 
F 1 190 GLY 190 209 209 GLY GLY F . n 
F 1 191 LEU 191 210 210 LEU LEU F . n 
F 1 192 GLN 192 211 211 GLN GLN F . n 
F 1 193 ASP 193 212 212 ASP ASP F . n 
F 1 194 ILE 194 213 213 ILE ILE F . n 
F 1 195 ILE 195 214 214 ILE ILE F . n 
F 1 196 GLN 196 215 215 GLN GLN F . n 
F 1 197 GLU 197 216 216 GLU GLU F . n 
F 1 198 THR 198 217 217 THR THR F . n 
F 1 199 ARG 199 218 218 ARG ARG F . n 
F 1 200 GLN 200 219 219 GLN GLN F . n 
F 1 201 LYS 201 220 220 LYS LYS F . n 
F 1 202 ILE 202 221 221 ILE ILE F . n 
F 1 203 GLY 203 222 222 GLY GLY F . n 
F 1 204 ASP 204 223 223 ASP ASP F . n 
F 1 205 ASP 205 224 224 ASP ASP F . n 
F 1 206 LYS 206 225 225 LYS LYS F . n 
F 1 207 LEU 207 226 226 LEU LEU F . n 
F 1 208 ILE 208 227 227 ILE ILE F . n 
F 1 209 VAL 209 228 228 VAL VAL F . n 
F 1 210 TYR 210 229 229 TYR TYR F . n 
F 1 211 ASN 211 230 230 ASN ASN F . n 
F 1 212 GLY 212 231 231 GLY GLY F . n 
F 1 213 ILE 213 232 232 ILE ILE F . n 
F 1 214 ARG 214 233 233 ARG ARG F . n 
F 1 215 SER 215 234 234 SER SER F . n 
F 1 216 THR 216 235 235 THR THR F . n 
F 1 217 PRO 217 236 236 PRO PRO F . n 
F 1 218 ASP 218 237 237 ASP ASP F . n 
F 1 219 TRP 219 238 238 TRP TRP F . n 
F 1 220 SER 220 239 239 SER SER F . n 
F 1 221 ALA 221 240 240 ALA ALA F . n 
F 1 222 GLY 222 241 241 GLY GLY F . n 
F 1 223 PHE 223 242 242 PHE PHE F . n 
F 1 224 ASP 224 243 243 ASP ASP F . n 
F 1 225 PHE 225 244 244 PHE PHE F . n 
F 1 226 ALA 226 245 245 ALA ALA F . n 
F 1 227 GLU 227 246 246 GLU GLU F . n 
F 1 228 TYR 228 247 247 TYR TYR F . n 
F 1 229 THR 229 248 248 THR THR F . n 
F 1 230 ASP 230 249 249 ASP ASP F . n 
F 1 231 ALA 231 250 250 ALA ALA F . n 
F 1 232 ALA 232 251 251 ALA ALA F . n 
F 1 233 MET 233 252 252 MET MET F . n 
F 1 234 ILE 234 253 253 ILE ILE F . n 
F 1 235 GLU 235 254 254 GLU GLU F . n 
F 1 236 HIS 236 255 255 HIS HIS F . n 
F 1 237 PHE 237 256 256 PHE PHE F . n 
F 1 238 GLY 238 257 257 GLY GLY F . n 
F 1 239 HIS 239 258 258 HIS HIS F . n 
F 1 240 PHE 240 259 259 PHE PHE F . n 
F 1 241 GLN 241 260 260 GLN GLN F . n 
F 1 242 SER 242 261 261 SER SER F . n 
F 1 243 ALA 243 262 262 ALA ALA F . n 
F 1 244 SER 244 263 263 SER SER F . n 
F 1 245 LYS 245 264 264 LYS LYS F . n 
F 1 246 GLU 246 265 265 GLU GLU F . n 
F 1 247 THR 247 266 266 THR THR F . n 
F 1 248 MET 248 267 267 MET MET F . n 
F 1 249 LEU 249 268 268 LEU LEU F . n 
F 1 250 ARG 250 269 269 ARG ARG F . n 
F 1 251 ASP 251 270 270 ASP ASP F . n 
F 1 252 ILE 252 271 271 ILE ILE F . n 
F 1 253 LEU 253 272 272 LEU LEU F . n 
F 1 254 GLU 254 273 273 GLU GLU F . n 
F 1 255 MET 255 274 274 MET MET F . n 
F 1 256 GLN 256 275 275 GLN GLN F . n 
F 1 257 ARG 257 276 276 ARG ARG F . n 
F 1 258 ALA 258 277 277 ALA ALA F . n 
F 1 259 ALA 259 278 278 ALA ALA F . n 
F 1 260 LYS 260 279 279 LYS LYS F . n 
F 1 261 ALA 261 280 280 ALA ALA F . n 
F 1 262 GLY 262 281 281 GLY GLY F . n 
F 1 263 LYS 263 282 282 LYS LYS F . n 
F 1 264 ILE 264 283 283 ILE ILE F . n 
F 1 265 VAL 265 284 284 VAL VAL F . n 
F 1 266 VAL 266 285 285 VAL VAL F . n 
F 1 267 LEU 267 286 286 LEU LEU F . n 
F 1 268 LYS 268 287 287 LYS LYS F . n 
F 1 269 GLY 269 288 288 GLY GLY F . n 
F 1 270 TRP 270 289 289 TRP TRP F . n 
F 1 271 ALA 271 290 290 ALA ALA F . n 
F 1 272 GLY 272 291 291 GLY GLY F . n 
F 1 273 PHE 273 292 292 PHE PHE F . n 
F 1 274 THR 274 293 293 THR THR F . n 
F 1 275 PHE 275 294 294 PHE PHE F . n 
F 1 276 ILE 276 295 295 ILE ILE F . n 
F 1 277 ASP 277 296 296 ASP ASP F . n 
F 1 278 ASP 278 297 297 ASP ASP F . n 
F 1 279 GLN 279 298 298 GLN GLN F . n 
F 1 280 ALA 280 299 299 ALA ALA F . n 
F 1 281 MET 281 300 300 MET MET F . n 
F 1 282 ARG 282 301 301 ARG ARG F . n 
F 1 283 LYS 283 302 302 LYS LYS F . n 
F 1 284 PRO 284 303 303 PRO PRO F . n 
F 1 285 LEU 285 304 304 LEU LEU F . n 
F 1 286 THR 286 305 305 THR THR F . n 
F 1 287 GLN 287 306 306 GLN GLN F . n 
F 1 288 LYS 288 307 307 LYS LYS F . n 
F 1 289 ARG 289 308 308 ARG ARG F . n 
F 1 290 ARG 290 309 309 ARG ARG F . n 
F 1 291 VAL 291 310 310 VAL VAL F . n 
F 1 292 ALA 292 311 311 ALA ALA F . n 
F 1 293 LYS 293 312 312 LYS LYS F . n 
F 1 294 ASP 294 313 313 ASP ASP F . n 
F 1 295 SER 295 314 314 SER SER F . n 
F 1 296 LEU 296 315 315 LEU LEU F . n 
F 1 297 LYS 297 316 316 LYS LYS F . n 
F 1 298 PHE 298 317 317 PHE PHE F . n 
F 1 299 PRO 299 318 318 PRO PRO F . n 
F 1 300 LEU 300 319 319 LEU LEU F . n 
F 1 301 ALA 301 320 320 ALA ALA F . n 
F 1 302 CYS 302 321 321 CYS CYS F . n 
F 1 303 PHE 303 322 322 PHE PHE F . n 
F 1 304 LEU 304 323 323 LEU LEU F . n 
F 1 305 ALA 305 324 324 ALA ALA F . n 
F 1 306 GLY 306 325 325 GLY GLY F . n 
F 1 307 ALA 307 326 326 ALA ALA F . n 
F 1 308 GLN 308 327 327 GLN GLN F . n 
F 1 309 GLU 309 328 328 GLU GLU F . n 
F 1 310 ASN 310 329 329 ASN ASN F . n 
F 1 311 CYS 311 330 330 CYS CYS F . n 
F 1 312 TYR 312 331 331 TYR TYR F . n 
F 1 313 PHE 313 332 332 PHE PHE F . n 
F 1 314 ILE 314 333 333 ILE ILE F . n 
F 1 315 TYR 315 334 334 TYR TYR F . n 
F 1 316 ASN 316 335 335 ASN ASN F . n 
F 1 317 TRP 317 336 336 TRP TRP F . n 
F 1 318 GLY 318 337 337 GLY GLY F . n 
F 1 319 TYR 319 338 338 TYR TYR F . n 
F 1 320 ARG 320 339 339 ARG ARG F . n 
F 1 321 MET 321 340 340 MET MET F . n 
F 1 322 GLU 322 341 341 GLU GLU F . n 
F 1 323 ASN 323 342 342 ASN ASN F . n 
F 1 324 GLY 324 343 343 GLY GLY F . n 
F 1 325 CYS 325 344 344 CYS CYS F . n 
F 1 326 LEU 326 345 345 LEU LEU F . n 
F 1 327 GLU 327 346 346 GLU GLU F . n 
F 1 328 TRP 328 347 347 TRP TRP F . n 
F 1 329 TYR 329 348 348 TYR TYR F . n 
F 1 330 PRO 330 349 349 PRO PRO F . n 
F 1 331 GLU 331 350 350 GLU GLU F . n 
F 1 332 PHE 332 351 351 PHE PHE F . n 
F 1 333 ASP 333 352 352 ASP ASP F . n 
F 1 334 LYS 334 353 353 LYS LYS F . n 
F 1 335 PRO 335 354 354 PRO PRO F . n 
F 1 336 LEU 336 355 355 LEU LEU F . n 
F 1 337 GLY 337 356 356 GLY GLY F . n 
F 1 338 LYS 338 357 357 LYS LYS F . n 
F 1 339 PRO 339 358 358 PRO PRO F . n 
F 1 340 VAL 340 359 359 VAL VAL F . n 
F 1 341 GLY 341 360 360 GLY GLY F . n 
F 1 342 GLU 342 361 361 GLU GLU F . n 
F 1 343 MET 343 362 362 MET MET F . n 
F 1 344 VAL 344 363 363 VAL VAL F . n 
F 1 345 ARG 345 364 364 ARG ARG F . n 
F 1 346 ASP 346 365 365 ASP ASP F . n 
F 1 347 GLY 347 366 366 GLY GLY F . n 
F 1 348 TRP 348 367 367 TRP TRP F . n 
F 1 349 LYS 349 368 368 LYS LYS F . n 
F 1 350 LEU 350 369 369 LEU LEU F . n 
F 1 351 SER 351 370 370 SER SER F . n 
F 1 352 ARG 352 371 371 ARG ARG F . n 
F 1 353 GLU 353 372 372 GLU GLU F . n 
F 1 354 TYR 354 373 373 TYR TYR F . n 
F 1 355 LYS 355 374 374 LYS LYS F . n 
F 1 356 HIS 356 375 375 HIS HIS F . n 
F 1 357 ALA 357 376 376 ALA ALA F . n 
F 1 358 SER 358 377 377 SER SER F . n 
F 1 359 VAL 359 378 378 VAL VAL F . n 
F 1 360 ARG 360 379 379 ARG ARG F . n 
F 1 361 VAL 361 380 380 VAL VAL F . n 
F 1 362 ASP 362 381 381 ASP ASP F . n 
F 1 363 LEU 363 382 382 LEU LEU F . n 
F 1 364 GLU 364 383 383 GLU GLU F . n 
F 1 365 SER 365 384 384 SER SER F . n 
F 1 366 LYS 366 385 385 LYS LYS F . n 
F 1 367 GLU 367 386 386 GLU GLU F . n 
F 1 368 ALA 368 387 387 ALA ALA F . n 
F 1 369 GLU 369 388 388 GLU GLU F . n 
F 1 370 ILE 370 389 389 ILE ILE F . n 
F 1 371 ARG 371 390 390 ARG ARG F . n 
F 1 372 TRP 372 391 391 TRP TRP F . n 
F 1 373 ARG 373 392 392 ARG ARG F . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 2 EDO 1  401 1   EDO EDO A . 
H 2 EDO 1  401 2   EDO EDO B . 
I 2 EDO 1  401 3   EDO EDO C . 
J 3 HOH 1  501 39  HOH HOH A . 
J 3 HOH 2  502 26  HOH HOH A . 
J 3 HOH 3  503 14  HOH HOH A . 
J 3 HOH 4  504 128 HOH HOH A . 
J 3 HOH 5  505 27  HOH HOH A . 
J 3 HOH 6  506 95  HOH HOH A . 
J 3 HOH 7  507 124 HOH HOH A . 
J 3 HOH 8  508 22  HOH HOH A . 
J 3 HOH 9  509 54  HOH HOH A . 
J 3 HOH 10 510 48  HOH HOH A . 
J 3 HOH 11 511 62  HOH HOH A . 
J 3 HOH 12 512 9   HOH HOH A . 
J 3 HOH 13 513 31  HOH HOH A . 
J 3 HOH 14 514 164 HOH HOH A . 
J 3 HOH 15 515 160 HOH HOH A . 
J 3 HOH 16 516 156 HOH HOH A . 
J 3 HOH 17 517 86  HOH HOH A . 
J 3 HOH 18 518 105 HOH HOH A . 
J 3 HOH 19 519 100 HOH HOH A . 
J 3 HOH 20 520 81  HOH HOH A . 
J 3 HOH 21 521 69  HOH HOH A . 
J 3 HOH 22 522 36  HOH HOH A . 
J 3 HOH 23 523 142 HOH HOH A . 
J 3 HOH 24 524 18  HOH HOH A . 
J 3 HOH 25 525 144 HOH HOH A . 
J 3 HOH 26 526 140 HOH HOH A . 
J 3 HOH 27 527 59  HOH HOH A . 
J 3 HOH 28 528 13  HOH HOH A . 
J 3 HOH 29 529 131 HOH HOH A . 
J 3 HOH 30 530 126 HOH HOH A . 
J 3 HOH 31 531 58  HOH HOH A . 
J 3 HOH 32 532 163 HOH HOH A . 
J 3 HOH 33 533 158 HOH HOH A . 
K 3 HOH 1  501 89  HOH HOH B . 
K 3 HOH 2  502 117 HOH HOH B . 
K 3 HOH 3  503 130 HOH HOH B . 
K 3 HOH 4  504 35  HOH HOH B . 
K 3 HOH 5  505 2   HOH HOH B . 
K 3 HOH 6  506 53  HOH HOH B . 
K 3 HOH 7  507 120 HOH HOH B . 
K 3 HOH 8  508 132 HOH HOH B . 
K 3 HOH 9  509 16  HOH HOH B . 
K 3 HOH 10 510 77  HOH HOH B . 
K 3 HOH 11 511 30  HOH HOH B . 
K 3 HOH 12 512 42  HOH HOH B . 
K 3 HOH 13 513 75  HOH HOH B . 
K 3 HOH 14 514 136 HOH HOH B . 
K 3 HOH 15 515 123 HOH HOH B . 
K 3 HOH 16 516 97  HOH HOH B . 
K 3 HOH 17 517 5   HOH HOH B . 
K 3 HOH 18 518 116 HOH HOH B . 
K 3 HOH 19 519 7   HOH HOH B . 
K 3 HOH 20 520 70  HOH HOH B . 
K 3 HOH 21 521 91  HOH HOH B . 
K 3 HOH 22 522 129 HOH HOH B . 
K 3 HOH 23 523 6   HOH HOH B . 
K 3 HOH 24 524 11  HOH HOH B . 
K 3 HOH 25 525 68  HOH HOH B . 
K 3 HOH 26 526 49  HOH HOH B . 
K 3 HOH 27 527 33  HOH HOH B . 
K 3 HOH 28 528 83  HOH HOH B . 
K 3 HOH 29 529 133 HOH HOH B . 
K 3 HOH 30 530 93  HOH HOH B . 
K 3 HOH 31 531 28  HOH HOH B . 
K 3 HOH 32 532 135 HOH HOH B . 
K 3 HOH 33 533 19  HOH HOH B . 
K 3 HOH 34 534 25  HOH HOH B . 
K 3 HOH 35 535 78  HOH HOH B . 
K 3 HOH 36 536 115 HOH HOH B . 
K 3 HOH 37 537 80  HOH HOH B . 
K 3 HOH 38 538 112 HOH HOH B . 
K 3 HOH 39 539 110 HOH HOH B . 
K 3 HOH 40 540 146 HOH HOH B . 
K 3 HOH 41 541 162 HOH HOH B . 
K 3 HOH 42 542 43  HOH HOH B . 
K 3 HOH 43 543 67  HOH HOH B . 
K 3 HOH 44 544 73  HOH HOH B . 
K 3 HOH 45 545 138 HOH HOH B . 
K 3 HOH 46 546 139 HOH HOH B . 
K 3 HOH 47 547 64  HOH HOH B . 
L 3 HOH 1  501 102 HOH HOH C . 
L 3 HOH 2  502 150 HOH HOH C . 
L 3 HOH 3  503 119 HOH HOH C . 
L 3 HOH 4  504 47  HOH HOH C . 
L 3 HOH 5  505 51  HOH HOH C . 
L 3 HOH 6  506 56  HOH HOH C . 
L 3 HOH 7  507 21  HOH HOH C . 
L 3 HOH 8  508 87  HOH HOH C . 
L 3 HOH 9  509 122 HOH HOH C . 
L 3 HOH 10 510 125 HOH HOH C . 
L 3 HOH 11 511 37  HOH HOH C . 
L 3 HOH 12 512 4   HOH HOH C . 
L 3 HOH 13 513 45  HOH HOH C . 
L 3 HOH 14 514 60  HOH HOH C . 
L 3 HOH 15 515 38  HOH HOH C . 
L 3 HOH 16 516 61  HOH HOH C . 
L 3 HOH 17 517 111 HOH HOH C . 
L 3 HOH 18 518 71  HOH HOH C . 
L 3 HOH 19 519 32  HOH HOH C . 
L 3 HOH 20 520 106 HOH HOH C . 
L 3 HOH 21 521 63  HOH HOH C . 
L 3 HOH 22 522 76  HOH HOH C . 
L 3 HOH 23 523 79  HOH HOH C . 
L 3 HOH 24 524 55  HOH HOH C . 
L 3 HOH 25 525 161 HOH HOH C . 
L 3 HOH 26 526 74  HOH HOH C . 
L 3 HOH 27 527 84  HOH HOH C . 
L 3 HOH 28 528 44  HOH HOH C . 
L 3 HOH 29 529 85  HOH HOH C . 
L 3 HOH 30 530 82  HOH HOH C . 
L 3 HOH 31 531 159 HOH HOH C . 
L 3 HOH 32 532 46  HOH HOH C . 
M 3 HOH 1  401 101 HOH HOH D . 
M 3 HOH 2  402 1   HOH HOH D . 
M 3 HOH 3  403 109 HOH HOH D . 
M 3 HOH 4  404 12  HOH HOH D . 
M 3 HOH 5  405 118 HOH HOH D . 
M 3 HOH 6  406 52  HOH HOH D . 
M 3 HOH 7  407 17  HOH HOH D . 
M 3 HOH 8  408 29  HOH HOH D . 
M 3 HOH 9  409 134 HOH HOH D . 
M 3 HOH 10 410 66  HOH HOH D . 
M 3 HOH 11 411 141 HOH HOH D . 
M 3 HOH 12 412 127 HOH HOH D . 
M 3 HOH 13 413 90  HOH HOH D . 
M 3 HOH 14 414 10  HOH HOH D . 
M 3 HOH 15 415 107 HOH HOH D . 
M 3 HOH 16 416 92  HOH HOH D . 
M 3 HOH 17 417 88  HOH HOH D . 
M 3 HOH 18 418 40  HOH HOH D . 
M 3 HOH 19 419 104 HOH HOH D . 
M 3 HOH 20 420 65  HOH HOH D . 
M 3 HOH 21 421 24  HOH HOH D . 
M 3 HOH 22 422 148 HOH HOH D . 
M 3 HOH 23 423 108 HOH HOH D . 
M 3 HOH 24 424 154 HOH HOH D . 
M 3 HOH 25 425 145 HOH HOH D . 
M 3 HOH 26 426 114 HOH HOH D . 
M 3 HOH 27 427 149 HOH HOH D . 
N 3 HOH 1  401 72  HOH HOH E . 
N 3 HOH 2  402 34  HOH HOH E . 
N 3 HOH 3  403 50  HOH HOH E . 
N 3 HOH 4  404 41  HOH HOH E . 
N 3 HOH 5  405 165 HOH HOH E . 
N 3 HOH 6  406 8   HOH HOH E . 
N 3 HOH 7  407 20  HOH HOH E . 
N 3 HOH 8  408 152 HOH HOH E . 
N 3 HOH 9  409 103 HOH HOH E . 
N 3 HOH 10 410 157 HOH HOH E . 
N 3 HOH 11 411 23  HOH HOH E . 
N 3 HOH 12 412 121 HOH HOH E . 
N 3 HOH 13 413 147 HOH HOH E . 
N 3 HOH 14 414 57  HOH HOH E . 
N 3 HOH 15 415 151 HOH HOH E . 
N 3 HOH 16 416 166 HOH HOH E . 
N 3 HOH 17 417 98  HOH HOH E . 
N 3 HOH 18 418 94  HOH HOH E . 
N 3 HOH 19 419 137 HOH HOH E . 
N 3 HOH 20 420 143 HOH HOH E . 
N 3 HOH 21 421 96  HOH HOH E . 
N 3 HOH 22 422 113 HOH HOH E . 
O 3 HOH 1  401 155 HOH HOH F . 
O 3 HOH 2  402 153 HOH HOH F . 
O 3 HOH 3  403 15  HOH HOH F . 
O 3 HOH 4  404 99  HOH HOH F . 
O 3 HOH 5  405 3   HOH HOH F . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A GLU 37  ? CG  ? A GLU 18  CG  
2   1 Y 1 A GLU 37  ? CD  ? A GLU 18  CD  
3   1 Y 1 A GLU 37  ? OE1 ? A GLU 18  OE1 
4   1 Y 1 A GLU 37  ? OE2 ? A GLU 18  OE2 
5   1 Y 1 A GLU 42  ? CG  ? A GLU 23  CG  
6   1 Y 1 A GLU 42  ? CD  ? A GLU 23  CD  
7   1 Y 1 A GLU 42  ? OE1 ? A GLU 23  OE1 
8   1 Y 1 A GLU 42  ? OE2 ? A GLU 23  OE2 
9   1 Y 1 A GLU 128 ? CG  ? A GLU 109 CG  
10  1 Y 1 A GLU 128 ? CD  ? A GLU 109 CD  
11  1 Y 1 A GLU 128 ? OE1 ? A GLU 109 OE1 
12  1 Y 1 A GLU 128 ? OE2 ? A GLU 109 OE2 
13  1 Y 1 A GLU 143 ? CG  ? A GLU 124 CG  
14  1 Y 1 A GLU 143 ? CD  ? A GLU 124 CD  
15  1 Y 1 A GLU 143 ? OE1 ? A GLU 124 OE1 
16  1 Y 1 A GLU 143 ? OE2 ? A GLU 124 OE2 
17  1 Y 1 A LYS 148 ? CG  ? A LYS 129 CG  
18  1 Y 1 A LYS 148 ? CD  ? A LYS 129 CD  
19  1 Y 1 A LYS 148 ? CE  ? A LYS 129 CE  
20  1 Y 1 A LYS 148 ? NZ  ? A LYS 129 NZ  
21  1 Y 1 A LYS 196 ? CG  ? A LYS 177 CG  
22  1 Y 1 A LYS 196 ? CD  ? A LYS 177 CD  
23  1 Y 1 A LYS 196 ? CE  ? A LYS 177 CE  
24  1 Y 1 A LYS 196 ? NZ  ? A LYS 177 NZ  
25  1 Y 1 A GLU 201 ? CG  ? A GLU 182 CG  
26  1 Y 1 A GLU 201 ? CD  ? A GLU 182 CD  
27  1 Y 1 A GLU 201 ? OE1 ? A GLU 182 OE1 
28  1 Y 1 A GLU 201 ? OE2 ? A GLU 182 OE2 
29  1 Y 1 A GLN 211 ? CG  ? A GLN 192 CG  
30  1 Y 1 A GLN 211 ? CD  ? A GLN 192 CD  
31  1 Y 1 A GLN 211 ? OE1 ? A GLN 192 OE1 
32  1 Y 1 A GLN 211 ? NE2 ? A GLN 192 NE2 
33  1 Y 1 A ASP 243 ? CG  ? A ASP 224 CG  
34  1 Y 1 A ASP 243 ? OD1 ? A ASP 224 OD1 
35  1 Y 1 A ASP 243 ? OD2 ? A ASP 224 OD2 
36  1 Y 1 A GLU 246 ? CG  ? A GLU 227 CG  
37  1 Y 1 A GLU 246 ? CD  ? A GLU 227 CD  
38  1 Y 1 A GLU 246 ? OE1 ? A GLU 227 OE1 
39  1 Y 1 A GLU 246 ? OE2 ? A GLU 227 OE2 
40  1 Y 1 A GLN 260 ? CG  ? A GLN 241 CG  
41  1 Y 1 A GLN 260 ? CD  ? A GLN 241 CD  
42  1 Y 1 A GLN 260 ? OE1 ? A GLN 241 OE1 
43  1 Y 1 A GLN 260 ? NE2 ? A GLN 241 NE2 
44  1 Y 1 A ASP 297 ? CG  ? A ASP 278 CG  
45  1 Y 1 A ASP 297 ? OD1 ? A ASP 278 OD1 
46  1 Y 1 A ASP 297 ? OD2 ? A ASP 278 OD2 
47  1 Y 1 A GLN 298 ? CG  ? A GLN 279 CG  
48  1 Y 1 A GLN 298 ? CD  ? A GLN 279 CD  
49  1 Y 1 A GLN 298 ? OE1 ? A GLN 279 OE1 
50  1 Y 1 A GLN 298 ? NE2 ? A GLN 279 NE2 
51  1 Y 1 A GLU 341 ? CG  ? A GLU 322 CG  
52  1 Y 1 A GLU 341 ? CD  ? A GLU 322 CD  
53  1 Y 1 A GLU 341 ? OE1 ? A GLU 322 OE1 
54  1 Y 1 A GLU 341 ? OE2 ? A GLU 322 OE2 
55  1 Y 1 A LYS 374 ? CG  ? A LYS 355 CG  
56  1 Y 1 A LYS 374 ? CD  ? A LYS 355 CD  
57  1 Y 1 A LYS 374 ? CE  ? A LYS 355 CE  
58  1 Y 1 A LYS 374 ? NZ  ? A LYS 355 NZ  
59  1 Y 1 A GLU 388 ? CG  ? A GLU 369 CG  
60  1 Y 1 A GLU 388 ? CD  ? A GLU 369 CD  
61  1 Y 1 A GLU 388 ? OE1 ? A GLU 369 OE1 
62  1 Y 1 A GLU 388 ? OE2 ? A GLU 369 OE2 
63  1 Y 1 A ARG 390 ? CG  ? A ARG 371 CG  
64  1 Y 1 A ARG 390 ? CD  ? A ARG 371 CD  
65  1 Y 1 A ARG 390 ? NE  ? A ARG 371 NE  
66  1 Y 1 A ARG 390 ? CZ  ? A ARG 371 CZ  
67  1 Y 1 A ARG 390 ? NH1 ? A ARG 371 NH1 
68  1 Y 1 A ARG 390 ? NH2 ? A ARG 371 NH2 
69  1 Y 1 B LYS 63  ? CG  ? B LYS 44  CG  
70  1 Y 1 B LYS 63  ? CD  ? B LYS 44  CD  
71  1 Y 1 B LYS 63  ? CE  ? B LYS 44  CE  
72  1 Y 1 B LYS 63  ? NZ  ? B LYS 44  NZ  
73  1 Y 1 B GLU 64  ? CG  ? B GLU 45  CG  
74  1 Y 1 B GLU 64  ? CD  ? B GLU 45  CD  
75  1 Y 1 B GLU 64  ? OE1 ? B GLU 45  OE1 
76  1 Y 1 B GLU 64  ? OE2 ? B GLU 45  OE2 
77  1 Y 1 B GLU 67  ? CG  ? B GLU 48  CG  
78  1 Y 1 B GLU 67  ? CD  ? B GLU 48  CD  
79  1 Y 1 B GLU 67  ? OE1 ? B GLU 48  OE1 
80  1 Y 1 B GLU 67  ? OE2 ? B GLU 48  OE2 
81  1 Y 1 B GLU 128 ? CG  ? B GLU 109 CG  
82  1 Y 1 B GLU 128 ? CD  ? B GLU 109 CD  
83  1 Y 1 B GLU 128 ? OE1 ? B GLU 109 OE1 
84  1 Y 1 B GLU 128 ? OE2 ? B GLU 109 OE2 
85  1 Y 1 B LYS 131 ? CG  ? B LYS 112 CG  
86  1 Y 1 B LYS 131 ? CD  ? B LYS 112 CD  
87  1 Y 1 B LYS 131 ? CE  ? B LYS 112 CE  
88  1 Y 1 B LYS 131 ? NZ  ? B LYS 112 NZ  
89  1 Y 1 B GLU 143 ? CG  ? B GLU 124 CG  
90  1 Y 1 B GLU 143 ? CD  ? B GLU 124 CD  
91  1 Y 1 B GLU 143 ? OE1 ? B GLU 124 OE1 
92  1 Y 1 B GLU 143 ? OE2 ? B GLU 124 OE2 
93  1 Y 1 B LYS 148 ? CG  ? B LYS 129 CG  
94  1 Y 1 B LYS 148 ? CD  ? B LYS 129 CD  
95  1 Y 1 B LYS 148 ? CE  ? B LYS 129 CE  
96  1 Y 1 B LYS 148 ? NZ  ? B LYS 129 NZ  
97  1 Y 1 B GLN 150 ? CG  ? B GLN 131 CG  
98  1 Y 1 B GLN 150 ? CD  ? B GLN 131 CD  
99  1 Y 1 B GLN 150 ? OE1 ? B GLN 131 OE1 
100 1 Y 1 B GLN 150 ? NE2 ? B GLN 131 NE2 
101 1 Y 1 B LYS 196 ? CG  ? B LYS 177 CG  
102 1 Y 1 B LYS 196 ? CD  ? B LYS 177 CD  
103 1 Y 1 B LYS 196 ? CE  ? B LYS 177 CE  
104 1 Y 1 B LYS 196 ? NZ  ? B LYS 177 NZ  
105 1 Y 1 B ASP 237 ? CG  ? B ASP 218 CG  
106 1 Y 1 B ASP 237 ? OD1 ? B ASP 218 OD1 
107 1 Y 1 B ASP 237 ? OD2 ? B ASP 218 OD2 
108 1 Y 1 B ASP 297 ? CG  ? B ASP 278 CG  
109 1 Y 1 B ASP 297 ? OD1 ? B ASP 278 OD1 
110 1 Y 1 B ASP 297 ? OD2 ? B ASP 278 OD2 
111 1 Y 1 B ARG 301 ? CG  ? B ARG 282 CG  
112 1 Y 1 B ARG 301 ? CD  ? B ARG 282 CD  
113 1 Y 1 B ARG 301 ? NE  ? B ARG 282 NE  
114 1 Y 1 B ARG 301 ? CZ  ? B ARG 282 CZ  
115 1 Y 1 B ARG 301 ? NH1 ? B ARG 282 NH1 
116 1 Y 1 B ARG 301 ? NH2 ? B ARG 282 NH2 
117 1 Y 1 B LYS 312 ? CG  ? B LYS 293 CG  
118 1 Y 1 B LYS 312 ? CD  ? B LYS 293 CD  
119 1 Y 1 B LYS 312 ? CE  ? B LYS 293 CE  
120 1 Y 1 B LYS 312 ? NZ  ? B LYS 293 NZ  
121 1 Y 1 B LYS 357 ? CG  ? B LYS 338 CG  
122 1 Y 1 B LYS 357 ? CD  ? B LYS 338 CD  
123 1 Y 1 B LYS 357 ? CE  ? B LYS 338 CE  
124 1 Y 1 B LYS 357 ? NZ  ? B LYS 338 NZ  
125 1 Y 1 B LYS 368 ? CG  ? B LYS 349 CG  
126 1 Y 1 B LYS 368 ? CD  ? B LYS 349 CD  
127 1 Y 1 B LYS 368 ? CE  ? B LYS 349 CE  
128 1 Y 1 B LYS 368 ? NZ  ? B LYS 349 NZ  
129 1 Y 1 B LYS 374 ? CG  ? B LYS 355 CG  
130 1 Y 1 B LYS 374 ? CD  ? B LYS 355 CD  
131 1 Y 1 B LYS 374 ? CE  ? B LYS 355 CE  
132 1 Y 1 B LYS 374 ? NZ  ? B LYS 355 NZ  
133 1 Y 1 B ARG 379 ? CG  ? B ARG 360 CG  
134 1 Y 1 B ARG 379 ? CD  ? B ARG 360 CD  
135 1 Y 1 B ARG 379 ? NE  ? B ARG 360 NE  
136 1 Y 1 B ARG 379 ? CZ  ? B ARG 360 CZ  
137 1 Y 1 B ARG 379 ? NH1 ? B ARG 360 NH1 
138 1 Y 1 B ARG 379 ? NH2 ? B ARG 360 NH2 
139 1 Y 1 B GLU 383 ? CG  ? B GLU 364 CG  
140 1 Y 1 B GLU 383 ? CD  ? B GLU 364 CD  
141 1 Y 1 B GLU 383 ? OE1 ? B GLU 364 OE1 
142 1 Y 1 B GLU 383 ? OE2 ? B GLU 364 OE2 
143 1 Y 1 B GLU 386 ? CG  ? B GLU 367 CG  
144 1 Y 1 B GLU 386 ? CD  ? B GLU 367 CD  
145 1 Y 1 B GLU 386 ? OE1 ? B GLU 367 OE1 
146 1 Y 1 B GLU 386 ? OE2 ? B GLU 367 OE2 
147 1 Y 1 B GLU 388 ? CG  ? B GLU 369 CG  
148 1 Y 1 B GLU 388 ? CD  ? B GLU 369 CD  
149 1 Y 1 B GLU 388 ? OE1 ? B GLU 369 OE1 
150 1 Y 1 B GLU 388 ? OE2 ? B GLU 369 OE2 
151 1 Y 1 B ARG 390 ? CG  ? B ARG 371 CG  
152 1 Y 1 B ARG 390 ? CD  ? B ARG 371 CD  
153 1 Y 1 B ARG 390 ? NE  ? B ARG 371 NE  
154 1 Y 1 B ARG 390 ? CZ  ? B ARG 371 CZ  
155 1 Y 1 B ARG 390 ? NH1 ? B ARG 371 NH1 
156 1 Y 1 B ARG 390 ? NH2 ? B ARG 371 NH2 
157 1 Y 1 B ARG 392 ? CG  ? B ARG 373 CG  
158 1 Y 1 B ARG 392 ? CD  ? B ARG 373 CD  
159 1 Y 1 B ARG 392 ? NE  ? B ARG 373 NE  
160 1 Y 1 B ARG 392 ? CZ  ? B ARG 373 CZ  
161 1 Y 1 B ARG 392 ? NH1 ? B ARG 373 NH1 
162 1 Y 1 B ARG 392 ? NH2 ? B ARG 373 NH2 
163 1 Y 1 C GLU 37  ? CG  ? C GLU 18  CG  
164 1 Y 1 C GLU 37  ? CD  ? C GLU 18  CD  
165 1 Y 1 C GLU 37  ? OE1 ? C GLU 18  OE1 
166 1 Y 1 C GLU 37  ? OE2 ? C GLU 18  OE2 
167 1 Y 1 C LYS 63  ? CG  ? C LYS 44  CG  
168 1 Y 1 C LYS 63  ? CD  ? C LYS 44  CD  
169 1 Y 1 C LYS 63  ? CE  ? C LYS 44  CE  
170 1 Y 1 C LYS 63  ? NZ  ? C LYS 44  NZ  
171 1 Y 1 C GLU 64  ? CG  ? C GLU 45  CG  
172 1 Y 1 C GLU 64  ? CD  ? C GLU 45  CD  
173 1 Y 1 C GLU 64  ? OE1 ? C GLU 45  OE1 
174 1 Y 1 C GLU 64  ? OE2 ? C GLU 45  OE2 
175 1 Y 1 C GLU 67  ? CG  ? C GLU 48  CG  
176 1 Y 1 C GLU 67  ? CD  ? C GLU 48  CD  
177 1 Y 1 C GLU 67  ? OE1 ? C GLU 48  OE1 
178 1 Y 1 C GLU 67  ? OE2 ? C GLU 48  OE2 
179 1 Y 1 C ARG 138 ? CG  ? C ARG 119 CG  
180 1 Y 1 C ARG 138 ? CD  ? C ARG 119 CD  
181 1 Y 1 C ARG 138 ? NE  ? C ARG 119 NE  
182 1 Y 1 C ARG 138 ? CZ  ? C ARG 119 CZ  
183 1 Y 1 C ARG 138 ? NH1 ? C ARG 119 NH1 
184 1 Y 1 C ARG 138 ? NH2 ? C ARG 119 NH2 
185 1 Y 1 C GLU 143 ? CG  ? C GLU 124 CG  
186 1 Y 1 C GLU 143 ? CD  ? C GLU 124 CD  
187 1 Y 1 C GLU 143 ? OE1 ? C GLU 124 OE1 
188 1 Y 1 C GLU 143 ? OE2 ? C GLU 124 OE2 
189 1 Y 1 C LYS 148 ? CG  ? C LYS 129 CG  
190 1 Y 1 C LYS 148 ? CD  ? C LYS 129 CD  
191 1 Y 1 C LYS 148 ? CE  ? C LYS 129 CE  
192 1 Y 1 C LYS 148 ? NZ  ? C LYS 129 NZ  
193 1 Y 1 C GLN 150 ? CG  ? C GLN 131 CG  
194 1 Y 1 C GLN 150 ? CD  ? C GLN 131 CD  
195 1 Y 1 C GLN 150 ? OE1 ? C GLN 131 OE1 
196 1 Y 1 C GLN 150 ? NE2 ? C GLN 131 NE2 
197 1 Y 1 C LYS 196 ? CG  ? C LYS 177 CG  
198 1 Y 1 C LYS 196 ? CD  ? C LYS 177 CD  
199 1 Y 1 C LYS 196 ? CE  ? C LYS 177 CE  
200 1 Y 1 C LYS 196 ? NZ  ? C LYS 177 NZ  
201 1 Y 1 C GLU 201 ? CG  ? C GLU 182 CG  
202 1 Y 1 C GLU 201 ? CD  ? C GLU 182 CD  
203 1 Y 1 C GLU 201 ? OE1 ? C GLU 182 OE1 
204 1 Y 1 C GLU 201 ? OE2 ? C GLU 182 OE2 
205 1 Y 1 C GLU 204 ? CG  ? C GLU 185 CG  
206 1 Y 1 C GLU 204 ? CD  ? C GLU 185 CD  
207 1 Y 1 C GLU 204 ? OE1 ? C GLU 185 OE1 
208 1 Y 1 C GLU 204 ? OE2 ? C GLU 185 OE2 
209 1 Y 1 C ASP 237 ? CG  ? C ASP 218 CG  
210 1 Y 1 C ASP 237 ? OD1 ? C ASP 218 OD1 
211 1 Y 1 C ASP 237 ? OD2 ? C ASP 218 OD2 
212 1 Y 1 C GLU 246 ? CG  ? C GLU 227 CG  
213 1 Y 1 C GLU 246 ? CD  ? C GLU 227 CD  
214 1 Y 1 C GLU 246 ? OE1 ? C GLU 227 OE1 
215 1 Y 1 C GLU 246 ? OE2 ? C GLU 227 OE2 
216 1 Y 1 C ARG 269 ? CG  ? C ARG 250 CG  
217 1 Y 1 C ARG 269 ? CD  ? C ARG 250 CD  
218 1 Y 1 C ARG 269 ? NE  ? C ARG 250 NE  
219 1 Y 1 C ARG 269 ? CZ  ? C ARG 250 CZ  
220 1 Y 1 C ARG 269 ? NH1 ? C ARG 250 NH1 
221 1 Y 1 C ARG 269 ? NH2 ? C ARG 250 NH2 
222 1 Y 1 C ASP 297 ? CG  ? C ASP 278 CG  
223 1 Y 1 C ASP 297 ? OD1 ? C ASP 278 OD1 
224 1 Y 1 C ASP 297 ? OD2 ? C ASP 278 OD2 
225 1 Y 1 C GLN 298 ? CG  ? C GLN 279 CG  
226 1 Y 1 C GLN 298 ? CD  ? C GLN 279 CD  
227 1 Y 1 C GLN 298 ? OE1 ? C GLN 279 OE1 
228 1 Y 1 C GLN 298 ? NE2 ? C GLN 279 NE2 
229 1 Y 1 C ARG 301 ? CG  ? C ARG 282 CG  
230 1 Y 1 C ARG 301 ? CD  ? C ARG 282 CD  
231 1 Y 1 C ARG 301 ? NE  ? C ARG 282 NE  
232 1 Y 1 C ARG 301 ? CZ  ? C ARG 282 CZ  
233 1 Y 1 C ARG 301 ? NH1 ? C ARG 282 NH1 
234 1 Y 1 C ARG 301 ? NH2 ? C ARG 282 NH2 
235 1 Y 1 C ARG 309 ? CG  ? C ARG 290 CG  
236 1 Y 1 C ARG 309 ? CD  ? C ARG 290 CD  
237 1 Y 1 C ARG 309 ? NE  ? C ARG 290 NE  
238 1 Y 1 C ARG 309 ? CZ  ? C ARG 290 CZ  
239 1 Y 1 C ARG 309 ? NH1 ? C ARG 290 NH1 
240 1 Y 1 C ARG 309 ? NH2 ? C ARG 290 NH2 
241 1 Y 1 C LYS 312 ? CG  ? C LYS 293 CG  
242 1 Y 1 C LYS 312 ? CD  ? C LYS 293 CD  
243 1 Y 1 C LYS 312 ? CE  ? C LYS 293 CE  
244 1 Y 1 C LYS 312 ? NZ  ? C LYS 293 NZ  
245 1 Y 1 C GLU 328 ? CG  ? C GLU 309 CG  
246 1 Y 1 C GLU 328 ? CD  ? C GLU 309 CD  
247 1 Y 1 C GLU 328 ? OE1 ? C GLU 309 OE1 
248 1 Y 1 C GLU 328 ? OE2 ? C GLU 309 OE2 
249 1 Y 1 C ARG 339 ? CG  ? C ARG 320 CG  
250 1 Y 1 C ARG 339 ? CD  ? C ARG 320 CD  
251 1 Y 1 C ARG 339 ? NE  ? C ARG 320 NE  
252 1 Y 1 C ARG 339 ? CZ  ? C ARG 320 CZ  
253 1 Y 1 C ARG 339 ? NH1 ? C ARG 320 NH1 
254 1 Y 1 C ARG 339 ? NH2 ? C ARG 320 NH2 
255 1 Y 1 C LYS 357 ? CG  ? C LYS 338 CG  
256 1 Y 1 C LYS 357 ? CD  ? C LYS 338 CD  
257 1 Y 1 C LYS 357 ? CE  ? C LYS 338 CE  
258 1 Y 1 C LYS 357 ? NZ  ? C LYS 338 NZ  
259 1 Y 1 C ASP 365 ? CG  ? C ASP 346 CG  
260 1 Y 1 C ASP 365 ? OD1 ? C ASP 346 OD1 
261 1 Y 1 C ASP 365 ? OD2 ? C ASP 346 OD2 
262 1 Y 1 C LYS 374 ? CG  ? C LYS 355 CG  
263 1 Y 1 C LYS 374 ? CD  ? C LYS 355 CD  
264 1 Y 1 C LYS 374 ? CE  ? C LYS 355 CE  
265 1 Y 1 C LYS 374 ? NZ  ? C LYS 355 NZ  
266 1 Y 1 C GLU 388 ? CG  ? C GLU 369 CG  
267 1 Y 1 C GLU 388 ? CD  ? C GLU 369 CD  
268 1 Y 1 C GLU 388 ? OE1 ? C GLU 369 OE1 
269 1 Y 1 C GLU 388 ? OE2 ? C GLU 369 OE2 
270 1 Y 1 D GLU 37  ? CG  ? D GLU 18  CG  
271 1 Y 1 D GLU 37  ? CD  ? D GLU 18  CD  
272 1 Y 1 D GLU 37  ? OE1 ? D GLU 18  OE1 
273 1 Y 1 D GLU 37  ? OE2 ? D GLU 18  OE2 
274 1 Y 1 D HIS 39  ? CG  ? D HIS 20  CG  
275 1 Y 1 D HIS 39  ? ND1 ? D HIS 20  ND1 
276 1 Y 1 D HIS 39  ? CD2 ? D HIS 20  CD2 
277 1 Y 1 D HIS 39  ? CE1 ? D HIS 20  CE1 
278 1 Y 1 D HIS 39  ? NE2 ? D HIS 20  NE2 
279 1 Y 1 D GLU 42  ? CG  ? D GLU 23  CG  
280 1 Y 1 D GLU 42  ? CD  ? D GLU 23  CD  
281 1 Y 1 D GLU 42  ? OE1 ? D GLU 23  OE1 
282 1 Y 1 D GLU 42  ? OE2 ? D GLU 23  OE2 
283 1 Y 1 D SER 57  ? OG  ? D SER 38  OG  
284 1 Y 1 D GLN 58  ? CG  ? D GLN 39  CG  
285 1 Y 1 D GLN 58  ? CD  ? D GLN 39  CD  
286 1 Y 1 D GLN 58  ? OE1 ? D GLN 39  OE1 
287 1 Y 1 D GLN 58  ? NE2 ? D GLN 39  NE2 
288 1 Y 1 D LYS 63  ? CG  ? D LYS 44  CG  
289 1 Y 1 D LYS 63  ? CD  ? D LYS 44  CD  
290 1 Y 1 D LYS 63  ? CE  ? D LYS 44  CE  
291 1 Y 1 D LYS 63  ? NZ  ? D LYS 44  NZ  
292 1 Y 1 D GLU 64  ? CG  ? D GLU 45  CG  
293 1 Y 1 D GLU 64  ? CD  ? D GLU 45  CD  
294 1 Y 1 D GLU 64  ? OE1 ? D GLU 45  OE1 
295 1 Y 1 D GLU 64  ? OE2 ? D GLU 45  OE2 
296 1 Y 1 D GLU 67  ? CG  ? D GLU 48  CG  
297 1 Y 1 D GLU 67  ? CD  ? D GLU 48  CD  
298 1 Y 1 D GLU 67  ? OE1 ? D GLU 48  OE1 
299 1 Y 1 D GLU 67  ? OE2 ? D GLU 48  OE2 
300 1 Y 1 D ARG 85  ? CG  ? D ARG 66  CG  
301 1 Y 1 D ARG 85  ? CD  ? D ARG 66  CD  
302 1 Y 1 D ARG 85  ? NE  ? D ARG 66  NE  
303 1 Y 1 D ARG 85  ? CZ  ? D ARG 66  CZ  
304 1 Y 1 D ARG 85  ? NH1 ? D ARG 66  NH1 
305 1 Y 1 D ARG 85  ? NH2 ? D ARG 66  NH2 
306 1 Y 1 D ASN 103 ? CG  ? D ASN 84  CG  
307 1 Y 1 D ASN 103 ? OD1 ? D ASN 84  OD1 
308 1 Y 1 D ASN 103 ? ND2 ? D ASN 84  ND2 
309 1 Y 1 D LEU 104 ? CG  ? D LEU 85  CG  
310 1 Y 1 D LEU 104 ? CD1 ? D LEU 85  CD1 
311 1 Y 1 D LEU 104 ? CD2 ? D LEU 85  CD2 
312 1 Y 1 D LYS 127 ? CG  ? D LYS 108 CG  
313 1 Y 1 D LYS 127 ? CD  ? D LYS 108 CD  
314 1 Y 1 D LYS 127 ? CE  ? D LYS 108 CE  
315 1 Y 1 D LYS 127 ? NZ  ? D LYS 108 NZ  
316 1 Y 1 D LYS 131 ? CG  ? D LYS 112 CG  
317 1 Y 1 D LYS 131 ? CD  ? D LYS 112 CD  
318 1 Y 1 D LYS 131 ? CE  ? D LYS 112 CE  
319 1 Y 1 D LYS 131 ? NZ  ? D LYS 112 NZ  
320 1 Y 1 D ARG 146 ? CG  ? D ARG 127 CG  
321 1 Y 1 D ARG 146 ? CD  ? D ARG 127 CD  
322 1 Y 1 D ARG 146 ? NE  ? D ARG 127 NE  
323 1 Y 1 D ARG 146 ? CZ  ? D ARG 127 CZ  
324 1 Y 1 D ARG 146 ? NH1 ? D ARG 127 NH1 
325 1 Y 1 D ARG 146 ? NH2 ? D ARG 127 NH2 
326 1 Y 1 D LYS 148 ? CG  ? D LYS 129 CG  
327 1 Y 1 D LYS 148 ? CD  ? D LYS 129 CD  
328 1 Y 1 D LYS 148 ? CE  ? D LYS 129 CE  
329 1 Y 1 D LYS 148 ? NZ  ? D LYS 129 NZ  
330 1 Y 1 D GLN 150 ? CG  ? D GLN 131 CG  
331 1 Y 1 D GLN 150 ? CD  ? D GLN 131 CD  
332 1 Y 1 D GLN 150 ? OE1 ? D GLN 131 OE1 
333 1 Y 1 D GLN 150 ? NE2 ? D GLN 131 NE2 
334 1 Y 1 D GLU 160 ? CG  ? D GLU 141 CG  
335 1 Y 1 D GLU 160 ? CD  ? D GLU 141 CD  
336 1 Y 1 D GLU 160 ? OE1 ? D GLU 141 OE1 
337 1 Y 1 D GLU 160 ? OE2 ? D GLU 141 OE2 
338 1 Y 1 D LYS 171 ? CG  ? D LYS 152 CG  
339 1 Y 1 D LYS 171 ? CD  ? D LYS 152 CD  
340 1 Y 1 D LYS 171 ? CE  ? D LYS 152 CE  
341 1 Y 1 D LYS 171 ? NZ  ? D LYS 152 NZ  
342 1 Y 1 D ASP 175 ? CG  ? D ASP 156 CG  
343 1 Y 1 D ASP 175 ? OD1 ? D ASP 156 OD1 
344 1 Y 1 D ASP 175 ? OD2 ? D ASP 156 OD2 
345 1 Y 1 D LYS 196 ? CG  ? D LYS 177 CG  
346 1 Y 1 D LYS 196 ? CD  ? D LYS 177 CD  
347 1 Y 1 D LYS 196 ? CE  ? D LYS 177 CE  
348 1 Y 1 D LYS 196 ? NZ  ? D LYS 177 NZ  
349 1 Y 1 D GLU 201 ? CG  ? D GLU 182 CG  
350 1 Y 1 D GLU 201 ? CD  ? D GLU 182 CD  
351 1 Y 1 D GLU 201 ? OE1 ? D GLU 182 OE1 
352 1 Y 1 D GLU 201 ? OE2 ? D GLU 182 OE2 
353 1 Y 1 D GLN 215 ? CG  ? D GLN 196 CG  
354 1 Y 1 D GLN 215 ? CD  ? D GLN 196 CD  
355 1 Y 1 D GLN 215 ? OE1 ? D GLN 196 OE1 
356 1 Y 1 D GLN 215 ? NE2 ? D GLN 196 NE2 
357 1 Y 1 D GLU 216 ? CG  ? D GLU 197 CG  
358 1 Y 1 D GLU 216 ? CD  ? D GLU 197 CD  
359 1 Y 1 D GLU 216 ? OE1 ? D GLU 197 OE1 
360 1 Y 1 D GLU 216 ? OE2 ? D GLU 197 OE2 
361 1 Y 1 D GLN 219 ? CG  ? D GLN 200 CG  
362 1 Y 1 D GLN 219 ? CD  ? D GLN 200 CD  
363 1 Y 1 D GLN 219 ? OE1 ? D GLN 200 OE1 
364 1 Y 1 D GLN 219 ? NE2 ? D GLN 200 NE2 
365 1 Y 1 D ASP 223 ? CG  ? D ASP 204 CG  
366 1 Y 1 D ASP 223 ? OD1 ? D ASP 204 OD1 
367 1 Y 1 D ASP 223 ? OD2 ? D ASP 204 OD2 
368 1 Y 1 D ASP 224 ? CG  ? D ASP 205 CG  
369 1 Y 1 D ASP 224 ? OD1 ? D ASP 205 OD1 
370 1 Y 1 D ASP 224 ? OD2 ? D ASP 205 OD2 
371 1 Y 1 D LYS 225 ? CG  ? D LYS 206 CG  
372 1 Y 1 D LYS 225 ? CD  ? D LYS 206 CD  
373 1 Y 1 D LYS 225 ? CE  ? D LYS 206 CE  
374 1 Y 1 D LYS 225 ? NZ  ? D LYS 206 NZ  
375 1 Y 1 D GLU 246 ? CG  ? D GLU 227 CG  
376 1 Y 1 D GLU 246 ? CD  ? D GLU 227 CD  
377 1 Y 1 D GLU 246 ? OE1 ? D GLU 227 OE1 
378 1 Y 1 D GLU 246 ? OE2 ? D GLU 227 OE2 
379 1 Y 1 D PHE 294 ? CG  ? D PHE 275 CG  
380 1 Y 1 D PHE 294 ? CD1 ? D PHE 275 CD1 
381 1 Y 1 D PHE 294 ? CD2 ? D PHE 275 CD2 
382 1 Y 1 D PHE 294 ? CE1 ? D PHE 275 CE1 
383 1 Y 1 D PHE 294 ? CE2 ? D PHE 275 CE2 
384 1 Y 1 D PHE 294 ? CZ  ? D PHE 275 CZ  
385 1 Y 1 D ILE 295 ? CG1 ? D ILE 276 CG1 
386 1 Y 1 D ILE 295 ? CG2 ? D ILE 276 CG2 
387 1 Y 1 D ILE 295 ? CD1 ? D ILE 276 CD1 
388 1 Y 1 D GLN 298 ? CG  ? D GLN 279 CG  
389 1 Y 1 D GLN 298 ? CD  ? D GLN 279 CD  
390 1 Y 1 D GLN 298 ? OE1 ? D GLN 279 OE1 
391 1 Y 1 D GLN 298 ? NE2 ? D GLN 279 NE2 
392 1 Y 1 D GLN 306 ? CG  ? D GLN 287 CG  
393 1 Y 1 D GLN 306 ? CD  ? D GLN 287 CD  
394 1 Y 1 D GLN 306 ? OE1 ? D GLN 287 OE1 
395 1 Y 1 D GLN 306 ? NE2 ? D GLN 287 NE2 
396 1 Y 1 D ARG 309 ? CG  ? D ARG 290 CG  
397 1 Y 1 D ARG 309 ? CD  ? D ARG 290 CD  
398 1 Y 1 D ARG 309 ? NE  ? D ARG 290 NE  
399 1 Y 1 D ARG 309 ? CZ  ? D ARG 290 CZ  
400 1 Y 1 D ARG 309 ? NH1 ? D ARG 290 NH1 
401 1 Y 1 D ARG 309 ? NH2 ? D ARG 290 NH2 
402 1 Y 1 D LYS 312 ? CG  ? D LYS 293 CG  
403 1 Y 1 D LYS 312 ? CD  ? D LYS 293 CD  
404 1 Y 1 D LYS 312 ? CE  ? D LYS 293 CE  
405 1 Y 1 D LYS 312 ? NZ  ? D LYS 293 NZ  
406 1 Y 1 D ASP 313 ? CG  ? D ASP 294 CG  
407 1 Y 1 D ASP 313 ? OD1 ? D ASP 294 OD1 
408 1 Y 1 D ASP 313 ? OD2 ? D ASP 294 OD2 
409 1 Y 1 D LYS 316 ? CG  ? D LYS 297 CG  
410 1 Y 1 D LYS 316 ? CD  ? D LYS 297 CD  
411 1 Y 1 D LYS 316 ? CE  ? D LYS 297 CE  
412 1 Y 1 D LYS 316 ? NZ  ? D LYS 297 NZ  
413 1 Y 1 D LYS 357 ? CG  ? D LYS 338 CG  
414 1 Y 1 D LYS 357 ? CD  ? D LYS 338 CD  
415 1 Y 1 D LYS 357 ? CE  ? D LYS 338 CE  
416 1 Y 1 D LYS 357 ? NZ  ? D LYS 338 NZ  
417 1 Y 1 D LYS 374 ? CG  ? D LYS 355 CG  
418 1 Y 1 D LYS 374 ? CD  ? D LYS 355 CD  
419 1 Y 1 D LYS 374 ? CE  ? D LYS 355 CE  
420 1 Y 1 D LYS 374 ? NZ  ? D LYS 355 NZ  
421 1 Y 1 D ARG 379 ? CG  ? D ARG 360 CG  
422 1 Y 1 D ARG 379 ? CD  ? D ARG 360 CD  
423 1 Y 1 D ARG 379 ? NE  ? D ARG 360 NE  
424 1 Y 1 D ARG 379 ? CZ  ? D ARG 360 CZ  
425 1 Y 1 D ARG 379 ? NH1 ? D ARG 360 NH1 
426 1 Y 1 D ARG 379 ? NH2 ? D ARG 360 NH2 
427 1 Y 1 D GLU 386 ? CG  ? D GLU 367 CG  
428 1 Y 1 D GLU 386 ? CD  ? D GLU 367 CD  
429 1 Y 1 D GLU 386 ? OE1 ? D GLU 367 OE1 
430 1 Y 1 D GLU 386 ? OE2 ? D GLU 367 OE2 
431 1 Y 1 D GLU 388 ? CG  ? D GLU 369 CG  
432 1 Y 1 D GLU 388 ? CD  ? D GLU 369 CD  
433 1 Y 1 D GLU 388 ? OE1 ? D GLU 369 OE1 
434 1 Y 1 D GLU 388 ? OE2 ? D GLU 369 OE2 
435 1 Y 1 D ARG 390 ? CG  ? D ARG 371 CG  
436 1 Y 1 D ARG 390 ? CD  ? D ARG 371 CD  
437 1 Y 1 D ARG 390 ? NE  ? D ARG 371 NE  
438 1 Y 1 D ARG 390 ? CZ  ? D ARG 371 CZ  
439 1 Y 1 D ARG 390 ? NH1 ? D ARG 371 NH1 
440 1 Y 1 D ARG 390 ? NH2 ? D ARG 371 NH2 
441 1 Y 1 D ARG 392 ? CG  ? D ARG 373 CG  
442 1 Y 1 D ARG 392 ? CD  ? D ARG 373 CD  
443 1 Y 1 D ARG 392 ? NE  ? D ARG 373 NE  
444 1 Y 1 D ARG 392 ? CZ  ? D ARG 373 CZ  
445 1 Y 1 D ARG 392 ? NH1 ? D ARG 373 NH1 
446 1 Y 1 D ARG 392 ? NH2 ? D ARG 373 NH2 
447 1 Y 1 E LYS 63  ? CG  ? E LYS 44  CG  
448 1 Y 1 E LYS 63  ? CD  ? E LYS 44  CD  
449 1 Y 1 E LYS 63  ? CE  ? E LYS 44  CE  
450 1 Y 1 E LYS 63  ? NZ  ? E LYS 44  NZ  
451 1 Y 1 E ARG 85  ? CG  ? E ARG 66  CG  
452 1 Y 1 E ARG 85  ? CD  ? E ARG 66  CD  
453 1 Y 1 E ARG 85  ? NE  ? E ARG 66  NE  
454 1 Y 1 E ARG 85  ? CZ  ? E ARG 66  CZ  
455 1 Y 1 E ARG 85  ? NH1 ? E ARG 66  NH1 
456 1 Y 1 E ARG 85  ? NH2 ? E ARG 66  NH2 
457 1 Y 1 E ARG 99  ? CG  ? E ARG 80  CG  
458 1 Y 1 E ARG 99  ? CD  ? E ARG 80  CD  
459 1 Y 1 E ARG 99  ? NE  ? E ARG 80  NE  
460 1 Y 1 E ARG 99  ? CZ  ? E ARG 80  CZ  
461 1 Y 1 E ARG 99  ? NH1 ? E ARG 80  NH1 
462 1 Y 1 E ARG 99  ? NH2 ? E ARG 80  NH2 
463 1 Y 1 E ASN 103 ? CG  ? E ASN 84  CG  
464 1 Y 1 E ASN 103 ? OD1 ? E ASN 84  OD1 
465 1 Y 1 E ASN 103 ? ND2 ? E ASN 84  ND2 
466 1 Y 1 E LYS 127 ? CG  ? E LYS 108 CG  
467 1 Y 1 E LYS 127 ? CD  ? E LYS 108 CD  
468 1 Y 1 E LYS 127 ? CE  ? E LYS 108 CE  
469 1 Y 1 E LYS 127 ? NZ  ? E LYS 108 NZ  
470 1 Y 1 E GLU 128 ? CG  ? E GLU 109 CG  
471 1 Y 1 E GLU 128 ? CD  ? E GLU 109 CD  
472 1 Y 1 E GLU 128 ? OE1 ? E GLU 109 OE1 
473 1 Y 1 E GLU 128 ? OE2 ? E GLU 109 OE2 
474 1 Y 1 E GLN 134 ? CG  ? E GLN 115 CG  
475 1 Y 1 E GLN 134 ? CD  ? E GLN 115 CD  
476 1 Y 1 E GLN 134 ? OE1 ? E GLN 115 OE1 
477 1 Y 1 E GLN 134 ? NE2 ? E GLN 115 NE2 
478 1 Y 1 E LEU 137 ? CG  ? E LEU 118 CG  
479 1 Y 1 E LEU 137 ? CD1 ? E LEU 118 CD1 
480 1 Y 1 E LEU 137 ? CD2 ? E LEU 118 CD2 
481 1 Y 1 E ARG 138 ? CG  ? E ARG 119 CG  
482 1 Y 1 E ARG 138 ? CD  ? E ARG 119 CD  
483 1 Y 1 E ARG 138 ? NE  ? E ARG 119 NE  
484 1 Y 1 E ARG 138 ? CZ  ? E ARG 119 CZ  
485 1 Y 1 E ARG 138 ? NH1 ? E ARG 119 NH1 
486 1 Y 1 E ARG 138 ? NH2 ? E ARG 119 NH2 
487 1 Y 1 E GLU 143 ? CG  ? E GLU 124 CG  
488 1 Y 1 E GLU 143 ? CD  ? E GLU 124 CD  
489 1 Y 1 E GLU 143 ? OE1 ? E GLU 124 OE1 
490 1 Y 1 E GLU 143 ? OE2 ? E GLU 124 OE2 
491 1 Y 1 E LEU 144 ? CG  ? E LEU 125 CG  
492 1 Y 1 E LEU 144 ? CD1 ? E LEU 125 CD1 
493 1 Y 1 E LEU 144 ? CD2 ? E LEU 125 CD2 
494 1 Y 1 E ARG 146 ? CG  ? E ARG 127 CG  
495 1 Y 1 E ARG 146 ? CD  ? E ARG 127 CD  
496 1 Y 1 E ARG 146 ? NE  ? E ARG 127 NE  
497 1 Y 1 E ARG 146 ? CZ  ? E ARG 127 CZ  
498 1 Y 1 E ARG 146 ? NH1 ? E ARG 127 NH1 
499 1 Y 1 E ARG 146 ? NH2 ? E ARG 127 NH2 
500 1 Y 1 E LYS 147 ? CG  ? E LYS 128 CG  
501 1 Y 1 E LYS 147 ? CD  ? E LYS 128 CD  
502 1 Y 1 E LYS 147 ? CE  ? E LYS 128 CE  
503 1 Y 1 E LYS 147 ? NZ  ? E LYS 128 NZ  
504 1 Y 1 E LYS 148 ? CG  ? E LYS 129 CG  
505 1 Y 1 E LYS 148 ? CD  ? E LYS 129 CD  
506 1 Y 1 E LYS 148 ? CE  ? E LYS 129 CE  
507 1 Y 1 E LYS 148 ? NZ  ? E LYS 129 NZ  
508 1 Y 1 E GLN 150 ? CG  ? E GLN 131 CG  
509 1 Y 1 E GLN 150 ? CD  ? E GLN 131 CD  
510 1 Y 1 E GLN 150 ? OE1 ? E GLN 131 OE1 
511 1 Y 1 E GLN 150 ? NE2 ? E GLN 131 NE2 
512 1 Y 1 E LEU 151 ? CG  ? E LEU 132 CG  
513 1 Y 1 E LEU 151 ? CD1 ? E LEU 132 CD1 
514 1 Y 1 E LEU 151 ? CD2 ? E LEU 132 CD2 
515 1 Y 1 E GLU 160 ? CG  ? E GLU 141 CG  
516 1 Y 1 E GLU 160 ? CD  ? E GLU 141 CD  
517 1 Y 1 E GLU 160 ? OE1 ? E GLU 141 OE1 
518 1 Y 1 E GLU 160 ? OE2 ? E GLU 141 OE2 
519 1 Y 1 E LYS 196 ? CG  ? E LYS 177 CG  
520 1 Y 1 E LYS 196 ? CD  ? E LYS 177 CD  
521 1 Y 1 E LYS 196 ? CE  ? E LYS 177 CE  
522 1 Y 1 E LYS 196 ? NZ  ? E LYS 177 NZ  
523 1 Y 1 E GLU 201 ? CG  ? E GLU 182 CG  
524 1 Y 1 E GLU 201 ? CD  ? E GLU 182 CD  
525 1 Y 1 E GLU 201 ? OE1 ? E GLU 182 OE1 
526 1 Y 1 E GLU 201 ? OE2 ? E GLU 182 OE2 
527 1 Y 1 E GLN 219 ? CG  ? E GLN 200 CG  
528 1 Y 1 E GLN 219 ? CD  ? E GLN 200 CD  
529 1 Y 1 E GLN 219 ? OE1 ? E GLN 200 OE1 
530 1 Y 1 E GLN 219 ? NE2 ? E GLN 200 NE2 
531 1 Y 1 E LYS 220 ? CG  ? E LYS 201 CG  
532 1 Y 1 E LYS 220 ? CD  ? E LYS 201 CD  
533 1 Y 1 E LYS 220 ? CE  ? E LYS 201 CE  
534 1 Y 1 E LYS 220 ? NZ  ? E LYS 201 NZ  
535 1 Y 1 E GLU 246 ? CG  ? E GLU 227 CG  
536 1 Y 1 E GLU 246 ? CD  ? E GLU 227 CD  
537 1 Y 1 E GLU 246 ? OE1 ? E GLU 227 OE1 
538 1 Y 1 E GLU 246 ? OE2 ? E GLU 227 OE2 
539 1 Y 1 E ASP 297 ? CG  ? E ASP 278 CG  
540 1 Y 1 E ASP 297 ? OD1 ? E ASP 278 OD1 
541 1 Y 1 E ASP 297 ? OD2 ? E ASP 278 OD2 
542 1 Y 1 E GLN 306 ? CG  ? E GLN 287 CG  
543 1 Y 1 E GLN 306 ? CD  ? E GLN 287 CD  
544 1 Y 1 E GLN 306 ? OE1 ? E GLN 287 OE1 
545 1 Y 1 E GLN 306 ? NE2 ? E GLN 287 NE2 
546 1 Y 1 E LYS 312 ? CG  ? E LYS 293 CG  
547 1 Y 1 E LYS 312 ? CD  ? E LYS 293 CD  
548 1 Y 1 E LYS 312 ? CE  ? E LYS 293 CE  
549 1 Y 1 E LYS 312 ? NZ  ? E LYS 293 NZ  
550 1 Y 1 E GLU 328 ? CG  ? E GLU 309 CG  
551 1 Y 1 E GLU 328 ? CD  ? E GLU 309 CD  
552 1 Y 1 E GLU 328 ? OE1 ? E GLU 309 OE1 
553 1 Y 1 E GLU 328 ? OE2 ? E GLU 309 OE2 
554 1 Y 1 E MET 362 ? CG  ? E MET 343 CG  
555 1 Y 1 E MET 362 ? SD  ? E MET 343 SD  
556 1 Y 1 E MET 362 ? CE  ? E MET 343 CE  
557 1 Y 1 E LYS 385 ? CG  ? E LYS 366 CG  
558 1 Y 1 E LYS 385 ? CD  ? E LYS 366 CD  
559 1 Y 1 E LYS 385 ? CE  ? E LYS 366 CE  
560 1 Y 1 E LYS 385 ? NZ  ? E LYS 366 NZ  
561 1 Y 1 E GLU 388 ? CG  ? E GLU 369 CG  
562 1 Y 1 E GLU 388 ? CD  ? E GLU 369 CD  
563 1 Y 1 E GLU 388 ? OE1 ? E GLU 369 OE1 
564 1 Y 1 E GLU 388 ? OE2 ? E GLU 369 OE2 
565 1 Y 1 E ARG 390 ? CG  ? E ARG 371 CG  
566 1 Y 1 E ARG 390 ? CD  ? E ARG 371 CD  
567 1 Y 1 E ARG 390 ? NE  ? E ARG 371 NE  
568 1 Y 1 E ARG 390 ? CZ  ? E ARG 371 CZ  
569 1 Y 1 E ARG 390 ? NH1 ? E ARG 371 NH1 
570 1 Y 1 E ARG 390 ? NH2 ? E ARG 371 NH2 
571 1 Y 1 F GLU 37  ? CG  ? F GLU 18  CG  
572 1 Y 1 F GLU 37  ? CD  ? F GLU 18  CD  
573 1 Y 1 F GLU 37  ? OE1 ? F GLU 18  OE1 
574 1 Y 1 F GLU 37  ? OE2 ? F GLU 18  OE2 
575 1 Y 1 F LYS 63  ? CG  ? F LYS 44  CG  
576 1 Y 1 F LYS 63  ? CD  ? F LYS 44  CD  
577 1 Y 1 F LYS 63  ? CE  ? F LYS 44  CE  
578 1 Y 1 F LYS 63  ? NZ  ? F LYS 44  NZ  
579 1 Y 1 F GLU 64  ? CG  ? F GLU 45  CG  
580 1 Y 1 F GLU 64  ? CD  ? F GLU 45  CD  
581 1 Y 1 F GLU 64  ? OE1 ? F GLU 45  OE1 
582 1 Y 1 F GLU 64  ? OE2 ? F GLU 45  OE2 
583 1 Y 1 F GLU 67  ? CG  ? F GLU 48  CG  
584 1 Y 1 F GLU 67  ? CD  ? F GLU 48  CD  
585 1 Y 1 F GLU 67  ? OE1 ? F GLU 48  OE1 
586 1 Y 1 F GLU 67  ? OE2 ? F GLU 48  OE2 
587 1 Y 1 F ARG 85  ? CG  ? F ARG 66  CG  
588 1 Y 1 F ARG 85  ? CD  ? F ARG 66  CD  
589 1 Y 1 F ARG 85  ? NE  ? F ARG 66  NE  
590 1 Y 1 F ARG 85  ? CZ  ? F ARG 66  CZ  
591 1 Y 1 F ARG 85  ? NH1 ? F ARG 66  NH1 
592 1 Y 1 F ARG 85  ? NH2 ? F ARG 66  NH2 
593 1 Y 1 F GLU 97  ? CG  ? F GLU 78  CG  
594 1 Y 1 F GLU 97  ? CD  ? F GLU 78  CD  
595 1 Y 1 F GLU 97  ? OE1 ? F GLU 78  OE1 
596 1 Y 1 F GLU 97  ? OE2 ? F GLU 78  OE2 
597 1 Y 1 F LYS 107 ? CG  ? F LYS 88  CG  
598 1 Y 1 F LYS 107 ? CD  ? F LYS 88  CD  
599 1 Y 1 F LYS 107 ? CE  ? F LYS 88  CE  
600 1 Y 1 F LYS 107 ? NZ  ? F LYS 88  NZ  
601 1 Y 1 F LYS 127 ? CG  ? F LYS 108 CG  
602 1 Y 1 F LYS 127 ? CD  ? F LYS 108 CD  
603 1 Y 1 F LYS 127 ? CE  ? F LYS 108 CE  
604 1 Y 1 F LYS 127 ? NZ  ? F LYS 108 NZ  
605 1 Y 1 F GLN 134 ? CG  ? F GLN 115 CG  
606 1 Y 1 F GLN 134 ? CD  ? F GLN 115 CD  
607 1 Y 1 F GLN 134 ? OE1 ? F GLN 115 OE1 
608 1 Y 1 F GLN 134 ? NE2 ? F GLN 115 NE2 
609 1 Y 1 F ARG 138 ? CG  ? F ARG 119 CG  
610 1 Y 1 F ARG 138 ? CD  ? F ARG 119 CD  
611 1 Y 1 F ARG 138 ? NE  ? F ARG 119 NE  
612 1 Y 1 F ARG 138 ? CZ  ? F ARG 119 CZ  
613 1 Y 1 F ARG 138 ? NH1 ? F ARG 119 NH1 
614 1 Y 1 F ARG 138 ? NH2 ? F ARG 119 NH2 
615 1 Y 1 F GLU 143 ? CG  ? F GLU 124 CG  
616 1 Y 1 F GLU 143 ? CD  ? F GLU 124 CD  
617 1 Y 1 F GLU 143 ? OE1 ? F GLU 124 OE1 
618 1 Y 1 F GLU 143 ? OE2 ? F GLU 124 OE2 
619 1 Y 1 F ASP 145 ? CG  ? F ASP 126 CG  
620 1 Y 1 F ASP 145 ? OD1 ? F ASP 126 OD1 
621 1 Y 1 F ASP 145 ? OD2 ? F ASP 126 OD2 
622 1 Y 1 F ARG 146 ? CG  ? F ARG 127 CG  
623 1 Y 1 F ARG 146 ? CD  ? F ARG 127 CD  
624 1 Y 1 F ARG 146 ? NE  ? F ARG 127 NE  
625 1 Y 1 F ARG 146 ? CZ  ? F ARG 127 CZ  
626 1 Y 1 F ARG 146 ? NH1 ? F ARG 127 NH1 
627 1 Y 1 F ARG 146 ? NH2 ? F ARG 127 NH2 
628 1 Y 1 F LYS 147 ? CG  ? F LYS 128 CG  
629 1 Y 1 F LYS 147 ? CD  ? F LYS 128 CD  
630 1 Y 1 F LYS 147 ? CE  ? F LYS 128 CE  
631 1 Y 1 F LYS 147 ? NZ  ? F LYS 128 NZ  
632 1 Y 1 F LYS 148 ? CG  ? F LYS 129 CG  
633 1 Y 1 F LYS 148 ? CD  ? F LYS 129 CD  
634 1 Y 1 F LYS 148 ? CE  ? F LYS 129 CE  
635 1 Y 1 F LYS 148 ? NZ  ? F LYS 129 NZ  
636 1 Y 1 F GLN 150 ? CG  ? F GLN 131 CG  
637 1 Y 1 F GLN 150 ? CD  ? F GLN 131 CD  
638 1 Y 1 F GLN 150 ? OE1 ? F GLN 131 OE1 
639 1 Y 1 F GLN 150 ? NE2 ? F GLN 131 NE2 
640 1 Y 1 F LEU 151 ? CG  ? F LEU 132 CG  
641 1 Y 1 F LEU 151 ? CD1 ? F LEU 132 CD1 
642 1 Y 1 F LEU 151 ? CD2 ? F LEU 132 CD2 
643 1 Y 1 F MET 152 ? CG  ? F MET 133 CG  
644 1 Y 1 F MET 152 ? SD  ? F MET 133 SD  
645 1 Y 1 F MET 152 ? CE  ? F MET 133 CE  
646 1 Y 1 F GLU 160 ? CG  ? F GLU 141 CG  
647 1 Y 1 F GLU 160 ? CD  ? F GLU 141 CD  
648 1 Y 1 F GLU 160 ? OE1 ? F GLU 141 OE1 
649 1 Y 1 F GLU 160 ? OE2 ? F GLU 141 OE2 
650 1 Y 1 F LYS 171 ? CG  ? F LYS 152 CG  
651 1 Y 1 F LYS 171 ? CD  ? F LYS 152 CD  
652 1 Y 1 F LYS 171 ? CE  ? F LYS 152 CE  
653 1 Y 1 F LYS 171 ? NZ  ? F LYS 152 NZ  
654 1 Y 1 F GLN 188 ? CG  ? F GLN 169 CG  
655 1 Y 1 F GLN 188 ? CD  ? F GLN 169 CD  
656 1 Y 1 F GLN 188 ? OE1 ? F GLN 169 OE1 
657 1 Y 1 F GLN 188 ? NE2 ? F GLN 169 NE2 
658 1 Y 1 F GLN 192 ? CG  ? F GLN 173 CG  
659 1 Y 1 F GLN 192 ? CD  ? F GLN 173 CD  
660 1 Y 1 F GLN 192 ? OE1 ? F GLN 173 OE1 
661 1 Y 1 F GLN 192 ? NE2 ? F GLN 173 NE2 
662 1 Y 1 F LYS 196 ? CG  ? F LYS 177 CG  
663 1 Y 1 F LYS 196 ? CD  ? F LYS 177 CD  
664 1 Y 1 F LYS 196 ? CE  ? F LYS 177 CE  
665 1 Y 1 F LYS 196 ? NZ  ? F LYS 177 NZ  
666 1 Y 1 F GLU 201 ? CG  ? F GLU 182 CG  
667 1 Y 1 F GLU 201 ? CD  ? F GLU 182 CD  
668 1 Y 1 F GLU 201 ? OE1 ? F GLU 182 OE1 
669 1 Y 1 F GLU 201 ? OE2 ? F GLU 182 OE2 
670 1 Y 1 F LYS 220 ? CG  ? F LYS 201 CG  
671 1 Y 1 F LYS 220 ? CD  ? F LYS 201 CD  
672 1 Y 1 F LYS 220 ? CE  ? F LYS 201 CE  
673 1 Y 1 F LYS 220 ? NZ  ? F LYS 201 NZ  
674 1 Y 1 F ASP 237 ? CG  ? F ASP 218 CG  
675 1 Y 1 F ASP 237 ? OD1 ? F ASP 218 OD1 
676 1 Y 1 F ASP 237 ? OD2 ? F ASP 218 OD2 
677 1 Y 1 F GLU 254 ? CG  ? F GLU 235 CG  
678 1 Y 1 F GLU 254 ? CD  ? F GLU 235 CD  
679 1 Y 1 F GLU 254 ? OE1 ? F GLU 235 OE1 
680 1 Y 1 F GLU 254 ? OE2 ? F GLU 235 OE2 
681 1 Y 1 F ASP 296 ? CG  ? F ASP 277 CG  
682 1 Y 1 F ASP 296 ? OD1 ? F ASP 277 OD1 
683 1 Y 1 F ASP 296 ? OD2 ? F ASP 277 OD2 
684 1 Y 1 F ASP 297 ? CG  ? F ASP 278 CG  
685 1 Y 1 F ASP 297 ? OD1 ? F ASP 278 OD1 
686 1 Y 1 F ASP 297 ? OD2 ? F ASP 278 OD2 
687 1 Y 1 F GLN 298 ? CG  ? F GLN 279 CG  
688 1 Y 1 F GLN 298 ? CD  ? F GLN 279 CD  
689 1 Y 1 F GLN 298 ? OE1 ? F GLN 279 OE1 
690 1 Y 1 F GLN 298 ? NE2 ? F GLN 279 NE2 
691 1 Y 1 F ARG 301 ? CG  ? F ARG 282 CG  
692 1 Y 1 F ARG 301 ? CD  ? F ARG 282 CD  
693 1 Y 1 F ARG 301 ? NE  ? F ARG 282 NE  
694 1 Y 1 F ARG 301 ? CZ  ? F ARG 282 CZ  
695 1 Y 1 F ARG 301 ? NH1 ? F ARG 282 NH1 
696 1 Y 1 F ARG 301 ? NH2 ? F ARG 282 NH2 
697 1 Y 1 F LYS 302 ? CG  ? F LYS 283 CG  
698 1 Y 1 F LYS 302 ? CD  ? F LYS 283 CD  
699 1 Y 1 F LYS 302 ? CE  ? F LYS 283 CE  
700 1 Y 1 F LYS 302 ? NZ  ? F LYS 283 NZ  
701 1 Y 1 F ARG 309 ? CG  ? F ARG 290 CG  
702 1 Y 1 F ARG 309 ? CD  ? F ARG 290 CD  
703 1 Y 1 F ARG 309 ? NE  ? F ARG 290 NE  
704 1 Y 1 F ARG 309 ? CZ  ? F ARG 290 CZ  
705 1 Y 1 F ARG 309 ? NH1 ? F ARG 290 NH1 
706 1 Y 1 F ARG 309 ? NH2 ? F ARG 290 NH2 
707 1 Y 1 F LYS 312 ? CG  ? F LYS 293 CG  
708 1 Y 1 F LYS 312 ? CD  ? F LYS 293 CD  
709 1 Y 1 F LYS 312 ? CE  ? F LYS 293 CE  
710 1 Y 1 F LYS 312 ? NZ  ? F LYS 293 NZ  
711 1 Y 1 F ARG 339 ? CG  ? F ARG 320 CG  
712 1 Y 1 F ARG 339 ? CD  ? F ARG 320 CD  
713 1 Y 1 F ARG 339 ? NE  ? F ARG 320 NE  
714 1 Y 1 F ARG 339 ? CZ  ? F ARG 320 CZ  
715 1 Y 1 F ARG 339 ? NH1 ? F ARG 320 NH1 
716 1 Y 1 F ARG 339 ? NH2 ? F ARG 320 NH2 
717 1 Y 1 F ASP 365 ? CG  ? F ASP 346 CG  
718 1 Y 1 F ASP 365 ? OD1 ? F ASP 346 OD1 
719 1 Y 1 F ASP 365 ? OD2 ? F ASP 346 OD2 
720 1 Y 1 F LYS 368 ? CG  ? F LYS 349 CG  
721 1 Y 1 F LYS 368 ? CD  ? F LYS 349 CD  
722 1 Y 1 F LYS 368 ? CE  ? F LYS 349 CE  
723 1 Y 1 F LYS 368 ? NZ  ? F LYS 349 NZ  
724 1 Y 1 F GLU 383 ? CG  ? F GLU 364 CG  
725 1 Y 1 F GLU 383 ? CD  ? F GLU 364 CD  
726 1 Y 1 F GLU 383 ? OE1 ? F GLU 364 OE1 
727 1 Y 1 F GLU 383 ? OE2 ? F GLU 364 OE2 
728 1 Y 1 F GLU 386 ? CG  ? F GLU 367 CG  
729 1 Y 1 F GLU 386 ? CD  ? F GLU 367 CD  
730 1 Y 1 F GLU 386 ? OE1 ? F GLU 367 OE1 
731 1 Y 1 F GLU 386 ? OE2 ? F GLU 367 OE2 
732 1 Y 1 F GLU 388 ? CG  ? F GLU 369 CG  
733 1 Y 1 F GLU 388 ? CD  ? F GLU 369 CD  
734 1 Y 1 F GLU 388 ? OE1 ? F GLU 369 OE1 
735 1 Y 1 F GLU 388 ? OE2 ? F GLU 369 OE2 
736 1 Y 1 F ARG 390 ? CG  ? F ARG 371 CG  
737 1 Y 1 F ARG 390 ? CD  ? F ARG 371 CD  
738 1 Y 1 F ARG 390 ? NE  ? F ARG 371 NE  
739 1 Y 1 F ARG 390 ? CZ  ? F ARG 371 CZ  
740 1 Y 1 F ARG 390 ? NH1 ? F ARG 371 NH1 
741 1 Y 1 F ARG 390 ? NH2 ? F ARG 371 NH2 
742 1 Y 1 F ARG 392 ? CG  ? F ARG 373 CG  
743 1 Y 1 F ARG 392 ? CD  ? F ARG 373 CD  
744 1 Y 1 F ARG 392 ? NE  ? F ARG 373 NE  
745 1 Y 1 F ARG 392 ? CZ  ? F ARG 373 CZ  
746 1 Y 1 F ARG 392 ? NH1 ? F ARG 373 NH1 
747 1 Y 1 F ARG 392 ? NH2 ? F ARG 373 NH2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(1.20.1_4487: ???)' 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .                    2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   95.49 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8RG3 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     91.841 
_cell.length_a_esd                 ? 
_cell.length_b                     81.897 
_cell.length_b_esd                 ? 
_cell.length_c                     160.310 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8RG3 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8RG3 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.43 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          49.29 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '100 mM HEPES pH 7.5 10% w/v PEG 8000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-01-25 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9795 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I24' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9795 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I24 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          38.16 
_reflns.entry_id                                       8RG3 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.5 
_reflns.d_resolution_low                               91.42 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     460909 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.87 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.23 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.1536 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.994 
_reflns.pdbx_CC_star                                   0.999 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.1382 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.5 
_reflns_shell.d_res_low                                     91.42 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             460909 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.994 
_reflns_shell.pdbx_CC_star                                  0.999 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.1382 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8RG3 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.50 
_refine.ls_d_res_low                             91.42 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     159299 
_refine.ls_number_reflns_R_free                  3858 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.73 
_refine.ls_percent_reflns_R_free                 2.42 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2044 
_refine.ls_R_factor_R_free                       0.2529 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2032 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 28.18 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.36 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.50 
_refine_hist.d_res_low                        91.42 
_refine_hist.number_atoms_solvent             166 
_refine_hist.number_atoms_total               16873 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        16695 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         12 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.012 ? 1723 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.191 ? 2338 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 6.261 ? 2315 ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.054 ? 2441 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.011 ? 3007 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.50 2.53  . . 131 5211 93.00  . . . . 0.3471 . . . . . . . . . . . 0.3648 
'X-RAY DIFFRACTION' 2.53 2.56  . . 139 5629 99.00  . . . . 0.3313 . . . . . . . . . . . 0.4109 
'X-RAY DIFFRACTION' 2.56 2.59  . . 137 5490 99.00  . . . . 0.3143 . . . . . . . . . . . 0.3171 
'X-RAY DIFFRACTION' 2.59 2.63  . . 140 5667 100.00 . . . . 0.30   . . . . . . . . . . . 0.30   
'X-RAY DIFFRACTION' 2.63 2.67  . . 135 5533 99.00  . . . . 0.2841 . . . . . . . . . . . 0.3250 
'X-RAY DIFFRACTION' 2.67 2.71  . . 142 5591 99.00  . . . . 0.2771 . . . . . . . . . . . 0.3515 
'X-RAY DIFFRACTION' 2.71 2.75  . . 139 5588 99.00  . . . . 0.2694 . . . . . . . . . . . 0.2891 
'X-RAY DIFFRACTION' 2.75 2.79  . . 142 5622 99.00  . . . . 0.2624 . . . . . . . . . . . 0.3464 
'X-RAY DIFFRACTION' 2.79 2.84  . . 135 5537 100.00 . . . . 0.2696 . . . . . . . . . . . 0.2719 
'X-RAY DIFFRACTION' 2.84 2.89  . . 140 5602 100.00 . . . . 0.2718 . . . . . . . . . . . 0.3055 
'X-RAY DIFFRACTION' 2.89 2.95  . . 141 5641 100.00 . . . . 0.2715 . . . . . . . . . . . 0.3611 
'X-RAY DIFFRACTION' 2.95 3.01  . . 140 5596 99.00  . . . . 0.2404 . . . . . . . . . . . 0.3226 
'X-RAY DIFFRACTION' 3.01 3.08  . . 137 5587 99.00  . . . . 0.2428 . . . . . . . . . . . 0.3278 
'X-RAY DIFFRACTION' 3.08 3.15  . . 140 5571 99.00  . . . . 0.2362 . . . . . . . . . . . 0.2678 
'X-RAY DIFFRACTION' 3.15 3.23  . . 135 5531 99.00  . . . . 0.2255 . . . . . . . . . . . 0.2811 
'X-RAY DIFFRACTION' 3.23 3.31  . . 141 5605 100.00 . . . . 0.2168 . . . . . . . . . . . 0.2425 
'X-RAY DIFFRACTION' 3.31 3.41  . . 138 5687 99.00  . . . . 0.2075 . . . . . . . . . . . 0.2781 
'X-RAY DIFFRACTION' 3.41 3.52  . . 138 5519 99.00  . . . . 0.2009 . . . . . . . . . . . 0.2451 
'X-RAY DIFFRACTION' 3.52 3.65  . . 140 5539 99.00  . . . . 0.1966 . . . . . . . . . . . 0.2553 
'X-RAY DIFFRACTION' 3.65 3.79  . . 135 5549 99.00  . . . . 0.1781 . . . . . . . . . . . 0.2150 
'X-RAY DIFFRACTION' 3.79 3.96  . . 135 5571 99.00  . . . . 0.1722 . . . . . . . . . . . 0.2200 
'X-RAY DIFFRACTION' 3.96 4.17  . . 140 5569 99.00  . . . . 0.1580 . . . . . . . . . . . 0.2222 
'X-RAY DIFFRACTION' 4.17 4.44  . . 137 5504 98.00  . . . . 0.1491 . . . . . . . . . . . 0.1820 
'X-RAY DIFFRACTION' 4.44 4.78  . . 135 5510 98.00  . . . . 0.1448 . . . . . . . . . . . 0.2132 
'X-RAY DIFFRACTION' 4.78 5.26  . . 139 5513 98.00  . . . . 0.1592 . . . . . . . . . . . 0.2133 
'X-RAY DIFFRACTION' 5.26 6.02  . . 135 5527 98.00  . . . . 0.1808 . . . . . . . . . . . 0.2347 
'X-RAY DIFFRACTION' 6.02 7.58  . . 139 5501 98.00  . . . . 0.1846 . . . . . . . . . . . 0.2879 
'X-RAY DIFFRACTION' 7.58 91.42 . . 133 5451 97.00  . . . . 0.1464 . . . . . . . . . . . 0.1595 
# 
_struct.entry_id                     8RG3 
_struct.title                        'Crystal structure of PbFucA from Planctomycetes bacterium K23_9 in P 1 21 1' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8RG3 
_struct_keywords.text            'Fucoidan, endo-fucoidanase, endo-fuconase, GH168, glycosyl hydrolase, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 2 ? 
H N N 2 ? 
I N N 2 ? 
J N N 3 ? 
K N N 3 ? 
L N N 3 ? 
M N N 3 ? 
N N N 3 ? 
O N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A517NMB4_9BACT 
_struct_ref.pdbx_db_accession          A0A517NMB4 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;DESHYPEFSWDTVPIAFHFGKSQGLLTKEEAEFVATRSNFICLEKGHATRTHGTTEAGIEAEARQLKNLNPKMKVIFYWN
TFLDYSMFAAHKEYAKHPQWWLRTTTGELDRKKGQLMRYDLSNAEFRNWWTNVAAKAVVDGTCDGVFMDAFPQIASQANR
KLWGDEKFEAIQQGLQDIIQETRQKIGDDKLIVYNGIRSTPDWSAGFDFAEYTDAAMIEHFGHFQSASKETMLRDILEMQ
RAAKAGKIVVLKGWAGFTFIDDQAMRKPLTQKRRVAKDSLKFPLACFLAGAQENCYFIYNWGYRMENGCLEWYPEFDKPL
GKPVGEMVRDGWKLSREYKHASVRVDLESKEAEIRWR
;
_struct_ref.pdbx_align_begin           36 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8RG3 A 17 ? 373 ? A0A517NMB4 36 ? 392 ? 36 392 
2 1 8RG3 B 17 ? 373 ? A0A517NMB4 36 ? 392 ? 36 392 
3 1 8RG3 C 17 ? 373 ? A0A517NMB4 36 ? 392 ? 36 392 
4 1 8RG3 D 17 ? 373 ? A0A517NMB4 36 ? 392 ? 36 392 
5 1 8RG3 E 17 ? 373 ? A0A517NMB4 36 ? 392 ? 36 392 
6 1 8RG3 F 17 ? 373 ? A0A517NMB4 36 ? 392 ? 36 392 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8RG3 MET A 1  ? UNP A0A517NMB4 ? ? 'initiating methionine' 20 1  
1 8RG3 HIS A 2  ? UNP A0A517NMB4 ? ? 'expression tag'        21 2  
1 8RG3 HIS A 3  ? UNP A0A517NMB4 ? ? 'expression tag'        22 3  
1 8RG3 HIS A 4  ? UNP A0A517NMB4 ? ? 'expression tag'        23 4  
1 8RG3 HIS A 5  ? UNP A0A517NMB4 ? ? 'expression tag'        24 5  
1 8RG3 HIS A 6  ? UNP A0A517NMB4 ? ? 'expression tag'        25 6  
1 8RG3 HIS A 7  ? UNP A0A517NMB4 ? ? 'expression tag'        26 7  
1 8RG3 GLU A 8  ? UNP A0A517NMB4 ? ? 'expression tag'        27 8  
1 8RG3 ASN A 9  ? UNP A0A517NMB4 ? ? 'expression tag'        28 9  
1 8RG3 LEU A 10 ? UNP A0A517NMB4 ? ? 'expression tag'        29 10 
1 8RG3 TYR A 11 ? UNP A0A517NMB4 ? ? 'expression tag'        30 11 
1 8RG3 PHE A 12 ? UNP A0A517NMB4 ? ? 'expression tag'        31 12 
1 8RG3 GLN A 13 ? UNP A0A517NMB4 ? ? 'expression tag'        32 13 
1 8RG3 GLY A 14 ? UNP A0A517NMB4 ? ? 'expression tag'        33 14 
1 8RG3 SER A 15 ? UNP A0A517NMB4 ? ? 'expression tag'        34 15 
1 8RG3 GLY A 16 ? UNP A0A517NMB4 ? ? 'expression tag'        35 16 
2 8RG3 MET B 1  ? UNP A0A517NMB4 ? ? 'initiating methionine' 20 17 
2 8RG3 HIS B 2  ? UNP A0A517NMB4 ? ? 'expression tag'        21 18 
2 8RG3 HIS B 3  ? UNP A0A517NMB4 ? ? 'expression tag'        22 19 
2 8RG3 HIS B 4  ? UNP A0A517NMB4 ? ? 'expression tag'        23 20 
2 8RG3 HIS B 5  ? UNP A0A517NMB4 ? ? 'expression tag'        24 21 
2 8RG3 HIS B 6  ? UNP A0A517NMB4 ? ? 'expression tag'        25 22 
2 8RG3 HIS B 7  ? UNP A0A517NMB4 ? ? 'expression tag'        26 23 
2 8RG3 GLU B 8  ? UNP A0A517NMB4 ? ? 'expression tag'        27 24 
2 8RG3 ASN B 9  ? UNP A0A517NMB4 ? ? 'expression tag'        28 25 
2 8RG3 LEU B 10 ? UNP A0A517NMB4 ? ? 'expression tag'        29 26 
2 8RG3 TYR B 11 ? UNP A0A517NMB4 ? ? 'expression tag'        30 27 
2 8RG3 PHE B 12 ? UNP A0A517NMB4 ? ? 'expression tag'        31 28 
2 8RG3 GLN B 13 ? UNP A0A517NMB4 ? ? 'expression tag'        32 29 
2 8RG3 GLY B 14 ? UNP A0A517NMB4 ? ? 'expression tag'        33 30 
2 8RG3 SER B 15 ? UNP A0A517NMB4 ? ? 'expression tag'        34 31 
2 8RG3 GLY B 16 ? UNP A0A517NMB4 ? ? 'expression tag'        35 32 
3 8RG3 MET C 1  ? UNP A0A517NMB4 ? ? 'initiating methionine' 20 33 
3 8RG3 HIS C 2  ? UNP A0A517NMB4 ? ? 'expression tag'        21 34 
3 8RG3 HIS C 3  ? UNP A0A517NMB4 ? ? 'expression tag'        22 35 
3 8RG3 HIS C 4  ? UNP A0A517NMB4 ? ? 'expression tag'        23 36 
3 8RG3 HIS C 5  ? UNP A0A517NMB4 ? ? 'expression tag'        24 37 
3 8RG3 HIS C 6  ? UNP A0A517NMB4 ? ? 'expression tag'        25 38 
3 8RG3 HIS C 7  ? UNP A0A517NMB4 ? ? 'expression tag'        26 39 
3 8RG3 GLU C 8  ? UNP A0A517NMB4 ? ? 'expression tag'        27 40 
3 8RG3 ASN C 9  ? UNP A0A517NMB4 ? ? 'expression tag'        28 41 
3 8RG3 LEU C 10 ? UNP A0A517NMB4 ? ? 'expression tag'        29 42 
3 8RG3 TYR C 11 ? UNP A0A517NMB4 ? ? 'expression tag'        30 43 
3 8RG3 PHE C 12 ? UNP A0A517NMB4 ? ? 'expression tag'        31 44 
3 8RG3 GLN C 13 ? UNP A0A517NMB4 ? ? 'expression tag'        32 45 
3 8RG3 GLY C 14 ? UNP A0A517NMB4 ? ? 'expression tag'        33 46 
3 8RG3 SER C 15 ? UNP A0A517NMB4 ? ? 'expression tag'        34 47 
3 8RG3 GLY C 16 ? UNP A0A517NMB4 ? ? 'expression tag'        35 48 
4 8RG3 MET D 1  ? UNP A0A517NMB4 ? ? 'initiating methionine' 20 49 
4 8RG3 HIS D 2  ? UNP A0A517NMB4 ? ? 'expression tag'        21 50 
4 8RG3 HIS D 3  ? UNP A0A517NMB4 ? ? 'expression tag'        22 51 
4 8RG3 HIS D 4  ? UNP A0A517NMB4 ? ? 'expression tag'        23 52 
4 8RG3 HIS D 5  ? UNP A0A517NMB4 ? ? 'expression tag'        24 53 
4 8RG3 HIS D 6  ? UNP A0A517NMB4 ? ? 'expression tag'        25 54 
4 8RG3 HIS D 7  ? UNP A0A517NMB4 ? ? 'expression tag'        26 55 
4 8RG3 GLU D 8  ? UNP A0A517NMB4 ? ? 'expression tag'        27 56 
4 8RG3 ASN D 9  ? UNP A0A517NMB4 ? ? 'expression tag'        28 57 
4 8RG3 LEU D 10 ? UNP A0A517NMB4 ? ? 'expression tag'        29 58 
4 8RG3 TYR D 11 ? UNP A0A517NMB4 ? ? 'expression tag'        30 59 
4 8RG3 PHE D 12 ? UNP A0A517NMB4 ? ? 'expression tag'        31 60 
4 8RG3 GLN D 13 ? UNP A0A517NMB4 ? ? 'expression tag'        32 61 
4 8RG3 GLY D 14 ? UNP A0A517NMB4 ? ? 'expression tag'        33 62 
4 8RG3 SER D 15 ? UNP A0A517NMB4 ? ? 'expression tag'        34 63 
4 8RG3 GLY D 16 ? UNP A0A517NMB4 ? ? 'expression tag'        35 64 
5 8RG3 MET E 1  ? UNP A0A517NMB4 ? ? 'initiating methionine' 20 65 
5 8RG3 HIS E 2  ? UNP A0A517NMB4 ? ? 'expression tag'        21 66 
5 8RG3 HIS E 3  ? UNP A0A517NMB4 ? ? 'expression tag'        22 67 
5 8RG3 HIS E 4  ? UNP A0A517NMB4 ? ? 'expression tag'        23 68 
5 8RG3 HIS E 5  ? UNP A0A517NMB4 ? ? 'expression tag'        24 69 
5 8RG3 HIS E 6  ? UNP A0A517NMB4 ? ? 'expression tag'        25 70 
5 8RG3 HIS E 7  ? UNP A0A517NMB4 ? ? 'expression tag'        26 71 
5 8RG3 GLU E 8  ? UNP A0A517NMB4 ? ? 'expression tag'        27 72 
5 8RG3 ASN E 9  ? UNP A0A517NMB4 ? ? 'expression tag'        28 73 
5 8RG3 LEU E 10 ? UNP A0A517NMB4 ? ? 'expression tag'        29 74 
5 8RG3 TYR E 11 ? UNP A0A517NMB4 ? ? 'expression tag'        30 75 
5 8RG3 PHE E 12 ? UNP A0A517NMB4 ? ? 'expression tag'        31 76 
5 8RG3 GLN E 13 ? UNP A0A517NMB4 ? ? 'expression tag'        32 77 
5 8RG3 GLY E 14 ? UNP A0A517NMB4 ? ? 'expression tag'        33 78 
5 8RG3 SER E 15 ? UNP A0A517NMB4 ? ? 'expression tag'        34 79 
5 8RG3 GLY E 16 ? UNP A0A517NMB4 ? ? 'expression tag'        35 80 
6 8RG3 MET F 1  ? UNP A0A517NMB4 ? ? 'initiating methionine' 20 81 
6 8RG3 HIS F 2  ? UNP A0A517NMB4 ? ? 'expression tag'        21 82 
6 8RG3 HIS F 3  ? UNP A0A517NMB4 ? ? 'expression tag'        22 83 
6 8RG3 HIS F 4  ? UNP A0A517NMB4 ? ? 'expression tag'        23 84 
6 8RG3 HIS F 5  ? UNP A0A517NMB4 ? ? 'expression tag'        24 85 
6 8RG3 HIS F 6  ? UNP A0A517NMB4 ? ? 'expression tag'        25 86 
6 8RG3 HIS F 7  ? UNP A0A517NMB4 ? ? 'expression tag'        26 87 
6 8RG3 GLU F 8  ? UNP A0A517NMB4 ? ? 'expression tag'        27 88 
6 8RG3 ASN F 9  ? UNP A0A517NMB4 ? ? 'expression tag'        28 89 
6 8RG3 LEU F 10 ? UNP A0A517NMB4 ? ? 'expression tag'        29 90 
6 8RG3 TYR F 11 ? UNP A0A517NMB4 ? ? 'expression tag'        30 91 
6 8RG3 PHE F 12 ? UNP A0A517NMB4 ? ? 'expression tag'        31 92 
6 8RG3 GLN F 13 ? UNP A0A517NMB4 ? ? 'expression tag'        32 93 
6 8RG3 GLY F 14 ? UNP A0A517NMB4 ? ? 'expression tag'        33 94 
6 8RG3 SER F 15 ? UNP A0A517NMB4 ? ? 'expression tag'        34 95 
6 8RG3 GLY F 16 ? UNP A0A517NMB4 ? ? 'expression tag'        35 96 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
3 author_defined_assembly ? monomeric 1 
4 author_defined_assembly ? monomeric 1 
5 author_defined_assembly ? monomeric 1 
6 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,G,J 
2 1 B,H,K 
3 1 C,I,L 
4 1 D,M   
5 1 E,N   
6 1 F,O   
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 43  ? SER A 54  ? THR A 62  SER A 73  1 ? 12 
HELX_P HELX_P2  AA2 ALA A 64  ? GLY A 69  ? ALA A 83  GLY A 88  1 ? 6  
HELX_P HELX_P3  AA3 THR A 70  ? ASN A 86  ? THR A 89  ASN A 105 1 ? 17 
HELX_P HELX_P4  AA4 PHE A 104 ? ALA A 111 ? PHE A 123 ALA A 130 1 ? 8  
HELX_P HELX_P5  AA5 LYS A 112 ? TRP A 117 ? LYS A 131 TRP A 136 5 ? 6  
HELX_P HELX_P6  AA6 ASN A 139 ? VAL A 155 ? ASN A 158 VAL A 174 1 ? 17 
HELX_P HELX_P7  AA7 ALA A 166 ? SER A 172 ? ALA A 185 SER A 191 1 ? 7  
HELX_P HELX_P8  AA8 ALA A 174 ? GLY A 180 ? ALA A 193 GLY A 199 1 ? 7  
HELX_P HELX_P9  AA9 GLY A 180 ? GLY A 203 ? GLY A 199 GLY A 222 1 ? 24 
HELX_P HELX_P10 AB1 HIS A 239 ? ALA A 243 ? HIS A 258 ALA A 262 5 ? 5  
HELX_P HELX_P11 AB2 SER A 244 ? ALA A 261 ? SER A 263 ALA A 280 1 ? 18 
HELX_P HELX_P12 AB3 ASP A 277 ? LYS A 283 ? ASP A 296 LYS A 302 1 ? 7  
HELX_P HELX_P13 AB4 PRO A 284 ? LEU A 296 ? PRO A 303 LEU A 315 1 ? 13 
HELX_P HELX_P14 AB5 LEU A 296 ? ALA A 307 ? LEU A 315 ALA A 326 1 ? 12 
HELX_P HELX_P15 AB6 TYR A 329 ? ASP A 333 ? TYR A 348 ASP A 352 5 ? 5  
HELX_P HELX_P16 AB7 THR B 43  ? THR B 52  ? THR B 62  THR B 71  1 ? 10 
HELX_P HELX_P17 AB8 ALA B 64  ? GLY B 69  ? ALA B 83  GLY B 88  1 ? 6  
HELX_P HELX_P18 AB9 THR B 70  ? ASN B 86  ? THR B 89  ASN B 105 1 ? 17 
HELX_P HELX_P19 AC1 ALA B 105 ? ALA B 111 ? ALA B 124 ALA B 130 1 ? 7  
HELX_P HELX_P20 AC2 ASN B 139 ? VAL B 155 ? ASN B 158 VAL B 174 1 ? 17 
HELX_P HELX_P21 AC3 ALA B 166 ? SER B 172 ? ALA B 185 SER B 191 1 ? 7  
HELX_P HELX_P22 AC4 GLN B 173 ? GLY B 203 ? GLN B 192 GLY B 222 1 ? 31 
HELX_P HELX_P23 AC5 SER B 244 ? ALA B 261 ? SER B 263 ALA B 280 1 ? 18 
HELX_P HELX_P24 AC6 ASP B 277 ? LYS B 283 ? ASP B 296 LYS B 302 1 ? 7  
HELX_P HELX_P25 AC7 PRO B 284 ? LEU B 296 ? PRO B 303 LEU B 315 1 ? 13 
HELX_P HELX_P26 AC8 LEU B 296 ? ALA B 307 ? LEU B 315 ALA B 326 1 ? 12 
HELX_P HELX_P27 AC9 TYR B 329 ? ASP B 333 ? TYR B 348 ASP B 352 5 ? 5  
HELX_P HELX_P28 AD1 THR C 43  ? SER C 54  ? THR C 62  SER C 73  1 ? 12 
HELX_P HELX_P29 AD2 ALA C 64  ? GLY C 69  ? ALA C 83  GLY C 88  1 ? 6  
HELX_P HELX_P30 AD3 THR C 70  ? ASN C 86  ? THR C 89  ASN C 105 1 ? 17 
HELX_P HELX_P31 AD4 ALA C 105 ? ALA C 111 ? ALA C 124 ALA C 130 1 ? 7  
HELX_P HELX_P32 AD5 ASN C 139 ? VAL C 155 ? ASN C 158 VAL C 174 1 ? 17 
HELX_P HELX_P33 AD6 ALA C 166 ? SER C 172 ? ALA C 185 SER C 191 1 ? 7  
HELX_P HELX_P34 AD7 ALA C 174 ? GLY C 180 ? ALA C 193 GLY C 199 1 ? 7  
HELX_P HELX_P35 AD8 GLY C 180 ? GLY C 203 ? GLY C 199 GLY C 222 1 ? 24 
HELX_P HELX_P36 AD9 HIS C 239 ? ALA C 243 ? HIS C 258 ALA C 262 5 ? 5  
HELX_P HELX_P37 AE1 SER C 244 ? ALA C 261 ? SER C 263 ALA C 280 1 ? 18 
HELX_P HELX_P38 AE2 ASP C 277 ? ARG C 282 ? ASP C 296 ARG C 301 1 ? 6  
HELX_P HELX_P39 AE3 PRO C 284 ? SER C 295 ? PRO C 303 SER C 314 1 ? 12 
HELX_P HELX_P40 AE4 LEU C 296 ? ALA C 307 ? LEU C 315 ALA C 326 1 ? 12 
HELX_P HELX_P41 AE5 TYR C 329 ? ASP C 333 ? TYR C 348 ASP C 352 5 ? 5  
HELX_P HELX_P42 AE6 THR D 43  ? SER D 54  ? THR D 62  SER D 73  1 ? 12 
HELX_P HELX_P43 AE7 ALA D 64  ? GLY D 69  ? ALA D 83  GLY D 88  1 ? 6  
HELX_P HELX_P44 AE8 THR D 70  ? ASN D 86  ? THR D 89  ASN D 105 1 ? 17 
HELX_P HELX_P45 AE9 PHE D 104 ? ALA D 111 ? PHE D 123 ALA D 130 1 ? 8  
HELX_P HELX_P46 AF1 LYS D 112 ? TRP D 117 ? LYS D 131 TRP D 136 5 ? 6  
HELX_P HELX_P47 AF2 LYS D 129 ? GLN D 131 ? LYS D 148 GLN D 150 5 ? 3  
HELX_P HELX_P48 AF3 ASN D 139 ? VAL D 155 ? ASN D 158 VAL D 174 1 ? 17 
HELX_P HELX_P49 AF4 ALA D 166 ? SER D 172 ? ALA D 185 SER D 191 1 ? 7  
HELX_P HELX_P50 AF5 ALA D 174 ? GLY D 180 ? ALA D 193 GLY D 199 1 ? 7  
HELX_P HELX_P51 AF6 GLY D 180 ? GLY D 203 ? GLY D 199 GLY D 222 1 ? 24 
HELX_P HELX_P52 AF7 HIS D 239 ? ALA D 243 ? HIS D 258 ALA D 262 5 ? 5  
HELX_P HELX_P53 AF8 SER D 244 ? ALA D 261 ? SER D 263 ALA D 280 1 ? 18 
HELX_P HELX_P54 AF9 THR D 274 ? MET D 281 ? THR D 293 MET D 300 1 ? 8  
HELX_P HELX_P55 AG1 PRO D 284 ? LEU D 296 ? PRO D 303 LEU D 315 1 ? 13 
HELX_P HELX_P56 AG2 LEU D 296 ? ALA D 307 ? LEU D 315 ALA D 326 1 ? 12 
HELX_P HELX_P57 AG3 TYR D 329 ? ASP D 333 ? TYR D 348 ASP D 352 5 ? 5  
HELX_P HELX_P58 AG4 THR E 43  ? SER E 54  ? THR E 62  SER E 73  1 ? 12 
HELX_P HELX_P59 AG5 ALA E 64  ? GLY E 69  ? ALA E 83  GLY E 88  1 ? 6  
HELX_P HELX_P60 AG6 THR E 70  ? ASN E 86  ? THR E 89  ASN E 105 1 ? 17 
HELX_P HELX_P61 AG7 ALA E 105 ? ALA E 111 ? ALA E 124 ALA E 130 1 ? 7  
HELX_P HELX_P62 AG8 LYS E 129 ? GLN E 131 ? LYS E 148 GLN E 150 5 ? 3  
HELX_P HELX_P63 AG9 ASN E 139 ? VAL E 155 ? ASN E 158 VAL E 174 1 ? 17 
HELX_P HELX_P64 AH1 ALA E 166 ? ALA E 171 ? ALA E 185 ALA E 190 1 ? 6  
HELX_P HELX_P65 AH2 GLN E 173 ? GLY E 180 ? GLN E 192 GLY E 199 1 ? 8  
HELX_P HELX_P66 AH3 GLY E 180 ? GLY E 203 ? GLY E 199 GLY E 222 1 ? 24 
HELX_P HELX_P67 AH4 HIS E 239 ? ALA E 243 ? HIS E 258 ALA E 262 5 ? 5  
HELX_P HELX_P68 AH5 SER E 244 ? ALA E 261 ? SER E 263 ALA E 280 1 ? 18 
HELX_P HELX_P69 AH6 GLN E 279 ? LYS E 283 ? GLN E 298 LYS E 302 5 ? 5  
HELX_P HELX_P70 AH7 PRO E 284 ? SER E 295 ? PRO E 303 SER E 314 1 ? 12 
HELX_P HELX_P71 AH8 LEU E 296 ? ALA E 307 ? LEU E 315 ALA E 326 1 ? 12 
HELX_P HELX_P72 AH9 TYR E 329 ? ASP E 333 ? TYR E 348 ASP E 352 5 ? 5  
HELX_P HELX_P73 AI1 THR F 43  ? THR F 52  ? THR F 62  THR F 71  1 ? 10 
HELX_P HELX_P74 AI2 ALA F 64  ? GLY F 69  ? ALA F 83  GLY F 88  1 ? 6  
HELX_P HELX_P75 AI3 THR F 70  ? ASN F 86  ? THR F 89  ASN F 105 1 ? 17 
HELX_P HELX_P76 AI4 ALA F 105 ? ALA F 111 ? ALA F 124 ALA F 130 1 ? 7  
HELX_P HELX_P77 AI5 ASN F 139 ? VAL F 155 ? ASN F 158 VAL F 174 1 ? 17 
HELX_P HELX_P78 AI6 ALA F 166 ? SER F 172 ? ALA F 185 SER F 191 1 ? 7  
HELX_P HELX_P79 AI7 ALA F 174 ? GLY F 203 ? ALA F 193 GLY F 222 1 ? 30 
HELX_P HELX_P80 AI8 SER F 244 ? ALA F 261 ? SER F 263 ALA F 280 1 ? 18 
HELX_P HELX_P81 AI9 ASP F 277 ? ARG F 282 ? ASP F 296 ARG F 301 1 ? 6  
HELX_P HELX_P82 AJ1 PRO F 284 ? SER F 295 ? PRO F 303 SER F 314 1 ? 12 
HELX_P HELX_P83 AJ2 LEU F 296 ? ALA F 307 ? LEU F 315 ALA F 326 1 ? 12 
HELX_P HELX_P84 AJ3 TYR F 329 ? ASP F 333 ? TYR F 348 ASP F 352 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASN 211 A . ? ASN 230 A GLY 212 A ? GLY 231 A 1 6.37  
2 ASN 211 B . ? ASN 230 B GLY 212 B ? GLY 231 B 1 -1.53 
3 ASN 211 C . ? ASN 230 C GLY 212 C ? GLY 231 C 1 -9.53 
4 ASN 211 D . ? ASN 230 D GLY 212 D ? GLY 231 D 1 1.48  
5 ASN 211 E . ? ASN 230 E GLY 212 E ? GLY 231 E 1 2.09  
6 ASN 211 F . ? ASN 230 F GLY 212 F ? GLY 231 F 1 -4.28 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 6 ? 
AA5 ? 8 ? 
AA6 ? 4 ? 
AA7 ? 6 ? 
AA8 ? 8 ? 
AA9 ? 2 ? 
AB1 ? 4 ? 
AB2 ? 8 ? 
AB3 ? 2 ? 
AB4 ? 2 ? 
AB5 ? 4 ? 
AB6 ? 6 ? 
AB7 ? 8 ? 
AB8 ? 2 ? 
AB9 ? 4 ? 
AC1 ? 8 ? 
AC2 ? 2 ? 
AC3 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA1 7 8 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA4 5 6 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? parallel      
AA5 3 4 ? parallel      
AA5 4 5 ? parallel      
AA5 5 6 ? parallel      
AA5 6 7 ? parallel      
AA5 7 8 ? parallel      
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? parallel      
AA7 3 4 ? parallel      
AA7 4 5 ? parallel      
AA7 5 6 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? parallel      
AA8 3 4 ? parallel      
AA8 4 5 ? parallel      
AA8 5 6 ? parallel      
AA8 6 7 ? parallel      
AA8 7 8 ? parallel      
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? parallel      
AB2 3 4 ? parallel      
AB2 4 5 ? parallel      
AB2 5 6 ? parallel      
AB2 6 7 ? parallel      
AB2 7 8 ? parallel      
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? parallel      
AB6 3 4 ? parallel      
AB6 4 5 ? parallel      
AB6 5 6 ? anti-parallel 
AB7 1 2 ? parallel      
AB7 2 3 ? parallel      
AB7 3 4 ? parallel      
AB7 4 5 ? parallel      
AB7 5 6 ? parallel      
AB7 6 7 ? parallel      
AB7 7 8 ? parallel      
AB8 1 2 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? parallel      
AC1 2 3 ? parallel      
AC1 3 4 ? parallel      
AC1 4 5 ? parallel      
AC1 5 6 ? parallel      
AC1 6 7 ? parallel      
AC1 7 8 ? parallel      
AC2 1 2 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 33  ? PHE A 35  ? PHE A 52  PHE A 54  
AA1 2 PHE A 56  ? LEU A 59  ? PHE A 75  LEU A 78  
AA1 3 LYS A 90  ? TYR A 94  ? LYS A 109 TYR A 113 
AA1 4 GLY A 161 ? MET A 164 ? GLY A 180 MET A 183 
AA1 5 LEU A 207 ? ILE A 213 ? LEU A 226 ILE A 232 
AA1 6 ALA A 231 ? ILE A 234 ? ALA A 250 ILE A 253 
AA1 7 ILE A 264 ? TRP A 270 ? ILE A 283 TRP A 289 
AA1 8 CYS A 311 ? ASN A 316 ? CYS A 330 ASN A 335 
AA2 1 ARG A 127 ? LYS A 128 ? ARG A 146 LYS A 147 
AA2 2 LEU A 132 ? MET A 133 ? LEU A 151 MET A 152 
AA3 1 VAL A 344 ? ASP A 346 ? VAL A 363 ASP A 365 
AA3 2 LYS A 349 ? TYR A 354 ? LYS A 368 TYR A 373 
AA3 3 ALA A 357 ? ASP A 362 ? ALA A 376 ASP A 381 
AA3 4 ALA A 368 ? TRP A 372 ? ALA A 387 TRP A 391 
AA4 1 PHE B 33  ? PHE B 35  ? PHE B 52  PHE B 54  
AA4 2 PHE B 56  ? LEU B 59  ? PHE B 75  LEU B 78  
AA4 3 LYS B 90  ? ASN B 96  ? LYS B 109 ASN B 115 
AA4 4 GLY B 161 ? ASP B 165 ? GLY B 180 ASP B 184 
AA4 5 LEU B 207 ? SER B 215 ? LEU B 226 SER B 234 
AA4 6 SER B 220 ? ALA B 221 ? SER B 239 ALA B 240 
AA5 1 PHE B 33  ? PHE B 35  ? PHE B 52  PHE B 54  
AA5 2 PHE B 56  ? LEU B 59  ? PHE B 75  LEU B 78  
AA5 3 LYS B 90  ? ASN B 96  ? LYS B 109 ASN B 115 
AA5 4 GLY B 161 ? ASP B 165 ? GLY B 180 ASP B 184 
AA5 5 LEU B 207 ? SER B 215 ? LEU B 226 SER B 234 
AA5 6 ALA B 231 ? ILE B 234 ? ALA B 250 ILE B 253 
AA5 7 ILE B 264 ? TRP B 270 ? ILE B 283 TRP B 289 
AA5 8 CYS B 311 ? ASN B 316 ? CYS B 330 ASN B 335 
AA6 1 VAL B 344 ? ASP B 346 ? VAL B 363 ASP B 365 
AA6 2 LYS B 349 ? TYR B 354 ? LYS B 368 TYR B 373 
AA6 3 ALA B 357 ? ASP B 362 ? ALA B 376 ASP B 381 
AA6 4 ALA B 368 ? TRP B 372 ? ALA B 387 TRP B 391 
AA7 1 PHE C 33  ? PHE C 35  ? PHE C 52  PHE C 54  
AA7 2 PHE C 56  ? LEU C 59  ? PHE C 75  LEU C 78  
AA7 3 LYS C 90  ? TYR C 94  ? LYS C 109 TYR C 113 
AA7 4 GLY C 161 ? MET C 164 ? GLY C 180 MET C 183 
AA7 5 LEU C 207 ? SER C 215 ? LEU C 226 SER C 234 
AA7 6 SER C 220 ? ALA C 221 ? SER C 239 ALA C 240 
AA8 1 PHE C 33  ? PHE C 35  ? PHE C 52  PHE C 54  
AA8 2 PHE C 56  ? LEU C 59  ? PHE C 75  LEU C 78  
AA8 3 LYS C 90  ? TYR C 94  ? LYS C 109 TYR C 113 
AA8 4 GLY C 161 ? MET C 164 ? GLY C 180 MET C 183 
AA8 5 LEU C 207 ? SER C 215 ? LEU C 226 SER C 234 
AA8 6 ALA C 231 ? ILE C 234 ? ALA C 250 ILE C 253 
AA8 7 ILE C 264 ? TRP C 270 ? ILE C 283 TRP C 289 
AA8 8 CYS C 311 ? ASN C 316 ? CYS C 330 ASN C 335 
AA9 1 ARG C 127 ? LYS C 128 ? ARG C 146 LYS C 147 
AA9 2 LEU C 132 ? MET C 133 ? LEU C 151 MET C 152 
AB1 1 VAL C 344 ? ASP C 346 ? VAL C 363 ASP C 365 
AB1 2 LYS C 349 ? TYR C 354 ? LYS C 368 TYR C 373 
AB1 3 ALA C 357 ? ASP C 362 ? ALA C 376 ASP C 381 
AB1 4 GLU C 367 ? TRP C 372 ? GLU C 386 TRP C 391 
AB2 1 PHE D 33  ? PHE D 35  ? PHE D 52  PHE D 54  
AB2 2 PHE D 56  ? LEU D 59  ? PHE D 75  LEU D 78  
AB2 3 LYS D 90  ? ASN D 96  ? LYS D 109 ASN D 115 
AB2 4 GLY D 161 ? ASP D 165 ? GLY D 180 ASP D 184 
AB2 5 LEU D 207 ? TYR D 210 ? LEU D 226 TYR D 229 
AB2 6 ALA D 231 ? ILE D 234 ? ALA D 250 ILE D 253 
AB2 7 ILE D 264 ? GLY D 269 ? ILE D 283 GLY D 288 
AB2 8 CYS D 311 ? TYR D 315 ? CYS D 330 TYR D 334 
AB3 1 ARG D 127 ? LYS D 128 ? ARG D 146 LYS D 147 
AB3 2 LEU D 132 ? MET D 133 ? LEU D 151 MET D 152 
AB4 1 ARG D 214 ? SER D 215 ? ARG D 233 SER D 234 
AB4 2 SER D 220 ? ALA D 221 ? SER D 239 ALA D 240 
AB5 1 VAL D 344 ? ASP D 346 ? VAL D 363 ASP D 365 
AB5 2 LYS D 349 ? TYR D 354 ? LYS D 368 TYR D 373 
AB5 3 ALA D 357 ? ASP D 362 ? ALA D 376 ASP D 381 
AB5 4 GLU D 367 ? TRP D 372 ? GLU D 386 TRP D 391 
AB6 1 PHE E 33  ? PHE E 35  ? PHE E 52  PHE E 54  
AB6 2 PHE E 56  ? LEU E 59  ? PHE E 75  LEU E 78  
AB6 3 LYS E 90  ? TYR E 94  ? LYS E 109 TYR E 113 
AB6 4 GLY E 161 ? ASP E 165 ? GLY E 180 ASP E 184 
AB6 5 LEU E 207 ? SER E 215 ? LEU E 226 SER E 234 
AB6 6 SER E 220 ? ALA E 221 ? SER E 239 ALA E 240 
AB7 1 PHE E 33  ? PHE E 35  ? PHE E 52  PHE E 54  
AB7 2 PHE E 56  ? LEU E 59  ? PHE E 75  LEU E 78  
AB7 3 LYS E 90  ? TYR E 94  ? LYS E 109 TYR E 113 
AB7 4 GLY E 161 ? ASP E 165 ? GLY E 180 ASP E 184 
AB7 5 LEU E 207 ? SER E 215 ? LEU E 226 SER E 234 
AB7 6 ALA E 231 ? ILE E 234 ? ALA E 250 ILE E 253 
AB7 7 ILE E 264 ? TRP E 270 ? ILE E 283 TRP E 289 
AB7 8 CYS E 311 ? ASN E 316 ? CYS E 330 ASN E 335 
AB8 1 ARG E 127 ? LYS E 128 ? ARG E 146 LYS E 147 
AB8 2 LEU E 132 ? MET E 133 ? LEU E 151 MET E 152 
AB9 1 VAL E 344 ? ASP E 346 ? VAL E 363 ASP E 365 
AB9 2 LYS E 349 ? TYR E 354 ? LYS E 368 TYR E 373 
AB9 3 ALA E 357 ? ASP E 362 ? ALA E 376 ASP E 381 
AB9 4 GLU E 367 ? TRP E 372 ? GLU E 386 TRP E 391 
AC1 1 PHE F 33  ? PHE F 35  ? PHE F 52  PHE F 54  
AC1 2 PHE F 56  ? LEU F 59  ? PHE F 75  LEU F 78  
AC1 3 LYS F 90  ? ASN F 96  ? LYS F 109 ASN F 115 
AC1 4 GLY F 161 ? ASP F 165 ? GLY F 180 ASP F 184 
AC1 5 LEU F 207 ? TYR F 210 ? LEU F 226 TYR F 229 
AC1 6 ALA F 231 ? ILE F 234 ? ALA F 250 ILE F 253 
AC1 7 ILE F 264 ? TRP F 270 ? ILE F 283 TRP F 289 
AC1 8 CYS F 311 ? ASN F 316 ? CYS F 330 ASN F 335 
AC2 1 ARG F 214 ? SER F 215 ? ARG F 233 SER F 234 
AC2 2 SER F 220 ? ALA F 221 ? SER F 239 ALA F 240 
AC3 1 VAL F 344 ? ASP F 346 ? VAL F 363 ASP F 365 
AC3 2 LYS F 349 ? TYR F 354 ? LYS F 368 TYR F 373 
AC3 3 ALA F 357 ? ASP F 362 ? ALA F 376 ASP F 381 
AC3 4 GLU F 367 ? TRP F 372 ? GLU F 386 TRP F 391 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 33  ? N PHE A 52  O PHE A 56  ? O PHE A 75  
AA1 2 3 N ILE A 57  ? N ILE A 76  O ILE A 92  ? O ILE A 111 
AA1 3 4 N PHE A 93  ? N PHE A 112 O PHE A 163 ? O PHE A 182 
AA1 4 5 N MET A 164 ? N MET A 183 O VAL A 209 ? O VAL A 228 
AA1 5 6 N ILE A 213 ? N ILE A 232 O MET A 233 ? O MET A 252 
AA1 6 7 N ILE A 234 ? N ILE A 253 O VAL A 266 ? O VAL A 285 
AA1 7 8 N GLY A 269 ? N GLY A 288 O ILE A 314 ? O ILE A 333 
AA2 1 2 N LYS A 128 ? N LYS A 147 O LEU A 132 ? O LEU A 151 
AA3 1 2 N VAL A 344 ? N VAL A 363 O SER A 351 ? O SER A 370 
AA3 2 3 N TYR A 354 ? N TYR A 373 O ALA A 357 ? O ALA A 376 
AA3 3 4 N ARG A 360 ? N ARG A 379 O GLU A 369 ? O GLU A 388 
AA4 1 2 N PHE B 33  ? N PHE B 52  O CYS B 58  ? O CYS B 77  
AA4 2 3 N ILE B 57  ? N ILE B 76  O ILE B 92  ? O ILE B 111 
AA4 3 4 N PHE B 93  ? N PHE B 112 O PHE B 163 ? O PHE B 182 
AA4 4 5 N VAL B 162 ? N VAL B 181 O VAL B 209 ? O VAL B 228 
AA4 5 6 N ARG B 214 ? N ARG B 233 O ALA B 221 ? O ALA B 240 
AA5 1 2 N PHE B 33  ? N PHE B 52  O CYS B 58  ? O CYS B 77  
AA5 2 3 N ILE B 57  ? N ILE B 76  O ILE B 92  ? O ILE B 111 
AA5 3 4 N PHE B 93  ? N PHE B 112 O PHE B 163 ? O PHE B 182 
AA5 4 5 N VAL B 162 ? N VAL B 181 O VAL B 209 ? O VAL B 228 
AA5 5 6 N ILE B 213 ? N ILE B 232 O MET B 233 ? O MET B 252 
AA5 6 7 N ILE B 234 ? N ILE B 253 O VAL B 266 ? O VAL B 285 
AA5 7 8 N GLY B 269 ? N GLY B 288 O ILE B 314 ? O ILE B 333 
AA6 1 2 N ASP B 346 ? N ASP B 365 O LYS B 349 ? O LYS B 368 
AA6 2 3 N TYR B 354 ? N TYR B 373 O ALA B 357 ? O ALA B 376 
AA6 3 4 N ARG B 360 ? N ARG B 379 O GLU B 369 ? O GLU B 388 
AA7 1 2 N PHE C 33  ? N PHE C 52  O PHE C 56  ? O PHE C 75  
AA7 2 3 N ILE C 57  ? N ILE C 76  O LYS C 90  ? O LYS C 109 
AA7 3 4 N PHE C 93  ? N PHE C 112 O GLY C 161 ? O GLY C 180 
AA7 4 5 N MET C 164 ? N MET C 183 O VAL C 209 ? O VAL C 228 
AA7 5 6 N ARG C 214 ? N ARG C 233 O ALA C 221 ? O ALA C 240 
AA8 1 2 N PHE C 33  ? N PHE C 52  O PHE C 56  ? O PHE C 75  
AA8 2 3 N ILE C 57  ? N ILE C 76  O LYS C 90  ? O LYS C 109 
AA8 3 4 N PHE C 93  ? N PHE C 112 O GLY C 161 ? O GLY C 180 
AA8 4 5 N MET C 164 ? N MET C 183 O VAL C 209 ? O VAL C 228 
AA8 5 6 N TYR C 210 ? N TYR C 229 O ALA C 231 ? O ALA C 250 
AA8 6 7 N ILE C 234 ? N ILE C 253 O VAL C 266 ? O VAL C 285 
AA8 7 8 N GLY C 269 ? N GLY C 288 O ILE C 314 ? O ILE C 333 
AA9 1 2 N LYS C 128 ? N LYS C 147 O LEU C 132 ? O LEU C 151 
AB1 1 2 N VAL C 344 ? N VAL C 363 O SER C 351 ? O SER C 370 
AB1 2 3 N LEU C 350 ? N LEU C 369 O VAL C 361 ? O VAL C 380 
AB1 3 4 N ASP C 362 ? N ASP C 381 O GLU C 367 ? O GLU C 386 
AB2 1 2 N PHE D 33  ? N PHE D 52  O PHE D 56  ? O PHE D 75  
AB2 2 3 N ILE D 57  ? N ILE D 76  O LYS D 90  ? O LYS D 109 
AB2 3 4 N PHE D 93  ? N PHE D 112 O PHE D 163 ? O PHE D 182 
AB2 4 5 N MET D 164 ? N MET D 183 O VAL D 209 ? O VAL D 228 
AB2 5 6 O ILE D 208 ? O ILE D 227 N ALA D 231 ? N ALA D 250 
AB2 6 7 N ILE D 234 ? N ILE D 253 O VAL D 266 ? O VAL D 285 
AB2 7 8 N GLY D 269 ? N GLY D 288 O ILE D 314 ? O ILE D 333 
AB3 1 2 N LYS D 128 ? N LYS D 147 O LEU D 132 ? O LEU D 151 
AB4 1 2 N ARG D 214 ? N ARG D 233 O ALA D 221 ? O ALA D 240 
AB5 1 2 N VAL D 344 ? N VAL D 363 O SER D 351 ? O SER D 370 
AB5 2 3 N TYR D 354 ? N TYR D 373 O ALA D 357 ? O ALA D 376 
AB5 3 4 N ARG D 360 ? N ARG D 379 O GLU D 369 ? O GLU D 388 
AB6 1 2 N PHE E 33  ? N PHE E 52  O CYS E 58  ? O CYS E 77  
AB6 2 3 N ILE E 57  ? N ILE E 76  O LYS E 90  ? O LYS E 109 
AB6 3 4 N PHE E 93  ? N PHE E 112 O PHE E 163 ? O PHE E 182 
AB6 4 5 N MET E 164 ? N MET E 183 O VAL E 209 ? O VAL E 228 
AB6 5 6 N ARG E 214 ? N ARG E 233 O ALA E 221 ? O ALA E 240 
AB7 1 2 N PHE E 33  ? N PHE E 52  O CYS E 58  ? O CYS E 77  
AB7 2 3 N ILE E 57  ? N ILE E 76  O LYS E 90  ? O LYS E 109 
AB7 3 4 N PHE E 93  ? N PHE E 112 O PHE E 163 ? O PHE E 182 
AB7 4 5 N MET E 164 ? N MET E 183 O VAL E 209 ? O VAL E 228 
AB7 5 6 N ILE E 213 ? N ILE E 232 O MET E 233 ? O MET E 252 
AB7 6 7 N ILE E 234 ? N ILE E 253 O VAL E 266 ? O VAL E 285 
AB7 7 8 N GLY E 269 ? N GLY E 288 O ILE E 314 ? O ILE E 333 
AB8 1 2 N LYS E 128 ? N LYS E 147 O LEU E 132 ? O LEU E 151 
AB9 1 2 N VAL E 344 ? N VAL E 363 O SER E 351 ? O SER E 370 
AB9 2 3 N ARG E 352 ? N ARG E 371 O VAL E 359 ? O VAL E 378 
AB9 3 4 N SER E 358 ? N SER E 377 O ARG E 371 ? O ARG E 390 
AC1 1 2 N PHE F 33  ? N PHE F 52  O CYS F 58  ? O CYS F 77  
AC1 2 3 N ILE F 57  ? N ILE F 76  O ILE F 92  ? O ILE F 111 
AC1 3 4 N PHE F 93  ? N PHE F 112 O PHE F 163 ? O PHE F 182 
AC1 4 5 N VAL F 162 ? N VAL F 181 O VAL F 209 ? O VAL F 228 
AC1 5 6 O ILE F 208 ? O ILE F 227 N ALA F 231 ? N ALA F 250 
AC1 6 7 N ILE F 234 ? N ILE F 253 O VAL F 266 ? O VAL F 285 
AC1 7 8 N GLY F 269 ? N GLY F 288 O ILE F 314 ? O ILE F 333 
AC2 1 2 N ARG F 214 ? N ARG F 233 O ALA F 221 ? O ALA F 240 
AC3 1 2 N VAL F 344 ? N VAL F 363 O SER F 351 ? O SER F 370 
AC3 2 3 N LEU F 350 ? N LEU F 369 O VAL F 361 ? O VAL F 380 
AC3 3 4 N ARG F 360 ? N ARG F 379 O GLU F 369 ? O GLU F 388 
# 
_pdbx_entry_details.entry_id                   8RG3 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 HIS A 53  ? ? -161.86 86.90   
2  1 ALA A 185 ? ? 84.77   20.10   
3  1 PHE A 259 ? ? 53.30   -131.96 
4  1 ALA A 290 ? ? -90.29  50.51   
5  1 ASN A 335 ? ? -177.55 -172.45 
6  1 ASN A 342 ? ? -75.93  44.77   
7  1 LEU A 355 ? ? -108.43 -63.89  
8  1 LYS B 148 ? ? 56.93   5.88    
9  1 LEU B 151 ? ? 157.99  95.45   
10 1 VAL B 174 ? ? -91.32  -68.72  
11 1 ALA B 185 ? ? 87.35   19.40   
12 1 PHE B 259 ? ? 57.89   -123.01 
13 1 ALA B 290 ? ? -75.57  47.59   
14 1 ASN B 335 ? ? -172.96 -173.90 
15 1 ASN B 342 ? ? -78.45  39.72   
16 1 LEU B 355 ? ? -108.24 -63.92  
17 1 GLN C 150 ? ? 36.84   53.49   
18 1 ALA C 185 ? ? 94.21   27.48   
19 1 PHE C 259 ? ? 51.19   -130.86 
20 1 ASN C 335 ? ? -178.44 -177.68 
21 1 ASN C 342 ? ? -70.23  46.48   
22 1 LEU C 355 ? ? -108.60 -67.64  
23 1 LYS D 148 ? ? 55.58   18.69   
24 1 GLN D 150 ? ? -135.92 -44.89  
25 1 ALA D 185 ? ? 84.42   19.18   
26 1 PHE D 259 ? ? 55.00   -125.82 
27 1 PRO D 303 ? ? -47.76  152.19  
28 1 ASN D 335 ? ? -170.54 -167.34 
29 1 ASN D 342 ? ? -90.60  48.70   
30 1 ASP D 365 ? ? -150.18 84.25   
31 1 MET E 122 ? ? -79.41  22.86   
32 1 HIS E 132 ? ? -118.77 62.36   
33 1 LYS E 148 ? ? -47.80  150.03  
34 1 ALA E 185 ? ? 106.75  13.41   
35 1 PHE E 259 ? ? 56.73   -129.15 
36 1 ILE E 295 ? ? 67.11   -46.38  
37 1 ASN E 335 ? ? 176.51  -167.73 
38 1 ASN E 342 ? ? -81.84  47.43   
39 1 LEU E 355 ? ? -107.00 -66.94  
40 1 LYS F 148 ? ? 35.18   -142.01 
41 1 GLN F 150 ? ? -127.26 -84.69  
42 1 LEU F 151 ? ? -50.70  106.09  
43 1 ALA F 185 ? ? 74.45   33.24   
44 1 ALA F 245 ? ? -132.28 -30.53  
45 1 PHE F 259 ? ? 57.24   -123.27 
46 1 ASP F 296 ? ? -107.86 59.00   
47 1 ASP F 297 ? ? -18.54  -64.22  
48 1 ARG F 301 ? ? -82.14  43.50   
49 1 PRO F 303 ? ? -48.00  156.08  
50 1 ASN F 335 ? ? -172.08 -168.55 
51 1 ASN F 342 ? ? -87.29  45.94   
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    B 
_pdbx_validate_planes.auth_seq_id     269 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.196 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 20 ? A MET 1  
2   1 Y 1 A HIS 21 ? A HIS 2  
3   1 Y 1 A HIS 22 ? A HIS 3  
4   1 Y 1 A HIS 23 ? A HIS 4  
5   1 Y 1 A HIS 24 ? A HIS 5  
6   1 Y 1 A HIS 25 ? A HIS 6  
7   1 Y 1 A HIS 26 ? A HIS 7  
8   1 Y 1 A GLU 27 ? A GLU 8  
9   1 Y 1 A ASN 28 ? A ASN 9  
10  1 Y 1 A LEU 29 ? A LEU 10 
11  1 Y 1 A TYR 30 ? A TYR 11 
12  1 Y 1 A PHE 31 ? A PHE 12 
13  1 Y 1 A GLN 32 ? A GLN 13 
14  1 Y 1 A GLY 33 ? A GLY 14 
15  1 Y 1 A SER 34 ? A SER 15 
16  1 Y 1 A GLY 35 ? A GLY 16 
17  1 Y 1 A ASP 36 ? A ASP 17 
18  1 Y 1 B MET 20 ? B MET 1  
19  1 Y 1 B HIS 21 ? B HIS 2  
20  1 Y 1 B HIS 22 ? B HIS 3  
21  1 Y 1 B HIS 23 ? B HIS 4  
22  1 Y 1 B HIS 24 ? B HIS 5  
23  1 Y 1 B HIS 25 ? B HIS 6  
24  1 Y 1 B HIS 26 ? B HIS 7  
25  1 Y 1 B GLU 27 ? B GLU 8  
26  1 Y 1 B ASN 28 ? B ASN 9  
27  1 Y 1 B LEU 29 ? B LEU 10 
28  1 Y 1 B TYR 30 ? B TYR 11 
29  1 Y 1 B PHE 31 ? B PHE 12 
30  1 Y 1 B GLN 32 ? B GLN 13 
31  1 Y 1 B GLY 33 ? B GLY 14 
32  1 Y 1 B SER 34 ? B SER 15 
33  1 Y 1 B GLY 35 ? B GLY 16 
34  1 Y 1 B ASP 36 ? B ASP 17 
35  1 Y 1 B GLU 37 ? B GLU 18 
36  1 Y 1 C MET 20 ? C MET 1  
37  1 Y 1 C HIS 21 ? C HIS 2  
38  1 Y 1 C HIS 22 ? C HIS 3  
39  1 Y 1 C HIS 23 ? C HIS 4  
40  1 Y 1 C HIS 24 ? C HIS 5  
41  1 Y 1 C HIS 25 ? C HIS 6  
42  1 Y 1 C HIS 26 ? C HIS 7  
43  1 Y 1 C GLU 27 ? C GLU 8  
44  1 Y 1 C ASN 28 ? C ASN 9  
45  1 Y 1 C LEU 29 ? C LEU 10 
46  1 Y 1 C TYR 30 ? C TYR 11 
47  1 Y 1 C PHE 31 ? C PHE 12 
48  1 Y 1 C GLN 32 ? C GLN 13 
49  1 Y 1 C GLY 33 ? C GLY 14 
50  1 Y 1 C SER 34 ? C SER 15 
51  1 Y 1 C GLY 35 ? C GLY 16 
52  1 Y 1 C ASP 36 ? C ASP 17 
53  1 Y 1 D MET 20 ? D MET 1  
54  1 Y 1 D HIS 21 ? D HIS 2  
55  1 Y 1 D HIS 22 ? D HIS 3  
56  1 Y 1 D HIS 23 ? D HIS 4  
57  1 Y 1 D HIS 24 ? D HIS 5  
58  1 Y 1 D HIS 25 ? D HIS 6  
59  1 Y 1 D HIS 26 ? D HIS 7  
60  1 Y 1 D GLU 27 ? D GLU 8  
61  1 Y 1 D ASN 28 ? D ASN 9  
62  1 Y 1 D LEU 29 ? D LEU 10 
63  1 Y 1 D TYR 30 ? D TYR 11 
64  1 Y 1 D PHE 31 ? D PHE 12 
65  1 Y 1 D GLN 32 ? D GLN 13 
66  1 Y 1 D GLY 33 ? D GLY 14 
67  1 Y 1 D SER 34 ? D SER 15 
68  1 Y 1 D GLY 35 ? D GLY 16 
69  1 Y 1 D ASP 36 ? D ASP 17 
70  1 Y 1 E MET 20 ? E MET 1  
71  1 Y 1 E HIS 21 ? E HIS 2  
72  1 Y 1 E HIS 22 ? E HIS 3  
73  1 Y 1 E HIS 23 ? E HIS 4  
74  1 Y 1 E HIS 24 ? E HIS 5  
75  1 Y 1 E HIS 25 ? E HIS 6  
76  1 Y 1 E HIS 26 ? E HIS 7  
77  1 Y 1 E GLU 27 ? E GLU 8  
78  1 Y 1 E ASN 28 ? E ASN 9  
79  1 Y 1 E LEU 29 ? E LEU 10 
80  1 Y 1 E TYR 30 ? E TYR 11 
81  1 Y 1 E PHE 31 ? E PHE 12 
82  1 Y 1 E GLN 32 ? E GLN 13 
83  1 Y 1 E GLY 33 ? E GLY 14 
84  1 Y 1 E SER 34 ? E SER 15 
85  1 Y 1 E GLY 35 ? E GLY 16 
86  1 Y 1 E ASP 36 ? E ASP 17 
87  1 Y 1 E GLU 37 ? E GLU 18 
88  1 Y 1 F MET 20 ? F MET 1  
89  1 Y 1 F HIS 21 ? F HIS 2  
90  1 Y 1 F HIS 22 ? F HIS 3  
91  1 Y 1 F HIS 23 ? F HIS 4  
92  1 Y 1 F HIS 24 ? F HIS 5  
93  1 Y 1 F HIS 25 ? F HIS 6  
94  1 Y 1 F HIS 26 ? F HIS 7  
95  1 Y 1 F GLU 27 ? F GLU 8  
96  1 Y 1 F ASN 28 ? F ASN 9  
97  1 Y 1 F LEU 29 ? F LEU 10 
98  1 Y 1 F TYR 30 ? F TYR 11 
99  1 Y 1 F PHE 31 ? F PHE 12 
100 1 Y 1 F GLN 32 ? F GLN 13 
101 1 Y 1 F GLY 33 ? F GLY 14 
102 1 Y 1 F SER 34 ? F SER 15 
103 1 Y 1 F GLY 35 ? F GLY 16 
104 1 Y 1 F ASP 36 ? F ASP 17 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
EDO C1   C N N 88  
EDO O1   O N N 89  
EDO C2   C N N 90  
EDO O2   O N N 91  
EDO H11  H N N 92  
EDO H12  H N N 93  
EDO HO1  H N N 94  
EDO H21  H N N 95  
EDO H22  H N N 96  
EDO HO2  H N N 97  
GLN N    N N N 98  
GLN CA   C N S 99  
GLN C    C N N 100 
GLN O    O N N 101 
GLN CB   C N N 102 
GLN CG   C N N 103 
GLN CD   C N N 104 
GLN OE1  O N N 105 
GLN NE2  N N N 106 
GLN OXT  O N N 107 
GLN H    H N N 108 
GLN H2   H N N 109 
GLN HA   H N N 110 
GLN HB2  H N N 111 
GLN HB3  H N N 112 
GLN HG2  H N N 113 
GLN HG3  H N N 114 
GLN HE21 H N N 115 
GLN HE22 H N N 116 
GLN HXT  H N N 117 
GLU N    N N N 118 
GLU CA   C N S 119 
GLU C    C N N 120 
GLU O    O N N 121 
GLU CB   C N N 122 
GLU CG   C N N 123 
GLU CD   C N N 124 
GLU OE1  O N N 125 
GLU OE2  O N N 126 
GLU OXT  O N N 127 
GLU H    H N N 128 
GLU H2   H N N 129 
GLU HA   H N N 130 
GLU HB2  H N N 131 
GLU HB3  H N N 132 
GLU HG2  H N N 133 
GLU HG3  H N N 134 
GLU HE2  H N N 135 
GLU HXT  H N N 136 
GLY N    N N N 137 
GLY CA   C N N 138 
GLY C    C N N 139 
GLY O    O N N 140 
GLY OXT  O N N 141 
GLY H    H N N 142 
GLY H2   H N N 143 
GLY HA2  H N N 144 
GLY HA3  H N N 145 
GLY HXT  H N N 146 
HIS N    N N N 147 
HIS CA   C N S 148 
HIS C    C N N 149 
HIS O    O N N 150 
HIS CB   C N N 151 
HIS CG   C Y N 152 
HIS ND1  N Y N 153 
HIS CD2  C Y N 154 
HIS CE1  C Y N 155 
HIS NE2  N Y N 156 
HIS OXT  O N N 157 
HIS H    H N N 158 
HIS H2   H N N 159 
HIS HA   H N N 160 
HIS HB2  H N N 161 
HIS HB3  H N N 162 
HIS HD1  H N N 163 
HIS HD2  H N N 164 
HIS HE1  H N N 165 
HIS HE2  H N N 166 
HIS HXT  H N N 167 
HOH O    O N N 168 
HOH H1   H N N 169 
HOH H2   H N N 170 
ILE N    N N N 171 
ILE CA   C N S 172 
ILE C    C N N 173 
ILE O    O N N 174 
ILE CB   C N S 175 
ILE CG1  C N N 176 
ILE CG2  C N N 177 
ILE CD1  C N N 178 
ILE OXT  O N N 179 
ILE H    H N N 180 
ILE H2   H N N 181 
ILE HA   H N N 182 
ILE HB   H N N 183 
ILE HG12 H N N 184 
ILE HG13 H N N 185 
ILE HG21 H N N 186 
ILE HG22 H N N 187 
ILE HG23 H N N 188 
ILE HD11 H N N 189 
ILE HD12 H N N 190 
ILE HD13 H N N 191 
ILE HXT  H N N 192 
LEU N    N N N 193 
LEU CA   C N S 194 
LEU C    C N N 195 
LEU O    O N N 196 
LEU CB   C N N 197 
LEU CG   C N N 198 
LEU CD1  C N N 199 
LEU CD2  C N N 200 
LEU OXT  O N N 201 
LEU H    H N N 202 
LEU H2   H N N 203 
LEU HA   H N N 204 
LEU HB2  H N N 205 
LEU HB3  H N N 206 
LEU HG   H N N 207 
LEU HD11 H N N 208 
LEU HD12 H N N 209 
LEU HD13 H N N 210 
LEU HD21 H N N 211 
LEU HD22 H N N 212 
LEU HD23 H N N 213 
LEU HXT  H N N 214 
LYS N    N N N 215 
LYS CA   C N S 216 
LYS C    C N N 217 
LYS O    O N N 218 
LYS CB   C N N 219 
LYS CG   C N N 220 
LYS CD   C N N 221 
LYS CE   C N N 222 
LYS NZ   N N N 223 
LYS OXT  O N N 224 
LYS H    H N N 225 
LYS H2   H N N 226 
LYS HA   H N N 227 
LYS HB2  H N N 228 
LYS HB3  H N N 229 
LYS HG2  H N N 230 
LYS HG3  H N N 231 
LYS HD2  H N N 232 
LYS HD3  H N N 233 
LYS HE2  H N N 234 
LYS HE3  H N N 235 
LYS HZ1  H N N 236 
LYS HZ2  H N N 237 
LYS HZ3  H N N 238 
LYS HXT  H N N 239 
MET N    N N N 240 
MET CA   C N S 241 
MET C    C N N 242 
MET O    O N N 243 
MET CB   C N N 244 
MET CG   C N N 245 
MET SD   S N N 246 
MET CE   C N N 247 
MET OXT  O N N 248 
MET H    H N N 249 
MET H2   H N N 250 
MET HA   H N N 251 
MET HB2  H N N 252 
MET HB3  H N N 253 
MET HG2  H N N 254 
MET HG3  H N N 255 
MET HE1  H N N 256 
MET HE2  H N N 257 
MET HE3  H N N 258 
MET HXT  H N N 259 
PHE N    N N N 260 
PHE CA   C N S 261 
PHE C    C N N 262 
PHE O    O N N 263 
PHE CB   C N N 264 
PHE CG   C Y N 265 
PHE CD1  C Y N 266 
PHE CD2  C Y N 267 
PHE CE1  C Y N 268 
PHE CE2  C Y N 269 
PHE CZ   C Y N 270 
PHE OXT  O N N 271 
PHE H    H N N 272 
PHE H2   H N N 273 
PHE HA   H N N 274 
PHE HB2  H N N 275 
PHE HB3  H N N 276 
PHE HD1  H N N 277 
PHE HD2  H N N 278 
PHE HE1  H N N 279 
PHE HE2  H N N 280 
PHE HZ   H N N 281 
PHE HXT  H N N 282 
PRO N    N N N 283 
PRO CA   C N S 284 
PRO C    C N N 285 
PRO O    O N N 286 
PRO CB   C N N 287 
PRO CG   C N N 288 
PRO CD   C N N 289 
PRO OXT  O N N 290 
PRO H    H N N 291 
PRO HA   H N N 292 
PRO HB2  H N N 293 
PRO HB3  H N N 294 
PRO HG2  H N N 295 
PRO HG3  H N N 296 
PRO HD2  H N N 297 
PRO HD3  H N N 298 
PRO HXT  H N N 299 
SER N    N N N 300 
SER CA   C N S 301 
SER C    C N N 302 
SER O    O N N 303 
SER CB   C N N 304 
SER OG   O N N 305 
SER OXT  O N N 306 
SER H    H N N 307 
SER H2   H N N 308 
SER HA   H N N 309 
SER HB2  H N N 310 
SER HB3  H N N 311 
SER HG   H N N 312 
SER HXT  H N N 313 
THR N    N N N 314 
THR CA   C N S 315 
THR C    C N N 316 
THR O    O N N 317 
THR CB   C N R 318 
THR OG1  O N N 319 
THR CG2  C N N 320 
THR OXT  O N N 321 
THR H    H N N 322 
THR H2   H N N 323 
THR HA   H N N 324 
THR HB   H N N 325 
THR HG1  H N N 326 
THR HG21 H N N 327 
THR HG22 H N N 328 
THR HG23 H N N 329 
THR HXT  H N N 330 
TRP N    N N N 331 
TRP CA   C N S 332 
TRP C    C N N 333 
TRP O    O N N 334 
TRP CB   C N N 335 
TRP CG   C Y N 336 
TRP CD1  C Y N 337 
TRP CD2  C Y N 338 
TRP NE1  N Y N 339 
TRP CE2  C Y N 340 
TRP CE3  C Y N 341 
TRP CZ2  C Y N 342 
TRP CZ3  C Y N 343 
TRP CH2  C Y N 344 
TRP OXT  O N N 345 
TRP H    H N N 346 
TRP H2   H N N 347 
TRP HA   H N N 348 
TRP HB2  H N N 349 
TRP HB3  H N N 350 
TRP HD1  H N N 351 
TRP HE1  H N N 352 
TRP HE3  H N N 353 
TRP HZ2  H N N 354 
TRP HZ3  H N N 355 
TRP HH2  H N N 356 
TRP HXT  H N N 357 
TYR N    N N N 358 
TYR CA   C N S 359 
TYR C    C N N 360 
TYR O    O N N 361 
TYR CB   C N N 362 
TYR CG   C Y N 363 
TYR CD1  C Y N 364 
TYR CD2  C Y N 365 
TYR CE1  C Y N 366 
TYR CE2  C Y N 367 
TYR CZ   C Y N 368 
TYR OH   O N N 369 
TYR OXT  O N N 370 
TYR H    H N N 371 
TYR H2   H N N 372 
TYR HA   H N N 373 
TYR HB2  H N N 374 
TYR HB3  H N N 375 
TYR HD1  H N N 376 
TYR HD2  H N N 377 
TYR HE1  H N N 378 
TYR HE2  H N N 379 
TYR HH   H N N 380 
TYR HXT  H N N 381 
VAL N    N N N 382 
VAL CA   C N S 383 
VAL C    C N N 384 
VAL O    O N N 385 
VAL CB   C N N 386 
VAL CG1  C N N 387 
VAL CG2  C N N 388 
VAL OXT  O N N 389 
VAL H    H N N 390 
VAL H2   H N N 391 
VAL HA   H N N 392 
VAL HB   H N N 393 
VAL HG11 H N N 394 
VAL HG12 H N N 395 
VAL HG13 H N N 396 
VAL HG21 H N N 397 
VAL HG22 H N N 398 
VAL HG23 H N N 399 
VAL HXT  H N N 400 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EDO C1  O1   sing N N 83  
EDO C1  C2   sing N N 84  
EDO C1  H11  sing N N 85  
EDO C1  H12  sing N N 86  
EDO O1  HO1  sing N N 87  
EDO C2  O2   sing N N 88  
EDO C2  H21  sing N N 89  
EDO C2  H22  sing N N 90  
EDO O2  HO2  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
HIS N   CA   sing N N 138 
HIS N   H    sing N N 139 
HIS N   H2   sing N N 140 
HIS CA  C    sing N N 141 
HIS CA  CB   sing N N 142 
HIS CA  HA   sing N N 143 
HIS C   O    doub N N 144 
HIS C   OXT  sing N N 145 
HIS CB  CG   sing N N 146 
HIS CB  HB2  sing N N 147 
HIS CB  HB3  sing N N 148 
HIS CG  ND1  sing Y N 149 
HIS CG  CD2  doub Y N 150 
HIS ND1 CE1  doub Y N 151 
HIS ND1 HD1  sing N N 152 
HIS CD2 NE2  sing Y N 153 
HIS CD2 HD2  sing N N 154 
HIS CE1 NE2  sing Y N 155 
HIS CE1 HE1  sing N N 156 
HIS NE2 HE2  sing N N 157 
HIS OXT HXT  sing N N 158 
HOH O   H1   sing N N 159 
HOH O   H2   sing N N 160 
ILE N   CA   sing N N 161 
ILE N   H    sing N N 162 
ILE N   H2   sing N N 163 
ILE CA  C    sing N N 164 
ILE CA  CB   sing N N 165 
ILE CA  HA   sing N N 166 
ILE C   O    doub N N 167 
ILE C   OXT  sing N N 168 
ILE CB  CG1  sing N N 169 
ILE CB  CG2  sing N N 170 
ILE CB  HB   sing N N 171 
ILE CG1 CD1  sing N N 172 
ILE CG1 HG12 sing N N 173 
ILE CG1 HG13 sing N N 174 
ILE CG2 HG21 sing N N 175 
ILE CG2 HG22 sing N N 176 
ILE CG2 HG23 sing N N 177 
ILE CD1 HD11 sing N N 178 
ILE CD1 HD12 sing N N 179 
ILE CD1 HD13 sing N N 180 
ILE OXT HXT  sing N N 181 
LEU N   CA   sing N N 182 
LEU N   H    sing N N 183 
LEU N   H2   sing N N 184 
LEU CA  C    sing N N 185 
LEU CA  CB   sing N N 186 
LEU CA  HA   sing N N 187 
LEU C   O    doub N N 188 
LEU C   OXT  sing N N 189 
LEU CB  CG   sing N N 190 
LEU CB  HB2  sing N N 191 
LEU CB  HB3  sing N N 192 
LEU CG  CD1  sing N N 193 
LEU CG  CD2  sing N N 194 
LEU CG  HG   sing N N 195 
LEU CD1 HD11 sing N N 196 
LEU CD1 HD12 sing N N 197 
LEU CD1 HD13 sing N N 198 
LEU CD2 HD21 sing N N 199 
LEU CD2 HD22 sing N N 200 
LEU CD2 HD23 sing N N 201 
LEU OXT HXT  sing N N 202 
LYS N   CA   sing N N 203 
LYS N   H    sing N N 204 
LYS N   H2   sing N N 205 
LYS CA  C    sing N N 206 
LYS CA  CB   sing N N 207 
LYS CA  HA   sing N N 208 
LYS C   O    doub N N 209 
LYS C   OXT  sing N N 210 
LYS CB  CG   sing N N 211 
LYS CB  HB2  sing N N 212 
LYS CB  HB3  sing N N 213 
LYS CG  CD   sing N N 214 
LYS CG  HG2  sing N N 215 
LYS CG  HG3  sing N N 216 
LYS CD  CE   sing N N 217 
LYS CD  HD2  sing N N 218 
LYS CD  HD3  sing N N 219 
LYS CE  NZ   sing N N 220 
LYS CE  HE2  sing N N 221 
LYS CE  HE3  sing N N 222 
LYS NZ  HZ1  sing N N 223 
LYS NZ  HZ2  sing N N 224 
LYS NZ  HZ3  sing N N 225 
LYS OXT HXT  sing N N 226 
MET N   CA   sing N N 227 
MET N   H    sing N N 228 
MET N   H2   sing N N 229 
MET CA  C    sing N N 230 
MET CA  CB   sing N N 231 
MET CA  HA   sing N N 232 
MET C   O    doub N N 233 
MET C   OXT  sing N N 234 
MET CB  CG   sing N N 235 
MET CB  HB2  sing N N 236 
MET CB  HB3  sing N N 237 
MET CG  SD   sing N N 238 
MET CG  HG2  sing N N 239 
MET CG  HG3  sing N N 240 
MET SD  CE   sing N N 241 
MET CE  HE1  sing N N 242 
MET CE  HE2  sing N N 243 
MET CE  HE3  sing N N 244 
MET OXT HXT  sing N N 245 
PHE N   CA   sing N N 246 
PHE N   H    sing N N 247 
PHE N   H2   sing N N 248 
PHE CA  C    sing N N 249 
PHE CA  CB   sing N N 250 
PHE CA  HA   sing N N 251 
PHE C   O    doub N N 252 
PHE C   OXT  sing N N 253 
PHE CB  CG   sing N N 254 
PHE CB  HB2  sing N N 255 
PHE CB  HB3  sing N N 256 
PHE CG  CD1  doub Y N 257 
PHE CG  CD2  sing Y N 258 
PHE CD1 CE1  sing Y N 259 
PHE CD1 HD1  sing N N 260 
PHE CD2 CE2  doub Y N 261 
PHE CD2 HD2  sing N N 262 
PHE CE1 CZ   doub Y N 263 
PHE CE1 HE1  sing N N 264 
PHE CE2 CZ   sing Y N 265 
PHE CE2 HE2  sing N N 266 
PHE CZ  HZ   sing N N 267 
PHE OXT HXT  sing N N 268 
PRO N   CA   sing N N 269 
PRO N   CD   sing N N 270 
PRO N   H    sing N N 271 
PRO CA  C    sing N N 272 
PRO CA  CB   sing N N 273 
PRO CA  HA   sing N N 274 
PRO C   O    doub N N 275 
PRO C   OXT  sing N N 276 
PRO CB  CG   sing N N 277 
PRO CB  HB2  sing N N 278 
PRO CB  HB3  sing N N 279 
PRO CG  CD   sing N N 280 
PRO CG  HG2  sing N N 281 
PRO CG  HG3  sing N N 282 
PRO CD  HD2  sing N N 283 
PRO CD  HD3  sing N N 284 
PRO OXT HXT  sing N N 285 
SER N   CA   sing N N 286 
SER N   H    sing N N 287 
SER N   H2   sing N N 288 
SER CA  C    sing N N 289 
SER CA  CB   sing N N 290 
SER CA  HA   sing N N 291 
SER C   O    doub N N 292 
SER C   OXT  sing N N 293 
SER CB  OG   sing N N 294 
SER CB  HB2  sing N N 295 
SER CB  HB3  sing N N 296 
SER OG  HG   sing N N 297 
SER OXT HXT  sing N N 298 
THR N   CA   sing N N 299 
THR N   H    sing N N 300 
THR N   H2   sing N N 301 
THR CA  C    sing N N 302 
THR CA  CB   sing N N 303 
THR CA  HA   sing N N 304 
THR C   O    doub N N 305 
THR C   OXT  sing N N 306 
THR CB  OG1  sing N N 307 
THR CB  CG2  sing N N 308 
THR CB  HB   sing N N 309 
THR OG1 HG1  sing N N 310 
THR CG2 HG21 sing N N 311 
THR CG2 HG22 sing N N 312 
THR CG2 HG23 sing N N 313 
THR OXT HXT  sing N N 314 
TRP N   CA   sing N N 315 
TRP N   H    sing N N 316 
TRP N   H2   sing N N 317 
TRP CA  C    sing N N 318 
TRP CA  CB   sing N N 319 
TRP CA  HA   sing N N 320 
TRP C   O    doub N N 321 
TRP C   OXT  sing N N 322 
TRP CB  CG   sing N N 323 
TRP CB  HB2  sing N N 324 
TRP CB  HB3  sing N N 325 
TRP CG  CD1  doub Y N 326 
TRP CG  CD2  sing Y N 327 
TRP CD1 NE1  sing Y N 328 
TRP CD1 HD1  sing N N 329 
TRP CD2 CE2  doub Y N 330 
TRP CD2 CE3  sing Y N 331 
TRP NE1 CE2  sing Y N 332 
TRP NE1 HE1  sing N N 333 
TRP CE2 CZ2  sing Y N 334 
TRP CE3 CZ3  doub Y N 335 
TRP CE3 HE3  sing N N 336 
TRP CZ2 CH2  doub Y N 337 
TRP CZ2 HZ2  sing N N 338 
TRP CZ3 CH2  sing Y N 339 
TRP CZ3 HZ3  sing N N 340 
TRP CH2 HH2  sing N N 341 
TRP OXT HXT  sing N N 342 
TYR N   CA   sing N N 343 
TYR N   H    sing N N 344 
TYR N   H2   sing N N 345 
TYR CA  C    sing N N 346 
TYR CA  CB   sing N N 347 
TYR CA  HA   sing N N 348 
TYR C   O    doub N N 349 
TYR C   OXT  sing N N 350 
TYR CB  CG   sing N N 351 
TYR CB  HB2  sing N N 352 
TYR CB  HB3  sing N N 353 
TYR CG  CD1  doub Y N 354 
TYR CG  CD2  sing Y N 355 
TYR CD1 CE1  sing Y N 356 
TYR CD1 HD1  sing N N 357 
TYR CD2 CE2  doub Y N 358 
TYR CD2 HD2  sing N N 359 
TYR CE1 CZ   doub Y N 360 
TYR CE1 HE1  sing N N 361 
TYR CE2 CZ   sing Y N 362 
TYR CE2 HE2  sing N N 363 
TYR CZ  OH   sing N N 364 
TYR OH  HH   sing N N 365 
TYR OXT HXT  sing N N 366 
VAL N   CA   sing N N 367 
VAL N   H    sing N N 368 
VAL N   H2   sing N N 369 
VAL CA  C    sing N N 370 
VAL CA  CB   sing N N 371 
VAL CA  HA   sing N N 372 
VAL C   O    doub N N 373 
VAL C   OXT  sing N N 374 
VAL CB  CG1  sing N N 375 
VAL CB  CG2  sing N N 376 
VAL CB  HB   sing N N 377 
VAL CG1 HG11 sing N N 378 
VAL CG1 HG12 sing N N 379 
VAL CG1 HG13 sing N N 380 
VAL CG2 HG21 sing N N 381 
VAL CG2 HG22 sing N N 382 
VAL CG2 HG23 sing N N 383 
VAL OXT HXT  sing N N 384 
# 
_pdbx_audit_support.funding_organization   'Other government' 
_pdbx_audit_support.country                Spain 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8RG3 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010888 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.001047 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012210 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006267 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . GLU A 1 18  ? 1.221   -20.755 62.736  1.00 42.57  ? 37  GLU A N   1 
ATOM   2     C CA  . GLU A 1 18  ? -0.101  -21.228 62.347  1.00 43.16  ? 37  GLU A CA  1 
ATOM   3     C C   . GLU A 1 18  ? -1.045  -21.384 63.577  1.00 40.27  ? 37  GLU A C   1 
ATOM   4     O O   . GLU A 1 18  ? -1.602  -20.393 64.088  1.00 37.72  ? 37  GLU A O   1 
ATOM   5     C CB  . GLU A 1 18  ? 0.033   -22.566 61.578  1.00 46.32  ? 37  GLU A CB  1 
ATOM   6     N N   . SER A 1 19  ? -1.215  -22.631 64.053  1.00 45.08  ? 38  SER A N   1 
ATOM   7     C CA  . SER A 1 19  ? -2.277  -22.989 65.003  1.00 43.56  ? 38  SER A CA  1 
ATOM   8     C C   . SER A 1 19  ? -2.085  -22.423 66.407  1.00 40.82  ? 38  SER A C   1 
ATOM   9     O O   . SER A 1 19  ? -3.056  -22.354 67.177  1.00 40.96  ? 38  SER A O   1 
ATOM   10    C CB  . SER A 1 19  ? -2.365  -24.512 65.114  1.00 45.37  ? 38  SER A CB  1 
ATOM   11    O OG  . SER A 1 19  ? -1.231  -24.981 65.849  1.00 45.06  ? 38  SER A OG  1 
ATOM   12    N N   . HIS A 1 20  ? -0.870  -22.032 66.782  1.00 37.40  ? 39  HIS A N   1 
ATOM   13    C CA  . HIS A 1 20  ? -0.663  -21.381 68.060  1.00 35.82  ? 39  HIS A CA  1 
ATOM   14    C C   . HIS A 1 20  ? -0.766  -19.861 67.971  1.00 34.57  ? 39  HIS A C   1 
ATOM   15    O O   . HIS A 1 20  ? -0.564  -19.189 68.990  1.00 33.91  ? 39  HIS A O   1 
ATOM   16    C CB  . HIS A 1 20  ? 0.688   -21.785 68.644  1.00 35.53  ? 39  HIS A CB  1 
ATOM   17    C CG  . HIS A 1 20  ? 1.891   -21.375 67.837  1.00 35.57  ? 39  HIS A CG  1 
ATOM   18    N ND1 . HIS A 1 20  ? 1.976   -21.515 66.464  1.00 36.97  ? 39  HIS A ND1 1 
ATOM   19    C CD2 . HIS A 1 20  ? 3.107   -20.931 68.242  1.00 35.28  ? 39  HIS A CD2 1 
ATOM   20    C CE1 . HIS A 1 20  ? 3.174   -21.121 66.057  1.00 37.15  ? 39  HIS A CE1 1 
ATOM   21    N NE2 . HIS A 1 20  ? 3.884   -20.785 67.118  1.00 35.53  ? 39  HIS A NE2 1 
ATOM   22    N N   . TYR A 1 21  ? -1.091  -19.344 66.790  1.00 32.63  ? 40  TYR A N   1 
ATOM   23    C CA  . TYR A 1 21  ? -1.302  -17.919 66.599  1.00 32.31  ? 40  TYR A CA  1 
ATOM   24    C C   . TYR A 1 21  ? -2.629  -17.517 67.231  1.00 32.55  ? 40  TYR A C   1 
ATOM   25    O O   . TYR A 1 21  ? -3.567  -18.314 67.290  1.00 33.22  ? 40  TYR A O   1 
ATOM   26    C CB  . TYR A 1 21  ? -1.327  -17.577 65.111  1.00 32.89  ? 40  TYR A CB  1 
ATOM   27    C CG  . TYR A 1 21  ? 0.031   -17.495 64.491  1.00 32.58  ? 40  TYR A CG  1 
ATOM   28    C CD1 . TYR A 1 21  ? 1.142   -17.887 65.201  1.00 31.90  ? 40  TYR A CD1 1 
ATOM   29    C CD2 . TYR A 1 21  ? 0.206   -16.998 63.217  1.00 33.07  ? 40  TYR A CD2 1 
ATOM   30    C CE1 . TYR A 1 21  ? 2.386   -17.804 64.669  1.00 32.00  ? 40  TYR A CE1 1 
ATOM   31    C CE2 . TYR A 1 21  ? 1.453   -16.897 62.664  1.00 33.54  ? 40  TYR A CE2 1 
ATOM   32    C CZ  . TYR A 1 21  ? 2.544   -17.302 63.401  1.00 33.00  ? 40  TYR A CZ  1 
ATOM   33    O OH  . TYR A 1 21  ? 3.831   -17.227 62.924  1.00 33.53  ? 40  TYR A OH  1 
ATOM   34    N N   . PRO A 1 22  ? -2.727  -16.296 67.726  1.00 30.20  ? 41  PRO A N   1 
ATOM   35    C CA  . PRO A 1 22  ? -4.041  -15.755 68.100  1.00 31.07  ? 41  PRO A CA  1 
ATOM   36    C C   . PRO A 1 22  ? -5.006  -15.832 66.925  1.00 31.92  ? 41  PRO A C   1 
ATOM   37    O O   . PRO A 1 22  ? -4.605  -15.706 65.779  1.00 32.01  ? 41  PRO A O   1 
ATOM   38    C CB  . PRO A 1 22  ? -3.739  -14.296 68.472  1.00 30.74  ? 41  PRO A CB  1 
ATOM   39    C CG  . PRO A 1 22  ? -2.248  -14.220 68.643  1.00 29.85  ? 41  PRO A CG  1 
ATOM   40    C CD  . PRO A 1 22  ? -1.653  -15.284 67.771  1.00 29.51  ? 41  PRO A CD  1 
ATOM   41    N N   . GLU A 1 23  ? -6.289  -16.007 67.221  1.00 31.81  ? 42  GLU A N   1 
ATOM   42    C CA  . GLU A 1 23  ? -7.319  -15.998 66.191  1.00 32.65  ? 42  GLU A CA  1 
ATOM   43    C C   . GLU A 1 23  ? -7.411  -14.586 65.610  1.00 33.03  ? 42  GLU A C   1 
ATOM   44    O O   . GLU A 1 23  ? -7.639  -13.616 66.340  1.00 33.53  ? 42  GLU A O   1 
ATOM   45    C CB  . GLU A 1 23  ? -8.655  -16.460 66.761  1.00 33.99  ? 42  GLU A CB  1 
ATOM   46    N N   . PHE A 1 24  ? -7.196  -14.479 64.307  1.00 33.22  ? 43  PHE A N   1 
ATOM   47    C CA  . PHE A 1 24  ? -7.114  -13.228 63.587  1.00 33.27  ? 43  PHE A CA  1 
ATOM   48    C C   . PHE A 1 24  ? -8.337  -13.044 62.714  1.00 34.52  ? 43  PHE A C   1 
ATOM   49    O O   . PHE A 1 24  ? -8.810  -13.991 62.084  1.00 35.21  ? 43  PHE A O   1 
ATOM   50    C CB  . PHE A 1 24  ? -5.886  -13.177 62.682  1.00 32.78  ? 43  PHE A CB  1 
ATOM   51    C CG  . PHE A 1 24  ? -5.771  -11.908 61.864  1.00 32.78  ? 43  PHE A CG  1 
ATOM   52    C CD1 . PHE A 1 24  ? -5.189  -10.768 62.402  1.00 32.44  ? 43  PHE A CD1 1 
ATOM   53    C CD2 . PHE A 1 24  ? -6.231  -11.844 60.581  1.00 34.02  ? 43  PHE A CD2 1 
ATOM   54    C CE1 . PHE A 1 24  ? -5.081  -9.594  61.663  1.00 33.13  ? 43  PHE A CE1 1 
ATOM   55    C CE2 . PHE A 1 24  ? -6.087  -10.672 59.842  1.00 34.35  ? 43  PHE A CE2 1 
ATOM   56    C CZ  . PHE A 1 24  ? -5.516  -9.566  60.388  1.00 34.02  ? 43  PHE A CZ  1 
ATOM   57    N N   . SER A 1 25  ? -8.818  -11.813 62.656  1.00 34.02  ? 44  SER A N   1 
ATOM   58    C CA  . SER A 1 25  ? -9.986  -11.445 61.898  1.00 35.27  ? 44  SER A CA  1 
ATOM   59    C C   . SER A 1 25  ? -9.802  -10.062 61.295  1.00 35.40  ? 44  SER A C   1 
ATOM   60    O O   . SER A 1 25  ? -9.101  -9.182  61.837  1.00 35.17  ? 44  SER A O   1 
ATOM   61    C CB  . SER A 1 25  ? -11.248 -11.395 62.753  1.00 36.54  ? 44  SER A CB  1 
ATOM   62    O OG  . SER A 1 25  ? -12.360 -10.984 61.961  1.00 37.54  ? 44  SER A OG  1 
ATOM   63    N N   . TRP A 1 26  ? -10.503 -9.862  60.202  1.00 36.63  ? 45  TRP A N   1 
ATOM   64    C CA  . TRP A 1 26  ? -10.547 -8.604  59.510  1.00 37.20  ? 45  TRP A CA  1 
ATOM   65    C C   . TRP A 1 26  ? -11.860 -7.886  59.737  1.00 37.75  ? 45  TRP A C   1 
ATOM   66    O O   . TRP A 1 26  ? -12.084 -6.830  59.140  1.00 38.68  ? 45  TRP A O   1 
ATOM   67    C CB  . TRP A 1 26  ? -10.377 -8.860  58.027  1.00 37.60  ? 45  TRP A CB  1 
ATOM   68    C CG  . TRP A 1 26  ? -8.995  -9.155  57.527  1.00 37.20  ? 45  TRP A CG  1 
ATOM   69    C CD1 . TRP A 1 26  ? -8.582  -10.291 56.905  1.00 38.16  ? 45  TRP A CD1 1 
ATOM   70    C CD2 . TRP A 1 26  ? -7.857  -8.259  57.533  1.00 36.49  ? 45  TRP A CD2 1 
ATOM   71    N NE1 . TRP A 1 26  ? -7.274  -10.175 56.530  1.00 38.05  ? 45  TRP A NE1 1 
ATOM   72    C CE2 . TRP A 1 26  ? -6.796  -8.939  56.908  1.00 37.03  ? 45  TRP A CE2 1 
ATOM   73    C CE3 . TRP A 1 26  ? -7.645  -6.956  57.988  1.00 36.63  ? 45  TRP A CE3 1 
ATOM   74    C CZ2 . TRP A 1 26  ? -5.526  -8.365  56.751  1.00 36.66  ? 45  TRP A CZ2 1 
ATOM   75    C CZ3 . TRP A 1 26  ? -6.380  -6.385  57.827  1.00 36.40  ? 45  TRP A CZ3 1 
ATOM   76    C CH2 . TRP A 1 26  ? -5.346  -7.084  57.207  1.00 36.51  ? 45  TRP A CH2 1 
ATOM   77    N N   . ASP A 1 27  ? -12.752 -8.433  60.554  1.00 37.06  ? 46  ASP A N   1 
ATOM   78    C CA  . ASP A 1 27  ? -14.042 -7.789  60.667  1.00 37.61  ? 46  ASP A CA  1 
ATOM   79    C C   . ASP A 1 27  ? -13.904 -6.300  61.029  1.00 37.96  ? 46  ASP A C   1 
ATOM   80    O O   . ASP A 1 27  ? -14.556 -5.431  60.440  1.00 38.56  ? 46  ASP A O   1 
ATOM   81    C CB  . ASP A 1 27  ? -14.879 -8.509  61.684  1.00 37.41  ? 46  ASP A CB  1 
ATOM   82    C CG  . ASP A 1 27  ? -16.262 -7.935  61.754  1.00 37.56  ? 46  ASP A CG  1 
ATOM   83    O OD1 . ASP A 1 27  ? -16.364 -6.720  62.067  1.00 37.62  ? 46  ASP A OD1 1 
ATOM   84    O OD2 . ASP A 1 27  ? -17.245 -8.680  61.442  1.00 38.46  ? 46  ASP A OD2 1 
ATOM   85    N N   . THR A 1 28  ? -13.055 -5.982  61.998  1.00 35.57  ? 47  THR A N   1 
ATOM   86    C CA  . THR A 1 28  ? -12.665 -4.613  62.284  1.00 35.66  ? 47  THR A CA  1 
ATOM   87    C C   . THR A 1 28  ? -11.155 -4.514  62.349  1.00 34.89  ? 47  THR A C   1 
ATOM   88    O O   . THR A 1 28  ? -10.434 -5.472  62.084  1.00 34.32  ? 47  THR A O   1 
ATOM   89    C CB  . THR A 1 28  ? -13.279 -4.122  63.588  1.00 35.92  ? 47  THR A CB  1 
ATOM   90    O OG1 . THR A 1 28  ? -12.833 -4.950  64.637  1.00 35.53  ? 47  THR A OG1 1 
ATOM   91    C CG2 . THR A 1 28  ? -14.788 -4.158  63.465  1.00 36.63  ? 47  THR A CG2 1 
ATOM   92    N N   . VAL A 1 29  ? -10.691 -3.311  62.643  1.00 32.88  ? 48  VAL A N   1 
ATOM   93    C CA  . VAL A 1 29  ? -9.245  -3.159  62.769  1.00 32.32  ? 48  VAL A CA  1 
ATOM   94    C C   . VAL A 1 29  ? -8.729  -4.110  63.822  1.00 31.40  ? 48  VAL A C   1 
ATOM   95    O O   . VAL A 1 29  ? -9.374  -4.223  64.903  1.00 31.29  ? 48  VAL A O   1 
ATOM   96    C CB  . VAL A 1 29  ? -8.882  -1.708  63.131  1.00 32.54  ? 48  VAL A CB  1 
ATOM   97    C CG1 . VAL A 1 29  ? -7.340  -1.608  63.404  1.00 31.80  ? 48  VAL A CG1 1 
ATOM   98    C CG2 . VAL A 1 29  ? -9.310  -0.786  62.034  1.00 33.46  ? 48  VAL A CG2 1 
ATOM   99    N N   . PRO A 1 30  ? -7.686  -4.849  63.541  1.00 31.61  ? 49  PRO A N   1 
ATOM   100   C CA  . PRO A 1 30  ? -7.177  -5.836  64.461  1.00 30.76  ? 49  PRO A CA  1 
ATOM   101   C C   . PRO A 1 30  ? -6.277  -5.187  65.497  1.00 30.59  ? 49  PRO A C   1 
ATOM   102   O O   . PRO A 1 30  ? -5.229  -4.616  65.165  1.00 30.30  ? 49  PRO A O   1 
ATOM   103   C CB  . PRO A 1 30  ? -6.438  -6.829  63.556  1.00 30.52  ? 49  PRO A CB  1 
ATOM   104   C CG  . PRO A 1 30  ? -6.161  -6.132  62.349  1.00 31.55  ? 49  PRO A CG  1 
ATOM   105   C CD  . PRO A 1 30  ? -7.074  -4.980  62.208  1.00 31.91  ? 49  PRO A CD  1 
ATOM   106   N N   . ILE A 1 31  ? -6.696  -5.363  66.750  1.00 29.68  ? 50  ILE A N   1 
ATOM   107   C CA  . ILE A 1 31  ? -6.152  -4.662  67.902  1.00 29.76  ? 50  ILE A CA  1 
ATOM   108   C C   . ILE A 1 31  ? -5.460  -5.638  68.831  1.00 28.17  ? 50  ILE A C   1 
ATOM   109   O O   . ILE A 1 31  ? -6.006  -6.701  69.135  1.00 28.41  ? 50  ILE A O   1 
ATOM   110   C CB  . ILE A 1 31  ? -7.290  -3.936  68.656  1.00 31.54  ? 50  ILE A CB  1 
ATOM   111   C CG1 . ILE A 1 31  ? -7.929  -2.842  67.790  1.00 33.02  ? 50  ILE A CG1 1 
ATOM   112   C CG2 . ILE A 1 31  ? -6.756  -3.451  69.981  1.00 31.35  ? 50  ILE A CG2 1 
ATOM   113   C CD1 . ILE A 1 31  ? -6.999  -1.737  67.342  1.00 33.16  ? 50  ILE A CD1 1 
ATOM   114   N N   . ALA A 1 32  ? -4.273  -5.262  69.312  1.00 30.13  ? 51  ALA A N   1 
ATOM   115   C CA  . ALA A 1 32  ? -3.585  -5.958  70.388  1.00 28.84  ? 51  ALA A CA  1 
ATOM   116   C C   . ALA A 1 32  ? -3.407  -5.008  71.564  1.00 28.05  ? 51  ALA A C   1 
ATOM   117   O O   . ALA A 1 32  ? -3.522  -3.780  71.415  1.00 28.77  ? 51  ALA A O   1 
ATOM   118   C CB  . ALA A 1 32  ? -2.228  -6.474  69.900  1.00 27.61  ? 51  ALA A CB  1 
ATOM   119   N N   . PHE A 1 33  ? -3.110  -5.572  72.735  1.00 29.33  ? 52  PHE A N   1 
ATOM   120   C CA  . PHE A 1 33  ? -2.772  -4.765  73.904  1.00 28.06  ? 52  PHE A CA  1 
ATOM   121   C C   . PHE A 1 33  ? -1.374  -5.114  74.410  1.00 26.26  ? 52  PHE A C   1 
ATOM   122   O O   . PHE A 1 33  ? -0.875  -6.228  74.175  1.00 25.98  ? 52  PHE A O   1 
ATOM   123   C CB  . PHE A 1 33  ? -3.750  -4.958  75.059  1.00 28.69  ? 52  PHE A CB  1 
ATOM   124   C CG  . PHE A 1 33  ? -5.125  -4.458  74.771  1.00 30.76  ? 52  PHE A CG  1 
ATOM   125   C CD1 . PHE A 1 33  ? -5.498  -3.218  75.187  1.00 31.23  ? 52  PHE A CD1 1 
ATOM   126   C CD2 . PHE A 1 33  ? -6.056  -5.250  74.140  1.00 32.42  ? 52  PHE A CD2 1 
ATOM   127   C CE1 . PHE A 1 33  ? -6.748  -2.740  74.961  1.00 33.50  ? 52  PHE A CE1 1 
ATOM   128   C CE2 . PHE A 1 33  ? -7.315  -4.779  73.889  1.00 34.53  ? 52  PHE A CE2 1 
ATOM   129   C CZ  . PHE A 1 33  ? -7.661  -3.498  74.292  1.00 35.31  ? 52  PHE A CZ  1 
ATOM   130   N N   . HIS A 1 34  ? -0.782  -4.165  75.143  1.00 30.56  ? 53  HIS A N   1 
ATOM   131   C CA  . HIS A 1 34  ? 0.567   -4.274  75.685  1.00 29.22  ? 53  HIS A CA  1 
ATOM   132   C C   . HIS A 1 34  ? 0.710   -3.233  76.814  1.00 28.72  ? 53  HIS A C   1 
ATOM   133   O O   . HIS A 1 34  ? 1.172   -2.109  76.607  1.00 29.37  ? 53  HIS A O   1 
ATOM   134   C CB  . HIS A 1 34  ? 1.610   -4.074  74.640  1.00 29.43  ? 53  HIS A CB  1 
ATOM   135   C CG  . HIS A 1 34  ? 2.989   -4.311  75.149  1.00 28.69  ? 53  HIS A CG  1 
ATOM   136   N ND1 . HIS A 1 34  ? 3.857   -5.200  74.558  1.00 29.22  ? 53  HIS A ND1 1 
ATOM   137   C CD2 . HIS A 1 34  ? 3.622   -3.847  76.251  1.00 28.47  ? 53  HIS A CD2 1 
ATOM   138   C CE1 . HIS A 1 34  ? 4.979   -5.250  75.254  1.00 28.50  ? 53  HIS A CE1 1 
ATOM   139   N NE2 . HIS A 1 34  ? 4.869   -4.423  76.281  1.00 28.12  ? 53  HIS A NE2 1 
ATOM   140   N N   . PHE A 1 35  ? 0.318   -3.634  78.018  1.00 28.29  ? 54  PHE A N   1 
ATOM   141   C CA  . PHE A 1 35  ? 0.420   -2.723  79.140  1.00 28.20  ? 54  PHE A CA  1 
ATOM   142   C C   . PHE A 1 35  ? 0.453   -3.474  80.463  1.00 27.47  ? 54  PHE A C   1 
ATOM   143   O O   . PHE A 1 35  ? 0.247   -4.686  80.520  1.00 27.32  ? 54  PHE A O   1 
ATOM   144   C CB  . PHE A 1 35  ? -0.736  -1.742  79.086  1.00 29.08  ? 54  PHE A CB  1 
ATOM   145   C CG  . PHE A 1 35  ? -2.047  -2.345  79.414  1.00 29.44  ? 54  PHE A CG  1 
ATOM   146   C CD1 . PHE A 1 35  ? -2.457  -2.456  80.729  1.00 29.88  ? 54  PHE A CD1 1 
ATOM   147   C CD2 . PHE A 1 35  ? -2.886  -2.794  78.427  1.00 30.57  ? 54  PHE A CD2 1 
ATOM   148   C CE1 . PHE A 1 35  ? -3.689  -3.007  81.044  1.00 30.65  ? 54  PHE A CE1 1 
ATOM   149   C CE2 . PHE A 1 35  ? -4.112  -3.350  78.734  1.00 31.47  ? 54  PHE A CE2 1 
ATOM   150   C CZ  . PHE A 1 35  ? -4.528  -3.440  80.026  1.00 31.48  ? 54  PHE A CZ  1 
ATOM   151   N N   . GLY A 1 36  ? 0.732   -2.723  81.528  1.00 26.15  ? 55  GLY A N   1 
ATOM   152   C CA  . GLY A 1 36  ? 0.657   -3.238  82.882  1.00 26.05  ? 55  GLY A CA  1 
ATOM   153   C C   . GLY A 1 36  ? -0.118  -2.323  83.812  1.00 26.48  ? 55  GLY A C   1 
ATOM   154   O O   . GLY A 1 36  ? -0.104  -1.117  83.674  1.00 27.25  ? 55  GLY A O   1 
ATOM   155   N N   . LYS A 1 37  ? -0.805  -2.911  84.740  1.00 25.09  ? 56  LYS A N   1 
ATOM   156   C CA  . LYS A 1 37  ? -1.476  -2.210  85.813  1.00 25.53  ? 56  LYS A CA  1 
ATOM   157   C C   . LYS A 1 37  ? -0.789  -2.618  87.125  1.00 26.01  ? 56  LYS A C   1 
ATOM   158   O O   . LYS A 1 37  ? -1.063  -3.677  87.701  1.00 26.20  ? 56  LYS A O   1 
ATOM   159   C CB  . LYS A 1 37  ? -2.949  -2.540  85.826  1.00 25.74  ? 56  LYS A CB  1 
ATOM   160   C CG  . LYS A 1 37  ? -3.709  -1.846  86.932  1.00 26.48  ? 56  LYS A CG  1 
ATOM   161   C CD  . LYS A 1 37  ? -5.162  -2.296  86.981  1.00 27.01  ? 56  LYS A CD  1 
ATOM   162   C CE  . LYS A 1 37  ? -5.875  -1.723  88.161  1.00 27.55  ? 56  LYS A CE  1 
ATOM   163   N NZ  . LYS A 1 37  ? -7.270  -2.215  88.172  1.00 28.10  ? 56  LYS A NZ  1 
ATOM   164   N N   . SER A 1 38  ? 0.066   -1.724  87.636  1.00 28.57  ? 57  SER A N   1 
ATOM   165   C CA  . SER A 1 38  ? 0.880   -2.043  88.806  1.00 29.75  ? 57  SER A CA  1 
ATOM   166   C C   . SER A 1 38  ? 0.053   -2.154  90.070  1.00 30.10  ? 57  SER A C   1 
ATOM   167   O O   . SER A 1 38  ? 0.265   -3.067  90.871  1.00 30.54  ? 57  SER A O   1 
ATOM   168   C CB  . SER A 1 38  ? 1.946   -0.971  88.973  1.00 31.43  ? 57  SER A CB  1 
ATOM   169   O OG  . SER A 1 38  ? 3.135   -1.392  88.315  1.00 31.46  ? 57  SER A OG  1 
ATOM   170   N N   . GLN A 1 39  ? -0.897  -1.245  90.267  1.00 28.77  ? 58  GLN A N   1 
ATOM   171   C CA  . GLN A 1 39  ? -1.636  -1.209  91.526  1.00 29.99  ? 58  GLN A CA  1 
ATOM   172   C C   . GLN A 1 39  ? -2.507  -2.436  91.787  1.00 29.37  ? 58  GLN A C   1 
ATOM   173   O O   . GLN A 1 39  ? -2.973  -2.603  92.911  1.00 30.42  ? 58  GLN A O   1 
ATOM   174   C CB  . GLN A 1 39  ? -2.499  0.062   91.540  1.00 31.58  ? 58  GLN A CB  1 
ATOM   175   C CG  . GLN A 1 39  ? -3.477  0.060   90.402  1.00 32.09  ? 58  GLN A CG  1 
ATOM   176   C CD  . GLN A 1 39  ? -3.061  0.899   89.170  1.00 32.29  ? 58  GLN A CD  1 
ATOM   177   O OE1 . GLN A 1 39  ? -1.882  0.975   88.764  1.00 31.45  ? 58  GLN A OE1 1 
ATOM   178   N NE2 . GLN A 1 39  ? -4.075  1.497   88.536  1.00 33.03  ? 58  GLN A NE2 1 
ATOM   179   N N   . GLY A 1 40  ? -2.756  -3.289  90.807  1.00 29.09  ? 59  GLY A N   1 
ATOM   180   C CA  . GLY A 1 40  ? -3.680  -4.382  91.013  1.00 28.99  ? 59  GLY A CA  1 
ATOM   181   C C   . GLY A 1 40  ? -4.017  -5.069  89.701  1.00 27.92  ? 59  GLY A C   1 
ATOM   182   O O   . GLY A 1 40  ? -3.602  -4.654  88.604  1.00 27.66  ? 59  GLY A O   1 
ATOM   183   N N   . LEU A 1 41  ? -4.744  -6.172  89.837  1.00 28.71  ? 60  LEU A N   1 
ATOM   184   C CA  . LEU A 1 41  ? -5.310  -6.781  88.645  1.00 28.53  ? 60  LEU A CA  1 
ATOM   185   C C   . LEU A 1 41  ? -6.322  -5.840  88.008  1.00 28.65  ? 60  LEU A C   1 
ATOM   186   O O   . LEU A 1 41  ? -6.970  -5.028  88.685  1.00 29.18  ? 60  LEU A O   1 
ATOM   187   C CB  . LEU A 1 41  ? -6.024  -8.086  88.963  1.00 29.56  ? 60  LEU A CB  1 
ATOM   188   C CG  . LEU A 1 41  ? -5.151  -9.200  89.512  1.00 30.20  ? 60  LEU A CG  1 
ATOM   189   C CD1 . LEU A 1 41  ? -5.984  -10.351 89.977  1.00 31.60  ? 60  LEU A CD1 1 
ATOM   190   C CD2 . LEU A 1 41  ? -4.163  -9.666  88.442  1.00 30.00  ? 60  LEU A CD2 1 
ATOM   191   N N   . LEU A 1 42  ? -6.501  -6.004  86.697  1.00 27.31  ? 61  LEU A N   1 
ATOM   192   C CA  . LEU A 1 42  ? -7.663  -5.463  86.031  1.00 27.98  ? 61  LEU A CA  1 
ATOM   193   C C   . LEU A 1 42  ? -8.902  -5.717  86.870  1.00 28.78  ? 61  LEU A C   1 
ATOM   194   O O   . LEU A 1 42  ? -9.047  -6.769  87.482  1.00 29.14  ? 61  LEU A O   1 
ATOM   195   C CB  . LEU A 1 42  ? -7.816  -6.089  84.653  1.00 28.64  ? 61  LEU A CB  1 
ATOM   196   C CG  . LEU A 1 42  ? -6.606  -5.990  83.760  1.00 28.43  ? 61  LEU A CG  1 
ATOM   197   C CD1 . LEU A 1 42  ? -6.822  -6.620  82.433  1.00 29.61  ? 61  LEU A CD1 1 
ATOM   198   C CD2 . LEU A 1 42  ? -6.271  -4.546  83.516  1.00 28.55  ? 61  LEU A CD2 1 
ATOM   199   N N   . THR A 1 43  ? -9.763  -4.719  86.950  1.00 30.72  ? 62  THR A N   1 
ATOM   200   C CA  . THR A 1 43  ? -11.108 -4.964  87.419  1.00 31.40  ? 62  THR A CA  1 
ATOM   201   C C   . THR A 1 43  ? -11.840 -5.838  86.408  1.00 32.48  ? 62  THR A C   1 
ATOM   202   O O   . THR A 1 43  ? -11.463 -5.940  85.236  1.00 32.73  ? 62  THR A O   1 
ATOM   203   C CB  . THR A 1 43  ? -11.868 -3.661  87.603  1.00 32.14  ? 62  THR A CB  1 
ATOM   204   O OG1 . THR A 1 43  ? -12.140 -3.125  86.302  1.00 32.83  ? 62  THR A OG1 1 
ATOM   205   C CG2 . THR A 1 43  ? -11.060 -2.662  88.400  1.00 31.91  ? 62  THR A CG2 1 
ATOM   206   N N   . LYS A 1 44  ? -12.907 -6.467  86.876  1.00 32.97  ? 63  LYS A N   1 
ATOM   207   C CA  . LYS A 1 44  ? -13.731 -7.252  85.972  1.00 34.92  ? 63  LYS A CA  1 
ATOM   208   C C   . LYS A 1 44  ? -14.027 -6.452  84.704  1.00 35.00  ? 63  LYS A C   1 
ATOM   209   O O   . LYS A 1 44  ? -13.832 -6.946  83.583  1.00 35.67  ? 63  LYS A O   1 
ATOM   210   C CB  . LYS A 1 44  ? -15.004 -7.703  86.702  1.00 37.22  ? 63  LYS A CB  1 
ATOM   211   C CG  . LYS A 1 44  ? -16.172 -7.994  85.804  1.00 39.54  ? 63  LYS A CG  1 
ATOM   212   C CD  . LYS A 1 44  ? -16.423 -9.440  85.568  1.00 40.88  ? 63  LYS A CD  1 
ATOM   213   C CE  . LYS A 1 44  ? -17.481 -9.557  84.432  1.00 42.24  ? 63  LYS A CE  1 
ATOM   214   N NZ  . LYS A 1 44  ? -18.900 -9.506  84.966  1.00 43.06  ? 63  LYS A NZ  1 
ATOM   215   N N   . GLU A 1 45  ? -14.475 -5.199  84.865  1.00 34.48  ? 64  GLU A N   1 
ATOM   216   C CA  . GLU A 1 45  ? -14.895 -4.401  83.713  1.00 35.50  ? 64  GLU A CA  1 
ATOM   217   C C   . GLU A 1 45  ? -13.732 -4.061  82.788  1.00 34.53  ? 64  GLU A C   1 
ATOM   218   O O   . GLU A 1 45  ? -13.887 -4.067  81.554  1.00 35.58  ? 64  GLU A O   1 
ATOM   219   C CB  . GLU A 1 45  ? -15.586 -3.163  84.226  1.00 36.35  ? 64  GLU A CB  1 
ATOM   220   C CG  . GLU A 1 45  ? -16.930 -3.476  84.905  1.00 37.53  ? 64  GLU A CG  1 
ATOM   221   C CD  . GLU A 1 45  ? -16.848 -3.895  86.404  1.00 37.95  ? 64  GLU A CD  1 
ATOM   222   O OE1 . GLU A 1 45  ? -15.732 -3.932  87.023  1.00 37.38  ? 64  GLU A OE1 1 
ATOM   223   O OE2 . GLU A 1 45  ? -17.959 -4.155  86.955  1.00 39.49  ? 64  GLU A OE2 1 
ATOM   224   N N   . GLU A 1 46  ? -12.555 -3.805  83.361  1.00 33.61  ? 65  GLU A N   1 
ATOM   225   C CA  . GLU A 1 46  ? -11.352 -3.606  82.551  1.00 33.34  ? 65  GLU A CA  1 
ATOM   226   C C   . GLU A 1 46  ? -10.948 -4.880  81.809  1.00 34.00  ? 65  GLU A C   1 
ATOM   227   O O   . GLU A 1 46  ? -10.537 -4.821  80.650  1.00 34.63  ? 65  GLU A O   1 
ATOM   228   C CB  . GLU A 1 46  ? -10.204 -3.157  83.451  1.00 31.84  ? 65  GLU A CB  1 
ATOM   229   C CG  . GLU A 1 46  ? -10.343 -1.733  83.982  1.00 32.08  ? 65  GLU A CG  1 
ATOM   230   C CD  . GLU A 1 46  ? -9.447  -1.455  85.181  1.00 31.27  ? 65  GLU A CD  1 
ATOM   231   O OE1 . GLU A 1 46  ? -8.873  -2.417  85.732  1.00 30.34  ? 65  GLU A OE1 1 
ATOM   232   O OE2 . GLU A 1 46  ? -9.316  -0.264  85.550  1.00 31.80  ? 65  GLU A OE2 1 
ATOM   233   N N   . ALA A 1 47  ? -11.009 -6.038  82.475  1.00 32.74  ? 66  ALA A N   1 
ATOM   234   C CA  . ALA A 1 47  ? -10.680 -7.289  81.797  1.00 33.31  ? 66  ALA A CA  1 
ATOM   235   C C   . ALA A 1 47  ? -11.679 -7.587  80.687  1.00 35.08  ? 66  ALA A C   1 
ATOM   236   O O   . ALA A 1 47  ? -11.294 -8.003  79.593  1.00 36.02  ? 66  ALA A O   1 
ATOM   237   C CB  . ALA A 1 47  ? -10.647 -8.437  82.793  1.00 33.24  ? 66  ALA A CB  1 
ATOM   238   N N   . GLU A 1 48  ? -12.962 -7.345  80.939  1.00 34.81  ? 67  GLU A N   1 
ATOM   239   C CA  . GLU A 1 48  ? -13.961 -7.598  79.917  1.00 36.20  ? 67  GLU A CA  1 
ATOM   240   C C   . GLU A 1 48  ? -13.741 -6.719  78.698  1.00 36.95  ? 67  GLU A C   1 
ATOM   241   O O   . GLU A 1 48  ? -13.912 -7.174  77.566  1.00 38.31  ? 67  GLU A O   1 
ATOM   242   C CB  . GLU A 1 48  ? -15.351 -7.377  80.499  1.00 36.23  ? 67  GLU A CB  1 
ATOM   243   C CG  . GLU A 1 48  ? -16.451 -7.875  79.587  1.00 37.48  ? 67  GLU A CG  1 
ATOM   244   C CD  . GLU A 1 48  ? -17.777 -8.106  80.313  1.00 37.53  ? 67  GLU A CD  1 
ATOM   245   O OE1 . GLU A 1 48  ? -17.787 -7.850  81.549  1.00 37.52  ? 67  GLU A OE1 1 
ATOM   246   O OE2 . GLU A 1 48  ? -18.803 -8.539  79.658  1.00 37.82  ? 67  GLU A OE2 1 
ATOM   247   N N   . PHE A 1 49  ? -13.361 -5.455  78.923  1.00 33.18  ? 68  PHE A N   1 
ATOM   248   C CA  . PHE A 1 49  ? -13.023 -4.523  77.844  1.00 33.71  ? 68  PHE A CA  1 
ATOM   249   C C   . PHE A 1 49  ? -11.930 -5.100  76.953  1.00 34.37  ? 68  PHE A C   1 
ATOM   250   O O   . PHE A 1 49  ? -12.015 -5.057  75.721  1.00 36.06  ? 68  PHE A O   1 
ATOM   251   C CB  . PHE A 1 49  ? -12.588 -3.178  78.477  1.00 33.11  ? 68  PHE A CB  1 
ATOM   252   C CG  . PHE A 1 49  ? -12.067 -2.174  77.486  1.00 33.84  ? 68  PHE A CG  1 
ATOM   253   C CD1 . PHE A 1 49  ? -10.740 -2.148  77.133  1.00 33.72  ? 68  PHE A CD1 1 
ATOM   254   C CD2 . PHE A 1 49  ? -12.932 -1.262  76.887  1.00 34.90  ? 68  PHE A CD2 1 
ATOM   255   C CE1 . PHE A 1 49  ? -10.289 -1.252  76.199  1.00 34.91  ? 68  PHE A CE1 1 
ATOM   256   C CE2 . PHE A 1 49  ? -12.480 -0.356  75.967  1.00 36.11  ? 68  PHE A CE2 1 
ATOM   257   C CZ  . PHE A 1 49  ? -11.176 -0.356  75.615  1.00 35.68  ? 68  PHE A CZ  1 
ATOM   258   N N   . VAL A 1 50  ? -10.895 -5.647  77.569  1.00 33.01  ? 69  VAL A N   1 
ATOM   259   C CA  . VAL A 1 50  ? -9.757  -6.168  76.826  1.00 33.80  ? 69  VAL A CA  1 
ATOM   260   C C   . VAL A 1 50  ? -10.109 -7.495  76.173  1.00 34.98  ? 69  VAL A C   1 
ATOM   261   O O   . VAL A 1 50  ? -9.790  -7.730  75.004  1.00 35.35  ? 69  VAL A O   1 
ATOM   262   C CB  . VAL A 1 50  ? -8.575  -6.302  77.796  1.00 32.81  ? 69  VAL A CB  1 
ATOM   263   C CG1 . VAL A 1 50  ? -7.575  -7.241  77.287  1.00 33.93  ? 69  VAL A CG1 1 
ATOM   264   C CG2 . VAL A 1 50  ? -7.965  -4.927  78.061  1.00 31.47  ? 69  VAL A CG2 1 
ATOM   265   N N   . ALA A 1 51  ? -10.769 -8.380  76.926  1.00 33.44  ? 70  ALA A N   1 
ATOM   266   C CA  . ALA A 1 51  ? -10.989 -9.752  76.469  1.00 33.86  ? 70  ALA A CA  1 
ATOM   267   C C   . ALA A 1 51  ? -12.001 -9.783  75.339  1.00 34.61  ? 70  ALA A C   1 
ATOM   268   O O   . ALA A 1 51  ? -11.935 -10.648 74.468  1.00 35.04  ? 70  ALA A O   1 
ATOM   269   C CB  . ALA A 1 51  ? -11.437 -10.641 77.636  1.00 34.00  ? 70  ALA A CB  1 
ATOM   270   N N   . THR A 1 52  ? -12.896 -8.787  75.316  1.00 33.46  ? 71  THR A N   1 
ATOM   271   C CA  . THR A 1 52  ? -13.903 -8.599  74.286  1.00 34.40  ? 71  THR A CA  1 
ATOM   272   C C   . THR A 1 52  ? -13.391 -7.956  73.016  1.00 34.84  ? 71  THR A C   1 
ATOM   273   O O   . THR A 1 52  ? -14.035 -8.039  71.976  1.00 36.17  ? 71  THR A O   1 
ATOM   274   C CB  . THR A 1 52  ? -14.966 -7.689  74.853  1.00 34.92  ? 71  THR A CB  1 
ATOM   275   O OG1 . THR A 1 52  ? -15.802 -8.424  75.714  1.00 34.83  ? 71  THR A OG1 1 
ATOM   276   C CG2 . THR A 1 52  ? -15.789 -7.129  73.785  1.00 36.05  ? 71  THR A CG2 1 
ATOM   277   N N   . ARG A 1 53  ? -12.307 -7.263  73.083  1.00 33.42  ? 72  ARG A N   1 
ATOM   278   C CA  . ARG A 1 53  ? -11.865 -6.488  71.959  1.00 33.82  ? 72  ARG A CA  1 
ATOM   279   C C   . ARG A 1 53  ? -10.621 -7.065  71.340  1.00 33.24  ? 72  ARG A C   1 
ATOM   280   O O   . ARG A 1 53  ? -10.162 -6.575  70.321  1.00 33.50  ? 72  ARG A O   1 
ATOM   281   C CB  . ARG A 1 53  ? -11.606 -5.033  72.396  1.00 34.18  ? 72  ARG A CB  1 
ATOM   282   C CG  . ARG A 1 53  ? -12.902 -4.273  72.581  1.00 34.48  ? 72  ARG A CG  1 
ATOM   283   C CD  . ARG A 1 53  ? -12.831 -2.972  73.382  1.00 34.63  ? 72  ARG A CD  1 
ATOM   284   N NE  . ARG A 1 53  ? -13.894 -3.021  74.379  1.00 34.12  ? 72  ARG A NE  1 
ATOM   285   C CZ  . ARG A 1 53  ? -14.979 -2.281  74.351  1.00 34.30  ? 72  ARG A CZ  1 
ATOM   286   N NH1 . ARG A 1 53  ? -15.100 -1.299  73.512  1.00 35.24  ? 72  ARG A NH1 1 
ATOM   287   N NH2 . ARG A 1 53  ? -15.958 -2.540  75.195  1.00 34.13  ? 72  ARG A NH2 1 
ATOM   288   N N   . SER A 1 54  ? -10.053 -8.084  71.926  1.00 32.36  ? 73  SER A N   1 
ATOM   289   C CA  . SER A 1 54  ? -8.798  -8.553  71.386  1.00 31.58  ? 73  SER A CA  1 
ATOM   290   C C   . SER A 1 54  ? -8.584  -10.003 71.782  1.00 31.19  ? 73  SER A C   1 
ATOM   291   O O   . SER A 1 54  ? -9.221  -10.523 72.695  1.00 31.84  ? 73  SER A O   1 
ATOM   292   C CB  . SER A 1 54  ? -7.665  -7.670  71.881  1.00 30.81  ? 73  SER A CB  1 
ATOM   293   O OG  . SER A 1 54  ? -6.463  -8.019  71.265  1.00 29.86  ? 73  SER A OG  1 
ATOM   294   N N   . ASN A 1 55  ? -7.692  -10.652 71.060  1.00 32.23  ? 74  ASN A N   1 
ATOM   295   C CA  . ASN A 1 55  ? -7.255  -11.990 71.421  1.00 31.43  ? 74  ASN A CA  1 
ATOM   296   C C   . ASN A 1 55  ? -5.759  -12.011 71.683  1.00 30.16  ? 74  ASN A C   1 
ATOM   297   O O   . ASN A 1 55  ? -5.138  -13.078 71.645  1.00 29.79  ? 74  ASN A O   1 
ATOM   298   C CB  . ASN A 1 55  ? -7.601  -13.012 70.331  1.00 31.55  ? 74  ASN A CB  1 
ATOM   299   C CG  . ASN A 1 55  ? -9.094  -13.290 70.246  1.00 32.78  ? 74  ASN A CG  1 
ATOM   300   O OD1 . ASN A 1 55  ? -9.831  -13.237 71.253  1.00 34.04  ? 74  ASN A OD1 1 
ATOM   301   N ND2 . ASN A 1 55  ? -9.552  -13.543 69.050  1.00 33.65  ? 74  ASN A ND2 1 
ATOM   302   N N   . PHE A 1 56  ? -5.160  -10.860 71.928  1.00 30.30  ? 75  PHE A N   1 
ATOM   303   C CA  . PHE A 1 56  ? -3.702  -10.796 71.930  1.00 28.37  ? 75  PHE A CA  1 
ATOM   304   C C   . PHE A 1 56  ? -3.251  -9.701  72.886  1.00 27.57  ? 75  PHE A C   1 
ATOM   305   O O   . PHE A 1 56  ? -3.364  -8.524  72.555  1.00 28.14  ? 75  PHE A O   1 
ATOM   306   C CB  . PHE A 1 56  ? -3.215  -10.557 70.507  1.00 28.64  ? 75  PHE A CB  1 
ATOM   307   C CG  . PHE A 1 56  ? -1.781  -10.866 70.275  1.00 27.31  ? 75  PHE A CG  1 
ATOM   308   C CD1 . PHE A 1 56  ? -1.074  -11.660 71.121  1.00 26.61  ? 75  PHE A CD1 1 
ATOM   309   C CD2 . PHE A 1 56  ? -1.143  -10.337 69.173  1.00 27.34  ? 75  PHE A CD2 1 
ATOM   310   C CE1 . PHE A 1 56  ? 0.256   -11.919 70.872  1.00 25.74  ? 75  PHE A CE1 1 
ATOM   311   C CE2 . PHE A 1 56  ? 0.186   -10.586 68.916  1.00 26.49  ? 75  PHE A CE2 1 
ATOM   312   C CZ  . PHE A 1 56  ? 0.887   -11.389 69.768  1.00 25.68  ? 75  PHE A CZ  1 
ATOM   313   N N   . ILE A 1 57  ? -2.723  -10.093 74.054  1.00 29.38  ? 76  ILE A N   1 
ATOM   314   C CA  . ILE A 1 57  ? -2.260  -9.137  75.045  1.00 28.08  ? 76  ILE A CA  1 
ATOM   315   C C   . ILE A 1 57  ? -0.911  -9.535  75.628  1.00 26.61  ? 76  ILE A C   1 
ATOM   316   O O   . ILE A 1 57  ? -0.722  -10.672 76.065  1.00 26.92  ? 76  ILE A O   1 
ATOM   317   C CB  . ILE A 1 57  ? -3.250  -8.987  76.209  1.00 28.65  ? 76  ILE A CB  1 
ATOM   318   C CG1 . ILE A 1 57  ? -2.774  -7.856  77.117  1.00 27.38  ? 76  ILE A CG1 1 
ATOM   319   C CG2 . ILE A 1 57  ? -3.334  -10.282 77.000  1.00 29.05  ? 76  ILE A CG2 1 
ATOM   320   C CD1 . ILE A 1 57  ? -3.828  -7.288  78.062  1.00 28.12  ? 76  ILE A CD1 1 
ATOM   321   N N   . CYS A 1 58  ? -0.006  -8.568  75.725  1.00 32.62  ? 77  CYS A N   1 
ATOM   322   C CA  . CYS A 1 58  ? 1.218   -8.751  76.476  1.00 31.25  ? 77  CYS A CA  1 
ATOM   323   C C   . CYS A 1 58  ? 1.118   -7.953  77.768  1.00 31.02  ? 77  CYS A C   1 
ATOM   324   O O   . CYS A 1 58  ? 0.758   -6.775  77.754  1.00 31.05  ? 77  CYS A O   1 
ATOM   325   C CB  . CYS A 1 58  ? 2.451   -8.327  75.688  1.00 30.69  ? 77  CYS A CB  1 
ATOM   326   S SG  . CYS A 1 58  ? 3.943   -8.476  76.763  1.00 29.94  ? 77  CYS A SG  1 
ATOM   327   N N   . LEU A 1 59  ? 1.363   -8.604  78.888  1.00 28.36  ? 78  LEU A N   1 
ATOM   328   C CA  . LEU A 1 59  ? 1.227   -7.964  80.194  1.00 27.82  ? 78  LEU A CA  1 
ATOM   329   C C   . LEU A 1 59  ? 2.619   -7.551  80.658  1.00 27.20  ? 78  LEU A C   1 
ATOM   330   O O   . LEU A 1 59  ? 3.556   -8.366  80.640  1.00 27.48  ? 78  LEU A O   1 
ATOM   331   C CB  . LEU A 1 59  ? 0.560   -8.871  81.229  1.00 28.41  ? 78  LEU A CB  1 
ATOM   332   C CG  . LEU A 1 59  ? -0.903  -9.211  80.943  1.00 29.54  ? 78  LEU A CG  1 
ATOM   333   C CD1 . LEU A 1 59  ? -1.375  -10.351 81.865  1.00 30.30  ? 78  LEU A CD1 1 
ATOM   334   C CD2 . LEU A 1 59  ? -1.740  -8.021  81.181  1.00 29.60  ? 78  LEU A CD2 1 
ATOM   335   N N   . GLU A 1 60  ? 2.749   -6.287  81.035  1.00 26.62  ? 79  GLU A N   1 
ATOM   336   C CA  . GLU A 1 60  ? 4.033   -5.667  81.318  1.00 26.50  ? 79  GLU A CA  1 
ATOM   337   C C   . GLU A 1 60  ? 4.570   -6.015  82.708  1.00 26.88  ? 79  GLU A C   1 
ATOM   338   O O   . GLU A 1 60  ? 3.842   -6.403  83.641  1.00 27.32  ? 79  GLU A O   1 
ATOM   339   C CB  . GLU A 1 60  ? 3.904   -4.134  81.212  1.00 27.05  ? 79  GLU A CB  1 
ATOM   340   C CG  . GLU A 1 60  ? 4.269   -3.564  79.852  1.00 28.05  ? 79  GLU A CG  1 
ATOM   341   C CD  . GLU A 1 60  ? 5.798   -3.558  79.610  1.00 28.60  ? 79  GLU A CD  1 
ATOM   342   O OE1 . GLU A 1 60  ? 6.579   -3.754  80.569  1.00 28.59  ? 79  GLU A OE1 1 
ATOM   343   O OE2 . GLU A 1 60  ? 6.220   -3.385  78.438  1.00 29.54  ? 79  GLU A OE2 1 
ATOM   344   N N   . LYS A 1 61  ? 5.888   -5.847  82.827  1.00 26.18  ? 80  LYS A N   1 
ATOM   345   C CA  . LYS A 1 61  ? 6.577   -5.792  84.120  1.00 26.99  ? 80  LYS A CA  1 
ATOM   346   C C   . LYS A 1 61  ? 5.808   -4.911  85.095  1.00 27.71  ? 80  LYS A C   1 
ATOM   347   O O   . LYS A 1 61  ? 5.345   -3.819  84.746  1.00 27.76  ? 80  LYS A O   1 
ATOM   348   C CB  . LYS A 1 61  ? 8.002   -5.243  83.936  1.00 28.21  ? 80  LYS A CB  1 
ATOM   349   C CG  . LYS A 1 61  ? 8.000   -3.750  83.630  1.00 29.31  ? 80  LYS A CG  1 
ATOM   350   C CD  . LYS A 1 61  ? 9.402   -3.153  83.540  1.00 30.28  ? 80  LYS A CD  1 
ATOM   351   C CE  . LYS A 1 61  ? 10.036  -3.287  82.128  1.00 30.37  ? 80  LYS A CE  1 
ATOM   352   N NZ  . LYS A 1 61  ? 9.254   -2.749  80.908  1.00 30.61  ? 80  LYS A NZ  1 
ATOM   353   N N   . GLY A 1 62  ? 5.687   -5.415  86.311  1.00 25.67  ? 81  GLY A N   1 
ATOM   354   C CA  . GLY A 1 62  ? 4.979   -4.765  87.360  1.00 26.35  ? 81  GLY A CA  1 
ATOM   355   C C   . GLY A 1 62  ? 3.557   -5.206  87.539  1.00 25.69  ? 81  GLY A C   1 
ATOM   356   O O   . GLY A 1 62  ? 2.957   -4.906  88.573  1.00 26.64  ? 81  GLY A O   1 
ATOM   357   N N   . HIS A 1 63  ? 2.993   -5.922  86.593  1.00 26.90  ? 82  HIS A N   1 
ATOM   358   C CA  . HIS A 1 63  ? 1.547   -6.062  86.610  1.00 26.45  ? 82  HIS A CA  1 
ATOM   359   C C   . HIS A 1 63  ? 1.080   -6.683  87.919  1.00 27.20  ? 82  HIS A C   1 
ATOM   360   O O   . HIS A 1 63  ? 1.510   -7.762  88.298  1.00 27.96  ? 82  HIS A O   1 
ATOM   361   C CB  . HIS A 1 63  ? 1.062   -6.865  85.409  1.00 26.02  ? 82  HIS A CB  1 
ATOM   362   C CG  . HIS A 1 63  ? -0.423  -6.995  85.374  1.00 25.99  ? 82  HIS A CG  1 
ATOM   363   N ND1 . HIS A 1 63  ? -1.239  -5.950  85.005  1.00 26.14  ? 82  HIS A ND1 1 
ATOM   364   C CD2 . HIS A 1 63  ? -1.240  -7.999  85.764  1.00 26.52  ? 82  HIS A CD2 1 
ATOM   365   C CE1 . HIS A 1 63  ? -2.498  -6.331  85.104  1.00 26.62  ? 82  HIS A CE1 1 
ATOM   366   N NE2 . HIS A 1 63  ? -2.526  -7.572  85.563  1.00 26.78  ? 82  HIS A NE2 1 
ATOM   367   N N   . ALA A 1 64  ? 0.244   -5.948  88.613  1.00 26.35  ? 83  ALA A N   1 
ATOM   368   C CA  . ALA A 1 64  ? -0.416  -6.277  89.861  1.00 26.92  ? 83  ALA A CA  1 
ATOM   369   C C   . ALA A 1 64  ? 0.541   -6.461  91.010  1.00 28.32  ? 83  ALA A C   1 
ATOM   370   O O   . ALA A 1 64  ? 0.155   -7.055  92.025  1.00 29.53  ? 83  ALA A O   1 
ATOM   371   C CB  . ALA A 1 64  ? -1.294  -7.513  89.710  1.00 27.27  ? 83  ALA A CB  1 
ATOM   372   N N   . THR A 1 65  ? 1.773   -5.932  90.907  1.00 27.31  ? 84  THR A N   1 
ATOM   373   C CA  . THR A 1 65  ? 2.730   -6.174  91.985  1.00 28.76  ? 84  THR A CA  1 
ATOM   374   C C   . THR A 1 65  ? 2.246   -5.611  93.327  1.00 29.86  ? 84  THR A C   1 
ATOM   375   O O   . THR A 1 65  ? 2.621   -6.114  94.386  1.00 31.34  ? 84  THR A O   1 
ATOM   376   C CB  . THR A 1 65  ? 4.120   -5.631  91.672  1.00 29.79  ? 84  THR A CB  1 
ATOM   377   O OG1 . THR A 1 65  ? 4.034   -4.359  91.050  1.00 29.40  ? 84  THR A OG1 1 
ATOM   378   C CG2 . THR A 1 65  ? 4.926   -6.629  90.767  1.00 29.35  ? 84  THR A CG2 1 
ATOM   379   N N   . ARG A 1 66  ? 1.390   -4.610  93.322  1.00 30.53  ? 85  ARG A N   1 
ATOM   380   C CA  . ARG A 1 66  ? 0.976   -4.073  94.615  1.00 31.58  ? 85  ARG A CA  1 
ATOM   381   C C   . ARG A 1 66  ? 0.162   -5.091  95.398  1.00 31.85  ? 85  ARG A C   1 
ATOM   382   O O   . ARG A 1 66  ? 0.254   -5.157  96.621  1.00 33.48  ? 85  ARG A O   1 
ATOM   383   C CB  . ARG A 1 66  ? 0.181   -2.792  94.431  1.00 31.64  ? 85  ARG A CB  1 
ATOM   384   C CG  . ARG A 1 66  ? -0.284  -2.204  95.716  1.00 33.29  ? 85  ARG A CG  1 
ATOM   385   C CD  . ARG A 1 66  ? -1.240  -1.100  95.431  1.00 33.71  ? 85  ARG A CD  1 
ATOM   386   N NE  . ARG A 1 66  ? -0.456  0.013   94.917  1.00 34.65  ? 85  ARG A NE  1 
ATOM   387   C CZ  . ARG A 1 66  ? -0.910  1.246   94.761  1.00 35.87  ? 85  ARG A CZ  1 
ATOM   388   N NH1 . ARG A 1 66  ? -2.173  1.548   95.008  1.00 36.58  ? 85  ARG A NH1 1 
ATOM   389   N NH2 . ARG A 1 66  ? -0.077  2.196   94.350  1.00 36.33  ? 85  ARG A NH2 1 
ATOM   390   N N   . THR A 1 67  ? -0.655  -5.871  94.719  1.00 29.39  ? 86  THR A N   1 
ATOM   391   C CA  . THR A 1 67  ? -1.502  -6.847  95.395  1.00 29.91  ? 86  THR A CA  1 
ATOM   392   C C   . THR A 1 67  ? -0.942  -8.260  95.386  1.00 30.73  ? 86  THR A C   1 
ATOM   393   O O   . THR A 1 67  ? -1.318  -9.051  96.251  1.00 32.13  ? 86  THR A O   1 
ATOM   394   C CB  . THR A 1 67  ? -2.899  -6.862  94.761  1.00 29.52  ? 86  THR A CB  1 
ATOM   395   O OG1 . THR A 1 67  ? -2.784  -7.113  93.358  1.00 28.61  ? 86  THR A OG1 1 
ATOM   396   C CG2 . THR A 1 67  ? -3.543  -5.529  95.029  1.00 29.81  ? 86  THR A CG2 1 
ATOM   397   N N   . HIS A 1 68  ? -0.036  -8.571  94.469  1.00 29.97  ? 87  HIS A N   1 
ATOM   398   C CA  . HIS A 1 68  ? 0.429   -9.927  94.264  1.00 30.72  ? 87  HIS A CA  1 
ATOM   399   C C   . HIS A 1 68  ? 1.927   -10.050 94.398  1.00 32.05  ? 87  HIS A C   1 
ATOM   400   O O   . HIS A 1 68  ? 2.465   -11.123 94.110  1.00 33.00  ? 87  HIS A O   1 
ATOM   401   C CB  . HIS A 1 68  ? 0.029   -10.410 92.880  1.00 29.78  ? 87  HIS A CB  1 
ATOM   402   C CG  . HIS A 1 68  ? -1.417  -10.730 92.777  1.00 29.51  ? 87  HIS A CG  1 
ATOM   403   N ND1 . HIS A 1 68  ? -2.400  -9.815  93.101  1.00 29.14  ? 87  HIS A ND1 1 
ATOM   404   C CD2 . HIS A 1 68  ? -2.058  -11.889 92.461  1.00 30.34  ? 87  HIS A CD2 1 
ATOM   405   C CE1 . HIS A 1 68  ? -3.584  -10.377 92.938  1.00 29.39  ? 87  HIS A CE1 1 
ATOM   406   N NE2 . HIS A 1 68  ? -3.405  -11.631 92.541  1.00 30.24  ? 87  HIS A NE2 1 
ATOM   407   N N   . GLY A 1 69  ? 2.613   -8.978  94.761  1.00 29.79  ? 88  GLY A N   1 
ATOM   408   C CA  . GLY A 1 69  ? 4.013   -9.083  95.117  1.00 31.22  ? 88  GLY A CA  1 
ATOM   409   C C   . GLY A 1 69  ? 4.992   -9.132  93.994  1.00 31.54  ? 88  GLY A C   1 
ATOM   410   O O   . GLY A 1 69  ? 5.934   -8.338  93.951  1.00 33.31  ? 88  GLY A O   1 
ATOM   411   N N   . THR A 1 70  ? 4.815   -10.052 93.063  1.00 31.96  ? 89  THR A N   1 
ATOM   412   C CA  . THR A 1 70  ? 5.713   -10.138 91.923  1.00 31.21  ? 89  THR A CA  1 
ATOM   413   C C   . THR A 1 70  ? 4.932   -10.091 90.618  1.00 28.89  ? 89  THR A C   1 
ATOM   414   O O   . THR A 1 70  ? 3.718   -10.254 90.586  1.00 28.35  ? 89  THR A O   1 
ATOM   415   C CB  . THR A 1 70  ? 6.524   -11.433 91.957  1.00 33.19  ? 89  THR A CB  1 
ATOM   416   O OG1 . THR A 1 70  ? 5.598   -12.530 91.956  1.00 33.34  ? 89  THR A OG1 1 
ATOM   417   C CG2 . THR A 1 70  ? 7.377   -11.500 93.226  1.00 35.42  ? 89  THR A CG2 1 
ATOM   418   N N   . THR A 1 71  ? 5.682   -9.922  89.539  1.00 30.16  ? 90  THR A N   1 
ATOM   419   C CA  . THR A 1 71  ? 5.121   -9.856  88.199  1.00 28.43  ? 90  THR A CA  1 
ATOM   420   C C   . THR A 1 71  ? 4.590   -11.212 87.761  1.00 28.85  ? 90  THR A C   1 
ATOM   421   O O   . THR A 1 71  ? 3.524   -11.313 87.126  1.00 28.24  ? 90  THR A O   1 
ATOM   422   C CB  . THR A 1 71  ? 6.218   -9.318  87.274  1.00 27.73  ? 90  THR A CB  1 
ATOM   423   O OG1 . THR A 1 71  ? 6.516   -7.919  87.588  1.00 27.87  ? 90  THR A OG1 1 
ATOM   424   C CG2 . THR A 1 71  ? 5.838   -9.429  85.856  1.00 26.57  ? 90  THR A CG2 1 
ATOM   425   N N   . GLU A 1 72  ? 5.318   -12.269 88.093  1.00 28.19  ? 91  GLU A N   1 
ATOM   426   C CA  . GLU A 1 72  ? 4.903   -13.617 87.740  1.00 28.70  ? 91  GLU A CA  1 
ATOM   427   C C   . GLU A 1 72  ? 3.587   -13.956 88.409  1.00 29.61  ? 91  GLU A C   1 
ATOM   428   O O   . GLU A 1 72  ? 2.690   -14.538 87.791  1.00 29.64  ? 91  GLU A O   1 
ATOM   429   C CB  . GLU A 1 72  ? 6.009   -14.588 88.143  1.00 30.37  ? 91  GLU A CB  1 
ATOM   430   C CG  . GLU A 1 72  ? 7.374   -14.245 87.501  1.00 29.92  ? 91  GLU A CG  1 
ATOM   431   C CD  . GLU A 1 72  ? 8.415   -13.658 88.493  1.00 30.08  ? 91  GLU A CD  1 
ATOM   432   O OE1 . GLU A 1 72  ? 8.031   -12.832 89.409  1.00 29.90  ? 91  GLU A OE1 1 
ATOM   433   O OE2 . GLU A 1 72  ? 9.637   -14.012 88.338  1.00 30.97  ? 91  GLU A OE2 1 
ATOM   434   N N   . ALA A 1 73  ? 3.418   -13.555 89.658  1.00 28.43  ? 92  ALA A N   1 
ATOM   435   C CA  . ALA A 1 73  ? 2.155   -13.856 90.320  1.00 28.90  ? 92  ALA A CA  1 
ATOM   436   C C   . ALA A 1 73  ? 1.028   -13.006 89.752  1.00 27.09  ? 92  ALA A C   1 
ATOM   437   O O   . ALA A 1 73  ? -0.101  -13.482 89.595  1.00 27.48  ? 92  ALA A O   1 
ATOM   438   C CB  . ALA A 1 73  ? 2.282   -13.664 91.822  1.00 30.35  ? 92  ALA A CB  1 
ATOM   439   N N   . GLY A 1 74  ? 1.314   -11.742 89.424  1.00 28.91  ? 93  GLY A N   1 
ATOM   440   C CA  . GLY A 1 74  ? 0.259   -10.876 88.929  1.00 27.84  ? 93  GLY A CA  1 
ATOM   441   C C   . GLY A 1 74  ? -0.190  -11.295 87.550  1.00 27.17  ? 93  GLY A C   1 
ATOM   442   O O   . GLY A 1 74  ? -1.381  -11.408 87.282  1.00 27.50  ? 93  GLY A O   1 
ATOM   443   N N   . ILE A 1 75  ? 0.773   -11.549 86.671  1.00 27.29  ? 94  ILE A N   1 
ATOM   444   C CA  . ILE A 1 75  ? 0.472   -11.932 85.300  1.00 27.11  ? 94  ILE A CA  1 
ATOM   445   C C   . ILE A 1 75  ? -0.257  -13.272 85.254  1.00 28.76  ? 94  ILE A C   1 
ATOM   446   O O   . ILE A 1 75  ? -1.227  -13.436 84.507  1.00 29.36  ? 94  ILE A O   1 
ATOM   447   C CB  . ILE A 1 75  ? 1.770   -11.971 84.456  1.00 26.34  ? 94  ILE A CB  1 
ATOM   448   C CG1 . ILE A 1 75  ? 2.301   -10.536 84.281  1.00 25.24  ? 94  ILE A CG1 1 
ATOM   449   C CG2 . ILE A 1 75  ? 1.487   -12.765 83.152  1.00 27.03  ? 94  ILE A CG2 1 
ATOM   450   C CD1 . ILE A 1 75  ? 3.558   -10.447 83.424  1.00 24.87  ? 94  ILE A CD1 1 
ATOM   451   N N   . GLU A 1 76  ? 0.205   -14.246 86.046  1.00 26.71  ? 95  GLU A N   1 
ATOM   452   C CA  . GLU A 1 76  ? -0.473  -15.532 86.152  1.00 28.73  ? 95  GLU A CA  1 
ATOM   453   C C   . GLU A 1 76  ? -1.935  -15.363 86.541  1.00 29.11  ? 95  GLU A C   1 
ATOM   454   O O   . GLU A 1 76  ? -2.840  -15.977 85.945  1.00 30.55  ? 95  GLU A O   1 
ATOM   455   C CB  . GLU A 1 76  ? 0.246   -16.396 87.187  1.00 30.58  ? 95  GLU A CB  1 
ATOM   456   C CG  . GLU A 1 76  ? -0.442  -17.724 87.424  1.00 32.08  ? 95  GLU A CG  1 
ATOM   457   C CD  . GLU A 1 76  ? -0.498  -18.633 86.153  1.00 32.44  ? 95  GLU A CD  1 
ATOM   458   O OE1 . GLU A 1 76  ? 0.317   -18.384 85.197  1.00 31.52  ? 95  GLU A OE1 1 
ATOM   459   O OE2 . GLU A 1 76  ? -1.346  -19.575 86.121  1.00 33.80  ? 95  GLU A OE2 1 
ATOM   460   N N   . ALA A 1 77  ? -2.177  -14.547 87.569  1.00 28.08  ? 96  ALA A N   1 
ATOM   461   C CA  . ALA A 1 77  ? -3.534  -14.269 88.001  1.00 28.21  ? 96  ALA A CA  1 
ATOM   462   C C   . ALA A 1 77  ? -4.326  -13.566 86.915  1.00 27.88  ? 96  ALA A C   1 
ATOM   463   O O   . ALA A 1 77  ? -5.525  -13.814 86.744  1.00 28.76  ? 96  ALA A O   1 
ATOM   464   C CB  . ALA A 1 77  ? -3.506  -13.415 89.265  1.00 27.89  ? 96  ALA A CB  1 
ATOM   465   N N   . GLU A 1 78  ? -3.685  -12.668 86.185  1.00 28.86  ? 97  GLU A N   1 
ATOM   466   C CA  . GLU A 1 78  ? -4.397  -11.900 85.176  1.00 28.65  ? 97  GLU A CA  1 
ATOM   467   C C   . GLU A 1 78  ? -4.711  -12.781 83.978  1.00 30.02  ? 97  GLU A C   1 
ATOM   468   O O   . GLU A 1 78  ? -5.832  -12.775 83.461  1.00 31.31  ? 97  GLU A O   1 
ATOM   469   C CB  . GLU A 1 78  ? -3.574  -10.676 84.750  1.00 27.22  ? 97  GLU A CB  1 
ATOM   470   C CG  . GLU A 1 78  ? -4.390  -9.701  83.901  1.00 27.10  ? 97  GLU A CG  1 
ATOM   471   C CD  . GLU A 1 78  ? -5.552  -9.113  84.696  1.00 27.47  ? 97  GLU A CD  1 
ATOM   472   O OE1 . GLU A 1 78  ? -5.235  -8.355  85.668  1.00 26.50  ? 97  GLU A OE1 1 
ATOM   473   O OE2 . GLU A 1 78  ? -6.757  -9.420  84.395  1.00 29.02  ? 97  GLU A OE2 1 
ATOM   474   N N   . ALA A 1 79  ? -3.722  -13.559 83.537  1.00 27.85  ? 98  ALA A N   1 
ATOM   475   C CA  . ALA A 1 79  ? -3.951  -14.563 82.501  1.00 29.48  ? 98  ALA A CA  1 
ATOM   476   C C   . ALA A 1 79  ? -5.174  -15.412 82.819  1.00 30.87  ? 98  ALA A C   1 
ATOM   477   O O   . ALA A 1 79  ? -6.028  -15.650 81.958  1.00 32.09  ? 98  ALA A O   1 
ATOM   478   C CB  . ALA A 1 79  ? -2.721  -15.445 82.344  1.00 29.28  ? 98  ALA A CB  1 
ATOM   479   N N   . ARG A 1 80  ? -5.287  -15.863 84.068  1.00 28.89  ? 99  ARG A N   1 
ATOM   480   C CA  . ARG A 1 80  ? -6.460  -16.649 84.451  1.00 30.43  ? 99  ARG A CA  1 
ATOM   481   C C   . ARG A 1 80  ? -7.749  -15.851 84.281  1.00 30.24  ? 99  ARG A C   1 
ATOM   482   O O   . ARG A 1 80  ? -8.731  -16.363 83.721  1.00 31.48  ? 99  ARG A O   1 
ATOM   483   C CB  . ARG A 1 80  ? -6.339  -17.140 85.886  1.00 30.95  ? 99  ARG A CB  1 
ATOM   484   C CG  . ARG A 1 80  ? -5.362  -18.228 86.015  1.00 32.43  ? 99  ARG A CG  1 
ATOM   485   C CD  . ARG A 1 80  ? -5.043  -18.500 87.470  1.00 33.15  ? 99  ARG A CD  1 
ATOM   486   N NE  . ARG A 1 80  ? -3.855  -19.333 87.606  1.00 34.86  ? 99  ARG A NE  1 
ATOM   487   C CZ  . ARG A 1 80  ? -3.680  -20.242 88.557  1.00 37.59  ? 99  ARG A CZ  1 
ATOM   488   N NH1 . ARG A 1 80  ? -4.603  -20.464 89.479  1.00 38.75  ? 99  ARG A NH1 1 
ATOM   489   N NH2 . ARG A 1 80  ? -2.555  -20.950 88.571  1.00 38.65  ? 99  ARG A NH2 1 
ATOM   490   N N   . GLN A 1 81  ? -7.783  -14.579 84.735  1.00 30.23  ? 100 GLN A N   1 
ATOM   491   C CA  . GLN A 1 81  ? -9.093  -13.904 84.675  1.00 30.36  ? 100 GLN A CA  1 
ATOM   492   C C   . GLN A 1 81  ? -9.467  -13.548 83.249  1.00 30.93  ? 100 GLN A C   1 
ATOM   493   O O   . GLN A 1 81  ? -10.650 -13.554 82.915  1.00 31.79  ? 100 GLN A O   1 
ATOM   494   C CB  . GLN A 1 81  ? -9.193  -12.701 85.609  1.00 29.97  ? 100 GLN A CB  1 
ATOM   495   C CG  . GLN A 1 81  ? -8.735  -11.402 85.144  1.00 29.42  ? 100 GLN A CG  1 
ATOM   496   C CD  . GLN A 1 81  ? -9.271  -10.221 86.010  1.00 28.69  ? 100 GLN A CD  1 
ATOM   497   O OE1 . GLN A 1 81  ? -10.416 -10.239 86.547  1.00 29.92  ? 100 GLN A OE1 1 
ATOM   498   N NE2 . GLN A 1 81  ? -8.429  -9.209  86.154  1.00 26.94  ? 100 GLN A NE2 1 
ATOM   499   N N   . LEU A 1 82  ? -8.466  -13.300 82.404  1.00 29.76  ? 101 LEU A N   1 
ATOM   500   C CA  . LEU A 1 82  ? -8.712  -12.933 81.016  1.00 30.60  ? 101 LEU A CA  1 
ATOM   501   C C   . LEU A 1 82  ? -9.210  -14.143 80.243  1.00 32.09  ? 101 LEU A C   1 
ATOM   502   O O   . LEU A 1 82  ? -10.162 -14.064 79.463  1.00 32.63  ? 101 LEU A O   1 
ATOM   503   C CB  . LEU A 1 82  ? -7.437  -12.373 80.361  1.00 29.90  ? 101 LEU A CB  1 
ATOM   504   C CG  . LEU A 1 82  ? -7.004  -10.949 80.728  1.00 28.19  ? 101 LEU A CG  1 
ATOM   505   C CD1 . LEU A 1 82  ? -5.747  -10.449 79.964  1.00 27.35  ? 101 LEU A CD1 1 
ATOM   506   C CD2 . LEU A 1 82  ? -8.161  -9.976  80.537  1.00 29.10  ? 101 LEU A CD2 1 
ATOM   507   N N   . LYS A 1 83  ? -8.571  -15.282 80.471  1.00 32.43  ? 102 LYS A N   1 
ATOM   508   C CA  . LYS A 1 83  ? -8.915  -16.481 79.736  1.00 33.37  ? 102 LYS A CA  1 
ATOM   509   C C   . LYS A 1 83  ? -10.262 -17.037 80.157  1.00 34.12  ? 102 LYS A C   1 
ATOM   510   O O   . LYS A 1 83  ? -10.883 -17.740 79.356  1.00 35.01  ? 102 LYS A O   1 
ATOM   511   C CB  . LYS A 1 83  ? -7.801  -17.486 79.902  1.00 33.85  ? 102 LYS A CB  1 
ATOM   512   C CG  . LYS A 1 83  ? -6.845  -17.498 78.751  1.00 33.51  ? 102 LYS A CG  1 
ATOM   513   C CD  . LYS A 1 83  ? -5.569  -18.191 79.182  1.00 34.49  ? 102 LYS A CD  1 
ATOM   514   C CE  . LYS A 1 83  ? -4.587  -18.273 78.030  1.00 33.44  ? 102 LYS A CE  1 
ATOM   515   N NZ  . LYS A 1 83  ? -3.740  -19.502 78.145  1.00 32.58  ? 102 LYS A NZ  1 
ATOM   516   N N   . ASN A 1 84  ? -10.731 -16.704 81.373  1.00 30.64  ? 103 ASN A N   1 
ATOM   517   C CA  . ASN A 1 84  ? -12.059 -17.107 81.807  1.00 31.21  ? 103 ASN A CA  1 
ATOM   518   C C   . ASN A 1 84  ? -13.111 -16.338 81.033  1.00 30.95  ? 103 ASN A C   1 
ATOM   519   O O   . ASN A 1 84  ? -14.211 -16.845 80.794  1.00 31.84  ? 103 ASN A O   1 
ATOM   520   C CB  . ASN A 1 84  ? -12.205 -16.900 83.313  1.00 31.64  ? 103 ASN A CB  1 
ATOM   521   C CG  . ASN A 1 84  ? -13.621 -17.076 83.783  1.00 33.25  ? 103 ASN A CG  1 
ATOM   522   O OD1 . ASN A 1 84  ? -14.160 -18.125 83.676  1.00 34.63  ? 103 ASN A OD1 1 
ATOM   523   N ND2 . ASN A 1 84  ? -14.222 -16.043 84.325  1.00 33.17  ? 103 ASN A ND2 1 
ATOM   524   N N   . LEU A 1 85  ? -12.778 -15.110 80.630  1.00 31.77  ? 104 LEU A N   1 
ATOM   525   C CA  . LEU A 1 85  ? -13.637 -14.217 79.886  1.00 31.85  ? 104 LEU A CA  1 
ATOM   526   C C   . LEU A 1 85  ? -13.554 -14.460 78.383  1.00 32.60  ? 104 LEU A C   1 
ATOM   527   O O   . LEU A 1 85  ? -14.578 -14.511 77.712  1.00 33.55  ? 104 LEU A O   1 
ATOM   528   C CB  . LEU A 1 85  ? -13.238 -12.802 80.229  1.00 31.25  ? 104 LEU A CB  1 
ATOM   529   C CG  . LEU A 1 85  ? -13.450 -12.349 81.661  1.00 30.59  ? 104 LEU A CG  1 
ATOM   530   C CD1 . LEU A 1 85  ? -12.863 -10.897 81.742  1.00 29.65  ? 104 LEU A CD1 1 
ATOM   531   C CD2 . LEU A 1 85  ? -14.888 -12.421 82.097  1.00 31.05  ? 104 LEU A CD2 1 
ATOM   532   N N   . ASN A 1 86  ? -12.355 -14.600 77.837  1.00 31.58  ? 105 ASN A N   1 
ATOM   533   C CA  . ASN A 1 86  ? -12.188 -14.962 76.426  1.00 32.40  ? 105 ASN A CA  1 
ATOM   534   C C   . ASN A 1 86  ? -11.219 -16.134 76.272  1.00 33.22  ? 105 ASN A C   1 
ATOM   535   O O   . ASN A 1 86  ? -9.986  -15.954 76.346  1.00 32.76  ? 105 ASN A O   1 
ATOM   536   C CB  . ASN A 1 86  ? -11.728 -13.758 75.603  1.00 31.70  ? 105 ASN A CB  1 
ATOM   537   C CG  . ASN A 1 86  ? -11.323 -14.131 74.207  1.00 32.67  ? 105 ASN A CG  1 
ATOM   538   O OD1 . ASN A 1 86  ? -11.871 -15.076 73.652  1.00 33.83  ? 105 ASN A OD1 1 
ATOM   539   N ND2 . ASN A 1 86  ? -10.383 -13.409 73.627  1.00 32.25  ? 105 ASN A ND2 1 
ATOM   540   N N   . PRO A 1 87  ? -11.747 -17.327 75.988  1.00 33.97  ? 106 PRO A N   1 
ATOM   541   C CA  . PRO A 1 87  ? -10.909 -18.539 75.989  1.00 34.79  ? 106 PRO A CA  1 
ATOM   542   C C   . PRO A 1 87  ? -9.884  -18.629 74.867  1.00 35.23  ? 106 PRO A C   1 
ATOM   543   O O   . PRO A 1 87  ? -8.850  -19.280 75.061  1.00 35.58  ? 106 PRO A O   1 
ATOM   544   C CB  . PRO A 1 87  ? -11.921 -19.673 75.870  1.00 35.93  ? 106 PRO A CB  1 
ATOM   545   C CG  . PRO A 1 87  ? -13.271 -19.053 75.927  1.00 35.69  ? 106 PRO A CG  1 
ATOM   546   C CD  . PRO A 1 87  ? -13.187 -17.605 75.909  1.00 34.52  ? 106 PRO A CD  1 
ATOM   547   N N   . LYS A 1 88  ? -10.116 -17.989 73.723  1.00 36.57  ? 107 LYS A N   1 
ATOM   548   C CA  . LYS A 1 88  ? -9.096  -17.834 72.685  1.00 37.26  ? 107 LYS A CA  1 
ATOM   549   C C   . LYS A 1 88  ? -8.056  -16.735 72.975  1.00 36.04  ? 107 LYS A C   1 
ATOM   550   O O   . LYS A 1 88  ? -7.263  -16.384 72.085  1.00 36.56  ? 107 LYS A O   1 
ATOM   551   C CB  . LYS A 1 88  ? -9.751  -17.506 71.330  1.00 38.83  ? 107 LYS A CB  1 
ATOM   552   C CG  . LYS A 1 88  ? -10.641 -18.551 70.827  1.00 41.12  ? 107 LYS A CG  1 
ATOM   553   C CD  . LYS A 1 88  ? -11.948 -17.958 70.381  1.00 41.67  ? 107 LYS A CD  1 
ATOM   554   C CE  . LYS A 1 88  ? -12.715 -17.273 71.575  1.00 41.31  ? 107 LYS A CE  1 
ATOM   555   N NZ  . LYS A 1 88  ? -13.764 -18.176 72.281  1.00 41.62  ? 107 LYS A NZ  1 
ATOM   556   N N   . MET A 1 89  ? -8.020  -16.184 74.171  1.00 37.08  ? 108 MET A N   1 
ATOM   557   C CA  . MET A 1 89  ? -7.047  -15.139 74.456  1.00 35.51  ? 108 MET A CA  1 
ATOM   558   C C   . MET A 1 89  ? -5.621  -15.661 74.576  1.00 35.55  ? 108 MET A C   1 
ATOM   559   O O   . MET A 1 89  ? -5.357  -16.611 75.310  1.00 36.85  ? 108 MET A O   1 
ATOM   560   C CB  . MET A 1 89  ? -7.437  -14.445 75.750  1.00 34.39  ? 108 MET A CB  1 
ATOM   561   C CG  . MET A 1 89  ? -6.526  -13.354 76.118  1.00 33.10  ? 108 MET A CG  1 
ATOM   562   S SD  . MET A 1 89  ? -7.121  -11.829 75.385  1.00 32.83  ? 108 MET A SD  1 
ATOM   563   C CE  . MET A 1 89  ? -7.787  -11.090 76.867  1.00 31.79  ? 108 MET A CE  1 
ATOM   564   N N   . LYS A 1 90  ? -4.695  -14.981 73.902  1.00 32.13  ? 109 LYS A N   1 
ATOM   565   C CA  . LYS A 1 90  ? -3.266  -15.222 74.041  1.00 31.72  ? 109 LYS A CA  1 
ATOM   566   C C   . LYS A 1 90  ? -2.696  -14.185 74.980  1.00 29.38  ? 109 LYS A C   1 
ATOM   567   O O   . LYS A 1 90  ? -2.747  -12.987 74.677  1.00 28.49  ? 109 LYS A O   1 
ATOM   568   C CB  . LYS A 1 90  ? -2.528  -15.147 72.714  1.00 32.76  ? 109 LYS A CB  1 
ATOM   569   C CG  . LYS A 1 90  ? -3.062  -16.098 71.673  1.00 35.59  ? 109 LYS A CG  1 
ATOM   570   C CD  . LYS A 1 90  ? -2.893  -17.543 72.120  1.00 37.20  ? 109 LYS A CD  1 
ATOM   571   C CE  . LYS A 1 90  ? -3.391  -18.446 71.010  1.00 39.55  ? 109 LYS A CE  1 
ATOM   572   N NZ  . LYS A 1 90  ? -3.174  -19.826 71.383  1.00 40.92  ? 109 LYS A NZ  1 
ATOM   573   N N   . VAL A 1 91  ? -2.111  -14.651 76.085  1.00 31.57  ? 110 VAL A N   1 
ATOM   574   C CA  . VAL A 1 91  ? -1.549  -13.803 77.111  1.00 29.60  ? 110 VAL A CA  1 
ATOM   575   C C   . VAL A 1 91  ? -0.070  -14.041 77.150  1.00 29.14  ? 110 VAL A C   1 
ATOM   576   O O   . VAL A 1 91  ? 0.367   -15.179 77.312  1.00 30.07  ? 110 VAL A O   1 
ATOM   577   C CB  . VAL A 1 91  ? -2.196  -14.042 78.463  1.00 29.42  ? 110 VAL A CB  1 
ATOM   578   C CG1 . VAL A 1 91  ? -1.662  -13.024 79.482  1.00 27.98  ? 110 VAL A CG1 1 
ATOM   579   C CG2 . VAL A 1 91  ? -3.686  -13.923 78.267  1.00 30.32  ? 110 VAL A CG2 1 
ATOM   580   N N   . ILE A 1 92  ? 0.702   -12.971 76.972  1.00 29.54  ? 111 ILE A N   1 
ATOM   581   C CA  . ILE A 1 92  ? 2.141   -13.043 76.779  1.00 29.14  ? 111 ILE A CA  1 
ATOM   582   C C   . ILE A 1 92  ? 2.820   -12.497 78.023  1.00 27.57  ? 111 ILE A C   1 
ATOM   583   O O   . ILE A 1 92  ? 2.481   -11.408 78.507  1.00 26.93  ? 111 ILE A O   1 
ATOM   584   C CB  . ILE A 1 92  ? 2.586   -12.279 75.529  1.00 29.23  ? 111 ILE A CB  1 
ATOM   585   C CG1 . ILE A 1 92  ? 1.792   -12.732 74.330  1.00 30.83  ? 111 ILE A CG1 1 
ATOM   586   C CG2 . ILE A 1 92  ? 4.029   -12.562 75.250  1.00 28.96  ? 111 ILE A CG2 1 
ATOM   587   C CD1 . ILE A 1 92  ? 1.917   -14.247 74.095  1.00 32.64  ? 111 ILE A CD1 1 
ATOM   588   N N   . PHE A 1 93  ? 3.753   -13.285 78.547  1.00 28.45  ? 112 PHE A N   1 
ATOM   589   C CA  . PHE A 1 93  ? 4.535   -12.957 79.718  1.00 27.52  ? 112 PHE A CA  1 
ATOM   590   C C   . PHE A 1 93  ? 5.718   -12.077 79.326  1.00 26.51  ? 112 PHE A C   1 
ATOM   591   O O   . PHE A 1 93  ? 6.530   -12.464 78.467  1.00 27.36  ? 112 PHE A O   1 
ATOM   592   C CB  . PHE A 1 93  ? 5.014   -14.251 80.348  1.00 28.32  ? 112 PHE A CB  1 
ATOM   593   C CG  . PHE A 1 93  ? 5.918   -14.058 81.492  1.00 27.98  ? 112 PHE A CG  1 
ATOM   594   C CD1 . PHE A 1 93  ? 5.400   -13.798 82.749  1.00 28.14  ? 112 PHE A CD1 1 
ATOM   595   C CD2 . PHE A 1 93  ? 7.288   -14.176 81.336  1.00 28.42  ? 112 PHE A CD2 1 
ATOM   596   C CE1 . PHE A 1 93  ? 6.241   -13.637 83.843  1.00 28.14  ? 112 PHE A CE1 1 
ATOM   597   C CE2 . PHE A 1 93  ? 8.137   -14.064 82.434  1.00 28.61  ? 112 PHE A CE2 1 
ATOM   598   C CZ  . PHE A 1 93  ? 7.611   -13.778 83.686  1.00 28.18  ? 112 PHE A CZ  1 
ATOM   599   N N   . TYR A 1 94  ? 5.818   -10.912 79.965  1.00 28.33  ? 113 TYR A N   1 
ATOM   600   C CA  . TYR A 1 94  ? 6.878   -9.963  79.687  1.00 28.03  ? 113 TYR A CA  1 
ATOM   601   C C   . TYR A 1 94  ? 8.152   -10.420 80.391  1.00 28.30  ? 113 TYR A C   1 
ATOM   602   O O   . TYR A 1 94  ? 8.146   -10.656 81.600  1.00 28.40  ? 113 TYR A O   1 
ATOM   603   C CB  . TYR A 1 94  ? 6.460   -8.547  80.171  1.00 27.66  ? 113 TYR A CB  1 
ATOM   604   C CG  . TYR A 1 94  ? 7.554   -7.546  79.872  1.00 27.76  ? 113 TYR A CG  1 
ATOM   605   C CD1 . TYR A 1 94  ? 8.606   -7.393  80.732  1.00 27.82  ? 113 TYR A CD1 1 
ATOM   606   C CD2 . TYR A 1 94  ? 7.590   -6.852  78.667  1.00 28.23  ? 113 TYR A CD2 1 
ATOM   607   C CE1 . TYR A 1 94  ? 9.639   -6.562  80.438  1.00 28.19  ? 113 TYR A CE1 1 
ATOM   608   C CE2 . TYR A 1 94  ? 8.641   -5.992  78.369  1.00 28.67  ? 113 TYR A CE2 1 
ATOM   609   C CZ  . TYR A 1 94  ? 9.669   -5.875  79.274  1.00 28.50  ? 113 TYR A CZ  1 
ATOM   610   O OH  . TYR A 1 94  ? 10.740  -5.054  79.046  1.00 29.44  ? 113 TYR A OH  1 
ATOM   611   N N   . TRP A 1 95  ? 9.245   -10.572 79.641  1.00 26.36  ? 114 TRP A N   1 
ATOM   612   C CA  . TRP A 1 95  ? 10.483  -11.109 80.230  1.00 26.68  ? 114 TRP A CA  1 
ATOM   613   C C   . TRP A 1 95  ? 11.673  -10.534 79.454  1.00 27.24  ? 114 TRP A C   1 
ATOM   614   O O   . TRP A 1 95  ? 11.998  -11.006 78.362  1.00 27.96  ? 114 TRP A O   1 
ATOM   615   C CB  . TRP A 1 95  ? 10.475  -12.643 80.255  1.00 27.64  ? 114 TRP A CB  1 
ATOM   616   C CG  . TRP A 1 95  ? 11.663  -13.292 80.993  1.00 28.17  ? 114 TRP A CG  1 
ATOM   617   C CD1 . TRP A 1 95  ? 12.444  -14.320 80.534  1.00 29.12  ? 114 TRP A CD1 1 
ATOM   618   C CD2 . TRP A 1 95  ? 12.187  -12.984 82.300  1.00 28.31  ? 114 TRP A CD2 1 
ATOM   619   N NE1 . TRP A 1 95  ? 13.423  -14.654 81.452  1.00 30.09  ? 114 TRP A NE1 1 
ATOM   620   C CE2 . TRP A 1 95  ? 13.288  -13.848 82.536  1.00 29.77  ? 114 TRP A CE2 1 
ATOM   621   C CE3 . TRP A 1 95  ? 11.851  -12.066 83.289  1.00 27.93  ? 114 TRP A CE3 1 
ATOM   622   C CZ2 . TRP A 1 95  ? 14.045  -13.785 83.693  1.00 31.00  ? 114 TRP A CZ2 1 
ATOM   623   C CZ3 . TRP A 1 95  ? 12.608  -12.025 84.443  1.00 29.21  ? 114 TRP A CZ3 1 
ATOM   624   C CH2 . TRP A 1 95  ? 13.676  -12.862 84.632  1.00 30.77  ? 114 TRP A CH2 1 
ATOM   625   N N   . ASN A 1 96  ? 12.340  -9.540  80.056  1.00 27.04  ? 115 ASN A N   1 
ATOM   626   C CA  . ASN A 1 96  ? 13.391  -8.777  79.397  1.00 27.62  ? 115 ASN A CA  1 
ATOM   627   C C   . ASN A 1 96  ? 14.656  -9.606  79.219  1.00 28.44  ? 115 ASN A C   1 
ATOM   628   O O   . ASN A 1 96  ? 15.207  -10.154 80.184  1.00 28.88  ? 115 ASN A O   1 
ATOM   629   C CB  . ASN A 1 96  ? 13.694  -7.520  80.223  1.00 27.61  ? 115 ASN A CB  1 
ATOM   630   C CG  . ASN A 1 96  ? 14.553  -6.515  79.478  1.00 28.70  ? 115 ASN A CG  1 
ATOM   631   O OD1 . ASN A 1 96  ? 15.783  -6.699  79.270  1.00 29.75  ? 115 ASN A OD1 1 
ATOM   632   N ND2 . ASN A 1 96  ? 13.912  -5.450  79.051  1.00 28.90  ? 115 ASN A ND2 1 
ATOM   633   N N   . THR A 1 97  ? 15.146  -9.625  77.973  1.00 28.42  ? 116 THR A N   1 
ATOM   634   C CA  . THR A 1 97  ? 16.275  -10.444 77.554  1.00 29.17  ? 116 THR A CA  1 
ATOM   635   C C   . THR A 1 97  ? 17.598  -9.938  78.065  1.00 30.20  ? 116 THR A C   1 
ATOM   636   O O   . THR A 1 97  ? 18.550  -10.724 78.115  1.00 31.21  ? 116 THR A O   1 
ATOM   637   C CB  . THR A 1 97  ? 16.341  -10.488 76.026  1.00 29.62  ? 116 THR A CB  1 
ATOM   638   O OG1 . THR A 1 97  ? 14.999  -10.662 75.525  1.00 29.28  ? 116 THR A OG1 1 
ATOM   639   C CG2 . THR A 1 97  ? 17.233  -11.617 75.479  1.00 30.92  ? 116 THR A CG2 1 
ATOM   640   N N   . PHE A 1 98  ? 17.684  -8.642  78.445  1.00 28.20  ? 117 PHE A N   1 
ATOM   641   C CA  . PHE A 1 98  ? 18.951  -7.961  78.712  1.00 29.45  ? 117 PHE A CA  1 
ATOM   642   C C   . PHE A 1 98  ? 19.064  -7.410  80.111  1.00 29.90  ? 117 PHE A C   1 
ATOM   643   O O   . PHE A 1 98  ? 20.181  -7.189  80.565  1.00 31.74  ? 117 PHE A O   1 
ATOM   644   C CB  . PHE A 1 98  ? 19.117  -6.783  77.736  1.00 30.36  ? 117 PHE A CB  1 
ATOM   645   C CG  . PHE A 1 98  ? 20.554  -6.338  77.488  1.00 31.74  ? 117 PHE A CG  1 
ATOM   646   C CD1 . PHE A 1 98  ? 21.646  -7.165  77.764  1.00 32.78  ? 117 PHE A CD1 1 
ATOM   647   C CD2 . PHE A 1 98  ? 20.786  -5.091  76.902  1.00 32.89  ? 117 PHE A CD2 1 
ATOM   648   C CE1 . PHE A 1 98  ? 22.907  -6.744  77.478  1.00 34.00  ? 117 PHE A CE1 1 
ATOM   649   C CE2 . PHE A 1 98  ? 22.040  -4.670  76.615  1.00 34.24  ? 117 PHE A CE2 1 
ATOM   650   C CZ  . PHE A 1 98  ? 23.109  -5.482  76.907  1.00 34.68  ? 117 PHE A CZ  1 
ATOM   651   N N   . LEU A 1 99  ? 17.946  -7.176  80.795  1.00 31.29  ? 118 LEU A N   1 
ATOM   652   C CA  . LEU A 1 99  ? 17.938  -6.322  81.970  1.00 31.68  ? 118 LEU A CA  1 
ATOM   653   C C   . LEU A 1 99  ? 17.292  -7.032  83.149  1.00 31.26  ? 118 LEU A C   1 
ATOM   654   O O   . LEU A 1 99  ? 16.232  -7.647  83.011  1.00 29.96  ? 118 LEU A O   1 
ATOM   655   C CB  . LEU A 1 99  ? 17.167  -5.007  81.754  1.00 31.26  ? 118 LEU A CB  1 
ATOM   656   C CG  . LEU A 1 99  ? 17.577  -4.178  80.557  1.00 32.41  ? 118 LEU A CG  1 
ATOM   657   C CD1 . LEU A 1 99  ? 16.691  -2.952  80.507  1.00 32.55  ? 118 LEU A CD1 1 
ATOM   658   C CD2 . LEU A 1 99  ? 19.015  -3.804  80.598  1.00 34.66  ? 118 LEU A CD2 1 
ATOM   659   N N   . ASP A 1 100 ? 17.896  -6.837  84.323  1.00 31.85  ? 119 ASP A N   1 
ATOM   660   C CA  . ASP A 1 100 ? 17.513  -7.485  85.565  1.00 31.80  ? 119 ASP A CA  1 
ATOM   661   C C   . ASP A 1 100 ? 16.559  -6.565  86.319  1.00 30.74  ? 119 ASP A C   1 
ATOM   662   O O   . ASP A 1 100 ? 16.929  -5.818  87.217  1.00 32.11  ? 119 ASP A O   1 
ATOM   663   C CB  . ASP A 1 100 ? 18.787  -7.813  86.338  1.00 34.07  ? 119 ASP A CB  1 
ATOM   664   C CG  . ASP A 1 100 ? 18.550  -8.083  87.787  1.00 34.73  ? 119 ASP A CG  1 
ATOM   665   O OD1 . ASP A 1 100 ? 17.472  -8.552  88.135  1.00 33.64  ? 119 ASP A OD1 1 
ATOM   666   O OD2 . ASP A 1 100 ? 19.459  -7.853  88.594  1.00 36.27  ? 119 ASP A OD2 1 
ATOM   667   N N   . TYR A 1 101 ? 15.300  -6.590  85.921  1.00 32.08  ? 120 TYR A N   1 
ATOM   668   C CA  . TYR A 1 101 ? 14.301  -5.776  86.592  1.00 31.15  ? 120 TYR A CA  1 
ATOM   669   C C   . TYR A 1 101 ? 14.024  -6.346  87.961  1.00 31.35  ? 120 TYR A C   1 
ATOM   670   O O   . TYR A 1 101 ? 14.153  -7.535  88.189  1.00 31.86  ? 120 TYR A O   1 
ATOM   671   C CB  . TYR A 1 101 ? 13.010  -5.677  85.773  1.00 29.92  ? 120 TYR A CB  1 
ATOM   672   C CG  . TYR A 1 101 ? 13.128  -4.669  84.649  1.00 29.83  ? 120 TYR A CG  1 
ATOM   673   C CD1 . TYR A 1 101 ? 13.132  -3.302  84.912  1.00 30.61  ? 120 TYR A CD1 1 
ATOM   674   C CD2 . TYR A 1 101 ? 13.264  -5.091  83.329  1.00 30.24  ? 120 TYR A CD2 1 
ATOM   675   C CE1 . TYR A 1 101 ? 13.274  -2.378  83.883  1.00 31.31  ? 120 TYR A CE1 1 
ATOM   676   C CE2 . TYR A 1 101 ? 13.387  -4.183  82.283  1.00 30.88  ? 120 TYR A CE2 1 
ATOM   677   C CZ  . TYR A 1 101 ? 13.402  -2.820  82.581  1.00 31.45  ? 120 TYR A CZ  1 
ATOM   678   O OH  . TYR A 1 101 ? 13.534  -1.915  81.578  1.00 32.89  ? 120 TYR A OH  1 
ATOM   679   N N   . SER A 1 102 ? 13.670  -5.472  88.889  1.00 32.40  ? 121 SER A N   1 
ATOM   680   C CA  . SER A 1 102 ? 13.612  -5.846  90.285  1.00 33.22  ? 121 SER A CA  1 
ATOM   681   C C   . SER A 1 102 ? 12.288  -6.496  90.613  1.00 32.28  ? 121 SER A C   1 
ATOM   682   O O   . SER A 1 102 ? 12.217  -7.319  91.532  1.00 33.73  ? 121 SER A O   1 
ATOM   683   C CB  . SER A 1 102 ? 13.817  -4.609  91.164  1.00 34.07  ? 121 SER A CB  1 
ATOM   684   O OG  . SER A 1 102 ? 12.801  -3.635  90.925  1.00 33.37  ? 121 SER A OG  1 
ATOM   685   N N   . MET A 1 103 ? 11.242  -6.171  89.859  1.00 31.08  ? 122 MET A N   1 
ATOM   686   C CA  . MET A 1 103 ? 9.891   -6.509  90.267  1.00 30.40  ? 122 MET A CA  1 
ATOM   687   C C   . MET A 1 103 ? 9.469   -7.931  89.845  1.00 30.38  ? 122 MET A C   1 
ATOM   688   O O   . MET A 1 103 ? 8.274   -8.213  89.734  1.00 30.02  ? 122 MET A O   1 
ATOM   689   C CB  . MET A 1 103 ? 8.953   -5.424  89.743  1.00 30.13  ? 122 MET A CB  1 
ATOM   690   C CG  . MET A 1 103 ? 8.751   -5.384  88.270  1.00 30.30  ? 122 MET A CG  1 
ATOM   691   S SD  . MET A 1 103 ? 9.976   -4.462  87.374  1.00 30.54  ? 122 MET A SD  1 
ATOM   692   C CE  . MET A 1 103 ? 10.014  -2.871  88.192  1.00 31.61  ? 122 MET A CE  1 
ATOM   693   N N   . PHE A 1 104 ? 10.431  -8.815  89.639  1.00 30.04  ? 123 PHE A N   1 
ATOM   694   C CA  . PHE A 1 104 ? 10.177  -10.233 89.455  1.00 30.56  ? 123 PHE A CA  1 
ATOM   695   C C   . PHE A 1 104 ? 10.784  -11.027 90.609  1.00 32.13  ? 123 PHE A C   1 
ATOM   696   O O   . PHE A 1 104 ? 11.861  -10.695 91.096  1.00 33.09  ? 123 PHE A O   1 
ATOM   697   C CB  . PHE A 1 104 ? 10.791  -10.736 88.146  1.00 30.64  ? 123 PHE A CB  1 
ATOM   698   C CG  . PHE A 1 104 ? 10.229  -10.112 86.917  1.00 29.00  ? 123 PHE A CG  1 
ATOM   699   C CD1 . PHE A 1 104 ? 10.406  -8.789  86.639  1.00 28.55  ? 123 PHE A CD1 1 
ATOM   700   C CD2 . PHE A 1 104 ? 9.575   -10.874 86.006  1.00 29.10  ? 123 PHE A CD2 1 
ATOM   701   C CE1 . PHE A 1 104 ? 9.890   -8.247  85.483  1.00 28.04  ? 123 PHE A CE1 1 
ATOM   702   C CE2 . PHE A 1 104 ? 9.055   -10.349 84.856  1.00 28.38  ? 123 PHE A CE2 1 
ATOM   703   C CZ  . PHE A 1 104 ? 9.224   -9.058  84.578  1.00 27.91  ? 123 PHE A CZ  1 
ATOM   704   N N   . ALA A 1 105 ? 10.109  -12.112 91.007  1.00 28.97  ? 124 ALA A N   1 
ATOM   705   C CA  . ALA A 1 105 ? 10.733  -13.109 91.882  1.00 31.23  ? 124 ALA A CA  1 
ATOM   706   C C   . ALA A 1 105 ? 12.069  -13.615 91.349  1.00 32.30  ? 124 ALA A C   1 
ATOM   707   O O   . ALA A 1 105 ? 12.994  -13.865 92.120  1.00 34.02  ? 124 ALA A O   1 
ATOM   708   C CB  . ALA A 1 105 ? 9.813   -14.314 92.068  1.00 32.19  ? 124 ALA A CB  1 
ATOM   709   N N   . ALA A 1 106 ? 12.179  -13.793 90.036  1.00 29.96  ? 125 ALA A N   1 
ATOM   710   C CA  . ALA A 1 106 ? 13.444  -14.239 89.457  1.00 31.42  ? 125 ALA A CA  1 
ATOM   711   C C   . ALA A 1 106 ? 14.591  -13.330 89.855  1.00 31.84  ? 125 ALA A C   1 
ATOM   712   O O   . ALA A 1 106 ? 15.737  -13.762 89.937  1.00 33.82  ? 125 ALA A O   1 
ATOM   713   C CB  . ALA A 1 106 ? 13.354  -14.293 87.920  1.00 30.73  ? 125 ALA A CB  1 
ATOM   714   N N   . HIS A 1 107 ? 14.313  -12.063 90.099  1.00 30.44  ? 126 HIS A N   1 
ATOM   715   C CA  . HIS A 1 107 ? 15.396  -11.144 90.446  1.00 31.28  ? 126 HIS A CA  1 
ATOM   716   C C   . HIS A 1 107 ? 16.150  -11.601 91.717  1.00 33.36  ? 126 HIS A C   1 
ATOM   717   O O   . HIS A 1 107 ? 17.382  -11.475 91.806  1.00 34.80  ? 126 HIS A O   1 
ATOM   718   C CB  . HIS A 1 107 ? 14.854  -9.711  90.630  1.00 29.70  ? 126 HIS A CB  1 
ATOM   719   C CG  . HIS A 1 107 ? 15.865  -8.834  91.276  1.00 30.83  ? 126 HIS A CG  1 
ATOM   720   N ND1 . HIS A 1 107 ? 17.005  -8.449  90.606  1.00 31.70  ? 126 HIS A ND1 1 
ATOM   721   C CD2 . HIS A 1 107 ? 16.024  -8.451  92.562  1.00 31.71  ? 126 HIS A CD2 1 
ATOM   722   C CE1 . HIS A 1 107 ? 17.794  -7.813  91.438  1.00 32.88  ? 126 HIS A CE1 1 
ATOM   723   N NE2 . HIS A 1 107 ? 17.226  -7.809  92.633  1.00 32.73  ? 126 HIS A NE2 1 
ATOM   724   N N   . LYS A 1 108 ? 15.432  -12.116 92.715  1.00 34.10  ? 127 LYS A N   1 
ATOM   725   C CA  . LYS A 1 108 ? 16.160  -12.571 93.890  1.00 35.73  ? 127 LYS A CA  1 
ATOM   726   C C   . LYS A 1 108 ? 16.950  -13.845 93.623  1.00 37.98  ? 127 LYS A C   1 
ATOM   727   O O   . LYS A 1 108 ? 17.890  -14.105 94.350  1.00 39.67  ? 127 LYS A O   1 
ATOM   728   C CB  . LYS A 1 108 ? 15.259  -12.781 95.110  1.00 35.57  ? 127 LYS A CB  1 
ATOM   729   C CG  . LYS A 1 108 ? 13.844  -13.025 94.789  1.00 34.72  ? 127 LYS A CG  1 
ATOM   730   C CD  . LYS A 1 108 ? 13.052  -13.345 96.034  1.00 34.56  ? 127 LYS A CD  1 
ATOM   731   C CE  . LYS A 1 108 ? 12.749  -12.130 96.874  1.00 33.94  ? 127 LYS A CE  1 
ATOM   732   N NZ  . LYS A 1 108 ? 11.993  -12.679 98.110  1.00 34.13  ? 127 LYS A NZ  1 
ATOM   733   N N   . GLU A 1 109 ? 16.621  -14.614 92.575  1.00 31.81  ? 128 GLU A N   1 
ATOM   734   C CA  . GLU A 1 109 ? 17.477  -15.716 92.139  1.00 33.66  ? 128 GLU A CA  1 
ATOM   735   C C   . GLU A 1 109 ? 18.698  -15.169 91.400  1.00 34.07  ? 128 GLU A C   1 
ATOM   736   O O   . GLU A 1 109 ? 19.815  -15.625 91.630  1.00 35.86  ? 128 GLU A O   1 
ATOM   737   C CB  . GLU A 1 109 ? 16.687  -16.725 91.276  1.00 33.74  ? 128 GLU A CB  1 
ATOM   738   N N   . TYR A 1 110 ? 18.513  -14.150 90.543  1.00 32.18  ? 129 TYR A N   1 
ATOM   739   C CA  . TYR A 1 110 ? 19.651  -13.613 89.786  1.00 32.85  ? 129 TYR A CA  1 
ATOM   740   C C   . TYR A 1 110 ? 20.635  -12.911 90.709  1.00 34.33  ? 129 TYR A C   1 
ATOM   741   O O   . TYR A 1 110 ? 21.824  -12.829 90.399  1.00 35.57  ? 129 TYR A O   1 
ATOM   742   C CB  . TYR A 1 110 ? 19.181  -12.656 88.676  1.00 30.38  ? 129 TYR A CB  1 
ATOM   743   C CG  . TYR A 1 110 ? 20.330  -12.151 87.812  1.00 31.26  ? 129 TYR A CG  1 
ATOM   744   C CD1 . TYR A 1 110 ? 20.850  -12.914 86.796  1.00 31.42  ? 129 TYR A CD1 1 
ATOM   745   C CD2 . TYR A 1 110 ? 20.910  -10.922 88.032  1.00 31.46  ? 129 TYR A CD2 1 
ATOM   746   C CE1 . TYR A 1 110 ? 21.913  -12.471 86.041  1.00 32.13  ? 129 TYR A CE1 1 
ATOM   747   C CE2 . TYR A 1 110 ? 21.962  -10.481 87.262  1.00 32.80  ? 129 TYR A CE2 1 
ATOM   748   C CZ  . TYR A 1 110 ? 22.464  -11.263 86.284  1.00 32.61  ? 129 TYR A CZ  1 
ATOM   749   O OH  . TYR A 1 110 ? 23.504  -10.835 85.509  1.00 33.22  ? 129 TYR A OH  1 
ATOM   750   N N   . ALA A 1 111 ? 20.150  -12.395 91.851  1.00 34.89  ? 130 ALA A N   1 
ATOM   751   C CA  . ALA A 1 111 ? 21.011  -11.705 92.810  1.00 35.51  ? 130 ALA A CA  1 
ATOM   752   C C   . ALA A 1 111 ? 22.045  -12.636 93.404  1.00 37.35  ? 130 ALA A C   1 
ATOM   753   O O   . ALA A 1 111 ? 23.141  -12.196 93.752  1.00 38.19  ? 130 ALA A O   1 
ATOM   754   C CB  . ALA A 1 111 ? 20.176  -11.094 93.935  1.00 34.32  ? 130 ALA A CB  1 
ATOM   755   N N   . LYS A 1 112 ? 21.722  -13.930 93.521  1.00 36.68  ? 131 LYS A N   1 
ATOM   756   C CA  . LYS A 1 112 ? 22.582  -14.937 94.153  1.00 38.21  ? 131 LYS A CA  1 
ATOM   757   C C   . LYS A 1 112 ? 23.579  -15.572 93.208  1.00 39.53  ? 131 LYS A C   1 
ATOM   758   O O   . LYS A 1 112 ? 24.295  -16.475 93.622  1.00 40.47  ? 131 LYS A O   1 
ATOM   759   C CB  . LYS A 1 112 ? 21.701  -16.038 94.770  1.00 38.36  ? 131 LYS A CB  1 
ATOM   760   C CG  . LYS A 1 112 ? 20.617  -15.401 95.639  1.00 36.92  ? 131 LYS A CG  1 
ATOM   761   C CD  . LYS A 1 112 ? 19.926  -16.291 96.660  1.00 37.04  ? 131 LYS A CD  1 
ATOM   762   C CE  . LYS A 1 112 ? 18.739  -17.068 96.153  1.00 36.81  ? 131 LYS A CE  1 
ATOM   763   N NZ  . LYS A 1 112 ? 19.066  -18.207 95.217  1.00 37.69  ? 131 LYS A NZ  1 
ATOM   764   N N   . HIS A 1 113 ? 23.660  -15.140 91.953  1.00 37.71  ? 132 HIS A N   1 
ATOM   765   C CA  . HIS A 1 113 ? 24.581  -15.727 90.986  1.00 37.79  ? 132 HIS A CA  1 
ATOM   766   C C   . HIS A 1 113 ? 25.532  -14.671 90.448  1.00 37.87  ? 132 HIS A C   1 
ATOM   767   O O   . HIS A 1 113 ? 25.579  -14.425 89.241  1.00 36.51  ? 132 HIS A O   1 
ATOM   768   C CB  . HIS A 1 113 ? 23.810  -16.415 89.869  1.00 37.42  ? 132 HIS A CB  1 
ATOM   769   C CG  . HIS A 1 113 ? 23.087  -17.640 90.339  1.00 38.01  ? 132 HIS A CG  1 
ATOM   770   N ND1 . HIS A 1 113 ? 23.626  -18.911 90.261  1.00 38.79  ? 132 HIS A ND1 1 
ATOM   771   C CD2 . HIS A 1 113 ? 21.879  -17.777 90.938  1.00 38.10  ? 132 HIS A CD2 1 
ATOM   772   C CE1 . HIS A 1 113 ? 22.763  -19.776 90.768  1.00 39.36  ? 132 HIS A CE1 1 
ATOM   773   N NE2 . HIS A 1 113 ? 21.698  -19.115 91.191  1.00 39.20  ? 132 HIS A NE2 1 
ATOM   774   N N   . PRO A 1 114 ? 26.332  -14.062 91.316  1.00 36.53  ? 133 PRO A N   1 
ATOM   775   C CA  . PRO A 1 114 ? 27.263  -13.031 90.851  1.00 36.68  ? 133 PRO A CA  1 
ATOM   776   C C   . PRO A 1 114 ? 28.302  -13.545 89.917  1.00 36.64  ? 133 PRO A C   1 
ATOM   777   O O   . PRO A 1 114 ? 28.924  -12.753 89.217  1.00 36.27  ? 133 PRO A O   1 
ATOM   778   C CB  . PRO A 1 114 ? 27.904  -12.538 92.143  1.00 37.58  ? 133 PRO A CB  1 
ATOM   779   C CG  . PRO A 1 114 ? 27.755  -13.695 93.080  1.00 37.89  ? 133 PRO A CG  1 
ATOM   780   C CD  . PRO A 1 114 ? 26.410  -14.257 92.773  1.00 37.18  ? 133 PRO A CD  1 
ATOM   781   N N   . GLN A 1 115 ? 28.546  -14.844 89.897  1.00 37.07  ? 134 GLN A N   1 
ATOM   782   C CA  . GLN A 1 115 ? 29.457  -15.404 88.902  1.00 37.14  ? 134 GLN A CA  1 
ATOM   783   C C   . GLN A 1 115 ? 28.946  -15.158 87.483  1.00 35.68  ? 134 GLN A C   1 
ATOM   784   O O   . GLN A 1 115 ? 29.745  -15.175 86.535  1.00 35.86  ? 134 GLN A O   1 
ATOM   785   C CB  . GLN A 1 115 ? 29.651  -16.895 89.208  1.00 38.62  ? 134 GLN A CB  1 
ATOM   786   C CG  . GLN A 1 115 ? 28.337  -17.633 89.168  1.00 39.57  ? 134 GLN A CG  1 
ATOM   787   C CD  . GLN A 1 115 ? 27.684  -17.862 90.516  1.00 40.37  ? 134 GLN A CD  1 
ATOM   788   O OE1 . GLN A 1 115 ? 27.830  -17.075 91.469  1.00 39.61  ? 134 GLN A OE1 1 
ATOM   789   N NE2 . GLN A 1 115 ? 26.900  -18.937 90.580  1.00 40.71  ? 134 GLN A NE2 1 
ATOM   790   N N   . TRP A 1 116 ? 27.654  -14.859 87.324  1.00 37.26  ? 135 TRP A N   1 
ATOM   791   C CA  . TRP A 1 116 ? 27.114  -14.557 85.993  1.00 36.19  ? 135 TRP A CA  1 
ATOM   792   C C   . TRP A 1 116 ? 27.173  -13.072 85.609  1.00 35.60  ? 135 TRP A C   1 
ATOM   793   O O   . TRP A 1 116 ? 27.080  -12.747 84.425  1.00 34.48  ? 135 TRP A O   1 
ATOM   794   C CB  . TRP A 1 116 ? 25.643  -14.991 85.872  1.00 35.45  ? 135 TRP A CB  1 
ATOM   795   C CG  . TRP A 1 116 ? 25.323  -16.452 86.175  1.00 35.60  ? 135 TRP A CG  1 
ATOM   796   C CD1 . TRP A 1 116 ? 26.190  -17.532 86.179  1.00 36.13  ? 135 TRP A CD1 1 
ATOM   797   C CD2 . TRP A 1 116 ? 24.042  -16.976 86.531  1.00 35.09  ? 135 TRP A CD2 1 
ATOM   798   N NE1 . TRP A 1 116 ? 25.512  -18.669 86.516  1.00 36.28  ? 135 TRP A NE1 1 
ATOM   799   C CE2 . TRP A 1 116 ? 24.197  -18.360 86.743  1.00 35.72  ? 135 TRP A CE2 1 
ATOM   800   C CE3 . TRP A 1 116 ? 22.783  -16.402 86.704  1.00 34.63  ? 135 TRP A CE3 1 
ATOM   801   C CZ2 . TRP A 1 116 ? 23.149  -19.168 87.106  1.00 35.86  ? 135 TRP A CZ2 1 
ATOM   802   C CZ3 . TRP A 1 116 ? 21.753  -17.204 87.083  1.00 34.88  ? 135 TRP A CZ3 1 
ATOM   803   C CH2 . TRP A 1 116 ? 21.933  -18.573 87.271  1.00 35.50  ? 135 TRP A CH2 1 
ATOM   804   N N   . TRP A 1 117 ? 27.347  -12.166 86.563  1.00 36.00  ? 136 TRP A N   1 
ATOM   805   C CA  . TRP A 1 117 ? 27.086  -10.762 86.297  1.00 35.20  ? 136 TRP A CA  1 
ATOM   806   C C   . TRP A 1 117 ? 28.019  -10.214 85.225  1.00 35.26  ? 136 TRP A C   1 
ATOM   807   O O   . TRP A 1 117 ? 29.221  -10.480 85.220  1.00 36.23  ? 136 TRP A O   1 
ATOM   808   C CB  . TRP A 1 117 ? 27.237  -9.981  87.592  1.00 36.16  ? 136 TRP A CB  1 
ATOM   809   C CG  . TRP A 1 117 ? 26.199  -10.304 88.592  1.00 36.45  ? 136 TRP A CG  1 
ATOM   810   C CD1 . TRP A 1 117 ? 25.128  -11.092 88.416  1.00 36.12  ? 136 TRP A CD1 1 
ATOM   811   C CD2 . TRP A 1 117 ? 26.137  -9.833  89.936  1.00 36.56  ? 136 TRP A CD2 1 
ATOM   812   N NE1 . TRP A 1 117 ? 24.385  -11.138 89.558  1.00 36.31  ? 136 TRP A NE1 1 
ATOM   813   C CE2 . TRP A 1 117 ? 24.997  -10.376 90.512  1.00 36.50  ? 136 TRP A CE2 1 
ATOM   814   C CE3 . TRP A 1 117 ? 26.940  -8.995  90.702  1.00 37.24  ? 136 TRP A CE3 1 
ATOM   815   C CZ2 . TRP A 1 117 ? 24.631  -10.117 91.809  1.00 36.72  ? 136 TRP A CZ2 1 
ATOM   816   C CZ3 . TRP A 1 117 ? 26.565  -8.721  91.987  1.00 37.27  ? 136 TRP A CZ3 1 
ATOM   817   C CH2 . TRP A 1 117 ? 25.419  -9.279  92.529  1.00 37.20  ? 136 TRP A CH2 1 
ATOM   818   N N   . LEU A 1 118 ? 27.451  -9.407  84.335  1.00 36.85  ? 137 LEU A N   1 
ATOM   819   C CA  . LEU A 1 118 ? 28.211  -8.816  83.244  1.00 36.77  ? 137 LEU A CA  1 
ATOM   820   C C   . LEU A 1 118 ? 29.039  -7.626  83.739  1.00 37.67  ? 137 LEU A C   1 
ATOM   821   O O   . LEU A 1 118 ? 28.531  -6.741  84.449  1.00 37.62  ? 137 LEU A O   1 
ATOM   822   C CB  . LEU A 1 118 ? 27.268  -8.380  82.114  1.00 35.45  ? 137 LEU A CB  1 
ATOM   823   C CG  . LEU A 1 118 ? 27.924  -7.797  80.855  1.00 35.30  ? 137 LEU A CG  1 
ATOM   824   C CD1 . LEU A 1 118 ? 28.848  -8.774  80.183  1.00 35.72  ? 137 LEU A CD1 1 
ATOM   825   C CD2 . LEU A 1 118 ? 26.854  -7.341  79.898  1.00 34.34  ? 137 LEU A CD2 1 
ATOM   826   N N   . ARG A 1 119 ? 30.296  -7.595  83.326  1.00 38.43  ? 138 ARG A N   1 
ATOM   827   C CA  . ARG A 1 119 ? 31.246  -6.566  83.695  1.00 39.14  ? 138 ARG A CA  1 
ATOM   828   C C   . ARG A 1 119 ? 31.778  -5.911  82.434  1.00 38.85  ? 138 ARG A C   1 
ATOM   829   O O   . ARG A 1 119 ? 31.766  -6.501  81.355  1.00 38.78  ? 138 ARG A O   1 
ATOM   830   C CB  . ARG A 1 119 ? 32.424  -7.142  84.484  1.00 40.51  ? 138 ARG A CB  1 
ATOM   831   C CG  . ARG A 1 119 ? 32.033  -7.763  85.767  1.00 40.87  ? 138 ARG A CG  1 
ATOM   832   C CD  . ARG A 1 119 ? 33.199  -8.441  86.472  1.00 41.92  ? 138 ARG A CD  1 
ATOM   833   N NE  . ARG A 1 119 ? 32.639  -9.229  87.559  1.00 42.09  ? 138 ARG A NE  1 
ATOM   834   C CZ  . ARG A 1 119 ? 32.259  -8.727  88.725  1.00 42.08  ? 138 ARG A CZ  1 
ATOM   835   N NH1 . ARG A 1 119 ? 32.520  -7.475  89.051  1.00 41.85  ? 138 ARG A NH1 1 
ATOM   836   N NH2 . ARG A 1 119 ? 31.585  -9.494  89.573  1.00 42.46  ? 138 ARG A NH2 1 
ATOM   837   N N   . THR A 1 120 ? 32.274  -4.695  82.575  1.00 42.80  ? 139 THR A N   1 
ATOM   838   C CA  . THR A 1 120 ? 32.924  -4.059  81.447  1.00 42.76  ? 139 THR A CA  1 
ATOM   839   C C   . THR A 1 120 ? 34.392  -4.472  81.429  1.00 43.55  ? 139 THR A C   1 
ATOM   840   O O   . THR A 1 120 ? 34.866  -5.216  82.285  1.00 44.15  ? 139 THR A O   1 
ATOM   841   C CB  . THR A 1 120 ? 32.814  -2.539  81.519  1.00 43.32  ? 139 THR A CB  1 
ATOM   842   O OG1 . THR A 1 120 ? 33.556  -2.103  82.668  1.00 44.26  ? 139 THR A OG1 1 
ATOM   843   C CG2 . THR A 1 120 ? 31.349  -2.096  81.624  1.00 42.88  ? 139 THR A CG2 1 
ATOM   844   N N   . THR A 1 121 ? 35.124  -3.961  80.443  1.00 44.71  ? 140 THR A N   1 
ATOM   845   C CA  . THR A 1 121 ? 36.543  -4.268  80.332  1.00 45.84  ? 140 THR A CA  1 
ATOM   846   C C   . THR A 1 121 ? 37.336  -3.799  81.548  1.00 46.74  ? 140 THR A C   1 
ATOM   847   O O   . THR A 1 121 ? 38.463  -4.273  81.760  1.00 48.09  ? 140 THR A O   1 
ATOM   848   C CB  . THR A 1 121 ? 37.130  -3.593  79.090  1.00 46.26  ? 140 THR A CB  1 
ATOM   849   O OG1 . THR A 1 121 ? 36.903  -2.181  79.199  1.00 46.37  ? 140 THR A OG1 1 
ATOM   850   C CG2 . THR A 1 121 ? 36.453  -4.124  77.840  1.00 46.00  ? 140 THR A CG2 1 
ATOM   851   N N   . THR A 1 122 ? 36.797  -2.850  82.326  1.00 46.19  ? 141 THR A N   1 
ATOM   852   C CA  . THR A 1 122 ? 37.505  -2.385  83.504  1.00 48.38  ? 141 THR A CA  1 
ATOM   853   C C   . THR A 1 122 ? 37.310  -3.293  84.697  1.00 48.19  ? 141 THR A C   1 
ATOM   854   O O   . THR A 1 122 ? 38.062  -3.173  85.659  1.00 50.36  ? 141 THR A O   1 
ATOM   855   C CB  . THR A 1 122 ? 37.080  -0.935  83.846  1.00 48.83  ? 141 THR A CB  1 
ATOM   856   O OG1 . THR A 1 122 ? 35.907  -0.910  84.692  1.00 47.06  ? 141 THR A OG1 1 
ATOM   857   C CG2 . THR A 1 122 ? 36.764  -0.166  82.570  1.00 48.94  ? 141 THR A CG2 1 
ATOM   858   N N   . GLY A 1 123 ? 36.346  -4.186  84.653  1.00 45.53  ? 142 GLY A N   1 
ATOM   859   C CA  . GLY A 1 123 ? 35.956  -4.978  85.794  1.00 45.24  ? 142 GLY A CA  1 
ATOM   860   C C   . GLY A 1 123 ? 34.695  -4.487  86.473  1.00 44.47  ? 142 GLY A C   1 
ATOM   861   O O   . GLY A 1 123 ? 34.059  -5.251  87.215  1.00 44.88  ? 142 GLY A O   1 
ATOM   862   N N   . GLU A 1 124 ? 34.316  -3.236  86.230  1.00 44.63  ? 143 GLU A N   1 
ATOM   863   C CA  . GLU A 1 124 ? 33.106  -2.696  86.825  1.00 44.31  ? 143 GLU A CA  1 
ATOM   864   C C   . GLU A 1 124 ? 31.920  -3.499  86.317  1.00 42.09  ? 143 GLU A C   1 
ATOM   865   O O   . GLU A 1 124 ? 31.910  -3.985  85.182  1.00 41.04  ? 143 GLU A O   1 
ATOM   866   C CB  . GLU A 1 124 ? 32.953  -1.193  86.505  1.00 45.16  ? 143 GLU A CB  1 
ATOM   867   N N   . LEU A 1 125 ? 30.940  -3.679  87.194  1.00 41.04  ? 144 LEU A N   1 
ATOM   868   C CA  . LEU A 1 125 ? 29.664  -4.230  86.805  1.00 39.49  ? 144 LEU A CA  1 
ATOM   869   C C   . LEU A 1 125 ? 28.968  -3.298  85.820  1.00 38.28  ? 144 LEU A C   1 
ATOM   870   O O   . LEU A 1 125 ? 28.909  -2.087  86.018  1.00 39.20  ? 144 LEU A O   1 
ATOM   871   C CB  . LEU A 1 125 ? 28.820  -4.441  88.046  1.00 40.31  ? 144 LEU A CB  1 
ATOM   872   C CG  . LEU A 1 125 ? 29.230  -5.595  88.953  1.00 41.74  ? 144 LEU A CG  1 
ATOM   873   C CD1 . LEU A 1 125 ? 28.369  -5.485  90.192  1.00 42.58  ? 144 LEU A CD1 1 
ATOM   874   C CD2 . LEU A 1 125 ? 29.012  -6.940  88.262  1.00 41.09  ? 144 LEU A CD2 1 
ATOM   875   N N   . ASP A 1 126 ? 28.457  -3.897  84.742  1.00 42.79  ? 145 ASP A N   1 
ATOM   876   C CA  . ASP A 1 126 ? 27.730  -3.235  83.671  1.00 41.44  ? 145 ASP A CA  1 
ATOM   877   C C   . ASP A 1 126 ? 26.284  -3.062  84.094  1.00 41.18  ? 145 ASP A C   1 
ATOM   878   O O   . ASP A 1 126 ? 25.529  -4.036  84.134  1.00 40.12  ? 145 ASP A O   1 
ATOM   879   C CB  . ASP A 1 126 ? 27.811  -4.089  82.407  1.00 39.92  ? 145 ASP A CB  1 
ATOM   880   C CG  . ASP A 1 126 ? 27.267  -3.394  81.191  1.00 39.19  ? 145 ASP A CG  1 
ATOM   881   O OD1 . ASP A 1 126 ? 26.544  -2.398  81.369  1.00 39.31  ? 145 ASP A OD1 1 
ATOM   882   O OD2 . ASP A 1 126 ? 27.575  -3.830  80.062  1.00 38.54  ? 145 ASP A OD2 1 
ATOM   883   N N   . ARG A 1 127 ? 25.889  -1.824  84.394  1.00 45.32  ? 146 ARG A N   1 
ATOM   884   C CA  . ARG A 1 127 ? 24.511  -1.493  84.709  1.00 45.26  ? 146 ARG A CA  1 
ATOM   885   C C   . ARG A 1 127 ? 24.024  -0.327  83.856  1.00 45.56  ? 146 ARG A C   1 
ATOM   886   O O   . ARG A 1 127 ? 24.773  0.607   83.545  1.00 46.88  ? 146 ARG A O   1 
ATOM   887   C CB  . ARG A 1 127 ? 24.339  -1.133  86.197  1.00 46.51  ? 146 ARG A CB  1 
ATOM   888   C CG  . ARG A 1 127 ? 25.206  -1.913  87.118  1.00 47.15  ? 146 ARG A CG  1 
ATOM   889   C CD  . ARG A 1 127 ? 24.556  -2.131  88.467  1.00 48.04  ? 146 ARG A CD  1 
ATOM   890   N NE  . ARG A 1 127 ? 24.487  -0.886  89.225  1.00 49.60  ? 146 ARG A NE  1 
ATOM   891   C CZ  . ARG A 1 127 ? 24.927  -0.776  90.475  1.00 50.92  ? 146 ARG A CZ  1 
ATOM   892   N NH1 . ARG A 1 127 ? 25.481  -1.824  91.097  1.00 51.16  ? 146 ARG A NH1 1 
ATOM   893   N NH2 . ARG A 1 127 ? 24.800  0.391   91.127  1.00 52.85  ? 146 ARG A NH2 1 
ATOM   894   N N   . LYS A 1 128 ? 22.753  -0.395  83.491  1.00 46.34  ? 147 LYS A N   1 
ATOM   895   C CA  . LYS A 1 128 ? 22.073  0.712   82.841  1.00 47.12  ? 147 LYS A CA  1 
ATOM   896   C C   . LYS A 1 128 ? 21.559  1.703   83.891  1.00 48.89  ? 147 LYS A C   1 
ATOM   897   O O   . LYS A 1 128 ? 21.336  1.359   85.054  1.00 49.40  ? 147 LYS A O   1 
ATOM   898   C CB  . LYS A 1 128 ? 20.920  0.191   81.980  1.00 45.76  ? 147 LYS A CB  1 
ATOM   899   C CG  . LYS A 1 128 ? 20.442  1.171   80.962  1.00 47.03  ? 147 LYS A CG  1 
ATOM   900   C CD  . LYS A 1 128 ? 19.425  0.577   80.066  1.00 45.91  ? 147 LYS A CD  1 
ATOM   901   C CE  . LYS A 1 128 ? 18.065  0.588   80.716  1.00 45.74  ? 147 LYS A CE  1 
ATOM   902   N NZ  . LYS A 1 128 ? 17.075  1.129   79.696  1.00 45.81  ? 147 LYS A NZ  1 
ATOM   903   N N   . LYS A 1 129 ? 21.386  2.952   83.473  1.00 49.03  ? 148 LYS A N   1 
ATOM   904   C CA  . LYS A 1 129 ? 20.732  3.926   84.343  1.00 50.89  ? 148 LYS A CA  1 
ATOM   905   C C   . LYS A 1 129 ? 19.452  3.321   84.943  1.00 49.79  ? 148 LYS A C   1 
ATOM   906   O O   . LYS A 1 129 ? 18.661  2.664   84.256  1.00 48.42  ? 148 LYS A O   1 
ATOM   907   C CB  . LYS A 1 129 ? 20.428  5.226   83.575  1.00 52.33  ? 148 LYS A CB  1 
ATOM   908   N N   . GLY A 1 130 ? 19.245  3.571   86.239  1.00 53.48  ? 149 GLY A N   1 
ATOM   909   C CA  . GLY A 1 130 ? 18.177  2.925   86.975  1.00 52.17  ? 149 GLY A CA  1 
ATOM   910   C C   . GLY A 1 130 ? 18.606  1.724   87.786  1.00 51.96  ? 149 GLY A C   1 
ATOM   911   O O   . GLY A 1 130 ? 17.741  1.013   88.310  1.00 50.76  ? 149 GLY A O   1 
ATOM   912   N N   . GLN A 1 131 ? 19.917  1.489   87.907  1.00 47.63  ? 150 GLN A N   1 
ATOM   913   C CA  . GLN A 1 131 ? 20.469  0.442   88.752  1.00 47.94  ? 150 GLN A CA  1 
ATOM   914   C C   . GLN A 1 131 ? 20.056  -0.924  88.221  1.00 45.53  ? 150 GLN A C   1 
ATOM   915   O O   . GLN A 1 131 ? 19.725  -1.835  88.988  1.00 45.04  ? 150 GLN A O   1 
ATOM   916   C CB  . GLN A 1 131 ? 20.031  0.592   90.208  1.00 49.53  ? 150 GLN A CB  1 
ATOM   917   C CG  . GLN A 1 131 ? 19.941  1.966   90.773  1.00 51.79  ? 150 GLN A CG  1 
ATOM   918   C CD  . GLN A 1 131 ? 18.634  2.153   91.585  1.00 52.07  ? 150 GLN A CD  1 
ATOM   919   O OE1 . GLN A 1 131 ? 18.475  1.587   92.685  1.00 51.25  ? 150 GLN A OE1 1 
ATOM   920   N NE2 . GLN A 1 131 ? 17.698  2.956   91.052  1.00 52.56  ? 150 GLN A NE2 1 
ATOM   921   N N   . LEU A 1 132 ? 20.006  -1.045  86.891  1.00 44.08  ? 151 LEU A N   1 
ATOM   922   C CA  . LEU A 1 132 ? 19.613  -2.280  86.222  1.00 41.09  ? 151 LEU A CA  1 
ATOM   923   C C   . LEU A 1 132 ? 20.870  -2.945  85.713  1.00 40.56  ? 151 LEU A C   1 
ATOM   924   O O   . LEU A 1 132 ? 21.483  -2.475  84.743  1.00 41.13  ? 151 LEU A O   1 
ATOM   925   C CB  . LEU A 1 132 ? 18.683  -2.039  85.049  1.00 39.84  ? 151 LEU A CB  1 
ATOM   926   C CG  . LEU A 1 132 ? 17.239  -1.825  85.454  1.00 37.51  ? 151 LEU A CG  1 
ATOM   927   C CD1 . LEU A 1 132 ? 16.517  -1.172  84.279  1.00 36.99  ? 151 LEU A CD1 1 
ATOM   928   C CD2 . LEU A 1 132 ? 16.665  -3.150  85.866  1.00 37.38  ? 151 LEU A CD2 1 
ATOM   929   N N   . MET A 1 133 ? 21.240  -4.054  86.347  1.00 36.49  ? 152 MET A N   1 
ATOM   930   C CA  . MET A 1 133 ? 22.273  -4.914  85.789  1.00 36.52  ? 152 MET A CA  1 
ATOM   931   C C   . MET A 1 133 ? 21.875  -5.408  84.405  1.00 34.01  ? 152 MET A C   1 
ATOM   932   O O   . MET A 1 133 ? 20.698  -5.636  84.114  1.00 31.82  ? 152 MET A O   1 
ATOM   933   C CB  . MET A 1 133 ? 22.536  -6.053  86.754  1.00 38.03  ? 152 MET A CB  1 
ATOM   934   C CG  . MET A 1 133 ? 23.853  -5.860  87.572  1.00 41.21  ? 152 MET A CG  1 
ATOM   935   S SD  . MET A 1 133 ? 24.254  -7.221  88.682  1.00 42.02  ? 152 MET A SD  1 
ATOM   936   C CE  . MET A 1 133 ? 22.852  -7.293  89.757  1.00 41.85  ? 152 MET A CE  1 
ATOM   937   N N   . ARG A 1 134 ? 22.861  -5.525  83.526  1.00 36.28  ? 153 ARG A N   1 
ATOM   938   C CA  . ARG A 1 134 ? 22.657  -6.056  82.193  1.00 33.60  ? 153 ARG A CA  1 
ATOM   939   C C   . ARG A 1 134 ? 23.238  -7.463  82.132  1.00 33.23  ? 153 ARG A C   1 
ATOM   940   O O   . ARG A 1 134 ? 24.288  -7.752  82.709  1.00 35.46  ? 153 ARG A O   1 
ATOM   941   C CB  . ARG A 1 134 ? 23.276  -5.148  81.123  1.00 34.07  ? 153 ARG A CB  1 
ATOM   942   C CG  . ARG A 1 134 ? 22.705  -3.687  81.160  1.00 35.26  ? 153 ARG A CG  1 
ATOM   943   C CD  . ARG A 1 134 ? 22.838  -2.869  79.850  1.00 35.27  ? 153 ARG A CD  1 
ATOM   944   N NE  . ARG A 1 134 ? 24.240  -2.677  79.497  1.00 36.14  ? 153 ARG A NE  1 
ATOM   945   C CZ  . ARG A 1 134 ? 24.676  -2.315  78.302  1.00 36.30  ? 153 ARG A CZ  1 
ATOM   946   N NH1 . ARG A 1 134 ? 23.839  -1.952  77.346  1.00 35.61  ? 153 ARG A NH1 1 
ATOM   947   N NH2 . ARG A 1 134 ? 25.984  -2.331  78.055  1.00 37.10  ? 153 ARG A NH2 1 
ATOM   948   N N   . TYR A 1 135 ? 22.523  -8.339  81.440  1.00 32.67  ? 154 TYR A N   1 
ATOM   949   C CA  . TYR A 1 135 ? 22.860  -9.736  81.427  1.00 32.52  ? 154 TYR A CA  1 
ATOM   950   C C   . TYR A 1 135 ? 24.002  -10.020 80.475  1.00 32.52  ? 154 TYR A C   1 
ATOM   951   O O   . TYR A 1 135 ? 24.129  -9.399  79.424  1.00 32.13  ? 154 TYR A O   1 
ATOM   952   C CB  . TYR A 1 135 ? 21.672  -10.548 80.990  1.00 30.15  ? 154 TYR A CB  1 
ATOM   953   C CG  . TYR A 1 135 ? 20.491  -10.536 81.886  1.00 29.70  ? 154 TYR A CG  1 
ATOM   954   C CD1 . TYR A 1 135 ? 20.602  -10.684 83.250  1.00 31.57  ? 154 TYR A CD1 1 
ATOM   955   C CD2 . TYR A 1 135 ? 19.243  -10.459 81.355  1.00 27.86  ? 154 TYR A CD2 1 
ATOM   956   C CE1 . TYR A 1 135 ? 19.461  -10.715 84.055  1.00 31.27  ? 154 TYR A CE1 1 
ATOM   957   C CE2 . TYR A 1 135 ? 18.141  -10.481 82.136  1.00 27.38  ? 154 TYR A CE2 1 
ATOM   958   C CZ  . TYR A 1 135 ? 18.228  -10.617 83.465  1.00 28.85  ? 154 TYR A CZ  1 
ATOM   959   O OH  . TYR A 1 135 ? 17.042  -10.659 84.157  1.00 28.84  ? 154 TYR A OH  1 
ATOM   960   N N   . ASP A 1 136 ? 24.817  -11.005 80.847  1.00 35.55  ? 155 ASP A N   1 
ATOM   961   C CA  . ASP A 1 136 ? 25.859  -11.564 79.995  1.00 35.48  ? 155 ASP A CA  1 
ATOM   962   C C   . ASP A 1 136 ? 25.252  -12.711 79.220  1.00 33.65  ? 155 ASP A C   1 
ATOM   963   O O   . ASP A 1 136 ? 25.349  -13.875 79.629  1.00 34.61  ? 155 ASP A O   1 
ATOM   964   C CB  . ASP A 1 136 ? 27.037  -12.032 80.824  1.00 37.97  ? 155 ASP A CB  1 
ATOM   965   C CG  . ASP A 1 136 ? 28.228  -12.426 79.969  1.00 38.70  ? 155 ASP A CG  1 
ATOM   966   O OD1 . ASP A 1 136 ? 28.073  -12.576 78.738  1.00 37.19  ? 155 ASP A OD1 1 
ATOM   967   O OD2 . ASP A 1 136 ? 29.333  -12.528 80.526  1.00 41.20  ? 155 ASP A OD2 1 
ATOM   968   N N   . LEU A 1 137 ? 24.619  -12.400 78.085  1.00 36.06  ? 156 LEU A N   1 
ATOM   969   C CA  . LEU A 1 137 ? 23.964  -13.448 77.317  1.00 34.94  ? 156 LEU A CA  1 
ATOM   970   C C   . LEU A 1 137 ? 24.930  -14.519 76.835  1.00 36.04  ? 156 LEU A C   1 
ATOM   971   O O   . LEU A 1 137 ? 24.481  -15.534 76.305  1.00 35.61  ? 156 LEU A O   1 
ATOM   972   C CB  . LEU A 1 137 ? 23.262  -12.890 76.076  1.00 34.35  ? 156 LEU A CB  1 
ATOM   973   C CG  . LEU A 1 137 ? 22.247  -11.767 76.139  1.00 34.19  ? 156 LEU A CG  1 
ATOM   974   C CD1 . LEU A 1 137 ? 21.685  -11.688 74.731  1.00 33.86  ? 156 LEU A CD1 1 
ATOM   975   C CD2 . LEU A 1 137 ? 21.171  -12.084 77.072  1.00 33.79  ? 156 LEU A CD2 1 
ATOM   976   N N   . SER A 1 138 ? 26.228  -14.304 76.926  1.00 34.38  ? 157 SER A N   1 
ATOM   977   C CA  . SER A 1 138 ? 27.147  -15.330 76.446  1.00 35.64  ? 157 SER A CA  1 
ATOM   978   C C   . SER A 1 138 ? 27.390  -16.408 77.470  1.00 36.49  ? 157 SER A C   1 
ATOM   979   O O   . SER A 1 138 ? 28.259  -17.239 77.235  1.00 38.15  ? 157 SER A O   1 
ATOM   980   C CB  . SER A 1 138 ? 28.504  -14.728 76.066  1.00 37.75  ? 157 SER A CB  1 
ATOM   981   O OG  . SER A 1 138 ? 29.264  -14.487 77.248  1.00 39.15  ? 157 SER A OG  1 
ATOM   982   N N   . ASN A 1 139 ? 26.675  -16.401 78.591  1.00 34.29  ? 158 ASN A N   1 
ATOM   983   C CA  . ASN A 1 139 ? 26.978  -17.251 79.733  1.00 35.66  ? 158 ASN A CA  1 
ATOM   984   C C   . ASN A 1 139 ? 25.954  -18.366 79.812  1.00 34.84  ? 158 ASN A C   1 
ATOM   985   O O   . ASN A 1 139 ? 24.776  -18.098 80.062  1.00 33.61  ? 158 ASN A O   1 
ATOM   986   C CB  . ASN A 1 139 ? 26.967  -16.440 81.034  1.00 37.03  ? 158 ASN A CB  1 
ATOM   987   C CG  . ASN A 1 139 ? 27.228  -17.294 82.271  1.00 39.13  ? 158 ASN A CG  1 
ATOM   988   O OD1 . ASN A 1 139 ? 26.516  -18.267 82.540  1.00 38.95  ? 158 ASN A OD1 1 
ATOM   989   N ND2 . ASN A 1 139 ? 28.230  -16.889 83.058  1.00 41.75  ? 158 ASN A ND2 1 
ATOM   990   N N   . ALA A 1 140 ? 26.412  -19.616 79.680  1.00 36.46  ? 159 ALA A N   1 
ATOM   991   C CA  . ALA A 1 140 ? 25.477  -20.709 79.385  1.00 35.45  ? 159 ALA A CA  1 
ATOM   992   C C   . ALA A 1 140 ? 24.584  -21.041 80.577  1.00 35.95  ? 159 ALA A C   1 
ATOM   993   O O   . ALA A 1 140 ? 23.386  -21.334 80.400  1.00 34.98  ? 159 ALA A O   1 
ATOM   994   C CB  . ALA A 1 140 ? 26.253  -21.946 78.937  1.00 36.91  ? 159 ALA A CB  1 
ATOM   995   N N   . GLU A 1 141 ? 25.165  -21.039 81.789  1.00 34.86  ? 160 GLU A N   1 
ATOM   996   C CA  . GLU A 1 141 ? 24.379  -21.207 83.006  1.00 35.84  ? 160 GLU A CA  1 
ATOM   997   C C   . GLU A 1 141 ? 23.256  -20.182 83.048  1.00 34.16  ? 160 GLU A C   1 
ATOM   998   O O   . GLU A 1 141 ? 22.077  -20.538 83.231  1.00 33.46  ? 160 GLU A O   1 
ATOM   999   C CB  . GLU A 1 141 ? 25.283  -21.085 84.245  1.00 39.30  ? 160 GLU A CB  1 
ATOM   1000  C CG  . GLU A 1 141 ? 26.241  -22.240 84.463  1.00 42.57  ? 160 GLU A CG  1 
ATOM   1001  C CD  . GLU A 1 141 ? 27.146  -22.091 85.715  1.00 46.62  ? 160 GLU A CD  1 
ATOM   1002  O OE1 . GLU A 1 141 ? 27.012  -21.113 86.504  1.00 47.61  ? 160 GLU A OE1 1 
ATOM   1003  O OE2 . GLU A 1 141 ? 28.019  -22.972 85.905  1.00 49.02  ? 160 GLU A OE2 1 
ATOM   1004  N N   . PHE A 1 142 ? 23.608  -18.895 82.872  1.00 36.35  ? 161 PHE A N   1 
ATOM   1005  C CA  . PHE A 1 142 ? 22.599  -17.829 82.932  1.00 35.01  ? 161 PHE A CA  1 
ATOM   1006  C C   . PHE A 1 142 ? 21.519  -18.017 81.859  1.00 32.38  ? 161 PHE A C   1 
ATOM   1007  O O   . PHE A 1 142 ? 20.328  -17.814 82.119  1.00 31.80  ? 161 PHE A O   1 
ATOM   1008  C CB  . PHE A 1 142 ? 23.233  -16.432 82.757  1.00 34.82  ? 161 PHE A CB  1 
ATOM   1009  C CG  . PHE A 1 142 ? 22.270  -15.432 82.155  1.00 32.28  ? 161 PHE A CG  1 
ATOM   1010  C CD1 . PHE A 1 142 ? 21.361  -14.785 82.964  1.00 32.65  ? 161 PHE A CD1 1 
ATOM   1011  C CD2 . PHE A 1 142 ? 22.197  -15.232 80.779  1.00 30.73  ? 161 PHE A CD2 1 
ATOM   1012  C CE1 . PHE A 1 142 ? 20.438  -13.922 82.443  1.00 30.69  ? 161 PHE A CE1 1 
ATOM   1013  C CE2 . PHE A 1 142 ? 21.250  -14.389 80.230  1.00 28.96  ? 161 PHE A CE2 1 
ATOM   1014  C CZ  . PHE A 1 142 ? 20.375  -13.716 81.064  1.00 28.85  ? 161 PHE A CZ  1 
ATOM   1015  N N   . ARG A 1 143 ? 21.921  -18.373 80.633  1.00 34.28  ? 162 ARG A N   1 
ATOM   1016  C CA  . ARG A 1 143 ? 20.922  -18.635 79.593  1.00 32.58  ? 162 ARG A CA  1 
ATOM   1017  C C   . ARG A 1 143 ? 19.974  -19.745 80.020  1.00 32.92  ? 162 ARG A C   1 
ATOM   1018  O O   . ARG A 1 143 ? 18.757  -19.656 79.834  1.00 31.64  ? 162 ARG A O   1 
ATOM   1019  C CB  . ARG A 1 143 ? 21.597  -19.005 78.271  1.00 32.05  ? 162 ARG A CB  1 
ATOM   1020  C CG  . ARG A 1 143 ? 22.323  -17.835 77.610  1.00 32.08  ? 162 ARG A CG  1 
ATOM   1021  C CD  . ARG A 1 143 ? 22.529  -18.082 76.134  1.00 32.06  ? 162 ARG A CD  1 
ATOM   1022  N NE  . ARG A 1 143 ? 23.296  -19.297 75.898  1.00 33.45  ? 162 ARG A NE  1 
ATOM   1023  C CZ  . ARG A 1 143 ? 24.609  -19.318 75.736  1.00 34.78  ? 162 ARG A CZ  1 
ATOM   1024  N NH1 . ARG A 1 143 ? 25.321  -18.216 75.802  1.00 35.85  ? 162 ARG A NH1 1 
ATOM   1025  N NH2 . ARG A 1 143 ? 25.222  -20.480 75.523  1.00 36.94  ? 162 ARG A NH2 1 
ATOM   1026  N N   . ASN A 1 144 ? 20.520  -20.807 80.607  1.00 31.11  ? 163 ASN A N   1 
ATOM   1027  C CA  . ASN A 1 144 ? 19.663  -21.877 81.086  1.00 31.80  ? 163 ASN A CA  1 
ATOM   1028  C C   . ASN A 1 144 ? 18.686  -21.353 82.140  1.00 32.10  ? 163 ASN A C   1 
ATOM   1029  O O   . ASN A 1 144 ? 17.476  -21.584 82.060  1.00 31.58  ? 163 ASN A O   1 
ATOM   1030  C CB  . ASN A 1 144 ? 20.551  -22.995 81.627  1.00 34.13  ? 163 ASN A CB  1 
ATOM   1031  C CG  . ASN A 1 144 ? 19.766  -24.080 82.237  1.00 35.81  ? 163 ASN A CG  1 
ATOM   1032  O OD1 . ASN A 1 144 ? 18.905  -24.659 81.584  1.00 35.24  ? 163 ASN A OD1 1 
ATOM   1033  N ND2 . ASN A 1 144 ? 20.034  -24.372 83.490  1.00 38.42  ? 163 ASN A ND2 1 
ATOM   1034  N N   . TRP A 1 145 ? 19.202  -20.622 83.119  1.00 30.30  ? 164 TRP A N   1 
ATOM   1035  C CA  . TRP A 1 145 ? 18.353  -20.049 84.151  1.00 30.90  ? 164 TRP A CA  1 
ATOM   1036  C C   . TRP A 1 145 ? 17.303  -19.144 83.546  1.00 28.60  ? 164 TRP A C   1 
ATOM   1037  O O   . TRP A 1 145 ? 16.126  -19.227 83.911  1.00 28.72  ? 164 TRP A O   1 
ATOM   1038  C CB  . TRP A 1 145 ? 19.208  -19.285 85.168  1.00 33.20  ? 164 TRP A CB  1 
ATOM   1039  C CG  . TRP A 1 145 ? 18.386  -18.496 86.067  1.00 33.88  ? 164 TRP A CG  1 
ATOM   1040  C CD1 . TRP A 1 145 ? 17.705  -18.935 87.154  1.00 36.17  ? 164 TRP A CD1 1 
ATOM   1041  C CD2 . TRP A 1 145 ? 18.117  -17.089 85.950  1.00 32.34  ? 164 TRP A CD2 1 
ATOM   1042  N NE1 . TRP A 1 145 ? 17.011  -17.896 87.721  1.00 36.24  ? 164 TRP A NE1 1 
ATOM   1043  C CE2 . TRP A 1 145 ? 17.264  -16.743 87.014  1.00 33.93  ? 164 TRP A CE2 1 
ATOM   1044  C CE3 . TRP A 1 145 ? 18.530  -16.096 85.060  1.00 30.75  ? 164 TRP A CE3 1 
ATOM   1045  C CZ2 . TRP A 1 145 ? 16.813  -15.434 87.217  1.00 33.13  ? 164 TRP A CZ2 1 
ATOM   1046  C CZ3 . TRP A 1 145 ? 18.049  -14.799 85.235  1.00 29.98  ? 164 TRP A CZ3 1 
ATOM   1047  C CH2 . TRP A 1 145 ? 17.199  -14.486 86.304  1.00 31.19  ? 164 TRP A CH2 1 
ATOM   1048  N N   . TRP A 1 146 ? 17.690  -18.271 82.614  1.00 33.54  ? 165 TRP A N   1 
ATOM   1049  C CA  . TRP A 1 146 ? 16.733  -17.273 82.103  1.00 31.58  ? 165 TRP A CA  1 
ATOM   1050  C C   . TRP A 1 146 ? 15.586  -17.946 81.358  1.00 30.56  ? 165 TRP A C   1 
ATOM   1051  O O   . TRP A 1 146 ? 14.415  -17.653 81.609  1.00 30.20  ? 165 TRP A O   1 
ATOM   1052  C CB  . TRP A 1 146 ? 17.459  -16.262 81.208  1.00 30.61  ? 165 TRP A CB  1 
ATOM   1053  C CG  . TRP A 1 146 ? 16.672  -15.113 80.693  1.00 29.03  ? 165 TRP A CG  1 
ATOM   1054  C CD1 . TRP A 1 146 ? 16.628  -13.850 81.208  1.00 28.89  ? 165 TRP A CD1 1 
ATOM   1055  C CD2 . TRP A 1 146 ? 15.837  -15.097 79.529  1.00 27.59  ? 165 TRP A CD2 1 
ATOM   1056  N NE1 . TRP A 1 146 ? 15.817  -13.050 80.437  1.00 27.70  ? 165 TRP A NE1 1 
ATOM   1057  C CE2 . TRP A 1 146 ? 15.327  -13.786 79.397  1.00 26.92  ? 165 TRP A CE2 1 
ATOM   1058  C CE3 . TRP A 1 146 ? 15.479  -16.054 78.588  1.00 27.52  ? 165 TRP A CE3 1 
ATOM   1059  C CZ2 . TRP A 1 146 ? 14.459  -13.427 78.376  1.00 26.55  ? 165 TRP A CZ2 1 
ATOM   1060  C CZ3 . TRP A 1 146 ? 14.633  -15.703 77.572  1.00 26.69  ? 165 TRP A CZ3 1 
ATOM   1061  C CH2 . TRP A 1 146 ? 14.123  -14.406 77.470  1.00 26.30  ? 165 TRP A CH2 1 
ATOM   1062  N N   . THR A 1 147 ? 15.908  -18.914 80.488  1.00 29.28  ? 166 THR A N   1 
ATOM   1063  C CA  . THR A 1 147 ? 14.872  -19.668 79.761  1.00 29.06  ? 166 THR A CA  1 
ATOM   1064  C C   . THR A 1 147 ? 13.986  -20.497 80.693  1.00 30.51  ? 166 THR A C   1 
ATOM   1065  O O   . THR A 1 147 ? 12.820  -20.734 80.379  1.00 30.46  ? 166 THR A O   1 
ATOM   1066  C CB  . THR A 1 147 ? 15.536  -20.570 78.728  1.00 29.31  ? 166 THR A CB  1 
ATOM   1067  O OG1 . THR A 1 147 ? 16.433  -21.472 79.417  1.00 30.96  ? 166 THR A OG1 1 
ATOM   1068  C CG2 . THR A 1 147 ? 16.296  -19.757 77.694  1.00 28.38  ? 166 THR A CG2 1 
ATOM   1069  N N   . ASN A 1 148 ? 14.503  -20.912 81.859  1.00 26.50  ? 167 ASN A N   1 
ATOM   1070  C CA  . ASN A 1 148 ? 13.660  -21.628 82.810  1.00 28.71  ? 167 ASN A CA  1 
ATOM   1071  C C   . ASN A 1 148 ? 12.620  -20.733 83.457  1.00 28.46  ? 167 ASN A C   1 
ATOM   1072  O O   . ASN A 1 148 ? 11.507  -21.180 83.753  1.00 29.45  ? 167 ASN A O   1 
ATOM   1073  C CB  . ASN A 1 148 ? 14.541  -22.257 83.871  1.00 31.66  ? 167 ASN A CB  1 
ATOM   1074  C CG  . ASN A 1 148 ? 15.164  -23.563 83.414  1.00 33.13  ? 167 ASN A CG  1 
ATOM   1075  O OD1 . ASN A 1 148 ? 14.780  -24.130 82.385  1.00 32.17  ? 167 ASN A OD1 1 
ATOM   1076  N ND2 . ASN A 1 148 ? 16.155  -24.020 84.146  1.00 35.57  ? 167 ASN A ND2 1 
ATOM   1077  N N   . VAL A 1 149 ? 12.959  -19.460 83.674  1.00 30.94  ? 168 VAL A N   1 
ATOM   1078  C CA  . VAL A 1 149 ? 11.982  -18.500 84.178  1.00 30.47  ? 168 VAL A CA  1 
ATOM   1079  C C   . VAL A 1 149 ? 10.825  -18.396 83.197  1.00 28.75  ? 168 VAL A C   1 
ATOM   1080  O O   . VAL A 1 149 ? 9.654   -18.524 83.569  1.00 29.54  ? 168 VAL A O   1 
ATOM   1081  C CB  . VAL A 1 149 ? 12.656  -17.134 84.420  1.00 29.44  ? 168 VAL A CB  1 
ATOM   1082  C CG1 . VAL A 1 149 ? 11.593  -16.005 84.620  1.00 28.82  ? 168 VAL A CG1 1 
ATOM   1083  C CG2 . VAL A 1 149 ? 13.668  -17.247 85.568  1.00 31.95  ? 168 VAL A CG2 1 
ATOM   1084  N N   . ALA A 1 150 ? 11.142  -18.192 81.912  1.00 29.79  ? 169 ALA A N   1 
ATOM   1085  C CA  . ALA A 1 150 ? 10.104  -18.129 80.887  1.00 28.95  ? 169 ALA A CA  1 
ATOM   1086  C C   . ALA A 1 150 ? 9.279   -19.408 80.873  1.00 30.41  ? 169 ALA A C   1 
ATOM   1087  O O   . ALA A 1 150 ? 8.041   -19.360 80.816  1.00 30.88  ? 169 ALA A O   1 
ATOM   1088  C CB  . ALA A 1 150 ? 10.739  -17.881 79.515  1.00 28.14  ? 169 ALA A CB  1 
ATOM   1089  N N   . ALA A 1 151 ? 9.948   -20.567 80.944  1.00 27.51  ? 170 ALA A N   1 
ATOM   1090  C CA  . ALA A 1 151 ? 9.219   -21.828 80.908  1.00 28.97  ? 170 ALA A CA  1 
ATOM   1091  C C   . ALA A 1 151 ? 8.343   -21.969 82.129  1.00 30.54  ? 170 ALA A C   1 
ATOM   1092  O O   . ALA A 1 151 ? 7.238   -22.485 82.041  1.00 31.99  ? 170 ALA A O   1 
ATOM   1093  C CB  . ALA A 1 151 ? 10.184  -23.002 80.804  1.00 29.82  ? 170 ALA A CB  1 
ATOM   1094  N N   . LYS A 1 152 ? 8.795   -21.488 83.283  1.00 30.51  ? 171 LYS A N   1 
ATOM   1095  C CA  . LYS A 1 152 ? 7.916   -21.609 84.434  1.00 32.64  ? 171 LYS A CA  1 
ATOM   1096  C C   . LYS A 1 152 ? 6.600   -20.906 84.180  1.00 31.99  ? 171 LYS A C   1 
ATOM   1097  O O   . LYS A 1 152 ? 5.542   -21.367 84.626  1.00 34.18  ? 171 LYS A O   1 
ATOM   1098  C CB  . LYS A 1 152 ? 8.554   -21.060 85.683  1.00 34.17  ? 171 LYS A CB  1 
ATOM   1099  C CG  . LYS A 1 152 ? 7.714   -21.428 86.885  1.00 37.85  ? 171 LYS A CG  1 
ATOM   1100  C CD  . LYS A 1 152 ? 7.948   -20.551 88.150  1.00 40.42  ? 171 LYS A CD  1 
ATOM   1101  C CE  . LYS A 1 152 ? 9.333   -20.682 88.707  1.00 42.87  ? 171 LYS A CE  1 
ATOM   1102  N NZ  . LYS A 1 152 ? 9.238   -20.637 90.216  1.00 44.74  ? 171 LYS A NZ  1 
ATOM   1103  N N   . ALA A 1 153 ? 6.641   -19.805 83.456  1.00 31.83  ? 172 ALA A N   1 
ATOM   1104  C CA  . ALA A 1 153 ? 5.499   -18.928 83.324  1.00 31.49  ? 172 ALA A CA  1 
ATOM   1105  C C   . ALA A 1 153 ? 4.573   -19.375 82.212  1.00 31.91  ? 172 ALA A C   1 
ATOM   1106  O O   . ALA A 1 153 ? 3.344   -19.320 82.379  1.00 33.15  ? 172 ALA A O   1 
ATOM   1107  C CB  . ALA A 1 153 ? 6.001   -17.507 83.084  1.00 29.22  ? 172 ALA A CB  1 
ATOM   1108  N N   . VAL A 1 154 ? 5.129   -19.853 81.102  1.00 31.17  ? 173 VAL A N   1 
ATOM   1109  C CA  . VAL A 1 154 ? 4.264   -20.203 79.987  1.00 32.16  ? 173 VAL A CA  1 
ATOM   1110  C C   . VAL A 1 154 ? 3.913   -21.685 79.951  1.00 34.31  ? 173 VAL A C   1 
ATOM   1111  O O   . VAL A 1 154 ? 2.800   -22.041 79.543  1.00 36.10  ? 173 VAL A O   1 
ATOM   1112  C CB  . VAL A 1 154 ? 4.882   -19.773 78.644  1.00 31.36  ? 173 VAL A CB  1 
ATOM   1113  C CG1 . VAL A 1 154 ? 5.625   -18.438 78.772  1.00 28.98  ? 173 VAL A CG1 1 
ATOM   1114  C CG2 . VAL A 1 154 ? 5.778   -20.837 78.178  1.00 31.95  ? 173 VAL A CG2 1 
ATOM   1115  N N   . VAL A 1 155 ? 4.821   -22.553 80.414  1.00 31.11  ? 174 VAL A N   1 
ATOM   1116  C CA  . VAL A 1 155 ? 4.533   -23.993 80.412  1.00 33.20  ? 174 VAL A CA  1 
ATOM   1117  C C   . VAL A 1 155 ? 3.777   -24.394 81.679  1.00 35.24  ? 174 VAL A C   1 
ATOM   1118  O O   . VAL A 1 155 ? 2.671   -24.949 81.621  1.00 37.14  ? 174 VAL A O   1 
ATOM   1119  C CB  . VAL A 1 155 ? 5.836   -24.795 80.256  1.00 32.74  ? 174 VAL A CB  1 
ATOM   1120  C CG1 . VAL A 1 155 ? 5.524   -26.293 80.389  1.00 34.53  ? 174 VAL A CG1 1 
ATOM   1121  C CG2 . VAL A 1 155 ? 6.495   -24.449 78.947  1.00 30.98  ? 174 VAL A CG2 1 
ATOM   1122  N N   . ASP A 1 156 ? 4.409   -24.190 82.851  1.00 34.71  ? 175 ASP A N   1 
ATOM   1123  C CA  . ASP A 1 156 ? 3.772   -24.495 84.124  1.00 36.80  ? 175 ASP A CA  1 
ATOM   1124  C C   . ASP A 1 156 ? 2.676   -23.493 84.452  1.00 36.39  ? 175 ASP A C   1 
ATOM   1125  O O   . ASP A 1 156 ? 1.774   -23.775 85.241  1.00 38.02  ? 175 ASP A O   1 
ATOM   1126  C CB  . ASP A 1 156 ? 4.784   -24.439 85.261  1.00 38.08  ? 175 ASP A CB  1 
ATOM   1127  C CG  . ASP A 1 156 ? 6.064   -25.274 85.008  1.00 39.98  ? 175 ASP A CG  1 
ATOM   1128  O OD1 . ASP A 1 156 ? 6.041   -26.295 84.234  1.00 41.12  ? 175 ASP A OD1 1 
ATOM   1129  O OD2 . ASP A 1 156 ? 7.097   -24.868 85.651  1.00 40.28  ? 175 ASP A OD2 1 
ATOM   1130  N N   . GLY A 1 157 ? 2.779   -22.288 83.928  1.00 35.87  ? 176 GLY A N   1 
ATOM   1131  C CA  . GLY A 1 157 ? 1.766   -21.285 84.144  1.00 35.54  ? 176 GLY A CA  1 
ATOM   1132  C C   . GLY A 1 157 ? 0.725   -21.241 83.039  1.00 35.69  ? 176 GLY A C   1 
ATOM   1133  O O   . GLY A 1 157 ? 0.675   -22.072 82.119  1.00 36.52  ? 176 GLY A O   1 
ATOM   1134  N N   . THR A 1 158 ? -0.099  -20.207 83.130  1.00 32.72  ? 177 THR A N   1 
ATOM   1135  C CA  . THR A 1 158 ? -1.242  -20.007 82.262  1.00 33.34  ? 177 THR A CA  1 
ATOM   1136  C C   . THR A 1 158 ? -0.960  -19.089 81.097  1.00 31.85  ? 177 THR A C   1 
ATOM   1137  O O   . THR A 1 158 ? -1.873  -18.832 80.317  1.00 32.89  ? 177 THR A O   1 
ATOM   1138  C CB  . THR A 1 158 ? -2.387  -19.486 83.111  1.00 33.92  ? 177 THR A CB  1 
ATOM   1139  O OG1 . THR A 1 158 ? -2.553  -20.402 84.197  1.00 35.64  ? 177 THR A OG1 1 
ATOM   1140  C CG2 . THR A 1 158 ? -3.641  -19.397 82.341  1.00 35.04  ? 177 THR A CG2 1 
ATOM   1141  N N   . CYS A 1 159 ? 0.283   -18.661 80.897  1.00 34.30  ? 178 CYS A N   1 
ATOM   1142  C CA  . CYS A 1 159 ? 0.583   -17.804 79.755  1.00 32.45  ? 178 CYS A CA  1 
ATOM   1143  C C   . CYS A 1 159 ? 0.808   -18.616 78.475  1.00 33.34  ? 178 CYS A C   1 
ATOM   1144  O O   . CYS A 1 159 ? 1.203   -19.779 78.503  1.00 34.62  ? 178 CYS A O   1 
ATOM   1145  C CB  . CYS A 1 159 ? 1.820   -16.934 80.037  1.00 30.36  ? 178 CYS A CB  1 
ATOM   1146  S SG  . CYS A 1 159 ? 1.461   -15.523 81.137  1.00 29.75  ? 178 CYS A SG  1 
ATOM   1147  N N   . ASP A 1 160 ? 0.590   -17.947 77.336  1.00 30.34  ? 179 ASP A N   1 
ATOM   1148  C CA  . ASP A 1 160 ? 0.683   -18.549 76.013  1.00 31.15  ? 179 ASP A CA  1 
ATOM   1149  C C   . ASP A 1 160 ? 1.952   -18.193 75.261  1.00 29.24  ? 179 ASP A C   1 
ATOM   1150  O O   . ASP A 1 160 ? 2.119   -18.616 74.104  1.00 30.18  ? 179 ASP A O   1 
ATOM   1151  C CB  . ASP A 1 160 ? -0.510  -18.116 75.174  1.00 33.33  ? 179 ASP A CB  1 
ATOM   1152  C CG  . ASP A 1 160 ? -1.795  -18.517 75.784  1.00 35.24  ? 179 ASP A CG  1 
ATOM   1153  O OD1 . ASP A 1 160 ? -2.112  -19.749 75.728  1.00 37.68  ? 179 ASP A OD1 1 
ATOM   1154  O OD2 . ASP A 1 160 ? -2.469  -17.624 76.335  1.00 34.93  ? 179 ASP A OD2 1 
ATOM   1155  N N   . GLY A 1 161 ? 2.826   -17.402 75.865  1.00 31.80  ? 180 GLY A N   1 
ATOM   1156  C CA  . GLY A 1 161 ? 4.058   -17.022 75.202  1.00 29.98  ? 180 GLY A CA  1 
ATOM   1157  C C   . GLY A 1 161 ? 4.837   -16.095 76.087  1.00 28.11  ? 180 GLY A C   1 
ATOM   1158  O O   . GLY A 1 161 ? 4.416   -15.764 77.200  1.00 28.27  ? 180 GLY A O   1 
ATOM   1159  N N   . VAL A 1 162 ? 5.970   -15.655 75.547  1.00 29.72  ? 181 VAL A N   1 
ATOM   1160  C CA  . VAL A 1 162 ? 6.886   -14.755 76.223  1.00 28.65  ? 181 VAL A CA  1 
ATOM   1161  C C   . VAL A 1 162 ? 7.265   -13.622 75.278  1.00 28.62  ? 181 VAL A C   1 
ATOM   1162  O O   . VAL A 1 162 ? 7.529   -13.876 74.094  1.00 29.28  ? 181 VAL A O   1 
ATOM   1163  C CB  . VAL A 1 162 ? 8.152   -15.496 76.667  1.00 27.91  ? 181 VAL A CB  1 
ATOM   1164  C CG1 . VAL A 1 162 ? 8.839   -16.135 75.470  1.00 28.25  ? 181 VAL A CG1 1 
ATOM   1165  C CG2 . VAL A 1 162 ? 9.066   -14.517 77.343  1.00 27.42  ? 181 VAL A CG2 1 
ATOM   1166  N N   . PHE A 1 163 ? 7.342   -12.362 75.835  1.00 27.73  ? 182 PHE A N   1 
ATOM   1167  C CA  . PHE A 1 163 ? 7.784   -11.152 75.126  1.00 28.14  ? 182 PHE A CA  1 
ATOM   1168  C C   . PHE A 1 163 ? 9.241   -10.853 75.473  1.00 27.57  ? 182 PHE A C   1 
ATOM   1169  O O   . PHE A 1 163 ? 9.562   -10.504 76.615  1.00 27.49  ? 182 PHE A O   1 
ATOM   1170  C CB  . PHE A 1 163 ? 6.897   -9.962  75.496  1.00 29.11  ? 182 PHE A CB  1 
ATOM   1171  C CG  . PHE A 1 163 ? 7.155   -8.729  74.680  1.00 30.46  ? 182 PHE A CG  1 
ATOM   1172  C CD1 . PHE A 1 163 ? 8.075   -7.770  75.107  1.00 30.67  ? 182 PHE A CD1 1 
ATOM   1173  C CD2 . PHE A 1 163 ? 6.494   -8.509  73.511  1.00 32.23  ? 182 PHE A CD2 1 
ATOM   1174  C CE1 . PHE A 1 163 ? 8.341   -6.617  74.365  1.00 32.34  ? 182 PHE A CE1 1 
ATOM   1175  C CE2 . PHE A 1 163 ? 6.742   -7.352  72.776  1.00 34.15  ? 182 PHE A CE2 1 
ATOM   1176  C CZ  . PHE A 1 163 ? 7.676   -6.412  73.202  1.00 34.05  ? 182 PHE A CZ  1 
ATOM   1177  N N   . MET A 1 164 ? 10.120  -10.971 74.485  1.00 28.47  ? 183 MET A N   1 
ATOM   1178  C CA  . MET A 1 164 ? 11.559  -10.870 74.683  1.00 28.30  ? 183 MET A CA  1 
ATOM   1179  C C   . MET A 1 164 ? 12.015  -9.501  74.222  1.00 28.92  ? 183 MET A C   1 
ATOM   1180  O O   . MET A 1 164 ? 12.066  -9.225  73.014  1.00 30.28  ? 183 MET A O   1 
ATOM   1181  C CB  . MET A 1 164 ? 12.291  -11.961 73.899  1.00 27.99  ? 183 MET A CB  1 
ATOM   1182  C CG  . MET A 1 164 ? 12.140  -13.391 74.478  1.00 28.10  ? 183 MET A CG  1 
ATOM   1183  S SD  . MET A 1 164 ? 12.796  -14.546 73.256  1.00 28.87  ? 183 MET A SD  1 
ATOM   1184  C CE  . MET A 1 164 ? 14.515  -14.536 73.824  1.00 28.34  ? 183 MET A CE  1 
ATOM   1185  N N   . ASP A 1 165 ? 12.332  -8.644  75.175  1.00 28.27  ? 184 ASP A N   1 
ATOM   1186  C CA  . ASP A 1 165 ? 12.548  -7.225  74.935  1.00 29.71  ? 184 ASP A CA  1 
ATOM   1187  C C   . ASP A 1 165 ? 14.033  -6.936  74.827  1.00 30.37  ? 184 ASP A C   1 
ATOM   1188  O O   . ASP A 1 165 ? 14.881  -7.743  75.239  1.00 29.86  ? 184 ASP A O   1 
ATOM   1189  C CB  . ASP A 1 165 ? 11.938  -6.413  76.073  1.00 30.17  ? 184 ASP A CB  1 
ATOM   1190  C CG  . ASP A 1 165 ? 11.600  -5.036  75.673  1.00 32.16  ? 184 ASP A CG  1 
ATOM   1191  O OD1 . ASP A 1 165 ? 12.104  -4.603  74.619  1.00 33.83  ? 184 ASP A OD1 1 
ATOM   1192  O OD2 . ASP A 1 165 ? 10.791  -4.392  76.383  1.00 32.90  ? 184 ASP A OD2 1 
ATOM   1193  N N   . ALA A 1 166 ? 14.335  -5.770  74.227  1.00 28.73  ? 185 ALA A N   1 
ATOM   1194  C CA  . ALA A 1 166 ? 15.605  -5.082  74.355  1.00 29.73  ? 185 ALA A CA  1 
ATOM   1195  C C   . ALA A 1 166 ? 16.667  -5.570  73.392  1.00 29.65  ? 185 ALA A C   1 
ATOM   1196  O O   . ALA A 1 166 ? 17.865  -5.284  73.581  1.00 30.45  ? 185 ALA A O   1 
ATOM   1197  C CB  . ALA A 1 166 ? 16.117  -5.173  75.803  1.00 29.51  ? 185 ALA A CB  1 
ATOM   1198  N N   . PHE A 1 167 ? 16.273  -6.219  72.321  1.00 30.22  ? 186 PHE A N   1 
ATOM   1199  C CA  . PHE A 1 167 ? 17.239  -6.673  71.336  1.00 30.45  ? 186 PHE A CA  1 
ATOM   1200  C C   . PHE A 1 167 ? 18.075  -5.554  70.732  1.00 32.50  ? 186 PHE A C   1 
ATOM   1201  O O   . PHE A 1 167 ? 19.289  -5.755  70.546  1.00 33.01  ? 186 PHE A O   1 
ATOM   1202  C CB  . PHE A 1 167 ? 16.513  -7.411  70.196  1.00 30.72  ? 186 PHE A CB  1 
ATOM   1203  C CG  . PHE A 1 167 ? 16.046  -8.794  70.531  1.00 29.11  ? 186 PHE A CG  1 
ATOM   1204  C CD1 . PHE A 1 167 ? 15.667  -9.135  71.788  1.00 27.84  ? 186 PHE A CD1 1 
ATOM   1205  C CD2 . PHE A 1 167 ? 15.973  -9.752  69.538  1.00 29.64  ? 186 PHE A CD2 1 
ATOM   1206  C CE1 . PHE A 1 167 ? 15.246  -10.453 72.055  1.00 26.54  ? 186 PHE A CE1 1 
ATOM   1207  C CE2 . PHE A 1 167 ? 15.532  -11.041 69.783  1.00 28.51  ? 186 PHE A CE2 1 
ATOM   1208  C CZ  . PHE A 1 167 ? 15.182  -11.401 71.022  1.00 27.06  ? 186 PHE A CZ  1 
ATOM   1209  N N   . PRO A 1 168 ? 17.509  -4.405  70.341  1.00 30.83  ? 187 PRO A N   1 
ATOM   1210  C CA  . PRO A 1 168 ? 18.383  -3.308  69.880  1.00 32.90  ? 187 PRO A CA  1 
ATOM   1211  C C   . PRO A 1 168 ? 19.407  -2.878  70.907  1.00 33.11  ? 187 PRO A C   1 
ATOM   1212  O O   . PRO A 1 168 ? 20.527  -2.504  70.538  1.00 34.55  ? 187 PRO A O   1 
ATOM   1213  C CB  . PRO A 1 168 ? 17.390  -2.163  69.560  1.00 34.88  ? 187 PRO A CB  1 
ATOM   1214  C CG  . PRO A 1 168 ? 16.088  -2.832  69.354  1.00 34.41  ? 187 PRO A CG  1 
ATOM   1215  C CD  . PRO A 1 168 ? 16.084  -4.035  70.287  1.00 31.84  ? 187 PRO A CD  1 
ATOM   1216  N N   . GLN A 1 169 ? 19.034  -2.885  72.189  1.00 34.43  ? 188 GLN A N   1 
ATOM   1217  C CA  . GLN A 1 169 ? 19.981  -2.539  73.244  1.00 34.49  ? 188 GLN A CA  1 
ATOM   1218  C C   . GLN A 1 169 ? 21.134  -3.519  73.282  1.00 33.89  ? 188 GLN A C   1 
ATOM   1219  O O   . GLN A 1 169 ? 22.288  -3.118  73.458  1.00 35.00  ? 188 GLN A O   1 
ATOM   1220  C CB  . GLN A 1 169 ? 19.287  -2.540  74.600  1.00 33.89  ? 188 GLN A CB  1 
ATOM   1221  C CG  . GLN A 1 169 ? 18.450  -1.344  74.884  1.00 35.60  ? 188 GLN A CG  1 
ATOM   1222  C CD  . GLN A 1 169 ? 17.965  -1.353  76.311  1.00 35.75  ? 188 GLN A CD  1 
ATOM   1223  O OE1 . GLN A 1 169 ? 18.675  -0.948  77.254  1.00 36.87  ? 188 GLN A OE1 1 
ATOM   1224  N NE2 . GLN A 1 169 ? 16.741  -1.819  76.489  1.00 35.32  ? 188 GLN A NE2 1 
ATOM   1225  N N   . ILE A 1 170 ? 20.839  -4.815  73.129  1.00 34.33  ? 189 ILE A N   1 
ATOM   1226  C CA  . ILE A 1 170 ? 21.889  -5.824  73.066  1.00 33.99  ? 189 ILE A CA  1 
ATOM   1227  C C   . ILE A 1 170 ? 22.817  -5.564  71.896  1.00 35.33  ? 189 ILE A C   1 
ATOM   1228  O O   . ILE A 1 170 ? 24.042  -5.674  72.030  1.00 36.22  ? 189 ILE A O   1 
ATOM   1229  C CB  . ILE A 1 170 ? 21.276  -7.230  72.964  1.00 32.35  ? 189 ILE A CB  1 
ATOM   1230  C CG1 . ILE A 1 170 ? 20.503  -7.606  74.224  1.00 31.31  ? 189 ILE A CG1 1 
ATOM   1231  C CG2 . ILE A 1 170 ? 22.364  -8.263  72.757  1.00 32.65  ? 189 ILE A CG2 1 
ATOM   1232  C CD1 . ILE A 1 170 ? 19.533  -8.759  74.013  1.00 30.07  ? 189 ILE A CD1 1 
ATOM   1233  N N   . ALA A 1 171 ? 22.255  -5.213  70.727  1.00 33.70  ? 190 ALA A N   1 
ATOM   1234  C CA  . ALA A 1 171 ? 23.011  -5.110  69.481  1.00 35.37  ? 190 ALA A CA  1 
ATOM   1235  C C   . ALA A 1 171 ? 23.743  -3.796  69.309  1.00 37.22  ? 190 ALA A C   1 
ATOM   1236  O O   . ALA A 1 171 ? 24.575  -3.672  68.396  1.00 38.94  ? 190 ALA A O   1 
ATOM   1237  C CB  . ALA A 1 171 ? 22.099  -5.252  68.269  1.00 35.87  ? 190 ALA A CB  1 
ATOM   1238  N N   . SER A 1 172 ? 23.420  -2.810  70.123  1.00 36.48  ? 191 SER A N   1 
ATOM   1239  C CA  . SER A 1 172 ? 24.016  -1.493  69.981  1.00 38.37  ? 191 SER A CA  1 
ATOM   1240  C C   . SER A 1 172 ? 25.532  -1.577  69.913  1.00 39.58  ? 191 SER A C   1 
ATOM   1241  O O   . SER A 1 172 ? 26.193  -2.123  70.810  1.00 38.52  ? 191 SER A O   1 
ATOM   1242  C CB  . SER A 1 172 ? 23.580  -0.610  71.143  1.00 38.98  ? 191 SER A CB  1 
ATOM   1243  O OG  . SER A 1 172 ? 24.263  0.613   71.100  1.00 41.49  ? 191 SER A OG  1 
ATOM   1244  N N   . GLN A 1 173 ? 26.075  -1.013  68.833  1.00 40.40  ? 192 GLN A N   1 
ATOM   1245  C CA  . GLN A 1 173 ? 27.518  -0.996  68.643  1.00 41.94  ? 192 GLN A CA  1 
ATOM   1246  C C   . GLN A 1 173 ? 28.248  -0.364  69.819  1.00 42.62  ? 192 GLN A C   1 
ATOM   1247  O O   . GLN A 1 173 ? 29.398  -0.713  70.083  1.00 43.31  ? 192 GLN A O   1 
ATOM   1248  C CB  . GLN A 1 173 ? 27.848  -0.252  67.358  1.00 44.11  ? 192 GLN A CB  1 
ATOM   1249  C CG  . GLN A 1 173 ? 27.310  -0.945  66.142  1.00 44.51  ? 192 GLN A CG  1 
ATOM   1250  C CD  . GLN A 1 173 ? 28.014  -2.244  65.891  1.00 44.25  ? 192 GLN A CD  1 
ATOM   1251  O OE1 . GLN A 1 173 ? 29.239  -2.289  65.831  1.00 45.41  ? 192 GLN A OE1 1 
ATOM   1252  N NE2 . GLN A 1 173 ? 27.251  -3.308  65.747  1.00 43.14  ? 192 GLN A NE2 1 
ATOM   1253  N N   . ALA A 1 174 ? 27.611  0.574   70.525  1.00 42.43  ? 193 ALA A N   1 
ATOM   1254  C CA  . ALA A 1 174 ? 28.273  1.247   71.641  1.00 42.80  ? 193 ALA A CA  1 
ATOM   1255  C C   . ALA A 1 174 ? 28.704  0.257   72.717  1.00 41.38  ? 193 ALA A C   1 
ATOM   1256  O O   . ALA A 1 174 ? 29.602  0.556   73.510  1.00 42.33  ? 193 ALA A O   1 
ATOM   1257  C CB  . ALA A 1 174 ? 27.349  2.319   72.212  1.00 43.32  ? 193 ALA A CB  1 
ATOM   1258  N N   . ASN A 1 175 ? 28.101  -0.923  72.750  1.00 42.13  ? 194 ASN A N   1 
ATOM   1259  C CA  . ASN A 1 175 ? 28.516  -1.937  73.700  1.00 41.14  ? 194 ASN A CA  1 
ATOM   1260  C C   . ASN A 1 175 ? 29.928  -2.412  73.417  1.00 42.23  ? 194 ASN A C   1 
ATOM   1261  O O   . ASN A 1 175 ? 30.588  -2.926  74.332  1.00 42.56  ? 194 ASN A O   1 
ATOM   1262  C CB  . ASN A 1 175 ? 27.534  -3.095  73.646  1.00 39.10  ? 194 ASN A CB  1 
ATOM   1263  C CG  . ASN A 1 175 ? 26.206  -2.733  74.217  1.00 38.25  ? 194 ASN A CG  1 
ATOM   1264  O OD1 . ASN A 1 175 ? 26.132  -2.011  75.201  1.00 38.89  ? 194 ASN A OD1 1 
ATOM   1265  N ND2 . ASN A 1 175 ? 25.139  -3.215  73.600  1.00 37.11  ? 194 ASN A ND2 1 
ATOM   1266  N N   . ARG A 1 176 ? 30.412  -2.238  72.183  1.00 42.23  ? 195 ARG A N   1 
ATOM   1267  C CA  . ARG A 1 176 ? 31.776  -2.656  71.876  1.00 43.53  ? 195 ARG A CA  1 
ATOM   1268  C C   . ARG A 1 176 ? 32.784  -1.927  72.761  1.00 45.21  ? 195 ARG A C   1 
ATOM   1269  O O   . ARG A 1 176 ? 33.735  -2.541  73.264  1.00 46.18  ? 195 ARG A O   1 
ATOM   1270  C CB  . ARG A 1 176 ? 32.074  -2.416  70.404  1.00 44.78  ? 195 ARG A CB  1 
ATOM   1271  C CG  . ARG A 1 176 ? 31.574  -3.515  69.508  1.00 43.86  ? 195 ARG A CG  1 
ATOM   1272  C CD  . ARG A 1 176 ? 31.491  -3.071  68.061  1.00 45.53  ? 195 ARG A CD  1 
ATOM   1273  N NE  . ARG A 1 176 ? 30.967  -4.160  67.246  1.00 44.99  ? 195 ARG A NE  1 
ATOM   1274  C CZ  . ARG A 1 176 ? 31.638  -5.273  66.967  1.00 45.20  ? 195 ARG A CZ  1 
ATOM   1275  N NH1 . ARG A 1 176 ? 32.903  -5.422  67.331  1.00 46.30  ? 195 ARG A NH1 1 
ATOM   1276  N NH2 . ARG A 1 176 ? 31.021  -6.260  66.312  1.00 44.48  ? 195 ARG A NH2 1 
ATOM   1277  N N   . LYS A 1 177 ? 32.587  -0.616  72.978  1.00 42.77  ? 196 LYS A N   1 
ATOM   1278  C CA  . LYS A 1 177 ? 33.516  0.136   73.828  1.00 44.67  ? 196 LYS A CA  1 
ATOM   1279  C C   . LYS A 1 177 ? 33.496  -0.398  75.261  1.00 43.45  ? 196 LYS A C   1 
ATOM   1280  O O   . LYS A 1 177 ? 34.503  -0.315  75.971  1.00 44.56  ? 196 LYS A O   1 
ATOM   1281  C CB  . LYS A 1 177 ? 33.195  1.643   73.785  1.00 47.08  ? 196 LYS A CB  1 
ATOM   1282  N N   . LEU A 1 178 ? 32.377  -0.955  75.696  1.00 43.37  ? 197 LEU A N   1 
ATOM   1283  C CA  . LEU A 1 178 ? 32.255  -1.394  77.069  1.00 43.12  ? 197 LEU A CA  1 
ATOM   1284  C C   . LEU A 1 178 ? 32.778  -2.802  77.273  1.00 42.61  ? 197 LEU A C   1 
ATOM   1285  O O   . LEU A 1 178 ? 33.414  -3.076  78.298  1.00 43.43  ? 197 LEU A O   1 
ATOM   1286  C CB  . LEU A 1 178 ? 30.793  -1.352  77.512  1.00 42.51  ? 197 LEU A CB  1 
ATOM   1287  C CG  . LEU A 1 178 ? 30.090  -0.005  77.696  1.00 43.88  ? 197 LEU A CG  1 
ATOM   1288  C CD1 . LEU A 1 178 ? 28.581  -0.236  77.858  1.00 43.00  ? 197 LEU A CD1 1 
ATOM   1289  C CD2 . LEU A 1 178 ? 30.671  0.650   78.890  1.00 45.87  ? 197 LEU A CD2 1 
ATOM   1290  N N   . TRP A 1 179 ? 32.515  -3.695  76.313  1.00 44.04  ? 198 TRP A N   1 
ATOM   1291  C CA  . TRP A 1 179 ? 32.829  -5.109  76.467  1.00 43.64  ? 198 TRP A CA  1 
ATOM   1292  C C   . TRP A 1 179 ? 34.070  -5.561  75.713  1.00 44.75  ? 198 TRP A C   1 
ATOM   1293  O O   . TRP A 1 179 ? 34.689  -6.571  76.090  1.00 45.66  ? 198 TRP A O   1 
ATOM   1294  C CB  . TRP A 1 179 ? 31.685  -5.976  75.961  1.00 41.69  ? 198 TRP A CB  1 
ATOM   1295  C CG  . TRP A 1 179 ? 30.415  -5.721  76.570  1.00 40.30  ? 198 TRP A CG  1 
ATOM   1296  C CD1 . TRP A 1 179 ? 30.184  -5.268  77.819  1.00 40.71  ? 198 TRP A CD1 1 
ATOM   1297  C CD2 . TRP A 1 179 ? 29.141  -5.909  75.962  1.00 38.66  ? 198 TRP A CD2 1 
ATOM   1298  N NE1 . TRP A 1 179 ? 28.840  -5.173  78.047  1.00 39.60  ? 198 TRP A NE1 1 
ATOM   1299  C CE2 . TRP A 1 179 ? 28.176  -5.548  76.906  1.00 38.23  ? 198 TRP A CE2 1 
ATOM   1300  C CE3 . TRP A 1 179 ? 28.724  -6.343  74.706  1.00 37.76  ? 198 TRP A CE3 1 
ATOM   1301  C CZ2 . TRP A 1 179 ? 26.821  -5.610  76.633  1.00 36.70  ? 198 TRP A CZ2 1 
ATOM   1302  C CZ3 . TRP A 1 179 ? 27.391  -6.419  74.453  1.00 36.43  ? 198 TRP A CZ3 1 
ATOM   1303  C CH2 . TRP A 1 179 ? 26.456  -6.054  75.408  1.00 35.91  ? 198 TRP A CH2 1 
ATOM   1304  N N   . GLY A 1 180 ? 34.417  -4.872  74.638  1.00 43.78  ? 199 GLY A N   1 
ATOM   1305  C CA  . GLY A 1 180 ? 35.427  -5.363  73.731  1.00 45.15  ? 199 GLY A CA  1 
ATOM   1306  C C   . GLY A 1 180 ? 34.816  -6.169  72.601  1.00 44.62  ? 199 GLY A C   1 
ATOM   1307  O O   . GLY A 1 180 ? 33.697  -6.665  72.682  1.00 42.84  ? 199 GLY A O   1 
ATOM   1308  N N   . ASP A 1 181 ? 35.579  -6.293  71.520  1.00 45.59  ? 200 ASP A N   1 
ATOM   1309  C CA  . ASP A 1 181 ? 35.050  -6.958  70.340  1.00 44.95  ? 200 ASP A CA  1 
ATOM   1310  C C   . ASP A 1 181 ? 34.729  -8.420  70.626  1.00 45.02  ? 200 ASP A C   1 
ATOM   1311  O O   . ASP A 1 181 ? 33.610  -8.871  70.357  1.00 43.24  ? 200 ASP A O   1 
ATOM   1312  C CB  . ASP A 1 181 ? 36.030  -6.804  69.187  1.00 47.86  ? 200 ASP A CB  1 
ATOM   1313  C CG  . ASP A 1 181 ? 36.102  -5.360  68.687  1.00 48.72  ? 200 ASP A CG  1 
ATOM   1314  O OD1 . ASP A 1 181 ? 35.044  -4.665  68.754  1.00 46.89  ? 200 ASP A OD1 1 
ATOM   1315  O OD2 . ASP A 1 181 ? 37.214  -4.929  68.257  1.00 51.62  ? 200 ASP A OD2 1 
ATOM   1316  N N   . GLU A 1 182 ? 35.689  -9.173  71.201  1.00 44.83  ? 201 GLU A N   1 
ATOM   1317  C CA  . GLU A 1 182 ? 35.501  -10.608 71.451  1.00 44.62  ? 201 GLU A CA  1 
ATOM   1318  C C   . GLU A 1 182 ? 34.232  -10.875 72.262  1.00 41.70  ? 201 GLU A C   1 
ATOM   1319  O O   . GLU A 1 182 ? 33.386  -11.693 71.880  1.00 40.69  ? 201 GLU A O   1 
ATOM   1320  C CB  . GLU A 1 182 ? 36.711  -11.206 72.169  1.00 47.20  ? 201 GLU A CB  1 
ATOM   1321  N N   . LYS A 1 183 ? 34.062  -10.169 73.369  1.00 43.49  ? 202 LYS A N   1 
ATOM   1322  C CA  . LYS A 1 183 ? 32.858  -10.360 74.170  1.00 41.72  ? 202 LYS A CA  1 
ATOM   1323  C C   . LYS A 1 183 ? 31.611  -9.874  73.431  1.00 39.33  ? 202 LYS A C   1 
ATOM   1324  O O   . LYS A 1 183 ? 30.538  -10.502 73.533  1.00 38.20  ? 202 LYS A O   1 
ATOM   1325  C CB  . LYS A 1 183 ? 33.051  -9.657  75.509  1.00 42.31  ? 202 LYS A CB  1 
ATOM   1326  C CG  . LYS A 1 183 ? 31.842  -9.577  76.426  1.00 41.35  ? 202 LYS A CG  1 
ATOM   1327  C CD  . LYS A 1 183 ? 31.392  -10.905 77.020  1.00 42.14  ? 202 LYS A CD  1 
ATOM   1328  C CE  . LYS A 1 183 ? 31.946  -11.113 78.403  1.00 43.39  ? 202 LYS A CE  1 
ATOM   1329  N NZ  . LYS A 1 183 ? 31.533  -12.405 78.940  1.00 43.05  ? 202 LYS A NZ  1 
ATOM   1330  N N   . PHE A 1 184 ? 31.722  -8.760  72.678  1.00 44.20  ? 203 PHE A N   1 
ATOM   1331  C CA  . PHE A 1 184 ? 30.548  -8.213  72.006  1.00 42.22  ? 203 PHE A CA  1 
ATOM   1332  C C   . PHE A 1 184 ? 29.953  -9.233  71.040  1.00 41.74  ? 203 PHE A C   1 
ATOM   1333  O O   . PHE A 1 184 ? 28.735  -9.461  71.018  1.00 40.00  ? 203 PHE A O   1 
ATOM   1334  C CB  . PHE A 1 184 ? 30.879  -6.927  71.256  1.00 42.44  ? 203 PHE A CB  1 
ATOM   1335  C CG  . PHE A 1 184 ? 29.684  -6.354  70.504  1.00 40.18  ? 203 PHE A CG  1 
ATOM   1336  C CD1 . PHE A 1 184 ? 28.720  -5.591  71.164  1.00 39.04  ? 203 PHE A CD1 1 
ATOM   1337  C CD2 . PHE A 1 184 ? 29.488  -6.625  69.146  1.00 40.57  ? 203 PHE A CD2 1 
ATOM   1338  C CE1 . PHE A 1 184 ? 27.606  -5.086  70.477  1.00 38.03  ? 203 PHE A CE1 1 
ATOM   1339  C CE2 . PHE A 1 184 ? 28.376  -6.128  68.465  1.00 39.37  ? 203 PHE A CE2 1 
ATOM   1340  C CZ  . PHE A 1 184 ? 27.436  -5.357  69.135  1.00 38.09  ? 203 PHE A CZ  1 
ATOM   1341  N N   . GLU A 1 185 ? 30.804  -9.855  70.223  1.00 43.13  ? 204 GLU A N   1 
ATOM   1342  C CA  . GLU A 1 185 ? 30.310  -10.899 69.330  1.00 42.86  ? 204 GLU A CA  1 
ATOM   1343  C C   . GLU A 1 185 ? 29.736  -12.067 70.128  1.00 42.32  ? 204 GLU A C   1 
ATOM   1344  O O   . GLU A 1 185 ? 28.656  -12.572 69.803  1.00 41.06  ? 204 GLU A O   1 
ATOM   1345  C CB  . GLU A 1 185 ? 31.404  -11.368 68.373  1.00 45.36  ? 204 GLU A CB  1 
ATOM   1346  C CG  . GLU A 1 185 ? 31.892  -10.293 67.355  1.00 46.63  ? 204 GLU A CG  1 
ATOM   1347  C CD  . GLU A 1 185 ? 30.861  -9.820  66.274  1.00 46.16  ? 204 GLU A CD  1 
ATOM   1348  O OE1 . GLU A 1 185 ? 29.709  -10.350 66.191  1.00 44.89  ? 204 GLU A OE1 1 
ATOM   1349  O OE2 . GLU A 1 185 ? 31.232  -8.892  65.480  1.00 48.01  ? 204 GLU A OE2 1 
ATOM   1350  N N   . ALA A 1 186 ? 30.404  -12.469 71.214  1.00 39.79  ? 205 ALA A N   1 
ATOM   1351  C CA  . ALA A 1 186 ? 29.933  -13.610 71.997  1.00 39.61  ? 205 ALA A CA  1 
ATOM   1352  C C   . ALA A 1 186 ? 28.535  -13.375 72.537  1.00 37.84  ? 205 ALA A C   1 
ATOM   1353  O O   . ALA A 1 186 ? 27.733  -14.305 72.635  1.00 37.35  ? 205 ALA A O   1 
ATOM   1354  C CB  . ALA A 1 186 ? 30.901  -13.891 73.147  1.00 41.42  ? 205 ALA A CB  1 
ATOM   1355  N N   . ILE A 1 187 ? 28.233  -12.140 72.918  1.00 40.03  ? 206 ILE A N   1 
ATOM   1356  C CA  . ILE A 1 187 ? 26.898  -11.809 73.407  1.00 38.17  ? 206 ILE A CA  1 
ATOM   1357  C C   . ILE A 1 187 ? 25.911  -11.832 72.249  1.00 36.43  ? 206 ILE A C   1 
ATOM   1358  O O   . ILE A 1 187 ? 24.755  -12.269 72.400  1.00 35.33  ? 206 ILE A O   1 
ATOM   1359  C CB  . ILE A 1 187 ? 26.943  -10.451 74.135  1.00 38.04  ? 206 ILE A CB  1 
ATOM   1360  C CG1 . ILE A 1 187 ? 27.556  -10.657 75.539  1.00 39.76  ? 206 ILE A CG1 1 
ATOM   1361  C CG2 . ILE A 1 187 ? 25.594  -9.876  74.266  1.00 35.87  ? 206 ILE A CG2 1 
ATOM   1362  C CD1 . ILE A 1 187 ? 27.660  -9.392  76.393  1.00 39.74  ? 206 ILE A CD1 1 
ATOM   1363  N N   . GLN A 1 188 ? 26.361  -11.405 71.070  1.00 38.45  ? 207 GLN A N   1 
ATOM   1364  C CA  . GLN A 1 188 ? 25.505  -11.476 69.898  1.00 37.12  ? 207 GLN A CA  1 
ATOM   1365  C C   . GLN A 1 188 ? 25.142  -12.935 69.603  1.00 37.79  ? 207 GLN A C   1 
ATOM   1366  O O   . GLN A 1 188 ? 23.967  -13.272 69.405  1.00 36.77  ? 207 GLN A O   1 
ATOM   1367  C CB  . GLN A 1 188 ? 26.184  -10.787 68.713  1.00 37.35  ? 207 GLN A CB  1 
ATOM   1368  C CG  . GLN A 1 188 ? 26.467  -9.298  68.952  1.00 37.16  ? 207 GLN A CG  1 
ATOM   1369  C CD  . GLN A 1 188 ? 25.295  -8.587  69.619  1.00 35.84  ? 207 GLN A CD  1 
ATOM   1370  O OE1 . GLN A 1 188 ? 24.177  -8.561  69.098  1.00 34.88  ? 207 GLN A OE1 1 
ATOM   1371  N NE2 . GLN A 1 188 ? 25.525  -8.103  70.821  1.00 36.35  ? 207 GLN A NE2 1 
ATOM   1372  N N   . GLN A 1 189 ? 26.133  -13.827 69.645  1.00 37.82  ? 208 GLN A N   1 
ATOM   1373  C CA  . GLN A 1 189 ? 25.846  -15.247 69.497  1.00 38.35  ? 208 GLN A CA  1 
ATOM   1374  C C   . GLN A 1 189 ? 24.944  -15.745 70.614  1.00 37.74  ? 208 GLN A C   1 
ATOM   1375  O O   . GLN A 1 189 ? 24.024  -16.533 70.373  1.00 37.36  ? 208 GLN A O   1 
ATOM   1376  C CB  . GLN A 1 189 ? 27.147  -16.037 69.453  1.00 40.56  ? 208 GLN A CB  1 
ATOM   1377  C CG  . GLN A 1 189 ? 26.953  -17.516 69.207  1.00 41.87  ? 208 GLN A CG  1 
ATOM   1378  C CD  . GLN A 1 189 ? 26.313  -17.816 67.853  1.00 41.98  ? 208 GLN A CD  1 
ATOM   1379  O OE1 . GLN A 1 189 ? 25.154  -18.251 67.790  1.00 40.91  ? 208 GLN A OE1 1 
ATOM   1380  N NE2 . GLN A 1 189 ? 27.063  -17.595 66.762  1.00 44.40  ? 208 GLN A NE2 1 
ATOM   1381  N N   . GLY A 1 190 ? 25.165  -15.287 71.839  1.00 37.06  ? 209 GLY A N   1 
ATOM   1382  C CA  . GLY A 1 190 ? 24.314  -15.718 72.942  1.00 36.89  ? 209 GLY A CA  1 
ATOM   1383  C C   . GLY A 1 190 ? 22.873  -15.253 72.814  1.00 34.76  ? 209 GLY A C   1 
ATOM   1384  O O   . GLY A 1 190 ? 21.953  -15.860 73.382  1.00 34.88  ? 209 GLY A O   1 
ATOM   1385  N N   . LEU A 1 191 ? 22.648  -14.151 72.100  1.00 36.29  ? 210 LEU A N   1 
ATOM   1386  C CA  . LEU A 1 191 ? 21.268  -13.776 71.787  1.00 34.20  ? 210 LEU A CA  1 
ATOM   1387  C C   . LEU A 1 191 ? 20.623  -14.823 70.864  1.00 34.17  ? 210 LEU A C   1 
ATOM   1388  O O   . LEU A 1 191 ? 19.505  -15.291 71.132  1.00 33.65  ? 210 LEU A O   1 
ATOM   1389  C CB  . LEU A 1 191 ? 21.231  -12.374 71.191  1.00 33.00  ? 210 LEU A CB  1 
ATOM   1390  C CG  . LEU A 1 191 ? 19.831  -11.900 70.826  1.00 31.02  ? 210 LEU A CG  1 
ATOM   1391  C CD1 . LEU A 1 191 ? 18.872  -11.895 71.953  1.00 30.39  ? 210 LEU A CD1 1 
ATOM   1392  C CD2 . LEU A 1 191 ? 19.936  -10.523 70.235  1.00 30.43  ? 210 LEU A CD2 1 
ATOM   1393  N N   . GLN A 1 192 ? 21.328  -15.234 69.805  1.00 33.26  ? 211 GLN A N   1 
ATOM   1394  C CA  . GLN A 1 192 ? 20.863  -16.345 68.958  1.00 33.76  ? 211 GLN A CA  1 
ATOM   1395  C C   . GLN A 1 192 ? 20.615  -17.618 69.780  1.00 34.57  ? 211 GLN A C   1 
ATOM   1396  O O   . GLN A 1 192 ? 19.579  -18.267 69.666  1.00 34.50  ? 211 GLN A O   1 
ATOM   1397  C CB  . GLN A 1 192 ? 21.887  -16.623 67.851  1.00 34.94  ? 211 GLN A CB  1 
ATOM   1398  N N   . ASP A 1 193 ? 21.548  -17.961 70.654  1.00 34.16  ? 212 ASP A N   1 
ATOM   1399  C CA  . ASP A 1 193 ? 21.406  -19.177 71.458  1.00 35.15  ? 212 ASP A CA  1 
ATOM   1400  C C   . ASP A 1 193 ? 20.214  -19.109 72.415  1.00 34.24  ? 212 ASP A C   1 
ATOM   1401  O O   . ASP A 1 193 ? 19.497  -20.111 72.600  1.00 34.72  ? 212 ASP A O   1 
ATOM   1402  C CB  . ASP A 1 193 ? 22.715  -19.437 72.214  1.00 37.13  ? 212 ASP A CB  1 
ATOM   1403  C CG  . ASP A 1 193 ? 23.899  -19.713 71.271  1.00 39.26  ? 212 ASP A CG  1 
ATOM   1404  O OD1 . ASP A 1 193 ? 23.696  -20.129 70.107  1.00 40.68  ? 212 ASP A OD1 1 
ATOM   1405  O OD2 . ASP A 1 193 ? 25.060  -19.516 71.676  1.00 40.50  ? 212 ASP A OD2 1 
ATOM   1406  N N   . ILE A 1 194 ? 19.971  -17.934 73.013  1.00 33.12  ? 213 ILE A N   1 
ATOM   1407  C CA  . ILE A 1 194 ? 18.949  -17.796 74.038  1.00 32.90  ? 213 ILE A CA  1 
ATOM   1408  C C   . ILE A 1 194 ? 17.583  -17.913 73.412  1.00 31.65  ? 213 ILE A C   1 
ATOM   1409  O O   . ILE A 1 194 ? 16.613  -18.304 74.073  1.00 31.69  ? 213 ILE A O   1 
ATOM   1410  C CB  . ILE A 1 194 ? 19.128  -16.457 74.814  1.00 32.62  ? 213 ILE A CB  1 
ATOM   1411  C CG1 . ILE A 1 194 ? 18.680  -16.681 76.276  1.00 32.89  ? 213 ILE A CG1 1 
ATOM   1412  C CG2 . ILE A 1 194 ? 18.327  -15.325 74.187  1.00 30.63  ? 213 ILE A CG2 1 
ATOM   1413  C CD1 . ILE A 1 194 ? 18.807  -15.511 77.161  1.00 32.90  ? 213 ILE A CD1 1 
ATOM   1414  N N   . ILE A 1 195 ? 17.463  -17.524 72.144  1.00 33.88  ? 214 ILE A N   1 
ATOM   1415  C CA  . ILE A 1 195 ? 16.181  -17.650 71.464  1.00 32.83  ? 214 ILE A CA  1 
ATOM   1416  C C   . ILE A 1 195 ? 15.918  -19.116 71.179  1.00 34.17  ? 214 ILE A C   1 
ATOM   1417  O O   . ILE A 1 195 ? 14.799  -19.624 71.363  1.00 34.18  ? 214 ILE A O   1 
ATOM   1418  C CB  . ILE A 1 195 ? 16.174  -16.802 70.180  1.00 31.79  ? 214 ILE A CB  1 
ATOM   1419  C CG1 . ILE A 1 195 ? 16.304  -15.312 70.532  1.00 30.39  ? 214 ILE A CG1 1 
ATOM   1420  C CG2 . ILE A 1 195 ? 14.913  -17.044 69.392  1.00 31.64  ? 214 ILE A CG2 1 
ATOM   1421  C CD1 . ILE A 1 195 ? 16.761  -14.449 69.387  1.00 30.13  ? 214 ILE A CD1 1 
ATOM   1422  N N   . GLN A 1 196 ? 16.964  -19.814 70.741  1.00 34.40  ? 215 GLN A N   1 
ATOM   1423  C CA  . GLN A 1 196 ? 16.827  -21.233 70.479  1.00 35.81  ? 215 GLN A CA  1 
ATOM   1424  C C   . GLN A 1 196 ? 16.498  -21.982 71.763  1.00 36.38  ? 215 GLN A C   1 
ATOM   1425  O O   . GLN A 1 196 ? 15.618  -22.853 71.766  1.00 36.62  ? 215 GLN A O   1 
ATOM   1426  C CB  . GLN A 1 196 ? 18.101  -21.806 69.861  1.00 37.20  ? 215 GLN A CB  1 
ATOM   1427  C CG  . GLN A 1 196 ? 17.753  -23.074 69.174  1.00 38.26  ? 215 GLN A CG  1 
ATOM   1428  C CD  . GLN A 1 196 ? 18.969  -23.806 68.661  1.00 39.58  ? 215 GLN A CD  1 
ATOM   1429  O OE1 . GLN A 1 196 ? 20.082  -23.695 69.162  1.00 40.01  ? 215 GLN A OE1 1 
ATOM   1430  N NE2 . GLN A 1 196 ? 18.709  -24.640 67.613  1.00 40.72  ? 215 GLN A NE2 1 
ATOM   1431  N N   . GLU A 1 197 ? 17.194  -21.637 72.875  1.00 34.51  ? 216 GLU A N   1 
ATOM   1432  C CA  . GLU A 1 197 ? 16.934  -22.328 74.124  1.00 34.69  ? 216 GLU A CA  1 
ATOM   1433  C C   . GLU A 1 197 ? 15.550  -21.992 74.670  1.00 33.85  ? 216 GLU A C   1 
ATOM   1434  O O   . GLU A 1 197 ? 14.921  -22.844 75.305  1.00 33.72  ? 216 GLU A O   1 
ATOM   1435  C CB  . GLU A 1 197 ? 18.016  -22.011 75.150  1.00 35.15  ? 216 GLU A CB  1 
ATOM   1436  C CG  . GLU A 1 197 ? 17.977  -23.007 76.341  1.00 35.24  ? 216 GLU A CG  1 
ATOM   1437  C CD  . GLU A 1 197 ? 19.198  -22.979 77.257  1.00 36.93  ? 216 GLU A CD  1 
ATOM   1438  O OE1 . GLU A 1 197 ? 19.148  -23.675 78.326  1.00 39.16  ? 216 GLU A OE1 1 
ATOM   1439  O OE2 . GLU A 1 197 ? 20.203  -22.302 76.924  1.00 36.83  ? 216 GLU A OE2 1 
ATOM   1440  N N   . THR A 1 198 ? 15.047  -20.776 74.414  1.00 32.54  ? 217 THR A N   1 
ATOM   1441  C CA  . THR A 1 198 ? 13.686  -20.426 74.814  1.00 31.62  ? 217 THR A CA  1 
ATOM   1442  C C   . THR A 1 198 ? 12.662  -21.318 74.119  1.00 31.84  ? 217 THR A C   1 
ATOM   1443  O O   . THR A 1 198 ? 11.689  -21.783 74.727  1.00 32.06  ? 217 THR A O   1 
ATOM   1444  C CB  . THR A 1 198 ? 13.375  -18.963 74.475  1.00 30.24  ? 217 THR A CB  1 
ATOM   1445  O OG1 . THR A 1 198 ? 14.306  -18.093 75.121  1.00 30.20  ? 217 THR A OG1 1 
ATOM   1446  C CG2 . THR A 1 198 ? 11.938  -18.639 74.887  1.00 28.85  ? 217 THR A CG2 1 
ATOM   1447  N N   . ARG A 1 199 ? 12.837  -21.502 72.814  1.00 33.39  ? 218 ARG A N   1 
ATOM   1448  C CA  . ARG A 1 199 ? 11.925  -22.345 72.051  1.00 34.02  ? 218 ARG A CA  1 
ATOM   1449  C C   . ARG A 1 199 ? 11.978  -23.781 72.547  1.00 35.15  ? 218 ARG A C   1 
ATOM   1450  O O   . ARG A 1 199 ? 10.935  -24.396 72.779  1.00 35.96  ? 218 ARG A O   1 
ATOM   1451  C CB  . ARG A 1 199 ? 12.249  -22.221 70.566  1.00 34.37  ? 218 ARG A CB  1 
ATOM   1452  C CG  . ARG A 1 199 ? 11.422  -23.103 69.728  1.00 35.24  ? 218 ARG A CG  1 
ATOM   1453  C CD  . ARG A 1 199 ? 9.931   -22.884 69.889  1.00 34.48  ? 218 ARG A CD  1 
ATOM   1454  N NE  . ARG A 1 199 ? 9.516   -21.631 69.287  1.00 32.86  ? 218 ARG A NE  1 
ATOM   1455  C CZ  . ARG A 1 199 ? 8.338   -21.043 69.463  1.00 31.05  ? 218 ARG A CZ  1 
ATOM   1456  N NH1 . ARG A 1 199 ? 7.377   -21.598 70.194  1.00 30.87  ? 218 ARG A NH1 1 
ATOM   1457  N NH2 . ARG A 1 199 ? 8.130   -19.846 68.912  1.00 29.24  ? 218 ARG A NH2 1 
ATOM   1458  N N   . GLN A 1 200 ? 13.172  -24.276 72.847  1.00 32.40  ? 219 GLN A N   1 
ATOM   1459  C CA  . GLN A 1 200 ? 13.292  -25.616 73.444  1.00 33.07  ? 219 GLN A CA  1 
ATOM   1460  C C   . GLN A 1 200 ? 12.577  -25.711 74.785  1.00 32.55  ? 219 GLN A C   1 
ATOM   1461  O O   . GLN A 1 200 ? 12.006  -26.747 75.120  1.00 33.24  ? 219 GLN A O   1 
ATOM   1462  C CB  . GLN A 1 200 ? 14.754  -26.005 73.629  1.00 33.71  ? 219 GLN A CB  1 
ATOM   1463  C CG  . GLN A 1 200 ? 15.483  -26.081 72.345  1.00 35.10  ? 219 GLN A CG  1 
ATOM   1464  C CD  . GLN A 1 200 ? 16.956  -26.169 72.549  1.00 36.06  ? 219 GLN A CD  1 
ATOM   1465  O OE1 . GLN A 1 200 ? 17.455  -25.962 73.655  1.00 35.55  ? 219 GLN A OE1 1 
ATOM   1466  N NE2 . GLN A 1 200 ? 17.674  -26.495 71.498  1.00 37.82  ? 219 GLN A NE2 1 
ATOM   1467  N N   . LYS A 1 201 ? 12.598  -24.632 75.570  1.00 34.62  ? 220 LYS A N   1 
ATOM   1468  C CA  . LYS A 1 201 ? 12.084  -24.734 76.933  1.00 33.60  ? 220 LYS A CA  1 
ATOM   1469  C C   . LYS A 1 201 ? 10.574  -24.547 77.008  1.00 32.32  ? 220 LYS A C   1 
ATOM   1470  O O   . LYS A 1 201 ? 9.940   -25.038 77.939  1.00 31.22  ? 220 LYS A O   1 
ATOM   1471  C CB  . LYS A 1 201 ? 12.772  -23.705 77.850  1.00 33.52  ? 220 LYS A CB  1 
ATOM   1472  C CG  . LYS A 1 201 ? 14.261  -23.951 77.986  1.00 35.12  ? 220 LYS A CG  1 
ATOM   1473  C CD  . LYS A 1 201 ? 14.554  -24.796 79.206  1.00 34.86  ? 220 LYS A CD  1 
ATOM   1474  C CE  . LYS A 1 201 ? 16.034  -25.161 79.244  1.00 36.16  ? 220 LYS A CE  1 
ATOM   1475  N NZ  . LYS A 1 201 ? 16.787  -24.161 80.092  1.00 35.73  ? 220 LYS A NZ  1 
ATOM   1476  N N   . ILE A 1 202 ? 9.975   -23.804 76.095  1.00 35.84  ? 221 ILE A N   1 
ATOM   1477  C CA  . ILE A 1 202 ? 8.545   -23.557 76.193  1.00 33.95  ? 221 ILE A CA  1 
ATOM   1478  C C   . ILE A 1 202 ? 7.777   -24.422 75.221  1.00 35.31  ? 221 ILE A C   1 
ATOM   1479  O O   . ILE A 1 202 ? 6.574   -24.624 75.420  1.00 33.66  ? 221 ILE A O   1 
ATOM   1480  C CB  . ILE A 1 202 ? 8.189   -22.060 75.970  1.00 32.36  ? 221 ILE A CB  1 
ATOM   1481  C CG1 . ILE A 1 202 ? 8.349   -21.600 74.517  1.00 33.79  ? 221 ILE A CG1 1 
ATOM   1482  C CG2 . ILE A 1 202 ? 9.013   -21.205 76.893  1.00 31.74  ? 221 ILE A CG2 1 
ATOM   1483  C CD1 . ILE A 1 202 ? 7.853   -20.151 74.286  1.00 30.71  ? 221 ILE A CD1 1 
ATOM   1484  N N   . GLY A 1 203 ? 8.413   -24.910 74.170  1.00 35.99  ? 222 GLY A N   1 
ATOM   1485  C CA  . GLY A 1 203 ? 7.763   -25.785 73.218  1.00 36.73  ? 222 GLY A CA  1 
ATOM   1486  C C   . GLY A 1 203 ? 7.247   -25.029 72.009  1.00 36.11  ? 222 GLY A C   1 
ATOM   1487  O O   . GLY A 1 203 ? 7.267   -23.802 71.944  1.00 35.26  ? 222 GLY A O   1 
ATOM   1488  N N   . ASP A 1 204 ? 6.734   -25.799 71.054  1.00 36.84  ? 223 ASP A N   1 
ATOM   1489  C CA  . ASP A 1 204 ? 6.385   -25.311 69.727  1.00 36.16  ? 223 ASP A CA  1 
ATOM   1490  C C   . ASP A 1 204 ? 5.030   -24.647 69.693  1.00 35.79  ? 223 ASP A C   1 
ATOM   1491  O O   . ASP A 1 204 ? 4.778   -23.832 68.793  1.00 35.59  ? 223 ASP A O   1 
ATOM   1492  C CB  . ASP A 1 204 ? 6.434   -26.483 68.752  1.00 37.50  ? 223 ASP A CB  1 
ATOM   1493  C CG  . ASP A 1 204 ? 7.789   -27.125 68.761  1.00 38.54  ? 223 ASP A CG  1 
ATOM   1494  O OD1 . ASP A 1 204 ? 8.775   -26.367 68.743  1.00 37.82  ? 223 ASP A OD1 1 
ATOM   1495  O OD2 . ASP A 1 204 ? 7.898   -28.353 68.889  1.00 41.10  ? 223 ASP A OD2 1 
ATOM   1496  N N   . ASP A 1 205 ? 4.179   -24.953 70.660  1.00 36.87  ? 224 ASP A N   1 
ATOM   1497  C CA  . ASP A 1 205 ? 2.816   -24.445 70.717  1.00 36.54  ? 224 ASP A CA  1 
ATOM   1498  C C   . ASP A 1 205 ? 2.684   -23.130 71.488  1.00 35.31  ? 224 ASP A C   1 
ATOM   1499  O O   . ASP A 1 205 ? 1.566   -22.734 71.819  1.00 35.23  ? 224 ASP A O   1 
ATOM   1500  C CB  . ASP A 1 205 ? 1.913   -25.496 71.365  1.00 38.29  ? 224 ASP A CB  1 
ATOM   1501  C CG  . ASP A 1 205 ? 2.422   -25.949 72.765  1.00 39.76  ? 224 ASP A CG  1 
ATOM   1502  O OD1 . ASP A 1 205 ? 3.539   -25.541 73.146  1.00 39.39  ? 224 ASP A OD1 1 
ATOM   1503  O OD2 . ASP A 1 205 ? 1.719   -26.749 73.465  1.00 41.95  ? 224 ASP A OD2 1 
ATOM   1504  N N   . LYS A 1 206 ? 3.798   -22.476 71.800  1.00 34.06  ? 225 LYS A N   1 
ATOM   1505  C CA  . LYS A 1 206 ? 3.822   -21.259 72.591  1.00 33.18  ? 225 LYS A CA  1 
ATOM   1506  C C   . LYS A 1 206 ? 4.402   -20.134 71.744  1.00 31.93  ? 225 LYS A C   1 
ATOM   1507  O O   . LYS A 1 206 ? 5.263   -20.358 70.887  1.00 32.30  ? 225 LYS A O   1 
ATOM   1508  C CB  . LYS A 1 206 ? 4.656   -21.444 73.849  1.00 33.92  ? 225 LYS A CB  1 
ATOM   1509  C CG  . LYS A 1 206 ? 4.195   -22.552 74.754  1.00 34.78  ? 225 LYS A CG  1 
ATOM   1510  C CD  . LYS A 1 206 ? 2.865   -22.207 75.398  1.00 34.67  ? 225 LYS A CD  1 
ATOM   1511  C CE  . LYS A 1 206 ? 2.560   -23.257 76.432  1.00 35.63  ? 225 LYS A CE  1 
ATOM   1512  N NZ  . LYS A 1 206 ? 1.449   -22.859 77.270  1.00 35.52  ? 225 LYS A NZ  1 
ATOM   1513  N N   . LEU A 1 207 ? 3.948   -18.919 71.995  1.00 33.71  ? 226 LEU A N   1 
ATOM   1514  C CA  . LEU A 1 207 ? 4.360   -17.767 71.183  1.00 32.03  ? 226 LEU A CA  1 
ATOM   1515  C C   . LEU A 1 207 ? 5.652   -17.143 71.689  1.00 31.79  ? 226 LEU A C   1 
ATOM   1516  O O   . LEU A 1 207 ? 5.855   -17.010 72.897  1.00 32.36  ? 226 LEU A O   1 
ATOM   1517  C CB  . LEU A 1 207 ? 3.251   -16.720 71.170  1.00 30.75  ? 226 LEU A CB  1 
ATOM   1518  C CG  . LEU A 1 207 ? 2.042   -17.179 70.351  1.00 30.83  ? 226 LEU A CG  1 
ATOM   1519  C CD1 . LEU A 1 207 ? 0.770   -16.465 70.743  1.00 30.26  ? 226 LEU A CD1 1 
ATOM   1520  C CD2 . LEU A 1 207 ? 2.394   -16.996 68.867  1.00 30.45  ? 226 LEU A CD2 1 
ATOM   1521  N N   . ILE A 1 208 ? 6.555   -16.818 70.770  1.00 31.61  ? 227 ILE A N   1 
ATOM   1522  C CA  . ILE A 1 208 ? 7.736   -16.036 71.118  1.00 31.17  ? 227 ILE A CA  1 
ATOM   1523  C C   . ILE A 1 208 ? 7.605   -14.693 70.411  1.00 29.80  ? 227 ILE A C   1 
ATOM   1524  O O   . ILE A 1 208 ? 7.746   -14.613 69.183  1.00 29.57  ? 227 ILE A O   1 
ATOM   1525  C CB  . ILE A 1 208 ? 9.044   -16.731 70.741  1.00 32.05  ? 227 ILE A CB  1 
ATOM   1526  C CG1 . ILE A 1 208 ? 9.259   -17.984 71.606  1.00 33.30  ? 227 ILE A CG1 1 
ATOM   1527  C CG2 . ILE A 1 208 ? 10.199  -15.792 70.954  1.00 31.89  ? 227 ILE A CG2 1 
ATOM   1528  C CD1 . ILE A 1 208 ? 10.516  -18.693 71.299  1.00 33.91  ? 227 ILE A CD1 1 
ATOM   1529  N N   . VAL A 1 209 ? 7.299   -13.647 71.179  1.00 30.83  ? 228 VAL A N   1 
ATOM   1530  C CA  . VAL A 1 209 ? 7.195   -12.274 70.678  1.00 29.64  ? 228 VAL A CA  1 
ATOM   1531  C C   . VAL A 1 209 ? 8.471   -11.542 71.044  1.00 29.92  ? 228 VAL A C   1 
ATOM   1532  O O   . VAL A 1 209 ? 8.964   -11.659 72.168  1.00 30.76  ? 228 VAL A O   1 
ATOM   1533  C CB  . VAL A 1 209 ? 5.983   -11.524 71.269  1.00 28.86  ? 228 VAL A CB  1 
ATOM   1534  C CG1 . VAL A 1 209 ? 5.789   -10.207 70.566  1.00 27.57  ? 228 VAL A CG1 1 
ATOM   1535  C CG2 . VAL A 1 209 ? 4.713   -12.337 71.171  1.00 29.08  ? 228 VAL A CG2 1 
ATOM   1536  N N   . TYR A 1 210 ? 8.992   -10.748 70.137  1.00 30.33  ? 229 TYR A N   1 
ATOM   1537  C CA  . TYR A 1 210 ? 10.166  -9.991  70.504  1.00 30.73  ? 229 TYR A CA  1 
ATOM   1538  C C   . TYR A 1 210 ? 10.084  -8.571  69.969  1.00 30.16  ? 229 TYR A C   1 
ATOM   1539  O O   . TYR A 1 210 ? 9.226   -8.221  69.148  1.00 29.62  ? 229 TYR A O   1 
ATOM   1540  C CB  . TYR A 1 210 ? 11.441  -10.714 70.061  1.00 31.75  ? 229 TYR A CB  1 
ATOM   1541  C CG  . TYR A 1 210 ? 11.843  -10.488 68.650  1.00 31.60  ? 229 TYR A CG  1 
ATOM   1542  C CD1 . TYR A 1 210 ? 11.370  -11.319 67.637  1.00 31.80  ? 229 TYR A CD1 1 
ATOM   1543  C CD2 . TYR A 1 210 ? 12.721  -9.487  68.319  1.00 31.98  ? 229 TYR A CD2 1 
ATOM   1544  C CE1 . TYR A 1 210 ? 11.744  -11.139 66.335  1.00 32.22  ? 229 TYR A CE1 1 
ATOM   1545  C CE2 . TYR A 1 210 ? 13.102  -9.286  67.016  1.00 32.42  ? 229 TYR A CE2 1 
ATOM   1546  C CZ  . TYR A 1 210 ? 12.602  -10.119 66.023  1.00 32.54  ? 229 TYR A CZ  1 
ATOM   1547  O OH  . TYR A 1 210 ? 12.980  -9.960  64.704  1.00 33.42  ? 229 TYR A OH  1 
ATOM   1548  N N   . ASN A 1 211 ? 10.996  -7.757  70.511  1.00 30.91  ? 230 ASN A N   1 
ATOM   1549  C CA  . ASN A 1 211 ? 11.151  -6.326  70.264  1.00 31.08  ? 230 ASN A CA  1 
ATOM   1550  C C   . ASN A 1 211 ? 12.572  -6.167  69.740  1.00 32.08  ? 230 ASN A C   1 
ATOM   1551  O O   . ASN A 1 211 ? 13.513  -6.187  70.518  1.00 32.92  ? 230 ASN A O   1 
ATOM   1552  C CB  . ASN A 1 211 ? 10.924  -5.554  71.553  1.00 31.49  ? 230 ASN A CB  1 
ATOM   1553  C CG  . ASN A 1 211 ? 10.770  -4.085  71.309  1.00 31.94  ? 230 ASN A CG  1 
ATOM   1554  O OD1 . ASN A 1 211 ? 10.690  -3.681  70.158  1.00 32.27  ? 230 ASN A OD1 1 
ATOM   1555  N ND2 . ASN A 1 211 ? 10.704  -3.265  72.394  1.00 32.46  ? 230 ASN A ND2 1 
ATOM   1556  N N   . GLY A 1 212 ? 12.765  -6.027  68.438  1.00 30.75  ? 231 GLY A N   1 
ATOM   1557  C CA  . GLY A 1 212 ? 11.718  -5.880  67.451  1.00 29.78  ? 231 GLY A CA  1 
ATOM   1558  C C   . GLY A 1 212 ? 12.237  -5.329  66.151  1.00 30.19  ? 231 GLY A C   1 
ATOM   1559  O O   . GLY A 1 212 ? 13.452  -5.282  65.888  1.00 31.64  ? 231 GLY A O   1 
ATOM   1560  N N   . ILE A 1 213 ? 11.304  -4.916  65.346  1.00 32.12  ? 232 ILE A N   1 
ATOM   1561  C CA  . ILE A 1 213 ? 11.616  -4.190  64.126  1.00 32.30  ? 232 ILE A CA  1 
ATOM   1562  C C   . ILE A 1 213 ? 11.873  -2.743  64.482  1.00 32.99  ? 232 ILE A C   1 
ATOM   1563  O O   . ILE A 1 213 ? 11.156  -2.154  65.291  1.00 32.73  ? 232 ILE A O   1 
ATOM   1564  C CB  . ILE A 1 213 ? 10.469  -4.320  63.108  1.00 31.27  ? 232 ILE A CB  1 
ATOM   1565  C CG1 . ILE A 1 213 ? 10.299  -5.802  62.725  1.00 31.35  ? 232 ILE A CG1 1 
ATOM   1566  C CG2 . ILE A 1 213 ? 10.703  -3.405  61.885  1.00 31.85  ? 232 ILE A CG2 1 
ATOM   1567  C CD1 . ILE A 1 213 ? 8.892   -6.104  62.223  1.00 30.36  ? 232 ILE A CD1 1 
ATOM   1568  N N   . ARG A 1 214 ? 12.905  -2.167  63.881  1.00 31.39  ? 233 ARG A N   1 
ATOM   1569  C CA  . ARG A 1 214 ? 13.353  -0.844  64.299  1.00 32.66  ? 233 ARG A CA  1 
ATOM   1570  C C   . ARG A 1 214 ? 14.079  -0.203  63.138  1.00 33.34  ? 233 ARG A C   1 
ATOM   1571  O O   . ARG A 1 214 ? 15.024  -0.782  62.599  1.00 33.99  ? 233 ARG A O   1 
ATOM   1572  C CB  . ARG A 1 214 ? 14.238  -0.952  65.527  1.00 33.97  ? 233 ARG A CB  1 
ATOM   1573  C CG  . ARG A 1 214 ? 14.802  0.351   66.024  1.00 35.93  ? 233 ARG A CG  1 
ATOM   1574  C CD  . ARG A 1 214 ? 13.747  1.260   66.566  1.00 35.95  ? 233 ARG A CD  1 
ATOM   1575  N NE  . ARG A 1 214 ? 12.872  0.631   67.538  1.00 34.92  ? 233 ARG A NE  1 
ATOM   1576  C CZ  . ARG A 1 214 ? 13.226  0.335   68.772  1.00 35.54  ? 233 ARG A CZ  1 
ATOM   1577  N NH1 . ARG A 1 214 ? 14.464  0.489   69.176  1.00 36.69  ? 233 ARG A NH1 1 
ATOM   1578  N NH2 . ARG A 1 214 ? 12.303  -0.101  69.622  1.00 34.93  ? 233 ARG A NH2 1 
ATOM   1579  N N   . SER A 1 215 ? 13.638  0.981   62.742  1.00 36.15  ? 234 SER A N   1 
ATOM   1580  C CA  . SER A 1 215 ? 14.219  1.669   61.596  1.00 36.89  ? 234 SER A CA  1 
ATOM   1581  C C   . SER A 1 215 ? 14.598  3.080   62.019  1.00 38.46  ? 234 SER A C   1 
ATOM   1582  O O   . SER A 1 215 ? 13.751  3.854   62.485  1.00 38.53  ? 234 SER A O   1 
ATOM   1583  C CB  . SER A 1 215 ? 13.246  1.704   60.411  1.00 36.16  ? 234 SER A CB  1 
ATOM   1584  O OG  . SER A 1 215 ? 12.895  0.391   60.014  1.00 35.46  ? 234 SER A OG  1 
ATOM   1585  N N   . THR A 1 216 ? 15.872  3.402   61.868  1.00 38.45  ? 235 THR A N   1 
ATOM   1586  C CA  . THR A 1 216 ? 16.409  4.688   62.263  1.00 40.41  ? 235 THR A CA  1 
ATOM   1587  C C   . THR A 1 216 ? 17.489  5.035   61.246  1.00 41.80  ? 235 THR A C   1 
ATOM   1588  O O   . THR A 1 216 ? 17.991  4.152   60.553  1.00 41.95  ? 235 THR A O   1 
ATOM   1589  C CB  . THR A 1 216 ? 17.004  4.672   63.668  1.00 41.35  ? 235 THR A CB  1 
ATOM   1590  O OG1 . THR A 1 216 ? 18.259  4.000   63.638  1.00 42.20  ? 235 THR A OG1 1 
ATOM   1591  C CG2 . THR A 1 216 ? 16.078  3.995   64.649  1.00 40.51  ? 235 THR A CG2 1 
ATOM   1592  N N   . PRO A 1 217 ? 17.843  6.313   61.141  1.00 42.09  ? 236 PRO A N   1 
ATOM   1593  C CA  . PRO A 1 217 ? 18.827  6.692   60.110  1.00 43.74  ? 236 PRO A CA  1 
ATOM   1594  C C   . PRO A 1 217 ? 20.173  6.009   60.243  1.00 45.35  ? 236 PRO A C   1 
ATOM   1595  O O   . PRO A 1 217 ? 20.842  5.828   59.222  1.00 46.42  ? 236 PRO A O   1 
ATOM   1596  C CB  . PRO A 1 217 ? 18.935  8.211   60.289  1.00 44.81  ? 236 PRO A CB  1 
ATOM   1597  C CG  . PRO A 1 217 ? 17.543  8.594   60.837  1.00 44.30  ? 236 PRO A CG  1 
ATOM   1598  C CD  . PRO A 1 217 ? 17.154  7.475   61.740  1.00 42.90  ? 236 PRO A CD  1 
ATOM   1599  N N   . ASP A 1 218 ? 20.605  5.624   61.449  1.00 47.68  ? 237 ASP A N   1 
ATOM   1600  C CA  . ASP A 1 218 ? 21.921  5.013   61.616  1.00 49.39  ? 237 ASP A CA  1 
ATOM   1601  C C   . ASP A 1 218 ? 21.900  3.508   61.885  1.00 48.70  ? 237 ASP A C   1 
ATOM   1602  O O   . ASP A 1 218 ? 22.909  2.843   61.625  1.00 49.99  ? 237 ASP A O   1 
ATOM   1603  C CB  . ASP A 1 218 ? 22.681  5.700   62.759  1.00 51.22  ? 237 ASP A CB  1 
ATOM   1604  C CG  . ASP A 1 218 ? 23.195  7.074   62.378  1.00 53.34  ? 237 ASP A CG  1 
ATOM   1605  O OD1 . ASP A 1 218 ? 23.508  7.275   61.163  1.00 53.49  ? 237 ASP A OD1 1 
ATOM   1606  O OD2 . ASP A 1 218 ? 23.299  7.955   63.265  1.00 55.10  ? 237 ASP A OD2 1 
ATOM   1607  N N   . TRP A 1 219 ? 20.787  2.953   62.363  1.00 42.88  ? 238 TRP A N   1 
ATOM   1608  C CA  . TRP A 1 219 ? 20.729  1.540   62.707  1.00 41.66  ? 238 TRP A CA  1 
ATOM   1609  C C   . TRP A 1 219 ? 19.297  1.055   62.560  1.00 39.76  ? 238 TRP A C   1 
ATOM   1610  O O   . TRP A 1 219 ? 18.376  1.655   63.131  1.00 39.56  ? 238 TRP A O   1 
ATOM   1611  C CB  . TRP A 1 219 ? 21.208  1.294   64.145  1.00 42.32  ? 238 TRP A CB  1 
ATOM   1612  C CG  . TRP A 1 219 ? 21.329  -0.155  64.528  1.00 42.08  ? 238 TRP A CG  1 
ATOM   1613  C CD1 . TRP A 1 219 ? 22.461  -0.942  64.452  1.00 43.13  ? 238 TRP A CD1 1 
ATOM   1614  C CD2 . TRP A 1 219 ? 20.287  -1.006  65.040  1.00 40.75  ? 238 TRP A CD2 1 
ATOM   1615  N NE1 . TRP A 1 219 ? 22.179  -2.221  64.893  1.00 42.60  ? 238 TRP A NE1 1 
ATOM   1616  C CE2 . TRP A 1 219 ? 20.853  -2.286  65.249  1.00 40.96  ? 238 TRP A CE2 1 
ATOM   1617  C CE3 . TRP A 1 219 ? 18.942  -0.810  65.339  1.00 39.39  ? 238 TRP A CE3 1 
ATOM   1618  C CZ2 . TRP A 1 219 ? 20.121  -3.340  65.748  1.00 39.73  ? 238 TRP A CZ2 1 
ATOM   1619  C CZ3 . TRP A 1 219 ? 18.227  -1.856  65.856  1.00 38.37  ? 238 TRP A CZ3 1 
ATOM   1620  C CH2 . TRP A 1 219 ? 18.812  -3.107  66.052  1.00 38.54  ? 238 TRP A CH2 1 
ATOM   1621  N N   . SER A 1 220 ? 19.114  -0.045  61.827  1.00 39.87  ? 239 SER A N   1 
ATOM   1622  C CA  . SER A 1 220 ? 17.779  -0.600  61.623  1.00 38.11  ? 239 SER A CA  1 
ATOM   1623  C C   . SER A 1 220 ? 17.829  -2.107  61.748  1.00 36.61  ? 239 SER A C   1 
ATOM   1624  O O   . SER A 1 220 ? 18.864  -2.732  61.557  1.00 37.98  ? 239 SER A O   1 
ATOM   1625  C CB  . SER A 1 220 ? 17.188  -0.231  60.252  1.00 38.31  ? 239 SER A CB  1 
ATOM   1626  O OG  . SER A 1 220 ? 17.072  1.172   60.106  1.00 39.36  ? 239 SER A OG  1 
ATOM   1627  N N   . ALA A 1 221 ? 16.675  -2.686  62.028  1.00 35.86  ? 240 ALA A N   1 
ATOM   1628  C CA  . ALA A 1 221 ? 16.550  -4.123  62.130  1.00 34.81  ? 240 ALA A CA  1 
ATOM   1629  C C   . ALA A 1 221 ? 15.207  -4.553  61.588  1.00 33.14  ? 240 ALA A C   1 
ATOM   1630  O O   . ALA A 1 221 ? 14.170  -4.007  61.959  1.00 32.32  ? 240 ALA A O   1 
ATOM   1631  C CB  . ALA A 1 221 ? 16.694  -4.583  63.589  1.00 35.45  ? 240 ALA A CB  1 
ATOM   1632  N N   . GLY A 1 222 ? 15.219  -5.583  60.754  1.00 35.93  ? 241 GLY A N   1 
ATOM   1633  C CA  . GLY A 1 222 ? 14.011  -6.255  60.350  1.00 34.78  ? 241 GLY A CA  1 
ATOM   1634  C C   . GLY A 1 222 ? 13.762  -7.494  61.187  1.00 34.43  ? 241 GLY A C   1 
ATOM   1635  O O   . GLY A 1 222 ? 14.447  -7.745  62.181  1.00 35.34  ? 241 GLY A O   1 
ATOM   1636  N N   . PHE A 1 223 ? 12.754  -8.270  60.766  1.00 32.80  ? 242 PHE A N   1 
ATOM   1637  C CA  . PHE A 1 223 ? 12.452  -9.544  61.421  1.00 32.69  ? 242 PHE A CA  1 
ATOM   1638  C C   . PHE A 1 223 ? 13.647  -10.482 61.286  1.00 33.99  ? 242 PHE A C   1 
ATOM   1639  O O   . PHE A 1 223 ? 14.154  -10.669 60.180  1.00 34.81  ? 242 PHE A O   1 
ATOM   1640  C CB  . PHE A 1 223 ? 11.196  -10.142 60.777  1.00 31.77  ? 242 PHE A CB  1 
ATOM   1641  C CG  . PHE A 1 223 ? 10.311  -10.922 61.729  1.00 31.30  ? 242 PHE A CG  1 
ATOM   1642  C CD1 . PHE A 1 223 ? 10.739  -12.133 62.249  1.00 32.32  ? 242 PHE A CD1 1 
ATOM   1643  C CD2 . PHE A 1 223 ? 9.048   -10.453 62.075  1.00 30.13  ? 242 PHE A CD2 1 
ATOM   1644  C CE1 . PHE A 1 223 ? 9.948   -12.837 63.107  1.00 32.63  ? 242 PHE A CE1 1 
ATOM   1645  C CE2 . PHE A 1 223 ? 8.250   -11.151 62.939  1.00 30.47  ? 242 PHE A CE2 1 
ATOM   1646  C CZ  . PHE A 1 223 ? 8.699   -12.339 63.463  1.00 31.54  ? 242 PHE A CZ  1 
ATOM   1647  N N   . ASP A 1 224 ? 14.127  -11.017 62.425  1.00 33.98  ? 243 ASP A N   1 
ATOM   1648  C CA  . ASP A 1 224 ? 15.271  -11.932 62.481  1.00 35.54  ? 243 ASP A CA  1 
ATOM   1649  C C   . ASP A 1 224 ? 14.944  -13.154 63.343  1.00 35.19  ? 243 ASP A C   1 
ATOM   1650  O O   . ASP A 1 224 ? 13.884  -13.274 63.955  1.00 34.76  ? 243 ASP A O   1 
ATOM   1651  C CB  . ASP A 1 224 ? 16.539  -11.260 63.037  1.00 37.62  ? 243 ASP A CB  1 
ATOM   1652  N N   . PHE A 1 225 ? 15.869  -14.100 63.352  1.00 39.00  ? 244 PHE A N   1 
ATOM   1653  C CA  . PHE A 1 225 ? 15.746  -15.268 64.222  1.00 39.43  ? 244 PHE A CA  1 
ATOM   1654  C C   . PHE A 1 225 ? 14.510  -16.106 63.903  1.00 39.10  ? 244 PHE A C   1 
ATOM   1655  O O   . PHE A 1 225 ? 14.031  -16.877 64.778  1.00 39.23  ? 244 PHE A O   1 
ATOM   1656  C CB  . PHE A 1 225 ? 15.691  -14.821 65.696  1.00 39.44  ? 244 PHE A CB  1 
ATOM   1657  C CG  . PHE A 1 225 ? 16.722  -13.756 66.068  1.00 40.01  ? 244 PHE A CG  1 
ATOM   1658  C CD1 . PHE A 1 225 ? 18.045  -14.130 66.329  1.00 41.42  ? 244 PHE A CD1 1 
ATOM   1659  C CD2 . PHE A 1 225 ? 16.381  -12.427 66.163  1.00 39.68  ? 244 PHE A CD2 1 
ATOM   1660  C CE1 . PHE A 1 225 ? 18.998  -13.187 66.689  1.00 42.03  ? 244 PHE A CE1 1 
ATOM   1661  C CE2 . PHE A 1 225 ? 17.343  -11.488 66.514  1.00 40.32  ? 244 PHE A CE2 1 
ATOM   1662  C CZ  . PHE A 1 225 ? 18.647  -11.864 66.771  1.00 41.50  ? 244 PHE A CZ  1 
ATOM   1663  N N   . ALA A 1 226 ? 14.000  -15.954 62.668  1.00 38.71  ? 245 ALA A N   1 
ATOM   1664  C CA  . ALA A 1 226 ? 12.665  -16.425 62.347  1.00 38.45  ? 245 ALA A CA  1 
ATOM   1665  C C   . ALA A 1 226 ? 12.520  -17.914 62.483  1.00 39.37  ? 245 ALA A C   1 
ATOM   1666  O O   . ALA A 1 226 ? 11.388  -18.391 62.627  1.00 39.26  ? 245 ALA A O   1 
ATOM   1667  C CB  . ALA A 1 226 ? 12.265  -16.044 60.917  1.00 38.43  ? 245 ALA A CB  1 
ATOM   1668  N N   . GLU A 1 227 ? 13.619  -18.673 62.437  1.00 38.74  ? 246 GLU A N   1 
ATOM   1669  C CA  . GLU A 1 227 ? 13.459  -20.108 62.666  1.00 39.83  ? 246 GLU A CA  1 
ATOM   1670  C C   . GLU A 1 227 ? 12.775  -20.357 64.000  1.00 39.67  ? 246 GLU A C   1 
ATOM   1671  O O   . GLU A 1 227 ? 12.222  -21.444 64.202  1.00 40.68  ? 246 GLU A O   1 
ATOM   1672  C CB  . GLU A 1 227 ? 14.786  -20.865 62.646  1.00 41.09  ? 246 GLU A CB  1 
ATOM   1673  N N   . TYR A 1 228 ? 12.829  -19.383 64.923  1.00 36.32  ? 247 TYR A N   1 
ATOM   1674  C CA  . TYR A 1 228 ? 12.335  -19.574 66.275  1.00 36.42  ? 247 TYR A CA  1 
ATOM   1675  C C   . TYR A 1 228 ? 11.315  -18.552 66.724  1.00 35.14  ? 247 TYR A C   1 
ATOM   1676  O O   . TYR A 1 228 ? 10.480  -18.883 67.574  1.00 36.11  ? 247 TYR A O   1 
ATOM   1677  C CB  . TYR A 1 228 ? 13.505  -19.572 67.262  1.00 36.71  ? 247 TYR A CB  1 
ATOM   1678  C CG  . TYR A 1 228 ? 14.538  -20.553 66.885  1.00 37.62  ? 247 TYR A CG  1 
ATOM   1679  C CD1 . TYR A 1 228 ? 14.290  -21.902 66.970  1.00 38.24  ? 247 TYR A CD1 1 
ATOM   1680  C CD2 . TYR A 1 228 ? 15.745  -20.148 66.385  1.00 38.24  ? 247 TYR A CD2 1 
ATOM   1681  C CE1 . TYR A 1 228 ? 15.258  -22.824 66.601  1.00 39.35  ? 247 TYR A CE1 1 
ATOM   1682  C CE2 . TYR A 1 228 ? 16.705  -21.052 66.006  1.00 39.53  ? 247 TYR A CE2 1 
ATOM   1683  C CZ  . TYR A 1 228 ? 16.476  -22.383 66.116  1.00 39.87  ? 247 TYR A CZ  1 
ATOM   1684  O OH  . TYR A 1 228 ? 17.487  -23.259 65.736  1.00 41.71  ? 247 TYR A OH  1 
ATOM   1685  N N   . THR A 1 229 ? 11.345  -17.335 66.197  1.00 36.05  ? 248 THR A N   1 
ATOM   1686  C CA  . THR A 1 229 ? 10.430  -16.323 66.676  1.00 35.11  ? 248 THR A CA  1 
ATOM   1687  C C   . THR A 1 229 ? 9.152   -16.320 65.849  1.00 34.29  ? 248 THR A C   1 
ATOM   1688  O O   . THR A 1 229 ? 9.152   -16.660 64.661  1.00 34.80  ? 248 THR A O   1 
ATOM   1689  C CB  . THR A 1 229 ? 11.096  -14.959 66.636  1.00 34.91  ? 248 THR A CB  1 
ATOM   1690  O OG1 . THR A 1 229 ? 11.550  -14.654 65.310  1.00 35.12  ? 248 THR A OG1 1 
ATOM   1691  C CG2 . THR A 1 229 ? 12.301  -14.949 67.557  1.00 35.56  ? 248 THR A CG2 1 
ATOM   1692  N N   . ASP A 1 230 ? 8.051   -15.948 66.504  1.00 32.22  ? 249 ASP A N   1 
ATOM   1693  C CA  . ASP A 1 230 ? 6.730   -15.898 65.908  1.00 31.53  ? 249 ASP A CA  1 
ATOM   1694  C C   . ASP A 1 230 ? 6.292   -14.496 65.555  1.00 30.40  ? 249 ASP A C   1 
ATOM   1695  O O   . ASP A 1 230 ? 5.577   -14.316 64.568  1.00 29.54  ? 249 ASP A O   1 
ATOM   1696  C CB  . ASP A 1 230 ? 5.681   -16.475 66.867  1.00 32.25  ? 249 ASP A CB  1 
ATOM   1697  C CG  . ASP A 1 230 ? 5.890   -17.945 67.135  1.00 33.97  ? 249 ASP A CG  1 
ATOM   1698  O OD1 . ASP A 1 230 ? 5.850   -18.696 66.146  1.00 34.70  ? 249 ASP A OD1 1 
ATOM   1699  O OD2 . ASP A 1 230 ? 6.100   -18.339 68.316  1.00 34.83  ? 249 ASP A OD2 1 
ATOM   1700  N N   . ALA A 1 231 ? 6.659   -13.514 66.391  1.00 30.39  ? 250 ALA A N   1 
ATOM   1701  C CA  . ALA A 1 231 ? 6.092   -12.171 66.365  1.00 29.07  ? 250 ALA A CA  1 
ATOM   1702  C C   . ALA A 1 231 ? 7.179   -11.165 66.672  1.00 28.94  ? 250 ALA A C   1 
ATOM   1703  O O   . ALA A 1 231 ? 8.040   -11.409 67.517  1.00 29.97  ? 250 ALA A O   1 
ATOM   1704  C CB  . ALA A 1 231 ? 4.944   -11.995 67.374  1.00 28.98  ? 250 ALA A CB  1 
ATOM   1705  N N   . ALA A 1 232 ? 7.134   -10.053 65.966  1.00 29.11  ? 251 ALA A N   1 
ATOM   1706  C CA  . ALA A 1 232 ? 8.010   -8.924  66.212  1.00 29.32  ? 251 ALA A CA  1 
ATOM   1707  C C   . ALA A 1 232 ? 7.162   -7.667  66.340  1.00 28.45  ? 251 ALA A C   1 
ATOM   1708  O O   . ALA A 1 232 ? 6.135   -7.508  65.649  1.00 27.67  ? 251 ALA A O   1 
ATOM   1709  C CB  . ALA A 1 232 ? 9.036   -8.749  65.103  1.00 29.99  ? 251 ALA A CB  1 
ATOM   1710  N N   . MET A 1 233 ? 7.565   -6.808  67.267  1.00 31.88  ? 252 MET A N   1 
ATOM   1711  C CA  . MET A 1 233 ? 6.885   -5.548  67.515  1.00 31.02  ? 252 MET A CA  1 
ATOM   1712  C C   . MET A 1 233 ? 7.642   -4.433  66.808  1.00 31.66  ? 252 MET A C   1 
ATOM   1713  O O   . MET A 1 233 ? 8.872   -4.456  66.732  1.00 33.10  ? 252 MET A O   1 
ATOM   1714  C CB  . MET A 1 233 ? 6.774   -5.263  69.012  1.00 31.64  ? 252 MET A CB  1 
ATOM   1715  C CG  . MET A 1 233 ? 6.182   -3.862  69.334  1.00 31.65  ? 252 MET A CG  1 
ATOM   1716  S SD  . MET A 1 233 ? 6.541   -3.386  71.079  1.00 31.96  ? 252 MET A SD  1 
ATOM   1717  C CE  . MET A 1 233 ? 4.900   -3.639  71.793  1.00 31.55  ? 252 MET A CE  1 
ATOM   1718  N N   . ILE A 1 234 ? 6.886   -3.506  66.228  1.00 30.10  ? 253 ILE A N   1 
ATOM   1719  C CA  . ILE A 1 234 ? 7.424   -2.234  65.704  1.00 30.62  ? 253 ILE A CA  1 
ATOM   1720  C C   . ILE A 1 234 ? 7.094   -1.186  66.759  1.00 30.63  ? 253 ILE A C   1 
ATOM   1721  O O   . ILE A 1 234 ? 6.008   -0.619  66.790  1.00 29.96  ? 253 ILE A O   1 
ATOM   1722  C CB  . ILE A 1 234 ? 6.845   -1.856  64.341  1.00 30.21  ? 253 ILE A CB  1 
ATOM   1723  C CG1 . ILE A 1 234 ? 6.973   -3.023  63.353  1.00 30.29  ? 253 ILE A CG1 1 
ATOM   1724  C CG2 . ILE A 1 234 ? 7.545   -0.587  63.839  1.00 31.82  ? 253 ILE A CG2 1 
ATOM   1725  C CD1 . ILE A 1 234 ? 6.208   -2.838  62.006  1.00 29.80  ? 253 ILE A CD1 1 
ATOM   1726  N N   . GLU A 1 235 ? 8.030   -0.971  67.653  1.00 32.00  ? 254 GLU A N   1 
ATOM   1727  C CA  . GLU A 1 235 ? 7.708   -0.280  68.884  1.00 31.77  ? 254 GLU A CA  1 
ATOM   1728  C C   . GLU A 1 235 ? 7.637   1.215   68.661  1.00 32.30  ? 254 GLU A C   1 
ATOM   1729  O O   . GLU A 1 235 ? 6.785   1.885   69.262  1.00 31.73  ? 254 GLU A O   1 
ATOM   1730  C CB  . GLU A 1 235 ? 8.744   -0.610  69.976  1.00 33.18  ? 254 GLU A CB  1 
ATOM   1731  C CG  . GLU A 1 235 ? 8.258   -0.226  71.357  1.00 33.00  ? 254 GLU A CG  1 
ATOM   1732  C CD  . GLU A 1 235 ? 9.348   0.051   72.400  1.00 34.50  ? 254 GLU A CD  1 
ATOM   1733  O OE1 . GLU A 1 235 ? 10.521  -0.395  72.248  1.00 33.95  ? 254 GLU A OE1 1 
ATOM   1734  O OE2 . GLU A 1 235 ? 8.991   0.728   73.410  1.00 36.20  ? 254 GLU A OE2 1 
ATOM   1735  N N   . HIS A 1 236 ? 8.472   1.745   67.780  1.00 30.03  ? 255 HIS A N   1 
ATOM   1736  C CA  . HIS A 1 236 ? 8.654   3.187   67.658  1.00 31.16  ? 255 HIS A CA  1 
ATOM   1737  C C   . HIS A 1 236 ? 8.121   3.762   66.354  1.00 30.89  ? 255 HIS A C   1 
ATOM   1738  O O   . HIS A 1 236 ? 8.730   4.651   65.764  1.00 32.63  ? 255 HIS A O   1 
ATOM   1739  C CB  . HIS A 1 236 ? 10.128  3.560   67.743  1.00 33.84  ? 255 HIS A CB  1 
ATOM   1740  C CG  . HIS A 1 236 ? 10.713  3.389   69.093  1.00 34.78  ? 255 HIS A CG  1 
ATOM   1741  N ND1 . HIS A 1 236 ? 12.035  3.663   69.362  1.00 35.96  ? 255 HIS A ND1 1 
ATOM   1742  C CD2 . HIS A 1 236 ? 10.156  2.985   70.257  1.00 33.30  ? 255 HIS A CD2 1 
ATOM   1743  C CE1 . HIS A 1 236 ? 12.266  3.440   70.641  1.00 35.54  ? 255 HIS A CE1 1 
ATOM   1744  N NE2 . HIS A 1 236 ? 11.143  3.014   71.203  1.00 34.36  ? 255 HIS A NE2 1 
ATOM   1745  N N   . PHE A 1 237 ? 6.989   3.265   65.865  1.00 34.66  ? 256 PHE A N   1 
ATOM   1746  C CA  . PHE A 1 237 ? 6.543   3.729   64.561  1.00 34.18  ? 256 PHE A CA  1 
ATOM   1747  C C   . PHE A 1 237 ? 6.250   5.236   64.564  1.00 34.84  ? 256 PHE A C   1 
ATOM   1748  O O   . PHE A 1 237 ? 5.434   5.725   65.348  1.00 34.13  ? 256 PHE A O   1 
ATOM   1749  C CB  . PHE A 1 237 ? 5.294   3.011   64.085  1.00 32.44  ? 256 PHE A CB  1 
ATOM   1750  C CG  . PHE A 1 237 ? 4.871   3.507   62.754  1.00 32.45  ? 256 PHE A CG  1 
ATOM   1751  C CD1 . PHE A 1 237 ? 5.532   3.079   61.635  1.00 33.29  ? 256 PHE A CD1 1 
ATOM   1752  C CD2 . PHE A 1 237 ? 3.906   4.503   62.636  1.00 32.15  ? 256 PHE A CD2 1 
ATOM   1753  C CE1 . PHE A 1 237 ? 5.190   3.561   60.389  1.00 33.20  ? 256 PHE A CE1 1 
ATOM   1754  C CE2 . PHE A 1 237 ? 3.573   5.010   61.416  1.00 32.53  ? 256 PHE A CE2 1 
ATOM   1755  C CZ  . PHE A 1 237 ? 4.214   4.547   60.271  1.00 32.84  ? 256 PHE A CZ  1 
ATOM   1756  N N   . GLY A 1 238 ? 6.894   5.954   63.640  1.00 34.61  ? 257 GLY A N   1 
ATOM   1757  C CA  . GLY A 1 238 ? 6.655   7.370   63.384  1.00 35.38  ? 257 GLY A CA  1 
ATOM   1758  C C   . GLY A 1 238 ? 7.091   8.335   64.464  1.00 36.99  ? 257 GLY A C   1 
ATOM   1759  O O   . GLY A 1 238 ? 6.642   9.481   64.449  1.00 38.14  ? 257 GLY A O   1 
ATOM   1760  N N   . HIS A 1 239 ? 7.971   7.893   65.374  1.00 35.56  ? 258 HIS A N   1 
ATOM   1761  C CA  . HIS A 1 239 ? 8.366   8.593   66.585  1.00 37.11  ? 258 HIS A CA  1 
ATOM   1762  C C   . HIS A 1 239 ? 9.810   8.256   66.917  1.00 39.01  ? 258 HIS A C   1 
ATOM   1763  O O   . HIS A 1 239 ? 10.451  7.432   66.239  1.00 39.12  ? 258 HIS A O   1 
ATOM   1764  C CB  . HIS A 1 239 ? 7.495   8.199   67.757  1.00 35.28  ? 258 HIS A CB  1 
ATOM   1765  C CG  . HIS A 1 239 ? 6.189   8.886   67.737  1.00 33.88  ? 258 HIS A CG  1 
ATOM   1766  N ND1 . HIS A 1 239 ? 5.909   9.965   68.553  1.00 34.85  ? 258 HIS A ND1 1 
ATOM   1767  C CD2 . HIS A 1 239 ? 5.117   8.733   66.920  1.00 32.64  ? 258 HIS A CD2 1 
ATOM   1768  C CE1 . HIS A 1 239 ? 4.697   10.413  68.272  1.00 33.70  ? 258 HIS A CE1 1 
ATOM   1769  N NE2 . HIS A 1 239 ? 4.196   9.684   67.287  1.00 32.70  ? 258 HIS A NE2 1 
ATOM   1770  N N   . PHE A 1 240 ? 10.304  8.883   68.007  1.00 36.60  ? 259 PHE A N   1 
ATOM   1771  C CA  . PHE A 1 240 ? 11.661  8.703   68.507  1.00 37.16  ? 259 PHE A CA  1 
ATOM   1772  C C   . PHE A 1 240 ? 12.596  8.972   67.334  1.00 38.93  ? 259 PHE A C   1 
ATOM   1773  O O   . PHE A 1 240 ? 12.418  9.994   66.654  1.00 40.39  ? 259 PHE A O   1 
ATOM   1774  C CB  . PHE A 1 240 ? 11.767  7.332   69.133  1.00 36.32  ? 259 PHE A CB  1 
ATOM   1775  C CG  . PHE A 1 240 ? 10.712  7.055   70.151  1.00 34.68  ? 259 PHE A CG  1 
ATOM   1776  C CD1 . PHE A 1 240 ? 10.810  7.583   71.424  1.00 34.58  ? 259 PHE A CD1 1 
ATOM   1777  C CD2 . PHE A 1 240 ? 9.609   6.288   69.836  1.00 33.10  ? 259 PHE A CD2 1 
ATOM   1778  C CE1 . PHE A 1 240 ? 9.829   7.324   72.379  1.00 32.91  ? 259 PHE A CE1 1 
ATOM   1779  C CE2 . PHE A 1 240 ? 8.621   6.062   70.759  1.00 31.46  ? 259 PHE A CE2 1 
ATOM   1780  C CZ  . PHE A 1 240 ? 8.725   6.571   72.026  1.00 31.58  ? 259 PHE A CZ  1 
ATOM   1781  N N   . GLN A 1 241 ? 13.576  8.118   67.067  1.00 35.61  ? 260 GLN A N   1 
ATOM   1782  C CA  . GLN A 1 241 ? 14.458  8.226   65.902  1.00 37.05  ? 260 GLN A CA  1 
ATOM   1783  C C   . GLN A 1 241 ? 13.820  7.644   64.616  1.00 35.82  ? 260 GLN A C   1 
ATOM   1784  O O   . GLN A 1 241 ? 14.542  7.500   63.612  1.00 36.13  ? 260 GLN A O   1 
ATOM   1785  C CB  . GLN A 1 241 ? 15.797  7.538   66.219  1.00 38.59  ? 260 GLN A CB  1 
ATOM   1786  N N   . SER A 1 242 ? 12.509  7.364   64.606  1.00 37.21  ? 261 SER A N   1 
ATOM   1787  C CA  . SER A 1 242 ? 11.897  6.680   63.474  1.00 35.73  ? 261 SER A CA  1 
ATOM   1788  C C   . SER A 1 242 ? 10.790  7.490   62.803  1.00 35.28  ? 261 SER A C   1 
ATOM   1789  O O   . SER A 1 242 ? 10.004  6.942   62.034  1.00 34.20  ? 261 SER A O   1 
ATOM   1790  C CB  . SER A 1 242 ? 11.329  5.317   63.903  1.00 34.32  ? 261 SER A CB  1 
ATOM   1791  O OG  . SER A 1 242 ? 12.289  4.448   64.524  1.00 34.51  ? 261 SER A OG  1 
ATOM   1792  N N   . ALA A 1 243 ? 10.755  8.793   63.013  1.00 36.92  ? 262 ALA A N   1 
ATOM   1793  C CA  . ALA A 1 243 ? 9.658   9.625   62.558  1.00 36.79  ? 262 ALA A CA  1 
ATOM   1794  C C   . ALA A 1 243 ? 9.799   10.089  61.126  1.00 37.30  ? 262 ALA A C   1 
ATOM   1795  O O   . ALA A 1 243 ? 8.848   10.680  60.599  1.00 37.18  ? 262 ALA A O   1 
ATOM   1796  C CB  . ALA A 1 243 ? 9.552   10.867  63.454  1.00 38.35  ? 262 ALA A CB  1 
ATOM   1797  N N   . SER A 1 244 ? 10.959  9.869   60.513  1.00 37.47  ? 263 SER A N   1 
ATOM   1798  C CA  . SER A 1 244 ? 11.197  10.345  59.166  1.00 38.05  ? 263 SER A CA  1 
ATOM   1799  C C   . SER A 1 244 ? 10.379  9.536   58.169  1.00 36.54  ? 263 SER A C   1 
ATOM   1800  O O   . SER A 1 244 ? 9.935   8.439   58.450  1.00 35.29  ? 263 SER A O   1 
ATOM   1801  C CB  . SER A 1 244 ? 12.681  10.283  58.810  1.00 39.37  ? 263 SER A CB  1 
ATOM   1802  O OG  . SER A 1 244 ? 13.077  8.982   58.442  1.00 38.72  ? 263 SER A OG  1 
ATOM   1803  N N   . LYS A 1 245 ? 10.159  10.115  56.992  1.00 38.31  ? 264 LYS A N   1 
ATOM   1804  C CA  . LYS A 1 245 ? 9.392   9.404   55.990  1.00 38.15  ? 264 LYS A CA  1 
ATOM   1805  C C   . LYS A 1 245 ? 10.121  8.127   55.594  1.00 37.26  ? 264 LYS A C   1 
ATOM   1806  O O   . LYS A 1 245 ? 9.491   7.080   55.414  1.00 36.34  ? 264 LYS A O   1 
ATOM   1807  C CB  . LYS A 1 245 ? 9.144   10.298  54.786  1.00 40.09  ? 264 LYS A CB  1 
ATOM   1808  C CG  . LYS A 1 245 ? 10.361  10.672  53.996  1.00 41.33  ? 264 LYS A CG  1 
ATOM   1809  C CD  . LYS A 1 245 ? 9.999   11.794  53.018  1.00 42.99  ? 264 LYS A CD  1 
ATOM   1810  C CE  . LYS A 1 245 ? 11.175  12.244  52.139  1.00 44.49  ? 264 LYS A CE  1 
ATOM   1811  N NZ  . LYS A 1 245 ? 12.176  13.054  52.879  1.00 45.54  ? 264 LYS A NZ  1 
ATOM   1812  N N   . GLU A 1 246 ? 11.459  8.194   55.510  1.00 37.95  ? 265 GLU A N   1 
ATOM   1813  C CA  . GLU A 1 246 ? 12.259  7.047   55.125  1.00 37.55  ? 265 GLU A CA  1 
ATOM   1814  C C   . GLU A 1 246 ? 12.120  5.919   56.134  1.00 35.81  ? 265 GLU A C   1 
ATOM   1815  O O   . GLU A 1 246 ? 12.078  4.738   55.757  1.00 35.27  ? 265 GLU A O   1 
ATOM   1816  C CB  . GLU A 1 246 ? 13.727  7.451   55.003  1.00 38.61  ? 265 GLU A CB  1 
ATOM   1817  C CG  . GLU A 1 246 ? 14.071  8.311   53.782  1.00 40.36  ? 265 GLU A CG  1 
ATOM   1818  C CD  . GLU A 1 246 ? 13.812  9.826   53.999  1.00 41.72  ? 265 GLU A CD  1 
ATOM   1819  O OE1 . GLU A 1 246 ? 13.541  10.238  55.140  1.00 41.27  ? 265 GLU A OE1 1 
ATOM   1820  O OE2 . GLU A 1 246 ? 13.863  10.592  53.015  1.00 43.38  ? 265 GLU A OE2 1 
ATOM   1821  N N   . THR A 1 247 ? 12.042  6.250   57.427  1.00 37.82  ? 266 THR A N   1 
ATOM   1822  C CA  . THR A 1 247 ? 11.993  5.171   58.413  1.00 36.46  ? 266 THR A CA  1 
ATOM   1823  C C   . THR A 1 247 ? 10.590  4.612   58.528  1.00 35.54  ? 266 THR A C   1 
ATOM   1824  O O   . THR A 1 247 ? 10.414  3.438   58.884  1.00 34.75  ? 266 THR A O   1 
ATOM   1825  C CB  . THR A 1 247 ? 12.484  5.621   59.809  1.00 36.66  ? 266 THR A CB  1 
ATOM   1826  O OG1 . THR A 1 247 ? 11.726  6.736   60.283  1.00 37.17  ? 266 THR A OG1 1 
ATOM   1827  C CG2 . THR A 1 247 ? 13.937  5.983   59.787  1.00 37.48  ? 266 THR A CG2 1 
ATOM   1828  N N   . MET A 1 248 ? 9.579   5.437   58.268  1.00 35.47  ? 267 MET A N   1 
ATOM   1829  C CA  . MET A 1 248 ? 8.210   4.934   58.362  1.00 34.83  ? 267 MET A CA  1 
ATOM   1830  C C   . MET A 1 248 ? 7.880   4.025   57.175  1.00 34.96  ? 267 MET A C   1 
ATOM   1831  O O   . MET A 1 248 ? 7.021   3.145   57.285  1.00 34.30  ? 267 MET A O   1 
ATOM   1832  C CB  . MET A 1 248 ? 7.233   6.105   58.428  1.00 35.82  ? 267 MET A CB  1 
ATOM   1833  C CG  . MET A 1 248 ? 7.198   6.832   59.780  1.00 36.09  ? 267 MET A CG  1 
ATOM   1834  S SD  . MET A 1 248 ? 5.939   8.118   59.656  1.00 37.31  ? 267 MET A SD  1 
ATOM   1835  C CE  . MET A 1 248 ? 6.629   9.194   58.468  1.00 38.92  ? 267 MET A CE  1 
ATOM   1836  N N   . LEU A 1 249 ? 8.530   4.243   56.033  1.00 36.04  ? 268 LEU A N   1 
ATOM   1837  C CA  . LEU A 1 249 ? 8.302   3.397   54.884  1.00 36.38  ? 268 LEU A CA  1 
ATOM   1838  C C   . LEU A 1 249 ? 8.994   2.053   55.090  1.00 35.36  ? 268 LEU A C   1 
ATOM   1839  O O   . LEU A 1 249 ? 8.423   1.005   54.752  1.00 35.19  ? 268 LEU A O   1 
ATOM   1840  C CB  . LEU A 1 249 ? 8.812   4.081   53.617  1.00 37.66  ? 268 LEU A CB  1 
ATOM   1841  C CG  . LEU A 1 249 ? 8.683   3.274   52.330  1.00 38.12  ? 268 LEU A CG  1 
ATOM   1842  C CD1 . LEU A 1 249 ? 7.276   2.826   52.301  1.00 37.87  ? 268 LEU A CD1 1 
ATOM   1843  C CD2 . LEU A 1 249 ? 9.011   4.021   51.053  1.00 39.56  ? 268 LEU A CD2 1 
ATOM   1844  N N   A ARG A 1 250 ? 10.214  2.071   55.646  0.55 35.94  ? 269 ARG A N   1 
ATOM   1845  N N   B ARG A 1 250 ? 10.220  2.074   55.629  0.45 35.95  ? 269 ARG A N   1 
ATOM   1846  C CA  A ARG A 1 250 ? 10.937  0.832   55.899  0.55 35.20  ? 269 ARG A CA  1 
ATOM   1847  C CA  B ARG A 1 250 ? 10.927  0.833   55.905  0.45 35.30  ? 269 ARG A CA  1 
ATOM   1848  C C   A ARG A 1 250 ? 10.156  -0.048  56.865  0.55 34.29  ? 269 ARG A C   1 
ATOM   1849  C C   B ARG A 1 250 ? 10.112  -0.043  56.841  0.45 34.30  ? 269 ARG A C   1 
ATOM   1850  O O   A ARG A 1 250 ? 10.034  -1.255  56.647  0.55 34.00  ? 269 ARG A O   1 
ATOM   1851  O O   B ARG A 1 250 ? 9.932   -1.237  56.587  0.45 33.99  ? 269 ARG A O   1 
ATOM   1852  C CB  A ARG A 1 250 ? 12.351  1.146   56.418  0.55 35.57  ? 269 ARG A CB  1 
ATOM   1853  C CB  B ARG A 1 250 ? 12.310  1.127   56.498  0.45 35.66  ? 269 ARG A CB  1 
ATOM   1854  C CG  A ARG A 1 250 ? 13.317  1.652   55.308  0.55 36.87  ? 269 ARG A CG  1 
ATOM   1855  C CG  B ARG A 1 250 ? 13.327  0.016   56.226  0.45 35.94  ? 269 ARG A CG  1 
ATOM   1856  C CD  A ARG A 1 250 ? 14.732  1.097   55.392  0.55 37.78  ? 269 ARG A CD  1 
ATOM   1857  C CD  B ARG A 1 250 ? 14.441  -0.042  57.243  0.45 36.39  ? 269 ARG A CD  1 
ATOM   1858  N NE  A ARG A 1 250 ? 15.330  1.370   56.686  0.55 37.54  ? 269 ARG A NE  1 
ATOM   1859  N NE  B ARG A 1 250 ? 14.066  -0.869  58.384  0.45 35.39  ? 269 ARG A NE  1 
ATOM   1860  C CZ  A ARG A 1 250 ? 15.681  2.576   57.106  0.55 38.12  ? 269 ARG A CZ  1 
ATOM   1861  C CZ  B ARG A 1 250 ? 13.917  -2.189  58.363  0.45 35.49  ? 269 ARG A CZ  1 
ATOM   1862  N NH1 A ARG A 1 250 ? 15.553  3.643   56.333  0.55 39.40  ? 269 ARG A NH1 1 
ATOM   1863  N NH1 B ARG A 1 250 ? 14.156  -2.903  57.269  0.45 36.12  ? 269 ARG A NH1 1 
ATOM   1864  N NH2 A ARG A 1 250 ? 16.156  2.716   58.338  0.55 37.25  ? 269 ARG A NH2 1 
ATOM   1865  N NH2 B ARG A 1 250 ? 13.510  -2.805  59.466  0.45 34.85  ? 269 ARG A NH2 1 
ATOM   1866  N N   . ASP A 1 251 ? 9.556   0.553   57.892  1.00 36.54  ? 270 ASP A N   1 
ATOM   1867  C CA  . ASP A 1 251 ? 8.767   -0.209  58.850  1.00 35.53  ? 270 ASP A CA  1 
ATOM   1868  C C   . ASP A 1 251 ? 7.483   -0.742  58.221  1.00 35.65  ? 270 ASP A C   1 
ATOM   1869  O O   . ASP A 1 251 ? 7.064   -1.861  58.495  1.00 35.13  ? 270 ASP A O   1 
ATOM   1870  C CB  . ASP A 1 251 ? 8.431   0.674   60.069  1.00 35.49  ? 270 ASP A CB  1 
ATOM   1871  C CG  . ASP A 1 251 ? 9.650   0.938   61.010  1.00 35.10  ? 270 ASP A CG  1 
ATOM   1872  O OD1 . ASP A 1 251 ? 10.704  0.295   60.862  1.00 35.53  ? 270 ASP A OD1 1 
ATOM   1873  O OD2 . ASP A 1 251 ? 9.581   1.788   61.940  1.00 34.61  ? 270 ASP A OD2 1 
ATOM   1874  N N   . ILE A 1 252 ? 6.814   0.047   57.402  1.00 33.47  ? 271 ILE A N   1 
ATOM   1875  C CA  . ILE A 1 252 ? 5.590   -0.452  56.778  1.00 33.88  ? 271 ILE A CA  1 
ATOM   1876  C C   . ILE A 1 252 ? 5.922   -1.573  55.808  1.00 34.56  ? 271 ILE A C   1 
ATOM   1877  O O   . ILE A 1 252 ? 5.237   -2.601  55.753  1.00 34.68  ? 271 ILE A O   1 
ATOM   1878  C CB  . ILE A 1 252 ? 4.844   0.690   56.077  1.00 34.74  ? 271 ILE A CB  1 
ATOM   1879  C CG1 . ILE A 1 252 ? 4.300   1.645   57.130  1.00 34.84  ? 271 ILE A CG1 1 
ATOM   1880  C CG2 . ILE A 1 252 ? 3.686   0.172   55.225  1.00 35.32  ? 271 ILE A CG2 1 
ATOM   1881  C CD1 . ILE A 1 252 ? 3.982   3.027   56.595  1.00 36.03  ? 271 ILE A CD1 1 
ATOM   1882  N N   . LEU A 1 253 ? 6.979   -1.394  55.026  1.00 34.26  ? 272 LEU A N   1 
ATOM   1883  C CA  . LEU A 1 253 ? 7.389   -2.465  54.140  1.00 34.40  ? 272 LEU A CA  1 
ATOM   1884  C C   . LEU A 1 253 ? 7.789   -3.689  54.938  1.00 33.57  ? 272 LEU A C   1 
ATOM   1885  O O   . LEU A 1 253 ? 7.442   -4.820  54.584  1.00 33.94  ? 272 LEU A O   1 
ATOM   1886  C CB  . LEU A 1 253 ? 8.535   -2.004  53.262  1.00 35.24  ? 272 LEU A CB  1 
ATOM   1887  C CG  . LEU A 1 253 ? 8.139   -1.007  52.168  1.00 36.42  ? 272 LEU A CG  1 
ATOM   1888  C CD1 . LEU A 1 253 ? 9.431   -0.640  51.396  1.00 37.16  ? 272 LEU A CD1 1 
ATOM   1889  C CD2 . LEU A 1 253 ? 6.995   -1.553  51.280  1.00 37.04  ? 272 LEU A CD2 1 
ATOM   1890  N N   . GLU A 1 254 ? 8.516   -3.502  56.028  1.00 34.01  ? 273 GLU A N   1 
ATOM   1891  C CA  . GLU A 1 254 ? 8.930   -4.686  56.753  1.00 33.62  ? 273 GLU A CA  1 
ATOM   1892  C C   . GLU A 1 254 ? 7.712   -5.397  57.347  1.00 33.28  ? 273 GLU A C   1 
ATOM   1893  O O   . GLU A 1 254 ? 7.622   -6.625  57.281  1.00 33.51  ? 273 GLU A O   1 
ATOM   1894  C CB  . GLU A 1 254 ? 9.983   -4.322  57.785  1.00 33.28  ? 273 GLU A CB  1 
ATOM   1895  C CG  . GLU A 1 254 ? 10.450  -5.543  58.555  1.00 33.03  ? 273 GLU A CG  1 
ATOM   1896  C CD  . GLU A 1 254 ? 11.033  -6.663  57.688  1.00 34.33  ? 273 GLU A CD  1 
ATOM   1897  O OE1 . GLU A 1 254 ? 11.243  -6.470  56.467  1.00 35.05  ? 273 GLU A OE1 1 
ATOM   1898  O OE2 . GLU A 1 254 ? 11.287  -7.750  58.252  1.00 34.58  ? 273 GLU A OE2 1 
ATOM   1899  N N   . MET A 1 255 ? 6.726   -4.660  57.854  1.00 31.99  ? 274 MET A N   1 
ATOM   1900  C CA  . MET A 1 255 ? 5.518   -5.343  58.300  1.00 32.16  ? 274 MET A CA  1 
ATOM   1901  C C   . MET A 1 255 ? 4.929   -6.183  57.167  1.00 33.03  ? 274 MET A C   1 
ATOM   1902  O O   . MET A 1 255 ? 4.560   -7.339  57.362  1.00 33.52  ? 274 MET A O   1 
ATOM   1903  C CB  . MET A 1 255 ? 4.476   -4.351  58.790  1.00 32.20  ? 274 MET A CB  1 
ATOM   1904  C CG  . MET A 1 255 ? 3.164   -5.015  59.231  1.00 32.46  ? 274 MET A CG  1 
ATOM   1905  S SD  . MET A 1 255 ? 1.905   -3.900  59.938  1.00 32.77  ? 274 MET A SD  1 
ATOM   1906  C CE  . MET A 1 255 ? 1.804   -2.633  58.634  1.00 33.58  ? 274 MET A CE  1 
ATOM   1907  N N   . GLN A 1 256 ? 4.810   -5.587  55.972  1.00 32.93  ? 275 GLN A N   1 
ATOM   1908  C CA  . GLN A 1 256 ? 4.202   -6.258  54.833  1.00 34.19  ? 275 GLN A CA  1 
ATOM   1909  C C   . GLN A 1 256 ? 4.953   -7.529  54.505  1.00 34.50  ? 275 GLN A C   1 
ATOM   1910  O O   . GLN A 1 256 ? 4.346   -8.553  54.161  1.00 35.54  ? 275 GLN A O   1 
ATOM   1911  C CB  . GLN A 1 256 ? 4.193   -5.294  53.644  1.00 35.13  ? 275 GLN A CB  1 
ATOM   1912  C CG  . GLN A 1 256 ? 3.599   -5.809  52.322  1.00 36.11  ? 275 GLN A CG  1 
ATOM   1913  C CD  . GLN A 1 256 ? 3.624   -4.739  51.191  1.00 37.09  ? 275 GLN A CD  1 
ATOM   1914  O OE1 . GLN A 1 256 ? 2.577   -4.320  50.694  1.00 37.57  ? 275 GLN A OE1 1 
ATOM   1915  N NE2 . GLN A 1 256 ? 4.813   -4.325  50.787  1.00 37.23  ? 275 GLN A NE2 1 
ATOM   1916  N N   . ARG A 1 257 ? 6.278   -7.477  54.605  1.00 33.06  ? 276 ARG A N   1 
ATOM   1917  C CA  . ARG A 1 257 ? 7.090   -8.589  54.143  1.00 33.54  ? 276 ARG A CA  1 
ATOM   1918  C C   . ARG A 1 257 ? 7.162   -9.696  55.194  1.00 33.24  ? 276 ARG A C   1 
ATOM   1919  O O   . ARG A 1 257 ? 7.120   -10.892 54.862  1.00 34.10  ? 276 ARG A O   1 
ATOM   1920  C CB  . ARG A 1 257 ? 8.479   -8.082  53.800  1.00 33.76  ? 276 ARG A CB  1 
ATOM   1921  C CG  . ARG A 1 257 ? 9.348   -9.082  53.105  1.00 34.68  ? 276 ARG A CG  1 
ATOM   1922  C CD  . ARG A 1 257 ? 10.803  -8.783  53.352  1.00 34.99  ? 276 ARG A CD  1 
ATOM   1923  N NE  . ARG A 1 257 ? 11.056  -8.896  54.781  1.00 34.31  ? 276 ARG A NE  1 
ATOM   1924  C CZ  . ARG A 1 257 ? 11.083  -10.043 55.444  1.00 34.43  ? 276 ARG A CZ  1 
ATOM   1925  N NH1 . ARG A 1 257 ? 11.056  -11.205 54.806  1.00 35.79  ? 276 ARG A NH1 1 
ATOM   1926  N NH2 . ARG A 1 257 ? 11.126  -10.023 56.777  1.00 33.71  ? 276 ARG A NH2 1 
ATOM   1927  N N   . ALA A 1 258 ? 7.264   -9.323  56.463  1.00 33.44  ? 277 ALA A N   1 
ATOM   1928  C CA  . ALA A 1 258 ? 7.324   -10.348 57.487  1.00 33.15  ? 277 ALA A CA  1 
ATOM   1929  C C   . ALA A 1 258 ? 5.984   -11.061 57.586  1.00 33.59  ? 277 ALA A C   1 
ATOM   1930  O O   . ALA A 1 258 ? 5.924   -12.290 57.758  1.00 34.28  ? 277 ALA A O   1 
ATOM   1931  C CB  . ALA A 1 258 ? 7.732   -9.746  58.827  1.00 31.94  ? 277 ALA A CB  1 
ATOM   1932  N N   . ALA A 1 259 ? 4.889   -10.309 57.466  1.00 31.01  ? 278 ALA A N   1 
ATOM   1933  C CA  . ALA A 1 259 ? 3.581   -10.942 57.575  1.00 32.23  ? 278 ALA A CA  1 
ATOM   1934  C C   . ALA A 1 259 ? 3.301   -11.810 56.342  1.00 33.97  ? 278 ALA A C   1 
ATOM   1935  O O   . ALA A 1 259 ? 2.856   -12.956 56.455  1.00 35.31  ? 278 ALA A O   1 
ATOM   1936  C CB  . ALA A 1 259 ? 2.503   -9.891  57.814  1.00 32.26  ? 278 ALA A CB  1 
ATOM   1937  N N   . LYS A 1 260 ? 3.651   -11.323 55.171  1.00 33.44  ? 279 LYS A N   1 
ATOM   1938  C CA  . LYS A 1 260 ? 3.486   -12.151 53.993  1.00 35.02  ? 279 LYS A CA  1 
ATOM   1939  C C   . LYS A 1 260 ? 4.278   -13.428 54.117  1.00 35.63  ? 279 LYS A C   1 
ATOM   1940  O O   . LYS A 1 260 ? 3.937   -14.436 53.494  1.00 37.23  ? 279 LYS A O   1 
ATOM   1941  C CB  . LYS A 1 260 ? 3.896   -11.377 52.754  1.00 35.87  ? 279 LYS A CB  1 
ATOM   1942  C CG  . LYS A 1 260 ? 2.678   -10.724 52.165  1.00 36.97  ? 279 LYS A CG  1 
ATOM   1943  C CD  . LYS A 1 260 ? 3.003   -9.452  51.442  1.00 36.99  ? 279 LYS A CD  1 
ATOM   1944  C CE  . LYS A 1 260 ? 1.961   -9.151  50.350  1.00 39.22  ? 279 LYS A CE  1 
ATOM   1945  N NZ  . LYS A 1 260 ? 2.657   -8.414  49.209  1.00 40.02  ? 279 LYS A NZ  1 
ATOM   1946  N N   . ALA A 1 261 ? 5.334   -13.408 54.907  1.00 34.31  ? 280 ALA A N   1 
ATOM   1947  C CA  . ALA A 1 261 ? 6.133   -14.604 55.096  1.00 34.82  ? 280 ALA A CA  1 
ATOM   1948  C C   . ALA A 1 261 ? 5.640   -15.429 56.271  1.00 34.92  ? 280 ALA A C   1 
ATOM   1949  O O   . ALA A 1 261 ? 6.318   -16.364 56.670  1.00 35.70  ? 280 ALA A O   1 
ATOM   1950  C CB  . ALA A 1 261 ? 7.604   -14.243 55.275  1.00 34.36  ? 280 ALA A CB  1 
ATOM   1951  N N   . GLY A 1 262 ? 4.475   -15.108 56.838  1.00 33.28  ? 281 GLY A N   1 
ATOM   1952  C CA  . GLY A 1 262 ? 3.863   -15.961 57.835  1.00 33.32  ? 281 GLY A CA  1 
ATOM   1953  C C   . GLY A 1 262 ? 4.028   -15.537 59.283  1.00 31.59  ? 281 GLY A C   1 
ATOM   1954  O O   . GLY A 1 262 ? 3.509   -16.229 60.175  1.00 32.38  ? 281 GLY A O   1 
ATOM   1955  N N   . LYS A 1 263 ? 4.705   -14.421 59.558  1.00 32.78  ? 282 LYS A N   1 
ATOM   1956  C CA  . LYS A 1 263 ? 4.942   -14.002 60.929  1.00 30.81  ? 282 LYS A CA  1 
ATOM   1957  C C   . LYS A 1 263 ? 3.808   -13.132 61.433  1.00 30.64  ? 282 LYS A C   1 
ATOM   1958  O O   . LYS A 1 263 ? 2.932   -12.722 60.690  1.00 32.04  ? 282 LYS A O   1 
ATOM   1959  C CB  . LYS A 1 263 ? 6.261   -13.251 61.035  1.00 29.69  ? 282 LYS A CB  1 
ATOM   1960  C CG  . LYS A 1 263 ? 7.481   -14.077 60.708  1.00 30.83  ? 282 LYS A CG  1 
ATOM   1961  C CD  . LYS A 1 263 ? 7.570   -15.318 61.570  1.00 30.83  ? 282 LYS A CD  1 
ATOM   1962  C CE  . LYS A 1 263 ? 8.917   -16.051 61.352  1.00 31.43  ? 282 LYS A CE  1 
ATOM   1963  N NZ  . LYS A 1 263 ? 8.990   -17.332 62.120  1.00 32.12  ? 282 LYS A NZ  1 
ATOM   1964  N N   . ILE A 1 264 ? 3.830   -12.893 62.741  1.00 30.11  ? 283 ILE A N   1 
ATOM   1965  C CA  . ILE A 1 264 ? 2.975   -11.916 63.402  1.00 29.19  ? 283 ILE A CA  1 
ATOM   1966  C C   . ILE A 1 264 ? 3.761   -10.609 63.551  1.00 27.89  ? 283 ILE A C   1 
ATOM   1967  O O   . ILE A 1 264 ? 4.954   -10.630 63.864  1.00 27.28  ? 283 ILE A O   1 
ATOM   1968  C CB  . ILE A 1 264 ? 2.507   -12.428 64.763  1.00 27.94  ? 283 ILE A CB  1 
ATOM   1969  C CG1 . ILE A 1 264 ? 1.587   -13.634 64.617  1.00 29.52  ? 283 ILE A CG1 1 
ATOM   1970  C CG2 . ILE A 1 264 ? 1.815   -11.317 65.489  1.00 26.99  ? 283 ILE A CG2 1 
ATOM   1971  C CD1 . ILE A 1 264 ? 1.465   -14.476 65.888  1.00 28.44  ? 283 ILE A CD1 1 
ATOM   1972  N N   . VAL A 1 265 ? 3.120   -9.488  63.224  1.00 28.01  ? 284 VAL A N   1 
ATOM   1973  C CA  . VAL A 1 265 ? 3.722   -8.160  63.353  1.00 27.22  ? 284 VAL A CA  1 
ATOM   1974  C C   . VAL A 1 265 ? 2.786   -7.314  64.196  1.00 26.72  ? 284 VAL A C   1 
ATOM   1975  O O   . VAL A 1 265 ? 1.582   -7.316  63.972  1.00 27.50  ? 284 VAL A O   1 
ATOM   1976  C CB  . VAL A 1 265 ? 3.991   -7.487  61.999  1.00 28.69  ? 284 VAL A CB  1 
ATOM   1977  C CG1 . VAL A 1 265 ? 4.685   -6.142  62.198  1.00 28.15  ? 284 VAL A CG1 1 
ATOM   1978  C CG2 . VAL A 1 265 ? 4.847   -8.399  61.102  1.00 29.73  ? 284 VAL A CG2 1 
ATOM   1979  N N   . VAL A 1 266 ? 3.329   -6.657  65.214  1.00 28.75  ? 285 VAL A N   1 
ATOM   1980  C CA  . VAL A 1 266 ? 2.578   -5.749  66.060  1.00 28.09  ? 285 VAL A CA  1 
ATOM   1981  C C   . VAL A 1 266 ? 3.161   -4.368  65.852  1.00 28.30  ? 285 VAL A C   1 
ATOM   1982  O O   . VAL A 1 266 ? 4.341   -4.145  66.131  1.00 27.85  ? 285 VAL A O   1 
ATOM   1983  C CB  . VAL A 1 266 ? 2.636   -6.158  67.537  1.00 26.87  ? 285 VAL A CB  1 
ATOM   1984  C CG1 . VAL A 1 266 ? 1.896   -5.098  68.418  1.00 26.51  ? 285 VAL A CG1 1 
ATOM   1985  C CG2 . VAL A 1 266 ? 2.035   -7.568  67.692  1.00 26.91  ? 285 VAL A CG2 1 
ATOM   1986  N N   . LEU A 1 267 ? 2.362   -3.459  65.304  1.00 27.76  ? 286 LEU A N   1 
ATOM   1987  C CA  . LEU A 1 267 ? 2.778   -2.066  65.118  1.00 28.25  ? 286 LEU A CA  1 
ATOM   1988  C C   . LEU A 1 267 ? 2.222   -1.215  66.250  1.00 27.74  ? 286 LEU A C   1 
ATOM   1989  O O   . LEU A 1 267 ? 0.998   -1.203  66.476  1.00 28.07  ? 286 LEU A O   1 
ATOM   1990  C CB  . LEU A 1 267 ? 2.295   -1.526  63.786  1.00 29.86  ? 286 LEU A CB  1 
ATOM   1991  C CG  . LEU A 1 267 ? 2.776   -0.167  63.298  1.00 30.62  ? 286 LEU A CG  1 
ATOM   1992  C CD1 . LEU A 1 267 ? 2.870   -0.244  61.775  1.00 32.08  ? 286 LEU A CD1 1 
ATOM   1993  C CD2 . LEU A 1 267 ? 1.824   0.932   63.710  1.00 31.28  ? 286 LEU A CD2 1 
ATOM   1994  N N   . LYS A 1 268 ? 3.123   -0.558  66.987  1.00 28.13  ? 287 LYS A N   1 
ATOM   1995  C CA  . LYS A 1 268 ? 2.747   0.305   68.112  1.00 28.08  ? 287 LYS A CA  1 
ATOM   1996  C C   . LYS A 1 268 ? 2.537   1.728   67.601  1.00 29.92  ? 287 LYS A C   1 
ATOM   1997  O O   . LYS A 1 268 ? 3.492   2.405   67.233  1.00 30.70  ? 287 LYS A O   1 
ATOM   1998  C CB  . LYS A 1 268 ? 3.829   0.258   69.195  1.00 27.53  ? 287 LYS A CB  1 
ATOM   1999  C CG  . LYS A 1 268 ? 3.569   1.144   70.388  1.00 29.55  ? 287 LYS A CG  1 
ATOM   2000  C CD  . LYS A 1 268 ? 2.294   0.710   71.095  1.00 28.04  ? 287 LYS A CD  1 
ATOM   2001  C CE  . LYS A 1 268 ? 2.231   1.285   72.515  1.00 29.64  ? 287 LYS A CE  1 
ATOM   2002  N NZ  . LYS A 1 268 ? 1.729   2.648   72.523  1.00 29.59  ? 287 LYS A NZ  1 
ATOM   2003  N N   . GLY A 1 269 ? 1.281   2.169   67.518  1.00 28.12  ? 288 GLY A N   1 
ATOM   2004  C CA  . GLY A 1 269 ? 0.978   3.567   67.209  1.00 29.17  ? 288 GLY A CA  1 
ATOM   2005  C C   . GLY A 1 269 ? 0.978   4.426   68.468  1.00 29.18  ? 288 GLY A C   1 
ATOM   2006  O O   . GLY A 1 269 ? 0.471   4.008   69.512  1.00 28.62  ? 288 GLY A O   1 
ATOM   2007  N N   . TRP A 1 270 ? 1.542   5.620   68.359  1.00 30.36  ? 289 TRP A N   1 
ATOM   2008  C CA  . TRP A 1 270 ? 1.569   6.554   69.485  1.00 31.01  ? 289 TRP A CA  1 
ATOM   2009  C C   . TRP A 1 270 ? 0.559   7.654   69.247  1.00 32.21  ? 289 TRP A C   1 
ATOM   2010  O O   . TRP A 1 270 ? 0.422   8.134   68.127  1.00 33.58  ? 289 TRP A O   1 
ATOM   2011  C CB  . TRP A 1 270 ? 2.962   7.131   69.691  1.00 31.98  ? 289 TRP A CB  1 
ATOM   2012  C CG  . TRP A 1 270 ? 3.927   6.079   70.060  1.00 30.77  ? 289 TRP A CG  1 
ATOM   2013  C CD1 . TRP A 1 270 ? 4.690   5.338   69.204  1.00 29.92  ? 289 TRP A CD1 1 
ATOM   2014  C CD2 . TRP A 1 270 ? 4.228   5.602   71.377  1.00 30.04  ? 289 TRP A CD2 1 
ATOM   2015  N NE1 . TRP A 1 270 ? 5.458   4.439   69.904  1.00 29.06  ? 289 TRP A NE1 1 
ATOM   2016  C CE2 . TRP A 1 270 ? 5.200   4.589   71.240  1.00 29.31  ? 289 TRP A CE2 1 
ATOM   2017  C CE3 . TRP A 1 270 ? 3.804   5.960   72.655  1.00 30.47  ? 289 TRP A CE3 1 
ATOM   2018  C CZ2 . TRP A 1 270 ? 5.755   3.923   72.334  1.00 28.87  ? 289 TRP A CZ2 1 
ATOM   2019  C CZ3 . TRP A 1 270 ? 4.348   5.264   73.762  1.00 30.16  ? 289 TRP A CZ3 1 
ATOM   2020  C CH2 . TRP A 1 270 ? 5.317   4.262   73.582  1.00 29.40  ? 289 TRP A CH2 1 
ATOM   2021  N N   . ALA A 1 271 ? -0.140  8.032   70.313  1.00 27.66  ? 290 ALA A N   1 
ATOM   2022  C CA  . ALA A 1 271 ? -1.352  8.846   70.244  1.00 29.23  ? 290 ALA A CA  1 
ATOM   2023  C C   . ALA A 1 271 ? -1.050  10.349  70.321  1.00 30.80  ? 290 ALA A C   1 
ATOM   2024  O O   . ALA A 1 271 ? -1.646  11.114  71.082  1.00 31.66  ? 290 ALA A O   1 
ATOM   2025  C CB  . ALA A 1 271 ? -2.314  8.404   71.338  1.00 29.04  ? 290 ALA A CB  1 
ATOM   2026  N N   . GLY A 1 272 ? -0.121  10.768  69.480  1.00 30.37  ? 291 GLY A N   1 
ATOM   2027  C CA  . GLY A 1 272 ? 0.193   12.156  69.354  1.00 31.92  ? 291 GLY A CA  1 
ATOM   2028  C C   . GLY A 1 272 ? 1.221   12.655  70.329  1.00 32.08  ? 291 GLY A C   1 
ATOM   2029  O O   . GLY A 1 272 ? 1.638   13.823  70.224  1.00 33.83  ? 291 GLY A O   1 
ATOM   2030  N N   . PHE A 1 273 ? 1.618   11.814  71.258  1.00 30.67  ? 292 PHE A N   1 
ATOM   2031  C CA  . PHE A 1 273 ? 2.674   12.065  72.211  1.00 30.78  ? 292 PHE A CA  1 
ATOM   2032  C C   . PHE A 1 273 ? 3.020   10.722  72.852  1.00 29.38  ? 292 PHE A C   1 
ATOM   2033  O O   . PHE A 1 273 ? 2.442   9.668   72.532  1.00 28.18  ? 292 PHE A O   1 
ATOM   2034  C CB  . PHE A 1 273 ? 2.254   13.089  73.257  1.00 31.71  ? 292 PHE A CB  1 
ATOM   2035  C CG  . PHE A 1 273 ? 1.079   12.675  74.084  1.00 31.11  ? 292 PHE A CG  1 
ATOM   2036  C CD1 . PHE A 1 273 ? -0.170  12.740  73.587  1.00 31.18  ? 292 PHE A CD1 1 
ATOM   2037  C CD2 . PHE A 1 273 ? 1.232   12.279  75.392  1.00 30.75  ? 292 PHE A CD2 1 
ATOM   2038  C CE1 . PHE A 1 273 ? -1.242  12.393  74.364  1.00 31.19  ? 292 PHE A CE1 1 
ATOM   2039  C CE2 . PHE A 1 273 ? 0.145   11.941  76.166  1.00 30.69  ? 292 PHE A CE2 1 
ATOM   2040  C CZ  . PHE A 1 273 ? -1.077  11.993  75.651  1.00 30.89  ? 292 PHE A CZ  1 
ATOM   2041  N N   . THR A 1 274 ? 3.971   10.771  73.778  1.00 31.56  ? 293 THR A N   1 
ATOM   2042  C CA  . THR A 1 274 ? 4.403   9.596   74.489  1.00 30.64  ? 293 THR A CA  1 
ATOM   2043  C C   . THR A 1 274 ? 4.608   9.942   75.945  1.00 31.28  ? 293 THR A C   1 
ATOM   2044  O O   . THR A 1 274 ? 4.642   11.109  76.342  1.00 32.54  ? 293 THR A O   1 
ATOM   2045  C CB  . THR A 1 274 ? 5.705   9.026   73.965  1.00 30.35  ? 293 THR A CB  1 
ATOM   2046  O OG1 . THR A 1 274 ? 6.774   9.680   74.631  1.00 31.29  ? 293 THR A OG1 1 
ATOM   2047  C CG2 . THR A 1 274 ? 5.848   9.217   72.491  1.00 30.45  ? 293 THR A CG2 1 
ATOM   2048  N N   . PHE A 1 275 ? 4.746   8.887   76.741  1.00 31.25  ? 294 PHE A N   1 
ATOM   2049  C CA  . PHE A 1 275 ? 4.965   8.990   78.180  1.00 32.08  ? 294 PHE A CA  1 
ATOM   2050  C C   . PHE A 1 275 ? 6.322   9.569   78.531  1.00 32.84  ? 294 PHE A C   1 
ATOM   2051  O O   . PHE A 1 275 ? 6.562   9.819   79.716  1.00 34.12  ? 294 PHE A O   1 
ATOM   2052  C CB  . PHE A 1 275 ? 4.837   7.592   78.823  1.00 31.31  ? 294 PHE A CB  1 
ATOM   2053  C CG  . PHE A 1 275 ? 5.961   6.682   78.498  1.00 30.45  ? 294 PHE A CG  1 
ATOM   2054  C CD1 . PHE A 1 275 ? 5.967   6.000   77.292  1.00 29.63  ? 294 PHE A CD1 1 
ATOM   2055  C CD2 . PHE A 1 275 ? 7.001   6.498   79.376  1.00 31.23  ? 294 PHE A CD2 1 
ATOM   2056  C CE1 . PHE A 1 275 ? 6.991   5.127   76.955  1.00 28.88  ? 294 PHE A CE1 1 
ATOM   2057  C CE2 . PHE A 1 275 ? 8.049   5.637   79.051  1.00 30.53  ? 294 PHE A CE2 1 
ATOM   2058  C CZ  . PHE A 1 275 ? 8.043   4.948   77.837  1.00 29.35  ? 294 PHE A CZ  1 
ATOM   2059  N N   . ILE A 1 276 ? 7.225   9.711   77.552  1.00 33.51  ? 295 ILE A N   1 
ATOM   2060  C CA  . ILE A 1 276 ? 8.610   10.216  77.805  1.00 34.43  ? 295 ILE A CA  1 
ATOM   2061  C C   . ILE A 1 276 ? 8.596   11.743  77.643  1.00 35.51  ? 295 ILE A C   1 
ATOM   2062  O O   . ILE A 1 276 ? 9.488   12.398  78.220  1.00 36.71  ? 295 ILE A O   1 
ATOM   2063  C CB  . ILE A 1 276 ? 9.651   9.534   76.891  1.00 34.16  ? 295 ILE A CB  1 
ATOM   2064  C CG1 . ILE A 1 276 ? 9.961   10.347  75.623  1.00 34.01  ? 295 ILE A CG1 1 
ATOM   2065  C CG2 . ILE A 1 276 ? 9.224   8.103   76.559  1.00 32.71  ? 295 ILE A CG2 1 
ATOM   2066  C CD1 . ILE A 1 276 ? 11.058  9.752   74.760  1.00 34.02  ? 295 ILE A CD1 1 
ATOM   2067  N N   . ASP A 1 277 ? 7.632   12.284  76.895  1.00 37.21  ? 296 ASP A N   1 
ATOM   2068  C CA  . ASP A 1 277 ? 7.492   13.757  76.743  1.00 38.62  ? 296 ASP A CA  1 
ATOM   2069  C C   . ASP A 1 277 ? 6.956   14.289  78.072  1.00 39.12  ? 296 ASP A C   1 
ATOM   2070  O O   . ASP A 1 277 ? 5.807   13.966  78.397  1.00 38.80  ? 296 ASP A O   1 
ATOM   2071  C CB  . ASP A 1 277 ? 6.624   14.113  75.547  1.00 38.77  ? 296 ASP A CB  1 
ATOM   2072  C CG  . ASP A 1 277 ? 6.551   15.594  75.203  1.00 40.53  ? 296 ASP A CG  1 
ATOM   2073  O OD1 . ASP A 1 277 ? 7.164   16.401  75.932  1.00 42.90  ? 296 ASP A OD1 1 
ATOM   2074  O OD2 . ASP A 1 277 ? 5.892   15.928  74.198  1.00 39.61  ? 296 ASP A OD2 1 
ATOM   2075  N N   . ASP A 1 278 ? 7.755   15.060  78.811  1.00 39.20  ? 297 ASP A N   1 
ATOM   2076  C CA  . ASP A 1 278 ? 7.357   15.537  80.164  1.00 39.92  ? 297 ASP A CA  1 
ATOM   2077  C C   . ASP A 1 278 ? 6.235   16.573  80.046  1.00 40.80  ? 297 ASP A C   1 
ATOM   2078  O O   . ASP A 1 278 ? 5.309   16.517  80.881  1.00 41.11  ? 297 ASP A O   1 
ATOM   2079  C CB  . ASP A 1 278 ? 8.556   16.073  80.930  1.00 41.34  ? 297 ASP A CB  1 
ATOM   2080  N N   . GLN A 1 279 ? 6.294   17.474  79.059  1.00 39.01  ? 298 GLN A N   1 
ATOM   2081  C CA  . GLN A 1 279 ? 5.293   18.536  78.937  1.00 39.73  ? 298 GLN A CA  1 
ATOM   2082  C C   . GLN A 1 279 ? 3.971   17.956  78.474  1.00 38.35  ? 298 GLN A C   1 
ATOM   2083  O O   . GLN A 1 279 ? 2.905   18.302  78.986  1.00 38.61  ? 298 GLN A O   1 
ATOM   2084  C CB  . GLN A 1 279 ? 5.771   19.651  77.986  1.00 41.21  ? 298 GLN A CB  1 
ATOM   2085  N N   . ALA A 1 280 ? 4.020   17.022  77.543  1.00 38.15  ? 299 ALA A N   1 
ATOM   2086  C CA  . ALA A 1 280 ? 2.778   16.407  77.083  1.00 37.21  ? 299 ALA A CA  1 
ATOM   2087  C C   . ALA A 1 280 ? 2.083   15.639  78.200  1.00 36.46  ? 299 ALA A C   1 
ATOM   2088  O O   . ALA A 1 280 ? 0.854   15.678  78.331  1.00 36.46  ? 299 ALA A O   1 
ATOM   2089  C CB  . ALA A 1 280 ? 3.070   15.478  75.913  1.00 36.09  ? 299 ALA A CB  1 
ATOM   2090  N N   . MET A 1 281 ? 2.852   14.937  79.029  1.00 36.81  ? 300 MET A N   1 
ATOM   2091  C CA  . MET A 1 281 ? 2.229   14.189  80.114  1.00 36.84  ? 300 MET A CA  1 
ATOM   2092  C C   . MET A 1 281 ? 1.622   15.072  81.207  1.00 37.77  ? 300 MET A C   1 
ATOM   2093  O O   . MET A 1 281 ? 0.785   14.561  81.961  1.00 38.24  ? 300 MET A O   1 
ATOM   2094  C CB  . MET A 1 281 ? 3.254   13.226  80.672  1.00 36.42  ? 300 MET A CB  1 
ATOM   2095  C CG  . MET A 1 281 ? 3.610   12.123  79.657  1.00 35.32  ? 300 MET A CG  1 
ATOM   2096  S SD  . MET A 1 281 ? 2.185   11.007  79.283  1.00 34.32  ? 300 MET A SD  1 
ATOM   2097  C CE  . MET A 1 281 ? 1.988   10.320  80.897  1.00 35.10  ? 300 MET A CE  1 
ATOM   2098  N N   . ARG A 1 282 ? 1.965   16.385  81.301  1.00 41.43  ? 301 ARG A N   1 
ATOM   2099  C CA  . ARG A 1 282 ? 1.314   17.266  82.278  1.00 42.95  ? 301 ARG A CA  1 
ATOM   2100  C C   . ARG A 1 282 ? -0.034  17.836  81.828  1.00 43.07  ? 301 ARG A C   1 
ATOM   2101  O O   . ARG A 1 282 ? -0.787  18.344  82.669  1.00 44.19  ? 301 ARG A O   1 
ATOM   2102  C CB  . ARG A 1 282 ? 2.226   18.427  82.645  1.00 44.50  ? 301 ARG A CB  1 
ATOM   2103  C CG  . ARG A 1 282 ? 3.411   18.003  83.435  1.00 45.32  ? 301 ARG A CG  1 
ATOM   2104  C CD  . ARG A 1 282 ? 4.435   19.118  83.670  1.00 47.02  ? 301 ARG A CD  1 
ATOM   2105  N NE  . ARG A 1 282 ? 5.663   18.505  84.184  1.00 47.41  ? 301 ARG A NE  1 
ATOM   2106  C CZ  . ARG A 1 282 ? 5.814   17.984  85.405  1.00 48.41  ? 301 ARG A CZ  1 
ATOM   2107  N NH1 . ARG A 1 282 ? 4.870   18.099  86.339  1.00 49.16  ? 301 ARG A NH1 1 
ATOM   2108  N NH2 . ARG A 1 282 ? 6.956   17.360  85.714  1.00 48.75  ? 301 ARG A NH2 1 
ATOM   2109  N N   . LYS A 1 283 ? -0.366  17.725  80.546  1.00 36.18  ? 302 LYS A N   1 
ATOM   2110  C CA  . LYS A 1 283 ? -1.656  18.179  80.047  1.00 36.37  ? 302 LYS A CA  1 
ATOM   2111  C C   . LYS A 1 283 ? -2.822  17.508  80.770  1.00 36.35  ? 302 LYS A C   1 
ATOM   2112  O O   . LYS A 1 283 ? -2.742  16.327  81.150  1.00 35.43  ? 302 LYS A O   1 
ATOM   2113  C CB  . LYS A 1 283 ? -1.742  17.902  78.542  1.00 36.02  ? 302 LYS A CB  1 
ATOM   2114  C CG  . LYS A 1 283 ? -0.684  18.637  77.707  1.00 37.72  ? 302 LYS A CG  1 
ATOM   2115  C CD  . LYS A 1 283 ? -0.468  20.117  78.162  1.00 40.36  ? 302 LYS A CD  1 
ATOM   2116  C CE  . LYS A 1 283 ? 0.369   20.827  77.107  1.00 41.92  ? 302 LYS A CE  1 
ATOM   2117  N NZ  . LYS A 1 283 ? 0.898   22.175  77.430  1.00 43.93  ? 302 LYS A NZ  1 
ATOM   2118  N N   . PRO A 1 284 ? -3.955  18.212  80.902  1.00 36.34  ? 303 PRO A N   1 
ATOM   2119  C CA  . PRO A 1 284 ? -5.172  17.573  81.419  1.00 36.44  ? 303 PRO A CA  1 
ATOM   2120  C C   . PRO A 1 284 ? -5.579  16.396  80.556  1.00 34.42  ? 303 PRO A C   1 
ATOM   2121  O O   . PRO A 1 284 ? -5.315  16.350  79.352  1.00 33.26  ? 303 PRO A O   1 
ATOM   2122  C CB  . PRO A 1 284 ? -6.231  18.670  81.326  1.00 37.89  ? 303 PRO A CB  1 
ATOM   2123  C CG  . PRO A 1 284 ? -5.481  19.931  81.122  1.00 39.18  ? 303 PRO A CG  1 
ATOM   2124  C CD  . PRO A 1 284 ? -4.276  19.533  80.318  1.00 37.67  ? 303 PRO A CD  1 
ATOM   2125  N N   . LEU A 1 285 ? -6.296  15.459  81.179  1.00 36.40  ? 304 LEU A N   1 
ATOM   2126  C CA  . LEU A 1 285 ? -6.665  14.244  80.472  1.00 35.23  ? 304 LEU A CA  1 
ATOM   2127  C C   . LEU A 1 285 ? -7.603  14.528  79.297  1.00 35.20  ? 304 LEU A C   1 
ATOM   2128  O O   . LEU A 1 285 ? -7.506  13.841  78.264  1.00 34.39  ? 304 LEU A O   1 
ATOM   2129  C CB  . LEU A 1 285 ? -7.283  13.247  81.444  1.00 35.11  ? 304 LEU A CB  1 
ATOM   2130  C CG  . LEU A 1 285 ? -7.657  11.886  80.819  1.00 34.16  ? 304 LEU A CG  1 
ATOM   2131  C CD1 . LEU A 1 285 ? -6.536  11.224  80.083  1.00 33.29  ? 304 LEU A CD1 1 
ATOM   2132  C CD2 . LEU A 1 285 ? -8.148  10.980  81.906  1.00 34.08  ? 304 LEU A CD2 1 
ATOM   2133  N N   . THR A 1 286 ? -8.481  15.550  79.385  1.00 36.25  ? 305 THR A N   1 
ATOM   2134  C CA  . THR A 1 286 ? -9.321  15.806  78.205  1.00 36.52  ? 305 THR A CA  1 
ATOM   2135  C C   . THR A 1 286 ? -8.459  16.265  77.042  1.00 36.38  ? 305 THR A C   1 
ATOM   2136  O O   . THR A 1 286 ? -8.730  15.915  75.891  1.00 36.60  ? 305 THR A O   1 
ATOM   2137  C CB  . THR A 1 286 ? -10.464 16.788  78.469  1.00 38.35  ? 305 THR A CB  1 
ATOM   2138  O OG1 . THR A 1 286 ? -10.007 18.131  78.535  1.00 39.73  ? 305 THR A OG1 1 
ATOM   2139  C CG2 . THR A 1 286 ? -11.200 16.368  79.758  1.00 38.98  ? 305 THR A CG2 1 
ATOM   2140  N N   . GLN A 1 287 ? -7.360  16.957  77.327  1.00 34.29  ? 306 GLN A N   1 
ATOM   2141  C CA  . GLN A 1 287 ? -6.418  17.331  76.274  1.00 33.55  ? 306 GLN A CA  1 
ATOM   2142  C C   . GLN A 1 287 ? -5.684  16.099  75.747  1.00 31.67  ? 306 GLN A C   1 
ATOM   2143  O O   . GLN A 1 287 ? -5.512  15.932  74.532  1.00 31.29  ? 306 GLN A O   1 
ATOM   2144  C CB  . GLN A 1 287 ? -5.462  18.421  76.815  1.00 34.73  ? 306 GLN A CB  1 
ATOM   2145  C CG  . GLN A 1 287 ? -4.315  18.753  75.917  1.00 34.57  ? 306 GLN A CG  1 
ATOM   2146  C CD  . GLN A 1 287 ? -3.857  20.170  76.030  1.00 36.55  ? 306 GLN A CD  1 
ATOM   2147  O OE1 . GLN A 1 287 ? -4.373  20.966  76.818  1.00 37.52  ? 306 GLN A OE1 1 
ATOM   2148  N NE2 . GLN A 1 287 ? -2.868  20.504  75.253  1.00 36.97  ? 306 GLN A NE2 1 
ATOM   2149  N N   . LYS A 1 288 ? -5.267  15.204  76.627  1.00 34.60  ? 307 LYS A N   1 
ATOM   2150  C CA  . LYS A 1 288 ? -4.573  14.011  76.143  1.00 33.40  ? 307 LYS A CA  1 
ATOM   2151  C C   . LYS A 1 288 ? -5.460  13.210  75.201  1.00 33.24  ? 307 LYS A C   1 
ATOM   2152  O O   . LYS A 1 288 ? -5.019  12.737  74.147  1.00 32.96  ? 307 LYS A O   1 
ATOM   2153  C CB  . LYS A 1 288 ? -4.154  13.148  77.315  1.00 32.65  ? 307 LYS A CB  1 
ATOM   2154  C CG  . LYS A 1 288 ? -2.885  13.579  78.008  1.00 33.07  ? 307 LYS A CG  1 
ATOM   2155  C CD  . LYS A 1 288 ? -2.686  12.738  79.253  1.00 33.33  ? 307 LYS A CD  1 
ATOM   2156  C CE  . LYS A 1 288 ? -1.603  13.331  80.104  1.00 33.98  ? 307 LYS A CE  1 
ATOM   2157  N NZ  . LYS A 1 288 ? -1.700  12.969  81.574  1.00 34.78  ? 307 LYS A NZ  1 
ATOM   2158  N N   . ARG A 1 289 ? -6.720  13.056  75.582  1.00 34.43  ? 308 ARG A N   1 
ATOM   2159  C CA  . ARG A 1 289 ? -7.687  12.351  74.764  1.00 34.15  ? 308 ARG A CA  1 
ATOM   2160  C C   . ARG A 1 289 ? -7.978  13.075  73.463  1.00 35.23  ? 308 ARG A C   1 
ATOM   2161  O O   . ARG A 1 289 ? -8.031  12.447  72.407  1.00 35.11  ? 308 ARG A O   1 
ATOM   2162  C CB  . ARG A 1 289 ? -8.963  12.176  75.567  1.00 34.40  ? 308 ARG A CB  1 
ATOM   2163  C CG  . ARG A 1 289 ? -8.795  11.163  76.659  1.00 34.14  ? 308 ARG A CG  1 
ATOM   2164  C CD  . ARG A 1 289 ? -10.003 11.145  77.537  1.00 34.69  ? 308 ARG A CD  1 
ATOM   2165  N NE  . ARG A 1 289 ? -9.942  9.975   78.395  1.00 34.09  ? 308 ARG A NE  1 
ATOM   2166  C CZ  . ARG A 1 289 ? -10.538 9.907   79.574  1.00 34.67  ? 308 ARG A CZ  1 
ATOM   2167  N NH1 . ARG A 1 289 ? -11.241 10.938  80.051  1.00 35.83  ? 308 ARG A NH1 1 
ATOM   2168  N NH2 . ARG A 1 289 ? -10.445 8.779   80.276  1.00 34.34  ? 308 ARG A NH2 1 
ATOM   2169  N N   . ARG A 1 290 ? -8.217  14.394  73.519  1.00 32.11  ? 309 ARG A N   1 
ATOM   2170  C CA  . ARG A 1 290 ? -8.404  15.152  72.291  1.00 33.02  ? 309 ARG A CA  1 
ATOM   2171  C C   . ARG A 1 290 ? -7.219  14.934  71.368  1.00 32.61  ? 309 ARG A C   1 
ATOM   2172  O O   . ARG A 1 290 ? -7.391  14.746  70.165  1.00 33.11  ? 309 ARG A O   1 
ATOM   2173  C CB  . ARG A 1 290 ? -8.596  16.659  72.585  1.00 35.00  ? 309 ARG A CB  1 
ATOM   2174  C CG  . ARG A 1 290 ? -8.676  17.524  71.316  1.00 37.44  ? 309 ARG A CG  1 
ATOM   2175  C CD  . ARG A 1 290 ? -8.174  18.924  71.572  1.00 39.53  ? 309 ARG A CD  1 
ATOM   2176  N NE  . ARG A 1 290 ? -8.471  19.373  72.937  1.00 41.12  ? 309 ARG A NE  1 
ATOM   2177  C CZ  . ARG A 1 290 ? -7.640  20.087  73.681  1.00 42.35  ? 309 ARG A CZ  1 
ATOM   2178  N NH1 . ARG A 1 290 ? -6.490  20.545  73.183  1.00 42.92  ? 309 ARG A NH1 1 
ATOM   2179  N NH2 . ARG A 1 290 ? -7.963  20.340  74.951  1.00 42.56  ? 309 ARG A NH2 1 
ATOM   2180  N N   . VAL A 1 291 ? -5.998  14.972  71.904  1.00 32.42  ? 310 VAL A N   1 
ATOM   2181  C CA  . VAL A 1 291 ? -4.844  14.758  71.030  1.00 32.23  ? 310 VAL A CA  1 
ATOM   2182  C C   . VAL A 1 291 ? -4.897  13.349  70.473  1.00 31.23  ? 310 VAL A C   1 
ATOM   2183  O O   . VAL A 1 291 ? -4.573  13.107  69.307  1.00 31.43  ? 310 VAL A O   1 
ATOM   2184  C CB  . VAL A 1 291 ? -3.514  15.000  71.780  1.00 31.85  ? 310 VAL A CB  1 
ATOM   2185  C CG1 . VAL A 1 291 ? -2.297  14.658  70.901  1.00 31.67  ? 310 VAL A CG1 1 
ATOM   2186  C CG2 . VAL A 1 291 ? -3.433  16.393  72.228  1.00 33.05  ? 310 VAL A CG2 1 
ATOM   2187  N N   . ALA A 1 292 ? -5.272  12.396  71.315  1.00 32.02  ? 311 ALA A N   1 
ATOM   2188  C CA  . ALA A 1 292 ? -5.282  11.007  70.882  1.00 31.01  ? 311 ALA A CA  1 
ATOM   2189  C C   . ALA A 1 292 ? -6.306  10.788  69.772  1.00 31.83  ? 311 ALA A C   1 
ATOM   2190  O O   . ALA A 1 292 ? -5.983  10.191  68.750  1.00 31.76  ? 311 ALA A O   1 
ATOM   2191  C CB  . ALA A 1 292 ? -5.529  10.089  72.085  1.00 29.92  ? 311 ALA A CB  1 
ATOM   2192  N N   . LYS A 1 293 ? -7.514  11.332  69.916  1.00 33.03  ? 312 LYS A N   1 
ATOM   2193  C CA  . LYS A 1 293 ? -8.494  11.258  68.831  1.00 33.64  ? 312 LYS A CA  1 
ATOM   2194  C C   . LYS A 1 293 ? -7.959  11.876  67.548  1.00 34.69  ? 312 LYS A C   1 
ATOM   2195  O O   . LYS A 1 293 ? -8.145  11.327  66.457  1.00 34.95  ? 312 LYS A O   1 
ATOM   2196  C CB  . LYS A 1 293 ? -9.802  11.965  69.218  1.00 34.38  ? 312 LYS A CB  1 
ATOM   2197  C CG  . LYS A 1 293 ? -10.596 11.207  70.258  1.00 33.83  ? 312 LYS A CG  1 
ATOM   2198  C CD  . LYS A 1 293 ? -11.749 11.996  70.800  1.00 35.07  ? 312 LYS A CD  1 
ATOM   2199  C CE  . LYS A 1 293 ? -12.153 11.438  72.158  1.00 34.91  ? 312 LYS A CE  1 
ATOM   2200  N NZ  . LYS A 1 293 ? -13.540 11.911  72.571  1.00 36.10  ? 312 LYS A NZ  1 
ATOM   2201  N N   . ASP A 1 294 ? -7.313  13.029  67.660  1.00 31.77  ? 313 ASP A N   1 
ATOM   2202  C CA  . ASP A 1 294 ? -6.829  13.759  66.498  1.00 33.46  ? 313 ASP A CA  1 
ATOM   2203  C C   . ASP A 1 294 ? -5.581  13.135  65.892  1.00 33.06  ? 313 ASP A C   1 
ATOM   2204  O O   . ASP A 1 294 ? -5.333  13.284  64.702  1.00 34.19  ? 313 ASP A O   1 
ATOM   2205  C CB  . ASP A 1 294 ? -6.561  15.239  66.884  1.00 35.14  ? 313 ASP A CB  1 
ATOM   2206  C CG  . ASP A 1 294 ? -7.847  16.015  67.238  1.00 37.06  ? 313 ASP A CG  1 
ATOM   2207  O OD1 . ASP A 1 294 ? -8.956  15.573  66.797  1.00 37.33  ? 313 ASP A OD1 1 
ATOM   2208  O OD2 . ASP A 1 294 ? -7.760  17.079  67.947  1.00 38.19  ? 313 ASP A OD2 1 
ATOM   2209  N N   . SER A 1 295 ? -4.809  12.421  66.675  1.00 34.03  ? 314 SER A N   1 
ATOM   2210  C CA  . SER A 1 295 ? -3.559  11.811  66.225  1.00 33.32  ? 314 SER A CA  1 
ATOM   2211  C C   . SER A 1 295 ? -3.729  10.400  65.668  1.00 32.25  ? 314 SER A C   1 
ATOM   2212  O O   . SER A 1 295 ? -2.762  9.827   65.175  1.00 31.72  ? 314 SER A O   1 
ATOM   2213  C CB  . SER A 1 295 ? -2.568  11.785  67.399  1.00 32.17  ? 314 SER A CB  1 
ATOM   2214  O OG  . SER A 1 295 ? -2.328  13.093  67.838  1.00 33.37  ? 314 SER A OG  1 
ATOM   2215  N N   . LEU A 1 296 ? -4.931  9.861   65.672  1.00 33.99  ? 315 LEU A N   1 
ATOM   2216  C CA  . LEU A 1 296 ? -5.130  8.464   65.310  1.00 32.74  ? 315 LEU A CA  1 
ATOM   2217  C C   . LEU A 1 296 ? -5.108  8.205   63.805  1.00 33.22  ? 315 LEU A C   1 
ATOM   2218  O O   . LEU A 1 296 ? -4.580  7.176   63.368  1.00 32.12  ? 315 LEU A O   1 
ATOM   2219  C CB  . LEU A 1 296 ? -6.457  7.986   65.906  1.00 32.31  ? 315 LEU A CB  1 
ATOM   2220  C CG  . LEU A 1 296 ? -6.911  6.582   65.530  1.00 31.11  ? 315 LEU A CG  1 
ATOM   2221  C CD1 . LEU A 1 296 ? -5.954  5.457   65.956  1.00 29.74  ? 315 LEU A CD1 1 
ATOM   2222  C CD2 . LEU A 1 296 ? -8.315  6.354   66.184  1.00 30.96  ? 315 LEU A CD2 1 
ATOM   2223  N N   . LYS A 1 297 ? -5.674  9.100   62.993  1.00 34.43  ? 316 LYS A N   1 
ATOM   2224  C CA  . LYS A 1 297 ? -5.875  8.764   61.592  1.00 34.52  ? 316 LYS A CA  1 
ATOM   2225  C C   . LYS A 1 297 ? -4.550  8.413   60.940  1.00 34.37  ? 316 LYS A C   1 
ATOM   2226  O O   . LYS A 1 297 ? -4.445  7.407   60.240  1.00 33.61  ? 316 LYS A O   1 
ATOM   2227  C CB  . LYS A 1 297 ? -6.571  9.899   60.830  1.00 36.43  ? 316 LYS A CB  1 
ATOM   2228  C CG  . LYS A 1 297 ? -6.835  9.557   59.334  1.00 37.33  ? 316 LYS A CG  1 
ATOM   2229  C CD  . LYS A 1 297 ? -8.191  10.009  58.703  1.00 39.25  ? 316 LYS A CD  1 
ATOM   2230  C CE  . LYS A 1 297 ? -8.493  11.460  58.898  1.00 41.61  ? 316 LYS A CE  1 
ATOM   2231  N NZ  . LYS A 1 297 ? -7.466  12.295  58.245  1.00 43.10  ? 316 LYS A NZ  1 
ATOM   2232  N N   . PHE A 1 298 ? -3.510  9.201   61.178  1.00 34.86  ? 317 PHE A N   1 
ATOM   2233  C CA  . PHE A 1 298 ? -2.279  8.963   60.425  1.00 34.28  ? 317 PHE A CA  1 
ATOM   2234  C C   . PHE A 1 298 ? -1.700  7.583   60.703  1.00 32.38  ? 317 PHE A C   1 
ATOM   2235  O O   . PHE A 1 298 ? -1.398  6.842   59.754  1.00 32.12  ? 317 PHE A O   1 
ATOM   2236  C CB  . PHE A 1 298 ? -1.232  10.029  60.731  1.00 34.87  ? 317 PHE A CB  1 
ATOM   2237  C CG  . PHE A 1 298 ? 0.043   9.824   59.985  1.00 34.64  ? 317 PHE A CG  1 
ATOM   2238  C CD1 . PHE A 1 298 ? 0.102   10.012  58.604  1.00 35.13  ? 317 PHE A CD1 1 
ATOM   2239  C CD2 . PHE A 1 298 ? 1.190   9.412   60.648  1.00 33.95  ? 317 PHE A CD2 1 
ATOM   2240  C CE1 . PHE A 1 298 ? 1.289   9.811   57.896  1.00 35.07  ? 317 PHE A CE1 1 
ATOM   2241  C CE2 . PHE A 1 298 ? 2.384   9.193   59.939  1.00 33.86  ? 317 PHE A CE2 1 
ATOM   2242  C CZ  . PHE A 1 298 ? 2.428   9.389   58.556  1.00 34.29  ? 317 PHE A CZ  1 
ATOM   2243  N N   . PRO A 1 299 ? -1.416  7.218   61.947  1.00 33.57  ? 318 PRO A N   1 
ATOM   2244  C CA  . PRO A 1 299 ? -0.747  5.946   62.158  1.00 32.20  ? 318 PRO A CA  1 
ATOM   2245  C C   . PRO A 1 299 ? -1.652  4.777   61.836  1.00 31.88  ? 318 PRO A C   1 
ATOM   2246  O O   . PRO A 1 299 ? -1.152  3.761   61.351  1.00 31.05  ? 318 PRO A O   1 
ATOM   2247  C CB  . PRO A 1 299 ? -0.332  6.010   63.637  1.00 31.54  ? 318 PRO A CB  1 
ATOM   2248  C CG  . PRO A 1 299 ? -1.195  6.978   64.244  1.00 32.58  ? 318 PRO A CG  1 
ATOM   2249  C CD  . PRO A 1 299 ? -1.437  8.008   63.186  1.00 33.92  ? 318 PRO A CD  1 
ATOM   2250  N N   . LEU A 1 300 ? -2.962  4.922   62.009  1.00 31.21  ? 319 LEU A N   1 
ATOM   2251  C CA  . LEU A 1 300 ? -3.868  3.856   61.610  1.00 31.19  ? 319 LEU A CA  1 
ATOM   2252  C C   . LEU A 1 300 ? -3.824  3.606   60.107  1.00 31.30  ? 319 LEU A C   1 
ATOM   2253  O O   . LEU A 1 300 ? -3.824  2.457   59.657  1.00 31.25  ? 319 LEU A O   1 
ATOM   2254  C CB  . LEU A 1 300 ? -5.283  4.194   62.040  1.00 31.60  ? 319 LEU A CB  1 
ATOM   2255  C CG  . LEU A 1 300 ? -6.270  3.105   61.664  1.00 31.08  ? 319 LEU A CG  1 
ATOM   2256  C CD1 . LEU A 1 300 ? -5.900  1.768   62.323  1.00 30.08  ? 319 LEU A CD1 1 
ATOM   2257  C CD2 . LEU A 1 300 ? -7.618  3.599   62.091  1.00 31.36  ? 319 LEU A CD2 1 
ATOM   2258  N N   . ALA A 1 301 ? -3.800  4.665   59.324  1.00 31.51  ? 320 ALA A N   1 
ATOM   2259  C CA  . ALA A 1 301 ? -3.742  4.535   57.876  1.00 32.02  ? 320 ALA A CA  1 
ATOM   2260  C C   . ALA A 1 301 ? -2.432  3.902   57.440  1.00 31.30  ? 320 ALA A C   1 
ATOM   2261  O O   . ALA A 1 301 ? -2.381  3.176   56.440  1.00 31.62  ? 320 ALA A O   1 
ATOM   2262  C CB  . ALA A 1 301 ? -3.896  5.918   57.219  1.00 33.48  ? 320 ALA A CB  1 
ATOM   2263  N N   . CYS A 1 302 ? -1.336  4.224   58.139  1.00 33.74  ? 321 CYS A N   1 
ATOM   2264  C CA  . CYS A 1 302 ? -0.064  3.543   57.873  1.00 33.21  ? 321 CYS A CA  1 
ATOM   2265  C C   . CYS A 1 302 ? -0.205  2.040   58.099  1.00 32.36  ? 321 CYS A C   1 
ATOM   2266  O O   . CYS A 1 302 ? 0.066   1.223   57.198  1.00 32.61  ? 321 CYS A O   1 
ATOM   2267  C CB  . CYS A 1 302 ? 1.032   4.117   58.765  1.00 33.13  ? 321 CYS A CB  1 
ATOM   2268  S SG  . CYS A 1 302 ? 1.442   5.770   58.269  1.00 34.39  ? 321 CYS A SG  1 
ATOM   2269  N N   . PHE A 1 303 ? -0.685  1.665   59.283  1.00 31.71  ? 322 PHE A N   1 
ATOM   2270  C CA  . PHE A 1 303 ? -0.939  0.265   59.574  1.00 31.15  ? 322 PHE A CA  1 
ATOM   2271  C C   . PHE A 1 303 ? -1.789  -0.391  58.483  1.00 31.91  ? 322 PHE A C   1 
ATOM   2272  O O   . PHE A 1 303 ? -1.379  -1.364  57.848  1.00 31.93  ? 322 PHE A O   1 
ATOM   2273  C CB  . PHE A 1 303 ? -1.633  0.160   60.912  1.00 30.71  ? 322 PHE A CB  1 
ATOM   2274  C CG  . PHE A 1 303 ? -2.014  -1.214  61.260  1.00 30.12  ? 322 PHE A CG  1 
ATOM   2275  C CD1 . PHE A 1 303 ? -1.045  -2.120  61.679  1.00 29.58  ? 322 PHE A CD1 1 
ATOM   2276  C CD2 . PHE A 1 303 ? -3.337  -1.623  61.185  1.00 31.05  ? 322 PHE A CD2 1 
ATOM   2277  C CE1 . PHE A 1 303 ? -1.391  -3.427  61.998  1.00 29.81  ? 322 PHE A CE1 1 
ATOM   2278  C CE2 . PHE A 1 303 ? -3.679  -2.921  61.536  1.00 30.79  ? 322 PHE A CE2 1 
ATOM   2279  C CZ  . PHE A 1 303 ? -2.709  -3.804  61.961  1.00 30.57  ? 322 PHE A CZ  1 
ATOM   2280  N N   . LEU A 1 304 ? -2.981  0.167   58.235  1.00 32.05  ? 323 LEU A N   1 
ATOM   2281  C CA  . LEU A 1 304 ? -3.870  -0.403  57.232  1.00 32.50  ? 323 LEU A CA  1 
ATOM   2282  C C   . LEU A 1 304 ? -3.264  -0.355  55.839  1.00 33.27  ? 323 LEU A C   1 
ATOM   2283  O O   . LEU A 1 304 ? -3.659  -1.122  54.980  1.00 33.82  ? 323 LEU A O   1 
ATOM   2284  C CB  . LEU A 1 304 ? -5.212  0.320   57.260  1.00 33.17  ? 323 LEU A CB  1 
ATOM   2285  C CG  . LEU A 1 304 ? -6.024  0.143   58.534  1.00 32.80  ? 323 LEU A CG  1 
ATOM   2286  C CD1 . LEU A 1 304 ? -7.306  0.918   58.484  1.00 33.44  ? 323 LEU A CD1 1 
ATOM   2287  C CD2 . LEU A 1 304 ? -6.334  -1.311  58.790  1.00 32.56  ? 323 LEU A CD2 1 
ATOM   2288  N N   . ALA A 1 305 ? -2.301  0.511   55.588  1.00 33.81  ? 324 ALA A N   1 
ATOM   2289  C CA  . ALA A 1 305 ? -1.667  0.511   54.275  1.00 34.49  ? 324 ALA A CA  1 
ATOM   2290  C C   . ALA A 1 305 ? -0.964  -0.808  54.019  1.00 34.03  ? 324 ALA A C   1 
ATOM   2291  O O   . ALA A 1 305 ? -1.043  -1.357  52.926  1.00 34.89  ? 324 ALA A O   1 
ATOM   2292  C CB  . ALA A 1 305 ? -0.653  1.661   54.172  1.00 34.94  ? 324 ALA A CB  1 
ATOM   2293  N N   . GLY A 1 306 ? -0.241  -1.313  55.013  1.00 33.82  ? 325 GLY A N   1 
ATOM   2294  C CA  . GLY A 1 306 ? 0.658   -2.437  54.803  1.00 33.71  ? 325 GLY A CA  1 
ATOM   2295  C C   . GLY A 1 306 ? 0.198   -3.704  55.489  1.00 33.67  ? 325 GLY A C   1 
ATOM   2296  O O   . GLY A 1 306 ? 0.802   -4.768  55.344  1.00 33.81  ? 325 GLY A O   1 
ATOM   2297  N N   . ALA A 1 307 ? -0.892  -3.571  56.223  1.00 33.60  ? 326 ALA A N   1 
ATOM   2298  C CA  . ALA A 1 307 ? -1.357  -4.634  57.079  1.00 33.63  ? 326 ALA A CA  1 
ATOM   2299  C C   . ALA A 1 307 ? -1.709  -5.867  56.256  1.00 34.54  ? 326 ALA A C   1 
ATOM   2300  O O   . ALA A 1 307 ? -2.345  -5.784  55.197  1.00 35.34  ? 326 ALA A O   1 
ATOM   2301  C CB  . ALA A 1 307 ? -2.561  -4.135  57.882  1.00 33.64  ? 326 ALA A CB  1 
ATOM   2302  N N   . GLN A 1 308 ? -1.260  -7.015  56.742  1.00 33.78  ? 327 GLN A N   1 
ATOM   2303  C CA  . GLN A 1 308 ? -1.648  -8.297  56.194  1.00 34.70  ? 327 GLN A CA  1 
ATOM   2304  C C   . GLN A 1 308 ? -2.286  -9.097  57.315  1.00 34.88  ? 327 GLN A C   1 
ATOM   2305  O O   . GLN A 1 308 ? -2.516  -8.614  58.411  1.00 34.22  ? 327 GLN A O   1 
ATOM   2306  C CB  . GLN A 1 308 ? -0.461  -9.054  55.603  1.00 35.36  ? 327 GLN A CB  1 
ATOM   2307  C CG  . GLN A 1 308 ? 0.430   -8.210  54.762  1.00 35.15  ? 327 GLN A CG  1 
ATOM   2308  C CD  . GLN A 1 308 ? -0.147  -7.875  53.375  1.00 35.75  ? 327 GLN A CD  1 
ATOM   2309  O OE1 . GLN A 1 308 ? -0.623  -8.748  52.622  1.00 37.32  ? 327 GLN A OE1 1 
ATOM   2310  N NE2 . GLN A 1 308 ? -0.072  -6.624  53.025  1.00 35.60  ? 327 GLN A NE2 1 
ATOM   2311  N N   . GLU A 1 309 ? -2.518  -10.355 57.054  1.00 33.39  ? 328 GLU A N   1 
ATOM   2312  C CA  . GLU A 1 309 ? -3.024  -11.216 58.105  1.00 34.02  ? 328 GLU A CA  1 
ATOM   2313  C C   . GLU A 1 309 ? -2.003  -11.349 59.242  1.00 33.10  ? 328 GLU A C   1 
ATOM   2314  O O   . GLU A 1 309 ? -0.790  -11.241 59.052  1.00 32.84  ? 328 GLU A O   1 
ATOM   2315  C CB  . GLU A 1 309 ? -3.387  -12.555 57.482  1.00 36.42  ? 328 GLU A CB  1 
ATOM   2316  C CG  . GLU A 1 309 ? -3.774  -13.605 58.461  1.00 39.06  ? 328 GLU A CG  1 
ATOM   2317  C CD  . GLU A 1 309 ? -4.839  -14.543 57.888  1.00 41.63  ? 328 GLU A CD  1 
ATOM   2318  O OE1 . GLU A 1 309 ? -5.473  -14.156 56.855  1.00 42.53  ? 328 GLU A OE1 1 
ATOM   2319  O OE2 . GLU A 1 309 ? -5.004  -15.666 58.485  1.00 42.71  ? 328 GLU A OE2 1 
ATOM   2320  N N   . ASN A 1 310 ? -2.524  -11.521 60.449  1.00 31.75  ? 329 ASN A N   1 
ATOM   2321  C CA  . ASN A 1 310 ? -1.749  -11.607 61.667  1.00 30.75  ? 329 ASN A CA  1 
ATOM   2322  C C   . ASN A 1 310 ? -1.029  -10.312 62.014  1.00 29.09  ? 329 ASN A C   1 
ATOM   2323  O O   . ASN A 1 310 ? -0.044  -10.328 62.777  1.00 27.36  ? 329 ASN A O   1 
ATOM   2324  C CB  . ASN A 1 310 ? -0.707  -12.718 61.604  1.00 30.97  ? 329 ASN A CB  1 
ATOM   2325  C CG  . ASN A 1 310 ? -1.268  -14.023 61.151  1.00 32.74  ? 329 ASN A CG  1 
ATOM   2326  O OD1 . ASN A 1 310 ? -2.251  -14.539 61.697  1.00 33.44  ? 329 ASN A OD1 1 
ATOM   2327  N ND2 . ASN A 1 310 ? -0.634  -14.572 60.133  1.00 33.73  ? 329 ASN A ND2 1 
ATOM   2328  N N   . CYS A 1 311 ? -1.446  -9.188  61.456  1.00 31.03  ? 330 CYS A N   1 
ATOM   2329  C CA  . CYS A 1 311 ? -0.868  -7.907  61.841  1.00 29.64  ? 330 CYS A CA  1 
ATOM   2330  C C   . CYS A 1 311 ? -1.775  -7.247  62.862  1.00 29.12  ? 330 CYS A C   1 
ATOM   2331  O O   . CYS A 1 311 ? -3.006  -7.332  62.767  1.00 29.71  ? 330 CYS A O   1 
ATOM   2332  C CB  . CYS A 1 311 ? -0.694  -7.003  60.639  1.00 30.08  ? 330 CYS A CB  1 
ATOM   2333  S SG  . CYS A 1 311 ? 0.636   -7.512  59.568  1.00 30.52  ? 330 CYS A SG  1 
ATOM   2334  N N   . TYR A 1 312 ? -1.165  -6.614  63.850  1.00 29.14  ? 331 TYR A N   1 
ATOM   2335  C CA  . TYR A 1 312 ? -1.897  -6.042  64.971  1.00 27.44  ? 331 TYR A CA  1 
ATOM   2336  C C   . TYR A 1 312 ? -1.470  -4.607  65.212  1.00 26.98  ? 331 TYR A C   1 
ATOM   2337  O O   . TYR A 1 312 ? -0.331  -4.230  64.933  1.00 27.14  ? 331 TYR A O   1 
ATOM   2338  C CB  . TYR A 1 312 ? -1.695  -6.899  66.208  1.00 25.71  ? 331 TYR A CB  1 
ATOM   2339  C CG  . TYR A 1 312 ? -2.295  -8.300  66.079  1.00 26.38  ? 331 TYR A CG  1 
ATOM   2340  C CD1 . TYR A 1 312 ? -1.624  -9.311  65.439  1.00 27.29  ? 331 TYR A CD1 1 
ATOM   2341  C CD2 . TYR A 1 312 ? -3.536  -8.566  66.602  1.00 26.46  ? 331 TYR A CD2 1 
ATOM   2342  C CE1 . TYR A 1 312 ? -2.223  -10.582 65.294  1.00 28.17  ? 331 TYR A CE1 1 
ATOM   2343  C CE2 . TYR A 1 312 ? -4.115  -9.770  66.506  1.00 27.27  ? 331 TYR A CE2 1 
ATOM   2344  C CZ  . TYR A 1 312 ? -3.485  -10.791 65.862  1.00 28.39  ? 331 TYR A CZ  1 
ATOM   2345  O OH  . TYR A 1 312 ? -4.142  -12.011 65.812  1.00 29.68  ? 331 TYR A OH  1 
ATOM   2346  N N   . PHE A 1 313 ? -2.425  -3.817  65.729  1.00 26.75  ? 332 PHE A N   1 
ATOM   2347  C CA  . PHE A 1 313 ? -2.265  -2.393  65.991  1.00 26.74  ? 332 PHE A CA  1 
ATOM   2348  C C   . PHE A 1 313 ? -2.418  -2.136  67.474  1.00 25.18  ? 332 PHE A C   1 
ATOM   2349  O O   . PHE A 1 313 ? -3.397  -2.587  68.085  1.00 24.64  ? 332 PHE A O   1 
ATOM   2350  C CB  . PHE A 1 313 ? -3.327  -1.561  65.261  1.00 28.31  ? 332 PHE A CB  1 
ATOM   2351  C CG  . PHE A 1 313 ? -3.094  -0.037  65.253  1.00 28.78  ? 332 PHE A CG  1 
ATOM   2352  C CD1 . PHE A 1 313 ? -1.906  0.506   64.793  1.00 29.33  ? 332 PHE A CD1 1 
ATOM   2353  C CD2 . PHE A 1 313 ? -4.112  0.824   65.612  1.00 29.13  ? 332 PHE A CD2 1 
ATOM   2354  C CE1 . PHE A 1 313 ? -1.721  1.818   64.704  1.00 30.21  ? 332 PHE A CE1 1 
ATOM   2355  C CE2 . PHE A 1 313 ? -3.938  2.207   65.522  1.00 30.30  ? 332 PHE A CE2 1 
ATOM   2356  C CZ  . PHE A 1 313 ? -2.738  2.701   65.081  1.00 30.94  ? 332 PHE A CZ  1 
ATOM   2357  N N   . ILE A 1 314 ? -1.484  -1.362  68.033  1.00 27.18  ? 333 ILE A N   1 
ATOM   2358  C CA  . ILE A 1 314 ? -1.598  -0.817  69.389  1.00 26.49  ? 333 ILE A CA  1 
ATOM   2359  C C   . ILE A 1 314 ? -1.549  0.698   69.295  1.00 27.59  ? 333 ILE A C   1 
ATOM   2360  O O   . ILE A 1 314 ? -0.696  1.249   68.591  1.00 28.84  ? 333 ILE A O   1 
ATOM   2361  C CB  . ILE A 1 314 ? -0.483  -1.359  70.301  1.00 25.35  ? 333 ILE A CB  1 
ATOM   2362  C CG1 . ILE A 1 314 ? -0.568  -2.893  70.301  1.00 25.16  ? 333 ILE A CG1 1 
ATOM   2363  C CG2 . ILE A 1 314 ? -0.531  -0.778  71.714  1.00 25.99  ? 333 ILE A CG2 1 
ATOM   2364  C CD1 . ILE A 1 314 ? 0.393   -3.541  71.234  1.00 25.05  ? 333 ILE A CD1 1 
ATOM   2365  N N   . TYR A 1 315 ? -2.450  1.368   70.016  1.00 23.95  ? 334 TYR A N   1 
ATOM   2366  C CA  . TYR A 1 315 ? -2.576  2.824   69.988  1.00 25.43  ? 334 TYR A CA  1 
ATOM   2367  C C   . TYR A 1 315 ? -2.827  3.390   71.376  1.00 25.51  ? 334 TYR A C   1 
ATOM   2368  O O   . TYR A 1 315 ? -3.879  3.163   71.969  1.00 25.91  ? 334 TYR A O   1 
ATOM   2369  C CB  . TYR A 1 315 ? -3.725  3.258   69.061  1.00 26.83  ? 334 TYR A CB  1 
ATOM   2370  C CG  . TYR A 1 315 ? -3.781  4.751   68.833  1.00 28.55  ? 334 TYR A CG  1 
ATOM   2371  C CD1 . TYR A 1 315 ? -2.880  5.361   68.009  1.00 29.39  ? 334 TYR A CD1 1 
ATOM   2372  C CD2 . TYR A 1 315 ? -4.737  5.551   69.435  1.00 29.41  ? 334 TYR A CD2 1 
ATOM   2373  C CE1 . TYR A 1 315 ? -2.895  6.706   67.781  1.00 31.02  ? 334 TYR A CE1 1 
ATOM   2374  C CE2 . TYR A 1 315 ? -4.772  6.931   69.199  1.00 31.14  ? 334 TYR A CE2 1 
ATOM   2375  C CZ  . TYR A 1 315 ? -3.824  7.487   68.367  1.00 32.03  ? 334 TYR A CZ  1 
ATOM   2376  O OH  . TYR A 1 315 ? -3.763  8.843   68.097  1.00 33.99  ? 334 TYR A OH  1 
ATOM   2377  N N   . ASN A 1 316 ? -1.894  4.206   71.860  1.00 28.33  ? 335 ASN A N   1 
ATOM   2378  C CA  . ASN A 1 316 ? -1.983  4.810   73.186  1.00 28.75  ? 335 ASN A CA  1 
ATOM   2379  C C   . ASN A 1 316 ? -0.770  5.726   73.364  1.00 29.81  ? 335 ASN A C   1 
ATOM   2380  O O   . ASN A 1 316 ? 0.013   5.872   72.414  1.00 29.85  ? 335 ASN A O   1 
ATOM   2381  C CB  . ASN A 1 316 ? -2.018  3.697   74.260  1.00 27.82  ? 335 ASN A CB  1 
ATOM   2382  C CG  . ASN A 1 316 ? -0.796  2.836   74.228  1.00 26.90  ? 335 ASN A CG  1 
ATOM   2383  O OD1 . ASN A 1 316 ? 0.321   3.313   74.171  1.00 27.49  ? 335 ASN A OD1 1 
ATOM   2384  N ND2 . ASN A 1 316 ? -1.001  1.555   74.267  1.00 25.74  ? 335 ASN A ND2 1 
ATOM   2385  N N   . TRP A 1 317 ? -0.530  6.285   74.550  1.00 25.57  ? 336 TRP A N   1 
ATOM   2386  C CA  . TRP A 1 317 ? 0.696   7.039   74.781  1.00 26.43  ? 336 TRP A CA  1 
ATOM   2387  C C   . TRP A 1 317 ? 1.623   6.409   75.824  1.00 27.72  ? 336 TRP A C   1 
ATOM   2388  O O   . TRP A 1 317 ? 2.465   7.095   76.396  1.00 29.04  ? 336 TRP A O   1 
ATOM   2389  C CB  . TRP A 1 317 ? 0.350   8.485   75.189  1.00 27.28  ? 336 TRP A CB  1 
ATOM   2390  C CG  . TRP A 1 317 ? -0.577  8.652   76.400  1.00 28.24  ? 336 TRP A CG  1 
ATOM   2391  C CD1 . TRP A 1 317 ? -0.197  8.760   77.693  1.00 29.71  ? 336 TRP A CD1 1 
ATOM   2392  C CD2 . TRP A 1 317 ? -2.005  8.774   76.401  1.00 28.28  ? 336 TRP A CD2 1 
ATOM   2393  N NE1 . TRP A 1 317 ? -1.290  8.955   78.504  1.00 30.43  ? 336 TRP A NE1 1 
ATOM   2394  C CE2 . TRP A 1 317 ? -2.414  8.935   77.738  1.00 29.58  ? 336 TRP A CE2 1 
ATOM   2395  C CE3 . TRP A 1 317 ? -2.966  8.756   75.416  1.00 27.67  ? 336 TRP A CE3 1 
ATOM   2396  C CZ2 . TRP A 1 317 ? -3.733  9.069   78.110  1.00 30.60  ? 336 TRP A CZ2 1 
ATOM   2397  C CZ3 . TRP A 1 317 ? -4.288  8.912   75.789  1.00 28.55  ? 336 TRP A CZ3 1 
ATOM   2398  C CH2 . TRP A 1 317 ? -4.659  9.079   77.125  1.00 30.07  ? 336 TRP A CH2 1 
ATOM   2399  N N   . GLY A 1 318 ? 1.532   5.125   76.079  1.00 30.05  ? 337 GLY A N   1 
ATOM   2400  C CA  . GLY A 1 318 ? 2.378   4.538   77.102  1.00 30.81  ? 337 GLY A CA  1 
ATOM   2401  C C   . GLY A 1 318 ? 2.033   3.086   77.369  1.00 30.06  ? 337 GLY A C   1 
ATOM   2402  O O   . GLY A 1 318 ? 1.135   2.495   76.752  1.00 29.00  ? 337 GLY A O   1 
ATOM   2403  N N   . TYR A 1 319 ? 2.767   2.530   78.326  1.00 30.51  ? 338 TYR A N   1 
ATOM   2404  C CA  . TYR A 1 319 ? 2.671   1.124   78.690  1.00 29.37  ? 338 TYR A CA  1 
ATOM   2405  C C   . TYR A 1 319 ? 2.051   0.912   80.043  1.00 29.98  ? 338 TYR A C   1 
ATOM   2406  O O   . TYR A 1 319 ? 1.861   -0.240  80.439  1.00 29.35  ? 338 TYR A O   1 
ATOM   2407  C CB  . TYR A 1 319 ? 4.043   0.456   78.682  1.00 29.05  ? 338 TYR A CB  1 
ATOM   2408  C CG  . TYR A 1 319 ? 4.651   0.489   77.337  1.00 28.79  ? 338 TYR A CG  1 
ATOM   2409  C CD1 . TYR A 1 319 ? 4.060   -0.179  76.270  1.00 27.85  ? 338 TYR A CD1 1 
ATOM   2410  C CD2 . TYR A 1 319 ? 5.811   1.197   77.105  1.00 30.12  ? 338 TYR A CD2 1 
ATOM   2411  C CE1 . TYR A 1 319 ? 4.634   -0.156  75.013  1.00 27.59  ? 338 TYR A CE1 1 
ATOM   2412  C CE2 . TYR A 1 319 ? 6.374   1.238   75.859  1.00 29.87  ? 338 TYR A CE2 1 
ATOM   2413  C CZ  . TYR A 1 319 ? 5.790   0.546   74.829  1.00 28.56  ? 338 TYR A CZ  1 
ATOM   2414  O OH  . TYR A 1 319 ? 6.390   0.563   73.605  1.00 28.66  ? 338 TYR A OH  1 
ATOM   2415  N N   . ARG A 1 320 ? 1.775   1.971   80.771  1.00 29.96  ? 339 ARG A N   1 
ATOM   2416  C CA  . ARG A 1 320 ? 0.915   1.841   81.920  1.00 30.71  ? 339 ARG A CA  1 
ATOM   2417  C C   . ARG A 1 320 ? -0.521  1.887   81.457  1.00 30.58  ? 339 ARG A C   1 
ATOM   2418  O O   . ARG A 1 320 ? -0.851  2.486   80.418  1.00 30.78  ? 339 ARG A O   1 
ATOM   2419  C CB  . ARG A 1 320 ? 1.200   2.935   82.921  1.00 32.74  ? 339 ARG A CB  1 
ATOM   2420  C CG  . ARG A 1 320 ? 2.542   2.765   83.465  1.00 33.71  ? 339 ARG A CG  1 
ATOM   2421  C CD  . ARG A 1 320 ? 2.771   3.728   84.555  1.00 36.85  ? 339 ARG A CD  1 
ATOM   2422  N NE  . ARG A 1 320 ? 4.169   4.148   84.544  1.00 39.61  ? 339 ARG A NE  1 
ATOM   2423  C CZ  . ARG A 1 320 ? 5.120   3.725   85.372  1.00 41.63  ? 339 ARG A CZ  1 
ATOM   2424  N NH1 . ARG A 1 320 ? 4.869   2.825   86.326  1.00 41.91  ? 339 ARG A NH1 1 
ATOM   2425  N NH2 . ARG A 1 320 ? 6.351   4.235   85.252  1.00 43.05  ? 339 ARG A NH2 1 
ATOM   2426  N N   . MET A 1 321 ? -1.384  1.217   82.214  1.00 31.24  ? 340 MET A N   1 
ATOM   2427  C CA  . MET A 1 321 ? -2.797  1.236   81.857  1.00 31.75  ? 340 MET A CA  1 
ATOM   2428  C C   . MET A 1 321 ? -3.278  2.653   81.637  1.00 32.63  ? 340 MET A C   1 
ATOM   2429  O O   . MET A 1 321 ? -3.899  2.955   80.619  1.00 32.51  ? 340 MET A O   1 
ATOM   2430  C CB  . MET A 1 321 ? -3.643  0.584   82.941  1.00 32.46  ? 340 MET A CB  1 
ATOM   2431  C CG  . MET A 1 321 ? -4.922  0.028   82.409  1.00 32.87  ? 340 MET A CG  1 
ATOM   2432  S SD  . MET A 1 321 ? -5.974  -0.503  83.773  1.00 34.17  ? 340 MET A SD  1 
ATOM   2433  C CE  . MET A 1 321 ? -5.766  0.811   85.007  1.00 35.82  ? 340 MET A CE  1 
ATOM   2434  N N   . GLU A 1 322 ? -3.011  3.524   82.616  1.00 29.01  ? 341 GLU A N   1 
ATOM   2435  C CA  . GLU A 1 322 ? -3.479  4.918   82.600  1.00 30.22  ? 341 GLU A CA  1 
ATOM   2436  C C   . GLU A 1 322 ? -3.135  5.621   81.301  1.00 29.72  ? 341 GLU A C   1 
ATOM   2437  O O   . GLU A 1 322 ? -3.839  6.526   80.897  1.00 30.20  ? 341 GLU A O   1 
ATOM   2438  C CB  . GLU A 1 322 ? -2.883  5.709   83.782  1.00 32.05  ? 341 GLU A CB  1 
ATOM   2439  N N   . ASN A 1 323 ? -2.068  5.218   80.632  1.00 29.01  ? 342 ASN A N   1 
ATOM   2440  C CA  . ASN A 1 323 ? -1.582  5.924   79.449  1.00 28.66  ? 342 ASN A CA  1 
ATOM   2441  C C   . ASN A 1 323 ? -2.423  5.665   78.196  1.00 27.67  ? 342 ASN A C   1 
ATOM   2442  O O   . ASN A 1 323 ? -1.884  5.473   77.095  1.00 26.34  ? 342 ASN A O   1 
ATOM   2443  C CB  . ASN A 1 323 ? -0.117  5.557   79.206  1.00 28.61  ? 342 ASN A CB  1 
ATOM   2444  C CG  . ASN A 1 323 ? 0.777   5.765   80.451  1.00 28.90  ? 342 ASN A CG  1 
ATOM   2445  O OD1 . ASN A 1 323 ? 1.811   5.093   80.578  1.00 29.14  ? 342 ASN A OD1 1 
ATOM   2446  N ND2 . ASN A 1 323 ? 0.423   6.754   81.338  1.00 30.05  ? 342 ASN A ND2 1 
ATOM   2447  N N   . GLY A 1 324 ? -3.745  5.705   78.312  1.00 31.04  ? 343 GLY A N   1 
ATOM   2448  C CA  . GLY A 1 324 ? -4.555  5.610   77.113  1.00 30.11  ? 343 GLY A CA  1 
ATOM   2449  C C   . GLY A 1 324 ? -4.762  4.207   76.576  1.00 29.26  ? 343 GLY A C   1 
ATOM   2450  O O   . GLY A 1 324 ? -5.184  4.044   75.441  1.00 28.27  ? 343 GLY A O   1 
ATOM   2451  N N   . CYS A 1 325 ? -4.497  3.187   77.366  1.00 31.29  ? 344 CYS A N   1 
ATOM   2452  C CA  . CYS A 1 325 ? -4.465  1.829   76.842  1.00 29.65  ? 344 CYS A CA  1 
ATOM   2453  C C   . CYS A 1 325 ? -5.847  1.233   76.730  1.00 29.78  ? 344 CYS A C   1 
ATOM   2454  O O   . CYS A 1 325 ? -6.051  0.348   75.887  1.00 28.89  ? 344 CYS A O   1 
ATOM   2455  C CB  . CYS A 1 325 ? -3.616  0.940   77.744  1.00 29.83  ? 344 CYS A CB  1 
ATOM   2456  S SG  . CYS A 1 325 ? -1.871  1.352   77.605  1.00 30.13  ? 344 CYS A SG  1 
ATOM   2457  N N   . LEU A 1 326 ? -6.791  1.739   77.528  1.00 31.09  ? 345 LEU A N   1 
ATOM   2458  C CA  . LEU A 1 326 ? -8.188  1.353   77.518  1.00 31.77  ? 345 LEU A CA  1 
ATOM   2459  C C   . LEU A 1 326 ? -9.088  2.427   76.949  1.00 33.00  ? 345 LEU A C   1 
ATOM   2460  O O   . LEU A 1 326 ? -10.287 2.470   77.265  1.00 34.69  ? 345 LEU A O   1 
ATOM   2461  C CB  . LEU A 1 326 ? -8.636  1.044   78.933  1.00 33.48  ? 345 LEU A CB  1 
ATOM   2462  C CG  . LEU A 1 326 ? -7.747  0.057   79.669  1.00 33.04  ? 345 LEU A CG  1 
ATOM   2463  C CD1 . LEU A 1 326 ? -8.418  -0.288  80.956  1.00 34.71  ? 345 LEU A CD1 1 
ATOM   2464  C CD2 . LEU A 1 326 ? -7.540  -1.130  78.755  1.00 31.19  ? 345 LEU A CD2 1 
ATOM   2465  N N   . GLU A 1 327 ? -8.521  3.355   76.199  1.00 34.14  ? 346 GLU A N   1 
ATOM   2466  C CA  . GLU A 1 327 ? -9.347  4.261   75.419  1.00 34.41  ? 346 GLU A CA  1 
ATOM   2467  C C   . GLU A 1 327 ? -9.790  3.504   74.168  1.00 33.63  ? 346 GLU A C   1 
ATOM   2468  O O   . GLU A 1 327 ? -9.065  2.684   73.603  1.00 33.15  ? 346 GLU A O   1 
ATOM   2469  C CB  . GLU A 1 327 ? -8.592  5.546   75.034  1.00 33.93  ? 346 GLU A CB  1 
ATOM   2470  C CG  . GLU A 1 327 ? -8.133  6.440   76.209  1.00 35.33  ? 346 GLU A CG  1 
ATOM   2471  C CD  . GLU A 1 327 ? -9.257  7.123   76.940  1.00 37.74  ? 346 GLU A CD  1 
ATOM   2472  O OE1 . GLU A 1 327 ? -10.263 7.524   76.312  1.00 38.57  ? 346 GLU A OE1 1 
ATOM   2473  O OE2 . GLU A 1 327 ? -9.134  7.279   78.176  1.00 39.19  ? 346 GLU A OE2 1 
ATOM   2474  N N   . TRP A 1 328 ? -10.975 3.785   73.719  1.00 35.32  ? 347 TRP A N   1 
ATOM   2475  C CA  . TRP A 1 328 ? -11.448 3.188   72.485  1.00 34.64  ? 347 TRP A CA  1 
ATOM   2476  C C   . TRP A 1 328 ? -11.913 4.295   71.553  1.00 35.26  ? 347 TRP A C   1 
ATOM   2477  O O   . TRP A 1 328 ? -12.181 5.420   71.976  1.00 36.43  ? 347 TRP A O   1 
ATOM   2478  C CB  . TRP A 1 328 ? -12.543 2.217   72.783  1.00 35.88  ? 347 TRP A CB  1 
ATOM   2479  C CG  . TRP A 1 328 ? -12.724 1.128   71.783  1.00 35.09  ? 347 TRP A CG  1 
ATOM   2480  C CD1 . TRP A 1 328 ? -13.855 0.887   71.054  1.00 36.20  ? 347 TRP A CD1 1 
ATOM   2481  C CD2 . TRP A 1 328 ? -11.788 0.080   71.447  1.00 33.34  ? 347 TRP A CD2 1 
ATOM   2482  N NE1 . TRP A 1 328 ? -13.673 -0.213  70.270  1.00 35.86  ? 347 TRP A NE1 1 
ATOM   2483  C CE2 . TRP A 1 328 ? -12.421 -0.736  70.494  1.00 33.90  ? 347 TRP A CE2 1 
ATOM   2484  C CE3 . TRP A 1 328 ? -10.483 -0.230  71.857  1.00 31.94  ? 347 TRP A CE3 1 
ATOM   2485  C CZ2 . TRP A 1 328 ? -11.803 -1.866  69.942  1.00 33.00  ? 347 TRP A CZ2 1 
ATOM   2486  C CZ3 . TRP A 1 328 ? -9.857  -1.340  71.323  1.00 30.92  ? 347 TRP A CZ3 1 
ATOM   2487  C CH2 . TRP A 1 328 ? -10.530 -2.165  70.361  1.00 31.58  ? 347 TRP A CH2 1 
ATOM   2488  N N   . TYR A 1 329 ? -12.000 3.948   70.270  1.00 33.98  ? 348 TYR A N   1 
ATOM   2489  C CA  . TYR A 1 329 ? -12.236 4.866   69.199  1.00 34.41  ? 348 TYR A CA  1 
ATOM   2490  C C   . TYR A 1 329 ? -13.207 4.261   68.196  1.00 35.26  ? 348 TYR A C   1 
ATOM   2491  O O   . TYR A 1 329 ? -13.154 3.059   67.930  1.00 35.05  ? 348 TYR A O   1 
ATOM   2492  C CB  . TYR A 1 329 ? -10.912 5.207   68.505  1.00 33.09  ? 348 TYR A CB  1 
ATOM   2493  C CG  . TYR A 1 329 ? -9.858  5.712   69.448  1.00 32.36  ? 348 TYR A CG  1 
ATOM   2494  C CD1 . TYR A 1 329 ? -9.062  4.830   70.147  1.00 31.40  ? 348 TYR A CD1 1 
ATOM   2495  C CD2 . TYR A 1 329 ? -9.656  7.105   69.658  1.00 32.85  ? 348 TYR A CD2 1 
ATOM   2496  C CE1 . TYR A 1 329 ? -8.076  5.289   71.020  1.00 31.18  ? 348 TYR A CE1 1 
ATOM   2497  C CE2 . TYR A 1 329 ? -8.681  7.558   70.538  1.00 32.38  ? 348 TYR A CE2 1 
ATOM   2498  C CZ  . TYR A 1 329 ? -7.890  6.649   71.214  1.00 31.65  ? 348 TYR A CZ  1 
ATOM   2499  O OH  . TYR A 1 329 ? -6.924  7.072   72.102  1.00 31.87  ? 348 TYR A OH  1 
ATOM   2500  N N   . PRO A 1 330 ? -14.081 5.072   67.600  1.00 34.17  ? 349 PRO A N   1 
ATOM   2501  C CA  . PRO A 1 330 ? -15.056 4.494   66.647  1.00 34.72  ? 349 PRO A CA  1 
ATOM   2502  C C   . PRO A 1 330 ? -14.396 3.804   65.465  1.00 33.91  ? 349 PRO A C   1 
ATOM   2503  O O   . PRO A 1 330 ? -14.949 2.839   64.915  1.00 34.33  ? 349 PRO A O   1 
ATOM   2504  C CB  . PRO A 1 330 ? -15.884 5.717   66.223  1.00 36.79  ? 349 PRO A CB  1 
ATOM   2505  C CG  . PRO A 1 330 ? -14.958 6.951   66.620  1.00 37.37  ? 349 PRO A CG  1 
ATOM   2506  C CD  . PRO A 1 330 ? -14.202 6.547   67.765  1.00 35.80  ? 349 PRO A CD  1 
ATOM   2507  N N   . GLU A 1 331 ? -13.220 4.265   65.058  1.00 34.79  ? 350 GLU A N   1 
ATOM   2508  C CA  . GLU A 1 331 ? -12.506 3.633   63.960  1.00 34.38  ? 350 GLU A CA  1 
ATOM   2509  C C   . GLU A 1 331 ? -12.237 2.160   64.224  1.00 33.69  ? 350 GLU A C   1 
ATOM   2510  O O   . GLU A 1 331 ? -12.026 1.406   63.284  1.00 34.75  ? 350 GLU A O   1 
ATOM   2511  C CB  . GLU A 1 331 ? -11.178 4.360   63.730  1.00 34.64  ? 350 GLU A CB  1 
ATOM   2512  C CG  . GLU A 1 331 ? -11.261 5.673   62.952  1.00 36.11  ? 350 GLU A CG  1 
ATOM   2513  C CD  . GLU A 1 331 ? -11.557 6.929   63.808  1.00 37.23  ? 350 GLU A CD  1 
ATOM   2514  O OE1 . GLU A 1 331 ? -11.760 6.787   65.035  1.00 36.36  ? 350 GLU A OE1 1 
ATOM   2515  O OE2 . GLU A 1 331 ? -11.603 8.086   63.241  1.00 39.18  ? 350 GLU A OE2 1 
ATOM   2516  N N   . PHE A 1 332 ? -12.209 1.763   65.473  1.00 33.60  ? 351 PHE A N   1 
ATOM   2517  C CA  . PHE A 1 332 ? -11.927 0.407   65.890  1.00 32.97  ? 351 PHE A CA  1 
ATOM   2518  C C   . PHE A 1 332 ? -13.183 -0.452  65.900  1.00 33.42  ? 351 PHE A C   1 
ATOM   2519  O O   . PHE A 1 332 ? -13.079 -1.665  66.070  1.00 33.46  ? 351 PHE A O   1 
ATOM   2520  C CB  . PHE A 1 332 ? -11.263 0.421   67.282  1.00 31.97  ? 351 PHE A CB  1 
ATOM   2521  C CG  . PHE A 1 332 ? -9.856  1.012   67.293  1.00 31.36  ? 351 PHE A CG  1 
ATOM   2522  C CD1 . PHE A 1 332 ? -9.167  1.238   66.110  1.00 31.52  ? 351 PHE A CD1 1 
ATOM   2523  C CD2 . PHE A 1 332 ? -9.247  1.350   68.481  1.00 31.28  ? 351 PHE A CD2 1 
ATOM   2524  C CE1 . PHE A 1 332 ? -7.909  1.765   66.115  1.00 31.41  ? 351 PHE A CE1 1 
ATOM   2525  C CE2 . PHE A 1 332 ? -8.004  1.912   68.494  1.00 30.89  ? 351 PHE A CE2 1 
ATOM   2526  C CZ  . PHE A 1 332 ? -7.321  2.108   67.312  1.00 30.82  ? 351 PHE A CZ  1 
ATOM   2527  N N   . ASP A 1 333 ? -14.361 0.149   65.673  1.00 34.50  ? 352 ASP A N   1 
ATOM   2528  C CA  . ASP A 1 333 ? -15.606 -0.597  65.572  1.00 35.32  ? 352 ASP A CA  1 
ATOM   2529  C C   . ASP A 1 333 ? -16.188 -0.642  64.158  1.00 36.44  ? 352 ASP A C   1 
ATOM   2530  O O   . ASP A 1 333 ? -17.172 -1.370  63.920  1.00 37.65  ? 352 ASP A O   1 
ATOM   2531  C CB  . ASP A 1 333 ? -16.663 0.012   66.495  1.00 36.01  ? 352 ASP A CB  1 
ATOM   2532  C CG  . ASP A 1 333 ? -16.289 -0.052  67.937  1.00 36.02  ? 352 ASP A CG  1 
ATOM   2533  O OD1 . ASP A 1 333 ? -15.541 -0.957  68.342  1.00 35.30  ? 352 ASP A OD1 1 
ATOM   2534  O OD2 . ASP A 1 333 ? -16.768 0.813   68.685  1.00 37.06  ? 352 ASP A OD2 1 
ATOM   2535  N N   . LYS A 1 334 ? -15.639 0.117   63.255  1.00 36.29  ? 353 LYS A N   1 
ATOM   2536  C CA  . LYS A 1 334 ? -16.244 0.221   61.951  1.00 38.10  ? 353 LYS A CA  1 
ATOM   2537  C C   . LYS A 1 334 ? -15.935 -1.029  61.173  1.00 38.26  ? 353 LYS A C   1 
ATOM   2538  O O   . LYS A 1 334 ? -14.936 -1.702  61.452  1.00 37.68  ? 353 LYS A O   1 
ATOM   2539  C CB  . LYS A 1 334 ? -15.719 1.424   61.207  1.00 39.35  ? 353 LYS A CB  1 
ATOM   2540  C CG  . LYS A 1 334 ? -16.273 2.636   61.800  1.00 40.20  ? 353 LYS A CG  1 
ATOM   2541  C CD  . LYS A 1 334 ? -15.931 3.836   61.022  1.00 42.00  ? 353 LYS A CD  1 
ATOM   2542  C CE  . LYS A 1 334 ? -16.117 5.081   61.898  1.00 42.85  ? 353 LYS A CE  1 
ATOM   2543  N NZ  . LYS A 1 334 ? -16.620 6.185   61.061  1.00 45.09  ? 353 LYS A NZ  1 
ATOM   2544  N N   . PRO A 1 335 ? -16.827 -1.391  60.250  1.00 37.73  ? 354 PRO A N   1 
ATOM   2545  C CA  . PRO A 1 335 ? -16.525 -2.474  59.312  1.00 38.26  ? 354 PRO A CA  1 
ATOM   2546  C C   . PRO A 1 335 ? -15.253 -2.145  58.544  1.00 38.45  ? 354 PRO A C   1 
ATOM   2547  O O   . PRO A 1 335 ? -15.125 -1.094  57.939  1.00 39.31  ? 354 PRO A O   1 
ATOM   2548  C CB  . PRO A 1 335 ? -17.742 -2.471  58.401  1.00 40.15  ? 354 PRO A CB  1 
ATOM   2549  C CG  . PRO A 1 335 ? -18.803 -1.986  59.283  1.00 39.94  ? 354 PRO A CG  1 
ATOM   2550  C CD  . PRO A 1 335 ? -18.215 -0.932  60.127  1.00 38.62  ? 354 PRO A CD  1 
ATOM   2551  N N   . LEU A 1 336 ? -14.298 -3.063  58.607  1.00 37.85  ? 355 LEU A N   1 
ATOM   2552  C CA  . LEU A 1 336 ? -13.102 -2.958  57.779  1.00 38.13  ? 355 LEU A CA  1 
ATOM   2553  C C   . LEU A 1 336 ? -13.120 -4.006  56.679  1.00 39.34  ? 355 LEU A C   1 
ATOM   2554  O O   . LEU A 1 336 ? -13.203 -3.684  55.488  1.00 41.00  ? 355 LEU A O   1 
ATOM   2555  C CB  . LEU A 1 336 ? -11.839 -3.134  58.610  1.00 37.07  ? 355 LEU A CB  1 
ATOM   2556  C CG  . LEU A 1 336 ? -10.495 -3.178  57.880  1.00 37.22  ? 355 LEU A CG  1 
ATOM   2557  C CD1 . LEU A 1 336 ? -10.200 -1.893  57.136  1.00 37.59  ? 355 LEU A CD1 1 
ATOM   2558  C CD2 . LEU A 1 336 ? -9.393  -3.458  58.943  1.00 35.97  ? 355 LEU A CD2 1 
ATOM   2559  N N   . GLY A 1 337 ? -13.082 -5.268  57.064  1.00 39.27  ? 356 GLY A N   1 
ATOM   2560  C CA  . GLY A 1 337 ? -13.162 -6.346  56.115  1.00 40.59  ? 356 GLY A CA  1 
ATOM   2561  C C   . GLY A 1 337 ? -11.818 -6.666  55.482  1.00 40.91  ? 356 GLY A C   1 
ATOM   2562  O O   . GLY A 1 337 ? -10.851 -5.904  55.545  1.00 40.35  ? 356 GLY A O   1 
ATOM   2563  N N   . LYS A 1 338 ? -11.805 -7.851  54.876  1.00 39.62  ? 357 LYS A N   1 
ATOM   2564  C CA  . LYS A 1 338 ? -10.641 -8.361  54.181  1.00 40.80  ? 357 LYS A CA  1 
ATOM   2565  C C   . LYS A 1 338 ? -10.094 -7.325  53.204  1.00 41.34  ? 357 LYS A C   1 
ATOM   2566  O O   . LYS A 1 338 ? -10.880 -6.600  52.565  1.00 42.43  ? 357 LYS A O   1 
ATOM   2567  C CB  . LYS A 1 338 ? -11.078 -9.621  53.410  1.00 43.54  ? 357 LYS A CB  1 
ATOM   2568  C CG  . LYS A 1 338 ? -9.967  -10.458 52.853  1.00 45.60  ? 357 LYS A CG  1 
ATOM   2569  C CD  . LYS A 1 338 ? -10.434 -11.742 52.085  1.00 48.41  ? 357 LYS A CD  1 
ATOM   2570  C CE  . LYS A 1 338 ? -11.662 -11.523 51.235  1.00 50.81  ? 357 LYS A CE  1 
ATOM   2571  N NZ  . LYS A 1 338 ? -11.612 -12.302 49.934  1.00 53.84  ? 357 LYS A NZ  1 
ATOM   2572  N N   . PRO A 1 339 ? -8.773  -7.220  53.065  1.00 40.29  ? 358 PRO A N   1 
ATOM   2573  C CA  . PRO A 1 339 ? -8.231  -6.443  51.952  1.00 41.71  ? 358 PRO A CA  1 
ATOM   2574  C C   . PRO A 1 339 ? -8.793  -7.003  50.658  1.00 44.36  ? 358 PRO A C   1 
ATOM   2575  O O   . PRO A 1 339 ? -9.038  -8.208  50.534  1.00 45.28  ? 358 PRO A O   1 
ATOM   2576  C CB  . PRO A 1 339 ? -6.717  -6.646  52.056  1.00 41.39  ? 358 PRO A CB  1 
ATOM   2577  C CG  . PRO A 1 339 ? -6.477  -7.209  53.411  1.00 40.00  ? 358 PRO A CG  1 
ATOM   2578  C CD  . PRO A 1 339 ? -7.724  -7.925  53.828  1.00 39.46  ? 358 PRO A CD  1 
ATOM   2579  N N   . VAL A 1 340 ? -9.017  -6.112  49.696  1.00 42.07  ? 359 VAL A N   1 
ATOM   2580  C CA  . VAL A 1 340 ? -9.422  -6.534  48.361  1.00 45.50  ? 359 VAL A CA  1 
ATOM   2581  C C   . VAL A 1 340 ? -8.347  -6.212  47.325  1.00 47.44  ? 359 VAL A C   1 
ATOM   2582  O O   . VAL A 1 340 ? -8.563  -6.386  46.129  1.00 50.69  ? 359 VAL A O   1 
ATOM   2583  C CB  . VAL A 1 340 ? -10.773 -5.934  47.974  1.00 46.74  ? 359 VAL A CB  1 
ATOM   2584  C CG1 . VAL A 1 340 ? -11.809 -6.268  49.048  1.00 44.97  ? 359 VAL A CG1 1 
ATOM   2585  C CG2 . VAL A 1 340 ? -10.669 -4.429  47.816  1.00 46.31  ? 359 VAL A CG2 1 
ATOM   2586  N N   . GLY A 1 341 ? -7.182  -5.780  47.770  1.00 45.77  ? 360 GLY A N   1 
ATOM   2587  C CA  . GLY A 1 341 ? -6.051  -5.585  46.888  1.00 47.53  ? 360 GLY A CA  1 
ATOM   2588  C C   . GLY A 1 341 ? -4.822  -5.258  47.702  1.00 44.68  ? 360 GLY A C   1 
ATOM   2589  O O   . GLY A 1 341 ? -4.906  -4.898  48.884  1.00 41.10  ? 360 GLY A O   1 
ATOM   2590  N N   . GLU A 1 342 ? -3.672  -5.416  47.055  1.00 46.38  ? 361 GLU A N   1 
ATOM   2591  C CA  . GLU A 1 342 ? -2.396  -5.159  47.704  1.00 43.98  ? 361 GLU A CA  1 
ATOM   2592  C C   . GLU A 1 342 ? -2.133  -3.651  47.836  1.00 41.62  ? 361 GLU A C   1 
ATOM   2593  O O   . GLU A 1 342 ? -2.716  -2.815  47.143  1.00 42.76  ? 361 GLU A O   1 
ATOM   2594  C CB  . GLU A 1 342 ? -1.261  -5.808  46.911  1.00 47.30  ? 361 GLU A CB  1 
ATOM   2595  C CG  . GLU A 1 342 ? -1.401  -7.308  46.619  1.00 49.37  ? 361 GLU A CG  1 
ATOM   2596  C CD  . GLU A 1 342 ? -1.109  -8.247  47.819  1.00 47.52  ? 361 GLU A CD  1 
ATOM   2597  O OE1 . GLU A 1 342 ? -0.741  -7.782  48.924  1.00 44.96  ? 361 GLU A OE1 1 
ATOM   2598  O OE2 . GLU A 1 342 ? -1.256  -9.488  47.645  1.00 49.00  ? 361 GLU A OE2 1 
ATOM   2599  N N   . MET A 1 343 ? -1.242  -3.313  48.766  1.00 43.52  ? 362 MET A N   1 
ATOM   2600  C CA  . MET A 1 343 ? -0.809  -1.935  48.925  1.00 43.05  ? 362 MET A CA  1 
ATOM   2601  C C   . MET A 1 343 ? -0.243  -1.386  47.619  1.00 45.30  ? 362 MET A C   1 
ATOM   2602  O O   . MET A 1 343 ? 0.475   -2.079  46.896  1.00 46.90  ? 362 MET A O   1 
ATOM   2603  C CB  . MET A 1 343 ? 0.255   -1.851  50.020  1.00 41.45  ? 362 MET A CB  1 
ATOM   2604  C CG  . MET A 1 343 ? 1.216   -0.707  49.845  1.00 41.55  ? 362 MET A CG  1 
ATOM   2605  S SD  . MET A 1 343 ? 1.802   -0.157  51.435  1.00 39.58  ? 362 MET A SD  1 
ATOM   2606  C CE  . MET A 1 343 ? 3.067   -1.294  51.860  1.00 39.60  ? 362 MET A CE  1 
ATOM   2607  N N   . VAL A 1 344 ? -0.529  -0.111  47.345  1.00 43.05  ? 363 VAL A N   1 
ATOM   2608  C CA  . VAL A 1 344 ? 0.007   0.560   46.170  1.00 45.65  ? 363 VAL A CA  1 
ATOM   2609  C C   . VAL A 1 344 ? 0.913   1.704   46.607  1.00 44.51  ? 363 VAL A C   1 
ATOM   2610  O O   . VAL A 1 344 ? 0.544   2.501   47.476  1.00 42.82  ? 363 VAL A O   1 
ATOM   2611  C CB  . VAL A 1 344 ? -1.099  1.109   45.238  1.00 47.89  ? 363 VAL A CB  1 
ATOM   2612  C CG1 . VAL A 1 344 ? -0.465  1.646   43.959  1.00 50.83  ? 363 VAL A CG1 1 
ATOM   2613  C CG2 . VAL A 1 344 ? -2.140  0.048   44.938  1.00 48.95  ? 363 VAL A CG2 1 
ATOM   2614  N N   . ARG A 1 345 ? 2.076   1.807   45.974  1.00 47.95  ? 364 ARG A N   1 
ATOM   2615  C CA  . ARG A 1 345 ? 3.011   2.861   46.296  1.00 47.76  ? 364 ARG A CA  1 
ATOM   2616  C C   . ARG A 1 345 ? 3.293   3.753   45.090  1.00 50.05  ? 364 ARG A C   1 
ATOM   2617  O O   . ARG A 1 345 ? 3.758   3.275   44.055  1.00 52.35  ? 364 ARG A O   1 
ATOM   2618  C CB  . ARG A 1 345 ? 4.347   2.313   46.791  1.00 47.80  ? 364 ARG A CB  1 
ATOM   2619  C CG  . ARG A 1 345 ? 5.392   3.443   46.739  1.00 48.23  ? 364 ARG A CG  1 
ATOM   2620  C CD  . ARG A 1 345 ? 6.426   3.418   47.866  1.00 47.77  ? 364 ARG A CD  1 
ATOM   2621  N NE  . ARG A 1 345 ? 7.677   4.089   47.528  1.00 49.22  ? 364 ARG A NE  1 
ATOM   2622  C CZ  . ARG A 1 345 ? 8.854   3.481   47.452  1.00 50.36  ? 364 ARG A CZ  1 
ATOM   2623  N NH1 . ARG A 1 345 ? 8.958   2.170   47.550  1.00 50.14  ? 364 ARG A NH1 1 
ATOM   2624  N NH2 . ARG A 1 345 ? 9.956   4.211   47.288  1.00 51.24  ? 364 ARG A NH2 1 
ATOM   2625  N N   . ASP A 1 346 ? 3.102   5.059   45.274  1.00 49.30  ? 365 ASP A N   1 
ATOM   2626  C CA  . ASP A 1 346 ? 3.522   6.103   44.336  1.00 51.81  ? 365 ASP A CA  1 
ATOM   2627  C C   . ASP A 1 346 ? 4.365   7.116   45.129  1.00 50.54  ? 365 ASP A C   1 
ATOM   2628  O O   . ASP A 1 346 ? 3.838   8.068   45.715  1.00 49.75  ? 365 ASP A O   1 
ATOM   2629  C CB  . ASP A 1 346 ? 2.309   6.763   43.679  1.00 53.99  ? 365 ASP A CB  1 
ATOM   2630  C CG  . ASP A 1 346 ? 2.671   8.014   42.876  1.00 56.83  ? 365 ASP A CG  1 
ATOM   2631  O OD1 . ASP A 1 346 ? 3.869   8.224   42.573  1.00 57.60  ? 365 ASP A OD1 1 
ATOM   2632  O OD2 . ASP A 1 346 ? 1.745   8.790   42.523  1.00 58.53  ? 365 ASP A OD2 1 
ATOM   2633  N N   . GLY A 1 347 ? 5.677   6.910   45.123  1.00 50.66  ? 366 GLY A N   1 
ATOM   2634  C CA  . GLY A 1 347 ? 6.542   7.720   45.950  1.00 49.73  ? 366 GLY A CA  1 
ATOM   2635  C C   . GLY A 1 347 ? 6.241   7.430   47.403  1.00 47.35  ? 366 GLY A C   1 
ATOM   2636  O O   . GLY A 1 347 ? 6.115   6.265   47.797  1.00 46.85  ? 366 GLY A O   1 
ATOM   2637  N N   . TRP A 1 348 ? 6.106   8.502   48.207  1.00 47.93  ? 367 TRP A N   1 
ATOM   2638  C CA  . TRP A 1 348 ? 5.801   8.409   49.634  1.00 45.45  ? 367 TRP A CA  1 
ATOM   2639  C C   . TRP A 1 348 ? 4.311   8.243   49.901  1.00 44.57  ? 367 TRP A C   1 
ATOM   2640  O O   . TRP A 1 348 ? 3.906   8.154   51.075  1.00 42.63  ? 367 TRP A O   1 
ATOM   2641  C CB  . TRP A 1 348 ? 6.338   9.654   50.382  1.00 45.36  ? 367 TRP A CB  1 
ATOM   2642  C CG  . TRP A 1 348 ? 7.814   9.848   50.145  1.00 46.16  ? 367 TRP A CG  1 
ATOM   2643  C CD1 . TRP A 1 348 ? 8.415   10.817  49.392  1.00 48.00  ? 367 TRP A CD1 1 
ATOM   2644  C CD2 . TRP A 1 348 ? 8.861   9.011   50.635  1.00 45.62  ? 367 TRP A CD2 1 
ATOM   2645  N NE1 . TRP A 1 348 ? 9.774   10.627  49.386  1.00 48.55  ? 367 TRP A NE1 1 
ATOM   2646  C CE2 . TRP A 1 348 ? 10.072  9.526   50.144  1.00 47.00  ? 367 TRP A CE2 1 
ATOM   2647  C CE3 . TRP A 1 348 ? 8.890   7.886   51.455  1.00 44.19  ? 367 TRP A CE3 1 
ATOM   2648  C CZ2 . TRP A 1 348 ? 11.293  8.939   50.429  1.00 47.12  ? 367 TRP A CZ2 1 
ATOM   2649  C CZ3 . TRP A 1 348 ? 10.092  7.299   51.729  1.00 44.31  ? 367 TRP A CZ3 1 
ATOM   2650  C CH2 . TRP A 1 348 ? 11.282  7.819   51.216  1.00 45.71  ? 367 TRP A CH2 1 
ATOM   2651  N N   . LYS A 1 349 ? 3.495   8.194   48.839  1.00 46.24  ? 368 LYS A N   1 
ATOM   2652  C CA  . LYS A 1 349 ? 2.054   7.985   48.955  1.00 46.17  ? 368 LYS A CA  1 
ATOM   2653  C C   . LYS A 1 349 ? 1.769   6.493   48.884  1.00 45.22  ? 368 LYS A C   1 
ATOM   2654  O O   . LYS A 1 349 ? 2.344   5.787   48.065  1.00 46.65  ? 368 LYS A O   1 
ATOM   2655  C CB  . LYS A 1 349 ? 1.298   8.709   47.831  1.00 49.07  ? 368 LYS A CB  1 
ATOM   2656  C CG  . LYS A 1 349 ? 1.368   10.244  47.845  1.00 50.83  ? 368 LYS A CG  1 
ATOM   2657  C CD  . LYS A 1 349 ? 0.976   10.815  46.476  1.00 54.55  ? 368 LYS A CD  1 
ATOM   2658  C CE  . LYS A 1 349 ? 2.141   11.573  45.778  1.00 57.01  ? 368 LYS A CE  1 
ATOM   2659  N NZ  . LYS A 1 349 ? 3.110   10.779  44.888  1.00 58.37  ? 368 LYS A NZ  1 
ATOM   2660  N N   . LEU A 1 350 ? 0.883   6.021   49.752  1.00 43.28  ? 369 LEU A N   1 
ATOM   2661  C CA  . LEU A 1 350 ? 0.481   4.631   49.779  1.00 42.66  ? 369 LEU A CA  1 
ATOM   2662  C C   . LEU A 1 350 ? -1.034  4.537   49.788  1.00 43.09  ? 369 LEU A C   1 
ATOM   2663  O O   . LEU A 1 350 ? -1.721  5.401   50.356  1.00 42.71  ? 369 LEU A O   1 
ATOM   2664  C CB  . LEU A 1 350 ? 1.017   3.921   51.021  1.00 41.12  ? 369 LEU A CB  1 
ATOM   2665  C CG  . LEU A 1 350 ? 2.485   4.111   51.403  1.00 41.11  ? 369 LEU A CG  1 
ATOM   2666  C CD1 . LEU A 1 350 ? 2.784   3.452   52.759  1.00 39.51  ? 369 LEU A CD1 1 
ATOM   2667  C CD2 . LEU A 1 350 ? 3.331   3.532   50.299  1.00 42.89  ? 369 LEU A CD2 1 
ATOM   2668  N N   . SER A 1 351 ? -1.557  3.463   49.181  1.00 41.37  ? 370 SER A N   1 
ATOM   2669  C CA  . SER A 1 351 ? -2.982  3.198   49.289  1.00 41.39  ? 370 SER A CA  1 
ATOM   2670  C C   . SER A 1 351 ? -3.269  1.705   49.412  1.00 41.07  ? 370 SER A C   1 
ATOM   2671  O O   . SER A 1 351 ? -2.493  0.849   48.966  1.00 41.66  ? 370 SER A O   1 
ATOM   2672  C CB  . SER A 1 351 ? -3.722  3.818   48.112  1.00 43.99  ? 370 SER A CB  1 
ATOM   2673  O OG  . SER A 1 351 ? -3.235  3.305   46.890  1.00 46.46  ? 370 SER A OG  1 
ATOM   2674  N N   . ARG A 1 352 ? -4.401  1.425   50.067  1.00 40.76  ? 371 ARG A N   1 
ATOM   2675  C CA  . ARG A 1 352 ? -4.913  0.078   50.247  1.00 40.44  ? 371 ARG A CA  1 
ATOM   2676  C C   . ARG A 1 352 ? -6.432  0.118   50.192  1.00 40.91  ? 371 ARG A C   1 
ATOM   2677  O O   . ARG A 1 352 ? -7.056  0.963   50.845  1.00 40.41  ? 371 ARG A O   1 
ATOM   2678  C CB  . ARG A 1 352 ? -4.449  -0.512  51.594  1.00 38.67  ? 371 ARG A CB  1 
ATOM   2679  C CG  . ARG A 1 352 ? -4.628  -2.027  51.727  1.00 38.11  ? 371 ARG A CG  1 
ATOM   2680  C CD  . ARG A 1 352 ? -3.530  -2.800  50.922  1.00 39.20  ? 371 ARG A CD  1 
ATOM   2681  N NE  . ARG A 1 352 ? -3.497  -4.229  51.253  1.00 38.84  ? 371 ARG A NE  1 
ATOM   2682  C CZ  . ARG A 1 352 ? -3.001  -4.730  52.384  1.00 37.18  ? 371 ARG A CZ  1 
ATOM   2683  N NH1 . ARG A 1 352 ? -2.383  -3.952  53.298  1.00 35.68  ? 371 ARG A NH1 1 
ATOM   2684  N NH2 . ARG A 1 352 ? -3.127  -6.029  52.617  1.00 37.52  ? 371 ARG A NH2 1 
ATOM   2685  N N   . GLU A 1 353 ? -7.004  -0.829  49.447  1.00 41.93  ? 372 GLU A N   1 
ATOM   2686  C CA  . GLU A 1 353 ? -8.434  -1.074  49.397  1.00 42.63  ? 372 GLU A CA  1 
ATOM   2687  C C   . GLU A 1 353 ? -8.835  -2.269  50.246  1.00 41.51  ? 372 GLU A C   1 
ATOM   2688  O O   . GLU A 1 353 ? -8.233  -3.342  50.135  1.00 41.55  ? 372 GLU A O   1 
ATOM   2689  C CB  . GLU A 1 353 ? -8.862  -1.334  47.960  1.00 45.64  ? 372 GLU A CB  1 
ATOM   2690  C CG  . GLU A 1 353 ? -8.566  -0.164  47.104  1.00 48.22  ? 372 GLU A CG  1 
ATOM   2691  C CD  . GLU A 1 353 ? -9.280  1.084   47.615  1.00 48.77  ? 372 GLU A CD  1 
ATOM   2692  O OE1 . GLU A 1 353 ? -10.457 0.942   48.039  1.00 48.45  ? 372 GLU A OE1 1 
ATOM   2693  O OE2 . GLU A 1 353 ? -8.664  2.183   47.615  1.00 49.69  ? 372 GLU A OE2 1 
ATOM   2694  N N   . TYR A 1 354 ? -9.886  -2.094  51.038  1.00 43.79  ? 373 TYR A N   1 
ATOM   2695  C CA  . TYR A 1 354 ? -10.466 -3.148  51.843  1.00 42.97  ? 373 TYR A CA  1 
ATOM   2696  C C   . TYR A 1 354 ? -11.933 -3.309  51.456  1.00 44.30  ? 373 TYR A C   1 
ATOM   2697  O O   . TYR A 1 354 ? -12.519 -2.447  50.790  1.00 46.01  ? 373 TYR A O   1 
ATOM   2698  C CB  . TYR A 1 354 ? -10.346 -2.823  53.329  1.00 40.74  ? 373 TYR A CB  1 
ATOM   2699  C CG  . TYR A 1 354 ? -8.964  -2.917  53.947  1.00 39.08  ? 373 TYR A CG  1 
ATOM   2700  C CD1 . TYR A 1 354 ? -8.006  -1.914  53.793  1.00 38.92  ? 373 TYR A CD1 1 
ATOM   2701  C CD2 . TYR A 1 354 ? -8.633  -3.985  54.760  1.00 38.03  ? 373 TYR A CD2 1 
ATOM   2702  C CE1 . TYR A 1 354 ? -6.738  -2.026  54.407  1.00 37.84  ? 373 TYR A CE1 1 
ATOM   2703  C CE2 . TYR A 1 354 ? -7.374  -4.075  55.382  1.00 37.11  ? 373 TYR A CE2 1 
ATOM   2704  C CZ  . TYR A 1 354 ? -6.441  -3.122  55.198  1.00 36.66  ? 373 TYR A CZ  1 
ATOM   2705  O OH  . TYR A 1 354 ? -5.229  -3.300  55.855  1.00 35.82  ? 373 TYR A OH  1 
ATOM   2706  N N   . LYS A 1 355 ? -12.531 -4.449  51.841  1.00 41.09  ? 374 LYS A N   1 
ATOM   2707  C CA  . LYS A 1 355 ? -13.914 -4.705  51.426  1.00 43.52  ? 374 LYS A CA  1 
ATOM   2708  C C   . LYS A 1 355 ? -14.836 -3.568  51.853  1.00 43.81  ? 374 LYS A C   1 
ATOM   2709  O O   . LYS A 1 355 ? -15.764 -3.235  51.120  1.00 45.98  ? 374 LYS A O   1 
ATOM   2710  C CB  . LYS A 1 355 ? -14.402 -6.064  51.964  1.00 44.73  ? 374 LYS A CB  1 
ATOM   2711  N N   . HIS A 1 356 ? -14.553 -2.905  52.980  1.00 41.09  ? 375 HIS A N   1 
ATOM   2712  C CA  . HIS A 1 356 ? -15.423 -1.842  53.476  1.00 42.63  ? 375 HIS A CA  1 
ATOM   2713  C C   . HIS A 1 356 ? -14.685 -0.551  53.798  1.00 42.12  ? 375 HIS A C   1 
ATOM   2714  O O   . HIS A 1 356 ? -15.206 0.262   54.557  1.00 42.96  ? 375 HIS A O   1 
ATOM   2715  C CB  . HIS A 1 356 ? -16.191 -2.308  54.719  1.00 43.01  ? 375 HIS A CB  1 
ATOM   2716  C CG  . HIS A 1 356 ? -16.880 -3.621  54.531  1.00 43.98  ? 375 HIS A CG  1 
ATOM   2717  N ND1 . HIS A 1 356 ? -17.842 -3.813  53.563  1.00 46.54  ? 375 HIS A ND1 1 
ATOM   2718  C CD2 . HIS A 1 356 ? -16.715 -4.815  55.144  1.00 43.52  ? 375 HIS A CD2 1 
ATOM   2719  C CE1 . HIS A 1 356 ? -18.253 -5.066  53.600  1.00 46.85  ? 375 HIS A CE1 1 
ATOM   2720  N NE2 . HIS A 1 356 ? -17.570 -5.704  54.534  1.00 45.44  ? 375 HIS A NE2 1 
ATOM   2721  N N   . ALA A 1 357 ? -13.522 -0.313  53.207  1.00 42.04  ? 376 ALA A N   1 
ATOM   2722  C CA  . ALA A 1 357 ? -12.818 0.919   53.521  1.00 41.90  ? 376 ALA A CA  1 
ATOM   2723  C C   . ALA A 1 357 ? -11.702 1.155   52.524  1.00 41.94  ? 376 ALA A C   1 
ATOM   2724  O O   . ALA A 1 357 ? -11.140 0.217   51.968  1.00 41.13  ? 376 ALA A O   1 
ATOM   2725  C CB  . ALA A 1 357 ? -12.251 0.866   54.952  1.00 40.98  ? 376 ALA A CB  1 
ATOM   2726  N N   . SER A 1 358 ? -11.370 2.419   52.330  1.00 42.41  ? 377 SER A N   1 
ATOM   2727  C CA  . SER A 1 358 ? -10.275 2.821   51.468  1.00 42.45  ? 377 SER A CA  1 
ATOM   2728  C C   . SER A 1 358 ? -9.292  3.664   52.251  1.00 41.77  ? 377 SER A C   1 
ATOM   2729  O O   . SER A 1 358 ? -9.688  4.528   53.042  1.00 43.08  ? 377 SER A O   1 
ATOM   2730  C CB  . SER A 1 358 ? -10.774 3.622   50.294  1.00 45.24  ? 377 SER A CB  1 
ATOM   2731  O OG  . SER A 1 358 ? -11.622 2.822   49.489  1.00 46.44  ? 377 SER A OG  1 
ATOM   2732  N N   . VAL A 1 359 ? -8.011  3.429   52.026  1.00 42.05  ? 378 VAL A N   1 
ATOM   2733  C CA  . VAL A 1 359 ? -6.972  4.079   52.806  1.00 41.51  ? 378 VAL A CA  1 
ATOM   2734  C C   . VAL A 1 359 ? -5.990  4.757   51.867  1.00 42.51  ? 378 VAL A C   1 
ATOM   2735  O O   . VAL A 1 359 ? -5.556  4.174   50.872  1.00 41.93  ? 378 VAL A O   1 
ATOM   2736  C CB  . VAL A 1 359 ? -6.230  3.080   53.729  1.00 38.79  ? 378 VAL A CB  1 
ATOM   2737  C CG1 . VAL A 1 359 ? -5.082  3.754   54.407  1.00 38.32  ? 378 VAL A CG1 1 
ATOM   2738  C CG2 . VAL A 1 359 ? -7.154  2.548   54.772  1.00 38.84  ? 378 VAL A CG2 1 
ATOM   2739  N N   . ARG A 1 360 ? -5.595  5.961   52.228  1.00 40.87  ? 379 ARG A N   1 
ATOM   2740  C CA  . ARG A 1 360 ? -4.569  6.706   51.524  1.00 42.47  ? 379 ARG A CA  1 
ATOM   2741  C C   . ARG A 1 360 ? -3.715  7.411   52.560  1.00 41.88  ? 379 ARG A C   1 
ATOM   2742  O O   . ARG A 1 360 ? -4.242  7.956   53.530  1.00 42.66  ? 379 ARG A O   1 
ATOM   2743  C CB  . ARG A 1 360 ? -5.206  7.713   50.577  1.00 47.31  ? 379 ARG A CB  1 
ATOM   2744  C CG  . ARG A 1 360 ? -5.526  7.122   49.234  1.00 49.54  ? 379 ARG A CG  1 
ATOM   2745  C CD  . ARG A 1 360 ? -4.925  7.979   48.146  1.00 52.45  ? 379 ARG A CD  1 
ATOM   2746  N NE  . ARG A 1 360 ? -5.184  7.389   46.844  1.00 53.61  ? 379 ARG A NE  1 
ATOM   2747  C CZ  . ARG A 1 360 ? -4.259  7.184   45.914  1.00 54.47  ? 379 ARG A CZ  1 
ATOM   2748  N NH1 . ARG A 1 360 ? -2.975  7.456   46.146  1.00 53.98  ? 379 ARG A NH1 1 
ATOM   2749  N NH2 . ARG A 1 360 ? -4.633  6.723   44.710  1.00 55.98  ? 379 ARG A NH2 1 
ATOM   2750  N N   . VAL A 1 361 ? -2.401  7.388   52.365  1.00 40.53  ? 380 VAL A N   1 
ATOM   2751  C CA  . VAL A 1 361 ? -1.493  8.040   53.298  1.00 41.02  ? 380 VAL A CA  1 
ATOM   2752  C C   . VAL A 1 361 ? -0.275  8.570   52.556  1.00 42.00  ? 380 VAL A C   1 
ATOM   2753  O O   . VAL A 1 361 ? 0.312   7.883   51.719  1.00 40.72  ? 380 VAL A O   1 
ATOM   2754  C CB  . VAL A 1 361 ? -1.089  7.090   54.442  1.00 38.66  ? 380 VAL A CB  1 
ATOM   2755  C CG1 . VAL A 1 361 ? -0.384  5.856   53.921  1.00 35.34  ? 380 VAL A CG1 1 
ATOM   2756  C CG2 . VAL A 1 361 ? -0.222  7.807   55.459  1.00 39.40  ? 380 VAL A CG2 1 
ATOM   2757  N N   . ASP A 1 362 ? 0.086   9.808   52.845  1.00 42.95  ? 381 ASP A N   1 
ATOM   2758  C CA  . ASP A 1 362 ? 1.304   10.443  52.344  1.00 44.40  ? 381 ASP A CA  1 
ATOM   2759  C C   . ASP A 1 362 ? 2.284   10.552  53.514  1.00 43.23  ? 381 ASP A C   1 
ATOM   2760  O O   . ASP A 1 362 ? 2.030   11.266  54.487  1.00 45.56  ? 381 ASP A O   1 
ATOM   2761  C CB  . ASP A 1 362 ? 0.974   11.805  51.740  1.00 49.04  ? 381 ASP A CB  1 
ATOM   2762  C CG  . ASP A 1 362 ? 2.096   12.371  50.881  1.00 51.45  ? 381 ASP A CG  1 
ATOM   2763  O OD1 . ASP A 1 362 ? 3.276   12.159  51.181  1.00 50.04  ? 381 ASP A OD1 1 
ATOM   2764  O OD2 . ASP A 1 362 ? 1.798   13.062  49.894  1.00 54.65  ? 381 ASP A OD2 1 
ATOM   2765  N N   . LEU A 1 363 ? 3.375   9.801   53.445  1.00 46.12  ? 382 LEU A N   1 
ATOM   2766  C CA  . LEU A 1 363 ? 4.334   9.809   54.538  1.00 43.82  ? 382 LEU A CA  1 
ATOM   2767  C C   . LEU A 1 363 ? 5.114   11.105  54.547  1.00 47.27  ? 382 LEU A C   1 
ATOM   2768  O O   . LEU A 1 363 ? 5.570   11.547  55.600  1.00 45.65  ? 382 LEU A O   1 
ATOM   2769  C CB  . LEU A 1 363 ? 5.289   8.621   54.411  1.00 39.42  ? 382 LEU A CB  1 
ATOM   2770  C CG  . LEU A 1 363 ? 4.669   7.215   54.405  1.00 36.47  ? 382 LEU A CG  1 
ATOM   2771  C CD1 . LEU A 1 363 ? 5.732   6.196   54.182  1.00 35.20  ? 382 LEU A CD1 1 
ATOM   2772  C CD2 . LEU A 1 363 ? 3.916   6.958   55.710  1.00 34.77  ? 382 LEU A CD2 1 
ATOM   2773  N N   . GLU A 1 364 ? 5.281   11.719  53.380  1.00 41.68  ? 383 GLU A N   1 
ATOM   2774  C CA  . GLU A 1 364 ? 6.029   12.967  53.304  1.00 45.72  ? 383 GLU A CA  1 
ATOM   2775  C C   . GLU A 1 364 ? 5.218   14.123  53.869  1.00 49.99  ? 383 GLU A C   1 
ATOM   2776  O O   . GLU A 1 364 ? 5.679   14.822  54.763  1.00 49.49  ? 383 GLU A O   1 
ATOM   2777  C CB  . GLU A 1 364 ? 6.451   13.242  51.861  1.00 48.79  ? 383 GLU A CB  1 
ATOM   2778  C CG  . GLU A 1 364 ? 7.133   14.592  51.666  1.00 51.84  ? 383 GLU A CG  1 
ATOM   2779  C CD  . GLU A 1 364 ? 7.832   14.749  50.325  1.00 54.65  ? 383 GLU A CD  1 
ATOM   2780  O OE1 . GLU A 1 364 ? 7.328   14.248  49.305  1.00 54.79  ? 383 GLU A OE1 1 
ATOM   2781  O OE2 . GLU A 1 364 ? 8.898   15.382  50.290  1.00 56.07  ? 383 GLU A OE2 1 
ATOM   2782  N N   . SER A 1 365 ? 3.999   14.336  53.381  1.00 49.29  ? 384 SER A N   1 
ATOM   2783  C CA  . SER A 1 365 ? 3.195   15.443  53.902  1.00 52.30  ? 384 SER A CA  1 
ATOM   2784  C C   . SER A 1 365 ? 2.494   15.110  55.209  1.00 48.47  ? 384 SER A C   1 
ATOM   2785  O O   . SER A 1 365 ? 1.976   16.023  55.862  1.00 47.83  ? 384 SER A O   1 
ATOM   2786  C CB  . SER A 1 365 ? 2.137   15.878  52.885  1.00 52.78  ? 384 SER A CB  1 
ATOM   2787  O OG  . SER A 1 365 ? 1.225   14.837  52.590  1.00 50.05  ? 384 SER A OG  1 
ATOM   2788  N N   . LYS A 1 366 ? 2.443   13.833  55.583  1.00 51.41  ? 385 LYS A N   1 
ATOM   2789  C CA  . LYS A 1 366 ? 1.800   13.339  56.790  1.00 48.40  ? 385 LYS A CA  1 
ATOM   2790  C C   . LYS A 1 366 ? 0.279   13.372  56.707  1.00 50.09  ? 385 LYS A C   1 
ATOM   2791  O O   . LYS A 1 366 ? -0.388  13.239  57.737  1.00 48.03  ? 385 LYS A O   1 
ATOM   2792  C CB  . LYS A 1 366 ? 2.255   14.117  58.032  1.00 46.83  ? 385 LYS A CB  1 
ATOM   2793  C CG  . LYS A 1 366 ? 2.784   13.274  59.219  1.00 43.74  ? 385 LYS A CG  1 
ATOM   2794  C CD  . LYS A 1 366 ? 4.196   12.760  59.028  1.00 39.40  ? 385 LYS A CD  1 
ATOM   2795  C CE  . LYS A 1 366 ? 4.616   11.884  60.256  1.00 36.73  ? 385 LYS A CE  1 
ATOM   2796  N NZ  . LYS A 1 366 ? 4.949   12.660  61.517  1.00 36.04  ? 385 LYS A NZ  1 
ATOM   2797  N N   . GLU A 1 367 ? -0.298  13.537  55.516  1.00 49.56  ? 386 GLU A N   1 
ATOM   2798  C CA  . GLU A 1 367 ? -1.749  13.444  55.396  1.00 49.45  ? 386 GLU A CA  1 
ATOM   2799  C C   . GLU A 1 367 ? -2.217  11.997  55.226  1.00 46.40  ? 386 GLU A C   1 
ATOM   2800  O O   . GLU A 1 367 ? -1.467  11.095  54.828  1.00 44.83  ? 386 GLU A O   1 
ATOM   2801  C CB  . GLU A 1 367 ? -2.256  14.246  54.220  1.00 52.19  ? 386 GLU A CB  1 
ATOM   2802  C CG  . GLU A 1 367 ? -2.826  15.564  54.686  1.00 54.19  ? 386 GLU A CG  1 
ATOM   2803  C CD  . GLU A 1 367 ? -1.726  16.557  55.055  1.00 56.82  ? 386 GLU A CD  1 
ATOM   2804  O OE1 . GLU A 1 367 ? -1.631  16.947  56.258  1.00 55.49  ? 386 GLU A OE1 1 
ATOM   2805  O OE2 . GLU A 1 367 ? -0.944  16.908  54.136  1.00 59.73  ? 386 GLU A OE2 1 
ATOM   2806  N N   . ALA A 1 368 ? -3.493  11.788  55.530  1.00 44.39  ? 387 ALA A N   1 
ATOM   2807  C CA  . ALA A 1 368 ? -4.055  10.450  55.505  1.00 41.90  ? 387 ALA A CA  1 
ATOM   2808  C C   . ALA A 1 368 ? -5.565  10.552  55.347  1.00 42.35  ? 387 ALA A C   1 
ATOM   2809  O O   . ALA A 1 368 ? -6.186  11.464  55.891  1.00 42.87  ? 387 ALA A O   1 
ATOM   2810  C CB  . ALA A 1 368 ? -3.703  9.677   56.780  1.00 40.25  ? 387 ALA A CB  1 
ATOM   2811  N N   . GLU A 1 369 ? -6.146  9.624   54.610  1.00 42.94  ? 388 GLU A N   1 
ATOM   2812  C CA  . GLU A 1 369 ? -7.592  9.537   54.476  1.00 43.53  ? 388 GLU A CA  1 
ATOM   2813  C C   . GLU A 1 369 ? -7.981  8.094   54.738  1.00 40.74  ? 388 GLU A C   1 
ATOM   2814  O O   . GLU A 1 369 ? -7.250  7.187   54.346  1.00 39.19  ? 388 GLU A O   1 
ATOM   2815  C CB  . GLU A 1 369 ? -8.071  9.999   53.080  1.00 46.31  ? 388 GLU A CB  1 
ATOM   2816  N N   . ILE A 1 370 ? -9.095  7.894   55.437  1.00 42.00  ? 389 ILE A N   1 
ATOM   2817  C CA  . ILE A 1 370 ? -9.777  6.611   55.482  1.00 40.75  ? 389 ILE A CA  1 
ATOM   2818  C C   . ILE A 1 370 ? -11.242 6.865   55.171  1.00 41.92  ? 389 ILE A C   1 
ATOM   2819  O O   . ILE A 1 370 ? -11.942 7.465   55.994  1.00 42.19  ? 389 ILE A O   1 
ATOM   2820  C CB  . ILE A 1 370 ? -9.640  5.903   56.841  1.00 39.26  ? 389 ILE A CB  1 
ATOM   2821  C CG1 . ILE A 1 370 ? -8.172  5.750   57.232  1.00 38.56  ? 389 ILE A CG1 1 
ATOM   2822  C CG2 . ILE A 1 370 ? -10.310 4.525   56.796  1.00 38.65  ? 389 ILE A CG2 1 
ATOM   2823  C CD1 . ILE A 1 370 ? -7.940  5.070   58.577  1.00 37.22  ? 389 ILE A CD1 1 
ATOM   2824  N N   . ARG A 1 371 ? -11.708 6.401   53.997  1.00 43.63  ? 390 ARG A N   1 
ATOM   2825  C CA  . ARG A 1 371 ? -13.131 6.401   53.633  1.00 44.74  ? 390 ARG A CA  1 
ATOM   2826  C C   . ARG A 1 371 ? -13.714 5.038   54.020  1.00 43.58  ? 390 ARG A C   1 
ATOM   2827  O O   . ARG A 1 371 ? -13.412 4.007   53.398  1.00 43.87  ? 390 ARG A O   1 
ATOM   2828  C CB  . ARG A 1 371 ? -13.339 6.686   52.144  1.00 47.23  ? 390 ARG A CB  1 
ATOM   2829  N N   . TRP A 1 372 ? -14.491 5.014   55.089  1.00 44.34  ? 391 TRP A N   1 
ATOM   2830  C CA  . TRP A 1 372 ? -15.294 3.859   55.450  1.00 44.10  ? 391 TRP A CA  1 
ATOM   2831  C C   . TRP A 1 372 ? -16.528 3.805   54.567  1.00 45.67  ? 391 TRP A C   1 
ATOM   2832  O O   . TRP A 1 372 ? -17.050 4.837   54.154  1.00 46.49  ? 391 TRP A O   1 
ATOM   2833  C CB  . TRP A 1 372 ? -15.683 3.971   56.917  1.00 42.51  ? 391 TRP A CB  1 
ATOM   2834  C CG  . TRP A 1 372 ? -14.514 4.185   57.885  1.00 41.15  ? 391 TRP A CG  1 
ATOM   2835  C CD1 . TRP A 1 372 ? -14.069 5.389   58.398  1.00 40.88  ? 391 TRP A CD1 1 
ATOM   2836  C CD2 . TRP A 1 372 ? -13.659 3.170   58.470  1.00 39.56  ? 391 TRP A CD2 1 
ATOM   2837  N NE1 . TRP A 1 372 ? -12.996 5.183   59.244  1.00 39.83  ? 391 TRP A NE1 1 
ATOM   2838  C CE2 . TRP A 1 372 ? -12.727 3.838   59.309  1.00 38.62  ? 391 TRP A CE2 1 
ATOM   2839  C CE3 . TRP A 1 372 ? -13.582 1.787   58.353  1.00 39.01  ? 391 TRP A CE3 1 
ATOM   2840  C CZ2 . TRP A 1 372 ? -11.750 3.160   60.020  1.00 36.99  ? 391 TRP A CZ2 1 
ATOM   2841  C CZ3 . TRP A 1 372 ? -12.622 1.112   59.074  1.00 37.60  ? 391 TRP A CZ3 1 
ATOM   2842  C CH2 . TRP A 1 372 ? -11.706 1.794   59.884  1.00 36.57  ? 391 TRP A CH2 1 
ATOM   2843  N N   . ARG A 1 373 ? -16.992 2.596   54.259  1.00 47.11  ? 392 ARG A N   1 
ATOM   2844  C CA  . ARG A 1 373 ? -18.217 2.466   53.465  1.00 49.38  ? 392 ARG A CA  1 
ATOM   2845  C C   . ARG A 1 373 ? -19.073 1.206   53.603  1.00 50.06  ? 392 ARG A C   1 
ATOM   2846  O O   . ARG A 1 373 ? -18.950 0.458   54.599  1.00 49.01  ? 392 ARG A O   1 
ATOM   2847  C CB  . ARG A 1 373 ? -17.838 2.624   51.985  1.00 51.45  ? 392 ARG A CB  1 
ATOM   2848  C CG  . ARG A 1 373 ? -16.721 1.736   51.561  1.00 52.25  ? 392 ARG A CG  1 
ATOM   2849  C CD  . ARG A 1 373 ? -16.877 1.249   50.096  1.00 54.34  ? 392 ARG A CD  1 
ATOM   2850  N NE  . ARG A 1 373 ? -15.604 0.635   49.728  1.00 54.09  ? 392 ARG A NE  1 
ATOM   2851  C CZ  . ARG A 1 373 ? -14.463 1.317   49.633  1.00 53.97  ? 392 ARG A CZ  1 
ATOM   2852  N NH1 . ARG A 1 373 ? -14.459 2.652   49.612  1.00 54.63  ? 392 ARG A NH1 1 
ATOM   2853  N NH2 . ARG A 1 373 ? -13.301 0.646   49.564  1.00 53.01  ? 392 ARG A NH2 1 
ATOM   2854  N N   . SER B 1 19  ? 1.517   11.800  96.566  1.00 44.72  ? 38  SER B N   1 
ATOM   2855  C CA  . SER B 1 19  ? 0.178   11.986  97.179  1.00 44.98  ? 38  SER B CA  1 
ATOM   2856  C C   . SER B 1 19  ? 0.227   11.348  98.557  1.00 43.13  ? 38  SER B C   1 
ATOM   2857  O O   . SER B 1 19  ? -0.629  11.585  99.418  1.00 43.92  ? 38  SER B O   1 
ATOM   2858  C CB  . SER B 1 19  ? -0.973  11.378  96.364  1.00 46.69  ? 38  SER B CB  1 
ATOM   2859  O OG  . SER B 1 19  ? -1.082  9.981   96.518  1.00 46.66  ? 38  SER B OG  1 
ATOM   2860  N N   . HIS B 1 20  ? 1.225   10.488  98.742  1.00 40.32  ? 39  HIS B N   1 
ATOM   2861  C CA  . HIS B 1 20  ? 1.619   10.073  100.084 1.00 38.89  ? 39  HIS B CA  1 
ATOM   2862  C C   . HIS B 1 20  ? 2.715   10.982  100.642 1.00 37.30  ? 39  HIS B C   1 
ATOM   2863  O O   . HIS B 1 20  ? 3.133   10.811  101.790 1.00 36.61  ? 39  HIS B O   1 
ATOM   2864  C CB  . HIS B 1 20  ? 2.027   8.596   100.075 1.00 38.35  ? 39  HIS B CB  1 
ATOM   2865  C CG  . HIS B 1 20  ? 3.211   8.284   99.220  1.00 37.58  ? 39  HIS B CG  1 
ATOM   2866  N ND1 . HIS B 1 20  ? 4.422   7.892   99.754  1.00 36.56  ? 39  HIS B ND1 1 
ATOM   2867  C CD2 . HIS B 1 20  ? 3.369   8.258   97.877  1.00 38.45  ? 39  HIS B CD2 1 
ATOM   2868  C CE1 . HIS B 1 20  ? 5.282   7.663   98.777  1.00 36.13  ? 39  HIS B CE1 1 
ATOM   2869  N NE2 . HIS B 1 20  ? 4.665   7.878   97.629  1.00 36.99  ? 39  HIS B NE2 1 
ATOM   2870  N N   . TYR B 1 21  ? 3.129   11.976  99.862  1.00 35.71  ? 40  TYR B N   1 
ATOM   2871  C CA  . TYR B 1 21  ? 4.090   12.980  100.251 1.00 34.89  ? 40  TYR B CA  1 
ATOM   2872  C C   . TYR B 1 21  ? 3.548   13.895  101.362 1.00 35.62  ? 40  TYR B C   1 
ATOM   2873  O O   . TYR B 1 21  ? 2.339   14.021  101.546 1.00 36.98  ? 40  TYR B O   1 
ATOM   2874  C CB  . TYR B 1 21  ? 4.454   13.812  99.020  1.00 34.97  ? 40  TYR B CB  1 
ATOM   2875  C CG  . TYR B 1 21  ? 5.397   13.173  98.019  1.00 34.09  ? 40  TYR B CG  1 
ATOM   2876  C CD1 . TYR B 1 21  ? 5.690   11.806  98.048  1.00 33.55  ? 40  TYR B CD1 1 
ATOM   2877  C CD2 . TYR B 1 21  ? 6.008   13.944  97.036  1.00 34.23  ? 40  TYR B CD2 1 
ATOM   2878  C CE1 . TYR B 1 21  ? 6.595   11.235  97.128  1.00 32.90  ? 40  TYR B CE1 1 
ATOM   2879  C CE2 . TYR B 1 21  ? 6.878   13.364  96.097  1.00 34.04  ? 40  TYR B CE2 1 
ATOM   2880  C CZ  . TYR B 1 21  ? 7.180   12.015  96.161  1.00 33.02  ? 40  TYR B CZ  1 
ATOM   2881  O OH  . TYR B 1 21  ? 8.073   11.473  95.260  1.00 33.19  ? 40  TYR B OH  1 
ATOM   2882  N N   . PRO B 1 22  ? 4.445   14.516  102.144 1.00 35.00  ? 41  PRO B N   1 
ATOM   2883  C CA  . PRO B 1 22  ? 4.003   15.576  103.042 1.00 35.88  ? 41  PRO B CA  1 
ATOM   2884  C C   . PRO B 1 22  ? 3.329   16.650  102.222 1.00 36.68  ? 41  PRO B C   1 
ATOM   2885  O O   . PRO B 1 22  ? 3.716   16.934  101.082 1.00 36.58  ? 41  PRO B O   1 
ATOM   2886  C CB  . PRO B 1 22  ? 5.289   16.105  103.668 1.00 35.07  ? 41  PRO B CB  1 
ATOM   2887  C CG  . PRO B 1 22  ? 6.317   15.109  103.388 1.00 34.03  ? 41  PRO B CG  1 
ATOM   2888  C CD  . PRO B 1 22  ? 5.913   14.401  102.125 1.00 33.93  ? 41  PRO B CD  1 
ATOM   2889  N N   . GLU B 1 23  ? 2.326   17.256  102.810 1.00 38.18  ? 42  GLU B N   1 
ATOM   2890  C CA  . GLU B 1 23  ? 1.731   18.397  102.142 1.00 39.02  ? 42  GLU B CA  1 
ATOM   2891  C C   . GLU B 1 23  ? 2.714   19.559  102.059 1.00 38.90  ? 42  GLU B C   1 
ATOM   2892  O O   . GLU B 1 23  ? 3.288   19.987  103.066 1.00 39.05  ? 42  GLU B O   1 
ATOM   2893  C CB  . GLU B 1 23  ? 0.486   18.844  102.864 1.00 40.68  ? 42  GLU B CB  1 
ATOM   2894  C CG  . GLU B 1 23  ? -0.189  19.802  102.036 1.00 42.72  ? 42  GLU B CG  1 
ATOM   2895  C CD  . GLU B 1 23  ? -1.582  19.963  102.442 1.00 44.68  ? 42  GLU B CD  1 
ATOM   2896  O OE1 . GLU B 1 23  ? -2.240  18.917  102.660 1.00 45.39  ? 42  GLU B OE1 1 
ATOM   2897  O OE2 . GLU B 1 23  ? -2.057  21.114  102.572 1.00 46.77  ? 42  GLU B OE2 1 
ATOM   2898  N N   . PHE B 1 24  ? 2.906   20.054  100.843 1.00 35.66  ? 43  PHE B N   1 
ATOM   2899  C CA  . PHE B 1 24  ? 3.938   21.023  100.520 1.00 35.20  ? 43  PHE B CA  1 
ATOM   2900  C C   . PHE B 1 24  ? 3.290   22.323  100.087 1.00 36.56  ? 43  PHE B C   1 
ATOM   2901  O O   . PHE B 1 24  ? 2.254   22.315  99.397  1.00 37.79  ? 43  PHE B O   1 
ATOM   2902  C CB  . PHE B 1 24  ? 4.821   20.535  99.419  1.00 34.67  ? 43  PHE B CB  1 
ATOM   2903  C CG  . PHE B 1 24  ? 5.861   21.509  98.989  1.00 34.28  ? 43  PHE B CG  1 
ATOM   2904  C CD1 . PHE B 1 24  ? 7.122   21.501  99.583  1.00 33.55  ? 43  PHE B CD1 1 
ATOM   2905  C CD2 . PHE B 1 24  ? 5.619   22.398  97.976  1.00 35.66  ? 43  PHE B CD2 1 
ATOM   2906  C CE1 . PHE B 1 24  ? 8.111   22.385  99.163  1.00 34.01  ? 43  PHE B CE1 1 
ATOM   2907  C CE2 . PHE B 1 24  ? 6.606   23.277  97.562  1.00 35.76  ? 43  PHE B CE2 1 
ATOM   2908  C CZ  . PHE B 1 24  ? 7.832   23.278  98.136  1.00 35.09  ? 43  PHE B CZ  1 
ATOM   2909  N N   . SER B 1 25  ? 3.907   23.417  100.497 1.00 36.51  ? 44  SER B N   1 
ATOM   2910  C CA  . SER B 1 25  ? 3.376   24.746  100.184 1.00 37.96  ? 44  SER B CA  1 
ATOM   2911  C C   . SER B 1 25  ? 4.533   25.709  100.015 1.00 37.71  ? 44  SER B C   1 
ATOM   2912  O O   . SER B 1 25  ? 5.615   25.435  100.553 1.00 36.98  ? 44  SER B O   1 
ATOM   2913  C CB  . SER B 1 25  ? 2.463   25.225  101.246 1.00 39.44  ? 44  SER B CB  1 
ATOM   2914  O OG  . SER B 1 25  ? 3.149   26.068  102.159 1.00 40.82  ? 44  SER B OG  1 
ATOM   2915  N N   . TRP B 1 26  ? 4.299   26.758  99.258  1.00 37.84  ? 45  TRP B N   1 
ATOM   2916  C CA  . TRP B 1 26  ? 5.272   27.810  99.067  1.00 38.16  ? 45  TRP B CA  1 
ATOM   2917  C C   . TRP B 1 26  ? 4.982   29.039  99.936  1.00 38.84  ? 45  TRP B C   1 
ATOM   2918  O O   . TRP B 1 26  ? 5.719   30.030  99.870  1.00 39.65  ? 45  TRP B O   1 
ATOM   2919  C CB  . TRP B 1 26  ? 5.278   28.194  97.610  1.00 39.08  ? 45  TRP B CB  1 
ATOM   2920  C CG  . TRP B 1 26  ? 5.897   27.231  96.624  1.00 38.43  ? 45  TRP B CG  1 
ATOM   2921  C CD1 . TRP B 1 26  ? 5.251   26.610  95.580  1.00 39.07  ? 45  TRP B CD1 1 
ATOM   2922  C CD2 . TRP B 1 26  ? 7.289   26.857  96.506  1.00 37.55  ? 45  TRP B CD2 1 
ATOM   2923  N NE1 . TRP B 1 26  ? 6.145   25.881  94.846  1.00 38.68  ? 45  TRP B NE1 1 
ATOM   2924  C CE2 . TRP B 1 26  ? 7.398   26.013  95.373  1.00 37.90  ? 45  TRP B CE2 1 
ATOM   2925  C CE3 . TRP B 1 26  ? 8.443   27.150  97.242  1.00 37.25  ? 45  TRP B CE3 1 
ATOM   2926  C CZ2 . TRP B 1 26  ? 8.603   25.469  94.954  1.00 37.72  ? 45  TRP B CZ2 1 
ATOM   2927  C CZ3 . TRP B 1 26  ? 9.656   26.579  96.840  1.00 37.08  ? 45  TRP B CZ3 1 
ATOM   2928  C CH2 . TRP B 1 26  ? 9.724   25.752  95.703  1.00 37.45  ? 45  TRP B CH2 1 
ATOM   2929  N N   . ASP B 1 27  ? 3.851   29.023  100.654 1.00 39.20  ? 46  ASP B N   1 
ATOM   2930  C CA  . ASP B 1 27  ? 3.434   30.201  101.471 1.00 40.52  ? 46  ASP B CA  1 
ATOM   2931  C C   . ASP B 1 27  ? 4.671   30.788  102.142 1.00 39.84  ? 46  ASP B C   1 
ATOM   2932  O O   . ASP B 1 27  ? 4.789   32.025  102.138 1.00 40.97  ? 46  ASP B O   1 
ATOM   2933  C CB  . ASP B 1 27  ? 2.343   29.822  102.459 1.00 40.84  ? 46  ASP B CB  1 
ATOM   2934  C CG  . ASP B 1 27  ? 1.123   29.149  101.848 1.00 41.99  ? 46  ASP B CG  1 
ATOM   2935  O OD1 . ASP B 1 27  ? 0.474   29.780  100.989 1.00 41.31  ? 46  ASP B OD1 1 
ATOM   2936  O OD2 . ASP B 1 27  ? 0.834   27.998  102.236 1.00 44.04  ? 46  ASP B OD2 1 
ATOM   2937  N N   . THR B 1 28  ? 5.505   29.956  102.761 1.00 39.02  ? 47  THR B N   1 
ATOM   2938  C CA  . THR B 1 28  ? 6.778   30.350  103.336 1.00 38.56  ? 47  THR B CA  1 
ATOM   2939  C C   . THR B 1 28  ? 7.816   29.317  102.952 1.00 37.08  ? 47  THR B C   1 
ATOM   2940  O O   . THR B 1 28  ? 7.506   28.291  102.332 1.00 36.54  ? 47  THR B O   1 
ATOM   2941  C CB  . THR B 1 28  ? 6.704   30.421  104.857 1.00 38.76  ? 47  THR B CB  1 
ATOM   2942  O OG1 . THR B 1 28  ? 6.156   29.176  105.319 1.00 38.16  ? 47  THR B OG1 1 
ATOM   2943  C CG2 . THR B 1 28  ? 5.846   31.581  105.308 1.00 40.35  ? 47  THR B CG2 1 
ATOM   2944  N N   . VAL B 1 29  ? 9.047   29.568  103.377 1.00 36.97  ? 48  VAL B N   1 
ATOM   2945  C CA  . VAL B 1 29  ? 10.190  28.673  103.219 1.00 35.77  ? 48  VAL B CA  1 
ATOM   2946  C C   . VAL B 1 29  ? 9.768   27.316  103.763 1.00 34.71  ? 48  VAL B C   1 
ATOM   2947  O O   . VAL B 1 29  ? 9.354   27.199  104.931 1.00 35.04  ? 48  VAL B O   1 
ATOM   2948  C CB  . VAL B 1 29  ? 11.420  29.232  103.940 1.00 36.17  ? 48  VAL B CB  1 
ATOM   2949  C CG1 . VAL B 1 29  ? 12.545  28.232  103.993 1.00 35.46  ? 48  VAL B CG1 1 
ATOM   2950  C CG2 . VAL B 1 29  ? 11.968  30.402  103.218 1.00 37.30  ? 48  VAL B CG2 1 
ATOM   2951  N N   . PRO B 1 30  ? 9.846   26.265  102.950 1.00 34.34  ? 49  PRO B N   1 
ATOM   2952  C CA  . PRO B 1 30  ? 9.405   24.938  103.407 1.00 33.66  ? 49  PRO B CA  1 
ATOM   2953  C C   . PRO B 1 30  ? 10.429  24.286  104.317 1.00 33.29  ? 49  PRO B C   1 
ATOM   2954  O O   . PRO B 1 30  ? 11.565  24.025  103.925 1.00 33.06  ? 49  PRO B O   1 
ATOM   2955  C CB  . PRO B 1 30  ? 9.220   24.156  102.098 1.00 33.88  ? 49  PRO B CB  1 
ATOM   2956  C CG  . PRO B 1 30  ? 9.925   24.897  101.081 1.00 34.97  ? 49  PRO B CG  1 
ATOM   2957  C CD  . PRO B 1 30  ? 10.064  26.314  101.500 1.00 35.00  ? 49  PRO B CD  1 
ATOM   2958  N N   . ILE B 1 31  ? 10.025  24.035  105.539 1.00 32.03  ? 50  ILE B N   1 
ATOM   2959  C CA  . ILE B 1 31  ? 10.933  23.611  106.597 1.00 32.04  ? 50  ILE B CA  1 
ATOM   2960  C C   . ILE B 1 31  ? 10.591  22.190  106.973 1.00 31.08  ? 50  ILE B C   1 
ATOM   2961  O O   . ILE B 1 31  ? 9.413   21.836  107.064 1.00 31.50  ? 50  ILE B O   1 
ATOM   2962  C CB  . ILE B 1 31  ? 10.795  24.526  107.828 1.00 33.52  ? 50  ILE B CB  1 
ATOM   2963  C CG1 . ILE B 1 31  ? 11.184  25.969  107.511 1.00 34.66  ? 50  ILE B CG1 1 
ATOM   2964  C CG2 . ILE B 1 31  ? 11.599  24.023  108.966 1.00 33.70  ? 50  ILE B CG2 1 
ATOM   2965  C CD1 . ILE B 1 31  ? 12.612  26.138  107.151 1.00 34.43  ? 50  ILE B CD1 1 
ATOM   2966  N N   . ALA B 1 32  ? 11.605  21.388  107.233 1.00 32.46  ? 51  ALA B N   1 
ATOM   2967  C CA  . ALA B 1 32  ? 11.414  20.077  107.862 1.00 31.63  ? 51  ALA B CA  1 
ATOM   2968  C C   . ALA B 1 32  ? 12.263  20.026  109.125 1.00 31.44  ? 51  ALA B C   1 
ATOM   2969  O O   . ALA B 1 32  ? 13.081  20.904  109.377 1.00 32.20  ? 51  ALA B O   1 
ATOM   2970  C CB  . ALA B 1 32  ? 11.777  18.919  106.910 1.00 30.86  ? 51  ALA B CB  1 
ATOM   2971  N N   . PHE B 1 33  ? 12.070  18.963  109.909 1.00 33.05  ? 52  PHE B N   1 
ATOM   2972  C CA  . PHE B 1 33  ? 12.773  18.758  111.160 1.00 32.95  ? 52  PHE B CA  1 
ATOM   2973  C C   . PHE B 1 33  ? 13.409  17.374  111.179 1.00 32.52  ? 52  PHE B C   1 
ATOM   2974  O O   . PHE B 1 33  ? 12.878  16.415  110.629 1.00 32.08  ? 52  PHE B O   1 
ATOM   2975  C CB  . PHE B 1 33  ? 11.830  18.871  112.349 1.00 33.65  ? 52  PHE B CB  1 
ATOM   2976  C CG  . PHE B 1 33  ? 11.350  20.266  112.625 1.00 34.60  ? 52  PHE B CG  1 
ATOM   2977  C CD1 . PHE B 1 33  ? 12.124  21.153  113.348 1.00 35.24  ? 52  PHE B CD1 1 
ATOM   2978  C CD2 . PHE B 1 33  ? 10.105  20.670  112.217 1.00 35.07  ? 52  PHE B CD2 1 
ATOM   2979  C CE1 . PHE B 1 33  ? 11.675  22.427  113.638 1.00 36.52  ? 52  PHE B CE1 1 
ATOM   2980  C CE2 . PHE B 1 33  ? 9.643   21.998  112.482 1.00 36.34  ? 52  PHE B CE2 1 
ATOM   2981  C CZ  . PHE B 1 33  ? 10.438  22.862  113.201 1.00 37.09  ? 52  PHE B CZ  1 
ATOM   2982  N N   . HIS B 1 34  ? 14.526  17.256  111.868 1.00 32.52  ? 53  HIS B N   1 
ATOM   2983  C CA  . HIS B 1 34  ? 15.220  15.991  111.973 1.00 32.66  ? 53  HIS B CA  1 
ATOM   2984  C C   . HIS B 1 34  ? 16.035  16.011  113.257 1.00 33.08  ? 53  HIS B C   1 
ATOM   2985  O O   . HIS B 1 34  ? 17.211  16.372  113.266 1.00 33.44  ? 53  HIS B O   1 
ATOM   2986  C CB  . HIS B 1 34  ? 16.123  15.753  110.794 1.00 33.03  ? 53  HIS B CB  1 
ATOM   2987  C CG  . HIS B 1 34  ? 16.828  14.439  110.868 1.00 33.25  ? 53  HIS B CG  1 
ATOM   2988  N ND1 . HIS B 1 34  ? 16.597  13.434  109.969 1.00 33.25  ? 53  HIS B ND1 1 
ATOM   2989  C CD2 . HIS B 1 34  ? 17.739  13.958  111.747 1.00 34.07  ? 53  HIS B CD2 1 
ATOM   2990  C CE1 . HIS B 1 34  ? 17.349  12.394  110.271 1.00 33.40  ? 53  HIS B CE1 1 
ATOM   2991  N NE2 . HIS B 1 34  ? 18.061  12.691  111.338 1.00 34.00  ? 53  HIS B NE2 1 
ATOM   2992  N N   . PHE B 1 35  ? 15.422  15.548  114.322 1.00 32.38  ? 54  PHE B N   1 
ATOM   2993  C CA  . PHE B 1 35  ? 16.166  15.501  115.563 1.00 32.99  ? 54  PHE B CA  1 
ATOM   2994  C C   . PHE B 1 35  ? 15.570  14.479  116.507 1.00 33.31  ? 54  PHE B C   1 
ATOM   2995  O O   . PHE B 1 35  ? 14.529  13.871  116.239 1.00 33.11  ? 54  PHE B O   1 
ATOM   2996  C CB  . PHE B 1 35  ? 16.162  16.876  116.216 1.00 33.02  ? 54  PHE B CB  1 
ATOM   2997  C CG  . PHE B 1 35  ? 14.823  17.288  116.654 1.00 33.14  ? 54  PHE B CG  1 
ATOM   2998  C CD1 . PHE B 1 35  ? 14.405  17.020  117.926 1.00 34.42  ? 54  PHE B CD1 1 
ATOM   2999  C CD2 . PHE B 1 35  ? 13.963  17.925  115.792 1.00 32.91  ? 54  PHE B CD2 1 
ATOM   3000  C CE1 . PHE B 1 35  ? 13.143  17.417  118.336 1.00 34.89  ? 54  PHE B CE1 1 
ATOM   3001  C CE2 . PHE B 1 35  ? 12.720  18.330  116.187 1.00 33.33  ? 54  PHE B CE2 1 
ATOM   3002  C CZ  . PHE B 1 35  ? 12.299  18.075  117.441 1.00 34.35  ? 54  PHE B CZ  1 
ATOM   3003  N N   . GLY B 1 36  ? 16.242  14.316  117.639 1.00 33.84  ? 55  GLY B N   1 
ATOM   3004  C CA  . GLY B 1 36  ? 15.705  13.573  118.778 1.00 34.48  ? 55  GLY B CA  1 
ATOM   3005  C C   . GLY B 1 36  ? 15.936  14.302  120.038 1.00 34.77  ? 55  GLY B C   1 
ATOM   3006  O O   . GLY B 1 36  ? 16.840  15.149  120.186 1.00 34.91  ? 55  GLY B O   1 
ATOM   3007  N N   . LYS B 1 37  ? 15.091  14.013  121.032 1.00 34.62  ? 56  LYS B N   1 
ATOM   3008  C CA  . LYS B 1 37  ? 15.168  14.509  122.381 1.00 35.00  ? 56  LYS B CA  1 
ATOM   3009  C C   . LYS B 1 37  ? 15.234  13.291  123.309 1.00 35.95  ? 56  LYS B C   1 
ATOM   3010  O O   . LYS B 1 37  ? 14.205  12.769  123.745 1.00 36.56  ? 56  LYS B O   1 
ATOM   3011  C CB  . LYS B 1 37  ? 13.969  15.419  122.678 1.00 35.08  ? 56  LYS B CB  1 
ATOM   3012  C CG  . LYS B 1 37  ? 14.002  15.990  124.090 1.00 35.81  ? 56  LYS B CG  1 
ATOM   3013  C CD  . LYS B 1 37  ? 12.723  16.666  124.455 1.00 36.27  ? 56  LYS B CD  1 
ATOM   3014  C CE  . LYS B 1 37  ? 12.707  16.997  125.903 1.00 36.84  ? 56  LYS B CE  1 
ATOM   3015  N NZ  . LYS B 1 37  ? 11.446  17.666  126.268 1.00 37.34  ? 56  LYS B NZ  1 
ATOM   3016  N N   A SER B 1 38  ? 16.456  12.859  123.623 0.42 37.17  ? 57  SER B N   1 
ATOM   3017  N N   B SER B 1 38  ? 16.461  12.872  123.637 0.58 36.98  ? 57  SER B N   1 
ATOM   3018  C CA  A SER B 1 38  ? 16.633  11.640  124.403 0.42 38.57  ? 57  SER B CA  1 
ATOM   3019  C CA  B SER B 1 38  ? 16.648  11.649  124.412 0.58 38.12  ? 57  SER B CA  1 
ATOM   3020  C C   A SER B 1 38  ? 16.058  11.740  125.812 0.42 39.06  ? 57  SER B C   1 
ATOM   3021  C C   B SER B 1 38  ? 16.046  11.743  125.811 0.58 38.83  ? 57  SER B C   1 
ATOM   3022  O O   A SER B 1 38  ? 15.735  10.707  126.411 0.42 39.97  ? 57  SER B O   1 
ATOM   3023  O O   B SER B 1 38  ? 15.690  10.717  126.404 0.58 39.75  ? 57  SER B O   1 
ATOM   3024  C CB  A SER B 1 38  ? 18.119  11.292  124.497 0.42 39.17  ? 57  SER B CB  1 
ATOM   3025  C CB  B SER B 1 38  ? 18.141  11.321  124.520 0.58 38.22  ? 57  SER B CB  1 
ATOM   3026  O OG  A SER B 1 38  ? 18.789  12.232  125.318 0.42 39.62  ? 57  SER B OG  1 
ATOM   3027  O OG  B SER B 1 38  ? 18.672  10.884  123.279 0.58 37.91  ? 57  SER B OG  1 
ATOM   3028  N N   . GLN B 1 39  ? 15.921  12.952  126.358 1.00 38.87  ? 58  GLN B N   1 
ATOM   3029  C CA  . GLN B 1 39  ? 15.498  13.063  127.752 1.00 40.12  ? 58  GLN B CA  1 
ATOM   3030  C C   . GLN B 1 39  ? 14.020  12.802  127.975 1.00 40.05  ? 58  GLN B C   1 
ATOM   3031  O O   . GLN B 1 39  ? 13.613  12.589  129.122 1.00 41.23  ? 58  GLN B O   1 
ATOM   3032  C CB  . GLN B 1 39  ? 15.838  14.441  128.285 1.00 41.13  ? 58  GLN B CB  1 
ATOM   3033  C CG  . GLN B 1 39  ? 17.207  14.877  127.819 1.00 41.70  ? 58  GLN B CG  1 
ATOM   3034  C CD  . GLN B 1 39  ? 17.139  15.592  126.513 1.00 41.27  ? 58  GLN B CD  1 
ATOM   3035  O OE1 . GLN B 1 39  ? 16.287  16.455  126.343 1.00 40.46  ? 58  GLN B OE1 1 
ATOM   3036  N NE2 . GLN B 1 39  ? 17.988  15.209  125.557 1.00 41.35  ? 58  GLN B NE2 1 
ATOM   3037  N N   . GLY B 1 40  ? 13.211  12.809  126.919 1.00 37.70  ? 59  GLY B N   1 
ATOM   3038  C CA  . GLY B 1 40  ? 11.790  12.581  127.073 1.00 37.80  ? 59  GLY B CA  1 
ATOM   3039  C C   . GLY B 1 40  ? 11.048  13.061  125.851 1.00 36.64  ? 59  GLY B C   1 
ATOM   3040  O O   . GLY B 1 40  ? 11.643  13.514  124.875 1.00 36.26  ? 59  GLY B O   1 
ATOM   3041  N N   . LEU B 1 41  ? 9.731   12.930  125.915 1.00 37.13  ? 60  LEU B N   1 
ATOM   3042  C CA  . LEU B 1 41  ? 8.924   13.417  124.823 1.00 36.60  ? 60  LEU B CA  1 
ATOM   3043  C C   . LEU B 1 41  ? 9.029   14.931  124.790 1.00 36.42  ? 60  LEU B C   1 
ATOM   3044  O O   . LEU B 1 41  ? 9.392   15.563  125.781 1.00 36.99  ? 60  LEU B O   1 
ATOM   3045  C CB  . LEU B 1 41  ? 7.468   12.999  124.984 1.00 37.33  ? 60  LEU B CB  1 
ATOM   3046  C CG  . LEU B 1 41  ? 7.138   11.507  124.855 1.00 37.84  ? 60  LEU B CG  1 
ATOM   3047  C CD1 . LEU B 1 41  ? 5.692   11.230  125.166 1.00 38.69  ? 60  LEU B CD1 1 
ATOM   3048  C CD2 . LEU B 1 41  ? 7.528   11.071  123.450 1.00 37.09  ? 60  LEU B CD2 1 
ATOM   3049  N N   . LEU B 1 42  ? 8.701   15.506  123.634 1.00 37.54  ? 61  LEU B N   1 
ATOM   3050  C CA  . LEU B 1 42  ? 8.562   16.947  123.520 1.00 37.68  ? 61  LEU B CA  1 
ATOM   3051  C C   . LEU B 1 42  ? 7.488   17.454  124.479 1.00 38.66  ? 61  LEU B C   1 
ATOM   3052  O O   . LEU B 1 42  ? 6.429   16.838  124.650 1.00 39.12  ? 61  LEU B O   1 
ATOM   3053  C CB  . LEU B 1 42  ? 8.199   17.313  122.095 1.00 37.10  ? 61  LEU B CB  1 
ATOM   3054  C CG  . LEU B 1 42  ? 9.187   16.965  121.001 1.00 36.59  ? 61  LEU B CG  1 
ATOM   3055  C CD1 . LEU B 1 42  ? 8.678   17.530  119.664 1.00 36.23  ? 61  LEU B CD1 1 
ATOM   3056  C CD2 . LEU B 1 42  ? 10.572  17.485  121.263 1.00 37.10  ? 61  LEU B CD2 1 
ATOM   3057  N N   . THR B 1 43  ? 7.768   18.585  125.113 1.00 36.74  ? 62  THR B N   1 
ATOM   3058  C CA  . THR B 1 43  ? 6.749   19.253  125.885 1.00 37.51  ? 62  THR B CA  1 
ATOM   3059  C C   . THR B 1 43  ? 5.579   19.649  124.984 1.00 37.90  ? 62  THR B C   1 
ATOM   3060  O O   . THR B 1 43  ? 5.674   19.651  123.763 1.00 37.37  ? 62  THR B O   1 
ATOM   3061  C CB  . THR B 1 43  ? 7.344   20.490  126.539 1.00 38.25  ? 62  THR B CB  1 
ATOM   3062  O OG1 . THR B 1 43  ? 7.764   21.396  125.498 1.00 38.27  ? 62  THR B OG1 1 
ATOM   3063  C CG2 . THR B 1 43  ? 8.521   20.131  127.370 1.00 38.19  ? 62  THR B CG2 1 
ATOM   3064  N N   . LYS B 1 44  ? 4.453   19.998  125.620 1.00 37.98  ? 63  LYS B N   1 
ATOM   3065  C CA  . LYS B 1 44  ? 3.313   20.562  124.894 1.00 39.33  ? 63  LYS B CA  1 
ATOM   3066  C C   . LYS B 1 44  ? 3.775   21.713  124.011 1.00 38.68  ? 63  LYS B C   1 
ATOM   3067  O O   . LYS B 1 44  ? 3.455   21.760  122.817 1.00 38.38  ? 63  LYS B O   1 
ATOM   3068  C CB  . LYS B 1 44  ? 2.223   21.039  125.864 1.00 42.20  ? 63  LYS B CB  1 
ATOM   3069  N N   . GLU B 1 45  ? 4.569   22.630  124.585 1.00 39.33  ? 64  GLU B N   1 
ATOM   3070  C CA  . GLU B 1 45  ? 5.050   23.805  123.857 1.00 39.71  ? 64  GLU B CA  1 
ATOM   3071  C C   . GLU B 1 45  ? 5.977   23.394  122.713 1.00 37.95  ? 64  GLU B C   1 
ATOM   3072  O O   . GLU B 1 45  ? 5.831   23.895  121.591 1.00 38.03  ? 64  GLU B O   1 
ATOM   3073  C CB  . GLU B 1 45  ? 5.745   24.796  124.816 1.00 41.10  ? 64  GLU B CB  1 
ATOM   3074  N N   . GLU B 1 46  ? 6.946   22.493  122.978 1.00 38.15  ? 65  GLU B N   1 
ATOM   3075  C CA  . GLU B 1 46  ? 7.877   22.054  121.930 1.00 37.26  ? 65  GLU B CA  1 
ATOM   3076  C C   . GLU B 1 46  ? 7.143   21.354  120.785 1.00 36.96  ? 65  GLU B C   1 
ATOM   3077  O O   . GLU B 1 46  ? 7.561   21.439  119.619 1.00 36.32  ? 65  GLU B O   1 
ATOM   3078  C CB  . GLU B 1 46  ? 8.923   21.079  122.489 1.00 36.65  ? 65  GLU B CB  1 
ATOM   3079  C CG  . GLU B 1 46  ? 9.992   21.730  123.322 1.00 37.35  ? 65  GLU B CG  1 
ATOM   3080  C CD  . GLU B 1 46  ? 10.649  20.820  124.352 1.00 37.41  ? 65  GLU B CD  1 
ATOM   3081  O OE1 . GLU B 1 46  ? 10.223  19.663  124.499 1.00 36.91  ? 65  GLU B OE1 1 
ATOM   3082  O OE2 . GLU B 1 46  ? 11.595  21.287  125.023 1.00 38.05  ? 65  GLU B OE2 1 
ATOM   3083  N N   . ALA B 1 47  ? 6.058   20.636  121.112 1.00 38.18  ? 66  ALA B N   1 
ATOM   3084  C CA  . ALA B 1 47  ? 5.296   19.918  120.101 1.00 37.65  ? 66  ALA B CA  1 
ATOM   3085  C C   . ALA B 1 47  ? 4.467   20.880  119.265 1.00 38.27  ? 66  ALA B C   1 
ATOM   3086  O O   . ALA B 1 47  ? 4.397   20.727  118.035 1.00 37.83  ? 66  ALA B O   1 
ATOM   3087  C CB  . ALA B 1 47  ? 4.406   18.854  120.760 1.00 38.18  ? 66  ALA B CB  1 
ATOM   3088  N N   . GLU B 1 48  ? 3.822   21.860  119.925 1.00 36.69  ? 67  GLU B N   1 
ATOM   3089  C CA  . GLU B 1 48  ? 3.084   22.896  119.201 1.00 37.49  ? 67  GLU B CA  1 
ATOM   3090  C C   . GLU B 1 48  ? 4.019   23.629  118.247 1.00 37.25  ? 67  GLU B C   1 
ATOM   3091  O O   . GLU B 1 48  ? 3.671   23.898  117.090 1.00 37.57  ? 67  GLU B O   1 
ATOM   3092  C CB  . GLU B 1 48  ? 2.423   23.876  120.177 1.00 38.71  ? 67  GLU B CB  1 
ATOM   3093  N N   . PHE B 1 49  ? 5.243   23.897  118.702 1.00 36.11  ? 68  PHE B N   1 
ATOM   3094  C CA  . PHE B 1 49  ? 6.191   24.626  117.874 1.00 35.74  ? 68  PHE B CA  1 
ATOM   3095  C C   . PHE B 1 49  ? 6.484   23.861  116.606 1.00 34.94  ? 68  PHE B C   1 
ATOM   3096  O O   . PHE B 1 49  ? 6.547   24.433  115.517 1.00 35.60  ? 68  PHE B O   1 
ATOM   3097  C CB  . PHE B 1 49  ? 7.465   24.862  118.664 1.00 35.98  ? 68  PHE B CB  1 
ATOM   3098  C CG  . PHE B 1 49  ? 8.565   25.494  117.875 1.00 35.95  ? 68  PHE B CG  1 
ATOM   3099  C CD1 . PHE B 1 49  ? 9.416   24.734  117.103 1.00 35.06  ? 68  PHE B CD1 1 
ATOM   3100  C CD2 . PHE B 1 49  ? 8.752   26.865  117.911 1.00 37.13  ? 68  PHE B CD2 1 
ATOM   3101  C CE1 . PHE B 1 49  ? 10.438  25.335  116.390 1.00 35.53  ? 68  PHE B CE1 1 
ATOM   3102  C CE2 . PHE B 1 49  ? 9.765   27.465  117.209 1.00 37.68  ? 68  PHE B CE2 1 
ATOM   3103  C CZ  . PHE B 1 49  ? 10.620  26.724  116.470 1.00 36.36  ? 68  PHE B CZ  1 
ATOM   3104  N N   . VAL B 1 50  ? 6.695   22.553  116.739 1.00 36.94  ? 69  VAL B N   1 
ATOM   3105  C CA  . VAL B 1 50  ? 7.063   21.726  115.599 1.00 36.44  ? 69  VAL B CA  1 
ATOM   3106  C C   . VAL B 1 50  ? 5.856   21.499  114.715 1.00 36.54  ? 69  VAL B C   1 
ATOM   3107  O O   . VAL B 1 50  ? 5.897   21.750  113.504 1.00 36.59  ? 69  VAL B O   1 
ATOM   3108  C CB  . VAL B 1 50  ? 7.668   20.408  116.105 1.00 36.58  ? 69  VAL B CB  1 
ATOM   3109  C CG1 . VAL B 1 50  ? 7.582   19.332  115.076 1.00 36.76  ? 69  VAL B CG1 1 
ATOM   3110  C CG2 . VAL B 1 50  ? 9.125   20.645  116.475 1.00 36.49  ? 69  VAL B CG2 1 
ATOM   3111  N N   . ALA B 1 51  ? 4.745   21.086  115.326 1.00 36.56  ? 70  ALA B N   1 
ATOM   3112  C CA  . ALA B 1 51  ? 3.559   20.675  114.578 1.00 36.70  ? 70  ALA B CA  1 
ATOM   3113  C C   . ALA B 1 51  ? 2.963   21.812  113.769 1.00 37.58  ? 70  ALA B C   1 
ATOM   3114  O O   . ALA B 1 51  ? 2.264   21.560  112.783 1.00 38.03  ? 70  ALA B O   1 
ATOM   3115  C CB  . ALA B 1 51  ? 2.506   20.124  115.546 1.00 37.72  ? 70  ALA B CB  1 
ATOM   3116  N N   . THR B 1 52  ? 3.254   23.044  114.154 1.00 36.09  ? 71  THR B N   1 
ATOM   3117  C CA  . THR B 1 52  ? 2.729   24.240  113.540 1.00 37.42  ? 71  THR B CA  1 
ATOM   3118  C C   . THR B 1 52  ? 3.618   24.831  112.477 1.00 37.31  ? 71  THR B C   1 
ATOM   3119  O O   . THR B 1 52  ? 3.181   25.722  111.750 1.00 39.04  ? 71  THR B O   1 
ATOM   3120  C CB  . THR B 1 52  ? 2.536   25.298  114.591 1.00 38.83  ? 71  THR B CB  1 
ATOM   3121  O OG1 . THR B 1 52  ? 1.605   24.781  115.529 1.00 39.48  ? 71  THR B OG1 1 
ATOM   3122  C CG2 . THR B 1 52  ? 1.960   26.538  113.979 1.00 40.48  ? 71  THR B CG2 1 
ATOM   3123  N N   . ARG B 1 53  ? 4.845   24.382  112.359 1.00 38.01  ? 72  ARG B N   1 
ATOM   3124  C CA  . ARG B 1 53  ? 5.791   25.021  111.465 1.00 38.18  ? 72  ARG B CA  1 
ATOM   3125  C C   . ARG B 1 53  ? 6.219   24.104  110.340 1.00 37.32  ? 72  ARG B C   1 
ATOM   3126  O O   . ARG B 1 53  ? 6.983   24.519  109.460 1.00 37.70  ? 72  ARG B O   1 
ATOM   3127  C CB  . ARG B 1 53  ? 6.999   25.490  112.277 1.00 38.41  ? 72  ARG B CB  1 
ATOM   3128  C CG  . ARG B 1 53  ? 6.891   26.936  112.645 1.00 39.55  ? 72  ARG B CG  1 
ATOM   3129  C CD  . ARG B 1 53  ? 7.779   27.334  113.786 1.00 39.97  ? 72  ARG B CD  1 
ATOM   3130  N NE  . ARG B 1 53  ? 6.969   27.313  114.982 1.00 40.62  ? 72  ARG B NE  1 
ATOM   3131  C CZ  . ARG B 1 53  ? 6.902   28.303  115.841 1.00 41.78  ? 72  ARG B CZ  1 
ATOM   3132  N NH1 . ARG B 1 53  ? 7.754   29.317  115.791 1.00 42.73  ? 72  ARG B NH1 1 
ATOM   3133  N NH2 . ARG B 1 53  ? 5.945   28.289  116.764 1.00 42.77  ? 72  ARG B NH2 1 
ATOM   3134  N N   . SER B 1 54  ? 5.718   22.877  110.325 1.00 38.22  ? 73  SER B N   1 
ATOM   3135  C CA  . SER B 1 54  ? 6.208   21.877  109.393 1.00 37.57  ? 73  SER B CA  1 
ATOM   3136  C C   . SER B 1 54  ? 5.196   20.746  109.314 1.00 37.38  ? 73  SER B C   1 
ATOM   3137  O O   . SER B 1 54  ? 4.321   20.610  110.171 1.00 38.03  ? 73  SER B O   1 
ATOM   3138  C CB  . SER B 1 54  ? 7.590   21.362  109.818 1.00 36.59  ? 73  SER B CB  1 
ATOM   3139  O OG  . SER B 1 54  ? 8.049   20.288  109.000 1.00 35.88  ? 73  SER B OG  1 
ATOM   3140  N N   . ASN B 1 55  ? 5.314   19.971  108.231 1.00 36.90  ? 74  ASN B N   1 
ATOM   3141  C CA  . ASN B 1 55  ? 4.574   18.732  108.020 1.00 36.44  ? 74  ASN B CA  1 
ATOM   3142  C C   . ASN B 1 55  ? 5.494   17.526  107.876 1.00 35.25  ? 74  ASN B C   1 
ATOM   3143  O O   . ASN B 1 55  ? 5.047   16.471  107.424 1.00 35.37  ? 74  ASN B O   1 
ATOM   3144  C CB  . ASN B 1 55  ? 3.699   18.828  106.761 1.00 37.42  ? 74  ASN B CB  1 
ATOM   3145  C CG  . ASN B 1 55  ? 2.535   19.730  106.954 1.00 38.65  ? 74  ASN B CG  1 
ATOM   3146  O OD1 . ASN B 1 55  ? 2.081   19.940  108.072 1.00 39.56  ? 74  ASN B OD1 1 
ATOM   3147  N ND2 . ASN B 1 55  ? 2.007   20.245  105.853 1.00 39.95  ? 74  ASN B ND2 1 
ATOM   3148  N N   . PHE B 1 56  ? 6.756   17.647  108.218 1.00 35.54  ? 75  PHE B N   1 
ATOM   3149  C CA  . PHE B 1 56  ? 7.724   16.634  107.823 1.00 34.01  ? 75  PHE B CA  1 
ATOM   3150  C C   . PHE B 1 56  ? 8.840   16.610  108.849 1.00 33.51  ? 75  PHE B C   1 
ATOM   3151  O O   . PHE B 1 56  ? 9.648   17.536  108.904 1.00 34.04  ? 75  PHE B O   1 
ATOM   3152  C CB  . PHE B 1 56  ? 8.247   16.966  106.435 1.00 34.42  ? 75  PHE B CB  1 
ATOM   3153  C CG  . PHE B 1 56  ? 8.958   15.858  105.753 1.00 33.46  ? 75  PHE B CG  1 
ATOM   3154  C CD1 . PHE B 1 56  ? 8.772   14.545  106.118 1.00 33.04  ? 75  PHE B CD1 1 
ATOM   3155  C CD2 . PHE B 1 56  ? 9.813   16.143  104.711 1.00 33.50  ? 75  PHE B CD2 1 
ATOM   3156  C CE1 . PHE B 1 56  ? 9.439   13.527  105.454 1.00 32.52  ? 75  PHE B CE1 1 
ATOM   3157  C CE2 . PHE B 1 56  ? 10.470  15.145  104.047 1.00 33.03  ? 75  PHE B CE2 1 
ATOM   3158  C CZ  . PHE B 1 56  ? 10.286  13.835  104.420 1.00 32.58  ? 75  PHE B CZ  1 
ATOM   3159  N N   . ILE B 1 57  ? 8.903   15.552  109.647 1.00 33.53  ? 76  ILE B N   1 
ATOM   3160  C CA  . ILE B 1 57  ? 9.888   15.446  110.718 1.00 33.23  ? 76  ILE B CA  1 
ATOM   3161  C C   . ILE B 1 57  ? 10.393  14.015  110.833 1.00 32.79  ? 76  ILE B C   1 
ATOM   3162  O O   . ILE B 1 57  ? 9.611   13.059  110.880 1.00 32.93  ? 76  ILE B O   1 
ATOM   3163  C CB  . ILE B 1 57  ? 9.304   15.909  112.061 1.00 33.89  ? 76  ILE B CB  1 
ATOM   3164  C CG1 . ILE B 1 57  ? 10.339  15.781  113.167 1.00 34.17  ? 76  ILE B CG1 1 
ATOM   3165  C CG2 . ILE B 1 57  ? 8.133   15.069  112.438 1.00 34.14  ? 76  ILE B CG2 1 
ATOM   3166  C CD1 . ILE B 1 57  ? 10.011  16.600  114.401 1.00 35.17  ? 76  ILE B CD1 1 
ATOM   3167  N N   . CYS B 1 58  ? 11.712  13.874  110.878 1.00 33.21  ? 77  CYS B N   1 
ATOM   3168  C CA  . CYS B 1 58  ? 12.356  12.616  111.223 1.00 33.08  ? 77  CYS B CA  1 
ATOM   3169  C C   . CYS B 1 58  ? 12.773  12.661  112.695 1.00 34.13  ? 77  CYS B C   1 
ATOM   3170  O O   . CYS B 1 58  ? 13.543  13.528  113.106 1.00 34.40  ? 77  CYS B O   1 
ATOM   3171  C CB  . CYS B 1 58  ? 13.569  12.334  110.345 1.00 33.03  ? 77  CYS B CB  1 
ATOM   3172  S SG  . CYS B 1 58  ? 14.365  10.803  110.976 1.00 33.74  ? 77  CYS B SG  1 
ATOM   3173  N N   . LEU B 1 59  ? 12.289  11.715  113.476 1.00 32.11  ? 78  LEU B N   1 
ATOM   3174  C CA  . LEU B 1 59  ? 12.711  11.621  114.866 1.00 32.87  ? 78  LEU B CA  1 
ATOM   3175  C C   . LEU B 1 59  ? 13.932  10.725  114.960 1.00 33.58  ? 78  LEU B C   1 
ATOM   3176  O O   . LEU B 1 59  ? 13.899  9.599   114.482 1.00 33.89  ? 78  LEU B O   1 
ATOM   3177  C CB  . LEU B 1 59  ? 11.576  11.079  115.727 1.00 33.23  ? 78  LEU B CB  1 
ATOM   3178  C CG  . LEU B 1 59  ? 10.421  12.069  115.852 1.00 33.13  ? 78  LEU B CG  1 
ATOM   3179  C CD1 . LEU B 1 59  ? 9.190   11.362  116.431 1.00 33.33  ? 78  LEU B CD1 1 
ATOM   3180  C CD2 . LEU B 1 59  ? 10.823  13.251  116.715 1.00 33.73  ? 78  LEU B CD2 1 
ATOM   3181  N N   . GLU B 1 60  ? 14.987  11.210  115.604 1.00 32.96  ? 79  GLU B N   1 
ATOM   3182  C CA  . GLU B 1 60  ? 16.249  10.487  115.595 1.00 33.95  ? 79  GLU B CA  1 
ATOM   3183  C C   . GLU B 1 60  ? 16.309  9.341   116.625 1.00 35.30  ? 79  GLU B C   1 
ATOM   3184  O O   . GLU B 1 60  ? 15.475  9.220   117.539 1.00 35.60  ? 79  GLU B O   1 
ATOM   3185  C CB  . GLU B 1 60  ? 17.398  11.426  115.883 1.00 34.11  ? 79  GLU B CB  1 
ATOM   3186  C CG  . GLU B 1 60  ? 18.119  11.887  114.674 1.00 34.29  ? 79  GLU B CG  1 
ATOM   3187  C CD  . GLU B 1 60  ? 19.166  10.929  114.185 1.00 34.88  ? 79  GLU B CD  1 
ATOM   3188  O OE1 . GLU B 1 60  ? 19.520  9.986   114.916 1.00 35.61  ? 79  GLU B OE1 1 
ATOM   3189  O OE2 . GLU B 1 60  ? 19.635  11.121  113.046 1.00 34.92  ? 79  GLU B OE2 1 
ATOM   3190  N N   . LYS B 1 61  ? 17.337  8.488   116.438 1.00 35.03  ? 80  LYS B N   1 
ATOM   3191  C CA  . LYS B 1 61  ? 17.722  7.511   117.459 1.00 36.25  ? 80  LYS B CA  1 
ATOM   3192  C C   . LYS B 1 61  ? 17.782  8.166   118.843 1.00 36.26  ? 80  LYS B C   1 
ATOM   3193  O O   . LYS B 1 61  ? 18.119  9.337   118.989 1.00 35.52  ? 80  LYS B O   1 
ATOM   3194  C CB  . LYS B 1 61  ? 19.096  6.883   117.102 1.00 36.90  ? 80  LYS B CB  1 
ATOM   3195  C CG  . LYS B 1 61  ? 20.287  7.816   117.254 1.00 36.43  ? 80  LYS B CG  1 
ATOM   3196  C CD  . LYS B 1 61  ? 21.649  7.181   116.949 1.00 36.10  ? 80  LYS B CD  1 
ATOM   3197  C CE  . LYS B 1 61  ? 22.057  7.357   115.506 1.00 35.90  ? 80  LYS B CE  1 
ATOM   3198  N NZ  . LYS B 1 61  ? 22.014  8.788   114.998 1.00 35.73  ? 80  LYS B NZ  1 
ATOM   3199  N N   . GLY B 1 62  ? 17.401  7.390   119.850 1.00 36.65  ? 81  GLY B N   1 
ATOM   3200  C CA  . GLY B 1 62  ? 17.475  7.825   121.215 1.00 36.56  ? 81  GLY B CA  1 
ATOM   3201  C C   . GLY B 1 62  ? 16.254  8.524   121.738 1.00 36.11  ? 81  GLY B C   1 
ATOM   3202  O O   . GLY B 1 62  ? 16.201  8.811   122.949 1.00 36.64  ? 81  GLY B O   1 
ATOM   3203  N N   . HIS B 1 63  ? 15.262  8.781   120.884 1.00 36.71  ? 82  HIS B N   1 
ATOM   3204  C CA  . HIS B 1 63  ? 14.242  9.773   121.211 1.00 35.82  ? 82  HIS B CA  1 
ATOM   3205  C C   . HIS B 1 63  ? 13.332  9.284   122.338 1.00 36.58  ? 82  HIS B C   1 
ATOM   3206  O O   . HIS B 1 63  ? 12.639  8.271   122.194 1.00 37.09  ? 82  HIS B O   1 
ATOM   3207  C CB  . HIS B 1 63  ? 13.387  10.145  120.006 1.00 34.77  ? 82  HIS B CB  1 
ATOM   3208  C CG  . HIS B 1 63  ? 12.341  11.156  120.340 1.00 34.13  ? 82  HIS B CG  1 
ATOM   3209  N ND1 . HIS B 1 63  ? 12.642  12.483  120.542 1.00 34.07  ? 82  HIS B ND1 1 
ATOM   3210  C CD2 . HIS B 1 63  ? 11.022  11.025  120.619 1.00 34.18  ? 82  HIS B CD2 1 
ATOM   3211  C CE1 . HIS B 1 63  ? 11.546  13.132  120.892 1.00 34.10  ? 82  HIS B CE1 1 
ATOM   3212  N NE2 . HIS B 1 63  ? 10.545  12.273  120.937 1.00 34.02  ? 82  HIS B NE2 1 
ATOM   3213  N N   . ALA B 1 64  ? 13.321  10.031  123.441 1.00 35.97  ? 83  ALA B N   1 
ATOM   3214  C CA  . ALA B 1 64  ? 12.484  9.769   124.606 1.00 36.45  ? 83  ALA B CA  1 
ATOM   3215  C C   . ALA B 1 64  ? 12.845  8.459   125.297 1.00 37.94  ? 83  ALA B C   1 
ATOM   3216  O O   . ALA B 1 64  ? 12.042  7.914   126.065 1.00 38.97  ? 83  ALA B O   1 
ATOM   3217  C CB  . ALA B 1 64  ? 11.008  9.782   124.224 1.00 36.47  ? 83  ALA B CB  1 
ATOM   3218  N N   . THR B 1 65  ? 14.051  7.941   125.052 1.00 37.59  ? 84  THR B N   1 
ATOM   3219  C CA  . THR B 1 65  ? 14.426  6.670   125.661 1.00 38.70  ? 84  THR B CA  1 
ATOM   3220  C C   . THR B 1 65  ? 14.542  6.787   127.166 1.00 39.64  ? 84  THR B C   1 
ATOM   3221  O O   . THR B 1 65  ? 14.238  5.830   127.880 1.00 40.96  ? 84  THR B O   1 
ATOM   3222  C CB  . THR B 1 65  ? 15.726  6.162   125.057 1.00 39.25  ? 84  THR B CB  1 
ATOM   3223  O OG1 . THR B 1 65  ? 16.688  7.203   125.082 1.00 38.52  ? 84  THR B OG1 1 
ATOM   3224  C CG2 . THR B 1 65  ? 15.488  5.708   123.583 1.00 38.98  ? 84  THR B CG2 1 
ATOM   3225  N N   . ARG B 1 66  ? 14.922  7.952   127.671 1.00 42.58  ? 85  ARG B N   1 
ATOM   3226  C CA  . ARG B 1 66  ? 15.057  8.107   129.108 1.00 43.50  ? 85  ARG B CA  1 
ATOM   3227  C C   . ARG B 1 66  ? 13.748  7.864   129.833 1.00 44.18  ? 85  ARG B C   1 
ATOM   3228  O O   . ARG B 1 66  ? 13.750  7.426   130.982 1.00 45.86  ? 85  ARG B O   1 
ATOM   3229  C CB  . ARG B 1 66  ? 15.585  9.504   129.435 1.00 43.34  ? 85  ARG B CB  1 
ATOM   3230  C CG  . ARG B 1 66  ? 15.142  10.032  130.813 1.00 44.67  ? 85  ARG B CG  1 
ATOM   3231  C CD  . ARG B 1 66  ? 15.971  11.273  131.245 1.00 44.61  ? 85  ARG B CD  1 
ATOM   3232  N NE  . ARG B 1 66  ? 17.306  11.179  130.650 1.00 44.85  ? 85  ARG B NE  1 
ATOM   3233  C CZ  . ARG B 1 66  ? 18.196  12.158  130.616 1.00 45.37  ? 85  ARG B CZ  1 
ATOM   3234  N NH1 . ARG B 1 66  ? 17.966  13.304  131.217 1.00 46.06  ? 85  ARG B NH1 1 
ATOM   3235  N NH2 . ARG B 1 66  ? 19.328  11.989  129.936 1.00 44.97  ? 85  ARG B NH2 1 
ATOM   3236  N N   . THR B 1 67  ? 12.624  8.129   129.192 1.00 38.88  ? 86  THR B N   1 
ATOM   3237  C CA  . THR B 1 67  ? 11.321  7.862   129.797 1.00 39.45  ? 86  THR B CA  1 
ATOM   3238  C C   . THR B 1 67  ? 10.600  6.666   129.192 1.00 40.03  ? 86  THR B C   1 
ATOM   3239  O O   . THR B 1 67  ? 9.609   6.214   129.763 1.00 41.26  ? 86  THR B O   1 
ATOM   3240  C CB  . THR B 1 67  ? 10.380  9.078   129.643 1.00 38.91  ? 86  THR B CB  1 
ATOM   3241  O OG1 . THR B 1 67  ? 10.277  9.404   128.250 1.00 37.94  ? 86  THR B OG1 1 
ATOM   3242  C CG2 . THR B 1 67  ? 10.900  10.291  130.454 1.00 39.05  ? 86  THR B CG2 1 
ATOM   3243  N N   . HIS B 1 68  ? 11.041  6.194   128.033 1.00 39.54  ? 87  HIS B N   1 
ATOM   3244  C CA  . HIS B 1 68  ? 10.327  5.164   127.296 1.00 39.74  ? 87  HIS B CA  1 
ATOM   3245  C C   . HIS B 1 68  ? 11.158  3.925   126.993 1.00 40.84  ? 87  HIS B C   1 
ATOM   3246  O O   . HIS B 1 68  ? 10.591  2.930   126.532 1.00 41.27  ? 87  HIS B O   1 
ATOM   3247  C CB  . HIS B 1 68  ? 9.768   5.729   125.978 1.00 38.44  ? 87  HIS B CB  1 
ATOM   3248  C CG  . HIS B 1 68  ? 8.600   6.637   126.183 1.00 37.96  ? 87  HIS B CG  1 
ATOM   3249  N ND1 . HIS B 1 68  ? 8.695   7.801   126.906 1.00 38.09  ? 87  HIS B ND1 1 
ATOM   3250  C CD2 . HIS B 1 68  ? 7.308   6.538   125.800 1.00 38.02  ? 87  HIS B CD2 1 
ATOM   3251  C CE1 . HIS B 1 68  ? 7.516   8.397   126.939 1.00 38.01  ? 87  HIS B CE1 1 
ATOM   3252  N NE2 . HIS B 1 68  ? 6.655   7.645   126.284 1.00 38.14  ? 87  HIS B NE2 1 
ATOM   3253  N N   . GLY B 1 69  ? 12.462  3.946   127.258 1.00 37.04  ? 88  GLY B N   1 
ATOM   3254  C CA  . GLY B 1 69  ? 13.297  2.762   127.221 1.00 38.07  ? 88  GLY B CA  1 
ATOM   3255  C C   . GLY B 1 69  ? 13.959  2.556   125.887 1.00 38.01  ? 88  GLY B C   1 
ATOM   3256  O O   . GLY B 1 69  ? 15.190  2.500   125.752 1.00 39.22  ? 88  GLY B O   1 
ATOM   3257  N N   . THR B 1 70  ? 13.117  2.461   124.882 1.00 38.64  ? 89  THR B N   1 
ATOM   3258  C CA  . THR B 1 70  ? 13.549  2.123   123.547 1.00 38.03  ? 89  THR B CA  1 
ATOM   3259  C C   . THR B 1 70  ? 13.170  3.238   122.605 1.00 36.37  ? 89  THR B C   1 
ATOM   3260  O O   . THR B 1 70  ? 12.135  3.862   122.760 1.00 35.60  ? 89  THR B O   1 
ATOM   3261  C CB  . THR B 1 70  ? 12.890  0.827   123.071 1.00 39.01  ? 89  THR B CB  1 
ATOM   3262  O OG1 . THR B 1 70  ? 11.464  1.018   123.029 1.00 38.08  ? 89  THR B OG1 1 
ATOM   3263  C CG2 . THR B 1 70  ? 13.197  -0.274  124.014 1.00 40.67  ? 89  THR B CG2 1 
ATOM   3264  N N   . THR B 1 71  ? 14.005  3.452   121.605 1.00 37.44  ? 90  THR B N   1 
ATOM   3265  C CA  . THR B 1 71  ? 13.683  4.446   120.595 1.00 35.90  ? 90  THR B CA  1 
ATOM   3266  C C   . THR B 1 71  ? 12.327  4.151   119.956 1.00 34.98  ? 90  THR B C   1 
ATOM   3267  O O   . THR B 1 71  ? 11.551  5.072   119.682 1.00 33.89  ? 90  THR B O   1 
ATOM   3268  C CB  . THR B 1 71  ? 14.791  4.491   119.553 1.00 36.08  ? 90  THR B CB  1 
ATOM   3269  O OG1 . THR B 1 71  ? 16.012  4.929   120.152 1.00 36.76  ? 90  THR B OG1 1 
ATOM   3270  C CG2 . THR B 1 71  ? 14.418  5.455   118.457 1.00 34.65  ? 90  THR B CG2 1 
ATOM   3271  N N   . GLU B 1 72  ? 12.013  2.874   119.729 1.00 37.12  ? 91  GLU B N   1 
ATOM   3272  C CA  . GLU B 1 72  ? 10.715  2.539   119.160 1.00 35.91  ? 91  GLU B CA  1 
ATOM   3273  C C   . GLU B 1 72  ? 9.592   3.068   120.036 1.00 36.02  ? 91  GLU B C   1 
ATOM   3274  O O   . GLU B 1 72  ? 8.661   3.729   119.564 1.00 35.07  ? 91  GLU B O   1 
ATOM   3275  C CB  . GLU B 1 72  ? 10.565  1.025   118.989 1.00 36.72  ? 91  GLU B CB  1 
ATOM   3276  C CG  . GLU B 1 72  ? 11.532  0.405   118.010 1.00 37.00  ? 91  GLU B CG  1 
ATOM   3277  C CD  . GLU B 1 72  ? 12.694  -0.314  118.712 1.00 38.40  ? 91  GLU B CD  1 
ATOM   3278  O OE1 . GLU B 1 72  ? 13.162  0.194   119.778 1.00 39.10  ? 91  GLU B OE1 1 
ATOM   3279  O OE2 . GLU B 1 72  ? 13.146  -1.358  118.177 1.00 39.27  ? 91  GLU B OE2 1 
ATOM   3280  N N   . ALA B 1 73  ? 9.617   2.734   121.309 1.00 37.19  ? 92  ALA B N   1 
ATOM   3281  C CA  . ALA B 1 73  ? 8.520   3.173   122.159 1.00 37.24  ? 92  ALA B CA  1 
ATOM   3282  C C   . ALA B 1 73  ? 8.426   4.699   122.175 1.00 36.37  ? 92  ALA B C   1 
ATOM   3283  O O   . ALA B 1 73  ? 7.325   5.273   122.150 1.00 36.08  ? 92  ALA B O   1 
ATOM   3284  C CB  . ALA B 1 73  ? 8.733   2.616   123.556 1.00 39.11  ? 92  ALA B CB  1 
ATOM   3285  N N   . GLY B 1 74  ? 9.574   5.379   122.206 1.00 36.27  ? 93  GLY B N   1 
ATOM   3286  C CA  . GLY B 1 74  ? 9.553   6.812   122.394 1.00 35.85  ? 93  GLY B CA  1 
ATOM   3287  C C   . GLY B 1 74  ? 9.090   7.520   121.152 1.00 34.38  ? 93  GLY B C   1 
ATOM   3288  O O   . GLY B 1 74  ? 8.317   8.474   121.235 1.00 34.20  ? 93  GLY B O   1 
ATOM   3289  N N   . ILE B 1 75  ? 9.541   7.049   119.989 1.00 36.03  ? 94  ILE B N   1 
ATOM   3290  C CA  . ILE B 1 75  ? 9.075   7.598   118.722 1.00 34.71  ? 94  ILE B CA  1 
ATOM   3291  C C   . ILE B 1 75  ? 7.591   7.334   118.530 1.00 34.58  ? 94  ILE B C   1 
ATOM   3292  O O   . ILE B 1 75  ? 6.842   8.196   118.056 1.00 34.18  ? 94  ILE B O   1 
ATOM   3293  C CB  . ILE B 1 75  ? 9.899   7.036   117.550 1.00 33.99  ? 94  ILE B CB  1 
ATOM   3294  C CG1 . ILE B 1 75  ? 11.298  7.630   117.637 1.00 34.43  ? 94  ILE B CG1 1 
ATOM   3295  C CG2 . ILE B 1 75  ? 9.180   7.336   116.241 1.00 32.99  ? 94  ILE B CG2 1 
ATOM   3296  C CD1 . ILE B 1 75  ? 12.229  7.203   116.548 1.00 34.29  ? 94  ILE B CD1 1 
ATOM   3297  N N   . GLU B 1 76  ? 7.137   6.151   118.892 1.00 36.78  ? 95  GLU B N   1 
ATOM   3298  C CA  . GLU B 1 76  ? 5.712   5.875   118.748 1.00 36.94  ? 95  GLU B CA  1 
ATOM   3299  C C   . GLU B 1 76  ? 4.888   6.914   119.507 1.00 37.29  ? 95  GLU B C   1 
ATOM   3300  O O   . GLU B 1 76  ? 3.924   7.472   118.976 1.00 37.44  ? 95  GLU B O   1 
ATOM   3301  C CB  . GLU B 1 76  ? 5.381   4.448   119.213 1.00 38.18  ? 95  GLU B CB  1 
ATOM   3302  C CG  . GLU B 1 76  ? 3.881   4.155   119.196 1.00 38.32  ? 95  GLU B CG  1 
ATOM   3303  C CD  . GLU B 1 76  ? 3.248   4.317   117.804 1.00 38.12  ? 95  GLU B CD  1 
ATOM   3304  O OE1 . GLU B 1 76  ? 3.977   4.274   116.780 1.00 37.52  ? 95  GLU B OE1 1 
ATOM   3305  O OE2 . GLU B 1 76  ? 2.009   4.477   117.736 1.00 39.07  ? 95  GLU B OE2 1 
ATOM   3306  N N   . ALA B 1 77  ? 5.249   7.176   120.758 1.00 35.97  ? 96  ALA B N   1 
ATOM   3307  C CA  . ALA B 1 77  ? 4.474   8.129   121.545 1.00 36.59  ? 96  ALA B CA  1 
ATOM   3308  C C   . ALA B 1 77  ? 4.561   9.529   120.946 1.00 36.19  ? 96  ALA B C   1 
ATOM   3309  O O   . ALA B 1 77  ? 3.584   10.283  120.966 1.00 36.46  ? 96  ALA B O   1 
ATOM   3310  C CB  . ALA B 1 77  ? 4.968   8.121   122.990 1.00 38.00  ? 96  ALA B CB  1 
ATOM   3311  N N   . GLU B 1 78  ? 5.732   9.888   120.418 1.00 37.12  ? 97  GLU B N   1 
ATOM   3312  C CA  . GLU B 1 78  ? 5.943   11.225  119.893 1.00 36.56  ? 97  GLU B CA  1 
ATOM   3313  C C   . GLU B 1 78  ? 5.146   11.430  118.609 1.00 35.80  ? 97  GLU B C   1 
ATOM   3314  O O   . GLU B 1 78  ? 4.551   12.496  118.397 1.00 36.33  ? 97  GLU B O   1 
ATOM   3315  C CB  . GLU B 1 78  ? 7.431   11.437  119.668 1.00 36.25  ? 97  GLU B CB  1 
ATOM   3316  C CG  . GLU B 1 78  ? 7.768   12.830  119.211 1.00 35.75  ? 97  GLU B CG  1 
ATOM   3317  C CD  . GLU B 1 78  ? 7.406   13.916  120.256 1.00 36.80  ? 97  GLU B CD  1 
ATOM   3318  O OE1 . GLU B 1 78  ? 8.020   13.961  121.364 1.00 37.28  ? 97  GLU B OE1 1 
ATOM   3319  O OE2 . GLU B 1 78  ? 6.494   14.730  119.970 1.00 37.35  ? 97  GLU B OE2 1 
ATOM   3320  N N   . ALA B 1 79  ? 5.096   10.412  117.756 1.00 36.31  ? 98  ALA B N   1 
ATOM   3321  C CA  . ALA B 1 79  ? 4.273   10.495  116.558 1.00 36.01  ? 98  ALA B CA  1 
ATOM   3322  C C   . ALA B 1 79  ? 2.817   10.710  116.920 1.00 36.82  ? 98  ALA B C   1 
ATOM   3323  O O   . ALA B 1 79  ? 2.103   11.466  116.263 1.00 37.52  ? 98  ALA B O   1 
ATOM   3324  C CB  . ALA B 1 79  ? 4.438   9.223   115.732 1.00 36.01  ? 98  ALA B CB  1 
ATOM   3325  N N   . ARG B 1 80  ? 2.368   10.085  117.989 1.00 38.07  ? 99  ARG B N   1 
ATOM   3326  C CA  . ARG B 1 80  ? 0.982   10.261  118.368 1.00 39.56  ? 99  ARG B CA  1 
ATOM   3327  C C   . ARG B 1 80  ? 0.700   11.687  118.799 1.00 40.05  ? 99  ARG B C   1 
ATOM   3328  O O   . ARG B 1 80  ? -0.333  12.239  118.419 1.00 41.04  ? 99  ARG B O   1 
ATOM   3329  C CB  . ARG B 1 80  ? 0.598   9.306   119.479 1.00 40.98  ? 99  ARG B CB  1 
ATOM   3330  C CG  . ARG B 1 80  ? 0.128   8.002   118.959 1.00 41.86  ? 99  ARG B CG  1 
ATOM   3331  C CD  . ARG B 1 80  ? 0.608   6.888   119.858 1.00 43.11  ? 99  ARG B CD  1 
ATOM   3332  N NE  . ARG B 1 80  ? 0.203   5.578   119.362 1.00 44.35  ? 99  ARG B NE  1 
ATOM   3333  C CZ  . ARG B 1 80  ? -0.387  4.643   120.093 1.00 47.14  ? 99  ARG B CZ  1 
ATOM   3334  N NH1 . ARG B 1 80  ? -0.592  4.805   121.388 1.00 48.82  ? 99  ARG B NH1 1 
ATOM   3335  N NH2 . ARG B 1 80  ? -0.797  3.526   119.502 1.00 48.24  ? 99  ARG B NH2 1 
ATOM   3336  N N   . GLN B 1 81  ? 1.580   12.306  119.600 1.00 40.24  ? 100 GLN B N   1 
ATOM   3337  C CA  . GLN B 1 81  ? 1.251   13.650  120.045 1.00 41.03  ? 100 GLN B CA  1 
ATOM   3338  C C   . GLN B 1 81  ? 1.408   14.643  118.898 1.00 40.50  ? 100 GLN B C   1 
ATOM   3339  O O   . GLN B 1 81  ? 0.585   15.544  118.739 1.00 41.43  ? 100 GLN B O   1 
ATOM   3340  C CB  . GLN B 1 81  ? 2.071   14.066  121.277 1.00 42.28  ? 100 GLN B CB  1 
ATOM   3341  C CG  . GLN B 1 81  ? 3.559   14.428  121.150 1.00 42.06  ? 100 GLN B CG  1 
ATOM   3342  C CD  . GLN B 1 81  ? 4.103   15.109  122.445 1.00 42.89  ? 100 GLN B CD  1 
ATOM   3343  O OE1 . GLN B 1 81  ? 3.364   15.342  123.421 1.00 44.64  ? 100 GLN B OE1 1 
ATOM   3344  N NE2 . GLN B 1 81  ? 5.393   15.411  122.452 1.00 41.83  ? 100 GLN B NE2 1 
ATOM   3345  N N   . LEU B 1 82  ? 2.410   14.451  118.050 1.00 39.66  ? 101 LEU B N   1 
ATOM   3346  C CA  . LEU B 1 82  ? 2.581   15.370  116.936 1.00 39.37  ? 101 LEU B CA  1 
ATOM   3347  C C   . LEU B 1 82  ? 1.399   15.329  115.978 1.00 39.89  ? 101 LEU B C   1 
ATOM   3348  O O   . LEU B 1 82  ? 0.943   16.377  115.506 1.00 40.51  ? 101 LEU B O   1 
ATOM   3349  C CB  . LEU B 1 82  ? 3.852   15.044  116.181 1.00 38.22  ? 101 LEU B CB  1 
ATOM   3350  C CG  . LEU B 1 82  ? 5.119   15.375  116.934 1.00 37.98  ? 101 LEU B CG  1 
ATOM   3351  C CD1 . LEU B 1 82  ? 6.292   14.863  116.170 1.00 37.41  ? 101 LEU B CD1 1 
ATOM   3352  C CD2 . LEU B 1 82  ? 5.209   16.846  117.103 1.00 39.09  ? 101 LEU B CD2 1 
ATOM   3353  N N   . LYS B 1 83  ? 0.901   14.142  115.656 1.00 39.70  ? 102 LYS B N   1 
ATOM   3354  C CA  . LYS B 1 83  ? -0.190  14.055  114.711 1.00 40.71  ? 102 LYS B CA  1 
ATOM   3355  C C   . LYS B 1 83  ? -1.541  14.357  115.331 1.00 42.22  ? 102 LYS B C   1 
ATOM   3356  O O   . LYS B 1 83  ? -2.508  14.592  114.583 1.00 43.43  ? 102 LYS B O   1 
ATOM   3357  C CB  . LYS B 1 83  ? -0.222  12.672  114.103 1.00 41.16  ? 102 LYS B CB  1 
ATOM   3358  C CG  . LYS B 1 83  ? 0.800   12.451  113.034 1.00 40.68  ? 102 LYS B CG  1 
ATOM   3359  C CD  . LYS B 1 83  ? 0.935   10.951  112.843 1.00 41.44  ? 102 LYS B CD  1 
ATOM   3360  C CE  . LYS B 1 83  ? 1.203   10.544  111.404 1.00 41.15  ? 102 LYS B CE  1 
ATOM   3361  N NZ  . LYS B 1 83  ? 0.333   9.366   111.116 1.00 41.39  ? 102 LYS B NZ  1 
ATOM   3362  N N   . ASN B 1 84  ? -1.647  14.330  116.661 1.00 45.25  ? 103 ASN B N   1 
ATOM   3363  C CA  . ASN B 1 84  ? -2.836  14.864  117.300 1.00 46.87  ? 103 ASN B CA  1 
ATOM   3364  C C   . ASN B 1 84  ? -2.881  16.381  117.198 1.00 46.90  ? 103 ASN B C   1 
ATOM   3365  O O   . ASN B 1 84  ? -3.969  16.972  117.292 1.00 48.53  ? 103 ASN B O   1 
ATOM   3366  C CB  . ASN B 1 84  ? -2.902  14.468  118.784 1.00 48.27  ? 103 ASN B CB  1 
ATOM   3367  C CG  . ASN B 1 84  ? -3.513  13.073  119.010 1.00 50.09  ? 103 ASN B CG  1 
ATOM   3368  O OD1 . ASN B 1 84  ? -4.440  12.650  118.307 1.00 51.44  ? 103 ASN B OD1 1 
ATOM   3369  N ND2 . ASN B 1 84  ? -2.981  12.353  120.001 1.00 50.43  ? 103 ASN B ND2 1 
ATOM   3370  N N   . LEU B 1 85  ? -1.722  17.016  117.034 1.00 41.71  ? 104 LEU B N   1 
ATOM   3371  C CA  . LEU B 1 85  ? -1.656  18.451  116.793 1.00 42.01  ? 104 LEU B CA  1 
ATOM   3372  C C   . LEU B 1 85  ? -1.825  18.755  115.305 1.00 42.10  ? 104 LEU B C   1 
ATOM   3373  O O   . LEU B 1 85  ? -2.665  19.582  114.929 1.00 43.72  ? 104 LEU B O   1 
ATOM   3374  C CB  . LEU B 1 85  ? -0.336  19.031  117.333 1.00 41.47  ? 104 LEU B CB  1 
ATOM   3375  C CG  . LEU B 1 85  ? -0.278  18.867  118.854 1.00 42.13  ? 104 LEU B CG  1 
ATOM   3376  C CD1 . LEU B 1 85  ? 1.141   19.022  119.318 1.00 41.42  ? 104 LEU B CD1 1 
ATOM   3377  C CD2 . LEU B 1 85  ? -1.226  19.798  119.561 1.00 43.69  ? 104 LEU B CD2 1 
ATOM   3378  N N   . ASN B 1 86  ? -1.038  18.100  114.466 1.00 40.15  ? 105 ASN B N   1 
ATOM   3379  C CA  . ASN B 1 86  ? -1.006  18.387  113.037 1.00 39.93  ? 105 ASN B CA  1 
ATOM   3380  C C   . ASN B 1 86  ? -1.322  17.072  112.357 1.00 39.95  ? 105 ASN B C   1 
ATOM   3381  O O   . ASN B 1 86  ? -0.419  16.226  112.179 1.00 39.15  ? 105 ASN B O   1 
ATOM   3382  C CB  . ASN B 1 86  ? 0.345   18.928  112.571 1.00 38.96  ? 105 ASN B CB  1 
ATOM   3383  C CG  . ASN B 1 86  ? 0.373   19.163  111.087 1.00 38.80  ? 105 ASN B CG  1 
ATOM   3384  O OD1 . ASN B 1 86  ? -0.658  19.013  110.440 1.00 39.46  ? 105 ASN B OD1 1 
ATOM   3385  N ND2 . ASN B 1 86  ? 1.535   19.520  110.535 1.00 38.07  ? 105 ASN B ND2 1 
ATOM   3386  N N   . PRO B 1 87  ? -2.582  16.817  112.010 1.00 39.61  ? 106 PRO B N   1 
ATOM   3387  C CA  . PRO B 1 87  ? -2.907  15.539  111.371 1.00 39.78  ? 106 PRO B CA  1 
ATOM   3388  C C   . PRO B 1 87  ? -2.272  15.387  110.026 1.00 39.11  ? 106 PRO B C   1 
ATOM   3389  O O   . PRO B 1 87  ? -2.273  14.272  109.510 1.00 39.14  ? 106 PRO B O   1 
ATOM   3390  C CB  . PRO B 1 87  ? -4.425  15.558  111.281 1.00 41.06  ? 106 PRO B CB  1 
ATOM   3391  C CG  . PRO B 1 87  ? -4.878  16.830  111.989 1.00 41.71  ? 106 PRO B CG  1 
ATOM   3392  C CD  . PRO B 1 87  ? -3.745  17.681  112.273 1.00 40.68  ? 106 PRO B CD  1 
ATOM   3393  N N   . LYS B 1 88  ? -1.700  16.450  109.458 1.00 40.57  ? 107 LYS B N   1 
ATOM   3394  C CA  . LYS B 1 88  ? -1.019  16.359  108.174 1.00 40.01  ? 107 LYS B CA  1 
ATOM   3395  C C   . LYS B 1 88  ? 0.452   16.032  108.317 1.00 38.90  ? 107 LYS B C   1 
ATOM   3396  O O   . LYS B 1 88  ? 1.159   15.937  107.305 1.00 38.49  ? 107 LYS B O   1 
ATOM   3397  C CB  . LYS B 1 88  ? -1.164  17.658  107.386 1.00 40.41  ? 107 LYS B CB  1 
ATOM   3398  C CG  . LYS B 1 88  ? -2.588  17.961  106.968 1.00 42.47  ? 107 LYS B CG  1 
ATOM   3399  C CD  . LYS B 1 88  ? -2.679  19.269  106.158 1.00 43.42  ? 107 LYS B CD  1 
ATOM   3400  C CE  . LYS B 1 88  ? -3.954  19.300  105.280 1.00 45.89  ? 107 LYS B CE  1 
ATOM   3401  N NZ  . LYS B 1 88  ? -3.907  20.284  104.117 1.00 47.85  ? 107 LYS B NZ  1 
ATOM   3402  N N   . MET B 1 89  ? 0.926   15.826  109.540 1.00 40.50  ? 108 MET B N   1 
ATOM   3403  C CA  . MET B 1 89  ? 2.353   15.660  109.751 1.00 39.65  ? 108 MET B CA  1 
ATOM   3404  C C   . MET B 1 89  ? 2.818   14.263  109.415 1.00 39.34  ? 108 MET B C   1 
ATOM   3405  O O   . MET B 1 89  ? 2.283   13.279  109.930 1.00 40.48  ? 108 MET B O   1 
ATOM   3406  C CB  . MET B 1 89  ? 2.776   15.956  111.193 1.00 40.02  ? 108 MET B CB  1 
ATOM   3407  C CG  . MET B 1 89  ? 4.012   16.806  111.155 1.00 39.67  ? 108 MET B CG  1 
ATOM   3408  S SD  . MET B 1 89  ? 4.522   17.429  112.717 1.00 39.91  ? 108 MET B SD  1 
ATOM   3409  C CE  . MET B 1 89  ? 6.107   18.154  112.283 1.00 39.32  ? 108 MET B CE  1 
ATOM   3410  N N   . LYS B 1 90  ? 3.852   14.196  108.598 1.00 35.87  ? 109 LYS B N   1 
ATOM   3411  C CA  . LYS B 1 90  ? 4.538   12.960  108.291 1.00 35.41  ? 109 LYS B CA  1 
ATOM   3412  C C   . LYS B 1 90  ? 5.694   12.843  109.263 1.00 34.63  ? 109 LYS B C   1 
ATOM   3413  O O   . LYS B 1 90  ? 6.604   13.673  109.251 1.00 34.31  ? 109 LYS B O   1 
ATOM   3414  C CB  . LYS B 1 90  ? 5.053   12.937  106.857 1.00 35.45  ? 109 LYS B CB  1 
ATOM   3415  C CG  . LYS B 1 90  ? 3.999   13.170  105.858 1.00 36.52  ? 109 LYS B CG  1 
ATOM   3416  C CD  . LYS B 1 90  ? 2.987   12.051  105.814 1.00 37.32  ? 109 LYS B CD  1 
ATOM   3417  C CE  . LYS B 1 90  ? 2.205   12.148  104.508 1.00 38.35  ? 109 LYS B CE  1 
ATOM   3418  N NZ  . LYS B 1 90  ? 0.934   11.428  104.659 1.00 39.25  ? 109 LYS B NZ  1 
ATOM   3419  N N   . VAL B 1 91  ? 5.653   11.785  110.071 1.00 34.81  ? 110 VAL B N   1 
ATOM   3420  C CA  . VAL B 1 91  ? 6.634   11.458  111.096 1.00 34.30  ? 110 VAL B CA  1 
ATOM   3421  C C   . VAL B 1 91  ? 7.427   10.235  110.636 1.00 34.12  ? 110 VAL B C   1 
ATOM   3422  O O   . VAL B 1 91  ? 6.875   9.151   110.421 1.00 34.75  ? 110 VAL B O   1 
ATOM   3423  C CB  . VAL B 1 91  ? 5.937   11.209  112.435 1.00 35.03  ? 110 VAL B CB  1 
ATOM   3424  C CG1 . VAL B 1 91  ? 6.938   11.038  113.540 1.00 34.91  ? 110 VAL B CG1 1 
ATOM   3425  C CG2 . VAL B 1 91  ? 5.006   12.359  112.727 1.00 35.72  ? 110 VAL B CG2 1 
ATOM   3426  N N   . ILE B 1 92  ? 8.728   10.414  110.518 1.00 32.94  ? 111 ILE B N   1 
ATOM   3427  C CA  . ILE B 1 92  ? 9.628   9.457   109.924 1.00 32.66  ? 111 ILE B CA  1 
ATOM   3428  C C   . ILE B 1 92  ? 10.429  8.809   111.033 1.00 32.36  ? 111 ILE B C   1 
ATOM   3429  O O   . ILE B 1 92  ? 11.063  9.505   111.843 1.00 32.25  ? 111 ILE B O   1 
ATOM   3430  C CB  . ILE B 1 92  ? 10.557  10.157  108.926 1.00 32.06  ? 111 ILE B CB  1 
ATOM   3431  C CG1 . ILE B 1 92  ? 9.728   10.956  107.945 1.00 32.52  ? 111 ILE B CG1 1 
ATOM   3432  C CG2 . ILE B 1 92  ? 11.479  9.171   108.272 1.00 31.70  ? 111 ILE B CG2 1 
ATOM   3433  C CD1 . ILE B 1 92  ? 8.791   10.150  107.137 1.00 33.69  ? 111 ILE B CD1 1 
ATOM   3434  N N   . PHE B 1 93  ? 10.444  7.475   111.028 1.00 32.17  ? 112 PHE B N   1 
ATOM   3435  C CA  . PHE B 1 93  ? 11.144  6.635   111.984 1.00 32.27  ? 112 PHE B CA  1 
ATOM   3436  C C   . PHE B 1 93  ? 12.582  6.411   111.542 1.00 31.29  ? 112 PHE B C   1 
ATOM   3437  O O   . PHE B 1 93  ? 12.817  5.973   110.415 1.00 31.60  ? 112 PHE B O   1 
ATOM   3438  C CB  . PHE B 1 93  ? 10.374  5.315   112.098 1.00 33.36  ? 112 PHE B CB  1 
ATOM   3439  C CG  . PHE B 1 93  ? 11.096  4.245   112.850 1.00 33.82  ? 112 PHE B CG  1 
ATOM   3440  C CD1 . PHE B 1 93  ? 11.299  4.355   114.206 1.00 34.64  ? 112 PHE B CD1 1 
ATOM   3441  C CD2 . PHE B 1 93  ? 11.560  3.120   112.194 1.00 34.33  ? 112 PHE B CD2 1 
ATOM   3442  C CE1 . PHE B 1 93  ? 11.960  3.378   114.898 1.00 35.15  ? 112 PHE B CE1 1 
ATOM   3443  C CE2 . PHE B 1 93  ? 12.208  2.137   112.880 1.00 35.02  ? 112 PHE B CE2 1 
ATOM   3444  C CZ  . PHE B 1 93  ? 12.418  2.274   114.249 1.00 35.11  ? 112 PHE B CZ  1 
ATOM   3445  N N   . TYR B 1 94  ? 13.536  6.689   112.442 1.00 31.18  ? 113 TYR B N   1 
ATOM   3446  C CA  . TYR B 1 94  ? 14.960  6.474   112.167 1.00 30.84  ? 113 TYR B CA  1 
ATOM   3447  C C   . TYR B 1 94  ? 15.373  5.002   112.330 1.00 31.58  ? 113 TYR B C   1 
ATOM   3448  O O   . TYR B 1 94  ? 15.232  4.399   113.398 1.00 32.38  ? 113 TYR B O   1 
ATOM   3449  C CB  . TYR B 1 94  ? 15.843  7.342   113.078 1.00 30.93  ? 113 TYR B CB  1 
ATOM   3450  C CG  . TYR B 1 94  ? 17.318  7.253   112.753 1.00 30.93  ? 113 TYR B CG  1 
ATOM   3451  C CD1 . TYR B 1 94  ? 18.109  6.244   113.282 1.00 31.44  ? 113 TYR B CD1 1 
ATOM   3452  C CD2 . TYR B 1 94  ? 17.913  8.151   111.887 1.00 30.73  ? 113 TYR B CD2 1 
ATOM   3453  C CE1 . TYR B 1 94  ? 19.475  6.154   112.965 1.00 31.54  ? 113 TYR B CE1 1 
ATOM   3454  C CE2 . TYR B 1 94  ? 19.274  8.070   111.564 1.00 30.94  ? 113 TYR B CE2 1 
ATOM   3455  C CZ  . TYR B 1 94  ? 20.045  7.089   112.121 1.00 31.19  ? 113 TYR B CZ  1 
ATOM   3456  O OH  . TYR B 1 94  ? 21.375  7.021   111.799 1.00 31.84  ? 113 TYR B OH  1 
ATOM   3457  N N   . TRP B 1 95  ? 15.937  4.437   111.282 1.00 28.14  ? 114 TRP B N   1 
ATOM   3458  C CA  . TRP B 1 95  ? 16.272  3.018   111.281 1.00 28.86  ? 114 TRP B CA  1 
ATOM   3459  C C   . TRP B 1 95  ? 17.485  2.872   110.389 1.00 28.81  ? 114 TRP B C   1 
ATOM   3460  O O   . TRP B 1 95  ? 17.378  2.998   109.169 1.00 28.74  ? 114 TRP B O   1 
ATOM   3461  C CB  . TRP B 1 95  ? 15.095  2.169   110.825 1.00 29.90  ? 114 TRP B CB  1 
ATOM   3462  C CG  . TRP B 1 95  ? 15.312  0.677   110.997 1.00 30.94  ? 114 TRP B CG  1 
ATOM   3463  C CD1 . TRP B 1 95  ? 15.034  -0.269  110.075 1.00 31.74  ? 114 TRP B CD1 1 
ATOM   3464  C CD2 . TRP B 1 95  ? 15.874  -0.021  112.131 1.00 31.68  ? 114 TRP B CD2 1 
ATOM   3465  N NE1 . TRP B 1 95  ? 15.399  -1.518  110.546 1.00 33.05  ? 114 TRP B NE1 1 
ATOM   3466  C CE2 . TRP B 1 95  ? 15.895  -1.392  111.809 1.00 33.03  ? 114 TRP B CE2 1 
ATOM   3467  C CE3 . TRP B 1 95  ? 16.382  0.382   113.369 1.00 31.64  ? 114 TRP B CE3 1 
ATOM   3468  C CZ2 . TRP B 1 95  ? 16.381  -2.366  112.685 1.00 34.26  ? 114 TRP B CZ2 1 
ATOM   3469  C CZ3 . TRP B 1 95  ? 16.861  -0.610  114.264 1.00 33.05  ? 114 TRP B CZ3 1 
ATOM   3470  C CH2 . TRP B 1 95  ? 16.864  -1.949  113.914 1.00 34.24  ? 114 TRP B CH2 1 
ATOM   3471  N N   . ASN B 1 96  ? 18.646  2.660   111.011 1.00 30.26  ? 115 ASN B N   1 
ATOM   3472  C CA  . ASN B 1 96  ? 19.917  2.790   110.329 1.00 30.20  ? 115 ASN B CA  1 
ATOM   3473  C C   . ASN B 1 96  ? 20.203  1.566   109.477 1.00 30.81  ? 115 ASN B C   1 
ATOM   3474  O O   . ASN B 1 96  ? 20.239  0.433   109.975 1.00 31.82  ? 115 ASN B O   1 
ATOM   3475  C CB  . ASN B 1 96  ? 21.037  3.003   111.353 1.00 30.45  ? 115 ASN B CB  1 
ATOM   3476  C CG  . ASN B 1 96  ? 22.306  3.534   110.733 1.00 30.80  ? 115 ASN B CG  1 
ATOM   3477  O OD1 . ASN B 1 96  ? 22.980  2.847   109.987 1.00 31.41  ? 115 ASN B OD1 1 
ATOM   3478  N ND2 . ASN B 1 96  ? 22.640  4.766   111.057 1.00 30.85  ? 115 ASN B ND2 1 
ATOM   3479  N N   . THR B 1 97  ? 20.497  1.800   108.210 1.00 30.56  ? 116 THR B N   1 
ATOM   3480  C CA  . THR B 1 97  ? 20.641  0.688   107.282 1.00 31.09  ? 116 THR B CA  1 
ATOM   3481  C C   . THR B 1 97  ? 21.893  -0.147  107.517 1.00 32.19  ? 116 THR B C   1 
ATOM   3482  O O   . THR B 1 97  ? 21.948  -1.289  107.036 1.00 33.30  ? 116 THR B O   1 
ATOM   3483  C CB  . THR B 1 97  ? 20.647  1.224   105.840 1.00 30.59  ? 116 THR B CB  1 
ATOM   3484  O OG1 . THR B 1 97  ? 19.805  2.395   105.744 1.00 29.94  ? 116 THR B OG1 1 
ATOM   3485  C CG2 . THR B 1 97  ? 20.132  0.195   104.835 1.00 31.50  ? 116 THR B CG2 1 
ATOM   3486  N N   . PHE B 1 98  ? 22.872  0.366   108.260 1.00 29.97  ? 117 PHE B N   1 
ATOM   3487  C CA  . PHE B 1 98  ? 24.213  -0.233  108.342 1.00 30.92  ? 117 PHE B CA  1 
ATOM   3488  C C   . PHE B 1 98  ? 24.710  -0.540  109.755 1.00 31.49  ? 117 PHE B C   1 
ATOM   3489  O O   . PHE B 1 98  ? 25.614  -1.381  109.892 1.00 32.68  ? 117 PHE B O   1 
ATOM   3490  C CB  . PHE B 1 98  ? 25.225  0.698   107.658 1.00 31.25  ? 117 PHE B CB  1 
ATOM   3491  C CG  . PHE B 1 98  ? 26.491  0.031   107.169 1.00 32.16  ? 117 PHE B CG  1 
ATOM   3492  C CD1 . PHE B 1 98  ? 26.542  -1.314  106.824 1.00 33.22  ? 117 PHE B CD1 1 
ATOM   3493  C CD2 . PHE B 1 98  ? 27.635  0.809   106.999 1.00 32.76  ? 117 PHE B CD2 1 
ATOM   3494  C CE1 . PHE B 1 98  ? 27.720  -1.873  106.345 1.00 33.87  ? 117 PHE B CE1 1 
ATOM   3495  C CE2 . PHE B 1 98  ? 28.793  0.270   106.531 1.00 33.48  ? 117 PHE B CE2 1 
ATOM   3496  C CZ  . PHE B 1 98  ? 28.851  -1.097  106.208 1.00 33.89  ? 117 PHE B CZ  1 
ATOM   3497  N N   . LEU B 1 99  ? 24.140  0.088   110.802 1.00 33.22  ? 118 LEU B N   1 
ATOM   3498  C CA  . LEU B 1 99  ? 24.658  0.049   112.163 1.00 33.41  ? 118 LEU B CA  1 
ATOM   3499  C C   . LEU B 1 99  ? 23.615  -0.400  113.184 1.00 33.73  ? 118 LEU B C   1 
ATOM   3500  O O   . LEU B 1 99  ? 22.466  0.075   113.205 1.00 33.20  ? 118 LEU B O   1 
ATOM   3501  C CB  . LEU B 1 99  ? 25.192  1.437   112.570 1.00 32.97  ? 118 LEU B CB  1 
ATOM   3502  C CG  . LEU B 1 99  ? 26.184  2.023   111.572 1.00 33.35  ? 118 LEU B CG  1 
ATOM   3503  C CD1 . LEU B 1 99  ? 26.624  3.405   111.999 1.00 33.59  ? 118 LEU B CD1 1 
ATOM   3504  C CD2 . LEU B 1 99  ? 27.397  1.137   111.405 1.00 34.40  ? 118 LEU B CD2 1 
ATOM   3505  N N   . ASP B 1 100 ? 24.078  -1.287  114.074 1.00 33.51  ? 119 ASP B N   1 
ATOM   3506  C CA  . ASP B 1 100 ? 23.320  -1.883  115.172 1.00 33.91  ? 119 ASP B CA  1 
ATOM   3507  C C   . ASP B 1 100 ? 23.384  -0.971  116.395 1.00 33.42  ? 119 ASP B C   1 
ATOM   3508  O O   . ASP B 1 100 ? 24.119  -1.211  117.329 1.00 34.43  ? 119 ASP B O   1 
ATOM   3509  C CB  . ASP B 1 100 ? 23.914  -3.264  115.447 1.00 35.11  ? 119 ASP B CB  1 
ATOM   3510  C CG  . ASP B 1 100 ? 23.410  -3.926  116.742 1.00 35.94  ? 119 ASP B CG  1 
ATOM   3511  O OD1 . ASP B 1 100 ? 22.196  -3.854  117.030 1.00 35.82  ? 119 ASP B OD1 1 
ATOM   3512  O OD2 . ASP B 1 100 ? 24.235  -4.534  117.461 1.00 36.53  ? 119 ASP B OD2 1 
ATOM   3513  N N   . TYR B 1 101 ? 22.589  0.100   116.404 1.00 34.98  ? 120 TYR B N   1 
ATOM   3514  C CA  . TYR B 1 101 ? 22.592  0.969   117.578 1.00 34.76  ? 120 TYR B CA  1 
ATOM   3515  C C   . TYR B 1 101 ? 21.899  0.283   118.754 1.00 35.36  ? 120 TYR B C   1 
ATOM   3516  O O   . TYR B 1 101 ? 20.980  -0.517  118.577 1.00 35.79  ? 120 TYR B O   1 
ATOM   3517  C CB  . TYR B 1 101 ? 21.909  2.308   117.292 1.00 34.23  ? 120 TYR B CB  1 
ATOM   3518  C CG  . TYR B 1 101 ? 22.797  3.271   116.538 1.00 33.73  ? 120 TYR B CG  1 
ATOM   3519  C CD1 . TYR B 1 101 ? 23.791  3.964   117.192 1.00 34.46  ? 120 TYR B CD1 1 
ATOM   3520  C CD2 . TYR B 1 101 ? 22.644  3.465   115.166 1.00 33.58  ? 120 TYR B CD2 1 
ATOM   3521  C CE1 . TYR B 1 101 ? 24.605  4.838   116.530 1.00 34.60  ? 120 TYR B CE1 1 
ATOM   3522  C CE2 . TYR B 1 101 ? 23.471  4.323   114.479 1.00 33.59  ? 120 TYR B CE2 1 
ATOM   3523  C CZ  . TYR B 1 101 ? 24.458  5.024   115.176 1.00 34.13  ? 120 TYR B CZ  1 
ATOM   3524  O OH  . TYR B 1 101 ? 25.298  5.896   114.521 1.00 34.89  ? 120 TYR B OH  1 
ATOM   3525  N N   . SER B 1 102 ? 22.343  0.625   119.978 1.00 36.13  ? 121 SER B N   1 
ATOM   3526  C CA  . SER B 1 102 ? 21.897  -0.093  121.169 1.00 37.16  ? 121 SER B CA  1 
ATOM   3527  C C   . SER B 1 102 ? 20.644  0.499   121.813 1.00 37.02  ? 121 SER B C   1 
ATOM   3528  O O   . SER B 1 102 ? 20.073  -0.129  122.722 1.00 38.38  ? 121 SER B O   1 
ATOM   3529  C CB  . SER B 1 102 ? 23.015  -0.141  122.217 1.00 38.12  ? 121 SER B CB  1 
ATOM   3530  O OG  . SER B 1 102 ? 23.351  1.166   122.669 1.00 38.20  ? 121 SER B OG  1 
ATOM   3531  N N   . MET B 1 103 ? 20.187  1.668   121.377 1.00 37.39  ? 122 MET B N   1 
ATOM   3532  C CA  . MET B 1 103 ? 19.020  2.277   122.004 1.00 37.33  ? 122 MET B CA  1 
ATOM   3533  C C   . MET B 1 103 ? 17.720  1.909   121.301 1.00 37.19  ? 122 MET B C   1 
ATOM   3534  O O   . MET B 1 103 ? 16.707  2.600   121.429 1.00 36.97  ? 122 MET B O   1 
ATOM   3535  C CB  . MET B 1 103 ? 19.216  3.798   122.124 1.00 37.19  ? 122 MET B CB  1 
ATOM   3536  C CG  . MET B 1 103 ? 19.299  4.583   120.865 1.00 37.02  ? 122 MET B CG  1 
ATOM   3537  S SD  . MET B 1 103 ? 20.881  4.534   119.972 1.00 36.79  ? 122 MET B SD  1 
ATOM   3538  C CE  . MET B 1 103 ? 22.029  4.859   121.266 1.00 38.14  ? 122 MET B CE  1 
ATOM   3539  N N   . PHE B 1 104 ? 17.698  0.792   120.606 1.00 36.33  ? 123 PHE B N   1 
ATOM   3540  C CA  . PHE B 1 104 ? 16.478  0.240   120.050 1.00 36.57  ? 123 PHE B CA  1 
ATOM   3541  C C   . PHE B 1 104 ? 16.251  -1.126  120.666 1.00 37.59  ? 123 PHE B C   1 
ATOM   3542  O O   . PHE B 1 104 ? 17.201  -1.855  120.910 1.00 38.14  ? 123 PHE B O   1 
ATOM   3543  C CB  . PHE B 1 104 ? 16.560  0.085   118.524 1.00 36.25  ? 123 PHE B CB  1 
ATOM   3544  C CG  . PHE B 1 104 ? 16.734  1.371   117.774 1.00 34.90  ? 123 PHE B CG  1 
ATOM   3545  C CD1 . PHE B 1 104 ? 17.926  2.039   117.786 1.00 34.41  ? 123 PHE B CD1 1 
ATOM   3546  C CD2 . PHE B 1 104 ? 15.698  1.869   116.997 1.00 34.76  ? 123 PHE B CD2 1 
ATOM   3547  C CE1 . PHE B 1 104 ? 18.098  3.210   117.075 1.00 33.66  ? 123 PHE B CE1 1 
ATOM   3548  C CE2 . PHE B 1 104 ? 15.854  3.042   116.265 1.00 33.76  ? 123 PHE B CE2 1 
ATOM   3549  C CZ  . PHE B 1 104 ? 17.076  3.720   116.321 1.00 33.25  ? 123 PHE B CZ  1 
ATOM   3550  N N   . ALA B 1 105 ? 14.979  -1.463  120.888 1.00 35.37  ? 124 ALA B N   1 
ATOM   3551  C CA  . ALA B 1 105 ? 14.584  -2.817  121.247 1.00 36.78  ? 124 ALA B CA  1 
ATOM   3552  C C   . ALA B 1 105 ? 15.118  -3.864  120.280 1.00 37.01  ? 124 ALA B C   1 
ATOM   3553  O O   . ALA B 1 105 ? 15.413  -4.995  120.680 1.00 38.05  ? 124 ALA B O   1 
ATOM   3554  C CB  . ALA B 1 105 ? 13.060  -2.924  121.285 1.00 37.32  ? 124 ALA B CB  1 
ATOM   3555  N N   . ALA B 1 106 ? 15.219  -3.527  118.999 1.00 34.94  ? 125 ALA B N   1 
ATOM   3556  C CA  . ALA B 1 106 ? 15.726  -4.475  118.013 1.00 35.62  ? 125 ALA B CA  1 
ATOM   3557  C C   . ALA B 1 106 ? 17.171  -4.851  118.262 1.00 35.80  ? 125 ALA B C   1 
ATOM   3558  O O   . ALA B 1 106 ? 17.619  -5.901  117.797 1.00 36.77  ? 125 ALA B O   1 
ATOM   3559  C CB  . ALA B 1 106 ? 15.613  -3.867  116.615 1.00 35.38  ? 125 ALA B CB  1 
ATOM   3560  N N   . HIS B 1 107 ? 17.911  -4.006  118.981 1.00 34.50  ? 126 HIS B N   1 
ATOM   3561  C CA  . HIS B 1 107 ? 19.306  -4.287  119.277 1.00 34.88  ? 126 HIS B CA  1 
ATOM   3562  C C   . HIS B 1 107 ? 19.452  -5.634  120.003 1.00 36.12  ? 126 HIS B C   1 
ATOM   3563  O O   . HIS B 1 107 ? 20.393  -6.410  119.747 1.00 36.61  ? 126 HIS B O   1 
ATOM   3564  C CB  . HIS B 1 107 ? 19.873  -3.128  120.101 1.00 34.03  ? 126 HIS B CB  1 
ATOM   3565  C CG  . HIS B 1 107 ? 21.242  -3.387  120.630 1.00 34.42  ? 126 HIS B CG  1 
ATOM   3566  N ND1 . HIS B 1 107 ? 22.344  -3.481  119.806 1.00 34.31  ? 126 HIS B ND1 1 
ATOM   3567  C CD2 . HIS B 1 107 ? 21.688  -3.612  121.888 1.00 35.18  ? 126 HIS B CD2 1 
ATOM   3568  C CE1 . HIS B 1 107 ? 23.409  -3.752  120.538 1.00 34.79  ? 126 HIS B CE1 1 
ATOM   3569  N NE2 . HIS B 1 107 ? 23.041  -3.821  121.804 1.00 35.25  ? 126 HIS B NE2 1 
ATOM   3570  N N   . LYS B 1 108 ? 18.538  -5.935  120.910 1.00 36.29  ? 127 LYS B N   1 
ATOM   3571  C CA  . LYS B 1 108 ? 18.672  -7.173  121.667 1.00 37.24  ? 127 LYS B CA  1 
ATOM   3572  C C   . LYS B 1 108 ? 18.116  -8.366  120.897 1.00 38.39  ? 127 LYS B C   1 
ATOM   3573  O O   . LYS B 1 108 ? 18.391  -9.521  121.259 1.00 39.56  ? 127 LYS B O   1 
ATOM   3574  C CB  . LYS B 1 108 ? 18.070  -6.958  123.065 1.00 37.44  ? 127 LYS B CB  1 
ATOM   3575  C CG  . LYS B 1 108 ? 16.631  -7.261  123.276 1.00 37.97  ? 127 LYS B CG  1 
ATOM   3576  C CD  . LYS B 1 108 ? 16.118  -6.685  124.653 1.00 38.06  ? 127 LYS B CD  1 
ATOM   3577  C CE  . LYS B 1 108 ? 16.512  -5.220  124.937 1.00 37.40  ? 127 LYS B CE  1 
ATOM   3578  N NZ  . LYS B 1 108 ? 15.816  -4.110  124.108 1.00 36.65  ? 127 LYS B NZ  1 
ATOM   3579  N N   . GLU B 1 109 ? 17.441  -8.120  119.778 1.00 35.32  ? 128 GLU B N   1 
ATOM   3580  C CA  . GLU B 1 109 ? 17.119  -9.194  118.846 1.00 36.07  ? 128 GLU B CA  1 
ATOM   3581  C C   . GLU B 1 109 ? 18.317  -9.464  117.939 1.00 36.19  ? 128 GLU B C   1 
ATOM   3582  O O   . GLU B 1 109 ? 18.721  -10.612 117.759 1.00 37.21  ? 128 GLU B O   1 
ATOM   3583  C CB  . GLU B 1 109 ? 15.842  -8.824  118.076 1.00 35.96  ? 128 GLU B CB  1 
ATOM   3584  N N   . TYR B 1 110 ? 18.955  -8.432  117.409 1.00 33.00  ? 129 TYR B N   1 
ATOM   3585  C CA  . TYR B 1 110 ? 20.130  -8.681  116.575 1.00 33.29  ? 129 TYR B CA  1 
ATOM   3586  C C   . TYR B 1 110 ? 21.165  -9.456  117.369 1.00 34.10  ? 129 TYR B C   1 
ATOM   3587  O O   . TYR B 1 110 ? 21.995  -10.170 116.812 1.00 34.51  ? 129 TYR B O   1 
ATOM   3588  C CB  . TYR B 1 110 ? 20.695  -7.352  116.041 1.00 31.87  ? 129 TYR B CB  1 
ATOM   3589  C CG  . TYR B 1 110 ? 21.774  -7.528  114.998 1.00 32.26  ? 129 TYR B CG  1 
ATOM   3590  C CD1 . TYR B 1 110 ? 21.480  -7.981  113.742 1.00 32.71  ? 129 TYR B CD1 1 
ATOM   3591  C CD2 . TYR B 1 110 ? 23.082  -7.249  115.278 1.00 31.70  ? 129 TYR B CD2 1 
ATOM   3592  C CE1 . TYR B 1 110 ? 22.442  -8.145  112.797 1.00 33.21  ? 129 TYR B CE1 1 
ATOM   3593  C CE2 . TYR B 1 110 ? 24.068  -7.424  114.325 1.00 32.26  ? 129 TYR B CE2 1 
ATOM   3594  C CZ  . TYR B 1 110 ? 23.731  -7.875  113.085 1.00 32.56  ? 129 TYR B CZ  1 
ATOM   3595  O OH  . TYR B 1 110 ? 24.677  -8.039  112.110 1.00 32.90  ? 129 TYR B OH  1 
ATOM   3596  N N   . ALA B 1 111 ? 21.122  -9.320  118.676 1.00 35.27  ? 130 ALA B N   1 
ATOM   3597  C CA  . ALA B 1 111 ? 22.155  -9.908  119.507 1.00 35.67  ? 130 ALA B CA  1 
ATOM   3598  C C   . ALA B 1 111 ? 21.987  -11.414 119.578 1.00 36.87  ? 130 ALA B C   1 
ATOM   3599  O O   . ALA B 1 111 ? 22.963  -12.140 119.799 1.00 37.61  ? 130 ALA B O   1 
ATOM   3600  C CB  . ALA B 1 111 ? 22.098  -9.277  120.899 1.00 35.45  ? 130 ALA B CB  1 
ATOM   3601  N N   . LYS B 1 112 ? 20.759  -11.900 119.434 1.00 35.98  ? 131 LYS B N   1 
ATOM   3602  C CA  . LYS B 1 112 ? 20.491  -13.332 119.477 1.00 37.24  ? 131 LYS B CA  1 
ATOM   3603  C C   . LYS B 1 112 ? 20.644  -13.983 118.109 1.00 38.01  ? 131 LYS B C   1 
ATOM   3604  O O   . LYS B 1 112 ? 20.209  -15.111 117.947 1.00 39.09  ? 131 LYS B O   1 
ATOM   3605  C CB  . LYS B 1 112 ? 19.089  -13.584 120.040 1.00 37.36  ? 131 LYS B CB  1 
ATOM   3606  N N   . HIS B 1 113 ? 21.262  -13.317 117.126 1.00 37.33  ? 132 HIS B N   1 
ATOM   3607  C CA  . HIS B 1 113 ? 21.435  -13.872 115.776 1.00 37.78  ? 132 HIS B CA  1 
ATOM   3608  C C   . HIS B 1 113 ? 22.883  -13.761 115.311 1.00 37.94  ? 132 HIS B C   1 
ATOM   3609  O O   . HIS B 1 113 ? 23.179  -13.172 114.268 1.00 36.91  ? 132 HIS B O   1 
ATOM   3610  C CB  . HIS B 1 113 ? 20.532  -13.180 114.756 1.00 37.79  ? 132 HIS B CB  1 
ATOM   3611  C CG  . HIS B 1 113 ? 19.088  -13.467 114.942 1.00 38.29  ? 132 HIS B CG  1 
ATOM   3612  N ND1 . HIS B 1 113 ? 18.495  -14.624 114.489 1.00 39.29  ? 132 HIS B ND1 1 
ATOM   3613  C CD2 . HIS B 1 113 ? 18.106  -12.725 115.501 1.00 38.07  ? 132 HIS B CD2 1 
ATOM   3614  C CE1 . HIS B 1 113 ? 17.206  -14.595 114.792 1.00 39.57  ? 132 HIS B CE1 1 
ATOM   3615  N NE2 . HIS B 1 113 ? 16.949  -13.461 115.418 1.00 39.10  ? 132 HIS B NE2 1 
ATOM   3616  N N   . PRO B 1 114 ? 23.802  -14.406 116.015 1.00 38.97  ? 133 PRO B N   1 
ATOM   3617  C CA  . PRO B 1 114 ? 25.221  -14.244 115.683 1.00 39.12  ? 133 PRO B CA  1 
ATOM   3618  C C   . PRO B 1 114 ? 25.640  -14.874 114.375 1.00 39.45  ? 133 PRO B C   1 
ATOM   3619  O O   . PRO B 1 114 ? 26.686  -14.473 113.848 1.00 39.02  ? 133 PRO B O   1 
ATOM   3620  C CB  . PRO B 1 114 ? 25.925  -14.893 116.868 1.00 40.18  ? 133 PRO B CB  1 
ATOM   3621  C CG  . PRO B 1 114 ? 24.893  -15.848 117.418 1.00 40.72  ? 133 PRO B CG  1 
ATOM   3622  C CD  . PRO B 1 114 ? 23.593  -15.173 117.250 1.00 39.74  ? 133 PRO B CD  1 
ATOM   3623  N N   . GLN B 1 115 ? 24.891  -15.843 113.829 1.00 39.26  ? 134 GLN B N   1 
ATOM   3624  C CA  . GLN B 1 115 ? 25.170  -16.333 112.481 1.00 39.79  ? 134 GLN B CA  1 
ATOM   3625  C C   . GLN B 1 115 ? 25.071  -15.227 111.432 1.00 38.67  ? 134 GLN B C   1 
ATOM   3626  O O   . GLN B 1 115 ? 25.709  -15.338 110.383 1.00 39.16  ? 134 GLN B O   1 
ATOM   3627  C CB  . GLN B 1 115 ? 24.203  -17.458 112.168 1.00 41.54  ? 134 GLN B CB  1 
ATOM   3628  C CG  . GLN B 1 115 ? 22.775  -17.009 112.145 1.00 42.55  ? 134 GLN B CG  1 
ATOM   3629  C CD  . GLN B 1 115 ? 22.088  -17.213 113.461 1.00 42.90  ? 134 GLN B CD  1 
ATOM   3630  O OE1 . GLN B 1 115 ? 22.703  -17.049 114.515 1.00 41.80  ? 134 GLN B OE1 1 
ATOM   3631  N NE2 . GLN B 1 115 ? 20.783  -17.515 113.414 1.00 43.42  ? 134 GLN B NE2 1 
ATOM   3632  N N   . TRP B 1 116 ? 24.336  -14.141 111.704 1.00 37.33  ? 135 TRP B N   1 
ATOM   3633  C CA  . TRP B 1 116 ? 24.215  -13.071 110.710 1.00 36.86  ? 135 TRP B CA  1 
ATOM   3634  C C   . TRP B 1 116 ? 25.420  -12.153 110.697 1.00 35.83  ? 135 TRP B C   1 
ATOM   3635  O O   . TRP B 1 116 ? 25.742  -11.599 109.648 1.00 35.32  ? 135 TRP B O   1 
ATOM   3636  C CB  . TRP B 1 116 ? 22.987  -12.192 110.954 1.00 36.55  ? 135 TRP B CB  1 
ATOM   3637  C CG  . TRP B 1 116 ? 21.715  -12.916 110.843 1.00 37.03  ? 135 TRP B CG  1 
ATOM   3638  C CD1 . TRP B 1 116 ? 21.510  -14.114 110.260 1.00 37.70  ? 135 TRP B CD1 1 
ATOM   3639  C CD2 . TRP B 1 116 ? 20.446  -12.481 111.325 1.00 36.54  ? 135 TRP B CD2 1 
ATOM   3640  N NE1 . TRP B 1 116 ? 20.191  -14.466 110.351 1.00 37.90  ? 135 TRP B NE1 1 
ATOM   3641  C CE2 . TRP B 1 116 ? 19.514  -13.481 111.010 1.00 37.27  ? 135 TRP B CE2 1 
ATOM   3642  C CE3 . TRP B 1 116 ? 20.008  -11.348 112.002 1.00 35.93  ? 135 TRP B CE3 1 
ATOM   3643  C CZ2 . TRP B 1 116 ? 18.169  -13.385 111.337 1.00 37.27  ? 135 TRP B CZ2 1 
ATOM   3644  C CZ3 . TRP B 1 116 ? 18.662  -11.268 112.347 1.00 36.11  ? 135 TRP B CZ3 1 
ATOM   3645  C CH2 . TRP B 1 116 ? 17.760  -12.281 112.007 1.00 36.75  ? 135 TRP B CH2 1 
ATOM   3646  N N   . TRP B 1 117 ? 26.111  -12.022 111.836 1.00 36.13  ? 136 TRP B N   1 
ATOM   3647  C CA  . TRP B 1 117 ? 26.989  -10.884 112.080 1.00 34.76  ? 136 TRP B CA  1 
ATOM   3648  C C   . TRP B 1 117 ? 28.114  -10.811 111.053 1.00 35.01  ? 136 TRP B C   1 
ATOM   3649  O O   . TRP B 1 117 ? 28.784  -11.798 110.764 1.00 36.06  ? 136 TRP B O   1 
ATOM   3650  C CB  . TRP B 1 117 ? 27.583  -10.981 113.487 1.00 35.01  ? 136 TRP B CB  1 
ATOM   3651  C CG  . TRP B 1 117 ? 26.591  -10.947 114.601 1.00 35.13  ? 136 TRP B CG  1 
ATOM   3652  C CD1 . TRP B 1 117 ? 25.255  -10.637 114.524 1.00 34.94  ? 136 TRP B CD1 1 
ATOM   3653  C CD2 . TRP B 1 117 ? 26.859  -11.231 115.970 1.00 35.27  ? 136 TRP B CD2 1 
ATOM   3654  N NE1 . TRP B 1 117 ? 24.679  -10.709 115.776 1.00 35.13  ? 136 TRP B NE1 1 
ATOM   3655  C CE2 . TRP B 1 117 ? 25.642  -11.088 116.678 1.00 35.33  ? 136 TRP B CE2 1 
ATOM   3656  C CE3 . TRP B 1 117 ? 28.011  -11.582 116.675 1.00 36.13  ? 136 TRP B CE3 1 
ATOM   3657  C CZ2 . TRP B 1 117 ? 25.546  -11.329 118.055 1.00 36.10  ? 136 TRP B CZ2 1 
ATOM   3658  C CZ3 . TRP B 1 117 ? 27.917  -11.811 118.050 1.00 36.68  ? 136 TRP B CZ3 1 
ATOM   3659  C CH2 . TRP B 1 117 ? 26.694  -11.679 118.722 1.00 36.92  ? 136 TRP B CH2 1 
ATOM   3660  N N   . LEU B 1 118 ? 28.349  -9.620  110.528 1.00 35.80  ? 137 LEU B N   1 
ATOM   3661  C CA  . LEU B 1 118 ? 29.314  -9.470  109.449 1.00 35.83  ? 137 LEU B CA  1 
ATOM   3662  C C   . LEU B 1 118 ? 30.733  -9.607  109.969 1.00 35.98  ? 137 LEU B C   1 
ATOM   3663  O O   . LEU B 1 118 ? 31.074  -9.077  111.027 1.00 35.44  ? 137 LEU B O   1 
ATOM   3664  C CB  . LEU B 1 118 ? 29.145  -8.108  108.787 1.00 34.81  ? 137 LEU B CB  1 
ATOM   3665  C CG  . LEU B 1 118 ? 30.079  -7.697  107.665 1.00 34.54  ? 137 LEU B CG  1 
ATOM   3666  C CD1 . LEU B 1 118 ? 30.064  -8.604  106.517 1.00 35.32  ? 137 LEU B CD1 1 
ATOM   3667  C CD2 . LEU B 1 118 ? 29.591  -6.295  107.244 1.00 33.72  ? 137 LEU B CD2 1 
ATOM   3668  N N   . ARG B 1 119 ? 31.572  -10.290 109.198 1.00 39.17  ? 138 ARG B N   1 
ATOM   3669  C CA  . ARG B 1 119 ? 32.974  -10.443 109.548 1.00 39.44  ? 138 ARG B CA  1 
ATOM   3670  C C   . ARG B 1 119 ? 33.841  -10.042 108.368 1.00 38.98  ? 138 ARG B C   1 
ATOM   3671  O O   . ARG B 1 119 ? 33.429  -10.136 107.210 1.00 39.14  ? 138 ARG B O   1 
ATOM   3672  C CB  . ARG B 1 119 ? 33.345  -11.901 109.992 1.00 41.06  ? 138 ARG B CB  1 
ATOM   3673  C CG  . ARG B 1 119 ? 32.501  -12.436 111.139 1.00 41.50  ? 138 ARG B CG  1 
ATOM   3674  C CD  . ARG B 1 119 ? 33.163  -13.676 111.841 1.00 42.89  ? 138 ARG B CD  1 
ATOM   3675  N NE  . ARG B 1 119 ? 32.186  -14.289 112.738 1.00 43.24  ? 138 ARG B NE  1 
ATOM   3676  C CZ  . ARG B 1 119 ? 32.149  -14.104 114.047 1.00 43.06  ? 138 ARG B CZ  1 
ATOM   3677  N NH1 . ARG B 1 119 ? 33.160  -13.553 114.685 1.00 42.59  ? 138 ARG B NH1 1 
ATOM   3678  N NH2 . ARG B 1 119 ? 31.051  -14.450 114.721 1.00 43.59  ? 138 ARG B NH2 1 
ATOM   3679  N N   . THR B 1 120 ? 35.037  -9.559  108.696 1.00 43.30  ? 139 THR B N   1 
ATOM   3680  C CA  . THR B 1 120 ? 36.057  -9.230  107.723 1.00 43.03  ? 139 THR B CA  1 
ATOM   3681  C C   . THR B 1 120 ? 36.696  -10.502 107.176 1.00 43.95  ? 139 THR B C   1 
ATOM   3682  O O   . THR B 1 120 ? 36.431  -11.613 107.625 1.00 45.00  ? 139 THR B O   1 
ATOM   3683  C CB  . THR B 1 120 ? 37.125  -8.357  108.381 1.00 43.29  ? 139 THR B CB  1 
ATOM   3684  O OG1 . THR B 1 120 ? 37.813  -9.121  109.396 1.00 44.38  ? 139 THR B OG1 1 
ATOM   3685  C CG2 . THR B 1 120 ? 36.466  -7.137  109.012 1.00 42.75  ? 139 THR B CG2 1 
ATOM   3686  N N   . THR B 1 121 ? 37.569  -10.322 106.186 1.00 45.70  ? 140 THR B N   1 
ATOM   3687  C CA  . THR B 1 121 ? 38.294  -11.453 105.630 1.00 46.66  ? 140 THR B CA  1 
ATOM   3688  C C   . THR B 1 121 ? 39.216  -12.087 106.653 1.00 47.78  ? 140 THR B C   1 
ATOM   3689  O O   . THR B 1 121 ? 39.605  -13.244 106.477 1.00 49.23  ? 140 THR B O   1 
ATOM   3690  C CB  . THR B 1 121 ? 39.084  -11.013 104.403 1.00 46.32  ? 140 THR B CB  1 
ATOM   3691  O OG1 . THR B 1 121 ? 40.024  -10.001 104.759 1.00 46.16  ? 140 THR B OG1 1 
ATOM   3692  C CG2 . THR B 1 121 ? 38.174  -10.427 103.350 1.00 45.82  ? 140 THR B CG2 1 
ATOM   3693  N N   . THR B 1 122 ? 39.563  -11.365 107.722 1.00 46.51  ? 141 THR B N   1 
ATOM   3694  C CA  . THR B 1 122 ? 40.380  -11.897 108.810 1.00 48.76  ? 141 THR B CA  1 
ATOM   3695  C C   . THR B 1 122 ? 39.570  -12.637 109.863 1.00 49.23  ? 141 THR B C   1 
ATOM   3696  O O   . THR B 1 122 ? 40.153  -13.146 110.821 1.00 51.12  ? 141 THR B O   1 
ATOM   3697  C CB  . THR B 1 122 ? 41.113  -10.759 109.538 1.00 49.16  ? 141 THR B CB  1 
ATOM   3698  O OG1 . THR B 1 122 ? 40.146  -9.918  110.216 1.00 48.30  ? 141 THR B OG1 1 
ATOM   3699  C CG2 . THR B 1 122 ? 41.933  -9.943  108.552 1.00 49.17  ? 141 THR B CG2 1 
ATOM   3700  N N   . GLY B 1 123 ? 38.243  -12.629 109.765 1.00 47.67  ? 142 GLY B N   1 
ATOM   3701  C CA  . GLY B 1 123 ? 37.406  -13.275 110.749 1.00 47.75  ? 142 GLY B CA  1 
ATOM   3702  C C   . GLY B 1 123 ? 36.961  -12.407 111.912 1.00 47.31  ? 142 GLY B C   1 
ATOM   3703  O O   . GLY B 1 123 ? 36.027  -12.801 112.629 1.00 47.81  ? 142 GLY B O   1 
ATOM   3704  N N   . GLU B 1 124 ? 37.610  -11.254 112.139 1.00 42.33  ? 143 GLU B N   1 
ATOM   3705  C CA  . GLU B 1 124 ? 37.164  -10.354 113.188 1.00 42.33  ? 143 GLU B CA  1 
ATOM   3706  C C   . GLU B 1 124 ? 35.780  -9.859  112.816 1.00 40.48  ? 143 GLU B C   1 
ATOM   3707  O O   . GLU B 1 124 ? 35.486  -9.627  111.644 1.00 39.88  ? 143 GLU B O   1 
ATOM   3708  C CB  . GLU B 1 124 ? 38.135  -9.194  113.341 1.00 42.98  ? 143 GLU B CB  1 
ATOM   3709  N N   . LEU B 1 125 ? 34.914  -9.760  113.812 1.00 40.12  ? 144 LEU B N   1 
ATOM   3710  C CA  . LEU B 1 125 ? 33.623  -9.108  113.624 1.00 38.88  ? 144 LEU B CA  1 
ATOM   3711  C C   . LEU B 1 125 ? 33.806  -7.677  113.139 1.00 37.67  ? 144 LEU B C   1 
ATOM   3712  O O   . LEU B 1 125 ? 34.588  -6.927  113.706 1.00 38.19  ? 144 LEU B O   1 
ATOM   3713  C CB  . LEU B 1 125 ? 32.868  -9.055  114.949 1.00 39.42  ? 144 LEU B CB  1 
ATOM   3714  C CG  . LEU B 1 125 ? 32.238  -10.320 115.479 1.00 40.96  ? 144 LEU B CG  1 
ATOM   3715  C CD1 . LEU B 1 125 ? 31.809  -10.112 116.874 1.00 41.61  ? 144 LEU B CD1 1 
ATOM   3716  C CD2 . LEU B 1 125 ? 31.054  -10.618 114.573 1.00 40.73  ? 144 LEU B CD2 1 
ATOM   3717  N N   . ASP B 1 126 ? 33.025  -7.263  112.157 1.00 38.96  ? 145 ASP B N   1 
ATOM   3718  C CA  . ASP B 1 126 ? 33.117  -5.894  111.652 1.00 37.93  ? 145 ASP B CA  1 
ATOM   3719  C C   . ASP B 1 126 ? 32.306  -4.927  112.522 1.00 37.51  ? 145 ASP B C   1 
ATOM   3720  O O   . ASP B 1 126 ? 31.075  -4.961  112.542 1.00 36.82  ? 145 ASP B O   1 
ATOM   3721  C CB  . ASP B 1 126 ? 32.674  -5.852  110.194 1.00 37.43  ? 145 ASP B CB  1 
ATOM   3722  C CG  . ASP B 1 126 ? 32.926  -4.497  109.541 1.00 37.25  ? 145 ASP B CG  1 
ATOM   3723  O OD1 . ASP B 1 126 ? 33.035  -3.511  110.289 1.00 37.02  ? 145 ASP B OD1 1 
ATOM   3724  O OD2 . ASP B 1 126 ? 32.997  -4.409  108.289 1.00 37.36  ? 145 ASP B OD2 1 
ATOM   3725  N N   . ARG B 1 127 ? 33.009  -4.052  113.256 1.00 42.04  ? 146 ARG B N   1 
ATOM   3726  C CA  . ARG B 1 127 ? 32.374  -3.011  114.068 1.00 42.02  ? 146 ARG B CA  1 
ATOM   3727  C C   . ARG B 1 127 ? 32.966  -1.663  113.712 1.00 42.37  ? 146 ARG B C   1 
ATOM   3728  O O   . ARG B 1 127 ? 34.167  -1.563  113.477 1.00 43.57  ? 146 ARG B O   1 
ATOM   3729  C CB  . ARG B 1 127 ? 32.569  -3.235  115.596 1.00 43.22  ? 146 ARG B CB  1 
ATOM   3730  C CG  . ARG B 1 127 ? 32.115  -4.589  116.065 1.00 43.57  ? 146 ARG B CG  1 
ATOM   3731  C CD  . ARG B 1 127 ? 31.846  -4.684  117.552 1.00 45.05  ? 146 ARG B CD  1 
ATOM   3732  N NE  . ARG B 1 127 ? 32.341  -5.960  118.057 1.00 45.81  ? 146 ARG B NE  1 
ATOM   3733  C CZ  . ARG B 1 127 ? 33.633  -6.230  118.190 1.00 47.13  ? 146 ARG B CZ  1 
ATOM   3734  N NH1 . ARG B 1 127 ? 34.557  -5.334  117.867 1.00 48.21  ? 146 ARG B NH1 1 
ATOM   3735  N NH2 . ARG B 1 127 ? 34.009  -7.414  118.676 1.00 48.25  ? 146 ARG B NH2 1 
ATOM   3736  N N   . LYS B 1 128 ? 32.143  -0.628  113.696 1.00 42.98  ? 147 LYS B N   1 
ATOM   3737  C CA  . LYS B 1 128 ? 32.621  0.749   113.626 1.00 43.87  ? 147 LYS B CA  1 
ATOM   3738  C C   . LYS B 1 128 ? 32.923  1.271   115.033 1.00 45.44  ? 147 LYS B C   1 
ATOM   3739  O O   . LYS B 1 128 ? 32.329  0.828   116.020 1.00 45.79  ? 147 LYS B O   1 
ATOM   3740  C CB  . LYS B 1 128 ? 31.595  1.665   112.936 1.00 43.20  ? 147 LYS B CB  1 
ATOM   3741  C CG  . LYS B 1 128 ? 32.163  3.086   112.650 1.00 45.28  ? 147 LYS B CG  1 
ATOM   3742  C CD  . LYS B 1 128 ? 31.238  4.044   111.909 1.00 44.97  ? 147 LYS B CD  1 
ATOM   3743  C CE  . LYS B 1 128 ? 30.145  4.624   112.786 1.00 45.04  ? 147 LYS B CE  1 
ATOM   3744  N NZ  . LYS B 1 128 ? 29.513  5.898   112.151 1.00 45.08  ? 147 LYS B NZ  1 
ATOM   3745  N N   . LYS B 1 129 ? 33.862  2.219   115.115 1.00 47.15  ? 148 LYS B N   1 
ATOM   3746  C CA  . LYS B 1 129 ? 34.344  2.831   116.358 1.00 49.25  ? 148 LYS B CA  1 
ATOM   3747  C C   . LYS B 1 129 ? 34.880  1.785   117.327 1.00 51.06  ? 148 LYS B C   1 
ATOM   3748  O O   . LYS B 1 129 ? 35.253  2.123   118.466 1.00 54.00  ? 148 LYS B O   1 
ATOM   3749  C CB  . LYS B 1 129 ? 33.267  3.688   117.051 1.00 49.25  ? 148 LYS B CB  1 
ATOM   3750  N N   . GLY B 1 130 ? 34.954  0.526   116.891 1.00 51.07  ? 149 GLY B N   1 
ATOM   3751  C CA  . GLY B 1 130 ? 35.402  -0.577  117.714 1.00 52.35  ? 149 GLY B CA  1 
ATOM   3752  C C   . GLY B 1 130 ? 34.294  -1.257  118.511 1.00 52.45  ? 149 GLY B C   1 
ATOM   3753  O O   . GLY B 1 130 ? 34.430  -2.435  118.886 1.00 53.69  ? 149 GLY B O   1 
ATOM   3754  N N   . GLN B 1 131 ? 33.218  -0.529  118.810 1.00 51.03  ? 150 GLN B N   1 
ATOM   3755  C CA  . GLN B 1 131 ? 32.089  -1.118  119.532 1.00 51.00  ? 150 GLN B CA  1 
ATOM   3756  C C   . GLN B 1 131 ? 30.890  -0.465  118.864 1.00 49.36  ? 150 GLN B C   1 
ATOM   3757  O O   . GLN B 1 131 ? 30.603  0.709   119.186 1.00 50.15  ? 150 GLN B O   1 
ATOM   3758  C CB  . GLN B 1 131 ? 32.129  -0.867  121.039 1.00 53.05  ? 150 GLN B CB  1 
ATOM   3759  N N   . LEU B 1 132 ? 30.270  -1.219  117.902 1.00 44.51  ? 151 LEU B N   1 
ATOM   3760  C CA  . LEU B 1 132 ? 29.072  -0.897  117.115 1.00 42.67  ? 151 LEU B CA  1 
ATOM   3761  C C   . LEU B 1 132 ? 29.042  -1.736  115.806 1.00 41.41  ? 151 LEU B C   1 
ATOM   3762  O O   . LEU B 1 132 ? 29.651  -1.374  114.788 1.00 41.38  ? 151 LEU B O   1 
ATOM   3763  C CB  . LEU B 1 132 ? 29.020  0.615   116.874 1.00 42.52  ? 151 LEU B CB  1 
ATOM   3764  C CG  . LEU B 1 132 ? 27.797  1.249   116.183 1.00 41.57  ? 151 LEU B CG  1 
ATOM   3765  C CD1 . LEU B 1 132 ? 26.502  1.202   117.009 1.00 41.95  ? 151 LEU B CD1 1 
ATOM   3766  C CD2 . LEU B 1 132 ? 28.067  2.724   115.864 1.00 41.54  ? 151 LEU B CD2 1 
ATOM   3767  N N   . MET B 1 133 ? 28.329  -2.879  115.825 1.00 36.96  ? 152 MET B N   1 
ATOM   3768  C CA  . MET B 1 133 ? 28.386  -3.844  114.723 1.00 36.41  ? 152 MET B CA  1 
ATOM   3769  C C   . MET B 1 133 ? 27.755  -3.283  113.442 1.00 35.42  ? 152 MET B C   1 
ATOM   3770  O O   . MET B 1 133 ? 26.788  -2.513  113.489 1.00 34.87  ? 152 MET B O   1 
ATOM   3771  C CB  . MET B 1 133 ? 27.658  -5.152  115.092 1.00 37.79  ? 152 MET B CB  1 
ATOM   3772  C CG  . MET B 1 133 ? 28.535  -6.233  115.725 1.00 39.70  ? 152 MET B CG  1 
ATOM   3773  S SD  . MET B 1 133 ? 27.734  -7.751  116.214 1.00 40.32  ? 152 MET B SD  1 
ATOM   3774  C CE  . MET B 1 133 ? 26.340  -7.232  117.220 1.00 40.74  ? 152 MET B CE  1 
ATOM   3775  N N   . ARG B 1 134 ? 28.293  -3.719  112.291 1.00 34.40  ? 153 ARG B N   1 
ATOM   3776  C CA  . ARG B 1 134 ? 27.784  -3.341  110.984 1.00 33.53  ? 153 ARG B CA  1 
ATOM   3777  C C   . ARG B 1 134 ? 27.159  -4.544  110.292 1.00 34.00  ? 153 ARG B C   1 
ATOM   3778  O O   . ARG B 1 134 ? 27.696  -5.661  110.339 1.00 35.32  ? 153 ARG B O   1 
ATOM   3779  C CB  . ARG B 1 134 ? 28.885  -2.761  110.076 1.00 33.75  ? 153 ARG B CB  1 
ATOM   3780  C CG  . ARG B 1 134 ? 29.624  -1.582  110.645 1.00 33.87  ? 153 ARG B CG  1 
ATOM   3781  C CD  . ARG B 1 134 ? 30.394  -0.791  109.611 1.00 34.14  ? 153 ARG B CD  1 
ATOM   3782  N NE  . ARG B 1 134 ? 31.427  -1.558  108.943 1.00 34.71  ? 153 ARG B NE  1 
ATOM   3783  C CZ  . ARG B 1 134 ? 32.118  -1.129  107.890 1.00 35.27  ? 153 ARG B CZ  1 
ATOM   3784  N NH1 . ARG B 1 134 ? 32.002  0.107   107.440 1.00 35.22  ? 153 ARG B NH1 1 
ATOM   3785  N NH2 . ARG B 1 134 ? 32.927  -1.975  107.245 1.00 35.79  ? 153 ARG B NH2 1 
ATOM   3786  N N   . TYR B 1 135 ? 26.063  -4.288  109.586 1.00 32.10  ? 154 TYR B N   1 
ATOM   3787  C CA  . TYR B 1 135 ? 25.198  -5.346  109.103 1.00 32.94  ? 154 TYR B CA  1 
ATOM   3788  C C   . TYR B 1 135 ? 25.680  -5.930  107.786 1.00 33.25  ? 154 TYR B C   1 
ATOM   3789  O O   . TYR B 1 135 ? 26.210  -5.209  106.934 1.00 32.87  ? 154 TYR B O   1 
ATOM   3790  C CB  . TYR B 1 135 ? 23.794  -4.814  108.885 1.00 32.24  ? 154 TYR B CB  1 
ATOM   3791  C CG  . TYR B 1 135 ? 23.031  -4.304  110.066 1.00 31.96  ? 154 TYR B CG  1 
ATOM   3792  C CD1 . TYR B 1 135 ? 23.021  -4.973  111.292 1.00 33.04  ? 154 TYR B CD1 1 
ATOM   3793  C CD2 . TYR B 1 135 ? 22.277  -3.166  109.945 1.00 30.89  ? 154 TYR B CD2 1 
ATOM   3794  C CE1 . TYR B 1 135 ? 22.268  -4.478  112.350 1.00 32.98  ? 154 TYR B CE1 1 
ATOM   3795  C CE2 . TYR B 1 135 ? 21.538  -2.697  110.973 1.00 30.69  ? 154 TYR B CE2 1 
ATOM   3796  C CZ  . TYR B 1 135 ? 21.523  -3.332  112.155 1.00 31.68  ? 154 TYR B CZ  1 
ATOM   3797  O OH  . TYR B 1 135 ? 20.727  -2.790  113.121 1.00 32.04  ? 154 TYR B OH  1 
ATOM   3798  N N   . ASP B 1 136 ? 25.472  -7.231  107.614 1.00 32.60  ? 155 ASP B N   1 
ATOM   3799  C CA  . ASP B 1 136 ? 25.749  -7.895  106.344 1.00 32.78  ? 155 ASP B CA  1 
ATOM   3800  C C   . ASP B 1 136 ? 24.466  -7.830  105.518 1.00 32.61  ? 155 ASP B C   1 
ATOM   3801  O O   . ASP B 1 136 ? 23.536  -8.623  105.704 1.00 34.10  ? 155 ASP B O   1 
ATOM   3802  C CB  . ASP B 1 136 ? 26.238  -9.320  106.548 1.00 34.23  ? 155 ASP B CB  1 
ATOM   3803  C CG  . ASP B 1 136 ? 26.648  -9.969  105.239 1.00 34.74  ? 155 ASP B CG  1 
ATOM   3804  O OD1 . ASP B 1 136 ? 26.494  -9.271  104.214 1.00 33.71  ? 155 ASP B OD1 1 
ATOM   3805  O OD2 . ASP B 1 136 ? 27.108  -11.150 105.218 1.00 36.39  ? 155 ASP B OD2 1 
ATOM   3806  N N   . LEU B 1 137 ? 24.399  -6.824  104.641 1.00 33.99  ? 156 LEU B N   1 
ATOM   3807  C CA  . LEU B 1 137 ? 23.202  -6.605  103.866 1.00 33.29  ? 156 LEU B CA  1 
ATOM   3808  C C   . LEU B 1 137 ? 22.997  -7.686  102.833 1.00 33.93  ? 156 LEU B C   1 
ATOM   3809  O O   . LEU B 1 137 ? 21.907  -7.763  102.257 1.00 33.75  ? 156 LEU B O   1 
ATOM   3810  C CB  . LEU B 1 137 ? 23.259  -5.253  103.153 1.00 32.17  ? 156 LEU B CB  1 
ATOM   3811  C CG  . LEU B 1 137 ? 23.455  -3.941  103.893 1.00 31.95  ? 156 LEU B CG  1 
ATOM   3812  C CD1 . LEU B 1 137 ? 23.221  -2.833  102.893 1.00 31.03  ? 156 LEU B CD1 1 
ATOM   3813  C CD2 . LEU B 1 137 ? 22.492  -3.762  104.977 1.00 32.10  ? 156 LEU B CD2 1 
ATOM   3814  N N   . SER B 1 138 ? 24.037  -8.469  102.529 1.00 30.73  ? 157 SER B N   1 
ATOM   3815  C CA  . SER B 1 138 ? 23.905  -9.607  101.607 1.00 31.42  ? 157 SER B CA  1 
ATOM   3816  C C   . SER B 1 138 ? 23.186  -10.814 102.222 1.00 32.77  ? 157 SER B C   1 
ATOM   3817  O O   . SER B 1 138 ? 22.911  -11.771 101.509 1.00 33.83  ? 157 SER B O   1 
ATOM   3818  C CB  . SER B 1 138 ? 25.285  -10.071 101.117 1.00 32.24  ? 157 SER B CB  1 
ATOM   3819  O OG  . SER B 1 138 ? 25.942  -10.775 102.135 1.00 33.33  ? 157 SER B OG  1 
ATOM   3820  N N   . ASN B 1 139 ? 22.862  -10.778 103.502 1.00 32.34  ? 158 ASN B N   1 
ATOM   3821  C CA  . ASN B 1 139 ? 22.207  -11.887 104.177 1.00 33.62  ? 158 ASN B CA  1 
ATOM   3822  C C   . ASN B 1 139 ? 20.702  -11.662 104.166 1.00 33.63  ? 158 ASN B C   1 
ATOM   3823  O O   . ASN B 1 139 ? 20.198  -10.753 104.845 1.00 33.18  ? 158 ASN B O   1 
ATOM   3824  C CB  . ASN B 1 139 ? 22.704  -12.023 105.611 1.00 34.48  ? 158 ASN B CB  1 
ATOM   3825  C CG  . ASN B 1 139 ? 22.096  -13.179 106.311 1.00 35.75  ? 158 ASN B CG  1 
ATOM   3826  O OD1 . ASN B 1 139 ? 20.881  -13.311 106.384 1.00 36.00  ? 158 ASN B OD1 1 
ATOM   3827  N ND2 . ASN B 1 139 ? 22.936  -14.046 106.835 1.00 36.98  ? 158 ASN B ND2 1 
ATOM   3828  N N   . ALA B 1 140 ? 19.976  -12.539 103.453 1.00 34.15  ? 159 ALA B N   1 
ATOM   3829  C CA  . ALA B 1 140 ? 18.548  -12.332 103.273 1.00 33.50  ? 159 ALA B CA  1 
ATOM   3830  C C   . ALA B 1 140 ? 17.771  -12.517 104.562 1.00 34.10  ? 159 ALA B C   1 
ATOM   3831  O O   . ALA B 1 140 ? 16.771  -11.819 104.767 1.00 33.71  ? 159 ALA B O   1 
ATOM   3832  C CB  . ALA B 1 140 ? 18.015  -13.279 102.210 1.00 34.16  ? 159 ALA B CB  1 
ATOM   3833  N N   . GLU B 1 141 ? 18.196  -13.437 105.439 1.00 34.55  ? 160 GLU B N   1 
ATOM   3834  C CA  . GLU B 1 141 ? 17.509  -13.615 106.723 1.00 35.23  ? 160 GLU B CA  1 
ATOM   3835  C C   . GLU B 1 141 ? 17.502  -12.321 107.509 1.00 34.30  ? 160 GLU B C   1 
ATOM   3836  O O   . GLU B 1 141 ? 16.492  -11.978 108.136 1.00 34.03  ? 160 GLU B O   1 
ATOM   3837  C CB  . GLU B 1 141 ? 18.176  -14.716 107.569 1.00 37.27  ? 160 GLU B CB  1 
ATOM   3838  C CG  . GLU B 1 141 ? 17.405  -16.021 107.610 1.00 39.92  ? 160 GLU B CG  1 
ATOM   3839  C CD  . GLU B 1 141 ? 18.145  -17.189 108.328 1.00 42.51  ? 160 GLU B CD  1 
ATOM   3840  O OE1 . GLU B 1 141 ? 18.920  -16.996 109.337 1.00 43.03  ? 160 GLU B OE1 1 
ATOM   3841  O OE2 . GLU B 1 141 ? 17.903  -18.342 107.882 1.00 44.15  ? 160 GLU B OE2 1 
ATOM   3842  N N   . PHE B 1 142 ? 18.648  -11.627 107.514 1.00 36.28  ? 161 PHE B N   1 
ATOM   3843  C CA  . PHE B 1 142 ? 18.793  -10.366 108.229 1.00 35.73  ? 161 PHE B CA  1 
ATOM   3844  C C   . PHE B 1 142 ? 17.924  -9.283  107.601 1.00 34.45  ? 161 PHE B C   1 
ATOM   3845  O O   . PHE B 1 142 ? 17.230  -8.524  108.299 1.00 34.39  ? 161 PHE B O   1 
ATOM   3846  C CB  . PHE B 1 142 ? 20.260  -9.907  108.212 1.00 35.47  ? 161 PHE B CB  1 
ATOM   3847  C CG  . PHE B 1 142 ? 20.402  -8.414  108.265 1.00 34.09  ? 161 PHE B CG  1 
ATOM   3848  C CD1 . PHE B 1 142 ? 20.215  -7.734  109.477 1.00 33.63  ? 161 PHE B CD1 1 
ATOM   3849  C CD2 . PHE B 1 142 ? 20.689  -7.670  107.119 1.00 33.23  ? 161 PHE B CD2 1 
ATOM   3850  C CE1 . PHE B 1 142 ? 20.322  -6.336  109.544 1.00 31.87  ? 161 PHE B CE1 1 
ATOM   3851  C CE2 . PHE B 1 142 ? 20.779  -6.254  107.178 1.00 31.18  ? 161 PHE B CE2 1 
ATOM   3852  C CZ  . PHE B 1 142 ? 20.592  -5.600  108.400 1.00 30.72  ? 161 PHE B CZ  1 
ATOM   3853  N N   . ARG B 1 143 ? 17.976  -9.183  106.266 1.00 34.87  ? 162 ARG B N   1 
ATOM   3854  C CA  . ARG B 1 143 ? 17.147  -8.225  105.548 1.00 33.58  ? 162 ARG B CA  1 
ATOM   3855  C C   . ARG B 1 143 ? 15.687  -8.417  105.912 1.00 34.02  ? 162 ARG B C   1 
ATOM   3856  O O   . ARG B 1 143 ? 14.968  -7.456  106.223 1.00 33.24  ? 162 ARG B O   1 
ATOM   3857  C CB  . ARG B 1 143 ? 17.367  -8.380  104.049 1.00 32.56  ? 162 ARG B CB  1 
ATOM   3858  C CG  . ARG B 1 143 ? 18.726  -7.926  103.608 1.00 32.17  ? 162 ARG B CG  1 
ATOM   3859  C CD  . ARG B 1 143 ? 18.700  -7.511  102.162 1.00 31.24  ? 162 ARG B CD  1 
ATOM   3860  N NE  . ARG B 1 143 ? 18.160  -8.580  101.328 1.00 32.19  ? 162 ARG B NE  1 
ATOM   3861  C CZ  . ARG B 1 143 ? 18.891  -9.522  100.742 1.00 32.92  ? 162 ARG B CZ  1 
ATOM   3862  N NH1 . ARG B 1 143 ? 20.213  -9.541  100.830 1.00 33.75  ? 162 ARG B NH1 1 
ATOM   3863  N NH2 . ARG B 1 143 ? 18.280  -10.472 100.061 1.00 34.59  ? 162 ARG B NH2 1 
ATOM   3864  N N   . ASN B 1 144 ? 15.235  -9.662  105.926 1.00 31.95  ? 163 ASN B N   1 
ATOM   3865  C CA  . ASN B 1 144 ? 13.862  -9.874  106.331 1.00 32.39  ? 163 ASN B CA  1 
ATOM   3866  C C   . ASN B 1 144 ? 13.626  -9.328  107.724 1.00 32.65  ? 163 ASN B C   1 
ATOM   3867  O O   . ASN B 1 144 ? 12.578  -8.732  108.001 1.00 32.49  ? 163 ASN B O   1 
ATOM   3868  C CB  . ASN B 1 144 ? 13.493  -11.346 106.297 1.00 33.85  ? 163 ASN B CB  1 
ATOM   3869  C CG  . ASN B 1 144 ? 12.045  -11.563 106.627 1.00 35.10  ? 163 ASN B CG  1 
ATOM   3870  O OD1 . ASN B 1 144 ? 11.187  -11.231 105.836 1.00 34.92  ? 163 ASN B OD1 1 
ATOM   3871  N ND2 . ASN B 1 144 ? 11.761  -12.094 107.799 1.00 36.59  ? 163 ASN B ND2 1 
ATOM   3872  N N   . TRP B 1 145 ? 14.580  -9.560  108.623 1.00 34.66  ? 164 TRP B N   1 
ATOM   3873  C CA  . TRP B 1 145 ? 14.426  -9.130  110.003 1.00 34.72  ? 164 TRP B CA  1 
ATOM   3874  C C   . TRP B 1 145 ? 14.485  -7.613  110.092 1.00 33.43  ? 164 TRP B C   1 
ATOM   3875  O O   . TRP B 1 145 ? 13.691  -6.986  110.807 1.00 33.38  ? 164 TRP B O   1 
ATOM   3876  C CB  . TRP B 1 145 ? 15.524  -9.765  110.848 1.00 35.72  ? 164 TRP B CB  1 
ATOM   3877  C CG  . TRP B 1 145 ? 15.663  -9.122  112.169 1.00 35.58  ? 164 TRP B CG  1 
ATOM   3878  C CD1 . TRP B 1 145 ? 14.993  -9.445  113.310 1.00 36.54  ? 164 TRP B CD1 1 
ATOM   3879  C CD2 . TRP B 1 145 ? 16.498  -8.030  112.488 1.00 34.31  ? 164 TRP B CD2 1 
ATOM   3880  N NE1 . TRP B 1 145 ? 15.368  -8.625  114.330 1.00 36.07  ? 164 TRP B NE1 1 
ATOM   3881  C CE2 . TRP B 1 145 ? 16.293  -7.736  113.853 1.00 34.87  ? 164 TRP B CE2 1 
ATOM   3882  C CE3 . TRP B 1 145 ? 17.423  -7.275  111.764 1.00 33.62  ? 164 TRP B CE3 1 
ATOM   3883  C CZ2 . TRP B 1 145 ? 16.967  -6.704  114.499 1.00 34.31  ? 164 TRP B CZ2 1 
ATOM   3884  C CZ3 . TRP B 1 145 ? 18.075  -6.240  112.405 1.00 32.56  ? 164 TRP B CZ3 1 
ATOM   3885  C CH2 . TRP B 1 145 ? 17.840  -5.968  113.745 1.00 33.08  ? 164 TRP B CH2 1 
ATOM   3886  N N   . TRP B 1 146 ? 15.415  -7.003  109.355 1.00 36.90  ? 165 TRP B N   1 
ATOM   3887  C CA  . TRP B 1 146 ? 15.567  -5.556  109.402 1.00 35.43  ? 165 TRP B CA  1 
ATOM   3888  C C   . TRP B 1 146 ? 14.344  -4.851  108.853 1.00 34.89  ? 165 TRP B C   1 
ATOM   3889  O O   . TRP B 1 146 ? 13.920  -3.832  109.409 1.00 34.27  ? 165 TRP B O   1 
ATOM   3890  C CB  . TRP B 1 146 ? 16.801  -5.154  108.609 1.00 34.54  ? 165 TRP B CB  1 
ATOM   3891  C CG  . TRP B 1 146 ? 17.161  -3.690  108.706 1.00 32.61  ? 165 TRP B CG  1 
ATOM   3892  C CD1 . TRP B 1 146 ? 18.024  -3.114  109.601 1.00 31.87  ? 165 TRP B CD1 1 
ATOM   3893  C CD2 . TRP B 1 146 ? 16.684  -2.631  107.872 1.00 31.23  ? 165 TRP B CD2 1 
ATOM   3894  N NE1 . TRP B 1 146 ? 18.108  -1.780  109.373 1.00 30.61  ? 165 TRP B NE1 1 
ATOM   3895  C CE2 . TRP B 1 146 ? 17.300  -1.445  108.320 1.00 29.98  ? 165 TRP B CE2 1 
ATOM   3896  C CE3 . TRP B 1 146 ? 15.789  -2.567  106.796 1.00 31.32  ? 165 TRP B CE3 1 
ATOM   3897  C CZ2 . TRP B 1 146 ? 17.043  -0.198  107.740 1.00 29.24  ? 165 TRP B CZ2 1 
ATOM   3898  C CZ3 . TRP B 1 146 ? 15.552  -1.350  106.208 1.00 30.02  ? 165 TRP B CZ3 1 
ATOM   3899  C CH2 . TRP B 1 146 ? 16.176  -0.179  106.677 1.00 29.12  ? 165 TRP B CH2 1 
ATOM   3900  N N   . THR B 1 147 ? 13.770  -5.367  107.740 1.00 32.92  ? 166 THR B N   1 
ATOM   3901  C CA  . THR B 1 147 ? 12.590  -4.739  107.166 1.00 32.85  ? 166 THR B CA  1 
ATOM   3902  C C   . THR B 1 147 ? 11.368  -4.967  108.041 1.00 33.66  ? 166 THR B C   1 
ATOM   3903  O O   . THR B 1 147 ? 10.492  -4.103  108.120 1.00 33.65  ? 166 THR B O   1 
ATOM   3904  C CB  . THR B 1 147 ? 12.323  -5.256  105.753 1.00 32.65  ? 166 THR B CB  1 
ATOM   3905  O OG1 . THR B 1 147 ? 12.356  -6.699  105.726 1.00 33.75  ? 166 THR B OG1 1 
ATOM   3906  C CG2 . THR B 1 147 ? 13.339  -4.657  104.749 1.00 31.36  ? 166 THR B CG2 1 
ATOM   3907  N N   . ASN B 1 148 ? 11.291  -6.101  108.735 1.00 32.16  ? 167 ASN B N   1 
ATOM   3908  C CA  . ASN B 1 148 ? 10.201  -6.281  109.689 1.00 33.44  ? 167 ASN B CA  1 
ATOM   3909  C C   . ASN B 1 148 ? 10.218  -5.214  110.780 1.00 33.06  ? 167 ASN B C   1 
ATOM   3910  O O   . ASN B 1 148 ? 9.166   -4.879  111.343 1.00 33.64  ? 167 ASN B O   1 
ATOM   3911  C CB  . ASN B 1 148 ? 10.283  -7.662  110.315 1.00 35.35  ? 167 ASN B CB  1 
ATOM   3912  C CG  . ASN B 1 148 ? 9.909   -8.762  109.343 1.00 36.74  ? 167 ASN B CG  1 
ATOM   3913  O OD1 . ASN B 1 148 ? 9.407   -8.512  108.223 1.00 36.28  ? 167 ASN B OD1 1 
ATOM   3914  N ND2 . ASN B 1 148 ? 10.170  -9.997  109.752 1.00 38.52  ? 167 ASN B ND2 1 
ATOM   3915  N N   . VAL B 1 149 ? 11.398  -4.693  111.113 1.00 35.44  ? 168 VAL B N   1 
ATOM   3916  C CA  . VAL B 1 149 ? 11.473  -3.691  112.164 1.00 34.92  ? 168 VAL B CA  1 
ATOM   3917  C C   . VAL B 1 149 ? 10.889  -2.390  111.649 1.00 33.90  ? 168 VAL B C   1 
ATOM   3918  O O   . VAL B 1 149 ? 9.986   -1.794  112.251 1.00 34.34  ? 168 VAL B O   1 
ATOM   3919  C CB  . VAL B 1 149 ? 12.932  -3.505  112.630 1.00 34.05  ? 168 VAL B CB  1 
ATOM   3920  C CG1 . VAL B 1 149 ? 13.070  -2.278  113.511 1.00 33.59  ? 168 VAL B CG1 1 
ATOM   3921  C CG2 . VAL B 1 149 ? 13.467  -4.740  113.369 1.00 35.40  ? 168 VAL B CG2 1 
ATOM   3922  N N   . ALA B 1 150 ? 11.384  -1.946  110.495 1.00 34.29  ? 169 ALA B N   1 
ATOM   3923  C CA  . ALA B 1 150 ? 10.744  -0.856  109.773 1.00 33.69  ? 169 ALA B CA  1 
ATOM   3924  C C   . ALA B 1 150 ? 9.242   -1.036  109.792 1.00 34.77  ? 169 ALA B C   1 
ATOM   3925  O O   . ALA B 1 150 ? 8.486   -0.125  110.131 1.00 34.96  ? 169 ALA B O   1 
ATOM   3926  C CB  . ALA B 1 150 ? 11.290  -0.833  108.346 1.00 33.20  ? 169 ALA B CB  1 
ATOM   3927  N N   . ALA B 1 151 ? 8.788   -2.239  109.452 1.00 35.07  ? 170 ALA B N   1 
ATOM   3928  C CA  . ALA B 1 151 ? 7.366   -2.425  109.214 1.00 35.89  ? 170 ALA B CA  1 
ATOM   3929  C C   . ALA B 1 151 ? 6.568   -2.333  110.498 1.00 36.58  ? 170 ALA B C   1 
ATOM   3930  O O   . ALA B 1 151 ? 5.467   -1.776  110.505 1.00 37.44  ? 170 ALA B O   1 
ATOM   3931  C CB  . ALA B 1 151 ? 7.143   -3.754  108.523 1.00 36.55  ? 170 ALA B CB  1 
ATOM   3932  N N   . LYS B 1 152 ? 7.101   -2.877  111.593 1.00 37.46  ? 171 LYS B N   1 
ATOM   3933  C CA  . LYS B 1 152 ? 6.423   -2.741  112.882 1.00 38.51  ? 171 LYS B CA  1 
ATOM   3934  C C   . LYS B 1 152 ? 6.293   -1.278  113.264 1.00 37.85  ? 171 LYS B C   1 
ATOM   3935  O O   . LYS B 1 152 ? 5.308   -0.874  113.890 1.00 39.09  ? 171 LYS B O   1 
ATOM   3936  C CB  . LYS B 1 152 ? 7.177   -3.520  113.960 1.00 39.65  ? 171 LYS B CB  1 
ATOM   3937  C CG  . LYS B 1 152 ? 6.504   -3.555  115.317 1.00 42.10  ? 171 LYS B CG  1 
ATOM   3938  C CD  . LYS B 1 152 ? 7.286   -4.431  116.315 1.00 43.24  ? 171 LYS B CD  1 
ATOM   3939  C CE  . LYS B 1 152 ? 6.348   -5.168  117.293 1.00 46.60  ? 171 LYS B CE  1 
ATOM   3940  N NZ  . LYS B 1 152 ? 7.020   -5.879  118.480 1.00 48.52  ? 171 LYS B NZ  1 
ATOM   3941  N N   . ALA B 1 153 ? 7.251   -0.467  112.844 1.00 37.95  ? 172 ALA B N   1 
ATOM   3942  C CA  . ALA B 1 153 ? 7.228   0.960   113.149 1.00 37.76  ? 172 ALA B CA  1 
ATOM   3943  C C   . ALA B 1 153 ? 6.227   1.734   112.293 1.00 37.93  ? 172 ALA B C   1 
ATOM   3944  O O   . ALA B 1 153 ? 5.482   2.577   112.817 1.00 38.64  ? 172 ALA B O   1 
ATOM   3945  C CB  . ALA B 1 153 ? 8.629   1.539   112.948 1.00 36.39  ? 172 ALA B CB  1 
ATOM   3946  N N   . VAL B 1 154 ? 6.198   1.511   110.979 1.00 37.91  ? 173 VAL B N   1 
ATOM   3947  C CA  . VAL B 1 154 ? 5.404   2.398   110.141 1.00 38.57  ? 173 VAL B CA  1 
ATOM   3948  C C   . VAL B 1 154 ? 4.059   1.814   109.777 1.00 39.91  ? 173 VAL B C   1 
ATOM   3949  O O   . VAL B 1 154 ? 3.141   2.599   109.475 1.00 40.88  ? 173 VAL B O   1 
ATOM   3950  C CB  . VAL B 1 154 ? 6.160   2.825   108.864 1.00 38.51  ? 173 VAL B CB  1 
ATOM   3951  C CG1 . VAL B 1 154 ? 7.649   2.969   109.187 1.00 36.79  ? 173 VAL B CG1 1 
ATOM   3952  C CG2 . VAL B 1 154 ? 5.941   1.873   107.817 1.00 39.44  ? 173 VAL B CG2 1 
ATOM   3953  N N   . VAL B 1 155 ? 3.883   0.506   109.844 1.00 39.51  ? 174 VAL B N   1 
ATOM   3954  C CA  . VAL B 1 155 ? 2.604   -0.082  109.482 1.00 40.99  ? 174 VAL B CA  1 
ATOM   3955  C C   . VAL B 1 155 ? 1.779   -0.160  110.753 1.00 42.17  ? 174 VAL B C   1 
ATOM   3956  O O   . VAL B 1 155 ? 0.786   0.559   110.904 1.00 43.66  ? 174 VAL B O   1 
ATOM   3957  C CB  . VAL B 1 155 ? 2.762   -1.474  108.834 1.00 41.18  ? 174 VAL B CB  1 
ATOM   3958  C CG1 . VAL B 1 155 ? 1.433   -2.122  108.686 1.00 42.59  ? 174 VAL B CG1 1 
ATOM   3959  C CG2 . VAL B 1 155 ? 3.500   -1.379  107.488 1.00 40.28  ? 174 VAL B CG2 1 
ATOM   3960  N N   . ASP B 1 156 ? 2.210   -1.038  111.668 1.00 42.11  ? 175 ASP B N   1 
ATOM   3961  C CA  . ASP B 1 156 ? 1.504   -1.271  112.928 1.00 43.82  ? 175 ASP B CA  1 
ATOM   3962  C C   . ASP B 1 156 ? 1.561   -0.036  113.812 1.00 43.51  ? 175 ASP B C   1 
ATOM   3963  O O   . ASP B 1 156 ? 0.605   0.260   114.533 1.00 45.40  ? 175 ASP B O   1 
ATOM   3964  C CB  . ASP B 1 156 ? 2.117   -2.491  113.638 1.00 44.95  ? 175 ASP B CB  1 
ATOM   3965  C CG  . ASP B 1 156 ? 2.259   -3.720  112.683 1.00 46.78  ? 175 ASP B CG  1 
ATOM   3966  O OD1 . ASP B 1 156 ? 1.429   -3.892  111.730 1.00 47.25  ? 175 ASP B OD1 1 
ATOM   3967  O OD2 . ASP B 1 156 ? 3.234   -4.504  112.865 1.00 48.21  ? 175 ASP B OD2 1 
ATOM   3968  N N   . GLY B 1 157 ? 2.655   0.713   113.740 1.00 41.83  ? 176 GLY B N   1 
ATOM   3969  C CA  . GLY B 1 157 ? 2.792   1.945   114.481 1.00 41.68  ? 176 GLY B CA  1 
ATOM   3970  C C   . GLY B 1 157 ? 2.220   3.160   113.770 1.00 41.64  ? 176 GLY B C   1 
ATOM   3971  O O   . GLY B 1 157 ? 1.574   3.077   112.724 1.00 42.13  ? 176 GLY B O   1 
ATOM   3972  N N   . THR B 1 158 ? 2.495   4.322   114.360 1.00 39.91  ? 177 THR B N   1 
ATOM   3973  C CA  . THR B 1 158 ? 1.948   5.601   113.914 1.00 40.51  ? 177 THR B CA  1 
ATOM   3974  C C   . THR B 1 158 ? 2.868   6.392   112.986 1.00 39.11  ? 177 THR B C   1 
ATOM   3975  O O   . THR B 1 158 ? 2.477   7.463   112.490 1.00 39.86  ? 177 THR B O   1 
ATOM   3976  C CB  . THR B 1 158 ? 1.612   6.465   115.121 1.00 41.92  ? 177 THR B CB  1 
ATOM   3977  O OG1 . THR B 1 158 ? 0.879   5.674   116.039 1.00 43.82  ? 177 THR B OG1 1 
ATOM   3978  C CG2 . THR B 1 158 ? 0.777   7.624   114.705 1.00 43.14  ? 177 THR B CG2 1 
ATOM   3979  N N   . CYS B 1 159 ? 4.070   5.903   112.737 1.00 40.40  ? 178 CYS B N   1 
ATOM   3980  C CA  . CYS B 1 159 ? 4.907   6.559   111.756 1.00 38.86  ? 178 CYS B CA  1 
ATOM   3981  C C   . CYS B 1 159 ? 4.300   6.421   110.360 1.00 39.14  ? 178 CYS B C   1 
ATOM   3982  O O   . CYS B 1 159 ? 3.371   5.640   110.123 1.00 40.29  ? 178 CYS B O   1 
ATOM   3983  C CB  . CYS B 1 159 ? 6.312   5.990   111.841 1.00 37.72  ? 178 CYS B CB  1 
ATOM   3984  S SG  . CYS B 1 159 ? 7.087   6.552   113.358 1.00 37.71  ? 178 CYS B SG  1 
ATOM   3985  N N   . ASP B 1 160 ? 4.833   7.245   109.445 1.00 35.45  ? 179 ASP B N   1 
ATOM   3986  C CA  . ASP B 1 160 ? 4.393   7.369   108.066 1.00 35.63  ? 179 ASP B CA  1 
ATOM   3987  C C   . ASP B 1 160 ? 5.476   6.950   107.089 1.00 34.55  ? 179 ASP B C   1 
ATOM   3988  O O   . ASP B 1 160 ? 5.284   7.026   105.869 1.00 35.24  ? 179 ASP B O   1 
ATOM   3989  C CB  . ASP B 1 160 ? 4.000   8.811   107.759 1.00 36.81  ? 179 ASP B CB  1 
ATOM   3990  C CG  . ASP B 1 160 ? 3.008   9.344   108.725 1.00 38.18  ? 179 ASP B CG  1 
ATOM   3991  O OD1 . ASP B 1 160 ? 1.876   8.846   108.711 1.00 39.81  ? 179 ASP B OD1 1 
ATOM   3992  O OD2 . ASP B 1 160 ? 3.316   10.273  109.484 1.00 38.46  ? 179 ASP B OD2 1 
ATOM   3993  N N   . GLY B 1 161 ? 6.621   6.557   107.584 1.00 34.06  ? 180 GLY B N   1 
ATOM   3994  C CA  . GLY B 1 161 ? 7.717   6.198   106.713 1.00 32.76  ? 180 GLY B CA  1 
ATOM   3995  C C   . GLY B 1 161 ? 8.952   6.005   107.557 1.00 31.32  ? 180 GLY B C   1 
ATOM   3996  O O   . GLY B 1 161 ? 8.922   6.154   108.781 1.00 31.61  ? 180 GLY B O   1 
ATOM   3997  N N   . VAL B 1 162 ? 10.044  5.687   106.863 1.00 31.78  ? 181 VAL B N   1 
ATOM   3998  C CA  . VAL B 1 162 ? 11.312  5.351   107.496 1.00 30.72  ? 181 VAL B CA  1 
ATOM   3999  C C   . VAL B 1 162 ? 12.454  6.107   106.831 1.00 29.88  ? 181 VAL B C   1 
ATOM   4000  O O   . VAL B 1 162 ? 12.402  6.485   105.656 1.00 30.22  ? 181 VAL B O   1 
ATOM   4001  C CB  . VAL B 1 162 ? 11.593  3.821   107.456 1.00 30.58  ? 181 VAL B CB  1 
ATOM   4002  C CG1 . VAL B 1 162 ? 11.506  3.336   106.022 1.00 30.87  ? 181 VAL B CG1 1 
ATOM   4003  C CG2 . VAL B 1 162 ? 12.967  3.498   108.088 1.00 29.98  ? 181 VAL B CG2 1 
ATOM   4004  N N   . PHE B 1 163 ? 13.494  6.317   107.620 1.00 30.33  ? 182 PHE B N   1 
ATOM   4005  C CA  . PHE B 1 163 ? 14.692  7.027   107.224 1.00 29.99  ? 182 PHE B CA  1 
ATOM   4006  C C   . PHE B 1 163 ? 15.848  6.038   107.250 1.00 29.57  ? 182 PHE B C   1 
ATOM   4007  O O   . PHE B 1 163 ? 16.186  5.512   108.309 1.00 29.88  ? 182 PHE B O   1 
ATOM   4008  C CB  . PHE B 1 163 ? 14.954  8.205   108.173 1.00 30.70  ? 182 PHE B CB  1 
ATOM   4009  C CG  . PHE B 1 163 ? 16.127  9.003   107.783 1.00 31.25  ? 182 PHE B CG  1 
ATOM   4010  C CD1 . PHE B 1 163 ? 17.381  8.702   108.269 1.00 31.24  ? 182 PHE B CD1 1 
ATOM   4011  C CD2 . PHE B 1 163 ? 15.986  10.068  106.919 1.00 32.43  ? 182 PHE B CD2 1 
ATOM   4012  C CE1 . PHE B 1 163 ? 18.488  9.434   107.902 1.00 32.16  ? 182 PHE B CE1 1 
ATOM   4013  C CE2 . PHE B 1 163 ? 17.102  10.852  106.551 1.00 33.65  ? 182 PHE B CE2 1 
ATOM   4014  C CZ  . PHE B 1 163 ? 18.362  10.500  107.036 1.00 33.36  ? 182 PHE B CZ  1 
ATOM   4015  N N   . MET B 1 164 ? 16.427  5.778   106.101 1.00 30.45  ? 183 MET B N   1 
ATOM   4016  C CA  . MET B 1 164 ? 17.484  4.794   105.934 1.00 30.33  ? 183 MET B CA  1 
ATOM   4017  C C   . MET B 1 164 ? 18.768  5.591   105.905 1.00 30.43  ? 183 MET B C   1 
ATOM   4018  O O   . MET B 1 164 ? 19.105  6.226   104.907 1.00 31.25  ? 183 MET B O   1 
ATOM   4019  C CB  . MET B 1 164 ? 17.286  3.985   104.668 1.00 29.87  ? 183 MET B CB  1 
ATOM   4020  C CG  . MET B 1 164 ? 16.230  2.915   104.860 1.00 30.65  ? 183 MET B CG  1 
ATOM   4021  S SD  . MET B 1 164 ? 15.263  2.451   103.342 1.00 31.57  ? 183 MET B SD  1 
ATOM   4022  C CE  . MET B 1 164 ? 16.314  1.067   102.866 1.00 31.34  ? 183 MET B CE  1 
ATOM   4023  N N   . ASP B 1 165 ? 19.498  5.557   107.012 1.00 30.06  ? 184 ASP B N   1 
ATOM   4024  C CA  . ASP B 1 165 ? 20.773  6.242   107.069 1.00 31.07  ? 184 ASP B CA  1 
ATOM   4025  C C   . ASP B 1 165 ? 21.897  5.364   106.535 1.00 31.56  ? 184 ASP B C   1 
ATOM   4026  O O   . ASP B 1 165 ? 21.760  4.146   106.371 1.00 31.28  ? 184 ASP B O   1 
ATOM   4027  C CB  . ASP B 1 165 ? 21.047  6.664   108.506 1.00 31.65  ? 184 ASP B CB  1 
ATOM   4028  C CG  . ASP B 1 165 ? 21.968  7.820   108.594 1.00 33.12  ? 184 ASP B CG  1 
ATOM   4029  O OD1 . ASP B 1 165 ? 22.359  8.305   107.518 1.00 34.27  ? 184 ASP B OD1 1 
ATOM   4030  O OD2 . ASP B 1 165 ? 22.320  8.211   109.729 1.00 33.88  ? 184 ASP B OD2 1 
ATOM   4031  N N   . ALA B 1 166 ? 22.993  6.029   106.178 1.00 31.99  ? 185 ALA B N   1 
ATOM   4032  C CA  . ALA B 1 166 ? 24.325  5.445   106.062 1.00 32.85  ? 185 ALA B CA  1 
ATOM   4033  C C   . ALA B 1 166 ? 24.664  4.825   104.721 1.00 32.77  ? 185 ALA B C   1 
ATOM   4034  O O   . ALA B 1 166 ? 25.645  4.081   104.630 1.00 33.53  ? 185 ALA B O   1 
ATOM   4035  C CB  . ALA B 1 166 ? 24.550  4.384   107.150 1.00 32.65  ? 185 ALA B CB  1 
ATOM   4036  N N   . PHE B 1 167 ? 23.950  5.172   103.652 1.00 31.96  ? 186 PHE B N   1 
ATOM   4037  C CA  . PHE B 1 167 ? 24.324  4.597   102.366 1.00 32.03  ? 186 PHE B CA  1 
ATOM   4038  C C   . PHE B 1 167 ? 25.767  4.887   101.959 1.00 33.67  ? 186 PHE B C   1 
ATOM   4039  O O   . PHE B 1 167 ? 26.434  3.955   101.493 1.00 33.93  ? 186 PHE B O   1 
ATOM   4040  C CB  . PHE B 1 167 ? 23.393  5.069   101.264 1.00 31.88  ? 186 PHE B CB  1 
ATOM   4041  C CG  . PHE B 1 167 ? 22.042  4.502   101.339 1.00 30.54  ? 186 PHE B CG  1 
ATOM   4042  C CD1 . PHE B 1 167 ? 21.509  4.115   102.532 1.00 29.87  ? 186 PHE B CD1 1 
ATOM   4043  C CD2 . PHE B 1 167 ? 21.287  4.384   100.213 1.00 30.65  ? 186 PHE B CD2 1 
ATOM   4044  C CE1 . PHE B 1 167 ? 20.246  3.612   102.612 1.00 28.86  ? 186 PHE B CE1 1 
ATOM   4045  C CE2 . PHE B 1 167 ? 20.030  3.893   100.291 1.00 29.82  ? 186 PHE B CE2 1 
ATOM   4046  C CZ  . PHE B 1 167 ? 19.505  3.517   101.499 1.00 29.05  ? 186 PHE B CZ  1 
ATOM   4047  N N   . PRO B 1 168 ? 26.307  6.103   102.095 1.00 32.16  ? 187 PRO B N   1 
ATOM   4048  C CA  . PRO B 1 168 ? 27.724  6.330   101.731 1.00 33.76  ? 187 PRO B CA  1 
ATOM   4049  C C   . PRO B 1 168 ? 28.698  5.530   102.561 1.00 33.93  ? 187 PRO B C   1 
ATOM   4050  O O   . PRO B 1 168 ? 29.851  5.291   102.139 1.00 34.93  ? 187 PRO B O   1 
ATOM   4051  C CB  . PRO B 1 168 ? 27.918  7.834   101.976 1.00 35.34  ? 187 PRO B CB  1 
ATOM   4052  C CG  . PRO B 1 168 ? 26.521  8.366   101.943 1.00 34.78  ? 187 PRO B CG  1 
ATOM   4053  C CD  . PRO B 1 168 ? 25.640  7.345   102.537 1.00 32.90  ? 187 PRO B CD  1 
ATOM   4054  N N   . GLN B 1 169 ? 28.303  5.136   103.762 1.00 36.20  ? 188 GLN B N   1 
ATOM   4055  C CA  . GLN B 1 169 ? 29.173  4.281   104.553 1.00 35.79  ? 188 GLN B CA  1 
ATOM   4056  C C   . GLN B 1 169 ? 29.251  2.876   103.950 1.00 35.23  ? 188 GLN B C   1 
ATOM   4057  O O   . GLN B 1 169 ? 30.328  2.258   103.950 1.00 35.58  ? 188 GLN B O   1 
ATOM   4058  C CB  . GLN B 1 169 ? 28.669  4.251   105.996 1.00 35.29  ? 188 GLN B CB  1 
ATOM   4059  C CG  . GLN B 1 169 ? 28.826  5.580   106.752 1.00 35.90  ? 188 GLN B CG  1 
ATOM   4060  C CD  . GLN B 1 169 ? 28.290  5.468   108.188 1.00 35.43  ? 188 GLN B CD  1 
ATOM   4061  O OE1 . GLN B 1 169 ? 27.513  6.325   108.640 1.00 35.41  ? 188 GLN B OE1 1 
ATOM   4062  N NE2 . GLN B 1 169 ? 28.704  4.389   108.928 1.00 35.80  ? 188 GLN B NE2 1 
ATOM   4063  N N   . ILE B 1 170 ? 28.119  2.381   103.403 1.00 33.16  ? 189 ILE B N   1 
ATOM   4064  C CA  . ILE B 1 170 ? 28.059  1.042   102.815 1.00 32.61  ? 189 ILE B CA  1 
ATOM   4065  C C   . ILE B 1 170 ? 28.870  0.993   101.536 1.00 33.10  ? 189 ILE B C   1 
ATOM   4066  O O   . ILE B 1 170 ? 29.572  0.014   101.258 1.00 33.43  ? 189 ILE B O   1 
ATOM   4067  C CB  . ILE B 1 170 ? 26.595  0.638   102.555 1.00 31.54  ? 189 ILE B CB  1 
ATOM   4068  C CG1 . ILE B 1 170 ? 25.828  0.594   103.872 1.00 31.31  ? 189 ILE B CG1 1 
ATOM   4069  C CG2 . ILE B 1 170 ? 26.493  -0.686  101.840 1.00 31.49  ? 189 ILE B CG2 1 
ATOM   4070  C CD1 . ILE B 1 170 ? 24.345  0.600   103.717 1.00 30.27  ? 189 ILE B CD1 1 
ATOM   4071  N N   . ALA B 1 171 ? 28.806  2.061   100.747 1.00 33.15  ? 190 ALA B N   1 
ATOM   4072  C CA  . ALA B 1 171 ? 29.431  2.084   99.430  1.00 34.13  ? 190 ALA B CA  1 
ATOM   4073  C C   . ALA B 1 171 ? 30.904  2.435   99.467  1.00 35.22  ? 190 ALA B C   1 
ATOM   4074  O O   . ALA B 1 171 ? 31.569  2.383   98.430  1.00 36.33  ? 190 ALA B O   1 
ATOM   4075  C CB  . ALA B 1 171 ? 28.716  3.108   98.555  1.00 34.65  ? 190 ALA B CB  1 
ATOM   4076  N N   . SER B 1 172 ? 31.409  2.826   100.621 1.00 34.71  ? 191 SER B N   1 
ATOM   4077  C CA  . SER B 1 172 ? 32.800  3.229   100.775 1.00 35.79  ? 191 SER B CA  1 
ATOM   4078  C C   . SER B 1 172 ? 33.771  2.182   100.258 1.00 36.31  ? 191 SER B C   1 
ATOM   4079  O O   . SER B 1 172 ? 33.808  1.053   100.749 1.00 35.23  ? 191 SER B O   1 
ATOM   4080  C CB  . SER B 1 172 ? 33.059  3.487   102.250 1.00 36.22  ? 191 SER B CB  1 
ATOM   4081  O OG  . SER B 1 172 ? 34.415  3.731   102.418 1.00 37.84  ? 191 SER B OG  1 
ATOM   4082  N N   . GLN B 1 173 ? 34.565  2.569   99.267  1.00 35.23  ? 192 GLN B N   1 
ATOM   4083  C CA  . GLN B 1 173 ? 35.548  1.663   98.687  1.00 36.10  ? 192 GLN B CA  1 
ATOM   4084  C C   . GLN B 1 173 ? 36.468  1.018   99.724  1.00 36.25  ? 192 GLN B C   1 
ATOM   4085  O O   . GLN B 1 173 ? 36.881  -0.150  99.563  1.00 36.43  ? 192 GLN B O   1 
ATOM   4086  C CB  . GLN B 1 173 ? 36.334  2.444   97.636  1.00 37.79  ? 192 GLN B CB  1 
ATOM   4087  C CG  . GLN B 1 173 ? 35.423  2.878   96.506  1.00 38.34  ? 192 GLN B CG  1 
ATOM   4088  C CD  . GLN B 1 173 ? 34.965  1.689   95.673  1.00 38.05  ? 192 GLN B CD  1 
ATOM   4089  O OE1 . GLN B 1 173 ? 35.793  0.943   95.160  1.00 38.76  ? 192 GLN B OE1 1 
ATOM   4090  N NE2 . GLN B 1 173 ? 33.655  1.508   95.536  1.00 37.43  ? 192 GLN B NE2 1 
ATOM   4091  N N   . ALA B 1 174 ? 36.752  1.727   100.816 1.00 38.61  ? 193 ALA B N   1 
ATOM   4092  C CA  . ALA B 1 174 ? 37.610  1.158   101.844 1.00 38.46  ? 193 ALA B CA  1 
ATOM   4093  C C   . ALA B 1 174 ? 37.076  -0.174  102.355 1.00 37.15  ? 193 ALA B C   1 
ATOM   4094  O O   . ALA B 1 174 ? 37.857  -1.002  102.848 1.00 37.56  ? 193 ALA B O   1 
ATOM   4095  C CB  . ALA B 1 174 ? 37.772  2.138   103.000 1.00 39.00  ? 193 ALA B CB  1 
ATOM   4096  N N   . ASN B 1 175 ? 35.749  -0.402  102.259 1.00 36.87  ? 194 ASN B N   1 
ATOM   4097  C CA  . ASN B 1 175 ? 35.162  -1.655  102.726 1.00 36.04  ? 194 ASN B CA  1 
ATOM   4098  C C   . ASN B 1 175 ? 35.577  -2.853  101.886 1.00 36.50  ? 194 ASN B C   1 
ATOM   4099  O O   . ASN B 1 175 ? 35.403  -3.994  102.312 1.00 36.66  ? 194 ASN B O   1 
ATOM   4100  C CB  . ASN B 1 175 ? 33.649  -1.596  102.705 1.00 34.98  ? 194 ASN B CB  1 
ATOM   4101  C CG  . ASN B 1 175 ? 33.089  -0.685  103.750 1.00 34.74  ? 194 ASN B CG  1 
ATOM   4102  O OD1 . ASN B 1 175 ? 33.654  -0.538  104.816 1.00 35.02  ? 194 ASN B OD1 1 
ATOM   4103  N ND2 . ASN B 1 175 ? 31.941  -0.099  103.464 1.00 34.36  ? 194 ASN B ND2 1 
ATOM   4104  N N   . ARG B 1 176 ? 36.083  -2.613  100.688 1.00 35.44  ? 195 ARG B N   1 
ATOM   4105  C CA  . ARG B 1 176 ? 36.651  -3.685  99.903  1.00 36.23  ? 195 ARG B CA  1 
ATOM   4106  C C   . ARG B 1 176 ? 37.893  -4.228  100.559 1.00 37.23  ? 195 ARG B C   1 
ATOM   4107  O O   . ARG B 1 176 ? 38.170  -5.421  100.442 1.00 38.16  ? 195 ARG B O   1 
ATOM   4108  C CB  . ARG B 1 176 ? 36.989  -3.190  98.504  1.00 37.25  ? 195 ARG B CB  1 
ATOM   4109  C CG  . ARG B 1 176 ? 35.791  -2.809  97.654  1.00 36.88  ? 195 ARG B CG  1 
ATOM   4110  C CD  . ARG B 1 176 ? 36.310  -2.282  96.333  1.00 38.32  ? 195 ARG B CD  1 
ATOM   4111  N NE  . ARG B 1 176 ? 35.292  -1.989  95.322  1.00 38.42  ? 195 ARG B NE  1 
ATOM   4112  C CZ  . ARG B 1 176 ? 34.737  -2.878  94.495  1.00 38.34  ? 195 ARG B CZ  1 
ATOM   4113  N NH1 . ARG B 1 176 ? 34.950  -4.178  94.608  1.00 38.35  ? 195 ARG B NH1 1 
ATOM   4114  N NH2 . ARG B 1 176 ? 33.957  -2.447  93.520  1.00 38.15  ? 195 ARG B NH2 1 
ATOM   4115  N N   . LYS B 1 177 ? 38.669  -3.376  101.245 1.00 38.53  ? 196 LYS B N   1 
ATOM   4116  C CA  . LYS B 1 177 ? 39.836  -3.884  101.976 1.00 39.83  ? 196 LYS B CA  1 
ATOM   4117  C C   . LYS B 1 177 ? 39.389  -4.789  103.118 1.00 38.80  ? 196 LYS B C   1 
ATOM   4118  O O   . LYS B 1 177 ? 40.034  -5.791  103.406 1.00 39.41  ? 196 LYS B O   1 
ATOM   4119  C CB  . LYS B 1 177 ? 40.716  -2.742  102.475 1.00 41.86  ? 196 LYS B CB  1 
ATOM   4120  N N   . LEU B 1 178 ? 38.240  -4.536  103.699 1.00 38.80  ? 197 LEU B N   1 
ATOM   4121  C CA  . LEU B 1 178 ? 37.753  -5.354  104.793 1.00 38.73  ? 197 LEU B CA  1 
ATOM   4122  C C   . LEU B 1 178 ? 36.979  -6.596  104.384 1.00 38.49  ? 197 LEU B C   1 
ATOM   4123  O O   . LEU B 1 178 ? 36.999  -7.589  105.124 1.00 38.95  ? 197 LEU B O   1 
ATOM   4124  C CB  . LEU B 1 178 ? 36.836  -4.495  105.670 1.00 38.73  ? 197 LEU B CB  1 
ATOM   4125  C CG  . LEU B 1 178 ? 37.541  -3.360  106.430 1.00 39.96  ? 197 LEU B CG  1 
ATOM   4126  C CD1 . LEU B 1 178 ? 36.441  -2.482  106.989 1.00 39.62  ? 197 LEU B CD1 1 
ATOM   4127  C CD2 . LEU B 1 178 ? 38.442  -3.923  107.500 1.00 41.37  ? 197 LEU B CD2 1 
ATOM   4128  N N   . TRP B 1 179 ? 36.259  -6.554  103.261 1.00 37.79  ? 198 TRP B N   1 
ATOM   4129  C CA  . TRP B 1 179 ? 35.397  -7.647  102.865 1.00 37.79  ? 198 TRP B CA  1 
ATOM   4130  C C   . TRP B 1 179 ? 35.874  -8.401  101.631 1.00 38.40  ? 198 TRP B C   1 
ATOM   4131  O O   . TRP B 1 179 ? 35.395  -9.515  101.369 1.00 39.30  ? 198 TRP B O   1 
ATOM   4132  C CB  . TRP B 1 179 ? 33.998  -7.124  102.554 1.00 36.75  ? 198 TRP B CB  1 
ATOM   4133  C CG  . TRP B 1 179 ? 33.323  -6.333  103.600 1.00 35.91  ? 198 TRP B CG  1 
ATOM   4134  C CD1 . TRP B 1 179 ? 33.453  -6.459  104.937 1.00 36.14  ? 198 TRP B CD1 1 
ATOM   4135  C CD2 . TRP B 1 179 ? 32.370  -5.290  103.382 1.00 35.03  ? 198 TRP B CD2 1 
ATOM   4136  N NE1 . TRP B 1 179 ? 32.639  -5.562  105.582 1.00 35.52  ? 198 TRP B NE1 1 
ATOM   4137  C CE2 . TRP B 1 179 ? 31.970  -4.818  104.640 1.00 34.89  ? 198 TRP B CE2 1 
ATOM   4138  C CE3 . TRP B 1 179 ? 31.827  -4.701  102.247 1.00 34.55  ? 198 TRP B CE3 1 
ATOM   4139  C CZ2 . TRP B 1 179 ? 31.035  -3.792  104.790 1.00 34.14  ? 198 TRP B CZ2 1 
ATOM   4140  C CZ3 . TRP B 1 179 ? 30.909  -3.672  102.408 1.00 33.97  ? 198 TRP B CZ3 1 
ATOM   4141  C CH2 . TRP B 1 179 ? 30.516  -3.254  103.663 1.00 33.85  ? 198 TRP B CH2 1 
ATOM   4142  N N   . GLY B 1 180 ? 36.792  -7.836  100.867 1.00 36.86  ? 199 GLY B N   1 
ATOM   4143  C CA  . GLY B 1 180 ? 37.091  -8.366  99.562  1.00 37.82  ? 199 GLY B CA  1 
ATOM   4144  C C   . GLY B 1 180 ? 35.979  -8.048  98.578  1.00 37.73  ? 199 GLY B C   1 
ATOM   4145  O O   . GLY B 1 180 ? 34.849  -7.756  98.942  1.00 36.76  ? 199 GLY B O   1 
ATOM   4146  N N   . ASP B 1 181 ? 36.328  -8.118  97.295  1.00 37.60  ? 200 ASP B N   1 
ATOM   4147  C CA  . ASP B 1 181 ? 35.477  -7.566  96.255  1.00 37.17  ? 200 ASP B CA  1 
ATOM   4148  C C   . ASP B 1 181 ? 34.163  -8.322  96.147  1.00 37.38  ? 200 ASP B C   1 
ATOM   4149  O O   . ASP B 1 181 ? 33.101  -7.721  95.918  1.00 35.98  ? 200 ASP B O   1 
ATOM   4150  C CB  . ASP B 1 181 ? 36.217  -7.618  94.924  1.00 39.18  ? 200 ASP B CB  1 
ATOM   4151  C CG  . ASP B 1 181 ? 37.295  -6.575  94.810  1.00 39.92  ? 200 ASP B CG  1 
ATOM   4152  O OD1 . ASP B 1 181 ? 37.151  -5.470  95.405  1.00 38.49  ? 200 ASP B OD1 1 
ATOM   4153  O OD2 . ASP B 1 181 ? 38.288  -6.879  94.104  1.00 42.64  ? 200 ASP B OD2 1 
ATOM   4154  N N   . GLU B 1 182 ? 34.223  -9.644  96.264  1.00 36.61  ? 201 GLU B N   1 
ATOM   4155  C CA  . GLU B 1 182 ? 33.039  -10.485 96.150  1.00 37.57  ? 201 GLU B CA  1 
ATOM   4156  C C   . GLU B 1 182 ? 31.990  -10.066 97.165  1.00 35.24  ? 201 GLU B C   1 
ATOM   4157  O O   . GLU B 1 182 ? 30.870  -9.708  96.809  1.00 34.31  ? 201 GLU B O   1 
ATOM   4158  C CB  . GLU B 1 182 ? 33.494  -11.928 96.354  1.00 41.02  ? 201 GLU B CB  1 
ATOM   4159  C CG  . GLU B 1 182 ? 32.665  -13.040 95.781  1.00 43.81  ? 201 GLU B CG  1 
ATOM   4160  C CD  . GLU B 1 182 ? 33.445  -14.369 95.784  1.00 47.12  ? 201 GLU B CD  1 
ATOM   4161  O OE1 . GLU B 1 182 ? 34.560  -14.433 95.183  1.00 48.08  ? 201 GLU B OE1 1 
ATOM   4162  O OE2 . GLU B 1 182 ? 32.962  -15.336 96.419  1.00 48.81  ? 201 GLU B OE2 1 
ATOM   4163  N N   . LYS B 1 183 ? 32.355  -10.042 98.436  1.00 36.22  ? 202 LYS B N   1 
ATOM   4164  C CA  . LYS B 1 183 ? 31.393  -9.719  99.491  1.00 34.29  ? 202 LYS B CA  1 
ATOM   4165  C C   . LYS B 1 183 ? 30.974  -8.249  99.446  1.00 31.91  ? 202 LYS B C   1 
ATOM   4166  O O   . LYS B 1 183 ? 29.869  -7.895  99.880  1.00 30.71  ? 202 LYS B O   1 
ATOM   4167  C CB  . LYS B 1 183 ? 32.037  -10.136 100.814 1.00 34.63  ? 202 LYS B CB  1 
ATOM   4168  C CG  . LYS B 1 183 ? 31.398  -9.670  102.063 1.00 33.37  ? 202 LYS B CG  1 
ATOM   4169  C CD  . LYS B 1 183 ? 30.029  -10.238 102.226 1.00 34.05  ? 202 LYS B CD  1 
ATOM   4170  C CE  . LYS B 1 183 ? 30.030  -11.379 103.139 1.00 35.63  ? 202 LYS B CE  1 
ATOM   4171  N NZ  . LYS B 1 183 ? 28.649  -11.866 103.207 1.00 35.30  ? 202 LYS B NZ  1 
ATOM   4172  N N   . PHE B 1 184 ? 31.822  -7.392  98.903  1.00 36.60  ? 203 PHE B N   1 
ATOM   4173  C CA  . PHE B 1 184 ? 31.460  -5.994  98.735  1.00 34.83  ? 203 PHE B CA  1 
ATOM   4174  C C   . PHE B 1 184 ? 30.362  -5.846  97.685  1.00 34.98  ? 203 PHE B C   1 
ATOM   4175  O O   . PHE B 1 184 ? 29.383  -5.104  97.887  1.00 33.33  ? 203 PHE B O   1 
ATOM   4176  C CB  . PHE B 1 184 ? 32.714  -5.189  98.351  1.00 35.26  ? 203 PHE B CB  1 
ATOM   4177  C CG  . PHE B 1 184 ? 32.451  -3.756  98.038  1.00 33.50  ? 203 PHE B CG  1 
ATOM   4178  C CD1 . PHE B 1 184 ? 32.512  -2.801  99.040  1.00 32.26  ? 203 PHE B CD1 1 
ATOM   4179  C CD2 . PHE B 1 184 ? 32.161  -3.363  96.739  1.00 34.12  ? 203 PHE B CD2 1 
ATOM   4180  C CE1 . PHE B 1 184 ? 32.272  -1.432  98.765  1.00 31.50  ? 203 PHE B CE1 1 
ATOM   4181  C CE2 . PHE B 1 184 ? 31.908  -2.009  96.441  1.00 33.11  ? 203 PHE B CE2 1 
ATOM   4182  C CZ  . PHE B 1 184 ? 31.967  -1.036  97.462  1.00 32.03  ? 203 PHE B CZ  1 
ATOM   4183  N N   . GLU B 1 185 ? 30.515  -6.537  96.536  1.00 33.49  ? 204 GLU B N   1 
ATOM   4184  C CA  . GLU B 1 185 ? 29.512  -6.421  95.478  1.00 33.77  ? 204 GLU B CA  1 
ATOM   4185  C C   . GLU B 1 185 ? 28.192  -6.997  95.930  1.00 33.37  ? 204 GLU B C   1 
ATOM   4186  O O   . GLU B 1 185 ? 27.125  -6.469  95.590  1.00 32.69  ? 204 GLU B O   1 
ATOM   4187  C CB  . GLU B 1 185 ? 29.987  -7.114  94.208  1.00 36.41  ? 204 GLU B CB  1 
ATOM   4188  C CG  . GLU B 1 185 ? 31.304  -6.582  93.758  1.00 37.49  ? 204 GLU B CG  1 
ATOM   4189  C CD  . GLU B 1 185 ? 31.557  -6.774  92.294  1.00 39.27  ? 204 GLU B CD  1 
ATOM   4190  O OE1 . GLU B 1 185 ? 31.220  -7.858  91.757  1.00 40.73  ? 204 GLU B OE1 1 
ATOM   4191  O OE2 . GLU B 1 185 ? 32.122  -5.827  91.680  1.00 39.72  ? 204 GLU B OE2 1 
ATOM   4192  N N   . ALA B 1 186 ? 28.266  -8.047  96.731  1.00 30.95  ? 205 ALA B N   1 
ATOM   4193  C CA  . ALA B 1 186 ? 27.084  -8.667  97.292  1.00 31.28  ? 205 ALA B CA  1 
ATOM   4194  C C   . ALA B 1 186 ? 26.409  -7.744  98.282  1.00 29.30  ? 205 ALA B C   1 
ATOM   4195  O O   . ALA B 1 186 ? 25.190  -7.754  98.391  1.00 29.30  ? 205 ALA B O   1 
ATOM   4196  C CB  . ALA B 1 186 ? 27.462  -10.006 97.969  1.00 32.75  ? 205 ALA B CB  1 
ATOM   4197  N N   . ILE B 1 187 ? 27.174  -6.968  99.055  1.00 33.78  ? 206 ILE B N   1 
ATOM   4198  C CA  . ILE B 1 187 ? 26.532  -6.095  100.038 1.00 31.39  ? 206 ILE B CA  1 
ATOM   4199  C C   . ILE B 1 187 ? 25.928  -4.885  99.353  1.00 30.22  ? 206 ILE B C   1 
ATOM   4200  O O   . ILE B 1 187 ? 24.845  -4.439  99.722  1.00 29.21  ? 206 ILE B O   1 
ATOM   4201  C CB  . ILE B 1 187 ? 27.516  -5.696  101.155 1.00 30.44  ? 206 ILE B CB  1 
ATOM   4202  C CG1 . ILE B 1 187 ? 27.745  -6.903  102.104 1.00 31.46  ? 206 ILE B CG1 1 
ATOM   4203  C CG2 . ILE B 1 187 ? 26.993  -4.517  101.969 1.00 28.10  ? 206 ILE B CG2 1 
ATOM   4204  C CD1 . ILE B 1 187 ? 28.664  -6.643  103.253 1.00 30.97  ? 206 ILE B CD1 1 
ATOM   4205  N N   . GLN B 1 188 ? 26.590  -4.346  98.335  1.00 31.07  ? 207 GLN B N   1 
ATOM   4206  C CA  . GLN B 1 188 ? 25.965  -3.274  97.560  1.00 30.14  ? 207 GLN B CA  1 
ATOM   4207  C C   . GLN B 1 188 ? 24.639  -3.747  96.987  1.00 31.24  ? 207 GLN B C   1 
ATOM   4208  O O   . GLN B 1 188 ? 23.612  -3.062  97.107  1.00 30.46  ? 207 GLN B O   1 
ATOM   4209  C CB  . GLN B 1 188 ? 26.872  -2.808  96.429  1.00 30.50  ? 207 GLN B CB  1 
ATOM   4210  C CG  . GLN B 1 188 ? 28.241  -2.344  96.865  1.00 30.19  ? 207 GLN B CG  1 
ATOM   4211  C CD  . GLN B 1 188 ? 28.233  -1.583  98.171  1.00 28.95  ? 207 GLN B CD  1 
ATOM   4212  O OE1 . GLN B 1 188 ? 27.384  -0.724  98.393  1.00 28.12  ? 207 GLN B OE1 1 
ATOM   4213  N NE2 . GLN B 1 188 ? 29.174  -1.888  99.041  1.00 29.19  ? 207 GLN B NE2 1 
ATOM   4214  N N   . GLN B 1 189 ? 24.635  -4.938  96.369  1.00 29.11  ? 208 GLN B N   1 
ATOM   4215  C CA  . GLN B 1 189 ? 23.380  -5.462  95.819  1.00 30.17  ? 208 GLN B CA  1 
ATOM   4216  C C   . GLN B 1 189 ? 22.329  -5.690  96.901  1.00 30.01  ? 208 GLN B C   1 
ATOM   4217  O O   . GLN B 1 189 ? 21.140  -5.553  96.633  1.00 30.27  ? 208 GLN B O   1 
ATOM   4218  C CB  . GLN B 1 189 ? 23.625  -6.761  95.063  1.00 32.56  ? 208 GLN B CB  1 
ATOM   4219  C CG  . GLN B 1 189 ? 22.353  -7.334  94.397  1.00 34.24  ? 208 GLN B CG  1 
ATOM   4220  C CD  . GLN B 1 189 ? 21.748  -6.409  93.348  1.00 34.10  ? 208 GLN B CD  1 
ATOM   4221  O OE1 . GLN B 1 189 ? 22.453  -5.880  92.459  1.00 34.84  ? 208 GLN B OE1 1 
ATOM   4222  N NE2 . GLN B 1 189 ? 20.427  -6.217  93.439  1.00 34.16  ? 208 GLN B NE2 1 
ATOM   4223  N N   . GLY B 1 190 ? 22.742  -6.026  98.120  1.00 31.32  ? 209 GLY B N   1 
ATOM   4224  C CA  . GLY B 1 190 ? 21.777  -6.217  99.185  1.00 31.01  ? 209 GLY B CA  1 
ATOM   4225  C C   . GLY B 1 190 ? 21.192  -4.902  99.685  1.00 28.68  ? 209 GLY B C   1 
ATOM   4226  O O   . GLY B 1 190 ? 20.076  -4.859  100.216 1.00 29.08  ? 209 GLY B O   1 
ATOM   4227  N N   . LEU B 1 191 ? 21.937  -3.806  99.546  1.00 32.83  ? 210 LEU B N   1 
ATOM   4228  C CA  . LEU B 1 191 ? 21.355  -2.498  99.832  1.00 30.94  ? 210 LEU B CA  1 
ATOM   4229  C C   . LEU B 1 191 ? 20.203  -2.215  98.876  1.00 31.70  ? 210 LEU B C   1 
ATOM   4230  O O   . LEU B 1 191 ? 19.098  -1.831  99.272  1.00 31.52  ? 210 LEU B O   1 
ATOM   4231  C CB  . LEU B 1 191 ? 22.438  -1.429  99.695  1.00 29.69  ? 210 LEU B CB  1 
ATOM   4232  C CG  . LEU B 1 191 ? 22.005  0.035   99.848  1.00 28.37  ? 210 LEU B CG  1 
ATOM   4233  C CD1 . LEU B 1 191 ? 21.223  0.224   101.141 1.00 27.72  ? 210 LEU B CD1 1 
ATOM   4234  C CD2 . LEU B 1 191 ? 23.202  0.966   99.849  1.00 28.32  ? 210 LEU B CD2 1 
ATOM   4235  N N   . GLN B 1 192 ? 20.450  -2.429  97.600  1.00 32.66  ? 211 GLN B N   1 
ATOM   4236  C CA  . GLN B 1 192 ? 19.420  -2.239  96.601  1.00 33.61  ? 211 GLN B CA  1 
ATOM   4237  C C   . GLN B 1 192 ? 18.216  -3.096  96.881  1.00 34.96  ? 211 GLN B C   1 
ATOM   4238  O O   . GLN B 1 192 ? 17.084  -2.631  96.827  1.00 35.13  ? 211 GLN B O   1 
ATOM   4239  C CB  . GLN B 1 192 ? 20.037  -2.551  95.267  1.00 34.67  ? 211 GLN B CB  1 
ATOM   4240  C CG  . GLN B 1 192 ? 19.139  -2.340  94.109  1.00 35.85  ? 211 GLN B CG  1 
ATOM   4241  C CD  . GLN B 1 192 ? 19.862  -1.804  92.875  1.00 35.83  ? 211 GLN B CD  1 
ATOM   4242  O OE1 . GLN B 1 192 ? 19.335  -1.833  91.760  1.00 35.63  ? 211 GLN B OE1 1 
ATOM   4243  N NE2 . GLN B 1 192 ? 21.100  -1.288  93.084  1.00 37.05  ? 211 GLN B NE2 1 
ATOM   4244  N N   . ASP B 1 193 ? 18.454  -4.330  97.281  1.00 29.93  ? 212 ASP B N   1 
ATOM   4245  C CA  . ASP B 1 193 ? 17.381  -5.283  97.537  1.00 32.02  ? 212 ASP B CA  1 
ATOM   4246  C C   . ASP B 1 193 ? 16.671  -4.994  98.844  1.00 31.20  ? 212 ASP B C   1 
ATOM   4247  O O   . ASP B 1 193 ? 15.483  -5.252  98.934  1.00 32.85  ? 212 ASP B O   1 
ATOM   4248  C CB  . ASP B 1 193 ? 17.972  -6.699  97.495  1.00 34.27  ? 212 ASP B CB  1 
ATOM   4249  C CG  . ASP B 1 193 ? 18.307  -7.150  96.056  1.00 36.32  ? 212 ASP B CG  1 
ATOM   4250  O OD1 . ASP B 1 193 ? 17.664  -6.634  95.090  1.00 37.56  ? 212 ASP B OD1 1 
ATOM   4251  O OD2 . ASP B 1 193 ? 19.213  -8.007  95.862  1.00 37.29  ? 212 ASP B OD2 1 
ATOM   4252  N N   . ILE B 1 194 ? 17.349  -4.396  99.834  1.00 32.60  ? 213 ILE B N   1 
ATOM   4253  C CA  . ILE B 1 194 ? 16.675  -4.118  101.110 1.00 31.84  ? 213 ILE B CA  1 
ATOM   4254  C C   . ILE B 1 194 ? 15.733  -2.931  100.993 1.00 31.12  ? 213 ILE B C   1 
ATOM   4255  O O   . ILE B 1 194 ? 14.713  -2.840  101.695 1.00 31.60  ? 213 ILE B O   1 
ATOM   4256  C CB  . ILE B 1 194 ? 17.695  -3.898  102.241 1.00 29.89  ? 213 ILE B CB  1 
ATOM   4257  C CG1 . ILE B 1 194 ? 17.056  -4.297  103.569 1.00 29.51  ? 213 ILE B CG1 1 
ATOM   4258  C CG2 . ILE B 1 194 ? 18.142  -2.480  102.307 1.00 27.96  ? 213 ILE B CG2 1 
ATOM   4259  C CD1 . ILE B 1 194 ? 18.008  -4.240  104.720 1.00 28.05  ? 213 ILE B CD1 1 
ATOM   4260  N N   . ILE B 1 195 ? 16.051  -1.997  100.115 1.00 32.21  ? 214 ILE B N   1 
ATOM   4261  C CA  . ILE B 1 195 ? 15.129  -0.891  99.871  1.00 31.49  ? 214 ILE B CA  1 
ATOM   4262  C C   . ILE B 1 195 ? 13.851  -1.437  99.268  1.00 33.55  ? 214 ILE B C   1 
ATOM   4263  O O   . ILE B 1 195 ? 12.741  -1.185  99.754  1.00 33.95  ? 214 ILE B O   1 
ATOM   4264  C CB  . ILE B 1 195 ? 15.774  0.168   98.959  1.00 30.36  ? 214 ILE B CB  1 
ATOM   4265  C CG1 . ILE B 1 195 ? 17.053  0.718   99.555  1.00 28.81  ? 214 ILE B CG1 1 
ATOM   4266  C CG2 . ILE B 1 195 ? 14.843  1.336   98.764  1.00 30.49  ? 214 ILE B CG2 1 
ATOM   4267  C CD1 . ILE B 1 195 ? 17.980  1.374   98.523  1.00 28.78  ? 214 ILE B CD1 1 
ATOM   4268  N N   . GLN B 1 196 ? 14.006  -2.225  98.201  1.00 29.38  ? 215 GLN B N   1 
ATOM   4269  C CA  . GLN B 1 196 ? 12.845  -2.842  97.517  1.00 31.58  ? 215 GLN B CA  1 
ATOM   4270  C C   . GLN B 1 196 ? 12.040  -3.671  98.524  1.00 33.46  ? 215 GLN B C   1 
ATOM   4271  O O   . GLN B 1 196 ? 10.822  -3.750  98.347  1.00 33.90  ? 215 GLN B O   1 
ATOM   4272  C CB  . GLN B 1 196 ? 13.325  -3.735  96.377  1.00 33.33  ? 215 GLN B CB  1 
ATOM   4273  C CG  . GLN B 1 196 ? 12.190  -4.396  95.605  1.00 34.57  ? 215 GLN B CG  1 
ATOM   4274  C CD  . GLN B 1 196 ? 12.646  -5.467  94.642  1.00 36.04  ? 215 GLN B CD  1 
ATOM   4275  O OE1 . GLN B 1 196 ? 13.833  -5.796  94.545  1.00 37.67  ? 215 GLN B OE1 1 
ATOM   4276  N NE2 . GLN B 1 196 ? 11.686  -6.033  93.927  1.00 35.87  ? 215 GLN B NE2 1 
ATOM   4277  N N   . GLU B 1 197 ? 12.701  -4.295  99.500  1.00 34.24  ? 216 GLU B N   1 
ATOM   4278  C CA  . GLU B 1 197 ? 12.022  -5.144  100.515 1.00 34.34  ? 216 GLU B CA  1 
ATOM   4279  C C   . GLU B 1 197 ? 11.348  -4.248  101.561 1.00 33.11  ? 216 GLU B C   1 
ATOM   4280  O O   . GLU B 1 197 ? 10.279  -4.646  102.054 1.00 33.93  ? 216 GLU B O   1 
ATOM   4281  C CB  . GLU B 1 197 ? 13.030  -6.104  101.141 1.00 34.44  ? 216 GLU B CB  1 
ATOM   4282  C CG  . GLU B 1 197 ? 13.388  -7.259  100.212 1.00 35.43  ? 216 GLU B CG  1 
ATOM   4283  C CD  . GLU B 1 197 ? 14.491  -8.162  100.725 1.00 35.91  ? 216 GLU B CD  1 
ATOM   4284  O OE1 . GLU B 1 197 ? 14.889  -7.996  101.895 1.00 37.11  ? 216 GLU B OE1 1 
ATOM   4285  O OE2 . GLU B 1 197 ? 14.963  -9.016  99.947  1.00 36.20  ? 216 GLU B OE2 1 
ATOM   4286  N N   . THR B 1 198 ? 11.948  -3.107  101.905 1.00 33.75  ? 217 THR B N   1 
ATOM   4287  C CA  . THR B 1 198 ? 11.346  -2.135  102.838 1.00 32.96  ? 217 THR B CA  1 
ATOM   4288  C C   . THR B 1 198 ? 10.048  -1.697  102.219 1.00 34.34  ? 217 THR B C   1 
ATOM   4289  O O   . THR B 1 198 ? 9.077   -1.686  102.945 1.00 35.00  ? 217 THR B O   1 
ATOM   4290  C CB  . THR B 1 198 ? 12.267  -0.939  103.073 1.00 30.61  ? 217 THR B CB  1 
ATOM   4291  O OG1 . THR B 1 198 ? 13.412  -1.429  103.757 1.00 29.39  ? 217 THR B OG1 1 
ATOM   4292  C CG2 . THR B 1 198 ? 11.610  0.144   103.911 1.00 30.12  ? 217 THR B CG2 1 
ATOM   4293  N N   . ARG B 1 199 ? 10.042  -1.350  100.931 1.00 32.34  ? 218 ARG B N   1 
ATOM   4294  C CA  . ARG B 1 199 ? 8.866   -0.899  100.189 1.00 32.81  ? 218 ARG B CA  1 
ATOM   4295  C C   . ARG B 1 199 ? 7.794   -1.972  100.170 1.00 35.15  ? 218 ARG B C   1 
ATOM   4296  O O   . ARG B 1 199 ? 6.651   -1.713  100.561 1.00 36.39  ? 218 ARG B O   1 
ATOM   4297  C CB  . ARG B 1 199 ? 9.276   -0.494  98.772  1.00 32.16  ? 218 ARG B CB  1 
ATOM   4298  C CG  . ARG B 1 199 ? 8.132   -0.116  97.821  1.00 32.89  ? 218 ARG B CG  1 
ATOM   4299  C CD  . ARG B 1 199 ? 7.302   1.037   98.316  1.00 32.64  ? 218 ARG B CD  1 
ATOM   4300  N NE  . ARG B 1 199 ? 8.097   2.257   98.423  1.00 31.83  ? 218 ARG B NE  1 
ATOM   4301  C CZ  . ARG B 1 199 ? 7.711   3.335   99.083  1.00 31.96  ? 218 ARG B CZ  1 
ATOM   4302  N NH1 . ARG B 1 199 ? 6.543   3.369   99.716  1.00 32.76  ? 218 ARG B NH1 1 
ATOM   4303  N NH2 . ARG B 1 199 ? 8.503   4.413   99.088  1.00 31.52  ? 218 ARG B NH2 1 
ATOM   4304  N N   . GLN B 1 200 ? 8.147   -3.197  99.724  1.00 34.25  ? 219 GLN B N   1 
ATOM   4305  C CA  . GLN B 1 200 ? 7.166   -4.283  99.660  1.00 36.23  ? 219 GLN B CA  1 
ATOM   4306  C C   . GLN B 1 200 ? 6.420   -4.409  100.981 1.00 36.72  ? 219 GLN B C   1 
ATOM   4307  O O   . GLN B 1 200 ? 5.207   -4.628  101.027 1.00 38.53  ? 219 GLN B O   1 
ATOM   4308  C CB  . GLN B 1 200 ? 7.844   -5.622  99.369  1.00 37.23  ? 219 GLN B CB  1 
ATOM   4309  C CG  . GLN B 1 200 ? 8.201   -5.993  97.922  1.00 38.58  ? 219 GLN B CG  1 
ATOM   4310  C CD  . GLN B 1 200 ? 9.538   -6.788  97.818  1.00 39.11  ? 219 GLN B CD  1 
ATOM   4311  O OE1 . GLN B 1 200 ? 10.260  -6.678  96.799  1.00 38.67  ? 219 GLN B OE1 1 
ATOM   4312  N NE2 . GLN B 1 200 ? 9.861   -7.604  98.857  1.00 40.18  ? 219 GLN B NE2 1 
ATOM   4313  N N   . LYS B 1 201 ? 7.135   -4.253  102.060 1.00 36.14  ? 220 LYS B N   1 
ATOM   4314  C CA  . LYS B 1 201 ? 6.617   -4.527  103.380 1.00 36.38  ? 220 LYS B CA  1 
ATOM   4315  C C   . LYS B 1 201 ? 5.896   -3.351  104.008 1.00 35.98  ? 220 LYS B C   1 
ATOM   4316  O O   . LYS B 1 201 ? 4.942   -3.561  104.752 1.00 37.49  ? 220 LYS B O   1 
ATOM   4317  C CB  . LYS B 1 201 ? 7.789   -4.977  104.260 1.00 35.92  ? 220 LYS B CB  1 
ATOM   4318  C CG  . LYS B 1 201 ? 7.352   -5.873  105.367 1.00 37.17  ? 220 LYS B CG  1 
ATOM   4319  C CD  . LYS B 1 201 ? 8.429   -6.778  105.858 1.00 37.06  ? 220 LYS B CD  1 
ATOM   4320  C CE  . LYS B 1 201 ? 8.905   -7.816  104.885 1.00 38.34  ? 220 LYS B CE  1 
ATOM   4321  N NZ  . LYS B 1 201 ? 10.166  -8.424  105.561 1.00 36.89  ? 220 LYS B NZ  1 
ATOM   4322  N N   . ILE B 1 202 ? 6.288   -2.114  103.724 1.00 36.75  ? 221 ILE B N   1 
ATOM   4323  C CA  . ILE B 1 202 ? 5.539   -0.998  104.306 1.00 36.78  ? 221 ILE B CA  1 
ATOM   4324  C C   . ILE B 1 202 ? 4.460   -0.438  103.381 1.00 37.92  ? 221 ILE B C   1 
ATOM   4325  O O   . ILE B 1 202 ? 3.563   0.275   103.840 1.00 38.54  ? 221 ILE B O   1 
ATOM   4326  C CB  . ILE B 1 202 ? 6.485   0.142   104.741 1.00 35.18  ? 221 ILE B CB  1 
ATOM   4327  C CG1 . ILE B 1 202 ? 7.091   0.869   103.531 1.00 33.85  ? 221 ILE B CG1 1 
ATOM   4328  C CG2 . ILE B 1 202 ? 7.637   -0.382  105.590 1.00 34.30  ? 221 ILE B CG2 1 
ATOM   4329  C CD1 . ILE B 1 202 ? 7.962   1.996   103.917 1.00 31.89  ? 221 ILE B CD1 1 
ATOM   4330  N N   . GLY B 1 203 ? 4.503   -0.741  102.097 1.00 36.71  ? 222 GLY B N   1 
ATOM   4331  C CA  . GLY B 1 203 ? 3.444   -0.311  101.211 1.00 36.79  ? 222 GLY B CA  1 
ATOM   4332  C C   . GLY B 1 203 ? 3.717   1.022   100.524 1.00 36.16  ? 222 GLY B C   1 
ATOM   4333  O O   . GLY B 1 203 ? 4.493   1.857   100.984 1.00 35.81  ? 222 GLY B O   1 
ATOM   4334  N N   . ASP B 1 204 ? 3.027   1.207   99.390  1.00 37.01  ? 223 ASP B N   1 
ATOM   4335  C CA  . ASP B 1 204 ? 3.180   2.342   98.503  1.00 36.40  ? 223 ASP B CA  1 
ATOM   4336  C C   . ASP B 1 204 ? 2.729   3.656   99.125  1.00 36.81  ? 223 ASP B C   1 
ATOM   4337  O O   . ASP B 1 204 ? 3.073   4.718   98.601  1.00 37.01  ? 223 ASP B O   1 
ATOM   4338  C CB  . ASP B 1 204 ? 2.343   2.117   97.235  1.00 37.14  ? 223 ASP B CB  1 
ATOM   4339  C CG  . ASP B 1 204 ? 2.808   0.917   96.369  1.00 37.53  ? 223 ASP B CG  1 
ATOM   4340  O OD1 . ASP B 1 204 ? 4.014   0.579   96.328  1.00 36.96  ? 223 ASP B OD1 1 
ATOM   4341  O OD2 . ASP B 1 204 ? 1.943   0.339   95.690  1.00 39.55  ? 223 ASP B OD2 1 
ATOM   4342  N N   . ASP B 1 205 ? 1.936   3.629   100.187 1.00 38.11  ? 224 ASP B N   1 
ATOM   4343  C CA  . ASP B 1 205 ? 1.443   4.867   100.797 1.00 38.75  ? 224 ASP B CA  1 
ATOM   4344  C C   . ASP B 1 205 ? 2.325   5.376   101.950 1.00 37.76  ? 224 ASP B C   1 
ATOM   4345  O O   . ASP B 1 205 ? 1.879   6.217   102.729 1.00 38.52  ? 224 ASP B O   1 
ATOM   4346  C CB  . ASP B 1 205 ? 0.019   4.667   101.334 1.00 41.35  ? 224 ASP B CB  1 
ATOM   4347  C CG  . ASP B 1 205 ? -0.046  3.618   102.467 1.00 42.88  ? 224 ASP B CG  1 
ATOM   4348  O OD1 . ASP B 1 205 ? 0.559   2.510   102.337 1.00 42.03  ? 224 ASP B OD1 1 
ATOM   4349  O OD2 . ASP B 1 205 ? -0.690  3.919   103.507 1.00 45.89  ? 224 ASP B OD2 1 
ATOM   4350  N N   . LYS B 1 206 ? 3.551   4.890   102.068 1.00 36.16  ? 225 LYS B N   1 
ATOM   4351  C CA  . LYS B 1 206 ? 4.466   5.223   103.139 1.00 35.57  ? 225 LYS B CA  1 
ATOM   4352  C C   . LYS B 1 206 ? 5.719   5.829   102.520 1.00 34.34  ? 225 LYS B C   1 
ATOM   4353  O O   . LYS B 1 206 ? 6.016   5.663   101.334 1.00 34.35  ? 225 LYS B O   1 
ATOM   4354  C CB  . LYS B 1 206 ? 4.826   3.997   103.974 1.00 36.24  ? 225 LYS B CB  1 
ATOM   4355  C CG  . LYS B 1 206 ? 3.637   3.346   104.652 1.00 37.38  ? 225 LYS B CG  1 
ATOM   4356  C CD  . LYS B 1 206 ? 3.065   4.211   105.763 1.00 38.07  ? 225 LYS B CD  1 
ATOM   4357  C CE  . LYS B 1 206 ? 1.891   3.521   106.445 1.00 39.75  ? 225 LYS B CE  1 
ATOM   4358  N NZ  . LYS B 1 206 ? 1.464   4.199   107.688 1.00 40.81  ? 225 LYS B NZ  1 
ATOM   4359  N N   . LEU B 1 207 ? 6.443   6.568   103.336 1.00 35.53  ? 226 LEU B N   1 
ATOM   4360  C CA  . LEU B 1 207 ? 7.570   7.341   102.867 1.00 34.13  ? 226 LEU B CA  1 
ATOM   4361  C C   . LEU B 1 207 ? 8.853   6.600   103.184 1.00 34.34  ? 226 LEU B C   1 
ATOM   4362  O O   . LEU B 1 207 ? 9.036   6.085   104.301 1.00 35.24  ? 226 LEU B O   1 
ATOM   4363  C CB  . LEU B 1 207 ? 7.569   8.726   103.512 1.00 33.27  ? 226 LEU B CB  1 
ATOM   4364  C CG  . LEU B 1 207 ? 6.443   9.585   102.911 1.00 33.26  ? 226 LEU B CG  1 
ATOM   4365  C CD1 . LEU B 1 207 ? 6.158   10.809  103.768 1.00 33.07  ? 226 LEU B CD1 1 
ATOM   4366  C CD2 . LEU B 1 207 ? 6.814   9.992   101.467 1.00 32.85  ? 226 LEU B CD2 1 
ATOM   4367  N N   . ILE B 1 208 ? 9.718   6.519   102.185 1.00 31.45  ? 227 ILE B N   1 
ATOM   4368  C CA  . ILE B 1 208 ? 11.065  6.017   102.359 1.00 31.80  ? 227 ILE B CA  1 
ATOM   4369  C C   . ILE B 1 208 ? 11.971  7.188   102.053 1.00 30.90  ? 227 ILE B C   1 
ATOM   4370  O O   . ILE B 1 208 ? 12.029  7.653   100.899 1.00 30.44  ? 227 ILE B O   1 
ATOM   4371  C CB  . ILE B 1 208 ? 11.379  4.820   101.456 1.00 32.62  ? 227 ILE B CB  1 
ATOM   4372  C CG1 . ILE B 1 208 ? 10.548  3.619   101.867 1.00 33.51  ? 227 ILE B CG1 1 
ATOM   4373  C CG2 . ILE B 1 208 ? 12.850  4.470   101.563 1.00 33.32  ? 227 ILE B CG2 1 
ATOM   4374  C CD1 . ILE B 1 208 ? 10.871  2.327   101.043 1.00 33.91  ? 227 ILE B CD1 1 
ATOM   4375  N N   . VAL B 1 209 ? 12.637  7.700   103.093 1.00 30.64  ? 228 VAL B N   1 
ATOM   4376  C CA  . VAL B 1 209 ? 13.669  8.725   102.996 1.00 30.04  ? 228 VAL B CA  1 
ATOM   4377  C C   . VAL B 1 209 ? 15.006  8.025   103.170 1.00 31.16  ? 228 VAL B C   1 
ATOM   4378  O O   . VAL B 1 209 ? 15.112  7.086   103.965 1.00 32.07  ? 228 VAL B O   1 
ATOM   4379  C CB  . VAL B 1 209 ? 13.481  9.804   104.076 1.00 29.40  ? 228 VAL B CB  1 
ATOM   4380  C CG1 . VAL B 1 209 ? 14.461  10.960  103.819 1.00 28.45  ? 228 VAL B CG1 1 
ATOM   4381  C CG2 . VAL B 1 209 ? 12.042  10.329  104.152 1.00 28.69  ? 228 VAL B CG2 1 
ATOM   4382  N N   . TYR B 1 210 ? 16.033  8.471   102.463 1.00 30.38  ? 229 TYR B N   1 
ATOM   4383  C CA  . TYR B 1 210 ? 17.347  7.902   102.704 1.00 30.97  ? 229 TYR B CA  1 
ATOM   4384  C C   . TYR B 1 210 ? 18.450  8.954   102.714 1.00 30.74  ? 229 TYR B C   1 
ATOM   4385  O O   . TYR B 1 210 ? 18.277  10.092  102.261 1.00 30.44  ? 229 TYR B O   1 
ATOM   4386  C CB  . TYR B 1 210 ? 17.659  6.843   101.679 1.00 31.72  ? 229 TYR B CB  1 
ATOM   4387  C CG  . TYR B 1 210 ? 18.214  7.288   100.370 1.00 31.47  ? 229 TYR B CG  1 
ATOM   4388  C CD1 . TYR B 1 210 ? 17.372  7.545   99.290  1.00 31.23  ? 229 TYR B CD1 1 
ATOM   4389  C CD2 . TYR B 1 210 ? 19.570  7.308   100.149 1.00 32.05  ? 229 TYR B CD2 1 
ATOM   4390  C CE1 . TYR B 1 210 ? 17.876  7.875   98.041  1.00 31.59  ? 229 TYR B CE1 1 
ATOM   4391  C CE2 . TYR B 1 210 ? 20.076  7.650   98.922  1.00 32.38  ? 229 TYR B CE2 1 
ATOM   4392  C CZ  . TYR B 1 210 ? 19.229  7.930   97.868  1.00 32.28  ? 229 TYR B CZ  1 
ATOM   4393  O OH  . TYR B 1 210 ? 19.745  8.244   96.627  1.00 33.13  ? 229 TYR B OH  1 
ATOM   4394  N N   . ASN B 1 211 ? 19.590  8.565   103.261 1.00 31.31  ? 230 ASN B N   1 
ATOM   4395  C CA  . ASN B 1 211 ? 20.778  9.413   103.277 1.00 31.62  ? 230 ASN B CA  1 
ATOM   4396  C C   . ASN B 1 211 ? 21.898  8.669   102.564 1.00 32.33  ? 230 ASN B C   1 
ATOM   4397  O O   . ASN B 1 211 ? 22.401  7.652   103.076 1.00 32.76  ? 230 ASN B O   1 
ATOM   4398  C CB  . ASN B 1 211 ? 21.187  9.778   104.717 1.00 31.60  ? 230 ASN B CB  1 
ATOM   4399  C CG  . ASN B 1 211 ? 22.232  10.857  104.760 1.00 32.27  ? 230 ASN B CG  1 
ATOM   4400  O OD1 . ASN B 1 211 ? 22.572  11.445  103.733 1.00 33.07  ? 230 ASN B OD1 1 
ATOM   4401  N ND2 . ASN B 1 211 ? 22.749  11.138  105.943 1.00 32.36  ? 230 ASN B ND2 1 
ATOM   4402  N N   . GLY B 1 212 ? 22.305  9.186   101.397 1.00 31.98  ? 231 GLY B N   1 
ATOM   4403  C CA  . GLY B 1 212 ? 21.770  10.356  100.734 1.00 31.40  ? 231 GLY B CA  1 
ATOM   4404  C C   . GLY B 1 212 ? 22.587  10.907  99.570  1.00 31.67  ? 231 GLY B C   1 
ATOM   4405  O O   . GLY B 1 212 ? 23.468  10.251  99.052  1.00 32.48  ? 231 GLY B O   1 
ATOM   4406  N N   . ILE B 1 213 ? 22.290  12.128  99.153  1.00 34.34  ? 232 ILE B N   1 
ATOM   4407  C CA  . ILE B 1 213 ? 23.105  12.800  98.152  1.00 34.39  ? 232 ILE B CA  1 
ATOM   4408  C C   . ILE B 1 213 ? 24.350  13.307  98.841  1.00 35.11  ? 232 ILE B C   1 
ATOM   4409  O O   . ILE B 1 213 ? 24.277  13.831  99.952  1.00 35.11  ? 232 ILE B O   1 
ATOM   4410  C CB  . ILE B 1 213 ? 22.339  13.964  97.487  1.00 33.23  ? 232 ILE B CB  1 
ATOM   4411  C CG1 . ILE B 1 213 ? 21.157  13.442  96.668  1.00 33.17  ? 232 ILE B CG1 1 
ATOM   4412  C CG2 . ILE B 1 213 ? 23.248  14.771  96.577  1.00 33.79  ? 232 ILE B CG2 1 
ATOM   4413  C CD1 . ILE B 1 213 ? 20.073  14.444  96.551  1.00 31.90  ? 232 ILE B CD1 1 
ATOM   4414  N N   . ARG B 1 214 ? 25.483  13.178  98.175  1.00 34.54  ? 233 ARG B N   1 
ATOM   4415  C CA  . ARG B 1 214 ? 26.736  13.539  98.796  1.00 35.74  ? 233 ARG B CA  1 
ATOM   4416  C C   . ARG B 1 214 ? 27.736  13.910  97.727  1.00 36.23  ? 233 ARG B C   1 
ATOM   4417  O O   . ARG B 1 214 ? 28.110  13.070  96.920  1.00 36.89  ? 233 ARG B O   1 
ATOM   4418  C CB  . ARG B 1 214 ? 27.252  12.386  99.626  1.00 37.03  ? 233 ARG B CB  1 
ATOM   4419  C CG  . ARG B 1 214 ? 28.578  12.621  100.284 1.00 38.96  ? 233 ARG B CG  1 
ATOM   4420  C CD  . ARG B 1 214 ? 28.420  13.618  101.420 1.00 39.21  ? 233 ARG B CD  1 
ATOM   4421  N NE  . ARG B 1 214 ? 27.333  13.270  102.339 1.00 38.46  ? 233 ARG B NE  1 
ATOM   4422  C CZ  . ARG B 1 214 ? 27.429  12.403  103.327 1.00 39.06  ? 233 ARG B CZ  1 
ATOM   4423  N NH1 . ARG B 1 214 ? 28.554  11.741  103.544 1.00 40.12  ? 233 ARG B NH1 1 
ATOM   4424  N NH2 . ARG B 1 214 ? 26.381  12.221  104.127 1.00 38.47  ? 233 ARG B NH2 1 
ATOM   4425  N N   . SER B 1 215 ? 28.226  15.134  97.772  1.00 40.19  ? 234 SER B N   1 
ATOM   4426  C CA  . SER B 1 215 ? 29.237  15.597  96.839  1.00 40.77  ? 234 SER B CA  1 
ATOM   4427  C C   . SER B 1 215 ? 30.523  15.889  97.588  1.00 42.34  ? 234 SER B C   1 
ATOM   4428  O O   . SER B 1 215 ? 30.534  16.717  98.500  1.00 42.49  ? 234 SER B O   1 
ATOM   4429  C CB  . SER B 1 215 ? 28.745  16.851  96.116  1.00 39.96  ? 234 SER B CB  1 
ATOM   4430  O OG  . SER B 1 215 ? 27.488  16.611  95.495  1.00 39.32  ? 234 SER B OG  1 
ATOM   4431  N N   . THR B 1 216 ? 31.600  15.229  97.198  1.00 40.77  ? 235 THR B N   1 
ATOM   4432  C CA  . THR B 1 216 ? 32.907  15.462  97.788  1.00 42.76  ? 235 THR B CA  1 
ATOM   4433  C C   . THR B 1 216 ? 33.926  15.423  96.663  1.00 44.17  ? 235 THR B C   1 
ATOM   4434  O O   . THR B 1 216 ? 33.657  14.868  95.587  1.00 44.40  ? 235 THR B O   1 
ATOM   4435  C CB  . THR B 1 216 ? 33.317  14.444  98.877  1.00 43.89  ? 235 THR B CB  1 
ATOM   4436  O OG1 . THR B 1 216 ? 33.738  13.193  98.294  1.00 44.86  ? 235 THR B OG1 1 
ATOM   4437  C CG2 . THR B 1 216 ? 32.212  14.192  99.877  1.00 43.22  ? 235 THR B CG2 1 
ATOM   4438  N N   . PRO B 1 217 ? 35.121  15.956  96.883  1.00 44.16  ? 236 PRO B N   1 
ATOM   4439  C CA  . PRO B 1 217 ? 36.109  15.912  95.810  1.00 45.95  ? 236 PRO B CA  1 
ATOM   4440  C C   . PRO B 1 217 ? 36.388  14.503  95.373  1.00 47.83  ? 236 PRO B C   1 
ATOM   4441  O O   . PRO B 1 217 ? 36.413  14.240  94.174  1.00 49.08  ? 236 PRO B O   1 
ATOM   4442  C CB  . PRO B 1 217 ? 37.330  16.595  96.430  1.00 47.15  ? 236 PRO B CB  1 
ATOM   4443  C CG  . PRO B 1 217 ? 36.717  17.542  97.415  1.00 46.39  ? 236 PRO B CG  1 
ATOM   4444  C CD  . PRO B 1 217 ? 35.579  16.766  98.017  1.00 44.94  ? 236 PRO B CD  1 
ATOM   4445  N N   . ASP B 1 218 ? 36.566  13.581  96.315  1.00 47.82  ? 237 ASP B N   1 
ATOM   4446  C CA  . ASP B 1 218 ? 37.052  12.242  96.033  1.00 49.73  ? 237 ASP B CA  1 
ATOM   4447  C C   . ASP B 1 218 ? 35.914  11.256  95.826  1.00 48.87  ? 237 ASP B C   1 
ATOM   4448  O O   . ASP B 1 218 ? 36.149  10.152  95.323  1.00 49.85  ? 237 ASP B O   1 
ATOM   4449  C CB  . ASP B 1 218 ? 37.985  11.799  97.171  1.00 51.66  ? 237 ASP B CB  1 
ATOM   4450  N N   . TRP B 1 219 ? 34.679  11.639  96.139  1.00 46.39  ? 238 TRP B N   1 
ATOM   4451  C CA  . TRP B 1 219 ? 33.560  10.723  95.958  1.00 44.99  ? 238 TRP B CA  1 
ATOM   4452  C C   . TRP B 1 219 ? 32.252  11.510  95.977  1.00 43.02  ? 238 TRP B C   1 
ATOM   4453  O O   . TRP B 1 219 ? 32.003  12.325  96.876  1.00 42.71  ? 238 TRP B O   1 
ATOM   4454  C CB  . TRP B 1 219 ? 33.555  9.673   97.059  1.00 45.48  ? 238 TRP B CB  1 
ATOM   4455  C CG  . TRP B 1 219 ? 32.503  8.627   96.930  1.00 44.85  ? 238 TRP B CG  1 
ATOM   4456  C CD1 . TRP B 1 219 ? 32.624  7.436   96.254  1.00 45.48  ? 238 TRP B CD1 1 
ATOM   4457  C CD2 . TRP B 1 219 ? 31.172  8.630   97.489  1.00 43.56  ? 238 TRP B CD2 1 
ATOM   4458  N NE1 . TRP B 1 219 ? 31.459  6.697   96.369  1.00 44.73  ? 238 TRP B NE1 1 
ATOM   4459  C CE2 . TRP B 1 219 ? 30.557  7.403   97.121  1.00 43.40  ? 238 TRP B CE2 1 
ATOM   4460  C CE3 . TRP B 1 219 ? 30.449  9.533   98.260  1.00 42.47  ? 238 TRP B CE3 1 
ATOM   4461  C CZ2 . TRP B 1 219 ? 29.243  7.065   97.503  1.00 42.15  ? 238 TRP B CZ2 1 
ATOM   4462  C CZ3 . TRP B 1 219 ? 29.136  9.196   98.643  1.00 41.39  ? 238 TRP B CZ3 1 
ATOM   4463  C CH2 . TRP B 1 219 ? 28.550  7.979   98.255  1.00 41.32  ? 238 TRP B CH2 1 
ATOM   4464  N N   . SER B 1 220 ? 31.407  11.250  95.002  1.00 44.44  ? 239 SER B N   1 
ATOM   4465  C CA  . SER B 1 220 ? 30.087  11.853  94.951  1.00 42.68  ? 239 SER B CA  1 
ATOM   4466  C C   . SER B 1 220 ? 29.035  10.790  94.681  1.00 41.25  ? 239 SER B C   1 
ATOM   4467  O O   . SER B 1 220 ? 29.324  9.735   94.099  1.00 42.49  ? 239 SER B O   1 
ATOM   4468  C CB  . SER B 1 220 ? 30.043  12.910  93.890  1.00 43.03  ? 239 SER B CB  1 
ATOM   4469  O OG  . SER B 1 220 ? 30.996  13.909  94.179  1.00 44.06  ? 239 SER B OG  1 
ATOM   4470  N N   . ALA B 1 221 ? 27.824  11.097  95.141  1.00 39.98  ? 240 ALA B N   1 
ATOM   4471  C CA  . ALA B 1 221 ? 26.633  10.307  94.936  1.00 38.93  ? 240 ALA B CA  1 
ATOM   4472  C C   . ALA B 1 221 ? 25.440  11.231  94.791  1.00 37.30  ? 240 ALA B C   1 
ATOM   4473  O O   . ALA B 1 221 ? 25.219  12.083  95.653  1.00 36.61  ? 240 ALA B O   1 
ATOM   4474  C CB  . ALA B 1 221 ? 26.402  9.367   96.117  1.00 39.51  ? 240 ALA B CB  1 
ATOM   4475  N N   . GLY B 1 222 ? 24.675  11.052  93.729  1.00 38.12  ? 241 GLY B N   1 
ATOM   4476  C CA  . GLY B 1 222 ? 23.414  11.742  93.545  1.00 37.08  ? 241 GLY B CA  1 
ATOM   4477  C C   . GLY B 1 222 ? 22.247  10.977  94.142  1.00 36.53  ? 241 GLY B C   1 
ATOM   4478  O O   . GLY B 1 222 ? 22.408  10.143  95.037  1.00 37.10  ? 241 GLY B O   1 
ATOM   4479  N N   . PHE B 1 223 ? 21.046  11.291  93.650  1.00 36.24  ? 242 PHE B N   1 
ATOM   4480  C CA  . PHE B 1 223 ? 19.821  10.545  93.959  1.00 35.60  ? 242 PHE B CA  1 
ATOM   4481  C C   . PHE B 1 223 ? 19.846  9.282   93.094  1.00 36.84  ? 242 PHE B C   1 
ATOM   4482  O O   . PHE B 1 223 ? 19.288  9.227   91.987  1.00 37.84  ? 242 PHE B O   1 
ATOM   4483  C CB  . PHE B 1 223 ? 18.597  11.410  93.681  1.00 34.81  ? 242 PHE B CB  1 
ATOM   4484  C CG  . PHE B 1 223 ? 17.410  11.128  94.558  1.00 33.86  ? 242 PHE B CG  1 
ATOM   4485  C CD1 . PHE B 1 223 ? 16.954  9.839   94.756  1.00 34.99  ? 242 PHE B CD1 1 
ATOM   4486  C CD2 . PHE B 1 223 ? 16.722  12.155  95.132  1.00 32.89  ? 242 PHE B CD2 1 
ATOM   4487  C CE1 . PHE B 1 223 ? 15.839  9.604   95.529  1.00 34.87  ? 242 PHE B CE1 1 
ATOM   4488  C CE2 . PHE B 1 223 ? 15.610  11.922  95.888  1.00 32.89  ? 242 PHE B CE2 1 
ATOM   4489  C CZ  . PHE B 1 223 ? 15.166  10.650  96.091  1.00 33.70  ? 242 PHE B CZ  1 
ATOM   4490  N N   . ASP B 1 224 ? 20.540  8.265   93.607  1.00 36.71  ? 243 ASP B N   1 
ATOM   4491  C CA  . ASP B 1 224 ? 20.915  7.079   92.843  1.00 38.27  ? 243 ASP B CA  1 
ATOM   4492  C C   . ASP B 1 224 ? 20.034  5.871   93.112  1.00 37.85  ? 243 ASP B C   1 
ATOM   4493  O O   . ASP B 1 224 ? 19.871  5.032   92.221  1.00 39.67  ? 243 ASP B O   1 
ATOM   4494  C CB  . ASP B 1 224 ? 22.367  6.704   93.156  1.00 40.53  ? 243 ASP B CB  1 
ATOM   4495  C CG  . ASP B 1 224 ? 23.349  7.748   92.664  1.00 42.27  ? 243 ASP B CG  1 
ATOM   4496  O OD1 . ASP B 1 224 ? 22.896  8.671   91.949  1.00 42.35  ? 243 ASP B OD1 1 
ATOM   4497  O OD2 . ASP B 1 224 ? 24.559  7.663   92.975  1.00 43.45  ? 243 ASP B OD2 1 
ATOM   4498  N N   . PHE B 1 225 ? 19.478  5.753   94.308  1.00 35.70  ? 244 PHE B N   1 
ATOM   4499  C CA  . PHE B 1 225 ? 18.501  4.730   94.621  1.00 35.79  ? 244 PHE B CA  1 
ATOM   4500  C C   . PHE B 1 225 ? 17.138  5.384   94.489  1.00 34.87  ? 244 PHE B C   1 
ATOM   4501  O O   . PHE B 1 225 ? 16.541  5.786   95.482  1.00 34.26  ? 244 PHE B O   1 
ATOM   4502  C CB  . PHE B 1 225 ? 18.698  4.165   96.026  1.00 36.45  ? 244 PHE B CB  1 
ATOM   4503  C CG  . PHE B 1 225 ? 20.073  3.653   96.272  1.00 37.41  ? 244 PHE B CG  1 
ATOM   4504  C CD1 . PHE B 1 225 ? 21.086  4.520   96.561  1.00 37.01  ? 244 PHE B CD1 1 
ATOM   4505  C CD2 . PHE B 1 225 ? 20.342  2.306   96.203  1.00 39.10  ? 244 PHE B CD2 1 
ATOM   4506  C CE1 . PHE B 1 225 ? 22.340  4.067   96.782  1.00 37.88  ? 244 PHE B CE1 1 
ATOM   4507  C CE2 . PHE B 1 225 ? 21.602  1.849   96.414  1.00 39.97  ? 244 PHE B CE2 1 
ATOM   4508  C CZ  . PHE B 1 225 ? 22.604  2.716   96.695  1.00 39.36  ? 244 PHE B CZ  1 
ATOM   4509  N N   . ALA B 1 226 ? 16.620  5.422   93.267  1.00 36.85  ? 245 ALA B N   1 
ATOM   4510  C CA  . ALA B 1 226 ? 15.346  6.064   92.964  1.00 36.57  ? 245 ALA B CA  1 
ATOM   4511  C C   . ALA B 1 226 ? 14.158  5.123   92.847  1.00 36.83  ? 245 ALA B C   1 
ATOM   4512  O O   . ALA B 1 226 ? 13.022  5.569   93.030  1.00 36.56  ? 245 ALA B O   1 
ATOM   4513  C CB  . ALA B 1 226 ? 15.445  6.819   91.636  1.00 37.10  ? 245 ALA B CB  1 
ATOM   4514  N N   . GLU B 1 227 ? 14.335  3.844   92.511  1.00 36.51  ? 246 GLU B N   1 
ATOM   4515  C CA  . GLU B 1 227 ? 13.173  3.068   92.097  1.00 36.81  ? 246 GLU B CA  1 
ATOM   4516  C C   . GLU B 1 227 ? 12.106  3.020   93.186  1.00 36.49  ? 246 GLU B C   1 
ATOM   4517  O O   . GLU B 1 227 ? 10.906  3.063   92.892  1.00 36.84  ? 246 GLU B O   1 
ATOM   4518  C CB  . GLU B 1 227 ? 13.574  1.668   91.663  1.00 37.41  ? 246 GLU B CB  1 
ATOM   4519  C CG  . GLU B 1 227 ? 12.411  0.940   90.997  1.00 39.64  ? 246 GLU B CG  1 
ATOM   4520  C CD  . GLU B 1 227 ? 12.798  -0.468  90.574  1.00 41.66  ? 246 GLU B CD  1 
ATOM   4521  O OE1 . GLU B 1 227 ? 13.905  -0.897  91.020  1.00 42.74  ? 246 GLU B OE1 1 
ATOM   4522  O OE2 . GLU B 1 227 ? 12.032  -1.142  89.817  1.00 41.87  ? 246 GLU B OE2 1 
ATOM   4523  N N   . TYR B 1 228 ? 12.511  2.903   94.448  1.00 33.39  ? 247 TYR B N   1 
ATOM   4524  C CA  . TYR B 1 228 ? 11.542  2.643   95.517  1.00 33.49  ? 247 TYR B CA  1 
ATOM   4525  C C   . TYR B 1 228 ? 11.589  3.663   96.647  1.00 32.72  ? 247 TYR B C   1 
ATOM   4526  O O   . TYR B 1 228 ? 10.827  3.562   97.615  1.00 33.52  ? 247 TYR B O   1 
ATOM   4527  C CB  . TYR B 1 228 ? 11.781  1.240   96.067  1.00 34.17  ? 247 TYR B CB  1 
ATOM   4528  C CG  . TYR B 1 228 ? 11.587  0.115   95.064  1.00 34.55  ? 247 TYR B CG  1 
ATOM   4529  C CD1 . TYR B 1 228 ? 10.330  -0.313  94.728  1.00 34.94  ? 247 TYR B CD1 1 
ATOM   4530  C CD2 . TYR B 1 228 ? 12.661  -0.521  94.491  1.00 34.89  ? 247 TYR B CD2 1 
ATOM   4531  C CE1 . TYR B 1 228 ? 10.135  -1.350  93.848  1.00 35.45  ? 247 TYR B CE1 1 
ATOM   4532  C CE2 . TYR B 1 228 ? 12.499  -1.537  93.635  1.00 35.58  ? 247 TYR B CE2 1 
ATOM   4533  C CZ  . TYR B 1 228 ? 11.236  -1.967  93.306  1.00 35.67  ? 247 TYR B CZ  1 
ATOM   4534  O OH  . TYR B 1 228 ? 11.092  -2.997  92.407  1.00 36.75  ? 247 TYR B OH  1 
ATOM   4535  N N   . THR B 1 229 ? 12.437  4.654   96.525  1.00 33.83  ? 248 THR B N   1 
ATOM   4536  C CA  . THR B 1 229 ? 12.574  5.704   97.521  1.00 33.35  ? 248 THR B CA  1 
ATOM   4537  C C   . THR B 1 229 ? 11.754  6.921   97.126  1.00 32.26  ? 248 THR B C   1 
ATOM   4538  O O   . THR B 1 229 ? 11.448  7.144   95.953  1.00 32.66  ? 248 THR B O   1 
ATOM   4539  C CB  . THR B 1 229 ? 14.032  6.116   97.678  1.00 33.88  ? 248 THR B CB  1 
ATOM   4540  O OG1 . THR B 1 229 ? 14.481  6.635   96.434  1.00 34.07  ? 248 THR B OG1 1 
ATOM   4541  C CG2 . THR B 1 229 ? 14.851  4.926   98.047  1.00 34.96  ? 248 THR B CG2 1 
ATOM   4542  N N   . ASP B 1 230 ? 11.439  7.725   98.128  1.00 34.47  ? 249 ASP B N   1 
ATOM   4543  C CA  . ASP B 1 230 ? 10.700  8.966   97.945  1.00 33.72  ? 249 ASP B CA  1 
ATOM   4544  C C   . ASP B 1 230 ? 11.568  10.193  98.092  1.00 33.12  ? 249 ASP B C   1 
ATOM   4545  O O   . ASP B 1 230 ? 11.429  11.147  97.322  1.00 32.44  ? 249 ASP B O   1 
ATOM   4546  C CB  . ASP B 1 230 ? 9.552   9.012   98.947  1.00 34.10  ? 249 ASP B CB  1 
ATOM   4547  C CG  . ASP B 1 230 ? 8.542   7.883   98.702  1.00 35.22  ? 249 ASP B CG  1 
ATOM   4548  O OD1 . ASP B 1 230 ? 8.117   7.725   97.510  1.00 35.80  ? 249 ASP B OD1 1 
ATOM   4549  O OD2 . ASP B 1 230 ? 8.198   7.151   99.672  1.00 35.82  ? 249 ASP B OD2 1 
ATOM   4550  N N   . ALA B 1 231 ? 12.512  10.134  99.021  1.00 32.43  ? 250 ALA B N   1 
ATOM   4551  C CA  . ALA B 1 231 ? 13.206  11.329  99.460  1.00 31.49  ? 250 ALA B CA  1 
ATOM   4552  C C   . ALA B 1 231 ? 14.645  10.990  99.770  1.00 32.01  ? 250 ALA B C   1 
ATOM   4553  O O   . ALA B 1 231 ? 14.925  9.949   100.357 1.00 33.27  ? 250 ALA B O   1 
ATOM   4554  C CB  . ALA B 1 231 ? 12.545  11.937  100.696 1.00 31.19  ? 250 ALA B CB  1 
ATOM   4555  N N   . ALA B 1 232 ? 15.540  11.890  99.403  1.00 31.96  ? 251 ALA B N   1 
ATOM   4556  C CA  . ALA B 1 232 ? 16.937  11.851  99.796  1.00 32.77  ? 251 ALA B CA  1 
ATOM   4557  C C   . ALA B 1 232 ? 17.338  13.138  100.528 1.00 32.13  ? 251 ALA B C   1 
ATOM   4558  O O   . ALA B 1 232 ? 16.795  14.226  100.271 1.00 30.92  ? 251 ALA B O   1 
ATOM   4559  C CB  . ALA B 1 232 ? 17.819  11.647  98.571  1.00 33.55  ? 251 ALA B CB  1 
ATOM   4560  N N   . MET B 1 233 ? 18.325  12.990  101.409 1.00 35.84  ? 252 MET B N   1 
ATOM   4561  C CA  . MET B 1 233 ? 18.880  14.101  102.174 1.00 35.35  ? 252 MET B CA  1 
ATOM   4562  C C   . MET B 1 233 ? 20.210  14.521  101.562 1.00 36.17  ? 252 MET B C   1 
ATOM   4563  O O   . MET B 1 233 ? 20.945  13.691  101.010 1.00 37.53  ? 252 MET B O   1 
ATOM   4564  C CB  . MET B 1 233 ? 19.025  13.705  103.655 1.00 36.68  ? 252 MET B CB  1 
ATOM   4565  C CG  . MET B 1 233 ? 20.009  14.525  104.495 1.00 36.91  ? 252 MET B CG  1 
ATOM   4566  S SD  . MET B 1 233 ? 19.823  14.472  106.353 1.00 36.73  ? 252 MET B SD  1 
ATOM   4567  C CE  . MET B 1 233 ? 17.996  14.577  106.450 1.00 36.15  ? 252 MET B CE  1 
ATOM   4568  N N   . ILE B 1 234 ? 20.465  15.834  101.586 1.00 35.26  ? 253 ILE B N   1 
ATOM   4569  C CA  . ILE B 1 234 ? 21.783  16.388  101.326 1.00 35.90  ? 253 ILE B CA  1 
ATOM   4570  C C   . ILE B 1 234 ? 22.305  16.819  102.689 1.00 36.58  ? 253 ILE B C   1 
ATOM   4571  O O   . ILE B 1 234 ? 22.084  17.970  103.109 1.00 35.59  ? 253 ILE B O   1 
ATOM   4572  C CB  . ILE B 1 234 ? 21.755  17.566  100.328 1.00 34.82  ? 253 ILE B CB  1 
ATOM   4573  C CG1 . ILE B 1 234 ? 21.053  17.125  99.032  1.00 34.61  ? 253 ILE B CG1 1 
ATOM   4574  C CG2 . ILE B 1 234 ? 23.162  18.006  100.014 1.00 36.33  ? 253 ILE B CG2 1 
ATOM   4575  C CD1 . ILE B 1 234 ? 20.755  18.278  98.025  1.00 33.80  ? 253 ILE B CD1 1 
ATOM   4576  N N   . GLU B 1 235 ? 22.940  15.888  103.399 1.00 36.71  ? 254 GLU B N   1 
ATOM   4577  C CA  . GLU B 1 235 ? 23.206  16.037  104.821 1.00 36.77  ? 254 GLU B CA  1 
ATOM   4578  C C   . GLU B 1 235 ? 24.338  17.022  105.060 1.00 37.41  ? 254 GLU B C   1 
ATOM   4579  O O   . GLU B 1 235 ? 24.348  17.700  106.084 1.00 36.86  ? 254 GLU B O   1 
ATOM   4580  C CB  . GLU B 1 235 ? 23.557  14.664  105.435 1.00 37.93  ? 254 GLU B CB  1 
ATOM   4581  C CG  . GLU B 1 235 ? 23.409  14.600  106.953 1.00 37.87  ? 254 GLU B CG  1 
ATOM   4582  C CD  . GLU B 1 235 ? 24.557  13.905  107.696 1.00 38.93  ? 254 GLU B CD  1 
ATOM   4583  O OE1 . GLU B 1 235 ? 25.030  12.807  107.276 1.00 39.03  ? 254 GLU B OE1 1 
ATOM   4584  O OE2 . GLU B 1 235 ? 24.967  14.428  108.751 1.00 39.73  ? 254 GLU B OE2 1 
ATOM   4585  N N   . HIS B 1 236 ? 25.276  17.120  104.127 1.00 35.53  ? 255 HIS B N   1 
ATOM   4586  C CA  . HIS B 1 236 ? 26.520  17.813  104.355 1.00 36.49  ? 255 HIS B CA  1 
ATOM   4587  C C   . HIS B 1 236 ? 26.607  19.158  103.638 1.00 35.09  ? 255 HIS B C   1 
ATOM   4588  O O   . HIS B 1 236 ? 27.708  19.654  103.413 1.00 36.27  ? 255 HIS B O   1 
ATOM   4589  C CB  . HIS B 1 236 ? 27.674  16.915  103.912 1.00 38.46  ? 255 HIS B CB  1 
ATOM   4590  C CG  . HIS B 1 236 ? 28.023  15.850  104.897 1.00 39.68  ? 255 HIS B CG  1 
ATOM   4591  N ND1 . HIS B 1 236 ? 29.195  15.131  104.833 1.00 40.56  ? 255 HIS B ND1 1 
ATOM   4592  C CD2 . HIS B 1 236 ? 27.347  15.390  105.976 1.00 39.20  ? 255 HIS B CD2 1 
ATOM   4593  C CE1 . HIS B 1 236 ? 29.212  14.261  105.826 1.00 40.79  ? 255 HIS B CE1 1 
ATOM   4594  N NE2 . HIS B 1 236 ? 28.102  14.404  106.535 1.00 40.26  ? 255 HIS B NE2 1 
ATOM   4595  N N   . PHE B 1 237 ? 25.497  19.800  103.327 1.00 40.43  ? 256 PHE B N   1 
ATOM   4596  C CA  . PHE B 1 237 ? 25.602  20.952  102.443 1.00 38.93  ? 256 PHE B CA  1 
ATOM   4597  C C   . PHE B 1 237 ? 26.534  22.052  102.987 1.00 39.35  ? 256 PHE B C   1 
ATOM   4598  O O   . PHE B 1 237 ? 26.276  22.661  104.033 1.00 38.73  ? 256 PHE B O   1 
ATOM   4599  C CB  . PHE B 1 237 ? 24.241  21.567  102.148 1.00 36.62  ? 256 PHE B CB  1 
ATOM   4600  C CG  . PHE B 1 237 ? 24.347  22.675  101.163 1.00 35.83  ? 256 PHE B CG  1 
ATOM   4601  C CD1 . PHE B 1 237 ? 24.694  22.395  99.845  1.00 36.71  ? 256 PHE B CD1 1 
ATOM   4602  C CD2 . PHE B 1 237 ? 24.234  23.993  101.548 1.00 34.76  ? 256 PHE B CD2 1 
ATOM   4603  C CE1 . PHE B 1 237 ? 24.861  23.398  98.935  1.00 36.23  ? 256 PHE B CE1 1 
ATOM   4604  C CE2 . PHE B 1 237 ? 24.418  24.967  100.637 1.00 34.56  ? 256 PHE B CE2 1 
ATOM   4605  C CZ  . PHE B 1 237 ? 24.723  24.662  99.327  1.00 35.16  ? 256 PHE B CZ  1 
ATOM   4606  N N   . GLY B 1 238 ? 27.600  22.325  102.241 1.00 37.97  ? 257 GLY B N   1 
ATOM   4607  C CA  . GLY B 1 238 ? 28.476  23.424  102.564 1.00 38.28  ? 257 GLY B CA  1 
ATOM   4608  C C   . GLY B 1 238 ? 29.459  23.195  103.687 1.00 40.36  ? 257 GLY B C   1 
ATOM   4609  O O   . GLY B 1 238 ? 30.129  24.144  104.110 1.00 41.04  ? 257 GLY B O   1 
ATOM   4610  N N   . HIS B 1 239 ? 29.583  21.978  104.177 1.00 38.31  ? 258 HIS B N   1 
ATOM   4611  C CA  . HIS B 1 239 ? 30.448  21.689  105.307 1.00 40.61  ? 258 HIS B CA  1 
ATOM   4612  C C   . HIS B 1 239 ? 31.061  20.312  105.114 1.00 42.54  ? 258 HIS B C   1 
ATOM   4613  O O   . HIS B 1 239 ? 30.767  19.614  104.139 1.00 42.56  ? 258 HIS B O   1 
ATOM   4614  C CB  . HIS B 1 239 ? 29.677  21.701  106.626 1.00 40.12  ? 258 HIS B CB  1 
ATOM   4615  C CG  . HIS B 1 239 ? 29.288  23.065  107.072 1.00 38.35  ? 258 HIS B CG  1 
ATOM   4616  N ND1 . HIS B 1 239 ? 28.357  23.836  106.406 1.00 36.34  ? 258 HIS B ND1 1 
ATOM   4617  C CD2 . HIS B 1 239 ? 29.724  23.809  108.110 1.00 38.86  ? 258 HIS B CD2 1 
ATOM   4618  C CE1 . HIS B 1 239 ? 28.238  24.996  107.021 1.00 35.08  ? 258 HIS B CE1 1 
ATOM   4619  N NE2 . HIS B 1 239 ? 29.061  25.003  108.052 1.00 36.84  ? 258 HIS B NE2 1 
ATOM   4620  N N   . PHE B 1 240 ? 31.876  19.902  106.086 1.00 39.67  ? 259 PHE B N   1 
ATOM   4621  C CA  . PHE B 1 240 ? 32.585  18.637  106.042 1.00 40.77  ? 259 PHE B CA  1 
ATOM   4622  C C   . PHE B 1 240 ? 33.432  18.645  104.779 1.00 41.85  ? 259 PHE B C   1 
ATOM   4623  O O   . PHE B 1 240 ? 34.254  19.569  104.635 1.00 43.12  ? 259 PHE B O   1 
ATOM   4624  C CB  . PHE B 1 240 ? 31.566  17.517  106.166 1.00 40.34  ? 259 PHE B CB  1 
ATOM   4625  C CG  . PHE B 1 240 ? 30.676  17.616  107.367 1.00 39.55  ? 259 PHE B CG  1 
ATOM   4626  C CD1 . PHE B 1 240 ? 31.090  17.147  108.590 1.00 40.19  ? 259 PHE B CD1 1 
ATOM   4627  C CD2 . PHE B 1 240 ? 29.410  18.147  107.261 1.00 37.82  ? 259 PHE B CD2 1 
ATOM   4628  C CE1 . PHE B 1 240 ? 30.266  17.208  109.685 1.00 38.96  ? 259 PHE B CE1 1 
ATOM   4629  C CE2 . PHE B 1 240 ? 28.586  18.213  108.350 1.00 36.55  ? 259 PHE B CE2 1 
ATOM   4630  C CZ  . PHE B 1 240 ? 29.005  17.738  109.558 1.00 37.18  ? 259 PHE B CZ  1 
ATOM   4631  N N   . GLN B 1 241 ? 33.285  17.677  103.866 1.00 44.76  ? 260 GLN B N   1 
ATOM   4632  C CA  . GLN B 1 241 ? 34.002  17.677  102.598 1.00 45.60  ? 260 GLN B CA  1 
ATOM   4633  C C   . GLN B 1 241 ? 33.187  18.251  101.436 1.00 43.72  ? 260 GLN B C   1 
ATOM   4634  O O   . GLN B 1 241 ? 33.608  18.131  100.277 1.00 43.66  ? 260 GLN B O   1 
ATOM   4635  C CB  . GLN B 1 241 ? 34.455  16.251  102.273 1.00 47.16  ? 260 GLN B CB  1 
ATOM   4636  C CG  . GLN B 1 241 ? 35.718  15.835  103.042 1.00 50.13  ? 260 GLN B CG  1 
ATOM   4637  C CD  . GLN B 1 241 ? 35.418  15.601  104.505 1.00 51.78  ? 260 GLN B CD  1 
ATOM   4638  O OE1 . GLN B 1 241 ? 35.776  16.426  105.385 1.00 52.94  ? 260 GLN B OE1 1 
ATOM   4639  N NE2 . GLN B 1 241 ? 34.721  14.472  104.789 1.00 51.81  ? 260 GLN B NE2 1 
ATOM   4640  N N   . SER B 1 242 ? 32.058  18.887  101.710 1.00 44.10  ? 261 SER B N   1 
ATOM   4641  C CA  . SER B 1 242 ? 31.184  19.368  100.652 1.00 42.09  ? 261 SER B CA  1 
ATOM   4642  C C   . SER B 1 242 ? 31.107  20.892  100.592 1.00 41.09  ? 261 SER B C   1 
ATOM   4643  O O   . SER B 1 242 ? 30.180  21.430  99.985  1.00 39.62  ? 261 SER B O   1 
ATOM   4644  C CB  . SER B 1 242 ? 29.771  18.812  100.822 1.00 40.88  ? 261 SER B CB  1 
ATOM   4645  O OG  . SER B 1 242 ? 29.771  17.410  100.868 1.00 41.43  ? 261 SER B OG  1 
ATOM   4646  N N   . ALA B 1 243 ? 32.074  21.586  101.184 1.00 43.00  ? 262 ALA B N   1 
ATOM   4647  C CA  . ALA B 1 243 ? 31.998  23.038  101.330 1.00 42.18  ? 262 ALA B CA  1 
ATOM   4648  C C   . ALA B 1 243 ? 32.577  23.805  100.149 1.00 42.28  ? 262 ALA B C   1 
ATOM   4649  O O   . ALA B 1 243 ? 32.442  25.028  100.094 1.00 41.48  ? 262 ALA B O   1 
ATOM   4650  C CB  . ALA B 1 243 ? 32.714  23.489  102.612 1.00 43.71  ? 262 ALA B CB  1 
ATOM   4651  N N   . SER B 1 244 ? 33.189  23.132  99.197  1.00 45.05  ? 263 SER B N   1 
ATOM   4652  C CA  . SER B 1 244 ? 33.757  23.823  98.054  1.00 45.36  ? 263 SER B CA  1 
ATOM   4653  C C   . SER B 1 244 ? 32.655  24.247  97.083  1.00 43.60  ? 263 SER B C   1 
ATOM   4654  O O   . SER B 1 244 ? 31.539  23.696  97.065  1.00 42.47  ? 263 SER B O   1 
ATOM   4655  C CB  . SER B 1 244 ? 34.768  22.927  97.335  1.00 47.18  ? 263 SER B CB  1 
ATOM   4656  O OG  . SER B 1 244 ? 34.129  21.822  96.710  1.00 46.78  ? 263 SER B OG  1 
ATOM   4657  N N   . LYS B 1 245 ? 32.972  25.265  96.277  1.00 44.83  ? 264 LYS B N   1 
ATOM   4658  C CA  . LYS B 1 245 ? 32.007  25.723  95.278  1.00 45.51  ? 264 LYS B CA  1 
ATOM   4659  C C   . LYS B 1 245 ? 31.652  24.572  94.337  1.00 44.94  ? 264 LYS B C   1 
ATOM   4660  O O   . LYS B 1 245 ? 30.484  24.387  93.987  1.00 44.27  ? 264 LYS B O   1 
ATOM   4661  C CB  . LYS B 1 245 ? 32.552  26.945  94.508  1.00 48.04  ? 264 LYS B CB  1 
ATOM   4662  C CG  . LYS B 1 245 ? 33.728  26.675  93.580  1.00 49.56  ? 264 LYS B CG  1 
ATOM   4663  C CD  . LYS B 1 245 ? 34.258  27.986  93.007  1.00 51.54  ? 264 LYS B CD  1 
ATOM   4664  C CE  . LYS B 1 245 ? 35.460  27.790  92.067  1.00 53.30  ? 264 LYS B CE  1 
ATOM   4665  N NZ  . LYS B 1 245 ? 36.767  27.599  92.800  1.00 53.88  ? 264 LYS B NZ  1 
ATOM   4666  N N   . GLU B 1 246 ? 32.646  23.768  93.942  1.00 46.33  ? 265 GLU B N   1 
ATOM   4667  C CA  . GLU B 1 246 ? 32.361  22.632  93.062  1.00 46.15  ? 265 GLU B CA  1 
ATOM   4668  C C   . GLU B 1 246 ? 31.296  21.733  93.674  1.00 43.90  ? 265 GLU B C   1 
ATOM   4669  O O   . GLU B 1 246 ? 30.298  21.402  93.017  1.00 43.57  ? 265 GLU B O   1 
ATOM   4670  C CB  . GLU B 1 246 ? 33.624  21.832  92.760  1.00 47.05  ? 265 GLU B CB  1 
ATOM   4671  C CG  . GLU B 1 246 ? 34.655  22.573  91.917  1.00 49.30  ? 265 GLU B CG  1 
ATOM   4672  C CD  . GLU B 1 246 ? 35.596  23.454  92.734  1.00 50.30  ? 265 GLU B CD  1 
ATOM   4673  O OE1 . GLU B 1 246 ? 35.487  23.454  93.997  1.00 49.07  ? 265 GLU B OE1 1 
ATOM   4674  O OE2 . GLU B 1 246 ? 36.449  24.147  92.111  1.00 52.47  ? 265 GLU B OE2 1 
ATOM   4675  N N   . THR B 1 247 ? 31.475  21.354  94.952  1.00 44.12  ? 266 THR B N   1 
ATOM   4676  C CA  . THR B 1 247 ? 30.540  20.414  95.560  1.00 42.25  ? 266 THR B CA  1 
ATOM   4677  C C   . THR B 1 247 ? 29.207  21.071  95.884  1.00 41.27  ? 266 THR B C   1 
ATOM   4678  O O   . THR B 1 247 ? 28.161  20.420  95.811  1.00 40.27  ? 266 THR B O   1 
ATOM   4679  C CB  . THR B 1 247 ? 31.119  19.780  96.845  1.00 41.64  ? 266 THR B CB  1 
ATOM   4680  O OG1 . THR B 1 247 ? 31.532  20.804  97.775  1.00 41.90  ? 266 THR B OG1 1 
ATOM   4681  C CG2 . THR B 1 247 ? 32.282  18.872  96.518  1.00 42.28  ? 266 THR B CG2 1 
ATOM   4682  N N   . MET B 1 248 ? 29.220  22.342  96.283  1.00 41.47  ? 267 MET B N   1 
ATOM   4683  C CA  . MET B 1 248 ? 27.951  22.993  96.573  1.00 40.77  ? 267 MET B CA  1 
ATOM   4684  C C   . MET B 1 248 ? 27.067  23.063  95.333  1.00 41.50  ? 267 MET B C   1 
ATOM   4685  O O   . MET B 1 248 ? 25.858  22.804  95.408  1.00 40.45  ? 267 MET B O   1 
ATOM   4686  C CB  . MET B 1 248 ? 28.205  24.380  97.124  1.00 41.82  ? 267 MET B CB  1 
ATOM   4687  C CG  . MET B 1 248 ? 28.369  24.397  98.619  1.00 41.36  ? 267 MET B CG  1 
ATOM   4688  S SD  . MET B 1 248 ? 28.681  26.040  99.322  1.00 42.50  ? 267 MET B SD  1 
ATOM   4689  C CE  . MET B 1 248 ? 29.771  26.787  98.101  1.00 44.88  ? 267 MET B CE  1 
ATOM   4690  N N   . LEU B 1 249 ? 27.671  23.412  94.194  1.00 40.89  ? 268 LEU B N   1 
ATOM   4691  C CA  . LEU B 1 249 ? 26.924  23.507  92.917  1.00 41.71  ? 268 LEU B CA  1 
ATOM   4692  C C   . LEU B 1 249 ? 26.560  22.086  92.471  1.00 40.25  ? 268 LEU B C   1 
ATOM   4693  O O   . LEU B 1 249 ? 25.550  21.937  91.804  1.00 39.83  ? 268 LEU B O   1 
ATOM   4694  C CB  . LEU B 1 249 ? 27.746  24.242  91.858  1.00 43.71  ? 268 LEU B CB  1 
ATOM   4695  C CG  . LEU B 1 249 ? 27.048  24.496  90.517  1.00 44.50  ? 268 LEU B CG  1 
ATOM   4696  C CD1 . LEU B 1 249 ? 25.693  25.163  90.683  1.00 44.32  ? 268 LEU B CD1 1 
ATOM   4697  C CD2 . LEU B 1 249 ? 27.934  25.339  89.621  1.00 46.63  ? 268 LEU B CD2 1 
ATOM   4698  N N   . ARG B 1 250 ? 27.351  21.077  92.833  1.00 43.56  ? 269 ARG B N   1 
ATOM   4699  C CA  . ARG B 1 250 ? 27.001  19.669  92.511  1.00 42.34  ? 269 ARG B CA  1 
ATOM   4700  C C   . ARG B 1 250 ? 25.762  19.280  93.332  1.00 40.49  ? 269 ARG B C   1 
ATOM   4701  O O   . ARG B 1 250 ? 24.930  18.513  92.806  1.00 39.70  ? 269 ARG B O   1 
ATOM   4702  C CB  . ARG B 1 250 ? 28.186  18.743  92.797  1.00 42.53  ? 269 ARG B CB  1 
ATOM   4703  C CG  . ARG B 1 250 ? 28.001  17.320  92.290  1.00 41.95  ? 269 ARG B CG  1 
ATOM   4704  C CD  . ARG B 1 250 ? 29.206  16.441  92.574  1.00 42.75  ? 269 ARG B CD  1 
ATOM   4705  N NE  . ARG B 1 250 ? 30.457  17.068  92.135  1.00 44.92  ? 269 ARG B NE  1 
ATOM   4706  C CZ  . ARG B 1 250 ? 31.453  17.422  92.937  1.00 45.68  ? 269 ARG B CZ  1 
ATOM   4707  N NH1 . ARG B 1 250 ? 31.848  16.622  93.910  1.00 44.48  ? 269 ARG B NH1 1 
ATOM   4708  N NH2 . ARG B 1 250 ? 32.053  18.584  92.760  1.00 47.43  ? 269 ARG B NH2 1 
ATOM   4709  N N   . ASP B 1 251 ? 25.632  19.809  94.551  1.00 42.12  ? 270 ASP B N   1 
ATOM   4710  C CA  . ASP B 1 251 ? 24.510  19.457  95.465  1.00 40.17  ? 270 ASP B CA  1 
ATOM   4711  C C   . ASP B 1 251 ? 23.240  20.218  95.072  1.00 40.34  ? 270 ASP B C   1 
ATOM   4712  O O   . ASP B 1 251 ? 22.161  19.619  95.204  1.00 39.17  ? 270 ASP B O   1 
ATOM   4713  C CB  . ASP B 1 251 ? 24.890  19.722  96.916  1.00 39.64  ? 270 ASP B CB  1 
ATOM   4714  C CG  . ASP B 1 251 ? 25.484  18.553  97.691  1.00 38.76  ? 270 ASP B CG  1 
ATOM   4715  O OD1 . ASP B 1 251 ? 25.501  17.428  97.156  1.00 38.62  ? 270 ASP B OD1 1 
ATOM   4716  O OD2 . ASP B 1 251 ? 25.931  18.778  98.834  1.00 38.51  ? 270 ASP B OD2 1 
ATOM   4717  N N   . ILE B 1 252 ? 23.344  21.480  94.640  1.00 37.32  ? 271 ILE B N   1 
ATOM   4718  C CA  . ILE B 1 252 ? 22.182  22.287  94.266  1.00 37.84  ? 271 ILE B CA  1 
ATOM   4719  C C   . ILE B 1 252 ? 21.605  21.806  92.952  1.00 38.37  ? 271 ILE B C   1 
ATOM   4720  O O   . ILE B 1 252 ? 20.398  21.623  92.810  1.00 37.73  ? 271 ILE B O   1 
ATOM   4721  C CB  . ILE B 1 252 ? 22.575  23.770  94.165  1.00 39.63  ? 271 ILE B CB  1 
ATOM   4722  C CG1 . ILE B 1 252 ? 22.938  24.336  95.530  1.00 39.74  ? 271 ILE B CG1 1 
ATOM   4723  C CG2 . ILE B 1 252 ? 21.464  24.603  93.490  1.00 40.23  ? 271 ILE B CG2 1 
ATOM   4724  C CD1 . ILE B 1 252 ? 23.734  25.579  95.399  1.00 41.85  ? 271 ILE B CD1 1 
ATOM   4725  N N   . LEU B 1 253 ? 22.464  21.612  91.962  1.00 39.12  ? 272 LEU B N   1 
ATOM   4726  C CA  . LEU B 1 253 ? 22.019  21.006  90.706  1.00 39.17  ? 272 LEU B CA  1 
ATOM   4727  C C   . LEU B 1 253 ? 21.280  19.681  90.906  1.00 37.30  ? 272 LEU B C   1 
ATOM   4728  O O   . LEU B 1 253 ? 20.324  19.379  90.180  1.00 37.26  ? 272 LEU B O   1 
ATOM   4729  C CB  . LEU B 1 253 ? 23.215  20.779  89.778  1.00 40.71  ? 272 LEU B CB  1 
ATOM   4730  C CG  . LEU B 1 253 ? 23.902  22.085  89.381  1.00 42.78  ? 272 LEU B CG  1 
ATOM   4731  C CD1 . LEU B 1 253 ? 25.215  21.787  88.634  1.00 44.07  ? 272 LEU B CD1 1 
ATOM   4732  C CD2 . LEU B 1 253 ? 22.997  23.017  88.534  1.00 43.59  ? 272 LEU B CD2 1 
ATOM   4733  N N   . GLU B 1 254 ? 21.712  18.865  91.867  1.00 40.07  ? 273 GLU B N   1 
ATOM   4734  C CA  . GLU B 1 254 ? 21.059  17.569  92.013  1.00 38.61  ? 273 GLU B CA  1 
ATOM   4735  C C   . GLU B 1 254 ? 19.717  17.681  92.719  1.00 37.24  ? 273 GLU B C   1 
ATOM   4736  O O   . GLU B 1 254 ? 18.823  16.882  92.438  1.00 36.48  ? 273 GLU B O   1 
ATOM   4737  C CB  . GLU B 1 254 ? 21.948  16.595  92.790  1.00 38.11  ? 273 GLU B CB  1 
ATOM   4738  C CG  . GLU B 1 254 ? 21.343  15.255  93.008  1.00 36.69  ? 273 GLU B CG  1 
ATOM   4739  C CD  . GLU B 1 254 ? 21.067  14.530  91.703  1.00 37.57  ? 273 GLU B CD  1 
ATOM   4740  O OE1 . GLU B 1 254 ? 21.329  15.068  90.614  1.00 39.01  ? 273 GLU B OE1 1 
ATOM   4741  O OE2 . GLU B 1 254 ? 20.612  13.377  91.763  1.00 36.79  ? 273 GLU B OE2 1 
ATOM   4742  N N   . MET B 1 255 ? 19.577  18.619  93.669  1.00 36.59  ? 274 MET B N   1 
ATOM   4743  C CA  . MET B 1 255 ? 18.259  18.888  94.232  1.00 35.88  ? 274 MET B CA  1 
ATOM   4744  C C   . MET B 1 255 ? 17.313  19.318  93.137  1.00 36.59  ? 274 MET B C   1 
ATOM   4745  O O   . MET B 1 255 ? 16.145  18.906  93.104  1.00 36.06  ? 274 MET B O   1 
ATOM   4746  C CB  . MET B 1 255 ? 18.326  19.984  95.292  1.00 36.21  ? 274 MET B CB  1 
ATOM   4747  C CG  . MET B 1 255 ? 16.979  20.367  95.922  1.00 35.59  ? 274 MET B CG  1 
ATOM   4748  S SD  . MET B 1 255 ? 17.083  21.601  97.272  1.00 36.08  ? 274 MET B SD  1 
ATOM   4749  C CE  . MET B 1 255 ? 18.151  22.823  96.494  1.00 38.34  ? 274 MET B CE  1 
ATOM   4750  N N   . GLN B 1 256 ? 17.805  20.161  92.228  1.00 37.16  ? 275 GLN B N   1 
ATOM   4751  C CA  . GLN B 1 256 ? 16.946  20.707  91.185  1.00 38.39  ? 275 GLN B CA  1 
ATOM   4752  C C   . GLN B 1 256 ? 16.477  19.574  90.289  1.00 38.11  ? 275 GLN B C   1 
ATOM   4753  O O   . GLN B 1 256 ? 15.283  19.421  90.031  1.00 38.24  ? 275 GLN B O   1 
ATOM   4754  C CB  . GLN B 1 256 ? 17.684  21.798  90.392  1.00 40.62  ? 275 GLN B CB  1 
ATOM   4755  C CG  . GLN B 1 256 ? 16.912  22.306  89.204  1.00 41.66  ? 275 GLN B CG  1 
ATOM   4756  C CD  . GLN B 1 256 ? 17.608  23.445  88.474  1.00 43.91  ? 275 GLN B CD  1 
ATOM   4757  O OE1 . GLN B 1 256 ? 17.061  24.535  88.380  1.00 44.69  ? 275 GLN B OE1 1 
ATOM   4758  N NE2 . GLN B 1 256 ? 18.798  23.198  87.953  1.00 44.64  ? 275 GLN B NE2 1 
ATOM   4759  N N   . ARG B 1 257 ? 17.411  18.739  89.841  1.00 38.39  ? 276 ARG B N   1 
ATOM   4760  C CA  . ARG B 1 257 ? 17.061  17.637  88.948  1.00 38.42  ? 276 ARG B CA  1 
ATOM   4761  C C   . ARG B 1 257 ? 16.159  16.620  89.646  1.00 36.77  ? 276 ARG B C   1 
ATOM   4762  O O   . ARG B 1 257 ? 15.084  16.263  89.137  1.00 36.98  ? 276 ARG B O   1 
ATOM   4763  C CB  . ARG B 1 257 ? 18.343  16.971  88.459  1.00 39.32  ? 276 ARG B CB  1 
ATOM   4764  C CG  . ARG B 1 257 ? 18.145  15.925  87.403  1.00 39.64  ? 276 ARG B CG  1 
ATOM   4765  C CD  . ARG B 1 257 ? 19.369  15.032  87.306  1.00 39.78  ? 276 ARG B CD  1 
ATOM   4766  N NE  . ARG B 1 257 ? 19.489  14.200  88.495  1.00 38.43  ? 276 ARG B NE  1 
ATOM   4767  C CZ  . ARG B 1 257 ? 18.700  13.160  88.740  1.00 37.56  ? 276 ARG B CZ  1 
ATOM   4768  N NH1 . ARG B 1 257 ? 17.742  12.803  87.889  1.00 38.43  ? 276 ARG B NH1 1 
ATOM   4769  N NH2 . ARG B 1 257 ? 18.871  12.463  89.865  1.00 36.41  ? 276 ARG B NH2 1 
ATOM   4770  N N   . ALA B 1 258 ? 16.580  16.155  90.825  1.00 37.00  ? 277 ALA B N   1 
ATOM   4771  C CA  . ALA B 1 258 ? 15.849  15.091  91.491  1.00 35.46  ? 277 ALA B CA  1 
ATOM   4772  C C   . ALA B 1 258 ? 14.418  15.515  91.784  1.00 34.96  ? 277 ALA B C   1 
ATOM   4773  O O   . ALA B 1 258 ? 13.472  14.745  91.572  1.00 34.69  ? 277 ALA B O   1 
ATOM   4774  C CB  . ALA B 1 258 ? 16.585  14.687  92.777  1.00 34.22  ? 277 ALA B CB  1 
ATOM   4775  N N   . ALA B 1 259 ? 14.248  16.738  92.275  1.00 33.95  ? 278 ALA B N   1 
ATOM   4776  C CA  . ALA B 1 259 ? 12.923  17.245  92.626  1.00 34.36  ? 278 ALA B CA  1 
ATOM   4777  C C   . ALA B 1 259 ? 12.058  17.494  91.387  1.00 36.23  ? 278 ALA B C   1 
ATOM   4778  O O   . ALA B 1 259 ? 10.848  17.262  91.418  1.00 36.78  ? 278 ALA B O   1 
ATOM   4779  C CB  . ALA B 1 259 ? 13.104  18.502  93.474  1.00 34.75  ? 278 ALA B CB  1 
ATOM   4780  N N   . LYS B 1 260 ? 12.661  17.909  90.283  1.00 35.35  ? 279 LYS B N   1 
ATOM   4781  C CA  . LYS B 1 260 ? 11.902  18.072  89.053  1.00 37.16  ? 279 LYS B CA  1 
ATOM   4782  C C   . LYS B 1 260 ? 11.456  16.729  88.509  1.00 37.12  ? 279 LYS B C   1 
ATOM   4783  O O   . LYS B 1 260 ? 10.488  16.670  87.744  1.00 38.69  ? 279 LYS B O   1 
ATOM   4784  C CB  . LYS B 1 260 ? 12.748  18.814  88.012  1.00 39.35  ? 279 LYS B CB  1 
ATOM   4785  C CG  . LYS B 1 260 ? 12.553  20.288  88.037  1.00 41.10  ? 279 LYS B CG  1 
ATOM   4786  C CD  . LYS B 1 260 ? 13.472  21.009  87.053  1.00 42.98  ? 279 LYS B CD  1 
ATOM   4787  C CE  . LYS B 1 260 ? 13.248  22.539  87.150  1.00 43.55  ? 279 LYS B CE  1 
ATOM   4788  N NZ  . LYS B 1 260 ? 14.131  23.266  86.197  1.00 45.95  ? 279 LYS B NZ  1 
ATOM   4789  N N   . ALA B 1 261 ? 12.139  15.651  88.911  1.00 36.71  ? 280 ALA B N   1 
ATOM   4790  C CA  . ALA B 1 261 ? 11.788  14.290  88.538  1.00 36.77  ? 280 ALA B CA  1 
ATOM   4791  C C   . ALA B 1 261 ? 10.753  13.688  89.463  1.00 35.77  ? 280 ALA B C   1 
ATOM   4792  O O   . ALA B 1 261 ? 10.305  12.581  89.200  1.00 36.53  ? 280 ALA B O   1 
ATOM   4793  C CB  . ALA B 1 261 ? 13.033  13.416  88.507  1.00 36.65  ? 280 ALA B CB  1 
ATOM   4794  N N   . GLY B 1 262 ? 10.358  14.385  90.524  1.00 35.62  ? 281 GLY B N   1 
ATOM   4795  C CA  . GLY B 1 262 ? 9.236   13.984  91.340  1.00 34.73  ? 281 GLY B CA  1 
ATOM   4796  C C   . GLY B 1 262 ? 9.612   13.557  92.728  1.00 32.63  ? 281 GLY B C   1 
ATOM   4797  O O   . GLY B 1 262 ? 8.732   13.127  93.483  1.00 32.62  ? 281 GLY B O   1 
ATOM   4798  N N   . LYS B 1 263 ? 10.884  13.648  93.096  1.00 35.09  ? 282 LYS B N   1 
ATOM   4799  C CA  . LYS B 1 263 ? 11.340  13.134  94.374  1.00 33.23  ? 282 LYS B CA  1 
ATOM   4800  C C   . LYS B 1 263 ? 11.298  14.236  95.404  1.00 32.92  ? 282 LYS B C   1 
ATOM   4801  O O   . LYS B 1 263 ? 11.301  15.413  95.078  1.00 34.19  ? 282 LYS B O   1 
ATOM   4802  C CB  . LYS B 1 263 ? 12.763  12.604  94.276  1.00 32.90  ? 282 LYS B CB  1 
ATOM   4803  C CG  . LYS B 1 263 ? 12.935  11.392  93.366  1.00 33.87  ? 282 LYS B CG  1 
ATOM   4804  C CD  . LYS B 1 263 ? 11.944  10.306  93.738  1.00 33.13  ? 282 LYS B CD  1 
ATOM   4805  C CE  . LYS B 1 263 ? 12.274  8.977   93.075  1.00 33.40  ? 282 LYS B CE  1 
ATOM   4806  N NZ  . LYS B 1 263 ? 11.163  8.000   93.261  1.00 33.34  ? 282 LYS B NZ  1 
ATOM   4807  N N   . ILE B 1 264 ? 11.249  13.843  96.664  1.00 32.41  ? 283 ILE B N   1 
ATOM   4808  C CA  . ILE B 1 264 ? 11.477  14.788  97.743  1.00 31.86  ? 283 ILE B CA  1 
ATOM   4809  C C   . ILE B 1 264 ? 12.972  14.936  97.937  1.00 31.38  ? 283 ILE B C   1 
ATOM   4810  O O   . ILE B 1 264 ? 13.734  13.962  97.798  1.00 31.22  ? 283 ILE B O   1 
ATOM   4811  C CB  . ILE B 1 264 ? 10.821  14.325  99.052  1.00 30.77  ? 283 ILE B CB  1 
ATOM   4812  C CG1 . ILE B 1 264 ? 9.312   14.273  98.905  1.00 31.49  ? 283 ILE B CG1 1 
ATOM   4813  C CG2 . ILE B 1 264 ? 11.288  15.268  100.177 1.00 30.55  ? 283 ILE B CG2 1 
ATOM   4814  C CD1 . ILE B 1 264 ? 8.626   13.519  99.980  1.00 30.79  ? 283 ILE B CD1 1 
ATOM   4815  N N   . VAL B 1 265 ? 13.400  16.157  98.250  1.00 30.64  ? 284 VAL B N   1 
ATOM   4816  C CA  . VAL B 1 265 ? 14.783  16.441  98.587  1.00 30.89  ? 284 VAL B CA  1 
ATOM   4817  C C   . VAL B 1 265 ? 14.795  17.273  99.852  1.00 30.75  ? 284 VAL B C   1 
ATOM   4818  O O   . VAL B 1 265 ? 14.002  18.211  100.001 1.00 31.22  ? 284 VAL B O   1 
ATOM   4819  C CB  . VAL B 1 265 ? 15.545  17.176  97.481  1.00 33.08  ? 284 VAL B CB  1 
ATOM   4820  C CG1 . VAL B 1 265 ? 16.954  17.389  97.926  1.00 33.38  ? 284 VAL B CG1 1 
ATOM   4821  C CG2 . VAL B 1 265 ? 15.525  16.400  96.202  1.00 33.81  ? 284 VAL B CG2 1 
ATOM   4822  N N   . VAL B 1 266 ? 15.678  16.920  100.766 1.00 31.47  ? 285 VAL B N   1 
ATOM   4823  C CA  . VAL B 1 266 ? 15.806  17.623  102.026 1.00 31.16  ? 285 VAL B CA  1 
ATOM   4824  C C   . VAL B 1 266 ? 17.235  18.090  102.118 1.00 31.92  ? 285 VAL B C   1 
ATOM   4825  O O   . VAL B 1 266 ? 18.155  17.267  102.110 1.00 31.83  ? 285 VAL B O   1 
ATOM   4826  C CB  . VAL B 1 266 ? 15.444  16.736  103.213 1.00 29.90  ? 285 VAL B CB  1 
ATOM   4827  C CG1 . VAL B 1 266 ? 15.792  17.455  104.482 1.00 30.01  ? 285 VAL B CG1 1 
ATOM   4828  C CG2 . VAL B 1 266 ? 13.963  16.411  103.153 1.00 29.48  ? 285 VAL B CG2 1 
ATOM   4829  N N   . LEU B 1 267 ? 17.428  19.398  102.179 1.00 31.34  ? 286 LEU B N   1 
ATOM   4830  C CA  . LEU B 1 267 ? 18.768  19.974  102.225 1.00 32.31  ? 286 LEU B CA  1 
ATOM   4831  C C   . LEU B 1 267 ? 19.088  20.422  103.659 1.00 31.74  ? 286 LEU B C   1 
ATOM   4832  O O   . LEU B 1 267 ? 18.324  21.176  104.288 1.00 31.62  ? 286 LEU B O   1 
ATOM   4833  C CB  . LEU B 1 267 ? 18.892  21.108  101.211 1.00 34.21  ? 286 LEU B CB  1 
ATOM   4834  C CG  . LEU B 1 267 ? 20.321  21.531  100.893 1.00 35.83  ? 286 LEU B CG  1 
ATOM   4835  C CD1 . LEU B 1 267 ? 20.542  22.023  99.496  1.00 38.38  ? 286 LEU B CD1 1 
ATOM   4836  C CD2 . LEU B 1 267 ? 20.643  22.622  101.905 1.00 36.22  ? 286 LEU B CD2 1 
ATOM   4837  N N   . LYS B 1 268 ? 20.195  19.918  104.196 1.00 33.80  ? 287 LYS B N   1 
ATOM   4838  C CA  . LYS B 1 268 ? 20.544  20.188  105.581 1.00 33.76  ? 287 LYS B CA  1 
ATOM   4839  C C   . LYS B 1 268 ? 21.546  21.332  105.586 1.00 35.66  ? 287 LYS B C   1 
ATOM   4840  O O   . LYS B 1 268 ? 22.696  21.177  105.171 1.00 36.76  ? 287 LYS B O   1 
ATOM   4841  C CB  . LYS B 1 268 ? 21.063  18.928  106.276 1.00 33.37  ? 287 LYS B CB  1 
ATOM   4842  C CG  . LYS B 1 268 ? 21.584  19.154  107.692 1.00 35.35  ? 287 LYS B CG  1 
ATOM   4843  C CD  . LYS B 1 268 ? 20.523  19.616  108.666 1.00 34.14  ? 287 LYS B CD  1 
ATOM   4844  C CE  . LYS B 1 268 ? 21.089  19.438  110.077 1.00 35.89  ? 287 LYS B CE  1 
ATOM   4845  N NZ  . LYS B 1 268 ? 22.003  20.585  110.338 1.00 35.68  ? 287 LYS B NZ  1 
ATOM   4846  N N   . GLY B 1 269 ? 21.078  22.510  105.996 1.00 34.05  ? 288 GLY B N   1 
ATOM   4847  C CA  . GLY B 1 269 ? 21.944  23.648  106.152 1.00 35.29  ? 288 GLY B CA  1 
ATOM   4848  C C   . GLY B 1 269 ? 22.513  23.657  107.562 1.00 35.34  ? 288 GLY B C   1 
ATOM   4849  O O   . GLY B 1 269 ? 21.800  23.388  108.533 1.00 34.64  ? 288 GLY B O   1 
ATOM   4850  N N   . TRP B 1 270 ? 23.786  23.979  107.659 1.00 36.29  ? 289 TRP B N   1 
ATOM   4851  C CA  . TRP B 1 270 ? 24.435  24.063  108.959 1.00 36.98  ? 289 TRP B CA  1 
ATOM   4852  C C   . TRP B 1 270 ? 24.635  25.509  109.383 1.00 38.43  ? 289 TRP B C   1 
ATOM   4853  O O   . TRP B 1 270 ? 25.121  26.343  108.614 1.00 40.08  ? 289 TRP B O   1 
ATOM   4854  C CB  . TRP B 1 270 ? 25.740  23.305  108.887 1.00 37.79  ? 289 TRP B CB  1 
ATOM   4855  C CG  . TRP B 1 270 ? 25.478  21.866  108.647 1.00 36.08  ? 289 TRP B CG  1 
ATOM   4856  C CD1 . TRP B 1 270 ? 25.371  21.240  107.446 1.00 35.35  ? 289 TRP B CD1 1 
ATOM   4857  C CD2 . TRP B 1 270 ? 25.256  20.872  109.645 1.00 35.22  ? 289 TRP B CD2 1 
ATOM   4858  N NE1 . TRP B 1 270 ? 25.101  19.920  107.627 1.00 34.40  ? 289 TRP B NE1 1 
ATOM   4859  C CE2 . TRP B 1 270 ? 25.029  19.658  108.971 1.00 34.37  ? 289 TRP B CE2 1 
ATOM   4860  C CE3 . TRP B 1 270 ? 25.218  20.891  111.046 1.00 35.90  ? 289 TRP B CE3 1 
ATOM   4861  C CZ2 . TRP B 1 270 ? 24.801  18.446  109.649 1.00 33.94  ? 289 TRP B CZ2 1 
ATOM   4862  C CZ3 . TRP B 1 270 ? 24.988  19.681  111.721 1.00 35.58  ? 289 TRP B CZ3 1 
ATOM   4863  C CH2 . TRP B 1 270 ? 24.780  18.477  111.012 1.00 34.58  ? 289 TRP B CH2 1 
ATOM   4864  N N   . ALA B 1 271 ? 24.246  25.787  110.622 1.00 33.60  ? 290 ALA B N   1 
ATOM   4865  C CA  . ALA B 1 271 ? 24.230  27.123  111.172 1.00 35.24  ? 290 ALA B CA  1 
ATOM   4866  C C   . ALA B 1 271 ? 25.608  27.633  111.531 1.00 37.03  ? 290 ALA B C   1 
ATOM   4867  O O   . ALA B 1 271 ? 25.782  28.207  112.601 1.00 38.17  ? 290 ALA B O   1 
ATOM   4868  C CB  . ALA B 1 271 ? 23.349  27.145  112.415 1.00 35.35  ? 290 ALA B CB  1 
ATOM   4869  N N   . GLY B 1 272 ? 26.578  27.491  110.636 1.00 35.86  ? 291 GLY B N   1 
ATOM   4870  C CA  . GLY B 1 272 ? 27.877  28.119  110.823 1.00 37.54  ? 291 GLY B CA  1 
ATOM   4871  C C   . GLY B 1 272 ? 28.875  27.274  111.584 1.00 37.58  ? 291 GLY B C   1 
ATOM   4872  O O   . GLY B 1 272 ? 30.037  27.670  111.734 1.00 39.26  ? 291 GLY B O   1 
ATOM   4873  N N   . PHE B 1 273 ? 28.467  26.117  112.065 1.00 37.14  ? 292 PHE B N   1 
ATOM   4874  C CA  . PHE B 1 273 ? 29.356  25.224  112.787 1.00 37.03  ? 292 PHE B CA  1 
ATOM   4875  C C   . PHE B 1 273 ? 28.534  23.960  112.945 1.00 35.44  ? 292 PHE B C   1 
ATOM   4876  O O   . PHE B 1 273 ? 27.315  23.966  112.716 1.00 34.46  ? 292 PHE B O   1 
ATOM   4877  C CB  . PHE B 1 273 ? 29.822  25.810  114.117 1.00 38.31  ? 292 PHE B CB  1 
ATOM   4878  C CG  . PHE B 1 273 ? 28.717  26.057  115.065 1.00 38.27  ? 292 PHE B CG  1 
ATOM   4879  C CD1 . PHE B 1 273 ? 27.923  27.161  114.924 1.00 38.72  ? 292 PHE B CD1 1 
ATOM   4880  C CD2 . PHE B 1 273 ? 28.448  25.158  116.086 1.00 37.92  ? 292 PHE B CD2 1 
ATOM   4881  C CE1 . PHE B 1 273 ? 26.887  27.375  115.786 1.00 39.25  ? 292 PHE B CE1 1 
ATOM   4882  C CE2 . PHE B 1 273 ? 27.396  25.368  116.963 1.00 38.36  ? 292 PHE B CE2 1 
ATOM   4883  C CZ  . PHE B 1 273 ? 26.620  26.473  116.811 1.00 39.07  ? 292 PHE B CZ  1 
ATOM   4884  N N   . THR B 1 274 ? 29.208  22.877  113.291 1.00 38.45  ? 293 THR B N   1 
ATOM   4885  C CA  . THR B 1 274 ? 28.541  21.593  113.410 1.00 37.34  ? 293 THR B CA  1 
ATOM   4886  C C   . THR B 1 274 ? 28.762  21.048  114.803 1.00 37.72  ? 293 THR B C   1 
ATOM   4887  O O   . THR B 1 274 ? 29.619  21.508  115.568 1.00 38.83  ? 293 THR B O   1 
ATOM   4888  C CB  . THR B 1 274 ? 29.041  20.572  112.369 1.00 36.77  ? 293 THR B CB  1 
ATOM   4889  O OG1 . THR B 1 274 ? 30.386  20.159  112.694 1.00 37.47  ? 293 THR B OG1 1 
ATOM   4890  C CG2 . THR B 1 274 ? 28.949  21.185  110.942 1.00 36.75  ? 293 THR B CG2 1 
ATOM   4891  N N   . PHE B 1 275 ? 27.979  20.024  115.112 1.00 37.33  ? 294 PHE B N   1 
ATOM   4892  C CA  . PHE B 1 275 ? 28.085  19.358  116.403 1.00 37.93  ? 294 PHE B CA  1 
ATOM   4893  C C   . PHE B 1 275 ? 29.421  18.676  116.607 1.00 38.34  ? 294 PHE B C   1 
ATOM   4894  O O   . PHE B 1 275 ? 29.673  18.233  117.722 1.00 39.56  ? 294 PHE B O   1 
ATOM   4895  C CB  . PHE B 1 275 ? 26.943  18.367  116.533 1.00 37.41  ? 294 PHE B CB  1 
ATOM   4896  C CG  . PHE B 1 275 ? 27.050  17.224  115.619 1.00 36.48  ? 294 PHE B CG  1 
ATOM   4897  C CD1 . PHE B 1 275 ? 26.598  17.315  114.329 1.00 35.50  ? 294 PHE B CD1 1 
ATOM   4898  C CD2 . PHE B 1 275 ? 27.588  16.031  116.051 1.00 37.39  ? 294 PHE B CD2 1 
ATOM   4899  C CE1 . PHE B 1 275 ? 26.684  16.240  113.484 1.00 34.78  ? 294 PHE B CE1 1 
ATOM   4900  C CE2 . PHE B 1 275 ? 27.680  14.973  115.212 1.00 36.77  ? 294 PHE B CE2 1 
ATOM   4901  C CZ  . PHE B 1 275 ? 27.229  15.082  113.924 1.00 35.48  ? 294 PHE B CZ  1 
ATOM   4902  N N   . ILE B 1 276 ? 30.289  18.625  115.592 1.00 38.97  ? 295 ILE B N   1 
ATOM   4903  C CA  . ILE B 1 276 ? 31.599  17.993  115.731 1.00 39.75  ? 295 ILE B CA  1 
ATOM   4904  C C   . ILE B 1 276 ? 32.752  18.980  115.874 1.00 40.83  ? 295 ILE B C   1 
ATOM   4905  O O   . ILE B 1 276 ? 33.897  18.543  116.069 1.00 41.94  ? 295 ILE B O   1 
ATOM   4906  C CB  . ILE B 1 276 ? 31.910  17.036  114.552 1.00 39.42  ? 295 ILE B CB  1 
ATOM   4907  C CG1 . ILE B 1 276 ? 32.078  17.755  113.210 1.00 39.24  ? 295 ILE B CG1 1 
ATOM   4908  C CG2 . ILE B 1 276 ? 30.784  16.016  114.341 1.00 38.30  ? 295 ILE B CG2 1 
ATOM   4909  C CD1 . ILE B 1 276 ? 32.632  16.890  112.107 1.00 39.17  ? 295 ILE B CD1 1 
ATOM   4910  N N   . ASP B 1 277 ? 32.501  20.285  115.766 1.00 40.55  ? 296 ASP B N   1 
ATOM   4911  C CA  . ASP B 1 277 ? 33.517  21.312  115.999 1.00 42.10  ? 296 ASP B CA  1 
ATOM   4912  C C   . ASP B 1 277 ? 33.581  21.563  117.499 1.00 42.96  ? 296 ASP B C   1 
ATOM   4913  O O   . ASP B 1 277 ? 32.746  22.292  118.046 1.00 43.11  ? 296 ASP B O   1 
ATOM   4914  C CB  . ASP B 1 277 ? 33.176  22.604  115.246 1.00 42.34  ? 296 ASP B CB  1 
ATOM   4915  C CG  . ASP B 1 277 ? 32.953  22.360  113.754 1.00 41.40  ? 296 ASP B CG  1 
ATOM   4916  O OD1 . ASP B 1 277 ? 33.664  21.460  113.227 1.00 41.42  ? 296 ASP B OD1 1 
ATOM   4917  O OD2 . ASP B 1 277 ? 32.079  23.005  113.124 1.00 41.01  ? 296 ASP B OD2 1 
ATOM   4918  N N   . ASP B 1 278 ? 34.590  20.985  118.164 1.00 43.09  ? 297 ASP B N   1 
ATOM   4919  C CA  . ASP B 1 278 ? 34.647  21.029  119.622 1.00 44.12  ? 297 ASP B CA  1 
ATOM   4920  C C   . ASP B 1 278 ? 34.566  22.464  120.092 1.00 44.97  ? 297 ASP B C   1 
ATOM   4921  O O   . ASP B 1 278 ? 33.712  22.819  120.907 1.00 45.09  ? 297 ASP B O   1 
ATOM   4922  C CB  . ASP B 1 278 ? 35.921  20.363  120.147 1.00 45.63  ? 297 ASP B CB  1 
ATOM   4923  N N   . GLN B 1 279 ? 35.446  23.318  119.574 1.00 44.44  ? 298 GLN B N   1 
ATOM   4924  C CA  . GLN B 1 279 ? 35.513  24.690  120.072 1.00 45.49  ? 298 GLN B CA  1 
ATOM   4925  C C   . GLN B 1 279 ? 34.171  25.383  119.867 1.00 44.49  ? 298 GLN B C   1 
ATOM   4926  O O   . GLN B 1 279 ? 33.596  25.954  120.802 1.00 45.03  ? 298 GLN B O   1 
ATOM   4927  C CB  . GLN B 1 279 ? 36.635  25.443  119.369 1.00 46.75  ? 298 GLN B CB  1 
ATOM   4928  C CG  . GLN B 1 279 ? 38.079  25.301  119.940 1.00 48.60  ? 298 GLN B CG  1 
ATOM   4929  C CD  . GLN B 1 279 ? 38.166  24.911  121.430 1.00 50.22  ? 298 GLN B CD  1 
ATOM   4930  O OE1 . GLN B 1 279 ? 37.931  25.723  122.320 1.00 52.46  ? 298 GLN B OE1 1 
ATOM   4931  N NE2 . GLN B 1 279 ? 38.543  23.673  121.693 1.00 49.22  ? 298 GLN B NE2 1 
ATOM   4932  N N   . ALA B 1 280 ? 33.630  25.306  118.658 1.00 41.90  ? 299 ALA B N   1 
ATOM   4933  C CA  . ALA B 1 280 ? 32.352  25.956  118.407 1.00 41.42  ? 299 ALA B CA  1 
ATOM   4934  C C   . ALA B 1 280 ? 31.293  25.450  119.366 1.00 40.72  ? 299 ALA B C   1 
ATOM   4935  O O   . ALA B 1 280 ? 30.435  26.210  119.803 1.00 41.09  ? 299 ALA B O   1 
ATOM   4936  C CB  . ALA B 1 280 ? 31.908  25.737  116.962 1.00 40.19  ? 299 ALA B CB  1 
ATOM   4937  N N   . MET B 1 281 ? 31.321  24.160  119.695 1.00 41.61  ? 300 MET B N   1 
ATOM   4938  C CA  . MET B 1 281 ? 30.268  23.593  120.523 1.00 41.58  ? 300 MET B CA  1 
ATOM   4939  C C   . MET B 1 281 ? 30.409  23.980  121.982 1.00 42.55  ? 300 MET B C   1 
ATOM   4940  O O   . MET B 1 281 ? 29.425  23.891  122.730 1.00 43.01  ? 300 MET B O   1 
ATOM   4941  C CB  . MET B 1 281 ? 30.260  22.074  120.399 1.00 40.62  ? 300 MET B CB  1 
ATOM   4942  C CG  . MET B 1 281 ? 29.720  21.630  119.092 1.00 39.45  ? 300 MET B CG  1 
ATOM   4943  S SD  . MET B 1 281 ? 27.947  22.065  118.938 1.00 39.11  ? 300 MET B SD  1 
ATOM   4944  C CE  . MET B 1 281 ? 27.209  20.989  120.176 1.00 39.53  ? 300 MET B CE  1 
ATOM   4945  N N   . ARG B 1 282 ? 31.595  24.424  122.391 1.00 39.34  ? 301 ARG B N   1 
ATOM   4946  C CA  . ARG B 1 282 ? 31.839  24.823  123.771 1.00 40.93  ? 301 ARG B CA  1 
ATOM   4947  C C   . ARG B 1 282 ? 31.444  26.269  124.024 1.00 41.33  ? 301 ARG B C   1 
ATOM   4948  O O   . ARG B 1 282 ? 31.412  26.692  125.182 1.00 42.40  ? 301 ARG B O   1 
ATOM   4949  C CB  . ARG B 1 282 ? 33.308  24.548  124.138 1.00 43.12  ? 301 ARG B CB  1 
ATOM   4950  N N   . LYS B 1 283 ? 31.028  26.981  122.979 1.00 39.08  ? 302 LYS B N   1 
ATOM   4951  C CA  . LYS B 1 283 ? 30.609  28.373  123.084 1.00 39.54  ? 302 LYS B CA  1 
ATOM   4952  C C   . LYS B 1 283 ? 29.268  28.523  123.810 1.00 38.86  ? 302 LYS B C   1 
ATOM   4953  O O   . LYS B 1 283 ? 28.373  27.671  123.660 1.00 37.98  ? 302 LYS B O   1 
ATOM   4954  C CB  . LYS B 1 283 ? 30.428  28.977  121.693 1.00 39.70  ? 302 LYS B CB  1 
ATOM   4955  C CG  . LYS B 1 283 ? 31.649  29.197  120.833 1.00 41.30  ? 302 LYS B CG  1 
ATOM   4956  C CD  . LYS B 1 283 ? 32.826  29.638  121.594 1.00 43.44  ? 302 LYS B CD  1 
ATOM   4957  C CE  . LYS B 1 283 ? 33.847  30.159  120.608 1.00 44.92  ? 302 LYS B CE  1 
ATOM   4958  N NZ  . LYS B 1 283 ? 35.146  30.378  121.253 1.00 46.60  ? 302 LYS B NZ  1 
ATOM   4959  N N   . PRO B 1 284 ? 29.073  29.656  124.528 1.00 38.64  ? 303 PRO B N   1 
ATOM   4960  C CA  . PRO B 1 284 ? 27.784  29.914  125.176 1.00 38.26  ? 303 PRO B CA  1 
ATOM   4961  C C   . PRO B 1 284 ? 26.621  29.991  124.194 1.00 37.07  ? 303 PRO B C   1 
ATOM   4962  O O   . PRO B 1 284 ? 26.755  30.434  123.050 1.00 36.96  ? 303 PRO B O   1 
ATOM   4963  C CB  . PRO B 1 284 ? 28.004  31.271  125.864 1.00 39.43  ? 303 PRO B CB  1 
ATOM   4964  C CG  . PRO B 1 284 ? 29.435  31.326  126.110 1.00 40.84  ? 303 PRO B CG  1 
ATOM   4965  C CD  . PRO B 1 284 ? 30.048  30.715  124.876 1.00 39.99  ? 303 PRO B CD  1 
ATOM   4966  N N   . LEU B 1 285 ? 25.445  29.624  124.691 1.00 39.21  ? 304 LEU B N   1 
ATOM   4967  C CA  . LEU B 1 285 ? 24.292  29.501  123.817 1.00 38.16  ? 304 LEU B CA  1 
ATOM   4968  C C   . LEU B 1 285 ? 23.976  30.812  123.121 1.00 38.20  ? 304 LEU B C   1 
ATOM   4969  O O   . LEU B 1 285 ? 23.588  30.822  121.941 1.00 37.66  ? 304 LEU B O   1 
ATOM   4970  C CB  . LEU B 1 285 ? 23.095  29.005  124.625 1.00 37.53  ? 304 LEU B CB  1 
ATOM   4971  C CG  . LEU B 1 285 ? 21.789  28.819  123.859 1.00 36.51  ? 304 LEU B CG  1 
ATOM   4972  C CD1 . LEU B 1 285 ? 21.929  27.879  122.665 1.00 36.13  ? 304 LEU B CD1 1 
ATOM   4973  C CD2 . LEU B 1 285 ? 20.655  28.368  124.807 1.00 35.97  ? 304 LEU B CD2 1 
ATOM   4974  N N   . THR B 1 286 ? 24.131  31.940  123.814 1.00 37.55  ? 305 THR B N   1 
ATOM   4975  C CA  . THR B 1 286 ? 23.760  33.186  123.140 1.00 37.65  ? 305 THR B CA  1 
ATOM   4976  C C   . THR B 1 286 ? 24.741  33.503  122.003 1.00 37.88  ? 305 THR B C   1 
ATOM   4977  O O   . THR B 1 286 ? 24.347  34.045  120.974 1.00 38.16  ? 305 THR B O   1 
ATOM   4978  C CB  . THR B 1 286 ? 23.661  34.335  124.135 1.00 38.97  ? 305 THR B CB  1 
ATOM   4979  O OG1 . THR B 1 286 ? 24.918  34.991  124.161 1.00 40.29  ? 305 THR B OG1 1 
ATOM   4980  C CG2 . THR B 1 286 ? 23.282  33.864  125.546 1.00 39.36  ? 305 THR B CG2 1 
ATOM   4981  N N   . GLN B 1 287 ? 26.004  33.094  122.134 1.00 36.78  ? 306 GLN B N   1 
ATOM   4982  C CA  . GLN B 1 287 ? 26.926  33.167  121.001 1.00 37.21  ? 306 GLN B CA  1 
ATOM   4983  C C   . GLN B 1 287 ? 26.610  32.136  119.919 1.00 36.49  ? 306 GLN B C   1 
ATOM   4984  O O   . GLN B 1 287 ? 26.848  32.396  118.734 1.00 36.81  ? 306 GLN B O   1 
ATOM   4985  C CB  . GLN B 1 287 ? 28.338  32.971  121.528 1.00 38.56  ? 306 GLN B CB  1 
ATOM   4986  C CG  . GLN B 1 287 ? 29.462  33.026  120.534 1.00 39.66  ? 306 GLN B CG  1 
ATOM   4987  C CD  . GLN B 1 287 ? 30.774  32.921  121.249 1.00 41.36  ? 306 GLN B CD  1 
ATOM   4988  O OE1 . GLN B 1 287 ? 30.800  32.638  122.439 1.00 41.41  ? 306 GLN B OE1 1 
ATOM   4989  N NE2 . GLN B 1 287 ? 31.868  33.151  120.549 1.00 42.21  ? 306 GLN B NE2 1 
ATOM   4990  N N   . LYS B 1 288 ? 26.113  30.964  120.284 1.00 38.72  ? 307 LYS B N   1 
ATOM   4991  C CA  . LYS B 1 288 ? 25.797  30.007  119.241 1.00 38.01  ? 307 LYS B CA  1 
ATOM   4992  C C   . LYS B 1 288 ? 24.680  30.555  118.380 1.00 37.84  ? 307 LYS B C   1 
ATOM   4993  O O   . LYS B 1 288 ? 24.721  30.470  117.151 1.00 38.06  ? 307 LYS B O   1 
ATOM   4994  C CB  . LYS B 1 288 ? 25.395  28.658  119.837 1.00 37.08  ? 307 LYS B CB  1 
ATOM   4995  C CG  . LYS B 1 288 ? 26.537  27.796  120.411 1.00 37.47  ? 307 LYS B CG  1 
ATOM   4996  C CD  . LYS B 1 288 ? 26.049  26.382  120.596 1.00 36.97  ? 307 LYS B CD  1 
ATOM   4997  C CE  . LYS B 1 288 ? 27.117  25.445  121.046 1.00 37.33  ? 307 LYS B CE  1 
ATOM   4998  N NZ  . LYS B 1 288 ? 27.152  25.508  122.476 1.00 37.98  ? 307 LYS B NZ  1 
ATOM   4999  N N   . ARG B 1 289 ? 23.686  31.148  119.031 1.00 40.31  ? 308 ARG B N   1 
ATOM   5000  C CA  . ARG B 1 289 ? 22.557  31.722  118.323 1.00 39.70  ? 308 ARG B CA  1 
ATOM   5001  C C   . ARG B 1 289 ? 22.966  32.868  117.413 1.00 40.76  ? 308 ARG B C   1 
ATOM   5002  O O   . ARG B 1 289 ? 22.445  32.993  116.292 1.00 40.44  ? 308 ARG B O   1 
ATOM   5003  C CB  . ARG B 1 289 ? 21.544  32.229  119.330 1.00 39.28  ? 308 ARG B CB  1 
ATOM   5004  C CG  . ARG B 1 289 ? 20.881  31.142  120.071 1.00 39.03  ? 308 ARG B CG  1 
ATOM   5005  C CD  . ARG B 1 289 ? 19.974  31.758  121.063 1.00 39.07  ? 308 ARG B CD  1 
ATOM   5006  N NE  . ARG B 1 289 ? 19.059  30.749  121.520 1.00 38.34  ? 308 ARG B NE  1 
ATOM   5007  C CZ  . ARG B 1 289 ? 18.530  30.718  122.732 1.00 38.26  ? 308 ARG B CZ  1 
ATOM   5008  N NH1 . ARG B 1 289 ? 18.727  31.716  123.602 1.00 38.97  ? 308 ARG B NH1 1 
ATOM   5009  N NH2 . ARG B 1 289 ? 17.787  29.654  123.086 1.00 37.71  ? 308 ARG B NH2 1 
ATOM   5010  N N   . ARG B 1 290 ? 23.837  33.747  117.895 1.00 39.06  ? 309 ARG B N   1 
ATOM   5011  C CA  . ARG B 1 290 ? 24.265  34.872  117.074 1.00 39.98  ? 309 ARG B CA  1 
ATOM   5012  C C   . ARG B 1 290 ? 24.987  34.370  115.836 1.00 40.30  ? 309 ARG B C   1 
ATOM   5013  O O   . ARG B 1 290 ? 24.794  34.897  114.735 1.00 40.58  ? 309 ARG B O   1 
ATOM   5014  C CB  . ARG B 1 290 ? 25.138  35.800  117.927 1.00 41.56  ? 309 ARG B CB  1 
ATOM   5015  C CG  . ARG B 1 290 ? 25.809  37.007  117.256 1.00 43.97  ? 309 ARG B CG  1 
ATOM   5016  C CD  . ARG B 1 290 ? 25.049  37.628  116.106 1.00 44.99  ? 309 ARG B CD  1 
ATOM   5017  N NE  . ARG B 1 290 ? 23.797  38.252  116.490 1.00 45.43  ? 309 ARG B NE  1 
ATOM   5018  C CZ  . ARG B 1 290 ? 23.076  39.015  115.680 1.00 45.97  ? 309 ARG B CZ  1 
ATOM   5019  N NH1 . ARG B 1 290 ? 23.440  39.223  114.424 1.00 47.00  ? 309 ARG B NH1 1 
ATOM   5020  N NH2 . ARG B 1 290 ? 21.972  39.594  116.145 1.00 45.16  ? 309 ARG B NH2 1 
ATOM   5021  N N   . VAL B 1 291 ? 25.804  33.327  115.989 1.00 40.28  ? 310 VAL B N   1 
ATOM   5022  C CA  . VAL B 1 291 ? 26.442  32.747  114.812 1.00 40.08  ? 310 VAL B CA  1 
ATOM   5023  C C   . VAL B 1 291 ? 25.389  32.147  113.883 1.00 38.33  ? 310 VAL B C   1 
ATOM   5024  O O   . VAL B 1 291 ? 25.498  32.221  112.653 1.00 37.80  ? 310 VAL B O   1 
ATOM   5025  C CB  . VAL B 1 291 ? 27.489  31.693  115.218 1.00 39.86  ? 310 VAL B CB  1 
ATOM   5026  C CG1 . VAL B 1 291 ? 27.948  30.891  113.962 1.00 39.02  ? 310 VAL B CG1 1 
ATOM   5027  C CG2 . VAL B 1 291 ? 28.629  32.365  115.916 1.00 40.98  ? 310 VAL B CG2 1 
ATOM   5028  N N   . ALA B 1 292 ? 24.375  31.521  114.458 1.00 39.50  ? 311 ALA B N   1 
ATOM   5029  C CA  . ALA B 1 292 ? 23.312  30.973  113.633 1.00 37.45  ? 311 ALA B CA  1 
ATOM   5030  C C   . ALA B 1 292 ? 22.535  32.086  112.915 1.00 37.66  ? 311 ALA B C   1 
ATOM   5031  O O   . ALA B 1 292 ? 22.242  31.962  111.719 1.00 36.91  ? 311 ALA B O   1 
ATOM   5032  C CB  . ALA B 1 292 ? 22.430  30.078  114.511 1.00 36.69  ? 311 ALA B CB  1 
ATOM   5033  N N   . LYS B 1 293 ? 22.237  33.197  113.601 1.00 36.53  ? 312 LYS B N   1 
ATOM   5034  C CA  . LYS B 1 293 ? 21.582  34.314  112.919 1.00 36.86  ? 312 LYS B CA  1 
ATOM   5035  C C   . LYS B 1 293 ? 22.449  34.799  111.758 1.00 37.76  ? 312 LYS B C   1 
ATOM   5036  O O   . LYS B 1 293 ? 21.959  35.014  110.644 1.00 37.73  ? 312 LYS B O   1 
ATOM   5037  C CB  . LYS B 1 293 ? 21.262  35.443  113.897 1.00 37.96  ? 312 LYS B CB  1 
ATOM   5038  N N   . ASP B 1 294 ? 23.749  34.874  111.967 1.00 37.83  ? 313 ASP B N   1 
ATOM   5039  C CA  . ASP B 1 294 ? 24.633  35.427  110.963 1.00 39.86  ? 313 ASP B CA  1 
ATOM   5040  C C   . ASP B 1 294 ? 24.943  34.466  109.829 1.00 39.26  ? 313 ASP B C   1 
ATOM   5041  O O   . ASP B 1 294 ? 25.435  34.916  108.790 1.00 40.98  ? 313 ASP B O   1 
ATOM   5042  C CB  . ASP B 1 294 ? 25.944  35.842  111.625 1.00 42.22  ? 313 ASP B CB  1 
ATOM   5043  C CG  . ASP B 1 294 ? 25.819  37.119  112.473 1.00 44.38  ? 313 ASP B CG  1 
ATOM   5044  O OD1 . ASP B 1 294 ? 24.769  37.837  112.446 1.00 44.37  ? 313 ASP B OD1 1 
ATOM   5045  O OD2 . ASP B 1 294 ? 26.832  37.445  113.148 1.00 45.74  ? 313 ASP B OD2 1 
ATOM   5046  N N   . SER B 1 295 ? 24.690  33.162  110.005 1.00 39.90  ? 314 SER B N   1 
ATOM   5047  C CA  . SER B 1 295 ? 25.098  32.127  109.062 1.00 38.96  ? 314 SER B CA  1 
ATOM   5048  C C   . SER B 1 295 ? 23.952  31.623  108.166 1.00 37.13  ? 314 SER B C   1 
ATOM   5049  O O   . SER B 1 295 ? 24.181  30.789  107.280 1.00 37.05  ? 314 SER B O   1 
ATOM   5050  C CB  . SER B 1 295 ? 25.702  30.928  109.835 1.00 38.04  ? 314 SER B CB  1 
ATOM   5051  O OG  . SER B 1 295 ? 26.923  31.258  110.497 1.00 39.73  ? 314 SER B OG  1 
ATOM   5052  N N   . LEU B 1 296 ? 22.735  32.097  108.381 1.00 38.08  ? 315 LEU B N   1 
ATOM   5053  C CA  . LEU B 1 296 ? 21.599  31.544  107.672 1.00 36.57  ? 315 LEU B CA  1 
ATOM   5054  C C   . LEU B 1 296 ? 21.516  32.012  106.230 1.00 37.66  ? 315 LEU B C   1 
ATOM   5055  O O   . LEU B 1 296 ? 21.120  31.229  105.363 1.00 36.75  ? 315 LEU B O   1 
ATOM   5056  C CB  . LEU B 1 296 ? 20.326  31.906  108.430 1.00 36.15  ? 315 LEU B CB  1 
ATOM   5057  C CG  . LEU B 1 296 ? 18.987  31.627  107.769 1.00 34.82  ? 315 LEU B CG  1 
ATOM   5058  C CD1 . LEU B 1 296 ? 18.809  30.154  107.538 1.00 33.23  ? 315 LEU B CD1 1 
ATOM   5059  C CD2 . LEU B 1 296 ? 17.848  32.174  108.606 1.00 34.98  ? 315 LEU B CD2 1 
ATOM   5060  N N   . LYS B 1 297 ? 21.917  33.243  105.939 1.00 36.61  ? 316 LYS B N   1 
ATOM   5061  C CA  . LYS B 1 297 ? 21.616  33.807  104.626 1.00 37.52  ? 316 LYS B CA  1 
ATOM   5062  C C   . LYS B 1 297 ? 22.233  32.977  103.506 1.00 38.24  ? 316 LYS B C   1 
ATOM   5063  O O   . LYS B 1 297 ? 21.604  32.791  102.457 1.00 38.10  ? 316 LYS B O   1 
ATOM   5064  C CB  . LYS B 1 297 ? 22.071  35.275  104.567 1.00 40.47  ? 316 LYS B CB  1 
ATOM   5065  C CG  . LYS B 1 297 ? 21.872  35.952  103.216 1.00 42.57  ? 316 LYS B CG  1 
ATOM   5066  C CD  . LYS B 1 297 ? 21.724  37.505  103.318 1.00 44.55  ? 316 LYS B CD  1 
ATOM   5067  C CE  . LYS B 1 297 ? 20.309  37.977  102.791 1.00 46.65  ? 316 LYS B CE  1 
ATOM   5068  N NZ  . LYS B 1 297 ? 19.981  39.469  102.730 1.00 47.10  ? 316 LYS B NZ  1 
ATOM   5069  N N   . PHE B 1 298 ? 23.476  32.475  103.719 1.00 39.28  ? 317 PHE B N   1 
ATOM   5070  C CA  . PHE B 1 298 ? 24.175  31.791  102.611 1.00 40.20  ? 317 PHE B CA  1 
ATOM   5071  C C   . PHE B 1 298 ? 23.502  30.474  102.288 1.00 37.94  ? 317 PHE B C   1 
ATOM   5072  O O   . PHE B 1 298 ? 23.098  30.264  101.120 1.00 38.82  ? 317 PHE B O   1 
ATOM   5073  C CB  . PHE B 1 298 ? 25.650  31.613  102.951 1.00 40.75  ? 317 PHE B CB  1 
ATOM   5074  C CG  . PHE B 1 298 ? 26.381  30.874  101.871 1.00 41.37  ? 317 PHE B CG  1 
ATOM   5075  C CD1 . PHE B 1 298 ? 26.717  31.507  100.696 1.00 43.23  ? 317 PHE B CD1 1 
ATOM   5076  C CD2 . PHE B 1 298 ? 26.662  29.513  101.992 1.00 39.99  ? 317 PHE B CD2 1 
ATOM   5077  C CE1 . PHE B 1 298 ? 27.351  30.818  99.654  1.00 43.64  ? 317 PHE B CE1 1 
ATOM   5078  C CE2 . PHE B 1 298 ? 27.328  28.797  100.959 1.00 40.55  ? 317 PHE B CE2 1 
ATOM   5079  C CZ  . PHE B 1 298 ? 27.650  29.455  99.777  1.00 42.19  ? 317 PHE B CZ  1 
ATOM   5080  N N   . PRO B 1 299 ? 23.335  29.535  103.221 1.00 39.12  ? 318 PRO B N   1 
ATOM   5081  C CA  . PRO B 1 299 ? 22.705  28.253  102.877 1.00 37.44  ? 318 PRO B CA  1 
ATOM   5082  C C   . PRO B 1 299 ? 21.244  28.387  102.505 1.00 36.54  ? 318 PRO B C   1 
ATOM   5083  O O   . PRO B 1 299 ? 20.738  27.578  101.718 1.00 35.81  ? 318 PRO B O   1 
ATOM   5084  C CB  . PRO B 1 299 ? 22.873  27.408  104.153 1.00 35.78  ? 318 PRO B CB  1 
ATOM   5085  C CG  . PRO B 1 299 ? 23.028  28.444  105.277 1.00 36.33  ? 318 PRO B CG  1 
ATOM   5086  C CD  . PRO B 1 299 ? 23.775  29.589  104.633 1.00 38.49  ? 318 PRO B CD  1 
ATOM   5087  N N   . LEU B 1 300 ? 20.538  29.365  103.063 1.00 36.84  ? 319 LEU B N   1 
ATOM   5088  C CA  . LEU B 1 300 ? 19.148  29.563  102.658 1.00 36.08  ? 319 LEU B CA  1 
ATOM   5089  C C   . LEU B 1 300 ? 19.062  30.018  101.205 1.00 37.61  ? 319 LEU B C   1 
ATOM   5090  O O   . LEU B 1 300 ? 18.178  29.595  100.457 1.00 37.49  ? 319 LEU B O   1 
ATOM   5091  C CB  . LEU B 1 300 ? 18.472  30.581  103.570 1.00 35.86  ? 319 LEU B CB  1 
ATOM   5092  C CG  . LEU B 1 300 ? 17.041  30.929  103.187 1.00 35.42  ? 319 LEU B CG  1 
ATOM   5093  C CD1 . LEU B 1 300 ? 16.183  29.655  103.136 1.00 33.71  ? 319 LEU B CD1 1 
ATOM   5094  C CD2 . LEU B 1 300 ? 16.524  31.924  104.178 1.00 35.79  ? 319 LEU B CD2 1 
ATOM   5095  N N   . ALA B 1 301 ? 19.966  30.889  100.794 1.00 36.61  ? 320 ALA B N   1 
ATOM   5096  C CA  . ALA B 1 301 ? 19.915  31.362  99.417  1.00 38.43  ? 320 ALA B CA  1 
ATOM   5097  C C   . ALA B 1 301 ? 20.279  30.238  98.466  1.00 38.75  ? 320 ALA B C   1 
ATOM   5098  O O   . ALA B 1 301 ? 19.712  30.127  97.377  1.00 39.25  ? 320 ALA B O   1 
ATOM   5099  C CB  . ALA B 1 301 ? 20.842  32.572  99.223  1.00 40.95  ? 320 ALA B CB  1 
ATOM   5100  N N   . CYS B 1 302 ? 21.232  29.405  98.872  1.00 38.11  ? 321 CYS B N   1 
ATOM   5101  C CA  . CYS B 1 302 ? 21.593  28.235  98.080  1.00 38.38  ? 321 CYS B CA  1 
ATOM   5102  C C   . CYS B 1 302 ? 20.389  27.323  97.911  1.00 36.33  ? 321 CYS B C   1 
ATOM   5103  O O   . CYS B 1 302 ? 20.046  26.914  96.800  1.00 36.72  ? 321 CYS B O   1 
ATOM   5104  C CB  . CYS B 1 302 ? 22.741  27.502  98.757  1.00 38.21  ? 321 CYS B CB  1 
ATOM   5105  S SG  . CYS B 1 302 ? 24.336  28.285  98.467  1.00 40.14  ? 321 CYS B SG  1 
ATOM   5106  N N   . PHE B 1 303 ? 19.699  27.049  99.011  1.00 38.60  ? 322 PHE B N   1 
ATOM   5107  C CA  . PHE B 1 303 ? 18.474  26.271  98.955  1.00 36.64  ? 322 PHE B CA  1 
ATOM   5108  C C   . PHE B 1 303 ? 17.477  26.897  97.999  1.00 37.21  ? 322 PHE B C   1 
ATOM   5109  O O   . PHE B 1 303 ? 17.025  26.246  97.047  1.00 37.30  ? 322 PHE B O   1 
ATOM   5110  C CB  . PHE B 1 303 ? 17.888  26.159  100.348 1.00 34.37  ? 322 PHE B CB  1 
ATOM   5111  C CG  . PHE B 1 303 ? 16.575  25.505  100.384 1.00 32.46  ? 322 PHE B CG  1 
ATOM   5112  C CD1 . PHE B 1 303 ? 16.459  24.124  100.153 1.00 31.76  ? 322 PHE B CD1 1 
ATOM   5113  C CD2 . PHE B 1 303 ? 15.436  26.254  100.646 1.00 32.52  ? 322 PHE B CD2 1 
ATOM   5114  C CE1 . PHE B 1 303 ? 15.226  23.513  100.203 1.00 30.86  ? 322 PHE B CE1 1 
ATOM   5115  C CE2 . PHE B 1 303 ? 14.202  25.655  100.701 1.00 31.38  ? 322 PHE B CE2 1 
ATOM   5116  C CZ  . PHE B 1 303 ? 14.086  24.271  100.481 1.00 30.76  ? 322 PHE B CZ  1 
ATOM   5117  N N   . LEU B 1 304 ? 17.123  28.165  98.233  1.00 36.44  ? 323 LEU B N   1 
ATOM   5118  C CA  . LEU B 1 304 ? 16.079  28.791  97.417  1.00 36.76  ? 323 LEU B CA  1 
ATOM   5119  C C   . LEU B 1 304 ? 16.498  28.903  95.944  1.00 38.77  ? 323 LEU B C   1 
ATOM   5120  O O   . LEU B 1 304 ? 15.645  28.890  95.055  1.00 39.12  ? 323 LEU B O   1 
ATOM   5121  C CB  . LEU B 1 304 ? 15.729  30.170  97.982  1.00 37.23  ? 323 LEU B CB  1 
ATOM   5122  C CG  . LEU B 1 304 ? 15.063  30.219  99.347  1.00 35.75  ? 323 LEU B CG  1 
ATOM   5123  C CD1 . LEU B 1 304 ? 14.834  31.652  99.805  1.00 36.64  ? 323 LEU B CD1 1 
ATOM   5124  C CD2 . LEU B 1 304 ? 13.764  29.506  99.326  1.00 34.73  ? 323 LEU B CD2 1 
ATOM   5125  N N   . ALA B 1 305 ? 17.800  29.040  95.666  1.00 38.36  ? 324 ALA B N   1 
ATOM   5126  C CA  . ALA B 1 305 ? 18.243  29.113  94.283  1.00 40.05  ? 324 ALA B CA  1 
ATOM   5127  C C   . ALA B 1 305 ? 17.776  27.885  93.520  1.00 39.23  ? 324 ALA B C   1 
ATOM   5128  O O   . ALA B 1 305 ? 17.265  28.002  92.399  1.00 40.17  ? 324 ALA B O   1 
ATOM   5129  C CB  . ALA B 1 305 ? 19.762  29.246  94.226  1.00 41.77  ? 324 ALA B CB  1 
ATOM   5130  N N   . GLY B 1 306 ? 17.902  26.701  94.135  1.00 40.41  ? 325 GLY B N   1 
ATOM   5131  C CA  . GLY B 1 306 ? 17.629  25.455  93.455  1.00 39.85  ? 325 GLY B CA  1 
ATOM   5132  C C   . GLY B 1 306 ? 16.318  24.785  93.825  1.00 38.37  ? 325 GLY B C   1 
ATOM   5133  O O   . GLY B 1 306 ? 15.923  23.803  93.191  1.00 37.97  ? 325 GLY B O   1 
ATOM   5134  N N   . ALA B 1 307 ? 15.613  25.297  94.823  1.00 38.26  ? 326 ALA B N   1 
ATOM   5135  C CA  . ALA B 1 307 ? 14.497  24.526  95.343  1.00 36.87  ? 326 ALA B CA  1 
ATOM   5136  C C   . ALA B 1 307 ? 13.379  24.381  94.316  1.00 37.34  ? 326 ALA B C   1 
ATOM   5137  O O   . ALA B 1 307 ? 13.128  25.265  93.487  1.00 38.66  ? 326 ALA B O   1 
ATOM   5138  C CB  . ALA B 1 307 ? 13.937  25.159  96.605  1.00 35.93  ? 326 ALA B CB  1 
ATOM   5139  N N   . GLN B 1 308 ? 12.693  23.248  94.392  1.00 36.53  ? 327 GLN B N   1 
ATOM   5140  C CA  . GLN B 1 308 ? 11.511  22.967  93.601  1.00 36.92  ? 327 GLN B CA  1 
ATOM   5141  C C   . GLN B 1 308 ? 10.425  22.483  94.547  1.00 35.96  ? 327 GLN B C   1 
ATOM   5142  O O   . GLN B 1 308 ? 10.562  22.539  95.761  1.00 34.78  ? 327 GLN B O   1 
ATOM   5143  C CB  . GLN B 1 308 ? 11.793  21.939  92.505  1.00 37.87  ? 327 GLN B CB  1 
ATOM   5144  C CG  . GLN B 1 308 ? 13.099  22.172  91.773  1.00 38.85  ? 327 GLN B CG  1 
ATOM   5145  C CD  . GLN B 1 308 ? 13.063  23.357  90.803  1.00 40.31  ? 327 GLN B CD  1 
ATOM   5146  O OE1 . GLN B 1 308 ? 12.041  23.640  90.157  1.00 41.74  ? 327 GLN B OE1 1 
ATOM   5147  N NE2 . GLN B 1 308 ? 14.202  24.032  90.674  1.00 41.15  ? 327 GLN B NE2 1 
ATOM   5148  N N   . GLU B 1 309 ? 9.305   22.093  93.983  1.00 38.04  ? 328 GLU B N   1 
ATOM   5149  C CA  . GLU B 1 309 ? 8.247   21.481  94.764  1.00 37.71  ? 328 GLU B CA  1 
ATOM   5150  C C   . GLU B 1 309 ? 8.820   20.274  95.485  1.00 36.24  ? 328 GLU B C   1 
ATOM   5151  O O   . GLU B 1 309 ? 9.721   19.609  94.983  1.00 36.47  ? 328 GLU B O   1 
ATOM   5152  C CB  . GLU B 1 309 ? 7.101   21.105  93.823  1.00 40.08  ? 328 GLU B CB  1 
ATOM   5153  C CG  . GLU B 1 309 ? 5.845   20.641  94.474  1.00 42.14  ? 328 GLU B CG  1 
ATOM   5154  C CD  . GLU B 1 309 ? 4.635   20.616  93.548  1.00 45.08  ? 328 GLU B CD  1 
ATOM   5155  O OE1 . GLU B 1 309 ? 4.610   21.240  92.423  1.00 46.73  ? 328 GLU B OE1 1 
ATOM   5156  O OE2 . GLU B 1 309 ? 3.677   19.933  93.978  1.00 45.71  ? 328 GLU B OE2 1 
ATOM   5157  N N   . ASN B 1 310 ? 8.347   20.029  96.703  1.00 35.22  ? 329 ASN B N   1 
ATOM   5158  C CA  . ASN B 1 310 ? 8.799   18.920  97.546  1.00 33.87  ? 329 ASN B CA  1 
ATOM   5159  C C   . ASN B 1 310 ? 10.255  19.027  97.993  1.00 32.99  ? 329 ASN B C   1 
ATOM   5160  O O   . ASN B 1 310 ? 10.854  18.023  98.409  1.00 31.47  ? 329 ASN B O   1 
ATOM   5161  C CB  . ASN B 1 310 ? 8.624   17.569  96.851  1.00 33.32  ? 329 ASN B CB  1 
ATOM   5162  C CG  . ASN B 1 310 ? 7.227   17.344  96.412  1.00 34.49  ? 329 ASN B CG  1 
ATOM   5163  O OD1 . ASN B 1 310 ? 6.286   17.519  97.192  1.00 34.72  ? 329 ASN B OD1 1 
ATOM   5164  N ND2 . ASN B 1 310 ? 7.066   16.985  95.151  1.00 35.80  ? 329 ASN B ND2 1 
ATOM   5165  N N   . CYS B 1 311 ? 10.842  20.215  97.933  1.00 32.78  ? 330 CYS B N   1 
ATOM   5166  C CA  . CYS B 1 311 ? 12.134  20.424  98.563  1.00 32.11  ? 330 CYS B CA  1 
ATOM   5167  C C   . CYS B 1 311 ? 11.959  21.066  99.933  1.00 31.02  ? 330 CYS B C   1 
ATOM   5168  O O   . CYS B 1 311 ? 11.024  21.832  100.168 1.00 31.49  ? 330 CYS B O   1 
ATOM   5169  C CB  . CYS B 1 311 ? 13.039  21.259  97.676  1.00 33.69  ? 330 CYS B CB  1 
ATOM   5170  S SG  . CYS B 1 311 ? 13.392  20.444  96.157  1.00 34.90  ? 330 CYS B SG  1 
ATOM   5171  N N   . TYR B 1 312 ? 12.854  20.693  100.856 1.00 32.40  ? 331 TYR B N   1 
ATOM   5172  C CA  . TYR B 1 312 ? 12.738  21.100  102.246 1.00 31.43  ? 331 TYR B CA  1 
ATOM   5173  C C   . TYR B 1 312 ? 14.071  21.526  102.826 1.00 31.41  ? 331 TYR B C   1 
ATOM   5174  O O   . TYR B 1 312 ? 15.111  20.939  102.523 1.00 31.78  ? 331 TYR B O   1 
ATOM   5175  C CB  . TYR B 1 312 ? 12.200  19.962  103.096 1.00 30.31  ? 331 TYR B CB  1 
ATOM   5176  C CG  . TYR B 1 312 ? 10.775  19.667  102.824 1.00 30.43  ? 331 TYR B CG  1 
ATOM   5177  C CD1 . TYR B 1 312 ? 10.395  18.779  101.801 1.00 30.63  ? 331 TYR B CD1 1 
ATOM   5178  C CD2 . TYR B 1 312 ? 9.792   20.284  103.573 1.00 30.99  ? 331 TYR B CD2 1 
ATOM   5179  C CE1 . TYR B 1 312 ? 9.084   18.528  101.552 1.00 30.98  ? 331 TYR B CE1 1 
ATOM   5180  C CE2 . TYR B 1 312 ? 8.488   20.020  103.338 1.00 31.54  ? 331 TYR B CE2 1 
ATOM   5181  C CZ  . TYR B 1 312 ? 8.133   19.152  102.330 1.00 31.76  ? 331 TYR B CZ  1 
ATOM   5182  O OH  . TYR B 1 312 ? 6.780   18.957  102.128 1.00 32.84  ? 331 TYR B OH  1 
ATOM   5183  N N   . PHE B 1 313 ? 14.015  22.539  103.683 1.00 28.96  ? 332 PHE B N   1 
ATOM   5184  C CA  . PHE B 1 313 ? 15.173  23.092  104.380 1.00 29.27  ? 332 PHE B CA  1 
ATOM   5185  C C   . PHE B 1 313 ? 15.161  22.722  105.861 1.00 28.59  ? 332 PHE B C   1 
ATOM   5186  O O   . PHE B 1 313 ? 14.107  22.692  106.502 1.00 28.29  ? 332 PHE B O   1 
ATOM   5187  C CB  . PHE B 1 313 ? 15.184  24.620  104.241 1.00 30.60  ? 332 PHE B CB  1 
ATOM   5188  C CG  . PHE B 1 313 ? 16.487  25.284  104.597 1.00 31.27  ? 332 PHE B CG  1 
ATOM   5189  C CD1 . PHE B 1 313 ? 17.642  24.953  103.944 1.00 32.05  ? 332 PHE B CD1 1 
ATOM   5190  C CD2 . PHE B 1 313 ? 16.523  26.299  105.554 1.00 31.77  ? 332 PHE B CD2 1 
ATOM   5191  C CE1 . PHE B 1 313 ? 18.804  25.580  104.236 1.00 33.47  ? 332 PHE B CE1 1 
ATOM   5192  C CE2 . PHE B 1 313 ? 17.692  26.970  105.839 1.00 33.03  ? 332 PHE B CE2 1 
ATOM   5193  C CZ  . PHE B 1 313 ? 18.834  26.610  105.176 1.00 34.00  ? 332 PHE B CZ  1 
ATOM   5194  N N   . ILE B 1 314 ? 16.357  22.462  106.383 1.00 30.29  ? 333 ILE B N   1 
ATOM   5195  C CA  . ILE B 1 314 ? 16.635  22.193  107.794 1.00 30.31  ? 333 ILE B CA  1 
ATOM   5196  C C   . ILE B 1 314 ? 17.856  23.041  108.150 1.00 31.27  ? 333 ILE B C   1 
ATOM   5197  O O   . ILE B 1 314 ? 18.820  23.125  107.381 1.00 32.32  ? 333 ILE B O   1 
ATOM   5198  C CB  . ILE B 1 314 ? 16.904  20.700  108.072 1.00 29.73  ? 333 ILE B CB  1 
ATOM   5199  C CG1 . ILE B 1 314 ? 15.735  19.860  107.582 1.00 29.18  ? 333 ILE B CG1 1 
ATOM   5200  C CG2 . ILE B 1 314 ? 17.105  20.415  109.562 1.00 30.60  ? 333 ILE B CG2 1 
ATOM   5201  C CD1 . ILE B 1 314 ? 15.822  18.326  107.927 1.00 28.85  ? 333 ILE B CD1 1 
ATOM   5202  N N   . TYR B 1 315 ? 17.801  23.708  109.295 1.00 28.91  ? 334 TYR B N   1 
ATOM   5203  C CA  . TYR B 1 315 ? 18.818  24.692  109.653 1.00 30.21  ? 334 TYR B CA  1 
ATOM   5204  C C   . TYR B 1 315 ? 19.074  24.623  111.151 1.00 30.96  ? 334 TYR B C   1 
ATOM   5205  O O   . TYR B 1 315 ? 18.220  24.982  111.959 1.00 31.65  ? 334 TYR B O   1 
ATOM   5206  C CB  . TYR B 1 315 ? 18.395  26.109  109.228 1.00 31.03  ? 334 TYR B CB  1 
ATOM   5207  C CG  . TYR B 1 315 ? 19.511  27.080  109.422 1.00 32.58  ? 334 TYR B CG  1 
ATOM   5208  C CD1 . TYR B 1 315 ? 20.611  27.054  108.593 1.00 33.21  ? 334 TYR B CD1 1 
ATOM   5209  C CD2 . TYR B 1 315 ? 19.492  27.978  110.474 1.00 33.74  ? 334 TYR B CD2 1 
ATOM   5210  C CE1 . TYR B 1 315 ? 21.659  27.911  108.790 1.00 35.07  ? 334 TYR B CE1 1 
ATOM   5211  C CE2 . TYR B 1 315 ? 20.531  28.859  110.683 1.00 35.45  ? 334 TYR B CE2 1 
ATOM   5212  C CZ  . TYR B 1 315 ? 21.624  28.813  109.838 1.00 36.19  ? 334 TYR B CZ  1 
ATOM   5213  O OH  . TYR B 1 315 ? 22.688  29.673  110.020 1.00 38.36  ? 334 TYR B OH  1 
ATOM   5214  N N   . ASN B 1 316 ? 20.245  24.153  111.510 1.00 32.43  ? 335 ASN B N   1 
ATOM   5215  C CA  . ASN B 1 316 ? 20.655  23.999  112.901 1.00 33.58  ? 335 ASN B CA  1 
ATOM   5216  C C   . ASN B 1 316 ? 22.122  23.598  112.910 1.00 34.50  ? 335 ASN B C   1 
ATOM   5217  O O   . ASN B 1 316 ? 22.788  23.579  111.863 1.00 34.13  ? 335 ASN B O   1 
ATOM   5218  C CB  . ASN B 1 316 ? 19.786  22.975  113.609 1.00 33.26  ? 335 ASN B CB  1 
ATOM   5219  C CG  . ASN B 1 316 ? 19.765  21.677  112.880 1.00 32.10  ? 335 ASN B CG  1 
ATOM   5220  O OD1 . ASN B 1 316 ? 20.799  21.134  112.505 1.00 32.17  ? 335 ASN B OD1 1 
ATOM   5221  N ND2 . ASN B 1 316 ? 18.575  21.185  112.628 1.00 30.89  ? 335 ASN B ND2 1 
ATOM   5222  N N   . TRP B 1 317 ? 22.645  23.290  114.081 1.00 34.77  ? 336 TRP B N   1 
ATOM   5223  C CA  . TRP B 1 317 ? 24.028  22.838  114.189 1.00 35.51  ? 336 TRP B CA  1 
ATOM   5224  C C   . TRP B 1 317 ? 24.113  21.392  114.685 1.00 35.52  ? 336 TRP B C   1 
ATOM   5225  O O   . TRP B 1 317 ? 25.212  20.951  115.047 1.00 36.24  ? 336 TRP B O   1 
ATOM   5226  C CB  . TRP B 1 317 ? 24.866  23.804  115.057 1.00 35.90  ? 336 TRP B CB  1 
ATOM   5227  C CG  . TRP B 1 317 ? 24.399  24.048  116.473 1.00 35.25  ? 336 TRP B CG  1 
ATOM   5228  C CD1 . TRP B 1 317 ? 24.716  23.310  117.568 1.00 35.43  ? 336 TRP B CD1 1 
ATOM   5229  C CD2 . TRP B 1 317 ? 23.557  25.110  116.937 1.00 34.96  ? 336 TRP B CD2 1 
ATOM   5230  N NE1 . TRP B 1 317 ? 24.123  23.840  118.679 1.00 35.15  ? 336 TRP B NE1 1 
ATOM   5231  C CE2 . TRP B 1 317 ? 23.403  24.941  118.325 1.00 34.67  ? 336 TRP B CE2 1 
ATOM   5232  C CE3 . TRP B 1 317 ? 22.908  26.181  116.310 1.00 35.32  ? 336 TRP B CE3 1 
ATOM   5233  C CZ2 . TRP B 1 317 ? 22.631  25.788  119.099 1.00 34.87  ? 336 TRP B CZ2 1 
ATOM   5234  C CZ3 . TRP B 1 317 ? 22.120  27.043  117.086 1.00 35.25  ? 336 TRP B CZ3 1 
ATOM   5235  C CH2 . TRP B 1 317 ? 21.992  26.843  118.455 1.00 35.02  ? 336 TRP B CH2 1 
ATOM   5236  N N   . GLY B 1 318 ? 23.017  20.627  114.644 1.00 33.54  ? 337 GLY B N   1 
ATOM   5237  C CA  . GLY B 1 318 ? 23.098  19.219  115.004 1.00 33.89  ? 337 GLY B CA  1 
ATOM   5238  C C   . GLY B 1 318 ? 21.765  18.488  115.034 1.00 34.06  ? 337 GLY B C   1 
ATOM   5239  O O   . GLY B 1 318 ? 20.722  18.972  114.551 1.00 33.62  ? 337 GLY B O   1 
ATOM   5240  N N   . TYR B 1 319 ? 21.822  17.290  115.637 1.00 32.26  ? 338 TYR B N   1 
ATOM   5241  C CA  . TYR B 1 319 ? 20.715  16.334  115.583 1.00 32.71  ? 338 TYR B CA  1 
ATOM   5242  C C   . TYR B 1 319 ? 20.050  16.047  116.919 1.00 33.19  ? 338 TYR B C   1 
ATOM   5243  O O   . TYR B 1 319 ? 19.007  15.378  116.929 1.00 34.06  ? 338 TYR B O   1 
ATOM   5244  C CB  . TYR B 1 319 ? 21.185  15.005  114.998 1.00 33.92  ? 338 TYR B CB  1 
ATOM   5245  C CG  . TYR B 1 319 ? 21.619  15.148  113.591 1.00 34.17  ? 338 TYR B CG  1 
ATOM   5246  C CD1 . TYR B 1 319 ? 20.707  15.490  112.631 1.00 34.21  ? 338 TYR B CD1 1 
ATOM   5247  C CD2 . TYR B 1 319 ? 22.948  14.947  113.228 1.00 35.06  ? 338 TYR B CD2 1 
ATOM   5248  C CE1 . TYR B 1 319 ? 21.083  15.642  111.346 1.00 34.68  ? 338 TYR B CE1 1 
ATOM   5249  C CE2 . TYR B 1 319 ? 23.349  15.099  111.945 1.00 35.40  ? 338 TYR B CE2 1 
ATOM   5250  C CZ  . TYR B 1 319 ? 22.397  15.451  110.992 1.00 35.25  ? 338 TYR B CZ  1 
ATOM   5251  O OH  . TYR B 1 319 ? 22.724  15.603  109.664 1.00 35.78  ? 338 TYR B OH  1 
ATOM   5252  N N   . ARG B 1 320 ? 20.634  16.488  118.039 1.00 37.09  ? 339 ARG B N   1 
ATOM   5253  C CA  . ARG B 1 320 ? 19.913  16.538  119.306 1.00 37.68  ? 339 ARG B CA  1 
ATOM   5254  C C   . ARG B 1 320 ? 19.073  17.809  119.315 1.00 36.33  ? 339 ARG B C   1 
ATOM   5255  O O   . ARG B 1 320 ? 19.441  18.817  118.715 1.00 35.55  ? 339 ARG B O   1 
ATOM   5256  C CB  . ARG B 1 320 ? 20.876  16.502  120.490 1.00 38.89  ? 339 ARG B CB  1 
ATOM   5257  C CG  . ARG B 1 320 ? 21.699  15.227  120.544 1.00 41.38  ? 339 ARG B CG  1 
ATOM   5258  C CD  . ARG B 1 320 ? 22.679  15.141  121.752 1.00 43.91  ? 339 ARG B CD  1 
ATOM   5259  N NE  . ARG B 1 320 ? 23.707  14.111  121.570 1.00 47.17  ? 339 ARG B NE  1 
ATOM   5260  C CZ  . ARG B 1 320 ? 23.526  12.796  121.723 1.00 50.44  ? 339 ARG B CZ  1 
ATOM   5261  N NH1 . ARG B 1 320 ? 22.364  12.294  122.119 1.00 51.74  ? 339 ARG B NH1 1 
ATOM   5262  N NH2 . ARG B 1 320 ? 24.545  11.962  121.487 1.00 51.94  ? 339 ARG B NH2 1 
ATOM   5263  N N   . MET B 1 321 ? 17.922  17.746  119.977 1.00 38.42  ? 340 MET B N   1 
ATOM   5264  C CA  . MET B 1 321 ? 17.030  18.900  120.009 1.00 37.67  ? 340 MET B CA  1 
ATOM   5265  C C   . MET B 1 321 ? 17.776  20.184  120.352 1.00 36.59  ? 340 MET B C   1 
ATOM   5266  O O   . MET B 1 321 ? 17.598  21.227  119.715 1.00 35.82  ? 340 MET B O   1 
ATOM   5267  C CB  . MET B 1 321 ? 15.932  18.677  121.046 1.00 38.64  ? 340 MET B CB  1 
ATOM   5268  C CG  . MET B 1 321 ? 14.674  19.435  120.739 1.00 38.19  ? 340 MET B CG  1 
ATOM   5269  S SD  . MET B 1 321 ? 13.481  19.455  122.119 1.00 40.03  ? 340 MET B SD  1 
ATOM   5270  C CE  . MET B 1 321 ? 14.458  20.050  123.503 1.00 40.21  ? 340 MET B CE  1 
ATOM   5271  N N   . GLU B 1 322 ? 18.577  20.147  121.399 1.00 34.07  ? 341 GLU B N   1 
ATOM   5272  C CA  . GLU B 1 322 ? 19.207  21.378  121.823 1.00 33.81  ? 341 GLU B CA  1 
ATOM   5273  C C   . GLU B 1 322 ? 20.174  21.945  120.790 1.00 33.20  ? 341 GLU B C   1 
ATOM   5274  O O   . GLU B 1 322 ? 20.613  23.076  120.970 1.00 33.21  ? 341 GLU B O   1 
ATOM   5275  C CB  . GLU B 1 322 ? 19.914  21.148  123.168 1.00 52.52  ? 341 GLU B CB  1 
ATOM   5276  C CG  . GLU B 1 322 ? 21.061  20.155  123.131 1.00 52.83  ? 341 GLU B CG  1 
ATOM   5277  C CD  . GLU B 1 322 ? 20.659  18.697  123.512 1.00 53.64  ? 341 GLU B CD  1 
ATOM   5278  O OE1 . GLU B 1 322 ? 19.457  18.314  123.310 1.00 53.74  ? 341 GLU B OE1 1 
ATOM   5279  O OE2 . GLU B 1 322 ? 21.568  17.952  124.018 1.00 54.60  ? 341 GLU B OE2 1 
ATOM   5280  N N   . ASN B 1 323 ? 20.521  21.226  119.742 1.00 35.57  ? 342 ASN B N   1 
ATOM   5281  C CA  . ASN B 1 323 ? 21.479  21.769  118.774 1.00 35.52  ? 342 ASN B CA  1 
ATOM   5282  C C   . ASN B 1 323 ? 20.848  22.787  117.798 1.00 34.98  ? 342 ASN B C   1 
ATOM   5283  O O   . ASN B 1 323 ? 21.154  22.769  116.604 1.00 35.16  ? 342 ASN B O   1 
ATOM   5284  C CB  . ASN B 1 323 ? 22.133  20.620  118.001 1.00 36.35  ? 342 ASN B CB  1 
ATOM   5285  C CG  . ASN B 1 323 ? 22.818  19.584  118.905 1.00 36.81  ? 342 ASN B CG  1 
ATOM   5286  O OD1 . ASN B 1 323 ? 22.866  18.398  118.564 1.00 37.92  ? 342 ASN B OD1 1 
ATOM   5287  N ND2 . ASN B 1 323 ? 23.354  20.018  120.038 1.00 37.36  ? 342 ASN B ND2 1 
ATOM   5288  N N   . GLY B 1 324 ? 19.952  23.654  118.277 1.00 33.42  ? 343 GLY B N   1 
ATOM   5289  C CA  . GLY B 1 324 ? 19.400  24.716  117.459 1.00 33.48  ? 343 GLY B CA  1 
ATOM   5290  C C   . GLY B 1 324 ? 18.137  24.363  116.735 1.00 33.30  ? 343 GLY B C   1 
ATOM   5291  O O   . GLY B 1 324 ? 17.570  25.215  116.033 1.00 33.30  ? 343 GLY B O   1 
ATOM   5292  N N   . CYS B 1 325 ? 17.665  23.138  116.916 1.00 34.78  ? 344 CYS B N   1 
ATOM   5293  C CA  . CYS B 1 325 ? 16.600  22.567  116.113 1.00 34.63  ? 344 CYS B CA  1 
ATOM   5294  C C   . CYS B 1 325 ? 15.264  23.252  116.305 1.00 34.32  ? 344 CYS B C   1 
ATOM   5295  O O   . CYS B 1 325 ? 14.390  23.084  115.447 1.00 34.73  ? 344 CYS B O   1 
ATOM   5296  C CB  . CYS B 1 325 ? 16.468  21.079  116.472 1.00 35.45  ? 344 CYS B CB  1 
ATOM   5297  S SG  . CYS B 1 325 ? 17.972  20.199  116.094 1.00 36.53  ? 344 CYS B SG  1 
ATOM   5298  N N   . LEU B 1 326 ? 15.073  23.950  117.414 1.00 33.08  ? 345 LEU B N   1 
ATOM   5299  C CA  . LEU B 1 326 ? 13.863  24.699  117.695 1.00 33.03  ? 345 LEU B CA  1 
ATOM   5300  C C   . LEU B 1 326 ? 14.134  26.192  117.762 1.00 33.31  ? 345 LEU B C   1 
ATOM   5301  O O   . LEU B 1 326 ? 13.286  26.945  118.245 1.00 33.72  ? 345 LEU B O   1 
ATOM   5302  C CB  . LEU B 1 326 ? 13.224  24.238  119.003 1.00 33.84  ? 345 LEU B CB  1 
ATOM   5303  C CG  . LEU B 1 326 ? 12.929  22.732  119.063 1.00 34.87  ? 345 LEU B CG  1 
ATOM   5304  C CD1 . LEU B 1 326 ? 12.106  22.345  120.268 1.00 36.30  ? 345 LEU B CD1 1 
ATOM   5305  C CD2 . LEU B 1 326 ? 12.175  22.282  117.845 1.00 34.86  ? 345 LEU B CD2 1 
ATOM   5306  N N   . GLU B 1 327 ? 15.303  26.635  117.327 1.00 34.55  ? 346 GLU B N   1 
ATOM   5307  C CA  . GLU B 1 327 ? 15.467  28.046  117.066 1.00 35.00  ? 346 GLU B CA  1 
ATOM   5308  C C   . GLU B 1 327 ? 14.558  28.406  115.908 1.00 35.39  ? 346 GLU B C   1 
ATOM   5309  O O   . GLU B 1 327 ? 14.141  27.551  115.135 1.00 36.12  ? 346 GLU B O   1 
ATOM   5310  C CB  . GLU B 1 327 ? 16.917  28.408  116.738 1.00 35.69  ? 346 GLU B CB  1 
ATOM   5311  C CG  . GLU B 1 327 ? 17.929  28.093  117.861 1.00 36.04  ? 346 GLU B CG  1 
ATOM   5312  C CD  . GLU B 1 327 ? 17.707  28.890  119.146 1.00 36.96  ? 346 GLU B CD  1 
ATOM   5313  O OE1 . GLU B 1 327 ? 17.378  30.086  119.074 1.00 38.07  ? 346 GLU B OE1 1 
ATOM   5314  O OE2 . GLU B 1 327 ? 17.856  28.322  120.256 1.00 37.17  ? 346 GLU B OE2 1 
ATOM   5315  N N   . TRP B 1 328 ? 14.200  29.674  115.818 1.00 36.19  ? 347 TRP B N   1 
ATOM   5316  C CA  . TRP B 1 328 ? 13.421  30.153  114.694 1.00 36.46  ? 347 TRP B CA  1 
ATOM   5317  C C   . TRP B 1 328 ? 14.040  31.449  114.214 1.00 37.92  ? 347 TRP B C   1 
ATOM   5318  O O   . TRP B 1 328 ? 14.880  32.047  114.884 1.00 38.85  ? 347 TRP B O   1 
ATOM   5319  C CB  . TRP B 1 328 ? 11.950  30.342  115.047 1.00 36.37  ? 347 TRP B CB  1 
ATOM   5320  C CG  . TRP B 1 328 ? 11.021  30.255  113.809 1.00 36.48  ? 347 TRP B CG  1 
ATOM   5321  C CD1 . TRP B 1 328 ? 10.211  31.256  113.316 1.00 37.23  ? 347 TRP B CD1 1 
ATOM   5322  C CD2 . TRP B 1 328 ? 10.822  29.118  112.937 1.00 36.07  ? 347 TRP B CD2 1 
ATOM   5323  N NE1 . TRP B 1 328 ? 9.517   30.808  112.201 1.00 37.56  ? 347 TRP B NE1 1 
ATOM   5324  C CE2 . TRP B 1 328 ? 9.876   29.504  111.950 1.00 36.76  ? 347 TRP B CE2 1 
ATOM   5325  C CE3 . TRP B 1 328 ? 11.362  27.821  112.884 1.00 35.69  ? 347 TRP B CE3 1 
ATOM   5326  C CZ2 . TRP B 1 328 ? 9.462   28.638  110.940 1.00 36.87  ? 347 TRP B CZ2 1 
ATOM   5327  C CZ3 . TRP B 1 328 ? 10.939  26.961  111.878 1.00 35.96  ? 347 TRP B CZ3 1 
ATOM   5328  C CH2 . TRP B 1 328 ? 9.996   27.378  110.919 1.00 36.65  ? 347 TRP B CH2 1 
ATOM   5329  N N   . TYR B 1 329 ? 13.630  31.862  113.021 1.00 36.28  ? 348 TYR B N   1 
ATOM   5330  C CA  . TYR B 1 329 ? 14.216  32.991  112.320 1.00 37.87  ? 348 TYR B CA  1 
ATOM   5331  C C   . TYR B 1 329 ? 13.130  33.688  111.510 1.00 38.49  ? 348 TYR B C   1 
ATOM   5332  O O   . TYR B 1 329 ? 12.303  33.016  110.884 1.00 37.99  ? 348 TYR B O   1 
ATOM   5333  C CB  . TYR B 1 329 ? 15.359  32.528  111.405 1.00 38.33  ? 348 TYR B CB  1 
ATOM   5334  C CG  . TYR B 1 329 ? 16.360  31.721  112.124 1.00 37.87  ? 348 TYR B CG  1 
ATOM   5335  C CD1 . TYR B 1 329 ? 16.271  30.347  112.165 1.00 36.66  ? 348 TYR B CD1 1 
ATOM   5336  C CD2 . TYR B 1 329 ? 17.385  32.339  112.799 1.00 38.36  ? 348 TYR B CD2 1 
ATOM   5337  C CE1 . TYR B 1 329 ? 17.206  29.586  112.859 1.00 36.31  ? 348 TYR B CE1 1 
ATOM   5338  C CE2 . TYR B 1 329 ? 18.291  31.630  113.501 1.00 38.04  ? 348 TYR B CE2 1 
ATOM   5339  C CZ  . TYR B 1 329 ? 18.206  30.248  113.526 1.00 37.03  ? 348 TYR B CZ  1 
ATOM   5340  O OH  . TYR B 1 329 ? 19.158  29.615  114.249 1.00 37.01  ? 348 TYR B OH  1 
ATOM   5341  N N   . PRO B 1 330 ? 13.088  35.005  111.512 1.00 39.02  ? 349 PRO B N   1 
ATOM   5342  C CA  . PRO B 1 330 ? 12.003  35.671  110.796 1.00 39.68  ? 349 PRO B CA  1 
ATOM   5343  C C   . PRO B 1 330 ? 11.981  35.301  109.339 1.00 39.51  ? 349 PRO B C   1 
ATOM   5344  O O   . PRO B 1 330 ? 10.912  35.353  108.716 1.00 39.80  ? 349 PRO B O   1 
ATOM   5345  C CB  . PRO B 1 330 ? 12.295  37.162  111.016 1.00 41.31  ? 349 PRO B CB  1 
ATOM   5346  C CG  . PRO B 1 330 ? 13.680  37.245  111.464 1.00 41.64  ? 349 PRO B CG  1 
ATOM   5347  C CD  . PRO B 1 330 ? 14.010  35.960  112.153 1.00 40.07  ? 349 PRO B CD  1 
ATOM   5348  N N   . GLU B 1 331 ? 13.124  34.892  108.779 1.00 40.57  ? 350 GLU B N   1 
ATOM   5349  C CA  . GLU B 1 331 ? 13.159  34.475  107.377 1.00 40.46  ? 350 GLU B CA  1 
ATOM   5350  C C   . GLU B 1 331 ? 12.160  33.365  107.087 1.00 39.84  ? 350 GLU B C   1 
ATOM   5351  O O   . GLU B 1 331 ? 11.721  33.195  105.943 1.00 40.72  ? 350 GLU B O   1 
ATOM   5352  C CB  . GLU B 1 331 ? 14.572  33.992  107.004 1.00 40.81  ? 350 GLU B CB  1 
ATOM   5353  C CG  . GLU B 1 331 ? 15.613  35.116  106.779 1.00 41.75  ? 350 GLU B CG  1 
ATOM   5354  C CD  . GLU B 1 331 ? 16.282  35.648  108.051 1.00 42.38  ? 350 GLU B CD  1 
ATOM   5355  O OE1 . GLU B 1 331 ? 16.032  35.126  109.177 1.00 41.48  ? 350 GLU B OE1 1 
ATOM   5356  O OE2 . GLU B 1 331 ? 17.077  36.619  107.908 1.00 43.93  ? 350 GLU B OE2 1 
ATOM   5357  N N   . PHE B 1 332 ? 11.831  32.571  108.083 1.00 37.69  ? 351 PHE B N   1 
ATOM   5358  C CA  . PHE B 1 332 ? 10.967  31.416  107.887 1.00 36.67  ? 351 PHE B CA  1 
ATOM   5359  C C   . PHE B 1 332 ? 9.507   31.803  108.000 1.00 36.34  ? 351 PHE B C   1 
ATOM   5360  O O   . PHE B 1 332 ? 8.635   30.980  107.753 1.00 35.96  ? 351 PHE B O   1 
ATOM   5361  C CB  . PHE B 1 332 ? 11.315  30.297  108.882 1.00 35.57  ? 351 PHE B CB  1 
ATOM   5362  C CG  . PHE B 1 332 ? 12.717  29.726  108.713 1.00 35.63  ? 351 PHE B CG  1 
ATOM   5363  C CD1 . PHE B 1 332 ? 13.478  30.010  107.598 1.00 36.55  ? 351 PHE B CD1 1 
ATOM   5364  C CD2 . PHE B 1 332 ? 13.261  28.902  109.691 1.00 35.11  ? 351 PHE B CD2 1 
ATOM   5365  C CE1 . PHE B 1 332 ? 14.736  29.496  107.449 1.00 37.11  ? 351 PHE B CE1 1 
ATOM   5366  C CE2 . PHE B 1 332 ? 14.524  28.372  109.552 1.00 35.17  ? 351 PHE B CE2 1 
ATOM   5367  C CZ  . PHE B 1 332 ? 15.268  28.664  108.430 1.00 36.22  ? 351 PHE B CZ  1 
ATOM   5368  N N   . ASP B 1 333 ? 9.214   33.041  108.361 1.00 38.94  ? 352 ASP B N   1 
ATOM   5369  C CA  . ASP B 1 333 ? 7.839   33.504  108.345 1.00 39.17  ? 352 ASP B CA  1 
ATOM   5370  C C   . ASP B 1 333 ? 7.557   34.456  107.196 1.00 40.41  ? 352 ASP B C   1 
ATOM   5371  O O   . ASP B 1 333 ? 6.388   34.775  106.965 1.00 41.37  ? 352 ASP B O   1 
ATOM   5372  C CB  . ASP B 1 333 ? 7.504   34.146  109.694 1.00 39.52  ? 352 ASP B CB  1 
ATOM   5373  C CG  . ASP B 1 333 ? 7.444   33.124  110.796 1.00 38.92  ? 352 ASP B CG  1 
ATOM   5374  O OD1 . ASP B 1 333 ? 7.048   31.955  110.487 1.00 38.24  ? 352 ASP B OD1 1 
ATOM   5375  O OD2 . ASP B 1 333 ? 7.831   33.464  111.958 1.00 39.31  ? 352 ASP B OD2 1 
ATOM   5376  N N   . LYS B 1 334 ? 8.559   34.825  106.429 1.00 37.45  ? 353 LYS B N   1 
ATOM   5377  C CA  . LYS B 1 334 ? 8.370   35.828  105.395 1.00 39.12  ? 353 LYS B CA  1 
ATOM   5378  C C   . LYS B 1 334 ? 7.725   35.231  104.161 1.00 38.85  ? 353 LYS B C   1 
ATOM   5379  O O   . LYS B 1 334 ? 8.198   34.208  103.674 1.00 38.32  ? 353 LYS B O   1 
ATOM   5380  C CB  . LYS B 1 334 ? 9.699   36.462  105.012 1.00 40.67  ? 353 LYS B CB  1 
ATOM   5381  C CG  . LYS B 1 334 ? 9.997   37.615  105.902 1.00 41.65  ? 353 LYS B CG  1 
ATOM   5382  C CD  . LYS B 1 334 ? 11.355  38.218  105.678 1.00 43.30  ? 353 LYS B CD  1 
ATOM   5383  C CE  . LYS B 1 334 ? 11.843  38.840  107.002 1.00 44.03  ? 353 LYS B CE  1 
ATOM   5384  N NZ  . LYS B 1 334 ? 13.330  38.823  107.162 1.00 44.53  ? 353 LYS B NZ  1 
ATOM   5385  N N   . PRO B 1 335 ? 6.696   35.868  103.600 1.00 39.36  ? 354 PRO B N   1 
ATOM   5386  C CA  . PRO B 1 335 ? 6.090   35.370  102.365 1.00 39.47  ? 354 PRO B CA  1 
ATOM   5387  C C   . PRO B 1 335 ? 7.130   35.002  101.327 1.00 39.72  ? 354 PRO B C   1 
ATOM   5388  O O   . PRO B 1 335 ? 7.999   35.804  100.994 1.00 40.76  ? 354 PRO B O   1 
ATOM   5389  C CB  . PRO B 1 335 ? 5.264   36.562  101.895 1.00 41.07  ? 354 PRO B CB  1 
ATOM   5390  C CG  . PRO B 1 335 ? 4.931   37.279  103.134 1.00 41.09  ? 354 PRO B CG  1 
ATOM   5391  C CD  . PRO B 1 335 ? 6.147   37.173  103.983 1.00 40.19  ? 354 PRO B CD  1 
ATOM   5392  N N   . LEU B 1 336 ? 7.015   33.789  100.776 1.00 38.70  ? 355 LEU B N   1 
ATOM   5393  C CA  . LEU B 1 336 ? 7.863   33.372  99.668  1.00 39.05  ? 355 LEU B CA  1 
ATOM   5394  C C   . LEU B 1 336 ? 7.089   33.297  98.355  1.00 39.83  ? 355 LEU B C   1 
ATOM   5395  O O   . LEU B 1 336 ? 7.398   34.045  97.411  1.00 41.24  ? 355 LEU B O   1 
ATOM   5396  C CB  . LEU B 1 336 ? 8.513   32.028  100.021 1.00 38.21  ? 355 LEU B CB  1 
ATOM   5397  C CG  . LEU B 1 336 ? 9.460   31.388  99.015  1.00 38.58  ? 355 LEU B CG  1 
ATOM   5398  C CD1 . LEU B 1 336 ? 10.694  32.213  98.803  1.00 39.31  ? 355 LEU B CD1 1 
ATOM   5399  C CD2 . LEU B 1 336 ? 9.807   30.000  99.551  1.00 37.70  ? 355 LEU B CD2 1 
ATOM   5400  N N   . GLY B 1 337 ? 6.100   32.401  98.262  1.00 40.05  ? 356 GLY B N   1 
ATOM   5401  C CA  . GLY B 1 337 ? 5.311   32.240  97.061  1.00 40.96  ? 356 GLY B CA  1 
ATOM   5402  C C   . GLY B 1 337 ? 5.947   31.314  96.039  1.00 41.29  ? 356 GLY B C   1 
ATOM   5403  O O   . GLY B 1 337 ? 7.115   30.935  96.127  1.00 41.04  ? 356 GLY B O   1 
ATOM   5404  N N   . LYS B 1 338 ? 5.148   30.964  95.022  1.00 40.88  ? 357 LYS B N   1 
ATOM   5405  C CA  . LYS B 1 338 ? 5.625   30.083  93.959  1.00 41.93  ? 357 LYS B CA  1 
ATOM   5406  C C   . LYS B 1 338 ? 6.861   30.691  93.306  1.00 42.28  ? 357 LYS B C   1 
ATOM   5407  O O   . LYS B 1 338 ? 6.888   31.909  93.066  1.00 43.12  ? 357 LYS B O   1 
ATOM   5408  C CB  . LYS B 1 338 ? 4.534   29.907  92.890  1.00 44.08  ? 357 LYS B CB  1 
ATOM   5409  N N   . PRO B 1 339 ? 7.867   29.892  92.951  1.00 40.02  ? 358 PRO B N   1 
ATOM   5410  C CA  . PRO B 1 339 ? 8.843   30.378  91.971  1.00 41.22  ? 358 PRO B CA  1 
ATOM   5411  C C   . PRO B 1 339 ? 8.092   30.950  90.783  1.00 42.78  ? 358 PRO B C   1 
ATOM   5412  O O   . PRO B 1 339 ? 7.070   30.403  90.365  1.00 44.17  ? 358 PRO B O   1 
ATOM   5413  C CB  . PRO B 1 339 ? 9.652   29.130  91.593  1.00 41.36  ? 358 PRO B CB  1 
ATOM   5414  C CG  . PRO B 1 339 ? 9.430   28.171  92.644  1.00 40.58  ? 358 PRO B CG  1 
ATOM   5415  C CD  . PRO B 1 339 ? 8.082   28.458  93.254  1.00 39.69  ? 358 PRO B CD  1 
ATOM   5416  N N   . VAL B 1 340 ? 8.559   32.104  90.300  1.00 43.00  ? 359 VAL B N   1 
ATOM   5417  C CA  . VAL B 1 340 ? 8.038   32.691  89.075  1.00 47.01  ? 359 VAL B CA  1 
ATOM   5418  C C   . VAL B 1 340 ? 8.997   32.473  87.918  1.00 47.80  ? 359 VAL B C   1 
ATOM   5419  O O   . VAL B 1 340 ? 8.658   32.812  86.772  1.00 50.91  ? 359 VAL B O   1 
ATOM   5420  C CB  . VAL B 1 340 ? 7.734   34.204  89.231  1.00 48.81  ? 359 VAL B CB  1 
ATOM   5421  C CG1 . VAL B 1 340 ? 6.737   34.450  90.362  1.00 48.21  ? 359 VAL B CG1 1 
ATOM   5422  C CG2 . VAL B 1 340 ? 9.001   35.034  89.468  1.00 47.34  ? 359 VAL B CG2 1 
ATOM   5423  N N   . GLY B 1 341 ? 10.177  31.917  88.177  1.00 46.21  ? 360 GLY B N   1 
ATOM   5424  C CA  . GLY B 1 341 ? 11.127  31.606  87.130  1.00 47.13  ? 360 GLY B CA  1 
ATOM   5425  C C   . GLY B 1 341 ? 11.984  30.432  87.552  1.00 45.21  ? 360 GLY B C   1 
ATOM   5426  O O   . GLY B 1 341 ? 12.019  30.036  88.725  1.00 43.82  ? 360 GLY B O   1 
ATOM   5427  N N   . GLU B 1 342 ? 12.647  29.838  86.571  1.00 46.76  ? 361 GLU B N   1 
ATOM   5428  C CA  . GLU B 1 342 ? 13.606  28.806  86.909  1.00 46.49  ? 361 GLU B CA  1 
ATOM   5429  C C   . GLU B 1 342 ? 14.861  29.468  87.455  1.00 46.33  ? 361 GLU B C   1 
ATOM   5430  O O   . GLU B 1 342 ? 15.060  30.687  87.337  1.00 47.07  ? 361 GLU B O   1 
ATOM   5431  C CB  . GLU B 1 342 ? 13.955  27.958  85.695  1.00 48.12  ? 361 GLU B CB  1 
ATOM   5432  C CG  . GLU B 1 342 ? 12.760  27.342  84.947  1.00 49.02  ? 361 GLU B CG  1 
ATOM   5433  C CD  . GLU B 1 342 ? 12.077  26.194  85.724  1.00 48.74  ? 361 GLU B CD  1 
ATOM   5434  O OE1 . GLU B 1 342 ? 10.812  26.126  85.640  1.00 47.80  ? 361 GLU B OE1 1 
ATOM   5435  O OE2 . GLU B 1 342 ? 12.789  25.378  86.413  1.00 49.84  ? 361 GLU B OE2 1 
ATOM   5436  N N   . MET B 1 343 ? 15.697  28.656  88.084  1.00 45.38  ? 362 MET B N   1 
ATOM   5437  C CA  . MET B 1 343 ? 17.015  29.101  88.490  1.00 45.83  ? 362 MET B CA  1 
ATOM   5438  C C   . MET B 1 343 ? 17.832  29.471  87.264  1.00 47.64  ? 362 MET B C   1 
ATOM   5439  O O   . MET B 1 343 ? 17.766  28.816  86.228  1.00 48.64  ? 362 MET B O   1 
ATOM   5440  C CB  . MET B 1 343 ? 17.731  27.997  89.265  1.00 45.27  ? 362 MET B CB  1 
ATOM   5441  C CG  . MET B 1 343 ? 19.252  28.228  89.388  1.00 45.47  ? 362 MET B CG  1 
ATOM   5442  S SD  . MET B 1 343 ? 20.062  27.240  90.699  1.00 45.19  ? 362 MET B SD  1 
ATOM   5443  C CE  . MET B 1 343 ? 20.143  25.669  89.833  1.00 46.88  ? 362 MET B CE  1 
ATOM   5444  N N   . VAL B 1 344 ? 18.617  30.519  87.396  1.00 44.27  ? 363 VAL B N   1 
ATOM   5445  C CA  . VAL B 1 344 ? 19.543  30.951  86.364  1.00 46.18  ? 363 VAL B CA  1 
ATOM   5446  C C   . VAL B 1 344 ? 20.944  30.824  86.926  1.00 46.62  ? 363 VAL B C   1 
ATOM   5447  O O   . VAL B 1 344 ? 21.178  31.093  88.107  1.00 45.53  ? 363 VAL B O   1 
ATOM   5448  C CB  . VAL B 1 344 ? 19.250  32.397  85.901  1.00 47.61  ? 363 VAL B CB  1 
ATOM   5449  C CG1 . VAL B 1 344 ? 20.244  32.839  84.832  1.00 50.02  ? 363 VAL B CG1 1 
ATOM   5450  C CG2 . VAL B 1 344 ? 17.810  32.475  85.420  1.00 48.36  ? 363 VAL B CG2 1 
ATOM   5451  N N   . ARG B 1 345 ? 21.876  30.421  86.078  1.00 47.30  ? 364 ARG B N   1 
ATOM   5452  C CA  . ARG B 1 345 ? 23.239  30.223  86.518  1.00 48.11  ? 364 ARG B CA  1 
ATOM   5453  C C   . ARG B 1 345 ? 24.185  30.893  85.557  1.00 49.98  ? 364 ARG B C   1 
ATOM   5454  O O   . ARG B 1 345 ? 24.095  30.676  84.351  1.00 51.50  ? 364 ARG B O   1 
ATOM   5455  C CB  . ARG B 1 345 ? 23.616  28.741  86.614  1.00 48.81  ? 364 ARG B CB  1 
ATOM   5456  C CG  . ARG B 1 345 ? 25.107  28.558  86.892  1.00 50.74  ? 364 ARG B CG  1 
ATOM   5457  C CD  . ARG B 1 345 ? 25.374  27.205  87.497  1.00 51.11  ? 364 ARG B CD  1 
ATOM   5458  N NE  . ARG B 1 345 ? 25.518  26.184  86.473  1.00 52.18  ? 364 ARG B NE  1 
ATOM   5459  C CZ  . ARG B 1 345 ? 26.626  25.984  85.788  1.00 53.96  ? 364 ARG B CZ  1 
ATOM   5460  N NH1 . ARG B 1 345 ? 27.683  26.768  85.949  1.00 55.09  ? 364 ARG B NH1 1 
ATOM   5461  N NH2 . ARG B 1 345 ? 26.677  24.971  84.932  1.00 54.53  ? 364 ARG B NH2 1 
ATOM   5462  N N   . ASP B 1 346 ? 25.127  31.632  86.099  1.00 52.67  ? 365 ASP B N   1 
ATOM   5463  C CA  . ASP B 1 346 ? 26.198  32.244  85.318  1.00 54.95  ? 365 ASP B CA  1 
ATOM   5464  C C   . ASP B 1 346 ? 27.495  31.995  86.083  1.00 54.92  ? 365 ASP B C   1 
ATOM   5465  O O   . ASP B 1 346 ? 27.830  32.736  87.011  1.00 54.36  ? 365 ASP B O   1 
ATOM   5466  C CB  . ASP B 1 346 ? 25.922  33.713  85.101  1.00 56.16  ? 365 ASP B CB  1 
ATOM   5467  C CG  . ASP B 1 346 ? 27.138  34.465  84.660  1.00 58.91  ? 365 ASP B CG  1 
ATOM   5468  O OD1 . ASP B 1 346 ? 27.940  33.887  83.874  1.00 60.27  ? 365 ASP B OD1 1 
ATOM   5469  O OD2 . ASP B 1 346 ? 27.269  35.643  85.096  1.00 59.67  ? 365 ASP B OD2 1 
ATOM   5470  N N   . GLY B 1 347 ? 28.203  30.928  85.693  1.00 54.14  ? 366 GLY B N   1 
ATOM   5471  C CA  . GLY B 1 347 ? 29.380  30.468  86.402  1.00 54.44  ? 366 GLY B CA  1 
ATOM   5472  C C   . GLY B 1 347 ? 28.962  29.907  87.738  1.00 52.84  ? 366 GLY B C   1 
ATOM   5473  O O   . GLY B 1 347 ? 28.116  29.007  87.781  1.00 52.46  ? 366 GLY B O   1 
ATOM   5474  N N   . TRP B 1 348 ? 29.531  30.452  88.825  1.00 49.68  ? 367 TRP B N   1 
ATOM   5475  C CA  . TRP B 1 348 ? 29.180  30.099  90.197  1.00 47.55  ? 367 TRP B CA  1 
ATOM   5476  C C   . TRP B 1 348 ? 28.058  30.962  90.764  1.00 45.83  ? 367 TRP B C   1 
ATOM   5477  O O   . TRP B 1 348 ? 27.673  30.772  91.925  1.00 43.82  ? 367 TRP B O   1 
ATOM   5478  C CB  . TRP B 1 348 ? 30.419  30.199  91.090  1.00 47.76  ? 367 TRP B CB  1 
ATOM   5479  C CG  . TRP B 1 348 ? 31.558  29.391  90.551  1.00 49.42  ? 367 TRP B CG  1 
ATOM   5480  C CD1 . TRP B 1 348 ? 32.695  29.852  89.958  1.00 51.39  ? 367 TRP B CD1 1 
ATOM   5481  C CD2 . TRP B 1 348 ? 31.661  27.966  90.542  1.00 49.70  ? 367 TRP B CD2 1 
ATOM   5482  N NE1 . TRP B 1 348 ? 33.508  28.800  89.582  1.00 52.78  ? 367 TRP B NE1 1 
ATOM   5483  C CE2 . TRP B 1 348 ? 32.894  27.631  89.931  1.00 51.63  ? 367 TRP B CE2 1 
ATOM   5484  C CE3 . TRP B 1 348 ? 30.829  26.939  90.984  1.00 48.50  ? 367 TRP B CE3 1 
ATOM   5485  C CZ2 . TRP B 1 348 ? 33.308  26.315  89.752  1.00 52.33  ? 367 TRP B CZ2 1 
ATOM   5486  C CZ3 . TRP B 1 348 ? 31.249  25.623  90.815  1.00 49.09  ? 367 TRP B CZ3 1 
ATOM   5487  C CH2 . TRP B 1 348 ? 32.479  25.327  90.208  1.00 50.84  ? 367 TRP B CH2 1 
ATOM   5488  N N   . LYS B 1 349 ? 27.506  31.890  89.982  1.00 48.11  ? 368 LYS B N   1 
ATOM   5489  C CA  . LYS B 1 349 ? 26.465  32.807  90.441  1.00 47.15  ? 368 LYS B CA  1 
ATOM   5490  C C   . LYS B 1 349 ? 25.084  32.255  90.079  1.00 46.03  ? 368 LYS B C   1 
ATOM   5491  O O   . LYS B 1 349 ? 24.841  31.890  88.926  1.00 47.41  ? 368 LYS B O   1 
ATOM   5492  C CB  . LYS B 1 349 ? 26.689  34.208  89.848  1.00 49.10  ? 368 LYS B CB  1 
ATOM   5493  N N   . LEU B 1 350 ? 24.187  32.204  91.066  1.00 46.68  ? 369 LEU B N   1 
ATOM   5494  C CA  . LEU B 1 350 ? 22.856  31.646  90.885  1.00 45.87  ? 369 LEU B CA  1 
ATOM   5495  C C   . LEU B 1 350 ? 21.786  32.629  91.329  1.00 45.44  ? 369 LEU B C   1 
ATOM   5496  O O   . LEU B 1 350 ? 21.918  33.259  92.379  1.00 44.75  ? 369 LEU B O   1 
ATOM   5497  C CB  . LEU B 1 350 ? 22.639  30.372  91.714  1.00 45.07  ? 369 LEU B CB  1 
ATOM   5498  C CG  . LEU B 1 350 ? 23.683  29.259  91.643  1.00 46.00  ? 369 LEU B CG  1 
ATOM   5499  C CD1 . LEU B 1 350 ? 23.441  28.243  92.766  1.00 44.85  ? 369 LEU B CD1 1 
ATOM   5500  C CD2 . LEU B 1 350 ? 23.628  28.650  90.236  1.00 47.89  ? 369 LEU B CD2 1 
ATOM   5501  N N   . SER B 1 351 ? 20.699  32.718  90.565  1.00 46.64  ? 370 SER B N   1 
ATOM   5502  C CA  . SER B 1 351 ? 19.592  33.600  90.897  1.00 46.34  ? 370 SER B CA  1 
ATOM   5503  C C   . SER B 1 351 ? 18.286  32.842  90.753  1.00 45.42  ? 370 SER B C   1 
ATOM   5504  O O   . SER B 1 351 ? 18.170  31.930  89.930  1.00 45.74  ? 370 SER B O   1 
ATOM   5505  C CB  . SER B 1 351 ? 19.556  34.870  89.977  1.00 48.17  ? 370 SER B CB  1 
ATOM   5506  O OG  . SER B 1 351 ? 19.222  34.549  88.630  1.00 50.00  ? 370 SER B OG  1 
ATOM   5507  N N   . ARG B 1 352 ? 17.301  33.242  91.551  1.00 45.78  ? 371 ARG B N   1 
ATOM   5508  C CA  . ARG B 1 352 ? 15.957  32.696  91.448  1.00 45.15  ? 371 ARG B CA  1 
ATOM   5509  C C   . ARG B 1 352 ? 14.979  33.810  91.775  1.00 44.96  ? 371 ARG B C   1 
ATOM   5510  O O   . ARG B 1 352 ? 15.275  34.707  92.559  1.00 44.93  ? 371 ARG B O   1 
ATOM   5511  C CB  . ARG B 1 352 ? 15.768  31.483  92.373  1.00 44.33  ? 371 ARG B CB  1 
ATOM   5512  C CG  . ARG B 1 352 ? 14.535  30.657  92.057  1.00 43.41  ? 371 ARG B CG  1 
ATOM   5513  C CD  . ARG B 1 352 ? 14.714  29.863  90.793  1.00 44.23  ? 371 ARG B CD  1 
ATOM   5514  N NE  . ARG B 1 352 ? 13.673  28.850  90.713  1.00 43.48  ? 371 ARG B NE  1 
ATOM   5515  C CZ  . ARG B 1 352 ? 13.600  27.777  91.496  1.00 42.39  ? 371 ARG B CZ  1 
ATOM   5516  N NH1 . ARG B 1 352 ? 14.519  27.522  92.418  1.00 41.89  ? 371 ARG B NH1 1 
ATOM   5517  N NH2 . ARG B 1 352 ? 12.571  26.950  91.359  1.00 42.24  ? 371 ARG B NH2 1 
ATOM   5518  N N   . GLU B 1 353 ? 13.836  33.782  91.115  1.00 45.07  ? 372 GLU B N   1 
ATOM   5519  C CA  . GLU B 1 353 ? 12.770  34.717  91.391  1.00 45.04  ? 372 GLU B CA  1 
ATOM   5520  C C   . GLU B 1 353 ? 11.562  33.966  91.938  1.00 44.01  ? 372 GLU B C   1 
ATOM   5521  O O   . GLU B 1 353 ? 11.070  33.019  91.322  1.00 43.96  ? 372 GLU B O   1 
ATOM   5522  C CB  . GLU B 1 353 ? 12.387  35.505  90.130  1.00 46.82  ? 372 GLU B CB  1 
ATOM   5523  C CG  . GLU B 1 353 ? 13.516  36.376  89.551  1.00 49.27  ? 372 GLU B CG  1 
ATOM   5524  C CD  . GLU B 1 353 ? 14.071  37.406  90.539  1.00 50.11  ? 372 GLU B CD  1 
ATOM   5525  O OE1 . GLU B 1 353 ? 13.255  38.110  91.206  1.00 49.63  ? 372 GLU B OE1 1 
ATOM   5526  O OE2 . GLU B 1 353 ? 15.335  37.472  90.666  1.00 51.32  ? 372 GLU B OE2 1 
ATOM   5527  N N   . TYR B 1 354 ? 11.055  34.442  93.059  1.00 43.84  ? 373 TYR B N   1 
ATOM   5528  C CA  . TYR B 1 354 ? 9.808   34.008  93.662  1.00 42.99  ? 373 TYR B CA  1 
ATOM   5529  C C   . TYR B 1 354 ? 8.778   35.146  93.622  1.00 43.62  ? 373 TYR B C   1 
ATOM   5530  O O   . TYR B 1 354 ? 9.120   36.314  93.483  1.00 44.94  ? 373 TYR B O   1 
ATOM   5531  C CB  . TYR B 1 354 ? 10.090  33.542  95.100  1.00 41.63  ? 373 TYR B CB  1 
ATOM   5532  C CG  . TYR B 1 354 ? 10.907  32.249  95.208  1.00 40.62  ? 373 TYR B CG  1 
ATOM   5533  C CD1 . TYR B 1 354 ? 12.296  32.222  95.016  1.00 41.10  ? 373 TYR B CD1 1 
ATOM   5534  C CD2 . TYR B 1 354 ? 10.281  31.058  95.544  1.00 39.62  ? 373 TYR B CD2 1 
ATOM   5535  C CE1 . TYR B 1 354 ? 13.010  31.044  95.149  1.00 40.72  ? 373 TYR B CE1 1 
ATOM   5536  C CE2 . TYR B 1 354 ? 10.988  29.895  95.681  1.00 39.34  ? 373 TYR B CE2 1 
ATOM   5537  C CZ  . TYR B 1 354 ? 12.345  29.893  95.478  1.00 39.56  ? 373 TYR B CZ  1 
ATOM   5538  O OH  . TYR B 1 354 ? 13.005  28.688  95.624  1.00 39.36  ? 373 TYR B OH  1 
ATOM   5539  N N   . LYS B 1 355 ? 7.498   34.778  93.729  1.00 40.96  ? 374 LYS B N   1 
ATOM   5540  C CA  . LYS B 1 355 ? 6.439   35.771  93.745  1.00 44.10  ? 374 LYS B CA  1 
ATOM   5541  C C   . LYS B 1 355 ? 6.748   36.877  94.746  1.00 43.50  ? 374 LYS B C   1 
ATOM   5542  O O   . LYS B 1 355 ? 6.502   38.049  94.474  1.00 46.19  ? 374 LYS B O   1 
ATOM   5543  C CB  . LYS B 1 355 ? 5.090   35.118  94.055  1.00 45.37  ? 374 LYS B CB  1 
ATOM   5544  N N   . HIS B 1 356 ? 7.329   36.540  95.891  1.00 41.99  ? 375 HIS B N   1 
ATOM   5545  C CA  . HIS B 1 356 ? 7.592   37.534  96.929  1.00 42.51  ? 375 HIS B CA  1 
ATOM   5546  C C   . HIS B 1 356 ? 9.068   37.626  97.317  1.00 42.95  ? 375 HIS B C   1 
ATOM   5547  O O   . HIS B 1 356 ? 9.383   38.119  98.401  1.00 42.24  ? 375 HIS B O   1 
ATOM   5548  C CB  . HIS B 1 356 ? 6.736   37.238  98.173  1.00 41.38  ? 375 HIS B CB  1 
ATOM   5549  C CG  . HIS B 1 356 ? 5.279   37.083  97.859  1.00 42.42  ? 375 HIS B CG  1 
ATOM   5550  N ND1 . HIS B 1 356 ? 4.477   36.130  98.453  1.00 42.08  ? 375 HIS B ND1 1 
ATOM   5551  C CD2 . HIS B 1 356 ? 4.480   37.753  96.988  1.00 45.61  ? 375 HIS B CD2 1 
ATOM   5552  C CE1 . HIS B 1 356 ? 3.254   36.209  97.943  1.00 44.67  ? 375 HIS B CE1 1 
ATOM   5553  N NE2 . HIS B 1 356 ? 3.224   37.204  97.078  1.00 46.46  ? 375 HIS B NE2 1 
ATOM   5554  N N   . ALA B 1 357 ? 9.996   37.192  96.469  1.00 42.61  ? 376 ALA B N   1 
ATOM   5555  C CA  . ALA B 1 357 ? 11.390  37.395  96.846  1.00 43.25  ? 376 ALA B CA  1 
ATOM   5556  C C   . ALA B 1 357 ? 12.302  37.164  95.661  1.00 45.31  ? 376 ALA B C   1 
ATOM   5557  O O   . ALA B 1 357 ? 11.967  36.423  94.731  1.00 45.03  ? 376 ALA B O   1 
ATOM   5558  C CB  . ALA B 1 357 ? 11.815  36.455  97.993  1.00 41.67  ? 376 ALA B CB  1 
ATOM   5559  N N   . SER B 1 358 ? 13.485  37.778  95.738  1.00 43.79  ? 377 SER B N   1 
ATOM   5560  C CA  . SER B 1 358 ? 14.558  37.590  94.772  1.00 45.19  ? 377 SER B CA  1 
ATOM   5561  C C   . SER B 1 358 ? 15.778  37.036  95.484  1.00 45.40  ? 377 SER B C   1 
ATOM   5562  O O   . SER B 1 358 ? 16.191  37.576  96.506  1.00 45.66  ? 377 SER B O   1 
ATOM   5563  C CB  . SER B 1 358 ? 14.925  38.913  94.093  1.00 47.54  ? 377 SER B CB  1 
ATOM   5564  O OG  . SER B 1 358 ? 13.906  39.334  93.208  1.00 48.25  ? 377 SER B OG  1 
ATOM   5565  N N   . VAL B 1 359 ? 16.360  35.974  94.941  1.00 45.01  ? 378 VAL B N   1 
ATOM   5566  C CA  . VAL B 1 359 ? 17.485  35.279  95.547  1.00 45.53  ? 378 VAL B CA  1 
ATOM   5567  C C   . VAL B 1 359 ? 18.663  35.349  94.589  1.00 46.63  ? 378 VAL B C   1 
ATOM   5568  O O   . VAL B 1 359 ? 18.540  35.004  93.411  1.00 45.47  ? 378 VAL B O   1 
ATOM   5569  C CB  . VAL B 1 359 ? 17.143  33.809  95.867  1.00 42.10  ? 378 VAL B CB  1 
ATOM   5570  C CG1 . VAL B 1 359 ? 18.374  33.072  96.481  1.00 40.65  ? 378 VAL B CG1 1 
ATOM   5571  C CG2 . VAL B 1 359 ? 15.885  33.723  96.762  1.00 40.17  ? 378 VAL B CG2 1 
ATOM   5572  N N   . ARG B 1 360 ? 19.802  35.779  95.100  1.00 43.98  ? 379 ARG B N   1 
ATOM   5573  C CA  . ARG B 1 360 ? 21.074  35.777  94.391  1.00 45.35  ? 379 ARG B CA  1 
ATOM   5574  C C   . ARG B 1 360 ? 22.098  35.199  95.357  1.00 45.24  ? 379 ARG B C   1 
ATOM   5575  O O   . ARG B 1 360 ? 22.173  35.632  96.514  1.00 45.43  ? 379 ARG B O   1 
ATOM   5576  C CB  . ARG B 1 360 ? 21.467  37.201  93.925  1.00 48.51  ? 379 ARG B CB  1 
ATOM   5577  N N   . VAL B 1 361 ? 22.846  34.197  94.907  1.00 45.98  ? 380 VAL B N   1 
ATOM   5578  C CA  . VAL B 1 361 ? 23.978  33.683  95.663  1.00 46.22  ? 380 VAL B CA  1 
ATOM   5579  C C   . VAL B 1 361 ? 25.166  33.523  94.722  1.00 46.07  ? 380 VAL B C   1 
ATOM   5580  O O   . VAL B 1 361 ? 25.006  33.246  93.531  1.00 45.19  ? 380 VAL B O   1 
ATOM   5581  C CB  . VAL B 1 361 ? 23.651  32.340  96.371  1.00 43.64  ? 380 VAL B CB  1 
ATOM   5582  C CG1 . VAL B 1 361 ? 23.181  31.318  95.398  1.00 40.12  ? 380 VAL B CG1 1 
ATOM   5583  C CG2 . VAL B 1 361 ? 24.874  31.810  97.108  1.00 43.66  ? 380 VAL B CG2 1 
ATOM   5584  N N   . ASP B 1 362 ? 26.364  33.727  95.263  1.00 46.58  ? 381 ASP B N   1 
ATOM   5585  C CA  . ASP B 1 362 ? 27.617  33.459  94.567  1.00 46.49  ? 381 ASP B CA  1 
ATOM   5586  C C   . ASP B 1 362 ? 28.347  32.355  95.319  1.00 44.82  ? 381 ASP B C   1 
ATOM   5587  O O   . ASP B 1 362 ? 28.763  32.554  96.470  1.00 45.68  ? 381 ASP B O   1 
ATOM   5588  C CB  . ASP B 1 362 ? 28.491  34.712  94.502  1.00 48.90  ? 381 ASP B CB  1 
ATOM   5589  C CG  . ASP B 1 362 ? 29.807  34.491  93.757  1.00 49.70  ? 381 ASP B CG  1 
ATOM   5590  O OD1 . ASP B 1 362 ? 30.405  33.394  93.791  1.00 48.30  ? 381 ASP B OD1 1 
ATOM   5591  O OD2 . ASP B 1 362 ? 30.275  35.469  93.150  1.00 51.78  ? 381 ASP B OD2 1 
ATOM   5592  N N   . LEU B 1 363 ? 28.539  31.213  94.652  1.00 49.64  ? 382 LEU B N   1 
ATOM   5593  C CA  . LEU B 1 363 ? 29.168  30.059  95.288  1.00 47.82  ? 382 LEU B CA  1 
ATOM   5594  C C   . LEU B 1 363 ? 30.689  30.187  95.389  1.00 49.50  ? 382 LEU B C   1 
ATOM   5595  O O   . LEU B 1 363 ? 31.284  29.463  96.196  1.00 48.48  ? 382 LEU B O   1 
ATOM   5596  C CB  . LEU B 1 363 ? 28.784  28.778  94.535  1.00 44.73  ? 382 LEU B CB  1 
ATOM   5597  C CG  . LEU B 1 363 ? 27.268  28.520  94.504  1.00 42.56  ? 382 LEU B CG  1 
ATOM   5598  C CD1 . LEU B 1 363 ? 26.908  27.319  93.658  1.00 39.32  ? 382 LEU B CD1 1 
ATOM   5599  C CD2 . LEU B 1 363 ? 26.643  28.372  95.909  1.00 41.30  ? 382 LEU B CD2 1 
ATOM   5600  N N   . GLU B 1 364 ? 31.328  31.076  94.611  1.00 47.00  ? 383 GLU B N   1 
ATOM   5601  C CA  . GLU B 1 364 ? 32.764  31.319  94.785  1.00 48.49  ? 383 GLU B CA  1 
ATOM   5602  C C   . GLU B 1 364 ? 33.022  32.171  96.029  1.00 49.78  ? 383 GLU B C   1 
ATOM   5603  O O   . GLU B 1 364 ? 33.755  31.781  96.943  1.00 49.17  ? 383 GLU B O   1 
ATOM   5604  C CB  . GLU B 1 364 ? 33.362  32.017  93.551  1.00 49.97  ? 383 GLU B CB  1 
ATOM   5605  N N   . SER B 1 365 ? 32.422  33.361  96.078  1.00 48.57  ? 384 SER B N   1 
ATOM   5606  C CA  . SER B 1 365 ? 32.730  34.293  97.154  1.00 49.21  ? 384 SER B CA  1 
ATOM   5607  C C   . SER B 1 365 ? 31.953  34.017  98.427  1.00 48.47  ? 384 SER B C   1 
ATOM   5608  O O   . SER B 1 365 ? 32.351  34.512  99.480  1.00 48.08  ? 384 SER B O   1 
ATOM   5609  C CB  . SER B 1 365 ? 32.430  35.724  96.706  1.00 50.90  ? 384 SER B CB  1 
ATOM   5610  O OG  . SER B 1 365 ? 31.048  35.860  96.432  1.00 50.90  ? 384 SER B OG  1 
ATOM   5611  N N   . LYS B 1 366 ? 30.851  33.281  98.354  1.00 48.46  ? 385 LYS B N   1 
ATOM   5612  C CA  . LYS B 1 366 ? 29.976  32.981  99.482  1.00 48.68  ? 385 LYS B CA  1 
ATOM   5613  C C   . LYS B 1 366 ? 29.059  34.149  99.806  1.00 49.28  ? 385 LYS B C   1 
ATOM   5614  O O   . LYS B 1 366 ? 28.452  34.185  100.894 1.00 47.86  ? 385 LYS B O   1 
ATOM   5615  C CB  . LYS B 1 366 ? 30.769  32.584  100.728 1.00 48.13  ? 385 LYS B CB  1 
ATOM   5616  C CG  . LYS B 1 366 ? 31.876  31.584  100.442 1.00 48.25  ? 385 LYS B CG  1 
ATOM   5617  C CD  . LYS B 1 366 ? 31.303  30.266  99.947  1.00 47.15  ? 385 LYS B CD  1 
ATOM   5618  C CE  . LYS B 1 366 ? 32.394  29.267  99.624  1.00 45.90  ? 385 LYS B CE  1 
ATOM   5619  N NZ  . LYS B 1 366 ? 32.931  29.425  98.227  1.00 46.62  ? 385 LYS B NZ  1 
ATOM   5620  N N   . GLU B 1 367 ? 28.925  35.099  98.876  1.00 48.56  ? 386 GLU B N   1 
ATOM   5621  C CA  . GLU B 1 367 ? 28.013  36.223  99.063  1.00 49.09  ? 386 GLU B CA  1 
ATOM   5622  C C   . GLU B 1 367 ? 26.598  35.806  98.667  1.00 48.28  ? 386 GLU B C   1 
ATOM   5623  O O   . GLU B 1 367 ? 26.404  35.012  97.738  1.00 48.75  ? 386 GLU B O   1 
ATOM   5624  C CB  . GLU B 1 367 ? 28.479  37.432  98.244  1.00 51.37  ? 386 GLU B CB  1 
ATOM   5625  N N   . ALA B 1 368 ? 25.609  36.331  99.379  1.00 48.49  ? 387 ALA B N   1 
ATOM   5626  C CA  . ALA B 1 368 ? 24.229  36.011  99.087  1.00 47.43  ? 387 ALA B CA  1 
ATOM   5627  C C   . ALA B 1 368 ? 23.337  37.203  99.392  1.00 46.58  ? 387 ALA B C   1 
ATOM   5628  O O   . ALA B 1 368 ? 23.596  37.984  100.323 1.00 45.59  ? 387 ALA B O   1 
ATOM   5629  C CB  . ALA B 1 368 ? 23.744  34.816  99.900  1.00 44.77  ? 387 ALA B CB  1 
ATOM   5630  N N   . GLU B 1 369 ? 22.269  37.331  98.614  1.00 45.56  ? 388 GLU B N   1 
ATOM   5631  C CA  . GLU B 1 369 ? 21.273  38.352  98.890  1.00 45.16  ? 388 GLU B CA  1 
ATOM   5632  C C   . GLU B 1 369 ? 19.911  37.691  98.762  1.00 42.85  ? 388 GLU B C   1 
ATOM   5633  O O   . GLU B 1 369 ? 19.679  36.911  97.848  1.00 43.69  ? 388 GLU B O   1 
ATOM   5634  C CB  . GLU B 1 369 ? 21.429  39.574  97.947  1.00 48.92  ? 388 GLU B CB  1 
ATOM   5635  N N   . ILE B 1 370 ? 19.027  37.997  99.703  1.00 46.76  ? 389 ILE B N   1 
ATOM   5636  C CA  . ILE B 1 370 ? 17.612  37.677  99.583  1.00 45.28  ? 389 ILE B CA  1 
ATOM   5637  C C   . ILE B 1 370 ? 16.810  38.949  99.796  1.00 45.60  ? 389 ILE B C   1 
ATOM   5638  O O   . ILE B 1 370 ? 16.719  39.428  100.927 1.00 44.24  ? 389 ILE B O   1 
ATOM   5639  C CB  . ILE B 1 370 ? 17.169  36.609  100.596 1.00 41.53  ? 389 ILE B CB  1 
ATOM   5640  C CG1 . ILE B 1 370 ? 18.025  35.368  100.459 1.00 41.27  ? 389 ILE B CG1 1 
ATOM   5641  C CG2 . ILE B 1 370 ? 15.638  36.360  100.454 1.00 40.35  ? 389 ILE B CG2 1 
ATOM   5642  C CD1 . ILE B 1 370 ? 17.657  34.374  101.490 1.00 36.53  ? 389 ILE B CD1 1 
ATOM   5643  N N   . ARG B 1 371 ? 16.205  39.480  98.732  1.00 45.80  ? 390 ARG B N   1 
ATOM   5644  C CA  . ARG B 1 371 ? 15.335  40.650  98.823  1.00 46.38  ? 390 ARG B CA  1 
ATOM   5645  C C   . ARG B 1 371 ? 13.913  40.126  98.949  1.00 44.22  ? 390 ARG B C   1 
ATOM   5646  O O   . ARG B 1 371 ? 13.424  39.448  98.042  1.00 45.35  ? 390 ARG B O   1 
ATOM   5647  C CB  . ARG B 1 371 ? 15.486  41.578  97.613  1.00 50.10  ? 390 ARG B CB  1 
ATOM   5648  N N   . TRP B 1 372 ? 13.263  40.410  100.072 1.00 48.69  ? 391 TRP B N   1 
ATOM   5649  C CA  . TRP B 1 372 ? 11.855  40.064  100.266 1.00 47.28  ? 391 TRP B CA  1 
ATOM   5650  C C   . TRP B 1 372 ? 10.938  41.198  99.782  1.00 48.96  ? 391 TRP B C   1 
ATOM   5651  O O   . TRP B 1 372 ? 11.064  42.340  100.236 1.00 49.82  ? 391 TRP B O   1 
ATOM   5652  C CB  . TRP B 1 372 ? 11.616  39.758  101.746 1.00 43.53  ? 391 TRP B CB  1 
ATOM   5653  C CG  . TRP B 1 372 ? 12.530  38.643  102.364 1.00 41.35  ? 391 TRP B CG  1 
ATOM   5654  C CD1 . TRP B 1 372 ? 13.659  38.814  103.119 1.00 40.73  ? 391 TRP B CD1 1 
ATOM   5655  C CD2 . TRP B 1 372 ? 12.326  37.221  102.292 1.00 39.18  ? 391 TRP B CD2 1 
ATOM   5656  N NE1 . TRP B 1 372 ? 14.165  37.591  103.508 1.00 38.76  ? 391 TRP B NE1 1 
ATOM   5657  C CE2 . TRP B 1 372 ? 13.368  36.604  103.014 1.00 37.38  ? 391 TRP B CE2 1 
ATOM   5658  C CE3 . TRP B 1 372 ? 11.368  36.424  101.684 1.00 38.73  ? 391 TRP B CE3 1 
ATOM   5659  C CZ2 . TRP B 1 372 ? 13.493  35.213  103.133 1.00 35.49  ? 391 TRP B CZ2 1 
ATOM   5660  C CZ3 . TRP B 1 372 ? 11.473  35.040  101.804 1.00 36.31  ? 391 TRP B CZ3 1 
ATOM   5661  C CH2 . TRP B 1 372 ? 12.538  34.444  102.527 1.00 35.15  ? 391 TRP B CH2 1 
ATOM   5662  N N   . ARG B 1 373 ? 10.012  40.869  98.872  1.00 46.41  ? 392 ARG B N   1 
ATOM   5663  C CA  . ARG B 1 373 ? 9.225   41.846  98.136  1.00 48.47  ? 392 ARG B CA  1 
ATOM   5664  C C   . ARG B 1 373 ? 7.713   41.626  98.351  1.00 48.37  ? 392 ARG B C   1 
ATOM   5665  O O   . ARG B 1 373 ? 7.200   41.725  99.482  1.00 47.32  ? 392 ARG B O   1 
ATOM   5666  C CB  . ARG B 1 373 ? 9.570   41.774  96.636  1.00 51.75  ? 392 ARG B CB  1 
ATOM   5667  N N   . GLU C 1 18  ? 36.094  -20.221 140.957 1.00 50.99  ? 37  GLU C N   1 
ATOM   5668  C CA  . GLU C 1 18  ? 34.743  -20.733 140.704 1.00 50.34  ? 37  GLU C CA  1 
ATOM   5669  C C   . GLU C 1 18  ? 34.010  -20.966 142.040 1.00 48.24  ? 37  GLU C C   1 
ATOM   5670  O O   . GLU C 1 18  ? 33.635  -20.019 142.728 1.00 46.88  ? 37  GLU C O   1 
ATOM   5671  C CB  . GLU C 1 18  ? 34.780  -22.047 139.875 1.00 51.70  ? 37  GLU C CB  1 
ATOM   5672  N N   . SER C 1 19  ? 33.818  -22.241 142.394 1.00 54.34  ? 38  SER C N   1 
ATOM   5673  C CA  . SER C 1 19  ? 33.006  -22.629 143.546 1.00 53.11  ? 38  SER C CA  1 
ATOM   5674  C C   . SER C 1 19  ? 33.518  -22.062 144.873 1.00 51.50  ? 38  SER C C   1 
ATOM   5675  O O   . SER C 1 19  ? 32.776  -22.089 145.877 1.00 51.46  ? 38  SER C O   1 
ATOM   5676  C CB  . SER C 1 19  ? 32.963  -24.154 143.587 1.00 53.57  ? 38  SER C CB  1 
ATOM   5677  O OG  . SER C 1 19  ? 34.256  -24.628 143.937 1.00 53.66  ? 38  SER C OG  1 
ATOM   5678  N N   . HIS C 1 20  ? 34.743  -21.543 144.931 1.00 43.92  ? 39  HIS C N   1 
ATOM   5679  C CA  . HIS C 1 20  ? 35.204  -20.937 146.152 1.00 43.03  ? 39  HIS C CA  1 
ATOM   5680  C C   . HIS C 1 20  ? 35.125  -19.431 146.124 1.00 42.44  ? 39  HIS C C   1 
ATOM   5681  O O   . HIS C 1 20  ? 35.633  -18.791 147.046 1.00 42.27  ? 39  HIS C O   1 
ATOM   5682  C CB  . HIS C 1 20  ? 36.627  -21.340 146.426 1.00 43.40  ? 39  HIS C CB  1 
ATOM   5683  C CG  . HIS C 1 20  ? 37.623  -20.837 145.427 1.00 44.34  ? 39  HIS C CG  1 
ATOM   5684  N ND1 . HIS C 1 20  ? 37.574  -21.180 144.097 1.00 45.23  ? 39  HIS C ND1 1 
ATOM   5685  C CD2 . HIS C 1 20  ? 38.765  -20.130 145.592 1.00 45.32  ? 39  HIS C CD2 1 
ATOM   5686  C CE1 . HIS C 1 20  ? 38.625  -20.673 143.477 1.00 45.97  ? 39  HIS C CE1 1 
ATOM   5687  N NE2 . HIS C 1 20  ? 39.366  -20.039 144.364 1.00 45.88  ? 39  HIS C NE2 1 
ATOM   5688  N N   . TYR C 1 21  ? 34.512  -18.857 145.091 1.00 41.76  ? 40  TYR C N   1 
ATOM   5689  C CA  . TYR C 1 21  ? 34.391  -17.413 144.963 1.00 41.73  ? 40  TYR C CA  1 
ATOM   5690  C C   . TYR C 1 21  ? 33.234  -16.904 145.811 1.00 41.42  ? 40  TYR C C   1 
ATOM   5691  O O   . TYR C 1 21  ? 32.235  -17.596 145.987 1.00 41.50  ? 40  TYR C O   1 
ATOM   5692  C CB  . TYR C 1 21  ? 34.123  -17.007 143.525 1.00 41.96  ? 40  TYR C CB  1 
ATOM   5693  C CG  . TYR C 1 21  ? 35.324  -16.907 142.600 1.00 42.20  ? 40  TYR C CG  1 
ATOM   5694  C CD1 . TYR C 1 21  ? 36.549  -17.478 142.927 1.00 42.42  ? 40  TYR C CD1 1 
ATOM   5695  C CD2 . TYR C 1 21  ? 35.211  -16.233 141.380 1.00 42.38  ? 40  TYR C CD2 1 
ATOM   5696  C CE1 . TYR C 1 21  ? 37.629  -17.392 142.065 1.00 42.91  ? 40  TYR C CE1 1 
ATOM   5697  C CE2 . TYR C 1 21  ? 36.281  -16.135 140.524 1.00 42.77  ? 40  TYR C CE2 1 
ATOM   5698  C CZ  . TYR C 1 21  ? 37.483  -16.723 140.857 1.00 43.08  ? 40  TYR C CZ  1 
ATOM   5699  O OH  . TYR C 1 21  ? 38.543  -16.610 139.986 1.00 43.76  ? 40  TYR C OH  1 
ATOM   5700  N N   . PRO C 1 22  ? 33.318  -15.690 146.330 1.00 40.18  ? 41  PRO C N   1 
ATOM   5701  C CA  . PRO C 1 22  ? 32.115  -15.097 146.924 1.00 40.12  ? 41  PRO C CA  1 
ATOM   5702  C C   . PRO C 1 22  ? 30.976  -15.155 145.906 1.00 40.52  ? 41  PRO C C   1 
ATOM   5703  O O   . PRO C 1 22  ? 31.170  -14.983 144.694 1.00 40.93  ? 41  PRO C O   1 
ATOM   5704  C CB  . PRO C 1 22  ? 32.529  -13.653 147.259 1.00 40.04  ? 41  PRO C CB  1 
ATOM   5705  C CG  . PRO C 1 22  ? 34.006  -13.621 147.161 1.00 40.29  ? 41  PRO C CG  1 
ATOM   5706  C CD  . PRO C 1 22  ? 34.419  -14.709 146.207 1.00 40.38  ? 41  PRO C CD  1 
ATOM   5707  N N   . GLU C 1 23  ? 29.781  -15.407 146.413 1.00 43.58  ? 42  GLU C N   1 
ATOM   5708  C CA  . GLU C 1 23  ? 28.593  -15.422 145.590 1.00 44.23  ? 42  GLU C CA  1 
ATOM   5709  C C   . GLU C 1 23  ? 28.301  -14.026 145.075 1.00 44.64  ? 42  GLU C C   1 
ATOM   5710  O O   . GLU C 1 23  ? 28.152  -13.077 145.845 1.00 45.02  ? 42  GLU C O   1 
ATOM   5711  C CB  . GLU C 1 23  ? 27.436  -15.951 146.402 1.00 45.21  ? 42  GLU C CB  1 
ATOM   5712  C CG  . GLU C 1 23  ? 26.225  -16.373 145.609 1.00 47.11  ? 42  GLU C CG  1 
ATOM   5713  C CD  . GLU C 1 23  ? 25.005  -16.392 146.515 1.00 48.39  ? 42  GLU C CD  1 
ATOM   5714  O OE1 . GLU C 1 23  ? 24.706  -15.327 147.139 1.00 48.00  ? 42  GLU C OE1 1 
ATOM   5715  O OE2 . GLU C 1 23  ? 24.390  -17.464 146.661 1.00 50.89  ? 42  GLU C OE2 1 
ATOM   5716  N N   . PHE C 1 24  ? 28.213  -13.920 143.765 1.00 41.01  ? 43  PHE C N   1 
ATOM   5717  C CA  . PHE C 1 24  ? 28.127  -12.674 143.060 1.00 40.94  ? 43  PHE C CA  1 
ATOM   5718  C C   . PHE C 1 24  ? 26.712  -12.495 142.540 1.00 41.94  ? 43  PHE C C   1 
ATOM   5719  O O   . PHE C 1 24  ? 26.028  -13.467 142.161 1.00 42.78  ? 43  PHE C O   1 
ATOM   5720  C CB  . PHE C 1 24  ? 29.128  -12.622 141.898 1.00 40.85  ? 43  PHE C CB  1 
ATOM   5721  C CG  . PHE C 1 24  ? 29.157  -11.287 141.221 1.00 40.68  ? 43  PHE C CG  1 
ATOM   5722  C CD1 . PHE C 1 24  ? 29.882  -10.238 141.749 1.00 40.36  ? 43  PHE C CD1 1 
ATOM   5723  C CD2 . PHE C 1 24  ? 28.391  -11.079 140.094 1.00 41.77  ? 43  PHE C CD2 1 
ATOM   5724  C CE1 . PHE C 1 24  ? 29.843  -8.973  141.132 1.00 40.87  ? 43  PHE C CE1 1 
ATOM   5725  C CE2 . PHE C 1 24  ? 28.351  -9.861  139.467 1.00 41.94  ? 43  PHE C CE2 1 
ATOM   5726  C CZ  . PHE C 1 24  ? 29.080  -8.804  139.980 1.00 41.61  ? 43  PHE C CZ  1 
ATOM   5727  N N   . SER C 1 25  ? 26.291  -11.225 142.516 1.00 40.02  ? 44  SER C N   1 
ATOM   5728  C CA  . SER C 1 25  ? 24.984  -10.855 142.016 1.00 41.25  ? 44  SER C CA  1 
ATOM   5729  C C   . SER C 1 25  ? 25.067  -9.451  141.441 1.00 41.18  ? 44  SER C C   1 
ATOM   5730  O O   . SER C 1 25  ? 25.813  -8.580  141.933 1.00 40.75  ? 44  SER C O   1 
ATOM   5731  C CB  . SER C 1 25  ? 23.942  -10.920 143.121 1.00 42.58  ? 44  SER C CB  1 
ATOM   5732  O OG  . SER C 1 25  ? 22.715  -10.464 142.653 1.00 43.84  ? 44  SER C OG  1 
ATOM   5733  N N   . TRP C 1 26  ? 24.291  -9.238  140.393 1.00 41.40  ? 45  TRP C N   1 
ATOM   5734  C CA  . TRP C 1 26  ? 24.118  -7.916  139.825 1.00 41.76  ? 45  TRP C CA  1 
ATOM   5735  C C   . TRP C 1 26  ? 22.891  -7.215  140.375 1.00 42.36  ? 45  TRP C C   1 
ATOM   5736  O O   . TRP C 1 26  ? 22.585  -6.099  139.931 1.00 43.22  ? 45  TRP C O   1 
ATOM   5737  C CB  . TRP C 1 26  ? 23.984  -8.011  138.318 1.00 42.36  ? 45  TRP C CB  1 
ATOM   5738  C CG  . TRP C 1 26  ? 25.214  -8.307  137.528 1.00 41.80  ? 45  TRP C CG  1 
ATOM   5739  C CD1 . TRP C 1 26  ? 25.430  -9.398  136.761 1.00 42.21  ? 45  TRP C CD1 1 
ATOM   5740  C CD2 . TRP C 1 26  ? 26.369  -7.469  137.373 1.00 41.21  ? 45  TRP C CD2 1 
ATOM   5741  N NE1 . TRP C 1 26  ? 26.636  -9.299  136.131 1.00 41.98  ? 45  TRP C NE1 1 
ATOM   5742  C CE2 . TRP C 1 26  ? 27.241  -8.131  136.492 1.00 41.52  ? 45  TRP C CE2 1 
ATOM   5743  C CE3 . TRP C 1 26  ? 26.754  -6.229  137.903 1.00 41.12  ? 45  TRP C CE3 1 
ATOM   5744  C CZ2 . TRP C 1 26  ? 28.483  -7.604  136.132 1.00 41.55  ? 45  TRP C CZ2 1 
ATOM   5745  C CZ3 . TRP C 1 26  ? 27.987  -5.705  137.548 1.00 41.07  ? 45  TRP C CZ3 1 
ATOM   5746  C CH2 . TRP C 1 26  ? 28.839  -6.385  136.681 1.00 41.43  ? 45  TRP C CH2 1 
ATOM   5747  N N   . ASP C 1 27  ? 22.168  -7.841  141.308 1.00 43.90  ? 46  ASP C N   1 
ATOM   5748  C CA  . ASP C 1 27  ? 20.897  -7.269  141.752 1.00 44.95  ? 46  ASP C CA  1 
ATOM   5749  C C   . ASP C 1 27  ? 21.042  -5.792  142.107 1.00 45.04  ? 46  ASP C C   1 
ATOM   5750  O O   . ASP C 1 27  ? 20.227  -4.950  141.706 1.00 45.89  ? 46  ASP C O   1 
ATOM   5751  C CB  . ASP C 1 27  ? 20.350  -8.034  142.952 1.00 45.31  ? 46  ASP C CB  1 
ATOM   5752  C CG  . ASP C 1 27  ? 18.941  -7.575  143.312 1.00 47.23  ? 46  ASP C CG  1 
ATOM   5753  O OD1 . ASP C 1 27  ? 18.808  -6.653  144.159 1.00 47.41  ? 46  ASP C OD1 1 
ATOM   5754  O OD2 . ASP C 1 27  ? 17.967  -8.129  142.720 1.00 49.66  ? 46  ASP C OD2 1 
ATOM   5755  N N   . THR C 1 28  ? 22.058  -5.468  142.898 1.00 41.72  ? 47  THR C N   1 
ATOM   5756  C CA  . THR C 1 28  ? 22.417  -4.115  143.232 1.00 41.46  ? 47  THR C CA  1 
ATOM   5757  C C   . THR C 1 28  ? 23.917  -4.003  143.020 1.00 40.40  ? 47  THR C C   1 
ATOM   5758  O O   . THR C 1 28  ? 24.564  -4.954  142.565 1.00 40.03  ? 47  THR C O   1 
ATOM   5759  C CB  . THR C 1 28  ? 22.017  -3.777  144.658 1.00 41.59  ? 47  THR C CB  1 
ATOM   5760  O OG1 . THR C 1 28  ? 22.616  -4.699  145.570 1.00 41.13  ? 47  THR C OG1 1 
ATOM   5761  C CG2 . THR C 1 28  ? 20.530  -3.796  144.808 1.00 43.16  ? 47  THR C CG2 1 
ATOM   5762  N N   . VAL C 1 29  ? 24.460  -2.828  143.326 1.00 38.39  ? 48  VAL C N   1 
ATOM   5763  C CA  . VAL C 1 29  ? 25.916  -2.633  143.252 1.00 37.54  ? 48  VAL C CA  1 
ATOM   5764  C C   . VAL C 1 29  ? 26.596  -3.632  144.156 1.00 36.88  ? 48  VAL C C   1 
ATOM   5765  O O   . VAL C 1 29  ? 26.245  -3.720  145.363 1.00 36.83  ? 48  VAL C O   1 
ATOM   5766  C CB  . VAL C 1 29  ? 26.282  -1.198  143.662 1.00 37.34  ? 48  VAL C CB  1 
ATOM   5767  C CG1 . VAL C 1 29  ? 27.807  -1.107  143.765 1.00 36.56  ? 48  VAL C CG1 1 
ATOM   5768  C CG2 . VAL C 1 29  ? 25.688  -0.218  142.680 1.00 38.00  ? 48  VAL C CG2 1 
ATOM   5769  N N   . PRO C 1 30  ? 27.596  -4.356  143.659 1.00 38.05  ? 49  PRO C N   1 
ATOM   5770  C CA  . PRO C 1 30  ? 28.308  -5.358  144.455 1.00 37.54  ? 49  PRO C CA  1 
ATOM   5771  C C   . PRO C 1 30  ? 29.369  -4.713  145.336 1.00 37.39  ? 49  PRO C C   1 
ATOM   5772  O O   . PRO C 1 30  ? 30.300  -4.067  144.856 1.00 37.34  ? 49  PRO C O   1 
ATOM   5773  C CB  . PRO C 1 30  ? 28.934  -6.288  143.402 1.00 37.86  ? 49  PRO C CB  1 
ATOM   5774  C CG  . PRO C 1 30  ? 28.915  -5.545  142.168 1.00 38.87  ? 49  PRO C CG  1 
ATOM   5775  C CD  . PRO C 1 30  ? 27.857  -4.497  142.222 1.00 38.64  ? 49  PRO C CD  1 
ATOM   5776  N N   . ILE C 1 31  ? 29.253  -4.968  146.625 1.00 36.87  ? 50  ILE C N   1 
ATOM   5777  C CA  . ILE C 1 31  ? 30.023  -4.288  147.637 1.00 36.97  ? 50  ILE C CA  1 
ATOM   5778  C C   . ILE C 1 31  ? 30.890  -5.294  148.358 1.00 36.21  ? 50  ILE C C   1 
ATOM   5779  O O   . ILE C 1 31  ? 30.455  -6.395  148.686 1.00 36.55  ? 50  ILE C O   1 
ATOM   5780  C CB  . ILE C 1 31  ? 29.087  -3.545  148.613 1.00 38.10  ? 50  ILE C CB  1 
ATOM   5781  C CG1 . ILE C 1 31  ? 28.290  -2.510  147.834 1.00 38.95  ? 50  ILE C CG1 1 
ATOM   5782  C CG2 . ILE C 1 31  ? 29.860  -2.893  149.717 1.00 38.26  ? 50  ILE C CG2 1 
ATOM   5783  C CD1 . ILE C 1 31  ? 29.136  -1.533  147.170 1.00 38.72  ? 50  ILE C CD1 1 
ATOM   5784  N N   . ALA C 1 32  ? 32.119  -4.911  148.608 1.00 37.57  ? 51  ALA C N   1 
ATOM   5785  C CA  . ALA C 1 32  ? 32.968  -5.619  149.538 1.00 37.44  ? 51  ALA C CA  1 
ATOM   5786  C C   . ALA C 1 32  ? 33.372  -4.639  150.622 1.00 37.27  ? 51  ALA C C   1 
ATOM   5787  O O   . ALA C 1 32  ? 33.219  -3.433  150.467 1.00 37.49  ? 51  ALA C O   1 
ATOM   5788  C CB  . ALA C 1 32  ? 34.191  -6.200  148.828 1.00 37.29  ? 51  ALA C CB  1 
ATOM   5789  N N   . PHE C 1 33  ? 33.874  -5.175  151.727 1.00 38.42  ? 52  PHE C N   1 
ATOM   5790  C CA  . PHE C 1 33  ? 34.387  -4.390  152.837 1.00 38.34  ? 52  PHE C CA  1 
ATOM   5791  C C   . PHE C 1 33  ? 35.826  -4.793  153.094 1.00 38.32  ? 52  PHE C C   1 
ATOM   5792  O O   . PHE C 1 33  ? 36.218  -5.948  152.879 1.00 38.34  ? 52  PHE C O   1 
ATOM   5793  C CB  . PHE C 1 33  ? 33.592  -4.604  154.121 1.00 39.14  ? 52  PHE C CB  1 
ATOM   5794  C CG  . PHE C 1 33  ? 32.158  -4.148  154.043 1.00 39.66  ? 52  PHE C CG  1 
ATOM   5795  C CD1 . PHE C 1 33  ? 31.144  -5.027  153.705 1.00 39.95  ? 52  PHE C CD1 1 
ATOM   5796  C CD2 . PHE C 1 33  ? 31.814  -2.853  154.328 1.00 40.01  ? 52  PHE C CD2 1 
ATOM   5797  C CE1 . PHE C 1 33  ? 29.807  -4.594  153.652 1.00 40.97  ? 52  PHE C CE1 1 
ATOM   5798  C CE2 . PHE C 1 33  ? 30.510  -2.436  154.254 1.00 40.89  ? 52  PHE C CE2 1 
ATOM   5799  C CZ  . PHE C 1 33  ? 29.514  -3.290  153.928 1.00 41.51  ? 52  PHE C CZ  1 
ATOM   5800  N N   . HIS C 1 34  ? 36.591  -3.851  153.602 1.00 39.46  ? 53  HIS C N   1 
ATOM   5801  C CA  . HIS C 1 34  ? 38.012  -4.035  153.901 1.00 39.62  ? 53  HIS C CA  1 
ATOM   5802  C C   . HIS C 1 34  ? 38.365  -3.039  155.008 1.00 39.90  ? 53  HIS C C   1 
ATOM   5803  O O   . HIS C 1 34  ? 38.714  -1.897  154.741 1.00 40.26  ? 53  HIS C O   1 
ATOM   5804  C CB  . HIS C 1 34  ? 38.867  -3.823  152.669 1.00 39.68  ? 53  HIS C CB  1 
ATOM   5805  C CG  . HIS C 1 34  ? 40.308  -4.172  152.860 1.00 40.19  ? 53  HIS C CG  1 
ATOM   5806  N ND1 . HIS C 1 34  ? 40.943  -5.133  152.105 1.00 41.04  ? 53  HIS C ND1 1 
ATOM   5807  C CD2 . HIS C 1 34  ? 41.233  -3.701  153.728 1.00 40.84  ? 53  HIS C CD2 1 
ATOM   5808  C CE1 . HIS C 1 34  ? 42.208  -5.214  152.479 1.00 41.29  ? 53  HIS C CE1 1 
ATOM   5809  N NE2 . HIS C 1 34  ? 42.407  -4.360  153.466 1.00 41.17  ? 53  HIS C NE2 1 
ATOM   5810  N N   . PHE C 1 35  ? 38.238  -3.478  156.242 1.00 40.98  ? 54  PHE C N   1 
ATOM   5811  C CA  . PHE C 1 35  ? 38.507  -2.578  157.343 1.00 41.45  ? 54  PHE C CA  1 
ATOM   5812  C C   . PHE C 1 35  ? 38.808  -3.377  158.600 1.00 41.71  ? 54  PHE C C   1 
ATOM   5813  O O   . PHE C 1 35  ? 38.599  -4.597  158.671 1.00 41.67  ? 54  PHE C O   1 
ATOM   5814  C CB  . PHE C 1 35  ? 37.319  -1.620  157.568 1.00 41.41  ? 54  PHE C CB  1 
ATOM   5815  C CG  . PHE C 1 35  ? 36.092  -2.304  158.066 1.00 41.62  ? 54  PHE C CG  1 
ATOM   5816  C CD1 . PHE C 1 35  ? 35.912  -2.539  159.424 1.00 43.03  ? 54  PHE C CD1 1 
ATOM   5817  C CD2 . PHE C 1 35  ? 35.134  -2.741  157.195 1.00 41.42  ? 54  PHE C CD2 1 
ATOM   5818  C CE1 . PHE C 1 35  ? 34.791  -3.206  159.887 1.00 43.76  ? 54  PHE C CE1 1 
ATOM   5819  C CE2 . PHE C 1 35  ? 33.998  -3.401  157.658 1.00 42.07  ? 54  PHE C CE2 1 
ATOM   5820  C CZ  . PHE C 1 35  ? 33.829  -3.638  158.995 1.00 43.32  ? 54  PHE C CZ  1 
ATOM   5821  N N   . GLY C 1 36  ? 39.320  -2.656  159.589 1.00 40.47  ? 55  GLY C N   1 
ATOM   5822  C CA  . GLY C 1 36  ? 39.538  -3.208  160.913 1.00 40.94  ? 55  GLY C CA  1 
ATOM   5823  C C   . GLY C 1 36  ? 39.106  -2.206  161.970 1.00 41.44  ? 55  GLY C C   1 
ATOM   5824  O O   . GLY C 1 36  ? 39.239  -0.989  161.803 1.00 41.79  ? 55  GLY C O   1 
ATOM   5825  N N   . LYS C 1 37  ? 38.598  -2.754  163.076 1.00 41.44  ? 56  LYS C N   1 
ATOM   5826  C CA  . LYS C 1 37  ? 38.098  -2.064  164.253 1.00 42.00  ? 56  LYS C CA  1 
ATOM   5827  C C   . LYS C 1 37  ? 38.959  -2.482  165.446 1.00 42.50  ? 56  LYS C C   1 
ATOM   5828  O O   . LYS C 1 37  ? 38.649  -3.414  166.166 1.00 43.03  ? 56  LYS C O   1 
ATOM   5829  C CB  . LYS C 1 37  ? 36.624  -2.406  164.458 1.00 42.62  ? 56  LYS C CB  1 
ATOM   5830  C CG  . LYS C 1 37  ? 36.023  -1.795  165.710 1.00 43.44  ? 56  LYS C CG  1 
ATOM   5831  C CD  . LYS C 1 37  ? 34.647  -2.369  166.003 1.00 44.53  ? 56  LYS C CD  1 
ATOM   5832  C CE  . LYS C 1 37  ? 33.997  -1.719  167.218 1.00 45.38  ? 56  LYS C CE  1 
ATOM   5833  N NZ  . LYS C 1 37  ? 32.602  -2.243  167.441 1.00 46.78  ? 56  LYS C NZ  1 
ATOM   5834  N N   A SER C 1 38  ? 40.035  -1.747  165.676 0.45 43.99  ? 57  SER C N   1 
ATOM   5835  N N   B SER C 1 38  ? 40.033  -1.741  165.673 0.55 43.79  ? 57  SER C N   1 
ATOM   5836  C CA  A SER C 1 38  ? 40.979  -2.099  166.730 0.45 44.96  ? 57  SER C CA  1 
ATOM   5837  C CA  B SER C 1 38  ? 40.986  -2.073  166.726 0.55 44.49  ? 57  SER C CA  1 
ATOM   5838  C C   A SER C 1 38  ? 40.324  -2.258  168.102 0.45 45.46  ? 57  SER C C   1 
ATOM   5839  C C   B SER C 1 38  ? 40.339  -2.239  168.102 0.55 45.24  ? 57  SER C C   1 
ATOM   5840  O O   A SER C 1 38  ? 40.670  -3.173  168.858 0.45 45.93  ? 57  SER C O   1 
ATOM   5841  O O   B SER C 1 38  ? 40.705  -3.146  168.861 0.55 45.71  ? 57  SER C O   1 
ATOM   5842  C CB  A SER C 1 38  ? 42.061  -1.020  166.802 0.45 45.66  ? 57  SER C CB  1 
ATOM   5843  C CB  B SER C 1 38  ? 42.060  -0.977  166.789 0.55 44.67  ? 57  SER C CB  1 
ATOM   5844  O OG  A SER C 1 38  ? 41.470  0.202   167.196 0.45 46.42  ? 57  SER C OG  1 
ATOM   5845  O OG  B SER C 1 38  ? 42.879  -0.983  165.635 0.55 44.32  ? 57  SER C OG  1 
ATOM   5846  N N   . GLN C 1 39  ? 39.378  -1.380  168.446 1.00 45.64  ? 58  GLN C N   1 
ATOM   5847  C CA  . GLN C 1 39  ? 38.908  -1.319  169.825 1.00 46.97  ? 58  GLN C CA  1 
ATOM   5848  C C   . GLN C 1 39  ? 38.130  -2.550  170.285 1.00 47.04  ? 58  GLN C C   1 
ATOM   5849  O O   . GLN C 1 39  ? 38.039  -2.785  171.500 1.00 48.18  ? 58  GLN C O   1 
ATOM   5850  C CB  . GLN C 1 39  ? 38.082  -0.043  170.009 1.00 48.29  ? 58  GLN C CB  1 
ATOM   5851  C CG  . GLN C 1 39  ? 36.928  0.104   169.056 1.00 49.23  ? 58  GLN C CG  1 
ATOM   5852  C CD  . GLN C 1 39  ? 37.222  1.097   167.927 1.00 48.78  ? 58  GLN C CD  1 
ATOM   5853  O OE1 . GLN C 1 39  ? 38.376  1.236   167.483 1.00 47.58  ? 58  GLN C OE1 1 
ATOM   5854  N NE2 . GLN C 1 39  ? 36.168  1.763   167.431 1.00 49.30  ? 58  GLN C NE2 1 
ATOM   5855  N N   . GLY C 1 40  ? 37.629  -3.374  169.369 1.00 45.96  ? 59  GLY C N   1 
ATOM   5856  C CA  . GLY C 1 40  ? 36.867  -4.548  169.762 1.00 46.31  ? 59  GLY C CA  1 
ATOM   5857  C C   . GLY C 1 40  ? 36.142  -5.147  168.578 1.00 45.49  ? 59  GLY C C   1 
ATOM   5858  O O   . GLY C 1 40  ? 36.263  -4.672  167.439 1.00 45.12  ? 59  GLY C O   1 
ATOM   5859  N N   . LEU C 1 41  ? 35.387  -6.215  168.849 1.00 44.53  ? 60  LEU C N   1 
ATOM   5860  C CA  . LEU C 1 41  ? 34.634  -6.816  167.758 1.00 44.29  ? 60  LEU C CA  1 
ATOM   5861  C C   . LEU C 1 41  ? 33.545  -5.866  167.250 1.00 44.80  ? 60  LEU C C   1 
ATOM   5862  O O   . LEU C 1 41  ? 33.130  -4.907  167.922 1.00 45.85  ? 60  LEU C O   1 
ATOM   5863  C CB  . LEU C 1 41  ? 33.963  -8.112  168.181 1.00 45.02  ? 60  LEU C CB  1 
ATOM   5864  C CG  . LEU C 1 41  ? 34.829  -9.337  168.444 1.00 44.91  ? 60  LEU C CG  1 
ATOM   5865  C CD1 . LEU C 1 41  ? 33.979  -10.441 168.980 1.00 45.99  ? 60  LEU C CD1 1 
ATOM   5866  C CD2 . LEU C 1 41  ? 35.530  -9.733  167.187 1.00 43.86  ? 60  LEU C CD2 1 
ATOM   5867  N N   . LEU C 1 42  ? 33.061  -6.164  166.051 1.00 43.86  ? 61  LEU C N   1 
ATOM   5868  C CA  . LEU C 1 42  ? 31.845  -5.519  165.594 1.00 44.50  ? 61  LEU C CA  1 
ATOM   5869  C C   . LEU C 1 42  ? 30.748  -5.757  166.619 1.00 46.16  ? 61  LEU C C   1 
ATOM   5870  O O   . LEU C 1 42  ? 30.685  -6.807  167.253 1.00 46.59  ? 61  LEU C O   1 
ATOM   5871  C CB  . LEU C 1 42  ? 31.416  -6.051  164.243 1.00 43.86  ? 61  LEU C CB  1 
ATOM   5872  C CG  . LEU C 1 42  ? 32.334  -5.892  163.039 1.00 42.82  ? 61  LEU C CG  1 
ATOM   5873  C CD1 . LEU C 1 42  ? 31.664  -6.546  161.769 1.00 42.57  ? 61  LEU C CD1 1 
ATOM   5874  C CD2 . LEU C 1 42  ? 32.675  -4.453  162.793 1.00 43.05  ? 61  LEU C CD2 1 
ATOM   5875  N N   . THR C 1 43  ? 29.897  -4.766  166.800 1.00 45.40  ? 62  THR C N   1 
ATOM   5876  C CA  . THR C 1 43  ? 28.662  -4.891  167.551 1.00 47.06  ? 62  THR C CA  1 
ATOM   5877  C C   . THR C 1 43  ? 27.626  -5.640  166.717 1.00 47.67  ? 62  THR C C   1 
ATOM   5878  O O   . THR C 1 43  ? 27.774  -5.829  165.509 1.00 46.67  ? 62  THR C O   1 
ATOM   5879  C CB  . THR C 1 43  ? 28.141  -3.510  167.930 1.00 48.45  ? 62  THR C CB  1 
ATOM   5880  O OG1 . THR C 1 43  ? 27.784  -2.790  166.732 1.00 48.10  ? 62  THR C OG1 1 
ATOM   5881  C CG2 . THR C 1 43  ? 29.218  -2.715  168.658 1.00 48.12  ? 62  THR C CG2 1 
ATOM   5882  N N   . LYS C 1 44  ? 26.561  -6.082  167.378 1.00 45.68  ? 63  LYS C N   1 
ATOM   5883  C CA  . LYS C 1 44  ? 25.499  -6.778  166.663 1.00 47.37  ? 63  LYS C CA  1 
ATOM   5884  C C   . LYS C 1 44  ? 24.937  -5.890  165.557 1.00 46.94  ? 63  LYS C C   1 
ATOM   5885  O O   . LYS C 1 44  ? 24.718  -6.350  164.432 1.00 46.27  ? 63  LYS C O   1 
ATOM   5886  C CB  . LYS C 1 44  ? 24.419  -7.226  167.649 1.00 51.19  ? 63  LYS C CB  1 
ATOM   5887  N N   . GLU C 1 45  ? 24.763  -4.596  165.829 1.00 48.52  ? 64  GLU C N   1 
ATOM   5888  C CA  . GLU C 1 45  ? 24.228  -3.702  164.810 1.00 48.77  ? 64  GLU C CA  1 
ATOM   5889  C C   . GLU C 1 45  ? 25.190  -3.587  163.630 1.00 45.80  ? 64  GLU C C   1 
ATOM   5890  O O   . GLU C 1 45  ? 24.794  -3.730  162.462 1.00 45.53  ? 64  GLU C O   1 
ATOM   5891  C CB  . GLU C 1 45  ? 23.936  -2.338  165.418 1.00 50.27  ? 64  GLU C CB  1 
ATOM   5892  N N   . GLU C 1 46  ? 26.469  -3.329  163.918 1.00 47.82  ? 65  GLU C N   1 
ATOM   5893  C CA  . GLU C 1 46  ? 27.486  -3.275  162.863 1.00 45.90  ? 65  GLU C CA  1 
ATOM   5894  C C   . GLU C 1 46  ? 27.585  -4.599  162.087 1.00 45.47  ? 65  GLU C C   1 
ATOM   5895  O O   . GLU C 1 46  ? 27.782  -4.608  160.862 1.00 44.34  ? 65  GLU C O   1 
ATOM   5896  C CB  . GLU C 1 46  ? 28.834  -2.895  163.484 1.00 44.90  ? 65  GLU C CB  1 
ATOM   5897  C CG  . GLU C 1 46  ? 28.876  -1.464  164.101 1.00 45.53  ? 65  GLU C CG  1 
ATOM   5898  C CD  . GLU C 1 46  ? 29.931  -1.284  165.202 1.00 45.56  ? 65  GLU C CD  1 
ATOM   5899  O OE1 . GLU C 1 46  ? 30.535  -2.284  165.599 1.00 45.12  ? 65  GLU C OE1 1 
ATOM   5900  O OE2 . GLU C 1 46  ? 30.185  -0.110  165.651 1.00 45.98  ? 65  GLU C OE2 1 
ATOM   5901  N N   . ALA C 1 47  ? 27.453  -5.735  162.776 1.00 44.34  ? 66  ALA C N   1 
ATOM   5902  C CA  . ALA C 1 47  ? 27.640  -7.005  162.070 1.00 43.47  ? 66  ALA C CA  1 
ATOM   5903  C C   . ALA C 1 47  ? 26.470  -7.313  161.126 1.00 44.04  ? 66  ALA C C   1 
ATOM   5904  O O   . ALA C 1 47  ? 26.677  -7.760  159.984 1.00 42.95  ? 66  ALA C O   1 
ATOM   5905  C CB  . ALA C 1 47  ? 27.844  -8.132  163.078 1.00 44.03  ? 66  ALA C CB  1 
ATOM   5906  N N   . GLU C 1 48  ? 25.240  -7.081  161.590 1.00 42.73  ? 67  GLU C N   1 
ATOM   5907  C CA  . GLU C 1 48  ? 24.082  -7.250  160.731 1.00 43.60  ? 67  GLU C CA  1 
ATOM   5908  C C   . GLU C 1 48  ? 24.172  -6.340  159.500 1.00 42.78  ? 67  GLU C C   1 
ATOM   5909  O O   . GLU C 1 48  ? 23.809  -6.762  158.393 1.00 42.61  ? 67  GLU C O   1 
ATOM   5910  C CB  . GLU C 1 48  ? 22.812  -6.983  161.543 1.00 45.94  ? 67  GLU C CB  1 
ATOM   5911  N N   . PHE C 1 49  ? 24.685  -5.102  159.668 1.00 45.47  ? 68  PHE C N   1 
ATOM   5912  C CA  . PHE C 1 49  ? 24.845  -4.161  158.548 1.00 44.29  ? 68  PHE C CA  1 
ATOM   5913  C C   . PHE C 1 49  ? 25.815  -4.694  157.502 1.00 42.60  ? 68  PHE C C   1 
ATOM   5914  O O   . PHE C 1 49  ? 25.530  -4.696  156.305 1.00 42.65  ? 68  PHE C O   1 
ATOM   5915  C CB  . PHE C 1 49  ? 25.361  -2.820  159.078 1.00 44.35  ? 68  PHE C CB  1 
ATOM   5916  C CG  . PHE C 1 49  ? 25.741  -1.809  157.994 1.00 43.29  ? 68  PHE C CG  1 
ATOM   5917  C CD1 . PHE C 1 49  ? 26.999  -1.803  157.419 1.00 41.60  ? 68  PHE C CD1 1 
ATOM   5918  C CD2 . PHE C 1 49  ? 24.847  -0.830  157.603 1.00 44.29  ? 68  PHE C CD2 1 
ATOM   5919  C CE1 . PHE C 1 49  ? 27.343  -0.855  156.443 1.00 41.10  ? 68  PHE C CE1 1 
ATOM   5920  C CE2 . PHE C 1 49  ? 25.188  0.129   156.633 1.00 43.71  ? 68  PHE C CE2 1 
ATOM   5921  C CZ  . PHE C 1 49  ? 26.430  0.111   156.046 1.00 41.58  ? 68  PHE C CZ  1 
ATOM   5922  N N   . VAL C 1 50  ? 26.997  -5.102  157.956 1.00 44.03  ? 69  VAL C N   1 
ATOM   5923  C CA  . VAL C 1 50  ? 27.990  -5.755  157.106 1.00 42.94  ? 69  VAL C CA  1 
ATOM   5924  C C   . VAL C 1 50  ? 27.430  -7.046  156.510 1.00 42.87  ? 69  VAL C C   1 
ATOM   5925  O O   . VAL C 1 50  ? 27.584  -7.322  155.314 1.00 42.19  ? 69  VAL C O   1 
ATOM   5926  C CB  . VAL C 1 50  ? 29.261  -6.031  157.939 1.00 43.33  ? 69  VAL C CB  1 
ATOM   5927  C CG1 . VAL C 1 50  ? 30.174  -7.028  157.254 1.00 43.23  ? 69  VAL C CG1 1 
ATOM   5928  C CG2 . VAL C 1 50  ? 30.010  -4.727  158.260 1.00 43.11  ? 69  VAL C CG2 1 
ATOM   5929  N N   . ALA C 1 51  ? 26.812  -7.881  157.342 1.00 42.81  ? 70  ALA C N   1 
ATOM   5930  C CA  . ALA C 1 51  ? 26.542  -9.236  156.871 1.00 42.54  ? 70  ALA C CA  1 
ATOM   5931  C C   . ALA C 1 51  ? 25.429  -9.239  155.828 1.00 43.14  ? 70  ALA C C   1 
ATOM   5932  O O   . ALA C 1 51  ? 25.421  -10.107 154.945 1.00 42.78  ? 70  ALA C O   1 
ATOM   5933  C CB  . ALA C 1 51  ? 26.222  -10.168 158.047 1.00 43.86  ? 70  ALA C CB  1 
ATOM   5934  N N   . THR C 1 52  ? 24.521  -8.251  155.877 1.00 41.81  ? 71  THR C N   1 
ATOM   5935  C CA  . THR C 1 52  ? 23.377  -8.244  154.981 1.00 42.91  ? 71  THR C CA  1 
ATOM   5936  C C   . THR C 1 52  ? 23.664  -7.587  153.639 1.00 41.93  ? 71  THR C C   1 
ATOM   5937  O O   . THR C 1 52  ? 22.853  -7.741  152.721 1.00 43.23  ? 71  THR C O   1 
ATOM   5938  C CB  . THR C 1 52  ? 22.201  -7.499  155.598 1.00 45.47  ? 71  THR C CB  1 
ATOM   5939  O OG1 . THR C 1 52  ? 22.597  -6.130  155.816 1.00 45.81  ? 71  THR C OG1 1 
ATOM   5940  C CG2 . THR C 1 52  ? 21.768  -8.136  156.868 1.00 47.48  ? 71  THR C CG2 1 
ATOM   5941  N N   . ARG C 1 53  ? 24.772  -6.867  153.526 1.00 41.26  ? 72  ARG C N   1 
ATOM   5942  C CA  . ARG C 1 53  ? 25.096  -6.041  152.378 1.00 40.61  ? 72  ARG C CA  1 
ATOM   5943  C C   . ARG C 1 53  ? 26.271  -6.574  151.597 1.00 39.16  ? 72  ARG C C   1 
ATOM   5944  O O   . ARG C 1 53  ? 26.622  -6.005  150.560 1.00 38.92  ? 72  ARG C O   1 
ATOM   5945  C CB  . ARG C 1 53  ? 25.398  -4.591  152.816 1.00 40.83  ? 72  ARG C CB  1 
ATOM   5946  C CG  . ARG C 1 53  ? 24.156  -4.010  153.421 1.00 42.61  ? 72  ARG C CG  1 
ATOM   5947  C CD  . ARG C 1 53  ? 24.131  -2.584  153.896 1.00 43.26  ? 72  ARG C CD  1 
ATOM   5948  N NE  . ARG C 1 53  ? 23.461  -2.669  155.187 1.00 44.74  ? 72  ARG C NE  1 
ATOM   5949  C CZ  . ARG C 1 53  ? 22.460  -1.913  155.601 1.00 46.41  ? 72  ARG C CZ  1 
ATOM   5950  N NH1 . ARG C 1 53  ? 21.968  -0.963  154.856 1.00 47.05  ? 72  ARG C NH1 1 
ATOM   5951  N NH2 . ARG C 1 53  ? 21.960  -2.113  156.815 1.00 48.14  ? 72  ARG C NH2 1 
ATOM   5952  N N   . SER C 1 54  ? 26.922  -7.619  152.083 1.00 39.04  ? 73  SER C N   1 
ATOM   5953  C CA  . SER C 1 54  ? 28.076  -8.117  151.361 1.00 38.04  ? 73  SER C CA  1 
ATOM   5954  C C   . SER C 1 54  ? 28.311  -9.564  151.721 1.00 37.89  ? 73  SER C C   1 
ATOM   5955  O O   . SER C 1 54  ? 27.964  -10.012 152.815 1.00 38.73  ? 73  SER C O   1 
ATOM   5956  C CB  . SER C 1 54  ? 29.332  -7.310  151.652 1.00 37.50  ? 73  SER C CB  1 
ATOM   5957  O OG  . SER C 1 54  ? 30.426  -7.745  150.866 1.00 36.97  ? 73  SER C OG  1 
ATOM   5958  N N   . ASN C 1 55  ? 28.866  -10.287 150.752 1.00 40.31  ? 74  ASN C N   1 
ATOM   5959  C CA  . ASN C 1 55  ? 29.381  -11.633 150.940 1.00 39.81  ? 74  ASN C CA  1 
ATOM   5960  C C   . ASN C 1 55  ? 30.902  -11.655 150.955 1.00 39.23  ? 74  ASN C C   1 
ATOM   5961  O O   . ASN C 1 55  ? 31.475  -12.739 150.799 1.00 39.24  ? 74  ASN C O   1 
ATOM   5962  C CB  . ASN C 1 55  ? 28.898  -12.580 149.836 1.00 39.86  ? 74  ASN C CB  1 
ATOM   5963  C CG  . ASN C 1 55  ? 27.416  -12.724 149.800 1.00 40.88  ? 74  ASN C CG  1 
ATOM   5964  O OD1 . ASN C 1 55  ? 26.721  -12.415 150.769 1.00 42.22  ? 74  ASN C OD1 1 
ATOM   5965  N ND2 . ASN C 1 55  ? 26.905  -13.232 148.673 1.00 41.72  ? 74  ASN C ND2 1 
ATOM   5966  N N   . PHE C 1 56  ? 31.565  -10.482 151.096 1.00 37.15  ? 75  PHE C N   1 
ATOM   5967  C CA  . PHE C 1 56  ? 32.995  -10.354 150.809 1.00 36.39  ? 75  PHE C CA  1 
ATOM   5968  C C   . PHE C 1 56  ? 33.636  -9.269  151.666 1.00 36.51  ? 75  PHE C C   1 
ATOM   5969  O O   . PHE C 1 56  ? 33.519  -8.076  151.389 1.00 36.91  ? 75  PHE C O   1 
ATOM   5970  C CB  . PHE C 1 56  ? 33.201  -10.064 149.323 1.00 36.73  ? 75  PHE C CB  1 
ATOM   5971  C CG  . PHE C 1 56  ? 34.589  -10.355 148.829 1.00 36.59  ? 75  PHE C CG  1 
ATOM   5972  C CD1 . PHE C 1 56  ? 35.446  -11.189 149.531 1.00 36.69  ? 75  PHE C CD1 1 
ATOM   5973  C CD2 . PHE C 1 56  ? 35.039  -9.797  147.638 1.00 36.92  ? 75  PHE C CD2 1 
ATOM   5974  C CE1 . PHE C 1 56  ? 36.724  -11.459 149.064 1.00 36.97  ? 75  PHE C CE1 1 
ATOM   5975  C CE2 . PHE C 1 56  ? 36.333  -10.053 147.169 1.00 37.20  ? 75  PHE C CE2 1 
ATOM   5976  C CZ  . PHE C 1 56  ? 37.173  -10.898 147.898 1.00 37.27  ? 75  PHE C CZ  1 
ATOM   5977  N N   . ILE C 1 57  ? 34.240  -9.680  152.785 1.00 38.28  ? 76  ILE C N   1 
ATOM   5978  C CA  . ILE C 1 57  ? 34.881  -8.721  153.733 1.00 38.25  ? 76  ILE C CA  1 
ATOM   5979  C C   . ILE C 1 57  ? 36.326  -9.168  153.972 1.00 38.24  ? 76  ILE C C   1 
ATOM   5980  O O   . ILE C 1 57  ? 36.563  -10.380 153.883 1.00 38.53  ? 76  ILE C O   1 
ATOM   5981  C CB  . ILE C 1 57  ? 34.100  -8.627  155.057 1.00 38.77  ? 76  ILE C CB  1 
ATOM   5982  C CG1 . ILE C 1 57  ? 34.726  -7.593  155.992 1.00 39.11  ? 76  ILE C CG1 1 
ATOM   5983  C CG2 . ILE C 1 57  ? 33.974  -9.994  155.733 1.00 39.06  ? 76  ILE C CG2 1 
ATOM   5984  C CD1 . ILE C 1 57  ? 33.775  -7.042  157.037 1.00 40.02  ? 76  ILE C CD1 1 
ATOM   5985  N N   . CYS C 1 58  ? 37.246  -8.234  154.220 1.00 41.89  ? 77  CYS C N   1 
ATOM   5986  C CA  . CYS C 1 58  ? 38.654  -8.554  154.566 1.00 41.87  ? 77  CYS C CA  1 
ATOM   5987  C C   . CYS C 1 58  ? 39.000  -7.835  155.874 1.00 42.45  ? 77  CYS C C   1 
ATOM   5988  O O   . CYS C 1 58  ? 39.048  -6.590  155.865 1.00 42.40  ? 77  CYS C O   1 
ATOM   5989  C CB  . CYS C 1 58  ? 39.632  -8.127  153.483 1.00 41.87  ? 77  CYS C CB  1 
ATOM   5990  S SG  . CYS C 1 58  ? 41.353  -8.176  154.047 1.00 42.45  ? 77  CYS C SG  1 
ATOM   5991  N N   . LEU C 1 59  ? 39.228  -8.592  156.948 1.00 39.88  ? 78  LEU C N   1 
ATOM   5992  C CA  . LEU C 1 59  ? 39.501  -7.968  158.267 1.00 40.10  ? 78  LEU C CA  1 
ATOM   5993  C C   . LEU C 1 59  ? 40.959  -7.492  158.308 1.00 40.19  ? 78  LEU C C   1 
ATOM   5994  O O   . LEU C 1 59  ? 41.837  -8.319  158.011 1.00 40.62  ? 78  LEU C O   1 
ATOM   5995  C CB  . LEU C 1 59  ? 39.153  -8.962  159.371 1.00 40.52  ? 78  LEU C CB  1 
ATOM   5996  C CG  . LEU C 1 59  ? 37.663  -9.295  159.506 1.00 40.72  ? 78  LEU C CG  1 
ATOM   5997  C CD1 . LEU C 1 59  ? 37.438  -10.449 160.456 1.00 40.93  ? 78  LEU C CD1 1 
ATOM   5998  C CD2 . LEU C 1 59  ? 36.859  -8.087  159.952 1.00 41.20  ? 78  LEU C CD2 1 
ATOM   5999  N N   . GLU C 1 60  ? 41.205  -6.235  158.688 1.00 41.34  ? 79  GLU C N   1 
ATOM   6000  C CA  . GLU C 1 60  ? 42.515  -5.625  158.709 1.00 41.55  ? 79  GLU C CA  1 
ATOM   6001  C C   . GLU C 1 60  ? 43.300  -5.898  159.998 1.00 42.26  ? 79  GLU C C   1 
ATOM   6002  O O   . GLU C 1 60  ? 42.750  -6.268  161.034 1.00 42.68  ? 79  GLU C O   1 
ATOM   6003  C CB  . GLU C 1 60  ? 42.345  -4.114  158.523 1.00 41.80  ? 79  GLU C CB  1 
ATOM   6004  C CG  . GLU C 1 60  ? 42.479  -3.643  157.095 1.00 42.36  ? 79  GLU C CG  1 
ATOM   6005  C CD  . GLU C 1 60  ? 43.930  -3.531  156.675 1.00 43.25  ? 79  GLU C CD  1 
ATOM   6006  O OE1 . GLU C 1 60  ? 44.839  -3.563  157.551 1.00 43.73  ? 79  GLU C OE1 1 
ATOM   6007  O OE2 . GLU C 1 60  ? 44.144  -3.419  155.452 1.00 43.93  ? 79  GLU C OE2 1 
ATOM   6008  N N   . LYS C 1 61  ? 44.615  -5.670  159.908 1.00 45.12  ? 80  LYS C N   1 
ATOM   6009  C CA  . LYS C 1 61  ? 45.525  -5.619  161.047 1.00 45.86  ? 80  LYS C CA  1 
ATOM   6010  C C   . LYS C 1 61  ? 44.949  -4.807  162.206 1.00 46.18  ? 80  LYS C C   1 
ATOM   6011  O O   . LYS C 1 61  ? 44.477  -3.679  162.021 1.00 46.10  ? 80  LYS C O   1 
ATOM   6012  C CB  . LYS C 1 61  ? 46.873  -4.997  160.609 1.00 47.09  ? 80  LYS C CB  1 
ATOM   6013  C CG  . LYS C 1 61  ? 46.752  -3.505  160.220 1.00 47.74  ? 80  LYS C CG  1 
ATOM   6014  C CD  . LYS C 1 61  ? 48.105  -2.828  159.895 1.00 48.66  ? 80  LYS C CD  1 
ATOM   6015  C CE  . LYS C 1 61  ? 48.466  -2.903  158.400 1.00 49.31  ? 80  LYS C CE  1 
ATOM   6016  N NZ  . LYS C 1 61  ? 47.284  -2.835  157.415 1.00 49.17  ? 80  LYS C NZ  1 
ATOM   6017  N N   . GLY C 1 62  ? 45.038  -5.359  163.397 1.00 44.32  ? 81  GLY C N   1 
ATOM   6018  C CA  . GLY C 1 62  ? 44.597  -4.670  164.582 1.00 44.57  ? 81  GLY C CA  1 
ATOM   6019  C C   . GLY C 1 62  ? 43.215  -5.049  165.051 1.00 44.36  ? 81  GLY C C   1 
ATOM   6020  O O   . GLY C 1 62  ? 42.823  -4.656  166.151 1.00 45.14  ? 81  GLY C O   1 
ATOM   6021  N N   . HIS C 1 63  ? 42.496  -5.843  164.285 1.00 43.59  ? 82  HIS C N   1 
ATOM   6022  C CA  . HIS C 1 63  ? 41.063  -5.924  164.497 1.00 43.32  ? 82  HIS C CA  1 
ATOM   6023  C C   . HIS C 1 63  ? 40.741  -6.564  165.840 1.00 43.97  ? 82  HIS C C   1 
ATOM   6024  O O   . HIS C 1 63  ? 41.131  -7.715  166.114 1.00 44.32  ? 82  HIS C O   1 
ATOM   6025  C CB  . HIS C 1 63  ? 40.377  -6.686  163.376 1.00 42.82  ? 82  HIS C CB  1 
ATOM   6026  C CG  . HIS C 1 63  ? 38.898  -6.743  163.545 1.00 42.83  ? 82  HIS C CG  1 
ATOM   6027  N ND1 . HIS C 1 63  ? 38.097  -5.631  163.402 1.00 43.17  ? 82  HIS C ND1 1 
ATOM   6028  C CD2 . HIS C 1 63  ? 38.080  -7.760  163.890 1.00 43.04  ? 82  HIS C CD2 1 
ATOM   6029  C CE1 . HIS C 1 63  ? 36.844  -5.966  163.634 1.00 43.65  ? 82  HIS C CE1 1 
ATOM   6030  N NE2 . HIS C 1 63  ? 36.809  -7.254  163.938 1.00 43.42  ? 82  HIS C NE2 1 
ATOM   6031  N N   . ALA C 1 64  ? 39.966  -5.837  166.643 1.00 44.80  ? 83  ALA C N   1 
ATOM   6032  C CA  . ALA C 1 64  ? 39.469  -6.275  167.934 1.00 45.37  ? 83  ALA C CA  1 
ATOM   6033  C C   . ALA C 1 64  ? 40.595  -6.587  168.890 1.00 46.22  ? 83  ALA C C   1 
ATOM   6034  O O   . ALA C 1 64  ? 40.381  -7.317  169.865 1.00 47.22  ? 83  ALA C O   1 
ATOM   6035  C CB  . ALA C 1 64  ? 38.544  -7.498  167.797 1.00 45.73  ? 83  ALA C CB  1 
ATOM   6036  N N   . THR C 1 65  ? 41.788  -6.030  168.658 1.00 45.64  ? 84  THR C N   1 
ATOM   6037  C CA  . THR C 1 65  ? 42.941  -6.365  169.498 1.00 46.18  ? 84  THR C CA  1 
ATOM   6038  C C   . THR C 1 65  ? 42.824  -5.821  170.914 1.00 47.30  ? 84  THR C C   1 
ATOM   6039  O O   . THR C 1 65  ? 43.377  -6.422  171.843 1.00 48.28  ? 84  THR C O   1 
ATOM   6040  C CB  . THR C 1 65  ? 44.226  -5.843  168.868 1.00 46.38  ? 84  THR C CB  1 
ATOM   6041  O OG1 . THR C 1 65  ? 44.045  -4.479  168.456 1.00 46.15  ? 84  THR C OG1 1 
ATOM   6042  C CG2 . THR C 1 65  ? 44.588  -6.702  167.661 1.00 45.87  ? 84  THR C CG2 1 
ATOM   6043  N N   . ARG C 1 66  ? 42.099  -4.718  171.120 1.00 49.03  ? 85  ARG C N   1 
ATOM   6044  C CA  . ARG C 1 66  ? 41.972  -4.201  172.487 1.00 50.13  ? 85  ARG C CA  1 
ATOM   6045  C C   . ARG C 1 66  ? 41.339  -5.230  173.423 1.00 50.82  ? 85  ARG C C   1 
ATOM   6046  O O   . ARG C 1 66  ? 41.653  -5.259  174.614 1.00 52.32  ? 85  ARG C O   1 
ATOM   6047  C CB  . ARG C 1 66  ? 41.170  -2.894  172.493 1.00 50.54  ? 85  ARG C CB  1 
ATOM   6048  C CG  . ARG C 1 66  ? 40.665  -2.463  173.848 1.00 52.15  ? 85  ARG C CG  1 
ATOM   6049  C CD  . ARG C 1 66  ? 40.188  -1.031  173.825 1.00 52.56  ? 85  ARG C CD  1 
ATOM   6050  N NE  . ARG C 1 66  ? 41.233  -0.159  173.299 1.00 53.15  ? 85  ARG C NE  1 
ATOM   6051  C CZ  . ARG C 1 66  ? 41.041  1.084   172.894 1.00 53.79  ? 85  ARG C CZ  1 
ATOM   6052  N NH1 . ARG C 1 66  ? 39.836  1.634   172.928 1.00 54.20  ? 85  ARG C NH1 1 
ATOM   6053  N NH2 . ARG C 1 66  ? 42.089  1.803   172.478 1.00 53.90  ? 85  ARG C NH2 1 
ATOM   6054  N N   . THR C 1 67  ? 40.469  -6.088  172.889 1.00 48.79  ? 86  THR C N   1 
ATOM   6055  C CA  . THR C 1 67  ? 39.720  -7.073  173.650 1.00 49.49  ? 86  THR C CA  1 
ATOM   6056  C C   . THR C 1 67  ? 40.167  -8.501  173.385 1.00 49.58  ? 86  THR C C   1 
ATOM   6057  O O   . THR C 1 67  ? 39.771  -9.412  174.124 1.00 50.77  ? 86  THR C O   1 
ATOM   6058  C CB  . THR C 1 67  ? 38.231  -6.974  173.306 1.00 49.74  ? 86  THR C CB  1 
ATOM   6059  O OG1 . THR C 1 67  ? 38.065  -7.154  171.890 1.00 48.88  ? 86  THR C OG1 1 
ATOM   6060  C CG2 . THR C 1 67  ? 37.675  -5.629  173.705 1.00 50.44  ? 86  THR C CG2 1 
ATOM   6061  N N   . HIS C 1 68  ? 40.933  -8.732  172.328 1.00 47.98  ? 87  HIS C N   1 
ATOM   6062  C CA  . HIS C 1 68  ? 41.350  -10.066 171.950 1.00 47.87  ? 87  HIS C CA  1 
ATOM   6063  C C   . HIS C 1 68  ? 42.851  -10.213 171.811 1.00 48.27  ? 87  HIS C C   1 
ATOM   6064  O O   . HIS C 1 68  ? 43.315  -11.286 171.423 1.00 48.43  ? 87  HIS C O   1 
ATOM   6065  C CB  . HIS C 1 68  ? 40.700  -10.463 170.633 1.00 47.01  ? 87  HIS C CB  1 
ATOM   6066  C CG  . HIS C 1 68  ? 39.261  -10.796 170.780 1.00 47.15  ? 87  HIS C CG  1 
ATOM   6067  N ND1 . HIS C 1 68  ? 38.306  -9.833  171.024 1.00 47.71  ? 87  HIS C ND1 1 
ATOM   6068  C CD2 . HIS C 1 68  ? 38.610  -11.985 170.744 1.00 47.58  ? 87  HIS C CD2 1 
ATOM   6069  C CE1 . HIS C 1 68  ? 37.121  -10.413 171.107 1.00 48.15  ? 87  HIS C CE1 1 
ATOM   6070  N NE2 . HIS C 1 68  ? 37.280  -11.721 170.952 1.00 48.17  ? 87  HIS C NE2 1 
ATOM   6071  N N   . GLY C 1 69  ? 43.612  -9.168  172.084 1.00 47.12  ? 88  GLY C N   1 
ATOM   6072  C CA  . GLY C 1 69  ? 45.044  -9.265  172.203 1.00 47.60  ? 88  GLY C CA  1 
ATOM   6073  C C   . GLY C 1 69  ? 45.773  -9.221  170.886 1.00 47.36  ? 88  GLY C C   1 
ATOM   6074  O O   . GLY C 1 69  ? 46.646  -8.360  170.662 1.00 48.62  ? 88  GLY C O   1 
ATOM   6075  N N   . THR C 1 70  ? 45.414  -10.147 170.014 1.00 45.90  ? 89  THR C N   1 
ATOM   6076  C CA  . THR C 1 70  ? 46.095  -10.337 168.753 1.00 45.16  ? 89  THR C CA  1 
ATOM   6077  C C   . THR C 1 70  ? 45.119  -10.194 167.583 1.00 44.04  ? 89  THR C C   1 
ATOM   6078  O O   . THR C 1 70  ? 43.908  -10.411 167.695 1.00 43.82  ? 89  THR C O   1 
ATOM   6079  C CB  . THR C 1 70  ? 46.731  -11.733 168.703 1.00 46.22  ? 89  THR C CB  1 
ATOM   6080  O OG1 . THR C 1 70  ? 45.651  -12.672 168.708 1.00 45.95  ? 89  THR C OG1 1 
ATOM   6081  C CG2 . THR C 1 70  ? 47.642  -11.977 169.877 1.00 47.57  ? 89  THR C CG2 1 
ATOM   6082  N N   . THR C 1 71  ? 45.666  -9.857  166.423 1.00 44.86  ? 90  THR C N   1 
ATOM   6083  C CA  . THR C 1 71  ? 44.819  -9.760  165.239 1.00 43.99  ? 90  THR C CA  1 
ATOM   6084  C C   . THR C 1 71  ? 44.195  -11.115 164.875 1.00 43.98  ? 90  THR C C   1 
ATOM   6085  O O   . THR C 1 71  ? 43.049  -11.166 164.406 1.00 43.55  ? 90  THR C O   1 
ATOM   6086  C CB  . THR C 1 71  ? 45.651  -9.176  164.100 1.00 43.89  ? 90  THR C CB  1 
ATOM   6087  O OG1 . THR C 1 71  ? 46.109  -7.853  164.472 1.00 44.09  ? 90  THR C OG1 1 
ATOM   6088  C CG2 . THR C 1 71  ? 44.852  -9.113  162.843 1.00 43.27  ? 90  THR C CG2 1 
ATOM   6089  N N   . GLU C 1 72  ? 44.914  -12.219 165.142 1.00 44.01  ? 91  GLU C N   1 
ATOM   6090  C CA  . GLU C 1 72  ? 44.434  -13.559 164.817 1.00 43.80  ? 91  GLU C CA  1 
ATOM   6091  C C   . GLU C 1 72  ? 43.231  -13.942 165.677 1.00 43.92  ? 91  GLU C C   1 
ATOM   6092  O O   . GLU C 1 72  ? 42.224  -14.455 165.165 1.00 43.57  ? 91  GLU C O   1 
ATOM   6093  C CB  . GLU C 1 72  ? 45.575  -14.569 164.984 1.00 44.85  ? 91  GLU C CB  1 
ATOM   6094  C CG  . GLU C 1 72  ? 46.812  -14.312 164.108 1.00 45.45  ? 91  GLU C CG  1 
ATOM   6095  C CD  . GLU C 1 72  ? 48.014  -13.756 164.884 1.00 45.73  ? 91  GLU C CD  1 
ATOM   6096  O OE1 . GLU C 1 72  ? 47.811  -12.925 165.804 1.00 46.09  ? 91  GLU C OE1 1 
ATOM   6097  O OE2 . GLU C 1 72  ? 49.174  -14.111 164.579 1.00 46.22  ? 91  GLU C OE2 1 
ATOM   6098  N N   . ALA C 1 73  ? 43.295  -13.675 166.976 1.00 43.69  ? 92  ALA C N   1 
ATOM   6099  C CA  . ALA C 1 73  ? 42.111  -13.886 167.797 1.00 43.83  ? 92  ALA C CA  1 
ATOM   6100  C C   . ALA C 1 73  ? 40.982  -12.943 167.393 1.00 43.20  ? 92  ALA C C   1 
ATOM   6101  O O   . ALA C 1 73  ? 39.821  -13.365 167.277 1.00 43.31  ? 92  ALA C O   1 
ATOM   6102  C CB  . ALA C 1 73  ? 42.451  -13.687 169.268 1.00 45.03  ? 92  ALA C CB  1 
ATOM   6103  N N   . GLY C 1 74  ? 41.296  -11.671 167.156 1.00 42.62  ? 93  GLY C N   1 
ATOM   6104  C CA  . GLY C 1 74  ? 40.244  -10.742 166.807 1.00 42.48  ? 93  GLY C CA  1 
ATOM   6105  C C   . GLY C 1 74  ? 39.526  -11.148 165.544 1.00 41.61  ? 93  GLY C C   1 
ATOM   6106  O O   . GLY C 1 74  ? 38.292  -11.217 165.502 1.00 41.83  ? 93  GLY C O   1 
ATOM   6107  N N   . ILE C 1 75  ? 40.292  -11.471 164.508 1.00 42.27  ? 94  ILE C N   1 
ATOM   6108  C CA  . ILE C 1 75  ? 39.678  -11.824 163.230 1.00 41.67  ? 94  ILE C CA  1 
ATOM   6109  C C   . ILE C 1 75  ? 38.899  -13.119 163.344 1.00 41.83  ? 94  ILE C C   1 
ATOM   6110  O O   . ILE C 1 75  ? 37.805  -13.239 162.787 1.00 41.73  ? 94  ILE C O   1 
ATOM   6111  C CB  . ILE C 1 75  ? 40.739  -11.911 162.107 1.00 41.17  ? 94  ILE C CB  1 
ATOM   6112  C CG1 . ILE C 1 75  ? 41.233  -10.486 161.796 1.00 41.15  ? 94  ILE C CG1 1 
ATOM   6113  C CG2 . ILE C 1 75  ? 40.177  -12.689 160.910 1.00 40.96  ? 94  ILE C CG2 1 
ATOM   6114  C CD1 . ILE C 1 75  ? 42.319  -10.437 160.761 1.00 41.15  ? 94  ILE C CD1 1 
ATOM   6115  N N   . GLU C 1 76  ? 39.456  -14.114 164.046 1.00 41.85  ? 95  GLU C N   1 
ATOM   6116  C CA  . GLU C 1 76  ? 38.832  -15.438 164.079 1.00 42.03  ? 95  GLU C CA  1 
ATOM   6117  C C   . GLU C 1 76  ? 37.467  -15.353 164.731 1.00 42.27  ? 95  GLU C C   1 
ATOM   6118  O O   . GLU C 1 76  ? 36.492  -15.936 164.256 1.00 42.45  ? 95  GLU C O   1 
ATOM   6119  C CB  . GLU C 1 76  ? 39.740  -16.416 164.835 1.00 42.94  ? 95  GLU C CB  1 
ATOM   6120  C CG  . GLU C 1 76  ? 39.117  -17.776 165.141 1.00 42.84  ? 95  GLU C CG  1 
ATOM   6121  C CD  . GLU C 1 76  ? 38.790  -18.635 163.869 1.00 42.71  ? 95  GLU C CD  1 
ATOM   6122  O OE1 . GLU C 1 76  ? 39.393  -18.419 162.772 1.00 42.51  ? 95  GLU C OE1 1 
ATOM   6123  O OE2 . GLU C 1 76  ? 37.915  -19.527 163.999 1.00 43.18  ? 95  GLU C OE2 1 
ATOM   6124  N N   . ALA C 1 77  ? 37.391  -14.603 165.824 1.00 43.37  ? 96  ALA C N   1 
ATOM   6125  C CA  . ALA C 1 77  ? 36.124  -14.366 166.498 1.00 44.08  ? 96  ALA C CA  1 
ATOM   6126  C C   . ALA C 1 77  ? 35.173  -13.582 165.613 1.00 44.10  ? 96  ALA C C   1 
ATOM   6127  O O   . ALA C 1 77  ? 33.955  -13.783 165.657 1.00 44.57  ? 96  ALA C O   1 
ATOM   6128  C CB  . ALA C 1 77  ? 36.384  -13.596 167.787 1.00 45.24  ? 96  ALA C CB  1 
ATOM   6129  N N   . GLU C 1 78  ? 35.710  -12.658 164.834 1.00 44.36  ? 97  GLU C N   1 
ATOM   6130  C CA  . GLU C 1 78  ? 34.842  -11.850 163.999 1.00 44.25  ? 97  GLU C CA  1 
ATOM   6131  C C   . GLU C 1 78  ? 34.261  -12.672 162.854 1.00 43.62  ? 97  GLU C C   1 
ATOM   6132  O O   . GLU C 1 78  ? 33.074  -12.535 162.528 1.00 44.30  ? 97  GLU C O   1 
ATOM   6133  C CB  . GLU C 1 78  ? 35.612  -10.641 163.470 1.00 43.91  ? 97  GLU C CB  1 
ATOM   6134  C CG  . GLU C 1 78  ? 34.722  -9.669  162.794 1.00 43.87  ? 97  GLU C CG  1 
ATOM   6135  C CD  . GLU C 1 78  ? 33.763  -9.054  163.788 1.00 45.16  ? 97  GLU C CD  1 
ATOM   6136  O OE1 . GLU C 1 78  ? 34.238  -8.292  164.662 1.00 45.36  ? 97  GLU C OE1 1 
ATOM   6137  O OE2 . GLU C 1 78  ? 32.532  -9.328  163.691 1.00 46.23  ? 97  GLU C OE2 1 
ATOM   6138  N N   . ALA C 1 79  ? 35.100  -13.500 162.227 1.00 41.76  ? 98  ALA C N   1 
ATOM   6139  C CA  . ALA C 1 79  ? 34.646  -14.416 161.190 1.00 41.33  ? 98  ALA C CA  1 
ATOM   6140  C C   . ALA C 1 79  ? 33.482  -15.244 161.685 1.00 41.74  ? 98  ALA C C   1 
ATOM   6141  O O   . ALA C 1 79  ? 32.556  -15.565 160.931 1.00 42.17  ? 98  ALA C O   1 
ATOM   6142  C CB  . ALA C 1 79  ? 35.784  -15.343 160.758 1.00 41.27  ? 98  ALA C CB  1 
ATOM   6143  N N   . ARG C 1 80  ? 33.525  -15.612 162.956 1.00 41.92  ? 99  ARG C N   1 
ATOM   6144  C CA  . ARG C 1 80  ? 32.509  -16.488 163.501 1.00 43.06  ? 99  ARG C CA  1 
ATOM   6145  C C   . ARG C 1 80  ? 31.182  -15.762 163.620 1.00 43.92  ? 99  ARG C C   1 
ATOM   6146  O O   . ARG C 1 80  ? 30.134  -16.318 163.276 1.00 44.60  ? 99  ARG C O   1 
ATOM   6147  C CB  . ARG C 1 80  ? 32.978  -17.043 164.840 1.00 44.19  ? 99  ARG C CB  1 
ATOM   6148  C CG  . ARG C 1 80  ? 33.984  -18.191 164.716 1.00 44.44  ? 99  ARG C CG  1 
ATOM   6149  C CD  . ARG C 1 80  ? 34.563  -18.439 166.081 1.00 45.79  ? 99  ARG C CD  1 
ATOM   6150  N NE  . ARG C 1 80  ? 35.711  -19.342 166.133 1.00 46.75  ? 99  ARG C NE  1 
ATOM   6151  C CZ  . ARG C 1 80  ? 36.005  -20.106 167.188 1.00 49.14  ? 99  ARG C CZ  1 
ATOM   6152  N NH1 . ARG C 1 80  ? 35.195  -20.173 168.241 1.00 50.91  ? 99  ARG C NH1 1 
ATOM   6153  N NH2 . ARG C 1 80  ? 37.137  -20.808 167.187 1.00 49.77  ? 99  ARG C NH2 1 
ATOM   6154  N N   . GLN C 1 81  ? 31.195  -14.512 164.063 1.00 43.28  ? 100 GLN C N   1 
ATOM   6155  C CA  . GLN C 1 81  ? 29.915  -13.826 164.248 1.00 44.55  ? 100 GLN C CA  1 
ATOM   6156  C C   . GLN C 1 81  ? 29.349  -13.357 162.919 1.00 44.15  ? 100 GLN C C   1 
ATOM   6157  O O   . GLN C 1 81  ? 28.126  -13.274 162.777 1.00 45.28  ? 100 GLN C O   1 
ATOM   6158  C CB  . GLN C 1 81  ? 30.048  -12.661 165.239 1.00 46.27  ? 100 GLN C CB  1 
ATOM   6159  C CG  . GLN C 1 81  ? 30.142  -11.252 164.657 1.00 46.24  ? 100 GLN C CG  1 
ATOM   6160  C CD  . GLN C 1 81  ? 29.976  -10.117 165.730 1.00 47.44  ? 100 GLN C CD  1 
ATOM   6161  O OE1 . GLN C 1 81  ? 29.010  -10.096 166.504 1.00 49.36  ? 100 GLN C OE1 1 
ATOM   6162  N NE2 . GLN C 1 81  ? 30.958  -9.212  165.783 1.00 46.41  ? 100 GLN C NE2 1 
ATOM   6163  N N   . LEU C 1 82  ? 30.211  -13.059 161.937 1.00 43.19  ? 101 LEU C N   1 
ATOM   6164  C CA  . LEU C 1 82  ? 29.680  -12.656 160.650 1.00 42.86  ? 101 LEU C CA  1 
ATOM   6165  C C   . LEU C 1 82  ? 29.076  -13.839 159.944 1.00 42.72  ? 101 LEU C C   1 
ATOM   6166  O O   . LEU C 1 82  ? 27.978  -13.734 159.398 1.00 43.28  ? 101 LEU C O   1 
ATOM   6167  C CB  . LEU C 1 82  ? 30.758  -12.029 159.778 1.00 41.71  ? 101 LEU C CB  1 
ATOM   6168  C CG  . LEU C 1 82  ? 31.084  -10.583 160.160 1.00 41.88  ? 101 LEU C CG  1 
ATOM   6169  C CD1 . LEU C 1 82  ? 32.168  -10.041 159.275 1.00 41.22  ? 101 LEU C CD1 1 
ATOM   6170  C CD2 . LEU C 1 82  ? 29.905  -9.680  160.073 1.00 43.36  ? 101 LEU C CD2 1 
ATOM   6171  N N   . LYS C 1 83  ? 29.772  -14.984 159.960 1.00 43.62  ? 102 LYS C N   1 
ATOM   6172  C CA  . LYS C 1 83  ? 29.273  -16.152 159.249 1.00 43.77  ? 102 LYS C CA  1 
ATOM   6173  C C   . LYS C 1 83  ? 28.052  -16.714 159.931 1.00 45.07  ? 102 LYS C C   1 
ATOM   6174  O O   . LYS C 1 83  ? 27.230  -17.357 159.281 1.00 45.63  ? 102 LYS C O   1 
ATOM   6175  C CB  . LYS C 1 83  ? 30.339  -17.224 159.156 1.00 43.73  ? 102 LYS C CB  1 
ATOM   6176  C CG  . LYS C 1 83  ? 31.385  -16.935 158.131 1.00 43.33  ? 102 LYS C CG  1 
ATOM   6177  C CD  . LYS C 1 83  ? 32.141  -18.188 157.845 1.00 44.02  ? 102 LYS C CD  1 
ATOM   6178  C CE  . LYS C 1 83  ? 33.282  -18.004 156.848 1.00 43.35  ? 102 LYS C CE  1 
ATOM   6179  N NZ  . LYS C 1 83  ? 33.933  -19.393 156.640 1.00 42.56  ? 102 LYS C NZ  1 
ATOM   6180  N N   . ASN C 1 84  ? 27.932  -16.518 161.242 1.00 41.33  ? 103 ASN C N   1 
ATOM   6181  C CA  . ASN C 1 84  ? 26.680  -16.875 161.900 1.00 43.01  ? 103 ASN C CA  1 
ATOM   6182  C C   . ASN C 1 84  ? 25.518  -16.063 161.323 1.00 43.52  ? 103 ASN C C   1 
ATOM   6183  O O   . ASN C 1 84  ? 24.381  -16.545 161.262 1.00 44.82  ? 103 ASN C O   1 
ATOM   6184  C CB  . ASN C 1 84  ? 26.821  -16.675 163.412 1.00 44.91  ? 103 ASN C CB  1 
ATOM   6185  C CG  . ASN C 1 84  ? 25.509  -16.857 164.155 1.00 48.08  ? 103 ASN C CG  1 
ATOM   6186  O OD1 . ASN C 1 84  ? 24.991  -17.945 164.223 1.00 49.16  ? 103 ASN C OD1 1 
ATOM   6187  N ND2 . ASN C 1 84  ? 24.979  -15.779 164.725 1.00 49.81  ? 103 ASN C ND2 1 
ATOM   6188  N N   . LEU C 1 85  ? 25.784  -14.856 160.864 1.00 41.88  ? 104 LEU C N   1 
ATOM   6189  C CA  . LEU C 1 85  ? 24.732  -14.012 160.332 1.00 42.57  ? 104 LEU C CA  1 
ATOM   6190  C C   . LEU C 1 85  ? 24.519  -14.282 158.858 1.00 41.77  ? 104 LEU C C   1 
ATOM   6191  O O   . LEU C 1 85  ? 23.388  -14.261 158.378 1.00 43.24  ? 104 LEU C O   1 
ATOM   6192  C CB  . LEU C 1 85  ? 25.090  -12.532 160.526 1.00 42.75  ? 104 LEU C CB  1 
ATOM   6193  C CG  . LEU C 1 85  ? 25.164  -11.977 161.950 1.00 44.20  ? 104 LEU C CG  1 
ATOM   6194  C CD1 . LEU C 1 85  ? 25.924  -10.639 162.040 1.00 43.86  ? 104 LEU C CD1 1 
ATOM   6195  C CD2 . LEU C 1 85  ? 23.745  -11.815 162.470 1.00 46.52  ? 104 LEU C CD2 1 
ATOM   6196  N N   . ASN C 1 86  ? 25.607  -14.514 158.131 1.00 43.87  ? 105 ASN C N   1 
ATOM   6197  C CA  . ASN C 1 86  ? 25.556  -14.685 156.683 1.00 44.59  ? 105 ASN C CA  1 
ATOM   6198  C C   . ASN C 1 86  ? 26.453  -15.855 156.335 1.00 44.32  ? 105 ASN C C   1 
ATOM   6199  O O   . ASN C 1 86  ? 27.683  -15.695 156.238 1.00 42.42  ? 105 ASN C O   1 
ATOM   6200  C CB  . ASN C 1 86  ? 26.004  -13.441 155.920 1.00 42.88  ? 105 ASN C CB  1 
ATOM   6201  C CG  . ASN C 1 86  ? 26.130  -13.705 154.439 1.00 43.35  ? 105 ASN C CG  1 
ATOM   6202  O OD1 . ASN C 1 86  ? 25.743  -14.762 153.972 1.00 45.29  ? 105 ASN C OD1 1 
ATOM   6203  N ND2 . ASN C 1 86  ? 26.700  -12.790 153.706 1.00 41.31  ? 105 ASN C ND2 1 
ATOM   6204  N N   . PRO C 1 87  ? 25.881  -17.032 156.113 1.00 43.36  ? 106 PRO C N   1 
ATOM   6205  C CA  . PRO C 1 87  ? 26.713  -18.217 155.819 1.00 43.80  ? 106 PRO C CA  1 
ATOM   6206  C C   . PRO C 1 87  ? 27.490  -18.094 154.520 1.00 43.08  ? 106 PRO C C   1 
ATOM   6207  O O   . PRO C 1 87  ? 28.498  -18.795 154.337 1.00 43.09  ? 106 PRO C O   1 
ATOM   6208  C CB  . PRO C 1 87  ? 25.703  -19.364 155.748 1.00 47.43  ? 106 PRO C CB  1 
ATOM   6209  C CG  . PRO C 1 87  ? 24.372  -18.802 156.081 1.00 49.82  ? 106 PRO C CG  1 
ATOM   6210  C CD  . PRO C 1 87  ? 24.443  -17.315 156.182 1.00 46.70  ? 106 PRO C CD  1 
ATOM   6211  N N   . LYS C 1 88  ? 27.092  -17.173 153.627 1.00 45.79  ? 107 LYS C N   1 
ATOM   6212  C CA  . LYS C 1 88  ? 27.799  -16.995 152.354 1.00 44.68  ? 107 LYS C CA  1 
ATOM   6213  C C   . LYS C 1 88  ? 28.980  -16.033 152.436 1.00 41.98  ? 107 LYS C C   1 
ATOM   6214  O O   . LYS C 1 88  ? 29.739  -15.926 151.454 1.00 41.15  ? 107 LYS C O   1 
ATOM   6215  C CB  . LYS C 1 88  ? 26.809  -16.554 151.271 1.00 46.60  ? 107 LYS C CB  1 
ATOM   6216  C CG  . LYS C 1 88  ? 25.669  -17.564 151.134 1.00 50.63  ? 107 LYS C CG  1 
ATOM   6217  C CD  . LYS C 1 88  ? 25.064  -17.633 149.738 1.00 52.08  ? 107 LYS C CD  1 
ATOM   6218  C CE  . LYS C 1 88  ? 25.114  -19.107 149.290 1.00 54.90  ? 107 LYS C CE  1 
ATOM   6219  N NZ  . LYS C 1 88  ? 24.026  -19.533 148.360 1.00 56.66  ? 107 LYS C NZ  1 
ATOM   6220  N N   . MET C 1 89  ? 29.215  -15.423 153.602 1.00 45.51  ? 108 MET C N   1 
ATOM   6221  C CA  . MET C 1 89  ? 30.270  -14.439 153.700 1.00 43.20  ? 108 MET C CA  1 
ATOM   6222  C C   . MET C 1 89  ? 31.625  -15.071 153.571 1.00 42.15  ? 108 MET C C   1 
ATOM   6223  O O   . MET C 1 89  ? 31.896  -16.088 154.214 1.00 43.38  ? 108 MET C O   1 
ATOM   6224  C CB  . MET C 1 89  ? 30.234  -13.681 155.009 1.00 42.95  ? 108 MET C CB  1 
ATOM   6225  C CG  . MET C 1 89  ? 30.881  -12.318 154.766 1.00 41.87  ? 108 MET C CG  1 
ATOM   6226  S SD  . MET C 1 89  ? 29.948  -11.105 155.608 1.00 42.24  ? 108 MET C SD  1 
ATOM   6227  C CE  . MET C 1 89  ? 30.457  -9.565  154.809 1.00 40.81  ? 108 MET C CE  1 
ATOM   6228  N N   . LYS C 1 90  ? 32.480  -14.451 152.769 1.00 39.39  ? 109 LYS C N   1 
ATOM   6229  C CA  . LYS C 1 90  ? 33.894  -14.795 152.667 1.00 38.41  ? 109 LYS C CA  1 
ATOM   6230  C C   . LYS C 1 90  ? 34.678  -13.791 153.500 1.00 37.27  ? 109 LYS C C   1 
ATOM   6231  O O   . LYS C 1 90  ? 34.738  -12.584 153.173 1.00 36.74  ? 109 LYS C O   1 
ATOM   6232  C CB  . LYS C 1 90  ? 34.355  -14.803 151.217 1.00 38.57  ? 109 LYS C CB  1 
ATOM   6233  C CG  . LYS C 1 90  ? 33.597  -15.796 150.302 1.00 40.40  ? 109 LYS C CG  1 
ATOM   6234  C CD  . LYS C 1 90  ? 33.853  -17.236 150.666 1.00 41.76  ? 109 LYS C CD  1 
ATOM   6235  C CE  . LYS C 1 90  ? 33.281  -18.153 149.592 1.00 43.62  ? 109 LYS C CE  1 
ATOM   6236  N NZ  . LYS C 1 90  ? 33.651  -19.557 149.872 1.00 45.23  ? 109 LYS C NZ  1 
ATOM   6237  N N   . VAL C 1 91  ? 35.293  -14.291 154.581 1.00 38.78  ? 110 VAL C N   1 
ATOM   6238  C CA  . VAL C 1 91  ? 36.097  -13.453 155.456 1.00 37.90  ? 110 VAL C CA  1 
ATOM   6239  C C   . VAL C 1 91  ? 37.564  -13.704 155.169 1.00 37.74  ? 110 VAL C C   1 
ATOM   6240  O O   . VAL C 1 91  ? 38.030  -14.847 155.203 1.00 38.21  ? 110 VAL C O   1 
ATOM   6241  C CB  . VAL C 1 91  ? 35.756  -13.697 156.932 1.00 38.29  ? 110 VAL C CB  1 
ATOM   6242  C CG1 . VAL C 1 91  ? 36.510  -12.703 157.775 1.00 38.00  ? 110 VAL C CG1 1 
ATOM   6243  C CG2 . VAL C 1 91  ? 34.259  -13.565 157.155 1.00 39.25  ? 110 VAL C CG2 1 
ATOM   6244  N N   . ILE C 1 92  ? 38.294  -12.626 154.892 1.00 38.24  ? 111 ILE C N   1 
ATOM   6245  C CA  . ILE C 1 92  ? 39.651  -12.693 154.384 1.00 38.38  ? 111 ILE C CA  1 
ATOM   6246  C C   . ILE C 1 92  ? 40.592  -12.220 155.477 1.00 38.22  ? 111 ILE C C   1 
ATOM   6247  O O   . ILE C 1 92  ? 40.412  -11.130 156.041 1.00 38.34  ? 111 ILE C O   1 
ATOM   6248  C CB  . ILE C 1 92  ? 39.830  -11.857 153.104 1.00 38.37  ? 111 ILE C CB  1 
ATOM   6249  C CG1 . ILE C 1 92  ? 38.733  -12.187 152.096 1.00 38.75  ? 111 ILE C CG1 1 
ATOM   6250  C CG2 . ILE C 1 92  ? 41.230  -12.081 152.527 1.00 38.66  ? 111 ILE C CG2 1 
ATOM   6251  C CD1 . ILE C 1 92  ? 38.679  -13.636 151.608 1.00 39.99  ? 111 ILE C CD1 1 
ATOM   6252  N N   . PHE C 1 93  ? 41.629  -13.007 155.718 1.00 40.19  ? 112 PHE C N   1 
ATOM   6253  C CA  . PHE C 1 93  ? 42.595  -12.722 156.760 1.00 40.59  ? 112 PHE C CA  1 
ATOM   6254  C C   . PHE C 1 93  ? 43.709  -11.839 156.221 1.00 40.57  ? 112 PHE C C   1 
ATOM   6255  O O   . PHE C 1 93  ? 44.427  -12.244 155.298 1.00 41.09  ? 112 PHE C O   1 
ATOM   6256  C CB  . PHE C 1 93  ? 43.159  -14.029 157.282 1.00 41.04  ? 112 PHE C CB  1 
ATOM   6257  C CG  . PHE C 1 93  ? 44.199  -13.861 158.317 1.00 41.91  ? 112 PHE C CG  1 
ATOM   6258  C CD1 . PHE C 1 93  ? 43.857  -13.571 159.622 1.00 42.56  ? 112 PHE C CD1 1 
ATOM   6259  C CD2 . PHE C 1 93  ? 45.537  -14.031 158.002 1.00 43.03  ? 112 PHE C CD2 1 
ATOM   6260  C CE1 . PHE C 1 93  ? 44.839  -13.457 160.589 1.00 43.58  ? 112 PHE C CE1 1 
ATOM   6261  C CE2 . PHE C 1 93  ? 46.513  -13.920 158.965 1.00 44.37  ? 112 PHE C CE2 1 
ATOM   6262  C CZ  . PHE C 1 93  ? 46.158  -13.617 160.252 1.00 44.31  ? 112 PHE C CZ  1 
ATOM   6263  N N   . TYR C 1 94  ? 43.855  -10.643 156.804 1.00 41.14  ? 113 TYR C N   1 
ATOM   6264  C CA  . TYR C 1 94  ? 44.937  -9.740  156.427 1.00 41.48  ? 113 TYR C CA  1 
ATOM   6265  C C   . TYR C 1 94  ? 46.274  -10.267 156.947 1.00 42.71  ? 113 TYR C C   1 
ATOM   6266  O O   . TYR C 1 94  ? 46.423  -10.595 158.138 1.00 43.73  ? 113 TYR C O   1 
ATOM   6267  C CB  . TYR C 1 94  ? 44.693  -8.322  156.967 1.00 41.75  ? 113 TYR C CB  1 
ATOM   6268  C CG  . TYR C 1 94  ? 45.761  -7.348  156.513 1.00 42.04  ? 113 TYR C CG  1 
ATOM   6269  C CD1 . TYR C 1 94  ? 46.941  -7.222  157.225 1.00 43.12  ? 113 TYR C CD1 1 
ATOM   6270  C CD2 . TYR C 1 94  ? 45.607  -6.591  155.350 1.00 41.51  ? 113 TYR C CD2 1 
ATOM   6271  C CE1 . TYR C 1 94  ? 47.953  -6.374  156.816 1.00 43.54  ? 113 TYR C CE1 1 
ATOM   6272  C CE2 . TYR C 1 94  ? 46.610  -5.741  154.920 1.00 41.93  ? 113 TYR C CE2 1 
ATOM   6273  C CZ  . TYR C 1 94  ? 47.787  -5.633  155.668 1.00 42.82  ? 113 TYR C CZ  1 
ATOM   6274  O OH  . TYR C 1 94  ? 48.811  -4.788  155.286 1.00 43.77  ? 113 TYR C OH  1 
ATOM   6275  N N   . TRP C 1 95  ? 47.265  -10.317 156.059 1.00 39.91  ? 114 TRP C N   1 
ATOM   6276  C CA  . TRP C 1 95  ? 48.558  -10.893 156.414 1.00 41.13  ? 114 TRP C CA  1 
ATOM   6277  C C   . TRP C 1 95  ? 49.600  -10.328 155.459 1.00 41.87  ? 114 TRP C C   1 
ATOM   6278  O O   . TRP C 1 95  ? 49.633  -10.687 154.273 1.00 41.80  ? 114 TRP C O   1 
ATOM   6279  C CB  . TRP C 1 95  ? 48.484  -12.412 156.340 1.00 41.42  ? 114 TRP C CB  1 
ATOM   6280  C CG  . TRP C 1 95  ? 49.707  -13.134 156.770 1.00 42.72  ? 114 TRP C CG  1 
ATOM   6281  C CD1 . TRP C 1 95  ? 50.271  -14.180 156.143 1.00 43.07  ? 114 TRP C CD1 1 
ATOM   6282  C CD2 . TRP C 1 95  ? 50.513  -12.884 157.951 1.00 44.43  ? 114 TRP C CD2 1 
ATOM   6283  N NE1 . TRP C 1 95  ? 51.394  -14.600 156.830 1.00 44.75  ? 114 TRP C NE1 1 
ATOM   6284  C CE2 . TRP C 1 95  ? 51.559  -13.830 157.945 1.00 45.74  ? 114 TRP C CE2 1 
ATOM   6285  C CE3 . TRP C 1 95  ? 50.459  -11.943 158.993 1.00 45.22  ? 114 TRP C CE3 1 
ATOM   6286  C CZ2 . TRP C 1 95  ? 52.539  -13.870 158.928 1.00 47.86  ? 114 TRP C CZ2 1 
ATOM   6287  C CZ3 . TRP C 1 95  ? 51.423  -11.984 159.959 1.00 47.24  ? 114 TRP C CZ3 1 
ATOM   6288  C CH2 . TRP C 1 95  ? 52.449  -12.951 159.932 1.00 48.59  ? 114 TRP C CH2 1 
ATOM   6289  N N   . ASN C 1 96  ? 50.453  -9.467  155.970 1.00 42.27  ? 115 ASN C N   1 
ATOM   6290  C CA  . ASN C 1 96  ? 51.291  -8.681  155.086 1.00 42.90  ? 115 ASN C CA  1 
ATOM   6291  C C   . ASN C 1 96  ? 52.462  -9.504  154.560 1.00 44.33  ? 115 ASN C C   1 
ATOM   6292  O O   . ASN C 1 96  ? 53.251  -10.063 155.333 1.00 45.81  ? 115 ASN C O   1 
ATOM   6293  C CB  . ASN C 1 96  ? 51.797  -7.425  155.800 1.00 43.55  ? 115 ASN C CB  1 
ATOM   6294  C CG  . ASN C 1 96  ? 52.337  -6.406  154.829 1.00 44.25  ? 115 ASN C CG  1 
ATOM   6295  O OD1 . ASN C 1 96  ? 53.373  -6.610  154.205 1.00 45.86  ? 115 ASN C OD1 1 
ATOM   6296  N ND2 . ASN C 1 96  ? 51.643  -5.298  154.698 1.00 43.52  ? 115 ASN C ND2 1 
ATOM   6297  N N   . THR C 1 97  ? 52.604  -9.502  153.237 1.00 43.42  ? 116 THR C N   1 
ATOM   6298  C CA  . THR C 1 97  ? 53.666  -10.230 152.567 1.00 44.64  ? 116 THR C CA  1 
ATOM   6299  C C   . THR C 1 97  ? 55.053  -9.697  152.841 1.00 47.16  ? 116 THR C C   1 
ATOM   6300  O O   . THR C 1 97  ? 56.027  -10.404 152.597 1.00 48.97  ? 116 THR C O   1 
ATOM   6301  C CB  . THR C 1 97  ? 53.465  -10.171 151.060 1.00 44.22  ? 116 THR C CB  1 
ATOM   6302  O OG1 . THR C 1 97  ? 52.067  -10.272 150.783 1.00 42.55  ? 116 THR C OG1 1 
ATOM   6303  C CG2 . THR C 1 97  ? 54.222  -11.286 150.363 1.00 45.75  ? 116 THR C CG2 1 
ATOM   6304  N N   . PHE C 1 98  ? 55.172  -8.467  153.306 1.00 45.60  ? 117 PHE C N   1 
ATOM   6305  C CA  . PHE C 1 98  ? 56.450  -7.773  153.312 1.00 48.05  ? 117 PHE C CA  1 
ATOM   6306  C C   . PHE C 1 98  ? 56.828  -7.211  154.663 1.00 49.02  ? 117 PHE C C   1 
ATOM   6307  O O   . PHE C 1 98  ? 58.020  -6.938  154.884 1.00 51.75  ? 117 PHE C O   1 
ATOM   6308  C CB  . PHE C 1 98  ? 56.402  -6.629  152.294 1.00 48.36  ? 117 PHE C CB  1 
ATOM   6309  C CG  . PHE C 1 98  ? 57.745  -6.172  151.816 1.00 51.02  ? 117 PHE C CG  1 
ATOM   6310  C CD1 . PHE C 1 98  ? 58.837  -7.040  151.784 1.00 53.59  ? 117 PHE C CD1 1 
ATOM   6311  C CD2 . PHE C 1 98  ? 57.902  -4.868  151.356 1.00 51.87  ? 117 PHE C CD2 1 
ATOM   6312  C CE1 . PHE C 1 98  ? 60.066  -6.605  151.329 1.00 56.33  ? 117 PHE C CE1 1 
ATOM   6313  C CE2 . PHE C 1 98  ? 59.120  -4.420  150.890 1.00 54.60  ? 117 PHE C CE2 1 
ATOM   6314  C CZ  . PHE C 1 98  ? 60.211  -5.276  150.884 1.00 56.84  ? 117 PHE C CZ  1 
ATOM   6315  N N   . LEU C 1 99  ? 55.878  -7.053  155.582 1.00 49.64  ? 118 LEU C N   1 
ATOM   6316  C CA  . LEU C 1 99  ? 56.084  -6.218  156.757 1.00 49.86  ? 118 LEU C CA  1 
ATOM   6317  C C   . LEU C 1 99  ? 55.757  -6.963  158.044 1.00 49.73  ? 118 LEU C C   1 
ATOM   6318  O O   . LEU C 1 99  ? 54.723  -7.630  158.153 1.00 48.27  ? 118 LEU C O   1 
ATOM   6319  C CB  . LEU C 1 99  ? 55.243  -4.933  156.630 1.00 48.33  ? 118 LEU C CB  1 
ATOM   6320  C CG  . LEU C 1 99  ? 55.447  -4.094  155.356 1.00 48.97  ? 118 LEU C CG  1 
ATOM   6321  C CD1 . LEU C 1 99  ? 54.575  -2.859  155.487 1.00 47.86  ? 118 LEU C CD1 1 
ATOM   6322  C CD2 . LEU C 1 99  ? 56.877  -3.643  155.062 1.00 51.63  ? 118 LEU C CD2 1 
ATOM   6323  N N   . ASP C 1 100 ? 56.652  -6.818  159.027 1.00 52.74  ? 119 ASP C N   1 
ATOM   6324  C CA  . ASP C 1 100 ? 56.514  -7.477  160.333 1.00 52.68  ? 119 ASP C CA  1 
ATOM   6325  C C   . ASP C 1 100 ? 55.729  -6.556  161.268 1.00 51.08  ? 119 ASP C C   1 
ATOM   6326  O O   . ASP C 1 100 ? 56.276  -5.828  162.086 1.00 52.18  ? 119 ASP C O   1 
ATOM   6327  C CB  . ASP C 1 100 ? 57.890  -7.845  160.888 1.00 55.05  ? 119 ASP C CB  1 
ATOM   6328  C CG  . ASP C 1 100 ? 57.861  -8.228  162.372 1.00 55.02  ? 119 ASP C CG  1 
ATOM   6329  O OD1 . ASP C 1 100 ? 56.819  -8.712  162.851 1.00 53.66  ? 119 ASP C OD1 1 
ATOM   6330  O OD2 . ASP C 1 100 ? 58.885  -8.065  163.076 1.00 56.19  ? 119 ASP C OD2 1 
ATOM   6331  N N   . TYR C 1 101 ? 54.408  -6.580  161.110 1.00 50.44  ? 120 TYR C N   1 
ATOM   6332  C CA  . TYR C 1 101 ? 53.518  -5.820  161.968 1.00 49.20  ? 120 TYR C CA  1 
ATOM   6333  C C   . TYR C 1 101 ? 53.469  -6.486  163.321 1.00 49.46  ? 120 TYR C C   1 
ATOM   6334  O O   . TYR C 1 101 ? 53.598  -7.699  163.428 1.00 49.95  ? 120 TYR C O   1 
ATOM   6335  C CB  . TYR C 1 101 ? 52.110  -5.732  161.371 1.00 47.48  ? 120 TYR C CB  1 
ATOM   6336  C CG  . TYR C 1 101 ? 51.983  -4.688  160.292 1.00 46.83  ? 120 TYR C CG  1 
ATOM   6337  C CD1 . TYR C 1 101 ? 51.982  -3.328  160.608 1.00 46.61  ? 120 TYR C CD1 1 
ATOM   6338  C CD2 . TYR C 1 101 ? 51.889  -5.054  158.963 1.00 46.52  ? 120 TYR C CD2 1 
ATOM   6339  C CE1 . TYR C 1 101 ? 51.877  -2.350  159.611 1.00 46.43  ? 120 TYR C CE1 1 
ATOM   6340  C CE2 . TYR C 1 101 ? 51.792  -4.115  157.979 1.00 46.04  ? 120 TYR C CE2 1 
ATOM   6341  C CZ  . TYR C 1 101 ? 51.783  -2.759  158.306 1.00 46.06  ? 120 TYR C CZ  1 
ATOM   6342  O OH  . TYR C 1 101 ? 51.677  -1.834  157.314 1.00 46.43  ? 120 TYR C OH  1 
ATOM   6343  N N   . SER C 1 102 ? 53.279  -5.679  164.354 1.00 50.93  ? 121 SER C N   1 
ATOM   6344  C CA  . SER C 1 102 ? 53.420  -6.139  165.729 1.00 51.65  ? 121 SER C CA  1 
ATOM   6345  C C   . SER C 1 102 ? 52.102  -6.591  166.346 1.00 50.72  ? 121 SER C C   1 
ATOM   6346  O O   . SER C 1 102 ? 52.115  -7.244  167.405 1.00 51.79  ? 121 SER C O   1 
ATOM   6347  C CB  . SER C 1 102 ? 54.006  -5.017  166.599 1.00 52.46  ? 121 SER C CB  1 
ATOM   6348  O OG  . SER C 1 102 ? 53.063  -3.968  166.654 1.00 51.81  ? 121 SER C OG  1 
ATOM   6349  N N   . MET C 1 103 ? 50.975  -6.231  165.730 1.00 51.51  ? 122 MET C N   1 
ATOM   6350  C CA  . MET C 1 103 ? 49.671  -6.535  166.293 1.00 50.83  ? 122 MET C CA  1 
ATOM   6351  C C   . MET C 1 103 ? 49.245  -8.006  166.074 1.00 50.47  ? 122 MET C C   1 
ATOM   6352  O O   . MET C 1 103 ? 48.077  -8.344  166.325 1.00 49.83  ? 122 MET C O   1 
ATOM   6353  C CB  . MET C 1 103 ? 48.620  -5.581  165.701 1.00 50.59  ? 122 MET C CB  1 
ATOM   6354  C CG  . MET C 1 103 ? 48.605  -5.442  164.152 1.00 50.57  ? 122 MET C CG  1 
ATOM   6355  S SD  . MET C 1 103 ? 49.739  -4.177  163.514 1.00 50.63  ? 122 MET C SD  1 
ATOM   6356  C CE  . MET C 1 103 ? 49.191  -2.700  164.295 1.00 51.83  ? 122 MET C CE  1 
ATOM   6357  N N   . PHE C 1 104 ? 50.163  -8.871  165.633 1.00 47.47  ? 123 PHE C N   1 
ATOM   6358  C CA  . PHE C 1 104 ? 49.889  -10.282 165.393 1.00 47.21  ? 123 PHE C CA  1 
ATOM   6359  C C   . PHE C 1 104 ? 50.703  -11.145 166.348 1.00 47.86  ? 123 PHE C C   1 
ATOM   6360  O O   . PHE C 1 104 ? 51.901  -10.913 166.543 1.00 49.00  ? 123 PHE C O   1 
ATOM   6361  C CB  . PHE C 1 104 ? 50.254  -10.703 163.956 1.00 47.47  ? 123 PHE C CB  1 
ATOM   6362  C CG  . PHE C 1 104 ? 49.428  -10.051 162.880 1.00 46.51  ? 123 PHE C CG  1 
ATOM   6363  C CD1 . PHE C 1 104 ? 49.691  -8.751  162.484 1.00 46.47  ? 123 PHE C CD1 1 
ATOM   6364  C CD2 . PHE C 1 104 ? 48.395  -10.764 162.256 1.00 45.91  ? 123 PHE C CD2 1 
ATOM   6365  C CE1 . PHE C 1 104 ? 48.932  -8.171  161.487 1.00 45.65  ? 123 PHE C CE1 1 
ATOM   6366  C CE2 . PHE C 1 104 ? 47.623  -10.192 161.278 1.00 45.11  ? 123 PHE C CE2 1 
ATOM   6367  C CZ  . PHE C 1 104 ? 47.886  -8.901  160.869 1.00 44.91  ? 123 PHE C CZ  1 
ATOM   6368  N N   . ALA C 1 105 ? 50.059  -12.183 166.900 1.00 47.63  ? 124 ALA C N   1 
ATOM   6369  C CA  . ALA C 1 105 ? 50.768  -13.198 167.685 1.00 48.68  ? 124 ALA C CA  1 
ATOM   6370  C C   . ALA C 1 105 ? 51.988  -13.729 166.956 1.00 49.46  ? 124 ALA C C   1 
ATOM   6371  O O   . ALA C 1 105 ? 53.007  -14.040 167.573 1.00 50.76  ? 124 ALA C O   1 
ATOM   6372  C CB  . ALA C 1 105 ? 49.816  -14.352 167.993 1.00 48.08  ? 124 ALA C CB  1 
ATOM   6373  N N   . ALA C 1 106 ? 51.891  -13.878 165.648 1.00 47.47  ? 125 ALA C N   1 
ATOM   6374  C CA  . ALA C 1 106 ? 53.038  -14.296 164.866 1.00 48.35  ? 125 ALA C CA  1 
ATOM   6375  C C   . ALA C 1 106 ? 54.238  -13.367 165.016 1.00 49.63  ? 125 ALA C C   1 
ATOM   6376  O O   . ALA C 1 106 ? 55.370  -13.788 164.773 1.00 50.97  ? 125 ALA C O   1 
ATOM   6377  C CB  . ALA C 1 106 ? 52.658  -14.396 163.383 1.00 48.16  ? 125 ALA C CB  1 
ATOM   6378  N N   . HIS C 1 107 ? 54.051  -12.119 165.415 1.00 49.53  ? 126 HIS C N   1 
ATOM   6379  C CA  . HIS C 1 107 ? 55.214  -11.237 165.483 1.00 51.06  ? 126 HIS C CA  1 
ATOM   6380  C C   . HIS C 1 107 ? 56.253  -11.801 166.464 1.00 52.34  ? 126 HIS C C   1 
ATOM   6381  O O   . HIS C 1 107 ? 57.471  -11.750 166.227 1.00 53.86  ? 126 HIS C O   1 
ATOM   6382  C CB  . HIS C 1 107 ? 54.776  -9.827  165.877 1.00 50.31  ? 126 HIS C CB  1 
ATOM   6383  C CG  . HIS C 1 107 ? 55.911  -8.962  166.305 1.00 51.67  ? 126 HIS C CG  1 
ATOM   6384  N ND1 . HIS C 1 107 ? 56.860  -8.516  165.413 1.00 52.79  ? 126 HIS C ND1 1 
ATOM   6385  C CD2 . HIS C 1 107 ? 56.309  -8.545  167.528 1.00 52.42  ? 126 HIS C CD2 1 
ATOM   6386  C CE1 . HIS C 1 107 ? 57.774  -7.827  166.064 1.00 53.91  ? 126 HIS C CE1 1 
ATOM   6387  N NE2 . HIS C 1 107 ? 57.460  -7.827  167.347 1.00 53.61  ? 126 HIS C NE2 1 
ATOM   6388  N N   . LYS C 1 108 ? 55.795  -12.364 167.559 1.00 52.63  ? 127 LYS C N   1 
ATOM   6389  C CA  . LYS C 1 108 ? 56.751  -12.823 168.541 1.00 53.80  ? 127 LYS C CA  1 
ATOM   6390  C C   . LYS C 1 108 ? 57.402  -14.131 168.151 1.00 54.87  ? 127 LYS C C   1 
ATOM   6391  O O   . LYS C 1 108 ? 58.455  -14.454 168.683 1.00 56.46  ? 127 LYS C O   1 
ATOM   6392  C CB  . LYS C 1 108 ? 56.070  -12.814 169.896 1.00 54.00  ? 127 LYS C CB  1 
ATOM   6393  C CG  . LYS C 1 108 ? 55.038  -13.797 170.237 1.00 53.49  ? 127 LYS C CG  1 
ATOM   6394  C CD  . LYS C 1 108 ? 54.617  -13.440 171.711 1.00 54.64  ? 127 LYS C CD  1 
ATOM   6395  C CE  . LYS C 1 108 ? 53.925  -12.036 171.775 1.00 53.77  ? 127 LYS C CE  1 
ATOM   6396  N NZ  . LYS C 1 108 ? 53.544  -11.534 173.171 1.00 54.84  ? 127 LYS C NZ  1 
ATOM   6397  N N   . GLU C 1 109 ? 56.893  -14.812 167.140 1.00 55.04  ? 128 GLU C N   1 
ATOM   6398  C CA  . GLU C 1 109 ? 57.662  -15.861 166.493 1.00 55.85  ? 128 GLU C CA  1 
ATOM   6399  C C   . GLU C 1 109 ? 58.718  -15.279 165.568 1.00 57.33  ? 128 GLU C C   1 
ATOM   6400  O O   . GLU C 1 109 ? 59.859  -15.731 165.564 1.00 59.04  ? 128 GLU C O   1 
ATOM   6401  C CB  . GLU C 1 109 ? 56.719  -16.772 165.712 1.00 54.54  ? 128 GLU C CB  1 
ATOM   6402  C CG  . GLU C 1 109 ? 56.138  -17.985 166.472 1.00 53.93  ? 128 GLU C CG  1 
ATOM   6403  C CD  . GLU C 1 109 ? 55.044  -18.756 165.643 1.00 53.62  ? 128 GLU C CD  1 
ATOM   6404  O OE1 . GLU C 1 109 ? 53.918  -18.163 165.425 1.00 52.18  ? 128 GLU C OE1 1 
ATOM   6405  O OE2 . GLU C 1 109 ? 55.334  -19.935 165.199 1.00 55.19  ? 128 GLU C OE2 1 
ATOM   6406  N N   . TYR C 1 110 ? 58.357  -14.284 164.763 1.00 52.50  ? 129 TYR C N   1 
ATOM   6407  C CA  . TYR C 1 110 ? 59.336  -13.677 163.862 1.00 54.32  ? 129 TYR C CA  1 
ATOM   6408  C C   . TYR C 1 110 ? 60.491  -13.076 164.657 1.00 56.14  ? 129 TYR C C   1 
ATOM   6409  O O   . TYR C 1 110 ? 61.649  -13.150 164.231 1.00 57.86  ? 129 TYR C O   1 
ATOM   6410  C CB  . TYR C 1 110 ? 58.674  -12.609 162.958 1.00 53.51  ? 129 TYR C CB  1 
ATOM   6411  C CG  . TYR C 1 110 ? 59.585  -12.111 161.836 1.00 55.67  ? 129 TYR C CG  1 
ATOM   6412  C CD1 . TYR C 1 110 ? 59.788  -12.867 160.696 1.00 56.45  ? 129 TYR C CD1 1 
ATOM   6413  C CD2 . TYR C 1 110 ? 60.274  -10.909 161.946 1.00 56.45  ? 129 TYR C CD2 1 
ATOM   6414  C CE1 . TYR C 1 110 ? 60.631  -12.432 159.693 1.00 58.80  ? 129 TYR C CE1 1 
ATOM   6415  C CE2 . TYR C 1 110 ? 61.130  -10.476 160.947 1.00 58.81  ? 129 TYR C CE2 1 
ATOM   6416  C CZ  . TYR C 1 110 ? 61.297  -11.246 159.820 1.00 59.74  ? 129 TYR C CZ  1 
ATOM   6417  O OH  . TYR C 1 110 ? 62.139  -10.860 158.810 1.00 62.20  ? 129 TYR C OH  1 
ATOM   6418  N N   . ALA C 1 111 ? 60.190  -12.499 165.834 1.00 58.11  ? 130 ALA C N   1 
ATOM   6419  C CA  . ALA C 1 111 ? 61.220  -11.862 166.661 1.00 59.26  ? 130 ALA C CA  1 
ATOM   6420  C C   . ALA C 1 111 ? 62.257  -12.851 167.184 1.00 60.81  ? 130 ALA C C   1 
ATOM   6421  O O   . ALA C 1 111 ? 63.384  -12.457 167.505 1.00 62.55  ? 130 ALA C O   1 
ATOM   6422  C CB  . ALA C 1 111 ? 60.585  -11.144 167.856 1.00 58.26  ? 130 ALA C CB  1 
ATOM   6423  N N   . LYS C 1 112 ? 61.893  -14.125 167.333 1.00 61.43  ? 131 LYS C N   1 
ATOM   6424  C CA  . LYS C 1 112 ? 62.859  -15.121 167.771 1.00 62.94  ? 131 LYS C CA  1 
ATOM   6425  C C   . LYS C 1 112 ? 63.594  -15.786 166.610 1.00 64.47  ? 131 LYS C C   1 
ATOM   6426  O O   . LYS C 1 112 ? 64.290  -16.783 166.832 1.00 65.76  ? 131 LYS C O   1 
ATOM   6427  C CB  . LYS C 1 112 ? 62.182  -16.211 168.613 1.00 61.97  ? 131 LYS C CB  1 
ATOM   6428  C CG  . LYS C 1 112 ? 61.191  -15.747 169.684 1.00 61.15  ? 131 LYS C CG  1 
ATOM   6429  C CD  . LYS C 1 112 ? 60.270  -16.926 170.032 1.00 60.51  ? 131 LYS C CD  1 
ATOM   6430  C CE  . LYS C 1 112 ? 59.541  -16.763 171.355 1.00 60.89  ? 131 LYS C CE  1 
ATOM   6431  N NZ  . LYS C 1 112 ? 58.828  -18.037 171.777 1.00 60.72  ? 131 LYS C NZ  1 
ATOM   6432  N N   . HIS C 1 113 ? 63.464  -15.271 165.385 1.00 62.17  ? 132 HIS C N   1 
ATOM   6433  C CA  . HIS C 1 113 ? 64.183  -15.819 164.235 1.00 63.42  ? 132 HIS C CA  1 
ATOM   6434  C C   . HIS C 1 113 ? 64.955  -14.730 163.509 1.00 65.44  ? 132 HIS C C   1 
ATOM   6435  O O   . HIS C 1 113 ? 64.612  -14.349 162.383 1.00 64.86  ? 132 HIS C O   1 
ATOM   6436  C CB  . HIS C 1 113 ? 63.225  -16.526 163.277 1.00 62.33  ? 132 HIS C CB  1 
ATOM   6437  C CG  . HIS C 1 113 ? 62.643  -17.787 163.829 1.00 61.37  ? 132 HIS C CG  1 
ATOM   6438  N ND1 . HIS C 1 113 ? 63.339  -18.973 163.873 1.00 62.47  ? 132 HIS C ND1 1 
ATOM   6439  C CD2 . HIS C 1 113 ? 61.420  -18.040 164.354 1.00 59.68  ? 132 HIS C CD2 1 
ATOM   6440  C CE1 . HIS C 1 113 ? 62.570  -19.905 164.410 1.00 61.49  ? 132 HIS C CE1 1 
ATOM   6441  N NE2 . HIS C 1 113 ? 61.401  -19.364 164.709 1.00 60.03  ? 132 HIS C NE2 1 
ATOM   6442  N N   . PRO C 1 114 ? 66.029  -14.231 164.117 1.00 61.84  ? 133 PRO C N   1 
ATOM   6443  C CA  . PRO C 1 114 ? 66.855  -13.219 163.436 1.00 63.88  ? 133 PRO C CA  1 
ATOM   6444  C C   . PRO C 1 114 ? 67.677  -13.775 162.293 1.00 65.49  ? 133 PRO C C   1 
ATOM   6445  O O   . PRO C 1 114 ? 68.159  -12.995 161.461 1.00 66.68  ? 133 PRO C O   1 
ATOM   6446  C CB  . PRO C 1 114 ? 67.773  -12.679 164.543 1.00 65.40  ? 133 PRO C CB  1 
ATOM   6447  C CG  . PRO C 1 114 ? 67.419  -13.400 165.807 1.00 65.00  ? 133 PRO C CG  1 
ATOM   6448  C CD  . PRO C 1 114 ? 66.364  -14.423 165.537 1.00 63.05  ? 133 PRO C CD  1 
ATOM   6449  N N   . GLN C 1 115 ? 67.876  -15.092 162.238 1.00 65.88  ? 134 GLN C N   1 
ATOM   6450  C CA  . GLN C 1 115 ? 68.569  -15.681 161.103 1.00 67.51  ? 134 GLN C CA  1 
ATOM   6451  C C   . GLN C 1 115 ? 67.817  -15.449 159.810 1.00 66.52  ? 134 GLN C C   1 
ATOM   6452  O O   . GLN C 1 115 ? 68.400  -15.627 158.738 1.00 68.36  ? 134 GLN C O   1 
ATOM   6453  C CB  . GLN C 1 115 ? 68.767  -17.177 161.339 1.00 68.35  ? 134 GLN C CB  1 
ATOM   6454  C CG  . GLN C 1 115 ? 67.455  -17.965 161.507 1.00 67.19  ? 134 GLN C CG  1 
ATOM   6455  C CD  . GLN C 1 115 ? 67.102  -18.259 162.972 1.00 66.48  ? 134 GLN C CD  1 
ATOM   6456  O OE1 . GLN C 1 115 ? 67.444  -17.480 163.880 1.00 65.84  ? 134 GLN C OE1 1 
ATOM   6457  N NE2 . GLN C 1 115 ? 66.410  -19.389 163.205 1.00 65.66  ? 134 GLN C NE2 1 
ATOM   6458  N N   . TRP C 1 116 ? 66.533  -15.062 159.897 1.00 65.95  ? 135 TRP C N   1 
ATOM   6459  C CA  . TRP C 1 116 ? 65.727  -14.724 158.725 1.00 65.44  ? 135 TRP C CA  1 
ATOM   6460  C C   . TRP C 1 116 ? 65.731  -13.230 158.398 1.00 66.30  ? 135 TRP C C   1 
ATOM   6461  O O   . TRP C 1 116 ? 65.521  -12.867 157.238 1.00 66.59  ? 135 TRP C O   1 
ATOM   6462  C CB  . TRP C 1 116 ? 64.254  -15.166 158.898 1.00 62.75  ? 135 TRP C CB  1 
ATOM   6463  C CG  . TRP C 1 116 ? 64.008  -16.641 159.275 1.00 61.27  ? 135 TRP C CG  1 
ATOM   6464  C CD1 . TRP C 1 116 ? 64.872  -17.677 159.140 1.00 62.11  ? 135 TRP C CD1 1 
ATOM   6465  C CD2 . TRP C 1 116 ? 62.810  -17.193 159.858 1.00 58.69  ? 135 TRP C CD2 1 
ATOM   6466  N NE1 . TRP C 1 116 ? 64.297  -18.838 159.615 1.00 60.55  ? 135 TRP C NE1 1 
ATOM   6467  C CE2 . TRP C 1 116 ? 63.034  -18.561 160.061 1.00 58.52  ? 135 TRP C CE2 1 
ATOM   6468  C CE3 . TRP C 1 116 ? 61.580  -16.649 160.245 1.00 57.11  ? 135 TRP C CE3 1 
ATOM   6469  C CZ2 . TRP C 1 116 ? 62.086  -19.392 160.624 1.00 56.81  ? 135 TRP C CZ2 1 
ATOM   6470  C CZ3 . TRP C 1 116 ? 60.632  -17.488 160.794 1.00 55.47  ? 135 TRP C CZ3 1 
ATOM   6471  C CH2 . TRP C 1 116 ? 60.891  -18.843 160.976 1.00 55.34  ? 135 TRP C CH2 1 
ATOM   6472  N N   . TRP C 1 117 ? 65.994  -12.364 159.375 1.00 65.83  ? 136 TRP C N   1 
ATOM   6473  C CA  . TRP C 1 117 ? 65.754  -10.936 159.209 1.00 65.42  ? 136 TRP C CA  1 
ATOM   6474  C C   . TRP C 1 117 ? 66.493  -10.330 158.024 1.00 68.09  ? 136 TRP C C   1 
ATOM   6475  O O   . TRP C 1 117 ? 67.666  -10.618 157.780 1.00 70.42  ? 136 TRP C O   1 
ATOM   6476  C CB  . TRP C 1 117 ? 66.166  -10.196 160.469 1.00 65.20  ? 136 TRP C CB  1 
ATOM   6477  C CG  . TRP C 1 117 ? 65.341  -10.528 161.637 1.00 63.17  ? 136 TRP C CG  1 
ATOM   6478  C CD1 . TRP C 1 117 ? 64.234  -11.332 161.667 1.00 61.37  ? 136 TRP C CD1 1 
ATOM   6479  C CD2 . TRP C 1 117 ? 65.549  -10.071 162.983 1.00 62.52  ? 136 TRP C CD2 1 
ATOM   6480  N NE1 . TRP C 1 117 ? 63.731  -11.392 162.950 1.00 59.98  ? 136 TRP C NE1 1 
ATOM   6481  C CE2 . TRP C 1 117 ? 64.530  -10.638 163.778 1.00 60.69  ? 136 TRP C CE2 1 
ATOM   6482  C CE3 . TRP C 1 117 ? 66.492  -9.234  163.588 1.00 64.08  ? 136 TRP C CE3 1 
ATOM   6483  C CZ2 . TRP C 1 117 ? 64.437  -10.393 165.150 1.00 60.46  ? 136 TRP C CZ2 1 
ATOM   6484  C CZ3 . TRP C 1 117 ? 66.401  -9.003  164.950 1.00 63.49  ? 136 TRP C CZ3 1 
ATOM   6485  C CH2 . TRP C 1 117 ? 65.378  -9.571  165.714 1.00 62.04  ? 136 TRP C CH2 1 
ATOM   6486  N N   . LEU C 1 118 ? 65.797  -9.438  157.319 1.00 64.32  ? 137 LEU C N   1 
ATOM   6487  C CA  . LEU C 1 118 ? 66.329  -8.836  156.110 1.00 66.69  ? 137 LEU C CA  1 
ATOM   6488  C C   . LEU C 1 118 ? 67.290  -7.705  156.438 1.00 67.52  ? 137 LEU C C   1 
ATOM   6489  O O   . LEU C 1 118 ? 66.965  -6.802  157.214 1.00 65.49  ? 137 LEU C O   1 
ATOM   6490  C CB  . LEU C 1 118 ? 65.209  -8.294  155.236 1.00 65.26  ? 137 LEU C CB  1 
ATOM   6491  C CG  . LEU C 1 118 ? 65.756  -7.699  153.942 1.00 67.19  ? 137 LEU C CG  1 
ATOM   6492  C CD1 . LEU C 1 118 ? 66.497  -8.699  153.078 1.00 69.70  ? 137 LEU C CD1 1 
ATOM   6493  C CD2 . LEU C 1 118 ? 64.587  -7.106  153.182 1.00 64.10  ? 137 LEU C CD2 1 
ATOM   6494  N N   . ARG C 1 119 ? 68.456  -7.739  155.807 1.00 70.86  ? 138 ARG C N   1 
ATOM   6495  C CA  . ARG C 1 119 ? 69.482  -6.727  155.965 1.00 71.97  ? 138 ARG C CA  1 
ATOM   6496  C C   . ARG C 1 119 ? 69.786  -6.116  154.605 1.00 73.50  ? 138 ARG C C   1 
ATOM   6497  O O   . ARG C 1 119 ? 69.515  -6.697  153.547 1.00 74.92  ? 138 ARG C O   1 
ATOM   6498  C CB  . ARG C 1 119 ? 70.767  -7.309  156.590 1.00 73.96  ? 138 ARG C CB  1 
ATOM   6499  N N   . THR C 1 120 ? 70.335  -4.915  154.662 1.00 79.00  ? 139 THR C N   1 
ATOM   6500  C CA  . THR C 1 120 ? 70.830  -4.218  153.481 1.00 80.40  ? 139 THR C CA  1 
ATOM   6501  C C   . THR C 1 120 ? 72.207  -4.771  153.107 1.00 83.08  ? 139 THR C C   1 
ATOM   6502  O O   . THR C 1 120 ? 72.710  -5.741  153.688 1.00 83.70  ? 139 THR C O   1 
ATOM   6503  C CB  . THR C 1 120 ? 70.908  -2.719  153.750 1.00 79.49  ? 139 THR C CB  1 
ATOM   6504  O OG1 . THR C 1 120 ? 71.942  -2.496  154.723 1.00 80.30  ? 139 THR C OG1 1 
ATOM   6505  C CG2 . THR C 1 120 ? 69.569  -2.209  154.265 1.00 76.63  ? 139 THR C CG2 1 
ATOM   6506  N N   . THR C 1 121 ? 72.841  -4.144  152.116 1.00 82.86  ? 140 THR C N   1 
ATOM   6507  C CA  . THR C 1 121 ? 74.183  -4.547  151.720 1.00 85.11  ? 140 THR C CA  1 
ATOM   6508  C C   . THR C 1 121 ? 75.172  -4.354  152.866 1.00 85.39  ? 140 THR C C   1 
ATOM   6509  O O   . THR C 1 121 ? 76.123  -5.140  153.016 1.00 87.23  ? 140 THR C O   1 
ATOM   6510  C CB  . THR C 1 121 ? 74.610  -3.734  150.491 1.00 86.13  ? 140 THR C CB  1 
ATOM   6511  O OG1 . THR C 1 121 ? 74.565  -2.330  150.805 1.00 85.02  ? 140 THR C OG1 1 
ATOM   6512  C CG2 . THR C 1 121 ? 73.680  -4.009  149.295 1.00 86.54  ? 140 THR C CG2 1 
ATOM   6513  N N   . THR C 1 122 ? 74.943  -3.322  153.693 1.00 85.10  ? 141 THR C N   1 
ATOM   6514  C CA  . THR C 1 122 ? 75.828  -2.962  154.786 1.00 86.93  ? 141 THR C CA  1 
ATOM   6515  C C   . THR C 1 122 ? 75.637  -3.803  156.033 1.00 85.97  ? 141 THR C C   1 
ATOM   6516  O O   . THR C 1 122 ? 76.453  -3.700  156.958 1.00 87.74  ? 141 THR C O   1 
ATOM   6517  C CB  . THR C 1 122 ? 75.597  -1.502  155.156 1.00 87.05  ? 141 THR C CB  1 
ATOM   6518  O OG1 . THR C 1 122 ? 74.361  -1.374  155.870 1.00 84.85  ? 141 THR C OG1 1 
ATOM   6519  C CG2 . THR C 1 122 ? 75.518  -0.682  153.910 1.00 87.70  ? 141 THR C CG2 1 
ATOM   6520  N N   . GLY C 1 123 ? 74.590  -4.614  156.090 1.00 86.60  ? 142 GLY C N   1 
ATOM   6521  C CA  . GLY C 1 123 ? 74.225  -5.300  157.300 1.00 85.21  ? 142 GLY C CA  1 
ATOM   6522  C C   . GLY C 1 123 ? 73.194  -4.584  158.150 1.00 83.41  ? 142 GLY C C   1 
ATOM   6523  O O   . GLY C 1 123 ? 72.569  -5.225  159.012 1.00 82.54  ? 142 GLY C O   1 
ATOM   6524  N N   . GLU C 1 124 ? 72.996  -3.282  157.942 1.00 81.49  ? 143 GLU C N   1 
ATOM   6525  C CA  . GLU C 1 124 ? 71.908  -2.582  158.610 1.00 80.06  ? 143 GLU C CA  1 
ATOM   6526  C C   . GLU C 1 124 ? 70.605  -3.331  158.354 1.00 77.20  ? 143 GLU C C   1 
ATOM   6527  O O   . GLU C 1 124 ? 70.270  -3.651  157.211 1.00 77.26  ? 143 GLU C O   1 
ATOM   6528  C CB  . GLU C 1 124 ? 71.810  -1.134  158.117 1.00 80.70  ? 143 GLU C CB  1 
ATOM   6529  N N   . LEU C 1 125 ? 69.903  -3.656  159.431 1.00 75.98  ? 144 LEU C N   1 
ATOM   6530  C CA  . LEU C 1 125 ? 68.611  -4.303  159.317 1.00 73.43  ? 144 LEU C CA  1 
ATOM   6531  C C   . LEU C 1 125 ? 67.655  -3.449  158.497 1.00 71.90  ? 144 LEU C C   1 
ATOM   6532  O O   . LEU C 1 125 ? 67.540  -2.242  158.710 1.00 72.11  ? 144 LEU C O   1 
ATOM   6533  C CB  . LEU C 1 125 ? 68.042  -4.553  160.705 1.00 72.48  ? 144 LEU C CB  1 
ATOM   6534  C CG  . LEU C 1 125 ? 68.875  -5.470  161.596 1.00 73.98  ? 144 LEU C CG  1 
ATOM   6535  C CD1 . LEU C 1 125 ? 68.284  -5.466  162.997 1.00 73.44  ? 144 LEU C CD1 1 
ATOM   6536  C CD2 . LEU C 1 125 ? 68.943  -6.881  161.043 1.00 74.14  ? 144 LEU C CD2 1 
ATOM   6537  N N   . ASP C 1 126 ? 66.960  -4.075  157.560 1.00 71.60  ? 145 ASP C N   1 
ATOM   6538  C CA  . ASP C 1 126 ? 65.992  -3.334  156.758 1.00 69.92  ? 145 ASP C CA  1 
ATOM   6539  C C   . ASP C 1 126 ? 64.673  -3.263  157.514 1.00 67.28  ? 145 ASP C C   1 
ATOM   6540  O O   . ASP C 1 126 ? 63.904  -4.226  157.560 1.00 65.49  ? 145 ASP C O   1 
ATOM   6541  C CB  . ASP C 1 126 ? 65.790  -3.964  155.390 1.00 70.06  ? 145 ASP C CB  1 
ATOM   6542  C CG  . ASP C 1 126 ? 64.988  -3.068  154.470 1.00 68.88  ? 145 ASP C CG  1 
ATOM   6543  O OD1 . ASP C 1 126 ? 64.279  -2.171  155.001 1.00 67.09  ? 145 ASP C OD1 1 
ATOM   6544  O OD2 . ASP C 1 126 ? 65.070  -3.245  153.235 1.00 69.85  ? 145 ASP C OD2 1 
ATOM   6545  N N   . ARG C 1 127 ? 64.422  -2.115  158.125 1.00 71.51  ? 146 ARG C N   1 
ATOM   6546  C CA  . ARG C 1 127 ? 63.156  -1.773  158.751 1.00 69.84  ? 146 ARG C CA  1 
ATOM   6547  C C   . ARG C 1 127 ? 62.556  -0.597  157.972 1.00 69.89  ? 146 ARG C C   1 
ATOM   6548  O O   . ARG C 1 127 ? 63.236  0.046   157.157 1.00 71.93  ? 146 ARG C O   1 
ATOM   6549  C CB  . ARG C 1 127 ? 63.340  -1.414  160.226 1.00 70.98  ? 146 ARG C CB  1 
ATOM   6550  C CG  . ARG C 1 127 ? 64.037  -2.424  161.154 1.00 71.66  ? 146 ARG C CG  1 
ATOM   6551  C CD  . ARG C 1 127 ? 64.191  -1.784  162.587 1.00 72.69  ? 146 ARG C CD  1 
ATOM   6552  N NE  . ARG C 1 127 ? 63.669  -2.632  163.661 1.00 72.14  ? 146 ARG C NE  1 
ATOM   6553  C CZ  . ARG C 1 127 ? 64.255  -3.733  164.127 1.00 72.82  ? 146 ARG C CZ  1 
ATOM   6554  N NH1 . ARG C 1 127 ? 65.459  -4.110  163.710 1.00 74.26  ? 146 ARG C NH1 1 
ATOM   6555  N NH2 . ARG C 1 127 ? 63.602  -4.495  165.007 1.00 72.87  ? 146 ARG C NH2 1 
ATOM   6556  N N   . LYS C 1 128 ? 61.273  -0.307  158.224 1.00 66.46  ? 147 LYS C N   1 
ATOM   6557  C CA  . LYS C 1 128 ? 60.644  0.897   157.716 1.00 66.61  ? 147 LYS C CA  1 
ATOM   6558  C C   . LYS C 1 128 ? 60.614  1.984   158.790 1.00 68.28  ? 147 LYS C C   1 
ATOM   6559  O O   . LYS C 1 128 ? 61.032  1.781   159.941 1.00 69.42  ? 147 LYS C O   1 
ATOM   6560  C CB  . LYS C 1 128 ? 59.226  0.626   157.227 1.00 64.42  ? 147 LYS C CB  1 
ATOM   6561  C CG  . LYS C 1 128 ? 59.194  -0.168  155.981 1.00 64.22  ? 147 LYS C CG  1 
ATOM   6562  C CD  . LYS C 1 128 ? 57.803  -0.253  155.417 1.00 62.19  ? 147 LYS C CD  1 
ATOM   6563  C CE  . LYS C 1 128 ? 57.339  1.060   154.846 1.00 62.99  ? 147 LYS C CE  1 
ATOM   6564  N NZ  . LYS C 1 128 ? 55.847  1.133   154.840 1.00 61.76  ? 147 LYS C NZ  1 
ATOM   6565  N N   . LYS C 1 129 ? 60.150  3.175   158.384 1.00 68.59  ? 148 LYS C N   1 
ATOM   6566  C CA  . LYS C 1 129 ? 60.006  4.268   159.338 1.00 70.74  ? 148 LYS C CA  1 
ATOM   6567  C C   . LYS C 1 129 ? 59.435  3.707   160.638 1.00 70.23  ? 148 LYS C C   1 
ATOM   6568  O O   . LYS C 1 129 ? 59.990  3.920   161.736 1.00 73.63  ? 148 LYS C O   1 
ATOM   6569  C CB  . LYS C 1 129 ? 59.105  5.357   158.764 1.00 71.26  ? 148 LYS C CB  1 
ATOM   6570  N N   . GLY C 1 130 ? 58.369  2.888   160.497 1.00 71.09  ? 149 GLY C N   1 
ATOM   6571  C CA  . GLY C 1 130 ? 57.608  2.374   161.621 1.00 70.28  ? 149 GLY C CA  1 
ATOM   6572  C C   . GLY C 1 130 ? 58.336  1.397   162.524 1.00 71.30  ? 149 GLY C C   1 
ATOM   6573  O O   . GLY C 1 130 ? 57.681  0.563   163.163 1.00 70.46  ? 149 GLY C O   1 
ATOM   6574  N N   . GLN C 1 131 ? 59.668  1.497   162.617 1.00 67.86  ? 150 GLN C N   1 
ATOM   6575  C CA  . GLN C 1 131 ? 60.482  0.413   163.173 1.00 69.02  ? 150 GLN C CA  1 
ATOM   6576  C C   . GLN C 1 131 ? 59.892  -0.950  162.752 1.00 66.48  ? 150 GLN C C   1 
ATOM   6577  O O   . GLN C 1 131 ? 59.623  -1.830  163.563 1.00 66.63  ? 150 GLN C O   1 
ATOM   6578  C CB  . GLN C 1 131 ? 60.593  0.584   164.680 1.00 70.96  ? 150 GLN C CB  1 
ATOM   6579  N N   . LEU C 1 132 ? 59.706  -1.107  161.438 1.00 65.32  ? 151 LEU C N   1 
ATOM   6580  C CA  . LEU C 1 132 ? 58.929  -2.189  160.841 1.00 62.50  ? 151 LEU C CA  1 
ATOM   6581  C C   . LEU C 1 132 ? 59.808  -3.040  159.927 1.00 62.51  ? 151 LEU C C   1 
ATOM   6582  O O   . LEU C 1 132 ? 60.066  -2.686  158.769 1.00 62.99  ? 151 LEU C O   1 
ATOM   6583  C CB  . LEU C 1 132 ? 57.761  -1.613  160.057 1.00 60.70  ? 151 LEU C CB  1 
ATOM   6584  C CG  . LEU C 1 132 ? 56.411  -2.320  160.163 1.00 59.46  ? 151 LEU C CG  1 
ATOM   6585  C CD1 . LEU C 1 132 ? 55.876  -2.444  161.577 1.00 60.35  ? 151 LEU C CD1 1 
ATOM   6586  C CD2 . LEU C 1 132 ? 55.450  -1.517  159.256 1.00 58.84  ? 151 LEU C CD2 1 
ATOM   6587  N N   . MET C 1 133 ? 60.234  -4.189  160.433 1.00 58.09  ? 152 MET C N   1 
ATOM   6588  C CA  . MET C 1 133 ? 61.152  -5.021  159.682 1.00 58.89  ? 152 MET C CA  1 
ATOM   6589  C C   . MET C 1 133 ? 60.497  -5.501  158.395 1.00 57.46  ? 152 MET C C   1 
ATOM   6590  O O   . MET C 1 133 ? 59.297  -5.789  158.346 1.00 55.31  ? 152 MET C O   1 
ATOM   6591  C CB  . MET C 1 133 ? 61.581  -6.192  160.542 1.00 60.24  ? 152 MET C CB  1 
ATOM   6592  C CG  . MET C 1 133 ? 62.856  -5.940  161.262 1.00 63.42  ? 152 MET C CG  1 
ATOM   6593  S SD  . MET C 1 133 ? 63.442  -7.331  162.252 1.00 63.78  ? 152 MET C SD  1 
ATOM   6594  C CE  . MET C 1 133 ? 62.056  -7.768  163.308 1.00 61.98  ? 152 MET C CE  1 
ATOM   6595  N N   . ARG C 1 134 ? 61.286  -5.575  157.342 1.00 56.80  ? 153 ARG C N   1 
ATOM   6596  C CA  . ARG C 1 134 ? 60.809  -6.124  156.087 1.00 55.55  ? 153 ARG C CA  1 
ATOM   6597  C C   . ARG C 1 134 ? 61.328  -7.553  155.931 1.00 56.79  ? 153 ARG C C   1 
ATOM   6598  O O   . ARG C 1 134 ? 62.392  -7.925  156.435 1.00 59.91  ? 153 ARG C O   1 
ATOM   6599  C CB  . ARG C 1 134 ? 61.204  -5.224  154.911 1.00 56.69  ? 153 ARG C CB  1 
ATOM   6600  C CG  . ARG C 1 134 ? 60.775  -3.731  155.142 1.00 56.19  ? 153 ARG C CG  1 
ATOM   6601  C CD  . ARG C 1 134 ? 60.658  -2.866  153.886 1.00 56.57  ? 153 ARG C CD  1 
ATOM   6602  N NE  . ARG C 1 134 ? 61.909  -2.702  153.151 1.00 59.30  ? 153 ARG C NE  1 
ATOM   6603  C CZ  . ARG C 1 134 ? 61.981  -2.234  151.913 1.00 60.13  ? 153 ARG C CZ  1 
ATOM   6604  N NH1 . ARG C 1 134 ? 60.901  -1.828  151.270 1.00 58.25  ? 153 ARG C NH1 1 
ATOM   6605  N NH2 . ARG C 1 134 ? 63.161  -2.199  151.299 1.00 62.86  ? 153 ARG C NH2 1 
ATOM   6606  N N   . TYR C 1 135 ? 60.504  -8.367  155.285 1.00 56.03  ? 154 TYR C N   1 
ATOM   6607  C CA  . TYR C 1 135 ? 60.757  -9.781  155.191 1.00 56.62  ? 154 TYR C CA  1 
ATOM   6608  C C   . TYR C 1 135 ? 61.711  -10.070 154.043 1.00 57.83  ? 154 TYR C C   1 
ATOM   6609  O O   . TYR C 1 135 ? 61.754  -9.348  153.046 1.00 57.54  ? 154 TYR C O   1 
ATOM   6610  C CB  . TYR C 1 135 ? 59.446  -10.534 154.961 1.00 52.90  ? 154 TYR C CB  1 
ATOM   6611  C CG  . TYR C 1 135 ? 58.436  -10.539 156.098 1.00 51.51  ? 154 TYR C CG  1 
ATOM   6612  C CD1 . TYR C 1 135 ? 58.823  -10.656 157.423 1.00 53.53  ? 154 TYR C CD1 1 
ATOM   6613  C CD2 . TYR C 1 135 ? 57.083  -10.455 155.825 1.00 48.58  ? 154 TYR C CD2 1 
ATOM   6614  C CE1 . TYR C 1 135 ? 57.878  -10.683 158.429 1.00 52.26  ? 154 TYR C CE1 1 
ATOM   6615  C CE2 . TYR C 1 135 ? 56.152  -10.486 156.827 1.00 47.54  ? 154 TYR C CE2 1 
ATOM   6616  C CZ  . TYR C 1 135 ? 56.547  -10.615 158.117 1.00 49.33  ? 154 TYR C CZ  1 
ATOM   6617  O OH  . TYR C 1 135 ? 55.588  -10.655 159.094 1.00 48.92  ? 154 TYR C OH  1 
ATOM   6618  N N   . ASP C 1 136 ? 62.472  -11.155 154.189 1.00 57.00  ? 155 ASP C N   1 
ATOM   6619  C CA  . ASP C 1 136 ? 63.417  -11.592 153.163 1.00 57.58  ? 155 ASP C CA  1 
ATOM   6620  C C   . ASP C 1 136 ? 62.731  -12.720 152.408 1.00 54.17  ? 155 ASP C C   1 
ATOM   6621  O O   . ASP C 1 136 ? 62.925  -13.907 152.698 1.00 54.27  ? 155 ASP C O   1 
ATOM   6622  C CB  . ASP C 1 136 ? 64.751  -12.054 153.748 1.00 60.91  ? 155 ASP C CB  1 
ATOM   6623  C CG  . ASP C 1 136 ? 65.740  -12.529 152.661 1.00 62.33  ? 155 ASP C CG  1 
ATOM   6624  O OD1 . ASP C 1 136 ? 65.360  -12.581 151.464 1.00 60.71  ? 155 ASP C OD1 1 
ATOM   6625  O OD2 . ASP C 1 136 ? 66.904  -12.841 153.007 1.00 65.30  ? 155 ASP C OD2 1 
ATOM   6626  N N   . LEU C 1 137 ? 61.940  -12.359 151.413 1.00 56.66  ? 156 LEU C N   1 
ATOM   6627  C CA  . LEU C 1 137 ? 61.134  -13.371 150.738 1.00 54.03  ? 156 LEU C CA  1 
ATOM   6628  C C   . LEU C 1 137 ? 61.984  -14.474 150.117 1.00 55.22  ? 156 LEU C C   1 
ATOM   6629  O O   . LEU C 1 137 ? 61.448  -15.523 149.777 1.00 53.64  ? 156 LEU C O   1 
ATOM   6630  C CB  . LEU C 1 137 ? 60.245  -12.704 149.682 1.00 52.79  ? 156 LEU C CB  1 
ATOM   6631  C CG  . LEU C 1 137 ? 59.311  -11.616 150.221 1.00 52.21  ? 156 LEU C CG  1 
ATOM   6632  C CD1 . LEU C 1 137 ? 58.407  -11.189 149.082 1.00 50.77  ? 156 LEU C CD1 1 
ATOM   6633  C CD2 . LEU C 1 137 ? 58.442  -11.997 151.396 1.00 51.04  ? 156 LEU C CD2 1 
ATOM   6634  N N   . SER C 1 138 ? 63.289  -14.270 149.965 1.00 53.97  ? 157 SER C N   1 
ATOM   6635  C CA  . SER C 1 138 ? 64.175  -15.285 149.411 1.00 55.25  ? 157 SER C CA  1 
ATOM   6636  C C   . SER C 1 138 ? 64.544  -16.341 150.434 1.00 55.36  ? 157 SER C C   1 
ATOM   6637  O O   . SER C 1 138 ? 65.210  -17.313 150.089 1.00 56.58  ? 157 SER C O   1 
ATOM   6638  C CB  . SER C 1 138 ? 65.442  -14.635 148.849 1.00 58.94  ? 157 SER C CB  1 
ATOM   6639  O OG  . SER C 1 138 ? 66.298  -14.177 149.882 1.00 61.35  ? 157 SER C OG  1 
ATOM   6640  N N   . ASN C 1 139 ? 64.110  -16.184 151.677 1.00 55.93  ? 158 ASN C N   1 
ATOM   6641  C CA  . ASN C 1 139 ? 64.447  -17.120 152.740 1.00 56.27  ? 158 ASN C CA  1 
ATOM   6642  C C   . ASN C 1 139 ? 63.367  -18.182 152.811 1.00 53.67  ? 158 ASN C C   1 
ATOM   6643  O O   . ASN C 1 139 ? 62.204  -17.877 153.088 1.00 51.59  ? 158 ASN C O   1 
ATOM   6644  C CB  . ASN C 1 139 ? 64.580  -16.423 154.097 1.00 57.69  ? 158 ASN C CB  1 
ATOM   6645  C CG  . ASN C 1 139 ? 65.082  -17.357 155.200 1.00 58.51  ? 158 ASN C CG  1 
ATOM   6646  O OD1 . ASN C 1 139 ? 64.498  -18.418 155.474 1.00 56.91  ? 158 ASN C OD1 1 
ATOM   6647  N ND2 . ASN C 1 139 ? 66.151  -16.944 155.856 1.00 61.56  ? 158 ASN C ND2 1 
ATOM   6648  N N   . ALA C 1 140 ? 63.770  -19.430 152.638 1.00 57.02  ? 159 ALA C N   1 
ATOM   6649  C CA  . ALA C 1 140 ? 62.797  -20.502 152.530 1.00 54.59  ? 159 ALA C CA  1 
ATOM   6650  C C   . ALA C 1 140 ? 62.274  -20.930 153.885 1.00 53.90  ? 159 ALA C C   1 
ATOM   6651  O O   . ALA C 1 140 ? 61.099  -21.275 154.003 1.00 52.01  ? 159 ALA C O   1 
ATOM   6652  C CB  . ALA C 1 140 ? 63.424  -21.682 151.797 1.00 55.71  ? 159 ALA C CB  1 
ATOM   6653  N N   . GLU C 1 141 ? 63.099  -20.893 154.918 1.00 55.11  ? 160 GLU C N   1 
ATOM   6654  C CA  . GLU C 1 141 ? 62.564  -21.174 156.239 1.00 54.74  ? 160 GLU C CA  1 
ATOM   6655  C C   . GLU C 1 141 ? 61.547  -20.115 156.647 1.00 53.10  ? 160 GLU C C   1 
ATOM   6656  O O   . GLU C 1 141 ? 60.514  -20.436 157.250 1.00 51.43  ? 160 GLU C O   1 
ATOM   6657  C CB  . GLU C 1 141 ? 63.691  -21.238 157.264 1.00 58.04  ? 160 GLU C CB  1 
ATOM   6658  C CG  . GLU C 1 141 ? 64.523  -22.527 157.272 1.00 60.88  ? 160 GLU C CG  1 
ATOM   6659  C CD  . GLU C 1 141 ? 65.604  -22.437 158.328 1.00 64.69  ? 160 GLU C CD  1 
ATOM   6660  O OE1 . GLU C 1 141 ? 65.419  -21.586 159.237 1.00 65.07  ? 160 GLU C OE1 1 
ATOM   6661  O OE2 . GLU C 1 141 ? 66.620  -23.176 158.255 1.00 67.46  ? 160 GLU C OE2 1 
ATOM   6662  N N   . PHE C 1 142 ? 61.817  -18.835 156.319 1.00 55.21  ? 161 PHE C N   1 
ATOM   6663  C CA  . PHE C 1 142 ? 60.825  -17.780 156.522 1.00 54.11  ? 161 PHE C CA  1 
ATOM   6664  C C   . PHE C 1 142 ? 59.553  -18.050 155.724 1.00 51.14  ? 161 PHE C C   1 
ATOM   6665  O O   . PHE C 1 142 ? 58.445  -18.055 156.273 1.00 49.93  ? 161 PHE C O   1 
ATOM   6666  C CB  . PHE C 1 142 ? 61.376  -16.404 156.130 1.00 55.69  ? 161 PHE C CB  1 
ATOM   6667  C CG  . PHE C 1 142 ? 60.288  -15.430 155.772 1.00 53.66  ? 161 PHE C CG  1 
ATOM   6668  C CD1 . PHE C 1 142 ? 59.514  -14.843 156.765 1.00 53.69  ? 161 PHE C CD1 1 
ATOM   6669  C CD2 . PHE C 1 142 ? 59.997  -15.158 154.453 1.00 52.67  ? 161 PHE C CD2 1 
ATOM   6670  C CE1 . PHE C 1 142 ? 58.510  -14.005 156.451 1.00 52.20  ? 161 PHE C CE1 1 
ATOM   6671  C CE2 . PHE C 1 142 ? 58.991  -14.331 154.130 1.00 50.95  ? 161 PHE C CE2 1 
ATOM   6672  C CZ  . PHE C 1 142 ? 58.237  -13.750 155.131 1.00 50.61  ? 161 PHE C CZ  1 
ATOM   6673  N N   . ARG C 1 143 ? 59.682  -18.234 154.408 1.00 52.24  ? 162 ARG C N   1 
ATOM   6674  C CA  . ARG C 1 143 ? 58.491  -18.493 153.590 1.00 49.99  ? 162 ARG C CA  1 
ATOM   6675  C C   . ARG C 1 143 ? 57.651  -19.642 154.146 1.00 48.81  ? 162 ARG C C   1 
ATOM   6676  O O   . ARG C 1 143 ? 56.414  -19.587 154.135 1.00 46.87  ? 162 ARG C O   1 
ATOM   6677  C CB  . ARG C 1 143 ? 58.878  -18.825 152.150 1.00 49.92  ? 162 ARG C CB  1 
ATOM   6678  C CG  . ARG C 1 143 ? 59.422  -17.683 151.377 1.00 51.16  ? 162 ARG C CG  1 
ATOM   6679  C CD  . ARG C 1 143 ? 59.340  -17.956 149.897 1.00 50.92  ? 162 ARG C CD  1 
ATOM   6680  N NE  . ARG C 1 143 ? 59.958  -19.221 149.520 1.00 51.95  ? 162 ARG C NE  1 
ATOM   6681  C CZ  . ARG C 1 143 ? 61.224  -19.341 149.145 1.00 54.13  ? 162 ARG C CZ  1 
ATOM   6682  N NH1 . ARG C 1 143 ? 62.037  -18.295 149.120 1.00 56.56  ? 162 ARG C NH1 1 
ATOM   6683  N NH2 . ARG C 1 143 ? 61.686  -20.537 148.780 1.00 55.79  ? 162 ARG C NH2 1 
ATOM   6684  N N   . ASN C 1 144 ? 58.304  -20.715 154.602 1.00 49.49  ? 163 ASN C N   1 
ATOM   6685  C CA  . ASN C 1 144 ? 57.555  -21.815 155.199 1.00 48.77  ? 163 ASN C CA  1 
ATOM   6686  C C   . ASN C 1 144 ? 56.815  -21.342 156.444 1.00 48.34  ? 163 ASN C C   1 
ATOM   6687  O O   . ASN C 1 144 ? 55.636  -21.659 156.636 1.00 47.09  ? 163 ASN C O   1 
ATOM   6688  C CB  . ASN C 1 144 ? 58.489  -22.965 155.539 1.00 50.64  ? 163 ASN C CB  1 
ATOM   6689  C CG  . ASN C 1 144 ? 57.777  -24.082 156.216 1.00 50.90  ? 163 ASN C CG  1 
ATOM   6690  O OD1 . ASN C 1 144 ? 56.898  -24.715 155.641 1.00 49.99  ? 163 ASN C OD1 1 
ATOM   6691  N ND2 . ASN C 1 144 ? 58.132  -24.333 157.437 1.00 52.52  ? 163 ASN C ND2 1 
ATOM   6692  N N   . TRP C 1 145 ? 57.490  -20.553 157.292 1.00 48.46  ? 164 TRP C N   1 
ATOM   6693  C CA  . TRP C 1 145 ? 56.841  -20.076 158.508 1.00 48.34  ? 164 TRP C CA  1 
ATOM   6694  C C   . TRP C 1 145 ? 55.723  -19.100 158.167 1.00 46.65  ? 164 TRP C C   1 
ATOM   6695  O O   . TRP C 1 145 ? 54.662  -19.115 158.801 1.00 45.98  ? 164 TRP C O   1 
ATOM   6696  C CB  . TRP C 1 145 ? 57.867  -19.441 159.446 1.00 50.80  ? 164 TRP C CB  1 
ATOM   6697  C CG  . TRP C 1 145 ? 57.229  -18.584 160.527 1.00 50.86  ? 164 TRP C CG  1 
ATOM   6698  C CD1 . TRP C 1 145 ? 56.753  -19.001 161.745 1.00 51.27  ? 164 TRP C CD1 1 
ATOM   6699  C CD2 . TRP C 1 145 ? 56.992  -17.174 160.462 1.00 50.60  ? 164 TRP C CD2 1 
ATOM   6700  N NE1 . TRP C 1 145 ? 56.236  -17.933 162.440 1.00 51.26  ? 164 TRP C NE1 1 
ATOM   6701  C CE2 . TRP C 1 145 ? 56.367  -16.799 161.674 1.00 51.10  ? 164 TRP C CE2 1 
ATOM   6702  C CE3 . TRP C 1 145 ? 57.245  -16.192 159.499 1.00 51.06  ? 164 TRP C CE3 1 
ATOM   6703  C CZ2 . TRP C 1 145 ? 55.993  -15.473 161.947 1.00 51.53  ? 164 TRP C CZ2 1 
ATOM   6704  C CZ3 . TRP C 1 145 ? 56.876  -14.868 159.779 1.00 51.47  ? 164 TRP C CZ3 1 
ATOM   6705  C CH2 . TRP C 1 145 ? 56.260  -14.529 160.992 1.00 51.74  ? 164 TRP C CH2 1 
ATOM   6706  N N   . TRP C 1 146 ? 55.929  -18.262 157.152 1.00 48.56  ? 165 TRP C N   1 
ATOM   6707  C CA  . TRP C 1 146 ? 54.910  -17.265 156.799 1.00 47.23  ? 165 TRP C CA  1 
ATOM   6708  C C   . TRP C 1 146 ? 53.637  -17.947 156.312 1.00 45.19  ? 165 TRP C C   1 
ATOM   6709  O O   . TRP C 1 146 ? 52.528  -17.591 156.733 1.00 44.36  ? 165 TRP C O   1 
ATOM   6710  C CB  . TRP C 1 146 ? 55.472  -16.305 155.739 1.00 47.70  ? 165 TRP C CB  1 
ATOM   6711  C CG  . TRP C 1 146 ? 54.665  -15.072 155.465 1.00 46.59  ? 165 TRP C CG  1 
ATOM   6712  C CD1 . TRP C 1 146 ? 54.836  -13.831 156.024 1.00 47.49  ? 165 TRP C CD1 1 
ATOM   6713  C CD2 . TRP C 1 146 ? 53.576  -14.940 154.531 1.00 44.48  ? 165 TRP C CD2 1 
ATOM   6714  N NE1 . TRP C 1 146 ? 53.915  -12.952 155.506 1.00 46.11  ? 165 TRP C NE1 1 
ATOM   6715  C CE2 . TRP C 1 146 ? 53.132  -13.602 154.592 1.00 44.10  ? 165 TRP C CE2 1 
ATOM   6716  C CE3 . TRP C 1 146 ? 52.946  -15.819 153.652 1.00 43.40  ? 165 TRP C CE3 1 
ATOM   6717  C CZ2 . TRP C 1 146 ? 52.091  -13.138 153.824 1.00 42.87  ? 165 TRP C CZ2 1 
ATOM   6718  C CZ3 . TRP C 1 146 ? 51.918  -15.373 152.898 1.00 41.91  ? 165 TRP C CZ3 1 
ATOM   6719  C CH2 . TRP C 1 146 ? 51.489  -14.049 152.983 1.00 41.67  ? 165 TRP C CH2 1 
ATOM   6720  N N   . THR C 1 147 ? 53.779  -18.970 155.466 1.00 45.25  ? 166 THR C N   1 
ATOM   6721  C CA  . THR C 1 147 ? 52.598  -19.634 154.935 1.00 44.07  ? 166 THR C CA  1 
ATOM   6722  C C   . THR C 1 147 ? 51.914  -20.470 155.997 1.00 44.16  ? 166 THR C C   1 
ATOM   6723  O O   . THR C 1 147 ? 50.698  -20.667 155.940 1.00 43.40  ? 166 THR C O   1 
ATOM   6724  C CB  . THR C 1 147 ? 52.995  -20.473 153.743 1.00 44.27  ? 166 THR C CB  1 
ATOM   6725  O OG1 . THR C 1 147 ? 54.031  -21.374 154.143 1.00 45.71  ? 166 THR C OG1 1 
ATOM   6726  C CG2 . THR C 1 147 ? 53.493  -19.567 152.628 1.00 44.39  ? 166 THR C CG2 1 
ATOM   6727  N N   . ASN C 1 148 ? 52.664  -20.929 157.001 1.00 42.36  ? 167 ASN C N   1 
ATOM   6728  C CA  . ASN C 1 148 ? 52.030  -21.628 158.118 1.00 43.28  ? 167 ASN C CA  1 
ATOM   6729  C C   . ASN C 1 148 ? 51.117  -20.688 158.888 1.00 42.73  ? 167 ASN C C   1 
ATOM   6730  O O   . ASN C 1 148 ? 50.010  -21.063 159.286 1.00 42.80  ? 167 ASN C O   1 
ATOM   6731  C CB  . ASN C 1 148 ? 53.092  -22.255 159.024 1.00 45.37  ? 167 ASN C CB  1 
ATOM   6732  C CG  . ASN C 1 148 ? 53.601  -23.586 158.467 1.00 46.72  ? 167 ASN C CG  1 
ATOM   6733  O OD1 . ASN C 1 148 ? 53.021  -24.139 157.523 1.00 45.80  ? 167 ASN C OD1 1 
ATOM   6734  N ND2 . ASN C 1 148 ? 54.683  -24.095 159.031 1.00 49.16  ? 167 ASN C ND2 1 
ATOM   6735  N N   . VAL C 1 149 ? 51.540  -19.442 159.068 1.00 43.26  ? 168 VAL C N   1 
ATOM   6736  C CA  . VAL C 1 149 ? 50.663  -18.476 159.718 1.00 43.02  ? 168 VAL C CA  1 
ATOM   6737  C C   . VAL C 1 149 ? 49.368  -18.346 158.937 1.00 41.31  ? 168 VAL C C   1 
ATOM   6738  O O   . VAL C 1 149 ? 48.271  -18.508 159.481 1.00 41.22  ? 168 VAL C O   1 
ATOM   6739  C CB  . VAL C 1 149 ? 51.381  -17.124 159.893 1.00 43.78  ? 168 VAL C CB  1 
ATOM   6740  C CG1 . VAL C 1 149 ? 50.405  -16.042 160.420 1.00 43.87  ? 168 VAL C CG1 1 
ATOM   6741  C CG2 . VAL C 1 149 ? 52.612  -17.300 160.819 1.00 45.88  ? 168 VAL C CG2 1 
ATOM   6742  N N   . ALA C 1 150 ? 49.472  -18.122 157.635 1.00 41.81  ? 169 ALA C N   1 
ATOM   6743  C CA  . ALA C 1 150 ? 48.259  -18.009 156.826 1.00 40.64  ? 169 ALA C CA  1 
ATOM   6744  C C   . ALA C 1 150 ? 47.417  -19.276 156.913 1.00 40.56  ? 169 ALA C C   1 
ATOM   6745  O O   . ALA C 1 150 ? 46.199  -19.213 157.123 1.00 40.42  ? 169 ALA C O   1 
ATOM   6746  C CB  . ALA C 1 150 ? 48.631  -17.687 155.381 1.00 40.38  ? 169 ALA C CB  1 
ATOM   6747  N N   . ALA C 1 151 ? 48.052  -20.440 156.797 1.00 41.35  ? 170 ALA C N   1 
ATOM   6748  C CA  . ALA C 1 151 ? 47.276  -21.681 156.863 1.00 41.53  ? 170 ALA C CA  1 
ATOM   6749  C C   . ALA C 1 151 ? 46.594  -21.824 158.213 1.00 42.03  ? 170 ALA C C   1 
ATOM   6750  O O   . ALA C 1 151 ? 45.453  -22.286 158.286 1.00 42.54  ? 170 ALA C O   1 
ATOM   6751  C CB  . ALA C 1 151 ? 48.159  -22.898 156.549 1.00 42.21  ? 170 ALA C CB  1 
ATOM   6752  N N   . LYS C 1 152 ? 47.231  -21.374 159.289 1.00 43.53  ? 171 LYS C N   1 
ATOM   6753  C CA  . LYS C 1 152 ? 46.592  -21.530 160.587 1.00 44.45  ? 171 LYS C CA  1 
ATOM   6754  C C   . LYS C 1 152 ? 45.308  -20.725 160.658 1.00 43.73  ? 171 LYS C C   1 
ATOM   6755  O O   . LYS C 1 152 ? 44.353  -21.148 161.315 1.00 44.67  ? 171 LYS C O   1 
ATOM   6756  C CB  . LYS C 1 152 ? 47.539  -21.125 161.712 1.00 46.12  ? 171 LYS C CB  1 
ATOM   6757  C CG  . LYS C 1 152 ? 46.909  -21.199 163.105 1.00 48.36  ? 171 LYS C CG  1 
ATOM   6758  C CD  . LYS C 1 152 ? 47.957  -21.263 164.212 1.00 51.11  ? 171 LYS C CD  1 
ATOM   6759  C CE  . LYS C 1 152 ? 47.374  -20.854 165.604 1.00 53.68  ? 171 LYS C CE  1 
ATOM   6760  N NZ  . LYS C 1 152 ? 47.311  -21.959 166.627 1.00 56.23  ? 171 LYS C NZ  1 
ATOM   6761  N N   . ALA C 1 153 ? 45.255  -19.571 159.959 1.00 43.42  ? 172 ALA C N   1 
ATOM   6762  C CA  . ALA C 1 153 ? 44.083  -18.708 160.004 1.00 43.40  ? 172 ALA C CA  1 
ATOM   6763  C C   . ALA C 1 153 ? 42.966  -19.205 159.089 1.00 43.12  ? 172 ALA C C   1 
ATOM   6764  O O   . ALA C 1 153 ? 41.784  -19.125 159.459 1.00 43.73  ? 172 ALA C O   1 
ATOM   6765  C CB  . ALA C 1 153 ? 44.475  -17.276 159.628 1.00 43.02  ? 172 ALA C CB  1 
ATOM   6766  N N   . VAL C 1 154 ? 43.300  -19.738 157.907 1.00 42.16  ? 173 VAL C N   1 
ATOM   6767  C CA  . VAL C 1 154 ? 42.246  -20.064 156.938 1.00 42.74  ? 173 VAL C CA  1 
ATOM   6768  C C   . VAL C 1 154 ? 41.839  -21.535 156.966 1.00 43.86  ? 173 VAL C C   1 
ATOM   6769  O O   . VAL C 1 154 ? 40.666  -21.866 156.754 1.00 45.10  ? 173 VAL C O   1 
ATOM   6770  C CB  . VAL C 1 154 ? 42.648  -19.640 155.497 1.00 42.91  ? 173 VAL C CB  1 
ATOM   6771  C CG1 . VAL C 1 154 ? 43.319  -18.268 155.547 1.00 41.75  ? 173 VAL C CG1 1 
ATOM   6772  C CG2 . VAL C 1 154 ? 43.558  -20.692 154.857 1.00 43.56  ? 173 VAL C CG2 1 
ATOM   6773  N N   . VAL C 1 155 ? 42.795  -22.417 157.241 1.00 44.44  ? 174 VAL C N   1 
ATOM   6774  C CA  . VAL C 1 155 ? 42.542  -23.854 157.334 1.00 45.83  ? 174 VAL C CA  1 
ATOM   6775  C C   . VAL C 1 155 ? 42.055  -24.218 158.730 1.00 46.92  ? 174 VAL C C   1 
ATOM   6776  O O   . VAL C 1 155 ? 40.919  -24.670 158.902 1.00 48.66  ? 174 VAL C O   1 
ATOM   6777  C CB  . VAL C 1 155 ? 43.811  -24.644 156.966 1.00 45.87  ? 174 VAL C CB  1 
ATOM   6778  C CG1 . VAL C 1 155 ? 43.576  -26.142 157.077 1.00 47.33  ? 174 VAL C CG1 1 
ATOM   6779  C CG2 . VAL C 1 155 ? 44.279  -24.299 155.548 1.00 45.07  ? 174 VAL C CG2 1 
ATOM   6780  N N   . ASP C 1 156 ? 42.910  -24.050 159.741 1.00 46.92  ? 175 ASP C N   1 
ATOM   6781  C CA  . ASP C 1 156 ? 42.478  -24.350 161.102 1.00 48.56  ? 175 ASP C CA  1 
ATOM   6782  C C   . ASP C 1 156 ? 41.359  -23.422 161.548 1.00 48.32  ? 175 ASP C C   1 
ATOM   6783  O O   . ASP C 1 156 ? 40.529  -23.797 162.379 1.00 50.25  ? 175 ASP C O   1 
ATOM   6784  C CB  . ASP C 1 156 ? 43.640  -24.231 162.083 1.00 49.69  ? 175 ASP C CB  1 
ATOM   6785  C CG  . ASP C 1 156 ? 44.844  -24.998 161.632 1.00 51.45  ? 175 ASP C CG  1 
ATOM   6786  O OD1 . ASP C 1 156 ? 44.633  -26.010 160.911 1.00 52.76  ? 175 ASP C OD1 1 
ATOM   6787  O OD2 . ASP C 1 156 ? 45.995  -24.593 162.004 1.00 52.09  ? 175 ASP C OD2 1 
ATOM   6788  N N   . GLY C 1 157 ? 41.337  -22.193 161.049 1.00 44.97  ? 176 GLY C N   1 
ATOM   6789  C CA  . GLY C 1 157 ? 40.360  -21.227 161.474 1.00 44.97  ? 176 GLY C CA  1 
ATOM   6790  C C   . GLY C 1 157 ? 39.272  -20.992 160.440 1.00 45.12  ? 176 GLY C C   1 
ATOM   6791  O O   . GLY C 1 157 ? 39.174  -21.669 159.409 1.00 45.54  ? 176 GLY C O   1 
ATOM   6792  N N   . THR C 1 158 ? 38.469  -19.969 160.726 1.00 41.67  ? 177 THR C N   1 
ATOM   6793  C CA  . THR C 1 158 ? 37.187  -19.724 160.097 1.00 41.70  ? 177 THR C CA  1 
ATOM   6794  C C   . THR C 1 158 ? 37.284  -18.809 158.903 1.00 40.31  ? 177 THR C C   1 
ATOM   6795  O O   . THR C 1 158 ? 36.269  -18.548 158.260 1.00 40.38  ? 177 THR C O   1 
ATOM   6796  C CB  . THR C 1 158 ? 36.247  -19.139 161.132 1.00 42.93  ? 177 THR C CB  1 
ATOM   6797  O OG1 . THR C 1 158 ? 36.303  -19.966 162.286 1.00 44.44  ? 177 THR C OG1 1 
ATOM   6798  C CG2 . THR C 1 158 ? 34.854  -19.117 160.644 1.00 43.42  ? 177 THR C CG2 1 
ATOM   6799  N N   . CYS C 1 159 ? 38.476  -18.357 158.569 1.00 43.10  ? 178 CYS C N   1 
ATOM   6800  C CA  . CYS C 1 159 ? 38.619  -17.488 157.417 1.00 41.83  ? 178 CYS C CA  1 
ATOM   6801  C C   . CYS C 1 159 ? 38.563  -18.299 156.131 1.00 42.19  ? 178 CYS C C   1 
ATOM   6802  O O   . CYS C 1 159 ? 38.891  -19.483 156.108 1.00 42.98  ? 178 CYS C O   1 
ATOM   6803  C CB  . CYS C 1 159 ? 39.931  -16.720 157.505 1.00 40.86  ? 178 CYS C CB  1 
ATOM   6804  S SG  . CYS C 1 159 ? 39.793  -15.424 158.676 1.00 41.25  ? 178 CYS C SG  1 
ATOM   6805  N N   . ASP C 1 160 ? 38.181  -17.622 155.048 1.00 38.69  ? 179 ASP C N   1 
ATOM   6806  C CA  . ASP C 1 160 ? 38.011  -18.228 153.741 1.00 39.18  ? 179 ASP C CA  1 
ATOM   6807  C C   . ASP C 1 160 ? 39.154  -17.919 152.804 1.00 38.12  ? 179 ASP C C   1 
ATOM   6808  O O   . ASP C 1 160 ? 39.109  -18.324 151.634 1.00 39.01  ? 179 ASP C O   1 
ATOM   6809  C CB  . ASP C 1 160 ? 36.692  -17.777 153.146 1.00 40.84  ? 179 ASP C CB  1 
ATOM   6810  C CG  . ASP C 1 160 ? 35.522  -18.156 154.031 1.00 42.55  ? 179 ASP C CG  1 
ATOM   6811  O OD1 . ASP C 1 160 ? 35.162  -19.379 154.098 1.00 44.75  ? 179 ASP C OD1 1 
ATOM   6812  O OD2 . ASP C 1 160 ? 34.972  -17.254 154.693 1.00 42.64  ? 179 ASP C OD2 1 
ATOM   6813  N N   . GLY C 1 161 ? 40.189  -17.265 153.285 1.00 39.61  ? 180 GLY C N   1 
ATOM   6814  C CA  . GLY C 1 161 ? 41.313  -16.917 152.441 1.00 38.66  ? 180 GLY C CA  1 
ATOM   6815  C C   . GLY C 1 161 ? 42.132  -15.815 153.074 1.00 37.64  ? 180 GLY C C   1 
ATOM   6816  O O   . GLY C 1 161 ? 41.866  -15.344 154.179 1.00 37.83  ? 180 GLY C O   1 
ATOM   6817  N N   . VAL C 1 162 ? 43.126  -15.376 152.314 1.00 39.52  ? 181 VAL C N   1 
ATOM   6818  C CA  . VAL C 1 162 ? 44.158  -14.496 152.822 1.00 39.20  ? 181 VAL C CA  1 
ATOM   6819  C C   . VAL C 1 162 ? 44.331  -13.293 151.898 1.00 39.25  ? 181 VAL C C   1 
ATOM   6820  O O   . VAL C 1 162 ? 44.253  -13.415 150.668 1.00 39.74  ? 181 VAL C O   1 
ATOM   6821  C CB  . VAL C 1 162 ? 45.482  -15.286 152.991 1.00 39.05  ? 181 VAL C CB  1 
ATOM   6822  C CG1 . VAL C 1 162 ? 45.951  -15.786 151.604 1.00 39.39  ? 181 VAL C CG1 1 
ATOM   6823  C CG2 . VAL C 1 162 ? 46.534  -14.429 153.734 1.00 39.53  ? 181 VAL C CG2 1 
ATOM   6824  N N   . PHE C 1 163 ? 44.560  -12.121 152.514 1.00 39.43  ? 182 PHE C N   1 
ATOM   6825  C CA  . PHE C 1 163 ? 44.873  -10.886 151.812 1.00 39.75  ? 182 PHE C CA  1 
ATOM   6826  C C   . PHE C 1 163 ? 46.374  -10.660 151.895 1.00 40.07  ? 182 PHE C C   1 
ATOM   6827  O O   . PHE C 1 163 ? 46.902  -10.387 152.971 1.00 40.73  ? 182 PHE C O   1 
ATOM   6828  C CB  . PHE C 1 163 ? 44.116  -9.711  152.427 1.00 40.33  ? 182 PHE C CB  1 
ATOM   6829  C CG  . PHE C 1 163 ? 44.221  -8.455  151.631 1.00 41.11  ? 182 PHE C CG  1 
ATOM   6830  C CD1 . PHE C 1 163 ? 45.297  -7.604  151.812 1.00 41.68  ? 182 PHE C CD1 1 
ATOM   6831  C CD2 . PHE C 1 163 ? 43.276  -8.144  150.668 1.00 41.79  ? 182 PHE C CD2 1 
ATOM   6832  C CE1 . PHE C 1 163 ? 45.401  -6.442  151.064 1.00 42.49  ? 182 PHE C CE1 1 
ATOM   6833  C CE2 . PHE C 1 163 ? 43.385  -6.989  149.920 1.00 42.88  ? 182 PHE C CE2 1 
ATOM   6834  C CZ  . PHE C 1 163 ? 44.448  -6.139  150.111 1.00 43.03  ? 182 PHE C CZ  1 
ATOM   6835  N N   . MET C 1 164 ? 47.089  -10.813 150.777 1.00 40.74  ? 183 MET C N   1 
ATOM   6836  C CA  . MET C 1 164 ? 48.562  -10.628 150.717 1.00 41.44  ? 183 MET C CA  1 
ATOM   6837  C C   . MET C 1 164 ? 48.843  -9.195  150.250 1.00 41.92  ? 183 MET C C   1 
ATOM   6838  O O   . MET C 1 164 ? 48.761  -8.961  149.033 1.00 42.69  ? 183 MET C O   1 
ATOM   6839  C CB  . MET C 1 164 ? 49.177  -11.648 149.753 1.00 41.26  ? 183 MET C CB  1 
ATOM   6840  C CG  . MET C 1 164 ? 48.921  -13.091 150.146 1.00 41.29  ? 183 MET C CG  1 
ATOM   6841  S SD  . MET C 1 164 ? 49.600  -14.289 148.980 1.00 42.27  ? 183 MET C SD  1 
ATOM   6842  C CE  . MET C 1 164 ? 51.368  -14.000 149.136 1.00 42.78  ? 183 MET C CE  1 
ATOM   6843  N N   . ASP C 1 165 ? 49.203  -8.286  151.159 1.00 42.64  ? 184 ASP C N   1 
ATOM   6844  C CA  . ASP C 1 165 ? 49.365  -6.847  150.808 1.00 43.74  ? 184 ASP C CA  1 
ATOM   6845  C C   . ASP C 1 165 ? 50.825  -6.434  150.652 1.00 45.30  ? 184 ASP C C   1 
ATOM   6846  O O   . ASP C 1 165 ? 51.672  -7.108  151.264 1.00 45.83  ? 184 ASP C O   1 
ATOM   6847  C CB  . ASP C 1 165 ? 48.784  -5.951  151.889 1.00 44.28  ? 184 ASP C CB  1 
ATOM   6848  C CG  . ASP C 1 165 ? 48.704  -4.465  151.563 1.00 45.25  ? 184 ASP C CG  1 
ATOM   6849  O OD1 . ASP C 1 165 ? 49.063  -4.079  150.440 1.00 46.18  ? 184 ASP C OD1 1 
ATOM   6850  O OD2 . ASP C 1 165 ? 48.294  -3.694  152.443 1.00 45.85  ? 184 ASP C OD2 1 
ATOM   6851  N N   . ALA C 1 166 ? 51.108  -5.408  149.842 1.00 42.79  ? 185 ALA C N   1 
ATOM   6852  C CA  . ALA C 1 166 ? 52.451  -4.790  149.710 1.00 44.69  ? 185 ALA C CA  1 
ATOM   6853  C C   . ALA C 1 166 ? 53.249  -5.387  148.554 1.00 45.47  ? 185 ALA C C   1 
ATOM   6854  O O   . ALA C 1 166 ? 54.488  -5.335  148.654 1.00 47.53  ? 185 ALA C O   1 
ATOM   6855  C CB  . ALA C 1 166 ? 53.231  -4.877  151.012 1.00 45.65  ? 185 ALA C CB  1 
ATOM   6856  N N   . PHE C 1 167 ? 52.619  -5.908  147.495 1.00 46.62  ? 186 PHE C N   1 
ATOM   6857  C CA  . PHE C 1 167 ? 53.429  -6.349  146.369 1.00 47.74  ? 186 PHE C CA  1 
ATOM   6858  C C   . PHE C 1 167 ? 54.177  -5.192  145.711 1.00 50.28  ? 186 PHE C C   1 
ATOM   6859  O O   . PHE C 1 167 ? 55.338  -5.388  145.312 1.00 52.33  ? 186 PHE C O   1 
ATOM   6860  C CB  . PHE C 1 167 ? 52.571  -7.069  145.318 1.00 47.15  ? 186 PHE C CB  1 
ATOM   6861  C CG  . PHE C 1 167 ? 52.111  -8.474  145.693 1.00 45.49  ? 186 PHE C CG  1 
ATOM   6862  C CD1 . PHE C 1 167 ? 51.969  -8.884  147.009 1.00 44.33  ? 186 PHE C CD1 1 
ATOM   6863  C CD2 . PHE C 1 167 ? 51.761  -9.358  144.694 1.00 45.87  ? 186 PHE C CD2 1 
ATOM   6864  C CE1 . PHE C 1 167 ? 51.496  -10.180 147.327 1.00 42.92  ? 186 PHE C CE1 1 
ATOM   6865  C CE2 . PHE C 1 167 ? 51.290  -10.651 144.993 1.00 44.64  ? 186 PHE C CE2 1 
ATOM   6866  C CZ  . PHE C 1 167 ? 51.158  -11.058 146.315 1.00 43.19  ? 186 PHE C CZ  1 
ATOM   6867  N N   . PRO C 1 168 ? 53.594  -4.002  145.541 1.00 47.48  ? 187 PRO C N   1 
ATOM   6868  C CA  . PRO C 1 168 ? 54.355  -2.931  144.875 1.00 50.10  ? 187 PRO C CA  1 
ATOM   6869  C C   . PRO C 1 168 ? 55.590  -2.533  145.650 1.00 52.08  ? 187 PRO C C   1 
ATOM   6870  O O   . PRO C 1 168 ? 56.636  -2.242  145.068 1.00 54.91  ? 187 PRO C O   1 
ATOM   6871  C CB  . PRO C 1 168 ? 53.337  -1.782  144.768 1.00 50.08  ? 187 PRO C CB  1 
ATOM   6872  C CG  . PRO C 1 168 ? 52.011  -2.432  144.829 1.00 48.10  ? 187 PRO C CG  1 
ATOM   6873  C CD  . PRO C 1 168 ? 52.193  -3.617  145.766 1.00 46.51  ? 187 PRO C CD  1 
ATOM   6874  N N   . GLN C 1 169 ? 55.500  -2.525  146.970 1.00 51.90  ? 188 GLN C N   1 
ATOM   6875  C CA  . GLN C 1 169 ? 56.691  -2.261  147.772 1.00 53.47  ? 188 GLN C CA  1 
ATOM   6876  C C   . GLN C 1 169 ? 57.772  -3.328  147.576 1.00 54.59  ? 188 GLN C C   1 
ATOM   6877  O O   . GLN C 1 169 ? 58.958  -2.994  147.505 1.00 57.08  ? 188 GLN C O   1 
ATOM   6878  C CB  . GLN C 1 169 ? 56.266  -2.126  149.231 1.00 52.19  ? 188 GLN C CB  1 
ATOM   6879  C CG  . GLN C 1 169 ? 55.098  -1.157  149.377 1.00 51.67  ? 188 GLN C CG  1 
ATOM   6880  C CD  . GLN C 1 169 ? 54.628  -0.970  150.815 1.00 51.12  ? 188 GLN C CD  1 
ATOM   6881  O OE1 . GLN C 1 169 ? 55.379  -0.521  151.704 1.00 52.92  ? 188 GLN C OE1 1 
ATOM   6882  N NE2 . GLN C 1 169 ? 53.372  -1.298  151.047 1.00 49.50  ? 188 GLN C NE2 1 
ATOM   6883  N N   . ILE C 1 170 ? 57.398  -4.610  147.459 1.00 53.01  ? 189 ILE C N   1 
ATOM   6884  C CA  . ILE C 1 170 ? 58.417  -5.626  147.189 1.00 54.12  ? 189 ILE C CA  1 
ATOM   6885  C C   . ILE C 1 170 ? 59.105  -5.352  145.855 1.00 56.40  ? 189 ILE C C   1 
ATOM   6886  O O   . ILE C 1 170 ? 60.335  -5.477  145.728 1.00 58.74  ? 189 ILE C O   1 
ATOM   6887  C CB  . ILE C 1 170 ? 57.805  -7.039  147.206 1.00 51.76  ? 189 ILE C CB  1 
ATOM   6888  C CG1 . ILE C 1 170 ? 57.262  -7.395  148.592 1.00 50.24  ? 189 ILE C CG1 1 
ATOM   6889  C CG2 . ILE C 1 170 ? 58.826  -8.112  146.792 1.00 53.21  ? 189 ILE C CG2 1 
ATOM   6890  C CD1 . ILE C 1 170 ? 56.249  -8.502  148.596 1.00 47.85  ? 189 ILE C CD1 1 
ATOM   6891  N N   . ALA C 1 171 ? 58.321  -4.984  144.839 1.00 54.77  ? 190 ALA C N   1 
ATOM   6892  C CA  . ALA C 1 171 ? 58.801  -4.796  143.472 1.00 56.96  ? 190 ALA C CA  1 
ATOM   6893  C C   . ALA C 1 171 ? 59.497  -3.455  143.234 1.00 59.05  ? 190 ALA C C   1 
ATOM   6894  O O   . ALA C 1 171 ? 60.094  -3.272  142.164 1.00 61.10  ? 190 ALA C O   1 
ATOM   6895  C CB  . ALA C 1 171 ? 57.625  -4.915  142.494 1.00 55.50  ? 190 ALA C CB  1 
ATOM   6896  N N   . SER C 1 172 ? 59.438  -2.522  144.189 1.00 57.92  ? 191 SER C N   1 
ATOM   6897  C CA  . SER C 1 172 ? 60.014  -1.205  143.977 1.00 59.85  ? 191 SER C CA  1 
ATOM   6898  C C   . SER C 1 172 ? 61.426  -1.327  143.431 1.00 63.00  ? 191 SER C C   1 
ATOM   6899  O O   . SER C 1 172 ? 62.225  -2.136  143.906 1.00 63.33  ? 191 SER C O   1 
ATOM   6900  C CB  . SER C 1 172 ? 60.043  -0.411  145.278 1.00 60.06  ? 191 SER C CB  1 
ATOM   6901  O OG  . SER C 1 172 ? 60.739  0.808   145.088 1.00 62.68  ? 191 SER C OG  1 
ATOM   6902  N N   . GLN C 1 173 ? 61.734  -0.505  142.422 1.00 62.29  ? 192 GLN C N   1 
ATOM   6903  C CA  . GLN C 1 173 ? 63.081  -0.520  141.866 1.00 65.77  ? 192 GLN C CA  1 
ATOM   6904  C C   . GLN C 1 173 ? 64.086  0.072   142.833 1.00 67.74  ? 192 GLN C C   1 
ATOM   6905  O O   . GLN C 1 173 ? 65.274  -0.247  142.745 1.00 70.48  ? 192 GLN C O   1 
ATOM   6906  C CB  . GLN C 1 173 ? 63.140  0.227   140.541 1.00 67.45  ? 192 GLN C CB  1 
ATOM   6907  C CG  . GLN C 1 173 ? 64.094  -0.420  139.539 1.00 69.06  ? 192 GLN C CG  1 
ATOM   6908  C CD  . GLN C 1 173 ? 63.656  -1.829  139.126 1.00 68.96  ? 192 GLN C CD  1 
ATOM   6909  O OE1 . GLN C 1 173 ? 62.641  -2.342  139.610 1.00 68.24  ? 192 GLN C OE1 1 
ATOM   6910  N NE2 . GLN C 1 173 ? 64.415  -2.453  138.221 1.00 70.13  ? 192 GLN C NE2 1 
ATOM   6911  N N   . ALA C 1 174 ? 63.635  0.900   143.772 1.00 66.56  ? 193 ALA C N   1 
ATOM   6912  C CA  . ALA C 1 174 ? 64.554  1.440   144.759 1.00 67.94  ? 193 ALA C CA  1 
ATOM   6913  C C   . ALA C 1 174 ? 65.186  0.356   145.618 1.00 68.01  ? 193 ALA C C   1 
ATOM   6914  O O   . ALA C 1 174 ? 66.262  0.573   146.201 1.00 70.36  ? 193 ALA C O   1 
ATOM   6915  C CB  . ALA C 1 174 ? 63.842  2.417   145.685 1.00 66.76  ? 193 ALA C CB  1 
ATOM   6916  N N   . ASN C 1 175 ? 64.530  -0.791  145.742 1.00 67.92  ? 194 ASN C N   1 
ATOM   6917  C CA  . ASN C 1 175 ? 65.047  -1.801  146.647 1.00 68.25  ? 194 ASN C CA  1 
ATOM   6918  C C   . ASN C 1 175 ? 66.386  -2.342  146.184 1.00 71.69  ? 194 ASN C C   1 
ATOM   6919  O O   . ASN C 1 175 ? 67.153  -2.821  147.021 1.00 73.68  ? 194 ASN C O   1 
ATOM   6920  C CB  . ASN C 1 175 ? 64.000  -2.893  146.814 1.00 65.11  ? 194 ASN C CB  1 
ATOM   6921  C CG  . ASN C 1 175 ? 62.806  -2.408  147.621 1.00 62.43  ? 194 ASN C CG  1 
ATOM   6922  O OD1 . ASN C 1 175 ? 62.933  -1.510  148.454 1.00 62.87  ? 194 ASN C OD1 1 
ATOM   6923  N ND2 . ASN C 1 175 ? 61.643  -3.011  147.389 1.00 59.82  ? 194 ASN C ND2 1 
ATOM   6924  N N   . ARG C 1 176 ? 66.702  -2.234  144.888 1.00 68.28  ? 195 ARG C N   1 
ATOM   6925  C CA  . ARG C 1 176 ? 68.023  -2.638  144.411 1.00 72.00  ? 195 ARG C CA  1 
ATOM   6926  C C   . ARG C 1 176 ? 69.112  -1.961  145.228 1.00 75.52  ? 195 ARG C C   1 
ATOM   6927  O O   . ARG C 1 176 ? 70.033  -2.620  145.726 1.00 78.69  ? 195 ARG C O   1 
ATOM   6928  C CB  . ARG C 1 176 ? 68.188  -2.300  142.925 1.00 73.35  ? 195 ARG C CB  1 
ATOM   6929  C CG  . ARG C 1 176 ? 67.331  -3.148  142.028 1.00 70.80  ? 195 ARG C CG  1 
ATOM   6930  C CD  . ARG C 1 176 ? 67.525  -2.886  140.542 1.00 72.51  ? 195 ARG C CD  1 
ATOM   6931  N NE  . ARG C 1 176 ? 66.579  -3.691  139.767 1.00 70.13  ? 195 ARG C NE  1 
ATOM   6932  C CZ  . ARG C 1 176 ? 66.761  -4.961  139.420 1.00 69.67  ? 195 ARG C CZ  1 
ATOM   6933  N NH1 . ARG C 1 176 ? 67.901  -5.591  139.668 1.00 71.38  ? 195 ARG C NH1 1 
ATOM   6934  N NH2 . ARG C 1 176 ? 65.773  -5.611  138.808 1.00 67.17  ? 195 ARG C NH2 1 
ATOM   6935  N N   . LYS C 1 177 ? 69.000  -0.634  145.394 1.00 73.68  ? 196 LYS C N   1 
ATOM   6936  C CA  . LYS C 1 177 ? 70.028  0.125   146.100 1.00 76.04  ? 196 LYS C CA  1 
ATOM   6937  C C   . LYS C 1 177 ? 70.240  -0.417  147.503 1.00 75.18  ? 196 LYS C C   1 
ATOM   6938  O O   . LYS C 1 177 ? 71.368  -0.400  148.007 1.00 77.11  ? 196 LYS C O   1 
ATOM   6939  C CB  . LYS C 1 177 ? 69.657  1.607   146.155 1.00 76.22  ? 196 LYS C CB  1 
ATOM   6940  N N   . LEU C 1 178 ? 69.183  -0.933  148.136 1.00 75.68  ? 197 LEU C N   1 
ATOM   6941  C CA  . LEU C 1 178 ? 69.324  -1.476  149.481 1.00 75.45  ? 197 LEU C CA  1 
ATOM   6942  C C   . LEU C 1 178 ? 69.957  -2.860  149.476 1.00 76.97  ? 197 LEU C C   1 
ATOM   6943  O O   . LEU C 1 178 ? 70.792  -3.167  150.338 1.00 78.16  ? 197 LEU C O   1 
ATOM   6944  C CB  . LEU C 1 178 ? 67.953  -1.537  150.167 1.00 72.90  ? 197 LEU C CB  1 
ATOM   6945  C CG  . LEU C 1 178 ? 67.536  -0.269  150.925 1.00 72.23  ? 197 LEU C CG  1 
ATOM   6946  C CD1 . LEU C 1 178 ? 66.712  0.601   150.014 1.00 72.29  ? 197 LEU C CD1 1 
ATOM   6947  C CD2 . LEU C 1 178 ? 66.772  -0.584  152.205 1.00 69.96  ? 197 LEU C CD2 1 
ATOM   6948  N N   . TRP C 1 179 ? 69.560  -3.701  148.514 1.00 77.03  ? 198 TRP C N   1 
ATOM   6949  C CA  . TRP C 1 179 ? 69.820  -5.136  148.555 1.00 78.10  ? 198 TRP C CA  1 
ATOM   6950  C C   . TRP C 1 179 ? 70.865  -5.612  147.556 1.00 80.35  ? 198 TRP C C   1 
ATOM   6951  O O   . TRP C 1 179 ? 71.402  -6.721  147.714 1.00 80.48  ? 198 TRP C O   1 
ATOM   6952  C CB  . TRP C 1 179 ? 68.532  -5.927  148.262 1.00 73.82  ? 198 TRP C CB  1 
ATOM   6953  C CG  . TRP C 1 179 ? 67.365  -5.644  149.141 1.00 70.52  ? 198 TRP C CG  1 
ATOM   6954  C CD1 . TRP C 1 179 ? 67.384  -5.201  150.424 1.00 70.71  ? 198 TRP C CD1 1 
ATOM   6955  C CD2 . TRP C 1 179 ? 66.000  -5.817  148.796 1.00 66.26  ? 198 TRP C CD2 1 
ATOM   6956  N NE1 . TRP C 1 179 ? 66.106  -5.082  150.904 1.00 67.07  ? 198 TRP C NE1 1 
ATOM   6957  C CE2 . TRP C 1 179 ? 65.235  -5.445  149.915 1.00 64.54  ? 198 TRP C CE2 1 
ATOM   6958  C CE3 . TRP C 1 179 ? 65.343  -6.261  147.644 1.00 63.95  ? 198 TRP C CE3 1 
ATOM   6959  C CZ2 . TRP C 1 179 ? 63.841  -5.499  149.918 1.00 60.67  ? 198 TRP C CZ2 1 
ATOM   6960  C CZ3 . TRP C 1 179 ? 63.962  -6.315  147.646 1.00 60.41  ? 198 TRP C CZ3 1 
ATOM   6961  C CH2 . TRP C 1 179 ? 63.224  -5.934  148.778 1.00 58.90  ? 198 TRP C CH2 1 
ATOM   6962  N N   . GLY C 1 180 ? 71.142  -4.822  146.531 1.00 77.50  ? 199 GLY C N   1 
ATOM   6963  C CA  . GLY C 1 180 ? 71.889  -5.306  145.397 1.00 78.62  ? 199 GLY C CA  1 
ATOM   6964  C C   . GLY C 1 180 ? 70.988  -5.986  144.379 1.00 75.76  ? 199 GLY C C   1 
ATOM   6965  O O   . GLY C 1 180 ? 69.842  -6.356  144.649 1.00 72.43  ? 199 GLY C O   1 
ATOM   6966  N N   . ASP C 1 181 ? 71.534  -6.161  143.189 1.00 73.47  ? 200 ASP C N   1 
ATOM   6967  C CA  . ASP C 1 181 ? 70.743  -6.706  142.092 1.00 73.33  ? 200 ASP C CA  1 
ATOM   6968  C C   . ASP C 1 181 ? 70.546  -8.214  142.225 1.00 73.25  ? 200 ASP C C   1 
ATOM   6969  O O   . ASP C 1 181 ? 69.452  -8.714  141.926 1.00 72.30  ? 200 ASP C O   1 
ATOM   6970  C CB  . ASP C 1 181 ? 71.418  -6.321  140.771 1.00 74.70  ? 200 ASP C CB  1 
ATOM   6971  C CG  . ASP C 1 181 ? 71.503  -4.806  140.583 1.00 75.55  ? 200 ASP C CG  1 
ATOM   6972  O OD1 . ASP C 1 181 ? 70.547  -4.092  140.981 1.00 73.25  ? 200 ASP C OD1 1 
ATOM   6973  O OD2 . ASP C 1 181 ? 72.534  -4.331  140.057 1.00 79.05  ? 200 ASP C OD2 1 
ATOM   6974  N N   . GLU C 1 182 ? 71.565  -8.953  142.692 1.00 71.03  ? 201 GLU C N   1 
ATOM   6975  C CA  . GLU C 1 182 ? 71.395  -10.393 142.887 1.00 70.92  ? 201 GLU C CA  1 
ATOM   6976  C C   . GLU C 1 182 ? 70.359  -10.669 143.972 1.00 68.72  ? 201 GLU C C   1 
ATOM   6977  O O   . GLU C 1 182 ? 69.389  -11.401 143.746 1.00 67.32  ? 201 GLU C O   1 
ATOM   6978  C CB  . GLU C 1 182 ? 72.726  -11.057 143.230 1.00 72.89  ? 201 GLU C CB  1 
ATOM   6979  N N   . LYS C 1 183 ? 70.518  -10.056 145.147 1.00 73.32  ? 202 LYS C N   1 
ATOM   6980  C CA  . LYS C 1 183 ? 69.536  -10.262 146.209 1.00 70.49  ? 202 LYS C CA  1 
ATOM   6981  C C   . LYS C 1 183 ? 68.145  -9.836  145.748 1.00 68.30  ? 202 LYS C C   1 
ATOM   6982  O O   . LYS C 1 183 ? 67.175  -10.576 145.926 1.00 65.51  ? 202 LYS C O   1 
ATOM   6983  C CB  . LYS C 1 183 ? 69.952  -9.518  147.480 1.00 69.74  ? 202 LYS C CB  1 
ATOM   6984  C CG  . LYS C 1 183 ? 68.971  -9.687  148.652 1.00 66.39  ? 202 LYS C CG  1 
ATOM   6985  C CD  . LYS C 1 183 ? 68.843  -11.160 149.090 1.00 65.84  ? 202 LYS C CD  1 
ATOM   6986  C CE  . LYS C 1 183 ? 68.648  -11.325 150.608 1.00 64.08  ? 202 LYS C CE  1 
ATOM   6987  N NZ  . LYS C 1 183 ? 69.601  -12.331 151.233 1.00 64.75  ? 202 LYS C NZ  1 
ATOM   6988  N N   . PHE C 1 184 ? 68.041  -8.654  145.106 1.00 69.14  ? 203 PHE C N   1 
ATOM   6989  C CA  . PHE C 1 184 ? 66.752  -8.134  144.636 1.00 67.64  ? 203 PHE C CA  1 
ATOM   6990  C C   . PHE C 1 184 ? 66.041  -9.097  143.697 1.00 68.02  ? 203 PHE C C   1 
ATOM   6991  O O   . PHE C 1 184 ? 64.823  -9.286  143.793 1.00 65.29  ? 203 PHE C O   1 
ATOM   6992  C CB  . PHE C 1 184 ? 66.938  -6.811  143.896 1.00 69.32  ? 203 PHE C CB  1 
ATOM   6993  C CG  . PHE C 1 184 ? 65.668  -6.275  143.281 1.00 67.46  ? 203 PHE C CG  1 
ATOM   6994  C CD1 . PHE C 1 184 ? 64.871  -5.402  143.990 1.00 65.15  ? 203 PHE C CD1 1 
ATOM   6995  C CD2 . PHE C 1 184 ? 65.278  -6.639  142.007 1.00 68.59  ? 203 PHE C CD2 1 
ATOM   6996  C CE1 . PHE C 1 184 ? 63.707  -4.904  143.441 1.00 63.93  ? 203 PHE C CE1 1 
ATOM   6997  C CE2 . PHE C 1 184 ? 64.118  -6.145  141.460 1.00 67.01  ? 203 PHE C CE2 1 
ATOM   6998  C CZ  . PHE C 1 184 ? 63.331  -5.280  142.173 1.00 64.71  ? 203 PHE C CZ  1 
ATOM   6999  N N   . GLU C 1 185 ? 66.760  -9.616  142.697 1.00 67.14  ? 204 GLU C N   1 
ATOM   7000  C CA  . GLU C 1 185 ? 66.153  -10.597 141.806 1.00 66.61  ? 204 GLU C CA  1 
ATOM   7001  C C   . GLU C 1 185 ? 65.718  -11.833 142.586 1.00 63.17  ? 204 GLU C C   1 
ATOM   7002  O O   . GLU C 1 185 ? 64.715  -12.467 142.239 1.00 61.63  ? 204 GLU C O   1 
ATOM   7003  C CB  . GLU C 1 185 ? 67.128  -10.947 140.686 1.00 68.15  ? 204 GLU C CB  1 
ATOM   7004  N N   . ALA C 1 186 ? 66.412  -12.152 143.683 1.00 65.22  ? 205 ALA C N   1 
ATOM   7005  C CA  . ALA C 1 186 ? 66.052  -13.327 144.469 1.00 62.40  ? 205 ALA C CA  1 
ATOM   7006  C C   . ALA C 1 186 ? 64.783  -13.098 145.276 1.00 59.20  ? 205 ALA C C   1 
ATOM   7007  O O   . ALA C 1 186 ? 64.008  -14.030 145.511 1.00 57.29  ? 205 ALA C O   1 
ATOM   7008  C CB  . ALA C 1 186 ? 67.184  -13.703 145.420 1.00 62.42  ? 205 ALA C CB  1 
ATOM   7009  N N   . ILE C 1 187 ? 64.592  -11.876 145.783 1.00 63.99  ? 206 ILE C N   1 
ATOM   7010  C CA  . ILE C 1 187 ? 63.396  -11.571 146.567 1.00 60.66  ? 206 ILE C CA  1 
ATOM   7011  C C   . ILE C 1 187 ? 62.163  -11.558 145.665 1.00 60.34  ? 206 ILE C C   1 
ATOM   7012  O O   . ILE C 1 187 ? 61.059  -11.917 146.099 1.00 57.83  ? 206 ILE C O   1 
ATOM   7013  C CB  . ILE C 1 187 ? 63.603  -10.240 147.328 1.00 60.53  ? 206 ILE C CB  1 
ATOM   7014  C CG1 . ILE C 1 187 ? 64.734  -10.424 148.359 1.00 60.41  ? 206 ILE C CG1 1 
ATOM   7015  C CG2 . ILE C 1 187 ? 62.288  -9.735  147.969 1.00 57.53  ? 206 ILE C CG2 1 
ATOM   7016  C CD1 . ILE C 1 187 ? 64.694  -9.468  149.605 1.00 60.06  ? 206 ILE C CD1 1 
ATOM   7017  N N   . GLN C 1 188 ? 62.320  -11.176 144.398 1.00 60.56  ? 207 GLN C N   1 
ATOM   7018  C CA  . GLN C 1 188 ? 61.171  -11.212 143.501 1.00 60.56  ? 207 GLN C CA  1 
ATOM   7019  C C   . GLN C 1 188 ? 60.765  -12.655 143.215 1.00 60.49  ? 207 GLN C C   1 
ATOM   7020  O O   . GLN C 1 188 ? 59.576  -12.983 143.215 1.00 58.83  ? 207 GLN C O   1 
ATOM   7021  C CB  . GLN C 1 188 ? 61.467  -10.465 142.202 1.00 63.72  ? 207 GLN C CB  1 
ATOM   7022  C CG  . GLN C 1 188 ? 61.857  -9.007  142.377 1.00 63.99  ? 207 GLN C CG  1 
ATOM   7023  C CD  . GLN C 1 188 ? 60.939  -8.224  143.315 1.00 60.91  ? 207 GLN C CD  1 
ATOM   7024  O OE1 . GLN C 1 188 ? 59.709  -8.253  143.184 1.00 59.23  ? 207 GLN C OE1 1 
ATOM   7025  N NE2 . GLN C 1 188 ? 61.545  -7.491  144.250 1.00 60.51  ? 207 GLN C NE2 1 
ATOM   7026  N N   . GLN C 1 189 ? 61.729  -13.538 142.973 1.00 59.65  ? 208 GLN C N   1 
ATOM   7027  C CA  . GLN C 1 189 ? 61.369  -14.945 142.833 1.00 58.84  ? 208 GLN C CA  1 
ATOM   7028  C C   . GLN C 1 189 ? 60.772  -15.491 144.127 1.00 55.49  ? 208 GLN C C   1 
ATOM   7029  O O   . GLN C 1 189 ? 59.898  -16.368 144.083 1.00 54.63  ? 208 GLN C O   1 
ATOM   7030  C CB  . GLN C 1 189 ? 62.589  -15.762 142.405 1.00 60.73  ? 208 GLN C CB  1 
ATOM   7031  C CG  . GLN C 1 189 ? 62.373  -17.294 142.272 1.00 60.51  ? 208 GLN C CG  1 
ATOM   7032  C CD  . GLN C 1 189 ? 61.325  -17.726 141.208 1.00 61.61  ? 208 GLN C CD  1 
ATOM   7033  O OE1 . GLN C 1 189 ? 61.285  -17.216 140.073 1.00 64.34  ? 208 GLN C OE1 1 
ATOM   7034  N NE2 . GLN C 1 189 ? 60.490  -18.695 141.580 1.00 60.17  ? 208 GLN C NE2 1 
ATOM   7035  N N   . GLY C 1 190 ? 61.218  -14.987 145.285 1.00 57.66  ? 209 GLY C N   1 
ATOM   7036  C CA  . GLY C 1 190 ? 60.708  -15.443 146.564 1.00 54.64  ? 209 GLY C CA  1 
ATOM   7037  C C   . GLY C 1 190 ? 59.261  -15.105 146.791 1.00 52.26  ? 209 GLY C C   1 
ATOM   7038  O O   . GLY C 1 190 ? 58.602  -15.784 147.594 1.00 50.38  ? 209 GLY C O   1 
ATOM   7039  N N   . LEU C 1 191 ? 58.775  -14.060 146.115 1.00 53.42  ? 210 LEU C N   1 
ATOM   7040  C CA  . LEU C 1 191 ? 57.367  -13.693 146.137 1.00 51.25  ? 210 LEU C CA  1 
ATOM   7041  C C   . LEU C 1 191 ? 56.552  -14.639 145.273 1.00 51.78  ? 210 LEU C C   1 
ATOM   7042  O O   . LEU C 1 191 ? 55.450  -15.057 145.656 1.00 49.41  ? 210 LEU C O   1 
ATOM   7043  C CB  . LEU C 1 191 ? 57.206  -12.258 145.625 1.00 52.28  ? 210 LEU C CB  1 
ATOM   7044  C CG  . LEU C 1 191 ? 55.790  -11.748 145.390 1.00 50.18  ? 210 LEU C CG  1 
ATOM   7045  C CD1 . LEU C 1 191 ? 55.024  -11.698 146.686 1.00 46.69  ? 210 LEU C CD1 1 
ATOM   7046  C CD2 . LEU C 1 191 ? 55.852  -10.368 144.755 1.00 51.54  ? 210 LEU C CD2 1 
ATOM   7047  N N   . GLN C 1 192 ? 57.063  -14.941 144.080 1.00 53.81  ? 211 GLN C N   1 
ATOM   7048  C CA  . GLN C 1 192 ? 56.466  -15.982 143.259 1.00 54.69  ? 211 GLN C CA  1 
ATOM   7049  C C   . GLN C 1 192 ? 56.332  -17.251 144.071 1.00 53.01  ? 211 GLN C C   1 
ATOM   7050  O O   . GLN C 1 192 ? 55.298  -17.929 144.024 1.00 51.79  ? 211 GLN C O   1 
ATOM   7051  C CB  . GLN C 1 192 ? 57.324  -16.188 142.016 1.00 58.00  ? 211 GLN C CB  1 
ATOM   7052  C CG  . GLN C 1 192 ? 57.087  -17.492 141.255 1.00 59.56  ? 211 GLN C CG  1 
ATOM   7053  C CD  . GLN C 1 192 ? 55.707  -17.577 140.630 1.00 60.30  ? 211 GLN C CD  1 
ATOM   7054  O OE1 . GLN C 1 192 ? 55.067  -18.662 140.630 1.00 59.41  ? 211 GLN C OE1 1 
ATOM   7055  N NE2 . GLN C 1 192 ? 55.225  -16.438 140.089 1.00 61.61  ? 211 GLN C NE2 1 
ATOM   7056  N N   . ASP C 1 193 ? 57.365  -17.554 144.859 1.00 54.18  ? 212 ASP C N   1 
ATOM   7057  C CA  . ASP C 1 193 ? 57.414  -18.800 145.619 1.00 52.83  ? 212 ASP C CA  1 
ATOM   7058  C C   . ASP C 1 193 ? 56.442  -18.769 146.781 1.00 49.26  ? 212 ASP C C   1 
ATOM   7059  O O   . ASP C 1 193 ? 55.664  -19.706 146.967 1.00 48.50  ? 212 ASP C O   1 
ATOM   7060  C CB  . ASP C 1 193 ? 58.836  -19.045 146.109 1.00 54.01  ? 212 ASP C CB  1 
ATOM   7061  C CG  . ASP C 1 193 ? 59.775  -19.404 144.985 1.00 57.79  ? 212 ASP C CG  1 
ATOM   7062  O OD1 . ASP C 1 193 ? 59.259  -19.794 143.909 1.00 59.41  ? 212 ASP C OD1 1 
ATOM   7063  O OD2 . ASP C 1 193 ? 61.012  -19.292 145.180 1.00 59.83  ? 212 ASP C OD2 1 
ATOM   7064  N N   . ILE C 1 194 ? 56.423  -17.674 147.535 1.00 51.54  ? 213 ILE C N   1 
ATOM   7065  C CA  . ILE C 1 194 ? 55.540  -17.625 148.687 1.00 48.70  ? 213 ILE C CA  1 
ATOM   7066  C C   . ILE C 1 194 ? 54.095  -17.716 148.266 1.00 47.31  ? 213 ILE C C   1 
ATOM   7067  O O   . ILE C 1 194 ? 53.252  -18.194 149.023 1.00 45.34  ? 213 ILE C O   1 
ATOM   7068  C CB  . ILE C 1 194 ? 55.787  -16.350 149.490 1.00 47.69  ? 213 ILE C CB  1 
ATOM   7069  C CG1 . ILE C 1 194 ? 55.521  -16.631 150.958 1.00 45.33  ? 213 ILE C CG1 1 
ATOM   7070  C CG2 . ILE C 1 194 ? 54.874  -15.226 149.011 1.00 47.21  ? 213 ILE C CG2 1 
ATOM   7071  C CD1 . ILE C 1 194 ? 55.776  -15.441 151.820 1.00 44.85  ? 213 ILE C CD1 1 
ATOM   7072  N N   . ILE C 1 195 ? 53.781  -17.236 147.067 1.00 47.92  ? 214 ILE C N   1 
ATOM   7073  C CA  . ILE C 1 195 ? 52.424  -17.341 146.538 1.00 46.89  ? 214 ILE C CA  1 
ATOM   7074  C C   . ILE C 1 195 ? 52.091  -18.786 146.219 1.00 47.76  ? 214 ILE C C   1 
ATOM   7075  O O   . ILE C 1 195 ? 51.026  -19.285 146.588 1.00 45.93  ? 214 ILE C O   1 
ATOM   7076  C CB  . ILE C 1 195 ? 52.261  -16.451 145.292 1.00 48.71  ? 214 ILE C CB  1 
ATOM   7077  C CG1 . ILE C 1 195 ? 52.462  -15.013 145.719 1.00 47.56  ? 214 ILE C CG1 1 
ATOM   7078  C CG2 . ILE C 1 195 ? 50.913  -16.640 144.651 1.00 48.11  ? 214 ILE C CG2 1 
ATOM   7079  C CD1 . ILE C 1 195 ? 52.761  -14.116 144.614 1.00 50.07  ? 214 ILE C CD1 1 
ATOM   7080  N N   . GLN C 1 196 ? 52.979  -19.467 145.504 1.00 48.59  ? 215 GLN C N   1 
ATOM   7081  C CA  . GLN C 1 196 ? 52.779  -20.894 145.258 1.00 49.71  ? 215 GLN C CA  1 
ATOM   7082  C C   . GLN C 1 196 ? 52.616  -21.679 146.567 1.00 47.67  ? 215 GLN C C   1 
ATOM   7083  O O   . GLN C 1 196 ? 51.727  -22.524 146.688 1.00 46.84  ? 215 GLN C O   1 
ATOM   7084  C CB  . GLN C 1 196 ? 53.945  -21.461 144.448 1.00 53.02  ? 215 GLN C CB  1 
ATOM   7085  C CG  . GLN C 1 196 ? 53.712  -22.879 143.992 1.00 54.31  ? 215 GLN C CG  1 
ATOM   7086  C CD  . GLN C 1 196 ? 54.840  -23.406 143.147 1.00 57.15  ? 215 GLN C CD  1 
ATOM   7087  O OE1 . GLN C 1 196 ? 56.007  -23.039 143.348 1.00 58.04  ? 215 GLN C OE1 1 
ATOM   7088  N NE2 . GLN C 1 196 ? 54.505  -24.257 142.175 1.00 58.61  ? 215 GLN C NE2 1 
ATOM   7089  N N   . GLU C 1 197 ? 53.469  -21.390 147.566 1.00 50.42  ? 216 GLU C N   1 
ATOM   7090  C CA  . GLU C 1 197 ? 53.405  -22.083 148.849 1.00 48.79  ? 216 GLU C CA  1 
ATOM   7091  C C   . GLU C 1 197 ? 52.130  -21.758 149.622 1.00 45.84  ? 216 GLU C C   1 
ATOM   7092  O O   . GLU C 1 197 ? 51.629  -22.601 150.380 1.00 44.86  ? 216 GLU C O   1 
ATOM   7093  C CB  . GLU C 1 197 ? 54.623  -21.703 149.692 1.00 49.11  ? 216 GLU C CB  1 
ATOM   7094  C CG  . GLU C 1 197 ? 55.431  -22.838 150.184 1.00 49.31  ? 216 GLU C CG  1 
ATOM   7095  C CD  . GLU C 1 197 ? 56.510  -22.447 151.225 1.00 50.21  ? 216 GLU C CD  1 
ATOM   7096  O OE1 . GLU C 1 197 ? 57.527  -21.828 150.812 1.00 51.75  ? 216 GLU C OE1 1 
ATOM   7097  O OE2 . GLU C 1 197 ? 56.381  -22.788 152.446 1.00 50.40  ? 216 GLU C OE2 1 
ATOM   7098  N N   . THR C 1 198 ? 51.615  -20.538 149.483 1.00 47.97  ? 217 THR C N   1 
ATOM   7099  C CA  . THR C 1 198 ? 50.355  -20.186 150.133 1.00 45.02  ? 217 THR C CA  1 
ATOM   7100  C C   . THR C 1 198 ? 49.240  -21.086 149.634 1.00 44.66  ? 217 THR C C   1 
ATOM   7101  O O   . THR C 1 198 ? 48.424  -21.601 150.410 1.00 42.67  ? 217 THR C O   1 
ATOM   7102  C CB  . THR C 1 198 ? 49.980  -18.708 149.852 1.00 43.79  ? 217 THR C CB  1 
ATOM   7103  O OG1 . THR C 1 198 ? 50.968  -17.819 150.378 1.00 44.14  ? 217 THR C OG1 1 
ATOM   7104  C CG2 . THR C 1 198 ? 48.600  -18.380 150.457 1.00 40.61  ? 217 THR C CG2 1 
ATOM   7105  N N   . ARG C 1 199 ? 49.170  -21.238 148.313 1.00 46.50  ? 218 ARG C N   1 
ATOM   7106  C CA  . ARG C 1 199 ? 48.162  -22.089 147.698 1.00 46.63  ? 218 ARG C CA  1 
ATOM   7107  C C   . ARG C 1 199 ? 48.321  -23.533 148.165 1.00 47.83  ? 218 ARG C C   1 
ATOM   7108  O O   . ARG C 1 199 ? 47.336  -24.171 148.555 1.00 46.53  ? 218 ARG C O   1 
ATOM   7109  C CB  . ARG C 1 199 ? 48.249  -21.943 146.167 1.00 49.64  ? 218 ARG C CB  1 
ATOM   7110  C CG  . ARG C 1 199 ? 47.287  -22.824 145.365 1.00 50.06  ? 218 ARG C CG  1 
ATOM   7111  C CD  . ARG C 1 199 ? 45.873  -22.618 145.800 1.00 44.99  ? 218 ARG C CD  1 
ATOM   7112  N NE  . ARG C 1 199 ? 45.489  -21.248 145.534 1.00 42.87  ? 218 ARG C NE  1 
ATOM   7113  C CZ  . ARG C 1 199 ? 44.331  -20.710 145.879 1.00 40.07  ? 218 ARG C CZ  1 
ATOM   7114  N NH1 . ARG C 1 199 ? 43.453  -21.371 146.608 1.00 39.05  ? 218 ARG C NH1 1 
ATOM   7115  N NH2 . ARG C 1 199 ? 44.033  -19.486 145.449 1.00 39.49  ? 218 ARG C NH2 1 
ATOM   7116  N N   . GLN C 1 200 ? 49.557  -24.031 148.224 1.00 43.92  ? 219 GLN C N   1 
ATOM   7117  C CA  . GLN C 1 200 ? 49.778  -25.386 148.715 1.00 44.72  ? 219 GLN C CA  1 
ATOM   7118  C C   . GLN C 1 200 ? 49.309  -25.566 150.150 1.00 42.60  ? 219 GLN C C   1 
ATOM   7119  O O   . GLN C 1 200 ? 48.774  -26.618 150.498 1.00 43.62  ? 219 GLN C O   1 
ATOM   7120  C CB  . GLN C 1 200 ? 51.248  -25.759 148.596 1.00 46.73  ? 219 GLN C CB  1 
ATOM   7121  C CG  . GLN C 1 200 ? 51.714  -25.798 147.181 1.00 49.82  ? 219 GLN C CG  1 
ATOM   7122  C CD  . GLN C 1 200 ? 53.185  -25.996 147.065 1.00 52.01  ? 219 GLN C CD  1 
ATOM   7123  O OE1 . GLN C 1 200 ? 53.914  -25.944 148.053 1.00 51.02  ? 219 GLN C OE1 1 
ATOM   7124  N NE2 . GLN C 1 200 ? 53.647  -26.195 145.854 1.00 55.36  ? 219 GLN C NE2 1 
ATOM   7125  N N   . LYS C 1 201 ? 49.490  -24.567 150.992 1.00 46.54  ? 220 LYS C N   1 
ATOM   7126  C CA  . LYS C 1 201 ? 49.172  -24.750 152.401 1.00 44.45  ? 220 LYS C CA  1 
ATOM   7127  C C   . LYS C 1 201 ? 47.727  -24.454 152.757 1.00 42.20  ? 220 LYS C C   1 
ATOM   7128  O O   . LYS C 1 201 ? 47.267  -24.910 153.810 1.00 42.42  ? 220 LYS C O   1 
ATOM   7129  C CB  . LYS C 1 201 ? 50.078  -23.865 153.270 1.00 44.60  ? 220 LYS C CB  1 
ATOM   7130  C CG  . LYS C 1 201 ? 51.543  -24.050 152.975 1.00 47.92  ? 220 LYS C CG  1 
ATOM   7131  C CD  . LYS C 1 201 ? 52.296  -24.597 154.167 1.00 47.95  ? 220 LYS C CD  1 
ATOM   7132  C CE  . LYS C 1 201 ? 53.807  -24.399 153.978 1.00 49.73  ? 220 LYS C CE  1 
ATOM   7133  N NZ  . LYS C 1 201 ? 54.527  -24.406 155.263 1.00 49.37  ? 220 LYS C NZ  1 
ATOM   7134  N N   . ILE C 1 202 ? 46.997  -23.702 151.919 1.00 45.78  ? 221 ILE C N   1 
ATOM   7135  C CA  . ILE C 1 202 ? 45.580  -23.445 152.190 1.00 44.37  ? 221 ILE C CA  1 
ATOM   7136  C C   . ILE C 1 202 ? 44.617  -24.266 151.333 1.00 44.75  ? 221 ILE C C   1 
ATOM   7137  O O   . ILE C 1 202 ? 43.473  -24.497 151.701 1.00 44.15  ? 221 ILE C O   1 
ATOM   7138  C CB  . ILE C 1 202 ? 45.247  -21.947 152.020 1.00 43.18  ? 221 ILE C CB  1 
ATOM   7139  C CG1 . ILE C 1 202 ? 45.297  -21.517 150.567 1.00 43.27  ? 221 ILE C CG1 1 
ATOM   7140  C CG2 . ILE C 1 202 ? 46.192  -21.100 152.809 1.00 43.67  ? 221 ILE C CG2 1 
ATOM   7141  C CD1 . ILE C 1 202 ? 44.952  -20.076 150.410 1.00 42.51  ? 221 ILE C CD1 1 
ATOM   7142  N N   . GLY C 1 203 ? 45.072  -24.711 150.182 1.00 48.43  ? 222 GLY C N   1 
ATOM   7143  C CA  . GLY C 1 203 ? 44.179  -25.463 149.309 1.00 49.60  ? 222 GLY C CA  1 
ATOM   7144  C C   . GLY C 1 203 ? 43.604  -24.632 148.170 1.00 47.75  ? 222 GLY C C   1 
ATOM   7145  O O   . GLY C 1 203 ? 43.807  -23.421 148.045 1.00 45.34  ? 222 GLY C O   1 
ATOM   7146  N N   . ASP C 1 204 ? 42.878  -25.323 147.310 1.00 49.09  ? 223 ASP C N   1 
ATOM   7147  C CA  . ASP C 1 204 ? 42.352  -24.766 146.068 1.00 48.34  ? 223 ASP C CA  1 
ATOM   7148  C C   . ASP C 1 204 ? 41.007  -24.066 146.247 1.00 46.54  ? 223 ASP C C   1 
ATOM   7149  O O   . ASP C 1 204 ? 40.625  -23.237 145.405 1.00 45.23  ? 223 ASP C O   1 
ATOM   7150  C CB  . ASP C 1 204 ? 42.248  -25.901 145.034 1.00 50.46  ? 223 ASP C CB  1 
ATOM   7151  C CG  . ASP C 1 204 ? 43.574  -26.681 144.886 1.00 52.36  ? 223 ASP C CG  1 
ATOM   7152  O OD1 . ASP C 1 204 ? 44.662  -26.040 144.889 1.00 52.01  ? 223 ASP C OD1 1 
ATOM   7153  O OD2 . ASP C 1 204 ? 43.520  -27.948 144.810 1.00 54.48  ? 223 ASP C OD2 1 
ATOM   7154  N N   . ASP C 1 205 ? 40.300  -24.377 147.335 1.00 49.55  ? 224 ASP C N   1 
ATOM   7155  C CA  . ASP C 1 205 ? 38.975  -23.867 147.659 1.00 48.94  ? 224 ASP C CA  1 
ATOM   7156  C C   . ASP C 1 205 ? 39.036  -22.626 148.576 1.00 47.46  ? 224 ASP C C   1 
ATOM   7157  O O   . ASP C 1 205 ? 38.013  -22.215 149.138 1.00 46.82  ? 224 ASP C O   1 
ATOM   7158  C CB  . ASP C 1 205 ? 38.131  -25.008 148.267 1.00 50.49  ? 224 ASP C CB  1 
ATOM   7159  C CG  . ASP C 1 205 ? 38.864  -25.841 149.421 1.00 52.12  ? 224 ASP C CG  1 
ATOM   7160  O OD1 . ASP C 1 205 ? 39.944  -25.438 149.928 1.00 51.93  ? 224 ASP C OD1 1 
ATOM   7161  O OD2 . ASP C 1 205 ? 38.333  -26.941 149.812 1.00 54.59  ? 224 ASP C OD2 1 
ATOM   7162  N N   . LYS C 1 206 ? 40.208  -21.996 148.692 1.00 44.77  ? 225 LYS C N   1 
ATOM   7163  C CA  . LYS C 1 206 ? 40.411  -20.849 149.558 1.00 43.53  ? 225 LYS C CA  1 
ATOM   7164  C C   . LYS C 1 206 ? 40.897  -19.704 148.704 1.00 43.08  ? 225 LYS C C   1 
ATOM   7165  O O   . LYS C 1 206 ? 41.565  -19.926 147.686 1.00 44.33  ? 225 LYS C O   1 
ATOM   7166  C CB  . LYS C 1 206 ? 41.446  -21.102 150.633 1.00 44.26  ? 225 LYS C CB  1 
ATOM   7167  C CG  . LYS C 1 206 ? 41.076  -22.228 151.537 1.00 44.82  ? 225 LYS C CG  1 
ATOM   7168  C CD  . LYS C 1 206 ? 39.951  -21.836 152.489 1.00 43.61  ? 225 LYS C CD  1 
ATOM   7169  C CE  . LYS C 1 206 ? 39.842  -22.928 153.538 1.00 44.70  ? 225 LYS C CE  1 
ATOM   7170  N NZ  . LYS C 1 206 ? 39.068  -22.485 154.713 1.00 43.61  ? 225 LYS C NZ  1 
ATOM   7171  N N   . LEU C 1 207 ? 40.590  -18.488 149.139 1.00 41.93  ? 226 LEU C N   1 
ATOM   7172  C CA  . LEU C 1 207 ? 40.796  -17.298 148.315 1.00 41.23  ? 226 LEU C CA  1 
ATOM   7173  C C   . LEU C 1 207 ? 42.148  -16.676 148.627 1.00 41.65  ? 226 LEU C C   1 
ATOM   7174  O O   . LEU C 1 207 ? 42.536  -16.552 149.794 1.00 41.77  ? 226 LEU C O   1 
ATOM   7175  C CB  . LEU C 1 207 ? 39.678  -16.285 148.554 1.00 39.09  ? 226 LEU C CB  1 
ATOM   7176  C CG  . LEU C 1 207 ? 38.377  -16.761 147.916 1.00 38.69  ? 226 LEU C CG  1 
ATOM   7177  C CD1 . LEU C 1 207 ? 37.195  -16.132 148.638 1.00 35.93  ? 226 LEU C CD1 1 
ATOM   7178  C CD2 . LEU C 1 207 ? 38.353  -16.529 146.390 1.00 39.84  ? 226 LEU C CD2 1 
ATOM   7179  N N   . ILE C 1 208 ? 42.874  -16.326 147.588 1.00 40.44  ? 227 ILE C N   1 
ATOM   7180  C CA  . ILE C 1 208 ? 44.100  -15.561 147.721 1.00 40.86  ? 227 ILE C CA  1 
ATOM   7181  C C   . ILE C 1 208 ? 43.813  -14.224 147.068 1.00 39.94  ? 227 ILE C C   1 
ATOM   7182  O O   . ILE C 1 208 ? 43.595  -14.153 145.858 1.00 40.29  ? 227 ILE C O   1 
ATOM   7183  C CB  . ILE C 1 208 ? 45.292  -16.265 147.071 1.00 42.61  ? 227 ILE C CB  1 
ATOM   7184  C CG1 . ILE C 1 208 ? 45.568  -17.596 147.752 1.00 43.67  ? 227 ILE C CG1 1 
ATOM   7185  C CG2 . ILE C 1 208 ? 46.510  -15.375 147.141 1.00 43.55  ? 227 ILE C CG2 1 
ATOM   7186  C CD1 . ILE C 1 208 ? 46.702  -18.388 147.095 1.00 45.26  ? 227 ILE C CD1 1 
ATOM   7187  N N   . VAL C 1 209 ? 43.774  -13.173 147.879 1.00 40.98  ? 228 VAL C N   1 
ATOM   7188  C CA  . VAL C 1 209 ? 43.540  -11.799 147.434 1.00 40.13  ? 228 VAL C CA  1 
ATOM   7189  C C   . VAL C 1 209 ? 44.832  -11.026 147.619 1.00 41.08  ? 228 VAL C C   1 
ATOM   7190  O O   . VAL C 1 209 ? 45.473  -11.136 148.658 1.00 41.79  ? 228 VAL C O   1 
ATOM   7191  C CB  . VAL C 1 209 ? 42.422  -11.142 148.252 1.00 38.14  ? 228 VAL C CB  1 
ATOM   7192  C CG1 . VAL C 1 209 ? 42.008  -9.812  147.651 1.00 36.77  ? 228 VAL C CG1 1 
ATOM   7193  C CG2 . VAL C 1 209 ? 41.270  -12.062 148.353 1.00 37.41  ? 228 VAL C CG2 1 
ATOM   7194  N N   . TYR C 1 210 ? 45.218  -10.238 146.639 1.00 40.49  ? 229 TYR C N   1 
ATOM   7195  C CA  . TYR C 1 210 ? 46.407  -9.453  146.865 1.00 41.40  ? 229 TYR C CA  1 
ATOM   7196  C C   . TYR C 1 210 ? 46.294  -8.021  146.343 1.00 40.92  ? 229 TYR C C   1 
ATOM   7197  O O   . TYR C 1 210 ? 45.393  -7.640  145.593 1.00 40.41  ? 229 TYR C O   1 
ATOM   7198  C CB  . TYR C 1 210 ? 47.606  -10.129 146.248 1.00 43.34  ? 229 TYR C CB  1 
ATOM   7199  C CG  . TYR C 1 210 ? 47.741  -9.880  144.785 1.00 43.60  ? 229 TYR C CG  1 
ATOM   7200  C CD1 . TYR C 1 210 ? 47.035  -10.650 143.865 1.00 43.62  ? 229 TYR C CD1 1 
ATOM   7201  C CD2 . TYR C 1 210 ? 48.595  -8.891  144.301 1.00 44.59  ? 229 TYR C CD2 1 
ATOM   7202  C CE1 . TYR C 1 210 ? 47.178  -10.458 142.524 1.00 44.41  ? 229 TYR C CE1 1 
ATOM   7203  C CE2 . TYR C 1 210 ? 48.743  -8.691  142.925 1.00 45.37  ? 229 TYR C CE2 1 
ATOM   7204  C CZ  . TYR C 1 210 ? 48.028  -9.493  142.054 1.00 45.31  ? 229 TYR C CZ  1 
ATOM   7205  O OH  . TYR C 1 210 ? 48.132  -9.345  140.696 1.00 46.55  ? 229 TYR C OH  1 
ATOM   7206  N N   . ASN C 1 211 ? 47.246  -7.231  146.805 1.00 41.34  ? 230 ASN C N   1 
ATOM   7207  C CA  . ASN C 1 211 ? 47.383  -5.822  146.513 1.00 41.48  ? 230 ASN C CA  1 
ATOM   7208  C C   . ASN C 1 211 ? 48.740  -5.641  145.852 1.00 43.49  ? 230 ASN C C   1 
ATOM   7209  O O   . ASN C 1 211 ? 49.777  -5.784  146.513 1.00 44.92  ? 230 ASN C O   1 
ATOM   7210  C CB  . ASN C 1 211 ? 47.261  -5.037  147.818 1.00 41.07  ? 230 ASN C CB  1 
ATOM   7211  C CG  . ASN C 1 211 ? 46.850  -3.607  147.597 1.00 41.05  ? 230 ASN C CG  1 
ATOM   7212  O OD1 . ASN C 1 211 ? 46.439  -3.222  146.505 1.00 41.65  ? 230 ASN C OD1 1 
ATOM   7213  N ND2 . ASN C 1 211 ? 46.937  -2.814  148.651 1.00 41.04  ? 230 ASN C ND2 1 
ATOM   7214  N N   . GLY C 1 212 ? 48.740  -5.401  144.532 1.00 43.15  ? 231 GLY C N   1 
ATOM   7215  C CA  . GLY C 1 212 ? 47.582  -5.494  143.661 1.00 41.93  ? 231 GLY C CA  1 
ATOM   7216  C C   . GLY C 1 212 ? 47.771  -4.810  142.336 1.00 42.78  ? 231 GLY C C   1 
ATOM   7217  O O   . GLY C 1 212 ? 48.877  -4.650  141.856 1.00 44.85  ? 231 GLY C O   1 
ATOM   7218  N N   . ILE C 1 213 ? 46.671  -4.379  141.757 1.00 42.95  ? 232 ILE C N   1 
ATOM   7219  C CA  . ILE C 1 213 ? 46.703  -3.585  140.532 1.00 43.51  ? 232 ILE C CA  1 
ATOM   7220  C C   . ILE C 1 213 ? 46.949  -2.119  140.866 1.00 43.81  ? 232 ILE C C   1 
ATOM   7221  O O   . ILE C 1 213 ? 46.336  -1.552  141.781 1.00 42.85  ? 232 ILE C O   1 
ATOM   7222  C CB  . ILE C 1 213 ? 45.393  -3.754  139.755 1.00 42.63  ? 232 ILE C CB  1 
ATOM   7223  C CG1 . ILE C 1 213 ? 45.171  -5.219  139.379 1.00 42.91  ? 232 ILE C CG1 1 
ATOM   7224  C CG2 . ILE C 1 213 ? 45.430  -2.975  138.480 1.00 43.59  ? 232 ILE C CG2 1 
ATOM   7225  C CD1 . ILE C 1 213 ? 43.689  -5.569  139.132 1.00 41.27  ? 232 ILE C CD1 1 
ATOM   7226  N N   . ARG C 1 214 ? 47.843  -1.495  140.111 1.00 41.49  ? 233 ARG C N   1 
ATOM   7227  C CA  . ARG C 1 214 ? 48.355  -0.179  140.449 1.00 42.47  ? 233 ARG C CA  1 
ATOM   7228  C C   . ARG C 1 214 ? 48.812  0.468   139.160 1.00 43.89  ? 233 ARG C C   1 
ATOM   7229  O O   . ARG C 1 214 ? 49.620  -0.133  138.436 1.00 45.52  ? 233 ARG C O   1 
ATOM   7230  C CB  . ARG C 1 214 ? 49.526  -0.279  141.444 1.00 44.07  ? 233 ARG C CB  1 
ATOM   7231  C CG  . ARG C 1 214 ? 50.149  1.072   141.845 1.00 46.00  ? 233 ARG C CG  1 
ATOM   7232  C CD  . ARG C 1 214 ? 49.161  1.889   142.643 1.00 44.77  ? 233 ARG C CD  1 
ATOM   7233  N NE  . ARG C 1 214 ? 48.663  1.121   143.777 1.00 43.26  ? 233 ARG C NE  1 
ATOM   7234  C CZ  . ARG C 1 214 ? 49.338  0.914   144.899 1.00 44.17  ? 233 ARG C CZ  1 
ATOM   7235  N NH1 . ARG C 1 214 ? 50.534  1.439   145.087 1.00 46.18  ? 233 ARG C NH1 1 
ATOM   7236  N NH2 . ARG C 1 214 ? 48.787  0.187   145.866 1.00 43.07  ? 233 ARG C NH2 1 
ATOM   7237  N N   . SER C 1 215 ? 48.313  1.684   138.888 1.00 43.65  ? 234 SER C N   1 
ATOM   7238  C CA  . SER C 1 215 ? 48.741  2.460   137.735 1.00 45.12  ? 234 SER C CA  1 
ATOM   7239  C C   . SER C 1 215 ? 49.244  3.835   138.150 1.00 46.23  ? 234 SER C C   1 
ATOM   7240  O O   . SER C 1 215 ? 48.465  4.668   138.643 1.00 45.24  ? 234 SER C O   1 
ATOM   7241  C CB  . SER C 1 215 ? 47.609  2.673   136.747 1.00 44.62  ? 234 SER C CB  1 
ATOM   7242  O OG  . SER C 1 215 ? 47.149  1.465   136.259 1.00 44.59  ? 234 SER C OG  1 
ATOM   7243  N N   . THR C 1 216 ? 50.515  4.098   137.867 1.00 45.76  ? 235 THR C N   1 
ATOM   7244  C CA  . THR C 1 216 ? 51.078  5.417   138.072 1.00 47.56  ? 235 THR C CA  1 
ATOM   7245  C C   . THR C 1 216 ? 51.911  5.799   136.863 1.00 50.16  ? 235 THR C C   1 
ATOM   7246  O O   . THR C 1 216 ? 52.207  4.950   136.022 1.00 51.49  ? 235 THR C O   1 
ATOM   7247  C CB  . THR C 1 216 ? 51.938  5.445   139.330 1.00 48.66  ? 235 THR C CB  1 
ATOM   7248  O OG1 . THR C 1 216 ? 53.202  4.849   139.031 1.00 50.94  ? 235 THR C OG1 1 
ATOM   7249  C CG2 . THR C 1 216 ? 51.216  4.720   140.462 1.00 47.08  ? 235 THR C CG2 1 
ATOM   7250  N N   . PRO C 1 217 ? 52.280  7.068   136.733 1.00 47.05  ? 236 PRO C N   1 
ATOM   7251  C CA  . PRO C 1 217 ? 53.024  7.477   135.530 1.00 49.97  ? 236 PRO C CA  1 
ATOM   7252  C C   . PRO C 1 217 ? 54.372  6.785   135.395 1.00 53.43  ? 236 PRO C C   1 
ATOM   7253  O O   . PRO C 1 217 ? 54.798  6.469   134.275 1.00 55.90  ? 236 PRO C O   1 
ATOM   7254  C CB  . PRO C 1 217 ? 53.143  8.995   135.721 1.00 50.24  ? 236 PRO C CB  1 
ATOM   7255  C CG  . PRO C 1 217 ? 51.921  9.344   136.564 1.00 47.96  ? 236 PRO C CG  1 
ATOM   7256  C CD  . PRO C 1 217 ? 51.781  8.221   137.515 1.00 46.47  ? 236 PRO C CD  1 
ATOM   7257  N N   . ASP C 1 218 ? 55.066  6.559   136.516 1.00 51.61  ? 237 ASP C N   1 
ATOM   7258  C CA  . ASP C 1 218 ? 56.432  6.050   136.494 1.00 55.09  ? 237 ASP C CA  1 
ATOM   7259  C C   . ASP C 1 218 ? 56.465  4.535   136.587 1.00 54.89  ? 237 ASP C C   1 
ATOM   7260  O O   . ASP C 1 218 ? 57.444  3.922   136.144 1.00 57.42  ? 237 ASP C O   1 
ATOM   7261  C CB  . ASP C 1 218 ? 57.243  6.684   137.627 1.00 56.67  ? 237 ASP C CB  1 
ATOM   7262  N N   . TRP C 1 219 ? 55.384  3.918   137.069 1.00 56.40  ? 238 TRP C N   1 
ATOM   7263  C CA  . TRP C 1 219 ? 55.365  2.486   137.311 1.00 55.17  ? 238 TRP C CA  1 
ATOM   7264  C C   . TRP C 1 219 ? 53.934  1.989   137.429 1.00 52.07  ? 238 TRP C C   1 
ATOM   7265  O O   . TRP C 1 219 ? 53.120  2.601   138.129 1.00 50.55  ? 238 TRP C O   1 
ATOM   7266  C CB  . TRP C 1 219 ? 56.122  2.164   138.596 1.00 55.42  ? 238 TRP C CB  1 
ATOM   7267  C CG  . TRP C 1 219 ? 56.209  0.702   138.929 1.00 55.05  ? 238 TRP C CG  1 
ATOM   7268  C CD1 . TRP C 1 219 ? 57.228  -0.140  138.609 1.00 56.80  ? 238 TRP C CD1 1 
ATOM   7269  C CD2 . TRP C 1 219 ? 55.257  -0.076  139.651 1.00 52.81  ? 238 TRP C CD2 1 
ATOM   7270  N NE1 . TRP C 1 219 ? 56.965  -1.395  139.078 1.00 55.78  ? 238 TRP C NE1 1 
ATOM   7271  C CE2 . TRP C 1 219 ? 55.758  -1.379  139.724 1.00 53.21  ? 238 TRP C CE2 1 
ATOM   7272  C CE3 . TRP C 1 219 ? 54.021  0.200   140.236 1.00 50.45  ? 238 TRP C CE3 1 
ATOM   7273  C CZ2 . TRP C 1 219 ? 55.080  -2.393  140.359 1.00 51.36  ? 238 TRP C CZ2 1 
ATOM   7274  C CZ3 . TRP C 1 219 ? 53.344  -0.834  140.863 1.00 48.81  ? 238 TRP C CZ3 1 
ATOM   7275  C CH2 . TRP C 1 219 ? 53.883  -2.095  140.932 1.00 49.38  ? 238 TRP C CH2 1 
ATOM   7276  N N   . SER C 1 220 ? 53.649  0.851   136.781 1.00 53.08  ? 239 SER C N   1 
ATOM   7277  C CA  . SER C 1 220 ? 52.323  0.247   136.777 1.00 50.36  ? 239 SER C CA  1 
ATOM   7278  C C   . SER C 1 220 ? 52.448  -1.265  136.907 1.00 49.05  ? 239 SER C C   1 
ATOM   7279  O O   . SER C 1 220 ? 53.484  -1.858  136.578 1.00 51.31  ? 239 SER C O   1 
ATOM   7280  C CB  . SER C 1 220 ? 51.550  0.575   135.490 1.00 51.00  ? 239 SER C CB  1 
ATOM   7281  O OG  . SER C 1 220 ? 51.425  1.986   135.296 1.00 51.81  ? 239 SER C OG  1 
ATOM   7282  N N   . ALA C 1 221 ? 51.364  -1.886  137.376 1.00 50.50  ? 240 ALA C N   1 
ATOM   7283  C CA  . ALA C 1 221 ? 51.282  -3.333  137.454 1.00 49.41  ? 240 ALA C CA  1 
ATOM   7284  C C   . ALA C 1 221 ? 49.837  -3.755  137.259 1.00 46.93  ? 240 ALA C C   1 
ATOM   7285  O O   . ALA C 1 221 ? 48.930  -3.104  137.784 1.00 45.44  ? 240 ALA C O   1 
ATOM   7286  C CB  . ALA C 1 221 ? 51.776  -3.856  138.799 1.00 49.71  ? 240 ALA C CB  1 
ATOM   7287  N N   . GLY C 1 222 ? 49.630  -4.835  136.508 1.00 49.64  ? 241 GLY C N   1 
ATOM   7288  C CA  . GLY C 1 222 ? 48.321  -5.416  136.331 1.00 47.81  ? 241 GLY C CA  1 
ATOM   7289  C C   . GLY C 1 222 ? 48.171  -6.706  137.110 1.00 46.94  ? 241 GLY C C   1 
ATOM   7290  O O   . GLY C 1 222 ? 48.992  -7.060  137.956 1.00 47.85  ? 241 GLY C O   1 
ATOM   7291  N N   . PHE C 1 223 ? 47.090  -7.411  136.819 1.00 47.32  ? 242 PHE C N   1 
ATOM   7292  C CA  . PHE C 1 223 ? 46.850  -8.680  137.485 1.00 46.59  ? 242 PHE C CA  1 
ATOM   7293  C C   . PHE C 1 223 ? 47.955  -9.672  137.143 1.00 48.41  ? 242 PHE C C   1 
ATOM   7294  O O   . PHE C 1 223 ? 48.272  -9.872  135.971 1.00 50.30  ? 242 PHE C O   1 
ATOM   7295  C CB  . PHE C 1 223 ? 45.494  -9.236  137.060 1.00 45.44  ? 242 PHE C CB  1 
ATOM   7296  C CG  . PHE C 1 223 ? 44.857  -10.094 138.078 1.00 44.39  ? 242 PHE C CG  1 
ATOM   7297  C CD1 . PHE C 1 223 ? 45.418  -11.294 138.425 1.00 45.78  ? 242 PHE C CD1 1 
ATOM   7298  C CD2 . PHE C 1 223 ? 43.699  -9.704  138.682 1.00 43.10  ? 242 PHE C CD2 1 
ATOM   7299  C CE1 . PHE C 1 223 ? 44.828  -12.103 139.379 1.00 45.59  ? 242 PHE C CE1 1 
ATOM   7300  C CE2 . PHE C 1 223 ? 43.099  -10.479 139.620 1.00 43.08  ? 242 PHE C CE2 1 
ATOM   7301  C CZ  . PHE C 1 223 ? 43.661  -11.681 139.988 1.00 44.14  ? 242 PHE C CZ  1 
ATOM   7302  N N   . ASP C 1 224 ? 48.510  -10.330 138.168 1.00 51.65  ? 243 ASP C N   1 
ATOM   7303  C CA  . ASP C 1 224 ? 49.659  -11.220 138.001 1.00 53.80  ? 243 ASP C CA  1 
ATOM   7304  C C   . ASP C 1 224 ? 49.483  -12.496 138.839 1.00 53.06  ? 243 ASP C C   1 
ATOM   7305  O O   . ASP C 1 224 ? 48.511  -12.673 139.580 1.00 51.90  ? 243 ASP C O   1 
ATOM   7306  C CB  . ASP C 1 224 ? 50.952  -10.471 138.369 1.00 56.61  ? 243 ASP C CB  1 
ATOM   7307  C CG  . ASP C 1 224 ? 52.210  -11.128 137.800 1.00 60.17  ? 243 ASP C CG  1 
ATOM   7308  O OD1 . ASP C 1 224 ? 52.095  -12.133 137.076 1.00 60.84  ? 243 ASP C OD1 1 
ATOM   7309  O OD2 . ASP C 1 224 ? 53.331  -10.649 138.087 1.00 62.35  ? 243 ASP C OD2 1 
ATOM   7310  N N   . PHE C 1 225 ? 50.431  -13.410 138.704 1.00 55.76  ? 244 PHE C N   1 
ATOM   7311  C CA  . PHE C 1 225 ? 50.447  -14.668 139.474 1.00 55.96  ? 244 PHE C CA  1 
ATOM   7312  C C   . PHE C 1 225 ? 49.173  -15.501 139.269 1.00 54.70  ? 244 PHE C C   1 
ATOM   7313  O O   . PHE C 1 225 ? 48.827  -16.369 140.098 1.00 54.29  ? 244 PHE C O   1 
ATOM   7314  C CB  . PHE C 1 225 ? 50.691  -14.345 140.944 1.00 56.05  ? 244 PHE C CB  1 
ATOM   7315  C CG  . PHE C 1 225 ? 51.812  -13.380 141.132 1.00 57.26  ? 244 PHE C CG  1 
ATOM   7316  C CD1 . PHE C 1 225 ? 53.126  -13.813 141.008 1.00 59.25  ? 244 PHE C CD1 1 
ATOM   7317  C CD2 . PHE C 1 225 ? 51.563  -12.029 141.346 1.00 56.86  ? 244 PHE C CD2 1 
ATOM   7318  C CE1 . PHE C 1 225 ? 54.176  -12.898 141.157 1.00 60.37  ? 244 PHE C CE1 1 
ATOM   7319  C CE2 . PHE C 1 225 ? 52.598  -11.114 141.482 1.00 58.01  ? 244 PHE C CE2 1 
ATOM   7320  C CZ  . PHE C 1 225 ? 53.898  -11.533 141.387 1.00 59.76  ? 244 PHE C CZ  1 
ATOM   7321  N N   . ALA C 1 226 ? 48.532  -15.274 138.122 1.00 55.94  ? 245 ALA C N   1 
ATOM   7322  C CA  . ALA C 1 226 ? 47.146  -15.659 137.933 1.00 54.88  ? 245 ALA C CA  1 
ATOM   7323  C C   . ALA C 1 226 ? 46.922  -17.149 138.051 1.00 55.31  ? 245 ALA C C   1 
ATOM   7324  O O   . ALA C 1 226 ? 45.766  -17.568 138.199 1.00 54.35  ? 245 ALA C O   1 
ATOM   7325  C CB  . ALA C 1 226 ? 46.685  -15.144 136.567 1.00 55.16  ? 245 ALA C CB  1 
ATOM   7326  N N   . GLU C 1 227 ? 47.984  -17.962 137.986 1.00 53.46  ? 246 GLU C N   1 
ATOM   7327  C CA  . GLU C 1 227 ? 47.825  -19.393 138.189 1.00 54.09  ? 246 GLU C CA  1 
ATOM   7328  C C   . GLU C 1 227 ? 47.617  -19.728 139.658 1.00 53.29  ? 246 GLU C C   1 
ATOM   7329  O O   . GLU C 1 227 ? 47.320  -20.887 139.989 1.00 53.76  ? 246 GLU C O   1 
ATOM   7330  C CB  . GLU C 1 227 ? 49.046  -20.149 137.631 1.00 56.20  ? 246 GLU C CB  1 
ATOM   7331  N N   . TYR C 1 228 ? 47.797  -18.761 140.556 1.00 49.64  ? 247 TYR C N   1 
ATOM   7332  C CA  . TYR C 1 228 ? 47.577  -19.065 141.955 1.00 49.34  ? 247 TYR C CA  1 
ATOM   7333  C C   . TYR C 1 228 ? 46.683  -18.069 142.657 1.00 47.51  ? 247 TYR C C   1 
ATOM   7334  O O   . TYR C 1 228 ? 46.026  -18.441 143.626 1.00 47.75  ? 247 TYR C O   1 
ATOM   7335  C CB  . TYR C 1 228 ? 48.904  -19.139 142.675 1.00 50.59  ? 247 TYR C CB  1 
ATOM   7336  C CG  . TYR C 1 228 ? 49.758  -20.244 142.160 1.00 52.21  ? 247 TYR C CG  1 
ATOM   7337  C CD1 . TYR C 1 228 ? 51.022  -19.986 141.714 1.00 53.45  ? 247 TYR C CD1 1 
ATOM   7338  C CD2 . TYR C 1 228 ? 49.287  -21.543 142.095 1.00 52.91  ? 247 TYR C CD2 1 
ATOM   7339  C CE1 . TYR C 1 228 ? 51.837  -20.993 141.216 1.00 55.01  ? 247 TYR C CE1 1 
ATOM   7340  C CE2 . TYR C 1 228 ? 50.091  -22.544 141.619 1.00 54.92  ? 247 TYR C CE2 1 
ATOM   7341  C CZ  . TYR C 1 228 ? 51.389  -22.243 141.172 1.00 55.75  ? 247 TYR C CZ  1 
ATOM   7342  O OH  . TYR C 1 228 ? 52.241  -23.242 140.692 1.00 58.08  ? 247 TYR C OH  1 
ATOM   7343  N N   . THR C 1 229 ? 46.623  -16.817 142.201 1.00 48.31  ? 248 THR C N   1 
ATOM   7344  C CA  . THR C 1 229 ? 45.803  -15.843 142.890 1.00 47.00  ? 248 THR C CA  1 
ATOM   7345  C C   . THR C 1 229 ? 44.389  -15.872 142.348 1.00 45.74  ? 248 THR C C   1 
ATOM   7346  O O   . THR C 1 229 ? 44.159  -16.203 141.185 1.00 46.41  ? 248 THR C O   1 
ATOM   7347  C CB  . THR C 1 229 ? 46.405  -14.449 142.762 1.00 47.39  ? 248 THR C CB  1 
ATOM   7348  O OG1 . THR C 1 229 ? 46.583  -14.059 141.388 1.00 48.07  ? 248 THR C OG1 1 
ATOM   7349  C CG2 . THR C 1 229 ? 47.741  -14.414 143.498 1.00 48.64  ? 248 THR C CG2 1 
ATOM   7350  N N   . ASP C 1 230 ? 43.438  -15.532 143.209 1.00 42.87  ? 249 ASP C N   1 
ATOM   7351  C CA  . ASP C 1 230 ? 42.047  -15.393 142.813 1.00 42.10  ? 249 ASP C CA  1 
ATOM   7352  C C   . ASP C 1 230 ? 41.596  -13.945 142.591 1.00 41.45  ? 249 ASP C C   1 
ATOM   7353  O O   . ASP C 1 230 ? 40.658  -13.710 141.813 1.00 40.43  ? 249 ASP C O   1 
ATOM   7354  C CB  . ASP C 1 230 ? 41.135  -16.015 143.881 1.00 42.22  ? 249 ASP C CB  1 
ATOM   7355  C CG  . ASP C 1 230 ? 41.439  -17.453 144.157 1.00 43.25  ? 249 ASP C CG  1 
ATOM   7356  O OD1 . ASP C 1 230 ? 41.459  -18.269 143.189 1.00 44.11  ? 249 ASP C OD1 1 
ATOM   7357  O OD2 . ASP C 1 230 ? 41.648  -17.768 145.360 1.00 43.38  ? 249 ASP C OD2 1 
ATOM   7358  N N   . ALA C 1 231 ? 42.236  -12.976 143.253 1.00 40.42  ? 250 ALA C N   1 
ATOM   7359  C CA  . ALA C 1 231 ? 41.686  -11.633 143.375 1.00 39.38  ? 250 ALA C CA  1 
ATOM   7360  C C   . ALA C 1 231 ? 42.764  -10.572 143.535 1.00 39.48  ? 250 ALA C C   1 
ATOM   7361  O O   . ALA C 1 231 ? 43.798  -10.777 144.184 1.00 40.19  ? 250 ALA C O   1 
ATOM   7362  C CB  . ALA C 1 231 ? 40.735  -11.536 144.579 1.00 37.34  ? 250 ALA C CB  1 
ATOM   7363  N N   . ALA C 1 232 ? 42.491  -9.418  142.959 1.00 40.56  ? 251 ALA C N   1 
ATOM   7364  C CA  . ALA C 1 232 ? 43.414  -8.310  142.983 1.00 40.93  ? 251 ALA C CA  1 
ATOM   7365  C C   . ALA C 1 232 ? 42.616  -7.067  143.296 1.00 38.85  ? 251 ALA C C   1 
ATOM   7366  O O   . ALA C 1 232 ? 41.522  -6.835  142.760 1.00 37.12  ? 251 ALA C O   1 
ATOM   7367  C CB  . ALA C 1 232 ? 44.157  -8.160  141.669 1.00 42.03  ? 251 ALA C CB  1 
ATOM   7368  N N   . MET C 1 233 ? 43.181  -6.280  144.183 1.00 43.24  ? 252 MET C N   1 
ATOM   7369  C CA  . MET C 1 233 ? 42.616  -5.012  144.575 1.00 41.32  ? 252 MET C CA  1 
ATOM   7370  C C   . MET C 1 233 ? 43.252  -3.890  143.771 1.00 42.63  ? 252 MET C C   1 
ATOM   7371  O O   . MET C 1 233 ? 44.460  -3.896  143.524 1.00 45.17  ? 252 MET C O   1 
ATOM   7372  C CB  . MET C 1 233 ? 42.839  -4.791  146.073 1.00 41.53  ? 252 MET C CB  1 
ATOM   7373  C CG  . MET C 1 233 ? 42.287  -3.443  146.514 1.00 40.48  ? 252 MET C CG  1 
ATOM   7374  S SD  . MET C 1 233 ? 42.958  -3.031  148.127 1.00 40.63  ? 252 MET C SD  1 
ATOM   7375  C CE  . MET C 1 233 ? 41.383  -3.043  149.006 1.00 38.28  ? 252 MET C CE  1 
ATOM   7376  N N   . ILE C 1 234 ? 42.412  -2.947  143.362 1.00 38.49  ? 253 ILE C N   1 
ATOM   7377  C CA  . ILE C 1 234 ? 42.834  -1.648  142.833 1.00 39.32  ? 253 ILE C CA  1 
ATOM   7378  C C   . ILE C 1 234 ? 42.682  -0.682  144.005 1.00 38.38  ? 253 ILE C C   1 
ATOM   7379  O O   . ILE C 1 234 ? 41.611  -0.112  144.214 1.00 36.54  ? 253 ILE C O   1 
ATOM   7380  C CB  . ILE C 1 234 ? 41.982  -1.206  141.650 1.00 38.57  ? 253 ILE C CB  1 
ATOM   7381  C CG1 . ILE C 1 234 ? 42.030  -2.237  140.535 1.00 39.46  ? 253 ILE C CG1 1 
ATOM   7382  C CG2 . ILE C 1 234 ? 42.390  0.179   141.159 1.00 40.35  ? 253 ILE C CG2 1 
ATOM   7383  C CD1 . ILE C 1 234 ? 40.999  -1.972  139.467 1.00 38.16  ? 253 ILE C CD1 1 
ATOM   7384  N N   . GLU C 1 235 ? 43.757  -0.533  144.790 1.00 39.04  ? 254 GLU C N   1 
ATOM   7385  C CA  . GLU C 1 235 ? 43.685  0.168   146.066 1.00 38.07  ? 254 GLU C CA  1 
ATOM   7386  C C   . GLU C 1 235 ? 43.605  1.687   145.895 1.00 38.22  ? 254 GLU C C   1 
ATOM   7387  O O   . GLU C 1 235 ? 42.924  2.359   146.680 1.00 36.84  ? 254 GLU C O   1 
ATOM   7388  C CB  . GLU C 1 235 ? 44.904  -0.211  146.932 1.00 40.10  ? 254 GLU C CB  1 
ATOM   7389  C CG  . GLU C 1 235 ? 44.725  0.132   148.400 1.00 39.54  ? 254 GLU C CG  1 
ATOM   7390  C CD  . GLU C 1 235 ? 46.015  0.499   149.151 1.00 41.90  ? 254 GLU C CD  1 
ATOM   7391  O OE1 . GLU C 1 235 ? 47.143  0.076   148.743 1.00 43.89  ? 254 GLU C OE1 1 
ATOM   7392  O OE2 . GLU C 1 235 ? 45.880  1.224   150.188 1.00 41.61  ? 254 GLU C OE2 1 
ATOM   7393  N N   . HIS C 1 236 ? 44.252  2.229   144.873 1.00 37.74  ? 255 HIS C N   1 
ATOM   7394  C CA  . HIS C 1 236 ? 44.412  3.665   144.702 1.00 38.64  ? 255 HIS C CA  1 
ATOM   7395  C C   . HIS C 1 236 ? 43.619  4.230   143.534 1.00 38.06  ? 255 HIS C C   1 
ATOM   7396  O O   . HIS C 1 236 ? 44.094  5.120   142.825 1.00 40.03  ? 255 HIS C O   1 
ATOM   7397  C CB  . HIS C 1 236 ? 45.870  4.036   144.456 1.00 41.78  ? 255 HIS C CB  1 
ATOM   7398  C CG  . HIS C 1 236 ? 46.754  3.827   145.630 1.00 42.85  ? 255 HIS C CG  1 
ATOM   7399  N ND1 . HIS C 1 236 ? 48.106  4.076   145.589 1.00 45.11  ? 255 HIS C ND1 1 
ATOM   7400  C CD2 . HIS C 1 236 ? 46.480  3.410   146.883 1.00 41.91  ? 255 HIS C CD2 1 
ATOM   7401  C CE1 . HIS C 1 236 ? 48.628  3.827   146.771 1.00 45.55  ? 255 HIS C CE1 1 
ATOM   7402  N NE2 . HIS C 1 236 ? 47.662  3.417   147.571 1.00 43.99  ? 255 HIS C NE2 1 
ATOM   7403  N N   . PHE C 1 237 ? 42.401  3.763   143.294 1.00 41.69  ? 256 PHE C N   1 
ATOM   7404  C CA  . PHE C 1 237 ? 41.705  4.280   142.128 1.00 41.04  ? 256 PHE C CA  1 
ATOM   7405  C C   . PHE C 1 237 ? 41.452  5.767   142.264 1.00 41.20  ? 256 PHE C C   1 
ATOM   7406  O O   . PHE C 1 237 ? 40.768  6.197   143.195 1.00 39.55  ? 256 PHE C O   1 
ATOM   7407  C CB  . PHE C 1 237 ? 40.371  3.603   141.884 1.00 38.54  ? 256 PHE C CB  1 
ATOM   7408  C CG  . PHE C 1 237 ? 39.687  4.137   140.655 1.00 38.53  ? 256 PHE C CG  1 
ATOM   7409  C CD1 . PHE C 1 237 ? 40.189  3.854   139.398 1.00 40.31  ? 256 PHE C CD1 1 
ATOM   7410  C CD2 . PHE C 1 237 ? 38.597  4.958   140.763 1.00 37.36  ? 256 PHE C CD2 1 
ATOM   7411  C CE1 . PHE C 1 237 ? 39.594  4.365   138.261 1.00 40.25  ? 256 PHE C CE1 1 
ATOM   7412  C CE2 . PHE C 1 237 ? 37.999  5.487   139.642 1.00 37.86  ? 256 PHE C CE2 1 
ATOM   7413  C CZ  . PHE C 1 237 ? 38.491  5.192   138.382 1.00 39.01  ? 256 PHE C CZ  1 
ATOM   7414  N N   . GLY C 1 238 ? 41.966  6.542   141.308 1.00 40.20  ? 257 GLY C N   1 
ATOM   7415  C CA  . GLY C 1 238 ? 41.601  7.943   141.143 1.00 40.67  ? 257 GLY C CA  1 
ATOM   7416  C C   . GLY C 1 238 ? 42.143  8.879   142.197 1.00 41.97  ? 257 GLY C C   1 
ATOM   7417  O O   . GLY C 1 238 ? 41.644  9.990   142.349 1.00 42.61  ? 257 GLY C O   1 
ATOM   7418  N N   . HIS C 1 239 ? 43.141  8.444   142.957 1.00 41.95  ? 258 HIS C N   1 
ATOM   7419  C CA  . HIS C 1 239 ? 43.769  9.234   144.021 1.00 43.06  ? 258 HIS C CA  1 
ATOM   7420  C C   . HIS C 1 239 ? 45.254  8.878   144.036 1.00 45.67  ? 258 HIS C C   1 
ATOM   7421  O O   . HIS C 1 239 ? 45.748  8.160   143.151 1.00 46.50  ? 258 HIS C O   1 
ATOM   7422  C CB  . HIS C 1 239 ? 43.085  8.973   145.368 1.00 40.76  ? 258 HIS C CB  1 
ATOM   7423  C CG  . HIS C 1 239 ? 41.769  9.670   145.515 1.00 38.72  ? 258 HIS C CG  1 
ATOM   7424  N ND1 . HIS C 1 239 ? 40.601  9.182   144.969 1.00 37.50  ? 258 HIS C ND1 1 
ATOM   7425  C CD2 . HIS C 1 239 ? 41.439  10.828  146.148 1.00 38.65  ? 258 HIS C CD2 1 
ATOM   7426  C CE1 . HIS C 1 239 ? 39.606  10.002  145.265 1.00 36.42  ? 258 HIS C CE1 1 
ATOM   7427  N NE2 . HIS C 1 239 ? 40.093  11.023  145.960 1.00 37.40  ? 258 HIS C NE2 1 
ATOM   7428  N N   . PHE C 1 240 ? 45.968  9.375   145.054 1.00 42.85  ? 259 PHE C N   1 
ATOM   7429  C CA  . PHE C 1 240 ? 47.402  9.129   145.231 1.00 44.90  ? 259 PHE C CA  1 
ATOM   7430  C C   . PHE C 1 240 ? 48.068  9.475   143.903 1.00 46.72  ? 259 PHE C C   1 
ATOM   7431  O O   . PHE C 1 240 ? 47.808  10.554  143.362 1.00 47.73  ? 259 PHE C O   1 
ATOM   7432  C CB  . PHE C 1 240 ? 47.607  7.714   145.735 1.00 44.21  ? 259 PHE C CB  1 
ATOM   7433  C CG  . PHE C 1 240 ? 46.860  7.422   147.006 1.00 41.97  ? 259 PHE C CG  1 
ATOM   7434  C CD1 . PHE C 1 240 ? 47.383  7.781   148.238 1.00 42.44  ? 259 PHE C CD1 1 
ATOM   7435  C CD2 . PHE C 1 240 ? 45.631  6.814   146.969 1.00 39.36  ? 259 PHE C CD2 1 
ATOM   7436  C CE1 . PHE C 1 240 ? 46.701  7.518   149.400 1.00 40.33  ? 259 PHE C CE1 1 
ATOM   7437  C CE2 . PHE C 1 240 ? 44.931  6.552   148.131 1.00 37.24  ? 259 PHE C CE2 1 
ATOM   7438  C CZ  . PHE C 1 240 ? 45.464  6.902   149.345 1.00 37.90  ? 259 PHE C CZ  1 
ATOM   7439  N N   . GLN C 1 241 ? 48.919  8.628   143.344 1.00 43.85  ? 260 GLN C N   1 
ATOM   7440  C CA  . GLN C 1 241 ? 49.547  8.930   142.067 1.00 45.78  ? 260 GLN C CA  1 
ATOM   7441  C C   . GLN C 1 241 ? 48.783  8.342   140.882 1.00 44.40  ? 260 GLN C C   1 
ATOM   7442  O O   . GLN C 1 241 ? 49.345  8.203   139.786 1.00 45.60  ? 260 GLN C O   1 
ATOM   7443  C CB  . GLN C 1 241 ? 50.990  8.443   142.079 1.00 48.68  ? 260 GLN C CB  1 
ATOM   7444  C CG  . GLN C 1 241 ? 51.819  9.144   143.119 1.00 51.47  ? 260 GLN C CG  1 
ATOM   7445  C CD  . GLN C 1 241 ? 53.288  8.794   142.993 1.00 54.94  ? 260 GLN C CD  1 
ATOM   7446  O OE1 . GLN C 1 241 ? 53.723  8.311   141.947 1.00 55.94  ? 260 GLN C OE1 1 
ATOM   7447  N NE2 . GLN C 1 241 ? 54.062  9.010   144.070 1.00 56.85  ? 260 GLN C NE2 1 
ATOM   7448  N N   . SER C 1 242 ? 47.509  8.017   141.080 1.00 44.80  ? 261 SER C N   1 
ATOM   7449  C CA  . SER C 1 242 ? 46.702  7.327   140.087 1.00 43.49  ? 261 SER C CA  1 
ATOM   7450  C C   . SER C 1 242 ? 45.498  8.163   139.692 1.00 42.49  ? 261 SER C C   1 
ATOM   7451  O O   . SER C 1 242 ? 44.563  7.669   139.060 1.00 41.64  ? 261 SER C O   1 
ATOM   7452  C CB  . SER C 1 242 ? 46.277  5.952   140.620 1.00 42.21  ? 261 SER C CB  1 
ATOM   7453  O OG  . SER C 1 242 ? 47.391  5.205   141.136 1.00 43.09  ? 261 SER C OG  1 
ATOM   7454  N N   . ALA C 1 243 ? 45.522  9.445   140.021 1.00 43.23  ? 262 ALA C N   1 
ATOM   7455  C CA  . ALA C 1 243 ? 44.394  10.319  139.720 1.00 42.62  ? 262 ALA C CA  1 
ATOM   7456  C C   . ALA C 1 243 ? 44.349  10.782  138.270 1.00 43.53  ? 262 ALA C C   1 
ATOM   7457  O O   . ALA C 1 243 ? 43.290  11.208  137.815 1.00 43.11  ? 262 ALA C O   1 
ATOM   7458  C CB  . ALA C 1 243 ? 44.423  11.527  140.654 1.00 43.38  ? 262 ALA C CB  1 
ATOM   7459  N N   . SER C 1 244 ? 45.443  10.694  137.524 1.00 42.71  ? 263 SER C N   1 
ATOM   7460  C CA  . SER C 1 244 ? 45.392  11.148  136.137 1.00 43.71  ? 263 SER C CA  1 
ATOM   7461  C C   . SER C 1 244 ? 44.456  10.254  135.323 1.00 42.56  ? 263 SER C C   1 
ATOM   7462  O O   . SER C 1 244 ? 44.176  9.116   135.687 1.00 41.55  ? 263 SER C O   1 
ATOM   7463  C CB  . SER C 1 244 ? 46.793  11.176  135.513 1.00 46.02  ? 263 SER C CB  1 
ATOM   7464  O OG  . SER C 1 244 ? 47.265  9.890   135.159 1.00 46.41  ? 263 SER C OG  1 
ATOM   7465  N N   . LYS C 1 245 ? 43.971  10.794  134.204 1.00 41.97  ? 264 LYS C N   1 
ATOM   7466  C CA  . LYS C 1 245 ? 43.043  10.067  133.349 1.00 41.73  ? 264 LYS C CA  1 
ATOM   7467  C C   . LYS C 1 245 ? 43.693  8.857   132.688 1.00 42.54  ? 264 LYS C C   1 
ATOM   7468  O O   . LYS C 1 245 ? 43.008  7.881   132.380 1.00 41.86  ? 264 LYS C O   1 
ATOM   7469  C CB  . LYS C 1 245 ? 42.497  11.007  132.271 1.00 43.10  ? 264 LYS C CB  1 
ATOM   7470  C CG  . LYS C 1 245 ? 43.527  11.509  131.230 1.00 45.49  ? 264 LYS C CG  1 
ATOM   7471  C CD  . LYS C 1 245 ? 42.935  12.737  130.462 1.00 46.26  ? 264 LYS C CD  1 
ATOM   7472  C CE  . LYS C 1 245 ? 43.819  13.262  129.347 1.00 48.75  ? 264 LYS C CE  1 
ATOM   7473  N NZ  . LYS C 1 245 ? 44.983  13.897  129.951 1.00 49.88  ? 264 LYS C NZ  1 
ATOM   7474  N N   . GLU C 1 246 ? 44.994  8.944   132.411 1.00 42.34  ? 265 GLU C N   1 
ATOM   7475  C CA  . GLU C 1 246 ? 45.742  7.842   131.837 1.00 43.80  ? 265 GLU C CA  1 
ATOM   7476  C C   . GLU C 1 246 ? 45.751  6.666   132.782 1.00 42.43  ? 265 GLU C C   1 
ATOM   7477  O O   . GLU C 1 246 ? 45.434  5.540   132.386 1.00 42.48  ? 265 GLU C O   1 
ATOM   7478  C CB  . GLU C 1 246 ? 47.165  8.301   131.549 1.00 46.42  ? 265 GLU C CB  1 
ATOM   7479  C CG  . GLU C 1 246 ? 47.265  9.309   130.440 1.00 48.09  ? 265 GLU C CG  1 
ATOM   7480  C CD  . GLU C 1 246 ? 47.193  10.773  130.915 1.00 47.79  ? 265 GLU C CD  1 
ATOM   7481  O OE1 . GLU C 1 246 ? 47.209  11.687  130.028 1.00 48.96  ? 265 GLU C OE1 1 
ATOM   7482  O OE2 . GLU C 1 246 ? 47.115  11.029  132.154 1.00 46.60  ? 265 GLU C OE2 1 
ATOM   7483  N N   . THR C 1 247 ? 46.102  6.919   134.049 1.00 43.98  ? 266 THR C N   1 
ATOM   7484  C CA  . THR C 1 247 ? 46.161  5.841   135.028 1.00 43.09  ? 266 THR C CA  1 
ATOM   7485  C C   . THR C 1 247 ? 44.767  5.324   135.364 1.00 40.60  ? 266 THR C C   1 
ATOM   7486  O O   . THR C 1 247 ? 44.587  4.125   135.593 1.00 40.25  ? 266 THR C O   1 
ATOM   7487  C CB  . THR C 1 247 ? 46.897  6.293   136.296 1.00 43.80  ? 266 THR C CB  1 
ATOM   7488  O OG1 . THR C 1 247 ? 46.275  7.440   136.864 1.00 42.71  ? 266 THR C OG1 1 
ATOM   7489  C CG2 . THR C 1 247 ? 48.329  6.657   135.995 1.00 46.69  ? 266 THR C CG2 1 
ATOM   7490  N N   . MET C 1 248 ? 43.771  6.207   135.361 1.00 43.09  ? 267 MET C N   1 
ATOM   7491  C CA  . MET C 1 248 ? 42.409  5.786   135.656 1.00 41.33  ? 267 MET C CA  1 
ATOM   7492  C C   . MET C 1 248 ? 41.887  4.845   134.581 1.00 41.85  ? 267 MET C C   1 
ATOM   7493  O O   . MET C 1 248 ? 41.214  3.854   134.885 1.00 41.00  ? 267 MET C O   1 
ATOM   7494  C CB  . MET C 1 248 ? 41.524  7.011   135.757 1.00 40.82  ? 267 MET C CB  1 
ATOM   7495  C CG  . MET C 1 248 ? 41.828  7.868   136.958 1.00 40.74  ? 267 MET C CG  1 
ATOM   7496  S SD  . MET C 1 248 ? 40.298  8.572   137.579 1.00 39.78  ? 267 MET C SD  1 
ATOM   7497  C CE  . MET C 1 248 ? 40.135  9.998   136.593 1.00 40.92  ? 267 MET C CE  1 
ATOM   7498  N N   . LEU C 1 249 ? 42.182  5.163   133.318 1.00 40.85  ? 268 LEU C N   1 
ATOM   7499  C CA  . LEU C 1 249 ? 41.796  4.290   132.232 1.00 41.88  ? 268 LEU C CA  1 
ATOM   7500  C C   . LEU C 1 249 ? 42.550  2.977   132.315 1.00 42.22  ? 268 LEU C C   1 
ATOM   7501  O O   . LEU C 1 249 ? 41.941  1.930   132.141 1.00 42.13  ? 268 LEU C O   1 
ATOM   7502  C CB  . LEU C 1 249 ? 42.026  5.002   130.907 1.00 43.79  ? 268 LEU C CB  1 
ATOM   7503  C CG  . LEU C 1 249 ? 41.715  4.186   129.661 1.00 44.97  ? 268 LEU C CG  1 
ATOM   7504  C CD1 . LEU C 1 249 ? 40.293  3.699   129.686 1.00 43.57  ? 268 LEU C CD1 1 
ATOM   7505  C CD2 . LEU C 1 249 ? 41.963  4.971   128.373 1.00 47.14  ? 268 LEU C CD2 1 
ATOM   7506  N N   . ARG C 1 250 ? 43.854  2.999   132.628 1.00 41.66  ? 269 ARG C N   1 
ATOM   7507  C CA  . ARG C 1 250 ? 44.604  1.747   132.765 1.00 42.41  ? 269 ARG C CA  1 
ATOM   7508  C C   . ARG C 1 250 ? 44.034  0.870   133.886 1.00 40.65  ? 269 ARG C C   1 
ATOM   7509  O O   . ARG C 1 250 ? 43.834  -0.325  133.683 1.00 40.91  ? 269 ARG C O   1 
ATOM   7510  C CB  . ARG C 1 250 ? 46.102  2.002   132.987 1.00 44.27  ? 269 ARG C CB  1 
ATOM   7511  N N   . ASP C 1 251 ? 43.715  1.438   135.054 1.00 43.99  ? 270 ASP C N   1 
ATOM   7512  C CA  . ASP C 1 251 ? 43.093  0.634   136.101 1.00 42.28  ? 270 ASP C CA  1 
ATOM   7513  C C   . ASP C 1 251 ? 41.757  0.044   135.633 1.00 41.52  ? 270 ASP C C   1 
ATOM   7514  O O   . ASP C 1 251 ? 41.462  -1.117  135.913 1.00 41.16  ? 270 ASP C O   1 
ATOM   7515  C CB  . ASP C 1 251 ? 42.889  1.458   137.386 1.00 41.43  ? 270 ASP C CB  1 
ATOM   7516  C CG  . ASP C 1 251 ? 44.232  1.738   138.158 1.00 42.39  ? 270 ASP C CG  1 
ATOM   7517  O OD1 . ASP C 1 251 ? 45.226  1.051   137.826 1.00 42.47  ? 270 ASP C OD1 1 
ATOM   7518  O OD2 . ASP C 1 251 ? 44.317  2.585   139.126 1.00 43.72  ? 270 ASP C OD2 1 
ATOM   7519  N N   . ILE C 1 252 ? 40.934  0.814   134.915 1.00 41.12  ? 271 ILE C N   1 
ATOM   7520  C CA  . ILE C 1 252 ? 39.573  0.364   134.620 1.00 40.86  ? 271 ILE C CA  1 
ATOM   7521  C C   . ILE C 1 252 ? 39.611  -0.737  133.579 1.00 42.84  ? 271 ILE C C   1 
ATOM   7522  O O   . ILE C 1 252 ? 38.793  -1.668  133.594 1.00 42.86  ? 271 ILE C O   1 
ATOM   7523  C CB  . ILE C 1 252 ? 38.703  1.512   134.115 1.00 40.69  ? 271 ILE C CB  1 
ATOM   7524  C CG1 . ILE C 1 252 ? 38.268  2.446   135.246 1.00 39.63  ? 271 ILE C CG1 1 
ATOM   7525  C CG2 . ILE C 1 252 ? 37.449  1.003   133.422 1.00 40.86  ? 271 ILE C CG2 1 
ATOM   7526  C CD1 . ILE C 1 252 ? 37.758  3.870   134.719 1.00 40.16  ? 271 ILE C CD1 1 
ATOM   7527  N N   . LEU C 1 253 ? 40.551  -0.650  132.656 1.00 41.17  ? 272 LEU C N   1 
ATOM   7528  C CA  . LEU C 1 253 ? 40.628  -1.660  131.629 1.00 42.75  ? 272 LEU C CA  1 
ATOM   7529  C C   . LEU C 1 253 ? 41.198  -2.940  132.202 1.00 43.04  ? 272 LEU C C   1 
ATOM   7530  O O   . LEU C 1 253 ? 40.761  -4.032  131.837 1.00 43.36  ? 272 LEU C O   1 
ATOM   7531  C CB  . LEU C 1 253 ? 41.461  -1.144  130.472 1.00 44.86  ? 272 LEU C CB  1 
ATOM   7532  C CG  . LEU C 1 253 ? 40.718  -0.101  129.627 1.00 44.98  ? 272 LEU C CG  1 
ATOM   7533  C CD1 . LEU C 1 253 ? 41.683  0.475   128.597 1.00 47.05  ? 272 LEU C CD1 1 
ATOM   7534  C CD2 . LEU C 1 253 ? 39.437  -0.659  128.966 1.00 44.89  ? 272 LEU C CD2 1 
ATOM   7535  N N   . GLU C 1 254 ? 42.169  -2.836  133.096 1.00 43.74  ? 273 GLU C N   1 
ATOM   7536  C CA  . GLU C 1 254 ? 42.695  -4.045  133.699 1.00 43.54  ? 273 GLU C CA  1 
ATOM   7537  C C   . GLU C 1 254 ? 41.607  -4.742  134.501 1.00 41.81  ? 273 GLU C C   1 
ATOM   7538  O O   . GLU C 1 254 ? 41.493  -5.975  134.479 1.00 42.00  ? 273 GLU C O   1 
ATOM   7539  C CB  . GLU C 1 254 ? 43.899  -3.726  134.563 1.00 43.67  ? 273 GLU C CB  1 
ATOM   7540  C CG  . GLU C 1 254 ? 44.519  -4.955  135.218 1.00 43.81  ? 273 GLU C CG  1 
ATOM   7541  C CD  . GLU C 1 254 ? 45.075  -5.958  134.219 1.00 45.99  ? 273 GLU C CD  1 
ATOM   7542  O OE1 . GLU C 1 254 ? 45.112  -5.659  133.022 1.00 47.32  ? 273 GLU C OE1 1 
ATOM   7543  O OE2 . GLU C 1 254 ? 45.478  -7.065  134.640 1.00 46.40  ? 273 GLU C OE2 1 
ATOM   7544  N N   . MET C 1 255 ? 40.770  -3.968  135.184 1.00 44.82  ? 274 MET C N   1 
ATOM   7545  C CA  . MET C 1 255 ? 39.649  -4.590  135.856 1.00 43.82  ? 274 MET C CA  1 
ATOM   7546  C C   . MET C 1 255 ? 38.828  -5.367  134.852 1.00 44.94  ? 274 MET C C   1 
ATOM   7547  O O   . MET C 1 255 ? 38.524  -6.544  135.059 1.00 45.01  ? 274 MET C O   1 
ATOM   7548  C CB  . MET C 1 255 ? 38.761  -3.562  136.549 1.00 42.49  ? 274 MET C CB  1 
ATOM   7549  C CG  . MET C 1 255 ? 37.488  -4.213  137.068 1.00 41.78  ? 274 MET C CG  1 
ATOM   7550  S SD  . MET C 1 255 ? 36.372  -3.279  138.159 1.00 40.45  ? 274 MET C SD  1 
ATOM   7551  C CE  . MET C 1 255 ? 35.928  -1.861  137.105 1.00 40.71  ? 274 MET C CE  1 
ATOM   7552  N N   . GLN C 1 256 ? 38.440  -4.710  133.760 1.00 41.19  ? 275 GLN C N   1 
ATOM   7553  C CA  . GLN C 1 256 ? 37.602  -5.369  132.763 1.00 42.06  ? 275 GLN C CA  1 
ATOM   7554  C C   . GLN C 1 256 ? 38.245  -6.665  132.267 1.00 43.23  ? 275 GLN C C   1 
ATOM   7555  O O   . GLN C 1 256 ? 37.579  -7.704  132.151 1.00 43.47  ? 275 GLN C O   1 
ATOM   7556  C CB  . GLN C 1 256 ? 37.347  -4.414  131.604 1.00 43.01  ? 275 GLN C CB  1 
ATOM   7557  C CG  . GLN C 1 256 ? 36.616  -5.057  130.467 1.00 43.74  ? 275 GLN C CG  1 
ATOM   7558  C CD  . GLN C 1 256 ? 36.420  -4.089  129.306 1.00 44.78  ? 275 GLN C CD  1 
ATOM   7559  O OE1 . GLN C 1 256 ? 35.295  -3.888  128.800 1.00 44.70  ? 275 GLN C OE1 1 
ATOM   7560  N NE2 . GLN C 1 256 ? 37.514  -3.496  128.866 1.00 45.58  ? 275 GLN C NE2 1 
ATOM   7561  N N   . ARG C 1 257 ? 39.540  -6.607  131.936 1.00 40.39  ? 276 ARG C N   1 
ATOM   7562  C CA  . ARG C 1 257 ? 40.218  -7.735  131.309 1.00 41.50  ? 276 ARG C CA  1 
ATOM   7563  C C   . ARG C 1 257 ? 40.377  -8.886  132.286 1.00 40.64  ? 276 ARG C C   1 
ATOM   7564  O O   . ARG C 1 257 ? 39.982  -10.006 131.993 1.00 41.73  ? 276 ARG C O   1 
ATOM   7565  C CB  . ARG C 1 257 ? 41.569  -7.267  130.804 1.00 42.70  ? 276 ARG C CB  1 
ATOM   7566  C CG  . ARG C 1 257 ? 42.351  -8.256  130.032 1.00 44.23  ? 276 ARG C CG  1 
ATOM   7567  C CD  . ARG C 1 257 ? 43.829  -7.907  130.090 1.00 45.21  ? 276 ARG C CD  1 
ATOM   7568  N NE  . ARG C 1 257 ? 44.386  -8.173  131.417 1.00 44.28  ? 276 ARG C NE  1 
ATOM   7569  C CZ  . ARG C 1 257 ? 44.580  -9.392  131.921 1.00 44.03  ? 276 ARG C CZ  1 
ATOM   7570  N NH1 . ARG C 1 257 ? 44.402  -10.478 131.194 1.00 45.13  ? 276 ARG C NH1 1 
ATOM   7571  N NH2 . ARG C 1 257 ? 44.977  -9.518  133.188 1.00 43.27  ? 276 ARG C NH2 1 
ATOM   7572  N N   . ALA C 1 258 ? 40.927  -8.620  133.477 1.00 42.31  ? 277 ALA C N   1 
ATOM   7573  C CA  . ALA C 1 258 ? 41.159  -9.692  134.430 1.00 41.68  ? 277 ALA C CA  1 
ATOM   7574  C C   . ALA C 1 258 ? 39.844  -10.335 134.850 1.00 40.60  ? 277 ALA C C   1 
ATOM   7575  O O   . ALA C 1 258 ? 39.763  -11.576 134.969 1.00 40.96  ? 277 ALA C O   1 
ATOM   7576  C CB  . ALA C 1 258 ? 41.945  -9.176  135.640 1.00 40.91  ? 277 ALA C CB  1 
ATOM   7577  N N   . ALA C 1 259 ? 38.786  -9.526  135.035 1.00 40.45  ? 278 ALA C N   1 
ATOM   7578  C CA  . ALA C 1 259 ? 37.502  -10.147 135.354 1.00 40.41  ? 278 ALA C CA  1 
ATOM   7579  C C   . ALA C 1 259 ? 36.989  -10.973 134.170 1.00 42.03  ? 278 ALA C C   1 
ATOM   7580  O O   . ALA C 1 259 ? 36.560  -12.127 134.329 1.00 42.58  ? 278 ALA C O   1 
ATOM   7581  C CB  . ALA C 1 259 ? 36.472  -9.115  135.763 1.00 39.86  ? 278 ALA C CB  1 
ATOM   7582  N N   . LYS C 1 260 ? 37.067  -10.421 132.963 1.00 41.36  ? 279 LYS C N   1 
ATOM   7583  C CA  . LYS C 1 260 ? 36.656  -11.185 131.787 1.00 42.89  ? 279 LYS C CA  1 
ATOM   7584  C C   . LYS C 1 260 ? 37.456  -12.463 131.633 1.00 44.07  ? 279 LYS C C   1 
ATOM   7585  O O   . LYS C 1 260 ? 37.018  -13.363 130.918 1.00 46.52  ? 279 LYS C O   1 
ATOM   7586  C CB  . LYS C 1 260 ? 36.807  -10.330 130.532 1.00 44.63  ? 279 LYS C CB  1 
ATOM   7587  C CG  . LYS C 1 260 ? 35.550  -9.533  130.180 1.00 45.19  ? 279 LYS C CG  1 
ATOM   7588  C CD  . LYS C 1 260 ? 35.814  -8.618  128.981 1.00 46.79  ? 279 LYS C CD  1 
ATOM   7589  C CE  . LYS C 1 260 ? 34.564  -7.845  128.529 1.00 47.35  ? 279 LYS C CE  1 
ATOM   7590  N NZ  . LYS C 1 260 ? 33.274  -8.567  128.770 1.00 47.95  ? 279 LYS C NZ  1 
ATOM   7591  N N   . ALA C 1 261 ? 38.614  -12.552 132.282 1.00 42.66  ? 280 ALA C N   1 
ATOM   7592  C CA  . ALA C 1 261 ? 39.438  -13.747 132.313 1.00 44.31  ? 280 ALA C CA  1 
ATOM   7593  C C   . ALA C 1 261 ? 39.147  -14.618 133.512 1.00 43.60  ? 280 ALA C C   1 
ATOM   7594  O O   . ALA C 1 261 ? 39.906  -15.537 133.777 1.00 44.77  ? 280 ALA C O   1 
ATOM   7595  C CB  . ALA C 1 261 ? 40.928  -13.391 132.319 1.00 43.46  ? 280 ALA C CB  1 
ATOM   7596  N N   . GLY C 1 262 ? 38.090  -14.333 134.261 1.00 43.79  ? 281 GLY C N   1 
ATOM   7597  C CA  . GLY C 1 262 ? 37.690  -15.179 135.367 1.00 43.15  ? 281 GLY C CA  1 
ATOM   7598  C C   . GLY C 1 262 ? 38.182  -14.789 136.754 1.00 41.84  ? 281 GLY C C   1 
ATOM   7599  O O   . GLY C 1 262 ? 37.896  -15.519 137.722 1.00 41.48  ? 281 GLY C O   1 
ATOM   7600  N N   . LYS C 1 263 ? 38.898  -13.674 136.898 1.00 42.57  ? 282 LYS C N   1 
ATOM   7601  C CA  . LYS C 1 263 ? 39.425  -13.309 138.207 1.00 41.38  ? 282 LYS C CA  1 
ATOM   7602  C C   . LYS C 1 263 ? 38.461  -12.387 138.948 1.00 40.30  ? 282 LYS C C   1 
ATOM   7603  O O   . LYS C 1 263 ? 37.480  -11.877 138.398 1.00 40.60  ? 282 LYS C O   1 
ATOM   7604  C CB  . LYS C 1 263 ? 40.800  -12.653 138.074 1.00 41.91  ? 282 LYS C CB  1 
ATOM   7605  C CG  . LYS C 1 263 ? 41.884  -13.619 137.591 1.00 43.87  ? 282 LYS C CG  1 
ATOM   7606  C CD  . LYS C 1 263 ? 42.018  -14.841 138.530 1.00 43.78  ? 282 LYS C CD  1 
ATOM   7607  C CE  . LYS C 1 263 ? 43.278  -15.590 138.235 1.00 45.21  ? 282 LYS C CE  1 
ATOM   7608  N NZ  . LYS C 1 263 ? 43.367  -16.878 138.997 1.00 45.74  ? 282 LYS C NZ  1 
ATOM   7609  N N   . ILE C 1 264 ? 38.731  -12.227 140.212 1.00 40.26  ? 283 ILE C N   1 
ATOM   7610  C CA  . ILE C 1 264 ? 38.052  -11.257 141.055 1.00 39.09  ? 283 ILE C CA  1 
ATOM   7611  C C   . ILE C 1 264 ? 38.855  -9.970  141.012 1.00 38.64  ? 283 ILE C C   1 
ATOM   7612  O O   . ILE C 1 264 ? 40.090  -9.994  140.990 1.00 39.41  ? 283 ILE C O   1 
ATOM   7613  C CB  . ILE C 1 264 ? 37.907  -11.781 142.492 1.00 38.55  ? 283 ILE C CB  1 
ATOM   7614  C CG1 . ILE C 1 264 ? 36.933  -12.947 142.509 1.00 39.11  ? 283 ILE C CG1 1 
ATOM   7615  C CG2 . ILE C 1 264 ? 37.400  -10.685 143.407 1.00 37.73  ? 283 ILE C CG2 1 
ATOM   7616  C CD1 . ILE C 1 264 ? 37.034  -13.778 143.706 1.00 39.29  ? 283 ILE C CD1 1 
ATOM   7617  N N   . VAL C 1 265 ? 38.155  -8.841  140.973 1.00 39.02  ? 284 VAL C N   1 
ATOM   7618  C CA  . VAL C 1 265 ? 38.774  -7.522  141.022 1.00 38.82  ? 284 VAL C CA  1 
ATOM   7619  C C   . VAL C 1 265 ? 38.017  -6.704  142.044 1.00 37.93  ? 284 VAL C C   1 
ATOM   7620  O O   . VAL C 1 265 ? 36.798  -6.528  141.918 1.00 37.41  ? 284 VAL C O   1 
ATOM   7621  C CB  . VAL C 1 265 ? 38.731  -6.822  139.664 1.00 39.84  ? 284 VAL C CB  1 
ATOM   7622  C CG1 . VAL C 1 265 ? 39.328  -5.477  139.765 1.00 39.75  ? 284 VAL C CG1 1 
ATOM   7623  C CG2 . VAL C 1 265 ? 39.456  -7.639  138.628 1.00 41.46  ? 284 VAL C CG2 1 
ATOM   7624  N N   . VAL C 1 266 ? 38.719  -6.191  143.038 1.00 37.82  ? 285 VAL C N   1 
ATOM   7625  C CA  . VAL C 1 266 ? 38.109  -5.290  144.008 1.00 37.06  ? 285 VAL C CA  1 
ATOM   7626  C C   . VAL C 1 266 ? 38.641  -3.892  143.750 1.00 37.26  ? 285 VAL C C   1 
ATOM   7627  O O   . VAL C 1 266 ? 39.853  -3.671  143.779 1.00 38.03  ? 285 VAL C O   1 
ATOM   7628  C CB  . VAL C 1 266 ? 38.385  -5.710  145.454 1.00 37.01  ? 285 VAL C CB  1 
ATOM   7629  C CG1 . VAL C 1 266 ? 37.647  -4.773  146.373 1.00 36.58  ? 285 VAL C CG1 1 
ATOM   7630  C CG2 . VAL C 1 266 ? 37.992  -7.159  145.703 1.00 36.98  ? 285 VAL C CG2 1 
ATOM   7631  N N   . LEU C 1 267 ? 37.747  -2.951  143.522 1.00 35.96  ? 286 LEU C N   1 
ATOM   7632  C CA  . LEU C 1 267 ? 38.107  -1.576  143.214 1.00 36.33  ? 286 LEU C CA  1 
ATOM   7633  C C   . LEU C 1 267 ? 37.821  -0.699  144.436 1.00 36.22  ? 286 LEU C C   1 
ATOM   7634  O O   . LEU C 1 267 ? 36.690  -0.661  144.941 1.00 35.78  ? 286 LEU C O   1 
ATOM   7635  C CB  . LEU C 1 267 ? 37.331  -1.070  141.992 1.00 36.36  ? 286 LEU C CB  1 
ATOM   7636  C CG  . LEU C 1 267 ? 37.741  0.314   141.481 1.00 37.06  ? 286 LEU C CG  1 
ATOM   7637  C CD1 . LEU C 1 267 ? 37.634  0.372   139.956 1.00 37.83  ? 286 LEU C CD1 1 
ATOM   7638  C CD2 . LEU C 1 267 ? 36.890  1.435   142.044 1.00 37.11  ? 286 LEU C CD2 1 
ATOM   7639  N N   . LYS C 1 268 ? 38.850  -0.011  144.918 1.00 36.53  ? 287 LYS C N   1 
ATOM   7640  C CA  . LYS C 1 268 ? 38.726  0.864   146.079 1.00 37.06  ? 287 LYS C CA  1 
ATOM   7641  C C   . LYS C 1 268 ? 38.381  2.266   145.593 1.00 38.23  ? 287 LYS C C   1 
ATOM   7642  O O   . LYS C 1 268 ? 39.230  2.956   145.025 1.00 39.00  ? 287 LYS C O   1 
ATOM   7643  C CB  . LYS C 1 268 ? 40.020  0.857   146.891 1.00 38.09  ? 287 LYS C CB  1 
ATOM   7644  C CG  . LYS C 1 268 ? 39.996  1.760   148.111 1.00 40.34  ? 287 LYS C CG  1 
ATOM   7645  C CD  . LYS C 1 268 ? 39.088  1.186   149.201 1.00 38.44  ? 287 LYS C CD  1 
ATOM   7646  C CE  . LYS C 1 268 ? 39.253  1.922   150.548 1.00 40.03  ? 287 LYS C CE  1 
ATOM   7647  N NZ  . LYS C 1 268 ? 38.444  3.159   150.559 1.00 39.46  ? 287 LYS C NZ  1 
ATOM   7648  N N   . GLY C 1 269 ? 37.127  2.677   145.783 1.00 37.46  ? 288 GLY C N   1 
ATOM   7649  C CA  . GLY C 1 269 ? 36.798  4.092   145.694 1.00 38.05  ? 288 GLY C CA  1 
ATOM   7650  C C   . GLY C 1 269 ? 37.155  4.858   146.961 1.00 38.98  ? 288 GLY C C   1 
ATOM   7651  O O   . GLY C 1 269 ? 37.160  4.328   148.075 1.00 39.41  ? 288 GLY C O   1 
ATOM   7652  N N   . TRP C 1 270 ? 37.474  6.132   146.795 1.00 37.49  ? 289 TRP C N   1 
ATOM   7653  C CA  . TRP C 1 270 ? 37.774  7.014   147.916 1.00 38.22  ? 289 TRP C CA  1 
ATOM   7654  C C   . TRP C 1 270 ? 36.714  8.099   147.958 1.00 38.65  ? 289 TRP C C   1 
ATOM   7655  O O   . TRP C 1 270 ? 36.348  8.647   146.909 1.00 38.66  ? 289 TRP C O   1 
ATOM   7656  C CB  . TRP C 1 270 ? 39.187  7.562   147.757 1.00 38.39  ? 289 TRP C CB  1 
ATOM   7657  C CG  . TRP C 1 270 ? 40.233  6.468   147.922 1.00 38.14  ? 289 TRP C CG  1 
ATOM   7658  C CD1 . TRP C 1 270 ? 40.830  5.735   146.929 1.00 37.77  ? 289 TRP C CD1 1 
ATOM   7659  C CD2 . TRP C 1 270 ? 40.764  5.961   149.164 1.00 38.43  ? 289 TRP C CD2 1 
ATOM   7660  N NE1 . TRP C 1 270 ? 41.694  4.811   147.480 1.00 38.58  ? 289 TRP C NE1 1 
ATOM   7661  C CE2 . TRP C 1 270 ? 41.667  4.929   148.844 1.00 38.82  ? 289 TRP C CE2 1 
ATOM   7662  C CE3 . TRP C 1 270 ? 40.555  6.277   150.503 1.00 38.98  ? 289 TRP C CE3 1 
ATOM   7663  C CZ2 . TRP C 1 270 ? 42.381  4.239   149.813 1.00 39.39  ? 289 TRP C CZ2 1 
ATOM   7664  C CZ3 . TRP C 1 270 ? 41.277  5.573   151.479 1.00 39.42  ? 289 TRP C CZ3 1 
ATOM   7665  C CH2 . TRP C 1 270 ? 42.175  4.575   151.122 1.00 39.53  ? 289 TRP C CH2 1 
ATOM   7666  N N   . ALA C 1 271 ? 36.197  8.379   149.151 1.00 36.83  ? 290 ALA C N   1 
ATOM   7667  C CA  . ALA C 1 271 ? 35.043  9.289   149.287 1.00 38.13  ? 290 ALA C CA  1 
ATOM   7668  C C   . ALA C 1 271 ? 35.463  10.756  149.340 1.00 38.16  ? 290 ALA C C   1 
ATOM   7669  O O   . ALA C 1 271 ? 35.108  11.500  150.250 1.00 39.23  ? 290 ALA C O   1 
ATOM   7670  C CB  . ALA C 1 271 ? 34.205  8.930   150.500 1.00 39.96  ? 290 ALA C CB  1 
ATOM   7671  N N   . GLY C 1 272 ? 36.216  11.166  148.327 1.00 38.35  ? 291 GLY C N   1 
ATOM   7672  C CA  . GLY C 1 272 ? 36.633  12.532  148.171 1.00 38.56  ? 291 GLY C CA  1 
ATOM   7673  C C   . GLY C 1 272 ? 37.932  12.880  148.852 1.00 38.66  ? 291 GLY C C   1 
ATOM   7674  O O   . GLY C 1 272 ? 38.464  13.976  148.643 1.00 39.41  ? 291 GLY C O   1 
ATOM   7675  N N   . PHE C 1 273 ? 38.472  11.999  149.654 1.00 38.56  ? 292 PHE C N   1 
ATOM   7676  C CA  . PHE C 1 273 ? 39.679  12.353  150.377 1.00 38.74  ? 292 PHE C CA  1 
ATOM   7677  C C   . PHE C 1 273 ? 40.158  11.045  150.965 1.00 38.58  ? 292 PHE C C   1 
ATOM   7678  O O   . PHE C 1 273 ? 39.427  10.059  150.953 1.00 38.24  ? 292 PHE C O   1 
ATOM   7679  C CB  . PHE C 1 273 ? 39.419  13.439  151.429 1.00 39.49  ? 292 PHE C CB  1 
ATOM   7680  C CG  . PHE C 1 273 ? 38.419  13.044  152.463 1.00 39.92  ? 292 PHE C CG  1 
ATOM   7681  C CD1 . PHE C 1 273 ? 37.080  13.123  152.209 1.00 40.15  ? 292 PHE C CD1 1 
ATOM   7682  C CD2 . PHE C 1 273 ? 38.823  12.571  153.708 1.00 40.32  ? 292 PHE C CD2 1 
ATOM   7683  C CE1 . PHE C 1 273 ? 36.148  12.745  153.188 1.00 41.35  ? 292 PHE C CE1 1 
ATOM   7684  C CE2 . PHE C 1 273 ? 37.893  12.203  154.696 1.00 41.24  ? 292 PHE C CE2 1 
ATOM   7685  C CZ  . PHE C 1 273 ? 36.569  12.278  154.434 1.00 41.83  ? 292 PHE C CZ  1 
ATOM   7686  N N   . THR C 1 274 ? 41.393  11.040  151.443 1.00 41.67  ? 293 THR C N   1 
ATOM   7687  C CA  . THR C 1 274 ? 41.968  9.841   152.021 1.00 41.91  ? 293 THR C CA  1 
ATOM   7688  C C   . THR C 1 274 ? 42.357  10.099  153.470 1.00 42.57  ? 293 THR C C   1 
ATOM   7689  O O   . THR C 1 274 ? 42.441  11.247  153.952 1.00 43.05  ? 293 THR C O   1 
ATOM   7690  C CB  . THR C 1 274 ? 43.193  9.348   151.239 1.00 42.29  ? 293 THR C CB  1 
ATOM   7691  O OG1 . THR C 1 274 ? 44.320  10.199  151.488 1.00 43.27  ? 293 THR C OG1 1 
ATOM   7692  C CG2 . THR C 1 274 ? 42.904  9.314   149.752 1.00 41.78  ? 293 THR C CG2 1 
ATOM   7693  N N   . PHE C 1 275 ? 42.618  8.980   154.160 1.00 44.17  ? 294 PHE C N   1 
ATOM   7694  C CA  . PHE C 1 275 ? 43.010  9.041   155.563 1.00 45.06  ? 294 PHE C CA  1 
ATOM   7695  C C   . PHE C 1 275 ? 44.351  9.723   155.756 1.00 45.86  ? 294 PHE C C   1 
ATOM   7696  O O   . PHE C 1 275 ? 44.697  10.018  156.896 1.00 47.19  ? 294 PHE C O   1 
ATOM   7697  C CB  . PHE C 1 275 ? 43.032  7.620   156.158 1.00 45.37  ? 294 PHE C CB  1 
ATOM   7698  C CG  . PHE C 1 275 ? 44.105  6.732   155.595 1.00 45.53  ? 294 PHE C CG  1 
ATOM   7699  C CD1 . PHE C 1 275 ? 43.892  6.020   154.428 1.00 45.19  ? 294 PHE C CD1 1 
ATOM   7700  C CD2 . PHE C 1 275 ? 45.321  6.585   156.256 1.00 46.97  ? 294 PHE C CD2 1 
ATOM   7701  C CE1 . PHE C 1 275 ? 44.869  5.190   153.900 1.00 45.62  ? 294 PHE C CE1 1 
ATOM   7702  C CE2 . PHE C 1 275 ? 46.308  5.756   155.730 1.00 47.57  ? 294 PHE C CE2 1 
ATOM   7703  C CZ  . PHE C 1 275 ? 46.074  5.057   154.546 1.00 46.94  ? 294 PHE C CZ  1 
ATOM   7704  N N   . ILE C 1 276 ? 45.103  9.986   154.680 1.00 45.97  ? 295 ILE C N   1 
ATOM   7705  C CA  . ILE C 1 276 ? 46.385  10.668  154.811 1.00 47.21  ? 295 ILE C CA  1 
ATOM   7706  C C   . ILE C 1 276 ? 46.338  12.159  154.477 1.00 47.15  ? 295 ILE C C   1 
ATOM   7707  O O   . ILE C 1 276 ? 47.342  12.868  154.723 1.00 48.60  ? 295 ILE C O   1 
ATOM   7708  C CB  . ILE C 1 276 ? 47.460  9.981   153.953 1.00 48.29  ? 295 ILE C CB  1 
ATOM   7709  C CG1 . ILE C 1 276 ? 47.119  10.040  152.474 1.00 47.79  ? 295 ILE C CG1 1 
ATOM   7710  C CG2 . ILE C 1 276 ? 47.541  8.523   154.307 1.00 48.27  ? 295 ILE C CG2 1 
ATOM   7711  C CD1 . ILE C 1 276 ? 48.246  9.530   151.557 1.00 49.27  ? 295 ILE C CD1 1 
ATOM   7712  N N   . ASP C 1 277 ? 45.203  12.668  153.965 1.00 47.58  ? 296 ASP C N   1 
ATOM   7713  C CA  . ASP C 1 277 ? 45.017  14.115  153.807 1.00 47.99  ? 296 ASP C CA  1 
ATOM   7714  C C   . ASP C 1 277 ? 44.744  14.739  155.168 1.00 48.47  ? 296 ASP C C   1 
ATOM   7715  O O   . ASP C 1 277 ? 43.625  14.606  155.688 1.00 48.21  ? 296 ASP C O   1 
ATOM   7716  C CB  . ASP C 1 277 ? 43.861  14.432  152.865 1.00 47.10  ? 296 ASP C CB  1 
ATOM   7717  C CG  . ASP C 1 277 ? 43.879  13.582  151.622 1.00 46.40  ? 296 ASP C CG  1 
ATOM   7718  O OD1 . ASP C 1 277 ? 44.996  13.199  151.198 1.00 47.18  ? 296 ASP C OD1 1 
ATOM   7719  O OD2 . ASP C 1 277 ? 42.770  13.286  151.078 1.00 45.56  ? 296 ASP C OD2 1 
ATOM   7720  N N   . ASP C 1 278 ? 45.748  15.423  155.741 1.00 48.54  ? 297 ASP C N   1 
ATOM   7721  C CA  . ASP C 1 278 ? 45.611  15.924  157.108 1.00 49.51  ? 297 ASP C CA  1 
ATOM   7722  C C   . ASP C 1 278 ? 44.483  16.940  157.205 1.00 49.40  ? 297 ASP C C   1 
ATOM   7723  O O   . ASP C 1 278 ? 43.671  16.883  158.139 1.00 49.70  ? 297 ASP C O   1 
ATOM   7724  C CB  . ASP C 1 278 ? 46.935  16.515  157.602 1.00 51.45  ? 297 ASP C CB  1 
ATOM   7725  N N   . GLN C 1 279 ? 44.390  17.860  156.236 1.00 49.29  ? 298 GLN C N   1 
ATOM   7726  C CA  . GLN C 1 279 ? 43.351  18.889  156.314 1.00 49.52  ? 298 GLN C CA  1 
ATOM   7727  C C   . GLN C 1 279 ? 41.974  18.245  156.279 1.00 48.39  ? 298 GLN C C   1 
ATOM   7728  O O   . GLN C 1 279 ? 41.123  18.497  157.147 1.00 49.17  ? 298 GLN C O   1 
ATOM   7729  C CB  . GLN C 1 279 ? 43.497  19.904  155.177 1.00 49.64  ? 298 GLN C CB  1 
ATOM   7730  N N   . ALA C 1 280 ? 41.759  17.356  155.301 1.00 47.80  ? 299 ALA C N   1 
ATOM   7731  C CA  . ALA C 1 280 ? 40.463  16.726  155.161 1.00 47.24  ? 299 ALA C CA  1 
ATOM   7732  C C   . ALA C 1 280 ? 40.084  15.925  156.395 1.00 47.52  ? 299 ALA C C   1 
ATOM   7733  O O   . ALA C 1 280 ? 38.896  15.841  156.737 1.00 47.94  ? 299 ALA C O   1 
ATOM   7734  C CB  . ALA C 1 280 ? 40.480  15.844  153.930 1.00 45.97  ? 299 ALA C CB  1 
ATOM   7735  N N   . MET C 1 281 ? 41.055  15.318  157.079 1.00 48.23  ? 300 MET C N   1 
ATOM   7736  C CA  . MET C 1 281 ? 40.690  14.508  158.242 1.00 49.13  ? 300 MET C CA  1 
ATOM   7737  C C   . MET C 1 281 ? 40.318  15.379  159.449 1.00 50.33  ? 300 MET C C   1 
ATOM   7738  O O   . MET C 1 281 ? 39.481  14.966  160.251 1.00 51.52  ? 300 MET C O   1 
ATOM   7739  C CB  . MET C 1 281 ? 41.815  13.545  158.611 1.00 49.00  ? 300 MET C CB  1 
ATOM   7740  C CG  . MET C 1 281 ? 42.008  12.412  157.616 1.00 48.02  ? 300 MET C CG  1 
ATOM   7741  S SD  . MET C 1 281 ? 40.613  11.267  157.299 1.00 47.70  ? 300 MET C SD  1 
ATOM   7742  C CE  . MET C 1 281 ? 40.473  10.296  158.803 1.00 49.09  ? 300 MET C CE  1 
ATOM   7743  N N   . ARG C 1 282 ? 40.881  16.591  159.588 1.00 47.15  ? 301 ARG C N   1 
ATOM   7744  C CA  . ARG C 1 282 ? 40.556  17.436  160.762 1.00 49.25  ? 301 ARG C CA  1 
ATOM   7745  C C   . ARG C 1 282 ? 39.115  17.975  160.718 1.00 49.57  ? 301 ARG C C   1 
ATOM   7746  O O   . ARG C 1 282 ? 38.681  18.547  161.733 1.00 51.43  ? 301 ARG C O   1 
ATOM   7747  C CB  . ARG C 1 282 ? 41.595  18.576  160.886 1.00 50.61  ? 301 ARG C CB  1 
ATOM   7748  N N   . LYS C 1 283 ? 38.409  17.728  159.615 1.00 48.03  ? 302 LYS C N   1 
ATOM   7749  C CA  . LYS C 1 283 ? 37.078  18.300  159.344 1.00 48.43  ? 302 LYS C CA  1 
ATOM   7750  C C   . LYS C 1 283 ? 35.953  17.621  160.135 1.00 49.23  ? 302 LYS C C   1 
ATOM   7751  O O   . LYS C 1 283 ? 36.020  16.422  160.398 1.00 49.21  ? 302 LYS C O   1 
ATOM   7752  C CB  . LYS C 1 283 ? 36.738  18.110  157.856 1.00 47.70  ? 302 LYS C CB  1 
ATOM   7753  C CG  . LYS C 1 283 ? 37.533  18.907  156.865 1.00 48.04  ? 302 LYS C CG  1 
ATOM   7754  C CD  . LYS C 1 283 ? 37.891  20.262  157.395 1.00 50.40  ? 302 LYS C CD  1 
ATOM   7755  C CE  . LYS C 1 283 ? 38.381  21.083  156.251 1.00 51.03  ? 302 LYS C CE  1 
ATOM   7756  N NZ  . LYS C 1 283 ? 38.420  22.493  156.622 1.00 53.14  ? 302 LYS C NZ  1 
ATOM   7757  N N   . PRO C 1 284 ? 34.859  18.342  160.439 1.00 48.47  ? 303 PRO C N   1 
ATOM   7758  C CA  . PRO C 1 284 ? 33.746  17.715  161.165 1.00 49.81  ? 303 PRO C CA  1 
ATOM   7759  C C   . PRO C 1 284 ? 33.265  16.480  160.429 1.00 49.17  ? 303 PRO C C   1 
ATOM   7760  O O   . PRO C 1 284 ? 33.306  16.418  159.201 1.00 48.10  ? 303 PRO C O   1 
ATOM   7761  C CB  . PRO C 1 284 ? 32.649  18.795  161.176 1.00 51.09  ? 303 PRO C CB  1 
ATOM   7762  C CG  . PRO C 1 284 ? 33.318  20.048  160.890 1.00 51.11  ? 303 PRO C CG  1 
ATOM   7763  C CD  . PRO C 1 284 ? 34.465  19.685  159.957 1.00 49.27  ? 303 PRO C CD  1 
ATOM   7764  N N   . LEU C 1 285 ? 32.771  15.509  161.190 1.00 49.74  ? 304 LEU C N   1 
ATOM   7765  C CA  . LEU C 1 285 ? 32.252  14.299  160.573 1.00 49.55  ? 304 LEU C CA  1 
ATOM   7766  C C   . LEU C 1 285 ? 31.118  14.629  159.612 1.00 49.89  ? 304 LEU C C   1 
ATOM   7767  O O   . LEU C 1 285 ? 31.025  14.044  158.520 1.00 49.03  ? 304 LEU C O   1 
ATOM   7768  C CB  . LEU C 1 285 ? 31.791  13.341  161.660 1.00 50.91  ? 304 LEU C CB  1 
ATOM   7769  C CG  . LEU C 1 285 ? 31.282  12.029  161.100 1.00 51.18  ? 304 LEU C CG  1 
ATOM   7770  C CD1 . LEU C 1 285 ? 32.332  11.428  160.184 1.00 49.51  ? 304 LEU C CD1 1 
ATOM   7771  C CD2 . LEU C 1 285 ? 30.932  11.084  162.219 1.00 52.38  ? 304 LEU C CD2 1 
ATOM   7772  N N   . THR C 1 286 ? 30.255  15.582  160.000 1.00 49.65  ? 305 THR C N   1 
ATOM   7773  C CA  . THR C 1 286 ? 29.125  15.965  159.153 1.00 50.50  ? 305 THR C CA  1 
ATOM   7774  C C   . THR C 1 286 ? 29.599  16.424  157.777 1.00 48.75  ? 305 THR C C   1 
ATOM   7775  O O   . THR C 1 286 ? 28.938  16.185  156.757 1.00 49.45  ? 305 THR C O   1 
ATOM   7776  C CB  . THR C 1 286 ? 28.323  17.091  159.819 1.00 52.82  ? 305 THR C CB  1 
ATOM   7777  O OG1 . THR C 1 286 ? 27.444  17.699  158.853 1.00 53.66  ? 305 THR C OG1 1 
ATOM   7778  C CG2 . THR C 1 286 ? 29.236  18.202  160.381 1.00 52.81  ? 305 THR C CG2 1 
ATOM   7779  N N   . GLN C 1 287 ? 30.727  17.131  157.744 1.00 48.73  ? 306 GLN C N   1 
ATOM   7780  C CA  . GLN C 1 287 ? 31.312  17.545  156.484 1.00 47.39  ? 306 GLN C CA  1 
ATOM   7781  C C   . GLN C 1 287 ? 31.883  16.348  155.747 1.00 45.82  ? 306 GLN C C   1 
ATOM   7782  O O   . GLN C 1 287 ? 31.663  16.194  154.544 1.00 44.95  ? 306 GLN C O   1 
ATOM   7783  C CB  . GLN C 1 287 ? 32.376  18.604  156.760 1.00 47.31  ? 306 GLN C CB  1 
ATOM   7784  C CG  . GLN C 1 287 ? 33.021  19.154  155.539 1.00 46.09  ? 306 GLN C CG  1 
ATOM   7785  C CD  . GLN C 1 287 ? 33.931  20.322  155.840 1.00 46.57  ? 306 GLN C CD  1 
ATOM   7786  O OE1 . GLN C 1 287 ? 33.623  21.214  156.658 1.00 47.80  ? 306 GLN C OE1 1 
ATOM   7787  N NE2 . GLN C 1 287 ? 35.068  20.339  155.170 1.00 45.75  ? 306 GLN C NE2 1 
ATOM   7788  N N   . LYS C 1 288 ? 32.589  15.470  156.460 1.00 46.94  ? 307 LYS C N   1 
ATOM   7789  C CA  . LYS C 1 288 ? 33.141  14.273  155.848 1.00 45.78  ? 307 LYS C CA  1 
ATOM   7790  C C   . LYS C 1 288 ? 32.088  13.460  155.130 1.00 46.67  ? 307 LYS C C   1 
ATOM   7791  O O   . LYS C 1 288 ? 32.357  12.882  154.077 1.00 45.74  ? 307 LYS C O   1 
ATOM   7792  C CB  . LYS C 1 288 ? 33.766  13.405  156.919 1.00 45.83  ? 307 LYS C CB  1 
ATOM   7793  C CG  . LYS C 1 288 ? 34.908  14.014  157.631 1.00 45.48  ? 307 LYS C CG  1 
ATOM   7794  C CD  . LYS C 1 288 ? 35.583  12.863  158.289 1.00 45.72  ? 307 LYS C CD  1 
ATOM   7795  C CE  . LYS C 1 288 ? 37.052  12.812  157.914 1.00 44.46  ? 307 LYS C CE  1 
ATOM   7796  N NZ  . LYS C 1 288 ? 37.876  13.496  159.008 1.00 45.23  ? 307 LYS C NZ  1 
ATOM   7797  N N   . ARG C 1 289 ? 30.890  13.385  155.710 1.00 44.53  ? 308 ARG C N   1 
ATOM   7798  C CA  . ARG C 1 289 ? 29.787  12.662  155.098 1.00 45.90  ? 308 ARG C CA  1 
ATOM   7799  C C   . ARG C 1 289 ? 29.143  13.434  153.961 1.00 46.08  ? 308 ARG C C   1 
ATOM   7800  O O   . ARG C 1 289 ? 28.783  12.835  152.943 1.00 46.18  ? 308 ARG C O   1 
ATOM   7801  C CB  . ARG C 1 289 ? 28.717  12.370  156.132 1.00 48.34  ? 308 ARG C CB  1 
ATOM   7802  C CG  . ARG C 1 289 ? 29.124  11.357  157.102 1.00 48.88  ? 308 ARG C CG  1 
ATOM   7803  C CD  . ARG C 1 289 ? 28.053  11.235  158.121 1.00 51.16  ? 308 ARG C CD  1 
ATOM   7804  N NE  . ARG C 1 289 ? 28.333  10.128  159.024 1.00 51.26  ? 308 ARG C NE  1 
ATOM   7805  C CZ  . ARG C 1 289 ? 27.963  10.114  160.297 1.00 52.63  ? 308 ARG C CZ  1 
ATOM   7806  N NH1 . ARG C 1 289 ? 27.265  11.115  160.819 1.00 54.10  ? 308 ARG C NH1 1 
ATOM   7807  N NH2 . ARG C 1 289 ? 28.300  9.077   161.064 1.00 52.55  ? 308 ARG C NH2 1 
ATOM   7808  N N   . ARG C 1 290 ? 28.923  14.749  154.152 1.00 45.79  ? 309 ARG C N   1 
ATOM   7809  C CA  . ARG C 1 290 ? 28.496  15.595  153.042 1.00 45.54  ? 309 ARG C CA  1 
ATOM   7810  C C   . ARG C 1 290 ? 29.390  15.311  151.848 1.00 43.22  ? 309 ARG C C   1 
ATOM   7811  O O   . ARG C 1 290 ? 28.924  14.935  150.763 1.00 43.05  ? 309 ARG C O   1 
ATOM   7812  C CB  . ARG C 1 290 ? 28.544  17.083  153.421 1.00 46.63  ? 309 ARG C CB  1 
ATOM   7813  N N   . VAL C 1 291 ? 30.699  15.405  152.082 1.00 43.92  ? 310 VAL C N   1 
ATOM   7814  C CA  . VAL C 1 291 ? 31.691  15.190  151.037 1.00 42.11  ? 310 VAL C CA  1 
ATOM   7815  C C   . VAL C 1 291 ? 31.609  13.765  150.493 1.00 41.59  ? 310 VAL C C   1 
ATOM   7816  O O   . VAL C 1 291 ? 31.730  13.557  149.280 1.00 40.53  ? 310 VAL C O   1 
ATOM   7817  C CB  . VAL C 1 291 ? 33.084  15.532  151.596 1.00 41.13  ? 310 VAL C CB  1 
ATOM   7818  C CG1 . VAL C 1 291 ? 34.190  15.196  150.631 1.00 39.79  ? 310 VAL C CG1 1 
ATOM   7819  C CG2 . VAL C 1 291 ? 33.131  17.021  151.963 1.00 41.78  ? 310 VAL C CG2 1 
ATOM   7820  N N   . ALA C 1 292 ? 31.395  12.761  151.361 1.00 41.30  ? 311 ALA C N   1 
ATOM   7821  C CA  . ALA C 1 292 ? 31.300  11.386  150.848 1.00 41.07  ? 311 ALA C CA  1 
ATOM   7822  C C   . ALA C 1 292 ? 30.044  11.210  149.992 1.00 41.80  ? 311 ALA C C   1 
ATOM   7823  O O   . ALA C 1 292 ? 30.118  10.641  148.908 1.00 40.25  ? 311 ALA C O   1 
ATOM   7824  C CB  . ALA C 1 292 ? 31.343  10.348  151.985 1.00 42.46  ? 311 ALA C CB  1 
ATOM   7825  N N   . LYS C 1 293 ? 28.898  11.752  150.435 1.00 43.11  ? 312 LYS C N   1 
ATOM   7826  C CA  . LYS C 1 293 ? 27.685  11.771  149.610 1.00 43.45  ? 312 LYS C CA  1 
ATOM   7827  C C   . LYS C 1 293 ? 27.925  12.405  148.234 1.00 41.75  ? 312 LYS C C   1 
ATOM   7828  O O   . LYS C 1 293 ? 27.463  11.898  147.212 1.00 40.94  ? 312 LYS C O   1 
ATOM   7829  C CB  . LYS C 1 293 ? 26.556  12.518  150.349 1.00 46.06  ? 312 LYS C CB  1 
ATOM   7830  N N   . ASP C 1 294 ? 28.696  13.482  148.182 1.00 43.54  ? 313 ASP C N   1 
ATOM   7831  C CA  . ASP C 1 294 ? 28.925  14.198  146.931 1.00 43.18  ? 313 ASP C CA  1 
ATOM   7832  C C   . ASP C 1 294 ? 29.981  13.561  146.039 1.00 41.28  ? 313 ASP C C   1 
ATOM   7833  O O   . ASP C 1 294 ? 29.944  13.752  144.821 1.00 41.20  ? 313 ASP C O   1 
ATOM   7834  C CB  . ASP C 1 294 ? 29.352  15.632  147.267 1.00 44.37  ? 313 ASP C CB  1 
ATOM   7835  C CG  . ASP C 1 294 ? 28.213  16.457  147.867 1.00 47.44  ? 313 ASP C CG  1 
ATOM   7836  O OD1 . ASP C 1 294 ? 27.035  16.146  147.576 1.00 48.86  ? 313 ASP C OD1 1 
ATOM   7837  O OD2 . ASP C 1 294 ? 28.482  17.406  148.641 1.00 48.38  ? 313 ASP C OD2 1 
ATOM   7838  N N   . SER C 1 295 ? 30.945  12.849  146.607 1.00 40.35  ? 314 SER C N   1 
ATOM   7839  C CA  . SER C 1 295 ? 32.079  12.325  145.859 1.00 38.57  ? 314 SER C CA  1 
ATOM   7840  C C   . SER C 1 295 ? 31.815  10.914  145.307 1.00 37.75  ? 314 SER C C   1 
ATOM   7841  O O   . SER C 1 295 ? 32.735  10.239  144.809 1.00 36.71  ? 314 SER C O   1 
ATOM   7842  C CB  . SER C 1 295 ? 33.299  12.297  146.773 1.00 38.38  ? 314 SER C CB  1 
ATOM   7843  O OG  . SER C 1 295 ? 33.660  13.586  147.181 1.00 39.11  ? 314 SER C OG  1 
ATOM   7844  N N   . LEU C 1 296 ? 30.582  10.448  145.424 1.00 40.61  ? 315 LEU C N   1 
ATOM   7845  C CA  . LEU C 1 296 ? 30.329  9.046   145.149 1.00 39.56  ? 315 LEU C CA  1 
ATOM   7846  C C   . LEU C 1 296 ? 30.142  8.800   143.658 1.00 38.77  ? 315 LEU C C   1 
ATOM   7847  O O   . LEU C 1 296 ? 30.663  7.816   143.120 1.00 37.42  ? 315 LEU C O   1 
ATOM   7848  C CB  . LEU C 1 296 ? 29.110  8.586   145.933 1.00 40.88  ? 315 LEU C CB  1 
ATOM   7849  C CG  . LEU C 1 296 ? 28.646  7.177   145.574 1.00 39.69  ? 315 LEU C CG  1 
ATOM   7850  C CD1 . LEU C 1 296 ? 29.760  6.166   145.789 1.00 38.45  ? 315 LEU C CD1 1 
ATOM   7851  C CD2 . LEU C 1 296 ? 27.418  6.831   146.402 1.00 41.49  ? 315 LEU C CD2 1 
ATOM   7852  N N   . LYS C 1 297 ? 29.436  9.698   142.970 1.00 40.87  ? 316 LYS C N   1 
ATOM   7853  C CA  . LYS C 1 297 ? 28.979  9.389   141.630 1.00 40.36  ? 316 LYS C CA  1 
ATOM   7854  C C   . LYS C 1 297 ? 30.145  9.057   140.715 1.00 39.34  ? 316 LYS C C   1 
ATOM   7855  O O   . LYS C 1 297 ? 30.054  8.130   139.899 1.00 38.80  ? 316 LYS C O   1 
ATOM   7856  C CB  . LYS C 1 297 ? 28.135  10.551  141.089 1.00 42.44  ? 316 LYS C CB  1 
ATOM   7857  C CG  . LYS C 1 297 ? 27.505  10.252  139.718 1.00 43.49  ? 316 LYS C CG  1 
ATOM   7858  C CD  . LYS C 1 297 ? 26.155  10.890  139.498 1.00 46.34  ? 316 LYS C CD  1 
ATOM   7859  C CE  . LYS C 1 297 ? 26.143  12.322  139.891 1.00 48.56  ? 316 LYS C CE  1 
ATOM   7860  N NZ  . LYS C 1 297 ? 27.160  13.120  139.157 1.00 48.90  ? 316 LYS C NZ  1 
ATOM   7861  N N   . PHE C 1 298 ? 31.274  9.757   140.841 1.00 39.61  ? 317 PHE C N   1 
ATOM   7862  C CA  . PHE C 1 298 ? 32.345  9.514   139.893 1.00 38.98  ? 317 PHE C CA  1 
ATOM   7863  C C   . PHE C 1 298 ? 32.954  8.103   140.031 1.00 37.80  ? 317 PHE C C   1 
ATOM   7864  O O   . PHE C 1 298 ? 32.947  7.341   139.064 1.00 37.66  ? 317 PHE C O   1 
ATOM   7865  C CB  . PHE C 1 298 ? 33.416  10.605  139.996 1.00 39.29  ? 317 PHE C CB  1 
ATOM   7866  C CG  . PHE C 1 298 ? 34.564  10.391  139.064 1.00 39.31  ? 317 PHE C CG  1 
ATOM   7867  C CD1 . PHE C 1 298 ? 34.383  10.499  137.696 1.00 39.69  ? 317 PHE C CD1 1 
ATOM   7868  C CD2 . PHE C 1 298 ? 35.798  10.000  139.535 1.00 39.23  ? 317 PHE C CD2 1 
ATOM   7869  C CE1 . PHE C 1 298 ? 35.415  10.254  136.822 1.00 40.14  ? 317 PHE C CE1 1 
ATOM   7870  C CE2 . PHE C 1 298 ? 36.836  9.755   138.662 1.00 39.62  ? 317 PHE C CE2 1 
ATOM   7871  C CZ  . PHE C 1 298 ? 36.636  9.889   137.301 1.00 39.99  ? 317 PHE C CZ  1 
ATOM   7872  N N   . PRO C 1 299 ? 33.529  7.733   141.175 1.00 38.40  ? 318 PRO C N   1 
ATOM   7873  C CA  . PRO C 1 299 ? 34.186  6.412   141.226 1.00 37.83  ? 318 PRO C CA  1 
ATOM   7874  C C   . PRO C 1 299 ? 33.207  5.268   141.035 1.00 37.29  ? 318 PRO C C   1 
ATOM   7875  O O   . PRO C 1 299 ? 33.588  4.229   140.487 1.00 36.63  ? 318 PRO C O   1 
ATOM   7876  C CB  . PRO C 1 299 ? 34.843  6.392   142.621 1.00 38.28  ? 318 PRO C CB  1 
ATOM   7877  C CG  . PRO C 1 299 ? 34.091  7.428   143.422 1.00 39.08  ? 318 PRO C CG  1 
ATOM   7878  C CD  . PRO C 1 299 ? 33.679  8.490   142.437 1.00 39.06  ? 318 PRO C CD  1 
ATOM   7879  N N   . LEU C 1 300 ? 31.948  5.437   141.442 1.00 36.96  ? 319 LEU C N   1 
ATOM   7880  C CA  . LEU C 1 300 ? 30.957  4.396   141.201 1.00 36.73  ? 319 LEU C CA  1 
ATOM   7881  C C   . LEU C 1 300 ? 30.722  4.217   139.707 1.00 36.74  ? 319 LEU C C   1 
ATOM   7882  O O   . LEU C 1 300 ? 30.843  3.116   139.179 1.00 36.87  ? 319 LEU C O   1 
ATOM   7883  C CB  . LEU C 1 300 ? 29.656  4.736   141.929 1.00 37.54  ? 319 LEU C CB  1 
ATOM   7884  C CG  . LEU C 1 300 ? 28.513  3.740   141.696 1.00 37.67  ? 319 LEU C CG  1 
ATOM   7885  C CD1 . LEU C 1 300 ? 28.923  2.332   142.102 1.00 36.92  ? 319 LEU C CD1 1 
ATOM   7886  C CD2 . LEU C 1 300 ? 27.295  4.198   142.500 1.00 39.03  ? 319 LEU C CD2 1 
ATOM   7887  N N   . ALA C 1 301 ? 30.423  5.310   139.004 1.00 38.30  ? 320 ALA C N   1 
ATOM   7888  C CA  . ALA C 1 301 ? 30.290  5.259   137.554 1.00 38.96  ? 320 ALA C CA  1 
ATOM   7889  C C   . ALA C 1 301 ? 31.505  4.602   136.922 1.00 38.55  ? 320 ALA C C   1 
ATOM   7890  O O   . ALA C 1 301 ? 31.370  3.798   135.993 1.00 39.17  ? 320 ALA C O   1 
ATOM   7891  C CB  . ALA C 1 301 ? 30.086  6.676   136.984 1.00 40.21  ? 320 ALA C CB  1 
ATOM   7892  N N   . CYS C 1 302 ? 32.704  4.965   137.390 1.00 40.03  ? 321 CYS C N   1 
ATOM   7893  C CA  . CYS C 1 302 ? 33.900  4.348   136.851 1.00 40.16  ? 321 CYS C CA  1 
ATOM   7894  C C   . CYS C 1 302 ? 33.868  2.853   137.111 1.00 39.63  ? 321 CYS C C   1 
ATOM   7895  O O   . CYS C 1 302 ? 34.214  2.045   136.233 1.00 40.32  ? 321 CYS C O   1 
ATOM   7896  C CB  . CYS C 1 302 ? 35.148  4.940   137.480 1.00 40.43  ? 321 CYS C CB  1 
ATOM   7897  S SG  . CYS C 1 302 ? 35.612  6.537   136.897 1.00 41.38  ? 321 CYS C SG  1 
ATOM   7898  N N   . PHE C 1 303 ? 33.466  2.466   138.325 1.00 37.92  ? 322 PHE C N   1 
ATOM   7899  C CA  . PHE C 1 303 ? 33.333  1.049   138.627 1.00 37.53  ? 322 PHE C CA  1 
ATOM   7900  C C   . PHE C 1 303 ? 32.349  0.397   137.662 1.00 38.18  ? 322 PHE C C   1 
ATOM   7901  O O   . PHE C 1 303 ? 32.702  -0.549  136.950 1.00 38.70  ? 322 PHE C O   1 
ATOM   7902  C CB  . PHE C 1 303 ? 32.909  0.867   140.083 1.00 36.89  ? 322 PHE C CB  1 
ATOM   7903  C CG  . PHE C 1 303 ? 32.527  -0.518  140.410 1.00 36.33  ? 322 PHE C CG  1 
ATOM   7904  C CD1 . PHE C 1 303 ? 33.494  -1.514  140.534 1.00 36.45  ? 322 PHE C CD1 1 
ATOM   7905  C CD2 . PHE C 1 303 ? 31.198  -0.863  140.565 1.00 36.93  ? 322 PHE C CD2 1 
ATOM   7906  C CE1 . PHE C 1 303 ? 33.140  -2.826  140.791 1.00 36.71  ? 322 PHE C CE1 1 
ATOM   7907  C CE2 . PHE C 1 303 ? 30.854  -2.203  140.867 1.00 36.94  ? 322 PHE C CE2 1 
ATOM   7908  C CZ  . PHE C 1 303 ? 31.834  -3.160  140.972 1.00 36.96  ? 322 PHE C CZ  1 
ATOM   7909  N N   . LEU C 1 304 ? 31.127  0.945   137.568 1.00 35.93  ? 323 LEU C N   1 
ATOM   7910  C CA  . LEU C 1 304 ? 30.099  0.327   136.734 1.00 36.88  ? 323 LEU C CA  1 
ATOM   7911  C C   . LEU C 1 304 ? 30.426  0.431   135.252 1.00 38.06  ? 323 LEU C C   1 
ATOM   7912  O O   . LEU C 1 304 ? 29.928  -0.366  134.464 1.00 39.25  ? 323 LEU C O   1 
ATOM   7913  C CB  . LEU C 1 304 ? 28.739  0.949   137.026 1.00 37.74  ? 323 LEU C CB  1 
ATOM   7914  C CG  . LEU C 1 304 ? 28.213  0.733   138.430 1.00 37.50  ? 323 LEU C CG  1 
ATOM   7915  C CD1 . LEU C 1 304 ? 26.902  1.408   138.696 1.00 38.71  ? 323 LEU C CD1 1 
ATOM   7916  C CD2 . LEU C 1 304 ? 28.042  -0.743  138.733 1.00 37.83  ? 323 LEU C CD2 1 
ATOM   7917  N N   . ALA C 1 305 ? 31.263  1.384   134.850 1.00 37.92  ? 324 ALA C N   1 
ATOM   7918  C CA  . ALA C 1 305 ? 31.678  1.433   133.454 1.00 39.22  ? 324 ALA C CA  1 
ATOM   7919  C C   . ALA C 1 305 ? 32.426  0.165   133.072 1.00 39.50  ? 324 ALA C C   1 
ATOM   7920  O O   . ALA C 1 305 ? 32.315  -0.316  131.943 1.00 40.98  ? 324 ALA C O   1 
ATOM   7921  C CB  . ALA C 1 305 ? 32.566  2.651   133.190 1.00 39.73  ? 324 ALA C CB  1 
ATOM   7922  N N   . GLY C 1 306 ? 33.204  -0.375  133.989 1.00 38.97  ? 325 GLY C N   1 
ATOM   7923  C CA  . GLY C 1 306 ? 34.155  -1.402  133.642 1.00 39.75  ? 325 GLY C CA  1 
ATOM   7924  C C   . GLY C 1 306 ? 33.888  -2.717  134.335 1.00 39.65  ? 325 GLY C C   1 
ATOM   7925  O O   . GLY C 1 306 ? 34.655  -3.676  134.155 1.00 40.61  ? 325 GLY C O   1 
ATOM   7926  N N   . ALA C 1 307 ? 32.808  -2.781  135.112 1.00 39.90  ? 326 ALA C N   1 
ATOM   7927  C CA  . ALA C 1 307 ? 32.557  -3.927  135.974 1.00 39.91  ? 326 ALA C CA  1 
ATOM   7928  C C   . ALA C 1 307 ? 32.040  -5.111  135.170 1.00 41.32  ? 326 ALA C C   1 
ATOM   7929  O O   . ALA C 1 307 ? 31.246  -4.937  134.238 1.00 42.16  ? 326 ALA C O   1 
ATOM   7930  C CB  . ALA C 1 307 ? 31.552  -3.576  137.067 1.00 39.14  ? 326 ALA C CB  1 
ATOM   7931  N N   . GLN C 1 308 ? 32.515  -6.310  135.543 1.00 39.81  ? 327 GLN C N   1 
ATOM   7932  C CA  . GLN C 1 308 ? 32.092  -7.625  135.064 1.00 40.84  ? 327 GLN C CA  1 
ATOM   7933  C C   . GLN C 1 308 ? 31.730  -8.513  136.263 1.00 40.60  ? 327 GLN C C   1 
ATOM   7934  O O   . GLN C 1 308 ? 31.856  -8.117  137.424 1.00 39.74  ? 327 GLN C O   1 
ATOM   7935  C CB  . GLN C 1 308 ? 33.211  -8.301  134.252 1.00 42.26  ? 327 GLN C CB  1 
ATOM   7936  C CG  . GLN C 1 308 ? 34.030  -7.394  133.360 1.00 42.81  ? 327 GLN C CG  1 
ATOM   7937  C CD  . GLN C 1 308 ? 33.249  -6.887  132.138 1.00 43.41  ? 327 GLN C CD  1 
ATOM   7938  O OE1 . GLN C 1 308 ? 32.486  -7.628  131.488 1.00 44.97  ? 327 GLN C OE1 1 
ATOM   7939  N NE2 . GLN C 1 308 ? 33.462  -5.641  131.813 1.00 43.26  ? 327 GLN C NE2 1 
ATOM   7940  N N   . GLU C 1 309 ? 31.314  -9.751  136.002 1.00 40.23  ? 328 GLU C N   1 
ATOM   7941  C CA  . GLU C 1 309 ? 31.070  -10.691 137.096 1.00 40.26  ? 328 GLU C CA  1 
ATOM   7942  C C   . GLU C 1 309 ? 32.299  -10.736 138.000 1.00 38.99  ? 328 GLU C C   1 
ATOM   7943  O O   . GLU C 1 309 ? 33.432  -10.637 137.532 1.00 39.42  ? 328 GLU C O   1 
ATOM   7944  C CB  . GLU C 1 309 ? 30.726  -12.099 136.563 1.00 42.66  ? 328 GLU C CB  1 
ATOM   7945  N N   . ASN C 1 310 ? 32.056  -10.821 139.309 1.00 39.02  ? 329 ASN C N   1 
ATOM   7946  C CA  . ASN C 1 310 ? 33.105  -10.951 140.324 1.00 37.87  ? 329 ASN C CA  1 
ATOM   7947  C C   . ASN C 1 310 ? 33.911  -9.669  140.539 1.00 36.89  ? 329 ASN C C   1 
ATOM   7948  O O   . ASN C 1 310 ? 35.068  -9.735  140.971 1.00 36.58  ? 329 ASN C O   1 
ATOM   7949  C CB  . ASN C 1 310 ? 34.087  -12.079 140.011 1.00 38.64  ? 329 ASN C CB  1 
ATOM   7950  C CG  . ASN C 1 310 ? 33.401  -13.357 139.614 1.00 39.75  ? 329 ASN C CG  1 
ATOM   7951  O OD1 . ASN C 1 310 ? 32.524  -13.869 140.325 1.00 39.88  ? 329 ASN C OD1 1 
ATOM   7952  N ND2 . ASN C 1 310 ? 33.769  -13.858 138.450 1.00 41.22  ? 329 ASN C ND2 1 
ATOM   7953  N N   . CYS C 1 311 ? 33.345  -8.498  140.237 1.00 37.58  ? 330 CYS C N   1 
ATOM   7954  C CA  . CYS C 1 311 ? 33.987  -7.216  140.533 1.00 36.47  ? 330 CYS C CA  1 
ATOM   7955  C C   . CYS C 1 311 ? 33.251  -6.577  141.705 1.00 35.50  ? 330 CYS C C   1 
ATOM   7956  O O   . CYS C 1 311 ? 32.021  -6.685  141.816 1.00 36.08  ? 330 CYS C O   1 
ATOM   7957  C CB  . CYS C 1 311 ? 33.989  -6.297  139.307 1.00 37.29  ? 330 CYS C CB  1 
ATOM   7958  S SG  . CYS C 1 311 ? 35.166  -6.806  137.975 1.00 39.14  ? 330 CYS C SG  1 
ATOM   7959  N N   . TYR C 1 312 ? 34.006  -5.954  142.606 1.00 36.55  ? 331 TYR C N   1 
ATOM   7960  C CA  . TYR C 1 312 ? 33.454  -5.441  143.846 1.00 35.84  ? 331 TYR C CA  1 
ATOM   7961  C C   . TYR C 1 312 ? 33.871  -3.996  144.047 1.00 35.44  ? 331 TYR C C   1 
ATOM   7962  O O   . TYR C 1 312 ? 34.952  -3.574  143.641 1.00 35.80  ? 331 TYR C O   1 
ATOM   7963  C CB  . TYR C 1 312 ? 33.903  -6.296  145.052 1.00 35.88  ? 331 TYR C CB  1 
ATOM   7964  C CG  . TYR C 1 312 ? 33.238  -7.669  145.009 1.00 36.47  ? 331 TYR C CG  1 
ATOM   7965  C CD1 . TYR C 1 312 ? 33.827  -8.733  144.329 1.00 37.00  ? 331 TYR C CD1 1 
ATOM   7966  C CD2 . TYR C 1 312 ? 31.994  -7.868  145.597 1.00 37.04  ? 331 TYR C CD2 1 
ATOM   7967  C CE1 . TYR C 1 312 ? 33.183  -9.997  144.252 1.00 37.62  ? 331 TYR C CE1 1 
ATOM   7968  C CE2 . TYR C 1 312 ? 31.357  -9.084  145.523 1.00 37.96  ? 331 TYR C CE2 1 
ATOM   7969  C CZ  . TYR C 1 312 ? 31.949  -10.130 144.862 1.00 38.37  ? 331 TYR C CZ  1 
ATOM   7970  O OH  . TYR C 1 312 ? 31.260  -11.269 144.839 1.00 39.64  ? 331 TYR C OH  1 
ATOM   7971  N N   . PHE C 1 313 ? 33.002  -3.265  144.722 1.00 33.05  ? 332 PHE C N   1 
ATOM   7972  C CA  . PHE C 1 313 ? 33.193  -1.866  145.007 1.00 33.14  ? 332 PHE C CA  1 
ATOM   7973  C C   . PHE C 1 313 ? 33.258  -1.677  146.512 1.00 33.33  ? 332 PHE C C   1 
ATOM   7974  O O   . PHE C 1 313 ? 32.422  -2.206  147.255 1.00 33.49  ? 332 PHE C O   1 
ATOM   7975  C CB  . PHE C 1 313 ? 32.067  -1.019  144.386 1.00 33.74  ? 332 PHE C CB  1 
ATOM   7976  C CG  . PHE C 1 313 ? 32.330  0.475   144.389 1.00 33.98  ? 332 PHE C CG  1 
ATOM   7977  C CD1 . PHE C 1 313 ? 33.440  1.001   143.770 1.00 34.17  ? 332 PHE C CD1 1 
ATOM   7978  C CD2 . PHE C 1 313 ? 31.435  1.341   144.987 1.00 34.73  ? 332 PHE C CD2 1 
ATOM   7979  C CE1 . PHE C 1 313 ? 33.669  2.308   143.765 1.00 35.08  ? 332 PHE C CE1 1 
ATOM   7980  C CE2 . PHE C 1 313 ? 31.653  2.681   144.967 1.00 35.61  ? 332 PHE C CE2 1 
ATOM   7981  C CZ  . PHE C 1 313 ? 32.768  3.168   144.348 1.00 35.81  ? 332 PHE C CZ  1 
ATOM   7982  N N   . ILE C 1 314 ? 34.251  -0.886  146.928 1.00 35.06  ? 333 ILE C N   1 
ATOM   7983  C CA  . ILE C 1 314 ? 34.475  -0.473  148.309 1.00 35.72  ? 333 ILE C CA  1 
ATOM   7984  C C   . ILE C 1 314 ? 34.541  1.041   148.315 1.00 36.65  ? 333 ILE C C   1 
ATOM   7985  O O   . ILE C 1 314 ? 35.268  1.629   147.503 1.00 37.45  ? 333 ILE C O   1 
ATOM   7986  C CB  . ILE C 1 314 ? 35.780  -1.039  148.890 1.00 35.73  ? 333 ILE C CB  1 
ATOM   7987  C CG1 . ILE C 1 314 ? 35.811  -2.550  148.717 1.00 35.45  ? 333 ILE C CG1 1 
ATOM   7988  C CG2 . ILE C 1 314 ? 35.947  -0.572  150.310 1.00 36.95  ? 333 ILE C CG2 1 
ATOM   7989  C CD1 . ILE C 1 314 ? 37.018  -3.161  149.389 1.00 36.05  ? 333 ILE C CD1 1 
ATOM   7990  N N   . TYR C 1 315 ? 33.799  1.677   149.219 1.00 33.90  ? 334 TYR C N   1 
ATOM   7991  C CA  . TYR C 1 315 ? 33.702  3.126   149.194 1.00 35.39  ? 334 TYR C CA  1 
ATOM   7992  C C   . TYR C 1 315 ? 33.742  3.686   150.603 1.00 36.91  ? 334 TYR C C   1 
ATOM   7993  O O   . TYR C 1 315 ? 32.821  3.463   151.398 1.00 38.00  ? 334 TYR C O   1 
ATOM   7994  C CB  . TYR C 1 315 ? 32.432  3.583   148.488 1.00 35.70  ? 334 TYR C CB  1 
ATOM   7995  C CG  . TYR C 1 315 ? 32.370  5.093   148.347 1.00 37.24  ? 334 TYR C CG  1 
ATOM   7996  C CD1 . TYR C 1 315 ? 33.230  5.749   147.502 1.00 37.00  ? 334 TYR C CD1 1 
ATOM   7997  C CD2 . TYR C 1 315 ? 31.474  5.849   149.078 1.00 39.13  ? 334 TYR C CD2 1 
ATOM   7998  C CE1 . TYR C 1 315 ? 33.193  7.119   147.361 1.00 38.09  ? 334 TYR C CE1 1 
ATOM   7999  C CE2 . TYR C 1 315 ? 31.415  7.241   148.930 1.00 40.58  ? 334 TYR C CE2 1 
ATOM   8000  C CZ  . TYR C 1 315 ? 32.275  7.859   148.053 1.00 39.76  ? 334 TYR C CZ  1 
ATOM   8001  O OH  . TYR C 1 315 ? 32.267  9.227   147.870 1.00 40.55  ? 334 TYR C OH  1 
ATOM   8002  N N   . ASN C 1 316 ? 34.791  4.459   150.877 1.00 36.79  ? 335 ASN C N   1 
ATOM   8003  C CA  . ASN C 1 316 ? 35.056  5.055   152.183 1.00 37.85  ? 335 ASN C CA  1 
ATOM   8004  C C   . ASN C 1 316 ? 36.329  5.901   152.080 1.00 38.02  ? 335 ASN C C   1 
ATOM   8005  O O   . ASN C 1 316 ? 36.935  5.997   151.007 1.00 37.38  ? 335 ASN C O   1 
ATOM   8006  C CB  . ASN C 1 316 ? 35.194  3.971   153.230 1.00 37.34  ? 335 ASN C CB  1 
ATOM   8007  C CG  . ASN C 1 316 ? 36.280  2.991   152.891 1.00 35.93  ? 335 ASN C CG  1 
ATOM   8008  O OD1 . ASN C 1 316 ? 37.418  3.377   152.645 1.00 36.00  ? 335 ASN C OD1 1 
ATOM   8009  N ND2 . ASN C 1 316 ? 35.926  1.678   152.863 1.00 34.89  ? 335 ASN C ND2 1 
ATOM   8010  N N   . TRP C 1 317 ? 36.774  6.496   153.178 1.00 34.58  ? 336 TRP C N   1 
ATOM   8011  C CA  . TRP C 1 317 ? 37.985  7.298   153.126 1.00 35.09  ? 336 TRP C CA  1 
ATOM   8012  C C   . TRP C 1 317 ? 39.143  6.697   153.924 1.00 36.38  ? 336 TRP C C   1 
ATOM   8013  O O   . TRP C 1 317 ? 40.139  7.401   154.182 1.00 37.32  ? 336 TRP C O   1 
ATOM   8014  C CB  . TRP C 1 317 ? 37.667  8.742   153.573 1.00 35.92  ? 336 TRP C CB  1 
ATOM   8015  C CG  . TRP C 1 317 ? 37.077  8.940   154.942 1.00 37.53  ? 336 TRP C CG  1 
ATOM   8016  C CD1 . TRP C 1 317 ? 37.762  9.011   156.125 1.00 40.01  ? 336 TRP C CD1 1 
ATOM   8017  C CD2 . TRP C 1 317 ? 35.699  9.107   155.272 1.00 37.88  ? 336 TRP C CD2 1 
ATOM   8018  N NE1 . TRP C 1 317 ? 36.894  9.214   157.155 1.00 41.82  ? 336 TRP C NE1 1 
ATOM   8019  C CE2 . TRP C 1 317 ? 35.621  9.276   156.664 1.00 40.57  ? 336 TRP C CE2 1 
ATOM   8020  C CE3 . TRP C 1 317 ? 34.527  9.119   154.533 1.00 36.86  ? 336 TRP C CE3 1 
ATOM   8021  C CZ2 . TRP C 1 317 ? 34.417  9.465   157.325 1.00 42.42  ? 336 TRP C CZ2 1 
ATOM   8022  C CZ3 . TRP C 1 317 ? 33.334  9.313   155.197 1.00 38.03  ? 336 TRP C CZ3 1 
ATOM   8023  C CH2 . TRP C 1 317 ? 33.288  9.485   156.569 1.00 40.85  ? 336 TRP C CH2 1 
ATOM   8024  N N   . GLY C 1 318 ? 39.059  5.420   154.283 1.00 36.78  ? 337 GLY C N   1 
ATOM   8025  C CA  . GLY C 1 318 ? 40.149  4.741   154.971 1.00 37.71  ? 337 GLY C CA  1 
ATOM   8026  C C   . GLY C 1 318 ? 39.820  3.312   155.390 1.00 38.38  ? 337 GLY C C   1 
ATOM   8027  O O   . GLY C 1 318 ? 38.706  2.806   155.204 1.00 37.89  ? 337 GLY C O   1 
ATOM   8028  N N   . TYR C 1 319 ? 40.823  2.699   156.035 1.00 39.08  ? 338 TYR C N   1 
ATOM   8029  C CA  . TYR C 1 319 ? 40.800  1.312   156.479 1.00 39.05  ? 338 TYR C CA  1 
ATOM   8030  C C   . TYR C 1 319 ? 40.522  1.095   157.965 1.00 40.40  ? 338 TYR C C   1 
ATOM   8031  O O   . TYR C 1 319 ? 40.465  -0.061  158.378 1.00 40.35  ? 338 TYR C O   1 
ATOM   8032  C CB  . TYR C 1 319 ? 42.138  0.653   156.151 1.00 38.87  ? 338 TYR C CB  1 
ATOM   8033  C CG  . TYR C 1 319 ? 42.470  0.777   154.713 1.00 38.14  ? 338 TYR C CG  1 
ATOM   8034  C CD1 . TYR C 1 319 ? 43.410  1.705   154.289 1.00 37.49  ? 338 TYR C CD1 1 
ATOM   8035  C CD2 . TYR C 1 319 ? 41.838  -0.027  153.755 1.00 38.69  ? 338 TYR C CD2 1 
ATOM   8036  C CE1 . TYR C 1 319 ? 43.737  1.836   152.942 1.00 37.12  ? 338 TYR C CE1 1 
ATOM   8037  C CE2 . TYR C 1 319 ? 42.127  0.125   152.393 1.00 38.04  ? 338 TYR C CE2 1 
ATOM   8038  C CZ  . TYR C 1 319 ? 43.088  1.037   151.993 1.00 37.34  ? 338 TYR C CZ  1 
ATOM   8039  O OH  . TYR C 1 319 ? 43.382  1.159   150.665 1.00 37.16  ? 338 TYR C OH  1 
ATOM   8040  N N   . ARG C 1 320 ? 40.333  2.134   158.776 1.00 38.02  ? 339 ARG C N   1 
ATOM   8041  C CA  . ARG C 1 320 ? 39.754  1.941   160.103 1.00 39.81  ? 339 ARG C CA  1 
ATOM   8042  C C   . ARG C 1 320 ? 38.236  2.031   159.954 1.00 39.82  ? 339 ARG C C   1 
ATOM   8043  O O   . ARG C 1 320 ? 37.706  2.726   159.073 1.00 39.43  ? 339 ARG C O   1 
ATOM   8044  C CB  . ARG C 1 320 ? 40.280  2.948   161.146 1.00 42.17  ? 339 ARG C CB  1 
ATOM   8045  N N   . MET C 1 321 ? 37.532  1.288   160.803 1.00 43.54  ? 340 MET C N   1 
ATOM   8046  C CA  . MET C 1 321 ? 36.080  1.172   160.653 1.00 44.24  ? 340 MET C CA  1 
ATOM   8047  C C   . MET C 1 321 ? 35.412  2.535   160.575 1.00 45.07  ? 340 MET C C   1 
ATOM   8048  O O   . MET C 1 321 ? 34.554  2.771   159.717 1.00 44.77  ? 340 MET C O   1 
ATOM   8049  C CB  . MET C 1 321 ? 35.511  0.374   161.825 1.00 46.01  ? 340 MET C CB  1 
ATOM   8050  C CG  . MET C 1 321 ? 34.235  -0.434  161.553 1.00 46.19  ? 340 MET C CG  1 
ATOM   8051  S SD  . MET C 1 321 ? 32.813  0.265   162.415 1.00 48.62  ? 340 MET C SD  1 
ATOM   8052  C CE  . MET C 1 321 ? 32.825  -0.377  164.056 1.00 52.44  ? 340 MET C CE  1 
ATOM   8053  N N   . GLU C 1 322 ? 35.829  3.470   161.441 1.00 43.20  ? 341 GLU C N   1 
ATOM   8054  C CA  . GLU C 1 322 ? 35.173  4.776   161.520 1.00 45.15  ? 341 GLU C CA  1 
ATOM   8055  C C   . GLU C 1 322 ? 35.411  5.648   160.287 1.00 43.31  ? 341 GLU C C   1 
ATOM   8056  O O   . GLU C 1 322 ? 34.616  6.565   160.039 1.00 43.96  ? 341 GLU C O   1 
ATOM   8057  C CB  . GLU C 1 322 ? 35.617  5.495   162.793 1.00 47.92  ? 341 GLU C CB  1 
ATOM   8058  C CG  . GLU C 1 322 ? 37.143  5.658   162.963 1.00 48.17  ? 341 GLU C CG  1 
ATOM   8059  C CD  . GLU C 1 322 ? 37.858  4.458   163.657 1.00 48.50  ? 341 GLU C CD  1 
ATOM   8060  O OE1 . GLU C 1 322 ? 37.227  3.360   163.804 1.00 48.34  ? 341 GLU C OE1 1 
ATOM   8061  O OE2 . GLU C 1 322 ? 39.041  4.608   164.066 1.00 49.65  ? 341 GLU C OE2 1 
ATOM   8062  N N   . ASN C 1 323 ? 36.413  5.352   159.469 1.00 43.08  ? 342 ASN C N   1 
ATOM   8063  C CA  . ASN C 1 323 ? 36.689  6.144   158.273 1.00 41.51  ? 342 ASN C CA  1 
ATOM   8064  C C   . ASN C 1 323 ? 35.639  5.991   157.157 1.00 39.99  ? 342 ASN C C   1 
ATOM   8065  O O   . ASN C 1 323 ? 35.988  5.843   155.977 1.00 37.84  ? 342 ASN C O   1 
ATOM   8066  C CB  . ASN C 1 323 ? 38.088  5.749   157.750 1.00 40.24  ? 342 ASN C CB  1 
ATOM   8067  C CG  . ASN C 1 323 ? 39.208  5.940   158.792 1.00 40.98  ? 342 ASN C CG  1 
ATOM   8068  O OD1 . ASN C 1 323 ? 39.085  6.720   159.780 1.00 40.62  ? 342 ASN C OD1 1 
ATOM   8069  N ND2 . ASN C 1 323 ? 40.316  5.222   158.580 1.00 43.20  ? 342 ASN C ND2 1 
ATOM   8070  N N   . GLY C 1 324 ? 34.354  6.063   157.507 1.00 42.38  ? 343 GLY C N   1 
ATOM   8071  C CA  . GLY C 1 324 ? 33.293  5.920   156.527 1.00 40.40  ? 343 GLY C CA  1 
ATOM   8072  C C   . GLY C 1 324 ? 33.000  4.517   156.022 1.00 38.56  ? 343 GLY C C   1 
ATOM   8073  O O   . GLY C 1 324 ? 32.352  4.348   154.983 1.00 36.38  ? 343 GLY C O   1 
ATOM   8074  N N   . CYS C 1 325 ? 33.470  3.487   156.700 1.00 42.14  ? 344 CYS C N   1 
ATOM   8075  C CA  . CYS C 1 325 ? 33.374  2.141   156.121 1.00 40.10  ? 344 CYS C CA  1 
ATOM   8076  C C   . CYS C 1 325 ? 31.957  1.593   156.174 1.00 40.19  ? 344 CYS C C   1 
ATOM   8077  O O   . CYS C 1 325 ? 31.588  0.758   155.337 1.00 38.86  ? 344 CYS C O   1 
ATOM   8078  C CB  . CYS C 1 325 ? 34.349  1.203   156.846 1.00 41.38  ? 344 CYS C CB  1 
ATOM   8079  S SG  . CYS C 1 325 ? 36.096  1.719   156.625 1.00 42.09  ? 344 CYS C SG  1 
ATOM   8080  N N   . LEU C 1 326 ? 31.167  2.089   157.114 1.00 39.04  ? 345 LEU C N   1 
ATOM   8081  C CA  . LEU C 1 326 ? 29.815  1.658   157.362 1.00 39.98  ? 345 LEU C CA  1 
ATOM   8082  C C   . LEU C 1 326 ? 28.824  2.743   157.000 1.00 40.77  ? 345 LEU C C   1 
ATOM   8083  O O   . LEU C 1 326 ? 27.663  2.672   157.422 1.00 42.90  ? 345 LEU C O   1 
ATOM   8084  C CB  . LEU C 1 326 ? 29.641  1.276   158.834 1.00 43.31  ? 345 LEU C CB  1 
ATOM   8085  C CG  . LEU C 1 326 ? 30.575  0.260   159.521 1.00 43.71  ? 345 LEU C CG  1 
ATOM   8086  C CD1 . LEU C 1 326 ? 30.023  -0.043  160.913 1.00 47.25  ? 345 LEU C CD1 1 
ATOM   8087  C CD2 . LEU C 1 326 ? 30.727  -1.029  158.687 1.00 40.97  ? 345 LEU C CD2 1 
ATOM   8088  N N   . GLU C 1 327 ? 29.257  3.777   156.285 1.00 44.16  ? 346 GLU C N   1 
ATOM   8089  C CA  . GLU C 1 327 ? 28.270  4.645   155.682 1.00 44.23  ? 346 GLU C CA  1 
ATOM   8090  C C   . GLU C 1 327 ? 27.521  3.845   154.638 1.00 43.03  ? 346 GLU C C   1 
ATOM   8091  O O   . GLU C 1 327 ? 28.010  2.839   154.139 1.00 42.37  ? 346 GLU C O   1 
ATOM   8092  C CB  . GLU C 1 327 ? 28.908  5.881   155.049 1.00 43.25  ? 346 GLU C CB  1 
ATOM   8093  C CG  . GLU C 1 327 ? 29.669  6.727   156.060 1.00 45.14  ? 346 GLU C CG  1 
ATOM   8094  C CD  . GLU C 1 327 ? 28.767  7.260   157.156 1.00 49.04  ? 346 GLU C CD  1 
ATOM   8095  O OE1 . GLU C 1 327 ? 27.631  7.668   156.833 1.00 49.76  ? 346 GLU C OE1 1 
ATOM   8096  O OE2 . GLU C 1 327 ? 29.194  7.247   158.346 1.00 52.71  ? 346 GLU C OE2 1 
ATOM   8097  N N   . TRP C 1 328 ? 26.329  4.304   154.298 1.00 45.46  ? 347 TRP C N   1 
ATOM   8098  C CA  . TRP C 1 328 ? 25.536  3.662   153.268 1.00 44.48  ? 347 TRP C CA  1 
ATOM   8099  C C   . TRP C 1 328 ? 24.886  4.751   152.420 1.00 44.84  ? 347 TRP C C   1 
ATOM   8100  O O   . TRP C 1 328 ? 24.680  5.891   152.864 1.00 46.47  ? 347 TRP C O   1 
ATOM   8101  C CB  . TRP C 1 328 ? 24.493  2.739   153.875 1.00 46.54  ? 347 TRP C CB  1 
ATOM   8102  C CG  . TRP C 1 328 ? 23.999  1.711   152.910 1.00 45.46  ? 347 TRP C CG  1 
ATOM   8103  C CD1 . TRP C 1 328 ? 22.717  1.558   152.460 1.00 46.77  ? 347 TRP C CD1 1 
ATOM   8104  C CD2 . TRP C 1 328 ? 24.772  0.685   152.279 1.00 43.16  ? 347 TRP C CD2 1 
ATOM   8105  N NE1 . TRP C 1 328 ? 22.647  0.499   151.590 1.00 45.91  ? 347 TRP C NE1 1 
ATOM   8106  C CE2 . TRP C 1 328 ? 23.900  -0.054  151.470 1.00 43.48  ? 347 TRP C CE2 1 
ATOM   8107  C CE3 . TRP C 1 328 ? 26.119  0.312   152.335 1.00 41.51  ? 347 TRP C CE3 1 
ATOM   8108  C CZ2 . TRP C 1 328 ? 24.334  -1.135  150.708 1.00 42.00  ? 347 TRP C CZ2 1 
ATOM   8109  C CZ3 . TRP C 1 328 ? 26.548  -0.767  151.576 1.00 40.09  ? 347 TRP C CZ3 1 
ATOM   8110  C CH2 . TRP C 1 328 ? 25.657  -1.467  150.763 1.00 40.44  ? 347 TRP C CH2 1 
ATOM   8111  N N   . TYR C 1 329 ? 24.551  4.368   151.182 1.00 44.69  ? 348 TYR C N   1 
ATOM   8112  C CA  . TYR C 1 329 ? 24.071  5.264   150.153 1.00 44.72  ? 348 TYR C CA  1 
ATOM   8113  C C   . TYR C 1 329 ? 22.944  4.596   149.380 1.00 45.56  ? 348 TYR C C   1 
ATOM   8114  O O   . TYR C 1 329 ? 22.990  3.381   149.132 1.00 45.07  ? 348 TYR C O   1 
ATOM   8115  C CB  . TYR C 1 329 ? 25.227  5.636   149.211 1.00 42.41  ? 348 TYR C CB  1 
ATOM   8116  C CG  . TYR C 1 329 ? 26.437  6.168   149.935 1.00 41.81  ? 348 TYR C CG  1 
ATOM   8117  C CD1 . TYR C 1 329 ? 27.400  5.305   150.451 1.00 40.93  ? 348 TYR C CD1 1 
ATOM   8118  C CD2 . TYR C 1 329 ? 26.607  7.542   150.136 1.00 42.54  ? 348 TYR C CD2 1 
ATOM   8119  C CE1 . TYR C 1 329 ? 28.510  5.785   151.132 1.00 40.96  ? 348 TYR C CE1 1 
ATOM   8120  C CE2 . TYR C 1 329 ? 27.712  8.023   150.822 1.00 42.30  ? 348 TYR C CE2 1 
ATOM   8121  C CZ  . TYR C 1 329 ? 28.655  7.140   151.316 1.00 41.62  ? 348 TYR C CZ  1 
ATOM   8122  O OH  . TYR C 1 329 ? 29.744  7.618   151.982 1.00 42.11  ? 348 TYR C OH  1 
ATOM   8123  N N   . PRO C 1 330 ? 21.924  5.377   148.986 1.00 44.54  ? 349 PRO C N   1 
ATOM   8124  C CA  . PRO C 1 330 ? 20.794  4.791   148.220 1.00 45.98  ? 349 PRO C CA  1 
ATOM   8125  C C   . PRO C 1 330 ? 21.203  4.154   146.909 1.00 43.88  ? 349 PRO C C   1 
ATOM   8126  O O   . PRO C 1 330 ? 20.644  3.129   146.511 1.00 44.77  ? 349 PRO C O   1 
ATOM   8127  C CB  . PRO C 1 330 ? 19.870  5.985   147.990 1.00 48.47  ? 349 PRO C CB  1 
ATOM   8128  C CG  . PRO C 1 330 ? 20.772  7.210   148.184 1.00 47.70  ? 349 PRO C CG  1 
ATOM   8129  C CD  . PRO C 1 330 ? 21.804  6.837   149.167 1.00 45.93  ? 349 PRO C CD  1 
ATOM   8130  N N   . GLU C 1 331 ? 22.167  4.732   146.228 1.00 44.92  ? 350 GLU C N   1 
ATOM   8131  C CA  . GLU C 1 331 ? 22.772  4.145   145.053 1.00 43.21  ? 350 GLU C CA  1 
ATOM   8132  C C   . GLU C 1 331 ? 23.045  2.641   145.201 1.00 42.59  ? 350 GLU C C   1 
ATOM   8133  O O   . GLU C 1 331 ? 23.009  1.890   144.226 1.00 42.99  ? 350 GLU C O   1 
ATOM   8134  C CB  . GLU C 1 331 ? 24.074  4.892   144.742 1.00 41.89  ? 350 GLU C CB  1 
ATOM   8135  C CG  . GLU C 1 331 ? 23.928  6.366   144.222 1.00 42.61  ? 350 GLU C CG  1 
ATOM   8136  C CD  . GLU C 1 331 ? 23.761  7.500   145.291 1.00 44.28  ? 350 GLU C CD  1 
ATOM   8137  O OE1 . GLU C 1 331 ? 23.739  7.266   146.526 1.00 44.50  ? 350 GLU C OE1 1 
ATOM   8138  O OE2 . GLU C 1 331 ? 23.645  8.681   144.847 1.00 45.54  ? 350 GLU C OE2 1 
ATOM   8139  N N   . PHE C 1 332 ? 23.370  2.211   146.413 1.00 42.71  ? 351 PHE C N   1 
ATOM   8140  C CA  . PHE C 1 332 ? 23.773  0.846   146.693 1.00 42.11  ? 351 PHE C CA  1 
ATOM   8141  C C   . PHE C 1 332 ? 22.587  -0.079  146.936 1.00 43.81  ? 351 PHE C C   1 
ATOM   8142  O O   . PHE C 1 332 ? 22.781  -1.284  147.076 1.00 43.70  ? 351 PHE C O   1 
ATOM   8143  C CB  . PHE C 1 332 ? 24.677  0.814   147.924 1.00 41.37  ? 351 PHE C CB  1 
ATOM   8144  C CG  . PHE C 1 332 ? 26.053  1.390   147.707 1.00 39.57  ? 351 PHE C CG  1 
ATOM   8145  C CD1 . PHE C 1 332 ? 26.501  1.727   146.457 1.00 38.45  ? 351 PHE C CD1 1 
ATOM   8146  C CD2 . PHE C 1 332 ? 26.895  1.589   148.781 1.00 39.63  ? 351 PHE C CD2 1 
ATOM   8147  C CE1 . PHE C 1 332 ? 27.764  2.248   146.269 1.00 37.44  ? 351 PHE C CE1 1 
ATOM   8148  C CE2 . PHE C 1 332 ? 28.147  2.116   148.608 1.00 38.28  ? 351 PHE C CE2 1 
ATOM   8149  C CZ  . PHE C 1 332 ? 28.588  2.437   147.348 1.00 37.19  ? 351 PHE C CZ  1 
ATOM   8150  N N   . ASP C 1 333 ? 21.391  0.479   147.065 1.00 42.10  ? 352 ASP C N   1 
ATOM   8151  C CA  . ASP C 1 333 ? 20.152  -0.249  147.183 1.00 44.61  ? 352 ASP C CA  1 
ATOM   8152  C C   . ASP C 1 333 ? 19.312  -0.182  145.917 1.00 45.81  ? 352 ASP C C   1 
ATOM   8153  O O   . ASP C 1 333 ? 18.280  -0.861  145.835 1.00 48.56  ? 352 ASP C O   1 
ATOM   8154  C CB  . ASP C 1 333 ? 19.343  0.308   148.361 1.00 47.35  ? 352 ASP C CB  1 
ATOM   8155  C CG  . ASP C 1 333 ? 20.015  0.051   149.698 1.00 47.45  ? 352 ASP C CG  1 
ATOM   8156  O OD1 . ASP C 1 333 ? 20.900  -0.835  149.790 1.00 45.88  ? 352 ASP C OD1 1 
ATOM   8157  O OD2 . ASP C 1 333 ? 19.633  0.725   150.677 1.00 49.58  ? 352 ASP C OD2 1 
ATOM   8158  N N   . LYS C 1 334 ? 19.717  0.600   144.949 1.00 45.64  ? 353 LYS C N   1 
ATOM   8159  C CA  . LYS C 1 334 ? 18.917  0.712   143.745 1.00 47.71  ? 353 LYS C CA  1 
ATOM   8160  C C   . LYS C 1 334 ? 19.131  -0.509  142.877 1.00 47.25  ? 353 LYS C C   1 
ATOM   8161  O O   . LYS C 1 334 ? 20.230  -1.077  142.866 1.00 45.08  ? 353 LYS C O   1 
ATOM   8162  C CB  . LYS C 1 334 ? 19.282  1.957   142.956 1.00 47.50  ? 353 LYS C CB  1 
ATOM   8163  C CG  . LYS C 1 334 ? 18.881  3.165   143.679 1.00 48.92  ? 353 LYS C CG  1 
ATOM   8164  C CD  . LYS C 1 334 ? 19.211  4.378   142.902 1.00 49.21  ? 353 LYS C CD  1 
ATOM   8165  C CE  . LYS C 1 334 ? 19.183  5.563   143.843 1.00 50.20  ? 353 LYS C CE  1 
ATOM   8166  N NZ  . LYS C 1 334 ? 17.753  5.938   144.113 1.00 53.83  ? 353 LYS C NZ  1 
ATOM   8167  N N   . PRO C 1 335 ? 18.092  -0.922  142.158 1.00 46.46  ? 354 PRO C N   1 
ATOM   8168  C CA  . PRO C 1 335 ? 18.270  -1.941  141.125 1.00 46.54  ? 354 PRO C CA  1 
ATOM   8169  C C   . PRO C 1 335 ? 19.347  -1.531  140.134 1.00 44.57  ? 354 PRO C C   1 
ATOM   8170  O O   . PRO C 1 335 ? 19.347  -0.400  139.618 1.00 44.74  ? 354 PRO C O   1 
ATOM   8171  C CB  . PRO C 1 335 ? 16.893  -2.010  140.473 1.00 50.55  ? 354 PRO C CB  1 
ATOM   8172  C CG  . PRO C 1 335 ? 15.959  -1.602  141.588 1.00 52.35  ? 354 PRO C CG  1 
ATOM   8173  C CD  . PRO C 1 335 ? 16.678  -0.518  142.307 1.00 49.69  ? 354 PRO C CD  1 
ATOM   8174  N N   . LEU C 1 336 ? 20.288  -2.451  139.888 1.00 46.41  ? 355 LEU C N   1 
ATOM   8175  C CA  . LEU C 1 336 ? 21.268  -2.314  138.805 1.00 45.12  ? 355 LEU C CA  1 
ATOM   8176  C C   . LEU C 1 336 ? 20.958  -3.306  137.686 1.00 47.07  ? 355 LEU C C   1 
ATOM   8177  O O   . LEU C 1 336 ? 20.594  -2.901  136.575 1.00 49.06  ? 355 LEU C O   1 
ATOM   8178  C CB  . LEU C 1 336 ? 22.677  -2.508  139.356 1.00 42.44  ? 355 LEU C CB  1 
ATOM   8179  C CG  . LEU C 1 336 ? 23.891  -2.429  138.428 1.00 41.29  ? 355 LEU C CG  1 
ATOM   8180  C CD1 . LEU C 1 336 ? 24.202  -1.083  137.888 1.00 40.91  ? 355 LEU C CD1 1 
ATOM   8181  C CD2 . LEU C 1 336 ? 25.084  -2.914  139.246 1.00 39.14  ? 355 LEU C CD2 1 
ATOM   8182  N N   . GLY C 1 337 ? 21.111  -4.604  137.930 1.00 45.74  ? 356 GLY C N   1 
ATOM   8183  C CA  . GLY C 1 337 ? 20.794  -5.606  136.943 1.00 47.86  ? 356 GLY C CA  1 
ATOM   8184  C C   . GLY C 1 337 ? 21.978  -5.960  136.063 1.00 47.03  ? 356 GLY C C   1 
ATOM   8185  O O   . GLY C 1 337 ? 23.033  -5.312  136.068 1.00 45.02  ? 356 GLY C O   1 
ATOM   8186  N N   . LYS C 1 338 ? 21.794  -7.029  135.290 1.00 46.81  ? 357 LYS C N   1 
ATOM   8187  C CA  . LYS C 1 338 ? 22.862  -7.465  134.402 1.00 47.08  ? 357 LYS C CA  1 
ATOM   8188  C C   . LYS C 1 338 ? 23.294  -6.304  133.498 1.00 47.35  ? 357 LYS C C   1 
ATOM   8189  O O   . LYS C 1 338 ? 22.451  -5.515  133.034 1.00 49.17  ? 357 LYS C O   1 
ATOM   8190  C CB  . LYS C 1 338 ? 22.412  -8.667  133.559 1.00 50.39  ? 357 LYS C CB  1 
ATOM   8191  N N   . PRO C 1 339 ? 24.589  -6.172  133.237 1.00 44.95  ? 358 PRO C N   1 
ATOM   8192  C CA  . PRO C 1 339 ? 25.021  -5.391  132.071 1.00 46.24  ? 358 PRO C CA  1 
ATOM   8193  C C   . PRO C 1 339 ? 24.285  -5.891  130.861 1.00 50.28  ? 358 PRO C C   1 
ATOM   8194  O O   . PRO C 1 339 ? 24.115  -7.101  130.695 1.00 51.35  ? 358 PRO C O   1 
ATOM   8195  C CB  . PRO C 1 339 ? 26.525  -5.654  131.979 1.00 45.18  ? 358 PRO C CB  1 
ATOM   8196  C CG  . PRO C 1 339 ? 26.875  -6.582  133.072 1.00 43.03  ? 358 PRO C CG  1 
ATOM   8197  C CD  . PRO C 1 339 ? 25.679  -6.868  133.953 1.00 43.04  ? 358 PRO C CD  1 
ATOM   8198  N N   . VAL C 1 340 ? 23.814  -4.954  130.045 1.00 48.71  ? 359 VAL C N   1 
ATOM   8199  C CA  . VAL C 1 340 ? 23.203  -5.307  128.772 1.00 51.55  ? 359 VAL C CA  1 
ATOM   8200  C C   . VAL C 1 340 ? 24.059  -4.866  127.597 1.00 52.32  ? 359 VAL C C   1 
ATOM   8201  O O   . VAL C 1 340 ? 23.634  -5.002  126.451 1.00 54.87  ? 359 VAL C O   1 
ATOM   8202  C CB  . VAL C 1 340 ? 21.773  -4.752  128.657 1.00 53.13  ? 359 VAL C CB  1 
ATOM   8203  C CG1 . VAL C 1 340 ? 20.894  -5.310  129.786 1.00 52.71  ? 359 VAL C CG1 1 
ATOM   8204  C CG2 . VAL C 1 340 ? 21.796  -3.222  128.666 1.00 52.32  ? 359 VAL C CG2 1 
ATOM   8205  N N   . GLY C 1 341 ? 25.255  -4.351  127.855 1.00 50.42  ? 360 GLY C N   1 
ATOM   8206  C CA  . GLY C 1 341 ? 26.233  -4.109  126.816 1.00 51.15  ? 360 GLY C CA  1 
ATOM   8207  C C   . GLY C 1 341 ? 27.621  -3.981  127.402 1.00 48.86  ? 360 GLY C C   1 
ATOM   8208  O O   . GLY C 1 341 ? 27.794  -3.794  128.617 1.00 46.67  ? 360 GLY C O   1 
ATOM   8209  N N   . GLU C 1 342 ? 28.613  -4.074  126.527 1.00 49.60  ? 361 GLU C N   1 
ATOM   8210  C CA  . GLU C 1 342 ? 29.991  -3.917  126.948 1.00 47.87  ? 361 GLU C CA  1 
ATOM   8211  C C   . GLU C 1 342 ? 30.346  -2.445  127.127 1.00 46.64  ? 361 GLU C C   1 
ATOM   8212  O O   . GLU C 1 342 ? 29.739  -1.545  126.527 1.00 47.62  ? 361 GLU C O   1 
ATOM   8213  C CB  . GLU C 1 342 ? 30.959  -4.499  125.927 1.00 49.45  ? 361 GLU C CB  1 
ATOM   8214  C CG  . GLU C 1 342 ? 30.731  -5.949  125.572 1.00 51.06  ? 361 GLU C CG  1 
ATOM   8215  C CD  . GLU C 1 342 ? 31.131  -6.918  126.680 1.00 49.71  ? 361 GLU C CD  1 
ATOM   8216  O OE1 . GLU C 1 342 ? 31.656  -6.499  127.758 1.00 47.41  ? 361 GLU C OE1 1 
ATOM   8217  O OE2 . GLU C 1 342 ? 30.894  -8.139  126.442 1.00 51.22  ? 361 GLU C OE2 1 
ATOM   8218  N N   . MET C 1 343 ? 31.359  -2.207  127.948 1.00 48.57  ? 362 MET C N   1 
ATOM   8219  C CA  . MET C 1 343 ? 31.847  -0.858  128.083 1.00 47.37  ? 362 MET C CA  1 
ATOM   8220  C C   . MET C 1 343 ? 32.205  -0.353  126.699 1.00 49.45  ? 362 MET C C   1 
ATOM   8221  O O   . MET C 1 343 ? 32.765  -1.095  125.884 1.00 51.44  ? 362 MET C O   1 
ATOM   8222  C CB  . MET C 1 343 ? 33.057  -0.787  128.994 1.00 45.88  ? 362 MET C CB  1 
ATOM   8223  C CG  . MET C 1 343 ? 33.425  0.651   129.304 1.00 44.29  ? 362 MET C CG  1 
ATOM   8224  S SD  . MET C 1 343 ? 34.902  0.749   130.321 1.00 43.25  ? 362 MET C SD  1 
ATOM   8225  C CE  . MET C 1 343 ? 36.115  0.226   129.099 1.00 46.60  ? 362 MET C CE  1 
ATOM   8226  N N   . VAL C 1 344 ? 31.844  0.912   126.442 1.00 46.06  ? 363 VAL C N   1 
ATOM   8227  C CA  . VAL C 1 344 ? 32.115  1.622   125.197 1.00 47.89  ? 363 VAL C CA  1 
ATOM   8228  C C   . VAL C 1 344 ? 32.985  2.835   125.518 1.00 46.74  ? 363 VAL C C   1 
ATOM   8229  O O   . VAL C 1 344 ? 32.771  3.519   126.523 1.00 44.47  ? 363 VAL C O   1 
ATOM   8230  C CB  . VAL C 1 344 ? 30.795  2.043   124.510 1.00 49.59  ? 363 VAL C CB  1 
ATOM   8231  C CG1 . VAL C 1 344 ? 31.035  2.953   123.296 1.00 51.65  ? 363 VAL C CG1 1 
ATOM   8232  C CG2 . VAL C 1 344 ? 30.004  0.797   124.162 1.00 50.86  ? 363 VAL C CG2 1 
ATOM   8233  N N   . ARG C 1 345 ? 33.978  3.084   124.664 1.00 47.98  ? 364 ARG C N   1 
ATOM   8234  C CA  . ARG C 1 345 ? 34.885  4.208   124.801 1.00 46.71  ? 364 ARG C CA  1 
ATOM   8235  C C   . ARG C 1 345 ? 34.914  5.065   123.532 1.00 49.52  ? 364 ARG C C   1 
ATOM   8236  O O   . ARG C 1 345 ? 34.897  4.547   122.406 1.00 51.77  ? 364 ARG C O   1 
ATOM   8237  C CB  . ARG C 1 345 ? 36.293  3.711   125.129 1.00 45.03  ? 364 ARG C CB  1 
ATOM   8238  C CG  . ARG C 1 345 ? 37.299  4.848   125.336 1.00 43.96  ? 364 ARG C CG  1 
ATOM   8239  C CD  . ARG C 1 345 ? 38.399  4.524   126.319 1.00 43.18  ? 364 ARG C CD  1 
ATOM   8240  N NE  . ARG C 1 345 ? 39.492  3.816   125.662 1.00 45.85  ? 364 ARG C NE  1 
ATOM   8241  C CZ  . ARG C 1 345 ? 40.433  4.387   124.932 1.00 48.01  ? 364 ARG C CZ  1 
ATOM   8242  N NH1 . ARG C 1 345 ? 40.457  5.690   124.751 1.00 47.91  ? 364 ARG C NH1 1 
ATOM   8243  N NH2 . ARG C 1 345 ? 41.370  3.628   124.366 1.00 50.02  ? 364 ARG C NH2 1 
ATOM   8244  N N   . ASP C 1 346 ? 34.901  6.395   123.736 1.00 48.78  ? 365 ASP C N   1 
ATOM   8245  C CA  . ASP C 1 346 ? 35.276  7.408   122.733 1.00 50.98  ? 365 ASP C CA  1 
ATOM   8246  C C   . ASP C 1 346 ? 36.269  8.292   123.511 1.00 48.63  ? 365 ASP C C   1 
ATOM   8247  O O   . ASP C 1 346 ? 35.848  9.197   124.246 1.00 47.39  ? 365 ASP C O   1 
ATOM   8248  C CB  . ASP C 1 346 ? 34.095  8.196   122.191 1.00 52.15  ? 365 ASP C CB  1 
ATOM   8249  N N   . GLY C 1 347 ? 37.569  7.969   123.431 1.00 48.89  ? 366 GLY C N   1 
ATOM   8250  C CA  . GLY C 1 347 ? 38.618  8.702   124.126 1.00 47.71  ? 366 GLY C CA  1 
ATOM   8251  C C   . GLY C 1 347 ? 38.722  8.487   125.623 1.00 45.12  ? 366 GLY C C   1 
ATOM   8252  O O   . GLY C 1 347 ? 39.076  7.405   126.081 1.00 44.98  ? 366 GLY C O   1 
ATOM   8253  N N   . TRP C 1 348 ? 38.460  9.521   126.413 1.00 45.33  ? 367 TRP C N   1 
ATOM   8254  C CA  . TRP C 1 348 ? 38.408  9.401   127.871 1.00 43.21  ? 367 TRP C CA  1 
ATOM   8255  C C   . TRP C 1 348 ? 36.981  9.216   128.354 1.00 41.39  ? 367 TRP C C   1 
ATOM   8256  O O   . TRP C 1 348 ? 36.745  9.181   129.562 1.00 39.56  ? 367 TRP C O   1 
ATOM   8257  C CB  . TRP C 1 348 ? 39.044  10.637  128.547 1.00 42.66  ? 367 TRP C CB  1 
ATOM   8258  C CG  . TRP C 1 348 ? 40.404  10.915  128.018 1.00 44.72  ? 367 TRP C CG  1 
ATOM   8259  C CD1 . TRP C 1 348 ? 40.787  11.927  127.191 1.00 46.11  ? 367 TRP C CD1 1 
ATOM   8260  C CD2 . TRP C 1 348 ? 41.563  10.134  128.262 1.00 45.90  ? 367 TRP C CD2 1 
ATOM   8261  N NE1 . TRP C 1 348 ? 42.121  11.818  126.905 1.00 48.36  ? 367 TRP C NE1 1 
ATOM   8262  C CE2 . TRP C 1 348 ? 42.617  10.716  127.549 1.00 48.11  ? 367 TRP C CE2 1 
ATOM   8263  C CE3 . TRP C 1 348 ? 41.810  8.973   129.011 1.00 45.48  ? 367 TRP C CE3 1 
ATOM   8264  C CZ2 . TRP C 1 348 ? 43.899  10.185  127.569 1.00 50.06  ? 367 TRP C CZ2 1 
ATOM   8265  C CZ3 . TRP C 1 348 ? 43.074  8.456   129.031 1.00 47.35  ? 367 TRP C CZ3 1 
ATOM   8266  C CH2 . TRP C 1 348 ? 44.105  9.057   128.316 1.00 49.61  ? 367 TRP C CH2 1 
ATOM   8267  N N   . LYS C 1 349 ? 36.025  9.131   127.429 1.00 47.52  ? 368 LYS C N   1 
ATOM   8268  C CA  . LYS C 1 349 ? 34.622  8.917   127.743 1.00 46.52  ? 368 LYS C CA  1 
ATOM   8269  C C   . LYS C 1 349 ? 34.287  7.428   127.747 1.00 46.06  ? 368 LYS C C   1 
ATOM   8270  O O   . LYS C 1 349 ? 34.581  6.704   126.781 1.00 48.20  ? 368 LYS C O   1 
ATOM   8271  C CB  . LYS C 1 349 ? 33.754  9.633   126.718 1.00 48.52  ? 368 LYS C CB  1 
ATOM   8272  C CG  . LYS C 1 349 ? 33.844  11.166  126.855 1.00 49.42  ? 368 LYS C CG  1 
ATOM   8273  C CD  . LYS C 1 349 ? 32.557  11.871  126.431 1.00 52.09  ? 368 LYS C CD  1 
ATOM   8274  C CE  . LYS C 1 349 ? 32.795  13.334  126.153 1.00 54.37  ? 368 LYS C CE  1 
ATOM   8275  N NZ  . LYS C 1 349 ? 34.080  13.568  125.440 1.00 55.66  ? 368 LYS C NZ  1 
ATOM   8276  N N   . LEU C 1 350 ? 33.634  6.983   128.811 1.00 45.14  ? 369 LEU C N   1 
ATOM   8277  C CA  . LEU C 1 350 ? 33.169  5.618   128.912 1.00 44.95  ? 369 LEU C CA  1 
ATOM   8278  C C   . LEU C 1 350 ? 31.663  5.624   129.120 1.00 44.82  ? 369 LEU C C   1 
ATOM   8279  O O   . LEU C 1 350 ? 31.118  6.535   129.750 1.00 43.84  ? 369 LEU C O   1 
ATOM   8280  C CB  . LEU C 1 350 ? 33.875  4.909   130.035 1.00 43.91  ? 369 LEU C CB  1 
ATOM   8281  C CG  . LEU C 1 350 ? 35.394  5.043   130.094 1.00 44.72  ? 369 LEU C CG  1 
ATOM   8282  C CD1 . LEU C 1 350 ? 35.870  4.506   131.455 1.00 43.34  ? 369 LEU C CD1 1 
ATOM   8283  C CD2 . LEU C 1 350 ? 36.068  4.317   128.962 1.00 47.43  ? 369 LEU C CD2 1 
ATOM   8284  N N   . SER C 1 351 ? 30.987  4.615   128.541 1.00 45.72  ? 370 SER C N   1 
ATOM   8285  C CA  . SER C 1 351 ? 29.605  4.348   128.896 1.00 45.97  ? 370 SER C CA  1 
ATOM   8286  C C   . SER C 1 351 ? 29.371  2.851   129.026 1.00 46.07  ? 370 SER C C   1 
ATOM   8287  O O   . SER C 1 351 ? 30.114  2.014   128.497 1.00 47.06  ? 370 SER C O   1 
ATOM   8288  C CB  . SER C 1 351 ? 28.610  4.948   127.907 1.00 48.33  ? 370 SER C CB  1 
ATOM   8289  O OG  . SER C 1 351 ? 28.680  4.266   126.682 1.00 51.19  ? 370 SER C OG  1 
ATOM   8290  N N   . ARG C 1 352 ? 28.322  2.540   129.777 1.00 45.22  ? 371 ARG C N   1 
ATOM   8291  C CA  . ARG C 1 352 ? 27.906  1.176   130.043 1.00 45.73  ? 371 ARG C CA  1 
ATOM   8292  C C   . ARG C 1 352 ? 26.411  1.222   130.316 1.00 46.42  ? 371 ARG C C   1 
ATOM   8293  O O   . ARG C 1 352 ? 25.917  2.173   130.951 1.00 45.62  ? 371 ARG C O   1 
ATOM   8294  C CB  . ARG C 1 352 ? 28.660  0.583   131.241 1.00 44.04  ? 371 ARG C CB  1 
ATOM   8295  C CG  . ARG C 1 352 ? 28.509  -0.917  131.391 1.00 44.42  ? 371 ARG C CG  1 
ATOM   8296  C CD  . ARG C 1 352 ? 29.372  -1.649  130.366 1.00 46.27  ? 371 ARG C CD  1 
ATOM   8297  N NE  . ARG C 1 352 ? 29.440  -3.079  130.656 1.00 46.77  ? 371 ARG C NE  1 
ATOM   8298  C CZ  . ARG C 1 352 ? 30.127  -3.629  131.655 1.00 44.81  ? 371 ARG C CZ  1 
ATOM   8299  N NH1 . ARG C 1 352 ? 30.813  -2.891  132.524 1.00 42.50  ? 371 ARG C NH1 1 
ATOM   8300  N NH2 . ARG C 1 352 ? 30.138  -4.953  131.775 1.00 45.61  ? 371 ARG C NH2 1 
ATOM   8301  N N   . GLU C 1 353 ? 25.712  0.206   129.826 1.00 48.33  ? 372 GLU C N   1 
ATOM   8302  C CA  . GLU C 1 353 ? 24.293  -0.004  130.062 1.00 49.71  ? 372 GLU C CA  1 
ATOM   8303  C C   . GLU C 1 353 ? 24.067  -1.251  130.927 1.00 49.65  ? 372 GLU C C   1 
ATOM   8304  O O   . GLU C 1 353 ? 24.754  -2.264  130.784 1.00 50.07  ? 372 GLU C O   1 
ATOM   8305  C CB  . GLU C 1 353 ? 23.551  -0.144  128.726 1.00 53.10  ? 372 GLU C CB  1 
ATOM   8306  C CG  . GLU C 1 353 ? 23.851  0.991   127.761 1.00 54.55  ? 372 GLU C CG  1 
ATOM   8307  C CD  . GLU C 1 353 ? 23.426  2.394   128.322 1.00 54.38  ? 372 GLU C CD  1 
ATOM   8308  O OE1 . GLU C 1 353 ? 22.278  2.506   128.840 1.00 54.89  ? 372 GLU C OE1 1 
ATOM   8309  O OE2 . GLU C 1 353 ? 24.242  3.390   128.218 1.00 53.98  ? 372 GLU C OE2 1 
ATOM   8310  N N   . TYR C 1 354 ? 23.087  -1.143  131.829 1.00 49.18  ? 373 TYR C N   1 
ATOM   8311  C CA  . TYR C 1 354 ? 22.665  -2.177  132.760 1.00 49.45  ? 373 TYR C CA  1 
ATOM   8312  C C   . TYR C 1 354 ? 21.153  -2.288  132.636 1.00 52.25  ? 373 TYR C C   1 
ATOM   8313  O O   . TYR C 1 354 ? 20.500  -1.361  132.151 1.00 53.64  ? 373 TYR C O   1 
ATOM   8314  C CB  . TYR C 1 354 ? 23.043  -1.814  134.200 1.00 46.43  ? 373 TYR C CB  1 
ATOM   8315  C CG  . TYR C 1 354 ? 24.507  -1.919  134.478 1.00 43.74  ? 373 TYR C CG  1 
ATOM   8316  C CD1 . TYR C 1 354 ? 25.392  -0.935  134.077 1.00 42.61  ? 373 TYR C CD1 1 
ATOM   8317  C CD2 . TYR C 1 354 ? 25.006  -3.012  135.156 1.00 42.73  ? 373 TYR C CD2 1 
ATOM   8318  C CE1 . TYR C 1 354 ? 26.746  -1.058  134.345 1.00 40.97  ? 373 TYR C CE1 1 
ATOM   8319  C CE2 . TYR C 1 354 ? 26.346  -3.129  135.442 1.00 41.04  ? 373 TYR C CE2 1 
ATOM   8320  C CZ  . TYR C 1 354 ? 27.215  -2.163  135.042 1.00 39.93  ? 373 TYR C CZ  1 
ATOM   8321  O OH  . TYR C 1 354 ? 28.540  -2.338  135.323 1.00 38.76  ? 373 TYR C OH  1 
ATOM   8322  N N   . LYS C 1 355 ? 20.568  -3.401  133.092 1.00 51.08  ? 374 LYS C N   1 
ATOM   8323  C CA  . LYS C 1 355 ? 19.117  -3.510  132.947 1.00 52.39  ? 374 LYS C CA  1 
ATOM   8324  C C   . LYS C 1 355 ? 18.436  -2.241  133.469 1.00 51.53  ? 374 LYS C C   1 
ATOM   8325  O O   . LYS C 1 355 ? 17.630  -1.618  132.771 1.00 52.64  ? 374 LYS C O   1 
ATOM   8326  C CB  . LYS C 1 355 ? 18.567  -4.747  133.652 1.00 53.27  ? 374 LYS C CB  1 
ATOM   8327  N N   . HIS C 1 356 ? 18.816  -1.787  134.656 1.00 51.97  ? 375 HIS C N   1 
ATOM   8328  C CA  . HIS C 1 356 ? 18.121  -0.694  135.320 1.00 51.52  ? 375 HIS C CA  1 
ATOM   8329  C C   . HIS C 1 356 ? 18.952  0.557   135.505 1.00 50.25  ? 375 HIS C C   1 
ATOM   8330  O O   . HIS C 1 356 ? 18.620  1.372   136.375 1.00 49.89  ? 375 HIS C O   1 
ATOM   8331  C CB  . HIS C 1 356 ? 17.643  -1.185  136.674 1.00 51.34  ? 375 HIS C CB  1 
ATOM   8332  C CG  . HIS C 1 356 ? 16.887  -2.449  136.573 1.00 52.62  ? 375 HIS C CG  1 
ATOM   8333  N ND1 . HIS C 1 356 ? 15.681  -2.516  135.925 1.00 54.42  ? 375 HIS C ND1 1 
ATOM   8334  C CD2 . HIS C 1 356 ? 17.195  -3.714  136.937 1.00 52.95  ? 375 HIS C CD2 1 
ATOM   8335  C CE1 . HIS C 1 356 ? 15.249  -3.763  135.934 1.00 55.19  ? 375 HIS C CE1 1 
ATOM   8336  N NE2 . HIS C 1 356 ? 16.146  -4.507  136.555 1.00 54.52  ? 375 HIS C NE2 1 
ATOM   8337  N N   . ALA C 1 357 ? 20.015  0.739   134.723 1.00 51.85  ? 376 ALA C N   1 
ATOM   8338  C CA  . ALA C 1 357 ? 20.859  1.911   134.917 1.00 50.79  ? 376 ALA C CA  1 
ATOM   8339  C C   . ALA C 1 357 ? 21.726  2.174   133.698 1.00 51.69  ? 376 ALA C C   1 
ATOM   8340  O O   . ALA C 1 357 ? 22.144  1.239   133.010 1.00 51.83  ? 376 ALA C O   1 
ATOM   8341  C CB  . ALA C 1 357 ? 21.771  1.753   136.137 1.00 49.03  ? 376 ALA C CB  1 
ATOM   8342  N N   . SER C 1 358 ? 22.045  3.469   133.487 1.00 50.76  ? 377 SER C N   1 
ATOM   8343  C CA  . SER C 1 358 ? 22.921  3.925   132.418 1.00 51.10  ? 377 SER C CA  1 
ATOM   8344  C C   . SER C 1 358 ? 24.055  4.751   133.008 1.00 49.24  ? 377 SER C C   1 
ATOM   8345  O O   . SER C 1 358 ? 23.828  5.622   133.851 1.00 48.04  ? 377 SER C O   1 
ATOM   8346  C CB  . SER C 1 358 ? 22.162  4.780   131.391 1.00 53.17  ? 377 SER C CB  1 
ATOM   8347  O OG  . SER C 1 358 ? 21.154  4.019   130.727 1.00 55.58  ? 377 SER C OG  1 
ATOM   8348  N N   . VAL C 1 359 ? 25.275  4.502   132.531 1.00 47.47  ? 378 VAL C N   1 
ATOM   8349  C CA  . VAL C 1 359 ? 26.490  5.014   133.158 1.00 45.96  ? 378 VAL C CA  1 
ATOM   8350  C C   . VAL C 1 359 ? 27.315  5.684   132.084 1.00 46.60  ? 378 VAL C C   1 
ATOM   8351  O O   . VAL C 1 359 ? 27.582  5.076   131.049 1.00 47.32  ? 378 VAL C O   1 
ATOM   8352  C CB  . VAL C 1 359 ? 27.332  3.882   133.814 1.00 45.15  ? 378 VAL C CB  1 
ATOM   8353  C CG1 . VAL C 1 359 ? 28.579  4.448   134.478 1.00 44.11  ? 378 VAL C CG1 1 
ATOM   8354  C CG2 . VAL C 1 359 ? 26.531  3.061   134.824 1.00 45.41  ? 378 VAL C CG2 1 
ATOM   8355  N N   . ARG C 1 360 ? 27.716  6.923   132.327 1.00 47.70  ? 379 ARG C N   1 
ATOM   8356  C CA  . ARG C 1 360 ? 28.555  7.715   131.437 1.00 48.49  ? 379 ARG C CA  1 
ATOM   8357  C C   . ARG C 1 360 ? 29.594  8.363   132.330 1.00 45.75  ? 379 ARG C C   1 
ATOM   8358  O O   . ARG C 1 360 ? 29.233  8.906   133.378 1.00 44.56  ? 379 ARG C O   1 
ATOM   8359  C CB  . ARG C 1 360 ? 27.760  8.800   130.719 1.00 50.83  ? 379 ARG C CB  1 
ATOM   8360  C CG  . ARG C 1 360 ? 27.572  8.612   129.217 1.00 55.15  ? 379 ARG C CG  1 
ATOM   8361  C CD  . ARG C 1 360 ? 26.230  7.974   128.842 1.00 58.12  ? 379 ARG C CD  1 
ATOM   8362  N NE  . ARG C 1 360 ? 26.282  7.400   127.493 1.00 61.17  ? 379 ARG C NE  1 
ATOM   8363  C CZ  . ARG C 1 360 ? 25.441  6.480   127.022 1.00 63.19  ? 379 ARG C CZ  1 
ATOM   8364  N NH1 . ARG C 1 360 ? 24.433  6.020   127.758 1.00 62.75  ? 379 ARG C NH1 1 
ATOM   8365  N NH2 . ARG C 1 360 ? 25.614  6.012   125.784 1.00 65.21  ? 379 ARG C NH2 1 
ATOM   8366  N N   . VAL C 1 361 ? 30.857  8.352   131.921 1.00 45.87  ? 380 VAL C N   1 
ATOM   8367  C CA  . VAL C 1 361 ? 31.924  8.966   132.710 1.00 43.76  ? 380 VAL C CA  1 
ATOM   8368  C C   . VAL C 1 361 ? 32.936  9.575   131.765 1.00 44.78  ? 380 VAL C C   1 
ATOM   8369  O O   . VAL C 1 361 ? 33.225  9.011   130.705 1.00 47.08  ? 380 VAL C O   1 
ATOM   8370  C CB  . VAL C 1 361 ? 32.565  7.930   133.654 1.00 42.91  ? 380 VAL C CB  1 
ATOM   8371  C CG1 . VAL C 1 361 ? 33.146  6.847   132.887 1.00 44.45  ? 380 VAL C CG1 1 
ATOM   8372  C CG2 . VAL C 1 361 ? 33.653  8.513   134.443 1.00 41.89  ? 380 VAL C CG2 1 
ATOM   8373  N N   . ASP C 1 362 ? 33.454  10.754  132.127 1.00 43.46  ? 381 ASP C N   1 
ATOM   8374  C CA  . ASP C 1 362 ? 34.543  11.386  131.384 1.00 44.14  ? 381 ASP C CA  1 
ATOM   8375  C C   . ASP C 1 362 ? 35.760  11.431  132.286 1.00 41.78  ? 381 ASP C C   1 
ATOM   8376  O O   . ASP C 1 362 ? 35.780  12.184  133.259 1.00 40.96  ? 381 ASP C O   1 
ATOM   8377  C CB  . ASP C 1 362 ? 34.189  12.792  130.904 1.00 44.73  ? 381 ASP C CB  1 
ATOM   8378  C CG  . ASP C 1 362 ? 35.228  13.353  129.930 1.00 46.36  ? 381 ASP C CG  1 
ATOM   8379  O OD1 . ASP C 1 362 ? 36.446  13.136  130.121 1.00 45.64  ? 381 ASP C OD1 1 
ATOM   8380  O OD2 . ASP C 1 362 ? 34.819  13.973  128.931 1.00 48.63  ? 381 ASP C OD2 1 
ATOM   8381  N N   . LEU C 1 363 ? 36.769  10.638  131.957 1.00 45.59  ? 382 LEU C N   1 
ATOM   8382  C CA  . LEU C 1 363 ? 37.920  10.512  132.839 1.00 43.30  ? 382 LEU C CA  1 
ATOM   8383  C C   . LEU C 1 363 ? 38.746  11.793  132.883 1.00 43.49  ? 382 LEU C C   1 
ATOM   8384  O O   . LEU C 1 363 ? 39.445  12.033  133.870 1.00 42.53  ? 382 LEU C O   1 
ATOM   8385  C CB  . LEU C 1 363 ? 38.779  9.339   132.388 1.00 42.92  ? 382 LEU C CB  1 
ATOM   8386  C CG  . LEU C 1 363 ? 38.124  7.968   132.454 1.00 42.73  ? 382 LEU C CG  1 
ATOM   8387  C CD1 . LEU C 1 363 ? 39.057  6.855   131.969 1.00 42.67  ? 382 LEU C CD1 1 
ATOM   8388  C CD2 . LEU C 1 363 ? 37.665  7.692   133.866 1.00 41.97  ? 382 LEU C CD2 1 
ATOM   8389  N N   . GLU C 1 364 ? 38.639  12.639  131.861 1.00 44.33  ? 383 GLU C N   1 
ATOM   8390  C CA  . GLU C 1 364 ? 39.479  13.832  131.742 1.00 44.51  ? 383 GLU C CA  1 
ATOM   8391  C C   . GLU C 1 364 ? 38.938  15.008  132.534 1.00 43.58  ? 383 GLU C C   1 
ATOM   8392  O O   . GLU C 1 364 ? 39.729  15.821  133.060 1.00 43.13  ? 383 GLU C O   1 
ATOM   8393  C CB  . GLU C 1 364 ? 39.605  14.190  130.258 1.00 47.20  ? 383 GLU C CB  1 
ATOM   8394  C CG  . GLU C 1 364 ? 40.228  15.499  129.976 1.00 47.86  ? 383 GLU C CG  1 
ATOM   8395  C CD  . GLU C 1 364 ? 40.487  15.726  128.519 1.00 50.77  ? 383 GLU C CD  1 
ATOM   8396  O OE1 . GLU C 1 364 ? 39.683  15.338  127.644 1.00 52.07  ? 383 GLU C OE1 1 
ATOM   8397  O OE2 . GLU C 1 364 ? 41.526  16.313  128.251 1.00 51.38  ? 383 GLU C OE2 1 
ATOM   8398  N N   . SER C 1 365 ? 37.611  15.148  132.614 1.00 44.28  ? 384 SER C N   1 
ATOM   8399  C CA  . SER C 1 365 ? 37.044  16.167  133.504 1.00 43.89  ? 384 SER C CA  1 
ATOM   8400  C C   . SER C 1 365 ? 36.637  15.595  134.856 1.00 43.22  ? 384 SER C C   1 
ATOM   8401  O O   . SER C 1 365 ? 36.394  16.369  135.788 1.00 43.16  ? 384 SER C O   1 
ATOM   8402  C CB  . SER C 1 365 ? 35.815  16.835  132.863 1.00 44.95  ? 384 SER C CB  1 
ATOM   8403  O OG  . SER C 1 365 ? 34.835  15.831  132.536 1.00 44.91  ? 384 SER C OG  1 
ATOM   8404  N N   . LYS C 1 366 ? 36.551  14.250  134.964 1.00 41.75  ? 385 LYS C N   1 
ATOM   8405  C CA  . LYS C 1 366 ? 36.122  13.558  136.173 1.00 41.72  ? 385 LYS C CA  1 
ATOM   8406  C C   . LYS C 1 366 ? 34.625  13.676  136.381 1.00 41.96  ? 385 LYS C C   1 
ATOM   8407  O O   . LYS C 1 366 ? 34.151  13.605  137.528 1.00 42.46  ? 385 LYS C O   1 
ATOM   8408  C CB  . LYS C 1 366 ? 36.807  14.118  137.411 1.00 42.57  ? 385 LYS C CB  1 
ATOM   8409  C CG  . LYS C 1 366 ? 37.527  13.160  138.287 1.00 43.58  ? 385 LYS C CG  1 
ATOM   8410  C CD  . LYS C 1 366 ? 38.967  13.209  137.896 1.00 43.94  ? 385 LYS C CD  1 
ATOM   8411  C CE  . LYS C 1 366 ? 39.851  12.504  138.854 1.00 44.56  ? 385 LYS C CE  1 
ATOM   8412  N NZ  . LYS C 1 366 ? 41.210  12.876  138.456 1.00 44.51  ? 385 LYS C NZ  1 
ATOM   8413  N N   . GLU C 1 367 ? 33.870  13.926  135.301 1.00 42.68  ? 386 GLU C N   1 
ATOM   8414  C CA  . GLU C 1 367 ? 32.418  14.035  135.375 1.00 43.58  ? 386 GLU C CA  1 
ATOM   8415  C C   . GLU C 1 367 ? 31.756  12.698  135.062 1.00 43.22  ? 386 GLU C C   1 
ATOM   8416  O O   . GLU C 1 367 ? 32.314  11.853  134.347 1.00 42.63  ? 386 GLU C O   1 
ATOM   8417  C CB  . GLU C 1 367 ? 31.913  15.101  134.405 1.00 45.66  ? 386 GLU C CB  1 
ATOM   8418  C CG  . GLU C 1 367 ? 32.270  16.535  134.750 1.00 47.22  ? 386 GLU C CG  1 
ATOM   8419  C CD  . GLU C 1 367 ? 31.777  17.514  133.660 1.00 49.91  ? 386 GLU C CD  1 
ATOM   8420  O OE1 . GLU C 1 367 ? 32.183  17.362  132.477 1.00 50.72  ? 386 GLU C OE1 1 
ATOM   8421  O OE2 . GLU C 1 367 ? 30.978  18.430  133.976 1.00 51.50  ? 386 GLU C OE2 1 
ATOM   8422  N N   . ALA C 1 368 ? 30.559  12.504  135.608 1.00 41.70  ? 387 ALA C N   1 
ATOM   8423  C CA  . ALA C 1 368 ? 29.923  11.200  135.567 1.00 41.55  ? 387 ALA C CA  1 
ATOM   8424  C C   . ALA C 1 368 ? 28.435  11.400  135.713 1.00 42.69  ? 387 ALA C C   1 
ATOM   8425  O O   . ALA C 1 368 ? 27.998  12.368  136.323 1.00 43.61  ? 387 ALA C O   1 
ATOM   8426  C CB  . ALA C 1 368 ? 30.447  10.296  136.686 1.00 41.03  ? 387 ALA C CB  1 
ATOM   8427  N N   . GLU C 1 369 ? 27.658  10.470  135.151 1.00 43.69  ? 388 GLU C N   1 
ATOM   8428  C CA  . GLU C 1 369 ? 26.208  10.496  135.255 1.00 44.88  ? 388 GLU C CA  1 
ATOM   8429  C C   . GLU C 1 369 ? 25.781  9.070   135.505 1.00 44.63  ? 388 GLU C C   1 
ATOM   8430  O O   . GLU C 1 369 ? 26.397  8.130   134.992 1.00 44.00  ? 388 GLU C O   1 
ATOM   8431  C CB  . GLU C 1 369 ? 25.529  11.043  134.011 1.00 46.95  ? 388 GLU C CB  1 
ATOM   8432  N N   . ILE C 1 370 ? 24.739  8.899   136.311 1.00 46.45  ? 389 ILE C N   1 
ATOM   8433  C CA  . ILE C 1 370 ? 24.138  7.591   136.482 1.00 46.82  ? 389 ILE C CA  1 
ATOM   8434  C C   . ILE C 1 370 ? 22.627  7.770   136.461 1.00 48.52  ? 389 ILE C C   1 
ATOM   8435  O O   . ILE C 1 370 ? 22.046  8.368   137.371 1.00 48.67  ? 389 ILE C O   1 
ATOM   8436  C CB  . ILE C 1 370 ? 24.617  6.905   137.760 1.00 45.97  ? 389 ILE C CB  1 
ATOM   8437  C CG1 . ILE C 1 370 ? 26.156  6.786   137.663 1.00 44.92  ? 389 ILE C CG1 1 
ATOM   8438  C CG2 . ILE C 1 370 ? 23.991  5.501   137.923 1.00 46.19  ? 389 ILE C CG2 1 
ATOM   8439  C CD1 . ILE C 1 370 ? 26.839  6.072   138.866 1.00 44.69  ? 389 ILE C CD1 1 
ATOM   8440  N N   . ARG C 1 371 ? 22.005  7.294   135.402 1.00 47.33  ? 390 ARG C N   1 
ATOM   8441  C CA  . ARG C 1 371 ? 20.562  7.255   135.255 1.00 48.90  ? 390 ARG C CA  1 
ATOM   8442  C C   . ARG C 1 371 ? 20.073  5.875   135.699 1.00 48.89  ? 390 ARG C C   1 
ATOM   8443  O O   . ARG C 1 371 ? 20.331  4.873   135.032 1.00 49.93  ? 390 ARG C O   1 
ATOM   8444  C CB  . ARG C 1 371 ? 20.194  7.538   133.808 1.00 52.09  ? 390 ARG C CB  1 
ATOM   8445  C CG  . ARG C 1 371 ? 19.134  8.577   133.633 1.00 55.36  ? 390 ARG C CG  1 
ATOM   8446  C CD  . ARG C 1 371 ? 19.791  9.922   133.524 1.00 55.50  ? 390 ARG C CD  1 
ATOM   8447  N NE  . ARG C 1 371 ? 18.935  11.009  133.980 1.00 58.60  ? 390 ARG C NE  1 
ATOM   8448  C CZ  . ARG C 1 371 ? 19.360  12.259  134.147 1.00 59.47  ? 390 ARG C CZ  1 
ATOM   8449  N NH1 . ARG C 1 371 ? 20.638  12.586  133.956 1.00 57.67  ? 390 ARG C NH1 1 
ATOM   8450  N NH2 . ARG C 1 371 ? 18.488  13.208  134.522 1.00 61.60  ? 390 ARG C NH2 1 
ATOM   8451  N N   . TRP C 1 372 ? 19.458  5.826   136.878 1.00 49.58  ? 391 TRP C N   1 
ATOM   8452  C CA  . TRP C 1 372 ? 18.656  4.703   137.309 1.00 50.00  ? 391 TRP C CA  1 
ATOM   8453  C C   . TRP C 1 372 ? 17.293  4.784   136.637 1.00 52.82  ? 391 TRP C C   1 
ATOM   8454  O O   . TRP C 1 372 ? 16.758  5.872   136.425 1.00 53.71  ? 391 TRP C O   1 
ATOM   8455  C CB  . TRP C 1 372 ? 18.531  4.745   138.822 1.00 49.33  ? 391 TRP C CB  1 
ATOM   8456  C CG  . TRP C 1 372 ? 19.835  4.923   139.477 1.00 48.18  ? 391 TRP C CG  1 
ATOM   8457  C CD1 . TRP C 1 372 ? 20.403  6.092   139.848 1.00 48.10  ? 391 TRP C CD1 1 
ATOM   8458  C CD2 . TRP C 1 372 ? 20.771  3.896   139.844 1.00 47.27  ? 391 TRP C CD2 1 
ATOM   8459  N NE1 . TRP C 1 372 ? 21.629  5.871   140.427 1.00 47.16  ? 391 TRP C NE1 1 
ATOM   8460  C CE2 . TRP C 1 372 ? 21.877  4.526   140.431 1.00 46.68  ? 391 TRP C CE2 1 
ATOM   8461  C CE3 . TRP C 1 372 ? 20.781  2.519   139.730 1.00 47.21  ? 391 TRP C CE3 1 
ATOM   8462  C CZ2 . TRP C 1 372 ? 22.970  3.818   140.905 1.00 46.08  ? 391 TRP C CZ2 1 
ATOM   8463  C CZ3 . TRP C 1 372 ? 21.862  1.831   140.177 1.00 46.65  ? 391 TRP C CZ3 1 
ATOM   8464  C CH2 . TRP C 1 372 ? 22.939  2.468   140.767 1.00 46.11  ? 391 TRP C CH2 1 
ATOM   8465  N N   . ARG C 1 373 ? 16.733  3.636   136.279 1.00 51.89  ? 392 ARG C N   1 
ATOM   8466  C CA  . ARG C 1 373 ? 15.432  3.627   135.631 1.00 53.77  ? 392 ARG C CA  1 
ATOM   8467  C C   . ARG C 1 373 ? 14.642  2.417   136.078 1.00 54.18  ? 392 ARG C C   1 
ATOM   8468  O O   . ARG C 1 373 ? 15.243  1.495   136.621 1.00 53.07  ? 392 ARG C O   1 
ATOM   8469  C CB  . ARG C 1 373 ? 15.597  3.612   134.119 1.00 56.34  ? 392 ARG C CB  1 
ATOM   8470  C CG  . ARG C 1 373 ? 16.546  2.550   133.646 1.00 57.94  ? 392 ARG C CG  1 
ATOM   8471  C CD  . ARG C 1 373 ? 16.672  2.495   132.127 1.00 60.75  ? 392 ARG C CD  1 
ATOM   8472  N NE  . ARG C 1 373 ? 17.750  1.578   131.758 1.00 60.97  ? 392 ARG C NE  1 
ATOM   8473  C CZ  . ARG C 1 373 ? 18.784  1.909   130.986 1.00 60.85  ? 392 ARG C CZ  1 
ATOM   8474  N NH1 . ARG C 1 373 ? 18.833  3.090   130.365 1.00 60.78  ? 392 ARG C NH1 1 
ATOM   8475  N NH2 . ARG C 1 373 ? 19.785  1.034   130.823 1.00 60.42  ? 392 ARG C NH2 1 
ATOM   8476  N N   . GLU D 1 18  ? 57.951  -50.757 116.497 1.00 57.58  ? 37  GLU D N   1 
ATOM   8477  C CA  . GLU D 1 18  ? 59.147  -51.571 116.663 1.00 58.66  ? 37  GLU D CA  1 
ATOM   8478  C C   . GLU D 1 18  ? 60.227  -50.742 117.370 1.00 58.13  ? 37  GLU D C   1 
ATOM   8479  O O   . GLU D 1 18  ? 60.162  -50.518 118.581 1.00 56.72  ? 37  GLU D O   1 
ATOM   8480  C CB  . GLU D 1 18  ? 59.631  -52.091 115.299 1.00 61.12  ? 37  GLU D CB  1 
ATOM   8481  N N   . SER D 1 19  ? 61.188  -50.258 116.573 1.00 59.76  ? 38  SER D N   1 
ATOM   8482  C CA  . SER D 1 19  ? 62.448  -49.696 117.062 1.00 60.41  ? 38  SER D CA  1 
ATOM   8483  C C   . SER D 1 19  ? 62.347  -48.247 117.524 1.00 59.13  ? 38  SER D C   1 
ATOM   8484  O O   . SER D 1 19  ? 63.213  -47.799 118.287 1.00 60.43  ? 38  SER D O   1 
ATOM   8485  C CB  . SER D 1 19  ? 63.497  -49.783 115.946 1.00 63.06  ? 38  SER D CB  1 
ATOM   8486  O OG  . SER D 1 19  ? 62.862  -49.738 114.668 1.00 63.30  ? 38  SER D OG  1 
ATOM   8487  N N   . HIS D 1 20  ? 61.327  -47.502 117.066 1.00 58.45  ? 39  HIS D N   1 
ATOM   8488  C CA  . HIS D 1 20  ? 61.138  -46.097 117.419 1.00 58.39  ? 39  HIS D CA  1 
ATOM   8489  C C   . HIS D 1 20  ? 60.467  -45.914 118.776 1.00 57.05  ? 39  HIS D C   1 
ATOM   8490  O O   . HIS D 1 20  ? 60.177  -44.769 119.145 1.00 57.50  ? 39  HIS D O   1 
ATOM   8491  C CB  . HIS D 1 20  ? 60.308  -45.411 116.326 1.00 58.25  ? 39  HIS D CB  1 
ATOM   8492  N N   . TYR D 1 21  ? 60.209  -46.999 119.519 1.00 55.81  ? 40  TYR D N   1 
ATOM   8493  C CA  . TYR D 1 21  ? 59.492  -46.928 120.786 1.00 55.17  ? 40  TYR D CA  1 
ATOM   8494  C C   . TYR D 1 21  ? 60.446  -46.499 121.905 1.00 56.60  ? 40  TYR D C   1 
ATOM   8495  O O   . TYR D 1 21  ? 61.667  -46.628 121.765 1.00 57.81  ? 40  TYR D O   1 
ATOM   8496  C CB  . TYR D 1 21  ? 58.912  -48.298 121.156 1.00 53.79  ? 40  TYR D CB  1 
ATOM   8497  C CG  . TYR D 1 21  ? 57.630  -48.794 120.479 1.00 51.62  ? 40  TYR D CG  1 
ATOM   8498  C CD1 . TYR D 1 21  ? 57.040  -48.104 119.416 1.00 51.18  ? 40  TYR D CD1 1 
ATOM   8499  C CD2 . TYR D 1 21  ? 57.012  -49.969 120.919 1.00 50.23  ? 40  TYR D CD2 1 
ATOM   8500  C CE1 . TYR D 1 21  ? 55.869  -48.569 118.817 1.00 49.01  ? 40  TYR D CE1 1 
ATOM   8501  C CE2 . TYR D 1 21  ? 55.850  -50.434 120.330 1.00 48.31  ? 40  TYR D CE2 1 
ATOM   8502  C CZ  . TYR D 1 21  ? 55.282  -49.736 119.272 1.00 47.34  ? 40  TYR D CZ  1 
ATOM   8503  O OH  . TYR D 1 21  ? 54.120  -50.196 118.679 1.00 45.61  ? 40  TYR D OH  1 
ATOM   8504  N N   . PRO D 1 22  ? 59.918  -46.045 123.049 1.00 52.83  ? 41  PRO D N   1 
ATOM   8505  C CA  . PRO D 1 22  ? 60.784  -45.797 124.220 1.00 53.68  ? 41  PRO D CA  1 
ATOM   8506  C C   . PRO D 1 22  ? 61.368  -47.088 124.785 1.00 53.44  ? 41  PRO D C   1 
ATOM   8507  O O   . PRO D 1 22  ? 60.643  -48.051 125.034 1.00 52.62  ? 41  PRO D O   1 
ATOM   8508  C CB  . PRO D 1 22  ? 59.845  -45.125 125.235 1.00 53.41  ? 41  PRO D CB  1 
ATOM   8509  C CG  . PRO D 1 22  ? 58.662  -44.754 124.510 1.00 53.28  ? 41  PRO D CG  1 
ATOM   8510  C CD  . PRO D 1 22  ? 58.526  -45.668 123.328 1.00 52.25  ? 41  PRO D CD  1 
ATOM   8511  N N   . GLU D 1 23  ? 62.673  -47.084 125.029 1.00 52.64  ? 42  GLU D N   1 
ATOM   8512  C CA  . GLU D 1 23  ? 63.335  -48.229 125.638 1.00 52.66  ? 42  GLU D CA  1 
ATOM   8513  C C   . GLU D 1 23  ? 62.590  -48.602 126.895 1.00 51.90  ? 42  GLU D C   1 
ATOM   8514  O O   . GLU D 1 23  ? 62.457  -47.784 127.810 1.00 52.16  ? 42  GLU D O   1 
ATOM   8515  C CB  . GLU D 1 23  ? 64.803  -47.924 125.955 1.00 54.42  ? 42  GLU D CB  1 
ATOM   8516  N N   . PHE D 1 24  ? 62.078  -49.830 126.906 1.00 49.44  ? 43  PHE D N   1 
ATOM   8517  C CA  . PHE D 1 24  ? 61.221  -50.347 127.963 1.00 48.24  ? 43  PHE D CA  1 
ATOM   8518  C C   . PHE D 1 24  ? 61.948  -51.368 128.825 1.00 48.50  ? 43  PHE D C   1 
ATOM   8519  O O   . PHE D 1 24  ? 62.748  -52.157 128.316 1.00 49.33  ? 43  PHE D O   1 
ATOM   8520  C CB  . PHE D 1 24  ? 59.988  -51.004 127.376 1.00 47.18  ? 43  PHE D CB  1 
ATOM   8521  C CG  . PHE D 1 24  ? 59.102  -51.598 128.396 1.00 45.90  ? 43  PHE D CG  1 
ATOM   8522  C CD1 . PHE D 1 24  ? 58.094  -50.853 128.936 1.00 45.66  ? 43  PHE D CD1 1 
ATOM   8523  C CD2 . PHE D 1 24  ? 59.276  -52.887 128.837 1.00 45.83  ? 43  PHE D CD2 1 
ATOM   8524  C CE1 . PHE D 1 24  ? 57.249  -51.376 129.872 1.00 44.93  ? 43  PHE D CE1 1 
ATOM   8525  C CE2 . PHE D 1 24  ? 58.438  -53.410 129.788 1.00 44.82  ? 43  PHE D CE2 1 
ATOM   8526  C CZ  . PHE D 1 24  ? 57.419  -52.643 130.302 1.00 44.40  ? 43  PHE D CZ  1 
ATOM   8527  N N   . SER D 1 25  ? 61.622  -51.362 130.122 1.00 47.03  ? 44  SER D N   1 
ATOM   8528  C CA  . SER D 1 25  ? 62.257  -52.205 131.118 1.00 47.23  ? 44  SER D CA  1 
ATOM   8529  C C   . SER D 1 25  ? 61.238  -52.588 132.187 1.00 45.82  ? 44  SER D C   1 
ATOM   8530  O O   . SER D 1 25  ? 60.345  -51.811 132.534 1.00 45.18  ? 44  SER D O   1 
ATOM   8531  C CB  . SER D 1 25  ? 63.460  -51.529 131.804 1.00 48.71  ? 44  SER D CB  1 
ATOM   8532  O OG  . SER D 1 25  ? 64.015  -52.368 132.811 1.00 48.81  ? 44  SER D OG  1 
ATOM   8533  N N   . TRP D 1 26  ? 61.418  -53.798 132.728 1.00 49.34  ? 45  TRP D N   1 
ATOM   8534  C CA  . TRP D 1 26  ? 60.662  -54.302 133.855 1.00 48.24  ? 45  TRP D CA  1 
ATOM   8535  C C   . TRP D 1 26  ? 61.399  -54.131 135.184 1.00 47.77  ? 45  TRP D C   1 
ATOM   8536  O O   . TRP D 1 26  ? 60.865  -54.520 136.231 1.00 46.98  ? 45  TRP D O   1 
ATOM   8537  C CB  . TRP D 1 26  ? 60.366  -55.784 133.626 1.00 48.18  ? 45  TRP D CB  1 
ATOM   8538  C CG  . TRP D 1 26  ? 59.285  -56.109 132.659 1.00 47.35  ? 45  TRP D CG  1 
ATOM   8539  C CD1 . TRP D 1 26  ? 59.426  -56.764 131.494 1.00 47.73  ? 45  TRP D CD1 1 
ATOM   8540  C CD2 . TRP D 1 26  ? 57.893  -55.822 132.798 1.00 45.92  ? 45  TRP D CD2 1 
ATOM   8541  N NE1 . TRP D 1 26  ? 58.213  -56.897 130.883 1.00 46.58  ? 45  TRP D NE1 1 
ATOM   8542  C CE2 . TRP D 1 26  ? 57.253  -56.329 131.671 1.00 45.66  ? 45  TRP D CE2 1 
ATOM   8543  C CE3 . TRP D 1 26  ? 57.131  -55.170 133.763 1.00 45.12  ? 45  TRP D CE3 1 
ATOM   8544  C CZ2 . TRP D 1 26  ? 55.883  -56.225 131.477 1.00 44.49  ? 45  TRP D CZ2 1 
ATOM   8545  C CZ3 . TRP D 1 26  ? 55.768  -55.057 133.564 1.00 44.13  ? 45  TRP D CZ3 1 
ATOM   8546  C CH2 . TRP D 1 26  ? 55.161  -55.596 132.438 1.00 44.08  ? 45  TRP D CH2 1 
ATOM   8547  N N   . ASP D 1 27  ? 62.616  -53.588 135.176 1.00 49.98  ? 46  ASP D N   1 
ATOM   8548  C CA  . ASP D 1 27  ? 63.384  -53.537 136.422 1.00 49.77  ? 46  ASP D CA  1 
ATOM   8549  C C   . ASP D 1 27  ? 62.581  -52.900 137.560 1.00 48.12  ? 46  ASP D C   1 
ATOM   8550  O O   . ASP D 1 27  ? 62.614  -53.384 138.701 1.00 47.40  ? 46  ASP D O   1 
ATOM   8551  C CB  . ASP D 1 27  ? 64.707  -52.795 136.203 1.00 51.03  ? 46  ASP D CB  1 
ATOM   8552  C CG  . ASP D 1 27  ? 65.624  -53.517 135.223 1.00 53.02  ? 46  ASP D CG  1 
ATOM   8553  O OD1 . ASP D 1 27  ? 65.369  -54.700 134.957 1.00 54.03  ? 46  ASP D OD1 1 
ATOM   8554  O OD2 . ASP D 1 27  ? 66.590  -52.906 134.710 1.00 54.57  ? 46  ASP D OD2 1 
ATOM   8555  N N   . THR D 1 28  ? 61.854  -51.820 137.269 1.00 48.74  ? 47  THR D N   1 
ATOM   8556  C CA  . THR D 1 28  ? 60.906  -51.233 138.200 1.00 46.66  ? 47  THR D CA  1 
ATOM   8557  C C   . THR D 1 28  ? 59.635  -50.871 137.426 1.00 45.87  ? 47  THR D C   1 
ATOM   8558  O O   . THR D 1 28  ? 59.601  -50.910 136.193 1.00 47.23  ? 47  THR D O   1 
ATOM   8559  C CB  . THR D 1 28  ? 61.457  -49.975 138.892 1.00 46.54  ? 47  THR D CB  1 
ATOM   8560  O OG1 . THR D 1 28  ? 61.845  -49.004 137.902 1.00 48.07  ? 47  THR D OG1 1 
ATOM   8561  C CG2 . THR D 1 28  ? 62.640  -50.266 139.758 1.00 47.31  ? 47  THR D CG2 1 
ATOM   8562  N N   . VAL D 1 29  ? 58.597  -50.492 138.164 1.00 44.22  ? 48  VAL D N   1 
ATOM   8563  C CA  . VAL D 1 29  ? 57.329  -50.071 137.591 1.00 43.24  ? 48  VAL D CA  1 
ATOM   8564  C C   . VAL D 1 29  ? 57.591  -49.131 136.416 1.00 44.81  ? 48  VAL D C   1 
ATOM   8565  O O   . VAL D 1 29  ? 58.302  -48.125 136.567 1.00 45.45  ? 48  VAL D O   1 
ATOM   8566  C CB  . VAL D 1 29  ? 56.456  -49.377 138.645 1.00 40.89  ? 48  VAL D CB  1 
ATOM   8567  C CG1 . VAL D 1 29  ? 55.230  -48.751 137.962 1.00 40.28  ? 48  VAL D CG1 1 
ATOM   8568  C CG2 . VAL D 1 29  ? 56.057  -50.325 139.745 1.00 39.37  ? 48  VAL D CG2 1 
ATOM   8569  N N   . PRO D 1 30  ? 57.063  -49.425 135.224 1.00 41.73  ? 49  PRO D N   1 
ATOM   8570  C CA  . PRO D 1 30  ? 57.307  -48.547 134.065 1.00 43.45  ? 49  PRO D CA  1 
ATOM   8571  C C   . PRO D 1 30  ? 56.451  -47.295 134.133 1.00 42.67  ? 49  PRO D C   1 
ATOM   8572  O O   . PRO D 1 30  ? 55.224  -47.368 134.125 1.00 41.39  ? 49  PRO D O   1 
ATOM   8573  C CB  . PRO D 1 30  ? 56.933  -49.423 132.866 1.00 45.16  ? 49  PRO D CB  1 
ATOM   8574  C CG  . PRO D 1 30  ? 56.054  -50.477 133.408 1.00 44.49  ? 49  PRO D CG  1 
ATOM   8575  C CD  . PRO D 1 30  ? 56.356  -50.665 134.863 1.00 42.13  ? 49  PRO D CD  1 
ATOM   8576  N N   . ILE D 1 31  ? 57.114  -46.140 134.192 1.00 44.91  ? 50  ILE D N   1 
ATOM   8577  C CA  . ILE D 1 31  ? 56.514  -44.849 134.500 1.00 44.17  ? 50  ILE D CA  1 
ATOM   8578  C C   . ILE D 1 31  ? 56.637  -43.977 133.266 1.00 45.80  ? 50  ILE D C   1 
ATOM   8579  O O   . ILE D 1 31  ? 57.677  -43.989 132.591 1.00 48.00  ? 50  ILE D O   1 
ATOM   8580  C CB  . ILE D 1 31  ? 57.241  -44.186 135.685 1.00 43.88  ? 50  ILE D CB  1 
ATOM   8581  C CG1 . ILE D 1 31  ? 57.060  -45.008 136.954 1.00 42.27  ? 50  ILE D CG1 1 
ATOM   8582  C CG2 . ILE D 1 31  ? 56.762  -42.730 135.883 1.00 43.42  ? 50  ILE D CG2 1 
ATOM   8583  C CD1 . ILE D 1 31  ? 55.621  -45.150 137.390 1.00 39.74  ? 50  ILE D CD1 1 
ATOM   8584  N N   . ALA D 1 32  ? 55.594  -43.211 132.975 1.00 45.27  ? 51  ALA D N   1 
ATOM   8585  C CA  . ALA D 1 32  ? 55.667  -42.116 132.004 1.00 47.10  ? 51  ALA D CA  1 
ATOM   8586  C C   . ALA D 1 32  ? 55.232  -40.810 132.664 1.00 45.47  ? 51  ALA D C   1 
ATOM   8587  O O   . ALA D 1 32  ? 54.681  -40.800 133.767 1.00 43.03  ? 51  ALA D O   1 
ATOM   8588  C CB  . ALA D 1 32  ? 54.808  -42.423 130.769 1.00 48.34  ? 51  ALA D CB  1 
ATOM   8589  N N   . PHE D 1 33  ? 55.490  -39.692 131.990 1.00 48.90  ? 52  PHE D N   1 
ATOM   8590  C CA  . PHE D 1 33  ? 55.075  -38.394 132.506 1.00 47.59  ? 52  PHE D CA  1 
ATOM   8591  C C   . PHE D 1 33  ? 54.251  -37.656 131.463 1.00 48.59  ? 52  PHE D C   1 
ATOM   8592  O O   . PHE D 1 33  ? 54.546  -37.723 130.265 1.00 50.96  ? 52  PHE D O   1 
ATOM   8593  C CB  . PHE D 1 33  ? 56.267  -37.524 132.914 1.00 48.84  ? 52  PHE D CB  1 
ATOM   8594  C CG  . PHE D 1 33  ? 57.033  -38.026 134.128 1.00 47.87  ? 52  PHE D CG  1 
ATOM   8595  C CD1 . PHE D 1 33  ? 56.577  -37.778 135.417 1.00 45.55  ? 52  PHE D CD1 1 
ATOM   8596  C CD2 . PHE D 1 33  ? 58.240  -38.715 133.976 1.00 49.31  ? 52  PHE D CD2 1 
ATOM   8597  C CE1 . PHE D 1 33  ? 57.313  -38.214 136.529 1.00 45.18  ? 52  PHE D CE1 1 
ATOM   8598  C CE2 . PHE D 1 33  ? 58.975  -39.154 135.076 1.00 48.77  ? 52  PHE D CE2 1 
ATOM   8599  C CZ  . PHE D 1 33  ? 58.517  -38.902 136.351 1.00 46.87  ? 52  PHE D CZ  1 
ATOM   8600  N N   . HIS D 1 34  ? 53.238  -36.932 131.940 1.00 48.16  ? 53  HIS D N   1 
ATOM   8601  C CA  . HIS D 1 34  ? 52.353  -36.166 131.070 1.00 49.03  ? 53  HIS D CA  1 
ATOM   8602  C C   . HIS D 1 34  ? 51.940  -34.900 131.811 1.00 47.43  ? 53  HIS D C   1 
ATOM   8603  O O   . HIS D 1 34  ? 50.967  -34.919 132.573 1.00 45.05  ? 53  HIS D O   1 
ATOM   8604  C CB  . HIS D 1 34  ? 51.134  -36.977 130.670 1.00 48.25  ? 53  HIS D CB  1 
ATOM   8605  C CG  . HIS D 1 34  ? 50.245  -36.276 129.698 1.00 49.57  ? 53  HIS D CG  1 
ATOM   8606  N ND1 . HIS D 1 34  ? 49.858  -36.845 128.509 1.00 52.48  ? 53  HIS D ND1 1 
ATOM   8607  C CD2 . HIS D 1 34  ? 49.676  -35.051 129.727 1.00 49.47  ? 53  HIS D CD2 1 
ATOM   8608  C CE1 . HIS D 1 34  ? 49.076  -36.010 127.849 1.00 52.80  ? 53  HIS D CE1 1 
ATOM   8609  N NE2 . HIS D 1 34  ? 48.948  -34.912 128.568 1.00 51.15  ? 53  HIS D NE2 1 
ATOM   8610  N N   . PHE D 1 35  ? 52.665  -33.809 131.569 1.00 48.95  ? 54  PHE D N   1 
ATOM   8611  C CA  . PHE D 1 35  ? 52.377  -32.588 132.300 1.00 47.94  ? 54  PHE D CA  1 
ATOM   8612  C C   . PHE D 1 35  ? 52.983  -31.394 131.589 1.00 50.10  ? 54  PHE D C   1 
ATOM   8613  O O   . PHE D 1 35  ? 53.867  -31.533 130.740 1.00 52.14  ? 54  PHE D O   1 
ATOM   8614  C CB  . PHE D 1 35  ? 52.911  -32.686 133.738 1.00 46.21  ? 54  PHE D CB  1 
ATOM   8615  C CG  . PHE D 1 35  ? 54.417  -32.685 133.823 1.00 47.73  ? 54  PHE D CG  1 
ATOM   8616  C CD1 . PHE D 1 35  ? 55.126  -31.507 133.741 1.00 49.70  ? 54  PHE D CD1 1 
ATOM   8617  C CD2 . PHE D 1 35  ? 55.116  -33.868 133.970 1.00 47.87  ? 54  PHE D CD2 1 
ATOM   8618  C CE1 . PHE D 1 35  ? 56.491  -31.527 133.795 1.00 51.37  ? 54  PHE D CE1 1 
ATOM   8619  C CE2 . PHE D 1 35  ? 56.481  -33.878 134.035 1.00 49.40  ? 54  PHE D CE2 1 
ATOM   8620  C CZ  . PHE D 1 35  ? 57.172  -32.714 133.946 1.00 51.17  ? 54  PHE D CZ  1 
ATOM   8621  N N   . GLY D 1 36  ? 52.506  -30.232 131.969 1.00 52.58  ? 55  GLY D N   1 
ATOM   8622  C CA  . GLY D 1 36  ? 53.132  -28.976 131.562 1.00 54.37  ? 55  GLY D CA  1 
ATOM   8623  C C   . GLY D 1 36  ? 53.409  -28.043 132.719 1.00 53.47  ? 55  GLY D C   1 
ATOM   8624  O O   . GLY D 1 36  ? 52.617  -27.967 133.659 1.00 51.78  ? 55  GLY D O   1 
ATOM   8625  N N   . LYS D 1 37  ? 54.516  -27.338 132.645 1.00 54.65  ? 56  LYS D N   1 
ATOM   8626  C CA  . LYS D 1 37  ? 54.888  -26.325 133.642 1.00 54.37  ? 56  LYS D CA  1 
ATOM   8627  C C   . LYS D 1 37  ? 54.825  -24.965 132.946 1.00 56.15  ? 56  LYS D C   1 
ATOM   8628  O O   . LYS D 1 37  ? 55.738  -24.599 132.207 1.00 58.10  ? 56  LYS D O   1 
ATOM   8629  C CB  . LYS D 1 37  ? 56.279  -26.594 134.216 1.00 54.94  ? 56  LYS D CB  1 
ATOM   8630  C CG  . LYS D 1 37  ? 56.813  -25.504 135.159 1.00 55.70  ? 56  LYS D CG  1 
ATOM   8631  C CD  . LYS D 1 37  ? 58.296  -25.740 135.488 1.00 57.75  ? 56  LYS D CD  1 
ATOM   8632  C CE  . LYS D 1 37  ? 58.880  -24.622 136.335 1.00 60.69  ? 56  LYS D CE  1 
ATOM   8633  N NZ  . LYS D 1 37  ? 60.320  -24.818 136.657 1.00 62.89  ? 56  LYS D NZ  1 
ATOM   8634  N N   . SER D 1 38  ? 53.740  -24.224 133.188 1.00 54.84  ? 57  SER D N   1 
ATOM   8635  C CA  . SER D 1 38  ? 53.536  -22.956 132.480 1.00 56.69  ? 57  SER D CA  1 
ATOM   8636  C C   . SER D 1 38  ? 54.571  -21.910 132.908 1.00 58.28  ? 57  SER D C   1 
ATOM   8637  O O   . SER D 1 38  ? 55.101  -21.181 132.064 1.00 60.07  ? 57  SER D O   1 
ATOM   8638  C CB  . SER D 1 38  ? 52.099  -22.461 132.695 1.00 55.96  ? 57  SER D CB  1 
ATOM   8639  N N   . GLN D 1 39  ? 54.919  -21.861 134.214 1.00 57.69  ? 58  GLN D N   1 
ATOM   8640  C CA  . GLN D 1 39  ? 55.704  -20.746 134.759 1.00 60.91  ? 58  GLN D CA  1 
ATOM   8641  C C   . GLN D 1 39  ? 57.114  -20.694 134.194 1.00 62.85  ? 58  GLN D C   1 
ATOM   8642  O O   . GLN D 1 39  ? 57.809  -19.702 134.398 1.00 65.82  ? 58  GLN D O   1 
ATOM   8643  C CB  . GLN D 1 39  ? 55.772  -20.803 136.290 1.00 61.52  ? 58  GLN D CB  1 
ATOM   8644  N N   . GLY D 1 40  ? 57.539  -21.705 133.462 1.00 61.50  ? 59  GLY D N   1 
ATOM   8645  C CA  . GLY D 1 40  ? 58.850  -21.691 132.861 1.00 63.48  ? 59  GLY D CA  1 
ATOM   8646  C C   . GLY D 1 40  ? 59.287  -23.115 132.564 1.00 61.67  ? 59  GLY D C   1 
ATOM   8647  O O   . GLY D 1 40  ? 58.514  -24.052 132.678 1.00 58.73  ? 59  GLY D O   1 
ATOM   8648  N N   . LEU D 1 41  ? 60.533  -23.236 132.156 1.00 65.05  ? 60  LEU D N   1 
ATOM   8649  C CA  . LEU D 1 41  ? 61.088  -24.544 131.929 1.00 63.87  ? 60  LEU D CA  1 
ATOM   8650  C C   . LEU D 1 41  ? 61.347  -25.233 133.259 1.00 63.24  ? 60  LEU D C   1 
ATOM   8651  O O   . LEU D 1 41  ? 61.473  -24.602 134.317 1.00 64.70  ? 60  LEU D O   1 
ATOM   8652  C CB  . LEU D 1 41  ? 62.404  -24.464 131.167 1.00 66.42  ? 60  LEU D CB  1 
ATOM   8653  C CG  . LEU D 1 41  ? 62.328  -24.014 129.711 1.00 67.55  ? 60  LEU D CG  1 
ATOM   8654  C CD1 . LEU D 1 41  ? 63.732  -23.790 129.159 1.00 70.82  ? 60  LEU D CD1 1 
ATOM   8655  C CD2 . LEU D 1 41  ? 61.558  -25.039 128.860 1.00 66.15  ? 60  LEU D CD2 1 
ATOM   8656  N N   . LEU D 1 42  ? 61.456  -26.549 133.187 1.00 64.21  ? 61  LEU D N   1 
ATOM   8657  C CA  . LEU D 1 42  ? 61.839  -27.321 134.353 1.00 63.99  ? 61  LEU D CA  1 
ATOM   8658  C C   . LEU D 1 42  ? 63.205  -26.892 134.866 1.00 67.46  ? 61  LEU D C   1 
ATOM   8659  O O   . LEU D 1 42  ? 64.127  -26.651 134.083 1.00 69.47  ? 61  LEU D O   1 
ATOM   8660  C CB  . LEU D 1 42  ? 61.885  -28.792 133.982 1.00 62.98  ? 61  LEU D CB  1 
ATOM   8661  C CG  . LEU D 1 42  ? 60.616  -29.525 133.579 1.00 62.21  ? 61  LEU D CG  1 
ATOM   8662  C CD1 . LEU D 1 42  ? 61.084  -30.883 133.050 1.00 62.31  ? 61  LEU D CD1 1 
ATOM   8663  C CD2 . LEU D 1 42  ? 59.746  -29.619 134.782 1.00 60.79  ? 61  LEU D CD2 1 
ATOM   8664  N N   . THR D 1 43  ? 63.342  -26.837 136.191 1.00 64.76  ? 62  THR D N   1 
ATOM   8665  C CA  . THR D 1 43  ? 64.618  -26.463 136.794 1.00 67.91  ? 62  THR D CA  1 
ATOM   8666  C C   . THR D 1 43  ? 65.609  -27.615 136.640 1.00 68.16  ? 62  THR D C   1 
ATOM   8667  O O   . THR D 1 43  ? 65.261  -28.720 136.200 1.00 65.68  ? 62  THR D O   1 
ATOM   8668  C CB  . THR D 1 43  ? 64.454  -26.102 138.271 1.00 69.39  ? 62  THR D CB  1 
ATOM   8669  O OG1 . THR D 1 43  ? 64.392  -27.299 139.054 1.00 72.36  ? 62  THR D OG1 1 
ATOM   8670  C CG2 . THR D 1 43  ? 63.192  -25.312 138.523 1.00 66.71  ? 62  THR D CG2 1 
ATOM   8671  N N   . LYS D 1 44  ? 66.867  -27.344 136.994 1.00 69.97  ? 63  LYS D N   1 
ATOM   8672  C CA  . LYS D 1 44  ? 67.873  -28.397 136.959 1.00 70.72  ? 63  LYS D CA  1 
ATOM   8673  C C   . LYS D 1 44  ? 67.426  -29.587 137.805 1.00 68.36  ? 63  LYS D C   1 
ATOM   8674  O O   . LYS D 1 44  ? 67.420  -30.728 137.335 1.00 66.74  ? 63  LYS D O   1 
ATOM   8675  C CB  . LYS D 1 44  ? 69.223  -27.845 137.431 1.00 75.32  ? 63  LYS D CB  1 
ATOM   8676  N N   . GLU D 1 45  ? 67.020  -29.335 139.054 1.00 70.54  ? 64  GLU D N   1 
ATOM   8677  C CA  . GLU D 1 45  ? 66.644  -30.431 139.937 1.00 69.11  ? 64  GLU D CA  1 
ATOM   8678  C C   . GLU D 1 45  ? 65.471  -31.209 139.356 1.00 64.45  ? 64  GLU D C   1 
ATOM   8679  O O   . GLU D 1 45  ? 65.458  -32.450 139.393 1.00 62.96  ? 64  GLU D O   1 
ATOM   8680  C CB  . GLU D 1 45  ? 66.304  -29.904 141.330 1.00 70.99  ? 64  GLU D CB  1 
ATOM   8681  N N   . GLU D 1 46  ? 64.490  -30.495 138.772 1.00 68.02  ? 65  GLU D N   1 
ATOM   8682  C CA  . GLU D 1 46  ? 63.266  -31.144 138.287 1.00 64.60  ? 65  GLU D CA  1 
ATOM   8683  C C   . GLU D 1 46  ? 63.518  -31.976 137.032 1.00 63.87  ? 65  GLU D C   1 
ATOM   8684  O O   . GLU D 1 46  ? 62.873  -33.006 136.839 1.00 62.21  ? 65  GLU D O   1 
ATOM   8685  C CB  . GLU D 1 46  ? 62.174  -30.099 138.010 1.00 63.74  ? 65  GLU D CB  1 
ATOM   8686  C CG  . GLU D 1 46  ? 61.464  -29.530 139.263 1.00 64.53  ? 65  GLU D CG  1 
ATOM   8687  C CD  . GLU D 1 46  ? 60.797  -28.139 139.025 1.00 65.40  ? 65  GLU D CD  1 
ATOM   8688  O OE1 . GLU D 1 46  ? 60.989  -27.527 137.946 1.00 65.37  ? 65  GLU D OE1 1 
ATOM   8689  O OE2 . GLU D 1 46  ? 60.078  -27.654 139.933 1.00 66.38  ? 65  GLU D OE2 1 
ATOM   8690  N N   . ALA D 1 47  ? 64.459  -31.561 136.185 1.00 63.34  ? 66  ALA D N   1 
ATOM   8691  C CA  . ALA D 1 47  ? 64.758  -32.317 134.976 1.00 63.52  ? 66  ALA D CA  1 
ATOM   8692  C C   . ALA D 1 47  ? 65.651  -33.519 135.256 1.00 63.85  ? 66  ALA D C   1 
ATOM   8693  O O   . ALA D 1 47  ? 65.428  -34.588 134.671 1.00 63.70  ? 66  ALA D O   1 
ATOM   8694  C CB  . ALA D 1 47  ? 65.406  -31.409 133.934 1.00 65.74  ? 66  ALA D CB  1 
ATOM   8695  N N   . GLU D 1 48  ? 66.663  -33.387 136.130 1.00 63.42  ? 67  GLU D N   1 
ATOM   8696  C CA  . GLU D 1 48  ? 67.353  -34.583 136.619 1.00 63.76  ? 67  GLU D CA  1 
ATOM   8697  C C   . GLU D 1 48  ? 66.320  -35.604 137.086 1.00 60.72  ? 67  GLU D C   1 
ATOM   8698  O O   . GLU D 1 48  ? 66.321  -36.774 136.664 1.00 60.82  ? 67  GLU D O   1 
ATOM   8699  C CB  . GLU D 1 48  ? 68.318  -34.244 137.757 1.00 66.77  ? 67  GLU D CB  1 
ATOM   8700  N N   . PHE D 1 49  ? 65.375  -35.143 137.908 1.00 61.36  ? 68  PHE D N   1 
ATOM   8701  C CA  . PHE D 1 49  ? 64.317  -36.014 138.405 1.00 58.72  ? 68  PHE D CA  1 
ATOM   8702  C C   . PHE D 1 49  ? 63.597  -36.730 137.269 1.00 58.60  ? 68  PHE D C   1 
ATOM   8703  O O   . PHE D 1 49  ? 63.464  -37.949 137.263 1.00 58.60  ? 68  PHE D O   1 
ATOM   8704  C CB  . PHE D 1 49  ? 63.340  -35.183 139.236 1.00 58.23  ? 68  PHE D CB  1 
ATOM   8705  C CG  . PHE D 1 49  ? 62.235  -35.981 139.821 1.00 55.63  ? 68  PHE D CG  1 
ATOM   8706  C CD1 . PHE D 1 49  ? 61.088  -36.207 139.113 1.00 54.23  ? 68  PHE D CD1 1 
ATOM   8707  C CD2 . PHE D 1 49  ? 62.343  -36.507 141.081 1.00 56.14  ? 68  PHE D CD2 1 
ATOM   8708  C CE1 . PHE D 1 49  ? 60.071  -36.956 139.664 1.00 52.43  ? 68  PHE D CE1 1 
ATOM   8709  C CE2 . PHE D 1 49  ? 61.332  -37.246 141.617 1.00 54.30  ? 68  PHE D CE2 1 
ATOM   8710  C CZ  . PHE D 1 49  ? 60.198  -37.472 140.917 1.00 51.58  ? 68  PHE D CZ  1 
ATOM   8711  N N   . VAL D 1 50  ? 63.115  -35.986 136.294 1.00 57.55  ? 69  VAL D N   1 
ATOM   8712  C CA  . VAL D 1 50  ? 62.269  -36.617 135.285 1.00 57.95  ? 69  VAL D CA  1 
ATOM   8713  C C   . VAL D 1 50  ? 63.113  -37.487 134.365 1.00 59.46  ? 69  VAL D C   1 
ATOM   8714  O O   . VAL D 1 50  ? 62.744  -38.619 134.060 1.00 59.16  ? 69  VAL D O   1 
ATOM   8715  C CB  . VAL D 1 50  ? 61.475  -35.535 134.530 1.00 59.30  ? 69  VAL D CB  1 
ATOM   8716  C CG1 . VAL D 1 50  ? 60.993  -36.027 133.221 1.00 61.03  ? 69  VAL D CG1 1 
ATOM   8717  C CG2 . VAL D 1 50  ? 60.302  -35.121 135.377 1.00 57.31  ? 69  VAL D CG2 1 
ATOM   8718  N N   . ALA D 1 51  ? 64.275  -36.995 133.944 1.00 60.07  ? 70  ALA D N   1 
ATOM   8719  C CA  . ALA D 1 51  ? 65.036  -37.712 132.935 1.00 61.39  ? 70  ALA D CA  1 
ATOM   8720  C C   . ALA D 1 51  ? 65.599  -39.002 133.479 1.00 61.09  ? 70  ALA D C   1 
ATOM   8721  O O   . ALA D 1 51  ? 65.932  -39.895 132.694 1.00 61.89  ? 70  ALA D O   1 
ATOM   8722  C CB  . ALA D 1 51  ? 66.170  -36.843 132.400 1.00 63.63  ? 70  ALA D CB  1 
ATOM   8723  N N   . THR D 1 52  ? 65.688  -39.128 134.804 1.00 61.09  ? 71  THR D N   1 
ATOM   8724  C CA  . THR D 1 52  ? 66.247  -40.323 135.427 1.00 61.18  ? 71  THR D CA  1 
ATOM   8725  C C   . THR D 1 52  ? 65.206  -41.398 135.731 1.00 59.67  ? 71  THR D C   1 
ATOM   8726  O O   . THR D 1 52  ? 65.594  -42.522 136.062 1.00 60.75  ? 71  THR D O   1 
ATOM   8727  C CB  . THR D 1 52  ? 67.012  -39.942 136.720 1.00 61.57  ? 71  THR D CB  1 
ATOM   8728  O OG1 . THR D 1 52  ? 67.601  -41.120 137.287 1.00 62.24  ? 71  THR D OG1 1 
ATOM   8729  C CG2 . THR D 1 52  ? 66.118  -39.320 137.787 1.00 60.41  ? 71  THR D CG2 1 
ATOM   8730  N N   . ARG D 1 53  ? 63.914  -41.098 135.616 1.00 58.57  ? 72  ARG D N   1 
ATOM   8731  C CA  . ARG D 1 53  ? 62.874  -42.020 136.042 1.00 56.93  ? 72  ARG D CA  1 
ATOM   8732  C C   . ARG D 1 53  ? 61.949  -42.413 134.919 1.00 57.09  ? 72  ARG D C   1 
ATOM   8733  O O   . ARG D 1 53  ? 60.972  -43.135 135.168 1.00 56.06  ? 72  ARG D O   1 
ATOM   8734  C CB  . ARG D 1 53  ? 62.043  -41.434 137.185 1.00 55.06  ? 72  ARG D CB  1 
ATOM   8735  C CG  . ARG D 1 53  ? 62.962  -40.761 138.060 1.00 55.14  ? 72  ARG D CG  1 
ATOM   8736  C CD  . ARG D 1 53  ? 62.518  -40.372 139.414 1.00 53.58  ? 72  ARG D CD  1 
ATOM   8737  N NE  . ARG D 1 53  ? 63.628  -39.535 139.855 1.00 54.78  ? 72  ARG D NE  1 
ATOM   8738  C CZ  . ARG D 1 53  ? 64.090  -39.467 141.086 1.00 55.84  ? 72  ARG D CZ  1 
ATOM   8739  N NH1 . ARG D 1 53  ? 63.445  -40.027 142.091 1.00 55.26  ? 72  ARG D NH1 1 
ATOM   8740  N NH2 . ARG D 1 53  ? 65.223  -38.802 141.316 1.00 59.07  ? 72  ARG D NH2 1 
ATOM   8741  N N   . SER D 1 54  ? 62.216  -41.960 133.698 1.00 53.73  ? 73  SER D N   1 
ATOM   8742  C CA  . SER D 1 54  ? 61.391  -42.355 132.569 1.00 54.21  ? 73  SER D CA  1 
ATOM   8743  C C   . SER D 1 54  ? 62.134  -42.087 131.274 1.00 56.15  ? 73  SER D C   1 
ATOM   8744  O O   . SER D 1 54  ? 63.047  -41.252 131.202 1.00 57.44  ? 73  SER D O   1 
ATOM   8745  C CB  . SER D 1 54  ? 60.057  -41.616 132.566 1.00 53.42  ? 73  SER D CB  1 
ATOM   8746  O OG  . SER D 1 54  ? 59.337  -41.943 131.396 1.00 54.27  ? 73  SER D OG  1 
ATOM   8747  N N   . ASN D 1 55  ? 61.710  -42.822 130.242 1.00 54.55  ? 74  ASN D N   1 
ATOM   8748  C CA  . ASN D 1 55  ? 62.125  -42.571 128.871 1.00 55.74  ? 74  ASN D CA  1 
ATOM   8749  C C   . ASN D 1 55  ? 60.970  -42.059 128.024 1.00 55.85  ? 74  ASN D C   1 
ATOM   8750  O O   . ASN D 1 55  ? 61.089  -42.001 126.796 1.00 56.90  ? 74  ASN D O   1 
ATOM   8751  C CB  . ASN D 1 55  ? 62.714  -43.830 128.229 1.00 56.24  ? 74  ASN D CB  1 
ATOM   8752  C CG  . ASN D 1 55  ? 64.079  -44.203 128.792 1.00 56.89  ? 74  ASN D CG  1 
ATOM   8753  O OD1 . ASN D 1 55  ? 64.804  -43.366 129.342 1.00 58.07  ? 74  ASN D OD1 1 
ATOM   8754  N ND2 . ASN D 1 55  ? 64.431  -45.477 128.659 1.00 57.54  ? 74  ASN D ND2 1 
ATOM   8755  N N   . PHE D 1 56  ? 59.868  -41.657 128.654 1.00 51.59  ? 75  PHE D N   1 
ATOM   8756  C CA  . PHE D 1 56  ? 58.625  -41.380 127.941 1.00 51.26  ? 75  PHE D CA  1 
ATOM   8757  C C   . PHE D 1 56  ? 57.904  -40.242 128.648 1.00 50.65  ? 75  PHE D C   1 
ATOM   8758  O O   . PHE D 1 56  ? 57.389  -40.439 129.754 1.00 49.52  ? 75  PHE D O   1 
ATOM   8759  C CB  . PHE D 1 56  ? 57.782  -42.646 127.898 1.00 51.07  ? 75  PHE D CB  1 
ATOM   8760  C CG  . PHE D 1 56  ? 56.776  -42.695 126.792 1.00 51.27  ? 75  PHE D CG  1 
ATOM   8761  C CD1 . PHE D 1 56  ? 56.853  -41.866 125.683 1.00 52.09  ? 75  PHE D CD1 1 
ATOM   8762  C CD2 . PHE D 1 56  ? 55.738  -43.601 126.867 1.00 50.79  ? 75  PHE D CD2 1 
ATOM   8763  C CE1 . PHE D 1 56  ? 55.917  -41.948 124.686 1.00 51.89  ? 75  PHE D CE1 1 
ATOM   8764  C CE2 . PHE D 1 56  ? 54.798  -43.670 125.879 1.00 50.61  ? 75  PHE D CE2 1 
ATOM   8765  C CZ  . PHE D 1 56  ? 54.886  -42.843 124.790 1.00 50.95  ? 75  PHE D CZ  1 
ATOM   8766  N N   . ILE D 1 57  ? 57.922  -39.051 128.042 1.00 52.53  ? 76  ILE D N   1 
ATOM   8767  C CA  . ILE D 1 57  ? 57.268  -37.844 128.628 1.00 51.70  ? 76  ILE D CA  1 
ATOM   8768  C C   . ILE D 1 57  ? 56.460  -37.146 127.527 1.00 52.47  ? 76  ILE D C   1 
ATOM   8769  O O   . ILE D 1 57  ? 56.866  -37.270 126.358 1.00 53.84  ? 76  ILE D O   1 
ATOM   8770  C CB  . ILE D 1 57  ? 58.302  -36.894 129.260 1.00 51.78  ? 76  ILE D CB  1 
ATOM   8771  C CG1 . ILE D 1 57  ? 57.621  -35.675 129.881 1.00 50.98  ? 76  ILE D CG1 1 
ATOM   8772  C CG2 . ILE D 1 57  ? 59.378  -36.486 128.252 1.00 53.59  ? 76  ILE D CG2 1 
ATOM   8773  C CD1 . ILE D 1 57  ? 58.405  -35.030 131.007 1.00 50.72  ? 76  ILE D CD1 1 
ATOM   8774  N N   . CYS D 1 58  ? 55.357  -36.482 127.875 1.00 53.92  ? 77  CYS D N   1 
ATOM   8775  C CA  . CYS D 1 58  ? 54.536  -35.703 126.913 1.00 54.17  ? 77  CYS D CA  1 
ATOM   8776  C C   . CYS D 1 58  ? 54.305  -34.304 127.499 1.00 53.83  ? 77  CYS D C   1 
ATOM   8777  O O   . CYS D 1 58  ? 53.613  -34.207 128.531 1.00 51.99  ? 77  CYS D O   1 
ATOM   8778  C CB  . CYS D 1 58  ? 53.196  -36.369 126.636 1.00 53.61  ? 77  CYS D CB  1 
ATOM   8779  S SG  . CYS D 1 58  ? 52.051  -35.305 125.719 1.00 53.72  ? 77  CYS D SG  1 
ATOM   8780  N N   . LEU D 1 59  ? 54.857  -33.273 126.860 1.00 54.41  ? 78  LEU D N   1 
ATOM   8781  C CA  . LEU D 1 59  ? 54.741  -31.896 127.404 1.00 53.89  ? 78  LEU D CA  1 
ATOM   8782  C C   . LEU D 1 59  ? 53.378  -31.310 127.011 1.00 53.52  ? 78  LEU D C   1 
ATOM   8783  O O   . LEU D 1 59  ? 53.117  -31.231 125.796 1.00 54.63  ? 78  LEU D O   1 
ATOM   8784  C CB  . LEU D 1 59  ? 55.924  -31.080 126.891 1.00 55.34  ? 78  LEU D CB  1 
ATOM   8785  C CG  . LEU D 1 59  ? 57.292  -31.505 127.434 1.00 55.55  ? 78  LEU D CG  1 
ATOM   8786  C CD1 . LEU D 1 59  ? 58.426  -30.976 126.584 1.00 56.99  ? 78  LEU D CD1 1 
ATOM   8787  C CD2 . LEU D 1 59  ? 57.456  -31.052 128.871 1.00 54.21  ? 78  LEU D CD2 1 
ATOM   8788  N N   . GLU D 1 60  ? 52.557  -30.901 127.984 1.00 53.82  ? 79  GLU D N   1 
ATOM   8789  C CA  . GLU D 1 60  ? 51.212  -30.399 127.745 1.00 53.18  ? 79  GLU D CA  1 
ATOM   8790  C C   . GLU D 1 60  ? 51.209  -28.970 127.154 1.00 54.33  ? 79  GLU D C   1 
ATOM   8791  O O   . GLU D 1 60  ? 52.232  -28.284 127.048 1.00 55.49  ? 79  GLU D O   1 
ATOM   8792  C CB  . GLU D 1 60  ? 50.409  -30.426 129.056 1.00 51.21  ? 79  GLU D CB  1 
ATOM   8793  C CG  . GLU D 1 60  ? 49.441  -31.594 129.224 1.00 50.57  ? 79  GLU D CG  1 
ATOM   8794  C CD  . GLU D 1 60  ? 48.107  -31.397 128.498 1.00 51.28  ? 79  GLU D CD  1 
ATOM   8795  O OE1 . GLU D 1 60  ? 47.882  -30.298 127.928 1.00 52.25  ? 79  GLU D OE1 1 
ATOM   8796  O OE2 . GLU D 1 60  ? 47.274  -32.350 128.486 1.00 50.92  ? 79  GLU D OE2 1 
ATOM   8797  N N   . LYS D 1 61  ? 50.025  -28.536 126.740 1.00 54.02  ? 80  LYS D N   1 
ATOM   8798  C CA  . LYS D 1 61  ? 49.850  -27.153 126.321 1.00 54.73  ? 80  LYS D CA  1 
ATOM   8799  C C   . LYS D 1 61  ? 50.324  -26.210 127.423 1.00 54.51  ? 80  LYS D C   1 
ATOM   8800  O O   . LYS D 1 61  ? 50.308  -26.541 128.610 1.00 53.13  ? 80  LYS D O   1 
ATOM   8801  C CB  . LYS D 1 61  ? 48.379  -26.869 125.994 1.00 54.88  ? 80  LYS D CB  1 
ATOM   8802  C CG  . LYS D 1 61  ? 47.472  -26.953 127.220 1.00 53.92  ? 80  LYS D CG  1 
ATOM   8803  C CD  . LYS D 1 61  ? 46.017  -26.774 126.897 1.00 53.84  ? 80  LYS D CD  1 
ATOM   8804  C CE  . LYS D 1 61  ? 45.360  -28.093 126.567 1.00 53.98  ? 80  LYS D CE  1 
ATOM   8805  N NZ  . LYS D 1 61  ? 45.526  -29.076 127.642 1.00 53.15  ? 80  LYS D NZ  1 
ATOM   8806  N N   . GLY D 1 62  ? 50.745  -25.020 127.029 1.00 58.35  ? 81  GLY D N   1 
ATOM   8807  C CA  . GLY D 1 62  ? 51.138  -24.042 128.003 1.00 58.10  ? 81  GLY D CA  1 
ATOM   8808  C C   . GLY D 1 62  ? 52.511  -24.236 128.592 1.00 58.37  ? 81  GLY D C   1 
ATOM   8809  O O   . GLY D 1 62  ? 52.966  -23.376 129.373 1.00 58.87  ? 81  GLY D O   1 
ATOM   8810  N N   . HIS D 1 63  ? 53.206  -25.299 128.232 1.00 59.56  ? 82  HIS D N   1 
ATOM   8811  C CA  . HIS D 1 63  ? 54.510  -25.519 128.827 1.00 59.47  ? 82  HIS D CA  1 
ATOM   8812  C C   . HIS D 1 63  ? 55.453  -24.332 128.580 1.00 61.06  ? 82  HIS D C   1 
ATOM   8813  O O   . HIS D 1 63  ? 55.724  -23.958 127.435 1.00 62.68  ? 82  HIS D O   1 
ATOM   8814  C CB  . HIS D 1 63  ? 55.139  -26.793 128.291 1.00 59.87  ? 82  HIS D CB  1 
ATOM   8815  C CG  . HIS D 1 63  ? 56.385  -27.157 129.020 1.00 59.75  ? 82  HIS D CG  1 
ATOM   8816  N ND1 . HIS D 1 63  ? 56.360  -27.712 130.278 1.00 58.35  ? 82  HIS D ND1 1 
ATOM   8817  C CD2 . HIS D 1 63  ? 57.689  -26.979 128.710 1.00 61.17  ? 82  HIS D CD2 1 
ATOM   8818  C CE1 . HIS D 1 63  ? 57.601  -27.879 130.705 1.00 58.92  ? 82  HIS D CE1 1 
ATOM   8819  N NE2 . HIS D 1 63  ? 58.427  -27.447 129.770 1.00 60.53  ? 82  HIS D NE2 1 
ATOM   8820  N N   . ALA D 1 64  ? 55.959  -23.748 129.664 1.00 61.41  ? 83  ALA D N   1 
ATOM   8821  C CA  . ALA D 1 64  ? 57.054  -22.776 129.631 1.00 62.71  ? 83  ALA D CA  1 
ATOM   8822  C C   . ALA D 1 64  ? 56.680  -21.498 128.905 1.00 64.20  ? 83  ALA D C   1 
ATOM   8823  O O   . ALA D 1 64  ? 57.561  -20.771 128.411 1.00 66.11  ? 83  ALA D O   1 
ATOM   8824  C CB  . ALA D 1 64  ? 58.315  -23.376 128.988 1.00 64.24  ? 83  ALA D CB  1 
ATOM   8825  N N   . THR D 1 65  ? 55.386  -21.187 128.829 1.00 62.69  ? 84  THR D N   1 
ATOM   8826  C CA  . THR D 1 65  ? 54.992  -19.971 128.126 1.00 63.78  ? 84  THR D CA  1 
ATOM   8827  C C   . THR D 1 65  ? 55.329  -18.708 128.922 1.00 64.73  ? 84  THR D C   1 
ATOM   8828  O O   . THR D 1 65  ? 55.556  -17.656 128.319 1.00 67.38  ? 84  THR D O   1 
ATOM   8829  C CB  . THR D 1 65  ? 53.504  -20.056 127.788 1.00 63.32  ? 84  THR D CB  1 
ATOM   8830  O OG1 . THR D 1 65  ? 52.815  -20.729 128.850 1.00 61.57  ? 84  THR D OG1 1 
ATOM   8831  C CG2 . THR D 1 65  ? 53.309  -20.838 126.489 1.00 63.53  ? 84  THR D CG2 1 
ATOM   8832  N N   . ARG D 1 66  ? 55.388  -18.783 130.257 1.00 63.36  ? 85  ARG D N   1 
ATOM   8833  C CA  . ARG D 1 66  ? 55.719  -17.594 131.034 1.00 66.21  ? 85  ARG D CA  1 
ATOM   8834  C C   . ARG D 1 66  ? 57.023  -16.994 130.550 1.00 69.28  ? 85  ARG D C   1 
ATOM   8835  O O   . ARG D 1 66  ? 57.198  -15.777 130.566 1.00 72.35  ? 85  ARG D O   1 
ATOM   8836  C CB  . ARG D 1 66  ? 55.864  -17.900 132.527 1.00 66.27  ? 85  ARG D CB  1 
ATOM   8837  N N   . THR D 1 67  ? 57.943  -17.839 130.091 1.00 69.02  ? 86  THR D N   1 
ATOM   8838  C CA  . THR D 1 67  ? 59.241  -17.384 129.630 1.00 72.09  ? 86  THR D CA  1 
ATOM   8839  C C   . THR D 1 67  ? 59.453  -17.514 128.137 1.00 72.39  ? 86  THR D C   1 
ATOM   8840  O O   . THR D 1 67  ? 60.225  -16.748 127.577 1.00 75.39  ? 86  THR D O   1 
ATOM   8841  C CB  . THR D 1 67  ? 60.321  -18.174 130.349 1.00 72.31  ? 86  THR D CB  1 
ATOM   8842  O OG1 . THR D 1 67  ? 60.110  -19.549 130.041 1.00 69.23  ? 86  THR D OG1 1 
ATOM   8843  C CG2 . THR D 1 67  ? 60.195  -17.940 131.827 1.00 72.66  ? 86  THR D CG2 1 
ATOM   8844  N N   . HIS D 1 68  ? 58.781  -18.431 127.468 1.00 69.60  ? 87  HIS D N   1 
ATOM   8845  C CA  . HIS D 1 68  ? 59.011  -18.648 126.048 1.00 70.01  ? 87  HIS D CA  1 
ATOM   8846  C C   . HIS D 1 68  ? 57.866  -18.206 125.138 1.00 69.30  ? 87  HIS D C   1 
ATOM   8847  O O   . HIS D 1 68  ? 58.009  -18.304 123.918 1.00 69.99  ? 87  HIS D O   1 
ATOM   8848  C CB  . HIS D 1 68  ? 59.306  -20.135 125.806 1.00 67.88  ? 87  HIS D CB  1 
ATOM   8849  C CG  . HIS D 1 68  ? 60.671  -20.561 126.233 1.00 69.35  ? 87  HIS D CG  1 
ATOM   8850  N ND1 . HIS D 1 68  ? 61.110  -20.440 127.530 1.00 69.91  ? 87  HIS D ND1 1 
ATOM   8851  C CD2 . HIS D 1 68  ? 61.693  -21.103 125.532 1.00 70.58  ? 87  HIS D CD2 1 
ATOM   8852  C CE1 . HIS D 1 68  ? 62.344  -20.909 127.615 1.00 71.38  ? 87  HIS D CE1 1 
ATOM   8853  N NE2 . HIS D 1 68  ? 62.726  -21.305 126.414 1.00 71.84  ? 87  HIS D NE2 1 
ATOM   8854  N N   . GLY D 1 69  ? 56.737  -17.735 125.674 1.00 68.17  ? 88  GLY D N   1 
ATOM   8855  C CA  . GLY D 1 69  ? 55.662  -17.206 124.837 1.00 68.14  ? 88  GLY D CA  1 
ATOM   8856  C C   . GLY D 1 69  ? 54.749  -18.218 124.157 1.00 64.49  ? 88  GLY D C   1 
ATOM   8857  O O   . GLY D 1 69  ? 53.522  -18.182 124.325 1.00 64.61  ? 88  GLY D O   1 
ATOM   8858  N N   . THR D 1 70  ? 55.319  -19.132 123.384 1.00 65.52  ? 89  THR D N   1 
ATOM   8859  C CA  . THR D 1 70  ? 54.535  -20.132 122.683 1.00 64.48  ? 89  THR D CA  1 
ATOM   8860  C C   . THR D 1 70  ? 54.926  -21.519 123.152 1.00 63.37  ? 89  THR D C   1 
ATOM   8861  O O   . THR D 1 70  ? 56.108  -21.790 123.372 1.00 63.83  ? 89  THR D O   1 
ATOM   8862  C CB  . THR D 1 70  ? 54.745  -20.066 121.171 1.00 66.34  ? 89  THR D CB  1 
ATOM   8863  O OG1 . THR D 1 70  ? 56.115  -20.376 120.872 1.00 67.24  ? 89  THR D OG1 1 
ATOM   8864  C CG2 . THR D 1 70  ? 54.398  -18.693 120.643 1.00 67.78  ? 89  THR D CG2 1 
ATOM   8865  N N   . THR D 1 71  ? 53.920  -22.396 123.277 1.00 61.73  ? 90  THR D N   1 
ATOM   8866  C CA  . THR D 1 71  ? 54.144  -23.785 123.655 1.00 60.87  ? 90  THR D CA  1 
ATOM   8867  C C   . THR D 1 71  ? 55.189  -24.406 122.746 1.00 62.08  ? 90  THR D C   1 
ATOM   8868  O O   . THR D 1 71  ? 56.163  -25.002 123.215 1.00 62.22  ? 90  THR D O   1 
ATOM   8869  C CB  . THR D 1 71  ? 52.810  -24.533 123.596 1.00 59.79  ? 90  THR D CB  1 
ATOM   8870  O OG1 . THR D 1 71  ? 51.911  -23.968 124.563 1.00 58.84  ? 90  THR D OG1 1 
ATOM   8871  C CG2 . THR D 1 71  ? 52.947  -26.007 123.908 1.00 59.16  ? 90  THR D CG2 1 
ATOM   8872  N N   . GLU D 1 72  ? 55.032  -24.230 121.431 1.00 62.11  ? 91  GLU D N   1 
ATOM   8873  C CA  . GLU D 1 72  ? 55.993  -24.817 120.504 1.00 62.92  ? 91  GLU D CA  1 
ATOM   8874  C C   . GLU D 1 72  ? 57.417  -24.470 120.898 1.00 63.95  ? 91  GLU D C   1 
ATOM   8875  O O   . GLU D 1 72  ? 58.298  -25.335 120.906 1.00 64.22  ? 91  GLU D O   1 
ATOM   8876  C CB  . GLU D 1 72  ? 55.729  -24.352 119.077 1.00 64.16  ? 91  GLU D CB  1 
ATOM   8877  C CG  . GLU D 1 72  ? 54.385  -24.776 118.527 1.00 63.61  ? 91  GLU D CG  1 
ATOM   8878  C CD  . GLU D 1 72  ? 53.404  -23.636 118.522 1.00 63.12  ? 91  GLU D CD  1 
ATOM   8879  O OE1 . GLU D 1 72  ? 53.356  -22.917 119.547 1.00 63.09  ? 91  GLU D OE1 1 
ATOM   8880  O OE2 . GLU D 1 72  ? 52.708  -23.448 117.500 1.00 63.31  ? 91  GLU D OE2 1 
ATOM   8881  N N   . ALA D 1 73  ? 57.665  -23.214 121.255 1.00 63.76  ? 92  ALA D N   1 
ATOM   8882  C CA  . ALA D 1 73  ? 59.001  -22.863 121.722 1.00 64.60  ? 92  ALA D CA  1 
ATOM   8883  C C   . ALA D 1 73  ? 59.306  -23.509 123.066 1.00 63.39  ? 92  ALA D C   1 
ATOM   8884  O O   . ALA D 1 73  ? 60.418  -23.997 123.287 1.00 64.01  ? 92  ALA D O   1 
ATOM   8885  C CB  . ALA D 1 73  ? 59.148  -21.349 121.823 1.00 67.00  ? 92  ALA D CB  1 
ATOM   8886  N N   . GLY D 1 74  ? 58.327  -23.532 123.971 1.00 64.29  ? 93  GLY D N   1 
ATOM   8887  C CA  . GLY D 1 74  ? 58.564  -24.115 125.280 1.00 63.39  ? 93  GLY D CA  1 
ATOM   8888  C C   . GLY D 1 74  ? 58.916  -25.583 125.199 1.00 62.72  ? 93  GLY D C   1 
ATOM   8889  O O   . GLY D 1 74  ? 59.925  -26.034 125.737 1.00 62.95  ? 93  GLY D O   1 
ATOM   8890  N N   . ILE D 1 75  ? 58.083  -26.351 124.514 1.00 63.08  ? 94  ILE D N   1 
ATOM   8891  C CA  . ILE D 1 75  ? 58.343  -27.778 124.390 1.00 62.75  ? 94  ILE D CA  1 
ATOM   8892  C C   . ILE D 1 75  ? 59.667  -27.998 123.685 1.00 64.13  ? 94  ILE D C   1 
ATOM   8893  O O   . ILE D 1 75  ? 60.516  -28.759 124.152 1.00 64.31  ? 94  ILE D O   1 
ATOM   8894  C CB  . ILE D 1 75  ? 57.185  -28.479 123.661 1.00 62.01  ? 94  ILE D CB  1 
ATOM   8895  C CG1 . ILE D 1 75  ? 55.943  -28.495 124.562 1.00 60.71  ? 94  ILE D CG1 1 
ATOM   8896  C CG2 . ILE D 1 75  ? 57.597  -29.879 123.246 1.00 62.26  ? 94  ILE D CG2 1 
ATOM   8897  C CD1 . ILE D 1 75  ? 54.674  -29.071 123.901 1.00 60.28  ? 94  ILE D CD1 1 
ATOM   8898  N N   . GLU D 1 76  ? 59.890  -27.292 122.579 1.00 66.85  ? 95  GLU D N   1 
ATOM   8899  C CA  . GLU D 1 76  ? 61.115  -27.510 121.821 1.00 68.18  ? 95  GLU D CA  1 
ATOM   8900  C C   . GLU D 1 76  ? 62.350  -27.417 122.717 1.00 68.54  ? 95  GLU D C   1 
ATOM   8901  O O   . GLU D 1 76  ? 63.175  -28.333 122.741 1.00 69.10  ? 95  GLU D O   1 
ATOM   8902  C CB  . GLU D 1 76  ? 61.252  -26.509 120.675 1.00 69.81  ? 95  GLU D CB  1 
ATOM   8903  C CG  . GLU D 1 76  ? 62.674  -26.524 120.069 1.00 70.95  ? 95  GLU D CG  1 
ATOM   8904  C CD  . GLU D 1 76  ? 63.076  -27.882 119.477 1.00 71.22  ? 95  GLU D CD  1 
ATOM   8905  O OE1 . GLU D 1 76  ? 62.299  -28.869 119.579 1.00 75.36  ? 95  GLU D OE1 1 
ATOM   8906  O OE2 . GLU D 1 76  ? 64.189  -27.960 118.903 1.00 67.61  ? 95  GLU D OE2 1 
ATOM   8907  N N   . ALA D 1 77  ? 62.520  -26.284 123.423 1.00 66.47  ? 96  ALA D N   1 
ATOM   8908  C CA  . ALA D 1 77  ? 63.636  -26.148 124.357 1.00 66.93  ? 96  ALA D CA  1 
ATOM   8909  C C   . ALA D 1 77  ? 63.653  -27.282 125.383 1.00 65.83  ? 96  ALA D C   1 
ATOM   8910  O O   . ALA D 1 77  ? 64.710  -27.867 125.665 1.00 66.25  ? 96  ALA D O   1 
ATOM   8911  C CB  . ALA D 1 77  ? 63.559  -24.795 125.064 1.00 68.20  ? 96  ALA D CB  1 
ATOM   8912  N N   . GLU D 1 78  ? 62.493  -27.619 125.944 1.00 68.44  ? 97  GLU D N   1 
ATOM   8913  C CA  . GLU D 1 78  ? 62.438  -28.673 126.957 1.00 67.31  ? 97  GLU D CA  1 
ATOM   8914  C C   . GLU D 1 78  ? 62.939  -30.008 126.402 1.00 67.43  ? 97  GLU D C   1 
ATOM   8915  O O   . GLU D 1 78  ? 63.742  -30.702 127.035 1.00 67.80  ? 97  GLU D O   1 
ATOM   8916  C CB  . GLU D 1 78  ? 61.012  -28.789 127.479 1.00 65.94  ? 97  GLU D CB  1 
ATOM   8917  C CG  . GLU D 1 78  ? 60.904  -29.580 128.746 1.00 64.54  ? 97  GLU D CG  1 
ATOM   8918  C CD  . GLU D 1 78  ? 61.820  -29.058 129.826 1.00 64.89  ? 97  GLU D CD  1 
ATOM   8919  O OE1 . GLU D 1 78  ? 61.564  -27.929 130.341 1.00 64.59  ? 97  GLU D OE1 1 
ATOM   8920  O OE2 . GLU D 1 78  ? 62.831  -29.750 130.126 1.00 65.56  ? 97  GLU D OE2 1 
ATOM   8921  N N   . ALA D 1 79  ? 62.472  -30.385 125.210 1.00 65.77  ? 98  ALA D N   1 
ATOM   8922  C CA  . ALA D 1 79  ? 62.976  -31.597 124.572 1.00 66.09  ? 98  ALA D CA  1 
ATOM   8923  C C   . ALA D 1 79  ? 64.498  -31.589 124.514 1.00 67.16  ? 98  ALA D C   1 
ATOM   8924  O O   . ALA D 1 79  ? 65.141  -32.624 124.686 1.00 67.61  ? 98  ALA D O   1 
ATOM   8925  C CB  . ALA D 1 79  ? 62.381  -31.750 123.168 1.00 66.75  ? 98  ALA D CB  1 
ATOM   8926  N N   . ARG D 1 80  ? 65.102  -30.422 124.314 1.00 67.39  ? 99  ARG D N   1 
ATOM   8927  C CA  . ARG D 1 80  ? 66.554  -30.383 124.157 1.00 69.18  ? 99  ARG D CA  1 
ATOM   8928  C C   . ARG D 1 80  ? 67.278  -30.616 125.485 1.00 68.97  ? 99  ARG D C   1 
ATOM   8929  O O   . ARG D 1 80  ? 68.310  -31.297 125.509 1.00 69.90  ? 99  ARG D O   1 
ATOM   8930  C CB  . ARG D 1 80  ? 66.986  -29.058 123.521 1.00 71.37  ? 99  ARG D CB  1 
ATOM   8931  C CG  . ARG D 1 80  ? 66.953  -29.064 121.988 1.00 73.16  ? 99  ARG D CG  1 
ATOM   8932  C CD  . ARG D 1 80  ? 67.547  -27.767 121.413 1.00 76.60  ? 99  ARG D CD  1 
ATOM   8933  N NE  . ARG D 1 80  ? 66.580  -26.945 120.684 1.00 77.43  ? 99  ARG D NE  1 
ATOM   8934  C CZ  . ARG D 1 80  ? 66.703  -25.638 120.477 1.00 81.34  ? 99  ARG D CZ  1 
ATOM   8935  N NH1 . ARG D 1 80  ? 67.718  -24.950 120.975 1.00 84.84  ? 99  ARG D NH1 1 
ATOM   8936  N NH2 . ARG D 1 80  ? 65.792  -25.008 119.734 1.00 81.90  ? 99  ARG D NH2 1 
ATOM   8937  N N   . GLN D 1 81  ? 66.776  -30.067 126.601 1.00 69.92  ? 100 GLN D N   1 
ATOM   8938  C CA  . GLN D 1 81  ? 67.518  -30.287 127.841 1.00 69.97  ? 100 GLN D CA  1 
ATOM   8939  C C   . GLN D 1 81  ? 67.242  -31.677 128.408 1.00 68.81  ? 100 GLN D C   1 
ATOM   8940  O O   . GLN D 1 81  ? 68.142  -32.317 128.960 1.00 69.40  ? 100 GLN D O   1 
ATOM   8941  C CB  . GLN D 1 81  ? 67.210  -29.210 128.875 1.00 70.89  ? 100 GLN D CB  1 
ATOM   8942  C CG  . GLN D 1 81  ? 65.947  -29.392 129.664 1.00 68.91  ? 100 GLN D CG  1 
ATOM   8943  C CD  . GLN D 1 81  ? 65.967  -28.509 130.899 1.00 69.31  ? 100 GLN D CD  1 
ATOM   8944  O OE1 . GLN D 1 81  ? 67.031  -28.266 131.475 1.00 72.56  ? 100 GLN D OE1 1 
ATOM   8945  N NE2 . GLN D 1 81  ? 64.804  -28.004 131.300 1.00 67.11  ? 100 GLN D NE2 1 
ATOM   8946  N N   . LEU D 1 82  ? 66.006  -32.161 128.299 1.00 68.53  ? 101 LEU D N   1 
ATOM   8947  C CA  . LEU D 1 82  ? 65.729  -33.525 128.739 1.00 67.46  ? 101 LEU D CA  1 
ATOM   8948  C C   . LEU D 1 82  ? 66.606  -34.528 127.993 1.00 68.35  ? 101 LEU D C   1 
ATOM   8949  O O   . LEU D 1 82  ? 67.179  -35.444 128.585 1.00 68.16  ? 101 LEU D O   1 
ATOM   8950  C CB  . LEU D 1 82  ? 64.260  -33.856 128.533 1.00 66.22  ? 101 LEU D CB  1 
ATOM   8951  C CG  . LEU D 1 82  ? 63.281  -33.275 129.543 1.00 64.90  ? 101 LEU D CG  1 
ATOM   8952  C CD1 . LEU D 1 82  ? 61.852  -33.395 128.943 1.00 64.35  ? 101 LEU D CD1 1 
ATOM   8953  C CD2 . LEU D 1 82  ? 63.354  -33.953 130.901 1.00 64.24  ? 101 LEU D CD2 1 
ATOM   8954  N N   . LYS D 1 83  ? 66.708  -34.376 126.677 1.00 64.88  ? 102 LYS D N   1 
ATOM   8955  C CA  . LYS D 1 83  ? 67.530  -35.284 125.890 1.00 65.99  ? 102 LYS D CA  1 
ATOM   8956  C C   . LYS D 1 83  ? 69.011  -35.129 126.210 1.00 67.47  ? 102 LYS D C   1 
ATOM   8957  O O   . LYS D 1 83  ? 69.756  -36.109 126.146 1.00 68.25  ? 102 LYS D O   1 
ATOM   8958  C CB  . LYS D 1 83  ? 67.274  -35.056 124.398 1.00 67.32  ? 102 LYS D CB  1 
ATOM   8959  C CG  . LYS D 1 83  ? 65.931  -35.611 123.864 1.00 66.75  ? 102 LYS D CG  1 
ATOM   8960  C CD  . LYS D 1 83  ? 65.917  -35.622 122.324 1.00 68.62  ? 102 LYS D CD  1 
ATOM   8961  C CE  . LYS D 1 83  ? 64.612  -36.098 121.711 1.00 67.68  ? 102 LYS D CE  1 
ATOM   8962  N NZ  . LYS D 1 83  ? 63.529  -36.235 122.719 1.00 65.66  ? 102 LYS D NZ  1 
ATOM   8963  N N   . ASN D 1 84  ? 69.468  -33.919 126.549 1.00 66.29  ? 103 ASN D N   1 
ATOM   8964  C CA  . ASN D 1 84  ? 70.875  -33.753 126.918 1.00 71.55  ? 103 ASN D CA  1 
ATOM   8965  C C   . ASN D 1 84  ? 71.210  -34.525 128.195 1.00 70.78  ? 103 ASN D C   1 
ATOM   8966  O O   . ASN D 1 84  ? 72.340  -34.981 128.357 1.00 73.02  ? 103 ASN D O   1 
ATOM   8967  C CB  . ASN D 1 84  ? 71.217  -32.264 127.065 1.00 73.93  ? 103 ASN D CB  1 
ATOM   8968  N N   . LEU D 1 85  ? 70.253  -34.685 129.107 1.00 71.59  ? 104 LEU D N   1 
ATOM   8969  C CA  . LEU D 1 85  ? 70.468  -35.519 130.282 1.00 70.90  ? 104 LEU D CA  1 
ATOM   8970  C C   . LEU D 1 85  ? 70.178  -36.993 130.015 1.00 69.70  ? 104 LEU D C   1 
ATOM   8971  O O   . LEU D 1 85  ? 70.873  -37.846 130.559 1.00 70.65  ? 104 LEU D O   1 
ATOM   8972  C CB  . LEU D 1 85  ? 69.605  -35.030 131.452 1.00 68.89  ? 104 LEU D CB  1 
ATOM   8973  N N   . ASN D 1 86  ? 69.200  -37.315 129.170 1.00 67.49  ? 105 ASN D N   1 
ATOM   8974  C CA  . ASN D 1 86  ? 68.822  -38.697 128.875 1.00 66.72  ? 105 ASN D CA  1 
ATOM   8975  C C   . ASN D 1 86  ? 68.531  -38.805 127.380 1.00 67.09  ? 105 ASN D C   1 
ATOM   8976  O O   . ASN D 1 86  ? 67.427  -38.469 126.923 1.00 65.80  ? 105 ASN D O   1 
ATOM   8977  C CB  . ASN D 1 86  ? 67.603  -39.124 129.696 1.00 64.24  ? 105 ASN D CB  1 
ATOM   8978  C CG  . ASN D 1 86  ? 66.986  -40.440 129.216 1.00 63.30  ? 105 ASN D CG  1 
ATOM   8979  O OD1 . ASN D 1 86  ? 67.533  -41.123 128.369 1.00 64.62  ? 105 ASN D OD1 1 
ATOM   8980  N ND2 . ASN D 1 86  ? 65.835  -40.798 129.786 1.00 60.73  ? 105 ASN D ND2 1 
ATOM   8981  N N   . PRO D 1 87  ? 69.491  -39.284 126.591 1.00 66.88  ? 106 PRO D N   1 
ATOM   8982  C CA  . PRO D 1 87  ? 69.289  -39.359 125.134 1.00 67.58  ? 106 PRO D CA  1 
ATOM   8983  C C   . PRO D 1 87  ? 68.265  -40.375 124.701 1.00 65.38  ? 106 PRO D C   1 
ATOM   8984  O O   . PRO D 1 87  ? 67.832  -40.327 123.541 1.00 65.98  ? 106 PRO D O   1 
ATOM   8985  C CB  . PRO D 1 87  ? 70.676  -39.734 124.589 1.00 71.82  ? 106 PRO D CB  1 
ATOM   8986  C CG  . PRO D 1 87  ? 71.527  -40.033 125.758 1.00 73.77  ? 106 PRO D CG  1 
ATOM   8987  C CD  . PRO D 1 87  ? 70.913  -39.442 126.979 1.00 70.50  ? 106 PRO D CD  1 
ATOM   8988  N N   . LYS D 1 88  ? 67.874  -41.298 125.577 1.00 65.90  ? 107 LYS D N   1 
ATOM   8989  C CA  . LYS D 1 88  ? 66.822  -42.256 125.271 1.00 64.08  ? 107 LYS D CA  1 
ATOM   8990  C C   . LYS D 1 88  ? 65.427  -41.686 125.449 1.00 62.05  ? 107 LYS D C   1 
ATOM   8991  O O   . LYS D 1 88  ? 64.446  -42.382 125.162 1.00 60.65  ? 107 LYS D O   1 
ATOM   8992  C CB  . LYS D 1 88  ? 66.954  -43.471 126.180 1.00 64.42  ? 107 LYS D CB  1 
ATOM   8993  C CG  . LYS D 1 88  ? 68.196  -44.274 125.946 1.00 67.17  ? 107 LYS D CG  1 
ATOM   8994  C CD  . LYS D 1 88  ? 68.049  -45.612 126.634 1.00 66.94  ? 107 LYS D CD  1 
ATOM   8995  C CE  . LYS D 1 88  ? 69.016  -46.656 126.090 1.00 69.17  ? 107 LYS D CE  1 
ATOM   8996  N NZ  . LYS D 1 88  ? 69.451  -46.398 124.689 1.00 69.92  ? 107 LYS D NZ  1 
ATOM   8997  N N   . MET D 1 89  ? 65.313  -40.466 125.951 1.00 64.43  ? 108 MET D N   1 
ATOM   8998  C CA  . MET D 1 89  ? 64.002  -39.941 126.264 1.00 62.46  ? 108 MET D CA  1 
ATOM   8999  C C   . MET D 1 89  ? 63.261  -39.633 124.985 1.00 61.79  ? 108 MET D C   1 
ATOM   9000  O O   . MET D 1 89  ? 63.823  -39.042 124.054 1.00 63.84  ? 108 MET D O   1 
ATOM   9001  C CB  . MET D 1 89  ? 64.088  -38.702 127.126 1.00 63.26  ? 108 MET D CB  1 
ATOM   9002  C CG  . MET D 1 89  ? 62.997  -38.762 128.147 1.00 61.53  ? 108 MET D CG  1 
ATOM   9003  S SD  . MET D 1 89  ? 63.138  -37.527 129.451 1.00 61.91  ? 108 MET D SD  1 
ATOM   9004  C CE  . MET D 1 89  ? 61.823  -38.194 130.509 1.00 59.11  ? 108 MET D CE  1 
ATOM   9005  N N   . LYS D 1 90  ? 62.015  -40.089 124.935 1.00 58.73  ? 109 LYS D N   1 
ATOM   9006  C CA  . LYS D 1 90  ? 61.079  -39.778 123.872 1.00 57.32  ? 109 LYS D CA  1 
ATOM   9007  C C   . LYS D 1 90  ? 60.167  -38.689 124.411 1.00 55.90  ? 109 LYS D C   1 
ATOM   9008  O O   . LYS D 1 90  ? 59.433  -38.913 125.383 1.00 54.75  ? 109 LYS D O   1 
ATOM   9009  C CB  . LYS D 1 90  ? 60.272  -41.004 123.463 1.00 56.08  ? 109 LYS D CB  1 
ATOM   9010  C CG  . LYS D 1 90  ? 61.089  -42.119 122.897 1.00 57.72  ? 109 LYS D CG  1 
ATOM   9011  C CD  . LYS D 1 90  ? 61.732  -41.745 121.593 1.00 59.15  ? 109 LYS D CD  1 
ATOM   9012  C CE  . LYS D 1 90  ? 62.472  -42.947 121.063 1.00 60.61  ? 109 LYS D CE  1 
ATOM   9013  N NZ  . LYS D 1 90  ? 63.192  -42.721 119.798 1.00 62.28  ? 109 LYS D NZ  1 
ATOM   9014  N N   . VAL D 1 91  ? 60.230  -37.514 123.786 1.00 57.81  ? 110 VAL D N   1 
ATOM   9015  C CA  . VAL D 1 91  ? 59.510  -36.308 124.201 1.00 56.80  ? 110 VAL D CA  1 
ATOM   9016  C C   . VAL D 1 91  ? 58.421  -36.040 123.160 1.00 55.19  ? 110 VAL D C   1 
ATOM   9017  O O   . VAL D 1 91  ? 58.701  -35.945 121.959 1.00 55.85  ? 110 VAL D O   1 
ATOM   9018  C CB  . VAL D 1 91  ? 60.473  -35.117 124.347 1.00 58.85  ? 110 VAL D CB  1 
ATOM   9019  C CG1 . VAL D 1 91  ? 59.781  -33.888 124.906 1.00 58.18  ? 110 VAL D CG1 1 
ATOM   9020  C CG2 . VAL D 1 91  ? 61.639  -35.503 125.247 1.00 60.69  ? 110 VAL D CG2 1 
ATOM   9021  N N   . ILE D 1 92  ? 57.180  -35.937 123.620 1.00 54.80  ? 111 ILE D N   1 
ATOM   9022  C CA  . ILE D 1 92  ? 56.015  -35.986 122.752 1.00 52.85  ? 111 ILE D CA  1 
ATOM   9023  C C   . ILE D 1 92  ? 55.318  -34.631 122.767 1.00 52.18  ? 111 ILE D C   1 
ATOM   9024  O O   . ILE D 1 92  ? 54.952  -34.108 123.830 1.00 51.95  ? 111 ILE D O   1 
ATOM   9025  C CB  . ILE D 1 92  ? 55.049  -37.111 123.171 1.00 50.69  ? 111 ILE D CB  1 
ATOM   9026  C CG1 . ILE D 1 92  ? 55.785  -38.461 123.282 1.00 51.91  ? 111 ILE D CG1 1 
ATOM   9027  C CG2 . ILE D 1 92  ? 53.880  -37.218 122.175 1.00 48.36  ? 111 ILE D CG2 1 
ATOM   9028  C CD1 . ILE D 1 92  ? 56.445  -38.941 121.990 1.00 53.50  ? 111 ILE D CD1 1 
ATOM   9029  N N   . PHE D 1 93  ? 55.096  -34.090 121.577 1.00 52.95  ? 112 PHE D N   1 
ATOM   9030  C CA  . PHE D 1 93  ? 54.528  -32.758 121.450 1.00 52.91  ? 112 PHE D CA  1 
ATOM   9031  C C   . PHE D 1 93  ? 53.009  -32.825 121.539 1.00 50.21  ? 112 PHE D C   1 
ATOM   9032  O O   . PHE D 1 93  ? 52.366  -33.590 120.810 1.00 49.22  ? 112 PHE D O   1 
ATOM   9033  C CB  . PHE D 1 93  ? 54.991  -32.130 120.130 1.00 54.56  ? 112 PHE D CB  1 
ATOM   9034  C CG  . PHE D 1 93  ? 54.332  -30.837 119.806 1.00 54.93  ? 112 PHE D CG  1 
ATOM   9035  C CD1 . PHE D 1 93  ? 54.601  -29.720 120.551 1.00 56.46  ? 112 PHE D CD1 1 
ATOM   9036  C CD2 . PHE D 1 93  ? 53.444  -30.749 118.758 1.00 54.71  ? 112 PHE D CD2 1 
ATOM   9037  C CE1 . PHE D 1 93  ? 53.996  -28.532 120.262 1.00 56.92  ? 112 PHE D CE1 1 
ATOM   9038  C CE2 . PHE D 1 93  ? 52.832  -29.562 118.462 1.00 55.54  ? 112 PHE D CE2 1 
ATOM   9039  C CZ  . PHE D 1 93  ? 53.109  -28.450 119.215 1.00 56.32  ? 112 PHE D CZ  1 
ATOM   9040  N N   . TYR D 1 94  ? 52.445  -32.035 122.454 1.00 51.87  ? 113 TYR D N   1 
ATOM   9041  C CA  . TYR D 1 94  ? 51.006  -32.000 122.627 1.00 50.10  ? 113 TYR D CA  1 
ATOM   9042  C C   . TYR D 1 94  ? 50.398  -31.137 121.539 1.00 50.89  ? 113 TYR D C   1 
ATOM   9043  O O   . TYR D 1 94  ? 50.804  -29.982 121.341 1.00 52.78  ? 113 TYR D O   1 
ATOM   9044  C CB  . TYR D 1 94  ? 50.622  -31.434 123.988 1.00 50.05  ? 113 TYR D CB  1 
ATOM   9045  C CG  . TYR D 1 94  ? 49.127  -31.382 124.216 1.00 48.63  ? 113 TYR D CG  1 
ATOM   9046  C CD1 . TYR D 1 94  ? 48.369  -30.340 123.706 1.00 49.45  ? 113 TYR D CD1 1 
ATOM   9047  C CD2 . TYR D 1 94  ? 48.471  -32.393 124.931 1.00 46.81  ? 113 TYR D CD2 1 
ATOM   9048  C CE1 . TYR D 1 94  ? 47.020  -30.300 123.896 1.00 48.65  ? 113 TYR D CE1 1 
ATOM   9049  C CE2 . TYR D 1 94  ? 47.107  -32.346 125.135 1.00 45.90  ? 113 TYR D CE2 1 
ATOM   9050  C CZ  . TYR D 1 94  ? 46.395  -31.291 124.615 1.00 46.84  ? 113 TYR D CZ  1 
ATOM   9051  O OH  . TYR D 1 94  ? 45.043  -31.227 124.787 1.00 46.71  ? 113 TYR D OH  1 
ATOM   9052  N N   . TRP D 1 95  ? 49.421  -31.687 120.826 1.00 48.30  ? 114 TRP D N   1 
ATOM   9053  C CA  . TRP D 1 95  ? 48.801  -30.946 119.722 1.00 49.12  ? 114 TRP D CA  1 
ATOM   9054  C C   . TRP D 1 95  ? 47.363  -31.431 119.656 1.00 47.83  ? 114 TRP D C   1 
ATOM   9055  O O   . TRP D 1 95  ? 47.108  -32.530 119.176 1.00 46.63  ? 114 TRP D O   1 
ATOM   9056  C CB  . TRP D 1 95  ? 49.552  -31.184 118.422 1.00 50.47  ? 114 TRP D CB  1 
ATOM   9057  C CG  . TRP D 1 95  ? 49.166  -30.299 117.254 1.00 51.74  ? 114 TRP D CG  1 
ATOM   9058  C CD1 . TRP D 1 95  ? 49.182  -30.662 115.937 1.00 52.06  ? 114 TRP D CD1 1 
ATOM   9059  C CD2 . TRP D 1 95  ? 48.721  -28.927 117.280 1.00 53.13  ? 114 TRP D CD2 1 
ATOM   9060  N NE1 . TRP D 1 95  ? 48.770  -29.615 115.148 1.00 53.77  ? 114 TRP D NE1 1 
ATOM   9061  C CE2 . TRP D 1 95  ? 48.484  -28.541 115.949 1.00 54.40  ? 114 TRP D CE2 1 
ATOM   9062  C CE3 . TRP D 1 95  ? 48.494  -27.999 118.296 1.00 53.68  ? 114 TRP D CE3 1 
ATOM   9063  C CZ2 . TRP D 1 95  ? 48.036  -27.271 115.613 1.00 56.18  ? 114 TRP D CZ2 1 
ATOM   9064  C CZ3 . TRP D 1 95  ? 48.041  -26.759 117.965 1.00 55.53  ? 114 TRP D CZ3 1 
ATOM   9065  C CH2 . TRP D 1 95  ? 47.819  -26.404 116.636 1.00 56.72  ? 114 TRP D CH2 1 
ATOM   9066  N N   . ASN D 1 96  ? 46.440  -30.638 120.171 1.00 44.20  ? 115 ASN D N   1 
ATOM   9067  C CA  . ASN D 1 96  ? 45.057  -31.090 120.255 1.00 43.23  ? 115 ASN D CA  1 
ATOM   9068  C C   . ASN D 1 96  ? 44.476  -31.304 118.861 1.00 43.57  ? 115 ASN D C   1 
ATOM   9069  O O   . ASN D 1 96  ? 44.727  -30.533 117.938 1.00 45.20  ? 115 ASN D O   1 
ATOM   9070  C CB  . ASN D 1 96  ? 44.243  -30.091 121.046 1.00 44.17  ? 115 ASN D CB  1 
ATOM   9071  C CG  . ASN D 1 96  ? 42.967  -30.667 121.547 1.00 43.41  ? 115 ASN D CG  1 
ATOM   9072  O OD1 . ASN D 1 96  ? 42.046  -30.896 120.772 1.00 43.73  ? 115 ASN D OD1 1 
ATOM   9073  N ND2 . ASN D 1 96  ? 42.900  -30.932 122.847 1.00 42.57  ? 115 ASN D ND2 1 
ATOM   9074  N N   . THR D 1 97  ? 43.734  -32.396 118.699 1.00 42.35  ? 116 THR D N   1 
ATOM   9075  C CA  . THR D 1 97  ? 43.200  -32.760 117.391 1.00 42.44  ? 116 THR D CA  1 
ATOM   9076  C C   . THR D 1 97  ? 41.924  -31.995 117.071 1.00 44.33  ? 116 THR D C   1 
ATOM   9077  O O   . THR D 1 97  ? 41.499  -31.959 115.913 1.00 45.48  ? 116 THR D O   1 
ATOM   9078  C CB  . THR D 1 97  ? 42.897  -34.266 117.334 1.00 40.03  ? 116 THR D CB  1 
ATOM   9079  O OG1 . THR D 1 97  ? 43.901  -35.015 118.025 1.00 38.41  ? 116 THR D OG1 1 
ATOM   9080  C CG2 . THR D 1 97  ? 42.815  -34.790 115.884 1.00 40.64  ? 116 THR D CG2 1 
ATOM   9081  N N   . PHE D 1 98  ? 41.317  -31.390 118.089 1.00 40.26  ? 117 PHE D N   1 
ATOM   9082  C CA  . PHE D 1 98  ? 39.961  -30.866 118.012 1.00 41.77  ? 117 PHE D CA  1 
ATOM   9083  C C   . PHE D 1 98  ? 39.836  -29.400 118.459 1.00 43.17  ? 117 PHE D C   1 
ATOM   9084  O O   . PHE D 1 98  ? 38.902  -28.725 118.007 1.00 44.46  ? 117 PHE D O   1 
ATOM   9085  C CB  . PHE D 1 98  ? 39.011  -31.762 118.842 1.00 41.03  ? 117 PHE D CB  1 
ATOM   9086  C CG  . PHE D 1 98  ? 37.548  -31.660 118.450 1.00 42.46  ? 117 PHE D CG  1 
ATOM   9087  C CD1 . PHE D 1 98  ? 37.156  -31.293 117.149 1.00 43.74  ? 117 PHE D CD1 1 
ATOM   9088  C CD2 . PHE D 1 98  ? 36.560  -31.882 119.397 1.00 42.41  ? 117 PHE D CD2 1 
ATOM   9089  C CE1 . PHE D 1 98  ? 35.822  -31.189 116.818 1.00 44.89  ? 117 PHE D CE1 1 
ATOM   9090  C CE2 . PHE D 1 98  ? 35.210  -31.759 119.062 1.00 43.21  ? 117 PHE D CE2 1 
ATOM   9091  C CZ  . PHE D 1 98  ? 34.847  -31.430 117.768 1.00 44.77  ? 117 PHE D CZ  1 
ATOM   9092  N N   . LEU D 1 99  ? 40.748  -28.881 119.283 1.00 46.74  ? 118 LEU D N   1 
ATOM   9093  C CA  . LEU D 1 99  ? 40.512  -27.621 119.955 1.00 47.49  ? 118 LEU D CA  1 
ATOM   9094  C C   . LEU D 1 99  ? 41.628  -26.631 119.694 1.00 48.50  ? 118 LEU D C   1 
ATOM   9095  O O   . LEU D 1 99  ? 42.816  -26.980 119.683 1.00 48.05  ? 118 LEU D O   1 
ATOM   9096  C CB  . LEU D 1 99  ? 40.369  -27.799 121.450 1.00 46.53  ? 118 LEU D CB  1 
ATOM   9097  C CG  . LEU D 1 99  ? 39.298  -28.787 121.875 1.00 45.87  ? 118 LEU D CG  1 
ATOM   9098  C CD1 . LEU D 1 99  ? 39.290  -28.885 123.401 1.00 44.83  ? 118 LEU D CD1 1 
ATOM   9099  C CD2 . LEU D 1 99  ? 37.923  -28.430 121.356 1.00 46.90  ? 118 LEU D CD2 1 
ATOM   9100  N N   . ASP D 1 100 ? 41.199  -25.392 119.488 1.00 50.55  ? 119 ASP D N   1 
ATOM   9101  C CA  . ASP D 1 100 ? 42.048  -24.287 119.068 1.00 51.70  ? 119 ASP D CA  1 
ATOM   9102  C C   . ASP D 1 100 ? 42.511  -23.530 120.316 1.00 51.53  ? 119 ASP D C   1 
ATOM   9103  O O   . ASP D 1 100 ? 42.037  -22.442 120.640 1.00 52.76  ? 119 ASP D O   1 
ATOM   9104  C CB  . ASP D 1 100 ? 41.270  -23.395 118.111 1.00 53.32  ? 119 ASP D CB  1 
ATOM   9105  C CG  . ASP D 1 100 ? 41.866  -22.007 117.989 1.00 54.95  ? 119 ASP D CG  1 
ATOM   9106  O OD1 . ASP D 1 100 ? 43.116  -21.936 117.879 1.00 55.09  ? 119 ASP D OD1 1 
ATOM   9107  O OD2 . ASP D 1 100 ? 41.105  -21.016 118.028 1.00 55.94  ? 119 ASP D OD2 1 
ATOM   9108  N N   . TYR D 1 101 ? 43.447  -24.139 121.036 1.00 50.68  ? 120 TYR D N   1 
ATOM   9109  C CA  . TYR D 1 101 ? 43.983  -23.495 122.222 1.00 50.61  ? 120 TYR D CA  1 
ATOM   9110  C C   . TYR D 1 101 ? 44.823  -22.274 121.841 1.00 52.27  ? 120 TYR D C   1 
ATOM   9111  O O   . TYR D 1 101 ? 45.508  -22.243 120.815 1.00 53.22  ? 120 TYR D O   1 
ATOM   9112  C CB  . TYR D 1 101 ? 44.808  -24.500 123.015 1.00 49.28  ? 120 TYR D CB  1 
ATOM   9113  C CG  . TYR D 1 101 ? 43.936  -25.377 123.874 1.00 47.66  ? 120 TYR D CG  1 
ATOM   9114  C CD1 . TYR D 1 101 ? 43.311  -24.856 124.997 1.00 47.70  ? 120 TYR D CD1 1 
ATOM   9115  C CD2 . TYR D 1 101 ? 43.725  -26.743 123.550 1.00 46.79  ? 120 TYR D CD2 1 
ATOM   9116  C CE1 . TYR D 1 101 ? 42.506  -25.630 125.782 1.00 46.46  ? 120 TYR D CE1 1 
ATOM   9117  C CE2 . TYR D 1 101 ? 42.913  -27.551 124.352 1.00 45.60  ? 120 TYR D CE2 1 
ATOM   9118  C CZ  . TYR D 1 101 ? 42.296  -26.985 125.456 1.00 45.36  ? 120 TYR D CZ  1 
ATOM   9119  O OH  . TYR D 1 101 ? 41.489  -27.734 126.256 1.00 44.48  ? 120 TYR D OH  1 
ATOM   9120  N N   . SER D 1 102 ? 44.767  -21.250 122.690 1.00 54.26  ? 121 SER D N   1 
ATOM   9121  C CA  . SER D 1 102 ? 45.354  -19.968 122.283 1.00 56.36  ? 121 SER D CA  1 
ATOM   9122  C C   . SER D 1 102 ? 46.863  -19.890 122.502 1.00 56.95  ? 121 SER D C   1 
ATOM   9123  O O   . SER D 1 102 ? 47.509  -19.056 121.887 1.00 59.32  ? 121 SER D O   1 
ATOM   9124  C CB  . SER D 1 102 ? 44.691  -18.793 123.015 1.00 57.35  ? 121 SER D CB  1 
ATOM   9125  O OG  . SER D 1 102 ? 45.009  -18.838 124.399 1.00 56.91  ? 121 SER D OG  1 
ATOM   9126  N N   . MET D 1 103 ? 47.452  -20.767 123.315 1.00 58.09  ? 122 MET D N   1 
ATOM   9127  C CA  . MET D 1 103 ? 48.839  -20.600 123.742 1.00 58.84  ? 122 MET D CA  1 
ATOM   9128  C C   . MET D 1 103 ? 49.842  -21.319 122.838 1.00 59.29  ? 122 MET D C   1 
ATOM   9129  O O   . MET D 1 103 ? 50.939  -21.690 123.295 1.00 59.45  ? 122 MET D O   1 
ATOM   9130  C CB  . MET D 1 103 ? 48.976  -21.055 125.196 1.00 58.04  ? 122 MET D CB  1 
ATOM   9131  C CG  . MET D 1 103 ? 48.851  -22.542 125.415 1.00 57.02  ? 122 MET D CG  1 
ATOM   9132  S SD  . MET D 1 103 ? 47.167  -23.223 125.592 1.00 55.08  ? 122 MET D SD  1 
ATOM   9133  C CE  . MET D 1 103 ? 46.358  -22.098 126.697 1.00 55.67  ? 122 MET D CE  1 
ATOM   9134  N N   . PHE D 1 104 ? 49.501  -21.499 121.564 1.00 59.24  ? 123 PHE D N   1 
ATOM   9135  C CA  . PHE D 1 104 ? 50.406  -22.003 120.539 1.00 59.93  ? 123 PHE D CA  1 
ATOM   9136  C C   . PHE D 1 104 ? 50.539  -20.956 119.435 1.00 61.92  ? 123 PHE D C   1 
ATOM   9137  O O   . PHE D 1 104 ? 49.538  -20.360 119.032 1.00 62.53  ? 123 PHE D O   1 
ATOM   9138  C CB  . PHE D 1 104 ? 49.886  -23.321 119.892 1.00 58.53  ? 123 PHE D CB  1 
ATOM   9139  C CG  . PHE D 1 104 ? 49.785  -24.487 120.831 1.00 56.30  ? 123 PHE D CG  1 
ATOM   9140  C CD1 . PHE D 1 104 ? 48.803  -24.544 121.799 1.00 55.08  ? 123 PHE D CD1 1 
ATOM   9141  C CD2 . PHE D 1 104 ? 50.661  -25.567 120.709 1.00 56.08  ? 123 PHE D CD2 1 
ATOM   9142  C CE1 . PHE D 1 104 ? 48.709  -25.654 122.661 1.00 53.51  ? 123 PHE D CE1 1 
ATOM   9143  C CE2 . PHE D 1 104 ? 50.587  -26.685 121.572 1.00 54.34  ? 123 PHE D CE2 1 
ATOM   9144  C CZ  . PHE D 1 104 ? 49.609  -26.726 122.547 1.00 53.05  ? 123 PHE D CZ  1 
ATOM   9145  N N   . ALA D 1 105 ? 51.753  -20.762 118.903 1.00 61.84  ? 124 ALA D N   1 
ATOM   9146  C CA  . ALA D 1 105 ? 51.923  -19.866 117.757 1.00 65.80  ? 124 ALA D CA  1 
ATOM   9147  C C   . ALA D 1 105 ? 50.950  -20.204 116.634 1.00 65.28  ? 124 ALA D C   1 
ATOM   9148  O O   . ALA D 1 105 ? 50.498  -19.320 115.897 1.00 67.89  ? 124 ALA D O   1 
ATOM   9149  C CB  . ALA D 1 105 ? 53.359  -19.937 117.231 1.00 68.70  ? 124 ALA D CB  1 
ATOM   9150  N N   . ALA D 1 106 ? 50.623  -21.484 116.491 1.00 63.06  ? 125 ALA D N   1 
ATOM   9151  C CA  . ALA D 1 106 ? 49.690  -21.917 115.461 1.00 62.56  ? 125 ALA D CA  1 
ATOM   9152  C C   . ALA D 1 106 ? 48.364  -21.190 115.573 1.00 62.20  ? 125 ALA D C   1 
ATOM   9153  O O   . ALA D 1 106 ? 47.709  -20.931 114.556 1.00 63.73  ? 125 ALA D O   1 
ATOM   9154  C CB  . ALA D 1 106 ? 49.480  -23.435 115.572 1.00 59.73  ? 125 ALA D CB  1 
ATOM   9155  N N   . HIS D 1 107 ? 47.950  -20.877 116.801 1.00 59.78  ? 126 HIS D N   1 
ATOM   9156  C CA  . HIS D 1 107 ? 46.656  -20.257 117.018 1.00 59.41  ? 126 HIS D CA  1 
ATOM   9157  C C   . HIS D 1 107 ? 46.480  -18.998 116.175 1.00 63.53  ? 126 HIS D C   1 
ATOM   9158  O O   . HIS D 1 107 ? 45.412  -18.772 115.595 1.00 64.00  ? 126 HIS D O   1 
ATOM   9159  C CB  . HIS D 1 107 ? 46.502  -19.921 118.491 1.00 57.86  ? 126 HIS D CB  1 
ATOM   9160  C CG  . HIS D 1 107 ? 45.288  -19.112 118.783 1.00 58.05  ? 126 HIS D CG  1 
ATOM   9161  N ND1 . HIS D 1 107 ? 44.020  -19.636 118.676 1.00 56.77  ? 126 HIS D ND1 1 
ATOM   9162  C CD2 . HIS D 1 107 ? 45.135  -17.822 119.159 1.00 60.44  ? 126 HIS D CD2 1 
ATOM   9163  C CE1 . HIS D 1 107 ? 43.137  -18.709 118.988 1.00 57.35  ? 126 HIS D CE1 1 
ATOM   9164  N NE2 . HIS D 1 107 ? 43.786  -17.596 119.277 1.00 59.67  ? 126 HIS D NE2 1 
ATOM   9165  N N   . LYS D 1 108 ? 47.514  -18.163 116.105 1.00 66.68  ? 127 LYS D N   1 
ATOM   9166  C CA  . LYS D 1 108 ? 47.430  -16.955 115.294 1.00 70.87  ? 127 LYS D CA  1 
ATOM   9167  C C   . LYS D 1 108 ? 47.353  -17.274 113.803 1.00 72.93  ? 127 LYS D C   1 
ATOM   9168  O O   . LYS D 1 108 ? 46.978  -16.401 113.020 1.00 76.44  ? 127 LYS D O   1 
ATOM   9169  C CB  . LYS D 1 108 ? 48.618  -16.035 115.600 1.00 74.08  ? 127 LYS D CB  1 
ATOM   9170  N N   . GLU D 1 109 ? 47.691  -18.498 113.386 1.00 71.06  ? 128 GLU D N   1 
ATOM   9171  C CA  . GLU D 1 109 ? 47.480  -18.878 111.994 1.00 72.67  ? 128 GLU D CA  1 
ATOM   9172  C C   . GLU D 1 109 ? 46.066  -19.392 111.720 1.00 70.69  ? 128 GLU D C   1 
ATOM   9173  O O   . GLU D 1 109 ? 45.482  -19.081 110.682 1.00 73.13  ? 128 GLU D O   1 
ATOM   9174  C CB  . GLU D 1 109 ? 48.421  -19.998 111.531 1.00 71.94  ? 128 GLU D CB  1 
ATOM   9175  C CG  . GLU D 1 109 ? 49.935  -19.880 111.718 1.00 74.28  ? 128 GLU D CG  1 
ATOM   9176  C CD  . GLU D 1 109 ? 50.585  -21.101 111.021 1.00 73.20  ? 128 GLU D CD  1 
ATOM   9177  O OE1 . GLU D 1 109 ? 50.527  -21.096 109.755 1.00 75.68  ? 128 GLU D OE1 1 
ATOM   9178  O OE2 . GLU D 1 109 ? 51.059  -22.069 111.705 1.00 70.15  ? 128 GLU D OE2 1 
ATOM   9179  N N   . TYR D 1 110 ? 45.522  -20.227 112.605 1.00 66.39  ? 129 TYR D N   1 
ATOM   9180  C CA  . TYR D 1 110 ? 44.133  -20.648 112.447 1.00 64.50  ? 129 TYR D CA  1 
ATOM   9181  C C   . TYR D 1 110 ? 43.210  -19.439 112.529 1.00 66.53  ? 129 TYR D C   1 
ATOM   9182  O O   . TYR D 1 110 ? 42.126  -19.433 111.939 1.00 67.08  ? 129 TYR D O   1 
ATOM   9183  C CB  . TYR D 1 110 ? 43.778  -21.720 113.496 1.00 59.78  ? 129 TYR D CB  1 
ATOM   9184  C CG  . TYR D 1 110 ? 42.393  -22.347 113.364 1.00 57.58  ? 129 TYR D CG  1 
ATOM   9185  C CD1 . TYR D 1 110 ? 42.139  -23.361 112.451 1.00 57.07  ? 129 TYR D CD1 1 
ATOM   9186  C CD2 . TYR D 1 110 ? 41.354  -21.956 114.187 1.00 56.20  ? 129 TYR D CD2 1 
ATOM   9187  C CE1 . TYR D 1 110 ? 40.861  -23.946 112.355 1.00 55.31  ? 129 TYR D CE1 1 
ATOM   9188  C CE2 . TYR D 1 110 ? 40.093  -22.512 114.088 1.00 54.68  ? 129 TYR D CE2 1 
ATOM   9189  C CZ  . TYR D 1 110 ? 39.839  -23.500 113.182 1.00 54.25  ? 129 TYR D CZ  1 
ATOM   9190  O OH  . TYR D 1 110 ? 38.557  -24.048 113.142 1.00 52.99  ? 129 TYR D OH  1 
ATOM   9191  N N   . ALA D 1 111 ? 43.633  -18.398 113.233 1.00 67.73  ? 130 ALA D N   1 
ATOM   9192  C CA  . ALA D 1 111 ? 42.801  -17.212 113.357 1.00 69.99  ? 130 ALA D CA  1 
ATOM   9193  C C   . ALA D 1 111 ? 42.640  -16.467 112.033 1.00 74.40  ? 130 ALA D C   1 
ATOM   9194  O O   . ALA D 1 111 ? 41.632  -15.773 111.853 1.00 76.13  ? 130 ALA D O   1 
ATOM   9195  C CB  . ALA D 1 111 ? 43.391  -16.310 114.445 1.00 70.79  ? 130 ALA D CB  1 
ATOM   9196  N N   . LYS D 1 112 ? 43.582  -16.610 111.103 1.00 76.42  ? 131 LYS D N   1 
ATOM   9197  C CA  . LYS D 1 112 ? 43.542  -15.890 109.838 1.00 81.04  ? 131 LYS D CA  1 
ATOM   9198  C C   . LYS D 1 112 ? 42.858  -16.683 108.724 1.00 80.96  ? 131 LYS D C   1 
ATOM   9199  O O   . LYS D 1 112 ? 42.934  -16.275 107.560 1.00 84.82  ? 131 LYS D O   1 
ATOM   9200  C CB  . LYS D 1 112 ? 44.968  -15.507 109.416 1.00 84.10  ? 131 LYS D CB  1 
ATOM   9201  N N   . HIS D 1 113 ? 42.196  -17.800 109.056 1.00 76.85  ? 132 HIS D N   1 
ATOM   9202  C CA  . HIS D 1 113 ? 41.563  -18.691 108.072 1.00 76.40  ? 132 HIS D CA  1 
ATOM   9203  C C   . HIS D 1 113 ? 40.119  -18.990 108.478 1.00 73.97  ? 132 HIS D C   1 
ATOM   9204  O O   . HIS D 1 113 ? 39.761  -20.132 108.769 1.00 70.43  ? 132 HIS D O   1 
ATOM   9205  C CB  . HIS D 1 113 ? 42.364  -19.984 107.921 1.00 74.13  ? 132 HIS D CB  1 
ATOM   9206  C CG  . HIS D 1 113 ? 43.723  -19.793 107.310 1.00 77.07  ? 132 HIS D CG  1 
ATOM   9207  N ND1 . HIS D 1 113 ? 44.828  -19.431 108.053 1.00 77.68  ? 132 HIS D ND1 1 
ATOM   9208  C CD2 . HIS D 1 113 ? 44.156  -19.907 106.030 1.00 79.87  ? 132 HIS D CD2 1 
ATOM   9209  C CE1 . HIS D 1 113 ? 45.882  -19.335 107.262 1.00 80.70  ? 132 HIS D CE1 1 
ATOM   9210  N NE2 . HIS D 1 113 ? 45.502  -19.623 106.030 1.00 82.08  ? 132 HIS D NE2 1 
ATOM   9211  N N   . PRO D 1 114 ? 39.255  -17.965 108.495 1.00 76.02  ? 133 PRO D N   1 
ATOM   9212  C CA  . PRO D 1 114 ? 37.851  -18.171 108.931 1.00 74.12  ? 133 PRO D CA  1 
ATOM   9213  C C   . PRO D 1 114 ? 37.044  -19.109 108.039 1.00 73.75  ? 133 PRO D C   1 
ATOM   9214  O O   . PRO D 1 114 ? 35.973  -19.585 108.449 1.00 71.64  ? 133 PRO D O   1 
ATOM   9215  C CB  . PRO D 1 114 ? 37.271  -16.743 108.893 1.00 77.65  ? 133 PRO D CB  1 
ATOM   9216  C CG  . PRO D 1 114 ? 38.164  -15.992 107.936 1.00 82.10  ? 133 PRO D CG  1 
ATOM   9217  C CD  . PRO D 1 114 ? 39.535  -16.548 108.172 1.00 80.48  ? 133 PRO D CD  1 
ATOM   9218  N N   . GLN D 1 115 ? 37.513  -19.354 106.811 1.00 76.28  ? 134 GLN D N   1 
ATOM   9219  C CA  . GLN D 1 115 ? 36.926  -20.280 105.856 1.00 76.36  ? 134 GLN D CA  1 
ATOM   9220  C C   . GLN D 1 115 ? 37.080  -21.736 106.262 1.00 71.84  ? 134 GLN D C   1 
ATOM   9221  O O   . GLN D 1 115 ? 36.418  -22.585 105.656 1.00 71.00  ? 134 GLN D O   1 
ATOM   9222  C CB  . GLN D 1 115 ? 37.569  -20.053 104.475 1.00 80.54  ? 134 GLN D CB  1 
ATOM   9223  C CG  . GLN D 1 115 ? 39.094  -20.260 104.420 1.00 79.93  ? 134 GLN D CG  1 
ATOM   9224  C CD  . GLN D 1 115 ? 39.876  -18.986 104.727 1.00 82.78  ? 134 GLN D CD  1 
ATOM   9225  O OE1 . GLN D 1 115 ? 39.477  -18.188 105.587 1.00 82.74  ? 134 GLN D OE1 1 
ATOM   9226  N NE2 . GLN D 1 115 ? 40.979  -18.779 104.017 1.00 85.68  ? 134 GLN D NE2 1 
ATOM   9227  N N   . TRP D 1 116 ? 37.928  -22.042 107.255 1.00 69.15  ? 135 TRP D N   1 
ATOM   9228  C CA  . TRP D 1 116 ? 38.040  -23.389 107.774 1.00 65.00  ? 135 TRP D CA  1 
ATOM   9229  C C   . TRP D 1 116 ? 37.134  -23.642 108.965 1.00 61.59  ? 135 TRP D C   1 
ATOM   9230  O O   . TRP D 1 116 ? 36.891  -24.807 109.316 1.00 58.38  ? 135 TRP D O   1 
ATOM   9231  C CB  . TRP D 1 116 ? 39.466  -23.674 108.236 1.00 63.78  ? 135 TRP D CB  1 
ATOM   9232  C CG  . TRP D 1 116 ? 40.495  -23.616 107.202 1.00 66.85  ? 135 TRP D CG  1 
ATOM   9233  C CD1 . TRP D 1 116 ? 40.320  -23.557 105.871 1.00 70.07  ? 135 TRP D CD1 1 
ATOM   9234  C CD2 . TRP D 1 116 ? 41.888  -23.631 107.432 1.00 67.06  ? 135 TRP D CD2 1 
ATOM   9235  N NE1 . TRP D 1 116 ? 41.531  -23.542 105.235 1.00 72.43  ? 135 TRP D NE1 1 
ATOM   9236  C CE2 . TRP D 1 116 ? 42.515  -23.576 106.178 1.00 70.64  ? 135 TRP D CE2 1 
ATOM   9237  C CE3 . TRP D 1 116 ? 42.671  -23.706 108.585 1.00 64.78  ? 135 TRP D CE3 1 
ATOM   9238  C CZ2 . TRP D 1 116 ? 43.884  -23.580 106.035 1.00 72.08  ? 135 TRP D CZ2 1 
ATOM   9239  C CZ3 . TRP D 1 116 ? 44.028  -23.698 108.447 1.00 66.21  ? 135 TRP D CZ3 1 
ATOM   9240  C CH2 . TRP D 1 116 ? 44.627  -23.632 107.177 1.00 69.86  ? 135 TRP D CH2 1 
ATOM   9241  N N   . TRP D 1 117 ? 36.644  -22.590 109.604 1.00 56.54  ? 136 TRP D N   1 
ATOM   9242  C CA  . TRP D 1 117 ? 36.110  -22.727 110.952 1.00 55.59  ? 136 TRP D CA  1 
ATOM   9243  C C   . TRP D 1 117 ? 34.827  -23.540 110.959 1.00 55.95  ? 136 TRP D C   1 
ATOM   9244  O O   . TRP D 1 117 ? 33.896  -23.257 110.210 1.00 57.48  ? 136 TRP D O   1 
ATOM   9245  C CB  . TRP D 1 117 ? 35.835  -21.358 111.570 1.00 57.18  ? 136 TRP D CB  1 
ATOM   9246  C CG  . TRP D 1 117 ? 37.041  -20.510 111.769 1.00 57.96  ? 136 TRP D CG  1 
ATOM   9247  C CD1 . TRP D 1 117 ? 38.346  -20.891 111.661 1.00 57.19  ? 136 TRP D CD1 1 
ATOM   9248  C CD2 . TRP D 1 117 ? 37.054  -19.118 112.134 1.00 60.94  ? 136 TRP D CD2 1 
ATOM   9249  N NE1 . TRP D 1 117 ? 39.173  -19.805 111.919 1.00 59.60  ? 136 TRP D NE1 1 
ATOM   9250  C CE2 . TRP D 1 117 ? 38.400  -18.722 112.233 1.00 61.94  ? 136 TRP D CE2 1 
ATOM   9251  C CE3 . TRP D 1 117 ? 36.056  -18.181 112.396 1.00 63.39  ? 136 TRP D CE3 1 
ATOM   9252  C CZ2 . TRP D 1 117 ? 38.774  -17.427 112.554 1.00 65.32  ? 136 TRP D CZ2 1 
ATOM   9253  C CZ3 . TRP D 1 117 ? 36.425  -16.882 112.714 1.00 66.67  ? 136 TRP D CZ3 1 
ATOM   9254  C CH2 . TRP D 1 117 ? 37.777  -16.510 112.786 1.00 67.75  ? 136 TRP D CH2 1 
ATOM   9255  N N   . LEU D 1 118 ? 34.777  -24.547 111.824 1.00 53.50  ? 137 LEU D N   1 
ATOM   9256  C CA  . LEU D 1 118 ? 33.565  -25.341 111.951 1.00 53.99  ? 137 LEU D CA  1 
ATOM   9257  C C   . LEU D 1 118 ? 32.390  -24.467 112.361 1.00 55.37  ? 137 LEU D C   1 
ATOM   9258  O O   . LEU D 1 118 ? 32.514  -23.578 113.216 1.00 55.46  ? 137 LEU D O   1 
ATOM   9259  C CB  . LEU D 1 118 ? 33.764  -26.439 112.981 1.00 52.96  ? 137 LEU D CB  1 
ATOM   9260  C CG  . LEU D 1 118 ? 32.651  -27.479 113.106 1.00 53.55  ? 137 LEU D CG  1 
ATOM   9261  C CD1 . LEU D 1 118 ? 32.330  -28.098 111.781 1.00 54.17  ? 137 LEU D CD1 1 
ATOM   9262  C CD2 . LEU D 1 118 ? 33.093  -28.539 114.096 1.00 52.97  ? 137 LEU D CD2 1 
ATOM   9263  N N   . ARG D 1 119 ? 31.238  -24.712 111.706 1.00 54.63  ? 138 ARG D N   1 
ATOM   9264  C CA  . ARG D 1 119 ? 29.988  -24.033 112.016 1.00 56.00  ? 138 ARG D CA  1 
ATOM   9265  C C   . ARG D 1 119 ? 28.886  -25.046 112.277 1.00 56.22  ? 138 ARG D C   1 
ATOM   9266  O O   . ARG D 1 119 ? 28.833  -26.126 111.668 1.00 56.36  ? 138 ARG D O   1 
ATOM   9267  C CB  . ARG D 1 119 ? 29.518  -23.115 110.897 1.00 57.82  ? 138 ARG D CB  1 
ATOM   9268  C CG  . ARG D 1 119 ? 30.345  -21.873 110.763 1.00 58.39  ? 138 ARG D CG  1 
ATOM   9269  C CD  . ARG D 1 119 ? 29.925  -21.106 109.566 1.00 63.61  ? 138 ARG D CD  1 
ATOM   9270  N NE  . ARG D 1 119 ? 30.937  -20.136 109.196 1.00 66.06  ? 138 ARG D NE  1 
ATOM   9271  C CZ  . ARG D 1 119 ? 30.932  -18.860 109.579 1.00 68.37  ? 138 ARG D CZ  1 
ATOM   9272  N NH1 . ARG D 1 119 ? 30.061  -18.402 110.468 1.00 68.86  ? 138 ARG D NH1 1 
ATOM   9273  N NH2 . ARG D 1 119 ? 31.825  -18.021 109.059 1.00 70.86  ? 138 ARG D NH2 1 
ATOM   9274  N N   . THR D 1 120 ? 28.000  -24.676 113.188 1.00 55.54  ? 139 THR D N   1 
ATOM   9275  C CA  . THR D 1 120 ? 26.870  -25.525 113.492 1.00 56.03  ? 139 THR D CA  1 
ATOM   9276  C C   . THR D 1 120 ? 25.835  -25.433 112.370 1.00 57.31  ? 139 THR D C   1 
ATOM   9277  O O   . THR D 1 120 ? 25.941  -24.633 111.436 1.00 58.08  ? 139 THR D O   1 
ATOM   9278  C CB  . THR D 1 120 ? 26.256  -25.130 114.833 1.00 56.86  ? 139 THR D CB  1 
ATOM   9279  O OG1 . THR D 1 120 ? 25.664  -23.830 114.721 1.00 58.20  ? 139 THR D OG1 1 
ATOM   9280  C CG2 . THR D 1 120 ? 27.322  -25.105 115.914 1.00 56.11  ? 139 THR D CG2 1 
ATOM   9281  N N   . THR D 1 121 ? 24.820  -26.278 112.471 1.00 54.13  ? 140 THR D N   1 
ATOM   9282  C CA  . THR D 1 121 ? 23.768  -26.262 111.462 1.00 57.27  ? 140 THR D CA  1 
ATOM   9283  C C   . THR D 1 121 ? 23.024  -24.932 111.397 1.00 60.97  ? 140 THR D C   1 
ATOM   9284  O O   . THR D 1 121 ? 22.260  -24.718 110.443 1.00 64.07  ? 140 THR D O   1 
ATOM   9285  C CB  . THR D 1 121 ? 22.799  -27.400 111.762 1.00 57.18  ? 140 THR D CB  1 
ATOM   9286  O OG1 . THR D 1 121 ? 22.286  -27.216 113.089 1.00 57.42  ? 140 THR D OG1 1 
ATOM   9287  C CG2 . THR D 1 121 ? 23.522  -28.757 111.648 1.00 55.69  ? 140 THR D CG2 1 
ATOM   9288  N N   . THR D 1 122 ? 23.214  -24.041 112.374 1.00 58.83  ? 141 THR D N   1 
ATOM   9289  C CA  . THR D 1 122 ? 22.576  -22.732 112.337 1.00 64.97  ? 141 THR D CA  1 
ATOM   9290  C C   . THR D 1 122 ? 23.458  -21.662 111.718 1.00 67.79  ? 141 THR D C   1 
ATOM   9291  O O   . THR D 1 122 ? 23.047  -20.504 111.656 1.00 72.33  ? 141 THR D O   1 
ATOM   9292  C CB  . THR D 1 122 ? 22.182  -22.283 113.744 1.00 64.71  ? 141 THR D CB  1 
ATOM   9293  O OG1 . THR D 1 122 ? 23.360  -22.034 114.518 1.00 61.13  ? 141 THR D OG1 1 
ATOM   9294  C CG2 . THR D 1 122 ? 21.348  -23.341 114.418 1.00 62.30  ? 141 THR D CG2 1 
ATOM   9295  N N   . GLY D 1 123 ? 24.651  -22.022 111.263 1.00 64.30  ? 142 GLY D N   1 
ATOM   9296  C CA  . GLY D 1 123 ? 25.596  -21.051 110.769 1.00 67.21  ? 142 GLY D CA  1 
ATOM   9297  C C   . GLY D 1 123 ? 26.453  -20.440 111.841 1.00 65.87  ? 142 GLY D C   1 
ATOM   9298  O O   . GLY D 1 123 ? 27.327  -19.619 111.527 1.00 67.31  ? 142 GLY D O   1 
ATOM   9299  N N   . GLU D 1 124 ? 26.229  -20.819 113.093 1.00 63.32  ? 143 GLU D N   1 
ATOM   9300  C CA  . GLU D 1 124 ? 26.958  -20.275 114.218 1.00 61.80  ? 143 GLU D CA  1 
ATOM   9301  C C   . GLU D 1 124 ? 28.292  -20.970 114.370 1.00 58.59  ? 143 GLU D C   1 
ATOM   9302  O O   . GLU D 1 124 ? 28.416  -22.173 114.140 1.00 58.05  ? 143 GLU D O   1 
ATOM   9303  C CB  . GLU D 1 124 ? 26.155  -20.447 115.498 1.00 61.67  ? 143 GLU D CB  1 
ATOM   9304  C CG  . GLU D 1 124 ? 26.055  -19.159 116.273 1.00 62.57  ? 143 GLU D CG  1 
ATOM   9305  C CD  . GLU D 1 124 ? 25.747  -19.399 117.737 1.00 64.63  ? 143 GLU D CD  1 
ATOM   9306  O OE1 . GLU D 1 124 ? 24.707  -20.067 117.963 1.00 65.11  ? 143 GLU D OE1 1 
ATOM   9307  O OE2 . GLU D 1 124 ? 26.524  -18.943 118.627 1.00 66.65  ? 143 GLU D OE2 1 
ATOM   9308  N N   . LEU D 1 125 ? 29.295  -20.212 114.793 1.00 57.06  ? 144 LEU D N   1 
ATOM   9309  C CA  . LEU D 1 125 ? 30.602  -20.815 115.003 1.00 53.66  ? 144 LEU D CA  1 
ATOM   9310  C C   . LEU D 1 125 ? 30.515  -21.912 116.062 1.00 52.48  ? 144 LEU D C   1 
ATOM   9311  O O   . LEU D 1 125 ? 29.924  -21.721 117.124 1.00 53.03  ? 144 LEU D O   1 
ATOM   9312  C CB  . LEU D 1 125 ? 31.615  -19.766 115.421 1.00 55.36  ? 144 LEU D CB  1 
ATOM   9313  C CG  . LEU D 1 125 ? 32.110  -18.927 114.258 1.00 60.60  ? 144 LEU D CG  1 
ATOM   9314  C CD1 . LEU D 1 125 ? 33.076  -17.852 114.706 1.00 63.06  ? 144 LEU D CD1 1 
ATOM   9315  C CD2 . LEU D 1 125 ? 32.735  -19.799 113.178 1.00 58.56  ? 144 LEU D CD2 1 
ATOM   9316  N N   . ASP D 1 126 ? 31.108  -23.056 115.781 1.00 53.21  ? 145 ASP D N   1 
ATOM   9317  C CA  . ASP D 1 126 ? 31.142  -24.117 116.775 1.00 52.39  ? 145 ASP D CA  1 
ATOM   9318  C C   . ASP D 1 126 ? 32.249  -23.788 117.762 1.00 51.88  ? 145 ASP D C   1 
ATOM   9319  O O   . ASP D 1 126 ? 33.429  -23.845 117.415 1.00 50.94  ? 145 ASP D O   1 
ATOM   9320  C CB  . ASP D 1 126 ? 31.369  -25.477 116.121 1.00 51.89  ? 145 ASP D CB  1 
ATOM   9321  C CG  . ASP D 1 126 ? 31.167  -26.617 117.096 1.00 51.97  ? 145 ASP D CG  1 
ATOM   9322  O OD1 . ASP D 1 126 ? 31.321  -26.381 118.315 1.00 51.67  ? 145 ASP D OD1 1 
ATOM   9323  O OD2 . ASP D 1 126 ? 30.849  -27.745 116.653 1.00 52.34  ? 145 ASP D OD2 1 
ATOM   9324  N N   . ARG D 1 127 ? 31.881  -23.429 118.983 1.00 54.15  ? 146 ARG D N   1 
ATOM   9325  C CA  . ARG D 1 127 ? 32.868  -23.139 120.016 1.00 54.01  ? 146 ARG D CA  1 
ATOM   9326  C C   . ARG D 1 127 ? 32.514  -23.911 121.279 1.00 53.96  ? 146 ARG D C   1 
ATOM   9327  O O   . ARG D 1 127 ? 31.360  -23.877 121.724 1.00 55.07  ? 146 ARG D O   1 
ATOM   9328  C CB  . ARG D 1 127 ? 32.949  -21.638 120.321 1.00 55.17  ? 146 ARG D CB  1 
ATOM   9329  N N   . LYS D 1 128 ? 33.513  -24.597 121.844 1.00 55.49  ? 147 LYS D N   1 
ATOM   9330  C CA  . LYS D 1 128 ? 33.374  -25.255 123.138 1.00 55.43  ? 147 LYS D CA  1 
ATOM   9331  C C   . LYS D 1 128 ? 33.318  -24.238 124.267 1.00 56.74  ? 147 LYS D C   1 
ATOM   9332  O O   . LYS D 1 128 ? 34.172  -23.343 124.360 1.00 56.85  ? 147 LYS D O   1 
ATOM   9333  C CB  . LYS D 1 128 ? 34.556  -26.198 123.378 1.00 54.59  ? 147 LYS D CB  1 
ATOM   9334  C CG  . LYS D 1 128 ? 34.394  -27.214 124.507 1.00 55.88  ? 147 LYS D CG  1 
ATOM   9335  C CD  . LYS D 1 128 ? 35.662  -28.038 124.691 1.00 55.29  ? 147 LYS D CD  1 
ATOM   9336  C CE  . LYS D 1 128 ? 35.636  -28.822 125.995 1.00 54.97  ? 147 LYS D CE  1 
ATOM   9337  N NZ  . LYS D 1 128 ? 36.841  -29.703 126.138 1.00 54.08  ? 147 LYS D NZ  1 
ATOM   9338  N N   . LYS D 1 129 ? 32.318  -24.378 125.140 1.00 59.28  ? 148 LYS D N   1 
ATOM   9339  C CA  . LYS D 1 129 ? 32.136  -23.455 126.274 1.00 61.30  ? 148 LYS D CA  1 
ATOM   9340  C C   . LYS D 1 129 ? 32.032  -21.983 125.834 1.00 64.11  ? 148 LYS D C   1 
ATOM   9341  O O   . LYS D 1 129 ? 32.198  -21.072 126.662 1.00 68.50  ? 148 LYS D O   1 
ATOM   9342  C CB  . LYS D 1 129 ? 33.269  -23.607 127.307 1.00 61.31  ? 148 LYS D CB  1 
ATOM   9343  N N   . GLY D 1 130 ? 31.732  -21.739 124.554 1.00 63.55  ? 149 GLY D N   1 
ATOM   9344  C CA  . GLY D 1 130 ? 31.650  -20.373 124.048 1.00 65.72  ? 149 GLY D CA  1 
ATOM   9345  C C   . GLY D 1 130 ? 32.956  -19.619 124.144 1.00 66.23  ? 149 GLY D C   1 
ATOM   9346  O O   . GLY D 1 130 ? 32.949  -18.389 124.247 1.00 69.19  ? 149 GLY D O   1 
ATOM   9347  N N   . GLN D 1 131 ? 34.084  -20.329 124.152 1.00 66.83  ? 150 GLN D N   1 
ATOM   9348  C CA  . GLN D 1 131 ? 35.379  -19.656 124.192 1.00 67.03  ? 150 GLN D CA  1 
ATOM   9349  C C   . GLN D 1 131 ? 36.313  -20.328 123.193 1.00 65.03  ? 150 GLN D C   1 
ATOM   9350  O O   . GLN D 1 131 ? 36.973  -19.639 122.408 1.00 64.11  ? 150 GLN D O   1 
ATOM   9351  C CB  . GLN D 1 131 ? 35.958  -19.656 125.611 1.00 67.10  ? 150 GLN D CB  1 
ATOM   9352  N N   . LEU D 1 132 ? 36.338  -21.655 123.170 1.00 59.11  ? 151 LEU D N   1 
ATOM   9353  C CA  . LEU D 1 132 ? 37.271  -22.406 122.342 1.00 57.30  ? 151 LEU D CA  1 
ATOM   9354  C C   . LEU D 1 132 ? 36.625  -22.906 121.051 1.00 56.28  ? 151 LEU D C   1 
ATOM   9355  O O   . LEU D 1 132 ? 35.525  -23.471 121.070 1.00 56.43  ? 151 LEU D O   1 
ATOM   9356  C CB  . LEU D 1 132 ? 37.799  -23.632 123.094 1.00 56.67  ? 151 LEU D CB  1 
ATOM   9357  C CG  . LEU D 1 132 ? 39.178  -23.626 123.735 1.00 57.16  ? 151 LEU D CG  1 
ATOM   9358  C CD1 . LEU D 1 132 ? 39.471  -25.035 124.211 1.00 56.62  ? 151 LEU D CD1 1 
ATOM   9359  C CD2 . LEU D 1 132 ? 40.217  -23.132 122.768 1.00 57.32  ? 151 LEU D CD2 1 
ATOM   9360  N N   . MET D 1 133 ? 37.348  -22.783 119.945 1.00 55.75  ? 152 MET D N   1 
ATOM   9361  C CA  . MET D 1 133 ? 36.826  -23.171 118.640 1.00 55.18  ? 152 MET D CA  1 
ATOM   9362  C C   . MET D 1 133 ? 37.168  -24.622 118.366 1.00 53.98  ? 152 MET D C   1 
ATOM   9363  O O   . MET D 1 133 ? 38.292  -25.059 118.620 1.00 53.39  ? 152 MET D O   1 
ATOM   9364  C CB  . MET D 1 133 ? 37.432  -22.277 117.552 1.00 56.06  ? 152 MET D CB  1 
ATOM   9365  C CG  . MET D 1 133 ? 36.675  -20.995 117.315 1.00 58.34  ? 152 MET D CG  1 
ATOM   9366  S SD  . MET D 1 133 ? 37.094  -20.043 115.790 1.00 58.58  ? 152 MET D SD  1 
ATOM   9367  C CE  . MET D 1 133 ? 38.917  -20.019 115.824 1.00 58.60  ? 152 MET D CE  1 
ATOM   9368  N N   . ARG D 1 134 ? 36.192  -25.368 117.838 1.00 49.34  ? 153 ARG D N   1 
ATOM   9369  C CA  . ARG D 1 134 ? 36.374  -26.782 117.516 1.00 48.25  ? 153 ARG D CA  1 
ATOM   9370  C C   . ARG D 1 134 ? 36.598  -26.927 116.022 1.00 47.79  ? 153 ARG D C   1 
ATOM   9371  O O   . ARG D 1 134 ? 35.866  -26.340 115.225 1.00 48.92  ? 153 ARG D O   1 
ATOM   9372  C CB  . ARG D 1 134 ? 35.167  -27.613 117.942 1.00 49.08  ? 153 ARG D CB  1 
ATOM   9373  C CG  . ARG D 1 134 ? 34.715  -27.325 119.344 1.00 49.52  ? 153 ARG D CG  1 
ATOM   9374  C CD  . ARG D 1 134 ? 33.903  -28.434 119.938 1.00 49.73  ? 153 ARG D CD  1 
ATOM   9375  N NE  . ARG D 1 134 ? 32.711  -28.743 119.176 1.00 50.56  ? 153 ARG D NE  1 
ATOM   9376  C CZ  . ARG D 1 134 ? 31.918  -29.774 119.438 1.00 50.99  ? 153 ARG D CZ  1 
ATOM   9377  N NH1 . ARG D 1 134 ? 32.212  -30.640 120.392 1.00 50.08  ? 153 ARG D NH1 1 
ATOM   9378  N NH2 . ARG D 1 134 ? 30.803  -29.940 118.734 1.00 52.08  ? 153 ARG D NH2 1 
ATOM   9379  N N   . TYR D 1 135 ? 37.586  -27.710 115.646 1.00 50.09  ? 154 TYR D N   1 
ATOM   9380  C CA  . TYR D 1 135 ? 37.993  -27.809 114.259 1.00 49.66  ? 154 TYR D CA  1 
ATOM   9381  C C   . TYR D 1 135 ? 37.031  -28.655 113.431 1.00 49.80  ? 154 TYR D C   1 
ATOM   9382  O O   . TYR D 1 135 ? 36.436  -29.609 113.926 1.00 50.13  ? 154 TYR D O   1 
ATOM   9383  C CB  . TYR D 1 135 ? 39.369  -28.461 114.134 1.00 47.93  ? 154 TYR D CB  1 
ATOM   9384  C CG  . TYR D 1 135 ? 40.535  -27.810 114.820 1.00 47.81  ? 154 TYR D CG  1 
ATOM   9385  C CD1 . TYR D 1 135 ? 40.797  -26.428 114.687 1.00 49.08  ? 154 TYR D CD1 1 
ATOM   9386  C CD2 . TYR D 1 135 ? 41.414  -28.591 115.581 1.00 46.84  ? 154 TYR D CD2 1 
ATOM   9387  C CE1 . TYR D 1 135 ? 41.905  -25.842 115.308 1.00 49.42  ? 154 TYR D CE1 1 
ATOM   9388  C CE2 . TYR D 1 135 ? 42.510  -28.027 116.198 1.00 46.96  ? 154 TYR D CE2 1 
ATOM   9389  C CZ  . TYR D 1 135 ? 42.747  -26.655 116.056 1.00 48.21  ? 154 TYR D CZ  1 
ATOM   9390  O OH  . TYR D 1 135 ? 43.834  -26.169 116.682 1.00 49.14  ? 154 TYR D OH  1 
ATOM   9391  N N   . ASP D 1 136 ? 36.933  -28.325 112.131 1.00 51.44  ? 155 ASP D N   1 
ATOM   9392  C CA  . ASP D 1 136 ? 36.278  -29.163 111.119 1.00 51.64  ? 155 ASP D CA  1 
ATOM   9393  C C   . ASP D 1 136 ? 37.329  -30.051 110.459 1.00 50.09  ? 155 ASP D C   1 
ATOM   9394  O O   . ASP D 1 136 ? 38.006  -29.643 109.506 1.00 50.65  ? 155 ASP D O   1 
ATOM   9395  C CB  . ASP D 1 136 ? 35.568  -28.307 110.084 1.00 53.38  ? 155 ASP D CB  1 
ATOM   9396  C CG  . ASP D 1 136 ? 34.848  -29.124 109.047 1.00 54.48  ? 155 ASP D CG  1 
ATOM   9397  O OD1 . ASP D 1 136 ? 35.007  -30.348 109.000 1.00 53.70  ? 155 ASP D OD1 1 
ATOM   9398  O OD2 . ASP D 1 136 ? 34.099  -28.545 108.257 1.00 56.53  ? 155 ASP D OD2 1 
ATOM   9399  N N   . LEU D 1 137 ? 37.439  -31.293 110.950 1.00 53.58  ? 156 LEU D N   1 
ATOM   9400  C CA  . LEU D 1 137 ? 38.411  -32.239 110.418 1.00 52.10  ? 156 LEU D CA  1 
ATOM   9401  C C   . LEU D 1 137 ? 38.061  -32.739 109.012 1.00 52.91  ? 156 LEU D C   1 
ATOM   9402  O O   . LEU D 1 137 ? 38.891  -33.419 108.386 1.00 52.14  ? 156 LEU D O   1 
ATOM   9403  C CB  . LEU D 1 137 ? 38.551  -33.418 111.375 1.00 51.40  ? 156 LEU D CB  1 
ATOM   9404  C CG  . LEU D 1 137 ? 38.704  -33.136 112.863 1.00 51.68  ? 156 LEU D CG  1 
ATOM   9405  C CD1 . LEU D 1 137 ? 38.909  -34.431 113.566 1.00 50.66  ? 156 LEU D CD1 1 
ATOM   9406  C CD2 . LEU D 1 137 ? 39.863  -32.301 113.143 1.00 51.43  ? 156 LEU D CD2 1 
ATOM   9407  N N   . SER D 1 138 ? 36.875  -32.415 108.489 1.00 52.09  ? 157 SER D N   1 
ATOM   9408  C CA  . SER D 1 138 ? 36.565  -32.763 107.107 1.00 53.13  ? 157 SER D CA  1 
ATOM   9409  C C   . SER D 1 138 ? 37.198  -31.804 106.107 1.00 53.73  ? 157 SER D C   1 
ATOM   9410  O O   . SER D 1 138 ? 37.201  -32.096 104.903 1.00 55.05  ? 157 SER D O   1 
ATOM   9411  C CB  . SER D 1 138 ? 35.053  -32.791 106.909 1.00 55.52  ? 157 SER D CB  1 
ATOM   9412  O OG  . SER D 1 138 ? 34.555  -31.480 106.795 1.00 56.79  ? 157 SER D OG  1 
ATOM   9413  N N   . ASN D 1 139 ? 37.742  -30.681 106.587 1.00 56.55  ? 158 ASN D N   1 
ATOM   9414  C CA  . ASN D 1 139 ? 38.403  -29.691 105.737 1.00 57.50  ? 158 ASN D CA  1 
ATOM   9415  C C   . ASN D 1 139 ? 39.854  -30.088 105.471 1.00 57.11  ? 158 ASN D C   1 
ATOM   9416  O O   . ASN D 1 139 ? 40.677  -30.131 106.390 1.00 55.50  ? 158 ASN D O   1 
ATOM   9417  C CB  . ASN D 1 139 ? 38.334  -28.316 106.411 1.00 58.26  ? 158 ASN D CB  1 
ATOM   9418  C CG  . ASN D 1 139 ? 38.974  -27.207 105.582 1.00 61.00  ? 158 ASN D CG  1 
ATOM   9419  O OD1 . ASN D 1 139 ? 40.134  -27.295 105.158 1.00 61.70  ? 158 ASN D OD1 1 
ATOM   9420  N ND2 . ASN D 1 139 ? 38.219  -26.127 105.378 1.00 63.52  ? 158 ASN D ND2 1 
ATOM   9421  N N   . ALA D 1 140 ? 40.169  -30.343 104.200 1.00 57.95  ? 159 ALA D N   1 
ATOM   9422  C CA  . ALA D 1 140 ? 41.508  -30.777 103.828 1.00 57.87  ? 159 ALA D CA  1 
ATOM   9423  C C   . ALA D 1 140 ? 42.544  -29.668 104.012 1.00 59.28  ? 159 ALA D C   1 
ATOM   9424  O O   . ALA D 1 140 ? 43.649  -29.921 104.512 1.00 58.67  ? 159 ALA D O   1 
ATOM   9425  C CB  . ALA D 1 140 ? 41.494  -31.266 102.384 1.00 61.07  ? 159 ALA D CB  1 
ATOM   9426  N N   . GLU D 1 141 ? 42.225  -28.437 103.600 1.00 62.70  ? 160 GLU D N   1 
ATOM   9427  C CA  . GLU D 1 141 ? 43.158  -27.333 103.813 1.00 64.75  ? 160 GLU D CA  1 
ATOM   9428  C C   . GLU D 1 141 ? 43.568  -27.286 105.276 1.00 61.24  ? 160 GLU D C   1 
ATOM   9429  O O   . GLU D 1 141 ? 44.753  -27.157 105.601 1.00 61.30  ? 160 GLU D O   1 
ATOM   9430  C CB  . GLU D 1 141 ? 42.541  -26.006 103.361 1.00 69.11  ? 160 GLU D CB  1 
ATOM   9431  N N   . PHE D 1 142 ? 42.604  -27.464 106.178 1.00 62.13  ? 161 PHE D N   1 
ATOM   9432  C CA  . PHE D 1 142 ? 42.919  -27.451 107.598 1.00 59.74  ? 161 PHE D CA  1 
ATOM   9433  C C   . PHE D 1 142 ? 43.751  -28.669 108.002 1.00 57.46  ? 161 PHE D C   1 
ATOM   9434  O O   . PHE D 1 142 ? 44.741  -28.547 108.738 1.00 57.46  ? 161 PHE D O   1 
ATOM   9435  C CB  . PHE D 1 142 ? 41.625  -27.399 108.403 1.00 58.84  ? 161 PHE D CB  1 
ATOM   9436  C CG  . PHE D 1 142 ? 41.753  -28.023 109.743 1.00 56.84  ? 161 PHE D CG  1 
ATOM   9437  C CD1 . PHE D 1 142 ? 42.361  -27.335 110.773 1.00 57.69  ? 161 PHE D CD1 1 
ATOM   9438  C CD2 . PHE D 1 142 ? 41.303  -29.305 109.968 1.00 55.40  ? 161 PHE D CD2 1 
ATOM   9439  C CE1 . PHE D 1 142 ? 42.498  -27.914 112.023 1.00 56.42  ? 161 PHE D CE1 1 
ATOM   9440  C CE2 . PHE D 1 142 ? 41.437  -29.889 111.214 1.00 54.13  ? 161 PHE D CE2 1 
ATOM   9441  C CZ  . PHE D 1 142 ? 42.043  -29.197 112.239 1.00 54.63  ? 161 PHE D CZ  1 
ATOM   9442  N N   . ARG D 1 143 ? 43.333  -29.863 107.565 1.00 57.49  ? 162 ARG D N   1 
ATOM   9443  C CA  . ARG D 1 143 ? 44.073  -31.080 107.889 1.00 56.16  ? 162 ARG D CA  1 
ATOM   9444  C C   . ARG D 1 143 ? 45.498  -31.020 107.361 1.00 57.23  ? 162 ARG D C   1 
ATOM   9445  O O   . ARG D 1 143 ? 46.402  -31.634 107.933 1.00 56.09  ? 162 ARG D O   1 
ATOM   9446  C CB  . ARG D 1 143 ? 43.389  -32.313 107.299 1.00 55.35  ? 162 ARG D CB  1 
ATOM   9447  C CG  . ARG D 1 143 ? 42.046  -32.665 107.864 1.00 55.01  ? 162 ARG D CG  1 
ATOM   9448  C CD  . ARG D 1 143 ? 41.722  -34.127 107.562 1.00 54.24  ? 162 ARG D CD  1 
ATOM   9449  N NE  . ARG D 1 143 ? 41.826  -34.498 106.147 1.00 55.39  ? 162 ARG D NE  1 
ATOM   9450  C CZ  . ARG D 1 143 ? 40.814  -34.465 105.284 1.00 56.87  ? 162 ARG D CZ  1 
ATOM   9451  N NH1 . ARG D 1 143 ? 39.608  -34.061 105.648 1.00 58.04  ? 162 ARG D NH1 1 
ATOM   9452  N NH2 . ARG D 1 143 ? 41.021  -34.832 104.023 1.00 59.93  ? 162 ARG D NH2 1 
ATOM   9453  N N   . ASN D 1 144 ? 45.716  -30.320 106.247 1.00 57.90  ? 163 ASN D N   1 
ATOM   9454  C CA  . ASN D 1 144 ? 47.082  -30.116 105.779 1.00 60.79  ? 163 ASN D CA  1 
ATOM   9455  C C   . ASN D 1 144 ? 47.833  -29.204 106.738 1.00 61.01  ? 163 ASN D C   1 
ATOM   9456  O O   . ASN D 1 144 ? 48.966  -29.489 107.149 1.00 61.58  ? 163 ASN D O   1 
ATOM   9457  C CB  . ASN D 1 144 ? 47.092  -29.512 104.374 1.00 65.29  ? 163 ASN D CB  1 
ATOM   9458  C CG  . ASN D 1 144 ? 48.320  -29.906 103.589 1.00 69.81  ? 163 ASN D CG  1 
ATOM   9459  O OD1 . ASN D 1 144 ? 48.602  -31.102 103.445 1.00 70.80  ? 163 ASN D OD1 1 
ATOM   9460  N ND2 . ASN D 1 144 ? 49.060  -28.947 103.106 1.00 72.32  ? 163 ASN D ND2 1 
ATOM   9461  N N   . TRP D 1 145 ? 47.211  -28.084 107.088 1.00 61.40  ? 164 TRP D N   1 
ATOM   9462  C CA  . TRP D 1 145 ? 47.862  -27.143 107.980 1.00 61.79  ? 164 TRP D CA  1 
ATOM   9463  C C   . TRP D 1 145 ? 48.169  -27.809 109.306 1.00 58.30  ? 164 TRP D C   1 
ATOM   9464  O O   . TRP D 1 145 ? 49.296  -27.749 109.806 1.00 59.11  ? 164 TRP D O   1 
ATOM   9465  C CB  . TRP D 1 145 ? 46.963  -25.940 108.175 1.00 63.07  ? 164 TRP D CB  1 
ATOM   9466  C CG  . TRP D 1 145 ? 47.356  -25.101 109.284 1.00 63.14  ? 164 TRP D CG  1 
ATOM   9467  C CD1 . TRP D 1 145 ? 48.389  -24.240 109.313 1.00 66.76  ? 164 TRP D CD1 1 
ATOM   9468  C CD2 . TRP D 1 145 ? 46.725  -25.022 110.552 1.00 60.46  ? 164 TRP D CD2 1 
ATOM   9469  N NE1 . TRP D 1 145 ? 48.442  -23.599 110.522 1.00 65.98  ? 164 TRP D NE1 1 
ATOM   9470  C CE2 . TRP D 1 145 ? 47.425  -24.072 111.305 1.00 62.52  ? 164 TRP D CE2 1 
ATOM   9471  C CE3 . TRP D 1 145 ? 45.631  -25.661 111.130 1.00 58.39  ? 164 TRP D CE3 1 
ATOM   9472  C CZ2 . TRP D 1 145 ? 47.074  -23.744 112.610 1.00 61.60  ? 164 TRP D CZ2 1 
ATOM   9473  C CZ3 . TRP D 1 145 ? 45.293  -25.345 112.448 1.00 58.10  ? 164 TRP D CZ3 1 
ATOM   9474  C CH2 . TRP D 1 145 ? 46.013  -24.394 113.163 1.00 59.72  ? 164 TRP D CH2 1 
ATOM   9475  N N   . TRP D 1 146 ? 47.168  -28.472 109.875 1.00 57.98  ? 165 TRP D N   1 
ATOM   9476  C CA  . TRP D 1 146 ? 47.313  -29.053 111.201 1.00 56.58  ? 165 TRP D CA  1 
ATOM   9477  C C   . TRP D 1 146 ? 48.452  -30.063 111.244 1.00 56.16  ? 165 TRP D C   1 
ATOM   9478  O O   . TRP D 1 146 ? 49.190  -30.123 112.229 1.00 56.32  ? 165 TRP D O   1 
ATOM   9479  C CB  . TRP D 1 146 ? 45.984  -29.702 111.609 1.00 55.26  ? 165 TRP D CB  1 
ATOM   9480  C CG  . TRP D 1 146 ? 45.931  -30.161 113.034 1.00 54.10  ? 165 TRP D CG  1 
ATOM   9481  C CD1 . TRP D 1 146 ? 45.479  -29.451 114.111 1.00 54.24  ? 165 TRP D CD1 1 
ATOM   9482  C CD2 . TRP D 1 146 ? 46.337  -31.434 113.531 1.00 52.67  ? 165 TRP D CD2 1 
ATOM   9483  N NE1 . TRP D 1 146 ? 45.591  -30.204 115.247 1.00 53.47  ? 165 TRP D NE1 1 
ATOM   9484  C CE2 . TRP D 1 146 ? 46.114  -31.428 114.922 1.00 52.19  ? 165 TRP D CE2 1 
ATOM   9485  C CE3 . TRP D 1 146 ? 46.871  -32.582 112.937 1.00 52.23  ? 165 TRP D CE3 1 
ATOM   9486  C CZ2 . TRP D 1 146 ? 46.421  -32.512 115.728 1.00 51.45  ? 165 TRP D CZ2 1 
ATOM   9487  C CZ3 . TRP D 1 146 ? 47.167  -33.655 113.734 1.00 50.98  ? 165 TRP D CZ3 1 
ATOM   9488  C CH2 . TRP D 1 146 ? 46.946  -33.613 115.117 1.00 50.57  ? 165 TRP D CH2 1 
ATOM   9489  N N   . THR D 1 147 ? 48.612  -30.862 110.189 1.00 56.79  ? 166 THR D N   1 
ATOM   9490  C CA  . THR D 1 147 ? 49.674  -31.861 110.156 1.00 56.99  ? 166 THR D CA  1 
ATOM   9491  C C   . THR D 1 147 ? 51.039  -31.222 109.904 1.00 59.52  ? 166 THR D C   1 
ATOM   9492  O O   . THR D 1 147 ? 52.060  -31.721 110.391 1.00 60.06  ? 166 THR D O   1 
ATOM   9493  C CB  . THR D 1 147 ? 49.348  -32.921 109.097 1.00 57.16  ? 166 THR D CB  1 
ATOM   9494  O OG1 . THR D 1 147 ? 49.132  -32.279 107.832 1.00 59.66  ? 166 THR D OG1 1 
ATOM   9495  C CG2 . THR D 1 147 ? 48.089  -33.697 109.485 1.00 55.10  ? 166 THR D CG2 1 
ATOM   9496  N N   . ASN D 1 148 ? 51.067  -30.106 109.181 1.00 56.62  ? 167 ASN D N   1 
ATOM   9497  C CA  . ASN D 1 148 ? 52.305  -29.333 109.033 1.00 60.71  ? 167 ASN D CA  1 
ATOM   9498  C C   . ASN D 1 148 ? 52.776  -28.757 110.365 1.00 59.92  ? 167 ASN D C   1 
ATOM   9499  O O   . ASN D 1 148 ? 53.978  -28.565 110.579 1.00 62.31  ? 167 ASN D O   1 
ATOM   9500  C CB  . ASN D 1 148 ? 52.104  -28.204 108.016 1.00 65.12  ? 167 ASN D CB  1 
ATOM   9501  C CG  . ASN D 1 148 ? 52.390  -28.647 106.588 1.00 68.70  ? 167 ASN D CG  1 
ATOM   9502  O OD1 . ASN D 1 148 ? 52.975  -29.697 106.376 1.00 68.29  ? 167 ASN D OD1 1 
ATOM   9503  N ND2 . ASN D 1 148 ? 51.988  -27.847 105.609 1.00 72.62  ? 167 ASN D ND2 1 
ATOM   9504  N N   . VAL D 1 149 ? 51.852  -28.453 111.262 1.00 59.70  ? 168 VAL D N   1 
ATOM   9505  C CA  . VAL D 1 149 ? 52.240  -27.953 112.569 1.00 59.66  ? 168 VAL D CA  1 
ATOM   9506  C C   . VAL D 1 149 ? 52.928  -29.060 113.358 1.00 58.69  ? 168 VAL D C   1 
ATOM   9507  O O   . VAL D 1 149 ? 54.003  -28.870 113.941 1.00 60.36  ? 168 VAL D O   1 
ATOM   9508  C CB  . VAL D 1 149 ? 51.009  -27.400 113.307 1.00 58.48  ? 168 VAL D CB  1 
ATOM   9509  C CG1 . VAL D 1 149 ? 51.374  -27.048 114.723 1.00 59.11  ? 168 VAL D CG1 1 
ATOM   9510  C CG2 . VAL D 1 149 ? 50.431  -26.184 112.550 1.00 59.69  ? 168 VAL D CG2 1 
ATOM   9511  N N   . ALA D 1 150 ? 52.328  -30.250 113.343 1.00 58.64  ? 169 ALA D N   1 
ATOM   9512  C CA  . ALA D 1 150 ? 52.910  -31.390 114.044 1.00 58.03  ? 169 ALA D CA  1 
ATOM   9513  C C   . ALA D 1 150 ? 54.259  -31.786 113.462 1.00 59.75  ? 169 ALA D C   1 
ATOM   9514  O O   . ALA D 1 150 ? 55.179  -32.163 114.193 1.00 60.68  ? 169 ALA D O   1 
ATOM   9515  C CB  . ALA D 1 150 ? 51.943  -32.570 113.985 1.00 56.17  ? 169 ALA D CB  1 
ATOM   9516  N N   . ALA D 1 151 ? 54.390  -31.733 112.148 1.00 57.48  ? 170 ALA D N   1 
ATOM   9517  C CA  . ALA D 1 151 ? 55.679  -32.040 111.561 1.00 59.85  ? 170 ALA D CA  1 
ATOM   9518  C C   . ALA D 1 151 ? 56.714  -30.989 111.939 1.00 62.51  ? 170 ALA D C   1 
ATOM   9519  O O   . ALA D 1 151 ? 57.876  -31.333 112.186 1.00 64.62  ? 170 ALA D O   1 
ATOM   9520  C CB  . ALA D 1 151 ? 55.535  -32.161 110.049 1.00 61.86  ? 170 ALA D CB  1 
ATOM   9521  N N   . LYS D 1 152 ? 56.332  -29.701 111.979 1.00 60.11  ? 171 LYS D N   1 
ATOM   9522  C CA  . LYS D 1 152 ? 57.316  -28.676 112.323 1.00 63.42  ? 171 LYS D CA  1 
ATOM   9523  C C   . LYS D 1 152 ? 57.901  -28.949 113.702 1.00 62.19  ? 171 LYS D C   1 
ATOM   9524  O O   . LYS D 1 152 ? 59.098  -28.734 113.926 1.00 65.16  ? 171 LYS D O   1 
ATOM   9525  C CB  . LYS D 1 152 ? 56.702  -27.277 112.258 1.00 64.86  ? 171 LYS D CB  1 
ATOM   9526  N N   . ALA D 1 153 ? 57.088  -29.475 114.619 1.00 61.33  ? 172 ALA D N   1 
ATOM   9527  C CA  . ALA D 1 153 ? 57.587  -29.780 115.959 1.00 62.07  ? 172 ALA D CA  1 
ATOM   9528  C C   . ALA D 1 153 ? 58.453  -31.046 116.014 1.00 62.65  ? 172 ALA D C   1 
ATOM   9529  O O   . ALA D 1 153 ? 59.460  -31.071 116.742 1.00 64.81  ? 172 ALA D O   1 
ATOM   9530  C CB  . ALA D 1 153 ? 56.412  -29.921 116.931 1.00 59.99  ? 172 ALA D CB  1 
ATOM   9531  N N   . VAL D 1 154 ? 58.088  -32.102 115.262 1.00 61.47  ? 173 VAL D N   1 
ATOM   9532  C CA  . VAL D 1 154 ? 58.783  -33.385 115.411 1.00 62.42  ? 173 VAL D CA  1 
ATOM   9533  C C   . VAL D 1 154 ? 59.761  -33.713 114.281 1.00 64.79  ? 173 VAL D C   1 
ATOM   9534  O O   . VAL D 1 154 ? 60.766  -34.402 114.492 1.00 66.98  ? 173 VAL D O   1 
ATOM   9535  C CB  . VAL D 1 154 ? 57.768  -34.534 115.561 1.00 60.79  ? 173 VAL D CB  1 
ATOM   9536  C CG1 . VAL D 1 154 ? 56.635  -34.142 116.506 1.00 58.52  ? 173 VAL D CG1 1 
ATOM   9537  C CG2 . VAL D 1 154 ? 57.217  -34.919 114.209 1.00 60.43  ? 173 VAL D CG2 1 
ATOM   9538  N N   . VAL D 1 155 ? 59.477  -33.231 113.066 1.00 60.13  ? 174 VAL D N   1 
ATOM   9539  C CA  . VAL D 1 155 ? 60.472  -33.357 111.994 1.00 64.15  ? 174 VAL D CA  1 
ATOM   9540  C C   . VAL D 1 155 ? 61.533  -32.268 112.104 1.00 68.40  ? 174 VAL D C   1 
ATOM   9541  O O   . VAL D 1 155 ? 62.725  -32.547 112.290 1.00 71.39  ? 174 VAL D O   1 
ATOM   9542  C CB  . VAL D 1 155 ? 59.816  -33.331 110.601 1.00 64.76  ? 174 VAL D CB  1 
ATOM   9543  C CG1 . VAL D 1 155 ? 60.917  -33.379 109.523 1.00 69.64  ? 174 VAL D CG1 1 
ATOM   9544  C CG2 . VAL D 1 155 ? 58.825  -34.474 110.465 1.00 61.21  ? 174 VAL D CG2 1 
ATOM   9545  N N   . ASP D 1 156 ? 61.117  -31.009 111.940 1.00 69.05  ? 175 ASP D N   1 
ATOM   9546  C CA  . ASP D 1 156 ? 62.085  -29.912 111.941 1.00 73.49  ? 175 ASP D CA  1 
ATOM   9547  C C   . ASP D 1 156 ? 62.594  -29.652 113.351 1.00 72.99  ? 175 ASP D C   1 
ATOM   9548  O O   . ASP D 1 156 ? 63.746  -29.248 113.532 1.00 76.85  ? 175 ASP D O   1 
ATOM   9549  C CB  . ASP D 1 156 ? 61.467  -28.649 111.335 1.00 74.91  ? 175 ASP D CB  1 
ATOM   9550  N N   . GLY D 1 157 ? 61.774  -29.920 114.364 1.00 69.51  ? 176 GLY D N   1 
ATOM   9551  C CA  . GLY D 1 157 ? 62.191  -29.800 115.739 1.00 69.06  ? 176 GLY D CA  1 
ATOM   9552  C C   . GLY D 1 157 ? 62.601  -31.130 116.358 1.00 68.08  ? 176 GLY D C   1 
ATOM   9553  O O   . GLY D 1 157 ? 62.635  -32.181 115.709 1.00 68.11  ? 176 GLY D O   1 
ATOM   9554  N N   . THR D 1 158 ? 62.859  -31.078 117.670 1.00 66.74  ? 177 THR D N   1 
ATOM   9555  C CA  . THR D 1 158 ? 63.574  -32.128 118.390 1.00 66.88  ? 177 THR D CA  1 
ATOM   9556  C C   . THR D 1 158 ? 62.675  -33.166 119.071 1.00 64.25  ? 177 THR D C   1 
ATOM   9557  O O   . THR D 1 158 ? 63.198  -34.106 119.676 1.00 65.76  ? 177 THR D O   1 
ATOM   9558  C CB  . THR D 1 158 ? 64.501  -31.446 119.406 1.00 70.09  ? 177 THR D CB  1 
ATOM   9559  O OG1 . THR D 1 158 ? 65.076  -30.275 118.810 1.00 74.32  ? 177 THR D OG1 1 
ATOM   9560  C CG2 . THR D 1 158 ? 65.618  -32.343 119.828 1.00 72.28  ? 177 THR D CG2 1 
ATOM   9561  N N   . CYS D 1 159 ? 61.357  -33.058 118.946 1.00 65.82  ? 178 CYS D N   1 
ATOM   9562  C CA  . CYS D 1 159 ? 60.458  -34.059 119.497 1.00 63.45  ? 178 CYS D CA  1 
ATOM   9563  C C   . CYS D 1 159 ? 60.442  -35.330 118.642 1.00 62.92  ? 178 CYS D C   1 
ATOM   9564  O O   . CYS D 1 159 ? 60.733  -35.308 117.440 1.00 63.45  ? 178 CYS D O   1 
ATOM   9565  C CB  . CYS D 1 159 ? 59.019  -33.529 119.601 1.00 60.95  ? 178 CYS D CB  1 
ATOM   9566  S SG  . CYS D 1 159 ? 58.721  -32.214 120.837 1.00 61.55  ? 178 CYS D SG  1 
ATOM   9567  N N   . ASP D 1 160 ? 60.050  -36.442 119.282 1.00 58.81  ? 179 ASP D N   1 
ATOM   9568  C CA  . ASP D 1 160 ? 59.971  -37.761 118.651 1.00 58.33  ? 179 ASP D CA  1 
ATOM   9569  C C   . ASP D 1 160 ? 58.572  -38.132 118.169 1.00 55.25  ? 179 ASP D C   1 
ATOM   9570  O O   . ASP D 1 160 ? 58.413  -39.092 117.406 1.00 55.05  ? 179 ASP D O   1 
ATOM   9571  C CB  . ASP D 1 160 ? 60.430  -38.848 119.635 1.00 60.72  ? 179 ASP D CB  1 
ATOM   9572  C CG  . ASP D 1 160 ? 61.821  -38.599 120.157 1.00 64.03  ? 179 ASP D CG  1 
ATOM   9573  O OD1 . ASP D 1 160 ? 62.802  -38.918 119.429 1.00 66.28  ? 179 ASP D OD1 1 
ATOM   9574  O OD2 . ASP D 1 160 ? 61.929  -38.078 121.296 1.00 65.10  ? 179 ASP D OD2 1 
ATOM   9575  N N   . GLY D 1 161 ? 57.558  -37.416 118.618 1.00 55.78  ? 180 GLY D N   1 
ATOM   9576  C CA  . GLY D 1 161 ? 56.210  -37.782 118.250 1.00 52.71  ? 180 GLY D CA  1 
ATOM   9577  C C   . GLY D 1 161 ? 55.254  -36.725 118.734 1.00 51.09  ? 180 GLY D C   1 
ATOM   9578  O O   . GLY D 1 161 ? 55.644  -35.712 119.318 1.00 52.48  ? 180 GLY D O   1 
ATOM   9579  N N   . VAL D 1 162 ? 53.994  -36.994 118.482 1.00 49.60  ? 181 VAL D N   1 
ATOM   9580  C CA  . VAL D 1 162 ? 52.921  -36.059 118.742 1.00 48.19  ? 181 VAL D CA  1 
ATOM   9581  C C   . VAL D 1 162 ? 51.897  -36.758 119.610 1.00 46.86  ? 181 VAL D C   1 
ATOM   9582  O O   . VAL D 1 162 ? 51.750  -37.982 119.562 1.00 46.44  ? 181 VAL D O   1 
ATOM   9583  C CB  . VAL D 1 162 ? 52.327  -35.546 117.408 1.00 46.87  ? 181 VAL D CB  1 
ATOM   9584  C CG1 . VAL D 1 162 ? 51.735  -36.703 116.572 1.00 45.74  ? 181 VAL D CG1 1 
ATOM   9585  C CG2 . VAL D 1 162 ? 51.313  -34.439 117.670 1.00 46.37  ? 181 VAL D CG2 1 
ATOM   9586  N N   . PHE D 1 163 ? 51.225  -35.977 120.448 1.00 46.01  ? 182 PHE D N   1 
ATOM   9587  C CA  . PHE D 1 163 ? 50.144  -36.476 121.286 1.00 44.97  ? 182 PHE D CA  1 
ATOM   9588  C C   . PHE D 1 163 ? 48.846  -35.882 120.764 1.00 43.51  ? 182 PHE D C   1 
ATOM   9589  O O   . PHE D 1 163 ? 48.638  -34.676 120.874 1.00 44.56  ? 182 PHE D O   1 
ATOM   9590  C CB  . PHE D 1 163 ? 50.346  -36.115 122.747 1.00 46.85  ? 182 PHE D CB  1 
ATOM   9591  C CG  . PHE D 1 163 ? 49.271  -36.640 123.655 1.00 46.49  ? 182 PHE D CG  1 
ATOM   9592  C CD1 . PHE D 1 163 ? 48.129  -35.905 123.906 1.00 46.13  ? 182 PHE D CD1 1 
ATOM   9593  C CD2 . PHE D 1 163 ? 49.419  -37.861 124.289 1.00 47.26  ? 182 PHE D CD2 1 
ATOM   9594  C CE1 . PHE D 1 163 ? 47.156  -36.378 124.757 1.00 46.18  ? 182 PHE D CE1 1 
ATOM   9595  C CE2 . PHE D 1 163 ? 48.445  -38.332 125.158 1.00 47.17  ? 182 PHE D CE2 1 
ATOM   9596  C CZ  . PHE D 1 163 ? 47.315  -37.594 125.379 1.00 46.40  ? 182 PHE D CZ  1 
ATOM   9597  N N   . MET D 1 164 ? 47.969  -36.738 120.241 1.00 44.63  ? 183 MET D N   1 
ATOM   9598  C CA  . MET D 1 164 ? 46.758  -36.337 119.535 1.00 43.81  ? 183 MET D CA  1 
ATOM   9599  C C   . MET D 1 164 ? 45.569  -36.475 120.480 1.00 43.34  ? 183 MET D C   1 
ATOM   9600  O O   . MET D 1 164 ? 44.981  -37.543 120.606 1.00 42.52  ? 183 MET D O   1 
ATOM   9601  C CB  . MET D 1 164 ? 46.572  -37.204 118.289 1.00 42.19  ? 183 MET D CB  1 
ATOM   9602  C CG  . MET D 1 164 ? 47.657  -37.062 117.226 1.00 43.50  ? 183 MET D CG  1 
ATOM   9603  S SD  . MET D 1 164 ? 47.300  -38.066 115.737 1.00 42.95  ? 183 MET D SD  1 
ATOM   9604  C CE  . MET D 1 164 ? 46.004  -37.165 114.932 1.00 42.58  ? 183 MET D CE  1 
ATOM   9605  N N   . ASP D 1 165 ? 45.175  -35.383 121.094 1.00 38.44  ? 184 ASP D N   1 
ATOM   9606  C CA  . ASP D 1 165 ? 44.179  -35.386 122.153 1.00 39.36  ? 184 ASP D CA  1 
ATOM   9607  C C   . ASP D 1 165 ? 42.780  -35.233 121.585 1.00 39.75  ? 184 ASP D C   1 
ATOM   9608  O O   . ASP D 1 165 ? 42.593  -34.843 120.437 1.00 39.77  ? 184 ASP D O   1 
ATOM   9609  C CB  . ASP D 1 165 ? 44.476  -34.240 123.122 1.00 41.85  ? 184 ASP D CB  1 
ATOM   9610  C CG  . ASP D 1 165 ? 43.926  -34.470 124.500 1.00 43.40  ? 184 ASP D CG  1 
ATOM   9611  O OD1 . ASP D 1 165 ? 43.113  -35.408 124.691 1.00 43.09  ? 184 ASP D OD1 1 
ATOM   9612  O OD2 . ASP D 1 165 ? 44.305  -33.664 125.380 1.00 45.34  ? 184 ASP D OD2 1 
ATOM   9613  N N   . ALA D 1 166 ? 41.795  -35.626 122.380 1.00 37.84  ? 185 ALA D N   1 
ATOM   9614  C CA  . ALA D 1 166 ? 40.393  -35.271 122.226 1.00 39.73  ? 185 ALA D CA  1 
ATOM   9615  C C   . ALA D 1 166 ? 39.612  -36.147 121.264 1.00 38.12  ? 185 ALA D C   1 
ATOM   9616  O O   . ALA D 1 166 ? 38.522  -35.733 120.814 1.00 40.42  ? 185 ALA D O   1 
ATOM   9617  C CB  . ALA D 1 166 ? 40.246  -33.810 121.790 1.00 42.02  ? 185 ALA D CB  1 
ATOM   9618  N N   . PHE D 1 167 ? 40.072  -37.352 120.929 1.00 39.92  ? 186 PHE D N   1 
ATOM   9619  C CA  . PHE D 1 167 ? 39.267  -38.228 120.080 1.00 39.04  ? 186 PHE D CA  1 
ATOM   9620  C C   . PHE D 1 167 ? 37.895  -38.531 120.669 1.00 40.51  ? 186 PHE D C   1 
ATOM   9621  O O   . PHE D 1 167 ? 36.909  -38.503 119.920 1.00 42.23  ? 186 PHE D O   1 
ATOM   9622  C CB  . PHE D 1 167 ? 40.001  -39.532 119.816 1.00 36.68  ? 186 PHE D CB  1 
ATOM   9623  C CG  . PHE D 1 167 ? 41.141  -39.417 118.848 1.00 35.76  ? 186 PHE D CG  1 
ATOM   9624  C CD1 . PHE D 1 167 ? 41.829  -38.225 118.681 1.00 36.67  ? 186 PHE D CD1 1 
ATOM   9625  C CD2 . PHE D 1 167 ? 41.528  -40.511 118.104 1.00 34.87  ? 186 PHE D CD2 1 
ATOM   9626  C CE1 . PHE D 1 167 ? 42.876  -38.122 117.802 1.00 35.99  ? 186 PHE D CE1 1 
ATOM   9627  C CE2 . PHE D 1 167 ? 42.595  -40.411 117.233 1.00 34.51  ? 186 PHE D CE2 1 
ATOM   9628  C CZ  . PHE D 1 167 ? 43.266  -39.199 117.087 1.00 35.14  ? 186 PHE D CZ  1 
ATOM   9629  N N   . PRO D 1 168 ? 37.741  -38.809 121.956 1.00 36.08  ? 187 PRO D N   1 
ATOM   9630  C CA  . PRO D 1 168 ? 36.373  -38.930 122.476 1.00 37.29  ? 187 PRO D CA  1 
ATOM   9631  C C   . PRO D 1 168 ? 35.542  -37.674 122.261 1.00 40.09  ? 187 PRO D C   1 
ATOM   9632  O O   . PRO D 1 168 ? 34.328  -37.777 122.056 1.00 41.66  ? 187 PRO D O   1 
ATOM   9633  C CB  . PRO D 1 168 ? 36.587  -39.229 123.965 1.00 36.80  ? 187 PRO D CB  1 
ATOM   9634  C CG  . PRO D 1 168 ? 37.951  -39.810 124.049 1.00 35.25  ? 187 PRO D CG  1 
ATOM   9635  C CD  . PRO D 1 168 ? 38.765  -39.146 122.971 1.00 35.39  ? 187 PRO D CD  1 
ATOM   9636  N N   . GLN D 1 169 ? 36.138  -36.476 122.289 1.00 38.41  ? 188 GLN D N   1 
ATOM   9637  C CA  . GLN D 1 169 ? 35.314  -35.288 122.068 1.00 40.47  ? 188 GLN D CA  1 
ATOM   9638  C C   . GLN D 1 169 ? 34.837  -35.213 120.618 1.00 41.88  ? 188 GLN D C   1 
ATOM   9639  O O   . GLN D 1 169 ? 33.674  -34.890 120.357 1.00 43.24  ? 188 GLN D O   1 
ATOM   9640  C CB  . GLN D 1 169 ? 36.081  -34.031 122.465 1.00 41.32  ? 188 GLN D CB  1 
ATOM   9641  C CG  . GLN D 1 169 ? 36.726  -34.051 123.822 1.00 40.41  ? 188 GLN D CG  1 
ATOM   9642  C CD  . GLN D 1 169 ? 37.114  -32.644 124.254 1.00 42.26  ? 188 GLN D CD  1 
ATOM   9643  O OE1 . GLN D 1 169 ? 36.291  -31.729 124.162 1.00 43.56  ? 188 GLN D OE1 1 
ATOM   9644  N NE2 . GLN D 1 169 ? 38.377  -32.448 124.687 1.00 42.85  ? 188 GLN D NE2 1 
ATOM   9645  N N   . ILE D 1 170 ? 35.714  -35.546 119.670 1.00 40.75  ? 189 ILE D N   1 
ATOM   9646  C CA  . ILE D 1 170 ? 35.336  -35.571 118.259 1.00 41.75  ? 189 ILE D CA  1 
ATOM   9647  C C   . ILE D 1 170 ? 34.195  -36.554 117.995 1.00 41.95  ? 189 ILE D C   1 
ATOM   9648  O O   . ILE D 1 170 ? 33.319  -36.297 117.167 1.00 43.85  ? 189 ILE D O   1 
ATOM   9649  C CB  . ILE D 1 170 ? 36.546  -35.947 117.385 1.00 39.47  ? 189 ILE D CB  1 
ATOM   9650  C CG1 . ILE D 1 170 ? 37.657  -34.922 117.492 1.00 38.73  ? 189 ILE D CG1 1 
ATOM   9651  C CG2 . ILE D 1 170 ? 36.102  -36.102 115.950 1.00 39.93  ? 189 ILE D CG2 1 
ATOM   9652  C CD1 . ILE D 1 170 ? 38.997  -35.442 116.952 1.00 35.82  ? 189 ILE D CD1 1 
ATOM   9653  N N   . ALA D 1 171 ? 34.228  -37.722 118.642 1.00 40.39  ? 190 ALA D N   1 
ATOM   9654  C CA  . ALA D 1 171 ? 33.343  -38.826 118.312 1.00 40.97  ? 190 ALA D CA  1 
ATOM   9655  C C   . ALA D 1 171 ? 32.038  -38.806 119.070 1.00 42.55  ? 190 ALA D C   1 
ATOM   9656  O O   . ALA D 1 171 ? 31.172  -39.641 118.782 1.00 43.97  ? 190 ALA D O   1 
ATOM   9657  C CB  . ALA D 1 171 ? 34.025  -40.158 118.609 1.00 38.39  ? 190 ALA D CB  1 
ATOM   9658  N N   . SER D 1 172 ? 31.901  -37.930 120.062 1.00 40.34  ? 191 SER D N   1 
ATOM   9659  C CA  . SER D 1 172 ? 30.692  -37.909 120.864 1.00 41.23  ? 191 SER D CA  1 
ATOM   9660  C C   . SER D 1 172 ? 29.482  -37.853 119.949 1.00 43.96  ? 191 SER D C   1 
ATOM   9661  O O   . SER D 1 172 ? 29.421  -37.043 119.019 1.00 44.48  ? 191 SER D O   1 
ATOM   9662  C CB  . SER D 1 172 ? 30.678  -36.706 121.805 1.00 41.68  ? 191 SER D CB  1 
ATOM   9663  O OG  . SER D 1 172 ? 29.462  -36.682 122.552 1.00 43.48  ? 191 SER D OG  1 
ATOM   9664  N N   . GLN D 1 173 ? 28.526  -38.733 120.197 1.00 42.70  ? 192 GLN D N   1 
ATOM   9665  C CA  . GLN D 1 173 ? 27.342  -38.744 119.342 1.00 45.72  ? 192 GLN D CA  1 
ATOM   9666  C C   . GLN D 1 173 ? 26.547  -37.443 119.471 1.00 47.35  ? 192 GLN D C   1 
ATOM   9667  O O   . GLN D 1 173 ? 25.728  -37.146 118.593 1.00 49.33  ? 192 GLN D O   1 
ATOM   9668  C CB  . GLN D 1 173 ? 26.489  -39.976 119.662 1.00 47.44  ? 192 GLN D CB  1 
ATOM   9669  C CG  . GLN D 1 173 ? 27.137  -41.334 119.308 1.00 46.91  ? 192 GLN D CG  1 
ATOM   9670  C CD  . GLN D 1 173 ? 27.383  -41.513 117.823 1.00 47.56  ? 192 GLN D CD  1 
ATOM   9671  O OE1 . GLN D 1 173 ? 26.509  -41.260 117.001 1.00 49.82  ? 192 GLN D OE1 1 
ATOM   9672  N NE2 . GLN D 1 173 ? 28.595  -41.961 117.475 1.00 46.00  ? 192 GLN D NE2 1 
ATOM   9673  N N   . ALA D 1 174 ? 26.809  -36.646 120.526 1.00 46.59  ? 193 ALA D N   1 
ATOM   9674  C CA  . ALA D 1 174 ? 26.064  -35.410 120.727 1.00 47.24  ? 193 ALA D CA  1 
ATOM   9675  C C   . ALA D 1 174 ? 26.385  -34.392 119.651 1.00 47.06  ? 193 ALA D C   1 
ATOM   9676  O O   . ALA D 1 174 ? 25.513  -33.607 119.259 1.00 48.34  ? 193 ALA D O   1 
ATOM   9677  C CB  . ALA D 1 174 ? 26.369  -34.814 122.092 1.00 45.94  ? 193 ALA D CB  1 
ATOM   9678  N N   . ASN D 1 175 ? 27.610  -34.398 119.156 1.00 47.14  ? 194 ASN D N   1 
ATOM   9679  C CA  . ASN D 1 175 ? 27.959  -33.552 118.033 1.00 47.51  ? 194 ASN D CA  1 
ATOM   9680  C C   . ASN D 1 175 ? 27.031  -33.759 116.837 1.00 49.68  ? 194 ASN D C   1 
ATOM   9681  O O   . ASN D 1 175 ? 27.033  -32.947 115.916 1.00 50.05  ? 194 ASN D O   1 
ATOM   9682  C CB  . ASN D 1 175 ? 29.401  -33.793 117.585 1.00 45.99  ? 194 ASN D CB  1 
ATOM   9683  C CG  . ASN D 1 175 ? 30.392  -33.439 118.635 1.00 44.31  ? 194 ASN D CG  1 
ATOM   9684  O OD1 . ASN D 1 175 ? 30.131  -32.609 119.489 1.00 44.26  ? 194 ASN D OD1 1 
ATOM   9685  N ND2 . ASN D 1 175 ? 31.547  -34.050 118.580 1.00 43.21  ? 194 ASN D ND2 1 
ATOM   9686  N N   . ARG D 1 176 ? 26.246  -34.840 116.812 1.00 47.51  ? 195 ARG D N   1 
ATOM   9687  C CA  . ARG D 1 176 ? 25.323  -35.020 115.691 1.00 49.22  ? 195 ARG D CA  1 
ATOM   9688  C C   . ARG D 1 176 ? 24.225  -33.973 115.729 1.00 50.52  ? 195 ARG D C   1 
ATOM   9689  O O   . ARG D 1 176 ? 23.767  -33.521 114.676 1.00 51.90  ? 195 ARG D O   1 
ATOM   9690  C CB  . ARG D 1 176 ? 24.696  -36.433 115.705 1.00 50.28  ? 195 ARG D CB  1 
ATOM   9691  C CG  . ARG D 1 176 ? 25.603  -37.583 115.180 1.00 49.51  ? 195 ARG D CG  1 
ATOM   9692  C CD  . ARG D 1 176 ? 24.894  -38.955 115.246 1.00 51.04  ? 195 ARG D CD  1 
ATOM   9693  N NE  . ARG D 1 176 ? 25.746  -40.051 114.801 1.00 50.61  ? 195 ARG D NE  1 
ATOM   9694  C CZ  . ARG D 1 176 ? 25.853  -40.449 113.542 1.00 51.43  ? 195 ARG D CZ  1 
ATOM   9695  N NH1 . ARG D 1 176 ? 25.158  -39.874 112.569 1.00 52.84  ? 195 ARG D NH1 1 
ATOM   9696  N NH2 . ARG D 1 176 ? 26.669  -41.456 113.252 1.00 50.49  ? 195 ARG D NH2 1 
ATOM   9697  N N   . LYS D 1 177 ? 23.800  -33.582 116.934 1.00 50.69  ? 196 LYS D N   1 
ATOM   9698  C CA  . LYS D 1 177 ? 22.778  -32.553 117.074 1.00 51.87  ? 196 LYS D CA  1 
ATOM   9699  C C   . LYS D 1 177 ? 23.289  -31.205 116.576 1.00 50.66  ? 196 LYS D C   1 
ATOM   9700  O O   . LYS D 1 177 ? 22.503  -30.390 116.077 1.00 51.47  ? 196 LYS D O   1 
ATOM   9701  C CB  . LYS D 1 177 ? 22.331  -32.465 118.534 1.00 52.97  ? 196 LYS D CB  1 
ATOM   9702  N N   . LEU D 1 178 ? 24.586  -30.958 116.668 1.00 52.68  ? 197 LEU D N   1 
ATOM   9703  C CA  . LEU D 1 178 ? 25.142  -29.690 116.244 1.00 52.23  ? 197 LEU D CA  1 
ATOM   9704  C C   . LEU D 1 178 ? 25.510  -29.627 114.779 1.00 52.30  ? 197 LEU D C   1 
ATOM   9705  O O   . LEU D 1 178 ? 25.522  -28.525 114.206 1.00 52.41  ? 197 LEU D O   1 
ATOM   9706  C CB  . LEU D 1 178 ? 26.425  -29.370 117.000 1.00 51.36  ? 197 LEU D CB  1 
ATOM   9707  C CG  . LEU D 1 178 ? 26.320  -29.380 118.515 1.00 52.19  ? 197 LEU D CG  1 
ATOM   9708  C CD1 . LEU D 1 178 ? 27.743  -29.233 119.104 1.00 50.91  ? 197 LEU D CD1 1 
ATOM   9709  C CD2 . LEU D 1 178 ? 25.364  -28.261 118.958 1.00 53.38  ? 197 LEU D CD2 1 
ATOM   9710  N N   . TRP D 1 179 ? 25.844  -30.767 114.157 1.00 53.42  ? 198 TRP D N   1 
ATOM   9711  C CA  . TRP D 1 179 ? 26.413  -30.716 112.823 1.00 53.32  ? 198 TRP D CA  1 
ATOM   9712  C C   . TRP D 1 179 ? 25.550  -31.326 111.738 1.00 54.60  ? 198 TRP D C   1 
ATOM   9713  O O   . TRP D 1 179 ? 25.807  -31.065 110.557 1.00 55.32  ? 198 TRP D O   1 
ATOM   9714  C CB  . TRP D 1 179 ? 27.766  -31.439 112.770 1.00 52.03  ? 198 TRP D CB  1 
ATOM   9715  C CG  . TRP D 1 179 ? 28.796  -30.916 113.706 1.00 50.51  ? 198 TRP D CG  1 
ATOM   9716  C CD1 . TRP D 1 179 ? 28.915  -29.659 114.174 1.00 50.21  ? 198 TRP D CD1 1 
ATOM   9717  C CD2 . TRP D 1 179 ? 29.846  -31.669 114.303 1.00 49.45  ? 198 TRP D CD2 1 
ATOM   9718  N NE1 . TRP D 1 179 ? 29.987  -29.566 115.020 1.00 49.18  ? 198 TRP D NE1 1 
ATOM   9719  C CE2 . TRP D 1 179 ? 30.576  -30.795 115.115 1.00 48.73  ? 198 TRP D CE2 1 
ATOM   9720  C CE3 . TRP D 1 179 ? 30.241  -33.002 114.228 1.00 49.13  ? 198 TRP D CE3 1 
ATOM   9721  C CZ2 . TRP D 1 179 ? 31.686  -31.209 115.840 1.00 47.65  ? 198 TRP D CZ2 1 
ATOM   9722  C CZ3 . TRP D 1 179 ? 31.333  -33.404 114.940 1.00 48.03  ? 198 TRP D CZ3 1 
ATOM   9723  C CH2 . TRP D 1 179 ? 32.037  -32.524 115.746 1.00 47.51  ? 198 TRP D CH2 1 
ATOM   9724  N N   . GLY D 1 180 ? 24.561  -32.146 112.090 1.00 53.67  ? 199 GLY D N   1 
ATOM   9725  C CA  . GLY D 1 180 ? 23.909  -32.987 111.095 1.00 55.38  ? 199 GLY D CA  1 
ATOM   9726  C C   . GLY D 1 180 ? 24.704  -34.266 110.866 1.00 55.59  ? 199 GLY D C   1 
ATOM   9727  O O   . GLY D 1 180 ? 25.931  -34.272 110.999 1.00 54.13  ? 199 GLY D O   1 
ATOM   9728  N N   . ASP D 1 181 ? 24.033  -35.357 110.504 1.00 53.79  ? 200 ASP D N   1 
ATOM   9729  C CA  . ASP D 1 181 ? 24.748  -36.626 110.403 1.00 52.79  ? 200 ASP D CA  1 
ATOM   9730  C C   . ASP D 1 181 ? 25.771  -36.622 109.264 1.00 54.27  ? 200 ASP D C   1 
ATOM   9731  O O   . ASP D 1 181 ? 26.902  -37.100 109.452 1.00 53.49  ? 200 ASP D O   1 
ATOM   9732  C CB  . ASP D 1 181 ? 23.754  -37.772 110.228 1.00 53.97  ? 200 ASP D CB  1 
ATOM   9733  C CG  . ASP D 1 181 ? 22.873  -37.967 111.441 1.00 54.76  ? 200 ASP D CG  1 
ATOM   9734  O OD1 . ASP D 1 181 ? 23.306  -37.691 112.572 1.00 53.50  ? 200 ASP D OD1 1 
ATOM   9735  O OD2 . ASP D 1 181 ? 21.726  -38.398 111.277 1.00 57.46  ? 200 ASP D OD2 1 
ATOM   9736  N N   . GLU D 1 182 ? 25.403  -36.094 108.085 1.00 53.33  ? 201 GLU D N   1 
ATOM   9737  C CA  . GLU D 1 182 ? 26.344  -36.058 106.965 1.00 55.19  ? 201 GLU D CA  1 
ATOM   9738  C C   . GLU D 1 182 ? 27.659  -35.392 107.392 1.00 53.95  ? 201 GLU D C   1 
ATOM   9739  O O   . GLU D 1 182 ? 28.739  -35.929 107.147 1.00 53.93  ? 201 GLU D O   1 
ATOM   9740  C CB  . GLU D 1 182 ? 25.722  -35.343 105.766 1.00 58.48  ? 201 GLU D CB  1 
ATOM   9741  N N   . LYS D 1 183 ? 27.586  -34.235 108.063 1.00 55.96  ? 202 LYS D N   1 
ATOM   9742  C CA  . LYS D 1 183 ? 28.810  -33.531 108.464 1.00 54.49  ? 202 LYS D CA  1 
ATOM   9743  C C   . LYS D 1 183 ? 29.497  -34.256 109.620 1.00 53.32  ? 202 LYS D C   1 
ATOM   9744  O O   . LYS D 1 183 ? 30.736  -34.356 109.659 1.00 53.10  ? 202 LYS D O   1 
ATOM   9745  C CB  . LYS D 1 183 ? 28.473  -32.061 108.798 1.00 53.40  ? 202 LYS D CB  1 
ATOM   9746  C CG  . LYS D 1 183 ? 29.574  -31.160 109.443 1.00 51.33  ? 202 LYS D CG  1 
ATOM   9747  C CD  . LYS D 1 183 ? 30.857  -30.966 108.614 1.00 51.85  ? 202 LYS D CD  1 
ATOM   9748  C CE  . LYS D 1 183 ? 30.956  -29.610 107.965 1.00 52.27  ? 202 LYS D CE  1 
ATOM   9749  N NZ  . LYS D 1 183 ? 32.171  -29.631 107.086 1.00 52.89  ? 202 LYS D NZ  1 
ATOM   9750  N N   . PHE D 1 184 ? 28.712  -34.816 110.542 1.00 56.35  ? 203 PHE D N   1 
ATOM   9751  C CA  . PHE D 1 184 ? 29.277  -35.704 111.549 1.00 54.78  ? 203 PHE D CA  1 
ATOM   9752  C C   . PHE D 1 184 ? 30.065  -36.838 110.918 1.00 55.14  ? 203 PHE D C   1 
ATOM   9753  O O   . PHE D 1 184 ? 31.152  -37.190 111.374 1.00 53.82  ? 203 PHE D O   1 
ATOM   9754  C CB  . PHE D 1 184 ? 28.168  -36.296 112.413 1.00 52.81  ? 203 PHE D CB  1 
ATOM   9755  C CG  . PHE D 1 184 ? 28.666  -37.226 113.491 1.00 48.42  ? 203 PHE D CG  1 
ATOM   9756  C CD1 . PHE D 1 184 ? 28.982  -36.734 114.759 1.00 45.30  ? 203 PHE D CD1 1 
ATOM   9757  C CD2 . PHE D 1 184 ? 28.815  -38.581 113.255 1.00 47.56  ? 203 PHE D CD2 1 
ATOM   9758  C CE1 . PHE D 1 184 ? 29.440  -37.587 115.782 1.00 41.95  ? 203 PHE D CE1 1 
ATOM   9759  C CE2 . PHE D 1 184 ? 29.276  -39.454 114.260 1.00 43.62  ? 203 PHE D CE2 1 
ATOM   9760  C CZ  . PHE D 1 184 ? 29.594  -38.960 115.528 1.00 41.29  ? 203 PHE D CZ  1 
ATOM   9761  N N   . GLU D 1 185 ? 29.489  -37.479 109.908 1.00 56.14  ? 204 GLU D N   1 
ATOM   9762  C CA  . GLU D 1 185 ? 30.180  -38.608 109.280 1.00 56.66  ? 204 GLU D CA  1 
ATOM   9763  C C   . GLU D 1 185 ? 31.441  -38.126 108.568 1.00 58.60  ? 204 GLU D C   1 
ATOM   9764  O O   . GLU D 1 185 ? 32.461  -38.822 108.539 1.00 59.03  ? 204 GLU D O   1 
ATOM   9765  C CB  . GLU D 1 185 ? 29.242  -39.332 108.300 1.00 58.30  ? 204 GLU D CB  1 
ATOM   9766  C CG  . GLU D 1 185 ? 28.121  -40.206 108.936 1.00 56.78  ? 204 GLU D CG  1 
ATOM   9767  C CD  . GLU D 1 185 ? 28.599  -41.356 109.897 1.00 54.22  ? 204 GLU D CD  1 
ATOM   9768  O OE1 . GLU D 1 185 ? 29.819  -41.781 109.864 1.00 53.81  ? 204 GLU D OE1 1 
ATOM   9769  O OE2 . GLU D 1 185 ? 27.722  -41.867 110.680 1.00 52.68  ? 204 GLU D OE2 1 
ATOM   9770  N N   . ALA D 1 186 ? 31.387  -36.927 108.002 1.00 52.47  ? 205 ALA D N   1 
ATOM   9771  C CA  . ALA D 1 186 ? 32.516  -36.426 107.238 1.00 53.73  ? 205 ALA D CA  1 
ATOM   9772  C C   . ALA D 1 186 ? 33.674  -36.095 108.147 1.00 52.80  ? 205 ALA D C   1 
ATOM   9773  O O   . ALA D 1 186 ? 34.841  -36.182 107.742 1.00 53.69  ? 205 ALA D O   1 
ATOM   9774  C CB  . ALA D 1 186 ? 32.089  -35.196 106.449 1.00 53.74  ? 205 ALA D CB  1 
ATOM   9775  N N   . ILE D 1 187 ? 33.350  -35.700 109.369 1.00 55.55  ? 206 ILE D N   1 
ATOM   9776  C CA  . ILE D 1 187 ? 34.362  -35.343 110.348 1.00 53.51  ? 206 ILE D CA  1 
ATOM   9777  C C   . ILE D 1 187 ? 35.041  -36.585 110.924 1.00 54.91  ? 206 ILE D C   1 
ATOM   9778  O O   . ILE D 1 187 ? 36.271  -36.616 111.033 1.00 52.82  ? 206 ILE D O   1 
ATOM   9779  C CB  . ILE D 1 187 ? 33.716  -34.450 111.430 1.00 49.64  ? 206 ILE D CB  1 
ATOM   9780  C CG1 . ILE D 1 187 ? 33.571  -33.037 110.853 1.00 48.39  ? 206 ILE D CG1 1 
ATOM   9781  C CG2 . ILE D 1 187 ? 34.514  -34.507 112.719 1.00 44.22  ? 206 ILE D CG2 1 
ATOM   9782  C CD1 . ILE D 1 187 ? 32.857  -32.094 111.769 1.00 45.41  ? 206 ILE D CD1 1 
ATOM   9783  N N   . GLN D 1 188 ? 34.269  -37.624 111.283 1.00 54.58  ? 207 GLN D N   1 
ATOM   9784  C CA  . GLN D 1 188 ? 34.876  -38.881 111.729 1.00 51.59  ? 207 GLN D CA  1 
ATOM   9785  C C   . GLN D 1 188 ? 35.823  -39.432 110.672 1.00 55.76  ? 207 GLN D C   1 
ATOM   9786  O O   . GLN D 1 188 ? 36.940  -39.864 110.981 1.00 55.35  ? 207 GLN D O   1 
ATOM   9787  C CB  . GLN D 1 188 ? 33.807  -39.918 112.052 1.00 48.39  ? 207 GLN D CB  1 
ATOM   9788  C CG  . GLN D 1 188 ? 32.711  -39.472 112.986 1.00 45.05  ? 207 GLN D CG  1 
ATOM   9789  C CD  . GLN D 1 188 ? 33.206  -38.581 114.151 1.00 41.22  ? 207 GLN D CD  1 
ATOM   9790  O OE1 . GLN D 1 188 ? 34.116  -38.951 114.931 1.00 38.01  ? 207 GLN D OE1 1 
ATOM   9791  N NE2 . GLN D 1 188 ? 32.603  -37.392 114.268 1.00 41.88  ? 207 GLN D NE2 1 
ATOM   9792  N N   . GLN D 1 189 ? 35.393  -39.400 109.416 1.00 51.35  ? 208 GLN D N   1 
ATOM   9793  C CA  . GLN D 1 189 ? 36.261  -39.715 108.290 1.00 54.37  ? 208 GLN D CA  1 
ATOM   9794  C C   . GLN D 1 189 ? 37.445  -38.761 108.202 1.00 56.03  ? 208 GLN D C   1 
ATOM   9795  O O   . GLN D 1 189 ? 38.535  -39.166 107.787 1.00 57.69  ? 208 GLN D O   1 
ATOM   9796  C CB  . GLN D 1 189 ? 35.439  -39.648 107.002 1.00 55.56  ? 208 GLN D CB  1 
ATOM   9797  C CG  . GLN D 1 189 ? 36.245  -39.884 105.777 1.00 58.46  ? 208 GLN D CG  1 
ATOM   9798  C CD  . GLN D 1 189 ? 36.794  -41.254 105.785 1.00 59.23  ? 208 GLN D CD  1 
ATOM   9799  O OE1 . GLN D 1 189 ? 36.071  -42.194 106.083 1.00 58.28  ? 208 GLN D OE1 1 
ATOM   9800  N NE2 . GLN D 1 189 ? 38.088  -41.388 105.505 1.00 61.19  ? 208 GLN D NE2 1 
ATOM   9801  N N   . GLY D 1 190 ? 37.235  -37.475 108.533 1.00 57.31  ? 209 GLY D N   1 
ATOM   9802  C CA  . GLY D 1 190 ? 38.349  -36.539 108.585 1.00 55.19  ? 209 GLY D CA  1 
ATOM   9803  C C   . GLY D 1 190 ? 39.363  -36.922 109.644 1.00 53.27  ? 209 GLY D C   1 
ATOM   9804  O O   . GLY D 1 190 ? 40.571  -36.764 109.453 1.00 52.36  ? 209 GLY D O   1 
ATOM   9805  N N   . LEU D 1 191 ? 38.883  -37.460 110.766 1.00 56.48  ? 210 LEU D N   1 
ATOM   9806  C CA  . LEU D 1 191 ? 39.780  -37.965 111.802 1.00 51.81  ? 210 LEU D CA  1 
ATOM   9807  C C   . LEU D 1 191 ? 40.661  -39.077 111.254 1.00 56.46  ? 210 LEU D C   1 
ATOM   9808  O O   . LEU D 1 191 ? 41.887  -39.042 111.375 1.00 55.27  ? 210 LEU D O   1 
ATOM   9809  C CB  . LEU D 1 191 ? 38.957  -38.443 112.993 1.00 46.51  ? 210 LEU D CB  1 
ATOM   9810  C CG  . LEU D 1 191 ? 39.722  -39.002 114.179 1.00 41.25  ? 210 LEU D CG  1 
ATOM   9811  C CD1 . LEU D 1 191 ? 40.798  -38.048 114.683 1.00 37.70  ? 210 LEU D CD1 1 
ATOM   9812  C CD2 . LEU D 1 191 ? 38.769  -39.297 115.324 1.00 36.45  ? 210 LEU D CD2 1 
ATOM   9813  N N   . GLN D 1 192 ? 40.055  -40.051 110.605 1.00 53.64  ? 211 GLN D N   1 
ATOM   9814  C CA  . GLN D 1 192 ? 40.844  -41.071 109.929 1.00 56.52  ? 211 GLN D CA  1 
ATOM   9815  C C   . GLN D 1 192 ? 41.909  -40.443 109.046 1.00 60.74  ? 211 GLN D C   1 
ATOM   9816  O O   . GLN D 1 192 ? 43.088  -40.809 109.103 1.00 61.57  ? 211 GLN D O   1 
ATOM   9817  C CB  . GLN D 1 192 ? 39.920  -41.951 109.096 1.00 56.58  ? 211 GLN D CB  1 
ATOM   9818  C CG  . GLN D 1 192 ? 39.530  -43.195 109.803 1.00 52.90  ? 211 GLN D CG  1 
ATOM   9819  C CD  . GLN D 1 192 ? 40.333  -44.370 109.300 1.00 55.00  ? 211 GLN D CD  1 
ATOM   9820  O OE1 . GLN D 1 192 ? 41.030  -44.277 108.266 1.00 59.76  ? 211 GLN D OE1 1 
ATOM   9821  N NE2 . GLN D 1 192 ? 40.233  -45.503 110.006 1.00 51.85  ? 211 GLN D NE2 1 
ATOM   9822  N N   . ASP D 1 193 ? 41.501  -39.479 108.227 1.00 59.08  ? 212 ASP D N   1 
ATOM   9823  C CA  . ASP D 1 193 ? 42.405  -38.896 107.243 1.00 59.00  ? 212 ASP D CA  1 
ATOM   9824  C C   . ASP D 1 193 ? 43.534  -38.134 107.911 1.00 55.20  ? 212 ASP D C   1 
ATOM   9825  O O   . ASP D 1 193 ? 44.690  -38.198 107.472 1.00 56.17  ? 212 ASP D O   1 
ATOM   9826  C CB  . ASP D 1 193 ? 41.618  -37.972 106.318 1.00 59.03  ? 212 ASP D CB  1 
ATOM   9827  C CG  . ASP D 1 193 ? 40.764  -38.731 105.318 1.00 62.50  ? 212 ASP D CG  1 
ATOM   9828  O OD1 . ASP D 1 193 ? 41.104  -39.900 104.986 1.00 65.73  ? 212 ASP D OD1 1 
ATOM   9829  O OD2 . ASP D 1 193 ? 39.750  -38.144 104.862 1.00 62.19  ? 212 ASP D OD2 1 
ATOM   9830  N N   . ILE D 1 194 ? 43.219  -37.407 108.972 1.00 61.21  ? 213 ILE D N   1 
ATOM   9831  C CA  . ILE D 1 194 ? 44.256  -36.621 109.620 1.00 56.56  ? 213 ILE D CA  1 
ATOM   9832  C C   . ILE D 1 194 ? 45.290  -37.530 110.291 1.00 56.08  ? 213 ILE D C   1 
ATOM   9833  O O   . ILE D 1 194 ? 46.457  -37.140 110.455 1.00 54.66  ? 213 ILE D O   1 
ATOM   9834  C CB  . ILE D 1 194 ? 43.606  -35.642 110.625 1.00 51.17  ? 213 ILE D CB  1 
ATOM   9835  C CG1 . ILE D 1 194 ? 44.369  -34.305 110.682 1.00 47.17  ? 213 ILE D CG1 1 
ATOM   9836  C CG2 . ILE D 1 194 ? 43.476  -36.359 111.992 1.00 47.79  ? 213 ILE D CG2 1 
ATOM   9837  C CD1 . ILE D 1 194 ? 43.702  -33.274 111.579 1.00 43.74  ? 213 ILE D CD1 1 
ATOM   9838  N N   . ILE D 1 195 ? 44.901  -38.750 110.683 1.00 53.04  ? 214 ILE D N   1 
ATOM   9839  C CA  . ILE D 1 195 ? 45.889  -39.647 111.282 1.00 52.68  ? 214 ILE D CA  1 
ATOM   9840  C C   . ILE D 1 195 ? 46.816  -40.213 110.214 1.00 58.08  ? 214 ILE D C   1 
ATOM   9841  O O   . ILE D 1 195 ? 48.037  -40.286 110.417 1.00 57.19  ? 214 ILE D O   1 
ATOM   9842  C CB  . ILE D 1 195 ? 45.204  -40.754 112.087 1.00 52.36  ? 214 ILE D CB  1 
ATOM   9843  C CG1 . ILE D 1 195 ? 44.503  -40.137 113.287 1.00 45.48  ? 214 ILE D CG1 1 
ATOM   9844  C CG2 . ILE D 1 195 ? 46.224  -41.730 112.583 1.00 52.59  ? 214 ILE D CG2 1 
ATOM   9845  C CD1 . ILE D 1 195 ? 43.485  -41.003 113.900 1.00 44.14  ? 214 ILE D CD1 1 
ATOM   9846  N N   . GLN D 1 196 ? 46.257  -40.605 109.057 1.00 55.04  ? 215 GLN D N   1 
ATOM   9847  C CA  . GLN D 1 196 ? 47.079  -41.014 107.913 1.00 58.83  ? 215 GLN D CA  1 
ATOM   9848  C C   . GLN D 1 196 ? 47.961  -39.860 107.426 1.00 56.88  ? 215 GLN D C   1 
ATOM   9849  O O   . GLN D 1 196 ? 49.163  -40.037 107.182 1.00 57.64  ? 215 GLN D O   1 
ATOM   9850  C CB  . GLN D 1 196 ? 46.192  -41.545 106.783 1.00 62.01  ? 215 GLN D CB  1 
ATOM   9851  N N   . GLU D 1 197 ? 47.378  -38.656 107.284 1.00 61.44  ? 216 GLU D N   1 
ATOM   9852  C CA  . GLU D 1 197 ? 48.171  -37.503 106.849 1.00 60.00  ? 216 GLU D CA  1 
ATOM   9853  C C   . GLU D 1 197 ? 49.238  -37.170 107.884 1.00 56.42  ? 216 GLU D C   1 
ATOM   9854  O O   . GLU D 1 197 ? 50.340  -36.743 107.530 1.00 56.80  ? 216 GLU D O   1 
ATOM   9855  C CB  . GLU D 1 197 ? 47.276  -36.289 106.571 1.00 58.41  ? 216 GLU D CB  1 
ATOM   9856  N N   . THR D 1 198 ? 48.942  -37.408 109.163 1.00 60.98  ? 217 THR D N   1 
ATOM   9857  C CA  . THR D 1 198 ? 49.951  -37.241 110.206 1.00 57.57  ? 217 THR D CA  1 
ATOM   9858  C C   . THR D 1 198 ? 51.066  -38.271 110.084 1.00 60.54  ? 217 THR D C   1 
ATOM   9859  O O   . THR D 1 198 ? 52.244  -37.942 110.234 1.00 60.34  ? 217 THR D O   1 
ATOM   9860  C CB  . THR D 1 198 ? 49.298  -37.347 111.585 1.00 53.15  ? 217 THR D CB  1 
ATOM   9861  O OG1 . THR D 1 198 ? 48.433  -36.231 111.802 1.00 49.76  ? 217 THR D OG1 1 
ATOM   9862  C CG2 . THR D 1 198 ? 50.344  -37.409 112.678 1.00 49.99  ? 217 THR D CG2 1 
ATOM   9863  N N   . ARG D 1 199 ? 50.725  -39.527 109.832 1.00 53.57  ? 218 ARG D N   1 
ATOM   9864  C CA  . ARG D 1 199 ? 51.778  -40.530 109.695 1.00 56.92  ? 218 ARG D CA  1 
ATOM   9865  C C   . ARG D 1 199 ? 52.678  -40.234 108.499 1.00 59.78  ? 218 ARG D C   1 
ATOM   9866  O O   . ARG D 1 199 ? 53.884  -40.493 108.549 1.00 60.89  ? 218 ARG D O   1 
ATOM   9867  C CB  . ARG D 1 199 ? 51.156  -41.930 109.602 1.00 60.89  ? 218 ARG D CB  1 
ATOM   9868  C CG  . ARG D 1 199 ? 52.130  -43.044 109.291 1.00 64.39  ? 218 ARG D CG  1 
ATOM   9869  C CD  . ARG D 1 199 ? 53.271  -43.152 110.289 1.00 62.37  ? 218 ARG D CD  1 
ATOM   9870  N NE  . ARG D 1 199 ? 52.821  -43.416 111.646 1.00 60.04  ? 218 ARG D NE  1 
ATOM   9871  C CZ  . ARG D 1 199 ? 53.605  -43.341 112.711 1.00 56.11  ? 218 ARG D CZ  1 
ATOM   9872  N NH1 . ARG D 1 199 ? 54.874  -42.984 112.604 1.00 56.45  ? 218 ARG D NH1 1 
ATOM   9873  N NH2 . ARG D 1 199 ? 53.105  -43.631 113.911 1.00 52.17  ? 218 ARG D NH2 1 
ATOM   9874  N N   . GLN D 1 200 ? 52.123  -39.690 107.416 1.00 60.03  ? 219 GLN D N   1 
ATOM   9875  C CA  . GLN D 1 200 ? 52.954  -39.422 106.246 1.00 62.64  ? 219 GLN D CA  1 
ATOM   9876  C C   . GLN D 1 200 ? 53.836  -38.201 106.471 1.00 60.44  ? 219 GLN D C   1 
ATOM   9877  O O   . GLN D 1 200 ? 54.956  -38.159 105.961 1.00 63.15  ? 219 GLN D O   1 
ATOM   9878  C CB  . GLN D 1 200 ? 52.084  -39.259 104.990 1.00 64.48  ? 219 GLN D CB  1 
ATOM   9879  N N   . LYS D 1 201 ? 53.385  -37.245 107.288 1.00 63.91  ? 220 LYS D N   1 
ATOM   9880  C CA  . LYS D 1 201 ? 54.136  -36.006 107.465 1.00 63.10  ? 220 LYS D CA  1 
ATOM   9881  C C   . LYS D 1 201 ? 55.275  -36.144 108.478 1.00 62.66  ? 220 LYS D C   1 
ATOM   9882  O O   . LYS D 1 201 ? 56.374  -35.606 108.252 1.00 64.08  ? 220 LYS D O   1 
ATOM   9883  C CB  . LYS D 1 201 ? 53.187  -34.880 107.897 1.00 59.70  ? 220 LYS D CB  1 
ATOM   9884  C CG  . LYS D 1 201 ? 52.112  -34.528 106.865 1.00 61.62  ? 220 LYS D CG  1 
ATOM   9885  C CD  . LYS D 1 201 ? 52.212  -33.079 106.414 1.00 62.90  ? 220 LYS D CD  1 
ATOM   9886  C CE  . LYS D 1 201 ? 51.176  -32.811 105.354 1.00 62.02  ? 220 LYS D CE  1 
ATOM   9887  N NZ  . LYS D 1 201 ? 50.731  -31.407 105.372 1.00 64.06  ? 220 LYS D NZ  1 
ATOM   9888  N N   . ILE D 1 202 ? 55.035  -36.824 109.607 1.00 63.51  ? 221 ILE D N   1 
ATOM   9889  C CA  . ILE D 1 202 ? 56.091  -37.031 110.599 1.00 63.49  ? 221 ILE D CA  1 
ATOM   9890  C C   . ILE D 1 202 ? 56.981  -38.220 110.273 1.00 67.54  ? 221 ILE D C   1 
ATOM   9891  O O   . ILE D 1 202 ? 58.046  -38.375 110.881 1.00 68.91  ? 221 ILE D O   1 
ATOM   9892  C CB  . ILE D 1 202 ? 55.489  -37.205 112.009 1.00 59.43  ? 221 ILE D CB  1 
ATOM   9893  C CG1 . ILE D 1 202 ? 54.733  -38.532 112.099 1.00 59.11  ? 221 ILE D CG1 1 
ATOM   9894  C CG2 . ILE D 1 202 ? 54.603  -36.004 112.326 1.00 56.12  ? 221 ILE D CG2 1 
ATOM   9895  C CD1 . ILE D 1 202 ? 54.010  -38.752 113.438 1.00 55.26  ? 221 ILE D CD1 1 
ATOM   9896  N N   . GLY D 1 203 ? 56.589  -39.056 109.327 1.00 68.34  ? 222 GLY D N   1 
ATOM   9897  C CA  . GLY D 1 203 ? 57.383  -40.202 108.949 1.00 70.99  ? 222 GLY D CA  1 
ATOM   9898  C C   . GLY D 1 203 ? 57.072  -41.425 109.789 1.00 65.48  ? 222 GLY D C   1 
ATOM   9899  O O   . GLY D 1 203 ? 56.352  -41.371 110.790 1.00 59.81  ? 222 GLY D O   1 
ATOM   9900  N N   . ASP D 1 204 ? 57.643  -42.570 109.359 1.00 68.52  ? 223 ASP D N   1 
ATOM   9901  C CA  . ASP D 1 204 ? 57.417  -43.861 110.010 1.00 65.06  ? 223 ASP D CA  1 
ATOM   9902  C C   . ASP D 1 204 ? 58.370  -44.143 111.176 1.00 63.77  ? 223 ASP D C   1 
ATOM   9903  O O   . ASP D 1 204 ? 58.163  -45.135 111.884 1.00 61.04  ? 223 ASP D O   1 
ATOM   9904  C CB  . ASP D 1 204 ? 57.516  -44.998 108.971 1.00 68.66  ? 223 ASP D CB  1 
ATOM   9905  N N   . ASP D 1 205 ? 59.393  -43.299 111.406 1.00 65.44  ? 224 ASP D N   1 
ATOM   9906  C CA  . ASP D 1 205 ? 60.332  -43.450 112.517 1.00 65.44  ? 224 ASP D CA  1 
ATOM   9907  C C   . ASP D 1 205 ? 59.973  -42.596 113.729 1.00 61.53  ? 224 ASP D C   1 
ATOM   9908  O O   . ASP D 1 205 ? 60.789  -42.483 114.645 1.00 62.43  ? 224 ASP D O   1 
ATOM   9909  C CB  . ASP D 1 205 ? 61.751  -43.101 112.064 1.00 72.24  ? 224 ASP D CB  1 
ATOM   9910  N N   . LYS D 1 206 ? 58.778  -41.995 113.750 1.00 61.12  ? 225 LYS D N   1 
ATOM   9911  C CA  . LYS D 1 206 ? 58.289  -41.123 114.820 1.00 58.53  ? 225 LYS D CA  1 
ATOM   9912  C C   . LYS D 1 206 ? 57.104  -41.795 115.504 1.00 56.05  ? 225 LYS D C   1 
ATOM   9913  O O   . LYS D 1 206 ? 56.523  -42.754 114.992 1.00 56.87  ? 225 LYS D O   1 
ATOM   9914  C CB  . LYS D 1 206 ? 57.902  -39.737 114.273 1.00 59.53  ? 225 LYS D CB  1 
ATOM   9915  N N   . LEU D 1 207 ? 56.736  -41.282 116.672 1.00 55.94  ? 226 LEU D N   1 
ATOM   9916  C CA  . LEU D 1 207 ? 55.652  -41.857 117.462 1.00 53.46  ? 226 LEU D CA  1 
ATOM   9917  C C   . LEU D 1 207 ? 54.362  -41.051 117.352 1.00 51.99  ? 226 LEU D C   1 
ATOM   9918  O O   . LEU D 1 207 ? 54.385  -39.823 117.333 1.00 52.12  ? 226 LEU D O   1 
ATOM   9919  C CB  . LEU D 1 207 ? 56.056  -41.924 118.931 1.00 52.16  ? 226 LEU D CB  1 
ATOM   9920  C CG  . LEU D 1 207 ? 57.203  -42.888 119.232 1.00 53.47  ? 226 LEU D CG  1 
ATOM   9921  C CD1 . LEU D 1 207 ? 57.911  -42.468 120.533 1.00 53.06  ? 226 LEU D CD1 1 
ATOM   9922  C CD2 . LEU D 1 207 ? 56.624  -44.302 119.267 1.00 53.43  ? 226 LEU D CD2 1 
ATOM   9923  N N   . ILE D 1 208 ? 53.228  -41.747 117.301 1.00 51.18  ? 227 ILE D N   1 
ATOM   9924  C CA  . ILE D 1 208 ? 51.910  -41.107 117.376 1.00 49.59  ? 227 ILE D CA  1 
ATOM   9925  C C   . ILE D 1 208 ? 51.213  -41.655 118.613 1.00 47.41  ? 227 ILE D C   1 
ATOM   9926  O O   . ILE D 1 208 ? 50.843  -42.835 118.658 1.00 47.54  ? 227 ILE D O   1 
ATOM   9927  C CB  . ILE D 1 208 ? 51.052  -41.342 116.124 1.00 50.83  ? 227 ILE D CB  1 
ATOM   9928  C CG1 . ILE D 1 208 ? 51.648  -40.582 114.944 1.00 53.13  ? 227 ILE D CG1 1 
ATOM   9929  C CG2 . ILE D 1 208 ? 49.621  -40.878 116.352 1.00 49.48  ? 227 ILE D CG2 1 
ATOM   9930  C CD1 . ILE D 1 208 ? 50.916  -40.801 113.664 1.00 54.51  ? 227 ILE D CD1 1 
ATOM   9931  N N   . VAL D 1 209 ? 51.047  -40.809 119.611 1.00 46.58  ? 228 VAL D N   1 
ATOM   9932  C CA  . VAL D 1 209 ? 50.271  -41.105 120.811 1.00 44.66  ? 228 VAL D CA  1 
ATOM   9933  C C   . VAL D 1 209 ? 48.953  -40.364 120.674 1.00 43.61  ? 228 VAL D C   1 
ATOM   9934  O O   . VAL D 1 209 ? 48.915  -39.221 120.200 1.00 44.27  ? 228 VAL D O   1 
ATOM   9935  C CB  . VAL D 1 209 ? 51.022  -40.674 122.089 1.00 44.23  ? 228 VAL D CB  1 
ATOM   9936  C CG1 . VAL D 1 209 ? 50.362  -41.291 123.331 1.00 42.38  ? 228 VAL D CG1 1 
ATOM   9937  C CG2 . VAL D 1 209 ? 52.491  -41.055 122.012 1.00 45.95  ? 228 VAL D CG2 1 
ATOM   9938  N N   . TYR D 1 210 ? 47.864  -41.010 121.062 1.00 40.91  ? 229 TYR D N   1 
ATOM   9939  C CA  . TYR D 1 210 ? 46.553  -40.398 120.966 1.00 39.82  ? 229 TYR D CA  1 
ATOM   9940  C C   . TYR D 1 210 ? 45.760  -40.729 122.207 1.00 37.87  ? 229 TYR D C   1 
ATOM   9941  O O   . TYR D 1 210 ? 46.093  -41.638 122.964 1.00 37.88  ? 229 TYR D O   1 
ATOM   9942  C CB  . TYR D 1 210 ? 45.791  -40.834 119.709 1.00 40.99  ? 229 TYR D CB  1 
ATOM   9943  C CG  . TYR D 1 210 ? 45.059  -42.154 119.759 1.00 40.75  ? 229 TYR D CG  1 
ATOM   9944  C CD1 . TYR D 1 210 ? 45.692  -43.341 119.366 1.00 42.39  ? 229 TYR D CD1 1 
ATOM   9945  C CD2 . TYR D 1 210 ? 43.728  -42.229 120.145 1.00 39.78  ? 229 TYR D CD2 1 
ATOM   9946  C CE1 . TYR D 1 210 ? 45.034  -44.541 119.370 1.00 43.00  ? 229 TYR D CE1 1 
ATOM   9947  C CE2 . TYR D 1 210 ? 43.075  -43.447 120.171 1.00 40.19  ? 229 TYR D CE2 1 
ATOM   9948  C CZ  . TYR D 1 210 ? 43.731  -44.592 119.769 1.00 41.91  ? 229 TYR D CZ  1 
ATOM   9949  O OH  . TYR D 1 210 ? 43.073  -45.799 119.764 1.00 43.07  ? 229 TYR D OH  1 
ATOM   9950  N N   . ASN D 1 211 ? 44.715  -39.963 122.406 1.00 40.07  ? 230 ASN D N   1 
ATOM   9951  C CA  . ASN D 1 211 ? 43.800  -40.110 123.529 1.00 38.65  ? 230 ASN D CA  1 
ATOM   9952  C C   . ASN D 1 211 ? 42.426  -40.344 122.909 1.00 38.88  ? 230 ASN D C   1 
ATOM   9953  O O   . ASN D 1 211 ? 41.773  -39.389 122.446 1.00 39.21  ? 230 ASN D O   1 
ATOM   9954  C CB  . ASN D 1 211 ? 43.809  -38.868 124.427 1.00 38.06  ? 230 ASN D CB  1 
ATOM   9955  C CG  . ASN D 1 211 ? 42.957  -39.057 125.657 1.00 37.36  ? 230 ASN D CG  1 
ATOM   9956  O OD1 . ASN D 1 211 ? 42.612  -40.194 126.007 1.00 37.68  ? 230 ASN D OD1 1 
ATOM   9957  N ND2 . ASN D 1 211 ? 42.601  -37.977 126.310 1.00 37.38  ? 230 ASN D ND2 1 
ATOM   9958  N N   . GLY D 1 212 ? 41.975  -41.594 122.897 1.00 37.69  ? 231 GLY D N   1 
ATOM   9959  C CA  . GLY D 1 212 ? 42.606  -42.776 123.425 1.00 37.67  ? 231 GLY D CA  1 
ATOM   9960  C C   . GLY D 1 212 ? 41.571  -43.848 123.749 1.00 37.65  ? 231 GLY D C   1 
ATOM   9961  O O   . GLY D 1 212 ? 40.454  -43.851 123.207 1.00 38.44  ? 231 GLY D O   1 
ATOM   9962  N N   . ILE D 1 213 ? 41.950  -44.772 124.632 1.00 35.57  ? 232 ILE D N   1 
ATOM   9963  C CA  . ILE D 1 213 ? 41.050  -45.826 125.100 1.00 35.40  ? 232 ILE D CA  1 
ATOM   9964  C C   . ILE D 1 213 ? 40.135  -45.244 126.170 1.00 34.43  ? 232 ILE D C   1 
ATOM   9965  O O   . ILE D 1 213 ? 40.602  -44.568 127.099 1.00 33.89  ? 232 ILE D O   1 
ATOM   9966  C CB  . ILE D 1 213 ? 41.865  -47.027 125.635 1.00 35.79  ? 232 ILE D CB  1 
ATOM   9967  C CG1 . ILE D 1 213 ? 42.631  -47.682 124.479 1.00 37.83  ? 232 ILE D CG1 1 
ATOM   9968  C CG2 . ILE D 1 213 ? 40.982  -47.952 126.346 1.00 35.87  ? 232 ILE D CG2 1 
ATOM   9969  C CD1 . ILE D 1 213 ? 43.970  -48.324 124.888 1.00 38.64  ? 232 ILE D CD1 1 
ATOM   9970  N N   . ARG D 1 214 ? 38.837  -45.501 126.053 1.00 33.27  ? 233 ARG D N   1 
ATOM   9971  C CA  . ARG D 1 214 ? 37.854  -44.928 126.961 1.00 33.40  ? 233 ARG D CA  1 
ATOM   9972  C C   . ARG D 1 214 ? 36.649  -45.841 127.072 1.00 34.16  ? 233 ARG D C   1 
ATOM   9973  O O   . ARG D 1 214 ? 36.033  -46.176 126.057 1.00 34.90  ? 233 ARG D O   1 
ATOM   9974  C CB  . ARG D 1 214 ? 37.366  -43.549 126.483 1.00 33.82  ? 233 ARG D CB  1 
ATOM   9975  C CG  . ARG D 1 214 ? 36.272  -42.934 127.354 1.00 34.94  ? 233 ARG D CG  1 
ATOM   9976  C CD  . ARG D 1 214 ? 36.815  -42.361 128.670 1.00 35.03  ? 233 ARG D CD  1 
ATOM   9977  N NE  . ARG D 1 214 ? 37.992  -41.518 128.460 1.00 34.15  ? 233 ARG D NE  1 
ATOM   9978  C CZ  . ARG D 1 214 ? 37.966  -40.286 127.977 1.00 34.43  ? 233 ARG D CZ  1 
ATOM   9979  N NH1 . ARG D 1 214 ? 36.831  -39.619 127.842 1.00 35.15  ? 233 ARG D NH1 1 
ATOM   9980  N NH2 . ARG D 1 214 ? 39.101  -39.731 127.583 1.00 34.16  ? 233 ARG D NH2 1 
ATOM   9981  N N   . SER D 1 215 ? 36.286  -46.201 128.293 1.00 33.14  ? 234 SER D N   1 
ATOM   9982  C CA  . SER D 1 215 ? 35.191  -47.130 128.499 1.00 34.13  ? 234 SER D CA  1 
ATOM   9983  C C   . SER D 1 215 ? 34.204  -46.494 129.456 1.00 35.27  ? 234 SER D C   1 
ATOM   9984  O O   . SER D 1 215 ? 34.557  -46.190 130.594 1.00 35.95  ? 234 SER D O   1 
ATOM   9985  C CB  . SER D 1 215 ? 35.705  -48.490 129.038 1.00 34.80  ? 234 SER D CB  1 
ATOM   9986  O OG  . SER D 1 215 ? 36.543  -49.138 128.077 1.00 34.64  ? 234 SER D OG  1 
ATOM   9987  N N   . THR D 1 216 ? 32.979  -46.303 129.004 1.00 33.65  ? 235 THR D N   1 
ATOM   9988  C CA  . THR D 1 216 ? 31.911  -45.873 129.892 1.00 35.32  ? 235 THR D CA  1 
ATOM   9989  C C   . THR D 1 216 ? 30.785  -46.889 129.819 1.00 36.57  ? 235 THR D C   1 
ATOM   9990  O O   . THR D 1 216 ? 30.842  -47.860 129.035 1.00 36.64  ? 235 THR D O   1 
ATOM   9991  C CB  . THR D 1 216 ? 31.420  -44.464 129.530 1.00 35.53  ? 235 THR D CB  1 
ATOM   9992  O OG1 . THR D 1 216 ? 30.672  -44.492 128.305 1.00 35.99  ? 235 THR D OG1 1 
ATOM   9993  C CG2 . THR D 1 216 ? 32.634  -43.522 129.386 1.00 34.71  ? 235 THR D CG2 1 
ATOM   9994  N N   . PRO D 1 217 ? 29.776  -46.745 130.667 1.00 35.80  ? 236 PRO D N   1 
ATOM   9995  C CA  . PRO D 1 217 ? 28.693  -47.742 130.699 1.00 37.33  ? 236 PRO D CA  1 
ATOM   9996  C C   . PRO D 1 217 ? 27.971  -47.904 129.370 1.00 38.32  ? 236 PRO D C   1 
ATOM   9997  O O   . PRO D 1 217 ? 27.399  -48.966 129.081 1.00 39.42  ? 236 PRO D O   1 
ATOM   9998  C CB  . PRO D 1 217 ? 27.766  -47.189 131.791 1.00 38.59  ? 236 PRO D CB  1 
ATOM   9999  C CG  . PRO D 1 217 ? 28.725  -46.385 132.692 1.00 38.65  ? 236 PRO D CG  1 
ATOM   10000 C CD  . PRO D 1 217 ? 29.678  -45.750 131.745 1.00 36.84  ? 236 PRO D CD  1 
ATOM   10001 N N   . ASP D 1 218 ? 28.005  -46.877 128.547 1.00 40.56  ? 237 ASP D N   1 
ATOM   10002 C CA  . ASP D 1 218 ? 27.213  -46.797 127.344 1.00 41.85  ? 237 ASP D CA  1 
ATOM   10003 C C   . ASP D 1 218 ? 28.077  -46.858 126.109 1.00 41.22  ? 237 ASP D C   1 
ATOM   10004 O O   . ASP D 1 218 ? 27.552  -47.032 125.007 1.00 42.17  ? 237 ASP D O   1 
ATOM   10005 C CB  . ASP D 1 218 ? 26.391  -45.501 127.368 1.00 43.15  ? 237 ASP D CB  1 
ATOM   10006 C CG  . ASP D 1 218 ? 25.313  -45.508 128.493 1.00 45.36  ? 237 ASP D CG  1 
ATOM   10007 O OD1 . ASP D 1 218 ? 24.410  -46.394 128.462 1.00 46.83  ? 237 ASP D OD1 1 
ATOM   10008 O OD2 . ASP D 1 218 ? 25.386  -44.668 129.435 1.00 45.81  ? 237 ASP D OD2 1 
ATOM   10009 N N   . TRP D 1 219 ? 29.383  -46.768 126.255 1.00 37.95  ? 238 TRP D N   1 
ATOM   10010 C CA  . TRP D 1 219 ? 30.206  -46.777 125.074 1.00 36.99  ? 238 TRP D CA  1 
ATOM   10011 C C   . TRP D 1 219 ? 31.567  -47.294 125.454 1.00 35.68  ? 238 TRP D C   1 
ATOM   10012 O O   . TRP D 1 219 ? 32.016  -47.116 126.578 1.00 35.46  ? 238 TRP D O   1 
ATOM   10013 C CB  . TRP D 1 219 ? 30.339  -45.388 124.472 1.00 37.06  ? 238 TRP D CB  1 
ATOM   10014 C CG  . TRP D 1 219 ? 30.814  -45.401 123.058 1.00 37.12  ? 238 TRP D CG  1 
ATOM   10015 C CD1 . TRP D 1 219 ? 32.133  -45.468 122.639 1.00 36.30  ? 238 TRP D CD1 1 
ATOM   10016 C CD2 . TRP D 1 219 ? 30.014  -45.349 121.867 1.00 38.37  ? 238 TRP D CD2 1 
ATOM   10017 N NE1 . TRP D 1 219 ? 32.190  -45.443 121.251 1.00 37.19  ? 238 TRP D NE1 1 
ATOM   10018 C CE2 . TRP D 1 219 ? 30.909  -45.375 120.761 1.00 38.26  ? 238 TRP D CE2 1 
ATOM   10019 C CE3 . TRP D 1 219 ? 28.635  -45.293 121.625 1.00 39.61  ? 238 TRP D CE3 1 
ATOM   10020 C CZ2 . TRP D 1 219 ? 30.464  -45.339 119.444 1.00 39.32  ? 238 TRP D CZ2 1 
ATOM   10021 C CZ3 . TRP D 1 219 ? 28.186  -45.237 120.303 1.00 40.66  ? 238 TRP D CZ3 1 
ATOM   10022 C CH2 . TRP D 1 219 ? 29.101  -45.253 119.234 1.00 40.59  ? 238 TRP D CH2 1 
ATOM   10023 N N   . SER D 1 220 ? 32.240  -47.933 124.527 1.00 37.45  ? 239 SER D N   1 
ATOM   10024 C CA  . SER D 1 220 ? 33.604  -48.259 124.874 1.00 36.41  ? 239 SER D CA  1 
ATOM   10025 C C   . SER D 1 220 ? 34.413  -48.218 123.592 1.00 35.76  ? 239 SER D C   1 
ATOM   10026 O O   . SER D 1 220 ? 33.994  -48.744 122.552 1.00 37.37  ? 239 SER D O   1 
ATOM   10027 C CB  . SER D 1 220 ? 33.677  -49.595 125.619 1.00 37.22  ? 239 SER D CB  1 
ATOM   10028 O OG  . SER D 1 220 ? 33.753  -50.700 124.783 1.00 38.43  ? 239 SER D OG  1 
ATOM   10029 N N   . ALA D 1 221 ? 35.541  -47.519 123.676 1.00 35.43  ? 240 ALA D N   1 
ATOM   10030 C CA  . ALA D 1 221 ? 36.442  -47.264 122.567 1.00 35.49  ? 240 ALA D CA  1 
ATOM   10031 C C   . ALA D 1 221 ? 37.793  -47.875 122.909 1.00 34.75  ? 240 ALA D C   1 
ATOM   10032 O O   . ALA D 1 221 ? 38.420  -47.485 123.900 1.00 33.69  ? 240 ALA D O   1 
ATOM   10033 C CB  . ALA D 1 221 ? 36.540  -45.757 122.333 1.00 35.66  ? 240 ALA D CB  1 
ATOM   10034 N N   . GLY D 1 222 ? 38.211  -48.879 122.134 1.00 36.69  ? 241 GLY D N   1 
ATOM   10035 C CA  . GLY D 1 222 ? 39.475  -49.539 122.351 1.00 37.06  ? 241 GLY D CA  1 
ATOM   10036 C C   . GLY D 1 222 ? 40.538  -48.983 121.423 1.00 37.93  ? 241 GLY D C   1 
ATOM   10037 O O   . GLY D 1 222 ? 40.303  -48.095 120.623 1.00 38.35  ? 241 GLY D O   1 
ATOM   10038 N N   . PHE D 1 223 ? 41.736  -49.525 121.540 1.00 38.93  ? 242 PHE D N   1 
ATOM   10039 C CA  . PHE D 1 223 ? 42.794  -49.104 120.629 1.00 40.12  ? 242 PHE D CA  1 
ATOM   10040 C C   . PHE D 1 223 ? 42.306  -49.213 119.196 1.00 42.09  ? 242 PHE D C   1 
ATOM   10041 O O   . PHE D 1 223 ? 41.971  -50.294 118.731 1.00 44.42  ? 242 PHE D O   1 
ATOM   10042 C CB  . PHE D 1 223 ? 44.027  -49.957 120.851 1.00 41.87  ? 242 PHE D CB  1 
ATOM   10043 C CG  . PHE D 1 223 ? 45.301  -49.259 120.547 1.00 42.19  ? 242 PHE D CG  1 
ATOM   10044 C CD1 . PHE D 1 223 ? 45.597  -48.870 119.261 1.00 44.25  ? 242 PHE D CD1 1 
ATOM   10045 C CD2 . PHE D 1 223 ? 46.215  -49.045 121.529 1.00 41.45  ? 242 PHE D CD2 1 
ATOM   10046 C CE1 . PHE D 1 223 ? 46.776  -48.256 118.965 1.00 45.10  ? 242 PHE D CE1 1 
ATOM   10047 C CE2 . PHE D 1 223 ? 47.392  -48.440 121.245 1.00 42.37  ? 242 PHE D CE2 1 
ATOM   10048 C CZ  . PHE D 1 223 ? 47.674  -48.025 119.955 1.00 43.96  ? 242 PHE D CZ  1 
ATOM   10049 N N   . ASP D 1 224 ? 42.188  -48.069 118.526 1.00 45.45  ? 243 ASP D N   1 
ATOM   10050 C CA  . ASP D 1 224 ? 41.740  -47.996 117.142 1.00 47.25  ? 243 ASP D CA  1 
ATOM   10051 C C   . ASP D 1 224 ? 42.804  -47.279 116.323 1.00 47.89  ? 243 ASP D C   1 
ATOM   10052 O O   . ASP D 1 224 ? 43.747  -46.712 116.862 1.00 47.56  ? 243 ASP D O   1 
ATOM   10053 C CB  . ASP D 1 224 ? 40.382  -47.296 117.021 1.00 47.47  ? 243 ASP D CB  1 
ATOM   10054 C CG  . ASP D 1 224 ? 39.782  -47.435 115.596 1.00 50.62  ? 243 ASP D CG  1 
ATOM   10055 O OD1 . ASP D 1 224 ? 38.692  -46.849 115.282 1.00 51.60  ? 243 ASP D OD1 1 
ATOM   10056 O OD2 . ASP D 1 224 ? 40.426  -48.121 114.752 1.00 52.26  ? 243 ASP D OD2 1 
ATOM   10057 N N   . PHE D 1 225 ? 42.652  -47.315 115.004 1.00 48.70  ? 244 PHE D N   1 
ATOM   10058 C CA  . PHE D 1 225 ? 43.537  -46.625 114.064 1.00 50.05  ? 244 PHE D CA  1 
ATOM   10059 C C   . PHE D 1 225 ? 44.920  -47.259 114.011 1.00 51.31  ? 244 PHE D C   1 
ATOM   10060 O O   . PHE D 1 225 ? 45.890  -46.625 113.537 1.00 51.86  ? 244 PHE D O   1 
ATOM   10061 C CB  . PHE D 1 225 ? 43.648  -45.114 114.388 1.00 48.88  ? 244 PHE D CB  1 
ATOM   10062 C CG  . PHE D 1 225 ? 42.317  -44.450 114.630 1.00 47.54  ? 244 PHE D CG  1 
ATOM   10063 C CD1 . PHE D 1 225 ? 41.481  -44.152 113.579 1.00 48.57  ? 244 PHE D CD1 1 
ATOM   10064 C CD2 . PHE D 1 225 ? 41.894  -44.197 115.919 1.00 45.74  ? 244 PHE D CD2 1 
ATOM   10065 C CE1 . PHE D 1 225 ? 40.270  -43.588 113.814 1.00 47.49  ? 244 PHE D CE1 1 
ATOM   10066 C CE2 . PHE D 1 225 ? 40.694  -43.639 116.158 1.00 44.67  ? 244 PHE D CE2 1 
ATOM   10067 C CZ  . PHE D 1 225 ? 39.870  -43.331 115.112 1.00 45.57  ? 244 PHE D CZ  1 
ATOM   10068 N N   . ALA D 1 226 ? 45.013  -48.514 114.461 1.00 49.00  ? 245 ALA D N   1 
ATOM   10069 C CA  . ALA D 1 226 ? 46.304  -49.132 114.713 1.00 49.95  ? 245 ALA D CA  1 
ATOM   10070 C C   . ALA D 1 226 ? 47.222  -49.070 113.510 1.00 52.15  ? 245 ALA D C   1 
ATOM   10071 O O   . ALA D 1 226 ? 48.442  -49.159 113.677 1.00 52.72  ? 245 ALA D O   1 
ATOM   10072 C CB  . ALA D 1 226 ? 46.090  -50.581 115.143 1.00 50.69  ? 245 ALA D CB  1 
ATOM   10073 N N   . GLU D 1 227 ? 46.667  -48.905 112.308 1.00 52.50  ? 246 GLU D N   1 
ATOM   10074 C CA  . GLU D 1 227 ? 47.501  -48.856 111.114 1.00 54.83  ? 246 GLU D CA  1 
ATOM   10075 C C   . GLU D 1 227 ? 48.552  -47.758 111.227 1.00 54.61  ? 246 GLU D C   1 
ATOM   10076 O O   . GLU D 1 227 ? 49.635  -47.870 110.636 1.00 56.66  ? 246 GLU D O   1 
ATOM   10077 C CB  . GLU D 1 227 ? 46.633  -48.645 109.863 1.00 56.24  ? 246 GLU D CB  1 
ATOM   10078 N N   . TYR D 1 228 ? 48.265  -46.702 111.992 1.00 55.56  ? 247 TYR D N   1 
ATOM   10079 C CA  . TYR D 1 228 ? 49.130  -45.534 111.978 1.00 55.39  ? 247 TYR D CA  1 
ATOM   10080 C C   . TYR D 1 228 ? 49.599  -45.133 113.359 1.00 53.12  ? 247 TYR D C   1 
ATOM   10081 O O   . TYR D 1 228 ? 50.706  -44.616 113.524 1.00 54.30  ? 247 TYR D O   1 
ATOM   10082 C CB  . TYR D 1 228 ? 48.381  -44.378 111.326 1.00 55.16  ? 247 TYR D CB  1 
ATOM   10083 C CG  . TYR D 1 228 ? 47.916  -44.705 109.924 1.00 57.20  ? 247 TYR D CG  1 
ATOM   10084 C CD1 . TYR D 1 228 ? 48.830  -45.091 108.956 1.00 60.19  ? 247 TYR D CD1 1 
ATOM   10085 C CD2 . TYR D 1 228 ? 46.577  -44.638 109.579 1.00 56.55  ? 247 TYR D CD2 1 
ATOM   10086 C CE1 . TYR D 1 228 ? 48.430  -45.400 107.685 1.00 62.30  ? 247 TYR D CE1 1 
ATOM   10087 C CE2 . TYR D 1 228 ? 46.167  -44.934 108.304 1.00 58.79  ? 247 TYR D CE2 1 
ATOM   10088 C CZ  . TYR D 1 228 ? 47.096  -45.318 107.357 1.00 61.43  ? 247 TYR D CZ  1 
ATOM   10089 O OH  . TYR D 1 228 ? 46.686  -45.615 106.076 1.00 64.03  ? 247 TYR D OH  1 
ATOM   10090 N N   . THR D 1 229 ? 48.766  -45.369 114.351 1.00 51.53  ? 248 THR D N   1 
ATOM   10091 C CA  . THR D 1 229 ? 49.088  -45.002 115.713 1.00 49.59  ? 248 THR D CA  1 
ATOM   10092 C C   . THR D 1 229 ? 49.965  -46.056 116.365 1.00 49.69  ? 248 THR D C   1 
ATOM   10093 O O   . THR D 1 229 ? 49.918  -47.245 116.020 1.00 51.33  ? 248 THR D O   1 
ATOM   10094 C CB  . THR D 1 229 ? 47.807  -44.817 116.518 1.00 47.86  ? 248 THR D CB  1 
ATOM   10095 O OG1 . THR D 1 229 ? 47.059  -46.039 116.587 1.00 48.42  ? 248 THR D OG1 1 
ATOM   10096 C CG2 . THR D 1 229 ? 46.941  -43.768 115.862 1.00 47.59  ? 248 THR D CG2 1 
ATOM   10097 N N   . ASP D 1 230 ? 50.766  -45.595 117.330 1.00 48.23  ? 249 ASP D N   1 
ATOM   10098 C CA  . ASP D 1 230 ? 51.645  -46.452 118.119 1.00 48.40  ? 249 ASP D CA  1 
ATOM   10099 C C   . ASP D 1 230 ? 51.217  -46.601 119.568 1.00 46.55  ? 249 ASP D C   1 
ATOM   10100 O O   . ASP D 1 230 ? 51.451  -47.649 120.164 1.00 46.55  ? 249 ASP D O   1 
ATOM   10101 C CB  . ASP D 1 230 ? 53.072  -45.897 118.080 1.00 49.66  ? 249 ASP D CB  1 
ATOM   10102 C CG  . ASP D 1 230 ? 53.560  -45.676 116.666 1.00 52.23  ? 249 ASP D CG  1 
ATOM   10103 O OD1 . ASP D 1 230 ? 53.572  -46.645 115.863 1.00 54.26  ? 249 ASP D OD1 1 
ATOM   10104 O OD2 . ASP D 1 230 ? 53.928  -44.534 116.344 1.00 52.56  ? 249 ASP D OD2 1 
ATOM   10105 N N   . ALA D 1 231 ? 50.572  -45.585 120.136 1.00 47.35  ? 250 ALA D N   1 
ATOM   10106 C CA  . ALA D 1 231 ? 50.322  -45.545 121.561 1.00 45.37  ? 250 ALA D CA  1 
ATOM   10107 C C   . ALA D 1 231 ? 48.964  -44.936 121.827 1.00 43.52  ? 250 ALA D C   1 
ATOM   10108 O O   . ALA D 1 231 ? 48.537  -44.007 121.129 1.00 43.76  ? 250 ALA D O   1 
ATOM   10109 C CB  . ALA D 1 231 ? 51.380  -44.708 122.286 1.00 45.43  ? 250 ALA D CB  1 
ATOM   10110 N N   . ALA D 1 232 ? 48.235  -45.490 122.799 1.00 42.72  ? 251 ALA D N   1 
ATOM   10111 C CA  . ALA D 1 232 ? 46.913  -44.963 123.206 1.00 41.12  ? 251 ALA D CA  1 
ATOM   10112 C C   . ALA D 1 232 ? 46.954  -44.724 124.712 1.00 39.80  ? 251 ALA D C   1 
ATOM   10113 O O   . ALA D 1 232 ? 47.720  -45.434 125.396 1.00 40.25  ? 251 ALA D O   1 
ATOM   10114 C CB  . ALA D 1 232 ? 45.810  -45.918 122.817 1.00 41.35  ? 251 ALA D CB  1 
ATOM   10115 N N   . MET D 1 233 ? 46.172  -43.765 125.208 1.00 42.51  ? 252 MET D N   1 
ATOM   10116 C CA  . MET D 1 233 ? 46.185  -43.408 126.648 1.00 40.89  ? 252 MET D CA  1 
ATOM   10117 C C   . MET D 1 233 ? 44.835  -43.738 127.289 1.00 39.97  ? 252 MET D C   1 
ATOM   10118 O O   . MET D 1 233 ? 43.814  -43.311 126.723 1.00 40.28  ? 252 MET D O   1 
ATOM   10119 C CB  . MET D 1 233 ? 46.467  -41.911 126.835 1.00 40.88  ? 252 MET D CB  1 
ATOM   10120 C CG  . MET D 1 233 ? 46.062  -41.369 128.197 1.00 40.77  ? 252 MET D CG  1 
ATOM   10121 S SD  . MET D 1 233 ? 46.751  -39.745 128.579 1.00 40.76  ? 252 MET D SD  1 
ATOM   10122 C CE  . MET D 1 233 ? 48.502  -40.137 128.699 1.00 42.66  ? 252 MET D CE  1 
ATOM   10123 N N   . ILE D 1 234 ? 44.827  -44.494 128.388 1.00 35.39  ? 253 ILE D N   1 
ATOM   10124 C CA  . ILE D 1 234 ? 43.585  -44.732 129.179 1.00 34.65  ? 253 ILE D CA  1 
ATOM   10125 C C   . ILE D 1 234 ? 43.556  -43.529 130.125 1.00 34.34  ? 253 ILE D C   1 
ATOM   10126 O O   . ILE D 1 234 ? 43.982  -43.689 131.287 1.00 34.74  ? 253 ILE D O   1 
ATOM   10127 C CB  . ILE D 1 234 ? 43.608  -46.089 129.906 1.00 35.05  ? 253 ILE D CB  1 
ATOM   10128 C CG1 . ILE D 1 234 ? 43.942  -47.242 128.955 1.00 36.06  ? 253 ILE D CG1 1 
ATOM   10129 C CG2 . ILE D 1 234 ? 42.290  -46.333 130.644 1.00 35.70  ? 253 ILE D CG2 1 
ATOM   10130 C CD1 . ILE D 1 234 ? 44.289  -48.541 129.659 1.00 36.66  ? 253 ILE D CD1 1 
ATOM   10131 N N   . GLU D 1 235 ? 43.112  -42.361 129.652 1.00 36.11  ? 254 GLU D N   1 
ATOM   10132 C CA  . GLU D 1 235 ? 43.217  -41.130 130.427 1.00 36.12  ? 254 GLU D CA  1 
ATOM   10133 C C   . GLU D 1 235 ? 42.426  -41.221 131.726 1.00 36.64  ? 254 GLU D C   1 
ATOM   10134 O O   . GLU D 1 235 ? 42.835  -40.649 132.736 1.00 37.38  ? 254 GLU D O   1 
ATOM   10135 C CB  . GLU D 1 235 ? 42.737  -39.926 129.582 1.00 36.42  ? 254 GLU D CB  1 
ATOM   10136 C CG  . GLU D 1 235 ? 43.178  -38.590 130.184 1.00 37.20  ? 254 GLU D CG  1 
ATOM   10137 C CD  . GLU D 1 235 ? 42.284  -37.351 129.926 1.00 37.79  ? 254 GLU D CD  1 
ATOM   10138 O OE1 . GLU D 1 235 ? 41.465  -37.244 128.945 1.00 37.66  ? 254 GLU D OE1 1 
ATOM   10139 O OE2 . GLU D 1 235 ? 42.457  -36.429 130.739 1.00 38.57  ? 254 GLU D OE2 1 
ATOM   10140 N N   . HIS D 1 236 ? 41.311  -41.952 131.727 1.00 34.05  ? 255 HIS D N   1 
ATOM   10141 C CA  . HIS D 1 236 ? 40.349  -41.928 132.824 1.00 35.24  ? 255 HIS D CA  1 
ATOM   10142 C C   . HIS D 1 236 ? 40.275  -43.248 133.622 1.00 36.28  ? 255 HIS D C   1 
ATOM   10143 O O   . HIS D 1 236 ? 39.246  -43.546 134.227 1.00 38.02  ? 255 HIS D O   1 
ATOM   10144 C CB  . HIS D 1 236 ? 38.948  -41.586 132.283 1.00 35.96  ? 255 HIS D CB  1 
ATOM   10145 C CG  . HIS D 1 236 ? 38.758  -40.164 131.841 1.00 35.99  ? 255 HIS D CG  1 
ATOM   10146 N ND1 . HIS D 1 236 ? 37.530  -39.673 131.455 1.00 36.63  ? 255 HIS D ND1 1 
ATOM   10147 C CD2 . HIS D 1 236 ? 39.619  -39.120 131.747 1.00 35.76  ? 255 HIS D CD2 1 
ATOM   10148 C CE1 . HIS D 1 236 ? 37.645  -38.407 131.108 1.00 36.56  ? 255 HIS D CE1 1 
ATOM   10149 N NE2 . HIS D 1 236 ? 38.900  -38.042 131.294 1.00 36.43  ? 255 HIS D NE2 1 
ATOM   10150 N N   . PHE D 1 237 ? 41.352  -44.019 133.689 1.00 35.50  ? 256 PHE D N   1 
ATOM   10151 C CA  . PHE D 1 237 ? 41.262  -45.286 134.418 1.00 36.18  ? 256 PHE D CA  1 
ATOM   10152 C C   . PHE D 1 237 ? 40.739  -45.077 135.841 1.00 38.24  ? 256 PHE D C   1 
ATOM   10153 O O   . PHE D 1 237 ? 41.220  -44.210 136.576 1.00 38.65  ? 256 PHE D O   1 
ATOM   10154 C CB  . PHE D 1 237 ? 42.597  -46.043 134.491 1.00 35.65  ? 256 PHE D CB  1 
ATOM   10155 C CG  . PHE D 1 237 ? 42.429  -47.383 135.148 1.00 36.73  ? 256 PHE D CG  1 
ATOM   10156 C CD1 . PHE D 1 237 ? 41.876  -48.448 134.443 1.00 36.98  ? 256 PHE D CD1 1 
ATOM   10157 C CD2 . PHE D 1 237 ? 42.713  -47.564 136.499 1.00 38.16  ? 256 PHE D CD2 1 
ATOM   10158 C CE1 . PHE D 1 237 ? 41.655  -49.651 135.058 1.00 37.93  ? 256 PHE D CE1 1 
ATOM   10159 C CE2 . PHE D 1 237 ? 42.480  -48.764 137.101 1.00 39.52  ? 256 PHE D CE2 1 
ATOM   10160 C CZ  . PHE D 1 237 ? 41.943  -49.794 136.384 1.00 39.12  ? 256 PHE D CZ  1 
ATOM   10161 N N   . GLY D 1 238 ? 39.730  -45.862 136.210 1.00 37.74  ? 257 GLY D N   1 
ATOM   10162 C CA  . GLY D 1 238 ? 39.202  -45.850 137.562 1.00 40.21  ? 257 GLY D CA  1 
ATOM   10163 C C   . GLY D 1 238 ? 38.609  -44.547 138.029 1.00 41.24  ? 257 GLY D C   1 
ATOM   10164 O O   . GLY D 1 238 ? 38.501  -44.330 139.241 1.00 43.56  ? 257 GLY D O   1 
ATOM   10165 N N   . HIS D 1 239 ? 38.176  -43.686 137.106 1.00 42.43  ? 258 HIS D N   1 
ATOM   10166 C CA  . HIS D 1 239 ? 37.762  -42.329 137.452 1.00 43.31  ? 258 HIS D CA  1 
ATOM   10167 C C   . HIS D 1 239 ? 36.700  -41.832 136.485 1.00 42.74  ? 258 HIS D C   1 
ATOM   10168 O O   . HIS D 1 239 ? 36.431  -42.455 135.455 1.00 42.02  ? 258 HIS D O   1 
ATOM   10169 C CB  . HIS D 1 239 ? 38.960  -41.359 137.434 1.00 42.42  ? 258 HIS D CB  1 
ATOM   10170 C CG  . HIS D 1 239 ? 39.003  -40.437 138.606 1.00 43.88  ? 258 HIS D CG  1 
ATOM   10171 N ND1 . HIS D 1 239 ? 39.225  -40.883 139.895 1.00 45.58  ? 258 HIS D ND1 1 
ATOM   10172 C CD2 . HIS D 1 239 ? 38.830  -39.091 138.687 1.00 44.65  ? 258 HIS D CD2 1 
ATOM   10173 C CE1 . HIS D 1 239 ? 39.197  -39.844 140.718 1.00 46.76  ? 258 HIS D CE1 1 
ATOM   10174 N NE2 . HIS D 1 239 ? 38.940  -38.750 140.013 1.00 46.46  ? 258 HIS D NE2 1 
ATOM   10175 N N   . PHE D 1 240 ? 36.112  -40.687 136.830 1.00 41.74  ? 259 PHE D N   1 
ATOM   10176 C CA  . PHE D 1 240 ? 35.103  -40.000 136.017 1.00 41.20  ? 259 PHE D CA  1 
ATOM   10177 C C   . PHE D 1 240 ? 33.970  -40.977 135.728 1.00 42.46  ? 259 PHE D C   1 
ATOM   10178 O O   . PHE D 1 240 ? 33.401  -41.535 136.679 1.00 44.88  ? 259 PHE D O   1 
ATOM   10179 C CB  . PHE D 1 240 ? 35.808  -39.397 134.791 1.00 39.36  ? 259 PHE D CB  1 
ATOM   10180 C CG  . PHE D 1 240 ? 36.983  -38.536 135.145 1.00 38.91  ? 259 PHE D CG  1 
ATOM   10181 C CD1 . PHE D 1 240 ? 36.804  -37.357 135.849 1.00 39.92  ? 259 PHE D CD1 1 
ATOM   10182 C CD2 . PHE D 1 240 ? 38.275  -38.928 134.817 1.00 37.58  ? 259 PHE D CD2 1 
ATOM   10183 C CE1 . PHE D 1 240 ? 37.883  -36.591 136.202 1.00 39.71  ? 259 PHE D CE1 1 
ATOM   10184 C CE2 . PHE D 1 240 ? 39.362  -38.144 135.168 1.00 37.42  ? 259 PHE D CE2 1 
ATOM   10185 C CZ  . PHE D 1 240 ? 39.167  -36.986 135.866 1.00 38.61  ? 259 PHE D CZ  1 
ATOM   10186 N N   . GLN D 1 241 ? 33.596  -41.199 134.469 1.00 42.84  ? 260 GLN D N   1 
ATOM   10187 C CA  . GLN D 1 241 ? 32.547  -42.159 134.133 1.00 43.89  ? 260 GLN D CA  1 
ATOM   10188 C C   . GLN D 1 241 ? 33.084  -43.540 133.788 1.00 43.08  ? 260 GLN D C   1 
ATOM   10189 O O   . GLN D 1 241 ? 32.455  -44.256 133.008 1.00 42.78  ? 260 GLN D O   1 
ATOM   10190 C CB  . GLN D 1 241 ? 31.702  -41.649 132.967 1.00 44.00  ? 260 GLN D CB  1 
ATOM   10191 C CG  . GLN D 1 241 ? 31.332  -40.231 133.026 1.00 46.05  ? 260 GLN D CG  1 
ATOM   10192 C CD  . GLN D 1 241 ? 31.310  -39.636 131.604 1.00 46.31  ? 260 GLN D CD  1 
ATOM   10193 O OE1 . GLN D 1 241 ? 30.214  -39.394 131.033 1.00 45.04  ? 260 GLN D OE1 1 
ATOM   10194 N NE2 . GLN D 1 241 ? 32.519  -39.421 131.009 1.00 47.94  ? 260 GLN D NE2 1 
ATOM   10195 N N   . SER D 1 242 ? 34.251  -43.902 134.327 1.00 40.19  ? 261 SER D N   1 
ATOM   10196 C CA  . SER D 1 242 ? 34.952  -45.142 134.037 1.00 39.49  ? 261 SER D CA  1 
ATOM   10197 C C   . SER D 1 242 ? 35.371  -45.814 135.335 1.00 41.23  ? 261 SER D C   1 
ATOM   10198 O O   . SER D 1 242 ? 36.278  -46.659 135.338 1.00 41.12  ? 261 SER D O   1 
ATOM   10199 C CB  . SER D 1 242 ? 36.197  -44.896 133.184 1.00 37.50  ? 261 SER D CB  1 
ATOM   10200 O OG  . SER D 1 242 ? 35.857  -44.209 132.011 1.00 36.20  ? 261 SER D OG  1 
ATOM   10201 N N   . ALA D 1 243 ? 34.747  -45.435 136.437 1.00 38.79  ? 262 ALA D N   1 
ATOM   10202 C CA  . ALA D 1 243 ? 35.116  -45.983 137.737 1.00 40.86  ? 262 ALA D CA  1 
ATOM   10203 C C   . ALA D 1 243 ? 34.435  -47.312 138.044 1.00 42.27  ? 262 ALA D C   1 
ATOM   10204 O O   . ALA D 1 243 ? 34.812  -47.967 139.027 1.00 43.71  ? 262 ALA D O   1 
ATOM   10205 C CB  . ALA D 1 243 ? 34.788  -44.967 138.839 1.00 42.33  ? 262 ALA D CB  1 
ATOM   10206 N N   . SER D 1 244 ? 33.442  -47.708 137.243 1.00 39.19  ? 263 SER D N   1 
ATOM   10207 C CA  . SER D 1 244 ? 32.699  -48.931 137.481 1.00 39.67  ? 263 SER D CA  1 
ATOM   10208 C C   . SER D 1 244 ? 33.586  -50.133 137.201 1.00 38.96  ? 263 SER D C   1 
ATOM   10209 O O   . SER D 1 244 ? 34.571  -50.058 136.464 1.00 37.68  ? 263 SER D O   1 
ATOM   10210 C CB  . SER D 1 244 ? 31.437  -48.969 136.609 1.00 39.07  ? 263 SER D CB  1 
ATOM   10211 O OG  . SER D 1 244 ? 31.746  -49.296 135.271 1.00 37.50  ? 263 SER D OG  1 
ATOM   10212 N N   . LYS D 1 245 ? 33.211  -51.263 137.798 1.00 39.32  ? 264 LYS D N   1 
ATOM   10213 C CA  . LYS D 1 245 ? 34.012  -52.481 137.628 1.00 38.45  ? 264 LYS D CA  1 
ATOM   10214 C C   . LYS D 1 245 ? 33.959  -52.932 136.184 1.00 36.59  ? 264 LYS D C   1 
ATOM   10215 O O   . LYS D 1 245 ? 34.975  -53.377 135.633 1.00 35.05  ? 264 LYS D O   1 
ATOM   10216 C CB  . LYS D 1 245 ? 33.544  -53.579 138.582 1.00 40.35  ? 264 LYS D CB  1 
ATOM   10217 C CG  . LYS D 1 245 ? 32.163  -54.038 138.320 1.00 41.30  ? 264 LYS D CG  1 
ATOM   10218 C CD  . LYS D 1 245 ? 31.636  -54.903 139.426 1.00 43.32  ? 264 LYS D CD  1 
ATOM   10219 C CE  . LYS D 1 245 ? 30.244  -55.360 139.054 1.00 44.48  ? 264 LYS D CE  1 
ATOM   10220 N NZ  . LYS D 1 245 ? 29.219  -54.751 139.941 1.00 46.60  ? 264 LYS D NZ  1 
ATOM   10221 N N   . GLU D 1 246 ? 32.812  -52.748 135.524 1.00 38.35  ? 265 GLU D N   1 
ATOM   10222 C CA  . GLU D 1 246 ? 32.728  -53.119 134.116 1.00 37.10  ? 265 GLU D CA  1 
ATOM   10223 C C   . GLU D 1 246 ? 33.724  -52.315 133.304 1.00 35.11  ? 265 GLU D C   1 
ATOM   10224 O O   . GLU D 1 246 ? 34.510  -52.872 132.531 1.00 34.01  ? 265 GLU D O   1 
ATOM   10225 C CB  . GLU D 1 246 ? 31.314  -52.905 133.593 1.00 37.80  ? 265 GLU D CB  1 
ATOM   10226 C CG  . GLU D 1 246 ? 30.278  -53.818 134.212 1.00 39.59  ? 265 GLU D CG  1 
ATOM   10227 C CD  . GLU D 1 246 ? 29.723  -53.295 135.530 1.00 41.57  ? 265 GLU D CD  1 
ATOM   10228 O OE1 . GLU D 1 246 ? 30.231  -52.270 136.080 1.00 41.65  ? 265 GLU D OE1 1 
ATOM   10229 O OE2 . GLU D 1 246 ? 28.769  -53.917 136.023 1.00 43.40  ? 265 GLU D OE2 1 
ATOM   10230 N N   . THR D 1 247 ? 33.733  -50.996 133.493 1.00 36.87  ? 266 THR D N   1 
ATOM   10231 C CA  . THR D 1 247 ? 34.607  -50.200 132.653 1.00 35.29  ? 266 THR D CA  1 
ATOM   10232 C C   . THR D 1 247 ? 36.056  -50.346 133.080 1.00 34.35  ? 266 THR D C   1 
ATOM   10233 O O   . THR D 1 247 ? 36.953  -50.260 132.238 1.00 33.00  ? 266 THR D O   1 
ATOM   10234 C CB  . THR D 1 247 ? 34.151  -48.742 132.627 1.00 35.93  ? 266 THR D CB  1 
ATOM   10235 O OG1 . THR D 1 247 ? 34.091  -48.203 133.943 1.00 37.49  ? 266 THR D OG1 1 
ATOM   10236 C CG2 . THR D 1 247 ? 32.785  -48.657 132.057 1.00 36.00  ? 266 THR D CG2 1 
ATOM   10237 N N   . MET D 1 248 ? 36.322  -50.617 134.354 1.00 35.60  ? 267 MET D N   1 
ATOM   10238 C CA  . MET D 1 248 ? 37.708  -50.842 134.731 1.00 34.67  ? 267 MET D CA  1 
ATOM   10239 C C   . MET D 1 248 ? 38.208  -52.135 134.120 1.00 33.89  ? 267 MET D C   1 
ATOM   10240 O O   . MET D 1 248 ? 39.320  -52.199 133.597 1.00 32.64  ? 267 MET D O   1 
ATOM   10241 C CB  . MET D 1 248 ? 37.869  -50.879 136.254 1.00 36.62  ? 267 MET D CB  1 
ATOM   10242 C CG  . MET D 1 248 ? 37.641  -49.516 136.967 1.00 38.24  ? 267 MET D CG  1 
ATOM   10243 S SD  . MET D 1 248 ? 38.208  -49.615 138.672 1.00 40.61  ? 267 MET D SD  1 
ATOM   10244 C CE  . MET D 1 248 ? 36.847  -50.430 139.510 1.00 42.71  ? 267 MET D CE  1 
ATOM   10245 N N   . LEU D 1 249 ? 37.380  -53.175 134.133 1.00 34.78  ? 268 LEU D N   1 
ATOM   10246 C CA  . LEU D 1 249 ? 37.791  -54.434 133.522 1.00 34.59  ? 268 LEU D CA  1 
ATOM   10247 C C   . LEU D 1 249 ? 37.996  -54.290 132.018 1.00 33.33  ? 268 LEU D C   1 
ATOM   10248 O O   . LEU D 1 249 ? 38.945  -54.865 131.457 1.00 33.20  ? 268 LEU D O   1 
ATOM   10249 C CB  . LEU D 1 249 ? 36.761  -55.508 133.852 1.00 35.93  ? 268 LEU D CB  1 
ATOM   10250 C CG  . LEU D 1 249 ? 36.997  -56.887 133.249 1.00 36.17  ? 268 LEU D CG  1 
ATOM   10251 C CD1 . LEU D 1 249 ? 38.368  -57.365 133.720 1.00 35.94  ? 268 LEU D CD1 1 
ATOM   10252 C CD2 . LEU D 1 249 ? 35.883  -57.871 133.635 1.00 37.78  ? 268 LEU D CD2 1 
ATOM   10253 N N   . ARG D 1 250 ? 37.130  -53.524 131.346 1.00 32.97  ? 269 ARG D N   1 
ATOM   10254 C CA  . ARG D 1 250 ? 37.296  -53.354 129.911 1.00 32.37  ? 269 ARG D CA  1 
ATOM   10255 C C   . ARG D 1 250 ? 38.575  -52.603 129.586 1.00 31.64  ? 269 ARG D C   1 
ATOM   10256 O O   . ARG D 1 250 ? 39.252  -52.936 128.613 1.00 31.77  ? 269 ARG D O   1 
ATOM   10257 C CB  . ARG D 1 250 ? 36.090  -52.636 129.315 1.00 32.86  ? 269 ARG D CB  1 
ATOM   10258 C CG  . ARG D 1 250 ? 34.836  -53.473 129.339 1.00 34.00  ? 269 ARG D CG  1 
ATOM   10259 C CD  . ARG D 1 250 ? 33.617  -52.682 128.977 1.00 34.60  ? 269 ARG D CD  1 
ATOM   10260 N NE  . ARG D 1 250 ? 32.415  -53.429 129.298 1.00 36.14  ? 269 ARG D NE  1 
ATOM   10261 C CZ  . ARG D 1 250 ? 31.247  -52.895 129.606 1.00 37.01  ? 269 ARG D CZ  1 
ATOM   10262 N NH1 . ARG D 1 250 ? 31.036  -51.604 129.480 1.00 36.88  ? 269 ARG D NH1 1 
ATOM   10263 N NH2 . ARG D 1 250 ? 30.280  -53.680 130.087 1.00 37.97  ? 269 ARG D NH2 1 
ATOM   10264 N N   . ASP D 1 251 ? 38.945  -51.614 130.408 1.00 35.94  ? 270 ASP D N   1 
ATOM   10265 C CA  . ASP D 1 251 ? 40.204  -50.895 130.209 1.00 35.01  ? 270 ASP D CA  1 
ATOM   10266 C C   . ASP D 1 251 ? 41.431  -51.809 130.418 1.00 35.13  ? 270 ASP D C   1 
ATOM   10267 O O   . ASP D 1 251 ? 42.346  -51.845 129.578 1.00 35.19  ? 270 ASP D O   1 
ATOM   10268 C CB  . ASP D 1 251 ? 40.267  -49.679 131.160 1.00 34.83  ? 270 ASP D CB  1 
ATOM   10269 C CG  . ASP D 1 251 ? 39.373  -48.431 130.697 1.00 34.63  ? 270 ASP D CG  1 
ATOM   10270 O OD1 . ASP D 1 251 ? 39.230  -47.456 131.540 1.00 35.09  ? 270 ASP D OD1 1 
ATOM   10271 O OD2 . ASP D 1 251 ? 38.854  -48.389 129.521 1.00 34.52  ? 270 ASP D OD2 1 
ATOM   10272 N N   . ILE D 1 252 ? 41.501  -52.512 131.557 1.00 33.05  ? 271 ILE D N   1 
ATOM   10273 C CA  . ILE D 1 252 ? 42.627  -53.419 131.818 1.00 33.38  ? 271 ILE D CA  1 
ATOM   10274 C C   . ILE D 1 252 ? 42.763  -54.458 130.700 1.00 34.44  ? 271 ILE D C   1 
ATOM   10275 O O   . ILE D 1 252 ? 43.870  -54.724 130.202 1.00 34.94  ? 271 ILE D O   1 
ATOM   10276 C CB  . ILE D 1 252 ? 42.438  -54.109 133.176 1.00 34.02  ? 271 ILE D CB  1 
ATOM   10277 C CG1 . ILE D 1 252 ? 42.432  -53.082 134.298 1.00 34.21  ? 271 ILE D CG1 1 
ATOM   10278 C CG2 . ILE D 1 252 ? 43.539  -55.133 133.468 1.00 34.37  ? 271 ILE D CG2 1 
ATOM   10279 C CD1 . ILE D 1 252 ? 41.822  -53.590 135.552 1.00 35.80  ? 271 ILE D CD1 1 
ATOM   10280 N N   . LEU D 1 253 ? 41.636  -55.037 130.259 1.00 33.22  ? 272 LEU D N   1 
ATOM   10281 C CA  . LEU D 1 253 ? 41.702  -56.019 129.184 1.00 33.97  ? 272 LEU D CA  1 
ATOM   10282 C C   . LEU D 1 253 ? 42.163  -55.400 127.876 1.00 34.30  ? 272 LEU D C   1 
ATOM   10283 O O   . LEU D 1 253 ? 42.845  -56.060 127.080 1.00 35.82  ? 272 LEU D O   1 
ATOM   10284 C CB  . LEU D 1 253 ? 40.347  -56.674 128.985 1.00 34.67  ? 272 LEU D CB  1 
ATOM   10285 C CG  . LEU D 1 253 ? 40.022  -57.690 130.095 1.00 35.17  ? 272 LEU D CG  1 
ATOM   10286 C CD1 . LEU D 1 253 ? 38.627  -58.265 129.841 1.00 35.87  ? 272 LEU D CD1 1 
ATOM   10287 C CD2 . LEU D 1 253 ? 41.076  -58.771 130.225 1.00 35.83  ? 272 LEU D CD2 1 
ATOM   10288 N N   . GLU D 1 254 ? 41.791  -54.141 127.617 1.00 34.44  ? 273 GLU D N   1 
ATOM   10289 C CA  . GLU D 1 254 ? 42.175  -53.534 126.349 1.00 35.49  ? 273 GLU D CA  1 
ATOM   10290 C C   . GLU D 1 254 ? 43.664  -53.242 126.334 1.00 35.79  ? 273 GLU D C   1 
ATOM   10291 O O   . GLU D 1 254 ? 44.321  -53.446 125.310 1.00 37.78  ? 273 GLU D O   1 
ATOM   10292 C CB  . GLU D 1 254 ? 41.338  -52.273 126.094 1.00 34.95  ? 273 GLU D CB  1 
ATOM   10293 C CG  . GLU D 1 254 ? 41.593  -51.587 124.763 1.00 36.16  ? 273 GLU D CG  1 
ATOM   10294 C CD  . GLU D 1 254 ? 41.367  -52.441 123.533 1.00 38.89  ? 273 GLU D CD  1 
ATOM   10295 O OE1 . GLU D 1 254 ? 41.068  -53.632 123.639 1.00 39.24  ? 273 GLU D OE1 1 
ATOM   10296 O OE2 . GLU D 1 254 ? 41.503  -51.924 122.412 1.00 40.80  ? 273 GLU D OE2 1 
ATOM   10297 N N   . MET D 1 255 ? 44.209  -52.771 127.462 1.00 38.11  ? 274 MET D N   1 
ATOM   10298 C CA  . MET D 1 255 ? 45.648  -52.655 127.614 1.00 38.68  ? 274 MET D CA  1 
ATOM   10299 C C   . MET D 1 255 ? 46.334  -53.986 127.305 1.00 40.16  ? 274 MET D C   1 
ATOM   10300 O O   . MET D 1 255 ? 47.261  -54.055 126.480 1.00 42.15  ? 274 MET D O   1 
ATOM   10301 C CB  . MET D 1 255 ? 45.961  -52.208 129.042 1.00 37.20  ? 274 MET D CB  1 
ATOM   10302 C CG  . MET D 1 255 ? 47.468  -52.017 129.266 1.00 37.80  ? 274 MET D CG  1 
ATOM   10303 S SD  . MET D 1 255 ? 47.977  -51.332 130.877 1.00 36.95  ? 274 MET D SD  1 
ATOM   10304 C CE  . MET D 1 255 ? 47.298  -52.617 131.964 1.00 36.59  ? 274 MET D CE  1 
ATOM   10305 N N   . GLN D 1 256 ? 45.880  -55.059 127.973 1.00 36.75  ? 275 GLN D N   1 
ATOM   10306 C CA  . GLN D 1 256 ? 46.436  -56.388 127.738 1.00 38.43  ? 275 GLN D CA  1 
ATOM   10307 C C   . GLN D 1 256 ? 46.408  -56.741 126.259 1.00 40.61  ? 275 GLN D C   1 
ATOM   10308 O O   . GLN D 1 256 ? 47.437  -57.093 125.679 1.00 42.54  ? 275 GLN D O   1 
ATOM   10309 C CB  . GLN D 1 256 ? 45.670  -57.422 128.567 1.00 38.25  ? 275 GLN D CB  1 
ATOM   10310 C CG  . GLN D 1 256 ? 46.178  -58.806 128.365 1.00 39.63  ? 275 GLN D CG  1 
ATOM   10311 C CD  . GLN D 1 256 ? 45.540  -59.846 129.279 1.00 39.74  ? 275 GLN D CD  1 
ATOM   10312 O OE1 . GLN D 1 256 ? 46.239  -60.549 130.001 1.00 40.15  ? 275 GLN D OE1 1 
ATOM   10313 N NE2 . GLN D 1 256 ? 44.227  -59.997 129.194 1.00 39.36  ? 275 GLN D NE2 1 
ATOM   10314 N N   . ARG D 1 257 ? 45.239  -56.625 125.623 1.00 36.95  ? 276 ARG D N   1 
ATOM   10315 C CA  . ARG D 1 257 ? 45.121  -57.023 124.218 1.00 39.40  ? 276 ARG D CA  1 
ATOM   10316 C C   . ARG D 1 257 ? 46.030  -56.180 123.330 1.00 41.19  ? 276 ARG D C   1 
ATOM   10317 O O   . ARG D 1 257 ? 46.767  -56.721 122.501 1.00 42.89  ? 276 ARG D O   1 
ATOM   10318 C CB  . ARG D 1 257 ? 43.671  -56.900 123.742 1.00 39.66  ? 276 ARG D CB  1 
ATOM   10319 C CG  . ARG D 1 257 ? 43.431  -57.474 122.343 1.00 41.82  ? 276 ARG D CG  1 
ATOM   10320 C CD  . ARG D 1 257 ? 42.101  -57.088 121.724 1.00 42.21  ? 276 ARG D CD  1 
ATOM   10321 N NE  . ARG D 1 257 ? 41.981  -55.633 121.503 1.00 42.78  ? 276 ARG D NE  1 
ATOM   10322 C CZ  . ARG D 1 257 ? 42.684  -54.934 120.614 1.00 44.52  ? 276 ARG D CZ  1 
ATOM   10323 N NH1 . ARG D 1 257 ? 43.633  -55.503 119.877 1.00 46.40  ? 276 ARG D NH1 1 
ATOM   10324 N NH2 . ARG D 1 257 ? 42.427  -53.638 120.461 1.00 43.79  ? 276 ARG D NH2 1 
ATOM   10325 N N   . ALA D 1 258 ? 46.014  -54.835 123.519 1.00 39.99  ? 277 ALA D N   1 
ATOM   10326 C CA  . ALA D 1 258 ? 46.714  -53.936 122.600 1.00 41.14  ? 277 ALA D CA  1 
ATOM   10327 C C   . ALA D 1 258 ? 48.217  -54.034 122.761 1.00 41.10  ? 277 ALA D C   1 
ATOM   10328 O O   . ALA D 1 258 ? 48.956  -53.997 121.770 1.00 42.97  ? 277 ALA D O   1 
ATOM   10329 C CB  . ALA D 1 258 ? 46.252  -52.497 122.806 1.00 39.76  ? 277 ALA D CB  1 
ATOM   10330 N N   . ALA D 1 259 ? 48.690  -54.157 123.998 1.00 40.46  ? 278 ALA D N   1 
ATOM   10331 C CA  . ALA D 1 259 ? 50.122  -54.294 124.218 1.00 41.24  ? 278 ALA D CA  1 
ATOM   10332 C C   . ALA D 1 259 ? 50.627  -55.632 123.709 1.00 43.43  ? 278 ALA D C   1 
ATOM   10333 O O   . ALA D 1 259 ? 51.701  -55.714 123.102 1.00 45.36  ? 278 ALA D O   1 
ATOM   10334 C CB  . ALA D 1 259 ? 50.423  -54.134 125.703 1.00 39.41  ? 278 ALA D CB  1 
ATOM   10335 N N   . LYS D 1 260 ? 49.858  -56.693 123.938 1.00 42.51  ? 279 LYS D N   1 
ATOM   10336 C CA  . LYS D 1 260 ? 50.157  -57.982 123.317 1.00 44.54  ? 279 LYS D CA  1 
ATOM   10337 C C   . LYS D 1 260 ? 50.140  -57.899 121.797 1.00 46.95  ? 279 LYS D C   1 
ATOM   10338 O O   . LYS D 1 260 ? 50.844  -58.659 121.124 1.00 49.11  ? 279 LYS D O   1 
ATOM   10339 C CB  . LYS D 1 260 ? 49.148  -59.034 123.773 1.00 44.63  ? 279 LYS D CB  1 
ATOM   10340 C CG  . LYS D 1 260 ? 49.597  -59.782 124.980 1.00 44.49  ? 279 LYS D CG  1 
ATOM   10341 C CD  . LYS D 1 260 ? 48.456  -60.569 125.603 1.00 44.52  ? 279 LYS D CD  1 
ATOM   10342 C CE  . LYS D 1 260 ? 49.059  -61.610 126.523 1.00 44.83  ? 279 LYS D CE  1 
ATOM   10343 N NZ  . LYS D 1 260 ? 47.964  -62.424 127.086 1.00 44.75  ? 279 LYS D NZ  1 
ATOM   10344 N N   . ALA D 1 261 ? 49.336  -57.007 121.237 1.00 42.45  ? 280 ALA D N   1 
ATOM   10345 C CA  . ALA D 1 261 ? 49.346  -56.787 119.797 1.00 43.58  ? 280 ALA D CA  1 
ATOM   10346 C C   . ALA D 1 261 ? 50.479  -55.870 119.340 1.00 42.99  ? 280 ALA D C   1 
ATOM   10347 O O   . ALA D 1 261 ? 50.520  -55.536 118.161 1.00 44.33  ? 280 ALA D O   1 
ATOM   10348 C CB  . ALA D 1 261 ? 48.004  -56.216 119.345 1.00 45.20  ? 280 ALA D CB  1 
ATOM   10349 N N   . GLY D 1 262 ? 51.382  -55.456 120.229 1.00 42.48  ? 281 GLY D N   1 
ATOM   10350 C CA  . GLY D 1 262 ? 52.558  -54.700 119.840 1.00 41.41  ? 281 GLY D CA  1 
ATOM   10351 C C   . GLY D 1 262 ? 52.439  -53.197 119.939 1.00 40.60  ? 281 GLY D C   1 
ATOM   10352 O O   . GLY D 1 262 ? 53.336  -52.482 119.471 1.00 40.65  ? 281 GLY D O   1 
ATOM   10353 N N   . LYS D 1 263 ? 51.369  -52.701 120.531 1.00 42.85  ? 282 LYS D N   1 
ATOM   10354 C CA  . LYS D 1 263 ? 51.188  -51.279 120.760 1.00 42.01  ? 282 LYS D CA  1 
ATOM   10355 C C   . LYS D 1 263 ? 51.663  -50.891 122.151 1.00 40.49  ? 282 LYS D C   1 
ATOM   10356 O O   . LYS D 1 263 ? 51.832  -51.740 123.040 1.00 40.23  ? 282 LYS D O   1 
ATOM   10357 C CB  . LYS D 1 263 ? 49.717  -50.901 120.622 1.00 43.18  ? 282 LYS D CB  1 
ATOM   10358 C CG  . LYS D 1 263 ? 49.145  -51.165 119.269 1.00 45.33  ? 282 LYS D CG  1 
ATOM   10359 C CD  . LYS D 1 263 ? 49.978  -50.510 118.179 1.00 44.92  ? 282 LYS D CD  1 
ATOM   10360 C CE  . LYS D 1 263 ? 49.235  -50.557 116.865 1.00 46.24  ? 282 LYS D CE  1 
ATOM   10361 N NZ  . LYS D 1 263 ? 50.155  -50.248 115.776 1.00 46.43  ? 282 LYS D NZ  1 
ATOM   10362 N N   . ILE D 1 264 ? 51.871  -49.577 122.325 1.00 43.56  ? 283 ILE D N   1 
ATOM   10363 C CA  . ILE D 1 264 ? 52.149  -48.930 123.602 1.00 42.20  ? 283 ILE D CA  1 
ATOM   10364 C C   . ILE D 1 264 ? 50.826  -48.555 124.240 1.00 42.33  ? 283 ILE D C   1 
ATOM   10365 O O   . ILE D 1 264 ? 49.924  -48.069 123.558 1.00 43.38  ? 283 ILE D O   1 
ATOM   10366 C CB  . ILE D 1 264 ? 53.027  -47.685 123.381 1.00 41.47  ? 283 ILE D CB  1 
ATOM   10367 C CG1 . ILE D 1 264 ? 54.371  -48.081 122.770 1.00 41.36  ? 283 ILE D CG1 1 
ATOM   10368 C CG2 . ILE D 1 264 ? 53.208  -46.885 124.674 1.00 40.70  ? 283 ILE D CG2 1 
ATOM   10369 C CD1 . ILE D 1 264 ? 55.117  -46.947 122.105 1.00 41.33  ? 283 ILE D CD1 1 
ATOM   10370 N N   . VAL D 1 265 ? 50.694  -48.793 125.540 1.00 40.03  ? 284 VAL D N   1 
ATOM   10371 C CA  . VAL D 1 265 ? 49.553  -48.323 126.314 1.00 40.33  ? 284 VAL D CA  1 
ATOM   10372 C C   . VAL D 1 265 ? 50.056  -47.542 127.527 1.00 39.34  ? 284 VAL D C   1 
ATOM   10373 O O   . VAL D 1 265 ? 51.021  -47.940 128.192 1.00 38.33  ? 284 VAL D O   1 
ATOM   10374 C CB  . VAL D 1 265 ? 48.666  -49.493 126.747 1.00 41.15  ? 284 VAL D CB  1 
ATOM   10375 C CG1 . VAL D 1 265 ? 47.473  -49.002 127.503 1.00 41.20  ? 284 VAL D CG1 1 
ATOM   10376 C CG2 . VAL D 1 265 ? 48.214  -50.272 125.552 1.00 42.84  ? 284 VAL D CG2 1 
ATOM   10377 N N   . VAL D 1 266 ? 49.420  -46.408 127.798 1.00 38.16  ? 285 VAL D N   1 
ATOM   10378 C CA  . VAL D 1 266 ? 49.749  -45.540 128.922 1.00 37.24  ? 285 VAL D CA  1 
ATOM   10379 C C   . VAL D 1 266 ? 48.499  -45.480 129.775 1.00 37.24  ? 285 VAL D C   1 
ATOM   10380 O O   . VAL D 1 266 ? 47.483  -44.931 129.328 1.00 37.73  ? 285 VAL D O   1 
ATOM   10381 C CB  . VAL D 1 266 ? 50.166  -44.128 128.463 1.00 37.18  ? 285 VAL D CB  1 
ATOM   10382 C CG1 . VAL D 1 266 ? 50.403  -43.190 129.680 1.00 36.53  ? 285 VAL D CG1 1 
ATOM   10383 C CG2 . VAL D 1 266 ? 51.414  -44.168 127.568 1.00 36.72  ? 285 VAL D CG2 1 
ATOM   10384 N N   . LEU D 1 267 ? 48.547  -46.047 130.980 1.00 34.19  ? 286 LEU D N   1 
ATOM   10385 C CA  . LEU D 1 267 ? 47.402  -46.038 131.898 1.00 34.90  ? 286 LEU D CA  1 
ATOM   10386 C C   . LEU D 1 267 ? 47.592  -44.906 132.904 1.00 34.81  ? 286 LEU D C   1 
ATOM   10387 O O   . LEU D 1 267 ? 48.575  -44.894 133.667 1.00 34.34  ? 286 LEU D O   1 
ATOM   10388 C CB  . LEU D 1 267 ? 47.243  -47.351 132.676 1.00 35.44  ? 286 LEU D CB  1 
ATOM   10389 C CG  . LEU D 1 267 ? 45.921  -47.552 133.427 1.00 37.18  ? 286 LEU D CG  1 
ATOM   10390 C CD1 . LEU D 1 267 ? 45.488  -49.048 133.394 1.00 38.20  ? 286 LEU D CD1 1 
ATOM   10391 C CD2 . LEU D 1 267 ? 45.955  -47.017 134.847 1.00 38.21  ? 286 LEU D CD2 1 
ATOM   10392 N N   . LYS D 1 268 ? 46.660  -43.953 132.916 1.00 35.74  ? 287 LYS D N   1 
ATOM   10393 C CA  . LYS D 1 268 ? 46.770  -42.803 133.798 1.00 36.18  ? 287 LYS D CA  1 
ATOM   10394 C C   . LYS D 1 268 ? 45.884  -43.052 135.022 1.00 38.58  ? 287 LYS D C   1 
ATOM   10395 O O   . LYS D 1 268 ? 44.648  -43.017 134.924 1.00 40.30  ? 287 LYS D O   1 
ATOM   10396 C CB  . LYS D 1 268 ? 46.416  -41.516 133.058 1.00 36.21  ? 287 LYS D CB  1 
ATOM   10397 C CG  . LYS D 1 268 ? 46.072  -40.345 133.980 1.00 38.61  ? 287 LYS D CG  1 
ATOM   10398 C CD  . LYS D 1 268 ? 47.178  -39.935 134.891 1.00 36.93  ? 287 LYS D CD  1 
ATOM   10399 C CE  . LYS D 1 268 ? 46.827  -38.616 135.556 1.00 38.95  ? 287 LYS D CE  1 
ATOM   10400 N NZ  . LYS D 1 268 ? 45.898  -38.806 136.710 1.00 39.86  ? 287 LYS D NZ  1 
ATOM   10401 N N   . GLY D 1 269 ? 46.537  -43.339 136.146 1.00 36.44  ? 288 GLY D N   1 
ATOM   10402 C CA  . GLY D 1 269 ? 45.835  -43.472 137.413 1.00 38.59  ? 288 GLY D CA  1 
ATOM   10403 C C   . GLY D 1 269 ? 45.559  -42.140 138.091 1.00 39.65  ? 288 GLY D C   1 
ATOM   10404 O O   . GLY D 1 269 ? 46.241  -41.140 137.873 1.00 38.39  ? 288 GLY D O   1 
ATOM   10405 N N   . TRP D 1 270 ? 44.526  -42.160 138.937 1.00 40.56  ? 289 TRP D N   1 
ATOM   10406 C CA  . TRP D 1 270 ? 44.040  -41.042 139.721 1.00 41.75  ? 289 TRP D CA  1 
ATOM   10407 C C   . TRP D 1 270 ? 43.923  -41.455 141.185 1.00 45.53  ? 289 TRP D C   1 
ATOM   10408 O O   . TRP D 1 270 ? 43.948  -42.639 141.542 1.00 44.75  ? 289 TRP D O   1 
ATOM   10409 C CB  . TRP D 1 270 ? 42.682  -40.568 139.179 1.00 42.96  ? 289 TRP D CB  1 
ATOM   10410 C CG  . TRP D 1 270 ? 42.761  -40.095 137.732 1.00 40.52  ? 289 TRP D CG  1 
ATOM   10411 C CD1 . TRP D 1 270 ? 42.703  -40.855 136.610 1.00 39.58  ? 289 TRP D CD1 1 
ATOM   10412 C CD2 . TRP D 1 270 ? 42.934  -38.759 137.291 1.00 40.13  ? 289 TRP D CD2 1 
ATOM   10413 N NE1 . TRP D 1 270 ? 42.847  -40.080 135.498 1.00 37.53  ? 289 TRP D NE1 1 
ATOM   10414 C CE2 . TRP D 1 270 ? 42.985  -38.782 135.889 1.00 38.48  ? 289 TRP D CE2 1 
ATOM   10415 C CE3 . TRP D 1 270 ? 43.073  -37.539 137.947 1.00 40.05  ? 289 TRP D CE3 1 
ATOM   10416 C CZ2 . TRP D 1 270 ? 43.133  -37.631 135.126 1.00 36.09  ? 289 TRP D CZ2 1 
ATOM   10417 C CZ3 . TRP D 1 270 ? 43.217  -36.401 137.187 1.00 38.62  ? 289 TRP D CZ3 1 
ATOM   10418 C CH2 . TRP D 1 270 ? 43.243  -36.459 135.789 1.00 37.04  ? 289 TRP D CH2 1 
ATOM   10419 N N   . ALA D 1 271 ? 43.794  -40.448 142.035 1.00 44.56  ? 290 ALA D N   1 
ATOM   10420 C CA  . ALA D 1 271 ? 43.641  -40.616 143.480 1.00 47.47  ? 290 ALA D CA  1 
ATOM   10421 C C   . ALA D 1 271 ? 42.159  -40.722 143.812 1.00 50.74  ? 290 ALA D C   1 
ATOM   10422 O O   . ALA D 1 271 ? 41.510  -39.730 144.172 1.00 53.95  ? 290 ALA D O   1 
ATOM   10423 C CB  . ALA D 1 271 ? 44.266  -39.441 144.231 1.00 46.04  ? 290 ALA D CB  1 
ATOM   10424 N N   . GLY D 1 272 ? 41.612  -41.917 143.690 1.00 48.16  ? 291 GLY D N   1 
ATOM   10425 C CA  . GLY D 1 272 ? 40.218  -42.166 143.996 1.00 52.94  ? 291 GLY D CA  1 
ATOM   10426 C C   . GLY D 1 272 ? 39.379  -42.550 142.776 1.00 53.03  ? 291 GLY D C   1 
ATOM   10427 O O   . GLY D 1 272 ? 39.883  -42.795 141.661 1.00 48.71  ? 291 GLY D O   1 
ATOM   10428 N N   . PHE D 1 273 ? 38.057  -42.606 143.007 1.00 51.72  ? 292 PHE D N   1 
ATOM   10429 C CA  . PHE D 1 273 ? 37.129  -43.005 141.943 1.00 52.48  ? 292 PHE D CA  1 
ATOM   10430 C C   . PHE D 1 273 ? 35.975  -42.039 141.690 1.00 53.64  ? 292 PHE D C   1 
ATOM   10431 O O   . PHE D 1 273 ? 35.346  -42.139 140.629 1.00 51.92  ? 292 PHE D O   1 
ATOM   10432 C CB  . PHE D 1 273 ? 36.529  -44.403 142.230 1.00 53.50  ? 292 PHE D CB  1 
ATOM   10433 C CG  . PHE D 1 273 ? 37.503  -45.354 142.854 1.00 53.96  ? 292 PHE D CG  1 
ATOM   10434 C CD1 . PHE D 1 273 ? 38.458  -46.011 142.072 1.00 51.07  ? 292 PHE D CD1 1 
ATOM   10435 C CD2 . PHE D 1 273 ? 37.480  -45.572 144.226 1.00 54.78  ? 292 PHE D CD2 1 
ATOM   10436 C CE1 . PHE D 1 273 ? 39.375  -46.881 142.668 1.00 50.35  ? 292 PHE D CE1 1 
ATOM   10437 C CE2 . PHE D 1 273 ? 38.386  -46.433 144.830 1.00 53.98  ? 292 PHE D CE2 1 
ATOM   10438 C CZ  . PHE D 1 273 ? 39.334  -47.094 144.059 1.00 51.84  ? 292 PHE D CZ  1 
ATOM   10439 N N   . THR D 1 274 ? 35.666  -41.121 142.598 1.00 55.03  ? 293 THR D N   1 
ATOM   10440 C CA  . THR D 1 274 ? 34.453  -40.329 142.459 1.00 56.36  ? 293 THR D CA  1 
ATOM   10441 C C   . THR D 1 274 ? 34.806  -38.857 142.537 1.00 55.97  ? 293 THR D C   1 
ATOM   10442 O O   . THR D 1 274 ? 35.977  -38.498 142.701 1.00 55.00  ? 293 THR D O   1 
ATOM   10443 C CB  . THR D 1 274 ? 33.420  -40.716 143.529 1.00 59.89  ? 293 THR D CB  1 
ATOM   10444 O OG1 . THR D 1 274 ? 33.779  -40.136 144.795 1.00 60.76  ? 293 THR D OG1 1 
ATOM   10445 C CG2 . THR D 1 274 ? 33.348  -42.231 143.640 1.00 60.31  ? 293 THR D CG2 1 
ATOM   10446 N N   . PHE D 1 275 ? 33.757  -38.019 142.388 1.00 57.01  ? 294 PHE D N   1 
ATOM   10447 C CA  . PHE D 1 275 ? 33.861  -36.567 142.467 1.00 57.06  ? 294 PHE D CA  1 
ATOM   10448 C C   . PHE D 1 275 ? 33.937  -36.069 143.913 1.00 59.91  ? 294 PHE D C   1 
ATOM   10449 O O   . PHE D 1 275 ? 34.313  -34.911 144.144 1.00 58.54  ? 294 PHE D O   1 
ATOM   10450 C CB  . PHE D 1 275 ? 32.649  -35.908 141.772 1.00 55.97  ? 294 PHE D CB  1 
ATOM   10451 N N   . ILE D 1 276 ? 33.549  -36.910 144.888 1.00 60.40  ? 295 ILE D N   1 
ATOM   10452 C CA  . ILE D 1 276 ? 33.691  -36.556 146.300 1.00 61.19  ? 295 ILE D CA  1 
ATOM   10453 C C   . ILE D 1 276 ? 35.100  -36.872 146.787 1.00 59.08  ? 295 ILE D C   1 
ATOM   10454 O O   . ILE D 1 276 ? 35.566  -36.225 147.729 1.00 61.34  ? 295 ILE D O   1 
ATOM   10455 C CB  . ILE D 1 276 ? 32.646  -37.251 147.189 1.00 63.78  ? 295 ILE D CB  1 
ATOM   10456 N N   . ASP D 1 277 ? 35.798  -37.829 146.159 1.00 60.14  ? 296 ASP D N   1 
ATOM   10457 C CA  . ASP D 1 277 ? 37.256  -37.874 146.283 1.00 58.85  ? 296 ASP D CA  1 
ATOM   10458 C C   . ASP D 1 277 ? 37.871  -36.596 145.709 1.00 57.35  ? 296 ASP D C   1 
ATOM   10459 O O   . ASP D 1 277 ? 38.737  -35.966 146.329 1.00 56.17  ? 296 ASP D O   1 
ATOM   10460 C CB  . ASP D 1 277 ? 37.849  -39.103 145.566 1.00 58.14  ? 296 ASP D CB  1 
ATOM   10461 C CG  . ASP D 1 277 ? 37.494  -40.457 146.255 1.00 59.70  ? 296 ASP D CG  1 
ATOM   10462 O OD1 . ASP D 1 277 ? 37.554  -40.557 147.523 1.00 59.93  ? 296 ASP D OD1 1 
ATOM   10463 O OD2 . ASP D 1 277 ? 37.156  -41.413 145.498 1.00 58.95  ? 296 ASP D OD2 1 
ATOM   10464 N N   . ASP D 1 278 ? 37.410  -36.180 144.526 1.00 60.23  ? 297 ASP D N   1 
ATOM   10465 C CA  . ASP D 1 278 ? 37.994  -35.004 143.895 1.00 58.27  ? 297 ASP D CA  1 
ATOM   10466 C C   . ASP D 1 278 ? 37.869  -33.760 144.787 1.00 58.42  ? 297 ASP D C   1 
ATOM   10467 O O   . ASP D 1 278 ? 38.722  -32.868 144.718 1.00 55.71  ? 297 ASP D O   1 
ATOM   10468 C CB  . ASP D 1 278 ? 37.359  -34.785 142.517 1.00 56.24  ? 297 ASP D CB  1 
ATOM   10469 C CG  . ASP D 1 278 ? 37.736  -35.910 141.481 1.00 56.06  ? 297 ASP D CG  1 
ATOM   10470 O OD1 . ASP D 1 278 ? 36.841  -36.304 140.635 1.00 54.36  ? 297 ASP D OD1 1 
ATOM   10471 O OD2 . ASP D 1 278 ? 38.888  -36.393 141.473 1.00 55.93  ? 297 ASP D OD2 1 
ATOM   10472 N N   . GLN D 1 279 ? 36.844  -33.687 145.653 1.00 56.61  ? 298 GLN D N   1 
ATOM   10473 C CA  . GLN D 1 279 ? 36.753  -32.562 146.582 1.00 58.09  ? 298 GLN D CA  1 
ATOM   10474 C C   . GLN D 1 279 ? 37.730  -32.715 147.746 1.00 58.38  ? 298 GLN D C   1 
ATOM   10475 O O   . GLN D 1 279 ? 38.136  -31.712 148.354 1.00 59.63  ? 298 GLN D O   1 
ATOM   10476 C CB  . GLN D 1 279 ? 35.322  -32.413 147.100 1.00 62.00  ? 298 GLN D CB  1 
ATOM   10477 N N   . ALA D 1 280 ? 38.125  -33.943 148.076 1.00 58.49  ? 299 ALA D N   1 
ATOM   10478 C CA  . ALA D 1 280 ? 39.169  -34.097 149.081 1.00 57.84  ? 299 ALA D CA  1 
ATOM   10479 C C   . ALA D 1 280 ? 40.525  -33.669 148.533 1.00 54.42  ? 299 ALA D C   1 
ATOM   10480 O O   . ALA D 1 280 ? 41.406  -33.240 149.292 1.00 55.17  ? 299 ALA D O   1 
ATOM   10481 C CB  . ALA D 1 280 ? 39.253  -35.547 149.569 1.00 58.04  ? 299 ALA D CB  1 
ATOM   10482 N N   . MET D 1 281 ? 40.715  -33.810 147.234 1.00 56.54  ? 300 MET D N   1 
ATOM   10483 C CA  . MET D 1 281 ? 41.945  -33.385 146.593 1.00 53.26  ? 300 MET D CA  1 
ATOM   10484 C C   . MET D 1 281 ? 41.974  -31.862 146.311 1.00 51.69  ? 300 MET D C   1 
ATOM   10485 O O   . MET D 1 281 ? 42.861  -31.391 145.597 1.00 49.70  ? 300 MET D O   1 
ATOM   10486 C CB  . MET D 1 281 ? 42.135  -34.159 145.290 1.00 51.95  ? 300 MET D CB  1 
ATOM   10487 C CG  . MET D 1 281 ? 42.623  -35.594 145.405 1.00 53.31  ? 300 MET D CG  1 
ATOM   10488 S SD  . MET D 1 281 ? 43.960  -35.981 146.485 1.00 49.70  ? 300 MET D SD  1 
ATOM   10489 C CE  . MET D 1 281 ? 45.406  -35.822 145.389 1.00 44.46  ? 300 MET D CE  1 
ATOM   10490 N N   . ARG D 1 282 ? 41.015  -31.092 146.811 1.00 48.74  ? 301 ARG D N   1 
ATOM   10491 C CA  . ARG D 1 282 ? 41.063  -29.644 146.695 1.00 50.19  ? 301 ARG D CA  1 
ATOM   10492 C C   . ARG D 1 282 ? 41.484  -29.001 148.006 1.00 53.39  ? 301 ARG D C   1 
ATOM   10493 O O   . ARG D 1 282 ? 41.257  -27.805 148.206 1.00 56.19  ? 301 ARG D O   1 
ATOM   10494 C CB  . ARG D 1 282 ? 39.710  -29.096 146.228 1.00 52.61  ? 301 ARG D CB  1 
ATOM   10495 C CG  . ARG D 1 282 ? 39.520  -29.126 144.701 1.00 50.23  ? 301 ARG D CG  1 
ATOM   10496 C CD  . ARG D 1 282 ? 38.095  -28.776 144.262 1.00 52.54  ? 301 ARG D CD  1 
ATOM   10497 N NE  . ARG D 1 282 ? 37.679  -27.420 144.660 1.00 56.73  ? 301 ARG D NE  1 
ATOM   10498 C CZ  . ARG D 1 282 ? 38.128  -26.295 144.108 1.00 57.34  ? 301 ARG D CZ  1 
ATOM   10499 N NH1 . ARG D 1 282 ? 39.013  -26.329 143.121 1.00 54.53  ? 301 ARG D NH1 1 
ATOM   10500 N NH2 . ARG D 1 282 ? 37.685  -25.112 144.559 1.00 61.64  ? 301 ARG D NH2 1 
ATOM   10501 N N   . LYS D 1 283 ? 42.045  -29.775 148.912 1.00 52.12  ? 302 LYS D N   1 
ATOM   10502 C CA  . LYS D 1 283 ? 42.450  -29.382 150.247 1.00 56.11  ? 302 LYS D CA  1 
ATOM   10503 C C   . LYS D 1 283 ? 43.971  -29.243 150.253 1.00 55.71  ? 302 LYS D C   1 
ATOM   10504 O O   . LYS D 1 283 ? 44.658  -29.625 149.301 1.00 53.28  ? 302 LYS D O   1 
ATOM   10505 C CB  . LYS D 1 283 ? 41.971  -30.445 151.266 1.00 56.81  ? 302 LYS D CB  1 
ATOM   10506 C CG  . LYS D 1 283 ? 40.688  -30.027 152.086 1.00 59.74  ? 302 LYS D CG  1 
ATOM   10507 C CD  . LYS D 1 283 ? 39.547  -29.651 151.155 1.00 66.16  ? 302 LYS D CD  1 
ATOM   10508 C CE  . LYS D 1 283 ? 38.163  -29.708 151.799 1.00 68.64  ? 302 LYS D CE  1 
ATOM   10509 N NZ  . LYS D 1 283 ? 37.154  -30.198 150.761 1.00 65.03  ? 302 LYS D NZ  1 
ATOM   10510 N N   . PRO D 1 284 ? 44.546  -28.686 151.323 1.00 59.39  ? 303 PRO D N   1 
ATOM   10511 C CA  . PRO D 1 284 ? 45.993  -28.427 151.315 1.00 60.16  ? 303 PRO D CA  1 
ATOM   10512 C C   . PRO D 1 284 ? 46.841  -29.604 150.845 1.00 56.94  ? 303 PRO D C   1 
ATOM   10513 O O   . PRO D 1 284 ? 46.479  -30.780 150.994 1.00 55.47  ? 303 PRO D O   1 
ATOM   10514 C CB  . PRO D 1 284 ? 46.310  -28.084 152.780 1.00 63.58  ? 303 PRO D CB  1 
ATOM   10515 C CG  . PRO D 1 284 ? 45.065  -27.593 153.307 1.00 66.76  ? 303 PRO D CG  1 
ATOM   10516 C CD  . PRO D 1 284 ? 43.971  -28.394 152.645 1.00 64.48  ? 303 PRO D CD  1 
ATOM   10517 N N   . LEU D 1 285 ? 48.004  -29.255 150.284 1.00 50.75  ? 304 LEU D N   1 
ATOM   10518 C CA  . LEU D 1 285 ? 48.910  -30.248 149.716 1.00 48.79  ? 304 LEU D CA  1 
ATOM   10519 C C   . LEU D 1 285 ? 49.255  -31.343 150.702 1.00 49.30  ? 304 LEU D C   1 
ATOM   10520 O O   . LEU D 1 285 ? 49.535  -32.474 150.300 1.00 47.47  ? 304 LEU D O   1 
ATOM   10521 C CB  . LEU D 1 285 ? 50.186  -29.546 149.260 1.00 49.44  ? 304 LEU D CB  1 
ATOM   10522 C CG  . LEU D 1 285 ? 51.267  -30.469 148.693 1.00 47.95  ? 304 LEU D CG  1 
ATOM   10523 C CD1 . LEU D 1 285 ? 50.673  -31.213 147.532 1.00 45.05  ? 304 LEU D CD1 1 
ATOM   10524 C CD2 . LEU D 1 285 ? 52.459  -29.599 148.305 1.00 49.13  ? 304 LEU D CD2 1 
ATOM   10525 N N   . THR D 1 286 ? 49.249  -31.030 151.987 1.00 52.07  ? 305 THR D N   1 
ATOM   10526 C CA  . THR D 1 286 ? 49.449  -32.055 152.987 1.00 52.81  ? 305 THR D CA  1 
ATOM   10527 C C   . THR D 1 286 ? 48.314  -33.070 152.934 1.00 51.46  ? 305 THR D C   1 
ATOM   10528 O O   . THR D 1 286 ? 48.569  -34.265 152.834 1.00 50.43  ? 305 THR D O   1 
ATOM   10529 C CB  . THR D 1 286 ? 49.608  -31.404 154.358 1.00 56.41  ? 305 THR D CB  1 
ATOM   10530 O OG1 . THR D 1 286 ? 50.867  -30.730 154.359 1.00 57.63  ? 305 THR D OG1 1 
ATOM   10531 C CG2 . THR D 1 286 ? 49.644  -32.427 155.468 1.00 57.65  ? 305 THR D CG2 1 
ATOM   10532 N N   . GLN D 1 287 ? 47.055  -32.617 152.949 1.00 51.44  ? 306 GLN D N   1 
ATOM   10533 C CA  . GLN D 1 287 ? 45.961  -33.573 152.830 1.00 50.30  ? 306 GLN D CA  1 
ATOM   10534 C C   . GLN D 1 287 ? 46.057  -34.287 151.497 1.00 45.90  ? 306 GLN D C   1 
ATOM   10535 O O   . GLN D 1 287 ? 45.930  -35.520 151.443 1.00 43.68  ? 306 GLN D O   1 
ATOM   10536 C CB  . GLN D 1 287 ? 44.614  -32.893 153.009 1.00 51.61  ? 306 GLN D CB  1 
ATOM   10537 N N   . LYS D 1 288 ? 46.375  -33.551 150.416 1.00 50.25  ? 307 LYS D N   1 
ATOM   10538 C CA  . LYS D 1 288 ? 46.466  -34.173 149.092 1.00 48.33  ? 307 LYS D CA  1 
ATOM   10539 C C   . LYS D 1 288 ? 47.437  -35.361 149.080 1.00 47.77  ? 307 LYS D C   1 
ATOM   10540 O O   . LYS D 1 288 ? 47.140  -36.416 148.509 1.00 46.34  ? 307 LYS D O   1 
ATOM   10541 C CB  . LYS D 1 288 ? 46.925  -33.170 148.037 1.00 46.78  ? 307 LYS D CB  1 
ATOM   10542 C CG  . LYS D 1 288 ? 45.899  -32.155 147.516 1.00 46.67  ? 307 LYS D CG  1 
ATOM   10543 C CD  . LYS D 1 288 ? 46.518  -31.445 146.278 1.00 46.57  ? 307 LYS D CD  1 
ATOM   10544 C CE  . LYS D 1 288 ? 45.614  -30.419 145.624 1.00 46.56  ? 307 LYS D CE  1 
ATOM   10545 N NZ  . LYS D 1 288 ? 45.159  -29.385 146.607 1.00 47.48  ? 307 LYS D NZ  1 
ATOM   10546 N N   . ARG D 1 289 ? 48.626  -35.187 149.680 1.00 46.55  ? 308 ARG D N   1 
ATOM   10547 C CA  . ARG D 1 289 ? 49.627  -36.250 149.651 1.00 45.93  ? 308 ARG D CA  1 
ATOM   10548 C C   . ARG D 1 289 ? 49.146  -37.493 150.397 1.00 46.48  ? 308 ARG D C   1 
ATOM   10549 O O   . ARG D 1 289 ? 49.356  -38.613 149.935 1.00 45.16  ? 308 ARG D O   1 
ATOM   10550 C CB  . ARG D 1 289 ? 50.954  -35.749 150.242 1.00 46.53  ? 308 ARG D CB  1 
ATOM   10551 C CG  . ARG D 1 289 ? 51.740  -34.941 149.271 1.00 47.32  ? 308 ARG D CG  1 
ATOM   10552 C CD  . ARG D 1 289 ? 53.056  -34.389 149.804 1.00 48.79  ? 308 ARG D CD  1 
ATOM   10553 N NE  . ARG D 1 289 ? 53.708  -33.676 148.700 1.00 49.67  ? 308 ARG D NE  1 
ATOM   10554 C CZ  . ARG D 1 289 ? 54.543  -32.662 148.821 1.00 49.38  ? 308 ARG D CZ  1 
ATOM   10555 N NH1 . ARG D 1 289 ? 54.900  -32.211 150.003 1.00 52.48  ? 308 ARG D NH1 1 
ATOM   10556 N NH2 . ARG D 1 289 ? 55.037  -32.097 147.723 1.00 50.49  ? 308 ARG D NH2 1 
ATOM   10557 N N   . ARG D 1 290 ? 48.538  -37.311 151.581 1.00 45.33  ? 309 ARG D N   1 
ATOM   10558 C CA  . ARG D 1 290 ? 48.064  -38.456 152.352 1.00 45.88  ? 309 ARG D CA  1 
ATOM   10559 C C   . ARG D 1 290 ? 47.059  -39.238 151.532 1.00 44.11  ? 309 ARG D C   1 
ATOM   10560 O O   . ARG D 1 290 ? 47.125  -40.475 151.485 1.00 44.48  ? 309 ARG D O   1 
ATOM   10561 C CB  . ARG D 1 290 ? 47.475  -38.014 153.702 1.00 48.77  ? 309 ARG D CB  1 
ATOM   10562 N N   . VAL D 1 291 ? 46.182  -38.539 150.795 1.00 43.39  ? 310 VAL D N   1 
ATOM   10563 C CA  . VAL D 1 291 ? 45.202  -39.248 149.976 1.00 43.44  ? 310 VAL D CA  1 
ATOM   10564 C C   . VAL D 1 291 ? 45.901  -39.960 148.828 1.00 42.47  ? 310 VAL D C   1 
ATOM   10565 O O   . VAL D 1 291 ? 45.606  -41.128 148.532 1.00 42.83  ? 310 VAL D O   1 
ATOM   10566 C CB  . VAL D 1 291 ? 44.102  -38.305 149.452 1.00 43.45  ? 310 VAL D CB  1 
ATOM   10567 C CG1 . VAL D 1 291 ? 43.194  -39.037 148.443 1.00 43.44  ? 310 VAL D CG1 1 
ATOM   10568 C CG2 . VAL D 1 291 ? 43.280  -37.736 150.607 1.00 44.67  ? 310 VAL D CG2 1 
ATOM   10569 N N   . ALA D 1 292 ? 46.863  -39.287 148.191 1.00 42.25  ? 311 ALA D N   1 
ATOM   10570 C CA  . ALA D 1 292 ? 47.579  -39.905 147.079 1.00 41.32  ? 311 ALA D CA  1 
ATOM   10571 C C   . ALA D 1 292 ? 48.373  -41.131 147.540 1.00 41.75  ? 311 ALA D C   1 
ATOM   10572 O O   . ALA D 1 292 ? 48.365  -42.167 146.860 1.00 41.66  ? 311 ALA D O   1 
ATOM   10573 C CB  . ALA D 1 292 ? 48.519  -38.913 146.403 1.00 40.14  ? 311 ALA D CB  1 
ATOM   10574 N N   . LYS D 1 293 ? 49.109  -40.999 148.673 1.00 41.70  ? 312 LYS D N   1 
ATOM   10575 C CA  . LYS D 1 293 ? 49.788  -42.127 149.306 1.00 42.41  ? 312 LYS D CA  1 
ATOM   10576 C C   . LYS D 1 293 ? 48.798  -43.261 149.508 1.00 43.15  ? 312 LYS D C   1 
ATOM   10577 O O   . LYS D 1 293 ? 48.943  -44.319 148.920 1.00 43.02  ? 312 LYS D O   1 
ATOM   10578 C CB  . LYS D 1 293 ? 50.426  -41.717 150.634 1.00 43.23  ? 312 LYS D CB  1 
ATOM   10579 N N   . ASP D 1 294 ? 47.736  -43.042 150.278 1.00 42.52  ? 313 ASP D N   1 
ATOM   10580 C CA  . ASP D 1 294 ? 46.796  -44.134 150.539 1.00 43.96  ? 313 ASP D CA  1 
ATOM   10581 C C   . ASP D 1 294 ? 46.065  -44.607 149.282 1.00 43.48  ? 313 ASP D C   1 
ATOM   10582 O O   . ASP D 1 294 ? 45.640  -45.763 149.229 1.00 44.51  ? 313 ASP D O   1 
ATOM   10583 C CB  . ASP D 1 294 ? 45.789  -43.716 151.627 1.00 46.10  ? 313 ASP D CB  1 
ATOM   10584 N N   . SER D 1 295 ? 45.975  -43.800 148.232 1.00 43.31  ? 314 SER D N   1 
ATOM   10585 C CA  . SER D 1 295 ? 45.203  -44.143 147.037 1.00 43.12  ? 314 SER D CA  1 
ATOM   10586 C C   . SER D 1 295 ? 46.010  -44.852 145.936 1.00 42.16  ? 314 SER D C   1 
ATOM   10587 O O   . SER D 1 295 ? 45.442  -45.207 144.893 1.00 41.89  ? 314 SER D O   1 
ATOM   10588 C CB  . SER D 1 295 ? 44.582  -42.857 146.455 1.00 42.83  ? 314 SER D CB  1 
ATOM   10589 O OG  . SER D 1 295 ? 43.616  -42.313 147.332 1.00 43.86  ? 314 SER D OG  1 
ATOM   10590 N N   . LEU D 1 296 ? 47.302  -45.074 146.117 1.00 41.76  ? 315 LEU D N   1 
ATOM   10591 C CA  . LEU D 1 296 ? 48.113  -45.554 145.003 1.00 39.90  ? 315 LEU D CA  1 
ATOM   10592 C C   . LEU D 1 296 ? 47.919  -47.055 144.711 1.00 39.83  ? 315 LEU D C   1 
ATOM   10593 O O   . LEU D 1 296 ? 47.827  -47.447 143.538 1.00 38.55  ? 315 LEU D O   1 
ATOM   10594 C CB  . LEU D 1 296 ? 49.583  -45.238 145.292 1.00 39.61  ? 315 LEU D CB  1 
ATOM   10595 C CG  . LEU D 1 296 ? 50.613  -45.899 144.395 1.00 38.05  ? 315 LEU D CG  1 
ATOM   10596 C CD1 . LEU D 1 296 ? 50.526  -45.300 143.003 1.00 36.66  ? 315 LEU D CD1 1 
ATOM   10597 C CD2 . LEU D 1 296 ? 52.013  -45.760 144.964 1.00 38.51  ? 315 LEU D CD2 1 
ATOM   10598 N N   . LYS D 1 297 ? 47.830  -47.899 145.744 1.00 37.61  ? 316 LYS D N   1 
ATOM   10599 C CA  . LYS D 1 297 ? 47.905  -49.356 145.555 1.00 37.12  ? 316 LYS D CA  1 
ATOM   10600 C C   . LYS D 1 297 ? 46.905  -49.841 144.507 1.00 36.91  ? 316 LYS D C   1 
ATOM   10601 O O   . LYS D 1 297 ? 47.257  -50.614 143.616 1.00 35.85  ? 316 LYS D O   1 
ATOM   10602 C CB  . LYS D 1 297 ? 47.683  -50.102 146.869 1.00 38.80  ? 316 LYS D CB  1 
ATOM   10603 N N   . PHE D 1 298 ? 45.656  -49.366 144.581 1.00 39.35  ? 317 PHE D N   1 
ATOM   10604 C CA  . PHE D 1 298 ? 44.626  -49.942 143.724 1.00 39.30  ? 317 PHE D CA  1 
ATOM   10605 C C   . PHE D 1 298 ? 44.927  -49.732 142.247 1.00 37.39  ? 317 PHE D C   1 
ATOM   10606 O O   . PHE D 1 298 ? 45.035  -50.722 141.501 1.00 36.71  ? 317 PHE D O   1 
ATOM   10607 C CB  . PHE D 1 298 ? 43.246  -49.381 144.042 1.00 41.03  ? 317 PHE D CB  1 
ATOM   10608 C CG  . PHE D 1 298 ? 42.188  -49.914 143.116 1.00 41.38  ? 317 PHE D CG  1 
ATOM   10609 C CD1 . PHE D 1 298 ? 41.731  -51.196 143.247 1.00 41.51  ? 317 PHE D CD1 1 
ATOM   10610 C CD2 . PHE D 1 298 ? 41.709  -49.153 142.065 1.00 41.49  ? 317 PHE D CD2 1 
ATOM   10611 C CE1 . PHE D 1 298 ? 40.789  -51.683 142.375 1.00 41.85  ? 317 PHE D CE1 1 
ATOM   10612 C CE2 . PHE D 1 298 ? 40.769  -49.644 141.198 1.00 41.82  ? 317 PHE D CE2 1 
ATOM   10613 C CZ  . PHE D 1 298 ? 40.309  -50.892 141.350 1.00 41.86  ? 317 PHE D CZ  1 
ATOM   10614 N N   . PRO D 1 299 ? 45.036  -48.501 141.750 1.00 38.72  ? 318 PRO D N   1 
ATOM   10615 C CA  . PRO D 1 299 ? 45.372  -48.319 140.331 1.00 37.06  ? 318 PRO D CA  1 
ATOM   10616 C C   . PRO D 1 299 ? 46.717  -48.887 139.967 1.00 35.59  ? 318 PRO D C   1 
ATOM   10617 O O   . PRO D 1 299 ? 46.891  -49.332 138.832 1.00 34.40  ? 318 PRO D O   1 
ATOM   10618 C CB  . PRO D 1 299 ? 45.366  -46.793 140.158 1.00 36.91  ? 318 PRO D CB  1 
ATOM   10619 C CG  . PRO D 1 299 ? 45.604  -46.250 141.545 1.00 38.17  ? 318 PRO D CG  1 
ATOM   10620 C CD  . PRO D 1 299 ? 44.930  -47.220 142.475 1.00 39.66  ? 318 PRO D CD  1 
ATOM   10621 N N   . LEU D 1 300 ? 47.703  -48.843 140.867 1.00 37.25  ? 319 LEU D N   1 
ATOM   10622 C CA  . LEU D 1 300 ? 48.974  -49.468 140.538 1.00 36.41  ? 319 LEU D CA  1 
ATOM   10623 C C   . LEU D 1 300 ? 48.832  -50.986 140.400 1.00 36.48  ? 319 LEU D C   1 
ATOM   10624 O O   . LEU D 1 300 ? 49.586  -51.618 139.641 1.00 36.34  ? 319 LEU D O   1 
ATOM   10625 C CB  . LEU D 1 300 ? 50.014  -49.144 141.605 1.00 36.89  ? 319 LEU D CB  1 
ATOM   10626 C CG  . LEU D 1 300 ? 51.366  -49.852 141.426 1.00 36.47  ? 319 LEU D CG  1 
ATOM   10627 C CD1 . LEU D 1 300 ? 51.902  -49.408 140.049 1.00 35.65  ? 319 LEU D CD1 1 
ATOM   10628 C CD2 . LEU D 1 300 ? 52.353  -49.559 142.551 1.00 37.24  ? 319 LEU D CD2 1 
ATOM   10629 N N   . ALA D 1 301 ? 47.902  -51.588 141.141 1.00 35.18  ? 320 ALA D N   1 
ATOM   10630 C CA  . ALA D 1 301 ? 47.726  -53.033 141.046 1.00 35.68  ? 320 ALA D CA  1 
ATOM   10631 C C   . ALA D 1 301 ? 46.931  -53.385 139.794 1.00 35.13  ? 320 ALA D C   1 
ATOM   10632 O O   . ALA D 1 301 ? 47.273  -54.330 139.081 1.00 35.18  ? 320 ALA D O   1 
ATOM   10633 C CB  . ALA D 1 301 ? 47.033  -53.560 142.300 1.00 37.52  ? 320 ALA D CB  1 
ATOM   10634 N N   . CYS D 1 302 ? 45.904  -52.581 139.497 1.00 35.13  ? 321 CYS D N   1 
ATOM   10635 C CA  . CYS D 1 302 ? 45.185  -52.739 138.247 1.00 34.90  ? 321 CYS D CA  1 
ATOM   10636 C C   . CYS D 1 302 ? 46.164  -52.694 137.106 1.00 33.74  ? 321 CYS D C   1 
ATOM   10637 O O   . CYS D 1 302 ? 46.167  -53.550 136.227 1.00 34.03  ? 321 CYS D O   1 
ATOM   10638 C CB  . CYS D 1 302 ? 44.140  -51.659 138.104 1.00 35.58  ? 321 CYS D CB  1 
ATOM   10639 S SG  . CYS D 1 302 ? 42.797  -51.913 139.217 1.00 37.64  ? 321 CYS D SG  1 
ATOM   10640 N N   . PHE D 1 303 ? 47.032  -51.701 137.113 1.00 33.91  ? 322 PHE D N   1 
ATOM   10641 C CA  . PHE D 1 303 ? 48.031  -51.618 136.056 1.00 33.39  ? 322 PHE D CA  1 
ATOM   10642 C C   . PHE D 1 303 ? 48.848  -52.912 136.016 1.00 33.94  ? 322 PHE D C   1 
ATOM   10643 O O   . PHE D 1 303 ? 48.923  -53.586 134.983 1.00 34.44  ? 322 PHE D O   1 
ATOM   10644 C CB  . PHE D 1 303 ? 48.916  -50.376 136.280 1.00 32.86  ? 322 PHE D CB  1 
ATOM   10645 C CG  . PHE D 1 303 ? 50.063  -50.278 135.354 1.00 32.60  ? 322 PHE D CG  1 
ATOM   10646 C CD1 . PHE D 1 303 ? 49.898  -49.845 134.077 1.00 33.02  ? 322 PHE D CD1 1 
ATOM   10647 C CD2 . PHE D 1 303 ? 51.309  -50.614 135.763 1.00 33.26  ? 322 PHE D CD2 1 
ATOM   10648 C CE1 . PHE D 1 303 ? 50.965  -49.740 133.218 1.00 33.93  ? 322 PHE D CE1 1 
ATOM   10649 C CE2 . PHE D 1 303 ? 52.382  -50.535 134.905 1.00 33.76  ? 322 PHE D CE2 1 
ATOM   10650 C CZ  . PHE D 1 303 ? 52.207  -50.093 133.622 1.00 34.38  ? 322 PHE D CZ  1 
ATOM   10651 N N   . LEU D 1 304 ? 49.493  -53.254 137.139 1.00 34.92  ? 323 LEU D N   1 
ATOM   10652 C CA  . LEU D 1 304 ? 50.377  -54.398 137.138 1.00 35.39  ? 323 LEU D CA  1 
ATOM   10653 C C   . LEU D 1 304 ? 49.609  -55.670 136.823 1.00 36.27  ? 323 LEU D C   1 
ATOM   10654 O O   . LEU D 1 304 ? 50.144  -56.586 136.196 1.00 37.06  ? 323 LEU D O   1 
ATOM   10655 C CB  . LEU D 1 304 ? 51.060  -54.479 138.488 1.00 35.74  ? 323 LEU D CB  1 
ATOM   10656 C CG  . LEU D 1 304 ? 52.154  -53.434 138.691 1.00 35.50  ? 323 LEU D CG  1 
ATOM   10657 C CD1 . LEU D 1 304 ? 52.681  -53.546 140.079 1.00 36.07  ? 323 LEU D CD1 1 
ATOM   10658 C CD2 . LEU D 1 304 ? 53.255  -53.636 137.678 1.00 35.97  ? 323 LEU D CD2 1 
ATOM   10659 N N   . ALA D 1 305 ? 48.344  -55.721 137.217 1.00 35.18  ? 324 ALA D N   1 
ATOM   10660 C CA  . ALA D 1 305 ? 47.512  -56.855 136.883 1.00 36.05  ? 324 ALA D CA  1 
ATOM   10661 C C   . ALA D 1 305 ? 47.527  -57.131 135.386 1.00 36.15  ? 324 ALA D C   1 
ATOM   10662 O O   . ALA D 1 305 ? 47.631  -58.294 134.962 1.00 37.25  ? 324 ALA D O   1 
ATOM   10663 C CB  . ALA D 1 305 ? 46.097  -56.599 137.391 1.00 36.70  ? 324 ALA D CB  1 
ATOM   10664 N N   . GLY D 1 306 ? 47.445  -56.073 134.571 1.00 34.90  ? 325 GLY D N   1 
ATOM   10665 C CA  . GLY D 1 306 ? 47.266  -56.159 133.131 1.00 35.63  ? 325 GLY D CA  1 
ATOM   10666 C C   . GLY D 1 306 ? 48.497  -55.856 132.302 1.00 36.16  ? 325 GLY D C   1 
ATOM   10667 O O   . GLY D 1 306 ? 48.513  -56.111 131.110 1.00 37.35  ? 325 GLY D O   1 
ATOM   10668 N N   . ALA D 1 307 ? 49.555  -55.348 132.907 1.00 37.10  ? 326 ALA D N   1 
ATOM   10669 C CA  . ALA D 1 307 ? 50.612  -54.732 132.124 1.00 37.83  ? 326 ALA D CA  1 
ATOM   10670 C C   . ALA D 1 307 ? 51.343  -55.749 131.258 1.00 39.60  ? 326 ALA D C   1 
ATOM   10671 O O   . ALA D 1 307 ? 51.562  -56.890 131.647 1.00 40.19  ? 326 ALA D O   1 
ATOM   10672 C CB  . ALA D 1 307 ? 51.619  -53.999 133.040 1.00 37.27  ? 326 ALA D CB  1 
ATOM   10673 N N   . GLN D 1 308 ? 51.758  -55.300 130.080 1.00 38.53  ? 327 GLN D N   1 
ATOM   10674 C CA  . GLN D 1 308 ? 52.633  -56.048 129.201 1.00 40.43  ? 327 GLN D CA  1 
ATOM   10675 C C   . GLN D 1 308 ? 53.802  -55.167 128.800 1.00 41.05  ? 327 GLN D C   1 
ATOM   10676 O O   . GLN D 1 308 ? 53.931  -54.038 129.253 1.00 39.86  ? 327 GLN D O   1 
ATOM   10677 C CB  . GLN D 1 308 ? 51.884  -56.521 127.963 1.00 42.40  ? 327 GLN D CB  1 
ATOM   10678 C CG  . GLN D 1 308 ? 50.517  -57.054 128.271 1.00 41.86  ? 327 GLN D CG  1 
ATOM   10679 C CD  . GLN D 1 308 ? 50.547  -58.358 129.011 1.00 41.74  ? 327 GLN D CD  1 
ATOM   10680 O OE1 . GLN D 1 308 ? 51.320  -59.262 128.687 1.00 43.78  ? 327 GLN D OE1 1 
ATOM   10681 N NE2 . GLN D 1 308 ? 49.698  -58.466 130.010 1.00 40.50  ? 327 GLN D NE2 1 
ATOM   10682 N N   . GLU D 1 309 ? 54.678  -55.693 127.946 1.00 44.56  ? 328 GLU D N   1 
ATOM   10683 C CA  . GLU D 1 309 ? 55.749  -54.862 127.413 1.00 45.55  ? 328 GLU D CA  1 
ATOM   10684 C C   . GLU D 1 309 ? 55.128  -53.578 126.851 1.00 44.93  ? 328 GLU D C   1 
ATOM   10685 O O   . GLU D 1 309 ? 54.036  -53.588 126.265 1.00 45.50  ? 328 GLU D O   1 
ATOM   10686 C CB  . GLU D 1 309 ? 56.557  -55.590 126.326 1.00 48.98  ? 328 GLU D CB  1 
ATOM   10687 C CG  . GLU D 1 309 ? 56.844  -57.064 126.570 1.00 51.79  ? 328 GLU D CG  1 
ATOM   10688 C CD  . GLU D 1 309 ? 57.974  -57.310 127.545 1.00 53.18  ? 328 GLU D CD  1 
ATOM   10689 O OE1 . GLU D 1 309 ? 58.847  -56.415 127.612 1.00 53.66  ? 328 GLU D OE1 1 
ATOM   10690 O OE2 . GLU D 1 309 ? 58.002  -58.391 128.228 1.00 53.23  ? 328 GLU D OE2 1 
ATOM   10691 N N   . ASN D 1 310 ? 55.811  -52.461 127.056 1.00 43.55  ? 329 ASN D N   1 
ATOM   10692 C CA  . ASN D 1 310 ? 55.397  -51.182 126.499 1.00 43.24  ? 329 ASN D CA  1 
ATOM   10693 C C   . ASN D 1 310 ? 54.114  -50.633 127.115 1.00 41.52  ? 329 ASN D C   1 
ATOM   10694 O O   . ASN D 1 310 ? 53.456  -49.798 126.493 1.00 41.75  ? 329 ASN D O   1 
ATOM   10695 C CB  . ASN D 1 310 ? 55.196  -51.281 124.981 1.00 45.31  ? 329 ASN D CB  1 
ATOM   10696 C CG  . ASN D 1 310 ? 56.414  -51.782 124.257 1.00 47.26  ? 329 ASN D CG  1 
ATOM   10697 O OD1 . ASN D 1 310 ? 57.503  -51.259 124.449 1.00 47.55  ? 329 ASN D OD1 1 
ATOM   10698 N ND2 . ASN D 1 310 ? 56.230  -52.768 123.376 1.00 49.38  ? 329 ASN D ND2 1 
ATOM   10699 N N   . CYS D 1 311 ? 53.722  -51.086 128.303 1.00 41.80  ? 330 CYS D N   1 
ATOM   10700 C CA  . CYS D 1 311 ? 52.705  -50.401 129.084 1.00 39.98  ? 330 CYS D CA  1 
ATOM   10701 C C   . CYS D 1 311 ? 53.364  -49.517 130.137 1.00 38.81  ? 330 CYS D C   1 
ATOM   10702 O O   . CYS D 1 311 ? 54.329  -49.939 130.798 1.00 39.08  ? 330 CYS D O   1 
ATOM   10703 C CB  . CYS D 1 311 ? 51.780  -51.395 129.766 1.00 39.45  ? 330 CYS D CB  1 
ATOM   10704 S SG  . CYS D 1 311 ? 50.787  -52.327 128.650 1.00 41.15  ? 330 CYS D SG  1 
ATOM   10705 N N   . TYR D 1 312 ? 52.830  -48.291 130.301 1.00 39.58  ? 331 TYR D N   1 
ATOM   10706 C CA  . TYR D 1 312 ? 53.381  -47.313 131.239 1.00 38.62  ? 331 TYR D CA  1 
ATOM   10707 C C   . TYR D 1 312 ? 52.287  -46.761 132.140 1.00 37.10  ? 331 TYR D C   1 
ATOM   10708 O O   . TYR D 1 312 ? 51.133  -46.607 131.726 1.00 37.04  ? 331 TYR D O   1 
ATOM   10709 C CB  . TYR D 1 312 ? 54.074  -46.133 130.526 1.00 39.55  ? 331 TYR D CB  1 
ATOM   10710 C CG  . TYR D 1 312 ? 55.188  -46.544 129.611 1.00 41.18  ? 331 TYR D CG  1 
ATOM   10711 C CD1 . TYR D 1 312 ? 54.907  -47.108 128.365 1.00 42.59  ? 331 TYR D CD1 1 
ATOM   10712 C CD2 . TYR D 1 312 ? 56.514  -46.402 129.984 1.00 41.80  ? 331 TYR D CD2 1 
ATOM   10713 C CE1 . TYR D 1 312 ? 55.916  -47.521 127.514 1.00 44.08  ? 331 TYR D CE1 1 
ATOM   10714 C CE2 . TYR D 1 312 ? 57.545  -46.793 129.126 1.00 43.57  ? 331 TYR D CE2 1 
ATOM   10715 C CZ  . TYR D 1 312 ? 57.231  -47.361 127.878 1.00 44.91  ? 331 TYR D CZ  1 
ATOM   10716 O OH  . TYR D 1 312 ? 58.188  -47.782 126.959 1.00 47.00  ? 331 TYR D OH  1 
ATOM   10717 N N   . PHE D 1 313 ? 52.671  -46.439 133.374 1.00 36.15  ? 332 PHE D N   1 
ATOM   10718 C CA  . PHE D 1 313 ? 51.780  -45.926 134.411 1.00 35.15  ? 332 PHE D CA  1 
ATOM   10719 C C   . PHE D 1 313 ? 52.057  -44.453 134.705 1.00 34.95  ? 332 PHE D C   1 
ATOM   10720 O O   . PHE D 1 313 ? 53.207  -43.988 134.658 1.00 35.46  ? 332 PHE D O   1 
ATOM   10721 C CB  . PHE D 1 313 ? 51.974  -46.765 135.672 1.00 35.23  ? 332 PHE D CB  1 
ATOM   10722 C CG  . PHE D 1 313 ? 50.969  -46.535 136.766 1.00 34.72  ? 332 PHE D CG  1 
ATOM   10723 C CD1 . PHE D 1 313 ? 49.624  -46.746 136.564 1.00 34.80  ? 332 PHE D CD1 1 
ATOM   10724 C CD2 . PHE D 1 313 ? 51.394  -46.211 138.043 1.00 34.95  ? 332 PHE D CD2 1 
ATOM   10725 C CE1 . PHE D 1 313 ? 48.708  -46.578 137.618 1.00 35.46  ? 332 PHE D CE1 1 
ATOM   10726 C CE2 . PHE D 1 313 ? 50.483  -46.048 139.086 1.00 35.55  ? 332 PHE D CE2 1 
ATOM   10727 C CZ  . PHE D 1 313 ? 49.156  -46.224 138.881 1.00 36.00  ? 332 PHE D CZ  1 
ATOM   10728 N N   . ILE D 1 314 ? 50.981  -43.724 134.993 1.00 37.58  ? 333 ILE D N   1 
ATOM   10729 C CA  . ILE D 1 314 ? 51.041  -42.327 135.425 1.00 37.43  ? 333 ILE D CA  1 
ATOM   10730 C C   . ILE D 1 314 ? 50.105  -42.187 136.622 1.00 37.19  ? 333 ILE D C   1 
ATOM   10731 O O   . ILE D 1 314 ? 48.953  -42.630 136.585 1.00 37.73  ? 333 ILE D O   1 
ATOM   10732 C CB  . ILE D 1 314 ? 50.626  -41.322 134.326 1.00 37.40  ? 333 ILE D CB  1 
ATOM   10733 C CG1 . ILE D 1 314 ? 51.475  -41.498 133.069 1.00 38.75  ? 333 ILE D CG1 1 
ATOM   10734 C CG2 . ILE D 1 314 ? 50.737  -39.916 134.879 1.00 37.74  ? 333 ILE D CG2 1 
ATOM   10735 C CD1 . ILE D 1 314 ? 51.207  -40.452 131.937 1.00 39.44  ? 333 ILE D CD1 1 
ATOM   10736 N N   . TYR D 1 315 ? 50.588  -41.579 137.683 1.00 35.97  ? 334 TYR D N   1 
ATOM   10737 C CA  . TYR D 1 315 ? 49.792  -41.447 138.892 1.00 36.62  ? 334 TYR D CA  1 
ATOM   10738 C C   . TYR D 1 315 ? 50.041  -40.045 139.391 1.00 36.93  ? 334 TYR D C   1 
ATOM   10739 O O   . TYR D 1 315 ? 51.188  -39.710 139.707 1.00 37.66  ? 334 TYR D O   1 
ATOM   10740 C CB  . TYR D 1 315 ? 50.172  -42.489 139.950 1.00 37.41  ? 334 TYR D CB  1 
ATOM   10741 C CG  . TYR D 1 315 ? 49.296  -42.401 141.196 1.00 38.69  ? 334 TYR D CG  1 
ATOM   10742 C CD1 . TYR D 1 315 ? 47.974  -42.862 141.184 1.00 39.21  ? 334 TYR D CD1 1 
ATOM   10743 C CD2 . TYR D 1 315 ? 49.788  -41.854 142.377 1.00 39.81  ? 334 TYR D CD2 1 
ATOM   10744 C CE1 . TYR D 1 315 ? 47.180  -42.771 142.319 1.00 41.03  ? 334 TYR D CE1 1 
ATOM   10745 C CE2 . TYR D 1 315 ? 49.008  -41.775 143.506 1.00 41.43  ? 334 TYR D CE2 1 
ATOM   10746 C CZ  . TYR D 1 315 ? 47.705  -42.218 143.476 1.00 42.15  ? 334 TYR D CZ  1 
ATOM   10747 O OH  . TYR D 1 315 ? 46.928  -42.140 144.618 1.00 44.24  ? 334 TYR D OH  1 
ATOM   10748 N N   . ASN D 1 316 ? 48.989  -39.241 139.394 1.00 40.96  ? 335 ASN D N   1 
ATOM   10749 C CA  . ASN D 1 316 ? 48.992  -37.884 139.914 1.00 41.12  ? 335 ASN D CA  1 
ATOM   10750 C C   . ASN D 1 316 ? 47.543  -37.414 139.940 1.00 41.49  ? 335 ASN D C   1 
ATOM   10751 O O   . ASN D 1 316 ? 46.604  -38.204 139.749 1.00 41.59  ? 335 ASN D O   1 
ATOM   10752 C CB  . ASN D 1 316 ? 49.856  -36.968 139.064 1.00 41.71  ? 335 ASN D CB  1 
ATOM   10753 C CG  . ASN D 1 316 ? 49.521  -37.066 137.583 1.00 41.05  ? 335 ASN D CG  1 
ATOM   10754 O OD1 . ASN D 1 316 ? 48.354  -36.919 137.148 1.00 40.38  ? 335 ASN D OD1 1 
ATOM   10755 N ND2 . ASN D 1 316 ? 50.560  -37.306 136.786 1.00 41.55  ? 335 ASN D ND2 1 
ATOM   10756 N N   . TRP D 1 317 ? 47.353  -36.123 140.135 1.00 41.40  ? 336 TRP D N   1 
ATOM   10757 C CA  . TRP D 1 317 ? 46.000  -35.601 140.147 1.00 40.71  ? 336 TRP D CA  1 
ATOM   10758 C C   . TRP D 1 317 ? 45.828  -34.425 139.194 1.00 41.09  ? 336 TRP D C   1 
ATOM   10759 O O   . TRP D 1 317 ? 44.988  -33.569 139.427 1.00 41.45  ? 336 TRP D O   1 
ATOM   10760 C CB  . TRP D 1 317 ? 45.604  -35.215 141.566 1.00 41.45  ? 336 TRP D CB  1 
ATOM   10761 C CG  . TRP D 1 317 ? 46.562  -34.256 142.223 1.00 42.89  ? 336 TRP D CG  1 
ATOM   10762 C CD1 . TRP D 1 317 ? 46.560  -32.892 142.104 1.00 43.94  ? 336 TRP D CD1 1 
ATOM   10763 C CD2 . TRP D 1 317 ? 47.661  -34.583 143.093 1.00 43.66  ? 336 TRP D CD2 1 
ATOM   10764 N NE1 . TRP D 1 317 ? 47.569  -32.361 142.860 1.00 45.29  ? 336 TRP D NE1 1 
ATOM   10765 C CE2 . TRP D 1 317 ? 48.263  -33.371 143.473 1.00 45.16  ? 336 TRP D CE2 1 
ATOM   10766 C CE3 . TRP D 1 317 ? 48.182  -35.772 143.586 1.00 43.37  ? 336 TRP D CE3 1 
ATOM   10767 C CZ2 . TRP D 1 317 ? 49.360  -33.315 144.328 1.00 46.38  ? 336 TRP D CZ2 1 
ATOM   10768 C CZ3 . TRP D 1 317 ? 49.271  -35.715 144.418 1.00 44.59  ? 336 TRP D CZ3 1 
ATOM   10769 C CH2 . TRP D 1 317 ? 49.847  -34.499 144.792 1.00 46.08  ? 336 TRP D CH2 1 
ATOM   10770 N N   . GLY D 1 318 ? 46.599  -34.370 138.113 1.00 41.21  ? 337 GLY D N   1 
ATOM   10771 C CA  . GLY D 1 318 ? 46.295  -33.428 137.060 1.00 41.69  ? 337 GLY D CA  1 
ATOM   10772 C C   . GLY D 1 318 ? 47.405  -33.326 136.033 1.00 42.31  ? 337 GLY D C   1 
ATOM   10773 O O   . GLY D 1 318 ? 48.395  -34.058 136.070 1.00 43.09  ? 337 GLY D O   1 
ATOM   10774 N N   . TYR D 1 319 ? 47.237  -32.324 135.151 1.00 45.20  ? 338 TYR D N   1 
ATOM   10775 C CA  . TYR D 1 319 ? 48.118  -32.108 134.012 1.00 46.33  ? 338 TYR D CA  1 
ATOM   10776 C C   . TYR D 1 319 ? 49.033  -30.900 134.147 1.00 48.30  ? 338 TYR D C   1 
ATOM   10777 O O   . TYR D 1 319 ? 49.900  -30.699 133.280 1.00 49.71  ? 338 TYR D O   1 
ATOM   10778 C CB  . TYR D 1 319 ? 47.257  -32.019 132.747 1.00 45.41  ? 338 TYR D CB  1 
ATOM   10779 C CG  . TYR D 1 319 ? 46.564  -33.333 132.536 1.00 43.98  ? 338 TYR D CG  1 
ATOM   10780 C CD1 . TYR D 1 319 ? 47.309  -34.474 132.299 1.00 44.62  ? 338 TYR D CD1 1 
ATOM   10781 C CD2 . TYR D 1 319 ? 45.179  -33.466 132.643 1.00 42.70  ? 338 TYR D CD2 1 
ATOM   10782 C CE1 . TYR D 1 319 ? 46.726  -35.694 132.133 1.00 43.47  ? 338 TYR D CE1 1 
ATOM   10783 C CE2 . TYR D 1 319 ? 44.580  -34.702 132.487 1.00 41.37  ? 338 TYR D CE2 1 
ATOM   10784 C CZ  . TYR D 1 319 ? 45.377  -35.817 132.230 1.00 41.79  ? 338 TYR D CZ  1 
ATOM   10785 O OH  . TYR D 1 319 ? 44.859  -37.106 132.060 1.00 41.00  ? 338 TYR D OH  1 
ATOM   10786 N N   . ARG D 1 320 ? 48.909  -30.126 135.220 1.00 48.38  ? 339 ARG D N   1 
ATOM   10787 C CA  . ARG D 1 320 ? 49.908  -29.105 135.553 1.00 50.50  ? 339 ARG D CA  1 
ATOM   10788 C C   . ARG D 1 320 ? 51.008  -29.777 136.376 1.00 51.45  ? 339 ARG D C   1 
ATOM   10789 O O   . ARG D 1 320 ? 50.708  -30.621 137.225 1.00 50.95  ? 339 ARG D O   1 
ATOM   10790 C CB  . ARG D 1 320 ? 49.338  -27.939 136.369 1.00 51.27  ? 339 ARG D CB  1 
ATOM   10791 C CG  . ARG D 1 320 ? 48.169  -27.125 135.800 1.00 51.57  ? 339 ARG D CG  1 
ATOM   10792 C CD  . ARG D 1 320 ? 47.995  -27.217 134.292 1.00 53.23  ? 339 ARG D CD  1 
ATOM   10793 N NE  . ARG D 1 320 ? 49.136  -26.715 133.533 1.00 56.91  ? 339 ARG D NE  1 
ATOM   10794 C CZ  . ARG D 1 320 ? 49.365  -26.995 132.254 1.00 58.68  ? 339 ARG D CZ  1 
ATOM   10795 N NH1 . ARG D 1 320 ? 48.564  -27.815 131.561 1.00 57.88  ? 339 ARG D NH1 1 
ATOM   10796 N NH2 . ARG D 1 320 ? 50.413  -26.423 131.648 1.00 60.91  ? 339 ARG D NH2 1 
ATOM   10797 N N   . MET D 1 321 ? 52.268  -29.386 136.148 1.00 50.83  ? 340 MET D N   1 
ATOM   10798 C CA  . MET D 1 321 ? 53.368  -30.004 136.879 1.00 51.99  ? 340 MET D CA  1 
ATOM   10799 C C   . MET D 1 321 ? 53.089  -30.099 138.378 1.00 51.40  ? 340 MET D C   1 
ATOM   10800 O O   . MET D 1 321 ? 53.382  -31.122 139.016 1.00 51.36  ? 340 MET D O   1 
ATOM   10801 C CB  . MET D 1 321 ? 54.678  -29.235 136.677 1.00 54.09  ? 340 MET D CB  1 
ATOM   10802 C CG  . MET D 1 321 ? 55.895  -30.057 137.128 1.00 55.51  ? 340 MET D CG  1 
ATOM   10803 S SD  . MET D 1 321 ? 57.457  -29.212 137.129 1.00 58.29  ? 340 MET D SD  1 
ATOM   10804 C CE  . MET D 1 321 ? 57.178  -27.863 138.292 1.00 58.24  ? 340 MET D CE  1 
ATOM   10805 N N   . GLU D 1 322 ? 52.529  -29.047 138.953 1.00 51.25  ? 341 GLU D N   1 
ATOM   10806 C CA  . GLU D 1 322 ? 52.312  -29.003 140.393 1.00 51.26  ? 341 GLU D CA  1 
ATOM   10807 C C   . GLU D 1 322 ? 51.202  -29.922 140.876 1.00 49.46  ? 341 GLU D C   1 
ATOM   10808 O O   . GLU D 1 322 ? 50.947  -29.977 142.082 1.00 49.60  ? 341 GLU D O   1 
ATOM   10809 C CB  . GLU D 1 322 ? 51.993  -27.560 140.798 1.00 52.75  ? 341 GLU D CB  1 
ATOM   10810 C CG  . GLU D 1 322 ? 50.821  -26.966 140.002 1.00 52.60  ? 341 GLU D CG  1 
ATOM   10811 C CD  . GLU D 1 322 ? 51.250  -26.202 138.710 1.00 54.32  ? 341 GLU D CD  1 
ATOM   10812 O OE1 . GLU D 1 322 ? 50.355  -25.529 138.092 1.00 54.12  ? 341 GLU D OE1 1 
ATOM   10813 O OE2 . GLU D 1 322 ? 52.461  -26.287 138.318 1.00 55.81  ? 341 GLU D OE2 1 
ATOM   10814 N N   . ASN D 1 323 ? 50.533  -30.635 139.982 1.00 49.77  ? 342 ASN D N   1 
ATOM   10815 C CA  . ASN D 1 323 ? 49.418  -31.493 140.363 1.00 47.25  ? 342 ASN D CA  1 
ATOM   10816 C C   . ASN D 1 323 ? 49.894  -32.897 140.682 1.00 46.45  ? 342 ASN D C   1 
ATOM   10817 O O   . ASN D 1 323 ? 49.345  -33.864 140.170 1.00 45.07  ? 342 ASN D O   1 
ATOM   10818 C CB  . ASN D 1 323 ? 48.368  -31.553 139.258 1.00 46.46  ? 342 ASN D CB  1 
ATOM   10819 C CG  . ASN D 1 323 ? 47.809  -30.223 138.909 1.00 46.98  ? 342 ASN D CG  1 
ATOM   10820 O OD1 . ASN D 1 323 ? 47.437  -29.992 137.767 1.00 46.90  ? 342 ASN D OD1 1 
ATOM   10821 N ND2 . ASN D 1 323 ? 47.728  -29.345 139.884 1.00 48.10  ? 342 ASN D ND2 1 
ATOM   10822 N N   . GLY D 1 324 ? 50.922  -33.040 141.496 1.00 46.31  ? 343 GLY D N   1 
ATOM   10823 C CA  . GLY D 1 324 ? 51.396  -34.369 141.859 1.00 45.78  ? 343 GLY D CA  1 
ATOM   10824 C C   . GLY D 1 324 ? 52.367  -34.985 140.889 1.00 46.32  ? 343 GLY D C   1 
ATOM   10825 O O   . GLY D 1 324 ? 52.949  -36.025 141.196 1.00 46.11  ? 343 GLY D O   1 
ATOM   10826 N N   . CYS D 1 325 ? 52.597  -34.360 139.739 1.00 47.31  ? 344 CYS D N   1 
ATOM   10827 C CA  . CYS D 1 325 ? 53.274  -35.057 138.650 1.00 48.32  ? 344 CYS D CA  1 
ATOM   10828 C C   . CYS D 1 325 ? 54.680  -35.516 139.029 1.00 49.89  ? 344 CYS D C   1 
ATOM   10829 O O   . CYS D 1 325 ? 55.176  -36.508 138.470 1.00 50.68  ? 344 CYS D O   1 
ATOM   10830 C CB  . CYS D 1 325 ? 53.274  -34.157 137.414 1.00 49.76  ? 344 CYS D CB  1 
ATOM   10831 S SG  . CYS D 1 325 ? 51.562  -33.799 136.797 1.00 47.75  ? 344 CYS D SG  1 
ATOM   10832 N N   . LEU D 1 326 ? 55.312  -34.840 139.986 1.00 48.04  ? 345 LEU D N   1 
ATOM   10833 C CA  . LEU D 1 326 ? 56.666  -35.135 140.431 1.00 49.47  ? 345 LEU D CA  1 
ATOM   10834 C C   . LEU D 1 326 ? 56.698  -35.636 141.862 1.00 49.58  ? 345 LEU D C   1 
ATOM   10835 O O   . LEU D 1 326 ? 57.772  -35.671 142.477 1.00 51.13  ? 345 LEU D O   1 
ATOM   10836 C CB  . LEU D 1 326 ? 57.559  -33.902 140.332 1.00 51.54  ? 345 LEU D CB  1 
ATOM   10837 C CG  . LEU D 1 326 ? 57.689  -33.255 138.963 1.00 52.32  ? 345 LEU D CG  1 
ATOM   10838 C CD1 . LEU D 1 326 ? 58.793  -32.205 139.041 1.00 54.38  ? 345 LEU D CD1 1 
ATOM   10839 C CD2 . LEU D 1 326 ? 57.966  -34.267 137.860 1.00 52.86  ? 345 LEU D CD2 1 
ATOM   10840 N N   . GLU D 1 327 ? 55.550  -35.959 142.437 1.00 47.95  ? 346 GLU D N   1 
ATOM   10841 C CA  . GLU D 1 327 ? 55.577  -36.799 143.623 1.00 48.11  ? 346 GLU D CA  1 
ATOM   10842 C C   . GLU D 1 327 ? 56.147  -38.159 143.237 1.00 47.77  ? 346 GLU D C   1 
ATOM   10843 O O   . GLU D 1 327 ? 56.012  -38.612 142.101 1.00 47.67  ? 346 GLU D O   1 
ATOM   10844 C CB  . GLU D 1 327 ? 54.184  -36.929 144.228 1.00 46.90  ? 346 GLU D CB  1 
ATOM   10845 C CG  . GLU D 1 327 ? 53.554  -35.573 144.582 1.00 47.33  ? 346 GLU D CG  1 
ATOM   10846 C CD  . GLU D 1 327 ? 54.188  -34.954 145.820 1.00 49.22  ? 346 GLU D CD  1 
ATOM   10847 O OE1 . GLU D 1 327 ? 54.382  -35.667 146.817 1.00 49.83  ? 346 GLU D OE1 1 
ATOM   10848 O OE2 . GLU D 1 327 ? 54.502  -33.746 145.802 1.00 50.27  ? 346 GLU D OE2 1 
ATOM   10849 N N   . TRP D 1 328 ? 56.847  -38.775 144.172 1.00 49.43  ? 347 TRP D N   1 
ATOM   10850 C CA  . TRP D 1 328 ? 57.475  -40.071 143.978 1.00 49.33  ? 347 TRP D CA  1 
ATOM   10851 C C   . TRP D 1 328 ? 57.093  -40.941 145.161 1.00 49.21  ? 347 TRP D C   1 
ATOM   10852 O O   . TRP D 1 328 ? 56.811  -40.449 146.265 1.00 49.87  ? 347 TRP D O   1 
ATOM   10853 C CB  . TRP D 1 328 ? 58.985  -39.972 143.865 1.00 51.18  ? 347 TRP D CB  1 
ATOM   10854 C CG  . TRP D 1 328 ? 59.654  -41.107 143.132 1.00 51.15  ? 347 TRP D CG  1 
ATOM   10855 C CD1 . TRP D 1 328 ? 60.618  -41.934 143.634 1.00 52.25  ? 347 TRP D CD1 1 
ATOM   10856 C CD2 . TRP D 1 328 ? 59.447  -41.518 141.760 1.00 50.56  ? 347 TRP D CD2 1 
ATOM   10857 N NE1 . TRP D 1 328 ? 61.005  -42.830 142.673 1.00 51.97  ? 347 TRP D NE1 1 
ATOM   10858 C CE2 . TRP D 1 328 ? 60.304  -42.601 141.519 1.00 51.56  ? 347 TRP D CE2 1 
ATOM   10859 C CE3 . TRP D 1 328 ? 58.625  -41.067 140.716 1.00 50.48  ? 347 TRP D CE3 1 
ATOM   10860 C CZ2 . TRP D 1 328 ? 60.369  -43.245 140.279 1.00 52.31  ? 347 TRP D CZ2 1 
ATOM   10861 C CZ3 . TRP D 1 328 ? 58.695  -41.708 139.473 1.00 51.40  ? 347 TRP D CZ3 1 
ATOM   10862 C CH2 . TRP D 1 328 ? 59.563  -42.784 139.270 1.00 52.40  ? 347 TRP D CH2 1 
ATOM   10863 N N   . TYR D 1 329 ? 57.056  -42.235 144.911 1.00 49.53  ? 348 TYR D N   1 
ATOM   10864 C CA  . TYR D 1 329 ? 56.493  -43.162 145.850 1.00 49.27  ? 348 TYR D CA  1 
ATOM   10865 C C   . TYR D 1 329 ? 57.405  -44.374 145.873 1.00 50.07  ? 348 TYR D C   1 
ATOM   10866 O O   . TYR D 1 329 ? 57.874  -44.812 144.808 1.00 50.08  ? 348 TYR D O   1 
ATOM   10867 C CB  . TYR D 1 329 ? 55.081  -43.599 145.448 1.00 47.29  ? 348 TYR D CB  1 
ATOM   10868 C CG  . TYR D 1 329 ? 54.125  -42.492 145.196 1.00 46.50  ? 348 TYR D CG  1 
ATOM   10869 C CD1 . TYR D 1 329 ? 54.116  -41.809 143.984 1.00 46.08  ? 348 TYR D CD1 1 
ATOM   10870 C CD2 . TYR D 1 329 ? 53.218  -42.123 146.180 1.00 46.51  ? 348 TYR D CD2 1 
ATOM   10871 C CE1 . TYR D 1 329 ? 53.217  -40.769 143.782 1.00 45.51  ? 348 TYR D CE1 1 
ATOM   10872 C CE2 . TYR D 1 329 ? 52.334  -41.115 145.978 1.00 45.96  ? 348 TYR D CE2 1 
ATOM   10873 C CZ  . TYR D 1 329 ? 52.337  -40.446 144.790 1.00 45.37  ? 348 TYR D CZ  1 
ATOM   10874 O OH  . TYR D 1 329 ? 51.420  -39.449 144.639 1.00 45.00  ? 348 TYR D OH  1 
ATOM   10875 N N   . PRO D 1 330 ? 57.630  -44.951 147.056 1.00 51.72  ? 349 PRO D N   1 
ATOM   10876 C CA  . PRO D 1 330 ? 58.601  -46.050 147.171 1.00 52.83  ? 349 PRO D CA  1 
ATOM   10877 C C   . PRO D 1 330 ? 58.315  -47.222 146.253 1.00 51.94  ? 349 PRO D C   1 
ATOM   10878 O O   . PRO D 1 330 ? 59.249  -47.902 145.807 1.00 53.22  ? 349 PRO D O   1 
ATOM   10879 C CB  . PRO D 1 330 ? 58.490  -46.455 148.651 1.00 54.10  ? 349 PRO D CB  1 
ATOM   10880 C CG  . PRO D 1 330 ? 57.217  -45.817 149.180 1.00 53.17  ? 349 PRO D CG  1 
ATOM   10881 C CD  . PRO D 1 330 ? 57.015  -44.592 148.350 1.00 52.22  ? 349 PRO D CD  1 
ATOM   10882 N N   . GLU D 1 331 ? 57.043  -47.467 145.950 1.00 54.79  ? 350 GLU D N   1 
ATOM   10883 C CA  . GLU D 1 331 ? 56.685  -48.556 145.059 1.00 53.98  ? 350 GLU D CA  1 
ATOM   10884 C C   . GLU D 1 331 ? 57.407  -48.469 143.730 1.00 54.93  ? 350 GLU D C   1 
ATOM   10885 O O   . GLU D 1 331 ? 57.637  -49.499 143.067 1.00 55.68  ? 350 GLU D O   1 
ATOM   10886 C CB  . GLU D 1 331 ? 55.182  -48.517 144.823 1.00 52.80  ? 350 GLU D CB  1 
ATOM   10887 C CG  . GLU D 1 331 ? 54.403  -49.165 145.940 1.00 52.35  ? 350 GLU D CG  1 
ATOM   10888 C CD  . GLU D 1 331 ? 53.907  -48.169 147.021 1.00 52.92  ? 350 GLU D CD  1 
ATOM   10889 O OE1 . GLU D 1 331 ? 54.444  -47.007 147.162 1.00 53.13  ? 350 GLU D OE1 1 
ATOM   10890 O OE2 . GLU D 1 331 ? 52.974  -48.607 147.755 1.00 53.12  ? 350 GLU D OE2 1 
ATOM   10891 N N   . PHE D 1 332 ? 57.742  -47.263 143.315 1.00 48.56  ? 351 PHE D N   1 
ATOM   10892 C CA  . PHE D 1 332 ? 58.303  -47.005 142.001 1.00 49.71  ? 351 PHE D CA  1 
ATOM   10893 C C   . PHE D 1 332 ? 59.786  -47.299 141.958 1.00 51.43  ? 351 PHE D C   1 
ATOM   10894 O O   . PHE D 1 332 ? 60.381  -47.235 140.884 1.00 52.87  ? 351 PHE D O   1 
ATOM   10895 C CB  . PHE D 1 332 ? 58.026  -45.559 141.590 1.00 49.98  ? 351 PHE D CB  1 
ATOM   10896 C CG  . PHE D 1 332 ? 56.560  -45.264 141.365 1.00 48.08  ? 351 PHE D CG  1 
ATOM   10897 C CD1 . PHE D 1 332 ? 55.600  -46.252 141.493 1.00 46.35  ? 351 PHE D CD1 1 
ATOM   10898 C CD2 . PHE D 1 332 ? 56.128  -43.979 141.004 1.00 48.37  ? 351 PHE D CD2 1 
ATOM   10899 C CE1 . PHE D 1 332 ? 54.242  -45.964 141.275 1.00 45.01  ? 351 PHE D CE1 1 
ATOM   10900 C CE2 . PHE D 1 332 ? 54.772  -43.690 140.800 1.00 46.55  ? 351 PHE D CE2 1 
ATOM   10901 C CZ  . PHE D 1 332 ? 53.841  -44.669 140.945 1.00 44.88  ? 351 PHE D CZ  1 
ATOM   10902 N N   . ASP D 1 333 ? 60.380  -47.642 143.095 1.00 50.13  ? 352 ASP D N   1 
ATOM   10903 C CA  . ASP D 1 333 ? 61.800  -47.963 143.184 1.00 52.19  ? 352 ASP D CA  1 
ATOM   10904 C C   . ASP D 1 333 ? 62.050  -49.430 143.473 1.00 52.69  ? 352 ASP D C   1 
ATOM   10905 O O   . ASP D 1 333 ? 63.190  -49.894 143.333 1.00 54.31  ? 352 ASP D O   1 
ATOM   10906 C CB  . ASP D 1 333 ? 62.477  -47.137 144.284 1.00 53.99  ? 352 ASP D CB  1 
ATOM   10907 C CG  . ASP D 1 333 ? 62.485  -45.644 143.982 1.00 53.98  ? 352 ASP D CG  1 
ATOM   10908 O OD1 . ASP D 1 333 ? 62.350  -45.262 142.795 1.00 54.28  ? 352 ASP D OD1 1 
ATOM   10909 O OD2 . ASP D 1 333 ? 62.624  -44.862 144.937 1.00 54.89  ? 352 ASP D OD2 1 
ATOM   10910 N N   . LYS D 1 334 ? 61.011  -50.162 143.865 1.00 53.10  ? 353 LYS D N   1 
ATOM   10911 C CA  . LYS D 1 334 ? 61.186  -51.537 144.263 1.00 53.72  ? 353 LYS D CA  1 
ATOM   10912 C C   . LYS D 1 334 ? 61.413  -52.418 143.048 1.00 53.85  ? 353 LYS D C   1 
ATOM   10913 O O   . LYS D 1 334 ? 60.821  -52.176 141.991 1.00 53.28  ? 353 LYS D O   1 
ATOM   10914 C CB  . LYS D 1 334 ? 59.960  -52.013 145.027 1.00 52.76  ? 353 LYS D CB  1 
ATOM   10915 C CG  . LYS D 1 334 ? 59.817  -51.283 146.332 1.00 53.53  ? 353 LYS D CG  1 
ATOM   10916 C CD  . LYS D 1 334 ? 58.527  -51.585 147.045 1.00 53.17  ? 353 LYS D CD  1 
ATOM   10917 C CE  . LYS D 1 334 ? 58.597  -50.980 148.448 1.00 53.93  ? 353 LYS D CE  1 
ATOM   10918 N NZ  . LYS D 1 334 ? 57.278  -50.344 148.838 1.00 52.31  ? 353 LYS D NZ  1 
ATOM   10919 N N   . PRO D 1 335 ? 62.242  -53.447 143.171 1.00 53.49  ? 354 PRO D N   1 
ATOM   10920 C CA  . PRO D 1 335 ? 62.368  -54.445 142.107 1.00 53.21  ? 354 PRO D CA  1 
ATOM   10921 C C   . PRO D 1 335 ? 61.037  -55.044 141.751 1.00 51.17  ? 354 PRO D C   1 
ATOM   10922 O O   . PRO D 1 335 ? 60.258  -55.451 142.617 1.00 50.76  ? 354 PRO D O   1 
ATOM   10923 C CB  . PRO D 1 335 ? 63.295  -55.496 142.712 1.00 55.27  ? 354 PRO D CB  1 
ATOM   10924 C CG  . PRO D 1 335 ? 64.109  -54.729 143.675 1.00 57.04  ? 354 PRO D CG  1 
ATOM   10925 C CD  . PRO D 1 335 ? 63.156  -53.730 144.290 1.00 55.74  ? 354 PRO D CD  1 
ATOM   10926 N N   . LEU D 1 336 ? 60.795  -55.105 140.446 1.00 51.07  ? 355 LEU D N   1 
ATOM   10927 C CA  . LEU D 1 336 ? 59.585  -55.701 139.889 1.00 49.32  ? 355 LEU D CA  1 
ATOM   10928 C C   . LEU D 1 336 ? 59.961  -56.943 139.086 1.00 49.80  ? 355 LEU D C   1 
ATOM   10929 O O   . LEU D 1 336 ? 59.569  -58.059 139.459 1.00 49.80  ? 355 LEU D O   1 
ATOM   10930 C CB  . LEU D 1 336 ? 58.872  -54.656 139.046 1.00 48.06  ? 355 LEU D CB  1 
ATOM   10931 C CG  . LEU D 1 336 ? 57.557  -55.108 138.407 1.00 46.52  ? 355 LEU D CG  1 
ATOM   10932 C CD1 . LEU D 1 336 ? 56.518  -55.429 139.482 1.00 45.32  ? 355 LEU D CD1 1 
ATOM   10933 C CD2 . LEU D 1 336 ? 57.082  -54.045 137.440 1.00 46.19  ? 355 LEU D CD2 1 
ATOM   10934 N N   . GLY D 1 337 ? 60.688  -56.787 137.973 1.00 49.82  ? 356 GLY D N   1 
ATOM   10935 C CA  . GLY D 1 337 ? 61.166  -57.907 137.197 1.00 50.50  ? 356 GLY D CA  1 
ATOM   10936 C C   . GLY D 1 337 ? 60.147  -58.392 136.179 1.00 48.87  ? 356 GLY D C   1 
ATOM   10937 O O   . GLY D 1 337 ? 58.982  -57.976 136.151 1.00 47.21  ? 356 GLY D O   1 
ATOM   10938 N N   . LYS D 1 338 ? 60.611  -59.291 135.319 1.00 48.95  ? 357 LYS D N   1 
ATOM   10939 C CA  . LYS D 1 338 ? 59.758  -59.791 134.257 1.00 48.26  ? 357 LYS D CA  1 
ATOM   10940 C C   . LYS D 1 338 ? 58.519  -60.433 134.879 1.00 46.57  ? 357 LYS D C   1 
ATOM   10941 O O   . LYS D 1 338 ? 58.611  -61.018 135.980 1.00 47.31  ? 357 LYS D O   1 
ATOM   10942 C CB  . LYS D 1 338 ? 60.547  -60.783 133.393 1.00 50.91  ? 357 LYS D CB  1 
ATOM   10943 N N   . PRO D 1 339 ? 57.345  -60.299 134.255 1.00 47.17  ? 358 PRO D N   1 
ATOM   10944 C CA  . PRO D 1 339 ? 56.195  -61.114 134.655 1.00 45.94  ? 358 PRO D CA  1 
ATOM   10945 C C   . PRO D 1 339 ? 56.508  -62.592 134.516 1.00 47.15  ? 358 PRO D C   1 
ATOM   10946 O O   . PRO D 1 339 ? 57.110  -63.034 133.525 1.00 48.47  ? 358 PRO D O   1 
ATOM   10947 C CB  . PRO D 1 339 ? 55.096  -60.706 133.667 1.00 45.02  ? 358 PRO D CB  1 
ATOM   10948 C CG  . PRO D 1 339 ? 55.499  -59.414 133.120 1.00 45.88  ? 358 PRO D CG  1 
ATOM   10949 C CD  . PRO D 1 339 ? 57.003  -59.325 133.211 1.00 47.33  ? 358 PRO D CD  1 
ATOM   10950 N N   . VAL D 1 340 ? 56.071  -63.372 135.496 1.00 45.82  ? 359 VAL D N   1 
ATOM   10951 C CA  . VAL D 1 340 ? 56.370  -64.796 135.481 1.00 47.08  ? 359 VAL D CA  1 
ATOM   10952 C C   . VAL D 1 340 ? 55.123  -65.632 135.255 1.00 46.31  ? 359 VAL D C   1 
ATOM   10953 O O   . VAL D 1 340 ? 55.154  -66.839 135.437 1.00 47.39  ? 359 VAL D O   1 
ATOM   10954 C CB  . VAL D 1 340 ? 57.090  -65.223 136.766 1.00 48.71  ? 359 VAL D CB  1 
ATOM   10955 C CG1 . VAL D 1 340 ? 58.347  -64.394 136.975 1.00 50.06  ? 359 VAL D CG1 1 
ATOM   10956 C CG2 . VAL D 1 340 ? 56.150  -65.065 137.945 1.00 48.11  ? 359 VAL D CG2 1 
ATOM   10957 N N   . GLY D 1 341 ? 54.025  -65.017 134.890 1.00 47.70  ? 360 GLY D N   1 
ATOM   10958 C CA  . GLY D 1 341 ? 52.862  -65.755 134.446 1.00 46.56  ? 360 GLY D CA  1 
ATOM   10959 C C   . GLY D 1 341 ? 51.915  -64.758 133.827 1.00 45.06  ? 360 GLY D C   1 
ATOM   10960 O O   . GLY D 1 341 ? 52.126  -63.547 133.903 1.00 44.98  ? 360 GLY D O   1 
ATOM   10961 N N   . GLU D 1 342 ? 50.888  -65.274 133.169 1.00 46.54  ? 361 GLU D N   1 
ATOM   10962 C CA  . GLU D 1 342 ? 49.907  -64.367 132.595 1.00 45.56  ? 361 GLU D CA  1 
ATOM   10963 C C   . GLU D 1 342 ? 48.924  -63.930 133.680 1.00 44.30  ? 361 GLU D C   1 
ATOM   10964 O O   . GLU D 1 342 ? 48.879  -64.475 134.787 1.00 44.61  ? 361 GLU D O   1 
ATOM   10965 C CB  . GLU D 1 342 ? 49.174  -65.018 131.439 1.00 45.97  ? 361 GLU D CB  1 
ATOM   10966 C CG  . GLU D 1 342 ? 50.074  -65.371 130.287 1.00 47.59  ? 361 GLU D CG  1 
ATOM   10967 C CD  . GLU D 1 342 ? 50.440  -64.191 129.399 1.00 48.62  ? 361 GLU D CD  1 
ATOM   10968 O OE1 . GLU D 1 342 ? 50.041  -63.015 129.678 1.00 47.76  ? 361 GLU D OE1 1 
ATOM   10969 O OE2 . GLU D 1 342 ? 51.144  -64.446 128.395 1.00 50.64  ? 361 GLU D OE2 1 
ATOM   10970 N N   . MET D 1 343 ? 48.157  -62.905 133.363 1.00 42.35  ? 362 MET D N   1 
ATOM   10971 C CA  . MET D 1 343 ? 47.132  -62.448 134.280 1.00 41.62  ? 362 MET D CA  1 
ATOM   10972 C C   . MET D 1 343 ? 46.102  -63.550 134.447 1.00 42.02  ? 362 MET D C   1 
ATOM   10973 O O   . MET D 1 343 ? 45.705  -64.193 133.488 1.00 42.53  ? 362 MET D O   1 
ATOM   10974 C CB  . MET D 1 343 ? 46.476  -61.178 133.727 1.00 40.90  ? 362 MET D CB  1 
ATOM   10975 C CG  . MET D 1 343 ? 45.513  -60.514 134.663 1.00 40.08  ? 362 MET D CG  1 
ATOM   10976 S SD  . MET D 1 343 ? 44.770  -59.021 133.929 1.00 39.53  ? 362 MET D SD  1 
ATOM   10977 C CE  . MET D 1 343 ? 43.534  -59.635 132.782 1.00 40.14  ? 362 MET D CE  1 
ATOM   10978 N N   . VAL D 1 344 ? 45.646  -63.747 135.665 1.00 38.47  ? 363 VAL D N   1 
ATOM   10979 C CA  . VAL D 1 344 ? 44.669  -64.775 135.976 1.00 38.96  ? 363 VAL D CA  1 
ATOM   10980 C C   . VAL D 1 344 ? 43.444  -64.071 136.506 1.00 38.24  ? 363 VAL D C   1 
ATOM   10981 O O   . VAL D 1 344 ? 43.522  -63.372 137.529 1.00 38.21  ? 363 VAL D O   1 
ATOM   10982 C CB  . VAL D 1 344 ? 45.213  -65.793 136.990 1.00 40.42  ? 363 VAL D CB  1 
ATOM   10983 C CG1 . VAL D 1 344 ? 44.180  -66.830 137.339 1.00 41.16  ? 363 VAL D CG1 1 
ATOM   10984 C CG2 . VAL D 1 344 ? 46.471  -66.396 136.418 1.00 41.17  ? 363 VAL D CG2 1 
ATOM   10985 N N   . ARG D 1 345 ? 42.326  -64.219 135.793 1.00 39.71  ? 364 ARG D N   1 
ATOM   10986 C CA  . ARG D 1 345 ? 41.085  -63.554 136.161 1.00 40.03  ? 364 ARG D CA  1 
ATOM   10987 C C   . ARG D 1 345 ? 40.162  -64.545 136.854 1.00 41.16  ? 364 ARG D C   1 
ATOM   10988 O O   . ARG D 1 345 ? 40.135  -65.746 136.567 1.00 42.05  ? 364 ARG D O   1 
ATOM   10989 C CB  . ARG D 1 345 ? 40.348  -62.952 134.957 1.00 40.39  ? 364 ARG D CB  1 
ATOM   10990 C CG  . ARG D 1 345 ? 38.884  -62.527 135.273 1.00 41.08  ? 364 ARG D CG  1 
ATOM   10991 C CD  . ARG D 1 345 ? 38.410  -61.333 134.463 1.00 40.38  ? 364 ARG D CD  1 
ATOM   10992 N NE  . ARG D 1 345 ? 37.663  -61.685 133.264 1.00 40.10  ? 364 ARG D NE  1 
ATOM   10993 C CZ  . ARG D 1 345 ? 36.351  -61.557 133.149 1.00 39.70  ? 364 ARG D CZ  1 
ATOM   10994 N NH1 . ARG D 1 345 ? 35.570  -61.342 134.204 1.00 39.54  ? 364 ARG D NH1 1 
ATOM   10995 N NH2 . ARG D 1 345 ? 35.811  -61.615 131.944 1.00 39.05  ? 364 ARG D NH2 1 
ATOM   10996 N N   . ASP D 1 346 ? 39.352  -63.995 137.754 1.00 41.26  ? 365 ASP D N   1 
ATOM   10997 C CA  . ASP D 1 346 ? 38.432  -64.754 138.580 1.00 42.76  ? 365 ASP D CA  1 
ATOM   10998 C C   . ASP D 1 346 ? 37.273  -63.781 138.834 1.00 42.58  ? 365 ASP D C   1 
ATOM   10999 O O   . ASP D 1 346 ? 37.226  -63.061 139.831 1.00 42.10  ? 365 ASP D O   1 
ATOM   11000 C CB  . ASP D 1 346 ? 39.098  -65.217 139.873 1.00 44.10  ? 365 ASP D CB  1 
ATOM   11001 C CG  . ASP D 1 346 ? 38.121  -65.773 140.832 1.00 45.90  ? 365 ASP D CG  1 
ATOM   11002 O OD1 . ASP D 1 346 ? 38.503  -66.126 141.974 1.00 47.61  ? 365 ASP D OD1 1 
ATOM   11003 O OD2 . ASP D 1 346 ? 36.946  -65.885 140.426 1.00 45.88  ? 365 ASP D OD2 1 
ATOM   11004 N N   . GLY D 1 347 ? 36.356  -63.739 137.886 1.00 43.33  ? 366 GLY D N   1 
ATOM   11005 C CA  . GLY D 1 347 ? 35.275  -62.756 137.961 1.00 41.95  ? 366 GLY D CA  1 
ATOM   11006 C C   . GLY D 1 347 ? 35.854  -61.356 137.857 1.00 40.88  ? 366 GLY D C   1 
ATOM   11007 O O   . GLY D 1 347 ? 36.483  -60.982 136.851 1.00 40.71  ? 366 GLY D O   1 
ATOM   11008 N N   . TRP D 1 348 ? 35.631  -60.559 138.910 1.00 42.92  ? 367 TRP D N   1 
ATOM   11009 C CA  . TRP D 1 348 ? 36.150  -59.188 139.014 1.00 41.50  ? 367 TRP D CA  1 
ATOM   11010 C C   . TRP D 1 348 ? 37.518  -59.135 139.689 1.00 41.95  ? 367 TRP D C   1 
ATOM   11011 O O   . TRP D 1 348 ? 38.073  -58.045 139.839 1.00 40.87  ? 367 TRP D O   1 
ATOM   11012 C CB  . TRP D 1 348 ? 35.162  -58.268 139.785 1.00 41.00  ? 367 TRP D CB  1 
ATOM   11013 C CG  . TRP D 1 348 ? 33.766  -58.322 139.225 1.00 40.74  ? 367 TRP D CG  1 
ATOM   11014 C CD1 . TRP D 1 348 ? 32.664  -58.836 139.825 1.00 42.45  ? 367 TRP D CD1 1 
ATOM   11015 C CD2 . TRP D 1 348 ? 33.335  -57.840 137.940 1.00 39.57  ? 367 TRP D CD2 1 
ATOM   11016 N NE1 . TRP D 1 348 ? 31.576  -58.754 138.976 1.00 42.39  ? 367 TRP D NE1 1 
ATOM   11017 C CE2 . TRP D 1 348 ? 31.963  -58.122 137.825 1.00 40.44  ? 367 TRP D CE2 1 
ATOM   11018 C CE3 . TRP D 1 348 ? 33.976  -57.179 136.882 1.00 38.31  ? 367 TRP D CE3 1 
ATOM   11019 C CZ2 . TRP D 1 348 ? 31.231  -57.778 136.704 1.00 39.83  ? 367 TRP D CZ2 1 
ATOM   11020 C CZ3 . TRP D 1 348 ? 33.243  -56.866 135.758 1.00 37.40  ? 367 TRP D CZ3 1 
ATOM   11021 C CH2 . TRP D 1 348 ? 31.889  -57.161 135.684 1.00 38.12  ? 367 TRP D CH2 1 
ATOM   11022 N N   . LYS D 1 349 ? 38.071  -60.290 140.078 1.00 40.92  ? 368 LYS D N   1 
ATOM   11023 C CA  . LYS D 1 349 ? 39.392  -60.399 140.701 1.00 41.39  ? 368 LYS D CA  1 
ATOM   11024 C C   . LYS D 1 349 ? 40.454  -60.683 139.653 1.00 40.58  ? 368 LYS D C   1 
ATOM   11025 O O   . LYS D 1 349 ? 40.209  -61.386 138.680 1.00 41.27  ? 368 LYS D O   1 
ATOM   11026 C CB  . LYS D 1 349 ? 39.359  -61.514 141.738 1.00 43.38  ? 368 LYS D CB  1 
ATOM   11027 C CG  . LYS D 1 349 ? 38.487  -61.193 142.948 1.00 44.75  ? 368 LYS D CG  1 
ATOM   11028 C CD  . LYS D 1 349 ? 38.027  -62.449 143.683 1.00 47.15  ? 368 LYS D CD  1 
ATOM   11029 C CE  . LYS D 1 349 ? 37.484  -62.127 145.062 1.00 48.52  ? 368 LYS D CE  1 
ATOM   11030 N NZ  . LYS D 1 349 ? 37.846  -63.230 146.067 1.00 50.41  ? 368 LYS D NZ  1 
ATOM   11031 N N   . LEU D 1 350 ? 41.628  -60.095 139.827 1.00 39.87  ? 369 LEU D N   1 
ATOM   11032 C CA  . LEU D 1 350 ? 42.704  -60.282 138.867 1.00 39.31  ? 369 LEU D CA  1 
ATOM   11033 C C   . LEU D 1 350 ? 43.963  -60.537 139.672 1.00 39.95  ? 369 LEU D C   1 
ATOM   11034 O O   . LEU D 1 350 ? 44.118  -60.007 140.763 1.00 40.11  ? 369 LEU D O   1 
ATOM   11035 C CB  . LEU D 1 350 ? 42.944  -59.078 137.950 1.00 38.66  ? 369 LEU D CB  1 
ATOM   11036 C CG  . LEU D 1 350 ? 41.750  -58.488 137.226 1.00 38.64  ? 369 LEU D CG  1 
ATOM   11037 C CD1 . LEU D 1 350 ? 42.043  -57.128 136.543 1.00 37.86  ? 369 LEU D CD1 1 
ATOM   11038 C CD2 . LEU D 1 350 ? 41.215  -59.494 136.200 1.00 39.60  ? 369 LEU D CD2 1 
ATOM   11039 N N   . SER D 1 351 ? 44.868  -61.337 139.130 1.00 38.76  ? 370 SER D N   1 
ATOM   11040 C CA  . SER D 1 351 ? 46.119  -61.543 139.833 1.00 39.76  ? 370 SER D CA  1 
ATOM   11041 C C   . SER D 1 351 ? 47.211  -61.703 138.797 1.00 39.69  ? 370 SER D C   1 
ATOM   11042 O O   . SER D 1 351 ? 46.964  -62.080 137.652 1.00 39.17  ? 370 SER D O   1 
ATOM   11043 C CB  . SER D 1 351 ? 46.048  -62.752 140.769 1.00 41.20  ? 370 SER D CB  1 
ATOM   11044 O OG  . SER D 1 351 ? 45.810  -63.965 140.066 1.00 41.85  ? 370 SER D OG  1 
ATOM   11045 N N   . ARG D 1 352 ? 48.429  -61.405 139.224 1.00 41.49  ? 371 ARG D N   1 
ATOM   11046 C CA  . ARG D 1 352 ? 49.585  -61.433 138.342 1.00 41.97  ? 371 ARG D CA  1 
ATOM   11047 C C   . ARG D 1 352 ? 50.814  -61.597 139.211 1.00 43.01  ? 371 ARG D C   1 
ATOM   11048 O O   . ARG D 1 352 ? 50.970  -60.848 140.183 1.00 43.14  ? 371 ARG D O   1 
ATOM   11049 C CB  . ARG D 1 352 ? 49.689  -60.146 137.523 1.00 41.81  ? 371 ARG D CB  1 
ATOM   11050 C CG  . ARG D 1 352 ? 50.701  -60.206 136.415 1.00 42.28  ? 371 ARG D CG  1 
ATOM   11051 C CD  . ARG D 1 352 ? 50.157  -60.965 135.209 1.00 42.24  ? 371 ARG D CD  1 
ATOM   11052 N NE  . ARG D 1 352 ? 51.031  -60.847 134.046 1.00 43.03  ? 371 ARG D NE  1 
ATOM   11053 C CZ  . ARG D 1 352 ? 51.220  -59.729 133.357 1.00 42.92  ? 371 ARG D CZ  1 
ATOM   11054 N NH1 . ARG D 1 352 ? 50.605  -58.607 133.680 1.00 41.82  ? 371 ARG D NH1 1 
ATOM   11055 N NH2 . ARG D 1 352 ? 52.039  -59.740 132.314 1.00 44.41  ? 371 ARG D NH2 1 
ATOM   11056 N N   . GLU D 1 353 ? 51.685  -62.538 138.844 1.00 44.05  ? 372 GLU D N   1 
ATOM   11057 C CA  . GLU D 1 353 ? 52.972  -62.736 139.486 1.00 45.30  ? 372 GLU D CA  1 
ATOM   11058 C C   . GLU D 1 353 ? 54.102  -62.102 138.675 1.00 46.15  ? 372 GLU D C   1 
ATOM   11059 O O   . GLU D 1 353 ? 54.198  -62.323 137.466 1.00 46.45  ? 372 GLU D O   1 
ATOM   11060 C CB  . GLU D 1 353 ? 53.231  -64.243 139.656 1.00 46.64  ? 372 GLU D CB  1 
ATOM   11061 C CG  . GLU D 1 353 ? 52.218  -64.962 140.534 1.00 47.58  ? 372 GLU D CG  1 
ATOM   11062 C CD  . GLU D 1 353 ? 52.151  -64.353 141.939 1.00 48.61  ? 372 GLU D CD  1 
ATOM   11063 O OE1 . GLU D 1 353 ? 53.233  -64.029 142.523 1.00 49.29  ? 372 GLU D OE1 1 
ATOM   11064 O OE2 . GLU D 1 353 ? 51.008  -64.158 142.433 1.00 48.97  ? 372 GLU D OE2 1 
ATOM   11065 N N   . TYR D 1 354 ? 54.972  -61.347 139.356 1.00 45.36  ? 373 TYR D N   1 
ATOM   11066 C CA  . TYR D 1 354 ? 56.230  -60.837 138.819 1.00 46.02  ? 373 TYR D CA  1 
ATOM   11067 C C   . TYR D 1 354 ? 57.395  -61.521 139.534 1.00 48.10  ? 373 TYR D C   1 
ATOM   11068 O O   . TYR D 1 354 ? 57.230  -62.092 140.617 1.00 48.94  ? 373 TYR D O   1 
ATOM   11069 C CB  . TYR D 1 354 ? 56.307  -59.298 138.976 1.00 45.36  ? 373 TYR D CB  1 
ATOM   11070 C CG  . TYR D 1 354 ? 55.352  -58.555 138.053 1.00 43.57  ? 373 TYR D CG  1 
ATOM   11071 C CD1 . TYR D 1 354 ? 53.985  -58.518 138.314 1.00 42.33  ? 373 TYR D CD1 1 
ATOM   11072 C CD2 . TYR D 1 354 ? 55.815  -57.941 136.895 1.00 43.83  ? 373 TYR D CD2 1 
ATOM   11073 C CE1 . TYR D 1 354 ? 53.131  -57.860 137.480 1.00 40.90  ? 373 TYR D CE1 1 
ATOM   11074 C CE2 . TYR D 1 354 ? 54.964  -57.290 136.044 1.00 43.17  ? 373 TYR D CE2 1 
ATOM   11075 C CZ  . TYR D 1 354 ? 53.614  -57.249 136.343 1.00 41.18  ? 373 TYR D CZ  1 
ATOM   11076 O OH  . TYR D 1 354 ? 52.724  -56.615 135.487 1.00 40.48  ? 373 TYR D OH  1 
ATOM   11077 N N   . LYS D 1 355 ? 58.590  -61.468 138.924 1.00 46.29  ? 374 LYS D N   1 
ATOM   11078 C CA  . LYS D 1 355 ? 59.740  -62.132 139.543 1.00 48.57  ? 374 LYS D CA  1 
ATOM   11079 C C   . LYS D 1 355 ? 59.917  -61.660 140.979 1.00 49.56  ? 374 LYS D C   1 
ATOM   11080 O O   . LYS D 1 355 ? 60.198  -62.459 141.866 1.00 50.76  ? 374 LYS D O   1 
ATOM   11081 C CB  . LYS D 1 355 ? 61.038  -61.903 138.758 1.00 51.18  ? 374 LYS D CB  1 
ATOM   11082 N N   . HIS D 1 356 ? 59.729  -60.372 141.242 1.00 48.67  ? 375 HIS D N   1 
ATOM   11083 C CA  . HIS D 1 356 ? 59.944  -59.864 142.593 1.00 50.23  ? 375 HIS D CA  1 
ATOM   11084 C C   . HIS D 1 356 ? 58.675  -59.365 143.267 1.00 49.27  ? 375 HIS D C   1 
ATOM   11085 O O   . HIS D 1 356 ? 58.763  -58.729 144.326 1.00 50.53  ? 375 HIS D O   1 
ATOM   11086 C CB  . HIS D 1 356 ? 60.988  -58.735 142.601 1.00 52.16  ? 375 HIS D CB  1 
ATOM   11087 C CG  . HIS D 1 356 ? 62.304  -59.122 142.006 1.00 53.62  ? 375 HIS D CG  1 
ATOM   11088 N ND1 . HIS D 1 356 ? 63.064  -60.179 142.470 1.00 55.38  ? 375 HIS D ND1 1 
ATOM   11089 C CD2 . HIS D 1 356 ? 62.997  -58.587 140.976 1.00 54.51  ? 375 HIS D CD2 1 
ATOM   11090 C CE1 . HIS D 1 356 ? 64.164  -60.281 141.746 1.00 56.29  ? 375 HIS D CE1 1 
ATOM   11091 N NE2 . HIS D 1 356 ? 64.142  -59.331 140.826 1.00 56.30  ? 375 HIS D NE2 1 
ATOM   11092 N N   . ALA D 1 357 ? 57.501  -59.653 142.714 1.00 49.22  ? 376 ALA D N   1 
ATOM   11093 C CA  . ALA D 1 357 ? 56.291  -59.128 143.333 1.00 48.53  ? 376 ALA D CA  1 
ATOM   11094 C C   . ALA D 1 357 ? 55.066  -59.948 142.952 1.00 47.14  ? 376 ALA D C   1 
ATOM   11095 O O   . ALA D 1 357 ? 55.011  -60.613 141.911 1.00 46.22  ? 376 ALA D O   1 
ATOM   11096 C CB  . ALA D 1 357 ? 56.065  -57.652 142.962 1.00 49.05  ? 376 ALA D CB  1 
ATOM   11097 N N   . SER D 1 358 ? 54.068  -59.866 143.822 1.00 48.50  ? 377 SER D N   1 
ATOM   11098 C CA  . SER D 1 358 ? 52.830  -60.610 143.674 1.00 47.12  ? 377 SER D CA  1 
ATOM   11099 C C   . SER D 1 358 ? 51.656  -59.644 143.819 1.00 46.38  ? 377 SER D C   1 
ATOM   11100 O O   . SER D 1 358 ? 51.569  -58.897 144.799 1.00 47.77  ? 377 SER D O   1 
ATOM   11101 C CB  . SER D 1 358 ? 52.792  -61.747 144.688 1.00 48.58  ? 377 SER D CB  1 
ATOM   11102 O OG  . SER D 1 358 ? 51.536  -62.373 144.603 1.00 48.45  ? 377 SER D OG  1 
ATOM   11103 N N   . VAL D 1 359 ? 50.774  -59.639 142.818 1.00 43.87  ? 378 VAL D N   1 
ATOM   11104 C CA  . VAL D 1 359 ? 49.734  -58.634 142.680 1.00 43.49  ? 378 VAL D CA  1 
ATOM   11105 C C   . VAL D 1 359 ? 48.382  -59.316 142.667 1.00 42.54  ? 378 VAL D C   1 
ATOM   11106 O O   . VAL D 1 359 ? 48.147  -60.212 141.851 1.00 41.20  ? 378 VAL D O   1 
ATOM   11107 C CB  . VAL D 1 359 ? 49.932  -57.823 141.384 1.00 42.58  ? 378 VAL D CB  1 
ATOM   11108 C CG1 . VAL D 1 359 ? 48.840  -56.819 141.190 1.00 41.78  ? 378 VAL D CG1 1 
ATOM   11109 C CG2 . VAL D 1 359 ? 51.291  -57.156 141.392 1.00 44.55  ? 378 VAL D CG2 1 
ATOM   11110 N N   . ARG D 1 360 ? 47.489  -58.876 143.543 1.00 40.18  ? 379 ARG D N   1 
ATOM   11111 C CA  . ARG D 1 360 ? 46.082  -59.255 143.508 1.00 39.66  ? 379 ARG D CA  1 
ATOM   11112 C C   . ARG D 1 360 ? 45.259  -57.974 143.586 1.00 39.85  ? 379 ARG D C   1 
ATOM   11113 O O   . ARG D 1 360 ? 45.633  -57.039 144.303 1.00 41.11  ? 379 ARG D O   1 
ATOM   11114 C CB  . ARG D 1 360 ? 45.727  -60.222 144.653 1.00 42.30  ? 379 ARG D CB  1 
ATOM   11115 N N   . VAL D 1 361 ? 44.170  -57.898 142.805 1.00 41.39  ? 380 VAL D N   1 
ATOM   11116 C CA  . VAL D 1 361 ? 43.215  -56.793 142.895 1.00 41.95  ? 380 VAL D CA  1 
ATOM   11117 C C   . VAL D 1 361 ? 41.798  -57.320 142.700 1.00 41.28  ? 380 VAL D C   1 
ATOM   11118 O O   . VAL D 1 361 ? 41.581  -58.333 142.026 1.00 40.02  ? 380 VAL D O   1 
ATOM   11119 C CB  . VAL D 1 361 ? 43.493  -55.676 141.864 1.00 40.62  ? 380 VAL D CB  1 
ATOM   11120 C CG1 . VAL D 1 361 ? 43.448  -56.224 140.428 1.00 38.23  ? 380 VAL D CG1 1 
ATOM   11121 C CG2 . VAL D 1 361 ? 42.453  -54.614 141.927 1.00 40.22  ? 380 VAL D CG2 1 
ATOM   11122 N N   . ASP D 1 362 ? 40.827  -56.594 143.279 1.00 41.69  ? 381 ASP D N   1 
ATOM   11123 C CA  . ASP D 1 362 ? 39.400  -56.927 143.207 1.00 41.61  ? 381 ASP D CA  1 
ATOM   11124 C C   . ASP D 1 362 ? 38.627  -55.705 142.706 1.00 40.33  ? 381 ASP D C   1 
ATOM   11125 O O   . ASP D 1 362 ? 38.362  -54.763 143.462 1.00 41.70  ? 381 ASP D O   1 
ATOM   11126 C CB  . ASP D 1 362 ? 38.888  -57.383 144.565 1.00 44.36  ? 381 ASP D CB  1 
ATOM   11127 C CG  . ASP D 1 362 ? 37.459  -57.820 144.528 1.00 45.38  ? 381 ASP D CG  1 
ATOM   11128 O OD1 . ASP D 1 362 ? 36.728  -57.417 143.601 1.00 44.42  ? 381 ASP D OD1 1 
ATOM   11129 O OD2 . ASP D 1 362 ? 37.049  -58.592 145.421 1.00 47.22  ? 381 ASP D OD2 1 
ATOM   11130 N N   . LEU D 1 363 ? 38.230  -55.734 141.444 1.00 39.06  ? 382 LEU D N   1 
ATOM   11131 C CA  . LEU D 1 363 ? 37.583  -54.559 140.876 1.00 37.94  ? 382 LEU D CA  1 
ATOM   11132 C C   . LEU D 1 363 ? 36.233  -54.262 141.518 1.00 40.08  ? 382 LEU D C   1 
ATOM   11133 O O   . LEU D 1 363 ? 35.753  -53.127 141.438 1.00 39.86  ? 382 LEU D O   1 
ATOM   11134 C CB  . LEU D 1 363 ? 37.418  -54.763 139.370 1.00 37.33  ? 382 LEU D CB  1 
ATOM   11135 C CG  . LEU D 1 363 ? 38.753  -54.961 138.659 1.00 36.91  ? 382 LEU D CG  1 
ATOM   11136 C CD1 . LEU D 1 363 ? 38.518  -55.234 137.207 1.00 37.29  ? 382 LEU D CD1 1 
ATOM   11137 C CD2 . LEU D 1 363 ? 39.708  -53.792 138.855 1.00 37.00  ? 382 LEU D CD2 1 
ATOM   11138 N N   . GLU D 1 364 ? 35.603  -55.262 142.144 1.00 40.00  ? 383 GLU D N   1 
ATOM   11139 C CA  . GLU D 1 364 ? 34.263  -55.049 142.675 1.00 42.86  ? 383 GLU D CA  1 
ATOM   11140 C C   . GLU D 1 364 ? 34.293  -54.329 144.002 1.00 45.53  ? 383 GLU D C   1 
ATOM   11141 O O   . GLU D 1 364 ? 33.376  -53.581 144.311 1.00 46.47  ? 383 GLU D O   1 
ATOM   11142 C CB  . GLU D 1 364 ? 33.540  -56.377 142.858 1.00 44.40  ? 383 GLU D CB  1 
ATOM   11143 C CG  . GLU D 1 364 ? 32.023  -56.212 143.073 1.00 46.48  ? 383 GLU D CG  1 
ATOM   11144 C CD  . GLU D 1 364 ? 31.229  -57.540 143.069 1.00 47.71  ? 383 GLU D CD  1 
ATOM   11145 O OE1 . GLU D 1 364 ? 31.830  -58.614 143.347 1.00 46.52  ? 383 GLU D OE1 1 
ATOM   11146 O OE2 . GLU D 1 364 ? 29.997  -57.484 142.800 1.00 49.63  ? 383 GLU D OE2 1 
ATOM   11147 N N   . SER D 1 365 ? 35.327  -54.549 144.785 1.00 43.86  ? 384 SER D N   1 
ATOM   11148 C CA  . SER D 1 365 ? 35.464  -53.969 146.104 1.00 45.01  ? 384 SER D CA  1 
ATOM   11149 C C   . SER D 1 365 ? 36.524  -52.896 146.126 1.00 43.44  ? 384 SER D C   1 
ATOM   11150 O O   . SER D 1 365 ? 36.653  -52.189 147.124 1.00 43.81  ? 384 SER D O   1 
ATOM   11151 C CB  . SER D 1 365 ? 35.848  -55.073 147.108 1.00 46.03  ? 384 SER D CB  1 
ATOM   11152 O OG  . SER D 1 365 ? 36.965  -55.812 146.635 1.00 44.66  ? 384 SER D OG  1 
ATOM   11153 N N   . LYS D 1 366 ? 37.294  -52.775 145.059 1.00 46.80  ? 385 LYS D N   1 
ATOM   11154 C CA  . LYS D 1 366 ? 38.450  -51.916 144.991 1.00 46.15  ? 385 LYS D CA  1 
ATOM   11155 C C   . LYS D 1 366 ? 39.523  -52.309 145.987 1.00 47.36  ? 385 LYS D C   1 
ATOM   11156 O O   . LYS D 1 366 ? 40.339  -51.456 146.361 1.00 47.58  ? 385 LYS D O   1 
ATOM   11157 C CB  . LYS D 1 366 ? 38.103  -50.448 145.260 1.00 46.98  ? 385 LYS D CB  1 
ATOM   11158 C CG  . LYS D 1 366 ? 36.852  -49.928 144.630 1.00 48.21  ? 385 LYS D CG  1 
ATOM   11159 C CD  . LYS D 1 366 ? 36.954  -49.751 143.128 1.00 46.49  ? 385 LYS D CD  1 
ATOM   11160 C CE  . LYS D 1 366 ? 35.741  -48.899 142.606 1.00 47.26  ? 385 LYS D CE  1 
ATOM   11161 N NZ  . LYS D 1 366 ? 34.556  -49.852 142.395 1.00 48.09  ? 385 LYS D NZ  1 
ATOM   11162 N N   . GLU D 1 367 ? 39.504  -53.532 146.524 1.00 42.95  ? 386 GLU D N   1 
ATOM   11163 C CA  . GLU D 1 367 ? 40.593  -53.931 147.414 1.00 44.02  ? 386 GLU D CA  1 
ATOM   11164 C C   . GLU D 1 367 ? 41.780  -54.340 146.543 1.00 42.32  ? 386 GLU D C   1 
ATOM   11165 O O   . GLU D 1 367 ? 41.625  -54.659 145.366 1.00 41.27  ? 386 GLU D O   1 
ATOM   11166 C CB  . GLU D 1 367 ? 40.124  -55.024 148.357 1.00 46.34  ? 386 GLU D CB  1 
ATOM   11167 N N   . ALA D 1 368 ? 42.986  -54.276 147.103 1.00 40.08  ? 387 ALA D N   1 
ATOM   11168 C CA  . ALA D 1 368 ? 44.163  -54.563 146.295 1.00 39.22  ? 387 ALA D CA  1 
ATOM   11169 C C   . ALA D 1 368 ? 45.305  -54.963 147.203 1.00 40.09  ? 387 ALA D C   1 
ATOM   11170 O O   . ALA D 1 368 ? 45.309  -54.638 148.386 1.00 41.49  ? 387 ALA D O   1 
ATOM   11171 C CB  . ALA D 1 368 ? 44.548  -53.365 145.437 1.00 38.85  ? 387 ALA D CB  1 
ATOM   11172 N N   . GLU D 1 369 ? 46.267  -55.708 146.642 1.00 40.31  ? 388 GLU D N   1 
ATOM   11173 C CA  . GLU D 1 369 ? 47.417  -56.166 147.412 1.00 41.68  ? 388 GLU D CA  1 
ATOM   11174 C C   . GLU D 1 369 ? 48.623  -56.226 146.489 1.00 40.56  ? 388 GLU D C   1 
ATOM   11175 O O   . GLU D 1 369 ? 48.504  -56.619 145.334 1.00 39.52  ? 388 GLU D O   1 
ATOM   11176 C CB  . GLU D 1 369 ? 47.191  -57.535 148.064 1.00 43.80  ? 388 GLU D CB  1 
ATOM   11177 N N   . ILE D 1 370 ? 49.778  -55.814 147.002 1.00 44.05  ? 389 ILE D N   1 
ATOM   11178 C CA  . ILE D 1 370 ? 51.054  -56.002 146.325 1.00 44.38  ? 389 ILE D CA  1 
ATOM   11179 C C   . ILE D 1 370 ? 52.032  -56.499 147.373 1.00 46.07  ? 389 ILE D C   1 
ATOM   11180 O O   . ILE D 1 370 ? 52.281  -55.801 148.358 1.00 47.54  ? 389 ILE D O   1 
ATOM   11181 C CB  . ILE D 1 370 ? 51.575  -54.711 145.693 1.00 44.58  ? 389 ILE D CB  1 
ATOM   11182 C CG1 . ILE D 1 370 ? 50.570  -54.144 144.681 1.00 43.39  ? 389 ILE D CG1 1 
ATOM   11183 C CG2 . ILE D 1 370 ? 52.875  -54.967 144.961 1.00 45.45  ? 389 ILE D CG2 1 
ATOM   11184 C CD1 . ILE D 1 370 ? 50.919  -52.779 144.195 1.00 43.04  ? 389 ILE D CD1 1 
ATOM   11185 N N   . ARG D 1 371 ? 52.551  -57.722 147.207 1.00 46.84  ? 390 ARG D N   1 
ATOM   11186 C CA  . ARG D 1 371 ? 53.617  -58.239 148.071 1.00 48.73  ? 390 ARG D CA  1 
ATOM   11187 C C   . ARG D 1 371 ? 54.914  -58.161 147.262 1.00 48.81  ? 390 ARG D C   1 
ATOM   11188 O O   . ARG D 1 371 ? 55.050  -58.826 146.228 1.00 48.65  ? 390 ARG D O   1 
ATOM   11189 C CB  . ARG D 1 371 ? 53.318  -59.656 148.551 1.00 50.07  ? 390 ARG D CB  1 
ATOM   11190 N N   . TRP D 1 372 ? 55.845  -57.307 147.699 1.00 50.60  ? 391 TRP D N   1 
ATOM   11191 C CA  . TRP D 1 372 ? 57.171  -57.210 147.080 1.00 51.68  ? 391 TRP D CA  1 
ATOM   11192 C C   . TRP D 1 372 ? 58.096  -58.246 147.717 1.00 53.30  ? 391 TRP D C   1 
ATOM   11193 O O   . TRP D 1 372 ? 57.983  -58.532 148.910 1.00 54.13  ? 391 TRP D O   1 
ATOM   11194 C CB  . TRP D 1 372 ? 57.737  -55.787 147.235 1.00 52.14  ? 391 TRP D CB  1 
ATOM   11195 C CG  . TRP D 1 372 ? 56.805  -54.666 146.707 1.00 50.88  ? 391 TRP D CG  1 
ATOM   11196 C CD1 . TRP D 1 372 ? 55.837  -53.993 147.401 1.00 50.43  ? 391 TRP D CD1 1 
ATOM   11197 C CD2 . TRP D 1 372 ? 56.796  -54.118 145.388 1.00 49.94  ? 391 TRP D CD2 1 
ATOM   11198 N NE1 . TRP D 1 372 ? 55.218  -53.085 146.593 1.00 49.54  ? 391 TRP D NE1 1 
ATOM   11199 C CE2 . TRP D 1 372 ? 55.792  -53.134 145.354 1.00 49.05  ? 391 TRP D CE2 1 
ATOM   11200 C CE3 . TRP D 1 372 ? 57.529  -54.382 144.230 1.00 49.97  ? 391 TRP D CE3 1 
ATOM   11201 C CZ2 . TRP D 1 372 ? 55.499  -52.401 144.205 1.00 48.21  ? 391 TRP D CZ2 1 
ATOM   11202 C CZ3 . TRP D 1 372 ? 57.243  -53.675 143.089 1.00 49.29  ? 391 TRP D CZ3 1 
ATOM   11203 C CH2 . TRP D 1 372 ? 56.233  -52.680 143.080 1.00 48.30  ? 391 TRP D CH2 1 
ATOM   11204 N N   . ARG D 1 373 ? 58.986  -58.829 146.912 1.00 52.52  ? 392 ARG D N   1 
ATOM   11205 C CA  . ARG D 1 373 ? 59.719  -60.051 147.326 1.00 54.37  ? 392 ARG D CA  1 
ATOM   11206 C C   . ARG D 1 373 ? 61.163  -60.028 146.800 1.00 55.67  ? 392 ARG D C   1 
ATOM   11207 O O   . ARG D 1 373 ? 61.615  -58.992 146.272 1.00 55.90  ? 392 ARG D O   1 
ATOM   11208 C CB  . ARG D 1 373 ? 59.006  -61.326 146.833 1.00 54.51  ? 392 ARG D CB  1 
ATOM   11209 N N   . SER E 1 19  ? 49.509  -10.927 116.175 1.00 65.80  ? 38  SER E N   1 
ATOM   11210 C CA  . SER E 1 19  ? 48.147  -10.561 115.802 1.00 64.34  ? 38  SER E CA  1 
ATOM   11211 C C   . SER E 1 19  ? 48.067  -9.071  115.522 1.00 60.61  ? 38  SER E C   1 
ATOM   11212 O O   . SER E 1 19  ? 47.028  -8.565  115.107 1.00 59.65  ? 38  SER E O   1 
ATOM   11213 C CB  . SER E 1 19  ? 47.149  -10.931 116.900 1.00 68.36  ? 38  SER E CB  1 
ATOM   11214 O OG  . SER E 1 19  ? 47.753  -10.873 118.181 1.00 71.00  ? 38  SER E OG  1 
ATOM   11215 N N   . HIS E 1 20  ? 49.164  -8.360  115.774 1.00 60.30  ? 39  HIS E N   1 
ATOM   11216 C CA  . HIS E 1 20  ? 49.240  -6.935  115.486 1.00 57.69  ? 39  HIS E CA  1 
ATOM   11217 C C   . HIS E 1 20  ? 50.090  -6.658  114.261 1.00 54.02  ? 39  HIS E C   1 
ATOM   11218 O O   . HIS E 1 20  ? 50.421  -5.506  113.985 1.00 52.90  ? 39  HIS E O   1 
ATOM   11219 C CB  . HIS E 1 20  ? 49.781  -6.152  116.703 1.00 59.60  ? 39  HIS E CB  1 
ATOM   11220 C CG  . HIS E 1 20  ? 51.161  -6.551  117.152 1.00 60.37  ? 39  HIS E CG  1 
ATOM   11221 N ND1 . HIS E 1 20  ? 51.442  -7.781  117.713 1.00 62.74  ? 39  HIS E ND1 1 
ATOM   11222 C CD2 . HIS E 1 20  ? 52.325  -5.850  117.175 1.00 60.05  ? 39  HIS E CD2 1 
ATOM   11223 C CE1 . HIS E 1 20  ? 52.729  -7.836  118.018 1.00 63.12  ? 39  HIS E CE1 1 
ATOM   11224 N NE2 . HIS E 1 20  ? 53.286  -6.677  117.705 1.00 61.12  ? 39  HIS E NE2 1 
ATOM   11225 N N   . TYR E 1 21  ? 50.464  -7.675  113.531 1.00 50.35  ? 40  TYR E N   1 
ATOM   11226 C CA  . TYR E 1 21  ? 51.283  -7.435  112.361 1.00 48.09  ? 40  TYR E CA  1 
ATOM   11227 C C   . TYR E 1 21  ? 50.418  -6.898  111.218 1.00 46.59  ? 40  TYR E C   1 
ATOM   11228 O O   . TYR E 1 21  ? 49.188  -6.981  111.256 1.00 47.44  ? 40  TYR E O   1 
ATOM   11229 C CB  . TYR E 1 21  ? 51.987  -8.720  111.950 1.00 48.23  ? 40  TYR E CB  1 
ATOM   11230 C CG  . TYR E 1 21  ? 53.157  -9.164  112.806 1.00 49.40  ? 40  TYR E CG  1 
ATOM   11231 C CD1 . TYR E 1 21  ? 53.481  -8.516  113.996 1.00 50.87  ? 40  TYR E CD1 1 
ATOM   11232 C CD2 . TYR E 1 21  ? 53.935  -10.252 112.417 1.00 49.67  ? 40  TYR E CD2 1 
ATOM   11233 C CE1 . TYR E 1 21  ? 54.552  -8.942  114.774 1.00 52.36  ? 40  TYR E CE1 1 
ATOM   11234 C CE2 . TYR E 1 21  ? 54.994  -10.683 113.180 1.00 51.46  ? 40  TYR E CE2 1 
ATOM   11235 C CZ  . TYR E 1 21  ? 55.304  -10.033 114.364 1.00 52.51  ? 40  TYR E CZ  1 
ATOM   11236 O OH  . TYR E 1 21  ? 56.381  -10.488 115.123 1.00 54.88  ? 40  TYR E OH  1 
ATOM   11237 N N   . PRO E 1 22  ? 51.041  -6.298  110.208 1.00 44.97  ? 41  PRO E N   1 
ATOM   11238 C CA  . PRO E 1 22  ? 50.301  -5.951  108.990 1.00 43.80  ? 41  PRO E CA  1 
ATOM   11239 C C   . PRO E 1 22  ? 49.689  -7.179  108.347 1.00 43.89  ? 41  PRO E C   1 
ATOM   11240 O O   . PRO E 1 22  ? 50.307  -8.238  108.321 1.00 44.26  ? 41  PRO E O   1 
ATOM   11241 C CB  . PRO E 1 22  ? 51.381  -5.344  108.086 1.00 42.33  ? 41  PRO E CB  1 
ATOM   11242 C CG  . PRO E 1 22  ? 52.506  -5.044  108.971 1.00 43.11  ? 41  PRO E CG  1 
ATOM   11243 C CD  . PRO E 1 22  ? 52.476  -5.994  110.076 1.00 44.45  ? 41  PRO E CD  1 
ATOM   11244 N N   . GLU E 1 23  ? 48.504  -7.030  107.781 1.00 45.60  ? 42  GLU E N   1 
ATOM   11245 C CA  . GLU E 1 23  ? 47.912  -8.176  107.107 1.00 46.07  ? 42  GLU E CA  1 
ATOM   11246 C C   . GLU E 1 23  ? 48.782  -8.595  105.920 1.00 44.95  ? 42  GLU E C   1 
ATOM   11247 O O   . GLU E 1 23  ? 49.061  -7.795  105.021 1.00 44.14  ? 42  GLU E O   1 
ATOM   11248 C CB  . GLU E 1 23  ? 46.495  -7.899  106.627 1.00 47.19  ? 42  GLU E CB  1 
ATOM   11249 C CG  . GLU E 1 23  ? 45.869  -9.142  105.988 1.00 49.18  ? 42  GLU E CG  1 
ATOM   11250 C CD  . GLU E 1 23  ? 44.451  -8.900  105.517 1.00 50.43  ? 42  GLU E CD  1 
ATOM   11251 O OE1 . GLU E 1 23  ? 43.532  -8.727  106.375 1.00 51.64  ? 42  GLU E OE1 1 
ATOM   11252 O OE2 . GLU E 1 23  ? 44.254  -8.866  104.281 1.00 51.28  ? 42  GLU E OE2 1 
ATOM   11253 N N   . PHE E 1 24  ? 49.195  -9.858  105.912 1.00 42.34  ? 43  PHE E N   1 
ATOM   11254 C CA  . PHE E 1 24  ? 50.136  -10.373 104.932 1.00 41.26  ? 43  PHE E CA  1 
ATOM   11255 C C   . PHE E 1 24  ? 49.426  -11.310 103.962 1.00 41.81  ? 43  PHE E C   1 
ATOM   11256 O O   . PHE E 1 24  ? 48.496  -12.020 104.339 1.00 43.68  ? 43  PHE E O   1 
ATOM   11257 C CB  . PHE E 1 24  ? 51.279  -11.096 105.622 1.00 41.85  ? 43  PHE E CB  1 
ATOM   11258 C CG  . PHE E 1 24  ? 52.255  -11.691 104.684 1.00 41.10  ? 43  PHE E CG  1 
ATOM   11259 C CD1 . PHE E 1 24  ? 53.350  -10.966 104.278 1.00 39.69  ? 43  PHE E CD1 1 
ATOM   11260 C CD2 . PHE E 1 24  ? 52.079  -12.980 104.188 1.00 42.11  ? 43  PHE E CD2 1 
ATOM   11261 C CE1 . PHE E 1 24  ? 54.272  -11.506 103.397 1.00 39.24  ? 43  PHE E CE1 1 
ATOM   11262 C CE2 . PHE E 1 24  ? 52.999  -13.543 103.316 1.00 41.70  ? 43  PHE E CE2 1 
ATOM   11263 C CZ  . PHE E 1 24  ? 54.094  -12.815 102.919 1.00 40.33  ? 43  PHE E CZ  1 
ATOM   11264 N N   . SER E 1 25  ? 49.866  -11.276 102.709 1.00 40.98  ? 44  SER E N   1 
ATOM   11265 C CA  . SER E 1 25  ? 49.332  -12.150 101.696 1.00 41.90  ? 44  SER E CA  1 
ATOM   11266 C C   . SER E 1 25  ? 50.403  -12.512 100.679 1.00 41.03  ? 44  SER E C   1 
ATOM   11267 O O   . SER E 1 25  ? 51.251  -11.696 100.324 1.00 39.80  ? 44  SER E O   1 
ATOM   11268 C CB  . SER E 1 25  ? 48.174  -11.543 100.906 1.00 42.66  ? 44  SER E CB  1 
ATOM   11269 O OG  . SER E 1 25  ? 47.815  -12.458 99.864  1.00 43.67  ? 44  SER E OG  1 
ATOM   11270 N N   . TRP E 1 26  ? 50.302  -13.728 100.162 1.00 41.00  ? 45  TRP E N   1 
ATOM   11271 C CA  . TRP E 1 26  ? 51.178  -14.193 99.099  1.00 40.77  ? 45  TRP E CA  1 
ATOM   11272 C C   . TRP E 1 26  ? 50.592  -13.964 97.709  1.00 40.59  ? 45  TRP E C   1 
ATOM   11273 O O   . TRP E 1 26  ? 51.305  -14.178 96.714  1.00 41.05  ? 45  TRP E O   1 
ATOM   11274 C CB  . TRP E 1 26  ? 51.439  -15.682 99.268  1.00 42.51  ? 45  TRP E CB  1 
ATOM   11275 C CG  . TRP E 1 26  ? 52.455  -16.091 100.297 1.00 42.91  ? 45  TRP E CG  1 
ATOM   11276 C CD1 . TRP E 1 26  ? 52.231  -16.904 101.367 1.00 44.89  ? 45  TRP E CD1 1 
ATOM   11277 C CD2 . TRP E 1 26  ? 53.852  -15.756 100.329 1.00 41.99  ? 45  TRP E CD2 1 
ATOM   11278 N NE1 . TRP E 1 26  ? 53.393  -17.094 102.062 1.00 45.37  ? 45  TRP E NE1 1 
ATOM   11279 C CE2 . TRP E 1 26  ? 54.406  -16.403 101.455 1.00 43.73  ? 45  TRP E CE2 1 
ATOM   11280 C CE3 . TRP E 1 26  ? 54.678  -14.952 99.533  1.00 40.66  ? 45  TRP E CE3 1 
ATOM   11281 C CZ2 . TRP E 1 26  ? 55.749  -16.296 101.802 1.00 43.98  ? 45  TRP E CZ2 1 
ATOM   11282 C CZ3 . TRP E 1 26  ? 56.029  -14.856 99.866  1.00 40.79  ? 45  TRP E CZ3 1 
ATOM   11283 C CH2 . TRP E 1 26  ? 56.550  -15.539 100.999 1.00 42.59  ? 45  TRP E CH2 1 
ATOM   11284 N N   . ASP E 1 27  ? 49.315  -13.568 97.616  1.00 39.94  ? 46  ASP E N   1 
ATOM   11285 C CA  . ASP E 1 27  ? 48.687  -13.427 96.313  1.00 40.49  ? 46  ASP E CA  1 
ATOM   11286 C C   . ASP E 1 27  ? 49.641  -12.820 95.285  1.00 39.67  ? 46  ASP E C   1 
ATOM   11287 O O   . ASP E 1 27  ? 49.778  -13.331 94.171  1.00 40.52  ? 46  ASP E O   1 
ATOM   11288 C CB  . ASP E 1 27  ? 47.427  -12.597 96.458  1.00 40.75  ? 46  ASP E CB  1 
ATOM   11289 C CG  . ASP E 1 27  ? 46.298  -13.346 97.192  1.00 42.50  ? 46  ASP E CG  1 
ATOM   11290 O OD1 . ASP E 1 27  ? 46.353  -14.585 97.354  1.00 44.60  ? 46  ASP E OD1 1 
ATOM   11291 O OD2 . ASP E 1 27  ? 45.300  -12.698 97.582  1.00 43.07  ? 46  ASP E OD2 1 
ATOM   11292 N N   . THR E 1 28  ? 50.335  -11.729 95.650  1.00 39.19  ? 47  THR E N   1 
ATOM   11293 C CA  . THR E 1 28  ? 51.320  -11.101 94.784  1.00 38.26  ? 47  THR E CA  1 
ATOM   11294 C C   . THR E 1 28  ? 52.529  -10.755 95.635  1.00 36.77  ? 47  THR E C   1 
ATOM   11295 O O   . THR E 1 28  ? 52.539  -10.965 96.849  1.00 36.69  ? 47  THR E O   1 
ATOM   11296 C CB  . THR E 1 28  ? 50.763  -9.850  94.098  1.00 38.25  ? 47  THR E CB  1 
ATOM   11297 O OG1 . THR E 1 28  ? 50.227  -8.959  95.083  1.00 37.88  ? 47  THR E OG1 1 
ATOM   11298 C CG2 . THR E 1 28  ? 49.662  -10.223 93.119  1.00 40.05  ? 47  THR E CG2 1 
ATOM   11299 N N   . VAL E 1 29  ? 53.555  -10.207 95.012  1.00 35.30  ? 48  VAL E N   1 
ATOM   11300 C CA  . VAL E 1 29  ? 54.741  -9.846  95.783  1.00 34.09  ? 48  VAL E CA  1 
ATOM   11301 C C   . VAL E 1 29  ? 54.414  -8.922  96.960  1.00 33.43  ? 48  VAL E C   1 
ATOM   11302 O O   . VAL E 1 29  ? 53.863  -7.832  96.744  1.00 33.46  ? 48  VAL E O   1 
ATOM   11303 C CB  . VAL E 1 29  ? 55.788  -9.189  94.874  1.00 33.77  ? 48  VAL E CB  1 
ATOM   11304 C CG1 . VAL E 1 29  ? 56.888  -8.657  95.715  1.00 33.11  ? 48  VAL E CG1 1 
ATOM   11305 C CG2 . VAL E 1 29  ? 56.316  -10.148 93.884  1.00 34.73  ? 48  VAL E CG2 1 
ATOM   11306 N N   . PRO E 1 30  ? 54.748  -9.300  98.205  1.00 34.67  ? 49  PRO E N   1 
ATOM   11307 C CA  . PRO E 1 30  ? 54.464  -8.421  99.358  1.00 34.46  ? 49  PRO E CA  1 
ATOM   11308 C C   . PRO E 1 30  ? 55.346  -7.186  99.368  1.00 33.90  ? 49  PRO E C   1 
ATOM   11309 O O   . PRO E 1 30  ? 56.574  -7.278  99.446  1.00 33.71  ? 49  PRO E O   1 
ATOM   11310 C CB  . PRO E 1 30  ? 54.734  -9.306  100.585 1.00 35.74  ? 49  PRO E CB  1 
ATOM   11311 C CG  . PRO E 1 30  ? 55.434  -10.444 100.120 1.00 36.85  ? 49  PRO E CG  1 
ATOM   11312 C CD  . PRO E 1 30  ? 55.210  -10.634 98.643  1.00 35.91  ? 49  PRO E CD  1 
ATOM   11313 N N   . ILE E 1 31  ? 54.693  -6.029  99.322  1.00 32.98  ? 50  ILE E N   1 
ATOM   11314 C CA  . ILE E 1 31  ? 55.326  -4.732  99.112  1.00 33.01  ? 50  ILE E CA  1 
ATOM   11315 C C   . ILE E 1 31  ? 55.106  -3.884  100.357 1.00 33.17  ? 50  ILE E C   1 
ATOM   11316 O O   . ILE E 1 31  ? 54.048  -3.959  100.986 1.00 34.13  ? 50  ILE E O   1 
ATOM   11317 C CB  . ILE E 1 31  ? 54.734  -4.004  97.885  1.00 33.91  ? 50  ILE E CB  1 
ATOM   11318 C CG1 . ILE E 1 31  ? 55.108  -4.696  96.574  1.00 34.13  ? 50  ILE E CG1 1 
ATOM   11319 C CG2 . ILE E 1 31  ? 55.142  -2.507  97.905  1.00 34.52  ? 50  ILE E CG2 1 
ATOM   11320 C CD1 . ILE E 1 31  ? 56.559  -4.631  96.236  1.00 33.58  ? 50  ILE E CD1 1 
ATOM   11321 N N   . ALA E 1 32  ? 56.077  -3.068  100.697 1.00 33.66  ? 51  ALA E N   1 
ATOM   11322 C CA  . ALA E 1 32  ? 55.892  -2.020  101.692 1.00 34.49  ? 51  ALA E CA  1 
ATOM   11323 C C   . ALA E 1 32  ? 56.376  -0.691  101.115 1.00 34.72  ? 51  ALA E C   1 
ATOM   11324 O O   . ALA E 1 32  ? 56.972  -0.637  100.030 1.00 34.17  ? 51  ALA E O   1 
ATOM   11325 C CB  . ALA E 1 32  ? 56.630  -2.359  102.988 1.00 34.83  ? 51  ALA E CB  1 
ATOM   11326 N N   . PHE E 1 33  ? 56.110  0.392   101.850 1.00 35.95  ? 52  PHE E N   1 
ATOM   11327 C CA  . PHE E 1 33  ? 56.542  1.720   101.423 1.00 36.49  ? 52  PHE E CA  1 
ATOM   11328 C C   . PHE E 1 33  ? 57.307  2.418   102.542 1.00 37.44  ? 52  PHE E C   1 
ATOM   11329 O O   . PHE E 1 33  ? 56.939  2.348   103.717 1.00 38.33  ? 52  PHE E O   1 
ATOM   11330 C CB  . PHE E 1 33  ? 55.366  2.621   100.995 1.00 38.22  ? 52  PHE E CB  1 
ATOM   11331 C CG  . PHE E 1 33  ? 54.661  2.167   99.735  1.00 37.99  ? 52  PHE E CG  1 
ATOM   11332 C CD1 . PHE E 1 33  ? 55.228  2.361   98.493  1.00 38.03  ? 52  PHE E CD1 1 
ATOM   11333 C CD2 . PHE E 1 33  ? 53.423  1.552   99.795  1.00 38.11  ? 52  PHE E CD2 1 
ATOM   11334 C CE1 . PHE E 1 33  ? 54.571  1.973   97.347  1.00 38.53  ? 52  PHE E CE1 1 
ATOM   11335 C CE2 . PHE E 1 33  ? 52.777  1.147   98.637  1.00 38.37  ? 52  PHE E CE2 1 
ATOM   11336 C CZ  . PHE E 1 33  ? 53.351  1.369   97.427  1.00 38.71  ? 52  PHE E CZ  1 
ATOM   11337 N N   . HIS E 1 34  ? 58.374  3.104   102.170 1.00 40.18  ? 53  HIS E N   1 
ATOM   11338 C CA  . HIS E 1 34  ? 59.171  3.853   103.137 1.00 41.40  ? 53  HIS E CA  1 
ATOM   11339 C C   . HIS E 1 34  ? 59.664  5.108   102.422 1.00 42.42  ? 53  HIS E C   1 
ATOM   11340 O O   . HIS E 1 34  ? 60.650  5.054   101.687 1.00 42.07  ? 53  HIS E O   1 
ATOM   11341 C CB  . HIS E 1 34  ? 60.305  2.987   103.653 1.00 40.79  ? 53  HIS E CB  1 
ATOM   11342 C CG  . HIS E 1 34  ? 61.038  3.573   104.817 1.00 42.39  ? 53  HIS E CG  1 
ATOM   11343 N ND1 . HIS E 1 34  ? 61.126  4.932   105.043 1.00 44.73  ? 53  HIS E ND1 1 
ATOM   11344 C CD2 . HIS E 1 34  ? 61.734  2.979   105.815 1.00 42.92  ? 53  HIS E CD2 1 
ATOM   11345 C CE1 . HIS E 1 34  ? 61.834  5.146   106.137 1.00 45.49  ? 53  HIS E CE1 1 
ATOM   11346 N NE2 . HIS E 1 34  ? 62.218  3.978   106.622 1.00 44.39  ? 53  HIS E NE2 1 
ATOM   11347 N N   . PHE E 1 35  ? 58.956  6.216   102.612 1.00 40.88  ? 54  PHE E N   1 
ATOM   11348 C CA  . PHE E 1 35  ? 59.292  7.455   101.921 1.00 42.82  ? 54  PHE E CA  1 
ATOM   11349 C C   . PHE E 1 35  ? 58.638  8.629   102.640 1.00 45.42  ? 54  PHE E C   1 
ATOM   11350 O O   . PHE E 1 35  ? 57.733  8.457   103.463 1.00 45.56  ? 54  PHE E O   1 
ATOM   11351 C CB  . PHE E 1 35  ? 58.841  7.427   100.438 1.00 42.62  ? 54  PHE E CB  1 
ATOM   11352 C CG  . PHE E 1 35  ? 57.334  7.462   100.252 1.00 43.38  ? 54  PHE E CG  1 
ATOM   11353 C CD1 . PHE E 1 35  ? 56.637  8.647   100.280 1.00 46.86  ? 54  PHE E CD1 1 
ATOM   11354 C CD2 . PHE E 1 35  ? 56.626  6.307   100.066 1.00 41.54  ? 54  PHE E CD2 1 
ATOM   11355 C CE1 . PHE E 1 35  ? 55.249  8.682   100.130 1.00 47.50  ? 54  PHE E CE1 1 
ATOM   11356 C CE2 . PHE E 1 35  ? 55.252  6.333   99.910  1.00 42.34  ? 54  PHE E CE2 1 
ATOM   11357 C CZ  . PHE E 1 35  ? 54.564  7.527   99.946  1.00 45.23  ? 54  PHE E CZ  1 
ATOM   11358 N N   . GLY E 1 36  ? 59.104  9.829   102.290 1.00 44.99  ? 55  GLY E N   1 
ATOM   11359 C CA  . GLY E 1 36  ? 58.454  11.053  102.708 1.00 48.09  ? 55  GLY E CA  1 
ATOM   11360 C C   . GLY E 1 36  ? 58.222  11.993  101.541 1.00 50.14  ? 55  GLY E C   1 
ATOM   11361 O O   . GLY E 1 36  ? 59.001  12.050  100.595 1.00 50.08  ? 55  GLY E O   1 
ATOM   11362 N N   . LYS E 1 37  ? 57.121  12.738  101.621 1.00 51.52  ? 56  LYS E N   1 
ATOM   11363 C CA  . LYS E 1 37  ? 56.774  13.758  100.627 1.00 52.51  ? 56  LYS E CA  1 
ATOM   11364 C C   . LYS E 1 37  ? 56.753  15.126  101.310 1.00 54.96  ? 56  LYS E C   1 
ATOM   11365 O O   . LYS E 1 37  ? 55.720  15.557  101.817 1.00 55.98  ? 56  LYS E O   1 
ATOM   11366 C CB  . LYS E 1 37  ? 55.426  13.450  99.975  1.00 51.90  ? 56  LYS E CB  1 
ATOM   11367 C CG  . LYS E 1 37  ? 54.964  14.535  99.015  1.00 53.45  ? 56  LYS E CG  1 
ATOM   11368 C CD  . LYS E 1 37  ? 53.552  14.284  98.519  1.00 53.47  ? 56  LYS E CD  1 
ATOM   11369 C CE  . LYS E 1 37  ? 53.052  15.418  97.634  1.00 55.31  ? 56  LYS E CE  1 
ATOM   11370 N NZ  . LYS E 1 37  ? 51.710  15.073  97.097  1.00 55.45  ? 56  LYS E NZ  1 
ATOM   11371 N N   . SER E 1 38  ? 57.894  15.810  101.302 1.00 55.44  ? 57  SER E N   1 
ATOM   11372 C CA  . SER E 1 38  ? 58.063  17.006  102.128 1.00 58.61  ? 57  SER E CA  1 
ATOM   11373 C C   . SER E 1 38  ? 57.162  18.152  101.684 1.00 59.87  ? 57  SER E C   1 
ATOM   11374 O O   . SER E 1 38  ? 56.831  19.024  102.495 1.00 61.72  ? 57  SER E O   1 
ATOM   11375 C CB  . SER E 1 38  ? 59.521  17.448  102.084 1.00 60.27  ? 57  SER E CB  1 
ATOM   11376 O OG  . SER E 1 38  ? 59.947  17.583  100.740 1.00 59.87  ? 57  SER E OG  1 
ATOM   11377 N N   . GLN E 1 39  ? 56.702  18.114  100.443 1.00 61.29  ? 58  GLN E N   1 
ATOM   11378 C CA  . GLN E 1 39  ? 56.021  19.208  99.775  1.00 63.69  ? 58  GLN E CA  1 
ATOM   11379 C C   . GLN E 1 39  ? 54.516  19.201  99.972  1.00 63.73  ? 58  GLN E C   1 
ATOM   11380 O O   . GLN E 1 39  ? 53.852  20.206  99.643  1.00 66.17  ? 58  GLN E O   1 
ATOM   11381 C CB  . GLN E 1 39  ? 56.439  19.136  98.309  1.00 64.30  ? 58  GLN E CB  1 
ATOM   11382 C CG  . GLN E 1 39  ? 55.444  19.465  97.251  1.00 63.06  ? 58  GLN E CG  1 
ATOM   11383 C CD  . GLN E 1 39  ? 55.957  18.994  95.870  1.00 61.34  ? 58  GLN E CD  1 
ATOM   11384 O OE1 . GLN E 1 39  ? 57.186  18.819  95.664  1.00 60.74  ? 58  GLN E OE1 1 
ATOM   11385 N NE2 . GLN E 1 39  ? 55.016  18.748  94.936  1.00 60.39  ? 58  GLN E NE2 1 
ATOM   11386 N N   . GLY E 1 40  ? 53.979  18.149  100.555 1.00 60.07  ? 59  GLY E N   1 
ATOM   11387 C CA  . GLY E 1 40  ? 52.595  18.151  100.978 1.00 60.25  ? 59  GLY E CA  1 
ATOM   11388 C C   . GLY E 1 40  ? 52.094  16.739  101.191 1.00 57.46  ? 59  GLY E C   1 
ATOM   11389 O O   . GLY E 1 40  ? 52.802  15.758  100.967 1.00 55.86  ? 59  GLY E O   1 
ATOM   11390 N N   . LEU E 1 41  ? 50.846  16.657  101.637 1.00 59.00  ? 60  LEU E N   1 
ATOM   11391 C CA  . LEU E 1 41  ? 50.216  15.359  101.783 1.00 56.91  ? 60  LEU E CA  1 
ATOM   11392 C C   . LEU E 1 41  ? 50.050  14.695  100.413 1.00 55.74  ? 60  LEU E C   1 
ATOM   11393 O O   . LEU E 1 41  ? 50.059  15.349  99.361  1.00 57.04  ? 60  LEU E O   1 
ATOM   11394 C CB  . LEU E 1 41  ? 48.858  15.499  102.461 1.00 57.83  ? 60  LEU E CB  1 
ATOM   11395 C CG  . LEU E 1 41  ? 48.877  15.784  103.957 1.00 59.13  ? 60  LEU E CG  1 
ATOM   11396 C CD1 . LEU E 1 41  ? 47.504  16.194  104.413 1.00 60.36  ? 60  LEU E CD1 1 
ATOM   11397 C CD2 . LEU E 1 41  ? 49.331  14.550  104.696 1.00 57.12  ? 60  LEU E CD2 1 
ATOM   11398 N N   . LEU E 1 42  ? 49.877  13.385  100.428 1.00 54.53  ? 61  LEU E N   1 
ATOM   11399 C CA  . LEU E 1 42  ? 49.672  12.684  99.175  1.00 53.65  ? 61  LEU E CA  1 
ATOM   11400 C C   . LEU E 1 42  ? 48.398  13.185  98.505  1.00 55.27  ? 61  LEU E C   1 
ATOM   11401 O O   . LEU E 1 42  ? 47.375  13.411  99.161  1.00 56.14  ? 61  LEU E O   1 
ATOM   11402 C CB  . LEU E 1 42  ? 49.582  11.164  99.402  1.00 51.34  ? 61  LEU E CB  1 
ATOM   11403 C CG  . LEU E 1 42  ? 50.788  10.473  100.031 1.00 50.14  ? 61  LEU E CG  1 
ATOM   11404 C CD1 . LEU E 1 42  ? 50.513  8.989   100.192 1.00 48.03  ? 61  LEU E CD1 1 
ATOM   11405 C CD2 . LEU E 1 42  ? 52.028  10.715  99.203  1.00 50.76  ? 61  LEU E CD2 1 
ATOM   11406 N N   . THR E 1 43  ? 48.456  13.342  97.186  1.00 52.35  ? 62  THR E N   1 
ATOM   11407 C CA  . THR E 1 43  ? 47.257  13.636  96.429  1.00 53.70  ? 62  THR E CA  1 
ATOM   11408 C C   . THR E 1 43  ? 46.280  12.464  96.489  1.00 52.60  ? 62  THR E C   1 
ATOM   11409 O O   . THR E 1 43  ? 46.609  11.355  96.923  1.00 50.61  ? 62  THR E O   1 
ATOM   11410 C CB  . THR E 1 43  ? 47.613  13.939  94.979  1.00 54.99  ? 62  THR E CB  1 
ATOM   11411 O OG1 . THR E 1 43  ? 47.869  12.722  94.279  1.00 53.39  ? 62  THR E OG1 1 
ATOM   11412 C CG2 . THR E 1 43  ? 48.865  14.841  94.901  1.00 56.27  ? 62  THR E CG2 1 
ATOM   11413 N N   . LYS E 1 44  ? 45.045  12.734  96.055  1.00 52.86  ? 63  LYS E N   1 
ATOM   11414 C CA  . LYS E 1 44  ? 44.052  11.670  95.924  1.00 52.84  ? 63  LYS E CA  1 
ATOM   11415 C C   . LYS E 1 44  ? 44.669  10.456  95.226  1.00 50.67  ? 63  LYS E C   1 
ATOM   11416 O O   . LYS E 1 44  ? 44.583  9.327   95.709  1.00 48.92  ? 63  LYS E O   1 
ATOM   11417 C CB  . LYS E 1 44  ? 42.837  12.186  95.148  1.00 56.61  ? 63  LYS E CB  1 
ATOM   11418 N N   . GLU E 1 45  ? 45.313  10.682  94.089  1.00 52.04  ? 64  GLU E N   1 
ATOM   11419 C CA  . GLU E 1 45  ? 45.780  9.581   93.270  1.00 51.05  ? 64  GLU E CA  1 
ATOM   11420 C C   . GLU E 1 45  ? 46.885  8.821   93.982  1.00 47.93  ? 64  GLU E C   1 
ATOM   11421 O O   . GLU E 1 45  ? 46.885  7.578   94.002  1.00 46.47  ? 64  GLU E O   1 
ATOM   11422 C CB  . GLU E 1 45  ? 46.252  10.128  91.928  1.00 53.22  ? 64  GLU E CB  1 
ATOM   11423 C CG  . GLU E 1 45  ? 45.145  10.761  91.100  1.00 56.37  ? 64  GLU E CG  1 
ATOM   11424 C CD  . GLU E 1 45  ? 44.790  12.216  91.534  1.00 59.44  ? 64  GLU E CD  1 
ATOM   11425 O OE1 . GLU E 1 45  ? 45.425  12.748  92.462  1.00 58.97  ? 64  GLU E OE1 1 
ATOM   11426 O OE2 . GLU E 1 45  ? 43.867  12.830  90.944  1.00 63.07  ? 64  GLU E OE2 1 
ATOM   11427 N N   . GLU E 1 46  ? 47.824  9.558   94.581  1.00 50.17  ? 65  GLU E N   1 
ATOM   11428 C CA  . GLU E 1 46  ? 48.933  8.931   95.276  1.00 48.30  ? 65  GLU E CA  1 
ATOM   11429 C C   . GLU E 1 46  ? 48.444  8.148   96.475  1.00 47.19  ? 65  GLU E C   1 
ATOM   11430 O O   . GLU E 1 46  ? 48.912  7.037   96.745  1.00 45.21  ? 65  GLU E O   1 
ATOM   11431 C CB  . GLU E 1 46  ? 49.920  9.999   95.722  1.00 48.99  ? 65  GLU E CB  1 
ATOM   11432 C CG  . GLU E 1 46  ? 50.717  10.568  94.575  1.00 50.32  ? 65  GLU E CG  1 
ATOM   11433 C CD  . GLU E 1 46  ? 51.236  11.972  94.851  1.00 52.12  ? 65  GLU E CD  1 
ATOM   11434 O OE1 . GLU E 1 46  ? 50.814  12.581  95.853  1.00 52.43  ? 65  GLU E OE1 1 
ATOM   11435 O OE2 . GLU E 1 46  ? 52.076  12.453  94.063  1.00 53.30  ? 65  GLU E OE2 1 
ATOM   11436 N N   . ALA E 1 47  ? 47.520  8.727   97.229  1.00 48.84  ? 66  ALA E N   1 
ATOM   11437 C CA  . ALA E 1 47  ? 47.034  8.030   98.403  1.00 47.58  ? 66  ALA E CA  1 
ATOM   11438 C C   . ALA E 1 47  ? 46.387  6.717   97.994  1.00 46.55  ? 66  ALA E C   1 
ATOM   11439 O O   . ALA E 1 47  ? 46.727  5.662   98.527  1.00 44.89  ? 66  ALA E O   1 
ATOM   11440 C CB  . ALA E 1 47  ? 46.060  8.908   99.173  1.00 49.33  ? 66  ALA E CB  1 
ATOM   11441 N N   . GLU E 1 48  ? 45.457  6.761   97.030  1.00 48.98  ? 67  GLU E N   1 
ATOM   11442 C CA  . GLU E 1 48  ? 44.834  5.531   96.543  1.00 48.32  ? 67  GLU E CA  1 
ATOM   11443 C C   . GLU E 1 48  ? 45.891  4.543   96.083  1.00 46.85  ? 67  GLU E C   1 
ATOM   11444 O O   . GLU E 1 48  ? 45.818  3.355   96.397  1.00 45.72  ? 67  GLU E O   1 
ATOM   11445 C CB  . GLU E 1 48  ? 43.862  5.829   95.395  1.00 50.17  ? 67  GLU E CB  1 
ATOM   11446 C CG  . GLU E 1 48  ? 42.411  6.029   95.815  1.00 50.81  ? 67  GLU E CG  1 
ATOM   11447 C CD  . GLU E 1 48  ? 41.540  6.690   94.726  1.00 52.92  ? 67  GLU E CD  1 
ATOM   11448 O OE1 . GLU E 1 48  ? 42.104  7.237   93.734  1.00 54.41  ? 67  GLU E OE1 1 
ATOM   11449 O OE2 . GLU E 1 48  ? 40.278  6.668   94.855  1.00 53.71  ? 67  GLU E OE2 1 
ATOM   11450 N N   . PHE E 1 49  ? 46.901  5.027   95.373  1.00 46.06  ? 68  PHE E N   1 
ATOM   11451 C CA  . PHE E 1 49  ? 47.927  4.135   94.856  1.00 44.34  ? 68  PHE E CA  1 
ATOM   11452 C C   . PHE E 1 49  ? 48.593  3.365   95.983  1.00 42.46  ? 68  PHE E C   1 
ATOM   11453 O O   . PHE E 1 49  ? 48.720  2.137   95.935  1.00 41.60  ? 68  PHE E O   1 
ATOM   11454 C CB  . PHE E 1 49  ? 48.950  4.943   94.077  1.00 45.43  ? 68  PHE E CB  1 
ATOM   11455 C CG  . PHE E 1 49  ? 50.103  4.130   93.587  1.00 44.14  ? 68  PHE E CG  1 
ATOM   11456 C CD1 . PHE E 1 49  ? 51.242  3.973   94.358  1.00 42.59  ? 68  PHE E CD1 1 
ATOM   11457 C CD2 . PHE E 1 49  ? 50.062  3.533   92.337  1.00 44.91  ? 68  PHE E CD2 1 
ATOM   11458 C CE1 . PHE E 1 49  ? 52.328  3.236   93.880  1.00 41.80  ? 68  PHE E CE1 1 
ATOM   11459 C CE2 . PHE E 1 49  ? 51.132  2.801   91.853  1.00 44.35  ? 68  PHE E CE2 1 
ATOM   11460 C CZ  . PHE E 1 49  ? 52.265  2.649   92.622  1.00 42.11  ? 68  PHE E CZ  1 
ATOM   11461 N N   . VAL E 1 50  ? 49.022  4.085   97.013  1.00 42.79  ? 69  VAL E N   1 
ATOM   11462 C CA  . VAL E 1 50  ? 49.696  3.477   98.147  1.00 41.67  ? 69  VAL E CA  1 
ATOM   11463 C C   . VAL E 1 50  ? 48.744  2.566   98.907  1.00 41.10  ? 69  VAL E C   1 
ATOM   11464 O O   . VAL E 1 50  ? 49.053  1.393   99.155  1.00 39.82  ? 69  VAL E O   1 
ATOM   11465 C CB  . VAL E 1 50  ? 50.275  4.596   99.025  1.00 43.39  ? 69  VAL E CB  1 
ATOM   11466 C CG1 . VAL E 1 50  ? 50.592  4.106   100.364 1.00 43.44  ? 69  VAL E CG1 1 
ATOM   11467 C CG2 . VAL E 1 50  ? 51.513  5.143   98.360  1.00 43.66  ? 69  VAL E CG2 1 
ATOM   11468 N N   . ALA E 1 51  ? 47.558  3.069   99.250  1.00 41.58  ? 70  ALA E N   1 
ATOM   11469 C CA  . ALA E 1 51  ? 46.720  2.337   100.196 1.00 41.19  ? 70  ALA E CA  1 
ATOM   11470 C C   . ALA E 1 51  ? 46.181  1.047   99.598  1.00 40.59  ? 70  ALA E C   1 
ATOM   11471 O O   . ALA E 1 51  ? 45.840  0.110   100.315 1.00 40.25  ? 70  ALA E O   1 
ATOM   11472 C CB  . ALA E 1 51  ? 45.567  3.219   100.643 1.00 43.20  ? 70  ALA E CB  1 
ATOM   11473 N N   . THR E 1 52  ? 46.061  1.001   98.299  1.00 40.90  ? 71  THR E N   1 
ATOM   11474 C CA  . THR E 1 52  ? 45.518  -0.120  97.580  1.00 41.02  ? 71  THR E CA  1 
ATOM   11475 C C   . THR E 1 52  ? 46.578  -1.158  97.319  1.00 39.70  ? 71  THR E C   1 
ATOM   11476 O O   . THR E 1 52  ? 46.250  -2.329  97.183  1.00 40.30  ? 71  THR E O   1 
ATOM   11477 C CB  . THR E 1 52  ? 44.869  0.426   96.296  1.00 43.01  ? 71  THR E CB  1 
ATOM   11478 O OG1 . THR E 1 52  ? 43.920  -0.525  95.806  1.00 43.80  ? 71  THR E OG1 1 
ATOM   11479 C CG2 . THR E 1 52  ? 45.861  0.711   95.204  1.00 44.02  ? 71  THR E CG2 1 
ATOM   11480 N N   . ARG E 1 53  ? 47.844  -0.774  97.342  1.00 39.77  ? 72  ARG E N   1 
ATOM   11481 C CA  . ARG E 1 53  ? 48.926  -1.686  97.008  1.00 38.54  ? 72  ARG E CA  1 
ATOM   11482 C C   . ARG E 1 53  ? 49.715  -2.188  98.208  1.00 37.30  ? 72  ARG E C   1 
ATOM   11483 O O   . ARG E 1 53  ? 50.585  -3.044  98.033  1.00 36.55  ? 72  ARG E O   1 
ATOM   11484 C CB  . ARG E 1 53  ? 49.890  -1.000  96.039  1.00 38.80  ? 72  ARG E CB  1 
ATOM   11485 C CG  . ARG E 1 53  ? 49.248  -0.701  94.734  1.00 40.49  ? 72  ARG E CG  1 
ATOM   11486 C CD  . ARG E 1 53  ? 50.235  -0.104  93.732  1.00 41.06  ? 72  ARG E CD  1 
ATOM   11487 N NE  . ARG E 1 53  ? 49.657  -0.183  92.394  1.00 42.61  ? 72  ARG E NE  1 
ATOM   11488 C CZ  . ARG E 1 53  ? 48.528  0.417   92.035  1.00 44.65  ? 72  ARG E CZ  1 
ATOM   11489 N NH1 . ARG E 1 53  ? 47.910  1.270   92.845  1.00 45.49  ? 72  ARG E NH1 1 
ATOM   11490 N NH2 . ARG E 1 53  ? 47.997  0.143   90.844  1.00 46.56  ? 72  ARG E NH2 1 
ATOM   11491 N N   . SER E 1 54  ? 49.433  -1.697  99.404  1.00 38.59  ? 73  SER E N   1 
ATOM   11492 C CA  . SER E 1 54  ? 50.220  -2.116  100.536 1.00 38.01  ? 73  SER E CA  1 
ATOM   11493 C C   . SER E 1 54  ? 49.469  -1.875  101.817 1.00 39.07  ? 73  SER E C   1 
ATOM   11494 O O   . SER E 1 54  ? 48.659  -0.961  101.909 1.00 40.40  ? 73  SER E O   1 
ATOM   11495 C CB  . SER E 1 54  ? 51.540  -1.360  100.614 1.00 37.60  ? 73  SER E CB  1 
ATOM   11496 O OG  . SER E 1 54  ? 52.233  -1.751  101.782 1.00 37.49  ? 73  SER E OG  1 
ATOM   11497 N N   . ASN E 1 55  ? 49.794  -2.672  102.822 1.00 39.25  ? 74  ASN E N   1 
ATOM   11498 C CA  . ASN E 1 55  ? 49.265  -2.496  104.164 1.00 40.02  ? 74  ASN E CA  1 
ATOM   11499 C C   . ASN E 1 55  ? 50.315  -2.028  105.160 1.00 40.13  ? 74  ASN E C   1 
ATOM   11500 O O   . ASN E 1 55  ? 50.095  -2.153  106.367 1.00 41.18  ? 74  ASN E O   1 
ATOM   11501 C CB  . ASN E 1 55  ? 48.654  -3.805  104.676 1.00 40.45  ? 74  ASN E CB  1 
ATOM   11502 C CG  . ASN E 1 55  ? 47.483  -4.234  103.882 1.00 41.08  ? 74  ASN E CG  1 
ATOM   11503 O OD1 . ASN E 1 55  ? 46.871  -3.422  103.209 1.00 42.03  ? 74  ASN E OD1 1 
ATOM   11504 N ND2 . ASN E 1 55  ? 47.159  -5.509  103.939 1.00 42.11  ? 74  ASN E ND2 1 
ATOM   11505 N N   . PHE E 1 56  ? 51.451  -1.514  104.692 1.00 39.47  ? 75  PHE E N   1 
ATOM   11506 C CA  . PHE E 1 56  ? 52.605  -1.279  105.566 1.00 39.19  ? 75  PHE E CA  1 
ATOM   11507 C C   . PHE E 1 56  ? 53.403  -0.096  105.035 1.00 39.30  ? 75  PHE E C   1 
ATOM   11508 O O   . PHE E 1 56  ? 54.007  -0.181  103.969 1.00 38.59  ? 75  PHE E O   1 
ATOM   11509 C CB  . PHE E 1 56  ? 53.451  -2.555  105.622 1.00 38.83  ? 75  PHE E CB  1 
ATOM   11510 C CG  . PHE E 1 56  ? 54.409  -2.621  106.747 1.00 39.35  ? 75  PHE E CG  1 
ATOM   11511 C CD1 . PHE E 1 56  ? 54.307  -1.792  107.845 1.00 40.74  ? 75  PHE E CD1 1 
ATOM   11512 C CD2 . PHE E 1 56  ? 55.424  -3.544  106.710 1.00 39.09  ? 75  PHE E CD2 1 
ATOM   11513 C CE1 . PHE E 1 56  ? 55.208  -1.874  108.864 1.00 41.66  ? 75  PHE E CE1 1 
ATOM   11514 C CE2 . PHE E 1 56  ? 56.349  -3.612  107.744 1.00 40.08  ? 75  PHE E CE2 1 
ATOM   11515 C CZ  . PHE E 1 56  ? 56.227  -2.778  108.819 1.00 41.39  ? 75  PHE E CZ  1 
ATOM   11516 N N   . ILE E 1 57  ? 53.435  1.002   105.768 1.00 40.00  ? 76  ILE E N   1 
ATOM   11517 C CA  . ILE E 1 57  ? 54.147  2.180   105.271 1.00 40.16  ? 76  ILE E CA  1 
ATOM   11518 C C   . ILE E 1 57  ? 54.828  2.892   106.429 1.00 41.26  ? 76  ILE E C   1 
ATOM   11519 O O   . ILE E 1 57  ? 54.222  3.088   107.483 1.00 42.61  ? 76  ILE E O   1 
ATOM   11520 C CB  . ILE E 1 57  ? 53.202  3.145   104.509 1.00 40.99  ? 76  ILE E CB  1 
ATOM   11521 C CG1 . ILE E 1 57  ? 53.969  4.364   103.968 1.00 41.86  ? 76  ILE E CG1 1 
ATOM   11522 C CG2 . ILE E 1 57  ? 51.973  3.565   105.364 1.00 42.42  ? 76  ILE E CG2 1 
ATOM   11523 C CD1 . ILE E 1 57  ? 53.256  5.109   102.854 1.00 43.00  ? 76  ILE E CD1 1 
ATOM   11524 N N   . CYS E 1 58  ? 56.090  3.238   106.258 1.00 43.01  ? 77  CYS E N   1 
ATOM   11525 C CA  A CYS E 1 58  ? 56.787  4.110   107.188 0.45 44.28  ? 77  CYS E CA  1 
ATOM   11526 C CA  B CYS E 1 58  ? 56.783  4.129   107.187 0.55 44.28  ? 77  CYS E CA  1 
ATOM   11527 C C   . CYS E 1 58  ? 56.908  5.484   106.527 1.00 45.50  ? 77  CYS E C   1 
ATOM   11528 O O   . CYS E 1 58  ? 57.540  5.609   105.474 1.00 44.88  ? 77  CYS E O   1 
ATOM   11529 C CB  A CYS E 1 58  ? 58.144  3.498   107.554 0.45 44.21  ? 77  CYS E CB  1 
ATOM   11530 C CB  B CYS E 1 58  ? 58.176  3.647   107.581 0.55 44.21  ? 77  CYS E CB  1 
ATOM   11531 S SG  A CYS E 1 58  ? 58.135  1.713   108.180 0.45 44.28  ? 77  CYS E SG  1 
ATOM   11532 S SG  B CYS E 1 58  ? 59.104  5.021   108.479 0.55 44.28  ? 77  CYS E SG  1 
ATOM   11533 N N   . LEU E 1 59  ? 56.304  6.501   107.141 1.00 45.56  ? 78  LEU E N   1 
ATOM   11534 C CA  . LEU E 1 59  ? 56.426  7.868   106.632 1.00 47.15  ? 78  LEU E CA  1 
ATOM   11535 C C   . LEU E 1 59  ? 57.734  8.448   107.152 1.00 48.27  ? 78  LEU E C   1 
ATOM   11536 O O   . LEU E 1 59  ? 58.062  8.277   108.334 1.00 49.12  ? 78  LEU E O   1 
ATOM   11537 C CB  . LEU E 1 59  ? 55.241  8.734   107.052 1.00 49.10  ? 78  LEU E CB  1 
ATOM   11538 C CG  . LEU E 1 59  ? 53.908  8.326   106.427 1.00 48.36  ? 78  LEU E CG  1 
ATOM   11539 C CD1 . LEU E 1 59  ? 52.740  9.031   107.091 1.00 49.76  ? 78  LEU E CD1 1 
ATOM   11540 C CD2 . LEU E 1 59  ? 53.810  8.594   104.941 1.00 48.54  ? 78  LEU E CD2 1 
ATOM   11541 N N   . GLU E 1 60  ? 58.482  9.112   106.269 1.00 49.73  ? 79  GLU E N   1 
ATOM   11542 C CA  . GLU E 1 60  ? 59.807  9.613   106.598 1.00 50.60  ? 79  GLU E CA  1 
ATOM   11543 C C   . GLU E 1 60  ? 59.773  11.046  107.153 1.00 54.09  ? 79  GLU E C   1 
ATOM   11544 O O   . GLU E 1 60  ? 58.772  11.762  107.081 1.00 56.11  ? 79  GLU E O   1 
ATOM   11545 C CB  . GLU E 1 60  ? 60.719  9.557   105.364 1.00 50.01  ? 79  GLU E CB  1 
ATOM   11546 C CG  . GLU E 1 60  ? 61.689  8.369   105.339 1.00 48.29  ? 79  GLU E CG  1 
ATOM   11547 C CD  . GLU E 1 60  ? 62.917  8.524   106.274 1.00 49.28  ? 79  GLU E CD  1 
ATOM   11548 O OE1 . GLU E 1 60  ? 63.160  9.641   106.800 1.00 51.50  ? 79  GLU E OE1 1 
ATOM   11549 O OE2 . GLU E 1 60  ? 63.647  7.504   106.491 1.00 48.45  ? 79  GLU E OE2 1 
ATOM   11550 N N   . LYS E 1 61  ? 60.913  11.443  107.716 1.00 52.80  ? 80  LYS E N   1 
ATOM   11551 C CA  . LYS E 1 61  ? 61.106  12.804  108.190 1.00 56.26  ? 80  LYS E CA  1 
ATOM   11552 C C   . LYS E 1 61  ? 60.850  13.783  107.055 1.00 58.31  ? 80  LYS E C   1 
ATOM   11553 O O   . LYS E 1 61  ? 61.170  13.521  105.889 1.00 56.98  ? 80  LYS E O   1 
ATOM   11554 C CB  . LYS E 1 61  ? 62.519  12.982  108.745 1.00 57.04  ? 80  LYS E CB  1 
ATOM   11555 C CG  . LYS E 1 61  ? 63.602  12.811  107.695 1.00 56.25  ? 80  LYS E CG  1 
ATOM   11556 C CD  . LYS E 1 61  ? 65.003  12.783  108.277 1.00 56.58  ? 80  LYS E CD  1 
ATOM   11557 C CE  . LYS E 1 61  ? 65.905  11.956  107.370 1.00 54.72  ? 80  LYS E CE  1 
ATOM   11558 N NZ  . LYS E 1 61  ? 65.707  10.453  107.523 1.00 52.86  ? 80  LYS E NZ  1 
ATOM   11559 N N   . GLY E 1 62  ? 60.219  14.903  107.405 1.00 59.03  ? 81  GLY E N   1 
ATOM   11560 C CA  . GLY E 1 62  ? 59.892  15.930  106.454 1.00 59.45  ? 81  GLY E CA  1 
ATOM   11561 C C   . GLY E 1 62  ? 58.509  15.838  105.874 1.00 58.75  ? 81  GLY E C   1 
ATOM   11562 O O   . GLY E 1 62  ? 58.084  16.769  105.180 1.00 59.81  ? 81  GLY E O   1 
ATOM   11563 N N   . HIS E 1 63  ? 57.768  14.780  106.173 1.00 59.31  ? 82  HIS E N   1 
ATOM   11564 C CA  . HIS E 1 63  ? 56.567  14.513  105.399 1.00 57.95  ? 82  HIS E CA  1 
ATOM   11565 C C   . HIS E 1 63  ? 55.519  15.629  105.538 1.00 59.67  ? 82  HIS E C   1 
ATOM   11566 O O   . HIS E 1 63  ? 55.018  15.907  106.629 1.00 60.87  ? 82  HIS E O   1 
ATOM   11567 C CB  . HIS E 1 63  ? 55.960  13.164  105.791 1.00 55.63  ? 82  HIS E CB  1 
ATOM   11568 C CG  . HIS E 1 63  ? 54.763  12.826  104.973 1.00 54.29  ? 82  HIS E CG  1 
ATOM   11569 N ND1 . HIS E 1 63  ? 54.865  12.418  103.667 1.00 53.36  ? 82  HIS E ND1 1 
ATOM   11570 C CD2 . HIS E 1 63  ? 53.437  12.944  105.230 1.00 54.48  ? 82  HIS E CD2 1 
ATOM   11571 C CE1 . HIS E 1 63  ? 53.655  12.249  103.166 1.00 52.94  ? 82  HIS E CE1 1 
ATOM   11572 N NE2 . HIS E 1 63  ? 52.770  12.568  104.093 1.00 53.47  ? 82  HIS E NE2 1 
ATOM   11573 N N   . ALA E 1 64  ? 55.183  16.245  104.402 1.00 57.84  ? 83  ALA E N   1 
ATOM   11574 C CA  . ALA E 1 64  ? 54.101  17.226  104.298 1.00 59.32  ? 83  ALA E CA  1 
ATOM   11575 C C   . ALA E 1 64  ? 54.407  18.487  105.098 1.00 62.20  ? 83  ALA E C   1 
ATOM   11576 O O   . ALA E 1 64  ? 53.493  19.202  105.520 1.00 64.18  ? 83  ALA E O   1 
ATOM   11577 C CB  . ALA E 1 64  ? 52.751  16.647  104.735 1.00 58.97  ? 83  ALA E CB  1 
ATOM   11578 N N   . THR E 1 65  ? 55.702  18.781  105.294 1.00 61.92  ? 84  THR E N   1 
ATOM   11579 C CA  . THR E 1 65  ? 56.065  19.940  106.117 1.00 64.23  ? 84  THR E CA  1 
ATOM   11580 C C   . THR E 1 65  ? 55.735  21.262  105.428 1.00 66.55  ? 84  THR E C   1 
ATOM   11581 O O   . THR E 1 65  ? 55.371  22.225  106.112 1.00 69.01  ? 84  THR E O   1 
ATOM   11582 C CB  . THR E 1 65  ? 57.547  19.886  106.508 1.00 64.77  ? 84  THR E CB  1 
ATOM   11583 O OG1 . THR E 1 65  ? 58.359  19.540  105.378 1.00 64.03  ? 84  THR E OG1 1 
ATOM   11584 C CG2 . THR E 1 65  ? 57.756  18.826  107.588 1.00 63.60  ? 84  THR E CG2 1 
ATOM   11585 N N   . ARG E 1 66  ? 55.802  21.323  104.086 1.00 63.35  ? 85  ARG E N   1 
ATOM   11586 C CA  . ARG E 1 66  ? 55.504  22.578  103.391 1.00 65.54  ? 85  ARG E CA  1 
ATOM   11587 C C   . ARG E 1 66  ? 54.107  23.081  103.723 1.00 67.07  ? 85  ARG E C   1 
ATOM   11588 O O   . ARG E 1 66  ? 53.885  24.294  103.772 1.00 70.87  ? 85  ARG E O   1 
ATOM   11589 C CB  . ARG E 1 66  ? 55.630  22.439  101.872 1.00 64.81  ? 85  ARG E CB  1 
ATOM   11590 N N   . THR E 1 67  ? 53.155  22.173  103.963 1.00 66.11  ? 86  THR E N   1 
ATOM   11591 C CA  . THR E 1 67  ? 51.784  22.561  104.269 1.00 67.49  ? 86  THR E CA  1 
ATOM   11592 C C   . THR E 1 67  ? 51.386  22.367  105.720 1.00 67.85  ? 86  THR E C   1 
ATOM   11593 O O   . THR E 1 67  ? 50.494  23.071  106.197 1.00 70.33  ? 86  THR E O   1 
ATOM   11594 C CB  . THR E 1 67  ? 50.805  21.775  103.396 1.00 66.23  ? 86  THR E CB  1 
ATOM   11595 O OG1 . THR E 1 67  ? 50.838  20.389  103.765 1.00 63.88  ? 86  THR E OG1 1 
ATOM   11596 C CG2 . THR E 1 67  ? 51.200  21.890  101.943 1.00 65.55  ? 86  THR E CG2 1 
ATOM   11597 N N   . HIS E 1 68  ? 52.026  21.444  106.432 1.00 66.75  ? 87  HIS E N   1 
ATOM   11598 C CA  . HIS E 1 68  ? 51.654  21.135  107.802 1.00 66.95  ? 87  HIS E CA  1 
ATOM   11599 C C   . HIS E 1 68  ? 52.664  21.586  108.840 1.00 68.50  ? 87  HIS E C   1 
ATOM   11600 O O   . HIS E 1 68  ? 52.351  21.540  110.033 1.00 69.30  ? 87  HIS E O   1 
ATOM   11601 C CB  . HIS E 1 68  ? 51.402  19.629  107.956 1.00 64.30  ? 87  HIS E CB  1 
ATOM   11602 C CG  . HIS E 1 68  ? 50.109  19.214  107.351 1.00 63.31  ? 87  HIS E CG  1 
ATOM   11603 N ND1 . HIS E 1 68  ? 49.923  19.162  105.988 1.00 63.06  ? 87  HIS E ND1 1 
ATOM   11604 C CD2 . HIS E 1 68  ? 48.907  18.933  107.905 1.00 63.57  ? 87  HIS E CD2 1 
ATOM   11605 C CE1 . HIS E 1 68  ? 48.675  18.816  105.725 1.00 62.61  ? 87  HIS E CE1 1 
ATOM   11606 N NE2 . HIS E 1 68  ? 48.036  18.667  106.871 1.00 63.03  ? 87  HIS E NE2 1 
ATOM   11607 N N   . GLY E 1 69  ? 53.852  22.012  108.432 1.00 66.71  ? 88  GLY E N   1 
ATOM   11608 C CA  . GLY E 1 69  ? 54.730  22.712  109.348 1.00 68.95  ? 88  GLY E CA  1 
ATOM   11609 C C   . GLY E 1 69  ? 55.707  21.821  110.083 1.00 66.45  ? 88  GLY E C   1 
ATOM   11610 O O   . GLY E 1 69  ? 56.922  22.029  109.998 1.00 66.50  ? 88  GLY E O   1 
ATOM   11611 N N   . THR E 1 70  ? 55.191  20.838  110.815 1.00 66.90  ? 89  THR E N   1 
ATOM   11612 C CA  . THR E 1 70  ? 56.017  19.858  111.507 1.00 65.94  ? 89  THR E CA  1 
ATOM   11613 C C   . THR E 1 70  ? 55.869  18.488  110.870 1.00 63.29  ? 89  THR E C   1 
ATOM   11614 O O   . THR E 1 70  ? 54.859  18.182  110.234 1.00 62.28  ? 89  THR E O   1 
ATOM   11615 C CB  . THR E 1 70  ? 55.658  19.756  112.995 1.00 67.10  ? 89  THR E CB  1 
ATOM   11616 O OG1 . THR E 1 70  ? 54.329  19.248  113.158 1.00 66.40  ? 89  THR E OG1 1 
ATOM   11617 C CG2 . THR E 1 70  ? 55.769  21.113  113.626 1.00 69.85  ? 89  THR E CG2 1 
ATOM   11618 N N   . THR E 1 71  ? 56.891  17.661  111.035 1.00 65.01  ? 90  THR E N   1 
ATOM   11619 C CA  . THR E 1 71  ? 56.787  16.301  110.512 1.00 62.51  ? 90  THR E CA  1 
ATOM   11620 C C   . THR E 1 71  ? 55.706  15.522  111.257 1.00 61.86  ? 90  THR E C   1 
ATOM   11621 O O   . THR E 1 71  ? 54.925  14.775  110.647 1.00 59.97  ? 90  THR E O   1 
ATOM   11622 C CB  . THR E 1 71  ? 58.135  15.596  110.601 1.00 61.99  ? 90  THR E CB  1 
ATOM   11623 O OG1 . THR E 1 71  ? 59.084  16.262  109.756 1.00 62.55  ? 90  THR E OG1 1 
ATOM   11624 C CG2 . THR E 1 71  ? 58.003  14.159  110.133 1.00 58.96  ? 90  THR E CG2 1 
ATOM   11625 N N   . GLU E 1 72  ? 55.621  15.716  112.571 1.00 63.33  ? 91  GLU E N   1 
ATOM   11626 C CA  . GLU E 1 72  ? 54.595  15.031  113.348 1.00 62.63  ? 91  GLU E CA  1 
ATOM   11627 C C   . GLU E 1 72  ? 53.198  15.364  112.844 1.00 62.55  ? 91  GLU E C   1 
ATOM   11628 O O   . GLU E 1 72  ? 52.340  14.476  112.746 1.00 60.96  ? 91  GLU E O   1 
ATOM   11629 C CB  . GLU E 1 72  ? 54.738  15.411  114.821 1.00 65.18  ? 91  GLU E CB  1 
ATOM   11630 C CG  . GLU E 1 72  ? 56.105  15.082  115.415 1.00 65.91  ? 91  GLU E CG  1 
ATOM   11631 C CD  . GLU E 1 72  ? 57.003  16.309  115.501 1.00 67.60  ? 91  GLU E CD  1 
ATOM   11632 O OE1 . GLU E 1 72  ? 56.817  17.205  114.637 1.00 67.75  ? 91  GLU E OE1 1 
ATOM   11633 O OE2 . GLU E 1 72  ? 57.876  16.384  116.419 1.00 69.16  ? 91  GLU E OE2 1 
ATOM   11634 N N   . ALA E 1 73  ? 52.949  16.641  112.534 1.00 63.03  ? 92  ALA E N   1 
ATOM   11635 C CA  . ALA E 1 73  ? 51.645  17.041  112.012 1.00 63.15  ? 92  ALA E CA  1 
ATOM   11636 C C   . ALA E 1 73  ? 51.429  16.518  110.594 1.00 60.91  ? 92  ALA E C   1 
ATOM   11637 O O   . ALA E 1 73  ? 50.313  16.128  110.237 1.00 60.21  ? 92  ALA E O   1 
ATOM   11638 C CB  . ALA E 1 73  ? 51.504  18.560  112.033 1.00 66.09  ? 92  ALA E CB  1 
ATOM   11639 N N   . GLY E 1 74  ? 52.474  16.527  109.763 1.00 62.22  ? 93  GLY E N   1 
ATOM   11640 C CA  . GLY E 1 74  ? 52.348  15.936  108.441 1.00 60.57  ? 93  GLY E CA  1 
ATOM   11641 C C   . GLY E 1 74  ? 51.983  14.468  108.507 1.00 57.80  ? 93  GLY E C   1 
ATOM   11642 O O   . GLY E 1 74  ? 51.020  14.018  107.875 1.00 56.79  ? 93  GLY E O   1 
ATOM   11643 N N   . ILE E 1 75  ? 52.731  13.705  109.306 1.00 58.17  ? 94  ILE E N   1 
ATOM   11644 C CA  . ILE E 1 75  ? 52.505  12.265  109.396 1.00 55.68  ? 94  ILE E CA  1 
ATOM   11645 C C   . ILE E 1 75  ? 51.113  11.959  109.941 1.00 55.75  ? 94  ILE E C   1 
ATOM   11646 O O   . ILE E 1 75  ? 50.433  11.044  109.465 1.00 54.14  ? 94  ILE E O   1 
ATOM   11647 C CB  . ILE E 1 75  ? 53.613  11.617  110.248 1.00 54.93  ? 94  ILE E CB  1 
ATOM   11648 C CG1 . ILE E 1 75  ? 54.896  11.563  109.418 1.00 54.40  ? 94  ILE E CG1 1 
ATOM   11649 C CG2 . ILE E 1 75  ? 53.183  10.255  110.736 1.00 53.18  ? 94  ILE E CG2 1 
ATOM   11650 C CD1 . ILE E 1 75  ? 56.040  10.898  110.099 1.00 53.81  ? 94  ILE E CD1 1 
ATOM   11651 N N   . GLU E 1 76  ? 50.671  12.703  110.946 1.00 56.16  ? 95  GLU E N   1 
ATOM   11652 C CA  . GLU E 1 76  ? 49.368  12.418  111.544 1.00 56.44  ? 95  GLU E CA  1 
ATOM   11653 C C   . GLU E 1 76  ? 48.244  12.596  110.526 1.00 55.96  ? 95  GLU E C   1 
ATOM   11654 O O   . GLU E 1 76  ? 47.306  11.787  110.471 1.00 55.10  ? 95  GLU E O   1 
ATOM   11655 C CB  . GLU E 1 76  ? 49.156  13.320  112.764 1.00 59.45  ? 95  GLU E CB  1 
ATOM   11656 C CG  . GLU E 1 76  ? 47.816  13.170  113.451 1.00 59.80  ? 95  GLU E CG  1 
ATOM   11657 C CD  . GLU E 1 76  ? 47.587  11.775  114.014 1.00 58.57  ? 95  GLU E CD  1 
ATOM   11658 O OE1 . GLU E 1 76  ? 48.578  11.000  114.109 1.00 60.39  ? 95  GLU E OE1 1 
ATOM   11659 O OE2 . GLU E 1 76  ? 46.419  11.451  114.364 1.00 56.21  ? 95  GLU E OE2 1 
ATOM   11660 N N   . ALA E 1 77  ? 48.320  13.660  109.717 1.00 56.26  ? 96  ALA E N   1 
ATOM   11661 C CA  . ALA E 1 77  ? 47.287  13.918  108.725 1.00 56.33  ? 96  ALA E CA  1 
ATOM   11662 C C   . ALA E 1 77  ? 47.301  12.858  107.637 1.00 54.19  ? 96  ALA E C   1 
ATOM   11663 O O   . ALA E 1 77  ? 46.250  12.544  107.062 1.00 53.69  ? 96  ALA E O   1 
ATOM   11664 C CB  . ALA E 1 77  ? 47.484  15.312  108.121 1.00 58.76  ? 96  ALA E CB  1 
ATOM   11665 N N   . GLU E 1 78  ? 48.484  12.319  107.359 1.00 56.59  ? 97  GLU E N   1 
ATOM   11666 C CA  . GLU E 1 78  ? 48.635  11.307  106.330 1.00 54.44  ? 97  GLU E CA  1 
ATOM   11667 C C   . GLU E 1 78  ? 48.055  9.984   106.799 1.00 52.56  ? 97  GLU E C   1 
ATOM   11668 O O   . GLU E 1 78  ? 47.245  9.359   106.109 1.00 51.88  ? 97  GLU E O   1 
ATOM   11669 C CB  . GLU E 1 78  ? 50.113  11.153  105.984 1.00 53.80  ? 97  GLU E CB  1 
ATOM   11670 C CG  . GLU E 1 78  ? 50.323  10.320  104.760 1.00 51.87  ? 97  GLU E CG  1 
ATOM   11671 C CD  . GLU E 1 78  ? 49.723  10.992  103.530 1.00 53.10  ? 97  GLU E CD  1 
ATOM   11672 O OE1 . GLU E 1 78  ? 50.287  12.018  103.084 1.00 53.75  ? 97  GLU E OE1 1 
ATOM   11673 O OE2 . GLU E 1 78  ? 48.668  10.511  103.022 1.00 53.79  ? 97  GLU E OE2 1 
ATOM   11674 N N   . ALA E 1 79  ? 48.485  9.537   107.975 1.00 52.74  ? 98  ALA E N   1 
ATOM   11675 C CA  . ALA E 1 79  ? 47.933  8.327   108.554 1.00 51.46  ? 98  ALA E CA  1 
ATOM   11676 C C   . ALA E 1 79  ? 46.426  8.379   108.512 1.00 51.86  ? 98  ALA E C   1 
ATOM   11677 O O   . ALA E 1 79  ? 45.763  7.377   108.228 1.00 51.09  ? 98  ALA E O   1 
ATOM   11678 C CB  . ALA E 1 79  ? 48.428  8.180   109.990 1.00 52.53  ? 98  ALA E CB  1 
ATOM   11679 N N   . ARG E 1 80  ? 45.872  9.558   108.788 1.00 50.72  ? 99  ARG E N   1 
ATOM   11680 C CA  . ARG E 1 80  ? 44.426  9.736   108.754 1.00 51.56  ? 99  ARG E CA  1 
ATOM   11681 C C   . ARG E 1 80  ? 43.894  9.512   107.341 1.00 50.88  ? 99  ARG E C   1 
ATOM   11682 O O   . ARG E 1 80  ? 42.890  8.824   107.160 1.00 50.64  ? 99  ARG E O   1 
ATOM   11683 C CB  . ARG E 1 80  ? 44.058  11.126  109.304 1.00 54.69  ? 99  ARG E CB  1 
ATOM   11684 N N   . GLN E 1 81  ? 44.572  10.044  106.317 1.00 51.29  ? 100 GLN E N   1 
ATOM   11685 C CA  . GLN E 1 81  ? 43.982  9.914   104.988 1.00 51.09  ? 100 GLN E CA  1 
ATOM   11686 C C   . GLN E 1 81  ? 44.230  8.529   104.408 1.00 48.82  ? 100 GLN E C   1 
ATOM   11687 O O   . GLN E 1 81  ? 43.341  8.001   103.739 1.00 48.66  ? 100 GLN E O   1 
ATOM   11688 C CB  . GLN E 1 81  ? 44.459  11.029  104.029 1.00 53.13  ? 100 GLN E CB  1 
ATOM   11689 C CG  . GLN E 1 81  ? 45.767  10.819  103.243 1.00 52.69  ? 100 GLN E CG  1 
ATOM   11690 C CD  . GLN E 1 81  ? 45.900  11.748  101.976 1.00 54.10  ? 100 GLN E CD  1 
ATOM   11691 O OE1 . GLN E 1 81  ? 44.911  12.089  101.315 1.00 53.92  ? 100 GLN E OE1 1 
ATOM   11692 N NE2 . GLN E 1 81  ? 47.162  12.130  101.651 1.00 55.80  ? 100 GLN E NE2 1 
ATOM   11693 N N   . LEU E 1 82  ? 45.398  7.927   104.682 1.00 49.70  ? 101 LEU E N   1 
ATOM   11694 C CA  . LEU E 1 82  ? 45.698  6.585   104.186 1.00 47.70  ? 101 LEU E CA  1 
ATOM   11695 C C   . LEU E 1 82  ? 44.754  5.547   104.787 1.00 47.18  ? 101 LEU E C   1 
ATOM   11696 O O   . LEU E 1 82  ? 44.200  4.711   104.067 1.00 46.46  ? 101 LEU E O   1 
ATOM   11697 C CB  . LEU E 1 82  ? 47.149  6.210   104.470 1.00 46.50  ? 101 LEU E CB  1 
ATOM   11698 C CG  . LEU E 1 82  ? 48.259  6.886   103.660 1.00 46.71  ? 101 LEU E CG  1 
ATOM   11699 C CD1 . LEU E 1 82  ? 49.616  6.424   104.187 1.00 45.97  ? 101 LEU E CD1 1 
ATOM   11700 C CD2 . LEU E 1 82  ? 48.239  6.670   102.162 1.00 46.83  ? 101 LEU E CD2 1 
ATOM   11701 N N   . LYS E 1 83  ? 44.497  5.626   106.090 1.00 46.53  ? 102 LYS E N   1 
ATOM   11702 C CA  . LYS E 1 83  ? 43.601  4.649   106.697 1.00 46.33  ? 102 LYS E CA  1 
ATOM   11703 C C   . LYS E 1 83  ? 42.132  4.889   106.370 1.00 47.25  ? 102 LYS E C   1 
ATOM   11704 O O   . LYS E 1 83  ? 41.340  3.952   106.495 1.00 47.00  ? 102 LYS E O   1 
ATOM   11705 C CB  . LYS E 1 83  ? 43.780  4.637   108.210 1.00 47.36  ? 102 LYS E CB  1 
ATOM   11706 C CG  . LYS E 1 83  ? 45.056  3.917   108.688 1.00 46.86  ? 102 LYS E CG  1 
ATOM   11707 C CD  . LYS E 1 83  ? 45.001  3.778   110.201 1.00 49.04  ? 102 LYS E CD  1 
ATOM   11708 C CE  . LYS E 1 83  ? 46.212  3.174   110.825 1.00 48.55  ? 102 LYS E CE  1 
ATOM   11709 N NZ  . LYS E 1 83  ? 46.045  3.252   112.302 1.00 49.50  ? 102 LYS E NZ  1 
ATOM   11710 N N   . ASN E 1 84  ? 41.738  6.119   106.002 1.00 45.16  ? 103 ASN E N   1 
ATOM   11711 C CA  . ASN E 1 84  ? 40.398  6.339   105.458 1.00 46.32  ? 103 ASN E CA  1 
ATOM   11712 C C   . ASN E 1 84  ? 40.198  5.511   104.196 1.00 44.89  ? 103 ASN E C   1 
ATOM   11713 O O   . ASN E 1 84  ? 39.076  5.114   103.862 1.00 45.68  ? 103 ASN E O   1 
ATOM   11714 C CB  . ASN E 1 84  ? 40.183  7.817   105.151 1.00 48.93  ? 103 ASN E CB  1 
ATOM   11715 N N   . LEU E 1 85  ? 41.283  5.255   103.484 1.00 46.52  ? 104 LEU E N   1 
ATOM   11716 C CA  . LEU E 1 85  ? 41.254  4.489   102.253 1.00 45.56  ? 104 LEU E CA  1 
ATOM   11717 C C   . LEU E 1 85  ? 41.380  2.997   102.538 1.00 44.28  ? 104 LEU E C   1 
ATOM   11718 O O   . LEU E 1 85  ? 40.631  2.192   101.989 1.00 44.86  ? 104 LEU E O   1 
ATOM   11719 C CB  . LEU E 1 85  ? 42.404  4.945   101.337 1.00 45.41  ? 104 LEU E CB  1 
ATOM   11720 C CG  . LEU E 1 85  ? 42.354  6.350   100.726 1.00 47.32  ? 104 LEU E CG  1 
ATOM   11721 C CD1 . LEU E 1 85  ? 43.708  6.737   100.159 1.00 47.27  ? 104 LEU E CD1 1 
ATOM   11722 C CD2 . LEU E 1 85  ? 41.347  6.412   99.624  1.00 48.49  ? 104 LEU E CD2 1 
ATOM   11723 N N   . ASN E 1 86  ? 42.341  2.629   103.382 1.00 43.37  ? 105 ASN E N   1 
ATOM   11724 C CA  . ASN E 1 86  ? 42.681  1.241   103.695 1.00 43.52  ? 105 ASN E CA  1 
ATOM   11725 C C   . ASN E 1 86  ? 42.703  1.118   105.220 1.00 42.80  ? 105 ASN E C   1 
ATOM   11726 O O   . ASN E 1 86  ? 43.722  1.452   105.860 1.00 41.50  ? 105 ASN E O   1 
ATOM   11727 C CB  . ASN E 1 86  ? 44.007  0.868   103.049 1.00 42.61  ? 105 ASN E CB  1 
ATOM   11728 C CG  . ASN E 1 86  ? 44.466  -0.513  103.425 1.00 42.60  ? 105 ASN E CG  1 
ATOM   11729 O OD1 . ASN E 1 86  ? 43.775  -1.204  104.131 1.00 43.12  ? 105 ASN E OD1 1 
ATOM   11730 N ND2 . ASN E 1 86  ? 45.647  -0.913  102.961 1.00 41.47  ? 105 ASN E ND2 1 
ATOM   11731 N N   . PRO E 1 87  ? 41.592  0.686   105.825 1.00 44.51  ? 106 PRO E N   1 
ATOM   11732 C CA  . PRO E 1 87  ? 41.547  0.550   107.293 1.00 44.01  ? 106 PRO E CA  1 
ATOM   11733 C C   . PRO E 1 87  ? 42.582  -0.414  107.873 1.00 42.60  ? 106 PRO E C   1 
ATOM   11734 O O   . PRO E 1 87  ? 42.816  -0.390  109.089 1.00 42.70  ? 106 PRO E O   1 
ATOM   11735 C CB  . PRO E 1 87  ? 40.127  0.034   107.574 1.00 45.88  ? 106 PRO E CB  1 
ATOM   11736 C CG  . PRO E 1 87  ? 39.393  0.004   106.273 1.00 47.85  ? 106 PRO E CG  1 
ATOM   11737 C CD  . PRO E 1 87  ? 40.336  0.305   105.149 1.00 46.05  ? 106 PRO E CD  1 
ATOM   11738 N N   . LYS E 1 88  ? 43.160  -1.296  107.064 1.00 46.76  ? 107 LYS E N   1 
ATOM   11739 C CA  . LYS E 1 88  ? 44.158  -2.248  107.521 1.00 45.44  ? 107 LYS E CA  1 
ATOM   11740 C C   . LYS E 1 88  ? 45.570  -1.689  107.424 1.00 43.84  ? 107 LYS E C   1 
ATOM   11741 O O   . LYS E 1 88  ? 46.518  -2.364  107.824 1.00 42.64  ? 107 LYS E O   1 
ATOM   11742 C CB  . LYS E 1 88  ? 44.078  -3.550  106.700 1.00 46.86  ? 107 LYS E CB  1 
ATOM   11743 C CG  . LYS E 1 88  ? 42.732  -4.244  106.692 1.00 49.44  ? 107 LYS E CG  1 
ATOM   11744 C CD  . LYS E 1 88  ? 42.552  -5.040  107.971 1.00 50.16  ? 107 LYS E CD  1 
ATOM   11745 C CE  . LYS E 1 88  ? 41.601  -4.359  108.988 1.00 51.79  ? 107 LYS E CE  1 
ATOM   11746 N NZ  . LYS E 1 88  ? 40.864  -5.346  109.865 1.00 53.52  ? 107 LYS E NZ  1 
ATOM   11747 N N   . MET E 1 89  ? 45.757  -0.485  106.907 1.00 46.45  ? 108 MET E N   1 
ATOM   11748 C CA  . MET E 1 89  ? 47.119  -0.021  106.729 1.00 44.80  ? 108 MET E CA  1 
ATOM   11749 C C   . MET E 1 89  ? 47.802  0.258   108.069 1.00 43.42  ? 108 MET E C   1 
ATOM   11750 O O   . MET E 1 89  ? 47.226  0.847   108.987 1.00 44.88  ? 108 MET E O   1 
ATOM   11751 C CB  . MET E 1 89  ? 47.184  1.239   105.870 1.00 45.67  ? 108 MET E CB  1 
ATOM   11752 C CG  . MET E 1 89  ? 48.518  1.245   105.144 1.00 44.82  ? 108 MET E CG  1 
ATOM   11753 S SD  . MET E 1 89  ? 48.319  1.878   103.504 1.00 45.68  ? 108 MET E SD  1 
ATOM   11754 C CE  . MET E 1 89  ? 50.011  1.832   102.838 1.00 43.61  ? 108 MET E CE  1 
ATOM   11755 N N   . LYS E 1 90  ? 49.045  -0.183  108.149 1.00 47.00  ? 109 LYS E N   1 
ATOM   11756 C CA  . LYS E 1 90  ? 49.923  0.023   109.286 1.00 45.73  ? 109 LYS E CA  1 
ATOM   11757 C C   . LYS E 1 90  ? 50.876  1.145   108.889 1.00 45.02  ? 109 LYS E C   1 
ATOM   11758 O O   . LYS E 1 90  ? 51.682  0.998   107.957 1.00 44.42  ? 109 LYS E O   1 
ATOM   11759 C CB  . LYS E 1 90  ? 50.681  -1.259  109.643 1.00 44.76  ? 109 LYS E CB  1 
ATOM   11760 C CG  . LYS E 1 90  ? 49.772  -2.412  110.043 1.00 45.98  ? 109 LYS E CG  1 
ATOM   11761 C CD  . LYS E 1 90  ? 49.084  -2.118  111.340 1.00 47.19  ? 109 LYS E CD  1 
ATOM   11762 C CE  . LYS E 1 90  ? 48.379  -3.351  111.871 1.00 48.56  ? 109 LYS E CE  1 
ATOM   11763 N NZ  . LYS E 1 90  ? 47.851  -3.066  113.245 1.00 50.09  ? 109 LYS E NZ  1 
ATOM   11764 N N   . VAL E 1 91  ? 50.751  2.269   109.582 1.00 46.69  ? 110 VAL E N   1 
ATOM   11765 C CA  . VAL E 1 91  ? 51.486  3.494   109.300 1.00 46.59  ? 110 VAL E CA  1 
ATOM   11766 C C   . VAL E 1 91  ? 52.481  3.694   110.441 1.00 46.33  ? 110 VAL E C   1 
ATOM   11767 O O   . VAL E 1 91  ? 52.093  3.701   111.623 1.00 47.18  ? 110 VAL E O   1 
ATOM   11768 C CB  . VAL E 1 91  ? 50.525  4.692   109.149 1.00 48.15  ? 110 VAL E CB  1 
ATOM   11769 C CG1 . VAL E 1 91  ? 51.276  5.950   108.705 1.00 48.46  ? 110 VAL E CG1 1 
ATOM   11770 C CG2 . VAL E 1 91  ? 49.390  4.382   108.120 1.00 49.18  ? 110 VAL E CG2 1 
ATOM   11771 N N   . ILE E 1 92  ? 53.763  3.836   110.084 1.00 47.76  ? 111 ILE E N   1 
ATOM   11772 C CA  . ILE E 1 92  ? 54.872  3.810   111.039 1.00 47.66  ? 111 ILE E CA  1 
ATOM   11773 C C   . ILE E 1 92  ? 55.508  5.187   111.117 1.00 48.43  ? 111 ILE E C   1 
ATOM   11774 O O   . ILE E 1 92  ? 56.102  5.650   110.133 1.00 48.39  ? 111 ILE E O   1 
ATOM   11775 C CB  . ILE E 1 92  ? 55.955  2.781   110.658 1.00 46.21  ? 111 ILE E CB  1 
ATOM   11776 C CG1 . ILE E 1 92  ? 55.358  1.423   110.306 1.00 45.70  ? 111 ILE E CG1 1 
ATOM   11777 C CG2 . ILE E 1 92  ? 56.957  2.625   111.805 1.00 46.33  ? 111 ILE E CG2 1 
ATOM   11778 C CD1 . ILE E 1 92  ? 54.554  0.825   111.463 1.00 47.00  ? 111 ILE E CD1 1 
ATOM   11779 N N   . PHE E 1 93  ? 55.455  5.788   112.310 1.00 49.24  ? 112 PHE E N   1 
ATOM   11780 C CA  . PHE E 1 93  ? 56.043  7.106   112.556 1.00 50.65  ? 112 PHE E CA  1 
ATOM   11781 C C   . PHE E 1 93  ? 57.563  7.021   112.621 1.00 50.11  ? 112 PHE E C   1 
ATOM   11782 O O   . PHE E 1 93  ? 58.112  6.302   113.457 1.00 50.43  ? 112 PHE E O   1 
ATOM   11783 C CB  . PHE E 1 93  ? 55.469  7.678   113.859 1.00 52.53  ? 112 PHE E CB  1 
ATOM   11784 C CG  . PHE E 1 93  ? 56.085  8.990   114.282 1.00 54.49  ? 112 PHE E CG  1 
ATOM   11785 C CD1 . PHE E 1 93  ? 55.873  10.130  113.545 1.00 55.70  ? 112 PHE E CD1 1 
ATOM   11786 C CD2 . PHE E 1 93  ? 56.901  9.074   115.416 1.00 56.18  ? 112 PHE E CD2 1 
ATOM   11787 C CE1 . PHE E 1 93  ? 56.459  11.327  113.933 1.00 57.71  ? 112 PHE E CE1 1 
ATOM   11788 C CE2 . PHE E 1 93  ? 57.470  10.265  115.799 1.00 58.46  ? 112 PHE E CE2 1 
ATOM   11789 C CZ  . PHE E 1 93  ? 57.245  11.390  115.064 1.00 58.89  ? 112 PHE E CZ  1 
ATOM   11790 N N   . TYR E 1 94  ? 58.238  7.754   111.731 1.00 51.22  ? 113 TYR E N   1 
ATOM   11791 C CA  . TYR E 1 94  ? 59.699  7.808   111.701 1.00 51.43  ? 113 TYR E CA  1 
ATOM   11792 C C   . TYR E 1 94  ? 60.242  8.702   112.831 1.00 53.95  ? 113 TYR E C   1 
ATOM   11793 O O   . TYR E 1 94  ? 59.917  9.896   112.920 1.00 55.80  ? 113 TYR E O   1 
ATOM   11794 C CB  . TYR E 1 94  ? 60.177  8.334   110.347 1.00 51.38  ? 113 TYR E CB  1 
ATOM   11795 C CG  . TYR E 1 94  ? 61.673  8.472   110.239 1.00 51.75  ? 113 TYR E CG  1 
ATOM   11796 C CD1 . TYR E 1 94  ? 62.356  9.569   110.804 1.00 54.09  ? 113 TYR E CD1 1 
ATOM   11797 C CD2 . TYR E 1 94  ? 62.411  7.502   109.582 1.00 50.12  ? 113 TYR E CD2 1 
ATOM   11798 C CE1 . TYR E 1 94  ? 63.741  9.673   110.713 1.00 54.62  ? 113 TYR E CE1 1 
ATOM   11799 C CE2 . TYR E 1 94  ? 63.791  7.600   109.477 1.00 50.52  ? 113 TYR E CE2 1 
ATOM   11800 C CZ  . TYR E 1 94  ? 64.456  8.682   110.049 1.00 52.61  ? 113 TYR E CZ  1 
ATOM   11801 O OH  . TYR E 1 94  ? 65.836  8.747   109.931 1.00 53.35  ? 113 TYR E OH  1 
ATOM   11802 N N   . TRP E 1 95  ? 61.082  8.134   113.684 1.00 53.67  ? 114 TRP E N   1 
ATOM   11803 C CA  . TRP E 1 95  ? 61.584  8.864   114.841 1.00 56.16  ? 114 TRP E CA  1 
ATOM   11804 C C   . TRP E 1 95  ? 62.997  8.368   115.056 1.00 56.63  ? 114 TRP E C   1 
ATOM   11805 O O   . TRP E 1 95  ? 63.185  7.226   115.486 1.00 55.85  ? 114 TRP E O   1 
ATOM   11806 C CB  . TRP E 1 95  ? 60.676  8.657   116.063 1.00 57.15  ? 114 TRP E CB  1 
ATOM   11807 C CG  . TRP E 1 95  ? 61.042  9.511   117.240 1.00 59.91  ? 114 TRP E CG  1 
ATOM   11808 C CD1 . TRP E 1 95  ? 61.115  9.102   118.535 1.00 61.15  ? 114 TRP E CD1 1 
ATOM   11809 C CD2 . TRP E 1 95  ? 61.392  10.913  117.246 1.00 62.24  ? 114 TRP E CD2 1 
ATOM   11810 N NE1 . TRP E 1 95  ? 61.498  10.144  119.346 1.00 64.05  ? 114 TRP E NE1 1 
ATOM   11811 C CE2 . TRP E 1 95  ? 61.671  11.266  118.580 1.00 64.77  ? 114 TRP E CE2 1 
ATOM   11812 C CE3 . TRP E 1 95  ? 61.489  11.899  116.258 1.00 62.75  ? 114 TRP E CE3 1 
ATOM   11813 C CZ2 . TRP E 1 95  ? 62.056  12.559  118.950 1.00 67.66  ? 114 TRP E CZ2 1 
ATOM   11814 C CZ3 . TRP E 1 95  ? 61.865  13.180  116.627 1.00 65.91  ? 114 TRP E CZ3 1 
ATOM   11815 C CH2 . TRP E 1 95  ? 62.150  13.496  117.959 1.00 68.21  ? 114 TRP E CH2 1 
ATOM   11816 N N   . ASN E 1 96  ? 63.974  9.212   114.703 1.00 55.94  ? 115 ASN E N   1 
ATOM   11817 C CA  . ASN E 1 96  ? 65.372  8.803   114.668 1.00 56.08  ? 115 ASN E CA  1 
ATOM   11818 C C   . ASN E 1 96  ? 65.914  8.625   116.075 1.00 58.13  ? 115 ASN E C   1 
ATOM   11819 O O   . ASN E 1 96  ? 65.817  9.534   116.907 1.00 60.90  ? 115 ASN E O   1 
ATOM   11820 C CB  . ASN E 1 96  ? 66.212  9.835   113.925 1.00 57.36  ? 115 ASN E CB  1 
ATOM   11821 C CG  . ASN E 1 96  ? 67.561  9.304   113.528 1.00 56.96  ? 115 ASN E CG  1 
ATOM   11822 O OD1 . ASN E 1 96  ? 68.401  9.012   114.374 1.00 58.38  ? 115 ASN E OD1 1 
ATOM   11823 N ND2 . ASN E 1 96  ? 67.776  9.163   112.227 1.00 55.49  ? 115 ASN E ND2 1 
ATOM   11824 N N   . THR E 1 97  ? 66.502  7.451   116.324 1.00 56.91  ? 116 THR E N   1 
ATOM   11825 C CA  . THR E 1 97  ? 66.942  7.076   117.659 1.00 58.76  ? 116 THR E CA  1 
ATOM   11826 C C   . THR E 1 97  ? 68.125  7.899   118.134 1.00 62.20  ? 116 THR E C   1 
ATOM   11827 O O   . THR E 1 97  ? 68.395  7.922   119.334 1.00 65.05  ? 116 THR E O   1 
ATOM   11828 C CB  . THR E 1 97  ? 67.353  5.599   117.695 1.00 56.98  ? 116 THR E CB  1 
ATOM   11829 O OG1 . THR E 1 97  ? 66.487  4.842   116.856 1.00 54.04  ? 116 THR E OG1 1 
ATOM   11830 C CG2 . THR E 1 97  ? 67.288  5.038   119.116 1.00 59.07  ? 116 THR E CG2 1 
ATOM   11831 N N   . PHE E 1 98  ? 68.813  8.568   117.214 1.00 59.68  ? 117 PHE E N   1 
ATOM   11832 C CA  . PHE E 1 98  ? 70.146  9.086   117.441 1.00 62.03  ? 117 PHE E CA  1 
ATOM   11833 C C   . PHE E 1 98  ? 70.344  10.537  117.032 1.00 63.35  ? 117 PHE E C   1 
ATOM   11834 O O   . PHE E 1 98  ? 71.289  11.165  117.537 1.00 65.74  ? 117 PHE E O   1 
ATOM   11835 C CB  . PHE E 1 98  ? 71.174  8.239   116.672 1.00 60.59  ? 117 PHE E CB  1 
ATOM   11836 C CG  . PHE E 1 98  ? 72.585  8.326   117.202 1.00 62.60  ? 117 PHE E CG  1 
ATOM   11837 C CD1 . PHE E 1 98  ? 72.841  8.438   118.547 1.00 65.90  ? 117 PHE E CD1 1 
ATOM   11838 C CD2 . PHE E 1 98  ? 73.655  8.242   116.336 1.00 61.95  ? 117 PHE E CD2 1 
ATOM   11839 C CE1 . PHE E 1 98  ? 74.121  8.492   119.005 1.00 67.53  ? 117 PHE E CE1 1 
ATOM   11840 C CE2 . PHE E 1 98  ? 74.942  8.298   116.798 1.00 63.86  ? 117 PHE E CE2 1 
ATOM   11841 C CZ  . PHE E 1 98  ? 75.175  8.424   118.131 1.00 66.53  ? 117 PHE E CZ  1 
ATOM   11842 N N   . LEU E 1 99  ? 69.532  11.085  116.125 1.00 62.27  ? 118 LEU E N   1 
ATOM   11843 C CA  . LEU E 1 99  ? 69.843  12.365  115.509 1.00 63.05  ? 118 LEU E CA  1 
ATOM   11844 C C   . LEU E 1 99  ? 68.679  13.345  115.608 1.00 64.50  ? 118 LEU E C   1 
ATOM   11845 O O   . LEU E 1 99  ? 67.512  12.981  115.395 1.00 63.39  ? 118 LEU E O   1 
ATOM   11846 C CB  . LEU E 1 99  ? 70.234  12.185  114.051 1.00 60.86  ? 118 LEU E CB  1 
ATOM   11847 C CG  . LEU E 1 99  ? 71.158  11.011  113.746 1.00 59.99  ? 118 LEU E CG  1 
ATOM   11848 C CD1 . LEU E 1 99  ? 71.499  10.947  112.276 1.00 58.28  ? 118 LEU E CD1 1 
ATOM   11849 C CD2 . LEU E 1 99  ? 72.394  11.152  114.590 1.00 62.53  ? 118 LEU E CD2 1 
ATOM   11850 N N   . ASP E 1 100 ? 69.043  14.607  115.911 1.00 64.26  ? 119 ASP E N   1 
ATOM   11851 C CA  . ASP E 1 100 ? 68.145  15.728  116.178 1.00 65.98  ? 119 ASP E CA  1 
ATOM   11852 C C   . ASP E 1 100 ? 67.850  16.427  114.863 1.00 65.46  ? 119 ASP E C   1 
ATOM   11853 O O   . ASP E 1 100 ? 68.546  17.342  114.449 1.00 66.66  ? 119 ASP E O   1 
ATOM   11854 C CB  . ASP E 1 100 ? 68.790  16.678  117.184 1.00 68.50  ? 119 ASP E CB  1 
ATOM   11855 C CG  . ASP E 1 100 ? 68.040  17.986  117.320 1.00 70.11  ? 119 ASP E CG  1 
ATOM   11856 O OD1 . ASP E 1 100 ? 66.781  17.963  117.392 1.00 69.62  ? 119 ASP E OD1 1 
ATOM   11857 O OD2 . ASP E 1 100 ? 68.717  19.033  117.355 1.00 72.18  ? 119 ASP E OD2 1 
ATOM   11858 N N   . TYR E 1 101 ? 66.811  15.980  114.188 1.00 65.61  ? 120 TYR E N   1 
ATOM   11859 C CA  . TYR E 1 101 ? 66.442  16.566  112.912 1.00 65.34  ? 120 TYR E CA  1 
ATOM   11860 C C   . TYR E 1 101 ? 65.592  17.812  113.132 1.00 67.12  ? 120 TYR E C   1 
ATOM   11861 O O   . TYR E 1 101 ? 64.747  17.861  114.034 1.00 67.51  ? 120 TYR E O   1 
ATOM   11862 C CB  . TYR E 1 101 ? 65.694  15.539  112.063 1.00 62.78  ? 120 TYR E CB  1 
ATOM   11863 C CG  . TYR E 1 101 ? 66.620  14.568  111.364 1.00 60.18  ? 120 TYR E CG  1 
ATOM   11864 C CD1 . TYR E 1 101 ? 67.295  14.938  110.219 1.00 60.56  ? 120 TYR E CD1 1 
ATOM   11865 C CD2 . TYR E 1 101 ? 66.827  13.283  111.860 1.00 58.61  ? 120 TYR E CD2 1 
ATOM   11866 C CE1 . TYR E 1 101 ? 68.148  14.064  109.587 1.00 58.76  ? 120 TYR E CE1 1 
ATOM   11867 C CE2 . TYR E 1 101 ? 67.677  12.404  111.225 1.00 56.82  ? 120 TYR E CE2 1 
ATOM   11868 C CZ  . TYR E 1 101 ? 68.330  12.806  110.090 1.00 56.84  ? 120 TYR E CZ  1 
ATOM   11869 O OH  . TYR E 1 101 ? 69.189  11.970  109.440 1.00 55.75  ? 120 TYR E OH  1 
ATOM   11870 N N   . SER E 1 102 ? 65.823  18.820  112.286 1.00 65.95  ? 121 SER E N   1 
ATOM   11871 C CA  . SER E 1 102 ? 65.215  20.126  112.490 1.00 67.94  ? 121 SER E CA  1 
ATOM   11872 C C   . SER E 1 102 ? 63.719  20.110  112.244 1.00 66.90  ? 121 SER E C   1 
ATOM   11873 O O   . SER E 1 102 ? 62.968  20.814  112.927 1.00 68.95  ? 121 SER E O   1 
ATOM   11874 C CB  . SER E 1 102 ? 65.831  21.141  111.539 1.00 69.68  ? 121 SER E CB  1 
ATOM   11875 O OG  . SER E 1 102 ? 65.450  20.789  110.219 1.00 68.51  ? 121 SER E OG  1 
ATOM   11876 N N   . MET E 1 103 ? 63.275  19.327  111.272 1.00 67.17  ? 122 MET E N   1 
ATOM   11877 C CA  . MET E 1 103 ? 61.935  19.416  110.709 1.00 65.90  ? 122 MET E CA  1 
ATOM   11878 C C   . MET E 1 103 ? 60.855  18.736  111.578 1.00 64.70  ? 122 MET E C   1 
ATOM   11879 O O   . MET E 1 103 ? 59.783  18.376  111.069 1.00 63.02  ? 122 MET E O   1 
ATOM   11880 C CB  . MET E 1 103 ? 61.957  18.819  109.293 1.00 64.34  ? 122 MET E CB  1 
ATOM   11881 C CG  . MET E 1 103 ? 62.294  17.345  109.233 1.00 62.62  ? 122 MET E CG  1 
ATOM   11882 S SD  . MET E 1 103 ? 64.047  16.909  109.126 1.00 63.12  ? 122 MET E SD  1 
ATOM   11883 C CE  . MET E 1 103 ? 64.657  17.978  107.851 1.00 65.41  ? 122 MET E CE  1 
ATOM   11884 N N   . PHE E 1 104 ? 61.141  18.590  112.870 1.00 67.61  ? 123 PHE E N   1 
ATOM   11885 C CA  . PHE E 1 104 ? 60.198  18.060  113.842 1.00 67.06  ? 123 PHE E CA  1 
ATOM   11886 C C   . PHE E 1 104 ? 59.921  19.123  114.891 1.00 69.56  ? 123 PHE E C   1 
ATOM   11887 O O   . PHE E 1 104 ? 60.819  19.893  115.249 1.00 71.74  ? 123 PHE E O   1 
ATOM   11888 C CB  . PHE E 1 104 ? 60.734  16.812  114.542 1.00 66.18  ? 123 PHE E CB  1 
ATOM   11889 C CG  . PHE E 1 104 ? 60.848  15.631  113.657 1.00 63.14  ? 123 PHE E CG  1 
ATOM   11890 C CD1 . PHE E 1 104 ? 61.867  15.543  112.735 1.00 62.67  ? 123 PHE E CD1 1 
ATOM   11891 C CD2 . PHE E 1 104 ? 59.935  14.601  113.745 1.00 61.31  ? 123 PHE E CD2 1 
ATOM   11892 C CE1 . PHE E 1 104 ? 61.972  14.444  111.917 1.00 60.07  ? 123 PHE E CE1 1 
ATOM   11893 C CE2 . PHE E 1 104 ? 60.038  13.516  112.936 1.00 58.71  ? 123 PHE E CE2 1 
ATOM   11894 C CZ  . PHE E 1 104 ? 61.051  13.438  112.018 1.00 58.06  ? 123 PHE E CZ  1 
ATOM   11895 N N   . ALA E 1 105 ? 58.673  19.154  115.363 1.00 64.89  ? 124 ALA E N   1 
ATOM   11896 C CA  . ALA E 1 105 ? 58.331  19.915  116.556 1.00 68.17  ? 124 ALA E CA  1 
ATOM   11897 C C   . ALA E 1 105 ? 59.270  19.581  117.711 1.00 69.34  ? 124 ALA E C   1 
ATOM   11898 O O   . ALA E 1 105 ? 59.744  20.480  118.413 1.00 72.29  ? 124 ALA E O   1 
ATOM   11899 C CB  . ALA E 1 105 ? 56.875  19.633  116.926 1.00 68.39  ? 124 ALA E CB  1 
ATOM   11900 N N   . ALA E 1 106 ? 59.564  18.294  117.912 1.00 68.44  ? 125 ALA E N   1 
ATOM   11901 C CA  . ALA E 1 106 ? 60.435  17.898  119.008 1.00 69.49  ? 125 ALA E CA  1 
ATOM   11902 C C   . ALA E 1 106 ? 61.710  18.718  118.992 1.00 71.11  ? 125 ALA E C   1 
ATOM   11903 O O   . ALA E 1 106 ? 62.271  19.036  120.054 1.00 73.43  ? 125 ALA E O   1 
ATOM   11904 C CB  . ALA E 1 106 ? 60.758  16.408  118.928 1.00 68.03  ? 125 ALA E CB  1 
ATOM   11905 N N   . HIS E 1 107 ? 62.162  19.106  117.800 1.00 68.21  ? 126 HIS E N   1 
ATOM   11906 C CA  . HIS E 1 107 ? 63.390  19.885  117.696 1.00 69.64  ? 126 HIS E CA  1 
ATOM   11907 C C   . HIS E 1 107 ? 63.386  21.098  118.623 1.00 73.57  ? 126 HIS E C   1 
ATOM   11908 O O   . HIS E 1 107 ? 64.376  21.359  119.315 1.00 75.48  ? 126 HIS E O   1 
ATOM   11909 C CB  . HIS E 1 107 ? 63.589  20.308  116.245 1.00 68.33  ? 126 HIS E CB  1 
ATOM   11910 C CG  . HIS E 1 107 ? 64.794  21.162  116.025 1.00 70.04  ? 126 HIS E CG  1 
ATOM   11911 N ND1 . HIS E 1 107 ? 66.081  20.670  116.105 1.00 69.63  ? 126 HIS E ND1 1 
ATOM   11912 C CD2 . HIS E 1 107 ? 64.908  22.470  115.705 1.00 72.39  ? 126 HIS E CD2 1 
ATOM   11913 C CE1 . HIS E 1 107 ? 66.937  21.642  115.847 1.00 71.57  ? 126 HIS E CE1 1 
ATOM   11914 N NE2 . HIS E 1 107 ? 66.250  22.742  115.596 1.00 73.30  ? 126 HIS E NE2 1 
ATOM   11915 N N   . LYS E 1 108 ? 62.281  21.853  118.652 1.00 68.48  ? 127 LYS E N   1 
ATOM   11916 C CA  . LYS E 1 108 ? 62.222  23.037  119.510 1.00 72.37  ? 127 LYS E CA  1 
ATOM   11917 C C   . LYS E 1 108 ? 62.252  22.670  120.993 1.00 74.23  ? 127 LYS E C   1 
ATOM   11918 O O   . LYS E 1 108 ? 62.672  23.497  121.812 1.00 77.66  ? 127 LYS E O   1 
ATOM   11919 C CB  . LYS E 1 108 ? 60.983  23.872  119.198 1.00 73.45  ? 127 LYS E CB  1 
ATOM   11920 N N   . GLU E 1 109 ? 61.853  21.445  121.360 1.00 74.04  ? 128 GLU E N   1 
ATOM   11921 C CA  . GLU E 1 109 ? 61.968  21.010  122.755 1.00 75.84  ? 128 GLU E CA  1 
ATOM   11922 C C   . GLU E 1 109 ? 63.401  20.603  123.116 1.00 76.11  ? 128 GLU E C   1 
ATOM   11923 O O   . GLU E 1 109 ? 63.930  21.052  124.136 1.00 79.20  ? 128 GLU E O   1 
ATOM   11924 C CB  . GLU E 1 109 ? 60.999  19.853  123.034 1.00 73.93  ? 128 GLU E CB  1 
ATOM   11925 N N   . TYR E 1 110 ? 64.042  19.742  122.300 1.00 74.17  ? 129 TYR E N   1 
ATOM   11926 C CA  . TYR E 1 110 ? 65.411  19.305  122.578 1.00 74.21  ? 129 TYR E CA  1 
ATOM   11927 C C   . TYR E 1 110 ? 66.367  20.477  122.652 1.00 77.18  ? 129 TYR E C   1 
ATOM   11928 O O   . TYR E 1 110 ? 67.467  20.344  123.204 1.00 78.66  ? 129 TYR E O   1 
ATOM   11929 C CB  . TYR E 1 110 ? 65.905  18.335  121.503 1.00 70.41  ? 129 TYR E CB  1 
ATOM   11930 C CG  . TYR E 1 110 ? 67.248  17.676  121.789 1.00 70.13  ? 129 TYR E CG  1 
ATOM   11931 C CD1 . TYR E 1 110 ? 67.361  16.653  122.722 1.00 69.98  ? 129 TYR E CD1 1 
ATOM   11932 C CD2 . TYR E 1 110 ? 68.394  18.053  121.096 1.00 69.97  ? 129 TYR E CD2 1 
ATOM   11933 C CE1 . TYR E 1 110 ? 68.577  16.034  122.967 1.00 69.78  ? 129 TYR E CE1 1 
ATOM   11934 C CE2 . TYR E 1 110 ? 69.622  17.444  121.341 1.00 69.78  ? 129 TYR E CE2 1 
ATOM   11935 C CZ  . TYR E 1 110 ? 69.710  16.433  122.283 1.00 69.67  ? 129 TYR E CZ  1 
ATOM   11936 O OH  . TYR E 1 110 ? 70.925  15.816  122.545 1.00 69.58  ? 129 TYR E OH  1 
ATOM   11937 N N   . ALA E 1 111 ? 65.961  21.612  122.083 1.00 76.08  ? 130 ALA E N   1 
ATOM   11938 C CA  . ALA E 1 111 ? 66.759  22.829  122.111 1.00 79.12  ? 130 ALA E CA  1 
ATOM   11939 C C   . ALA E 1 111 ? 66.832  23.444  123.502 1.00 83.18  ? 130 ALA E C   1 
ATOM   11940 O O   . ALA E 1 111 ? 67.836  24.084  123.840 1.00 85.91  ? 130 ALA E O   1 
ATOM   11941 C CB  . ALA E 1 111 ? 66.162  23.836  121.126 1.00 79.28  ? 130 ALA E CB  1 
ATOM   11942 N N   . LYS E 1 112 ? 65.776  23.288  124.302 1.00 80.38  ? 131 LYS E N   1 
ATOM   11943 C CA  . LYS E 1 112 ? 65.723  23.884  125.631 1.00 87.17  ? 131 LYS E CA  1 
ATOM   11944 C C   . LYS E 1 112 ? 66.468  23.081  126.677 1.00 88.71  ? 131 LYS E C   1 
ATOM   11945 O O   . LYS E 1 112 ? 66.441  23.447  127.850 1.00 94.40  ? 131 LYS E O   1 
ATOM   11946 C CB  . LYS E 1 112 ? 64.283  24.020  126.121 1.00 89.23  ? 131 LYS E CB  1 
ATOM   11947 C CG  . LYS E 1 112 ? 63.309  24.538  125.112 1.00 87.18  ? 131 LYS E CG  1 
ATOM   11948 C CD  . LYS E 1 112 ? 63.641  25.950  124.686 1.00 90.73  ? 131 LYS E CD  1 
ATOM   11949 C CE  . LYS E 1 112 ? 62.867  26.240  123.406 1.00 87.78  ? 131 LYS E CE  1 
ATOM   11950 N NZ  . LYS E 1 112 ? 61.408  25.822  123.477 1.00 86.41  ? 131 LYS E NZ  1 
ATOM   11951 N N   . HIS E 1 113 ? 67.079  21.966  126.309 1.00 86.15  ? 132 HIS E N   1 
ATOM   11952 C CA  . HIS E 1 113 ? 67.751  21.103  127.271 1.00 86.65  ? 132 HIS E CA  1 
ATOM   11953 C C   . HIS E 1 113 ? 69.228  20.991  126.957 1.00 86.25  ? 132 HIS E C   1 
ATOM   11954 O O   . HIS E 1 113 ? 69.734  19.897  126.700 1.00 83.67  ? 132 HIS E O   1 
ATOM   11955 C CB  . HIS E 1 113 ? 67.061  19.756  127.313 1.00 83.56  ? 132 HIS E CB  1 
ATOM   11956 C CG  . HIS E 1 113 ? 65.618  19.884  127.684 1.00 84.27  ? 132 HIS E CG  1 
ATOM   11957 N ND1 . HIS E 1 113 ? 64.687  20.423  126.827 1.00 83.11  ? 132 HIS E ND1 1 
ATOM   11958 C CD2 . HIS E 1 113 ? 64.960  19.627  128.842 1.00 88.87  ? 132 HIS E CD2 1 
ATOM   11959 C CE1 . HIS E 1 113 ? 63.503  20.425  127.415 1.00 84.97  ? 132 HIS E CE1 1 
ATOM   11960 N NE2 . HIS E 1 113 ? 63.639  19.925  128.632 1.00 89.13  ? 132 HIS E NE2 1 
ATOM   11961 N N   . PRO E 1 114 ? 69.951  22.116  127.010 1.00 87.44  ? 133 PRO E N   1 
ATOM   11962 C CA  . PRO E 1 114 ? 71.403  22.067  126.786 1.00 86.52  ? 133 PRO E CA  1 
ATOM   11963 C C   . PRO E 1 114 ? 72.131  21.228  127.820 1.00 87.69  ? 133 PRO E C   1 
ATOM   11964 O O   . PRO E 1 114 ? 73.270  20.825  127.566 1.00 85.91  ? 133 PRO E O   1 
ATOM   11965 C CB  . PRO E 1 114 ? 71.813  23.546  126.849 1.00 92.22  ? 133 PRO E CB  1 
ATOM   11966 C CG  . PRO E 1 114 ? 70.761  24.202  127.721 1.00 97.37  ? 133 PRO E CG  1 
ATOM   11967 C CD  . PRO E 1 114 ? 69.481  23.464  127.400 1.00 93.15  ? 133 PRO E CD  1 
ATOM   11968 N N   . GLN E 1 115 ? 71.491  20.927  128.960 1.00 91.60  ? 134 GLN E N   1 
ATOM   11969 C CA  . GLN E 1 115 ? 72.042  19.985  129.927 1.00 93.25  ? 134 GLN E CA  1 
ATOM   11970 C C   . GLN E 1 115 ? 72.281  18.600  129.332 1.00 87.19  ? 134 GLN E C   1 
ATOM   11971 O O   . GLN E 1 115 ? 73.132  17.863  129.844 1.00 87.49  ? 134 GLN E O   1 
ATOM   11972 C CB  . GLN E 1 115 ? 71.098  19.874  131.129 1.00 99.13  ? 134 GLN E CB  1 
ATOM   11973 N N   . TRP E 1 116 ? 71.567  18.237  128.258 1.00 85.89  ? 135 TRP E N   1 
ATOM   11974 C CA  . TRP E 1 116 ? 71.597  16.878  127.738 1.00 82.01  ? 135 TRP E CA  1 
ATOM   11975 C C   . TRP E 1 116 ? 72.526  16.670  126.550 1.00 79.46  ? 135 TRP E C   1 
ATOM   11976 O O   . TRP E 1 116 ? 72.891  15.527  126.271 1.00 76.75  ? 135 TRP E O   1 
ATOM   11977 C CB  . TRP E 1 116 ? 70.230  16.419  127.218 1.00 79.30  ? 135 TRP E CB  1 
ATOM   11978 C CG  . TRP E 1 116 ? 69.023  16.792  127.965 1.00 81.17  ? 135 TRP E CG  1 
ATOM   11979 C CD1 . TRP E 1 116 ? 68.933  17.473  129.137 1.00 84.78  ? 135 TRP E CD1 1 
ATOM   11980 C CD2 . TRP E 1 116 ? 67.692  16.469  127.579 1.00 79.69  ? 135 TRP E CD2 1 
ATOM   11981 N NE1 . TRP E 1 116 ? 67.613  17.589  129.508 1.00 87.71  ? 135 TRP E NE1 1 
ATOM   11982 C CE2 . TRP E 1 116 ? 66.836  16.961  128.564 1.00 83.24  ? 135 TRP E CE2 1 
ATOM   11983 C CE3 . TRP E 1 116 ? 67.141  15.791  126.495 1.00 76.61  ? 135 TRP E CE3 1 
ATOM   11984 C CZ2 . TRP E 1 116 ? 65.454  16.814  128.481 1.00 84.10  ? 135 TRP E CZ2 1 
ATOM   11985 C CZ3 . TRP E 1 116 ? 65.779  15.654  126.425 1.00 76.30  ? 135 TRP E CZ3 1 
ATOM   11986 C CH2 . TRP E 1 116 ? 64.950  16.178  127.406 1.00 79.16  ? 135 TRP E CH2 1 
ATOM   11987 N N   . TRP E 1 117 ? 72.849  17.723  125.806 1.00 81.39  ? 136 TRP E N   1 
ATOM   11988 C CA  . TRP E 1 117 ? 73.511  17.560  124.520 1.00 78.61  ? 136 TRP E CA  1 
ATOM   11989 C C   . TRP E 1 117 ? 74.758  16.699  124.675 1.00 78.15  ? 136 TRP E C   1 
ATOM   11990 O O   . TRP E 1 117 ? 75.543  16.878  125.612 1.00 81.06  ? 136 TRP E O   1 
ATOM   11991 C CB  . TRP E 1 117 ? 73.857  18.935  123.932 1.00 80.34  ? 136 TRP E CB  1 
ATOM   11992 C CG  . TRP E 1 117 ? 72.655  19.883  123.799 1.00 81.31  ? 136 TRP E CG  1 
ATOM   11993 C CD1 . TRP E 1 117 ? 71.344  19.608  124.099 1.00 80.70  ? 136 TRP E CD1 1 
ATOM   11994 C CD2 . TRP E 1 117 ? 72.668  21.234  123.285 1.00 83.24  ? 136 TRP E CD2 1 
ATOM   11995 N NE1 . TRP E 1 117 ? 70.556  20.710  123.837 1.00 82.32  ? 136 TRP E NE1 1 
ATOM   11996 C CE2 . TRP E 1 117 ? 71.342  21.719  123.339 1.00 83.75  ? 136 TRP E CE2 1 
ATOM   11997 C CE3 . TRP E 1 117 ? 73.672  22.080  122.799 1.00 84.63  ? 136 TRP E CE3 1 
ATOM   11998 C CZ2 . TRP E 1 117 ? 71.004  23.007  122.938 1.00 85.79  ? 136 TRP E CZ2 1 
ATOM   11999 C CZ3 . TRP E 1 117 ? 73.326  23.360  122.394 1.00 86.59  ? 136 TRP E CZ3 1 
ATOM   12000 C CH2 . TRP E 1 117 ? 72.008  23.805  122.462 1.00 87.10  ? 136 TRP E CH2 1 
ATOM   12001 N N   . LEU E 1 118 ? 74.905  15.728  123.770 1.00 77.67  ? 137 LEU E N   1 
ATOM   12002 C CA  . LEU E 1 118 ? 76.054  14.828  123.805 1.00 77.24  ? 137 LEU E CA  1 
ATOM   12003 C C   . LEU E 1 118 ? 77.316  15.635  123.527 1.00 78.93  ? 137 LEU E C   1 
ATOM   12004 O O   . LEU E 1 118 ? 77.385  16.354  122.528 1.00 78.50  ? 137 LEU E O   1 
ATOM   12005 C CB  . LEU E 1 118 ? 75.902  13.696  122.783 1.00 73.12  ? 137 LEU E CB  1 
ATOM   12006 N N   . ARG E 1 119 ? 78.306  15.538  124.421 1.00 77.61  ? 138 ARG E N   1 
ATOM   12007 C CA  . ARG E 1 119 ? 79.603  16.171  124.233 1.00 79.34  ? 138 ARG E CA  1 
ATOM   12008 C C   . ARG E 1 119 ? 80.710  15.116  124.126 1.00 78.08  ? 138 ARG E C   1 
ATOM   12009 O O   . ARG E 1 119 ? 80.663  14.057  124.768 1.00 77.34  ? 138 ARG E O   1 
ATOM   12010 C CB  . ARG E 1 119 ? 79.888  17.154  125.374 1.00 83.95  ? 138 ARG E CB  1 
ATOM   12011 N N   . THR E 1 120 ? 81.708  15.418  123.292 1.00 77.35  ? 139 THR E N   1 
ATOM   12012 C CA  . THR E 1 120 ? 82.847  14.542  123.085 1.00 76.94  ? 139 THR E CA  1 
ATOM   12013 C C   . THR E 1 120 ? 83.949  14.785  124.119 1.00 80.67  ? 139 THR E C   1 
ATOM   12014 O O   . THR E 1 120 ? 83.877  15.684  124.959 1.00 84.01  ? 139 THR E O   1 
ATOM   12015 C CB  . THR E 1 120 ? 83.442  14.749  121.689 1.00 75.69  ? 139 THR E CB  1 
ATOM   12016 O OG1 . THR E 1 120 ? 84.148  16.009  121.664 1.00 79.07  ? 139 THR E OG1 1 
ATOM   12017 C CG2 . THR E 1 120 ? 82.347  14.743  120.646 1.00 72.44  ? 139 THR E CG2 1 
ATOM   12018 N N   . THR E 1 121 ? 85.017  13.991  123.998 1.00 75.46  ? 140 THR E N   1 
ATOM   12019 C CA  . THR E 1 121 ? 86.151  14.070  124.920 1.00 78.76  ? 140 THR E CA  1 
ATOM   12020 C C   . THR E 1 121 ? 86.801  15.455  124.944 1.00 82.43  ? 140 THR E C   1 
ATOM   12021 O O   . THR E 1 121 ? 87.451  15.827  125.931 1.00 86.20  ? 140 THR E O   1 
ATOM   12022 C CB  . THR E 1 121 ? 87.181  13.008  124.520 1.00 77.14  ? 140 THR E CB  1 
ATOM   12023 O OG1 . THR E 1 121 ? 87.533  13.188  123.136 1.00 75.61  ? 140 THR E OG1 1 
ATOM   12024 C CG2 . THR E 1 121 ? 86.591  11.616  124.722 1.00 74.17  ? 140 THR E CG2 1 
ATOM   12025 N N   . THR E 1 122 ? 86.669  16.224  123.859 1.00 77.70  ? 141 THR E N   1 
ATOM   12026 C CA  . THR E 1 122 ? 87.207  17.578  123.822 1.00 84.14  ? 141 THR E CA  1 
ATOM   12027 C C   . THR E 1 122 ? 86.349  18.572  124.592 1.00 88.05  ? 141 THR E C   1 
ATOM   12028 O O   . THR E 1 122 ? 86.824  19.673  124.906 1.00 94.32  ? 141 THR E O   1 
ATOM   12029 C CB  . THR E 1 122 ? 87.311  18.079  122.377 1.00 83.57  ? 141 THR E CB  1 
ATOM   12030 O OG1 . THR E 1 122 ? 86.001  18.425  121.892 1.00 81.15  ? 141 THR E OG1 1 
ATOM   12031 C CG2 . THR E 1 122 ? 87.904  17.032  121.475 1.00 79.15  ? 141 THR E CG2 1 
ATOM   12032 N N   . GLY E 1 123 ? 85.099  18.206  124.880 1.00 96.22  ? 142 GLY E N   1 
ATOM   12033 C CA  . GLY E 1 123 ? 84.090  19.135  125.315 1.00 98.32  ? 142 GLY E CA  1 
ATOM   12034 C C   . GLY E 1 123 ? 83.230  19.699  124.205 1.00 95.41  ? 142 GLY E C   1 
ATOM   12035 O O   . GLY E 1 123 ? 82.223  20.349  124.497 1.00 96.42  ? 142 GLY E O   1 
ATOM   12036 N N   . GLU E 1 124 ? 83.592  19.483  122.945 1.00 91.83  ? 143 GLU E N   1 
ATOM   12037 C CA  . GLU E 1 124 ? 82.791  19.988  121.839 1.00 88.73  ? 143 GLU E CA  1 
ATOM   12038 C C   . GLU E 1 124 ? 81.469  19.240  121.770 1.00 86.04  ? 143 GLU E C   1 
ATOM   12039 O O   . GLU E 1 124 ? 81.422  18.018  121.924 1.00 84.67  ? 143 GLU E O   1 
ATOM   12040 C CB  . GLU E 1 124 ? 83.545  19.828  120.521 1.00 85.70  ? 143 GLU E CB  1 
ATOM   12041 N N   . LEU E 1 125 ? 80.382  19.976  121.554 1.00 85.09  ? 144 LEU E N   1 
ATOM   12042 C CA  . LEU E 1 125 ? 79.105  19.329  121.279 1.00 82.38  ? 144 LEU E CA  1 
ATOM   12043 C C   . LEU E 1 125 ? 79.311  18.344  120.136 1.00 78.11  ? 144 LEU E C   1 
ATOM   12044 O O   . LEU E 1 125 ? 79.946  18.673  119.129 1.00 76.55  ? 144 LEU E O   1 
ATOM   12045 C CB  . LEU E 1 125 ? 78.022  20.354  120.929 1.00 82.13  ? 144 LEU E CB  1 
ATOM   12046 N N   . ASP E 1 126 ? 78.806  17.125  120.320 1.00 79.85  ? 145 ASP E N   1 
ATOM   12047 C CA  . ASP E 1 126 ? 78.840  16.093  119.280 1.00 77.24  ? 145 ASP E CA  1 
ATOM   12048 C C   . ASP E 1 126 ? 77.749  16.376  118.253 1.00 75.15  ? 145 ASP E C   1 
ATOM   12049 O O   . ASP E 1 126 ? 76.560  16.174  118.527 1.00 75.05  ? 145 ASP E O   1 
ATOM   12050 C CB  . ASP E 1 126 ? 78.650  14.700  119.880 1.00 77.85  ? 145 ASP E CB  1 
ATOM   12051 C CG  . ASP E 1 126 ? 78.825  13.599  118.857 1.00 75.79  ? 145 ASP E CG  1 
ATOM   12052 O OD1 . ASP E 1 126 ? 78.680  13.894  117.661 1.00 73.46  ? 145 ASP E OD1 1 
ATOM   12053 O OD2 . ASP E 1 126 ? 79.115  12.445  119.235 1.00 76.35  ? 145 ASP E OD2 1 
ATOM   12054 N N   . ARG E 1 127 ? 78.151  16.830  117.070 1.00 80.33  ? 146 ARG E N   1 
ATOM   12055 C CA  . ARG E 1 127 ? 77.244  17.030  115.949 1.00 78.42  ? 146 ARG E CA  1 
ATOM   12056 C C   . ARG E 1 127 ? 77.794  16.299  114.727 1.00 76.36  ? 146 ARG E C   1 
ATOM   12057 O O   . ARG E 1 127 ? 79.015  16.216  114.540 1.00 76.84  ? 146 ARG E O   1 
ATOM   12058 C CB  . ARG E 1 127 ? 77.059  18.524  115.659 1.00 79.08  ? 146 ARG E CB  1 
ATOM   12059 N N   . LYS E 1 128 ? 76.896  15.723  113.919 1.00 82.90  ? 147 LYS E N   1 
ATOM   12060 C CA  . LYS E 1 128 ? 77.287  15.304  112.577 1.00 80.90  ? 147 LYS E CA  1 
ATOM   12061 C C   . LYS E 1 128 ? 77.564  16.551  111.733 1.00 80.75  ? 147 LYS E C   1 
ATOM   12062 O O   . LYS E 1 128 ? 77.269  17.695  112.139 1.00 82.26  ? 147 LYS E O   1 
ATOM   12063 C CB  . LYS E 1 128 ? 76.208  14.441  111.926 1.00 79.28  ? 147 LYS E CB  1 
ATOM   12064 N N   . LYS E 1 129 ? 78.165  16.347  110.559 1.00 84.49  ? 148 LYS E N   1 
ATOM   12065 C CA  . LYS E 1 129 ? 78.301  17.471  109.641 1.00 84.52  ? 148 LYS E CA  1 
ATOM   12066 C C   . LYS E 1 129 ? 76.950  18.179  109.533 1.00 84.42  ? 148 LYS E C   1 
ATOM   12067 O O   . LYS E 1 129 ? 75.888  17.571  109.714 1.00 84.09  ? 148 LYS E O   1 
ATOM   12068 C CB  . LYS E 1 129 ? 78.782  17.003  108.274 1.00 82.66  ? 148 LYS E CB  1 
ATOM   12069 N N   . GLY E 1 130 ? 76.982  19.475  109.287 1.00 84.90  ? 149 GLY E N   1 
ATOM   12070 C CA  . GLY E 1 130 ? 75.754  20.209  109.114 1.00 84.74  ? 149 GLY E CA  1 
ATOM   12071 C C   . GLY E 1 130 ? 75.129  20.743  110.383 1.00 87.13  ? 149 GLY E C   1 
ATOM   12072 O O   . GLY E 1 130 ? 74.029  21.328  110.318 1.00 87.00  ? 149 GLY E O   1 
ATOM   12073 N N   . GLN E 1 131 ? 75.801  20.598  111.526 1.00 82.48  ? 150 GLN E N   1 
ATOM   12074 C CA  . GLN E 1 131 ? 75.260  20.984  112.825 1.00 84.71  ? 150 GLN E CA  1 
ATOM   12075 C C   . GLN E 1 131 ? 74.050  20.130  113.249 1.00 84.28  ? 150 GLN E C   1 
ATOM   12076 O O   . GLN E 1 131 ? 73.232  20.580  114.061 1.00 85.51  ? 150 GLN E O   1 
ATOM   12077 C CB  . GLN E 1 131 ? 74.889  22.491  112.862 1.00 85.97  ? 150 GLN E CB  1 
ATOM   12078 N N   . LEU E 1 132 ? 73.916  18.901  112.716 1.00 79.00  ? 151 LEU E N   1 
ATOM   12079 C CA  . LEU E 1 132 ? 72.968  17.929  113.271 1.00 78.21  ? 151 LEU E CA  1 
ATOM   12080 C C   . LEU E 1 132 ? 73.601  17.253  114.496 1.00 79.44  ? 151 LEU E C   1 
ATOM   12081 O O   . LEU E 1 132 ? 74.711  16.716  114.424 1.00 79.34  ? 151 LEU E O   1 
ATOM   12082 C CB  . LEU E 1 132 ? 72.541  16.885  112.234 1.00 75.84  ? 151 LEU E CB  1 
ATOM   12083 N N   . MET E 1 133 ? 72.888  17.307  115.620 1.00 73.05  ? 152 MET E N   1 
ATOM   12084 C CA  . MET E 1 133 ? 73.354  16.882  116.935 1.00 74.73  ? 152 MET E CA  1 
ATOM   12085 C C   . MET E 1 133 ? 73.058  15.409  117.156 1.00 74.17  ? 152 MET E C   1 
ATOM   12086 O O   . MET E 1 133 ? 72.081  14.882  116.622 1.00 72.99  ? 152 MET E O   1 
ATOM   12087 C CB  . MET E 1 133 ? 72.644  17.700  118.023 1.00 77.44  ? 152 MET E CB  1 
ATOM   12088 C CG  . MET E 1 133 ? 73.073  19.140  118.097 1.00 79.28  ? 152 MET E CG  1 
ATOM   12089 S SD  . MET E 1 133 ? 72.382  19.988  119.545 1.00 81.01  ? 152 MET E SD  1 
ATOM   12090 C CE  . MET E 1 133 ? 72.839  18.819  120.832 1.00 80.51  ? 152 MET E CE  1 
ATOM   12091 N N   . ARG E 1 134 ? 73.861  14.761  118.004 1.00 71.35  ? 153 ARG E N   1 
ATOM   12092 C CA  . ARG E 1 134 ? 73.669  13.348  118.309 1.00 71.03  ? 153 ARG E CA  1 
ATOM   12093 C C   . ARG E 1 134 ? 73.343  13.138  119.777 1.00 73.77  ? 153 ARG E C   1 
ATOM   12094 O O   . ARG E 1 134 ? 73.864  13.848  120.654 1.00 76.30  ? 153 ARG E O   1 
ATOM   12095 C CB  . ARG E 1 134 ? 74.903  12.542  117.914 1.00 70.37  ? 153 ARG E CB  1 
ATOM   12096 C CG  . ARG E 1 134 ? 75.308  12.776  116.450 1.00 67.77  ? 153 ARG E CG  1 
ATOM   12097 C CD  . ARG E 1 134 ? 76.152  11.643  115.870 1.00 66.45  ? 153 ARG E CD  1 
ATOM   12098 N NE  . ARG E 1 134 ? 77.384  11.449  116.620 1.00 68.28  ? 153 ARG E NE  1 
ATOM   12099 C CZ  . ARG E 1 134 ? 78.128  10.355  116.568 1.00 68.15  ? 153 ARG E CZ  1 
ATOM   12100 N NH1 . ARG E 1 134 ? 77.771  9.316   115.830 1.00 65.82  ? 153 ARG E NH1 1 
ATOM   12101 N NH2 . ARG E 1 134 ? 79.259  10.304  117.271 1.00 70.15  ? 153 ARG E NH2 1 
ATOM   12102 N N   . TYR E 1 135 ? 72.469  12.156  120.024 1.00 68.70  ? 154 TYR E N   1 
ATOM   12103 C CA  . TYR E 1 135 ? 71.837  11.961  121.322 1.00 71.07  ? 154 TYR E CA  1 
ATOM   12104 C C   . TYR E 1 135 ? 72.724  11.123  122.242 1.00 72.54  ? 154 TYR E C   1 
ATOM   12105 O O   . TYR E 1 135 ? 73.396  10.187  121.798 1.00 71.85  ? 154 TYR E O   1 
ATOM   12106 C CB  . TYR E 1 135 ? 70.483  11.256  121.177 1.00 70.03  ? 154 TYR E CB  1 
ATOM   12107 C CG  . TYR E 1 135 ? 69.366  12.005  120.465 1.00 68.81  ? 154 TYR E CG  1 
ATOM   12108 C CD1 . TYR E 1 135 ? 68.996  13.303  120.827 1.00 69.72  ? 154 TYR E CD1 1 
ATOM   12109 C CD2 . TYR E 1 135 ? 68.648  11.389  119.445 1.00 66.90  ? 154 TYR E CD2 1 
ATOM   12110 C CE1 . TYR E 1 135 ? 67.931  13.971  120.156 1.00 68.62  ? 154 TYR E CE1 1 
ATOM   12111 C CE2 . TYR E 1 135 ? 67.604  12.037  118.781 1.00 65.79  ? 154 TYR E CE2 1 
ATOM   12112 C CZ  . TYR E 1 135 ? 67.241  13.316  119.130 1.00 66.45  ? 154 TYR E CZ  1 
ATOM   12113 O OH  . TYR E 1 135 ? 66.196  13.922  118.444 1.00 65.55  ? 154 TYR E OH  1 
ATOM   12114 N N   . ASP E 1 136 ? 72.712  11.463  123.530 1.00 74.15  ? 155 ASP E N   1 
ATOM   12115 C CA  . ASP E 1 136 ? 73.349  10.640  124.555 1.00 76.62  ? 155 ASP E CA  1 
ATOM   12116 C C   . ASP E 1 136 ? 72.276  9.699   125.090 1.00 76.72  ? 155 ASP E C   1 
ATOM   12117 O O   . ASP E 1 136 ? 71.459  10.074  125.935 1.00 79.01  ? 155 ASP E O   1 
ATOM   12118 C CB  . ASP E 1 136 ? 73.955  11.486  125.670 1.00 80.90  ? 155 ASP E CB  1 
ATOM   12119 C CG  . ASP E 1 136 ? 74.649  10.637  126.745 1.00 83.62  ? 155 ASP E CG  1 
ATOM   12120 O OD1 . ASP E 1 136 ? 74.603  9.390   126.641 1.00 82.11  ? 155 ASP E OD1 1 
ATOM   12121 O OD2 . ASP E 1 136 ? 75.246  11.212  127.695 1.00 87.38  ? 155 ASP E OD2 1 
ATOM   12122 N N   . LEU E 1 137 ? 72.286  8.462   124.610 1.00 77.08  ? 156 LEU E N   1 
ATOM   12123 C CA  . LEU E 1 137 ? 71.292  7.496   125.050 1.00 76.18  ? 156 LEU E CA  1 
ATOM   12124 C C   . LEU E 1 137 ? 71.450  7.087   126.511 1.00 78.82  ? 156 LEU E C   1 
ATOM   12125 O O   . LEU E 1 137 ? 70.531  6.467   127.060 1.00 79.61  ? 156 LEU E O   1 
ATOM   12126 C CB  . LEU E 1 137 ? 71.364  6.259   124.153 1.00 74.29  ? 156 LEU E CB  1 
ATOM   12127 C CG  . LEU E 1 137 ? 71.275  6.490   122.644 1.00 73.12  ? 156 LEU E CG  1 
ATOM   12128 C CD1 . LEU E 1 137 ? 71.067  5.140   121.951 1.00 70.20  ? 156 LEU E CD1 1 
ATOM   12129 C CD2 . LEU E 1 137 ? 70.173  7.439   122.275 1.00 72.81  ? 156 LEU E CD2 1 
ATOM   12130 N N   . SER E 1 138 ? 72.565  7.420   127.156 1.00 80.70  ? 157 SER E N   1 
ATOM   12131 C CA  . SER E 1 138 ? 72.750  7.072   128.565 1.00 84.78  ? 157 SER E CA  1 
ATOM   12132 C C   . SER E 1 138 ? 72.017  8.014   129.515 1.00 87.93  ? 157 SER E C   1 
ATOM   12133 O O   . SER E 1 138 ? 71.857  7.664   130.688 1.00 91.25  ? 157 SER E O   1 
ATOM   12134 C CB  . SER E 1 138 ? 74.245  7.033   128.890 1.00 86.60  ? 157 SER E CB  1 
ATOM   12135 O OG  . SER E 1 138 ? 74.813  8.325   128.860 1.00 88.24  ? 157 SER E OG  1 
ATOM   12136 N N   . ASN E 1 139 ? 71.516  9.155   129.024 1.00 86.99  ? 158 ASN E N   1 
ATOM   12137 C CA  . ASN E 1 139 ? 70.763  10.128  129.828 1.00 89.99  ? 158 ASN E CA  1 
ATOM   12138 C C   . ASN E 1 139 ? 69.300  9.698   129.963 1.00 89.34  ? 158 ASN E C   1 
ATOM   12139 O O   . ASN E 1 139 ? 68.504  9.851   129.032 1.00 86.15  ? 158 ASN E O   1 
ATOM   12140 C CB  . ASN E 1 139 ? 70.864  11.515  129.180 1.00 89.37  ? 158 ASN E CB  1 
ATOM   12141 C CG  . ASN E 1 139 ? 70.065  12.603  129.920 1.00 92.57  ? 158 ASN E CG  1 
ATOM   12142 O OD1 . ASN E 1 139 ? 69.153  12.326  130.692 1.00 94.47  ? 158 ASN E OD1 1 
ATOM   12143 N ND2 . ASN E 1 139 ? 70.405  13.854  129.649 1.00 93.05  ? 158 ASN E ND2 1 
ATOM   12144 N N   . ALA E 1 140 ? 68.924  9.209   131.143 1.00 92.72  ? 159 ALA E N   1 
ATOM   12145 C CA  . ALA E 1 140 ? 67.553  8.760   131.344 1.00 92.47  ? 159 ALA E CA  1 
ATOM   12146 C C   . ALA E 1 140 ? 66.557  9.898   131.144 1.00 92.19  ? 159 ALA E C   1 
ATOM   12147 O O   . ALA E 1 140 ? 65.458  9.677   130.626 1.00 90.05  ? 159 ALA E O   1 
ATOM   12148 C CB  . ALA E 1 140 ? 67.412  8.142   132.734 1.00 96.48  ? 159 ALA E CB  1 
ATOM   12149 N N   . GLU E 1 141 ? 66.912  11.122  131.552 1.00 94.43  ? 160 GLU E N   1 
ATOM   12150 C CA  . GLU E 1 141 ? 66.002  12.253  131.363 1.00 94.23  ? 160 GLU E CA  1 
ATOM   12151 C C   . GLU E 1 141 ? 65.654  12.412  129.892 1.00 89.70  ? 160 GLU E C   1 
ATOM   12152 O O   . GLU E 1 141 ? 64.506  12.709  129.531 1.00 88.12  ? 160 GLU E O   1 
ATOM   12153 C CB  . GLU E 1 141 ? 66.626  13.537  131.905 1.00 97.55  ? 160 GLU E CB  1 
ATOM   12154 N N   . PHE E 1 142 ? 66.636  12.181  129.027 1.00 87.71  ? 161 PHE E N   1 
ATOM   12155 C CA  . PHE E 1 142 ? 66.402  12.235  127.595 1.00 83.38  ? 161 PHE E CA  1 
ATOM   12156 C C   . PHE E 1 142 ? 65.582  11.044  127.104 1.00 80.65  ? 161 PHE E C   1 
ATOM   12157 O O   . PHE E 1 142 ? 64.673  11.202  126.276 1.00 78.05  ? 161 PHE E O   1 
ATOM   12158 C CB  . PHE E 1 142 ? 67.732  12.257  126.870 1.00 81.94  ? 161 PHE E CB  1 
ATOM   12159 C CG  . PHE E 1 142 ? 67.677  11.638  125.512 1.00 77.52  ? 161 PHE E CG  1 
ATOM   12160 C CD1 . PHE E 1 142 ? 67.204  12.367  124.438 1.00 75.08  ? 161 PHE E CD1 1 
ATOM   12161 C CD2 . PHE E 1 142 ? 68.098  10.330  125.309 1.00 75.95  ? 161 PHE E CD2 1 
ATOM   12162 C CE1 . PHE E 1 142 ? 67.157  11.809  123.182 1.00 71.21  ? 161 PHE E CE1 1 
ATOM   12163 C CE2 . PHE E 1 142 ? 68.066  9.768   124.059 1.00 72.04  ? 161 PHE E CE2 1 
ATOM   12164 C CZ  . PHE E 1 142 ? 67.586  10.499  122.989 1.00 69.72  ? 161 PHE E CZ  1 
ATOM   12165 N N   . ARG E 1 143 ? 65.934  9.835   127.540 1.00 81.21  ? 162 ARG E N   1 
ATOM   12166 C CA  . ARG E 1 143 ? 65.214  8.659   127.073 1.00 78.70  ? 162 ARG E CA  1 
ATOM   12167 C C   . ARG E 1 143 ? 63.728  8.813   127.348 1.00 79.27  ? 162 ARG E C   1 
ATOM   12168 O O   . ARG E 1 143 ? 62.892  8.598   126.459 1.00 76.50  ? 162 ARG E O   1 
ATOM   12169 C CB  . ARG E 1 143 ? 65.765  7.399   127.739 1.00 79.74  ? 162 ARG E CB  1 
ATOM   12170 C CG  . ARG E 1 143 ? 67.192  7.007   127.322 1.00 78.55  ? 162 ARG E CG  1 
ATOM   12171 C CD  . ARG E 1 143 ? 67.485  5.521   127.626 1.00 78.59  ? 162 ARG E CD  1 
ATOM   12172 N NE  . ARG E 1 143 ? 67.164  5.162   129.007 1.00 82.36  ? 162 ARG E NE  1 
ATOM   12173 C CZ  . ARG E 1 143 ? 68.014  5.227   130.030 1.00 85.68  ? 162 ARG E CZ  1 
ATOM   12174 N NH1 . ARG E 1 143 ? 69.276  5.588   129.860 1.00 85.83  ? 162 ARG E NH1 1 
ATOM   12175 N NH2 . ARG E 1 143 ? 67.585  4.922   131.252 1.00 89.09  ? 162 ARG E NH2 1 
ATOM   12176 N N   . ASN E 1 144 ? 63.380  9.205   128.578 1.00 82.94  ? 163 ASN E N   1 
ATOM   12177 C CA  . ASN E 1 144 ? 61.978  9.427   128.919 1.00 83.72  ? 163 ASN E CA  1 
ATOM   12178 C C   . ASN E 1 144 ? 61.313  10.354  127.907 1.00 81.40  ? 163 ASN E C   1 
ATOM   12179 O O   . ASN E 1 144 ? 60.205  10.092  127.431 1.00 79.83  ? 163 ASN E O   1 
ATOM   12180 C CB  . ASN E 1 144 ? 61.872  9.997   130.329 1.00 88.28  ? 163 ASN E CB  1 
ATOM   12181 C CG  . ASN E 1 144 ? 60.428  10.137  130.795 1.00 89.43  ? 163 ASN E CG  1 
ATOM   12182 O OD1 . ASN E 1 144 ? 59.745  9.149   131.052 1.00 89.00  ? 163 ASN E OD1 1 
ATOM   12183 N ND2 . ASN E 1 144 ? 59.968  11.382  130.923 1.00 90.84  ? 163 ASN E ND2 1 
ATOM   12184 N N   . TRP E 1 145 ? 61.998  11.445  127.558 1.00 81.35  ? 164 TRP E N   1 
ATOM   12185 C CA  . TRP E 1 145 ? 61.476  12.405  126.586 1.00 79.27  ? 164 TRP E CA  1 
ATOM   12186 C C   . TRP E 1 145 ? 61.357  11.783  125.193 1.00 74.96  ? 164 TRP E C   1 
ATOM   12187 O O   . TRP E 1 145 ? 60.338  11.926  124.501 1.00 73.11  ? 164 TRP E O   1 
ATOM   12188 C CB  . TRP E 1 145 ? 62.405  13.628  126.561 1.00 80.49  ? 164 TRP E CB  1 
ATOM   12189 C CG  . TRP E 1 145 ? 62.139  14.569  125.459 1.00 78.28  ? 164 TRP E CG  1 
ATOM   12190 C CD1 . TRP E 1 145 ? 61.173  15.527  125.424 1.00 78.96  ? 164 TRP E CD1 1 
ATOM   12191 C CD2 . TRP E 1 145 ? 62.838  14.657  124.216 1.00 75.18  ? 164 TRP E CD2 1 
ATOM   12192 N NE1 . TRP E 1 145 ? 61.223  16.208  124.233 1.00 76.51  ? 164 TRP E NE1 1 
ATOM   12193 C CE2 . TRP E 1 145 ? 62.234  15.691  123.470 1.00 74.17  ? 164 TRP E CE2 1 
ATOM   12194 C CE3 . TRP E 1 145 ? 63.910  13.961  123.656 1.00 73.24  ? 164 TRP E CE3 1 
ATOM   12195 C CZ2 . TRP E 1 145 ? 62.667  16.048  122.196 1.00 71.38  ? 164 TRP E CZ2 1 
ATOM   12196 C CZ3 . TRP E 1 145 ? 64.339  14.308  122.381 1.00 70.40  ? 164 TRP E CZ3 1 
ATOM   12197 C CH2 . TRP E 1 145 ? 63.722  15.344  121.669 1.00 69.53  ? 164 TRP E CH2 1 
ATOM   12198 N N   . TRP E 1 146 ? 62.405  11.101  124.759 1.00 76.63  ? 165 TRP E N   1 
ATOM   12199 C CA  . TRP E 1 146 ? 62.410  10.552  123.416 1.00 72.68  ? 165 TRP E CA  1 
ATOM   12200 C C   . TRP E 1 146 ? 61.283  9.554   123.232 1.00 71.42  ? 165 TRP E C   1 
ATOM   12201 O O   . TRP E 1 146 ? 60.616  9.532   122.188 1.00 68.84  ? 165 TRP E O   1 
ATOM   12202 C CB  . TRP E 1 146 ? 63.748  9.892   123.163 1.00 72.26  ? 165 TRP E CB  1 
ATOM   12203 C CG  . TRP E 1 146 ? 63.915  9.455   121.796 1.00 69.84  ? 165 TRP E CG  1 
ATOM   12204 C CD1 . TRP E 1 146 ? 64.522  10.139  120.794 1.00 69.44  ? 165 TRP E CD1 1 
ATOM   12205 C CD2 . TRP E 1 146 ? 63.483  8.214   121.243 1.00 67.24  ? 165 TRP E CD2 1 
ATOM   12206 N NE1 . TRP E 1 146 ? 64.501  9.392   119.640 1.00 66.97  ? 165 TRP E NE1 1 
ATOM   12207 C CE2 . TRP E 1 146 ? 63.870  8.204   119.893 1.00 65.27  ? 165 TRP E CE2 1 
ATOM   12208 C CE3 . TRP E 1 146 ? 62.816  7.105   121.762 1.00 66.58  ? 165 TRP E CE3 1 
ATOM   12209 C CZ2 . TRP E 1 146 ? 63.607  7.139   119.057 1.00 62.77  ? 165 TRP E CZ2 1 
ATOM   12210 C CZ3 . TRP E 1 146 ? 62.567  6.050   120.939 1.00 63.76  ? 165 TRP E CZ3 1 
ATOM   12211 C CH2 . TRP E 1 146 ? 62.954  6.073   119.598 1.00 61.88  ? 165 TRP E CH2 1 
ATOM   12212 N N   . THR E 1 147 ? 61.066  8.709   124.231 1.00 71.44  ? 166 THR E N   1 
ATOM   12213 C CA  . THR E 1 147 ? 59.964  7.765   124.155 1.00 70.62  ? 166 THR E CA  1 
ATOM   12214 C C   . THR E 1 147 ? 58.634  8.500   124.200 1.00 71.37  ? 166 THR E C   1 
ATOM   12215 O O   . THR E 1 147 ? 57.681  8.121   123.520 1.00 69.62  ? 166 THR E O   1 
ATOM   12216 C CB  . THR E 1 147 ? 60.081  6.765   125.290 1.00 72.93  ? 166 THR E CB  1 
ATOM   12217 O OG1 . THR E 1 147 ? 60.290  7.482   126.507 1.00 76.68  ? 166 THR E OG1 1 
ATOM   12218 C CG2 . THR E 1 147 ? 61.270  5.861   125.040 1.00 71.97  ? 166 THR E CG2 1 
ATOM   12219 N N   . ASN E 1 148 ? 58.550  9.573   124.988 1.00 72.61  ? 167 ASN E N   1 
ATOM   12220 C CA  . ASN E 1 148 ? 57.300  10.327  125.054 1.00 73.23  ? 167 ASN E CA  1 
ATOM   12221 C C   . ASN E 1 148 ? 56.908  10.843  123.678 1.00 70.06  ? 167 ASN E C   1 
ATOM   12222 O O   . ASN E 1 148 ? 55.733  10.795  123.298 1.00 69.16  ? 167 ASN E O   1 
ATOM   12223 C CB  . ASN E 1 148 ? 57.434  11.484  126.045 1.00 76.57  ? 167 ASN E CB  1 
ATOM   12224 C CG  . ASN E 1 148 ? 57.335  11.036  127.497 1.00 80.24  ? 167 ASN E CG  1 
ATOM   12225 O OD1 . ASN E 1 148 ? 56.898  9.929   127.800 1.00 80.38  ? 167 ASN E OD1 1 
ATOM   12226 N ND2 . ASN E 1 148 ? 57.769  11.903  128.402 1.00 83.40  ? 167 ASN E ND2 1 
ATOM   12227 N N   . VAL E 1 149 ? 57.877  11.356  122.924 1.00 71.75  ? 168 VAL E N   1 
ATOM   12228 C CA  . VAL E 1 149 ? 57.585  11.807  121.573 1.00 68.69  ? 168 VAL E CA  1 
ATOM   12229 C C   . VAL E 1 149 ? 56.982  10.660  120.777 1.00 65.84  ? 168 VAL E C   1 
ATOM   12230 O O   . VAL E 1 149 ? 55.976  10.825  120.080 1.00 64.55  ? 168 VAL E O   1 
ATOM   12231 C CB  . VAL E 1 149 ? 58.860  12.360  120.902 1.00 67.27  ? 168 VAL E CB  1 
ATOM   12232 C CG1 . VAL E 1 149 ? 58.584  12.713  119.426 1.00 65.05  ? 168 VAL E CG1 1 
ATOM   12233 C CG2 . VAL E 1 149 ? 59.394  13.572  121.660 1.00 70.28  ? 168 VAL E CG2 1 
ATOM   12234 N N   . ALA E 1 150 ? 57.588  9.475   120.886 1.00 68.18  ? 169 ALA E N   1 
ATOM   12235 C CA  . ALA E 1 150 ? 57.101  8.303   120.170 1.00 65.92  ? 169 ALA E CA  1 
ATOM   12236 C C   . ALA E 1 150 ? 55.684  7.962   120.592 1.00 66.98  ? 169 ALA E C   1 
ATOM   12237 O O   . ALA E 1 150 ? 54.778  7.886   119.765 1.00 65.18  ? 169 ALA E O   1 
ATOM   12238 C CB  . ALA E 1 150 ? 58.048  7.130   120.408 1.00 66.11  ? 169 ALA E CB  1 
ATOM   12239 N N   . ALA E 1 151 ? 55.459  7.786   121.881 1.00 66.68  ? 170 ALA E N   1 
ATOM   12240 C CA  . ALA E 1 151 ? 54.106  7.495   122.340 1.00 67.83  ? 170 ALA E CA  1 
ATOM   12241 C C   . ALA E 1 151 ? 53.088  8.495   121.791 1.00 67.26  ? 170 ALA E C   1 
ATOM   12242 O O   . ALA E 1 151 ? 51.995  8.099   121.366 1.00 66.60  ? 170 ALA E O   1 
ATOM   12243 C CB  . ALA E 1 151 ? 54.074  7.460   123.875 1.00 71.52  ? 170 ALA E CB  1 
ATOM   12244 N N   . LYS E 1 152 ? 53.418  9.794   121.775 1.00 69.03  ? 171 LYS E N   1 
ATOM   12245 C CA  . LYS E 1 152 ? 52.426  10.750  121.295 1.00 68.62  ? 171 LYS E CA  1 
ATOM   12246 C C   . LYS E 1 152 ? 51.998  10.402  119.878 1.00 65.05  ? 171 LYS E C   1 
ATOM   12247 O O   . LYS E 1 152 ? 50.822  10.533  119.524 1.00 65.02  ? 171 LYS E O   1 
ATOM   12248 C CB  . LYS E 1 152 ? 52.938  12.190  121.319 1.00 70.02  ? 171 LYS E CB  1 
ATOM   12249 C CG  . LYS E 1 152 ? 51.976  13.138  120.538 1.00 70.82  ? 171 LYS E CG  1 
ATOM   12250 C CD  . LYS E 1 152 ? 51.661  14.463  121.258 1.00 75.03  ? 171 LYS E CD  1 
ATOM   12251 C CE  . LYS E 1 152 ? 52.645  15.563  120.837 1.00 75.86  ? 171 LYS E CE  1 
ATOM   12252 N NZ  . LYS E 1 152 ? 52.575  16.774  121.708 1.00 79.88  ? 171 LYS E NZ  1 
ATOM   12253 N N   . ALA E 1 153 ? 52.953  9.976   119.051 1.00 65.94  ? 172 ALA E N   1 
ATOM   12254 C CA  . ALA E 1 153 ? 52.673  9.728   117.642 1.00 63.06  ? 172 ALA E CA  1 
ATOM   12255 C C   . ALA E 1 153 ? 51.787  8.503   117.455 1.00 62.31  ? 172 ALA E C   1 
ATOM   12256 O O   . ALA E 1 153 ? 50.887  8.502   116.599 1.00 61.25  ? 172 ALA E O   1 
ATOM   12257 C CB  . ALA E 1 153 ? 53.988  9.557   116.878 1.00 61.85  ? 172 ALA E CB  1 
ATOM   12258 N N   . VAL E 1 154 ? 52.012  7.462   118.256 1.00 61.66  ? 173 VAL E N   1 
ATOM   12259 C CA  . VAL E 1 154 ? 51.354  6.179   118.016 1.00 61.38  ? 173 VAL E CA  1 
ATOM   12260 C C   . VAL E 1 154 ? 50.213  5.955   118.999 1.00 63.95  ? 173 VAL E C   1 
ATOM   12261 O O   . VAL E 1 154 ? 49.191  5.361   118.651 1.00 63.69  ? 173 VAL E O   1 
ATOM   12262 C CB  . VAL E 1 154 ? 52.368  5.027   118.068 1.00 61.67  ? 173 VAL E CB  1 
ATOM   12263 C CG1 . VAL E 1 154 ? 53.671  5.408   117.340 1.00 59.35  ? 173 VAL E CG1 1 
ATOM   12264 C CG2 . VAL E 1 154 ? 52.660  4.650   119.495 1.00 65.19  ? 173 VAL E CG2 1 
ATOM   12265 N N   . VAL E 1 155 ? 50.374  6.413   120.242 1.00 63.63  ? 174 VAL E N   1 
ATOM   12266 C CA  . VAL E 1 155 ? 49.302  6.207   121.221 1.00 66.13  ? 174 VAL E CA  1 
ATOM   12267 C C   . VAL E 1 155 ? 48.188  7.236   121.028 1.00 66.48  ? 174 VAL E C   1 
ATOM   12268 O O   . VAL E 1 155 ? 47.040  6.882   120.731 1.00 66.43  ? 174 VAL E O   1 
ATOM   12269 C CB  . VAL E 1 155 ? 49.853  6.235   122.657 1.00 69.21  ? 174 VAL E CB  1 
ATOM   12270 C CG1 . VAL E 1 155 ? 48.788  6.707   123.598 1.00 71.99  ? 174 VAL E CG1 1 
ATOM   12271 C CG2 . VAL E 1 155 ? 50.326  4.861   123.075 1.00 69.70  ? 174 VAL E CG2 1 
ATOM   12272 N N   . ASP E 1 156 ? 48.516  8.527   121.201 1.00 67.44  ? 175 ASP E N   1 
ATOM   12273 C CA  . ASP E 1 156 ? 47.531  9.591   121.017 1.00 67.87  ? 175 ASP E CA  1 
ATOM   12274 C C   . ASP E 1 156 ? 47.159  9.755   119.556 1.00 65.29  ? 175 ASP E C   1 
ATOM   12275 O O   . ASP E 1 156 ? 46.014  10.089  119.235 1.00 65.58  ? 175 ASP E O   1 
ATOM   12276 C CB  . ASP E 1 156 ? 48.084  10.898  121.566 1.00 69.69  ? 175 ASP E CB  1 
ATOM   12277 C CG  . ASP E 1 156 ? 48.489  10.769  123.009 1.00 74.40  ? 175 ASP E CG  1 
ATOM   12278 O OD1 . ASP E 1 156 ? 47.826  9.963   123.712 1.00 76.70  ? 175 ASP E OD1 1 
ATOM   12279 O OD2 . ASP E 1 156 ? 49.457  11.446  123.438 1.00 76.34  ? 175 ASP E OD2 1 
ATOM   12280 N N   . GLY E 1 157 ? 48.104  9.498   118.659 1.00 65.74  ? 176 GLY E N   1 
ATOM   12281 C CA  . GLY E 1 157 ? 47.912  9.722   117.250 1.00 63.10  ? 176 GLY E CA  1 
ATOM   12282 C C   . GLY E 1 157 ? 47.504  8.456   116.518 1.00 61.55  ? 176 GLY E C   1 
ATOM   12283 O O   . GLY E 1 157 ? 47.244  7.399   117.099 1.00 62.85  ? 176 GLY E O   1 
ATOM   12284 N N   . THR E 1 158 ? 47.469  8.580   115.210 1.00 58.82  ? 177 THR E N   1 
ATOM   12285 C CA  . THR E 1 158 ? 46.846  7.616   114.326 1.00 58.57  ? 177 THR E CA  1 
ATOM   12286 C C   . THR E 1 158 ? 47.833  6.577   113.831 1.00 57.19  ? 177 THR E C   1 
ATOM   12287 O O   . THR E 1 158 ? 47.446  5.669   113.086 1.00 57.32  ? 177 THR E O   1 
ATOM   12288 C CB  . THR E 1 158 ? 46.196  8.408   113.188 1.00 58.69  ? 177 THR E CB  1 
ATOM   12289 O OG1 . THR E 1 158 ? 44.927  8.905   113.644 1.00 60.58  ? 177 THR E OG1 1 
ATOM   12290 C CG2 . THR E 1 158 ? 45.971  7.577   111.946 1.00 58.26  ? 177 THR E CG2 1 
ATOM   12291 N N   . CYS E 1 159 ? 49.081  6.655   114.259 1.00 57.37  ? 178 CYS E N   1 
ATOM   12292 C CA  . CYS E 1 159 ? 50.062  5.688   113.823 1.00 55.78  ? 178 CYS E CA  1 
ATOM   12293 C C   . CYS E 1 159 ? 49.967  4.394   114.630 1.00 56.20  ? 178 CYS E C   1 
ATOM   12294 O O   . CYS E 1 159 ? 49.462  4.356   115.759 1.00 57.74  ? 178 CYS E O   1 
ATOM   12295 C CB  . CYS E 1 159 ? 51.458  6.274   113.935 1.00 55.41  ? 178 CYS E CB  1 
ATOM   12296 S SG  . CYS E 1 159 ? 51.789  7.493   112.683 1.00 54.76  ? 178 CYS E SG  1 
ATOM   12297 N N   . ASP E 1 160 ? 50.464  3.319   114.012 1.00 53.10  ? 179 ASP E N   1 
ATOM   12298 C CA  . ASP E 1 160 ? 50.426  1.981   114.577 1.00 53.03  ? 179 ASP E CA  1 
ATOM   12299 C C   . ASP E 1 160 ? 51.756  1.548   115.165 1.00 52.28  ? 179 ASP E C   1 
ATOM   12300 O O   . ASP E 1 160 ? 51.828  0.459   115.746 1.00 52.57  ? 179 ASP E O   1 
ATOM   12301 C CB  . ASP E 1 160 ? 50.019  0.972   113.501 1.00 52.99  ? 179 ASP E CB  1 
ATOM   12302 C CG  . ASP E 1 160 ? 48.769  1.367   112.814 1.00 54.12  ? 179 ASP E CG  1 
ATOM   12303 O OD1 . ASP E 1 160 ? 47.712  1.263   113.468 1.00 56.07  ? 179 ASP E OD1 1 
ATOM   12304 O OD2 . ASP E 1 160 ? 48.841  1.817   111.649 1.00 53.83  ? 179 ASP E OD2 1 
ATOM   12305 N N   . GLY E 1 161 ? 52.799  2.350   115.009 1.00 51.76  ? 180 GLY E N   1 
ATOM   12306 C CA  . GLY E 1 161 ? 54.116  1.928   115.432 1.00 51.26  ? 180 GLY E CA  1 
ATOM   12307 C C   . GLY E 1 161 ? 55.123  2.977   115.042 1.00 50.87  ? 180 GLY E C   1 
ATOM   12308 O O   . GLY E 1 161 ? 54.780  4.027   114.480 1.00 51.00  ? 180 GLY E O   1 
ATOM   12309 N N   . VAL E 1 162 ? 56.387  2.690   115.358 1.00 50.33  ? 181 VAL E N   1 
ATOM   12310 C CA  . VAL E 1 162 ? 57.453  3.671   115.223 1.00 50.53  ? 181 VAL E CA  1 
ATOM   12311 C C   . VAL E 1 162 ? 58.649  3.035   114.543 1.00 49.10  ? 181 VAL E C   1 
ATOM   12312 O O   . VAL E 1 162 ? 58.937  1.851   114.758 1.00 48.38  ? 181 VAL E O   1 
ATOM   12313 C CB  . VAL E 1 162 ? 57.864  4.268   116.588 1.00 52.53  ? 181 VAL E CB  1 
ATOM   12314 C CG1 . VAL E 1 162 ? 58.231  3.186   117.566 1.00 53.83  ? 181 VAL E CG1 1 
ATOM   12315 C CG2 . VAL E 1 162 ? 59.038  5.229   116.409 1.00 53.27  ? 181 VAL E CG2 1 
ATOM   12316 N N   . PHE E 1 163 ? 59.345  3.831   113.738 1.00 51.02  ? 182 PHE E N   1 
ATOM   12317 C CA  . PHE E 1 163 ? 60.550  3.401   113.037 1.00 49.84  ? 182 PHE E CA  1 
ATOM   12318 C C   . PHE E 1 163 ? 61.762  4.004   113.746 1.00 51.51  ? 182 PHE E C   1 
ATOM   12319 O O   . PHE E 1 163 ? 62.006  5.215   113.654 1.00 53.02  ? 182 PHE E O   1 
ATOM   12320 C CB  . PHE E 1 163 ? 60.501  3.826   111.574 1.00 48.53  ? 182 PHE E CB  1 
ATOM   12321 C CG  . PHE E 1 163 ? 61.598  3.264   110.767 1.00 47.41  ? 182 PHE E CG  1 
ATOM   12322 C CD1 . PHE E 1 163 ? 61.454  2.030   110.166 1.00 48.16  ? 182 PHE E CD1 1 
ATOM   12323 C CD2 . PHE E 1 163 ? 62.780  3.958   110.591 1.00 45.81  ? 182 PHE E CD2 1 
ATOM   12324 C CE1 . PHE E 1 163 ? 62.458  1.499   109.397 1.00 46.98  ? 182 PHE E CE1 1 
ATOM   12325 C CE2 . PHE E 1 163 ? 63.822  3.431   109.823 1.00 44.72  ? 182 PHE E CE2 1 
ATOM   12326 C CZ  . PHE E 1 163 ? 63.655  2.194   109.225 1.00 45.11  ? 182 PHE E CZ  1 
ATOM   12327 N N   . MET E 1 164 ? 62.545  3.165   114.434 1.00 51.85  ? 183 MET E N   1 
ATOM   12328 C CA  . MET E 1 164 ? 63.758  3.612   115.170 1.00 53.84  ? 183 MET E CA  1 
ATOM   12329 C C   . MET E 1 164 ? 64.972  3.479   114.241 1.00 52.35  ? 183 MET E C   1 
ATOM   12330 O O   . MET E 1 164 ? 65.524  2.365   114.175 1.00 51.18  ? 183 MET E O   1 
ATOM   12331 C CB  . MET E 1 164 ? 63.950  2.758   116.428 1.00 54.40  ? 183 MET E CB  1 
ATOM   12332 C CG  . MET E 1 164 ? 62.845  2.929   117.451 1.00 56.41  ? 183 MET E CG  1 
ATOM   12333 S SD  . MET E 1 164 ? 63.104  1.974   118.959 1.00 58.96  ? 183 MET E SD  1 
ATOM   12334 C CE  . MET E 1 164 ? 64.606  2.710   119.620 1.00 61.31  ? 183 MET E CE  1 
ATOM   12335 N N   . ASP E 1 165 ? 65.403  4.567   113.596 1.00 51.38  ? 184 ASP E N   1 
ATOM   12336 C CA  . ASP E 1 165 ? 66.496  4.511   112.585 1.00 50.37  ? 184 ASP E CA  1 
ATOM   12337 C C   . ASP E 1 165 ? 67.837  4.964   113.155 1.00 52.44  ? 184 ASP E C   1 
ATOM   12338 O O   . ASP E 1 165 ? 67.798  5.881   113.985 1.00 55.12  ? 184 ASP E O   1 
ATOM   12339 C CB  . ASP E 1 165 ? 66.181  5.403   111.395 1.00 50.24  ? 184 ASP E CB  1 
ATOM   12340 C CG  . ASP E 1 165 ? 67.052  5.212   110.161 1.00 48.38  ? 184 ASP E CG  1 
ATOM   12341 O OD1 . ASP E 1 165 ? 68.088  4.531   110.267 1.00 47.59  ? 184 ASP E OD1 1 
ATOM   12342 O OD2 . ASP E 1 165 ? 66.670  5.721   109.089 1.00 48.26  ? 184 ASP E OD2 1 
ATOM   12343 N N   . ALA E 1 166 ? 68.954  4.349   112.748 1.00 52.05  ? 185 ALA E N   1 
ATOM   12344 C CA  . ALA E 1 166 ? 70.336  4.772   113.102 1.00 53.68  ? 185 ALA E CA  1 
ATOM   12345 C C   . ALA E 1 166 ? 70.981  3.830   114.117 1.00 54.50  ? 185 ALA E C   1 
ATOM   12346 O O   . ALA E 1 166 ? 72.019  4.238   114.645 1.00 56.82  ? 185 ALA E O   1 
ATOM   12347 C CB  . ALA E 1 166 ? 70.405  6.210   113.596 1.00 56.65  ? 185 ALA E CB  1 
ATOM   12348 N N   . PHE E 1 167 ? 70.440  2.638   114.388 1.00 53.56  ? 186 PHE E N   1 
ATOM   12349 C CA  . PHE E 1 167 ? 71.145  1.704   115.263 1.00 54.38  ? 186 PHE E CA  1 
ATOM   12350 C C   . PHE E 1 167 ? 72.596  1.500   114.842 1.00 54.42  ? 186 PHE E C   1 
ATOM   12351 O O   . PHE E 1 167 ? 73.486  1.653   115.685 1.00 57.10  ? 186 PHE E O   1 
ATOM   12352 C CB  . PHE E 1 167 ? 70.429  0.344   115.305 1.00 52.42  ? 186 PHE E CB  1 
ATOM   12353 C CG  . PHE E 1 167 ? 69.200  0.325   116.149 1.00 53.15  ? 186 PHE E CG  1 
ATOM   12354 C CD1 . PHE E 1 167 ? 68.500  1.477   116.407 1.00 54.74  ? 186 PHE E CD1 1 
ATOM   12355 C CD2 . PHE E 1 167 ? 68.744  -0.845  116.674 1.00 52.86  ? 186 PHE E CD2 1 
ATOM   12356 C CE1 . PHE E 1 167 ? 67.366  1.457   117.193 1.00 55.29  ? 186 PHE E CE1 1 
ATOM   12357 C CE2 . PHE E 1 167 ? 67.612  -0.879  117.448 1.00 54.34  ? 186 PHE E CE2 1 
ATOM   12358 C CZ  . PHE E 1 167 ? 66.925  0.278   117.712 1.00 54.91  ? 186 PHE E CZ  1 
ATOM   12359 N N   . PRO E 1 168 ? 72.906  1.196   113.586 1.00 54.61  ? 187 PRO E N   1 
ATOM   12360 C CA  . PRO E 1 168 ? 74.314  0.959   113.227 1.00 54.66  ? 187 PRO E CA  1 
ATOM   12361 C C   . PRO E 1 168 ? 75.227  2.134   113.536 1.00 57.59  ? 187 PRO E C   1 
ATOM   12362 O O   . PRO E 1 168 ? 76.401  1.935   113.855 1.00 59.22  ? 187 PRO E O   1 
ATOM   12363 C CB  . PRO E 1 168 ? 74.244  0.678   111.718 1.00 51.67  ? 187 PRO E CB  1 
ATOM   12364 C CG  . PRO E 1 168 ? 72.846  0.233   111.482 1.00 50.09  ? 187 PRO E CG  1 
ATOM   12365 C CD  . PRO E 1 168 ? 72.005  1.014   112.439 1.00 52.30  ? 187 PRO E CD  1 
ATOM   12366 N N   . GLN E 1 169 ? 74.710  3.358   113.446 1.00 57.84  ? 188 GLN E N   1 
ATOM   12367 C CA  . GLN E 1 169 ? 75.527  4.542   113.703 1.00 59.91  ? 188 GLN E CA  1 
ATOM   12368 C C   . GLN E 1 169 ? 75.879  4.662   115.175 1.00 63.39  ? 188 GLN E C   1 
ATOM   12369 O O   . GLN E 1 169 ? 77.003  5.034   115.526 1.00 65.21  ? 188 GLN E O   1 
ATOM   12370 C CB  . GLN E 1 169 ? 74.777  5.785   113.242 1.00 59.95  ? 188 GLN E CB  1 
ATOM   12371 C CG  . GLN E 1 169 ? 74.533  5.806   111.761 1.00 57.37  ? 188 GLN E CG  1 
ATOM   12372 C CD  . GLN E 1 169 ? 73.653  6.944   111.354 1.00 57.67  ? 188 GLN E CD  1 
ATOM   12373 O OE1 . GLN E 1 169 ? 74.012  8.123   111.541 1.00 59.55  ? 188 GLN E OE1 1 
ATOM   12374 N NE2 . GLN E 1 169 ? 72.478  6.619   110.805 1.00 56.40  ? 188 GLN E NE2 1 
ATOM   12375 N N   . ILE E 1 170 ? 74.912  4.365   116.034 1.00 58.94  ? 189 ILE E N   1 
ATOM   12376 C CA  . ILE E 1 170 ? 75.134  4.273   117.469 1.00 62.31  ? 189 ILE E CA  1 
ATOM   12377 C C   . ILE E 1 170 ? 76.259  3.301   117.789 1.00 62.81  ? 189 ILE E C   1 
ATOM   12378 O O   . ILE E 1 170 ? 77.152  3.604   118.588 1.00 65.81  ? 189 ILE E O   1 
ATOM   12379 C CB  . ILE E 1 170 ? 73.816  3.870   118.159 1.00 62.78  ? 189 ILE E CB  1 
ATOM   12380 C CG1 . ILE E 1 170 ? 72.770  4.936   117.814 1.00 63.03  ? 189 ILE E CG1 1 
ATOM   12381 C CG2 . ILE E 1 170 ? 74.031  3.663   119.641 1.00 66.51  ? 189 ILE E CG2 1 
ATOM   12382 C CD1 . ILE E 1 170 ? 71.501  4.873   118.629 1.00 62.52  ? 189 ILE E CD1 1 
ATOM   12383 N N   . ALA E 1 171 ? 76.226  2.120   117.192 1.00 61.40  ? 190 ALA E N   1 
ATOM   12384 C CA  . ALA E 1 171 ? 77.198  1.090   117.513 1.00 61.96  ? 190 ALA E CA  1 
ATOM   12385 C C   . ALA E 1 171 ? 78.506  1.245   116.755 1.00 61.70  ? 190 ALA E C   1 
ATOM   12386 O O   . ALA E 1 171 ? 79.400  0.393   116.897 1.00 62.59  ? 190 ALA E O   1 
ATOM   12387 C CB  . ALA E 1 171 ? 76.613  -0.286  117.218 1.00 58.81  ? 190 ALA E CB  1 
ATOM   12388 N N   . SER E 1 172 ? 78.635  2.290   115.947 1.00 60.91  ? 191 SER E N   1 
ATOM   12389 C CA  . SER E 1 172 ? 79.862  2.489   115.195 1.00 60.20  ? 191 SER E CA  1 
ATOM   12390 C C   . SER E 1 172 ? 81.029  2.555   116.171 1.00 63.63  ? 191 SER E C   1 
ATOM   12391 O O   . SER E 1 172 ? 81.044  3.384   117.089 1.00 65.88  ? 191 SER E O   1 
ATOM   12392 C CB  . SER E 1 172 ? 79.755  3.754   114.351 1.00 59.78  ? 191 SER E CB  1 
ATOM   12393 O OG  . SER E 1 172 ? 80.934  3.962   113.600 1.00 59.89  ? 191 SER E OG  1 
ATOM   12394 N N   . GLN E 1 173 ? 81.982  1.637   116.004 1.00 61.73  ? 192 GLN E N   1 
ATOM   12395 C CA  . GLN E 1 173 ? 83.125  1.560   116.915 1.00 65.03  ? 192 GLN E CA  1 
ATOM   12396 C C   . GLN E 1 173 ? 83.966  2.823   116.884 1.00 66.40  ? 192 GLN E C   1 
ATOM   12397 O O   . GLN E 1 173 ? 84.768  3.049   117.794 1.00 69.43  ? 192 GLN E O   1 
ATOM   12398 C CB  . GLN E 1 173 ? 83.976  0.338   116.561 1.00 64.17  ? 192 GLN E CB  1 
ATOM   12399 C CG  . GLN E 1 173 ? 83.262  -0.959  116.846 1.00 64.02  ? 192 GLN E CG  1 
ATOM   12400 C CD  . GLN E 1 173 ? 83.060  -1.139  118.317 1.00 67.92  ? 192 GLN E CD  1 
ATOM   12401 O OE1 . GLN E 1 173 ? 83.975  -0.916  119.096 1.00 71.07  ? 192 GLN E OE1 1 
ATOM   12402 N NE2 . GLN E 1 173 ? 81.849  -1.511  118.716 1.00 67.96  ? 192 GLN E NE2 1 
ATOM   12403 N N   . ALA E 1 174 ? 83.794  3.638   115.847 1.00 64.36  ? 193 ALA E N   1 
ATOM   12404 C CA  . ALA E 1 174 ? 84.495  4.907   115.761 1.00 65.27  ? 193 ALA E CA  1 
ATOM   12405 C C   . ALA E 1 174 ? 84.041  5.868   116.848 1.00 67.44  ? 193 ALA E C   1 
ATOM   12406 O O   . ALA E 1 174 ? 84.818  6.730   117.278 1.00 69.34  ? 193 ALA E O   1 
ATOM   12407 C CB  . ALA E 1 174 ? 84.268  5.519   114.382 1.00 62.95  ? 193 ALA E CB  1 
ATOM   12408 N N   . ASN E 1 175 ? 82.795  5.733   117.309 1.00 66.05  ? 194 ASN E N   1 
ATOM   12409 C CA  . ASN E 1 175 ? 82.317  6.588   118.389 1.00 68.39  ? 194 ASN E CA  1 
ATOM   12410 C C   . ASN E 1 175 ? 83.162  6.449   119.643 1.00 71.54  ? 194 ASN E C   1 
ATOM   12411 O O   . ASN E 1 175 ? 83.199  7.370   120.466 1.00 74.00  ? 194 ASN E O   1 
ATOM   12412 C CB  . ASN E 1 175 ? 80.870  6.261   118.708 1.00 68.11  ? 194 ASN E CB  1 
ATOM   12413 C CG  . ASN E 1 175 ? 79.959  6.597   117.576 1.00 65.57  ? 194 ASN E CG  1 
ATOM   12414 O OD1 . ASN E 1 175 ? 80.269  7.474   116.765 1.00 64.78  ? 194 ASN E OD1 1 
ATOM   12415 N ND2 . ASN E 1 175 ? 78.818  5.910   117.504 1.00 64.52  ? 194 ASN E ND2 1 
ATOM   12416 N N   . ARG E 1 176 ? 83.824  5.304   119.819 1.00 69.28  ? 195 ARG E N   1 
ATOM   12417 C CA  . ARG E 1 176 ? 84.711  5.121   120.963 1.00 72.40  ? 195 ARG E CA  1 
ATOM   12418 C C   . ARG E 1 176 ? 85.816  6.170   120.972 1.00 73.98  ? 195 ARG E C   1 
ATOM   12419 O O   . ARG E 1 176 ? 86.100  6.764   122.011 1.00 77.24  ? 195 ARG E O   1 
ATOM   12420 C CB  . ARG E 1 176 ? 85.295  3.711   120.935 1.00 72.24  ? 195 ARG E CB  1 
ATOM   12421 C CG  . ARG E 1 176 ? 84.260  2.637   121.189 1.00 71.97  ? 195 ARG E CG  1 
ATOM   12422 C CD  . ARG E 1 176 ? 84.867  1.244   121.189 1.00 72.03  ? 195 ARG E CD  1 
ATOM   12423 N NE  . ARG E 1 176 ? 84.482  0.547   122.412 1.00 74.52  ? 195 ARG E NE  1 
ATOM   12424 C CZ  . ARG E 1 176 ? 84.545  -0.765  122.595 1.00 74.53  ? 195 ARG E CZ  1 
ATOM   12425 N NH1 . ARG E 1 176 ? 84.990  -1.575  121.644 1.00 72.41  ? 195 ARG E NH1 1 
ATOM   12426 N NH2 . ARG E 1 176 ? 84.151  -1.276  123.763 1.00 76.11  ? 195 ARG E NH2 1 
ATOM   12427 N N   . LYS E 1 177 ? 86.445  6.413   119.821 1.00 65.31  ? 196 LYS E N   1 
ATOM   12428 C CA  . LYS E 1 177 ? 87.428  7.481   119.722 1.00 67.59  ? 196 LYS E CA  1 
ATOM   12429 C C   . LYS E 1 177 ? 86.826  8.811   120.131 1.00 71.12  ? 196 LYS E C   1 
ATOM   12430 O O   . LYS E 1 177 ? 87.533  9.675   120.656 1.00 75.89  ? 196 LYS E O   1 
ATOM   12431 C CB  . LYS E 1 177 ? 87.985  7.565   118.301 1.00 64.30  ? 196 LYS E CB  1 
ATOM   12432 N N   . LEU E 1 178 ? 85.520  8.982   119.943 1.00 70.75  ? 197 LEU E N   1 
ATOM   12433 C CA  . LEU E 1 178 ? 84.888  10.239  120.315 1.00 72.70  ? 197 LEU E CA  1 
ATOM   12434 C C   . LEU E 1 178 ? 84.571  10.312  121.803 1.00 77.04  ? 197 LEU E C   1 
ATOM   12435 O O   . LEU E 1 178 ? 84.741  11.368  122.423 1.00 81.16  ? 197 LEU E O   1 
ATOM   12436 C CB  . LEU E 1 178 ? 83.586  10.432  119.539 1.00 70.17  ? 197 LEU E CB  1 
ATOM   12437 C CG  . LEU E 1 178 ? 83.620  10.972  118.113 1.00 68.21  ? 197 LEU E CG  1 
ATOM   12438 C CD1 . LEU E 1 178 ? 82.276  10.736  117.490 1.00 66.82  ? 197 LEU E CD1 1 
ATOM   12439 C CD2 . LEU E 1 178 ? 83.969  12.451  118.097 1.00 69.75  ? 197 LEU E CD2 1 
ATOM   12440 N N   . TRP E 1 179 ? 84.068  9.223   122.383 1.00 76.98  ? 198 TRP E N   1 
ATOM   12441 C CA  . TRP E 1 179 ? 83.466  9.262   123.705 1.00 80.40  ? 198 TRP E CA  1 
ATOM   12442 C C   . TRP E 1 179 ? 84.325  8.663   124.795 1.00 84.45  ? 198 TRP E C   1 
ATOM   12443 O O   . TRP E 1 179 ? 84.178  9.036   125.962 1.00 88.13  ? 198 TRP E O   1 
ATOM   12444 C CB  . TRP E 1 179 ? 82.133  8.505   123.700 1.00 78.34  ? 198 TRP E CB  1 
ATOM   12445 C CG  . TRP E 1 179 ? 81.172  9.005   122.698 1.00 75.86  ? 198 TRP E CG  1 
ATOM   12446 C CD1 . TRP E 1 179 ? 81.092  10.269  122.189 1.00 75.45  ? 198 TRP E CD1 1 
ATOM   12447 C CD2 . TRP E 1 179 ? 80.128  8.256   122.080 1.00 73.67  ? 198 TRP E CD2 1 
ATOM   12448 N NE1 . TRP E 1 179 ? 80.054  10.350  121.288 1.00 73.18  ? 198 TRP E NE1 1 
ATOM   12449 C CE2 . TRP E 1 179 ? 79.451  9.125   121.202 1.00 72.11  ? 198 TRP E CE2 1 
ATOM   12450 C CE3 . TRP E 1 179 ? 79.702  6.927   122.175 1.00 72.98  ? 198 TRP E CE3 1 
ATOM   12451 C CZ2 . TRP E 1 179 ? 78.372  8.704   120.420 1.00 69.73  ? 198 TRP E CZ2 1 
ATOM   12452 C CZ3 . TRP E 1 179 ? 78.624  6.513   121.398 1.00 70.78  ? 198 TRP E CZ3 1 
ATOM   12453 C CH2 . TRP E 1 179 ? 77.973  7.399   120.537 1.00 69.22  ? 198 TRP E CH2 1 
ATOM   12454 N N   . GLY E 1 180 ? 85.222  7.764   124.441 1.00 81.49  ? 199 GLY E N   1 
ATOM   12455 C CA  . GLY E 1 180 ? 85.823  6.893   125.416 1.00 84.62  ? 199 GLY E CA  1 
ATOM   12456 C C   . GLY E 1 180 ? 84.919  5.711   125.693 1.00 82.23  ? 199 GLY E C   1 
ATOM   12457 O O   . GLY E 1 180 ? 83.720  5.736   125.435 1.00 79.39  ? 199 GLY E O   1 
ATOM   12458 N N   . ASP E 1 181 ? 85.517  4.642   126.211 1.00 85.33  ? 200 ASP E N   1 
ATOM   12459 C CA  . ASP E 1 181 ? 84.755  3.407   126.308 1.00 84.70  ? 200 ASP E CA  1 
ATOM   12460 C C   . ASP E 1 181 ? 83.648  3.522   127.348 1.00 86.19  ? 200 ASP E C   1 
ATOM   12461 O O   . ASP E 1 181 ? 82.519  3.107   127.092 1.00 84.47  ? 200 ASP E O   1 
ATOM   12462 C CB  . ASP E 1 181 ? 85.682  2.225   126.597 1.00 85.68  ? 200 ASP E CB  1 
ATOM   12463 C CG  . ASP E 1 181 ? 86.318  1.673   125.318 1.00 84.19  ? 200 ASP E CG  1 
ATOM   12464 O OD1 . ASP E 1 181 ? 86.660  2.492   124.427 1.00 83.68  ? 200 ASP E OD1 1 
ATOM   12465 O OD2 . ASP E 1 181 ? 86.428  0.434   125.175 1.00 83.79  ? 200 ASP E OD2 1 
ATOM   12466 N N   . GLU E 1 182 ? 83.937  4.082   128.523 1.00 89.83  ? 201 GLU E N   1 
ATOM   12467 C CA  . GLU E 1 182 ? 82.897  4.170   129.545 1.00 92.12  ? 201 GLU E CA  1 
ATOM   12468 C C   . GLU E 1 182 ? 81.609  4.723   128.936 1.00 89.89  ? 201 GLU E C   1 
ATOM   12469 O O   . GLU E 1 182 ? 80.552  4.084   128.996 1.00 88.65  ? 201 GLU E O   1 
ATOM   12470 C CB  . GLU E 1 182 ? 83.375  5.021   130.729 1.00 97.29  ? 201 GLU E CB  1 
ATOM   12471 N N   . LYS E 1 183 ? 81.691  5.892   128.295 1.00 89.14  ? 202 LYS E N   1 
ATOM   12472 C CA  . LYS E 1 183 ? 80.483  6.521   127.764 1.00 87.03  ? 202 LYS E CA  1 
ATOM   12473 C C   . LYS E 1 183 ? 79.977  5.778   126.540 1.00 81.80  ? 202 LYS E C   1 
ATOM   12474 O O   . LYS E 1 183 ? 78.768  5.717   126.309 1.00 80.13  ? 202 LYS E O   1 
ATOM   12475 C CB  . LYS E 1 183 ? 80.751  7.994   127.444 1.00 87.49  ? 202 LYS E CB  1 
ATOM   12476 C CG  . LYS E 1 183 ? 79.588  8.756   126.812 1.00 85.26  ? 202 LYS E CG  1 
ATOM   12477 C CD  . LYS E 1 183 ? 78.341  8.798   127.687 1.00 87.11  ? 202 LYS E CD  1 
ATOM   12478 C CE  . LYS E 1 183 ? 78.264  10.075  128.501 1.00 90.76  ? 202 LYS E CE  1 
ATOM   12479 N NZ  . LYS E 1 183 ? 77.166  9.955   129.503 1.00 92.95  ? 202 LYS E NZ  1 
ATOM   12480 N N   . PHE E 1 184 ? 80.878  5.181   125.765 1.00 81.93  ? 203 PHE E N   1 
ATOM   12481 C CA  . PHE E 1 184 ? 80.442  4.347   124.657 1.00 79.21  ? 203 PHE E CA  1 
ATOM   12482 C C   . PHE E 1 184 ? 79.594  3.167   125.133 1.00 79.11  ? 203 PHE E C   1 
ATOM   12483 O O   . PHE E 1 184 ? 78.521  2.903   124.577 1.00 77.20  ? 203 PHE E O   1 
ATOM   12484 C CB  . PHE E 1 184 ? 81.639  3.835   123.878 1.00 78.40  ? 203 PHE E CB  1 
ATOM   12485 C CG  . PHE E 1 184 ? 81.256  2.964   122.743 1.00 75.19  ? 203 PHE E CG  1 
ATOM   12486 C CD1 . PHE E 1 184 ? 81.028  3.507   121.480 1.00 72.77  ? 203 PHE E CD1 1 
ATOM   12487 C CD2 . PHE E 1 184 ? 81.084  1.605   122.929 1.00 75.23  ? 203 PHE E CD2 1 
ATOM   12488 C CE1 . PHE E 1 184 ? 80.663  2.702   120.412 1.00 69.96  ? 203 PHE E CE1 1 
ATOM   12489 C CE2 . PHE E 1 184 ? 80.719  0.801   121.872 1.00 72.48  ? 203 PHE E CE2 1 
ATOM   12490 C CZ  . PHE E 1 184 ? 80.511  1.350   120.609 1.00 69.58  ? 203 PHE E CZ  1 
ATOM   12491 N N   . GLU E 1 185 ? 80.077  2.423   126.141 1.00 80.74  ? 204 GLU E N   1 
ATOM   12492 C CA  . GLU E 1 185 ? 79.355  1.236   126.592 1.00 80.04  ? 204 GLU E CA  1 
ATOM   12493 C C   . GLU E 1 185 ? 77.987  1.614   127.160 1.00 80.40  ? 204 GLU E C   1 
ATOM   12494 O O   . GLU E 1 185 ? 76.999  0.890   126.971 1.00 78.98  ? 204 GLU E O   1 
ATOM   12495 C CB  . GLU E 1 185 ? 80.146  0.471   127.665 1.00 82.99  ? 204 GLU E CB  1 
ATOM   12496 C CG  . GLU E 1 185 ? 81.677  0.291   127.463 1.00 83.94  ? 204 GLU E CG  1 
ATOM   12497 C CD  . GLU E 1 185 ? 82.062  -1.018  126.742 1.00 81.92  ? 204 GLU E CD  1 
ATOM   12498 O OE1 . GLU E 1 185 ? 83.288  -1.197  126.464 1.00 79.45  ? 204 GLU E OE1 1 
ATOM   12499 O OE2 . GLU E 1 185 ? 81.172  -1.843  126.452 1.00 83.01  ? 204 GLU E OE2 1 
ATOM   12500 N N   . ALA E 1 186 ? 77.922  2.737   127.885 1.00 82.90  ? 205 ALA E N   1 
ATOM   12501 C CA  . ALA E 1 186 ? 76.673  3.165   128.512 1.00 84.34  ? 205 ALA E CA  1 
ATOM   12502 C C   . ALA E 1 186 ? 75.629  3.539   127.472 1.00 80.77  ? 205 ALA E C   1 
ATOM   12503 O O   . ALA E 1 186 ? 74.432  3.304   127.663 1.00 80.61  ? 205 ALA E O   1 
ATOM   12504 C CB  . ALA E 1 186 ? 76.935  4.361   129.424 1.00 88.09  ? 205 ALA E CB  1 
ATOM   12505 N N   . ILE E 1 187 ? 76.072  4.180   126.391 1.00 80.08  ? 206 ILE E N   1 
ATOM   12506 C CA  . ILE E 1 187 ? 75.186  4.505   125.286 1.00 77.77  ? 206 ILE E CA  1 
ATOM   12507 C C   . ILE E 1 187 ? 74.669  3.220   124.645 1.00 75.08  ? 206 ILE E C   1 
ATOM   12508 O O   . ILE E 1 187 ? 73.488  3.128   124.284 1.00 73.00  ? 206 ILE E O   1 
ATOM   12509 C CB  . ILE E 1 187 ? 75.923  5.425   124.289 1.00 77.71  ? 206 ILE E CB  1 
ATOM   12510 C CG1 . ILE E 1 187 ? 76.009  6.840   124.877 1.00 79.60  ? 206 ILE E CG1 1 
ATOM   12511 C CG2 . ILE E 1 187 ? 75.233  5.419   122.931 1.00 74.98  ? 206 ILE E CG2 1 
ATOM   12512 C CD1 . ILE E 1 187 ? 76.777  7.839   124.033 1.00 79.11  ? 206 ILE E CD1 1 
ATOM   12513 N N   . GLN E 1 188 ? 75.533  2.195   124.532 1.00 78.25  ? 207 GLN E N   1 
ATOM   12514 C CA  . GLN E 1 188 ? 75.088  0.896   124.036 1.00 74.89  ? 207 GLN E CA  1 
ATOM   12515 C C   . GLN E 1 188 ? 74.049  0.282   124.966 1.00 74.76  ? 207 GLN E C   1 
ATOM   12516 O O   . GLN E 1 188 ? 73.056  -0.300  124.510 1.00 72.87  ? 207 GLN E O   1 
ATOM   12517 C CB  . GLN E 1 188 ? 76.269  -0.061  123.907 1.00 74.62  ? 207 GLN E CB  1 
ATOM   12518 C CG  . GLN E 1 188 ? 77.396  0.408   123.029 1.00 75.86  ? 207 GLN E CG  1 
ATOM   12519 C CD  . GLN E 1 188 ? 76.925  1.103   121.774 1.00 74.54  ? 207 GLN E CD  1 
ATOM   12520 O OE1 . GLN E 1 188 ? 75.928  0.707   121.161 1.00 75.01  ? 207 GLN E OE1 1 
ATOM   12521 N NE2 . GLN E 1 188 ? 77.645  2.147   121.372 1.00 70.76  ? 207 GLN E NE2 1 
ATOM   12522 N N   . GLN E 1 189 ? 74.285  0.358   126.277 1.00 76.33  ? 208 GLN E N   1 
ATOM   12523 C CA  . GLN E 1 189 ? 73.259  -0.061  127.221 1.00 78.40  ? 208 GLN E CA  1 
ATOM   12524 C C   . GLN E 1 189 ? 72.030  0.826   127.078 1.00 77.65  ? 208 GLN E C   1 
ATOM   12525 O O   . GLN E 1 189 ? 70.891  0.363   127.210 1.00 77.39  ? 208 GLN E O   1 
ATOM   12526 C CB  . GLN E 1 189 ? 73.790  -0.012  128.656 1.00 83.25  ? 208 GLN E CB  1 
ATOM   12527 C CG  . GLN E 1 189 ? 73.918  -1.365  129.376 1.00 85.40  ? 208 GLN E CG  1 
ATOM   12528 C CD  . GLN E 1 189 ? 72.701  -2.267  129.225 1.00 84.74  ? 208 GLN E CD  1 
ATOM   12529 O OE1 . GLN E 1 189 ? 71.598  -1.807  128.926 1.00 84.59  ? 208 GLN E OE1 1 
ATOM   12530 N NE2 . GLN E 1 189 ? 72.901  -3.565  129.433 1.00 85.23  ? 208 GLN E NE2 1 
ATOM   12531 N N   . GLY E 1 190 ? 72.245  2.121   126.797 1.00 79.07  ? 209 GLY E N   1 
ATOM   12532 C CA  . GLY E 1 190 ? 71.138  3.063   126.743 1.00 78.60  ? 209 GLY E CA  1 
ATOM   12533 C C   . GLY E 1 190 ? 70.217  2.824   125.568 1.00 74.47  ? 209 GLY E C   1 
ATOM   12534 O O   . GLY E 1 190 ? 69.030  3.157   125.621 1.00 74.68  ? 209 GLY E O   1 
ATOM   12535 N N   . LEU E 1 191 ? 70.747  2.242   124.495 1.00 74.92  ? 210 LEU E N   1 
ATOM   12536 C CA  . LEU E 1 191 ? 69.905  1.834   123.375 1.00 71.22  ? 210 LEU E CA  1 
ATOM   12537 C C   . LEU E 1 191 ? 69.025  0.651   123.763 1.00 71.68  ? 210 LEU E C   1 
ATOM   12538 O O   . LEU E 1 191 ? 67.822  0.639   123.480 1.00 70.67  ? 210 LEU E O   1 
ATOM   12539 C CB  . LEU E 1 191 ? 70.794  1.503   122.182 1.00 69.15  ? 210 LEU E CB  1 
ATOM   12540 C CG  . LEU E 1 191 ? 70.098  0.967   120.936 1.00 65.30  ? 210 LEU E CG  1 
ATOM   12541 C CD1 . LEU E 1 191 ? 69.056  1.966   120.462 1.00 65.19  ? 210 LEU E CD1 1 
ATOM   12542 C CD2 . LEU E 1 191 ? 71.112  0.672   119.847 1.00 64.05  ? 210 LEU E CD2 1 
ATOM   12543 N N   . GLN E 1 192 ? 69.608  -0.345  124.430 1.00 74.51  ? 211 GLN E N   1 
ATOM   12544 C CA  . GLN E 1 192 ? 68.822  -1.437  124.992 1.00 75.67  ? 211 GLN E CA  1 
ATOM   12545 C C   . GLN E 1 192 ? 67.726  -0.906  125.897 1.00 77.83  ? 211 GLN E C   1 
ATOM   12546 O O   . GLN E 1 192 ? 66.619  -1.455  125.946 1.00 77.53  ? 211 GLN E O   1 
ATOM   12547 C CB  . GLN E 1 192 ? 69.735  -2.362  125.803 1.00 78.21  ? 211 GLN E CB  1 
ATOM   12548 C CG  . GLN E 1 192 ? 70.240  -3.612  125.103 1.00 76.72  ? 211 GLN E CG  1 
ATOM   12549 C CD  . GLN E 1 192 ? 69.374  -4.814  125.428 1.00 77.46  ? 211 GLN E CD  1 
ATOM   12550 O OE1 . GLN E 1 192 ? 68.147  -4.764  125.278 1.00 77.77  ? 211 GLN E OE1 1 
ATOM   12551 N NE2 . GLN E 1 192 ? 70.002  -5.888  125.916 1.00 79.00  ? 211 GLN E NE2 1 
ATOM   12552 N N   . ASP E 1 193 ? 68.043  0.140   126.657 1.00 73.80  ? 212 ASP E N   1 
ATOM   12553 C CA  . ASP E 1 193 ? 67.100  0.699   127.616 1.00 76.51  ? 212 ASP E CA  1 
ATOM   12554 C C   . ASP E 1 193 ? 65.986  1.456   126.908 1.00 74.54  ? 212 ASP E C   1 
ATOM   12555 O O   . ASP E 1 193 ? 64.819  1.388   127.310 1.00 75.56  ? 212 ASP E O   1 
ATOM   12556 C CB  . ASP E 1 193 ? 67.836  1.633   128.585 1.00 79.98  ? 212 ASP E CB  1 
ATOM   12557 C CG  . ASP E 1 193 ? 68.870  0.908   129.456 1.00 83.48  ? 212 ASP E CG  1 
ATOM   12558 O OD1 . ASP E 1 193 ? 69.654  1.589   130.187 1.00 85.37  ? 212 ASP E OD1 1 
ATOM   12559 O OD2 . ASP E 1 193 ? 68.892  -0.344  129.415 1.00 85.36  ? 212 ASP E OD2 1 
ATOM   12560 N N   . ILE E 1 194 ? 66.336  2.193   125.853 1.00 75.52  ? 213 ILE E N   1 
ATOM   12561 C CA  . ILE E 1 194 ? 65.353  3.016   125.153 1.00 73.96  ? 213 ILE E CA  1 
ATOM   12562 C C   . ILE E 1 194 ? 64.360  2.152   124.385 1.00 71.38  ? 213 ILE E C   1 
ATOM   12563 O O   . ILE E 1 194 ? 63.190  2.526   124.236 1.00 71.24  ? 213 ILE E O   1 
ATOM   12564 C CB  . ILE E 1 194 ? 66.095  4.009   124.239 1.00 72.10  ? 213 ILE E CB  1 
ATOM   12565 C CG1 . ILE E 1 194 ? 65.259  5.272   124.013 1.00 72.00  ? 213 ILE E CG1 1 
ATOM   12566 C CG2 . ILE E 1 194 ? 66.403  3.360   122.911 1.00 68.47  ? 213 ILE E CG2 1 
ATOM   12567 C CD1 . ILE E 1 194 ? 65.990  6.350   123.220 1.00 71.33  ? 213 ILE E CD1 1 
ATOM   12568 N N   . ILE E 1 195 ? 64.791  0.984   123.905 1.00 70.64  ? 214 ILE E N   1 
ATOM   12569 C CA  . ILE E 1 195 ? 63.870  0.071   123.236 1.00 68.55  ? 214 ILE E CA  1 
ATOM   12570 C C   . ILE E 1 195 ? 62.884  -0.516  124.239 1.00 71.05  ? 214 ILE E C   1 
ATOM   12571 O O   . ILE E 1 195 ? 61.689  -0.666  123.946 1.00 70.33  ? 214 ILE E O   1 
ATOM   12572 C CB  . ILE E 1 195 ? 64.660  -1.030  122.510 1.00 66.68  ? 214 ILE E CB  1 
ATOM   12573 C CG1 . ILE E 1 195 ? 65.506  -0.433  121.386 1.00 64.12  ? 214 ILE E CG1 1 
ATOM   12574 C CG2 . ILE E 1 195 ? 63.724  -2.070  121.928 1.00 65.55  ? 214 ILE E CG2 1 
ATOM   12575 C CD1 . ILE E 1 195 ? 66.605  -1.335  120.877 1.00 63.09  ? 214 ILE E CD1 1 
ATOM   12576 N N   . GLN E 1 196 ? 63.373  -0.879  125.429 1.00 69.46  ? 215 GLN E N   1 
ATOM   12577 C CA  . GLN E 1 196 ? 62.497  -1.298  126.513 1.00 72.19  ? 215 GLN E CA  1 
ATOM   12578 C C   . GLN E 1 196 ? 61.419  -0.261  126.769 1.00 73.31  ? 215 GLN E C   1 
ATOM   12579 O O   . GLN E 1 196 ? 60.231  -0.580  126.875 1.00 73.61  ? 215 GLN E O   1 
ATOM   12580 C CB  . GLN E 1 196 ? 63.330  -1.496  127.781 1.00 75.78  ? 215 GLN E CB  1 
ATOM   12581 C CG  . GLN E 1 196 ? 63.028  -2.747  128.561 1.00 77.58  ? 215 GLN E CG  1 
ATOM   12582 C CD  . GLN E 1 196 ? 63.775  -2.823  129.859 1.00 81.35  ? 215 GLN E CD  1 
ATOM   12583 O OE1 . GLN E 1 196 ? 64.180  -1.807  130.416 1.00 83.30  ? 215 GLN E OE1 1 
ATOM   12584 N NE2 . GLN E 1 196 ? 63.971  -4.036  130.353 1.00 82.74  ? 215 GLN E NE2 1 
ATOM   12585 N N   . GLU E 1 197 ? 61.843  0.995   126.903 1.00 74.21  ? 216 GLU E N   1 
ATOM   12586 C CA  . GLU E 1 197 ? 60.959  2.057   127.359 1.00 75.62  ? 216 GLU E CA  1 
ATOM   12587 C C   . GLU E 1 197 ? 60.012  2.501   126.264 1.00 72.64  ? 216 GLU E C   1 
ATOM   12588 O O   . GLU E 1 197 ? 58.933  3.039   126.555 1.00 73.56  ? 216 GLU E O   1 
ATOM   12589 C CB  . GLU E 1 197 ? 61.809  3.229   127.801 1.00 77.50  ? 216 GLU E CB  1 
ATOM   12590 C CG  . GLU E 1 197 ? 61.051  4.353   128.444 1.00 81.34  ? 216 GLU E CG  1 
ATOM   12591 C CD  . GLU E 1 197 ? 61.968  5.166   129.315 1.00 82.72  ? 216 GLU E CD  1 
ATOM   12592 O OE1 . GLU E 1 197 ? 63.097  5.451   128.844 1.00 81.70  ? 216 GLU E OE1 1 
ATOM   12593 O OE2 . GLU E 1 197 ? 61.580  5.482   130.471 1.00 85.05  ? 216 GLU E OE2 1 
ATOM   12594 N N   . THR E 1 198 ? 60.432  2.354   125.005 1.00 71.85  ? 217 THR E N   1 
ATOM   12595 C CA  . THR E 1 198 ? 59.521  2.500   123.879 1.00 69.10  ? 217 THR E CA  1 
ATOM   12596 C C   . THR E 1 198 ? 58.401  1.468   123.960 1.00 69.04  ? 217 THR E C   1 
ATOM   12597 O O   . THR E 1 198 ? 57.215  1.815   123.986 1.00 69.52  ? 217 THR E O   1 
ATOM   12598 C CB  . THR E 1 198 ? 60.304  2.376   122.571 1.00 65.69  ? 217 THR E CB  1 
ATOM   12599 O OG1 . THR E 1 198 ? 61.195  3.500   122.458 1.00 65.86  ? 217 THR E OG1 1 
ATOM   12600 C CG2 . THR E 1 198 ? 59.358  2.325   121.379 1.00 63.32  ? 217 THR E CG2 1 
ATOM   12601 N N   . ARG E 1 199 ? 58.760  0.187   124.033 1.00 66.66  ? 218 ARG E N   1 
ATOM   12602 C CA  . ARG E 1 199 ? 57.741  -0.848  124.166 1.00 66.93  ? 218 ARG E CA  1 
ATOM   12603 C C   . ARG E 1 199 ? 56.836  -0.571  125.363 1.00 70.18  ? 218 ARG E C   1 
ATOM   12604 O O   . ARG E 1 199 ? 55.610  -0.670  125.261 1.00 70.14  ? 218 ARG E O   1 
ATOM   12605 C CB  . ARG E 1 199 ? 58.406  -2.217  124.273 1.00 66.93  ? 218 ARG E CB  1 
ATOM   12606 C CG  . ARG E 1 199 ? 57.427  -3.354  124.560 1.00 67.87  ? 218 ARG E CG  1 
ATOM   12607 C CD  . ARG E 1 199 ? 56.342  -3.489  123.504 1.00 65.48  ? 218 ARG E CD  1 
ATOM   12608 N NE  . ARG E 1 199 ? 56.928  -3.863  122.222 1.00 62.20  ? 218 ARG E NE  1 
ATOM   12609 C CZ  . ARG E 1 199 ? 56.360  -3.649  121.044 1.00 59.64  ? 218 ARG E CZ  1 
ATOM   12610 N NH1 . ARG E 1 199 ? 55.151  -3.121  120.945 1.00 59.83  ? 218 ARG E NH1 1 
ATOM   12611 N NH2 . ARG E 1 199 ? 57.028  -3.962  119.939 1.00 56.93  ? 218 ARG E NH2 1 
ATOM   12612 N N   . GLN E 1 200 ? 57.427  -0.201  126.511 1.00 72.98  ? 219 GLN E N   1 
ATOM   12613 C CA  . GLN E 1 200 ? 56.637  0.092   127.713 1.00 76.39  ? 219 GLN E CA  1 
ATOM   12614 C C   . GLN E 1 200 ? 55.680  1.275   127.514 1.00 76.09  ? 219 GLN E C   1 
ATOM   12615 O O   . GLN E 1 200 ? 54.588  1.282   128.088 1.00 77.57  ? 219 GLN E O   1 
ATOM   12616 C CB  . GLN E 1 200 ? 57.567  0.347   128.911 1.00 79.68  ? 219 GLN E CB  1 
ATOM   12617 N N   . LYS E 1 201 ? 56.037  2.263   126.701 1.00 74.33  ? 220 LYS E N   1 
ATOM   12618 C CA  . LYS E 1 201 ? 55.196  3.447   126.559 1.00 74.36  ? 220 LYS E CA  1 
ATOM   12619 C C   . LYS E 1 201 ? 54.249  3.405   125.354 1.00 71.59  ? 220 LYS E C   1 
ATOM   12620 O O   . LYS E 1 201 ? 53.370  4.265   125.258 1.00 72.15  ? 220 LYS E O   1 
ATOM   12621 C CB  . LYS E 1 201 ? 56.066  4.719   126.467 1.00 73.97  ? 220 LYS E CB  1 
ATOM   12622 N N   . ILE E 1 202 ? 54.387  2.449   124.433 1.00 71.43  ? 221 ILE E N   1 
ATOM   12623 C CA  . ILE E 1 202 ? 53.459  2.342   123.313 1.00 69.21  ? 221 ILE E CA  1 
ATOM   12624 C C   . ILE E 1 202 ? 52.559  1.121   123.414 1.00 69.69  ? 221 ILE E C   1 
ATOM   12625 O O   . ILE E 1 202 ? 51.509  1.094   122.753 1.00 68.89  ? 221 ILE E O   1 
ATOM   12626 C CB  . ILE E 1 202 ? 54.180  2.319   121.953 1.00 65.82  ? 221 ILE E CB  1 
ATOM   12627 C CG1 . ILE E 1 202 ? 55.159  1.136   121.864 1.00 64.60  ? 221 ILE E CG1 1 
ATOM   12628 C CG2 . ILE E 1 202 ? 54.959  3.607   121.736 1.00 65.89  ? 221 ILE E CG2 1 
ATOM   12629 C CD1 . ILE E 1 202 ? 55.164  0.401   120.521 1.00 61.62  ? 221 ILE E CD1 1 
ATOM   12630 N N   . GLY E 1 203 ? 52.929  0.114   124.197 1.00 67.60  ? 222 GLY E N   1 
ATOM   12631 C CA  . GLY E 1 203 ? 52.086  -1.043  124.400 1.00 68.33  ? 222 GLY E CA  1 
ATOM   12632 C C   . GLY E 1 203 ? 52.415  -2.195  123.464 1.00 65.49  ? 222 GLY E C   1 
ATOM   12633 O O   . GLY E 1 203 ? 53.237  -2.097  122.542 1.00 63.52  ? 222 GLY E O   1 
ATOM   12634 N N   . ASP E 1 204 ? 51.728  -3.317  123.712 1.00 65.75  ? 223 ASP E N   1 
ATOM   12635 C CA  . ASP E 1 204 ? 52.009  -4.555  122.994 1.00 63.84  ? 223 ASP E CA  1 
ATOM   12636 C C   . ASP E 1 204 ? 51.304  -4.615  121.652 1.00 62.19  ? 223 ASP E C   1 
ATOM   12637 O O   . ASP E 1 204 ? 51.742  -5.360  120.777 1.00 61.66  ? 223 ASP E O   1 
ATOM   12638 C CB  . ASP E 1 204 ? 51.607  -5.745  123.863 1.00 66.98  ? 223 ASP E CB  1 
ATOM   12639 C CG  . ASP E 1 204 ? 52.494  -5.879  125.106 1.00 70.36  ? 223 ASP E CG  1 
ATOM   12640 O OD1 . ASP E 1 204 ? 53.492  -5.117  125.208 1.00 73.81  ? 223 ASP E OD1 1 
ATOM   12641 O OD2 . ASP E 1 204 ? 52.179  -6.726  125.984 1.00 70.71  ? 223 ASP E OD2 1 
ATOM   12642 N N   . ASP E 1 205 ? 50.267  -3.818  121.452 1.00 64.47  ? 224 ASP E N   1 
ATOM   12643 C CA  . ASP E 1 205 ? 49.519  -3.843  120.203 1.00 63.08  ? 224 ASP E CA  1 
ATOM   12644 C C   . ASP E 1 205 ? 50.099  -2.927  119.130 1.00 60.82  ? 224 ASP E C   1 
ATOM   12645 O O   . ASP E 1 205 ? 49.565  -2.903  118.012 1.00 60.14  ? 224 ASP E O   1 
ATOM   12646 C CB  . ASP E 1 205 ? 48.051  -3.467  120.451 1.00 65.01  ? 224 ASP E CB  1 
ATOM   12647 C CG  . ASP E 1 205 ? 47.875  -2.050  120.985 1.00 66.92  ? 224 ASP E CG  1 
ATOM   12648 O OD1 . ASP E 1 205 ? 48.850  -1.488  121.536 1.00 67.12  ? 224 ASP E OD1 1 
ATOM   12649 O OD2 . ASP E 1 205 ? 46.745  -1.514  120.871 1.00 69.70  ? 224 ASP E OD2 1 
ATOM   12650 N N   . LYS E 1 206 ? 51.175  -2.200  119.438 1.00 60.18  ? 225 LYS E N   1 
ATOM   12651 C CA  . LYS E 1 206 ? 51.855  -1.305  118.509 1.00 58.70  ? 225 LYS E CA  1 
ATOM   12652 C C   . LYS E 1 206 ? 53.130  -1.963  117.983 1.00 58.41  ? 225 LYS E C   1 
ATOM   12653 O O   . LYS E 1 206 ? 53.652  -2.917  118.560 1.00 59.87  ? 225 LYS E O   1 
ATOM   12654 C CB  . LYS E 1 206 ? 52.188  0.015   119.198 1.00 59.66  ? 225 LYS E CB  1 
ATOM   12655 C CG  . LYS E 1 206 ? 50.978  0.735   119.766 1.00 61.17  ? 225 LYS E CG  1 
ATOM   12656 C CD  . LYS E 1 206 ? 50.095  1.249   118.657 1.00 60.27  ? 225 LYS E CD  1 
ATOM   12657 C CE  . LYS E 1 206 ? 48.940  2.029   119.232 1.00 62.33  ? 225 LYS E CE  1 
ATOM   12658 N NZ  . LYS E 1 206 ? 48.135  2.675   118.163 1.00 61.95  ? 225 LYS E NZ  1 
ATOM   12659 N N   . LEU E 1 207 ? 53.627  -1.434  116.870 1.00 53.97  ? 226 LEU E N   1 
ATOM   12660 C CA  . LEU E 1 207 ? 54.753  -2.020  116.162 1.00 53.42  ? 226 LEU E CA  1 
ATOM   12661 C C   . LEU E 1 207 ? 56.017  -1.229  116.439 1.00 53.30  ? 226 LEU E C   1 
ATOM   12662 O O   . LEU E 1 207 ? 55.992  0.003   116.508 1.00 52.87  ? 226 LEU E O   1 
ATOM   12663 C CB  . LEU E 1 207 ? 54.469  -2.058  114.657 1.00 52.05  ? 226 LEU E CB  1 
ATOM   12664 C CG  . LEU E 1 207 ? 53.413  -3.105  114.264 1.00 52.44  ? 226 LEU E CG  1 
ATOM   12665 C CD1 . LEU E 1 207 ? 52.673  -2.805  112.972 1.00 51.37  ? 226 LEU E CD1 1 
ATOM   12666 C CD2 . LEU E 1 207 ? 54.071  -4.515  114.193 1.00 53.38  ? 226 LEU E CD2 1 
ATOM   12667 N N   . ILE E 1 208 ? 57.124  -1.942  116.603 1.00 51.76  ? 227 ILE E N   1 
ATOM   12668 C CA  . ILE E 1 208 ? 58.448  -1.337  116.626 1.00 51.70  ? 227 ILE E CA  1 
ATOM   12669 C C   . ILE E 1 208 ? 59.232  -1.869  115.425 1.00 51.09  ? 227 ILE E C   1 
ATOM   12670 O O   . ILE E 1 208 ? 59.587  -3.058  115.373 1.00 52.00  ? 227 ILE E O   1 
ATOM   12671 C CB  . ILE E 1 208 ? 59.201  -1.612  117.932 1.00 53.48  ? 227 ILE E CB  1 
ATOM   12672 C CG1 . ILE E 1 208 ? 58.499  -0.947  119.117 1.00 54.19  ? 227 ILE E CG1 1 
ATOM   12673 C CG2 . ILE E 1 208 ? 60.619  -1.096  117.800 1.00 53.79  ? 227 ILE E CG2 1 
ATOM   12674 C CD1 . ILE E 1 208 ? 59.177  -1.196  120.478 1.00 55.83  ? 227 ILE E CD1 1 
ATOM   12675 N N   . VAL E 1 209 ? 59.494  -0.997  114.468 1.00 48.84  ? 228 VAL E N   1 
ATOM   12676 C CA  . VAL E 1 209 ? 60.365  -1.274  113.336 1.00 48.34  ? 228 VAL E CA  1 
ATOM   12677 C C   . VAL E 1 209 ? 61.693  -0.618  113.639 1.00 48.73  ? 228 VAL E C   1 
ATOM   12678 O O   . VAL E 1 209 ? 61.731  0.506   114.157 1.00 48.75  ? 228 VAL E O   1 
ATOM   12679 C CB  . VAL E 1 209 ? 59.775  -0.716  112.026 1.00 46.86  ? 228 VAL E CB  1 
ATOM   12680 C CG1 . VAL E 1 209 ? 60.531  -1.271  110.858 1.00 46.42  ? 228 VAL E CG1 1 
ATOM   12681 C CG2 . VAL E 1 209 ? 58.303  -1.046  111.893 1.00 46.71  ? 228 VAL E CG2 1 
ATOM   12682 N N   . TYR E 1 210 ? 62.794  -1.293  113.338 1.00 47.33  ? 229 TYR E N   1 
ATOM   12683 C CA  . TYR E 1 210 ? 64.081  -0.650  113.552 1.00 47.62  ? 229 TYR E CA  1 
ATOM   12684 C C   . TYR E 1 210 ? 64.997  -0.976  112.390 1.00 47.37  ? 229 TYR E C   1 
ATOM   12685 O O   . TYR E 1 210 ? 64.804  -1.952  111.669 1.00 47.85  ? 229 TYR E O   1 
ATOM   12686 C CB  . TYR E 1 210 ? 64.744  -1.048  114.893 1.00 49.33  ? 229 TYR E CB  1 
ATOM   12687 C CG  . TYR E 1 210 ? 65.523  -2.330  114.830 1.00 50.22  ? 229 TYR E CG  1 
ATOM   12688 C CD1 . TYR E 1 210 ? 64.893  -3.563  115.045 1.00 51.14  ? 229 TYR E CD1 1 
ATOM   12689 C CD2 . TYR E 1 210 ? 66.874  -2.328  114.543 1.00 50.62  ? 229 TYR E CD2 1 
ATOM   12690 C CE1 . TYR E 1 210 ? 65.609  -4.771  114.968 1.00 52.26  ? 229 TYR E CE1 1 
ATOM   12691 C CE2 . TYR E 1 210 ? 67.598  -3.521  114.462 1.00 51.68  ? 229 TYR E CE2 1 
ATOM   12692 C CZ  . TYR E 1 210 ? 66.964  -4.741  114.666 1.00 52.55  ? 229 TYR E CZ  1 
ATOM   12693 O OH  . TYR E 1 210 ? 67.706  -5.913  114.591 1.00 53.85  ? 229 TYR E OH  1 
ATOM   12694 N N   . ASN E 1 211 ? 65.985  -0.116  112.215 1.00 47.68  ? 230 ASN E N   1 
ATOM   12695 C CA  . ASN E 1 211 ? 67.044  -0.264  111.233 1.00 47.32  ? 230 ASN E CA  1 
ATOM   12696 C C   . ASN E 1 211 ? 68.337  -0.498  111.994 1.00 48.52  ? 230 ASN E C   1 
ATOM   12697 O O   . ASN E 1 211 ? 68.892  0.437   112.569 1.00 48.97  ? 230 ASN E O   1 
ATOM   12698 C CB  . ASN E 1 211 ? 67.153  0.991   110.386 1.00 46.25  ? 230 ASN E CB  1 
ATOM   12699 C CG  . ASN E 1 211 ? 68.073  0.805   109.230 1.00 45.95  ? 230 ASN E CG  1 
ATOM   12700 O OD1 . ASN E 1 211 ? 68.469  -0.328  108.942 1.00 46.74  ? 230 ASN E OD1 1 
ATOM   12701 N ND2 . ASN E 1 211 ? 68.417  1.907   108.527 1.00 45.41  ? 230 ASN E ND2 1 
ATOM   12702 N N   . GLY E 1 212 ? 68.829  -1.735  112.003 1.00 47.84  ? 231 GLY E N   1 
ATOM   12703 C CA  . GLY E 1 212 ? 68.296  -2.898  111.331 1.00 47.58  ? 231 GLY E CA  1 
ATOM   12704 C C   . GLY E 1 212 ? 69.354  -3.947  111.072 1.00 48.18  ? 231 GLY E C   1 
ATOM   12705 O O   . GLY E 1 212 ? 70.389  -4.001  111.722 1.00 49.58  ? 231 GLY E O   1 
ATOM   12706 N N   . ILE E 1 213 ? 69.082  -4.778  110.122 1.00 48.19  ? 232 ILE E N   1 
ATOM   12707 C CA  . ILE E 1 213 ? 70.007  -5.823  109.709 1.00 48.26  ? 232 ILE E CA  1 
ATOM   12708 C C   . ILE E 1 213 ? 70.981  -5.234  108.701 1.00 47.31  ? 232 ILE E C   1 
ATOM   12709 O O   . ILE E 1 213 ? 70.592  -4.473  107.808 1.00 46.11  ? 232 ILE E O   1 
ATOM   12710 C CB  . ILE E 1 213 ? 69.229  -7.015  109.123 1.00 47.98  ? 232 ILE E CB  1 
ATOM   12711 C CG1 . ILE E 1 213 ? 68.399  -7.644  110.226 1.00 49.64  ? 232 ILE E CG1 1 
ATOM   12712 C CG2 . ILE E 1 213 ? 70.156  -8.032  108.516 1.00 48.05  ? 232 ILE E CG2 1 
ATOM   12713 C CD1 . ILE E 1 213 ? 67.220  -8.419  109.715 1.00 49.42  ? 232 ILE E CD1 1 
ATOM   12714 N N   . ARG E 1 214 ? 72.252  -5.589  108.842 1.00 46.79  ? 233 ARG E N   1 
ATOM   12715 C CA  . ARG E 1 214 ? 73.312  -5.000  108.031 1.00 46.60  ? 233 ARG E CA  1 
ATOM   12716 C C   . ARG E 1 214 ? 74.467  -5.991  107.957 1.00 47.38  ? 233 ARG E C   1 
ATOM   12717 O O   . ARG E 1 214 ? 74.893  -6.531  108.978 1.00 49.01  ? 233 ARG E O   1 
ATOM   12718 C CB  . ARG E 1 214 ? 73.772  -3.650  108.624 1.00 47.54  ? 233 ARG E CB  1 
ATOM   12719 C CG  . ARG E 1 214 ? 74.941  -2.981  107.906 1.00 48.08  ? 233 ARG E CG  1 
ATOM   12720 C CD  . ARG E 1 214 ? 74.530  -2.410  106.561 1.00 46.61  ? 233 ARG E CD  1 
ATOM   12721 N NE  . ARG E 1 214 ? 73.318  -1.611  106.689 1.00 45.72  ? 233 ARG E NE  1 
ATOM   12722 C CZ  . ARG E 1 214 ? 73.275  -0.399  107.216 1.00 46.25  ? 233 ARG E CZ  1 
ATOM   12723 N NH1 . ARG E 1 214 ? 74.375  0.205   107.630 1.00 47.28  ? 233 ARG E NH1 1 
ATOM   12724 N NH2 . ARG E 1 214 ? 72.100  0.207   107.349 1.00 45.84  ? 233 ARG E NH2 1 
ATOM   12725 N N   . SER E 1 215 ? 74.970  -6.225  106.751 1.00 47.33  ? 234 SER E N   1 
ATOM   12726 C CA  . SER E 1 215 ? 76.060  -7.165  106.527 1.00 48.06  ? 234 SER E CA  1 
ATOM   12727 C C   . SER E 1 215 ? 77.123  -6.446  105.718 1.00 48.23  ? 234 SER E C   1 
ATOM   12728 O O   . SER E 1 215 ? 76.928  -6.152  104.538 1.00 47.20  ? 234 SER E O   1 
ATOM   12729 C CB  . SER E 1 215 ? 75.571  -8.425  105.807 1.00 47.62  ? 234 SER E CB  1 
ATOM   12730 O OG  . SER E 1 215 ? 74.524  -9.038  106.548 1.00 48.14  ? 234 SER E OG  1 
ATOM   12731 N N   . THR E 1 216 ? 78.244  -6.149  106.331 1.00 50.89  ? 235 THR E N   1 
ATOM   12732 C CA  . THR E 1 216 ? 79.364  -5.588  105.594 1.00 51.59  ? 235 THR E CA  1 
ATOM   12733 C C   . THR E 1 216 ? 80.608  -6.410  105.864 1.00 53.65  ? 235 THR E C   1 
ATOM   12734 O O   . THR E 1 216 ? 80.691  -7.129  106.865 1.00 55.25  ? 235 THR E O   1 
ATOM   12735 C CB  . THR E 1 216 ? 79.587  -4.113  105.955 1.00 52.08  ? 235 THR E CB  1 
ATOM   12736 O OG1 . THR E 1 216 ? 80.301  -3.999  107.199 1.00 54.34  ? 235 THR E OG1 1 
ATOM   12737 C CG2 . THR E 1 216 ? 78.240  -3.386  106.065 1.00 51.08  ? 235 THR E CG2 1 
ATOM   12738 N N   . PRO E 1 217 ? 81.593  -6.337  104.975 1.00 53.99  ? 236 PRO E N   1 
ATOM   12739 C CA  . PRO E 1 217 ? 82.843  -7.070  105.219 1.00 56.37  ? 236 PRO E CA  1 
ATOM   12740 C C   . PRO E 1 217 ? 83.385  -6.851  106.601 1.00 59.23  ? 236 PRO E C   1 
ATOM   12741 O O   . PRO E 1 217 ? 83.970  -7.776  107.178 1.00 61.39  ? 236 PRO E O   1 
ATOM   12742 C CB  . PRO E 1 217 ? 83.788  -6.511  104.149 1.00 56.16  ? 236 PRO E CB  1 
ATOM   12743 C CG  . PRO E 1 217 ? 82.849  -6.039  103.034 1.00 54.22  ? 236 PRO E CG  1 
ATOM   12744 C CD  . PRO E 1 217 ? 81.656  -5.497  103.763 1.00 53.07  ? 236 PRO E CD  1 
ATOM   12745 N N   . ASP E 1 218 ? 83.209  -5.656  107.166 1.00 57.78  ? 237 ASP E N   1 
ATOM   12746 C CA  . ASP E 1 218 ? 83.827  -5.309  108.449 1.00 60.63  ? 237 ASP E CA  1 
ATOM   12747 C C   . ASP E 1 218 ? 82.900  -5.520  109.646 1.00 61.15  ? 237 ASP E C   1 
ATOM   12748 O O   . ASP E 1 218 ? 83.353  -5.942  110.707 1.00 63.32  ? 237 ASP E O   1 
ATOM   12749 C CB  . ASP E 1 218 ? 84.307  -3.854  108.416 1.00 61.69  ? 237 ASP E CB  1 
ATOM   12750 C CG  . ASP E 1 218 ? 85.791  -3.739  108.051 1.00 63.87  ? 237 ASP E CG  1 
ATOM   12751 O OD1 . ASP E 1 218 ? 86.663  -4.137  108.879 1.00 65.92  ? 237 ASP E OD1 1 
ATOM   12752 O OD2 . ASP E 1 218 ? 86.079  -3.241  106.933 1.00 63.77  ? 237 ASP E OD2 1 
ATOM   12753 N N   . TRP E 1 219 ? 81.601  -5.267  109.500 1.00 58.88  ? 238 TRP E N   1 
ATOM   12754 C CA  . TRP E 1 219 ? 80.703  -5.148  110.644 1.00 58.70  ? 238 TRP E CA  1 
ATOM   12755 C C   . TRP E 1 219 ? 79.332  -5.699  110.274 1.00 56.70  ? 238 TRP E C   1 
ATOM   12756 O O   . TRP E 1 219 ? 78.809  -5.389  109.200 1.00 55.16  ? 238 TRP E O   1 
ATOM   12757 C CB  . TRP E 1 219 ? 80.593  -3.674  111.065 1.00 58.92  ? 238 TRP E CB  1 
ATOM   12758 C CG  . TRP E 1 219 ? 79.807  -3.448  112.302 1.00 59.56  ? 238 TRP E CG  1 
ATOM   12759 C CD1 . TRP E 1 219 ? 80.287  -3.406  113.574 1.00 61.41  ? 238 TRP E CD1 1 
ATOM   12760 C CD2 . TRP E 1 219 ? 78.397  -3.222  112.393 1.00 58.36  ? 238 TRP E CD2 1 
ATOM   12761 N NE1 . TRP E 1 219 ? 79.260  -3.169  114.455 1.00 61.44  ? 238 TRP E NE1 1 
ATOM   12762 C CE2 . TRP E 1 219 ? 78.090  -3.051  113.753 1.00 59.45  ? 238 TRP E CE2 1 
ATOM   12763 C CE3 . TRP E 1 219 ? 77.364  -3.148  111.457 1.00 56.36  ? 238 TRP E CE3 1 
ATOM   12764 C CZ2 . TRP E 1 219 ? 76.796  -2.815  114.203 1.00 58.60  ? 238 TRP E CZ2 1 
ATOM   12765 C CZ3 . TRP E 1 219 ? 76.067  -2.913  111.911 1.00 55.72  ? 238 TRP E CZ3 1 
ATOM   12766 C CH2 . TRP E 1 219 ? 75.797  -2.763  113.271 1.00 56.92  ? 238 TRP E CH2 1 
ATOM   12767 N N   . SER E 1 220 ? 78.749  -6.516  111.149 1.00 56.14  ? 239 SER E N   1 
ATOM   12768 C CA  . SER E 1 220 ? 77.502  -7.190  110.823 1.00 54.48  ? 239 SER E CA  1 
ATOM   12769 C C   . SER E 1 220 ? 76.606  -7.260  112.047 1.00 54.28  ? 239 SER E C   1 
ATOM   12770 O O   . SER E 1 220 ? 77.071  -7.408  113.175 1.00 56.52  ? 239 SER E O   1 
ATOM   12771 C CB  . SER E 1 220 ? 77.764  -8.599  110.279 1.00 54.92  ? 239 SER E CB  1 
ATOM   12772 O OG  . SER E 1 220 ? 78.487  -8.540  109.058 1.00 54.73  ? 239 SER E OG  1 
ATOM   12773 N N   . ALA E 1 221 ? 75.312  -7.156  111.810 1.00 53.58  ? 240 ALA E N   1 
ATOM   12774 C CA  . ALA E 1 221 ? 74.340  -7.243  112.882 1.00 53.61  ? 240 ALA E CA  1 
ATOM   12775 C C   . ALA E 1 221 ? 73.130  -7.987  112.357 1.00 52.06  ? 240 ALA E C   1 
ATOM   12776 O O   . ALA E 1 221 ? 72.570  -7.610  111.321 1.00 50.55  ? 240 ALA E O   1 
ATOM   12777 C CB  . ALA E 1 221 ? 73.930  -5.854  113.382 1.00 53.98  ? 240 ALA E CB  1 
ATOM   12778 N N   . GLY E 1 222 ? 72.733  -9.032  113.066 1.00 53.05  ? 241 GLY E N   1 
ATOM   12779 C CA  . GLY E 1 222 ? 71.528  -9.747  112.717 1.00 52.24  ? 241 GLY E CA  1 
ATOM   12780 C C   . GLY E 1 222 ? 70.301  -9.090  113.313 1.00 52.27  ? 241 GLY E C   1 
ATOM   12781 O O   . GLY E 1 222 ? 70.330  -7.955  113.794 1.00 52.76  ? 241 GLY E O   1 
ATOM   12782 N N   . PHE E 1 223 ? 69.189  -9.822  113.267 1.00 54.02  ? 242 PHE E N   1 
ATOM   12783 C CA  . PHE E 1 223 ? 68.012  -9.350  113.980 1.00 54.01  ? 242 PHE E CA  1 
ATOM   12784 C C   . PHE E 1 223 ? 68.296  -9.409  115.470 1.00 55.72  ? 242 PHE E C   1 
ATOM   12785 O O   . PHE E 1 223 ? 68.795  -10.422 115.976 1.00 57.62  ? 242 PHE E O   1 
ATOM   12786 C CB  . PHE E 1 223 ? 66.772  -10.149 113.651 1.00 53.73  ? 242 PHE E CB  1 
ATOM   12787 C CG  . PHE E 1 223 ? 65.489  -9.384  113.894 1.00 53.18  ? 242 PHE E CG  1 
ATOM   12788 C CD1 . PHE E 1 223 ? 65.142  -8.955  115.168 1.00 54.59  ? 242 PHE E CD1 1 
ATOM   12789 C CD2 . PHE E 1 223 ? 64.632  -9.102  112.849 1.00 52.20  ? 242 PHE E CD2 1 
ATOM   12790 C CE1 . PHE E 1 223 ? 63.955  -8.265  115.396 1.00 54.54  ? 242 PHE E CE1 1 
ATOM   12791 C CE2 . PHE E 1 223 ? 63.456  -8.424  113.081 1.00 52.27  ? 242 PHE E CE2 1 
ATOM   12792 C CZ  . PHE E 1 223 ? 63.123  -7.997  114.367 1.00 53.20  ? 242 PHE E CZ  1 
ATOM   12793 N N   . ASP E 1 224 ? 67.982  -8.324  116.166 1.00 59.89  ? 243 ASP E N   1 
ATOM   12794 C CA  . ASP E 1 224 ? 68.408  -8.135  117.545 1.00 61.72  ? 243 ASP E CA  1 
ATOM   12795 C C   . ASP E 1 224 ? 67.300  -7.468  118.345 1.00 61.17  ? 243 ASP E C   1 
ATOM   12796 O O   . ASP E 1 224 ? 66.377  -6.870  117.802 1.00 60.27  ? 243 ASP E O   1 
ATOM   12797 C CB  . ASP E 1 224 ? 69.697  -7.312  117.574 1.00 63.44  ? 243 ASP E CB  1 
ATOM   12798 C CG  . ASP E 1 224 ? 70.276  -7.214  118.939 1.00 66.54  ? 243 ASP E CG  1 
ATOM   12799 O OD1 . ASP E 1 224 ? 70.427  -8.267  119.607 1.00 68.15  ? 243 ASP E OD1 1 
ATOM   12800 O OD2 . ASP E 1 224 ? 70.580  -6.107  119.372 1.00 67.36  ? 243 ASP E OD2 1 
ATOM   12801 N N   . PHE E 1 225 ? 67.366  -7.622  119.658 1.00 65.42  ? 244 PHE E N   1 
ATOM   12802 C CA  . PHE E 1 225 ? 66.387  -6.995  120.549 1.00 65.61  ? 244 PHE E CA  1 
ATOM   12803 C C   . PHE E 1 225 ? 64.996  -7.627  120.423 1.00 65.13  ? 244 PHE E C   1 
ATOM   12804 O O   . PHE E 1 225 ? 63.984  -6.986  120.723 1.00 64.76  ? 244 PHE E O   1 
ATOM   12805 C CB  . PHE E 1 225 ? 66.309  -5.479  120.274 1.00 64.78  ? 244 PHE E CB  1 
ATOM   12806 C CG  . PHE E 1 225 ? 67.666  -4.816  120.153 1.00 64.60  ? 244 PHE E CG  1 
ATOM   12807 C CD1 . PHE E 1 225 ? 68.524  -4.752  121.254 1.00 67.06  ? 244 PHE E CD1 1 
ATOM   12808 C CD2 . PHE E 1 225 ? 68.074  -4.251  118.944 1.00 62.35  ? 244 PHE E CD2 1 
ATOM   12809 C CE1 . PHE E 1 225 ? 69.777  -4.121  121.167 1.00 66.80  ? 244 PHE E CE1 1 
ATOM   12810 C CE2 . PHE E 1 225 ? 69.316  -3.629  118.839 1.00 61.93  ? 244 PHE E CE2 1 
ATOM   12811 C CZ  . PHE E 1 225 ? 70.170  -3.539  119.963 1.00 64.17  ? 244 PHE E CZ  1 
ATOM   12812 N N   . ALA E 1 226 ? 64.941  -8.911  120.047 1.00 63.54  ? 245 ALA E N   1 
ATOM   12813 C CA  . ALA E 1 226 ? 63.694  -9.528  119.618 1.00 62.95  ? 245 ALA E CA  1 
ATOM   12814 C C   . ALA E 1 226 ? 62.643  -9.612  120.707 1.00 63.53  ? 245 ALA E C   1 
ATOM   12815 O O   . ALA E 1 226 ? 61.503  -9.987  120.410 1.00 62.79  ? 245 ALA E O   1 
ATOM   12816 C CB  . ALA E 1 226 ? 63.956  -10.935 119.084 1.00 63.34  ? 245 ALA E CB  1 
ATOM   12817 N N   . GLU E 1 227 ? 62.976  -9.292  121.950 1.00 64.07  ? 246 GLU E N   1 
ATOM   12818 C CA  . GLU E 1 227 ? 61.926  -9.257  122.962 1.00 64.85  ? 246 GLU E CA  1 
ATOM   12819 C C   . GLU E 1 227 ? 61.063  -8.006  122.814 1.00 63.75  ? 246 GLU E C   1 
ATOM   12820 O O   . GLU E 1 227 ? 59.933  -7.979  123.306 1.00 64.42  ? 246 GLU E O   1 
ATOM   12821 C CB  . GLU E 1 227 ? 62.539  -9.357  124.375 1.00 67.58  ? 246 GLU E CB  1 
ATOM   12822 N N   . TYR E 1 228 ? 61.542  -6.981  122.146 1.00 62.91  ? 247 TYR E N   1 
ATOM   12823 C CA  . TYR E 1 228 ? 60.873  -5.692  122.139 1.00 62.23  ? 247 TYR E CA  1 
ATOM   12824 C C   . TYR E 1 228 ? 60.558  -5.173  120.756 1.00 60.40  ? 247 TYR E C   1 
ATOM   12825 O O   . TYR E 1 228 ? 59.566  -4.448  120.595 1.00 60.50  ? 247 TYR E O   1 
ATOM   12826 C CB  . TYR E 1 228 ? 61.766  -4.667  122.869 1.00 62.77  ? 247 TYR E CB  1 
ATOM   12827 C CG  . TYR E 1 228 ? 62.142  -5.119  124.273 1.00 65.06  ? 247 TYR E CG  1 
ATOM   12828 C CD1 . TYR E 1 228 ? 62.882  -6.273  124.497 1.00 66.21  ? 247 TYR E CD1 1 
ATOM   12829 C CD2 . TYR E 1 228 ? 61.723  -4.418  125.363 1.00 66.68  ? 247 TYR E CD2 1 
ATOM   12830 C CE1 . TYR E 1 228 ? 63.184  -6.701  125.753 1.00 68.97  ? 247 TYR E CE1 1 
ATOM   12831 C CE2 . TYR E 1 228 ? 62.013  -4.839  126.618 1.00 70.56  ? 247 TYR E CE2 1 
ATOM   12832 C CZ  . TYR E 1 228 ? 62.773  -5.972  126.827 1.00 71.70  ? 247 TYR E CZ  1 
ATOM   12833 O OH  . TYR E 1 228 ? 63.110  -6.407  128.105 1.00 76.56  ? 247 TYR E OH  1 
ATOM   12834 N N   . THR E 1 229 ? 61.331  -5.556  119.754 1.00 59.08  ? 248 THR E N   1 
ATOM   12835 C CA  . THR E 1 229 ? 61.158  -5.157  118.382 1.00 57.75  ? 248 THR E CA  1 
ATOM   12836 C C   . THR E 1 229 ? 60.290  -6.165  117.646 1.00 56.97  ? 248 THR E C   1 
ATOM   12837 O O   . THR E 1 229 ? 60.307  -7.365  117.928 1.00 57.97  ? 248 THR E O   1 
ATOM   12838 C CB  . THR E 1 229 ? 62.512  -5.079  117.688 1.00 58.02  ? 248 THR E CB  1 
ATOM   12839 O OG1 . THR E 1 229 ? 63.136  -6.370  117.764 1.00 59.07  ? 248 THR E OG1 1 
ATOM   12840 C CG2 . THR E 1 229 ? 63.396  -4.034  118.348 1.00 58.47  ? 248 THR E CG2 1 
ATOM   12841 N N   . ASP E 1 230 ? 59.547  -5.666  116.671 1.00 54.69  ? 249 ASP E N   1 
ATOM   12842 C CA  . ASP E 1 230 ? 58.705  -6.508  115.856 1.00 53.98  ? 249 ASP E CA  1 
ATOM   12843 C C   . ASP E 1 230 ? 59.265  -6.738  114.468 1.00 53.34  ? 249 ASP E C   1 
ATOM   12844 O O   . ASP E 1 230 ? 58.935  -7.761  113.857 1.00 52.76  ? 249 ASP E O   1 
ATOM   12845 C CB  . ASP E 1 230 ? 57.311  -5.879  115.739 1.00 53.69  ? 249 ASP E CB  1 
ATOM   12846 C CG  . ASP E 1 230 ? 56.654  -5.699  117.093 1.00 54.87  ? 249 ASP E CG  1 
ATOM   12847 O OD1 . ASP E 1 230 ? 56.418  -6.708  117.810 1.00 56.10  ? 249 ASP E OD1 1 
ATOM   12848 O OD2 . ASP E 1 230 ? 56.392  -4.537  117.456 1.00 54.78  ? 249 ASP E OD2 1 
ATOM   12849 N N   . ALA E 1 231 ? 60.151  -5.861  113.999 1.00 49.91  ? 250 ALA E N   1 
ATOM   12850 C CA  . ALA E 1 231 ? 60.465  -5.735  112.584 1.00 48.80  ? 250 ALA E CA  1 
ATOM   12851 C C   . ALA E 1 231 ? 61.843  -5.112  112.418 1.00 48.92  ? 250 ALA E C   1 
ATOM   12852 O O   . ALA E 1 231 ? 62.204  -4.199  113.165 1.00 49.43  ? 250 ALA E O   1 
ATOM   12853 C CB  . ALA E 1 231 ? 59.408  -4.868  111.887 1.00 47.87  ? 250 ALA E CB  1 
ATOM   12854 N N   . ALA E 1 232 ? 62.579  -5.573  111.409 1.00 45.91  ? 251 ALA E N   1 
ATOM   12855 C CA  . ALA E 1 232 ? 63.884  -5.020  111.096 1.00 46.09  ? 251 ALA E CA  1 
ATOM   12856 C C   . ALA E 1 232 ? 64.031  -4.753  109.607 1.00 44.47  ? 251 ALA E C   1 
ATOM   12857 O O   . ALA E 1 232 ? 63.657  -5.580  108.786 1.00 43.85  ? 251 ALA E O   1 
ATOM   12858 C CB  . ALA E 1 232 ? 65.010  -5.961  111.525 1.00 47.62  ? 251 ALA E CB  1 
ATOM   12859 N N   . MET E 1 233 ? 64.614  -3.618  109.254 1.00 45.36  ? 252 MET E N   1 
ATOM   12860 C CA  A MET E 1 233 ? 64.913  -3.320  107.858 0.55 43.56  ? 252 MET E CA  1 
ATOM   12861 C CA  B MET E 1 233 ? 64.916  -3.326  107.859 0.45 43.56  ? 252 MET E CA  1 
ATOM   12862 C C   . MET E 1 233 ? 66.290  -3.878  107.498 1.00 43.84  ? 252 MET E C   1 
ATOM   12863 O O   . MET E 1 233 ? 67.225  -3.847  108.318 1.00 45.26  ? 252 MET E O   1 
ATOM   12864 C CB  A MET E 1 233 ? 64.854  -1.803  107.600 0.55 43.10  ? 252 MET E CB  1 
ATOM   12865 C CB  B MET E 1 233 ? 64.888  -1.821  107.571 0.45 43.12  ? 252 MET E CB  1 
ATOM   12866 C CG  A MET E 1 233 ? 65.159  -1.328  106.152 0.55 42.25  ? 252 MET E CG  1 
ATOM   12867 C CG  B MET E 1 233 ? 63.609  -1.098  107.965 0.45 43.54  ? 252 MET E CG  1 
ATOM   12868 S SD  A MET E 1 233 ? 64.795  0.437   105.820 0.55 41.32  ? 252 MET E SD  1 
ATOM   12869 S SD  B MET E 1 233 ? 62.193  -1.229  106.859 0.45 41.15  ? 252 MET E SD  1 
ATOM   12870 C CE  A MET E 1 233 ? 63.278  0.303   104.864 0.55 40.69  ? 252 MET E CE  1 
ATOM   12871 C CE  B MET E 1 233 ? 62.896  -0.767  105.272 0.45 40.49  ? 252 MET E CE  1 
ATOM   12872 N N   . ILE E 1 234 ? 66.385  -4.417  106.280 1.00 41.93  ? 253 ILE E N   1 
ATOM   12873 C CA  . ILE E 1 234 ? 67.649  -4.688  105.604 1.00 41.38  ? 253 ILE E CA  1 
ATOM   12874 C C   . ILE E 1 234 ? 67.770  -3.524  104.618 1.00 40.21  ? 253 ILE E C   1 
ATOM   12875 O O   . ILE E 1 234 ? 67.357  -3.602  103.458 1.00 39.42  ? 253 ILE E O   1 
ATOM   12876 C CB  . ILE E 1 234 ? 67.665  -6.045  104.902 1.00 41.15  ? 253 ILE E CB  1 
ATOM   12877 C CG1 . ILE E 1 234 ? 67.393  -7.218  105.841 1.00 42.66  ? 253 ILE E CG1 1 
ATOM   12878 C CG2 . ILE E 1 234 ? 69.026  -6.304  104.240 1.00 41.48  ? 253 ILE E CG2 1 
ATOM   12879 C CD1 . ILE E 1 234 ? 67.098  -8.581  105.074 1.00 42.35  ? 253 ILE E CD1 1 
ATOM   12880 N N   . GLU E 1 235 ? 68.330  -2.417  105.084 1.00 44.05  ? 254 GLU E N   1 
ATOM   12881 C CA  . GLU E 1 235 ? 68.233  -1.178  104.330 1.00 42.86  ? 254 GLU E CA  1 
ATOM   12882 C C   . GLU E 1 235 ? 69.124  -1.180  103.106 1.00 42.11  ? 254 GLU E C   1 
ATOM   12883 O O   . GLU E 1 235 ? 68.828  -0.482  102.119 1.00 41.24  ? 254 GLU E O   1 
ATOM   12884 C CB  . GLU E 1 235 ? 68.635  0.005   105.198 1.00 43.78  ? 254 GLU E CB  1 
ATOM   12885 C CG  . GLU E 1 235 ? 68.073  1.315   104.691 1.00 43.13  ? 254 GLU E CG  1 
ATOM   12886 C CD  . GLU E 1 235 ? 69.071  2.506   104.691 1.00 43.87  ? 254 GLU E CD  1 
ATOM   12887 O OE1 . GLU E 1 235 ? 69.836  2.690   105.708 1.00 45.15  ? 254 GLU E OE1 1 
ATOM   12888 O OE2 . GLU E 1 235 ? 69.040  3.281   103.671 1.00 43.21  ? 254 GLU E OE2 1 
ATOM   12889 N N   . HIS E 1 236 ? 70.233  -1.912  103.161 1.00 41.80  ? 255 HIS E N   1 
ATOM   12890 C CA  . HIS E 1 236 ? 71.272  -1.820  102.154 1.00 41.44  ? 255 HIS E CA  1 
ATOM   12891 C C   . HIS E 1 236 ? 71.374  -3.054  101.272 1.00 41.33  ? 255 HIS E C   1 
ATOM   12892 O O   . HIS E 1 236 ? 72.435  -3.326  100.729 1.00 41.90  ? 255 HIS E O   1 
ATOM   12893 C CB  . HIS E 1 236 ? 72.618  -1.598  102.813 1.00 42.88  ? 255 HIS E CB  1 
ATOM   12894 C CG  . HIS E 1 236 ? 72.813  -0.217  103.349 1.00 43.37  ? 255 HIS E CG  1 
ATOM   12895 N ND1 . HIS E 1 236 ? 71.839  0.759   103.278 1.00 42.56  ? 255 HIS E ND1 1 
ATOM   12896 C CD2 . HIS E 1 236 ? 73.876  0.352   103.964 1.00 44.85  ? 255 HIS E CD2 1 
ATOM   12897 C CE1 . HIS E 1 236 ? 72.298  1.868   103.826 1.00 43.35  ? 255 HIS E CE1 1 
ATOM   12898 N NE2 . HIS E 1 236 ? 73.532  1.651   104.237 1.00 45.05  ? 255 HIS E NE2 1 
ATOM   12899 N N   . PHE E 1 237 ? 70.286  -3.799  101.100 1.00 40.66  ? 256 PHE E N   1 
ATOM   12900 C CA  . PHE E 1 237 ? 70.429  -5.061  100.401 1.00 40.27  ? 256 PHE E CA  1 
ATOM   12901 C C   . PHE E 1 237 ? 71.131  -4.838  99.073  1.00 39.88  ? 256 PHE E C   1 
ATOM   12902 O O   . PHE E 1 237 ? 70.673  -4.050  98.234  1.00 39.22  ? 256 PHE E O   1 
ATOM   12903 C CB  . PHE E 1 237 ? 69.116  -5.790  100.139 1.00 39.74  ? 256 PHE E CB  1 
ATOM   12904 C CG  . PHE E 1 237 ? 69.360  -7.131  99.518  1.00 39.82  ? 256 PHE E CG  1 
ATOM   12905 C CD1 . PHE E 1 237 ? 69.909  -8.171  100.269 1.00 40.95  ? 256 PHE E CD1 1 
ATOM   12906 C CD2 . PHE E 1 237 ? 69.140  -7.328  98.163  1.00 39.25  ? 256 PHE E CD2 1 
ATOM   12907 C CE1 . PHE E 1 237 ? 70.195  -9.370  99.688  1.00 40.74  ? 256 PHE E CE1 1 
ATOM   12908 C CE2 . PHE E 1 237 ? 69.415  -8.529  97.585  1.00 39.36  ? 256 PHE E CE2 1 
ATOM   12909 C CZ  . PHE E 1 237 ? 69.960  -9.553  98.345  1.00 39.80  ? 256 PHE E CZ  1 
ATOM   12910 N N   . GLY E 1 238 ? 72.251  -5.513  98.902  1.00 40.47  ? 257 GLY E N   1 
ATOM   12911 C CA  . GLY E 1 238 ? 72.939  -5.499  97.637  1.00 40.37  ? 257 GLY E CA  1 
ATOM   12912 C C   . GLY E 1 238 ? 73.495  -4.172  97.175  1.00 40.44  ? 257 GLY E C   1 
ATOM   12913 O O   . GLY E 1 238 ? 73.634  -3.979  95.972  1.00 40.76  ? 257 GLY E O   1 
ATOM   12914 N N   . HIS E 1 239 ? 73.831  -3.250  98.080  1.00 42.26  ? 258 HIS E N   1 
ATOM   12915 C CA  A HIS E 1 239 ? 74.478  -2.004  97.675  0.57 42.69  ? 258 HIS E CA  1 
ATOM   12916 C CA  B HIS E 1 239 ? 74.553  -2.055  97.651  0.43 42.82  ? 258 HIS E CA  1 
ATOM   12917 C C   . HIS E 1 239 ? 75.292  -1.455  98.848  1.00 43.54  ? 258 HIS E C   1 
ATOM   12918 O O   . HIS E 1 239 ? 75.302  -2.022  99.947  1.00 44.36  ? 258 HIS E O   1 
ATOM   12919 C CB  A HIS E 1 239 ? 73.480  -0.965  97.153  0.57 42.11  ? 258 HIS E CB  1 
ATOM   12920 C CB  B HIS E 1 239 ? 73.691  -1.141  96.785  0.43 42.43  ? 258 HIS E CB  1 
ATOM   12921 C CG  A HIS E 1 239 ? 73.227  -1.036  95.665  0.57 41.92  ? 258 HIS E CG  1 
ATOM   12922 C CG  B HIS E 1 239 ? 73.041  -0.005  97.461  0.43 42.00  ? 258 HIS E CG  1 
ATOM   12923 N ND1 A HIS E 1 239 ? 73.761  -0.129  94.770  0.57 42.84  ? 258 HIS E ND1 1 
ATOM   12924 N ND1 B HIS E 1 239 ? 73.015  1.255   96.900  0.43 42.32  ? 258 HIS E ND1 1 
ATOM   12925 C CD2 A HIS E 1 239 ? 72.462  -1.882  94.929  0.57 41.75  ? 258 HIS E CD2 1 
ATOM   12926 C CD2 B HIS E 1 239 ? 72.278  0.050   98.570  0.43 42.04  ? 258 HIS E CD2 1 
ATOM   12927 C CE1 A HIS E 1 239 ? 73.361  -0.434  93.547  0.57 42.99  ? 258 HIS E CE1 1 
ATOM   12928 C CE1 B HIS E 1 239 ? 72.305  2.054   97.670  0.43 42.34  ? 258 HIS E CE1 1 
ATOM   12929 N NE2 A HIS E 1 239 ? 72.574  -1.495  93.616  0.57 42.62  ? 258 HIS E NE2 1 
ATOM   12930 N NE2 B HIS E 1 239 ? 71.844  1.348   98.688  0.43 42.44  ? 258 HIS E NE2 1 
ATOM   12931 N N   . PHE E 1 240 ? 75.983  -0.338  98.598  1.00 45.96  ? 259 PHE E N   1 
ATOM   12932 C CA  . PHE E 1 240 ? 76.944  0.275   99.523  1.00 46.81  ? 259 PHE E CA  1 
ATOM   12933 C C   . PHE E 1 240 ? 77.979  -0.804  99.827  1.00 48.46  ? 259 PHE E C   1 
ATOM   12934 O O   . PHE E 1 240 ? 78.508  -1.439  98.905  1.00 49.43  ? 259 PHE E O   1 
ATOM   12935 C CB  . PHE E 1 240 ? 76.260  0.850   100.748 1.00 47.07  ? 259 PHE E CB  1 
ATOM   12936 C CG  . PHE E 1 240 ? 75.258  1.895   100.407 1.00 46.15  ? 259 PHE E CG  1 
ATOM   12937 C CD1 . PHE E 1 240 ? 73.958  1.783   100.895 1.00 46.47  ? 259 PHE E CD1 1 
ATOM   12938 C CD2 . PHE E 1 240 ? 75.618  3.030   99.634  1.00 45.37  ? 259 PHE E CD2 1 
ATOM   12939 C CE1 . PHE E 1 240 ? 72.992  2.829   100.612 1.00 45.68  ? 259 PHE E CE1 1 
ATOM   12940 C CE2 . PHE E 1 240 ? 74.688  4.027   99.327  1.00 44.63  ? 259 PHE E CE2 1 
ATOM   12941 C CZ  . PHE E 1 240 ? 73.369  3.929   99.808  1.00 44.92  ? 259 PHE E CZ  1 
ATOM   12942 N N   . GLN E 1 241 ? 78.284  -1.078  101.084 1.00 47.46  ? 260 GLN E N   1 
ATOM   12943 C CA  . GLN E 1 241 ? 79.190  -2.159  101.423 1.00 49.21  ? 260 GLN E CA  1 
ATOM   12944 C C   . GLN E 1 241 ? 78.472  -3.491  101.694 1.00 48.72  ? 260 GLN E C   1 
ATOM   12945 O O   . GLN E 1 241 ? 79.060  -4.363  102.326 1.00 49.81  ? 260 GLN E O   1 
ATOM   12946 C CB  . GLN E 1 241 ? 80.044  -1.737  102.626 1.00 51.79  ? 260 GLN E CB  1 
ATOM   12947 C CG  . GLN E 1 241 ? 81.067  -0.635  102.288 1.00 53.78  ? 260 GLN E CG  1 
ATOM   12948 C CD  . GLN E 1 241 ? 82.112  -1.080  101.221 1.00 55.87  ? 260 GLN E CD  1 
ATOM   12949 O OE1 . GLN E 1 241 ? 81.860  -0.993  100.009 1.00 55.45  ? 260 GLN E OE1 1 
ATOM   12950 N NE2 . GLN E 1 241 ? 83.268  -1.578  101.680 1.00 57.97  ? 260 GLN E NE2 1 
ATOM   12951 N N   . SER E 1 242 ? 77.247  -3.683  101.198 1.00 45.76  ? 261 SER E N   1 
ATOM   12952 C CA  . SER E 1 242 ? 76.534  -4.956  101.335 1.00 45.45  ? 261 SER E CA  1 
ATOM   12953 C C   . SER E 1 242 ? 76.303  -5.663  99.997  1.00 44.84  ? 261 SER E C   1 
ATOM   12954 O O   . SER E 1 242 ? 75.484  -6.590  99.922  1.00 44.77  ? 261 SER E O   1 
ATOM   12955 C CB  . SER E 1 242 ? 75.190  -4.757  102.033 1.00 44.93  ? 261 SER E CB  1 
ATOM   12956 O OG  . SER E 1 242 ? 75.382  -4.114  103.267 1.00 45.57  ? 261 SER E OG  1 
ATOM   12957 N N   . ALA E 1 243 ? 77.036  -5.269  98.957  1.00 43.88  ? 262 ALA E N   1 
ATOM   12958 C CA  . ALA E 1 243 ? 76.832  -5.755  97.601  1.00 43.56  ? 262 ALA E CA  1 
ATOM   12959 C C   . ALA E 1 243 ? 77.690  -6.970  97.229  1.00 44.76  ? 262 ALA E C   1 
ATOM   12960 O O   . ALA E 1 243 ? 77.551  -7.493  96.109  1.00 44.76  ? 262 ALA E O   1 
ATOM   12961 C CB  . ALA E 1 243 ? 77.102  -4.636  96.595  1.00 43.63  ? 262 ALA E CB  1 
ATOM   12962 N N   . SER E 1 244 ? 78.565  -7.438  98.111  1.00 41.94  ? 263 SER E N   1 
ATOM   12963 C CA  . SER E 1 244 ? 79.279  -8.675  97.841  1.00 43.07  ? 263 SER E CA  1 
ATOM   12964 C C   . SER E 1 244 ? 78.326  -9.872  97.934  1.00 42.53  ? 263 SER E C   1 
ATOM   12965 O O   . SER E 1 244 ? 77.348  -9.872  98.693  1.00 41.80  ? 263 SER E O   1 
ATOM   12966 C CB  . SER E 1 244 ? 80.440  -8.845  98.819  1.00 44.70  ? 263 SER E CB  1 
ATOM   12967 O OG  . SER E 1 244 ? 80.000  -9.216  100.108 1.00 45.11  ? 263 SER E OG  1 
ATOM   12968 N N   . LYS E 1 245 ? 78.633  -10.916 97.157  1.00 42.61  ? 264 LYS E N   1 
ATOM   12969 C CA  . LYS E 1 245 ? 77.857  -12.149 97.257  1.00 42.32  ? 264 LYS E CA  1 
ATOM   12970 C C   . LYS E 1 245 ? 77.847  -12.676 98.694  1.00 42.85  ? 264 LYS E C   1 
ATOM   12971 O O   . LYS E 1 245 ? 76.799  -13.108 99.198  1.00 41.87  ? 264 LYS E O   1 
ATOM   12972 C CB  . LYS E 1 245 ? 78.407  -13.185 96.281  1.00 43.79  ? 264 LYS E CB  1 
ATOM   12973 C CG  . LYS E 1 245 ? 79.783  -13.688 96.633  1.00 46.26  ? 264 LYS E CG  1 
ATOM   12974 C CD  . LYS E 1 245 ? 80.404  -14.488 95.494  1.00 47.71  ? 264 LYS E CD  1 
ATOM   12975 C CE  . LYS E 1 245 ? 81.904  -14.283 95.405  1.00 50.47  ? 264 LYS E CE  1 
ATOM   12976 N NZ  . LYS E 1 245 ? 82.554  -14.993 96.495  1.00 52.80  ? 264 LYS E NZ  1 
ATOM   12977 N N   . GLU E 1 246 ? 78.997  -12.615 99.381  1.00 45.15  ? 265 GLU E N   1 
ATOM   12978 C CA  . GLU E 1 246 ? 79.068  -12.958 100.802 1.00 46.21  ? 265 GLU E CA  1 
ATOM   12979 C C   . GLU E 1 246 ? 78.012  -12.211 101.625 1.00 44.72  ? 265 GLU E C   1 
ATOM   12980 O O   . GLU E 1 246 ? 77.280  -12.819 102.424 1.00 44.74  ? 265 GLU E O   1 
ATOM   12981 C CB  . GLU E 1 246 ? 80.458  -12.626 101.334 1.00 48.36  ? 265 GLU E CB  1 
ATOM   12982 C CG  . GLU E 1 246 ? 81.598  -13.468 100.786 1.00 50.32  ? 265 GLU E CG  1 
ATOM   12983 C CD  . GLU E 1 246 ? 82.203  -12.937 99.491  1.00 50.49  ? 265 GLU E CD  1 
ATOM   12984 O OE1 . GLU E 1 246 ? 81.787  -11.864 99.006  1.00 48.99  ? 265 GLU E OE1 1 
ATOM   12985 O OE2 . GLU E 1 246 ? 83.133  -13.601 98.967  1.00 52.80  ? 265 GLU E OE2 1 
ATOM   12986 N N   . THR E 1 247 ? 77.919  -10.877 101.442 1.00 46.90  ? 266 THR E N   1 
ATOM   12987 C CA  . THR E 1 247 ? 77.037  -10.088 102.295 1.00 45.98  ? 266 THR E CA  1 
ATOM   12988 C C   . THR E 1 247 ? 75.583  -10.178 101.845 1.00 44.15  ? 266 THR E C   1 
ATOM   12989 O O   . THR E 1 247 ? 74.691  -10.055 102.687 1.00 44.12  ? 266 THR E O   1 
ATOM   12990 C CB  . THR E 1 247 ? 77.482  -8.614  102.392 1.00 46.24  ? 266 THR E CB  1 
ATOM   12991 O OG1 . THR E 1 247 ? 77.821  -8.047  101.113 1.00 45.55  ? 266 THR E OG1 1 
ATOM   12992 C CG2 . THR E 1 247 ? 78.700  -8.496  103.284 1.00 47.95  ? 266 THR E CG2 1 
ATOM   12993 N N   . MET E 1 248 ? 75.305  -10.432 100.550 1.00 44.23  ? 267 MET E N   1 
ATOM   12994 C CA  . MET E 1 248 ? 73.916  -10.647 100.140 1.00 42.68  ? 267 MET E CA  1 
ATOM   12995 C C   . MET E 1 248 ? 73.376  -11.943 100.704 1.00 43.05  ? 267 MET E C   1 
ATOM   12996 O O   . MET E 1 248 ? 72.241  -11.993 101.184 1.00 42.38  ? 267 MET E O   1 
ATOM   12997 C CB  . MET E 1 248 ? 73.791  -10.666 98.624  1.00 41.98  ? 267 MET E CB  1 
ATOM   12998 C CG  . MET E 1 248 ? 74.191  -9.336  98.064  1.00 42.03  ? 267 MET E CG  1 
ATOM   12999 S SD  . MET E 1 248 ? 73.799  -9.146  96.348  1.00 41.47  ? 267 MET E SD  1 
ATOM   13000 C CE  . MET E 1 248 ? 75.125  -10.194 95.709  1.00 43.15  ? 267 MET E CE  1 
ATOM   13001 N N   . LEU E 1 249 ? 74.169  -13.013 100.634 1.00 43.68  ? 268 LEU E N   1 
ATOM   13002 C CA  . LEU E 1 249 ? 73.769  -14.265 101.264 1.00 44.35  ? 268 LEU E CA  1 
ATOM   13003 C C   . LEU E 1 249 ? 73.523  -14.059 102.756 1.00 45.01  ? 268 LEU E C   1 
ATOM   13004 O O   . LEU E 1 249 ? 72.498  -14.491 103.299 1.00 44.99  ? 268 LEU E O   1 
ATOM   13005 C CB  . LEU E 1 249 ? 74.849  -15.319 101.025 1.00 45.83  ? 268 LEU E CB  1 
ATOM   13006 C CG  . LEU E 1 249 ? 74.591  -16.689 101.630 1.00 46.69  ? 268 LEU E CG  1 
ATOM   13007 C CD1 . LEU E 1 249 ? 73.312  -17.222 101.037 1.00 45.08  ? 268 LEU E CD1 1 
ATOM   13008 C CD2 . LEU E 1 249 ? 75.735  -17.568 101.324 1.00 48.51  ? 268 LEU E CD2 1 
ATOM   13009 N N   . ARG E 1 250 ? 74.454  -13.390 103.442 1.00 45.66  ? 269 ARG E N   1 
ATOM   13010 C CA  . ARG E 1 250 ? 74.221  -13.077 104.847 1.00 46.47  ? 269 ARG E CA  1 
ATOM   13011 C C   . ARG E 1 250 ? 72.901  -12.341 105.053 1.00 45.53  ? 269 ARG E C   1 
ATOM   13012 O O   . ARG E 1 250 ? 72.212  -12.566 106.047 1.00 46.17  ? 269 ARG E O   1 
ATOM   13013 C CB  . ARG E 1 250 ? 75.383  -12.268 105.417 1.00 47.91  ? 269 ARG E CB  1 
ATOM   13014 C CG  . ARG E 1 250 ? 75.736  -12.663 106.863 1.00 49.15  ? 269 ARG E CG  1 
ATOM   13015 C CD  . ARG E 1 250 ? 77.255  -12.845 107.046 1.00 51.91  ? 269 ARG E CD  1 
ATOM   13016 N NE  . ARG E 1 250 ? 77.892  -11.533 107.072 1.00 52.20  ? 269 ARG E NE  1 
ATOM   13017 C CZ  . ARG E 1 250 ? 78.963  -11.195 106.365 1.00 52.51  ? 269 ARG E CZ  1 
ATOM   13018 N NH1 . ARG E 1 250 ? 79.625  -12.090 105.631 1.00 53.37  ? 269 ARG E NH1 1 
ATOM   13019 N NH2 . ARG E 1 250 ? 79.390  -9.930  106.403 1.00 51.83  ? 269 ARG E NH2 1 
ATOM   13020 N N   . ASP E 1 251 ? 72.520  -11.464 104.128 1.00 45.64  ? 270 ASP E N   1 
ATOM   13021 C CA  . ASP E 1 251 ? 71.280  -10.724 104.321 1.00 44.80  ? 270 ASP E CA  1 
ATOM   13022 C C   . ASP E 1 251 ? 70.080  -11.649 104.082 1.00 44.00  ? 270 ASP E C   1 
ATOM   13023 O O   . ASP E 1 251 ? 69.167  -11.739 104.912 1.00 44.44  ? 270 ASP E O   1 
ATOM   13024 C CB  . ASP E 1 251 ? 71.237  -9.465  103.402 1.00 43.81  ? 270 ASP E CB  1 
ATOM   13025 C CG  . ASP E 1 251 ? 72.056  -8.217  103.955 1.00 44.53  ? 270 ASP E CG  1 
ATOM   13026 O OD1 . ASP E 1 251 ? 72.028  -7.943  105.200 1.00 44.52  ? 270 ASP E OD1 1 
ATOM   13027 O OD2 . ASP E 1 251 ? 72.695  -7.471  103.116 1.00 45.26  ? 270 ASP E OD2 1 
ATOM   13028 N N   . ILE E 1 252 ? 70.083  -12.381 102.965 1.00 43.52  ? 271 ILE E N   1 
ATOM   13029 C CA  . ILE E 1 252 ? 68.938  -13.232 102.634 1.00 42.72  ? 271 ILE E CA  1 
ATOM   13030 C C   . ILE E 1 252 ? 68.730  -14.304 103.692 1.00 44.42  ? 271 ILE E C   1 
ATOM   13031 O O   . ILE E 1 252 ? 67.600  -14.718 103.961 1.00 44.41  ? 271 ILE E O   1 
ATOM   13032 C CB  . ILE E 1 252 ? 69.123  -13.892 101.257 1.00 41.57  ? 271 ILE E CB  1 
ATOM   13033 C CG1 . ILE E 1 252 ? 69.070  -12.860 100.141 1.00 40.61  ? 271 ILE E CG1 1 
ATOM   13034 C CG2 . ILE E 1 252 ? 68.043  -14.939 101.024 1.00 40.83  ? 271 ILE E CG2 1 
ATOM   13035 C CD1 . ILE E 1 252 ? 69.696  -13.323 98.863  1.00 40.41  ? 271 ILE E CD1 1 
ATOM   13036 N N   . LEU E 1 253 ? 69.815  -14.818 104.265 1.00 42.31  ? 272 LEU E N   1 
ATOM   13037 C CA  . LEU E 1 253 ? 69.687  -15.877 105.254 1.00 43.53  ? 272 LEU E CA  1 
ATOM   13038 C C   . LEU E 1 253 ? 69.211  -15.330 106.589 1.00 44.42  ? 272 LEU E C   1 
ATOM   13039 O O   . LEU E 1 253 ? 68.434  -15.980 107.300 1.00 45.20  ? 272 LEU E O   1 
ATOM   13040 C CB  . LEU E 1 253 ? 71.012  -16.606 105.406 1.00 45.07  ? 272 LEU E CB  1 
ATOM   13041 C CG  . LEU E 1 253 ? 71.358  -17.584 104.290 1.00 44.73  ? 272 LEU E CG  1 
ATOM   13042 C CD1 . LEU E 1 253 ? 72.779  -18.108 104.503 1.00 46.52  ? 272 LEU E CD1 1 
ATOM   13043 C CD2 . LEU E 1 253 ? 70.398  -18.753 104.258 1.00 44.72  ? 272 LEU E CD2 1 
ATOM   13044 N N   . GLU E 1 254 ? 69.609  -14.120 106.941 1.00 45.48  ? 273 GLU E N   1 
ATOM   13045 C CA  . GLU E 1 254 ? 69.121  -13.616 108.214 1.00 46.83  ? 273 GLU E CA  1 
ATOM   13046 C C   . GLU E 1 254 ? 67.651  -13.248 108.105 1.00 46.07  ? 273 GLU E C   1 
ATOM   13047 O O   . GLU E 1 254 ? 66.939  -13.331 109.116 1.00 47.10  ? 273 GLU E O   1 
ATOM   13048 C CB  . GLU E 1 254 ? 69.981  -12.454 108.681 1.00 47.83  ? 273 GLU E CB  1 
ATOM   13049 C CG  . GLU E 1 254 ? 69.455  -11.752 109.909 1.00 49.21  ? 273 GLU E CG  1 
ATOM   13050 C CD  . GLU E 1 254 ? 69.272  -12.640 111.126 1.00 51.14  ? 273 GLU E CD  1 
ATOM   13051 O OE1 . GLU E 1 254 ? 69.705  -13.853 111.175 1.00 51.58  ? 273 GLU E OE1 1 
ATOM   13052 O OE2 . GLU E 1 254 ? 68.676  -12.061 112.065 1.00 52.15  ? 273 GLU E OE2 1 
ATOM   13053 N N   . MET E 1 255 ? 67.192  -12.884 106.885 1.00 45.13  ? 274 MET E N   1 
ATOM   13054 C CA  . MET E 1 255 ? 65.780  -12.646 106.625 1.00 44.49  ? 274 MET E CA  1 
ATOM   13055 C C   . MET E 1 255 ? 64.976  -13.921 106.785 1.00 44.40  ? 274 MET E C   1 
ATOM   13056 O O   . MET E 1 255 ? 63.942  -13.946 107.471 1.00 45.22  ? 274 MET E O   1 
ATOM   13057 C CB  . MET E 1 255 ? 65.594  -12.115 105.207 1.00 42.60  ? 274 MET E CB  1 
ATOM   13058 C CG  . MET E 1 255 ? 64.128  -11.915 104.892 1.00 41.98  ? 274 MET E CG  1 
ATOM   13059 S SD  . MET E 1 255 ? 63.680  -11.366 103.236 1.00 39.86  ? 274 MET E SD  1 
ATOM   13060 C CE  . MET E 1 255 ? 64.522  -12.543 102.176 1.00 38.50  ? 274 MET E CE  1 
ATOM   13061 N N   . GLN E 1 256 ? 65.415  -14.984 106.105 1.00 43.85  ? 275 GLN E N   1 
ATOM   13062 C CA  . GLN E 1 256 ? 64.791  -16.297 106.229 1.00 44.33  ? 275 GLN E CA  1 
ATOM   13063 C C   . GLN E 1 256 ? 64.694  -16.744 107.674 1.00 46.27  ? 275 GLN E C   1 
ATOM   13064 O O   . GLN E 1 256 ? 63.660  -17.255 108.113 1.00 47.04  ? 275 GLN E O   1 
ATOM   13065 C CB  . GLN E 1 256 ? 65.597  -17.326 105.428 1.00 44.31  ? 275 GLN E CB  1 
ATOM   13066 C CG  . GLN E 1 256 ? 65.035  -18.697 105.445 1.00 44.81  ? 275 GLN E CG  1 
ATOM   13067 C CD  . GLN E 1 256 ? 65.901  -19.675 104.634 1.00 45.05  ? 275 GLN E CD  1 
ATOM   13068 O OE1 . GLN E 1 256 ? 65.437  -20.264 103.642 1.00 44.94  ? 275 GLN E OE1 1 
ATOM   13069 N NE2 . GLN E 1 256 ? 67.168  -19.836 105.046 1.00 46.05  ? 275 GLN E NE2 1 
ATOM   13070 N N   . ARG E 1 257 ? 65.792  -16.580 108.421 1.00 45.34  ? 276 ARG E N   1 
ATOM   13071 C CA  . ARG E 1 257 ? 65.821  -17.030 109.809 1.00 47.24  ? 276 ARG E CA  1 
ATOM   13072 C C   . ARG E 1 257 ? 64.938  -16.156 110.678 1.00 47.66  ? 276 ARG E C   1 
ATOM   13073 O O   . ARG E 1 257 ? 64.178  -16.659 111.506 1.00 48.47  ? 276 ARG E O   1 
ATOM   13074 C CB  . ARG E 1 257 ? 67.256  -17.028 110.343 1.00 48.86  ? 276 ARG E CB  1 
ATOM   13075 C CG  . ARG E 1 257 ? 67.436  -17.627 111.742 1.00 50.80  ? 276 ARG E CG  1 
ATOM   13076 C CD  . ARG E 1 257 ? 68.657  -17.064 112.489 1.00 52.24  ? 276 ARG E CD  1 
ATOM   13077 N NE  . ARG E 1 257 ? 68.481  -15.635 112.717 1.00 52.27  ? 276 ARG E NE  1 
ATOM   13078 C CZ  . ARG E 1 257 ? 67.633  -15.114 113.598 1.00 52.88  ? 276 ARG E CZ  1 
ATOM   13079 N NH1 . ARG E 1 257 ? 66.956  -15.881 114.445 1.00 54.12  ? 276 ARG E NH1 1 
ATOM   13080 N NH2 . ARG E 1 257 ? 67.464  -13.793 113.630 1.00 52.75  ? 276 ARG E NH2 1 
ATOM   13081 N N   . ALA E 1 258 ? 65.001  -14.842 110.489 1.00 48.06  ? 277 ALA E N   1 
ATOM   13082 C CA  . ALA E 1 258 ? 64.257  -13.980 111.389 1.00 48.69  ? 277 ALA E CA  1 
ATOM   13083 C C   . ALA E 1 258 ? 62.761  -14.105 111.167 1.00 47.57  ? 277 ALA E C   1 
ATOM   13084 O O   . ALA E 1 258 ? 61.986  -13.971 112.121 1.00 48.42  ? 277 ALA E O   1 
ATOM   13085 C CB  . ALA E 1 258 ? 64.718  -12.539 111.225 1.00 48.71  ? 277 ALA E CB  1 
ATOM   13086 N N   . ALA E 1 259 ? 62.331  -14.361 109.927 1.00 47.29  ? 278 ALA E N   1 
ATOM   13087 C CA  . ALA E 1 259 ? 60.899  -14.503 109.653 1.00 46.81  ? 278 ALA E CA  1 
ATOM   13088 C C   . ALA E 1 259 ? 60.367  -15.862 110.109 1.00 48.01  ? 278 ALA E C   1 
ATOM   13089 O O   . ALA E 1 259 ? 59.225  -15.957 110.579 1.00 48.83  ? 278 ALA E O   1 
ATOM   13090 C CB  . ALA E 1 259 ? 60.622  -14.295 108.166 1.00 45.24  ? 278 ALA E CB  1 
ATOM   13091 N N   . LYS E 1 260 ? 61.177  -16.918 109.999 1.00 46.84  ? 279 LYS E N   1 
ATOM   13092 C CA  . LYS E 1 260 ? 60.780  -18.201 110.588 1.00 48.38  ? 279 LYS E CA  1 
ATOM   13093 C C   . LYS E 1 260 ? 60.630  -18.104 112.100 1.00 50.07  ? 279 LYS E C   1 
ATOM   13094 O O   . LYS E 1 260 ? 59.759  -18.744 112.680 1.00 51.41  ? 279 LYS E O   1 
ATOM   13095 C CB  . LYS E 1 260 ? 61.786  -19.289 110.240 1.00 49.72  ? 279 LYS E CB  1 
ATOM   13096 C CG  . LYS E 1 260 ? 61.417  -20.045 108.987 1.00 49.39  ? 279 LYS E CG  1 
ATOM   13097 C CD  . LYS E 1 260 ? 62.580  -20.881 108.477 1.00 50.53  ? 279 LYS E CD  1 
ATOM   13098 C CE  . LYS E 1 260 ? 62.601  -20.872 106.959 1.00 49.61  ? 279 LYS E CE  1 
ATOM   13099 N NZ  . LYS E 1 260 ? 61.542  -21.831 106.394 1.00 50.68  ? 279 LYS E NZ  1 
ATOM   13100 N N   . ALA E 1 261 ? 61.451  -17.277 112.745 1.00 49.71  ? 280 ALA E N   1 
ATOM   13101 C CA  . ALA E 1 261 ? 61.341  -16.970 114.168 1.00 51.36  ? 280 ALA E CA  1 
ATOM   13102 C C   . ALA E 1 261 ? 60.189  -16.029 114.500 1.00 51.10  ? 280 ALA E C   1 
ATOM   13103 O O   . ALA E 1 261 ? 60.063  -15.624 115.666 1.00 52.92  ? 280 ALA E O   1 
ATOM   13104 C CB  . ALA E 1 261 ? 62.665  -16.360 114.668 1.00 52.52  ? 280 ALA E CB  1 
ATOM   13105 N N   . GLY E 1 262 ? 59.359  -15.668 113.513 1.00 52.25  ? 281 GLY E N   1 
ATOM   13106 C CA  . GLY E 1 262 ? 58.125  -14.952 113.740 1.00 51.77  ? 281 GLY E CA  1 
ATOM   13107 C C   . GLY E 1 262 ? 58.227  -13.465 113.528 1.00 50.88  ? 281 GLY E C   1 
ATOM   13108 O O   . GLY E 1 262 ? 57.192  -12.784 113.523 1.00 51.43  ? 281 GLY E O   1 
ATOM   13109 N N   . LYS E 1 263 ? 59.444  -12.948 113.358 1.00 51.08  ? 282 LYS E N   1 
ATOM   13110 C CA  . LYS E 1 263 ? 59.634  -11.533 113.147 1.00 50.49  ? 282 LYS E CA  1 
ATOM   13111 C C   . LYS E 1 263 ? 59.135  -11.141 111.765 1.00 48.88  ? 282 LYS E C   1 
ATOM   13112 O O   . LYS E 1 263 ? 58.742  -12.000 110.946 1.00 48.24  ? 282 LYS E O   1 
ATOM   13113 C CB  . LYS E 1 263 ? 61.107  -11.155 113.306 1.00 51.41  ? 282 LYS E CB  1 
ATOM   13114 C CG  . LYS E 1 263 ? 61.634  -11.317 114.730 1.00 53.69  ? 282 LYS E CG  1 
ATOM   13115 C CD  . LYS E 1 263 ? 60.677  -10.647 115.701 1.00 54.04  ? 282 LYS E CD  1 
ATOM   13116 C CE  . LYS E 1 263 ? 61.179  -10.584 117.118 1.00 55.68  ? 282 LYS E CE  1 
ATOM   13117 N NZ  . LYS E 1 263 ? 60.076  -10.055 117.993 1.00 56.35  ? 282 LYS E NZ  1 
ATOM   13118 N N   . ILE E 1 264 ? 59.134  -9.790  111.550 1.00 47.25  ? 283 ILE E N   1 
ATOM   13119 C CA  . ILE E 1 264 ? 58.924  -9.123  110.273 1.00 45.73  ? 283 ILE E CA  1 
ATOM   13120 C C   . ILE E 1 264 ? 60.273  -8.654  109.749 1.00 45.51  ? 283 ILE E C   1 
ATOM   13121 O O   . ILE E 1 264 ? 61.138  -8.207  110.512 1.00 47.01  ? 283 ILE E O   1 
ATOM   13122 C CB  . ILE E 1 264 ? 57.966  -7.928  110.431 1.00 45.64  ? 283 ILE E CB  1 
ATOM   13123 C CG1 . ILE E 1 264 ? 56.553  -8.394  110.765 1.00 45.99  ? 283 ILE E CG1 1 
ATOM   13124 C CG2 . ILE E 1 264 ? 57.931  -7.098  109.147 1.00 44.55  ? 283 ILE E CG2 1 
ATOM   13125 C CD1 . ILE E 1 264 ? 55.703  -7.376  111.410 1.00 46.66  ? 283 ILE E CD1 1 
ATOM   13126 N N   . VAL E 1 265 ? 60.455  -8.737  108.441 1.00 42.72  ? 284 VAL E N   1 
ATOM   13127 C CA  . VAL E 1 265 ? 61.678  -8.294  107.783 1.00 42.60  ? 284 VAL E CA  1 
ATOM   13128 C C   . VAL E 1 265 ? 61.257  -7.452  106.583 1.00 41.10  ? 284 VAL E C   1 
ATOM   13129 O O   . VAL E 1 265 ? 60.420  -7.877  105.787 1.00 39.80  ? 284 VAL E O   1 
ATOM   13130 C CB  . VAL E 1 265 ? 62.551  -9.485  107.328 1.00 43.13  ? 284 VAL E CB  1 
ATOM   13131 C CG1 . VAL E 1 265 ? 63.816  -8.986  106.614 1.00 43.27  ? 284 VAL E CG1 1 
ATOM   13132 C CG2 . VAL E 1 265 ? 62.924  -10.377 108.493 1.00 45.10  ? 284 VAL E CG2 1 
ATOM   13133 N N   . VAL E 1 266 ? 61.802  -6.260  106.471 1.00 39.09  ? 285 VAL E N   1 
ATOM   13134 C CA  . VAL E 1 266 ? 61.601  -5.407  105.314 1.00 37.87  ? 285 VAL E CA  1 
ATOM   13135 C C   . VAL E 1 266 ? 62.916  -5.438  104.588 1.00 37.16  ? 285 VAL E C   1 
ATOM   13136 O O   . VAL E 1 266 ? 63.935  -5.103  105.182 1.00 38.02  ? 285 VAL E O   1 
ATOM   13137 C CB  . VAL E 1 266 ? 61.211  -3.969  105.714 1.00 38.26  ? 285 VAL E CB  1 
ATOM   13138 C CG1 . VAL E 1 266 ? 61.008  -3.106  104.465 1.00 35.64  ? 285 VAL E CG1 1 
ATOM   13139 C CG2 . VAL E 1 266 ? 59.963  -3.925  106.604 1.00 38.83  ? 285 VAL E CG2 1 
ATOM   13140 N N   . LEU E 1 267 ? 62.919  -5.887  103.342 1.00 38.48  ? 286 LEU E N   1 
ATOM   13141 C CA  . LEU E 1 267 ? 64.128  -5.941  102.517 1.00 37.89  ? 286 LEU E CA  1 
ATOM   13142 C C   . LEU E 1 267 ? 64.100  -4.771  101.521 1.00 36.38  ? 286 LEU E C   1 
ATOM   13143 O O   . LEU E 1 267 ? 63.164  -4.646  100.711 1.00 35.02  ? 286 LEU E O   1 
ATOM   13144 C CB  . LEU E 1 267 ? 64.234  -7.281  101.778 1.00 37.81  ? 286 LEU E CB  1 
ATOM   13145 C CG  . LEU E 1 267 ? 65.598  -7.533  101.127 1.00 37.62  ? 286 LEU E CG  1 
ATOM   13146 C CD1 . LEU E 1 267 ? 65.908  -9.023  100.892 1.00 37.89  ? 286 LEU E CD1 1 
ATOM   13147 C CD2 . LEU E 1 267 ? 65.739  -6.801  99.793  1.00 36.65  ? 286 LEU E CD2 1 
ATOM   13148 N N   . LYS E 1 268 ? 65.099  -3.902  101.571 1.00 40.01  ? 287 LYS E N   1 
ATOM   13149 C CA  . LYS E 1 268 ? 65.042  -2.678  100.784 1.00 38.92  ? 287 LYS E CA  1 
ATOM   13150 C C   . LYS E 1 268 ? 65.932  -2.834  99.563  1.00 39.06  ? 287 LYS E C   1 
ATOM   13151 O O   . LYS E 1 268 ? 67.150  -2.798  99.678  1.00 39.82  ? 287 LYS E O   1 
ATOM   13152 C CB  . LYS E 1 268 ? 65.441  -1.477  101.630 1.00 39.48  ? 287 LYS E CB  1 
ATOM   13153 C CG  . LYS E 1 268 ? 65.691  -0.210  100.844 1.00 39.98  ? 287 LYS E CG  1 
ATOM   13154 C CD  . LYS E 1 268 ? 64.446  0.380   100.204 1.00 37.17  ? 287 LYS E CD  1 
ATOM   13155 C CE  . LYS E 1 268 ? 64.758  1.788   99.742  1.00 37.22  ? 287 LYS E CE  1 
ATOM   13156 N NZ  . LYS E 1 268 ? 65.490  1.736   98.410  1.00 35.70  ? 287 LYS E NZ  1 
ATOM   13157 N N   . GLY E 1 269 ? 65.334  -3.011  98.399  1.00 36.42  ? 288 GLY E N   1 
ATOM   13158 C CA  . GLY E 1 269 ? 66.095  -3.166  97.171  1.00 36.03  ? 288 GLY E CA  1 
ATOM   13159 C C   . GLY E 1 269 ? 66.385  -1.836  96.491  1.00 35.50  ? 288 GLY E C   1 
ATOM   13160 O O   . GLY E 1 269 ? 65.649  -0.877  96.640  1.00 34.47  ? 288 GLY E O   1 
ATOM   13161 N N   . TRP E 1 270 ? 67.454  -1.819  95.695  1.00 36.39  ? 289 TRP E N   1 
ATOM   13162 C CA  . TRP E 1 270 ? 68.030  -0.593  95.177  1.00 36.18  ? 289 TRP E CA  1 
ATOM   13163 C C   . TRP E 1 270 ? 68.165  -0.646  93.665  1.00 37.33  ? 289 TRP E C   1 
ATOM   13164 O O   . TRP E 1 270 ? 69.044  -1.320  93.129  1.00 39.24  ? 289 TRP E O   1 
ATOM   13165 C CB  . TRP E 1 270 ? 69.379  -0.314  95.826  1.00 37.97  ? 289 TRP E CB  1 
ATOM   13166 C CG  . TRP E 1 270 ? 69.192  0.167   97.213  1.00 38.78  ? 289 TRP E CG  1 
ATOM   13167 C CD1 . TRP E 1 270 ? 69.136  -0.596  98.324  1.00 39.76  ? 289 TRP E CD1 1 
ATOM   13168 C CD2 . TRP E 1 270 ? 68.965  1.515   97.638  1.00 39.39  ? 289 TRP E CD2 1 
ATOM   13169 N NE1 . TRP E 1 270 ? 68.911  0.183   99.424  1.00 41.25  ? 289 TRP E NE1 1 
ATOM   13170 C CE2 . TRP E 1 270 ? 68.792  1.487   99.029  1.00 40.27  ? 289 TRP E CE2 1 
ATOM   13171 C CE3 . TRP E 1 270 ? 68.886  2.732   96.980  1.00 38.74  ? 289 TRP E CE3 1 
ATOM   13172 C CZ2 . TRP E 1 270 ? 68.577  2.637   99.785  1.00 40.53  ? 289 TRP E CZ2 1 
ATOM   13173 C CZ3 . TRP E 1 270 ? 68.659  3.895   97.743  1.00 38.62  ? 289 TRP E CZ3 1 
ATOM   13174 C CH2 . TRP E 1 270 ? 68.516  3.830   99.127  1.00 39.30  ? 289 TRP E CH2 1 
ATOM   13175 N N   . ALA E 1 271 ? 67.333  0.146   92.986  1.00 36.81  ? 290 ALA E N   1 
ATOM   13176 C CA  . ALA E 1 271 ? 67.514  0.373   91.562  1.00 36.69  ? 290 ALA E CA  1 
ATOM   13177 C C   . ALA E 1 271 ? 68.853  1.019   91.285  1.00 39.84  ? 290 ALA E C   1 
ATOM   13178 O O   . ALA E 1 271 ? 69.399  1.754   92.113  1.00 41.82  ? 290 ALA E O   1 
ATOM   13179 C CB  . ALA E 1 271 ? 66.402  1.252   91.015  1.00 36.09  ? 290 ALA E CB  1 
ATOM   13180 N N   . GLY E 1 272 ? 69.365  0.758   90.105  1.00 37.96  ? 291 GLY E N   1 
ATOM   13181 C CA  . GLY E 1 272 ? 70.608  1.350   89.695  1.00 39.39  ? 291 GLY E CA  1 
ATOM   13182 C C   . GLY E 1 272 ? 71.741  0.354   89.756  1.00 40.38  ? 291 GLY E C   1 
ATOM   13183 O O   . GLY E 1 272 ? 71.663  -0.679  90.424  1.00 40.29  ? 291 GLY E O   1 
ATOM   13184 N N   . PHE E 1 273 ? 72.806  0.663   89.035  1.00 37.46  ? 292 PHE E N   1 
ATOM   13185 C CA  . PHE E 1 273 ? 73.958  -0.199  88.968  1.00 38.07  ? 292 PHE E CA  1 
ATOM   13186 C C   . PHE E 1 273 ? 75.154  0.675   88.653  1.00 39.19  ? 292 PHE E C   1 
ATOM   13187 O O   . PHE E 1 273 ? 75.035  1.880   88.437  1.00 40.64  ? 292 PHE E O   1 
ATOM   13188 C CB  . PHE E 1 273 ? 73.755  -1.318  87.933  1.00 38.70  ? 292 PHE E CB  1 
ATOM   13189 C CG  . PHE E 1 273 ? 73.421  -0.828  86.528  1.00 40.22  ? 292 PHE E CG  1 
ATOM   13190 C CD1 . PHE E 1 273 ? 74.340  -0.101  85.784  1.00 42.62  ? 292 PHE E CD1 1 
ATOM   13191 C CD2 . PHE E 1 273 ? 72.181  -1.110  85.949  1.00 39.67  ? 292 PHE E CD2 1 
ATOM   13192 C CE1 . PHE E 1 273 ? 74.021  0.341   84.482  1.00 43.89  ? 292 PHE E CE1 1 
ATOM   13193 C CE2 . PHE E 1 273 ? 71.869  -0.691  84.655  1.00 41.43  ? 292 PHE E CE2 1 
ATOM   13194 C CZ  . PHE E 1 273 ? 72.785  0.028   83.925  1.00 42.70  ? 292 PHE E CZ  1 
ATOM   13195 N N   . THR E 1 274 ? 76.317  0.060   88.635  1.00 34.94  ? 293 THR E N   1 
ATOM   13196 C CA  . THR E 1 274 ? 77.577  0.734   88.378  1.00 36.81  ? 293 THR E CA  1 
ATOM   13197 C C   . THR E 1 274 ? 78.092  0.327   87.003  1.00 38.73  ? 293 THR E C   1 
ATOM   13198 O O   . THR E 1 274 ? 78.172  -0.861  86.677  1.00 38.74  ? 293 THR E O   1 
ATOM   13199 C CB  . THR E 1 274 ? 78.600  0.408   89.474  1.00 37.34  ? 293 THR E CB  1 
ATOM   13200 O OG1 . THR E 1 274 ? 78.044  0.771   90.756  1.00 35.72  ? 293 THR E OG1 1 
ATOM   13201 C CG2 . THR E 1 274 ? 79.914  1.141   89.210  1.00 40.04  ? 293 THR E CG2 1 
ATOM   13202 N N   . PHE E 1 275 ? 78.422  1.330   86.202  1.00 35.23  ? 294 PHE E N   1 
ATOM   13203 C CA  . PHE E 1 275 ? 78.972  1.127   84.869  1.00 38.25  ? 294 PHE E CA  1 
ATOM   13204 C C   . PHE E 1 275 ? 79.845  2.352   84.646  1.00 41.79  ? 294 PHE E C   1 
ATOM   13205 O O   . PHE E 1 275 ? 79.321  3.471   84.638  1.00 41.86  ? 294 PHE E O   1 
ATOM   13206 C CB  . PHE E 1 275 ? 77.883  0.976   83.814  1.00 37.28  ? 294 PHE E CB  1 
ATOM   13207 C CG  . PHE E 1 275 ? 78.426  0.931   82.408  1.00 40.95  ? 294 PHE E CG  1 
ATOM   13208 C CD1 . PHE E 1 275 ? 78.843  -0.272  81.833  1.00 42.34  ? 294 PHE E CD1 1 
ATOM   13209 C CD2 . PHE E 1 275 ? 78.561  2.094   81.671  1.00 43.54  ? 294 PHE E CD2 1 
ATOM   13210 C CE1 . PHE E 1 275 ? 79.365  -0.281  80.542  1.00 46.17  ? 294 PHE E CE1 1 
ATOM   13211 C CE2 . PHE E 1 275 ? 79.066  2.061   80.404  1.00 47.26  ? 294 PHE E CE2 1 
ATOM   13212 C CZ  . PHE E 1 275 ? 79.463  0.883   79.838  1.00 48.55  ? 294 PHE E CZ  1 
ATOM   13213 N N   . ILE E 1 276 ? 81.168  2.151   84.569  1.00 44.98  ? 295 ILE E N   1 
ATOM   13214 C CA  . ILE E 1 276 ? 82.157  3.232   84.501  1.00 49.19  ? 295 ILE E CA  1 
ATOM   13215 C C   . ILE E 1 276 ? 82.210  4.039   85.811  1.00 48.53  ? 295 ILE E C   1 
ATOM   13216 O O   . ILE E 1 276 ? 83.305  4.323   86.322  1.00 51.41  ? 295 ILE E O   1 
ATOM   13217 C CB  . ILE E 1 276 ? 81.886  4.156   83.297  1.00 51.38  ? 295 ILE E CB  1 
ATOM   13218 C CG1 . ILE E 1 276 ? 82.135  3.397   81.985  1.00 53.63  ? 295 ILE E CG1 1 
ATOM   13219 C CG2 . ILE E 1 276 ? 82.799  5.352   83.369  1.00 55.61  ? 295 ILE E CG2 1 
ATOM   13220 C CD1 . ILE E 1 276 ? 81.677  4.127   80.718  1.00 55.57  ? 295 ILE E CD1 1 
ATOM   13221 N N   . ASP E 1 277 ? 81.037  4.412   86.344  1.00 45.62  ? 296 ASP E N   1 
ATOM   13222 C CA  . ASP E 1 277 ? 80.890  4.972   87.687  1.00 44.53  ? 296 ASP E CA  1 
ATOM   13223 C C   . ASP E 1 277 ? 79.508  4.578   88.218  1.00 40.28  ? 296 ASP E C   1 
ATOM   13224 O O   . ASP E 1 277 ? 78.742  3.870   87.549  1.00 38.29  ? 296 ASP E O   1 
ATOM   13225 C CB  . ASP E 1 277 ? 81.057  6.516   87.718  1.00 47.21  ? 296 ASP E CB  1 
ATOM   13226 C CG  . ASP E 1 277 ? 80.176  7.224   86.677  1.00 47.22  ? 296 ASP E CG  1 
ATOM   13227 O OD1 . ASP E 1 277 ? 78.918  7.078   86.710  1.00 44.06  ? 296 ASP E OD1 1 
ATOM   13228 O OD2 . ASP E 1 277 ? 80.760  7.922   85.807  1.00 50.92  ? 296 ASP E OD2 1 
ATOM   13229 N N   . ASP E 1 278 ? 79.178  5.089   89.416  1.00 44.15  ? 297 ASP E N   1 
ATOM   13230 C CA  . ASP E 1 278 ? 77.923  4.800   90.110  1.00 44.15  ? 297 ASP E CA  1 
ATOM   13231 C C   . ASP E 1 278 ? 76.919  5.963   90.027  1.00 44.15  ? 297 ASP E C   1 
ATOM   13232 O O   . ASP E 1 278 ? 75.955  6.011   90.809  1.00 44.15  ? 297 ASP E O   1 
ATOM   13233 C CB  . ASP E 1 278 ? 78.211  4.417   91.570  1.00 44.15  ? 297 ASP E CB  1 
ATOM   13234 N N   . GLN E 1 279 ? 77.101  6.859   89.061  1.00 47.43  ? 298 GLN E N   1 
ATOM   13235 C CA  . GLN E 1 279 ? 76.285  8.054   88.912  1.00 46.50  ? 298 GLN E CA  1 
ATOM   13236 C C   . GLN E 1 279 ? 75.036  7.834   88.070  1.00 45.90  ? 298 GLN E C   1 
ATOM   13237 O O   . GLN E 1 279 ? 74.408  8.827   87.660  1.00 45.41  ? 298 GLN E O   1 
ATOM   13238 C CB  . GLN E 1 279 ? 77.108  9.187   88.266  1.00 46.89  ? 298 GLN E CB  1 
ATOM   13239 C CG  . GLN E 1 279 ? 78.190  9.697   89.161  1.00 48.14  ? 298 GLN E CG  1 
ATOM   13240 C CD  . GLN E 1 279 ? 77.615  10.534  90.268  1.00 47.97  ? 298 GLN E CD  1 
ATOM   13241 O OE1 . GLN E 1 279 ? 77.433  10.042  91.387  1.00 46.45  ? 298 GLN E OE1 1 
ATOM   13242 N NE2 . GLN E 1 279 ? 77.287  11.829  89.958  1.00 49.51  ? 298 GLN E NE2 1 
ATOM   13243 N N   . ALA E 1 280 ? 74.652  6.582   87.814  1.00 43.75  ? 299 ALA E N   1 
ATOM   13244 C CA  . ALA E 1 280 ? 73.603  6.326   86.832  1.00 43.03  ? 299 ALA E CA  1 
ATOM   13245 C C   . ALA E 1 280 ? 72.258  6.876   87.294  1.00 40.10  ? 299 ALA E C   1 
ATOM   13246 O O   . ALA E 1 280 ? 71.464  7.364   86.481  1.00 41.22  ? 299 ALA E O   1 
ATOM   13247 C CB  . ALA E 1 280 ? 73.491  4.821   86.554  1.00 42.33  ? 299 ALA E CB  1 
ATOM   13248 N N   . MET E 1 281 ? 71.948  6.736   88.574  1.00 40.72  ? 300 MET E N   1 
ATOM   13249 C CA  . MET E 1 281 ? 70.677  7.210   89.099  1.00 40.26  ? 300 MET E CA  1 
ATOM   13250 C C   . MET E 1 281 ? 70.677  8.739   89.392  1.00 40.67  ? 300 MET E C   1 
ATOM   13251 O O   . MET E 1 281 ? 69.747  9.248   90.039  1.00 39.83  ? 300 MET E O   1 
ATOM   13252 C CB  . MET E 1 281 ? 70.337  6.421   90.353  1.00 39.91  ? 300 MET E CB  1 
ATOM   13253 C CG  . MET E 1 281 ? 70.121  4.890   90.146  1.00 39.95  ? 300 MET E CG  1 
ATOM   13254 S SD  . MET E 1 281 ? 69.120  4.465   88.679  1.00 41.33  ? 300 MET E SD  1 
ATOM   13255 C CE  . MET E 1 281 ? 67.509  4.881   89.242  1.00 37.82  ? 300 MET E CE  1 
ATOM   13256 N N   . ARG E 1 282 ? 71.698  9.464   88.948  1.00 36.73  ? 301 ARG E N   1 
ATOM   13257 C CA  . ARG E 1 282 ? 71.733  10.926  89.038  1.00 38.94  ? 301 ARG E CA  1 
ATOM   13258 C C   . ARG E 1 282 ? 71.328  11.564  87.706  1.00 40.71  ? 301 ARG E C   1 
ATOM   13259 O O   . ARG E 1 282 ? 71.333  12.805  87.560  1.00 42.98  ? 301 ARG E O   1 
ATOM   13260 C CB  . ARG E 1 282 ? 73.135  11.386  89.471  1.00 40.86  ? 301 ARG E CB  1 
ATOM   13261 C CG  . ARG E 1 282 ? 73.572  10.831  90.859  1.00 39.75  ? 301 ARG E CG  1 
ATOM   13262 C CD  . ARG E 1 282 ? 73.412  11.838  91.977  1.00 40.66  ? 301 ARG E CD  1 
ATOM   13263 N NE  . ARG E 1 282 ? 74.219  13.063  91.811  1.00 44.81  ? 301 ARG E NE  1 
ATOM   13264 C CZ  . ARG E 1 282 ? 73.910  14.173  92.461  1.00 46.91  ? 301 ARG E CZ  1 
ATOM   13265 N NH1 . ARG E 1 282 ? 72.873  14.201  93.288  1.00 45.12  ? 301 ARG E NH1 1 
ATOM   13266 N NH2 . ARG E 1 282 ? 74.646  15.277  92.283  1.00 51.31  ? 301 ARG E NH2 1 
ATOM   13267 N N   . LYS E 1 283 ? 70.989  10.722  86.750  1.00 38.58  ? 302 LYS E N   1 
ATOM   13268 C CA  . LYS E 1 283 ? 70.638  11.110  85.402  1.00 40.37  ? 302 LYS E CA  1 
ATOM   13269 C C   . LYS E 1 283 ? 69.159  11.472  85.332  1.00 39.90  ? 302 LYS E C   1 
ATOM   13270 O O   . LYS E 1 283 ? 68.403  11.290  86.295  1.00 37.84  ? 302 LYS E O   1 
ATOM   13271 C CB  . LYS E 1 283 ? 70.979  9.958   84.465  1.00 39.56  ? 302 LYS E CB  1 
ATOM   13272 C CG  . LYS E 1 283 ? 72.484  9.667   84.290  1.00 41.10  ? 302 LYS E CG  1 
ATOM   13273 C CD  . LYS E 1 283 ? 73.322  10.882  84.600  1.00 44.62  ? 302 LYS E CD  1 
ATOM   13274 C CE  . LYS E 1 283 ? 74.823  10.655  84.318  1.00 47.40  ? 302 LYS E CE  1 
ATOM   13275 N NZ  . LYS E 1 283 ? 75.561  10.282  85.594  1.00 45.91  ? 302 LYS E NZ  1 
ATOM   13276 N N   . PRO E 1 284 ? 68.711  12.006  84.196  1.00 41.11  ? 303 PRO E N   1 
ATOM   13277 C CA  . PRO E 1 284 ? 67.293  12.350  84.054  1.00 40.99  ? 303 PRO E CA  1 
ATOM   13278 C C   . PRO E 1 284 ? 66.400  11.150  84.287  1.00 36.62  ? 303 PRO E C   1 
ATOM   13279 O O   . PRO E 1 284 ? 66.808  10.007  84.119  1.00 34.06  ? 303 PRO E O   1 
ATOM   13280 C CB  . PRO E 1 284 ? 67.183  12.858  82.608  1.00 44.45  ? 303 PRO E CB  1 
ATOM   13281 C CG  . PRO E 1 284 ? 68.553  13.342  82.311  1.00 47.67  ? 303 PRO E CG  1 
ATOM   13282 C CD  . PRO E 1 284 ? 69.487  12.398  83.011  1.00 44.73  ? 303 PRO E CD  1 
ATOM   13283 N N   . LEU E 1 285 ? 65.145  11.448  84.638  1.00 37.02  ? 304 LEU E N   1 
ATOM   13284 C CA  . LEU E 1 285 ? 64.184  10.448  85.098  1.00 35.31  ? 304 LEU E CA  1 
ATOM   13285 C C   . LEU E 1 285 ? 63.925  9.344   84.074  1.00 35.70  ? 304 LEU E C   1 
ATOM   13286 O O   . LEU E 1 285 ? 63.714  8.189   84.450  1.00 34.64  ? 304 LEU E O   1 
ATOM   13287 C CB  . LEU E 1 285 ? 62.871  11.146  85.436  1.00 34.79  ? 304 LEU E CB  1 
ATOM   13288 C CG  . LEU E 1 285 ? 61.625  10.351  85.754  1.00 33.26  ? 304 LEU E CG  1 
ATOM   13289 C CD1 . LEU E 1 285 ? 61.900  9.379   86.887  1.00 31.62  ? 304 LEU E CD1 1 
ATOM   13290 C CD2 . LEU E 1 285 ? 60.503  11.281  86.158  1.00 33.26  ? 304 LEU E CD2 1 
ATOM   13291 N N   . THR E 1 286 ? 63.893  9.665   82.787  1.00 34.97  ? 305 THR E N   1 
ATOM   13292 C CA  . THR E 1 286 ? 63.708  8.595   81.821  1.00 35.10  ? 305 THR E CA  1 
ATOM   13293 C C   . THR E 1 286 ? 64.887  7.629   81.879  1.00 35.89  ? 305 THR E C   1 
ATOM   13294 O O   . THR E 1 286 ? 64.702  6.410   81.824  1.00 37.02  ? 305 THR E O   1 
ATOM   13295 C CB  . THR E 1 286 ? 63.542  9.144   80.406  1.00 36.99  ? 305 THR E CB  1 
ATOM   13296 O OG1 . THR E 1 286 ? 64.757  9.786   80.044  1.00 38.53  ? 305 THR E OG1 1 
ATOM   13297 C CG2 . THR E 1 286 ? 62.331  10.077  80.312  1.00 37.52  ? 305 THR E CG2 1 
ATOM   13298 N N   . GLN E 1 287 ? 66.108  8.155   82.006  1.00 36.37  ? 306 GLN E N   1 
ATOM   13299 C CA  . GLN E 1 287 ? 67.263  7.277   82.169  1.00 38.26  ? 306 GLN E CA  1 
ATOM   13300 C C   . GLN E 1 287 ? 67.159  6.486   83.480  1.00 36.75  ? 306 GLN E C   1 
ATOM   13301 O O   . GLN E 1 287 ? 67.427  5.281   83.506  1.00 37.07  ? 306 GLN E O   1 
ATOM   13302 C CB  . GLN E 1 287 ? 68.555  8.088   82.077  1.00 37.83  ? 306 GLN E CB  1 
ATOM   13303 N N   . LYS E 1 288 ? 66.707  7.128   84.562  1.00 39.22  ? 307 LYS E N   1 
ATOM   13304 C CA  . LYS E 1 288 ? 66.523  6.395   85.810  1.00 38.57  ? 307 LYS E CA  1 
ATOM   13305 C C   . LYS E 1 288 ? 65.535  5.262   85.630  1.00 39.17  ? 307 LYS E C   1 
ATOM   13306 O O   . LYS E 1 288 ? 65.733  4.151   86.163  1.00 37.93  ? 307 LYS E O   1 
ATOM   13307 C CB  . LYS E 1 288 ? 66.000  7.289   86.934  1.00 36.90  ? 307 LYS E CB  1 
ATOM   13308 C CG  . LYS E 1 288 ? 66.986  8.345   87.453  1.00 37.83  ? 307 LYS E CG  1 
ATOM   13309 C CD  . LYS E 1 288 ? 66.488  8.949   88.788  1.00 36.95  ? 307 LYS E CD  1 
ATOM   13310 C CE  . LYS E 1 288 ? 66.039  10.392  88.636  1.00 35.39  ? 307 LYS E CE  1 
ATOM   13311 N NZ  . LYS E 1 288 ? 67.240  11.188  88.739  1.00 37.65  ? 307 LYS E NZ  1 
ATOM   13312 N N   . ARG E 1 289 ? 64.447  5.522   84.906  1.00 39.29  ? 308 ARG E N   1 
ATOM   13313 C CA  . ARG E 1 289 ? 63.381  4.525   84.829  1.00 38.21  ? 308 ARG E CA  1 
ATOM   13314 C C   . ARG E 1 289 ? 63.806  3.333   83.990  1.00 40.42  ? 308 ARG E C   1 
ATOM   13315 O O   . ARG E 1 289 ? 63.397  2.205   84.260  1.00 40.02  ? 308 ARG E O   1 
ATOM   13316 C CB  . ARG E 1 289 ? 62.120  5.131   84.241  1.00 38.23  ? 308 ARG E CB  1 
ATOM   13317 C CG  . ARG E 1 289 ? 61.320  5.889   85.207  1.00 36.44  ? 308 ARG E CG  1 
ATOM   13318 C CD  . ARG E 1 289 ? 60.171  6.533   84.487  1.00 35.81  ? 308 ARG E CD  1 
ATOM   13319 N NE  . ARG E 1 289 ? 59.230  7.064   85.463  1.00 35.95  ? 308 ARG E NE  1 
ATOM   13320 C CZ  . ARG E 1 289 ? 58.425  8.090   85.243  1.00 34.00  ? 308 ARG E CZ  1 
ATOM   13321 N NH1 . ARG E 1 289 ? 58.460  8.751   84.105  1.00 35.28  ? 308 ARG E NH1 1 
ATOM   13322 N NH2 . ARG E 1 289 ? 57.532  8.421   86.171  1.00 31.83  ? 308 ARG E NH2 1 
ATOM   13323 N N   . ARG E 1 290 ? 64.569  3.573   82.927  1.00 38.70  ? 309 ARG E N   1 
ATOM   13324 C CA  . ARG E 1 290 ? 65.092  2.456   82.150  1.00 40.13  ? 309 ARG E CA  1 
ATOM   13325 C C   . ARG E 1 290 ? 65.948  1.571   83.048  1.00 39.39  ? 309 ARG E C   1 
ATOM   13326 O O   . ARG E 1 290 ? 65.770  0.340   83.098  1.00 39.18  ? 309 ARG E O   1 
ATOM   13327 C CB  . ARG E 1 290 ? 65.883  2.976   80.948  1.00 41.83  ? 309 ARG E CB  1 
ATOM   13328 C CG  . ARG E 1 290 ? 66.876  1.975   80.347  1.00 44.14  ? 309 ARG E CG  1 
ATOM   13329 C CD  . ARG E 1 290 ? 67.755  2.647   79.269  1.00 47.41  ? 309 ARG E CD  1 
ATOM   13330 N NE  . ARG E 1 290 ? 68.973  3.234   79.840  1.00 48.93  ? 309 ARG E NE  1 
ATOM   13331 C CZ  . ARG E 1 290 ? 69.430  4.465   79.587  1.00 50.07  ? 309 ARG E CZ  1 
ATOM   13332 N NH1 . ARG E 1 290 ? 68.818  5.281   78.715  1.00 50.78  ? 309 ARG E NH1 1 
ATOM   13333 N NH2 . ARG E 1 290 ? 70.535  4.886   80.217  1.00 50.06  ? 309 ARG E NH2 1 
ATOM   13334 N N   . VAL E 1 291 ? 66.853  2.211   83.800  1.00 38.87  ? 310 VAL E N   1 
ATOM   13335 C CA  . VAL E 1 291 ? 67.750  1.508   84.708  1.00 38.60  ? 310 VAL E CA  1 
ATOM   13336 C C   . VAL E 1 291 ? 66.961  0.764   85.773  1.00 37.14  ? 310 VAL E C   1 
ATOM   13337 O O   . VAL E 1 291 ? 67.248  -0.400  86.077  1.00 36.80  ? 310 VAL E O   1 
ATOM   13338 C CB  . VAL E 1 291 ? 68.731  2.505   85.348  1.00 38.36  ? 310 VAL E CB  1 
ATOM   13339 C CG1 . VAL E 1 291 ? 69.569  1.830   86.426  1.00 38.34  ? 310 VAL E CG1 1 
ATOM   13340 C CG2 . VAL E 1 291 ? 69.662  3.042   84.302  1.00 39.35  ? 310 VAL E CG2 1 
ATOM   13341 N N   . ALA E 1 292 ? 65.984  1.438   86.387  1.00 37.87  ? 311 ALA E N   1 
ATOM   13342 C CA  . ALA E 1 292 ? 65.181  0.774   87.404  1.00 35.43  ? 311 ALA E CA  1 
ATOM   13343 C C   . ALA E 1 292 ? 64.505  -0.469  86.826  1.00 35.52  ? 311 ALA E C   1 
ATOM   13344 O O   . ALA E 1 292 ? 64.360  -1.482  87.517  1.00 34.34  ? 311 ALA E O   1 
ATOM   13345 C CB  . ALA E 1 292 ? 64.142  1.725   87.996  1.00 33.29  ? 311 ALA E CB  1 
ATOM   13346 N N   . LYS E 1 293 ? 64.096  -0.416  85.558  1.00 35.61  ? 312 LYS E N   1 
ATOM   13347 C CA  . LYS E 1 293 ? 63.392  -1.554  84.970  1.00 34.68  ? 312 LYS E CA  1 
ATOM   13348 C C   . LYS E 1 293 ? 64.360  -2.721  84.780  1.00 35.86  ? 312 LYS E C   1 
ATOM   13349 O O   . LYS E 1 293 ? 64.038  -3.840  85.149  1.00 34.13  ? 312 LYS E O   1 
ATOM   13350 C CB  . LYS E 1 293 ? 62.691  -1.139  83.664  1.00 36.03  ? 312 LYS E CB  1 
ATOM   13351 N N   . ASP E 1 294 ? 65.594  -2.460  84.334  1.00 35.83  ? 313 ASP E N   1 
ATOM   13352 C CA  . ASP E 1 294 ? 66.605  -3.498  84.145  1.00 37.13  ? 313 ASP E CA  1 
ATOM   13353 C C   . ASP E 1 294 ? 67.168  -4.080  85.454  1.00 36.38  ? 313 ASP E C   1 
ATOM   13354 O O   . ASP E 1 294 ? 67.724  -5.195  85.445  1.00 36.88  ? 313 ASP E O   1 
ATOM   13355 C CB  . ASP E 1 294 ? 67.763  -2.905  83.327  1.00 39.86  ? 313 ASP E CB  1 
ATOM   13356 C CG  . ASP E 1 294 ? 67.377  -2.607  81.881  1.00 42.06  ? 313 ASP E CG  1 
ATOM   13357 O OD1 . ASP E 1 294 ? 66.333  -3.130  81.380  1.00 41.92  ? 313 ASP E OD1 1 
ATOM   13358 O OD2 . ASP E 1 294 ? 68.123  -1.831  81.225  1.00 43.64  ? 313 ASP E OD2 1 
ATOM   13359 N N   . SER E 1 295 ? 67.066  -3.344  86.556  1.00 35.62  ? 314 SER E N   1 
ATOM   13360 C CA  . SER E 1 295 ? 67.658  -3.663  87.839  1.00 35.21  ? 314 SER E CA  1 
ATOM   13361 C C   . SER E 1 295 ? 66.681  -4.365  88.761  1.00 32.76  ? 314 SER E C   1 
ATOM   13362 O O   . SER E 1 295 ? 67.036  -4.693  89.894  1.00 33.40  ? 314 SER E O   1 
ATOM   13363 C CB  . SER E 1 295 ? 68.082  -2.371  88.566  1.00 35.10  ? 314 SER E CB  1 
ATOM   13364 O OG  . SER E 1 295 ? 69.011  -1.615  87.827  1.00 36.91  ? 314 SER E OG  1 
ATOM   13365 N N   . LEU E 1 296 ? 65.433  -4.481  88.371  1.00 34.75  ? 315 LEU E N   1 
ATOM   13366 C CA  . LEU E 1 296 ? 64.494  -4.971  89.353  1.00 32.02  ? 315 LEU E CA  1 
ATOM   13367 C C   . LEU E 1 296 ? 64.639  -6.479  89.549  1.00 31.99  ? 315 LEU E C   1 
ATOM   13368 O O   . LEU E 1 296 ? 64.446  -6.966  90.665  1.00 31.33  ? 315 LEU E O   1 
ATOM   13369 C CB  . LEU E 1 296 ? 63.071  -4.614  88.938  1.00 29.97  ? 315 LEU E CB  1 
ATOM   13370 C CG  . LEU E 1 296 ? 62.014  -5.296  89.796  1.00 27.54  ? 315 LEU E CG  1 
ATOM   13371 C CD1 . LEU E 1 296 ? 62.015  -4.827  91.243  1.00 27.50  ? 315 LEU E CD1 1 
ATOM   13372 C CD2 . LEU E 1 296 ? 60.655  -5.117  89.165  1.00 27.58  ? 315 LEU E CD2 1 
ATOM   13373 N N   . LYS E 1 297 ? 64.987  -7.227  88.502  1.00 32.04  ? 316 LYS E N   1 
ATOM   13374 C CA  . LYS E 1 297 ? 64.816  -8.678  88.585  1.00 31.38  ? 316 LYS E CA  1 
ATOM   13375 C C   . LYS E 1 297 ? 65.735  -9.277  89.641  1.00 32.93  ? 316 LYS E C   1 
ATOM   13376 O O   . LYS E 1 297 ? 65.288  -10.108 90.434  1.00 32.39  ? 316 LYS E O   1 
ATOM   13377 C CB  . LYS E 1 297 ? 65.032  -9.338  87.229  1.00 33.24  ? 316 LYS E CB  1 
ATOM   13378 C CG  . LYS E 1 297 ? 64.743  -10.790 87.256  1.00 35.01  ? 316 LYS E CG  1 
ATOM   13379 C CD  . LYS E 1 297 ? 64.093  -11.358 85.949  1.00 37.28  ? 316 LYS E CD  1 
ATOM   13380 C CE  . LYS E 1 297 ? 64.745  -10.933 84.638  1.00 39.76  ? 316 LYS E CE  1 
ATOM   13381 N NZ  . LYS E 1 297 ? 66.198  -11.355 84.491  1.00 42.16  ? 316 LYS E NZ  1 
ATOM   13382 N N   . PHE E 1 298 ? 66.983  -8.804  89.730  1.00 31.22  ? 317 PHE E N   1 
ATOM   13383 C CA  . PHE E 1 298 ? 67.929  -9.443  90.650  1.00 32.78  ? 317 PHE E CA  1 
ATOM   13384 C C   . PHE E 1 298 ? 67.514  -9.280  92.106  1.00 32.09  ? 317 PHE E C   1 
ATOM   13385 O O   . PHE E 1 298 ? 67.374  -10.300 92.806  1.00 32.20  ? 317 PHE E O   1 
ATOM   13386 C CB  . PHE E 1 298 ? 69.356  -8.944  90.448  1.00 35.18  ? 317 PHE E CB  1 
ATOM   13387 C CG  . PHE E 1 298 ? 70.349  -9.644  91.357  1.00 36.99  ? 317 PHE E CG  1 
ATOM   13388 C CD1 . PHE E 1 298 ? 70.765  -10.955 91.089  1.00 37.57  ? 317 PHE E CD1 1 
ATOM   13389 C CD2 . PHE E 1 298 ? 70.843  -9.013  92.515  1.00 38.14  ? 317 PHE E CD2 1 
ATOM   13390 C CE1 . PHE E 1 298 ? 71.665  -11.592 91.947  1.00 39.47  ? 317 PHE E CE1 1 
ATOM   13391 C CE2 . PHE E 1 298 ? 71.721  -9.655  93.366  1.00 39.82  ? 317 PHE E CE2 1 
ATOM   13392 C CZ  . PHE E 1 298 ? 72.143  -10.941 93.085  1.00 40.39  ? 317 PHE E CZ  1 
ATOM   13393 N N   . PRO E 1 299 ? 67.305  -8.072  92.635  1.00 32.62  ? 318 PRO E N   1 
ATOM   13394 C CA  . PRO E 1 299 ? 66.915  -7.982  94.047  1.00 32.83  ? 318 PRO E CA  1 
ATOM   13395 C C   . PRO E 1 299 ? 65.566  -8.620  94.293  1.00 30.64  ? 318 PRO E C   1 
ATOM   13396 O O   . PRO E 1 299 ? 65.359  -9.223  95.347  1.00 31.00  ? 318 PRO E O   1 
ATOM   13397 C CB  . PRO E 1 299 ? 66.916  -6.468  94.337  1.00 33.60  ? 318 PRO E CB  1 
ATOM   13398 C CG  . PRO E 1 299 ? 66.739  -5.807  92.984  1.00 32.63  ? 318 PRO E CG  1 
ATOM   13399 C CD  . PRO E 1 299 ? 67.441  -6.738  92.011  1.00 33.08  ? 318 PRO E CD  1 
ATOM   13400 N N   . LEU E 1 300 ? 64.664  -8.554  93.327  1.00 33.43  ? 319 LEU E N   1 
ATOM   13401 C CA  . LEU E 1 300 ? 63.375  -9.212  93.473  1.00 31.66  ? 319 LEU E CA  1 
ATOM   13402 C C   . LEU E 1 300 ? 63.531  -10.725 93.559  1.00 32.33  ? 319 LEU E C   1 
ATOM   13403 O O   . LEU E 1 300 ? 62.853  -11.379 94.355  1.00 33.21  ? 319 LEU E O   1 
ATOM   13404 C CB  . LEU E 1 300 ? 62.477  -8.809  92.300  1.00 29.89  ? 319 LEU E CB  1 
ATOM   13405 C CG  . LEU E 1 300 ? 61.041  -9.374  92.321  1.00 29.69  ? 319 LEU E CG  1 
ATOM   13406 C CD1 . LEU E 1 300 ? 60.290  -9.005  93.596  1.00 29.47  ? 319 LEU E CD1 1 
ATOM   13407 C CD2 . LEU E 1 300 ? 60.277  -8.922  91.079  1.00 29.27  ? 319 LEU E CD2 1 
ATOM   13408 N N   . ALA E 1 301 ? 64.441  -11.297 92.779  1.00 31.63  ? 320 ALA E N   1 
ATOM   13409 C CA  . ALA E 1 301 ? 64.669  -12.747 92.861  1.00 33.52  ? 320 ALA E CA  1 
ATOM   13410 C C   . ALA E 1 301 ? 65.379  -13.103 94.160  1.00 34.78  ? 320 ALA E C   1 
ATOM   13411 O O   . ALA E 1 301 ? 65.113  -14.151 94.746  1.00 36.27  ? 320 ALA E O   1 
ATOM   13412 C CB  . ALA E 1 301 ? 65.471  -13.244 91.641  1.00 35.00  ? 320 ALA E CB  1 
ATOM   13413 N N   . CYS E 1 302 ? 66.268  -12.222 94.631  1.00 33.22  ? 321 CYS E N   1 
ATOM   13414 C CA  . CYS E 1 302 ? 66.895  -12.404 95.940  1.00 35.30  ? 321 CYS E CA  1 
ATOM   13415 C C   . CYS E 1 302 ? 65.855  -12.374 97.049  1.00 34.89  ? 321 CYS E C   1 
ATOM   13416 O O   . CYS E 1 302 ? 65.919  -13.163 97.984  1.00 36.38  ? 321 CYS E O   1 
ATOM   13417 C CB  . CYS E 1 302 ? 67.940  -11.322 96.165  1.00 37.08  ? 321 CYS E CB  1 
ATOM   13418 S SG  . CYS E 1 302 ? 69.427  -11.549 95.224  1.00 38.67  ? 321 CYS E SG  1 
ATOM   13419 N N   . PHE E 1 303 ? 64.887  -11.477 96.957  1.00 33.20  ? 322 PHE E N   1 
ATOM   13420 C CA  . PHE E 1 303 ? 63.880  -11.376 98.007  1.00 33.15  ? 322 PHE E CA  1 
ATOM   13421 C C   . PHE E 1 303 ? 62.974  -12.603 98.022  1.00 32.71  ? 322 PHE E C   1 
ATOM   13422 O O   . PHE E 1 303 ? 62.694  -13.170 99.088  1.00 34.26  ? 322 PHE E O   1 
ATOM   13423 C CB  . PHE E 1 303 ? 63.035  -10.101 97.807  1.00 31.56  ? 322 PHE E CB  1 
ATOM   13424 C CG  . PHE E 1 303 ? 61.839  -10.026 98.709  1.00 31.24  ? 322 PHE E CG  1 
ATOM   13425 C CD1 . PHE E 1 303 ? 61.998  -9.748  100.065 1.00 33.91  ? 322 PHE E CD1 1 
ATOM   13426 C CD2 . PHE E 1 303 ? 60.567  -10.272 98.207  1.00 29.64  ? 322 PHE E CD2 1 
ATOM   13427 C CE1 . PHE E 1 303 ? 60.907  -9.697  100.879 1.00 34.61  ? 322 PHE E CE1 1 
ATOM   13428 C CE2 . PHE E 1 303 ? 59.484  -10.242 99.025  1.00 30.04  ? 322 PHE E CE2 1 
ATOM   13429 C CZ  . PHE E 1 303 ? 59.634  -9.957  100.357 1.00 32.68  ? 322 PHE E CZ  1 
ATOM   13430 N N   . LEU E 1 304 ? 62.470  -13.000 96.842  1.00 34.05  ? 323 LEU E N   1 
ATOM   13431 C CA  . LEU E 1 304 ? 61.549  -14.136 96.739  1.00 34.75  ? 323 LEU E CA  1 
ATOM   13432 C C   . LEU E 1 304 ? 62.231  -15.474 97.023  1.00 37.26  ? 323 LEU E C   1 
ATOM   13433 O O   . LEU E 1 304 ? 61.582  -16.417 97.460  1.00 38.70  ? 323 LEU E O   1 
ATOM   13434 C CB  . LEU E 1 304 ? 60.931  -14.163 95.343  1.00 33.92  ? 323 LEU E CB  1 
ATOM   13435 C CG  . LEU E 1 304 ? 59.934  -13.073 94.962  1.00 32.21  ? 323 LEU E CG  1 
ATOM   13436 C CD1 . LEU E 1 304 ? 59.487  -13.243 93.501  1.00 31.92  ? 323 LEU E CD1 1 
ATOM   13437 C CD2 . LEU E 1 304 ? 58.761  -13.141 95.950  1.00 32.73  ? 323 LEU E CD2 1 
ATOM   13438 N N   . ALA E 1 305 ? 63.529  -15.580 96.757  1.00 34.98  ? 324 ALA E N   1 
ATOM   13439 C CA  . ALA E 1 305 ? 64.266  -16.777 97.132  1.00 37.82  ? 324 ALA E CA  1 
ATOM   13440 C C   . ALA E 1 305 ? 64.211  -17.009 98.638  1.00 38.93  ? 324 ALA E C   1 
ATOM   13441 O O   . ALA E 1 305 ? 64.056  -18.154 99.086  1.00 41.40  ? 324 ALA E O   1 
ATOM   13442 C CB  . ALA E 1 305 ? 65.721  -16.652 96.663  1.00 38.53  ? 324 ALA E CB  1 
ATOM   13443 N N   . GLY E 1 306 ? 64.367  -15.946 99.439  1.00 37.23  ? 325 GLY E N   1 
ATOM   13444 C CA  . GLY E 1 306 ? 64.437  -16.064 100.878 1.00 38.55  ? 325 GLY E CA  1 
ATOM   13445 C C   . GLY E 1 306 ? 63.188  -15.709 101.631 1.00 37.61  ? 325 GLY E C   1 
ATOM   13446 O O   . GLY E 1 306 ? 63.135  -15.898 102.852 1.00 39.70  ? 325 GLY E O   1 
ATOM   13447 N N   . ALA E 1 307 ? 62.169  -15.218 100.960 1.00 38.39  ? 326 ALA E N   1 
ATOM   13448 C CA  . ALA E 1 307 ? 61.090  -14.564 101.665 1.00 38.58  ? 326 ALA E CA  1 
ATOM   13449 C C   . ALA E 1 307 ? 60.218  -15.583 102.372 1.00 40.16  ? 326 ALA E C   1 
ATOM   13450 O O   . ALA E 1 307 ? 59.993  -16.696 101.889 1.00 40.17  ? 326 ALA E O   1 
ATOM   13451 C CB  . ALA E 1 307 ? 60.259  -13.734 100.696 1.00 36.01  ? 326 ALA E CB  1 
ATOM   13452 N N   . GLN E 1 308 ? 59.698  -15.191 103.516 1.00 38.90  ? 327 GLN E N   1 
ATOM   13453 C CA  . GLN E 1 308 ? 58.806  -16.027 104.305 1.00 40.58  ? 327 GLN E CA  1 
ATOM   13454 C C   . GLN E 1 308 ? 57.605  -15.172 104.665 1.00 40.43  ? 327 GLN E C   1 
ATOM   13455 O O   . GLN E 1 308 ? 57.515  -14.006 104.305 1.00 38.78  ? 327 GLN E O   1 
ATOM   13456 C CB  . GLN E 1 308 ? 59.537  -16.573 105.537 1.00 43.72  ? 327 GLN E CB  1 
ATOM   13457 C CG  . GLN E 1 308 ? 60.935  -17.029 105.204 1.00 44.33  ? 327 GLN E CG  1 
ATOM   13458 C CD  . GLN E 1 308 ? 60.943  -18.388 104.487 1.00 45.04  ? 327 GLN E CD  1 
ATOM   13459 O OE1 . GLN E 1 308 ? 60.171  -19.313 104.824 1.00 47.07  ? 327 GLN E OE1 1 
ATOM   13460 N NE2 . GLN E 1 308 ? 61.854  -18.530 103.514 1.00 44.72  ? 327 GLN E NE2 1 
ATOM   13461 N N   . GLU E 1 309 ? 56.665  -15.741 105.409 1.00 40.25  ? 328 GLU E N   1 
ATOM   13462 C CA  . GLU E 1 309 ? 55.556  -14.934 105.903 1.00 40.08  ? 328 GLU E CA  1 
ATOM   13463 C C   . GLU E 1 309 ? 56.122  -13.723 106.636 1.00 39.90  ? 328 GLU E C   1 
ATOM   13464 O O   . GLU E 1 309 ? 57.176  -13.796 107.273 1.00 41.52  ? 328 GLU E O   1 
ATOM   13465 C CB  . GLU E 1 309 ? 54.626  -15.754 106.801 1.00 42.71  ? 328 GLU E CB  1 
ATOM   13466 N N   . ASN E 1 310 ? 55.472  -12.573 106.444 1.00 40.79  ? 329 ASN E N   1 
ATOM   13467 C CA  . ASN E 1 310 ? 55.840  -11.313 107.089 1.00 40.98  ? 329 ASN E CA  1 
ATOM   13468 C C   . ASN E 1 310 ? 57.109  -10.669 106.526 1.00 40.51  ? 329 ASN E C   1 
ATOM   13469 O O   . ASN E 1 310 ? 57.716  -9.815  107.190 1.00 41.64  ? 329 ASN E O   1 
ATOM   13470 C CB  . ASN E 1 310 ? 55.997  -11.504 108.602 1.00 43.22  ? 329 ASN E CB  1 
ATOM   13471 C CG  . ASN E 1 310 ? 54.837  -12.237 109.216 1.00 43.93  ? 329 ASN E CG  1 
ATOM   13472 O OD1 . ASN E 1 310 ? 55.019  -13.176 110.034 1.00 46.54  ? 329 ASN E OD1 1 
ATOM   13473 N ND2 . ASN E 1 310 ? 53.635  -11.851 108.829 1.00 42.35  ? 329 ASN E ND2 1 
ATOM   13474 N N   . CYS E 1 311 ? 57.523  -11.038 105.327 1.00 39.40  ? 330 CYS E N   1 
ATOM   13475 C CA  . CYS E 1 311 ? 58.624  -10.370 104.647 1.00 38.66  ? 330 CYS E CA  1 
ATOM   13476 C C   . CYS E 1 311 ? 58.091  -9.472  103.532 1.00 36.16  ? 330 CYS E C   1 
ATOM   13477 O O   . CYS E 1 311 ? 57.212  -9.871  102.751 1.00 34.55  ? 330 CYS E O   1 
ATOM   13478 C CB  . CYS E 1 311 ? 59.613  -11.372 104.058 1.00 38.95  ? 330 CYS E CB  1 
ATOM   13479 S SG  . CYS E 1 311 ? 60.442  -12.372 105.242 1.00 42.23  ? 330 CYS E SG  1 
ATOM   13480 N N   . TYR E 1 312 ? 58.630  -8.253  103.462 1.00 37.51  ? 331 TYR E N   1 
ATOM   13481 C CA  . TYR E 1 312 ? 58.162  -7.216  102.549 1.00 34.90  ? 331 TYR E CA  1 
ATOM   13482 C C   . TYR E 1 312 ? 59.327  -6.716  101.704 1.00 34.05  ? 331 TYR E C   1 
ATOM   13483 O O   . TYR E 1 312 ? 60.476  -6.683  102.166 1.00 36.26  ? 331 TYR E O   1 
ATOM   13484 C CB  . TYR E 1 312 ? 57.494  -6.084  103.330 1.00 35.57  ? 331 TYR E CB  1 
ATOM   13485 C CG  . TYR E 1 312 ? 56.249  -6.538  104.077 1.00 36.38  ? 331 TYR E CG  1 
ATOM   13486 C CD1 . TYR E 1 312 ? 56.357  -7.135  105.332 1.00 39.06  ? 331 TYR E CD1 1 
ATOM   13487 C CD2 . TYR E 1 312 ? 54.963  -6.381  103.520 1.00 34.69  ? 331 TYR E CD2 1 
ATOM   13488 C CE1 . TYR E 1 312 ? 55.242  -7.555  106.018 1.00 39.62  ? 331 TYR E CE1 1 
ATOM   13489 C CE2 . TYR E 1 312 ? 53.816  -6.839  104.209 1.00 35.78  ? 331 TYR E CE2 1 
ATOM   13490 C CZ  . TYR E 1 312 ? 53.975  -7.423  105.453 1.00 38.56  ? 331 TYR E CZ  1 
ATOM   13491 O OH  . TYR E 1 312 ? 52.899  -7.858  106.185 1.00 40.02  ? 331 TYR E OH  1 
ATOM   13492 N N   . PHE E 1 313 ? 59.042  -6.415  100.451 1.00 33.58  ? 332 PHE E N   1 
ATOM   13493 C CA  . PHE E 1 313 ? 59.995  -5.833  99.522  1.00 32.35  ? 332 PHE E CA  1 
ATOM   13494 C C   . PHE E 1 313 ? 59.681  -4.347  99.294  1.00 30.92  ? 332 PHE E C   1 
ATOM   13495 O O   . PHE E 1 313 ? 58.530  -3.904  99.363  1.00 29.57  ? 332 PHE E O   1 
ATOM   13496 C CB  . PHE E 1 313 ? 59.928  -6.602  98.207  1.00 30.32  ? 332 PHE E CB  1 
ATOM   13497 C CG  . PHE E 1 313 ? 61.037  -6.314  97.250  1.00 29.72  ? 332 PHE E CG  1 
ATOM   13498 C CD1 . PHE E 1 313 ? 62.352  -6.457  97.617  1.00 32.16  ? 332 PHE E CD1 1 
ATOM   13499 C CD2 . PHE E 1 313 ? 60.747  -5.956  95.950  1.00 27.57  ? 332 PHE E CD2 1 
ATOM   13500 C CE1 . PHE E 1 313 ? 63.360  -6.197  96.698  1.00 32.64  ? 332 PHE E CE1 1 
ATOM   13501 C CE2 . PHE E 1 313 ? 61.747  -5.713  95.032  1.00 28.09  ? 332 PHE E CE2 1 
ATOM   13502 C CZ  . PHE E 1 313 ? 63.053  -5.842  95.397  1.00 30.71  ? 332 PHE E CZ  1 
ATOM   13503 N N   . ILE E 1 314 ? 60.746  -3.576  99.065  1.00 32.21  ? 333 ILE E N   1 
ATOM   13504 C CA  . ILE E 1 314 ? 60.699  -2.140  98.775  1.00 30.62  ? 333 ILE E CA  1 
ATOM   13505 C C   . ILE E 1 314 ? 61.783  -1.912  97.736  1.00 30.15  ? 333 ILE E C   1 
ATOM   13506 O O   . ILE E 1 314 ? 62.939  -2.278  97.961  1.00 32.83  ? 333 ILE E O   1 
ATOM   13507 C CB  . ILE E 1 314 ? 60.987  -1.241  99.986  1.00 32.41  ? 333 ILE E CB  1 
ATOM   13508 C CG1 . ILE E 1 314 ? 60.011  -1.519  101.115 1.00 34.19  ? 333 ILE E CG1 1 
ATOM   13509 C CG2 . ILE E 1 314 ? 60.931  0.314   99.608  1.00 30.94  ? 333 ILE E CG2 1 
ATOM   13510 C CD1 . ILE E 1 314 ? 60.161  -0.520  102.277 1.00 36.04  ? 333 ILE E CD1 1 
ATOM   13511 N N   . TYR E 1 315 ? 61.427  -1.317  96.608  1.00 29.07  ? 334 TYR E N   1 
ATOM   13512 C CA  . TYR E 1 315 ? 62.356  -1.121  95.506  1.00 29.37  ? 334 TYR E CA  1 
ATOM   13513 C C   . TYR E 1 315 ? 62.226  0.302   94.996  1.00 28.50  ? 334 TYR E C   1 
ATOM   13514 O O   . TYR E 1 315 ? 61.130  0.744   94.659  1.00 27.23  ? 334 TYR E O   1 
ATOM   13515 C CB  . TYR E 1 315 ? 62.065  -2.111  94.380  1.00 28.59  ? 334 TYR E CB  1 
ATOM   13516 C CG  . TYR E 1 315 ? 62.986  -1.999  93.213  1.00 29.72  ? 334 TYR E CG  1 
ATOM   13517 C CD1 . TYR E 1 315 ? 64.285  -2.415  93.303  1.00 32.05  ? 334 TYR E CD1 1 
ATOM   13518 C CD2 . TYR E 1 315 ? 62.550  -1.477  92.013  1.00 29.07  ? 334 TYR E CD2 1 
ATOM   13519 C CE1 . TYR E 1 315 ? 65.136  -2.304  92.247  1.00 33.74  ? 334 TYR E CE1 1 
ATOM   13520 C CE2 . TYR E 1 315 ? 63.385  -1.395  90.946  1.00 30.93  ? 334 TYR E CE2 1 
ATOM   13521 C CZ  . TYR E 1 315 ? 64.684  -1.800  91.072  1.00 33.34  ? 334 TYR E CZ  1 
ATOM   13522 O OH  . TYR E 1 315 ? 65.543  -1.698  90.005  1.00 35.94  ? 334 TYR E OH  1 
ATOM   13523 N N   . ASN E 1 316 ? 63.336  1.014   94.937  1.00 33.44  ? 335 ASN E N   1 
ATOM   13524 C CA  . ASN E 1 316 ? 63.339  2.415   94.542  1.00 33.13  ? 335 ASN E CA  1 
ATOM   13525 C C   . ASN E 1 316 ? 64.767  2.894   94.682  1.00 35.46  ? 335 ASN E C   1 
ATOM   13526 O O   . ASN E 1 316 ? 65.675  2.075   94.878  1.00 37.00  ? 335 ASN E O   1 
ATOM   13527 C CB  . ASN E 1 316 ? 62.396  3.245   95.373  1.00 32.01  ? 335 ASN E CB  1 
ATOM   13528 C CG  . ASN E 1 316 ? 62.654  3.116   96.841  1.00 33.08  ? 335 ASN E CG  1 
ATOM   13529 O OD1 . ASN E 1 316 ? 63.803  3.199   97.332  1.00 34.98  ? 335 ASN E OD1 1 
ATOM   13530 N ND2 . ASN E 1 316 ? 61.560  2.967   97.587  1.00 32.31  ? 335 ASN E ND2 1 
ATOM   13531 N N   . TRP E 1 317 ? 64.977  4.217   94.617  1.00 34.66  ? 336 TRP E N   1 
ATOM   13532 C CA  . TRP E 1 317 ? 66.327  4.745   94.700  1.00 35.17  ? 336 TRP E CA  1 
ATOM   13533 C C   . TRP E 1 317 ? 66.437  5.865   95.732  1.00 36.76  ? 336 TRP E C   1 
ATOM   13534 O O   . TRP E 1 317 ? 67.443  6.597   95.740  1.00 37.90  ? 336 TRP E O   1 
ATOM   13535 C CB  . TRP E 1 317 ? 66.802  5.192   93.319  1.00 35.88  ? 336 TRP E CB  1 
ATOM   13536 C CG  . TRP E 1 317 ? 65.969  6.201   92.596  1.00 37.40  ? 336 TRP E CG  1 
ATOM   13537 C CD1 . TRP E 1 317 ? 66.028  7.538   92.741  1.00 39.38  ? 336 TRP E CD1 1 
ATOM   13538 C CD2 . TRP E 1 317 ? 64.987  5.950   91.560  1.00 37.61  ? 336 TRP E CD2 1 
ATOM   13539 N NE1 . TRP E 1 317 ? 65.153  8.138   91.882  1.00 40.61  ? 336 TRP E NE1 1 
ATOM   13540 C CE2 . TRP E 1 317 ? 64.484  7.190   91.164  1.00 39.40  ? 336 TRP E CE2 1 
ATOM   13541 C CE3 . TRP E 1 317 ? 64.490  4.794   90.937  1.00 36.82  ? 336 TRP E CE3 1 
ATOM   13542 C CZ2 . TRP E 1 317 ? 63.523  7.324   90.171  1.00 40.47  ? 336 TRP E CZ2 1 
ATOM   13543 C CZ3 . TRP E 1 317 ? 63.516  4.922   89.964  1.00 37.86  ? 336 TRP E CZ3 1 
ATOM   13544 C CH2 . TRP E 1 317 ? 63.049  6.170   89.585  1.00 39.57  ? 336 TRP E CH2 1 
ATOM   13545 N N   . GLY E 1 318 ? 65.464  5.994   96.630  1.00 37.38  ? 337 GLY E N   1 
ATOM   13546 C CA  . GLY E 1 318 ? 65.663  6.867   97.772  1.00 39.08  ? 337 GLY E CA  1 
ATOM   13547 C C   . GLY E 1 318 ? 64.441  6.923   98.655  1.00 39.82  ? 337 GLY E C   1 
ATOM   13548 O O   . GLY E 1 318 ? 63.468  6.202   98.440  1.00 38.70  ? 337 GLY E O   1 
ATOM   13549 N N   . TYR E 1 319 ? 64.480  7.849   99.623  1.00 44.02  ? 338 TYR E N   1 
ATOM   13550 C CA  . TYR E 1 319 ? 63.440  7.996   100.637 1.00 44.47  ? 338 TYR E CA  1 
ATOM   13551 C C   . TYR E 1 319 ? 62.520  9.188   100.436 1.00 45.92  ? 338 TYR E C   1 
ATOM   13552 O O   . TYR E 1 319 ? 61.556  9.349   101.206 1.00 46.52  ? 338 TYR E O   1 
ATOM   13553 C CB  . TYR E 1 319 ? 64.088  8.079   102.018 1.00 45.50  ? 338 TYR E CB  1 
ATOM   13554 C CG  . TYR E 1 319 ? 64.748  6.773   102.334 1.00 44.29  ? 338 TYR E CG  1 
ATOM   13555 C CD1 . TYR E 1 319 ? 63.976  5.620   102.562 1.00 42.87  ? 338 TYR E CD1 1 
ATOM   13556 C CD2 . TYR E 1 319 ? 66.128  6.656   102.343 1.00 45.03  ? 338 TYR E CD2 1 
ATOM   13557 C CE1 . TYR E 1 319 ? 64.564  4.408   102.819 1.00 41.61  ? 338 TYR E CE1 1 
ATOM   13558 C CE2 . TYR E 1 319 ? 66.727  5.436   102.598 1.00 43.52  ? 338 TYR E CE2 1 
ATOM   13559 C CZ  . TYR E 1 319 ? 65.937  4.315   102.831 1.00 41.82  ? 338 TYR E CZ  1 
ATOM   13560 O OH  . TYR E 1 319 ? 66.516  3.093   103.104 1.00 40.79  ? 338 TYR E OH  1 
ATOM   13561 N N   . ARG E 1 320 ? 62.766  10.018  99.424  1.00 46.91  ? 339 ARG E N   1 
ATOM   13562 C CA  . ARG E 1 320 ? 61.810  11.036  99.003  1.00 48.13  ? 339 ARG E CA  1 
ATOM   13563 C C   . ARG E 1 320 ? 60.869  10.361  98.009  1.00 46.78  ? 339 ARG E C   1 
ATOM   13564 O O   . ARG E 1 320 ? 61.294  9.525   97.198  1.00 45.85  ? 339 ARG E O   1 
ATOM   13565 C CB  . ARG E 1 320 ? 62.485  12.251  98.365  1.00 50.04  ? 339 ARG E CB  1 
ATOM   13566 C CG  . ARG E 1 320 ? 63.447  13.103  99.258  1.00 52.36  ? 339 ARG E CG  1 
ATOM   13567 C CD  . ARG E 1 320 ? 62.822  13.682  100.545 1.00 55.70  ? 339 ARG E CD  1 
ATOM   13568 N NE  . ARG E 1 320 ? 63.530  13.137  101.706 1.00 58.06  ? 339 ARG E NE  1 
ATOM   13569 C CZ  . ARG E 1 320 ? 62.967  12.720  102.841 1.00 59.76  ? 339 ARG E CZ  1 
ATOM   13570 N NH1 . ARG E 1 320 ? 61.690  12.973  103.122 1.00 60.16  ? 339 ARG E NH1 1 
ATOM   13571 N NH2 . ARG E 1 320 ? 63.701  12.019  103.713 1.00 60.64  ? 339 ARG E NH2 1 
ATOM   13572 N N   . MET E 1 321 ? 59.586  10.689  98.097  1.00 47.68  ? 340 MET E N   1 
ATOM   13573 C CA  . MET E 1 321 ? 58.606  10.075  97.206  1.00 46.95  ? 340 MET E CA  1 
ATOM   13574 C C   . MET E 1 321 ? 59.039  10.096  95.748  1.00 46.62  ? 340 MET E C   1 
ATOM   13575 O O   . MET E 1 321 ? 58.788  9.147   95.008  1.00 45.63  ? 340 MET E O   1 
ATOM   13576 C CB  . MET E 1 321 ? 57.272  10.817  97.326  1.00 47.90  ? 340 MET E CB  1 
ATOM   13577 C CG  . MET E 1 321 ? 56.070  9.983   96.916  1.00 47.27  ? 340 MET E CG  1 
ATOM   13578 S SD  . MET E 1 321 ? 54.559  10.978  96.907  1.00 48.79  ? 340 MET E SD  1 
ATOM   13579 C CE  . MET E 1 321 ? 54.925  12.285  95.736  1.00 50.12  ? 340 MET E CE  1 
ATOM   13580 N N   . GLU E 1 322 ? 59.611  11.210  95.290  1.00 44.63  ? 341 GLU E N   1 
ATOM   13581 C CA  . GLU E 1 322 ? 59.932  11.330  93.878  1.00 45.09  ? 341 GLU E CA  1 
ATOM   13582 C C   . GLU E 1 322 ? 61.083  10.426  93.478  1.00 44.09  ? 341 GLU E C   1 
ATOM   13583 O O   . GLU E 1 322 ? 61.370  10.325  92.279  1.00 44.35  ? 341 GLU E O   1 
ATOM   13584 C CB  . GLU E 1 322 ? 60.230  12.801  93.518  1.00 47.72  ? 341 GLU E CB  1 
ATOM   13585 C CG  . GLU E 1 322 ? 61.538  13.418  94.033  1.00 49.83  ? 341 GLU E CG  1 
ATOM   13586 C CD  . GLU E 1 322 ? 61.394  14.121  95.413  1.00 51.40  ? 341 GLU E CD  1 
ATOM   13587 O OE1 . GLU E 1 322 ? 62.350  14.874  95.793  1.00 51.14  ? 341 GLU E OE1 1 
ATOM   13588 O OE2 . GLU E 1 322 ? 60.339  13.911  96.100  1.00 52.91  ? 341 GLU E OE2 1 
ATOM   13589 N N   . ASN E 1 323 ? 61.710  9.750   94.447  1.00 43.29  ? 342 ASN E N   1 
ATOM   13590 C CA  . ASN E 1 323 ? 62.797  8.828   94.176  1.00 42.26  ? 342 ASN E CA  1 
ATOM   13591 C C   . ASN E 1 323 ? 62.356  7.432   93.732  1.00 40.34  ? 342 ASN E C   1 
ATOM   13592 O O   . ASN E 1 323 ? 62.884  6.417   94.205  1.00 38.93  ? 342 ASN E O   1 
ATOM   13593 C CB  . ASN E 1 323 ? 63.672  8.652   95.437  1.00 42.42  ? 342 ASN E CB  1 
ATOM   13594 C CG  . ASN E 1 323 ? 64.297  9.954   95.902  1.00 44.04  ? 342 ASN E CG  1 
ATOM   13595 O OD1 . ASN E 1 323 ? 64.524  10.149  97.092  1.00 44.95  ? 342 ASN E OD1 1 
ATOM   13596 N ND2 . ASN E 1 323 ? 64.580  10.848  94.949  1.00 45.42  ? 342 ASN E ND2 1 
ATOM   13597 N N   . GLY E 1 324 ? 61.431  7.367   92.785  1.00 40.06  ? 343 GLY E N   1 
ATOM   13598 C CA  . GLY E 1 324 ? 60.971  6.053   92.355  1.00 38.97  ? 343 GLY E CA  1 
ATOM   13599 C C   . GLY E 1 324 ? 60.029  5.365   93.314  1.00 38.45  ? 343 GLY E C   1 
ATOM   13600 O O   . GLY E 1 324 ? 59.659  4.226   93.077  1.00 37.54  ? 343 GLY E O   1 
ATOM   13601 N N   . CYS E 1 325 ? 59.596  6.037   94.374  1.00 39.23  ? 344 CYS E N   1 
ATOM   13602 C CA  . CYS E 1 325 ? 58.861  5.323   95.394  1.00 38.34  ? 344 CYS E CA  1 
ATOM   13603 C C   . CYS E 1 325 ? 57.487  4.923   94.941  1.00 38.37  ? 344 CYS E C   1 
ATOM   13604 O O   . CYS E 1 325 ? 56.931  3.984   95.524  1.00 37.92  ? 344 CYS E O   1 
ATOM   13605 C CB  . CYS E 1 325 ? 58.737  6.147   96.663  1.00 39.46  ? 344 CYS E CB  1 
ATOM   13606 S SG  . CYS E 1 325 ? 60.327  6.252   97.446  1.00 40.04  ? 344 CYS E SG  1 
ATOM   13607 N N   . LEU E 1 326 ? 56.927  5.590   93.933  1.00 37.88  ? 345 LEU E N   1 
ATOM   13608 C CA  . LEU E 1 326 ? 55.624  5.211   93.415  1.00 38.33  ? 345 LEU E CA  1 
ATOM   13609 C C   . LEU E 1 326 ? 55.693  4.697   91.980  1.00 38.94  ? 345 LEU E C   1 
ATOM   13610 O O   . LEU E 1 326 ? 54.662  4.606   91.306  1.00 40.13  ? 345 LEU E O   1 
ATOM   13611 C CB  . LEU E 1 326 ? 54.649  6.378   93.519  1.00 39.96  ? 345 LEU E CB  1 
ATOM   13612 C CG  . LEU E 1 326 ? 54.478  6.922   94.930  1.00 40.38  ? 345 LEU E CG  1 
ATOM   13613 C CD1 . LEU E 1 326 ? 53.333  7.870   95.019  1.00 42.05  ? 345 LEU E CD1 1 
ATOM   13614 C CD2 . LEU E 1 326 ? 54.255  5.822   95.918  1.00 39.21  ? 345 LEU E CD2 1 
ATOM   13615 N N   . GLU E 1 327 ? 56.877  4.342   91.502  1.00 37.71  ? 346 GLU E N   1 
ATOM   13616 C CA  . GLU E 1 327 ? 56.957  3.574   90.276  1.00 38.02  ? 346 GLU E CA  1 
ATOM   13617 C C   . GLU E 1 327 ? 56.345  2.189   90.511  1.00 37.76  ? 346 GLU E C   1 
ATOM   13618 O O   . GLU E 1 327 ? 56.289  1.680   91.630  1.00 37.69  ? 346 GLU E O   1 
ATOM   13619 C CB  . GLU E 1 327 ? 58.405  3.465   89.813  1.00 37.50  ? 346 GLU E CB  1 
ATOM   13620 C CG  . GLU E 1 327 ? 59.075  4.836   89.577  1.00 38.53  ? 346 GLU E CG  1 
ATOM   13621 C CD  . GLU E 1 327 ? 58.683  5.479   88.232  1.00 40.73  ? 346 GLU E CD  1 
ATOM   13622 O OE1 . GLU E 1 327 ? 58.708  4.836   87.168  1.00 41.77  ? 346 GLU E OE1 1 
ATOM   13623 O OE2 . GLU E 1 327 ? 58.359  6.685   88.234  1.00 42.00  ? 346 GLU E OE2 1 
ATOM   13624 N N   . TRP E 1 328 ? 55.830  1.595   89.464  1.00 39.86  ? 347 TRP E N   1 
ATOM   13625 C CA  . TRP E 1 328 ? 55.226  0.282   89.567  1.00 39.61  ? 347 TRP E CA  1 
ATOM   13626 C C   . TRP E 1 328 ? 55.746  -0.540  88.411  1.00 40.40  ? 347 TRP E C   1 
ATOM   13627 O O   . TRP E 1 328 ? 56.280  -0.028  87.428  1.00 41.57  ? 347 TRP E O   1 
ATOM   13628 C CB  . TRP E 1 328 ? 53.707  0.331   89.547  1.00 40.93  ? 347 TRP E CB  1 
ATOM   13629 C CG  . TRP E 1 328 ? 52.997  -0.815  90.264  1.00 40.29  ? 347 TRP E CG  1 
ATOM   13630 C CD1 . TRP E 1 328 ? 52.077  -1.685  89.706  1.00 41.38  ? 347 TRP E CD1 1 
ATOM   13631 C CD2 . TRP E 1 328 ? 53.101  -1.195  91.662  1.00 38.47  ? 347 TRP E CD2 1 
ATOM   13632 N NE1 . TRP E 1 328 ? 51.623  -2.589  90.656  1.00 40.71  ? 347 TRP E NE1 1 
ATOM   13633 C CE2 . TRP E 1 328 ? 52.240  -2.316  91.859  1.00 38.73  ? 347 TRP E CE2 1 
ATOM   13634 C CE3 . TRP E 1 328 ? 53.859  -0.734  92.746  1.00 37.14  ? 347 TRP E CE3 1 
ATOM   13635 C CZ2 . TRP E 1 328 ? 52.112  -2.954  93.104  1.00 37.48  ? 347 TRP E CZ2 1 
ATOM   13636 C CZ3 . TRP E 1 328 ? 53.712  -1.377  93.990  1.00 36.08  ? 347 TRP E CZ3 1 
ATOM   13637 C CH2 . TRP E 1 328 ? 52.830  -2.456  94.152  1.00 36.34  ? 347 TRP E CH2 1 
ATOM   13638 N N   . TYR E 1 329 ? 55.647  -1.840  88.585  1.00 38.41  ? 348 TYR E N   1 
ATOM   13639 C CA  . TYR E 1 329 ? 56.339  -2.815  87.747  1.00 38.81  ? 348 TYR E CA  1 
ATOM   13640 C C   . TYR E 1 329 ? 55.331  -3.939  87.601  1.00 39.64  ? 348 TYR E C   1 
ATOM   13641 O O   . TYR E 1 329 ? 54.629  -4.272  88.574  1.00 38.96  ? 348 TYR E O   1 
ATOM   13642 C CB  . TYR E 1 329 ? 57.638  -3.271  88.400  1.00 36.84  ? 348 TYR E CB  1 
ATOM   13643 C CG  . TYR E 1 329 ? 58.543  -2.100  88.762  1.00 35.99  ? 348 TYR E CG  1 
ATOM   13644 C CD1 . TYR E 1 329 ? 58.421  -1.442  89.996  1.00 34.86  ? 348 TYR E CD1 1 
ATOM   13645 C CD2 . TYR E 1 329 ? 59.499  -1.626  87.860  1.00 36.65  ? 348 TYR E CD2 1 
ATOM   13646 C CE1 . TYR E 1 329 ? 59.228  -0.373  90.313  1.00 34.58  ? 348 TYR E CE1 1 
ATOM   13647 C CE2 . TYR E 1 329 ? 60.308  -0.546  88.173  1.00 36.00  ? 348 TYR E CE2 1 
ATOM   13648 C CZ  . TYR E 1 329 ? 60.166  0.073   89.393  1.00 35.08  ? 348 TYR E CZ  1 
ATOM   13649 O OH  . TYR E 1 329 ? 61.003  1.131   89.659  1.00 35.19  ? 348 TYR E OH  1 
ATOM   13650 N N   . PRO E 1 330 ? 55.187  -4.496  86.397  1.00 39.40  ? 349 PRO E N   1 
ATOM   13651 C CA  . PRO E 1 330 ? 54.226  -5.605  86.236  1.00 40.46  ? 349 PRO E CA  1 
ATOM   13652 C C   . PRO E 1 330 ? 54.477  -6.772  87.181  1.00 38.42  ? 349 PRO E C   1 
ATOM   13653 O O   . PRO E 1 330 ? 53.519  -7.453  87.581  1.00 38.78  ? 349 PRO E O   1 
ATOM   13654 C CB  . PRO E 1 330 ? 54.394  -6.015  84.764  1.00 43.23  ? 349 PRO E CB  1 
ATOM   13655 C CG  . PRO E 1 330 ? 55.667  -5.395  84.309  1.00 43.41  ? 349 PRO E CG  1 
ATOM   13656 C CD  . PRO E 1 330 ? 55.896  -4.173  85.145  1.00 41.25  ? 349 PRO E CD  1 
ATOM   13657 N N   . GLU E 1 331 ? 55.733  -6.995  87.600  1.00 41.19  ? 350 GLU E N   1 
ATOM   13658 C CA  . GLU E 1 331 ? 55.986  -8.108  88.523  1.00 39.41  ? 350 GLU E CA  1 
ATOM   13659 C C   . GLU E 1 331 ? 55.183  -7.973  89.814  1.00 38.38  ? 350 GLU E C   1 
ATOM   13660 O O   . GLU E 1 331 ? 54.884  -8.973  90.476  1.00 38.54  ? 350 GLU E O   1 
ATOM   13661 C CB  . GLU E 1 331 ? 57.457  -8.222  88.872  1.00 38.43  ? 350 GLU E CB  1 
ATOM   13662 C CG  . GLU E 1 331 ? 58.338  -8.748  87.782  1.00 39.74  ? 350 GLU E CG  1 
ATOM   13663 C CD  . GLU E 1 331 ? 58.685  -7.682  86.769  1.00 41.71  ? 350 GLU E CD  1 
ATOM   13664 O OE1 . GLU E 1 331 ? 58.063  -6.588  86.818  1.00 41.48  ? 350 GLU E OE1 1 
ATOM   13665 O OE2 . GLU E 1 331 ? 59.588  -7.934  85.933  1.00 43.52  ? 350 GLU E OE2 1 
ATOM   13666 N N   . PHE E 1 332 ? 54.828  -6.765  90.192  1.00 37.74  ? 351 PHE E N   1 
ATOM   13667 C CA  . PHE E 1 332 ? 54.103  -6.588  91.430  1.00 36.92  ? 351 PHE E CA  1 
ATOM   13668 C C   . PHE E 1 332 ? 52.637  -6.889  91.269  1.00 38.16  ? 351 PHE E C   1 
ATOM   13669 O O   . PHE E 1 332 ? 51.933  -6.979  92.262  1.00 37.94  ? 351 PHE E O   1 
ATOM   13670 C CB  . PHE E 1 332 ? 54.365  -5.167  91.939  1.00 36.37  ? 351 PHE E CB  1 
ATOM   13671 C CG  . PHE E 1 332 ? 55.840  -4.896  92.274  1.00 34.81  ? 351 PHE E CG  1 
ATOM   13672 C CD1 . PHE E 1 332 ? 56.768  -5.942  92.362  1.00 33.74  ? 351 PHE E CD1 1 
ATOM   13673 C CD2 . PHE E 1 332 ? 56.285  -3.607  92.486  1.00 34.90  ? 351 PHE E CD2 1 
ATOM   13674 C CE1 . PHE E 1 332 ? 58.098  -5.698  92.662  1.00 32.83  ? 351 PHE E CE1 1 
ATOM   13675 C CE2 . PHE E 1 332 ? 57.633  -3.347  92.797  1.00 33.60  ? 351 PHE E CE2 1 
ATOM   13676 C CZ  . PHE E 1 332 ? 58.544  -4.403  92.891  1.00 32.52  ? 351 PHE E CZ  1 
ATOM   13677 N N   . ASP E 1 333 ? 52.165  -7.095  90.047  1.00 38.23  ? 352 ASP E N   1 
ATOM   13678 C CA  . ASP E 1 333 ? 50.776  -7.475  89.779  1.00 39.96  ? 352 ASP E CA  1 
ATOM   13679 C C   . ASP E 1 333 ? 50.600  -8.978  89.547  1.00 40.60  ? 352 ASP E C   1 
ATOM   13680 O O   . ASP E 1 333 ? 49.493  -9.506  89.629  1.00 42.36  ? 352 ASP E O   1 
ATOM   13681 C CB  . ASP E 1 333 ? 50.257  -6.733  88.534  1.00 42.30  ? 352 ASP E CB  1 
ATOM   13682 C CG  . ASP E 1 333 ? 50.170  -5.203  88.710  1.00 42.79  ? 352 ASP E CG  1 
ATOM   13683 O OD1 . ASP E 1 333 ? 50.051  -4.751  89.875  1.00 41.63  ? 352 ASP E OD1 1 
ATOM   13684 O OD2 . ASP E 1 333 ? 50.189  -4.459  87.675  1.00 44.56  ? 352 ASP E OD2 1 
ATOM   13685 N N   . LYS E 1 334 ? 51.694  -9.680  89.248  1.00 40.29  ? 353 LYS E N   1 
ATOM   13686 C CA  . LYS E 1 334 ? 51.568  -11.033 88.803  1.00 41.79  ? 353 LYS E CA  1 
ATOM   13687 C C   . LYS E 1 334 ? 51.230  -11.986 89.945  1.00 40.89  ? 353 LYS E C   1 
ATOM   13688 O O   . LYS E 1 334 ? 51.688  -11.810 91.075  1.00 39.16  ? 353 LYS E O   1 
ATOM   13689 C CB  . LYS E 1 334 ? 52.890  -11.428 88.171  1.00 42.28  ? 353 LYS E CB  1 
ATOM   13690 C CG  . LYS E 1 334 ? 53.178  -10.679 86.900  1.00 44.23  ? 353 LYS E CG  1 
ATOM   13691 C CD  . LYS E 1 334 ? 54.463  -11.223 86.264  1.00 45.31  ? 353 LYS E CD  1 
ATOM   13692 C CE  . LYS E 1 334 ? 54.970  -10.291 85.156  1.00 47.13  ? 353 LYS E CE  1 
ATOM   13693 N NZ  . LYS E 1 334 ? 54.235  -10.580 83.867  1.00 50.24  ? 353 LYS E NZ  1 
ATOM   13694 N N   . PRO E 1 335 ? 50.428  -13.007 89.680  1.00 41.77  ? 354 PRO E N   1 
ATOM   13695 C CA  . PRO E 1 335 ? 50.230  -14.057 90.678  1.00 41.40  ? 354 PRO E CA  1 
ATOM   13696 C C   . PRO E 1 335 ? 51.546  -14.666 91.134  1.00 40.26  ? 354 PRO E C   1 
ATOM   13697 O O   . PRO E 1 335 ? 52.380  -15.091 90.328  1.00 40.64  ? 354 PRO E O   1 
ATOM   13698 C CB  . PRO E 1 335 ? 49.366  -15.073 89.937  1.00 44.08  ? 354 PRO E CB  1 
ATOM   13699 C CG  . PRO E 1 335 ? 48.633  -14.240 88.970  1.00 45.43  ? 354 PRO E CG  1 
ATOM   13700 C CD  . PRO E 1 335 ? 49.610  -13.245 88.477  1.00 44.04  ? 354 PRO E CD  1 
ATOM   13701 N N   . LEU E 1 336 ? 51.716  -14.678 92.456  1.00 42.70  ? 355 LEU E N   1 
ATOM   13702 C CA  . LEU E 1 336 ? 52.864  -15.296 93.122  1.00 41.63  ? 355 LEU E CA  1 
ATOM   13703 C C   . LEU E 1 336 ? 52.377  -16.578 93.788  1.00 42.71  ? 355 LEU E C   1 
ATOM   13704 O O   . LEU E 1 336 ? 52.760  -17.675 93.366  1.00 44.14  ? 355 LEU E O   1 
ATOM   13705 C CB  . LEU E 1 336 ? 53.454  -14.335 94.141  1.00 39.70  ? 355 LEU E CB  1 
ATOM   13706 C CG  . LEU E 1 336 ? 54.648  -14.864 94.912  1.00 38.65  ? 355 LEU E CG  1 
ATOM   13707 C CD1 . LEU E 1 336 ? 55.878  -15.048 94.010  1.00 38.65  ? 355 LEU E CD1 1 
ATOM   13708 C CD2 . LEU E 1 336 ? 55.012  -13.924 96.082  1.00 36.90  ? 355 LEU E CD2 1 
ATOM   13709 N N   . GLY E 1 337 ? 51.523  -16.464 94.811  1.00 41.33  ? 356 GLY E N   1 
ATOM   13710 C CA  . GLY E 1 337 ? 51.000  -17.599 95.530  1.00 43.30  ? 356 GLY E CA  1 
ATOM   13711 C C   . GLY E 1 337 ? 51.940  -18.117 96.607  1.00 42.86  ? 356 GLY E C   1 
ATOM   13712 O O   . GLY E 1 337 ? 53.134  -17.756 96.703  1.00 41.10  ? 356 GLY E O   1 
ATOM   13713 N N   . LYS E 1 338 ? 51.389  -19.009 97.428  1.00 43.64  ? 357 LYS E N   1 
ATOM   13714 C CA  . LYS E 1 338 ? 52.140  -19.566 98.541  1.00 43.63  ? 357 LYS E CA  1 
ATOM   13715 C C   . LYS E 1 338 ? 53.443  -20.187 98.056  1.00 43.37  ? 357 LYS E C   1 
ATOM   13716 O O   . LYS E 1 338 ? 53.518  -20.694 96.939  1.00 44.31  ? 357 LYS E O   1 
ATOM   13717 C CB  . LYS E 1 338 ? 51.331  -20.634 99.261  1.00 46.93  ? 357 LYS E CB  1 
ATOM   13718 C CG  . LYS E 1 338 ? 50.005  -20.153 99.754  1.00 48.69  ? 357 LYS E CG  1 
ATOM   13719 C CD  . LYS E 1 338 ? 49.258  -21.233 100.500 1.00 53.25  ? 357 LYS E CD  1 
ATOM   13720 C CE  . LYS E 1 338 ? 49.456  -22.674 99.929  1.00 55.15  ? 357 LYS E CE  1 
ATOM   13721 N NZ  . LYS E 1 338 ? 48.632  -22.973 98.681  1.00 58.68  ? 357 LYS E NZ  1 
ATOM   13722 N N   . PRO E 1 339 ? 54.486  -20.157 98.874  1.00 43.78  ? 358 PRO E N   1 
ATOM   13723 C CA  . PRO E 1 339 ? 55.650  -20.979 98.576  1.00 44.44  ? 358 PRO E CA  1 
ATOM   13724 C C   . PRO E 1 339 ? 55.256  -22.433 98.659  1.00 47.25  ? 358 PRO E C   1 
ATOM   13725 O O   . PRO E 1 339 ? 54.428  -22.836 99.482  1.00 48.71  ? 358 PRO E O   1 
ATOM   13726 C CB  . PRO E 1 339 ? 56.658  -20.608 99.667  1.00 43.60  ? 358 PRO E CB  1 
ATOM   13727 C CG  . PRO E 1 339 ? 56.175  -19.420 100.300 1.00 42.23  ? 358 PRO E CG  1 
ATOM   13728 C CD  . PRO E 1 339 ? 54.686  -19.355 100.096 1.00 42.52  ? 358 PRO E CD  1 
ATOM   13729 N N   . VAL E 1 340 ? 55.836  -23.226 97.774  1.00 45.54  ? 359 VAL E N   1 
ATOM   13730 C CA  . VAL E 1 340 ? 55.573  -24.660 97.777  1.00 49.88  ? 359 VAL E CA  1 
ATOM   13731 C C   . VAL E 1 340 ? 56.791  -25.458 98.175  1.00 50.32  ? 359 VAL E C   1 
ATOM   13732 O O   . VAL E 1 340 ? 56.686  -26.672 98.312  1.00 54.20  ? 359 VAL E O   1 
ATOM   13733 C CB  . VAL E 1 340 ? 55.029  -25.131 96.417  1.00 52.23  ? 359 VAL E CB  1 
ATOM   13734 C CG1 . VAL E 1 340 ? 53.847  -24.250 96.044  1.00 51.91  ? 359 VAL E CG1 1 
ATOM   13735 C CG2 . VAL E 1 340 ? 56.103  -25.055 95.357  1.00 50.38  ? 359 VAL E CG2 1 
ATOM   13736 N N   . GLY E 1 341 ? 57.943  -24.813 98.361  1.00 47.01  ? 360 GLY E N   1 
ATOM   13737 C CA  . GLY E 1 341 ? 59.098  -25.422 99.000  1.00 47.50  ? 360 GLY E CA  1 
ATOM   13738 C C   . GLY E 1 341 ? 60.015  -24.374 99.599  1.00 44.69  ? 360 GLY E C   1 
ATOM   13739 O O   . GLY E 1 341 ? 59.907  -23.166 99.300  1.00 42.40  ? 360 GLY E O   1 
ATOM   13740 N N   . GLU E 1 342 ? 60.920  -24.840 100.468 1.00 46.27  ? 361 GLU E N   1 
ATOM   13741 C CA  . GLU E 1 342 ? 61.871  -23.923 101.086 1.00 44.40  ? 361 GLU E CA  1 
ATOM   13742 C C   . GLU E 1 342 ? 62.955  -23.507 100.081 1.00 42.99  ? 361 GLU E C   1 
ATOM   13743 O O   . GLU E 1 342 ? 63.164  -24.150 99.047  1.00 43.78  ? 361 GLU E O   1 
ATOM   13744 C CB  . GLU E 1 342 ? 62.514  -24.541 102.336 1.00 45.86  ? 361 GLU E CB  1 
ATOM   13745 C CG  . GLU E 1 342 ? 61.535  -25.074 103.397 1.00 47.55  ? 361 GLU E CG  1 
ATOM   13746 C CD  . GLU E 1 342 ? 60.630  -24.035 104.084 1.00 46.12  ? 361 GLU E CD  1 
ATOM   13747 O OE1 . GLU E 1 342 ? 60.550  -22.850 103.631 1.00 43.71  ? 361 GLU E OE1 1 
ATOM   13748 O OE2 . GLU E 1 342 ? 59.964  -24.416 105.080 1.00 47.64  ? 361 GLU E OE2 1 
ATOM   13749 N N   . MET E 1 343 ? 63.619  -22.384 100.369 1.00 41.39  ? 362 MET E N   1 
ATOM   13750 C CA  . MET E 1 343 ? 64.761  -21.983 99.565  1.00 40.92  ? 362 MET E CA  1 
ATOM   13751 C C   . MET E 1 343 ? 65.710  -23.168 99.492  1.00 43.74  ? 362 MET E C   1 
ATOM   13752 O O   . MET E 1 343 ? 66.017  -23.796 100.512 1.00 45.07  ? 362 MET E O   1 
ATOM   13753 C CB  . MET E 1 343 ? 65.475  -20.759 100.160 1.00 38.13  ? 362 MET E CB  1 
ATOM   13754 N N   . VAL E 1 344 ? 66.155  -23.475 98.282  1.00 41.94  ? 363 VAL E N   1 
ATOM   13755 C CA  . VAL E 1 344 ? 67.245  -24.412 98.055  1.00 43.60  ? 363 VAL E CA  1 
ATOM   13756 C C   . VAL E 1 344 ? 68.484  -23.632 97.653  1.00 42.16  ? 363 VAL E C   1 
ATOM   13757 O O   . VAL E 1 344 ? 68.425  -22.757 96.796  1.00 40.54  ? 363 VAL E O   1 
ATOM   13758 C CB  . VAL E 1 344 ? 66.884  -25.452 96.959  1.00 46.26  ? 363 VAL E CB  1 
ATOM   13759 C CG1 . VAL E 1 344 ? 68.098  -26.264 96.594  1.00 48.07  ? 363 VAL E CG1 1 
ATOM   13760 C CG2 . VAL E 1 344 ? 65.750  -26.292 97.428  1.00 47.28  ? 363 VAL E CG2 1 
ATOM   13761 N N   . ARG E 1 345 ? 69.615  -23.987 98.233  1.00 46.84  ? 364 ARG E N   1 
ATOM   13762 C CA  . ARG E 1 345 ? 70.889  -23.368 97.910  1.00 45.58  ? 364 ARG E CA  1 
ATOM   13763 C C   . ARG E 1 345 ? 71.863  -24.421 97.411  1.00 47.74  ? 364 ARG E C   1 
ATOM   13764 O O   . ARG E 1 345 ? 71.808  -25.561 97.836  1.00 50.02  ? 364 ARG E O   1 
ATOM   13765 C CB  . ARG E 1 345 ? 71.478  -22.701 99.126  1.00 44.54  ? 364 ARG E CB  1 
ATOM   13766 C CG  . ARG E 1 345 ? 72.807  -22.041 98.894  1.00 44.14  ? 364 ARG E CG  1 
ATOM   13767 C CD  . ARG E 1 345 ? 73.039  -21.179 100.095 1.00 43.14  ? 364 ARG E CD  1 
ATOM   13768 N NE  . ARG E 1 345 ? 74.433  -20.952 100.365 1.00 43.65  ? 364 ARG E NE  1 
ATOM   13769 C CZ  . ARG E 1 345 ? 75.329  -21.887 100.579 1.00 45.57  ? 364 ARG E CZ  1 
ATOM   13770 N NH1 . ARG E 1 345 ? 74.998  -23.175 100.612 1.00 47.33  ? 364 ARG E NH1 1 
ATOM   13771 N NH2 . ARG E 1 345 ? 76.599  -21.524 100.771 1.00 45.60  ? 364 ARG E NH2 1 
ATOM   13772 N N   . ASP E 1 346 ? 72.740  -24.028 96.491  1.00 45.11  ? 365 ASP E N   1 
ATOM   13773 C CA  . ASP E 1 346 ? 73.883  -24.836 96.063  1.00 47.09  ? 365 ASP E CA  1 
ATOM   13774 C C   . ASP E 1 346 ? 74.950  -23.784 95.741  1.00 45.95  ? 365 ASP E C   1 
ATOM   13775 O O   . ASP E 1 346 ? 74.915  -23.175 94.662  1.00 44.85  ? 365 ASP E O   1 
ATOM   13776 C CB  . ASP E 1 346 ? 73.590  -25.736 94.865  1.00 48.47  ? 365 ASP E CB  1 
ATOM   13777 C CG  . ASP E 1 346 ? 72.856  -27.070 95.256  1.00 50.68  ? 365 ASP E CG  1 
ATOM   13778 O OD1 . ASP E 1 346 ? 73.494  -28.104 95.637  1.00 53.09  ? 365 ASP E OD1 1 
ATOM   13779 O OD2 . ASP E 1 346 ? 71.600  -27.086 95.142  1.00 51.47  ? 365 ASP E OD2 1 
ATOM   13780 N N   . GLY E 1 347 ? 75.841  -23.518 96.698  1.00 45.93  ? 366 GLY E N   1 
ATOM   13781 C CA  . GLY E 1 347 ? 76.907  -22.567 96.488  1.00 45.11  ? 366 GLY E CA  1 
ATOM   13782 C C   . GLY E 1 347 ? 76.415  -21.145 96.569  1.00 42.58  ? 366 GLY E C   1 
ATOM   13783 O O   . GLY E 1 347 ? 75.888  -20.735 97.604  1.00 41.68  ? 366 GLY E O   1 
ATOM   13784 N N   . TRP E 1 348 ? 76.580  -20.393 95.479  1.00 45.85  ? 367 TRP E N   1 
ATOM   13785 C CA  . TRP E 1 348 ? 76.039  -19.045 95.354  1.00 43.47  ? 367 TRP E CA  1 
ATOM   13786 C C   . TRP E 1 348 ? 74.754  -18.974 94.518  1.00 43.14  ? 367 TRP E C   1 
ATOM   13787 O O   . TRP E 1 348 ? 74.281  -17.872 94.194  1.00 41.28  ? 367 TRP E O   1 
ATOM   13788 C CB  . TRP E 1 348 ? 77.070  -18.142 94.720  1.00 43.15  ? 367 TRP E CB  1 
ATOM   13789 C CG  . TRP E 1 348 ? 78.345  -18.058 95.481  1.00 43.45  ? 367 TRP E CG  1 
ATOM   13790 C CD1 . TRP E 1 348 ? 79.599  -18.378 95.021  1.00 45.10  ? 367 TRP E CD1 1 
ATOM   13791 C CD2 . TRP E 1 348 ? 78.518  -17.584 96.828  1.00 42.70  ? 367 TRP E CD2 1 
ATOM   13792 N NE1 . TRP E 1 348 ? 80.530  -18.122 95.995  1.00 45.30  ? 367 TRP E NE1 1 
ATOM   13793 C CE2 . TRP E 1 348 ? 79.898  -17.645 97.116  1.00 43.78  ? 367 TRP E CE2 1 
ATOM   13794 C CE3 . TRP E 1 348 ? 77.641  -17.112 97.817  1.00 41.31  ? 367 TRP E CE3 1 
ATOM   13795 C CZ2 . TRP E 1 348 ? 80.420  -17.244 98.350  1.00 44.25  ? 367 TRP E CZ2 1 
ATOM   13796 C CZ3 . TRP E 1 348 ? 78.165  -16.716 99.044  1.00 41.55  ? 367 TRP E CZ3 1 
ATOM   13797 C CH2 . TRP E 1 348 ? 79.539  -16.783 99.297  1.00 43.16  ? 367 TRP E CH2 1 
ATOM   13798 N N   . LYS E 1 349 ? 74.207  -20.133 94.147  1.00 41.46  ? 368 LYS E N   1 
ATOM   13799 C CA  . LYS E 1 349 ? 72.989  -20.271 93.364  1.00 42.02  ? 368 LYS E CA  1 
ATOM   13800 C C   . LYS E 1 349 ? 71.870  -20.582 94.344  1.00 41.29  ? 368 LYS E C   1 
ATOM   13801 O O   . LYS E 1 349 ? 72.070  -21.371 95.276  1.00 42.44  ? 368 LYS E O   1 
ATOM   13802 C CB  . LYS E 1 349 ? 73.189  -21.364 92.314  1.00 45.46  ? 368 LYS E CB  1 
ATOM   13803 C CG  . LYS E 1 349 ? 74.199  -20.966 91.217  1.00 46.69  ? 368 LYS E CG  1 
ATOM   13804 C CD  . LYS E 1 349 ? 74.847  -22.126 90.452  1.00 50.22  ? 368 LYS E CD  1 
ATOM   13805 C CE  . LYS E 1 349 ? 75.639  -23.162 91.359  1.00 52.14  ? 368 LYS E CE  1 
ATOM   13806 N NZ  . LYS E 1 349 ? 76.870  -23.850 90.726  1.00 54.20  ? 368 LYS E NZ  1 
ATOM   13807 N N   . LEU E 1 350 ? 70.717  -19.914 94.174  1.00 41.24  ? 369 LEU E N   1 
ATOM   13808 C CA  . LEU E 1 350 ? 69.583  -20.056 95.074  1.00 40.81  ? 369 LEU E CA  1 
ATOM   13809 C C   . LEU E 1 350 ? 68.339  -20.283 94.251  1.00 42.49  ? 369 LEU E C   1 
ATOM   13810 O O   . LEU E 1 350 ? 68.224  -19.713 93.170  1.00 42.50  ? 369 LEU E O   1 
ATOM   13811 C CB  . LEU E 1 350 ? 69.298  -18.836 95.920  1.00 38.42  ? 369 LEU E CB  1 
ATOM   13812 C CG  . LEU E 1 350 ? 70.426  -18.283 96.777  1.00 37.40  ? 369 LEU E CG  1 
ATOM   13813 C CD1 . LEU E 1 350 ? 70.065  -16.925 97.357  1.00 35.35  ? 369 LEU E CD1 1 
ATOM   13814 C CD2 . LEU E 1 350 ? 70.759  -19.276 97.870  1.00 38.88  ? 369 LEU E CD2 1 
ATOM   13815 N N   . SER E 1 351 ? 67.387  -21.065 94.778  1.00 40.41  ? 370 SER E N   1 
ATOM   13816 C CA  . SER E 1 351 ? 66.135  -21.282 94.072  1.00 41.65  ? 370 SER E CA  1 
ATOM   13817 C C   . SER E 1 351 ? 64.972  -21.393 95.044  1.00 40.38  ? 370 SER E C   1 
ATOM   13818 O O   . SER E 1 351 ? 65.133  -21.796 96.206  1.00 40.51  ? 370 SER E O   1 
ATOM   13819 C CB  . SER E 1 351 ? 66.173  -22.523 93.193  1.00 44.87  ? 370 SER E CB  1 
ATOM   13820 O OG  . SER E 1 351 ? 66.363  -23.703 93.971  1.00 46.94  ? 370 SER E OG  1 
ATOM   13821 N N   . ARG E 1 352 ? 63.794  -20.998 94.542  1.00 43.54  ? 371 ARG E N   1 
ATOM   13822 C CA  . ARG E 1 352 ? 62.544  -21.075 95.283  1.00 42.85  ? 371 ARG E CA  1 
ATOM   13823 C C   . ARG E 1 352 ? 61.397  -21.326 94.310  1.00 43.52  ? 371 ARG E C   1 
ATOM   13824 O O   . ARG E 1 352 ? 61.376  -20.763 93.205  1.00 43.56  ? 371 ARG E O   1 
ATOM   13825 C CB  . ARG E 1 352 ? 62.252  -19.802 96.080  1.00 40.57  ? 371 ARG E CB  1 
ATOM   13826 C CG  . ARG E 1 352 ? 61.164  -19.944 97.123  1.00 39.85  ? 371 ARG E CG  1 
ATOM   13827 C CD  . ARG E 1 352 ? 61.695  -20.598 98.366  1.00 40.79  ? 371 ARG E CD  1 
ATOM   13828 N NE  . ARG E 1 352 ? 60.711  -20.543 99.446  1.00 40.26  ? 371 ARG E NE  1 
ATOM   13829 C CZ  . ARG E 1 352 ? 60.506  -19.482 100.223 1.00 38.68  ? 371 ARG E CZ  1 
ATOM   13830 N NH1 . ARG E 1 352 ? 61.234  -18.379 100.088 1.00 36.79  ? 371 ARG E NH1 1 
ATOM   13831 N NH2 . ARG E 1 352 ? 59.553  -19.536 101.164 1.00 39.43  ? 371 ARG E NH2 1 
ATOM   13832 N N   . GLU E 1 353 ? 60.453  -22.169 94.755  1.00 43.02  ? 372 GLU E N   1 
ATOM   13833 C CA  . GLU E 1 353 ? 59.226  -22.488 94.053  1.00 44.27  ? 372 GLU E CA  1 
ATOM   13834 C C   . GLU E 1 353 ? 58.027  -21.871 94.774  1.00 43.82  ? 372 GLU E C   1 
ATOM   13835 O O   . GLU E 1 353 ? 57.908  -21.961 96.005  1.00 43.95  ? 372 GLU E O   1 
ATOM   13836 C CB  . GLU E 1 353 ? 59.054  -24.015 93.943  1.00 47.27  ? 372 GLU E CB  1 
ATOM   13837 C CG  . GLU E 1 353 ? 60.140  -24.675 93.100  1.00 49.36  ? 372 GLU E CG  1 
ATOM   13838 C CD  . GLU E 1 353 ? 60.213  -24.071 91.685  1.00 50.12  ? 372 GLU E CD  1 
ATOM   13839 O OE1 . GLU E 1 353 ? 59.141  -23.647 91.167  1.00 49.59  ? 372 GLU E OE1 1 
ATOM   13840 O OE2 . GLU E 1 353 ? 61.330  -24.002 91.106  1.00 51.42  ? 372 GLU E OE2 1 
ATOM   13841 N N   . TYR E 1 354 ? 57.132  -21.273 93.979  1.00 44.91  ? 373 TYR E N   1 
ATOM   13842 C CA  . TYR E 1 354 ? 55.905  -20.642 94.427  1.00 44.38  ? 373 TYR E CA  1 
ATOM   13843 C C   . TYR E 1 354 ? 54.765  -21.179 93.589  1.00 46.25  ? 373 TYR E C   1 
ATOM   13844 O O   . TYR E 1 354 ? 54.976  -21.564 92.447  1.00 47.91  ? 373 TYR E O   1 
ATOM   13845 C CB  . TYR E 1 354 ? 55.970  -19.117 94.243  1.00 42.32  ? 373 TYR E CB  1 
ATOM   13846 C CG  . TYR E 1 354 ? 56.839  -18.402 95.216  1.00 40.10  ? 373 TYR E CG  1 
ATOM   13847 C CD1 . TYR E 1 354 ? 58.205  -18.266 94.990  1.00 39.59  ? 373 TYR E CD1 1 
ATOM   13848 C CD2 . TYR E 1 354 ? 56.297  -17.883 96.371  1.00 39.18  ? 373 TYR E CD2 1 
ATOM   13849 C CE1 . TYR E 1 354 ? 58.997  -17.607 95.896  1.00 38.06  ? 373 TYR E CE1 1 
ATOM   13850 C CE2 . TYR E 1 354 ? 57.062  -17.234 97.279  1.00 37.77  ? 373 TYR E CE2 1 
ATOM   13851 C CZ  . TYR E 1 354 ? 58.401  -17.089 97.037  1.00 36.98  ? 373 TYR E CZ  1 
ATOM   13852 O OH  . TYR E 1 354 ? 59.102  -16.428 97.976  1.00 35.62  ? 373 TYR E OH  1 
ATOM   13853 N N   . LYS E 1 355 ? 53.555  -21.168 94.146  1.00 43.73  ? 374 LYS E N   1 
ATOM   13854 C CA  . LYS E 1 355 ? 52.394  -21.674 93.425  1.00 45.04  ? 374 LYS E CA  1 
ATOM   13855 C C   . LYS E 1 355 ? 52.323  -21.194 91.971  1.00 46.09  ? 374 LYS E C   1 
ATOM   13856 O O   . LYS E 1 355 ? 51.873  -21.941 91.096  1.00 47.89  ? 374 LYS E O   1 
ATOM   13857 C CB  . LYS E 1 355 ? 51.130  -21.271 94.182  1.00 44.63  ? 374 LYS E CB  1 
ATOM   13858 C CG  . LYS E 1 355 ? 49.834  -21.841 93.650  1.00 46.84  ? 374 LYS E CG  1 
ATOM   13859 C CD  . LYS E 1 355 ? 48.838  -22.054 94.791  1.00 47.16  ? 374 LYS E CD  1 
ATOM   13860 C CE  . LYS E 1 355 ? 47.549  -22.768 94.316  1.00 48.67  ? 374 LYS E CE  1 
ATOM   13861 N NZ  . LYS E 1 355 ? 47.646  -24.306 94.420  1.00 50.94  ? 374 LYS E NZ  1 
ATOM   13862 N N   . HIS E 1 356 ? 52.747  -19.949 91.679  1.00 44.06  ? 375 HIS E N   1 
ATOM   13863 C CA  . HIS E 1 356 ? 52.656  -19.454 90.303  1.00 45.52  ? 375 HIS E CA  1 
ATOM   13864 C C   . HIS E 1 356 ? 53.984  -18.935 89.758  1.00 46.68  ? 375 HIS E C   1 
ATOM   13865 O O   . HIS E 1 356 ? 53.977  -18.210 88.746  1.00 47.89  ? 375 HIS E O   1 
ATOM   13866 C CB  . HIS E 1 356 ? 51.610  -18.337 90.157  1.00 44.34  ? 375 HIS E CB  1 
ATOM   13867 C CG  . HIS E 1 356 ? 50.267  -18.730 90.660  1.00 43.46  ? 375 HIS E CG  1 
ATOM   13868 N ND1 . HIS E 1 356 ? 49.529  -19.750 90.084  1.00 45.22  ? 375 HIS E ND1 1 
ATOM   13869 C CD2 . HIS E 1 356 ? 49.551  -18.294 91.721  1.00 41.96  ? 375 HIS E CD2 1 
ATOM   13870 C CE1 . HIS E 1 356 ? 48.406  -19.903 90.761  1.00 43.91  ? 375 HIS E CE1 1 
ATOM   13871 N NE2 . HIS E 1 356 ? 48.396  -19.028 91.754  1.00 42.46  ? 375 HIS E NE2 1 
ATOM   13872 N N   . ALA E 1 357 ? 55.108  -19.295 90.373  1.00 42.83  ? 376 ALA E N   1 
ATOM   13873 C CA  . ALA E 1 357 ? 56.377  -18.740 89.905  1.00 44.02  ? 376 ALA E CA  1 
ATOM   13874 C C   . ALA E 1 357 ? 57.552  -19.603 90.361  1.00 44.93  ? 376 ALA E C   1 
ATOM   13875 O O   . ALA E 1 357 ? 57.518  -20.220 91.425  1.00 43.86  ? 376 ALA E O   1 
ATOM   13876 C CB  . ALA E 1 357 ? 56.582  -17.286 90.398  1.00 42.96  ? 376 ALA E CB  1 
ATOM   13877 N N   . SER E 1 358 ? 58.601  -19.598 89.553  1.00 42.35  ? 377 SER E N   1 
ATOM   13878 C CA  . SER E 1 358 ? 59.839  -20.287 89.845  1.00 42.72  ? 377 SER E CA  1 
ATOM   13879 C C   . SER E 1 358 ? 60.954  -19.259 89.847  1.00 42.01  ? 377 SER E C   1 
ATOM   13880 O O   . SER E 1 358 ? 61.102  -18.517 88.879  1.00 43.94  ? 377 SER E O   1 
ATOM   13881 C CB  . SER E 1 358 ? 60.129  -21.374 88.795  1.00 46.50  ? 377 SER E CB  1 
ATOM   13882 O OG  . SER E 1 358 ? 59.103  -22.345 88.739  1.00 49.12  ? 377 SER E OG  1 
ATOM   13883 N N   . VAL E 1 359 ? 61.752  -19.229 90.900  1.00 42.37  ? 378 VAL E N   1 
ATOM   13884 C CA  . VAL E 1 359 ? 62.772  -18.206 91.069  1.00 41.50  ? 378 VAL E CA  1 
ATOM   13885 C C   . VAL E 1 359 ? 64.132  -18.877 91.109  1.00 42.12  ? 378 VAL E C   1 
ATOM   13886 O O   . VAL E 1 359 ? 64.294  -19.896 91.785  1.00 41.58  ? 378 VAL E O   1 
ATOM   13887 C CB  . VAL E 1 359 ? 62.541  -17.387 92.360  1.00 38.88  ? 378 VAL E CB  1 
ATOM   13888 C CG1 . VAL E 1 359 ? 63.611  -16.340 92.488  1.00 38.05  ? 378 VAL E CG1 1 
ATOM   13889 C CG2 . VAL E 1 359 ? 61.138  -16.786 92.404  1.00 38.87  ? 378 VAL E CG2 1 
ATOM   13890 N N   . ARG E 1 360 ? 65.103  -18.300 90.391  1.00 41.00  ? 379 ARG E N   1 
ATOM   13891 C CA  . ARG E 1 360 ? 66.493  -18.744 90.385  1.00 41.86  ? 379 ARG E CA  1 
ATOM   13892 C C   . ARG E 1 360 ? 67.399  -17.513 90.412  1.00 40.39  ? 379 ARG E C   1 
ATOM   13893 O O   . ARG E 1 360 ? 67.194  -16.568 89.641  1.00 41.06  ? 379 ARG E O   1 
ATOM   13894 C CB  . ARG E 1 360 ? 66.824  -19.604 89.150  1.00 46.53  ? 379 ARG E CB  1 
ATOM   13895 C CG  . ARG E 1 360 ? 66.613  -21.131 89.324  1.00 49.93  ? 379 ARG E CG  1 
ATOM   13896 C CD  . ARG E 1 360 ? 66.484  -21.914 88.013  1.00 53.21  ? 379 ARG E CD  1 
ATOM   13897 N NE  . ARG E 1 360 ? 67.533  -21.700 87.009  1.00 56.71  ? 379 ARG E NE  1 
ATOM   13898 C CZ  . ARG E 1 360 ? 68.828  -21.997 87.145  1.00 58.22  ? 379 ARG E CZ  1 
ATOM   13899 N NH1 . ARG E 1 360 ? 69.333  -22.378 88.312  1.00 56.77  ? 379 ARG E NH1 1 
ATOM   13900 N NH2 . ARG E 1 360 ? 69.641  -21.916 86.079  1.00 60.98  ? 379 ARG E NH2 1 
ATOM   13901 N N   . VAL E 1 361 ? 68.413  -17.528 91.277  1.00 41.68  ? 380 VAL E N   1 
ATOM   13902 C CA  . VAL E 1 361 ? 69.355  -16.419 91.357  1.00 41.13  ? 380 VAL E CA  1 
ATOM   13903 C C   . VAL E 1 361 ? 70.754  -16.943 91.620  1.00 41.18  ? 380 VAL E C   1 
ATOM   13904 O O   . VAL E 1 361 ? 70.925  -17.901 92.371  1.00 41.35  ? 380 VAL E O   1 
ATOM   13905 C CB  . VAL E 1 361 ? 68.904  -15.394 92.417  1.00 39.74  ? 380 VAL E CB  1 
ATOM   13906 C CG1 . VAL E 1 361 ? 68.790  -16.003 93.779  1.00 38.21  ? 380 VAL E CG1 1 
ATOM   13907 C CG2 . VAL E 1 361 ? 69.876  -14.251 92.485  1.00 39.70  ? 380 VAL E CG2 1 
ATOM   13908 N N   . ASP E 1 362 ? 71.754  -16.315 90.991  1.00 41.48  ? 381 ASP E N   1 
ATOM   13909 C CA  . ASP E 1 362 ? 73.190  -16.556 91.237  1.00 41.58  ? 381 ASP E CA  1 
ATOM   13910 C C   . ASP E 1 362 ? 73.800  -15.289 91.870  1.00 39.74  ? 381 ASP E C   1 
ATOM   13911 O O   . ASP E 1 362 ? 73.972  -14.252 91.204  1.00 40.56  ? 381 ASP E O   1 
ATOM   13912 C CB  . ASP E 1 362 ? 73.911  -16.916 89.933  1.00 44.76  ? 381 ASP E CB  1 
ATOM   13913 C CG  . ASP E 1 362 ? 75.391  -17.379 90.136  1.00 45.88  ? 381 ASP E CG  1 
ATOM   13914 O OD1 . ASP E 1 362 ? 76.114  -16.903 91.061  1.00 44.20  ? 381 ASP E OD1 1 
ATOM   13915 O OD2 . ASP E 1 362 ? 75.860  -18.228 89.334  1.00 49.05  ? 381 ASP E OD2 1 
ATOM   13916 N N   . LEU E 1 363 ? 74.115  -15.379 93.162  1.00 41.74  ? 382 LEU E N   1 
ATOM   13917 C CA  . LEU E 1 363 ? 74.685  -14.250 93.882  1.00 41.12  ? 382 LEU E CA  1 
ATOM   13918 C C   . LEU E 1 363 ? 76.077  -13.888 93.383  1.00 42.39  ? 382 LEU E C   1 
ATOM   13919 O O   . LEU E 1 363 ? 76.532  -12.765 93.615  1.00 42.33  ? 382 LEU E O   1 
ATOM   13920 C CB  . LEU E 1 363 ? 74.731  -14.568 95.382  1.00 40.62  ? 382 LEU E CB  1 
ATOM   13921 C CG  . LEU E 1 363 ? 73.387  -14.880 96.031  1.00 39.72  ? 382 LEU E CG  1 
ATOM   13922 C CD1 . LEU E 1 363 ? 73.500  -15.177 97.507  1.00 40.24  ? 382 LEU E CD1 1 
ATOM   13923 C CD2 . LEU E 1 363 ? 72.381  -13.739 95.904  1.00 38.89  ? 382 LEU E CD2 1 
ATOM   13924 N N   . GLU E 1 364 ? 76.784  -14.794 92.732  1.00 40.35  ? 383 GLU E N   1 
ATOM   13925 C CA  . GLU E 1 364 ? 78.148  -14.494 92.332  1.00 41.75  ? 383 GLU E CA  1 
ATOM   13926 C C   . GLU E 1 364 ? 78.202  -13.817 90.969  1.00 42.52  ? 383 GLU E C   1 
ATOM   13927 O O   . GLU E 1 364 ? 79.040  -12.936 90.747  1.00 43.10  ? 383 GLU E O   1 
ATOM   13928 C CB  . GLU E 1 364 ? 78.962  -15.780 92.314  1.00 42.91  ? 383 GLU E CB  1 
ATOM   13929 C CG  . GLU E 1 364 ? 80.281  -15.681 91.654  1.00 45.16  ? 383 GLU E CG  1 
ATOM   13930 C CD  . GLU E 1 364 ? 81.106  -16.975 91.784  1.00 47.50  ? 383 GLU E CD  1 
ATOM   13931 O OE1 . GLU E 1 364 ? 80.500  -18.088 91.844  1.00 47.05  ? 383 GLU E OE1 1 
ATOM   13932 O OE2 . GLU E 1 364 ? 82.373  -16.868 91.825  1.00 49.73  ? 383 GLU E OE2 1 
ATOM   13933 N N   . SER E 1 365 ? 77.314  -14.190 90.044  1.00 41.86  ? 384 SER E N   1 
ATOM   13934 C CA  . SER E 1 365 ? 77.238  -13.519 88.758  1.00 42.82  ? 384 SER E CA  1 
ATOM   13935 C C   . SER E 1 365 ? 76.191  -12.404 88.728  1.00 41.96  ? 384 SER E C   1 
ATOM   13936 O O   . SER E 1 365 ? 76.132  -11.653 87.745  1.00 43.47  ? 384 SER E O   1 
ATOM   13937 C CB  . SER E 1 365 ? 76.929  -14.525 87.648  1.00 44.69  ? 384 SER E CB  1 
ATOM   13938 O OG  . SER E 1 365 ? 75.666  -15.115 87.866  1.00 43.86  ? 384 SER E OG  1 
ATOM   13939 N N   . LYS E 1 366 ? 75.381  -12.269 89.773  1.00 40.86  ? 385 LYS E N   1 
ATOM   13940 C CA  . LYS E 1 366 ? 74.288  -11.301 89.760  1.00 41.64  ? 385 LYS E CA  1 
ATOM   13941 C C   . LYS E 1 366 ? 73.436  -11.543 88.515  1.00 43.52  ? 385 LYS E C   1 
ATOM   13942 O O   . LYS E 1 366 ? 73.240  -10.654 87.680  1.00 45.46  ? 385 LYS E O   1 
ATOM   13943 C CB  . LYS E 1 366 ? 74.824  -9.858  89.797  1.00 43.49  ? 385 LYS E CB  1 
ATOM   13944 N N   . GLU E 1 367 ? 72.990  -12.800 88.350  1.00 38.12  ? 386 GLU E N   1 
ATOM   13945 C CA  . GLU E 1 367 ? 72.010  -13.171 87.341  1.00 40.22  ? 386 GLU E CA  1 
ATOM   13946 C C   . GLU E 1 367 ? 70.800  -13.735 88.054  1.00 37.99  ? 386 GLU E C   1 
ATOM   13947 O O   . GLU E 1 367 ? 70.895  -14.246 89.166  1.00 36.33  ? 386 GLU E O   1 
ATOM   13948 C CB  . GLU E 1 367 ? 72.563  -14.165 86.352  1.00 43.58  ? 386 GLU E CB  1 
ATOM   13949 C CG  . GLU E 1 367 ? 73.850  -13.713 85.695  1.00 46.81  ? 386 GLU E CG  1 
ATOM   13950 C CD  . GLU E 1 367 ? 74.175  -14.489 84.418  1.00 50.50  ? 386 GLU E CD  1 
ATOM   13951 O OE1 . GLU E 1 367 ? 74.055  -13.939 83.312  1.00 51.93  ? 386 GLU E OE1 1 
ATOM   13952 O OE2 . GLU E 1 367 ? 74.566  -15.682 84.523  1.00 52.13  ? 386 GLU E OE2 1 
ATOM   13953 N N   . ALA E 1 368 ? 69.646  -13.624 87.430  1.00 37.90  ? 387 ALA E N   1 
ATOM   13954 C CA  . ALA E 1 368 ? 68.457  -14.155 88.061  1.00 36.69  ? 387 ALA E CA  1 
ATOM   13955 C C   . ALA E 1 368 ? 67.459  -14.432 86.958  1.00 38.61  ? 387 ALA E C   1 
ATOM   13956 O O   . ALA E 1 368 ? 67.604  -13.946 85.840  1.00 40.75  ? 387 ALA E O   1 
ATOM   13957 C CB  . ALA E 1 368 ? 67.902  -13.192 89.103  1.00 34.65  ? 387 ALA E CB  1 
ATOM   13958 N N   . GLU E 1 369 ? 66.464  -15.263 87.272  1.00 39.21  ? 388 GLU E N   1 
ATOM   13959 C CA  . GLU E 1 369 ? 65.364  -15.542 86.359  1.00 41.71  ? 388 GLU E CA  1 
ATOM   13960 C C   . GLU E 1 369 ? 64.116  -15.663 87.215  1.00 39.11  ? 388 GLU E C   1 
ATOM   13961 O O   . GLU E 1 369 ? 64.151  -16.248 88.300  1.00 36.89  ? 388 GLU E O   1 
ATOM   13962 C CB  . GLU E 1 369 ? 65.577  -16.817 85.532  1.00 45.31  ? 388 GLU E CB  1 
ATOM   13963 N N   . ILE E 1 370 ? 63.017  -15.099 86.751  1.00 42.33  ? 389 ILE E N   1 
ATOM   13964 C CA  . ILE E 1 370 ? 61.742  -15.309 87.400  1.00 41.01  ? 389 ILE E CA  1 
ATOM   13965 C C   . ILE E 1 370 ? 60.791  -15.815 86.338  1.00 43.92  ? 389 ILE E C   1 
ATOM   13966 O O   . ILE E 1 370 ? 60.421  -15.061 85.428  1.00 46.35  ? 389 ILE E O   1 
ATOM   13967 C CB  . ILE E 1 370 ? 61.211  -14.046 88.071  1.00 39.23  ? 389 ILE E CB  1 
ATOM   13968 C CG1 . ILE E 1 370 ? 62.289  -13.515 89.003  1.00 37.41  ? 389 ILE E CG1 1 
ATOM   13969 C CG2 . ILE E 1 370 ? 59.945  -14.365 88.827  1.00 37.64  ? 389 ILE E CG2 1 
ATOM   13970 C CD1 . ILE E 1 370 ? 61.968  -12.210 89.693  1.00 35.83  ? 389 ILE E CD1 1 
ATOM   13971 N N   . ARG E 1 371 ? 60.404  -17.099 86.444  1.00 45.18  ? 390 ARG E N   1 
ATOM   13972 C CA  . ARG E 1 371 ? 59.488  -17.746 85.505  1.00 47.29  ? 390 ARG E CA  1 
ATOM   13973 C C   . ARG E 1 371 ? 58.078  -17.662 86.095  1.00 44.31  ? 390 ARG E C   1 
ATOM   13974 O O   . ARG E 1 371 ? 57.721  -18.440 86.993  1.00 43.35  ? 390 ARG E O   1 
ATOM   13975 C CB  . ARG E 1 371 ? 59.911  -19.187 85.241  1.00 49.49  ? 390 ARG E CB  1 
ATOM   13976 N N   . TRP E 1 372 ? 57.272  -16.716 85.592  1.00 48.30  ? 391 TRP E N   1 
ATOM   13977 C CA  . TRP E 1 372 ? 55.893  -16.570 86.042  1.00 46.25  ? 391 TRP E CA  1 
ATOM   13978 C C   . TRP E 1 372 ? 55.004  -17.563 85.305  1.00 47.39  ? 391 TRP E C   1 
ATOM   13979 O O   . TRP E 1 372 ? 55.287  -17.934 84.161  1.00 49.95  ? 391 TRP E O   1 
ATOM   13980 C CB  . TRP E 1 372 ? 55.402  -15.136 85.816  1.00 45.37  ? 391 TRP E CB  1 
ATOM   13981 C CG  . TRP E 1 372 ? 56.263  -14.087 86.510  1.00 44.48  ? 391 TRP E CG  1 
ATOM   13982 C CD1 . TRP E 1 372 ? 57.322  -13.405 85.977  1.00 46.45  ? 391 TRP E CD1 1 
ATOM   13983 C CD2 . TRP E 1 372 ? 56.145  -13.638 87.861  1.00 41.32  ? 391 TRP E CD2 1 
ATOM   13984 N NE1 . TRP E 1 372 ? 57.856  -12.578 86.906  1.00 44.93  ? 391 TRP E NE1 1 
ATOM   13985 C CE2 . TRP E 1 372 ? 57.151  -12.699 88.074  1.00 41.55  ? 391 TRP E CE2 1 
ATOM   13986 C CE3 . TRP E 1 372 ? 55.294  -13.962 88.917  1.00 38.67  ? 391 TRP E CE3 1 
ATOM   13987 C CZ2 . TRP E 1 372 ? 57.323  -12.054 89.297  1.00 39.15  ? 391 TRP E CZ2 1 
ATOM   13988 C CZ3 . TRP E 1 372 ? 55.453  -13.300 90.131  1.00 36.61  ? 391 TRP E CZ3 1 
ATOM   13989 C CH2 . TRP E 1 372 ? 56.456  -12.363 90.306  1.00 36.87  ? 391 TRP E CH2 1 
ATOM   13990 N N   . ARG E 1 373 ? 53.920  -17.988 85.967  1.00 45.49  ? 392 ARG E N   1 
ATOM   13991 C CA  . ARG E 1 373 ? 53.021  -18.956 85.369  1.00 46.85  ? 392 ARG E CA  1 
ATOM   13992 C C   . ARG E 1 373 ? 51.599  -18.953 85.957  1.00 44.91  ? 392 ARG E C   1 
ATOM   13993 O O   . ARG E 1 373 ? 50.991  -17.888 86.184  1.00 43.32  ? 392 ARG E O   1 
ATOM   13994 C CB  . ARG E 1 373 ? 53.635  -20.358 85.504  1.00 48.94  ? 392 ARG E CB  1 
ATOM   13995 C CG  . ARG E 1 373 ? 53.503  -20.945 86.905  1.00 48.69  ? 392 ARG E CG  1 
ATOM   13996 C CD  . ARG E 1 373 ? 54.517  -22.111 87.192  1.00 50.94  ? 392 ARG E CD  1 
ATOM   13997 N NE  . ARG E 1 373 ? 54.533  -22.467 88.616  1.00 51.23  ? 392 ARG E NE  1 
ATOM   13998 C CZ  . ARG E 1 373 ? 55.629  -22.808 89.288  1.00 52.79  ? 392 ARG E CZ  1 
ATOM   13999 N NH1 . ARG E 1 373 ? 56.801  -22.897 88.689  1.00 54.70  ? 392 ARG E NH1 1 
ATOM   14000 N NH2 . ARG E 1 373 ? 55.543  -23.049 90.597  1.00 52.18  ? 392 ARG E NH2 1 
ATOM   14001 N N   . GLU F 1 18  ? 18.184  -29.621 146.949 1.00 56.10  ? 37  GLU F N   1 
ATOM   14002 C CA  . GLU F 1 18  ? 17.590  -28.672 145.997 1.00 58.22  ? 37  GLU F CA  1 
ATOM   14003 C C   . GLU F 1 18  ? 18.250  -28.732 144.582 1.00 62.16  ? 37  GLU F C   1 
ATOM   14004 O O   . GLU F 1 18  ? 17.820  -28.043 143.651 1.00 62.09  ? 37  GLU F O   1 
ATOM   14005 C CB  . GLU F 1 18  ? 17.668  -27.235 146.552 1.00 57.57  ? 37  GLU F CB  1 
ATOM   14006 N N   . SER F 1 19  ? 19.272  -29.589 144.420 1.00 62.23  ? 38  SER F N   1 
ATOM   14007 C CA  . SER F 1 19  ? 20.107  -29.535 143.221 1.00 65.22  ? 38  SER F CA  1 
ATOM   14008 C C   . SER F 1 19  ? 19.360  -29.983 141.972 1.00 65.37  ? 38  SER F C   1 
ATOM   14009 O O   . SER F 1 19  ? 19.709  -29.541 140.868 1.00 68.22  ? 38  SER F O   1 
ATOM   14010 C CB  . SER F 1 19  ? 21.385  -30.357 143.412 1.00 66.95  ? 38  SER F CB  1 
ATOM   14011 O OG  . SER F 1 19  ? 21.125  -31.730 143.392 1.00 67.31  ? 38  SER F OG  1 
ATOM   14012 N N   . HIS F 1 20  ? 18.319  -30.801 142.093 1.00 61.67  ? 39  HIS F N   1 
ATOM   14013 C CA  . HIS F 1 20  ? 17.505  -31.097 140.914 1.00 61.93  ? 39  HIS F CA  1 
ATOM   14014 C C   . HIS F 1 20  ? 16.325  -30.126 140.741 1.00 59.08  ? 39  HIS F C   1 
ATOM   14015 O O   . HIS F 1 20  ? 15.498  -30.332 139.854 1.00 59.32  ? 39  HIS F O   1 
ATOM   14016 C CB  . HIS F 1 20  ? 17.021  -32.572 140.936 1.00 61.57  ? 39  HIS F CB  1 
ATOM   14017 C CG  . HIS F 1 20  ? 16.081  -32.912 142.061 1.00 58.03  ? 39  HIS F CG  1 
ATOM   14018 N ND1 . HIS F 1 20  ? 16.447  -32.853 143.395 1.00 56.70  ? 39  HIS F ND1 1 
ATOM   14019 C CD2 . HIS F 1 20  ? 14.791  -33.338 142.042 1.00 57.03  ? 39  HIS F CD2 1 
ATOM   14020 C CE1 . HIS F 1 20  ? 15.412  -33.197 144.147 1.00 54.13  ? 39  HIS F CE1 1 
ATOM   14021 N NE2 . HIS F 1 20  ? 14.399  -33.507 143.350 1.00 55.14  ? 39  HIS F NE2 1 
ATOM   14022 N N   . TYR F 1 21  ? 16.254  -29.061 141.525 1.00 58.08  ? 40  TYR F N   1 
ATOM   14023 C CA  . TYR F 1 21  ? 15.184  -28.075 141.398 1.00 55.52  ? 40  TYR F CA  1 
ATOM   14024 C C   . TYR F 1 21  ? 15.433  -27.111 140.230 1.00 59.07  ? 40  TYR F C   1 
ATOM   14025 O O   . TYR F 1 21  ? 16.580  -26.885 139.841 1.00 62.97  ? 40  TYR F O   1 
ATOM   14026 C CB  . TYR F 1 21  ? 15.073  -27.266 142.678 1.00 51.83  ? 40  TYR F CB  1 
ATOM   14027 C CG  . TYR F 1 21  ? 14.416  -27.962 143.839 1.00 48.89  ? 40  TYR F CG  1 
ATOM   14028 C CD1 . TYR F 1 21  ? 14.153  -29.329 143.817 1.00 50.13  ? 40  TYR F CD1 1 
ATOM   14029 C CD2 . TYR F 1 21  ? 14.042  -27.246 144.964 1.00 47.17  ? 40  TYR F CD2 1 
ATOM   14030 C CE1 . TYR F 1 21  ? 13.530  -29.960 144.884 1.00 49.40  ? 40  TYR F CE1 1 
ATOM   14031 C CE2 . TYR F 1 21  ? 13.423  -27.883 146.048 1.00 46.85  ? 40  TYR F CE2 1 
ATOM   14032 C CZ  . TYR F 1 21  ? 13.170  -29.240 145.994 1.00 47.63  ? 40  TYR F CZ  1 
ATOM   14033 O OH  . TYR F 1 21  ? 12.549  -29.847 147.058 1.00 47.66  ? 40  TYR F OH  1 
ATOM   14034 N N   . PRO F 1 22  ? 14.375  -26.535 139.659 1.00 54.74  ? 41  PRO F N   1 
ATOM   14035 C CA  . PRO F 1 22  ? 14.561  -25.420 138.708 1.00 57.83  ? 41  PRO F CA  1 
ATOM   14036 C C   . PRO F 1 22  ? 15.318  -24.269 139.345 1.00 58.40  ? 41  PRO F C   1 
ATOM   14037 O O   . PRO F 1 22  ? 15.065  -23.908 140.495 1.00 54.85  ? 41  PRO F O   1 
ATOM   14038 C CB  . PRO F 1 22  ? 13.134  -24.987 138.359 1.00 55.16  ? 41  PRO F CB  1 
ATOM   14039 C CG  . PRO F 1 22  ? 12.270  -26.077 138.852 1.00 52.99  ? 41  PRO F CG  1 
ATOM   14040 C CD  . PRO F 1 22  ? 12.958  -26.767 139.969 1.00 51.12  ? 41  PRO F CD  1 
ATOM   14041 N N   . GLU F 1 23  ? 16.236  -23.681 138.572 1.00 59.69  ? 42  GLU F N   1 
ATOM   14042 C CA  . GLU F 1 23  ? 17.012  -22.535 139.037 1.00 60.70  ? 42  GLU F CA  1 
ATOM   14043 C C   . GLU F 1 23  ? 16.084  -21.400 139.416 1.00 58.50  ? 42  GLU F C   1 
ATOM   14044 O O   . GLU F 1 23  ? 15.353  -20.867 138.572 1.00 59.89  ? 42  GLU F O   1 
ATOM   14045 C CB  . GLU F 1 23  ? 17.995  -22.058 137.974 1.00 66.13  ? 42  GLU F CB  1 
ATOM   14046 C CG  . GLU F 1 23  ? 19.455  -22.146 138.413 1.00 68.35  ? 42  GLU F CG  1 
ATOM   14047 C CD  . GLU F 1 23  ? 20.444  -21.814 137.293 1.00 73.37  ? 42  GLU F CD  1 
ATOM   14048 O OE1 . GLU F 1 23  ? 20.748  -22.692 136.449 1.00 76.04  ? 42  GLU F OE1 1 
ATOM   14049 O OE2 . GLU F 1 23  ? 20.915  -20.662 137.242 1.00 76.23  ? 42  GLU F OE2 1 
ATOM   14050 N N   . PHE F 1 24  ? 16.120  -21.048 140.690 1.00 63.67  ? 43  PHE F N   1 
ATOM   14051 C CA  . PHE F 1 24  ? 15.226  -20.068 141.271 1.00 59.74  ? 43  PHE F CA  1 
ATOM   14052 C C   . PHE F 1 24  ? 15.941  -18.737 141.445 1.00 62.20  ? 43  PHE F C   1 
ATOM   14053 O O   . PHE F 1 24  ? 17.127  -18.697 141.775 1.00 64.31  ? 43  PHE F O   1 
ATOM   14054 C CB  . PHE F 1 24  ? 14.724  -20.550 142.625 1.00 53.79  ? 43  PHE F CB  1 
ATOM   14055 C CG  . PHE F 1 24  ? 13.812  -19.578 143.298 1.00 48.79  ? 43  PHE F CG  1 
ATOM   14056 C CD1 . PHE F 1 24  ? 12.467  -19.538 142.965 1.00 48.83  ? 43  PHE F CD1 1 
ATOM   14057 C CD2 . PHE F 1 24  ? 14.300  -18.675 144.237 1.00 47.61  ? 43  PHE F CD2 1 
ATOM   14058 C CE1 . PHE F 1 24  ? 11.633  -18.627 143.580 1.00 48.57  ? 43  PHE F CE1 1 
ATOM   14059 C CE2 . PHE F 1 24  ? 13.473  -17.796 144.861 1.00 46.02  ? 43  PHE F CE2 1 
ATOM   14060 C CZ  . PHE F 1 24  ? 12.147  -17.754 144.531 1.00 47.10  ? 43  PHE F CZ  1 
ATOM   14061 N N   . SER F 1 25  ? 15.206  -17.649 141.247 1.00 54.82  ? 44  SER F N   1 
ATOM   14062 C CA  . SER F 1 25  ? 15.778  -16.309 141.287 1.00 56.88  ? 44  SER F CA  1 
ATOM   14063 C C   . SER F 1 25  ? 14.740  -15.351 141.836 1.00 52.28  ? 44  SER F C   1 
ATOM   14064 O O   . SER F 1 25  ? 13.548  -15.477 141.534 1.00 49.75  ? 44  SER F O   1 
ATOM   14065 C CB  . SER F 1 25  ? 16.228  -15.868 139.892 1.00 63.83  ? 44  SER F CB  1 
ATOM   14066 O OG  . SER F 1 25  ? 16.804  -14.595 139.917 1.00 67.48  ? 44  SER F OG  1 
ATOM   14067 N N   . TRP F 1 26  ? 15.191  -14.391 142.634 1.00 59.78  ? 45  TRP F N   1 
ATOM   14068 C CA  . TRP F 1 26  ? 14.302  -13.340 143.111 1.00 55.94  ? 45  TRP F CA  1 
ATOM   14069 C C   . TRP F 1 26  ? 14.325  -12.078 142.241 1.00 60.36  ? 45  TRP F C   1 
ATOM   14070 O O   . TRP F 1 26  ? 13.638  -11.102 142.569 1.00 58.24  ? 45  TRP F O   1 
ATOM   14071 C CB  . TRP F 1 26  ? 14.672  -12.951 144.532 1.00 50.76  ? 45  TRP F CB  1 
ATOM   14072 C CG  . TRP F 1 26  ? 14.304  -13.916 145.616 1.00 46.56  ? 45  TRP F CG  1 
ATOM   14073 C CD1 . TRP F 1 26  ? 15.169  -14.593 146.447 1.00 45.97  ? 45  TRP F CD1 1 
ATOM   14074 C CD2 . TRP F 1 26  ? 12.974  -14.267 146.045 1.00 46.76  ? 45  TRP F CD2 1 
ATOM   14075 N NE1 . TRP F 1 26  ? 14.452  -15.343 147.354 1.00 45.80  ? 45  TRP F NE1 1 
ATOM   14076 C CE2 . TRP F 1 26  ? 13.107  -15.165 147.133 1.00 46.37  ? 45  TRP F CE2 1 
ATOM   14077 C CE3 . TRP F 1 26  ? 11.694  -13.911 145.620 1.00 47.97  ? 45  TRP F CE3 1 
ATOM   14078 C CZ2 . TRP F 1 26  ? 11.997  -15.715 147.799 1.00 46.82  ? 45  TRP F CZ2 1 
ATOM   14079 C CZ3 . TRP F 1 26  ? 10.592  -14.473 146.273 1.00 48.45  ? 45  TRP F CZ3 1 
ATOM   14080 C CH2 . TRP F 1 26  ? 10.757  -15.372 147.351 1.00 47.96  ? 45  TRP F CH2 1 
ATOM   14081 N N   . ASP F 1 27  ? 15.096  -12.058 141.152 1.00 50.87  ? 46  ASP F N   1 
ATOM   14082 C CA  . ASP F 1 27  ? 15.220  -10.835 140.371 1.00 56.43  ? 46  ASP F CA  1 
ATOM   14083 C C   . ASP F 1 27  ? 13.855  -10.234 140.101 1.00 54.39  ? 46  ASP F C   1 
ATOM   14084 O O   . ASP F 1 27  ? 13.624  -9.039  140.322 1.00 55.10  ? 46  ASP F O   1 
ATOM   14085 C CB  . ASP F 1 27  ? 15.956  -11.117 139.068 1.00 63.19  ? 46  ASP F CB  1 
ATOM   14086 C CG  . ASP F 1 27  ? 17.424  -11.421 139.290 1.00 65.64  ? 46  ASP F CG  1 
ATOM   14087 O OD1 . ASP F 1 27  ? 17.961  -11.140 140.391 1.00 64.02  ? 46  ASP F OD1 1 
ATOM   14088 O OD2 . ASP F 1 27  ? 18.058  -11.930 138.353 1.00 69.82  ? 46  ASP F OD2 1 
ATOM   14089 N N   . THR F 1 28  ? 12.921  -11.054 139.636 1.00 59.17  ? 47  THR F N   1 
ATOM   14090 C CA  . THR F 1 28  ? 11.569  -10.583 139.392 1.00 56.12  ? 47  THR F CA  1 
ATOM   14091 C C   . THR F 1 28  ? 10.613  -11.573 140.022 1.00 49.36  ? 47  THR F C   1 
ATOM   14092 O O   . THR F 1 28  ? 11.032  -12.527 140.682 1.00 47.56  ? 47  THR F O   1 
ATOM   14093 C CB  . THR F 1 28  ? 11.291  -10.401 137.897 1.00 59.58  ? 47  THR F CB  1 
ATOM   14094 O OG1 . THR F 1 28  ? 11.644  -11.599 137.205 1.00 61.41  ? 47  THR F OG1 1 
ATOM   14095 C CG2 . THR F 1 28  ? 12.091  -9.232  137.351 1.00 63.77  ? 47  THR F CG2 1 
ATOM   14096 N N   . VAL F 1 29  ? 9.321   -11.312 139.856 1.00 52.02  ? 48  VAL F N   1 
ATOM   14097 C CA  . VAL F 1 29  ? 8.271   -12.220 140.310 1.00 52.09  ? 48  VAL F CA  1 
ATOM   14098 C C   . VAL F 1 29  ? 8.535   -13.594 139.701 1.00 52.80  ? 48  VAL F C   1 
ATOM   14099 O O   . VAL F 1 29  ? 8.565   -13.720 138.473 1.00 54.97  ? 48  VAL F O   1 
ATOM   14100 C CB  . VAL F 1 29  ? 6.877   -11.686 139.935 1.00 54.25  ? 48  VAL F CB  1 
ATOM   14101 C CG1 . VAL F 1 29  ? 5.812   -12.738 140.186 1.00 55.26  ? 48  VAL F CG1 1 
ATOM   14102 C CG2 . VAL F 1 29  ? 6.563   -10.460 140.749 1.00 53.48  ? 48  VAL F CG2 1 
ATOM   14103 N N   . PRO F 1 30  ? 8.757   -14.631 140.507 1.00 52.84  ? 49  PRO F N   1 
ATOM   14104 C CA  . PRO F 1 30  ? 9.035   -15.979 139.951 1.00 53.76  ? 49  PRO F CA  1 
ATOM   14105 C C   . PRO F 1 30  ? 7.830   -16.604 139.267 1.00 56.34  ? 49  PRO F C   1 
ATOM   14106 O O   . PRO F 1 30  ? 6.786   -16.819 139.887 1.00 56.56  ? 49  PRO F O   1 
ATOM   14107 C CB  . PRO F 1 30  ? 9.466   -16.803 141.177 1.00 52.32  ? 49  PRO F CB  1 
ATOM   14108 C CG  . PRO F 1 30  ? 9.121   -16.011 142.365 1.00 51.52  ? 49  PRO F CG  1 
ATOM   14109 C CD  . PRO F 1 30  ? 9.035   -14.551 141.959 1.00 51.14  ? 49  PRO F CD  1 
ATOM   14110 N N   . ILE F 1 31  ? 8.006   -16.978 138.009 1.00 52.23  ? 50  ILE F N   1 
ATOM   14111 C CA  . ILE F 1 31  ? 6.905   -17.428 137.167 1.00 55.21  ? 50  ILE F CA  1 
ATOM   14112 C C   . ILE F 1 31  ? 7.134   -18.863 136.727 1.00 55.83  ? 50  ILE F C   1 
ATOM   14113 O O   . ILE F 1 31  ? 8.276   -19.279 136.490 1.00 55.69  ? 50  ILE F O   1 
ATOM   14114 C CB  . ILE F 1 31  ? 6.759   -16.519 135.933 1.00 57.95  ? 50  ILE F CB  1 
ATOM   14115 C CG1 . ILE F 1 31  ? 6.342   -15.119 136.360 1.00 57.62  ? 50  ILE F CG1 1 
ATOM   14116 C CG2 . ILE F 1 31  ? 5.736   -17.056 134.983 1.00 61.20  ? 50  ILE F CG2 1 
ATOM   14117 C CD1 . ILE F 1 31  ? 4.993   -15.094 137.059 1.00 57.93  ? 50  ILE F CD1 1 
ATOM   14118 N N   . ALA F 1 32  ? 6.032   -19.610 136.620 1.00 56.19  ? 51  ALA F N   1 
ATOM   14119 C CA  . ALA F 1 32  ? 5.981   -20.917 135.983 1.00 57.91  ? 51  ALA F CA  1 
ATOM   14120 C C   . ALA F 1 32  ? 4.823   -20.926 134.997 1.00 60.54  ? 51  ALA F C   1 
ATOM   14121 O O   . ALA F 1 32  ? 3.936   -20.059 135.034 1.00 61.14  ? 51  ALA F O   1 
ATOM   14122 C CB  . ALA F 1 32  ? 5.788   -22.063 136.986 1.00 56.81  ? 51  ALA F CB  1 
ATOM   14123 N N   . PHE F 1 33  ? 4.827   -21.942 134.126 1.00 61.86  ? 52  PHE F N   1 
ATOM   14124 C CA  . PHE F 1 33  ? 3.802   -22.110 133.105 1.00 64.55  ? 52  PHE F CA  1 
ATOM   14125 C C   . PHE F 1 33  ? 3.200   -23.505 133.217 1.00 65.32  ? 52  PHE F C   1 
ATOM   14126 O O   . PHE F 1 33  ? 3.907   -24.472 133.505 1.00 64.60  ? 52  PHE F O   1 
ATOM   14127 C CB  . PHE F 1 33  ? 4.368   -21.908 131.704 1.00 67.20  ? 52  PHE F CB  1 
ATOM   14128 C CG  . PHE F 1 33  ? 4.732   -20.488 131.382 1.00 67.24  ? 52  PHE F CG  1 
ATOM   14129 C CD1 . PHE F 1 33  ? 3.769   -19.572 130.965 1.00 68.66  ? 52  PHE F CD1 1 
ATOM   14130 C CD2 . PHE F 1 33  ? 6.055   -20.067 131.445 1.00 66.03  ? 52  PHE F CD2 1 
ATOM   14131 C CE1 . PHE F 1 33  ? 4.122   -18.258 130.650 1.00 69.15  ? 52  PHE F CE1 1 
ATOM   14132 C CE2 . PHE F 1 33  ? 6.411   -18.752 131.112 1.00 66.34  ? 52  PHE F CE2 1 
ATOM   14133 C CZ  . PHE F 1 33  ? 5.447   -17.854 130.728 1.00 67.97  ? 52  PHE F CZ  1 
ATOM   14134 N N   . HIS F 1 34  ? 1.902   -23.601 132.961 1.00 66.94  ? 53  HIS F N   1 
ATOM   14135 C CA  . HIS F 1 34  ? 1.179   -24.862 133.012 1.00 68.07  ? 53  HIS F CA  1 
ATOM   14136 C C   . HIS F 1 34  ? 0.040   -24.783 132.006 1.00 71.01  ? 53  HIS F C   1 
ATOM   14137 O O   . HIS F 1 34  ? -1.009  -24.223 132.328 1.00 71.58  ? 53  HIS F O   1 
ATOM   14138 C CB  . HIS F 1 34  ? 0.649   -25.101 134.408 1.00 66.30  ? 53  HIS F CB  1 
ATOM   14139 C CG  . HIS F 1 34  ? -0.009  -26.434 134.576 1.00 67.50  ? 53  HIS F CG  1 
ATOM   14140 N ND1 . HIS F 1 34  ? 0.452   -27.383 135.460 1.00 66.74  ? 53  HIS F ND1 1 
ATOM   14141 C CD2 . HIS F 1 34  ? -1.082  -26.984 133.960 1.00 70.28  ? 53  HIS F CD2 1 
ATOM   14142 C CE1 . HIS F 1 34  ? -0.322  -28.449 135.398 1.00 67.95  ? 53  HIS F CE1 1 
ATOM   14143 N NE2 . HIS F 1 34  ? -1.253  -28.238 134.489 1.00 70.12  ? 53  HIS F NE2 1 
ATOM   14144 N N   . PHE F 1 35  ? 0.247   -25.335 130.809 1.00 70.80  ? 54  PHE F N   1 
ATOM   14145 C CA  . PHE F 1 35  ? -0.761  -25.233 129.754 1.00 74.00  ? 54  PHE F CA  1 
ATOM   14146 C C   . PHE F 1 35  ? -0.434  -26.189 128.612 1.00 76.36  ? 54  PHE F C   1 
ATOM   14147 O O   . PHE F 1 35  ? 0.680   -26.711 128.514 1.00 75.74  ? 54  PHE F O   1 
ATOM   14148 C CB  . PHE F 1 35  ? -0.871  -23.797 129.211 1.00 74.80  ? 54  PHE F CB  1 
ATOM   14149 C CG  . PHE F 1 35  ? 0.329   -23.350 128.415 1.00 75.29  ? 54  PHE F CG  1 
ATOM   14150 C CD1 . PHE F 1 35  ? 0.475   -23.709 127.078 1.00 79.12  ? 54  PHE F CD1 1 
ATOM   14151 C CD2 . PHE F 1 35  ? 1.318   -22.577 129.003 1.00 72.88  ? 54  PHE F CD2 1 
ATOM   14152 C CE1 . PHE F 1 35  ? 1.585   -23.293 126.348 1.00 79.94  ? 54  PHE F CE1 1 
ATOM   14153 C CE2 . PHE F 1 35  ? 2.430   -22.161 128.277 1.00 73.57  ? 54  PHE F CE2 1 
ATOM   14154 C CZ  . PHE F 1 35  ? 2.568   -22.514 126.958 1.00 77.15  ? 54  PHE F CZ  1 
ATOM   14155 N N   . GLY F 1 36  ? -1.432  -26.387 127.723 1.00 78.29  ? 55  GLY F N   1 
ATOM   14156 C CA  . GLY F 1 36  ? -1.219  -27.104 126.491 1.00 81.00  ? 55  GLY F CA  1 
ATOM   14157 C C   . GLY F 1 36  ? -1.701  -26.328 125.273 1.00 83.99  ? 55  GLY F C   1 
ATOM   14158 O O   . GLY F 1 36  ? -2.560  -25.444 125.339 1.00 84.50  ? 55  GLY F O   1 
ATOM   14159 N N   . LYS F 1 37  ? -1.108  -26.684 124.136 1.00 86.05  ? 56  LYS F N   1 
ATOM   14160 C CA  . LYS F 1 37  ? -1.489  -26.192 122.811 1.00 89.35  ? 56  LYS F CA  1 
ATOM   14161 C C   . LYS F 1 37  ? -1.853  -27.424 121.984 1.00 91.93  ? 56  LYS F C   1 
ATOM   14162 O O   . LYS F 1 37  ? -0.991  -28.041 121.353 1.00 92.76  ? 56  LYS F O   1 
ATOM   14163 C CB  . LYS F 1 37  ? -0.358  -25.393 122.194 1.00 89.65  ? 56  LYS F CB  1 
ATOM   14164 C CG  . LYS F 1 37  ? -0.648  -24.842 120.810 1.00 93.23  ? 56  LYS F CG  1 
ATOM   14165 C CD  . LYS F 1 37  ? 0.618   -24.209 120.253 1.00 93.53  ? 56  LYS F CD  1 
ATOM   14166 C CE  . LYS F 1 37  ? 0.458   -23.744 118.822 1.00 97.35  ? 56  LYS F CE  1 
ATOM   14167 N NZ  . LYS F 1 37  ? 1.717   -23.132 118.302 1.00 97.74  ? 56  LYS F NZ  1 
ATOM   14168 N N   A SER F 1 38  ? -3.136  -27.783 121.986 0.18 93.27  ? 57  SER F N   1 
ATOM   14169 N N   B SER F 1 38  ? -3.143  -27.779 122.015 0.82 93.24  ? 57  SER F N   1 
ATOM   14170 C CA  A SER F 1 38  ? -3.551  -29.014 121.322 0.18 95.57  ? 57  SER F CA  1 
ATOM   14171 C CA  B SER F 1 38  ? -3.622  -28.967 121.308 0.82 95.64  ? 57  SER F CA  1 
ATOM   14172 C C   A SER F 1 38  ? -3.205  -29.009 119.837 0.18 98.80  ? 57  SER F C   1 
ATOM   14173 C C   B SER F 1 38  ? -3.157  -28.988 119.858 0.82 98.73  ? 57  SER F C   1 
ATOM   14174 O O   A SER F 1 38  ? -2.896  -30.064 119.272 0.18 100.15 ? 57  SER F O   1 
ATOM   14175 O O   B SER F 1 38  ? -2.711  -30.020 119.345 0.82 99.92  ? 57  SER F O   1 
ATOM   14176 C CB  A SER F 1 38  ? -5.054  -29.222 121.517 0.18 96.68  ? 57  SER F CB  1 
ATOM   14177 C CB  B SER F 1 38  ? -5.153  -29.020 121.354 0.82 97.01  ? 57  SER F CB  1 
ATOM   14178 O OG  A SER F 1 38  ? -5.785  -28.106 121.039 0.18 98.43  ? 57  SER F OG  1 
ATOM   14179 O OG  B SER F 1 38  ? -5.662  -28.673 122.625 0.82 94.39  ? 57  SER F OG  1 
ATOM   14180 N N   . GLN F 1 39  ? -3.252  -27.844 119.189 1.00 100.17 ? 58  GLN F N   1 
ATOM   14181 C CA  . GLN F 1 39  ? -3.085  -27.767 117.748 1.00 103.66 ? 58  GLN F CA  1 
ATOM   14182 C C   . GLN F 1 39  ? -1.654  -27.918 117.256 1.00 103.71 ? 58  GLN F C   1 
ATOM   14183 O O   . GLN F 1 39  ? -1.459  -28.090 116.049 1.00 106.71 ? 58  GLN F O   1 
ATOM   14184 C CB  . GLN F 1 39  ? -3.642  -26.421 117.256 1.00 105.21 ? 58  GLN F CB  1 
ATOM   14185 C CG  . GLN F 1 39  ? -4.858  -25.917 118.037 1.00 104.40 ? 58  GLN F CG  1 
ATOM   14186 C CD  . GLN F 1 39  ? -4.498  -24.887 119.087 1.00 101.35 ? 58  GLN F CD  1 
ATOM   14187 O OE1 . GLN F 1 39  ? -3.620  -24.061 118.869 1.00 101.14 ? 58  GLN F OE1 1 
ATOM   14188 N NE2 . GLN F 1 39  ? -5.181  -24.924 120.224 1.00 99.17  ? 58  GLN F NE2 1 
ATOM   14189 N N   . GLY F 1 40  ? -0.655  -27.840 118.116 1.00 100.67 ? 59  GLY F N   1 
ATOM   14190 C CA  . GLY F 1 40  ? 0.699   -27.986 117.624 1.00 100.84 ? 59  GLY F CA  1 
ATOM   14191 C C   . GLY F 1 40  ? 1.729   -27.536 118.639 1.00 97.36  ? 59  GLY F C   1 
ATOM   14192 O O   . GLY F 1 40  ? 1.409   -27.079 119.744 1.00 94.72  ? 59  GLY F O   1 
ATOM   14193 N N   . LEU F 1 41  ? 2.986   -27.697 118.235 1.00 97.47  ? 60  LEU F N   1 
ATOM   14194 C CA  . LEU F 1 41  ? 4.081   -27.156 119.008 1.00 94.50  ? 60  LEU F CA  1 
ATOM   14195 C C   . LEU F 1 41  ? 4.007   -25.631 119.038 1.00 94.16  ? 60  LEU F C   1 
ATOM   14196 O O   . LEU F 1 41  ? 3.452   -24.978 118.142 1.00 96.84  ? 60  LEU F O   1 
ATOM   14197 C CB  . LEU F 1 41  ? 5.427   -27.550 118.414 1.00 95.80  ? 60  LEU F CB  1 
ATOM   14198 C CG  . LEU F 1 41  ? 5.934   -28.979 118.454 1.00 96.27  ? 60  LEU F CG  1 
ATOM   14199 C CD1 . LEU F 1 41  ? 7.266   -29.034 117.722 1.00 98.59  ? 60  LEU F CD1 1 
ATOM   14200 C CD2 . LEU F 1 41  ? 6.076   -29.441 119.879 1.00 92.53  ? 60  LEU F CD2 1 
ATOM   14201 N N   . LEU F 1 42  ? 4.604   -25.064 120.079 1.00 90.95  ? 61  LEU F N   1 
ATOM   14202 C CA  . LEU F 1 42  ? 4.754   -23.622 120.163 1.00 90.78  ? 61  LEU F CA  1 
ATOM   14203 C C   . LEU F 1 42  ? 5.517   -23.107 118.949 1.00 94.49  ? 61  LEU F C   1 
ATOM   14204 O O   . LEU F 1 42  ? 6.504   -23.712 118.516 1.00 96.06  ? 61  LEU F O   1 
ATOM   14205 C CB  . LEU F 1 42  ? 5.486   -23.255 121.450 1.00 87.44  ? 61  LEU F CB  1 
ATOM   14206 C CG  . LEU F 1 42  ? 4.778   -23.659 122.743 1.00 83.76  ? 61  LEU F CG  1 
ATOM   14207 C CD1 . LEU F 1 42  ? 5.615   -23.254 123.951 1.00 80.67  ? 61  LEU F CD1 1 
ATOM   14208 C CD2 . LEU F 1 42  ? 3.398   -23.032 122.847 1.00 84.50  ? 61  LEU F CD2 1 
ATOM   14209 N N   . THR F 1 43  ? 5.050   -21.984 118.394 1.00 96.04  ? 62  THR F N   1 
ATOM   14210 C CA  . THR F 1 43  ? 5.763   -21.362 117.295 1.00 99.48  ? 62  THR F CA  1 
ATOM   14211 C C   . THR F 1 43  ? 7.156   -20.929 117.762 1.00 98.45  ? 62  THR F C   1 
ATOM   14212 O O   . THR F 1 43  ? 7.478   -20.955 118.950 1.00 95.01  ? 62  THR F O   1 
ATOM   14213 C CB  . THR F 1 43  ? 5.004   -20.150 116.754 1.00 101.21 ? 62  THR F CB  1 
ATOM   14214 O OG1 . THR F 1 43  ? 5.400   -18.987 117.488 1.00 98.97  ? 62  THR F OG1 1 
ATOM   14215 C CG2 . THR F 1 43  ? 3.487   -20.315 116.857 1.00 100.58 ? 62  THR F CG2 1 
ATOM   14216 N N   . LYS F 1 44  ? 7.989   -20.522 116.801 1.00 101.56 ? 63  LYS F N   1 
ATOM   14217 C CA  . LYS F 1 44  ? 9.269   -19.909 117.145 1.00 100.93 ? 63  LYS F CA  1 
ATOM   14218 C C   . LYS F 1 44  ? 9.087   -18.835 118.216 1.00 98.13  ? 63  LYS F C   1 
ATOM   14219 O O   . LYS F 1 44  ? 9.718   -18.887 119.280 1.00 95.30  ? 63  LYS F O   1 
ATOM   14220 C CB  . LYS F 1 44  ? 9.919   -19.319 115.890 1.00 105.08 ? 63  LYS F CB  1 
ATOM   14221 N N   . GLU F 1 45  ? 8.204   -17.858 117.958 1.00 98.86  ? 64  GLU F N   1 
ATOM   14222 C CA  . GLU F 1 45  ? 8.024   -16.744 118.891 1.00 96.54  ? 64  GLU F CA  1 
ATOM   14223 C C   . GLU F 1 45  ? 7.418   -17.191 120.221 1.00 92.21  ? 64  GLU F C   1 
ATOM   14224 O O   . GLU F 1 45  ? 7.732   -16.604 121.265 1.00 89.41  ? 64  GLU F O   1 
ATOM   14225 C CB  . GLU F 1 45  ? 7.143   -15.660 118.259 1.00 98.64  ? 64  GLU F CB  1 
ATOM   14226 N N   . GLU F 1 46  ? 6.556   -18.209 120.207 1.00 91.73  ? 65  GLU F N   1 
ATOM   14227 C CA  . GLU F 1 46  ? 5.891   -18.635 121.430 1.00 87.94  ? 65  GLU F CA  1 
ATOM   14228 C C   . GLU F 1 46  ? 6.801   -19.469 122.321 1.00 85.53  ? 65  GLU F C   1 
ATOM   14229 O O   . GLU F 1 46  ? 6.692   -19.382 123.554 1.00 82.07  ? 65  GLU F O   1 
ATOM   14230 C CB  . GLU F 1 46  ? 4.627   -19.430 121.091 1.00 88.54  ? 65  GLU F CB  1 
ATOM   14231 C CG  . GLU F 1 46  ? 3.513   -18.563 120.518 1.00 90.48  ? 65  GLU F CG  1 
ATOM   14232 C CD  . GLU F 1 46  ? 2.470   -19.372 119.803 1.00 93.23  ? 65  GLU F CD  1 
ATOM   14233 O OE1 . GLU F 1 46  ? 2.609   -20.610 119.712 1.00 93.16  ? 65  GLU F OE1 1 
ATOM   14234 O OE2 . GLU F 1 46  ? 1.466   -18.790 119.370 1.00 95.62  ? 65  GLU F OE2 1 
ATOM   14235 N N   . ALA F 1 47  ? 7.698   -20.261 121.726 1.00 87.35  ? 66  ALA F N   1 
ATOM   14236 C CA  . ALA F 1 47  ? 8.692   -20.965 122.530 1.00 85.36  ? 66  ALA F CA  1 
ATOM   14237 C C   . ALA F 1 47  ? 9.789   -20.022 123.019 1.00 84.20  ? 66  ALA F C   1 
ATOM   14238 O O   . ALA F 1 47  ? 10.387  -20.274 124.076 1.00 81.18  ? 66  ALA F O   1 
ATOM   14239 C CB  . ALA F 1 47  ? 9.306   -22.115 121.733 1.00 87.88  ? 66  ALA F CB  1 
ATOM   14240 N N   . GLU F 1 48  ? 10.082  -18.960 122.259 1.00 86.82  ? 67  GLU F N   1 
ATOM   14241 C CA  . GLU F 1 48  ? 10.978  -17.918 122.752 1.00 86.07  ? 67  GLU F CA  1 
ATOM   14242 C C   . GLU F 1 48  ? 10.377  -17.246 123.982 1.00 82.64  ? 67  GLU F C   1 
ATOM   14243 O O   . GLU F 1 48  ? 11.050  -17.057 124.999 1.00 80.22  ? 67  GLU F O   1 
ATOM   14244 C CB  . GLU F 1 48  ? 11.258  -16.881 121.655 1.00 89.76  ? 67  GLU F CB  1 
ATOM   14245 N N   . PHE F 1 49  ? 9.087   -16.903 123.911 1.00 82.39  ? 68  PHE F N   1 
ATOM   14246 C CA  . PHE F 1 49  ? 8.435   -16.191 125.003 1.00 79.29  ? 68  PHE F CA  1 
ATOM   14247 C C   . PHE F 1 49  ? 8.530   -16.969 126.312 1.00 75.51  ? 68  PHE F C   1 
ATOM   14248 O O   . PHE F 1 49  ? 8.906   -16.419 127.356 1.00 72.94  ? 68  PHE F O   1 
ATOM   14249 C CB  . PHE F 1 49  ? 6.981   -15.923 124.625 1.00 79.98  ? 68  PHE F CB  1 
ATOM   14250 C CG  . PHE F 1 49  ? 6.196   -15.231 125.687 1.00 77.06  ? 68  PHE F CG  1 
ATOM   14251 C CD1 . PHE F 1 49  ? 5.567   -15.952 126.690 1.00 73.88  ? 68  PHE F CD1 1 
ATOM   14252 C CD2 . PHE F 1 49  ? 6.097   -13.856 125.702 1.00 77.50  ? 68  PHE F CD2 1 
ATOM   14253 C CE1 . PHE F 1 49  ? 4.851   -15.296 127.683 1.00 71.22  ? 68  PHE F CE1 1 
ATOM   14254 C CE2 . PHE F 1 49  ? 5.380   -13.204 126.679 1.00 74.85  ? 68  PHE F CE2 1 
ATOM   14255 C CZ  . PHE F 1 49  ? 4.751   -13.913 127.660 1.00 71.72  ? 68  PHE F CZ  1 
ATOM   14256 N N   . VAL F 1 50  ? 8.211   -18.262 126.266 1.00 77.03  ? 69  VAL F N   1 
ATOM   14257 C CA  . VAL F 1 50  ? 8.213   -19.098 127.466 1.00 74.09  ? 69  VAL F CA  1 
ATOM   14258 C C   . VAL F 1 50  ? 9.631   -19.318 127.971 1.00 73.17  ? 69  VAL F C   1 
ATOM   14259 O O   . VAL F 1 50  ? 9.889   -19.235 129.175 1.00 70.14  ? 69  VAL F O   1 
ATOM   14260 C CB  . VAL F 1 50  ? 7.513   -20.442 127.169 1.00 75.59  ? 69  VAL F CB  1 
ATOM   14261 C CG1 . VAL F 1 50  ? 7.872   -21.485 128.220 1.00 73.84  ? 69  VAL F CG1 1 
ATOM   14262 C CG2 . VAL F 1 50  ? 6.008   -20.258 127.092 1.00 75.54  ? 69  VAL F CG2 1 
ATOM   14263 N N   . ALA F 1 51  ? 10.565  -19.636 127.073 1.00 74.03  ? 70  ALA F N   1 
ATOM   14264 C CA  . ALA F 1 51  ? 11.893  -20.051 127.520 1.00 73.50  ? 70  ALA F CA  1 
ATOM   14265 C C   . ALA F 1 51  ? 12.665  -18.897 128.151 1.00 72.80  ? 70  ALA F C   1 
ATOM   14266 O O   . ALA F 1 51  ? 13.537  -19.122 128.998 1.00 73.74  ? 70  ALA F O   1 
ATOM   14267 C CB  . ALA F 1 51  ? 12.696  -20.624 126.354 1.00 76.99  ? 70  ALA F CB  1 
ATOM   14268 N N   . THR F 1 52  ? 12.377  -17.658 127.741 1.00 73.38  ? 71  THR F N   1 
ATOM   14269 C CA  . THR F 1 52  ? 13.108  -16.512 128.259 1.00 72.80  ? 71  THR F CA  1 
ATOM   14270 C C   . THR F 1 52  ? 12.572  -16.022 129.593 1.00 68.97  ? 71  THR F C   1 
ATOM   14271 O O   . THR F 1 52  ? 13.219  -15.183 130.232 1.00 68.16  ? 71  THR F O   1 
ATOM   14272 C CB  . THR F 1 52  ? 13.063  -15.345 127.268 1.00 76.01  ? 71  THR F CB  1 
ATOM   14273 O OG1 . THR F 1 52  ? 11.703  -15.057 126.919 1.00 77.56  ? 71  THR F OG1 1 
ATOM   14274 C CG2 . THR F 1 52  ? 13.836  -15.654 126.003 1.00 74.93  ? 71  THR F CG2 1 
ATOM   14275 N N   . ARG F 1 53  ? 11.421  -16.510 130.033 1.00 68.88  ? 72  ARG F N   1 
ATOM   14276 C CA  . ARG F 1 53  ? 10.736  -15.926 131.178 1.00 65.34  ? 72  ARG F CA  1 
ATOM   14277 C C   . ARG F 1 53  ? 10.537  -16.894 132.330 1.00 62.11  ? 72  ARG F C   1 
ATOM   14278 O O   . ARG F 1 53  ? 9.999   -16.487 133.365 1.00 59.26  ? 72  ARG F O   1 
ATOM   14279 C CB  . ARG F 1 53  ? 9.387   -15.342 130.724 1.00 65.96  ? 72  ARG F CB  1 
ATOM   14280 C CG  . ARG F 1 53  ? 9.624   -14.276 129.671 1.00 69.01  ? 72  ARG F CG  1 
ATOM   14281 C CD  . ARG F 1 53  ? 8.374   -13.625 129.091 1.00 70.25  ? 72  ARG F CD  1 
ATOM   14282 N NE  . ARG F 1 53  ? 8.724   -12.902 127.871 1.00 73.89  ? 72  ARG F NE  1 
ATOM   14283 C CZ  . ARG F 1 53  ? 8.306   -11.676 127.590 1.00 75.34  ? 72  ARG F CZ  1 
ATOM   14284 N NH1 . ARG F 1 53  ? 7.429   -11.051 128.365 1.00 73.60  ? 72  ARG F NH1 1 
ATOM   14285 N NH2 . ARG F 1 53  ? 8.779   -11.057 126.508 1.00 79.26  ? 72  ARG F NH2 1 
ATOM   14286 N N   . SER F 1 54  ? 10.980  -18.147 132.198 1.00 65.67  ? 73  SER F N   1 
ATOM   14287 C CA  . SER F 1 54  ? 10.770  -19.156 133.227 1.00 62.61  ? 73  SER F CA  1 
ATOM   14288 C C   . SER F 1 54  ? 11.735  -20.320 133.036 1.00 65.13  ? 73  SER F C   1 
ATOM   14289 O O   . SER F 1 54  ? 12.197  -20.595 131.921 1.00 69.39  ? 73  SER F O   1 
ATOM   14290 C CB  . SER F 1 54  ? 9.324   -19.672 133.217 1.00 62.01  ? 73  SER F CB  1 
ATOM   14291 O OG  . SER F 1 54  ? 9.118   -20.637 134.230 1.00 59.69  ? 73  SER F OG  1 
ATOM   14292 N N   . ASN F 1 55  ? 12.041  -20.987 134.160 1.00 63.65  ? 74  ASN F N   1 
ATOM   14293 C CA  . ASN F 1 55  ? 12.795  -22.234 134.175 1.00 64.67  ? 74  ASN F CA  1 
ATOM   14294 C C   . ASN F 1 55  ? 11.910  -23.453 134.508 1.00 60.88  ? 74  ASN F C   1 
ATOM   14295 O O   . ASN F 1 55  ? 12.437  -24.508 134.842 1.00 61.36  ? 74  ASN F O   1 
ATOM   14296 C CB  . ASN F 1 55  ? 13.944  -22.182 135.190 1.00 65.39  ? 74  ASN F CB  1 
ATOM   14297 C CG  . ASN F 1 55  ? 15.063  -21.233 134.810 1.00 70.14  ? 74  ASN F CG  1 
ATOM   14298 O OD1 . ASN F 1 55  ? 15.346  -21.025 133.642 1.00 74.53  ? 74  ASN F OD1 1 
ATOM   14299 N ND2 . ASN F 1 55  ? 15.738  -20.677 135.827 1.00 70.25  ? 74  ASN F ND2 1 
ATOM   14300 N N   . PHE F 1 56  ? 10.580  -23.339 134.435 1.00 61.83  ? 75  PHE F N   1 
ATOM   14301 C CA  . PHE F 1 56  ? 9.684   -24.330 135.046 1.00 60.04  ? 75  PHE F CA  1 
ATOM   14302 C C   . PHE F 1 56  ? 8.368   -24.365 134.280 1.00 62.20  ? 75  PHE F C   1 
ATOM   14303 O O   . PHE F 1 56  ? 7.605   -23.395 134.312 1.00 62.53  ? 75  PHE F O   1 
ATOM   14304 C CB  . PHE F 1 56  ? 9.446   -23.960 136.507 1.00 57.49  ? 75  PHE F CB  1 
ATOM   14305 C CG  . PHE F 1 56  ? 8.862   -25.054 137.363 1.00 57.00  ? 75  PHE F CG  1 
ATOM   14306 C CD1 . PHE F 1 56  ? 8.831   -26.372 136.939 1.00 58.59  ? 75  PHE F CD1 1 
ATOM   14307 C CD2 . PHE F 1 56  ? 8.359   -24.744 138.634 1.00 55.36  ? 75  PHE F CD2 1 
ATOM   14308 C CE1 . PHE F 1 56  ? 8.293   -27.355 137.756 1.00 58.35  ? 75  PHE F CE1 1 
ATOM   14309 C CE2 . PHE F 1 56  ? 7.834   -25.721 139.457 1.00 55.13  ? 75  PHE F CE2 1 
ATOM   14310 C CZ  . PHE F 1 56  ? 7.798   -27.038 139.017 1.00 56.62  ? 75  PHE F CZ  1 
ATOM   14311 N N   . ILE F 1 57  ? 8.070   -25.484 133.628 1.00 62.92  ? 76  ILE F N   1 
ATOM   14312 C CA  . ILE F 1 57  ? 6.829   -25.556 132.868 1.00 65.13  ? 76  ILE F CA  1 
ATOM   14313 C C   . ILE F 1 57  ? 6.308   -26.988 132.836 1.00 66.23  ? 76  ILE F C   1 
ATOM   14314 O O   . ILE F 1 57  ? 7.055   -27.940 132.591 1.00 67.05  ? 76  ILE F O   1 
ATOM   14315 C CB  . ILE F 1 57  ? 7.015   -25.017 131.432 1.00 67.73  ? 76  ILE F CB  1 
ATOM   14316 C CG1 . ILE F 1 57  ? 5.695   -25.137 130.668 1.00 70.38  ? 76  ILE F CG1 1 
ATOM   14317 C CG2 . ILE F 1 57  ? 8.124   -25.781 130.743 1.00 69.09  ? 76  ILE F CG2 1 
ATOM   14318 C CD1 . ILE F 1 57  ? 5.611   -24.258 129.423 1.00 73.03  ? 76  ILE F CD1 1 
ATOM   14319 N N   . CYS F 1 58  ? 5.002   -27.121 133.046 1.00 66.21  ? 77  CYS F N   1 
ATOM   14320 C CA  . CYS F 1 58  ? 4.285   -28.354 132.807 1.00 67.74  ? 77  CYS F CA  1 
ATOM   14321 C C   . CYS F 1 58  ? 3.442   -28.243 131.540 1.00 71.13  ? 77  CYS F C   1 
ATOM   14322 O O   . CYS F 1 58  ? 2.546   -27.393 131.447 1.00 71.58  ? 77  CYS F O   1 
ATOM   14323 C CB  . CYS F 1 58  ? 3.375   -28.715 133.967 1.00 66.50  ? 77  CYS F CB  1 
ATOM   14324 S SG  . CYS F 1 58  ? 2.564   -30.317 133.538 1.00 69.02  ? 77  CYS F SG  1 
ATOM   14325 N N   . LEU F 1 59  ? 3.693   -29.131 130.590 1.00 70.29  ? 78  LEU F N   1 
ATOM   14326 C CA  . LEU F 1 59  ? 2.878   -29.223 129.386 1.00 73.26  ? 78  LEU F CA  1 
ATOM   14327 C C   . LEU F 1 59  ? 1.705   -30.157 129.655 1.00 74.12  ? 78  LEU F C   1 
ATOM   14328 O O   . LEU F 1 59  ? 1.889   -31.277 130.141 1.00 73.91  ? 78  LEU F O   1 
ATOM   14329 C CB  . LEU F 1 59  ? 3.733   -29.696 128.209 1.00 75.37  ? 78  LEU F CB  1 
ATOM   14330 C CG  . LEU F 1 59  ? 4.834   -28.685 127.856 1.00 75.01  ? 78  LEU F CG  1 
ATOM   14331 C CD1 . LEU F 1 59  ? 5.947   -29.244 126.994 1.00 76.28  ? 78  LEU F CD1 1 
ATOM   14332 C CD2 . LEU F 1 59  ? 4.209   -27.457 127.169 1.00 76.56  ? 78  LEU F CD2 1 
ATOM   14333 N N   . GLU F 1 60  ? 0.496   -29.678 129.354 1.00 74.59  ? 79  GLU F N   1 
ATOM   14334 C CA  . GLU F 1 60  ? -0.729  -30.374 129.716 1.00 75.43  ? 79  GLU F CA  1 
ATOM   14335 C C   . GLU F 1 60  ? -1.057  -31.457 128.692 1.00 78.34  ? 79  GLU F C   1 
ATOM   14336 O O   . GLU F 1 60  ? -0.376  -31.618 127.670 1.00 79.94  ? 79  GLU F O   1 
ATOM   14337 C CB  . GLU F 1 60  ? -1.896  -29.394 129.809 1.00 75.88  ? 79  GLU F CB  1 
ATOM   14338 C CG  . GLU F 1 60  ? -2.182  -28.844 131.187 1.00 73.24  ? 79  GLU F CG  1 
ATOM   14339 C CD  . GLU F 1 60  ? -3.082  -29.744 132.001 1.00 73.00  ? 79  GLU F CD  1 
ATOM   14340 O OE1 . GLU F 1 60  ? -3.719  -30.665 131.408 1.00 75.15  ? 79  GLU F OE1 1 
ATOM   14341 O OE2 . GLU F 1 60  ? -3.126  -29.529 133.250 1.00 70.81  ? 79  GLU F OE2 1 
ATOM   14342 N N   . LYS F 1 61  ? -2.123  -32.204 128.997 1.00 78.95  ? 80  LYS F N   1 
ATOM   14343 C CA  . LYS F 1 61  ? -2.669  -33.212 128.088 1.00 81.91  ? 80  LYS F CA  1 
ATOM   14344 C C   . LYS F 1 61  ? -3.179  -32.580 126.791 1.00 84.66  ? 80  LYS F C   1 
ATOM   14345 O O   . LYS F 1 61  ? -3.790  -31.503 126.784 1.00 84.64  ? 80  LYS F O   1 
ATOM   14346 C CB  . LYS F 1 61  ? -3.820  -33.951 128.777 1.00 81.90  ? 80  LYS F CB  1 
ATOM   14347 C CG  . LYS F 1 61  ? -4.943  -32.980 129.115 1.00 81.83  ? 80  LYS F CG  1 
ATOM   14348 C CD  . LYS F 1 61  ? -6.007  -33.529 130.042 1.00 81.69  ? 80  LYS F CD  1 
ATOM   14349 C CE  . LYS F 1 61  ? -6.593  -32.354 130.854 1.00 80.24  ? 80  LYS F CE  1 
ATOM   14350 N NZ  . LYS F 1 61  ? -6.068  -32.253 132.250 1.00 77.11  ? 80  LYS F NZ  1 
ATOM   14351 N N   . GLY F 1 62  ? -2.946  -33.283 125.689 1.00 87.19  ? 81  GLY F N   1 
ATOM   14352 C CA  . GLY F 1 62  ? -3.375  -32.855 124.384 1.00 90.16  ? 81  GLY F CA  1 
ATOM   14353 C C   . GLY F 1 62  ? -2.314  -32.117 123.615 1.00 90.45  ? 81  GLY F C   1 
ATOM   14354 O O   . GLY F 1 62  ? -2.495  -31.870 122.420 1.00 93.17  ? 81  GLY F O   1 
ATOM   14355 N N   . HIS F 1 63  ? -1.200  -31.805 124.254 1.00 87.88  ? 82  HIS F N   1 
ATOM   14356 C CA  . HIS F 1 63  ? -0.267  -30.855 123.685 1.00 87.97  ? 82  HIS F CA  1 
ATOM   14357 C C   . HIS F 1 63  ? 0.233   -31.339 122.344 1.00 90.74  ? 82  HIS F C   1 
ATOM   14358 O O   . HIS F 1 63  ? 0.831   -32.415 122.246 1.00 90.97  ? 82  HIS F O   1 
ATOM   14359 C CB  . HIS F 1 63  ? 0.925   -30.628 124.611 1.00 84.78  ? 82  HIS F CB  1 
ATOM   14360 C CG  . HIS F 1 63  ? 1.929   -29.669 124.059 1.00 84.71  ? 82  HIS F CG  1 
ATOM   14361 N ND1 . HIS F 1 63  ? 1.677   -28.323 123.966 1.00 84.58  ? 82  HIS F ND1 1 
ATOM   14362 C CD2 . HIS F 1 63  ? 3.163   -29.863 123.536 1.00 84.96  ? 82  HIS F CD2 1 
ATOM   14363 C CE1 . HIS F 1 63  ? 2.727   -27.719 123.437 1.00 84.70  ? 82  HIS F CE1 1 
ATOM   14364 N NE2 . HIS F 1 63  ? 3.645   -28.630 123.173 1.00 84.90  ? 82  HIS F NE2 1 
ATOM   14365 N N   . ALA F 1 64  ? 0.018   -30.510 121.322 1.00 92.87  ? 83  ALA F N   1 
ATOM   14366 C CA  . ALA F 1 64  ? 0.517   -30.757 119.975 1.00 95.74  ? 83  ALA F CA  1 
ATOM   14367 C C   . ALA F 1 64  ? -0.057  -32.041 119.362 1.00 98.23  ? 83  ALA F C   1 
ATOM   14368 O O   . ALA F 1 64  ? 0.550   -32.617 118.459 1.00 100.21 ? 83  ALA F O   1 
ATOM   14369 C CB  . ALA F 1 64  ? 2.055   -30.786 119.985 1.00 94.56  ? 83  ALA F CB  1 
ATOM   14370 N N   . THR F 1 65  ? -1.234  -32.493 119.816 1.00 98.16  ? 84  THR F N   1 
ATOM   14371 C CA  . THR F 1 65  ? -1.794  -33.743 119.301 1.00 100.50 ? 84  THR F CA  1 
ATOM   14372 C C   . THR F 1 65  ? -2.318  -33.600 117.868 1.00 104.32 ? 84  THR F C   1 
ATOM   14373 O O   . THR F 1 65  ? -2.333  -34.579 117.119 1.00 106.59 ? 84  THR F O   1 
ATOM   14374 C CB  . THR F 1 65  ? -2.923  -34.234 120.212 1.00 99.62  ? 84  THR F CB  1 
ATOM   14375 O OG1 . THR F 1 65  ? -3.752  -33.124 120.587 1.00 99.18  ? 84  THR F OG1 1 
ATOM   14376 C CG2 . THR F 1 65  ? -2.371  -34.885 121.477 1.00 96.54  ? 84  THR F CG2 1 
ATOM   14377 N N   . ARG F 1 66  ? -2.754  -32.407 117.460 1.00 105.21 ? 85  ARG F N   1 
ATOM   14378 C CA  . ARG F 1 66  ? -3.246  -32.243 116.098 1.00 109.01 ? 85  ARG F CA  1 
ATOM   14379 C C   . ARG F 1 66  ? -2.173  -32.526 115.056 1.00 110.74 ? 85  ARG F C   1 
ATOM   14380 O O   . ARG F 1 66  ? -2.513  -32.839 113.913 1.00 113.91 ? 85  ARG F O   1 
ATOM   14381 C CB  . ARG F 1 66  ? -3.794  -30.827 115.893 1.00 109.68 ? 85  ARG F CB  1 
ATOM   14382 N N   . THR F 1 67  ? -0.898  -32.447 115.419 1.00 108.84 ? 86  THR F N   1 
ATOM   14383 C CA  . THR F 1 67  ? 0.188   -32.682 114.483 1.00 110.36 ? 86  THR F CA  1 
ATOM   14384 C C   . THR F 1 67  ? 1.126   -33.810 114.882 1.00 109.13 ? 86  THR F C   1 
ATOM   14385 O O   . THR F 1 67  ? 1.885   -34.284 114.031 1.00 111.10 ? 86  THR F O   1 
ATOM   14386 C CB  . THR F 1 67  ? 1.045   -31.415 114.306 1.00 109.59 ? 86  THR F CB  1 
ATOM   14387 O OG1 . THR F 1 67  ? 2.284   -31.765 113.669 1.00 110.61 ? 86  THR F OG1 1 
ATOM   14388 C CG2 . THR F 1 67  ? 1.346   -30.770 115.658 1.00 105.56 ? 86  THR F CG2 1 
ATOM   14389 N N   . HIS F 1 68  ? 1.127   -34.228 116.136 1.00 105.96 ? 87  HIS F N   1 
ATOM   14390 C CA  . HIS F 1 68  ? 2.008   -35.281 116.597 1.00 104.74 ? 87  HIS F CA  1 
ATOM   14391 C C   . HIS F 1 68  ? 1.249   -36.507 117.072 1.00 104.79 ? 87  HIS F C   1 
ATOM   14392 O O   . HIS F 1 68  ? 1.878   -37.526 117.378 1.00 104.22 ? 87  HIS F O   1 
ATOM   14393 C CB  . HIS F 1 68  ? 2.913   -34.765 117.731 1.00 101.12 ? 87  HIS F CB  1 
ATOM   14394 C CG  . HIS F 1 68  ? 3.992   -33.831 117.260 1.00 101.11 ? 87  HIS F CG  1 
ATOM   14395 N ND1 . HIS F 1 68  ? 3.727   -32.586 116.724 1.00 102.28 ? 87  HIS F ND1 1 
ATOM   14396 C CD2 . HIS F 1 68  ? 5.339   -33.960 117.255 1.00 100.33 ? 87  HIS F CD2 1 
ATOM   14397 C CE1 . HIS F 1 68  ? 4.863   -31.992 116.409 1.00 102.15 ? 87  HIS F CE1 1 
ATOM   14398 N NE2 . HIS F 1 68  ? 5.857   -32.801 116.726 1.00 101.47 ? 87  HIS F NE2 1 
ATOM   14399 N N   . GLY F 1 69  ? -0.066  -36.445 117.137 1.00 105.66 ? 88  GLY F N   1 
ATOM   14400 C CA  . GLY F 1 69  ? -0.838  -37.624 117.405 1.00 106.36 ? 88  GLY F CA  1 
ATOM   14401 C C   . GLY F 1 69  ? -1.053  -37.860 118.874 1.00 103.27 ? 88  GLY F C   1 
ATOM   14402 O O   . GLY F 1 69  ? -2.192  -37.794 119.344 1.00 103.24 ? 88  GLY F O   1 
ATOM   14403 N N   . THR F 1 70  ? 0.025   -38.136 119.609 1.00 100.75 ? 89  THR F N   1 
ATOM   14404 C CA  . THR F 1 70  ? -0.043  -38.488 121.021 1.00 97.92  ? 89  THR F CA  1 
ATOM   14405 C C   . THR F 1 70  ? 0.474   -37.351 121.893 1.00 94.77  ? 89  THR F C   1 
ATOM   14406 O O   . THR F 1 70  ? 1.341   -36.576 121.481 1.00 94.49  ? 89  THR F O   1 
ATOM   14407 C CB  . THR F 1 70  ? 0.788   -39.746 121.325 1.00 97.49  ? 89  THR F CB  1 
ATOM   14408 O OG1 . THR F 1 70  ? 2.181   -39.446 121.154 1.00 96.71  ? 89  THR F OG1 1 
ATOM   14409 C CG2 . THR F 1 70  ? 0.420   -40.882 120.409 1.00 100.64 ? 89  THR F CG2 1 
ATOM   14410 N N   . THR F 1 71  ? -0.037  -37.262 123.121 1.00 92.42  ? 90  THR F N   1 
ATOM   14411 C CA  . THR F 1 71  ? 0.542   -36.289 124.042 1.00 89.33  ? 90  THR F CA  1 
ATOM   14412 C C   . THR F 1 71  ? 1.995   -36.643 124.351 1.00 87.90  ? 90  THR F C   1 
ATOM   14413 O O   . THR F 1 71  ? 2.842   -35.754 124.460 1.00 86.46  ? 90  THR F O   1 
ATOM   14414 C CB  . THR F 1 71  ? -0.276  -36.183 125.325 1.00 87.14  ? 90  THR F CB  1 
ATOM   14415 O OG1 . THR F 1 71  ? -1.636  -35.842 125.021 1.00 88.55  ? 90  THR F OG1 1 
ATOM   14416 C CG2 . THR F 1 71  ? 0.282   -35.093 126.203 1.00 84.08  ? 90  THR F CG2 1 
ATOM   14417 N N   . GLU F 1 72  ? 2.316   -37.938 124.450 1.00 88.41  ? 91  GLU F N   1 
ATOM   14418 C CA  . GLU F 1 72  ? 3.698   -38.314 124.726 1.00 87.23  ? 91  GLU F CA  1 
ATOM   14419 C C   . GLU F 1 72  ? 4.640   -37.832 123.629 1.00 88.64  ? 91  GLU F C   1 
ATOM   14420 O O   . GLU F 1 72  ? 5.784   -37.451 123.900 1.00 87.06  ? 91  GLU F O   1 
ATOM   14421 C CB  . GLU F 1 72  ? 3.833   -39.825 124.880 1.00 88.00  ? 91  GLU F CB  1 
ATOM   14422 C CG  . GLU F 1 72  ? 3.038   -40.434 126.023 1.00 86.72  ? 91  GLU F CG  1 
ATOM   14423 C CD  . GLU F 1 72  ? 1.824   -41.235 125.539 1.00 89.09  ? 91  GLU F CD  1 
ATOM   14424 O OE1 . GLU F 1 72  ? 1.133   -40.762 124.610 1.00 90.89  ? 91  GLU F OE1 1 
ATOM   14425 O OE2 . GLU F 1 72  ? 1.572   -42.335 126.089 1.00 89.32  ? 91  GLU F OE2 1 
ATOM   14426 N N   . ALA F 1 73  ? 4.192   -37.864 122.377 1.00 91.75  ? 92  ALA F N   1 
ATOM   14427 C CA  . ALA F 1 73  ? 5.074   -37.485 121.280 1.00 93.41  ? 92  ALA F CA  1 
ATOM   14428 C C   . ALA F 1 73  ? 5.182   -35.972 121.162 1.00 92.47  ? 92  ALA F C   1 
ATOM   14429 O O   . ALA F 1 73  ? 6.245   -35.444 120.822 1.00 92.33  ? 92  ALA F O   1 
ATOM   14430 C CB  . ALA F 1 73  ? 4.575   -38.093 119.969 1.00 97.12  ? 92  ALA F CB  1 
ATOM   14431 N N   . GLY F 1 74  ? 4.088   -35.265 121.436 1.00 92.09  ? 93  GLY F N   1 
ATOM   14432 C CA  . GLY F 1 74  ? 4.134   -33.818 121.384 1.00 91.33  ? 93  GLY F CA  1 
ATOM   14433 C C   . GLY F 1 74  ? 5.017   -33.240 122.471 1.00 87.91  ? 93  GLY F C   1 
ATOM   14434 O O   . GLY F 1 74  ? 5.860   -32.377 122.210 1.00 87.48  ? 93  GLY F O   1 
ATOM   14435 N N   . ILE F 1 75  ? 4.845   -33.715 123.704 1.00 87.46  ? 94  ILE F N   1 
ATOM   14436 C CA  . ILE F 1 75  ? 5.573   -33.116 124.813 1.00 84.19  ? 94  ILE F CA  1 
ATOM   14437 C C   . ILE F 1 75  ? 7.073   -33.290 124.612 1.00 84.05  ? 94  ILE F C   1 
ATOM   14438 O O   . ILE F 1 75  ? 7.860   -32.364 124.848 1.00 82.85  ? 94  ILE F O   1 
ATOM   14439 C CB  . ILE F 1 75  ? 5.100   -33.704 126.157 1.00 81.68  ? 94  ILE F CB  1 
ATOM   14440 C CG1 . ILE F 1 75  ? 3.705   -33.169 126.503 1.00 81.48  ? 94  ILE F CG1 1 
ATOM   14441 C CG2 . ILE F 1 75  ? 6.107   -33.360 127.271 1.00 78.87  ? 94  ILE F CG2 1 
ATOM   14442 C CD1 . ILE F 1 75  ? 3.291   -33.359 127.965 1.00 79.45  ? 94  ILE F CD1 1 
ATOM   14443 N N   . GLU F 1 76  ? 7.497   -34.480 124.186 1.00 85.10  ? 95  GLU F N   1 
ATOM   14444 C CA  . GLU F 1 76  ? 8.925   -34.707 123.978 1.00 85.72  ? 95  GLU F CA  1 
ATOM   14445 C C   . GLU F 1 76  ? 9.499   -33.660 123.027 1.00 87.84  ? 95  GLU F C   1 
ATOM   14446 O O   . GLU F 1 76  ? 10.578  -33.102 123.285 1.00 87.25  ? 95  GLU F O   1 
ATOM   14447 C CB  . GLU F 1 76  ? 9.140   -36.137 123.476 1.00 87.79  ? 95  GLU F CB  1 
ATOM   14448 C CG  . GLU F 1 76  ? 10.567  -36.514 123.110 1.00 89.49  ? 95  GLU F CG  1 
ATOM   14449 C CD  . GLU F 1 76  ? 11.517  -36.605 124.292 1.00 87.17  ? 95  GLU F CD  1 
ATOM   14450 O OE1 . GLU F 1 76  ? 11.060  -36.738 125.456 1.00 84.44  ? 95  GLU F OE1 1 
ATOM   14451 O OE2 . GLU F 1 76  ? 12.744  -36.559 124.044 1.00 88.79  ? 95  GLU F OE2 1 
ATOM   14452 N N   . ALA F 1 77  ? 8.747   -33.327 121.965 1.00 88.87  ? 96  ALA F N   1 
ATOM   14453 C CA  . ALA F 1 77  ? 9.221   -32.371 120.971 1.00 91.20  ? 96  ALA F CA  1 
ATOM   14454 C C   . ALA F 1 77  ? 9.162   -30.936 121.494 1.00 89.27  ? 96  ALA F C   1 
ATOM   14455 O O   . ALA F 1 77  ? 10.050  -30.120 121.201 1.00 90.27  ? 96  ALA F O   1 
ATOM   14456 C CB  . ALA F 1 77  ? 8.398   -32.509 119.687 1.00 94.29  ? 96  ALA F CB  1 
ATOM   14457 N N   . GLU F 1 78  ? 8.110   -30.591 122.239 1.00 88.26  ? 97  GLU F N   1 
ATOM   14458 C CA  . GLU F 1 78  ? 8.083   -29.270 122.849 1.00 86.38  ? 97  GLU F CA  1 
ATOM   14459 C C   . GLU F 1 78  ? 9.226   -29.138 123.849 1.00 84.20  ? 97  GLU F C   1 
ATOM   14460 O O   . GLU F 1 78  ? 9.900   -28.111 123.895 1.00 84.36  ? 97  GLU F O   1 
ATOM   14461 C CB  . GLU F 1 78  ? 6.724   -29.016 123.500 1.00 84.18  ? 97  GLU F CB  1 
ATOM   14462 N N   . ALA F 1 79  ? 9.504   -30.191 124.614 1.00 83.64  ? 98  ALA F N   1 
ATOM   14463 C CA  . ALA F 1 79  ? 10.604  -30.125 125.568 1.00 81.72  ? 98  ALA F CA  1 
ATOM   14464 C C   . ALA F 1 79  ? 11.933  -29.876 124.873 1.00 83.88  ? 98  ALA F C   1 
ATOM   14465 O O   . ALA F 1 79  ? 12.750  -29.086 125.341 1.00 83.35  ? 98  ALA F O   1 
ATOM   14466 C CB  . ALA F 1 79  ? 10.684  -31.421 126.378 1.00 80.50  ? 98  ALA F CB  1 
ATOM   14467 N N   . ARG F 1 80  ? 12.191  -30.583 123.777 1.00 84.36  ? 99  ARG F N   1 
ATOM   14468 C CA  . ARG F 1 80  ? 13.487  -30.455 123.127 1.00 86.78  ? 99  ARG F CA  1 
ATOM   14469 C C   . ARG F 1 80  ? 13.654  -29.095 122.475 1.00 87.97  ? 99  ARG F C   1 
ATOM   14470 O O   . ARG F 1 80  ? 14.776  -28.582 122.386 1.00 88.52  ? 99  ARG F O   1 
ATOM   14471 C CB  . ARG F 1 80  ? 13.664  -31.535 122.064 1.00 90.07  ? 99  ARG F CB  1 
ATOM   14472 C CG  . ARG F 1 80  ? 14.289  -32.836 122.538 1.00 89.51  ? 99  ARG F CG  1 
ATOM   14473 C CD  . ARG F 1 80  ? 15.352  -33.278 121.518 1.00 93.02  ? 99  ARG F CD  1 
ATOM   14474 N NE  . ARG F 1 80  ? 15.903  -34.632 121.664 1.00 93.94  ? 99  ARG F NE  1 
ATOM   14475 C CZ  . ARG F 1 80  ? 15.213  -35.773 121.672 1.00 95.09  ? 99  ARG F CZ  1 
ATOM   14476 N NH1 . ARG F 1 80  ? 13.890  -35.785 121.618 1.00 94.75  ? 99  ARG F NH1 1 
ATOM   14477 N NH2 . ARG F 1 80  ? 15.872  -36.933 121.740 1.00 97.03  ? 99  ARG F NH2 1 
ATOM   14478 N N   . GLN F 1 81  ? 12.564  -28.508 121.980 1.00 88.87  ? 100 GLN F N   1 
ATOM   14479 C CA  . GLN F 1 81  ? 12.670  -27.160 121.424 1.00 90.31  ? 100 GLN F CA  1 
ATOM   14480 C C   . GLN F 1 81  ? 12.821  -26.116 122.529 1.00 87.29  ? 100 GLN F C   1 
ATOM   14481 O O   . GLN F 1 81  ? 13.553  -25.139 122.350 1.00 88.04  ? 100 GLN F O   1 
ATOM   14482 C CB  . GLN F 1 81  ? 11.472  -26.863 120.507 1.00 92.26  ? 100 GLN F CB  1 
ATOM   14483 C CG  . GLN F 1 81  ? 10.153  -26.574 121.198 1.00 89.86  ? 100 GLN F CG  1 
ATOM   14484 C CD  . GLN F 1 81  ? 9.094   -25.977 120.246 1.00 92.28  ? 100 GLN F CD  1 
ATOM   14485 O OE1 . GLN F 1 81  ? 9.409   -25.295 119.255 1.00 95.33  ? 100 GLN F OE1 1 
ATOM   14486 N NE2 . GLN F 1 81  ? 7.823   -26.234 120.570 1.00 91.08  ? 100 GLN F NE2 1 
ATOM   14487 N N   . LEU F 1 82  ? 12.183  -26.324 123.685 1.00 86.34  ? 101 LEU F N   1 
ATOM   14488 C CA  . LEU F 1 82  ? 12.315  -25.377 124.784 1.00 83.43  ? 101 LEU F CA  1 
ATOM   14489 C C   . LEU F 1 82  ? 13.693  -25.450 125.430 1.00 82.49  ? 101 LEU F C   1 
ATOM   14490 O O   . LEU F 1 82  ? 14.284  -24.415 125.759 1.00 82.73  ? 101 LEU F O   1 
ATOM   14491 C CB  . LEU F 1 82  ? 11.256  -25.640 125.850 1.00 80.05  ? 101 LEU F CB  1 
ATOM   14492 C CG  . LEU F 1 82  ? 9.797   -25.333 125.541 1.00 80.36  ? 101 LEU F CG  1 
ATOM   14493 C CD1 . LEU F 1 82  ? 8.970   -25.686 126.780 1.00 77.25  ? 101 LEU F CD1 1 
ATOM   14494 C CD2 . LEU F 1 82  ? 9.572   -23.901 125.142 1.00 82.16  ? 101 LEU F CD2 1 
ATOM   14495 N N   . LYS F 1 83  ? 14.203  -26.665 125.662 1.00 81.08  ? 102 LYS F N   1 
ATOM   14496 C CA  . LYS F 1 83  ? 15.493  -26.812 126.334 1.00 81.83  ? 102 LYS F CA  1 
ATOM   14497 C C   . LYS F 1 83  ? 16.645  -26.480 125.401 1.00 86.12  ? 102 LYS F C   1 
ATOM   14498 O O   . LYS F 1 83  ? 17.714  -26.041 125.848 1.00 87.57  ? 102 LYS F O   1 
ATOM   14499 C CB  . LYS F 1 83  ? 15.666  -28.237 126.854 1.00 80.97  ? 102 LYS F CB  1 
ATOM   14500 C CG  . LYS F 1 83  ? 14.609  -28.695 127.820 1.00 77.37  ? 102 LYS F CG  1 
ATOM   14501 C CD  . LYS F 1 83  ? 15.229  -29.621 128.881 1.00 77.42  ? 102 LYS F CD  1 
ATOM   14502 C CE  . LYS F 1 83  ? 14.552  -30.977 128.978 1.00 75.60  ? 102 LYS F CE  1 
ATOM   14503 N NZ  . LYS F 1 83  ? 15.181  -31.760 130.082 1.00 74.68  ? 102 LYS F NZ  1 
ATOM   14504 N N   . ASN F 1 84  ? 16.460  -26.724 124.114 1.00 85.40  ? 103 ASN F N   1 
ATOM   14505 C CA  . ASN F 1 84  ? 17.411  -26.226 123.140 1.00 88.57  ? 103 ASN F CA  1 
ATOM   14506 C C   . ASN F 1 84  ? 17.573  -24.717 123.262 1.00 88.22  ? 103 ASN F C   1 
ATOM   14507 O O   . ASN F 1 84  ? 18.666  -24.198 123.019 1.00 89.73  ? 103 ASN F O   1 
ATOM   14508 C CB  . ASN F 1 84  ? 16.952  -26.625 121.742 1.00 92.09  ? 103 ASN F CB  1 
ATOM   14509 C CG  . ASN F 1 84  ? 17.809  -26.023 120.671 1.00 95.64  ? 103 ASN F CG  1 
ATOM   14510 O OD1 . ASN F 1 84  ? 18.943  -26.449 120.464 1.00 97.06  ? 103 ASN F OD1 1 
ATOM   14511 N ND2 . ASN F 1 84  ? 17.284  -25.004 119.991 1.00 97.04  ? 103 ASN F ND2 1 
ATOM   14512 N N   . LEU F 1 85  ? 16.513  -23.999 123.662 1.00 86.49  ? 104 LEU F N   1 
ATOM   14513 C CA  . LEU F 1 85  ? 16.593  -22.549 123.849 1.00 86.00  ? 104 LEU F CA  1 
ATOM   14514 C C   . LEU F 1 85  ? 17.006  -22.158 125.269 1.00 82.66  ? 104 LEU F C   1 
ATOM   14515 O O   . LEU F 1 85  ? 17.786  -21.218 125.448 1.00 83.25  ? 104 LEU F O   1 
ATOM   14516 C CB  . LEU F 1 85  ? 15.252  -21.864 123.541 1.00 85.61  ? 104 LEU F CB  1 
ATOM   14517 C CG  . LEU F 1 85  ? 14.679  -21.959 122.125 1.00 89.39  ? 104 LEU F CG  1 
ATOM   14518 C CD1 . LEU F 1 85  ? 13.271  -21.365 122.124 1.00 88.48  ? 104 LEU F CD1 1 
ATOM   14519 C CD2 . LEU F 1 85  ? 15.595  -21.276 121.117 1.00 93.06  ? 104 LEU F CD2 1 
ATOM   14520 N N   . ASN F 1 86  ? 16.466  -22.835 126.282 1.00 84.50  ? 105 ASN F N   1 
ATOM   14521 C CA  . ASN F 1 86  ? 16.814  -22.602 127.685 1.00 80.48  ? 105 ASN F CA  1 
ATOM   14522 C C   . ASN F 1 86  ? 17.204  -23.963 128.256 1.00 78.51  ? 105 ASN F C   1 
ATOM   14523 O O   . ASN F 1 86  ? 16.336  -24.796 128.576 1.00 77.41  ? 105 ASN F O   1 
ATOM   14524 C CB  . ASN F 1 86  ? 15.665  -21.946 128.452 1.00 78.41  ? 105 ASN F CB  1 
ATOM   14525 C CG  . ASN F 1 86  ? 15.930  -21.821 129.966 1.00 74.08  ? 105 ASN F CG  1 
ATOM   14526 O OD1 . ASN F 1 86  ? 16.996  -22.179 130.469 1.00 72.58  ? 105 ASN F OD1 1 
ATOM   14527 N ND2 . ASN F 1 86  ? 14.939  -21.308 130.688 1.00 72.24  ? 105 ASN F ND2 1 
ATOM   14528 N N   . PRO F 1 87  ? 18.501  -24.243 128.362 1.00 80.85  ? 106 PRO F N   1 
ATOM   14529 C CA  . PRO F 1 87  ? 18.927  -25.506 128.973 1.00 79.24  ? 106 PRO F CA  1 
ATOM   14530 C C   . PRO F 1 87  ? 18.606  -25.612 130.453 1.00 75.57  ? 106 PRO F C   1 
ATOM   14531 O O   . PRO F 1 87  ? 18.626  -26.724 130.991 1.00 75.02  ? 106 PRO F O   1 
ATOM   14532 C CB  . PRO F 1 87  ? 20.443  -25.528 128.742 1.00 80.13  ? 106 PRO F CB  1 
ATOM   14533 C CG  . PRO F 1 87  ? 20.785  -24.334 127.957 1.00 82.38  ? 106 PRO F CG  1 
ATOM   14534 C CD  . PRO F 1 87  ? 19.613  -23.444 127.819 1.00 82.65  ? 106 PRO F CD  1 
ATOM   14535 N N   . LYS F 1 88  ? 18.331  -24.513 131.137 1.00 74.02  ? 107 LYS F N   1 
ATOM   14536 C CA  . LYS F 1 88  ? 17.976  -24.608 132.544 1.00 71.57  ? 107 LYS F CA  1 
ATOM   14537 C C   . LYS F 1 88  ? 16.510  -24.947 132.750 1.00 70.07  ? 107 LYS F C   1 
ATOM   14538 O O   . LYS F 1 88  ? 16.071  -25.006 133.905 1.00 67.82  ? 107 LYS F O   1 
ATOM   14539 C CB  . LYS F 1 88  ? 18.313  -23.296 133.262 1.00 70.96  ? 107 LYS F CB  1 
ATOM   14540 N N   . MET F 1 89  ? 15.756  -25.184 131.674 1.00 70.78  ? 108 MET F N   1 
ATOM   14541 C CA  . MET F 1 89  ? 14.317  -25.343 131.797 1.00 70.52  ? 108 MET F CA  1 
ATOM   14542 C C   . MET F 1 89  ? 13.931  -26.751 132.224 1.00 69.44  ? 108 MET F C   1 
ATOM   14543 O O   . MET F 1 89  ? 14.278  -27.745 131.566 1.00 71.12  ? 108 MET F O   1 
ATOM   14544 C CB  . MET F 1 89  ? 13.585  -25.037 130.499 1.00 74.01  ? 108 MET F CB  1 
ATOM   14545 C CG  . MET F 1 89  ? 12.185  -24.548 130.797 1.00 73.29  ? 108 MET F CG  1 
ATOM   14546 S SD  . MET F 1 89  ? 11.627  -23.221 129.730 1.00 76.66  ? 108 MET F SD  1 
ATOM   14547 C CE  . MET F 1 89  ? 10.076  -22.817 130.532 1.00 77.28  ? 108 MET F CE  1 
ATOM   14548 N N   . LYS F 1 90  ? 13.167  -26.816 133.302 1.00 68.06  ? 109 LYS F N   1 
ATOM   14549 C CA  . LYS F 1 90  ? 12.579  -28.045 133.805 1.00 67.20  ? 109 LYS F CA  1 
ATOM   14550 C C   . LYS F 1 90  ? 11.224  -28.227 133.142 1.00 68.73  ? 109 LYS F C   1 
ATOM   14551 O O   . LYS F 1 90  ? 10.343  -27.363 133.272 1.00 68.78  ? 109 LYS F O   1 
ATOM   14552 C CB  . LYS F 1 90  ? 12.481  -27.956 135.322 1.00 64.55  ? 109 LYS F CB  1 
ATOM   14553 C CG  . LYS F 1 90  ? 13.851  -27.765 135.961 1.00 64.93  ? 109 LYS F CG  1 
ATOM   14554 C CD  . LYS F 1 90  ? 14.722  -28.951 135.655 1.00 66.09  ? 109 LYS F CD  1 
ATOM   14555 C CE  . LYS F 1 90  ? 16.008  -28.888 136.407 1.00 64.52  ? 109 LYS F CE  1 
ATOM   14556 N NZ  . LYS F 1 90  ? 16.715  -30.186 136.176 1.00 64.37  ? 109 LYS F NZ  1 
ATOM   14557 N N   . VAL F 1 91  ? 11.073  -29.313 132.387 1.00 68.75  ? 110 VAL F N   1 
ATOM   14558 C CA  . VAL F 1 91  ? 9.870   -29.542 131.598 1.00 74.30  ? 110 VAL F CA  1 
ATOM   14559 C C   . VAL F 1 91  ? 9.142   -30.755 132.151 1.00 73.97  ? 110 VAL F C   1 
ATOM   14560 O O   . VAL F 1 91  ? 9.689   -31.866 132.192 1.00 73.96  ? 110 VAL F O   1 
ATOM   14561 C CB  . VAL F 1 91  ? 10.191  -29.711 130.107 1.00 77.65  ? 110 VAL F CB  1 
ATOM   14562 C CG1 . VAL F 1 91  ? 8.915   -29.963 129.302 1.00 80.88  ? 110 VAL F CG1 1 
ATOM   14563 C CG2 . VAL F 1 91  ? 10.933  -28.467 129.603 1.00 76.71  ? 110 VAL F CG2 1 
ATOM   14564 N N   . ILE F 1 92  ? 7.894   -30.543 132.530 1.00 73.50  ? 111 ILE F N   1 
ATOM   14565 C CA  . ILE F 1 92  ? 7.089   -31.519 133.246 1.00 72.38  ? 111 ILE F CA  1 
ATOM   14566 C C   . ILE F 1 92  ? 6.092   -32.176 132.302 1.00 75.15  ? 111 ILE F C   1 
ATOM   14567 O O   . ILE F 1 92  ? 5.431   -31.502 131.484 1.00 76.97  ? 111 ILE F O   1 
ATOM   14568 C CB  . ILE F 1 92  ? 6.376   -30.831 134.428 1.00 69.73  ? 111 ILE F CB  1 
ATOM   14569 C CG1 . ILE F 1 92  ? 7.415   -30.144 135.330 1.00 67.08  ? 111 ILE F CG1 1 
ATOM   14570 C CG2 . ILE F 1 92  ? 5.574   -31.822 135.229 1.00 68.82  ? 111 ILE F CG2 1 
ATOM   14571 C CD1 . ILE F 1 92  ? 8.486   -31.132 135.873 1.00 65.72  ? 111 ILE F CD1 1 
ATOM   14572 N N   . PHE F 1 93  ? 5.980   -33.506 132.429 1.00 75.62  ? 112 PHE F N   1 
ATOM   14573 C CA  . PHE F 1 93  ? 5.044   -34.315 131.648 1.00 78.17  ? 112 PHE F CA  1 
ATOM   14574 C C   . PHE F 1 93  ? 3.751   -34.492 132.442 1.00 77.26  ? 112 PHE F C   1 
ATOM   14575 O O   . PHE F 1 93  ? 3.772   -35.016 133.564 1.00 75.05  ? 112 PHE F O   1 
ATOM   14576 C CB  . PHE F 1 93  ? 5.677   -35.671 131.313 1.00 79.20  ? 112 PHE F CB  1 
ATOM   14577 C CG  . PHE F 1 93  ? 4.744   -36.616 130.614 1.00 81.70  ? 112 PHE F CG  1 
ATOM   14578 C CD1 . PHE F 1 93  ? 3.935   -37.480 131.340 1.00 81.07  ? 112 PHE F CD1 1 
ATOM   14579 C CD2 . PHE F 1 93  ? 4.668   -36.634 129.230 1.00 84.89  ? 112 PHE F CD2 1 
ATOM   14580 C CE1 . PHE F 1 93  ? 3.080   -38.329 130.698 1.00 83.51  ? 112 PHE F CE1 1 
ATOM   14581 C CE2 . PHE F 1 93  ? 3.812   -37.478 128.594 1.00 87.27  ? 112 PHE F CE2 1 
ATOM   14582 C CZ  . PHE F 1 93  ? 3.013   -38.321 129.329 1.00 86.56  ? 112 PHE F CZ  1 
ATOM   14583 N N   . TYR F 1 94  ? 2.630   -34.038 131.879 1.00 79.12  ? 113 TYR F N   1 
ATOM   14584 C CA  . TYR F 1 94  ? 1.341   -34.254 132.530 1.00 78.70  ? 113 TYR F CA  1 
ATOM   14585 C C   . TYR F 1 94  ? 0.906   -35.723 132.372 1.00 79.98  ? 113 TYR F C   1 
ATOM   14586 O O   . TYR F 1 94  ? 0.692   -36.206 131.252 1.00 82.76  ? 113 TYR F O   1 
ATOM   14587 C CB  . TYR F 1 94  ? 0.278   -33.311 131.954 1.00 80.51  ? 113 TYR F CB  1 
ATOM   14588 C CG  . TYR F 1 94  ? -1.106  -33.476 132.580 1.00 80.25  ? 113 TYR F CG  1 
ATOM   14589 C CD1 . TYR F 1 94  ? -1.952  -34.509 132.196 1.00 82.21  ? 113 TYR F CD1 1 
ATOM   14590 C CD2 . TYR F 1 94  ? -1.560  -32.609 133.563 1.00 78.30  ? 113 TYR F CD2 1 
ATOM   14591 C CE1 . TYR F 1 94  ? -3.201  -34.663 132.766 1.00 82.22  ? 113 TYR F CE1 1 
ATOM   14592 C CE2 . TYR F 1 94  ? -2.822  -32.770 134.140 1.00 78.34  ? 113 TYR F CE2 1 
ATOM   14593 C CZ  . TYR F 1 94  ? -3.633  -33.798 133.733 1.00 80.34  ? 113 TYR F CZ  1 
ATOM   14594 O OH  . TYR F 1 94  ? -4.885  -33.975 134.283 1.00 80.59  ? 113 TYR F OH  1 
ATOM   14595 N N   . TRP F 1 95  ? 0.754   -36.422 133.497 1.00 78.17  ? 114 TRP F N   1 
ATOM   14596 C CA  . TRP F 1 95  ? 0.309   -37.816 133.524 1.00 79.20  ? 114 TRP F CA  1 
ATOM   14597 C C   . TRP F 1 95  ? -0.697  -37.906 134.669 1.00 77.91  ? 114 TRP F C   1 
ATOM   14598 O O   . TRP F 1 95  ? -0.326  -37.846 135.838 1.00 75.29  ? 114 TRP F O   1 
ATOM   14599 C CB  . TRP F 1 95  ? 1.496   -38.743 133.700 1.00 78.34  ? 114 TRP F CB  1 
ATOM   14600 C CG  . TRP F 1 95  ? 1.247   -40.223 133.641 1.00 79.83  ? 114 TRP F CG  1 
ATOM   14601 C CD1 . TRP F 1 95  ? 1.949   -41.182 134.329 1.00 78.48  ? 114 TRP F CD1 1 
ATOM   14602 C CD2 . TRP F 1 95  ? 0.282   -40.938 132.856 1.00 83.04  ? 114 TRP F CD2 1 
ATOM   14603 N NE1 . TRP F 1 95  ? 1.475   -42.444 134.022 1.00 80.54  ? 114 TRP F NE1 1 
ATOM   14604 C CE2 . TRP F 1 95  ? 0.455   -42.317 133.124 1.00 83.33  ? 114 TRP F CE2 1 
ATOM   14605 C CE3 . TRP F 1 95  ? -0.709  -40.559 131.966 1.00 85.75  ? 114 TRP F CE3 1 
ATOM   14606 C CZ2 . TRP F 1 95  ? -0.324  -43.301 132.525 1.00 86.17  ? 114 TRP F CZ2 1 
ATOM   14607 C CZ3 . TRP F 1 95  ? -1.484  -41.546 131.387 1.00 88.57  ? 114 TRP F CZ3 1 
ATOM   14608 C CH2 . TRP F 1 95  ? -1.290  -42.896 131.663 1.00 88.70  ? 114 TRP F CH2 1 
ATOM   14609 N N   . ASN F 1 96  ? -1.977  -37.982 134.337 1.00 79.79  ? 115 ASN F N   1 
ATOM   14610 C CA  . ASN F 1 96  ? -3.010  -38.003 135.363 1.00 78.80  ? 115 ASN F CA  1 
ATOM   14611 C C   . ASN F 1 96  ? -2.937  -39.319 136.140 1.00 78.15  ? 115 ASN F C   1 
ATOM   14612 O O   . ASN F 1 96  ? -2.829  -40.408 135.561 1.00 79.96  ? 115 ASN F O   1 
ATOM   14613 C CB  . ASN F 1 96  ? -4.390  -37.794 134.726 1.00 81.32  ? 115 ASN F CB  1 
ATOM   14614 C CG  . ASN F 1 96  ? -5.427  -37.311 135.723 1.00 80.38  ? 115 ASN F CG  1 
ATOM   14615 O OD1 . ASN F 1 96  ? -5.782  -38.034 136.649 1.00 79.82  ? 115 ASN F OD1 1 
ATOM   14616 N ND2 . ASN F 1 96  ? -5.930  -36.081 135.529 1.00 80.42  ? 115 ASN F ND2 1 
ATOM   14617 N N   . THR F 1 97  ? -2.966  -39.212 137.466 1.00 75.68  ? 116 THR F N   1 
ATOM   14618 C CA  . THR F 1 97  ? -2.825  -40.372 138.342 1.00 74.85  ? 116 THR F CA  1 
ATOM   14619 C C   . THR F 1 97  ? -4.086  -41.230 138.373 1.00 76.78  ? 116 THR F C   1 
ATOM   14620 O O   . THR F 1 97  ? -4.027  -42.377 138.841 1.00 77.00  ? 116 THR F O   1 
ATOM   14621 C CB  . THR F 1 97  ? -2.478  -39.892 139.758 1.00 71.66  ? 116 THR F CB  1 
ATOM   14622 O OG1 . THR F 1 97  ? -1.557  -38.790 139.686 1.00 69.97  ? 116 THR F OG1 1 
ATOM   14623 C CG2 . THR F 1 97  ? -1.844  -40.981 140.568 1.00 70.65  ? 116 THR F CG2 1 
ATOM   14624 N N   . PHE F 1 98  ? -5.204  -40.718 137.844 1.00 78.41  ? 117 PHE F N   1 
ATOM   14625 C CA  . PHE F 1 98  ? -6.523  -41.263 138.145 1.00 80.01  ? 117 PHE F CA  1 
ATOM   14626 C C   . PHE F 1 98  ? -7.336  -41.537 136.895 1.00 83.28  ? 117 PHE F C   1 
ATOM   14627 O O   . PHE F 1 98  ? -8.150  -42.461 136.883 1.00 85.03  ? 117 PHE F O   1 
ATOM   14628 C CB  . PHE F 1 98  ? -7.288  -40.278 139.039 1.00 78.64  ? 117 PHE F CB  1 
ATOM   14629 C CG  . PHE F 1 98  ? -8.417  -40.888 139.815 1.00 79.56  ? 117 PHE F CG  1 
ATOM   14630 C CD1 . PHE F 1 98  ? -8.427  -42.227 140.134 1.00 80.27  ? 117 PHE F CD1 1 
ATOM   14631 C CD2 . PHE F 1 98  ? -9.456  -40.099 140.255 1.00 79.71  ? 117 PHE F CD2 1 
ATOM   14632 C CE1 . PHE F 1 98  ? -9.452  -42.765 140.864 1.00 81.23  ? 117 PHE F CE1 1 
ATOM   14633 C CE2 . PHE F 1 98  ? -10.483 -40.641 140.985 1.00 80.68  ? 117 PHE F CE2 1 
ATOM   14634 C CZ  . PHE F 1 98  ? -10.483 -41.972 141.289 1.00 81.44  ? 117 PHE F CZ  1 
ATOM   14635 N N   . LEU F 1 99  ? -7.135  -40.732 135.852 1.00 84.29  ? 118 LEU F N   1 
ATOM   14636 C CA  . LEU F 1 99  ? -8.002  -40.732 134.685 1.00 87.38  ? 118 LEU F CA  1 
ATOM   14637 C C   . LEU F 1 99  ? -7.257  -41.172 133.441 1.00 89.01  ? 118 LEU F C   1 
ATOM   14638 O O   . LEU F 1 99  ? -6.156  -40.680 133.155 1.00 87.89  ? 118 LEU F O   1 
ATOM   14639 C CB  . LEU F 1 99  ? -8.591  -39.355 134.419 1.00 87.62  ? 118 LEU F CB  1 
ATOM   14640 C CG  . LEU F 1 99  ? -9.425  -38.771 135.551 1.00 86.09  ? 118 LEU F CG  1 
ATOM   14641 C CD1 . LEU F 1 99  ? -9.918  -37.367 135.147 1.00 86.50  ? 118 LEU F CD1 1 
ATOM   14642 C CD2 . LEU F 1 99  ? -10.555 -39.723 135.917 1.00 87.63  ? 118 LEU F CD2 1 
ATOM   14643 N N   . ASP F 1 100 ? -7.911  -42.066 132.696 1.00 91.89  ? 119 ASP F N   1 
ATOM   14644 C CA  . ASP F 1 100 ? -7.431  -42.653 131.454 1.00 93.99  ? 119 ASP F CA  1 
ATOM   14645 C C   . ASP F 1 100 ? -7.829  -41.714 130.320 1.00 95.95  ? 119 ASP F C   1 
ATOM   14646 O O   . ASP F 1 100 ? -8.835  -41.886 129.639 1.00 98.69  ? 119 ASP F O   1 
ATOM   14647 C CB  . ASP F 1 100 ? -8.022  -44.049 131.314 1.00 96.03  ? 119 ASP F CB  1 
ATOM   14648 C CG  . ASP F 1 100 ? -7.775  -44.663 129.971 1.00 98.73  ? 119 ASP F CG  1 
ATOM   14649 O OD1 . ASP F 1 100 ? -6.698  -44.408 129.397 1.00 98.40  ? 119 ASP F OD1 1 
ATOM   14650 O OD2 . ASP F 1 100 ? -8.670  -45.404 129.489 1.00 101.33 ? 119 ASP F OD2 1 
ATOM   14651 N N   . TYR F 1 101 ? -7.031  -40.670 130.142 1.00 94.62  ? 120 TYR F N   1 
ATOM   14652 C CA  . TYR F 1 101 ? -7.258  -39.761 129.030 1.00 96.60  ? 120 TYR F CA  1 
ATOM   14653 C C   . TYR F 1 101 ? -6.877  -40.447 127.722 1.00 99.34  ? 120 TYR F C   1 
ATOM   14654 O O   . TYR F 1 101 ? -5.927  -41.235 127.659 1.00 99.02  ? 120 TYR F O   1 
ATOM   14655 C CB  . TYR F 1 101 ? -6.458  -38.473 129.222 1.00 94.78  ? 120 TYR F CB  1 
ATOM   14656 C CG  . TYR F 1 101 ? -7.055  -37.526 130.258 1.00 92.77  ? 120 TYR F CG  1 
ATOM   14657 C CD1 . TYR F 1 101 ? -8.341  -37.019 130.112 1.00 94.18  ? 120 TYR F CD1 1 
ATOM   14658 C CD2 . TYR F 1 101 ? -6.326  -37.141 131.375 1.00 89.49  ? 120 TYR F CD2 1 
ATOM   14659 C CE1 . TYR F 1 101 ? -8.881  -36.137 131.040 1.00 92.43  ? 120 TYR F CE1 1 
ATOM   14660 C CE2 . TYR F 1 101 ? -6.855  -36.271 132.315 1.00 87.67  ? 120 TYR F CE2 1 
ATOM   14661 C CZ  . TYR F 1 101 ? -8.132  -35.767 132.149 1.00 89.19  ? 120 TYR F CZ  1 
ATOM   14662 O OH  . TYR F 1 101 ? -8.660  -34.896 133.084 1.00 87.63  ? 120 TYR F OH  1 
ATOM   14663 N N   . SER F 1 102 ? -7.636  -40.142 126.666 1.00 102.21 ? 121 SER F N   1 
ATOM   14664 C CA  . SER F 1 102 ? -7.490  -40.788 125.370 1.00 105.24 ? 121 SER F CA  1 
ATOM   14665 C C   . SER F 1 102 ? -6.595  -40.008 124.416 1.00 105.74 ? 121 SER F C   1 
ATOM   14666 O O   . SER F 1 102 ? -6.479  -40.395 123.250 1.00 107.80 ? 121 SER F O   1 
ATOM   14667 C CB  . SER F 1 102 ? -8.867  -40.990 124.741 1.00 108.18 ? 121 SER F CB  1 
ATOM   14668 O OG  . SER F 1 102 ? -9.513  -39.735 124.612 1.00 108.52 ? 121 SER F OG  1 
ATOM   14669 N N   . MET F 1 103 ? -5.966  -38.924 124.874 1.00 104.14 ? 122 MET F N   1 
ATOM   14670 C CA  . MET F 1 103 ? -4.993  -38.207 124.059 1.00 105.07 ? 122 MET F CA  1 
ATOM   14671 C C   . MET F 1 103 ? -3.596  -38.807 124.126 1.00 103.12 ? 122 MET F C   1 
ATOM   14672 O O   . MET F 1 103 ? -2.690  -38.284 123.463 1.00 102.86 ? 122 MET F O   1 
ATOM   14673 C CB  . MET F 1 103 ? -4.863  -36.730 124.468 1.00 104.69 ? 122 MET F CB  1 
ATOM   14674 C CG  . MET F 1 103 ? -6.148  -36.048 124.842 1.00 101.00 ? 122 MET F CG  1 
ATOM   14675 S SD  . MET F 1 103 ? -6.583  -36.561 126.496 1.00 100.79 ? 122 MET F SD  1 
ATOM   14676 C CE  . MET F 1 103 ? -7.968  -35.503 126.902 1.00 101.85 ? 122 MET F CE  1 
ATOM   14677 N N   . PHE F 1 104 ? -3.385  -39.835 124.946 1.00 102.28 ? 123 PHE F N   1 
ATOM   14678 C CA  . PHE F 1 104 ? -2.074  -40.434 125.135 1.00 100.89 ? 123 PHE F CA  1 
ATOM   14679 C C   . PHE F 1 104 ? -2.035  -41.785 124.438 1.00 103.23 ? 123 PHE F C   1 
ATOM   14680 O O   . PHE F 1 104 ? -3.026  -42.523 124.455 1.00 104.38 ? 123 PHE F O   1 
ATOM   14681 C CB  . PHE F 1 104 ? -1.736  -40.640 126.615 1.00 97.50  ? 123 PHE F CB  1 
ATOM   14682 C CG  . PHE F 1 104 ? -1.744  -39.396 127.439 1.00 94.93  ? 123 PHE F CG  1 
ATOM   14683 C CD1 . PHE F 1 104 ? -2.939  -38.806 127.820 1.00 94.89  ? 123 PHE F CD1 1 
ATOM   14684 C CD2 . PHE F 1 104 ? -0.550  -38.830 127.865 1.00 92.63  ? 123 PHE F CD2 1 
ATOM   14685 C CE1 . PHE F 1 104 ? -2.941  -37.658 128.595 1.00 92.63  ? 123 PHE F CE1 1 
ATOM   14686 C CE2 . PHE F 1 104 ? -0.552  -37.706 128.640 1.00 90.31  ? 123 PHE F CE2 1 
ATOM   14687 C CZ  . PHE F 1 104 ? -1.753  -37.117 129.004 1.00 90.32  ? 123 PHE F CZ  1 
ATOM   14688 N N   . ALA F 1 105 ? -0.878  -42.119 123.865 1.00 92.86  ? 124 ALA F N   1 
ATOM   14689 C CA  . ALA F 1 105 ? -0.659  -43.463 123.342 1.00 93.55  ? 124 ALA F CA  1 
ATOM   14690 C C   . ALA F 1 105 ? -0.906  -44.526 124.402 1.00 92.51  ? 124 ALA F C   1 
ATOM   14691 O O   . ALA F 1 105 ? -1.380  -45.624 124.098 1.00 93.56  ? 124 ALA F O   1 
ATOM   14692 C CB  . ALA F 1 105 ? 0.770   -43.611 122.811 1.00 93.22  ? 124 ALA F CB  1 
ATOM   14693 N N   . ALA F 1 106 ? -0.552  -44.227 125.658 1.00 90.58  ? 125 ALA F N   1 
ATOM   14694 C CA  . ALA F 1 106 ? -0.723  -45.196 126.739 1.00 89.58  ? 125 ALA F CA  1 
ATOM   14695 C C   . ALA F 1 106 ? -2.167  -45.677 126.848 1.00 90.80  ? 125 ALA F C   1 
ATOM   14696 O O   . ALA F 1 106 ? -2.423  -46.791 127.335 1.00 90.83  ? 125 ALA F O   1 
ATOM   14697 C CB  . ALA F 1 106 ? -0.270  -44.575 128.061 1.00 87.51  ? 125 ALA F CB  1 
ATOM   14698 N N   . HIS F 1 107 ? -3.127  -44.857 126.380 1.00 92.00  ? 126 HIS F N   1 
ATOM   14699 C CA  . HIS F 1 107 ? -4.541  -45.215 126.461 1.00 93.38  ? 126 HIS F CA  1 
ATOM   14700 C C   . HIS F 1 107 ? -4.862  -46.513 125.728 1.00 94.93  ? 126 HIS F C   1 
ATOM   14701 O O   . HIS F 1 107 ? -5.683  -47.320 126.193 1.00 95.48  ? 126 HIS F O   1 
ATOM   14702 C CB  . HIS F 1 107 ? -5.385  -44.116 125.860 1.00 94.80  ? 126 HIS F CB  1 
ATOM   14703 C CG  . HIS F 1 107 ? -6.847  -44.400 125.909 1.00 96.60  ? 126 HIS F CG  1 
ATOM   14704 N ND1 . HIS F 1 107 ? -7.572  -44.293 127.075 1.00 96.17  ? 126 HIS F ND1 1 
ATOM   14705 C CD2 . HIS F 1 107 ? -7.720  -44.792 124.952 1.00 98.96  ? 126 HIS F CD2 1 
ATOM   14706 C CE1 . HIS F 1 107 ? -8.835  -44.584 126.831 1.00 98.26  ? 126 HIS F CE1 1 
ATOM   14707 N NE2 . HIS F 1 107 ? -8.951  -44.893 125.552 1.00 99.96  ? 126 HIS F NE2 1 
ATOM   14708 N N   . LYS F 1 108 ? -4.285  -46.690 124.542 1.00 95.94  ? 127 LYS F N   1 
ATOM   14709 C CA  . LYS F 1 108 ? -4.509  -47.911 123.785 1.00 97.52  ? 127 LYS F CA  1 
ATOM   14710 C C   . LYS F 1 108 ? -3.819  -49.095 124.445 1.00 96.41  ? 127 LYS F C   1 
ATOM   14711 O O   . LYS F 1 108 ? -4.156  -50.242 124.142 1.00 97.56  ? 127 LYS F O   1 
ATOM   14712 C CB  . LYS F 1 108 ? -4.033  -47.735 122.342 1.00 99.11  ? 127 LYS F CB  1 
ATOM   14713 N N   . GLU F 1 109 ? -2.882  -48.849 125.361 1.00 94.30  ? 128 GLU F N   1 
ATOM   14714 C CA  . GLU F 1 109 ? -2.317  -49.948 126.138 1.00 93.25  ? 128 GLU F CA  1 
ATOM   14715 C C   . GLU F 1 109 ? -3.204  -50.300 127.329 1.00 92.96  ? 128 GLU F C   1 
ATOM   14716 O O   . GLU F 1 109 ? -3.407  -51.481 127.620 1.00 93.53  ? 128 GLU F O   1 
ATOM   14717 C CB  . GLU F 1 109 ? -0.906  -49.586 126.599 1.00 91.35  ? 128 GLU F CB  1 
ATOM   14718 C CG  . GLU F 1 109 ? 0.177   -50.151 125.693 1.00 91.84  ? 128 GLU F CG  1 
ATOM   14719 C CD  . GLU F 1 109 ? 0.481   -51.629 125.972 1.00 92.11  ? 128 GLU F CD  1 
ATOM   14720 O OE1 . GLU F 1 109 ? 0.642   -52.403 124.984 1.00 93.59  ? 128 GLU F OE1 1 
ATOM   14721 O OE2 . GLU F 1 109 ? 0.567   -52.018 127.173 1.00 90.97  ? 128 GLU F OE2 1 
ATOM   14722 N N   . TYR F 1 110 ? -3.744  -49.293 128.027 1.00 92.20  ? 129 TYR F N   1 
ATOM   14723 C CA  . TYR F 1 110 ? -4.667  -49.561 129.130 1.00 92.15  ? 129 TYR F CA  1 
ATOM   14724 C C   . TYR F 1 110 ? -5.915  -50.298 128.648 1.00 94.39  ? 129 TYR F C   1 
ATOM   14725 O O   . TYR F 1 110 ? -6.599  -50.934 129.462 1.00 94.73  ? 129 TYR F O   1 
ATOM   14726 C CB  . TYR F 1 110 ? -5.035  -48.240 129.845 1.00 91.26  ? 129 TYR F CB  1 
ATOM   14727 C CG  . TYR F 1 110 ? -5.917  -48.383 131.081 1.00 91.14  ? 129 TYR F CG  1 
ATOM   14728 C CD1 . TYR F 1 110 ? -5.422  -48.906 132.276 1.00 89.66  ? 129 TYR F CD1 1 
ATOM   14729 C CD2 . TYR F 1 110 ? -7.242  -47.984 131.051 1.00 92.64  ? 129 TYR F CD2 1 
ATOM   14730 C CE1 . TYR F 1 110 ? -6.246  -49.041 133.397 1.00 89.77  ? 129 TYR F CE1 1 
ATOM   14731 C CE2 . TYR F 1 110 ? -8.063  -48.110 132.159 1.00 92.78  ? 129 TYR F CE2 1 
ATOM   14732 C CZ  . TYR F 1 110 ? -7.571  -48.636 133.328 1.00 91.34  ? 129 TYR F CZ  1 
ATOM   14733 O OH  . TYR F 1 110 ? -8.423  -48.739 134.412 1.00 91.70  ? 129 TYR F OH  1 
ATOM   14734 N N   . ALA F 1 111 ? -6.215  -50.240 127.343 1.00 96.06  ? 130 ALA F N   1 
ATOM   14735 C CA  . ALA F 1 111 ? -7.395  -50.913 126.796 1.00 98.41  ? 130 ALA F CA  1 
ATOM   14736 C C   . ALA F 1 111 ? -7.218  -52.426 126.714 1.00 98.97  ? 130 ALA F C   1 
ATOM   14737 O O   . ALA F 1 111 ? -8.207  -53.155 126.608 1.00 100.73 ? 130 ALA F O   1 
ATOM   14738 C CB  . ALA F 1 111 ? -7.724  -50.363 125.399 1.00 100.10 ? 130 ALA F CB  1 
ATOM   14739 N N   . LYS F 1 112 ? -5.981  -52.903 126.782 1.00 97.65  ? 131 LYS F N   1 
ATOM   14740 C CA  . LYS F 1 112 ? -5.631  -54.300 126.595 1.00 98.25  ? 131 LYS F CA  1 
ATOM   14741 C C   . LYS F 1 112 ? -5.409  -55.032 127.916 1.00 97.15  ? 131 LYS F C   1 
ATOM   14742 O O   . LYS F 1 112 ? -4.881  -56.150 127.916 1.00 97.39  ? 131 LYS F O   1 
ATOM   14743 C CB  . LYS F 1 112 ? -4.373  -54.382 125.720 1.00 97.92  ? 131 LYS F CB  1 
ATOM   14744 C CG  . LYS F 1 112 ? -4.415  -53.487 124.484 1.00 98.87  ? 131 LYS F CG  1 
ATOM   14745 C CD  . LYS F 1 112 ? -3.055  -52.883 124.179 1.00 97.67  ? 131 LYS F CD  1 
ATOM   14746 C CE  . LYS F 1 112 ? -2.096  -53.913 123.641 1.00 98.03  ? 131 LYS F CE  1 
ATOM   14747 N NZ  . LYS F 1 112 ? -2.069  -53.828 122.157 1.00 99.85  ? 131 LYS F NZ  1 
ATOM   14748 N N   . HIS F 1 113 ? -5.801  -54.437 129.039 1.00 96.00  ? 132 HIS F N   1 
ATOM   14749 C CA  . HIS F 1 113 ? -5.639  -55.041 130.359 1.00 94.96  ? 132 HIS F CA  1 
ATOM   14750 C C   . HIS F 1 113 ? -6.930  -54.900 131.162 1.00 95.74  ? 132 HIS F C   1 
ATOM   14751 O O   . HIS F 1 113 ? -6.968  -54.182 132.173 1.00 94.51  ? 132 HIS F O   1 
ATOM   14752 C CB  . HIS F 1 113 ? -4.474  -54.412 131.115 1.00 92.60  ? 132 HIS F CB  1 
ATOM   14753 C CG  . HIS F 1 113 ? -3.142  -54.607 130.466 1.00 91.98  ? 132 HIS F CG  1 
ATOM   14754 N ND1 . HIS F 1 113 ? -2.401  -55.756 130.628 1.00 91.86  ? 132 HIS F ND1 1 
ATOM   14755 C CD2 . HIS F 1 113 ? -2.390  -53.778 129.700 1.00 91.55  ? 132 HIS F CD2 1 
ATOM   14756 C CE1 . HIS F 1 113 ? -1.258  -55.637 129.975 1.00 91.44  ? 132 HIS F CE1 1 
ATOM   14757 N NE2 . HIS F 1 113 ? -1.225  -54.445 129.406 1.00 91.24  ? 132 HIS F NE2 1 
ATOM   14758 N N   . PRO F 1 114 ? -8.002  -55.595 130.752 1.00 97.95  ? 133 PRO F N   1 
ATOM   14759 C CA  . PRO F 1 114 ? -9.269  -55.496 131.503 1.00 99.05  ? 133 PRO F CA  1 
ATOM   14760 C C   . PRO F 1 114 ? -9.225  -56.140 132.881 1.00 98.36  ? 133 PRO F C   1 
ATOM   14761 O O   . PRO F 1 114 ? -10.084 -55.826 133.715 1.00 98.92  ? 133 PRO F O   1 
ATOM   14762 C CB  . PRO F 1 114 ? -10.289 -56.196 130.592 1.00 101.75 ? 133 PRO F CB  1 
ATOM   14763 C CG  . PRO F 1 114 ? -9.592  -56.431 129.293 1.00 101.94 ? 133 PRO F CG  1 
ATOM   14764 C CD  . PRO F 1 114 ? -8.123  -56.423 129.540 1.00 99.65  ? 133 PRO F CD  1 
ATOM   14765 N N   . GLN F 1 115 ? -8.262  -57.025 133.157 1.00 97.42  ? 134 GLN F N   1 
ATOM   14766 C CA  . GLN F 1 115 ? -8.112  -57.515 134.521 1.00 96.72  ? 134 GLN F CA  1 
ATOM   14767 C C   . GLN F 1 115 ? -7.833  -56.371 135.497 1.00 94.87  ? 134 GLN F C   1 
ATOM   14768 O O   . GLN F 1 115 ? -8.064  -56.527 136.703 1.00 94.68  ? 134 GLN F O   1 
ATOM   14769 C CB  . GLN F 1 115 ? -7.006  -58.569 134.576 1.00 96.09  ? 134 GLN F CB  1 
ATOM   14770 N N   . TRP F 1 116 ? -7.364  -55.217 135.003 1.00 93.65  ? 135 TRP F N   1 
ATOM   14771 C CA  . TRP F 1 116 ? -7.061  -54.081 135.864 1.00 91.95  ? 135 TRP F CA  1 
ATOM   14772 C C   . TRP F 1 116 ? -8.232  -53.127 136.067 1.00 92.74  ? 135 TRP F C   1 
ATOM   14773 O O   . TRP F 1 116 ? -8.318  -52.495 137.124 1.00 91.63  ? 135 TRP F O   1 
ATOM   14774 C CB  . TRP F 1 116 ? -5.929  -53.224 135.292 1.00 90.28  ? 135 TRP F CB  1 
ATOM   14775 C CG  . TRP F 1 116 ? -4.661  -53.900 135.062 1.00 89.42  ? 135 TRP F CG  1 
ATOM   14776 C CD1 . TRP F 1 116 ? -4.258  -55.095 135.567 1.00 89.41  ? 135 TRP F CD1 1 
ATOM   14777 C CD2 . TRP F 1 116 ? -3.593  -53.421 134.252 1.00 88.57  ? 135 TRP F CD2 1 
ATOM   14778 N NE1 . TRP F 1 116 ? -2.990  -55.389 135.129 1.00 88.61  ? 135 TRP F NE1 1 
ATOM   14779 C CE2 . TRP F 1 116 ? -2.562  -54.376 134.311 1.00 88.11  ? 135 TRP F CE2 1 
ATOM   14780 C CE3 . TRP F 1 116 ? -3.408  -52.280 133.478 1.00 88.32  ? 135 TRP F CE3 1 
ATOM   14781 C CZ2 . TRP F 1 116 ? -1.364  -54.222 133.622 1.00 87.46  ? 135 TRP F CZ2 1 
ATOM   14782 C CZ3 . TRP F 1 116 ? -2.223  -52.131 132.796 1.00 87.67  ? 135 TRP F CZ3 1 
ATOM   14783 C CH2 . TRP F 1 116 ? -1.216  -53.095 132.869 1.00 87.27  ? 135 TRP F CH2 1 
ATOM   14784 N N   . TRP F 1 117 ? -9.109  -52.971 135.068 1.00 94.72  ? 136 TRP F N   1 
ATOM   14785 C CA  . TRP F 1 117 ? -10.034 -51.838 135.061 1.00 95.48  ? 136 TRP F CA  1 
ATOM   14786 C C   . TRP F 1 117 ? -10.838 -51.792 136.358 1.00 95.89  ? 136 TRP F C   1 
ATOM   14787 O O   . TRP F 1 117 ? -11.199 -52.823 136.930 1.00 96.71  ? 136 TRP F O   1 
ATOM   14788 C CB  . TRP F 1 117 ? -10.981 -51.885 133.853 1.00 97.87  ? 136 TRP F CB  1 
ATOM   14789 C CG  . TRP F 1 117 ? -10.283 -52.028 132.521 1.00 97.75  ? 136 TRP F CG  1 
ATOM   14790 C CD1 . TRP F 1 117 ? -8.942  -51.954 132.286 1.00 95.83  ? 136 TRP F CD1 1 
ATOM   14791 C CD2 . TRP F 1 117 ? -10.898 -52.304 131.249 1.00 99.82  ? 136 TRP F CD2 1 
ATOM   14792 N NE1 . TRP F 1 117 ? -8.681  -52.158 130.952 1.00 96.63  ? 136 TRP F NE1 1 
ATOM   14793 C CE2 . TRP F 1 117 ? -9.863  -52.384 130.292 1.00 99.03  ? 136 TRP F CE2 1 
ATOM   14794 C CE3 . TRP F 1 117 ? -12.214 -52.497 130.830 1.00 102.41 ? 136 TRP F CE3 1 
ATOM   14795 C CZ2 . TRP F 1 117 ? -10.106 -52.655 128.942 1.00 100.72 ? 136 TRP F CZ2 1 
ATOM   14796 C CZ3 . TRP F 1 117 ? -12.451 -52.757 129.491 1.00 104.04 ? 136 TRP F CZ3 1 
ATOM   14797 C CH2 . TRP F 1 117 ? -11.402 -52.830 128.564 1.00 103.16 ? 136 TRP F CH2 1 
ATOM   14798 N N   . LEU F 1 118 ? -11.074 -50.580 136.844 1.00 95.39  ? 137 LEU F N   1 
ATOM   14799 C CA  . LEU F 1 118 ? -11.822 -50.416 138.083 1.00 95.80  ? 137 LEU F CA  1 
ATOM   14800 C C   . LEU F 1 118 ? -13.286 -50.723 137.805 1.00 98.66  ? 137 LEU F C   1 
ATOM   14801 O O   . LEU F 1 118 ? -13.837 -50.320 136.780 1.00 100.01 ? 137 LEU F O   1 
ATOM   14802 C CB  . LEU F 1 118 ? -11.612 -48.993 138.620 1.00 94.25  ? 137 LEU F CB  1 
ATOM   14803 C CG  . LEU F 1 118 ? -12.124 -48.633 140.008 1.00 94.77  ? 137 LEU F CG  1 
ATOM   14804 C CD1 . LEU F 1 118 ? -11.845 -47.187 140.401 1.00 94.55  ? 137 LEU F CD1 1 
ATOM   14805 C CD2 . LEU F 1 118 ? -13.631 -48.870 140.083 1.00 92.89  ? 137 LEU F CD2 1 
ATOM   14806 N N   . ARG F 1 119 ? -13.907 -51.482 138.705 1.00 99.74  ? 138 ARG F N   1 
ATOM   14807 C CA  . ARG F 1 119 ? -15.353 -51.641 138.723 1.00 102.62 ? 138 ARG F CA  1 
ATOM   14808 C C   . ARG F 1 119 ? -15.935 -51.074 140.011 1.00 102.79 ? 138 ARG F C   1 
ATOM   14809 O O   . ARG F 1 119 ? -15.250 -51.000 141.041 1.00 100.86 ? 138 ARG F O   1 
ATOM   14810 C CB  . ARG F 1 119 ? -15.769 -53.130 138.567 1.00 104.37 ? 138 ARG F CB  1 
ATOM   14811 N N   . THR F 1 120 ? -17.189 -50.639 139.933 1.00 105.31 ? 139 THR F N   1 
ATOM   14812 C CA  . THR F 1 120 ? -17.922 -50.271 141.127 1.00 106.31 ? 139 THR F CA  1 
ATOM   14813 C C   . THR F 1 120 ? -18.555 -51.516 141.749 1.00 107.94 ? 139 THR F C   1 
ATOM   14814 O O   . THR F 1 120 ? -18.628 -52.580 141.124 1.00 108.55 ? 139 THR F O   1 
ATOM   14815 C CB  . THR F 1 120 ? -19.013 -49.243 140.832 1.00 108.56 ? 139 THR F CB  1 
ATOM   14816 O OG1 . THR F 1 120 ? -19.962 -49.291 141.916 1.00 110.31 ? 139 THR F OG1 1 
ATOM   14817 C CG2 . THR F 1 120 ? -19.734 -49.499 139.484 1.00 111.02 ? 139 THR F CG2 1 
ATOM   14818 N N   . THR F 1 121 ? -19.055 -51.360 142.984 1.00 108.96 ? 140 THR F N   1 
ATOM   14819 C CA  . THR F 1 121 ? -19.597 -52.501 143.725 1.00 110.77 ? 140 THR F CA  1 
ATOM   14820 C C   . THR F 1 121 ? -20.573 -53.338 142.889 1.00 113.74 ? 140 THR F C   1 
ATOM   14821 O O   . THR F 1 121 ? -20.741 -54.534 143.137 1.00 114.96 ? 140 THR F O   1 
ATOM   14822 C CB  . THR F 1 121 ? -20.291 -52.028 145.006 1.00 111.90 ? 140 THR F CB  1 
ATOM   14823 O OG1 . THR F 1 121 ? -21.348 -51.117 144.673 1.00 114.09 ? 140 THR F OG1 1 
ATOM   14824 C CG2 . THR F 1 121 ? -19.322 -51.331 145.924 1.00 109.07 ? 140 THR F CG2 1 
ATOM   14825 N N   . THR F 1 122 ? -21.223 -52.738 141.895 1.00 117.04 ? 141 THR F N   1 
ATOM   14826 C CA  . THR F 1 122 ? -22.132 -53.490 141.034 1.00 121.31 ? 141 THR F CA  1 
ATOM   14827 C C   . THR F 1 122 ? -21.420 -54.253 139.925 1.00 120.82 ? 141 THR F C   1 
ATOM   14828 O O   . THR F 1 122 ? -22.062 -55.069 139.249 1.00 124.36 ? 141 THR F O   1 
ATOM   14829 C CB  . THR F 1 122 ? -23.148 -52.532 140.414 1.00 123.81 ? 141 THR F CB  1 
ATOM   14830 O OG1 . THR F 1 122 ? -22.489 -51.720 139.433 1.00 121.53 ? 141 THR F OG1 1 
ATOM   14831 C CG2 . THR F 1 122 ? -23.734 -51.652 141.501 1.00 123.88 ? 141 THR F CG2 1 
ATOM   14832 N N   . GLY F 1 123 ? -20.120 -54.015 139.729 1.00 116.76 ? 142 GLY F N   1 
ATOM   14833 C CA  . GLY F 1 123 ? -19.389 -54.576 138.620 1.00 116.06 ? 142 GLY F CA  1 
ATOM   14834 C C   . GLY F 1 123 ? -19.283 -53.687 137.396 1.00 116.01 ? 142 GLY F C   1 
ATOM   14835 O O   . GLY F 1 123 ? -18.445 -53.951 136.525 1.00 115.04 ? 142 GLY F O   1 
ATOM   14836 N N   . GLU F 1 124 ? -20.115 -52.646 137.300 1.00 117.09 ? 143 GLU F N   1 
ATOM   14837 C CA  . GLU F 1 124 ? -20.011 -51.677 136.220 1.00 117.02 ? 143 GLU F CA  1 
ATOM   14838 C C   . GLU F 1 124 ? -18.703 -50.913 136.331 1.00 112.45 ? 143 GLU F C   1 
ATOM   14839 O O   . GLU F 1 124 ? -18.200 -50.666 137.426 1.00 109.62 ? 143 GLU F O   1 
ATOM   14840 C CB  . GLU F 1 124 ? -21.185 -50.701 136.258 1.00 119.40 ? 143 GLU F CB  1 
ATOM   14841 N N   . LEU F 1 125 ? -18.156 -50.527 135.184 1.00 111.95 ? 144 LEU F N   1 
ATOM   14842 C CA  . LEU F 1 125 ? -16.867 -49.844 135.161 1.00 107.94 ? 144 LEU F CA  1 
ATOM   14843 C C   . LEU F 1 125 ? -16.945 -48.425 135.735 1.00 106.60 ? 144 LEU F C   1 
ATOM   14844 O O   . LEU F 1 125 ? -17.855 -47.658 135.395 1.00 109.02 ? 144 LEU F O   1 
ATOM   14845 C CB  . LEU F 1 125 ? -16.351 -49.782 133.720 1.00 108.08 ? 144 LEU F CB  1 
ATOM   14846 C CG  . LEU F 1 125 ? -15.793 -51.033 133.057 1.00 108.48 ? 144 LEU F CG  1 
ATOM   14847 C CD1 . LEU F 1 125 ? -15.484 -50.752 131.590 1.00 109.37 ? 144 LEU F CD1 1 
ATOM   14848 C CD2 . LEU F 1 125 ? -14.549 -51.496 133.764 1.00 104.70 ? 144 LEU F CD2 1 
ATOM   14849 N N   . ASP F 1 126 ? -15.963 -48.066 136.583 1.00 102.87 ? 145 ASP F N   1 
ATOM   14850 C CA  . ASP F 1 126 ? -15.782 -46.674 137.020 1.00 101.06 ? 145 ASP F CA  1 
ATOM   14851 C C   . ASP F 1 126 ? -15.222 -45.879 135.847 1.00 100.09 ? 145 ASP F C   1 
ATOM   14852 O O   . ASP F 1 126 ? -14.016 -45.879 135.592 1.00 97.32  ? 145 ASP F O   1 
ATOM   14853 C CB  . ASP F 1 126 ? -14.845 -46.536 138.214 1.00 96.52  ? 145 ASP F CB  1 
ATOM   14854 N N   . ARG F 1 127 ? -16.086 -45.213 135.106 1.00 102.35 ? 146 ARG F N   1 
ATOM   14855 C CA  . ARG F 1 127 ? -15.669 -44.377 133.988 1.00 102.21 ? 146 ARG F CA  1 
ATOM   14856 C C   . ARG F 1 127 ? -16.100 -42.939 134.268 1.00 102.57 ? 146 ARG F C   1 
ATOM   14857 O O   . ARG F 1 127 ? -17.240 -42.702 134.684 1.00 104.78 ? 146 ARG F O   1 
ATOM   14858 C CB  . ARG F 1 127 ? -16.262 -44.920 132.684 1.00 105.69 ? 146 ARG F CB  1 
ATOM   14859 N N   . LYS F 1 128 ? -15.178 -41.992 134.081 1.00 100.65 ? 147 LYS F N   1 
ATOM   14860 C CA  . LYS F 1 128 ? -15.559 -40.586 133.983 1.00 101.87 ? 147 LYS F CA  1 
ATOM   14861 C C   . LYS F 1 128 ? -16.388 -40.378 132.716 1.00 105.96 ? 147 LYS F C   1 
ATOM   14862 O O   . LYS F 1 128 ? -16.171 -41.040 131.693 1.00 107.19 ? 147 LYS F O   1 
ATOM   14863 C CB  . LYS F 1 128 ? -14.329 -39.676 133.953 1.00 99.15  ? 147 LYS F CB  1 
ATOM   14864 N N   . LYS F 1 129 ? -17.350 -39.453 132.786 1.00 108.15 ? 148 LYS F N   1 
ATOM   14865 C CA  . LYS F 1 129 ? -18.331 -39.307 131.713 1.00 112.37 ? 148 LYS F CA  1 
ATOM   14866 C C   . LYS F 1 129 ? -18.611 -40.704 131.175 1.00 114.12 ? 148 LYS F C   1 
ATOM   14867 O O   . LYS F 1 129 ? -18.623 -41.678 131.941 1.00 113.52 ? 148 LYS F O   1 
ATOM   14868 C CB  . LYS F 1 129 ? -17.832 -38.368 130.617 1.00 112.62 ? 148 LYS F CB  1 
ATOM   14869 N N   . GLY F 1 130 ? -18.785 -40.826 129.865 1.00 116.28 ? 149 GLY F N   1 
ATOM   14870 C CA  . GLY F 1 130 ? -19.072 -42.117 129.275 1.00 118.53 ? 149 GLY F CA  1 
ATOM   14871 C C   . GLY F 1 130 ? -17.880 -42.637 128.512 1.00 117.17 ? 149 GLY F C   1 
ATOM   14872 O O   . GLY F 1 130 ? -17.998 -43.531 127.672 1.00 119.46 ? 149 GLY F O   1 
ATOM   14873 N N   . GLN F 1 131 ? -16.722 -42.056 128.800 1.00 113.52 ? 150 GLN F N   1 
ATOM   14874 C CA  . GLN F 1 131 ? -15.490 -42.392 128.107 1.00 111.91 ? 150 GLN F CA  1 
ATOM   14875 C C   . GLN F 1 131 ? -14.432 -42.739 129.145 1.00 107.51 ? 150 GLN F C   1 
ATOM   14876 O O   . GLN F 1 131 ? -14.274 -43.916 129.502 1.00 106.77 ? 150 GLN F O   1 
ATOM   14877 C CB  . GLN F 1 131 ? -15.047 -41.228 127.223 1.00 112.50 ? 150 GLN F CB  1 
ATOM   14878 N N   . LEU F 1 132 ? -13.754 -41.709 129.675 1.00 104.82 ? 151 LEU F N   1 
ATOM   14879 C CA  . LEU F 1 132 ? -12.590 -41.850 130.551 1.00 100.66 ? 151 LEU F CA  1 
ATOM   14880 C C   . LEU F 1 132 ? -12.773 -42.803 131.741 1.00 98.75  ? 151 LEU F C   1 
ATOM   14881 O O   . LEU F 1 132 ? -13.440 -42.470 132.726 1.00 98.29  ? 151 LEU F O   1 
ATOM   14882 C CB  . LEU F 1 132 ? -12.181 -40.451 131.063 1.00 98.86  ? 151 LEU F CB  1 
ATOM   14883 N N   . MET F 1 133 ? -12.168 -43.985 131.680 1.00 98.02  ? 152 MET F N   1 
ATOM   14884 C CA  . MET F 1 133 ? -12.190 -44.869 132.843 1.00 96.61  ? 152 MET F CA  1 
ATOM   14885 C C   . MET F 1 133 ? -11.271 -44.308 133.935 1.00 92.84  ? 152 MET F C   1 
ATOM   14886 O O   . MET F 1 133 ? -10.354 -43.524 133.661 1.00 90.98  ? 152 MET F O   1 
ATOM   14887 C CB  . MET F 1 133 ? -11.780 -46.291 132.431 1.00 96.96  ? 152 MET F CB  1 
ATOM   14888 N N   . ARG F 1 134 ? -11.563 -44.662 135.194 1.00 91.99  ? 153 ARG F N   1 
ATOM   14889 C CA  . ARG F 1 134 ? -10.732 -44.280 136.337 1.00 88.59  ? 153 ARG F CA  1 
ATOM   14890 C C   . ARG F 1 134 ? -9.921  -45.490 136.823 1.00 85.13  ? 153 ARG F C   1 
ATOM   14891 O O   . ARG F 1 134 ? -10.357 -46.651 136.727 1.00 86.52  ? 153 ARG F O   1 
ATOM   14892 C CB  . ARG F 1 134 ? -11.567 -43.706 137.497 1.00 87.65  ? 153 ARG F CB  1 
ATOM   14893 C CG  . ARG F 1 134 ? -12.525 -42.586 137.086 1.00 90.81  ? 153 ARG F CG  1 
ATOM   14894 C CD  . ARG F 1 134 ? -13.041 -41.754 138.251 1.00 90.67  ? 153 ARG F CD  1 
ATOM   14895 N NE  . ARG F 1 134 ? -13.752 -42.526 139.257 1.00 89.70  ? 153 ARG F NE  1 
ATOM   14896 C CZ  . ARG F 1 134 ? -14.120 -42.048 140.434 1.00 88.51  ? 153 ARG F CZ  1 
ATOM   14897 N NH1 . ARG F 1 134 ? -13.923 -40.791 140.750 1.00 88.72  ? 153 ARG F NH1 1 
ATOM   14898 N NH2 . ARG F 1 134 ? -14.671 -42.860 141.327 1.00 87.18  ? 153 ARG F NH2 1 
ATOM   14899 N N   . TYR F 1 135 ? -8.723  -45.201 137.353 1.00 81.52  ? 154 TYR F N   1 
ATOM   14900 C CA  . TYR F 1 135 ? -7.731  -46.234 137.610 1.00 79.98  ? 154 TYR F CA  1 
ATOM   14901 C C   . TYR F 1 135 ? -7.950  -46.895 138.974 1.00 79.18  ? 154 TYR F C   1 
ATOM   14902 O O   . TYR F 1 135 ? -8.264  -46.220 139.963 1.00 78.37  ? 154 TYR F O   1 
ATOM   14903 C CB  . TYR F 1 135 ? -6.305  -45.670 137.566 1.00 77.26  ? 154 TYR F CB  1 
ATOM   14904 C CG  . TYR F 1 135 ? -5.771  -45.203 136.230 1.00 78.03  ? 154 TYR F CG  1 
ATOM   14905 C CD1 . TYR F 1 135 ? -5.874  -45.968 135.080 1.00 81.08  ? 154 TYR F CD1 1 
ATOM   14906 C CD2 . TYR F 1 135 ? -5.104  -43.989 136.139 1.00 76.76  ? 154 TYR F CD2 1 
ATOM   14907 C CE1 . TYR F 1 135 ? -5.356  -45.503 133.858 1.00 82.66  ? 154 TYR F CE1 1 
ATOM   14908 C CE2 . TYR F 1 135 ? -4.589  -43.530 134.948 1.00 78.52  ? 154 TYR F CE2 1 
ATOM   14909 C CZ  . TYR F 1 135 ? -4.713  -44.281 133.815 1.00 81.12  ? 154 TYR F CZ  1 
ATOM   14910 O OH  . TYR F 1 135 ? -4.175  -43.791 132.658 1.00 81.91  ? 154 TYR F OH  1 
ATOM   14911 N N   . ASP F 1 136 ? -7.758  -48.219 139.021 1.00 77.88  ? 155 ASP F N   1 
ATOM   14912 C CA  . ASP F 1 136 ? -7.709  -48.944 140.289 1.00 77.18  ? 155 ASP F CA  1 
ATOM   14913 C C   . ASP F 1 136 ? -6.274  -48.864 140.810 1.00 74.13  ? 155 ASP F C   1 
ATOM   14914 O O   . ASP F 1 136 ? -5.430  -49.723 140.536 1.00 73.69  ? 155 ASP F O   1 
ATOM   14915 C CB  . ASP F 1 136 ? -8.182  -50.383 140.132 1.00 79.41  ? 155 ASP F CB  1 
ATOM   14916 C CG  . ASP F 1 136 ? -8.213  -51.127 141.457 1.00 79.11  ? 155 ASP F CG  1 
ATOM   14917 O OD1 . ASP F 1 136 ? -7.928  -50.513 142.494 1.00 77.12  ? 155 ASP F OD1 1 
ATOM   14918 O OD2 . ASP F 1 136 ? -8.511  -52.334 141.471 1.00 80.98  ? 155 ASP F OD2 1 
ATOM   14919 N N   . LEU F 1 137 ? -5.994  -47.804 141.578 1.00 76.00  ? 156 LEU F N   1 
ATOM   14920 C CA  . LEU F 1 137 ? -4.660  -47.628 142.134 1.00 74.25  ? 156 LEU F CA  1 
ATOM   14921 C C   . LEU F 1 137 ? -4.271  -48.785 143.030 1.00 73.97  ? 156 LEU F C   1 
ATOM   14922 O O   . LEU F 1 137 ? -3.097  -48.913 143.390 1.00 72.45  ? 156 LEU F O   1 
ATOM   14923 C CB  . LEU F 1 137 ? -4.572  -46.341 142.948 1.00 74.41  ? 156 LEU F CB  1 
ATOM   14924 C CG  . LEU F 1 137 ? -4.939  -45.035 142.251 1.00 75.34  ? 156 LEU F CG  1 
ATOM   14925 C CD1 . LEU F 1 137 ? -4.652  -43.837 143.142 1.00 74.95  ? 156 LEU F CD1 1 
ATOM   14926 C CD2 . LEU F 1 137 ? -4.168  -44.923 140.968 1.00 74.80  ? 156 LEU F CD2 1 
ATOM   14927 N N   . SER F 1 138 ? -5.242  -49.605 143.429 1.00 73.99  ? 157 SER F N   1 
ATOM   14928 C CA  . SER F 1 138 ? -4.977  -50.745 144.290 1.00 73.86  ? 157 SER F CA  1 
ATOM   14929 C C   . SER F 1 138 ? -4.210  -51.855 143.577 1.00 73.99  ? 157 SER F C   1 
ATOM   14930 O O   . SER F 1 138 ? -3.496  -52.621 144.233 1.00 73.69  ? 157 SER F O   1 
ATOM   14931 C CB  . SER F 1 138 ? -6.308  -51.269 144.828 1.00 76.49  ? 157 SER F CB  1 
ATOM   14932 O OG  . SER F 1 138 ? -6.098  -52.081 145.965 1.00 76.58  ? 157 SER F OG  1 
ATOM   14933 N N   . ASN F 1 139 ? -4.315  -51.947 142.262 1.00 73.86  ? 158 ASN F N   1 
ATOM   14934 C CA  . ASN F 1 139 ? -3.712  -53.050 141.529 1.00 74.82  ? 158 ASN F CA  1 
ATOM   14935 C C   . ASN F 1 139 ? -2.227  -52.802 141.331 1.00 72.61  ? 158 ASN F C   1 
ATOM   14936 O O   . ASN F 1 139 ? -1.849  -51.853 140.655 1.00 71.59  ? 158 ASN F O   1 
ATOM   14937 C CB  . ASN F 1 139 ? -4.432  -53.227 140.191 1.00 76.96  ? 158 ASN F CB  1 
ATOM   14938 C CG  . ASN F 1 139 ? -3.657  -54.117 139.214 1.00 78.51  ? 158 ASN F CG  1 
ATOM   14939 O OD1 . ASN F 1 139 ? -2.434  -54.018 139.078 1.00 77.46  ? 158 ASN F OD1 1 
ATOM   14940 N ND2 . ASN F 1 139 ? -4.358  -54.955 138.518 1.00 81.35  ? 158 ASN F ND2 1 
ATOM   14941 N N   . ALA F 1 140 ? -1.388  -53.686 141.859 1.00 74.71  ? 159 ALA F N   1 
ATOM   14942 C CA  . ALA F 1 140 ? 0.059   -53.514 141.724 1.00 72.40  ? 159 ALA F CA  1 
ATOM   14943 C C   . ALA F 1 140 ? 0.495   -53.559 140.258 1.00 73.08  ? 159 ALA F C   1 
ATOM   14944 O O   . ALA F 1 140 ? 1.338   -52.748 139.825 1.00 71.83  ? 159 ALA F O   1 
ATOM   14945 C CB  . ALA F 1 140 ? 0.802   -54.585 142.545 1.00 72.34  ? 159 ALA F CB  1 
ATOM   14946 N N   . GLU F 1 141 ? -0.054  -54.512 139.486 1.00 73.10  ? 160 GLU F N   1 
ATOM   14947 C CA  . GLU F 1 141 ? 0.267   -54.616 138.059 1.00 74.16  ? 160 GLU F CA  1 
ATOM   14948 C C   . GLU F 1 141 ? -0.005  -53.290 137.342 1.00 73.87  ? 160 GLU F C   1 
ATOM   14949 O O   . GLU F 1 141 ? 0.791   -52.849 136.502 1.00 73.46  ? 160 GLU F O   1 
ATOM   14950 C CB  . GLU F 1 141 ? -0.522  -55.774 137.420 1.00 77.08  ? 160 GLU F CB  1 
ATOM   14951 N N   . PHE F 1 142 ? -1.119  -52.630 137.674 1.00 76.04  ? 161 PHE F N   1 
ATOM   14952 C CA  . PHE F 1 142 ? -1.415  -51.356 137.050 1.00 75.75  ? 161 PHE F CA  1 
ATOM   14953 C C   . PHE F 1 142 ? -0.396  -50.293 137.463 1.00 73.10  ? 161 PHE F C   1 
ATOM   14954 O O   . PHE F 1 142 ? 0.092   -49.522 136.630 1.00 72.91  ? 161 PHE F O   1 
ATOM   14955 C CB  . PHE F 1 142 ? -2.815  -50.882 137.423 1.00 76.84  ? 161 PHE F CB  1 
ATOM   14956 C CG  . PHE F 1 142 ? -2.963  -49.394 137.281 1.00 75.70  ? 161 PHE F CG  1 
ATOM   14957 C CD1 . PHE F 1 142 ? -2.650  -48.768 136.060 1.00 76.53  ? 161 PHE F CD1 1 
ATOM   14958 C CD2 . PHE F 1 142 ? -3.353  -48.616 138.355 1.00 74.41  ? 161 PHE F CD2 1 
ATOM   14959 C CE1 . PHE F 1 142 ? -2.745  -47.404 135.912 1.00 75.77  ? 161 PHE F CE1 1 
ATOM   14960 C CE2 . PHE F 1 142 ? -3.424  -47.219 138.227 1.00 73.64  ? 161 PHE F CE2 1 
ATOM   14961 C CZ  . PHE F 1 142 ? -3.120  -46.611 137.002 1.00 74.35  ? 161 PHE F CZ  1 
ATOM   14962 N N   . ARG F 1 143 ? -0.077  -50.227 138.755 1.00 71.21  ? 162 ARG F N   1 
ATOM   14963 C CA  . ARG F 1 143 ? 0.902   -49.265 139.230 1.00 68.89  ? 162 ARG F CA  1 
ATOM   14964 C C   . ARG F 1 143 ? 2.243   -49.451 138.534 1.00 68.44  ? 162 ARG F C   1 
ATOM   14965 O O   . ARG F 1 143 ? 2.890   -48.467 138.154 1.00 67.54  ? 162 ARG F O   1 
ATOM   14966 C CB  . ARG F 1 143 ? 1.037   -49.386 140.745 1.00 68.29  ? 162 ARG F CB  1 
ATOM   14967 C CG  . ARG F 1 143 ? -0.202  -48.906 141.514 1.00 69.80  ? 162 ARG F CG  1 
ATOM   14968 C CD  . ARG F 1 143 ? 0.121   -48.519 142.979 1.00 69.14  ? 162 ARG F CD  1 
ATOM   14969 N NE  . ARG F 1 143 ? 0.856   -49.552 143.698 1.00 68.38  ? 162 ARG F NE  1 
ATOM   14970 C CZ  . ARG F 1 143 ? 0.299   -50.564 144.360 1.00 68.98  ? 162 ARG F CZ  1 
ATOM   14971 N NH1 . ARG F 1 143 ? -1.015  -50.704 144.446 1.00 71.32  ? 162 ARG F NH1 1 
ATOM   14972 N NH2 . ARG F 1 143 ? 1.085   -51.453 144.959 1.00 69.00  ? 162 ARG F NH2 1 
ATOM   14973 N N   . ASN F 1 144 ? 2.674   -50.700 138.326 1.00 69.05  ? 163 ASN F N   1 
ATOM   14974 C CA  . ASN F 1 144 ? 3.925   -50.889 137.598 1.00 68.97  ? 163 ASN F CA  1 
ATOM   14975 C C   . ASN F 1 144 ? 3.830   -50.323 136.180 1.00 70.33  ? 163 ASN F C   1 
ATOM   14976 O O   . ASN F 1 144 ? 4.773   -49.689 135.687 1.00 69.85  ? 163 ASN F O   1 
ATOM   14977 C CB  . ASN F 1 144 ? 4.318   -52.356 137.558 1.00 70.07  ? 163 ASN F CB  1 
ATOM   14978 C CG  . ASN F 1 144 ? 5.642   -52.568 136.847 1.00 70.34  ? 163 ASN F CG  1 
ATOM   14979 O OD1 . ASN F 1 144 ? 6.689   -52.144 137.320 1.00 68.80  ? 163 ASN F OD1 1 
ATOM   14980 N ND2 . ASN F 1 144 ? 5.594   -53.202 135.687 1.00 72.50  ? 163 ASN F ND2 1 
ATOM   14981 N N   . TRP F 1 145 ? 2.690   -50.522 135.515 1.00 71.41  ? 164 TRP F N   1 
ATOM   14982 C CA  . TRP F 1 145 ? 2.514   -49.993 134.160 1.00 73.23  ? 164 TRP F CA  1 
ATOM   14983 C C   . TRP F 1 145 ? 2.435   -48.464 134.171 1.00 71.98  ? 164 TRP F C   1 
ATOM   14984 O O   . TRP F 1 145 ? 3.183   -47.794 133.449 1.00 72.64  ? 164 TRP F O   1 
ATOM   14985 C CB  . TRP F 1 145 ? 1.270   -50.622 133.514 1.00 76.49  ? 164 TRP F CB  1 
ATOM   14986 C CG  . TRP F 1 145 ? 0.839   -50.006 132.212 1.00 79.95  ? 164 TRP F CG  1 
ATOM   14987 C CD1 . TRP F 1 145 ? 1.233   -50.373 130.955 1.00 81.89  ? 164 TRP F CD1 1 
ATOM   14988 C CD2 . TRP F 1 145 ? -0.089  -48.936 132.042 1.00 80.39  ? 164 TRP F CD2 1 
ATOM   14989 N NE1 . TRP F 1 145 ? 0.599   -49.596 130.004 1.00 83.64  ? 164 TRP F NE1 1 
ATOM   14990 C CE2 . TRP F 1 145 ? -0.212  -48.699 130.649 1.00 82.73  ? 164 TRP F CE2 1 
ATOM   14991 C CE3 . TRP F 1 145 ? -0.836  -48.154 132.926 1.00 78.71  ? 164 TRP F CE3 1 
ATOM   14992 C CZ2 . TRP F 1 145 ? -1.038  -47.703 130.134 1.00 83.96  ? 164 TRP F CZ2 1 
ATOM   14993 C CZ3 . TRP F 1 145 ? -1.650  -47.153 132.407 1.00 80.48  ? 164 TRP F CZ3 1 
ATOM   14994 C CH2 . TRP F 1 145 ? -1.747  -46.943 131.029 1.00 82.80  ? 164 TRP F CH2 1 
ATOM   14995 N N   . TRP F 1 146 ? 1.545   -47.895 134.997 1.00 73.83  ? 165 TRP F N   1 
ATOM   14996 C CA  . TRP F 1 146 ? 1.414   -46.440 135.081 1.00 73.10  ? 165 TRP F CA  1 
ATOM   14997 C C   . TRP F 1 146 ? 2.757   -45.769 135.328 1.00 71.29  ? 165 TRP F C   1 
ATOM   14998 O O   . TRP F 1 146 ? 3.055   -44.718 134.742 1.00 71.59  ? 165 TRP F O   1 
ATOM   14999 C CB  . TRP F 1 146 ? 0.441   -46.066 136.203 1.00 72.44  ? 165 TRP F CB  1 
ATOM   15000 C CG  . TRP F 1 146 ? 0.046   -44.562 136.339 1.00 72.32  ? 165 TRP F CG  1 
ATOM   15001 C CD1 . TRP F 1 146 ? -1.072  -43.976 135.837 1.00 73.64  ? 165 TRP F CD1 1 
ATOM   15002 C CD2 . TRP F 1 146 ? 0.742   -43.523 137.048 1.00 71.50  ? 165 TRP F CD2 1 
ATOM   15003 N NE1 . TRP F 1 146 ? -1.124  -42.660 136.182 1.00 73.27  ? 165 TRP F NE1 1 
ATOM   15004 C CE2 . TRP F 1 146 ? -0.018  -42.352 136.924 1.00 72.10  ? 165 TRP F CE2 1 
ATOM   15005 C CE3 . TRP F 1 146 ? 1.929   -43.474 137.774 1.00 70.67  ? 165 TRP F CE3 1 
ATOM   15006 C CZ2 . TRP F 1 146 ? 0.375   -41.131 137.489 1.00 71.57  ? 165 TRP F CZ2 1 
ATOM   15007 C CZ3 . TRP F 1 146 ? 2.322   -42.263 138.339 1.00 70.12  ? 165 TRP F CZ3 1 
ATOM   15008 C CH2 . TRP F 1 146 ? 1.542   -41.110 138.202 1.00 70.56  ? 165 TRP F CH2 1 
ATOM   15009 N N   . THR F 1 147 ? 3.568   -46.350 136.212 1.00 68.61  ? 166 THR F N   1 
ATOM   15010 C CA  . THR F 1 147 ? 4.869   -45.768 136.521 1.00 67.19  ? 166 THR F CA  1 
ATOM   15011 C C   . THR F 1 147 ? 5.859   -45.997 135.385 1.00 68.18  ? 166 THR F C   1 
ATOM   15012 O O   . THR F 1 147 ? 6.744   -45.164 135.154 1.00 67.82  ? 166 THR F O   1 
ATOM   15013 C CB  . THR F 1 147 ? 5.411   -46.354 137.836 1.00 66.13  ? 166 THR F CB  1 
ATOM   15014 O OG1 . THR F 1 147 ? 5.386   -47.792 137.757 1.00 66.44  ? 166 THR F OG1 1 
ATOM   15015 C CG2 . THR F 1 147 ? 4.562   -45.900 139.043 1.00 66.60  ? 166 THR F CG2 1 
ATOM   15016 N N   . ASN F 1 148 ? 5.719   -47.119 134.663 1.00 66.78  ? 167 ASN F N   1 
ATOM   15017 C CA  . ASN F 1 148 ? 6.575   -47.378 133.505 1.00 69.20  ? 167 ASN F CA  1 
ATOM   15018 C C   . ASN F 1 148 ? 6.373   -46.324 132.429 1.00 71.04  ? 167 ASN F C   1 
ATOM   15019 O O   . ASN F 1 148 ? 7.327   -45.950 131.740 1.00 71.84  ? 167 ASN F O   1 
ATOM   15020 C CB  . ASN F 1 148 ? 6.308   -48.785 132.961 1.00 72.04  ? 167 ASN F CB  1 
ATOM   15021 C CG  . ASN F 1 148 ? 7.040   -49.882 133.764 1.00 70.92  ? 167 ASN F CG  1 
ATOM   15022 O OD1 . ASN F 1 148 ? 7.866   -49.596 134.646 1.00 68.44  ? 167 ASN F OD1 1 
ATOM   15023 N ND2 . ASN F 1 148 ? 6.744   -51.140 133.451 1.00 73.36  ? 167 ASN F ND2 1 
ATOM   15024 N N   . VAL F 1 149 ? 5.156   -45.803 132.296 1.00 72.01  ? 168 VAL F N   1 
ATOM   15025 C CA  . VAL F 1 149 ? 4.934   -44.755 131.310 1.00 74.19  ? 168 VAL F CA  1 
ATOM   15026 C C   . VAL F 1 149 ? 5.651   -43.488 131.725 1.00 71.40  ? 168 VAL F C   1 
ATOM   15027 O O   . VAL F 1 149 ? 6.216   -42.764 130.890 1.00 72.74  ? 168 VAL F O   1 
ATOM   15028 C CB  . VAL F 1 149 ? 3.434   -44.470 131.116 1.00 76.15  ? 168 VAL F CB  1 
ATOM   15029 C CG1 . VAL F 1 149 ? 3.281   -43.274 130.194 1.00 78.16  ? 168 VAL F CG1 1 
ATOM   15030 C CG2 . VAL F 1 149 ? 2.734   -45.716 130.596 1.00 78.68  ? 168 VAL F CG2 1 
ATOM   15031 N N   . ALA F 1 150 ? 5.543   -43.153 133.015 1.00 72.07  ? 169 ALA F N   1 
ATOM   15032 C CA  . ALA F 1 150 ? 6.195   -41.965 133.535 1.00 70.82  ? 169 ALA F CA  1 
ATOM   15033 C C   . ALA F 1 150 ? 7.691   -42.064 133.327 1.00 70.36  ? 169 ALA F C   1 
ATOM   15034 O O   . ALA F 1 150 ? 8.329   -41.107 132.880 1.00 71.17  ? 169 ALA F O   1 
ATOM   15035 C CB  . ALA F 1 150 ? 5.844   -41.789 135.007 1.00 70.27  ? 169 ALA F CB  1 
ATOM   15036 N N   . ALA F 1 151 ? 8.264   -43.235 133.590 1.00 72.52  ? 170 ALA F N   1 
ATOM   15037 C CA  . ALA F 1 151 ? 9.697   -43.406 133.383 1.00 72.38  ? 170 ALA F CA  1 
ATOM   15038 C C   . ALA F 1 151 ? 10.063  -43.271 131.906 1.00 74.74  ? 170 ALA F C   1 
ATOM   15039 O O   . ALA F 1 151 ? 11.042  -42.592 131.572 1.00 75.43  ? 170 ALA F O   1 
ATOM   15040 C CB  . ALA F 1 151 ? 10.144  -44.753 133.949 1.00 71.86  ? 170 ALA F CB  1 
ATOM   15041 N N   . LYS F 1 152 ? 9.293   -43.888 130.999 1.00 72.78  ? 171 LYS F N   1 
ATOM   15042 C CA  . LYS F 1 152 ? 9.528   -43.642 129.576 1.00 75.45  ? 171 LYS F CA  1 
ATOM   15043 C C   . LYS F 1 152 ? 9.711   -42.147 129.341 1.00 75.90  ? 171 LYS F C   1 
ATOM   15044 O O   . LYS F 1 152 ? 10.739  -41.704 128.823 1.00 77.02  ? 171 LYS F O   1 
ATOM   15045 C CB  . LYS F 1 152 ? 8.381   -44.194 128.716 1.00 78.82  ? 171 LYS F CB  1 
ATOM   15046 N N   . ALA F 1 153 ? 8.758   -41.349 129.813 1.00 76.24  ? 172 ALA F N   1 
ATOM   15047 C CA  . ALA F 1 153 ? 8.733   -39.933 129.469 1.00 77.11  ? 172 ALA F CA  1 
ATOM   15048 C C   . ALA F 1 153 ? 9.911   -39.133 130.035 1.00 75.77  ? 172 ALA F C   1 
ATOM   15049 O O   . ALA F 1 153 ? 10.325  -38.147 129.413 1.00 77.23  ? 172 ALA F O   1 
ATOM   15050 C CB  . ALA F 1 153 ? 7.404   -39.334 129.939 1.00 76.63  ? 172 ALA F CB  1 
ATOM   15051 N N   . VAL F 1 154 ? 10.457  -39.496 131.199 1.00 75.02  ? 173 VAL F N   1 
ATOM   15052 C CA  . VAL F 1 154 ? 11.461  -38.656 131.847 1.00 75.30  ? 173 VAL F CA  1 
ATOM   15053 C C   . VAL F 1 154 ? 12.854  -39.272 131.822 1.00 74.82  ? 173 VAL F C   1 
ATOM   15054 O O   . VAL F 1 154 ? 13.846  -38.528 131.844 1.00 75.87  ? 173 VAL F O   1 
ATOM   15055 C CB  . VAL F 1 154 ? 11.060  -38.316 133.298 1.00 74.86  ? 173 VAL F CB  1 
ATOM   15056 C CG1 . VAL F 1 154 ? 9.593   -37.986 133.386 1.00 74.87  ? 173 VAL F CG1 1 
ATOM   15057 C CG2 . VAL F 1 154 ? 11.398  -39.476 134.202 1.00 73.53  ? 173 VAL F CG2 1 
ATOM   15058 N N   . VAL F 1 155 ? 12.961  -40.600 131.822 1.00 75.90  ? 174 VAL F N   1 
ATOM   15059 C CA  . VAL F 1 155 ? 14.248  -41.281 131.763 1.00 76.64  ? 174 VAL F CA  1 
ATOM   15060 C C   . VAL F 1 155 ? 14.650  -41.444 130.306 1.00 79.68  ? 174 VAL F C   1 
ATOM   15061 O O   . VAL F 1 155 ? 15.657  -40.880 129.857 1.00 81.48  ? 174 VAL F O   1 
ATOM   15062 C CB  . VAL F 1 155 ? 14.166  -42.645 132.467 1.00 75.71  ? 174 VAL F CB  1 
ATOM   15063 C CG1 . VAL F 1 155 ? 15.485  -43.375 132.372 1.00 76.62  ? 174 VAL F CG1 1 
ATOM   15064 C CG2 . VAL F 1 155 ? 13.736  -42.443 133.917 1.00 73.07  ? 174 VAL F CG2 1 
ATOM   15065 N N   . ASP F 1 156 ? 13.860  -42.223 129.563 1.00 76.03  ? 175 ASP F N   1 
ATOM   15066 C CA  . ASP F 1 156 ? 14.148  -42.445 128.149 1.00 79.15  ? 175 ASP F CA  1 
ATOM   15067 C C   . ASP F 1 156 ? 13.976  -41.164 127.345 1.00 80.86  ? 175 ASP F C   1 
ATOM   15068 O O   . ASP F 1 156 ? 14.655  -40.968 126.327 1.00 83.51  ? 175 ASP F O   1 
ATOM   15069 C CB  . ASP F 1 156 ? 13.237  -43.532 127.564 1.00 81.30  ? 175 ASP F CB  1 
ATOM   15070 C CG  . ASP F 1 156 ? 13.206  -44.812 128.397 1.00 81.59  ? 175 ASP F CG  1 
ATOM   15071 O OD1 . ASP F 1 156 ? 14.207  -45.134 129.091 1.00 81.57  ? 175 ASP F OD1 1 
ATOM   15072 O OD2 . ASP F 1 156 ? 12.163  -45.500 128.353 1.00 82.49  ? 175 ASP F OD2 1 
ATOM   15073 N N   . GLY F 1 157 ? 13.066  -40.294 127.786 1.00 81.06  ? 176 GLY F N   1 
ATOM   15074 C CA  . GLY F 1 157 ? 12.772  -39.058 127.100 1.00 82.46  ? 176 GLY F CA  1 
ATOM   15075 C C   . GLY F 1 157 ? 13.482  -37.870 127.723 1.00 81.36  ? 176 GLY F C   1 
ATOM   15076 O O   . GLY F 1 157 ? 14.274  -37.988 128.665 1.00 79.83  ? 176 GLY F O   1 
ATOM   15077 N N   . THR F 1 158 ? 13.166  -36.700 127.182 1.00 81.75  ? 177 THR F N   1 
ATOM   15078 C CA  . THR F 1 158 ? 13.881  -35.469 127.471 1.00 81.86  ? 177 THR F CA  1 
ATOM   15079 C C   . THR F 1 158 ? 13.263  -34.670 128.612 1.00 79.54  ? 177 THR F C   1 
ATOM   15080 O O   . THR F 1 158 ? 13.781  -33.600 128.942 1.00 80.27  ? 177 THR F O   1 
ATOM   15081 C CB  . THR F 1 158 ? 13.936  -34.598 126.198 1.00 85.47  ? 177 THR F CB  1 
ATOM   15082 O OG1 . THR F 1 158 ? 14.466  -35.362 125.097 1.00 87.98  ? 177 THR F OG1 1 
ATOM   15083 C CG2 . THR F 1 158 ? 14.806  -33.353 126.410 1.00 86.06  ? 177 THR F CG2 1 
ATOM   15084 N N   . CYS F 1 159 ? 12.185  -35.157 129.222 1.00 78.41  ? 178 CYS F N   1 
ATOM   15085 C CA  . CYS F 1 159 ? 11.528  -34.421 130.292 1.00 76.29  ? 178 CYS F CA  1 
ATOM   15086 C C   . CYS F 1 159 ? 12.309  -34.560 131.602 1.00 74.70  ? 178 CYS F C   1 
ATOM   15087 O O   . CYS F 1 159 ? 13.158  -35.447 131.768 1.00 74.05  ? 178 CYS F O   1 
ATOM   15088 C CB  . CYS F 1 159 ? 10.088  -34.902 130.454 1.00 75.72  ? 178 CYS F CB  1 
ATOM   15089 S SG  . CYS F 1 159 ? 9.020   -34.384 129.087 1.00 78.94  ? 178 CYS F SG  1 
ATOM   15090 N N   . ASP F 1 160 ? 12.019  -33.640 132.528 1.00 70.60  ? 179 ASP F N   1 
ATOM   15091 C CA  . ASP F 1 160 ? 12.681  -33.584 133.825 1.00 68.26  ? 179 ASP F CA  1 
ATOM   15092 C C   . ASP F 1 160 ? 11.830  -34.135 134.963 1.00 65.88  ? 179 ASP F C   1 
ATOM   15093 O O   . ASP F 1 160 ? 12.339  -34.292 136.074 1.00 63.94  ? 179 ASP F O   1 
ATOM   15094 C CB  . ASP F 1 160 ? 13.065  -32.134 134.143 1.00 68.56  ? 179 ASP F CB  1 
ATOM   15095 C CG  . ASP F 1 160 ? 13.932  -31.499 133.055 1.00 71.25  ? 179 ASP F CG  1 
ATOM   15096 O OD1 . ASP F 1 160 ? 15.143  -31.807 133.007 1.00 71.62  ? 179 ASP F OD1 1 
ATOM   15097 O OD2 . ASP F 1 160 ? 13.410  -30.679 132.250 1.00 73.24  ? 179 ASP F OD2 1 
ATOM   15098 N N   . GLY F 1 161 ? 10.558  -34.416 134.722 1.00 63.57  ? 180 GLY F N   1 
ATOM   15099 C CA  . GLY F 1 161 ? 9.693   -34.833 135.812 1.00 61.68  ? 180 GLY F CA  1 
ATOM   15100 C C   . GLY F 1 161 ? 8.273   -35.067 135.355 1.00 62.71  ? 180 GLY F C   1 
ATOM   15101 O O   . GLY F 1 161 ? 7.973   -35.086 134.158 1.00 64.85  ? 180 GLY F O   1 
ATOM   15102 N N   . VAL F 1 162 ? 7.385   -35.227 136.341 1.00 59.97  ? 181 VAL F N   1 
ATOM   15103 C CA  . VAL F 1 162 ? 6.005   -35.633 136.114 1.00 60.87  ? 181 VAL F CA  1 
ATOM   15104 C C   . VAL F 1 162 ? 5.080   -34.753 136.934 1.00 60.39  ? 181 VAL F C   1 
ATOM   15105 O O   . VAL F 1 162 ? 5.340   -34.505 138.116 1.00 58.60  ? 181 VAL F O   1 
ATOM   15106 C CB  . VAL F 1 162 ? 5.732   -37.114 136.508 1.00 60.09  ? 181 VAL F CB  1 
ATOM   15107 C CG1 . VAL F 1 162 ? 4.450   -37.618 135.827 1.00 62.00  ? 181 VAL F CG1 1 
ATOM   15108 C CG2 . VAL F 1 162 ? 6.935   -38.015 136.238 1.00 59.95  ? 181 VAL F CG2 1 
ATOM   15109 N N   . PHE F 1 163 ? 3.975   -34.334 136.323 1.00 61.45  ? 182 PHE F N   1 
ATOM   15110 C CA  . PHE F 1 163 ? 2.876   -33.695 137.036 1.00 62.70  ? 182 PHE F CA  1 
ATOM   15111 C C   . PHE F 1 163 ? 1.810   -34.753 137.243 1.00 63.89  ? 182 PHE F C   1 
ATOM   15112 O O   . PHE F 1 163 ? 1.283   -35.304 136.274 1.00 66.75  ? 182 PHE F O   1 
ATOM   15113 C CB  . PHE F 1 163 ? 2.303   -32.496 136.277 1.00 66.47  ? 182 PHE F CB  1 
ATOM   15114 C CG  . PHE F 1 163 ? 1.234   -31.743 137.041 1.00 67.83  ? 182 PHE F CG  1 
ATOM   15115 C CD1 . PHE F 1 163 ? -0.087  -32.138 136.994 1.00 70.59  ? 182 PHE F CD1 1 
ATOM   15116 C CD2 . PHE F 1 163 ? 1.551   -30.631 137.784 1.00 66.43  ? 182 PHE F CD2 1 
ATOM   15117 C CE1 . PHE F 1 163 ? -1.059  -31.449 137.694 1.00 71.93  ? 182 PHE F CE1 1 
ATOM   15118 C CE2 . PHE F 1 163 ? 0.570   -29.924 138.464 1.00 67.95  ? 182 PHE F CE2 1 
ATOM   15119 C CZ  . PHE F 1 163 ? -0.725  -30.337 138.431 1.00 70.62  ? 182 PHE F CZ  1 
ATOM   15120 N N   . MET F 1 164 ? 1.519   -35.048 138.492 1.00 65.42  ? 183 MET F N   1 
ATOM   15121 C CA  . MET F 1 164 ? 0.601   -36.110 138.892 1.00 65.72  ? 183 MET F CA  1 
ATOM   15122 C C   . MET F 1 164 ? -0.679  -35.431 139.369 1.00 66.64  ? 183 MET F C   1 
ATOM   15123 O O   . MET F 1 164 ? -0.716  -34.868 140.467 1.00 65.61  ? 183 MET F O   1 
ATOM   15124 C CB  . MET F 1 164 ? 1.229   -36.978 139.980 1.00 64.46  ? 183 MET F CB  1 
ATOM   15125 C CG  . MET F 1 164 ? 2.559   -37.581 139.578 1.00 65.44  ? 183 MET F CG  1 
ATOM   15126 S SD  . MET F 1 164 ? 3.210   -38.819 140.758 1.00 64.98  ? 183 MET F SD  1 
ATOM   15127 C CE  . MET F 1 164 ? 1.915   -38.820 141.974 1.00 63.93  ? 183 MET F CE  1 
ATOM   15128 N N   . ASP F 1 165 ? -1.723  -35.501 138.565 1.00 68.35  ? 184 ASP F N   1 
ATOM   15129 C CA  . ASP F 1 165 ? -2.912  -34.727 138.855 1.00 70.81  ? 184 ASP F CA  1 
ATOM   15130 C C   . ASP F 1 165 ? -3.940  -35.557 139.619 1.00 70.89  ? 184 ASP F C   1 
ATOM   15131 O O   . ASP F 1 165 ? -3.815  -36.777 139.776 1.00 69.54  ? 184 ASP F O   1 
ATOM   15132 C CB  . ASP F 1 165 ? -3.514  -34.206 137.546 1.00 74.18  ? 184 ASP F CB  1 
ATOM   15133 C CG  . ASP F 1 165 ? -4.446  -33.047 137.750 1.00 75.72  ? 184 ASP F CG  1 
ATOM   15134 O OD1 . ASP F 1 165 ? -4.861  -32.770 138.888 1.00 74.78  ? 184 ASP F OD1 1 
ATOM   15135 O OD2 . ASP F 1 165 ? -4.757  -32.403 136.745 1.00 78.07  ? 184 ASP F OD2 1 
ATOM   15136 N N   . ALA F 1 166 ? -4.956  -34.850 140.122 1.00 72.51  ? 185 ALA F N   1 
ATOM   15137 C CA  . ALA F 1 166 ? -6.215  -35.409 140.588 1.00 74.00  ? 185 ALA F CA  1 
ATOM   15138 C C   . ALA F 1 166 ? -6.173  -36.136 141.926 1.00 70.98  ? 185 ALA F C   1 
ATOM   15139 O O   . ALA F 1 166 ? -6.939  -37.082 142.119 1.00 71.59  ? 185 ALA F O   1 
ATOM   15140 C CB  . ALA F 1 166 ? -6.776  -36.390 139.530 1.00 76.12  ? 185 ALA F CB  1 
ATOM   15141 N N   . PHE F 1 167 ? -5.331  -35.705 142.867 1.00 69.55  ? 186 PHE F N   1 
ATOM   15142 C CA  . PHE F 1 167 ? -5.352  -36.380 144.166 1.00 68.51  ? 186 PHE F CA  1 
ATOM   15143 C C   . PHE F 1 167 ? -6.636  -36.027 144.925 1.00 70.31  ? 186 PHE F C   1 
ATOM   15144 O O   . PHE F 1 167 ? -7.086  -36.808 145.774 1.00 71.02  ? 186 PHE F O   1 
ATOM   15145 C CB  . PHE F 1 167 ? -4.173  -36.022 145.064 1.00 66.05  ? 186 PHE F CB  1 
ATOM   15146 C CG  . PHE F 1 167 ? -2.861  -36.581 144.624 1.00 64.75  ? 186 PHE F CG  1 
ATOM   15147 C CD1 . PHE F 1 167 ? -2.619  -36.930 143.309 1.00 65.62  ? 186 PHE F CD1 1 
ATOM   15148 C CD2 . PHE F 1 167 ? -1.841  -36.714 145.536 1.00 63.41  ? 186 PHE F CD2 1 
ATOM   15149 C CE1 . PHE F 1 167 ? -1.386  -37.407 142.920 1.00 64.78  ? 186 PHE F CE1 1 
ATOM   15150 C CE2 . PHE F 1 167 ? -0.619  -37.190 145.152 1.00 62.59  ? 186 PHE F CE2 1 
ATOM   15151 C CZ  . PHE F 1 167 ? -0.390  -37.530 143.833 1.00 63.47  ? 186 PHE F CZ  1 
ATOM   15152 N N   . PRO F 1 168 ? -7.239  -34.845 144.704 1.00 71.00  ? 187 PRO F N   1 
ATOM   15153 C CA  . PRO F 1 168 ? -8.528  -34.573 145.346 1.00 73.03  ? 187 PRO F CA  1 
ATOM   15154 C C   . PRO F 1 168 ? -9.658  -35.472 144.842 1.00 75.50  ? 187 PRO F C   1 
ATOM   15155 O O   . PRO F 1 168 ? -10.437 -35.987 145.643 1.00 77.09  ? 187 PRO F O   1 
ATOM   15156 C CB  . PRO F 1 168 ? -8.791  -33.098 145.005 1.00 74.10  ? 187 PRO F CB  1 
ATOM   15157 C CG  . PRO F 1 168 ? -7.418  -32.516 144.847 1.00 71.96  ? 187 PRO F CG  1 
ATOM   15158 C CD  . PRO F 1 168 ? -6.613  -33.611 144.184 1.00 70.62  ? 187 PRO F CD  1 
ATOM   15159 N N   . GLN F 1 169 ? -9.762  -35.647 143.521 1.00 75.33  ? 188 GLN F N   1 
ATOM   15160 C CA  . GLN F 1 169 ? -10.724 -36.587 142.953 1.00 77.86  ? 188 GLN F CA  1 
ATOM   15161 C C   . GLN F 1 169 ? -10.463 -38.035 143.385 1.00 75.34  ? 188 GLN F C   1 
ATOM   15162 O O   . GLN F 1 169 ? -11.325 -38.894 143.180 1.00 76.96  ? 188 GLN F O   1 
ATOM   15163 C CB  . GLN F 1 169 ? -10.699 -36.470 141.427 1.00 81.16  ? 188 GLN F CB  1 
ATOM   15164 N N   . ILE F 1 170 ? -9.319  -38.343 143.978 1.00 75.06  ? 189 ILE F N   1 
ATOM   15165 C CA  . ILE F 1 170 ? -9.111  -39.677 144.510 1.00 75.08  ? 189 ILE F CA  1 
ATOM   15166 C C   . ILE F 1 170 ? -9.609  -39.777 145.948 1.00 76.09  ? 189 ILE F C   1 
ATOM   15167 O O   . ILE F 1 170 ? -10.233 -40.770 146.326 1.00 78.38  ? 189 ILE F O   1 
ATOM   15168 C CB  . ILE F 1 170 ? -7.617  -40.049 144.362 1.00 73.25  ? 189 ILE F CB  1 
ATOM   15169 C CG1 . ILE F 1 170 ? -7.389  -40.659 142.969 1.00 73.23  ? 189 ILE F CG1 1 
ATOM   15170 C CG2 . ILE F 1 170 ? -7.203  -41.026 145.448 1.00 74.09  ? 189 ILE F CG2 1 
ATOM   15171 C CD1 . ILE F 1 170 ? -5.971  -40.619 142.480 1.00 71.65  ? 189 ILE F CD1 1 
ATOM   15172 N N   . ALA F 1 171 ? -9.424  -38.722 146.742 1.00 78.94  ? 190 ALA F N   1 
ATOM   15173 C CA  . ALA F 1 171 ? -9.719  -38.763 148.170 1.00 80.07  ? 190 ALA F CA  1 
ATOM   15174 C C   . ALA F 1 171 ? -11.164 -38.404 148.529 1.00 82.34  ? 190 ALA F C   1 
ATOM   15175 O O   . ALA F 1 171 ? -11.545 -38.538 149.698 1.00 84.00  ? 190 ALA F O   1 
ATOM   15176 C CB  . ALA F 1 171 ? -8.773  -37.820 148.930 1.00 77.62  ? 190 ALA F CB  1 
ATOM   15177 N N   . SER F 1 172 ? -11.974 -37.972 147.568 1.00 81.47  ? 191 SER F N   1 
ATOM   15178 C CA  . SER F 1 172 ? -13.334 -37.534 147.866 1.00 83.77  ? 191 SER F CA  1 
ATOM   15179 C C   . SER F 1 172 ? -14.128 -38.632 148.571 1.00 86.41  ? 191 SER F C   1 
ATOM   15180 O O   . SER F 1 172 ? -14.313 -39.729 148.022 1.00 86.94  ? 191 SER F O   1 
ATOM   15181 C CB  . SER F 1 172 ? -14.018 -37.138 146.570 1.00 86.43  ? 191 SER F CB  1 
ATOM   15182 O OG  . SER F 1 172 ? -13.474 -37.921 145.521 1.00 86.65  ? 191 SER F OG  1 
ATOM   15183 N N   . GLN F 1 173 ? -14.624 -38.320 149.778 1.00 84.80  ? 192 GLN F N   1 
ATOM   15184 C CA  . GLN F 1 173 ? -15.340 -39.312 150.574 1.00 87.12  ? 192 GLN F CA  1 
ATOM   15185 C C   . GLN F 1 173 ? -16.436 -39.979 149.763 1.00 89.96  ? 192 GLN F C   1 
ATOM   15186 O O   . GLN F 1 173 ? -16.784 -41.133 150.027 1.00 91.39  ? 192 GLN F O   1 
ATOM   15187 C CB  . GLN F 1 173 ? -15.926 -38.669 151.835 1.00 88.54  ? 192 GLN F CB  1 
ATOM   15188 N N   . ALA F 1 174 ? -16.943 -39.296 148.731 1.00 86.84  ? 193 ALA F N   1 
ATOM   15189 C CA  . ALA F 1 174 ? -18.056 -39.823 147.942 1.00 90.19  ? 193 ALA F CA  1 
ATOM   15190 C C   . ALA F 1 174 ? -17.694 -41.089 147.172 1.00 89.67  ? 193 ALA F C   1 
ATOM   15191 O O   . ALA F 1 174 ? -18.585 -41.877 146.827 1.00 92.60  ? 193 ALA F O   1 
ATOM   15192 C CB  . ALA F 1 174 ? -18.544 -38.759 146.958 1.00 93.18  ? 193 ALA F CB  1 
ATOM   15193 N N   . ASN F 1 175 ? -16.416 -41.289 146.847 1.00 90.67  ? 194 ASN F N   1 
ATOM   15194 C CA  . ASN F 1 175 ? -16.024 -42.523 146.172 1.00 90.18  ? 194 ASN F CA  1 
ATOM   15195 C C   . ASN F 1 175 ? -16.307 -43.750 147.023 1.00 91.31  ? 194 ASN F C   1 
ATOM   15196 O O   . ASN F 1 175 ? -16.428 -44.856 146.481 1.00 92.51  ? 194 ASN F O   1 
ATOM   15197 C CB  . ASN F 1 175 ? -14.540 -42.486 145.815 1.00 86.73  ? 194 ASN F CB  1 
ATOM   15198 C CG  . ASN F 1 175 ? -14.257 -41.519 144.701 1.00 86.09  ? 194 ASN F CG  1 
ATOM   15199 O OD1 . ASN F 1 175 ? -15.177 -40.925 144.182 1.00 88.41  ? 194 ASN F OD1 1 
ATOM   15200 N ND2 . ASN F 1 175 ? -12.994 -41.337 144.340 1.00 83.46  ? 194 ASN F ND2 1 
ATOM   15201 N N   . ARG F 1 176 ? -16.402 -43.583 148.345 1.00 90.41  ? 195 ARG F N   1 
ATOM   15202 C CA  . ARG F 1 176 ? -16.806 -44.693 149.199 1.00 91.89  ? 195 ARG F CA  1 
ATOM   15203 C C   . ARG F 1 176 ? -18.128 -45.304 148.715 1.00 96.07  ? 195 ARG F C   1 
ATOM   15204 O O   . ARG F 1 176 ? -18.297 -46.529 148.768 1.00 97.39  ? 195 ARG F O   1 
ATOM   15205 C CB  . ARG F 1 176 ? -16.879 -44.214 150.661 1.00 92.05  ? 195 ARG F CB  1 
ATOM   15206 C CG  . ARG F 1 176 ? -15.503 -43.938 151.316 1.00 90.31  ? 195 ARG F CG  1 
ATOM   15207 C CD  . ARG F 1 176 ? -15.584 -43.533 152.807 1.00 91.90  ? 195 ARG F CD  1 
ATOM   15208 N NE  . ARG F 1 176 ? -14.270 -43.348 153.435 1.00 90.72  ? 195 ARG F NE  1 
ATOM   15209 C CZ  . ARG F 1 176 ? -13.529 -44.307 153.995 1.00 90.51  ? 195 ARG F CZ  1 
ATOM   15210 N NH1 . ARG F 1 176 ? -13.925 -45.578 154.024 1.00 91.30  ? 195 ARG F NH1 1 
ATOM   15211 N NH2 . ARG F 1 176 ? -12.359 -43.983 154.543 1.00 89.01  ? 195 ARG F NH2 1 
ATOM   15212 N N   . LYS F 1 177 ? -19.044 -44.483 148.173 1.00 93.50  ? 196 LYS F N   1 
ATOM   15213 C CA  . LYS F 1 177 ? -20.356 -44.997 147.765 1.00 98.24  ? 196 LYS F CA  1 
ATOM   15214 C C   . LYS F 1 177 ? -20.258 -45.909 146.544 1.00 99.63  ? 196 LYS F C   1 
ATOM   15215 O O   . LYS F 1 177 ? -21.009 -46.892 146.426 1.00 103.53 ? 196 LYS F O   1 
ATOM   15216 C CB  . LYS F 1 177 ? -21.320 -43.847 147.472 1.00 101.94 ? 196 LYS F CB  1 
ATOM   15217 N N   . LEU F 1 178 ? -19.347 -45.602 145.620 1.00 99.15  ? 197 LEU F N   1 
ATOM   15218 C CA  . LEU F 1 178 ? -19.198 -46.450 144.443 1.00 99.78  ? 197 LEU F CA  1 
ATOM   15219 C C   . LEU F 1 178 ? -18.411 -47.724 144.736 1.00 98.49  ? 197 LEU F C   1 
ATOM   15220 O O   . LEU F 1 178 ? -18.725 -48.782 144.180 1.00 100.57 ? 197 LEU F O   1 
ATOM   15221 C CB  . LEU F 1 178 ? -18.502 -45.670 143.333 1.00 97.59  ? 197 LEU F CB  1 
ATOM   15222 C CG  . LEU F 1 178 ? -18.727 -44.162 143.320 1.00 98.07  ? 197 LEU F CG  1 
ATOM   15223 C CD1 . LEU F 1 178 ? -17.782 -43.600 142.268 1.00 97.84  ? 197 LEU F CD1 1 
ATOM   15224 C CD2 . LEU F 1 178 ? -20.201 -43.831 143.039 1.00 104.17 ? 197 LEU F CD2 1 
ATOM   15225 N N   . TRP F 1 179 ? -17.390 -47.634 145.598 1.00 96.93  ? 198 TRP F N   1 
ATOM   15226 C CA  . TRP F 1 179 ? -16.404 -48.692 145.780 1.00 95.24  ? 198 TRP F CA  1 
ATOM   15227 C C   . TRP F 1 179 ? -16.575 -49.503 147.054 1.00 96.21  ? 198 TRP F C   1 
ATOM   15228 O O   . TRP F 1 179 ? -15.971 -50.574 147.172 1.00 96.07  ? 198 TRP F O   1 
ATOM   15229 C CB  . TRP F 1 179 ? -14.987 -48.102 145.833 1.00 90.99  ? 198 TRP F CB  1 
ATOM   15230 C CG  . TRP F 1 179 ? -14.554 -47.369 144.613 1.00 89.82  ? 198 TRP F CG  1 
ATOM   15231 C CD1 . TRP F 1 179 ? -14.994 -47.566 143.344 1.00 91.79  ? 198 TRP F CD1 1 
ATOM   15232 C CD2 . TRP F 1 179 ? -13.574 -46.332 144.542 1.00 86.69  ? 198 TRP F CD2 1 
ATOM   15233 N NE1 . TRP F 1 179 ? -14.355 -46.713 142.488 1.00 90.11  ? 198 TRP F NE1 1 
ATOM   15234 C CE2 . TRP F 1 179 ? -13.475 -45.946 143.198 1.00 87.00  ? 198 TRP F CE2 1 
ATOM   15235 C CE3 . TRP F 1 179 ? -12.767 -45.691 145.489 1.00 84.57  ? 198 TRP F CE3 1 
ATOM   15236 C CZ2 . TRP F 1 179 ? -12.604 -44.952 142.768 1.00 84.67  ? 198 TRP F CZ2 1 
ATOM   15237 C CZ3 . TRP F 1 179 ? -11.895 -44.696 145.061 1.00 82.73  ? 198 TRP F CZ3 1 
ATOM   15238 C CH2 . TRP F 1 179 ? -11.820 -44.344 143.713 1.00 82.15  ? 198 TRP F CH2 1 
ATOM   15239 N N   . GLY F 1 180 ? -17.341 -49.009 148.017 1.00 95.16  ? 199 GLY F N   1 
ATOM   15240 C CA  . GLY F 1 180 ? -17.311 -49.601 149.335 1.00 95.48  ? 199 GLY F CA  1 
ATOM   15241 C C   . GLY F 1 180 ? -16.051 -49.212 150.065 1.00 91.62  ? 199 GLY F C   1 
ATOM   15242 O O   . GLY F 1 180 ? -15.047 -48.838 149.429 1.00 88.59  ? 199 GLY F O   1 
ATOM   15243 N N   . ASP F 1 181 ? -16.073 -49.295 151.390 1.00 94.80  ? 200 ASP F N   1 
ATOM   15244 C CA  . ASP F 1 181 ? -14.977 -48.749 152.179 1.00 91.77  ? 200 ASP F CA  1 
ATOM   15245 C C   . ASP F 1 181 ? -13.683 -49.526 151.941 1.00 88.95  ? 200 ASP F C   1 
ATOM   15246 O O   . ASP F 1 181 ? -12.638 -48.917 151.683 1.00 85.69  ? 200 ASP F O   1 
ATOM   15247 C CB  . ASP F 1 181 ? -15.368 -48.729 153.661 1.00 95.18  ? 200 ASP F CB  1 
ATOM   15248 C CG  . ASP F 1 181 ? -16.404 -47.647 153.976 1.00 99.08  ? 200 ASP F CG  1 
ATOM   15249 O OD1 . ASP F 1 181 ? -16.373 -46.608 153.295 1.00 97.96  ? 200 ASP F OD1 1 
ATOM   15250 O OD2 . ASP F 1 181 ? -17.244 -47.829 154.887 1.00 103.52 ? 200 ASP F OD2 1 
ATOM   15251 N N   . GLU F 1 182 ? -13.739 -50.866 151.971 1.00 90.11  ? 201 GLU F N   1 
ATOM   15252 C CA  . GLU F 1 182 ? -12.538 -51.666 151.738 1.00 87.52  ? 201 GLU F CA  1 
ATOM   15253 C C   . GLU F 1 182 ? -11.784 -51.165 150.505 1.00 84.31  ? 201 GLU F C   1 
ATOM   15254 O O   . GLU F 1 182 ? -10.647 -50.697 150.607 1.00 81.24  ? 201 GLU F O   1 
ATOM   15255 C CB  . GLU F 1 182 ? -12.898 -53.151 151.612 1.00 90.19  ? 201 GLU F CB  1 
ATOM   15256 N N   . LYS F 1 183 ? -12.417 -51.199 149.332 1.00 84.78  ? 202 LYS F N   1 
ATOM   15257 C CA  . LYS F 1 183 ? -11.718 -50.772 148.119 1.00 82.78  ? 202 LYS F CA  1 
ATOM   15258 C C   . LYS F 1 183 ? -11.237 -49.320 148.208 1.00 80.25  ? 202 LYS F C   1 
ATOM   15259 O O   . LYS F 1 183 ? -10.205 -48.974 147.621 1.00 77.63  ? 202 LYS F O   1 
ATOM   15260 C CB  . LYS F 1 183 ? -12.636 -50.990 146.911 1.00 85.36  ? 202 LYS F CB  1 
ATOM   15261 C CG  . LYS F 1 183 ? -12.129 -50.444 145.589 1.00 83.97  ? 202 LYS F CG  1 
ATOM   15262 C CD  . LYS F 1 183 ? -10.805 -51.056 145.170 1.00 81.91  ? 202 LYS F CD  1 
ATOM   15263 C CE  . LYS F 1 183 ? -10.980 -52.191 144.187 1.00 83.97  ? 202 LYS F CE  1 
ATOM   15264 N NZ  . LYS F 1 183 ? -9.656  -52.827 143.935 1.00 81.92  ? 202 LYS F NZ  1 
ATOM   15265 N N   . PHE F 1 184 ? -11.941 -48.468 148.951 1.00 84.50  ? 203 PHE F N   1 
ATOM   15266 C CA  . PHE F 1 184 ? -11.553 -47.065 149.037 1.00 82.86  ? 203 PHE F CA  1 
ATOM   15267 C C   . PHE F 1 184 ? -10.282 -46.889 149.860 1.00 80.62  ? 203 PHE F C   1 
ATOM   15268 O O   . PHE F 1 184 ? -9.365  -46.141 149.464 1.00 77.66  ? 203 PHE F O   1 
ATOM   15269 C CB  . PHE F 1 184 ? -12.700 -46.266 149.642 1.00 86.31  ? 203 PHE F CB  1 
ATOM   15270 C CG  . PHE F 1 184 ? -12.423 -44.792 149.782 1.00 84.80  ? 203 PHE F CG  1 
ATOM   15271 C CD1 . PHE F 1 184 ? -12.773 -43.903 148.771 1.00 83.76  ? 203 PHE F CD1 1 
ATOM   15272 C CD2 . PHE F 1 184 ? -11.848 -44.287 150.949 1.00 85.43  ? 203 PHE F CD2 1 
ATOM   15273 C CE1 . PHE F 1 184 ? -12.535 -42.531 148.913 1.00 83.06  ? 203 PHE F CE1 1 
ATOM   15274 C CE2 . PHE F 1 184 ? -11.609 -42.925 151.104 1.00 84.70  ? 203 PHE F CE2 1 
ATOM   15275 C CZ  . PHE F 1 184 ? -11.948 -42.043 150.089 1.00 83.49  ? 203 PHE F CZ  1 
ATOM   15276 N N   . GLU F 1 185 ? -10.235 -47.535 151.037 1.00 80.58  ? 204 GLU F N   1 
ATOM   15277 C CA  . GLU F 1 185 ? -9.005  -47.571 151.826 1.00 78.89  ? 204 GLU F CA  1 
ATOM   15278 C C   . GLU F 1 185 ? -7.823  -47.994 150.963 1.00 74.78  ? 204 GLU F C   1 
ATOM   15279 O O   . GLU F 1 185 ? -6.713  -47.462 151.095 1.00 72.32  ? 204 GLU F O   1 
ATOM   15280 C CB  . GLU F 1 185 ? -9.103  -48.580 152.987 1.00 81.92  ? 204 GLU F CB  1 
ATOM   15281 C CG  . GLU F 1 185 ? -10.411 -48.673 153.774 1.00 86.94  ? 204 GLU F CG  1 
ATOM   15282 C CD  . GLU F 1 185 ? -10.543 -47.575 154.806 1.00 88.38  ? 204 GLU F CD  1 
ATOM   15283 O OE1 . GLU F 1 185 ? -11.256 -47.810 155.808 1.00 90.76  ? 204 GLU F OE1 1 
ATOM   15284 O OE2 . GLU F 1 185 ? -9.953  -46.486 154.612 1.00 87.73  ? 204 GLU F OE2 1 
ATOM   15285 N N   . ALA F 1 186 ? -8.044  -48.997 150.106 1.00 78.71  ? 205 ALA F N   1 
ATOM   15286 C CA  . ALA F 1 186 ? -6.956  -49.613 149.361 1.00 75.95  ? 205 ALA F CA  1 
ATOM   15287 C C   . ALA F 1 186 ? -6.460  -48.681 148.280 1.00 73.62  ? 205 ALA F C   1 
ATOM   15288 O O   . ALA F 1 186 ? -5.254  -48.587 148.027 1.00 71.06  ? 205 ALA F O   1 
ATOM   15289 C CB  . ALA F 1 186 ? -7.423  -50.940 148.758 1.00 77.28  ? 205 ALA F CB  1 
ATOM   15290 N N   . ILE F 1 187 ? -7.383  -47.972 147.647 1.00 75.77  ? 206 ILE F N   1 
ATOM   15291 C CA  . ILE F 1 187 ? -7.010  -46.998 146.634 1.00 73.62  ? 206 ILE F CA  1 
ATOM   15292 C C   . ILE F 1 187 ? -6.283  -45.824 147.271 1.00 71.95  ? 206 ILE F C   1 
ATOM   15293 O O   . ILE F 1 187 ? -5.281  -45.330 146.734 1.00 69.39  ? 206 ILE F O   1 
ATOM   15294 C CB  . ILE F 1 187 ? -8.263  -46.598 145.826 1.00 75.77  ? 206 ILE F CB  1 
ATOM   15295 C CG1 . ILE F 1 187 ? -8.606  -47.813 144.930 1.00 77.05  ? 206 ILE F CG1 1 
ATOM   15296 C CG2 . ILE F 1 187 ? -8.055  -45.305 145.046 1.00 74.16  ? 206 ILE F CG2 1 
ATOM   15297 C CD1 . ILE F 1 187 ? -9.843  -47.684 144.107 1.00 79.81  ? 206 ILE F CD1 1 
ATOM   15298 N N   . GLN F 1 188 ? -6.705  -45.411 148.469 1.00 72.34  ? 207 GLN F N   1 
ATOM   15299 C CA  . GLN F 1 188 ? -5.936  -44.365 149.150 1.00 71.20  ? 207 GLN F CA  1 
ATOM   15300 C C   . GLN F 1 188 ? -4.510  -44.833 149.451 1.00 68.83  ? 207 GLN F C   1 
ATOM   15301 O O   . GLN F 1 188 ? -3.560  -44.049 149.333 1.00 66.56  ? 207 GLN F O   1 
ATOM   15302 C CB  . GLN F 1 188 ? -6.613  -43.922 150.446 1.00 74.23  ? 207 GLN F CB  1 
ATOM   15303 C CG  . GLN F 1 188 ? -8.026  -43.346 150.291 1.00 76.81  ? 207 GLN F CG  1 
ATOM   15304 C CD  . GLN F 1 188 ? -8.154  -42.336 149.181 1.00 75.80  ? 207 GLN F CD  1 
ATOM   15305 O OE1 . GLN F 1 188 ? -7.990  -41.139 149.394 1.00 75.86  ? 207 GLN F OE1 1 
ATOM   15306 N NE2 . GLN F 1 188 ? -8.464  -42.816 147.979 1.00 75.16  ? 207 GLN F NE2 1 
ATOM   15307 N N   . GLN F 1 189 ? -4.338  -46.107 149.855 1.00 67.79  ? 208 GLN F N   1 
ATOM   15308 C CA  . GLN F 1 189 ? -2.987  -46.621 150.075 1.00 65.38  ? 208 GLN F CA  1 
ATOM   15309 C C   . GLN F 1 189 ? -2.244  -46.827 148.764 1.00 64.20  ? 208 GLN F C   1 
ATOM   15310 O O   . GLN F 1 189 ? -1.017  -46.705 148.720 1.00 62.41  ? 208 GLN F O   1 
ATOM   15311 C CB  . GLN F 1 189 ? -3.008  -47.936 150.833 1.00 66.32  ? 208 GLN F CB  1 
ATOM   15312 C CG  . GLN F 1 189 ? -1.601  -48.502 151.069 1.00 64.49  ? 208 GLN F CG  1 
ATOM   15313 C CD  . GLN F 1 189 ? -0.740  -47.588 151.931 1.00 63.66  ? 208 GLN F CD  1 
ATOM   15314 O OE1 . GLN F 1 189 ? -1.221  -47.056 152.932 1.00 66.39  ? 208 GLN F OE1 1 
ATOM   15315 N NE2 . GLN F 1 189 ? 0.534   -47.409 151.556 1.00 61.15  ? 208 GLN F NE2 1 
ATOM   15316 N N   . GLY F 1 190 ? -2.963  -47.172 147.701 1.00 65.61  ? 209 GLY F N   1 
ATOM   15317 C CA  . GLY F 1 190 ? -2.341  -47.254 146.393 1.00 65.29  ? 209 GLY F CA  1 
ATOM   15318 C C   . GLY F 1 190 ? -1.780  -45.932 145.901 1.00 63.89  ? 209 GLY F C   1 
ATOM   15319 O O   . GLY F 1 190 ? -0.779  -45.916 145.183 1.00 62.99  ? 209 GLY F O   1 
ATOM   15320 N N   . LEU F 1 191 ? -2.421  -44.810 146.248 1.00 64.40  ? 210 LEU F N   1 
ATOM   15321 C CA  . LEU F 1 191 ? -1.889  -43.511 145.830 1.00 63.03  ? 210 LEU F CA  1 
ATOM   15322 C C   . LEU F 1 191 ? -0.555  -43.223 146.522 1.00 60.90  ? 210 LEU F C   1 
ATOM   15323 O O   . LEU F 1 191 ? 0.421   -42.835 145.869 1.00 59.84  ? 210 LEU F O   1 
ATOM   15324 C CB  . LEU F 1 191 ? -2.913  -42.415 146.107 1.00 64.70  ? 210 LEU F CB  1 
ATOM   15325 C CG  . LEU F 1 191 ? -2.524  -40.993 145.727 1.00 63.84  ? 210 LEU F CG  1 
ATOM   15326 C CD1 . LEU F 1 191 ? -2.270  -40.762 144.240 1.00 63.37  ? 210 LEU F CD1 1 
ATOM   15327 C CD2 . LEU F 1 191 ? -3.609  -40.016 146.200 1.00 66.55  ? 210 LEU F CD2 1 
ATOM   15328 N N   . GLN F 1 192 ? -0.485  -43.433 147.842 1.00 62.52  ? 211 GLN F N   1 
ATOM   15329 C CA  . GLN F 1 192 ? 0.800   -43.382 148.528 1.00 60.98  ? 211 GLN F CA  1 
ATOM   15330 C C   . GLN F 1 192 ? 1.831   -44.256 147.818 1.00 59.20  ? 211 GLN F C   1 
ATOM   15331 O O   . GLN F 1 192 ? 2.936   -43.815 147.491 1.00 57.69  ? 211 GLN F O   1 
ATOM   15332 C CB  . GLN F 1 192 ? 0.647   -43.868 149.973 1.00 62.29  ? 211 GLN F CB  1 
ATOM   15333 C CG  . GLN F 1 192 ? -0.014  -42.901 150.927 1.00 64.49  ? 211 GLN F CG  1 
ATOM   15334 C CD  . GLN F 1 192 ? 0.997   -42.204 151.820 1.00 63.60  ? 211 GLN F CD  1 
ATOM   15335 O OE1 . GLN F 1 192 ? 1.765   -42.854 152.550 1.00 63.27  ? 211 GLN F OE1 1 
ATOM   15336 N NE2 . GLN F 1 192 ? 1.013   -40.852 151.755 1.00 64.17  ? 211 GLN F NE2 1 
ATOM   15337 N N   . ASP F 1 193 ? 1.475   -45.520 147.594 1.00 59.71  ? 212 ASP F N   1 
ATOM   15338 C CA  . ASP F 1 193 ? 2.390   -46.487 147.008 1.00 59.68  ? 212 ASP F CA  1 
ATOM   15339 C C   . ASP F 1 193 ? 2.819   -46.100 145.591 1.00 59.71  ? 212 ASP F C   1 
ATOM   15340 O O   . ASP F 1 193 ? 3.947   -46.408 145.181 1.00 59.12  ? 212 ASP F O   1 
ATOM   15341 C CB  . ASP F 1 193 ? 1.717   -47.873 147.031 1.00 61.45  ? 212 ASP F CB  1 
ATOM   15342 C CG  . ASP F 1 193 ? 1.633   -48.495 148.457 1.00 62.78  ? 212 ASP F CG  1 
ATOM   15343 O OD1 . ASP F 1 193 ? 2.456   -48.108 149.341 1.00 65.93  ? 212 ASP F OD1 1 
ATOM   15344 O OD2 . ASP F 1 193 ? 0.764   -49.394 148.690 1.00 61.78  ? 212 ASP F OD2 1 
ATOM   15345 N N   . ILE F 1 194 ? 1.951   -45.428 144.825 1.00 59.11  ? 213 ILE F N   1 
ATOM   15346 C CA  . ILE F 1 194 ? 2.271   -45.179 143.415 1.00 59.57  ? 213 ILE F CA  1 
ATOM   15347 C C   . ILE F 1 194 ? 3.263   -44.034 143.312 1.00 58.13  ? 213 ILE F C   1 
ATOM   15348 O O   . ILE F 1 194 ? 4.139   -44.031 142.434 1.00 58.09  ? 213 ILE F O   1 
ATOM   15349 C CB  . ILE F 1 194 ? 0.990   -44.936 142.590 1.00 61.35  ? 213 ILE F CB  1 
ATOM   15350 C CG1 . ILE F 1 194 ? 1.179   -45.406 141.138 1.00 62.67  ? 213 ILE F CG1 1 
ATOM   15351 C CG2 . ILE F 1 194 ? 0.566   -43.469 142.602 1.00 61.01  ? 213 ILE F CG2 1 
ATOM   15352 C CD1 . ILE F 1 194 ? -0.124  -45.292 140.282 1.00 64.86  ? 213 ILE F CD1 1 
ATOM   15353 N N   . ILE F 1 195 ? 3.190   -43.079 144.232 1.00 57.43  ? 214 ILE F N   1 
ATOM   15354 C CA  . ILE F 1 195 ? 4.184   -42.009 144.244 1.00 56.19  ? 214 ILE F CA  1 
ATOM   15355 C C   . ILE F 1 195 ? 5.564   -42.582 144.524 1.00 55.17  ? 214 ILE F C   1 
ATOM   15356 O O   . ILE F 1 195 ? 6.551   -42.257 143.854 1.00 54.95  ? 214 ILE F O   1 
ATOM   15357 C CB  . ILE F 1 195 ? 3.823   -40.925 145.266 1.00 55.45  ? 214 ILE F CB  1 
ATOM   15358 C CG1 . ILE F 1 195 ? 2.440   -40.369 145.008 1.00 56.63  ? 214 ILE F CG1 1 
ATOM   15359 C CG2 . ILE F 1 195 ? 4.774   -39.811 145.150 1.00 54.41  ? 214 ILE F CG2 1 
ATOM   15360 C CD1 . ILE F 1 195 ? 1.834   -39.797 146.193 1.00 56.27  ? 214 ILE F CD1 1 
ATOM   15361 N N   . GLN F 1 196 ? 5.644   -43.450 145.537 1.00 57.20  ? 215 GLN F N   1 
ATOM   15362 C CA  . GLN F 1 196 ? 6.894   -44.129 145.849 1.00 56.54  ? 215 GLN F CA  1 
ATOM   15363 C C   . GLN F 1 196 ? 7.468   -44.852 144.633 1.00 57.81  ? 215 GLN F C   1 
ATOM   15364 O O   . GLN F 1 196 ? 8.613   -44.602 144.248 1.00 57.71  ? 215 GLN F O   1 
ATOM   15365 C CB  . GLN F 1 196 ? 6.668   -45.105 146.992 1.00 56.60  ? 215 GLN F CB  1 
ATOM   15366 C CG  . GLN F 1 196 ? 7.919   -45.752 147.453 1.00 56.47  ? 215 GLN F CG  1 
ATOM   15367 C CD  . GLN F 1 196 ? 7.717   -46.593 148.658 1.00 56.69  ? 215 GLN F CD  1 
ATOM   15368 O OE1 . GLN F 1 196 ? 6.581   -46.909 149.054 1.00 57.42  ? 215 GLN F OE1 1 
ATOM   15369 N NE2 . GLN F 1 196 ? 8.817   -46.981 149.256 1.00 56.31  ? 215 GLN F NE2 1 
ATOM   15370 N N   . GLU F 1 197 ? 6.666   -45.715 143.980 1.00 58.02  ? 216 GLU F N   1 
ATOM   15371 C CA  . GLU F 1 197 ? 7.140   -46.413 142.786 1.00 59.09  ? 216 GLU F CA  1 
ATOM   15372 C C   . GLU F 1 197 ? 7.542   -45.438 141.683 1.00 59.37  ? 216 GLU F C   1 
ATOM   15373 O O   . GLU F 1 197 ? 8.495   -45.679 140.941 1.00 59.84  ? 216 GLU F O   1 
ATOM   15374 C CB  . GLU F 1 197 ? 6.072   -47.370 142.262 1.00 60.78  ? 216 GLU F CB  1 
ATOM   15375 C CG  . GLU F 1 197 ? 5.733   -48.548 143.154 1.00 61.44  ? 216 GLU F CG  1 
ATOM   15376 C CD  . GLU F 1 197 ? 4.446   -49.274 142.692 1.00 64.43  ? 216 GLU F CD  1 
ATOM   15377 O OE1 . GLU F 1 197 ? 4.235   -49.460 141.462 1.00 67.58  ? 216 GLU F OE1 1 
ATOM   15378 O OE2 . GLU F 1 197 ? 3.652   -49.651 143.596 1.00 64.78  ? 216 GLU F OE2 1 
ATOM   15379 N N   . THR F 1 198 ? 6.797   -44.361 141.511 1.00 56.86  ? 217 THR F N   1 
ATOM   15380 C CA  . THR F 1 198 ? 7.222   -43.370 140.518 1.00 57.28  ? 217 THR F CA  1 
ATOM   15381 C C   . THR F 1 198 ? 8.647   -42.901 140.795 1.00 56.24  ? 217 THR F C   1 
ATOM   15382 O O   . THR F 1 198 ? 9.504   -42.921 139.902 1.00 56.97  ? 217 THR F O   1 
ATOM   15383 C CB  . THR F 1 198 ? 6.275   -42.178 140.501 1.00 57.45  ? 217 THR F CB  1 
ATOM   15384 O OG1 . THR F 1 198 ? 4.988   -42.631 140.104 1.00 58.85  ? 217 THR F OG1 1 
ATOM   15385 C CG2 . THR F 1 198 ? 6.788   -41.118 139.551 1.00 58.00  ? 217 THR F CG2 1 
ATOM   15386 N N   . ARG F 1 199 ? 8.923   -42.510 142.050 1.00 56.28  ? 218 ARG F N   1 
ATOM   15387 C CA  . ARG F 1 199 ? 10.269  -42.089 142.428 1.00 55.42  ? 218 ARG F CA  1 
ATOM   15388 C C   . ARG F 1 199 ? 11.290  -43.194 142.214 1.00 55.86  ? 218 ARG F C   1 
ATOM   15389 O O   . ARG F 1 199 ? 12.408  -42.930 141.765 1.00 56.31  ? 218 ARG F O   1 
ATOM   15390 C CB  . ARG F 1 199 ? 10.286  -41.633 143.887 1.00 53.98  ? 218 ARG F CB  1 
ATOM   15391 C CG  . ARG F 1 199 ? 11.646  -41.274 144.387 1.00 53.23  ? 218 ARG F CG  1 
ATOM   15392 C CD  . ARG F 1 199 ? 12.235  -40.090 143.642 1.00 53.59  ? 218 ARG F CD  1 
ATOM   15393 N NE  . ARG F 1 199 ? 11.503  -38.853 143.928 1.00 53.27  ? 218 ARG F NE  1 
ATOM   15394 C CZ  . ARG F 1 199 ? 11.604  -37.712 143.247 1.00 53.89  ? 218 ARG F CZ  1 
ATOM   15395 N NH1 . ARG F 1 199 ? 12.463  -37.561 142.255 1.00 54.96  ? 218 ARG F NH1 1 
ATOM   15396 N NH2 . ARG F 1 199 ? 10.804  -36.706 143.563 1.00 53.68  ? 218 ARG F NH2 1 
ATOM   15397 N N   . GLN F 1 200 ? 10.950  -44.429 142.560 1.00 57.66  ? 219 GLN F N   1 
ATOM   15398 C CA  . GLN F 1 200 ? 11.919  -45.511 142.374 1.00 59.39  ? 219 GLN F CA  1 
ATOM   15399 C C   . GLN F 1 200 ? 12.273  -45.683 140.895 1.00 62.18  ? 219 GLN F C   1 
ATOM   15400 O O   . GLN F 1 200 ? 13.436  -45.916 140.545 1.00 64.53  ? 219 GLN F O   1 
ATOM   15401 C CB  . GLN F 1 200 ? 11.390  -46.832 142.968 1.00 60.50  ? 219 GLN F CB  1 
ATOM   15402 C CG  . GLN F 1 200 ? 10.662  -46.626 144.311 1.00 58.87  ? 219 GLN F CG  1 
ATOM   15403 C CD  . GLN F 1 200 ? 9.979   -47.887 144.932 1.00 60.35  ? 219 GLN F CD  1 
ATOM   15404 O OE1 . GLN F 1 200 ? 9.723   -48.917 144.288 1.00 62.20  ? 219 GLN F OE1 1 
ATOM   15405 N NE2 . GLN F 1 200 ? 9.672   -47.776 146.209 1.00 60.07  ? 219 GLN F NE2 1 
ATOM   15406 N N   . LYS F 1 201 ? 11.285  -45.539 140.011 1.00 60.74  ? 220 LYS F N   1 
ATOM   15407 C CA  . LYS F 1 201 ? 11.487  -45.787 138.589 1.00 63.24  ? 220 LYS F CA  1 
ATOM   15408 C C   . LYS F 1 201 ? 12.133  -44.611 137.868 1.00 62.53  ? 220 LYS F C   1 
ATOM   15409 O O   . LYS F 1 201 ? 12.798  -44.827 136.844 1.00 65.12  ? 220 LYS F O   1 
ATOM   15410 C CB  . LYS F 1 201 ? 10.144  -46.145 137.952 1.00 64.58  ? 220 LYS F CB  1 
ATOM   15411 N N   . ILE F 1 202 ? 11.955  -43.377 138.369 1.00 64.24  ? 221 ILE F N   1 
ATOM   15412 C CA  . ILE F 1 202 ? 12.448  -42.201 137.659 1.00 64.13  ? 221 ILE F CA  1 
ATOM   15413 C C   . ILE F 1 202 ? 13.706  -41.612 138.296 1.00 63.87  ? 221 ILE F C   1 
ATOM   15414 O O   . ILE F 1 202 ? 14.409  -40.833 137.640 1.00 64.83  ? 221 ILE F O   1 
ATOM   15415 C CB  . ILE F 1 202 ? 11.372  -41.097 137.526 1.00 62.78  ? 221 ILE F CB  1 
ATOM   15416 C CG1 . ILE F 1 202 ? 10.761  -40.739 138.882 1.00 60.40  ? 221 ILE F CG1 1 
ATOM   15417 C CG2 . ILE F 1 202 ? 10.234  -41.540 136.592 1.00 64.19  ? 221 ILE F CG2 1 
ATOM   15418 C CD1 . ILE F 1 202 ? 11.232  -39.456 139.406 1.00 59.45  ? 221 ILE F CD1 1 
ATOM   15419 N N   . GLY F 1 203 ? 14.020  -41.967 139.529 1.00 61.96  ? 222 GLY F N   1 
ATOM   15420 C CA  . GLY F 1 203 ? 15.271  -41.565 140.136 1.00 61.83  ? 222 GLY F CA  1 
ATOM   15421 C C   . GLY F 1 203 ? 15.101  -40.381 141.069 1.00 59.76  ? 222 GLY F C   1 
ATOM   15422 O O   . GLY F 1 203 ? 14.066  -39.718 141.113 1.00 58.41  ? 222 GLY F O   1 
ATOM   15423 N N   . ASP F 1 204 ? 16.151  -40.117 141.826 1.00 61.02  ? 223 ASP F N   1 
ATOM   15424 C CA  . ASP F 1 204 ? 16.106  -39.046 142.812 1.00 59.32  ? 223 ASP F CA  1 
ATOM   15425 C C   . ASP F 1 204 ? 16.429  -37.671 142.243 1.00 58.11  ? 223 ASP F C   1 
ATOM   15426 O O   . ASP F 1 204 ? 16.190  -36.666 142.926 1.00 57.49  ? 223 ASP F O   1 
ATOM   15427 C CB  . ASP F 1 204 ? 17.068  -39.356 143.966 1.00 60.44  ? 223 ASP F CB  1 
ATOM   15428 C CG  . ASP F 1 204 ? 16.686  -40.616 144.725 1.00 62.22  ? 223 ASP F CG  1 
ATOM   15429 O OD1 . ASP F 1 204 ? 15.504  -41.030 144.676 1.00 61.59  ? 223 ASP F OD1 1 
ATOM   15430 O OD2 . ASP F 1 204 ? 17.571  -41.192 145.392 1.00 65.23  ? 223 ASP F OD2 1 
ATOM   15431 N N   . ASP F 1 205 ? 16.957  -37.591 141.027 1.00 60.71  ? 224 ASP F N   1 
ATOM   15432 C CA  . ASP F 1 205 ? 17.266  -36.312 140.403 1.00 59.70  ? 224 ASP F CA  1 
ATOM   15433 C C   . ASP F 1 205 ? 16.217  -35.864 139.384 1.00 58.05  ? 224 ASP F C   1 
ATOM   15434 O O   . ASP F 1 205 ? 16.539  -35.060 138.507 1.00 57.65  ? 224 ASP F O   1 
ATOM   15435 C CB  . ASP F 1 205 ? 18.625  -36.392 139.710 1.00 61.95  ? 224 ASP F CB  1 
ATOM   15436 C CG  . ASP F 1 205 ? 18.597  -37.318 138.481 1.00 64.40  ? 224 ASP F CG  1 
ATOM   15437 O OD1 . ASP F 1 205 ? 17.550  -37.977 138.211 1.00 64.15  ? 224 ASP F OD1 1 
ATOM   15438 O OD2 . ASP F 1 205 ? 19.625  -37.382 137.772 1.00 67.55  ? 224 ASP F OD2 1 
ATOM   15439 N N   . LYS F 1 206 ? 15.004  -36.415 139.432 1.00 60.38  ? 225 LYS F N   1 
ATOM   15440 C CA  . LYS F 1 206 ? 13.886  -35.973 138.603 1.00 59.18  ? 225 LYS F CA  1 
ATOM   15441 C C   . LYS F 1 206 ? 12.818  -35.356 139.495 1.00 58.05  ? 225 LYS F C   1 
ATOM   15442 O O   . LYS F 1 206 ? 12.765  -35.601 140.697 1.00 58.92  ? 225 LYS F O   1 
ATOM   15443 C CB  . LYS F 1 206 ? 13.256  -37.122 137.798 1.00 60.61  ? 225 LYS F CB  1 
ATOM   15444 C CG  . LYS F 1 206 ? 14.207  -37.806 136.842 1.00 62.12  ? 225 LYS F CG  1 
ATOM   15445 C CD  . LYS F 1 206 ? 14.631  -36.855 135.763 1.00 61.44  ? 225 LYS F CD  1 
ATOM   15446 C CE  . LYS F 1 206 ? 15.567  -37.492 134.761 1.00 63.60  ? 225 LYS F CE  1 
ATOM   15447 N NZ  . LYS F 1 206 ? 15.696  -36.645 133.531 1.00 63.46  ? 225 LYS F NZ  1 
ATOM   15448 N N   . LEU F 1 207 ? 11.934  -34.581 138.904 1.00 57.21  ? 226 LEU F N   1 
ATOM   15449 C CA  . LEU F 1 207 ? 10.975  -33.824 139.687 1.00 56.22  ? 226 LEU F CA  1 
ATOM   15450 C C   . LEU F 1 207 ? 9.643   -34.530 139.698 1.00 56.77  ? 226 LEU F C   1 
ATOM   15451 O O   . LEU F 1 207 ? 9.159   -34.946 138.649 1.00 57.40  ? 226 LEU F O   1 
ATOM   15452 C CB  . LEU F 1 207 ? 10.816  -32.420 139.127 1.00 54.89  ? 226 LEU F CB  1 
ATOM   15453 C CG  . LEU F 1 207 ? 12.081  -31.594 139.414 1.00 54.58  ? 226 LEU F CG  1 
ATOM   15454 C CD1 . LEU F 1 207 ? 12.033  -30.414 138.431 1.00 53.74  ? 226 LEU F CD1 1 
ATOM   15455 C CD2 . LEU F 1 207 ? 12.239  -31.173 140.891 1.00 55.06  ? 226 LEU F CD2 1 
ATOM   15456 N N   . ILE F 1 208 ? 9.045   -34.648 140.872 1.00 52.87  ? 227 ILE F N   1 
ATOM   15457 C CA  . ILE F 1 208 ? 7.657   -35.052 140.977 1.00 53.27  ? 227 ILE F CA  1 
ATOM   15458 C C   . ILE F 1 208 ? 6.879   -33.858 141.498 1.00 52.58  ? 227 ILE F C   1 
ATOM   15459 O O   . ILE F 1 208 ? 7.123   -33.393 142.612 1.00 52.59  ? 227 ILE F O   1 
ATOM   15460 C CB  . ILE F 1 208 ? 7.459   -36.284 141.873 1.00 54.39  ? 227 ILE F CB  1 
ATOM   15461 C CG1 . ILE F 1 208 ? 8.130   -37.521 141.260 1.00 55.45  ? 227 ILE F CG1 1 
ATOM   15462 C CG2 . ILE F 1 208 ? 5.961   -36.528 142.071 1.00 54.76  ? 227 ILE F CG2 1 
ATOM   15463 C CD1 . ILE F 1 208 ? 8.000   -38.845 142.127 1.00 56.67  ? 227 ILE F CD1 1 
ATOM   15464 N N   . VAL F 1 209 ? 5.932   -33.385 140.690 1.00 57.03  ? 228 VAL F N   1 
ATOM   15465 C CA  . VAL F 1 209 ? 4.941   -32.376 141.045 1.00 56.76  ? 228 VAL F CA  1 
ATOM   15466 C C   . VAL F 1 209 ? 3.585   -33.053 141.181 1.00 57.74  ? 228 VAL F C   1 
ATOM   15467 O O   . VAL F 1 209 ? 3.309   -34.028 140.479 1.00 58.51  ? 228 VAL F O   1 
ATOM   15468 C CB  . VAL F 1 209 ? 4.889   -31.294 139.944 1.00 56.08  ? 228 VAL F CB  1 
ATOM   15469 C CG1 . VAL F 1 209 ? 4.001   -30.129 140.363 1.00 55.98  ? 228 VAL F CG1 1 
ATOM   15470 C CG2 . VAL F 1 209 ? 6.303   -30.826 139.591 1.00 55.35  ? 228 VAL F CG2 1 
ATOM   15471 N N   . TYR F 1 210 ? 2.728   -32.540 142.072 1.00 54.25  ? 229 TYR F N   1 
ATOM   15472 C CA  . TYR F 1 210 ? 1.389   -33.110 142.193 1.00 55.25  ? 229 TYR F CA  1 
ATOM   15473 C C   . TYR F 1 210 ? 0.366   -32.039 142.538 1.00 55.85  ? 229 TYR F C   1 
ATOM   15474 O O   . TYR F 1 210 ? 0.690   -30.994 143.092 1.00 55.70  ? 229 TYR F O   1 
ATOM   15475 C CB  . TYR F 1 210 ? 1.348   -34.254 143.233 1.00 56.23  ? 229 TYR F CB  1 
ATOM   15476 C CG  . TYR F 1 210 ? 1.148   -33.875 144.688 1.00 57.31  ? 229 TYR F CG  1 
ATOM   15477 C CD1 . TYR F 1 210 ? 2.243   -33.645 145.531 1.00 57.22  ? 229 TYR F CD1 1 
ATOM   15478 C CD2 . TYR F 1 210 ? -0.121  -33.809 145.240 1.00 58.78  ? 229 TYR F CD2 1 
ATOM   15479 C CE1 . TYR F 1 210 ? 2.060   -33.323 146.872 1.00 58.64  ? 229 TYR F CE1 1 
ATOM   15480 C CE2 . TYR F 1 210 ? -0.308  -33.483 146.563 1.00 60.34  ? 229 TYR F CE2 1 
ATOM   15481 C CZ  . TYR F 1 210 ? 0.772   -33.241 147.371 1.00 60.31  ? 229 TYR F CZ  1 
ATOM   15482 O OH  . TYR F 1 210 ? 0.532   -32.911 148.674 1.00 62.31  ? 229 TYR F OH  1 
ATOM   15483 N N   . ASN F 1 211 ? -0.881  -32.314 142.185 1.00 61.24  ? 230 ASN F N   1 
ATOM   15484 C CA  . ASN F 1 211 ? -2.031  -31.491 142.552 1.00 62.54  ? 230 ASN F CA  1 
ATOM   15485 C C   . ASN F 1 211 ? -2.846  -32.264 143.578 1.00 64.47  ? 230 ASN F C   1 
ATOM   15486 O O   . ASN F 1 211 ? -3.455  -33.295 143.248 1.00 65.00  ? 230 ASN F O   1 
ATOM   15487 C CB  . ASN F 1 211 ? -2.881  -31.173 141.328 1.00 62.70  ? 230 ASN F CB  1 
ATOM   15488 C CG  . ASN F 1 211 ? -3.822  -30.011 141.543 1.00 64.31  ? 230 ASN F CG  1 
ATOM   15489 O OD1 . ASN F 1 211 ? -3.849  -29.362 142.597 1.00 65.79  ? 230 ASN F OD1 1 
ATOM   15490 N ND2 . ASN F 1 211 ? -4.621  -29.740 140.518 1.00 64.95  ? 230 ASN F ND2 1 
ATOM   15491 N N   . GLY F 1 212 ? -2.832  -31.794 144.827 1.00 61.75  ? 231 GLY F N   1 
ATOM   15492 C CA  . GLY F 1 212 ? -2.051  -30.676 145.315 1.00 61.46  ? 231 GLY F CA  1 
ATOM   15493 C C   . GLY F 1 212 ? -2.680  -30.085 146.557 1.00 64.10  ? 231 GLY F C   1 
ATOM   15494 O O   . GLY F 1 212 ? -3.468  -30.722 147.228 1.00 66.72  ? 231 GLY F O   1 
ATOM   15495 N N   . ILE F 1 213 ? -2.336  -28.854 146.858 1.00 64.57  ? 232 ILE F N   1 
ATOM   15496 C CA  . ILE F 1 213 ? -2.833  -28.180 148.048 1.00 67.24  ? 232 ILE F CA  1 
ATOM   15497 C C   . ILE F 1 213 ? -4.198  -27.590 147.728 1.00 69.01  ? 232 ILE F C   1 
ATOM   15498 O O   . ILE F 1 213 ? -4.371  -26.899 146.715 1.00 67.78  ? 232 ILE F O   1 
ATOM   15499 C CB  . ILE F 1 213 ? -1.833  -27.114 148.525 1.00 66.83  ? 232 ILE F CB  1 
ATOM   15500 C CG1 . ILE F 1 213 ? -0.425  -27.732 148.555 1.00 66.13  ? 232 ILE F CG1 1 
ATOM   15501 C CG2 . ILE F 1 213 ? -2.222  -26.600 149.882 1.00 70.32  ? 232 ILE F CG2 1 
ATOM   15502 C CD1 . ILE F 1 213 ? 0.551   -27.073 149.509 1.00 65.80  ? 232 ILE F CD1 1 
ATOM   15503 N N   . ARG F 1 214 ? -5.179  -27.903 148.571 1.00 72.26  ? 233 ARG F N   1 
ATOM   15504 C CA  . ARG F 1 214 ? -6.563  -27.506 148.353 1.00 74.77  ? 233 ARG F CA  1 
ATOM   15505 C C   . ARG F 1 214 ? -7.207  -27.138 149.680 1.00 78.81  ? 233 ARG F C   1 
ATOM   15506 O O   . ARG F 1 214 ? -7.201  -27.949 150.611 1.00 80.91  ? 233 ARG F O   1 
ATOM   15507 C CB  . ARG F 1 214 ? -7.354  -28.645 147.692 1.00 75.27  ? 233 ARG F CB  1 
ATOM   15508 C CG  . ARG F 1 214 ? -8.826  -28.338 147.460 1.00 78.65  ? 233 ARG F CG  1 
ATOM   15509 C CD  . ARG F 1 214 ? -8.993  -27.285 146.384 1.00 77.58  ? 233 ARG F CD  1 
ATOM   15510 N NE  . ARG F 1 214 ? -8.157  -27.588 145.229 1.00 73.74  ? 233 ARG F NE  1 
ATOM   15511 C CZ  . ARG F 1 214 ? -8.444  -28.494 144.304 1.00 72.99  ? 233 ARG F CZ  1 
ATOM   15512 N NH1 . ARG F 1 214 ? -9.590  -29.163 144.317 1.00 75.16  ? 233 ARG F NH1 1 
ATOM   15513 N NH2 . ARG F 1 214 ? -7.560  -28.730 143.337 1.00 70.11  ? 233 ARG F NH2 1 
ATOM   15514 N N   . SER F 1 215 ? -7.783  -25.935 149.764 1.00 78.09  ? 234 SER F N   1 
ATOM   15515 C CA  . SER F 1 215 ? -8.482  -25.505 150.969 1.00 82.19  ? 234 SER F CA  1 
ATOM   15516 C C   . SER F 1 215 ? -9.889  -25.046 150.627 1.00 84.73  ? 234 SER F C   1 
ATOM   15517 O O   . SER F 1 215 ? -10.067 -24.065 149.899 1.00 83.48  ? 234 SER F O   1 
ATOM   15518 C CB  . SER F 1 215 ? -7.699  -24.401 151.690 1.00 82.26  ? 234 SER F CB  1 
ATOM   15519 O OG  . SER F 1 215 ? -6.450  -24.929 152.138 1.00 80.75  ? 234 SER F OG  1 
ATOM   15520 N N   . THR F 1 216 ? -10.859 -25.784 151.132 1.00 83.90  ? 235 THR F N   1 
ATOM   15521 C CA  . THR F 1 216 ? -12.296 -25.478 151.032 1.00 87.41  ? 235 THR F CA  1 
ATOM   15522 C C   . THR F 1 216 ? -12.865 -25.535 152.437 1.00 92.66  ? 235 THR F C   1 
ATOM   15523 O O   . THR F 1 216 ? -12.200 -25.951 153.388 1.00 94.21  ? 235 THR F O   1 
ATOM   15524 C CB  . THR F 1 216 ? -13.033 -26.463 150.106 1.00 87.60  ? 235 THR F CB  1 
ATOM   15525 O OG1 . THR F 1 216 ? -13.163 -27.765 150.706 1.00 90.56  ? 235 THR F OG1 1 
ATOM   15526 C CG2 . THR F 1 216 ? -12.317 -26.583 148.743 1.00 83.07  ? 235 THR F CG2 1 
ATOM   15527 N N   . PRO F 1 217 ? -14.116 -25.090 152.596 1.00 88.26  ? 236 PRO F N   1 
ATOM   15528 C CA  . PRO F 1 217 ? -14.764 -25.186 153.920 1.00 93.61  ? 236 PRO F CA  1 
ATOM   15529 C C   . PRO F 1 217 ? -15.004 -26.609 154.403 1.00 97.66  ? 236 PRO F C   1 
ATOM   15530 O O   . PRO F 1 217 ? -14.832 -26.886 155.598 1.00 101.70 ? 236 PRO F O   1 
ATOM   15531 C CB  . PRO F 1 217 ? -16.089 -24.433 153.700 1.00 94.95  ? 236 PRO F CB  1 
ATOM   15532 C CG  . PRO F 1 217 ? -15.803 -23.476 152.558 1.00 91.10  ? 236 PRO F CG  1 
ATOM   15533 C CD  . PRO F 1 217 ? -14.872 -24.243 151.654 1.00 87.30  ? 236 PRO F CD  1 
ATOM   15534 N N   . ASP F 1 218 ? -15.410 -27.522 153.517 1.00 93.76  ? 237 ASP F N   1 
ATOM   15535 C CA  . ASP F 1 218 ? -15.762 -28.876 153.936 1.00 97.30  ? 237 ASP F CA  1 
ATOM   15536 C C   . ASP F 1 218 ? -14.555 -29.809 153.991 1.00 95.06  ? 237 ASP F C   1 
ATOM   15537 O O   . ASP F 1 218 ? -14.527 -30.717 154.829 1.00 96.76  ? 237 ASP F O   1 
ATOM   15538 C CB  . ASP F 1 218 ? -16.839 -29.434 152.996 1.00 97.11  ? 237 ASP F CB  1 
ATOM   15539 N N   . TRP F 1 219 ? -13.547 -29.581 153.150 1.00 98.95  ? 238 TRP F N   1 
ATOM   15540 C CA  . TRP F 1 219 ? -12.411 -30.483 153.000 1.00 93.99  ? 238 TRP F CA  1 
ATOM   15541 C C   . TRP F 1 219 ? -11.197 -29.648 152.619 1.00 89.69  ? 238 TRP F C   1 
ATOM   15542 O O   . TRP F 1 219 ? -11.299 -28.697 151.836 1.00 88.05  ? 238 TRP F O   1 
ATOM   15543 C CB  . TRP F 1 219 ? -12.710 -31.550 151.941 1.00 91.37  ? 238 TRP F CB  1 
ATOM   15544 C CG  . TRP F 1 219 ? -11.587 -32.504 151.540 1.00 87.29  ? 238 TRP F CG  1 
ATOM   15545 C CD1 . TRP F 1 219 ? -11.247 -33.693 152.143 1.00 87.32  ? 238 TRP F CD1 1 
ATOM   15546 C CD2 . TRP F 1 219 ? -10.712 -32.376 150.407 1.00 82.69  ? 238 TRP F CD2 1 
ATOM   15547 N NE1 . TRP F 1 219 ? -10.212 -34.302 151.462 1.00 83.20  ? 238 TRP F NE1 1 
ATOM   15548 C CE2 . TRP F 1 219 ? -9.861  -33.513 150.397 1.00 80.23  ? 238 TRP F CE2 1 
ATOM   15549 C CE3 . TRP F 1 219 ? -10.560 -31.408 149.400 1.00 80.47  ? 238 TRP F CE3 1 
ATOM   15550 C CZ2 . TRP F 1 219 ? -8.873  -33.699 149.427 1.00 75.87  ? 238 TRP F CZ2 1 
ATOM   15551 C CZ3 . TRP F 1 219 ? -9.571  -31.597 148.434 1.00 76.17  ? 238 TRP F CZ3 1 
ATOM   15552 C CH2 . TRP F 1 219 ? -8.746  -32.735 148.455 1.00 74.10  ? 238 TRP F CH2 1 
ATOM   15553 N N   . SER F 1 220 ? -10.050 -30.000 153.193 1.00 86.83  ? 239 SER F N   1 
ATOM   15554 C CA  . SER F 1 220 ? -8.804  -29.298 152.911 1.00 82.96  ? 239 SER F CA  1 
ATOM   15555 C C   . SER F 1 220 ? -7.674  -30.317 152.853 1.00 79.01  ? 239 SER F C   1 
ATOM   15556 O O   . SER F 1 220 ? -7.796  -31.437 153.353 1.00 80.92  ? 239 SER F O   1 
ATOM   15557 C CB  . SER F 1 220 ? -8.542  -28.202 153.957 1.00 85.85  ? 239 SER F CB  1 
ATOM   15558 O OG  . SER F 1 220 ? -9.712  -27.417 154.185 1.00 89.84  ? 239 SER F OG  1 
ATOM   15559 N N   . ALA F 1 221 ? -6.583  -29.917 152.195 1.00 77.01  ? 240 ALA F N   1 
ATOM   15560 C CA  . ALA F 1 221 ? -5.394  -30.743 152.037 1.00 73.60  ? 240 ALA F CA  1 
ATOM   15561 C C   . ALA F 1 221 ? -4.173  -29.839 151.961 1.00 70.94  ? 240 ALA F C   1 
ATOM   15562 O O   . ALA F 1 221 ? -4.158  -28.881 151.188 1.00 69.37  ? 240 ALA F O   1 
ATOM   15563 C CB  . ALA F 1 221 ? -5.476  -31.605 150.775 1.00 71.30  ? 240 ALA F CB  1 
ATOM   15564 N N   . GLY F 1 222 ? -3.154  -30.147 152.740 1.00 69.14  ? 241 GLY F N   1 
ATOM   15565 C CA  . GLY F 1 222 ? -1.893  -29.443 152.682 1.00 66.88  ? 241 GLY F CA  1 
ATOM   15566 C C   . GLY F 1 222 ? -0.931  -30.099 151.720 1.00 63.39  ? 241 GLY F C   1 
ATOM   15567 O O   . GLY F 1 222 ? -1.320  -30.789 150.775 1.00 62.48  ? 241 GLY F O   1 
ATOM   15568 N N   . PHE F 1 223 ? 0.352   -29.836 151.948 1.00 62.89  ? 242 PHE F N   1 
ATOM   15569 C CA  . PHE F 1 223 ? 1.435   -30.579 151.320 1.00 60.11  ? 242 PHE F CA  1 
ATOM   15570 C C   . PHE F 1 223 ? 1.572   -31.848 152.147 1.00 61.69  ? 242 PHE F C   1 
ATOM   15571 O O   . PHE F 1 223 ? 2.424   -31.967 153.034 1.00 63.85  ? 242 PHE F O   1 
ATOM   15572 C CB  . PHE F 1 223 ? 2.717   -29.770 151.296 1.00 58.76  ? 242 PHE F CB  1 
ATOM   15573 C CG  . PHE F 1 223 ? 3.610   -30.064 150.123 1.00 55.86  ? 242 PHE F CG  1 
ATOM   15574 C CD1 . PHE F 1 223 ? 4.040   -31.355 149.865 1.00 55.54  ? 242 PHE F CD1 1 
ATOM   15575 C CD2 . PHE F 1 223 ? 4.029   -29.048 149.287 1.00 54.13  ? 242 PHE F CD2 1 
ATOM   15576 C CE1 . PHE F 1 223 ? 4.869   -31.627 148.800 1.00 53.77  ? 242 PHE F CE1 1 
ATOM   15577 C CE2 . PHE F 1 223 ? 4.862   -29.319 148.221 1.00 52.31  ? 242 PHE F CE2 1 
ATOM   15578 C CZ  . PHE F 1 223 ? 5.289   -30.623 147.985 1.00 52.08  ? 242 PHE F CZ  1 
ATOM   15579 N N   . ASP F 1 224 ? 0.665   -32.789 151.898 1.00 60.77  ? 243 ASP F N   1 
ATOM   15580 C CA  . ASP F 1 224 ? 0.543   -34.011 152.681 1.00 63.08  ? 243 ASP F CA  1 
ATOM   15581 C C   . ASP F 1 224 ? 1.487   -35.077 152.158 1.00 60.64  ? 243 ASP F C   1 
ATOM   15582 O O   . ASP F 1 224 ? 2.255   -35.656 152.917 1.00 61.55  ? 243 ASP F O   1 
ATOM   15583 C CB  . ASP F 1 224 ? -0.902  -34.517 152.649 1.00 66.31  ? 243 ASP F CB  1 
ATOM   15584 C CG  . ASP F 1 224 ? -1.874  -33.552 153.330 1.00 70.92  ? 243 ASP F CG  1 
ATOM   15585 O OD1 . ASP F 1 224 ? -1.415  -32.725 154.147 1.00 71.95  ? 243 ASP F OD1 1 
ATOM   15586 O OD2 . ASP F 1 224 ? -3.090  -33.599 153.042 1.00 73.46  ? 243 ASP F OD2 1 
ATOM   15587 N N   . PHE F 1 225 ? 1.481   -35.306 150.866 1.00 64.17  ? 244 PHE F N   1 
ATOM   15588 C CA  . PHE F 1 225 ? 2.389   -36.264 150.274 1.00 62.64  ? 244 PHE F CA  1 
ATOM   15589 C C   . PHE F 1 225 ? 3.734   -35.616 150.088 1.00 60.98  ? 244 PHE F C   1 
ATOM   15590 O O   . PHE F 1 225 ? 3.914   -34.823 149.177 1.00 59.37  ? 244 PHE F O   1 
ATOM   15591 C CB  . PHE F 1 225 ? 1.892   -36.748 148.936 1.00 61.66  ? 244 PHE F CB  1 
ATOM   15592 C CG  . PHE F 1 225 ? 0.593   -37.460 149.021 1.00 63.17  ? 244 PHE F CG  1 
ATOM   15593 C CD1 . PHE F 1 225 ? -0.570  -36.790 149.431 1.00 64.09  ? 244 PHE F CD1 1 
ATOM   15594 C CD2 . PHE F 1 225 ? 0.529   -38.815 148.686 1.00 64.33  ? 244 PHE F CD2 1 
ATOM   15595 C CE1 . PHE F 1 225 ? -1.773  -37.460 149.496 1.00 65.45  ? 244 PHE F CE1 1 
ATOM   15596 C CE2 . PHE F 1 225 ? -0.654  -39.497 148.719 1.00 65.87  ? 244 PHE F CE2 1 
ATOM   15597 C CZ  . PHE F 1 225 ? -1.824  -38.831 149.137 1.00 66.41  ? 244 PHE F CZ  1 
ATOM   15598 N N   . ALA F 1 226 ? 4.712   -36.016 150.902 1.00 61.36  ? 245 ALA F N   1 
ATOM   15599 C CA  . ALA F 1 226 ? 5.928   -35.244 150.949 1.00 60.43  ? 245 ALA F CA  1 
ATOM   15600 C C   . ALA F 1 226 ? 7.180   -36.094 150.845 1.00 59.96  ? 245 ALA F C   1 
ATOM   15601 O O   . ALA F 1 226 ? 8.181   -35.615 150.323 1.00 58.64  ? 245 ALA F O   1 
ATOM   15602 C CB  . ALA F 1 226 ? 5.950   -34.411 152.227 1.00 62.38  ? 245 ALA F CB  1 
ATOM   15603 N N   . GLU F 1 227 ? 7.133   -37.340 151.335 1.00 62.73  ? 246 GLU F N   1 
ATOM   15604 C CA  . GLU F 1 227 ? 8.372   -38.121 151.417 1.00 62.43  ? 246 GLU F CA  1 
ATOM   15605 C C   . GLU F 1 227 ? 8.992   -38.350 150.041 1.00 60.92  ? 246 GLU F C   1 
ATOM   15606 O O   . GLU F 1 227 ? 10.204  -38.594 149.943 1.00 60.94  ? 246 GLU F O   1 
ATOM   15607 C CB  . GLU F 1 227 ? 8.138   -39.470 152.120 1.00 64.12  ? 246 GLU F CB  1 
ATOM   15608 C CG  . GLU F 1 227 ? 9.188   -40.551 151.845 1.00 64.99  ? 246 GLU F CG  1 
ATOM   15609 C CD  . GLU F 1 227 ? 10.379  -40.605 152.874 1.00 67.02  ? 246 GLU F CD  1 
ATOM   15610 O OE1 . GLU F 1 227 ? 11.572  -40.683 152.424 1.00 68.72  ? 246 GLU F OE1 1 
ATOM   15611 O OE2 . GLU F 1 227 ? 10.159  -40.634 154.110 1.00 67.06  ? 246 GLU F OE2 1 
ATOM   15612 N N   . TYR F 1 228 ? 8.192   -38.348 148.972 1.00 55.33  ? 247 TYR F N   1 
ATOM   15613 C CA  . TYR F 1 228 ? 8.705   -38.708 147.665 1.00 54.59  ? 247 TYR F CA  1 
ATOM   15614 C C   . TYR F 1 228 ? 8.383   -37.659 146.625 1.00 52.96  ? 247 TYR F C   1 
ATOM   15615 O O   . TYR F 1 228 ? 8.898   -37.742 145.508 1.00 53.18  ? 247 TYR F O   1 
ATOM   15616 C CB  . TYR F 1 228 ? 8.157   -40.077 147.253 1.00 55.43  ? 247 TYR F CB  1 
ATOM   15617 C CG  . TYR F 1 228 ? 8.589   -41.205 148.218 1.00 56.77  ? 247 TYR F CG  1 
ATOM   15618 C CD1 . TYR F 1 228 ? 9.914   -41.612 148.292 1.00 57.31  ? 247 TYR F CD1 1 
ATOM   15619 C CD2 . TYR F 1 228 ? 7.675   -41.849 149.049 1.00 57.96  ? 247 TYR F CD2 1 
ATOM   15620 C CE1 . TYR F 1 228 ? 10.315  -42.610 149.136 1.00 58.69  ? 247 TYR F CE1 1 
ATOM   15621 C CE2 . TYR F 1 228 ? 8.071   -42.869 149.903 1.00 59.58  ? 247 TYR F CE2 1 
ATOM   15622 C CZ  . TYR F 1 228 ? 9.404   -43.238 149.956 1.00 59.68  ? 247 TYR F CZ  1 
ATOM   15623 O OH  . TYR F 1 228 ? 9.866   -44.224 150.821 1.00 61.64  ? 247 TYR F OH  1 
ATOM   15624 N N   . THR F 1 229 ? 7.632   -36.628 146.983 1.00 55.97  ? 248 THR F N   1 
ATOM   15625 C CA  . THR F 1 229 ? 7.274   -35.531 146.101 1.00 54.86  ? 248 THR F CA  1 
ATOM   15626 C C   . THR F 1 229 ? 8.155   -34.319 146.367 1.00 53.94  ? 248 THR F C   1 
ATOM   15627 O O   . THR F 1 229 ? 8.679   -34.139 147.472 1.00 55.01  ? 248 THR F O   1 
ATOM   15628 C CB  . THR F 1 229 ? 5.806   -35.157 146.323 1.00 55.77  ? 248 THR F CB  1 
ATOM   15629 O OG1 . THR F 1 229 ? 5.533   -35.238 147.736 1.00 57.34  ? 248 THR F OG1 1 
ATOM   15630 C CG2 . THR F 1 229 ? 4.905   -36.143 145.588 1.00 56.35  ? 248 THR F CG2 1 
ATOM   15631 N N   . ASP F 1 230 ? 8.304   -33.492 145.325 1.00 51.62  ? 249 ASP F N   1 
ATOM   15632 C CA  . ASP F 1 230 ? 9.044   -32.234 145.378 1.00 50.88  ? 249 ASP F CA  1 
ATOM   15633 C C   . ASP F 1 230 ? 8.168   -31.002 145.398 1.00 50.83  ? 249 ASP F C   1 
ATOM   15634 O O   . ASP F 1 230 ? 8.481   -30.046 146.089 1.00 50.75  ? 249 ASP F O   1 
ATOM   15635 C CB  . ASP F 1 230 ? 9.980   -32.114 144.176 1.00 50.32  ? 249 ASP F CB  1 
ATOM   15636 C CG  . ASP F 1 230 ? 11.042  -33.183 144.166 1.00 51.17  ? 249 ASP F CG  1 
ATOM   15637 O OD1 . ASP F 1 230 ? 11.865  -33.271 145.132 1.00 52.08  ? 249 ASP F OD1 1 
ATOM   15638 O OD2 . ASP F 1 230 ? 11.055  -33.921 143.169 1.00 51.31  ? 249 ASP F OD2 1 
ATOM   15639 N N   . ALA F 1 231 ? 7.084   -30.992 144.644 1.00 53.43  ? 250 ALA F N   1 
ATOM   15640 C CA  . ALA F 1 231 ? 6.354   -29.757 144.376 1.00 52.98  ? 250 ALA F CA  1 
ATOM   15641 C C   . ALA F 1 231 ? 4.866   -30.040 144.461 1.00 53.72  ? 250 ALA F C   1 
ATOM   15642 O O   . ALA F 1 231 ? 4.423   -31.139 144.113 1.00 54.21  ? 250 ALA F O   1 
ATOM   15643 C CB  . ALA F 1 231 ? 6.706   -29.176 143.003 1.00 52.00  ? 250 ALA F CB  1 
ATOM   15644 N N   . ALA F 1 232 ? 4.117   -29.067 144.962 1.00 55.41  ? 251 ALA F N   1 
ATOM   15645 C CA  . ALA F 1 232 ? 2.674   -29.163 145.052 1.00 56.60  ? 251 ALA F CA  1 
ATOM   15646 C C   . ALA F 1 232 ? 2.081   -27.854 144.561 1.00 56.53  ? 251 ALA F C   1 
ATOM   15647 O O   . ALA F 1 232 ? 2.629   -26.780 144.827 1.00 56.46  ? 251 ALA F O   1 
ATOM   15648 C CB  . ALA F 1 232 ? 2.195   -29.443 146.470 1.00 58.82  ? 251 ALA F CB  1 
ATOM   15649 N N   . MET F 1 233 ? 0.963   -27.948 143.853 1.00 62.75  ? 252 MET F N   1 
ATOM   15650 C CA  . MET F 1 233 ? 0.303   -26.802 143.263 1.00 62.76  ? 252 MET F CA  1 
ATOM   15651 C C   . MET F 1 233 ? -0.931  -26.456 144.082 1.00 65.11  ? 252 MET F C   1 
ATOM   15652 O O   . MET F 1 233 ? -1.589  -27.339 144.637 1.00 66.85  ? 252 MET F O   1 
ATOM   15653 C CB  . MET F 1 233 ? -0.043  -27.097 141.810 1.00 62.58  ? 252 MET F CB  1 
ATOM   15654 C CG  . MET F 1 233 ? -0.687  -25.948 141.081 1.00 63.43  ? 252 MET F CG  1 
ATOM   15655 S SD  . MET F 1 233 ? -1.894  -26.676 139.980 1.00 64.54  ? 252 MET F SD  1 
ATOM   15656 C CE  . MET F 1 233 ? -0.909  -26.733 138.472 1.00 63.43  ? 252 MET F CE  1 
ATOM   15657 N N   . ILE F 1 234 ? -1.200  -25.151 144.190 1.00 62.99  ? 253 ILE F N   1 
ATOM   15658 C CA  . ILE F 1 234 ? -2.450  -24.637 144.739 1.00 65.20  ? 253 ILE F CA  1 
ATOM   15659 C C   . ILE F 1 234 ? -3.320  -24.160 143.588 1.00 65.06  ? 253 ILE F C   1 
ATOM   15660 O O   . ILE F 1 234 ? -3.345  -22.962 143.286 1.00 64.91  ? 253 ILE F O   1 
ATOM   15661 C CB  . ILE F 1 234 ? -2.198  -23.502 145.743 1.00 66.47  ? 253 ILE F CB  1 
ATOM   15662 C CG1 . ILE F 1 234 ? -0.930  -23.827 146.527 1.00 66.79  ? 253 ILE F CG1 1 
ATOM   15663 C CG2 . ILE F 1 234 ? -3.395  -23.341 146.636 1.00 69.89  ? 253 ILE F CG2 1 
ATOM   15664 C CD1 . ILE F 1 234 ? -0.732  -22.997 147.786 1.00 67.82  ? 253 ILE F CD1 1 
ATOM   15665 N N   . GLU F 1 235 ? -4.062  -25.093 142.967 1.00 67.34  ? 254 GLU F N   1 
ATOM   15666 C CA  . GLU F 1 235 ? -4.765  -24.811 141.718 1.00 67.00  ? 254 GLU F CA  1 
ATOM   15667 C C   . GLU F 1 235 ? -5.882  -23.796 141.919 1.00 68.84  ? 254 GLU F C   1 
ATOM   15668 O O   . GLU F 1 235 ? -6.091  -22.915 141.076 1.00 68.41  ? 254 GLU F O   1 
ATOM   15669 C CB  . GLU F 1 235 ? -5.339  -26.095 141.118 1.00 67.59  ? 254 GLU F CB  1 
ATOM   15670 N N   . HIS F 1 236 ? -6.603  -23.890 143.031 1.00 69.87  ? 255 HIS F N   1 
ATOM   15671 C CA  . HIS F 1 236 ? -7.846  -23.152 143.202 1.00 72.06  ? 255 HIS F CA  1 
ATOM   15672 C C   . HIS F 1 236 ? -7.686  -21.896 144.050 1.00 72.96  ? 255 HIS F C   1 
ATOM   15673 O O   . HIS F 1 236 ? -8.677  -21.408 144.604 1.00 75.69  ? 255 HIS F O   1 
ATOM   15674 C CB  . HIS F 1 236 ? -8.900  -24.084 143.819 1.00 75.24  ? 255 HIS F CB  1 
ATOM   15675 C CG  . HIS F 1 236 ? -9.449  -25.106 142.865 1.00 75.35  ? 255 HIS F CG  1 
ATOM   15676 N ND1 . HIS F 1 236 ? -10.616 -25.797 143.113 1.00 78.08  ? 255 HIS F ND1 1 
ATOM   15677 C CD2 . HIS F 1 236 ? -8.997  -25.548 141.665 1.00 73.27  ? 255 HIS F CD2 1 
ATOM   15678 C CE1 . HIS F 1 236 ? -10.868 -26.604 142.097 1.00 77.33  ? 255 HIS F CE1 1 
ATOM   15679 N NE2 . HIS F 1 236 ? -9.901  -26.472 141.207 1.00 74.73  ? 255 HIS F NE2 1 
ATOM   15680 N N   . PHE F 1 237 ? -6.481  -21.337 144.139 1.00 71.28  ? 256 PHE F N   1 
ATOM   15681 C CA  . PHE F 1 237 ? -6.294  -20.196 145.025 1.00 72.18  ? 256 PHE F CA  1 
ATOM   15682 C C   . PHE F 1 237 ? -7.260  -19.044 144.713 1.00 73.36  ? 256 PHE F C   1 
ATOM   15683 O O   . PHE F 1 237 ? -7.219  -18.434 143.631 1.00 71.74  ? 256 PHE F O   1 
ATOM   15684 C CB  . PHE F 1 237 ? -4.864  -19.670 144.971 1.00 70.05  ? 256 PHE F CB  1 
ATOM   15685 C CG  . PHE F 1 237 ? -4.641  -18.528 145.925 1.00 71.62  ? 256 PHE F CG  1 
ATOM   15686 C CD1 . PHE F 1 237 ? -4.528  -18.768 147.286 1.00 73.95  ? 256 PHE F CD1 1 
ATOM   15687 C CD2 . PHE F 1 237 ? -4.639  -17.222 145.487 1.00 71.50  ? 256 PHE F CD2 1 
ATOM   15688 C CE1 . PHE F 1 237 ? -4.359  -17.720 148.183 1.00 75.58  ? 256 PHE F CE1 1 
ATOM   15689 C CE2 . PHE F 1 237 ? -4.481  -16.204 146.371 1.00 73.37  ? 256 PHE F CE2 1 
ATOM   15690 C CZ  . PHE F 1 237 ? -4.339  -16.441 147.719 1.00 75.23  ? 256 PHE F CZ  1 
ATOM   15691 N N   . GLY F 1 238 ? -8.102  -18.726 145.693 1.00 76.37  ? 257 GLY F N   1 
ATOM   15692 C CA  . GLY F 1 238 ? -8.984  -17.596 145.619 1.00 77.72  ? 257 GLY F CA  1 
ATOM   15693 C C   . GLY F 1 238 ? -10.212 -17.797 144.761 1.00 78.36  ? 257 GLY F C   1 
ATOM   15694 O O   . GLY F 1 238 ? -11.005 -16.858 144.612 1.00 79.69  ? 257 GLY F O   1 
ATOM   15695 N N   . HIS F 1 239 ? -10.399 -18.971 144.170 1.00 80.02  ? 258 HIS F N   1 
ATOM   15696 C CA  . HIS F 1 239 ? -11.547 -19.206 143.325 1.00 80.79  ? 258 HIS F CA  1 
ATOM   15697 C C   . HIS F 1 239 ? -12.162 -20.553 143.652 1.00 82.67  ? 258 HIS F C   1 
ATOM   15698 O O   . HIS F 1 239 ? -11.748 -21.241 144.590 1.00 83.88  ? 258 HIS F O   1 
ATOM   15699 C CB  . HIS F 1 239 ? -11.167 -19.136 141.853 1.00 78.23  ? 258 HIS F CB  1 
ATOM   15700 C CG  . HIS F 1 239 ? -10.751 -17.774 141.417 1.00 77.49  ? 258 HIS F CG  1 
ATOM   15701 N ND1 . HIS F 1 239 ? -10.587 -16.732 142.301 1.00 79.41  ? 258 HIS F ND1 1 
ATOM   15702 C CD2 . HIS F 1 239 ? -10.555 -17.253 140.185 1.00 77.54  ? 258 HIS F CD2 1 
ATOM   15703 C CE1 . HIS F 1 239 ? -10.241 -15.644 141.637 1.00 79.82  ? 258 HIS F CE1 1 
ATOM   15704 N NE2 . HIS F 1 239 ? -10.206 -15.934 140.350 1.00 78.99  ? 258 HIS F NE2 1 
ATOM   15705 N N   . PHE F 1 240 ? -13.178 -20.925 142.865 1.00 82.21  ? 259 PHE F N   1 
ATOM   15706 C CA  . PHE F 1 240 ? -13.887 -22.190 143.031 1.00 84.06  ? 259 PHE F CA  1 
ATOM   15707 C C   . PHE F 1 240 ? -14.427 -22.218 144.447 1.00 88.10  ? 259 PHE F C   1 
ATOM   15708 O O   . PHE F 1 240 ? -15.150 -21.276 144.820 1.00 90.47  ? 259 PHE F O   1 
ATOM   15709 C CB  . PHE F 1 240 ? -12.933 -23.331 142.671 1.00 82.34  ? 259 PHE F CB  1 
ATOM   15710 C CG  . PHE F 1 240 ? -12.317 -23.215 141.313 1.00 78.91  ? 259 PHE F CG  1 
ATOM   15711 C CD1 . PHE F 1 240 ? -11.105 -22.561 141.150 1.00 79.20  ? 259 PHE F CD1 1 
ATOM   15712 C CD2 . PHE F 1 240 ? -12.957 -23.736 140.194 1.00 75.40  ? 259 PHE F CD2 1 
ATOM   15713 C CE1 . PHE F 1 240 ? -10.527 -22.435 139.884 1.00 76.02  ? 259 PHE F CE1 1 
ATOM   15714 C CE2 . PHE F 1 240 ? -12.393 -23.616 138.932 1.00 73.15  ? 259 PHE F CE2 1 
ATOM   15715 C CZ  . PHE F 1 240 ? -11.177 -22.965 138.771 1.00 73.49  ? 259 PHE F CZ  1 
ATOM   15716 N N   . GLN F 1 241 ? -14.099 -23.219 145.261 1.00 80.86  ? 260 GLN F N   1 
ATOM   15717 C CA  . GLN F 1 241 ? -14.532 -23.336 146.644 1.00 85.00  ? 260 GLN F CA  1 
ATOM   15718 C C   . GLN F 1 241 ? -13.463 -22.854 147.631 1.00 84.32  ? 260 GLN F C   1 
ATOM   15719 O O   . GLN F 1 241 ? -13.521 -23.196 148.817 1.00 87.02  ? 260 GLN F O   1 
ATOM   15720 C CB  . GLN F 1 241 ? -14.905 -24.797 146.957 1.00 87.86  ? 260 GLN F CB  1 
ATOM   15721 C CG  . GLN F 1 241 ? -16.048 -25.415 146.123 1.00 89.75  ? 260 GLN F CG  1 
ATOM   15722 C CD  . GLN F 1 241 ? -16.368 -26.845 146.560 1.00 93.21  ? 260 GLN F CD  1 
ATOM   15723 O OE1 . GLN F 1 241 ? -15.992 -27.271 147.653 1.00 96.09  ? 260 GLN F OE1 1 
ATOM   15724 N NE2 . GLN F 1 241 ? -17.053 -27.589 145.708 1.00 92.48  ? 260 GLN F NE2 1 
ATOM   15725 N N   . SER F 1 242 ? -12.486 -22.065 147.169 1.00 84.80  ? 261 SER F N   1 
ATOM   15726 C CA  . SER F 1 242 ? -11.400 -21.580 148.018 1.00 83.83  ? 261 SER F CA  1 
ATOM   15727 C C   . SER F 1 242 ? -11.287 -20.052 148.015 1.00 83.49  ? 261 SER F C   1 
ATOM   15728 O O   . SER F 1 242 ? -10.213 -19.515 148.319 1.00 82.42  ? 261 SER F O   1 
ATOM   15729 C CB  . SER F 1 242 ? -10.071 -22.219 147.585 1.00 80.46  ? 261 SER F CB  1 
ATOM   15730 O OG  . SER F 1 242 ? -10.183 -23.631 147.463 1.00 80.62  ? 261 SER F OG  1 
ATOM   15731 N N   . ALA F 1 243 ? -12.376 -19.333 147.721 1.00 82.05  ? 262 ALA F N   1 
ATOM   15732 C CA  . ALA F 1 243 ? -12.318 -17.879 147.587 1.00 81.78  ? 262 ALA F CA  1 
ATOM   15733 C C   . ALA F 1 243 ? -12.535 -17.113 148.895 1.00 84.97  ? 262 ALA F C   1 
ATOM   15734 O O   . ALA F 1 243 ? -12.468 -15.880 148.887 1.00 85.15  ? 262 ALA F O   1 
ATOM   15735 C CB  . ALA F 1 243 ? -13.350 -17.376 146.561 1.00 82.12  ? 262 ALA F CB  1 
ATOM   15736 N N   . SER F 1 244 ? -12.794 -17.797 150.006 1.00 82.51  ? 263 SER F N   1 
ATOM   15737 C CA  . SER F 1 244 ? -12.966 -17.129 151.288 1.00 84.89  ? 263 SER F CA  1 
ATOM   15738 C C   . SER F 1 244 ? -11.613 -16.775 151.912 1.00 83.63  ? 263 SER F C   1 
ATOM   15739 O O   . SER F 1 244 ? -10.580 -17.395 151.621 1.00 81.13  ? 263 SER F O   1 
ATOM   15740 C CB  . SER F 1 244 ? -13.748 -18.020 152.248 1.00 88.49  ? 263 SER F CB  1 
ATOM   15741 O OG  . SER F 1 244 ? -12.941 -19.105 152.652 1.00 88.19  ? 263 SER F OG  1 
ATOM   15742 N N   . LYS F 1 245 ? -11.631 -15.760 152.795 1.00 83.97  ? 264 LYS F N   1 
ATOM   15743 C CA  . LYS F 1 245 ? -10.398 -15.290 153.438 1.00 82.72  ? 264 LYS F CA  1 
ATOM   15744 C C   . LYS F 1 245 ? -9.810  -16.323 154.407 1.00 81.07  ? 264 LYS F C   1 
ATOM   15745 O O   . LYS F 1 245 ? -8.608  -16.281 154.701 1.00 79.29  ? 264 LYS F O   1 
ATOM   15746 C CB  . LYS F 1 245 ? -10.646 -13.951 154.161 1.00 84.84  ? 264 LYS F CB  1 
ATOM   15747 C CG  . LYS F 1 245 ? -11.652 -13.973 155.312 1.00 86.63  ? 264 LYS F CG  1 
ATOM   15748 C CD  . LYS F 1 245 ? -12.998 -13.471 154.836 1.00 89.56  ? 264 LYS F CD  1 
ATOM   15749 C CE  . LYS F 1 245 ? -14.038 -13.481 155.927 1.00 91.49  ? 264 LYS F CE  1 
ATOM   15750 N NZ  . LYS F 1 245 ? -15.351 -13.215 155.306 1.00 93.89  ? 264 LYS F NZ  1 
ATOM   15751 N N   . GLU F 1 246 ? -10.629 -17.249 154.909 1.00 83.34  ? 265 GLU F N   1 
ATOM   15752 C CA  . GLU F 1 246 ? -10.105 -18.326 155.740 1.00 82.50  ? 265 GLU F CA  1 
ATOM   15753 C C   . GLU F 1 246 ? -9.353  -19.353 154.896 1.00 80.34  ? 265 GLU F C   1 
ATOM   15754 O O   . GLU F 1 246 ? -8.274  -19.808 155.286 1.00 79.11  ? 265 GLU F O   1 
ATOM   15755 C CB  . GLU F 1 246 ? -11.259 -18.988 156.502 1.00 84.32  ? 265 GLU F CB  1 
ATOM   15756 C CG  . GLU F 1 246 ? -12.059 -18.064 157.439 1.00 86.41  ? 265 GLU F CG  1 
ATOM   15757 C CD  . GLU F 1 246 ? -13.239 -17.377 156.754 1.00 88.32  ? 265 GLU F CD  1 
ATOM   15758 O OE1 . GLU F 1 246 ? -13.580 -17.761 155.611 1.00 89.09  ? 265 GLU F OE1 1 
ATOM   15759 O OE2 . GLU F 1 246 ? -13.826 -16.451 157.365 1.00 89.35  ? 265 GLU F OE2 1 
ATOM   15760 N N   . THR F 1 247 ? -9.910  -19.741 153.746 1.00 81.88  ? 266 THR F N   1 
ATOM   15761 C CA  . THR F 1 247 ? -9.219  -20.687 152.877 1.00 80.28  ? 266 THR F CA  1 
ATOM   15762 C C   . THR F 1 247 ? -8.017  -20.029 152.208 1.00 78.52  ? 266 THR F C   1 
ATOM   15763 O O   . THR F 1 247 ? -6.964  -20.654 152.053 1.00 77.08  ? 266 THR F O   1 
ATOM   15764 C CB  . THR F 1 247 ? -10.181 -21.253 151.830 1.00 81.50  ? 266 THR F CB  1 
ATOM   15765 O OG1 . THR F 1 247 ? -10.771 -20.184 151.087 1.00 82.57  ? 266 THR F OG1 1 
ATOM   15766 C CG2 . THR F 1 247 ? -11.285 -22.048 152.476 1.00 83.07  ? 266 THR F CG2 1 
ATOM   15767 N N   . MET F 1 248 ? -8.150  -18.763 151.815 1.00 77.80  ? 267 MET F N   1 
ATOM   15768 C CA  . MET F 1 248 ? -7.024  -18.055 151.213 1.00 76.48  ? 267 MET F CA  1 
ATOM   15769 C C   . MET F 1 248 ? -5.842  -17.961 152.169 1.00 75.32  ? 267 MET F C   1 
ATOM   15770 O O   . MET F 1 248 ? -4.682  -18.037 151.744 1.00 73.70  ? 267 MET F O   1 
ATOM   15771 C CB  . MET F 1 248 ? -7.454  -16.652 150.785 1.00 78.24  ? 267 MET F CB  1 
ATOM   15772 C CG  . MET F 1 248 ? -7.678  -16.534 149.312 1.00 78.93  ? 267 MET F CG  1 
ATOM   15773 S SD  . MET F 1 248 ? -8.251  -14.907 148.818 1.00 81.41  ? 267 MET F SD  1 
ATOM   15774 C CE  . MET F 1 248 ? -9.500  -14.548 150.062 1.00 83.66  ? 267 MET F CE  1 
ATOM   15775 N N   . LEU F 1 249 ? -6.121  -17.765 153.459 1.00 73.52  ? 268 LEU F N   1 
ATOM   15776 C CA  . LEU F 1 249 ? -5.068  -17.755 154.472 1.00 73.04  ? 268 LEU F CA  1 
ATOM   15777 C C   . LEU F 1 249 ? -4.481  -19.154 154.666 1.00 71.68  ? 268 LEU F C   1 
ATOM   15778 O O   . LEU F 1 249 ? -3.258  -19.325 154.728 1.00 70.72  ? 268 LEU F O   1 
ATOM   15779 C CB  . LEU F 1 249 ? -5.638  -17.204 155.782 1.00 74.73  ? 268 LEU F CB  1 
ATOM   15780 C CG  . LEU F 1 249 ? -4.709  -16.997 156.972 1.00 74.72  ? 268 LEU F CG  1 
ATOM   15781 C CD1 . LEU F 1 249 ? -3.613  -16.029 156.625 1.00 73.80  ? 268 LEU F CD1 1 
ATOM   15782 C CD2 . LEU F 1 249 ? -5.520  -16.501 158.146 1.00 76.75  ? 268 LEU F CD2 1 
ATOM   15783 N N   . ARG F 1 250 ? -5.333  -20.175 154.757 1.00 73.73  ? 269 ARG F N   1 
ATOM   15784 C CA  . ARG F 1 250 ? -4.823  -21.531 154.932 1.00 72.90  ? 269 ARG F CA  1 
ATOM   15785 C C   . ARG F 1 250 ? -3.835  -21.873 153.828 1.00 71.23  ? 269 ARG F C   1 
ATOM   15786 O O   . ARG F 1 250 ? -2.821  -22.543 154.071 1.00 70.36  ? 269 ARG F O   1 
ATOM   15787 C CB  . ARG F 1 250 ? -5.975  -22.530 154.949 1.00 74.30  ? 269 ARG F CB  1 
ATOM   15788 C CG  . ARG F 1 250 ? -5.811  -23.653 155.947 1.00 74.46  ? 269 ARG F CG  1 
ATOM   15789 C CD  . ARG F 1 250 ? -7.104  -24.468 156.044 1.00 77.26  ? 269 ARG F CD  1 
ATOM   15790 N NE  . ARG F 1 250 ? -8.179  -23.655 156.603 1.00 77.90  ? 269 ARG F NE  1 
ATOM   15791 C CZ  . ARG F 1 250 ? -9.437  -23.646 156.182 1.00 79.44  ? 269 ARG F CZ  1 
ATOM   15792 N NH1 . ARG F 1 250 ? -9.852  -24.442 155.205 1.00 81.03  ? 269 ARG F NH1 1 
ATOM   15793 N NH2 . ARG F 1 250 ? -10.300 -22.814 156.755 1.00 79.28  ? 269 ARG F NH2 1 
ATOM   15794 N N   . ASP F 1 251 ? -4.117  -21.408 152.606 1.00 71.94  ? 270 ASP F N   1 
ATOM   15795 C CA  . ASP F 1 251 ? -3.240  -21.694 151.481 1.00 70.30  ? 270 ASP F CA  1 
ATOM   15796 C C   . ASP F 1 251 ? -1.947  -20.903 151.608 1.00 69.13  ? 270 ASP F C   1 
ATOM   15797 O O   . ASP F 1 251 ? -0.853  -21.448 151.429 1.00 67.70  ? 270 ASP F O   1 
ATOM   15798 C CB  . ASP F 1 251 ? -3.937  -21.386 150.149 1.00 71.00  ? 270 ASP F CB  1 
ATOM   15799 C CG  . ASP F 1 251 ? -5.000  -22.432 149.749 1.00 71.76  ? 270 ASP F CG  1 
ATOM   15800 O OD1 . ASP F 1 251 ? -5.078  -23.512 150.382 1.00 71.25  ? 270 ASP F OD1 1 
ATOM   15801 O OD2 . ASP F 1 251 ? -5.762  -22.172 148.782 1.00 73.26  ? 270 ASP F OD2 1 
ATOM   15802 N N   . ILE F 1 252 ? -2.052  -19.604 151.929 1.00 66.52  ? 271 ILE F N   1 
ATOM   15803 C CA  . ILE F 1 252 ? -0.854  -18.764 151.961 1.00 65.84  ? 271 ILE F CA  1 
ATOM   15804 C C   . ILE F 1 252 ? 0.130   -19.294 152.999 1.00 65.92  ? 271 ILE F C   1 
ATOM   15805 O O   . ILE F 1 252 ? 1.348   -19.280 152.777 1.00 64.98  ? 271 ILE F O   1 
ATOM   15806 C CB  . ILE F 1 252 ? -1.208  -17.289 152.227 1.00 67.05  ? 271 ILE F CB  1 
ATOM   15807 C CG1 . ILE F 1 252 ? -1.948  -16.656 151.046 1.00 67.91  ? 271 ILE F CG1 1 
ATOM   15808 C CG2 . ILE F 1 252 ? 0.057   -16.464 152.462 1.00 66.69  ? 271 ILE F CG2 1 
ATOM   15809 C CD1 . ILE F 1 252 ? -2.664  -15.370 151.388 1.00 69.92  ? 271 ILE F CD1 1 
ATOM   15810 N N   . LEU F 1 253 ? -0.377  -19.779 154.147 1.00 63.52  ? 272 LEU F N   1 
ATOM   15811 C CA  . LEU F 1 253 ? 0.522   -20.302 155.171 1.00 63.45  ? 272 LEU F CA  1 
ATOM   15812 C C   . LEU F 1 253 ? 1.078   -21.669 154.781 1.00 62.12  ? 272 LEU F C   1 
ATOM   15813 O O   . LEU F 1 253 ? 2.202   -22.014 155.158 1.00 61.81  ? 272 LEU F O   1 
ATOM   15814 C CB  . LEU F 1 253 ? -0.175  -20.402 156.524 1.00 65.33  ? 272 LEU F CB  1 
ATOM   15815 C CG  . LEU F 1 253 ? -0.428  -19.137 157.339 1.00 66.77  ? 272 LEU F CG  1 
ATOM   15816 C CD1 . LEU F 1 253 ? 0.719   -18.146 157.297 1.00 66.97  ? 272 LEU F CD1 1 
ATOM   15817 C CD2 . LEU F 1 253 ? -1.689  -18.511 156.838 1.00 67.04  ? 272 LEU F CD2 1 
ATOM   15818 N N   . GLU F 1 254 ? 0.315   -22.465 154.035 1.00 62.63  ? 273 GLU F N   1 
ATOM   15819 C CA  . GLU F 1 254 ? 0.831   -23.765 153.622 1.00 61.81  ? 273 GLU F CA  1 
ATOM   15820 C C   . GLU F 1 254 ? 1.893   -23.606 152.546 1.00 59.95  ? 273 GLU F C   1 
ATOM   15821 O O   . GLU F 1 254 ? 2.821   -24.411 152.454 1.00 59.15  ? 273 GLU F O   1 
ATOM   15822 C CB  . GLU F 1 254 ? -0.310  -24.647 153.158 1.00 62.56  ? 273 GLU F CB  1 
ATOM   15823 C CG  . GLU F 1 254 ? 0.132   -26.059 152.832 1.00 61.90  ? 273 GLU F CG  1 
ATOM   15824 C CD  . GLU F 1 254 ? 0.760   -26.804 154.013 1.00 62.73  ? 273 GLU F CD  1 
ATOM   15825 O OE1 . GLU F 1 254 ? 0.718   -26.297 155.160 1.00 63.82  ? 273 GLU F OE1 1 
ATOM   15826 O OE2 . GLU F 1 254 ? 1.311   -27.899 153.785 1.00 62.29  ? 273 GLU F OE2 1 
ATOM   15827 N N   . MET F 1 255 ? 1.814   -22.551 151.754 1.00 60.73  ? 274 MET F N   1 
ATOM   15828 C CA  . MET F 1 255 ? 2.954   -22.227 150.914 1.00 59.46  ? 274 MET F CA  1 
ATOM   15829 C C   . MET F 1 255 ? 4.151   -21.869 151.777 1.00 59.18  ? 274 MET F C   1 
ATOM   15830 O O   . MET F 1 255 ? 5.268   -22.343 151.543 1.00 58.29  ? 274 MET F O   1 
ATOM   15831 C CB  . MET F 1 255 ? 2.618   -21.076 149.972 1.00 59.65  ? 274 MET F CB  1 
ATOM   15832 C CG  . MET F 1 255 ? 3.760   -20.714 149.030 1.00 58.53  ? 274 MET F CG  1 
ATOM   15833 S SD  . MET F 1 255 ? 3.366   -19.396 147.846 1.00 59.34  ? 274 MET F SD  1 
ATOM   15834 C CE  . MET F 1 255 ? 2.811   -18.104 148.936 1.00 61.05  ? 274 MET F CE  1 
ATOM   15835 N N   . GLN F 1 256 ? 3.931   -21.020 152.786 1.00 57.57  ? 275 GLN F N   1 
ATOM   15836 C CA  . GLN F 1 256 ? 5.041   -20.520 153.601 1.00 58.33  ? 275 GLN F CA  1 
ATOM   15837 C C   . GLN F 1 256 ? 5.689   -21.666 154.370 1.00 58.31  ? 275 GLN F C   1 
ATOM   15838 O O   . GLN F 1 256 ? 6.918   -21.780 154.422 1.00 57.81  ? 275 GLN F O   1 
ATOM   15839 C CB  . GLN F 1 256 ? 4.543   -19.406 154.547 1.00 60.65  ? 275 GLN F CB  1 
ATOM   15840 C CG  . GLN F 1 256 ? 5.616   -18.787 155.505 1.00 61.80  ? 275 GLN F CG  1 
ATOM   15841 C CD  . GLN F 1 256 ? 5.089   -17.634 156.360 1.00 64.10  ? 275 GLN F CD  1 
ATOM   15842 O OE1 . GLN F 1 256 ? 5.627   -16.525 156.330 1.00 64.63  ? 275 GLN F OE1 1 
ATOM   15843 N NE2 . GLN F 1 256 ? 4.038   -17.892 157.121 1.00 64.95  ? 275 GLN F NE2 1 
ATOM   15844 N N   . ARG F 1 257 ? 4.869   -22.559 154.908 1.00 57.24  ? 276 ARG F N   1 
ATOM   15845 C CA  . ARG F 1 257 ? 5.377   -23.695 155.660 1.00 57.53  ? 276 ARG F CA  1 
ATOM   15846 C C   . ARG F 1 257 ? 6.116   -24.672 154.756 1.00 55.51  ? 276 ARG F C   1 
ATOM   15847 O O   . ARG F 1 257 ? 7.268   -25.022 155.029 1.00 54.77  ? 276 ARG F O   1 
ATOM   15848 C CB  . ARG F 1 257 ? 4.208   -24.359 156.376 1.00 59.43  ? 276 ARG F CB  1 
ATOM   15849 C CG  . ARG F 1 257 ? 4.597   -25.369 157.388 1.00 60.01  ? 276 ARG F CG  1 
ATOM   15850 C CD  . ARG F 1 257 ? 3.438   -26.336 157.611 1.00 61.23  ? 276 ARG F CD  1 
ATOM   15851 N NE  . ARG F 1 257 ? 3.184   -27.177 156.449 1.00 60.26  ? 276 ARG F NE  1 
ATOM   15852 C CZ  . ARG F 1 257 ? 3.961   -28.183 156.075 1.00 58.93  ? 276 ARG F CZ  1 
ATOM   15853 N NH1 . ARG F 1 257 ? 5.077   -28.458 156.719 1.00 58.67  ? 276 ARG F NH1 1 
ATOM   15854 N NH2 . ARG F 1 257 ? 3.604   -28.931 155.031 1.00 58.26  ? 276 ARG F NH2 1 
ATOM   15855 N N   . ALA F 1 258 ? 5.484   -25.096 153.652 1.00 56.06  ? 277 ALA F N   1 
ATOM   15856 C CA  . ALA F 1 258 ? 6.049   -26.174 152.850 1.00 54.47  ? 277 ALA F CA  1 
ATOM   15857 C C   . ALA F 1 258 ? 7.286   -25.735 152.082 1.00 52.57  ? 277 ALA F C   1 
ATOM   15858 O O   . ALA F 1 258 ? 8.205   -26.528 151.885 1.00 50.92  ? 277 ALA F O   1 
ATOM   15859 C CB  . ALA F 1 258 ? 5.000   -26.713 151.891 1.00 54.47  ? 277 ALA F CB  1 
ATOM   15860 N N   . ALA F 1 259 ? 7.330   -24.491 151.623 1.00 53.32  ? 278 ALA F N   1 
ATOM   15861 C CA  . ALA F 1 259 ? 8.541   -24.005 150.961 1.00 52.30  ? 278 ALA F CA  1 
ATOM   15862 C C   . ALA F 1 259 ? 9.644   -23.681 151.966 1.00 51.91  ? 278 ALA F C   1 
ATOM   15863 O O   . ALA F 1 259 ? 10.825  -23.835 151.654 1.00 48.28  ? 278 ALA F O   1 
ATOM   15864 C CB  . ALA F 1 259 ? 8.233   -22.774 150.108 1.00 52.70  ? 278 ALA F CB  1 
ATOM   15865 N N   . LYS F 1 260 ? 9.280   -23.237 153.169 1.00 53.89  ? 279 LYS F N   1 
ATOM   15866 C CA  . LYS F 1 260 ? 10.266  -23.123 154.237 1.00 52.93  ? 279 LYS F CA  1 
ATOM   15867 C C   . LYS F 1 260 ? 10.836  -24.486 154.594 1.00 49.53  ? 279 LYS F C   1 
ATOM   15868 O O   . LYS F 1 260 ? 11.979  -24.581 155.057 1.00 46.25  ? 279 LYS F O   1 
ATOM   15869 C CB  . LYS F 1 260 ? 9.644   -22.498 155.487 1.00 57.37  ? 279 LYS F CB  1 
ATOM   15870 C CG  . LYS F 1 260 ? 9.745   -21.003 155.565 1.00 59.15  ? 279 LYS F CG  1 
ATOM   15871 C CD  . LYS F 1 260 ? 8.956   -20.481 156.740 1.00 62.56  ? 279 LYS F CD  1 
ATOM   15872 C CE  . LYS F 1 260 ? 9.107   -18.971 156.848 1.00 64.32  ? 279 LYS F CE  1 
ATOM   15873 N NZ  . LYS F 1 260 ? 10.506  -18.467 156.609 1.00 62.71  ? 279 LYS F NZ  1 
ATOM   15874 N N   . ALA F 1 261 ? 10.044  -25.549 154.414 1.00 53.93  ? 280 ALA F N   1 
ATOM   15875 C CA  . ALA F 1 261 ? 10.481  -26.918 154.656 1.00 51.03  ? 280 ALA F CA  1 
ATOM   15876 C C   . ALA F 1 261 ? 11.284  -27.490 153.507 1.00 46.61  ? 280 ALA F C   1 
ATOM   15877 O O   . ALA F 1 261 ? 11.646  -28.658 153.577 1.00 44.54  ? 280 ALA F O   1 
ATOM   15878 C CB  . ALA F 1 261 ? 9.279   -27.827 154.923 1.00 54.71  ? 280 ALA F CB  1 
ATOM   15879 N N   . GLY F 1 262 ? 11.534  -26.733 152.444 1.00 51.69  ? 281 GLY F N   1 
ATOM   15880 C CA  . GLY F 1 262 ? 12.374  -27.186 151.352 1.00 46.99  ? 281 GLY F CA  1 
ATOM   15881 C C   . GLY F 1 262 ? 11.671  -27.727 150.120 1.00 47.21  ? 281 GLY F C   1 
ATOM   15882 O O   . GLY F 1 262 ? 12.354  -28.223 149.214 1.00 45.09  ? 281 GLY F O   1 
ATOM   15883 N N   . LYS F 1 263 ? 10.344  -27.646 150.059 1.00 48.99  ? 282 LYS F N   1 
ATOM   15884 C CA  . LYS F 1 263 ? 9.563   -28.056 148.907 1.00 49.38  ? 282 LYS F CA  1 
ATOM   15885 C C   . LYS F 1 263 ? 9.314   -26.892 147.949 1.00 50.06  ? 282 LYS F C   1 
ATOM   15886 O O   . LYS F 1 263 ? 9.299   -25.721 148.338 1.00 51.94  ? 282 LYS F O   1 
ATOM   15887 C CB  . LYS F 1 263 ? 8.190   -28.589 149.330 1.00 53.61  ? 282 LYS F CB  1 
ATOM   15888 C CG  . LYS F 1 263 ? 8.206   -29.822 150.141 1.00 54.29  ? 282 LYS F CG  1 
ATOM   15889 C CD  . LYS F 1 263 ? 9.005   -30.849 149.407 1.00 50.09  ? 282 LYS F CD  1 
ATOM   15890 C CE  . LYS F 1 263 ? 8.882   -32.200 150.040 1.00 50.54  ? 282 LYS F CE  1 
ATOM   15891 N NZ  . LYS F 1 263 ? 9.848   -33.099 149.359 1.00 47.19  ? 282 LYS F NZ  1 
ATOM   15892 N N   . ILE F 1 264 ? 9.047   -27.245 146.691 1.00 48.81  ? 283 ILE F N   1 
ATOM   15893 C CA  . ILE F 1 264 ? 8.531   -26.301 145.708 1.00 49.76  ? 283 ILE F CA  1 
ATOM   15894 C C   . ILE F 1 264 ? 7.030   -26.139 145.885 1.00 53.75  ? 283 ILE F C   1 
ATOM   15895 O O   . ILE F 1 264 ? 6.318   -27.105 146.171 1.00 55.28  ? 283 ILE F O   1 
ATOM   15896 C CB  . ILE F 1 264 ? 8.860   -26.809 144.299 1.00 47.12  ? 283 ILE F CB  1 
ATOM   15897 C CG1 . ILE F 1 264 ? 10.365  -26.916 144.091 1.00 44.29  ? 283 ILE F CG1 1 
ATOM   15898 C CG2 . ILE F 1 264 ? 8.212   -25.905 143.275 1.00 48.74  ? 283 ILE F CG2 1 
ATOM   15899 C CD1 . ILE F 1 264 ? 10.726  -27.806 142.910 1.00 44.28  ? 283 ILE F CD1 1 
ATOM   15900 N N   . VAL F 1 265 ? 6.533   -24.921 145.712 1.00 50.67  ? 284 VAL F N   1 
ATOM   15901 C CA  . VAL F 1 265 ? 5.096   -24.681 145.661 1.00 53.24  ? 284 VAL F CA  1 
ATOM   15902 C C   . VAL F 1 265 ? 4.772   -23.905 144.388 1.00 53.88  ? 284 VAL F C   1 
ATOM   15903 O O   . VAL F 1 265 ? 5.521   -23.020 143.985 1.00 53.00  ? 284 VAL F O   1 
ATOM   15904 C CB  . VAL F 1 265 ? 4.571   -23.918 146.890 1.00 54.60  ? 284 VAL F CB  1 
ATOM   15905 C CG1 . VAL F 1 265 ? 3.051   -23.723 146.780 1.00 56.23  ? 284 VAL F CG1 1 
ATOM   15906 C CG2 . VAL F 1 265 ? 4.946   -24.660 148.157 1.00 54.86  ? 284 VAL F CG2 1 
ATOM   15907 N N   . VAL F 1 266 ? 3.688   -24.277 143.724 1.00 56.95  ? 285 VAL F N   1 
ATOM   15908 C CA  . VAL F 1 266 ? 3.201   -23.553 142.566 1.00 57.50  ? 285 VAL F CA  1 
ATOM   15909 C C   . VAL F 1 266 ? 1.830   -23.031 142.934 1.00 59.77  ? 285 VAL F C   1 
ATOM   15910 O O   . VAL F 1 266 ? 0.950   -23.808 143.314 1.00 60.54  ? 285 VAL F O   1 
ATOM   15911 C CB  . VAL F 1 266 ? 3.140   -24.415 141.295 1.00 55.92  ? 285 VAL F CB  1 
ATOM   15912 C CG1 . VAL F 1 266 ? 2.789   -23.504 140.098 1.00 56.48  ? 285 VAL F CG1 1 
ATOM   15913 C CG2 . VAL F 1 266 ? 4.448   -25.136 141.039 1.00 52.27  ? 285 VAL F CG2 1 
ATOM   15914 N N   . LEU F 1 267 ? 1.658   -21.725 142.863 1.00 58.97  ? 286 LEU F N   1 
ATOM   15915 C CA  . LEU F 1 267 ? 0.393   -21.096 143.198 1.00 60.82  ? 286 LEU F CA  1 
ATOM   15916 C C   . LEU F 1 267 ? -0.276  -20.645 141.908 1.00 62.50  ? 286 LEU F C   1 
ATOM   15917 O O   . LEU F 1 267 ? 0.267   -19.796 141.201 1.00 62.20  ? 286 LEU F O   1 
ATOM   15918 C CB  . LEU F 1 267 ? 0.625   -19.912 144.126 1.00 60.92  ? 286 LEU F CB  1 
ATOM   15919 C CG  . LEU F 1 267 ? -0.612  -19.252 144.734 1.00 62.85  ? 286 LEU F CG  1 
ATOM   15920 C CD1 . LEU F 1 267 ? -0.148  -18.597 146.046 1.00 62.79  ? 286 LEU F CD1 1 
ATOM   15921 C CD2 . LEU F 1 267 ? -1.295  -18.220 143.829 1.00 64.95  ? 286 LEU F CD2 1 
ATOM   15922 N N   . LYS F 1 268 ? -1.444  -21.193 141.598 1.00 63.82  ? 287 LYS F N   1 
ATOM   15923 C CA  . LYS F 1 268 ? -2.140  -20.821 140.370 1.00 65.75  ? 287 LYS F CA  1 
ATOM   15924 C C   . LYS F 1 268 ? -3.050  -19.636 140.648 1.00 68.48  ? 287 LYS F C   1 
ATOM   15925 O O   . LYS F 1 268 ? -4.087  -19.781 141.304 1.00 69.54  ? 287 LYS F O   1 
ATOM   15926 C CB  . LYS F 1 268 ? -2.941  -21.982 139.782 1.00 65.91  ? 287 LYS F CB  1 
ATOM   15927 C CG  . LYS F 1 268 ? -3.823  -21.581 138.619 1.00 68.37  ? 287 LYS F CG  1 
ATOM   15928 C CD  . LYS F 1 268 ? -3.036  -21.101 137.404 1.00 65.29  ? 287 LYS F CD  1 
ATOM   15929 C CE  . LYS F 1 268 ? -3.966  -20.999 136.181 1.00 66.94  ? 287 LYS F CE  1 
ATOM   15930 N NZ  . LYS F 1 268 ? -3.732  -22.041 135.106 1.00 64.81  ? 287 LYS F NZ  1 
ATOM   15931 N N   . GLY F 1 269 ? -2.649  -18.471 140.176 1.00 67.91  ? 288 GLY F N   1 
ATOM   15932 C CA  . GLY F 1 269 ? -3.515  -17.324 140.226 1.00 69.84  ? 288 GLY F CA  1 
ATOM   15933 C C   . GLY F 1 269 ? -4.486  -17.324 139.063 1.00 70.66  ? 288 GLY F C   1 
ATOM   15934 O O   . GLY F 1 269 ? -4.189  -17.781 137.956 1.00 68.99  ? 288 GLY F O   1 
ATOM   15935 N N   . TRP F 1 270 ? -5.671  -16.795 139.326 1.00 72.89  ? 289 TRP F N   1 
ATOM   15936 C CA  . TRP F 1 270 ? -6.722  -16.736 138.329 1.00 73.68  ? 289 TRP F CA  1 
ATOM   15937 C C   . TRP F 1 270 ? -7.070  -15.297 138.042 1.00 74.72  ? 289 TRP F C   1 
ATOM   15938 O O   . TRP F 1 270 ? -7.254  -14.505 138.972 1.00 76.62  ? 289 TRP F O   1 
ATOM   15939 C CB  . TRP F 1 270 ? -7.964  -17.484 138.800 1.00 75.43  ? 289 TRP F CB  1 
ATOM   15940 C CG  . TRP F 1 270 ? -7.734  -18.920 138.908 1.00 73.80  ? 289 TRP F CG  1 
ATOM   15941 C CD1 . TRP F 1 270 ? -7.443  -19.600 140.038 1.00 72.81  ? 289 TRP F CD1 1 
ATOM   15942 C CD2 . TRP F 1 270 ? -7.762  -19.884 137.847 1.00 72.58  ? 289 TRP F CD2 1 
ATOM   15943 N NE1 . TRP F 1 270 ? -7.294  -20.936 139.759 1.00 71.75  ? 289 TRP F NE1 1 
ATOM   15944 C CE2 . TRP F 1 270 ? -7.477  -21.134 138.417 1.00 71.77  ? 289 TRP F CE2 1 
ATOM   15945 C CE3 . TRP F 1 270 ? -7.995  -19.812 136.471 1.00 72.46  ? 289 TRP F CE3 1 
ATOM   15946 C CZ2 . TRP F 1 270 ? -7.422  -22.299 137.665 1.00 70.92  ? 289 TRP F CZ2 1 
ATOM   15947 C CZ3 . TRP F 1 270 ? -7.946  -20.978 135.726 1.00 71.54  ? 289 TRP F CZ3 1 
ATOM   15948 C CH2 . TRP F 1 270 ? -7.666  -22.197 136.323 1.00 70.89  ? 289 TRP F CH2 1 
ATOM   15949 N N   . ALA F 1 271 ? -7.188  -14.974 136.761 1.00 75.25  ? 290 ALA F N   1 
ATOM   15950 C CA  . ALA F 1 271 ? -7.200  -13.586 136.317 1.00 76.18  ? 290 ALA F CA  1 
ATOM   15951 C C   . ALA F 1 271 ? -8.642  -13.055 136.301 1.00 78.85  ? 290 ALA F C   1 
ATOM   15952 O O   . ALA F 1 271 ? -9.169  -12.629 135.277 1.00 79.46  ? 290 ALA F O   1 
ATOM   15953 C CB  . ALA F 1 271 ? -6.556  -13.471 134.943 1.00 74.68  ? 290 ALA F CB  1 
ATOM   15954 N N   . GLY F 1 272 ? -9.266  -13.088 137.481 1.00 78.55  ? 291 GLY F N   1 
ATOM   15955 C CA  . GLY F 1 272 ? -10.580 -12.492 137.655 1.00 81.11  ? 291 GLY F CA  1 
ATOM   15956 C C   . GLY F 1 272 ? -11.740 -13.287 137.102 1.00 82.03  ? 291 GLY F C   1 
ATOM   15957 O O   . GLY F 1 272 ? -12.873 -12.794 137.130 1.00 84.46  ? 291 GLY F O   1 
ATOM   15958 N N   . PHE F 1 273 ? -11.496 -14.487 136.591 1.00 82.30  ? 292 PHE F N   1 
ATOM   15959 C CA  . PHE F 1 273 ? -12.516 -15.403 136.094 1.00 82.79  ? 292 PHE F CA  1 
ATOM   15960 C C   . PHE F 1 273 ? -11.741 -16.671 135.741 1.00 80.68  ? 292 PHE F C   1 
ATOM   15961 O O   . PHE F 1 273 ? -10.502 -16.670 135.714 1.00 78.79  ? 292 PHE F O   1 
ATOM   15962 C CB  . PHE F 1 273 ? -13.319 -14.828 134.922 1.00 84.64  ? 292 PHE F CB  1 
ATOM   15963 C CG  . PHE F 1 273 ? -12.497 -14.526 133.708 1.00 84.02  ? 292 PHE F CG  1 
ATOM   15964 C CD1 . PHE F 1 273 ? -11.655 -13.430 133.673 1.00 82.62  ? 292 PHE F CD1 1 
ATOM   15965 C CD2 . PHE F 1 273 ? -12.562 -15.344 132.596 1.00 85.23  ? 292 PHE F CD2 1 
ATOM   15966 C CE1 . PHE F 1 273 ? -10.886 -13.175 132.559 1.00 82.64  ? 292 PHE F CE1 1 
ATOM   15967 C CE2 . PHE F 1 273 ? -11.801 -15.084 131.470 1.00 85.24  ? 292 PHE F CE2 1 
ATOM   15968 C CZ  . PHE F 1 273 ? -10.966 -14.006 131.452 1.00 83.97  ? 292 PHE F CZ  1 
ATOM   15969 N N   . THR F 1 274 ? -12.477 -17.765 135.534 1.00 82.22  ? 293 THR F N   1 
ATOM   15970 C CA  . THR F 1 274 ? -11.881 -19.061 135.223 1.00 81.15  ? 293 THR F CA  1 
ATOM   15971 C C   . THR F 1 274 ? -12.439 -19.560 133.898 1.00 83.82  ? 293 THR F C   1 
ATOM   15972 O O   . THR F 1 274 ? -13.391 -19.002 133.351 1.00 86.43  ? 293 THR F O   1 
ATOM   15973 C CB  . THR F 1 274 ? -12.131 -20.092 136.338 1.00 81.02  ? 293 THR F CB  1 
ATOM   15974 O OG1 . THR F 1 274 ? -13.478 -20.577 136.279 1.00 83.93  ? 293 THR F OG1 1 
ATOM   15975 C CG2 . THR F 1 274 ? -11.875 -19.470 137.705 1.00 80.41  ? 293 THR F CG2 1 
ATOM   15976 N N   . PHE F 1 275 ? -11.828 -20.628 133.379 1.00 83.32  ? 294 PHE F N   1 
ATOM   15977 C CA  . PHE F 1 275 ? -12.266 -21.171 132.094 1.00 86.08  ? 294 PHE F CA  1 
ATOM   15978 C C   . PHE F 1 275 ? -13.634 -21.842 132.166 1.00 89.12  ? 294 PHE F C   1 
ATOM   15979 O O   . PHE F 1 275 ? -14.169 -22.229 131.119 1.00 92.44  ? 294 PHE F O   1 
ATOM   15980 C CB  . PHE F 1 275 ? -11.225 -22.169 131.556 1.00 85.06  ? 294 PHE F CB  1 
ATOM   15981 C CG  . PHE F 1 275 ? -11.139 -23.483 132.324 1.00 84.31  ? 294 PHE F CG  1 
ATOM   15982 C CD1 . PHE F 1 275 ? -11.004 -23.514 133.714 1.00 82.67  ? 294 PHE F CD1 1 
ATOM   15983 C CD2 . PHE F 1 275 ? -11.145 -24.680 131.631 1.00 85.93  ? 294 PHE F CD2 1 
ATOM   15984 C CE1 . PHE F 1 275 ? -10.908 -24.711 134.391 1.00 82.09  ? 294 PHE F CE1 1 
ATOM   15985 C CE2 . PHE F 1 275 ? -11.049 -25.869 132.290 1.00 85.46  ? 294 PHE F CE2 1 
ATOM   15986 C CZ  . PHE F 1 275 ? -10.930 -25.894 133.675 1.00 83.50  ? 294 PHE F CZ  1 
ATOM   15987 N N   . ILE F 1 276 ? -14.225 -21.953 133.353 1.00 87.44  ? 295 ILE F N   1 
ATOM   15988 C CA  . ILE F 1 276 ? -15.543 -22.550 133.512 1.00 90.67  ? 295 ILE F CA  1 
ATOM   15989 C C   . ILE F 1 276 ? -16.617 -21.496 133.804 1.00 92.57  ? 295 ILE F C   1 
ATOM   15990 O O   . ILE F 1 276 ? -17.676 -21.822 134.334 1.00 94.72  ? 295 ILE F O   1 
ATOM   15991 C CB  . ILE F 1 276 ? -15.516 -23.652 134.586 1.00 89.95  ? 295 ILE F CB  1 
ATOM   15992 C CG1 . ILE F 1 276 ? -14.981 -23.170 135.951 1.00 87.45  ? 295 ILE F CG1 1 
ATOM   15993 C CG2 . ILE F 1 276 ? -14.583 -24.788 134.137 1.00 88.45  ? 295 ILE F CG2 1 
ATOM   15994 C CD1 . ILE F 1 276 ? -15.878 -22.175 136.690 1.00 87.85  ? 295 ILE F CD1 1 
ATOM   15995 N N   . ASP F 1 277 ? -16.372 -20.234 133.444 1.00 92.09  ? 296 ASP F N   1 
ATOM   15996 C CA  . ASP F 1 277 ? -17.259 -19.151 133.851 1.00 93.64  ? 296 ASP F CA  1 
ATOM   15997 C C   . ASP F 1 277 ? -18.083 -18.620 132.685 1.00 96.66  ? 296 ASP F C   1 
ATOM   15998 O O   . ASP F 1 277 ? -17.996 -17.423 132.378 1.00 96.21  ? 296 ASP F O   1 
ATOM   15999 C CB  . ASP F 1 277 ? -16.477 -17.956 134.430 1.00 90.72  ? 296 ASP F CB  1 
ATOM   16000 N N   . ASP F 1 278 ? -18.879 -19.488 132.050 1.00 99.87  ? 297 ASP F N   1 
ATOM   16001 C CA  . ASP F 1 278 ? -19.605 -19.162 130.825 1.00 102.86 ? 297 ASP F CA  1 
ATOM   16002 C C   . ASP F 1 278 ? -19.721 -17.659 130.615 1.00 103.40 ? 297 ASP F C   1 
ATOM   16003 O O   . ASP F 1 278 ? -19.119 -17.124 129.677 1.00 103.39 ? 297 ASP F O   1 
ATOM   16004 C CB  . ASP F 1 278 ? -20.998 -19.804 130.836 1.00 106.91 ? 297 ASP F CB  1 
ATOM   16005 N N   . GLN F 1 279 ? -20.430 -16.960 131.519 1.00 103.98 ? 298 GLN F N   1 
ATOM   16006 C CA  . GLN F 1 279 ? -20.740 -15.544 131.302 1.00 105.04 ? 298 GLN F CA  1 
ATOM   16007 C C   . GLN F 1 279 ? -19.486 -14.674 131.303 1.00 101.86 ? 298 GLN F C   1 
ATOM   16008 O O   . GLN F 1 279 ? -19.445 -13.661 130.600 1.00 102.80 ? 298 GLN F O   1 
ATOM   16009 C CB  . GLN F 1 279 ? -21.725 -15.034 132.362 1.00 106.19 ? 298 GLN F CB  1 
ATOM   16010 N N   . ALA F 1 280 ? -18.463 -15.035 132.083 1.00 99.61  ? 299 ALA F N   1 
ATOM   16011 C CA  . ALA F 1 280 ? -17.204 -14.298 132.027 1.00 96.55  ? 299 ALA F CA  1 
ATOM   16012 C C   . ALA F 1 280 ? -16.389 -14.700 130.803 1.00 95.98  ? 299 ALA F C   1 
ATOM   16013 O O   . ALA F 1 280 ? -15.716 -13.863 130.188 1.00 95.48  ? 299 ALA F O   1 
ATOM   16014 C CB  . ALA F 1 280 ? -16.398 -14.531 133.304 1.00 92.94  ? 299 ALA F CB  1 
ATOM   16015 N N   . MET F 1 281 ? -16.438 -15.985 130.446 1.00 95.88  ? 300 MET F N   1 
ATOM   16016 C CA  . MET F 1 281 ? -15.731 -16.475 129.274 1.00 95.86  ? 300 MET F CA  1 
ATOM   16017 C C   . MET F 1 281 ? -16.321 -15.939 127.993 1.00 99.12  ? 300 MET F C   1 
ATOM   16018 O O   . MET F 1 281 ? -15.624 -15.902 126.977 1.00 99.53  ? 300 MET F O   1 
ATOM   16019 C CB  . MET F 1 281 ? -15.769 -17.999 129.240 1.00 95.96  ? 300 MET F CB  1 
ATOM   16020 C CG  . MET F 1 281 ? -14.923 -18.638 130.317 1.00 92.56  ? 300 MET F CG  1 
ATOM   16021 S SD  . MET F 1 281 ? -13.164 -18.353 130.005 1.00 89.13  ? 300 MET F SD  1 
ATOM   16022 C CE  . MET F 1 281 ? -12.903 -19.400 128.566 1.00 91.58  ? 300 MET F CE  1 
ATOM   16023 N N   . ARG F 1 282 ? -17.584 -15.538 128.026 1.00 101.34 ? 301 ARG F N   1 
ATOM   16024 C CA  . ARG F 1 282 ? -18.284 -14.989 126.870 1.00 104.78 ? 301 ARG F CA  1 
ATOM   16025 C C   . ARG F 1 282 ? -17.989 -13.506 126.656 1.00 104.58 ? 301 ARG F C   1 
ATOM   16026 O O   . ARG F 1 282 ? -18.906 -12.726 126.394 1.00 107.31 ? 301 ARG F O   1 
ATOM   16027 C CB  . ARG F 1 282 ? -19.781 -15.234 127.062 1.00 108.31 ? 301 ARG F CB  1 
ATOM   16028 N N   . LYS F 1 283 ? -16.719 -13.090 126.779 1.00 101.54 ? 302 LYS F N   1 
ATOM   16029 C CA  . LYS F 1 283 ? -16.298 -11.705 126.609 1.00 101.28 ? 302 LYS F CA  1 
ATOM   16030 C C   . LYS F 1 283 ? -15.241 -11.617 125.518 1.00 100.70 ? 302 LYS F C   1 
ATOM   16031 O O   . LYS F 1 283 ? -14.414 -12.529 125.385 1.00 98.89  ? 302 LYS F O   1 
ATOM   16032 C CB  . LYS F 1 283 ? -15.724 -11.126 127.915 1.00 98.27  ? 302 LYS F CB  1 
ATOM   16033 N N   . PRO F 1 284 ? -15.270 -10.557 124.686 1.00 102.36 ? 303 PRO F N   1 
ATOM   16034 C CA  . PRO F 1 284 ? -14.195 -10.362 123.704 1.00 101.91 ? 303 PRO F CA  1 
ATOM   16035 C C   . PRO F 1 284 ? -12.809 -10.502 124.308 1.00 97.94  ? 303 PRO F C   1 
ATOM   16036 O O   . PRO F 1 284 ? -12.629 -10.314 125.520 1.00 95.74  ? 303 PRO F O   1 
ATOM   16037 C CB  . PRO F 1 284 ? -14.441 -8.935  123.186 1.00 103.93 ? 303 PRO F CB  1 
ATOM   16038 C CG  . PRO F 1 284 ? -15.885 -8.697  123.388 1.00 106.26 ? 303 PRO F CG  1 
ATOM   16039 C CD  . PRO F 1 284 ? -16.400 -9.640  124.461 1.00 105.63 ? 303 PRO F CD  1 
ATOM   16040 N N   . LEU F 1 285 ? -11.821 -10.830 123.478 1.00 97.14  ? 304 LEU F N   1 
ATOM   16041 C CA  . LEU F 1 285 ? -10.458 -10.945 123.965 1.00 93.58  ? 304 LEU F CA  1 
ATOM   16042 C C   . LEU F 1 285 ? -9.948  -9.626  124.525 1.00 92.31  ? 304 LEU F C   1 
ATOM   16043 O O   . LEU F 1 285 ? -9.161  -9.624  125.480 1.00 89.38  ? 304 LEU F O   1 
ATOM   16044 C CB  . LEU F 1 285 ? -9.546  -11.438 122.841 1.00 93.55  ? 304 LEU F CB  1 
ATOM   16045 C CG  . LEU F 1 285 ? -8.068  -11.612 123.225 1.00 90.14  ? 304 LEU F CG  1 
ATOM   16046 C CD1 . LEU F 1 285 ? -7.886  -12.536 124.450 1.00 87.26  ? 304 LEU F CD1 1 
ATOM   16047 C CD2 . LEU F 1 285 ? -7.246  -12.111 122.024 1.00 90.42  ? 304 LEU F CD2 1 
ATOM   16048 N N   . THR F 1 286 ? -10.379 -8.500  123.956 1.00 94.62  ? 305 THR F N   1 
ATOM   16049 C CA  . THR F 1 286 ? -10.004 -7.209  124.523 1.00 93.70  ? 305 THR F CA  1 
ATOM   16050 C C   . THR F 1 286 ? -10.506 -7.090  125.959 1.00 92.50  ? 305 THR F C   1 
ATOM   16051 O O   . THR F 1 286 ? -9.845  -6.496  126.816 1.00 90.44  ? 305 THR F O   1 
ATOM   16052 C CB  . THR F 1 286 ? -10.563 -6.060  123.663 1.00 96.88  ? 305 THR F CB  1 
ATOM   16053 O OG1 . THR F 1 286 ? -10.031 -6.121  122.331 1.00 97.95  ? 305 THR F OG1 1 
ATOM   16054 C CG2 . THR F 1 286 ? -10.215 -4.700  124.271 1.00 96.21  ? 305 THR F CG2 1 
ATOM   16055 N N   . GLN F 1 287 ? -11.681 -7.648  126.232 1.00 94.08  ? 306 GLN F N   1 
ATOM   16056 C CA  . GLN F 1 287 ? -12.301 -7.555  127.548 1.00 93.24  ? 306 GLN F CA  1 
ATOM   16057 C C   . GLN F 1 287 ? -11.711 -8.551  128.539 1.00 90.04  ? 306 GLN F C   1 
ATOM   16058 O O   . GLN F 1 287 ? -11.614 -8.255  129.740 1.00 88.24  ? 306 GLN F O   1 
ATOM   16059 C CB  . GLN F 1 287 ? -13.806 -7.782  127.377 1.00 96.45  ? 306 GLN F CB  1 
ATOM   16060 C CG  . GLN F 1 287 ? -14.588 -7.791  128.653 1.00 95.94  ? 306 GLN F CG  1 
ATOM   16061 C CD  . GLN F 1 287 ? -14.429 -6.494  129.406 1.00 94.82  ? 306 GLN F CD  1 
ATOM   16062 O OE1 . GLN F 1 287 ? -13.340 -6.189  129.910 1.00 92.05  ? 306 GLN F OE1 1 
ATOM   16063 N NE2 . GLN F 1 287 ? -15.505 -5.712  129.478 1.00 97.00  ? 306 GLN F NE2 1 
ATOM   16064 N N   . LYS F 1 288 ? -11.320 -9.728  128.066 1.00 89.48  ? 307 LYS F N   1 
ATOM   16065 C CA  . LYS F 1 288 ? -10.622 -10.659 128.934 1.00 86.36  ? 307 LYS F CA  1 
ATOM   16066 C C   . LYS F 1 288 ? -9.285  -10.082 129.373 1.00 83.64  ? 307 LYS F C   1 
ATOM   16067 O O   . LYS F 1 288 ? -8.832  -10.348 130.494 1.00 81.19  ? 307 LYS F O   1 
ATOM   16068 C CB  . LYS F 1 288 ? -10.457 -11.997 128.206 1.00 86.37  ? 307 LYS F CB  1 
ATOM   16069 C CG  . LYS F 1 288 ? -11.745 -12.861 128.212 1.00 88.88  ? 307 LYS F CG  1 
ATOM   16070 C CD  . LYS F 1 288 ? -12.043 -13.570 126.886 1.00 91.29  ? 307 LYS F CD  1 
ATOM   16071 C CE  . LYS F 1 288 ? -10.835 -14.300 126.332 1.00 89.49  ? 307 LYS F CE  1 
ATOM   16072 N NZ  . LYS F 1 288 ? -11.177 -15.013 125.069 1.00 91.97  ? 307 LYS F NZ  1 
ATOM   16073 N N   . ARG F 1 289 ? -8.649  -9.270  128.533 1.00 84.07  ? 308 ARG F N   1 
ATOM   16074 C CA  . ARG F 1 289 ? -7.399  -8.649  128.943 1.00 81.77  ? 308 ARG F CA  1 
ATOM   16075 C C   . ARG F 1 289 ? -7.653  -7.576  129.992 1.00 81.43  ? 308 ARG F C   1 
ATOM   16076 O O   . ARG F 1 289 ? -6.980  -7.538  131.023 1.00 78.98  ? 308 ARG F O   1 
ATOM   16077 C CB  . ARG F 1 289 ? -6.666  -8.091  127.721 1.00 82.90  ? 308 ARG F CB  1 
ATOM   16078 C CG  . ARG F 1 289 ? -5.801  -9.154  127.082 1.00 83.03  ? 308 ARG F CG  1 
ATOM   16079 C CD  . ARG F 1 289 ? -5.377  -8.867  125.674 1.00 83.81  ? 308 ARG F CD  1 
ATOM   16080 N NE  . ARG F 1 289 ? -5.235  -10.128 124.952 1.00 83.48  ? 308 ARG F NE  1 
ATOM   16081 C CZ  . ARG F 1 289 ? -4.565  -10.287 123.818 1.00 85.01  ? 308 ARG F CZ  1 
ATOM   16082 N NH1 . ARG F 1 289 ? -3.970  -9.266  123.215 1.00 86.96  ? 308 ARG F NH1 1 
ATOM   16083 N NH2 . ARG F 1 289 ? -4.491  -11.501 123.274 1.00 85.08  ? 308 ARG F NH2 1 
ATOM   16084 N N   . ARG F 1 290 ? -8.633  -6.701  129.755 1.00 83.85  ? 309 ARG F N   1 
ATOM   16085 C CA  . ARG F 1 290 ? -8.893  -5.623  130.708 1.00 83.89  ? 309 ARG F CA  1 
ATOM   16086 C C   . ARG F 1 290 ? -9.132  -6.178  132.111 1.00 82.20  ? 309 ARG F C   1 
ATOM   16087 O O   . ARG F 1 290 ? -8.628  -5.625  133.096 1.00 80.67  ? 309 ARG F O   1 
ATOM   16088 C CB  . ARG F 1 290 ? -10.087 -4.775  130.250 1.00 87.30  ? 309 ARG F CB  1 
ATOM   16089 N N   . VAL F 1 291 ? -9.903  -7.270  132.221 1.00 82.78  ? 310 VAL F N   1 
ATOM   16090 C CA  . VAL F 1 291 ? -10.248 -7.805  133.537 1.00 81.35  ? 310 VAL F CA  1 
ATOM   16091 C C   . VAL F 1 291 ? -9.036  -8.450  134.169 1.00 78.10  ? 310 VAL F C   1 
ATOM   16092 O O   . VAL F 1 291 ? -8.824  -8.364  135.383 1.00 77.99  ? 310 VAL F O   1 
ATOM   16093 C CB  . VAL F 1 291 ? -11.404 -8.816  133.440 1.00 82.88  ? 310 VAL F CB  1 
ATOM   16094 C CG1 . VAL F 1 291 ? -11.037 -9.944  132.486 1.00 82.56  ? 310 VAL F CG1 1 
ATOM   16095 C CG2 . VAL F 1 291 ? -11.731 -9.376  134.818 1.00 81.70  ? 310 VAL F CG2 1 
ATOM   16096 N N   . ALA F 1 292 ? -8.240  -9.133  133.353 1.00 79.28  ? 311 ALA F N   1 
ATOM   16097 C CA  . ALA F 1 292 ? -7.033  -9.767  133.852 1.00 77.15  ? 311 ALA F CA  1 
ATOM   16098 C C   . ALA F 1 292 ? -6.053  -8.723  134.361 1.00 77.35  ? 311 ALA F C   1 
ATOM   16099 O O   . ALA F 1 292 ? -5.525  -8.848  135.475 1.00 76.90  ? 311 ALA F O   1 
ATOM   16100 C CB  . ALA F 1 292 ? -6.420  -10.618 132.743 1.00 75.66  ? 311 ALA F CB  1 
ATOM   16101 N N   . LYS F 1 293 ? -5.817  -7.671  133.561 1.00 74.42  ? 312 LYS F N   1 
ATOM   16102 C CA  . LYS F 1 293 ? -4.964  -6.558  133.984 1.00 74.79  ? 312 LYS F CA  1 
ATOM   16103 C C   . LYS F 1 293 ? -5.378  -6.055  135.364 1.00 76.09  ? 312 LYS F C   1 
ATOM   16104 O O   . LYS F 1 293 ? -4.555  -5.895  136.268 1.00 75.66  ? 312 LYS F O   1 
ATOM   16105 C CB  . LYS F 1 293 ? -5.019  -5.428  132.950 1.00 76.40  ? 312 LYS F CB  1 
ATOM   16106 N N   . ASP F 1 294 ? -6.659  -5.846  135.551 1.00 76.87  ? 313 ASP F N   1 
ATOM   16107 C CA  . ASP F 1 294 ? -7.176  -5.277  136.787 1.00 79.24  ? 313 ASP F CA  1 
ATOM   16108 C C   . ASP F 1 294 ? -7.277  -6.302  137.897 1.00 78.64  ? 313 ASP F C   1 
ATOM   16109 O O   . ASP F 1 294 ? -7.243  -5.918  139.066 1.00 80.02  ? 313 ASP F O   1 
ATOM   16110 C CB  . ASP F 1 294 ? -8.516  -4.601  136.431 1.00 82.46  ? 313 ASP F CB  1 
ATOM   16111 C CG  . ASP F 1 294 ? -9.322  -4.153  137.640 1.00 85.01  ? 313 ASP F CG  1 
ATOM   16112 O OD1 . ASP F 1 294 ? -8.847  -4.323  138.791 1.00 82.94  ? 313 ASP F OD1 1 
ATOM   16113 O OD2 . ASP F 1 294 ? -10.446 -3.613  137.415 1.00 89.00  ? 313 ASP F OD2 1 
ATOM   16114 N N   . SER F 1 295 ? -7.328  -7.587  137.571 1.00 78.28  ? 314 SER F N   1 
ATOM   16115 C CA  . SER F 1 295 ? -7.577  -8.631  138.549 1.00 77.99  ? 314 SER F CA  1 
ATOM   16116 C C   . SER F 1 295 ? -6.296  -9.261  139.098 1.00 75.32  ? 314 SER F C   1 
ATOM   16117 O O   . SER F 1 295 ? -6.366  -10.329 139.740 1.00 75.53  ? 314 SER F O   1 
ATOM   16118 C CB  . SER F 1 295 ? -8.466  -9.718  137.919 1.00 78.12  ? 314 SER F CB  1 
ATOM   16119 O OG  . SER F 1 295 ? -9.725  -9.208  137.493 1.00 80.59  ? 314 SER F OG  1 
ATOM   16120 N N   . LEU F 1 296 ? -5.140  -8.634  138.866 1.00 74.46  ? 315 LEU F N   1 
ATOM   16121 C CA  . LEU F 1 296 ? -3.853  -9.241  139.189 1.00 72.05  ? 315 LEU F CA  1 
ATOM   16122 C C   . LEU F 1 296 ? -3.270  -8.785  140.517 1.00 72.20  ? 315 LEU F C   1 
ATOM   16123 O O   . LEU F 1 296 ? -2.597  -9.577  141.186 1.00 70.54  ? 315 LEU F O   1 
ATOM   16124 C CB  . LEU F 1 296 ? -2.837  -8.943  138.073 1.00 70.94  ? 315 LEU F CB  1 
ATOM   16125 C CG  . LEU F 1 296 ? -1.367  -9.258  138.348 1.00 68.74  ? 315 LEU F CG  1 
ATOM   16126 C CD1 . LEU F 1 296 ? -1.057  -10.738 138.572 1.00 67.06  ? 315 LEU F CD1 1 
ATOM   16127 C CD2 . LEU F 1 296 ? -0.564  -8.725  137.170 1.00 68.56  ? 315 LEU F CD2 1 
ATOM   16128 N N   . LYS F 1 297 ? -3.521  -7.546  140.923 1.00 69.14  ? 316 LYS F N   1 
ATOM   16129 C CA  . LYS F 1 297 ? -2.839  -7.015  142.096 1.00 68.63  ? 316 LYS F CA  1 
ATOM   16130 C C   . LYS F 1 297 ? -3.106  -7.865  143.317 1.00 68.40  ? 316 LYS F C   1 
ATOM   16131 O O   . LYS F 1 297 ? -2.202  -8.106  144.118 1.00 66.86  ? 316 LYS F O   1 
ATOM   16132 C CB  . LYS F 1 297 ? -3.278  -5.576  142.373 1.00 71.56  ? 316 LYS F CB  1 
ATOM   16133 C CG  . LYS F 1 297 ? -2.677  -5.007  143.668 1.00 72.32  ? 316 LYS F CG  1 
ATOM   16134 C CD  . LYS F 1 297 ? -2.461  -3.488  143.610 1.00 75.10  ? 316 LYS F CD  1 
ATOM   16135 C CE  . LYS F 1 297 ? -3.676  -2.729  143.063 1.00 78.83  ? 316 LYS F CE  1 
ATOM   16136 N NZ  . LYS F 1 297 ? -4.964  -3.047  143.761 1.00 81.20  ? 316 LYS F NZ  1 
ATOM   16137 N N   . PHE F 1 298 ? -4.358  -8.322  143.511 1.00 71.55  ? 317 PHE F N   1 
ATOM   16138 C CA  . PHE F 1 298 ? -4.677  -9.065  144.696 1.00 71.36  ? 317 PHE F CA  1 
ATOM   16139 C C   . PHE F 1 298 ? -3.950  -10.424 144.732 1.00 68.61  ? 317 PHE F C   1 
ATOM   16140 O O   . PHE F 1 298 ? -3.111  -10.641 145.605 1.00 67.03  ? 317 PHE F O   1 
ATOM   16141 C CB  . PHE F 1 298 ? -6.180  -9.245  144.848 1.00 73.98  ? 317 PHE F CB  1 
ATOM   16142 C CG  . PHE F 1 298 ? -6.563  -9.980  146.082 1.00 73.93  ? 317 PHE F CG  1 
ATOM   16143 C CD1 . PHE F 1 298 ? -6.582  -9.339  147.316 1.00 74.00  ? 317 PHE F CD1 1 
ATOM   16144 C CD2 . PHE F 1 298 ? -6.854  -11.324 146.025 1.00 73.46  ? 317 PHE F CD2 1 
ATOM   16145 C CE1 . PHE F 1 298 ? -6.906  -10.036 148.469 1.00 73.65  ? 317 PHE F CE1 1 
ATOM   16146 C CE2 . PHE F 1 298 ? -7.190  -12.018 147.169 1.00 72.92  ? 317 PHE F CE2 1 
ATOM   16147 C CZ  . PHE F 1 298 ? -7.214  -11.378 148.395 1.00 72.82  ? 317 PHE F CZ  1 
ATOM   16148 N N   . PRO F 1 299 ? -4.239  -11.336 143.804 1.00 70.42  ? 318 PRO F N   1 
ATOM   16149 C CA  . PRO F 1 299 ? -3.522  -12.619 143.852 1.00 68.30  ? 318 PRO F CA  1 
ATOM   16150 C C   . PRO F 1 299 ? -2.016  -12.451 143.810 1.00 65.91  ? 318 PRO F C   1 
ATOM   16151 O O   . PRO F 1 299 ? -1.294  -13.245 144.433 1.00 63.89  ? 318 PRO F O   1 
ATOM   16152 C CB  . PRO F 1 299 ? -4.044  -13.356 142.612 1.00 69.34  ? 318 PRO F CB  1 
ATOM   16153 C CG  . PRO F 1 299 ? -4.489  -12.256 141.665 1.00 70.99  ? 318 PRO F CG  1 
ATOM   16154 C CD  . PRO F 1 299 ? -5.029  -11.173 142.572 1.00 72.31  ? 318 PRO F CD  1 
ATOM   16155 N N   . LEU F 1 300 ? -1.502  -11.448 143.102 1.00 65.91  ? 319 LEU F N   1 
ATOM   16156 C CA  . LEU F 1 300 ? -0.054  -11.310 143.078 1.00 64.07  ? 319 LEU F CA  1 
ATOM   16157 C C   . LEU F 1 300 ? 0.471   -10.834 144.427 1.00 63.62  ? 319 LEU F C   1 
ATOM   16158 O O   . LEU F 1 300 ? 1.486   -11.340 144.918 1.00 62.45  ? 319 LEU F O   1 
ATOM   16159 C CB  . LEU F 1 300 ? 0.376   -10.387 141.956 1.00 64.42  ? 319 LEU F CB  1 
ATOM   16160 C CG  . LEU F 1 300 ? 1.885   -10.192 141.842 1.00 62.96  ? 319 LEU F CG  1 
ATOM   16161 C CD1 . LEU F 1 300 ? 2.662   -11.460 142.059 1.00 61.12  ? 319 LEU F CD1 1 
ATOM   16162 C CD2 . LEU F 1 300 ? 2.251   -9.596  140.475 1.00 63.59  ? 319 LEU F CD2 1 
ATOM   16163 N N   . ALA F 1 301 ? -0.217  -9.892  145.068 1.00 63.89  ? 320 ALA F N   1 
ATOM   16164 C CA  . ALA F 1 301 ? 0.206   -9.501  146.409 1.00 63.97  ? 320 ALA F CA  1 
ATOM   16165 C C   . ALA F 1 301 ? 0.096   -10.679 147.366 1.00 62.88  ? 320 ALA F C   1 
ATOM   16166 O O   . ALA F 1 301 ? 1.007   -10.927 148.157 1.00 62.19  ? 320 ALA F O   1 
ATOM   16167 C CB  . ALA F 1 301 ? -0.611  -8.321  146.932 1.00 66.47  ? 320 ALA F CB  1 
ATOM   16168 N N   . CYS F 1 302 ? -1.013  -11.428 147.300 1.00 64.96  ? 321 CYS F N   1 
ATOM   16169 C CA  . CYS F 1 302 ? -1.145  -12.615 148.140 1.00 64.14  ? 321 CYS F CA  1 
ATOM   16170 C C   . CYS F 1 302 ? 0.069   -13.505 147.992 1.00 61.92  ? 321 CYS F C   1 
ATOM   16171 O O   . CYS F 1 302 ? 0.647   -13.956 148.979 1.00 61.32  ? 321 CYS F O   1 
ATOM   16172 C CB  . CYS F 1 302 ? -2.383  -13.415 147.768 1.00 65.36  ? 321 CYS F CB  1 
ATOM   16173 S SG  . CYS F 1 302 ? -3.947  -12.787 148.349 1.00 68.23  ? 321 CYS F SG  1 
ATOM   16174 N N   . PHE F 1 303 ? 0.469   -13.767 146.749 1.00 62.29  ? 322 PHE F N   1 
ATOM   16175 C CA  . PHE F 1 303 ? 1.600   -14.654 146.515 1.00 60.30  ? 322 PHE F CA  1 
ATOM   16176 C C   . PHE F 1 303 ? 2.862   -14.106 147.149 1.00 59.75  ? 322 PHE F C   1 
ATOM   16177 O O   . PHE F 1 303 ? 3.554   -14.812 147.890 1.00 58.77  ? 322 PHE F O   1 
ATOM   16178 C CB  . PHE F 1 303 ? 1.840   -14.857 145.020 1.00 59.90  ? 322 PHE F CB  1 
ATOM   16179 C CG  . PHE F 1 303 ? 3.135   -15.570 144.695 1.00 57.66  ? 322 PHE F CG  1 
ATOM   16180 C CD1 . PHE F 1 303 ? 3.237   -16.942 144.808 1.00 56.79  ? 322 PHE F CD1 1 
ATOM   16181 C CD2 . PHE F 1 303 ? 4.241   -14.864 144.264 1.00 57.52  ? 322 PHE F CD2 1 
ATOM   16182 C CE1 . PHE F 1 303 ? 4.421   -17.585 144.498 1.00 55.37  ? 322 PHE F CE1 1 
ATOM   16183 C CE2 . PHE F 1 303 ? 5.421   -15.507 143.946 1.00 55.86  ? 322 PHE F CE2 1 
ATOM   16184 C CZ  . PHE F 1 303 ? 5.511   -16.860 144.061 1.00 54.92  ? 322 PHE F CZ  1 
ATOM   16185 N N   . LEU F 1 304 ? 3.195   -12.854 146.827 1.00 57.96  ? 323 LEU F N   1 
ATOM   16186 C CA  . LEU F 1 304 ? 4.395   -12.241 147.372 1.00 57.68  ? 323 LEU F CA  1 
ATOM   16187 C C   . LEU F 1 304 ? 4.344   -12.164 148.882 1.00 58.54  ? 323 LEU F C   1 
ATOM   16188 O O   . LEU F 1 304 ? 5.390   -12.122 149.525 1.00 58.45  ? 323 LEU F O   1 
ATOM   16189 C CB  . LEU F 1 304 ? 4.582   -10.847 146.786 1.00 59.03  ? 323 LEU F CB  1 
ATOM   16190 C CG  . LEU F 1 304 ? 4.832   -10.909 145.279 1.00 58.67  ? 323 LEU F CG  1 
ATOM   16191 C CD1 . LEU F 1 304 ? 4.837   -9.541  144.637 1.00 60.23  ? 323 LEU F CD1 1 
ATOM   16192 C CD2 . LEU F 1 304 ? 6.146   -11.628 144.997 1.00 57.23  ? 323 LEU F CD2 1 
ATOM   16193 N N   . ALA F 1 305 ? 3.150   -12.158 149.461 1.00 59.30  ? 324 ALA F N   1 
ATOM   16194 C CA  . ALA F 1 305 ? 3.041   -12.128 150.911 1.00 60.26  ? 324 ALA F CA  1 
ATOM   16195 C C   . ALA F 1 305 ? 3.700   -13.357 151.529 1.00 59.02  ? 324 ALA F C   1 
ATOM   16196 O O   . ALA F 1 305 ? 4.461   -13.255 152.497 1.00 59.81  ? 324 ALA F O   1 
ATOM   16197 C CB  . ALA F 1 305 ? 1.570   -12.035 151.315 1.00 61.85  ? 324 ALA F CB  1 
ATOM   16198 N N   . GLY F 1 306 ? 3.417   -14.535 150.973 1.00 59.81  ? 325 GLY F N   1 
ATOM   16199 C CA  . GLY F 1 306 ? 3.887   -15.772 151.568 1.00 59.18  ? 325 GLY F CA  1 
ATOM   16200 C C   . GLY F 1 306 ? 5.141   -16.338 150.942 1.00 57.72  ? 325 GLY F C   1 
ATOM   16201 O O   . GLY F 1 306 ? 5.761   -17.257 151.480 1.00 57.35  ? 325 GLY F O   1 
ATOM   16202 N N   . ALA F 1 307 ? 5.549   -15.761 149.821 1.00 56.68  ? 326 ALA F N   1 
ATOM   16203 C CA  . ALA F 1 307 ? 6.521   -16.416 148.962 1.00 55.27  ? 326 ALA F CA  1 
ATOM   16204 C C   . ALA F 1 307 ? 7.865   -16.609 149.642 1.00 55.10  ? 326 ALA F C   1 
ATOM   16205 O O   . ALA F 1 307 ? 8.448   -15.660 150.173 1.00 56.33  ? 326 ALA F O   1 
ATOM   16206 C CB  . ALA F 1 307 ? 6.705   -15.609 147.679 1.00 55.24  ? 326 ALA F CB  1 
ATOM   16207 N N   . GLN F 1 308 ? 8.368   -17.838 149.569 1.00 53.65  ? 327 GLN F N   1 
ATOM   16208 C CA  . GLN F 1 308 ? 9.708   -18.214 149.985 1.00 53.24  ? 327 GLN F CA  1 
ATOM   16209 C C   . GLN F 1 308 ? 10.475  -18.745 148.784 1.00 51.62  ? 327 GLN F C   1 
ATOM   16210 O O   . GLN F 1 308 ? 9.984   -18.761 147.671 1.00 51.25  ? 327 GLN F O   1 
ATOM   16211 C CB  . GLN F 1 308 ? 9.645   -19.258 151.091 1.00 53.90  ? 327 GLN F CB  1 
ATOM   16212 C CG  . GLN F 1 308 ? 8.562   -18.990 152.124 1.00 55.77  ? 327 GLN F CG  1 
ATOM   16213 C CD  . GLN F 1 308 ? 8.930   -17.880 153.094 1.00 57.37  ? 327 GLN F CD  1 
ATOM   16214 O OE1 . GLN F 1 308 ? 10.109  -17.709 153.443 1.00 58.13  ? 327 GLN F OE1 1 
ATOM   16215 N NE2 . GLN F 1 308 ? 7.923   -17.130 153.552 1.00 58.91  ? 327 GLN F NE2 1 
ATOM   16216 N N   . GLU F 1 309 ? 11.698  -19.184 149.011 1.00 56.50  ? 328 GLU F N   1 
ATOM   16217 C CA  . GLU F 1 309 ? 12.477  -19.787 147.939 1.00 53.00  ? 328 GLU F CA  1 
ATOM   16218 C C   . GLU F 1 309 ? 11.723  -20.967 147.319 1.00 51.46  ? 328 GLU F C   1 
ATOM   16219 O O   . GLU F 1 309 ? 11.047  -21.737 148.007 1.00 52.66  ? 328 GLU F O   1 
ATOM   16220 C CB  . GLU F 1 309 ? 13.825  -20.247 148.510 1.00 50.26  ? 328 GLU F CB  1 
ATOM   16221 C CG  . GLU F 1 309 ? 15.095  -19.714 147.824 1.00 48.76  ? 328 GLU F CG  1 
ATOM   16222 C CD  . GLU F 1 309 ? 16.348  -20.573 148.129 1.00 47.67  ? 328 GLU F CD  1 
ATOM   16223 O OE1 . GLU F 1 309 ? 16.864  -21.225 147.168 1.00 46.10  ? 328 GLU F OE1 1 
ATOM   16224 O OE2 . GLU F 1 309 ? 16.794  -20.602 149.339 1.00 48.06  ? 328 GLU F OE2 1 
ATOM   16225 N N   . ASN F 1 310 ? 11.853  -21.128 146.010 1.00 50.63  ? 329 ASN F N   1 
ATOM   16226 C CA  . ASN F 1 310 ? 11.239  -22.244 145.292 1.00 49.11  ? 329 ASN F CA  1 
ATOM   16227 C C   . ASN F 1 310 ? 9.721   -22.123 145.181 1.00 52.52  ? 329 ASN F C   1 
ATOM   16228 O O   . ASN F 1 310 ? 9.034   -23.126 144.994 1.00 52.39  ? 329 ASN F O   1 
ATOM   16229 C CB  . ASN F 1 310 ? 11.548  -23.597 145.947 1.00 46.62  ? 329 ASN F CB  1 
ATOM   16230 C CG  . ASN F 1 310 ? 13.011  -23.830 146.146 1.00 43.62  ? 329 ASN F CG  1 
ATOM   16231 O OD1 . ASN F 1 310 ? 13.808  -23.706 145.200 1.00 42.67  ? 329 ASN F OD1 1 
ATOM   16232 N ND2 . ASN F 1 310 ? 13.387  -24.201 147.392 1.00 43.07  ? 329 ASN F ND2 1 
ATOM   16233 N N   . CYS F 1 311 ? 9.170   -20.928 145.333 1.00 49.94  ? 330 CYS F N   1 
ATOM   16234 C CA  . CYS F 1 311 ? 7.759   -20.683 145.079 1.00 52.00  ? 330 CYS F CA  1 
ATOM   16235 C C   . CYS F 1 311 ? 7.572   -20.033 143.716 1.00 51.94  ? 330 CYS F C   1 
ATOM   16236 O O   . CYS F 1 311 ? 8.398   -19.208 143.296 1.00 51.91  ? 330 CYS F O   1 
ATOM   16237 C CB  . CYS F 1 311 ? 7.166   -19.781 146.153 1.00 53.83  ? 330 CYS F CB  1 
ATOM   16238 S SG  . CYS F 1 311 ? 6.949   -20.577 147.708 1.00 54.47  ? 330 CYS F SG  1 
ATOM   16239 N N   . TYR F 1 312 ? 6.460   -20.389 143.051 1.00 56.99  ? 331 TYR F N   1 
ATOM   16240 C CA  . TYR F 1 312 ? 6.168   -19.936 141.701 1.00 56.75  ? 331 TYR F CA  1 
ATOM   16241 C C   . TYR F 1 312 ? 4.723   -19.510 141.555 1.00 59.18  ? 331 TYR F C   1 
ATOM   16242 O O   . TYR F 1 312 ? 3.815   -20.077 142.168 1.00 60.65  ? 331 TYR F O   1 
ATOM   16243 C CB  . TYR F 1 312 ? 6.442   -21.020 140.675 1.00 54.25  ? 331 TYR F CB  1 
ATOM   16244 C CG  . TYR F 1 312 ? 7.877   -21.345 140.621 1.00 51.38  ? 331 TYR F CG  1 
ATOM   16245 C CD1 . TYR F 1 312 ? 8.442   -22.269 141.505 1.00 49.79  ? 331 TYR F CD1 1 
ATOM   16246 C CD2 . TYR F 1 312 ? 8.704   -20.699 139.727 1.00 51.19  ? 331 TYR F CD2 1 
ATOM   16247 C CE1 . TYR F 1 312 ? 9.790   -22.558 141.464 1.00 47.41  ? 331 TYR F CE1 1 
ATOM   16248 C CE2 . TYR F 1 312 ? 10.059  -20.987 139.682 1.00 49.30  ? 331 TYR F CE2 1 
ATOM   16249 C CZ  . TYR F 1 312 ? 10.587  -21.917 140.543 1.00 47.54  ? 331 TYR F CZ  1 
ATOM   16250 O OH  . TYR F 1 312 ? 11.931  -22.170 140.484 1.00 45.96  ? 331 TYR F OH  1 
ATOM   16251 N N   . PHE F 1 313 ? 4.535   -18.513 140.694 1.00 56.29  ? 332 PHE F N   1 
ATOM   16252 C CA  . PHE F 1 313 ? 3.249   -17.910 140.376 1.00 58.48  ? 332 PHE F CA  1 
ATOM   16253 C C   . PHE F 1 313 ? 2.888   -18.236 138.930 1.00 57.92  ? 332 PHE F C   1 
ATOM   16254 O O   . PHE F 1 313 ? 3.737   -18.190 138.032 1.00 56.01  ? 332 PHE F O   1 
ATOM   16255 C CB  . PHE F 1 313 ? 3.349   -16.398 140.596 1.00 59.87  ? 332 PHE F CB  1 
ATOM   16256 C CG  . PHE F 1 313 ? 2.029   -15.646 140.648 1.00 62.01  ? 332 PHE F CG  1 
ATOM   16257 C CD1 . PHE F 1 313 ? 0.995   -16.023 141.488 1.00 63.46  ? 332 PHE F CD1 1 
ATOM   16258 C CD2 . PHE F 1 313 ? 1.866   -14.496 139.900 1.00 62.94  ? 332 PHE F CD2 1 
ATOM   16259 C CE1 . PHE F 1 313 ? -0.183  -15.263 141.539 1.00 66.00  ? 332 PHE F CE1 1 
ATOM   16260 C CE2 . PHE F 1 313 ? 0.700   -13.761 139.955 1.00 65.28  ? 332 PHE F CE2 1 
ATOM   16261 C CZ  . PHE F 1 313 ? -0.310  -14.139 140.780 1.00 66.93  ? 332 PHE F CZ  1 
ATOM   16262 N N   . ILE F 1 314 ? 1.625   -18.591 138.728 1.00 60.74  ? 333 ILE F N   1 
ATOM   16263 C CA  . ILE F 1 314 ? 0.999   -18.778 137.425 1.00 60.75  ? 333 ILE F CA  1 
ATOM   16264 C C   . ILE F 1 314 ? -0.187  -17.831 137.416 1.00 63.51  ? 333 ILE F C   1 
ATOM   16265 O O   . ILE F 1 314 ? -0.897  -17.724 138.420 1.00 65.57  ? 333 ILE F O   1 
ATOM   16266 C CB  . ILE F 1 314 ? 0.560   -20.246 137.226 1.00 60.24  ? 333 ILE F CB  1 
ATOM   16267 C CG1 . ILE F 1 314 ? 1.810   -21.136 137.321 1.00 57.43  ? 333 ILE F CG1 1 
ATOM   16268 C CG2 . ILE F 1 314 ? -0.166  -20.472 135.919 1.00 60.79  ? 333 ILE F CG2 1 
ATOM   16269 C CD1 . ILE F 1 314 ? 1.602   -22.573 136.978 1.00 56.92  ? 333 ILE F CD1 1 
ATOM   16270 N N   . TYR F 1 315 ? -0.388  -17.120 136.315 1.00 62.75  ? 334 TYR F N   1 
ATOM   16271 C CA  . TYR F 1 315 ? -1.509  -16.201 136.226 1.00 65.35  ? 334 TYR F CA  1 
ATOM   16272 C C   . TYR F 1 315 ? -2.100  -16.294 134.836 1.00 65.44  ? 334 TYR F C   1 
ATOM   16273 O O   . TYR F 1 315 ? -1.425  -15.982 133.849 1.00 65.26  ? 334 TYR F O   1 
ATOM   16274 C CB  . TYR F 1 315 ? -1.078  -14.770 136.524 1.00 65.99  ? 334 TYR F CB  1 
ATOM   16275 C CG  . TYR F 1 315 ? -2.224  -13.799 136.637 1.00 68.58  ? 334 TYR F CG  1 
ATOM   16276 C CD1 . TYR F 1 315 ? -2.994  -13.739 137.796 1.00 70.46  ? 334 TYR F CD1 1 
ATOM   16277 C CD2 . TYR F 1 315 ? -2.533  -12.934 135.589 1.00 69.32  ? 334 TYR F CD2 1 
ATOM   16278 C CE1 . TYR F 1 315 ? -4.038  -12.840 137.906 1.00 72.88  ? 334 TYR F CE1 1 
ATOM   16279 C CE2 . TYR F 1 315 ? -3.566  -12.035 135.689 1.00 71.73  ? 334 TYR F CE2 1 
ATOM   16280 C CZ  . TYR F 1 315 ? -4.312  -11.996 136.851 1.00 73.49  ? 334 TYR F CZ  1 
ATOM   16281 O OH  . TYR F 1 315 ? -5.350  -11.113 136.952 1.00 76.17  ? 334 TYR F OH  1 
ATOM   16282 N N   . ASN F 1 316 ? -3.351  -16.719 134.769 1.00 68.22  ? 335 ASN F N   1 
ATOM   16283 C CA  . ASN F 1 316 ? -4.127  -16.831 133.532 1.00 69.43  ? 335 ASN F CA  1 
ATOM   16284 C C   . ASN F 1 316 ? -5.553  -17.164 133.961 1.00 71.69  ? 335 ASN F C   1 
ATOM   16285 O O   . ASN F 1 316 ? -5.893  -17.051 135.146 1.00 72.72  ? 335 ASN F O   1 
ATOM   16286 C CB  . ASN F 1 316 ? -3.518  -17.860 132.586 1.00 69.43  ? 335 ASN F CB  1 
ATOM   16287 C CG  . ASN F 1 316 ? -3.293  -19.187 133.253 1.00 68.12  ? 335 ASN F CG  1 
ATOM   16288 O OD1 . ASN F 1 316 ? -4.211  -19.771 133.822 1.00 69.02  ? 335 ASN F OD1 1 
ATOM   16289 N ND2 . ASN F 1 316 ? -2.064  -19.667 133.204 1.00 66.21  ? 335 ASN F ND2 1 
ATOM   16290 N N   . TRP F 1 317 ? -6.403  -17.547 133.006 1.00 73.52  ? 336 TRP F N   1 
ATOM   16291 C CA  . TRP F 1 317 ? -7.781  -17.904 133.324 1.00 76.38  ? 336 TRP F CA  1 
ATOM   16292 C C   . TRP F 1 317 ? -8.124  -19.316 132.856 1.00 77.76  ? 336 TRP F C   1 
ATOM   16293 O O   . TRP F 1 317 ? -9.301  -19.645 132.683 1.00 80.29  ? 336 TRP F O   1 
ATOM   16294 C CB  . TRP F 1 317 ? -8.767  -16.879 132.746 1.00 79.30  ? 336 TRP F CB  1 
ATOM   16295 C CG  . TRP F 1 317 ? -8.728  -16.609 131.237 1.00 80.70  ? 336 TRP F CG  1 
ATOM   16296 C CD1 . TRP F 1 317 ? -9.384  -17.305 130.258 1.00 83.22  ? 336 TRP F CD1 1 
ATOM   16297 C CD2 . TRP F 1 317 ? -8.051  -15.521 130.561 1.00 80.14  ? 336 TRP F CD2 1 
ATOM   16298 N NE1 . TRP F 1 317 ? -9.140  -16.736 129.024 1.00 84.25  ? 336 TRP F NE1 1 
ATOM   16299 C CE2 . TRP F 1 317 ? -8.332  -15.642 129.181 1.00 82.39  ? 336 TRP F CE2 1 
ATOM   16300 C CE3 . TRP F 1 317 ? -7.234  -14.469 130.987 1.00 78.11  ? 336 TRP F CE3 1 
ATOM   16301 C CZ2 . TRP F 1 317 ? -7.808  -14.761 128.229 1.00 82.63  ? 336 TRP F CZ2 1 
ATOM   16302 C CZ3 . TRP F 1 317 ? -6.724  -13.588 130.034 1.00 78.34  ? 336 TRP F CZ3 1 
ATOM   16303 C CH2 . TRP F 1 317 ? -7.007  -13.746 128.677 1.00 80.56  ? 336 TRP F CH2 1 
ATOM   16304 N N   . GLY F 1 318 ? -7.123  -20.172 132.689 1.00 76.33  ? 337 GLY F N   1 
ATOM   16305 C CA  . GLY F 1 318 ? -7.381  -21.518 132.227 1.00 77.27  ? 337 GLY F CA  1 
ATOM   16306 C C   . GLY F 1 318 ? -6.102  -22.184 131.770 1.00 75.55  ? 337 GLY F C   1 
ATOM   16307 O O   . GLY F 1 318 ? -5.002  -21.644 131.935 1.00 73.24  ? 337 GLY F O   1 
ATOM   16308 N N   . TYR F 1 319 ? -6.270  -23.375 131.186 1.00 76.91  ? 338 TYR F N   1 
ATOM   16309 C CA  . TYR F 1 319 ? -5.131  -24.253 130.958 1.00 75.53  ? 338 TYR F CA  1 
ATOM   16310 C C   . TYR F 1 319 ? -4.797  -24.457 129.490 1.00 77.05  ? 338 TYR F C   1 
ATOM   16311 O O   . TYR F 1 319 ? -3.758  -25.062 129.196 1.00 75.95  ? 338 TYR F O   1 
ATOM   16312 C CB  . TYR F 1 319 ? -5.363  -25.623 131.625 1.00 75.67  ? 338 TYR F CB  1 
ATOM   16313 C CG  . TYR F 1 319 ? -5.438  -25.560 133.134 1.00 74.09  ? 338 TYR F CG  1 
ATOM   16314 C CD1 . TYR F 1 319 ? -4.341  -25.161 133.891 1.00 71.17  ? 338 TYR F CD1 1 
ATOM   16315 C CD2 . TYR F 1 319 ? -6.608  -25.904 133.805 1.00 75.72  ? 338 TYR F CD2 1 
ATOM   16316 C CE1 . TYR F 1 319 ? -4.405  -25.101 135.269 1.00 69.24  ? 338 TYR F CE1 1 
ATOM   16317 C CE2 . TYR F 1 319 ? -6.683  -25.844 135.190 1.00 74.72  ? 338 TYR F CE2 1 
ATOM   16318 C CZ  . TYR F 1 319 ? -5.572  -25.443 135.914 1.00 71.29  ? 338 TYR F CZ  1 
ATOM   16319 O OH  . TYR F 1 319 ? -5.615  -25.386 137.289 1.00 72.15  ? 338 TYR F OH  1 
ATOM   16320 N N   . ARG F 1 320 ? -5.661  -24.016 128.572 1.00 79.85  ? 339 ARG F N   1 
ATOM   16321 C CA  . ARG F 1 320 ? -5.301  -23.973 127.159 1.00 81.22  ? 339 ARG F CA  1 
ATOM   16322 C C   . ARG F 1 320 ? -4.469  -22.718 126.963 1.00 79.58  ? 339 ARG F C   1 
ATOM   16323 O O   . ARG F 1 320 ? -4.704  -21.693 127.618 1.00 78.63  ? 339 ARG F O   1 
ATOM   16324 C CB  . ARG F 1 320 ? -6.542  -23.967 126.262 1.00 85.15  ? 339 ARG F CB  1 
ATOM   16325 N N   . MET F 1 321 ? -3.457  -22.799 126.106 1.00 83.81  ? 340 MET F N   1 
ATOM   16326 C CA  . MET F 1 321 ? -2.570  -21.653 125.957 1.00 82.61  ? 340 MET F CA  1 
ATOM   16327 C C   . MET F 1 321 ? -3.345  -20.367 125.676 1.00 83.81  ? 340 MET F C   1 
ATOM   16328 O O   . MET F 1 321 ? -2.953  -19.292 126.146 1.00 82.13  ? 340 MET F O   1 
ATOM   16329 C CB  . MET F 1 321 ? -1.572  -21.953 124.854 1.00 83.12  ? 340 MET F CB  1 
ATOM   16330 C CG  . MET F 1 321 ? -1.283  -20.789 123.979 1.00 84.01  ? 340 MET F CG  1 
ATOM   16331 S SD  . MET F 1 321 ? 0.087   -21.264 122.921 1.00 84.72  ? 340 MET F SD  1 
ATOM   16332 C CE  . MET F 1 321 ? 0.135   -19.820 121.843 1.00 86.59  ? 340 MET F CE  1 
ATOM   16333 N N   . GLU F 1 322 ? -4.468  -20.461 124.956 1.00 82.10  ? 341 GLU F N   1 
ATOM   16334 C CA  . GLU F 1 322 ? -5.267  -19.290 124.600 1.00 83.70  ? 341 GLU F CA  1 
ATOM   16335 C C   . GLU F 1 322 ? -6.024  -18.690 125.783 1.00 82.87  ? 341 GLU F C   1 
ATOM   16336 O O   . GLU F 1 322 ? -6.653  -17.644 125.610 1.00 83.86  ? 341 GLU F O   1 
ATOM   16337 C CB  . GLU F 1 322 ? -6.235  -19.675 123.474 1.00 87.63  ? 341 GLU F CB  1 
ATOM   16338 C CG  . GLU F 1 322 ? -5.575  -20.501 122.340 1.00 89.91  ? 341 GLU F CG  1 
ATOM   16339 C CD  . GLU F 1 322 ? -5.644  -22.031 122.547 1.00 91.11  ? 341 GLU F CD  1 
ATOM   16340 O OE1 . GLU F 1 322 ? -6.459  -22.514 123.361 1.00 90.94  ? 341 GLU F OE1 1 
ATOM   16341 O OE2 . GLU F 1 322 ? -4.859  -22.766 121.907 1.00 92.16  ? 341 GLU F OE2 1 
ATOM   16342 N N   . ASN F 1 323 ? -5.966  -19.283 126.970 1.00 81.51  ? 342 ASN F N   1 
ATOM   16343 C CA  . ASN F 1 323 ? -6.600  -18.676 128.139 1.00 80.97  ? 342 ASN F CA  1 
ATOM   16344 C C   . ASN F 1 323 ? -5.684  -17.690 128.858 1.00 78.16  ? 342 ASN F C   1 
ATOM   16345 O O   . ASN F 1 323 ? -5.595  -17.751 130.073 1.00 76.41  ? 342 ASN F O   1 
ATOM   16346 C CB  . ASN F 1 323 ? -7.024  -19.740 129.139 1.00 80.62  ? 342 ASN F CB  1 
ATOM   16347 C CG  . ASN F 1 323 ? -8.038  -20.676 128.589 1.00 83.27  ? 342 ASN F CG  1 
ATOM   16348 O OD1 . ASN F 1 323 ? -7.714  -21.792 128.136 1.00 83.84  ? 342 ASN F OD1 1 
ATOM   16349 N ND2 . ASN F 1 323 ? -9.294  -20.260 128.651 1.00 85.67  ? 342 ASN F ND2 1 
ATOM   16350 N N   . GLY F 1 324 ? -5.007  -16.801 128.136 1.00 78.98  ? 343 GLY F N   1 
ATOM   16351 C CA  . GLY F 1 324 ? -4.219  -15.766 128.794 1.00 76.85  ? 343 GLY F CA  1 
ATOM   16352 C C   . GLY F 1 324 ? -2.878  -16.218 129.330 1.00 74.00  ? 343 GLY F C   1 
ATOM   16353 O O   . GLY F 1 324 ? -2.170  -15.432 129.987 1.00 72.04  ? 343 GLY F O   1 
ATOM   16354 N N   . CYS F 1 325 ? -2.503  -17.463 129.055 1.00 75.98  ? 344 CYS F N   1 
ATOM   16355 C CA  . CYS F 1 325 ? -1.258  -18.008 129.577 1.00 73.13  ? 344 CYS F CA  1 
ATOM   16356 C C   . CYS F 1 325 ? -0.049  -17.211 129.100 1.00 71.81  ? 344 CYS F C   1 
ATOM   16357 O O   . CYS F 1 325 ? 0.922   -17.031 129.847 1.00 69.73  ? 344 CYS F O   1 
ATOM   16358 C CB  . CYS F 1 325 ? -1.146  -19.468 129.165 1.00 74.05  ? 344 CYS F CB  1 
ATOM   16359 S SG  . CYS F 1 325 ? -2.476  -20.509 129.799 1.00 75.92  ? 344 CYS F SG  1 
ATOM   16360 N N   . LEU F 1 326 ? -0.084  -16.726 127.861 1.00 73.51  ? 345 LEU F N   1 
ATOM   16361 C CA  . LEU F 1 326 ? 1.017   -15.959 127.299 1.00 72.71  ? 345 LEU F CA  1 
ATOM   16362 C C   . LEU F 1 326 ? 0.761   -14.459 127.323 1.00 73.37  ? 345 LEU F C   1 
ATOM   16363 O O   . LEU F 1 326 ? 1.458   -13.714 126.637 1.00 73.78  ? 345 LEU F O   1 
ATOM   16364 C CB  . LEU F 1 326 ? 1.315   -16.403 125.864 1.00 74.92  ? 345 LEU F CB  1 
ATOM   16365 C CG  . LEU F 1 326 ? 1.551   -17.904 125.691 1.00 75.45  ? 345 LEU F CG  1 
ATOM   16366 C CD1 . LEU F 1 326 ? 2.085   -18.245 124.313 1.00 77.79  ? 345 LEU F CD1 1 
ATOM   16367 C CD2 . LEU F 1 326 ? 2.496   -18.436 126.778 1.00 72.41  ? 345 LEU F CD2 1 
ATOM   16368 N N   . GLU F 1 327 ? -0.213  -13.992 128.094 1.00 70.43  ? 346 GLU F N   1 
ATOM   16369 C CA  . GLU F 1 327 ? -0.228  -12.577 128.447 1.00 70.34  ? 346 GLU F CA  1 
ATOM   16370 C C   . GLU F 1 327 ? 0.933   -12.256 129.387 1.00 67.72  ? 346 GLU F C   1 
ATOM   16371 O O   . GLU F 1 327 ? 1.332   -13.063 130.221 1.00 66.91  ? 346 GLU F O   1 
ATOM   16372 C CB  . GLU F 1 327 ? -1.546  -12.211 129.110 1.00 71.58  ? 346 GLU F CB  1 
ATOM   16373 C CG  . GLU F 1 327 ? -2.753  -12.459 128.225 1.00 74.95  ? 346 GLU F CG  1 
ATOM   16374 C CD  . GLU F 1 327 ? -2.821  -11.523 127.035 1.00 77.86  ? 346 GLU F CD  1 
ATOM   16375 O OE1 . GLU F 1 327 ? -1.796  -11.243 126.382 1.00 77.91  ? 346 GLU F OE1 1 
ATOM   16376 O OE2 . GLU F 1 327 ? -3.928  -11.067 126.734 1.00 80.66  ? 346 GLU F OE2 1 
ATOM   16377 N N   . TRP F 1 328 ? 1.504   -11.077 129.234 1.00 70.68  ? 347 TRP F N   1 
ATOM   16378 C CA  . TRP F 1 328 ? 2.542   -10.643 130.156 1.00 68.15  ? 347 TRP F CA  1 
ATOM   16379 C C   . TRP F 1 328 ? 2.069   -9.383  130.858 1.00 69.26  ? 347 TRP F C   1 
ATOM   16380 O O   . TRP F 1 328 ? 1.111   -8.747  130.439 1.00 71.33  ? 347 TRP F O   1 
ATOM   16381 C CB  . TRP F 1 328 ? 3.891   -10.404 129.474 1.00 67.50  ? 347 TRP F CB  1 
ATOM   16382 C CG  . TRP F 1 328 ? 5.050   -10.614 130.459 1.00 64.80  ? 347 TRP F CG  1 
ATOM   16383 C CD1 . TRP F 1 328 ? 5.864   -9.649  130.979 1.00 63.82  ? 347 TRP F CD1 1 
ATOM   16384 C CD2 . TRP F 1 328 ? 5.477   -11.851 131.063 1.00 63.03  ? 347 TRP F CD2 1 
ATOM   16385 N NE1 . TRP F 1 328 ? 6.781   -10.206 131.848 1.00 62.46  ? 347 TRP F NE1 1 
ATOM   16386 C CE2 . TRP F 1 328 ? 6.559   -11.553 131.922 1.00 61.67  ? 347 TRP F CE2 1 
ATOM   16387 C CE3 . TRP F 1 328 ? 5.066   -13.172 130.951 1.00 63.23  ? 347 TRP F CE3 1 
ATOM   16388 C CZ2 . TRP F 1 328 ? 7.229   -12.540 132.658 1.00 60.23  ? 347 TRP F CZ2 1 
ATOM   16389 C CZ3 . TRP F 1 328 ? 5.750   -14.150 131.689 1.00 61.54  ? 347 TRP F CZ3 1 
ATOM   16390 C CH2 . TRP F 1 328 ? 6.801   -13.826 132.526 1.00 60.25  ? 347 TRP F CH2 1 
ATOM   16391 N N   . TYR F 1 329 ? 2.675   -9.081  131.990 1.00 64.97  ? 348 TYR F N   1 
ATOM   16392 C CA  . TYR F 1 329 ? 2.218   -7.986  132.805 1.00 66.39  ? 348 TYR F CA  1 
ATOM   16393 C C   . TYR F 1 329 ? 3.428   -7.195  133.291 1.00 65.24  ? 348 TYR F C   1 
ATOM   16394 O O   . TYR F 1 329 ? 4.459   -7.804  133.632 1.00 63.60  ? 348 TYR F O   1 
ATOM   16395 C CB  . TYR F 1 329 ? 1.394   -8.498  133.981 1.00 67.75  ? 348 TYR F CB  1 
ATOM   16396 C CG  . TYR F 1 329 ? 0.084   -9.160  133.576 1.00 69.14  ? 348 TYR F CG  1 
ATOM   16397 C CD1 . TYR F 1 329 ? 0.051   -10.341 132.822 1.00 68.26  ? 348 TYR F CD1 1 
ATOM   16398 C CD2 . TYR F 1 329 ? -1.130  -8.605  133.962 1.00 71.54  ? 348 TYR F CD2 1 
ATOM   16399 C CE1 . TYR F 1 329 ? -1.162  -10.941 132.451 1.00 69.85  ? 348 TYR F CE1 1 
ATOM   16400 C CE2 . TYR F 1 329 ? -2.339  -9.194  133.622 1.00 72.82  ? 348 TYR F CE2 1 
ATOM   16401 C CZ  . TYR F 1 329 ? -2.344  -10.366 132.870 1.00 72.01  ? 348 TYR F CZ  1 
ATOM   16402 O OH  . TYR F 1 329 ? -3.533  -10.950 132.541 1.00 73.90  ? 348 TYR F OH  1 
ATOM   16403 N N   . PRO F 1 330 ? 3.353   -5.854  133.316 1.00 61.47  ? 349 PRO F N   1 
ATOM   16404 C CA  . PRO F 1 330 ? 4.557   -5.081  133.700 1.00 60.40  ? 349 PRO F CA  1 
ATOM   16405 C C   . PRO F 1 330 ? 5.070   -5.433  135.096 1.00 59.63  ? 349 PRO F C   1 
ATOM   16406 O O   . PRO F 1 330 ? 6.275   -5.316  135.360 1.00 58.29  ? 349 PRO F O   1 
ATOM   16407 C CB  . PRO F 1 330 ? 4.092   -3.613  133.586 1.00 62.40  ? 349 PRO F CB  1 
ATOM   16408 C CG  . PRO F 1 330 ? 2.607   -3.680  133.804 1.00 64.59  ? 349 PRO F CG  1 
ATOM   16409 C CD  . PRO F 1 330 ? 2.172   -4.983  133.140 1.00 63.78  ? 349 PRO F CD  1 
ATOM   16410 N N   . GLU F 1 331 ? 4.185   -5.905  135.976 1.00 60.19  ? 350 GLU F N   1 
ATOM   16411 C CA  . GLU F 1 331 ? 4.585   -6.336  137.310 1.00 60.13  ? 350 GLU F CA  1 
ATOM   16412 C C   . GLU F 1 331 ? 5.604   -7.470  137.281 1.00 58.01  ? 350 GLU F C   1 
ATOM   16413 O O   . GLU F 1 331 ? 6.429   -7.567  138.199 1.00 58.10  ? 350 GLU F O   1 
ATOM   16414 C CB  . GLU F 1 331 ? 3.358   -6.796  138.108 1.00 62.91  ? 350 GLU F CB  1 
ATOM   16415 C CG  . GLU F 1 331 ? 2.426   -5.684  138.582 1.00 65.38  ? 350 GLU F CG  1 
ATOM   16416 C CD  . GLU F 1 331 ? 1.473   -5.199  137.510 1.00 67.15  ? 350 GLU F CD  1 
ATOM   16417 O OE1 . GLU F 1 331 ? 1.490   -5.743  136.382 1.00 65.81  ? 350 GLU F OE1 1 
ATOM   16418 O OE2 . GLU F 1 331 ? 0.710   -4.246  137.784 1.00 69.74  ? 350 GLU F OE2 1 
ATOM   16419 N N   . PHE F 1 332 ? 5.540   -8.362  136.277 1.00 59.37  ? 351 PHE F N   1 
ATOM   16420 C CA  . PHE F 1 332 ? 6.509   -9.450  136.173 1.00 56.99  ? 351 PHE F CA  1 
ATOM   16421 C C   . PHE F 1 332 ? 7.872   -8.995  135.645 1.00 55.17  ? 351 PHE F C   1 
ATOM   16422 O O   . PHE F 1 332 ? 8.772   -9.814  135.509 1.00 53.64  ? 351 PHE F O   1 
ATOM   16423 C CB  . PHE F 1 332 ? 5.995   -10.587 135.260 1.00 56.83  ? 351 PHE F CB  1 
ATOM   16424 C CG  . PHE F 1 332 ? 4.668   -11.209 135.689 1.00 58.61  ? 351 PHE F CG  1 
ATOM   16425 C CD1 . PHE F 1 332 ? 4.097   -10.919 136.917 1.00 60.98  ? 351 PHE F CD1 1 
ATOM   16426 C CD2 . PHE F 1 332 ? 3.979   -12.062 134.832 1.00 58.97  ? 351 PHE F CD2 1 
ATOM   16427 C CE1 . PHE F 1 332 ? 2.878   -11.470 137.280 1.00 63.63  ? 351 PHE F CE1 1 
ATOM   16428 C CE2 . PHE F 1 332 ? 2.772   -12.610 135.205 1.00 61.04  ? 351 PHE F CE2 1 
ATOM   16429 C CZ  . PHE F 1 332 ? 2.222   -12.308 136.427 1.00 63.56  ? 351 PHE F CZ  1 
ATOM   16430 N N   . ASP F 1 333 ? 8.051   -7.722  135.310 1.00 57.11  ? 352 ASP F N   1 
ATOM   16431 C CA  . ASP F 1 333 ? 9.338   -7.220  134.840 1.00 56.02  ? 352 ASP F CA  1 
ATOM   16432 C C   . ASP F 1 333 ? 10.011  -6.306  135.844 1.00 56.16  ? 352 ASP F C   1 
ATOM   16433 O O   . ASP F 1 333 ? 11.215  -6.057  135.720 1.00 55.75  ? 352 ASP F O   1 
ATOM   16434 C CB  . ASP F 1 333 ? 9.160   -6.501  133.495 1.00 57.04  ? 352 ASP F CB  1 
ATOM   16435 C CG  . ASP F 1 333 ? 8.710   -7.469  132.403 1.00 57.35  ? 352 ASP F CG  1 
ATOM   16436 O OD1 . ASP F 1 333 ? 9.006   -8.689  132.582 1.00 55.94  ? 352 ASP F OD1 1 
ATOM   16437 O OD2 . ASP F 1 333 ? 8.050   -7.052  131.415 1.00 59.01  ? 352 ASP F OD2 1 
ATOM   16438 N N   . LYS F 1 334 ? 9.295   -5.874  136.868 1.00 53.69  ? 353 LYS F N   1 
ATOM   16439 C CA  . LYS F 1 334 ? 9.821   -4.954  137.852 1.00 54.35  ? 353 LYS F CA  1 
ATOM   16440 C C   . LYS F 1 334 ? 10.772  -5.645  138.813 1.00 52.88  ? 353 LYS F C   1 
ATOM   16441 O O   . LYS F 1 334 ? 10.620  -6.823  139.121 1.00 52.68  ? 353 LYS F O   1 
ATOM   16442 C CB  . LYS F 1 334 ? 8.681   -4.316  138.625 1.00 57.44  ? 353 LYS F CB  1 
ATOM   16443 C CG  . LYS F 1 334 ? 7.865   -3.488  137.712 1.00 59.15  ? 353 LYS F CG  1 
ATOM   16444 C CD  . LYS F 1 334 ? 7.153   -2.370  138.405 1.00 62.15  ? 353 LYS F CD  1 
ATOM   16445 C CE  . LYS F 1 334 ? 7.636   -1.024  137.850 1.00 63.08  ? 353 LYS F CE  1 
ATOM   16446 N NZ  . LYS F 1 334 ? 9.002   -0.681  138.432 1.00 62.09  ? 353 LYS F NZ  1 
ATOM   16447 N N   . PRO F 1 335 ? 11.778  -4.917  139.274 1.00 51.78  ? 354 PRO F N   1 
ATOM   16448 C CA  . PRO F 1 335 ? 12.719  -5.504  140.237 1.00 50.74  ? 354 PRO F CA  1 
ATOM   16449 C C   . PRO F 1 335 ? 12.023  -5.931  141.516 1.00 52.16  ? 354 PRO F C   1 
ATOM   16450 O O   . PRO F 1 335 ? 11.269  -5.171  142.123 1.00 54.06  ? 354 PRO F O   1 
ATOM   16451 C CB  . PRO F 1 335 ? 13.718  -4.368  140.482 1.00 51.28  ? 354 PRO F CB  1 
ATOM   16452 C CG  . PRO F 1 335 ? 13.691  -3.602  139.175 1.00 51.69  ? 354 PRO F CG  1 
ATOM   16453 C CD  . PRO F 1 335 ? 12.244  -3.616  138.759 1.00 52.28  ? 354 PRO F CD  1 
ATOM   16454 N N   . LEU F 1 336 ? 12.317  -7.151  141.946 1.00 50.72  ? 355 LEU F N   1 
ATOM   16455 C CA  . LEU F 1 336 ? 11.830  -7.661  143.222 1.00 51.80  ? 355 LEU F CA  1 
ATOM   16456 C C   . LEU F 1 336 ? 12.950  -7.808  144.243 1.00 50.95  ? 355 LEU F C   1 
ATOM   16457 O O   . LEU F 1 336 ? 12.940  -7.120  145.272 1.00 51.90  ? 355 LEU F O   1 
ATOM   16458 C CB  . LEU F 1 336 ? 11.113  -8.993  142.968 1.00 52.15  ? 355 LEU F CB  1 
ATOM   16459 C CG  . LEU F 1 336 ? 10.500  -9.731  144.161 1.00 52.98  ? 355 LEU F CG  1 
ATOM   16460 C CD1 . LEU F 1 336 ? 9.406   -8.877  144.773 1.00 54.55  ? 355 LEU F CD1 1 
ATOM   16461 C CD2 . LEU F 1 336 ? 9.972   -11.099 143.780 1.00 53.17  ? 355 LEU F CD2 1 
ATOM   16462 N N   . GLY F 1 337 ? 13.911  -8.700  143.988 1.00 51.52  ? 356 GLY F N   1 
ATOM   16463 C CA  . GLY F 1 337 ? 14.998  -8.951  144.912 1.00 50.71  ? 356 GLY F CA  1 
ATOM   16464 C C   . GLY F 1 337 ? 14.575  -9.792  146.094 1.00 50.98  ? 356 GLY F C   1 
ATOM   16465 O O   . GLY F 1 337 ? 13.390  -10.047 146.323 1.00 52.35  ? 356 GLY F O   1 
ATOM   16466 N N   . LYS F 1 338 ? 15.578  -10.228 146.874 1.00 51.14  ? 357 LYS F N   1 
ATOM   16467 C CA  . LYS F 1 338 ? 15.319  -11.184 147.949 1.00 51.78  ? 357 LYS F CA  1 
ATOM   16468 C C   . LYS F 1 338 ? 14.348  -10.569 148.955 1.00 53.43  ? 357 LYS F C   1 
ATOM   16469 O O   . LYS F 1 338 ? 14.253  -9.352  149.078 1.00 54.25  ? 357 LYS F O   1 
ATOM   16470 C CB  . LYS F 1 338 ? 16.610  -11.609 148.666 1.00 50.25  ? 357 LYS F CB  1 
ATOM   16471 C CG  . LYS F 1 338 ? 17.640  -10.502 148.871 1.00 50.86  ? 357 LYS F CG  1 
ATOM   16472 C CD  . LYS F 1 338 ? 18.955  -10.922 149.596 1.00 48.96  ? 357 LYS F CD  1 
ATOM   16473 C CE  . LYS F 1 338 ? 19.809  -9.641  149.980 1.00 50.05  ? 357 LYS F CE  1 
ATOM   16474 N NZ  . LYS F 1 338 ? 20.684  -9.743  151.243 1.00 49.58  ? 357 LYS F NZ  1 
ATOM   16475 N N   . PRO F 1 339 ? 13.581  -11.388 149.653 1.00 51.61  ? 358 PRO F N   1 
ATOM   16476 C CA  . PRO F 1 339 ? 12.837  -10.876 150.806 1.00 53.03  ? 358 PRO F CA  1 
ATOM   16477 C C   . PRO F 1 339 ? 13.807  -10.415 151.880 1.00 52.52  ? 358 PRO F C   1 
ATOM   16478 O O   . PRO F 1 339 ? 14.815  -11.074 152.159 1.00 51.07  ? 358 PRO F O   1 
ATOM   16479 C CB  . PRO F 1 339 ? 12.017  -12.083 151.274 1.00 53.64  ? 358 PRO F CB  1 
ATOM   16480 C CG  . PRO F 1 339 ? 12.007  -13.014 150.160 1.00 53.45  ? 358 PRO F CG  1 
ATOM   16481 C CD  . PRO F 1 339 ? 13.224  -12.776 149.324 1.00 51.65  ? 358 PRO F CD  1 
ATOM   16482 N N   . VAL F 1 340 ? 13.499  -9.267  152.485 1.00 53.55  ? 359 VAL F N   1 
ATOM   16483 C CA  . VAL F 1 340 ? 14.285  -8.731  153.592 1.00 53.36  ? 359 VAL F CA  1 
ATOM   16484 C C   . VAL F 1 340 ? 13.584  -8.899  154.927 1.00 54.85  ? 359 VAL F C   1 
ATOM   16485 O O   . VAL F 1 340 ? 14.114  -8.453  155.961 1.00 55.47  ? 359 VAL F O   1 
ATOM   16486 C CB  . VAL F 1 340 ? 14.655  -7.255  153.358 1.00 54.74  ? 359 VAL F CB  1 
ATOM   16487 C CG1 . VAL F 1 340 ? 15.387  -7.106  152.033 1.00 54.32  ? 359 VAL F CG1 1 
ATOM   16488 C CG2 . VAL F 1 340 ? 13.420  -6.395  153.400 1.00 56.89  ? 359 VAL F CG2 1 
ATOM   16489 N N   . GLY F 1 341 ? 12.426  -9.554  154.951 1.00 56.95  ? 360 GLY F N   1 
ATOM   16490 C CA  . GLY F 1 341 ? 11.765  -9.845  156.209 1.00 57.90  ? 360 GLY F CA  1 
ATOM   16491 C C   . GLY F 1 341 ? 10.796  -10.982 156.016 1.00 58.53  ? 360 GLY F C   1 
ATOM   16492 O O   . GLY F 1 341 ? 10.471  -11.363 154.893 1.00 58.52  ? 360 GLY F O   1 
ATOM   16493 N N   . GLU F 1 342 ? 10.330  -11.514 157.133 1.00 59.25  ? 361 GLU F N   1 
ATOM   16494 C CA  . GLU F 1 342 ? 9.332   -12.555 157.068 1.00 60.59  ? 361 GLU F CA  1 
ATOM   16495 C C   . GLU F 1 342 ? 7.949   -11.951 156.943 1.00 62.89  ? 361 GLU F C   1 
ATOM   16496 O O   . GLU F 1 342 ? 7.698   -10.822 157.331 1.00 64.28  ? 361 GLU F O   1 
ATOM   16497 C CB  . GLU F 1 342 ? 9.386   -13.443 158.305 1.00 61.45  ? 361 GLU F CB  1 
ATOM   16498 C CG  . GLU F 1 342 ? 10.777  -13.924 158.644 1.00 59.56  ? 361 GLU F CG  1 
ATOM   16499 C CD  . GLU F 1 342 ? 11.267  -15.070 157.742 1.00 58.73  ? 361 GLU F CD  1 
ATOM   16500 O OE1 . GLU F 1 342 ? 10.443  -15.717 157.039 1.00 59.43  ? 361 GLU F OE1 1 
ATOM   16501 O OE2 . GLU F 1 342 ? 12.503  -15.324 157.751 1.00 57.45  ? 361 GLU F OE2 1 
ATOM   16502 N N   . MET F 1 343 ? 7.028   -12.745 156.439 1.00 62.33  ? 362 MET F N   1 
ATOM   16503 C CA  . MET F 1 343 ? 5.657   -12.277 156.346 1.00 65.20  ? 362 MET F CA  1 
ATOM   16504 C C   . MET F 1 343 ? 5.153   -11.867 157.726 1.00 67.47  ? 362 MET F C   1 
ATOM   16505 O O   . MET F 1 343 ? 5.378   -12.569 158.718 1.00 67.70  ? 362 MET F O   1 
ATOM   16506 C CB  . MET F 1 343 ? 4.766   -13.368 155.752 1.00 66.01  ? 362 MET F CB  1 
ATOM   16507 C CG  . MET F 1 343 ? 3.367   -12.849 155.427 1.00 68.76  ? 362 MET F CG  1 
ATOM   16508 S SD  . MET F 1 343 ? 2.258   -14.063 154.697 1.00 70.02  ? 362 MET F SD  1 
ATOM   16509 C CE  . MET F 1 343 ? 2.146   -15.197 156.098 1.00 71.91  ? 362 MET F CE  1 
ATOM   16510 N N   . VAL F 1 344 ? 4.470   -10.722 157.782 1.00 65.99  ? 363 VAL F N   1 
ATOM   16511 C CA  . VAL F 1 344 ? 3.779   -10.253 158.978 1.00 68.58  ? 363 VAL F CA  1 
ATOM   16512 C C   . VAL F 1 344 ? 2.268   -10.390 158.796 1.00 71.35  ? 363 VAL F C   1 
ATOM   16513 O O   . VAL F 1 344 ? 1.742   -10.180 157.696 1.00 71.36  ? 363 VAL F O   1 
ATOM   16514 C CB  . VAL F 1 344 ? 4.164   -8.790  159.288 1.00 69.31  ? 363 VAL F CB  1 
ATOM   16515 C CG1 . VAL F 1 344 ? 3.116   -8.121  160.170 1.00 73.00  ? 363 VAL F CG1 1 
ATOM   16516 C CG2 . VAL F 1 344 ? 5.549   -8.719  159.925 1.00 67.74  ? 363 VAL F CG2 1 
ATOM   16517 N N   . ARG F 1 345 ? 1.574   -10.713 159.899 1.00 72.21  ? 364 ARG F N   1 
ATOM   16518 C CA  . ARG F 1 345 ? 0.124   -10.866 159.909 1.00 75.18  ? 364 ARG F CA  1 
ATOM   16519 C C   . ARG F 1 345 ? -0.481  -10.125 161.093 1.00 77.98  ? 364 ARG F C   1 
ATOM   16520 O O   . ARG F 1 345 ? -0.067  -10.335 162.239 1.00 78.71  ? 364 ARG F O   1 
ATOM   16521 C CB  . ARG F 1 345 ? -0.310  -12.345 159.985 1.00 76.29  ? 364 ARG F CB  1 
ATOM   16522 C CG  . ARG F 1 345 ? -1.798  -12.545 159.695 1.00 79.88  ? 364 ARG F CG  1 
ATOM   16523 C CD  . ARG F 1 345 ? -2.342  -13.874 160.254 1.00 80.70  ? 364 ARG F CD  1 
ATOM   16524 N NE  . ARG F 1 345 ? -3.247  -13.649 161.374 1.00 82.06  ? 364 ARG F NE  1 
ATOM   16525 C CZ  . ARG F 1 345 ? -3.847  -14.620 162.052 1.00 85.24  ? 364 ARG F CZ  1 
ATOM   16526 N NH1 . ARG F 1 345 ? -3.673  -15.894 161.728 1.00 87.55  ? 364 ARG F NH1 1 
ATOM   16527 N NH2 . ARG F 1 345 ? -4.637  -14.302 163.087 1.00 85.96  ? 364 ARG F NH2 1 
ATOM   16528 N N   . ASP F 1 346 ? -1.482  -9.278  160.809 1.00 77.76  ? 365 ASP F N   1 
ATOM   16529 C CA  . ASP F 1 346 ? -2.278  -8.598  161.822 1.00 81.49  ? 365 ASP F CA  1 
ATOM   16530 C C   . ASP F 1 346 ? -3.752  -8.881  161.510 1.00 83.59  ? 365 ASP F C   1 
ATOM   16531 O O   . ASP F 1 346 ? -4.471  -8.020  161.003 1.00 84.11  ? 365 ASP F O   1 
ATOM   16532 C CB  . ASP F 1 346 ? -1.995  -7.091  161.847 1.00 82.49  ? 365 ASP F CB  1 
ATOM   16533 N N   . GLY F 1 347 ? -4.165  -10.105 161.760 1.00 84.37  ? 366 GLY F N   1 
ATOM   16534 C CA  . GLY F 1 347 ? -5.538  -10.555 161.464 1.00 86.41  ? 366 GLY F CA  1 
ATOM   16535 C C   . GLY F 1 347 ? -5.611  -11.139 160.042 1.00 84.36  ? 366 GLY F C   1 
ATOM   16536 O O   . GLY F 1 347 ? -4.957  -12.130 159.749 1.00 82.46  ? 366 GLY F O   1 
ATOM   16537 N N   . TRP F 1 348 ? -6.455  -10.534 159.218 1.00 84.65  ? 367 TRP F N   1 
ATOM   16538 C CA  . TRP F 1 348 ? -6.548  -10.855 157.801 1.00 82.57  ? 367 TRP F CA  1 
ATOM   16539 C C   . TRP F 1 348 ? -5.624  -9.999  156.941 1.00 79.78  ? 367 TRP F C   1 
ATOM   16540 O O   . TRP F 1 348 ? -5.648  -10.112 155.710 1.00 78.12  ? 367 TRP F O   1 
ATOM   16541 C CB  . TRP F 1 348 ? -7.990  -10.682 157.346 1.00 85.36  ? 367 TRP F CB  1 
ATOM   16542 C CG  . TRP F 1 348 ? -8.944  -11.258 158.304 1.00 88.07  ? 367 TRP F CG  1 
ATOM   16543 C CD1 . TRP F 1 348 ? -9.743  -10.576 159.181 1.00 91.90  ? 367 TRP F CD1 1 
ATOM   16544 C CD2 . TRP F 1 348 ? -9.226  -12.649 158.491 1.00 87.66  ? 367 TRP F CD2 1 
ATOM   16545 N NE1 . TRP F 1 348 ? -10.507 -11.469 159.908 1.00 93.85  ? 367 TRP F NE1 1 
ATOM   16546 C CE2 . TRP F 1 348 ? -10.211 -12.744 159.499 1.00 91.08  ? 367 TRP F CE2 1 
ATOM   16547 C CE3 . TRP F 1 348 ? -8.746  -13.819 157.904 1.00 84.82  ? 367 TRP F CE3 1 
ATOM   16548 C CZ2 . TRP F 1 348 ? -10.718 -13.958 159.933 1.00 91.64  ? 367 TRP F CZ2 1 
ATOM   16549 C CZ3 . TRP F 1 348 ? -9.253  -15.024 158.337 1.00 85.35  ? 367 TRP F CZ3 1 
ATOM   16550 C CH2 . TRP F 1 348 ? -10.235 -15.084 159.340 1.00 88.60  ? 367 TRP F CH2 1 
ATOM   16551 N N   . LYS F 1 349 ? -4.833  -9.138  157.559 1.00 81.50  ? 368 LYS F N   1 
ATOM   16552 C CA  . LYS F 1 349 ? -3.885  -8.313  156.835 1.00 79.52  ? 368 LYS F CA  1 
ATOM   16553 C C   . LYS F 1 349 ? -2.540  -9.029  156.832 1.00 76.17  ? 368 LYS F C   1 
ATOM   16554 O O   . LYS F 1 349 ? -2.168  -9.696  157.803 1.00 76.53  ? 368 LYS F O   1 
ATOM   16555 C CB  . LYS F 1 349 ? -3.776  -6.927  157.477 1.00 81.50  ? 368 LYS F CB  1 
ATOM   16556 N N   . LEU F 1 350 ? -1.826  -8.905  155.722 1.00 75.67  ? 369 LEU F N   1 
ATOM   16557 C CA  . LEU F 1 350 ? -0.510  -9.495  155.551 1.00 72.91  ? 369 LEU F CA  1 
ATOM   16558 C C   . LEU F 1 350 ? 0.403   -8.425  154.985 1.00 71.77  ? 369 LEU F C   1 
ATOM   16559 O O   . LEU F 1 350 ? -0.051  -7.537  154.267 1.00 72.24  ? 369 LEU F O   1 
ATOM   16560 C CB  . LEU F 1 350 ? -0.560  -10.692 154.612 1.00 72.17  ? 369 LEU F CB  1 
ATOM   16561 C CG  . LEU F 1 350 ? -1.553  -11.791 155.000 1.00 74.13  ? 369 LEU F CG  1 
ATOM   16562 C CD1 . LEU F 1 350 ? -1.953  -12.598 153.788 1.00 73.38  ? 369 LEU F CD1 1 
ATOM   16563 C CD2 . LEU F 1 350 ? -0.936  -12.682 156.076 1.00 74.48  ? 369 LEU F CD2 1 
ATOM   16564 N N   . SER F 1 351 ? 1.692   -8.512  155.298 1.00 70.85  ? 370 SER F N   1 
ATOM   16565 C CA  . SER F 1 351 ? 2.659   -7.599  154.711 1.00 69.75  ? 370 SER F CA  1 
ATOM   16566 C C   . SER F 1 351 ? 3.970   -8.325  154.457 1.00 67.26  ? 370 SER F C   1 
ATOM   16567 O O   . SER F 1 351 ? 4.258   -9.373  155.051 1.00 66.61  ? 370 SER F O   1 
ATOM   16568 C CB  . SER F 1 351 ? 2.892   -6.377  155.604 1.00 71.07  ? 370 SER F CB  1 
ATOM   16569 O OG  . SER F 1 351 ? 3.463   -6.734  156.846 1.00 71.46  ? 370 SER F OG  1 
ATOM   16570 N N   . ARG F 1 352 ? 4.764   -7.757  153.545 1.00 66.78  ? 371 ARG F N   1 
ATOM   16571 C CA  . ARG F 1 352 ? 6.048   -8.356  153.197 1.00 63.84  ? 371 ARG F CA  1 
ATOM   16572 C C   . ARG F 1 352 ? 6.932   -7.324  152.518 1.00 62.47  ? 371 ARG F C   1 
ATOM   16573 O O   . ARG F 1 352 ? 6.491   -6.641  151.590 1.00 63.14  ? 371 ARG F O   1 
ATOM   16574 C CB  . ARG F 1 352 ? 5.885   -9.573  152.280 1.00 62.87  ? 371 ARG F CB  1 
ATOM   16575 C CG  . ARG F 1 352 ? 7.151   -10.402 152.167 1.00 59.84  ? 371 ARG F CG  1 
ATOM   16576 C CD  . ARG F 1 352 ? 7.302   -11.312 153.367 1.00 59.89  ? 371 ARG F CD  1 
ATOM   16577 N NE  . ARG F 1 352 ? 8.419   -12.232 153.203 1.00 57.31  ? 371 ARG F NE  1 
ATOM   16578 C CZ  . ARG F 1 352 ? 8.404   -13.305 152.424 1.00 56.34  ? 371 ARG F CZ  1 
ATOM   16579 N NH1 . ARG F 1 352 ? 7.334   -13.632 151.724 1.00 57.53  ? 371 ARG F NH1 1 
ATOM   16580 N NH2 . ARG F 1 352 ? 9.486   -14.077 152.361 1.00 54.57  ? 371 ARG F NH2 1 
ATOM   16581 N N   . GLU F 1 353 ? 8.180   -7.243  152.971 1.00 61.04  ? 372 GLU F N   1 
ATOM   16582 C CA  . GLU F 1 353 ? 9.178   -6.365  152.391 1.00 59.66  ? 372 GLU F CA  1 
ATOM   16583 C C   . GLU F 1 353 ? 10.181  -7.179  151.582 1.00 57.24  ? 372 GLU F C   1 
ATOM   16584 O O   . GLU F 1 353 ? 10.725  -8.172  152.072 1.00 56.06  ? 372 GLU F O   1 
ATOM   16585 C CB  . GLU F 1 353 ? 9.938   -5.597  153.483 1.00 60.12  ? 372 GLU F CB  1 
ATOM   16586 C CG  . GLU F 1 353 ? 9.205   -4.456  154.130 1.00 63.87  ? 372 GLU F CG  1 
ATOM   16587 C CD  . GLU F 1 353 ? 9.030   -3.275  153.194 1.00 66.01  ? 372 GLU F CD  1 
ATOM   16588 O OE1 . GLU F 1 353 ? 9.839   -3.169  152.233 1.00 64.23  ? 372 GLU F OE1 1 
ATOM   16589 O OE2 . GLU F 1 353 ? 8.095   -2.445  153.400 1.00 69.48  ? 372 GLU F OE2 1 
ATOM   16590 N N   . TYR F 1 354 ? 10.466  -6.712  150.379 1.00 55.66  ? 373 TYR F N   1 
ATOM   16591 C CA  . TYR F 1 354 ? 11.529  -7.196  149.517 1.00 53.85  ? 373 TYR F CA  1 
ATOM   16592 C C   . TYR F 1 354 ? 12.526  -6.065  149.308 1.00 53.30  ? 373 TYR F C   1 
ATOM   16593 O O   . TYR F 1 354 ? 12.254  -4.903  149.637 1.00 54.83  ? 373 TYR F O   1 
ATOM   16594 C CB  . TYR F 1 354 ? 10.959  -7.654  148.162 1.00 53.96  ? 373 TYR F CB  1 
ATOM   16595 C CG  . TYR F 1 354 ? 10.113  -8.919  148.217 1.00 53.89  ? 373 TYR F CG  1 
ATOM   16596 C CD1 . TYR F 1 354 ? 8.829   -8.911  148.750 1.00 55.72  ? 373 TYR F CD1 1 
ATOM   16597 C CD2 . TYR F 1 354 ? 10.591  -10.104 147.704 1.00 52.58  ? 373 TYR F CD2 1 
ATOM   16598 C CE1 . TYR F 1 354 ? 8.067   -10.038 148.778 1.00 56.19  ? 373 TYR F CE1 1 
ATOM   16599 C CE2 . TYR F 1 354 ? 9.835   -11.241 147.738 1.00 53.18  ? 373 TYR F CE2 1 
ATOM   16600 C CZ  . TYR F 1 354 ? 8.568   -11.207 148.276 1.00 54.61  ? 373 TYR F CZ  1 
ATOM   16601 O OH  . TYR F 1 354 ? 7.798   -12.353 148.304 1.00 55.33  ? 373 TYR F OH  1 
ATOM   16602 N N   . LYS F 1 355 ? 13.673  -6.375  148.697 1.00 55.08  ? 374 LYS F N   1 
ATOM   16603 C CA  . LYS F 1 355 ? 14.658  -5.313  148.465 1.00 54.83  ? 374 LYS F CA  1 
ATOM   16604 C C   . LYS F 1 355 ? 14.047  -4.147  147.699 1.00 53.78  ? 374 LYS F C   1 
ATOM   16605 O O   . LYS F 1 355 ? 14.335  -2.985  147.984 1.00 55.41  ? 374 LYS F O   1 
ATOM   16606 C CB  . LYS F 1 355 ? 15.871  -5.846  147.697 1.00 52.40  ? 374 LYS F CB  1 
ATOM   16607 C CG  . LYS F 1 355 ? 16.867  -6.574  148.550 1.00 54.85  ? 374 LYS F CG  1 
ATOM   16608 C CD  . LYS F 1 355 ? 17.961  -7.281  147.700 1.00 52.34  ? 374 LYS F CD  1 
ATOM   16609 C CE  . LYS F 1 355 ? 19.017  -6.287  147.146 1.00 49.65  ? 374 LYS F CE  1 
ATOM   16610 N NZ  . LYS F 1 355 ? 20.479  -6.730  147.116 1.00 49.61  ? 374 LYS F NZ  1 
ATOM   16611 N N   . HIS F 1 356 ? 13.191  -4.442  146.734 1.00 55.31  ? 375 HIS F N   1 
ATOM   16612 C CA  . HIS F 1 356 ? 12.665  -3.438  145.824 1.00 54.16  ? 375 HIS F CA  1 
ATOM   16613 C C   . HIS F 1 356 ? 11.148  -3.432  145.773 1.00 55.25  ? 375 HIS F C   1 
ATOM   16614 O O   . HIS F 1 356 ? 10.575  -2.965  144.781 1.00 53.71  ? 375 HIS F O   1 
ATOM   16615 C CB  . HIS F 1 356 ? 13.190  -3.655  144.416 1.00 51.39  ? 375 HIS F CB  1 
ATOM   16616 C CG  . HIS F 1 356 ? 14.653  -3.916  144.352 1.00 50.74  ? 375 HIS F CG  1 
ATOM   16617 N ND1 . HIS F 1 356 ? 15.582  -2.985  144.741 1.00 52.06  ? 375 HIS F ND1 1 
ATOM   16618 C CD2 . HIS F 1 356 ? 15.353  -4.994  143.929 1.00 49.08  ? 375 HIS F CD2 1 
ATOM   16619 C CE1 . HIS F 1 356 ? 16.795  -3.464  144.548 1.00 51.20  ? 375 HIS F CE1 1 
ATOM   16620 N NE2 . HIS F 1 356 ? 16.685  -4.688  144.066 1.00 49.37  ? 375 HIS F NE2 1 
ATOM   16621 N N   . ALA F 1 357 ? 10.475  -3.954  146.795 1.00 54.67  ? 376 ALA F N   1 
ATOM   16622 C CA  . ALA F 1 357 ? 9.024   -3.864  146.813 1.00 55.71  ? 376 ALA F CA  1 
ATOM   16623 C C   . ALA F 1 357 ? 8.491   -3.935  148.232 1.00 60.04  ? 376 ALA F C   1 
ATOM   16624 O O   . ALA F 1 357 ? 9.138   -4.477  149.129 1.00 61.74  ? 376 ALA F O   1 
ATOM   16625 C CB  . ALA F 1 357 ? 8.401   -4.967  145.947 1.00 52.75  ? 376 ALA F CB  1 
ATOM   16626 N N   . SER F 1 358 ? 7.312   -3.344  148.430 1.00 57.58  ? 377 SER F N   1 
ATOM   16627 C CA  . SER F 1 358 ? 6.536   -3.471  149.656 1.00 61.67  ? 377 SER F CA  1 
ATOM   16628 C C   . SER F 1 358 ? 5.172   -4.016  149.256 1.00 60.78  ? 377 SER F C   1 
ATOM   16629 O O   . SER F 1 358 ? 4.539   -3.510  148.328 1.00 59.48  ? 377 SER F O   1 
ATOM   16630 C CB  . SER F 1 358 ? 6.399   -2.144  150.411 1.00 66.15  ? 377 SER F CB  1 
ATOM   16631 O OG  . SER F 1 358 ? 7.637   -1.680  150.959 1.00 68.16  ? 377 SER F OG  1 
ATOM   16632 N N   . VAL F 1 359 ? 4.745   -5.083  149.912 1.00 65.05  ? 378 VAL F N   1 
ATOM   16633 C CA  . VAL F 1 359 ? 3.541   -5.818  149.541 1.00 64.13  ? 378 VAL F CA  1 
ATOM   16634 C C   . VAL F 1 359 ? 2.595   -5.787  150.726 1.00 68.66  ? 378 VAL F C   1 
ATOM   16635 O O   . VAL F 1 359 ? 2.999   -6.083  151.857 1.00 71.59  ? 378 VAL F O   1 
ATOM   16636 C CB  . VAL F 1 359 ? 3.864   -7.268  149.146 1.00 61.25  ? 378 VAL F CB  1 
ATOM   16637 C CG1 . VAL F 1 359 ? 2.602   -8.014  148.787 1.00 60.59  ? 378 VAL F CG1 1 
ATOM   16638 C CG2 . VAL F 1 359 ? 4.832   -7.278  147.992 1.00 57.67  ? 378 VAL F CG2 1 
ATOM   16639 N N   . ARG F 1 360 ? 1.348   -5.428  150.471 1.00 64.84  ? 379 ARG F N   1 
ATOM   16640 C CA  . ARG F 1 360 ? 0.339   -5.417  151.513 1.00 68.91  ? 379 ARG F CA  1 
ATOM   16641 C C   . ARG F 1 360 ? -0.910  -6.041  150.931 1.00 67.46  ? 379 ARG F C   1 
ATOM   16642 O O   . ARG F 1 360 ? -1.172  -5.916  149.737 1.00 64.74  ? 379 ARG F O   1 
ATOM   16643 C CB  . ARG F 1 360 ? 0.063   -4.006  152.008 1.00 73.64  ? 379 ARG F CB  1 
ATOM   16644 C CG  . ARG F 1 360 ? -0.139  -3.922  153.512 1.00 80.39  ? 379 ARG F CG  1 
ATOM   16645 C CD  . ARG F 1 360 ? 0.603   -2.716  154.124 1.00 85.33  ? 379 ARG F CD  1 
ATOM   16646 N NE  . ARG F 1 360 ? 0.596   -2.780  155.583 1.00 91.01  ? 379 ARG F NE  1 
ATOM   16647 C CZ  . ARG F 1 360 ? 1.661   -3.012  156.343 1.00 93.67  ? 379 ARG F CZ  1 
ATOM   16648 N NH1 . ARG F 1 360 ? 2.874   -3.119  155.825 1.00 91.08  ? 379 ARG F NH1 1 
ATOM   16649 N NH2 . ARG F 1 360 ? 1.502   -3.140  157.658 1.00 98.64  ? 379 ARG F NH2 1 
ATOM   16650 N N   . VAL F 1 361 ? -1.658  -6.750  151.770 1.00 71.81  ? 380 VAL F N   1 
ATOM   16651 C CA  . VAL F 1 361 ? -2.917  -7.337  151.339 1.00 71.23  ? 380 VAL F CA  1 
ATOM   16652 C C   . VAL F 1 361 ? -3.781  -7.567  152.567 1.00 75.31  ? 380 VAL F C   1 
ATOM   16653 O O   . VAL F 1 361 ? -3.279  -7.837  153.663 1.00 78.12  ? 380 VAL F O   1 
ATOM   16654 C CB  . VAL F 1 361 ? -2.699  -8.650  150.538 1.00 68.04  ? 380 VAL F CB  1 
ATOM   16655 C CG1 . VAL F 1 361 ? -1.852  -9.640  151.336 1.00 68.56  ? 380 VAL F CG1 1 
ATOM   16656 C CG2 . VAL F 1 361 ? -4.067  -9.267  150.126 1.00 68.13  ? 380 VAL F CG2 1 
ATOM   16657 N N   . ASP F 1 362 ? -5.094  -7.448  152.369 1.00 75.61  ? 381 ASP F N   1 
ATOM   16658 C CA  . ASP F 1 362 ? -6.108  -7.672  153.394 1.00 79.42  ? 381 ASP F CA  1 
ATOM   16659 C C   . ASP F 1 362 ? -7.107  -8.667  152.824 1.00 77.73  ? 381 ASP F C   1 
ATOM   16660 O O   . ASP F 1 362 ? -7.888  -8.324  151.923 1.00 76.60  ? 381 ASP F O   1 
ATOM   16661 C CB  . ASP F 1 362 ? -6.824  -6.381  153.796 1.00 82.75  ? 381 ASP F CB  1 
ATOM   16662 C CG  . ASP F 1 362 ? -7.775  -6.587  154.972 1.00 87.56  ? 381 ASP F CG  1 
ATOM   16663 O OD1 . ASP F 1 362 ? -7.455  -7.420  155.852 1.00 89.49  ? 381 ASP F OD1 1 
ATOM   16664 O OD2 . ASP F 1 362 ? -8.840  -5.929  155.011 1.00 89.47  ? 381 ASP F OD2 1 
ATOM   16665 N N   . LEU F 1 363 ? -7.096  -9.882  153.364 1.00 80.71  ? 382 LEU F N   1 
ATOM   16666 C CA  . LEU F 1 363 ? -7.939  -10.937 152.820 1.00 79.53  ? 382 LEU F CA  1 
ATOM   16667 C C   . LEU F 1 363 ? -9.426  -10.658 153.046 1.00 82.71  ? 382 LEU F C   1 
ATOM   16668 O O   . LEU F 1 363 ? -10.261 -11.100 152.246 1.00 81.81  ? 382 LEU F O   1 
ATOM   16669 C CB  . LEU F 1 363 ? -7.498  -12.276 153.431 1.00 79.47  ? 382 LEU F CB  1 
ATOM   16670 C CG  . LEU F 1 363 ? -6.012  -12.628 153.216 1.00 76.31  ? 382 LEU F CG  1 
ATOM   16671 C CD1 . LEU F 1 363 ? -5.587  -13.917 153.913 1.00 76.47  ? 382 LEU F CD1 1 
ATOM   16672 C CD2 . LEU F 1 363 ? -5.684  -12.720 151.718 1.00 71.82  ? 382 LEU F CD2 1 
ATOM   16673 N N   . GLU F 1 364 ? -9.772  -9.904  154.099 1.00 79.86  ? 383 GLU F N   1 
ATOM   16674 C CA  . GLU F 1 364 ? -11.173 -9.656  154.433 1.00 83.28  ? 383 GLU F CA  1 
ATOM   16675 C C   . GLU F 1 364 ? -11.806 -8.622  153.508 1.00 82.28  ? 383 GLU F C   1 
ATOM   16676 O O   . GLU F 1 364 ? -12.986 -8.731  153.164 1.00 82.56  ? 383 GLU F O   1 
ATOM   16677 C CB  . GLU F 1 364 ? -11.298 -9.196  155.887 1.00 87.88  ? 383 GLU F CB  1 
ATOM   16678 N N   . SER F 1 365 ? -11.049 -7.609  153.097 1.00 84.19  ? 384 SER F N   1 
ATOM   16679 C CA  . SER F 1 365 ? -11.560 -6.635  152.147 1.00 83.24  ? 384 SER F CA  1 
ATOM   16680 C C   . SER F 1 365 ? -11.075 -6.876  150.725 1.00 79.32  ? 384 SER F C   1 
ATOM   16681 O O   . SER F 1 365 ? -11.635 -6.280  149.801 1.00 78.54  ? 384 SER F O   1 
ATOM   16682 C CB  . SER F 1 365 ? -11.164 -5.212  152.560 1.00 84.89  ? 384 SER F CB  1 
ATOM   16683 O OG  . SER F 1 365 ? -9.755  -5.062  152.590 1.00 83.24  ? 384 SER F OG  1 
ATOM   16684 N N   . LYS F 1 366 ? -10.040 -7.708  150.528 1.00 82.36  ? 385 LYS F N   1 
ATOM   16685 C CA  . LYS F 1 366 ? -9.456  -7.954  149.201 1.00 79.39  ? 385 LYS F CA  1 
ATOM   16686 C C   . LYS F 1 366 ? -8.823  -6.678  148.609 1.00 78.11  ? 385 LYS F C   1 
ATOM   16687 O O   . LYS F 1 366 ? -8.564  -6.601  147.406 1.00 75.96  ? 385 LYS F O   1 
ATOM   16688 C CB  . LYS F 1 366 ? -10.537 -8.580  148.290 1.00 79.97  ? 385 LYS F CB  1 
ATOM   16689 C CG  . LYS F 1 366 ? -10.403 -8.492  146.749 1.00 81.68  ? 385 LYS F CG  1 
ATOM   16690 C CD  . LYS F 1 366 ? -10.947 -7.204  146.106 1.00 83.89  ? 385 LYS F CD  1 
ATOM   16691 C CE  . LYS F 1 366 ? -12.307 -6.744  146.625 1.00 86.90  ? 385 LYS F CE  1 
ATOM   16692 N NZ  . LYS F 1 366 ? -12.797 -5.518  145.892 1.00 90.28  ? 385 LYS F NZ  1 
ATOM   16693 N N   . GLU F 1 367 ? -8.501  -5.684  149.449 1.00 78.42  ? 386 GLU F N   1 
ATOM   16694 C CA  . GLU F 1 367 ? -7.698  -4.532  149.042 1.00 77.97  ? 386 GLU F CA  1 
ATOM   16695 C C   . GLU F 1 367 ? -6.215  -4.874  149.153 1.00 75.05  ? 386 GLU F C   1 
ATOM   16696 O O   . GLU F 1 367 ? -5.799  -5.600  150.065 1.00 75.56  ? 386 GLU F O   1 
ATOM   16697 C CB  . GLU F 1 367 ? -8.016  -3.312  149.910 1.00 82.58  ? 386 GLU F CB  1 
ATOM   16698 N N   . ALA F 1 368 ? -5.415  -4.353  148.221 1.00 75.96  ? 387 ALA F N   1 
ATOM   16699 C CA  . ALA F 1 368 ? -4.003  -4.714  148.153 1.00 73.40  ? 387 ALA F CA  1 
ATOM   16700 C C   . ALA F 1 368 ? -3.205  -3.609  147.474 1.00 72.63  ? 387 ALA F C   1 
ATOM   16701 O O   . ALA F 1 368 ? -3.696  -2.955  146.551 1.00 72.55  ? 387 ALA F O   1 
ATOM   16702 C CB  . ALA F 1 368 ? -3.804  -6.027  147.388 1.00 70.14  ? 387 ALA F CB  1 
ATOM   16703 N N   . GLU F 1 369 ? -1.964  -3.408  147.941 1.00 69.71  ? 388 GLU F N   1 
ATOM   16704 C CA  . GLU F 1 369 ? -1.040  -2.427  147.381 1.00 69.19  ? 388 GLU F CA  1 
ATOM   16705 C C   . GLU F 1 369 ? 0.315   -3.095  147.202 1.00 65.85  ? 388 GLU F C   1 
ATOM   16706 O O   . GLU F 1 369 ? 0.756   -3.851  148.074 1.00 66.77  ? 388 GLU F O   1 
ATOM   16707 C CB  . GLU F 1 369 ? -0.914  -1.191  148.287 1.00 74.39  ? 388 GLU F CB  1 
ATOM   16708 N N   . ILE F 1 370 ? 0.961   -2.845  146.065 1.00 66.98  ? 389 ILE F N   1 
ATOM   16709 C CA  . ILE F 1 370 ? 2.333   -3.286  145.820 1.00 64.74  ? 389 ILE F CA  1 
ATOM   16710 C C   . ILE F 1 370 ? 3.140   -2.077  145.377 1.00 64.79  ? 389 ILE F C   1 
ATOM   16711 O O   . ILE F 1 370 ? 2.985   -1.613  144.239 1.00 63.56  ? 389 ILE F O   1 
ATOM   16712 C CB  . ILE F 1 370 ? 2.428   -4.396  144.763 1.00 61.09  ? 389 ILE F CB  1 
ATOM   16713 C CG1 . ILE F 1 370 ? 1.708   -5.634  145.278 1.00 61.76  ? 389 ILE F CG1 1 
ATOM   16714 C CG2 . ILE F 1 370 ? 3.912   -4.631  144.400 1.00 59.18  ? 389 ILE F CG2 1 
ATOM   16715 C CD1 . ILE F 1 370 ? 0.910   -6.346  144.218 1.00 60.37  ? 389 ILE F CD1 1 
ATOM   16716 N N   . ARG F 1 371 ? 4.023   -1.583  146.252 1.00 62.85  ? 390 ARG F N   1 
ATOM   16717 C CA  . ARG F 1 371 ? 4.848   -0.418  145.960 1.00 63.36  ? 390 ARG F CA  1 
ATOM   16718 C C   . ARG F 1 371 ? 6.242   -0.890  145.544 1.00 59.94  ? 390 ARG F C   1 
ATOM   16719 O O   . ARG F 1 371 ? 7.016   -1.383  146.369 1.00 61.04  ? 390 ARG F O   1 
ATOM   16720 C CB  . ARG F 1 371 ? 4.917   0.522   147.166 1.00 68.72  ? 390 ARG F CB  1 
ATOM   16721 N N   . TRP F 1 372 ? 6.563   -0.712  144.266 1.00 65.12  ? 391 TRP F N   1 
ATOM   16722 C CA  . TRP F 1 372 ? 7.892   -0.990  143.743 1.00 62.38  ? 391 TRP F CA  1 
ATOM   16723 C C   . TRP F 1 372 ? 8.831   0.167   144.047 1.00 64.13  ? 391 TRP F C   1 
ATOM   16724 O O   . TRP F 1 372 ? 8.443   1.329   143.988 1.00 66.40  ? 391 TRP F O   1 
ATOM   16725 C CB  . TRP F 1 372 ? 7.784   -1.257  142.242 1.00 58.78  ? 391 TRP F CB  1 
ATOM   16726 C CG  . TRP F 1 372 ? 6.676   -2.273  141.960 1.00 57.80  ? 391 TRP F CG  1 
ATOM   16727 C CD1 . TRP F 1 372 ? 5.364   -2.001  141.747 1.00 58.96  ? 391 TRP F CD1 1 
ATOM   16728 C CD2 . TRP F 1 372 ? 6.798   -3.713  141.915 1.00 55.40  ? 391 TRP F CD2 1 
ATOM   16729 N NE1 . TRP F 1 372 ? 4.660   -3.173  141.561 1.00 58.02  ? 391 TRP F NE1 1 
ATOM   16730 C CE2 . TRP F 1 372 ? 5.516   -4.233  141.656 1.00 55.56  ? 391 TRP F CE2 1 
ATOM   16731 C CE3 . TRP F 1 372 ? 7.863   -4.595  142.057 1.00 53.46  ? 391 TRP F CE3 1 
ATOM   16732 C CZ2 . TRP F 1 372 ? 5.265   -5.590  141.527 1.00 53.90  ? 391 TRP F CZ2 1 
ATOM   16733 C CZ3 . TRP F 1 372 ? 7.621   -5.954  141.934 1.00 51.86  ? 391 TRP F CZ3 1 
ATOM   16734 C CH2 . TRP F 1 372 ? 6.320   -6.442  141.670 1.00 52.12  ? 391 TRP F CH2 1 
ATOM   16735 N N   . ARG F 1 373 ? 10.061  -0.161  144.407 1.00 59.76  ? 392 ARG F N   1 
ATOM   16736 C CA  . ARG F 1 373 ? 11.005  0.800   144.963 1.00 61.97  ? 392 ARG F CA  1 
ATOM   16737 C C   . ARG F 1 373 ? 12.409  0.376   144.550 1.00 59.43  ? 392 ARG F C   1 
ATOM   16738 O O   . ARG F 1 373 ? 12.830  0.657   143.436 1.00 57.12  ? 392 ARG F O   1 
ATOM   16739 C CB  . ARG F 1 373 ? 10.898  0.870   146.486 1.00 66.92  ? 392 ARG F CB  1 
HETATM 16740 C C1  . EDO G 2 .   ? 8.714   -2.531  74.799  1.00 37.35  ? 401 EDO A C1  1 
HETATM 16741 O O1  . EDO G 2 .   ? 9.977   -1.956  75.224  1.00 34.77  ? 401 EDO A O1  1 
HETATM 16742 C C2  . EDO G 2 .   ? 7.725   -2.120  75.892  1.00 36.19  ? 401 EDO A C2  1 
HETATM 16743 O O2  . EDO G 2 .   ? 8.373   -2.431  77.137  1.00 36.43  ? 401 EDO A O2  1 
HETATM 16744 C C1  . EDO H 2 .   ? 22.270  11.751  109.576 1.00 40.12  ? 401 EDO B C1  1 
HETATM 16745 O O1  . EDO H 2 .   ? 23.513  11.079  109.869 1.00 37.54  ? 401 EDO B O1  1 
HETATM 16746 C C2  . EDO H 2 .   ? 21.589  12.024  110.919 1.00 38.96  ? 401 EDO B C2  1 
HETATM 16747 O O2  . EDO H 2 .   ? 21.523  10.735  111.546 1.00 39.20  ? 401 EDO B O2  1 
HETATM 16748 C C1  . EDO I 2 .   ? 45.918  -2.039  151.733 1.00 46.22  ? 401 EDO C C1  1 
HETATM 16749 O O1  . EDO I 2 .   ? 47.144  -1.271  151.638 1.00 43.64  ? 401 EDO C O1  1 
HETATM 16750 C C2  . EDO I 2 .   ? 45.327  -1.788  153.132 1.00 45.06  ? 401 EDO C C2  1 
HETATM 16751 O O2  . EDO I 2 .   ? 46.396  -1.992  154.077 1.00 45.30  ? 401 EDO C O2  1 
HETATM 16752 O O   . HOH J 3 .   ? 22.910  -8.489  67.239  1.00 35.99  ? 501 HOH A O   1 
HETATM 16753 O O   . HOH J 3 .   ? 21.092  -21.114 75.159  1.00 35.91  ? 502 HOH A O   1 
HETATM 16754 O O   . HOH J 3 .   ? 24.780  -8.583  84.968  1.00 36.48  ? 503 HOH A O   1 
HETATM 16755 O O   . HOH J 3 .   ? -5.358  5.377   73.375  1.00 29.47  ? 504 HOH A O   1 
HETATM 16756 O O   . HOH J 3 .   ? 3.059   5.907   66.030  1.00 31.73  ? 505 HOH A O   1 
HETATM 16757 O O   . HOH J 3 .   ? 35.322  -0.338  78.653  1.00 45.79  ? 506 HOH A O   1 
HETATM 16758 O O   . HOH J 3 .   ? 26.459  -6.551  85.820  1.00 39.65  ? 507 HOH A O   1 
HETATM 16759 O O   . HOH J 3 .   ? -0.407  -5.657  50.236  1.00 35.89  ? 508 HOH A O   1 
HETATM 16760 O O   . HOH J 3 .   ? 7.770   -11.752 52.552  1.00 34.83  ? 509 HOH A O   1 
HETATM 16761 O O   . HOH J 3 .   ? -12.047 6.019   75.247  1.00 38.08  ? 510 HOH A O   1 
HETATM 16762 O O   . HOH J 3 .   ? 21.786  -22.243 85.128  1.00 32.44  ? 511 HOH A O   1 
HETATM 16763 O O   . HOH J 3 .   ? 0.888   -0.291  74.775  1.00 30.45  ? 512 HOH A O   1 
HETATM 16764 O O   . HOH J 3 .   ? -0.748  -21.954 75.362  1.00 35.58  ? 513 HOH A O   1 
HETATM 16765 O O   . HOH J 3 .   ? -5.235  -6.956  92.429  1.00 29.31  ? 514 HOH A O   1 
HETATM 16766 O O   . HOH J 3 .   ? 28.979  -20.125 79.280  1.00 37.71  ? 515 HOH A O   1 
HETATM 16767 O O   . HOH J 3 .   ? -4.669  -19.378 65.109  1.00 37.66  ? 516 HOH A O   1 
HETATM 16768 O O   . HOH J 3 .   ? -5.366  -1.757  47.544  1.00 41.31  ? 517 HOH A O   1 
HETATM 16769 O O   . HOH J 3 .   ? 25.722  0.276   81.026  1.00 39.45  ? 518 HOH A O   1 
HETATM 16770 O O   . HOH J 3 .   ? -4.068  -16.433 60.965  1.00 37.83  ? 519 HOH A O   1 
HETATM 16771 O O   . HOH J 3 .   ? 18.107  -12.939 96.860  1.00 35.27  ? 520 HOH A O   1 
HETATM 16772 O O   . HOH J 3 .   ? 11.358  -27.058 67.985  1.00 36.17  ? 521 HOH A O   1 
HETATM 16773 O O   . HOH J 3 .   ? -2.476  -13.933 64.406  1.00 29.40  ? 522 HOH A O   1 
HETATM 16774 O O   . HOH J 3 .   ? 24.687  2.853   85.224  1.00 50.87  ? 523 HOH A O   1 
HETATM 16775 O O   . HOH J 3 .   ? 1.262   -25.009 79.108  1.00 29.37  ? 524 HOH A O   1 
HETATM 16776 O O   . HOH J 3 .   ? -4.625  -22.341 84.279  1.00 40.17  ? 525 HOH A O   1 
HETATM 16777 O O   . HOH J 3 .   ? 8.188   10.889  69.977  1.00 33.99  ? 526 HOH A O   1 
HETATM 16778 O O   . HOH J 3 .   ? 12.920  12.920  55.971  1.00 39.23  ? 527 HOH A O   1 
HETATM 16779 O O   . HOH J 3 .   ? -0.741  15.473  75.919  1.00 31.10  ? 528 HOH A O   1 
HETATM 16780 O O   . HOH J 3 .   ? 29.386  -13.940 83.128  1.00 40.45  ? 529 HOH A O   1 
HETATM 16781 O O   . HOH J 3 .   ? -6.732  3.589   79.948  1.00 29.56  ? 530 HOH A O   1 
HETATM 16782 O O   . HOH J 3 .   ? 6.016   10.990  46.496  1.00 45.68  ? 531 HOH A O   1 
HETATM 16783 O O   . HOH J 3 .   ? -12.416 13.485  78.819  1.00 41.59  ? 532 HOH A O   1 
HETATM 16784 O O   . HOH J 3 .   ? -0.117  17.266  73.861  1.00 32.90  ? 533 HOH A O   1 
HETATM 16785 O O   . HOH K 3 .   ? 30.891  6.127   100.293 1.00 38.99  ? 501 HOH B O   1 
HETATM 16786 O O   . HOH K 3 .   ? 39.162  -14.808 104.821 1.00 56.19  ? 502 HOH B O   1 
HETATM 16787 O O   . HOH K 3 .   ? 0.208   2.659   108.907 1.00 46.07  ? 503 HOH B O   1 
HETATM 16788 O O   . HOH K 3 .   ? 27.026  -5.280  93.536  1.00 33.24  ? 504 HOH B O   1 
HETATM 16789 O O   . HOH K 3 .   ? 23.596  13.303  102.614 1.00 34.56  ? 505 HOH B O   1 
HETATM 16790 O O   . HOH K 3 .   ? 24.727  24.765  105.596 1.00 36.52  ? 506 HOH B O   1 
HETATM 16791 O O   . HOH K 3 .   ? 22.683  -6.377  118.921 1.00 35.97  ? 507 HOH B O   1 
HETATM 16792 O O   . HOH K 3 .   ? 5.968   4.253   115.326 1.00 37.52  ? 508 HOH B O   1 
HETATM 16793 O O   . HOH K 3 .   ? 27.086  -7.337  112.302 1.00 34.19  ? 509 HOH B O   1 
HETATM 16794 O O   . HOH K 3 .   ? 1.796   17.345  123.228 1.00 40.89  ? 510 HOH B O   1 
HETATM 16795 O O   . HOH K 3 .   ? 26.658  -3.861  117.890 1.00 38.40  ? 511 HOH B O   1 
HETATM 16796 O O   . HOH K 3 .   ? 22.207  35.451  108.098 1.00 34.37  ? 512 HOH B O   1 
HETATM 16797 O O   . HOH K 3 .   ? 32.288  24.148  110.790 1.00 34.62  ? 513 HOH B O   1 
HETATM 16798 O O   . HOH K 3 .   ? 3.422   -5.191  110.326 1.00 41.80  ? 514 HOH B O   1 
HETATM 16799 O O   . HOH K 3 .   ? 16.484  -4.580  93.930  1.00 35.76  ? 515 HOH B O   1 
HETATM 16800 O O   . HOH K 3 .   ? 18.772  18.563  112.364 1.00 33.51  ? 516 HOH B O   1 
HETATM 16801 O O   . HOH K 3 .   ? 9.142   16.570  93.327  1.00 31.57  ? 517 HOH B O   1 
HETATM 16802 O O   . HOH K 3 .   ? 25.158  28.904  127.249 1.00 40.81  ? 518 HOH B O   1 
HETATM 16803 O O   . HOH K 3 .   ? 9.454   32.096  104.741 1.00 37.32  ? 519 HOH B O   1 
HETATM 16804 O O   . HOH K 3 .   ? 8.627   8.865   94.907  1.00 34.60  ? 520 HOH B O   1 
HETATM 16805 O O   . HOH K 3 .   ? 19.573  30.985  116.534 1.00 38.24  ? 521 HOH B O   1 
HETATM 16806 O O   . HOH K 3 .   ? 14.949  33.235  88.241  1.00 44.49  ? 522 HOH B O   1 
HETATM 16807 O O   . HOH K 3 .   ? 27.563  20.883  99.561  1.00 38.45  ? 523 HOH B O   1 
HETATM 16808 O O   . HOH K 3 .   ? 19.466  -0.229  112.505 1.00 32.17  ? 524 HOH B O   1 
HETATM 16809 O O   . HOH K 3 .   ? 7.364   24.408  106.040 1.00 35.13  ? 525 HOH B O   1 
HETATM 16810 O O   . HOH K 3 .   ? 28.053  6.082   114.463 1.00 36.59  ? 526 HOH B O   1 
HETATM 16811 O O   . HOH K 3 .   ? 31.057  15.999  102.971 1.00 40.39  ? 527 HOH B O   1 
HETATM 16812 O O   . HOH K 3 .   ? 29.651  -7.677  112.979 1.00 35.72  ? 528 HOH B O   1 
HETATM 16813 O O   . HOH K 3 .   ? 0.127   2.838   123.259 1.00 41.65  ? 529 HOH B O   1 
HETATM 16814 O O   . HOH K 3 .   ? 31.476  25.406  127.682 1.00 41.82  ? 530 HOH B O   1 
HETATM 16815 O O   . HOH K 3 .   ? 18.732  2.675   113.844 1.00 33.59  ? 531 HOH B O   1 
HETATM 16816 O O   . HOH K 3 .   ? 2.729   8.988   103.950 1.00 36.21  ? 532 HOH B O   1 
HETATM 16817 O O   . HOH K 3 .   ? 35.115  -11.241 99.061  1.00 36.82  ? 533 HOH B O   1 
HETATM 16818 O O   . HOH K 3 .   ? 25.684  15.845  101.542 1.00 36.66  ? 534 HOH B O   1 
HETATM 16819 O O   . HOH K 3 .   ? 24.946  6.239   110.043 1.00 33.70  ? 535 HOH B O   1 
HETATM 16820 O O   . HOH K 3 .   ? 11.203  -10.600 112.482 1.00 37.59  ? 536 HOH B O   1 
HETATM 16821 O O   . HOH K 3 .   ? 21.326  -15.029 102.523 1.00 33.59  ? 537 HOH B O   1 
HETATM 16822 O O   . HOH K 3 .   ? 15.222  -11.122 102.049 1.00 34.30  ? 538 HOH B O   1 
HETATM 16823 O O   . HOH K 3 .   ? 25.261  -5.420  91.501  1.00 38.43  ? 539 HOH B O   1 
HETATM 16824 O O   . HOH K 3 .   ? 22.832  25.130  85.541  1.00 44.96  ? 540 HOH B O   1 
HETATM 16825 O O   . HOH K 3 .   ? 32.507  13.760  106.861 1.00 43.44  ? 541 HOH B O   1 
HETATM 16826 O O   . HOH K 3 .   ? 25.325  33.690  105.913 1.00 40.09  ? 542 HOH B O   1 
HETATM 16827 O O   . HOH K 3 .   ? 24.590  18.614  122.574 1.00 44.44  ? 543 HOH B O   1 
HETATM 16828 O O   . HOH K 3 .   ? 16.199  -1.572  93.080  1.00 39.46  ? 544 HOH B O   1 
HETATM 16829 O O   . HOH K 3 .   ? 10.517  26.728  88.872  1.00 41.57  ? 545 HOH B O   1 
HETATM 16830 O O   . HOH K 3 .   ? 36.903  -11.469 97.056  1.00 40.94  ? 546 HOH B O   1 
HETATM 16831 O O   . HOH K 3 .   ? 28.961  -5.164  119.640 1.00 38.81  ? 547 HOH B O   1 
HETATM 16832 O O   . HOH L 3 .   ? 42.726  -29.150 143.031 1.00 48.28  ? 501 HOH C O   1 
HETATM 16833 O O   . HOH L 3 .   ? 46.630  -24.895 164.320 1.00 50.58  ? 502 HOH C O   1 
HETATM 16834 O O   . HOH L 3 .   ? 32.880  -4.660  128.821 1.00 42.77  ? 503 HOH C O   1 
HETATM 16835 O O   . HOH L 3 .   ? 33.173  0.540   153.466 1.00 36.39  ? 504 HOH C O   1 
HETATM 16836 O O   . HOH L 3 .   ? 40.638  -17.873 140.610 1.00 41.63  ? 505 HOH C O   1 
HETATM 16837 O O   . HOH L 3 .   ? 32.753  -19.651 153.309 1.00 44.83  ? 506 HOH C O   1 
HETATM 16838 O O   . HOH L 3 .   ? 46.319  -1.536  144.337 1.00 40.10  ? 507 HOH C O   1 
HETATM 16839 O O   . HOH L 3 .   ? 52.145  -26.114 143.771 1.00 50.65  ? 508 HOH C O   1 
HETATM 16840 O O   . HOH L 3 .   ? 40.984  -17.158 161.183 1.00 41.76  ? 509 HOH C O   1 
HETATM 16841 O O   . HOH L 3 .   ? 37.013  -21.534 153.462 1.00 40.72  ? 510 HOH C O   1 
HETATM 16842 O O   . HOH L 3 .   ? 31.685  5.907   152.991 1.00 38.89  ? 511 HOH C O   1 
HETATM 16843 O O   . HOH L 3 .   ? 49.008  5.627   143.150 1.00 42.34  ? 512 HOH C O   1 
HETATM 16844 O O   . HOH L 3 .   ? 38.265  0.217   153.195 1.00 39.75  ? 513 HOH C O   1 
HETATM 16845 O O   . HOH L 3 .   ? 38.265  6.689   144.050 1.00 37.29  ? 514 HOH C O   1 
HETATM 16846 O O   . HOH L 3 .   ? 46.433  -26.193 146.954 1.00 45.72  ? 515 HOH C O   1 
HETATM 16847 O O   . HOH L 3 .   ? 26.931  -0.512  127.493 1.00 44.69  ? 516 HOH C O   1 
HETATM 16848 O O   . HOH L 3 .   ? 58.055  -0.942  152.053 1.00 52.96  ? 517 HOH C O   1 
HETATM 16849 O O   . HOH L 3 .   ? 19.642  -8.513  136.090 1.00 45.05  ? 518 HOH C O   1 
HETATM 16850 O O   . HOH L 3 .   ? 45.809  1.061   142.400 1.00 39.02  ? 519 HOH C O   1 
HETATM 16851 O O   . HOH L 3 .   ? 35.173  -7.117  171.459 1.00 47.23  ? 520 HOH C O   1 
HETATM 16852 O O   . HOH L 3 .   ? 48.011  13.623  132.544 1.00 43.61  ? 521 HOH C O   1 
HETATM 16853 O O   . HOH L 3 .   ? 59.028  -12.673 170.807 1.00 51.27  ? 522 HOH C O   1 
HETATM 16854 O O   . HOH L 3 .   ? 31.942  3.870   159.273 1.00 37.78  ? 523 HOH C O   1 
HETATM 16855 O O   . HOH L 3 .   ? 31.143  12.499  142.509 1.00 34.08  ? 524 HOH C O   1 
HETATM 16856 O O   . HOH L 3 .   ? 28.876  -16.143 142.024 1.00 35.67  ? 525 HOH C O   1 
HETATM 16857 O O   . HOH L 3 .   ? 35.480  -1.236  154.243 1.00 37.90  ? 526 HOH C O   1 
HETATM 16858 O O   . HOH L 3 .   ? 37.461  11.897  125.026 1.00 42.93  ? 527 HOH C O   1 
HETATM 16859 O O   . HOH L 3 .   ? 47.967  11.243  140.504 1.00 45.77  ? 528 HOH C O   1 
HETATM 16860 O O   . HOH L 3 .   ? 43.651  -19.656 141.700 1.00 44.91  ? 529 HOH C O   1 
HETATM 16861 O O   . HOH L 3 .   ? 48.277  -27.443 155.091 1.00 44.13  ? 530 HOH C O   1 
HETATM 16862 O O   . HOH L 3 .   ? 17.069  1.602   139.181 1.00 49.97  ? 531 HOH C O   1 
HETATM 16863 O O   . HOH L 3 .   ? 51.384  -8.772  158.940 1.00 45.50  ? 532 HOH C O   1 
HETATM 16864 O O   . HOH M 3 .   ? 59.554  -29.438 118.452 1.00 65.62  ? 401 HOH D O   1 
HETATM 16865 O O   . HOH M 3 .   ? 41.552  -42.052 127.350 1.00 33.93  ? 402 HOH D O   1 
HETATM 16866 O O   . HOH M 3 .   ? 60.647  -55.617 145.119 1.00 49.54  ? 403 HOH D O   1 
HETATM 16867 O O   . HOH M 3 .   ? 38.560  -47.462 134.006 1.00 36.01  ? 404 HOH D O   1 
HETATM 16868 O O   . HOH M 3 .   ? 37.975  -45.360 130.763 1.00 33.56  ? 405 HOH D O   1 
HETATM 16869 O O   . HOH M 3 .   ? 29.076  -37.713 105.284 1.00 51.70  ? 406 HOH D O   1 
HETATM 16870 O O   . HOH M 3 .   ? 39.966  -43.531 129.412 1.00 32.91  ? 407 HOH D O   1 
HETATM 16871 O O   . HOH M 3 .   ? 35.470  -41.616 131.887 1.00 37.62  ? 408 HOH D O   1 
HETATM 16872 O O   . HOH M 3 .   ? 26.537  -28.582 109.945 1.00 51.43  ? 409 HOH D O   1 
HETATM 16873 O O   . HOH M 3 .   ? 47.901  -29.352 142.566 1.00 42.64  ? 410 HOH D O   1 
HETATM 16874 O O   . HOH M 3 .   ? 52.635  -62.065 130.951 1.00 42.98  ? 411 HOH D O   1 
HETATM 16875 O O   . HOH M 3 .   ? 50.507  -68.064 133.040 1.00 45.06  ? 412 HOH D O   1 
HETATM 16876 O O   . HOH M 3 .   ? 36.172  -45.852 114.503 1.00 46.73  ? 413 HOH D O   1 
HETATM 16877 O O   . HOH M 3 .   ? 42.925  -44.490 138.909 1.00 37.35  ? 414 HOH D O   1 
HETATM 16878 O O   . HOH M 3 .   ? 42.881  -59.087 126.856 1.00 38.23  ? 415 HOH D O   1 
HETATM 16879 O O   . HOH M 3 .   ? 48.504  -64.713 139.508 1.00 39.56  ? 416 HOH D O   1 
HETATM 16880 O O   . HOH M 3 .   ? 46.654  -27.968 121.177 1.00 47.72  ? 417 HOH D O   1 
HETATM 16881 O O   . HOH M 3 .   ? 53.001  -36.405 134.856 1.00 45.24  ? 418 HOH D O   1 
HETATM 16882 O O   . HOH M 3 .   ? 57.930  -53.765 121.146 1.00 43.44  ? 419 HOH D O   1 
HETATM 16883 O O   . HOH M 3 .   ? 34.801  -22.794 114.975 1.00 52.01  ? 420 HOH D O   1 
HETATM 16884 O O   . HOH M 3 .   ? 31.324  -46.332 135.088 1.00 37.20  ? 421 HOH D O   1 
HETATM 16885 O O   . HOH M 3 .   ? 31.887  -44.336 136.935 1.00 42.85  ? 422 HOH D O   1 
HETATM 16886 O O   . HOH M 3 .   ? 47.353  -33.658 105.366 1.00 59.15  ? 423 HOH D O   1 
HETATM 16887 O O   . HOH M 3 .   ? 26.118  -56.112 139.927 1.00 46.98  ? 424 HOH D O   1 
HETATM 16888 O O   . HOH M 3 .   ? 67.790  -37.174 139.772 1.00 57.12  ? 425 HOH D O   1 
HETATM 16889 O O   . HOH M 3 .   ? 44.488  -60.311 125.542 1.00 37.91  ? 426 HOH D O   1 
HETATM 16890 O O   . HOH M 3 .   ? 50.937  -69.326 135.031 1.00 45.14  ? 427 HOH D O   1 
HETATM 16891 O O   . HOH N 3 .   ? 64.748  12.552  117.080 1.00 60.82  ? 401 HOH E O   1 
HETATM 16892 O O   . HOH N 3 .   ? 73.030  -5.556  104.555 1.00 43.11  ? 402 HOH E O   1 
HETATM 16893 O O   . HOH N 3 .   ? 70.045  -28.645 94.124  1.00 38.48  ? 403 HOH E O   1 
HETATM 16894 O O   . HOH N 3 .   ? 83.249  -11.331 97.107  1.00 44.87  ? 404 HOH E O   1 
HETATM 16895 O O   . HOH N 3 .   ? 73.145  -30.490 96.112  1.00 41.60  ? 405 HOH E O   1 
HETATM 16896 O O   . HOH N 3 .   ? 69.828  -2.082  107.619 1.00 41.33  ? 406 HOH E O   1 
HETATM 16897 O O   . HOH N 3 .   ? 63.106  -21.068 102.782 1.00 42.08  ? 407 HOH E O   1 
HETATM 16898 O O   . HOH N 3 .   ? 58.498  -21.666 102.492 1.00 42.21  ? 408 HOH E O   1 
HETATM 16899 O O   . HOH N 3 .   ? 50.666  -9.835  98.334  1.00 40.80  ? 409 HOH E O   1 
HETATM 16900 O O   . HOH N 3 .   ? 52.269  -15.369 87.677  1.00 43.90  ? 410 HOH E O   1 
HETATM 16901 O O   . HOH N 3 .   ? 74.686  16.776  120.486 1.00 73.80  ? 411 HOH E O   1 
HETATM 16902 O O   . HOH N 3 .   ? 57.780  8.100   92.572  1.00 38.51  ? 412 HOH E O   1 
HETATM 16903 O O   . HOH N 3 .   ? 61.531  -24.542 96.697  1.00 42.26  ? 413 HOH E O   1 
HETATM 16904 O O   . HOH N 3 .   ? 58.820  3.924   99.434  1.00 36.00  ? 414 HOH E O   1 
HETATM 16905 O O   . HOH N 3 .   ? 82.563  -9.472  101.439 1.00 49.36  ? 415 HOH E O   1 
HETATM 16906 O O   . HOH N 3 .   ? 73.248  4.393   130.091 1.00 74.37  ? 416 HOH E O   1 
HETATM 16907 O O   . HOH N 3 .   ? 83.206  -3.673  128.046 1.00 78.62  ? 417 HOH E O   1 
HETATM 16908 O O   . HOH N 3 .   ? 64.572  -19.404 112.521 1.00 48.62  ? 418 HOH E O   1 
HETATM 16909 O O   . HOH N 3 .   ? 55.549  3.509   87.222  1.00 41.70  ? 419 HOH E O   1 
HETATM 16910 O O   . HOH N 3 .   ? 81.082  -10.896 95.390  1.00 44.04  ? 420 HOH E O   1 
HETATM 16911 O O   . HOH N 3 .   ? 81.902  22.798  126.403 1.00 66.33  ? 421 HOH E O   1 
HETATM 16912 O O   . HOH N 3 .   ? 71.340  -19.457 89.382  1.00 47.50  ? 422 HOH E O   1 
HETATM 16913 O O   . HOH O 3 .   ? 2.044   -54.231 135.193 1.00 72.29  ? 401 HOH F O   1 
HETATM 16914 O O   . HOH O 3 .   ? 17.323  -14.456 143.775 1.00 53.13  ? 402 HOH F O   1 
HETATM 16915 O O   . HOH O 3 .   ? 11.874  -32.491 147.438 1.00 45.43  ? 403 HOH F O   1 
HETATM 16916 O O   . HOH O 3 .   ? 13.812  -11.544 135.964 1.00 53.32  ? 404 HOH F O   1 
HETATM 16917 O O   . HOH O 3 .   ? 8.620   -8.669  139.036 1.00 50.43  ? 405 HOH F O   1 
# 
