data_8REM
# 
_entry.id   8REM 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8REM         pdb_00008rem 10.2210/pdb8rem/pdb 
WWPDB D_1292135270 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8REM 
_pdbx_database_status.recvd_initial_deposition_date   2023-12-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ec.schulz@uke.de 
_pdbx_contact_author.name_first         Eike 
_pdbx_contact_author.name_last          Schulz 
_pdbx_contact_author.name_mi            C 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1685-8605 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bosman, R.'      1 0000-0002-9939-602X 
'Prester, A.'     2 0000-0003-2738-7682 
'von Soosten, L.' 3 0000-0001-7568-1013 
'Dibenedetto, S.' 4 ?                   
'Bartels, K.'     5 0000-0002-7980-1913 
'Sung, S.'        6 0000-0001-5820-4696 
'von Stetten, D.' 7 0000-0001-7906-9788 
'Mehrabi, P.'     8 0000-0003-3211-6959 
'Schulz, E.C.'    9 0000-0002-1685-8605 
# 
loop_
_citation.abstract 
_citation.abstract_id_CAS 
_citation.book_id_ISBN 
_citation.book_publisher 
_citation.book_publisher_city 
_citation.book_title 
_citation.coordinate_linkage 
_citation.country 
_citation.database_id_Medline 
_citation.details 
_citation.id 
_citation.journal_abbrev 
_citation.journal_id_ASTM 
_citation.journal_id_CSD 
_citation.journal_id_ISSN 
_citation.journal_full 
_citation.journal_issue 
_citation.journal_volume 
_citation.language 
_citation.page_first 
_citation.page_last 
_citation.title 
_citation.year 
_citation.database_id_CSD 
_citation.pdbx_database_id_DOI 
_citation.pdbx_database_id_PubMed 
_citation.pdbx_database_id_patent 
_citation.unpublished_flag 
? ? ? ? ? ? ? ?  ? ? primary 'To Be Published'                                ?      0353 ?         ? ? ?  ? ?   ?  
'Kapton-based HARE chips for fixed-target serial crystallography'             ?    ? ? ? ? ? 
? ? ? ? ? ? ? DK ? ? 1       'Acta Crystallogr., Sect. D: Biol. Crystallogr.' ABCRE6 0766 0907-4449 ? ? 68 ? 352 67 
'Towards automated crystallographic structure refinement with phenix.refine.' 2012 ? ? ? ? ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Bosman, R.'      1  0000-0002-9939-602X 
primary 'Prester, A.'     2  0000-0003-2738-7682 
primary 'von Soosten, L.' 3  0000-0001-7568-1013 
primary 'Dibenedetto, S.' 4  ?                   
primary 'Bartels, K.'     5  0000-0002-7980-1913 
primary 'Sung, S.'        6  0000-0001-5820-4696 
primary 'von Stetten, D.' 7  0000-0001-7906-9788 
primary 'Mehrabi, P.'     8  0000-0003-3211-6959 
primary 'Blatter, G.'     9  ?                   
primary 'Lu, G.'          10 ?                   
primary 'Bernhard, S.'    11 ?                   
primary 'Osbild, M.'      12 ?                   
primary 'Schulz, E.C.'    13 0000-0002-1685-8605 
1       'Afonine, P.V.'   14 ?                   
1       'Adams, P.D.'     15 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Beta-lactamase 27771.314 1   3.5.2.6 ? ? ? 
2 non-polymer syn 'SULFATE ION'  96.063    1   ?       ? ? ? 
3 water       nat water          18.015    165 ?       ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNP
IAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMA
QTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQ
QNAESRRDVLASAARIIAEGL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNP
IAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMA
QTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQ
QNAESRRDVLASAARIIAEGL
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SULFATE ION' SO4 
3 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   ALA n 
1 3   VAL n 
1 4   GLN n 
1 5   GLN n 
1 6   LYS n 
1 7   LEU n 
1 8   ALA n 
1 9   ALA n 
1 10  LEU n 
1 11  GLU n 
1 12  LYS n 
1 13  SER n 
1 14  SER n 
1 15  GLY n 
1 16  GLY n 
1 17  ARG n 
1 18  LEU n 
1 19  GLY n 
1 20  VAL n 
1 21  ALA n 
1 22  LEU n 
1 23  ILE n 
1 24  ASP n 
1 25  THR n 
1 26  ALA n 
1 27  ASP n 
1 28  ASN n 
1 29  THR n 
1 30  GLN n 
1 31  VAL n 
1 32  LEU n 
1 33  TYR n 
1 34  ARG n 
1 35  GLY n 
1 36  ASP n 
1 37  GLU n 
1 38  ARG n 
1 39  PHE n 
1 40  PRO n 
1 41  MET n 
1 42  CYS n 
1 43  SER n 
1 44  THR n 
1 45  SER n 
1 46  LYS n 
1 47  VAL n 
1 48  MET n 
1 49  ALA n 
1 50  ALA n 
1 51  ALA n 
1 52  ALA n 
1 53  VAL n 
1 54  LEU n 
1 55  LYS n 
1 56  GLN n 
1 57  SER n 
1 58  GLU n 
1 59  THR n 
1 60  GLN n 
1 61  LYS n 
1 62  GLN n 
1 63  LEU n 
1 64  LEU n 
1 65  ASN n 
1 66  GLN n 
1 67  PRO n 
1 68  VAL n 
1 69  GLU n 
1 70  ILE n 
1 71  LYS n 
1 72  PRO n 
1 73  ALA n 
1 74  ASP n 
1 75  LEU n 
1 76  VAL n 
1 77  ASN n 
1 78  TYR n 
1 79  ASN n 
1 80  PRO n 
1 81  ILE n 
1 82  ALA n 
1 83  GLU n 
1 84  LYS n 
1 85  HIS n 
1 86  VAL n 
1 87  ASN n 
1 88  GLY n 
1 89  THR n 
1 90  MET n 
1 91  THR n 
1 92  LEU n 
1 93  ALA n 
1 94  GLU n 
1 95  LEU n 
1 96  SER n 
1 97  ALA n 
1 98  ALA n 
1 99  ALA n 
1 100 LEU n 
1 101 GLN n 
1 102 TYR n 
1 103 SER n 
1 104 ASP n 
1 105 ASN n 
1 106 THR n 
1 107 ALA n 
1 108 MET n 
1 109 ASN n 
1 110 LYS n 
1 111 LEU n 
1 112 ILE n 
1 113 ALA n 
1 114 GLN n 
1 115 LEU n 
1 116 GLY n 
1 117 GLY n 
1 118 PRO n 
1 119 GLY n 
1 120 GLY n 
1 121 VAL n 
1 122 THR n 
1 123 ALA n 
1 124 PHE n 
1 125 ALA n 
1 126 ARG n 
1 127 ALA n 
1 128 ILE n 
1 129 GLY n 
1 130 ASP n 
1 131 GLU n 
1 132 THR n 
1 133 PHE n 
1 134 ARG n 
1 135 LEU n 
1 136 ASP n 
1 137 ARG n 
1 138 THR n 
1 139 GLU n 
1 140 PRO n 
1 141 THR n 
1 142 LEU n 
1 143 ASN n 
1 144 THR n 
1 145 ALA n 
1 146 ILE n 
1 147 PRO n 
1 148 GLY n 
1 149 ASP n 
1 150 PRO n 
1 151 ARG n 
1 152 ASP n 
1 153 THR n 
1 154 THR n 
1 155 THR n 
1 156 PRO n 
1 157 ARG n 
1 158 ALA n 
1 159 MET n 
1 160 ALA n 
1 161 GLN n 
1 162 THR n 
1 163 LEU n 
1 164 ARG n 
1 165 GLN n 
1 166 LEU n 
1 167 THR n 
1 168 LEU n 
1 169 GLY n 
1 170 HIS n 
1 171 ALA n 
1 172 LEU n 
1 173 GLY n 
1 174 GLU n 
1 175 THR n 
1 176 GLN n 
1 177 ARG n 
1 178 ALA n 
1 179 GLN n 
1 180 LEU n 
1 181 VAL n 
1 182 THR n 
1 183 TRP n 
1 184 LEU n 
1 185 LYS n 
1 186 GLY n 
1 187 ASN n 
1 188 THR n 
1 189 THR n 
1 190 GLY n 
1 191 ALA n 
1 192 ALA n 
1 193 SER n 
1 194 ILE n 
1 195 ARG n 
1 196 ALA n 
1 197 GLY n 
1 198 LEU n 
1 199 PRO n 
1 200 THR n 
1 201 SER n 
1 202 TRP n 
1 203 THR n 
1 204 VAL n 
1 205 GLY n 
1 206 ASP n 
1 207 LYS n 
1 208 THR n 
1 209 GLY n 
1 210 SER n 
1 211 GLY n 
1 212 ASP n 
1 213 TYR n 
1 214 GLY n 
1 215 THR n 
1 216 THR n 
1 217 ASN n 
1 218 ASP n 
1 219 ILE n 
1 220 ALA n 
1 221 VAL n 
1 222 ILE n 
1 223 TRP n 
1 224 PRO n 
1 225 GLN n 
1 226 GLY n 
1 227 ARG n 
1 228 ALA n 
1 229 PRO n 
1 230 LEU n 
1 231 VAL n 
1 232 LEU n 
1 233 VAL n 
1 234 THR n 
1 235 TYR n 
1 236 PHE n 
1 237 THR n 
1 238 GLN n 
1 239 PRO n 
1 240 GLN n 
1 241 GLN n 
1 242 ASN n 
1 243 ALA n 
1 244 GLU n 
1 245 SER n 
1 246 ARG n 
1 247 ARG n 
1 248 ASP n 
1 249 VAL n 
1 250 LEU n 
1 251 ALA n 
1 252 SER n 
1 253 ALA n 
1 254 ALA n 
1 255 ARG n 
1 256 ILE n 
1 257 ILE n 
1 258 ALA n 
1 259 GLU n 
1 260 GLY n 
1 261 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   261 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ctx-m-14 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Klebsiella pneumoniae' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     573 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   28  28  SER SER A . n 
A 1 2   ALA 2   29  29  ALA ALA A . n 
A 1 3   VAL 3   30  30  VAL VAL A . n 
A 1 4   GLN 4   31  31  GLN GLN A . n 
A 1 5   GLN 5   32  32  GLN GLN A . n 
A 1 6   LYS 6   33  33  LYS LYS A . n 
A 1 7   LEU 7   34  34  LEU LEU A . n 
A 1 8   ALA 8   35  35  ALA ALA A . n 
A 1 9   ALA 9   36  36  ALA ALA A . n 
A 1 10  LEU 10  37  37  LEU LEU A . n 
A 1 11  GLU 11  38  38  GLU GLU A . n 
A 1 12  LYS 12  39  39  LYS LYS A . n 
A 1 13  SER 13  40  40  SER SER A . n 
A 1 14  SER 14  41  41  SER SER A . n 
A 1 15  GLY 15  42  42  GLY GLY A . n 
A 1 16  GLY 16  43  43  GLY GLY A . n 
A 1 17  ARG 17  44  44  ARG ARG A . n 
A 1 18  LEU 18  45  45  LEU LEU A . n 
A 1 19  GLY 19  46  46  GLY GLY A . n 
A 1 20  VAL 20  47  47  VAL VAL A . n 
A 1 21  ALA 21  48  48  ALA ALA A . n 
A 1 22  LEU 22  49  49  LEU LEU A . n 
A 1 23  ILE 23  50  50  ILE ILE A . n 
A 1 24  ASP 24  51  51  ASP ASP A . n 
A 1 25  THR 25  52  52  THR THR A . n 
A 1 26  ALA 26  53  53  ALA ALA A . n 
A 1 27  ASP 27  54  54  ASP ASP A . n 
A 1 28  ASN 28  55  55  ASN ASN A . n 
A 1 29  THR 29  56  56  THR THR A . n 
A 1 30  GLN 30  57  57  GLN GLN A . n 
A 1 31  VAL 31  58  58  VAL VAL A . n 
A 1 32  LEU 32  59  59  LEU LEU A . n 
A 1 33  TYR 33  60  60  TYR TYR A . n 
A 1 34  ARG 34  61  61  ARG ARG A . n 
A 1 35  GLY 35  62  62  GLY GLY A . n 
A 1 36  ASP 36  63  63  ASP ASP A . n 
A 1 37  GLU 37  64  64  GLU GLU A . n 
A 1 38  ARG 38  65  65  ARG ARG A . n 
A 1 39  PHE 39  66  66  PHE PHE A . n 
A 1 40  PRO 40  67  67  PRO PRO A . n 
A 1 41  MET 41  68  68  MET MET A . n 
A 1 42  CYS 42  69  69  CYS CYS A . n 
A 1 43  SER 43  70  70  SER SER A . n 
A 1 44  THR 44  71  71  THR THR A . n 
A 1 45  SER 45  72  72  SER SER A . n 
A 1 46  LYS 46  73  73  LYS LYS A . n 
A 1 47  VAL 47  74  74  VAL VAL A . n 
A 1 48  MET 48  75  75  MET MET A . n 
A 1 49  ALA 49  76  76  ALA ALA A . n 
A 1 50  ALA 50  77  77  ALA ALA A . n 
A 1 51  ALA 51  78  78  ALA ALA A . n 
A 1 52  ALA 52  79  79  ALA ALA A . n 
A 1 53  VAL 53  80  80  VAL VAL A . n 
A 1 54  LEU 54  81  81  LEU LEU A . n 
A 1 55  LYS 55  82  82  LYS LYS A . n 
A 1 56  GLN 56  83  83  GLN GLN A . n 
A 1 57  SER 57  84  84  SER SER A . n 
A 1 58  GLU 58  85  85  GLU GLU A . n 
A 1 59  THR 59  86  86  THR THR A . n 
A 1 60  GLN 60  87  87  GLN GLN A . n 
A 1 61  LYS 61  88  88  LYS LYS A . n 
A 1 62  GLN 62  89  89  GLN GLN A . n 
A 1 63  LEU 63  90  90  LEU LEU A . n 
A 1 64  LEU 64  91  91  LEU LEU A . n 
A 1 65  ASN 65  92  92  ASN ASN A . n 
A 1 66  GLN 66  93  93  GLN GLN A . n 
A 1 67  PRO 67  94  94  PRO PRO A . n 
A 1 68  VAL 68  95  95  VAL VAL A . n 
A 1 69  GLU 69  96  96  GLU GLU A . n 
A 1 70  ILE 70  97  97  ILE ILE A . n 
A 1 71  LYS 71  98  98  LYS LYS A . n 
A 1 72  PRO 72  99  99  PRO PRO A . n 
A 1 73  ALA 73  100 100 ALA ALA A . n 
A 1 74  ASP 74  101 101 ASP ASP A . n 
A 1 75  LEU 75  102 102 LEU LEU A . n 
A 1 76  VAL 76  103 103 VAL VAL A . n 
A 1 77  ASN 77  104 104 ASN ASN A . n 
A 1 78  TYR 78  105 105 TYR TYR A . n 
A 1 79  ASN 79  106 106 ASN ASN A . n 
A 1 80  PRO 80  107 107 PRO PRO A . n 
A 1 81  ILE 81  108 108 ILE ILE A . n 
A 1 82  ALA 82  109 109 ALA ALA A . n 
A 1 83  GLU 83  110 110 GLU GLU A . n 
A 1 84  LYS 84  111 111 LYS LYS A . n 
A 1 85  HIS 85  112 112 HIS HIS A . n 
A 1 86  VAL 86  113 113 VAL VAL A . n 
A 1 87  ASN 87  114 114 ASN ASN A . n 
A 1 88  GLY 88  115 115 GLY GLY A . n 
A 1 89  THR 89  116 116 THR THR A . n 
A 1 90  MET 90  117 117 MET MET A . n 
A 1 91  THR 91  118 118 THR THR A . n 
A 1 92  LEU 92  119 119 LEU LEU A . n 
A 1 93  ALA 93  120 120 ALA ALA A . n 
A 1 94  GLU 94  121 121 GLU GLU A . n 
A 1 95  LEU 95  122 122 LEU LEU A . n 
A 1 96  SER 96  123 123 SER SER A . n 
A 1 97  ALA 97  124 124 ALA ALA A . n 
A 1 98  ALA 98  125 125 ALA ALA A . n 
A 1 99  ALA 99  126 126 ALA ALA A . n 
A 1 100 LEU 100 127 127 LEU LEU A . n 
A 1 101 GLN 101 128 128 GLN GLN A . n 
A 1 102 TYR 102 129 129 TYR TYR A . n 
A 1 103 SER 103 130 130 SER SER A . n 
A 1 104 ASP 104 131 131 ASP ASP A . n 
A 1 105 ASN 105 132 132 ASN ASN A . n 
A 1 106 THR 106 133 133 THR THR A . n 
A 1 107 ALA 107 134 134 ALA ALA A . n 
A 1 108 MET 108 135 135 MET MET A . n 
A 1 109 ASN 109 136 136 ASN ASN A . n 
A 1 110 LYS 110 137 137 LYS LYS A . n 
A 1 111 LEU 111 138 138 LEU LEU A . n 
A 1 112 ILE 112 139 139 ILE ILE A . n 
A 1 113 ALA 113 140 140 ALA ALA A . n 
A 1 114 GLN 114 141 141 GLN GLN A . n 
A 1 115 LEU 115 142 142 LEU LEU A . n 
A 1 116 GLY 116 143 143 GLY GLY A . n 
A 1 117 GLY 117 144 144 GLY GLY A . n 
A 1 118 PRO 118 145 145 PRO PRO A . n 
A 1 119 GLY 119 146 146 GLY GLY A . n 
A 1 120 GLY 120 147 147 GLY GLY A . n 
A 1 121 VAL 121 148 148 VAL VAL A . n 
A 1 122 THR 122 149 149 THR THR A . n 
A 1 123 ALA 123 150 150 ALA ALA A . n 
A 1 124 PHE 124 151 151 PHE PHE A . n 
A 1 125 ALA 125 152 152 ALA ALA A . n 
A 1 126 ARG 126 153 153 ARG ARG A . n 
A 1 127 ALA 127 154 154 ALA ALA A . n 
A 1 128 ILE 128 155 155 ILE ILE A . n 
A 1 129 GLY 129 156 156 GLY GLY A . n 
A 1 130 ASP 130 157 157 ASP ASP A . n 
A 1 131 GLU 131 158 158 GLU GLU A . n 
A 1 132 THR 132 159 159 THR THR A . n 
A 1 133 PHE 133 160 160 PHE PHE A . n 
A 1 134 ARG 134 161 161 ARG ARG A . n 
A 1 135 LEU 135 162 162 LEU LEU A . n 
A 1 136 ASP 136 163 163 ASP ASP A . n 
A 1 137 ARG 137 164 164 ARG ARG A . n 
A 1 138 THR 138 165 165 THR THR A . n 
A 1 139 GLU 139 166 166 GLU GLU A . n 
A 1 140 PRO 140 167 167 PRO PRO A . n 
A 1 141 THR 141 168 168 THR THR A . n 
A 1 142 LEU 142 169 169 LEU LEU A . n 
A 1 143 ASN 143 170 170 ASN ASN A . n 
A 1 144 THR 144 171 171 THR THR A . n 
A 1 145 ALA 145 172 172 ALA ALA A . n 
A 1 146 ILE 146 173 173 ILE ILE A . n 
A 1 147 PRO 147 174 174 PRO PRO A . n 
A 1 148 GLY 148 175 175 GLY GLY A . n 
A 1 149 ASP 149 176 176 ASP ASP A . n 
A 1 150 PRO 150 177 177 PRO PRO A . n 
A 1 151 ARG 151 178 178 ARG ARG A . n 
A 1 152 ASP 152 179 179 ASP ASP A . n 
A 1 153 THR 153 180 180 THR THR A . n 
A 1 154 THR 154 181 181 THR THR A . n 
A 1 155 THR 155 182 182 THR THR A . n 
A 1 156 PRO 156 183 183 PRO PRO A . n 
A 1 157 ARG 157 184 184 ARG ARG A . n 
A 1 158 ALA 158 185 185 ALA ALA A . n 
A 1 159 MET 159 186 186 MET MET A . n 
A 1 160 ALA 160 187 187 ALA ALA A . n 
A 1 161 GLN 161 188 188 GLN GLN A . n 
A 1 162 THR 162 189 189 THR THR A . n 
A 1 163 LEU 163 190 190 LEU LEU A . n 
A 1 164 ARG 164 191 191 ARG ARG A . n 
A 1 165 GLN 165 192 192 GLN GLN A . n 
A 1 166 LEU 166 193 193 LEU LEU A . n 
A 1 167 THR 167 194 194 THR THR A . n 
A 1 168 LEU 168 195 195 LEU LEU A . n 
A 1 169 GLY 169 196 196 GLY GLY A . n 
A 1 170 HIS 170 197 197 HIS HIS A . n 
A 1 171 ALA 171 198 198 ALA ALA A . n 
A 1 172 LEU 172 199 199 LEU LEU A . n 
A 1 173 GLY 173 200 200 GLY GLY A . n 
A 1 174 GLU 174 201 201 GLU GLU A . n 
A 1 175 THR 175 202 202 THR THR A . n 
A 1 176 GLN 176 203 203 GLN GLN A . n 
A 1 177 ARG 177 204 204 ARG ARG A . n 
A 1 178 ALA 178 205 205 ALA ALA A . n 
A 1 179 GLN 179 206 206 GLN GLN A . n 
A 1 180 LEU 180 207 207 LEU LEU A . n 
A 1 181 VAL 181 208 208 VAL VAL A . n 
A 1 182 THR 182 209 209 THR THR A . n 
A 1 183 TRP 183 210 210 TRP TRP A . n 
A 1 184 LEU 184 211 211 LEU LEU A . n 
A 1 185 LYS 185 212 212 LYS LYS A . n 
A 1 186 GLY 186 213 213 GLY GLY A . n 
A 1 187 ASN 187 214 214 ASN ASN A . n 
A 1 188 THR 188 215 215 THR THR A . n 
A 1 189 THR 189 216 216 THR THR A . n 
A 1 190 GLY 190 217 217 GLY GLY A . n 
A 1 191 ALA 191 218 218 ALA ALA A . n 
A 1 192 ALA 192 219 219 ALA ALA A . n 
A 1 193 SER 193 220 220 SER SER A . n 
A 1 194 ILE 194 221 221 ILE ILE A . n 
A 1 195 ARG 195 222 222 ARG ARG A . n 
A 1 196 ALA 196 223 223 ALA ALA A . n 
A 1 197 GLY 197 224 224 GLY GLY A . n 
A 1 198 LEU 198 225 225 LEU LEU A . n 
A 1 199 PRO 199 226 226 PRO PRO A . n 
A 1 200 THR 200 227 227 THR THR A . n 
A 1 201 SER 201 228 228 SER SER A . n 
A 1 202 TRP 202 229 229 TRP TRP A . n 
A 1 203 THR 203 230 230 THR THR A . n 
A 1 204 VAL 204 231 231 VAL VAL A . n 
A 1 205 GLY 205 232 232 GLY GLY A . n 
A 1 206 ASP 206 233 233 ASP ASP A . n 
A 1 207 LYS 207 234 234 LYS LYS A . n 
A 1 208 THR 208 235 235 THR THR A . n 
A 1 209 GLY 209 236 236 GLY GLY A . n 
A 1 210 SER 210 237 237 SER SER A . n 
A 1 211 GLY 211 238 238 GLY GLY A . n 
A 1 212 ASP 212 239 239 ASP ASP A . n 
A 1 213 TYR 213 240 240 TYR TYR A . n 
A 1 214 GLY 214 241 241 GLY GLY A . n 
A 1 215 THR 215 242 242 THR THR A . n 
A 1 216 THR 216 243 243 THR THR A . n 
A 1 217 ASN 217 244 244 ASN ASN A . n 
A 1 218 ASP 218 245 245 ASP ASP A . n 
A 1 219 ILE 219 246 246 ILE ILE A . n 
A 1 220 ALA 220 247 247 ALA ALA A . n 
A 1 221 VAL 221 248 248 VAL VAL A . n 
A 1 222 ILE 222 249 249 ILE ILE A . n 
A 1 223 TRP 223 250 250 TRP TRP A . n 
A 1 224 PRO 224 251 251 PRO PRO A . n 
A 1 225 GLN 225 252 252 GLN GLN A . n 
A 1 226 GLY 226 253 253 GLY GLY A . n 
A 1 227 ARG 227 254 254 ARG ARG A . n 
A 1 228 ALA 228 255 255 ALA ALA A . n 
A 1 229 PRO 229 256 256 PRO PRO A . n 
A 1 230 LEU 230 257 257 LEU LEU A . n 
A 1 231 VAL 231 258 258 VAL VAL A . n 
A 1 232 LEU 232 259 259 LEU LEU A . n 
A 1 233 VAL 233 260 260 VAL VAL A . n 
A 1 234 THR 234 261 261 THR THR A . n 
A 1 235 TYR 235 262 262 TYR TYR A . n 
A 1 236 PHE 236 263 263 PHE PHE A . n 
A 1 237 THR 237 264 264 THR THR A . n 
A 1 238 GLN 238 265 265 GLN GLN A . n 
A 1 239 PRO 239 266 266 PRO PRO A . n 
A 1 240 GLN 240 267 267 GLN GLN A . n 
A 1 241 GLN 241 268 268 GLN GLN A . n 
A 1 242 ASN 242 269 269 ASN ASN A . n 
A 1 243 ALA 243 270 270 ALA ALA A . n 
A 1 244 GLU 244 271 271 GLU GLU A . n 
A 1 245 SER 245 272 272 SER SER A . n 
A 1 246 ARG 246 273 273 ARG ARG A . n 
A 1 247 ARG 247 274 274 ARG ARG A . n 
A 1 248 ASP 248 275 275 ASP ASP A . n 
A 1 249 VAL 249 276 276 VAL VAL A . n 
A 1 250 LEU 250 277 277 LEU LEU A . n 
A 1 251 ALA 251 278 278 ALA ALA A . n 
A 1 252 SER 252 279 279 SER SER A . n 
A 1 253 ALA 253 280 280 ALA ALA A . n 
A 1 254 ALA 254 281 281 ALA ALA A . n 
A 1 255 ARG 255 282 282 ARG ARG A . n 
A 1 256 ILE 256 283 283 ILE ILE A . n 
A 1 257 ILE 257 284 284 ILE ILE A . n 
A 1 258 ALA 258 285 285 ALA ALA A . n 
A 1 259 GLU 259 286 286 GLU GLU A . n 
A 1 260 GLY 260 287 287 GLY GLY A . n 
A 1 261 LEU 261 288 ?   ?   ?   A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 SO4 1   301 1   SO4 SO4 A . 
C 3 HOH 1   401 50  HOH HOH A . 
C 3 HOH 2   402 189 HOH HOH A . 
C 3 HOH 3   403 174 HOH HOH A . 
C 3 HOH 4   404 109 HOH HOH A . 
C 3 HOH 5   405 63  HOH HOH A . 
C 3 HOH 6   406 62  HOH HOH A . 
C 3 HOH 7   407 72  HOH HOH A . 
C 3 HOH 8   408 150 HOH HOH A . 
C 3 HOH 9   409 37  HOH HOH A . 
C 3 HOH 10  410 107 HOH HOH A . 
C 3 HOH 11  411 34  HOH HOH A . 
C 3 HOH 12  412 51  HOH HOH A . 
C 3 HOH 13  413 129 HOH HOH A . 
C 3 HOH 14  414 13  HOH HOH A . 
C 3 HOH 15  415 176 HOH HOH A . 
C 3 HOH 16  416 171 HOH HOH A . 
C 3 HOH 17  417 5   HOH HOH A . 
C 3 HOH 18  418 28  HOH HOH A . 
C 3 HOH 19  419 71  HOH HOH A . 
C 3 HOH 20  420 49  HOH HOH A . 
C 3 HOH 21  421 48  HOH HOH A . 
C 3 HOH 22  422 88  HOH HOH A . 
C 3 HOH 23  423 76  HOH HOH A . 
C 3 HOH 24  424 65  HOH HOH A . 
C 3 HOH 25  425 113 HOH HOH A . 
C 3 HOH 26  426 154 HOH HOH A . 
C 3 HOH 27  427 25  HOH HOH A . 
C 3 HOH 28  428 75  HOH HOH A . 
C 3 HOH 29  429 167 HOH HOH A . 
C 3 HOH 30  430 24  HOH HOH A . 
C 3 HOH 31  431 33  HOH HOH A . 
C 3 HOH 32  432 8   HOH HOH A . 
C 3 HOH 33  433 32  HOH HOH A . 
C 3 HOH 34  434 10  HOH HOH A . 
C 3 HOH 35  435 117 HOH HOH A . 
C 3 HOH 36  436 52  HOH HOH A . 
C 3 HOH 37  437 16  HOH HOH A . 
C 3 HOH 38  438 7   HOH HOH A . 
C 3 HOH 39  439 36  HOH HOH A . 
C 3 HOH 40  440 56  HOH HOH A . 
C 3 HOH 41  441 85  HOH HOH A . 
C 3 HOH 42  442 121 HOH HOH A . 
C 3 HOH 43  443 2   HOH HOH A . 
C 3 HOH 44  444 9   HOH HOH A . 
C 3 HOH 45  445 61  HOH HOH A . 
C 3 HOH 46  446 3   HOH HOH A . 
C 3 HOH 47  447 4   HOH HOH A . 
C 3 HOH 48  448 169 HOH HOH A . 
C 3 HOH 49  449 17  HOH HOH A . 
C 3 HOH 50  450 59  HOH HOH A . 
C 3 HOH 51  451 12  HOH HOH A . 
C 3 HOH 52  452 183 HOH HOH A . 
C 3 HOH 53  453 1   HOH HOH A . 
C 3 HOH 54  454 31  HOH HOH A . 
C 3 HOH 55  455 6   HOH HOH A . 
C 3 HOH 56  456 186 HOH HOH A . 
C 3 HOH 57  457 23  HOH HOH A . 
C 3 HOH 58  458 105 HOH HOH A . 
C 3 HOH 59  459 110 HOH HOH A . 
C 3 HOH 60  460 15  HOH HOH A . 
C 3 HOH 61  461 123 HOH HOH A . 
C 3 HOH 62  462 22  HOH HOH A . 
C 3 HOH 63  463 29  HOH HOH A . 
C 3 HOH 64  464 89  HOH HOH A . 
C 3 HOH 65  465 35  HOH HOH A . 
C 3 HOH 66  466 91  HOH HOH A . 
C 3 HOH 67  467 58  HOH HOH A . 
C 3 HOH 68  468 120 HOH HOH A . 
C 3 HOH 69  469 39  HOH HOH A . 
C 3 HOH 70  470 122 HOH HOH A . 
C 3 HOH 71  471 73  HOH HOH A . 
C 3 HOH 72  472 67  HOH HOH A . 
C 3 HOH 73  473 47  HOH HOH A . 
C 3 HOH 74  474 168 HOH HOH A . 
C 3 HOH 75  475 38  HOH HOH A . 
C 3 HOH 76  476 184 HOH HOH A . 
C 3 HOH 77  477 41  HOH HOH A . 
C 3 HOH 78  478 14  HOH HOH A . 
C 3 HOH 79  479 80  HOH HOH A . 
C 3 HOH 80  480 40  HOH HOH A . 
C 3 HOH 81  481 57  HOH HOH A . 
C 3 HOH 82  482 163 HOH HOH A . 
C 3 HOH 83  483 141 HOH HOH A . 
C 3 HOH 84  484 137 HOH HOH A . 
C 3 HOH 85  485 190 HOH HOH A . 
C 3 HOH 86  486 108 HOH HOH A . 
C 3 HOH 87  487 68  HOH HOH A . 
C 3 HOH 88  488 173 HOH HOH A . 
C 3 HOH 89  489 20  HOH HOH A . 
C 3 HOH 90  490 60  HOH HOH A . 
C 3 HOH 91  491 18  HOH HOH A . 
C 3 HOH 92  492 53  HOH HOH A . 
C 3 HOH 93  493 114 HOH HOH A . 
C 3 HOH 94  494 11  HOH HOH A . 
C 3 HOH 95  495 26  HOH HOH A . 
C 3 HOH 96  496 182 HOH HOH A . 
C 3 HOH 97  497 30  HOH HOH A . 
C 3 HOH 98  498 187 HOH HOH A . 
C 3 HOH 99  499 55  HOH HOH A . 
C 3 HOH 100 500 96  HOH HOH A . 
C 3 HOH 101 501 86  HOH HOH A . 
C 3 HOH 102 502 133 HOH HOH A . 
C 3 HOH 103 503 19  HOH HOH A . 
C 3 HOH 104 504 125 HOH HOH A . 
C 3 HOH 105 505 135 HOH HOH A . 
C 3 HOH 106 506 102 HOH HOH A . 
C 3 HOH 107 507 116 HOH HOH A . 
C 3 HOH 108 508 140 HOH HOH A . 
C 3 HOH 109 509 93  HOH HOH A . 
C 3 HOH 110 510 103 HOH HOH A . 
C 3 HOH 111 511 97  HOH HOH A . 
C 3 HOH 112 512 21  HOH HOH A . 
C 3 HOH 113 513 43  HOH HOH A . 
C 3 HOH 114 514 181 HOH HOH A . 
C 3 HOH 115 515 77  HOH HOH A . 
C 3 HOH 116 516 27  HOH HOH A . 
C 3 HOH 117 517 74  HOH HOH A . 
C 3 HOH 118 518 45  HOH HOH A . 
C 3 HOH 119 519 66  HOH HOH A . 
C 3 HOH 120 520 78  HOH HOH A . 
C 3 HOH 121 521 146 HOH HOH A . 
C 3 HOH 122 522 64  HOH HOH A . 
C 3 HOH 123 523 145 HOH HOH A . 
C 3 HOH 124 524 188 HOH HOH A . 
C 3 HOH 125 525 127 HOH HOH A . 
C 3 HOH 126 526 130 HOH HOH A . 
C 3 HOH 127 527 44  HOH HOH A . 
C 3 HOH 128 528 46  HOH HOH A . 
C 3 HOH 129 529 92  HOH HOH A . 
C 3 HOH 130 530 115 HOH HOH A . 
C 3 HOH 131 531 90  HOH HOH A . 
C 3 HOH 132 532 162 HOH HOH A . 
C 3 HOH 133 533 185 HOH HOH A . 
C 3 HOH 134 534 139 HOH HOH A . 
C 3 HOH 135 535 148 HOH HOH A . 
C 3 HOH 136 536 136 HOH HOH A . 
C 3 HOH 137 537 126 HOH HOH A . 
C 3 HOH 138 538 79  HOH HOH A . 
C 3 HOH 139 539 156 HOH HOH A . 
C 3 HOH 140 540 164 HOH HOH A . 
C 3 HOH 141 541 54  HOH HOH A . 
C 3 HOH 142 542 81  HOH HOH A . 
C 3 HOH 143 543 95  HOH HOH A . 
C 3 HOH 144 544 70  HOH HOH A . 
C 3 HOH 145 545 128 HOH HOH A . 
C 3 HOH 146 546 87  HOH HOH A . 
C 3 HOH 147 547 132 HOH HOH A . 
C 3 HOH 148 548 104 HOH HOH A . 
C 3 HOH 149 549 149 HOH HOH A . 
C 3 HOH 150 550 99  HOH HOH A . 
C 3 HOH 151 551 165 HOH HOH A . 
C 3 HOH 152 552 98  HOH HOH A . 
C 3 HOH 153 553 82  HOH HOH A . 
C 3 HOH 154 554 106 HOH HOH A . 
C 3 HOH 155 555 83  HOH HOH A . 
C 3 HOH 156 556 111 HOH HOH A . 
C 3 HOH 157 557 112 HOH HOH A . 
C 3 HOH 158 558 152 HOH HOH A . 
C 3 HOH 159 559 101 HOH HOH A . 
C 3 HOH 160 560 42  HOH HOH A . 
C 3 HOH 161 561 138 HOH HOH A . 
C 3 HOH 162 562 180 HOH HOH A . 
C 3 HOH 163 563 100 HOH HOH A . 
C 3 HOH 164 564 177 HOH HOH A . 
C 3 HOH 165 565 124 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? 0.10.2      2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? 0.10.2      3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? 2.8.3       4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8REM 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     42.150 
_cell.length_a_esd                 ? 
_cell.length_b                     42.150 
_cell.length_b_esd                 ? 
_cell.length_c                     234.200 
_cell.length_c_esd                 ? 
_cell.volume                       360340.171 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8REM 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8REM 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.17 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          43.35 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;CTX-M-14 solution (22 mg/ml) was mixed with 
45% precipitant solution (40% PEG8000, 200mM lithium sulfate, 100mM 
sodium acetate, pH 4.5) and with 5% undiluted seed stock in batch
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     293 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   Y 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 4M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-04-29 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.976 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.976 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   'P14 (MX2)' 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, EMBL c/o DESY' 
# 
_reflns.B_iso_Wilson_estimate                          20.71 
_reflns.entry_id                                       8REM 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.63 
_reflns.d_resolution_low                               78.07 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     31622 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.99 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                337.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.52 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.983 
_reflns.pdbx_CC_star                                   0.996 
_reflns.pdbx_R_split                                   0.0979 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.63 
_reflns_shell.d_res_low                                     1.68 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.40 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2673 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.686 
_reflns_shell.pdbx_CC_star                                  0.902 
_reflns_shell.pdbx_R_split                                  0.727 
_reflns_shell.percent_possible_all                          99.93 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               29.41 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8REM 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.63 
_refine.ls_d_res_low                             78.07 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     31412 
_refine.ls_number_reflns_R_free                  1552 
_refine.ls_number_reflns_R_work                  29860 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.18 
_refine.ls_percent_reflns_R_free                 4.94 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1568 
_refine.ls_R_factor_R_free                       0.1825 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1555 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 18.7888 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1576 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.63 
_refine_hist.d_res_low                        78.07 
_refine_hist.number_atoms_solvent             165 
_refine_hist.number_atoms_total               2111 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1941 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         5 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0106  ? 2142 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0792  ? 2941 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0647  ? 343  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0099  ? 396  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 13.6615 ? 808  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.63 1.68  . . 96  2499 92.22  . . . . 0.2848 . . . . . . . . . . . 0.3422 
'X-RAY DIFFRACTION' 1.68 1.74  . . 118 2689 99.54  . . . . 0.2236 . . . . . . . . . . . 0.2951 
'X-RAY DIFFRACTION' 1.74 1.81  . . 166 2605 99.71  . . . . 0.2167 . . . . . . . . . . . 0.2520 
'X-RAY DIFFRACTION' 1.81 1.89  . . 152 2683 99.75  . . . . 0.2009 . . . . . . . . . . . 0.2484 
'X-RAY DIFFRACTION' 1.89 1.99  . . 135 2721 99.93  . . . . 0.1552 . . . . . . . . . . . 0.1820 
'X-RAY DIFFRACTION' 1.99 2.12  . . 165 2670 99.93  . . . . 0.1479 . . . . . . . . . . . 0.1602 
'X-RAY DIFFRACTION' 2.12 2.28  . . 143 2707 99.89  . . . . 0.1480 . . . . . . . . . . . 0.1631 
'X-RAY DIFFRACTION' 2.28 2.51  . . 147 2725 99.90  . . . . 0.1595 . . . . . . . . . . . 0.1695 
'X-RAY DIFFRACTION' 2.51 2.87  . . 107 2780 99.93  . . . . 0.1594 . . . . . . . . . . . 0.1886 
'X-RAY DIFFRACTION' 2.87 3.62  . . 160 2795 100.00 . . . . 0.1503 . . . . . . . . . . . 0.1938 
'X-RAY DIFFRACTION' 3.62 78.07 . . 163 2986 99.94  . . . . 0.1289 . . . . . . . . . . . 0.1537 
# 
_struct.entry_id                     8REM 
_struct.title                        'CTX-M-14 measured via serial crystallography from a kapton HARE-chip (50 micron)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8REM 
_struct_keywords.text            'Lysozyme, Hydrolase, enzyme, muramidase' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    D2D9A0_KLEPN 
_struct_ref.pdbx_db_accession          D2D9A0 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;SAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNP
IAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMA
QTLRQLTLGHALGETQRAQLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQ
QNAESRRDVLASAARIIAEGL
;
_struct_ref.pdbx_align_begin           23 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8REM 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 261 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             D2D9A0 
_struct_ref_seq.db_align_beg                  23 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  283 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       28 
_struct_ref_seq.pdbx_auth_seq_align_end       288 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 220   ? 
1 MORE         -17   ? 
1 'SSA (A^2)'  10680 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 1   ? GLY A 15  ? SER A 28  GLY A 42  1 ? 15 
HELX_P HELX_P2  AA2 CYS A 42  ? THR A 44  ? CYS A 69  THR A 71  5 ? 3  
HELX_P HELX_P3  AA3 SER A 45  ? SER A 57  ? SER A 72  SER A 84  1 ? 13 
HELX_P HELX_P4  AA4 GLN A 62  ? ASN A 65  ? GLN A 89  ASN A 92  5 ? 4  
HELX_P HELX_P5  AA5 LYS A 71  ? LEU A 75  ? LYS A 98  LEU A 102 5 ? 5  
HELX_P HELX_P6  AA6 ILE A 81  ? VAL A 86  ? ILE A 108 VAL A 113 5 ? 6  
HELX_P HELX_P7  AA7 LEU A 92  ? SER A 103 ? LEU A 119 SER A 130 1 ? 12 
HELX_P HELX_P8  AA8 ASP A 104 ? LEU A 115 ? ASP A 131 LEU A 142 1 ? 12 
HELX_P HELX_P9  AA9 GLY A 117 ? ILE A 128 ? GLY A 144 ILE A 155 1 ? 12 
HELX_P HELX_P10 AB1 PRO A 140 ? THR A 144 ? PRO A 167 THR A 171 5 ? 5  
HELX_P HELX_P11 AB2 THR A 155 ? LEU A 168 ? THR A 182 LEU A 195 1 ? 14 
HELX_P HELX_P12 AB3 GLY A 173 ? GLY A 186 ? GLY A 200 GLY A 213 1 ? 14 
HELX_P HELX_P13 AB4 SER A 193 ? LEU A 198 ? SER A 220 LEU A 225 5 ? 6  
HELX_P HELX_P14 AB5 ARG A 246 ? GLY A 260 ? ARG A 273 GLY A 287 1 ? 15 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLU 
_struct_mon_prot_cis.label_seq_id           139 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLU 
_struct_mon_prot_cis.auth_seq_id            166 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    140 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     167 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       4.69 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 29  ? TYR A 33  ? THR A 56  TYR A 60  
AA1 2 ARG A 17  ? ASP A 24  ? ARG A 44  ASP A 51  
AA1 3 LEU A 230 ? THR A 237 ? LEU A 257 THR A 264 
AA1 4 THR A 215 ? TRP A 223 ? THR A 242 TRP A 250 
AA1 5 THR A 203 ? GLY A 211 ? THR A 230 GLY A 238 
AA2 1 PHE A 39  ? PRO A 40  ? PHE A 66  PRO A 67  
AA2 2 THR A 153 ? THR A 154 ? THR A 180 THR A 181 
AA3 1 PRO A 67  ? ILE A 70  ? PRO A 94  ILE A 97  
AA3 2 GLY A 88  ? THR A 91  ? GLY A 115 THR A 118 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O VAL A 31  ? O VAL A 58  N LEU A 22  ? N LEU A 49  
AA1 2 3 N GLY A 19  ? N GLY A 46  O TYR A 235 ? O TYR A 262 
AA1 3 4 O LEU A 230 ? O LEU A 257 N ILE A 222 ? N ILE A 249 
AA1 4 5 O ASN A 217 ? O ASN A 244 N GLY A 209 ? N GLY A 236 
AA2 1 2 N PHE A 39  ? N PHE A 66  O THR A 154 ? O THR A 181 
AA3 1 2 N ILE A 70  ? N ILE A 97  O GLY A 88  ? O GLY A 115 
# 
_pdbx_entry_details.entry_id                   8REM 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 CYS A 69  ? ? 46.04   -138.94 
2 1 VAL A 103 ? ? -115.03 -136.16 
3 1 SER A 220 ? ? -106.08 -127.67 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 -y+1/2,x+1/2,z+3/4  
3 y+1/2,-x+1/2,z+1/4  
4 x+1/2,-y+1/2,-z+1/4 
5 -x+1/2,y+1/2,-z+3/4 
6 -x,-y,z+1/2         
7 y,x,-z              
8 -y,-x,-z+1/2        
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined -12.6099216339 -11.1279191711  7.17458281373 0.160683761799 ? -0.00168218352874 ? -0.0341075144228 
? 0.300220355079  ? 0.0092481171861   ? 0.156355279433 ? 4.17341768864  ? -2.34284235067  ? -1.42334064021 ? 4.31646780937 ? 
0.825102219362 ? 2.33257533023 ? -0.143402996813  ? 0.241744120773   ? -0.0873678843669 ? -0.230123422438  ? 0.0278146797776  ? 
0.343115520902   ? 0.0664075459759  ? -0.94265198845  ? 0.126742927724    ? 
2 'X-RAY DIFFRACTION' ? refined -11.2256662805 -0.742209044801 22.1424125612 0.170222744292 ? 0.0625232153346   ? 
-0.00017984977772 ? 0.242553374906  ? 0.000281497103685 ? 0.18284344487  ? 0.188990265482 ? -0.107936246471 ? 0.128131361487 ? 
2.73695685888 ? 0.695706308531 ? 1.53447404629 ? -0.0198387027973 ? -0.0232272448636 ? 0.0429870937682  ? -0.0419702384479 ? 
-0.104129369937  ? 0.249084450295   ? -0.222980066731  ? -0.609345306899 ? 0.0451075698255   ? 
3 'X-RAY DIFFRACTION' ? refined 2.4275550753   16.0458032972   34.4436598695 0.571609201401 ? -0.002128401172   ? 0.00513857270541 
? 0.25084315079   ? -0.023207984059   ? 0.2676855949   ? 3.13936457931  ? -1.95368287207  ? -3.44053840006 ? 2.71745950905 ? 
1.54190996853  ? 4.99943093135 ? -0.138807429276  ? -0.743977955783  ? 0.569627864319   ? 0.16940981933    ? 0.265799658721   ? 
-0.200012124168  ? -0.927244039369  ? 0.160767952249  ? -0.147057692052   ? 
4 'X-RAY DIFFRACTION' ? refined 2.92135110327  8.7870250273    27.4822620773 0.299514980422 ? -0.0228273139266  ? 0.0291805474897 
? 0.110627353657  ? -0.00615084414    ? 0.19610115602  ? 0.206393002149 ? 0.0649116523649 ? 0.378797535104 ? 1.5777624781  ? 
0.353036285204 ? 2.88875041818 ? -0.0574317214731 ? -0.0218151528237 ? 0.125409609474   ? -0.122793869058  ? 0.113653520965   ? 
-0.186596771377  ? -0.743892649475  ? 0.101534064973  ? -0.00637141583485 ? 
5 'X-RAY DIFFRACTION' ? refined -1.28501788334 -7.57894585001  27.4315346477 0.135853626949 ? -0.00160645455015 ? -0.0268609474134 
? 0.0851749790032 ? 0.0188038138581   ? 0.150466118261 ? 2.88783136513  ? -2.04165778287  ? 0.40848351239  ? 3.83204312212 ? 
1.52520301382  ? 3.9664305391  ? 0.161935256412   ? -0.0279576925085 ? -0.305302692797  ? 0.10447765187    ? -0.0081388799807 ? 
-0.0270163945101 ? 0.156005965138   ? -0.111019426816 ? -0.12737449369    ? 
6 'X-RAY DIFFRACTION' ? refined -15.1176979507 -1.07595223663  22.1998162415 0.149080356807 ? 0.0744418084933   ? -0.020218114844 
? 0.348485471858  ? -0.0171623882557  ? 0.192829376065 ? 2.21085512024  ? -3.82980659807  ? 0.41603993453  ? 7.58194730266 ? 
-0.84427512898 ? 1.20019203127 ? -0.0248905345382 ? 0.0452493435944  ? -0.0921104965393 ? -0.0876394175384 ? -0.0905121237419 ? 
0.365781111792   ? -0.0960573820931 ? -0.774544502617 ? 0.0418390687825   ? 
7 'X-RAY DIFFRACTION' ? refined -9.07643228268 7.10122149455   15.4128826993 0.471696802269 ? 0.201169289235    ? -0.0394327814798 
? 0.170243309927  ? 0.0380590237413   ? 0.182269943199 ? 0.805582103788 ? -0.270409561752 ? 0.339899598782 ? 1.65703527122 ? 
0.731389255196 ? 1.50739833468 ? -0.0529866418881 ? 0.0226834379617  ? 0.173625171868   ? -0.498311844434  ? 0.0342366022224  ? 
0.0913388376606  ? -0.882425275356  ? -0.329559497824 ? 0.0644788389863   ? 
8 'X-RAY DIFFRACTION' ? refined -13.4208009896 0.246618072664  11.7105555176 0.380747662777 ? 0.282937457867    ? -0.113891401434 
? 0.36898120335   ? 0.0043974848241   ? 0.251955652561 ? 5.81946430548  ? -1.86523165972  ? 1.60071785875  ? 2.43953341966 ? 
-1.08650903619 ? 1.12323868482 ? -0.134084119973  ? 0.398804562323   ? 0.302373835837   ? -0.41505115527   ? -0.200565629399  ? 
0.214355037893   ? -0.73098649007   ? -0.726829979152 ? -0.185368763607   ? 
9 'X-RAY DIFFRACTION' ? refined -1.68901574826 -7.19368129091  7.49331772676 0.205032913704 ? 0.0190662747925   ? 0.0307839374706 
? 0.150194707792  ? -0.0171419082961  ? 0.141281708562 ? 7.97623860999  ? -4.15729201063  ? 3.25114983077  ? 6.25599135804 ? 
-1.46238819205 ? 6.73767183097 ? 0.0360521453372  ? 0.344373488316   ? 0.150706646011   ? -0.301896550639  ? -0.0943693675045 ? 
-0.396294691261  ? -0.140588817071  ? 0.165424149526  ? 0.0671415782897   ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 A 1   A 28  ? A 24  A 51  ? ? 
;chain 'A' and (resid 28 through 51 )
;
2 'X-RAY DIFFRACTION' 2 A 25  A 52  ? A 58  A 85  ? ? 
;chain 'A' and (resid 52 through 85 )
;
3 'X-RAY DIFFRACTION' 3 A 59  A 86  ? A 74  A 101 ? ? 
;chain 'A' and (resid 86 through 101 )
;
4 'X-RAY DIFFRACTION' 4 A 75  A 102 ? A 128 A 155 ? ? 
;chain 'A' and (resid 102 through 155 )
;
5 'X-RAY DIFFRACTION' 5 A 129 A 156 ? A 152 A 179 ? ? 
;chain 'A' and (resid 156 through 179 )
;
6 'X-RAY DIFFRACTION' 6 A 153 A 180 ? A 167 A 194 ? ? 
;chain 'A' and (resid 180 through 194 )
;
7 'X-RAY DIFFRACTION' 7 A 168 A 195 ? A 223 A 250 ? ? 
;chain 'A' and (resid 195 through 250 )
;
8 'X-RAY DIFFRACTION' 8 A 224 A 251 ? A 237 A 264 ? ? 
;chain 'A' and (resid 251 through 264 )
;
9 'X-RAY DIFFRACTION' 9 A 238 A 265 ? A 260 A 287 ? ? 
;chain 'A' and (resid 265 through 287 )
;
# 
_pdbx_unobs_or_zero_occ_residues.id               1 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_residues.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id     A 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id     LEU 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id      288 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_residues.label_asym_id    A 
_pdbx_unobs_or_zero_occ_residues.label_comp_id    LEU 
_pdbx_unobs_or_zero_occ_residues.label_seq_id     261 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
SO4 S    S N N 304 
SO4 O1   O N N 305 
SO4 O2   O N N 306 
SO4 O3   O N N 307 
SO4 O4   O N N 308 
THR N    N N N 309 
THR CA   C N S 310 
THR C    C N N 311 
THR O    O N N 312 
THR CB   C N R 313 
THR OG1  O N N 314 
THR CG2  C N N 315 
THR OXT  O N N 316 
THR H    H N N 317 
THR H2   H N N 318 
THR HA   H N N 319 
THR HB   H N N 320 
THR HG1  H N N 321 
THR HG21 H N N 322 
THR HG22 H N N 323 
THR HG23 H N N 324 
THR HXT  H N N 325 
TRP N    N N N 326 
TRP CA   C N S 327 
TRP C    C N N 328 
TRP O    O N N 329 
TRP CB   C N N 330 
TRP CG   C Y N 331 
TRP CD1  C Y N 332 
TRP CD2  C Y N 333 
TRP NE1  N Y N 334 
TRP CE2  C Y N 335 
TRP CE3  C Y N 336 
TRP CZ2  C Y N 337 
TRP CZ3  C Y N 338 
TRP CH2  C Y N 339 
TRP OXT  O N N 340 
TRP H    H N N 341 
TRP H2   H N N 342 
TRP HA   H N N 343 
TRP HB2  H N N 344 
TRP HB3  H N N 345 
TRP HD1  H N N 346 
TRP HE1  H N N 347 
TRP HE3  H N N 348 
TRP HZ2  H N N 349 
TRP HZ3  H N N 350 
TRP HH2  H N N 351 
TRP HXT  H N N 352 
TYR N    N N N 353 
TYR CA   C N S 354 
TYR C    C N N 355 
TYR O    O N N 356 
TYR CB   C N N 357 
TYR CG   C Y N 358 
TYR CD1  C Y N 359 
TYR CD2  C Y N 360 
TYR CE1  C Y N 361 
TYR CE2  C Y N 362 
TYR CZ   C Y N 363 
TYR OH   O N N 364 
TYR OXT  O N N 365 
TYR H    H N N 366 
TYR H2   H N N 367 
TYR HA   H N N 368 
TYR HB2  H N N 369 
TYR HB3  H N N 370 
TYR HD1  H N N 371 
TYR HD2  H N N 372 
TYR HE1  H N N 373 
TYR HE2  H N N 374 
TYR HH   H N N 375 
TYR HXT  H N N 376 
VAL N    N N N 377 
VAL CA   C N S 378 
VAL C    C N N 379 
VAL O    O N N 380 
VAL CB   C N N 381 
VAL CG1  C N N 382 
VAL CG2  C N N 383 
VAL OXT  O N N 384 
VAL H    H N N 385 
VAL H2   H N N 386 
VAL HA   H N N 387 
VAL HB   H N N 388 
VAL HG11 H N N 389 
VAL HG12 H N N 390 
VAL HG13 H N N 391 
VAL HG21 H N N 392 
VAL HG22 H N N 393 
VAL HG23 H N N 394 
VAL HXT  H N N 395 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
SO4 S   O1   doub N N 290 
SO4 S   O2   doub N N 291 
SO4 S   O3   sing N N 292 
SO4 S   O4   sing N N 293 
THR N   CA   sing N N 294 
THR N   H    sing N N 295 
THR N   H2   sing N N 296 
THR CA  C    sing N N 297 
THR CA  CB   sing N N 298 
THR CA  HA   sing N N 299 
THR C   O    doub N N 300 
THR C   OXT  sing N N 301 
THR CB  OG1  sing N N 302 
THR CB  CG2  sing N N 303 
THR CB  HB   sing N N 304 
THR OG1 HG1  sing N N 305 
THR CG2 HG21 sing N N 306 
THR CG2 HG22 sing N N 307 
THR CG2 HG23 sing N N 308 
THR OXT HXT  sing N N 309 
TRP N   CA   sing N N 310 
TRP N   H    sing N N 311 
TRP N   H2   sing N N 312 
TRP CA  C    sing N N 313 
TRP CA  CB   sing N N 314 
TRP CA  HA   sing N N 315 
TRP C   O    doub N N 316 
TRP C   OXT  sing N N 317 
TRP CB  CG   sing N N 318 
TRP CB  HB2  sing N N 319 
TRP CB  HB3  sing N N 320 
TRP CG  CD1  doub Y N 321 
TRP CG  CD2  sing Y N 322 
TRP CD1 NE1  sing Y N 323 
TRP CD1 HD1  sing N N 324 
TRP CD2 CE2  doub Y N 325 
TRP CD2 CE3  sing Y N 326 
TRP NE1 CE2  sing Y N 327 
TRP NE1 HE1  sing N N 328 
TRP CE2 CZ2  sing Y N 329 
TRP CE3 CZ3  doub Y N 330 
TRP CE3 HE3  sing N N 331 
TRP CZ2 CH2  doub Y N 332 
TRP CZ2 HZ2  sing N N 333 
TRP CZ3 CH2  sing Y N 334 
TRP CZ3 HZ3  sing N N 335 
TRP CH2 HH2  sing N N 336 
TRP OXT HXT  sing N N 337 
TYR N   CA   sing N N 338 
TYR N   H    sing N N 339 
TYR N   H2   sing N N 340 
TYR CA  C    sing N N 341 
TYR CA  CB   sing N N 342 
TYR CA  HA   sing N N 343 
TYR C   O    doub N N 344 
TYR C   OXT  sing N N 345 
TYR CB  CG   sing N N 346 
TYR CB  HB2  sing N N 347 
TYR CB  HB3  sing N N 348 
TYR CG  CD1  doub Y N 349 
TYR CG  CD2  sing Y N 350 
TYR CD1 CE1  sing Y N 351 
TYR CD1 HD1  sing N N 352 
TYR CD2 CE2  doub Y N 353 
TYR CD2 HD2  sing N N 354 
TYR CE1 CZ   doub Y N 355 
TYR CE1 HE1  sing N N 356 
TYR CE2 CZ   sing Y N 357 
TYR CE2 HE2  sing N N 358 
TYR CZ  OH   sing N N 359 
TYR OH  HH   sing N N 360 
TYR OXT HXT  sing N N 361 
VAL N   CA   sing N N 362 
VAL N   H    sing N N 363 
VAL N   H2   sing N N 364 
VAL CA  C    sing N N 365 
VAL CA  CB   sing N N 366 
VAL CA  HA   sing N N 367 
VAL C   O    doub N N 368 
VAL C   OXT  sing N N 369 
VAL CB  CG1  sing N N 370 
VAL CB  CG2  sing N N 371 
VAL CB  HB   sing N N 372 
VAL CG1 HG11 sing N N 373 
VAL CG1 HG12 sing N N 374 
VAL CG1 HG13 sing N N 375 
VAL CG2 HG21 sing N N 376 
VAL CG2 HG22 sing N N 377 
VAL CG2 HG23 sing N N 378 
VAL OXT HXT  sing N N 379 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'German Research Foundation (DFG)'                        Germany 458246365 1 
'German Research Foundation (DFG)'                        Germany 451079909 2 
'German Federal Ministry for Economic Affairs and Energy' Germany 01KI2114  3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6GTH 
_pdbx_initial_refinement_model.details          ? 
# 
_pdbx_serial_crystallography_sample_delivery.diffrn_id     1 
_pdbx_serial_crystallography_sample_delivery.description   ? 
_pdbx_serial_crystallography_sample_delivery.method        'fixed target' 
# 
_space_group.name_H-M_alt     'P 43 21 2' 
_space_group.name_Hall        'P 4nw 2abw' 
_space_group.IT_number        96 
_space_group.crystal_system   tetragonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    8REM 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.023725 
_atom_sites.fract_transf_matrix[1][2]   0.013698 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.027395 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.004270 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CL ? ? 9.50761 7.44341 ? ? 1.04373  23.83732 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
NA ? ? 9.38062 1.54875 ? ? 3.38349  72.32734 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . SER A 1 1   ? -22.18240 -14.64018 5.50073  1.000 59.54486 ? 28  SER A N   1 
ATOM   2    C CA  . SER A 1 1   ? -22.44873 -13.47541 4.65923  1.000 58.03942 ? 28  SER A CA  1 
ATOM   3    C C   . SER A 1 1   ? -21.30860 -13.20508 3.68523  1.000 52.80408 ? 28  SER A C   1 
ATOM   4    O O   . SER A 1 1   ? -20.19485 -13.70314 3.86251  1.000 51.67593 ? 28  SER A O   1 
ATOM   5    C CB  . SER A 1 1   ? -22.67682 -12.23313 5.51822  1.000 57.23630 ? 28  SER A CB  1 
ATOM   6    O OG  . SER A 1 1   ? -21.44351 -11.75257 6.03658  1.000 55.83594 ? 28  SER A OG  1 
ATOM   7    N N   . ALA A 1 2   ? -21.59048 -12.37530 2.67821  1.000 56.12343 ? 29  ALA A N   1 
ATOM   8    C CA  . ALA A 1 2   ? -20.60844 -12.09013 1.63469  1.000 50.46428 ? 29  ALA A CA  1 
ATOM   9    C C   . ALA A 1 2   ? -19.35478 -11.43577 2.19731  1.000 38.64539 ? 29  ALA A C   1 
ATOM   10   O O   . ALA A 1 2   ? -18.23438 -11.75555 1.77659  1.000 38.01876 ? 29  ALA A O   1 
ATOM   11   C CB  . ALA A 1 2   ? -21.22961 -11.18866 0.56884  1.000 50.27543 ? 29  ALA A CB  1 
ATOM   12   N N   A VAL A 1 3   ? -19.51927 -10.50588 3.14024  0.227 38.21435 ? 30  VAL A N   1 
ATOM   13   N N   B VAL A 1 3   ? -19.52173 -10.49614 3.12702  0.773 38.07260 ? 30  VAL A N   1 
ATOM   14   C CA  A VAL A 1 3   ? -18.35649 -9.81933  3.69022  0.227 33.38492 ? 30  VAL A CA  1 
ATOM   15   C CA  B VAL A 1 3   ? -18.35936 -9.82784  3.69787  0.773 33.07907 ? 30  VAL A CA  1 
ATOM   16   C C   A VAL A 1 3   ? -17.51931 -10.76734 4.53634  0.227 34.66955 ? 30  VAL A C   1 
ATOM   17   C C   B VAL A 1 3   ? -17.51019 -10.82284 4.47089  0.773 34.61165 ? 30  VAL A C   1 
ATOM   18   O O   A VAL A 1 3   ? -16.29158 -10.63289 4.59704  0.227 32.47413 ? 30  VAL A O   1 
ATOM   19   O O   B VAL A 1 3   ? -16.27646 -10.77065 4.43092  0.773 32.71132 ? 30  VAL A O   1 
ATOM   20   C CB  A VAL A 1 3   ? -18.79280 -8.57853  4.48937  0.227 37.13863 ? 30  VAL A CB  1 
ATOM   21   C CB  B VAL A 1 3   ? -18.80412 -8.65093  4.58026  0.773 37.02883 ? 30  VAL A CB  1 
ATOM   22   C CG1 A VAL A 1 3   ? -19.33495 -7.51270  3.55062  0.227 43.66515 ? 30  VAL A CG1 1 
ATOM   23   C CG1 B VAL A 1 3   ? -17.61178 -8.02086  5.29372  0.773 38.70880 ? 30  VAL A CG1 1 
ATOM   24   C CG2 A VAL A 1 3   ? -19.83808 -8.95385  5.53430  0.227 41.64683 ? 30  VAL A CG2 1 
ATOM   25   C CG2 B VAL A 1 3   ? -19.56076 -7.62779  3.74792  0.773 44.18792 ? 30  VAL A CG2 1 
ATOM   26   N N   . GLN A 1 4   ? -18.15287 -11.73806 5.19929  1.000 34.20361 ? 31  GLN A N   1 
ATOM   27   C CA  . GLN A 1 4   ? -17.38636 -12.68106 6.01170  1.000 33.80286 ? 31  GLN A CA  1 
ATOM   28   C C   . GLN A 1 4   ? -16.61578 -13.66183 5.14077  1.000 29.06140 ? 31  GLN A C   1 
ATOM   29   O O   . GLN A 1 4   ? -15.49375 -14.04302 5.49910  1.000 29.66870 ? 31  GLN A O   1 
ATOM   30   C CB  . GLN A 1 4   ? -18.30497 -13.41697 6.99158  1.000 38.59890 ? 31  GLN A CB  1 
ATOM   31   C CG  . GLN A 1 4   ? -18.43298 -12.68421 8.30232  1.000 37.09874 ? 31  GLN A CG  1 
ATOM   32   C CD  . GLN A 1 4   ? -19.65793 -13.07397 9.05161  1.000 54.68980 ? 31  GLN A CD  1 
ATOM   33   O OE1 . GLN A 1 4   ? -20.46359 -13.88566 8.57981  1.000 56.17192 ? 31  GLN A OE1 1 
ATOM   34   N NE2 . GLN A 1 4   ? -19.82739 -12.49393 10.23088 1.000 50.68659 ? 31  GLN A NE2 1 
ATOM   35   N N   . GLN A 1 5   ? -17.17425 -14.04280 3.98681  1.000 31.76159 ? 32  GLN A N   1 
ATOM   36   C CA  . GLN A 1 5   ? -16.44168 -14.89353 3.05306  1.000 36.26853 ? 32  GLN A CA  1 
ATOM   37   C C   . GLN A 1 5   ? -15.22673 -14.16325 2.48617  1.000 31.84934 ? 32  GLN A C   1 
ATOM   38   O O   . GLN A 1 5   ? -14.14818 -14.75557 2.33161  1.000 29.59924 ? 32  GLN A O   1 
ATOM   39   C CB  . GLN A 1 5   ? -17.36040 -15.34638 1.91629  1.000 42.51303 ? 32  GLN A CB  1 
ATOM   40   C CG  . GLN A 1 5   ? -18.39189 -16.39019 2.30782  1.000 60.18437 ? 32  GLN A CG  1 
ATOM   41   C CD  . GLN A 1 5   ? -17.83710 -17.80542 2.26246  1.000 84.20375 ? 32  GLN A CD  1 
ATOM   42   O OE1 . GLN A 1 5   ? -17.49053 -18.31368 1.19286  1.000 93.49678 ? 32  GLN A OE1 1 
ATOM   43   N NE2 . GLN A 1 5   ? -17.75033 -18.44963 3.42636  1.000 83.44475 ? 32  GLN A NE2 1 
ATOM   44   N N   . LYS A 1 6   ? -15.38890 -12.87971 2.15013  1.000 28.47400 ? 33  LYS A N   1 
ATOM   45   C CA  . LYS A 1 6   ? -14.25529 -12.12878 1.62218  1.000 26.85924 ? 33  LYS A CA  1 
ATOM   46   C C   . LYS A 1 6   ? -13.19399 -11.90495 2.69412  1.000 27.85401 ? 33  LYS A C   1 
ATOM   47   O O   . LYS A 1 6   ? -11.99298 -11.97595 2.40151  1.000 24.97554 ? 33  LYS A O   1 
ATOM   48   C CB  . LYS A 1 6   ? -14.72264 -10.79320 1.02964  1.000 25.88536 ? 33  LYS A CB  1 
ATOM   49   C CG  . LYS A 1 6   ? -15.35957 -10.88695 -0.34157 1.000 31.86527 ? 33  LYS A CG  1 
ATOM   50   C CD  . LYS A 1 6   ? -15.80423 -9.49689  -0.79047 1.000 36.07557 ? 33  LYS A CD  1 
ATOM   51   C CE  . LYS A 1 6   ? -16.03198 -9.39152  -2.28442 1.000 43.65171 ? 33  LYS A CE  1 
ATOM   52   N NZ  . LYS A 1 6   ? -16.67295 -8.08498  -2.55751 1.000 65.90596 ? 33  LYS A NZ  1 
ATOM   53   N N   . LEU A 1 7   ? -13.59946 -11.62747 3.95180  1.000 22.49610 ? 34  LEU A N   1 
ATOM   54   C CA  . LEU A 1 7   ? -12.59910 -11.50311 4.98932  1.000 18.73607 ? 34  LEU A CA  1 
ATOM   55   C C   . LEU A 1 7   ? -11.86824 -12.82680 5.22642  1.000 20.52412 ? 34  LEU A C   1 
ATOM   56   O O   . LEU A 1 7   ? -10.65330 -12.82850 5.46153  1.000 20.36117 ? 34  LEU A O   1 
ATOM   57   C CB  . LEU A 1 7   ? -13.20963 -10.99766 6.31241  1.000 19.92347 ? 34  LEU A CB  1 
ATOM   58   C CG  . LEU A 1 7   ? -13.75157 -9.56624  6.24212  1.000 24.67398 ? 34  LEU A CG  1 
ATOM   59   C CD1 . LEU A 1 7   ? -14.58477 -9.23890  7.48892  1.000 28.71608 ? 34  LEU A CD1 1 
ATOM   60   C CD2 . LEU A 1 7   ? -12.62444 -8.55254  6.11879  1.000 25.03832 ? 34  LEU A CD2 1 
ATOM   61   N N   . ALA A 1 8   ? -12.58508 -13.96188 5.17166  1.000 22.58369 ? 35  ALA A N   1 
ATOM   62   C CA  . ALA A 1 8   ? -11.90905 -15.24570 5.37710  1.000 21.79176 ? 35  ALA A CA  1 
ATOM   63   C C   . ALA A 1 8   ? -10.89645 -15.51399 4.26319  1.000 21.23741 ? 35  ALA A C   1 
ATOM   64   O O   . ALA A 1 8   ? -9.80929  -16.05289 4.52539  1.000 20.48925 ? 35  ALA A O   1 
ATOM   65   C CB  . ALA A 1 8   ? -12.92254 -16.40018 5.44718  1.000 25.88934 ? 35  ALA A CB  1 
ATOM   66   N N   . ALA A 1 9   ? -11.24532 -15.14416 3.01583  1.000 21.31194 ? 36  ALA A N   1 
ATOM   67   C CA  . ALA A 1 9   ? -10.32056 -15.28201 1.88744  1.000 22.52885 ? 36  ALA A CA  1 
ATOM   68   C C   . ALA A 1 9   ? -9.10844  -14.37978 2.08228  1.000 20.18032 ? 36  ALA A C   1 
ATOM   69   O O   . ALA A 1 9   ? -7.96431  -14.77841 1.80915  1.000 20.42003 ? 36  ALA A O   1 
ATOM   70   C CB  . ALA A 1 9   ? -11.01256 -14.95011 0.54314  1.000 21.11068 ? 36  ALA A CB  1 
ATOM   71   N N   . LEU A 1 10  ? -9.33922  -13.13568 2.51806  1.000 18.24738 ? 37  LEU A N   1 
ATOM   72   C CA  . LEU A 1 10  ? -8.20658  -12.24954 2.78547  1.000 16.42858 ? 37  LEU A CA  1 
ATOM   73   C C   . LEU A 1 10  ? -7.28481  -12.86355 3.82142  1.000 17.21881 ? 37  LEU A C   1 
ATOM   74   O O   . LEU A 1 10  ? -6.05813  -12.86898 3.65856  1.000 20.19623 ? 37  LEU A O   1 
ATOM   75   C CB  . LEU A 1 10  ? -8.69746  -10.88235 3.25813  1.000 19.65506 ? 37  LEU A CB  1 
ATOM   76   C CG  . LEU A 1 10  ? -7.58281  -9.95344  3.77555  1.000 19.02050 ? 37  LEU A CG  1 
ATOM   77   C CD1 . LEU A 1 10  ? -6.70229  -9.57916  2.61205  1.000 23.31273 ? 37  LEU A CD1 1 
ATOM   78   C CD2 . LEU A 1 10  ? -8.16542  -8.68353  4.42841  1.000 21.30286 ? 37  LEU A CD2 1 
ATOM   79   N N   . GLU A 1 11  ? -7.87089  -13.41261 4.88857  1.000 15.82506 ? 38  GLU A N   1 
ATOM   80   C CA  . GLU A 1 11  ? -7.07398  -14.01961 5.94519  1.000 17.39251 ? 38  GLU A CA  1 
ATOM   81   C C   . GLU A 1 11  ? -6.26026  -15.18299 5.40463  1.000 17.99642 ? 38  GLU A C   1 
ATOM   82   O O   . GLU A 1 11  ? -5.06644  -15.28422 5.68366  1.000 18.48022 ? 38  GLU A O   1 
ATOM   83   C CB  . GLU A 1 11  ? -7.98936  -14.47460 7.06472  1.000 14.02930 ? 38  GLU A CB  1 
ATOM   84   C CG  . GLU A 1 11  ? -7.21427  -15.00632 8.26087  1.000 17.90583 ? 38  GLU A CG  1 
ATOM   85   C CD  . GLU A 1 11  ? -8.13526  -15.55512 9.32008  1.000 19.90647 ? 38  GLU A CD  1 
ATOM   86   O OE1 . GLU A 1 11  ? -8.97744  -16.44966 9.00018  1.000 20.48810 ? 38  GLU A OE1 1 
ATOM   87   O OE2 . GLU A 1 11  ? -8.03763  -15.07020 10.48825 1.000 19.64596 ? 38  GLU A OE2 1 
ATOM   88   N N   . LYS A 1 12  ? -6.88309  -16.04114 4.59399  1.000 19.02612 ? 39  LYS A N   1 
ATOM   89   C CA  . LYS A 1 12  ? -6.17756  -17.18738 4.04127  1.000 21.52619 ? 39  LYS A CA  1 
ATOM   90   C C   . LYS A 1 12  ? -5.01037  -16.74086 3.18838  1.000 23.56327 ? 39  LYS A C   1 
ATOM   91   O O   . LYS A 1 12  ? -3.91393  -17.31759 3.26558  1.000 24.94047 ? 39  LYS A O   1 
ATOM   92   C CB  . LYS A 1 12  ? -7.14648  -18.05134 3.24102  1.000 20.72981 ? 39  LYS A CB  1 
ATOM   93   C CG  . LYS A 1 12  ? -6.57816  -19.43086 2.80359  1.000 27.24105 ? 39  LYS A CG  1 
ATOM   94   C CD  . LYS A 1 12  ? -7.62190  -20.21960 2.01734  1.000 44.20560 ? 39  LYS A CD  1 
ATOM   95   C CE  . LYS A 1 12  ? -7.09884  -21.59870 1.60056  1.000 50.48006 ? 39  LYS A CE  1 
ATOM   96   N NZ  . LYS A 1 12  ? -8.08870  -22.31716 0.73005  1.000 55.42557 ? 39  LYS A NZ  1 
ATOM   97   N N   . SER A 1 13  ? -5.20627  -15.68538 2.38203  1.000 16.72357 ? 40  SER A N   1 
ATOM   98   C CA  . SER A 1 13  ? -4.12298  -15.23162 1.51619  1.000 20.66526 ? 40  SER A CA  1 
ATOM   99   C C   . SER A 1 13  ? -2.97225  -14.62864 2.31288  1.000 22.03592 ? 40  SER A C   1 
ATOM   100  O O   . SER A 1 13  ? -1.84792  -14.61451 1.80613  1.000 24.16196 ? 40  SER A O   1 
ATOM   101  C CB  . SER A 1 13  ? -4.60959  -14.17829 0.51814  1.000 22.92810 ? 40  SER A CB  1 
ATOM   102  O OG  . SER A 1 13  ? -4.76970  -12.90580 1.15477  1.000 19.90889 ? 40  SER A OG  1 
ATOM   103  N N   . SER A 1 14  ? -3.22758  -14.16714 3.55523  1.000 22.73802 ? 41  SER A N   1 
ATOM   104  C CA  . SER A 1 14  ? -2.23568  -13.41629 4.31149  1.000 20.02404 ? 41  SER A CA  1 
ATOM   105  C C   . SER A 1 14  ? -1.32383  -14.29816 5.15539  1.000 21.80256 ? 41  SER A C   1 
ATOM   106  O O   . SER A 1 14  ? -0.26832  -13.82561 5.59516  1.000 27.19175 ? 41  SER A O   1 
ATOM   107  C CB  . SER A 1 14  ? -2.93534  -12.43483 5.27010  1.000 19.39788 ? 41  SER A CB  1 
ATOM   108  O OG  . SER A 1 14  ? -3.48656  -13.20851 6.34843  1.000 20.89809 ? 41  SER A OG  1 
ATOM   109  N N   . GLY A 1 15  ? -1.73666  -15.51417 5.45194  1.000 19.67324 ? 42  GLY A N   1 
ATOM   110  C CA  . GLY A 1 15  ? -1.00661  -16.42515 6.30206  1.000 22.01110 ? 42  GLY A CA  1 
ATOM   111  C C   . GLY A 1 15  ? -1.10737  -16.11599 7.78262  1.000 26.04653 ? 42  GLY A C   1 
ATOM   112  O O   . GLY A 1 15  ? -0.47078  -16.80777 8.59577  1.000 27.12267 ? 42  GLY A O   1 
ATOM   113  N N   . GLY A 1 16  ? -1.89624  -15.12777 8.15887  1.000 18.78143 ? 43  GLY A N   1 
ATOM   114  C CA  . GLY A 1 16  ? -2.01301  -14.77809 9.57534  1.000 18.09724 ? 43  GLY A CA  1 
ATOM   115  C C   . GLY A 1 16  ? -3.41700  -14.99248 10.11068 1.000 17.78046 ? 43  GLY A C   1 
ATOM   116  O O   . GLY A 1 16  ? -4.20284  -15.80650 9.59304  1.000 21.99436 ? 43  GLY A O   1 
ATOM   117  N N   . ARG A 1 17  ? -3.68417  -14.33815 11.23115 1.000 16.48395 ? 44  ARG A N   1 
ATOM   118  C CA  . ARG A 1 17  ? -4.94934  -14.42353 11.94066 1.000 17.00159 ? 44  ARG A CA  1 
ATOM   119  C C   . ARG A 1 17  ? -5.50699  -13.01221 12.04930 1.000 20.24295 ? 44  ARG A C   1 
ATOM   120  O O   . ARG A 1 17  ? -4.84034  -12.12041 12.60547 1.000 16.84169 ? 44  ARG A O   1 
ATOM   121  C CB  . ARG A 1 17  ? -4.76397  -15.05835 13.32779 1.000 16.36188 ? 44  ARG A CB  1 
ATOM   122  C CG  . ARG A 1 17  ? -6.08794  -15.19964 14.10062 1.000 18.04319 ? 44  ARG A CG  1 
ATOM   123  C CD  . ARG A 1 17  ? -5.94712  -15.98133 15.41823 1.000 18.63544 ? 44  ARG A CD  1 
ATOM   124  N NE  . ARG A 1 17  ? -5.07444  -15.31023 16.38034 1.000 20.13496 ? 44  ARG A NE  1 
ATOM   125  C CZ  . ARG A 1 17  ? -5.49824  -14.62908 17.43262 1.000 18.53075 ? 44  ARG A CZ  1 
ATOM   126  N NH1 . ARG A 1 17  ? -6.78589  -14.52386 17.73571 1.000 21.47934 ? 44  ARG A NH1 1 
ATOM   127  N NH2 . ARG A 1 17  ? -4.60657  -14.04326 18.22775 1.000 22.57563 ? 44  ARG A NH2 1 
ATOM   128  N N   . LEU A 1 18  ? -6.71428  -12.81606 11.50243 1.000 15.35330 ? 45  LEU A N   1 
ATOM   129  C CA  . LEU A 1 18  ? -7.33941  -11.50874 11.33580 1.000 15.52621 ? 45  LEU A CA  1 
ATOM   130  C C   . LEU A 1 18  ? -8.57924  -11.42076 12.22084 1.000 17.98986 ? 45  LEU A C   1 
ATOM   131  O O   . LEU A 1 18  ? -9.40651  -12.34449 12.23367 1.000 18.16534 ? 45  LEU A O   1 
ATOM   132  C CB  . LEU A 1 18  ? -7.71526  -11.31595 9.86480  1.000 15.51026 ? 45  LEU A CB  1 
ATOM   133  C CG  . LEU A 1 18  ? -8.52065  -10.07415 9.49059  1.000 16.64564 ? 45  LEU A CG  1 
ATOM   134  C CD1 . LEU A 1 18  ? -7.59850  -8.85761  9.56614  1.000 19.89824 ? 45  LEU A CD1 1 
ATOM   135  C CD2 . LEU A 1 18  ? -9.04663  -10.18512 8.05302  1.000 21.07217 ? 45  LEU A CD2 1 
ATOM   136  N N   . GLY A 1 19  ? -8.73125  -10.30740 12.93381 1.000 15.88956 ? 46  GLY A N   1 
ATOM   137  C CA  . GLY A 1 19  ? -9.93877  -10.06481 13.71509 1.000 18.61862 ? 46  GLY A CA  1 
ATOM   138  C C   . GLY A 1 19  ? -10.53133 -8.70705  13.35575 1.000 21.47953 ? 46  GLY A C   1 
ATOM   139  O O   . GLY A 1 19  ? -9.80915  -7.70955  13.30379 1.000 20.77747 ? 46  GLY A O   1 
ATOM   140  N N   . VAL A 1 20  ? -11.82166 -8.65213  13.08437 1.000 18.30127 ? 47  VAL A N   1 
ATOM   141  C CA  . VAL A 1 20  ? -12.49455 -7.44545  12.59786 1.000 17.80049 ? 47  VAL A CA  1 
ATOM   142  C C   . VAL A 1 20  ? -13.76948 -7.24825  13.39877 1.000 23.17930 ? 47  VAL A C   1 
ATOM   143  O O   . VAL A 1 20  ? -14.51458 -8.20518  13.63742 1.000 25.17001 ? 47  VAL A O   1 
ATOM   144  C CB  . VAL A 1 20  ? -12.84628 -7.53489  11.09531 1.000 20.16788 ? 47  VAL A CB  1 
ATOM   145  C CG1 . VAL A 1 20  ? -13.57282 -6.23258  10.62341 1.000 22.55783 ? 47  VAL A CG1 1 
ATOM   146  C CG2 . VAL A 1 20  ? -11.61981 -7.77008  10.29582 1.000 19.87046 ? 47  VAL A CG2 1 
ATOM   147  N N   . ALA A 1 21  ? -14.03876 -6.00852  13.80987 1.000 20.91551 ? 48  ALA A N   1 
ATOM   148  C CA  . ALA A 1 21  ? -15.37427 -5.68570  14.28794 1.000 21.38446 ? 48  ALA A CA  1 
ATOM   149  C C   . ALA A 1 21  ? -15.76271 -4.33695  13.72290 1.000 21.69389 ? 48  ALA A C   1 
ATOM   150  O O   . ALA A 1 21  ? -14.99624 -3.37138  13.82224 1.000 25.78828 ? 48  ALA A O   1 
ATOM   151  C CB  . ALA A 1 21  ? -15.44086 -5.66016  15.82165 1.000 21.88812 ? 48  ALA A CB  1 
ATOM   152  N N   . LEU A 1 22  ? -16.96380 -4.28406  13.15506 1.000 21.46212 ? 49  LEU A N   1 
ATOM   153  C CA  . LEU A 1 22  ? -17.56479 -3.06227  12.64350 1.000 24.96434 ? 49  LEU A CA  1 
ATOM   154  C C   . LEU A 1 22  ? -18.85441 -2.82522  13.41249 1.000 27.46597 ? 49  LEU A C   1 
ATOM   155  O O   . LEU A 1 22  ? -19.63293 -3.76201  13.62407 1.000 29.49511 ? 49  LEU A O   1 
ATOM   156  C CB  . LEU A 1 22  ? -17.87171 -3.17236  11.13286 1.000 25.00040 ? 49  LEU A CB  1 
ATOM   157  C CG  . LEU A 1 22  ? -18.72530 -1.99651  10.63198 1.000 28.79225 ? 49  LEU A CG  1 
ATOM   158  C CD1 . LEU A 1 22  ? -17.84147 -0.82569  10.18709 1.000 31.81192 ? 49  LEU A CD1 1 
ATOM   159  C CD2 . LEU A 1 22  ? -19.59971 -2.46195  9.50817  1.000 36.63688 ? 49  LEU A CD2 1 
ATOM   160  N N   . ILE A 1 23  ? -19.06369 -1.59874  13.87815 1.000 26.11323 ? 50  ILE A N   1 
ATOM   161  C CA  . ILE A 1 23  ? -20.37360 -1.18192  14.38094 1.000 27.66907 ? 50  ILE A CA  1 
ATOM   162  C C   . ILE A 1 23  ? -20.84299 -0.06088  13.48224 1.000 30.39129 ? 50  ILE A C   1 
ATOM   163  O O   . ILE A 1 23  ? -20.11881 0.91737   13.26692 1.000 31.20113 ? 50  ILE A O   1 
ATOM   164  C CB  . ILE A 1 23  ? -20.34251 -0.73865  15.84984 1.000 30.96262 ? 50  ILE A CB  1 
ATOM   165  C CG1 . ILE A 1 23  ? -19.81955 -1.88956  16.69850 1.000 27.49134 ? 50  ILE A CG1 1 
ATOM   166  C CG2 . ILE A 1 23  ? -21.76537 -0.23978  16.27033 1.000 33.52633 ? 50  ILE A CG2 1 
ATOM   167  C CD1 . ILE A 1 23  ? -19.39322 -1.47007  18.12321 1.000 36.78216 ? 50  ILE A CD1 1 
ATOM   168  N N   . ASP A 1 24  ? -22.02060 -0.23014  12.90493 1.000 30.97975 ? 51  ASP A N   1 
ATOM   169  C CA  . ASP A 1 24  ? -22.65303 0.80190   12.10602 1.000 36.91412 ? 51  ASP A CA  1 
ATOM   170  C C   . ASP A 1 24  ? -23.62246 1.53409   13.03275 1.000 37.42956 ? 51  ASP A C   1 
ATOM   171  O O   . ASP A 1 24  ? -24.60504 0.94527   13.48497 1.000 38.92185 ? 51  ASP A O   1 
ATOM   172  C CB  . ASP A 1 24  ? -23.36302 0.16861   10.90641 1.000 38.05596 ? 51  ASP A CB  1 
ATOM   173  C CG  . ASP A 1 24  ? -23.94608 1.19776   9.97478  1.000 52.59698 ? 51  ASP A CG  1 
ATOM   174  O OD1 . ASP A 1 24  ? -24.12270 2.34310   10.43137 1.000 44.79495 ? 51  ASP A OD1 1 
ATOM   175  O OD2 . ASP A 1 24  ? -24.22101 0.87376   8.79318  1.000 46.24861 ? 51  ASP A OD2 1 
ATOM   176  N N   . THR A 1 25  ? -23.33070 2.80215   13.35214 1.000 41.97397 ? 52  THR A N   1 
ATOM   177  C CA  . THR A 1 25  ? -24.17692 3.49854   14.32313 1.000 39.54042 ? 52  THR A CA  1 
ATOM   178  C C   . THR A 1 25  ? -25.51357 3.93470   13.72806 1.000 45.36925 ? 52  THR A C   1 
ATOM   179  O O   . THR A 1 25  ? -26.35346 4.47649   14.45790 1.000 56.14578 ? 52  THR A O   1 
ATOM   180  C CB  . THR A 1 25  ? -23.44965 4.71195   14.93762 1.000 37.82501 ? 52  THR A CB  1 
ATOM   181  O OG1 . THR A 1 25  ? -23.29486 5.76364   13.97613 1.000 43.42371 ? 52  THR A OG1 1 
ATOM   182  C CG2 . THR A 1 25  ? -22.05631 4.31577   15.48939 1.000 33.58880 ? 52  THR A CG2 1 
ATOM   183  N N   . ALA A 1 26  ? -25.74459 3.68081   12.43739 1.000 42.06678 ? 53  ALA A N   1 
ATOM   184  C CA  . ALA A 1 26  ? -27.03254 4.03075   11.83624 1.000 44.00213 ? 53  ALA A CA  1 
ATOM   185  C C   . ALA A 1 26  ? -28.15240 3.13995   12.37187 1.000 55.75265 ? 53  ALA A C   1 
ATOM   186  O O   . ALA A 1 26  ? -29.24906 3.62496   12.68229 1.000 60.02010 ? 53  ALA A O   1 
ATOM   187  C CB  . ALA A 1 26  ? -26.93351 3.93205   10.31125 1.000 43.54655 ? 53  ALA A CB  1 
ATOM   188  N N   . ASP A 1 27  ? -27.89918 1.83305   12.48423 1.000 49.38557 ? 54  ASP A N   1 
ATOM   189  C CA  . ASP A 1 27  ? -28.88310 0.88013   12.98484 1.000 54.07393 ? 54  ASP A CA  1 
ATOM   190  C C   . ASP A 1 27  ? -28.31212 -0.02450  14.06984 1.000 53.80541 ? 54  ASP A C   1 
ATOM   191  O O   . ASP A 1 27  ? -28.93919 -1.03962  14.40514 1.000 53.80136 ? 54  ASP A O   1 
ATOM   192  C CB  . ASP A 1 27  ? -29.43201 0.03300   11.83320 1.000 52.19471 ? 54  ASP A CB  1 
ATOM   193  C CG  . ASP A 1 27  ? -28.33543 -0.47842  10.92972 1.000 60.99678 ? 54  ASP A CG  1 
ATOM   194  O OD1 . ASP A 1 27  ? -27.15388 -0.39548  11.32886 1.000 49.96580 ? 54  ASP A OD1 1 
ATOM   195  O OD2 . ASP A 1 27  ? -28.63496 -0.95883  9.82550  1.000 56.30467 ? 54  ASP A OD2 1 
ATOM   196  N N   . ASN A 1 28  ? -27.13367 0.31140   14.60942 1.000 51.25907 ? 55  ASN A N   1 
ATOM   197  C CA  . ASN A 1 28  ? -26.45781 -0.46728  15.64832 1.000 51.37186 ? 55  ASN A CA  1 
ATOM   198  C C   . ASN A 1 28  ? -26.19405 -1.90032  15.21153 1.000 51.82310 ? 55  ASN A C   1 
ATOM   199  O O   . ASN A 1 28  ? -26.11506 -2.80624  16.04286 1.000 62.14514 ? 55  ASN A O   1 
ATOM   200  C CB  . ASN A 1 28  ? -27.23842 -0.45449  16.96244 1.000 52.69862 ? 55  ASN A CB  1 
ATOM   201  C CG  . ASN A 1 28  ? -27.33871 0.93049   17.55251 1.000 72.67708 ? 55  ASN A CG  1 
ATOM   202  O OD1 . ASN A 1 28  ? -26.47922 1.78092   17.30726 1.000 64.35833 ? 55  ASN A OD1 1 
ATOM   203  N ND2 . ASN A 1 28  ? -28.39793 1.17611   18.32156 1.000 74.13290 ? 55  ASN A ND2 1 
ATOM   204  N N   . THR A 1 29  ? -26.07174 -2.12309  13.91051 1.000 51.53393 ? 56  THR A N   1 
ATOM   205  C CA  . THR A 1 29  ? -25.71036 -3.44827  13.44777 1.000 41.55412 ? 56  THR A CA  1 
ATOM   206  C C   . THR A 1 29  ? -24.20361 -3.63388  13.56539 1.000 36.72637 ? 56  THR A C   1 
ATOM   207  O O   . THR A 1 29  ? -23.43793 -2.67062  13.71519 1.000 38.46059 ? 56  THR A O   1 
ATOM   208  C CB  . THR A 1 29  ? -26.16119 -3.67710  12.00593 1.000 44.83533 ? 56  THR A CB  1 
ATOM   209  O OG1 . THR A 1 29  ? -25.56748 -2.68417  11.15615 1.000 47.02437 ? 56  THR A OG1 1 
ATOM   210  C CG2 . THR A 1 29  ? -27.69955 -3.61477  11.90366 1.000 50.80471 ? 56  THR A CG2 1 
ATOM   211  N N   . GLN A 1 30  ? -23.79165 -4.89441  13.55077 1.000 36.34272 ? 57  GLN A N   1 
ATOM   212  C CA  . GLN A 1 30  ? -22.40226 -5.25968  13.77311 1.000 38.85074 ? 57  GLN A CA  1 
ATOM   213  C C   . GLN A 1 30  ? -21.97561 -6.27591  12.73238 1.000 38.21647 ? 57  GLN A C   1 
ATOM   214  O O   . GLN A 1 30  ? -22.77032 -7.11038  12.28569 1.000 41.79496 ? 57  GLN A O   1 
ATOM   215  C CB  . GLN A 1 30  ? -22.17156 -5.85303  15.17029 1.000 38.16907 ? 57  GLN A CB  1 
ATOM   216  C CG  . GLN A 1 30  ? -22.35720 -4.86609  16.29982 1.000 44.79506 ? 57  GLN A CG  1 
ATOM   217  C CD  . GLN A 1 30  ? -21.98107 -5.43728  17.65695 1.000 58.30742 ? 57  GLN A CD  1 
ATOM   218  O OE1 . GLN A 1 30  ? -21.43568 -6.53708  17.75707 1.000 51.41028 ? 57  GLN A OE1 1 
ATOM   219  N NE2 . GLN A 1 30  ? -22.27462 -4.68160  18.71782 1.000 66.98954 ? 57  GLN A NE2 1 
ATOM   220  N N   . VAL A 1 31  ? -20.71305 -6.19739  12.33439 1.000 30.70920 ? 58  VAL A N   1 
ATOM   221  C CA  . VAL A 1 31  ? -20.11336 -7.22577  11.49662 1.000 28.10137 ? 58  VAL A CA  1 
ATOM   222  C C   . VAL A 1 31  ? -18.85536 -7.68564  12.21365 1.000 28.56282 ? 58  VAL A C   1 
ATOM   223  O O   . VAL A 1 31  ? -18.03190 -6.85342  12.60405 1.000 30.24606 ? 58  VAL A O   1 
ATOM   224  C CB  . VAL A 1 31  ? -19.77295 -6.71145  10.08660 1.000 30.91896 ? 58  VAL A CB  1 
ATOM   225  C CG1 . VAL A 1 31  ? -19.01095 -7.78562  9.31030  1.000 36.34311 ? 58  VAL A CG1 1 
ATOM   226  C CG2 . VAL A 1 31  ? -21.03163 -6.32136  9.33448  1.000 34.16054 ? 58  VAL A CG2 1 
ATOM   227  N N   . LEU A 1 32  ? -18.72935 -8.99503  12.43256 1.000 26.47442 ? 59  LEU A N   1 
ATOM   228  C CA  . LEU A 1 32  ? -17.64352 -9.53351  13.23586 1.000 28.12777 ? 59  LEU A CA  1 
ATOM   229  C C   . LEU A 1 32  ? -16.95162 -10.65268 12.48811 1.000 26.84298 ? 59  LEU A C   1 
ATOM   230  O O   . LEU A 1 32  ? -17.58958 -11.44247 11.77257 1.000 27.17177 ? 59  LEU A O   1 
ATOM   231  C CB  . LEU A 1 32  ? -18.11710 -10.08600 14.59195 1.000 26.57247 ? 59  LEU A CB  1 
ATOM   232  C CG  . LEU A 1 32  ? -18.83988 -9.08342  15.49579 1.000 27.13047 ? 59  LEU A CG  1 
ATOM   233  C CD1 . LEU A 1 32  ? -19.63087 -9.82363  16.55893 1.000 37.22895 ? 59  LEU A CD1 1 
ATOM   234  C CD2 . LEU A 1 32  ? -17.87181 -8.10696  16.13437 1.000 31.36809 ? 59  LEU A CD2 1 
ATOM   235  N N   . TYR A 1 33  ? -15.63587 -10.70644 12.67141 1.000 23.78754 ? 60  TYR A N   1 
ATOM   236  C CA  . TYR A 1 33  ? -14.82925 -11.79214 12.14112 1.000 21.92629 ? 60  TYR A CA  1 
ATOM   237  C C   . TYR A 1 33  ? -13.80749 -12.10336 13.21676 1.000 22.21528 ? 60  TYR A C   1 
ATOM   238  O O   . TYR A 1 33  ? -12.98195 -11.23931 13.53958 1.000 21.33547 ? 60  TYR A O   1 
ATOM   239  C CB  . TYR A 1 33  ? -14.13049 -11.42939 10.81794 1.000 21.53864 ? 60  TYR A CB  1 
ATOM   240  C CG  . TYR A 1 33  ? -13.42474 -12.63352 10.22566 1.000 20.56211 ? 60  TYR A CG  1 
ATOM   241  C CD1 . TYR A 1 33  ? -14.13139 -13.58963 9.49667  1.000 22.19574 ? 60  TYR A CD1 1 
ATOM   242  C CD2 . TYR A 1 33  ? -12.05851 -12.84291 10.44660 1.000 19.82443 ? 60  TYR A CD2 1 
ATOM   243  C CE1 . TYR A 1 33  ? -13.50281 -14.70590 8.99973  1.000 23.79230 ? 60  TYR A CE1 1 
ATOM   244  C CE2 . TYR A 1 33  ? -11.41164 -13.96300 9.93821  1.000 20.45951 ? 60  TYR A CE2 1 
ATOM   245  C CZ  . TYR A 1 33  ? -12.15283 -14.88763 9.20653  1.000 24.59903 ? 60  TYR A CZ  1 
ATOM   246  O OH  . TYR A 1 33  ? -11.55366 -15.98801 8.67976  1.000 25.02087 ? 60  TYR A OH  1 
ATOM   247  N N   . ARG A 1 34  ? -13.87667 -13.32487 13.77857 1.000 19.28106 ? 61  ARG A N   1 
ATOM   248  C CA  . ARG A 1 34  ? -13.09840 -13.66998 14.96824 1.000 20.38189 ? 61  ARG A CA  1 
ATOM   249  C C   . ARG A 1 34  ? -13.31286 -12.60931 16.05138 1.000 23.76563 ? 61  ARG A C   1 
ATOM   250  O O   . ARG A 1 34  ? -12.38888 -12.19456 16.76145 1.000 18.99710 ? 61  ARG A O   1 
ATOM   251  C CB  . ARG A 1 34  ? -11.61367 -13.87485 14.66111 1.000 18.57808 ? 61  ARG A CB  1 
ATOM   252  C CG  . ARG A 1 34  ? -11.32487 -14.97592 13.60329 1.000 19.99488 ? 61  ARG A CG  1 
ATOM   253  C CD  . ARG A 1 34  ? -9.82881  -15.29606 13.56422 1.000 18.77483 ? 61  ARG A CD  1 
ATOM   254  N NE  . ARG A 1 34  ? -9.49402  -16.23534 12.49908 1.000 19.58227 ? 61  ARG A NE  1 
ATOM   255  C CZ  . ARG A 1 34  ? -9.70224  -17.54537 12.53544 1.000 25.96565 ? 61  ARG A CZ  1 
ATOM   256  N NH1 . ARG A 1 34  ? -10.18343 -18.14431 13.62355 1.000 24.60958 ? 61  ARG A NH1 1 
ATOM   257  N NH2 . ARG A 1 34  ? -9.45117  -18.27381 11.43475 1.000 24.50965 ? 61  ARG A NH2 1 
ATOM   258  N N   . GLY A 1 35  ? -14.56588 -12.16548 16.16259 1.000 20.68288 ? 62  GLY A N   1 
ATOM   259  C CA  . GLY A 1 35  ? -14.90977 -11.05739 17.05468 1.000 22.07634 ? 62  GLY A CA  1 
ATOM   260  C C   . GLY A 1 35  ? -14.67495 -11.31691 18.52957 1.000 23.64799 ? 62  GLY A C   1 
ATOM   261  O O   . GLY A 1 35  ? -14.49879 -10.35752 19.28238 1.000 22.22501 ? 62  GLY A O   1 
ATOM   262  N N   . ASP A 1 36  ? -14.66837 -12.57978 18.95974 1.000 21.35084 ? 63  ASP A N   1 
ATOM   263  C CA  . ASP A 1 36  ? -14.49098 -12.89778 20.37287 1.000 19.59863 ? 63  ASP A CA  1 
ATOM   264  C C   . ASP A 1 36  ? -13.17539 -13.58626 20.66166 1.000 23.76875 ? 63  ASP A C   1 
ATOM   265  O O   . ASP A 1 36  ? -13.01393 -14.15107 21.74861 1.000 25.44073 ? 63  ASP A O   1 
ATOM   266  C CB  . ASP A 1 36  ? -15.64071 -13.77212 20.86443 1.000 22.78292 ? 63  ASP A CB  1 
ATOM   267  C CG  . ASP A 1 36  ? -16.95980 -13.04118 20.83299 1.000 31.15683 ? 63  ASP A CG  1 
ATOM   268  O OD1 . ASP A 1 36  ? -17.03797 -11.90205 21.35740 1.000 30.56446 ? 63  ASP A OD1 1 
ATOM   269  O OD2 . ASP A 1 36  ? -17.91682 -13.58740 20.25251 1.000 37.09743 ? 63  ASP A OD2 1 
ATOM   270  N N   . GLU A 1 37  ? -12.23689 -13.57165 19.73110 1.000 19.14513 ? 64  GLU A N   1 
ATOM   271  C CA  . GLU A 1 37  ? -10.90372 -14.06752 20.01654 1.000 17.20289 ? 64  GLU A CA  1 
ATOM   272  C C   . GLU A 1 37  ? -10.02189 -12.95739 20.56532 1.000 20.11679 ? 64  GLU A C   1 
ATOM   273  O O   . GLU A 1 37  ? -10.13129 -11.79930 20.16064 1.000 19.01452 ? 64  GLU A O   1 
ATOM   274  C CB  . GLU A 1 37  ? -10.24642 -14.63056 18.74396 1.000 18.15097 ? 64  GLU A CB  1 
ATOM   275  C CG  . GLU A 1 37  ? -10.98120 -15.86461 18.19259 1.000 19.52579 ? 64  GLU A CG  1 
ATOM   276  C CD  . GLU A 1 37  ? -10.25607 -16.55043 17.05031 1.000 18.73294 ? 64  GLU A CD  1 
ATOM   277  O OE1 . GLU A 1 37  ? -9.03285  -16.39822 16.94461 1.000 20.22668 ? 64  GLU A OE1 1 
ATOM   278  O OE2 . GLU A 1 37  ? -10.95138 -17.23537 16.27574 1.000 21.99180 ? 64  GLU A OE2 1 
ATOM   279  N N   . ARG A 1 38  ? -9.08525  -13.33378 21.43383 1.000 17.64561 ? 65  ARG A N   1 
ATOM   280  C CA  . ARG A 1 38  ? -8.12907  -12.35311 21.95529 1.000 16.27428 ? 65  ARG A CA  1 
ATOM   281  C C   . ARG A 1 38  ? -6.99688  -12.08763 20.97819 1.000 17.44250 ? 65  ARG A C   1 
ATOM   282  O O   . ARG A 1 38  ? -6.51528  -12.99683 20.29993 1.000 17.91792 ? 65  ARG A O   1 
ATOM   283  C CB  . ARG A 1 38  ? -7.55016  -12.84145 23.28497 1.000 17.64346 ? 65  ARG A CB  1 
ATOM   284  C CG  . ARG A 1 38  ? -8.60030  -12.70954 24.35841 1.000 24.77331 ? 65  ARG A CG  1 
ATOM   285  C CD  . ARG A 1 38  ? -8.04927  -12.80046 25.74760 1.000 27.51817 ? 65  ARG A CD  1 
ATOM   286  N NE  . ARG A 1 38  ? -9.08817  -12.50569 26.74075 1.000 31.67484 ? 65  ARG A NE  1 
ATOM   287  C CZ  . ARG A 1 38  ? -9.28320  -11.33028 27.33287 1.000 29.46789 ? 65  ARG A CZ  1 
ATOM   288  N NH1 . ARG A 1 38  ? -8.52172  -10.26969 27.05848 1.000 19.67353 ? 65  ARG A NH1 1 
ATOM   289  N NH2 . ARG A 1 38  ? -10.26726 -11.21377 28.22886 1.000 34.10920 ? 65  ARG A NH2 1 
ATOM   290  N N   . PHE A 1 39  ? -6.57661  -10.82492 20.89540 1.000 15.47200 ? 66  PHE A N   1 
ATOM   291  C CA  . PHE A 1 39  ? -5.45292  -10.38427 20.08167 1.000 14.81517 ? 66  PHE A CA  1 
ATOM   292  C C   . PHE A 1 39  ? -4.59676  -9.46262  20.93456 1.000 13.56712 ? 66  PHE A C   1 
ATOM   293  O O   . PHE A 1 39  ? -5.14213  -8.72917  21.78229 1.000 14.64751 ? 66  PHE A O   1 
ATOM   294  C CB  . PHE A 1 39  ? -5.90514  -9.57074  18.86343 1.000 15.13737 ? 66  PHE A CB  1 
ATOM   295  C CG  . PHE A 1 39  ? -6.56923  -10.36593 17.81348 1.000 12.72313 ? 66  PHE A CG  1 
ATOM   296  C CD1 . PHE A 1 39  ? -7.91107  -10.72480 17.95081 1.000 14.71882 ? 66  PHE A CD1 1 
ATOM   297  C CD2 . PHE A 1 39  ? -5.86256  -10.71008 16.66667 1.000 14.30343 ? 66  PHE A CD2 1 
ATOM   298  C CE1 . PHE A 1 39  ? -8.55760  -11.46691 16.91407 1.000 17.23995 ? 66  PHE A CE1 1 
ATOM   299  C CE2 . PHE A 1 39  ? -6.49541  -11.46072 15.64859 1.000 15.16060 ? 66  PHE A CE2 1 
ATOM   300  C CZ  . PHE A 1 39  ? -7.83929  -11.81620 15.79207 1.000 15.19826 ? 66  PHE A CZ  1 
ATOM   301  N N   . PRO A 1 40  ? -3.27932  -9.42514  20.70882 1.000 14.64463 ? 67  PRO A N   1 
ATOM   302  C CA  . PRO A 1 40  ? -2.43152  -8.44607  21.41787 1.000 14.67749 ? 67  PRO A CA  1 
ATOM   303  C C   . PRO A 1 40  ? -2.75555  -7.03386  20.95988 1.000 15.28501 ? 67  PRO A C   1 
ATOM   304  O O   . PRO A 1 40  ? -2.81866  -6.77444  19.75625 1.000 14.43960 ? 67  PRO A O   1 
ATOM   305  C CB  . PRO A 1 40  ? -0.98604  -8.81289  21.01098 1.000 17.58348 ? 67  PRO A CB  1 
ATOM   306  C CG  . PRO A 1 40  ? -1.06681  -10.08175 20.16961 1.000 19.59737 ? 67  PRO A CG  1 
ATOM   307  C CD  . PRO A 1 40  ? -2.53297  -10.32790 19.79787 1.000 16.19724 ? 67  PRO A CD  1 
ATOM   308  N N   . MET A 1 41  ? -2.99759  -6.13755  21.92604 1.000 12.85427 ? 68  MET A N   1 
ATOM   309  C CA  . MET A 1 41  ? -3.38640  -4.76077  21.60434 1.000 12.09056 ? 68  MET A CA  1 
ATOM   310  C C   . MET A 1 41  ? -2.24106  -3.94699  21.04337 1.000 14.64379 ? 68  MET A C   1 
ATOM   311  O O   . MET A 1 41  ? -2.46535  -3.05113  20.20288 1.000 15.40033 ? 68  MET A O   1 
ATOM   312  C CB  . MET A 1 41  ? -3.89658  -4.07301  22.86133 1.000 13.99005 ? 68  MET A CB  1 
ATOM   313  C CG  . MET A 1 41  ? -5.31298  -4.47803  23.12643 1.000 17.57296 ? 68  MET A CG  1 
ATOM   314  S SD  . MET A 1 41  ? -5.94792  -3.65221  24.59895 1.000 17.27355 ? 68  MET A SD  1 
ATOM   315  C CE  . MET A 1 41  ? -4.98319  -4.36262  25.94605 1.000 16.95038 ? 68  MET A CE  1 
ATOM   316  N N   . CYS A 1 42  ? -1.02704  -4.18596  21.55478 1.000 14.64201 ? 69  CYS A N   1 
ATOM   317  C CA  . CYS A 1 42  ? 0.09505   -3.28945  21.29470 1.000 12.55948 ? 69  CYS A CA  1 
ATOM   318  C C   . CYS A 1 42  ? -0.35102  -1.83637  21.49074 1.000 14.46451 ? 69  CYS A C   1 
ATOM   319  O O   . CYS A 1 42  ? -1.04820  -1.53490  22.47551 1.000 14.46563 ? 69  CYS A O   1 
ATOM   320  C CB  . CYS A 1 42  ? 0.68774   -3.57761  19.89037 1.000 14.95417 ? 69  CYS A CB  1 
ATOM   321  S SG  . CYS A 1 42  ? 1.24338   -5.29741  19.73989 1.000 18.48103 ? 69  CYS A SG  1 
ATOM   322  N N   . SER A 1 43  ? 0.07269   -0.89583  20.61886 1.000 13.01651 ? 70  SER A N   1 
ATOM   323  C CA  . SER A 1 43  ? -0.18800  0.51075   20.91474 1.000 14.47903 ? 70  SER A CA  1 
ATOM   324  C C   . SER A 1 43  ? -1.64330  0.91685   20.84114 1.000 14.68843 ? 70  SER A C   1 
ATOM   325  O O   . SER A 1 43  ? -1.93817  2.05227   21.21644 1.000 14.95979 ? 70  SER A O   1 
ATOM   326  C CB  . SER A 1 43  ? 0.59410   1.46894   19.99348 1.000 18.40150 ? 70  SER A CB  1 
ATOM   327  O OG  . SER A 1 43  ? 1.95191   1.46691   20.40949 1.000 24.37403 ? 70  SER A OG  1 
ATOM   328  N N   . THR A 1 44  ? -2.56575  0.05671   20.38185 1.000 12.94114 ? 71  THR A N   1 
ATOM   329  C CA  . THR A 1 44  ? -3.97299  0.45498   20.44153 1.000 12.66455 ? 71  THR A CA  1 
ATOM   330  C C   . THR A 1 44  ? -4.42974  0.63361   21.89722 1.000 13.72585 ? 71  THR A C   1 
ATOM   331  O O   . THR A 1 44  ? -5.39400  1.38016   22.14123 1.000 17.87606 ? 71  THR A O   1 
ATOM   332  C CB  . THR A 1 44  ? -4.89862  -0.52768  19.71090 1.000 14.12307 ? 71  THR A CB  1 
ATOM   333  O OG1 . THR A 1 44  ? -4.91572  -1.83109  20.34184 1.000 15.69141 ? 71  THR A OG1 1 
ATOM   334  C CG2 . THR A 1 44  ? -4.50302  -0.61037  18.22377 1.000 16.91998 ? 71  THR A CG2 1 
ATOM   335  N N   . SER A 1 45  ? -3.70112  0.06081   22.85678 1.000 14.69644 ? 72  SER A N   1 
ATOM   336  C CA  . SER A 1 45  ? -4.00870  0.24813   24.27854 1.000 12.78127 ? 72  SER A CA  1 
ATOM   337  C C   . SER A 1 45  ? -3.81001  1.68696   24.75328 1.000 14.28170 ? 72  SER A C   1 
ATOM   338  O O   . SER A 1 45  ? -4.36516  2.08829   25.79053 1.000 16.22082 ? 72  SER A O   1 
ATOM   339  C CB  . SER A 1 45  ? -3.12345  -0.68227  25.12048 1.000 12.63292 ? 72  SER A CB  1 
ATOM   340  O OG  . SER A 1 45  ? -1.75000  -0.38271  24.92324 1.000 18.94404 ? 72  SER A OG  1 
ATOM   341  N N   A LYS A 1 46  ? -3.07219  2.49814   23.99709 0.583 15.46160 ? 73  LYS A N   1 
ATOM   342  N N   B LYS A 1 46  ? -3.04923  2.48281   23.99909 0.417 15.45597 ? 73  LYS A N   1 
ATOM   343  C CA  A LYS A 1 46  ? -2.84626  3.88756   24.39891 0.583 15.63551 ? 73  LYS A CA  1 
ATOM   344  C CA  B LYS A 1 46  ? -2.83721  3.88207   24.36205 0.417 15.65597 ? 73  LYS A CA  1 
ATOM   345  C C   A LYS A 1 46  ? -4.13333  4.70229   24.41298 0.583 16.90226 ? 73  LYS A C   1 
ATOM   346  C C   B LYS A 1 46  ? -4.14522  4.65221   24.45600 0.417 16.86460 ? 73  LYS A C   1 
ATOM   347  O O   A LYS A 1 46  ? -4.22842  5.69751   25.14081 0.583 17.29599 ? 73  LYS A O   1 
ATOM   348  O O   B LYS A 1 46  ? -4.26774  5.55657   25.28995 0.417 17.06743 ? 73  LYS A O   1 
ATOM   349  C CB  A LYS A 1 46  ? -1.80106  4.51714   23.47698 0.583 16.80287 ? 73  LYS A CB  1 
ATOM   350  C CB  B LYS A 1 46  ? -1.89069  4.54331   23.35625 0.417 16.69379 ? 73  LYS A CB  1 
ATOM   351  C CG  A LYS A 1 46  ? -0.40642  3.89525   23.70324 0.583 17.06191 ? 73  LYS A CG  1 
ATOM   352  C CG  B LYS A 1 46  ? -0.43125  4.09329   23.53148 0.417 17.77213 ? 73  LYS A CG  1 
ATOM   353  C CD  A LYS A 1 46  ? 0.55690   4.17614   22.54228 0.583 17.44448 ? 73  LYS A CD  1 
ATOM   354  C CD  B LYS A 1 46  ? 0.50084   4.75581   22.50438 0.417 15.62873 ? 73  LYS A CD  1 
ATOM   355  C CE  A LYS A 1 46  ? 1.95219   3.71910   22.94113 0.583 15.21915 ? 73  LYS A CE  1 
ATOM   356  C CE  B LYS A 1 46  ? 1.94574   4.45234   22.83610 0.417 15.87625 ? 73  LYS A CE  1 
ATOM   357  N NZ  A LYS A 1 46  ? 2.93477   3.63705   21.82326 0.583 18.79206 ? 73  LYS A NZ  1 
ATOM   358  N NZ  B LYS A 1 46  ? 2.19799   2.99033   22.98246 0.417 16.90542 ? 73  LYS A NZ  1 
ATOM   359  N N   . VAL A 1 47  ? -5.13101  4.32517   23.61486 1.000 14.13822 ? 74  VAL A N   1 
ATOM   360  C CA  . VAL A 1 47  ? -6.40502  5.03694   23.68101 1.000 17.65958 ? 74  VAL A CA  1 
ATOM   361  C C   . VAL A 1 47  ? -7.01305  4.92758   25.06686 1.000 19.68818 ? 74  VAL A C   1 
ATOM   362  O O   . VAL A 1 47  ? -7.55939  5.89982   25.59969 1.000 18.63983 ? 74  VAL A O   1 
ATOM   363  C CB  . VAL A 1 47  ? -7.39183  4.50951   22.62868 1.000 18.49667 ? 74  VAL A CB  1 
ATOM   364  C CG1 . VAL A 1 47  ? -8.74962  5.19159   22.77510 1.000 25.77069 ? 74  VAL A CG1 1 
ATOM   365  C CG2 . VAL A 1 47  ? -6.82292  4.71572   21.17902 1.000 23.94534 ? 74  VAL A CG2 1 
ATOM   366  N N   A MET A 1 48  ? -6.95360  3.73459   25.66601 0.688 17.66879 ? 75  MET A N   1 
ATOM   367  N N   B MET A 1 48  ? -6.93397  3.74693   25.67868 0.312 17.65372 ? 75  MET A N   1 
ATOM   368  C CA  A MET A 1 48  ? -7.55723  3.54195   26.98514 0.688 16.83601 ? 75  MET A CA  1 
ATOM   369  C CA  B MET A 1 48  ? -7.55794  3.56849   26.98651 0.312 16.85824 ? 75  MET A CA  1 
ATOM   370  C C   A MET A 1 48  ? -6.82341  4.34584   28.05487 0.688 17.38502 ? 75  MET A C   1 
ATOM   371  C C   B MET A 1 48  ? -6.81660  4.33795   28.07058 0.312 17.40901 ? 75  MET A C   1 
ATOM   372  O O   A MET A 1 48  ? -7.45361  4.91240   28.95863 0.688 18.48931 ? 75  MET A O   1 
ATOM   373  O O   B MET A 1 48  ? -7.43876  4.87226   28.99749 0.312 18.48438 ? 75  MET A O   1 
ATOM   374  C CB  A MET A 1 48  ? -7.57269  2.04645   27.33148 0.688 17.25321 ? 75  MET A CB  1 
ATOM   375  C CB  B MET A 1 48  ? -7.62985  2.08324   27.32426 0.312 17.32281 ? 75  MET A CB  1 
ATOM   376  C CG  A MET A 1 48  ? -8.48534  1.63934   28.48488 0.688 17.94818 ? 75  MET A CG  1 
ATOM   377  C CG  B MET A 1 48  ? -8.61505  1.34893   26.45629 0.312 21.47989 ? 75  MET A CG  1 
ATOM   378  S SD  A MET A 1 48  ? -10.27052 1.76762   28.08509 0.688 22.14384 ? 75  MET A SD  1 
ATOM   379  S SD  B MET A 1 48  ? -10.28313 1.91696   26.80686 0.312 20.57209 ? 75  MET A SD  1 
ATOM   380  C CE  A MET A 1 48  ? -10.55886 0.17305   27.35356 0.688 21.07367 ? 75  MET A CE  1 
ATOM   381  C CE  B MET A 1 48  ? -10.38755 1.60361   28.56097 0.312 21.14683 ? 75  MET A CE  1 
ATOM   382  N N   . ALA A 1 49  ? -5.48638  4.39899   27.98356 1.000 16.72231 ? 76  ALA A N   1 
ATOM   383  C CA  . ALA A 1 49  ? -4.73558  5.16360   28.97678 1.000 16.09774 ? 76  ALA A CA  1 
ATOM   384  C C   . ALA A 1 49  ? -5.05504  6.65006   28.85494 1.000 19.32620 ? 76  ALA A C   1 
ATOM   385  O O   . ALA A 1 49  ? -5.29526  7.32588   29.85425 1.000 20.37489 ? 76  ALA A O   1 
ATOM   386  C CB  . ALA A 1 49  ? -3.23318  4.91269   28.81007 1.000 19.80089 ? 76  ALA A CB  1 
ATOM   387  N N   . ALA A 1 50  ? -5.09025  7.17914   27.63663 1.000 17.03425 ? 77  ALA A N   1 
ATOM   388  C CA  . ALA A 1 50  ? -5.43254  8.58303   27.46930 1.000 18.08637 ? 77  ALA A CA  1 
ATOM   389  C C   . ALA A 1 50  ? -6.85900  8.87599   27.93574 1.000 19.46090 ? 77  ALA A C   1 
ATOM   390  O O   . ALA A 1 50  ? -7.11969  9.90751   28.56174 1.000 21.13051 ? 77  ALA A O   1 
ATOM   391  C CB  . ALA A 1 50  ? -5.25135  8.98295   25.99803 1.000 19.52318 ? 77  ALA A CB  1 
ATOM   392  N N   . ALA A 1 51  ? -7.80705  7.99643   27.61137 1.000 19.20595 ? 78  ALA A N   1 
ATOM   393  C CA  . ALA A 1 51  ? -9.17967  8.22863   28.04566 1.000 18.75822 ? 78  ALA A CA  1 
ATOM   394  C C   . ALA A 1 51  ? -9.28426  8.17013   29.56024 1.000 20.67522 ? 78  ALA A C   1 
ATOM   395  O O   . ALA A 1 51  ? -10.09913 8.87722   30.15799 1.000 20.93331 ? 78  ALA A O   1 
ATOM   396  C CB  . ALA A 1 51  ? -10.12545 7.19688   27.40090 1.000 20.78499 ? 78  ALA A CB  1 
ATOM   397  N N   . ALA A 1 52  ? -8.47771  7.32088   30.19480 1.000 17.28708 ? 79  ALA A N   1 
ATOM   398  C CA  . ALA A 1 52  ? -8.54749  7.26457   31.66047 1.000 17.74774 ? 79  ALA A CA  1 
ATOM   399  C C   . ALA A 1 52  ? -8.09673  8.58139   32.27632 1.000 22.31776 ? 79  ALA A C   1 
ATOM   400  O O   . ALA A 1 52  ? -8.62951  9.02511   33.30824 1.000 22.00346 ? 79  ALA A O   1 
ATOM   401  C CB  . ALA A 1 52  ? -7.67440  6.12502   32.18309 1.000 18.28878 ? 79  ALA A CB  1 
ATOM   402  N N   . VAL A 1 53  ? -7.05601  9.18593   31.70792 1.000 19.27823 ? 80  VAL A N   1 
ATOM   403  C CA  . VAL A 1 53  ? -6.59782  10.46124  32.26420 1.000 19.31837 ? 80  VAL A CA  1 
ATOM   404  C C   . VAL A 1 53  ? -7.62144  11.53829  31.97574 1.000 23.94471 ? 80  VAL A C   1 
ATOM   405  O O   . VAL A 1 53  ? -7.87623  12.41373  32.81584 1.000 20.75950 ? 80  VAL A O   1 
ATOM   406  C CB  . VAL A 1 53  ? -5.20139  10.78741  31.69804 1.000 22.39581 ? 80  VAL A CB  1 
ATOM   407  C CG1 . VAL A 1 53  ? -4.76812  12.22414  32.07192 1.000 27.30370 ? 80  VAL A CG1 1 
ATOM   408  C CG2 . VAL A 1 53  ? -4.20804  9.75550   32.17664 1.000 22.83965 ? 80  VAL A CG2 1 
ATOM   409  N N   . LEU A 1 54  ? -8.26988  11.45327  30.80608 1.000 21.29169 ? 81  LEU A N   1 
ATOM   410  C CA  . LEU A 1 54  ? -9.34397  12.40358  30.49451 1.000 24.66988 ? 81  LEU A CA  1 
ATOM   411  C C   . LEU A 1 54  ? -10.47724 12.28489  31.50890 1.000 22.30871 ? 81  LEU A C   1 
ATOM   412  O O   . LEU A 1 54  ? -11.02235 13.29729  31.96773 1.000 23.96433 ? 81  LEU A O   1 
ATOM   413  C CB  . LEU A 1 54  ? -9.87151  12.19007  29.06729 1.000 21.25140 ? 81  LEU A CB  1 
ATOM   414  C CG  . LEU A 1 54  ? -9.00802  12.71017  27.93026 1.000 22.80137 ? 81  LEU A CG  1 
ATOM   415  C CD1 . LEU A 1 54  ? -9.61276  12.29189  26.58296 1.000 23.30584 ? 81  LEU A CD1 1 
ATOM   416  C CD2 . LEU A 1 54  ? -8.89111  14.24442  28.03535 1.000 27.14694 ? 81  LEU A CD2 1 
ATOM   417  N N   . LYS A 1 55  ? -10.81244 11.05658  31.91331 1.000 21.59321 ? 82  LYS A N   1 
ATOM   418  C CA  . LYS A 1 55  ? -11.86890 10.87584  32.90890 1.000 23.08772 ? 82  LYS A CA  1 
ATOM   419  C C   . LYS A 1 55  ? -11.47237 11.49620  34.24507 1.000 26.10138 ? 82  LYS A C   1 
ATOM   420  O O   . LYS A 1 55  ? -12.30067 12.12144  34.92837 1.000 26.87635 ? 82  LYS A O   1 
ATOM   421  C CB  . LYS A 1 55  ? -12.18654 9.38297   33.06240 1.000 23.78600 ? 82  LYS A CB  1 
ATOM   422  C CG  . LYS A 1 55  ? -13.09673 9.05057   34.22672 1.000 26.26703 ? 82  LYS A CG  1 
ATOM   423  C CD  . LYS A 1 55  ? -14.45531 9.73914   34.20860 1.000 33.94527 ? 82  LYS A CD  1 
ATOM   424  C CE  . LYS A 1 55  ? -15.33420 9.20395   33.07061 1.000 31.68529 ? 82  LYS A CE  1 
ATOM   425  N NZ  . LYS A 1 55  ? -16.71254 9.87073   33.08612 1.000 33.38142 ? 82  LYS A NZ  1 
ATOM   426  N N   . GLN A 1 56  ? -10.19638 11.39459  34.61265 1.000 22.11748 ? 83  GLN A N   1 
ATOM   427  C CA  . GLN A 1 56  ? -9.75477  12.02255  35.85881 1.000 25.58634 ? 83  GLN A CA  1 
ATOM   428  C C   . GLN A 1 56  ? -9.86660  13.53658  35.80873 1.000 32.66958 ? 83  GLN A C   1 
ATOM   429  O O   . GLN A 1 56  ? -10.11104 14.18482  36.84142 1.000 28.60867 ? 83  GLN A O   1 
ATOM   430  C CB  . GLN A 1 56  ? -8.30661  11.63466  36.15848 1.000 24.46369 ? 83  GLN A CB  1 
ATOM   431  C CG  . GLN A 1 56  ? -8.09714  10.21694  36.61469 1.000 27.00776 ? 83  GLN A CG  1 
ATOM   432  C CD  . GLN A 1 56  ? -6.63859  9.98779   36.95403 1.000 38.90316 ? 83  GLN A CD  1 
ATOM   433  O OE1 . GLN A 1 56  ? -5.74946  10.52507  36.27976 1.000 33.57958 ? 83  GLN A OE1 1 
ATOM   434  N NE2 . GLN A 1 56  ? -6.37692  9.20149   37.99603 1.000 40.18719 ? 83  GLN A NE2 1 
ATOM   435  N N   . SER A 1 57  ? -9.67336  14.12052  34.63364 1.000 28.61792 ? 84  SER A N   1 
ATOM   436  C CA  . SER A 1 57  ? -9.72305  15.56320  34.46062 1.000 26.12546 ? 84  SER A CA  1 
ATOM   437  C C   . SER A 1 57  ? -11.13065 16.12253  34.59678 1.000 30.58953 ? 84  SER A C   1 
ATOM   438  O O   . SER A 1 57  ? -11.28699 17.35518  34.65712 1.000 32.35642 ? 84  SER A O   1 
ATOM   439  C CB  . SER A 1 57  ? -9.13731  15.93537  33.07749 1.000 23.96100 ? 84  SER A CB  1 
ATOM   440  O OG  . SER A 1 57  ? -10.07427 15.73561  32.03173 1.000 27.87168 ? 84  SER A OG  1 
ATOM   441  N N   . GLU A 1 58  ? -12.15805 15.26104  34.65499 1.000 26.68344 ? 85  GLU A N   1 
ATOM   442  C CA  . GLU A 1 58  ? -13.50710 15.78804  34.86852 1.000 29.55831 ? 85  GLU A CA  1 
ATOM   443  C C   . GLU A 1 58  ? -13.68266 16.31540  36.28149 1.000 33.80560 ? 85  GLU A C   1 
ATOM   444  O O   . GLU A 1 58  ? -14.49040 17.21851  36.49706 1.000 35.59303 ? 85  GLU A O   1 
ATOM   445  C CB  . GLU A 1 58  ? -14.56776 14.72090  34.58750 1.000 27.04474 ? 85  GLU A CB  1 
ATOM   446  C CG  . GLU A 1 58  ? -14.57760 14.26205  33.11726 1.000 30.93666 ? 85  GLU A CG  1 
ATOM   447  C CD  . GLU A 1 58  ? -15.52018 13.10585  32.85832 1.000 27.94927 ? 85  GLU A CD  1 
ATOM   448  O OE1 . GLU A 1 58  ? -16.43012 12.86620  33.67599 1.000 38.31098 ? 85  GLU A OE1 1 
ATOM   449  O OE2 . GLU A 1 58  ? -15.32284 12.44046  31.81570 1.000 35.50602 ? 85  GLU A OE2 1 
ATOM   450  N N   . THR A 1 59  ? -12.98228 15.72957  37.25112 1.000 38.36062 ? 86  THR A N   1 
ATOM   451  C CA  . THR A 1 59  ? -12.96475 16.19644  38.63772 1.000 39.15185 ? 86  THR A CA  1 
ATOM   452  C C   . THR A 1 59  ? -11.78244 17.11703  38.91434 1.000 38.61214 ? 86  THR A C   1 
ATOM   453  O O   . THR A 1 59  ? -11.93805 18.13349  39.60017 1.000 45.76269 ? 86  THR A O   1 
ATOM   454  C CB  . THR A 1 59  ? -12.92720 14.98773  39.58388 1.000 41.75609 ? 86  THR A CB  1 
ATOM   455  O OG1 . THR A 1 59  ? -14.02227 14.11661  39.27856 1.000 45.51082 ? 86  THR A OG1 1 
ATOM   456  C CG2 . THR A 1 59  ? -13.04327 15.42398  41.05923 1.000 42.86367 ? 86  THR A CG2 1 
ATOM   457  N N   . GLN A 1 60  ? -10.60277 16.78354  38.39839 1.000 36.76382 ? 87  GLN A N   1 
ATOM   458  C CA  . GLN A 1 60  ? -9.39975  17.60777  38.53059 1.000 36.54338 ? 87  GLN A CA  1 
ATOM   459  C C   . GLN A 1 60  ? -9.27103  18.50550  37.30707 1.000 39.79505 ? 87  GLN A C   1 
ATOM   460  O O   . GLN A 1 60  ? -8.57809  18.18415  36.34569 1.000 35.54956 ? 87  GLN A O   1 
ATOM   461  C CB  . GLN A 1 60  ? -8.17979  16.71795  38.68767 1.000 34.72015 ? 87  GLN A CB  1 
ATOM   462  C CG  . GLN A 1 60  ? -8.28487  15.77459  39.86217 1.000 42.44782 ? 87  GLN A CG  1 
ATOM   463  C CD  . GLN A 1 60  ? -7.11963  14.79620  39.89594 1.000 44.66037 ? 87  GLN A CD  1 
ATOM   464  O OE1 . GLN A 1 60  ? -5.95936  15.20599  39.96224 1.000 54.61960 ? 87  GLN A OE1 1 
ATOM   465  N NE2 . GLN A 1 60  ? -7.42177  13.50440  39.82836 1.000 45.78414 ? 87  GLN A NE2 1 
ATOM   466  N N   . LYS A 1 61  ? -9.91067  19.66872  37.36335 1.000 39.80269 ? 88  LYS A N   1 
ATOM   467  C CA  . LYS A 1 61  ? -10.14226 20.44217  36.14767 1.000 41.77773 ? 88  LYS A CA  1 
ATOM   468  C C   . LYS A 1 61  ? -8.85390  20.90993  35.48904 1.000 39.49219 ? 88  LYS A C   1 
ATOM   469  O O   . LYS A 1 61  ? -8.82564  21.11362  34.27445 1.000 42.37673 ? 88  LYS A O   1 
ATOM   470  C CB  . LYS A 1 61  ? -11.03764 21.63041  36.46768 1.000 45.85309 ? 88  LYS A CB  1 
ATOM   471  C CG  . LYS A 1 61  ? -12.39607 21.19863  36.96319 1.000 51.36779 ? 88  LYS A CG  1 
ATOM   472  C CD  . LYS A 1 61  ? -13.16202 20.49639  35.86507 1.000 62.03903 ? 88  LYS A CD  1 
ATOM   473  C CE  . LYS A 1 61  ? -14.64826 20.76294  36.00890 1.000 67.24988 ? 88  LYS A CE  1 
ATOM   474  N NZ  . LYS A 1 61  ? -15.13006 20.29021  37.33837 1.000 70.42817 ? 88  LYS A NZ  1 
ATOM   475  N N   . GLN A 1 62  ? -7.78365  21.07434  36.25647 1.000 41.69891 ? 89  GLN A N   1 
ATOM   476  C CA  . GLN A 1 62  ? -6.51229  21.53588  35.72343 1.000 47.96972 ? 89  GLN A CA  1 
ATOM   477  C C   . GLN A 1 62  ? -5.55725  20.39390  35.39641 1.000 47.03141 ? 89  GLN A C   1 
ATOM   478  O O   . GLN A 1 62  ? -4.39636  20.65520  35.07468 1.000 39.84654 ? 89  GLN A O   1 
ATOM   479  C CB  . GLN A 1 62  ? -5.83427  22.48794  36.71494 1.000 58.59199 ? 89  GLN A CB  1 
ATOM   480  C CG  . GLN A 1 62  ? -6.70787  23.64094  37.17512 1.000 72.27809 ? 89  GLN A CG  1 
ATOM   481  C CD  . GLN A 1 62  ? -7.22913  24.44513  36.00964 1.000 82.45588 ? 89  GLN A CD  1 
ATOM   482  O OE1 . GLN A 1 62  ? -6.56142  24.57033  34.97972 1.000 84.07305 ? 89  GLN A OE1 1 
ATOM   483  N NE2 . GLN A 1 62  ? -8.43423  24.98668  36.15483 1.000 90.03854 ? 89  GLN A NE2 1 
ATOM   484  N N   . LEU A 1 63  ? -6.00363  19.13885  35.48680 1.000 38.54166 ? 90  LEU A N   1 
ATOM   485  C CA  . LEU A 1 63  ? -5.05230  18.02946  35.42360 1.000 33.95288 ? 90  LEU A CA  1 
ATOM   486  C C   . LEU A 1 63  ? -4.27908  18.02612  34.11092 1.000 35.03535 ? 90  LEU A C   1 
ATOM   487  O O   . LEU A 1 63  ? -3.07396  17.73452  34.08968 1.000 30.87263 ? 90  LEU A O   1 
ATOM   488  C CB  . LEU A 1 63  ? -5.77811  16.70328  35.60422 1.000 31.39357 ? 90  LEU A CB  1 
ATOM   489  C CG  . LEU A 1 63  ? -4.88962  15.44927  35.54637 1.000 33.54026 ? 90  LEU A CG  1 
ATOM   490  C CD1 . LEU A 1 63  ? -3.81247  15.49160  36.62710 1.000 30.42175 ? 90  LEU A CD1 1 
ATOM   491  C CD2 . LEU A 1 63  ? -5.78256  14.25031  35.70091 1.000 32.98444 ? 90  LEU A CD2 1 
ATOM   492  N N   . LEU A 1 64  ? -4.94879  18.33580  33.00653 1.000 32.13213 ? 91  LEU A N   1 
ATOM   493  C CA  . LEU A 1 64  ? -4.25439  18.20047  31.72443 1.000 31.26653 ? 91  LEU A CA  1 
ATOM   494  C C   . LEU A 1 64  ? -3.10337  19.19332  31.60236 1.000 36.70665 ? 91  LEU A C   1 
ATOM   495  O O   . LEU A 1 64  ? -2.20197  18.98344  30.79093 1.000 32.57393 ? 91  LEU A O   1 
ATOM   496  C CB  . LEU A 1 64  ? -5.22560  18.34994  30.55566 1.000 36.37961 ? 91  LEU A CB  1 
ATOM   497  C CG  . LEU A 1 64  ? -6.24286  17.21888  30.36502 1.000 34.72974 ? 91  LEU A CG  1 
ATOM   498  C CD1 . LEU A 1 64  ? -6.93927  17.35734  29.01223 1.000 38.24971 ? 91  LEU A CD1 1 
ATOM   499  C CD2 . LEU A 1 64  ? -5.59324  15.85501  30.46906 1.000 37.02394 ? 91  LEU A CD2 1 
ATOM   500  N N   . ASN A 1 65  ? -3.08466  20.26272  32.40973 1.000 34.29341 ? 92  ASN A N   1 
ATOM   501  C CA  . ASN A 1 65  ? -1.99895  21.22421  32.30413 1.000 35.80535 ? 92  ASN A CA  1 
ATOM   502  C C   . ASN A 1 65  ? -0.85624  20.92763  33.25830 1.000 35.46547 ? 92  ASN A C   1 
ATOM   503  O O   . ASN A 1 65  ? 0.10423   21.70267  33.31202 1.000 38.35111 ? 92  ASN A O   1 
ATOM   504  C CB  . ASN A 1 65  ? -2.52742  22.63348  32.55098 1.000 38.84206 ? 92  ASN A CB  1 
ATOM   505  C CG  . ASN A 1 65  ? -3.53334  23.03730  31.52197 1.000 51.79226 ? 92  ASN A CG  1 
ATOM   506  O OD1 . ASN A 1 65  ? -4.68028  23.34882  31.84808 1.000 69.68168 ? 92  ASN A OD1 1 
ATOM   507  N ND2 . ASN A 1 65  ? -3.12210  23.00414  30.25014 1.000 49.42227 ? 92  ASN A ND2 1 
ATOM   508  N N   . GLN A 1 66  ? -0.91676  19.81673  33.97055 1.000 34.88912 ? 93  GLN A N   1 
ATOM   509  C CA  . GLN A 1 66  ? 0.08475   19.52513  34.98251 1.000 35.10489 ? 93  GLN A CA  1 
ATOM   510  C C   . GLN A 1 66  ? 1.39951   19.14973  34.30788 1.000 37.97545 ? 93  GLN A C   1 
ATOM   511  O O   . GLN A 1 66  ? 1.40971   18.27655  33.42953 1.000 33.61287 ? 93  GLN A O   1 
ATOM   512  C CB  . GLN A 1 66  ? -0.41894  18.39619  35.87133 1.000 37.54981 ? 93  GLN A CB  1 
ATOM   513  C CG  . GLN A 1 66  ? 0.51472   17.99050  37.00458 1.000 55.33167 ? 93  GLN A CG  1 
ATOM   514  C CD  . GLN A 1 66  ? 0.06949   16.69097  37.66323 1.000 58.20194 ? 93  GLN A CD  1 
ATOM   515  O OE1 . GLN A 1 66  ? -0.94586  16.65435  38.36542 1.000 57.28955 ? 93  GLN A OE1 1 
ATOM   516  N NE2 . GLN A 1 66  ? 0.81607   15.61184  37.41890 1.000 53.24618 ? 93  GLN A NE2 1 
ATOM   517  N N   . PRO A 1 67  ? 2.51360   19.78482  34.67133 1.000 34.95798 ? 94  PRO A N   1 
ATOM   518  C CA  . PRO A 1 67  ? 3.80322   19.44398  34.05549 1.000 34.52195 ? 94  PRO A CA  1 
ATOM   519  C C   . PRO A 1 67  ? 4.34532   18.14967  34.63419 1.000 33.03479 ? 94  PRO A C   1 
ATOM   520  O O   . PRO A 1 67  ? 4.24666   17.89152  35.83651 1.000 33.70080 ? 94  PRO A O   1 
ATOM   521  C CB  . PRO A 1 67  ? 4.70918   20.63062  34.42353 1.000 39.26778 ? 94  PRO A CB  1 
ATOM   522  C CG  . PRO A 1 67  ? 3.82946   21.61920  35.16799 1.000 48.49102 ? 94  PRO A CG  1 
ATOM   523  C CD  . PRO A 1 67  ? 2.63443   20.87217  35.65493 1.000 37.90553 ? 94  PRO A CD  1 
ATOM   524  N N   . VAL A 1 68  ? 4.93578   17.34237  33.76555 1.000 31.28699 ? 95  VAL A N   1 
ATOM   525  C CA  . VAL A 1 68  ? 5.52358   16.06336  34.12928 1.000 30.02371 ? 95  VAL A CA  1 
ATOM   526  C C   . VAL A 1 68  ? 6.94457   16.04691  33.59035 1.000 30.55805 ? 95  VAL A C   1 
ATOM   527  O O   . VAL A 1 68  ? 7.14922   16.28368  32.39942 1.000 31.76369 ? 95  VAL A O   1 
ATOM   528  C CB  . VAL A 1 68  ? 4.71278   14.90082  33.52617 1.000 32.56298 ? 95  VAL A CB  1 
ATOM   529  C CG1 . VAL A 1 68  ? 5.42071   13.55068  33.78384 1.000 31.79446 ? 95  VAL A CG1 1 
ATOM   530  C CG2 . VAL A 1 68  ? 3.30061   14.90809  34.09143 1.000 35.34708 ? 95  VAL A CG2 1 
ATOM   531  N N   A GLU A 1 69  ? 7.91079   15.71487  34.44604 0.601 32.01340 ? 96  GLU A N   1 
ATOM   532  N N   B GLU A 1 69  ? 7.91441   15.77324  34.46493 0.399 32.04282 ? 96  GLU A N   1 
ATOM   533  C CA  A GLU A 1 69  ? 9.32536   15.77157  34.08896 0.601 33.06070 ? 96  GLU A CA  1 
ATOM   534  C CA  B GLU A 1 69  ? 9.30839   15.72953  34.04738 0.399 32.92595 ? 96  GLU A CA  1 
ATOM   535  C C   A GLU A 1 69  ? 9.71483   14.57741  33.22357 0.601 31.62894 ? 96  GLU A C   1 
ATOM   536  C C   B GLU A 1 69  ? 9.54087   14.59610  33.07027 0.399 32.28076 ? 96  GLU A C   1 
ATOM   537  O O   A GLU A 1 69  ? 9.33365   13.44482  33.51924 0.601 29.08580 ? 96  GLU A O   1 
ATOM   538  O O   B GLU A 1 69  ? 8.93185   13.52720  33.16518 0.399 30.18392 ? 96  GLU A O   1 
ATOM   539  C CB  A GLU A 1 69  ? 10.16246  15.79950  35.37434 0.601 35.78657 ? 96  GLU A CB  1 
ATOM   540  C CB  B GLU A 1 69  ? 10.23733  15.51150  35.23760 0.399 36.15107 ? 96  GLU A CB  1 
ATOM   541  C CG  A GLU A 1 69  ? 11.57782  16.32494  35.22618 0.601 38.44821 ? 96  GLU A CG  1 
ATOM   542  C CG  B GLU A 1 69  ? 10.08048  16.46252  36.36084 0.399 38.10668 ? 96  GLU A CG  1 
ATOM   543  C CD  A GLU A 1 69  ? 12.29854  16.36206  36.55583 0.601 42.81504 ? 96  GLU A CD  1 
ATOM   544  C CD  B GLU A 1 69  ? 10.85804  15.99531  37.56172 0.399 40.32723 ? 96  GLU A CD  1 
ATOM   545  O OE1 A GLU A 1 69  ? 11.70684  15.90607  37.55575 0.601 43.89103 ? 96  GLU A OE1 1 
ATOM   546  O OE1 B GLU A 1 69  ? 12.09778  16.14956  37.55713 0.399 42.57761 ? 96  GLU A OE1 1 
ATOM   547  O OE2 A GLU A 1 69  ? 13.44549  16.84217  36.59623 0.601 44.55499 ? 96  GLU A OE2 1 
ATOM   548  O OE2 B GLU A 1 69  ? 10.23826  15.43625  38.48386 0.399 40.04997 ? 96  GLU A OE2 1 
ATOM   549  N N   . ILE A 1 70  ? 10.46618  14.82305  32.14617 1.000 30.69340 ? 97  ILE A N   1 
ATOM   550  C CA  . ILE A 1 70  ? 10.98122  13.75713  31.28110 1.000 28.77876 ? 97  ILE A CA  1 
ATOM   551  C C   . ILE A 1 70  ? 12.46394  13.62085  31.59277 1.000 35.33260 ? 97  ILE A C   1 
ATOM   552  O O   . ILE A 1 70  ? 13.24226  14.54334  31.33071 1.000 34.93066 ? 97  ILE A O   1 
ATOM   553  C CB  . ILE A 1 70  ? 10.76590  14.04851  29.78700 1.000 30.30095 ? 97  ILE A CB  1 
ATOM   554  C CG1 . ILE A 1 70  ? 9.30589   14.41465  29.53126 1.000 30.17841 ? 97  ILE A CG1 1 
ATOM   555  C CG2 . ILE A 1 70  ? 11.19198  12.85100  28.98118 1.000 32.91548 ? 97  ILE A CG2 1 
ATOM   556  C CD1 . ILE A 1 70  ? 8.34860   13.28833  29.74896 1.000 31.37198 ? 97  ILE A CD1 1 
ATOM   557  N N   . LYS A 1 71  ? 12.85387  12.49869  32.18219 1.000 31.38684 ? 98  LYS A N   1 
ATOM   558  C CA  . LYS A 1 71  ? 14.24598  12.27660  32.54947 1.000 33.40319 ? 98  LYS A CA  1 
ATOM   559  C C   . LYS A 1 71  ? 14.87834  11.27265  31.58944 1.000 31.16016 ? 98  LYS A C   1 
ATOM   560  O O   . LYS A 1 71  ? 14.16576  10.47998  30.96025 1.000 31.83355 ? 98  LYS A O   1 
ATOM   561  C CB  . LYS A 1 71  ? 14.35322  11.76926  34.00005 1.000 35.56725 ? 98  LYS A CB  1 
ATOM   562  C CG  . LYS A 1 71  ? 13.95011  12.81520  35.05948 1.000 45.18627 ? 98  LYS A CG  1 
ATOM   563  C CD  . LYS A 1 71  ? 13.89417  12.23414  36.48572 1.000 63.70682 ? 98  LYS A CD  1 
ATOM   564  C CE  . LYS A 1 71  ? 12.98612  10.98972  36.57985 1.000 72.24831 ? 98  LYS A CE  1 
ATOM   565  N NZ  . LYS A 1 71  ? 11.57374  11.18200  36.09340 1.000 58.68314 ? 98  LYS A NZ  1 
ATOM   566  N N   . PRO A 1 72  ? 16.21724  11.27268  31.44385 1.000 33.15649 ? 99  PRO A N   1 
ATOM   567  C CA  . PRO A 1 72  ? 16.84316  10.29983  30.52047 1.000 34.59604 ? 99  PRO A CA  1 
ATOM   568  C C   . PRO A 1 72  ? 16.45921  8.86063   30.80994 1.000 40.05923 ? 99  PRO A C   1 
ATOM   569  O O   . PRO A 1 72  ? 16.31643  8.05695   29.87358 1.000 41.13319 ? 99  PRO A O   1 
ATOM   570  C CB  . PRO A 1 72  ? 18.34728  10.53567  30.71435 1.000 35.61301 ? 99  PRO A CB  1 
ATOM   571  C CG  . PRO A 1 72  ? 18.43801  11.95916  31.15018 1.000 39.83623 ? 99  PRO A CG  1 
ATOM   572  C CD  . PRO A 1 72  ? 17.20319  12.22129  32.00099 1.000 37.02886 ? 99  PRO A CD  1 
ATOM   573  N N   . ALA A 1 73  ? 16.25716  8.52490   32.08591 1.000 32.88348 ? 100 ALA A N   1 
ATOM   574  C CA  . ALA A 1 73  ? 15.89744  7.17447   32.51161 1.000 40.03350 ? 100 ALA A CA  1 
ATOM   575  C C   . ALA A 1 73  ? 14.47245  6.79795   32.13364 1.000 37.26593 ? 100 ALA A C   1 
ATOM   576  O O   . ALA A 1 73  ? 14.12612  5.61597   32.20385 1.000 41.74849 ? 100 ALA A O   1 
ATOM   577  C CB  . ALA A 1 73  ? 16.07829  7.03240   34.01957 1.000 40.37016 ? 100 ALA A CB  1 
ATOM   578  N N   . ASP A 1 74  ? 13.63828  7.77096   31.75690 1.000 32.94277 ? 101 ASP A N   1 
ATOM   579  C CA  . ASP A 1 74  ? 12.26715  7.49133   31.33655 1.000 33.32346 ? 101 ASP A CA  1 
ATOM   580  C C   . ASP A 1 74  ? 12.18540  6.99154   29.90858 1.000 37.44042 ? 101 ASP A C   1 
ATOM   581  O O   . ASP A 1 74  ? 11.19321  6.35917   29.53322 1.000 33.45877 ? 101 ASP A O   1 
ATOM   582  C CB  . ASP A 1 74  ? 11.40553  8.75253   31.42986 1.000 33.12989 ? 101 ASP A CB  1 
ATOM   583  C CG  . ASP A 1 74  ? 11.20383  9.21534   32.85861 1.000 39.95373 ? 101 ASP A CG  1 
ATOM   584  O OD1 . ASP A 1 74  ? 11.09652  8.35193   33.76149 1.000 38.86403 ? 101 ASP A OD1 1 
ATOM   585  O OD2 . ASP A 1 74  ? 11.14984  10.44837  33.07244 1.000 34.92586 ? 101 ASP A OD2 1 
ATOM   586  N N   . LEU A 1 75  ? 13.18573  7.29517   29.10007 1.000 31.79626 ? 102 LEU A N   1 
ATOM   587  C CA  . LEU A 1 75  ? 13.11486  6.99301   27.68205 1.000 31.86067 ? 102 LEU A CA  1 
ATOM   588  C C   . LEU A 1 75  ? 13.20533  5.49456   27.45930 1.000 36.38782 ? 102 LEU A C   1 
ATOM   589  O O   . LEU A 1 75  ? 14.02742  4.81229   28.07921 1.000 36.48502 ? 102 LEU A O   1 
ATOM   590  C CB  . LEU A 1 75  ? 14.23984  7.70886   26.96024 1.000 33.44008 ? 102 LEU A CB  1 
ATOM   591  C CG  . LEU A 1 75  ? 14.15807  9.22127   27.11862 1.000 32.58883 ? 102 LEU A CG  1 
ATOM   592  C CD1 . LEU A 1 75  ? 15.37302  9.86272   26.44373 1.000 38.18421 ? 102 LEU A CD1 1 
ATOM   593  C CD2 . LEU A 1 75  ? 12.88386  9.76631   26.53577 1.000 31.53794 ? 102 LEU A CD2 1 
ATOM   594  N N   . VAL A 1 76  ? 12.34561  4.97292   26.59040 1.000 30.43390 ? 103 VAL A N   1 
ATOM   595  C CA  . VAL A 1 76  ? 12.42648  3.55244   26.26488 1.000 28.38869 ? 103 VAL A CA  1 
ATOM   596  C C   . VAL A 1 76  ? 12.80641  3.42049   24.79017 1.000 32.84099 ? 103 VAL A C   1 
ATOM   597  O O   . VAL A 1 76  ? 13.71845  4.10852   24.30964 1.000 34.13040 ? 103 VAL A O   1 
ATOM   598  C CB  . VAL A 1 76  ? 11.12794  2.80789   26.64564 1.000 30.65705 ? 103 VAL A CB  1 
ATOM   599  C CG1 . VAL A 1 76  ? 11.05724  2.66688   28.18165 1.000 31.87977 ? 103 VAL A CG1 1 
ATOM   600  C CG2 . VAL A 1 76  ? 9.86272   3.53242   26.14635 1.000 29.47317 ? 103 VAL A CG2 1 
ATOM   601  N N   . ASN A 1 77  ? 12.14609  2.52000   24.06488 1.000 28.96758 ? 104 ASN A N   1 
ATOM   602  C CA  . ASN A 1 77  ? 12.64023  2.14454   22.73656 1.000 35.09385 ? 104 ASN A CA  1 
ATOM   603  C C   . ASN A 1 77  ? 12.16998  3.06021   21.61217 1.000 37.20335 ? 104 ASN A C   1 
ATOM   604  O O   . ASN A 1 77  ? 12.80392  3.06846   20.55436 1.000 39.87471 ? 104 ASN A O   1 
ATOM   605  C CB  . ASN A 1 77  ? 12.22419  0.70653   22.38332 1.000 31.94883 ? 104 ASN A CB  1 
ATOM   606  C CG  . ASN A 1 77  ? 10.71821  0.52804   22.33586 1.000 29.94324 ? 104 ASN A CG  1 
ATOM   607  O OD1 . ASN A 1 77  ? 9.98377   1.18953   23.07152 1.000 29.70254 ? 104 ASN A OD1 1 
ATOM   608  N ND2 . ASN A 1 77  ? 10.24409  -0.36516  21.46227 1.000 32.86694 ? 104 ASN A ND2 1 
ATOM   609  N N   . TYR A 1 78  ? 11.05943  3.78685   21.78495 1.000 29.26811 ? 105 TYR A N   1 
ATOM   610  C CA  . TYR A 1 78  ? 10.49395  4.60487   20.70558 1.000 28.36157 ? 105 TYR A CA  1 
ATOM   611  C C   . TYR A 1 78  ? 9.84963   5.83710   21.34248 1.000 26.81861 ? 105 TYR A C   1 
ATOM   612  O O   . TYR A 1 78  ? 8.74471   5.74179   21.88810 1.000 29.26843 ? 105 TYR A O   1 
ATOM   613  C CB  . TYR A 1 78  ? 9.48171   3.82012   19.87376 1.000 26.53975 ? 105 TYR A CB  1 
ATOM   614  C CG  . TYR A 1 78  ? 9.01412   4.61834   18.67889 1.000 30.24134 ? 105 TYR A CG  1 
ATOM   615  C CD1 . TYR A 1 78  ? 9.92319   5.00333   17.70066 1.000 35.04419 ? 105 TYR A CD1 1 
ATOM   616  C CD2 . TYR A 1 78  ? 7.68640   5.02686   18.54925 1.000 28.19766 ? 105 TYR A CD2 1 
ATOM   617  C CE1 . TYR A 1 78  ? 9.52967   5.76322   16.61430 1.000 33.21382 ? 105 TYR A CE1 1 
ATOM   618  C CE2 . TYR A 1 78  ? 7.27852   5.77810   17.44281 1.000 35.63510 ? 105 TYR A CE2 1 
ATOM   619  C CZ  . TYR A 1 78  ? 8.20681   6.14402   16.48442 1.000 45.78782 ? 105 TYR A CZ  1 
ATOM   620  O OH  . TYR A 1 78  ? 7.82683   6.89883   15.38669 1.000 42.36362 ? 105 TYR A OH  1 
ATOM   621  N N   . ASN A 1 79  ? 10.53476  6.97796   21.27805 1.000 25.34337 ? 106 ASN A N   1 
ATOM   622  C CA  . ASN A 1 79  ? 10.11428  8.17609   22.01340 1.000 28.32632 ? 106 ASN A CA  1 
ATOM   623  C C   . ASN A 1 79  ? 10.27411  9.40789   21.14399 1.000 23.89100 ? 106 ASN A C   1 
ATOM   624  O O   . ASN A 1 79  ? 11.03162  10.31526  21.47615 1.000 29.27303 ? 106 ASN A O   1 
ATOM   625  C CB  . ASN A 1 79  ? 10.93348  8.35461   23.28708 1.000 33.22598 ? 106 ASN A CB  1 
ATOM   626  C CG  . ASN A 1 79  ? 11.60278  7.10570   23.71268 1.000 30.76948 ? 106 ASN A CG  1 
ATOM   627  O OD1 . ASN A 1 79  ? 10.96594  6.20522   24.23382 1.000 32.41562 ? 106 ASN A OD1 1 
ATOM   628  N ND2 . ASN A 1 79  ? 12.90499  7.03091   23.48798 1.000 35.40103 ? 106 ASN A ND2 1 
ATOM   629  N N   . PRO A 1 80  ? 9.54141   9.48295   20.03169 1.000 23.07936 ? 107 PRO A N   1 
ATOM   630  C CA  . PRO A 1 80  ? 9.81312   10.55056  19.06529 1.000 24.60721 ? 107 PRO A CA  1 
ATOM   631  C C   . PRO A 1 80  ? 9.50859   11.93389  19.58139 1.000 29.87067 ? 107 PRO A C   1 
ATOM   632  O O   . PRO A 1 80  ? 10.18061  12.89550  19.17204 1.000 32.42356 ? 107 PRO A O   1 
ATOM   633  C CB  . PRO A 1 80  ? 8.91942   10.16476  17.87172 1.000 27.67390 ? 107 PRO A CB  1 
ATOM   634  C CG  . PRO A 1 80  ? 7.83203   9.34910   18.45347 1.000 31.85639 ? 107 PRO A CG  1 
ATOM   635  C CD  . PRO A 1 80  ? 8.46583   8.57808   19.58440 1.000 24.58160 ? 107 PRO A CD  1 
ATOM   636  N N   . ILE A 1 81  ? 8.54460   12.07869  20.48433 1.000 25.03354 ? 108 ILE A N   1 
ATOM   637  C CA  . ILE A 1 81  ? 8.23117   13.38020  21.05479 1.000 25.77224 ? 108 ILE A CA  1 
ATOM   638  C C   . ILE A 1 81  ? 8.93560   13.58957  22.39158 1.000 25.02785 ? 108 ILE A C   1 
ATOM   639  O O   . ILE A 1 81  ? 9.49349   14.66344  22.63421 1.000 25.89269 ? 108 ILE A O   1 
ATOM   640  C CB  . ILE A 1 81  ? 6.70576   13.57640  21.20507 1.000 24.26464 ? 108 ILE A CB  1 
ATOM   641  C CG1 . ILE A 1 81  ? 5.99431   13.32642  19.86112 1.000 27.24519 ? 108 ILE A CG1 1 
ATOM   642  C CG2 . ILE A 1 81  ? 6.43503   14.98492  21.74212 1.000 28.92407 ? 108 ILE A CG2 1 
ATOM   643  C CD1 . ILE A 1 81  ? 6.46913   14.20996  18.70611 1.000 28.36632 ? 108 ILE A CD1 1 
ATOM   644  N N   . ALA A 1 82  ? 8.92282   12.57431  23.26030 1.000 23.08211 ? 109 ALA A N   1 
ATOM   645  C CA  . ALA A 1 82  ? 9.55161   12.71009  24.57409 1.000 25.27539 ? 109 ALA A CA  1 
ATOM   646  C C   . ALA A 1 82  ? 11.02819  13.06824  24.45528 1.000 26.88347 ? 109 ALA A C   1 
ATOM   647  O O   . ALA A 1 82  ? 11.54815  13.85930  25.25854 1.000 27.80442 ? 109 ALA A O   1 
ATOM   648  C CB  . ALA A 1 82  ? 9.36884   11.41724  25.37316 1.000 23.30876 ? 109 ALA A CB  1 
ATOM   649  N N   A GLU A 1 83  ? 11.70850  12.50645  23.44628 0.554 29.88091 ? 110 GLU A N   1 
ATOM   650  N N   B GLU A 1 83  ? 11.71902  12.52618  23.45074 0.446 29.88591 ? 110 GLU A N   1 
ATOM   651  C CA  A GLU A 1 83  ? 13.12097  12.78314  23.20392 0.554 29.93433 ? 110 GLU A CA  1 
ATOM   652  C CA  B GLU A 1 83  ? 13.14129  12.81262  23.31168 0.446 29.98555 ? 110 GLU A CA  1 
ATOM   653  C C   A GLU A 1 83  ? 13.38174  14.27591  23.07860 0.554 31.52056 ? 110 GLU A C   1 
ATOM   654  C C   B GLU A 1 83  ? 13.40630  14.28792  23.05326 0.446 31.56095 ? 110 GLU A C   1 
ATOM   655  O O   A GLU A 1 83  ? 14.44141  14.76457  23.49185 0.554 35.92475 ? 110 GLU A O   1 
ATOM   656  O O   B GLU A 1 83  ? 14.50690  14.77059  23.34688 0.446 35.73718 ? 110 GLU A O   1 
ATOM   657  C CB  A GLU A 1 83  ? 13.56807  12.05078  21.92847 0.554 33.43653 ? 110 GLU A CB  1 
ATOM   658  C CB  B GLU A 1 83  ? 13.74039  11.96040  22.19456 0.446 33.95323 ? 110 GLU A CB  1 
ATOM   659  C CG  A GLU A 1 83  ? 14.86343  12.53681  21.29709 0.554 40.00538 ? 110 GLU A CG  1 
ATOM   660  C CG  B GLU A 1 83  ? 14.42481  10.70744  22.70665 0.446 42.03766 ? 110 GLU A CG  1 
ATOM   661  C CD  A GLU A 1 83  ? 16.10108  11.90628  21.90694 0.554 49.37484 ? 110 GLU A CD  1 
ATOM   662  C CD  B GLU A 1 83  ? 14.52252  9.62367   21.65642 0.446 42.70345 ? 110 GLU A CD  1 
ATOM   663  O OE1 A GLU A 1 83  ? 15.98999  10.80272  22.48072 0.554 41.58252 ? 110 GLU A OE1 1 
ATOM   664  O OE1 B GLU A 1 83  ? 14.55408  9.96118   20.45014 0.446 41.97716 ? 110 GLU A OE1 1 
ATOM   665  O OE2 A GLU A 1 83  ? 17.18808  12.52062  21.80375 0.554 47.66181 ? 110 GLU A OE2 1 
ATOM   666  O OE2 B GLU A 1 83  ? 14.55997  8.43591   22.04690 0.446 42.71459 ? 110 GLU A OE2 1 
ATOM   667  N N   . LYS A 1 84  ? 12.42372  15.01837  22.52415 1.000 29.56956 ? 111 LYS A N   1 
ATOM   668  C CA  . LYS A 1 84  ? 12.58652  16.44818  22.29019 1.000 31.67686 ? 111 LYS A CA  1 
ATOM   669  C C   . LYS A 1 84  ? 12.45157  17.25944  23.56572 1.000 31.19166 ? 111 LYS A C   1 
ATOM   670  O O   . LYS A 1 84  ? 12.66103  18.48243  23.53624 1.000 32.94697 ? 111 LYS A O   1 
ATOM   671  C CB  . LYS A 1 84  ? 11.54325  16.93953  21.28275 1.000 30.72256 ? 111 LYS A CB  1 
ATOM   672  C CG  . LYS A 1 84  ? 11.42276  16.10362  20.02392 1.000 34.25475 ? 111 LYS A CG  1 
ATOM   673  C CD  . LYS A 1 84  ? 10.57818  16.83789  18.98672 1.000 34.96712 ? 111 LYS A CD  1 
ATOM   674  C CE  . LYS A 1 84  ? 10.27787  15.95897  17.79405 1.000 40.92518 ? 111 LYS A CE  1 
ATOM   675  N NZ  . LYS A 1 84  ? 11.44926  15.89105  16.88748 1.000 48.57363 ? 111 LYS A NZ  1 
ATOM   676  N N   . HIS A 1 85  ? 12.09961  16.61162  24.68680 1.000 29.74612 ? 112 HIS A N   1 
ATOM   677  C CA  . HIS A 1 85  ? 11.82959  17.33572  25.92051 1.000 32.89759 ? 112 HIS A CA  1 
ATOM   678  C C   . HIS A 1 85  ? 12.54371  16.71530  27.10601 1.000 32.47088 ? 112 HIS A C   1 
ATOM   679  O O   . HIS A 1 85  ? 12.16921  16.98521  28.25166 1.000 34.75457 ? 112 HIS A O   1 
ATOM   680  C CB  . HIS A 1 85  ? 10.32518  17.41918  26.16924 1.000 30.23134 ? 112 HIS A CB  1 
ATOM   681  C CG  . HIS A 1 85  ? 9.60165   18.10620  25.05650 1.000 36.61110 ? 112 HIS A CG  1 
ATOM   682  N ND1 . HIS A 1 85  ? 9.50176   19.47774  24.97465 1.000 36.59466 ? 112 HIS A ND1 1 
ATOM   683  C CD2 . HIS A 1 85  ? 9.00969   17.61766  23.93921 1.000 35.76756 ? 112 HIS A CD2 1 
ATOM   684  C CE1 . HIS A 1 85  ? 8.87288   19.80709  23.85729 1.000 42.00282 ? 112 HIS A CE1 1 
ATOM   685  N NE2 . HIS A 1 85  ? 8.56682   18.69957  23.20914 1.000 39.92325 ? 112 HIS A NE2 1 
ATOM   686  N N   A VAL A 1 86  ? 13.56518  15.89708  26.86272 0.458 34.40197 ? 113 VAL A N   1 
ATOM   687  N N   B VAL A 1 86  ? 13.58094  15.91371  26.84529 0.542 34.38340 ? 113 VAL A N   1 
ATOM   688  C CA  A VAL A 1 86  ? 14.29919  15.31435  27.97374 0.458 36.83542 ? 113 VAL A CA  1 
ATOM   689  C CA  B VAL A 1 86  ? 14.41028  15.36058  27.90998 0.542 36.96556 ? 113 VAL A CA  1 
ATOM   690  C C   A VAL A 1 86  ? 14.96073  16.42982  28.77480 0.458 37.43561 ? 113 VAL A C   1 
ATOM   691  C C   B VAL A 1 86  ? 14.95574  16.48630  28.77702 0.542 37.47125 ? 113 VAL A C   1 
ATOM   692  O O   A VAL A 1 86  ? 15.41392  17.44641  28.22633 0.458 39.37880 ? 113 VAL A O   1 
ATOM   693  O O   B VAL A 1 86  ? 15.35244  17.55169  28.27702 0.542 39.22982 ? 113 VAL A O   1 
ATOM   694  C CB  A VAL A 1 86  ? 15.31980  14.28144  27.46996 0.458 38.74761 ? 113 VAL A CB  1 
ATOM   695  C CB  B VAL A 1 86  ? 15.56090  14.52913  27.31670 0.542 39.15418 ? 113 VAL A CB  1 
ATOM   696  C CG1 A VAL A 1 86  ? 16.44991  14.96849  26.72123 0.458 38.30463 ? 113 VAL A CG1 1 
ATOM   697  C CG1 B VAL A 1 86  ? 16.42353  13.93358  28.42948 0.542 40.60603 ? 113 VAL A CG1 1 
ATOM   698  C CG2 A VAL A 1 86  ? 15.84427  13.44595  28.63280 0.458 36.34504 ? 113 VAL A CG2 1 
ATOM   699  C CG2 B VAL A 1 86  ? 15.02763  13.44584  26.39034 0.542 38.03733 ? 113 VAL A CG2 1 
ATOM   700  N N   . ASN A 1 87  ? 14.96360  16.26084  30.09523 1.000 35.08967 ? 114 ASN A N   1 
ATOM   701  C CA  . ASN A 1 87  ? 15.41906  17.25907  31.06549 1.000 35.01184 ? 114 ASN A CA  1 
ATOM   702  C C   . ASN A 1 87  ? 14.58720  18.52946  31.01521 1.000 40.23404 ? 114 ASN A C   1 
ATOM   703  O O   . ASN A 1 87  ? 15.04730  19.59111  31.43003 1.000 42.66753 ? 114 ASN A O   1 
ATOM   704  C CB  . ASN A 1 87  ? 16.90352  17.59231  30.89650 1.000 43.22948 ? 114 ASN A CB  1 
ATOM   705  C CG  . ASN A 1 87  ? 17.78759  16.45547  31.31295 1.000 47.79555 ? 114 ASN A CG  1 
ATOM   706  O OD1 . ASN A 1 87  ? 18.64759  16.01494  30.55537 1.000 60.60190 ? 114 ASN A OD1 1 
ATOM   707  N ND2 . ASN A 1 87  ? 17.56760  15.95057  32.52113 1.000 50.25845 ? 114 ASN A ND2 1 
ATOM   708  N N   . GLY A 1 88  ? 13.36793  18.43378  30.50147 1.000 33.09342 ? 115 GLY A N   1 
ATOM   709  C CA  . GLY A 1 88  ? 12.37370  19.47618  30.62069 1.000 39.38310 ? 115 GLY A CA  1 
ATOM   710  C C   . GLY A 1 88  ? 11.06340  18.84453  31.02320 1.000 33.19832 ? 115 GLY A C   1 
ATOM   711  O O   . GLY A 1 88  ? 11.04269  17.70987  31.52381 1.000 32.99521 ? 115 GLY A O   1 
ATOM   712  N N   . THR A 1 89  ? 9.94858   19.51236  30.75412 1.000 34.65225 ? 116 THR A N   1 
ATOM   713  C CA  . THR A 1 89  ? 8.66137   18.94233  31.11891 1.000 31.43047 ? 116 THR A CA  1 
ATOM   714  C C   . THR A 1 89  ? 7.73148   18.90168  29.91359 1.000 30.98032 ? 116 THR A C   1 
ATOM   715  O O   . THR A 1 89  ? 7.92303   19.60414  28.91406 1.000 34.40453 ? 116 THR A O   1 
ATOM   716  C CB  . THR A 1 89  ? 7.97734   19.72737  32.23729 1.000 38.85280 ? 116 THR A CB  1 
ATOM   717  O OG1 . THR A 1 89  ? 7.71013   21.05153  31.76911 1.000 37.85222 ? 116 THR A OG1 1 
ATOM   718  C CG2 . THR A 1 89  ? 8.86139   19.79103  33.47902 1.000 34.36071 ? 116 THR A CG2 1 
ATOM   719  N N   . MET A 1 90  ? 6.71114   18.06578  30.04229 1.000 28.53420 ? 117 MET A N   1 
ATOM   720  C CA  . MET A 1 90  ? 5.58178   18.04130  29.12275 1.000 27.59975 ? 117 MET A CA  1 
ATOM   721  C C   . MET A 1 90  ? 4.32758   17.97628  29.98265 1.000 28.23823 ? 117 MET A C   1 
ATOM   722  O O   . MET A 1 90  ? 4.34097   17.33553  31.03652 1.000 29.31763 ? 117 MET A O   1 
ATOM   723  C CB  . MET A 1 90  ? 5.64656   16.82338  28.19489 1.000 26.75096 ? 117 MET A CB  1 
ATOM   724  C CG  . MET A 1 90  ? 6.85915   16.83160  27.25307 1.000 30.37553 ? 117 MET A CG  1 
ATOM   725  S SD  . MET A 1 90  ? 6.90882   15.27821  26.30810 1.000 31.55403 ? 117 MET A SD  1 
ATOM   726  C CE  . MET A 1 90  ? 5.35233   15.42077  25.40469 1.000 30.66498 ? 117 MET A CE  1 
ATOM   727  N N   . THR A 1 91  ? 3.24875   18.63788  29.54838 1.000 26.57623 ? 118 THR A N   1 
ATOM   728  C CA  . THR A 1 91  ? 2.00902   18.52498  30.30238 1.000 28.08074 ? 118 THR A CA  1 
ATOM   729  C C   . THR A 1 91  ? 1.35669   17.17739  30.01161 1.000 28.32775 ? 118 THR A C   1 
ATOM   730  O O   . THR A 1 91  ? 1.71672   16.47689  29.05209 1.000 26.11678 ? 118 THR A O   1 
ATOM   731  C CB  . THR A 1 91  ? 1.04530   19.64932  29.95484 1.000 29.42508 ? 118 THR A CB  1 
ATOM   732  O OG1 . THR A 1 91  ? 0.58384   19.45809  28.61111 1.000 28.06744 ? 118 THR A OG1 1 
ATOM   733  C CG2 . THR A 1 91  ? 1.75029   21.04498  30.05858 1.000 32.25702 ? 118 THR A CG2 1 
ATOM   734  N N   . LEU A 1 92  ? 0.37813   16.80515  30.84527 1.000 24.80569 ? 119 LEU A N   1 
ATOM   735  C CA  . LEU A 1 92  ? -0.34608  15.56253  30.57168 1.000 25.31680 ? 119 LEU A CA  1 
ATOM   736  C C   . LEU A 1 92  ? -1.11698  15.64436  29.25666 1.000 25.43781 ? 119 LEU A C   1 
ATOM   737  O O   . LEU A 1 92  ? -1.28162  14.63119  28.57379 1.000 24.75748 ? 119 LEU A O   1 
ATOM   738  C CB  . LEU A 1 92  ? -1.29033  15.21259  31.72518 1.000 26.36749 ? 119 LEU A CB  1 
ATOM   739  C CG  . LEU A 1 92  ? -0.61762  14.55259  32.91991 1.000 27.18920 ? 119 LEU A CG  1 
ATOM   740  C CD1 . LEU A 1 92  ? -1.56113  14.52515  34.10523 1.000 25.39975 ? 119 LEU A CD1 1 
ATOM   741  C CD2 . LEU A 1 92  ? -0.15173  13.15706  32.61471 1.000 25.38868 ? 119 LEU A CD2 1 
ATOM   742  N N   . ALA A 1 93  ? -1.60227  16.82552  28.88171 1.000 25.11138 ? 120 ALA A N   1 
ATOM   743  C CA  . ALA A 1 93  ? -2.20280  16.94759  27.55331 1.000 23.85578 ? 120 ALA A CA  1 
ATOM   744  C C   . ALA A 1 93  ? -1.17879  16.68291  26.45960 1.000 26.77772 ? 120 ALA A C   1 
ATOM   745  O O   . ALA A 1 93  ? -1.47727  15.96571  25.49656 1.000 27.12180 ? 120 ALA A O   1 
ATOM   746  C CB  . ALA A 1 93  ? -2.84928  18.32120  27.36208 1.000 29.99688 ? 120 ALA A CB  1 
ATOM   747  N N   . GLU A 1 94  ? 0.03528   17.24593  26.58619 1.000 26.19898 ? 121 GLU A N   1 
ATOM   748  C CA  . GLU A 1 94  ? 1.05696   17.01009  25.56436 1.000 25.94135 ? 121 GLU A CA  1 
ATOM   749  C C   . GLU A 1 94  ? 1.46288   15.53726  25.51477 1.000 22.92820 ? 121 GLU A C   1 
ATOM   750  O O   . GLU A 1 94  ? 1.71356   15.00022  24.42512 1.000 24.26225 ? 121 GLU A O   1 
ATOM   751  C CB  . GLU A 1 94  ? 2.27942   17.89891  25.80610 1.000 27.74875 ? 121 GLU A CB  1 
ATOM   752  C CG  . GLU A 1 94  ? 1.98040   19.41904  25.52703 1.000 27.38745 ? 121 GLU A CG  1 
ATOM   753  C CD  . GLU A 1 94  ? 2.98910   20.35485  26.13591 1.000 39.41128 ? 121 GLU A CD  1 
ATOM   754  O OE1 . GLU A 1 94  ? 3.79957   19.93772  26.98696 1.000 32.47219 ? 121 GLU A OE1 1 
ATOM   755  O OE2 . GLU A 1 94  ? 2.95758   21.54637  25.76735 1.000 45.95907 ? 121 GLU A OE2 1 
ATOM   756  N N   . LEU A 1 95  ? 1.52498   14.87297  26.68356 1.000 23.37110 ? 122 LEU A N   1 
ATOM   757  C CA  . LEU A 1 95  ? 1.85626   13.44993  26.72460 1.000 20.07670 ? 122 LEU A CA  1 
ATOM   758  C C   . LEU A 1 95  ? 0.75125   12.61390  26.10948 1.000 19.14423 ? 122 LEU A C   1 
ATOM   759  O O   . LEU A 1 95  ? 1.02838   11.59802  25.45069 1.000 22.03705 ? 122 LEU A O   1 
ATOM   760  C CB  . LEU A 1 95  ? 2.10110   13.02921  28.18619 1.000 20.35699 ? 122 LEU A CB  1 
ATOM   761  C CG  . LEU A 1 95  ? 3.43100   13.58163  28.72814 1.000 27.47563 ? 122 LEU A CG  1 
ATOM   762  C CD1 . LEU A 1 95  ? 3.44693   13.54818  30.24421 1.000 27.24527 ? 122 LEU A CD1 1 
ATOM   763  C CD2 . LEU A 1 95  ? 4.61926   12.77684  28.14834 1.000 28.78693 ? 122 LEU A CD2 1 
ATOM   764  N N   . SER A 1 96  ? -0.51234  12.98112  26.35870 1.000 22.98286 ? 123 SER A N   1 
ATOM   765  C CA  . SER A 1 96  ? -1.62048  12.22794  25.76259 1.000 20.57575 ? 123 SER A CA  1 
ATOM   766  C C   . SER A 1 96  ? -1.59171  12.35862  24.24371 1.000 23.31694 ? 123 SER A C   1 
ATOM   767  O O   . SER A 1 96  ? -1.78168  11.36596  23.51969 1.000 21.45157 ? 123 SER A O   1 
ATOM   768  C CB  . SER A 1 96  ? -2.96500  12.70760  26.30208 1.000 24.04872 ? 123 SER A CB  1 
ATOM   769  O OG  . SER A 1 96  ? -2.97324  12.54525  27.70988 1.000 25.25245 ? 123 SER A OG  1 
ATOM   770  N N   . ALA A 1 97  ? -1.40912  13.58644  23.75399 1.000 23.96712 ? 124 ALA A N   1 
ATOM   771  C CA  . ALA A 1 97  ? -1.26643  13.81485  22.32552 1.000 23.55757 ? 124 ALA A CA  1 
ATOM   772  C C   . ALA A 1 97  ? -0.10687  13.00963  21.73955 1.000 20.85878 ? 124 ALA A C   1 
ATOM   773  O O   . ALA A 1 97  ? -0.22766  12.45837  20.64478 1.000 23.74794 ? 124 ALA A O   1 
ATOM   774  C CB  . ALA A 1 97  ? -1.08388  15.31848  22.06132 1.000 25.96608 ? 124 ALA A CB  1 
ATOM   775  N N   . ALA A 1 98  ? 1.04312   12.98774  22.41570 1.000 22.01344 ? 125 ALA A N   1 
ATOM   776  C CA  . ALA A 1 98  ? 2.19100   12.28599  21.86459 1.000 22.69391 ? 125 ALA A CA  1 
ATOM   777  C C   . ALA A 1 98  ? 1.91200   10.79545  21.80743 1.000 23.38701 ? 125 ALA A C   1 
ATOM   778  O O   . ALA A 1 98  ? 2.23265   10.12013  20.81873 1.000 19.97009 ? 125 ALA A O   1 
ATOM   779  C CB  . ALA A 1 98  ? 3.43676   12.52912  22.70586 1.000 22.16019 ? 125 ALA A CB  1 
ATOM   780  N N   . ALA A 1 99  ? 1.35489   10.26830  22.88541 1.000 18.46933 ? 126 ALA A N   1 
ATOM   781  C CA  . ALA A 1 99  ? 1.00194   8.85251   22.92754 1.000 16.30002 ? 126 ALA A CA  1 
ATOM   782  C C   . ALA A 1 99  ? 0.06362   8.49779   21.78973 1.000 20.15091 ? 126 ALA A C   1 
ATOM   783  O O   . ALA A 1 99  ? 0.27092   7.49879   21.08986 1.000 20.12645 ? 126 ALA A O   1 
ATOM   784  C CB  . ALA A 1 99  ? 0.34942   8.51677   24.25889 1.000 16.00908 ? 126 ALA A CB  1 
ATOM   785  N N   . LEU A 1 100 ? -0.96800  9.31527   21.57107 1.000 19.05751 ? 127 LEU A N   1 
ATOM   786  C CA  . LEU A 1 100 ? -1.96503  8.94632   20.55778 1.000 18.56400 ? 127 LEU A CA  1 
ATOM   787  C C   . LEU A 1 100 ? -1.48436  9.22987   19.14775 1.000 18.11688 ? 127 LEU A C   1 
ATOM   788  O O   . LEU A 1 100 ? -1.71731  8.42173   18.23701 1.000 22.46685 ? 127 LEU A O   1 
ATOM   789  C CB  . LEU A 1 100 ? -3.27821  9.68898   20.80151 1.000 18.01544 ? 127 LEU A CB  1 
ATOM   790  C CG  . LEU A 1 100 ? -4.02101  9.23257   22.06492 1.000 18.15125 ? 127 LEU A CG  1 
ATOM   791  C CD1 . LEU A 1 100 ? -5.18437  10.18961  22.36387 1.000 26.24771 ? 127 LEU A CD1 1 
ATOM   792  C CD2 . LEU A 1 100 ? -4.48745  7.79518   22.00254 1.000 25.55881 ? 127 LEU A CD2 1 
ATOM   793  N N   . GLN A 1 101 ? -0.89615  10.41096  18.90498 1.000 20.47364 ? 128 GLN A N   1 
ATOM   794  C CA  . GLN A 1 101 ? -0.68366  10.80623  17.51308 1.000 23.14803 ? 128 GLN A CA  1 
ATOM   795  C C   . GLN A 1 101 ? 0.65730   10.38436  16.96730 1.000 23.82586 ? 128 GLN A C   1 
ATOM   796  O O   . GLN A 1 101 ? 0.81443   10.33282  15.73958 1.000 23.54622 ? 128 GLN A O   1 
ATOM   797  C CB  . GLN A 1 101 ? -0.81433  12.32313  17.33357 1.000 23.63024 ? 128 GLN A CB  1 
ATOM   798  C CG  . GLN A 1 101 ? -2.17881  12.81174  17.77901 1.000 24.81728 ? 128 GLN A CG  1 
ATOM   799  C CD  . GLN A 1 101 ? -2.33177  14.32698  17.65702 1.000 31.67522 ? 128 GLN A CD  1 
ATOM   800  O OE1 . GLN A 1 101 ? -1.36950  15.08418  17.85318 1.000 35.38790 ? 128 GLN A OE1 1 
ATOM   801  N NE2 . GLN A 1 101 ? -3.54741  14.76979  17.35174 1.000 31.06286 ? 128 GLN A NE2 1 
ATOM   802  N N   . TYR A 1 102 ? 1.63287   10.12766  17.82812 1.000 22.13454 ? 129 TYR A N   1 
ATOM   803  C CA  . TYR A 1 102 ? 2.93927   9.64410   17.39691 1.000 23.73686 ? 129 TYR A CA  1 
ATOM   804  C C   . TYR A 1 102 ? 3.28737   8.27886   17.96992 1.000 19.93776 ? 129 TYR A C   1 
ATOM   805  O O   . TYR A 1 102 ? 4.35893   7.73865   17.66398 1.000 23.36752 ? 129 TYR A O   1 
ATOM   806  C CB  . TYR A 1 102 ? 4.02419   10.66270  17.77543 1.000 23.25255 ? 129 TYR A CB  1 
ATOM   807  C CG  . TYR A 1 102 ? 3.85167   11.93063  17.02399 1.000 28.99458 ? 129 TYR A CG  1 
ATOM   808  C CD1 . TYR A 1 102 ? 4.45349   12.09370  15.78771 1.000 29.00841 ? 129 TYR A CD1 1 
ATOM   809  C CD2 . TYR A 1 102 ? 3.03927   12.95506  17.51814 1.000 27.55174 ? 129 TYR A CD2 1 
ATOM   810  C CE1 . TYR A 1 102 ? 4.29033   13.25030  15.06052 1.000 29.76465 ? 129 TYR A CE1 1 
ATOM   811  C CE2 . TYR A 1 102 ? 2.86533   14.15663  16.76766 1.000 31.11300 ? 129 TYR A CE2 1 
ATOM   812  C CZ  . TYR A 1 102 ? 3.49300   14.27018  15.54667 1.000 30.15463 ? 129 TYR A CZ  1 
ATOM   813  O OH  . TYR A 1 102 ? 3.37772   15.42071  14.75238 1.000 40.55610 ? 129 TYR A OH  1 
ATOM   814  N N   . SER A 1 103 ? 2.40270   7.68187   18.75716 1.000 20.28960 ? 130 SER A N   1 
ATOM   815  C CA  . SER A 1 103 ? 2.64360   6.36151   19.35192 1.000 18.71385 ? 130 SER A CA  1 
ATOM   816  C C   . SER A 1 103 ? 3.88589   6.36706   20.24416 1.000 19.51665 ? 130 SER A C   1 
ATOM   817  O O   . SER A 1 103 ? 4.60304   5.37412   20.34256 1.000 21.83114 ? 130 SER A O   1 
ATOM   818  C CB  . SER A 1 103 ? 2.72135   5.26049   18.29007 1.000 20.63096 ? 130 SER A CB  1 
ATOM   819  O OG  . SER A 1 103 ? 2.03400   4.10037   18.81456 1.000 22.36688 ? 130 SER A OG  1 
ATOM   820  N N   . ASP A 1 104 ? 4.08989   7.47050   20.97079 1.000 19.85339 ? 131 ASP A N   1 
ATOM   821  C CA  . ASP A 1 104 ? 5.27151   7.64299   21.80631 1.000 19.02923 ? 131 ASP A CA  1 
ATOM   822  C C   . ASP A 1 104 ? 5.16666   6.74729   23.03156 1.000 20.78401 ? 131 ASP A C   1 
ATOM   823  O O   . ASP A 1 104 ? 4.16137   6.79705   23.76384 1.000 18.72028 ? 131 ASP A O   1 
ATOM   824  C CB  . ASP A 1 104 ? 5.40516   9.12116   22.20085 1.000 19.96641 ? 131 ASP A CB  1 
ATOM   825  C CG  . ASP A 1 104 ? 6.69543   9.42669   22.93588 1.000 25.41178 ? 131 ASP A CG  1 
ATOM   826  O OD1 . ASP A 1 104 ? 6.91496   8.88296   24.02213 1.000 21.82954 ? 131 ASP A OD1 1 
ATOM   827  O OD2 . ASP A 1 104 ? 7.48942   10.27358  22.46298 1.000 24.19893 ? 131 ASP A OD2 1 
ATOM   828  N N   . ASN A 1 105 ? 6.17639   5.88844   23.22272 1.000 18.22981 ? 132 ASN A N   1 
ATOM   829  C CA  . ASN A 1 105 ? 6.09624   4.89493   24.28752 1.000 17.74554 ? 132 ASN A CA  1 
ATOM   830  C C   . ASN A 1 105 ? 6.42861   5.46923   25.66563 1.000 20.75274 ? 132 ASN A C   1 
ATOM   831  O O   . ASN A 1 105 ? 5.93744   4.95009   26.68986 1.000 18.23059 ? 132 ASN A O   1 
ATOM   832  C CB  . ASN A 1 105 ? 7.03742   3.71565   23.99423 1.000 20.97238 ? 132 ASN A CB  1 
ATOM   833  C CG  . ASN A 1 105 ? 6.45716   2.74730   22.98872 1.000 24.78601 ? 132 ASN A CG  1 
ATOM   834  O OD1 . ASN A 1 105 ? 5.24941   2.79123   22.69724 1.000 20.88559 ? 132 ASN A OD1 1 
ATOM   835  N ND2 . ASN A 1 105 ? 7.29303   1.82535   22.47976 1.000 21.79477 ? 132 ASN A ND2 1 
ATOM   836  N N   . THR A 1 106 ? 7.33676   6.44695   25.73531 1.000 18.19119 ? 133 THR A N   1 
ATOM   837  C CA  . THR A 1 106 ? 7.58794   7.12822   27.00940 1.000 19.02280 ? 133 THR A CA  1 
ATOM   838  C C   . THR A 1 106 ? 6.32585   7.83206   27.46889 1.000 20.59428 ? 133 THR A C   1 
ATOM   839  O O   . THR A 1 106 ? 5.96452   7.77014   28.64749 1.000 17.92772 ? 133 THR A O   1 
ATOM   840  C CB  . THR A 1 106 ? 8.75613   8.11014   26.88010 1.000 21.26795 ? 133 THR A CB  1 
ATOM   841  O OG1 . THR A 1 106 ? 9.94135   7.36321   26.61536 1.000 24.65369 ? 133 THR A OG1 1 
ATOM   842  C CG2 . THR A 1 106 ? 8.96235   8.95478   28.17223 1.000 24.13518 ? 133 THR A CG2 1 
ATOM   843  N N   . ALA A 1 107 ? 5.61510   8.47180   26.53489 1.000 18.55828 ? 134 ALA A N   1 
ATOM   844  C CA  . ALA A 1 107 ? 4.37101   9.13786   26.89474 1.000 19.90532 ? 134 ALA A CA  1 
ATOM   845  C C   . ALA A 1 107 ? 3.37510   8.14932   27.48823 1.000 20.52099 ? 134 ALA A C   1 
ATOM   846  O O   . ALA A 1 107 ? 2.73295   8.44651   28.51168 1.000 16.87249 ? 134 ALA A O   1 
ATOM   847  C CB  . ALA A 1 107 ? 3.77644   9.85462   25.67167 1.000 20.21714 ? 134 ALA A CB  1 
ATOM   848  N N   . MET A 1 108 ? 3.24623   6.97608   26.87717 1.000 16.30489 ? 135 MET A N   1 
ATOM   849  C CA  . MET A 1 108 ? 2.35094   5.96072   27.42107 1.000 13.76033 ? 135 MET A CA  1 
ATOM   850  C C   . MET A 1 108 ? 2.75958   5.57244   28.83606 1.000 15.35045 ? 135 MET A C   1 
ATOM   851  O O   . MET A 1 108 ? 1.89737   5.47506   29.73013 1.000 15.97342 ? 135 MET A O   1 
ATOM   852  C CB  . MET A 1 108 ? 2.33627   4.74281   26.48871 1.000 14.50360 ? 135 MET A CB  1 
ATOM   853  C CG  . MET A 1 108 ? 1.64223   3.50922   27.09996 1.000 17.01967 ? 135 MET A CG  1 
ATOM   854  S SD  . MET A 1 108 ? -0.11642  3.88069   27.41898 1.000 16.16223 ? 135 MET A SD  1 
ATOM   855  C CE  . MET A 1 108 ? -0.81342  2.21960   27.29478 1.000 17.38489 ? 135 MET A CE  1 
ATOM   856  N N   . ASN A 1 109 ? 4.05889   5.35936   29.07125 1.000 16.96468 ? 136 ASN A N   1 
ATOM   857  C CA  . ASN A 1 109 ? 4.46865   4.98041   30.42497 1.000 15.88015 ? 136 ASN A CA  1 
ATOM   858  C C   . ASN A 1 109 ? 4.17634   6.07592   31.44799 1.000 16.88824 ? 136 ASN A C   1 
ATOM   859  O O   . ASN A 1 109 ? 3.87393   5.75633   32.62369 1.000 17.76127 ? 136 ASN A O   1 
ATOM   860  C CB  . ASN A 1 109 ? 5.94519   4.59737   30.47060 1.000 16.56056 ? 136 ASN A CB  1 
ATOM   861  C CG  . ASN A 1 109 ? 6.17328   3.20142   29.94282 1.000 19.67833 ? 136 ASN A CG  1 
ATOM   862  O OD1 . ASN A 1 109 ? 5.20516   2.46648   29.70124 1.000 17.27095 ? 136 ASN A OD1 1 
ATOM   863  N ND2 . ASN A 1 109 ? 7.44786   2.82099   29.76702 1.000 19.95143 ? 136 ASN A ND2 1 
ATOM   864  N N   . LYS A 1 110 ? 4.27026   7.36156   31.05995 1.000 16.42750 ? 137 LYS A N   1 
ATOM   865  C CA  . LYS A 1 110 ? 3.87941   8.40263   32.00608 1.000 16.31304 ? 137 LYS A CA  1 
ATOM   866  C C   . LYS A 1 110 ? 2.37479   8.38458   32.28002 1.000 17.18702 ? 137 LYS A C   1 
ATOM   867  O O   . LYS A 1 110 ? 1.94751   8.68726   33.40258 1.000 19.21139 ? 137 LYS A O   1 
ATOM   868  C CB  . LYS A 1 110 ? 4.28739   9.80299   31.48887 1.000 17.02139 ? 137 LYS A CB  1 
ATOM   869  C CG  . LYS A 1 110 ? 5.78384   9.98644   31.35992 1.000 21.59897 ? 137 LYS A CG  1 
ATOM   870  C CD  . LYS A 1 110 ? 6.39116   9.99654   32.74326 1.000 26.11024 ? 137 LYS A CD  1 
ATOM   871  C CE  . LYS A 1 110 ? 7.85341   10.41364  32.67650 1.000 31.90584 ? 137 LYS A CE  1 
ATOM   872  N NZ  . LYS A 1 110 ? 8.44558   10.49301  34.04476 1.000 38.64594 ? 137 LYS A NZ  1 
ATOM   873  N N   . LEU A 1 111 ? 1.55458   8.14152   31.25705 1.000 16.70573 ? 138 LEU A N   1 
ATOM   874  C CA  . LEU A 1 111 ? 0.11395   8.02111   31.48387 1.000 16.85427 ? 138 LEU A CA  1 
ATOM   875  C C   . LEU A 1 111 ? -0.19281  6.85168   32.42373 1.000 16.80643 ? 138 LEU A C   1 
ATOM   876  O O   . LEU A 1 111 ? -1.01068  6.98322   33.33883 1.000 17.85317 ? 138 LEU A O   1 
ATOM   877  C CB  . LEU A 1 111 ? -0.61120  7.83640   30.15920 1.000 16.27668 ? 138 LEU A CB  1 
ATOM   878  C CG  . LEU A 1 111 ? -0.42722  8.98169   29.18911 1.000 18.77296 ? 138 LEU A CG  1 
ATOM   879  C CD1 . LEU A 1 111 ? -1.26655  8.60534   27.93766 1.000 21.51109 ? 138 LEU A CD1 1 
ATOM   880  C CD2 . LEU A 1 111 ? -0.83240  10.31521  29.79659 1.000 21.78577 ? 138 LEU A CD2 1 
ATOM   881  N N   . ILE A 1 112 ? 0.47060   5.71079   32.22550 1.000 15.34010 ? 139 ILE A N   1 
ATOM   882  C CA  . ILE A 1 112 ? 0.25047   4.56436   33.11512 1.000 15.52570 ? 139 ILE A CA  1 
ATOM   883  C C   . ILE A 1 112 ? 0.62785   4.92975   34.54246 1.000 16.21838 ? 139 ILE A C   1 
ATOM   884  O O   . ILE A 1 112 ? -0.11230  4.63835   35.50450 1.000 17.37257 ? 139 ILE A O   1 
ATOM   885  C CB  . ILE A 1 112 ? 1.03759   3.34156   32.59424 1.000 12.91573 ? 139 ILE A CB  1 
ATOM   886  C CG1 . ILE A 1 112 ? 0.47440   2.89552   31.22854 1.000 13.26832 ? 139 ILE A CG1 1 
ATOM   887  C CG2 . ILE A 1 112 ? 1.01235   2.16492   33.65706 1.000 18.10331 ? 139 ILE A CG2 1 
ATOM   888  C CD1 . ILE A 1 112 ? 1.30365   1.76997   30.56229 1.000 15.50113 ? 139 ILE A CD1 1 
ATOM   889  N N   . ALA A 1 113 ? 1.75868   5.62572   34.72198 1.000 16.89240 ? 140 ALA A N   1 
ATOM   890  C CA  . ALA A 1 113 ? 2.15577   6.02835   36.07332 1.000 18.74234 ? 140 ALA A CA  1 
ATOM   891  C C   . ALA A 1 113 ? 1.12707   6.95351   36.72189 1.000 16.01161 ? 140 ALA A C   1 
ATOM   892  O O   . ALA A 1 113 ? 0.86302   6.85942   37.93169 1.000 17.92143 ? 140 ALA A O   1 
ATOM   893  C CB  . ALA A 1 113 ? 3.53822   6.69516   36.02900 1.000 21.83308 ? 140 ALA A CB  1 
ATOM   894  N N   . GLN A 1 114 ? 0.58241   7.89319   35.95194 1.000 17.25438 ? 141 GLN A N   1 
ATOM   895  C CA  . GLN A 1 114 ? -0.42955  8.80160   36.47281 1.000 18.27827 ? 141 GLN A CA  1 
ATOM   896  C C   . GLN A 1 114 ? -1.65263  8.05456   36.99327 1.000 19.03207 ? 141 GLN A C   1 
ATOM   897  O O   . GLN A 1 114 ? -2.29080  8.49793   37.98313 1.000 21.27304 ? 141 GLN A O   1 
ATOM   898  C CB  . GLN A 1 114 ? -0.81989  9.77604   35.35505 1.000 19.39849 ? 141 GLN A CB  1 
ATOM   899  C CG  . GLN A 1 114 ? -2.09504  10.56900  35.67926 1.000 24.48183 ? 141 GLN A CG  1 
ATOM   900  C CD  . GLN A 1 114 ? -1.93887  11.52756  36.85308 1.000 29.59422 ? 141 GLN A CD  1 
ATOM   901  O OE1 . GLN A 1 114 ? -0.82869  11.95194  37.20646 1.000 28.52298 ? 141 GLN A OE1 1 
ATOM   902  N NE2 . GLN A 1 114 ? -3.06196  11.86347  37.47607 1.000 29.68684 ? 141 GLN A NE2 1 
ATOM   903  N N   . LEU A 1 115 ? -1.98449  6.93794   36.35799 1.000 18.90428 ? 142 LEU A N   1 
ATOM   904  C CA  . LEU A 1 115 ? -3.13303  6.12686   36.73248 1.000 15.32590 ? 142 LEU A CA  1 
ATOM   905  C C   . LEU A 1 115 ? -2.77943  5.09212   37.80405 1.000 19.82375 ? 142 LEU A C   1 
ATOM   906  O O   . LEU A 1 115 ? -3.64008  4.29948   38.22772 1.000 19.64075 ? 142 LEU A O   1 
ATOM   907  C CB  . LEU A 1 115 ? -3.65401  5.41624   35.49487 1.000 14.32586 ? 142 LEU A CB  1 
ATOM   908  C CG  . LEU A 1 115 ? -4.14014  6.44531   34.43822 1.000 19.20104 ? 142 LEU A CG  1 
ATOM   909  C CD1 . LEU A 1 115 ? -4.29000  5.75064   33.09418 1.000 19.59060 ? 142 LEU A CD1 1 
ATOM   910  C CD2 . LEU A 1 115 ? -5.44812  7.06435   34.89332 1.000 19.79904 ? 142 LEU A CD2 1 
ATOM   911  N N   . GLY A 1 116 ? -1.54831  5.05756   38.26464 1.000 14.02037 ? 143 GLY A N   1 
ATOM   912  C CA  . GLY A 1 116 ? -1.23382  4.10865   39.33858 1.000 15.58418 ? 143 GLY A CA  1 
ATOM   913  C C   . GLY A 1 116 ? -0.81345  2.71958   38.88871 1.000 16.21617 ? 143 GLY A C   1 
ATOM   914  O O   . GLY A 1 116 ? -0.85020  1.78611   39.69964 1.000 18.58343 ? 143 GLY A O   1 
ATOM   915  N N   . GLY A 1 117 ? -0.36478  2.56107   37.64376 1.000 14.96484 ? 144 GLY A N   1 
ATOM   916  C CA  . GLY A 1 117 ? 0.09260   1.27585   37.15073 1.000 12.52514 ? 144 GLY A CA  1 
ATOM   917  C C   . GLY A 1 117 ? -0.88811  0.72566   36.13015 1.000 15.56687 ? 144 GLY A C   1 
ATOM   918  O O   . GLY A 1 117 ? -1.99071  1.25472   35.93285 1.000 16.33125 ? 144 GLY A O   1 
ATOM   919  N N   . PRO A 1 118 ? -0.51526  -0.37034  35.47459 1.000 13.44186 ? 145 PRO A N   1 
ATOM   920  C CA  . PRO A 1 118 ? -1.44412  -0.96629  34.48669 1.000 12.60044 ? 145 PRO A CA  1 
ATOM   921  C C   . PRO A 1 118 ? -2.77309  -1.32738  35.10431 1.000 18.38015 ? 145 PRO A C   1 
ATOM   922  O O   . PRO A 1 118 ? -3.79525  -1.27482  34.40286 1.000 17.74725 ? 145 PRO A O   1 
ATOM   923  C CB  . PRO A 1 118 ? -0.70471  -2.22723  33.97328 1.000 17.49223 ? 145 PRO A CB  1 
ATOM   924  C CG  . PRO A 1 118 ? 0.70167   -2.08126  34.41853 1.000 21.28906 ? 145 PRO A CG  1 
ATOM   925  C CD  . PRO A 1 118 ? 0.78249   -1.06907  35.55637 1.000 16.12968 ? 145 PRO A CD  1 
ATOM   926  N N   . GLY A 1 119 ? -2.80156  -1.64603  36.41194 1.000 15.46049 ? 146 GLY A N   1 
ATOM   927  C CA  . GLY A 1 119 ? -4.07356  -1.96814  37.04153 1.000 15.32804 ? 146 GLY A CA  1 
ATOM   928  C C   . GLY A 1 119 ? -5.03094  -0.79483  37.02191 1.000 19.29514 ? 146 GLY A C   1 
ATOM   929  O O   . GLY A 1 119 ? -6.25587  -0.99138  37.04144 1.000 19.42145 ? 146 GLY A O   1 
ATOM   930  N N   . GLY A 1 120 ? -4.49568  0.43862   36.99167 1.000 16.40040 ? 147 GLY A N   1 
ATOM   931  C CA  . GLY A 1 120 ? -5.34427  1.61394   36.93570 1.000 15.87296 ? 147 GLY A CA  1 
ATOM   932  C C   . GLY A 1 120 ? -5.94501  1.83449   35.55466 1.000 18.38158 ? 147 GLY A C   1 
ATOM   933  O O   . GLY A 1 120 ? -7.02608  2.41676   35.44097 1.000 21.68607 ? 147 GLY A O   1 
ATOM   934  N N   . VAL A 1 121 ? -5.24779  1.40670   34.49770 1.000 15.18259 ? 148 VAL A N   1 
ATOM   935  C CA  . VAL A 1 121 ? -5.81584  1.50672   33.15039 1.000 13.62242 ? 148 VAL A CA  1 
ATOM   936  C C   . VAL A 1 121 ? -6.91136  0.47118   32.98909 1.000 18.25384 ? 148 VAL A C   1 
ATOM   937  O O   . VAL A 1 121 ? -8.01536  0.77590   32.51810 1.000 19.10891 ? 148 VAL A O   1 
ATOM   938  C CB  . VAL A 1 121 ? -4.70406  1.32838   32.10166 1.000 14.84590 ? 148 VAL A CB  1 
ATOM   939  C CG1 . VAL A 1 121 ? -5.28741  1.50750   30.67451 1.000 17.39761 ? 148 VAL A CG1 1 
ATOM   940  C CG2 . VAL A 1 121 ? -3.57071  2.32545   32.36998 1.000 18.46899 ? 148 VAL A CG2 1 
ATOM   941  N N   . THR A 1 122 ? -6.64501  -0.75569  33.46751 1.000 16.44150 ? 149 THR A N   1 
ATOM   942  C CA  . THR A 1 122 ? -7.65187  -1.80739  33.39577 1.000 16.22243 ? 149 THR A CA  1 
ATOM   943  C C   . THR A 1 122 ? -8.88672  -1.41545  34.17596 1.000 19.46035 ? 149 THR A C   1 
ATOM   944  O O   . THR A 1 122 ? -10.01394 -1.68556  33.74764 1.000 17.74913 ? 149 THR A O   1 
ATOM   945  C CB  . THR A 1 122 ? -7.05075  -3.12126  33.91101 1.000 18.90489 ? 149 THR A CB  1 
ATOM   946  O OG1 . THR A 1 122 ? -5.92417  -3.46840  33.09214 1.000 17.17928 ? 149 THR A OG1 1 
ATOM   947  C CG2 . THR A 1 122 ? -8.06996  -4.25781  33.80783 1.000 22.71352 ? 149 THR A CG2 1 
ATOM   948  N N   . ALA A 1 123 ? -8.69658  -0.77055  35.33893 1.000 19.05756 ? 150 ALA A N   1 
ATOM   949  C CA  . ALA A 1 123 ? -9.82889  -0.36368  36.16406 1.000 18.44984 ? 150 ALA A CA  1 
ATOM   950  C C   . ALA A 1 123 ? -10.77248 0.54757   35.41293 1.000 19.73563 ? 150 ALA A C   1 
ATOM   951  O O   . ALA A 1 123 ? -11.99338 0.47731   35.58811 1.000 20.56572 ? 150 ALA A O   1 
ATOM   952  C CB  . ALA A 1 123 ? -9.30907  0.36372   37.39829 1.000 22.41116 ? 150 ALA A CB  1 
ATOM   953  N N   . PHE A 1 124 ? -10.21019 1.45988   34.63361 1.000 20.09591 ? 151 PHE A N   1 
ATOM   954  C CA  . PHE A 1 124 ? -11.03896 2.37573   33.86714 1.000 19.66818 ? 151 PHE A CA  1 
ATOM   955  C C   . PHE A 1 124 ? -11.87944 1.61859   32.84739 1.000 20.63896 ? 151 PHE A C   1 
ATOM   956  O O   . PHE A 1 124 ? -13.08358 1.88692   32.69599 1.000 21.37950 ? 151 PHE A O   1 
ATOM   957  C CB  . PHE A 1 124 ? -10.16918 3.42716   33.18289 1.000 18.27761 ? 151 PHE A CB  1 
ATOM   958  C CG  . PHE A 1 124 ? -10.96391 4.32064   32.25906 1.000 22.45727 ? 151 PHE A CG  1 
ATOM   959  C CD1 . PHE A 1 124 ? -11.87327 5.23250   32.77236 1.000 25.39762 ? 151 PHE A CD1 1 
ATOM   960  C CD2 . PHE A 1 124 ? -10.80731 4.22595   30.88813 1.000 25.64822 ? 151 PHE A CD2 1 
ATOM   961  C CE1 . PHE A 1 124 ? -12.61825 6.04947   31.93805 1.000 27.28927 ? 151 PHE A CE1 1 
ATOM   962  C CE2 . PHE A 1 124 ? -11.53751 5.04043   30.03547 1.000 25.68136 ? 151 PHE A CE2 1 
ATOM   963  C CZ  . PHE A 1 124 ? -12.43697 5.94739   30.55921 1.000 28.07386 ? 151 PHE A CZ  1 
ATOM   964  N N   . ALA A 1 125 ? -11.27475 0.64683   32.16868 1.000 19.03582 ? 152 ALA A N   1 
ATOM   965  C CA  . ALA A 1 125 ? -12.05207 -0.18696  31.25180 1.000 20.98032 ? 152 ALA A CA  1 
ATOM   966  C C   . ALA A 1 125 ? -13.22974 -0.83014  31.97464 1.000 22.61642 ? 152 ALA A C   1 
ATOM   967  O O   . ALA A 1 125 ? -14.36471 -0.81032  31.47695 1.000 21.58296 ? 152 ALA A O   1 
ATOM   968  C CB  . ALA A 1 125 ? -11.14648 -1.25718  30.62441 1.000 20.22540 ? 152 ALA A CB  1 
ATOM   969  N N   . ARG A 1 126 ? -12.98024 -1.38399  33.17431 1.000 21.11143 ? 153 ARG A N   1 
ATOM   970  C CA  . ARG A 1 126 ? -14.05838 -2.03703  33.90643 1.000 24.70273 ? 153 ARG A CA  1 
ATOM   971  C C   . ARG A 1 126 ? -15.13549 -1.03351  34.28592 1.000 26.28319 ? 153 ARG A C   1 
ATOM   972  O O   . ARG A 1 126 ? -16.33737 -1.34517  34.25993 1.000 27.42530 ? 153 ARG A O   1 
ATOM   973  C CB  . ARG A 1 126 ? -13.50142 -2.71959  35.15882 1.000 23.46616 ? 153 ARG A CB  1 
ATOM   974  C CG  . ARG A 1 126 ? -12.53087 -3.85697  34.88892 1.000 19.54675 ? 153 ARG A CG  1 
ATOM   975  C CD  . ARG A 1 126 ? -13.15972 -5.07636  34.27171 1.000 20.65412 ? 153 ARG A CD  1 
ATOM   976  N NE  . ARG A 1 126 ? -12.10115 -6.06680  34.08151 1.000 25.72503 ? 153 ARG A NE  1 
ATOM   977  C CZ  . ARG A 1 126 ? -11.33367 -6.15340  32.99560 1.000 23.73338 ? 153 ARG A CZ  1 
ATOM   978  N NH1 . ARG A 1 126 ? -11.52643 -5.35888  31.93976 1.000 21.64444 ? 153 ARG A NH1 1 
ATOM   979  N NH2 . ARG A 1 126 ? -10.32413 -7.03451  32.98441 1.000 21.36854 ? 153 ARG A NH2 1 
ATOM   980  N N   . ALA A 1 127 ? -14.72658 0.19605   34.60080 1.000 23.68588 ? 154 ALA A N   1 
ATOM   981  C CA  . ALA A 1 127 ? -15.67257 1.21957   35.04499 1.000 27.19019 ? 154 ALA A CA  1 
ATOM   982  C C   . ALA A 1 127 ? -16.60829 1.65609   33.92896 1.000 30.43957 ? 154 ALA A C   1 
ATOM   983  O O   . ALA A 1 127 ? -17.71942 2.10344   34.21562 1.000 30.08738 ? 154 ALA A O   1 
ATOM   984  C CB  . ALA A 1 127 ? -14.92206 2.43629   35.58591 1.000 32.51772 ? 154 ALA A CB  1 
ATOM   985  N N   . ILE A 1 128 ? -16.19565 1.54027   32.66874 1.000 29.03840 ? 155 ILE A N   1 
ATOM   986  C CA  . ILE A 1 128 ? -17.08779 1.86178   31.55441 1.000 27.51776 ? 155 ILE A CA  1 
ATOM   987  C C   . ILE A 1 128 ? -17.70148 0.61228   30.91947 1.000 32.77595 ? 155 ILE A C   1 
ATOM   988  O O   . ILE A 1 128 ? -18.27022 0.70217   29.82286 1.000 38.69899 ? 155 ILE A O   1 
ATOM   989  C CB  . ILE A 1 128 ? -16.39137 2.73316   30.50066 1.000 28.76247 ? 155 ILE A CB  1 
ATOM   990  C CG1 . ILE A 1 128 ? -15.20932 1.99754   29.87187 1.000 26.90389 ? 155 ILE A CG1 1 
ATOM   991  C CG2 . ILE A 1 128 ? -15.94093 4.04263   31.13141 1.000 41.52060 ? 155 ILE A CG2 1 
ATOM   992  C CD1 . ILE A 1 128 ? -14.60380 2.72716   28.69669 1.000 29.33289 ? 155 ILE A CD1 1 
ATOM   993  N N   . GLY A 1 129 ? -17.62274 -0.54461  31.58257 1.000 26.35009 ? 156 GLY A N   1 
ATOM   994  C CA  . GLY A 1 129 ? -18.33699 -1.72951  31.12822 1.000 34.18124 ? 156 GLY A CA  1 
ATOM   995  C C   . GLY A 1 129 ? -17.56081 -2.68168  30.23756 1.000 32.58416 ? 156 GLY A C   1 
ATOM   996  O O   . GLY A 1 129 ? -18.15441 -3.60299  29.66040 1.000 34.02920 ? 156 GLY A O   1 
ATOM   997  N N   . ASP A 1 130 ? -16.26456 -2.50187  30.10393 1.000 22.71069 ? 157 ASP A N   1 
ATOM   998  C CA  . ASP A 1 130 ? -15.43002 -3.38520  29.30775 1.000 21.02502 ? 157 ASP A CA  1 
ATOM   999  C C   . ASP A 1 130 ? -14.79818 -4.40522  30.25344 1.000 23.31804 ? 157 ASP A C   1 
ATOM   1000 O O   . ASP A 1 130 ? -13.90022 -4.07196  31.03422 1.000 23.43169 ? 157 ASP A O   1 
ATOM   1001 C CB  . ASP A 1 130 ? -14.38206 -2.56105  28.55413 1.000 21.78082 ? 157 ASP A CB  1 
ATOM   1002 C CG  . ASP A 1 130 ? -13.56903 -3.38224  27.57949 1.000 25.31502 ? 157 ASP A CG  1 
ATOM   1003 O OD1 . ASP A 1 130 ? -13.38899 -4.59321  27.79361 1.000 22.27018 ? 157 ASP A OD1 1 
ATOM   1004 O OD2 . ASP A 1 130 ? -13.05935 -2.78351  26.60339 1.000 24.67981 ? 157 ASP A OD2 1 
ATOM   1005 N N   . GLU A 1 131 ? -15.30575 -5.63513  30.22144 1.000 24.92459 ? 158 GLU A N   1 
ATOM   1006 C CA  . GLU A 1 131 ? -14.79857 -6.70598  31.06634 1.000 26.81658 ? 158 GLU A CA  1 
ATOM   1007 C C   . GLU A 1 131 ? -13.75123 -7.53944  30.36243 1.000 25.77722 ? 158 GLU A C   1 
ATOM   1008 O O   . GLU A 1 131 ? -13.26977 -8.52004  30.92827 1.000 27.22529 ? 158 GLU A O   1 
ATOM   1009 C CB  . GLU A 1 131 ? -15.94125 -7.60340  31.53082 1.000 30.21419 ? 158 GLU A CB  1 
ATOM   1010 C CG  . GLU A 1 131 ? -16.77616 -6.96721  32.64048 1.000 45.97361 ? 158 GLU A CG  1 
ATOM   1011 C CD  . GLU A 1 131 ? -18.02486 -7.74990  32.94729 1.000 70.88182 ? 158 GLU A CD  1 
ATOM   1012 O OE1 . GLU A 1 131 ? -18.71496 -8.17167  31.99298 1.000 80.12201 ? 158 GLU A OE1 1 
ATOM   1013 O OE2 . GLU A 1 131 ? -18.31389 -7.94958  34.14393 1.000 80.20917 ? 158 GLU A OE2 1 
ATOM   1014 N N   . THR A 1 132 ? -13.35222 -7.14098  29.15294 1.000 20.76056 ? 159 THR A N   1 
ATOM   1015 C CA  . THR A 1 132 ? -12.46773 -7.95590  28.33422 1.000 18.99273 ? 159 THR A CA  1 
ATOM   1016 C C   . THR A 1 132 ? -11.05319 -7.40167  28.27498 1.000 17.13198 ? 159 THR A C   1 
ATOM   1017 O O   . THR A 1 132 ? -10.05708 -8.14561  28.40260 1.000 18.63760 ? 159 THR A O   1 
ATOM   1018 C CB  . THR A 1 132 ? -13.08194 -8.02864  26.92915 1.000 19.67236 ? 159 THR A CB  1 
ATOM   1019 O OG1 . THR A 1 132 ? -14.42905 -8.51216  27.00560 1.000 24.22800 ? 159 THR A OG1 1 
ATOM   1020 C CG2 . THR A 1 132 ? -12.25224 -8.90663  25.98817 1.000 22.18508 ? 159 THR A CG2 1 
ATOM   1021 N N   . PHE A 1 133 ? -10.94947 -6.09193  28.10161 1.000 16.00294 ? 160 PHE A N   1 
ATOM   1022 C CA  . PHE A 1 133 ? -9.65700  -5.40490  28.08314 1.000 16.13739 ? 160 PHE A CA  1 
ATOM   1023 C C   . PHE A 1 133 ? -8.79791  -5.78019  29.27680 1.000 15.95608 ? 160 PHE A C   1 
ATOM   1024 O O   . PHE A 1 133 ? -9.26292  -5.71916  30.41782 1.000 17.14130 ? 160 PHE A O   1 
ATOM   1025 C CB  . PHE A 1 133 ? -9.92275  -3.89111  28.11037 1.000 17.91209 ? 160 PHE A CB  1 
ATOM   1026 C CG  . PHE A 1 133 ? -8.67338  -3.02941  28.14126 1.000 17.05408 ? 160 PHE A CG  1 
ATOM   1027 C CD1 . PHE A 1 133 ? -8.06380  -2.71721  29.33493 1.000 19.07482 ? 160 PHE A CD1 1 
ATOM   1028 C CD2 . PHE A 1 133 ? -8.15151  -2.48490  26.95188 1.000 18.17964 ? 160 PHE A CD2 1 
ATOM   1029 C CE1 . PHE A 1 133 ? -6.92574  -1.89067  29.38852 1.000 16.66136 ? 160 PHE A CE1 1 
ATOM   1030 C CE2 . PHE A 1 133 ? -6.99706  -1.63963  26.99298 1.000 15.20422 ? 160 PHE A CE2 1 
ATOM   1031 C CZ  . PHE A 1 133 ? -6.39541  -1.36570  28.22082 1.000 15.54095 ? 160 PHE A CZ  1 
ATOM   1032 N N   . ARG A 1 134 ? -7.50577  -6.08045  29.03878 1.000 14.72252 ? 161 ARG A N   1 
ATOM   1033 C CA  . ARG A 1 134 ? -6.60655  -6.18055  30.19294 1.000 15.10194 ? 161 ARG A CA  1 
ATOM   1034 C C   . ARG A 1 134 ? -5.27666  -5.58126  29.80476 1.000 14.58591 ? 161 ARG A C   1 
ATOM   1035 O O   . ARG A 1 134 ? -4.71124  -5.95608  28.78174 1.000 16.39833 ? 161 ARG A O   1 
ATOM   1036 C CB  . ARG A 1 134 ? -6.40263  -7.61953  30.71538 1.000 18.04583 ? 161 ARG A CB  1 
ATOM   1037 C CG  . ARG A 1 134 ? -6.05822  -8.64871  29.63868 1.000 17.88390 ? 161 ARG A CG  1 
ATOM   1038 C CD  . ARG A 1 134 ? -6.05989  -10.01950 30.26754 1.000 17.52039 ? 161 ARG A CD  1 
ATOM   1039 N NE  . ARG A 1 134 ? -4.90232  -10.12182 31.14875 1.000 18.79350 ? 161 ARG A NE  1 
ATOM   1040 C CZ  . ARG A 1 134 ? -4.62062  -11.19220 31.86953 1.000 23.85765 ? 161 ARG A CZ  1 
ATOM   1041 N NH1 . ARG A 1 134 ? -5.43037  -12.25365 31.87936 1.000 23.57000 ? 161 ARG A NH1 1 
ATOM   1042 N NH2 . ARG A 1 134 ? -3.51965  -11.19258 32.62423 1.000 26.02173 ? 161 ARG A NH2 1 
ATOM   1043 N N   . LEU A 1 135 ? -4.76224  -4.68605  30.63526 1.000 16.98124 ? 162 LEU A N   1 
ATOM   1044 C CA  . LEU A 1 135 ? -3.39715  -4.18632  30.47906 1.000 15.03261 ? 162 LEU A CA  1 
ATOM   1045 C C   . LEU A 1 135 ? -2.60626  -4.70076  31.66852 1.000 14.49228 ? 162 LEU A C   1 
ATOM   1046 O O   . LEU A 1 135 ? -3.03161  -4.54233  32.82446 1.000 17.14186 ? 162 LEU A O   1 
ATOM   1047 C CB  . LEU A 1 135 ? -3.34032  -2.65696  30.43705 1.000 16.96610 ? 162 LEU A CB  1 
ATOM   1048 C CG  . LEU A 1 135 ? -1.98207  -2.19015  29.94066 1.000 17.25928 ? 162 LEU A CG  1 
ATOM   1049 C CD1 . LEU A 1 135 ? -1.85465  -2.42696  28.45441 1.000 22.36578 ? 162 LEU A CD1 1 
ATOM   1050 C CD2 . LEU A 1 135 ? -1.86278  -0.67120  30.29567 1.000 22.27241 ? 162 LEU A CD2 1 
ATOM   1051 N N   . ASP A 1 136 ? -1.50587  -5.38886  31.38540 1.000 14.59560 ? 163 ASP A N   1 
ATOM   1052 C CA  . ASP A 1 136 ? -0.71635  -6.09494  32.37008 1.000 14.97019 ? 163 ASP A CA  1 
ATOM   1053 C C   . ASP A 1 136 ? 0.68919   -5.54409  32.50818 1.000 15.69746 ? 163 ASP A C   1 
ATOM   1054 O O   . ASP A 1 136 ? 1.27678   -5.64248  33.58902 1.000 16.66341 ? 163 ASP A O   1 
ATOM   1055 C CB  . ASP A 1 136 ? -0.59987  -7.57062  31.98832 1.000 14.84334 ? 163 ASP A CB  1 
ATOM   1056 C CG  . ASP A 1 136 ? -1.94108  -8.26814  32.07155 1.000 19.17895 ? 163 ASP A CG  1 
ATOM   1057 O OD1 . ASP A 1 136 ? -2.33128  -8.62632  33.21365 1.000 22.91845 ? 163 ASP A OD1 1 
ATOM   1058 O OD2 . ASP A 1 136 ? -2.60366  -8.33872  31.03877 1.000 17.56271 ? 163 ASP A OD2 1 
ATOM   1059 N N   . ARG A 1 137 ? 1.24077   -4.99292  31.43791 1.000 14.93523 ? 164 ARG A N   1 
ATOM   1060 C CA  . ARG A 1 137 ? 2.62644   -4.55955  31.43063 1.000 15.13991 ? 164 ARG A CA  1 
ATOM   1061 C C   . ARG A 1 137 ? 2.73168   -3.12355  30.92713 1.000 14.68528 ? 164 ARG A C   1 
ATOM   1062 O O   . ARG A 1 137 ? 1.77023   -2.56382  30.39829 1.000 18.65166 ? 164 ARG A O   1 
ATOM   1063 C CB  . ARG A 1 137 ? 3.47283   -5.48556  30.53326 1.000 16.30655 ? 164 ARG A CB  1 
ATOM   1064 C CG  . ARG A 1 137 ? 3.67428   -6.86587  31.18181 1.000 14.12592 ? 164 ARG A CG  1 
ATOM   1065 C CD  . ARG A 1 137 ? 4.31101   -7.83250  30.20490 1.000 15.11470 ? 164 ARG A CD  1 
ATOM   1066 N NE  . ARG A 1 137 ? 3.35935   -8.16753  29.15277 1.000 14.97008 ? 164 ARG A NE  1 
ATOM   1067 C CZ  . ARG A 1 137 ? 3.68528   -8.87986  28.07984 1.000 16.78085 ? 164 ARG A CZ  1 
ATOM   1068 N NH1 . ARG A 1 137 ? 4.87673   -9.47353  27.98648 1.000 18.94909 ? 164 ARG A NH1 1 
ATOM   1069 N NH2 . ARG A 1 137 ? 2.80917   -8.97964  27.07697 1.000 16.20285 ? 164 ARG A NH2 1 
ATOM   1070 N N   . THR A 1 138 ? 3.94005   -2.55245  31.09952 1.000 14.49394 ? 165 THR A N   1 
ATOM   1071 C CA  . THR A 1 138 ? 4.23900   -1.20910  30.57949 1.000 14.50401 ? 165 THR A CA  1 
ATOM   1072 C C   . THR A 1 138 ? 4.94248   -1.32493  29.23215 1.000 16.94726 ? 165 THR A C   1 
ATOM   1073 O O   . THR A 1 138 ? 5.17455   -2.41577  28.71623 1.000 17.96883 ? 165 THR A O   1 
ATOM   1074 C CB  . THR A 1 138 ? 5.11601   -0.44174  31.55775 1.000 16.79876 ? 165 THR A CB  1 
ATOM   1075 O OG1 . THR A 1 138 ? 6.33885   -1.17947  31.74635 1.000 20.58581 ? 165 THR A OG1 1 
ATOM   1076 C CG2 . THR A 1 138 ? 4.41269   -0.30431  32.94129 1.000 20.54192 ? 165 THR A CG2 1 
ATOM   1077 N N   . GLU A 1 139 ? 5.27722   -0.18895  28.65757 1.000 14.90699 ? 166 GLU A N   1 
ATOM   1078 C CA  . GLU A 1 139 ? 6.10406   -0.20444  27.44050 1.000 15.20842 ? 166 GLU A CA  1 
ATOM   1079 C C   . GLU A 1 139 ? 7.55836   -0.46487  27.79668 1.000 17.17586 ? 166 GLU A C   1 
ATOM   1080 O O   . GLU A 1 139 ? 8.07906   0.11320   28.75590 1.000 20.95996 ? 166 GLU A O   1 
ATOM   1081 C CB  . GLU A 1 139 ? 6.03555   1.15266   26.70829 1.000 18.45705 ? 166 GLU A CB  1 
ATOM   1082 C CG  . GLU A 1 139 ? 4.62965   1.47758   26.18949 1.000 16.51811 ? 166 GLU A CG  1 
ATOM   1083 C CD  . GLU A 1 139 ? 4.23965   0.67892   24.94464 1.000 21.65402 ? 166 GLU A CD  1 
ATOM   1084 O OE1 . GLU A 1 139 ? 5.01926   -0.16945  24.46225 1.000 21.15877 ? 166 GLU A OE1 1 
ATOM   1085 O OE2 . GLU A 1 139 ? 3.10742   0.87913   24.46763 1.000 21.61547 ? 166 GLU A OE2 1 
ATOM   1086 N N   . PRO A 1 140 ? 8.27298   -1.23187  26.98465 1.000 18.25640 ? 167 PRO A N   1 
ATOM   1087 C CA  . PRO A 1 140 ? 7.85996   -1.80140  25.70907 1.000 20.28089 ? 167 PRO A CA  1 
ATOM   1088 C C   . PRO A 1 140 ? 7.45839   -3.25472  25.80710 1.000 18.00175 ? 167 PRO A C   1 
ATOM   1089 O O   . PRO A 1 140 ? 7.14571   -3.85673  24.75028 1.000 20.69846 ? 167 PRO A O   1 
ATOM   1090 C CB  . PRO A 1 140 ? 9.13956   -1.62749  24.86328 1.000 23.18203 ? 167 PRO A CB  1 
ATOM   1091 C CG  . PRO A 1 140 ? 10.20057  -1.96955  25.84880 1.000 25.00963 ? 167 PRO A CG  1 
ATOM   1092 C CD  . PRO A 1 140 ? 9.74609   -1.31193  27.14574 1.000 23.11023 ? 167 PRO A CD  1 
ATOM   1093 N N   . THR A 1 141 ? 7.42927   -3.89664  26.98447 1.000 19.15716 ? 168 THR A N   1 
ATOM   1094 C CA  . THR A 1 141 ? 7.18841   -5.34275  26.98742 1.000 17.15936 ? 168 THR A CA  1 
ATOM   1095 C C   . THR A 1 141 ? 5.74601   -5.71657  26.68371 1.000 18.64252 ? 168 THR A C   1 
ATOM   1096 O O   . THR A 1 141 ? 5.47684   -6.89589  26.41957 1.000 17.31099 ? 168 THR A O   1 
ATOM   1097 C CB  . THR A 1 141 ? 7.61842   -5.99073  28.32553 1.000 20.39727 ? 168 THR A CB  1 
ATOM   1098 O OG1 . THR A 1 141 ? 6.92393   -5.40538  29.42827 1.000 21.52160 ? 168 THR A OG1 1 
ATOM   1099 C CG2 . THR A 1 141 ? 9.11678   -5.78157  28.54979 1.000 25.07905 ? 168 THR A CG2 1 
ATOM   1100 N N   . LEU A 1 142 ? 4.80111   -4.76737  26.69797 1.000 14.79065 ? 169 LEU A N   1 
ATOM   1101 C CA  . LEU A 1 142 ? 3.42240   -5.15656  26.41150 1.000 17.43203 ? 169 LEU A CA  1 
ATOM   1102 C C   . LEU A 1 142 ? 3.24139   -5.53694  24.95446 1.000 16.08133 ? 169 LEU A C   1 
ATOM   1103 O O   . LEU A 1 142 ? 2.16523   -6.01759  24.58179 1.000 19.08495 ? 169 LEU A O   1 
ATOM   1104 C CB  . LEU A 1 142 ? 2.43793   -4.03025  26.79080 1.000 13.98085 ? 169 LEU A CB  1 
ATOM   1105 C CG  . LEU A 1 142 ? 2.53494   -2.67421  26.08050 1.000 16.04422 ? 169 LEU A CG  1 
ATOM   1106 C CD1 . LEU A 1 142 ? 1.71991   -2.69287  24.82795 1.000 17.70715 ? 169 LEU A CD1 1 
ATOM   1107 C CD2 . LEU A 1 142 ? 1.96300   -1.55684  26.96577 1.000 18.11537 ? 169 LEU A CD2 1 
ATOM   1108 N N   . ASN A 1 143 ? 4.27485   -5.36691  24.13637 1.000 15.88434 ? 170 ASN A N   1 
ATOM   1109 C CA  . ASN A 1 143 ? 4.17922   -5.67237  22.70987 1.000 16.71503 ? 170 ASN A CA  1 
ATOM   1110 C C   . ASN A 1 143 ? 4.71498   -7.04677  22.32516 1.000 19.11935 ? 170 ASN A C   1 
ATOM   1111 O O   . ASN A 1 143 ? 4.89585   -7.30562  21.12679 1.000 17.94515 ? 170 ASN A O   1 
ATOM   1112 C CB  . ASN A 1 143 ? 4.93604   -4.63366  21.89553 1.000 25.08438 ? 170 ASN A CB  1 
ATOM   1113 C CG  . ASN A 1 143 ? 4.44247   -3.25978  22.16314 1.000 29.29772 ? 170 ASN A CG  1 
ATOM   1114 O OD1 . ASN A 1 143 ? 3.29679   -2.90688  21.82321 1.000 21.12632 ? 170 ASN A OD1 1 
ATOM   1115 N ND2 . ASN A 1 143 ? 5.28413   -2.46141  22.80695 1.000 24.10438 ? 170 ASN A ND2 1 
ATOM   1116 N N   . THR A 1 144 ? 4.99809   -7.92608  23.28422 1.000 14.95995 ? 171 THR A N   1 
ATOM   1117 C CA  . THR A 1 144 ? 5.63798   -9.19985  22.92794 1.000 15.69549 ? 171 THR A CA  1 
ATOM   1118 C C   . THR A 1 144 ? 4.71556   -10.08714 22.09170 1.000 17.10416 ? 171 THR A C   1 
ATOM   1119 O O   . THR A 1 144 ? 5.21117   -10.91550 21.30905 1.000 17.50067 ? 171 THR A O   1 
ATOM   1120 C CB  . THR A 1 144 ? 6.07893   -9.97428  24.16086 1.000 20.42297 ? 171 THR A CB  1 
ATOM   1121 O OG1 . THR A 1 144 ? 4.97092   -10.09611 25.06308 1.000 19.02362 ? 171 THR A OG1 1 
ATOM   1122 C CG2 . THR A 1 144 ? 7.25709   -9.25660  24.84667 1.000 20.17829 ? 171 THR A CG2 1 
ATOM   1123 N N   . ALA A 1 145 ? 3.38516   -9.93872  22.24812 1.000 14.66490 ? 172 ALA A N   1 
ATOM   1124 C CA  . ALA A 1 145 ? 2.42107   -10.56199 21.31160 1.000 17.20756 ? 172 ALA A CA  1 
ATOM   1125 C C   . ALA A 1 145 ? 2.60670   -12.07835 21.16275 1.000 17.26215 ? 172 ALA A C   1 
ATOM   1126 O O   . ALA A 1 145 ? 2.44899   -12.66001 20.08135 1.000 18.80692 ? 172 ALA A O   1 
ATOM   1127 C CB  . ALA A 1 145 ? 2.46892   -9.87187  19.92858 1.000 18.22852 ? 172 ALA A CB  1 
ATOM   1128 N N   . ILE A 1 146 ? 2.92964   -12.74993 22.26958 1.000 15.38007 ? 173 ILE A N   1 
ATOM   1129 C CA  A ILE A 1 146 ? 3.21526   -14.18569 22.22370 0.738 17.31383 ? 173 ILE A CA  1 
ATOM   1130 C CA  B ILE A 1 146 ? 3.21343   -14.19039 22.24281 0.262 17.44748 ? 173 ILE A CA  1 
ATOM   1131 C C   . ILE A 1 146 ? 1.91974   -14.95711 21.98934 1.000 20.12828 ? 173 ILE A C   1 
ATOM   1132 O O   . ILE A 1 146 ? 0.90916   -14.70082 22.66308 1.000 19.13795 ? 173 ILE A O   1 
ATOM   1133 C CB  A ILE A 1 146 ? 3.89497   -14.60649 23.52496 0.738 17.67890 ? 173 ILE A CB  1 
ATOM   1134 C CB  B ILE A 1 146 ? 3.85863   -14.61624 23.56216 0.262 17.81799 ? 173 ILE A CB  1 
ATOM   1135 C CG1 A ILE A 1 146 ? 5.29234   -13.96298 23.58185 0.738 22.37844 ? 173 ILE A CG1 1 
ATOM   1136 C CG1 B ILE A 1 146 ? 5.12467   -13.79244 23.80910 0.262 22.05070 ? 173 ILE A CG1 1 
ATOM   1137 C CG2 A ILE A 1 146 ? 3.92940   -16.13176 23.67731 0.738 21.69856 ? 173 ILE A CG2 1 
ATOM   1138 C CG2 B ILE A 1 146 ? 4.17907   -16.10473 23.56241 0.262 22.26554 ? 173 ILE A CG2 1 
ATOM   1139 C CD1 A ILE A 1 146 ? 5.84648   -13.81102 24.98280 0.738 25.41544 ? 173 ILE A CD1 1 
ATOM   1140 C CD1 B ILE A 1 146 ? 6.20200   -14.01753 22.78071 0.262 22.89032 ? 173 ILE A CD1 1 
ATOM   1141 N N   . PRO A 1 147 ? 1.89095   -15.89978 21.03959 1.000 19.79173 ? 174 PRO A N   1 
ATOM   1142 C CA  . PRO A 1 147 ? 0.65082   -16.63855 20.76241 1.000 23.20423 ? 174 PRO A CA  1 
ATOM   1143 C C   . PRO A 1 147 ? 0.12439   -17.32267 22.01395 1.000 24.97919 ? 174 PRO A C   1 
ATOM   1144 O O   . PRO A 1 147 ? 0.86678   -18.01198 22.71087 1.000 23.24417 ? 174 PRO A O   1 
ATOM   1145 C CB  . PRO A 1 147 ? 1.07981   -17.66862 19.71347 1.000 26.83946 ? 174 PRO A CB  1 
ATOM   1146 C CG  . PRO A 1 147 ? 2.36957   -17.14410 19.13197 1.000 28.87609 ? 174 PRO A CG  1 
ATOM   1147 C CD  . PRO A 1 147 ? 3.01203   -16.26508 20.15273 1.000 22.90280 ? 174 PRO A CD  1 
ATOM   1148 N N   . GLY A 1 148 ? -1.16860  -17.12484 22.30505 1.000 20.71391 ? 175 GLY A N   1 
ATOM   1149 C CA  . GLY A 1 148 ? -1.79707  -17.75658 23.45528 1.000 25.91525 ? 175 GLY A CA  1 
ATOM   1150 C C   . GLY A 1 148 ? -1.70106  -16.98037 24.76660 1.000 24.99251 ? 175 GLY A C   1 
ATOM   1151 O O   . GLY A 1 148 ? -2.42257  -17.30418 25.72004 1.000 24.89537 ? 175 GLY A O   1 
ATOM   1152 N N   . ASP A 1 149 ? -0.80568  -16.02107 24.85982 1.000 20.88802 ? 176 ASP A N   1 
ATOM   1153 C CA  . ASP A 1 149 ? -0.59136  -15.25281 26.08561 1.000 20.31258 ? 176 ASP A CA  1 
ATOM   1154 C C   . ASP A 1 149 ? -1.75420  -14.28555 26.27468 1.000 19.71436 ? 176 ASP A C   1 
ATOM   1155 O O   . ASP A 1 149 ? -1.99453  -13.46121 25.39547 1.000 19.83810 ? 176 ASP A O   1 
ATOM   1156 C CB  . ASP A 1 149 ? 0.70654   -14.47314 25.95866 1.000 18.85563 ? 176 ASP A CB  1 
ATOM   1157 C CG  . ASP A 1 149 ? 1.10577   -13.74045 27.23497 1.000 20.56781 ? 176 ASP A CG  1 
ATOM   1158 O OD1 . ASP A 1 149 ? 0.34526   -13.75560 28.25008 1.000 21.20009 ? 176 ASP A OD1 1 
ATOM   1159 O OD2 . ASP A 1 149 ? 2.21135   -13.15952 27.19566 1.000 20.83848 ? 176 ASP A OD2 1 
ATOM   1160 N N   . PRO A 1 150 ? -2.50811  -14.34485 27.37481 1.000 19.84622 ? 177 PRO A N   1 
ATOM   1161 C CA  . PRO A 1 150 ? -3.63532  -13.40795 27.51644 1.000 18.71160 ? 177 PRO A CA  1 
ATOM   1162 C C   . PRO A 1 150 ? -3.22186  -12.00788 27.94157 1.000 15.14332 ? 177 PRO A C   1 
ATOM   1163 O O   . PRO A 1 150 ? -4.06992  -11.10205 27.91328 1.000 16.35576 ? 177 PRO A O   1 
ATOM   1164 C CB  . PRO A 1 150 ? -4.50852  -14.07577 28.60485 1.000 22.99379 ? 177 PRO A CB  1 
ATOM   1165 C CG  . PRO A 1 150 ? -3.55764  -14.84553 29.38234 1.000 24.93233 ? 177 PRO A CG  1 
ATOM   1166 C CD  . PRO A 1 150 ? -2.54724  -15.40421 28.40566 1.000 24.44542 ? 177 PRO A CD  1 
ATOM   1167 N N   . ARG A 1 151 ? -1.96695  -11.78540 28.33791 1.000 15.23416 ? 178 ARG A N   1 
ATOM   1168 C CA  . ARG A 1 151 ? -1.58563  -10.45260 28.82012 1.000 13.66932 ? 178 ARG A CA  1 
ATOM   1169 C C   . ARG A 1 151 ? -1.73759  -9.39422  27.72959 1.000 13.13180 ? 178 ARG A C   1 
ATOM   1170 O O   . ARG A 1 151 ? -1.41964  -9.63630  26.55683 1.000 14.30389 ? 178 ARG A O   1 
ATOM   1171 C CB  . ARG A 1 151 ? -0.14240  -10.46002 29.30796 1.000 15.58805 ? 178 ARG A CB  1 
ATOM   1172 C CG  . ARG A 1 151 ? 0.05111   -11.30164 30.58057 1.000 17.46590 ? 178 ARG A CG  1 
ATOM   1173 C CD  . ARG A 1 151 ? 1.54817   -11.37807 30.98965 1.000 19.80972 ? 178 ARG A CD  1 
ATOM   1174 N NE  . ARG A 1 151 ? 2.35492   -12.08948 30.00651 1.000 22.75593 ? 178 ARG A NE  1 
ATOM   1175 C CZ  . ARG A 1 151 ? 3.67825   -12.19831 30.01049 1.000 27.49906 ? 178 ARG A CZ  1 
ATOM   1176 N NH1 . ARG A 1 151 ? 4.42397   -11.67190 30.98570 1.000 22.71186 ? 178 ARG A NH1 1 
ATOM   1177 N NH2 . ARG A 1 151 ? 4.27593   -12.83937 28.99859 1.000 23.60803 ? 178 ARG A NH2 1 
ATOM   1178 N N   . ASP A 1 152 ? -2.25590  -8.21140  28.10621 1.000 12.46524 ? 179 ASP A N   1 
ATOM   1179 C CA  . ASP A 1 152 ? -2.26656  -7.05165  27.19019 1.000 11.44588 ? 179 ASP A CA  1 
ATOM   1180 C C   . ASP A 1 152 ? -3.06780  -7.34328  25.92124 1.000 13.46858 ? 179 ASP A C   1 
ATOM   1181 O O   . ASP A 1 152 ? -2.68184  -6.94830  24.80536 1.000 14.71433 ? 179 ASP A O   1 
ATOM   1182 C CB  . ASP A 1 152 ? -0.82218  -6.65253  26.85518 1.000 12.81035 ? 179 ASP A CB  1 
ATOM   1183 C CG  . ASP A 1 152 ? -0.00300  -6.48536  28.13704 1.000 15.58696 ? 179 ASP A CG  1 
ATOM   1184 O OD1 . ASP A 1 152 ? -0.39986  -5.61550  28.91774 1.000 15.65917 ? 179 ASP A OD1 1 
ATOM   1185 O OD2 . ASP A 1 152 ? 0.97513   -7.19555  28.33931 1.000 16.83685 ? 179 ASP A OD2 1 
ATOM   1186 N N   . THR A 1 153 ? -4.20805  -8.03271  26.08570 1.000 14.41476 ? 180 THR A N   1 
ATOM   1187 C CA  . THR A 1 153 ? -5.08265  -8.39670  24.97339 1.000 13.10106 ? 180 THR A CA  1 
ATOM   1188 C C   . THR A 1 153 ? -6.48770  -7.84123  25.17397 1.000 13.98046 ? 180 THR A C   1 
ATOM   1189 O O   . THR A 1 153 ? -6.89852  -7.48260  26.29296 1.000 15.45890 ? 180 THR A O   1 
ATOM   1190 C CB  . THR A 1 153 ? -5.22733  -9.90014  24.79593 1.000 13.81061 ? 180 THR A CB  1 
ATOM   1191 O OG1 . THR A 1 153 ? -5.78234  -10.48269 25.98753 1.000 16.04488 ? 180 THR A OG1 1 
ATOM   1192 C CG2 . THR A 1 153 ? -3.86717  -10.52124 24.45007 1.000 15.03563 ? 180 THR A CG2 1 
ATOM   1193 N N   . THR A 1 154 ? -7.21624  -7.77638  24.04829 1.000 14.52130 ? 181 THR A N   1 
ATOM   1194 C CA  . THR A 1 154 ? -8.66163  -7.61688  24.11178 1.000 15.23942 ? 181 THR A CA  1 
ATOM   1195 C C   . THR A 1 154 ? -9.22685  -8.33859  22.89957 1.000 15.11761 ? 181 THR A C   1 
ATOM   1196 O O   . THR A 1 154 ? -8.48602  -8.97896  22.14837 1.000 16.87037 ? 181 THR A O   1 
ATOM   1197 C CB  . THR A 1 154 ? -9.03992  -6.13502  24.15704 1.000 16.14689 ? 181 THR A CB  1 
ATOM   1198 O OG1 . THR A 1 154 ? -10.41563 -6.02946  24.55105 1.000 17.76164 ? 181 THR A OG1 1 
ATOM   1199 C CG2 . THR A 1 154 ? -8.78400  -5.43547  22.77455 1.000 16.21425 ? 181 THR A CG2 1 
ATOM   1200 N N   . THR A 1 155 ? -10.54590 -8.29229  22.73891 1.000 17.09891 ? 182 THR A N   1 
ATOM   1201 C CA  . THR A 1 155 ? -11.11664 -8.85661  21.53029 1.000 16.90925 ? 182 THR A CA  1 
ATOM   1202 C C   . THR A 1 155 ? -11.61410 -7.74232  20.60116 1.000 15.69870 ? 182 THR A C   1 
ATOM   1203 O O   . THR A 1 155 ? -11.95674 -6.64349  21.06791 1.000 17.51049 ? 182 THR A O   1 
ATOM   1204 C CB  . THR A 1 155 ? -12.30941 -9.76778  21.87390 1.000 20.42714 ? 182 THR A CB  1 
ATOM   1205 O OG1 . THR A 1 155 ? -13.38698 -8.96350  22.39696 1.000 19.06683 ? 182 THR A OG1 1 
ATOM   1206 C CG2 . THR A 1 155 ? -11.89670 -10.87877 22.88909 1.000 19.12610 ? 182 THR A CG2 1 
ATOM   1207 N N   . PRO A 1 156 ? -11.80813 -8.03443  19.32238 1.000 17.65380 ? 183 PRO A N   1 
ATOM   1208 C CA  . PRO A 1 156 ? -12.33162 -6.97820  18.42854 1.000 17.66825 ? 183 PRO A CA  1 
ATOM   1209 C C   . PRO A 1 156 ? -13.68839 -6.46480  18.86469 1.000 21.53604 ? 183 PRO A C   1 
ATOM   1210 O O   . PRO A 1 156 ? -13.92228 -5.25080  18.84165 1.000 20.24949 ? 183 PRO A O   1 
ATOM   1211 C CB  . PRO A 1 156 ? -12.39949 -7.67576  17.06626 1.000 19.15621 ? 183 PRO A CB  1 
ATOM   1212 C CG  . PRO A 1 156 ? -11.24518 -8.72726  17.12087 1.000 18.22577 ? 183 PRO A CG  1 
ATOM   1213 C CD  . PRO A 1 156 ? -11.35783 -9.24012  18.57567 1.000 17.10024 ? 183 PRO A CD  1 
ATOM   1214 N N   . ARG A 1 157 ? -14.58608 -7.35372  19.29323 1.000 19.80261 ? 184 ARG A N   1 
ATOM   1215 C CA  . ARG A 1 157 ? -15.91650 -6.91558  19.68761 1.000 22.44803 ? 184 ARG A CA  1 
ATOM   1216 C C   . ARG A 1 157 ? -15.83898 -5.95604  20.86249 1.000 26.74257 ? 184 ARG A C   1 
ATOM   1217 O O   . ARG A 1 157 ? -16.46572 -4.89140  20.84590 1.000 21.86790 ? 184 ARG A O   1 
ATOM   1218 C CB  . ARG A 1 157 ? -16.79779 -8.11870  20.02432 1.000 23.00710 ? 184 ARG A CB  1 
ATOM   1219 C CG  . ARG A 1 157 ? -18.21363 -7.71009  20.44078 1.000 33.49479 ? 184 ARG A CG  1 
ATOM   1220 C CD  . ARG A 1 157 ? -18.85265 -8.75114  21.33490 1.000 34.62886 ? 184 ARG A CD  1 
ATOM   1221 N NE  . ARG A 1 157 ? -19.06858 -10.03404 20.67616 1.000 37.29105 ? 184 ARG A NE  1 
ATOM   1222 C CZ  . ARG A 1 157 ? -20.18639 -10.38443 20.05482 1.000 49.83046 ? 184 ARG A CZ  1 
ATOM   1223 N NH1 . ARG A 1 157 ? -21.19720 -9.53514  19.90899 1.000 51.54889 ? 184 ARG A NH1 1 
ATOM   1224 N NH2 . ARG A 1 157 ? -20.29550 -11.61802 19.56501 1.000 47.94846 ? 184 ARG A NH2 1 
ATOM   1225 N N   . ALA A 1 158 ? -15.02669 -6.29135  21.86585 1.000 20.52578 ? 185 ALA A N   1 
ATOM   1226 C CA  . ALA A 1 158 ? -14.96380 -5.45603  23.06115 1.000 21.50828 ? 185 ALA A CA  1 
ATOM   1227 C C   . ALA A 1 158 ? -14.36339 -4.09468  22.74550 1.000 20.41888 ? 185 ALA A C   1 
ATOM   1228 O O   . ALA A 1 158 ? -14.87346 -3.05997  23.20820 1.000 21.48441 ? 185 ALA A O   1 
ATOM   1229 C CB  . ALA A 1 158 ? -14.16326 -6.15681  24.15890 1.000 23.45933 ? 185 ALA A CB  1 
ATOM   1230 N N   . MET A 1 159 ? -13.30871 -4.06762  21.93597 1.000 17.37411 ? 186 MET A N   1 
ATOM   1231 C CA  . MET A 1 159 ? -12.66313 -2.79745  21.64709 1.000 18.36135 ? 186 MET A CA  1 
ATOM   1232 C C   . MET A 1 159 ? -13.55294 -1.90782  20.78095 1.000 20.17146 ? 186 MET A C   1 
ATOM   1233 O O   . MET A 1 159 ? -13.54812 -0.67290  20.95139 1.000 21.55527 ? 186 MET A O   1 
ATOM   1234 C CB  . MET A 1 159 ? -11.30884 -3.02915  20.97017 1.000 18.92010 ? 186 MET A CB  1 
ATOM   1235 C CG  . MET A 1 159 ? -10.49109 -1.74582  20.83690 1.000 20.78535 ? 186 MET A CG  1 
ATOM   1236 S SD  . MET A 1 159 ? -10.08491 -1.10317  22.51970 1.000 24.46419 ? 186 MET A SD  1 
ATOM   1237 C CE  . MET A 1 159 ? -8.38539  -1.55587  22.72157 1.000 33.33303 ? 186 MET A CE  1 
ATOM   1238 N N   . ALA A 1 160 ? -14.32505 -2.50062  19.85913 1.000 20.65463 ? 187 ALA A N   1 
ATOM   1239 C CA  . ALA A 1 160 ? -15.22046 -1.68395  19.03916 1.000 19.63526 ? 187 ALA A CA  1 
ATOM   1240 C C   . ALA A 1 160 ? -16.28664 -1.04111  19.90221 1.000 21.20175 ? 187 ALA A C   1 
ATOM   1241 O O   . ALA A 1 160 ? -16.58036 0.14407   19.75493 1.000 24.32208 ? 187 ALA A O   1 
ATOM   1242 C CB  . ALA A 1 160 ? -15.85356 -2.51893  17.92506 1.000 23.28971 ? 187 ALA A CB  1 
ATOM   1243 N N   . GLN A 1 161 ? -16.83989 -1.79150  20.84894 1.000 21.80261 ? 188 GLN A N   1 
ATOM   1244 C CA  . GLN A 1 161 ? -17.87921 -1.22139  21.69385 1.000 26.22781 ? 188 GLN A CA  1 
ATOM   1245 C C   . GLN A 1 161 ? -17.30705 -0.13636  22.59640 1.000 22.84952 ? 188 GLN A C   1 
ATOM   1246 O O   . GLN A 1 161 ? -17.94487 0.90754   22.81681 1.000 27.23753 ? 188 GLN A O   1 
ATOM   1247 C CB  . GLN A 1 161 ? -18.51134 -2.33285  22.51431 1.000 28.15599 ? 188 GLN A CB  1 
ATOM   1248 C CG  . GLN A 1 161 ? -19.23775 -3.35596  21.64517 1.000 40.55631 ? 188 GLN A CG  1 
ATOM   1249 C CD  . GLN A 1 161 ? -19.68998 -4.57706  22.43249 1.000 67.16218 ? 188 GLN A CD  1 
ATOM   1250 O OE1 . GLN A 1 161 ? -19.08183 -4.94332  23.44817 1.000 68.70018 ? 188 GLN A OE1 1 
ATOM   1251 N NE2 . GLN A 1 161 ? -20.75857 -5.21725  21.96459 1.000 65.23805 ? 188 GLN A NE2 1 
ATOM   1252 N N   . THR A 1 162 ? -16.12151 -0.38412  23.15226 1.000 22.23595 ? 189 THR A N   1 
ATOM   1253 C CA  . THR A 1 162 ? -15.51624 0.60902   24.01911 1.000 25.96380 ? 189 THR A CA  1 
ATOM   1254 C C   . THR A 1 162 ? -15.12470 1.86137   23.23540 1.000 29.14505 ? 189 THR A C   1 
ATOM   1255 O O   . THR A 1 162 ? -15.36456 2.98363   23.69940 1.000 24.95425 ? 189 THR A O   1 
ATOM   1256 C CB  . THR A 1 162 ? -14.32476 -0.00334  24.73410 1.000 23.48628 ? 189 THR A CB  1 
ATOM   1257 O OG1 . THR A 1 162 ? -14.81005 -0.94984  25.70619 1.000 23.21804 ? 189 THR A OG1 1 
ATOM   1258 C CG2 . THR A 1 162 ? -13.58061 1.06813   25.49832 1.000 23.54633 ? 189 THR A CG2 1 
ATOM   1259 N N   . LEU A 1 163 ? -14.53841 1.70385   22.04099 1.000 19.55569 ? 190 LEU A N   1 
ATOM   1260 C CA  . LEU A 1 163 ? -14.18221 2.89497   21.26291 1.000 21.66080 ? 190 LEU A CA  1 
ATOM   1261 C C   . LEU A 1 163 ? -15.42824 3.69307   20.90865 1.000 23.97641 ? 190 LEU A C   1 
ATOM   1262 O O   . LEU A 1 163 ? -15.40567 4.93602   20.89464 1.000 24.82907 ? 190 LEU A O   1 
ATOM   1263 C CB  . LEU A 1 163 ? -13.41031 2.50959   19.99030 1.000 22.79229 ? 190 LEU A CB  1 
ATOM   1264 C CG  . LEU A 1 163 ? -12.81767 3.71866   19.23841 1.000 20.76174 ? 190 LEU A CG  1 
ATOM   1265 C CD1 . LEU A 1 163 ? -11.85821 4.52049   20.08987 1.000 24.33436 ? 190 LEU A CD1 1 
ATOM   1266 C CD2 . LEU A 1 163 ? -12.08953 3.19750   17.98913 1.000 24.24948 ? 190 LEU A CD2 1 
ATOM   1267 N N   . ARG A 1 164 ? -16.51964 3.00068   20.57013 1.000 22.77675 ? 191 ARG A N   1 
ATOM   1268 C CA  . ARG A 1 164 ? -17.78909 3.70052   20.35557 1.000 23.21230 ? 191 ARG A CA  1 
ATOM   1269 C C   . ARG A 1 164 ? -18.18861 4.52071   21.57571 1.000 26.90121 ? 191 ARG A C   1 
ATOM   1270 O O   . ARG A 1 164 ? -18.53561 5.70103   21.45190 1.000 29.37867 ? 191 ARG A O   1 
ATOM   1271 C CB  . ARG A 1 164 ? -18.90340 2.72509   20.03005 1.000 24.34937 ? 191 ARG A CB  1 
ATOM   1272 C CG  . ARG A 1 164 ? -20.22076 3.47971   19.62635 1.000 27.85288 ? 191 ARG A CG  1 
ATOM   1273 C CD  . ARG A 1 164 ? -21.42024 2.62340   19.86628 1.000 28.91622 ? 191 ARG A CD  1 
ATOM   1274 N NE  . ARG A 1 164 ? -22.61099 3.32052   19.40286 1.000 39.80226 ? 191 ARG A NE  1 
ATOM   1275 C CZ  . ARG A 1 164 ? -23.66932 2.72604   18.88527 1.000 51.16115 ? 191 ARG A CZ  1 
ATOM   1276 N NH1 . ARG A 1 164 ? -23.72703 1.40890   18.76021 1.000 51.29111 ? 191 ARG A NH1 1 
ATOM   1277 N NH2 . ARG A 1 164 ? -24.69039 3.47451   18.47513 1.000 46.06548 ? 191 ARG A NH2 1 
ATOM   1278 N N   A GLN A 1 165 ? -18.13566 3.91960   22.76635 0.544 26.43201 ? 192 GLN A N   1 
ATOM   1279 N N   B GLN A 1 165 ? -18.19693 3.89836   22.75631 0.456 26.46753 ? 192 GLN A N   1 
ATOM   1280 C CA  A GLN A 1 165 ? -18.60305 4.63405   23.95754 0.544 26.53439 ? 192 GLN A CA  1 
ATOM   1281 C CA  B GLN A 1 165 ? -18.58379 4.63229   23.96078 0.456 26.57063 ? 192 GLN A CA  1 
ATOM   1282 C C   A GLN A 1 165 ? -17.71606 5.83034   24.29587 0.544 28.62005 ? 192 GLN A C   1 
ATOM   1283 C C   B GLN A 1 165 ? -17.73133 5.88432   24.12835 0.456 28.24845 ? 192 GLN A C   1 
ATOM   1284 O O   A GLN A 1 165 ? -18.21447 6.84513   24.80948 0.544 27.92044 ? 192 GLN A O   1 
ATOM   1285 O O   B GLN A 1 165 ? -18.25711 6.99077   24.30937 0.456 28.38213 ? 192 GLN A O   1 
ATOM   1286 C CB  A GLN A 1 165 ? -18.68738 3.67431   25.14151 0.544 28.81838 ? 192 GLN A CB  1 
ATOM   1287 C CB  B GLN A 1 165 ? -18.46653 3.73211   25.19019 0.456 29.00448 ? 192 GLN A CB  1 
ATOM   1288 C CG  A GLN A 1 165 ? -19.87927 2.73332   25.07804 0.544 34.50048 ? 192 GLN A CG  1 
ATOM   1289 C CG  B GLN A 1 165 ? -19.73533 2.98086   25.54506 0.456 36.32123 ? 192 GLN A CG  1 
ATOM   1290 C CD  A GLN A 1 165 ? -21.19980 3.48057   25.06010 0.544 38.30396 ? 192 GLN A CD  1 
ATOM   1291 C CD  B GLN A 1 165 ? -19.59138 2.17112   26.81785 0.456 42.89602 ? 192 GLN A CD  1 
ATOM   1292 O OE1 A GLN A 1 165 ? -21.44233 4.35258   25.89364 0.544 44.55322 ? 192 GLN A OE1 1 
ATOM   1293 O OE1 B GLN A 1 165 ? -19.29491 0.97687   26.76896 0.456 42.71023 ? 192 GLN A OE1 1 
ATOM   1294 N NE2 A GLN A 1 165 ? -22.05453 3.15349   24.09432 0.544 42.19131 ? 192 GLN A NE2 1 
ATOM   1295 N NE2 B GLN A 1 165 ? -19.80197 2.81518   27.96896 0.456 39.36193 ? 192 GLN A NE2 1 
ATOM   1296 N N   . LEU A 1 166 ? -16.40642 5.72626   24.03628 1.000 23.47391 ? 193 LEU A N   1 
ATOM   1297 C CA  . LEU A 1 166 ? -15.48198 6.81983   24.33391 1.000 25.47854 ? 193 LEU A CA  1 
ATOM   1298 C C   . LEU A 1 166 ? -15.63342 8.00906   23.38773 1.000 26.75109 ? 193 LEU A C   1 
ATOM   1299 O O   . LEU A 1 166 ? -15.39895 9.15974   23.79012 1.000 26.85345 ? 193 LEU A O   1 
ATOM   1300 C CB  . LEU A 1 166 ? -14.05276 6.30658   24.23598 1.000 24.04324 ? 193 LEU A CB  1 
ATOM   1301 C CG  . LEU A 1 166 ? -13.69437 5.30772   25.31436 1.000 23.33371 ? 193 LEU A CG  1 
ATOM   1302 C CD1 . LEU A 1 166 ? -12.26519 4.89932   25.04338 1.000 22.68835 ? 193 LEU A CD1 1 
ATOM   1303 C CD2 . LEU A 1 166 ? -13.86265 5.94051   26.70311 1.000 26.29631 ? 193 LEU A CD2 1 
ATOM   1304 N N   . THR A 1 167 ? -15.91388 7.74963   22.11518 1.000 25.48691 ? 194 THR A N   1 
ATOM   1305 C CA  . THR A 1 167 ? -15.83033 8.78499   21.08594 1.000 24.86040 ? 194 THR A CA  1 
ATOM   1306 C C   . THR A 1 167 ? -17.18727 9.28273   20.63153 1.000 35.93096 ? 194 THR A C   1 
ATOM   1307 O O   . THR A 1 167 ? -17.34275 10.47470  20.36433 1.000 38.38371 ? 194 THR A O   1 
ATOM   1308 C CB  . THR A 1 167 ? -15.07388 8.26862   19.85103 1.000 28.76022 ? 194 THR A CB  1 
ATOM   1309 O OG1 . THR A 1 167 ? -15.78705 7.14778   19.32623 1.000 26.46137 ? 194 THR A OG1 1 
ATOM   1310 C CG2 . THR A 1 167 ? -13.67654 7.84573   20.21140 1.000 27.88766 ? 194 THR A CG2 1 
ATOM   1311 N N   . LEU A 1 168 ? -18.16047 8.39446   20.50184 1.000 26.78362 ? 195 LEU A N   1 
ATOM   1312 C CA  . LEU A 1 168 ? -19.48264 8.77782   20.04310 1.000 31.18053 ? 195 LEU A CA  1 
ATOM   1313 C C   . LEU A 1 168 ? -20.50736 8.75746   21.15129 1.000 33.39010 ? 195 LEU A C   1 
ATOM   1314 O O   . LEU A 1 168 ? -21.50633 9.48943   21.06481 1.000 37.61277 ? 195 LEU A O   1 
ATOM   1315 C CB  . LEU A 1 168 ? -19.94268 7.83742   18.92429 1.000 33.50094 ? 195 LEU A CB  1 
ATOM   1316 C CG  . LEU A 1 168 ? -19.00411 7.83331   17.72717 1.000 37.24730 ? 195 LEU A CG  1 
ATOM   1317 C CD1 . LEU A 1 168 ? -19.43606 6.73682   16.75004 1.000 37.39498 ? 195 LEU A CD1 1 
ATOM   1318 C CD2 . LEU A 1 168 ? -19.03365 9.19144   17.02012 1.000 37.09582 ? 195 LEU A CD2 1 
ATOM   1319 N N   . GLY A 1 169 ? -20.27215 7.94053   22.16708 1.000 31.02220 ? 196 GLY A N   1 
ATOM   1320 C CA  . GLY A 1 169 ? -21.11505 7.85989   23.34523 1.000 34.70908 ? 196 GLY A CA  1 
ATOM   1321 C C   . GLY A 1 169 ? -20.70981 8.83413   24.42770 1.000 31.90376 ? 196 GLY A C   1 
ATOM   1322 O O   . GLY A 1 169 ? -20.07863 9.86239   24.17328 1.000 36.20406 ? 196 GLY A O   1 
ATOM   1323 N N   . HIS A 1 170 ? -21.13655 8.53539   25.64939 1.000 31.33196 ? 197 HIS A N   1 
ATOM   1324 C CA  . HIS A 1 170 ? -21.00324 9.48760   26.74906 1.000 31.58259 ? 197 HIS A CA  1 
ATOM   1325 C C   . HIS A 1 170 ? -20.26384 8.88133   27.93875 1.000 30.74427 ? 197 HIS A C   1 
ATOM   1326 O O   . HIS A 1 170 ? -20.54160 9.21713   29.10659 1.000 32.69097 ? 197 HIS A O   1 
ATOM   1327 C CB  . HIS A 1 170 ? -22.38451 10.02651  27.15409 1.000 34.02501 ? 197 HIS A CB  1 
ATOM   1328 C CG  . HIS A 1 170 ? -23.02293 10.87200  26.09480 1.000 35.44499 ? 197 HIS A CG  1 
ATOM   1329 N ND1 . HIS A 1 170 ? -22.88592 12.24559  26.05372 1.000 48.05872 ? 197 HIS A ND1 1 
ATOM   1330 C CD2 . HIS A 1 170 ? -23.75984 10.53536  25.00843 1.000 43.76054 ? 197 HIS A CD2 1 
ATOM   1331 C CE1 . HIS A 1 170 ? -23.52623 12.71765  24.99930 1.000 51.60423 ? 197 HIS A CE1 1 
ATOM   1332 N NE2 . HIS A 1 170 ? -24.05706 11.69998  24.34309 1.000 49.56273 ? 197 HIS A NE2 1 
ATOM   1333 N N   . ALA A 1 171 ? -19.27386 8.01285   27.68249 1.000 29.20279 ? 198 ALA A N   1 
ATOM   1334 C CA  . ALA A 1 171 ? -18.42379 7.52111   28.76207 1.000 31.74843 ? 198 ALA A CA  1 
ATOM   1335 C C   . ALA A 1 171 ? -17.55553 8.62846   29.33613 1.000 29.72813 ? 198 ALA A C   1 
ATOM   1336 O O   . ALA A 1 171 ? -17.14174 8.54914   30.50131 1.000 31.47118 ? 198 ALA A O   1 
ATOM   1337 C CB  . ALA A 1 171 ? -17.53257 6.37209   28.27678 1.000 29.96499 ? 198 ALA A CB  1 
ATOM   1338 N N   . LEU A 1 172 ? -17.27182 9.65256   28.54717 1.000 26.38370 ? 199 LEU A N   1 
ATOM   1339 C CA  . LEU A 1 172 ? -16.52680 10.82419  28.98080 1.000 30.35179 ? 199 LEU A CA  1 
ATOM   1340 C C   . LEU A 1 172 ? -17.42392 12.06341  28.93806 1.000 32.23388 ? 199 LEU A C   1 
ATOM   1341 O O   . LEU A 1 172 ? -18.39617 12.12895  28.18275 1.000 33.37648 ? 199 LEU A O   1 
ATOM   1342 C CB  . LEU A 1 172 ? -15.31524 11.04527  28.07012 1.000 26.11331 ? 199 LEU A CB  1 
ATOM   1343 C CG  . LEU A 1 172 ? -14.31779 9.89178   27.97894 1.000 24.25518 ? 199 LEU A CG  1 
ATOM   1344 C CD1 . LEU A 1 172 ? -13.41190 10.25858  26.84990 1.000 24.29474 ? 199 LEU A CD1 1 
ATOM   1345 C CD2 . LEU A 1 172 ? -13.54629 9.83592   29.25719 1.000 27.68502 ? 199 LEU A CD2 1 
ATOM   1346 N N   . GLY A 1 173 ? -17.05037 13.06933  29.71823 1.000 29.44697 ? 200 GLY A N   1 
ATOM   1347 C CA  . GLY A 1 173 ? -17.68471 14.37632  29.62282 1.000 31.30873 ? 200 GLY A CA  1 
ATOM   1348 C C   . GLY A 1 173 ? -17.52043 14.98879  28.23129 1.000 35.07930 ? 200 GLY A C   1 
ATOM   1349 O O   . GLY A 1 173 ? -16.67875 14.59477  27.43326 1.000 30.70381 ? 200 GLY A O   1 
ATOM   1350 N N   A GLU A 1 174 ? -18.32753 16.01938  27.96300 0.668 33.63325 ? 201 GLU A N   1 
ATOM   1351 N N   B GLU A 1 174 ? -18.32443 16.02543  27.97890 0.332 33.63666 ? 201 GLU A N   1 
ATOM   1352 C CA  A GLU A 1 174 ? -18.38559 16.56022  26.60796 0.668 34.38725 ? 201 GLU A CA  1 
ATOM   1353 C CA  B GLU A 1 174 ? -18.41331 16.58877  26.63496 0.332 34.44186 ? 201 GLU A CA  1 
ATOM   1354 C C   A GLU A 1 174 ? -17.06001 17.16759  26.16771 0.668 34.02777 ? 201 GLU A C   1 
ATOM   1355 C C   B GLU A 1 174 ? -17.08811 17.18651  26.17103 0.332 34.07243 ? 201 GLU A C   1 
ATOM   1356 O O   A GLU A 1 174 ? -16.65505 16.99900  25.01260 0.668 34.76729 ? 201 GLU A O   1 
ATOM   1357 O O   B GLU A 1 174 ? -16.68962 16.99577  25.01631 0.332 34.77670 ? 201 GLU A O   1 
ATOM   1358 C CB  A GLU A 1 174 ? -19.49875 17.60058  26.50045 0.668 36.61928 ? 201 GLU A CB  1 
ATOM   1359 C CB  B GLU A 1 174 ? -19.52450 17.63922  26.58900 0.332 36.67968 ? 201 GLU A CB  1 
ATOM   1360 C CG  A GLU A 1 174 ? -20.85900 17.00780  26.74036 0.668 42.48122 ? 201 GLU A CG  1 
ATOM   1361 C CG  B GLU A 1 174 ? -20.87335 17.11729  27.07395 0.332 40.42467 ? 201 GLU A CG  1 
ATOM   1362 C CD  A GLU A 1 174 ? -21.33202 17.18014  28.16377 0.668 37.82010 ? 201 GLU A CD  1 
ATOM   1363 C CD  B GLU A 1 174 ? -21.54743 16.19857  26.06275 0.332 42.18073 ? 201 GLU A CD  1 
ATOM   1364 O OE1 A GLU A 1 174 ? -20.50676 17.13871  29.09545 0.668 46.46922 ? 201 GLU A OE1 1 
ATOM   1365 O OE1 B GLU A 1 174 ? -20.96633 15.96867  24.98449 0.332 37.91013 ? 201 GLU A OE1 1 
ATOM   1366 O OE2 A GLU A 1 174 ? -22.55064 17.38556  28.34758 0.668 56.91130 ? 201 GLU A OE2 1 
ATOM   1367 O OE2 B GLU A 1 174 ? -22.66725 15.71817  26.34293 0.332 48.58639 ? 201 GLU A OE2 1 
ATOM   1368 N N   . THR A 1 175 ? -16.41362 17.95210  27.03375 1.000 34.35093 ? 202 THR A N   1 
ATOM   1369 C CA  A THR A 1 175 ? -15.12296 18.52325  26.65911 0.625 34.13782 ? 202 THR A CA  1 
ATOM   1370 C CA  B THR A 1 175 ? -15.12346 18.52107  26.65094 0.375 34.13659 ? 202 THR A CA  1 
ATOM   1371 C C   . THR A 1 175 ? -14.08708 17.42588  26.44065 1.000 32.34963 ? 202 THR A C   1 
ATOM   1372 O O   . THR A 1 175 ? -13.28166 17.48985  25.50202 1.000 31.84071 ? 202 THR A O   1 
ATOM   1373 C CB  A THR A 1 175 ? -14.64607 19.49931  27.73246 0.625 38.98801 ? 202 THR A CB  1 
ATOM   1374 C CB  B THR A 1 175 ? -14.63404 19.50720  27.71259 0.375 38.89142 ? 202 THR A CB  1 
ATOM   1375 O OG1 A THR A 1 175 ? -14.57201 18.82639  28.98810 0.625 39.69496 ? 202 THR A OG1 1 
ATOM   1376 O OG1 B THR A 1 175 ? -15.59416 20.56244  27.86762 0.375 37.52171 ? 202 THR A OG1 1 
ATOM   1377 C CG2 A THR A 1 175 ? -15.62767 20.65567  27.86237 0.625 37.54133 ? 202 THR A CG2 1 
ATOM   1378 C CG2 B THR A 1 175 ? -13.28645 20.10661  27.30321 0.375 34.84632 ? 202 THR A CG2 1 
ATOM   1379 N N   . GLN A 1 176 ? -14.10425 16.41846  27.30679 1.000 30.85054 ? 203 GLN A N   1 
ATOM   1380 C CA  . GLN A 1 176 ? -13.13661 15.34063  27.23092 1.000 29.00879 ? 203 GLN A CA  1 
ATOM   1381 C C   . GLN A 1 176 ? -13.31436 14.53240  25.95550 1.000 33.70832 ? 203 GLN A C   1 
ATOM   1382 O O   . GLN A 1 176 ? -12.32614 14.16577  25.30246 1.000 27.45012 ? 203 GLN A O   1 
ATOM   1383 C CB  . GLN A 1 176 ? -13.30696 14.45135  28.45335 1.000 28.07274 ? 203 GLN A CB  1 
ATOM   1384 C CG  . GLN A 1 176 ? -12.78087 15.06253  29.73472 1.000 28.39114 ? 203 GLN A CG  1 
ATOM   1385 C CD  . GLN A 1 176 ? -13.68808 16.14807  30.30091 1.000 30.17405 ? 203 GLN A CD  1 
ATOM   1386 O OE1 . GLN A 1 176 ? -14.91246 16.16786  30.06428 1.000 31.03812 ? 203 GLN A OE1 1 
ATOM   1387 N NE2 . GLN A 1 176 ? -13.09307 17.05818  31.05514 1.000 36.08697 ? 203 GLN A NE2 1 
ATOM   1388 N N   . ARG A 1 177 ? -14.56315 14.17850  25.63666 1.000 28.83191 ? 204 ARG A N   1 
ATOM   1389 C CA  . ARG A 1 177 ? -14.83800 13.43384  24.41101 1.000 28.39779 ? 204 ARG A CA  1 
ATOM   1390 C C   . ARG A 1 177 ? -14.36758 14.20905  23.19499 1.000 29.16503 ? 204 ARG A C   1 
ATOM   1391 O O   . ARG A 1 177 ? -13.75054 13.64318  22.28113 1.000 28.35407 ? 204 ARG A O   1 
ATOM   1392 C CB  . ARG A 1 177 ? -16.33458 13.14724  24.32994 1.000 29.90681 ? 204 ARG A CB  1 
ATOM   1393 C CG  . ARG A 1 177 ? -16.81804 12.42556  23.09766 1.000 39.51850 ? 204 ARG A CG  1 
ATOM   1394 C CD  . ARG A 1 177 ? -18.31272 12.30625  23.18622 1.000 43.98519 ? 204 ARG A CD  1 
ATOM   1395 N NE  . ARG A 1 177 ? -18.95458 13.57743  22.89471 1.000 45.34465 ? 204 ARG A NE  1 
ATOM   1396 C CZ  . ARG A 1 177 ? -20.25809 13.72388  22.69912 1.000 55.89694 ? 204 ARG A CZ  1 
ATOM   1397 N NH1 . ARG A 1 177 ? -21.08807 12.69433  22.79094 1.000 52.68365 ? 204 ARG A NH1 1 
ATOM   1398 N NH2 . ARG A 1 177 ? -20.74083 14.93313  22.41018 1.000 49.04247 ? 204 ARG A NH2 1 
ATOM   1399 N N   . ALA A 1 178 ? -14.66218 15.50927  23.14661 1.000 30.86071 ? 205 ALA A N   1 
ATOM   1400 C CA  . ALA A 1 178 ? -14.26259 16.29724  21.99064 1.000 31.84590 ? 205 ALA A CA  1 
ATOM   1401 C C   . ALA A 1 178 ? -12.75318 16.32162  21.85209 1.000 31.00154 ? 205 ALA A C   1 
ATOM   1402 O O   . ALA A 1 178 ? -12.22264 16.29142  20.72836 1.000 31.04915 ? 205 ALA A O   1 
ATOM   1403 C CB  . ALA A 1 178 ? -14.82365 17.72953  22.10056 1.000 33.95211 ? 205 ALA A CB  1 
ATOM   1404 N N   . GLN A 1 179 ? -12.04817 16.37470  22.98921 1.000 30.34361 ? 206 GLN A N   1 
ATOM   1405 C CA  . GLN A 1 179 ? -10.59511 16.35606  22.97995 1.000 29.59451 ? 206 GLN A CA  1 
ATOM   1406 C C   . GLN A 1 179 ? -10.07288 15.03019  22.43050 1.000 27.92609 ? 206 GLN A C   1 
ATOM   1407 O O   . GLN A 1 179 ? -9.15641  15.00022  21.59080 1.000 27.76831 ? 206 GLN A O   1 
ATOM   1408 C CB  . GLN A 1 179 ? -10.06127 16.58103  24.39795 1.000 29.26373 ? 206 GLN A CB  1 
ATOM   1409 C CG  . GLN A 1 179 ? -8.55758  16.64558  24.47331 1.000 36.25524 ? 206 GLN A CG  1 
ATOM   1410 C CD  . GLN A 1 179 ? -7.98729  17.79132  23.66212 1.000 39.89631 ? 206 GLN A CD  1 
ATOM   1411 O OE1 . GLN A 1 179 ? -7.82004  18.89678  24.15897 1.000 46.86056 ? 206 GLN A OE1 1 
ATOM   1412 N NE2 . GLN A 1 179 ? -7.66933  17.52566  22.41276 1.000 35.05121 ? 206 GLN A NE2 1 
ATOM   1413 N N   . LEU A 1 180 ? -10.65801 13.92286  22.88401 1.000 26.79468 ? 207 LEU A N   1 
ATOM   1414 C CA  . LEU A 1 180 ? -10.23795 12.62555  22.38737 1.000 25.28798 ? 207 LEU A CA  1 
ATOM   1415 C C   . LEU A 1 180 ? -10.45249 12.52688  20.87833 1.000 25.71703 ? 207 LEU A C   1 
ATOM   1416 O O   . LEU A 1 180 ? -9.56367  12.06883  20.15086 1.000 27.22603 ? 207 LEU A O   1 
ATOM   1417 C CB  . LEU A 1 180 ? -10.97749 11.52141  23.14775 1.000 24.46959 ? 207 LEU A CB  1 
ATOM   1418 C CG  . LEU A 1 180 ? -10.58078 10.10250  22.70727 1.000 23.12275 ? 207 LEU A CG  1 
ATOM   1419 C CD1 . LEU A 1 180 ? -9.11001  9.84470   23.04708 1.000 27.16785 ? 207 LEU A CD1 1 
ATOM   1420 C CD2 . LEU A 1 180 ? -11.48339 9.15244   23.49408 1.000 26.34684 ? 207 LEU A CD2 1 
ATOM   1421 N N   . VAL A 1 181 ? -11.62501 12.95867  20.39138 1.000 26.93068 ? 208 VAL A N   1 
ATOM   1422 C CA  . VAL A 1 181 ? -11.90044 12.89550  18.94896 1.000 27.52846 ? 208 VAL A CA  1 
ATOM   1423 C C   . VAL A 1 181 ? -10.87479 13.71399  18.18119 1.000 33.13494 ? 208 VAL A C   1 
ATOM   1424 O O   . VAL A 1 181 ? -10.32061 13.26478  17.16649 1.000 27.97038 ? 208 VAL A O   1 
ATOM   1425 C CB  . VAL A 1 181 ? -13.33074 13.37472  18.66560 1.000 28.98540 ? 208 VAL A CB  1 
ATOM   1426 C CG1 . VAL A 1 181 ? -13.52821 13.63025  17.17280 1.000 36.07249 ? 208 VAL A CG1 1 
ATOM   1427 C CG2 . VAL A 1 181 ? -14.32383 12.36040  19.20209 1.000 33.77460 ? 208 VAL A CG2 1 
ATOM   1428 N N   . THR A 1 182 ? -10.60024 14.92652  18.66450 1.000 29.39746 ? 209 THR A N   1 
ATOM   1429 C CA  . THR A 1 182 ? -9.63030  15.79665  18.01185 1.000 30.36408 ? 209 THR A CA  1 
ATOM   1430 C C   . THR A 1 182 ? -8.25066  15.14843  17.95746 1.000 29.08575 ? 209 THR A C   1 
ATOM   1431 O O   . THR A 1 182 ? -7.58041  15.18208  16.91551 1.000 30.04305 ? 209 THR A O   1 
ATOM   1432 C CB  . THR A 1 182 ? -9.57800  17.12812  18.74515 1.000 38.54711 ? 209 THR A CB  1 
ATOM   1433 O OG1 . THR A 1 182 ? -10.82532 17.79529  18.54219 1.000 34.38052 ? 209 THR A OG1 1 
ATOM   1434 C CG2 . THR A 1 182 ? -8.42526  17.98113  18.23394 1.000 39.92027 ? 209 THR A CG2 1 
ATOM   1435 N N   . TRP A 1 183 ? -7.82712  14.52530  19.05328 1.000 27.69151 ? 210 TRP A N   1 
ATOM   1436 C CA  . TRP A 1 183 ? -6.54787  13.81336  19.04981 1.000 26.48198 ? 210 TRP A CA  1 
ATOM   1437 C C   . TRP A 1 183 ? -6.53372  12.68522  18.02244 1.000 25.60894 ? 210 TRP A C   1 
ATOM   1438 O O   . TRP A 1 183 ? -5.57717  12.55787  17.24432 1.000 27.25331 ? 210 TRP A O   1 
ATOM   1439 C CB  . TRP A 1 183 ? -6.24840  13.23825  20.43809 1.000 25.18375 ? 210 TRP A CB  1 
ATOM   1440 C CG  . TRP A 1 183 ? -5.74218  14.29812  21.40731 1.000 29.95291 ? 210 TRP A CG  1 
ATOM   1441 C CD1 . TRP A 1 183 ? -5.11231  15.48423  21.09660 1.000 31.90463 ? 210 TRP A CD1 1 
ATOM   1442 C CD2 . TRP A 1 183 ? -5.83605  14.26187  22.84329 1.000 26.48443 ? 210 TRP A CD2 1 
ATOM   1443 N NE1 . TRP A 1 183 ? -4.80259  16.16906  22.26368 1.000 32.59090 ? 210 TRP A NE1 1 
ATOM   1444 C CE2 . TRP A 1 183 ? -5.24505  15.44701  23.33736 1.000 30.58416 ? 210 TRP A CE2 1 
ATOM   1445 C CE3 . TRP A 1 183 ? -6.38171  13.34547  23.76150 1.000 29.01229 ? 210 TRP A CE3 1 
ATOM   1446 C CZ2 . TRP A 1 183 ? -5.16254  15.73215  24.71318 1.000 29.99912 ? 210 TRP A CZ2 1 
ATOM   1447 C CZ3 . TRP A 1 183 ? -6.30157  13.63327  25.13333 1.000 29.12181 ? 210 TRP A CZ3 1 
ATOM   1448 C CH2 . TRP A 1 183 ? -5.70066  14.81773  25.58770 1.000 31.51324 ? 210 TRP A CH2 1 
ATOM   1449 N N   . LEU A 1 184 ? -7.57850  11.84520  18.00899 1.000 24.94570 ? 211 LEU A N   1 
ATOM   1450 C CA  . LEU A 1 184 ? -7.60658  10.70771  17.07325 1.000 25.68014 ? 211 LEU A CA  1 
ATOM   1451 C C   . LEU A 1 184 ? -7.58513  11.17985  15.62896 1.000 27.61296 ? 211 LEU A C   1 
ATOM   1452 O O   . LEU A 1 184 ? -6.91724  10.56848  14.77220 1.000 26.37270 ? 211 LEU A O   1 
ATOM   1453 C CB  . LEU A 1 184 ? -8.84690  9.85194   17.30368 1.000 23.51900 ? 211 LEU A CB  1 
ATOM   1454 C CG  . LEU A 1 184 ? -8.86523  9.10221   18.66067 1.000 28.25226 ? 211 LEU A CG  1 
ATOM   1455 C CD1 . LEU A 1 184 ? -10.18548 8.38537   18.86298 1.000 27.78579 ? 211 LEU A CD1 1 
ATOM   1456 C CD2 . LEU A 1 184 ? -7.72891  8.12922   18.73618 1.000 28.04359 ? 211 LEU A CD2 1 
ATOM   1457 N N   . LYS A 1 185 ? -8.34843  12.23741  15.33229 1.000 26.95676 ? 212 LYS A N   1 
ATOM   1458 C CA  . LYS A 1 185 ? -8.37623  12.74405  13.97296 1.000 28.34727 ? 212 LYS A CA  1 
ATOM   1459 C C   . LYS A 1 185 ? -7.00951  13.24468  13.52934 1.000 30.90227 ? 212 LYS A C   1 
ATOM   1460 O O   . LYS A 1 185 ? -6.71553  13.24751  12.32561 1.000 32.24113 ? 212 LYS A O   1 
ATOM   1461 C CB  . LYS A 1 185 ? -9.42809  13.84466  13.83958 1.000 32.39721 ? 212 LYS A CB  1 
ATOM   1462 C CG  . LYS A 1 185 ? -10.88105 13.34035  13.77042 1.000 30.15695 ? 212 LYS A CG  1 
ATOM   1463 C CD  . LYS A 1 185 ? -11.84866 14.53492  13.56738 1.000 39.77501 ? 212 LYS A CD  1 
ATOM   1464 C CE  . LYS A 1 185 ? -13.32817 14.17707  13.80270 1.000 44.91894 ? 212 LYS A CE  1 
ATOM   1465 N NZ  . LYS A 1 185 ? -14.31643 15.32985  13.56991 1.000 47.54538 ? 212 LYS A NZ  1 
ATOM   1466 N N   . GLY A 1 186 ? -6.16837  13.66126  14.45846 1.000 28.59110 ? 213 GLY A N   1 
ATOM   1467 C CA  . GLY A 1 186 ? -4.85706  14.16148  14.13015 1.000 32.30211 ? 213 GLY A CA  1 
ATOM   1468 C C   . GLY A 1 186 ? -3.76234  13.12844  14.15914 1.000 30.46481 ? 213 GLY A C   1 
ATOM   1469 O O   . GLY A 1 186 ? -2.58292  13.49606  14.19170 1.000 29.42082 ? 213 GLY A O   1 
ATOM   1470 N N   . ASN A 1 187 ? -4.10841  11.83736  14.19372 1.000 26.22412 ? 214 ASN A N   1 
ATOM   1471 C CA  . ASN A 1 187 ? -3.08036  10.81527  14.21301 1.000 26.99725 ? 214 ASN A CA  1 
ATOM   1472 C C   . ASN A 1 187 ? -2.19454  10.92786  12.97929 1.000 26.23805 ? 214 ASN A C   1 
ATOM   1473 O O   . ASN A 1 187 ? -2.67916  11.19455  11.87587 1.000 27.15742 ? 214 ASN A O   1 
ATOM   1474 C CB  . ASN A 1 187 ? -3.72782  9.42411   14.25171 1.000 24.16555 ? 214 ASN A CB  1 
ATOM   1475 C CG  . ASN A 1 187 ? -2.71533  8.34232   14.26780 1.000 26.04892 ? 214 ASN A CG  1 
ATOM   1476 O OD1 . ASN A 1 187 ? -1.69042  8.48733   14.91543 1.000 25.72988 ? 214 ASN A OD1 1 
ATOM   1477 N ND2 . ASN A 1 187 ? -2.98064  7.23733   13.55982 1.000 23.29197 ? 214 ASN A ND2 1 
ATOM   1478 N N   . THR A 1 188 ? -0.89416  10.69494  13.15954 1.000 27.05899 ? 215 THR A N   1 
ATOM   1479 C CA  . THR A 1 188 ? 0.05790   10.77354  12.05208 1.000 27.83276 ? 215 THR A CA  1 
ATOM   1480 C C   . THR A 1 188 ? 0.50830   9.41219   11.53612 1.000 25.53345 ? 215 THR A C   1 
ATOM   1481 O O   . THR A 1 188 ? 1.18273   9.36098   10.51233 1.000 26.67374 ? 215 THR A O   1 
ATOM   1482 C CB  . THR A 1 188 ? 1.29719   11.59957  12.46297 1.000 27.25925 ? 215 THR A CB  1 
ATOM   1483 O OG1 . THR A 1 188 ? 2.14256   10.82877  13.33650 1.000 26.20536 ? 215 THR A OG1 1 
ATOM   1484 C CG2 . THR A 1 188 ? 0.87891   12.90239  13.14847 1.000 34.56145 ? 215 THR A CG2 1 
ATOM   1485 N N   . THR A 1 189 ? 0.14264   8.31057   12.18746 1.000 24.45060 ? 216 THR A N   1 
ATOM   1486 C CA  . THR A 1 189 ? 0.73627   7.01485   11.87769 1.000 26.34217 ? 216 THR A CA  1 
ATOM   1487 C C   . THR A 1 189 ? -0.17058  6.11763   11.05206 1.000 23.18024 ? 216 THR A C   1 
ATOM   1488 O O   . THR A 1 189 ? 0.18517   4.96583   10.81994 1.000 25.99790 ? 216 THR A O   1 
ATOM   1489 C CB  . THR A 1 189 ? 1.10674   6.24078   13.15437 1.000 27.87705 ? 216 THR A CB  1 
ATOM   1490 O OG1 . THR A 1 189 ? -0.08581  5.88097   13.86018 1.000 24.25658 ? 216 THR A OG1 1 
ATOM   1491 C CG2 . THR A 1 189 ? 2.00497   7.04240   14.10093 1.000 26.63406 ? 216 THR A CG2 1 
ATOM   1492 N N   . GLY A 1 190 ? -1.33778  6.58616   10.63803 1.000 25.48651 ? 217 GLY A N   1 
ATOM   1493 C CA  . GLY A 1 190 ? -2.33665  5.67055   10.12348 1.000 27.49161 ? 217 GLY A CA  1 
ATOM   1494 C C   . GLY A 1 190 ? -2.52838  5.66411   8.62334  1.000 23.62310 ? 217 GLY A C   1 
ATOM   1495 O O   . GLY A 1 190 ? -3.42980  4.96732   8.14295  1.000 28.79850 ? 217 GLY A O   1 
ATOM   1496 N N   . ALA A 1 191 ? -1.68165  6.35740   7.85671  1.000 25.62691 ? 218 ALA A N   1 
ATOM   1497 C CA  . ALA A 1 191 ? -2.00418  6.56619   6.44428  1.000 25.88551 ? 218 ALA A CA  1 
ATOM   1498 C C   . ALA A 1 191 ? -2.08303  5.25743   5.65303  1.000 27.65658 ? 218 ALA A C   1 
ATOM   1499 O O   . ALA A 1 191 ? -2.82616  5.17356   4.66767  1.000 34.64048 ? 218 ALA A O   1 
ATOM   1500 C CB  . ALA A 1 191 ? -0.98893  7.51970   5.80113  1.000 27.90145 ? 218 ALA A CB  1 
ATOM   1501 N N   . ALA A 1 192 ? -1.34591  4.23525   6.04912  1.000 23.78776 ? 219 ALA A N   1 
ATOM   1502 C CA  . ALA A 1 192 ? -1.27728  3.01741   5.25488  1.000 25.29544 ? 219 ALA A CA  1 
ATOM   1503 C C   . ALA A 1 192 ? -2.15818  1.89910   5.81693  1.000 27.23402 ? 219 ALA A C   1 
ATOM   1504 O O   . ALA A 1 192 ? -2.17018  0.78811   5.25498  1.000 25.05707 ? 219 ALA A O   1 
ATOM   1505 C CB  . ALA A 1 192 ? 0.16923   2.54186   5.14788  1.000 25.83305 ? 219 ALA A CB  1 
ATOM   1506 N N   . SER A 1 193 ? -2.93862  2.17867   6.85011  1.000 24.73116 ? 220 SER A N   1 
ATOM   1507 C CA  . SER A 1 193 ? -3.73652  1.15598   7.52488  1.000 21.82484 ? 220 SER A CA  1 
ATOM   1508 C C   . SER A 1 193 ? -5.20363  1.34886   7.13199  1.000 20.93240 ? 220 SER A C   1 
ATOM   1509 O O   . SER A 1 193 ? -5.48775  1.40116   5.92214  1.000 22.98699 ? 220 SER A O   1 
ATOM   1510 C CB  . SER A 1 193 ? -3.46648  1.18815   9.02780  1.000 20.45552 ? 220 SER A CB  1 
ATOM   1511 O OG  . SER A 1 193 ? -2.11971  0.85434   9.29244  1.000 23.72428 ? 220 SER A OG  1 
ATOM   1512 N N   . ILE A 1 194 ? -6.13800  1.44348   8.08977  1.000 20.32130 ? 221 ILE A N   1 
ATOM   1513 C CA  . ILE A 1 194 ? -7.55726  1.52897   7.72780  1.000 21.59139 ? 221 ILE A CA  1 
ATOM   1514 C C   . ILE A 1 194 ? -7.81360  2.63726   6.71248  1.000 25.11224 ? 221 ILE A C   1 
ATOM   1515 O O   . ILE A 1 194 ? -8.58983  2.44798   5.76627  1.000 26.25750 ? 221 ILE A O   1 
ATOM   1516 C CB  . ILE A 1 194 ? -8.42444  1.69767   8.98534  1.000 20.82130 ? 221 ILE A CB  1 
ATOM   1517 C CG1 . ILE A 1 194 ? -8.53111  0.35082   9.70304  1.000 23.09591 ? 221 ILE A CG1 1 
ATOM   1518 C CG2 . ILE A 1 194 ? -9.80908  2.26074   8.58028  1.000 23.38416 ? 221 ILE A CG2 1 
ATOM   1519 C CD1 . ILE A 1 194 ? -9.13693  0.45524   11.11470 1.000 21.04285 ? 221 ILE A CD1 1 
ATOM   1520 N N   . ARG A 1 195 ? -7.16876  3.80574   6.89293  1.000 24.47538 ? 222 ARG A N   1 
ATOM   1521 C CA  . ARG A 1 195 ? -7.42119  4.96605   6.02999  1.000 26.52141 ? 222 ARG A CA  1 
ATOM   1522 C C   . ARG A 1 195 ? -7.17824  4.62987   4.56676  1.000 29.71030 ? 222 ARG A C   1 
ATOM   1523 O O   . ARG A 1 195 ? -7.86482  5.14915   3.67413  1.000 29.08255 ? 222 ARG A O   1 
ATOM   1524 C CB  . ARG A 1 195 ? -6.53276  6.14307   6.45876  1.000 32.13811 ? 222 ARG A CB  1 
ATOM   1525 C CG  . ARG A 1 195 ? -6.90780  6.76950   7.82154  1.000 40.49663 ? 222 ARG A CG  1 
ATOM   1526 C CD  . ARG A 1 195 ? -5.86251  7.81162   8.28103  1.000 34.53849 ? 222 ARG A CD  1 
ATOM   1527 N NE  . ARG A 1 195 ? -5.97596  8.22326   9.68561  1.000 32.84893 ? 222 ARG A NE  1 
ATOM   1528 C CZ  . ARG A 1 195 ? -6.41422  9.41082   10.08715 1.000 45.52713 ? 222 ARG A CZ  1 
ATOM   1529 N NH1 . ARG A 1 195 ? -6.82927  10.32388  9.21135  1.000 46.31081 ? 222 ARG A NH1 1 
ATOM   1530 N NH2 . ARG A 1 195 ? -6.41905  9.69799   11.39920 1.000 36.16040 ? 222 ARG A NH2 1 
ATOM   1531 N N   . ALA A 1 196 ? -6.22514  3.74838   4.30180  1.000 25.20165 ? 223 ALA A N   1 
ATOM   1532 C CA  . ALA A 1 196 ? -5.86208  3.46729   2.91442  1.000 27.38729 ? 223 ALA A CA  1 
ATOM   1533 C C   . ALA A 1 196 ? -6.93323  2.66894   2.17160  1.000 29.96553 ? 223 ALA A C   1 
ATOM   1534 O O   . ALA A 1 196 ? -6.93166  2.65700   0.93291  1.000 33.85791 ? 223 ALA A O   1 
ATOM   1535 C CB  . ALA A 1 196 ? -4.51513  2.74489   2.90054  1.000 28.41069 ? 223 ALA A CB  1 
ATOM   1536 N N   . GLY A 1 197 ? -7.83558  1.99327   2.88105  1.000 29.68787 ? 224 GLY A N   1 
ATOM   1537 C CA  . GLY A 1 197 ? -8.88485  1.21280   2.25951  1.000 30.79206 ? 224 GLY A CA  1 
ATOM   1538 C C   . GLY A 1 197 ? -10.20308 1.93365   2.13625  1.000 31.59772 ? 224 GLY A C   1 
ATOM   1539 O O   . GLY A 1 197 ? -11.16225 1.35454   1.61227  1.000 35.99987 ? 224 GLY A O   1 
ATOM   1540 N N   . LEU A 1 198 ? -10.26675 3.20905   2.53272  1.000 34.69228 ? 225 LEU A N   1 
ATOM   1541 C CA  . LEU A 1 198 ? -11.51906 3.95809   2.60521  1.000 32.98273 ? 225 LEU A CA  1 
ATOM   1542 C C   . LEU A 1 198 ? -11.56160 5.10388   1.60009  1.000 35.54300 ? 225 LEU A C   1 
ATOM   1543 O O   . LEU A 1 198 ? -10.52638 5.69909   1.27575  1.000 38.49666 ? 225 LEU A O   1 
ATOM   1544 C CB  . LEU A 1 198 ? -11.73577 4.54443   4.00507  1.000 33.07440 ? 225 LEU A CB  1 
ATOM   1545 C CG  . LEU A 1 198 ? -11.80150 3.54609   5.16618  1.000 33.73064 ? 225 LEU A CG  1 
ATOM   1546 C CD1 . LEU A 1 198 ? -12.07543 4.33106   6.44890  1.000 32.84104 ? 225 LEU A CD1 1 
ATOM   1547 C CD2 . LEU A 1 198 ? -12.87058 2.50216   4.90834  1.000 32.50591 ? 225 LEU A CD2 1 
ATOM   1548 N N   . PRO A 1 199 ? -12.75652 5.46218   1.13305  1.000 40.04292 ? 226 PRO A N   1 
ATOM   1549 C CA  . PRO A 1 199 ? -12.89807 6.65422   0.28272  1.000 45.48683 ? 226 PRO A CA  1 
ATOM   1550 C C   . PRO A 1 199 ? -12.21682 7.87000   0.89799  1.000 54.91261 ? 226 PRO A C   1 
ATOM   1551 O O   . PRO A 1 199 ? -12.36925 8.15616   2.09272  1.000 45.71597 ? 226 PRO A O   1 
ATOM   1552 C CB  . PRO A 1 199 ? -14.41701 6.84324   0.18975  1.000 49.64042 ? 226 PRO A CB  1 
ATOM   1553 C CG  . PRO A 1 199 ? -14.99988 5.50231   0.44593  1.000 44.88639 ? 226 PRO A CG  1 
ATOM   1554 C CD  . PRO A 1 199 ? -14.05293 4.82563   1.44229  1.000 36.51100 ? 226 PRO A CD  1 
ATOM   1555 N N   . THR A 1 200 ? -11.46710 8.60310   0.06510  1.000 54.12158 ? 227 THR A N   1 
ATOM   1556 C CA  . THR A 1 200 ? -10.61620 9.68178   0.56102  1.000 53.44114 ? 227 THR A CA  1 
ATOM   1557 C C   . THR A 1 200 ? -11.40566 10.85506  1.11758  1.000 54.79754 ? 227 THR A C   1 
ATOM   1558 O O   . THR A 1 200 ? -10.81391 11.72070  1.77570  1.000 64.29758 ? 227 THR A O   1 
ATOM   1559 C CB  . THR A 1 200 ? -9.67807  10.18707  -0.53724 1.000 61.12597 ? 227 THR A CB  1 
ATOM   1560 O OG1 . THR A 1 200 ? -10.43378 10.50171  -1.71633 1.000 63.37915 ? 227 THR A OG1 1 
ATOM   1561 C CG2 . THR A 1 200 ? -8.62034  9.13332   -0.86288 1.000 62.76526 ? 227 THR A CG2 1 
ATOM   1562 N N   . SER A 1 201 ? -12.71376 10.89951  0.88994  1.000 49.58860 ? 228 SER A N   1 
ATOM   1563 C CA  . SER A 1 201 ? -13.53537 11.96855  1.43314  1.000 60.51658 ? 228 SER A CA  1 
ATOM   1564 C C   . SER A 1 201 ? -14.01980 11.68410  2.84633  1.000 53.08223 ? 228 SER A C   1 
ATOM   1565 O O   . SER A 1 201 ? -14.54579 12.59503  3.48798  1.000 53.21446 ? 228 SER A O   1 
ATOM   1566 C CB  . SER A 1 201 ? -14.74852 12.23446  0.52975  1.000 53.96128 ? 228 SER A CB  1 
ATOM   1567 O OG  . SER A 1 201 ? -15.72817 11.21360  0.64846  1.000 59.35428 ? 228 SER A OG  1 
ATOM   1568 N N   . TRP A 1 202 ? -13.86647 10.45383  3.34139  1.000 52.06342 ? 229 TRP A N   1 
ATOM   1569 C CA  . TRP A 1 202 ? -14.29034 10.11757  4.69129  1.000 51.19221 ? 229 TRP A CA  1 
ATOM   1570 C C   . TRP A 1 202 ? -13.27632 10.62030  5.70454  1.000 49.55926 ? 229 TRP A C   1 
ATOM   1571 O O   . TRP A 1 202 ? -12.06549 10.56520  5.47060  1.000 46.10697 ? 229 TRP A O   1 
ATOM   1572 C CB  . TRP A 1 202 ? -14.45711 8.61300   4.84271  1.000 49.76973 ? 229 TRP A CB  1 
ATOM   1573 C CG  . TRP A 1 202 ? -15.57879 8.04647   4.04568  1.000 44.80385 ? 229 TRP A CG  1 
ATOM   1574 C CD1 . TRP A 1 202 ? -16.32783 8.69147   3.09417  1.000 55.99142 ? 229 TRP A CD1 1 
ATOM   1575 C CD2 . TRP A 1 202 ? -16.09213 6.71022   4.12497  1.000 46.90227 ? 229 TRP A CD2 1 
ATOM   1576 N NE1 . TRP A 1 202 ? -17.27634 7.83293   2.58470  1.000 45.83106 ? 229 TRP A NE1 1 
ATOM   1577 C CE2 . TRP A 1 202 ? -17.15002 6.61260   3.20018  1.000 54.59373 ? 229 TRP A CE2 1 
ATOM   1578 C CE3 . TRP A 1 202 ? -15.75905 5.58572   4.88977  1.000 47.81302 ? 229 TRP A CE3 1 
ATOM   1579 C CZ2 . TRP A 1 202 ? -17.87522 5.43483   3.02290  1.000 46.88891 ? 229 TRP A CZ2 1 
ATOM   1580 C CZ3 . TRP A 1 202 ? -16.48868 4.41933   4.72026  1.000 39.18501 ? 229 TRP A CZ3 1 
ATOM   1581 C CH2 . TRP A 1 202 ? -17.53153 4.35532   3.78796  1.000 45.27930 ? 229 TRP A CH2 1 
ATOM   1582 N N   . THR A 1 203 ? -13.77924 11.14428  6.82397  1.000 43.00962 ? 230 THR A N   1 
ATOM   1583 C CA  . THR A 1 203 ? -12.92187 11.57851  7.91367  1.000 36.21059 ? 230 THR A CA  1 
ATOM   1584 C C   . THR A 1 203 ? -12.71863 10.40171  8.86083  1.000 35.23621 ? 230 THR A C   1 
ATOM   1585 O O   . THR A 1 203 ? -13.67862 9.70610   9.21616  1.000 34.45739 ? 230 THR A O   1 
ATOM   1586 C CB  . THR A 1 203 ? -13.52763 12.76881  8.64977  1.000 38.90639 ? 230 THR A CB  1 
ATOM   1587 O OG1 . THR A 1 203 ? -13.70140 13.83215  7.70826  1.000 48.85866 ? 230 THR A OG1 1 
ATOM   1588 C CG2 . THR A 1 203 ? -12.60827 13.24183  9.75750  1.000 40.80570 ? 230 THR A CG2 1 
ATOM   1589 N N   . VAL A 1 204 ? -11.46866 10.16246  9.23339  1.000 34.27905 ? 231 VAL A N   1 
ATOM   1590 C CA  . VAL A 1 204 ? -11.11234 9.03018   10.08504 1.000 29.99667 ? 231 VAL A CA  1 
ATOM   1591 C C   . VAL A 1 204 ? -10.31054 9.53871   11.27386 1.000 30.70598 ? 231 VAL A C   1 
ATOM   1592 O O   . VAL A 1 204 ? -9.46000  10.41978  11.11761 1.000 33.90753 ? 231 VAL A O   1 
ATOM   1593 C CB  . VAL A 1 204 ? -10.30147 7.99017   9.28939  1.000 32.59726 ? 231 VAL A CB  1 
ATOM   1594 C CG1 . VAL A 1 204 ? -9.92186  6.81703   10.17423 1.000 27.34818 ? 231 VAL A CG1 1 
ATOM   1595 C CG2 . VAL A 1 204 ? -11.08616 7.53523   8.08322  1.000 40.62258 ? 231 VAL A CG2 1 
ATOM   1596 N N   . GLY A 1 205 ? -10.56563 8.96826   12.45863 1.000 25.81556 ? 232 GLY A N   1 
ATOM   1597 C CA  . GLY A 1 205 ? -9.69260  9.16349   13.60516 1.000 24.98189 ? 232 GLY A CA  1 
ATOM   1598 C C   . GLY A 1 205 ? -9.27220  7.75479   13.99544 1.000 24.37414 ? 232 GLY A C   1 
ATOM   1599 O O   . GLY A 1 205 ? -10.14238 6.88413   14.08719 1.000 28.07062 ? 232 GLY A O   1 
ATOM   1600 N N   . ASP A 1 206 ? -7.98469  7.48935   14.20332 1.000 23.75940 ? 233 ASP A N   1 
ATOM   1601 C CA  . ASP A 1 206 ? -7.58402  6.10100   14.41141 1.000 22.92736 ? 233 ASP A CA  1 
ATOM   1602 C C   . ASP A 1 206 ? -6.37294  6.04426   15.32628 1.000 25.31292 ? 233 ASP A C   1 
ATOM   1603 O O   . ASP A 1 206 ? -5.69137  7.04751   15.53769 1.000 23.44954 ? 233 ASP A O   1 
ATOM   1604 C CB  . ASP A 1 206 ? -7.25531  5.40438   13.06929 1.000 22.25709 ? 233 ASP A CB  1 
ATOM   1605 C CG  . ASP A 1 206 ? -5.85479  5.72360   12.56376 1.000 23.36749 ? 233 ASP A CG  1 
ATOM   1606 O OD1 . ASP A 1 206 ? -5.60502  6.88288   12.21733 1.000 24.89800 ? 233 ASP A OD1 1 
ATOM   1607 O OD2 . ASP A 1 206 ? -4.95775  4.83197   12.54334 1.000 22.74579 ? 233 ASP A OD2 1 
ATOM   1608 N N   . LYS A 1 207 ? -6.10749  4.84575   15.87091 1.000 18.43467 ? 234 LYS A N   1 
ATOM   1609 C CA  . LYS A 1 207 ? -4.88215  4.57394   16.59767 1.000 17.60605 ? 234 LYS A CA  1 
ATOM   1610 C C   . LYS A 1 207 ? -4.34285  3.25440   16.07508 1.000 16.59826 ? 234 LYS A C   1 
ATOM   1611 O O   . LYS A 1 207 ? -5.02733  2.23011   16.16856 1.000 18.98804 ? 234 LYS A O   1 
ATOM   1612 C CB  . LYS A 1 207 ? -5.09657  4.44160   18.11173 1.000 16.93790 ? 234 LYS A CB  1 
ATOM   1613 C CG  . LYS A 1 207 ? -3.79845  4.08440   18.84717 1.000 16.54043 ? 234 LYS A CG  1 
ATOM   1614 C CD  . LYS A 1 207 ? -2.84502  5.34478   18.94980 1.000 19.82484 ? 234 LYS A CD  1 
ATOM   1615 C CE  . LYS A 1 207 ? -1.44925  4.90272   19.43151 1.000 18.44508 ? 234 LYS A CE  1 
ATOM   1616 N NZ  . LYS A 1 207 ? -0.70262  4.40602   18.19508 1.000 19.96425 ? 234 LYS A NZ  1 
ATOM   1617 N N   . THR A 1 208 ? -3.10707  3.26647   15.56525 1.000 17.90203 ? 235 THR A N   1 
ATOM   1618 C CA  . THR A 1 208 ? -2.45406  2.04650   15.11676 1.000 16.95336 ? 235 THR A CA  1 
ATOM   1619 C C   . THR A 1 208 ? -1.76793  1.31787   16.25272 1.000 17.58746 ? 235 THR A C   1 
ATOM   1620 O O   . THR A 1 208 ? -1.61599  1.82167   17.37824 1.000 18.43568 ? 235 THR A O   1 
ATOM   1621 C CB  . THR A 1 208 ? -1.39489  2.38933   14.06102 1.000 20.58468 ? 235 THR A CB  1 
ATOM   1622 O OG1 . THR A 1 208 ? -0.50427  3.37691   14.63908 1.000 22.27666 ? 235 THR A OG1 1 
ATOM   1623 C CG2 . THR A 1 208 ? -2.05318  2.98262   12.81357 1.000 21.69108 ? 235 THR A CG2 1 
ATOM   1624 N N   . GLY A 1 209 ? -1.34064  0.09562   15.95698 1.000 16.46900 ? 236 GLY A N   1 
ATOM   1625 C CA  . GLY A 1 209 ? -0.48604  -0.62677  16.88041 1.000 18.66574 ? 236 GLY A CA  1 
ATOM   1626 C C   . GLY A 1 209 ? 0.30041   -1.68703  16.15052 1.000 20.35961 ? 236 GLY A C   1 
ATOM   1627 O O   . GLY A 1 209 ? -0.14573  -2.24262  15.13035 1.000 19.31525 ? 236 GLY A O   1 
ATOM   1628 N N   . SER A 1 210 ? 1.50532   -1.94468  16.64473 1.000 19.34064 ? 237 SER A N   1 
ATOM   1629 C CA  . SER A 1 210 ? 2.33728   -2.96371  16.02699 1.000 14.93667 ? 237 SER A CA  1 
ATOM   1630 C C   . SER A 1 210 ? 3.24310   -3.57715  17.07995 1.000 19.22254 ? 237 SER A C   1 
ATOM   1631 O O   . SER A 1 210 ? 3.51277   -2.97608  18.12478 1.000 18.99882 ? 237 SER A O   1 
ATOM   1632 C CB  . SER A 1 210 ? 3.14612   -2.42738  14.85391 1.000 24.96940 ? 237 SER A CB  1 
ATOM   1633 O OG  . SER A 1 210 ? 4.03469   -1.43197  15.27943 1.000 27.31858 ? 237 SER A OG  1 
ATOM   1634 N N   . GLY A 1 211 ? 3.66621   -4.80338  16.82039 1.000 19.20867 ? 238 GLY A N   1 
ATOM   1635 C CA  . GLY A 1 211 ? 4.46883   -5.49951  17.81027 1.000 17.20640 ? 238 GLY A CA  1 
ATOM   1636 C C   . GLY A 1 211 ? 5.09628   -6.73390  17.22071 1.000 22.04833 ? 238 GLY A C   1 
ATOM   1637 O O   . GLY A 1 211 ? 5.11607   -6.93196  16.00126 1.000 19.11117 ? 238 GLY A O   1 
ATOM   1638 N N   . ASP A 1 212 ? 5.61641   -7.58133  18.11018 1.000 17.21981 ? 239 ASP A N   1 
ATOM   1639 C CA  . ASP A 1 212 ? 6.23654   -8.81997  17.66543 1.000 19.73533 ? 239 ASP A CA  1 
ATOM   1640 C C   . ASP A 1 212 ? 5.19212   -9.73537  17.00567 1.000 18.56008 ? 239 ASP A C   1 
ATOM   1641 O O   . ASP A 1 212 ? 3.99741   -9.44303  16.97978 1.000 18.15801 ? 239 ASP A O   1 
ATOM   1642 C CB  . ASP A 1 212 ? 6.91349   -9.52784  18.85122 1.000 18.31485 ? 239 ASP A CB  1 
ATOM   1643 C CG  . ASP A 1 212 ? 8.18142   -8.81612  19.30358 1.000 34.81829 ? 239 ASP A CG  1 
ATOM   1644 O OD1 . ASP A 1 212 ? 8.63436   -7.85844  18.61613 1.000 31.31479 ? 239 ASP A OD1 1 
ATOM   1645 O OD2 . ASP A 1 212 ? 8.71957   -9.22428  20.36012 1.000 37.71506 ? 239 ASP A OD2 1 
ATOM   1646 N N   . TYR A 1 213 ? 5.66081   -10.85242 16.45456 1.000 16.44843 ? 240 TYR A N   1 
ATOM   1647 C CA  . TYR A 1 213 ? 4.78936   -11.76735 15.67117 1.000 20.03960 ? 240 TYR A CA  1 
ATOM   1648 C C   . TYR A 1 213 ? 4.05261   -11.03250 14.53802 1.000 16.49664 ? 240 TYR A C   1 
ATOM   1649 O O   . TYR A 1 213 ? 2.94265   -11.40471 14.16447 1.000 17.85949 ? 240 TYR A O   1 
ATOM   1650 C CB  . TYR A 1 213 ? 3.80146   -12.52386 16.57725 1.000 16.56192 ? 240 TYR A CB  1 
ATOM   1651 C CG  . TYR A 1 213 ? 4.58380   -13.58640 17.34820 1.000 16.90399 ? 240 TYR A CG  1 
ATOM   1652 C CD1 . TYR A 1 213 ? 5.19953   -13.25864 18.54191 1.000 18.90748 ? 240 TYR A CD1 1 
ATOM   1653 C CD2 . TYR A 1 213 ? 4.73501   -14.87664 16.82798 1.000 22.79560 ? 240 TYR A CD2 1 
ATOM   1654 C CE1 . TYR A 1 213 ? 5.97223   -14.18503 19.23969 1.000 21.55168 ? 240 TYR A CE1 1 
ATOM   1655 C CE2 . TYR A 1 213 ? 5.50999   -15.82829 17.50948 1.000 25.03974 ? 240 TYR A CE2 1 
ATOM   1656 C CZ  . TYR A 1 213 ? 6.12580   -15.45425 18.72366 1.000 23.71609 ? 240 TYR A CZ  1 
ATOM   1657 O OH  . TYR A 1 213 ? 6.87288   -16.38068 19.42087 1.000 25.38708 ? 240 TYR A OH  1 
ATOM   1658 N N   . GLY A 1 214 ? 4.69598   -10.00159 13.97771 1.000 18.18645 ? 241 GLY A N   1 
ATOM   1659 C CA  . GLY A 1 214 ? 4.09445   -9.26761  12.85956 1.000 17.37530 ? 241 GLY A CA  1 
ATOM   1660 C C   . GLY A 1 214 ? 2.74660   -8.66718  13.19933 1.000 18.53330 ? 241 GLY A C   1 
ATOM   1661 O O   . GLY A 1 214 ? 1.89045   -8.46456  12.30712 1.000 17.72288 ? 241 GLY A O   1 
ATOM   1662 N N   . THR A 1 215 ? 2.52445   -8.35906  14.46867 1.000 14.68864 ? 242 THR A N   1 
ATOM   1663 C CA  . THR A 1 215 ? 1.22126   -7.88945  14.88055 1.000 13.20965 ? 242 THR A CA  1 
ATOM   1664 C C   . THR A 1 215 ? 1.00386   -6.48940  14.32935 1.000 14.60787 ? 242 THR A C   1 
ATOM   1665 O O   . THR A 1 215 ? 1.87270   -5.62198  14.45444 1.000 15.77126 ? 242 THR A O   1 
ATOM   1666 C CB  . THR A 1 215 ? 1.12376   -7.91993  16.43054 1.000 15.06789 ? 242 THR A CB  1 
ATOM   1667 O OG1 . THR A 1 215 ? 1.23558   -9.30776  16.84351 1.000 15.70006 ? 242 THR A OG1 1 
ATOM   1668 C CG2 . THR A 1 215 ? -0.20802  -7.32052  16.91621 1.000 14.90120 ? 242 THR A CG2 1 
ATOM   1669 N N   . THR A 1 216 ? -0.14595  -6.28606  13.69261 1.000 13.39613 ? 243 THR A N   1 
ATOM   1670 C CA  . THR A 1 216 ? -0.41068  -5.05854  12.92382 1.000 11.81059 ? 243 THR A CA  1 
ATOM   1671 C C   . THR A 1 216 ? -1.87481  -4.72951  13.18159 1.000 15.27728 ? 243 THR A C   1 
ATOM   1672 O O   . THR A 1 216 ? -2.74102  -5.47497  12.72290 1.000 14.70594 ? 243 THR A O   1 
ATOM   1673 C CB  . THR A 1 216 ? -0.17264  -5.25975  11.41794 1.000 17.43184 ? 243 THR A CB  1 
ATOM   1674 O OG1 . THR A 1 216 ? 1.09939   -5.89965  11.20113 1.000 18.13759 ? 243 THR A OG1 1 
ATOM   1675 C CG2 . THR A 1 216 ? -0.21538  -3.91945  10.70294 1.000 18.51859 ? 243 THR A CG2 1 
ATOM   1676 N N   . ASN A 1 217 ? -2.15171  -3.62479  13.89664 1.000 13.35096 ? 244 ASN A N   1 
ATOM   1677 C CA  . ASN A 1 217 ? -3.49587  -3.31547  14.37544 1.000 15.51345 ? 244 ASN A CA  1 
ATOM   1678 C C   . ASN A 1 217 ? -3.89432  -1.89413  14.00491 1.000 15.42362 ? 244 ASN A C   1 
ATOM   1679 O O   . ASN A 1 217 ? -3.03816  -1.01974  13.79802 1.000 15.78942 ? 244 ASN A O   1 
ATOM   1680 C CB  . ASN A 1 217 ? -3.56448  -3.39871  15.90764 1.000 14.43201 ? 244 ASN A CB  1 
ATOM   1681 C CG  . ASN A 1 217 ? -3.19450  -4.75982  16.44623 1.000 17.11844 ? 244 ASN A CG  1 
ATOM   1682 O OD1 . ASN A 1 217 ? -3.38777  -5.77707  15.79439 1.000 15.36414 ? 244 ASN A OD1 1 
ATOM   1683 N ND2 . ASN A 1 217 ? -2.70141  -4.78426  17.68663 1.000 15.55323 ? 244 ASN A ND2 1 
ATOM   1684 N N   . ASP A 1 218 ? -5.20667  -1.62908  13.96751 1.000 14.50189 ? 245 ASP A N   1 
ATOM   1685 C CA  . ASP A 1 218 ? -5.65792  -0.24265  13.81462 1.000 15.14082 ? 245 ASP A CA  1 
ATOM   1686 C C   . ASP A 1 218 ? -7.09004  -0.19512  14.32720 1.000 20.85256 ? 245 ASP A C   1 
ATOM   1687 O O   . ASP A 1 218 ? -7.87335  -1.12439  14.07957 1.000 18.11375 ? 245 ASP A O   1 
ATOM   1688 C CB  . ASP A 1 218 ? -5.57475  0.19027   12.32676 1.000 16.19917 ? 245 ASP A CB  1 
ATOM   1689 C CG  . ASP A 1 218 ? -5.65362  1.71168   12.11511 1.000 18.81884 ? 245 ASP A CG  1 
ATOM   1690 O OD1 . ASP A 1 218 ? -5.52404  2.48098   13.09861 1.000 17.61393 ? 245 ASP A OD1 1 
ATOM   1691 O OD2 . ASP A 1 218 ? -5.81694  2.13287   10.95054 1.000 21.29425 ? 245 ASP A OD2 1 
ATOM   1692 N N   . ILE A 1 219 ? -7.41340  0.82094   15.10818 1.000 17.32766 ? 246 ILE A N   1 
ATOM   1693 C CA  . ILE A 1 219 ? -8.79626  1.00401   15.53234 1.000 18.83255 ? 246 ILE A CA  1 
ATOM   1694 C C   . ILE A 1 219 ? -9.22590  2.39138   15.11317 1.000 20.63513 ? 246 ILE A C   1 
ATOM   1695 O O   . ILE A 1 219 ? -8.43942  3.34214   15.19502 1.000 21.44741 ? 246 ILE A O   1 
ATOM   1696 C CB  . ILE A 1 219 ? -8.97403  0.77035   17.05235 1.000 16.54613 ? 246 ILE A CB  1 
ATOM   1697 C CG1 . ILE A 1 219 ? -8.21904  1.80609   17.90395 1.000 19.24638 ? 246 ILE A CG1 1 
ATOM   1698 C CG2 . ILE A 1 219 ? -8.44665  -0.63231  17.39790 1.000 15.84311 ? 246 ILE A CG2 1 
ATOM   1699 C CD1 . ILE A 1 219 ? -8.43319  1.61158   19.48623 1.000 19.29103 ? 246 ILE A CD1 1 
ATOM   1700 N N   . ALA A 1 220 ? -10.45559 2.49993   14.60508 1.000 19.84701 ? 247 ALA A N   1 
ATOM   1701 C CA  . ALA A 1 220 ? -10.84589 3.76735   13.99770 1.000 20.10116 ? 247 ALA A CA  1 
ATOM   1702 C C   . ALA A 1 220 ? -12.31496 4.09128   14.23590 1.000 25.39492 ? 247 ALA A C   1 
ATOM   1703 O O   . ALA A 1 220 ? -13.16606 3.20606   14.38861 1.000 24.87762 ? 247 ALA A O   1 
ATOM   1704 C CB  . ALA A 1 220 ? -10.57729 3.77724   12.48563 1.000 21.82504 ? 247 ALA A CB  1 
ATOM   1705 N N   A VAL A 1 221 ? -12.58373 5.38677   14.30369 0.565 23.98166 ? 248 VAL A N   1 
ATOM   1706 N N   B VAL A 1 221 ? -12.59310 5.38449   14.28466 0.435 23.99410 ? 248 VAL A N   1 
ATOM   1707 C CA  A VAL A 1 221 ? -13.92480 5.93936   14.17825 0.565 23.65737 ? 248 VAL A CA  1 
ATOM   1708 C CA  B VAL A 1 221 ? -13.94525 5.91096   14.18086 0.435 23.64289 ? 248 VAL A CA  1 
ATOM   1709 C C   A VAL A 1 221 ? -13.97739 6.63801   12.82696 0.565 25.04794 ? 248 VAL A C   1 
ATOM   1710 C C   B VAL A 1 221 ? -14.01259 6.67639   12.86456 0.435 25.08625 ? 248 VAL A C   1 
ATOM   1711 O O   A VAL A 1 221 ? -13.02835 7.33547   12.44389 0.565 28.65681 ? 248 VAL A O   1 
ATOM   1712 O O   B VAL A 1 221 ? -13.09705 7.44352   12.53672 0.435 28.65121 ? 248 VAL A O   1 
ATOM   1713 C CB  A VAL A 1 221 ? -14.25768 6.91450   15.32208 0.565 26.94607 ? 248 VAL A CB  1 
ATOM   1714 C CB  B VAL A 1 221 ? -14.30551 6.79353   15.38819 0.435 26.98898 ? 248 VAL A CB  1 
ATOM   1715 C CG1 A VAL A 1 221 ? -15.72449 7.33829   15.26790 0.565 29.35507 ? 248 VAL A CG1 1 
ATOM   1716 C CG1 B VAL A 1 221 ? -13.19535 7.78470   15.67841 0.435 25.05320 ? 248 VAL A CG1 1 
ATOM   1717 C CG2 A VAL A 1 221 ? -13.96284 6.27228   16.64134 0.565 22.90019 ? 248 VAL A CG2 1 
ATOM   1718 C CG2 B VAL A 1 221 ? -15.63948 7.50381   15.16526 0.435 29.52974 ? 248 VAL A CG2 1 
ATOM   1719 N N   . ILE A 1 222 ? -15.06596 6.43373   12.08918 1.000 27.57027 ? 249 ILE A N   1 
ATOM   1720 C CA  . ILE A 1 222 ? -15.15147 6.87435   10.70320 1.000 29.30733 ? 249 ILE A CA  1 
ATOM   1721 C C   . ILE A 1 222 ? -16.41202 7.69244   10.54054 1.000 32.99196 ? 249 ILE A C   1 
ATOM   1722 O O   . ILE A 1 222 ? -17.48648 7.25808   10.96726 1.000 33.51125 ? 249 ILE A O   1 
ATOM   1723 C CB  . ILE A 1 222 ? -15.16881 5.67482   9.73158  1.000 32.07867 ? 249 ILE A CB  1 
ATOM   1724 C CG1 . ILE A 1 222 ? -13.96814 4.75510   9.98186  1.000 32.17203 ? 249 ILE A CG1 1 
ATOM   1725 C CG2 . ILE A 1 222 ? -15.21529 6.17710   8.25695  1.000 31.20573 ? 249 ILE A CG2 1 
ATOM   1726 C CD1 . ILE A 1 222 ? -14.17985 3.33304   9.48163  1.000 32.36633 ? 249 ILE A CD1 1 
ATOM   1727 N N   . TRP A 1 223 ? -16.27065 8.87377   9.93784  1.000 35.89747 ? 250 TRP A N   1 
ATOM   1728 C CA  . TRP A 1 223 ? -17.38213 9.77191   9.63841  1.000 32.62309 ? 250 TRP A CA  1 
ATOM   1729 C C   . TRP A 1 223 ? -17.52171 9.86156   8.12491  1.000 38.75474 ? 250 TRP A C   1 
ATOM   1730 O O   . TRP A 1 223 ? -16.81874 10.65525  7.47874  1.000 37.00723 ? 250 TRP A O   1 
ATOM   1731 C CB  . TRP A 1 223 ? -17.13753 11.15458  10.24206 1.000 34.03314 ? 250 TRP A CB  1 
ATOM   1732 C CG  . TRP A 1 223 ? -17.17889 11.21332  11.70292 1.000 41.71819 ? 250 TRP A CG  1 
ATOM   1733 C CD1 . TRP A 1 223 ? -18.25841 11.49891  12.48798 1.000 38.51628 ? 250 TRP A CD1 1 
ATOM   1734 C CD2 . TRP A 1 223 ? -16.07129 11.02470  12.58896 1.000 40.65466 ? 250 TRP A CD2 1 
ATOM   1735 N NE1 . TRP A 1 223 ? -17.89646 11.48067  13.81749 1.000 39.85714 ? 250 TRP A NE1 1 
ATOM   1736 C CE2 . TRP A 1 223 ? -16.55658 11.19457  13.90362 1.000 42.04589 ? 250 TRP A CE2 1 
ATOM   1737 C CE3 . TRP A 1 223 ? -14.71079 10.71739  12.39785 1.000 37.56960 ? 250 TRP A CE3 1 
ATOM   1738 C CZ2 . TRP A 1 223 ? -15.73681 11.07065  15.01476 1.000 37.29122 ? 250 TRP A CZ2 1 
ATOM   1739 C CZ3 . TRP A 1 223 ? -13.89669 10.60096  13.51581 1.000 38.48042 ? 250 TRP A CZ3 1 
ATOM   1740 C CH2 . TRP A 1 223 ? -14.41181 10.78203  14.79906 1.000 36.44459 ? 250 TRP A CH2 1 
ATOM   1741 N N   . PRO A 1 224 ? -18.35125 9.02337   7.50805  1.000 45.92958 ? 251 PRO A N   1 
ATOM   1742 C CA  . PRO A 1 224 ? -18.61587 9.17744   6.07142  1.000 48.98011 ? 251 PRO A CA  1 
ATOM   1743 C C   . PRO A 1 224 ? -19.41185 10.44459  5.83957  1.000 54.71229 ? 251 PRO A C   1 
ATOM   1744 O O   . PRO A 1 224 ? -20.10745 10.93731  6.73093  1.000 54.87306 ? 251 PRO A O   1 
ATOM   1745 C CB  . PRO A 1 224 ? -19.44092 7.93260   5.71721  1.000 54.31374 ? 251 PRO A CB  1 
ATOM   1746 C CG  . PRO A 1 224 ? -19.27588 6.98743   6.90617  1.000 50.55461 ? 251 PRO A CG  1 
ATOM   1747 C CD  . PRO A 1 224 ? -19.12145 7.90901   8.08245  1.000 44.02582 ? 251 PRO A CD  1 
ATOM   1748 N N   . GLN A 1 225 ? -19.29181 10.97475  4.62360  1.000 64.21566 ? 252 GLN A N   1 
ATOM   1749 C CA  . GLN A 1 225 ? -20.04325 12.16483  4.24371  1.000 76.56376 ? 252 GLN A CA  1 
ATOM   1750 C C   . GLN A 1 225 ? -21.53343 11.85110  4.17989  1.000 67.63038 ? 252 GLN A C   1 
ATOM   1751 O O   . GLN A 1 225 ? -21.94910 10.88864  3.52578  1.000 63.62852 ? 252 GLN A O   1 
ATOM   1752 C CB  . GLN A 1 225 ? -19.56145 12.68824  2.89304  1.000 63.28753 ? 252 GLN A CB  1 
ATOM   1753 C CG  . GLN A 1 225 ? -18.10797 13.11360  2.85683  1.000 77.54690 ? 252 GLN A CG  1 
ATOM   1754 C CD  . GLN A 1 225 ? -17.89354 14.47288  3.47080  1.000 80.66433 ? 252 GLN A CD  1 
ATOM   1755 O OE1 . GLN A 1 225 ? -18.47692 15.46553  3.02547  1.000 79.79452 ? 252 GLN A OE1 1 
ATOM   1756 N NE2 . GLN A 1 225 ? -17.05752 14.53010  4.50628  1.000 91.73016 ? 252 GLN A NE2 1 
ATOM   1757 N N   . GLY A 1 226 ? -22.33373 12.66698  4.86398  1.000 71.99510 ? 253 GLY A N   1 
ATOM   1758 C CA  . GLY A 1 226 ? -23.77458 12.49708  4.89364  1.000 66.82921 ? 253 GLY A CA  1 
ATOM   1759 C C   . GLY A 1 226 ? -24.22173 11.08811  5.22123  1.000 71.32126 ? 253 GLY A C   1 
ATOM   1760 O O   . GLY A 1 226 ? -25.01096 10.48795  4.48629  1.000 65.31981 ? 253 GLY A O   1 
ATOM   1761 N N   . ARG A 1 227 ? -23.71218 10.54435  6.32075  1.000 65.80231 ? 254 ARG A N   1 
ATOM   1762 C CA  . ARG A 1 227 ? -24.02230 9.18019   6.71557  1.000 59.91088 ? 254 ARG A CA  1 
ATOM   1763 C C   . ARG A 1 227 ? -23.51619 8.98687   8.13768  1.000 49.96119 ? 254 ARG A C   1 
ATOM   1764 O O   . ARG A 1 227 ? -22.52900 9.60671   8.53405  1.000 56.93401 ? 254 ARG A O   1 
ATOM   1765 C CB  . ARG A 1 227 ? -23.37327 8.16733   5.76880  1.000 66.41496 ? 254 ARG A CB  1 
ATOM   1766 C CG  . ARG A 1 227 ? -23.94132 6.78716   5.88346  1.000 59.62825 ? 254 ARG A CG  1 
ATOM   1767 C CD  . ARG A 1 227 ? -22.84379 5.75341   5.95047  1.000 54.23078 ? 254 ARG A CD  1 
ATOM   1768 N NE  . ARG A 1 227 ? -23.40570 4.40959   5.98666  1.000 54.94640 ? 254 ARG A NE  1 
ATOM   1769 C CZ  . ARG A 1 227 ? -23.71471 3.75079   7.09663  1.000 66.76584 ? 254 ARG A CZ  1 
ATOM   1770 N NH1 . ARG A 1 227 ? -23.46731 4.25822   8.30284  1.000 52.43003 ? 254 ARG A NH1 1 
ATOM   1771 N NH2 . ARG A 1 227 ? -24.28920 2.55398   6.99597  1.000 68.90245 ? 254 ARG A NH2 1 
ATOM   1772 N N   . ALA A 1 228 ? -24.22142 8.15521   8.90052  1.000 48.92686 ? 255 ALA A N   1 
ATOM   1773 C CA  . ALA A 1 228 ? -23.90454 7.98141   10.31101 1.000 51.72082 ? 255 ALA A CA  1 
ATOM   1774 C C   . ALA A 1 228 ? -22.49255 7.41972   10.46839 1.000 44.87216 ? 255 ALA A C   1 
ATOM   1775 O O   . ALA A 1 228 ? -22.01120 6.68448   9.60393  1.000 44.45182 ? 255 ALA A O   1 
ATOM   1776 C CB  . ALA A 1 228 ? -24.90867 7.04701   10.98169 1.000 48.81071 ? 255 ALA A CB  1 
ATOM   1777 N N   . PRO A 1 229 ? -21.80551 7.75224   11.55934 1.000 44.06268 ? 256 PRO A N   1 
ATOM   1778 C CA  . PRO A 1 229 ? -20.44214 7.24998   11.74406 1.000 41.73583 ? 256 PRO A CA  1 
ATOM   1779 C C   . PRO A 1 229 ? -20.38393 5.74663   11.96283 1.000 40.88069 ? 256 PRO A C   1 
ATOM   1780 O O   . PRO A 1 229 ? -21.35328 5.07981   12.33587 1.000 39.49998 ? 256 PRO A O   1 
ATOM   1781 C CB  . PRO A 1 229 ? -19.93870 8.00628   12.98149 1.000 41.95927 ? 256 PRO A CB  1 
ATOM   1782 C CG  . PRO A 1 229 ? -21.14987 8.55582   13.64249 1.000 51.07156 ? 256 PRO A CG  1 
ATOM   1783 C CD  . PRO A 1 229 ? -22.12113 8.81965   12.53052 1.000 45.78440 ? 256 PRO A CD  1 
ATOM   1784 N N   . LEU A 1 230 ? -19.18928 5.22159   11.72551 1.000 37.53633 ? 257 LEU A N   1 
ATOM   1785 C CA  . LEU A 1 230 ? -18.88947 3.81609   11.91493 1.000 35.35161 ? 257 LEU A CA  1 
ATOM   1786 C C   . LEU A 1 230 ? -17.69682 3.70114   12.85077 1.000 33.51232 ? 257 LEU A C   1 
ATOM   1787 O O   . LEU A 1 230 ? -16.86330 4.60277   12.91535 1.000 34.07234 ? 257 LEU A O   1 
ATOM   1788 C CB  . LEU A 1 230 ? -18.53491 3.12299   10.59179 1.000 35.00015 ? 257 LEU A CB  1 
ATOM   1789 C CG  . LEU A 1 230 ? -19.35826 3.43425   9.33873  1.000 37.41613 ? 257 LEU A CG  1 
ATOM   1790 C CD1 . LEU A 1 230 ? -18.52031 3.05245   8.15095  1.000 44.25115 ? 257 LEU A CD1 1 
ATOM   1791 C CD2 . LEU A 1 230 ? -20.64666 2.65128   9.34589  1.000 44.09204 ? 257 LEU A CD2 1 
ATOM   1792 N N   . VAL A 1 231 ? -17.62440 2.58315   13.56001 1.000 31.84961 ? 258 VAL A N   1 
ATOM   1793 C CA  . VAL A 1 231 ? -16.44694 2.22267   14.35404 1.000 29.93853 ? 258 VAL A CA  1 
ATOM   1794 C C   . VAL A 1 231 ? -15.89780 0.92300   13.78226 1.000 28.18920 ? 258 VAL A C   1 
ATOM   1795 O O   . VAL A 1 231 ? -16.65664 -0.02696  13.57469 1.000 28.31319 ? 258 VAL A O   1 
ATOM   1796 C CB  . VAL A 1 231 ? -16.79974 2.06450   15.84112 1.000 29.86756 ? 258 VAL A CB  1 
ATOM   1797 C CG1 . VAL A 1 231 ? -15.55319 1.74555   16.66616 1.000 32.23579 ? 258 VAL A CG1 1 
ATOM   1798 C CG2 . VAL A 1 231 ? -17.46389 3.35700   16.34300 1.000 32.13047 ? 258 VAL A CG2 1 
ATOM   1799 N N   . LEU A 1 232 ? -14.58861 0.87518   13.52363 1.000 26.94508 ? 259 LEU A N   1 
ATOM   1800 C CA  . LEU A 1 232 ? -14.00283 -0.28718  12.86697 1.000 25.62512 ? 259 LEU A CA  1 
ATOM   1801 C C   . LEU A 1 232 ? -12.71494 -0.63797  13.57925 1.000 24.53694 ? 259 LEU A C   1 
ATOM   1802 O O   . LEU A 1 232 ? -11.85214 0.22433   13.72693 1.000 23.76488 ? 259 LEU A O   1 
ATOM   1803 C CB  . LEU A 1 232 ? -13.70408 -0.00502  11.39044 1.000 26.62256 ? 259 LEU A CB  1 
ATOM   1804 C CG  . LEU A 1 232 ? -12.95157 -1.11974  10.63390 1.000 25.67186 ? 259 LEU A CG  1 
ATOM   1805 C CD1 . LEU A 1 232 ? -13.76432 -2.38068  10.60704 1.000 26.56518 ? 259 LEU A CD1 1 
ATOM   1806 C CD2 . LEU A 1 232 ? -12.67758 -0.63267  9.20000  1.000 27.50954 ? 259 LEU A CD2 1 
ATOM   1807 N N   A VAL A 1 233 ? -12.60368 -1.89026  14.02583 0.586 22.33825 ? 260 VAL A N   1 
ATOM   1808 N N   B VAL A 1 233 ? -12.58291 -1.88525  14.01841 0.414 22.32633 ? 260 VAL A N   1 
ATOM   1809 C CA  A VAL A 1 233 ? -11.41210 -2.42600  14.66384 0.586 20.52110 ? 260 VAL A CA  1 
ATOM   1810 C CA  B VAL A 1 233 ? -11.35897 -2.35840  14.64090 0.414 20.53550 ? 260 VAL A CA  1 
ATOM   1811 C C   A VAL A 1 233 ? -10.85284 -3.52433  13.76154 0.586 21.45457 ? 260 VAL A C   1 
ATOM   1812 C C   B VAL A 1 233 ? -10.83273 -3.52522  13.80920 0.414 21.40335 ? 260 VAL A C   1 
ATOM   1813 O O   A VAL A 1 233 ? -11.61545 -4.37359  13.27797 0.586 21.24003 ? 260 VAL A O   1 
ATOM   1814 O O   B VAL A 1 233 ? -11.60474 -4.39693  13.38621 0.414 21.17094 ? 260 VAL A O   1 
ATOM   1815 C CB  A VAL A 1 233 ? -11.75128 -2.97025  16.06117 0.586 20.76556 ? 260 VAL A CB  1 
ATOM   1816 C CB  B VAL A 1 233 ? -11.60296 -2.72510  16.11531 0.414 20.28317 ? 260 VAL A CB  1 
ATOM   1817 C CG1 A VAL A 1 233 ? -10.69187 -3.91166  16.50035 0.586 18.59270 ? 260 VAL A CG1 1 
ATOM   1818 C CG1 B VAL A 1 233 ? -12.32741 -1.55933  16.79384 0.414 21.46771 ? 260 VAL A CG1 1 
ATOM   1819 C CG2 A VAL A 1 233 ? -11.93928 -1.82993  17.05270 0.586 25.10309 ? 260 VAL A CG2 1 
ATOM   1820 C CG2 B VAL A 1 233 ? -12.42853 -3.98039  16.22775 0.414 21.58504 ? 260 VAL A CG2 1 
ATOM   1821 N N   . THR A 1 234 ? -9.53640  -3.48201  13.49575 1.000 18.81879 ? 261 THR A N   1 
ATOM   1822 C CA  . THR A 1 234 ? -8.86729  -4.49605  12.67031 1.000 18.27387 ? 261 THR A CA  1 
ATOM   1823 C C   . THR A 1 234 ? -7.60155  -4.91786  13.40304 1.000 24.12634 ? 261 THR A C   1 
ATOM   1824 O O   . THR A 1 234 ? -6.70583  -4.09784  13.62766 1.000 20.54460 ? 261 THR A O   1 
ATOM   1825 C CB  . THR A 1 234 ? -8.51354  -4.01008  11.24718 1.000 22.30767 ? 261 THR A CB  1 
ATOM   1826 O OG1 . THR A 1 234 ? -7.67981  -2.83847  11.29997 1.000 22.23257 ? 261 THR A OG1 1 
ATOM   1827 C CG2 . THR A 1 234 ? -9.77767  -3.70259  10.37941 1.000 25.81971 ? 261 THR A CG2 1 
ATOM   1828 N N   A TYR A 1 235 ? -7.53986  -6.17909  13.81204 0.547 16.53915 ? 262 TYR A N   1 
ATOM   1829 N N   B TYR A 1 235 ? -7.53692  -6.17841  13.79959 0.453 16.55500 ? 262 TYR A N   1 
ATOM   1830 C CA  A TYR A 1 235 ? -6.36759  -6.73341  14.47464 0.547 16.72516 ? 262 TYR A CA  1 
ATOM   1831 C CA  B TYR A 1 235 ? -6.36069  -6.72408  14.45536 0.453 16.70359 ? 262 TYR A CA  1 
ATOM   1832 C C   A TYR A 1 235 ? -5.78157  -7.84651  13.61185 0.547 18.70872 ? 262 TYR A C   1 
ATOM   1833 C C   B TYR A 1 235 ? -5.77956  -7.83675  13.59469 0.453 18.68969 ? 262 TYR A C   1 
ATOM   1834 O O   A TYR A 1 235 ? -6.51969  -8.63851  13.01407 0.547 19.78047 ? 262 TYR A O   1 
ATOM   1835 O O   B TYR A 1 235 ? -6.52005  -8.61383  12.98119 0.453 19.75633 ? 262 TYR A O   1 
ATOM   1836 C CB  A TYR A 1 235 ? -6.70608  -7.31657  15.88179 0.547 16.63141 ? 262 TYR A CB  1 
ATOM   1837 C CB  B TYR A 1 235 ? -6.69242  -7.29401  15.85051 0.453 16.63934 ? 262 TYR A CB  1 
ATOM   1838 C CG  A TYR A 1 235 ? -6.93531  -6.28340  16.98639 0.547 16.32459 ? 262 TYR A CG  1 
ATOM   1839 C CG  B TYR A 1 235 ? -6.96667  -6.25842  16.92975 0.453 16.35066 ? 262 TYR A CG  1 
ATOM   1840 C CD1 A TYR A 1 235 ? -5.85240  -5.76466  17.68947 0.547 17.27546 ? 262 TYR A CD1 1 
ATOM   1841 C CD1 B TYR A 1 235 ? -6.48834  -4.95169  16.81447 0.453 17.46075 ? 262 TYR A CD1 1 
ATOM   1842 C CD2 A TYR A 1 235 ? -8.20806  -5.82931  17.32191 0.547 19.61174 ? 262 TYR A CD2 1 
ATOM   1843 C CD2 B TYR A 1 235 ? -7.66655  -6.59843  18.06863 0.453 14.50824 ? 262 TYR A CD2 1 
ATOM   1844 C CE1 A TYR A 1 235 ? -6.02406  -4.78542  18.67658 0.547 16.17196 ? 262 TYR A CE1 1 
ATOM   1845 C CE1 B TYR A 1 235 ? -6.69617  -4.02294  17.81356 0.453 16.42676 ? 262 TYR A CE1 1 
ATOM   1846 C CE2 A TYR A 1 235 ? -8.37970  -4.87176  18.36003 0.547 21.30395 ? 262 TYR A CE2 1 
ATOM   1847 C CE2 B TYR A 1 235 ? -7.89249  -5.67389  19.06960 0.453 16.16001 ? 262 TYR A CE2 1 
ATOM   1848 C CZ  A TYR A 1 235 ? -7.26494  -4.36771  19.02297 0.547 22.29446 ? 262 TYR A CZ  1 
ATOM   1849 C CZ  B TYR A 1 235 ? -7.41091  -4.37928  18.92772 0.453 22.30234 ? 262 TYR A CZ  1 
ATOM   1850 O OH  A TYR A 1 235 ? -7.34787  -3.42722  20.04659 0.547 22.07125 ? 262 TYR A OH  1 
ATOM   1851 O OH  B TYR A 1 235 ? -7.63410  -3.43926  19.91749 0.453 23.38758 ? 262 TYR A OH  1 
ATOM   1852 N N   . PHE A 1 236 ? -4.45719  -7.95325  13.58387 1.000 13.66519 ? 263 PHE A N   1 
ATOM   1853 C CA  . PHE A 1 236 ? -3.82801  -8.95991  12.74549 1.000 14.37980 ? 263 PHE A CA  1 
ATOM   1854 C C   . PHE A 1 236 ? -2.53403  -9.41683  13.39649 1.000 19.41321 ? 263 PHE A C   1 
ATOM   1855 O O   . PHE A 1 236 ? -1.73492  -8.58798  13.83265 1.000 15.30390 ? 263 PHE A O   1 
ATOM   1856 C CB  . PHE A 1 236 ? -3.58333  -8.38196  11.33953 1.000 15.32112 ? 263 PHE A CB  1 
ATOM   1857 C CG  . PHE A 1 236 ? -2.94412  -9.37374  10.38203 1.000 15.72830 ? 263 PHE A CG  1 
ATOM   1858 C CD1 . PHE A 1 236 ? -3.66920  -10.45538 9.86953  1.000 16.14644 ? 263 PHE A CD1 1 
ATOM   1859 C CD2 . PHE A 1 236 ? -1.57086  -9.24457  10.00610 1.000 16.38650 ? 263 PHE A CD2 1 
ATOM   1860 C CE1 . PHE A 1 236 ? -3.02722  -11.37145 8.97079  1.000 17.47620 ? 263 PHE A CE1 1 
ATOM   1861 C CE2 . PHE A 1 236 ? -0.94510  -10.14930 9.13932  1.000 19.34338 ? 263 PHE A CE2 1 
ATOM   1862 C CZ  . PHE A 1 236 ? -1.69243  -11.22736 8.61123  1.000 20.39999 ? 263 PHE A CZ  1 
ATOM   1863 N N   . THR A 1 237 ? -2.31466  -10.71962 13.42852 1.000 13.67445 ? 264 THR A N   1 
ATOM   1864 C CA  . THR A 1 237 ? -1.06431  -11.25325 13.96708 1.000 12.82706 ? 264 THR A CA  1 
ATOM   1865 C C   . THR A 1 237 ? -0.67700  -12.51710 13.19699 1.000 18.96567 ? 264 THR A C   1 
ATOM   1866 O O   . THR A 1 237 ? -1.50475  -13.13493 12.52653 1.000 19.28519 ? 264 THR A O   1 
ATOM   1867 C CB  . THR A 1 237 ? -1.20443  -11.47247 15.49074 1.000 15.69253 ? 264 THR A CB  1 
ATOM   1868 O OG1 . THR A 1 237 ? 0.12002   -11.60681 16.04021 1.000 15.96232 ? 264 THR A OG1 1 
ATOM   1869 C CG2 . THR A 1 237 ? -2.11766  -12.65843 15.81509 1.000 19.77942 ? 264 THR A CG2 1 
ATOM   1870 N N   . GLN A 1 238 ? 0.58252   -12.89610 13.31514 1.000 15.16675 ? 265 GLN A N   1 
ATOM   1871 C CA  . GLN A 1 238 ? 1.18806   -13.87672 12.42157 1.000 15.94696 ? 265 GLN A CA  1 
ATOM   1872 C C   . GLN A 1 238 ? 1.92845   -14.94914 13.19767 1.000 17.66023 ? 265 GLN A C   1 
ATOM   1873 O O   . GLN A 1 238 ? 2.23517   -14.77963 14.37507 1.000 19.02121 ? 265 GLN A O   1 
ATOM   1874 C CB  . GLN A 1 238 ? 2.14496   -13.17056 11.46517 1.000 17.78369 ? 265 GLN A CB  1 
ATOM   1875 C CG  . GLN A 1 238 ? 1.39317   -12.07797 10.71356 1.000 19.67435 ? 265 GLN A CG  1 
ATOM   1876 C CD  . GLN A 1 238 ? 2.27563   -11.42540 9.68369  1.000 19.38017 ? 265 GLN A CD  1 
ATOM   1877 O OE1 . GLN A 1 238 ? 2.71825   -12.07635 8.72061  1.000 23.16361 ? 265 GLN A OE1 1 
ATOM   1878 N NE2 . GLN A 1 238 ? 2.55726   -10.13268 9.89462  1.000 18.60394 ? 265 GLN A NE2 1 
ATOM   1879 N N   . PRO A 1 239 ? 2.23777   -16.07490 12.56237 1.000 20.33472 ? 266 PRO A N   1 
ATOM   1880 C CA  . PRO A 1 239 ? 2.83834   -17.17871 13.33926 1.000 21.29497 ? 266 PRO A CA  1 
ATOM   1881 C C   . PRO A 1 239 ? 4.32219   -17.04822 13.62782 1.000 24.14518 ? 266 PRO A C   1 
ATOM   1882 O O   . PRO A 1 239 ? 4.79798   -17.75024 14.52399 1.000 28.87260 ? 266 PRO A O   1 
ATOM   1883 C CB  . PRO A 1 239 ? 2.59570   -18.42269 12.46209 1.000 25.81325 ? 266 PRO A CB  1 
ATOM   1884 C CG  . PRO A 1 239 ? 1.78583   -18.00773 11.34202 1.000 25.60158 ? 266 PRO A CG  1 
ATOM   1885 C CD  . PRO A 1 239 ? 1.66515   -16.51498 11.27562 1.000 19.54010 ? 266 PRO A CD  1 
ATOM   1886 N N   A GLN A 1 240 ? 5.04803   -16.16112 12.94458 0.525 24.35070 ? 267 GLN A N   1 
ATOM   1887 N N   B GLN A 1 240 ? 5.08057   -16.24211 12.88599 0.475 24.41851 ? 267 GLN A N   1 
ATOM   1888 C CA  A GLN A 1 240 ? 6.50404   -16.07032 13.04622 0.525 27.87449 ? 267 GLN A CA  1 
ATOM   1889 C CA  B GLN A 1 240 ? 6.52639   -16.15793 13.07753 0.475 27.81148 ? 267 GLN A CA  1 
ATOM   1890 C C   A GLN A 1 240 ? 6.89117   -14.91555 13.96727 0.525 26.29196 ? 267 GLN A C   1 
ATOM   1891 C C   B GLN A 1 240 ? 6.85955   -14.91224 13.88447 0.475 26.28026 ? 267 GLN A C   1 
ATOM   1892 O O   A GLN A 1 240 ? 6.36012   -13.80756 13.82730 0.525 23.45363 ? 267 GLN A O   1 
ATOM   1893 O O   B GLN A 1 240 ? 6.28681   -13.84204 13.65453 0.475 23.25966 ? 267 GLN A O   1 
ATOM   1894 C CB  A GLN A 1 240 ? 7.12338   -15.86595 11.65871 0.525 29.64604 ? 267 GLN A CB  1 
ATOM   1895 C CB  B GLN A 1 240 ? 7.27603   -16.11979 11.74216 0.475 29.58697 ? 267 GLN A CB  1 
ATOM   1896 C CG  A GLN A 1 240 ? 6.76369   -16.95808 10.63414 0.525 35.57312 ? 267 GLN A CG  1 
ATOM   1897 C CG  B GLN A 1 240 ? 7.00754   -17.32299 10.83331 0.475 35.42569 ? 267 GLN A CG  1 
ATOM   1898 C CD  A GLN A 1 240 ? 5.59802   -16.60887 9.70301  0.525 33.15300 ? 267 GLN A CD  1 
ATOM   1899 C CD  B GLN A 1 240 ? 7.49214   -18.62154 11.43160 0.475 35.06909 ? 267 GLN A CD  1 
ATOM   1900 O OE1 A GLN A 1 240 ? 4.84504   -15.63259 9.91184  0.525 24.44251 ? 267 GLN A OE1 1 
ATOM   1901 O OE1 B GLN A 1 240 ? 8.46579   -18.64539 12.19216 0.475 44.99708 ? 267 GLN A OE1 1 
ATOM   1902 N NE2 A GLN A 1 240 ? 5.44951   -17.41355 8.65226  0.525 41.13986 ? 267 GLN A NE2 1 
ATOM   1903 N NE2 B GLN A 1 240 ? 6.81998   -19.71928 11.09062 0.475 41.97170 ? 267 GLN A NE2 1 
ATOM   1904 N N   A GLN A 1 241 ? 7.82055   -15.16818 14.90304 0.525 26.51281 ? 268 GLN A N   1 
ATOM   1905 N N   B GLN A 1 241 ? 7.78915   -15.05487 14.83276 0.475 26.72549 ? 268 GLN A N   1 
ATOM   1906 C CA  A GLN A 1 241 ? 8.15354   -14.13181 15.88687 0.525 26.81240 ? 268 GLN A CA  1 
ATOM   1907 C CA  B GLN A 1 241 ? 8.02975   -13.95986 15.76886 0.475 27.07288 ? 268 GLN A CA  1 
ATOM   1908 C C   A GLN A 1 241 ? 8.74198   -12.88898 15.22414 0.525 30.78617 ? 268 GLN A C   1 
ATOM   1909 C C   B GLN A 1 241 ? 8.52554   -12.70938 15.05357 0.475 30.24682 ? 268 GLN A C   1 
ATOM   1910 O O   A GLN A 1 241 ? 8.61645   -11.77915 15.76824 0.525 25.58687 ? 268 GLN A O   1 
ATOM   1911 O O   B GLN A 1 241 ? 8.08384   -11.59432 15.35915 0.475 23.87086 ? 268 GLN A O   1 
ATOM   1912 C CB  A GLN A 1 241 ? 9.11663   -14.68595 16.94946 0.525 27.62806 ? 268 GLN A CB  1 
ATOM   1913 C CB  B GLN A 1 241 ? 9.02598   -14.38364 16.84414 0.475 27.22140 ? 268 GLN A CB  1 
ATOM   1914 C CG  A GLN A 1 241 ? 9.47190   -13.68723 18.09003 0.525 28.95110 ? 268 GLN A CG  1 
ATOM   1915 C CG  B GLN A 1 241 ? 9.20767   -13.30405 17.89552 0.475 29.31524 ? 268 GLN A CG  1 
ATOM   1916 C CD  A GLN A 1 241 ? 10.24624  -14.32860 19.23671 0.525 36.56424 ? 268 GLN A CD  1 
ATOM   1917 C CD  B GLN A 1 241 ? 10.61796  -13.18759 18.37650 0.475 35.76440 ? 268 GLN A CD  1 
ATOM   1918 O OE1 A GLN A 1 241 ? 11.23644  -15.03274 19.01649 0.525 34.28301 ? 268 GLN A OE1 1 
ATOM   1919 O OE1 B GLN A 1 241 ? 11.49519  -13.95764 17.97992 0.475 40.55171 ? 268 GLN A OE1 1 
ATOM   1920 N NE2 A GLN A 1 241 ? 9.79718   -14.08522 20.47573 0.525 37.62388 ? 268 GLN A NE2 1 
ATOM   1921 N NE2 B GLN A 1 241 ? 10.85692  -12.21508 19.24079 0.475 39.21880 ? 268 GLN A NE2 1 
ATOM   1922 N N   A ASN A 1 242 ? 9.35676   -13.04963 14.04317 0.525 28.07479 ? 269 ASN A N   1 
ATOM   1923 N N   B ASN A 1 242 ? 9.44528   -12.86822 14.10054 0.475 28.41450 ? 269 ASN A N   1 
ATOM   1924 C CA  A ASN A 1 242 ? 10.05143  -11.97301 13.34104 0.525 33.26351 ? 269 ASN A CA  1 
ATOM   1925 C CA  B ASN A 1 242 ? 10.02117  -11.73087 13.39295 0.475 33.16351 ? 269 ASN A CA  1 
ATOM   1926 C C   A ASN A 1 242 ? 9.33703   -11.52770 12.06870 0.525 32.10379 ? 269 ASN A C   1 
ATOM   1927 C C   B ASN A 1 242 ? 9.32265   -11.45525 12.06639 0.475 32.07988 ? 269 ASN A C   1 
ATOM   1928 O O   A ASN A 1 242 ? 9.96914   -10.92291 11.19508 0.525 34.98153 ? 269 ASN A O   1 
ATOM   1929 O O   B ASN A 1 242 ? 9.95047   -10.91961 11.14515 0.475 34.95152 ? 269 ASN A O   1 
ATOM   1930 C CB  A ASN A 1 242 ? 11.48343  -12.39655 13.00146 0.525 37.28053 ? 269 ASN A CB  1 
ATOM   1931 C CB  B ASN A 1 242 ? 11.52136  -11.93888 13.16862 0.475 37.76243 ? 269 ASN A CB  1 
ATOM   1932 C CG  A ASN A 1 242 ? 11.55498  -13.78546 12.39093 0.525 32.52971 ? 269 ASN A CG  1 
ATOM   1933 C CG  B ASN A 1 242 ? 12.30496  -12.02879 14.47440 0.475 42.00423 ? 269 ASN A CG  1 
ATOM   1934 O OD1 A ASN A 1 242 ? 10.53838  -14.37974 12.03566 0.525 32.88970 ? 269 ASN A OD1 1 
ATOM   1935 O OD1 B ASN A 1 242 ? 12.04466  -11.28881 15.42596 0.475 46.31057 ? 269 ASN A OD1 1 
ATOM   1936 N ND2 A ASN A 1 242 ? 12.76373  -14.30885 12.26863 0.525 46.49486 ? 269 ASN A ND2 1 
ATOM   1937 N ND2 B ASN A 1 242 ? 13.26354  -12.93953 14.52317 0.475 47.73444 ? 269 ASN A ND2 1 
ATOM   1938 N N   . ALA A 1 243 ? 8.04183   -11.81990 11.94328 1.000 26.62522 ? 270 ALA A N   1 
ATOM   1939 C CA  . ALA A 1 243 ? 7.28614   -11.46880 10.74510 1.000 22.43946 ? 270 ALA A CA  1 
ATOM   1940 C C   . ALA A 1 243 ? 7.21516   -9.95740  10.58647 1.000 28.02682 ? 270 ALA A C   1 
ATOM   1941 O O   . ALA A 1 243 ? 7.19762   -9.21095  11.56608 1.000 25.88157 ? 270 ALA A O   1 
ATOM   1942 C CB  . ALA A 1 243 ? 5.87006   -12.05288 10.79410 1.000 25.43080 ? 270 ALA A CB  1 
ATOM   1943 N N   . GLU A 1 244 ? 7.18448   -9.51347  9.33293  1.000 28.69270 ? 271 GLU A N   1 
ATOM   1944 C CA  . GLU A 1 244 ? 7.05143   -8.09654  9.01121  1.000 30.75606 ? 271 GLU A CA  1 
ATOM   1945 C C   . GLU A 1 244 ? 5.62477   -7.61558  9.18813  1.000 24.28707 ? 271 GLU A C   1 
ATOM   1946 O O   . GLU A 1 244 ? 4.66452   -8.37227  9.04108  1.000 24.09896 ? 271 GLU A O   1 
ATOM   1947 C CB  . GLU A 1 244 ? 7.46349   -7.82374  7.56580  1.000 35.76424 ? 271 GLU A CB  1 
ATOM   1948 C CG  . GLU A 1 244 ? 8.88212   -8.27220  7.27730  1.000 50.74758 ? 271 GLU A CG  1 
ATOM   1949 C CD  . GLU A 1 244 ? 9.33579   -7.90499  5.87890  1.000 83.46708 ? 271 GLU A CD  1 
ATOM   1950 O OE1 . GLU A 1 244 ? 8.49373   -7.40911  5.09231  1.000 75.09738 ? 271 GLU A OE1 1 
ATOM   1951 O OE2 . GLU A 1 244 ? 10.53475  -8.10889  5.57299  1.000 83.19703 ? 271 GLU A OE2 1 
ATOM   1952 N N   . SER A 1 245 ? 5.47942   -6.32351  9.47114  1.000 25.58699 ? 272 SER A N   1 
ATOM   1953 C CA  A SER A 1 245 ? 4.13222   -5.79637  9.62212  0.491 22.74776 ? 272 SER A CA  1 
ATOM   1954 C CA  B SER A 1 245 ? 4.14523   -5.75333  9.61088  0.509 22.79509 ? 272 SER A CA  1 
ATOM   1955 C C   . SER A 1 245 ? 3.38809   -5.86075  8.28854  1.000 24.56151 ? 272 SER A C   1 
ATOM   1956 O O   . SER A 1 245 ? 3.98310   -5.82340  7.20033  1.000 25.81369 ? 272 SER A O   1 
ATOM   1957 C CB  A SER A 1 245 ? 4.15749   -4.35506  10.12757 0.491 29.36556 ? 272 SER A CB  1 
ATOM   1958 C CB  B SER A 1 245 ? 4.23110   -4.28324  10.03066 0.509 29.22350 ? 272 SER A CB  1 
ATOM   1959 O OG  A SER A 1 245 ? 4.57800   -3.47259  9.11290  0.491 34.82976 ? 272 SER A OG  1 
ATOM   1960 O OG  B SER A 1 245 ? 5.03430   -4.12703  11.19094 0.509 29.33887 ? 272 SER A OG  1 
ATOM   1961 N N   . ARG A 1 246 ? 2.07816   -5.96137  8.37924  1.000 20.31511 ? 273 ARG A N   1 
ATOM   1962 C CA  . ARG A 1 246 ? 1.23411   -6.09238  7.20270  1.000 20.44828 ? 273 ARG A CA  1 
ATOM   1963 C C   . ARG A 1 246 ? 0.10878   -5.05927  7.24261  1.000 18.71369 ? 273 ARG A C   1 
ATOM   1964 O O   . ARG A 1 246 ? -1.05571  -5.42295  7.34960  1.000 18.31164 ? 273 ARG A O   1 
ATOM   1965 C CB  . ARG A 1 246 ? 0.66305   -7.51058  7.11445  1.000 18.01671 ? 273 ARG A CB  1 
ATOM   1966 C CG  . ARG A 1 246 ? 1.72774   -8.56137  6.69903  1.000 21.16800 ? 273 ARG A CG  1 
ATOM   1967 C CD  . ARG A 1 246 ? 2.19486   -8.39723  5.27871  1.000 25.82161 ? 273 ARG A CD  1 
ATOM   1968 N NE  . ARG A 1 246 ? 1.10598   -8.46554  4.30314  1.000 23.53330 ? 273 ARG A NE  1 
ATOM   1969 C CZ  . ARG A 1 246 ? 0.63991   -9.58771  3.76765  1.000 30.98708 ? 273 ARG A CZ  1 
ATOM   1970 N NH1 . ARG A 1 246 ? 1.11861   -10.77807 4.11338  1.000 29.73832 ? 273 ARG A NH1 1 
ATOM   1971 N NH2 . ARG A 1 246 ? -0.32261  -9.51335  2.85435  1.000 30.76364 ? 273 ARG A NH2 1 
ATOM   1972 N N   A ARG A 1 247 ? 0.45613   -3.77123  7.12592  0.415 20.19120 ? 274 ARG A N   1 
ATOM   1973 N N   B ARG A 1 247 ? 0.45569   -3.77162  7.12175  0.585 20.14608 ? 274 ARG A N   1 
ATOM   1974 C CA  A ARG A 1 247 ? -0.58905  -2.74739  7.12547  0.415 19.07731 ? 274 ARG A CA  1 
ATOM   1975 C CA  B ARG A 1 247 ? -0.59324  -2.75203  7.13353  0.585 19.01661 ? 274 ARG A CA  1 
ATOM   1976 C C   A ARG A 1 247 ? -1.53385  -2.91114  5.94303  0.415 20.70941 ? 274 ARG A C   1 
ATOM   1977 C C   B ARG A 1 247 ? -1.53362  -2.90500  5.94392  0.585 20.71335 ? 274 ARG A C   1 
ATOM   1978 O O   A ARG A 1 247 ? -2.70721  -2.53494  6.03109  0.415 20.65001 ? 274 ARG A O   1 
ATOM   1979 O O   B ARG A 1 247 ? -2.70624  -2.52820  6.02999  0.585 20.65764 ? 274 ARG A O   1 
ATOM   1980 C CB  A ARG A 1 247 ? 0.03891   -1.35998  7.12213  0.415 20.73688 ? 274 ARG A CB  1 
ATOM   1981 C CB  B ARG A 1 247 ? 0.04416   -1.37110  7.16644  0.585 20.69637 ? 274 ARG A CB  1 
ATOM   1982 C CG  A ARG A 1 247 ? 0.73655   -1.04729  8.43621  0.415 24.07697 ? 274 ARG A CG  1 
ATOM   1983 C CG  B ARG A 1 247 ? 0.85824   -1.17614  8.45351  0.585 23.86571 ? 274 ARG A CG  1 
ATOM   1984 C CD  A ARG A 1 247 ? 1.31610   0.35521   8.43806  0.415 29.51255 ? 274 ARG A CD  1 
ATOM   1985 C CD  B ARG A 1 247 ? 1.72233   0.08432   8.39008  0.585 30.75338 ? 274 ARG A CD  1 
ATOM   1986 N NE  A ARG A 1 247 ? 2.41242   0.50037   7.48600  0.415 33.14608 ? 274 ARG A NE  1 
ATOM   1987 N NE  B ARG A 1 247 ? 2.51134   0.29140   9.60233  0.585 36.14241 ? 274 ARG A NE  1 
ATOM   1988 C CZ  A ARG A 1 247 ? 3.23254   1.54218   7.43844  0.415 37.56415 ? 274 ARG A CZ  1 
ATOM   1989 C CZ  B ARG A 1 247 ? 3.74552   -0.16472  9.79610  0.585 48.94040 ? 274 ARG A CZ  1 
ATOM   1990 N NH1 A ARG A 1 247 ? 3.11569   2.55662   8.28418  0.415 35.85438 ? 274 ARG A NH1 1 
ATOM   1991 N NH1 B ARG A 1 247 ? 4.39147   -0.84929  8.86221  0.585 38.14136 ? 274 ARG A NH1 1 
ATOM   1992 N NH2 A ARG A 1 247 ? 4.19131   1.57159   6.51551  0.415 38.52282 ? 274 ARG A NH2 1 
ATOM   1993 N NH2 B ARG A 1 247 ? 4.34884   0.07248   10.95761 0.585 42.71992 ? 274 ARG A NH2 1 
ATOM   1994 N N   . ASP A 1 248 ? -1.04555  -3.48022  4.83280  1.000 18.96795 ? 275 ASP A N   1 
ATOM   1995 C CA  . ASP A 1 248 ? -1.91110  -3.69058  3.67263  1.000 22.31880 ? 275 ASP A CA  1 
ATOM   1996 C C   . ASP A 1 248 ? -3.10619  -4.58335  3.98792  1.000 20.01755 ? 275 ASP A C   1 
ATOM   1997 O O   . ASP A 1 248 ? -4.17074  -4.43155  3.37410  1.000 21.18607 ? 275 ASP A O   1 
ATOM   1998 C CB  . ASP A 1 248 ? -1.11534  -4.30330  2.51002  1.000 26.61369 ? 275 ASP A CB  1 
ATOM   1999 C CG  . ASP A 1 248 ? -0.56197  -5.66388  2.85313  1.000 33.22048 ? 275 ASP A CG  1 
ATOM   2000 O OD1 . ASP A 1 248 ? 0.26361   -5.74065  3.78736  1.000 24.80553 ? 275 ASP A OD1 1 
ATOM   2001 O OD2 . ASP A 1 248 ? -0.98463  -6.66287  2.24440  1.000 36.63338 ? 275 ASP A OD2 1 
ATOM   2002 N N   . VAL A 1 249 ? -2.95728  -5.52742  4.91809  1.000 19.19725 ? 276 VAL A N   1 
ATOM   2003 C CA  . VAL A 1 249 ? -4.08641  -6.37001  5.29410  1.000 15.36168 ? 276 VAL A CA  1 
ATOM   2004 C C   . VAL A 1 249 ? -5.18457  -5.54768  5.94778  1.000 17.18698 ? 276 VAL A C   1 
ATOM   2005 O O   . VAL A 1 249 ? -6.37444  -5.79142  5.71311  1.000 20.02761 ? 276 VAL A O   1 
ATOM   2006 C CB  . VAL A 1 249 ? -3.60222  -7.51777  6.19667  1.000 18.91532 ? 276 VAL A CB  1 
ATOM   2007 C CG1 . VAL A 1 249 ? -4.81975  -8.23891  6.85036  1.000 21.82632 ? 276 VAL A CG1 1 
ATOM   2008 C CG2 . VAL A 1 249 ? -2.67683  -8.45937  5.38885  1.000 20.61487 ? 276 VAL A CG2 1 
ATOM   2009 N N   . LEU A 1 250 ? -4.81142  -4.58067  6.78872  1.000 16.16253 ? 277 LEU A N   1 
ATOM   2010 C CA  . LEU A 1 250 ? -5.80974  -3.73988  7.45704  1.000 17.66131 ? 277 LEU A CA  1 
ATOM   2011 C C   . LEU A 1 250 ? -6.52110  -2.85844  6.44310  1.000 20.79791 ? 277 LEU A C   1 
ATOM   2012 O O   . LEU A 1 250 ? -7.74468  -2.68463  6.49788  1.000 17.84150 ? 277 LEU A O   1 
ATOM   2013 C CB  . LEU A 1 250 ? -5.15105  -2.89208  8.54993  1.000 18.40678 ? 277 LEU A CB  1 
ATOM   2014 C CG  . LEU A 1 250 ? -4.21133  -3.58720  9.52574  1.000 17.20771 ? 277 LEU A CG  1 
ATOM   2015 C CD1 . LEU A 1 250 ? -3.86082  -2.67826  10.63806 1.000 16.36104 ? 277 LEU A CD1 1 
ATOM   2016 C CD2 . LEU A 1 250 ? -4.88666  -4.85644  10.03018 1.000 17.08824 ? 277 LEU A CD2 1 
ATOM   2017 N N   . ALA A 1 251 ? -5.75977  -2.29969  5.49731  1.000 19.81502 ? 278 ALA A N   1 
ATOM   2018 C CA  . ALA A 1 251 ? -6.34738  -1.52558  4.41506  1.000 21.35422 ? 278 ALA A CA  1 
ATOM   2019 C C   . ALA A 1 251 ? -7.33755  -2.36917  3.61499  1.000 21.99326 ? 278 ALA A C   1 
ATOM   2020 O O   . ALA A 1 251 ? -8.41979  -1.90041  3.24152  1.000 21.78389 ? 278 ALA A O   1 
ATOM   2021 C CB  . ALA A 1 251 ? -5.21759  -0.99211  3.52535  1.000 20.12710 ? 278 ALA A CB  1 
ATOM   2022 N N   . SER A 1 252 ? -6.97753  -3.62031  3.33415  1.000 19.70414 ? 279 SER A N   1 
ATOM   2023 C CA  . SER A 1 252 ? -7.83369  -4.45212  2.50735  1.000 18.79611 ? 279 SER A CA  1 
ATOM   2024 C C   . SER A 1 252 ? -9.08432  -4.85610  3.25838  1.000 21.65237 ? 279 SER A C   1 
ATOM   2025 O O   . SER A 1 252 ? -10.16476 -4.98809  2.67388  1.000 23.21434 ? 279 SER A O   1 
ATOM   2026 C CB  . SER A 1 252 ? -7.07409  -5.69183  2.09014  1.000 22.56004 ? 279 SER A CB  1 
ATOM   2027 O OG  . SER A 1 252 ? -6.19584  -5.37314  1.03705  1.000 26.98276 ? 279 SER A OG  1 
ATOM   2028 N N   . ALA A 1 253 ? -8.94925  -5.09923  4.54433  1.000 20.16244 ? 280 ALA A N   1 
ATOM   2029 C CA  . ALA A 1 253 ? -10.12542 -5.43442  5.32740  1.000 18.22704 ? 280 ALA A CA  1 
ATOM   2030 C C   . ALA A 1 253 ? -11.08661 -4.25754  5.38140  1.000 21.07620 ? 280 ALA A C   1 
ATOM   2031 O O   . ALA A 1 253 ? -12.30316 -4.43385  5.24744  1.000 23.34992 ? 280 ALA A O   1 
ATOM   2032 C CB  . ALA A 1 253 ? -9.71780  -5.87136  6.73973  1.000 21.15862 ? 280 ALA A CB  1 
ATOM   2033 N N   . ALA A 1 254 ? -10.55584 -3.04108  5.55777  1.000 21.17613 ? 281 ALA A N   1 
ATOM   2034 C CA  . ALA A 1 254 ? -11.40332 -1.85341  5.52052  1.000 26.05912 ? 281 ALA A CA  1 
ATOM   2035 C C   . ALA A 1 254 ? -12.12541 -1.73217  4.17925  1.000 28.35545 ? 281 ALA A C   1 
ATOM   2036 O O   . ALA A 1 254 ? -13.31996 -1.41111  4.13599  1.000 27.01468 ? 281 ALA A O   1 
ATOM   2037 C CB  . ALA A 1 254 ? -10.56369 -0.60851  5.76237  1.000 24.87927 ? 281 ALA A CB  1 
ATOM   2038 N N   . ARG A 1 255 ? -11.40922 -1.98442  3.07605  1.000 25.59235 ? 282 ARG A N   1 
ATOM   2039 C CA  A ARG A 1 255 ? -12.00506 -1.86534  1.74888  0.483 24.56378 ? 282 ARG A CA  1 
ATOM   2040 C CA  B ARG A 1 255 ? -12.01810 -1.85214  1.75459  0.517 24.53220 ? 282 ARG A CA  1 
ATOM   2041 C C   . ARG A 1 255 ? -13.15710 -2.84309  1.58051  1.000 25.06403 ? 282 ARG A C   1 
ATOM   2042 O O   . ARG A 1 255 ? -14.19466 -2.49953  1.00445  1.000 29.67312 ? 282 ARG A O   1 
ATOM   2043 C CB  A ARG A 1 255 ? -10.93276 -2.11131  0.69085  0.483 23.99869 ? 282 ARG A CB  1 
ATOM   2044 C CB  B ARG A 1 255 ? -10.97196 -2.04693  0.65392  0.517 23.94907 ? 282 ARG A CB  1 
ATOM   2045 C CG  A ARG A 1 255 ? -11.34615 -1.84999  -0.72617 0.483 32.60010 ? 282 ARG A CG  1 
ATOM   2046 C CG  B ARG A 1 255 ? -11.51905 -1.86853  -0.75243 0.517 32.62370 ? 282 ARG A CG  1 
ATOM   2047 C CD  A ARG A 1 255 ? -10.17693 -2.11034  -1.66428 0.483 31.72891 ? 282 ARG A CD  1 
ATOM   2048 C CD  B ARG A 1 255 ? -10.43997 -2.01432  -1.82656 0.517 31.93668 ? 282 ARG A CD  1 
ATOM   2049 N NE  A ARG A 1 255 ? -8.99816  -1.31483  -1.34029 0.483 34.86541 ? 282 ARG A NE  1 
ATOM   2050 N NE  B ARG A 1 255 ? -9.50248  -0.89732  -1.86306 0.517 37.44354 ? 282 ARG A NE  1 
ATOM   2051 C CZ  A ARG A 1 255 ? -7.88131  -1.78804  -0.79684 0.483 39.68336 ? 282 ARG A CZ  1 
ATOM   2052 C CZ  B ARG A 1 255 ? -8.27893  -0.93141  -1.35022 0.517 42.00753 ? 282 ARG A CZ  1 
ATOM   2053 N NH1 A ARG A 1 255 ? -7.73807  -3.07403  -0.51238 0.483 29.19383 ? 282 ARG A NH1 1 
ATOM   2054 N NH1 B ARG A 1 255 ? -7.79560  -2.02849  -0.78586 0.517 39.82583 ? 282 ARG A NH1 1 
ATOM   2055 N NH2 A ARG A 1 255 ? -6.87961  -0.94880  -0.53575 0.483 37.43800 ? 282 ARG A NH2 1 
ATOM   2056 N NH2 B ARG A 1 255 ? -7.51977  0.16138   -1.40554 0.517 45.47237 ? 282 ARG A NH2 1 
ATOM   2057 N N   . ILE A 1 256 ? -12.98712 -4.07085  2.10664  1.000 25.95160 ? 283 ILE A N   1 
ATOM   2058 C CA  . ILE A 1 256 ? -14.03186 -5.09151  2.01483  1.000 25.73913 ? 283 ILE A CA  1 
ATOM   2059 C C   . ILE A 1 256 ? -15.26244 -4.67343  2.80482  1.000 29.89785 ? 283 ILE A C   1 
ATOM   2060 O O   . ILE A 1 256 ? -16.40089 -4.87515  2.36514  1.000 32.85284 ? 283 ILE A O   1 
ATOM   2061 C CB  . ILE A 1 256 ? -13.47468 -6.43383  2.51868  1.000 26.41843 ? 283 ILE A CB  1 
ATOM   2062 C CG1 . ILE A 1 256 ? -12.60061 -7.05478  1.44196  1.000 27.33550 ? 283 ILE A CG1 1 
ATOM   2063 C CG2 . ILE A 1 256 ? -14.60517 -7.39872  2.88857  1.000 29.64978 ? 283 ILE A CG2 1 
ATOM   2064 C CD1 . ILE A 1 256 ? -11.60492 -8.07604  2.00446  1.000 26.39852 ? 283 ILE A CD1 1 
ATOM   2065 N N   . ILE A 1 257 ? -15.04697 -4.12863  4.00339  1.000 28.85883 ? 284 ILE A N   1 
ATOM   2066 C CA  . ILE A 1 257 ? -16.14501 -3.61037  4.82498  1.000 28.93314 ? 284 ILE A CA  1 
ATOM   2067 C C   . ILE A 1 257 ? -16.83691 -2.44292  4.13948  1.000 35.68561 ? 284 ILE A C   1 
ATOM   2068 O O   . ILE A 1 257 ? -18.07488 -2.35953  4.10953  1.000 41.70788 ? 284 ILE A O   1 
ATOM   2069 C CB  . ILE A 1 257 ? -15.60868 -3.20308  6.21309  1.000 30.88348 ? 284 ILE A CB  1 
ATOM   2070 C CG1 . ILE A 1 257 ? -15.09754 -4.42836  6.95894  1.000 32.52139 ? 284 ILE A CG1 1 
ATOM   2071 C CG2 . ILE A 1 257 ? -16.67997 -2.45611  6.99430  1.000 39.79631 ? 284 ILE A CG2 1 
ATOM   2072 C CD1 . ILE A 1 257 ? -16.18160 -5.34719  7.43234  1.000 45.62920 ? 284 ILE A CD1 1 
ATOM   2073 N N   . ALA A 1 258 ? -16.05192 -1.51081  3.58685  1.000 31.97022 ? 285 ALA A N   1 
ATOM   2074 C CA  . ALA A 1 258 ? -16.63749 -0.33226  2.95085  1.000 33.76668 ? 285 ALA A CA  1 
ATOM   2075 C C   . ALA A 1 258 ? -17.49212 -0.68905  1.73032  1.000 41.38689 ? 285 ALA A C   1 
ATOM   2076 O O   . ALA A 1 258 ? -18.40947 0.06516   1.37389  1.000 45.04046 ? 285 ALA A O   1 
ATOM   2077 C CB  . ALA A 1 258 ? -15.53204 0.65144   2.55924  1.000 35.83318 ? 285 ALA A CB  1 
ATOM   2078 N N   . GLU A 1 259 ? -17.20030 -1.81904  1.07373  1.000 37.59988 ? 286 GLU A N   1 
ATOM   2079 C CA  . GLU A 1 259 ? -18.03422 -2.29072  -0.02275 1.000 47.72741 ? 286 GLU A CA  1 
ATOM   2080 C C   . GLU A 1 259 ? -19.46200 -2.57717  0.43413  1.000 58.90078 ? 286 GLU A C   1 
ATOM   2081 O O   . GLU A 1 259 ? -20.39356 -2.48232  -0.37084 1.000 70.34804 ? 286 GLU A O   1 
ATOM   2082 C CB  . GLU A 1 259 ? -17.40586 -3.53910  -0.64581 1.000 45.18945 ? 286 GLU A CB  1 
ATOM   2083 C CG  . GLU A 1 259 ? -16.11841 -3.28022  -1.39794 1.000 56.99301 ? 286 GLU A CG  1 
ATOM   2084 C CD  . GLU A 1 259 ? -15.44430 -4.57292  -1.85375 1.000 74.48849 ? 286 GLU A CD  1 
ATOM   2085 O OE1 . GLU A 1 259 ? -16.07895 -5.65080  -1.74524 1.000 69.18949 ? 286 GLU A OE1 1 
ATOM   2086 O OE2 . GLU A 1 259 ? -14.27821 -4.50917  -2.31089 1.000 69.65076 ? 286 GLU A OE2 1 
ATOM   2087 N N   . GLY A 1 260 ? -19.65986 -2.92542  1.70820  1.000 62.48737 ? 287 GLY A N   1 
ATOM   2088 C CA  . GLY A 1 260 ? -21.00229 -3.06019  2.27642  1.000 58.31279 ? 287 GLY A CA  1 
ATOM   2089 C C   . GLY A 1 260 ? -21.80410 -1.76699  2.44832  1.000 73.15621 ? 287 GLY A C   1 
ATOM   2090 O O   . GLY A 1 260 ? -22.45794 -1.27765  1.51705  1.000 79.89963 ? 287 GLY A O   1 
HETATM 2091 S S   . SO4 B 2 .   ? 2.44489   2.04044   16.04771 0.889 29.91899 ? 301 SO4 A S   1 
HETATM 2092 O O1  . SO4 B 2 .   ? 3.27830   3.03908   15.39299 0.889 47.22914 ? 301 SO4 A O1  1 
HETATM 2093 O O2  . SO4 B 2 .   ? 2.18144   0.95245   15.13168 0.889 34.98439 ? 301 SO4 A O2  1 
HETATM 2094 O O3  . SO4 B 2 .   ? 2.99185   1.64458   17.32288 0.889 29.74622 ? 301 SO4 A O3  1 
HETATM 2095 O O4  . SO4 B 2 .   ? 1.14629   2.64003   16.34361 0.889 37.93807 ? 301 SO4 A O4  1 
HETATM 2096 O O   . HOH C 3 .   ? 5.56361   21.49778  30.91774 1.000 44.51251 ? 401 HOH A O   1 
HETATM 2097 O O   . HOH C 3 .   ? 0.73034   0.94234   24.46145 0.353 14.14644 ? 402 HOH A O   1 
HETATM 2098 O O   . HOH C 3 .   ? 4.78547   4.77463   14.71582 1.000 54.25977 ? 403 HOH A O   1 
HETATM 2099 O O   . HOH C 3 .   ? 8.26294   12.05808  35.88080 1.000 49.30188 ? 404 HOH A O   1 
HETATM 2100 O O   . HOH C 3 .   ? -22.74095 6.71567   25.87301 1.000 46.31453 ? 405 HOH A O   1 
HETATM 2101 O O   . HOH C 3 .   ? 1.51093   12.33632  36.55505 1.000 40.85503 ? 406 HOH A O   1 
HETATM 2102 O O   . HOH C 3 .   ? -18.16014 7.12114   32.30544 1.000 41.24576 ? 407 HOH A O   1 
HETATM 2103 O O   . HOH C 3 .   ? -14.389   16.923    15.526   1.000 46.16142 ? 408 HOH A O   1 
HETATM 2104 O O   . HOH C 3 .   ? 7.17932   19.05202  21.12812 1.000 38.96281 ? 409 HOH A O   1 
HETATM 2105 O O   . HOH C 3 .   ? 8.32680   -0.06952  32.86047 1.000 45.42719 ? 410 HOH A O   1 
HETATM 2106 O O   . HOH C 3 .   ? 1.24497   -15.31074 30.07284 1.000 35.92938 ? 411 HOH A O   1 
HETATM 2107 O O   . HOH C 3 .   ? 5.51233   8.02700   15.22343 1.000 39.32820 ? 412 HOH A O   1 
HETATM 2108 O O   . HOH C 3 .   ? 2.80502   -0.30940  22.19627 1.000 24.86494 ? 413 HOH A O   1 
HETATM 2109 O O   . HOH C 3 .   ? 7.91374   -11.51126 21.27308 1.000 28.11063 ? 414 HOH A O   1 
HETATM 2110 O O   . HOH C 3 .   ? 2.59198   -0.51475  18.73070 1.000 31.78976 ? 415 HOH A O   1 
HETATM 2111 O O   . HOH C 3 .   ? 5.72212   -2.31438  19.34593 1.000 41.83673 ? 416 HOH A O   1 
HETATM 2112 O O   . HOH C 3 .   ? -11.33719 -3.53902  24.78484 1.000 18.47706 ? 417 HOH A O   1 
HETATM 2113 O O   . HOH C 3 .   ? 9.26154   5.00027   30.67521 1.000 27.66096 ? 418 HOH A O   1 
HETATM 2114 O O   . HOH C 3 .   ? 14.21902  16.06073  39.09857 1.000 46.11951 ? 419 HOH A O   1 
HETATM 2115 O O   . HOH C 3 .   ? 13.16232  17.65379  15.94829 1.000 39.79187 ? 420 HOH A O   1 
HETATM 2116 O O   . HOH C 3 .   ? -12.63777 2.30336   -0.35095 1.000 41.51977 ? 421 HOH A O   1 
HETATM 2117 O O   . HOH C 3 .   ? -0.92180  21.56734  28.13356 1.000 46.99779 ? 422 HOH A O   1 
HETATM 2118 O O   . HOH C 3 .   ? -17.52578 -0.97916  26.61788 1.000 45.00032 ? 423 HOH A O   1 
HETATM 2119 O O   . HOH C 3 .   ? -17.06620 18.21395  29.61418 1.000 50.33845 ? 424 HOH A O   1 
HETATM 2120 O O   . HOH C 3 .   ? -4.15139  13.01532  10.62872 1.000 44.83428 ? 425 HOH A O   1 
HETATM 2121 O O   . HOH C 3 .   ? 17.33670  6.17900   28.29941 1.000 54.26985 ? 426 HOH A O   1 
HETATM 2122 O O   . HOH C 3 .   ? 2.78911   -19.84643 22.77289 1.000 31.68269 ? 427 HOH A O   1 
HETATM 2123 O O   . HOH C 3 .   ? -18.28423 12.69111  19.22862 1.000 43.89669 ? 428 HOH A O   1 
HETATM 2124 O O   . HOH C 3 .   ? 10.19481  -8.00362  22.21487 1.000 48.20785 ? 429 HOH A O   1 
HETATM 2125 O O   . HOH C 3 .   ? 7.51035   -8.98042  14.20580 1.000 28.43392 ? 430 HOH A O   1 
HETATM 2126 O O   . HOH C 3 .   ? -1.11832  -0.08735  2.96330  1.000 27.58389 ? 431 HOH A O   1 
HETATM 2127 O O   . HOH C 3 .   ? 1.63200   -8.51490  23.79219 1.000 25.47911 ? 432 HOH A O   1 
HETATM 2128 O O   . HOH C 3 .   ? 1.07102   7.59706   8.50511  1.000 30.62281 ? 433 HOH A O   1 
HETATM 2129 O O   . HOH C 3 .   ? -0.65166  6.58131   16.50428 1.000 24.47702 ? 434 HOH A O   1 
HETATM 2130 O O   . HOH C 3 .   ? 5.43608   21.82702  27.98205 1.000 39.55937 ? 435 HOH A O   1 
HETATM 2131 O O   . HOH C 3 .   ? 4.71757   -5.77327  13.30008 1.000 32.75104 ? 436 HOH A O   1 
HETATM 2132 O O   . HOH C 3 .   ? -9.34765  -17.82788 6.71265  1.000 31.67370 ? 437 HOH A O   1 
HETATM 2133 O O   . HOH C 3 .   ? -1.35568  -0.36782  11.57184 1.000 19.76897 ? 438 HOH A O   1 
HETATM 2134 O O   . HOH C 3 .   ? -7.56594  -3.12146  38.08732 1.000 31.17714 ? 439 HOH A O   1 
HETATM 2135 O O   . HOH C 3 .   ? -7.27933  16.96569  14.88930 1.000 41.14067 ? 440 HOH A O   1 
HETATM 2136 O O   . HOH C 3 .   ? -10.27975 17.89576  30.39787 1.000 47.72603 ? 441 HOH A O   1 
HETATM 2137 O O   . HOH C 3 .   ? -15.57834 -10.45890 23.13737 1.000 32.20034 ? 442 HOH A O   1 
HETATM 2138 O O   . HOH C 3 .   ? -0.40046  -5.84886  23.61015 1.000 17.66455 ? 443 HOH A O   1 
HETATM 2139 O O   . HOH C 3 .   ? 7.99759   -2.96686  29.98035 1.000 23.15656 ? 444 HOH A O   1 
HETATM 2140 O O   . HOH C 3 .   ? 2.52146   -4.22113  3.85144  1.000 41.80981 ? 445 HOH A O   1 
HETATM 2141 O O   . HOH C 3 .   ? 2.65772   -11.57943 25.02392 1.000 17.03645 ? 446 HOH A O   1 
HETATM 2142 O O   . HOH C 3 .   ? 0.11117   -10.57991 24.51229 1.000 21.34420 ? 447 HOH A O   1 
HETATM 2143 O O   . HOH C 3 .   ? 9.23686   -6.96185  16.10337 1.000 57.25803 ? 448 HOH A O   1 
HETATM 2144 O O   . HOH C 3 .   ? 12.735    20.465    21.653   1.000 30.47883 ? 449 HOH A O   1 
HETATM 2145 O O   . HOH C 3 .   ? -13.68640 -17.06834 16.19638 1.000 37.83263 ? 450 HOH A O   1 
HETATM 2146 O O   . HOH C 3 .   ? -5.80545  4.42463   9.43331  1.000 23.73041 ? 451 HOH A O   1 
HETATM 2147 O O   . HOH C 3 .   ? -2.71882  8.91793   10.12717 1.000 30.92250 ? 452 HOH A O   1 
HETATM 2148 O O   . HOH C 3 .   ? -0.91110  -12.64374 22.97359 1.000 21.53385 ? 453 HOH A O   1 
HETATM 2149 O O   . HOH C 3 .   ? -13.88386 -17.43855 1.71629  1.000 33.33226 ? 454 HOH A O   1 
HETATM 2150 O O   . HOH C 3 .   ? 0.42980   -13.36227 18.32510 1.000 19.25459 ? 455 HOH A O   1 
HETATM 2151 O O   . HOH C 3 .   ? -4.20115  8.16103   39.95859 1.000 43.17452 ? 456 HOH A O   1 
HETATM 2152 O O   . HOH C 3 .   ? 4.77852   3.46791   33.89342 1.000 30.55745 ? 457 HOH A O   1 
HETATM 2153 O O   . HOH C 3 .   ? 1.41540   -14.37453 7.88881  1.000 37.54897 ? 458 HOH A O   1 
HETATM 2154 O O   . HOH C 3 .   ? -1.09278  15.83083  14.28809 1.000 52.64787 ? 459 HOH A O   1 
HETATM 2155 O O   . HOH C 3 .   ? -4.18459  -17.80583 7.67021  1.000 30.92845 ? 460 HOH A O   1 
HETATM 2156 O O   . HOH C 3 .   ? -8.23287  4.77969   36.26642 1.000 38.97666 ? 461 HOH A O   1 
HETATM 2157 O O   . HOH C 3 .   ? -4.61327  8.46526   17.67235 1.000 30.75910 ? 462 HOH A O   1 
HETATM 2158 O O   . HOH C 3 .   ? -0.35464  3.12203   8.80468  1.000 26.88967 ? 463 HOH A O   1 
HETATM 2159 O O   . HOH C 3 .   ? 10.367    -16.860   20.939   1.000 45.50119 ? 464 HOH A O   1 
HETATM 2160 O O   . HOH C 3 .   ? 2.16231   5.25155   39.81136 1.000 35.41484 ? 465 HOH A O   1 
HETATM 2161 O O   . HOH C 3 .   ? 10.02899  -0.04730  30.75124 1.000 36.34731 ? 466 HOH A O   1 
HETATM 2162 O O   . HOH C 3 .   ? 3.32701   -19.48948 16.14368 1.000 32.60707 ? 467 HOH A O   1 
HETATM 2163 O O   . HOH C 3 .   ? -13.12733 -0.37457  37.99660 1.000 34.23677 ? 468 HOH A O   1 
HETATM 2164 O O   . HOH C 3 .   ? 0.163     -6.115    36.110   1.000 33.89906 ? 469 HOH A O   1 
HETATM 2165 O O   . HOH C 3 .   ? -13.85960 -9.34454  33.54152 1.000 49.73195 ? 470 HOH A O   1 
HETATM 2166 O O   . HOH C 3 .   ? 7.38830   -6.91541  31.75018 1.000 38.93295 ? 471 HOH A O   1 
HETATM 2167 O O   . HOH C 3 .   ? -13.54495 12.00486  37.48231 1.000 37.97981 ? 472 HOH A O   1 
HETATM 2168 O O   . HOH C 3 .   ? 3.19117   -11.79329 5.95968  1.000 37.13742 ? 473 HOH A O   1 
HETATM 2169 O O   . HOH C 3 .   ? 8.53688   -5.52213  22.95343 1.000 48.54957 ? 474 HOH A O   1 
HETATM 2170 O O   . HOH C 3 .   ? 1.32082   0.23332   12.54713 1.000 35.43550 ? 475 HOH A O   1 
HETATM 2171 O O   . HOH C 3 .   ? -6.28486  5.17406   38.65595 1.000 35.91574 ? 476 HOH A O   1 
HETATM 2172 O O   . HOH C 3 .   ? 2.68472   16.53624  22.26651 1.000 34.56875 ? 477 HOH A O   1 
HETATM 2173 O O   . HOH C 3 .   ? -2.72082  -10.96554 1.28592  1.000 30.69183 ? 478 HOH A O   1 
HETATM 2174 O O   . HOH C 3 .   ? -4.87568  -7.88264  34.20950 1.000 33.57058 ? 479 HOH A O   1 
HETATM 2175 O O   . HOH C 3 .   ? -4.70564  -3.02123  0.50004  1.000 33.96575 ? 480 HOH A O   1 
HETATM 2176 O O   . HOH C 3 .   ? 12.88114  7.24945   19.69805 1.000 38.59273 ? 481 HOH A O   1 
HETATM 2177 O O   . HOH C 3 .   ? 7.55163   -0.98841  20.78135 1.000 44.85502 ? 482 HOH A O   1 
HETATM 2178 O O   . HOH C 3 .   ? -2.91839  -5.14922  35.60555 1.000 31.50751 ? 483 HOH A O   1 
HETATM 2179 O O   . HOH C 3 .   ? -4.63823  17.40362  17.41358 1.000 51.49942 ? 484 HOH A O   1 
HETATM 2180 O O   . HOH C 3 .   ? -3.34680  -8.30501  17.13227 0.372 13.70216 ? 485 HOH A O   1 
HETATM 2181 O O   . HOH C 3 .   ? -17.58625 -6.71856  0.51950  1.000 46.78684 ? 486 HOH A O   1 
HETATM 2182 O O   . HOH C 3 .   ? -7.53051  -17.45204 19.14869 1.000 34.62281 ? 487 HOH A O   1 
HETATM 2183 O O   . HOH C 3 .   ? 5.06564   2.77462   19.21975 1.000 33.09582 ? 488 HOH A O   1 
HETATM 2184 O O   . HOH C 3 .   ? 0.38641   -15.45800 16.46300 1.000 25.82390 ? 489 HOH A O   1 
HETATM 2185 O O   . HOH C 3 .   ? -15.33622 -15.57066 12.72624 1.000 35.52846 ? 490 HOH A O   1 
HETATM 2186 O O   . HOH C 3 .   ? 3.36699   10.56808  35.05530 1.000 25.86742 ? 491 HOH A O   1 
HETATM 2187 O O   . HOH C 3 .   ? -21.08016 -10.60917 12.04074 1.000 45.12968 ? 492 HOH A O   1 
HETATM 2188 O O   . HOH C 3 .   ? -18.89006 -0.77173  35.46195 1.000 55.44057 ? 493 HOH A O   1 
HETATM 2189 O O   . HOH C 3 .   ? -1.90331  -14.26713 19.22403 1.000 30.37138 ? 494 HOH A O   1 
HETATM 2190 O O   . HOH C 3 .   ? -17.53605 9.87822   25.67659 1.000 27.37797 ? 495 HOH A O   1 
HETATM 2191 O O   . HOH C 3 .   ? -21.13250 13.44706  28.03030 1.000 53.13363 ? 496 HOH A O   1 
HETATM 2192 O O   . HOH C 3 .   ? -2.30039  -16.15487 16.19787 1.000 36.67770 ? 497 HOH A O   1 
HETATM 2193 O O   . HOH C 3 .   ? -14.54978 19.21269  40.28255 1.000 48.07629 ? 498 HOH A O   1 
HETATM 2194 O O   . HOH C 3 .   ? -12.43548 -12.83776 29.28866 1.000 58.66807 ? 499 HOH A O   1 
HETATM 2195 O O   . HOH C 3 .   ? 1.34099   -18.91257 7.70396  1.000 47.04637 ? 500 HOH A O   1 
HETATM 2196 O O   . HOH C 3 .   ? -8.59330  13.00256  10.07388 1.000 39.97267 ? 501 HOH A O   1 
HETATM 2197 O O   . HOH C 3 .   ? -14.21936 -14.03631 24.41579 1.000 42.06695 ? 502 HOH A O   1 
HETATM 2198 O O   . HOH C 3 .   ? 3.15337   -2.82357  6.45532  1.000 31.09850 ? 503 HOH A O   1 
HETATM 2199 O O   . HOH C 3 .   ? 2.01723   2.73768   11.41256 1.000 43.45140 ? 504 HOH A O   1 
HETATM 2200 O O   . HOH C 3 .   ? 7.48879   -11.49191 7.15520  1.000 40.95800 ? 505 HOH A O   1 
HETATM 2201 O O   . HOH C 3 .   ? -16.93904 -13.58446 15.10753 1.000 33.15724 ? 506 HOH A O   1 
HETATM 2202 O O   . HOH C 3 .   ? 7.60024   14.76732  37.31593 1.000 47.73741 ? 507 HOH A O   1 
HETATM 2203 O O   . HOH C 3 .   ? 5.78887   -4.09706  32.83499 1.000 29.05961 ? 508 HOH A O   1 
HETATM 2204 O O   . HOH C 3 .   ? 4.75551   9.47067   12.87711 1.000 39.69510 ? 509 HOH A O   1 
HETATM 2205 O O   . HOH C 3 .   ? -4.25561  -14.65699 23.86556 1.000 37.64606 ? 510 HOH A O   1 
HETATM 2206 O O   . HOH C 3 .   ? 8.88320   6.54410   32.91325 1.000 45.93006 ? 511 HOH A O   1 
HETATM 2207 O O   . HOH C 3 .   ? 0.074     -11.029   0.315    1.000 26.94161 ? 512 HOH A O   1 
HETATM 2208 O O   . HOH C 3 .   ? 0.635     -12.947   2.105    1.000 30.55349 ? 513 HOH A O   1 
HETATM 2209 O O   . HOH C 3 .   ? 7.69958   -5.08058  19.26895 1.000 50.24520 ? 514 HOH A O   1 
HETATM 2210 O O   . HOH C 3 .   ? 2.81506   -16.44908 7.51553  1.000 45.12305 ? 515 HOH A O   1 
HETATM 2211 O O   . HOH C 3 .   ? -9.74461  7.20886   35.46750 1.000 29.03274 ? 516 HOH A O   1 
HETATM 2212 O O   . HOH C 3 .   ? -16.42748 -6.25508  27.39882 1.000 38.90859 ? 517 HOH A O   1 
HETATM 2213 O O   . HOH C 3 .   ? -14.99241 -15.30649 17.64427 1.000 31.00880 ? 518 HOH A O   1 
HETATM 2214 O O   . HOH C 3 .   ? -16.58876 -3.64796  25.66193 1.000 32.98072 ? 519 HOH A O   1 
HETATM 2215 O O   . HOH C 3 .   ? -12.11945 20.01944  24.23136 1.000 40.85570 ? 520 HOH A O   1 
HETATM 2216 O O   . HOH C 3 .   ? 3.59456   -10.09481 33.48286 1.000 35.89104 ? 521 HOH A O   1 
HETATM 2217 O O   . HOH C 3 .   ? 10.83697  20.86646  27.38196 1.000 45.91660 ? 522 HOH A O   1 
HETATM 2218 O O   . HOH C 3 .   ? -1.22149  -16.12182 13.27614 1.000 31.96395 ? 523 HOH A O   1 
HETATM 2219 O O   . HOH C 3 .   ? -5.34888  -15.63361 21.43344 1.000 47.79093 ? 524 HOH A O   1 
HETATM 2220 O O   . HOH C 3 .   ? 0.31904   12.64866  40.01464 1.000 58.29442 ? 525 HOH A O   1 
HETATM 2221 O O   . HOH C 3 .   ? 6.33194   -19.33811 18.56353 1.000 35.82069 ? 526 HOH A O   1 
HETATM 2222 O O   . HOH C 3 .   ? 8.75352   -18.04054 15.77256 1.000 33.72495 ? 527 HOH A O   1 
HETATM 2223 O O   . HOH C 3 .   ? 7.53322   -9.54909  29.67256 1.000 34.65458 ? 528 HOH A O   1 
HETATM 2224 O O   . HOH C 3 .   ? 17.48290  9.98340   34.60363 1.000 40.05533 ? 529 HOH A O   1 
HETATM 2225 O O   . HOH C 3 .   ? 14.03968  4.98217   18.36659 1.000 51.18030 ? 530 HOH A O   1 
HETATM 2226 O O   . HOH C 3 .   ? 0.01166   -10.50446 34.30000 1.000 49.58588 ? 531 HOH A O   1 
HETATM 2227 O O   . HOH C 3 .   ? 5.38010   0.21846   20.47086 1.000 33.15994 ? 532 HOH A O   1 
HETATM 2228 O O   . HOH C 3 .   ? -5.97073  -17.97298 11.22411 1.000 38.22616 ? 533 HOH A O   1 
HETATM 2229 O O   . HOH C 3 .   ? 9.54288   -12.45480 23.33201 1.000 54.14222 ? 534 HOH A O   1 
HETATM 2230 O O   . HOH C 3 .   ? -9.05921  12.46515  7.85642  1.000 50.71375 ? 535 HOH A O   1 
HETATM 2231 O O   . HOH C 3 .   ? -12.25675 -13.67808 26.21924 1.000 56.68037 ? 536 HOH A O   1 
HETATM 2232 O O   . HOH C 3 .   ? -19.44233 -11.06415 23.94344 1.000 62.27602 ? 537 HOH A O   1 
HETATM 2233 O O   . HOH C 3 .   ? -11.40415 -18.40630 1.76249  1.000 48.19989 ? 538 HOH A O   1 
HETATM 2234 O O   . HOH C 3 .   ? 3.38069   11.13711  8.44132  1.000 63.28436 ? 539 HOH A O   1 
HETATM 2235 O O   . HOH C 3 .   ? 8.49326   -3.39476  21.25927 1.000 55.99801 ? 540 HOH A O   1 
HETATM 2236 O O   . HOH C 3 .   ? -3.17917  -13.27605 21.41520 1.000 35.07972 ? 541 HOH A O   1 
HETATM 2237 O O   . HOH C 3 .   ? -10.66794 18.11445  27.92790 1.000 47.64636 ? 542 HOH A O   1 
HETATM 2238 O O   . HOH C 3 .   ? 5.60364   10.42042  36.38624 1.000 45.14867 ? 543 HOH A O   1 
HETATM 2239 O O   . HOH C 3 .   ? -17.301   15.525    20.234   1.000 38.27144 ? 544 HOH A O   1 
HETATM 2240 O O   . HOH C 3 .   ? 2.767     1.069     39.471   1.000 51.36246 ? 545 HOH A O   1 
HETATM 2241 O O   . HOH C 3 .   ? 2.53466   15.43469  19.91149 1.000 35.98175 ? 546 HOH A O   1 
HETATM 2242 O O   . HOH C 3 .   ? 1.52319   -1.07026  3.24344  1.000 36.99325 ? 547 HOH A O   1 
HETATM 2243 O O   . HOH C 3 .   ? -6.75770  -19.05652 7.18048  1.000 44.57761 ? 548 HOH A O   1 
HETATM 2244 O O   . HOH C 3 .   ? -21.25401 8.46990   32.91561 1.000 60.65384 ? 549 HOH A O   1 
HETATM 2245 O O   . HOH C 3 .   ? 4.67730   18.78369  22.50230 1.000 45.21665 ? 550 HOH A O   1 
HETATM 2246 O O   . HOH C 3 .   ? 9.77743   -6.80615  24.85753 1.000 57.03072 ? 551 HOH A O   1 
HETATM 2247 O O   . HOH C 3 .   ? -10.01384 -3.65303  37.71637 1.000 45.85803 ? 552 HOH A O   1 
HETATM 2248 O O   . HOH C 3 .   ? 3.63481   2.24299   36.14288 1.000 33.36422 ? 553 HOH A O   1 
HETATM 2249 O O   . HOH C 3 .   ? -14.264   -18.738   18.415   1.000 45.94943 ? 554 HOH A O   1 
HETATM 2250 O O   . HOH C 3 .   ? 4.02766   17.51268  18.44299 1.000 44.51965 ? 555 HOH A O   1 
HETATM 2251 O O   . HOH C 3 .   ? 0.68858   -18.42479 16.19049 1.000 33.71368 ? 556 HOH A O   1 
HETATM 2252 O O   . HOH C 3 .   ? 10.41346  -2.84886  30.95400 1.000 46.30388 ? 557 HOH A O   1 
HETATM 2253 O O   . HOH C 3 .   ? 3.34518   8.76305   6.65988  1.000 60.81937 ? 558 HOH A O   1 
HETATM 2254 O O   . HOH C 3 .   ? 0.79071   18.70711  22.07370 1.000 47.37621 ? 559 HOH A O   1 
HETATM 2255 O O   . HOH C 3 .   ? -2.34930  -1.34048  0.61843  1.000 25.01732 ? 560 HOH A O   1 
HETATM 2256 O O   . HOH C 3 .   ? -0.41545  2.40352   1.38068  1.000 47.45062 ? 561 HOH A O   1 
HETATM 2257 O O   . HOH C 3 .   ? 7.74219   1.16198   17.94869 1.000 59.74824 ? 562 HOH A O   1 
HETATM 2258 O O   . HOH C 3 .   ? 9.47803   -9.60421  28.01385 1.000 39.55730 ? 563 HOH A O   1 
HETATM 2259 O O   . HOH C 3 .   ? 11.67052  -4.62733  23.83800 1.000 63.52669 ? 564 HOH A O   1 
HETATM 2260 O O   . HOH C 3 .   ? 4.38165   -0.10196  37.04332 1.000 46.43128 ? 565 HOH A O   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . SER A 1   ? 0.51575 0.98247 0.76421 -0.08634 -0.07109 -0.07066 28  SER A N   
2    C CA  . SER A 1   ? 0.50094 0.97995 0.72434 -0.05922 -0.09434 -0.06872 28  SER A CA  
3    C C   . SER A 1   ? 0.46540 0.90823 0.63268 -0.04953 -0.10581 -0.06671 28  SER A C   
4    O O   . SER A 1   ? 0.46965 0.87829 0.61551 -0.06065 -0.09560 -0.06405 28  SER A O   
5    C CB  . SER A 1   ? 0.48872 0.97573 0.71027 -0.03435 -0.08782 -0.05053 28  SER A CB  
6    O OG  . SER A 1   ? 0.49574 0.94577 0.68000 -0.02405 -0.07816 -0.03534 28  SER A OG  
7    N N   . ALA A 2   ? 0.51336 0.96218 0.65689 -0.02738 -0.12472 -0.06591 29  ALA A N   
8    C CA  . ALA A 2   ? 0.47087 0.88513 0.56142 -0.01563 -0.13291 -0.06215 29  ALA A CA  
9    C C   . ALA A 2   ? 0.34492 0.71862 0.40482 -0.00487 -0.11881 -0.04247 29  ALA A C   
10   O O   . ALA A 2   ? 0.35951 0.69795 0.38707 -0.00930 -0.11576 -0.04130 29  ALA A O   
11   C CB  . ALA A 2   ? 0.46993 0.89852 0.54180 0.00974  -0.15124 -0.06015 29  ALA A CB  
12   N N   A VAL A 3   ? 0.33497 0.71161 0.40540 0.00997  -0.11003 -0.02806 30  VAL A N   
13   N N   B VAL A 3   ? 0.33328 0.70989 0.40342 0.01022  -0.11020 -0.02803 30  VAL A N   
14   C CA  A VAL A 3   ? 0.29489 0.63244 0.34114 0.02175  -0.09825 -0.01181 30  VAL A CA  
15   C CA  B VAL A 3   ? 0.29086 0.62860 0.33739 0.02156  -0.09820 -0.01189 30  VAL A CA  
16   C C   A VAL A 3   ? 0.31419 0.63753 0.36556 0.00057  -0.08591 -0.01380 30  VAL A C   
17   C C   B VAL A 3   ? 0.31376 0.63692 0.36441 -0.00043 -0.08642 -0.01457 30  VAL A C   
18   O O   A VAL A 3   ? 0.30985 0.58948 0.33453 0.00347  -0.07849 -0.00600 30  VAL A O   
19   O O   B VAL A 3   ? 0.31354 0.59303 0.33631 0.00100  -0.07968 -0.00779 30  VAL A O   
20   C CB  A VAL A 3   ? 0.33759 0.67889 0.39461 0.04330  -0.09223 0.00030  30  VAL A CB  
21   C CB  B VAL A 3   ? 0.33500 0.67765 0.39428 0.04174  -0.09148 -0.00019 30  VAL A CB  
22   C CG1 A VAL A 3   ? 0.42359 0.76802 0.46747 0.06567  -0.10223 0.00575  30  VAL A CG1 
23   C CG1 B VAL A 3   ? 0.37560 0.67719 0.41796 0.05193  -0.07944 0.01178  30  VAL A CG1 
24   C CG2 A VAL A 3   ? 0.36824 0.74794 0.46621 0.03436  -0.08626 -0.00498 30  VAL A CG2 
25   C CG2 B VAL A 3   ? 0.42445 0.77748 0.47700 0.06302  -0.10195 0.00380  30  VAL A CG2 
26   N N   . GLN A 4   ? 0.28713 0.63824 0.37421 -0.02133 -0.07926 -0.02325 31  GLN A N   
27   C CA  . GLN A 4   ? 0.29496 0.60870 0.38070 -0.03994 -0.05892 -0.02161 31  GLN A CA  
28   C C   . GLN A 4   ? 0.25203 0.53464 0.31753 -0.05854 -0.05998 -0.03148 31  GLN A C   
29   O O   . GLN A 4   ? 0.28239 0.51714 0.32774 -0.06286 -0.04659 -0.02542 31  GLN A O   
30   C CB  . GLN A 4   ? 0.33200 0.67414 0.46045 -0.05565 -0.04385 -0.02449 31  GLN A CB  
31   C CG  . GLN A 4   ? 0.31161 0.65443 0.44355 -0.03709 -0.03049 -0.01005 31  GLN A CG  
32   C CD  . GLN A 4   ? 0.50517 0.89049 0.68230 -0.04523 -0.01729 -0.01124 31  GLN A CD  
33   O OE1 . GLN A 4   ? 0.50056 0.91838 0.71534 -0.06703 -0.01875 -0.02437 31  GLN A OE1 
34   N NE2 . GLN A 4   ? 0.45410 0.84077 0.63099 -0.02746 -0.00335 0.00077  31  GLN A NE2 
35   N N   . GLN A 5   ? 0.27587 0.58574 0.34519 -0.06703 -0.07709 -0.04811 32  GLN A N   
36   C CA  . GLN A 5   ? 0.35128 0.63095 0.39581 -0.08128 -0.07922 -0.05974 32  GLN A CA  
37   C C   . GLN A 5   ? 0.32638 0.56204 0.32171 -0.06171 -0.07927 -0.04673 32  GLN A C   
38   O O   . GLN A 5   ? 0.32001 0.51032 0.29431 -0.07059 -0.06812 -0.04646 32  GLN A O   
39   C CB  . GLN A 5   ? 0.41773 0.72587 0.47169 -0.08601 -0.09707 -0.08034 32  GLN A CB  
40   C CG  . GLN A 5   ? 0.61569 0.94898 0.72206 -0.10968 -0.09162 -0.09582 32  GLN A CG  
41   C CD  . GLN A 5   ? 0.92996 1.22872 1.04068 -0.13657 -0.07766 -0.10757 32  GLN A CD  
42   O OE1 . GLN A 5   ? 1.06128 1.34224 1.14893 -0.13951 -0.08689 -0.12133 32  GLN A OE1 
43   N NE2 . GLN A 5   ? 0.91595 1.20086 1.05371 -0.15306 -0.05317 -0.10015 32  GLN A NE2 
44   N N   . LYS A 6   ? 0.28475 0.53245 0.26468 -0.03449 -0.08953 -0.03527 33  LYS A N   
45   C CA  . LYS A 6   ? 0.29203 0.49623 0.23227 -0.01593 -0.08457 -0.02094 33  LYS A CA  
46   C C   . LYS A 6   ? 0.31752 0.47925 0.26155 -0.01538 -0.06532 -0.00833 33  LYS A C   
47   O O   . LYS A 6   ? 0.30290 0.42036 0.22570 -0.01505 -0.05522 -0.00358 33  LYS A O   
48   C CB  . LYS A 6   ? 0.27852 0.50024 0.20477 0.01446  -0.09581 -0.00931 33  LYS A CB  
49   C CG  . LYS A 6   ? 0.35618 0.59046 0.26410 0.02146  -0.11005 -0.01790 33  LYS A CG  
50   C CD  . LYS A 6   ? 0.41161 0.64939 0.30971 0.05150  -0.11340 -0.00216 33  LYS A CD  
51   C CE  . LYS A 6   ? 0.51907 0.75672 0.38277 0.06529  -0.12409 -0.00411 33  LYS A CE  
52   N NZ  . LYS A 6   ? 0.79767 1.04630 0.66016 0.09259  -0.12652 0.01016  33  LYS A NZ  
53   N N   . LEU A 7   ? 0.23586 0.41175 0.20714 -0.01351 -0.06023 -0.00407 34  LEU A N   
54   C CA  . LEU A 7   ? 0.20005 0.33933 0.17251 -0.01132 -0.04595 0.00333  34  LEU A CA  
55   C C   . LEU A 7   ? 0.23322 0.34379 0.20282 -0.03279 -0.03464 -0.00252 34  LEU A C   
56   O O   . LEU A 7   ? 0.24780 0.31880 0.20703 -0.03016 -0.02607 0.00163  34  LEU A O   
57   C CB  . LEU A 7   ? 0.20044 0.36096 0.19561 -0.00205 -0.04288 0.00728  34  LEU A CB  
58   C CG  . LEU A 7   ? 0.25256 0.43301 0.25193 0.02269  -0.05109 0.01420  34  LEU A CG  
59   C CD1 . LEU A 7   ? 0.28663 0.49539 0.30907 0.03035  -0.04769 0.01500  34  LEU A CD1 
60   C CD2 . LEU A 7   ? 0.27491 0.41521 0.26122 0.03952  -0.04734 0.02194  34  LEU A CD2 
61   N N   . ALA A 8   ? 0.24828 0.37817 0.23162 -0.05382 -0.03371 -0.01288 35  ALA A N   
62   C CA  . ALA A 8   ? 0.24939 0.34784 0.23075 -0.07316 -0.02044 -0.01718 35  ALA A CA  
63   C C   . ALA A 8   ? 0.26282 0.32713 0.21698 -0.07596 -0.02094 -0.02123 35  ALA A C   
64   O O   . ALA A 8   ? 0.26910 0.29430 0.21511 -0.08009 -0.00897 -0.01856 35  ALA A O   
65   C CB  . ALA A 8   ? 0.28401 0.40754 0.29213 -0.09680 -0.01662 -0.02881 35  ALA A CB  
66   N N   . ALA A 9   ? 0.26399 0.34359 0.20218 -0.07104 -0.03422 -0.02722 36  ALA A N   
67   C CA  . ALA A 9   ? 0.30079 0.34830 0.20689 -0.06903 -0.03246 -0.02931 36  ALA A CA  
68   C C   . ALA A 9   ? 0.28658 0.29836 0.18182 -0.05141 -0.02249 -0.01334 36  ALA A C   
69   O O   . ALA A 9   ? 0.30647 0.27970 0.18971 -0.05455 -0.01077 -0.01240 36  ALA A O   
70   C CB  . ALA A 9   ? 0.28147 0.35535 0.16529 -0.06046 -0.04949 -0.03720 36  ALA A CB  
71   N N   . LEU A 10  ? 0.25506 0.27949 0.15876 -0.03258 -0.02633 -0.00217 37  LEU A N   
72   C CA  . LEU A 10  ? 0.24261 0.23420 0.14740 -0.01788 -0.01643 0.00937  37  LEU A CA  
73   C C   . LEU A 10  ? 0.25582 0.22244 0.17598 -0.02651 -0.00665 0.00719  37  LEU A C   
74   O O   . LEU A 10  ? 0.30540 0.23765 0.22431 -0.02476 0.00339  0.00939  37  LEU A O   
75   C CB  . LEU A 10  ? 0.27313 0.28248 0.19119 0.00202  -0.02186 0.01820  37  LEU A CB  
76   C CG  . LEU A 10  ? 0.27076 0.24863 0.20329 0.01480  -0.01218 0.02508  37  LEU A CG  
77   C CD1 . LEU A 10  ? 0.34114 0.28699 0.25764 0.02166  -0.00088 0.03336  37  LEU A CD1 
78   C CD2 . LEU A 10  ? 0.28790 0.28348 0.23803 0.03298  -0.01759 0.02975  37  LEU A CD2 
79   N N   . GLU A 11  ? 0.22727 0.21176 0.16225 -0.03417 -0.00838 0.00352  38  GLU A N   
80   C CA  . GLU A 11  ? 0.25149 0.21432 0.19503 -0.03731 -0.00015 0.00323  38  GLU A CA  
81   C C   . GLU A 11  ? 0.27261 0.20522 0.20595 -0.05173 0.00944  -0.00091 38  GLU A C   
82   O O   . GLU A 11  ? 0.28737 0.19109 0.22371 -0.04742 0.01602  0.00043  38  GLU A O   
83   C CB  . GLU A 11  ? 0.19732 0.18406 0.15167 -0.04101 0.00030  0.00327  38  GLU A CB  
84   C CG  . GLU A 11  ? 0.25303 0.21850 0.20881 -0.03698 0.00816  0.00574  38  GLU A CG  
85   C CD  . GLU A 11  ? 0.27026 0.25507 0.23102 -0.03903 0.01440  0.00948  38  GLU A CD  
86   O OE1 . GLU A 11  ? 0.27148 0.26839 0.23858 -0.05758 0.02110  0.00783  38  GLU A OE1 
87   O OE2 . GLU A 11  ? 0.26602 0.25453 0.22590 -0.02122 0.01353  0.01303  38  GLU A OE2 
88   N N   . LYS A 12  ? 0.28622 0.22640 0.21029 -0.06806 0.00943  -0.00826 39  LYS A N   
89   C CA  . LYS A 12  ? 0.33132 0.24137 0.24521 -0.08188 0.01943  -0.01450 39  LYS A CA  
90   C C   . LYS A 12  ? 0.37149 0.25251 0.27130 -0.07280 0.02472  -0.01172 39  LYS A C   
91   O O   . LYS A 12  ? 0.39352 0.25466 0.29945 -0.06901 0.03374  -0.01115 39  LYS A O   
92   C CB  . LYS A 12  ? 0.31720 0.24404 0.22639 -0.10030 0.01567  -0.02798 39  LYS A CB  
93   C CG  . LYS A 12  ? 0.41147 0.30857 0.31500 -0.11527 0.02733  -0.03719 39  LYS A CG  
94   C CD  . LYS A 12  ? 0.61856 0.53669 0.52437 -0.13262 0.02090  -0.05533 39  LYS A CD  
95   C CE  . LYS A 12  ? 0.70413 0.60146 0.61242 -0.13478 0.03196  -0.06049 39  LYS A CE  
96   N NZ  . LYS A 12  ? 0.75853 0.67488 0.67251 -0.15029 0.02365  -0.08168 39  LYS A NZ  
97   N N   . SER A 13  ? 0.28552 0.17622 0.17369 -0.06043 0.01912  -0.00754 40  SER A N   
98   C CA  . SER A 13  ? 0.34956 0.21047 0.22515 -0.05081 0.02976  -0.00194 40  SER A CA  
99   C C   . SER A 13  ? 0.36491 0.20537 0.26699 -0.04095 0.03761  0.00491  40  SER A C   
100  O O   . SER A 13  ? 0.38903 0.22617 0.30285 -0.03253 0.04528  0.00557  40  SER A O   
101  C CB  . SER A 13  ? 0.38106 0.25394 0.23616 -0.03571 0.02538  0.00517  40  SER A CB  
102  O OG  . SER A 13  ? 0.33237 0.21655 0.20752 -0.02057 0.02166  0.01525  40  SER A OG  
103  N N   . SER A 14  ? 0.36074 0.21748 0.28572 -0.03532 0.02928  0.00577  41  SER A N   
104  C CA  . SER A 14  ? 0.31185 0.17661 0.27235 -0.02040 0.02662  0.00650  41  SER A CA  
105  C C   . SER A 14  ? 0.32367 0.20121 0.30352 -0.01941 0.02116  0.00194  41  SER A C   
106  O O   . SER A 14  ? 0.38419 0.26714 0.38183 -0.01144 0.01394  0.00026  41  SER A O   
107  C CB  . SER A 14  ? 0.29992 0.16927 0.26784 -0.01180 0.01927  0.00759  41  SER A CB  
108  O OG  . SER A 14  ? 0.31426 0.19947 0.28029 -0.01647 0.01278  0.00369  41  SER A OG  
109  N N   . GLY A 15  ? 0.30042 0.17789 0.26918 -0.02776 0.02340  0.00015  42  GLY A N   
110  C CA  . GLY A 15  ? 0.32525 0.20682 0.30426 -0.02468 0.02074  -0.00070 42  GLY A CA  
111  C C   . GLY A 15  ? 0.37449 0.25574 0.35942 -0.01716 0.01468  -0.00123 42  GLY A C   
112  O O   . GLY A 15  ? 0.38817 0.26634 0.37603 -0.01247 0.01307  -0.00150 42  GLY A O   
113  N N   . GLY A 16  ? 0.28417 0.16337 0.26607 -0.01381 0.01254  -0.00182 43  GLY A N   
114  C CA  . GLY A 16  ? 0.27759 0.15171 0.25831 -0.00045 0.00738  -0.00460 43  GLY A CA  
115  C C   . GLY A 16  ? 0.27273 0.16639 0.23646 -0.00274 0.00802  0.00083  43  GLY A C   
116  O O   . GLY A 16  ? 0.32824 0.22568 0.28176 -0.01955 0.01624  0.00524  43  GLY A O   
117  N N   . ARG A 17  ? 0.25033 0.16050 0.21548 0.01482  -0.00050 -0.00132 44  ARG A N   
118  C CA  . ARG A 17  ? 0.25242 0.18707 0.20649 0.01736  0.00167  0.00445  44  ARG A CA  
119  C C   . ARG A 17  ? 0.28249 0.23966 0.24699 0.02927  -0.00867 -0.00030 44  ARG A C   
120  O O   . ARG A 17  ? 0.23712 0.19128 0.21151 0.04669  -0.01904 -0.00985 44  ARG A O   
121  C CB  . ARG A 17  ? 0.25115 0.18173 0.18880 0.03269  0.00475  0.00826  44  ARG A CB  
122  C CG  . ARG A 17  ? 0.26843 0.22246 0.19467 0.03627  0.01321  0.01706  44  ARG A CG  
123  C CD  . ARG A 17  ? 0.28713 0.23220 0.18873 0.05345  0.02238  0.02608  44  ARG A CD  
124  N NE  . ARG A 17  ? 0.31024 0.25342 0.20137 0.08275  0.00612  0.01602  44  ARG A NE  
125  C CZ  . ARG A 17  ? 0.28870 0.24980 0.16558 0.10631  0.00048  0.01269  44  ARG A CZ  
126  N NH1 . ARG A 17  ? 0.32088 0.30297 0.19227 0.10542  0.01263  0.02169  44  ARG A NH1 
127  N NH2 . ARG A 17  ? 0.34286 0.30247 0.21244 0.13264  -0.01809 -0.00209 44  ARG A NH2 
128  N N   . LEU A 18  ? 0.21244 0.19262 0.17829 0.02033  -0.00648 0.00441  45  LEU A N   
129  C CA  . LEU A 18  ? 0.20428 0.20493 0.18071 0.03058  -0.01445 0.00231  45  LEU A CA  
130  C C   . LEU A 18  ? 0.22615 0.25760 0.19979 0.03802  -0.01232 0.00567  45  LEU A C   
131  O O   . LEU A 18  ? 0.22467 0.27001 0.19552 0.02491  -0.00270 0.01211  45  LEU A O   
132  C CB  . LEU A 18  ? 0.20176 0.20656 0.18100 0.01828  -0.01466 0.00568  45  LEU A CB  
133  C CG  . LEU A 18  ? 0.20607 0.23285 0.19353 0.02940  -0.02121 0.00756  45  LEU A CG  
134  C CD1 . LEU A 18  ? 0.24983 0.25582 0.25039 0.04528  -0.02446 0.00345  45  LEU A CD1 
135  C CD2 . LEU A 18  ? 0.26143 0.29703 0.24218 0.01918  -0.02227 0.01209  45  LEU A CD2 
136  N N   . GLY A 19  ? 0.19447 0.23645 0.17281 0.05850  -0.01940 0.00032  46  GLY A N   
137  C CA  . GLY A 19  ? 0.21939 0.29189 0.19614 0.06834  -0.01575 0.00347  46  GLY A CA  
138  C C   . GLY A 19  ? 0.24463 0.33478 0.23672 0.07946  -0.02345 0.00061  46  GLY A C   
139  O O   . GLY A 19  ? 0.23835 0.31222 0.23888 0.09136  -0.03166 -0.00770 46  GLY A O   
140  N N   . VAL A 20  ? 0.19070 0.31360 0.19106 0.07599  -0.02016 0.00699  47  VAL A N   
141  C CA  . VAL A 20  ? 0.17328 0.31503 0.18803 0.08743  -0.02690 0.00721  47  VAL A CA  
142  C C   . VAL A 20  ? 0.22680 0.40541 0.24850 0.09796  -0.02138 0.00940  47  VAL A C   
143  O O   . VAL A 20  ? 0.24401 0.44388 0.26846 0.08599  -0.01126 0.01479  47  VAL A O   
144  C CB  . VAL A 20  ? 0.19847 0.34900 0.21881 0.07411  -0.03127 0.01313  47  VAL A CB  
145  C CG1 . VAL A 20  ? 0.21922 0.38714 0.25074 0.09067  -0.03738 0.01617  47  VAL A CG1 
146  C CG2 . VAL A 20  ? 0.21002 0.32370 0.22126 0.06486  -0.03244 0.01247  47  VAL A CG2 
147  N N   . ALA A 21  ? 0.19840 0.37368 0.22261 0.11364  -0.02345 0.00432  48  ALA A N   
148  C CA  . ALA A 21  ? 0.19075 0.39862 0.22314 0.12111  -0.01752 0.00719  48  ALA A CA  
149  C C   . ALA A 21  ? 0.19462 0.39447 0.23518 0.12627  -0.02284 0.00608  48  ALA A C   
150  O O   . ALA A 21  ? 0.25851 0.42537 0.29595 0.13161  -0.02621 -0.00044 48  ALA A O   
151  C CB  . ALA A 21  ? 0.20252 0.40979 0.21934 0.13649  -0.00935 0.00258  48  ALA A CB  
152  N N   . LEU A 22  ? 0.17579 0.40864 0.23103 0.12470  -0.02305 0.01242  49  LEU A N   
153  C CA  . LEU A 22  ? 0.21775 0.44987 0.28091 0.13347  -0.02686 0.01417  49  LEU A CA  
154  C C   . LEU A 22  ? 0.23494 0.49944 0.30920 0.14273  -0.02084 0.01453  49  LEU A C   
155  O O   . LEU A 22  ? 0.24430 0.54554 0.33084 0.13641  -0.01564 0.01749  49  LEU A O   
156  C CB  . LEU A 22  ? 0.21270 0.45604 0.28116 0.12670  -0.03502 0.02102  49  LEU A CB  
157  C CG  . LEU A 22  ? 0.25556 0.50649 0.33193 0.13971  -0.03822 0.02523  49  LEU A CG  
158  C CD1 . LEU A 22  ? 0.30961 0.51976 0.37934 0.14867  -0.03849 0.02782  49  LEU A CD1 
159  C CD2 . LEU A 22  ? 0.34147 0.62568 0.42489 0.13492  -0.04675 0.02934  49  LEU A CD2 
160  N N   . ILE A 23  ? 0.22190 0.47402 0.29626 0.15697  -0.01979 0.01137  50  ILE A N   
161  C CA  . ILE A 23  ? 0.22700 0.50965 0.31465 0.16767  -0.01472 0.01287  50  ILE A CA  
162  C C   . ILE A 23  ? 0.25857 0.53907 0.35709 0.17537  -0.02120 0.01699  50  ILE A C   
163  O O   . ILE A 23  ? 0.28189 0.52803 0.37558 0.18099  -0.02360 0.01551  50  ILE A O   
164  C CB  . ILE A 23  ? 0.27539 0.54931 0.35173 0.18131  -0.00658 0.00545  50  ILE A CB  
165  C CG1 . ILE A 23  ? 0.23677 0.51146 0.29631 0.17752  0.00021  0.00375  50  ILE A CG1 
166  C CG2 . ILE A 23  ? 0.29146 0.59778 0.38461 0.19349  0.00008  0.00818  50  ILE A CG2 
167  C CD1 . ILE A 23  ? 0.36883 0.62452 0.40421 0.19305  0.00422  -0.00613 50  ILE A CD1 
168  N N   . ASP A 24  ? 0.24748 0.56572 0.36389 0.17559  -0.02402 0.02235  51  ASP A N   
169  C CA  . ASP A 24  ? 0.31805 0.64077 0.44374 0.18723  -0.03018 0.02750  51  ASP A CA  
170  C C   . ASP A 24  ? 0.31440 0.65374 0.45401 0.20211  -0.02307 0.02560  51  ASP A C   
171  O O   . ASP A 24  ? 0.31452 0.69256 0.47178 0.20077  -0.01839 0.02519  51  ASP A O   
172  C CB  . ASP A 24  ? 0.31756 0.67409 0.45430 0.18038  -0.04054 0.03192  51  ASP A CB  
173  C CG  . ASP A 24  ? 0.49909 0.85994 0.63941 0.19570  -0.04839 0.03855  51  ASP A CG  
174  O OD1 . ASP A 24  ? 0.40381 0.75122 0.54697 0.21120  -0.04335 0.04014  51  ASP A OD1 
175  O OD2 . ASP A 24  ? 0.41350 0.79105 0.55269 0.19368  -0.05976 0.04177  51  ASP A OD2 
176  N N   . THR A 25  ? 0.42014 0.65231 0.52237 0.18167  -0.13552 -0.07102 52  THR A N   
177  C CA  . THR A 25  ? 0.37300 0.62982 0.49954 0.18925  -0.12974 -0.07788 52  THR A CA  
178  C C   . THR A 25  ? 0.43669 0.70779 0.57934 0.20069  -0.14492 -0.08788 52  THR A C   
179  O O   . THR A 25  ? 0.55762 0.85193 0.72373 0.20757  -0.14127 -0.09477 52  THR A O   
180  C CB  . THR A 25  ? 0.36951 0.59801 0.46966 0.19875  -0.12225 -0.07290 52  THR A CB  
181  O OG1 . THR A 25  ? 0.46497 0.65479 0.53014 0.21220  -0.13510 -0.07163 52  THR A OG1 
182  C CG2 . THR A 25  ? 0.32712 0.53853 0.41057 0.18818  -0.10849 -0.06288 52  THR A CG2 
183  N N   . ALA A 26  ? 0.40318 0.66095 0.53422 0.20285  -0.16182 -0.08918 53  ALA A N   
184  C CA  . ALA A 26  ? 0.41751 0.68920 0.56517 0.21387  -0.17799 -0.09937 53  ALA A CA  
185  C C   . ALA A 26  ? 0.53129 0.85552 0.73153 0.20450  -0.17430 -0.10795 53  ALA A C   
186  O O   . ALA A 26  ? 0.56784 0.91706 0.79559 0.21337  -0.17743 -0.11718 53  ALA A O   
187  C CB  . ALA A 26  ? 0.43227 0.67205 0.55025 0.21780  -0.19688 -0.09827 53  ALA A CB  
188  N N   . ASP A 27  ? 0.44035 0.78107 0.65500 0.18601  -0.16708 -0.10531 54  ASP A N   
189  C CA  . ASP A 27  ? 0.46840 0.85565 0.73051 0.17358  -0.16121 -0.11269 54  ASP A CA  
190  C C   . ASP A 27  ? 0.45556 0.85886 0.72994 0.15478  -0.13914 -0.10811 54  ASP A C   
191  O O   . ASP A 27  ? 0.43372 0.86929 0.74120 0.13987  -0.13233 -0.11244 54  ASP A O   
192  C CB  . ASP A 27  ? 0.44030 0.83273 0.71013 0.16801  -0.17807 -0.11633 54  ASP A CB  
193  C CG  . ASP A 27  ? 0.57677 0.93301 0.80782 0.16192  -0.18414 -0.10724 54  ASP A CG  
194  O OD1 . ASP A 27  ? 0.45268 0.78723 0.65856 0.15849  -0.17254 -0.09833 54  ASP A OD1 
195  O OD2 . ASP A 27  ? 0.52207 0.87030 0.74695 0.16068  -0.20035 -0.10903 54  ASP A OD2 
196  N N   . ASN A 28  ? 0.44038 0.81979 0.68744 0.15471  -0.12792 -0.09953 55  ASN A N   
197  C CA  . ASN A 28  ? 0.43683 0.82559 0.68948 0.13816  -0.10754 -0.09472 55  ASN A CA  
198  C C   . ASN A 28  ? 0.43904 0.83383 0.69617 0.11900  -0.10753 -0.09241 55  ASN A C   
199  O O   . ASN A 28  ? 0.55829 0.97133 0.83162 0.10189  -0.09136 -0.09185 55  ASN A O   
200  C CB  . ASN A 28  ? 0.43168 0.85331 0.71732 0.13415  -0.09041 -0.10068 55  ASN A CB  
201  C CG  . ASN A 28  ? 0.69020 1.10321 0.96799 0.15171  -0.08785 -0.10198 55  ASN A CG  
202  O OD1 . ASN A 28  ? 0.60759 0.98670 0.85104 0.16275  -0.09273 -0.09585 55  ASN A OD1 
203  N ND2 . ASN A 28  ? 0.68862 1.13068 0.99740 0.15411  -0.07985 -0.10998 55  ASN A ND2 
204  N N   . THR A 29  ? 0.44713 0.82372 0.68720 0.12119  -0.12528 -0.09106 56  THR A N   
205  C CA  . THR A 29  ? 0.32103 0.69802 0.55982 0.10333  -0.12598 -0.08820 56  THR A CA  
206  C C   . THR A 29  ? 0.27979 0.62891 0.48674 0.09814  -0.11836 -0.07806 56  THR A C   
207  O O   . THR A 29  ? 0.31852 0.64252 0.50028 0.11042  -0.11676 -0.07282 56  THR A O   
208  C CB  . THR A 29  ? 0.36904 0.73503 0.59947 0.10698  -0.14793 -0.09072 56  THR A CB  
209  O OG1 . THR A 29  ? 0.42357 0.74905 0.61409 0.12398  -0.16043 -0.08622 56  THR A OG1 
210  C CG2 . THR A 29  ? 0.42175 0.81967 0.68893 0.11080  -0.15611 -0.10155 56  THR A CG2 
211  N N   . GLN A 30  ? 0.27263 0.62647 0.48176 0.07906  -0.11282 -0.07548 57  GLN A N   
212  C CA  . GLN A 30  ? 0.32137 0.65075 0.50402 0.07029  -0.10274 -0.06586 57  GLN A CA  
213  C C   . GLN A 30  ? 0.32708 0.63487 0.49010 0.05793  -0.10971 -0.06170 57  GLN A C   
214  O O   . GLN A 30  ? 0.35795 0.68862 0.54145 0.04962  -0.11844 -0.06843 57  GLN A O   
215  C CB  . GLN A 30  ? 0.30295 0.64722 0.50008 0.05404  -0.07964 -0.06376 57  GLN A CB  
216  C CG  . GLN A 30  ? 0.37921 0.73572 0.58708 0.06497  -0.06933 -0.06597 57  GLN A CG  
217  C CD  . GLN A 30  ? 0.54757 0.90832 0.75952 0.04915  -0.04685 -0.06261 57  GLN A CD  
218  O OE1 . GLN A 30  ? 0.46673 0.81674 0.66989 0.03054  -0.03912 -0.05744 57  GLN A OE1 
219  N NE2 . GLN A 30  ? 0.64966 1.02334 0.87230 0.05725  -0.03665 -0.06573 57  GLN A NE2 
220  N N   . VAL A 31  ? 0.25996 0.52314 0.38370 0.05664  -0.10561 -0.05111 58  VAL A N   
221  C CA  . VAL A 31  ? 0.24224 0.48103 0.34446 0.04336  -0.10728 -0.04606 58  VAL A CA  
222  C C   . VAL A 31  ? 0.26013 0.47766 0.34746 0.03020  -0.08758 -0.03656 58  VAL A C   
223  O O   . VAL A 31  ? 0.29397 0.49015 0.36509 0.03763  -0.07998 -0.03086 58  VAL A O   
224  C CB  . VAL A 31  ? 0.30290 0.50320 0.36867 0.05562  -0.12272 -0.04330 58  VAL A CB  
225  C CG1 . VAL A 31  ? 0.38963 0.56102 0.43022 0.04127  -0.12057 -0.03742 58  VAL A CG1 
226  C CG2 . VAL A 31  ? 0.33350 0.55224 0.41220 0.06942  -0.14572 -0.05337 58  VAL A CG2 
227  N N   . LEU A 32  ? 0.22943 0.45309 0.32338 0.01096  -0.08009 -0.03548 59  LEU A N   
228  C CA  . LEU A 32  ? 0.25914 0.46642 0.34317 -0.00149 -0.06283 -0.02794 59  LEU A CA  
229  C C   . LEU A 32  ? 0.25771 0.44031 0.32189 -0.01440 -0.06251 -0.02331 59  LEU A C   
230  O O   . LEU A 32  ? 0.25750 0.44871 0.32619 -0.02123 -0.07177 -0.02742 59  LEU A O   
231  C CB  . LEU A 32  ? 0.22053 0.45797 0.33113 -0.01336 -0.05006 -0.03102 59  LEU A CB  
232  C CG  . LEU A 32  ? 0.21159 0.47551 0.34374 -0.00212 -0.04699 -0.03633 59  LEU A CG  
233  C CD1 . LEU A 32  ? 0.31905 0.61624 0.47924 -0.01586 -0.03565 -0.04176 59  LEU A CD1 
234  C CD2 . LEU A 32  ? 0.27908 0.51934 0.39343 0.00740  -0.03917 -0.02999 59  LEU A CD2 
235  N N   . TYR A 33  ? 0.23619 0.38812 0.27951 -0.01741 -0.05206 -0.01534 60  TYR A N   
236  C CA  . TYR A 33  ? 0.22664 0.35425 0.25221 -0.02963 -0.04857 -0.01083 60  TYR A CA  
237  C C   . TYR A 33  ? 0.23402 0.35152 0.25854 -0.03737 -0.03373 -0.00556 60  TYR A C   
238  O O   . TYR A 33  ? 0.23094 0.33234 0.24737 -0.02908 -0.02848 -0.00163 60  TYR A O   
239  C CB  . TYR A 33  ? 0.24401 0.33528 0.23908 -0.02177 -0.05400 -0.00708 60  TYR A CB  
240  C CG  . TYR A 33  ? 0.24477 0.31327 0.22323 -0.03432 -0.05024 -0.00374 60  TYR A CG  
241  C CD1 . TYR A 33  ? 0.26395 0.33797 0.24141 -0.04226 -0.05955 -0.00748 60  TYR A CD1 
242  C CD2 . TYR A 33  ? 0.24826 0.29080 0.21418 -0.03835 -0.03762 0.00242  60  TYR A CD2 
243  C CE1 . TYR A 33  ? 0.29687 0.34908 0.25805 -0.05346 -0.05579 -0.00467 60  TYR A CE1 
244  C CE2 . TYR A 33  ? 0.26761 0.28995 0.21980 -0.04888 -0.03369 0.00478  60  TYR A CE2 
245  C CZ  . TYR A 33  ? 0.32004 0.34636 0.26825 -0.05622 -0.04264 0.00143  60  TYR A CZ  
246  O OH  . TYR A 33  ? 0.33780 0.34251 0.27037 -0.06597 -0.03912 0.00347  60  TYR A OH  
247  N N   . ARG A 34  ? 0.19173 0.31721 0.22365 -0.05316 -0.02796 -0.00587 61  ARG A N   
248  C CA  . ARG A 34  ? 0.20803 0.32632 0.24007 -0.06028 -0.01594 -0.00213 61  ARG A CA  
249  C C   . ARG A 34  ? 0.24235 0.37464 0.28600 -0.05144 -0.01163 -0.00318 61  ARG A C   
250  O O   . ARG A 34  ? 0.18944 0.30589 0.22647 -0.04837 -0.00522 0.00081  61  ARG A O   
251  C CB  . ARG A 34  ? 0.20346 0.28666 0.21576 -0.06072 -0.01133 0.00409  61  ARG A CB  
252  C CG  . ARG A 34  ? 0.23186 0.29781 0.23005 -0.06924 -0.01396 0.00509  61  ARG A CG  
253  C CD  . ARG A 34  ? 0.23132 0.26633 0.21571 -0.07082 -0.00661 0.01018  61  ARG A CD  
254  N NE  . ARG A 34  ? 0.25310 0.26890 0.22203 -0.07691 -0.00799 0.01096  61  ARG A NE  
255  C CZ  . ARG A 34  ? 0.33460 0.35049 0.30148 -0.08978 -0.00821 0.01006  61  ARG A CZ  
256  N NH1 . ARG A 34  ? 0.30811 0.34049 0.28645 -0.09930 -0.00591 0.00870  61  ARG A NH1 
257  N NH2 . ARG A 34  ? 0.32816 0.32470 0.27840 -0.09347 -0.01035 0.01042  61  ARG A NH2 
258  N N   . GLY A 35  ? 0.18706 0.34960 0.24920 -0.04693 -0.01586 -0.00936 62  GLY A N   
259  C CA  . GLY A 35  ? 0.19641 0.37311 0.26928 -0.03625 -0.01256 -0.01142 62  GLY A CA  
260  C C   . GLY A 35  ? 0.21493 0.39310 0.29049 -0.04369 -0.00015 -0.01016 62  GLY A C   
261  O O   . GLY A 35  ? 0.19752 0.37417 0.27276 -0.03418 0.00347  -0.00964 62  GLY A O   
262  N N   . ASP A 36  ? 0.18619 0.36393 0.26111 -0.06021 0.00597  -0.00969 63  ASP A N   
263  C CA  . ASP A 36  ? 0.16597 0.34049 0.23820 -0.06783 0.01736  -0.00860 63  ASP A CA  
264  C C   . ASP A 36  ? 0.23679 0.37799 0.28833 -0.07459 0.02003  -0.00218 63  ASP A C   
265  O O   . ASP A 36  ? 0.26293 0.39628 0.30743 -0.08339 0.02776  -0.00118 63  ASP A O   
266  C CB  . ASP A 36  ? 0.19288 0.39273 0.28003 -0.08198 0.02405  -0.01408 63  ASP A CB  
267  C CG  . ASP A 36  ? 0.27797 0.51459 0.39125 -0.07472 0.02305  -0.02197 63  ASP A CG  
268  O OD1 . ASP A 36  ? 0.26770 0.50919 0.38441 -0.06138 0.02495  -0.02303 63  ASP A OD1 
269  O OD2 . ASP A 36  ? 0.33916 0.59982 0.47056 -0.08170 0.01938  -0.02768 63  ASP A OD2 
270  N N   . GLU A 37  ? 0.18876 0.30892 0.22975 -0.07058 0.01407  0.00169  64  GLU A N   
271  C CA  . GLU A 37  ? 0.17932 0.26929 0.20502 -0.07420 0.01606  0.00676  64  GLU A CA  
272  C C   . GLU A 37  ? 0.22235 0.29788 0.24412 -0.06245 0.01651  0.00928  64  GLU A C   
273  O O   . GLU A 37  ? 0.20542 0.28585 0.23120 -0.05023 0.01351  0.00869  64  GLU A O   
274  C CB  . GLU A 37  ? 0.19953 0.27298 0.21714 -0.07612 0.01143  0.00902  64  GLU A CB  
275  C CG  . GLU A 37  ? 0.21384 0.29610 0.23195 -0.08908 0.00992  0.00678  64  GLU A CG  
276  C CD  . GLU A 37  ? 0.21490 0.27607 0.22080 -0.09177 0.00654  0.00910  64  GLU A CD  
277  O OE1 . GLU A 37  ? 0.24438 0.28219 0.24195 -0.08717 0.00811  0.01259  64  GLU A OE1 
278  O OE2 . GLU A 37  ? 0.25364 0.32246 0.25949 -0.09864 0.00250  0.00675  64  GLU A OE2 
279  N N   . ARG A 38  ? 0.20107 0.25581 0.21358 -0.06604 0.01898  0.01195  65  ARG A N   
280  C CA  . ARG A 38  ? 0.18996 0.22878 0.19960 -0.05597 0.01795  0.01392  65  ARG A CA  
281  C C   . ARG A 38  ? 0.21089 0.23206 0.21979 -0.05094 0.01481  0.01633  65  ARG A C   
282  O O   . ARG A 38  ? 0.22128 0.23239 0.22713 -0.05729 0.01442  0.01741  65  ARG A O   
283  C CB  . ARG A 38  ? 0.21634 0.23795 0.21608 -0.06096 0.01966  0.01502  65  ARG A CB  
284  C CG  . ARG A 38  ? 0.30265 0.33810 0.30053 -0.06318 0.02519  0.01257  65  ARG A CG  
285  C CD  . ARG A 38  ? 0.34944 0.36361 0.33252 -0.06432 0.02617  0.01360  65  ARG A CD  
286  N NE  . ARG A 38  ? 0.39923 0.42547 0.37880 -0.06525 0.03376  0.01095  65  ARG A NE  
287  C CZ  . ARG A 38  ? 0.37003 0.39964 0.34998 -0.05479 0.03505  0.00964  65  ARG A CZ  
288  N NH1 . ARG A 38  ? 0.24754 0.26905 0.23091 -0.04273 0.02854  0.01092  65  ARG A NH1 
289  N NH2 . ARG A 38  ? 0.42649 0.46675 0.40275 -0.05687 0.04409  0.00667  65  ARG A NH2 
290  N N   . PHE A 39  ? 0.18687 0.20311 0.19789 -0.03974 0.01363  0.01687  66  PHE A N   
291  C CA  . PHE A 39  ? 0.18465 0.18272 0.19554 -0.03504 0.01313  0.01873  66  PHE A CA  
292  C C   . PHE A 39  ? 0.17239 0.15780 0.18531 -0.02846 0.01242  0.01920  66  PHE A C   
293  O O   . PHE A 39  ? 0.18383 0.17688 0.19583 -0.02320 0.01170  0.01818  66  PHE A O   
294  C CB  . PHE A 39  ? 0.18792 0.19042 0.19681 -0.02751 0.01222  0.01858  66  PHE A CB  
295  C CG  . PHE A 39  ? 0.15603 0.16590 0.16149 -0.03266 0.01089  0.01789  66  PHE A CG  
296  C CD1 . PHE A 39  ? 0.17197 0.20570 0.18158 -0.03564 0.00839  0.01510  66  PHE A CD1 
297  C CD2 . PHE A 39  ? 0.18415 0.17669 0.18263 -0.03442 0.01244  0.01942  66  PHE A CD2 
298  C CE1 . PHE A 39  ? 0.20255 0.24291 0.20958 -0.04072 0.00520  0.01378  66  PHE A CE1 
299  C CE2 . PHE A 39  ? 0.19595 0.19224 0.18785 -0.03903 0.01005  0.01861  66  PHE A CE2 
300  C CZ  . PHE A 39  ? 0.18691 0.20718 0.18338 -0.04204 0.00537  0.01578  66  PHE A CZ  
301  N N   . PRO A 40  ? 0.19107 0.15754 0.20782 -0.02825 0.01273  0.02009  67  PRO A N   
302  C CA  . PRO A 40  ? 0.19403 0.14849 0.21516 -0.02201 0.01090  0.01981  67  PRO A CA  
303  C C   . PRO A 40  ? 0.20186 0.15819 0.22071 -0.01249 0.01194  0.02006  67  PRO A C   
304  O O   . PRO A 40  ? 0.19279 0.14710 0.20875 -0.01064 0.01483  0.02086  67  PRO A O   
305  C CB  . PRO A 40  ? 0.23341 0.17053 0.26414 -0.02492 0.01196  0.01958  67  PRO A CB  
306  C CG  . PRO A 40  ? 0.25921 0.19749 0.28791 -0.03249 0.01472  0.02001  67  PRO A CG  
307  C CD  . PRO A 40  ? 0.21362 0.16955 0.23225 -0.03411 0.01506  0.02064  67  PRO A CD  
308  N N   . MET A 41  ? 0.17141 0.12887 0.18812 -0.00614 0.00935  0.01930  68  MET A N   
309  C CA  . MET A 41  ? 0.16313 0.12097 0.17528 0.00399  0.00945  0.01928  68  MET A CA  
310  C C   . MET A 41  ? 0.20125 0.13918 0.21596 0.00663  0.01128  0.02006  68  MET A C   
311  O O   . MET A 41  ? 0.21485 0.14809 0.22220 0.01288  0.01312  0.02080  68  MET A O   
312  C CB  . MET A 41  ? 0.18713 0.14923 0.19520 0.00997  0.00675  0.01790  68  MET A CB  
313  C CG  . MET A 41  ? 0.22567 0.21061 0.23141 0.00978  0.00785  0.01635  68  MET A CG  
314  S SD  . MET A 41  ? 0.22279 0.21144 0.22209 0.01727  0.00751  0.01411  68  MET A SD  
315  C CE  . MET A 41  ? 0.22669 0.19625 0.22109 0.00966  0.00537  0.01462  68  MET A CE  
316  N N   . CYS A 42  ? 0.20216 0.12717 0.22700 0.00231  0.01040  0.01939  69  CYS A N   
317  C CA  . CYS A 42  ? 0.17941 0.08682 0.21097 0.00418  0.01239  0.01892  69  CYS A CA  
318  C C   . CYS A 42  ? 0.20834 0.11164 0.22960 0.01363  0.01102  0.01917  69  CYS A C   
319  O O   . CYS A 42  ? 0.20807 0.11852 0.22304 0.01848  0.00616  0.01851  69  CYS A O   
320  C CB  . CYS A 42  ? 0.21134 0.11066 0.24619 -0.00016 0.02056  0.01967  69  CYS A CB  
321  S SG  . CYS A 42  ? 0.25067 0.15701 0.29452 -0.00976 0.02050  0.01795  69  CYS A SG  
322  N N   . SER A 43  ? 0.19598 0.08502 0.21357 0.01641  0.01583  0.01990  70  SER A N   
323  C CA  . SER A 43  ? 0.22092 0.10138 0.22783 0.02535  0.01364  0.01989  70  SER A CA  
324  C C   . SER A 43  ? 0.22465 0.11767 0.21577 0.03469  0.01075  0.02043  70  SER A C   
325  O O   . SER A 43  ? 0.23345 0.11995 0.21501 0.04343  0.00803  0.01998  70  SER A O   
326  C CB  . SER A 43  ? 0.27711 0.14205 0.28001 0.02420  0.01799  0.01938  70  SER A CB  
327  O OG  . SER A 43  ? 0.34811 0.21396 0.36403 0.01618  0.01511  0.01549  70  SER A OG  
328  N N   . THR A 44  ? 0.19720 0.10805 0.18646 0.03349  0.01070  0.02071  71  THR A N   
329  C CA  . THR A 44  ? 0.19148 0.11813 0.17159 0.04287  0.00687  0.01966  71  THR A CA  
330  C C   . THR A 44  ? 0.20056 0.13772 0.18324 0.04633  0.00359  0.01761  71  THR A C   
331  O O   . THR A 44  ? 0.25258 0.19814 0.22848 0.05661  0.00121  0.01591  71  THR A O   
332  C CB  . THR A 44  ? 0.20333 0.14896 0.18432 0.04004  0.00648  0.01931  71  THR A CB  
333  O OG1 . THR A 44  ? 0.21470 0.17445 0.20705 0.03002  0.00725  0.01875  71  THR A OG1 
334  C CG2 . THR A 44  ? 0.24671 0.17714 0.21902 0.03802  0.00955  0.02128  71  THR A CG2 
335  N N   . SER A 45  ? 0.21160 0.14485 0.20195 0.03908  0.00318  0.01740  72  SER A N   
336  C CA  . SER A 45  ? 0.18742 0.12343 0.17478 0.04199  0.00046  0.01562  72  SER A CA  
337  C C   . SER A 45  ? 0.21462 0.13508 0.19294 0.05181  -0.00226 0.01491  72  SER A C   
338  O O   . SER A 45  ? 0.24075 0.16377 0.21179 0.05763  -0.00380 0.01308  72  SER A O   
339  C CB  . SER A 45  ? 0.18603 0.11433 0.17963 0.03243  -0.00147 0.01558  72  SER A CB  
340  O OG  . SER A 45  ? 0.27005 0.17864 0.27110 0.02966  -0.00334 0.01595  72  SER A OG  
341  N N   A LYS A 46  ? 0.23603 0.13879 0.21265 0.05373  -0.00189 0.01614  73  LYS A N   
342  N N   B LYS A 46  ? 0.23593 0.13854 0.21279 0.05351  -0.00188 0.01615  73  LYS A N   
343  C CA  A LYS A 46  ? 0.24754 0.13254 0.21401 0.06228  -0.00457 0.01548  73  LYS A CA  
344  C CA  B LYS A 46  ? 0.24778 0.13271 0.21436 0.06217  -0.00447 0.01554  73  LYS A CA  
345  C C   A LYS A 46  ? 0.26499 0.15889 0.21833 0.07550  -0.00558 0.01421  73  LYS A C   
346  C C   B LYS A 46  ? 0.26411 0.15880 0.21787 0.07522  -0.00558 0.01416  73  LYS A C   
347  O O   A LYS A 46  ? 0.27690 0.16017 0.22009 0.08380  -0.00838 0.01286  73  LYS A O   
348  O O   B LYS A 46  ? 0.27288 0.15844 0.21717 0.08306  -0.00838 0.01266  73  LYS A O   
349  C CB  A LYS A 46  ? 0.26850 0.13346 0.23647 0.05886  -0.00200 0.01679  73  LYS A CB  
350  C CB  B LYS A 46  ? 0.26750 0.13263 0.23416 0.05965  -0.00165 0.01697  73  LYS A CB  
351  C CG  A LYS A 46  ? 0.26592 0.12778 0.25457 0.04536  -0.00198 0.01584  73  LYS A CG  
352  C CG  B LYS A 46  ? 0.27580 0.13661 0.26285 0.04602  -0.00141 0.01595  73  LYS A CG  
353  C CD  A LYS A 46  ? 0.27022 0.12569 0.26690 0.03758  0.00185  0.01547  73  LYS A CD  
354  C CD  B LYS A 46  ? 0.24954 0.10194 0.24234 0.03974  0.00187  0.01544  73  LYS A CD  
355  C CE  A LYS A 46  ? 0.24109 0.09213 0.24504 0.02807  -0.00239 0.01174  73  LYS A CE  
356  C CE  B LYS A 46  ? 0.24992 0.09866 0.25464 0.02966  -0.00338 0.01168  73  LYS A CE  
357  N NZ  A LYS A 46  ? 0.28496 0.13434 0.29472 0.02005  0.00429  0.01117  73  LYS A NZ  
358  N NZ  B LYS A 46  ? 0.25985 0.11493 0.26756 0.02447  -0.00021 0.01158  73  LYS A NZ  
359  N N   . VAL A 47  ? 0.22355 0.13630 0.17733 0.07836  -0.00422 0.01399  74  VAL A N   
360  C CA  . VAL A 47  ? 0.26670 0.19162 0.21266 0.09194  -0.00634 0.01138  74  VAL A CA  
361  C C   . VAL A 47  ? 0.28746 0.22541 0.23520 0.09450  -0.00562 0.00837  74  VAL A C   
362  O O   . VAL A 47  ? 0.27800 0.21365 0.21657 0.10640  -0.00702 0.00595  74  VAL A O   
363  C CB  . VAL A 47  ? 0.26896 0.21471 0.21912 0.09383  -0.00689 0.01051  74  VAL A CB  
364  C CG1 . VAL A 47  ? 0.35635 0.31883 0.30399 0.10869  -0.01020 0.00627  74  VAL A CG1 
365  C CG2 . VAL A 47  ? 0.34737 0.27390 0.28854 0.09255  -0.00720 0.01359  74  VAL A CG2 
366  N N   A MET A 48  ? 0.25485 0.20453 0.21196 0.08360  -0.00277 0.00831  75  MET A N   
367  N N   B MET A 48  ? 0.25488 0.20406 0.21183 0.08360  -0.00281 0.00833  75  MET A N   
368  C CA  A MET A 48  ? 0.24197 0.20087 0.19685 0.08468  -0.00007 0.00550  75  MET A CA  
369  C CA  B MET A 48  ? 0.24241 0.20105 0.19708 0.08493  -0.00013 0.00548  75  MET A CA  
370  C C   A MET A 48  ? 0.26193 0.19502 0.20360 0.08817  -0.00298 0.00549  75  MET A C   
371  C C   B MET A 48  ? 0.26229 0.19526 0.20391 0.08807  -0.00297 0.00549  75  MET A C   
372  O O   A MET A 48  ? 0.27896 0.21254 0.21101 0.09646  -0.00141 0.00264  75  MET A O   
373  O O   B MET A 48  ? 0.27894 0.21241 0.21097 0.09602  -0.00133 0.00266  75  MET A O   
374  C CB  A MET A 48  ? 0.24041 0.21150 0.20364 0.07104  0.00363  0.00591  75  MET A CB  
375  C CB  B MET A 48  ? 0.24104 0.21291 0.20423 0.07161  0.00372  0.00576  75  MET A CB  
376  C CG  A MET A 48  ? 0.24566 0.23028 0.20601 0.07040  0.00960  0.00269  75  MET A CG  
377  C CG  B MET A 48  ? 0.28016 0.28015 0.25582 0.06906  0.00654  0.00447  75  MET A CG  
378  S SD  A MET A 48  ? 0.28231 0.30427 0.25478 0.07858  0.01509  -0.00254 75  MET A SD  
379  S SD  B MET A 48  ? 0.25821 0.28555 0.23789 0.08123  0.01030  -0.00149 75  MET A SD  
380  C CE  A MET A 48  ? 0.25639 0.29976 0.24455 0.06353  0.01771  -0.00180 75  MET A CE  
381  C CE  B MET A 48  ? 0.27013 0.29273 0.24062 0.07693  0.01767  -0.00326 75  MET A CE  
382  N N   . ALA A 49  ? 0.26111 0.17132 0.20294 0.08188  -0.00720 0.00800  76  ALA A N   
383  C CA  . ALA A 49  ? 0.26546 0.15011 0.19607 0.08461  -0.01208 0.00738  76  ALA A CA  
384  C C   . ALA A 49  ? 0.31408 0.18798 0.23225 0.09813  -0.01366 0.00631  76  ALA A C   
385  O O   . ALA A 49  ? 0.33406 0.20040 0.23970 0.10349  -0.01484 0.00401  76  ALA A O   
386  C CB  . ALA A 49  ? 0.31574 0.18146 0.25515 0.07485  -0.01687 0.00911  76  ALA A CB  
387  N N   . ALA A 50  ? 0.28288 0.15987 0.20447 0.09898  -0.01298 0.00740  77  ALA A N   
388  C CA  . ALA A 50  ? 0.30152 0.17343 0.21225 0.10585  -0.01419 0.00586  77  ALA A CA  
389  C C   . ALA A 50  ? 0.31683 0.20302 0.21958 0.12069  -0.01275 0.00254  77  ALA A C   
390  O O   . ALA A 50  ? 0.34452 0.22319 0.23515 0.12677  -0.01400 0.00029  77  ALA A O   
391  C CB  . ALA A 50  ? 0.32034 0.18941 0.23204 0.10418  -0.01360 0.00774  77  ALA A CB  
392  N N   . ALA A 51  ? 0.30284 0.21229 0.21460 0.12688  -0.00964 0.00157  78  ALA A N   
393  C CA  . ALA A 51  ? 0.28976 0.22098 0.20198 0.13847  -0.00660 -0.00326 78  ALA A CA  
394  C C   . ALA A 51  ? 0.31790 0.24528 0.22239 0.13819  -0.00249 -0.00557 78  ALA A C   
395  O O   . ALA A 51  ? 0.32236 0.25355 0.21945 0.15062  -0.00003 -0.00973 78  ALA A O   
396  C CB  . ALA A 51  ? 0.29749 0.26348 0.22876 0.13462  -0.00324 -0.00501 78  ALA A CB  
397  N N   . ALA A 52  ? 0.27811 0.19617 0.18255 0.12473  -0.00182 -0.00329 79  ALA A N   
398  C CA  . ALA A 52  ? 0.29179 0.19988 0.18265 0.12458  0.00135  -0.00535 79  ALA A CA  
399  C C   . ALA A 52  ? 0.36644 0.24452 0.23701 0.13474  -0.00399 -0.00606 79  ALA A C   
400  O O   . ALA A 52  ? 0.36943 0.24168 0.22493 0.14252  -0.00036 -0.00939 79  ALA A O   
401  C CB  . ALA A 52  ? 0.30179 0.20003 0.19306 0.10913  0.00017  -0.00276 79  ALA A CB  
402  N N   . VAL A 53  ? 0.33311 0.19480 0.20457 0.12861  -0.01153 -0.00318 80  VAL A N   
403  C CA  . VAL A 53  ? 0.34451 0.18734 0.20216 0.12843  -0.01615 -0.00413 80  VAL A CA  
404  C C   . VAL A 53  ? 0.40303 0.25336 0.25340 0.14143  -0.01427 -0.00654 80  VAL A C   
405  O O   . VAL A 53  ? 0.37183 0.21112 0.20582 0.14810  -0.01476 -0.00879 80  VAL A O   
406  C CB  . VAL A 53  ? 0.38402 0.21565 0.25126 0.11461  -0.02189 -0.00163 80  VAL A CB  
407  C CG1 . VAL A 53  ? 0.45561 0.27090 0.31091 0.11527  -0.02595 -0.00290 80  VAL A CG1 
408  C CG2 . VAL A 53  ? 0.38848 0.21457 0.26475 0.10254  -0.02489 -0.00042 80  VAL A CG2 
409  N N   . LEU A 54  ? 0.35943 0.22848 0.22108 0.14565  -0.01278 -0.00642 81  LEU A N   
410  C CA  . LEU A 54  ? 0.40080 0.27918 0.25736 0.15850  -0.01257 -0.00944 81  LEU A CA  
411  C C   . LEU A 54  ? 0.36705 0.25931 0.22127 0.17027  -0.00626 -0.01407 81  LEU A C   
412  O O   . LEU A 54  ? 0.39335 0.28124 0.23594 0.17962  -0.00644 -0.01677 81  LEU A O   
413  C CB  . LEU A 54  ? 0.34741 0.24353 0.21651 0.16057  -0.01373 -0.00915 81  LEU A CB  
414  C CG  . LEU A 54  ? 0.37379 0.25344 0.23912 0.15283  -0.01817 -0.00572 81  LEU A CG  
415  C CD1 . LEU A 54  ? 0.37201 0.26726 0.24625 0.15577  -0.01936 -0.00562 81  LEU A CD1 
416  C CD2 . LEU A 54  ? 0.44156 0.30160 0.28830 0.15721  -0.02164 -0.00676 81  LEU A CD2 
417  N N   . LYS A 55  ? 0.34922 0.25744 0.21379 0.16942  0.00087  -0.01556 82  LYS A N   
418  C CA  . LYS A 55  ? 0.36350 0.28662 0.22711 0.17808  0.01101  -0.02128 82  LYS A CA  
419  C C   . LYS A 55  ? 0.42005 0.31375 0.25793 0.17968  0.01148  -0.02152 82  LYS A C   
420  O O   . LYS A 55  ? 0.43114 0.32843 0.26161 0.18902  0.01680  -0.02559 82  LYS A O   
421  C CB  . LYS A 55  ? 0.35946 0.30592 0.23838 0.16844  0.02023  -0.02244 82  LYS A CB  
422  C CG  . LYS A 55  ? 0.38778 0.34658 0.26366 0.16937  0.03374  -0.02773 82  LYS A CG  
423  C CD  . LYS A 55  ? 0.47310 0.45721 0.35946 0.18562  0.04032  -0.03526 82  LYS A CD  
424  C CE  . LYS A 55  ? 0.41964 0.44524 0.33902 0.18519  0.04045  -0.03803 82  LYS A CE  
425  N NZ  . LYS A 55  ? 0.42711 0.47856 0.36267 0.19491  0.04362  -0.04488 82  LYS A NZ  
426  N N   . GLN A 56  ? 0.38371 0.24799 0.20867 0.16990  0.00476  -0.01732 83  GLN A N   
427  C CA  . GLN A 56  ? 0.44604 0.28077 0.24536 0.17030  0.00246  -0.01753 83  GLN A CA  
428  C C   . GLN A 56  ? 0.54219 0.36812 0.33098 0.17681  -0.00280 -0.01783 83  GLN A C   
429  O O   . GLN A 56  ? 0.50258 0.31337 0.27104 0.18326  -0.00118 -0.01974 83  GLN A O   
430  C CB  . GLN A 56  ? 0.44197 0.25192 0.23562 0.15586  -0.00659 -0.01368 83  GLN A CB  
431  C CG  . GLN A 56  ? 0.47551 0.28183 0.26883 0.14970  -0.00299 -0.01348 83  GLN A CG  
432  C CD  . GLN A 56  ? 0.63426 0.41874 0.42515 0.13451  -0.01491 -0.01024 83  GLN A CD  
433  O OE1 . GLN A 56  ? 0.56166 0.34763 0.36657 0.12605  -0.02281 -0.00844 83  GLN A OE1 
434  N NE2 . GLN A 56  ? 0.66228 0.42799 0.43666 0.13020  -0.01537 -0.01064 83  GLN A NE2 
435  N N   . SER A 57  ? 0.48537 0.31745 0.28453 0.17495  -0.00859 -0.01611 84  SER A N   
436  C CA  . SER A 57  ? 0.46147 0.28263 0.24854 0.18032  -0.01347 -0.01670 84  SER A CA  
437  C C   . SER A 57  ? 0.51349 0.34991 0.29886 0.19642  -0.00861 -0.02080 84  SER A C   
438  O O   . SER A 57  ? 0.54449 0.36922 0.31569 0.20313  -0.01236 -0.02178 84  SER A O   
439  C CB  . SER A 57  ? 0.43080 0.25213 0.22748 0.17314  -0.01908 -0.01419 84  SER A CB  
440  O OG  . SER A 57  ? 0.46816 0.31259 0.27824 0.17997  -0.01730 -0.01520 84  SER A OG  
441  N N   . GLU A 58  ? 0.44948 0.31333 0.25104 0.20210  0.00007  -0.02404 85  GLU A N   
442  C CA  . GLU A 58  ? 0.47820 0.36067 0.28421 0.21597  0.00552  -0.02946 85  GLU A CA  
443  C C   . GLU A 58  ? 0.54500 0.40979 0.32967 0.22189  0.01075  -0.03152 85  GLU A C   
444  O O   . GLU A 58  ? 0.56767 0.43608 0.34862 0.23330  0.01209  -0.03506 85  GLU A O   
445  C CB  . GLU A 58  ? 0.42402 0.34533 0.25823 0.21762  0.01495  -0.03407 85  GLU A CB  
446  C CG  . GLU A 58  ? 0.46016 0.40034 0.31496 0.21369  0.00879  -0.03253 85  GLU A CG  
447  C CD  . GLU A 58  ? 0.39956 0.37895 0.28344 0.21264  0.01728  -0.03713 85  GLU A CD  
448  O OE1 . GLU A 58  ? 0.52176 0.51963 0.41426 0.21625  0.02882  -0.04302 85  GLU A OE1 
449  O OE2 . GLU A 58  ? 0.48660 0.47783 0.38465 0.20677  0.01293  -0.03500 85  GLU A OE2 
450  N N   . THR A 59  ? 0.58549 0.51577 0.35628 0.24585  0.07970  -0.03142 86  THR A N   
451  C CA  . THR A 59  ? 0.61529 0.51570 0.35660 0.25918  0.08798  -0.03237 86  THR A CA  
452  C C   . THR A 59  ? 0.64651 0.48067 0.33991 0.25662  0.07512  -0.02981 86  THR A C   
453  O O   . THR A 59  ? 0.75947 0.55984 0.41946 0.27633  0.07458  -0.03481 86  THR A O   
454  C CB  . THR A 59  ? 0.63579 0.55639 0.39436 0.24524  0.11019  -0.03090 86  THR A CB  
455  O OG1 . THR A 59  ? 0.64688 0.62717 0.45515 0.24164  0.12749  -0.03756 86  THR A OG1 
456  C CG2 . THR A 59  ? 0.66876 0.56513 0.39473 0.26434  0.12001  -0.03250 86  THR A CG2 
457  N N   . GLN A 60  ? 0.62991 0.44594 0.32101 0.23129  0.06668  -0.02457 87  GLN A N   
458  C CA  . GLN A 60  ? 0.65788 0.41829 0.31231 0.22244  0.05561  -0.02672 87  GLN A CA  
459  C C   . GLN A 60  ? 0.71392 0.44198 0.35612 0.22610  0.04559  -0.02434 87  GLN A C   
460  O O   . GLN A 60  ? 0.65821 0.38252 0.30999 0.20731  0.03925  -0.01809 87  GLN A O   
461  C CB  . GLN A 60  ? 0.63138 0.39575 0.29208 0.19506  0.05424  -0.02272 87  GLN A CB  
462  C CG  . GLN A 60  ? 0.71851 0.51045 0.38386 0.19759  0.06832  -0.02111 87  GLN A CG  
463  C CD  . GLN A 60  ? 0.74205 0.54225 0.41259 0.17660  0.06898  -0.01356 87  GLN A CD  
464  O OE1 . GLN A 60  ? 0.88155 0.66018 0.53357 0.16544  0.05596  -0.01811 87  GLN A OE1 
465  N NE2 . GLN A 60  ? 0.73700 0.56882 0.43377 0.17099  0.08656  -0.00337 87  GLN A NE2 
466  N N   . LYS A 61  ? 0.73266 0.43131 0.34835 0.25314  0.04697  -0.02802 88  LYS A N   
467  C CA  . LYS A 61  ? 0.77034 0.44462 0.37240 0.26897  0.04302  -0.02177 88  LYS A CA  
468  C C   . LYS A 61  ? 0.76739 0.38483 0.34830 0.24753  0.03960  -0.01953 88  LYS A C   
469  O O   . LYS A 61  ? 0.80924 0.41483 0.38605 0.25323  0.03702  -0.01021 88  LYS A O   
470  C CB  . LYS A 61  ? 0.84185 0.48800 0.41237 0.30672  0.04993  -0.02447 88  LYS A CB  
471  C CG  . LYS A 61  ? 0.88226 0.59099 0.47849 0.33006  0.05425  -0.02689 88  LYS A CG  
472  C CD  . LYS A 61  ? 0.98212 0.75804 0.61704 0.33754  0.04810  -0.02255 88  LYS A CD  
473  C CE  . LYS A 61  ? 1.02839 0.85190 0.67490 0.37587  0.05241  -0.02665 88  LYS A CE  
474  N NZ  . LYS A 61  ? 1.05390 0.90361 0.71844 0.37172  0.06454  -0.03476 88  LYS A NZ  
475  N N   . GLN A 62  ? 0.81012 0.39612 0.37813 0.22372  0.04025  -0.02938 89  GLN A N   
476  C CA  . GLN A 62  ? 0.91116 0.44684 0.46463 0.19916  0.03980  -0.03194 89  GLN A CA  
477  C C   . GLN A 62  ? 0.87784 0.44700 0.46214 0.16712  0.03186  -0.02739 89  GLN A C   
478  O O   . GLN A 62  ? 0.79954 0.33626 0.37818 0.14290  0.03149  -0.03168 89  GLN A O   
479  C CB  . GLN A 62  ? 1.07228 0.55801 0.59594 0.18952  0.04563  -0.05190 89  GLN A CB  
480  C CG  . GLN A 62  ? 1.26733 0.71842 0.76049 0.21757  0.05630  -0.05616 89  GLN A CG  
481  C CD  . GLN A 62  ? 1.40898 0.83403 0.88994 0.23523  0.06374  -0.03919 89  GLN A CD  
482  O OE1 . GLN A 62  ? 1.43697 0.83947 0.91795 0.22075  0.06574  -0.03164 89  GLN A OE1 
483  N NE2 . GLN A 62  ? 1.50659 0.93894 0.97553 0.26826  0.06873  -0.03233 89  GLN A NE2 
484  N N   . LEU A 63  ? 0.73877 0.36992 0.35572 0.16585  0.02893  -0.01985 90  LEU A N   
485  C CA  . LEU A 63  ? 0.66360 0.32210 0.30435 0.13796  0.02549  -0.01565 90  LEU A CA  
486  C C   . LEU A 63  ? 0.68292 0.32035 0.32791 0.12053  0.02214  -0.00754 90  LEU A C   
487  O O   . LEU A 63  ? 0.63025 0.26213 0.28064 0.09543  0.01966  -0.00897 90  LEU A O   
488  C CB  . LEU A 63  ? 0.60081 0.31880 0.27320 0.14076  0.03056  -0.00806 90  LEU A CB  
489  C CG  . LEU A 63  ? 0.61252 0.35574 0.30612 0.11673  0.03254  -0.00055 90  LEU A CG  
490  C CD1 . LEU A 63  ? 0.58086 0.31656 0.25847 0.10827  0.03003  -0.00759 90  LEU A CD1 
491  C CD2 . LEU A 63  ? 0.58025 0.37093 0.30207 0.12066  0.04559  0.00508  90  LEU A CD2 
492  N N   . LEU A 64  ? 0.65002 0.27918 0.29167 0.13605  0.02224  0.00090  91  LEU A N   
493  C CA  . LEU A 64  ? 0.64396 0.25588 0.28814 0.12176  0.02049  0.01056  91  LEU A CA  
494  C C   . LEU A 64  ? 0.74313 0.28954 0.36201 0.10656  0.02528  0.00516  91  LEU A C   
495  O O   . LEU A 64  ? 0.69398 0.22547 0.31821 0.08660  0.02602  0.01108  91  LEU A O   
496  C CB  . LEU A 64  ? 0.70703 0.32777 0.34746 0.14702  0.01885  0.01982  91  LEU A CB  
497  C CG  . LEU A 64  ? 0.64950 0.34447 0.32560 0.15311  0.01501  0.02043  91  LEU A CG  
498  C CD1 . LEU A 64  ? 0.69032 0.40034 0.36266 0.17505  0.00968  0.02618  91  LEU A CD1 
499  C CD2 . LEU A 64  ? 0.65664 0.38481 0.36529 0.12139  0.01668  0.02225  91  LEU A CD2 
500  N N   . ASN A 65  ? 0.73463 0.24082 0.32754 0.11300  0.03121  -0.00833 92  ASN A N   
501  C CA  . ASN A 65  ? 0.78160 0.22451 0.35433 0.09356  0.04072  -0.01905 92  ASN A CA  
502  C C   . ASN A 65  ? 0.76550 0.22756 0.35447 0.06209  0.03565  -0.03735 92  ASN A C   
503  O O   . ASN A 65  ? 0.81935 0.23891 0.39891 0.04033  0.04379  -0.05369 92  ASN A O   
504  C CB  . ASN A 65  ? 0.84411 0.24432 0.38739 0.11164  0.05334  -0.02499 92  ASN A CB  
505  C CG  . ASN A 65  ? 1.01368 0.41098 0.54321 0.14298  0.05809  -0.00604 92  ASN A CG  
506  O OD1 . ASN A 65  ? 1.24305 0.64666 0.75787 0.17516  0.05851  -0.00384 92  ASN A OD1 
507  N ND2 . ASN A 65  ? 0.98289 0.37768 0.51725 0.13594  0.06133  0.00666  92  ASN A ND2 
508  N N   . GLN A 66  ? 0.72896 0.25493 0.34174 0.06002  0.02463  -0.03581 93  GLN A N   
509  C CA  . GLN A 66  ? 0.71929 0.27264 0.34189 0.03986  0.01826  -0.05276 93  GLN A CA  
510  C C   . GLN A 66  ? 0.74787 0.30499 0.39003 0.01022  0.01675  -0.05195 93  GLN A C   
511  O O   . GLN A 66  ? 0.68084 0.25599 0.34031 0.00785  0.01587  -0.03167 93  GLN A O   
512  C CB  . GLN A 66  ? 0.72553 0.34017 0.36103 0.05340  0.01210  -0.04599 93  GLN A CB  
513  C CG  . GLN A 66  ? 0.93712 0.58910 0.57613 0.04350  0.00476  -0.06047 93  GLN A CG  
514  C CD  . GLN A 66  ? 0.95269 0.65758 0.60114 0.05970  0.00551  -0.04591 93  GLN A CD  
515  O OE1 . GLN A 66  ? 0.94207 0.65459 0.58008 0.08202  0.01025  -0.04458 93  GLN A OE1 
516  N NE2 . GLN A 66  ? 0.87289 0.61034 0.53988 0.04948  0.00487  -0.03397 93  GLN A NE2 
517  N N   . PRO A 67  ? 0.71451 0.25734 0.35639 -0.01375 0.01760  -0.07578 94  PRO A N   
518  C CA  . PRO A 67  ? 0.69825 0.25039 0.36303 -0.04257 0.01725  -0.07711 94  PRO A CA  
519  C C   . PRO A 67  ? 0.64723 0.27296 0.33499 -0.04409 0.00436  -0.07212 94  PRO A C   
520  O O   . PRO A 67  ? 0.64397 0.30943 0.32708 -0.03237 -0.00396 -0.08253 94  PRO A O   
521  C CB  . PRO A 67  ? 0.77112 0.29009 0.43078 -0.06792 0.02455  -0.11148 94  PRO A CB  
522  C CG  . PRO A 67  ? 0.91028 0.39319 0.53897 -0.05068 0.03030  -0.12597 94  PRO A CG  
523  C CD  . PRO A 67  ? 0.76619 0.28546 0.38860 -0.01712 0.02050  -0.10614 94  PRO A CD  
524  N N   . VAL A 68  ? 0.61333 0.25377 0.32167 -0.05570 0.00504  -0.05501 95  VAL A N   
525  C CA  . VAL A 68  ? 0.57041 0.27271 0.29765 -0.05498 -0.00209 -0.04551 95  VAL A CA  
526  C C   . VAL A 68  ? 0.56720 0.27772 0.31614 -0.08264 -0.00205 -0.05300 95  VAL A C   
527  O O   . VAL A 68  ? 0.59404 0.26479 0.34805 -0.09689 0.00713  -0.04378 95  VAL A O   
528  C CB  . VAL A 68  ? 0.59712 0.31050 0.32963 -0.03998 0.00308  -0.01435 95  VAL A CB  
529  C CG1 . VAL A 68  ? 0.56488 0.33007 0.31309 -0.03925 0.00278  -0.00155 95  VAL A CG1 
530  C CG2 . VAL A 68  ? 0.63758 0.35041 0.35503 -0.01453 0.00493  -0.01044 95  VAL A CG2 
531  N N   A GLU A 69  ? 0.56294 0.32935 0.32408 -0.08715 -0.01176 -0.06875 96  GLU A N   
532  N N   B GLU A 69  ? 0.56383 0.32907 0.32458 -0.08767 -0.01182 -0.07013 96  GLU A N   
533  C CA  A GLU A 69  ? 0.56076 0.34779 0.34760 -0.11379 -0.01280 -0.08241 96  GLU A CA  
534  C CA  B GLU A 69  ? 0.55919 0.34571 0.34614 -0.11340 -0.01249 -0.08079 96  GLU A CA  
535  C C   A GLU A 69  ? 0.53160 0.33561 0.33455 -0.11343 -0.00832 -0.05212 96  GLU A C   
536  C C   B GLU A 69  ? 0.54394 0.33796 0.34462 -0.11273 -0.00654 -0.04854 96  GLU A C   
537  O O   A GLU A 69  ? 0.49071 0.32566 0.28876 -0.09078 -0.00901 -0.02966 96  GLU A O   
538  O O   B GLU A 69  ? 0.51353 0.32571 0.30761 -0.09071 -0.00519 -0.02322 96  GLU A O   
539  C CB  A GLU A 69  ? 0.57017 0.42545 0.36411 -0.11300 -0.02758 -0.11246 96  GLU A CB  
540  C CB  B GLU A 69  ? 0.57172 0.43313 0.36873 -0.11132 -0.02716 -0.10526 96  GLU A CB  
541  C CG  A GLU A 69  ? 0.58569 0.46562 0.40954 -0.14586 -0.02948 -0.14382 96  GLU A CG  
542  C CG  B GLU A 69  ? 0.59899 0.46704 0.38185 -0.11023 -0.03521 -0.14049 96  GLU A CG  
543  C CD  A GLU A 69  ? 0.61236 0.57225 0.44216 -0.14085 -0.04757 -0.17807 96  GLU A CD  
544  C CD  B GLU A 69  ? 0.59661 0.55177 0.38387 -0.09746 -0.05253 -0.15978 96  GLU A CD  
545  O OE1 A GLU A 69  ? 0.62381 0.61453 0.42931 -0.10817 -0.05737 -0.17180 96  GLU A OE1 
546  O OE1 B GLU A 69  ? 0.60112 0.60076 0.41588 -0.11889 -0.05898 -0.18500 96  GLU A OE1 
547  O OE2 A GLU A 69  ? 0.61331 0.60760 0.47198 -0.16873 -0.05098 -0.21245 96  GLU A OE2 
548  O OE2 B GLU A 69  ? 0.59216 0.57426 0.35529 -0.06392 -0.05844 -0.14910 96  GLU A OE2 
549  N N   . ILE A 70  ? 0.52245 0.30104 0.34272 -0.13852 0.00021  -0.05134 97  ILE A N   
550  C CA  . ILE A 70  ? 0.48829 0.28100 0.32417 -0.14099 0.00574  -0.02536 97  ILE A CA  
551  C C   . ILE A 70  ? 0.54316 0.39204 0.40728 -0.15666 0.00022  -0.04357 97  ILE A C   
552  O O   . ILE A 70  ? 0.53667 0.37255 0.41799 -0.18512 0.00416  -0.06923 97  ILE A O   
553  C CB  . ILE A 70  ? 0.53035 0.25758 0.36337 -0.15407 0.02012  -0.00913 97  ILE A CB  
554  C CG1 . ILE A 70  ? 0.55129 0.23621 0.35914 -0.13424 0.02268  0.00157  97  ILE A CG1 
555  C CG2 . ILE A 70  ? 0.55069 0.30043 0.39952 -0.15025 0.02512  0.01706  97  ILE A CG2 
556  C CD1 . ILE A 70  ? 0.56237 0.26846 0.36116 -0.11201 0.02020  0.02349  97  ILE A CD1 
557  N N   . LYS A 71  ? 0.47051 0.38287 0.33917 -0.13700 -0.00650 -0.03208 98  LYS A N   
558  C CA  . LYS A 71  ? 0.46438 0.44527 0.35951 -0.14421 -0.01417 -0.04888 98  LYS A CA  
559  C C   . LYS A 71  ? 0.42888 0.41598 0.33908 -0.14600 -0.00345 -0.02062 98  LYS A C   
560  O O   . LYS A 71  ? 0.45413 0.40625 0.34915 -0.13388 0.00783  0.01277  98  LYS A O   
561  C CB  . LYS A 71  ? 0.47088 0.52601 0.35450 -0.11295 -0.02923 -0.05704 98  LYS A CB  
562  C CG  . LYS A 71  ? 0.59533 0.65550 0.46604 -0.11286 -0.04165 -0.09204 98  LYS A CG  
563  C CD  . LYS A 71  ? 0.81426 0.94259 0.66372 -0.07438 -0.05516 -0.09507 98  LYS A CD  
564  C CE  . LYS A 71  ? 0.93698 1.05053 0.75759 -0.03780 -0.04302 -0.05068 98  LYS A CE  
565  N NZ  . LYS A 71  ? 0.79627 0.83315 0.60027 -0.03998 -0.03048 -0.03313 98  LYS A NZ  
566  N N   . PRO A 72  ? 0.42807 0.46181 0.36991 -0.16193 -0.00549 -0.03535 99  PRO A N   
567  C CA  . PRO A 72  ? 0.44048 0.47872 0.39529 -0.16189 0.00649  -0.00711 99  PRO A CA  
568  C C   . PRO A 72  ? 0.51043 0.56866 0.44298 -0.12462 0.01124  0.02859  99  PRO A C   
569  O O   . PRO A 72  ? 0.53667 0.56127 0.46493 -0.12343 0.02726  0.05929  99  PRO A O   
570  C CB  . PRO A 72  ? 0.41687 0.52536 0.41090 -0.17819 -0.00024 -0.03514 99  PRO A CB  
571  C CG  . PRO A 72  ? 0.46766 0.57141 0.47452 -0.20580 -0.00745 -0.08048 99  PRO A CG  
572  C CD  . PRO A 72  ? 0.45182 0.53286 0.42225 -0.18490 -0.01613 -0.08133 99  PRO A CD  
573  N N   . ALA A 73  ? 0.40910 0.51624 0.32409 -0.09368 0.00090  0.02471  100 ALA A N   
574  C CA  . ALA A 73  ? 0.50357 0.62528 0.39224 -0.05485 0.01158  0.05796  100 ALA A CA  
575  C C   . ALA A 73  ? 0.49967 0.55262 0.36365 -0.05007 0.02713  0.08199  100 ALA A C   
576  O O   . ALA A 73  ? 0.56429 0.61226 0.40970 -0.02599 0.04500  0.11114  100 ALA A O   
577  C CB  . ALA A 73  ? 0.49055 0.68116 0.36217 -0.01999 -0.00201 0.04568  100 ALA A CB  
578  N N   . ASP A 74  ? 0.46217 0.46406 0.32544 -0.07119 0.02297  0.06895  101 ASP A N   
579  C CA  . ASP A 74  ? 0.49120 0.43834 0.33660 -0.06759 0.03531  0.08682  101 ASP A CA  
580  C C   . ASP A 74  ? 0.55022 0.46044 0.41191 -0.07830 0.04923  0.10353  101 ASP A C   
581  O O   . ASP A 74  ? 0.48933 0.40294 0.37901 -0.05532 0.05393  0.10730  101 ASP A O   
582  C CB  . ASP A 74  ? 0.50244 0.41451 0.34184 -0.07886 0.02493  0.06576  101 ASP A CB  
583  C CG  . ASP A 74  ? 0.58222 0.52757 0.40827 -0.06128 0.01194  0.04565  101 ASP A CG  
584  O OD1 . ASP A 74  ? 0.56201 0.54213 0.37251 -0.03208 0.01596  0.05715  101 ASP A OD1 
585  O OD2 . ASP A 74  ? 0.52231 0.45469 0.35003 -0.07545 0.00053  0.01852  101 ASP A OD2 
586  N N   . LEU A 75  ? 0.39273 0.37243 0.44296 -0.13369 0.03601  -0.05217 102 LEU A N   
587  C CA  . LEU A 75  ? 0.39239 0.37527 0.44290 -0.13513 0.04709  -0.04935 102 LEU A CA  
588  C C   . LEU A 75  ? 0.42938 0.44592 0.50727 -0.12080 0.04659  -0.05063 102 LEU A C   
589  O O   . LEU A 75  ? 0.41080 0.45994 0.51553 -0.11892 0.04132  -0.05695 102 LEU A O   
590  C CB  . LEU A 75  ? 0.41000 0.40001 0.46057 -0.15394 0.05474  -0.05177 102 LEU A CB  
591  C CG  . LEU A 75  ? 0.42267 0.37534 0.44022 -0.16471 0.05362  -0.04892 102 LEU A CG  
592  C CD1 . LEU A 75  ? 0.48935 0.45335 0.50813 -0.18145 0.06015  -0.05100 102 LEU A CD1 
593  C CD2 . LEU A 75  ? 0.43550 0.34483 0.41797 -0.15774 0.05622  -0.04158 102 LEU A CD2 
594  N N   . VAL A 76  ? 0.36018 0.36693 0.42924 -0.10999 0.05093  -0.04477 103 VAL A N   
595  C CA  . VAL A 76  ? 0.31843 0.35183 0.40838 -0.09735 0.05080  -0.04576 103 VAL A CA  
596  C C   . VAL A 76  ? 0.37286 0.41164 0.46331 -0.10435 0.06329  -0.04559 103 VAL A C   
597  O O   . VAL A 76  ? 0.38631 0.43137 0.47912 -0.12191 0.07155  -0.04941 103 VAL A O   
598  C CB  . VAL A 76  ? 0.35402 0.37542 0.43539 -0.07828 0.04362  -0.03973 103 VAL A CB  
599  C CG1 . VAL A 76  ? 0.36644 0.39168 0.45316 -0.07160 0.03197  -0.04196 103 VAL A CG1 
600  C CG2 . VAL A 76  ? 0.36041 0.34683 0.41261 -0.07575 0.04601  -0.03182 103 VAL A CG2 
601  N N   . ASN A 77  ? 0.32554 0.36215 0.41295 -0.09197 0.06504  -0.04143 104 ASN A N   
602  C CA  . ASN A 77  ? 0.39873 0.44513 0.48954 -0.09637 0.07636  -0.04255 104 ASN A CA  
603  C C   . ASN A 77  ? 0.44548 0.46022 0.50786 -0.10632 0.08552  -0.03704 104 ASN A C   
604  O O   . ASN A 77  ? 0.47725 0.49822 0.53959 -0.11527 0.09655  -0.03889 104 ASN A O   
605  C CB  . ASN A 77  ? 0.35358 0.40939 0.45094 -0.07923 0.07389  -0.04100 104 ASN A CB  
606  C CG  . ASN A 77  ? 0.34454 0.37257 0.42060 -0.06806 0.06815  -0.03229 104 ASN A CG  
607  O OD1 . ASN A 77  ? 0.35118 0.36171 0.41567 -0.06688 0.06204  -0.02882 104 ASN A OD1 
608  N ND2 . ASN A 77  ? 0.38454 0.40923 0.45502 -0.05978 0.07008  -0.02904 104 ASN A ND2 
609  N N   . TYR A 78  ? 0.36494 0.34552 0.40160 -0.10317 0.08087  -0.03043 105 TYR A N   
610  C CA  . TYR A 78  ? 0.37525 0.32141 0.38095 -0.10926 0.08737  -0.02480 105 TYR A CA  
611  C C   . TYR A 78  ? 0.37451 0.28833 0.35614 -0.11113 0.08169  -0.02163 105 TYR A C   
612  O O   . TYR A 78  ? 0.41179 0.31416 0.38611 -0.09629 0.07296  -0.01742 105 TYR A O   
613  C CB  . TYR A 78  ? 0.35859 0.29515 0.35465 -0.09540 0.08651  -0.01881 105 TYR A CB  
614  C CG  . TYR A 78  ? 0.42781 0.32959 0.39163 -0.10155 0.09276  -0.01365 105 TYR A CG  
615  C CD1 . TYR A 78  ? 0.49049 0.39316 0.44787 -0.11287 0.10131  -0.01634 105 TYR A CD1 
616  C CD2 . TYR A 78  ? 0.42004 0.29184 0.35950 -0.09122 0.08613  -0.00676 105 TYR A CD2 
617  C CE1 . TYR A 78  ? 0.48807 0.35992 0.41399 -0.11473 0.10324  -0.01242 105 TYR A CE1 
618  C CE2 . TYR A 78  ? 0.53461 0.37596 0.44340 -0.09298 0.08830  -0.00278 105 TYR A CE2 
619  C CZ  . TYR A 78  ? 0.66556 0.50689 0.56728 -0.10436 0.09621  -0.00583 105 TYR A CZ  
620  O OH  . TYR A 78  ? 0.64242 0.45432 0.51289 -0.10492 0.09685  -0.00288 105 TYR A OH  
621  N N   . ASN A 79  ? 0.36431 0.26588 0.33273 -0.12600 0.08481  -0.02368 106 ASN A N   
622  C CA  . ASN A 79  ? 0.41983 0.29147 0.36498 -0.12757 0.07854  -0.02202 106 ASN A CA  
623  C C   . ASN A 79  ? 0.38381 0.22676 0.29718 -0.13624 0.08210  -0.01995 106 ASN A C   
624  O O   . ASN A 79  ? 0.45577 0.29428 0.36219 -0.14874 0.08209  -0.02289 106 ASN A O   
625  C CB  . ASN A 79  ? 0.46973 0.35968 0.43302 -0.13516 0.07385  -0.02810 106 ASN A CB  
626  C CG  . ASN A 79  ? 0.41109 0.34470 0.41331 -0.13346 0.07377  -0.03373 106 ASN A CG  
627  O OD1 . ASN A 79  ? 0.42429 0.36906 0.43830 -0.11617 0.06678  -0.03231 106 ASN A OD1 
628  N ND2 . ASN A 79  ? 0.45397 0.41636 0.47474 -0.14370 0.07780  -0.03912 106 ASN A ND2 
629  N N   . PRO A 80  ? 0.38788 0.20944 0.27959 -0.12981 0.08440  -0.01498 107 PRO A N   
630  C CA  . PRO A 80  ? 0.42558 0.22199 0.28739 -0.13907 0.08859  -0.01416 107 PRO A CA  
631  C C   . PRO A 80  ? 0.51378 0.27611 0.34505 -0.14089 0.08297  -0.01296 107 PRO A C   
632  O O   . PRO A 80  ? 0.55743 0.30540 0.36912 -0.15459 0.08662  -0.01461 107 PRO A O   
633  C CB  . PRO A 80  ? 0.47424 0.25614 0.32110 -0.12829 0.08979  -0.00928 107 PRO A CB  
634  C CG  . PRO A 80  ? 0.52187 0.30843 0.38010 -0.11145 0.08306  -0.00577 107 PRO A CG  
635  C CD  . PRO A 80  ? 0.40701 0.22693 0.30005 -0.11446 0.08280  -0.01023 107 PRO A CD  
636  N N   . ILE A 81  ? 0.45921 0.20760 0.28434 -0.12764 0.07441  -0.01052 108 ILE A N   
637  C CA  . ILE A 81  ? 0.48965 0.20507 0.28450 -0.12702 0.06854  -0.00980 108 ILE A CA  
638  C C   . ILE A 81  ? 0.47168 0.19875 0.28052 -0.13522 0.06527  -0.01417 108 ILE A C   
639  O O   . ILE A 81  ? 0.49471 0.20480 0.28430 -0.14663 0.06464  -0.01584 108 ILE A O   
640  C CB  . ILE A 81  ? 0.48545 0.17598 0.26052 -0.10548 0.06070  -0.00502 108 ILE A CB  
641  C CG1 . ILE A 81  ? 0.53039 0.21177 0.29303 -0.09707 0.06237  -0.00094 108 ILE A CG1 
642  C CG2 . ILE A 81  ? 0.56762 0.22305 0.30831 -0.10379 0.05496  -0.00489 108 ILE A CG2 
643  C CD1 . ILE A 81  ? 0.56174 0.22077 0.29528 -0.10856 0.06717  -0.00114 108 ILE A CD1 
644  N N   . ALA A 82  ? 0.42728 0.18203 0.26771 -0.12995 0.06268  -0.01623 109 ALA A N   
645  C CA  . ALA A 82  ? 0.44673 0.21297 0.30064 -0.13655 0.05800  -0.02093 109 ALA A CA  
646  C C   . ALA A 82  ? 0.45779 0.24186 0.32180 -0.15757 0.06250  -0.02562 109 ALA A C   
647  O O   . ALA A 82  ? 0.47463 0.25091 0.33091 -0.16651 0.05836  -0.02820 109 ALA A O   
648  C CB  . ALA A 82  ? 0.40095 0.19668 0.28799 -0.12823 0.05502  -0.02321 109 ALA A CB  
649  N N   A GLU A 83  ? 0.48241 0.29031 0.36261 -0.16513 0.07096  -0.02686 110 GLU A N   
650  N N   B GLU A 83  ? 0.48267 0.29030 0.36256 -0.16535 0.07094  -0.02688 110 GLU A N   
651  C CA  A GLU A 83  ? 0.47230 0.30122 0.36385 -0.18417 0.07644  -0.03160 110 GLU A CA  
652  C CA  B GLU A 83  ? 0.47277 0.30181 0.36474 -0.18441 0.07581  -0.03182 110 GLU A CA  
653  C C   A GLU A 83  ? 0.51572 0.31066 0.37125 -0.19677 0.07654  -0.03076 110 GLU A C   
654  C C   B GLU A 83  ? 0.51626 0.31129 0.37162 -0.19721 0.07677  -0.03081 110 GLU A C   
655  O O   A GLU A 83  ? 0.56575 0.37205 0.42718 -0.21269 0.07677  -0.03485 110 GLU A O   
656  O O   B GLU A 83  ? 0.56328 0.37025 0.42433 -0.21387 0.07792  -0.03489 110 GLU A O   
657  C CB  A GLU A 83  ? 0.50472 0.35571 0.41001 -0.18687 0.08645  -0.03225 110 GLU A CB  
658  C CB  B GLU A 83  ? 0.50642 0.36479 0.41887 -0.18777 0.08542  -0.03346 110 GLU A CB  
659  C CG  A GLU A 83  ? 0.58325 0.44705 0.48973 -0.20615 0.09443  -0.03620 110 GLU A CG  
660  C CG  B GLU A 83  ? 0.57762 0.48483 0.53479 -0.18537 0.08501  -0.03871 110 GLU A CG  
661  C CD  A GLU A 83  ? 0.67228 0.58435 0.61938 -0.21359 0.09472  -0.04302 110 GLU A CD  
662  C CD  B GLU A 83  ? 0.57301 0.50277 0.54676 -0.17976 0.09284  -0.03895 110 GLU A CD  
663  O OE1 A GLU A 83  ? 0.55424 0.49436 0.53135 -0.20207 0.09079  -0.04490 110 GLU A OE1 
664  O OE1 B GLU A 83  ? 0.57508 0.49008 0.52978 -0.18462 0.10059  -0.03689 110 GLU A OE1 
665  O OE2 A GLU A 83  ? 0.64690 0.56896 0.59507 -0.23076 0.09850  -0.04670 110 GLU A OE2 
666  O OE2 B GLU A 83  ? 0.55296 0.51333 0.55667 -0.17005 0.09078  -0.04149 110 GLU A OE2 
667  N N   . LYS A 84  ? 0.51774 0.27090 0.33487 -0.18951 0.07570  -0.02567 111 LYS A N   
668  C CA  . LYS A 84  ? 0.57017 0.28629 0.34712 -0.20027 0.07575  -0.02470 111 LYS A CA  
669  C C   . LYS A 84  ? 0.57561 0.27179 0.33774 -0.19992 0.06677  -0.02515 111 LYS A C   
670  O O   . LYS A 84  ? 0.61989 0.28456 0.34738 -0.20982 0.06590  -0.02467 111 LYS A O   
671  C CB  . LYS A 84  ? 0.58336 0.26117 0.32279 -0.18972 0.07626  -0.01953 111 LYS A CB  
672  C CG  . LYS A 84  ? 0.62002 0.31171 0.36979 -0.18625 0.08353  -0.01836 111 LYS A CG  
673  C CD  . LYS A 84  ? 0.65708 0.30736 0.36416 -0.17958 0.08323  -0.01419 111 LYS A CD  
674  C CE  . LYS A 84  ? 0.72605 0.38717 0.44175 -0.17325 0.08860  -0.01262 111 LYS A CE  
675  N NZ  . LYS A 84  ? 0.81636 0.49213 0.53709 -0.19191 0.09938  -0.01630 111 LYS A NZ  
676  N N   . HIS A 85  ? 0.54458 0.25623 0.32941 -0.18878 0.05997  -0.02624 112 HIS A N   
677  C CA  . HIS A 85  ? 0.59728 0.28711 0.36557 -0.18536 0.05098  -0.02664 112 HIS A CA  
678  C C   . HIS A 85  ? 0.56905 0.29234 0.37235 -0.19009 0.04637  -0.03180 112 HIS A C   
679  O O   . HIS A 85  ? 0.60487 0.31501 0.40064 -0.18297 0.03810  -0.03248 112 HIS A O   
680  C CB  . HIS A 85  ? 0.57984 0.24154 0.32727 -0.16182 0.04519  -0.02234 112 HIS A CB  
681  C CG  . HIS A 85  ? 0.68388 0.31205 0.39512 -0.15561 0.04757  -0.01773 112 HIS A CG  
682  N ND1 . HIS A 85  ? 0.71196 0.29923 0.37924 -0.15915 0.04516  -0.01627 112 HIS A ND1 
683  C CD2 . HIS A 85  ? 0.67291 0.30211 0.38398 -0.14707 0.05168  -0.01462 112 HIS A CD2 
684  C CE1 . HIS A 85  ? 0.79655 0.36127 0.43809 -0.15257 0.04736  -0.01279 112 HIS A CE1 
685  N NE2 . HIS A 85  ? 0.75301 0.34292 0.42098 -0.14529 0.05121  -0.01173 112 HIS A NE2 
686  N N   A VAL A 86  ? 0.56681 0.33317 0.40714 -0.20079 0.05105  -0.03582 113 VAL A N   
687  N N   B VAL A 86  ? 0.56674 0.33293 0.40674 -0.20114 0.05118  -0.03582 113 VAL A N   
688  C CA  A VAL A 86  ? 0.57531 0.37526 0.44901 -0.20459 0.04526  -0.04134 113 VAL A CA  
689  C CA  B VAL A 86  ? 0.57653 0.37758 0.45041 -0.20648 0.04587  -0.04153 113 VAL A CA  
690  C C   A VAL A 86  ? 0.59376 0.37805 0.45057 -0.21835 0.03986  -0.04356 113 VAL A C   
691  C C   B VAL A 86  ? 0.59535 0.37792 0.45047 -0.21863 0.03980  -0.04346 113 VAL A C   
692  O O   A VAL A 86  ? 0.63322 0.39792 0.46508 -0.23266 0.04396  -0.04254 113 VAL A O   
693  O O   B VAL A 86  ? 0.63408 0.39439 0.46208 -0.23235 0.04341  -0.04226 113 VAL A O   
694  C CB  A VAL A 86  ? 0.56874 0.41935 0.48414 -0.21184 0.05120  -0.04556 113 VAL A CB  
695  C CB  B VAL A 86  ? 0.57552 0.42475 0.48741 -0.21683 0.05264  -0.04577 113 VAL A CB  
696  C CG1 A VAL A 86  ? 0.56244 0.41946 0.47351 -0.23226 0.05859  -0.04734 113 VAL A CG1 
697  C CG1 B VAL A 86  ? 0.56924 0.45667 0.51693 -0.22000 0.04542  -0.05208 113 VAL A CG1 
698  C CG2 A VAL A 86  ? 0.51421 0.40104 0.46570 -0.20933 0.04319  -0.05118 113 VAL A CG2 
699  C CG2 B VAL A 86  ? 0.55152 0.41578 0.47795 -0.20489 0.05907  -0.04367 113 VAL A CG2 
700  N N   . ASN A 87  ? 0.55895 0.34851 0.42579 -0.21385 0.03017  -0.04655 114 ASN A N   
701  C CA  . ASN A 87  ? 0.57010 0.34120 0.41899 -0.22365 0.02291  -0.04849 114 ASN A CA  
702  C C   . ASN A 87  ? 0.67181 0.38773 0.46917 -0.21948 0.02185  -0.04351 114 ASN A C   
703  O O   . ASN A 87  ? 0.71801 0.41193 0.49123 -0.23153 0.01864  -0.04403 114 ASN A O   
704  C CB  . ASN A 87  ? 0.66087 0.45687 0.52479 -0.24692 0.02540  -0.05264 114 ASN A CB  
705  C CG  . ASN A 87  ? 0.68391 0.53433 0.59778 -0.24862 0.02265  -0.05863 114 ASN A CG  
706  O OD1 . ASN A 87  ? 0.82600 0.71132 0.76527 -0.25775 0.02970  -0.06095 114 ASN A OD1 
707  N ND2 . ASN A 87  ? 0.70825 0.56611 0.63523 -0.23833 0.01213  -0.06142 114 ASN A ND2 
708  N N   . GLY A 88  ? 0.59473 0.28839 0.37427 -0.20195 0.02406  -0.03874 115 GLY A N   
709  C CA  . GLY A 88  ? 0.70629 0.35053 0.43956 -0.19087 0.02093  -0.03439 115 GLY A CA  
710  C C   . GLY A 88  ? 0.62891 0.26834 0.36413 -0.16553 0.01742  -0.03240 115 GLY A C   
711  O O   . GLY A 88  ? 0.60468 0.27513 0.37386 -0.15938 0.01558  -0.03510 115 GLY A O   
712  N N   . THR A 89  ? 0.67138 0.27421 0.37104 -0.15004 0.01657  -0.02790 116 THR A N   
713  C CA  . THR A 89  ? 0.63048 0.23130 0.33244 -0.12504 0.01365  -0.02615 116 THR A CA  
714  C C   . THR A 89  ? 0.63258 0.22237 0.32215 -0.11259 0.01803  -0.02138 116 THR A C   
715  O O   . THR A 89  ? 0.68954 0.26107 0.35661 -0.12078 0.02179  -0.01908 116 THR A O   
716  C CB  . THR A 89  ? 0.74414 0.31507 0.41702 -0.11135 0.00625  -0.02594 116 THR A CB  
717  O OG1 . THR A 89  ? 0.75980 0.29027 0.38814 -0.11121 0.00589  -0.02271 116 THR A OG1 
718  C CG2 . THR A 89  ? 0.68127 0.26057 0.36371 -0.12297 0.00077  -0.03060 116 THR A CG2 
719  N N   . MET A 90  ? 0.59326 0.19422 0.29669 -0.09262 0.01702  -0.02013 117 MET A N   
720  C CA  . MET A 90  ? 0.58928 0.17936 0.28002 -0.07566 0.01860  -0.01566 117 MET A CA  
721  C C   . MET A 90  ? 0.60137 0.18552 0.28604 -0.05055 0.01319  -0.01509 117 MET A C   
722  O O   . MET A 90  ? 0.60270 0.20410 0.30714 -0.04669 0.01082  -0.01796 117 MET A O   
723  C CB  . MET A 90  ? 0.55819 0.17824 0.27998 -0.07777 0.02447  -0.01456 117 MET A CB  
724  C CG  . MET A 90  ? 0.59796 0.22863 0.32754 -0.10101 0.03132  -0.01542 117 MET A CG  
725  S SD  . MET A 90  ? 0.58779 0.25601 0.35510 -0.10114 0.03810  -0.01451 117 MET A SD  
726  C CE  . MET A 90  ? 0.59184 0.23765 0.33564 -0.07857 0.03657  -0.00849 117 MET A CE  
727  N N   . THR A 91  ? 0.59701 0.15851 0.25425 -0.03310 0.01112  -0.01188 118 THR A N   
728  C CA  . THR A 91  ? 0.61614 0.17929 0.27151 -0.00798 0.00701  -0.01170 118 THR A CA  
729  C C   . THR A 91  ? 0.59740 0.19317 0.28576 0.00316  0.00938  -0.01050 118 THR A C   
730  O O   . THR A 91  ? 0.55874 0.16904 0.26454 -0.00618 0.01365  -0.00895 118 THR A O   
731  C CB  . THR A 91  ? 0.65588 0.18879 0.27335 0.00836  0.00334  -0.00945 118 THR A CB  
732  O OG1 . THR A 91  ? 0.63844 0.17289 0.25510 0.01243  0.00522  -0.00633 118 THR A OG1 
733  C CG2 . THR A 91  ? 0.71752 0.21226 0.29584 -0.00473 0.00111  -0.00991 118 THR A CG2 
734  N N   . LEU A 92  ? 0.54609 0.15419 0.24223 0.02323  0.00699  -0.01112 119 LEU A N   
735  C CA  . LEU A 92  ? 0.53275 0.17159 0.25759 0.03474  0.00899  -0.00947 119 LEU A CA  
736  C C   . LEU A 92  ? 0.53719 0.17398 0.25535 0.04368  0.00923  -0.00534 119 LEU A C   
737  O O   . LEU A 92  ? 0.51401 0.17217 0.25448 0.04380  0.01172  -0.00304 119 LEU A O   
738  C CB  . LEU A 92  ? 0.53779 0.19294 0.27112 0.05424  0.00717  -0.01096 119 LEU A CB  
739  C CG  . LEU A 92  ? 0.53827 0.20620 0.28860 0.04650  0.00735  -0.01486 119 LEU A CG  
740  C CD1 . LEU A 92  ? 0.51267 0.19030 0.26210 0.06538  0.00601  -0.01638 119 LEU A CD1 
741  C CD2 . LEU A 92  ? 0.49239 0.19401 0.27825 0.03684  0.01016  -0.01422 119 LEU A CD2 
742  N N   . ALA A 93  ? 0.55263 0.16287 0.23862 0.05145  0.00598  -0.00446 120 ALA A N   
743  C CA  . ALA A 93  ? 0.54134 0.14675 0.21832 0.05761  0.00523  -0.00123 120 ALA A CA  
744  C C   . ALA A 93  ? 0.57856 0.18000 0.25887 0.03607  0.00980  0.00038  120 ALA A C   
745  O O   . ALA A 93  ? 0.57384 0.18925 0.26742 0.03762  0.01134  0.00311  120 ALA A O   
746  C CB  . ALA A 93  ? 0.64269 0.21672 0.28034 0.06968  0.00012  -0.00143 120 ALA A CB  
747  N N   . GLU A 94  ? 0.58064 0.16531 0.24949 0.01538  0.01222  -0.00137 121 GLU A N   
748  C CA  . GLU A 94  ? 0.57530 0.16123 0.24912 -0.00598 0.01795  -0.00051 121 GLU A CA  
749  C C   . GLU A 94  ? 0.51184 0.13327 0.22605 -0.01287 0.02263  -0.00056 121 GLU A C   
750  O O   . GLU A 94  ? 0.52282 0.15320 0.24584 -0.02033 0.02696  0.00144  121 GLU A O   
751  C CB  . GLU A 94  ? 0.61034 0.17715 0.26684 -0.02718 0.01977  -0.00290 121 GLU A CB  
752  C CG  . GLU A 94  ? 0.63568 0.16054 0.24437 -0.02345 0.01575  -0.00209 121 GLU A CG  
753  C CD  . GLU A 94  ? 0.80132 0.30582 0.39031 -0.04076 0.01565  -0.00437 121 GLU A CD  
754  O OE1 . GLU A 94  ? 0.69976 0.22244 0.31159 -0.05268 0.01705  -0.00714 121 GLU A OE1 
755  O OE2 . GLU A 94  ? 0.90981 0.37848 0.45795 -0.04238 0.01340  -0.00354 121 GLU A OE2 
756  N N   . LEU A 95  ? 0.50366 0.14409 0.24025 -0.01005 0.02167  -0.00304 122 LEU A N   
757  C CA  . LEU A 95  ? 0.43966 0.11153 0.21164 -0.01509 0.02529  -0.00344 122 LEU A CA  
758  C C   . LEU A 95  ? 0.41956 0.10560 0.20223 0.00145  0.02479  0.00075  122 LEU A C   
759  O O   . LEU A 95  ? 0.43889 0.15240 0.24601 -0.00494 0.02824  0.00227  122 LEU A O   
760  C CB  . LEU A 95  ? 0.43257 0.11950 0.22141 -0.01426 0.02293  -0.00755 122 LEU A CB  
761  C CG  . LEU A 95  ? 0.52656 0.20547 0.31192 -0.03524 0.02335  -0.01213 122 LEU A CG  
762  C CD1 . LEU A 95  ? 0.52086 0.20375 0.31059 -0.03052 0.01843  -0.01611 122 LEU A CD1 
763  C CD2 . LEU A 95  ? 0.52513 0.23068 0.33796 -0.05550 0.02897  -0.01384 122 LEU A CD2 
764  N N   . SER A 96  ? 0.47343 0.15496 0.24486 0.02314  0.01967  0.00230  123 SER A N   
765  C CA  . SER A 96  ? 0.43262 0.13303 0.21613 0.03876  0.01806  0.00627  123 SER A CA  
766  C C   . SER A 96  ? 0.47479 0.16421 0.24694 0.03325  0.01925  0.00958  123 SER A C   
767  O O   . SER A 96  ? 0.43927 0.14730 0.22849 0.03302  0.02072  0.01272  123 SER A O   
768  C CB  . SER A 96  ? 0.47900 0.18100 0.25374 0.06242  0.01249  0.00626  123 SER A CB  
769  O OG  . SER A 96  ? 0.48753 0.20011 0.27184 0.06713  0.01237  0.00302  123 SER A OG  
770  N N   . ALA A 97  ? 0.50278 0.16317 0.24470 0.02931  0.01811  0.00886  124 ALA A N   
771  C CA  . ALA A 97  ? 0.50682 0.15419 0.23406 0.02236  0.01960  0.01110  124 ALA A CA  
772  C C   . ALA A 97  ? 0.46239 0.12268 0.20747 0.00151  0.02746  0.01126  124 ALA A C   
773  O O   . ALA A 97  ? 0.49573 0.16206 0.24453 -0.00005 0.02924  0.01390  124 ALA A O   
774  C CB  . ALA A 97  ? 0.56231 0.17342 0.25086 0.01927  0.01766  0.00962  124 ALA A CB  
775  N N   . ALA A 98  ? 0.47201 0.13721 0.22719 -0.01481 0.03201  0.00788  125 ALA A N   
776  C CA  . ALA A 98  ? 0.46893 0.15082 0.24251 -0.03414 0.03986  0.00682  125 ALA A CA  
777  C C   . ALA A 98  ? 0.45807 0.16887 0.26166 -0.02936 0.04137  0.00874  125 ALA A C   
778  O O   . ALA A 98  ? 0.40815 0.13011 0.22051 -0.03617 0.04616  0.01014  125 ALA A O   
779  C CB  . ALA A 98  ? 0.45739 0.14480 0.23980 -0.05141 0.04309  0.00195  125 ALA A CB  
780  N N   . ALA A 99  ? 0.38234 0.11451 0.20490 -0.01723 0.03666  0.00803  126 ALA A N   
781  C CA  . ALA A 99  ? 0.33078 0.10289 0.18566 -0.01102 0.03568  0.00927  126 ALA A CA  
782  C C   . ALA A 99  ? 0.38243 0.15236 0.23085 -0.00164 0.03389  0.01433  126 ALA A C   
783  O O   . ALA A 99  ? 0.37085 0.15926 0.23460 -0.00626 0.03654  0.01565  126 ALA A O   
784  C CB  . ALA A 99  ? 0.31523 0.10767 0.18537 0.00159  0.03027  0.00811  126 ALA A CB  
785  N N   . LEU A 100 ? 0.38455 0.13082 0.20872 0.01231  0.02872  0.01691  127 LEU A N   
786  C CA  . LEU A 100 ? 0.37930 0.12691 0.19914 0.02290  0.02489  0.02151  127 LEU A CA  
787  C C   . LEU A 100 ? 0.38880 0.11178 0.18778 0.01248  0.02874  0.02329  127 LEU A C   
788  O O   . LEU A 100 ? 0.43856 0.17133 0.24375 0.01221  0.02888  0.02628  127 LEU A O   
789  C CB  . LEU A 100 ? 0.38184 0.11744 0.18522 0.04391  0.01691  0.02293  127 LEU A CB  
790  C CG  . LEU A 100 ? 0.36476 0.13313 0.19178 0.05625  0.01346  0.02148  127 LEU A CG  
791  C CD1 . LEU A 100 ? 0.47843 0.23258 0.28628 0.07776  0.00692  0.02144  127 LEU A CD1 
792  C CD2 . LEU A 100 ? 0.43440 0.24404 0.29268 0.05669  0.01244  0.02359  127 LEU A CD2 
793  N N   . GLN A 101 ? 0.43462 0.13297 0.21032 0.00407  0.03070  0.02044  128 GLN A N   
794  C CA  . GLN A 101 ? 0.48076 0.16250 0.23627 -0.00281 0.03260  0.02095  128 GLN A CA  
795  C C   . GLN A 101 ? 0.48388 0.17325 0.24814 -0.02311 0.04258  0.01897  128 GLN A C   
796  O O   . GLN A 101 ? 0.48629 0.16878 0.23959 -0.02809 0.04522  0.01958  128 GLN A O   
797  C CB  . GLN A 101 ? 0.50972 0.15817 0.22996 -0.00086 0.02942  0.01922  128 GLN A CB  
798  C CG  . GLN A 101 ? 0.53011 0.17239 0.24045 0.02140  0.01948  0.02010  128 GLN A CG  
799  C CD  . GLN A 101 ? 0.64137 0.24847 0.31367 0.02477  0.01574  0.01798  128 GLN A CD  
800  O OE1 . GLN A 101 ? 0.69969 0.28861 0.35628 0.01053  0.02021  0.01569  128 GLN A OE1 
801  N NE2 . GLN A 101 ? 0.64166 0.23987 0.29872 0.04364  0.00714  0.01846  128 GLN A NE2 
802  N N   . TYR A 102 ? 0.45140 0.15524 0.23437 -0.03448 0.04802  0.01589  129 TYR A N   
803  C CA  . TYR A 102 ? 0.46205 0.18095 0.25890 -0.05246 0.05765  0.01294  129 TYR A CA  
804  C C   . TYR A 102 ? 0.39151 0.14301 0.22302 -0.05415 0.06068  0.01216  129 TYR A C   
805  O O   . TYR A 102 ? 0.42363 0.19336 0.27087 -0.06675 0.06850  0.00894  129 TYR A O   
806  C CB  . TYR A 102 ? 0.46236 0.17137 0.24975 -0.06775 0.06187  0.00851  129 TYR A CB  
807  C CG  . TYR A 102 ? 0.55871 0.23407 0.30888 -0.06897 0.06050  0.00904  129 TYR A CG  
808  C CD1 . TYR A 102 ? 0.56568 0.23370 0.30280 -0.07999 0.06702  0.00811  129 TYR A CD1 
809  C CD2 . TYR A 102 ? 0.55720 0.20674 0.28290 -0.05785 0.05257  0.01014  129 TYR A CD2 
810  C CE1 . TYR A 102 ? 0.59912 0.23325 0.29856 -0.08164 0.06571  0.00834  129 TYR A CE1 
811  C CE2 . TYR A 102 ? 0.62671 0.24184 0.31360 -0.05855 0.05081  0.01033  129 TYR A CE2 
812  C CZ  . TYR A 102 ? 0.62147 0.22881 0.29546 -0.07096 0.05733  0.00955  129 TYR A CZ  
813  O OH  . TYR A 102 ? 0.77897 0.35013 0.41185 -0.07308 0.05599  0.00939  129 TYR A OH  
814  N N   . SER A 103 ? 0.38811 0.15043 0.23237 -0.04060 0.05444  0.01443  130 SER A N   
815  C CA  . SER A 103 ? 0.34267 0.14574 0.22264 -0.03858 0.05381  0.01227  130 SER A CA  
816  C C   . SER A 103 ? 0.34104 0.16103 0.23947 -0.05039 0.05765  0.00614  130 SER A C   
817  O O   . SER A 103 ? 0.35248 0.20109 0.27591 -0.05437 0.06040  0.00305  130 SER A O   
818  C CB  . SER A 103 ? 0.35992 0.17584 0.24813 -0.03978 0.05716  0.01398  130 SER A CB  
819  O OG  . SER A 103 ? 0.36575 0.20861 0.27548 -0.02851 0.05063  0.01523  130 SER A OG  
820  N N   . ASP A 104 ? 0.35558 0.15771 0.24105 -0.05442 0.05638  0.00412  131 ASP A N   
821  C CA  . ASP A 104 ? 0.33598 0.15120 0.23585 -0.06722 0.05883  -0.00184 131 ASP A CA  
822  C C   . ASP A 104 ? 0.33852 0.18485 0.26633 -0.05804 0.05254  -0.00413 131 ASP A C   
823  O O   . ASP A 104 ? 0.31463 0.15779 0.23886 -0.04425 0.04563  -0.00194 131 ASP A O   
824  C CB  . ASP A 104 ? 0.36859 0.14949 0.24055 -0.07433 0.05804  -0.00280 131 ASP A CB  
825  C CG  . ASP A 104 ? 0.43000 0.22180 0.31373 -0.09125 0.06046  -0.00904 131 ASP A CG  
826  O OD1 . ASP A 104 ? 0.36815 0.18560 0.27567 -0.08728 0.05568  -0.01238 131 ASP A OD1 
827  O OD2 . ASP A 104 ? 0.42242 0.20409 0.29293 -0.10525 0.06452  -0.01072 131 ASP A OD2 
828  N N   . ASN A 105 ? 0.28713 0.16375 0.24177 -0.06479 0.05501  -0.00865 132 ASN A N   
829  C CA  . ASN A 105 ? 0.26411 0.16771 0.24243 -0.05567 0.04852  -0.01058 132 ASN A CA  
830  C C   . ASN A 105 ? 0.30170 0.20475 0.28206 -0.05772 0.04334  -0.01448 132 ASN A C   
831  O O   . ASN A 105 ? 0.26348 0.17690 0.25230 -0.04729 0.03657  -0.01445 132 ASN A O   
832  C CB  . ASN A 105 ? 0.28631 0.22040 0.29015 -0.05907 0.05151  -0.01442 132 ASN A CB  
833  C CG  . ASN A 105 ? 0.33335 0.27112 0.33728 -0.05163 0.05319  -0.01033 132 ASN A CG  
834  O OD1 . ASN A 105 ? 0.29357 0.21678 0.28320 -0.04277 0.05015  -0.00451 132 ASN A OD1 
835  N ND2 . ASN A 105 ? 0.28318 0.24157 0.30335 -0.05423 0.05732  -0.01370 132 ASN A ND2 
836  N N   . THR A 106 ? 0.27522 0.16765 0.24831 -0.07255 0.04643  -0.01823 133 THR A N   
837  C CA  . THR A 106 ? 0.28925 0.17492 0.25861 -0.07523 0.04068  -0.02165 133 THR A CA  
838  C C   . THR A 106 ? 0.32696 0.18428 0.27124 -0.06252 0.03611  -0.01748 133 THR A C   
839  O O   . THR A 106 ? 0.29174 0.15152 0.23791 -0.05412 0.02975  -0.01855 133 THR A O   
840  C CB  . THR A 106 ? 0.32292 0.19956 0.28561 -0.09604 0.04488  -0.02609 133 THR A CB  
841  O OG1 . THR A 106 ? 0.34451 0.25604 0.33618 -0.10577 0.04872  -0.03118 133 THR A OG1 
842  C CG2 . THR A 106 ? 0.36729 0.22990 0.31984 -0.09994 0.03798  -0.02937 133 THR A CG2 
843  N N   . ALA A 107 ? 0.31818 0.14882 0.23813 -0.05958 0.03918  -0.01289 134 ALA A N   
844  C CA  . ALA A 107 ? 0.35126 0.15718 0.24787 -0.04459 0.03464  -0.00947 134 ALA A CA  
845  C C   . ALA A 107 ? 0.34582 0.17495 0.25893 -0.02732 0.03007  -0.00732 134 ALA A C   
846  O O   . ALA A 107 ? 0.30356 0.12750 0.21002 -0.01684 0.02551  -0.00769 134 ALA A O   
847  C CB  . ALA A 107 ? 0.37464 0.15014 0.24338 -0.04249 0.03756  -0.00501 134 ALA A CB  
848  N N   . MET A 108 ? 0.27776 0.13133 0.21042 -0.02503 0.03156  -0.00525 135 MET A N   
849  C CA  . MET A 108 ? 0.23338 0.10884 0.18061 -0.01199 0.02746  -0.00311 135 MET A CA  
850  C C   . MET A 108 ? 0.24422 0.13434 0.20469 -0.01201 0.02338  -0.00708 135 MET A C   
851  O O   . MET A 108 ? 0.25186 0.14478 0.21029 -0.00114 0.01979  -0.00607 135 MET A O   
852  C CB  . MET A 108 ? 0.23096 0.12623 0.19388 -0.01261 0.02942  -0.00071 135 MET A CB  
853  C CG  . MET A 108 ? 0.24970 0.16859 0.22838 -0.00367 0.02511  0.00097  135 MET A CG  
854  S SD  . MET A 108 ? 0.24434 0.15872 0.21103 0.01206  0.02172  0.00557  135 MET A SD  
855  C CE  . MET A 108 ? 0.24490 0.18677 0.22888 0.01537  0.01927  0.00910  135 MET A CE  
856  N N   . ASN A 109 ? 0.25689 0.15721 0.23048 -0.02383 0.02376  -0.01191 136 ASN A N   
857  C CA  . ASN A 109 ? 0.23546 0.14803 0.21989 -0.02317 0.01828  -0.01587 136 ASN A CA  
858  C C   . ASN A 109 ? 0.26184 0.15270 0.22714 -0.02050 0.01519  -0.01731 136 ASN A C   
859  O O   . ASN A 109 ? 0.27042 0.16675 0.23767 -0.01373 0.01051  -0.01843 136 ASN A O   
860  C CB  . ASN A 109 ? 0.23211 0.16190 0.23522 -0.03524 0.01804  -0.02154 136 ASN A CB  
861  C CG  . ASN A 109 ? 0.25657 0.21119 0.27992 -0.03266 0.01858  -0.02126 136 ASN A CG  
862  O OD1 . ASN A 109 ? 0.22534 0.18306 0.24782 -0.02312 0.01811  -0.01662 136 ASN A OD1 
863  N ND2 . ASN A 109 ? 0.24806 0.22088 0.28912 -0.04100 0.01932  -0.02656 136 ASN A ND2 
864  N N   . LYS A 110 ? 0.27247 0.13570 0.21600 -0.02576 0.01759  -0.01744 137 LYS A N   
865  C CA  . LYS A 110 ? 0.28703 0.12511 0.20767 -0.02089 0.01434  -0.01869 137 LYS A CA  
866  C C   . LYS A 110 ? 0.30256 0.13710 0.21337 -0.00185 0.01362  -0.01482 137 LYS A C   
867  O O   . LYS A 110 ? 0.33373 0.16125 0.23497 0.00620  0.01058  -0.01635 137 LYS A O   
868  C CB  . LYS A 110 ? 0.31647 0.11991 0.21035 -0.03088 0.01652  -0.01955 137 LYS A CB  
869  C CG  . LYS A 110 ? 0.37017 0.17796 0.27253 -0.05213 0.01762  -0.02414 137 LYS A CG  
870  C CD  . LYS A 110 ? 0.42350 0.23696 0.33161 -0.05585 0.01109  -0.02926 137 LYS A CD  
871  C CE  . LYS A 110 ? 0.49402 0.31031 0.40794 -0.07810 0.01121  -0.03448 137 LYS A CE  
872  N NZ  . LYS A 110 ? 0.57701 0.39687 0.49450 -0.08193 0.00309  -0.03972 137 LYS A NZ  
873  N N   . LEU A 111 ? 0.29524 0.13331 0.20619 0.00544  0.01645  -0.01016 138 LEU A N   
874  C CA  . LEU A 111 ? 0.29687 0.13979 0.20373 0.02316  0.01565  -0.00692 138 LEU A CA  
875  C C   . LEU A 111 ? 0.27998 0.15178 0.20681 0.02725  0.01388  -0.00705 138 LEU A C   
876  O O   . LEU A 111 ? 0.29485 0.16788 0.21561 0.03829  0.01296  -0.00726 138 LEU A O   
877  C CB  . LEU A 111 ? 0.28870 0.13432 0.19541 0.02831  0.01766  -0.00216 138 LEU A CB  
878  C CG  . LEU A 111 ? 0.33951 0.15232 0.22145 0.02534  0.01912  -0.00145 138 LEU A CG  
879  C CD1 . LEU A 111 ? 0.37162 0.19065 0.25506 0.03234  0.01972  0.00351  138 LEU A CD1 
880  C CD2 . LEU A 111 ? 0.39825 0.17893 0.25059 0.03453  0.01693  -0.00324 138 LEU A CD2 
881  N N   . ILE A 112 ? 0.24708 0.14043 0.19535 0.01859  0.01356  -0.00718 139 ILE A N   
882  C CA  . ILE A 112 ? 0.23731 0.15273 0.19986 0.02124  0.01112  -0.00722 139 ILE A CA  
883  C C   . ILE A 112 ? 0.25115 0.15853 0.20654 0.02121  0.00783  -0.01149 139 ILE A C   
884  O O   . ILE A 112 ? 0.26481 0.17792 0.21736 0.02906  0.00705  -0.01106 139 ILE A O   
885  C CB  . ILE A 112 ? 0.19148 0.12547 0.17379 0.01275  0.01037  -0.00732 139 ILE A CB  
886  C CG1 . ILE A 112 ? 0.19241 0.13297 0.17876 0.01407  0.01337  -0.00263 139 ILE A CG1 
887  C CG2 . ILE A 112 ? 0.24862 0.19871 0.24051 0.01427  0.00628  -0.00808 139 ILE A CG2 
888  C CD1 . ILE A 112 ? 0.21074 0.16539 0.21285 0.00660  0.01334  -0.00314 139 ILE A CD1 
889  N N   . ALA A 113 ? 0.26606 0.15920 0.21658 0.01167  0.00601  -0.01580 140 ALA A N   
890  C CA  . ALA A 113 ? 0.29598 0.17878 0.23737 0.01089  0.00166  -0.02009 140 ALA A CA  
891  C C   . ALA A 113 ? 0.27563 0.13903 0.19371 0.02299  0.00288  -0.01959 140 ALA A C   
892  O O   . ALA A 113 ? 0.30241 0.16450 0.21402 0.02823  0.00072  -0.02134 140 ALA A O   
893  C CB  . ALA A 113 ? 0.33926 0.21093 0.27937 -0.00341 -0.00082 -0.02485 140 ALA A CB  
894  N N   . GLN A 114 ? 0.30232 0.14820 0.20507 0.02815  0.00611  -0.01768 141 GLN A N   
895  C CA  . GLN A 114 ? 0.32920 0.15653 0.20876 0.04272  0.00720  -0.01772 141 GLN A CA  
896  C C   . GLN A 114 ? 0.32821 0.17883 0.21609 0.05604  0.00949  -0.01541 141 GLN A C   
897  O O   . GLN A 114 ? 0.36407 0.20697 0.23724 0.06697  0.01022  -0.01721 141 GLN A O   
898  C CB  . GLN A 114 ? 0.35618 0.16213 0.21875 0.04726  0.00930  -0.01567 141 GLN A CB  
899  C CG  . GLN A 114 ? 0.43219 0.22454 0.27347 0.06742  0.01042  -0.01537 141 GLN A CG  
900  C CD  . GLN A 114 ? 0.51530 0.27885 0.33029 0.07145  0.00829  -0.01989 141 GLN A CD  
901  O OE1 . GLN A 114 ? 0.51140 0.25522 0.31713 0.05749  0.00511  -0.02306 141 GLN A OE1 
902  N NE2 . GLN A 114 ? 0.52093 0.28326 0.32377 0.09059  0.01002  -0.02055 141 GLN A NE2 
903  N N   . LEU A 115 ? 0.31011 0.18843 0.21973 0.05453  0.01098  -0.01170 142 LEU A N   
904  C CA  . LEU A 115 ? 0.25332 0.15666 0.17233 0.06339  0.01348  -0.00908 142 LEU A CA  
905  C C   . LEU A 115 ? 0.30304 0.21945 0.23073 0.05719  0.01164  -0.01026 142 LEU A C   
906  O O   . LEU A 115 ? 0.29194 0.22839 0.22593 0.06106  0.01399  -0.00810 142 LEU A O   
907  C CB  . LEU A 115 ? 0.22871 0.15207 0.16354 0.06289  0.01492  -0.00435 142 LEU A CB  
908  C CG  . LEU A 115 ? 0.29928 0.20796 0.22232 0.07111  0.01587  -0.00295 142 LEU A CG  
909  C CD1 . LEU A 115 ? 0.29481 0.21771 0.23183 0.06673  0.01592  0.00131  142 LEU A CD1 
910  C CD2 . LEU A 115 ? 0.30949 0.22073 0.22205 0.08910  0.01791  -0.00320 142 LEU A CD2 
911  N N   . GLY A 116 ? 0.23322 0.13901 0.16048 0.04722  0.00712  -0.01373 143 GLY A N   
912  C CA  . GLY A 116 ? 0.24876 0.16312 0.18025 0.04323  0.00391  -0.01510 143 GLY A CA  
913  C C   . GLY A 116 ? 0.24407 0.17755 0.19452 0.03539  0.00145  -0.01311 143 GLY A C   
914  O O   . GLY A 116 ? 0.27149 0.21197 0.22263 0.03402  -0.00090 -0.01306 143 GLY A O   
915  N N   . GLY A 117 ? 0.22240 0.16118 0.18502 0.03028  0.00170  -0.01176 144 GLY A N   
916  C CA  . GLY A 117 ? 0.18127 0.13524 0.15939 0.02421  -0.00073 -0.01045 144 GLY A CA  
917  C C   . GLY A 117 ? 0.21311 0.18065 0.19771 0.02665  0.00328  -0.00500 144 GLY A C   
918  O O   . GLY A 117 ? 0.22400 0.19332 0.20319 0.03375  0.00741  -0.00236 144 GLY A O   
919  N N   . PRO A 118 ? 0.17917 0.15675 0.17480 0.02153  0.00144  -0.00355 145 PRO A N   
920  C CA  . PRO A 118 ? 0.16312 0.15231 0.16333 0.02244  0.00417  0.00173  145 PRO A CA  
921  C C   . PRO A 118 ? 0.23430 0.23402 0.23004 0.02639  0.00609  0.00505  145 PRO A C   
922  O O   . PRO A 118 ? 0.22214 0.23201 0.22016 0.02942  0.00901  0.00885  145 PRO A O   
923  C CB  . PRO A 118 ? 0.22059 0.21489 0.22915 0.01639  0.00070  0.00181  145 PRO A CB  
924  C CG  . PRO A 118 ? 0.26957 0.25768 0.28163 0.01343  -0.00306 -0.00392 145 PRO A CG  
925  C CD  . PRO A 118 ? 0.21029 0.18869 0.21388 0.01564  -0.00371 -0.00713 145 PRO A CD  
926  N N   . GLY A 119 ? 0.20007 0.19837 0.18898 0.02626  0.00463  0.00346  146 GLY A N   
927  C CA  . GLY A 119 ? 0.19598 0.20624 0.18017 0.02853  0.00813  0.00632  146 GLY A CA  
928  C C   . GLY A 119 ? 0.24568 0.26026 0.22719 0.03833  0.01353  0.00643  146 GLY A C   
929  O O   . GLY A 119 ? 0.24052 0.27321 0.22419 0.04120  0.01752  0.00930  146 GLY A O   
930  N N   . GLY A 120 ? 0.21642 0.21453 0.19219 0.04364  0.01344  0.00303  147 GLY A N   
931  C CA  . GLY A 120 ? 0.21243 0.20919 0.18148 0.05526  0.01748  0.00261  147 GLY A CA  
932  C C   . GLY A 120 ? 0.23920 0.24403 0.21519 0.05901  0.01838  0.00589  147 GLY A C   
933  O O   . GLY A 120 ? 0.27876 0.29247 0.25274 0.07000  0.02126  0.00664  147 GLY A O   
934  N N   . VAL A 121 ? 0.19739 0.19892 0.18056 0.05110  0.01570  0.00743  148 VAL A N   
935  C CA  . VAL A 121 ? 0.17414 0.18161 0.16184 0.05374  0.01586  0.01086  148 VAL A CA  
936  C C   . VAL A 121 ? 0.22046 0.25466 0.21844 0.05236  0.01628  0.01496  148 VAL A C   
937  O O   . VAL A 121 ? 0.22581 0.27382 0.22642 0.06022  0.01720  0.01700  148 VAL A O   
938  C CB  . VAL A 121 ? 0.19289 0.18799 0.18321 0.04495  0.01390  0.01097  148 VAL A CB  
939  C CG1 . VAL A 121 ? 0.22454 0.22116 0.21533 0.04790  0.01379  0.01456  148 VAL A CG1 
940  C CG2 . VAL A 121 ? 0.24977 0.22123 0.23073 0.04306  0.01381  0.00653  148 VAL A CG2 
941  N N   . THR A 122 ? 0.19357 0.23515 0.19599 0.04237  0.01509  0.01590  149 THR A N   
942  C CA  . THR A 122 ? 0.18091 0.24546 0.19001 0.03767  0.01539  0.01989  149 THR A CA  
943  C C   . THR A 122 ? 0.21530 0.29921 0.22490 0.04527  0.01987  0.01973  149 THR A C   
944  O O   . THR A 122 ? 0.18296 0.29071 0.20071 0.04612  0.02084  0.02263  149 THR A O   
945  C CB  . THR A 122 ? 0.21663 0.27786 0.22381 0.02590  0.01283  0.02043  149 THR A CB  
946  O OG1 . THR A 122 ? 0.19931 0.24583 0.20759 0.02120  0.00903  0.01990  149 THR A OG1 
947  C CG2 . THR A 122 ? 0.25731 0.33828 0.26742 0.01792  0.01287  0.02492  149 THR A CG2 
948  N N   . ALA A 123 ? 0.21595 0.29125 0.21690 0.05100  0.02268  0.01595  150 ALA A N   
949  C CA  . ALA A 123 ? 0.20240 0.29611 0.20250 0.05962  0.02829  0.01492  150 ALA A CA  
950  C C   . ALA A 123 ? 0.21271 0.31928 0.21788 0.07350  0.02938  0.01504  150 ALA A C   
951  O O   . ALA A 123 ? 0.21080 0.34670 0.22391 0.07861  0.03313  0.01571  150 ALA A O   
952  C CB  . ALA A 123 ? 0.26365 0.33833 0.24955 0.06522  0.03038  0.01027  150 ALA A CB  
953  N N   . PHE A 124 ? 0.22661 0.31108 0.22586 0.08018  0.02615  0.01392  151 PHE A N   
954  C CA  . PHE A 124 ? 0.21910 0.30951 0.21869 0.09498  0.02552  0.01389  151 PHE A CA  
955  C C   . PHE A 124 ? 0.21727 0.33472 0.23220 0.09115  0.02302  0.01825  151 PHE A C   
956  O O   . PHE A 124 ? 0.21536 0.35891 0.23805 0.10192  0.02382  0.01832  151 PHE A O   
957  C CB  . PHE A 124 ? 0.21794 0.27320 0.20333 0.09972  0.02217  0.01234  151 PHE A CB  
958  C CG  . PHE A 124 ? 0.27220 0.32748 0.25360 0.11501  0.01978  0.01271  151 PHE A CG  
959  C CD1 . PHE A 124 ? 0.30952 0.37102 0.28446 0.13394  0.02176  0.00965  151 PHE A CD1 
960  C CD2 . PHE A 124 ? 0.31462 0.36285 0.29705 0.11152  0.01526  0.01584  151 PHE A CD2 
961  C CE1 . PHE A 124 ? 0.33555 0.39612 0.30520 0.15040  0.01817  0.00955  151 PHE A CE1 
962  C CE2 . PHE A 124 ? 0.31816 0.36355 0.29407 0.12629  0.01172  0.01620  151 PHE A CE2 
963  C CZ  . PHE A 124 ? 0.34851 0.40000 0.31818 0.14614  0.01260  0.01301  151 PHE A CZ  
964  N N   . ALA A 125 ? 0.19704 0.30987 0.21637 0.07623  0.01967  0.02153  152 ALA A N   
965  C CA  . ALA A 125 ? 0.20978 0.34611 0.24127 0.07024  0.01662  0.02581  152 ALA A CA  
966  C C   . ALA A 125 ? 0.21431 0.38776 0.25725 0.06746  0.02019  0.02672  152 ALA A C   
967  O O   . ALA A 125 ? 0.18791 0.39004 0.24210 0.07239  0.01897  0.02806  152 ALA A O   
968  C CB  . ALA A 125 ? 0.20502 0.32761 0.23585 0.05407  0.01319  0.02864  152 ALA A CB  
969  N N   . ARG A 126 ? 0.19620 0.37017 0.23577 0.05927  0.02459  0.02573  153 ARG A N   
970  C CA  . ARG A 126 ? 0.22753 0.43554 0.27552 0.05369  0.02939  0.02667  153 ARG A CA  
971  C C   . ARG A 126 ? 0.23702 0.47018 0.29144 0.07145  0.03420  0.02340  153 ARG A C   
972  O O   . ARG A 126 ? 0.23364 0.50601 0.30239 0.07083  0.03656  0.02434  153 ARG A O   
973  C CB  . ARG A 126 ? 0.21909 0.41584 0.25668 0.04251  0.03312  0.02598  153 ARG A CB  
974  C CG  . ARG A 126 ? 0.17910 0.35394 0.20965 0.02619  0.02793  0.02876  153 ARG A CG  
975  C CD  . ARG A 126 ? 0.18533 0.37783 0.22160 0.01111  0.02531  0.03362  153 ARG A CD  
976  N NE  . ARG A 126 ? 0.26249 0.42741 0.28754 -0.00095 0.02005  0.03528  153 ARG A NE  
977  C CZ  . ARG A 126 ? 0.24361 0.39010 0.26805 -0.00078 0.01428  0.03608  153 ARG A CZ  
978  N NH1 . ARG A 126 ? 0.21315 0.36348 0.24576 0.00869  0.01259  0.03614  153 ARG A NH1 
979  N NH2 . ARG A 126 ? 0.22529 0.34763 0.23899 -0.00928 0.01017  0.03645  153 ARG A NH2 
980  N N   . ALA A 127 ? 0.21503 0.42640 0.25853 0.08780  0.03531  0.01922  154 ALA A N   
981  C CA  . ALA A 127 ? 0.25341 0.48170 0.29799 0.10713  0.03944  0.01516  154 ALA A CA  
982  C C   . ALA A 127 ? 0.28761 0.52896 0.34000 0.11529  0.03319  0.01564  154 ALA A C   
983  O O   . ALA A 127 ? 0.27526 0.53649 0.33143 0.12382  0.03456  0.01292  154 ALA A O   
984  C CB  . ALA A 127 ? 0.33915 0.53216 0.36422 0.12165  0.04063  0.01065  154 ALA A CB  
985  N N   . ILE A 128 ? 0.27284 0.50354 0.32695 0.11339  0.02637  0.01881  155 ILE A N   
986  C CA  . ILE A 128 ? 0.24782 0.49010 0.30763 0.12012  0.01980  0.01937  155 ILE A CA  
987  C C   . ILE A 128 ? 0.29891 0.57096 0.37546 0.10400  0.01676  0.02375  155 ILE A C   
988  O O   . ILE A 128 ? 0.37008 0.64913 0.45118 0.10702  0.01001  0.02494  155 ILE A O   
989  C CB  . ILE A 128 ? 0.27989 0.48713 0.32582 0.13024  0.01351  0.01959  155 ILE A CB  
990  C CG1 . ILE A 128 ? 0.26322 0.45126 0.30775 0.11677  0.01111  0.02398  155 ILE A CG1 
991  C CG2 . ILE A 128 ? 0.45869 0.63451 0.48440 0.14482  0.01581  0.01493  155 ILE A CG2 
992  C CD1 . ILE A 128 ? 0.31059 0.46374 0.34018 0.12245  0.00506  0.02473  155 ILE A CD1 
993  N N   . GLY A 129 ? 0.18466 0.52542 0.29110 0.07671  0.04104  -0.04269 156 GLY A N   
994  C CA  . GLY A 129 ? 0.25548 0.62805 0.41520 0.05377  0.04340  -0.04752 156 GLY A CA  
995  C C   . GLY A 129 ? 0.24141 0.58594 0.41070 0.03693  0.03323  -0.04393 156 GLY A C   
996  O O   . GLY A 129 ? 0.23527 0.60656 0.45112 0.02131  0.03001  -0.05335 156 GLY A O   
997  N N   . ASP A 130 ? 0.14904 0.43741 0.27645 0.03893  0.02692  -0.03211 157 ASP A N   
998  C CA  . ASP A 130 ? 0.13791 0.39327 0.26768 0.02495  0.01749  -0.02804 157 ASP A CA  
999  C C   . ASP A 130 ? 0.17333 0.40875 0.30390 -0.00046 0.03170  -0.00769 157 ASP A C   
1000 O O   . ASP A 130 ? 0.19709 0.40152 0.29168 0.00213  0.03688  0.00607  157 ASP A O   
1001 C CB  . ASP A 130 ? 0.17727 0.38704 0.26326 0.04318  0.00414  -0.02805 157 ASP A CB  
1002 C CG  . ASP A 130 ? 0.23100 0.41245 0.31840 0.03417  -0.00581 -0.02717 157 ASP A CG  
1003 O OD1 . ASP A 130 ? 0.18535 0.36517 0.29565 0.01199  -0.00196 -0.02074 157 ASP A OD1 
1004 O OD2 . ASP A 130 ? 0.23998 0.39667 0.30107 0.05077  -0.01658 -0.03202 157 ASP A OD2 
1005 N N   . GLU A 131 ? 0.17446 0.42674 0.34583 -0.02403 0.03726  -0.00680 158 GLU A N   
1006 C CA  . GLU A 131 ? 0.20708 0.43491 0.37692 -0.04746 0.05067  0.01355  158 GLU A CA  
1007 C C   . GLU A 131 ? 0.21069 0.39520 0.37352 -0.05520 0.03706  0.01645  158 GLU A C   
1008 O O   . GLU A 131 ? 0.23909 0.39672 0.39863 -0.07234 0.04425  0.03199  158 GLU A O   
1009 C CB  . GLU A 131 ? 0.22198 0.48658 0.43943 -0.07164 0.06816  0.01562  158 GLU A CB  
1010 C CG  . GLU A 131 ? 0.40865 0.71216 0.62597 -0.06683 0.09006  0.02035  158 GLU A CG  
1011 C CD  . GLU A 131 ? 0.69461 1.03451 0.96406 -0.08852 0.10777  0.01947  158 GLU A CD  
1012 O OE1 . GLU A 131 ? 0.78991 1.14993 1.10443 -0.09464 0.09456  0.00276  158 GLU A OE1 
1013 O OE2 . GLU A 131 ? 0.81746 1.15363 1.07649 -0.09532 0.13227  0.03590  158 GLU A OE2 
1014 N N   . THR A 132 ? 0.15298 0.32758 0.30824 -0.04005 0.01804  0.00238  159 THR A N   
1015 C CA  . THR A 132 ? 0.14264 0.28372 0.29528 -0.04478 0.00496  0.00123  159 THR A CA  
1016 C C   . THR A 132 ? 0.14596 0.24909 0.25589 -0.03164 0.00025  0.00849  159 THR A C   
1017 O O   . THR A 132 ? 0.17885 0.25041 0.27889 -0.03892 -0.00189 0.01720  159 THR A O   
1018 C CB  . THR A 132 ? 0.13680 0.29730 0.31336 -0.03658 -0.01221 -0.02155 159 THR A CB  
1019 O OG1 . THR A 132 ? 0.16406 0.36699 0.38950 -0.05000 -0.00903 -0.03217 159 THR A OG1 
1020 C CG2 . THR A 132 ? 0.18010 0.30899 0.35384 -0.03846 -0.02662 -0.02596 159 THR A CG2 
1021 N N   . PHE A 133 ? 0.13875 0.24442 0.22488 -0.01227 -0.00137 0.00419  160 PHE A N   
1022 C CA  . PHE A 133 ? 0.16277 0.23616 0.21422 -0.00223 -0.00348 0.00982  160 PHE A CA  
1023 C C   . PHE A 133 ? 0.17152 0.22467 0.21007 -0.01164 0.00332  0.02465  160 PHE A C   
1024 O O   . PHE A 133 ? 0.18390 0.24753 0.21986 -0.01549 0.01356  0.03260  160 PHE A O   
1025 C CB  . PHE A 133 ? 0.19086 0.26929 0.22042 0.01637  -0.00231 0.00540  160 PHE A CB  
1026 C CG  . PHE A 133 ? 0.20106 0.24700 0.19993 0.02388  -0.00273 0.01002  160 PHE A CG  
1027 C CD1 . PHE A 133 ? 0.23495 0.26966 0.22014 0.02094  0.00245  0.01824  160 PHE A CD1 
1028 C CD2 . PHE A 133 ? 0.22651 0.25392 0.21031 0.03462  -0.00785 0.00506  160 PHE A CD2 
1029 C CE1 . PHE A 133 ? 0.21993 0.22820 0.18492 0.02565  0.00088  0.01909  160 PHE A CE1 
1030 C CE2 . PHE A 133 ? 0.20583 0.20450 0.16736 0.03760  -0.00496 0.00944  160 PHE A CE2 
1031 C CZ  . PHE A 133 ? 0.21422 0.20537 0.17089 0.03166  -0.00157 0.01508  160 PHE A CZ  
1032 N N   . ARG A 134 ? 0.16898 0.19430 0.19611 -0.01189 -0.00246 0.02741  161 ARG A N   
1033 C CA  . ARG A 134 ? 0.18555 0.19263 0.19563 -0.01420 0.00030  0.03802  161 ARG A CA  
1034 C C   . ARG A 134 ? 0.18944 0.17834 0.18642 -0.00632 -0.00578 0.03395  161 ARG A C   
1035 O O   . ARG A 134 ? 0.21258 0.19407 0.21641 -0.00582 -0.01118 0.02872  161 ARG A O   
1036 C CB  . ARG A 134 ? 0.22559 0.21835 0.24173 -0.02674 0.00050  0.04776  161 ARG A CB  
1037 C CG  . ARG A 134 ? 0.22197 0.20324 0.25430 -0.03156 -0.00910 0.04190  161 ARG A CG  
1038 C CD  . ARG A 134 ? 0.22265 0.18458 0.25846 -0.04399 -0.00816 0.05261  161 ARG A CD  
1039 N NE  . ARG A 134 ? 0.25511 0.19326 0.26569 -0.03736 -0.01099 0.06079  161 ARG A NE  
1040 C CZ  . ARG A 134 ? 0.33169 0.24319 0.33160 -0.04205 -0.01155 0.07234  161 ARG A CZ  
1041 N NH1 . ARG A 134 ? 0.32672 0.22870 0.34013 -0.05742 -0.00642 0.07951  161 ARG A NH1 
1042 N NH2 . ARG A 134 ? 0.37375 0.26614 0.34882 -0.03082 -0.01781 0.07633  161 ARG A NH2 
1043 N N   . LEU A 135 ? 0.22741 0.21033 0.20747 -0.00046 -0.00456 0.03521  162 LEU A N   
1044 C CA  . LEU A 135 ? 0.20940 0.17726 0.18451 0.00290  -0.00943 0.03070  162 LEU A CA  
1045 C C   . LEU A 135 ? 0.20810 0.16656 0.17598 0.00247  -0.01444 0.03480  162 LEU A C   
1046 O O   . LEU A 135 ? 0.24623 0.20619 0.19890 0.00567  -0.01229 0.03987  162 LEU A O   
1047 C CB  . LEU A 135 ? 0.23880 0.20338 0.20245 0.01022  -0.00711 0.02525  162 LEU A CB  
1048 C CG  . LEU A 135 ? 0.24538 0.19673 0.21367 0.00881  -0.00880 0.01982  162 LEU A CG  
1049 C CD1 . LEU A 135 ? 0.30823 0.25815 0.28341 0.00837  -0.00518 0.01840  162 LEU A CD1 
1050 C CD2 . LEU A 135 ? 0.31645 0.25717 0.27263 0.01332  -0.00726 0.01514  162 LEU A CD2 
1051 N N   . ASP A 136 ? 0.20958 0.15916 0.18583 0.00128  -0.02144 0.03221  163 ASP A N   
1052 C CA  . ASP A 136 ? 0.22051 0.15934 0.18895 0.00452  -0.02977 0.03471  163 ASP A CA  
1053 C C   . ASP A 136 ? 0.22760 0.16619 0.20265 0.00976  -0.03841 0.02321  163 ASP A C   
1054 O O   . ASP A 136 ? 0.24536 0.17850 0.20927 0.01724  -0.04776 0.02143  163 ASP A O   
1055 C CB  . ASP A 136 ? 0.22021 0.14861 0.19516 0.00111  -0.03388 0.03915  163 ASP A CB  
1056 C CG  . ASP A 136 ? 0.27600 0.20325 0.24946 -0.00747 -0.02596 0.05010  163 ASP A CG  
1057 O OD1 . ASP A 136 ? 0.33223 0.25072 0.28785 -0.00774 -0.02225 0.06150  163 ASP A OD1 
1058 O OD2 . ASP A 136 ? 0.24694 0.18390 0.23646 -0.01305 -0.02269 0.04643  163 ASP A OD2 
1059 N N   . ARG A 137 ? 0.20975 0.15479 0.20293 0.00647  -0.03516 0.01491  164 ARG A N   
1060 C CA  . ARG A 137 ? 0.20501 0.15513 0.21510 0.00747  -0.04066 0.00271  164 ARG A CA  
1061 C C   . ARG A 137 ? 0.19637 0.14802 0.21358 0.00203  -0.03151 -0.00266 164 ARG A C   
1062 O O   . ARG A 137 ? 0.25203 0.19883 0.25781 0.00065  -0.02204 0.00324  164 ARG A O   
1063 C CB  . ARG A 137 ? 0.21162 0.16727 0.24068 0.00781  -0.04265 -0.00195 164 ARG A CB  
1064 C CG  . ARG A 137 ? 0.18964 0.13653 0.21055 0.01559  -0.05554 0.00093  164 ARG A CG  
1065 C CD  . ARG A 137 ? 0.19606 0.14594 0.23229 0.01853  -0.05812 -0.00428 164 ARG A CD  
1066 N NE  . ARG A 137 ? 0.19679 0.14217 0.22984 0.01352  -0.04940 0.00201  164 ARG A NE  
1067 C CZ  . ARG A 137 ? 0.21586 0.16320 0.25854 0.01695  -0.04985 -0.00329 164 ARG A CZ  
1068 N NH1 . ARG A 137 ? 0.23705 0.19032 0.29261 0.02561  -0.05801 -0.01327 164 ARG A NH1 
1069 N NH2 . ARG A 137 ? 0.21034 0.15578 0.24951 0.01427  -0.04340 -0.00085 164 ARG A NH2 
1070 N N   . THR A 138 ? 0.18516 0.14276 0.22279 -0.00069 -0.03520 -0.01494 165 THR A N   
1071 C CA  . THR A 138 ? 0.18311 0.13660 0.23138 -0.00934 -0.02479 -0.01983 165 THR A CA  
1072 C C   . THR A 138 ? 0.20476 0.16553 0.27363 -0.01631 -0.01147 -0.02054 165 THR A C   
1073 O O   . THR A 138 ? 0.21238 0.18319 0.28716 -0.01242 -0.01243 -0.01952 165 THR A O   
1074 C CB  . THR A 138 ? 0.20608 0.16230 0.26990 -0.01127 -0.03541 -0.03465 165 THR A CB  
1075 O OG1 . THR A 138 ? 0.23816 0.21412 0.32988 -0.00991 -0.04553 -0.04639 165 THR A OG1 
1076 C CG2 . THR A 138 ? 0.26551 0.21363 0.30136 0.00002  -0.04866 -0.03458 165 THR A CG2 
1077 N N   . GLU A 139 ? 0.17879 0.13168 0.25592 -0.02585 0.00203  -0.02190 166 GLU A N   
1078 C CA  . GLU A 139 ? 0.17330 0.13443 0.27012 -0.03302 0.01873  -0.02222 166 GLU A CA  
1079 C C   . GLU A 139 ? 0.17505 0.16278 0.31477 -0.03893 0.01359  -0.03800 166 GLU A C   
1080 O O   . GLU A 139 ? 0.21540 0.20712 0.37386 -0.04405 0.00312  -0.05015 166 GLU A O   
1081 C CB  . GLU A 139 ? 0.22458 0.16294 0.31376 -0.04276 0.03857  -0.01602 166 GLU A CB  
1082 C CG  . GLU A 139 ? 0.22290 0.13603 0.26868 -0.03284 0.04310  -0.00239 166 GLU A CG  
1083 C CD  . GLU A 139 ? 0.29222 0.20879 0.32175 -0.02340 0.05126  0.00558  166 GLU A CD  
1084 O OE1 . GLU A 139 ? 0.27297 0.20951 0.32146 -0.02366 0.05428  0.00168  166 GLU A OE1 
1085 O OE2 . GLU A 139 ? 0.30785 0.20842 0.30502 -0.01305 0.05228  0.01353  166 GLU A OE2 
1086 N N   . PRO A 140 ? 0.17579 0.18391 0.33396 -0.03747 0.02082  -0.04072 167 PRO A N   
1087 C CA  . PRO A 140 ? 0.20901 0.21349 0.34808 -0.03095 0.03408  -0.03017 167 PRO A CA  
1088 C C   . PRO A 140 ? 0.18263 0.19197 0.30939 -0.01611 0.01798  -0.02999 167 PRO A C   
1089 O O   . PRO A 140 ? 0.22207 0.22958 0.33480 -0.00867 0.02499  -0.02501 167 PRO A O   
1090 C CB  . PRO A 140 ? 0.22676 0.25402 0.40004 -0.03927 0.05331  -0.03696 167 PRO A CB  
1091 C CG  . PRO A 140 ? 0.22638 0.28289 0.44098 -0.04060 0.03661  -0.05572 167 PRO A CG  
1092 C CD  . PRO A 140 ? 0.21039 0.25053 0.41716 -0.04374 0.01972  -0.05822 167 PRO A CD  
1093 N N   . THR A 141 ? 0.19624 0.20779 0.32385 -0.01008 -0.00346 -0.03495 168 THR A N   
1094 C CA  . THR A 141 ? 0.17477 0.18528 0.29192 0.00247  -0.01659 -0.03398 168 THR A CA  
1095 C C   . THR A 141 ? 0.21118 0.20079 0.29636 0.00528  -0.01641 -0.02081 168 THR A C   
1096 O O   . THR A 141 ? 0.19817 0.18315 0.27642 0.01292  -0.02444 -0.01992 168 THR A O   
1097 C CB  . THR A 141 ? 0.21364 0.22656 0.33480 0.01035  -0.03868 -0.04111 168 THR A CB  
1098 O OG1 . THR A 141 ? 0.23892 0.23745 0.34135 0.00811  -0.04492 -0.03559 168 THR A OG1 
1099 C CG2 . THR A 141 ? 0.25059 0.29184 0.41046 0.01072  -0.04299 -0.05950 168 THR A CG2 
1100 N N   . LEU A 142 ? 0.17232 0.14957 0.24008 -0.00008 -0.00866 -0.01244 169 LEU A N   
1101 C CA  . LEU A 142 ? 0.21743 0.18271 0.26219 0.00326  -0.00991 -0.00350 169 LEU A CA  
1102 C C   . LEU A 142 ? 0.20200 0.16756 0.24146 0.00884  -0.00268 -0.00384 169 LEU A C   
1103 O O   . LEU A 142 ? 0.24645 0.20593 0.27276 0.01269  -0.00676 -0.00075 169 LEU A O   
1104 C CB  . LEU A 142 ? 0.18251 0.13834 0.21036 0.00021  -0.00502 0.00288  169 LEU A CB  
1105 C CG  . LEU A 142 ? 0.21329 0.16130 0.23502 -0.00242 0.00970  0.00409  169 LEU A CG  
1106 C CD1 . LEU A 142 ? 0.24287 0.18435 0.24557 0.00503  0.01671  0.00860  169 LEU A CD1 
1107 C CD2 . LEU A 142 ? 0.24701 0.18442 0.25687 -0.00426 0.00871  0.00607  169 LEU A CD2 
1108 N N   . ASN A 143 ? 0.19271 0.16744 0.24338 0.01007  0.00777  -0.00899 170 ASN A N   
1109 C CA  . ASN A 143 ? 0.20712 0.18158 0.24639 0.01915  0.01601  -0.00979 170 ASN A CA  
1110 C C   . ASN A 143 ? 0.23134 0.21470 0.28040 0.02871  0.00644  -0.01880 170 ASN A C   
1111 O O   . ASN A 143 ? 0.21824 0.20467 0.25892 0.03883  0.01368  -0.02243 170 ASN A O   
1112 C CB  . ASN A 143 ? 0.31222 0.28914 0.35173 0.01636  0.03841  -0.00789 170 ASN A CB  
1113 C CG  . ASN A 143 ? 0.37563 0.33582 0.40173 0.00852  0.04753  0.00068  170 ASN A CG  
1114 O OD1 . ASN A 143 ? 0.28693 0.23091 0.28486 0.01507  0.04670  0.00693  170 ASN A OD1 
1115 N ND2 . ASN A 143 ? 0.30141 0.26541 0.34904 -0.00445 0.05408  -0.00119 170 ASN A ND2 
1116 N N   . THR A 144 ? 0.17392 0.15851 0.23598 0.02854  -0.00978 -0.02277 171 THR A N   
1117 C CA  . THR A 144 ? 0.17899 0.16813 0.24924 0.04007  -0.01998 -0.03270 171 THR A CA  
1118 C C   . THR A 144 ? 0.20729 0.18208 0.26051 0.04842  -0.02781 -0.03414 171 THR A C   
1119 O O   . THR A 144 ? 0.21089 0.18885 0.26521 0.06135  -0.03194 -0.04424 171 THR A O   
1120 C CB  . THR A 144 ? 0.23683 0.22209 0.31706 0.04126  -0.03761 -0.03548 171 THR A CB  
1121 O OG1 . THR A 144 ? 0.23086 0.19581 0.29614 0.03395  -0.04554 -0.02466 171 THR A OG1 
1122 C CG2 . THR A 144 ? 0.21895 0.22530 0.32244 0.03783  -0.03439 -0.04163 171 THR A CG2 
1123 N N   . ALA A 145 ? 0.18518 0.14669 0.22533 0.04222  -0.03110 -0.02675 172 ALA A N   
1124 C CA  . ALA A 145 ? 0.22416 0.17691 0.25274 0.04926  -0.03829 -0.03148 172 ALA A CA  
1125 C C   . ALA A 145 ? 0.22680 0.16810 0.26098 0.05665  -0.05551 -0.04115 172 ALA A C   
1126 O O   . ALA A 145 ? 0.24962 0.18808 0.27687 0.06895  -0.06142 -0.05200 172 ALA A O   
1127 C CB  . ALA A 145 ? 0.24035 0.20015 0.25210 0.06091  -0.02528 -0.03484 172 ALA A CB  
1128 N N   . ILE A 146 ? 0.20372 0.13404 0.24662 0.05129  -0.06526 -0.03781 173 ILE A N   
1129 C CA  A ILE A 146 ? 0.23380 0.14534 0.27871 0.05949  -0.08230 -0.04596 173 ILE A CA  
1130 C CA  B ILE A 146 ? 0.23555 0.14687 0.28050 0.05934  -0.08240 -0.04582 173 ILE A CA  
1131 C C   . ILE A 146 ? 0.27659 0.16845 0.31974 0.05250  -0.09284 -0.04672 173 ILE A C   
1132 O O   . ILE A 146 ? 0.26484 0.15176 0.31056 0.03711  -0.09034 -0.03626 173 ILE A O   
1133 C CB  A ILE A 146 ? 0.24095 0.14235 0.28841 0.05733  -0.08917 -0.04008 173 ILE A CB  
1134 C CB  B ILE A 146 ? 0.24306 0.14365 0.29030 0.05679  -0.08934 -0.03960 173 ILE A CB  
1135 C CG1 A ILE A 146 ? 0.28816 0.21541 0.34670 0.06660  -0.08253 -0.04651 173 ILE A CG1 
1136 C CG1 B ILE A 146 ? 0.28467 0.21090 0.34225 0.06285  -0.08128 -0.04316 173 ILE A CG1 
1137 C CG2 A ILE A 146 ? 0.30157 0.18104 0.34183 0.05896  -0.10349 -0.04240 173 ILE A CG2 
1138 C CG2 B ILE A 146 ? 0.30714 0.19057 0.34828 0.06200  -0.10327 -0.04480 173 ILE A CG2 
1139 C CD1 A ILE A 146 ? 0.32627 0.25188 0.38752 0.06422  -0.08764 -0.04106 173 ILE A CD1 
1140 C CD1 B ILE A 146 ? 0.28585 0.23147 0.35241 0.07929  -0.07929 -0.05857 173 ILE A CD1 
1141 N N   . PRO A 147 ? 0.27453 0.16251 0.31495 0.06084  -0.10274 -0.05887 174 PRO A N   
1142 C CA  . PRO A 147 ? 0.32043 0.19484 0.36639 0.05269  -0.11376 -0.06226 174 PRO A CA  
1143 C C   . PRO A 147 ? 0.34774 0.20093 0.40042 0.03460  -0.11643 -0.04873 174 PRO A C   
1144 O O   . PRO A 147 ? 0.33265 0.17173 0.37879 0.03601  -0.11960 -0.04338 174 PRO A O   
1145 C CB  . PRO A 147 ? 0.36885 0.24109 0.40984 0.06719  -0.12603 -0.07723 174 PRO A CB  
1146 C CG  . PRO A 147 ? 0.39174 0.28372 0.42170 0.08392  -0.11653 -0.08275 174 PRO A CG  
1147 C CD  . PRO A 147 ? 0.31209 0.21161 0.34650 0.07831  -0.10359 -0.07100 174 PRO A CD  
1148 N N   . GLY A 148 ? 0.29015 0.14263 0.35425 0.01840  -0.11366 -0.04342 175 GLY A N   
1149 C CA  . GLY A 148 ? 0.36030 0.19515 0.42921 -0.00033 -0.11025 -0.02884 175 GLY A CA  
1150 C C   . GLY A 148 ? 0.35101 0.18701 0.41158 -0.00863 -0.09726 -0.01093 175 GLY A C   
1151 O O   . GLY A 148 ? 0.35291 0.17825 0.41474 -0.02431 -0.08987 0.00233  175 GLY A O   
1152 N N   . ASP A 149 ? 0.29805 0.14620 0.34940 0.00212  -0.09335 -0.01047 176 ASP A N   
1153 C CA  . ASP A 149 ? 0.29328 0.14353 0.33498 -0.00215 -0.08383 0.00415  176 ASP A CA  
1154 C C   . ASP A 149 ? 0.27679 0.14710 0.32517 -0.01420 -0.07201 0.01023  176 ASP A C   
1155 O O   . ASP A 149 ? 0.26906 0.16291 0.32178 -0.00920 -0.06852 0.00148  176 ASP A O   
1156 C CB  . ASP A 149 ? 0.27163 0.13653 0.30826 0.01267  -0.08297 -0.00140 176 ASP A CB  
1157 C CG  . ASP A 149 ? 0.29518 0.16447 0.32183 0.01130  -0.07685 0.00942  176 ASP A CG  
1158 O OD1 . ASP A 149 ? 0.30951 0.16858 0.32742 0.00101  -0.07210 0.02316  176 ASP A OD1 
1159 O OD2 . ASP A 149 ? 0.29281 0.17737 0.32159 0.02119  -0.07667 0.00263  176 ASP A OD2 
1160 N N   . PRO A 150 ? 0.28119 0.14540 0.32747 -0.02779 -0.06406 0.02487  177 PRO A N   
1161 C CA  . PRO A 150 ? 0.25499 0.14666 0.30931 -0.03626 -0.05206 0.02777  177 PRO A CA  
1162 C C   . PRO A 150 ? 0.20831 0.11856 0.24851 -0.02792 -0.04387 0.03053  177 PRO A C   
1163 O O   . PRO A 150 ? 0.21494 0.14764 0.25886 -0.02999 -0.03579 0.03011  177 PRO A O   
1164 C CB  . PRO A 150 ? 0.31286 0.19117 0.36963 -0.05361 -0.04370 0.04326  177 PRO A CB  
1165 C CG  . PRO A 150 ? 0.35586 0.20152 0.38993 -0.04810 -0.04750 0.05232  177 PRO A CG  
1166 C CD  . PRO A 150 ? 0.35235 0.18896 0.38750 -0.03457 -0.06262 0.03748  177 PRO A CD  
1167 N N   . ARG A 151 ? 0.21675 0.11895 0.24313 -0.01802 -0.04700 0.03130  178 ARG A N   
1168 C CA  . ARG A 151 ? 0.19517 0.11228 0.21192 -0.01265 -0.04046 0.03220  178 ARG A CA  
1169 C C   . ARG A 151 ? 0.18022 0.11638 0.20235 -0.00831 -0.03571 0.02300  178 ARG A C   
1170 O O   . ARG A 151 ? 0.19268 0.12998 0.22083 -0.00294 -0.03919 0.01386  178 ARG A O   
1171 C CB  . ARG A 151 ? 0.22456 0.13373 0.23399 -0.00316 -0.04741 0.02971  178 ARG A CB  
1172 C CG  . ARG A 151 ? 0.26163 0.14771 0.25429 -0.00186 -0.05295 0.04025  178 ARG A CG  
1173 C CD  . ARG A 151 ? 0.29432 0.17602 0.28233 0.01206  -0.06480 0.03297  178 ARG A CD  
1174 N NE  . ARG A 151 ? 0.32749 0.20766 0.32948 0.01879  -0.07344 0.02166  178 ARG A NE  
1175 C CZ  . ARG A 151 ? 0.38354 0.26940 0.39190 0.03160  -0.08342 0.01040  178 ARG A CZ  
1176 N NH1 . ARG A 151 ? 0.32234 0.21469 0.32592 0.03916  -0.08908 0.00735  178 ARG A NH1 
1177 N NH2 . ARG A 151 ? 0.32900 0.21734 0.35065 0.03859  -0.08881 -0.00059 178 ARG A NH2 
1178 N N   . ASP A 152 ? 0.17005 0.11818 0.18539 -0.00829 -0.02763 0.02560  179 ASP A N   
1179 C CA  . ASP A 152 ? 0.15520 0.11247 0.16722 -0.00179 -0.02252 0.01921  179 ASP A CA  
1180 C C   . ASP A 152 ? 0.17690 0.14056 0.19428 0.00161  -0.02472 0.01228  179 ASP A C   
1181 O O   . ASP A 152 ? 0.19514 0.15776 0.20618 0.01046  -0.02331 0.00621  179 ASP A O   
1182 C CB  . ASP A 152 ? 0.17400 0.12680 0.18594 0.00266  -0.02159 0.01469  179 ASP A CB  
1183 C CG  . ASP A 152 ? 0.21066 0.15997 0.22161 0.00104  -0.02454 0.01694  179 ASP A CG  
1184 O OD1 . ASP A 152 ? 0.21420 0.16485 0.21593 0.00044  -0.02138 0.01998  179 ASP A OD1 
1185 O OD2 . ASP A 152 ? 0.22538 0.17118 0.24317 0.00306  -0.03152 0.01386  179 ASP A OD2 
1186 N N   . THR A 153 ? 0.18538 0.12317 0.23915 -0.01131 -0.01468 0.01254  180 THR A N   
1187 C CA  . THR A 153 ? 0.16349 0.12826 0.20603 -0.01842 0.00227  0.01537  180 THR A CA  
1188 C C   . THR A 153 ? 0.17042 0.16345 0.19732 -0.01237 0.00194  0.00865  180 THR A C   
1189 O O   . THR A 153 ? 0.19380 0.18577 0.20780 -0.00381 -0.00459 0.00301  180 THR A O   
1190 C CB  . THR A 153 ? 0.17731 0.14428 0.20315 -0.03414 0.01309  0.01516  180 THR A CB  
1191 O OG1 . THR A 153 ? 0.21111 0.18067 0.21786 -0.03748 0.01255  0.00908  180 THR A OG1 
1192 C CG2 . THR A 153 ? 0.19702 0.13713 0.23714 -0.03913 0.01683  0.02329  180 THR A CG2 
1193 N N   . THR A 154 ? 0.17059 0.18506 0.19609 -0.01348 0.00872  0.00956  181 THR A N   
1194 C CA  . THR A 154 ? 0.17116 0.21769 0.19018 -0.01205 0.00940  0.00334  181 THR A CA  
1195 C C   . THR A 154 ? 0.16609 0.22579 0.18252 -0.01991 0.01177  0.00151  181 THR A C   
1196 O O   . THR A 154 ? 0.19741 0.23705 0.20654 -0.02415 0.01483  0.00514  181 THR A O   
1197 C CB  . THR A 154 ? 0.17852 0.23342 0.20158 0.00502  0.00270  0.00223  181 THR A CB  
1198 O OG1 . THR A 154 ? 0.18943 0.27506 0.21037 0.00755  0.00505  -0.00272 181 THR A OG1 
1199 C CG2 . THR A 154 ? 0.17901 0.23018 0.20688 0.01346  0.00302  0.00734  181 THR A CG2 
1200 N N   . THR A 155 ? 0.17877 0.26906 0.20185 -0.02012 0.00862  -0.00463 182 THR A N   
1201 C CA  . THR A 155 ? 0.17473 0.27204 0.19571 -0.02343 0.00112  -0.01022 182 THR A CA  
1202 C C   . THR A 155 ? 0.15925 0.26391 0.17331 -0.00541 -0.00786 -0.01285 182 THR A C   
1203 O O   . THR A 155 ? 0.17488 0.29371 0.19673 0.00482  -0.00747 -0.01175 182 THR A O   
1204 C CB  . THR A 155 ? 0.20111 0.32711 0.24791 -0.03775 -0.00121 -0.01636 182 THR A CB  
1205 O OG1 . THR A 155 ? 0.16570 0.32405 0.23470 -0.03056 -0.00035 -0.01717 182 THR A OG1 
1206 C CG2 . THR A 155 ? 0.18611 0.30311 0.23748 -0.05359 0.01181  -0.01159 182 THR A CG2 
1207 N N   . PRO A 156 ? 0.19382 0.28769 0.18926 0.00119  -0.01807 -0.01787 183 PRO A N   
1208 C CA  . PRO A 156 ? 0.19786 0.29420 0.17925 0.02243  -0.02747 -0.02069 183 PRO A CA  
1209 C C   . PRO A 156 ? 0.22301 0.36080 0.23446 0.02231  -0.03779 -0.02864 183 PRO A C   
1210 O O   . PRO A 156 ? 0.20479 0.35041 0.21419 0.03764  -0.03762 -0.02659 183 PRO A O   
1211 C CB  . PRO A 156 ? 0.23687 0.30709 0.18389 0.03173  -0.04088 -0.02777 183 PRO A CB  
1212 C CG  . PRO A 156 ? 0.23993 0.27965 0.17291 0.02124  -0.02769 -0.02058 183 PRO A CG  
1213 C CD  . PRO A 156 ? 0.20272 0.27002 0.17699 -0.00428 -0.02121 -0.02021 183 PRO A CD  
1214 N N   . ARG A 157 ? 0.18078 0.34544 0.22619 0.00580  -0.04444 -0.03572 184 ARG A N   
1215 C CA  . ARG A 157 ? 0.18711 0.39336 0.27246 0.00672  -0.05045 -0.04015 184 ARG A CA  
1216 C C   . ARG A 157 ? 0.23589 0.45414 0.32607 0.01259  -0.03167 -0.03070 184 ARG A C   
1217 O O   . ARG A 157 ? 0.16645 0.40231 0.26212 0.02712  -0.03499 -0.03169 184 ARG A O   
1218 C CB  . ARG A 157 ? 0.16907 0.40064 0.30446 -0.01326 -0.05508 -0.04462 184 ARG A CB  
1219 C CG  . ARG A 157 ? 0.26767 0.54538 0.45960 -0.01186 -0.05699 -0.04550 184 ARG A CG  
1220 C CD  . ARG A 157 ? 0.25383 0.55678 0.50513 -0.03166 -0.04270 -0.03906 184 ARG A CD  
1221 N NE  . ARG A 157 ? 0.27984 0.57787 0.55917 -0.04834 -0.06315 -0.04860 184 ARG A NE  
1222 C CZ  . ARG A 157 ? 0.41155 0.73265 0.74913 -0.05254 -0.09024 -0.05949 184 ARG A CZ  
1223 N NH1 . ARG A 157 ? 0.41690 0.76146 0.78026 -0.04042 -0.09767 -0.05872 184 ARG A NH1 
1224 N NH2 . ARG A 157 ? 0.39009 0.69170 0.74004 -0.06689 -0.10739 -0.06479 184 ARG A NH2 
1225 N N   . ALA A 158 ? 0.16500 0.36793 0.24696 0.00470  -0.01473 -0.02269 185 ALA A N   
1226 C CA  . ALA A 158 ? 0.17817 0.38307 0.25598 0.01459  -0.00192 -0.01638 185 ALA A CA  
1227 C C   . ALA A 158 ? 0.17806 0.36513 0.23264 0.03261  -0.00779 -0.01547 185 ALA A C   
1228 O O   . ALA A 158 ? 0.18728 0.38611 0.24292 0.04710  -0.00716 -0.01522 185 ALA A O   
1229 C CB  . ALA A 158 ? 0.21421 0.39701 0.28013 0.00642  0.01146  -0.01045 185 ALA A CB  
1230 N N   . MET A 159 ? 0.15529 0.31295 0.19190 0.03355  -0.01137 -0.01327 186 MET A N   
1231 C CA  . MET A 159 ? 0.17779 0.31626 0.20359 0.05006  -0.01304 -0.00863 186 MET A CA  
1232 C C   . MET A 159 ? 0.19629 0.35138 0.21876 0.06574  -0.02085 -0.01222 186 MET A C   
1233 O O   . MET A 159 ? 0.21502 0.36784 0.23614 0.08072  -0.02184 -0.00987 186 MET A O   
1234 C CB  . MET A 159 ? 0.19985 0.30239 0.21663 0.04905  -0.00801 -0.00036 186 MET A CB  
1235 C CG  . MET A 159 ? 0.22899 0.30928 0.25148 0.06423  -0.00596 0.00860  186 MET A CG  
1236 S SD  . MET A 159 ? 0.27278 0.34537 0.31138 0.06502  -0.01408 0.00604  186 MET A SD  
1237 C CE  . MET A 159 ? 0.39074 0.42578 0.44999 0.05663  -0.01243 0.01481  186 MET A CE  
1238 N N   . ALA A 160 ? 0.19844 0.36701 0.21934 0.06424  -0.03003 -0.01926 187 ALA A N   
1239 C CA  . ALA A 160 ? 0.18281 0.36481 0.19842 0.08181  -0.04212 -0.02476 187 ALA A CA  
1240 C C   . ALA A 160 ? 0.18151 0.40022 0.22384 0.08498  -0.04286 -0.02776 187 ALA A C   
1241 O O   . ALA A 160 ? 0.22197 0.44430 0.25786 0.10252  -0.04556 -0.02723 187 ALA A O   
1242 C CB  . ALA A 160 ? 0.23099 0.41438 0.23953 0.08197  -0.06010 -0.03537 187 ALA A CB  
1243 N N   . GLN A 161 ? 0.17124 0.41444 0.24272 0.07041  -0.03661 -0.02853 188 GLN A N   
1244 C CA  . GLN A 161 ? 0.20814 0.48392 0.30448 0.07749  -0.03073 -0.02768 188 GLN A CA  
1245 C C   . GLN A 161 ? 0.17940 0.43664 0.25214 0.09157  -0.02135 -0.02192 188 GLN A C   
1246 O O   . GLN A 161 ? 0.23017 0.50084 0.30390 0.10834  -0.02191 -0.02220 188 GLN A O   
1247 C CB  . GLN A 161 ? 0.21224 0.51202 0.34555 0.06156  -0.01869 -0.02483 188 GLN A CB  
1248 C CG  . GLN A 161 ? 0.34992 0.67012 0.52092 0.04766  -0.03431 -0.03262 188 GLN A CG  
1249 C CD  . GLN A 161 ? 0.66582 1.00469 0.88136 0.02889  -0.01942 -0.02679 188 GLN A CD  
1250 O OE1 . GLN A 161 ? 0.69610 1.01896 0.89524 0.02425  0.00238  -0.01745 188 GLN A OE1 
1251 N NE2 . GLN A 161 ? 0.61132 0.98121 0.88622 0.01949  -0.03259 -0.03214 188 GLN A NE2 
1252 N N   . THR A 162 ? 0.18909 0.41333 0.24244 0.08603  -0.01581 -0.01785 189 THR A N   
1253 C CA  . THR A 162 ? 0.25109 0.45053 0.28488 0.10049  -0.01543 -0.01560 189 THR A CA  
1254 C C   . THR A 162 ? 0.29876 0.48357 0.32504 0.11462  -0.02543 -0.01525 189 THR A C   
1255 O O   . THR A 162 ? 0.25209 0.42760 0.26846 0.12730  -0.02772 -0.01612 189 THR A O   
1256 C CB  . THR A 162 ? 0.23499 0.40050 0.25688 0.09172  -0.01363 -0.01330 189 THR A CB  
1257 O OG1 . THR A 162 ? 0.22850 0.40377 0.24991 0.08572  -0.00069 -0.01185 189 THR A OG1 
1258 C CG2 . THR A 162 ? 0.25224 0.38424 0.25817 0.10815  -0.02345 -0.01429 189 THR A CG2 
1259 N N   . LEU A 163 ? 0.18221 0.35391 0.20690 0.11064  -0.02782 -0.01245 190 LEU A N   
1260 C CA  . LEU A 163 ? 0.21898 0.36884 0.23519 0.12318  -0.02987 -0.00804 190 LEU A CA  
1261 C C   . LEU A 163 ? 0.24480 0.41211 0.25408 0.13136  -0.03300 -0.01324 190 LEU A C   
1262 O O   . LEU A 163 ? 0.26366 0.41424 0.26549 0.13905  -0.03313 -0.01142 190 LEU A O   
1263 C CB  . LEU A 163 ? 0.24174 0.37310 0.25116 0.12600  -0.02574 -0.00048 190 LEU A CB  
1264 C CG  . LEU A 163 ? 0.22885 0.32774 0.23226 0.13656  -0.01924 0.00950  190 LEU A CG  
1265 C CD1 . LEU A 163 ? 0.27449 0.34784 0.30227 0.12988  -0.01903 0.01476  190 LEU A CD1 
1266 C CD2 . LEU A 163 ? 0.28605 0.36082 0.27451 0.14430  -0.00764 0.02057  190 LEU A CD2 
1267 N N   . ARG A 164 ? 0.21581 0.41621 0.23339 0.12888  -0.03732 -0.01990 191 ARG A N   
1268 C CA  . ARG A 164 ? 0.21429 0.43319 0.23449 0.13636  -0.04170 -0.02508 191 ARG A CA  
1269 C C   . ARG A 164 ? 0.25968 0.48159 0.28086 0.14112  -0.03530 -0.02370 191 ARG A C   
1270 O O   . ARG A 164 ? 0.29764 0.51132 0.30730 0.15118  -0.03666 -0.02416 191 ARG A O   
1271 C CB  . ARG A 164 ? 0.20811 0.46236 0.25469 0.12962  -0.05001 -0.03223 191 ARG A CB  
1272 C CG  . ARG A 164 ? 0.24363 0.51476 0.29989 0.13891  -0.05798 -0.03737 191 ARG A CG  
1273 C CD  . ARG A 164 ? 0.22780 0.53810 0.33279 0.12951  -0.06310 -0.04093 191 ARG A CD  
1274 N NE  . ARG A 164 ? 0.35579 0.68042 0.47610 0.13888  -0.07347 -0.04519 191 ARG A NE  
1275 C CZ  . ARG A 164 ? 0.47745 0.82609 0.64035 0.13429  -0.09021 -0.05131 191 ARG A CZ  
1276 N NH1 . ARG A 164 ? 0.46438 0.82484 0.65960 0.11910  -0.09872 -0.05437 191 ARG A NH1 
1277 N NH2 . ARG A 164 ? 0.40491 0.76405 0.58132 0.14462  -0.10073 -0.05454 191 ARG A NH2 
1278 N N   A GLN A 165 ? 0.24788 0.47889 0.27753 0.13746  -0.02786 -0.02186 192 GLN A N   
1279 N N   B GLN A 165 ? 0.24738 0.48017 0.27810 0.13738  -0.02782 -0.02197 192 GLN A N   
1280 C CA  A GLN A 165 ? 0.25232 0.48307 0.27280 0.14980  -0.02141 -0.02039 192 GLN A CA  
1281 C CA  B GLN A 165 ? 0.25302 0.48330 0.27325 0.14975  -0.02145 -0.02038 192 GLN A CA  
1282 C C   A GLN A 165 ? 0.30168 0.49077 0.29498 0.15826  -0.02737 -0.02103 192 GLN A C   
1283 C C   B GLN A 165 ? 0.29659 0.48597 0.29075 0.15763  -0.02799 -0.02110 192 GLN A C   
1284 O O   A GLN A 165 ? 0.29938 0.48310 0.27837 0.17114  -0.02753 -0.02232 192 GLN A O   
1285 O O   B GLN A 165 ? 0.30348 0.48877 0.28614 0.16868  -0.02924 -0.02250 192 GLN A O   
1286 C CB  A GLN A 165 ? 0.27493 0.51796 0.30208 0.15027  -0.00858 -0.01669 192 GLN A CB  
1287 C CB  B GLN A 165 ? 0.28112 0.51745 0.30346 0.15082  -0.00983 -0.01696 192 GLN A CB  
1288 C CG  A GLN A 165 ? 0.31885 0.60529 0.38673 0.14170  0.00266  -0.01361 192 GLN A CG  
1289 C CG  B GLN A 165 ? 0.34966 0.62623 0.40415 0.14834  0.00578  -0.01229 192 GLN A CG  
1290 C CD  A GLN A 165 ? 0.35464 0.66201 0.43873 0.15118  0.00579  -0.01194 192 GLN A CD  
1291 C CD  B GLN A 165 ? 0.43663 0.70889 0.48433 0.15230  0.02560  -0.00544 192 GLN A CD  
1292 O OE1 A GLN A 165 ? 0.44571 0.74095 0.50615 0.16861  0.01312  -0.00841 192 GLN A OE1 
1293 O OE1 B GLN A 165 ? 0.42502 0.70703 0.49075 0.13711  0.03220  -0.00382 192 GLN A OE1 
1294 N NE2 A GLN A 165 ? 0.38118 0.71687 0.50502 0.14169  -0.00266 -0.01538 192 GLN A NE2 
1295 N NE2 B GLN A 165 ? 0.40999 0.66109 0.42449 0.17415  0.03576  -0.00098 192 GLN A NE2 
1296 N N   . LEU A 166 ? 0.24698 0.40594 0.23898 0.15054  -0.03262 -0.01962 193 LEU A N   
1297 C CA  . LEU A 166 ? 0.28813 0.40729 0.27264 0.15360  -0.04046 -0.01952 193 LEU A CA  
1298 C C   . LEU A 166 ? 0.30584 0.41865 0.29193 0.15661  -0.04178 -0.01720 193 LEU A C   
1299 O O   . LEU A 166 ? 0.31559 0.40671 0.29800 0.16211  -0.04765 -0.01821 193 LEU A O   
1300 C CB  . LEU A 166 ? 0.27379 0.36683 0.27292 0.14246  -0.04444 -0.01522 193 LEU A CB  
1301 C CG  . LEU A 166 ? 0.26875 0.35656 0.26127 0.14161  -0.04648 -0.01849 193 LEU A CG  
1302 C CD1 . LEU A 166 ? 0.26218 0.32399 0.27589 0.12938  -0.05127 -0.01327 193 LEU A CD1 
1303 C CD2 . LEU A 166 ? 0.32234 0.38862 0.28817 0.15604  -0.05398 -0.02588 193 LEU A CD2 
1304 N N   . THR A 167 ? 0.28400 0.41075 0.27363 0.15469  -0.03785 -0.01421 194 THR A N   
1305 C CA  . THR A 167 ? 0.28140 0.39526 0.26793 0.16063  -0.03730 -0.00974 194 THR A CA  
1306 C C   . THR A 167 ? 0.41830 0.55506 0.39186 0.17080  -0.03833 -0.01530 194 THR A C   
1307 O O   . THR A 167 ? 0.45529 0.58131 0.42181 0.17881  -0.03917 -0.01413 194 THR A O   
1308 C CB  . THR A 167 ? 0.33393 0.43634 0.32249 0.15920  -0.03163 -0.00136 194 THR A CB  
1309 O OG1 . THR A 167 ? 0.29951 0.42723 0.27867 0.15987  -0.03289 -0.00692 194 THR A OG1 
1310 C CG2 . THR A 167 ? 0.32333 0.40228 0.33399 0.14901  -0.02918 0.00630  194 THR A CG2 
1311 N N   . LEU A 168 ? 0.41042 0.34107 0.26617 0.21524  -0.05297 -0.00633 195 LEU A N   
1312 C CA  . LEU A 168 ? 0.46443 0.40055 0.31975 0.22804  -0.06068 -0.01022 195 LEU A CA  
1313 C C   . LEU A 168 ? 0.47813 0.44041 0.35013 0.23575  -0.06007 -0.01395 195 LEU A C   
1314 O O   . LEU A 168 ? 0.53379 0.49569 0.39964 0.24965  -0.06660 -0.01889 195 LEU A O   
1315 C CB  . LEU A 168 ? 0.48596 0.43359 0.35334 0.22520  -0.06425 -0.00881 195 LEU A CB  
1316 C CG  . LEU A 168 ? 0.54819 0.46993 0.39711 0.21896  -0.06514 -0.00551 195 LEU A CG  
1317 C CD1 . LEU A 168 ? 0.53967 0.47679 0.40438 0.21476  -0.06811 -0.00395 195 LEU A CD1 
1318 C CD2 . LEU A 168 ? 0.56968 0.45610 0.38369 0.23016  -0.07185 -0.00809 195 LEU A CD2 
1319 N N   . GLY A 169 ? 0.43440 0.41834 0.32596 0.22751  -0.05257 -0.01193 196 GLY A N   
1320 C CA  . GLY A 169 ? 0.46791 0.47641 0.37447 0.23339  -0.05009 -0.01480 196 GLY A CA  
1321 C C   . GLY A 169 ? 0.44129 0.43760 0.33330 0.23798  -0.04766 -0.01687 196 GLY A C   
1322 O O   . GLY A 169 ? 0.51359 0.48045 0.38155 0.24076  -0.05036 -0.01762 196 GLY A O   
1323 N N   . HIS A 170 ? 0.42187 0.44058 0.32802 0.23937  -0.04279 -0.01799 197 HIS A N   
1324 C CA  . HIS A 170 ? 0.43201 0.44260 0.32538 0.24647  -0.04145 -0.02109 197 HIS A CA  
1325 C C   . HIS A 170 ? 0.41572 0.43561 0.31681 0.23695  -0.03313 -0.01817 197 HIS A C   
1326 O O   . HIS A 170 ? 0.43775 0.46574 0.33861 0.24284  -0.03044 -0.02068 197 HIS A O   
1327 C CB  . HIS A 170 ? 0.45627 0.48231 0.35422 0.26200  -0.04499 -0.02707 197 HIS A CB  
1328 C CG  . HIS A 170 ? 0.48355 0.49492 0.36827 0.27372  -0.05469 -0.03112 197 HIS A CG  
1329 N ND1 . HIS A 170 ? 0.66124 0.64500 0.51977 0.28403  -0.06039 -0.03489 197 HIS A ND1 
1330 C CD2 . HIS A 170 ? 0.58399 0.60227 0.47644 0.27671  -0.06040 -0.03202 197 HIS A CD2 
1331 C CE1 . HIS A 170 ? 0.71234 0.68627 0.56212 0.29323  -0.06917 -0.03788 197 HIS A CE1 
1332 N NE2 . HIS A 170 ? 0.67280 0.66754 0.54282 0.28915  -0.06946 -0.03634 197 HIS A NE2 
1333 N N   . ALA A 171 ? 0.39513 0.41274 0.30170 0.22271  -0.02931 -0.01319 198 ALA A N   
1334 C CA  . ALA A 171 ? 0.42478 0.44644 0.33508 0.21407  -0.02271 -0.01082 198 ALA A CA  
1335 C C   . ALA A 171 ? 0.41500 0.41197 0.30256 0.21760  -0.02343 -0.01312 198 ALA A C   
1336 O O   . ALA A 171 ? 0.43592 0.43688 0.32295 0.21625  -0.01941 -0.01328 198 ALA A O   
1337 C CB  . ALA A 171 ? 0.39817 0.42161 0.31875 0.19900  -0.01966 -0.00580 198 ALA A CB  
1338 N N   . LEU A 172 ? 0.38813 0.35857 0.25576 0.22235  -0.02883 -0.01493 199 LEU A N   
1339 C CA  . LEU A 172 ? 0.45499 0.39876 0.29948 0.22653  -0.03072 -0.01755 199 LEU A CA  
1340 C C   . LEU A 172 ? 0.48750 0.42083 0.31641 0.24235  -0.03705 -0.02267 199 LEU A C   
1341 O O   . LEU A 172 ? 0.49905 0.43815 0.33095 0.24920  -0.04129 -0.02398 199 LEU A O   
1342 C CB  . LEU A 172 ? 0.41483 0.33122 0.24613 0.21808  -0.03172 -0.01516 199 LEU A CB  
1343 C CG  . LEU A 172 ? 0.38412 0.30793 0.22954 0.20296  -0.02642 -0.01081 199 LEU A CG  
1344 C CD1 . LEU A 172 ? 0.39852 0.29509 0.22949 0.19770  -0.02820 -0.00913 199 LEU A CD1 
1345 C CD2 . LEU A 172 ? 0.42683 0.35204 0.27304 0.19935  -0.02273 -0.01161 199 LEU A CD2 
1346 N N   . GLY A 173 ? 0.46371 0.37992 0.27522 0.24832  -0.03853 -0.02594 200 GLY A N   
1347 C CA  . GLY A 173 ? 0.49934 0.39863 0.29162 0.26302  -0.04558 -0.03102 200 GLY A CA  
1348 C C   . GLY A 173 ? 0.56228 0.43374 0.33684 0.26406  -0.05163 -0.03035 200 GLY A C   
1349 O O   . GLY A 173 ? 0.51132 0.37107 0.28422 0.25302  -0.04992 -0.02610 200 GLY A O   
1350 N N   A GLU A 174 ? 0.55327 0.41230 0.31234 0.27834  -0.05911 -0.03493 201 GLU A N   
1351 N N   B GLU A 174 ? 0.55333 0.41235 0.31235 0.27838  -0.05909 -0.03496 201 GLU A N   
1352 C CA  A GLU A 174 ? 0.57725 0.41095 0.31836 0.28119  -0.06567 -0.03447 201 GLU A CA  
1353 C CA  B GLU A 174 ? 0.57798 0.41176 0.31889 0.28169  -0.06581 -0.03467 201 GLU A CA  
1354 C C   A GLU A 174 ? 0.59302 0.38905 0.31083 0.27302  -0.06568 -0.03155 201 GLU A C   
1355 C C   B GLU A 174 ? 0.59364 0.38969 0.31127 0.27342  -0.06585 -0.03168 201 GLU A C   
1356 O O   A GLU A 174 ? 0.61008 0.39067 0.32025 0.26672  -0.06635 -0.02796 201 GLU A O   
1357 O O   B GLU A 174 ? 0.60990 0.39109 0.32036 0.26703  -0.06644 -0.02806 201 GLU A O   
1358 C CB  A GLU A 174 ? 0.61264 0.43874 0.33999 0.29923  -0.07461 -0.04063 201 GLU A CB  
1359 C CB  B GLU A 174 ? 0.61322 0.43987 0.34057 0.29987  -0.07462 -0.04097 201 GLU A CB  
1360 C CG  A GLU A 174 ? 0.66664 0.52952 0.41793 0.30736  -0.07501 -0.04382 201 GLU A CG  
1361 C CG  B GLU A 174 ? 0.64005 0.50456 0.39134 0.30875  -0.07448 -0.04468 201 GLU A CG  
1362 C CD  A GLU A 174 ? 0.59812 0.48063 0.35824 0.31476  -0.07233 -0.04804 201 GLU A CD  
1363 C CD  B GLU A 174 ? 0.65007 0.53351 0.41909 0.30632  -0.07542 -0.04281 201 GLU A CD  
1364 O OE1 A GLU A 174 ? 0.70876 0.58909 0.46777 0.30820  -0.06681 -0.04653 201 GLU A OE1 
1365 O OE1 B GLU A 174 ? 0.60405 0.47094 0.36542 0.29835  -0.07631 -0.03869 201 GLU A OE1 
1366 O OE2 A GLU A 174 ? 0.83159 0.73150 0.59927 0.32796  -0.07614 -0.05337 201 GLU A OE2 
1367 O OE2 B GLU A 174 ? 0.71363 0.62825 0.50418 0.31254  -0.07538 -0.04569 201 GLU A OE2 
1368 N N   . THR A 175 ? 0.60717 0.38611 0.31190 0.27371  -0.06546 -0.03335 202 THR A N   
1369 C CA  A THR A 175 ? 0.62309 0.36638 0.30761 0.26470  -0.06495 -0.03058 202 THR A CA  
1370 C CA  B THR A 175 ? 0.62310 0.36635 0.30759 0.26468  -0.06496 -0.03056 202 THR A CA  
1371 C C   . THR A 175 ? 0.59238 0.34431 0.29245 0.24770  -0.05713 -0.02525 202 THR A C   
1372 O O   . THR A 175 ? 0.59759 0.32628 0.28593 0.23901  -0.05618 -0.02157 202 THR A O   
1373 C CB  A THR A 175 ? 0.69460 0.42091 0.36585 0.26821  -0.06637 -0.03399 202 THR A CB  
1374 C CB  B THR A 175 ? 0.69368 0.41941 0.36460 0.26810  -0.06640 -0.03393 202 THR A CB  
1375 O OG1 A THR A 175 ? 0.68701 0.44199 0.37922 0.26574  -0.06103 -0.03513 202 THR A OG1 
1376 O OG1 B THR A 175 ? 0.68488 0.40085 0.33993 0.28471  -0.07439 -0.03925 202 THR A OG1 
1377 C CG2 A THR A 175 ? 0.68632 0.40046 0.33961 0.28564  -0.07499 -0.03955 202 THR A CG2 
1378 C CG2 B THR A 175 ? 0.66142 0.34959 0.31299 0.25749  -0.06557 -0.03103 202 THR A CG2 
1379 N N   . GLN A 176 ? 0.55413 0.33854 0.27952 0.24306  -0.05150 -0.02490 203 GLN A N   
1380 C CA  . GLN A 176 ? 0.52217 0.31652 0.26351 0.22790  -0.04473 -0.02061 203 GLN A CA  
1381 C C   . GLN A 176 ? 0.57709 0.37777 0.32590 0.22256  -0.04398 -0.01672 203 GLN A C   
1382 O O   . GLN A 176 ? 0.50227 0.29113 0.24958 0.21123  -0.04082 -0.01310 203 GLN A O   
1383 C CB  . GLN A 176 ? 0.49148 0.31899 0.25617 0.22599  -0.03992 -0.02130 203 GLN A CB  
1384 C CG  . GLN A 176 ? 0.50018 0.32037 0.25819 0.22796  -0.03966 -0.02457 203 GLN A CG  
1385 C CD  . GLN A 176 ? 0.52913 0.34390 0.27345 0.24353  -0.04503 -0.02968 203 GLN A CD  
1386 O OE1 . GLN A 176 ? 0.53439 0.36294 0.28199 0.25358  -0.04766 -0.03129 203 GLN A OE1 
1387 N NE2 . GLN A 176 ? 0.61551 0.41037 0.34527 0.24585  -0.04709 -0.03276 203 GLN A NE2 
1388 N N   . ARG A 177 ? 0.50511 0.32637 0.26401 0.23035  -0.04666 -0.01771 204 ARG A N   
1389 C CA  . ARG A 177 ? 0.49514 0.32270 0.26115 0.22649  -0.04720 -0.01464 204 ARG A CA  
1390 C C   . ARG A 177 ? 0.52623 0.31695 0.26496 0.22636  -0.05098 -0.01321 204 ARG A C   
1391 O O   . ARG A 177 ? 0.51808 0.30244 0.25681 0.21693  -0.04856 -0.00930 204 ARG A O   
1392 C CB  . ARG A 177 ? 0.50136 0.35410 0.28086 0.23667  -0.05090 -0.01711 204 ARG A CB  
1393 C CG  . ARG A 177 ? 0.61766 0.47853 0.40533 0.23475  -0.05311 -0.01493 204 ARG A CG  
1394 C CD  . ARG A 177 ? 0.66177 0.54659 0.46287 0.24593  -0.05740 -0.01850 204 ARG A CD  
1395 N NE  . ARG A 177 ? 0.69351 0.55760 0.47179 0.26078  -0.06564 -0.02314 204 ARG A NE  
1396 C CZ  . ARG A 177 ? 0.82070 0.69834 0.60479 0.27300  -0.07175 -0.02733 204 ARG A CZ  
1397 N NH1 . ARG A 177 ? 0.75881 0.67123 0.57170 0.27170  -0.07008 -0.02730 204 ARG A NH1 
1398 N NH2 . ARG A 177 ? 0.74922 0.60440 0.50978 0.28685  -0.08007 -0.03188 204 ARG A NH2 
1399 N N   . ALA A 178 ? 0.56472 0.32944 0.27840 0.23690  -0.05701 -0.01629 205 ALA A N   
1400 C CA  . ALA A 178 ? 0.59982 0.32618 0.28400 0.23682  -0.06067 -0.01460 205 ALA A CA  
1401 C C   . ALA A 178 ? 0.59967 0.30345 0.27479 0.22245  -0.05457 -0.01063 205 ALA A C   
1402 O O   . ALA A 178 ? 0.61210 0.29465 0.27298 0.21584  -0.05353 -0.00705 205 ALA A O   
1403 C CB  . ALA A 178 ? 0.64372 0.34463 0.30167 0.25078  -0.06863 -0.01882 205 ALA A CB  
1404 N N   . GLN A 179 ? 0.58734 0.29520 0.27038 0.21746  -0.05044 -0.01153 206 GLN A N   
1405 C CA  . GLN A 179 ? 0.58545 0.27491 0.26409 0.20341  -0.04452 -0.00865 206 GLN A CA  
1406 C C   . GLN A 179 ? 0.55210 0.25917 0.24980 0.19158  -0.03857 -0.00478 206 GLN A C   
1407 O O   . GLN A 179 ? 0.56095 0.24652 0.24760 0.18140  -0.03493 -0.00142 206 GLN A O   
1408 C CB  . GLN A 179 ? 0.57658 0.27162 0.26369 0.20177  -0.04243 -0.01150 206 GLN A CB  
1409 C CG  . GLN A 179 ? 0.67240 0.34829 0.35684 0.18751  -0.03692 -0.00983 206 GLN A CG  
1410 C CD  . GLN A 179 ? 0.74358 0.37512 0.39718 0.18417  -0.03790 -0.00827 206 GLN A CD  
1411 O OE1 . GLN A 179 ? 0.84456 0.45364 0.48228 0.18754  -0.04086 -0.01079 206 GLN A OE1 
1412 N NE2 . GLN A 179 ? 0.68993 0.30776 0.33410 0.17695  -0.03513 -0.00406 206 GLN A NE2 
1413 N N   . LEU A 180 ? 0.51563 0.26108 0.24137 0.19244  -0.03724 -0.00521 207 LEU A N   
1414 C CA  . LEU A 180 ? 0.48431 0.24758 0.22894 0.18206  -0.03254 -0.00182 207 LEU A CA  
1415 C C   . LEU A 180 ? 0.49841 0.24827 0.23044 0.18176  -0.03449 0.00093  207 LEU A C   
1416 O O   . LEU A 180 ? 0.52168 0.26150 0.25129 0.17132  -0.03024 0.00417  207 LEU A O   
1417 C CB  . LEU A 180 ? 0.44982 0.25497 0.22495 0.18342  -0.03140 -0.00264 207 LEU A CB  
1418 C CG  . LEU A 180 ? 0.41898 0.24419 0.21539 0.17271  -0.02720 0.00072  207 LEU A CG  
1419 C CD1 . LEU A 180 ? 0.47232 0.28870 0.27124 0.16104  -0.02181 0.00173  207 LEU A CD1 
1420 C CD2 . LEU A 180 ? 0.43806 0.30149 0.26151 0.17454  -0.02655 0.00002  207 LEU A CD2 
1421 N N   . VAL A 181 ? 0.51704 0.26596 0.24024 0.19350  -0.04108 -0.00074 208 VAL A N   
1422 C CA  . VAL A 181 ? 0.53380 0.26897 0.24319 0.19455  -0.04413 0.00130  208 VAL A CA  
1423 C C   . VAL A 181 ? 0.62972 0.32184 0.30742 0.18830  -0.04209 0.00387  208 VAL A C   
1424 O O   . VAL A 181 ? 0.57010 0.25152 0.24112 0.18024  -0.03899 0.00726  208 VAL A O   
1425 C CB  . VAL A 181 ? 0.55288 0.29181 0.25662 0.20960  -0.05271 -0.00206 208 VAL A CB  
1426 C CG1 . VAL A 181 ? 0.65837 0.37312 0.33910 0.21221  -0.05725 -0.00061 208 VAL A CG1 
1427 C CG2 . VAL A 181 ? 0.58790 0.37039 0.32499 0.21271  -0.05320 -0.00371 208 VAL A CG2 
1428 N N   . THR A 182 ? 0.59786 0.26401 0.25511 0.19126  -0.04337 0.00233  209 THR A N   
1429 C CA  . THR A 182 ? 0.63479 0.25790 0.26100 0.18388  -0.04069 0.00494  209 THR A CA  
1430 C C   . THR A 182 ? 0.61646 0.23759 0.25107 0.16683  -0.03101 0.00816  209 THR A C   
1431 O O   . THR A 182 ? 0.64255 0.23960 0.25935 0.15785  -0.02673 0.01153  209 THR A O   
1432 C CB  . THR A 182 ? 0.75225 0.35211 0.36025 0.18930  -0.04381 0.00239  209 THR A CB  
1433 O OG1 . THR A 182 ? 0.70521 0.30092 0.30017 0.20532  -0.05316 -0.00065 209 THR A OG1 
1434 C CG2 . THR A 182 ? 0.79358 0.35013 0.37308 0.17826  -0.03923 0.00538  209 THR A CG2 
1435 N N   . TRP A 183 ? 0.58145 0.22787 0.24283 0.16218  -0.02732 0.00679  210 TRP A N   
1436 C CA  . TRP A 183 ? 0.56182 0.20963 0.23474 0.14670  -0.01876 0.00876  210 TRP A CA  
1437 C C   . TRP A 183 ? 0.54409 0.20386 0.22507 0.14171  -0.01621 0.01179  210 TRP A C   
1438 O O   . TRP A 183 ? 0.57483 0.21543 0.24523 0.12982  -0.00964 0.01438  210 TRP A O   
1439 C CB  . TRP A 183 ? 0.52631 0.20243 0.22812 0.14475  -0.01693 0.00596  210 TRP A CB  
1440 C CG  . TRP A 183 ? 0.59534 0.25393 0.28881 0.14445  -0.01713 0.00289  210 TRP A CG  
1441 C CD1 . TRP A 183 ? 0.64164 0.26159 0.30900 0.13979  -0.01586 0.00316  210 TRP A CD1 
1442 C CD2 . TRP A 183 ? 0.53884 0.21759 0.24986 0.14862  -0.01875 -0.00110 210 TRP A CD2 
1443 N NE1 . TRP A 183 ? 0.65083 0.26681 0.32067 0.14098  -0.01717 -0.00081 210 TRP A NE1 
1444 C CE2 . TRP A 183 ? 0.60515 0.25641 0.30050 0.14694  -0.01912 -0.00356 210 TRP A CE2 
1445 C CE3 . TRP A 183 ? 0.54941 0.26613 0.28680 0.15319  -0.01972 -0.00283 210 TRP A CE3 
1446 C CZ2 . TRP A 183 ? 0.59123 0.25206 0.29653 0.15054  -0.02102 -0.00813 210 TRP A CZ2 
1447 C CZ3 . TRP A 183 ? 0.54529 0.27066 0.29054 0.15641  -0.02088 -0.00688 210 TRP A CZ3 
1448 C CH2 . TRP A 183 ? 0.59019 0.28785 0.31932 0.15563  -0.02188 -0.00969 210 TRP A CH2 
1449 N N   . LEU A 184 ? 0.51857 0.21031 0.21894 0.14979  -0.02080 0.01121  211 LEU A N   
1450 C CA  . LEU A 184 ? 0.52002 0.22529 0.23042 0.14543  -0.01934 0.01374  211 LEU A CA  
1451 C C   . LEU A 184 ? 0.56506 0.23893 0.24518 0.14490  -0.01992 0.01614  211 LEU A C   
1452 O O   . LEU A 184 ? 0.55265 0.21994 0.22946 0.13556  -0.01485 0.01880  211 LEU A O   
1453 C CB  . LEU A 184 ? 0.47140 0.21487 0.20735 0.15392  -0.02477 0.01237  211 LEU A CB  
1454 C CG  . LEU A 184 ? 0.50930 0.28719 0.27696 0.15223  -0.02284 0.01069  211 LEU A CG  
1455 C CD1 . LEU A 184 ? 0.48440 0.29676 0.27458 0.15925  -0.02726 0.00953  211 LEU A CD1 
1456 C CD2 . LEU A 184 ? 0.49921 0.28467 0.28165 0.13981  -0.01646 0.01244  211 LEU A CD2 
1457 N N   . LYS A 185 ? 0.57093 0.22523 0.22807 0.15533  -0.02629 0.01492  212 LYS A N   
1458 C CA  . LYS A 185 ? 0.60986 0.23194 0.23527 0.15567  -0.02754 0.01694  212 LYS A CA  
1459 C C   . LYS A 185 ? 0.66190 0.24845 0.26379 0.14124  -0.01827 0.01987  212 LYS A C   
1460 O O   . LYS A 185 ? 0.69350 0.25776 0.27376 0.13617  -0.01547 0.02239  212 LYS A O   
1461 C CB  . LYS A 185 ? 0.67348 0.27956 0.27791 0.17024  -0.03681 0.01449  212 LYS A CB  
1462 C CG  . LYS A 185 ? 0.62920 0.26526 0.25137 0.18378  -0.04582 0.01152  212 LYS A CG  
1463 C CD  . LYS A 185 ? 0.76606 0.38142 0.36379 0.19851  -0.05522 0.00846  212 LYS A CD  
1464 C CE  . LYS A 185 ? 0.81340 0.46112 0.43220 0.21234  -0.06384 0.00419  212 LYS A CE  
1465 N NZ  . LYS A 185 ? 0.86126 0.48901 0.45624 0.22810  -0.07401 0.00031  212 LYS A NZ  
1466 N N   . GLY A 186 ? 0.63316 0.21407 0.23910 0.13380  -0.01302 0.01926  213 GLY A N   
1467 C CA  . GLY A 186 ? 0.69673 0.24634 0.28427 0.11819  -0.00318 0.02127  213 GLY A CA  
1468 C C   . GLY A 186 ? 0.66208 0.22552 0.26993 0.10297  0.00677  0.02198  213 GLY A C   
1469 O O   . GLY A 186 ? 0.65729 0.20181 0.25875 0.08816  0.01619  0.02202  213 GLY A O   
1470 N N   . ASN A 187 ? 0.58831 0.18552 0.22257 0.10564  0.00505  0.02189  214 ASN A N   
1471 C CA  . ASN A 187 ? 0.58746 0.19739 0.24092 0.09192  0.01390  0.02204  214 ASN A CA  
1472 C C   . ASN A 187 ? 0.59509 0.17665 0.22518 0.07798  0.02371  0.02421  214 ASN A C   
1473 O O   . ASN A 187 ? 0.62089 0.18471 0.22626 0.08213  0.02140  0.02642  214 ASN A O   
1474 C CB  . ASN A 187 ? 0.52972 0.17741 0.21104 0.09821  0.00925  0.02219  214 ASN A CB  
1475 C CG  . ASN A 187 ? 0.54304 0.20310 0.24360 0.08538  0.01739  0.02194  214 ASN A CG  
1476 O OD1 . ASN A 187 ? 0.53775 0.19353 0.24633 0.07465  0.02435  0.01946  214 ASN A OD1 
1477 N ND2 . ASN A 187 ? 0.49979 0.17582 0.20938 0.08611  0.01629  0.02360  214 ASN A ND2 
1478 N N   . THR A 188 ? 0.60330 0.18218 0.24264 0.06094  0.03503  0.02262  215 THR A N   
1479 C CA  . THR A 188 ? 0.62712 0.18281 0.24758 0.04489  0.04698  0.02349  215 THR A CA  
1480 C C   . THR A 188 ? 0.58590 0.16076 0.22349 0.03685  0.05302  0.02304  215 THR A C   
1481 O O   . THR A 188 ? 0.61083 0.16975 0.23290 0.02456  0.06300  0.02333  215 THR A O   
1482 C CB  . THR A 188 ? 0.62640 0.16462 0.24471 0.02839  0.05747  0.02044  215 THR A CB  
1483 O OG1 . THR A 188 ? 0.59249 0.15675 0.24645 0.01866  0.06246  0.01541  215 THR A OG1 
1484 C CG2 . THR A 188 ? 0.72927 0.25003 0.33388 0.03672  0.05059  0.02052  215 THR A CG2 
1485 N N   . THR A 189 ? 0.55087 0.15906 0.21909 0.04346  0.04745  0.02211  216 THR A N   
1486 C CA  . THR A 189 ? 0.56229 0.18856 0.25002 0.03420  0.05377  0.02069  216 THR A CA  
1487 C C   . THR A 189 ? 0.51903 0.15689 0.20482 0.04461  0.04662  0.02436  216 THR A C   
1488 O O   . THR A 189 ? 0.54380 0.19785 0.24615 0.03907  0.05008  0.02361  216 THR A O   
1489 C CB  . THR A 189 ? 0.55907 0.21510 0.28503 0.03259  0.05299  0.01603  216 THR A CB  
1490 O OG1 . THR A 189 ? 0.50083 0.18003 0.24079 0.05077  0.03989  0.01797  216 THR A OG1 
1491 C CG2 . THR A 189 ? 0.54263 0.19281 0.27654 0.02297  0.05806  0.01064  216 THR A CG2 
1492 N N   . GLY A 190 ? 0.55574 0.18791 0.22472 0.05944  0.03614  0.02718  217 GLY A N   
1493 C CA  . GLY A 190 ? 0.57146 0.22428 0.24881 0.07091  0.02661  0.02895  217 GLY A CA  
1494 C C   . GLY A 190 ? 0.53779 0.17134 0.18844 0.07076  0.02690  0.03089  217 GLY A C   
1495 O O   . GLY A 190 ? 0.59538 0.24586 0.25297 0.08082  0.01764  0.03167  217 GLY A O   
1496 N N   . ALA A 191 ? 0.58368 0.18414 0.20589 0.05874  0.03758  0.03112  218 ALA A N   
1497 C CA  . ALA A 191 ? 0.60443 0.18241 0.19669 0.06102  0.03644  0.03277  218 ALA A CA  
1498 C C   . ALA A 191 ? 0.61833 0.21291 0.21959 0.06055  0.03543  0.03340  218 ALA A C   
1499 O O   . ALA A 191 ? 0.71410 0.30207 0.30001 0.06929  0.02801  0.03448  218 ALA A O   
1500 C CB  . ALA A 191 ? 0.65280 0.19328 0.21405 0.04632  0.04979  0.03259  218 ALA A CB  
1501 N N   . ALA A 192 ? 0.55436 0.16973 0.17974 0.05083  0.04220  0.03238  219 ALA A N   
1502 C CA  . ALA A 192 ? 0.56728 0.19568 0.19815 0.04856  0.04258  0.03279  219 ALA A CA  
1503 C C   . ALA A 192 ? 0.56889 0.23482 0.23106 0.06081  0.02964  0.03339  219 ALA A C   
1504 O O   . ALA A 192 ? 0.53414 0.21447 0.20344 0.06009  0.02804  0.03363  219 ALA A O   
1505 C CB  . ALA A 192 ? 0.57282 0.19993 0.20879 0.02800  0.05988  0.03013  219 ALA A CB  
1506 N N   . SER A 193 ? 0.52546 0.20836 0.20585 0.07197  0.02023  0.03307  220 SER A N   
1507 C CA  . SER A 193 ? 0.46402 0.18626 0.17897 0.08162  0.00940  0.03264  220 SER A CA  
1508 C C   . SER A 193 ? 0.44952 0.18156 0.16425 0.09653  -0.00433 0.03194  220 SER A C   
1509 O O   . SER A 193 ? 0.48800 0.20440 0.18100 0.09886  -0.00689 0.03234  220 SER A O   
1510 C CB  . SER A 193 ? 0.43242 0.17160 0.17320 0.08060  0.01104  0.03138  220 SER A CB  
1511 O OG  . SER A 193 ? 0.47517 0.20642 0.21982 0.06596  0.02373  0.03066  220 SER A OG  
1512 N N   . ILE A 194 ? 0.42550 0.18279 0.16382 0.10563  -0.01232 0.03028  221 ILE A N   
1513 C CA  . ILE A 194 ? 0.43623 0.20581 0.17834 0.11763  -0.02386 0.02860  221 ILE A CA  
1514 C C   . ILE A 194 ? 0.50556 0.23898 0.20961 0.12248  -0.02534 0.02883  221 ILE A C   
1515 O O   . ILE A 194 ? 0.52283 0.25550 0.21934 0.12929  -0.03297 0.02793  221 ILE A O   
1516 C CB  . ILE A 194 ? 0.40840 0.20541 0.17730 0.12396  -0.02868 0.02653  221 ILE A CB  
1517 C CG1 . ILE A 194 ? 0.41078 0.24774 0.21903 0.12015  -0.02990 0.02598  221 ILE A CG1 
1518 C CG2 . ILE A 194 ? 0.44275 0.24027 0.20547 0.13588  -0.03825 0.02443  221 ILE A CG2 
1519 C CD1 . ILE A 194 ? 0.36750 0.23015 0.20188 0.12250  -0.03107 0.02435  221 ILE A CD1 
1520 N N   . ARG A 195 ? 0.51609 0.21835 0.19552 0.11882  -0.01839 0.02972  222 ARG A N   
1521 C CA  . ARG A 195 ? 0.56665 0.23236 0.20868 0.12347  -0.01996 0.02989  222 ARG A CA  
1522 C C   . ARG A 195 ? 0.62152 0.26742 0.23992 0.12047  -0.01866 0.03122  222 ARG A C   
1523 O O   . ARG A 195 ? 0.62757 0.25474 0.22270 0.12891  -0.02529 0.03064  222 ARG A O   
1524 C CB  . ARG A 195 ? 0.65518 0.29024 0.27568 0.11615  -0.01071 0.03082  222 ARG A CB  
1525 C CG  . ARG A 195 ? 0.75173 0.39931 0.38765 0.12176  -0.01365 0.02905  222 ARG A CG  
1526 C CD  . ARG A 195 ? 0.69221 0.31072 0.30937 0.11225  -0.00391 0.02977  222 ARG A CD  
1527 N NE  . ARG A 195 ? 0.66015 0.29282 0.29514 0.11536  -0.00531 0.02802  222 ARG A NE  
1528 C CZ  . ARG A 195 ? 0.83092 0.44784 0.45107 0.12266  -0.00931 0.02679  222 ARG A CZ  
1529 N NH1 . ARG A 195 ? 0.86201 0.44825 0.44934 0.12832  -0.01304 0.02714  222 ARG A NH1 
1530 N NH2 . ARG A 195 ? 0.70197 0.33275 0.33921 0.12455  -0.00981 0.02498  222 ARG A NH2 
1531 N N   . ALA A 196 ? 0.56149 0.21110 0.18496 0.10893  -0.01040 0.03264  223 ALA A N   
1532 C CA  . ALA A 196 ? 0.60446 0.23313 0.20300 0.10445  -0.00716 0.03377  223 ALA A CA  
1533 C C   . ALA A 196 ? 0.62854 0.27506 0.23495 0.11549  -0.01996 0.03233  223 ALA A C   
1534 O O   . ALA A 196 ? 0.69339 0.31887 0.27419 0.11601  -0.02051 0.03279  223 ALA A O   
1535 C CB  . ALA A 196 ? 0.61565 0.24512 0.21870 0.08802  0.00642  0.03481  223 ALA A CB  
1536 N N   . GLY A 197 ? 0.60060 0.28536 0.24205 0.12335  -0.02972 0.03026  224 GLY A N   
1537 C CA  . GLY A 197 ? 0.60390 0.30877 0.25729 0.13231  -0.04167 0.02794  224 GLY A CA  
1538 C C   . GLY A 197 ? 0.61600 0.31964 0.26493 0.14605  -0.05279 0.02529  224 GLY A C   
1539 O O   . GLY A 197 ? 0.66293 0.38283 0.32207 0.15357  -0.06307 0.02261  224 GLY A O   
1540 N N   . LEU A 198 ? 0.66806 0.35043 0.29965 0.14948  -0.05118 0.02554  225 LEU A N   
1541 C CA  . LEU A 198 ? 0.64730 0.32981 0.27608 0.16310  -0.06162 0.02248  225 LEU A CA  
1542 C C   . LEU A 198 ? 0.71003 0.34722 0.29323 0.16869  -0.06332 0.02282  225 LEU A C   
1543 O O   . LEU A 198 ? 0.76829 0.37178 0.32263 0.16028  -0.05355 0.02593  225 LEU A O   
1544 C CB  . LEU A 198 ? 0.63772 0.33441 0.28455 0.16483  -0.06033 0.02165  225 LEU A CB  
1545 C CG  . LEU A 198 ? 0.61646 0.35715 0.30800 0.16004  -0.05875 0.02124  225 LEU A CG  
1546 C CD1 . LEU A 198 ? 0.59934 0.34735 0.30112 0.16330  -0.05774 0.02013  225 LEU A CD1 
1547 C CD2 . LEU A 198 ? 0.58089 0.35470 0.29948 0.16475  -0.06788 0.01863  225 LEU A CD2 
1548 N N   . PRO A 199 ? 0.77017 0.40517 0.34610 0.18240  -0.07536 0.01940  226 PRO A N   
1549 C CA  . PRO A 199 ? 0.86877 0.45927 0.40025 0.18950  -0.07841 0.01934  226 PRO A CA  
1550 C C   . PRO A 199 ? 1.00401 0.56708 0.51534 0.18517  -0.07039 0.02152  226 PRO A C   
1551 O O   . PRO A 199 ? 0.87458 0.45573 0.40669 0.18600  -0.06965 0.02051  226 PRO A O   
1552 C CB  . PRO A 199 ? 0.91461 0.51814 0.45336 0.20602  -0.09343 0.01407  226 PRO A CB  
1553 C CG  . PRO A 199 ? 0.82479 0.47483 0.40586 0.20564  -0.09796 0.01181  226 PRO A CG  
1554 C CD  . PRO A 199 ? 0.70162 0.37502 0.31062 0.19163  -0.08649 0.01509  226 PRO A CD  
1555 N N   . THR A 200 ? 1.02287 0.54102 0.49248 0.18009  -0.06416 0.02444  227 THR A N   
1556 C CA  . THR A 200 ? 1.03053 0.52022 0.47977 0.17230  -0.05450 0.02690  227 THR A CA  
1557 C C   . THR A 200 ? 1.05442 0.53365 0.49399 0.18442  -0.06258 0.02426  227 THR A C   
1558 O O   . THR A 200 ? 1.18381 0.64607 0.61313 0.17893  -0.05601 0.02563  227 THR A O   
1559 C CB  . THR A 200 ? 1.15777 0.60105 0.56369 0.16281  -0.04529 0.03053  227 THR A CB  
1560 O OG1 . THR A 200 ? 1.20456 0.62326 0.58030 0.17437  -0.05513 0.02939  227 THR A OG1 
1561 C CG2 . THR A 200 ? 1.17186 0.62478 0.58815 0.14746  -0.03356 0.03316  227 THR A CG2 
1562 N N   . SER A 201 ? 0.98386 0.47327 0.42701 0.20051  -0.07667 0.02009  228 SER A N   
1563 C CA  . SER A 201 ? 1.12734 0.60919 0.56282 0.21318  -0.08510 0.01675  228 SER A CA  
1564 C C   . SER A 201 ? 1.00483 0.52953 0.48252 0.21587  -0.08664 0.01407  228 SER A C   
1565 O O   . SER A 201 ? 1.00963 0.52938 0.48289 0.22468  -0.09154 0.01144  228 SER A O   
1566 C CB  . SER A 201 ? 1.05383 0.52478 0.47168 0.23005  -0.09992 0.01258  228 SER A CB  
1567 O OG  . SER A 201 ? 1.09532 0.60985 0.55003 0.23714  -0.10836 0.00859  228 SER A OG  
1568 N N   . TRP A 202 ? 0.96526 0.53061 0.48230 0.20869  -0.08267 0.01461  229 TRP A N   
1569 C CA  . TRP A 202 ? 0.92754 0.53326 0.48427 0.20994  -0.08295 0.01250  229 TRP A CA  
1570 C C   . TRP A 202 ? 0.90923 0.50760 0.46620 0.20016  -0.07246 0.01505  229 TRP A C   
1571 O O   . TRP A 202 ? 0.87599 0.45572 0.42015 0.18723  -0.06222 0.01898  229 TRP A O   
1572 C CB  . TRP A 202 ? 0.88177 0.53086 0.47839 0.20488  -0.08238 0.01247  229 TRP A CB  
1573 C CG  . TRP A 202 ? 0.81169 0.47517 0.41548 0.21452  -0.09351 0.00908  229 TRP A CG  
1574 C CD1 . TRP A 202 ? 0.97085 0.60997 0.54661 0.22690  -0.10363 0.00621  229 TRP A CD1 
1575 C CD2 . TRP A 202 ? 0.81201 0.51685 0.45322 0.21251  -0.09622 0.00784  229 TRP A CD2 
1576 N NE1 . TRP A 202 ? 0.82760 0.49159 0.42219 0.23295  -0.11263 0.00287  229 TRP A NE1 
1577 C CE2 . TRP A 202 ? 0.91165 0.61604 0.54662 0.22372  -0.10801 0.00397  229 TRP A CE2 
1578 C CE3 . TRP A 202 ? 0.79899 0.54001 0.47768 0.20213  -0.09013 0.00949  229 TRP A CE3 
1579 C CZ2 . TRP A 202 ? 0.79208 0.53148 0.45800 0.22403  -0.11345 0.00172  229 TRP A CZ2 
1580 C CZ3 . TRP A 202 ? 0.66849 0.44333 0.37703 0.20226  -0.09538 0.00766  229 TRP A CZ3 
1581 C CH2 . TRP A 202 ? 0.74807 0.52197 0.45037 0.21276  -0.10675 0.00383  229 TRP A CH2 
1582 N N   . THR A 203 ? 0.81716 0.42925 0.38775 0.20645  -0.07502 0.01238  230 THR A N   
1583 C CA  . THR A 203 ? 0.73068 0.33994 0.30522 0.19842  -0.06642 0.01397  230 THR A CA  
1584 C C   . THR A 203 ? 0.68945 0.34225 0.30711 0.19097  -0.06133 0.01438  230 THR A C   
1585 O O   . THR A 203 ? 0.65776 0.34644 0.30503 0.19687  -0.06672 0.01180  230 THR A O   
1586 C CB  . THR A 203 ? 0.77128 0.37091 0.33607 0.20931  -0.07189 0.01071  230 THR A CB  
1587 O OG1 . THR A 203 ? 0.92566 0.48243 0.44832 0.21623  -0.07725 0.01045  230 THR A OG1 
1588 C CG2 . THR A 203 ? 0.79612 0.39087 0.36344 0.20099  -0.06354 0.01213  230 THR A CG2 
1589 N N   . VAL A 204 ? 0.67778 0.32641 0.29825 0.17749  -0.05087 0.01753  231 VAL A N   
1590 C CA  . VAL A 204 ? 0.59881 0.28426 0.25667 0.16958  -0.04576 0.01817  231 VAL A CA  
1591 C C   . VAL A 204 ? 0.60784 0.28968 0.26916 0.16365  -0.03894 0.01844  231 VAL A C   
1592 O O   . VAL A 204 ? 0.66898 0.31626 0.30309 0.15816  -0.03383 0.01999  231 VAL A O   
1593 C CB  . VAL A 204 ? 0.63044 0.31706 0.29105 0.15860  -0.04019 0.02121  231 VAL A CB  
1594 C CG1 . VAL A 204 ? 0.53940 0.26234 0.23737 0.15099  -0.03577 0.02169  231 VAL A CG1 
1595 C CG2 . VAL A 204 ? 0.73361 0.42143 0.38843 0.16494  -0.04768 0.02061  231 VAL A CG2 
1596 N N   . GLY A 205 ? 0.52317 0.24006 0.21764 0.16389  -0.03855 0.01690  232 GLY A N   
1597 C CA  . GLY A 205 ? 0.50955 0.22764 0.21200 0.15696  -0.03186 0.01705  232 GLY A CA  
1598 C C   . GLY A 205 ? 0.48039 0.23060 0.21512 0.14845  -0.02761 0.01815  232 GLY A C   
1599 O O   . GLY A 205 ? 0.50837 0.29045 0.26773 0.15211  -0.03181 0.01725  232 GLY A O   
1600 N N   . ASP A 206 ? 0.47501 0.21727 0.21047 0.13682  -0.01952 0.01986  233 ASP A N   
1601 C CA  . ASP A 206 ? 0.44575 0.21597 0.20942 0.12952  -0.01648 0.02076  233 ASP A CA  
1602 C C   . ASP A 206 ? 0.47409 0.24209 0.24559 0.12014  -0.00903 0.02045  233 ASP A C   
1603 O O   . ASP A 206 ? 0.46600 0.20662 0.21835 0.11674  -0.00506 0.02003  233 ASP A O   
1604 C CB  . ASP A 206 ? 0.44284 0.20489 0.19794 0.12440  -0.01509 0.02322  233 ASP A CB  
1605 C CG  . ASP A 206 ? 0.47530 0.20463 0.20793 0.11255  -0.00552 0.02508  233 ASP A CG  
1606 O OD1 . ASP A 206 ? 0.51557 0.21164 0.21880 0.11181  -0.00329 0.02541  233 ASP A OD1 
1607 O OD2 . ASP A 206 ? 0.46126 0.19724 0.20574 0.10270  0.00070  0.02590  233 ASP A OD2 
1608 N N   . LYS A 207 ? 0.36763 0.16456 0.16824 0.11551  -0.00747 0.02025  234 LYS A N   
1609 C CA  . LYS A 207 ? 0.35423 0.15004 0.16468 0.10613  -0.00072 0.01918  234 LYS A CA  
1610 C C   . LYS A 207 ? 0.33235 0.14074 0.15757 0.09903  0.00207  0.02034  234 LYS A C   
1611 O O   . LYS A 207 ? 0.34465 0.18412 0.19269 0.10203  -0.00265 0.02075  234 LYS A O   
1612 C CB  . LYS A 207 ? 0.32979 0.15048 0.16330 0.10892  -0.00245 0.01645  234 LYS A CB  
1613 C CG  . LYS A 207 ? 0.32081 0.14118 0.16647 0.09952  0.00351  0.01394  234 LYS A CG  
1614 C CD  . LYS A 207 ? 0.38157 0.16640 0.20528 0.09377  0.00877  0.01176  234 LYS A CD  
1615 C CE  . LYS A 207 ? 0.35964 0.14344 0.19774 0.08139  0.01569  0.00703  234 LYS A CE  
1616 N NZ  . LYS A 207 ? 0.38586 0.15551 0.21719 0.07039  0.02295  0.00770  234 LYS A NZ  
1617 N N   . THR A 208 ? 0.36068 0.14526 0.17425 0.08808  0.01054  0.02020  235 THR A N   
1618 C CA  . THR A 208 ? 0.34129 0.13464 0.16822 0.08065  0.01459  0.02007  235 THR A CA  
1619 C C   . THR A 208 ? 0.33272 0.14661 0.18891 0.07624  0.01705  0.01547  235 THR A C   
1620 O O   . THR A 208 ? 0.33972 0.15754 0.20322 0.07708  0.01667  0.01241  235 THR A O   
1621 C CB  . THR A 208 ? 0.40696 0.16572 0.20944 0.06761  0.02526  0.02000  235 THR A CB  
1622 O OG1 . THR A 208 ? 0.43726 0.17642 0.23273 0.05845  0.03259  0.01609  235 THR A OG1 
1623 C CG2 . THR A 208 ? 0.43793 0.17661 0.20962 0.07215  0.02241  0.02435  235 THR A CG2 
1624 N N   . GLY A 209 ? 0.30381 0.14048 0.18145 0.06801  0.01852  0.01319  236 GLY A N   
1625 C CA  . GLY A 209 ? 0.31384 0.17421 0.22116 0.05895  0.02089  0.00666  236 GLY A CA  
1626 C C   . GLY A 209 ? 0.32581 0.19988 0.24788 0.04608  0.02498  0.00271  236 GLY A C   
1627 O O   . GLY A 209 ? 0.31313 0.19028 0.23048 0.04749  0.02291  0.00595  236 GLY A O   
1628 N N   . SER A 210 ? 0.30452 0.18621 0.24412 0.03387  0.03043  -0.00531 237 SER A N   
1629 C CA  . SER A 210 ? 0.23831 0.13478 0.19443 0.02213  0.03430  -0.01085 237 SER A CA  
1630 C C   . SER A 210 ? 0.27560 0.19345 0.26132 0.01592  0.03372  -0.01931 237 SER A C   
1631 O O   . SER A 210 ? 0.27310 0.18724 0.26153 0.01708  0.03324  -0.02210 237 SER A O   
1632 C CB  . SER A 210 ? 0.37976 0.25254 0.31642 0.00980  0.04557  -0.01341 237 SER A CB  
1633 O OG  . SER A 210 ? 0.41748 0.27219 0.34832 0.00106  0.05339  -0.01848 237 SER A OG  
1634 N N   . GLY A 211 ? 0.26095 0.20076 0.26813 0.01067  0.03240  -0.02361 238 GLY A N   
1635 C CA  . GLY A 211 ? 0.21947 0.17979 0.25451 0.00668  0.02960  -0.03167 238 GLY A CA  
1636 C C   . GLY A 211 ? 0.26817 0.24689 0.32268 -0.00051 0.02966  -0.03775 238 GLY A C   
1637 O O   . GLY A 211 ? 0.23553 0.20940 0.28120 -0.00475 0.03421  -0.03728 238 GLY A O   
1638 N N   . ASP A 212 ? 0.19179 0.19075 0.27173 -0.00108 0.02391  -0.04388 239 ASP A N   
1639 C CA  . ASP A 212 ? 0.21083 0.22787 0.31115 -0.00648 0.02225  -0.05074 239 ASP A CA  
1640 C C   . ASP A 212 ? 0.19367 0.21914 0.29238 -0.00020 0.01615  -0.04281 239 ASP A C   
1641 O O   . ASP A 212 ? 0.19499 0.21513 0.27981 0.00844  0.01275  -0.03258 239 ASP A O   
1642 C CB  . ASP A 212 ? 0.17865 0.21305 0.30417 -0.00611 0.01502  -0.05826 239 ASP A CB  
1643 C CG  . ASP A 212 ? 0.38733 0.41724 0.51837 -0.01350 0.02064  -0.06886 239 ASP A CG  
1644 O OD1 . ASP A 212 ? 0.35189 0.36730 0.47063 -0.02171 0.03138  -0.07101 239 ASP A OD1 
1645 O OD2 . ASP A 212 ? 0.42053 0.45589 0.55658 -0.00763 0.01434  -0.07105 239 ASP A OD2 
1646 N N   . TYR A 213 ? 0.15719 0.19643 0.27134 -0.00442 0.01435  -0.04865 240 TYR A N   
1647 C CA  . TYR A 213 ? 0.20056 0.24696 0.31389 -0.00008 0.00864  -0.04296 240 TYR A CA  
1648 C C   . TYR A 213 ? 0.17051 0.19946 0.25683 0.00180  0.01346  -0.03602 240 TYR A C   
1649 O O   . TYR A 213 ? 0.18865 0.22031 0.26962 0.00903  0.00694  -0.02838 240 TYR A O   
1650 C CB  . TYR A 213 ? 0.15648 0.20711 0.26569 0.00744  -0.00271 -0.03235 240 TYR A CB  
1651 C CG  . TYR A 213 ? 0.16327 0.21071 0.26830 0.00440  -0.00654 -0.03373 240 TYR A CG  
1652 C CD1 . TYR A 213 ? 0.18973 0.23350 0.29516 0.00420  -0.00686 -0.03628 240 TYR A CD1 
1653 C CD2 . TYR A 213 ? 0.23897 0.28643 0.34073 0.00334  -0.00908 -0.03341 240 TYR A CD2 
1654 C CE1 . TYR A 213 ? 0.22517 0.26544 0.32826 0.00375  -0.00963 -0.03863 240 TYR A CE1 
1655 C CE2 . TYR A 213 ? 0.26844 0.31145 0.37150 0.00330  -0.01150 -0.03792 240 TYR A CE2 
1656 C CZ  . TYR A 213 ? 0.25224 0.29170 0.35717 0.00389  -0.01186 -0.04121 240 TYR A CZ  
1657 O OH  . TYR A 213 ? 0.27338 0.30871 0.38250 0.00545  -0.01492 -0.04721 240 TYR A OH  
1658 N N   . GLY A 214 ? 0.20383 0.21420 0.27298 -0.00504 0.02466  -0.03913 241 GLY A N   
1659 C CA  . GLY A 214 ? 0.21052 0.19988 0.24978 -0.00335 0.02930  -0.03270 241 GLY A CA  
1660 C C   . GLY A 214 ? 0.23290 0.21411 0.25718 0.00880  0.02266  -0.02153 241 GLY A C   
1661 O O   . GLY A 214 ? 0.23296 0.20331 0.23713 0.01460  0.02058  -0.01518 241 GLY A O   
1662 N N   . THR A 215 ? 0.17962 0.16584 0.21264 0.01364  0.01893  -0.01957 242 THR A N   
1663 C CA  . THR A 215 ? 0.16532 0.14843 0.18816 0.02605  0.01250  -0.01016 242 THR A CA  
1664 C C   . THR A 215 ? 0.20347 0.15705 0.19451 0.02819  0.01818  -0.00630 242 THR A C   
1665 O O   . THR A 215 ? 0.22695 0.16362 0.20866 0.02087  0.02669  -0.01029 242 THR A O   
1666 C CB  . THR A 215 ? 0.17923 0.17495 0.21833 0.03039  0.00823  -0.00988 242 THR A CB  
1667 O OG1 . THR A 215 ? 0.17032 0.19058 0.23563 0.02887  0.00199  -0.01223 242 THR A OG1 
1668 C CG2 . THR A 215 ? 0.18141 0.17472 0.21004 0.04356  0.00318  -0.00115 242 THR A CG2 
1669 N N   . THR A 216 ? 0.19599 0.14260 0.17040 0.03811  0.01292  0.00103  243 THR A N   
1670 C CA  . THR A 216 ? 0.19798 0.11300 0.13778 0.04120  0.01680  0.00515  243 THR A CA  
1671 C C   . THR A 216 ? 0.24369 0.16010 0.17667 0.05750  0.00692  0.01266  243 THR A C   
1672 O O   . THR A 216 ? 0.22945 0.16037 0.16894 0.06405  -0.00119 0.01543  243 THR A O   
1673 C CB  . THR A 216 ? 0.27954 0.18155 0.20124 0.03590  0.02066  0.00462  243 THR A CB  
1674 O OG1 . THR A 216 ? 0.28073 0.19136 0.21705 0.02159  0.02878  -0.00375 243 THR A OG1 
1675 C CG2 . THR A 216 ? 0.31896 0.18313 0.20153 0.03688  0.02638  0.00867  243 THR A CG2 
1676 N N   . ASN A 217 ? 0.22807 0.13018 0.14903 0.06416  0.00731  0.01504  244 ASN A N   
1677 C CA  . ASN A 217 ? 0.25386 0.16205 0.17354 0.08034  -0.00166 0.02044  244 ASN A CA  
1678 C C   . ASN A 217 ? 0.27446 0.15065 0.16091 0.08752  -0.00134 0.02357  244 ASN A C   
1679 O O   . ASN A 217 ? 0.29632 0.14238 0.16123 0.08092  0.00676  0.02249  244 ASN A O   
1680 C CB  . ASN A 217 ? 0.22639 0.15407 0.16789 0.08270  -0.00277 0.01904  244 ASN A CB  
1681 C CG  . ASN A 217 ? 0.23986 0.19754 0.21302 0.07614  -0.00395 0.01622  244 ASN A CG  
1682 O OD1 . ASN A 217 ? 0.20912 0.18127 0.19337 0.07369  -0.00741 0.01650  244 ASN A OD1 
1683 N ND2 . ASN A 217 ? 0.21248 0.17895 0.19952 0.07373  -0.00208 0.01328  244 ASN A ND2 
1684 N N   . ASP A 218 ? 0.25771 0.14724 0.14606 0.09435  -0.00885 0.02430  245 ASP A N   
1685 C CA  . ASP A 218 ? 0.28192 0.14833 0.14503 0.09983  -0.00930 0.02468  245 ASP A CA  
1686 C C   . ASP A 218 ? 0.34076 0.23192 0.21963 0.10677  -0.01640 0.02356  245 ASP A C   
1687 O O   . ASP A 218 ? 0.29170 0.20705 0.18949 0.10682  -0.02127 0.02353  245 ASP A O   
1688 C CB  . ASP A 218 ? 0.31605 0.15229 0.14716 0.10028  -0.00875 0.02665  245 ASP A CB  
1689 C CG  . ASP A 218 ? 0.37047 0.17418 0.17038 0.10346  -0.00721 0.02679  245 ASP A CG  
1690 O OD1 . ASP A 218 ? 0.35623 0.15622 0.15680 0.10432  -0.00536 0.02543  245 ASP A OD1 
1691 O OD2 . ASP A 218 ? 0.41819 0.19899 0.19191 0.10493  -0.00806 0.02798  245 ASP A OD2 
1692 N N   . ILE A 219 ? 0.30016 0.18539 0.17282 0.11136  -0.01624 0.02232  246 ILE A N   
1693 C CA  . ILE A 219 ? 0.30962 0.21309 0.19284 0.11830  -0.02164 0.02105  246 ILE A CA  
1694 C C   . ILE A 219 ? 0.35066 0.22776 0.20562 0.12696  -0.02395 0.02036  246 ILE A C   
1695 O O   . ILE A 219 ? 0.37748 0.22692 0.21050 0.12634  -0.02014 0.02042  246 ILE A O   
1696 C CB  . ILE A 219 ? 0.26555 0.19187 0.17126 0.11647  -0.01991 0.01966  246 ILE A CB  
1697 C CG1 . ILE A 219 ? 0.31031 0.21843 0.20253 0.11745  -0.01589 0.01833  246 ILE A CG1 
1698 C CG2 . ILE A 219 ? 0.24088 0.18926 0.17182 0.10693  -0.01793 0.02027  246 ILE A CG2 
1699 C CD1 . ILE A 219 ? 0.29714 0.22693 0.20890 0.11654  -0.01453 0.01661  246 ILE A CD1 
1700 N N   . ALA A 220 ? 0.33859 0.22224 0.19327 0.13455  -0.03040 0.01951  247 ALA A N   
1701 C CA  . ALA A 220 ? 0.36101 0.21668 0.18606 0.14343  -0.03380 0.01860  247 ALA A CA  
1702 C C   . ALA A 220 ? 0.42078 0.29093 0.25317 0.15377  -0.04047 0.01600  247 ALA A C   
1703 O O   . ALA A 220 ? 0.39599 0.29547 0.25377 0.15363  -0.04327 0.01549  247 ALA A O   
1704 C CB  . ALA A 220 ? 0.39854 0.23056 0.20016 0.14312  -0.03539 0.02017  247 ALA A CB  
1705 N N   A VAL A 221 ? 0.41790 0.26587 0.22743 0.16231  -0.04272 0.01425  248 VAL A N   
1706 N N   B VAL A 221 ? 0.41813 0.26602 0.22752 0.16238  -0.04281 0.01425  248 VAL A N   
1707 C CA  A VAL A 221 ? 0.41354 0.26514 0.22019 0.17449  -0.05026 0.01125  248 VAL A CA  
1708 C CA  B VAL A 221 ? 0.41281 0.26529 0.22022 0.17447  -0.05032 0.01124  248 VAL A CA  
1709 C C   A VAL A 221 ? 0.45278 0.27194 0.22698 0.18029  -0.05520 0.01124  248 VAL A C   
1710 C C   B VAL A 221 ? 0.45322 0.27252 0.22742 0.18071  -0.05534 0.01110  248 VAL A C   
1711 O O   A VAL A 221 ? 0.51870 0.30480 0.26533 0.17717  -0.05173 0.01293  248 VAL A O   
1712 O O   B VAL A 221 ? 0.51881 0.30474 0.26506 0.17816  -0.05205 0.01261  248 VAL A O   
1713 C CB  A VAL A 221 ? 0.45660 0.30685 0.26038 0.18136  -0.05013 0.00857  248 VAL A CB  
1714 C CB  B VAL A 221 ? 0.45462 0.30882 0.26202 0.18091  -0.04998 0.00858  248 VAL A CB  
1715 C CG1 A VAL A 221 ? 0.48354 0.34282 0.28900 0.19441  -0.05803 0.00484  248 VAL A CG1 
1716 C CG1 B VAL A 221 ? 0.44865 0.27168 0.23157 0.17847  -0.04558 0.00928  248 VAL A CG1 
1717 C CG2 A VAL A 221 ? 0.38806 0.26402 0.21803 0.17438  -0.04414 0.00897  248 VAL A CG2 
1718 C CG2 B VAL A 221 ? 0.48948 0.34290 0.28962 0.19496  -0.05827 0.00486  248 VAL A CG2 
1719 N N   . ILE A 222 ? 0.48128 0.30843 0.25784 0.18803  -0.06308 0.00934  249 ILE A N   
1720 C CA  . ILE A 222 ? 0.52279 0.32108 0.26967 0.19319  -0.06849 0.00927  249 ILE A CA  
1721 C C   . ILE A 222 ? 0.57412 0.36808 0.31134 0.20813  -0.07803 0.00494  249 ILE A C   
1722 O O   . ILE A 222 ? 0.56202 0.38643 0.32483 0.21319  -0.08226 0.00216  249 ILE A O   
1723 C CB  . ILE A 222 ? 0.55032 0.36079 0.30773 0.18817  -0.07018 0.01070  249 ILE A CB  
1724 C CG1 . ILE A 222 ? 0.54433 0.36314 0.31492 0.17400  -0.06127 0.01435  249 ILE A CG1 
1725 C CG2 . ILE A 222 ? 0.56221 0.33899 0.28448 0.19390  -0.07573 0.01050  249 ILE A CG2 
1726 C CD1 . ILE A 222 ? 0.53043 0.37486 0.32448 0.16875  -0.06314 0.01504  249 ILE A CD1 
1727 N N   . TRP A 223 ? 0.63627 0.39151 0.33616 0.21482  -0.08123 0.00430  250 TRP A N   
1728 C CA  . TRP A 223 ? 0.60381 0.34784 0.28788 0.23029  -0.09150 -0.00024 250 TRP A CA  
1729 C C   . TRP A 223 ? 0.69911 0.41734 0.35605 0.23464  -0.09801 -0.00027 250 TRP A C   
1730 O O   . TRP A 223 ? 0.70286 0.38028 0.32297 0.23362  -0.09656 0.00178  250 TRP A O   
1731 C CB  . TRP A 223 ? 0.63871 0.35569 0.29871 0.23544  -0.09091 -0.00132 250 TRP A CB  
1732 C CG  . TRP A 223 ? 0.72080 0.46072 0.40358 0.23436  -0.08649 -0.00245 250 TRP A CG  
1733 C CD1 . TRP A 223 ? 0.66851 0.42890 0.36604 0.24500  -0.09139 -0.00709 250 TRP A CD1 
1734 C CD2 . TRP A 223 ? 0.70322 0.44649 0.39498 0.22235  -0.07625 0.00073  250 TRP A CD2 
1735 N NE1 . TRP A 223 ? 0.67461 0.45076 0.38902 0.24016  -0.08444 -0.00672 250 TRP A NE1 
1736 C CE2 . TRP A 223 ? 0.70686 0.47265 0.41804 0.22650  -0.07557 -0.00207 250 TRP A CE2 
1737 C CE3 . TRP A 223 ? 0.67101 0.40034 0.35613 0.20866  -0.06763 0.00531  250 TRP A CE3 
1738 C CZ2 . TRP A 223 ? 0.64001 0.41385 0.36303 0.21786  -0.06732 -0.00048 250 TRP A CZ2 
1739 C CZ3 . TRP A 223 ? 0.67507 0.41338 0.37363 0.20017  -0.05966 0.00659  250 TRP A CZ3 
1740 C CH2 . TRP A 223 ? 0.63609 0.39587 0.35277 0.20499  -0.05992 0.00371  250 TRP A CH2 
1741 N N   . PRO A 224 ? 0.64661 0.57672 0.52179 0.29657  -0.16343 0.05242  251 PRO A N   
1742 C CA  . PRO A 224 ? 0.68428 0.62653 0.55021 0.30194  -0.17032 0.07150  251 PRO A CA  
1743 C C   . PRO A 224 ? 0.75353 0.68964 0.63565 0.31511  -0.18460 0.08272  251 PRO A C   
1744 O O   . PRO A 224 ? 0.75306 0.68398 0.64788 0.32390  -0.18857 0.06727  251 PRO A O   
1745 C CB  . PRO A 224 ? 0.74650 0.72237 0.59481 0.30649  -0.16681 0.05133  251 PRO A CB  
1746 C CG  . PRO A 224 ? 0.69625 0.67642 0.54818 0.29835  -0.15537 0.02844  251 PRO A CG  
1747 C CD  . PRO A 224 ? 0.61630 0.57254 0.48394 0.29870  -0.15675 0.02582  251 PRO A CD  
1748 N N   . GLN A 225 ? 0.87328 0.81175 0.75487 0.31721  -0.19264 0.11086  252 GLN A N   
1749 C CA  . GLN A 225 ? 1.02435 0.95972 0.92500 0.32958  -0.20742 0.12675  252 GLN A CA  
1750 C C   . GLN A 225 ? 0.90604 0.86604 0.79756 0.34408  -0.21256 0.10519  252 GLN A C   
1751 O O   . GLN A 225 ? 0.85412 0.84068 0.72279 0.34558  -0.21027 0.09582  252 GLN A O   
1752 C CB  . GLN A 225 ? 0.85512 0.79279 0.75673 0.32717  -0.21550 0.16532  252 GLN A CB  
1753 C CG  . GLN A 225 ? 1.03669 0.95277 0.95697 0.31176  -0.21275 0.19372  252 GLN A CG  
1754 C CD  . GLN A 225 ? 1.06791 0.95997 1.03699 0.31328  -0.21939 0.21207  252 GLN A CD  
1755 O OE1 . GLN A 225 ? 1.04874 0.94173 1.04136 0.32359  -0.23206 0.23269  252 GLN A OE1 
1756 N NE2 . GLN A 225 ? 1.20935 1.08140 1.19458 0.30520  -0.20943 0.20443  252 GLN A NE2 
1757 N N   . GLY A 226 ? 0.95705 0.90938 0.86906 0.35554  -0.21986 0.09681  253 GLY A N   
1758 C CA  . GLY A 226 ? 0.88433 0.86000 0.79488 0.36939  -0.22527 0.07879  253 GLY A CA  
1759 C C   . GLY A 226 ? 0.93792 0.94026 0.83170 0.36630  -0.21514 0.05147  253 GLY A C   
1760 O O   . GLY A 226 ? 0.85551 0.88566 0.74069 0.37103  -0.21886 0.04729  253 GLY A O   
1761 N N   . ARG A 227 ? 0.87054 0.86620 0.76344 0.35803  -0.20331 0.03420  254 ARG A N   
1762 C CA  . ARG A 227 ? 0.78955 0.81143 0.67535 0.35278  -0.19312 0.01300  254 ARG A CA  
1763 C C   . ARG A 227 ? 0.66556 0.67674 0.55600 0.34643  -0.18250 -0.00153 254 ARG A C   
1764 O O   . ARG A 227 ? 0.76342 0.74498 0.65484 0.34111  -0.18150 0.00560  254 ARG A O   
1765 C CB  . ARG A 227 ? 0.87425 0.90706 0.74215 0.34263  -0.18848 0.01812  254 ARG A CB  
1766 C CG  . ARG A 227 ? 0.77711 0.84196 0.64653 0.33953  -0.18329 -0.00140 254 ARG A CG  
1767 C CD  . ARG A 227 ? 0.71239 0.77570 0.57243 0.32521  -0.17195 -0.00489 254 ARG A CD  
1768 N NE  . ARG A 227 ? 0.70755 0.80281 0.57736 0.32167  -0.16985 -0.02186 254 ARG A NE  
1769 C CZ  . ARG A 227 ? 0.84582 0.95479 0.73619 0.31556  -0.16227 -0.03405 254 ARG A CZ  
1770 N NH1 . ARG A 227 ? 0.66722 0.76163 0.56325 0.31380  -0.15475 -0.03455 254 ARG A NH1 
1771 N NH2 . ARG A 227 ? 0.85664 0.99658 0.76476 0.31115  -0.16341 -0.04501 254 ARG A NH2 
1772 N N   . ALA A 228 ? 0.64154 0.67936 0.53810 0.34713  -0.17563 -0.01974 255 ALA A N   
1773 C CA  . ALA A 228 ? 0.67667 0.71183 0.57666 0.34372  -0.16611 -0.03266 255 ALA A CA  
1774 C C   . ALA A 228 ? 0.59854 0.61712 0.48927 0.32667  -0.15677 -0.02879 255 ALA A C   
1775 O O   . ALA A 228 ? 0.59409 0.61713 0.47775 0.31713  -0.15399 -0.02160 255 ALA A O   
1776 C CB  . ALA A 228 ? 0.62234 0.69702 0.53523 0.34560  -0.15908 -0.04569 255 ALA A CB  
1777 N N   . PRO A 229 ? 0.59453 0.59490 0.48475 0.32372  -0.15275 -0.03436 256 PRO A N   
1778 C CA  . PRO A 229 ? 0.57237 0.55663 0.45678 0.30702  -0.14436 -0.02950 256 PRO A CA  
1779 C C   . PRO A 229 ? 0.55153 0.56387 0.43788 0.29565  -0.13205 -0.03547 256 PRO A C   
1780 O O   . PRO A 229 ? 0.51951 0.56493 0.41638 0.29925  -0.12857 -0.04428 256 PRO A O   
1781 C CB  . PRO A 229 ? 0.58207 0.54453 0.46767 0.30954  -0.14593 -0.03751 256 PRO A CB  
1782 C CG  . PRO A 229 ? 0.69133 0.66866 0.58050 0.32826  -0.15169 -0.05161 256 PRO A CG  
1783 C CD  . PRO A 229 ? 0.61925 0.60706 0.51329 0.33717  -0.15917 -0.04409 256 PRO A CD  
1784 N N   . LEU A 230 ? 0.51526 0.51448 0.39646 0.28095  -0.12570 -0.02804 257 LEU A N   
1785 C CA  . LEU A 230 ? 0.47860 0.49914 0.36546 0.26842  -0.11495 -0.03178 257 LEU A CA  
1786 C C   . LEU A 230 ? 0.46131 0.46412 0.34789 0.25647  -0.10701 -0.03070 257 LEU A C   
1787 O O   . LEU A 230 ? 0.48118 0.45158 0.36184 0.25475  -0.11067 -0.02378 257 LEU A O   
1788 C CB  . LEU A 230 ? 0.47493 0.49984 0.35507 0.26309  -0.11549 -0.02494 257 LEU A CB  
1789 C CG  . LEU A 230 ? 0.50483 0.53896 0.37785 0.27493  -0.12621 -0.02194 257 LEU A CG  
1790 C CD1 . LEU A 230 ? 0.59849 0.62723 0.45562 0.27067  -0.12600 -0.01248 257 LEU A CD1 
1791 C CD2 . LEU A 230 ? 0.57152 0.64289 0.46089 0.27957  -0.12890 -0.03413 257 LEU A CD2 
1792 N N   . VAL A 231 ? 0.42878 0.45445 0.32691 0.24734  -0.09711 -0.03552 258 VAL A N   
1793 C CA  . VAL A 231 ? 0.40803 0.42168 0.30782 0.23412  -0.08887 -0.03302 258 VAL A CA  
1794 C C   . VAL A 231 ? 0.37898 0.40456 0.28753 0.22025  -0.08180 -0.02829 258 VAL A C   
1795 O O   . VAL A 231 ? 0.36455 0.42198 0.28925 0.21930  -0.08047 -0.03220 258 VAL A O   
1796 C CB  . VAL A 231 ? 0.39808 0.43097 0.30579 0.23682  -0.08348 -0.04098 258 VAL A CB  
1797 C CG1 . VAL A 231 ? 0.43199 0.45224 0.34058 0.22412  -0.07648 -0.03803 258 VAL A CG1 
1798 C CG2 . VAL A 231 ? 0.43334 0.45741 0.33007 0.25517  -0.09284 -0.04967 258 VAL A CG2 
1799 N N   . LEU A 232 ? 0.37363 0.37449 0.27568 0.20941  -0.07836 -0.01971 259 LEU A N   
1800 C CA  . LEU A 232 ? 0.35205 0.36201 0.25957 0.19919  -0.07305 -0.01636 259 LEU A CA  
1801 C C   . LEU A 232 ? 0.34106 0.33620 0.25502 0.18421  -0.06414 -0.01011 259 LEU A C   
1802 O O   . LEU A 232 ? 0.34455 0.30878 0.24964 0.18069  -0.06485 -0.00236 259 LEU A O   
1803 C CB  . LEU A 232 ? 0.37546 0.37247 0.26360 0.20434  -0.07822 -0.00918 259 LEU A CB  
1804 C CG  . LEU A 232 ? 0.36135 0.36578 0.24829 0.19784  -0.07372 -0.00748 259 LEU A CG  
1805 C CD1 . LEU A 232 ? 0.35286 0.39497 0.26153 0.19766  -0.07582 -0.02165 259 LEU A CD1 
1806 C CD2 . LEU A 232 ? 0.39670 0.39088 0.25766 0.20681  -0.07816 0.00200  259 LEU A CD2 
1807 N N   A VAL A 233 ? 0.29817 0.31665 0.23393 0.17420  -0.05675 -0.01222 260 VAL A N   
1808 N N   B VAL A 233 ? 0.29827 0.31623 0.23379 0.17410  -0.05672 -0.01208 260 VAL A N   
1809 C CA  A VAL A 233 ? 0.27464 0.28370 0.22138 0.15926  -0.04773 -0.00570 260 VAL A CA  
1810 C CA  B VAL A 233 ? 0.27613 0.28279 0.22133 0.15933  -0.04791 -0.00527 260 VAL A CA  
1811 C C   A VAL A 233 ? 0.28144 0.29732 0.23642 0.15244  -0.04461 -0.00371 260 VAL A C   
1812 C C   B VAL A 233 ? 0.28068 0.29637 0.23618 0.15204  -0.04432 -0.00355 260 VAL A C   
1813 O O   A VAL A 233 ? 0.26360 0.30882 0.23461 0.15492  -0.04791 -0.01186 260 VAL A O   
1814 O O   B VAL A 233 ? 0.26189 0.30768 0.23483 0.15401  -0.04726 -0.01160 260 VAL A O   
1815 C CB  A VAL A 233 ? 0.26158 0.29540 0.23202 0.15407  -0.04128 -0.00801 260 VAL A CB  
1816 C CB  B VAL A 233 ? 0.25959 0.28614 0.22495 0.15470  -0.04183 -0.00752 260 VAL A CB  
1817 C CG1 A VAL A 233 ? 0.22714 0.26148 0.21781 0.13783  -0.03194 -0.00117 260 VAL A CG1 
1818 C CG1 B VAL A 233 ? 0.28106 0.30376 0.23085 0.16877  -0.04776 -0.01396 260 VAL A CG1 
1819 C CG2 A VAL A 233 ? 0.32548 0.34778 0.28053 0.16329  -0.04445 -0.01171 260 VAL A CG2 
1820 C CG2 B VAL A 233 ? 0.25161 0.31900 0.24952 0.14998  -0.03804 -0.00961 260 VAL A CG2 
1821 N N   . THR A 234 ? 0.25982 0.24921 0.20600 0.14419  -0.03940 0.00621  261 THR A N   
1822 C CA  . THR A 234 ? 0.24986 0.24394 0.20053 0.14060  -0.03528 0.00745  261 THR A CA  
1823 C C   . THR A 234 ? 0.32388 0.30258 0.29023 0.12343  -0.02395 0.01684  261 THR A C   
1824 O O   . THR A 234 ? 0.29263 0.24086 0.24711 0.11538  -0.02151 0.02791  261 THR A O   
1825 C CB  . THR A 234 ? 0.31758 0.29582 0.23419 0.15131  -0.03865 0.01369  261 THR A CB  
1826 O OG1 . THR A 234 ? 0.33305 0.27668 0.23501 0.14466  -0.03578 0.02997  261 THR A OG1 
1827 C CG2 . THR A 234 ? 0.36077 0.35799 0.26227 0.16912  -0.05087 0.00349  261 THR A CG2 
1828 N N   A TYR A 235 ? 0.20791 0.21087 0.20964 0.11469  -0.01788 0.01208  262 TYR A N   
1829 N N   B TYR A 235 ? 0.20822 0.21107 0.20972 0.11477  -0.01790 0.01208  262 TYR A N   
1830 C CA  A TYR A 235 ? 0.20760 0.19918 0.22871 0.09781  -0.00628 0.02087  262 TYR A CA  
1831 C CA  B TYR A 235 ? 0.20765 0.19882 0.22819 0.09794  -0.00631 0.02094  262 TYR A CA  
1832 C C   A TYR A 235 ? 0.22485 0.22415 0.26184 0.09150  0.00124  0.01759  262 TYR A C   
1833 C C   B TYR A 235 ? 0.22491 0.22392 0.26130 0.09168  0.00118  0.01759  262 TYR A C   
1834 O O   A TYR A 235 ? 0.22153 0.25206 0.27798 0.09399  -0.00464 0.00142  262 TYR A O   
1835 O O   B TYR A 235 ? 0.22189 0.25185 0.27691 0.09447  -0.00482 0.00140  262 TYR A O   
1836 C CB  A TYR A 235 ? 0.18556 0.20333 0.24303 0.08730  -0.00295 0.01916  262 TYR A CB  
1837 C CB  B TYR A 235 ? 0.18633 0.20316 0.24273 0.08755  -0.00303 0.01925  262 TYR A CB  
1838 C CG  A TYR A 235 ? 0.19017 0.19869 0.23140 0.09072  -0.00687 0.02098  262 TYR A CG  
1839 C CG  B TYR A 235 ? 0.19091 0.19921 0.23114 0.09135  -0.00720 0.02077  262 TYR A CG  
1840 C CD1 A TYR A 235 ? 0.21488 0.19589 0.24562 0.08185  -0.00564 0.02733  262 TYR A CD1 
1841 C CD1 B TYR A 235 ? 0.22723 0.20045 0.23575 0.09461  -0.01246 0.02439  262 TYR A CD1 
1842 C CD2 A TYR A 235 ? 0.22663 0.25486 0.26367 0.10252  -0.01246 0.01452  262 TYR A CD2 
1843 C CD2 B TYR A 235 ? 0.15079 0.18883 0.21163 0.09024  -0.00566 0.01824  262 TYR A CD2 
1844 C CE1 A TYR A 235 ? 0.20674 0.18166 0.22606 0.08782  -0.01083 0.02528  262 TYR A CE1 
1845 C CE1 B TYR A 235 ? 0.21891 0.18687 0.21836 0.09960  -0.01704 0.02178  262 TYR A CE1 
1846 C CE2 A TYR A 235 ? 0.25581 0.27721 0.27644 0.10929  -0.01516 0.01331  262 TYR A CE2 
1847 C CE2 B TYR A 235 ? 0.17917 0.21258 0.22226 0.09824  -0.00832 0.01756  262 TYR A CE2 
1848 C CZ  A TYR A 235 ? 0.27991 0.27500 0.29217 0.10307  -0.01462 0.01774  262 TYR A CZ  
1849 C CZ  B TYR A 235 ? 0.27934 0.27673 0.29132 0.10434  -0.01493 0.01707  262 TYR A CZ  
1850 O OH  A TYR A 235 ? 0.28440 0.27293 0.28128 0.11204  -0.01938 0.01300  262 TYR A OH  
1851 O OH  B TYR A 235 ? 0.29975 0.29295 0.29592 0.11451  -0.01978 0.01175  262 TYR A OH  
1852 N N   . PHE A 236 ? 0.17077 0.14377 0.20467 0.07648  0.01292  0.02961  263 PHE A N   
1853 C CA  . PHE A 236 ? 0.17295 0.15352 0.21990 0.06546  0.02073  0.02311  263 PHE A CA  
1854 C C   . PHE A 236 ? 0.23470 0.19867 0.30424 0.04309  0.03524  0.03632  263 PHE A C   
1855 O O   . PHE A 236 ? 0.19786 0.13926 0.24436 0.03484  0.03576  0.04839  263 PHE A O   
1856 C CB  . PHE A 236 ? 0.20441 0.17224 0.20548 0.08029  0.01926  0.02523  263 PHE A CB  
1857 C CG  . PHE A 236 ? 0.20349 0.18346 0.21065 0.07510  0.02705  0.01475  263 PHE A CG  
1858 C CD1 . PHE A 236 ? 0.18910 0.20326 0.22114 0.07808  0.01825  -0.01343 263 PHE A CD1 
1859 C CD2 . PHE A 236 ? 0.22407 0.18208 0.21647 0.06804  0.04234  0.03246  263 PHE A CD2 
1860 C CE1 . PHE A 236 ? 0.20077 0.22541 0.23784 0.07666  0.02342  -0.02830 263 PHE A CE1 
1861 C CE2 . PHE A 236 ? 0.25545 0.22764 0.25187 0.06666  0.05079  0.02126  263 PHE A CE2 
1862 C CZ  . PHE A 236 ? 0.25081 0.25632 0.26798 0.07222  0.04049  -0.01203 263 PHE A CZ  
1863 N N   . THR A 237 ? 0.14057 0.12578 0.25321 0.02799  0.04090  0.02674  264 THR A N   
1864 C CA  . THR A 237 ? 0.12541 0.10739 0.25457 0.00841  0.05037  0.03392  264 THR A CA  
1865 C C   . THR A 237 ? 0.19344 0.18032 0.34685 0.00304  0.05361  0.02063  264 THR A C   
1866 O O   . THR A 237 ? 0.17990 0.19290 0.35996 0.00646  0.04906  0.00136  264 THR A O   
1867 C CB  . THR A 237 ? 0.15593 0.15202 0.28829 0.00861  0.03922  0.03121  264 THR A CB  
1868 O OG1 . THR A 237 ? 0.16100 0.15710 0.28839 0.00902  0.03926  0.03145  264 THR A OG1 
1869 C CG2 . THR A 237 ? 0.20107 0.19917 0.35128 0.00472  0.03182  0.02498  264 THR A CG2 
1870 N N   . GLN A 238 ? 0.21745 0.16008 0.19874 0.04744  -0.00489 -0.00729 265 GLN A N   
1871 C CA  . GLN A 238 ? 0.22891 0.15548 0.22152 0.05137  -0.00652 -0.01589 265 GLN A CA  
1872 C C   . GLN A 238 ? 0.25290 0.16756 0.25055 0.06538  -0.01697 -0.00972 265 GLN A C   
1873 O O   . GLN A 238 ? 0.26808 0.19426 0.26038 0.07302  -0.02227 -0.00036 265 GLN A O   
1874 C CB  . GLN A 238 ? 0.24176 0.18861 0.24533 0.05459  0.00171  -0.03105 265 GLN A CB  
1875 C CG  . GLN A 238 ? 0.26691 0.21939 0.26123 0.04231  0.01073  -0.03179 265 GLN A CG  
1876 C CD  . GLN A 238 ? 0.25190 0.22655 0.25791 0.04403  0.02310  -0.03586 265 GLN A CD  
1877 O OE1 . GLN A 238 ? 0.29954 0.27864 0.30194 0.05729  0.03067  -0.04292 265 GLN A OE1 
1878 N NE2 . GLN A 238 ? 0.23245 0.22139 0.25302 0.03305  0.02420  -0.02990 265 GLN A NE2 
1879 N N   . PRO A 239 ? 0.29400 0.18182 0.29681 0.07420  -0.02364 -0.01688 266 PRO A N   
1880 C CA  . PRO A 239 ? 0.31218 0.17875 0.31819 0.08994  -0.03703 -0.00780 266 PRO A CA  
1881 C C   . PRO A 239 ? 0.33490 0.22943 0.35308 0.11174  -0.03965 -0.01888 266 PRO A C   
1882 O O   . PRO A 239 ? 0.39887 0.28221 0.41594 0.12695  -0.05235 -0.00830 266 PRO A O   
1883 C CB  . PRO A 239 ? 0.38550 0.20251 0.39278 0.09494  -0.05000 -0.01715 266 PRO A CB  
1884 C CG  . PRO A 239 ? 0.38506 0.20076 0.38692 0.08171  -0.04518 -0.03065 266 PRO A CG  
1885 C CD  . PRO A 239 ? 0.29361 0.15682 0.29201 0.07086  -0.02573 -0.03053 266 PRO A CD  
1886 N N   A GLN A 240 ? 0.31876 0.25324 0.35322 0.11287  -0.02875 -0.03477 267 GLN A N   
1887 N N   B GLN A 240 ? 0.32002 0.25310 0.35468 0.11426  -0.02890 -0.03559 267 GLN A N   
1888 C CA  A GLN A 240 ? 0.34057 0.31439 0.40415 0.13118  -0.03092 -0.04324 267 GLN A CA  
1889 C CA  B GLN A 240 ? 0.34052 0.31250 0.40368 0.13271  -0.03188 -0.04316 267 GLN A CA  
1890 C C   A GLN A 240 ? 0.30356 0.31176 0.38365 0.12038  -0.03787 -0.03942 267 GLN A C   
1891 C C   B GLN A 240 ? 0.30363 0.31141 0.38349 0.11979  -0.03663 -0.03969 267 GLN A C   
1892 O O   A GLN A 240 ? 0.26595 0.28122 0.34396 0.09986  -0.03176 -0.03874 267 GLN A O   
1893 O O   B GLN A 240 ? 0.26441 0.27802 0.34133 0.09911  -0.02915 -0.03894 267 GLN A O   
1894 C CB  A GLN A 240 ? 0.34649 0.35252 0.42740 0.13970  -0.01287 -0.05655 267 GLN A CB  
1895 C CB  B GLN A 240 ? 0.34623 0.34989 0.42805 0.14574  -0.01572 -0.05761 267 GLN A CB  
1896 C CG  A GLN A 240 ? 0.44303 0.41112 0.49747 0.15906  -0.01202 -0.07058 267 GLN A CG  
1897 C CG  B GLN A 240 ? 0.44200 0.40523 0.49878 0.16785  -0.01744 -0.07177 267 GLN A CG  
1898 C CD  A GLN A 240 ? 0.42871 0.37513 0.45582 0.14256  -0.00401 -0.07426 267 GLN A CD  
1899 C CD  B GLN A 240 ? 0.44850 0.38182 0.50214 0.18508  -0.03552 -0.07038 267 GLN A CD  
1900 O OE1 A GLN A 240 ? 0.31727 0.26940 0.34203 0.11522  0.00153  -0.06283 267 GLN A OE1 
1901 O OE1 B GLN A 240 ? 0.55694 0.51958 0.63317 0.19658  -0.04122 -0.06555 267 GLN A OE1 
1902 N NE2 A GLN A 240 ? 0.54564 0.46807 0.54942 0.15869  -0.00660 -0.09053 267 GLN A NE2 
1903 N NE2 B GLN A 240 ? 0.56364 0.43862 0.59248 0.18528  -0.04781 -0.07413 267 GLN A NE2 
1904 N N   A GLN A 241 ? 0.29562 0.32078 0.39096 0.13715  -0.05591 -0.03970 268 GLN A N   
1905 N N   B GLN A 241 ? 0.29733 0.32431 0.39381 0.13481  -0.05450 -0.04012 268 GLN A N   
1906 C CA  A GLN A 241 ? 0.28803 0.33683 0.39388 0.13074  -0.07365 -0.04229 268 GLN A CA  
1907 C CA  B GLN A 241 ? 0.29148 0.34007 0.39709 0.12633  -0.07102 -0.04253 268 GLN A CA  
1908 C C   A GLN A 241 ? 0.30861 0.39805 0.46307 0.11040  -0.06909 -0.04942 268 GLN A C   
1909 C C   B GLN A 241 ? 0.30409 0.38994 0.45521 0.10504  -0.06493 -0.04875 268 GLN A C   
1910 O O   A GLN A 241 ? 0.24112 0.33161 0.39946 0.09632  -0.08460 -0.05430 268 GLN A O   
1911 O O   B GLN A 241 ? 0.22736 0.30616 0.37346 0.08798  -0.07310 -0.05153 268 GLN A O   
1912 C CB  A GLN A 241 ? 0.29111 0.35344 0.40520 0.15638  -0.09930 -0.04367 268 GLN A CB  
1913 C CB  B GLN A 241 ? 0.28404 0.34929 0.40096 0.14988  -0.09731 -0.04508 268 GLN A CB  
1914 C CG  A GLN A 241 ? 0.30072 0.38150 0.41779 0.15642  -0.12890 -0.05317 268 GLN A CG  
1915 C CG  B GLN A 241 ? 0.30624 0.38477 0.42283 0.14654  -0.12421 -0.05435 268 GLN A CG  
1916 C CD  A GLN A 241 ? 0.39959 0.48499 0.50470 0.18114  -0.15285 -0.05252 268 GLN A CD  
1917 C CD  B GLN A 241 ? 0.35709 0.47830 0.52350 0.15815  -0.15232 -0.06558 268 GLN A CD  
1918 O OE1 A GLN A 241 ? 0.35340 0.45913 0.49006 0.19141  -0.15293 -0.05213 268 GLN A OE1 
1919 O OE1 B GLN A 241 ? 0.39953 0.54423 0.59702 0.16816  -0.14488 -0.06221 268 GLN A OE1 
1920 N NE2 A GLN A 241 ? 0.43708 0.50352 0.48893 0.18999  -0.16775 -0.05143 268 GLN A NE2 
1921 N NE2 B GLN A 241 ? 0.39998 0.52445 0.56571 0.15146  -0.18011 -0.07874 268 GLN A NE2 
1922 N N   A ASN A 242 ? 0.25177 0.37313 0.44181 0.11083  -0.04849 -0.04827 269 ASN A N   
1923 N N   B ASN A 242 ? 0.25224 0.37866 0.44872 0.10815  -0.05050 -0.04837 269 ASN A N   
1924 C CA  A ASN A 242 ? 0.28192 0.45251 0.52943 0.09095  -0.03901 -0.04317 269 ASN A CA  
1925 C CA  B ASN A 242 ? 0.27949 0.45023 0.53034 0.08584  -0.04103 -0.04271 269 ASN A CA  
1926 C C   A ASN A 242 ? 0.27528 0.43827 0.50625 0.07659  -0.00942 -0.03472 269 ASN A C   
1927 C C   B ASN A 242 ? 0.27466 0.43772 0.50651 0.07501  -0.00954 -0.03432 269 ASN A C   
1928 O O   A ASN A 242 ? 0.28130 0.49100 0.55684 0.06649  0.00889  -0.02185 269 ASN A O   
1929 O O   B ASN A 242 ? 0.28119 0.49091 0.55590 0.06644  0.01010  -0.02149 269 ASN A O   
1930 C CB  A ASN A 242 ? 0.28998 0.52685 0.59966 0.10761  -0.03414 -0.04063 269 ASN A CB  
1931 C CB  B ASN A 242 ? 0.29071 0.53135 0.61274 0.09681  -0.04017 -0.03924 269 ASN A CB  
1932 C CG  A ASN A 242 ? 0.24141 0.47182 0.52275 0.14314  -0.01761 -0.04638 269 ASN A CG  
1933 C CG  B ASN A 242 ? 0.33035 0.58575 0.67988 0.10644  -0.07832 -0.04875 269 ASN A CG  
1934 O OD1 A ASN A 242 ? 0.28409 0.45914 0.50643 0.14887  -0.00992 -0.05114 269 ASN A OD1 
1935 O OD1 B ASN A 242 ? 0.39575 0.62737 0.73647 0.09355  -0.10816 -0.05674 269 ASN A OD1 
1936 N ND2 A ASN A 242 ? 0.38433 0.67076 0.71151 0.16861  -0.01609 -0.04745 269 ASN A ND2 
1937 N ND2 B ASN A 242 ? 0.38058 0.67466 0.75846 0.13505  -0.08041 -0.05078 269 ASN A ND2 
1938 N N   . ALA A 243 ? 0.24320 0.35402 0.41442 0.07621  -0.00452 -0.03794 270 ALA A N   
1939 C CA  . ALA A 243 ? 0.20096 0.30205 0.34959 0.06736  0.01822  -0.03277 270 ALA A CA  
1940 C C   . ALA A 243 ? 0.26071 0.37139 0.43278 0.04004  0.01912  -0.02132 270 ALA A C   
1941 O O   . ALA A 243 ? 0.23375 0.33215 0.41748 0.02735  -0.00439 -0.02474 270 ALA A O   
1942 C CB  . ALA A 243 ? 0.27564 0.32280 0.36782 0.06922  0.01541  -0.03844 270 ALA A CB  
1943 N N   . GLU A 244 ? 0.26216 0.39102 0.43702 0.03484  0.04385  -0.00789 271 GLU A N   
1944 C CA  . GLU A 244 ? 0.28131 0.41040 0.47688 0.00862  0.04585  0.00948  271 GLU A CA  
1945 C C   . GLU A 244 ? 0.23478 0.30875 0.37927 0.00222  0.03624  0.00217  271 GLU A C   
1946 O O   . GLU A 244 ? 0.25711 0.30585 0.35269 0.01557  0.03954  -0.00882 271 GLU A O   
1947 C CB  . GLU A 244 ? 0.32648 0.49731 0.53509 0.00976  0.07972  0.03415  271 GLU A CB  
1948 C CG  . GLU A 244 ? 0.47367 0.71679 0.73772 0.02144  0.09638  0.04593  271 GLU A CG  
1949 C CD  . GLU A 244 ? 0.86506 1.16379 1.14252 0.02620  0.13577  0.07834  271 GLU A CD  
1950 O OE1 . GLU A 244 ? 0.78291 1.05519 1.01525 0.02337  0.14800  0.08874  271 GLU A OE1 
1951 O OE2 . GLU A 244 ? 0.82402 1.18908 1.14800 0.03451  0.15132  0.09225  271 GLU A OE2 
1952 N N   . SER A 245 ? 0.25164 0.30733 0.41322 -0.01800 0.02181  0.00892  272 SER A N   
1953 C CA  A SER A 245 ? 0.24683 0.25632 0.36116 -0.01763 0.01325  0.00140  272 SER A CA  
1954 C CA  B SER A 245 ? 0.24708 0.25649 0.36253 -0.01828 0.01311  0.00192  272 SER A CA  
1955 C C   . SER A 245 ? 0.28190 0.28931 0.36202 -0.01289 0.03771  0.01280  272 SER A C   
1956 O O   . SER A 245 ? 0.28310 0.32060 0.37711 -0.01364 0.06052  0.03209  272 SER A O   
1957 C CB  A SER A 245 ? 0.33279 0.31396 0.46901 -0.03420 -0.01193 0.00256  272 SER A CB  
1958 C CB  B SER A 245 ? 0.32893 0.31182 0.46961 -0.03623 -0.01075 0.00516  272 SER A CB  
1959 O OG  A SER A 245 ? 0.38817 0.37695 0.55826 -0.05384 0.00008  0.03076  272 SER A OG  
1960 O OG  B SER A 245 ? 0.31831 0.30306 0.49337 -0.03955 -0.04079 -0.00900 272 SER A OG  
1961 N N   . ARG A 246 ? 0.25282 0.23121 0.28786 -0.00469 0.03271  0.00201  273 ARG A N   
1962 C CA  . ARG A 246 ? 0.26793 0.24206 0.26696 0.00294  0.04716  0.00688  273 ARG A CA  
1963 C C   . ARG A 246 ? 0.26324 0.20737 0.24043 0.00094  0.03648  0.00825  273 ARG A C   
1964 O O   . ARG A 246 ? 0.27051 0.20565 0.21960 0.01024  0.03132  -0.00241 273 ARG A O   
1965 C CB  . ARG A 246 ? 0.24594 0.21968 0.21893 0.01730  0.04770  -0.00922 273 ARG A CB  
1966 C CG  . ARG A 246 ? 0.27435 0.27199 0.25795 0.02911  0.05884  -0.01280 273 ARG A CG  
1967 C CD  . ARG A 246 ? 0.32905 0.35105 0.30100 0.04033  0.08070  -0.00169 273 ARG A CD  
1968 N NE  . ARG A 246 ? 0.32182 0.32619 0.24615 0.05132  0.07991  -0.00755 273 ARG A NE  
1969 C CZ  . ARG A 246 ? 0.43109 0.42285 0.32343 0.07046  0.07180  -0.02931 273 ARG A CZ  
1970 N NH1 . ARG A 246 ? 0.41404 0.40182 0.31406 0.08157  0.06485  -0.04619 273 ARG A NH1 
1971 N NH2 . ARG A 246 ? 0.44604 0.42439 0.29845 0.08021  0.06551  -0.03567 273 ARG A NH2 
1972 N N   A ARG A 247 ? 0.28060 0.21006 0.27651 -0.01103 0.03152  0.02349  274 ARG A N   
1973 N N   B ARG A 247 ? 0.28004 0.20953 0.27589 -0.01102 0.03159  0.02354  274 ARG A N   
1974 C CA  A ARG A 247 ? 0.28595 0.18043 0.25846 -0.00694 0.01848  0.02335  274 ARG A CA  
1975 C CA  B ARG A 247 ? 0.28522 0.17969 0.25764 -0.00686 0.01839  0.02316  274 ARG A CA  
1976 C C   A ARG A 247 ? 0.31864 0.21604 0.25219 0.00506  0.03107  0.03019  274 ARG A C   
1977 C C   B ARG A 247 ? 0.31871 0.21598 0.25232 0.00503  0.03101  0.03025  274 ARG A C   
1978 O O   A ARG A 247 ? 0.33188 0.21229 0.24043 0.01648  0.02013  0.02242  274 ARG A O   
1979 O O   B ARG A 247 ? 0.33202 0.21229 0.24059 0.01645  0.02010  0.02250  274 ARG A O   
1980 C CB  A ARG A 247 ? 0.30576 0.17237 0.30978 -0.02354 0.00596  0.04089  274 ARG A CB  
1981 C CB  B ARG A 247 ? 0.30514 0.17168 0.30955 -0.02346 0.00533  0.04001  274 ARG A CB  
1982 C CG  A ARG A 247 ? 0.34121 0.19412 0.37948 -0.03153 -0.02110 0.02419  274 ARG A CG  
1983 C CG  B ARG A 247 ? 0.33557 0.19397 0.37724 -0.03240 -0.01944 0.02422  274 ARG A CG  
1984 C CD  A ARG A 247 ? 0.40955 0.22369 0.48810 -0.05188 -0.04383 0.03932  274 ARG A CD  
1985 C CD  B ARG A 247 ? 0.41460 0.24613 0.50776 -0.05720 -0.03789 0.04337  274 ARG A CD  
1986 N NE  A ARG A 247 ? 0.42839 0.27262 0.55838 -0.07800 -0.02310 0.07897  274 ARG A NE  
1987 N NE  B ARG A 247 ? 0.47356 0.29506 0.60463 -0.06486 -0.07094 0.02292  274 ARG A NE  
1988 C CZ  A ARG A 247 ? 0.47044 0.29528 0.66155 -0.10670 -0.03991 0.10350  274 ARG A CZ  
1989 C CZ  B ARG A 247 ? 0.60426 0.46568 0.78958 -0.08103 -0.06953 0.02934  274 ARG A CZ  
1990 N NH1 A ARG A 247 ? 0.46455 0.23888 0.65888 -0.10631 -0.08076 0.08090  274 ARG A NH1 
1991 N NH1 B ARG A 247 ? 0.44100 0.35813 0.65007 -0.08920 -0.03302 0.05663  274 ARG A NH1 
1992 N NH2 A ARG A 247 ? 0.45173 0.32522 0.68674 -0.12570 -0.01167 0.14440  274 ARG A NH2 
1993 N NH2 B ARG A 247 ? 0.52033 0.36845 0.73439 -0.08385 -0.10776 0.00555  274 ARG A NH2 
1994 N N   . ASP A 248 ? 0.29062 0.21367 0.21640 0.00786  0.05219  0.04261  275 ASP A N   
1995 C CA  . ASP A 248 ? 0.34728 0.27244 0.22829 0.02464  0.05820  0.04407  275 ASP A CA  
1996 C C   . ASP A 248 ? 0.32464 0.24890 0.18703 0.03486  0.04357  0.01716  275 ASP A C   
1997 O O   . ASP A 248 ? 0.35043 0.26958 0.18497 0.04629  0.03555  0.01433  275 ASP A O   
1998 C CB  . ASP A 248 ? 0.39610 0.35282 0.26228 0.03571  0.08183  0.05527  275 ASP A CB  
1999 C CG  . ASP A 248 ? 0.46966 0.44647 0.34610 0.04147  0.08409  0.03341  275 ASP A CG  
2000 O OD1 . ASP A 248 ? 0.34643 0.33105 0.26502 0.02798  0.08340  0.03330  275 ASP A OD1 
2001 O OD2 . ASP A 248 ? 0.52332 0.50241 0.36617 0.06076  0.08072  0.01377  275 ASP A OD2 
2002 N N   . VAL A 249 ? 0.30513 0.23704 0.18723 0.03026  0.03867  0.00118  276 VAL A N   
2003 C CA  . VAL A 249 ? 0.25674 0.19139 0.13555 0.03361  0.02550  -0.01447 276 VAL A CA  
2004 C C   . VAL A 249 ? 0.28062 0.21215 0.16026 0.03632  0.01522  -0.01341 276 VAL A C   
2005 O O   . VAL A 249 ? 0.31447 0.25672 0.18976 0.04188  0.00611  -0.01774 276 VAL A O   
2006 C CB  . VAL A 249 ? 0.29239 0.23291 0.19340 0.02782  0.02416  -0.02270 276 VAL A CB  
2007 C CG1 . VAL A 249 ? 0.32361 0.27029 0.23540 0.02481  0.01191  -0.02665 276 VAL A CG1 
2008 C CG2 . VAL A 249 ? 0.31505 0.25839 0.20983 0.03469  0.03115  -0.02928 276 VAL A CG2 
2009 N N   . LEU A 250 ? 0.26916 0.18805 0.15690 0.03536  0.01320  -0.00995 277 LEU A N   
2010 C CA  . LEU A 250 ? 0.29180 0.20645 0.17280 0.04831  0.00238  -0.01368 277 LEU A CA  
2011 C C   . LEU A 250 ? 0.34280 0.24427 0.20315 0.05842  -0.00228 -0.00691 277 LEU A C   
2012 O O   . LEU A 250 ? 0.30272 0.21837 0.15681 0.07334  -0.00977 -0.01099 277 LEU A O   
2013 C CB  . LEU A 250 ? 0.30651 0.19941 0.19345 0.05085  -0.00691 -0.01911 277 LEU A CB  
2014 C CG  . LEU A 250 ? 0.28271 0.18475 0.18635 0.04366  -0.00631 -0.02503 277 LEU A CG  
2015 C CD1 . LEU A 250 ? 0.28022 0.15991 0.18151 0.05396  -0.02496 -0.03752 277 LEU A CD1 
2016 C CD2 . LEU A 250 ? 0.26974 0.20514 0.17439 0.04736  0.00135  -0.02527 277 LEU A CD2 
2017 N N   . ALA A 251 ? 0.34028 0.22043 0.19218 0.05211  0.00328  0.00777  278 ALA A N   
2018 C CA  . ALA A 251 ? 0.37340 0.23911 0.19885 0.06366  0.00004  0.02036  278 ALA A CA  
2019 C C   . ALA A 251 ? 0.37821 0.27171 0.18573 0.07452  -0.00299 0.01195  278 ALA A C   
2020 O O   . ALA A 251 ? 0.38009 0.27503 0.17256 0.09096  -0.01524 0.01126  278 ALA A O   
2021 C CB  . ALA A 251 ? 0.36430 0.21360 0.18684 0.05310  0.01337  0.04710  278 ALA A CB  
2022 N N   . SER A 252 ? 0.34148 0.25466 0.15253 0.06737  0.00297  0.00318  279 SER A N   
2023 C CA  . SER A 252 ? 0.32912 0.25933 0.12572 0.07645  -0.00919 -0.00937 279 SER A CA  
2024 C C   . SER A 252 ? 0.34697 0.30146 0.17426 0.07454  -0.02466 -0.02003 279 SER A C   
2025 O O   . SER A 252 ? 0.36191 0.33264 0.18749 0.08352  -0.04227 -0.02621 279 SER A O   
2026 C CB  . SER A 252 ? 0.37671 0.31120 0.16928 0.07281  -0.00461 -0.02048 279 SER A CB  
2027 O OG  . SER A 252 ? 0.44639 0.37573 0.20311 0.08459  0.01079  -0.00860 279 SER A OG  
2028 N N   . ALA A 253 ? 0.31464 0.27880 0.17264 0.06411  -0.01844 -0.01983 280 ALA A N   
2029 C CA  . ALA A 253 ? 0.26704 0.26745 0.15805 0.06411  -0.02582 -0.02023 280 ALA A CA  
2030 C C   . ALA A 253 ? 0.30178 0.31352 0.18550 0.08575  -0.03148 -0.01704 280 ALA A C   
2031 O O   . ALA A 253 ? 0.31033 0.36053 0.21634 0.09201  -0.04275 -0.01688 280 ALA A O   
2032 C CB  . ALA A 253 ? 0.29282 0.30416 0.20695 0.05549  -0.01409 -0.01565 280 ALA A CB  
2033 N N   . ALA A 254 ? 0.32310 0.30065 0.18085 0.09795  -0.02736 -0.01437 281 ALA A N   
2034 C CA  . ALA A 254 ? 0.39053 0.36493 0.23467 0.12441  -0.03715 -0.01375 281 ALA A CA  
2035 C C   . ALA A 254 ? 0.42338 0.40209 0.25191 0.13401  -0.05055 -0.01116 281 ALA A C   
2036 O O   . ALA A 254 ? 0.39302 0.40250 0.23092 0.15424  -0.06251 -0.01318 281 ALA A O   
2037 C CB  . ALA A 254 ? 0.40225 0.32036 0.22269 0.13138  -0.03832 -0.01121 281 ALA A CB  
2038 N N   . ARG A 255 ? 0.40534 0.35927 0.20778 0.12465  -0.04891 -0.00664 282 ARG A N   
2039 C CA  A ARG A 255 ? 0.40148 0.35678 0.17505 0.13996  -0.06371 -0.00520 282 ARG A CA  
2040 C CA  B ARG A 255 ? 0.40102 0.35641 0.17469 0.14023  -0.06384 -0.00517 282 ARG A CA  
2041 C C   . ARG A 255 ? 0.38114 0.38551 0.18567 0.13910  -0.08360 -0.02020 282 ARG A C   
2042 O O   . ARG A 255 ? 0.43347 0.45670 0.23728 0.15677  -0.10213 -0.02248 282 ARG A O   
2043 C CB  A ARG A 255 ? 0.41579 0.34557 0.15048 0.13533  -0.05355 0.00257  282 ARG A CB  
2044 C CB  B ARG A 255 ? 0.41597 0.34502 0.14897 0.13671  -0.05419 0.00324  282 ARG A CB  
2045 C CG  A ARG A 255 ? 0.53441 0.46304 0.24121 0.15088  -0.06119 0.00574  282 ARG A CG  
2046 C CG  B ARG A 255 ? 0.53306 0.46495 0.24154 0.15236  -0.06417 0.00387  282 ARG A CG  
2047 C CD  A ARG A 255 ? 0.53713 0.45421 0.21421 0.14874  -0.04281 0.01583  282 ARG A CD  
2048 C CD  B ARG A 255 ? 0.54013 0.45865 0.21467 0.15291  -0.04717 0.01501  282 ARG A CD  
2049 N NE  A ARG A 255 ? 0.58715 0.47862 0.25896 0.13902  -0.01915 0.04343  282 ARG A NE  
2050 N NE  B ARG A 255 ? 0.62455 0.51414 0.28399 0.15006  -0.02628 0.04702  282 ARG A NE  
2051 C CZ  A ARG A 255 ? 0.64421 0.53532 0.32825 0.12279  -0.00140 0.04657  282 ARG A CZ  
2052 C CZ  B ARG A 255 ? 0.68254 0.56213 0.35143 0.13324  -0.00560 0.06070  282 ARG A CZ  
2053 N NH1 A ARG A 255 ? 0.50017 0.41113 0.19793 0.11605  -0.00335 0.02228  282 ARG A NH1 
2054 N NH1 B ARG A 255 ? 0.64410 0.53939 0.32971 0.12150  -0.00045 0.04294  282 ARG A NH1 
2055 N NH2 A ARG A 255 ? 0.62167 0.48984 0.31097 0.11154  0.01639  0.07622  282 ARG A NH2 
2056 N NH2 B ARG A 255 ? 0.73558 0.58823 0.40393 0.12601  0.00825  0.09465  282 ARG A NH2 
2057 N N   . ILE A 256 ? 0.37343 0.39763 0.21499 0.11542  -0.08132 -0.02859 283 ILE A N   
2058 C CA  . ILE A 256 ? 0.34092 0.40828 0.22877 0.10549  -0.10427 -0.03847 283 ILE A CA  
2059 C C   . ILE A 256 ? 0.35936 0.48181 0.29481 0.11376  -0.10665 -0.02952 283 ILE A C   
2060 O O   . ILE A 256 ? 0.37187 0.53643 0.33996 0.11807  -0.13101 -0.03294 283 ILE A O   
2061 C CB  . ILE A 256 ? 0.33980 0.40466 0.25931 0.07697  -0.10073 -0.04295 283 ILE A CB  
2062 C CG1 . ILE A 256 ? 0.37970 0.40362 0.25531 0.07845  -0.10902 -0.05951 283 ILE A CG1 
2063 C CG2 . ILE A 256 ? 0.34033 0.45352 0.33270 0.05769  -0.12110 -0.04136 283 ILE A CG2 
2064 C CD1 . ILE A 256 ? 0.36992 0.37416 0.25894 0.05919  -0.09768 -0.06266 283 ILE A CD1 
2065 N N   . ILE A 257 ? 0.34195 0.47063 0.28393 0.11903  -0.08301 -0.01924 284 ILE A N   
2066 C CA  . ILE A 257 ? 0.31220 0.49866 0.28846 0.13895  -0.07936 -0.01094 284 ILE A CA  
2067 C C   . ILE A 257 ? 0.40771 0.59115 0.35703 0.17369  -0.09461 -0.01481 284 ILE A C   
2068 O O   . ILE A 257 ? 0.45263 0.69183 0.44024 0.18448  -0.10344 -0.01243 284 ILE A O   
2069 C CB  . ILE A 257 ? 0.34121 0.52341 0.30881 0.14770  -0.05377 -0.00574 284 ILE A CB  
2070 C CG1 . ILE A 257 ? 0.34722 0.54275 0.34569 0.11701  -0.04008 0.00304  284 ILE A CG1 
2071 C CG2 . ILE A 257 ? 0.42988 0.66855 0.41365 0.18371  -0.04845 -0.00126 284 ILE A CG2 
2072 C CD1 . ILE A 257 ? 0.46304 0.73798 0.53268 0.10386  -0.03887 0.02171  284 ILE A CD1 
2073 N N   . ALA A 258 ? 0.40444 0.51788 0.29241 0.18606  -0.09405 -0.01712 285 ALA A N   
2074 C CA  . ALA A 258 ? 0.44315 0.53419 0.30564 0.20968  -0.10106 -0.01798 285 ALA A CA  
2075 C C   . ALA A 258 ? 0.52930 0.64368 0.39953 0.20971  -0.12261 -0.02160 285 ALA A C   
2076 O O   . ALA A 258 ? 0.57252 0.69720 0.44161 0.23107  -0.13170 -0.02232 285 ALA A O   
2077 C CB  . ALA A 258 ? 0.51433 0.52468 0.32249 0.21285  -0.09488 -0.01174 285 ALA A CB  
2078 N N   . GLU A 259 ? 0.47852 0.59693 0.35318 0.18829  -0.13408 -0.02726 286 GLU A N   
2079 C CA  . GLU A 259 ? 0.59657 0.73571 0.48114 0.18804  -0.16081 -0.03663 286 GLU A CA  
2080 C C   . GLU A 259 ? 0.68842 0.90342 0.64613 0.18720  -0.17579 -0.03580 286 GLU A C   
2081 O O   . GLU A 259 ? 0.82380 1.05796 0.79114 0.19592  -0.19853 -0.04077 286 GLU A O   
2082 C CB  . GLU A 259 ? 0.57256 0.69524 0.44919 0.16625  -0.17255 -0.04931 286 GLU A CB  
2083 C CG  . GLU A 259 ? 0.76590 0.82678 0.57279 0.17125  -0.15562 -0.04727 286 GLU A CG  
2084 C CD  . GLU A 259 ? 0.99479 1.04130 0.79414 0.15524  -0.16274 -0.06332 286 GLU A CD  
2085 O OE1 . GLU A 259 ? 0.90319 0.97633 0.74937 0.13896  -0.18888 -0.07883 286 GLU A OE1 
2086 O OE2 . GLU A 259 ? 0.96111 0.97083 0.71447 0.15858  -0.14244 -0.05890 286 GLU A OE2 
2087 N N   . GLY A 260 ? 0.69911 0.96330 0.71183 0.17739  -0.16133 -0.02612 287 GLY A N   
2088 C CA  . GLY A 260 ? 0.59349 0.93969 0.68244 0.17792  -0.16449 -0.01566 287 GLY A CA  
2089 C C   . GLY A 260 ? 0.78200 1.14075 0.85685 0.21407  -0.15585 -0.01337 287 GLY A C   
2090 O O   . GLY A 260 ? 0.87333 1.22736 0.93513 0.22959  -0.17620 -0.01938 287 GLY A O   
# 
