data_8R8V
# 
_entry.id   8R8V 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R8V         pdb_00008r8v 10.2210/pdb8r8v/pdb 
WWPDB D_1292133653 ?            ?                   
EMDB  EMD-19012    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R8V 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Human PADI4 in complex with cyclic peptide PADI4_11' 
_pdbx_database_related.db_id          EMD-19012 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              louise.walport@crick.ac.uk 
_pdbx_contact_author.name_first         Louise 
_pdbx_contact_author.name_last          Walport 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-3795-8365 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Benton, D.J.'  1 0000-0001-6748-9339 
'Bertran, M.T.' 2 0000-0002-8336-0903 
'Walport, L.J.' 3 0000-0002-3795-8365 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                9746 
_citation.page_last                 9746 
_citation.title                     
'A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV regulation.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-53554-1 
_citation.pdbx_database_id_PubMed   39528459 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Bertran, M.T.'       1  0000-0002-8336-0903 
primary 'Walmsley, R.'        2  0000-0003-3510-7214 
primary 'Cummings, T.'        3  0000-0001-5214-9796 
primary 'Aramburu, I.V.'      4  ?                   
primary 'Benton, D.J.'        5  0000-0001-6748-9339 
primary 'Mora Molina, R.'     6  0000-0001-7256-732X 
primary 'Assalaarachchi, J.'  7  0000-0002-6067-0845 
primary 'Chasampalioti, M.'   8  0000-0001-9782-3107 
primary 'Swanton, T.'         9  0000-0003-1776-080X 
primary 'Joshi, D.'           10 0000-0001-8660-2528 
primary 'Federico, S.'        11 ?                   
primary 'Okkenhaug, H.'       12 ?                   
primary 'Yu, L.'              13 0000-0001-8378-9112 
primary 'Oxley, D.'           14 ?                   
primary 'Walker, S.'          15 ?                   
primary 'Papayannopoulos, V.' 16 0000-0002-3741-8190 
primary 'Suga, H.'            17 0000-0002-5298-9186 
primary 'Christophorou, M.A.' 18 0000-0001-5455-7283 
primary 'Walport, L.J.'       19 0000-0002-3795-8365 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Protein-arginine deiminase type-4' 74803.719 2  ? ? ? ? 
2 polymer     syn 'Cyclic Peptide PADI4_11'           1557.797  2  ? ? ? ? 
3 non-polymer syn 'CALCIUM ION'                       40.078    10 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;GPLGSPQMAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPDDCTSFSINASPGVVVDIAHSPPAKKKSTGSSTWPLDPG
VEVTLTMKAASGSTGDQKVQISYYGPKTPPVKALLYLTAVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVN
CDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKW
PSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSI
FENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVT
RGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVD
EFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELL
KRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDF
FTYHIRHGEVHCGTNVRRKPFSFKWWNMVP
;
;GPLGSPQMAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPDDCTSFSINASPGVVVDIAHSPPAKKKSTGSSTWPLDPG
VEVTLTMKAASGSTGDQKVQISYYGPKTPPVKALLYLTAVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVN
CDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKW
PSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSI
FENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVT
RGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVD
EFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELL
KRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDF
FTYHIRHGEVHCGTNVRRKPFSFKWWNMVP
;
A,B ? 
2 'polypeptide(L)' no yes 'YESCRYRQVLQL(NH2)' YESCRYRQVLQLX C,D ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        'CALCIUM ION' 
_pdbx_entity_nonpoly.comp_id     CA 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   LEU n 
1 4   GLY n 
1 5   SER n 
1 6   PRO n 
1 7   GLN n 
1 8   MET n 
1 9   ALA n 
1 10  GLN n 
1 11  GLY n 
1 12  THR n 
1 13  LEU n 
1 14  ILE n 
1 15  ARG n 
1 16  VAL n 
1 17  THR n 
1 18  PRO n 
1 19  GLU n 
1 20  GLN n 
1 21  PRO n 
1 22  THR n 
1 23  HIS n 
1 24  ALA n 
1 25  VAL n 
1 26  CYS n 
1 27  VAL n 
1 28  LEU n 
1 29  GLY n 
1 30  THR n 
1 31  LEU n 
1 32  THR n 
1 33  GLN n 
1 34  LEU n 
1 35  ASP n 
1 36  ILE n 
1 37  CYS n 
1 38  SER n 
1 39  SER n 
1 40  ALA n 
1 41  PRO n 
1 42  ASP n 
1 43  ASP n 
1 44  CYS n 
1 45  THR n 
1 46  SER n 
1 47  PHE n 
1 48  SER n 
1 49  ILE n 
1 50  ASN n 
1 51  ALA n 
1 52  SER n 
1 53  PRO n 
1 54  GLY n 
1 55  VAL n 
1 56  VAL n 
1 57  VAL n 
1 58  ASP n 
1 59  ILE n 
1 60  ALA n 
1 61  HIS n 
1 62  SER n 
1 63  PRO n 
1 64  PRO n 
1 65  ALA n 
1 66  LYS n 
1 67  LYS n 
1 68  LYS n 
1 69  SER n 
1 70  THR n 
1 71  GLY n 
1 72  SER n 
1 73  SER n 
1 74  THR n 
1 75  TRP n 
1 76  PRO n 
1 77  LEU n 
1 78  ASP n 
1 79  PRO n 
1 80  GLY n 
1 81  VAL n 
1 82  GLU n 
1 83  VAL n 
1 84  THR n 
1 85  LEU n 
1 86  THR n 
1 87  MET n 
1 88  LYS n 
1 89  ALA n 
1 90  ALA n 
1 91  SER n 
1 92  GLY n 
1 93  SER n 
1 94  THR n 
1 95  GLY n 
1 96  ASP n 
1 97  GLN n 
1 98  LYS n 
1 99  VAL n 
1 100 GLN n 
1 101 ILE n 
1 102 SER n 
1 103 TYR n 
1 104 TYR n 
1 105 GLY n 
1 106 PRO n 
1 107 LYS n 
1 108 THR n 
1 109 PRO n 
1 110 PRO n 
1 111 VAL n 
1 112 LYS n 
1 113 ALA n 
1 114 LEU n 
1 115 LEU n 
1 116 TYR n 
1 117 LEU n 
1 118 THR n 
1 119 ALA n 
1 120 VAL n 
1 121 GLU n 
1 122 ILE n 
1 123 SER n 
1 124 LEU n 
1 125 CYS n 
1 126 ALA n 
1 127 ASP n 
1 128 ILE n 
1 129 THR n 
1 130 ARG n 
1 131 THR n 
1 132 GLY n 
1 133 LYS n 
1 134 VAL n 
1 135 LYS n 
1 136 PRO n 
1 137 THR n 
1 138 ARG n 
1 139 ALA n 
1 140 VAL n 
1 141 LYS n 
1 142 ASP n 
1 143 GLN n 
1 144 ARG n 
1 145 THR n 
1 146 TRP n 
1 147 THR n 
1 148 TRP n 
1 149 GLY n 
1 150 PRO n 
1 151 CYS n 
1 152 GLY n 
1 153 GLN n 
1 154 GLY n 
1 155 ALA n 
1 156 ILE n 
1 157 LEU n 
1 158 LEU n 
1 159 VAL n 
1 160 ASN n 
1 161 CYS n 
1 162 ASP n 
1 163 ARG n 
1 164 ASP n 
1 165 ASN n 
1 166 LEU n 
1 167 GLU n 
1 168 SER n 
1 169 SER n 
1 170 ALA n 
1 171 MET n 
1 172 ASP n 
1 173 CYS n 
1 174 GLU n 
1 175 ASP n 
1 176 ASP n 
1 177 GLU n 
1 178 VAL n 
1 179 LEU n 
1 180 ASP n 
1 181 SER n 
1 182 GLU n 
1 183 ASP n 
1 184 LEU n 
1 185 GLN n 
1 186 ASP n 
1 187 MET n 
1 188 SER n 
1 189 LEU n 
1 190 MET n 
1 191 THR n 
1 192 LEU n 
1 193 SER n 
1 194 THR n 
1 195 LYS n 
1 196 THR n 
1 197 PRO n 
1 198 LYS n 
1 199 ASP n 
1 200 PHE n 
1 201 PHE n 
1 202 THR n 
1 203 ASN n 
1 204 HIS n 
1 205 THR n 
1 206 LEU n 
1 207 VAL n 
1 208 LEU n 
1 209 HIS n 
1 210 VAL n 
1 211 ALA n 
1 212 ARG n 
1 213 SER n 
1 214 GLU n 
1 215 MET n 
1 216 ASP n 
1 217 LYS n 
1 218 VAL n 
1 219 ARG n 
1 220 VAL n 
1 221 PHE n 
1 222 GLN n 
1 223 ALA n 
1 224 THR n 
1 225 ARG n 
1 226 GLY n 
1 227 LYS n 
1 228 LEU n 
1 229 SER n 
1 230 SER n 
1 231 LYS n 
1 232 CYS n 
1 233 SER n 
1 234 VAL n 
1 235 VAL n 
1 236 LEU n 
1 237 GLY n 
1 238 PRO n 
1 239 LYS n 
1 240 TRP n 
1 241 PRO n 
1 242 SER n 
1 243 HIS n 
1 244 TYR n 
1 245 LEU n 
1 246 MET n 
1 247 VAL n 
1 248 PRO n 
1 249 GLY n 
1 250 GLY n 
1 251 LYS n 
1 252 HIS n 
1 253 ASN n 
1 254 MET n 
1 255 ASP n 
1 256 PHE n 
1 257 TYR n 
1 258 VAL n 
1 259 GLU n 
1 260 ALA n 
1 261 LEU n 
1 262 ALA n 
1 263 PHE n 
1 264 PRO n 
1 265 ASP n 
1 266 THR n 
1 267 ASP n 
1 268 PHE n 
1 269 PRO n 
1 270 GLY n 
1 271 LEU n 
1 272 ILE n 
1 273 THR n 
1 274 LEU n 
1 275 THR n 
1 276 ILE n 
1 277 SER n 
1 278 LEU n 
1 279 LEU n 
1 280 ASP n 
1 281 THR n 
1 282 SER n 
1 283 ASN n 
1 284 LEU n 
1 285 GLU n 
1 286 LEU n 
1 287 PRO n 
1 288 GLU n 
1 289 ALA n 
1 290 VAL n 
1 291 VAL n 
1 292 PHE n 
1 293 GLN n 
1 294 ASP n 
1 295 SER n 
1 296 VAL n 
1 297 VAL n 
1 298 PHE n 
1 299 ARG n 
1 300 VAL n 
1 301 ALA n 
1 302 PRO n 
1 303 TRP n 
1 304 ILE n 
1 305 MET n 
1 306 THR n 
1 307 PRO n 
1 308 ASN n 
1 309 THR n 
1 310 GLN n 
1 311 PRO n 
1 312 PRO n 
1 313 GLN n 
1 314 GLU n 
1 315 VAL n 
1 316 TYR n 
1 317 ALA n 
1 318 CYS n 
1 319 SER n 
1 320 ILE n 
1 321 PHE n 
1 322 GLU n 
1 323 ASN n 
1 324 GLU n 
1 325 ASP n 
1 326 PHE n 
1 327 LEU n 
1 328 LYS n 
1 329 SER n 
1 330 VAL n 
1 331 THR n 
1 332 THR n 
1 333 LEU n 
1 334 ALA n 
1 335 MET n 
1 336 LYS n 
1 337 ALA n 
1 338 LYS n 
1 339 CYS n 
1 340 LYS n 
1 341 LEU n 
1 342 THR n 
1 343 ILE n 
1 344 CYS n 
1 345 PRO n 
1 346 GLU n 
1 347 GLU n 
1 348 GLU n 
1 349 ASN n 
1 350 MET n 
1 351 ASP n 
1 352 ASP n 
1 353 GLN n 
1 354 TRP n 
1 355 MET n 
1 356 GLN n 
1 357 ASP n 
1 358 GLU n 
1 359 MET n 
1 360 GLU n 
1 361 ILE n 
1 362 GLY n 
1 363 TYR n 
1 364 ILE n 
1 365 GLN n 
1 366 ALA n 
1 367 PRO n 
1 368 HIS n 
1 369 LYS n 
1 370 THR n 
1 371 LEU n 
1 372 PRO n 
1 373 VAL n 
1 374 VAL n 
1 375 PHE n 
1 376 ASP n 
1 377 SER n 
1 378 PRO n 
1 379 ARG n 
1 380 ASN n 
1 381 ARG n 
1 382 GLY n 
1 383 LEU n 
1 384 LYS n 
1 385 GLU n 
1 386 PHE n 
1 387 PRO n 
1 388 ILE n 
1 389 LYS n 
1 390 ARG n 
1 391 VAL n 
1 392 MET n 
1 393 GLY n 
1 394 PRO n 
1 395 ASP n 
1 396 PHE n 
1 397 GLY n 
1 398 TYR n 
1 399 VAL n 
1 400 THR n 
1 401 ARG n 
1 402 GLY n 
1 403 PRO n 
1 404 GLN n 
1 405 THR n 
1 406 GLY n 
1 407 GLY n 
1 408 ILE n 
1 409 SER n 
1 410 GLY n 
1 411 LEU n 
1 412 ASP n 
1 413 SER n 
1 414 PHE n 
1 415 GLY n 
1 416 ASN n 
1 417 LEU n 
1 418 GLU n 
1 419 VAL n 
1 420 SER n 
1 421 PRO n 
1 422 PRO n 
1 423 VAL n 
1 424 THR n 
1 425 VAL n 
1 426 ARG n 
1 427 GLY n 
1 428 LYS n 
1 429 GLU n 
1 430 TYR n 
1 431 PRO n 
1 432 LEU n 
1 433 GLY n 
1 434 ARG n 
1 435 ILE n 
1 436 LEU n 
1 437 PHE n 
1 438 GLY n 
1 439 ASP n 
1 440 SER n 
1 441 CYS n 
1 442 TYR n 
1 443 PRO n 
1 444 SER n 
1 445 ASN n 
1 446 ASP n 
1 447 SER n 
1 448 ARG n 
1 449 GLN n 
1 450 MET n 
1 451 HIS n 
1 452 GLN n 
1 453 ALA n 
1 454 LEU n 
1 455 GLN n 
1 456 ASP n 
1 457 PHE n 
1 458 LEU n 
1 459 SER n 
1 460 ALA n 
1 461 GLN n 
1 462 GLN n 
1 463 VAL n 
1 464 GLN n 
1 465 ALA n 
1 466 PRO n 
1 467 VAL n 
1 468 LYS n 
1 469 LEU n 
1 470 TYR n 
1 471 SER n 
1 472 ASP n 
1 473 TRP n 
1 474 LEU n 
1 475 SER n 
1 476 VAL n 
1 477 GLY n 
1 478 HIS n 
1 479 VAL n 
1 480 ASP n 
1 481 GLU n 
1 482 PHE n 
1 483 LEU n 
1 484 SER n 
1 485 PHE n 
1 486 VAL n 
1 487 PRO n 
1 488 ALA n 
1 489 PRO n 
1 490 ASP n 
1 491 ARG n 
1 492 LYS n 
1 493 GLY n 
1 494 PHE n 
1 495 ARG n 
1 496 LEU n 
1 497 LEU n 
1 498 LEU n 
1 499 ALA n 
1 500 SER n 
1 501 PRO n 
1 502 ARG n 
1 503 SER n 
1 504 CYS n 
1 505 TYR n 
1 506 LYS n 
1 507 LEU n 
1 508 PHE n 
1 509 GLN n 
1 510 GLU n 
1 511 GLN n 
1 512 GLN n 
1 513 ASN n 
1 514 GLU n 
1 515 GLY n 
1 516 HIS n 
1 517 GLY n 
1 518 GLU n 
1 519 ALA n 
1 520 LEU n 
1 521 LEU n 
1 522 PHE n 
1 523 GLU n 
1 524 GLY n 
1 525 ILE n 
1 526 LYS n 
1 527 LYS n 
1 528 LYS n 
1 529 LYS n 
1 530 GLN n 
1 531 GLN n 
1 532 LYS n 
1 533 ILE n 
1 534 LYS n 
1 535 ASN n 
1 536 ILE n 
1 537 LEU n 
1 538 SER n 
1 539 ASN n 
1 540 LYS n 
1 541 THR n 
1 542 LEU n 
1 543 ARG n 
1 544 GLU n 
1 545 HIS n 
1 546 ASN n 
1 547 SER n 
1 548 PHE n 
1 549 VAL n 
1 550 GLU n 
1 551 ARG n 
1 552 CYS n 
1 553 ILE n 
1 554 ASP n 
1 555 TRP n 
1 556 ASN n 
1 557 ARG n 
1 558 GLU n 
1 559 LEU n 
1 560 LEU n 
1 561 LYS n 
1 562 ARG n 
1 563 GLU n 
1 564 LEU n 
1 565 GLY n 
1 566 LEU n 
1 567 ALA n 
1 568 GLU n 
1 569 SER n 
1 570 ASP n 
1 571 ILE n 
1 572 ILE n 
1 573 ASP n 
1 574 ILE n 
1 575 PRO n 
1 576 GLN n 
1 577 LEU n 
1 578 PHE n 
1 579 LYS n 
1 580 LEU n 
1 581 LYS n 
1 582 GLU n 
1 583 PHE n 
1 584 SER n 
1 585 LYS n 
1 586 ALA n 
1 587 GLU n 
1 588 ALA n 
1 589 PHE n 
1 590 PHE n 
1 591 PRO n 
1 592 ASN n 
1 593 MET n 
1 594 VAL n 
1 595 ASN n 
1 596 MET n 
1 597 LEU n 
1 598 VAL n 
1 599 LEU n 
1 600 GLY n 
1 601 LYS n 
1 602 HIS n 
1 603 LEU n 
1 604 GLY n 
1 605 ILE n 
1 606 PRO n 
1 607 LYS n 
1 608 PRO n 
1 609 PHE n 
1 610 GLY n 
1 611 PRO n 
1 612 VAL n 
1 613 ILE n 
1 614 ASN n 
1 615 GLY n 
1 616 ARG n 
1 617 CYS n 
1 618 CYS n 
1 619 LEU n 
1 620 GLU n 
1 621 GLU n 
1 622 LYS n 
1 623 VAL n 
1 624 CYS n 
1 625 SER n 
1 626 LEU n 
1 627 LEU n 
1 628 GLU n 
1 629 PRO n 
1 630 LEU n 
1 631 GLY n 
1 632 LEU n 
1 633 GLN n 
1 634 CYS n 
1 635 THR n 
1 636 PHE n 
1 637 ILE n 
1 638 ASN n 
1 639 ASP n 
1 640 PHE n 
1 641 PHE n 
1 642 THR n 
1 643 TYR n 
1 644 HIS n 
1 645 ILE n 
1 646 ARG n 
1 647 HIS n 
1 648 GLY n 
1 649 GLU n 
1 650 VAL n 
1 651 HIS n 
1 652 CYS n 
1 653 GLY n 
1 654 THR n 
1 655 ASN n 
1 656 VAL n 
1 657 ARG n 
1 658 ARG n 
1 659 LYS n 
1 660 PRO n 
1 661 PHE n 
1 662 SER n 
1 663 PHE n 
1 664 LYS n 
1 665 TRP n 
1 666 TRP n 
1 667 ASN n 
1 668 MET n 
1 669 VAL n 
1 670 PRO n 
2 1   TYR n 
2 2   GLU n 
2 3   SER n 
2 4   CYS n 
2 5   ARG n 
2 6   TYR n 
2 7   ARG n 
2 8   GLN n 
2 9   VAL n 
2 10  LEU n 
2 11  GLN n 
2 12  LEU n 
2 13  NH2 n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   670 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PADI4 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              2 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       13 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CA  non-polymer         . 'CALCIUM ION'   ? 'Ca 2'           40.078  
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
NH2 non-polymer         . 'AMINO GROUP'   ? 'H2 N'           16.023  
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -6  ?   ?   ?   A . n 
A 1 2   PRO 2   -5  ?   ?   ?   A . n 
A 1 3   LEU 3   -4  ?   ?   ?   A . n 
A 1 4   GLY 4   -3  ?   ?   ?   A . n 
A 1 5   SER 5   -2  ?   ?   ?   A . n 
A 1 6   PRO 6   -1  ?   ?   ?   A . n 
A 1 7   GLN 7   0   ?   ?   ?   A . n 
A 1 8   MET 8   1   ?   ?   ?   A . n 
A 1 9   ALA 9   2   ?   ?   ?   A . n 
A 1 10  GLN 10  3   ?   ?   ?   A . n 
A 1 11  GLY 11  4   4   GLY GLY A . n 
A 1 12  THR 12  5   5   THR THR A . n 
A 1 13  LEU 13  6   6   LEU LEU A . n 
A 1 14  ILE 14  7   7   ILE ILE A . n 
A 1 15  ARG 15  8   8   ARG ARG A . n 
A 1 16  VAL 16  9   9   VAL VAL A . n 
A 1 17  THR 17  10  10  THR THR A . n 
A 1 18  PRO 18  11  11  PRO PRO A . n 
A 1 19  GLU 19  12  12  GLU GLU A . n 
A 1 20  GLN 20  13  13  GLN GLN A . n 
A 1 21  PRO 21  14  14  PRO PRO A . n 
A 1 22  THR 22  15  15  THR THR A . n 
A 1 23  HIS 23  16  16  HIS HIS A . n 
A 1 24  ALA 24  17  17  ALA ALA A . n 
A 1 25  VAL 25  18  18  VAL VAL A . n 
A 1 26  CYS 26  19  19  CYS CYS A . n 
A 1 27  VAL 27  20  20  VAL VAL A . n 
A 1 28  LEU 28  21  21  LEU LEU A . n 
A 1 29  GLY 29  22  22  GLY GLY A . n 
A 1 30  THR 30  23  23  THR THR A . n 
A 1 31  LEU 31  24  24  LEU LEU A . n 
A 1 32  THR 32  25  25  THR THR A . n 
A 1 33  GLN 33  26  26  GLN GLN A . n 
A 1 34  LEU 34  27  27  LEU LEU A . n 
A 1 35  ASP 35  28  28  ASP ASP A . n 
A 1 36  ILE 36  29  29  ILE ILE A . n 
A 1 37  CYS 37  30  30  CYS CYS A . n 
A 1 38  SER 38  31  31  SER SER A . n 
A 1 39  SER 39  32  32  SER SER A . n 
A 1 40  ALA 40  33  33  ALA ALA A . n 
A 1 41  PRO 41  34  34  PRO PRO A . n 
A 1 42  ASP 42  35  35  ASP ASP A . n 
A 1 43  ASP 43  36  36  ASP ASP A . n 
A 1 44  CYS 44  37  37  CYS CYS A . n 
A 1 45  THR 45  38  38  THR THR A . n 
A 1 46  SER 46  39  39  SER SER A . n 
A 1 47  PHE 47  40  40  PHE PHE A . n 
A 1 48  SER 48  41  41  SER SER A . n 
A 1 49  ILE 49  42  42  ILE ILE A . n 
A 1 50  ASN 50  43  43  ASN ASN A . n 
A 1 51  ALA 51  44  44  ALA ALA A . n 
A 1 52  SER 52  45  45  SER SER A . n 
A 1 53  PRO 53  46  46  PRO PRO A . n 
A 1 54  GLY 54  47  47  GLY GLY A . n 
A 1 55  VAL 55  48  48  VAL VAL A . n 
A 1 56  VAL 56  49  49  VAL VAL A . n 
A 1 57  VAL 57  50  50  VAL VAL A . n 
A 1 58  ASP 58  51  51  ASP ASP A . n 
A 1 59  ILE 59  52  52  ILE ILE A . n 
A 1 60  ALA 60  53  53  ALA ALA A . n 
A 1 61  HIS 61  54  ?   ?   ?   A . n 
A 1 62  SER 62  55  ?   ?   ?   A . n 
A 1 63  PRO 63  56  ?   ?   ?   A . n 
A 1 64  PRO 64  57  ?   ?   ?   A . n 
A 1 65  ALA 65  58  ?   ?   ?   A . n 
A 1 66  LYS 66  59  ?   ?   ?   A . n 
A 1 67  LYS 67  60  ?   ?   ?   A . n 
A 1 68  LYS 68  61  ?   ?   ?   A . n 
A 1 69  SER 69  62  ?   ?   ?   A . n 
A 1 70  THR 70  63  ?   ?   ?   A . n 
A 1 71  GLY 71  64  ?   ?   ?   A . n 
A 1 72  SER 72  65  ?   ?   ?   A . n 
A 1 73  SER 73  66  66  SER SER A . n 
A 1 74  THR 74  67  67  THR THR A . n 
A 1 75  TRP 75  68  68  TRP TRP A . n 
A 1 76  PRO 76  69  69  PRO PRO A . n 
A 1 77  LEU 77  70  70  LEU LEU A . n 
A 1 78  ASP 78  71  71  ASP ASP A . n 
A 1 79  PRO 79  72  72  PRO PRO A . n 
A 1 80  GLY 80  73  73  GLY GLY A . n 
A 1 81  VAL 81  74  74  VAL VAL A . n 
A 1 82  GLU 82  75  75  GLU GLU A . n 
A 1 83  VAL 83  76  76  VAL VAL A . n 
A 1 84  THR 84  77  77  THR THR A . n 
A 1 85  LEU 85  78  78  LEU LEU A . n 
A 1 86  THR 86  79  79  THR THR A . n 
A 1 87  MET 87  80  80  MET MET A . n 
A 1 88  LYS 88  81  81  LYS LYS A . n 
A 1 89  ALA 89  82  82  ALA ALA A . n 
A 1 90  ALA 90  83  83  ALA ALA A . n 
A 1 91  SER 91  84  84  SER SER A . n 
A 1 92  GLY 92  85  85  GLY GLY A . n 
A 1 93  SER 93  86  86  SER SER A . n 
A 1 94  THR 94  87  87  THR THR A . n 
A 1 95  GLY 95  88  88  GLY GLY A . n 
A 1 96  ASP 96  89  89  ASP ASP A . n 
A 1 97  GLN 97  90  90  GLN GLN A . n 
A 1 98  LYS 98  91  91  LYS LYS A . n 
A 1 99  VAL 99  92  92  VAL VAL A . n 
A 1 100 GLN 100 93  93  GLN GLN A . n 
A 1 101 ILE 101 94  94  ILE ILE A . n 
A 1 102 SER 102 95  95  SER SER A . n 
A 1 103 TYR 103 96  96  TYR TYR A . n 
A 1 104 TYR 104 97  97  TYR TYR A . n 
A 1 105 GLY 105 98  98  GLY GLY A . n 
A 1 106 PRO 106 99  99  PRO PRO A . n 
A 1 107 LYS 107 100 100 LYS LYS A . n 
A 1 108 THR 108 101 101 THR THR A . n 
A 1 109 PRO 109 102 102 PRO PRO A . n 
A 1 110 PRO 110 103 103 PRO PRO A . n 
A 1 111 VAL 111 104 104 VAL VAL A . n 
A 1 112 LYS 112 105 105 LYS LYS A . n 
A 1 113 ALA 113 106 106 ALA ALA A . n 
A 1 114 LEU 114 107 107 LEU LEU A . n 
A 1 115 LEU 115 108 108 LEU LEU A . n 
A 1 116 TYR 116 109 109 TYR TYR A . n 
A 1 117 LEU 117 110 110 LEU LEU A . n 
A 1 118 THR 118 111 111 THR THR A . n 
A 1 119 ALA 119 112 112 ALA ALA A . n 
A 1 120 VAL 120 113 113 VAL VAL A . n 
A 1 121 GLU 121 114 114 GLU GLU A . n 
A 1 122 ILE 122 115 115 ILE ILE A . n 
A 1 123 SER 123 116 116 SER SER A . n 
A 1 124 LEU 124 117 117 LEU LEU A . n 
A 1 125 CYS 125 118 118 CYS CYS A . n 
A 1 126 ALA 126 119 119 ALA ALA A . n 
A 1 127 ASP 127 120 120 ASP ASP A . n 
A 1 128 ILE 128 121 121 ILE ILE A . n 
A 1 129 THR 129 122 122 THR THR A . n 
A 1 130 ARG 130 123 123 ARG ARG A . n 
A 1 131 THR 131 124 124 THR THR A . n 
A 1 132 GLY 132 125 125 GLY GLY A . n 
A 1 133 LYS 133 126 126 LYS LYS A . n 
A 1 134 VAL 134 127 127 VAL VAL A . n 
A 1 135 LYS 135 128 ?   ?   ?   A . n 
A 1 136 PRO 136 129 ?   ?   ?   A . n 
A 1 137 THR 137 130 ?   ?   ?   A . n 
A 1 138 ARG 138 131 ?   ?   ?   A . n 
A 1 139 ALA 139 132 ?   ?   ?   A . n 
A 1 140 VAL 140 133 ?   ?   ?   A . n 
A 1 141 LYS 141 134 ?   ?   ?   A . n 
A 1 142 ASP 142 135 ?   ?   ?   A . n 
A 1 143 GLN 143 136 136 GLN GLN A . n 
A 1 144 ARG 144 137 137 ARG ARG A . n 
A 1 145 THR 145 138 138 THR THR A . n 
A 1 146 TRP 146 139 139 TRP TRP A . n 
A 1 147 THR 147 140 140 THR THR A . n 
A 1 148 TRP 148 141 141 TRP TRP A . n 
A 1 149 GLY 149 142 142 GLY GLY A . n 
A 1 150 PRO 150 143 143 PRO PRO A . n 
A 1 151 CYS 151 144 144 CYS CYS A . n 
A 1 152 GLY 152 145 145 GLY GLY A . n 
A 1 153 GLN 153 146 146 GLN GLN A . n 
A 1 154 GLY 154 147 147 GLY GLY A . n 
A 1 155 ALA 155 148 148 ALA ALA A . n 
A 1 156 ILE 156 149 149 ILE ILE A . n 
A 1 157 LEU 157 150 150 LEU LEU A . n 
A 1 158 LEU 158 151 151 LEU LEU A . n 
A 1 159 VAL 159 152 152 VAL VAL A . n 
A 1 160 ASN 160 153 153 ASN ASN A . n 
A 1 161 CYS 161 154 154 CYS CYS A . n 
A 1 162 ASP 162 155 155 ASP ASP A . n 
A 1 163 ARG 163 156 156 ARG ARG A . n 
A 1 164 ASP 164 157 157 ASP ASP A . n 
A 1 165 ASN 165 158 158 ASN ASN A . n 
A 1 166 LEU 166 159 159 LEU LEU A . n 
A 1 167 GLU 167 160 160 GLU GLU A . n 
A 1 168 SER 168 161 161 SER SER A . n 
A 1 169 SER 169 162 162 SER SER A . n 
A 1 170 ALA 170 163 163 ALA ALA A . n 
A 1 171 MET 171 164 164 MET MET A . n 
A 1 172 ASP 172 165 165 ASP ASP A . n 
A 1 173 CYS 173 166 166 CYS CYS A . n 
A 1 174 GLU 174 167 167 GLU GLU A . n 
A 1 175 ASP 175 168 168 ASP ASP A . n 
A 1 176 ASP 176 169 169 ASP ASP A . n 
A 1 177 GLU 177 170 170 GLU GLU A . n 
A 1 178 VAL 178 171 171 VAL VAL A . n 
A 1 179 LEU 179 172 172 LEU LEU A . n 
A 1 180 ASP 180 173 173 ASP ASP A . n 
A 1 181 SER 181 174 174 SER SER A . n 
A 1 182 GLU 182 175 175 GLU GLU A . n 
A 1 183 ASP 183 176 176 ASP ASP A . n 
A 1 184 LEU 184 177 177 LEU LEU A . n 
A 1 185 GLN 185 178 178 GLN GLN A . n 
A 1 186 ASP 186 179 179 ASP ASP A . n 
A 1 187 MET 187 180 180 MET MET A . n 
A 1 188 SER 188 181 181 SER SER A . n 
A 1 189 LEU 189 182 182 LEU LEU A . n 
A 1 190 MET 190 183 183 MET MET A . n 
A 1 191 THR 191 184 184 THR THR A . n 
A 1 192 LEU 192 185 185 LEU LEU A . n 
A 1 193 SER 193 186 186 SER SER A . n 
A 1 194 THR 194 187 187 THR THR A . n 
A 1 195 LYS 195 188 188 LYS LYS A . n 
A 1 196 THR 196 189 189 THR THR A . n 
A 1 197 PRO 197 190 190 PRO PRO A . n 
A 1 198 LYS 198 191 191 LYS LYS A . n 
A 1 199 ASP 199 192 192 ASP ASP A . n 
A 1 200 PHE 200 193 193 PHE PHE A . n 
A 1 201 PHE 201 194 194 PHE PHE A . n 
A 1 202 THR 202 195 195 THR THR A . n 
A 1 203 ASN 203 196 196 ASN ASN A . n 
A 1 204 HIS 204 197 197 HIS HIS A . n 
A 1 205 THR 205 198 198 THR THR A . n 
A 1 206 LEU 206 199 199 LEU LEU A . n 
A 1 207 VAL 207 200 200 VAL VAL A . n 
A 1 208 LEU 208 201 201 LEU LEU A . n 
A 1 209 HIS 209 202 202 HIS HIS A . n 
A 1 210 VAL 210 203 203 VAL VAL A . n 
A 1 211 ALA 211 204 204 ALA ALA A . n 
A 1 212 ARG 212 205 205 ARG ARG A . n 
A 1 213 SER 213 206 206 SER SER A . n 
A 1 214 GLU 214 207 207 GLU GLU A . n 
A 1 215 MET 215 208 208 MET MET A . n 
A 1 216 ASP 216 209 209 ASP ASP A . n 
A 1 217 LYS 217 210 210 LYS LYS A . n 
A 1 218 VAL 218 211 211 VAL VAL A . n 
A 1 219 ARG 219 212 212 ARG ARG A . n 
A 1 220 VAL 220 213 213 VAL VAL A . n 
A 1 221 PHE 221 214 214 PHE PHE A . n 
A 1 222 GLN 222 215 215 GLN GLN A . n 
A 1 223 ALA 223 216 216 ALA ALA A . n 
A 1 224 THR 224 217 217 THR THR A . n 
A 1 225 ARG 225 218 ?   ?   ?   A . n 
A 1 226 GLY 226 219 ?   ?   ?   A . n 
A 1 227 LYS 227 220 ?   ?   ?   A . n 
A 1 228 LEU 228 221 ?   ?   ?   A . n 
A 1 229 SER 229 222 ?   ?   ?   A . n 
A 1 230 SER 230 223 ?   ?   ?   A . n 
A 1 231 LYS 231 224 224 LYS LYS A . n 
A 1 232 CYS 232 225 225 CYS CYS A . n 
A 1 233 SER 233 226 226 SER SER A . n 
A 1 234 VAL 234 227 227 VAL VAL A . n 
A 1 235 VAL 235 228 228 VAL VAL A . n 
A 1 236 LEU 236 229 229 LEU LEU A . n 
A 1 237 GLY 237 230 230 GLY GLY A . n 
A 1 238 PRO 238 231 231 PRO PRO A . n 
A 1 239 LYS 239 232 232 LYS LYS A . n 
A 1 240 TRP 240 233 233 TRP TRP A . n 
A 1 241 PRO 241 234 234 PRO PRO A . n 
A 1 242 SER 242 235 235 SER SER A . n 
A 1 243 HIS 243 236 236 HIS HIS A . n 
A 1 244 TYR 244 237 237 TYR TYR A . n 
A 1 245 LEU 245 238 238 LEU LEU A . n 
A 1 246 MET 246 239 239 MET MET A . n 
A 1 247 VAL 247 240 240 VAL VAL A . n 
A 1 248 PRO 248 241 241 PRO PRO A . n 
A 1 249 GLY 249 242 242 GLY GLY A . n 
A 1 250 GLY 250 243 243 GLY GLY A . n 
A 1 251 LYS 251 244 244 LYS LYS A . n 
A 1 252 HIS 252 245 245 HIS HIS A . n 
A 1 253 ASN 253 246 246 ASN ASN A . n 
A 1 254 MET 254 247 247 MET MET A . n 
A 1 255 ASP 255 248 248 ASP ASP A . n 
A 1 256 PHE 256 249 249 PHE PHE A . n 
A 1 257 TYR 257 250 250 TYR TYR A . n 
A 1 258 VAL 258 251 251 VAL VAL A . n 
A 1 259 GLU 259 252 252 GLU GLU A . n 
A 1 260 ALA 260 253 253 ALA ALA A . n 
A 1 261 LEU 261 254 254 LEU LEU A . n 
A 1 262 ALA 262 255 255 ALA ALA A . n 
A 1 263 PHE 263 256 256 PHE PHE A . n 
A 1 264 PRO 264 257 257 PRO PRO A . n 
A 1 265 ASP 265 258 258 ASP ASP A . n 
A 1 266 THR 266 259 259 THR THR A . n 
A 1 267 ASP 267 260 260 ASP ASP A . n 
A 1 268 PHE 268 261 261 PHE PHE A . n 
A 1 269 PRO 269 262 262 PRO PRO A . n 
A 1 270 GLY 270 263 263 GLY GLY A . n 
A 1 271 LEU 271 264 264 LEU LEU A . n 
A 1 272 ILE 272 265 265 ILE ILE A . n 
A 1 273 THR 273 266 266 THR THR A . n 
A 1 274 LEU 274 267 267 LEU LEU A . n 
A 1 275 THR 275 268 268 THR THR A . n 
A 1 276 ILE 276 269 269 ILE ILE A . n 
A 1 277 SER 277 270 270 SER SER A . n 
A 1 278 LEU 278 271 271 LEU LEU A . n 
A 1 279 LEU 279 272 272 LEU LEU A . n 
A 1 280 ASP 280 273 273 ASP ASP A . n 
A 1 281 THR 281 274 274 THR THR A . n 
A 1 282 SER 282 275 275 SER SER A . n 
A 1 283 ASN 283 276 276 ASN ASN A . n 
A 1 284 LEU 284 277 277 LEU LEU A . n 
A 1 285 GLU 285 278 278 GLU GLU A . n 
A 1 286 LEU 286 279 279 LEU LEU A . n 
A 1 287 PRO 287 280 280 PRO PRO A . n 
A 1 288 GLU 288 281 281 GLU GLU A . n 
A 1 289 ALA 289 282 282 ALA ALA A . n 
A 1 290 VAL 290 283 283 VAL VAL A . n 
A 1 291 VAL 291 284 284 VAL VAL A . n 
A 1 292 PHE 292 285 285 PHE PHE A . n 
A 1 293 GLN 293 286 286 GLN GLN A . n 
A 1 294 ASP 294 287 287 ASP ASP A . n 
A 1 295 SER 295 288 288 SER SER A . n 
A 1 296 VAL 296 289 289 VAL VAL A . n 
A 1 297 VAL 297 290 290 VAL VAL A . n 
A 1 298 PHE 298 291 291 PHE PHE A . n 
A 1 299 ARG 299 292 292 ARG ARG A . n 
A 1 300 VAL 300 293 293 VAL VAL A . n 
A 1 301 ALA 301 294 294 ALA ALA A . n 
A 1 302 PRO 302 295 295 PRO PRO A . n 
A 1 303 TRP 303 296 296 TRP TRP A . n 
A 1 304 ILE 304 297 297 ILE ILE A . n 
A 1 305 MET 305 298 298 MET MET A . n 
A 1 306 THR 306 299 299 THR THR A . n 
A 1 307 PRO 307 300 300 PRO PRO A . n 
A 1 308 ASN 308 301 301 ASN ASN A . n 
A 1 309 THR 309 302 302 THR THR A . n 
A 1 310 GLN 310 303 303 GLN GLN A . n 
A 1 311 PRO 311 304 304 PRO PRO A . n 
A 1 312 PRO 312 305 305 PRO PRO A . n 
A 1 313 GLN 313 306 306 GLN GLN A . n 
A 1 314 GLU 314 307 307 GLU GLU A . n 
A 1 315 VAL 315 308 308 VAL VAL A . n 
A 1 316 TYR 316 309 309 TYR TYR A . n 
A 1 317 ALA 317 310 310 ALA ALA A . n 
A 1 318 CYS 318 311 311 CYS CYS A . n 
A 1 319 SER 319 312 312 SER SER A . n 
A 1 320 ILE 320 313 313 ILE ILE A . n 
A 1 321 PHE 321 314 314 PHE PHE A . n 
A 1 322 GLU 322 315 315 GLU GLU A . n 
A 1 323 ASN 323 316 316 ASN ASN A . n 
A 1 324 GLU 324 317 317 GLU GLU A . n 
A 1 325 ASP 325 318 318 ASP ASP A . n 
A 1 326 PHE 326 319 319 PHE PHE A . n 
A 1 327 LEU 327 320 320 LEU LEU A . n 
A 1 328 LYS 328 321 321 LYS LYS A . n 
A 1 329 SER 329 322 322 SER SER A . n 
A 1 330 VAL 330 323 323 VAL VAL A . n 
A 1 331 THR 331 324 324 THR THR A . n 
A 1 332 THR 332 325 325 THR THR A . n 
A 1 333 LEU 333 326 326 LEU LEU A . n 
A 1 334 ALA 334 327 327 ALA ALA A . n 
A 1 335 MET 335 328 328 MET MET A . n 
A 1 336 LYS 336 329 329 LYS LYS A . n 
A 1 337 ALA 337 330 330 ALA ALA A . n 
A 1 338 LYS 338 331 331 LYS LYS A . n 
A 1 339 CYS 339 332 332 CYS CYS A . n 
A 1 340 LYS 340 333 333 LYS LYS A . n 
A 1 341 LEU 341 334 334 LEU LEU A . n 
A 1 342 THR 342 335 335 THR THR A . n 
A 1 343 ILE 343 336 336 ILE ILE A . n 
A 1 344 CYS 344 337 337 CYS CYS A . n 
A 1 345 PRO 345 338 338 PRO PRO A . n 
A 1 346 GLU 346 339 339 GLU GLU A . n 
A 1 347 GLU 347 340 340 GLU GLU A . n 
A 1 348 GLU 348 341 341 GLU GLU A . n 
A 1 349 ASN 349 342 342 ASN ASN A . n 
A 1 350 MET 350 343 343 MET MET A . n 
A 1 351 ASP 351 344 344 ASP ASP A . n 
A 1 352 ASP 352 345 345 ASP ASP A . n 
A 1 353 GLN 353 346 346 GLN GLN A . n 
A 1 354 TRP 354 347 347 TRP TRP A . n 
A 1 355 MET 355 348 348 MET MET A . n 
A 1 356 GLN 356 349 349 GLN GLN A . n 
A 1 357 ASP 357 350 350 ASP ASP A . n 
A 1 358 GLU 358 351 351 GLU GLU A . n 
A 1 359 MET 359 352 352 MET MET A . n 
A 1 360 GLU 360 353 353 GLU GLU A . n 
A 1 361 ILE 361 354 354 ILE ILE A . n 
A 1 362 GLY 362 355 355 GLY GLY A . n 
A 1 363 TYR 363 356 356 TYR TYR A . n 
A 1 364 ILE 364 357 357 ILE ILE A . n 
A 1 365 GLN 365 358 358 GLN GLN A . n 
A 1 366 ALA 366 359 359 ALA ALA A . n 
A 1 367 PRO 367 360 360 PRO PRO A . n 
A 1 368 HIS 368 361 361 HIS HIS A . n 
A 1 369 LYS 369 362 362 LYS LYS A . n 
A 1 370 THR 370 363 363 THR THR A . n 
A 1 371 LEU 371 364 364 LEU LEU A . n 
A 1 372 PRO 372 365 365 PRO PRO A . n 
A 1 373 VAL 373 366 366 VAL VAL A . n 
A 1 374 VAL 374 367 367 VAL VAL A . n 
A 1 375 PHE 375 368 368 PHE PHE A . n 
A 1 376 ASP 376 369 369 ASP ASP A . n 
A 1 377 SER 377 370 370 SER SER A . n 
A 1 378 PRO 378 371 371 PRO PRO A . n 
A 1 379 ARG 379 372 372 ARG ARG A . n 
A 1 380 ASN 380 373 373 ASN ASN A . n 
A 1 381 ARG 381 374 374 ARG ARG A . n 
A 1 382 GLY 382 375 375 GLY GLY A . n 
A 1 383 LEU 383 376 376 LEU LEU A . n 
A 1 384 LYS 384 377 377 LYS LYS A . n 
A 1 385 GLU 385 378 378 GLU GLU A . n 
A 1 386 PHE 386 379 379 PHE PHE A . n 
A 1 387 PRO 387 380 380 PRO PRO A . n 
A 1 388 ILE 388 381 381 ILE ILE A . n 
A 1 389 LYS 389 382 382 LYS LYS A . n 
A 1 390 ARG 390 383 383 ARG ARG A . n 
A 1 391 VAL 391 384 384 VAL VAL A . n 
A 1 392 MET 392 385 385 MET MET A . n 
A 1 393 GLY 393 386 386 GLY GLY A . n 
A 1 394 PRO 394 387 387 PRO PRO A . n 
A 1 395 ASP 395 388 388 ASP ASP A . n 
A 1 396 PHE 396 389 389 PHE PHE A . n 
A 1 397 GLY 397 390 390 GLY GLY A . n 
A 1 398 TYR 398 391 391 TYR TYR A . n 
A 1 399 VAL 399 392 392 VAL VAL A . n 
A 1 400 THR 400 393 393 THR THR A . n 
A 1 401 ARG 401 394 394 ARG ARG A . n 
A 1 402 GLY 402 395 395 GLY GLY A . n 
A 1 403 PRO 403 396 396 PRO PRO A . n 
A 1 404 GLN 404 397 397 GLN GLN A . n 
A 1 405 THR 405 398 398 THR THR A . n 
A 1 406 GLY 406 399 399 GLY GLY A . n 
A 1 407 GLY 407 400 400 GLY GLY A . n 
A 1 408 ILE 408 401 401 ILE ILE A . n 
A 1 409 SER 409 402 402 SER SER A . n 
A 1 410 GLY 410 403 403 GLY GLY A . n 
A 1 411 LEU 411 404 404 LEU LEU A . n 
A 1 412 ASP 412 405 405 ASP ASP A . n 
A 1 413 SER 413 406 406 SER SER A . n 
A 1 414 PHE 414 407 407 PHE PHE A . n 
A 1 415 GLY 415 408 408 GLY GLY A . n 
A 1 416 ASN 416 409 409 ASN ASN A . n 
A 1 417 LEU 417 410 410 LEU LEU A . n 
A 1 418 GLU 418 411 411 GLU GLU A . n 
A 1 419 VAL 419 412 412 VAL VAL A . n 
A 1 420 SER 420 413 413 SER SER A . n 
A 1 421 PRO 421 414 414 PRO PRO A . n 
A 1 422 PRO 422 415 415 PRO PRO A . n 
A 1 423 VAL 423 416 416 VAL VAL A . n 
A 1 424 THR 424 417 417 THR THR A . n 
A 1 425 VAL 425 418 418 VAL VAL A . n 
A 1 426 ARG 426 419 419 ARG ARG A . n 
A 1 427 GLY 427 420 420 GLY GLY A . n 
A 1 428 LYS 428 421 421 LYS LYS A . n 
A 1 429 GLU 429 422 422 GLU GLU A . n 
A 1 430 TYR 430 423 423 TYR TYR A . n 
A 1 431 PRO 431 424 424 PRO PRO A . n 
A 1 432 LEU 432 425 425 LEU LEU A . n 
A 1 433 GLY 433 426 426 GLY GLY A . n 
A 1 434 ARG 434 427 427 ARG ARG A . n 
A 1 435 ILE 435 428 428 ILE ILE A . n 
A 1 436 LEU 436 429 429 LEU LEU A . n 
A 1 437 PHE 437 430 430 PHE PHE A . n 
A 1 438 GLY 438 431 431 GLY GLY A . n 
A 1 439 ASP 439 432 432 ASP ASP A . n 
A 1 440 SER 440 433 433 SER SER A . n 
A 1 441 CYS 441 434 434 CYS CYS A . n 
A 1 442 TYR 442 435 435 TYR TYR A . n 
A 1 443 PRO 443 436 436 PRO PRO A . n 
A 1 444 SER 444 437 437 SER SER A . n 
A 1 445 ASN 445 438 438 ASN ASN A . n 
A 1 446 ASP 446 439 439 ASP ASP A . n 
A 1 447 SER 447 440 440 SER SER A . n 
A 1 448 ARG 448 441 441 ARG ARG A . n 
A 1 449 GLN 449 442 442 GLN GLN A . n 
A 1 450 MET 450 443 443 MET MET A . n 
A 1 451 HIS 451 444 444 HIS HIS A . n 
A 1 452 GLN 452 445 445 GLN GLN A . n 
A 1 453 ALA 453 446 446 ALA ALA A . n 
A 1 454 LEU 454 447 447 LEU LEU A . n 
A 1 455 GLN 455 448 448 GLN GLN A . n 
A 1 456 ASP 456 449 449 ASP ASP A . n 
A 1 457 PHE 457 450 450 PHE PHE A . n 
A 1 458 LEU 458 451 451 LEU LEU A . n 
A 1 459 SER 459 452 452 SER SER A . n 
A 1 460 ALA 460 453 453 ALA ALA A . n 
A 1 461 GLN 461 454 454 GLN GLN A . n 
A 1 462 GLN 462 455 455 GLN GLN A . n 
A 1 463 VAL 463 456 456 VAL VAL A . n 
A 1 464 GLN 464 457 457 GLN GLN A . n 
A 1 465 ALA 465 458 458 ALA ALA A . n 
A 1 466 PRO 466 459 459 PRO PRO A . n 
A 1 467 VAL 467 460 460 VAL VAL A . n 
A 1 468 LYS 468 461 461 LYS LYS A . n 
A 1 469 LEU 469 462 462 LEU LEU A . n 
A 1 470 TYR 470 463 463 TYR TYR A . n 
A 1 471 SER 471 464 464 SER SER A . n 
A 1 472 ASP 472 465 465 ASP ASP A . n 
A 1 473 TRP 473 466 466 TRP TRP A . n 
A 1 474 LEU 474 467 467 LEU LEU A . n 
A 1 475 SER 475 468 468 SER SER A . n 
A 1 476 VAL 476 469 469 VAL VAL A . n 
A 1 477 GLY 477 470 470 GLY GLY A . n 
A 1 478 HIS 478 471 471 HIS HIS A . n 
A 1 479 VAL 479 472 472 VAL VAL A . n 
A 1 480 ASP 480 473 473 ASP ASP A . n 
A 1 481 GLU 481 474 474 GLU GLU A . n 
A 1 482 PHE 482 475 475 PHE PHE A . n 
A 1 483 LEU 483 476 476 LEU LEU A . n 
A 1 484 SER 484 477 477 SER SER A . n 
A 1 485 PHE 485 478 478 PHE PHE A . n 
A 1 486 VAL 486 479 479 VAL VAL A . n 
A 1 487 PRO 487 480 480 PRO PRO A . n 
A 1 488 ALA 488 481 481 ALA ALA A . n 
A 1 489 PRO 489 482 482 PRO PRO A . n 
A 1 490 ASP 490 483 483 ASP ASP A . n 
A 1 491 ARG 491 484 484 ARG ARG A . n 
A 1 492 LYS 492 485 485 LYS LYS A . n 
A 1 493 GLY 493 486 486 GLY GLY A . n 
A 1 494 PHE 494 487 487 PHE PHE A . n 
A 1 495 ARG 495 488 488 ARG ARG A . n 
A 1 496 LEU 496 489 489 LEU LEU A . n 
A 1 497 LEU 497 490 490 LEU LEU A . n 
A 1 498 LEU 498 491 491 LEU LEU A . n 
A 1 499 ALA 499 492 492 ALA ALA A . n 
A 1 500 SER 500 493 493 SER SER A . n 
A 1 501 PRO 501 494 494 PRO PRO A . n 
A 1 502 ARG 502 495 495 ARG ARG A . n 
A 1 503 SER 503 496 496 SER SER A . n 
A 1 504 CYS 504 497 497 CYS CYS A . n 
A 1 505 TYR 505 498 498 TYR TYR A . n 
A 1 506 LYS 506 499 499 LYS LYS A . n 
A 1 507 LEU 507 500 500 LEU LEU A . n 
A 1 508 PHE 508 501 501 PHE PHE A . n 
A 1 509 GLN 509 502 502 GLN GLN A . n 
A 1 510 GLU 510 503 503 GLU GLU A . n 
A 1 511 GLN 511 504 504 GLN GLN A . n 
A 1 512 GLN 512 505 505 GLN GLN A . n 
A 1 513 ASN 513 506 506 ASN ASN A . n 
A 1 514 GLU 514 507 507 GLU GLU A . n 
A 1 515 GLY 515 508 508 GLY GLY A . n 
A 1 516 HIS 516 509 509 HIS HIS A . n 
A 1 517 GLY 517 510 510 GLY GLY A . n 
A 1 518 GLU 518 511 511 GLU GLU A . n 
A 1 519 ALA 519 512 512 ALA ALA A . n 
A 1 520 LEU 520 513 513 LEU LEU A . n 
A 1 521 LEU 521 514 514 LEU LEU A . n 
A 1 522 PHE 522 515 515 PHE PHE A . n 
A 1 523 GLU 523 516 516 GLU GLU A . n 
A 1 524 GLY 524 517 517 GLY GLY A . n 
A 1 525 ILE 525 518 518 ILE ILE A . n 
A 1 526 LYS 526 519 519 LYS LYS A . n 
A 1 527 LYS 527 520 520 LYS LYS A . n 
A 1 528 LYS 528 521 521 LYS LYS A . n 
A 1 529 LYS 529 522 522 LYS LYS A . n 
A 1 530 GLN 530 523 523 GLN GLN A . n 
A 1 531 GLN 531 524 524 GLN GLN A . n 
A 1 532 LYS 532 525 525 LYS LYS A . n 
A 1 533 ILE 533 526 526 ILE ILE A . n 
A 1 534 LYS 534 527 527 LYS LYS A . n 
A 1 535 ASN 535 528 528 ASN ASN A . n 
A 1 536 ILE 536 529 529 ILE ILE A . n 
A 1 537 LEU 537 530 530 LEU LEU A . n 
A 1 538 SER 538 531 531 SER SER A . n 
A 1 539 ASN 539 532 532 ASN ASN A . n 
A 1 540 LYS 540 533 533 LYS LYS A . n 
A 1 541 THR 541 534 534 THR THR A . n 
A 1 542 LEU 542 535 535 LEU LEU A . n 
A 1 543 ARG 543 536 536 ARG ARG A . n 
A 1 544 GLU 544 537 537 GLU GLU A . n 
A 1 545 HIS 545 538 538 HIS HIS A . n 
A 1 546 ASN 546 539 539 ASN ASN A . n 
A 1 547 SER 547 540 540 SER SER A . n 
A 1 548 PHE 548 541 541 PHE PHE A . n 
A 1 549 VAL 549 542 542 VAL VAL A . n 
A 1 550 GLU 550 543 543 GLU GLU A . n 
A 1 551 ARG 551 544 544 ARG ARG A . n 
A 1 552 CYS 552 545 545 CYS CYS A . n 
A 1 553 ILE 553 546 546 ILE ILE A . n 
A 1 554 ASP 554 547 547 ASP ASP A . n 
A 1 555 TRP 555 548 548 TRP TRP A . n 
A 1 556 ASN 556 549 549 ASN ASN A . n 
A 1 557 ARG 557 550 550 ARG ARG A . n 
A 1 558 GLU 558 551 551 GLU GLU A . n 
A 1 559 LEU 559 552 552 LEU LEU A . n 
A 1 560 LEU 560 553 553 LEU LEU A . n 
A 1 561 LYS 561 554 554 LYS LYS A . n 
A 1 562 ARG 562 555 555 ARG ARG A . n 
A 1 563 GLU 563 556 556 GLU GLU A . n 
A 1 564 LEU 564 557 557 LEU LEU A . n 
A 1 565 GLY 565 558 558 GLY GLY A . n 
A 1 566 LEU 566 559 559 LEU LEU A . n 
A 1 567 ALA 567 560 560 ALA ALA A . n 
A 1 568 GLU 568 561 561 GLU GLU A . n 
A 1 569 SER 569 562 562 SER SER A . n 
A 1 570 ASP 570 563 563 ASP ASP A . n 
A 1 571 ILE 571 564 564 ILE ILE A . n 
A 1 572 ILE 572 565 565 ILE ILE A . n 
A 1 573 ASP 573 566 566 ASP ASP A . n 
A 1 574 ILE 574 567 567 ILE ILE A . n 
A 1 575 PRO 575 568 568 PRO PRO A . n 
A 1 576 GLN 576 569 569 GLN GLN A . n 
A 1 577 LEU 577 570 570 LEU LEU A . n 
A 1 578 PHE 578 571 571 PHE PHE A . n 
A 1 579 LYS 579 572 572 LYS LYS A . n 
A 1 580 LEU 580 573 573 LEU LEU A . n 
A 1 581 LYS 581 574 574 LYS LYS A . n 
A 1 582 GLU 582 575 575 GLU GLU A . n 
A 1 583 PHE 583 576 576 PHE PHE A . n 
A 1 584 SER 584 577 577 SER SER A . n 
A 1 585 LYS 585 578 578 LYS LYS A . n 
A 1 586 ALA 586 579 579 ALA ALA A . n 
A 1 587 GLU 587 580 580 GLU GLU A . n 
A 1 588 ALA 588 581 581 ALA ALA A . n 
A 1 589 PHE 589 582 582 PHE PHE A . n 
A 1 590 PHE 590 583 583 PHE PHE A . n 
A 1 591 PRO 591 584 584 PRO PRO A . n 
A 1 592 ASN 592 585 585 ASN ASN A . n 
A 1 593 MET 593 586 586 MET MET A . n 
A 1 594 VAL 594 587 587 VAL VAL A . n 
A 1 595 ASN 595 588 588 ASN ASN A . n 
A 1 596 MET 596 589 589 MET MET A . n 
A 1 597 LEU 597 590 590 LEU LEU A . n 
A 1 598 VAL 598 591 591 VAL VAL A . n 
A 1 599 LEU 599 592 592 LEU LEU A . n 
A 1 600 GLY 600 593 593 GLY GLY A . n 
A 1 601 LYS 601 594 594 LYS LYS A . n 
A 1 602 HIS 602 595 595 HIS HIS A . n 
A 1 603 LEU 603 596 596 LEU LEU A . n 
A 1 604 GLY 604 597 597 GLY GLY A . n 
A 1 605 ILE 605 598 598 ILE ILE A . n 
A 1 606 PRO 606 599 599 PRO PRO A . n 
A 1 607 LYS 607 600 600 LYS LYS A . n 
A 1 608 PRO 608 601 601 PRO PRO A . n 
A 1 609 PHE 609 602 602 PHE PHE A . n 
A 1 610 GLY 610 603 603 GLY GLY A . n 
A 1 611 PRO 611 604 604 PRO PRO A . n 
A 1 612 VAL 612 605 605 VAL VAL A . n 
A 1 613 ILE 613 606 606 ILE ILE A . n 
A 1 614 ASN 614 607 607 ASN ASN A . n 
A 1 615 GLY 615 608 608 GLY GLY A . n 
A 1 616 ARG 616 609 609 ARG ARG A . n 
A 1 617 CYS 617 610 610 CYS CYS A . n 
A 1 618 CYS 618 611 611 CYS CYS A . n 
A 1 619 LEU 619 612 612 LEU LEU A . n 
A 1 620 GLU 620 613 613 GLU GLU A . n 
A 1 621 GLU 621 614 614 GLU GLU A . n 
A 1 622 LYS 622 615 615 LYS LYS A . n 
A 1 623 VAL 623 616 616 VAL VAL A . n 
A 1 624 CYS 624 617 617 CYS CYS A . n 
A 1 625 SER 625 618 618 SER SER A . n 
A 1 626 LEU 626 619 619 LEU LEU A . n 
A 1 627 LEU 627 620 620 LEU LEU A . n 
A 1 628 GLU 628 621 621 GLU GLU A . n 
A 1 629 PRO 629 622 622 PRO PRO A . n 
A 1 630 LEU 630 623 623 LEU LEU A . n 
A 1 631 GLY 631 624 624 GLY GLY A . n 
A 1 632 LEU 632 625 625 LEU LEU A . n 
A 1 633 GLN 633 626 626 GLN GLN A . n 
A 1 634 CYS 634 627 627 CYS CYS A . n 
A 1 635 THR 635 628 628 THR THR A . n 
A 1 636 PHE 636 629 629 PHE PHE A . n 
A 1 637 ILE 637 630 630 ILE ILE A . n 
A 1 638 ASN 638 631 631 ASN ASN A . n 
A 1 639 ASP 639 632 632 ASP ASP A . n 
A 1 640 PHE 640 633 633 PHE PHE A . n 
A 1 641 PHE 641 634 634 PHE PHE A . n 
A 1 642 THR 642 635 635 THR THR A . n 
A 1 643 TYR 643 636 636 TYR TYR A . n 
A 1 644 HIS 644 637 637 HIS HIS A . n 
A 1 645 ILE 645 638 638 ILE ILE A . n 
A 1 646 ARG 646 639 639 ARG ARG A . n 
A 1 647 HIS 647 640 640 HIS HIS A . n 
A 1 648 GLY 648 641 641 GLY GLY A . n 
A 1 649 GLU 649 642 642 GLU GLU A . n 
A 1 650 VAL 650 643 643 VAL VAL A . n 
A 1 651 HIS 651 644 644 HIS HIS A . n 
A 1 652 CYS 652 645 645 CYS CYS A . n 
A 1 653 GLY 653 646 646 GLY GLY A . n 
A 1 654 THR 654 647 647 THR THR A . n 
A 1 655 ASN 655 648 648 ASN ASN A . n 
A 1 656 VAL 656 649 649 VAL VAL A . n 
A 1 657 ARG 657 650 650 ARG ARG A . n 
A 1 658 ARG 658 651 651 ARG ARG A . n 
A 1 659 LYS 659 652 652 LYS LYS A . n 
A 1 660 PRO 660 653 653 PRO PRO A . n 
A 1 661 PHE 661 654 654 PHE PHE A . n 
A 1 662 SER 662 655 655 SER SER A . n 
A 1 663 PHE 663 656 656 PHE PHE A . n 
A 1 664 LYS 664 657 657 LYS LYS A . n 
A 1 665 TRP 665 658 658 TRP TRP A . n 
A 1 666 TRP 666 659 659 TRP TRP A . n 
A 1 667 ASN 667 660 660 ASN ASN A . n 
A 1 668 MET 668 661 661 MET MET A . n 
A 1 669 VAL 669 662 662 VAL VAL A . n 
A 1 670 PRO 670 663 663 PRO PRO A . n 
B 2 1   TYR 1   1   1   TYR TYR C . n 
B 2 2   GLU 2   2   2   GLU GLU C . n 
B 2 3   SER 3   3   3   SER SER C . n 
B 2 4   CYS 4   4   4   CYS CYS C . n 
B 2 5   ARG 5   5   5   ARG ARG C . n 
B 2 6   TYR 6   6   6   TYR TYR C . n 
B 2 7   ARG 7   7   7   ARG ARG C . n 
B 2 8   GLN 8   8   8   GLN GLN C . n 
B 2 9   VAL 9   9   9   VAL VAL C . n 
B 2 10  LEU 10  10  10  LEU LEU C . n 
B 2 11  GLN 11  11  11  GLN GLN C . n 
B 2 12  LEU 12  12  12  LEU LEU C . n 
B 2 13  NH2 13  13  13  NH2 UNK C . n 
C 2 1   TYR 1   1   1   TYR TYR D . n 
C 2 2   GLU 2   2   2   GLU GLU D . n 
C 2 3   SER 3   3   3   SER SER D . n 
C 2 4   CYS 4   4   4   CYS CYS D . n 
C 2 5   ARG 5   5   5   ARG ARG D . n 
C 2 6   TYR 6   6   6   TYR TYR D . n 
C 2 7   ARG 7   7   7   ARG ARG D . n 
C 2 8   GLN 8   8   8   GLN GLN D . n 
C 2 9   VAL 9   9   9   VAL VAL D . n 
C 2 10  LEU 10  10  10  LEU LEU D . n 
C 2 11  GLN 11  11  11  GLN GLN D . n 
C 2 12  LEU 12  12  12  LEU LEU D . n 
C 2 13  NH2 13  13  13  NH2 UNK D . n 
D 1 1   GLY 1   -6  ?   ?   ?   B . n 
D 1 2   PRO 2   -5  ?   ?   ?   B . n 
D 1 3   LEU 3   -4  ?   ?   ?   B . n 
D 1 4   GLY 4   -3  ?   ?   ?   B . n 
D 1 5   SER 5   -2  ?   ?   ?   B . n 
D 1 6   PRO 6   -1  ?   ?   ?   B . n 
D 1 7   GLN 7   0   ?   ?   ?   B . n 
D 1 8   MET 8   1   ?   ?   ?   B . n 
D 1 9   ALA 9   2   ?   ?   ?   B . n 
D 1 10  GLN 10  3   ?   ?   ?   B . n 
D 1 11  GLY 11  4   4   GLY GLY B . n 
D 1 12  THR 12  5   5   THR THR B . n 
D 1 13  LEU 13  6   6   LEU LEU B . n 
D 1 14  ILE 14  7   7   ILE ILE B . n 
D 1 15  ARG 15  8   8   ARG ARG B . n 
D 1 16  VAL 16  9   9   VAL VAL B . n 
D 1 17  THR 17  10  10  THR THR B . n 
D 1 18  PRO 18  11  11  PRO PRO B . n 
D 1 19  GLU 19  12  12  GLU GLU B . n 
D 1 20  GLN 20  13  13  GLN GLN B . n 
D 1 21  PRO 21  14  14  PRO PRO B . n 
D 1 22  THR 22  15  15  THR THR B . n 
D 1 23  HIS 23  16  16  HIS HIS B . n 
D 1 24  ALA 24  17  17  ALA ALA B . n 
D 1 25  VAL 25  18  18  VAL VAL B . n 
D 1 26  CYS 26  19  19  CYS CYS B . n 
D 1 27  VAL 27  20  20  VAL VAL B . n 
D 1 28  LEU 28  21  21  LEU LEU B . n 
D 1 29  GLY 29  22  22  GLY GLY B . n 
D 1 30  THR 30  23  23  THR THR B . n 
D 1 31  LEU 31  24  24  LEU LEU B . n 
D 1 32  THR 32  25  25  THR THR B . n 
D 1 33  GLN 33  26  26  GLN GLN B . n 
D 1 34  LEU 34  27  27  LEU LEU B . n 
D 1 35  ASP 35  28  28  ASP ASP B . n 
D 1 36  ILE 36  29  29  ILE ILE B . n 
D 1 37  CYS 37  30  30  CYS CYS B . n 
D 1 38  SER 38  31  31  SER SER B . n 
D 1 39  SER 39  32  32  SER SER B . n 
D 1 40  ALA 40  33  33  ALA ALA B . n 
D 1 41  PRO 41  34  34  PRO PRO B . n 
D 1 42  ASP 42  35  35  ASP ASP B . n 
D 1 43  ASP 43  36  36  ASP ASP B . n 
D 1 44  CYS 44  37  37  CYS CYS B . n 
D 1 45  THR 45  38  38  THR THR B . n 
D 1 46  SER 46  39  39  SER SER B . n 
D 1 47  PHE 47  40  40  PHE PHE B . n 
D 1 48  SER 48  41  41  SER SER B . n 
D 1 49  ILE 49  42  42  ILE ILE B . n 
D 1 50  ASN 50  43  43  ASN ASN B . n 
D 1 51  ALA 51  44  44  ALA ALA B . n 
D 1 52  SER 52  45  45  SER SER B . n 
D 1 53  PRO 53  46  46  PRO PRO B . n 
D 1 54  GLY 54  47  47  GLY GLY B . n 
D 1 55  VAL 55  48  48  VAL VAL B . n 
D 1 56  VAL 56  49  49  VAL VAL B . n 
D 1 57  VAL 57  50  50  VAL VAL B . n 
D 1 58  ASP 58  51  51  ASP ASP B . n 
D 1 59  ILE 59  52  52  ILE ILE B . n 
D 1 60  ALA 60  53  53  ALA ALA B . n 
D 1 61  HIS 61  54  ?   ?   ?   B . n 
D 1 62  SER 62  55  ?   ?   ?   B . n 
D 1 63  PRO 63  56  ?   ?   ?   B . n 
D 1 64  PRO 64  57  ?   ?   ?   B . n 
D 1 65  ALA 65  58  ?   ?   ?   B . n 
D 1 66  LYS 66  59  ?   ?   ?   B . n 
D 1 67  LYS 67  60  ?   ?   ?   B . n 
D 1 68  LYS 68  61  ?   ?   ?   B . n 
D 1 69  SER 69  62  ?   ?   ?   B . n 
D 1 70  THR 70  63  ?   ?   ?   B . n 
D 1 71  GLY 71  64  ?   ?   ?   B . n 
D 1 72  SER 72  65  ?   ?   ?   B . n 
D 1 73  SER 73  66  66  SER SER B . n 
D 1 74  THR 74  67  67  THR THR B . n 
D 1 75  TRP 75  68  68  TRP TRP B . n 
D 1 76  PRO 76  69  69  PRO PRO B . n 
D 1 77  LEU 77  70  70  LEU LEU B . n 
D 1 78  ASP 78  71  71  ASP ASP B . n 
D 1 79  PRO 79  72  72  PRO PRO B . n 
D 1 80  GLY 80  73  73  GLY GLY B . n 
D 1 81  VAL 81  74  74  VAL VAL B . n 
D 1 82  GLU 82  75  75  GLU GLU B . n 
D 1 83  VAL 83  76  76  VAL VAL B . n 
D 1 84  THR 84  77  77  THR THR B . n 
D 1 85  LEU 85  78  78  LEU LEU B . n 
D 1 86  THR 86  79  79  THR THR B . n 
D 1 87  MET 87  80  80  MET MET B . n 
D 1 88  LYS 88  81  81  LYS LYS B . n 
D 1 89  ALA 89  82  82  ALA ALA B . n 
D 1 90  ALA 90  83  83  ALA ALA B . n 
D 1 91  SER 91  84  84  SER SER B . n 
D 1 92  GLY 92  85  85  GLY GLY B . n 
D 1 93  SER 93  86  86  SER SER B . n 
D 1 94  THR 94  87  87  THR THR B . n 
D 1 95  GLY 95  88  88  GLY GLY B . n 
D 1 96  ASP 96  89  89  ASP ASP B . n 
D 1 97  GLN 97  90  90  GLN GLN B . n 
D 1 98  LYS 98  91  91  LYS LYS B . n 
D 1 99  VAL 99  92  92  VAL VAL B . n 
D 1 100 GLN 100 93  93  GLN GLN B . n 
D 1 101 ILE 101 94  94  ILE ILE B . n 
D 1 102 SER 102 95  95  SER SER B . n 
D 1 103 TYR 103 96  96  TYR TYR B . n 
D 1 104 TYR 104 97  97  TYR TYR B . n 
D 1 105 GLY 105 98  98  GLY GLY B . n 
D 1 106 PRO 106 99  99  PRO PRO B . n 
D 1 107 LYS 107 100 100 LYS LYS B . n 
D 1 108 THR 108 101 101 THR THR B . n 
D 1 109 PRO 109 102 102 PRO PRO B . n 
D 1 110 PRO 110 103 103 PRO PRO B . n 
D 1 111 VAL 111 104 104 VAL VAL B . n 
D 1 112 LYS 112 105 105 LYS LYS B . n 
D 1 113 ALA 113 106 106 ALA ALA B . n 
D 1 114 LEU 114 107 107 LEU LEU B . n 
D 1 115 LEU 115 108 108 LEU LEU B . n 
D 1 116 TYR 116 109 109 TYR TYR B . n 
D 1 117 LEU 117 110 110 LEU LEU B . n 
D 1 118 THR 118 111 111 THR THR B . n 
D 1 119 ALA 119 112 112 ALA ALA B . n 
D 1 120 VAL 120 113 113 VAL VAL B . n 
D 1 121 GLU 121 114 114 GLU GLU B . n 
D 1 122 ILE 122 115 115 ILE ILE B . n 
D 1 123 SER 123 116 116 SER SER B . n 
D 1 124 LEU 124 117 117 LEU LEU B . n 
D 1 125 CYS 125 118 118 CYS CYS B . n 
D 1 126 ALA 126 119 119 ALA ALA B . n 
D 1 127 ASP 127 120 120 ASP ASP B . n 
D 1 128 ILE 128 121 121 ILE ILE B . n 
D 1 129 THR 129 122 122 THR THR B . n 
D 1 130 ARG 130 123 123 ARG ARG B . n 
D 1 131 THR 131 124 124 THR THR B . n 
D 1 132 GLY 132 125 125 GLY GLY B . n 
D 1 133 LYS 133 126 126 LYS LYS B . n 
D 1 134 VAL 134 127 127 VAL VAL B . n 
D 1 135 LYS 135 128 ?   ?   ?   B . n 
D 1 136 PRO 136 129 ?   ?   ?   B . n 
D 1 137 THR 137 130 ?   ?   ?   B . n 
D 1 138 ARG 138 131 ?   ?   ?   B . n 
D 1 139 ALA 139 132 ?   ?   ?   B . n 
D 1 140 VAL 140 133 ?   ?   ?   B . n 
D 1 141 LYS 141 134 ?   ?   ?   B . n 
D 1 142 ASP 142 135 ?   ?   ?   B . n 
D 1 143 GLN 143 136 136 GLN GLN B . n 
D 1 144 ARG 144 137 137 ARG ARG B . n 
D 1 145 THR 145 138 138 THR THR B . n 
D 1 146 TRP 146 139 139 TRP TRP B . n 
D 1 147 THR 147 140 140 THR THR B . n 
D 1 148 TRP 148 141 141 TRP TRP B . n 
D 1 149 GLY 149 142 142 GLY GLY B . n 
D 1 150 PRO 150 143 143 PRO PRO B . n 
D 1 151 CYS 151 144 144 CYS CYS B . n 
D 1 152 GLY 152 145 145 GLY GLY B . n 
D 1 153 GLN 153 146 146 GLN GLN B . n 
D 1 154 GLY 154 147 147 GLY GLY B . n 
D 1 155 ALA 155 148 148 ALA ALA B . n 
D 1 156 ILE 156 149 149 ILE ILE B . n 
D 1 157 LEU 157 150 150 LEU LEU B . n 
D 1 158 LEU 158 151 151 LEU LEU B . n 
D 1 159 VAL 159 152 152 VAL VAL B . n 
D 1 160 ASN 160 153 153 ASN ASN B . n 
D 1 161 CYS 161 154 154 CYS CYS B . n 
D 1 162 ASP 162 155 155 ASP ASP B . n 
D 1 163 ARG 163 156 156 ARG ARG B . n 
D 1 164 ASP 164 157 157 ASP ASP B . n 
D 1 165 ASN 165 158 158 ASN ASN B . n 
D 1 166 LEU 166 159 159 LEU LEU B . n 
D 1 167 GLU 167 160 160 GLU GLU B . n 
D 1 168 SER 168 161 161 SER SER B . n 
D 1 169 SER 169 162 162 SER SER B . n 
D 1 170 ALA 170 163 163 ALA ALA B . n 
D 1 171 MET 171 164 164 MET MET B . n 
D 1 172 ASP 172 165 165 ASP ASP B . n 
D 1 173 CYS 173 166 166 CYS CYS B . n 
D 1 174 GLU 174 167 167 GLU GLU B . n 
D 1 175 ASP 175 168 168 ASP ASP B . n 
D 1 176 ASP 176 169 169 ASP ASP B . n 
D 1 177 GLU 177 170 170 GLU GLU B . n 
D 1 178 VAL 178 171 171 VAL VAL B . n 
D 1 179 LEU 179 172 172 LEU LEU B . n 
D 1 180 ASP 180 173 173 ASP ASP B . n 
D 1 181 SER 181 174 174 SER SER B . n 
D 1 182 GLU 182 175 175 GLU GLU B . n 
D 1 183 ASP 183 176 176 ASP ASP B . n 
D 1 184 LEU 184 177 177 LEU LEU B . n 
D 1 185 GLN 185 178 178 GLN GLN B . n 
D 1 186 ASP 186 179 179 ASP ASP B . n 
D 1 187 MET 187 180 180 MET MET B . n 
D 1 188 SER 188 181 181 SER SER B . n 
D 1 189 LEU 189 182 182 LEU LEU B . n 
D 1 190 MET 190 183 183 MET MET B . n 
D 1 191 THR 191 184 184 THR THR B . n 
D 1 192 LEU 192 185 185 LEU LEU B . n 
D 1 193 SER 193 186 186 SER SER B . n 
D 1 194 THR 194 187 187 THR THR B . n 
D 1 195 LYS 195 188 188 LYS LYS B . n 
D 1 196 THR 196 189 189 THR THR B . n 
D 1 197 PRO 197 190 190 PRO PRO B . n 
D 1 198 LYS 198 191 191 LYS LYS B . n 
D 1 199 ASP 199 192 192 ASP ASP B . n 
D 1 200 PHE 200 193 193 PHE PHE B . n 
D 1 201 PHE 201 194 194 PHE PHE B . n 
D 1 202 THR 202 195 195 THR THR B . n 
D 1 203 ASN 203 196 196 ASN ASN B . n 
D 1 204 HIS 204 197 197 HIS HIS B . n 
D 1 205 THR 205 198 198 THR THR B . n 
D 1 206 LEU 206 199 199 LEU LEU B . n 
D 1 207 VAL 207 200 200 VAL VAL B . n 
D 1 208 LEU 208 201 201 LEU LEU B . n 
D 1 209 HIS 209 202 202 HIS HIS B . n 
D 1 210 VAL 210 203 203 VAL VAL B . n 
D 1 211 ALA 211 204 204 ALA ALA B . n 
D 1 212 ARG 212 205 205 ARG ARG B . n 
D 1 213 SER 213 206 206 SER SER B . n 
D 1 214 GLU 214 207 207 GLU GLU B . n 
D 1 215 MET 215 208 208 MET MET B . n 
D 1 216 ASP 216 209 209 ASP ASP B . n 
D 1 217 LYS 217 210 210 LYS LYS B . n 
D 1 218 VAL 218 211 211 VAL VAL B . n 
D 1 219 ARG 219 212 212 ARG ARG B . n 
D 1 220 VAL 220 213 213 VAL VAL B . n 
D 1 221 PHE 221 214 214 PHE PHE B . n 
D 1 222 GLN 222 215 215 GLN GLN B . n 
D 1 223 ALA 223 216 216 ALA ALA B . n 
D 1 224 THR 224 217 217 THR THR B . n 
D 1 225 ARG 225 218 ?   ?   ?   B . n 
D 1 226 GLY 226 219 ?   ?   ?   B . n 
D 1 227 LYS 227 220 ?   ?   ?   B . n 
D 1 228 LEU 228 221 ?   ?   ?   B . n 
D 1 229 SER 229 222 ?   ?   ?   B . n 
D 1 230 SER 230 223 ?   ?   ?   B . n 
D 1 231 LYS 231 224 224 LYS LYS B . n 
D 1 232 CYS 232 225 225 CYS CYS B . n 
D 1 233 SER 233 226 226 SER SER B . n 
D 1 234 VAL 234 227 227 VAL VAL B . n 
D 1 235 VAL 235 228 228 VAL VAL B . n 
D 1 236 LEU 236 229 229 LEU LEU B . n 
D 1 237 GLY 237 230 230 GLY GLY B . n 
D 1 238 PRO 238 231 231 PRO PRO B . n 
D 1 239 LYS 239 232 232 LYS LYS B . n 
D 1 240 TRP 240 233 233 TRP TRP B . n 
D 1 241 PRO 241 234 234 PRO PRO B . n 
D 1 242 SER 242 235 235 SER SER B . n 
D 1 243 HIS 243 236 236 HIS HIS B . n 
D 1 244 TYR 244 237 237 TYR TYR B . n 
D 1 245 LEU 245 238 238 LEU LEU B . n 
D 1 246 MET 246 239 239 MET MET B . n 
D 1 247 VAL 247 240 240 VAL VAL B . n 
D 1 248 PRO 248 241 241 PRO PRO B . n 
D 1 249 GLY 249 242 242 GLY GLY B . n 
D 1 250 GLY 250 243 243 GLY GLY B . n 
D 1 251 LYS 251 244 244 LYS LYS B . n 
D 1 252 HIS 252 245 245 HIS HIS B . n 
D 1 253 ASN 253 246 246 ASN ASN B . n 
D 1 254 MET 254 247 247 MET MET B . n 
D 1 255 ASP 255 248 248 ASP ASP B . n 
D 1 256 PHE 256 249 249 PHE PHE B . n 
D 1 257 TYR 257 250 250 TYR TYR B . n 
D 1 258 VAL 258 251 251 VAL VAL B . n 
D 1 259 GLU 259 252 252 GLU GLU B . n 
D 1 260 ALA 260 253 253 ALA ALA B . n 
D 1 261 LEU 261 254 254 LEU LEU B . n 
D 1 262 ALA 262 255 255 ALA ALA B . n 
D 1 263 PHE 263 256 256 PHE PHE B . n 
D 1 264 PRO 264 257 257 PRO PRO B . n 
D 1 265 ASP 265 258 258 ASP ASP B . n 
D 1 266 THR 266 259 259 THR THR B . n 
D 1 267 ASP 267 260 260 ASP ASP B . n 
D 1 268 PHE 268 261 261 PHE PHE B . n 
D 1 269 PRO 269 262 262 PRO PRO B . n 
D 1 270 GLY 270 263 263 GLY GLY B . n 
D 1 271 LEU 271 264 264 LEU LEU B . n 
D 1 272 ILE 272 265 265 ILE ILE B . n 
D 1 273 THR 273 266 266 THR THR B . n 
D 1 274 LEU 274 267 267 LEU LEU B . n 
D 1 275 THR 275 268 268 THR THR B . n 
D 1 276 ILE 276 269 269 ILE ILE B . n 
D 1 277 SER 277 270 270 SER SER B . n 
D 1 278 LEU 278 271 271 LEU LEU B . n 
D 1 279 LEU 279 272 272 LEU LEU B . n 
D 1 280 ASP 280 273 273 ASP ASP B . n 
D 1 281 THR 281 274 274 THR THR B . n 
D 1 282 SER 282 275 275 SER SER B . n 
D 1 283 ASN 283 276 276 ASN ASN B . n 
D 1 284 LEU 284 277 277 LEU LEU B . n 
D 1 285 GLU 285 278 278 GLU GLU B . n 
D 1 286 LEU 286 279 279 LEU LEU B . n 
D 1 287 PRO 287 280 280 PRO PRO B . n 
D 1 288 GLU 288 281 281 GLU GLU B . n 
D 1 289 ALA 289 282 282 ALA ALA B . n 
D 1 290 VAL 290 283 283 VAL VAL B . n 
D 1 291 VAL 291 284 284 VAL VAL B . n 
D 1 292 PHE 292 285 285 PHE PHE B . n 
D 1 293 GLN 293 286 286 GLN GLN B . n 
D 1 294 ASP 294 287 287 ASP ASP B . n 
D 1 295 SER 295 288 288 SER SER B . n 
D 1 296 VAL 296 289 289 VAL VAL B . n 
D 1 297 VAL 297 290 290 VAL VAL B . n 
D 1 298 PHE 298 291 291 PHE PHE B . n 
D 1 299 ARG 299 292 292 ARG ARG B . n 
D 1 300 VAL 300 293 293 VAL VAL B . n 
D 1 301 ALA 301 294 294 ALA ALA B . n 
D 1 302 PRO 302 295 295 PRO PRO B . n 
D 1 303 TRP 303 296 296 TRP TRP B . n 
D 1 304 ILE 304 297 297 ILE ILE B . n 
D 1 305 MET 305 298 298 MET MET B . n 
D 1 306 THR 306 299 299 THR THR B . n 
D 1 307 PRO 307 300 300 PRO PRO B . n 
D 1 308 ASN 308 301 301 ASN ASN B . n 
D 1 309 THR 309 302 302 THR THR B . n 
D 1 310 GLN 310 303 303 GLN GLN B . n 
D 1 311 PRO 311 304 304 PRO PRO B . n 
D 1 312 PRO 312 305 305 PRO PRO B . n 
D 1 313 GLN 313 306 306 GLN GLN B . n 
D 1 314 GLU 314 307 307 GLU GLU B . n 
D 1 315 VAL 315 308 308 VAL VAL B . n 
D 1 316 TYR 316 309 309 TYR TYR B . n 
D 1 317 ALA 317 310 310 ALA ALA B . n 
D 1 318 CYS 318 311 311 CYS CYS B . n 
D 1 319 SER 319 312 312 SER SER B . n 
D 1 320 ILE 320 313 313 ILE ILE B . n 
D 1 321 PHE 321 314 314 PHE PHE B . n 
D 1 322 GLU 322 315 315 GLU GLU B . n 
D 1 323 ASN 323 316 316 ASN ASN B . n 
D 1 324 GLU 324 317 317 GLU GLU B . n 
D 1 325 ASP 325 318 318 ASP ASP B . n 
D 1 326 PHE 326 319 319 PHE PHE B . n 
D 1 327 LEU 327 320 320 LEU LEU B . n 
D 1 328 LYS 328 321 321 LYS LYS B . n 
D 1 329 SER 329 322 322 SER SER B . n 
D 1 330 VAL 330 323 323 VAL VAL B . n 
D 1 331 THR 331 324 324 THR THR B . n 
D 1 332 THR 332 325 325 THR THR B . n 
D 1 333 LEU 333 326 326 LEU LEU B . n 
D 1 334 ALA 334 327 327 ALA ALA B . n 
D 1 335 MET 335 328 328 MET MET B . n 
D 1 336 LYS 336 329 329 LYS LYS B . n 
D 1 337 ALA 337 330 330 ALA ALA B . n 
D 1 338 LYS 338 331 331 LYS LYS B . n 
D 1 339 CYS 339 332 332 CYS CYS B . n 
D 1 340 LYS 340 333 333 LYS LYS B . n 
D 1 341 LEU 341 334 334 LEU LEU B . n 
D 1 342 THR 342 335 335 THR THR B . n 
D 1 343 ILE 343 336 336 ILE ILE B . n 
D 1 344 CYS 344 337 337 CYS CYS B . n 
D 1 345 PRO 345 338 338 PRO PRO B . n 
D 1 346 GLU 346 339 339 GLU GLU B . n 
D 1 347 GLU 347 340 340 GLU GLU B . n 
D 1 348 GLU 348 341 341 GLU GLU B . n 
D 1 349 ASN 349 342 342 ASN ASN B . n 
D 1 350 MET 350 343 343 MET MET B . n 
D 1 351 ASP 351 344 344 ASP ASP B . n 
D 1 352 ASP 352 345 345 ASP ASP B . n 
D 1 353 GLN 353 346 346 GLN GLN B . n 
D 1 354 TRP 354 347 347 TRP TRP B . n 
D 1 355 MET 355 348 348 MET MET B . n 
D 1 356 GLN 356 349 349 GLN GLN B . n 
D 1 357 ASP 357 350 350 ASP ASP B . n 
D 1 358 GLU 358 351 351 GLU GLU B . n 
D 1 359 MET 359 352 352 MET MET B . n 
D 1 360 GLU 360 353 353 GLU GLU B . n 
D 1 361 ILE 361 354 354 ILE ILE B . n 
D 1 362 GLY 362 355 355 GLY GLY B . n 
D 1 363 TYR 363 356 356 TYR TYR B . n 
D 1 364 ILE 364 357 357 ILE ILE B . n 
D 1 365 GLN 365 358 358 GLN GLN B . n 
D 1 366 ALA 366 359 359 ALA ALA B . n 
D 1 367 PRO 367 360 360 PRO PRO B . n 
D 1 368 HIS 368 361 361 HIS HIS B . n 
D 1 369 LYS 369 362 362 LYS LYS B . n 
D 1 370 THR 370 363 363 THR THR B . n 
D 1 371 LEU 371 364 364 LEU LEU B . n 
D 1 372 PRO 372 365 365 PRO PRO B . n 
D 1 373 VAL 373 366 366 VAL VAL B . n 
D 1 374 VAL 374 367 367 VAL VAL B . n 
D 1 375 PHE 375 368 368 PHE PHE B . n 
D 1 376 ASP 376 369 369 ASP ASP B . n 
D 1 377 SER 377 370 370 SER SER B . n 
D 1 378 PRO 378 371 371 PRO PRO B . n 
D 1 379 ARG 379 372 372 ARG ARG B . n 
D 1 380 ASN 380 373 373 ASN ASN B . n 
D 1 381 ARG 381 374 374 ARG ARG B . n 
D 1 382 GLY 382 375 375 GLY GLY B . n 
D 1 383 LEU 383 376 376 LEU LEU B . n 
D 1 384 LYS 384 377 377 LYS LYS B . n 
D 1 385 GLU 385 378 378 GLU GLU B . n 
D 1 386 PHE 386 379 379 PHE PHE B . n 
D 1 387 PRO 387 380 380 PRO PRO B . n 
D 1 388 ILE 388 381 381 ILE ILE B . n 
D 1 389 LYS 389 382 382 LYS LYS B . n 
D 1 390 ARG 390 383 383 ARG ARG B . n 
D 1 391 VAL 391 384 384 VAL VAL B . n 
D 1 392 MET 392 385 385 MET MET B . n 
D 1 393 GLY 393 386 386 GLY GLY B . n 
D 1 394 PRO 394 387 387 PRO PRO B . n 
D 1 395 ASP 395 388 388 ASP ASP B . n 
D 1 396 PHE 396 389 389 PHE PHE B . n 
D 1 397 GLY 397 390 390 GLY GLY B . n 
D 1 398 TYR 398 391 391 TYR TYR B . n 
D 1 399 VAL 399 392 392 VAL VAL B . n 
D 1 400 THR 400 393 393 THR THR B . n 
D 1 401 ARG 401 394 394 ARG ARG B . n 
D 1 402 GLY 402 395 395 GLY GLY B . n 
D 1 403 PRO 403 396 396 PRO PRO B . n 
D 1 404 GLN 404 397 397 GLN GLN B . n 
D 1 405 THR 405 398 398 THR THR B . n 
D 1 406 GLY 406 399 399 GLY GLY B . n 
D 1 407 GLY 407 400 400 GLY GLY B . n 
D 1 408 ILE 408 401 401 ILE ILE B . n 
D 1 409 SER 409 402 402 SER SER B . n 
D 1 410 GLY 410 403 403 GLY GLY B . n 
D 1 411 LEU 411 404 404 LEU LEU B . n 
D 1 412 ASP 412 405 405 ASP ASP B . n 
D 1 413 SER 413 406 406 SER SER B . n 
D 1 414 PHE 414 407 407 PHE PHE B . n 
D 1 415 GLY 415 408 408 GLY GLY B . n 
D 1 416 ASN 416 409 409 ASN ASN B . n 
D 1 417 LEU 417 410 410 LEU LEU B . n 
D 1 418 GLU 418 411 411 GLU GLU B . n 
D 1 419 VAL 419 412 412 VAL VAL B . n 
D 1 420 SER 420 413 413 SER SER B . n 
D 1 421 PRO 421 414 414 PRO PRO B . n 
D 1 422 PRO 422 415 415 PRO PRO B . n 
D 1 423 VAL 423 416 416 VAL VAL B . n 
D 1 424 THR 424 417 417 THR THR B . n 
D 1 425 VAL 425 418 418 VAL VAL B . n 
D 1 426 ARG 426 419 419 ARG ARG B . n 
D 1 427 GLY 427 420 420 GLY GLY B . n 
D 1 428 LYS 428 421 421 LYS LYS B . n 
D 1 429 GLU 429 422 422 GLU GLU B . n 
D 1 430 TYR 430 423 423 TYR TYR B . n 
D 1 431 PRO 431 424 424 PRO PRO B . n 
D 1 432 LEU 432 425 425 LEU LEU B . n 
D 1 433 GLY 433 426 426 GLY GLY B . n 
D 1 434 ARG 434 427 427 ARG ARG B . n 
D 1 435 ILE 435 428 428 ILE ILE B . n 
D 1 436 LEU 436 429 429 LEU LEU B . n 
D 1 437 PHE 437 430 430 PHE PHE B . n 
D 1 438 GLY 438 431 431 GLY GLY B . n 
D 1 439 ASP 439 432 432 ASP ASP B . n 
D 1 440 SER 440 433 433 SER SER B . n 
D 1 441 CYS 441 434 434 CYS CYS B . n 
D 1 442 TYR 442 435 435 TYR TYR B . n 
D 1 443 PRO 443 436 436 PRO PRO B . n 
D 1 444 SER 444 437 437 SER SER B . n 
D 1 445 ASN 445 438 438 ASN ASN B . n 
D 1 446 ASP 446 439 439 ASP ASP B . n 
D 1 447 SER 447 440 440 SER SER B . n 
D 1 448 ARG 448 441 441 ARG ARG B . n 
D 1 449 GLN 449 442 442 GLN GLN B . n 
D 1 450 MET 450 443 443 MET MET B . n 
D 1 451 HIS 451 444 444 HIS HIS B . n 
D 1 452 GLN 452 445 445 GLN GLN B . n 
D 1 453 ALA 453 446 446 ALA ALA B . n 
D 1 454 LEU 454 447 447 LEU LEU B . n 
D 1 455 GLN 455 448 448 GLN GLN B . n 
D 1 456 ASP 456 449 449 ASP ASP B . n 
D 1 457 PHE 457 450 450 PHE PHE B . n 
D 1 458 LEU 458 451 451 LEU LEU B . n 
D 1 459 SER 459 452 452 SER SER B . n 
D 1 460 ALA 460 453 453 ALA ALA B . n 
D 1 461 GLN 461 454 454 GLN GLN B . n 
D 1 462 GLN 462 455 455 GLN GLN B . n 
D 1 463 VAL 463 456 456 VAL VAL B . n 
D 1 464 GLN 464 457 457 GLN GLN B . n 
D 1 465 ALA 465 458 458 ALA ALA B . n 
D 1 466 PRO 466 459 459 PRO PRO B . n 
D 1 467 VAL 467 460 460 VAL VAL B . n 
D 1 468 LYS 468 461 461 LYS LYS B . n 
D 1 469 LEU 469 462 462 LEU LEU B . n 
D 1 470 TYR 470 463 463 TYR TYR B . n 
D 1 471 SER 471 464 464 SER SER B . n 
D 1 472 ASP 472 465 465 ASP ASP B . n 
D 1 473 TRP 473 466 466 TRP TRP B . n 
D 1 474 LEU 474 467 467 LEU LEU B . n 
D 1 475 SER 475 468 468 SER SER B . n 
D 1 476 VAL 476 469 469 VAL VAL B . n 
D 1 477 GLY 477 470 470 GLY GLY B . n 
D 1 478 HIS 478 471 471 HIS HIS B . n 
D 1 479 VAL 479 472 472 VAL VAL B . n 
D 1 480 ASP 480 473 473 ASP ASP B . n 
D 1 481 GLU 481 474 474 GLU GLU B . n 
D 1 482 PHE 482 475 475 PHE PHE B . n 
D 1 483 LEU 483 476 476 LEU LEU B . n 
D 1 484 SER 484 477 477 SER SER B . n 
D 1 485 PHE 485 478 478 PHE PHE B . n 
D 1 486 VAL 486 479 479 VAL VAL B . n 
D 1 487 PRO 487 480 480 PRO PRO B . n 
D 1 488 ALA 488 481 481 ALA ALA B . n 
D 1 489 PRO 489 482 482 PRO PRO B . n 
D 1 490 ASP 490 483 483 ASP ASP B . n 
D 1 491 ARG 491 484 484 ARG ARG B . n 
D 1 492 LYS 492 485 485 LYS LYS B . n 
D 1 493 GLY 493 486 486 GLY GLY B . n 
D 1 494 PHE 494 487 487 PHE PHE B . n 
D 1 495 ARG 495 488 488 ARG ARG B . n 
D 1 496 LEU 496 489 489 LEU LEU B . n 
D 1 497 LEU 497 490 490 LEU LEU B . n 
D 1 498 LEU 498 491 491 LEU LEU B . n 
D 1 499 ALA 499 492 492 ALA ALA B . n 
D 1 500 SER 500 493 493 SER SER B . n 
D 1 501 PRO 501 494 494 PRO PRO B . n 
D 1 502 ARG 502 495 495 ARG ARG B . n 
D 1 503 SER 503 496 496 SER SER B . n 
D 1 504 CYS 504 497 497 CYS CYS B . n 
D 1 505 TYR 505 498 498 TYR TYR B . n 
D 1 506 LYS 506 499 499 LYS LYS B . n 
D 1 507 LEU 507 500 500 LEU LEU B . n 
D 1 508 PHE 508 501 501 PHE PHE B . n 
D 1 509 GLN 509 502 502 GLN GLN B . n 
D 1 510 GLU 510 503 503 GLU GLU B . n 
D 1 511 GLN 511 504 504 GLN GLN B . n 
D 1 512 GLN 512 505 505 GLN GLN B . n 
D 1 513 ASN 513 506 506 ASN ASN B . n 
D 1 514 GLU 514 507 507 GLU GLU B . n 
D 1 515 GLY 515 508 508 GLY GLY B . n 
D 1 516 HIS 516 509 509 HIS HIS B . n 
D 1 517 GLY 517 510 510 GLY GLY B . n 
D 1 518 GLU 518 511 511 GLU GLU B . n 
D 1 519 ALA 519 512 512 ALA ALA B . n 
D 1 520 LEU 520 513 513 LEU LEU B . n 
D 1 521 LEU 521 514 514 LEU LEU B . n 
D 1 522 PHE 522 515 515 PHE PHE B . n 
D 1 523 GLU 523 516 516 GLU GLU B . n 
D 1 524 GLY 524 517 517 GLY GLY B . n 
D 1 525 ILE 525 518 518 ILE ILE B . n 
D 1 526 LYS 526 519 519 LYS LYS B . n 
D 1 527 LYS 527 520 520 LYS LYS B . n 
D 1 528 LYS 528 521 521 LYS LYS B . n 
D 1 529 LYS 529 522 522 LYS LYS B . n 
D 1 530 GLN 530 523 523 GLN GLN B . n 
D 1 531 GLN 531 524 524 GLN GLN B . n 
D 1 532 LYS 532 525 525 LYS LYS B . n 
D 1 533 ILE 533 526 526 ILE ILE B . n 
D 1 534 LYS 534 527 527 LYS LYS B . n 
D 1 535 ASN 535 528 528 ASN ASN B . n 
D 1 536 ILE 536 529 529 ILE ILE B . n 
D 1 537 LEU 537 530 530 LEU LEU B . n 
D 1 538 SER 538 531 531 SER SER B . n 
D 1 539 ASN 539 532 532 ASN ASN B . n 
D 1 540 LYS 540 533 533 LYS LYS B . n 
D 1 541 THR 541 534 534 THR THR B . n 
D 1 542 LEU 542 535 535 LEU LEU B . n 
D 1 543 ARG 543 536 536 ARG ARG B . n 
D 1 544 GLU 544 537 537 GLU GLU B . n 
D 1 545 HIS 545 538 538 HIS HIS B . n 
D 1 546 ASN 546 539 539 ASN ASN B . n 
D 1 547 SER 547 540 540 SER SER B . n 
D 1 548 PHE 548 541 541 PHE PHE B . n 
D 1 549 VAL 549 542 542 VAL VAL B . n 
D 1 550 GLU 550 543 543 GLU GLU B . n 
D 1 551 ARG 551 544 544 ARG ARG B . n 
D 1 552 CYS 552 545 545 CYS CYS B . n 
D 1 553 ILE 553 546 546 ILE ILE B . n 
D 1 554 ASP 554 547 547 ASP ASP B . n 
D 1 555 TRP 555 548 548 TRP TRP B . n 
D 1 556 ASN 556 549 549 ASN ASN B . n 
D 1 557 ARG 557 550 550 ARG ARG B . n 
D 1 558 GLU 558 551 551 GLU GLU B . n 
D 1 559 LEU 559 552 552 LEU LEU B . n 
D 1 560 LEU 560 553 553 LEU LEU B . n 
D 1 561 LYS 561 554 554 LYS LYS B . n 
D 1 562 ARG 562 555 555 ARG ARG B . n 
D 1 563 GLU 563 556 556 GLU GLU B . n 
D 1 564 LEU 564 557 557 LEU LEU B . n 
D 1 565 GLY 565 558 558 GLY GLY B . n 
D 1 566 LEU 566 559 559 LEU LEU B . n 
D 1 567 ALA 567 560 560 ALA ALA B . n 
D 1 568 GLU 568 561 561 GLU GLU B . n 
D 1 569 SER 569 562 562 SER SER B . n 
D 1 570 ASP 570 563 563 ASP ASP B . n 
D 1 571 ILE 571 564 564 ILE ILE B . n 
D 1 572 ILE 572 565 565 ILE ILE B . n 
D 1 573 ASP 573 566 566 ASP ASP B . n 
D 1 574 ILE 574 567 567 ILE ILE B . n 
D 1 575 PRO 575 568 568 PRO PRO B . n 
D 1 576 GLN 576 569 569 GLN GLN B . n 
D 1 577 LEU 577 570 570 LEU LEU B . n 
D 1 578 PHE 578 571 571 PHE PHE B . n 
D 1 579 LYS 579 572 572 LYS LYS B . n 
D 1 580 LEU 580 573 573 LEU LEU B . n 
D 1 581 LYS 581 574 574 LYS LYS B . n 
D 1 582 GLU 582 575 575 GLU GLU B . n 
D 1 583 PHE 583 576 576 PHE PHE B . n 
D 1 584 SER 584 577 577 SER SER B . n 
D 1 585 LYS 585 578 578 LYS LYS B . n 
D 1 586 ALA 586 579 579 ALA ALA B . n 
D 1 587 GLU 587 580 580 GLU GLU B . n 
D 1 588 ALA 588 581 581 ALA ALA B . n 
D 1 589 PHE 589 582 582 PHE PHE B . n 
D 1 590 PHE 590 583 583 PHE PHE B . n 
D 1 591 PRO 591 584 584 PRO PRO B . n 
D 1 592 ASN 592 585 585 ASN ASN B . n 
D 1 593 MET 593 586 586 MET MET B . n 
D 1 594 VAL 594 587 587 VAL VAL B . n 
D 1 595 ASN 595 588 588 ASN ASN B . n 
D 1 596 MET 596 589 589 MET MET B . n 
D 1 597 LEU 597 590 590 LEU LEU B . n 
D 1 598 VAL 598 591 591 VAL VAL B . n 
D 1 599 LEU 599 592 592 LEU LEU B . n 
D 1 600 GLY 600 593 593 GLY GLY B . n 
D 1 601 LYS 601 594 594 LYS LYS B . n 
D 1 602 HIS 602 595 595 HIS HIS B . n 
D 1 603 LEU 603 596 596 LEU LEU B . n 
D 1 604 GLY 604 597 597 GLY GLY B . n 
D 1 605 ILE 605 598 598 ILE ILE B . n 
D 1 606 PRO 606 599 599 PRO PRO B . n 
D 1 607 LYS 607 600 600 LYS LYS B . n 
D 1 608 PRO 608 601 601 PRO PRO B . n 
D 1 609 PHE 609 602 602 PHE PHE B . n 
D 1 610 GLY 610 603 603 GLY GLY B . n 
D 1 611 PRO 611 604 604 PRO PRO B . n 
D 1 612 VAL 612 605 605 VAL VAL B . n 
D 1 613 ILE 613 606 606 ILE ILE B . n 
D 1 614 ASN 614 607 607 ASN ASN B . n 
D 1 615 GLY 615 608 608 GLY GLY B . n 
D 1 616 ARG 616 609 609 ARG ARG B . n 
D 1 617 CYS 617 610 610 CYS CYS B . n 
D 1 618 CYS 618 611 611 CYS CYS B . n 
D 1 619 LEU 619 612 612 LEU LEU B . n 
D 1 620 GLU 620 613 613 GLU GLU B . n 
D 1 621 GLU 621 614 614 GLU GLU B . n 
D 1 622 LYS 622 615 615 LYS LYS B . n 
D 1 623 VAL 623 616 616 VAL VAL B . n 
D 1 624 CYS 624 617 617 CYS CYS B . n 
D 1 625 SER 625 618 618 SER SER B . n 
D 1 626 LEU 626 619 619 LEU LEU B . n 
D 1 627 LEU 627 620 620 LEU LEU B . n 
D 1 628 GLU 628 621 621 GLU GLU B . n 
D 1 629 PRO 629 622 622 PRO PRO B . n 
D 1 630 LEU 630 623 623 LEU LEU B . n 
D 1 631 GLY 631 624 624 GLY GLY B . n 
D 1 632 LEU 632 625 625 LEU LEU B . n 
D 1 633 GLN 633 626 626 GLN GLN B . n 
D 1 634 CYS 634 627 627 CYS CYS B . n 
D 1 635 THR 635 628 628 THR THR B . n 
D 1 636 PHE 636 629 629 PHE PHE B . n 
D 1 637 ILE 637 630 630 ILE ILE B . n 
D 1 638 ASN 638 631 631 ASN ASN B . n 
D 1 639 ASP 639 632 632 ASP ASP B . n 
D 1 640 PHE 640 633 633 PHE PHE B . n 
D 1 641 PHE 641 634 634 PHE PHE B . n 
D 1 642 THR 642 635 635 THR THR B . n 
D 1 643 TYR 643 636 636 TYR TYR B . n 
D 1 644 HIS 644 637 637 HIS HIS B . n 
D 1 645 ILE 645 638 638 ILE ILE B . n 
D 1 646 ARG 646 639 639 ARG ARG B . n 
D 1 647 HIS 647 640 640 HIS HIS B . n 
D 1 648 GLY 648 641 641 GLY GLY B . n 
D 1 649 GLU 649 642 642 GLU GLU B . n 
D 1 650 VAL 650 643 643 VAL VAL B . n 
D 1 651 HIS 651 644 644 HIS HIS B . n 
D 1 652 CYS 652 645 645 CYS CYS B . n 
D 1 653 GLY 653 646 646 GLY GLY B . n 
D 1 654 THR 654 647 647 THR THR B . n 
D 1 655 ASN 655 648 648 ASN ASN B . n 
D 1 656 VAL 656 649 649 VAL VAL B . n 
D 1 657 ARG 657 650 650 ARG ARG B . n 
D 1 658 ARG 658 651 651 ARG ARG B . n 
D 1 659 LYS 659 652 652 LYS LYS B . n 
D 1 660 PRO 660 653 653 PRO PRO B . n 
D 1 661 PHE 661 654 654 PHE PHE B . n 
D 1 662 SER 662 655 655 SER SER B . n 
D 1 663 PHE 663 656 656 PHE PHE B . n 
D 1 664 LYS 664 657 657 LYS LYS B . n 
D 1 665 TRP 665 658 658 TRP TRP B . n 
D 1 666 TRP 666 659 659 TRP TRP B . n 
D 1 667 ASN 667 660 660 ASN ASN B . n 
D 1 668 MET 668 661 661 MET MET B . n 
D 1 669 VAL 669 662 662 VAL VAL B . n 
D 1 670 PRO 670 663 663 PRO PRO B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 CA 1 900 900 CA CA A . 
F 3 CA 1 901 901 CA CA A . 
G 3 CA 1 902 902 CA CA A . 
H 3 CA 1 903 903 CA CA A . 
I 3 CA 1 904 904 CA CA A . 
J 3 CA 1 900 900 CA CA B . 
K 3 CA 1 901 901 CA CA B . 
L 3 CA 1 902 902 CA CA B . 
M 3 CA 1 903 903 CA CA B . 
N 3 CA 1 904 904 CA CA B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R8V 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R8V 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R8V 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8R8V 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 10452 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.573 ? 14184 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.407 ? 1370  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.046 ? 1582  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 1836  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8R8V 
_struct.title                        'Human PADI4 in complex with cyclic peptide PADI4_11' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R8V 
_struct_keywords.text            'PADI4, peptidyl arginine deiminase, Cyclic Peptide, CYTOSOLIC PROTEIN' 
_struct_keywords.pdbx_keywords   'CYTOSOLIC PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 1 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
J N N 3 ? 
K N N 3 ? 
L N N 3 ? 
M N N 3 ? 
N N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP PADI4_HUMAN Q9UM07 ? 1 
;MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTM
KVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLE
SSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV
PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFL
KSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGG
ISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP
APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLA
ESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRH
GEVHCGTNVRRKPFSFKWWNMVP
;
1 
2 PDB 8R8V        8R8V   ? 2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8R8V A 8 ? 670 ? Q9UM07 1 ? 663 ? 1 663 
2 2 8R8V C 1 ? 13  ? 8R8V   1 ? 13  ? 1 13  
3 2 8R8V D 1 ? 13  ? 8R8V   1 ? 13  ? 1 13  
4 1 8R8V B 8 ? 670 ? Q9UM07 1 ? 663 ? 1 663 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8R8V GLY A 1   ? UNP Q9UM07 ?   ?   'expression tag' -6  1  
1 8R8V PRO A 2   ? UNP Q9UM07 ?   ?   'expression tag' -5  2  
1 8R8V LEU A 3   ? UNP Q9UM07 ?   ?   'expression tag' -4  3  
1 8R8V GLY A 4   ? UNP Q9UM07 ?   ?   'expression tag' -3  4  
1 8R8V SER A 5   ? UNP Q9UM07 ?   ?   'expression tag' -2  5  
1 8R8V PRO A 6   ? UNP Q9UM07 ?   ?   'expression tag' -1  6  
1 8R8V GLN A 7   ? UNP Q9UM07 ?   ?   'expression tag' 0   7  
1 8R8V ASP A 42  ? UNP Q9UM07 GLU 35  conflict         35  8  
1 8R8V SER A 62  ? UNP Q9UM07 GLY 55  variant          55  9  
1 8R8V ALA A 89  ? UNP Q9UM07 VAL 82  variant          82  10 
1 8R8V ALA A 119 ? UNP Q9UM07 GLY 112 variant          112 11 
4 8R8V GLY B 1   ? UNP Q9UM07 ?   ?   'expression tag' -6  12 
4 8R8V PRO B 2   ? UNP Q9UM07 ?   ?   'expression tag' -5  13 
4 8R8V LEU B 3   ? UNP Q9UM07 ?   ?   'expression tag' -4  14 
4 8R8V GLY B 4   ? UNP Q9UM07 ?   ?   'expression tag' -3  15 
4 8R8V SER B 5   ? UNP Q9UM07 ?   ?   'expression tag' -2  16 
4 8R8V PRO B 6   ? UNP Q9UM07 ?   ?   'expression tag' -1  17 
4 8R8V GLN B 7   ? UNP Q9UM07 ?   ?   'expression tag' 0   18 
4 8R8V ASP B 42  ? UNP Q9UM07 GLU 35  conflict         35  19 
4 8R8V SER B 62  ? UNP Q9UM07 GLY 55  variant          55  20 
4 8R8V ALA B 89  ? UNP Q9UM07 VAL 82  variant          82  21 
4 8R8V ALA B 119 ? UNP Q9UM07 GLY 112 variant          112 22 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 8650  ? 
1 MORE         -135  ? 
1 'SSA (A^2)'  53900 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 180 ? MET A 187 ? ASP A 173 MET A 180 5 ? 8  
HELX_P HELX_P2  AA2 ASP A 199 ? THR A 202 ? ASP A 192 THR A 195 5 ? 4  
HELX_P HELX_P3  AA3 ASN A 323 ? LYS A 338 ? ASN A 316 LYS A 331 1 ? 16 
HELX_P HELX_P4  AA4 PRO A 345 ? MET A 350 ? PRO A 338 MET A 343 1 ? 6  
HELX_P HELX_P5  AA5 GLU A 385 ? ARG A 390 ? GLU A 378 ARG A 383 1 ? 6  
HELX_P HELX_P6  AA6 SER A 409 ? SER A 413 ? SER A 402 SER A 406 5 ? 5  
HELX_P HELX_P7  AA7 HIS A 451 ? GLN A 461 ? HIS A 444 GLN A 454 1 ? 11 
HELX_P HELX_P8  AA8 HIS A 478 ? GLU A 481 ? HIS A 471 GLU A 474 5 ? 4  
HELX_P HELX_P9  AA9 PRO A 501 ? GLU A 514 ? PRO A 494 GLU A 507 1 ? 14 
HELX_P HELX_P10 AB1 ILE A 533 ? ASN A 539 ? ILE A 526 ASN A 532 1 ? 7  
HELX_P HELX_P11 AB2 LYS A 540 ? LEU A 564 ? LYS A 533 LEU A 557 1 ? 25 
HELX_P HELX_P12 AB3 ALA A 567 ? SER A 569 ? ALA A 560 SER A 562 5 ? 3  
HELX_P HELX_P13 AB4 GLU A 582 ? SER A 584 ? GLU A 575 SER A 577 5 ? 3  
HELX_P HELX_P14 AB5 CYS A 618 ? GLU A 628 ? CYS A 611 GLU A 621 1 ? 11 
HELX_P HELX_P15 AB6 PRO A 629 ? GLY A 631 ? PRO A 622 GLY A 624 5 ? 3  
HELX_P HELX_P16 AB7 TYR A 643 ? HIS A 647 ? TYR A 636 HIS A 640 5 ? 5  
HELX_P HELX_P17 AB8 LYS A 664 ? MET A 668 ? LYS A 657 MET A 661 5 ? 5  
HELX_P HELX_P18 AB9 GLU B 2   ? LEU B 12  ? GLU C 2   LEU C 12  1 ? 11 
HELX_P HELX_P19 AC1 GLU C 2   ? LEU C 12  ? GLU D 2   LEU D 12  1 ? 11 
HELX_P HELX_P20 AC2 ASP D 180 ? MET D 187 ? ASP B 173 MET B 180 5 ? 8  
HELX_P HELX_P21 AC3 ASP D 199 ? THR D 202 ? ASP B 192 THR B 195 5 ? 4  
HELX_P HELX_P22 AC4 ASN D 323 ? LYS D 338 ? ASN B 316 LYS B 331 1 ? 16 
HELX_P HELX_P23 AC5 PRO D 345 ? MET D 350 ? PRO B 338 MET B 343 1 ? 6  
HELX_P HELX_P24 AC6 GLU D 385 ? ARG D 390 ? GLU B 378 ARG B 383 1 ? 6  
HELX_P HELX_P25 AC7 SER D 409 ? SER D 413 ? SER B 402 SER B 406 5 ? 5  
HELX_P HELX_P26 AC8 HIS D 451 ? GLN D 461 ? HIS B 444 GLN B 454 1 ? 11 
HELX_P HELX_P27 AC9 HIS D 478 ? GLU D 481 ? HIS B 471 GLU B 474 5 ? 4  
HELX_P HELX_P28 AD1 PRO D 501 ? GLU D 514 ? PRO B 494 GLU B 507 1 ? 14 
HELX_P HELX_P29 AD2 ILE D 533 ? ASN D 539 ? ILE B 526 ASN B 532 1 ? 7  
HELX_P HELX_P30 AD3 LYS D 540 ? LEU D 564 ? LYS B 533 LEU B 557 1 ? 25 
HELX_P HELX_P31 AD4 ALA D 567 ? SER D 569 ? ALA B 560 SER B 562 5 ? 3  
HELX_P HELX_P32 AD5 GLU D 582 ? SER D 584 ? GLU B 575 SER B 577 5 ? 3  
HELX_P HELX_P33 AD6 CYS D 618 ? GLU D 628 ? CYS B 611 GLU B 621 1 ? 11 
HELX_P HELX_P34 AD7 PRO D 629 ? GLY D 631 ? PRO B 622 GLY B 624 5 ? 3  
HELX_P HELX_P35 AD8 TYR D 643 ? HIS D 647 ? TYR B 636 HIS B 640 5 ? 5  
HELX_P HELX_P36 AD9 LYS D 664 ? MET D 668 ? LYS B 657 MET B 661 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale both ? B LEU 12  C   ? ? ? 1_555 B NH2 13 N  ? ? C LEU 12  C NH2 13  1_555 ? ? ? ? ? ? ? 1.335 ? ? 
covale2  covale both ? C LEU 12  C   ? ? ? 1_555 C NH2 13 N  ? ? D LEU 12  D NH2 13  1_555 ? ? ? ? ? ? ? 1.334 ? ? 
metalc1  metalc ?    ? A ASN 160 OD1 ? ? ? 1_555 F CA  .  CA ? ? A ASN 153 A CA  901 1_555 ? ? ? ? ? ? ? 2.344 ? ? 
metalc2  metalc ?    ? A ASP 162 OD1 ? ? ? 1_555 F CA  .  CA ? ? A ASP 155 A CA  901 1_555 ? ? ? ? ? ? ? 2.238 ? ? 
metalc3  metalc ?    ? A ASP 162 OD2 ? ? ? 1_555 F CA  .  CA ? ? A ASP 155 A CA  901 1_555 ? ? ? ? ? ? ? 3.032 ? ? 
metalc4  metalc ?    ? A ASP 162 OD2 ? ? ? 1_555 G CA  .  CA ? ? A ASP 155 A CA  902 1_555 ? ? ? ? ? ? ? 2.399 ? ? 
metalc5  metalc ?    ? A ASP 164 OD2 ? ? ? 1_555 F CA  .  CA ? ? A ASP 157 A CA  901 1_555 ? ? ? ? ? ? ? 2.287 ? ? 
metalc6  metalc ?    ? A ASP 164 OD1 ? ? ? 1_555 G CA  .  CA ? ? A ASP 157 A CA  902 1_555 ? ? ? ? ? ? ? 2.304 ? ? 
metalc7  metalc ?    ? A ASP 164 OD2 ? ? ? 1_555 G CA  .  CA ? ? A ASP 157 A CA  902 1_555 ? ? ? ? ? ? ? 2.819 ? ? 
metalc8  metalc ?    ? A ASP 172 O   ? ? ? 1_555 I CA  .  CA ? ? A ASP 165 A CA  904 1_555 ? ? ? ? ? ? ? 2.265 ? ? 
metalc9  metalc ?    ? A ASP 172 OD2 ? ? ? 1_555 I CA  .  CA ? ? A ASP 165 A CA  904 1_555 ? ? ? ? ? ? ? 2.380 ? ? 
metalc10 metalc ?    ? A ASP 175 OD1 ? ? ? 1_555 I CA  .  CA ? ? A ASP 168 A CA  904 1_555 ? ? ? ? ? ? ? 3.193 ? ? 
metalc11 metalc ?    ? A GLU 177 O   ? ? ? 1_555 I CA  .  CA ? ? A GLU 170 A CA  904 1_555 ? ? ? ? ? ? ? 2.377 ? ? 
metalc12 metalc ?    ? A ASP 183 OD1 ? ? ? 1_555 F CA  .  CA ? ? A ASP 176 A CA  901 1_555 ? ? ? ? ? ? ? 2.258 ? ? 
metalc13 metalc ?    ? A ASP 186 OD2 ? ? ? 1_555 F CA  .  CA ? ? A ASP 179 A CA  901 1_555 ? ? ? ? ? ? ? 2.333 ? ? 
metalc14 metalc ?    ? A ASP 186 OD1 ? ? ? 1_555 G CA  .  CA ? ? A ASP 179 A CA  902 1_555 ? ? ? ? ? ? ? 2.886 ? ? 
metalc15 metalc ?    ? A ASP 186 OD2 ? ? ? 1_555 G CA  .  CA ? ? A ASP 179 A CA  902 1_555 ? ? ? ? ? ? ? 2.263 ? ? 
metalc16 metalc ?    ? A GLU 358 OE2 ? ? ? 1_555 H CA  .  CA ? ? A GLU 351 A CA  903 1_555 ? ? ? ? ? ? ? 2.732 ? ? 
metalc17 metalc ?    ? A GLU 360 OE1 ? ? ? 1_555 E CA  .  CA ? ? A GLU 353 A CA  900 1_555 ? ? ? ? ? ? ? 2.401 ? ? 
metalc18 metalc ?    ? A ASP 376 OD1 ? ? ? 1_555 H CA  .  CA ? ? A ASP 369 A CA  903 1_555 ? ? ? ? ? ? ? 2.375 ? ? 
metalc19 metalc ?    ? A ASP 376 OD2 ? ? ? 1_555 H CA  .  CA ? ? A ASP 369 A CA  903 1_555 ? ? ? ? ? ? ? 2.317 ? ? 
metalc20 metalc ?    ? A SER 377 O   ? ? ? 1_555 H CA  .  CA ? ? A SER 370 A CA  903 1_555 ? ? ? ? ? ? ? 3.152 ? ? 
metalc21 metalc ?    ? A ASP 395 OD1 ? ? ? 1_555 G CA  .  CA ? ? A ASP 388 A CA  902 1_555 ? ? ? ? ? ? ? 2.324 ? ? 
metalc22 metalc ?    ? A PHE 414 O   ? ? ? 1_555 E CA  .  CA ? ? A PHE 407 A CA  900 1_555 ? ? ? ? ? ? ? 3.165 ? ? 
metalc23 metalc ?    ? A LEU 417 O   ? ? ? 1_555 E CA  .  CA ? ? A LEU 410 A CA  900 1_555 ? ? ? ? ? ? ? 3.020 ? ? 
metalc24 metalc ?    ? D ASN 160 OD1 ? ? ? 1_555 K CA  .  CA ? ? B ASN 153 B CA  901 1_555 ? ? ? ? ? ? ? 2.344 ? ? 
metalc25 metalc ?    ? D ASP 162 OD1 ? ? ? 1_555 K CA  .  CA ? ? B ASP 155 B CA  901 1_555 ? ? ? ? ? ? ? 2.238 ? ? 
metalc26 metalc ?    ? D ASP 162 OD2 ? ? ? 1_555 K CA  .  CA ? ? B ASP 155 B CA  901 1_555 ? ? ? ? ? ? ? 3.032 ? ? 
metalc27 metalc ?    ? D ASP 162 OD2 ? ? ? 1_555 L CA  .  CA ? ? B ASP 155 B CA  902 1_555 ? ? ? ? ? ? ? 2.399 ? ? 
metalc28 metalc ?    ? D ASP 164 OD2 ? ? ? 1_555 K CA  .  CA ? ? B ASP 157 B CA  901 1_555 ? ? ? ? ? ? ? 2.287 ? ? 
metalc29 metalc ?    ? D ASP 164 OD1 ? ? ? 1_555 L CA  .  CA ? ? B ASP 157 B CA  902 1_555 ? ? ? ? ? ? ? 2.304 ? ? 
metalc30 metalc ?    ? D ASP 164 OD2 ? ? ? 1_555 L CA  .  CA ? ? B ASP 157 B CA  902 1_555 ? ? ? ? ? ? ? 2.819 ? ? 
metalc31 metalc ?    ? D ASP 172 O   ? ? ? 1_555 N CA  .  CA ? ? B ASP 165 B CA  904 1_555 ? ? ? ? ? ? ? 2.265 ? ? 
metalc32 metalc ?    ? D ASP 172 OD2 ? ? ? 1_555 N CA  .  CA ? ? B ASP 165 B CA  904 1_555 ? ? ? ? ? ? ? 2.380 ? ? 
metalc33 metalc ?    ? D ASP 175 OD1 ? ? ? 1_555 N CA  .  CA ? ? B ASP 168 B CA  904 1_555 ? ? ? ? ? ? ? 3.193 ? ? 
metalc34 metalc ?    ? D GLU 177 O   ? ? ? 1_555 N CA  .  CA ? ? B GLU 170 B CA  904 1_555 ? ? ? ? ? ? ? 2.377 ? ? 
metalc35 metalc ?    ? D ASP 183 OD1 ? ? ? 1_555 K CA  .  CA ? ? B ASP 176 B CA  901 1_555 ? ? ? ? ? ? ? 2.258 ? ? 
metalc36 metalc ?    ? D ASP 186 OD2 ? ? ? 1_555 K CA  .  CA ? ? B ASP 179 B CA  901 1_555 ? ? ? ? ? ? ? 2.332 ? ? 
metalc37 metalc ?    ? D ASP 186 OD1 ? ? ? 1_555 L CA  .  CA ? ? B ASP 179 B CA  902 1_555 ? ? ? ? ? ? ? 2.887 ? ? 
metalc38 metalc ?    ? D ASP 186 OD2 ? ? ? 1_555 L CA  .  CA ? ? B ASP 179 B CA  902 1_555 ? ? ? ? ? ? ? 2.264 ? ? 
metalc39 metalc ?    ? D GLU 358 OE2 ? ? ? 1_555 M CA  .  CA ? ? B GLU 351 B CA  903 1_555 ? ? ? ? ? ? ? 2.732 ? ? 
metalc40 metalc ?    ? D GLU 360 OE1 ? ? ? 1_555 J CA  .  CA ? ? B GLU 353 B CA  900 1_555 ? ? ? ? ? ? ? 2.401 ? ? 
metalc41 metalc ?    ? D ASP 376 OD1 ? ? ? 1_555 M CA  .  CA ? ? B ASP 369 B CA  903 1_555 ? ? ? ? ? ? ? 2.374 ? ? 
metalc42 metalc ?    ? D ASP 376 OD2 ? ? ? 1_555 M CA  .  CA ? ? B ASP 369 B CA  903 1_555 ? ? ? ? ? ? ? 2.317 ? ? 
metalc43 metalc ?    ? D SER 377 O   ? ? ? 1_555 M CA  .  CA ? ? B SER 370 B CA  903 1_555 ? ? ? ? ? ? ? 3.152 ? ? 
metalc44 metalc ?    ? D ASP 395 OD1 ? ? ? 1_555 L CA  .  CA ? ? B ASP 388 B CA  902 1_555 ? ? ? ? ? ? ? 2.324 ? ? 
metalc45 metalc ?    ? D PHE 414 O   ? ? ? 1_555 J CA  .  CA ? ? B PHE 407 B CA  900 1_555 ? ? ? ? ? ? ? 3.165 ? ? 
metalc46 metalc ?    ? D LEU 417 O   ? ? ? 1_555 J CA  .  CA ? ? B LEU 410 B CA  900 1_555 ? ? ? ? ? ? ? 3.020 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD1 ? A ASN 160 ? A ASN 153 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD1 ? A ASP 162 ? A ASP 155 ? 1_555 75.8  ? 
2  OD1 ? A ASN 160 ? A ASN 153 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD2 ? A ASP 162 ? A ASP 155 ? 1_555 114.2 ? 
3  OD1 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD2 ? A ASP 162 ? A ASP 155 ? 1_555 46.1  ? 
4  OD1 ? A ASN 160 ? A ASN 153 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD2 ? A ASP 164 ? A ASP 157 ? 1_555 157.5 ? 
5  OD1 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD2 ? A ASP 164 ? A ASP 157 ? 1_555 93.4  ? 
6  OD2 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD2 ? A ASP 164 ? A ASP 157 ? 1_555 67.4  ? 
7  OD1 ? A ASN 160 ? A ASN 153 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD1 ? A ASP 183 ? A ASP 176 ? 1_555 91.4  ? 
8  OD1 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD1 ? A ASP 183 ? A ASP 176 ? 1_555 153.5 ? 
9  OD2 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD1 ? A ASP 183 ? A ASP 176 ? 1_555 154.3 ? 
10 OD2 ? A ASP 164 ? A ASP 157 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD1 ? A ASP 183 ? A ASP 176 ? 1_555 90.0  ? 
11 OD1 ? A ASN 160 ? A ASN 153 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD2 ? A ASP 186 ? A ASP 179 ? 1_555 129.5 ? 
12 OD1 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD2 ? A ASP 186 ? A ASP 179 ? 1_555 105.4 ? 
13 OD2 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD2 ? A ASP 186 ? A ASP 179 ? 1_555 61.7  ? 
14 OD2 ? A ASP 164 ? A ASP 157 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD2 ? A ASP 186 ? A ASP 179 ? 1_555 72.1  ? 
15 OD1 ? A ASP 183 ? A ASP 176 ? 1_555 CA ? F CA . ? A CA 901 ? 1_555 OD2 ? A ASP 186 ? A ASP 179 ? 1_555 100.7 ? 
16 OD2 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD1 ? A ASP 164 ? A ASP 157 ? 1_555 101.2 ? 
17 OD2 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD2 ? A ASP 164 ? A ASP 157 ? 1_555 70.1  ? 
18 OD1 ? A ASP 164 ? A ASP 157 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD2 ? A ASP 164 ? A ASP 157 ? 1_555 49.5  ? 
19 OD2 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD1 ? A ASP 186 ? A ASP 179 ? 1_555 90.3  ? 
20 OD1 ? A ASP 164 ? A ASP 157 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD1 ? A ASP 186 ? A ASP 179 ? 1_555 150.4 ? 
21 OD2 ? A ASP 164 ? A ASP 157 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD1 ? A ASP 186 ? A ASP 179 ? 1_555 112.1 ? 
22 OD2 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD2 ? A ASP 186 ? A ASP 179 ? 1_555 74.2  ? 
23 OD1 ? A ASP 164 ? A ASP 157 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD2 ? A ASP 186 ? A ASP 179 ? 1_555 108.3 ? 
24 OD2 ? A ASP 164 ? A ASP 157 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD2 ? A ASP 186 ? A ASP 179 ? 1_555 63.5  ? 
25 OD1 ? A ASP 186 ? A ASP 179 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD2 ? A ASP 186 ? A ASP 179 ? 1_555 48.5  ? 
26 OD2 ? A ASP 162 ? A ASP 155 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD1 ? A ASP 395 ? A ASP 388 ? 1_555 110.3 ? 
27 OD1 ? A ASP 164 ? A ASP 157 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD1 ? A ASP 395 ? A ASP 388 ? 1_555 101.8 ? 
28 OD2 ? A ASP 164 ? A ASP 157 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD1 ? A ASP 395 ? A ASP 388 ? 1_555 148.4 ? 
29 OD1 ? A ASP 186 ? A ASP 179 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD1 ? A ASP 395 ? A ASP 388 ? 1_555 99.5  ? 
30 OD2 ? A ASP 186 ? A ASP 179 ? 1_555 CA ? G CA . ? A CA 902 ? 1_555 OD1 ? A ASP 395 ? A ASP 388 ? 1_555 148.0 ? 
31 O   ? A ASP 172 ? A ASP 165 ? 1_555 CA ? I CA . ? A CA 904 ? 1_555 OD2 ? A ASP 172 ? A ASP 165 ? 1_555 72.6  ? 
32 O   ? A ASP 172 ? A ASP 165 ? 1_555 CA ? I CA . ? A CA 904 ? 1_555 OD1 ? A ASP 175 ? A ASP 168 ? 1_555 61.9  ? 
33 OD2 ? A ASP 172 ? A ASP 165 ? 1_555 CA ? I CA . ? A CA 904 ? 1_555 OD1 ? A ASP 175 ? A ASP 168 ? 1_555 85.7  ? 
34 O   ? A ASP 172 ? A ASP 165 ? 1_555 CA ? I CA . ? A CA 904 ? 1_555 O   ? A GLU 177 ? A GLU 170 ? 1_555 150.7 ? 
35 OD2 ? A ASP 172 ? A ASP 165 ? 1_555 CA ? I CA . ? A CA 904 ? 1_555 O   ? A GLU 177 ? A GLU 170 ? 1_555 110.0 ? 
36 OD1 ? A ASP 175 ? A ASP 168 ? 1_555 CA ? I CA . ? A CA 904 ? 1_555 O   ? A GLU 177 ? A GLU 170 ? 1_555 88.9  ? 
37 OE2 ? A GLU 358 ? A GLU 351 ? 1_555 CA ? H CA . ? A CA 903 ? 1_555 OD1 ? A ASP 376 ? A ASP 369 ? 1_555 71.9  ? 
38 OE2 ? A GLU 358 ? A GLU 351 ? 1_555 CA ? H CA . ? A CA 903 ? 1_555 OD2 ? A ASP 376 ? A ASP 369 ? 1_555 114.0 ? 
39 OD1 ? A ASP 376 ? A ASP 369 ? 1_555 CA ? H CA . ? A CA 903 ? 1_555 OD2 ? A ASP 376 ? A ASP 369 ? 1_555 55.6  ? 
40 OE2 ? A GLU 358 ? A GLU 351 ? 1_555 CA ? H CA . ? A CA 903 ? 1_555 O   ? A SER 377 ? A SER 370 ? 1_555 91.2  ? 
41 OD1 ? A ASP 376 ? A ASP 369 ? 1_555 CA ? H CA . ? A CA 903 ? 1_555 O   ? A SER 377 ? A SER 370 ? 1_555 66.5  ? 
42 OD2 ? A ASP 376 ? A ASP 369 ? 1_555 CA ? H CA . ? A CA 903 ? 1_555 O   ? A SER 377 ? A SER 370 ? 1_555 100.3 ? 
43 OE1 ? A GLU 360 ? A GLU 353 ? 1_555 CA ? E CA . ? A CA 900 ? 1_555 O   ? A PHE 414 ? A PHE 407 ? 1_555 94.4  ? 
44 OE1 ? A GLU 360 ? A GLU 353 ? 1_555 CA ? E CA . ? A CA 900 ? 1_555 O   ? A LEU 417 ? A LEU 410 ? 1_555 82.6  ? 
45 O   ? A PHE 414 ? A PHE 407 ? 1_555 CA ? E CA . ? A CA 900 ? 1_555 O   ? A LEU 417 ? A LEU 410 ? 1_555 77.7  ? 
46 OD1 ? D ASN 160 ? B ASN 153 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD1 ? D ASP 162 ? B ASP 155 ? 1_555 75.8  ? 
47 OD1 ? D ASN 160 ? B ASN 153 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD2 ? D ASP 162 ? B ASP 155 ? 1_555 114.2 ? 
48 OD1 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD2 ? D ASP 162 ? B ASP 155 ? 1_555 46.1  ? 
49 OD1 ? D ASN 160 ? B ASN 153 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD2 ? D ASP 164 ? B ASP 157 ? 1_555 157.5 ? 
50 OD1 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD2 ? D ASP 164 ? B ASP 157 ? 1_555 93.4  ? 
51 OD2 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD2 ? D ASP 164 ? B ASP 157 ? 1_555 67.4  ? 
52 OD1 ? D ASN 160 ? B ASN 153 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD1 ? D ASP 183 ? B ASP 176 ? 1_555 91.4  ? 
53 OD1 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD1 ? D ASP 183 ? B ASP 176 ? 1_555 153.5 ? 
54 OD2 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD1 ? D ASP 183 ? B ASP 176 ? 1_555 154.3 ? 
55 OD2 ? D ASP 164 ? B ASP 157 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD1 ? D ASP 183 ? B ASP 176 ? 1_555 90.0  ? 
56 OD1 ? D ASN 160 ? B ASN 153 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD2 ? D ASP 186 ? B ASP 179 ? 1_555 129.6 ? 
57 OD1 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD2 ? D ASP 186 ? B ASP 179 ? 1_555 105.4 ? 
58 OD2 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD2 ? D ASP 186 ? B ASP 179 ? 1_555 61.7  ? 
59 OD2 ? D ASP 164 ? B ASP 157 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD2 ? D ASP 186 ? B ASP 179 ? 1_555 72.1  ? 
60 OD1 ? D ASP 183 ? B ASP 176 ? 1_555 CA ? K CA . ? B CA 901 ? 1_555 OD2 ? D ASP 186 ? B ASP 179 ? 1_555 100.7 ? 
61 OD2 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD1 ? D ASP 164 ? B ASP 157 ? 1_555 101.3 ? 
62 OD2 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD2 ? D ASP 164 ? B ASP 157 ? 1_555 70.1  ? 
63 OD1 ? D ASP 164 ? B ASP 157 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD2 ? D ASP 164 ? B ASP 157 ? 1_555 49.5  ? 
64 OD2 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD1 ? D ASP 186 ? B ASP 179 ? 1_555 90.3  ? 
65 OD1 ? D ASP 164 ? B ASP 157 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD1 ? D ASP 186 ? B ASP 179 ? 1_555 150.3 ? 
66 OD2 ? D ASP 164 ? B ASP 157 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD1 ? D ASP 186 ? B ASP 179 ? 1_555 112.1 ? 
67 OD2 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD2 ? D ASP 186 ? B ASP 179 ? 1_555 74.2  ? 
68 OD1 ? D ASP 164 ? B ASP 157 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD2 ? D ASP 186 ? B ASP 179 ? 1_555 108.3 ? 
69 OD2 ? D ASP 164 ? B ASP 157 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD2 ? D ASP 186 ? B ASP 179 ? 1_555 63.5  ? 
70 OD1 ? D ASP 186 ? B ASP 179 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD2 ? D ASP 186 ? B ASP 179 ? 1_555 48.5  ? 
71 OD2 ? D ASP 162 ? B ASP 155 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD1 ? D ASP 395 ? B ASP 388 ? 1_555 110.4 ? 
72 OD1 ? D ASP 164 ? B ASP 157 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD1 ? D ASP 395 ? B ASP 388 ? 1_555 101.8 ? 
73 OD2 ? D ASP 164 ? B ASP 157 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD1 ? D ASP 395 ? B ASP 388 ? 1_555 148.4 ? 
74 OD1 ? D ASP 186 ? B ASP 179 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD1 ? D ASP 395 ? B ASP 388 ? 1_555 99.5  ? 
75 OD2 ? D ASP 186 ? B ASP 179 ? 1_555 CA ? L CA . ? B CA 902 ? 1_555 OD1 ? D ASP 395 ? B ASP 388 ? 1_555 148.0 ? 
76 O   ? D ASP 172 ? B ASP 165 ? 1_555 CA ? N CA . ? B CA 904 ? 1_555 OD2 ? D ASP 172 ? B ASP 165 ? 1_555 72.6  ? 
77 O   ? D ASP 172 ? B ASP 165 ? 1_555 CA ? N CA . ? B CA 904 ? 1_555 OD1 ? D ASP 175 ? B ASP 168 ? 1_555 61.9  ? 
78 OD2 ? D ASP 172 ? B ASP 165 ? 1_555 CA ? N CA . ? B CA 904 ? 1_555 OD1 ? D ASP 175 ? B ASP 168 ? 1_555 85.7  ? 
79 O   ? D ASP 172 ? B ASP 165 ? 1_555 CA ? N CA . ? B CA 904 ? 1_555 O   ? D GLU 177 ? B GLU 170 ? 1_555 150.7 ? 
80 OD2 ? D ASP 172 ? B ASP 165 ? 1_555 CA ? N CA . ? B CA 904 ? 1_555 O   ? D GLU 177 ? B GLU 170 ? 1_555 110.0 ? 
81 OD1 ? D ASP 175 ? B ASP 168 ? 1_555 CA ? N CA . ? B CA 904 ? 1_555 O   ? D GLU 177 ? B GLU 170 ? 1_555 88.9  ? 
82 OE2 ? D GLU 358 ? B GLU 351 ? 1_555 CA ? M CA . ? B CA 903 ? 1_555 OD1 ? D ASP 376 ? B ASP 369 ? 1_555 71.8  ? 
83 OE2 ? D GLU 358 ? B GLU 351 ? 1_555 CA ? M CA . ? B CA 903 ? 1_555 OD2 ? D ASP 376 ? B ASP 369 ? 1_555 114.0 ? 
84 OD1 ? D ASP 376 ? B ASP 369 ? 1_555 CA ? M CA . ? B CA 903 ? 1_555 OD2 ? D ASP 376 ? B ASP 369 ? 1_555 55.6  ? 
85 OE2 ? D GLU 358 ? B GLU 351 ? 1_555 CA ? M CA . ? B CA 903 ? 1_555 O   ? D SER 377 ? B SER 370 ? 1_555 91.2  ? 
86 OD1 ? D ASP 376 ? B ASP 369 ? 1_555 CA ? M CA . ? B CA 903 ? 1_555 O   ? D SER 377 ? B SER 370 ? 1_555 66.5  ? 
87 OD2 ? D ASP 376 ? B ASP 369 ? 1_555 CA ? M CA . ? B CA 903 ? 1_555 O   ? D SER 377 ? B SER 370 ? 1_555 100.4 ? 
88 OE1 ? D GLU 360 ? B GLU 353 ? 1_555 CA ? J CA . ? B CA 900 ? 1_555 O   ? D PHE 414 ? B PHE 407 ? 1_555 94.4  ? 
89 OE1 ? D GLU 360 ? B GLU 353 ? 1_555 CA ? J CA . ? B CA 900 ? 1_555 O   ? D LEU 417 ? B LEU 410 ? 1_555 82.6  ? 
90 O   ? D PHE 414 ? B PHE 407 ? 1_555 CA ? J CA . ? B CA 900 ? 1_555 O   ? D LEU 417 ? B LEU 410 ? 1_555 77.8  ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NH2 B 13 ? LEU B 12 ? NH2 C 13 ? 1_555 LEU C 12 ? 1_555 . . LEU 14 NH2 None 'Terminal amidation' 
2 NH2 C 13 ? LEU C 12 ? NH2 D 13 ? 1_555 LEU D 12 ? 1_555 . . LEU 14 NH2 None 'Terminal amidation' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 6 ? 
AA4 ? 5 ? 
AA5 ? 3 ? 
AA6 ? 3 ? 
AA7 ? 3 ? 
AA8 ? 2 ? 
AA9 ? 3 ? 
AB1 ? 2 ? 
AB2 ? 2 ? 
AB3 ? 3 ? 
AB4 ? 2 ? 
AB5 ? 4 ? 
AB6 ? 5 ? 
AB7 ? 6 ? 
AB8 ? 5 ? 
AB9 ? 3 ? 
AC1 ? 3 ? 
AC2 ? 3 ? 
AC3 ? 2 ? 
AC4 ? 3 ? 
AC5 ? 2 ? 
AC6 ? 2 ? 
AC7 ? 3 ? 
AC8 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? parallel      
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? parallel      
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? parallel      
AB4 1 2 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB6 4 5 ? anti-parallel 
AB7 1 2 ? parallel      
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB7 4 5 ? anti-parallel 
AB7 5 6 ? anti-parallel 
AB8 1 2 ? parallel      
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB8 4 5 ? anti-parallel 
AB9 1 2 ? parallel      
AB9 2 3 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? parallel      
AC2 1 2 ? anti-parallel 
AC2 2 3 ? parallel      
AC3 1 2 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? parallel      
AC5 1 2 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC7 2 3 ? parallel      
AC8 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 12  ? ARG A 15  ? THR A 5   ARG A 8   
AA1 2 THR A 32  ? ASP A 35  ? THR A 25  ASP A 28  
AA1 3 VAL A 83  ? MET A 87  ? VAL A 76  MET A 80  
AA1 4 VAL A 55  ? ILE A 59  ? VAL A 48  ILE A 52  
AA2 1 THR A 22  ? VAL A 27  ? THR A 15  VAL A 20  
AA2 2 VAL A 111 ? CYS A 125 ? VAL A 104 CYS A 118 
AA2 3 GLN A 97  ? TYR A 104 ? GLN A 90  TYR A 97  
AA2 4 SER A 46  ? ALA A 51  ? SER A 39  ALA A 44  
AA2 5 TRP A 75  ? PRO A 76  ? TRP A 68  PRO A 69  
AA3 1 THR A 22  ? VAL A 27  ? THR A 15  VAL A 20  
AA3 2 VAL A 111 ? CYS A 125 ? VAL A 104 CYS A 118 
AA3 3 SER A 188 ? THR A 196 ? SER A 181 THR A 189 
AA3 4 GLY A 250 ? ALA A 260 ? GLY A 243 ALA A 253 
AA3 5 VAL A 218 ? ALA A 223 ? VAL A 211 ALA A 216 
AA3 6 SER A 233 ? LEU A 236 ? SER A 226 LEU A 229 
AA4 1 ALA A 155 ? LEU A 157 ? ALA A 148 LEU A 150 
AA4 2 ALA A 289 ? VAL A 300 ? ALA A 282 VAL A 293 
AA4 3 LEU A 271 ? ASP A 280 ? LEU A 264 ASP A 273 
AA4 4 HIS A 204 ? VAL A 210 ? HIS A 197 VAL A 203 
AA4 5 SER A 242 ? LEU A 245 ? SER A 235 LEU A 238 
AA5 1 THR A 342 ? CYS A 344 ? THR A 335 CYS A 337 
AA5 2 PRO A 312 ? CYS A 318 ? PRO A 305 CYS A 311 
AA5 3 ASN A 655 ? ARG A 658 ? ASN A 648 ARG A 651 
AA6 1 MET A 359 ? ALA A 366 ? MET A 352 ALA A 359 
AA6 2 LYS A 369 ? ASP A 376 ? LYS A 362 ASP A 369 
AA6 3 GLY A 397 ? THR A 400 ? GLY A 390 THR A 393 
AA7 1 GLU A 418 ? VAL A 419 ? GLU A 411 VAL A 412 
AA7 2 ILE A 435 ? ASP A 439 ? ILE A 428 ASP A 432 
AA7 3 VAL A 467 ? TYR A 470 ? VAL A 460 TYR A 463 
AA8 1 VAL A 423 ? VAL A 425 ? VAL A 416 VAL A 418 
AA8 2 LYS A 428 ? TYR A 430 ? LYS A 421 TYR A 423 
AA9 1 LEU A 483 ? PRO A 487 ? LEU A 476 PRO A 480 
AA9 2 PHE A 494 ? SER A 500 ? PHE A 487 SER A 493 
AA9 3 ILE A 571 ? PRO A 575 ? ILE A 564 PRO A 568 
AB1 1 LEU A 520 ? LEU A 521 ? LEU A 513 LEU A 514 
AB1 2 GLN A 531 ? LYS A 532 ? GLN A 524 LYS A 525 
AB2 1 PHE A 578 ? LEU A 580 ? PHE A 571 LEU A 573 
AB2 2 ALA A 586 ? ALA A 588 ? ALA A 579 ALA A 581 
AB3 1 LEU A 597 ? LEU A 599 ? LEU A 590 LEU A 592 
AB3 2 HIS A 602 ? PRO A 606 ? HIS A 595 PRO A 599 
AB3 3 GLN A 633 ? ILE A 637 ? GLN A 626 ILE A 630 
AB4 1 VAL A 612 ? ILE A 613 ? VAL A 605 ILE A 606 
AB4 2 ARG A 616 ? CYS A 617 ? ARG A 609 CYS A 610 
AB5 1 THR D 12  ? ARG D 15  ? THR B 5   ARG B 8   
AB5 2 THR D 32  ? ASP D 35  ? THR B 25  ASP B 28  
AB5 3 VAL D 83  ? MET D 87  ? VAL B 76  MET B 80  
AB5 4 VAL D 55  ? ILE D 59  ? VAL B 48  ILE B 52  
AB6 1 THR D 22  ? VAL D 27  ? THR B 15  VAL B 20  
AB6 2 VAL D 111 ? CYS D 125 ? VAL B 104 CYS B 118 
AB6 3 GLN D 97  ? TYR D 104 ? GLN B 90  TYR B 97  
AB6 4 SER D 46  ? ALA D 51  ? SER B 39  ALA B 44  
AB6 5 TRP D 75  ? PRO D 76  ? TRP B 68  PRO B 69  
AB7 1 THR D 22  ? VAL D 27  ? THR B 15  VAL B 20  
AB7 2 VAL D 111 ? CYS D 125 ? VAL B 104 CYS B 118 
AB7 3 SER D 188 ? THR D 196 ? SER B 181 THR B 189 
AB7 4 GLY D 250 ? ALA D 260 ? GLY B 243 ALA B 253 
AB7 5 VAL D 218 ? ALA D 223 ? VAL B 211 ALA B 216 
AB7 6 SER D 233 ? LEU D 236 ? SER B 226 LEU B 229 
AB8 1 ALA D 155 ? LEU D 157 ? ALA B 148 LEU B 150 
AB8 2 ALA D 289 ? VAL D 300 ? ALA B 282 VAL B 293 
AB8 3 LEU D 271 ? ASP D 280 ? LEU B 264 ASP B 273 
AB8 4 HIS D 204 ? VAL D 210 ? HIS B 197 VAL B 203 
AB8 5 SER D 242 ? LEU D 245 ? SER B 235 LEU B 238 
AB9 1 THR D 342 ? CYS D 344 ? THR B 335 CYS B 337 
AB9 2 PRO D 312 ? CYS D 318 ? PRO B 305 CYS B 311 
AB9 3 ASN D 655 ? ARG D 658 ? ASN B 648 ARG B 651 
AC1 1 MET D 359 ? ALA D 366 ? MET B 352 ALA B 359 
AC1 2 LYS D 369 ? ASP D 376 ? LYS B 362 ASP B 369 
AC1 3 GLY D 397 ? THR D 400 ? GLY B 390 THR B 393 
AC2 1 GLU D 418 ? VAL D 419 ? GLU B 411 VAL B 412 
AC2 2 ILE D 435 ? ASP D 439 ? ILE B 428 ASP B 432 
AC2 3 VAL D 467 ? TYR D 470 ? VAL B 460 TYR B 463 
AC3 1 VAL D 423 ? VAL D 425 ? VAL B 416 VAL B 418 
AC3 2 LYS D 428 ? TYR D 430 ? LYS B 421 TYR B 423 
AC4 1 LEU D 483 ? PRO D 487 ? LEU B 476 PRO B 480 
AC4 2 PHE D 494 ? SER D 500 ? PHE B 487 SER B 493 
AC4 3 ILE D 571 ? PRO D 575 ? ILE B 564 PRO B 568 
AC5 1 LEU D 520 ? LEU D 521 ? LEU B 513 LEU B 514 
AC5 2 GLN D 531 ? LYS D 532 ? GLN B 524 LYS B 525 
AC6 1 PHE D 578 ? LEU D 580 ? PHE B 571 LEU B 573 
AC6 2 ALA D 586 ? ALA D 588 ? ALA B 579 ALA B 581 
AC7 1 LEU D 597 ? LEU D 599 ? LEU B 590 LEU B 592 
AC7 2 HIS D 602 ? PRO D 606 ? HIS B 595 PRO B 599 
AC7 3 GLN D 633 ? ILE D 637 ? GLN B 626 ILE B 630 
AC8 1 VAL D 612 ? ILE D 613 ? VAL B 605 ILE B 606 
AC8 2 ARG D 616 ? CYS D 617 ? ARG B 609 CYS B 610 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 12  ? N THR A 5   O GLN A 33  ? O GLN A 26  
AA1 2 3 N THR A 32  ? N THR A 25  O LEU A 85  ? O LEU A 78  
AA1 3 4 O THR A 84  ? O THR A 77  N ASP A 58  ? N ASP A 51  
AA2 1 2 N THR A 22  ? N THR A 15  O TYR A 116 ? O TYR A 109 
AA2 2 3 O VAL A 111 ? O VAL A 104 N TYR A 103 ? N TYR A 96  
AA2 3 4 O GLN A 100 ? O GLN A 93  N ASN A 50  ? N ASN A 43  
AA2 4 5 N PHE A 47  ? N PHE A 40  O TRP A 75  ? O TRP A 68  
AA3 1 2 N THR A 22  ? N THR A 15  O TYR A 116 ? O TYR A 109 
AA3 2 3 N SER A 123 ? N SER A 116 O SER A 193 ? O SER A 186 
AA3 3 4 N MET A 190 ? N MET A 183 O PHE A 256 ? O PHE A 249 
AA3 4 5 O ASP A 255 ? O ASP A 248 N ALA A 223 ? N ALA A 216 
AA3 5 6 N VAL A 220 ? N VAL A 213 O VAL A 235 ? O VAL A 228 
AA4 1 2 N LEU A 157 ? N LEU A 150 O ARG A 299 ? O ARG A 292 
AA4 2 3 O ALA A 289 ? O ALA A 282 N ASP A 280 ? N ASP A 273 
AA4 3 4 O LEU A 279 ? O LEU A 272 N THR A 205 ? N THR A 198 
AA4 4 5 N LEU A 208 ? N LEU A 201 O HIS A 243 ? O HIS A 236 
AA5 1 2 O THR A 342 ? O THR A 335 N VAL A 315 ? N VAL A 308 
AA5 2 3 N TYR A 316 ? N TYR A 309 O ASN A 655 ? O ASN A 648 
AA6 1 2 N GLY A 362 ? N GLY A 355 O VAL A 373 ? O VAL A 366 
AA6 2 3 N VAL A 374 ? N VAL A 367 O GLY A 397 ? O GLY A 390 
AA7 1 2 N GLU A 418 ? N GLU A 411 O LEU A 436 ? O LEU A 429 
AA7 2 3 N ASP A 439 ? N ASP A 432 O LEU A 469 ? O LEU A 462 
AA8 1 2 N VAL A 423 ? N VAL A 416 O TYR A 430 ? O TYR A 423 
AA9 1 2 N SER A 484 ? N SER A 477 O LEU A 497 ? O LEU A 490 
AA9 2 3 N LEU A 496 ? N LEU A 489 O ILE A 572 ? O ILE A 565 
AB1 1 2 N LEU A 521 ? N LEU A 514 O GLN A 531 ? O GLN A 524 
AB2 1 2 N LYS A 579 ? N LYS A 572 O GLU A 587 ? O GLU A 580 
AB3 1 2 N LEU A 599 ? N LEU A 592 O HIS A 602 ? O HIS A 595 
AB3 2 3 N ILE A 605 ? N ILE A 598 O THR A 635 ? O THR A 628 
AB4 1 2 N ILE A 613 ? N ILE A 606 O ARG A 616 ? O ARG A 609 
AB5 1 2 N THR D 12  ? N THR B 5   O GLN D 33  ? O GLN B 26  
AB5 2 3 N THR D 32  ? N THR B 25  O LEU D 85  ? O LEU B 78  
AB5 3 4 O THR D 84  ? O THR B 77  N ASP D 58  ? N ASP B 51  
AB6 1 2 N THR D 22  ? N THR B 15  O TYR D 116 ? O TYR B 109 
AB6 2 3 O VAL D 111 ? O VAL B 104 N TYR D 103 ? N TYR B 96  
AB6 3 4 O GLN D 100 ? O GLN B 93  N ASN D 50  ? N ASN B 43  
AB6 4 5 N PHE D 47  ? N PHE B 40  O TRP D 75  ? O TRP B 68  
AB7 1 2 N THR D 22  ? N THR B 15  O TYR D 116 ? O TYR B 109 
AB7 2 3 N SER D 123 ? N SER B 116 O SER D 193 ? O SER B 186 
AB7 3 4 N MET D 190 ? N MET B 183 O PHE D 256 ? O PHE B 249 
AB7 4 5 O ASP D 255 ? O ASP B 248 N ALA D 223 ? N ALA B 216 
AB7 5 6 N VAL D 220 ? N VAL B 213 O VAL D 235 ? O VAL B 228 
AB8 1 2 N LEU D 157 ? N LEU B 150 O ARG D 299 ? O ARG B 292 
AB8 2 3 O ALA D 289 ? O ALA B 282 N ASP D 280 ? N ASP B 273 
AB8 3 4 O LEU D 279 ? O LEU B 272 N THR D 205 ? N THR B 198 
AB8 4 5 N LEU D 208 ? N LEU B 201 O HIS D 243 ? O HIS B 236 
AB9 1 2 O THR D 342 ? O THR B 335 N VAL D 315 ? N VAL B 308 
AB9 2 3 N TYR D 316 ? N TYR B 309 O ASN D 655 ? O ASN B 648 
AC1 1 2 N GLY D 362 ? N GLY B 355 O VAL D 373 ? O VAL B 366 
AC1 2 3 N VAL D 374 ? N VAL B 367 O GLY D 397 ? O GLY B 390 
AC2 1 2 N GLU D 418 ? N GLU B 411 O LEU D 436 ? O LEU B 429 
AC2 2 3 N ASP D 439 ? N ASP B 432 O LEU D 469 ? O LEU B 462 
AC3 1 2 N VAL D 423 ? N VAL B 416 O TYR D 430 ? O TYR B 423 
AC4 1 2 N SER D 484 ? N SER B 477 O LEU D 497 ? O LEU B 490 
AC4 2 3 N LEU D 496 ? N LEU B 489 O ILE D 572 ? O ILE B 565 
AC5 1 2 N LEU D 521 ? N LEU B 514 O GLN D 531 ? O GLN B 524 
AC6 1 2 N LYS D 579 ? N LYS B 572 O GLU D 587 ? O GLU B 580 
AC7 1 2 N LEU D 599 ? N LEU B 592 O HIS D 602 ? O HIS B 595 
AC7 2 3 N ILE D 605 ? N ILE B 598 O THR D 635 ? O THR B 628 
AC8 1 2 N ILE D 613 ? N ILE B 606 O ARG D 616 ? O ARG B 609 
# 
_pdbx_entry_details.entry_id                   8R8V 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 THR A 101 ? ? 66.52   156.04  
2  1 PRO A 231 ? ? -69.13  3.61    
3  1 ILE A 313 ? ? -124.11 -58.35  
4  1 GLU A 315 ? ? 35.30   57.95   
5  1 ARG A 374 ? ? -75.72  -164.92 
6  1 LEU A 376 ? ? -97.84  34.08   
7  1 LEU A 410 ? ? -161.70 89.90   
8  1 GLN A 454 ? ? -69.80  98.45   
9  1 PHE A 475 ? ? -143.16 -10.94  
10 1 ARG A 484 ? ? 60.59   -136.35 
11 1 LYS A 574 ? ? -132.54 -151.38 
12 1 THR B 101 ? ? 66.56   156.00  
13 1 PRO B 231 ? ? -69.12  3.60    
14 1 ILE B 313 ? ? -124.11 -58.34  
15 1 GLU B 315 ? ? 35.22   58.01   
16 1 ARG B 374 ? ? -75.81  -164.92 
17 1 LEU B 376 ? ? -97.81  34.10   
18 1 PHE B 407 ? ? -69.97  14.96   
19 1 LEU B 410 ? ? -161.71 89.95   
20 1 GLN B 454 ? ? -69.86  98.50   
21 1 PHE B 475 ? ? -143.14 -10.93  
22 1 ARG B 484 ? ? 60.59   -136.33 
23 1 LYS B 574 ? ? -132.52 -151.41 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8R8V 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8R8V 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.6 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               79000 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Human PADI4 in complex with cyclic peptide PADI4_11' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8R8V 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8R8V 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'FEI VITROBOT MARK III' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8R8V 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8R8V 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY -6  ? A GLY 1   
2  1 Y 1 A PRO -5  ? A PRO 2   
3  1 Y 1 A LEU -4  ? A LEU 3   
4  1 Y 1 A GLY -3  ? A GLY 4   
5  1 Y 1 A SER -2  ? A SER 5   
6  1 Y 1 A PRO -1  ? A PRO 6   
7  1 Y 1 A GLN 0   ? A GLN 7   
8  1 Y 1 A MET 1   ? A MET 8   
9  1 Y 1 A ALA 2   ? A ALA 9   
10 1 Y 1 A GLN 3   ? A GLN 10  
11 1 Y 1 A HIS 54  ? A HIS 61  
12 1 Y 1 A SER 55  ? A SER 62  
13 1 Y 1 A PRO 56  ? A PRO 63  
14 1 Y 1 A PRO 57  ? A PRO 64  
15 1 Y 1 A ALA 58  ? A ALA 65  
16 1 Y 1 A LYS 59  ? A LYS 66  
17 1 Y 1 A LYS 60  ? A LYS 67  
18 1 Y 1 A LYS 61  ? A LYS 68  
19 1 Y 1 A SER 62  ? A SER 69  
20 1 Y 1 A THR 63  ? A THR 70  
21 1 Y 1 A GLY 64  ? A GLY 71  
22 1 Y 1 A SER 65  ? A SER 72  
23 1 Y 1 A LYS 128 ? A LYS 135 
24 1 Y 1 A PRO 129 ? A PRO 136 
25 1 Y 1 A THR 130 ? A THR 137 
26 1 Y 1 A ARG 131 ? A ARG 138 
27 1 Y 1 A ALA 132 ? A ALA 139 
28 1 Y 1 A VAL 133 ? A VAL 140 
29 1 Y 1 A LYS 134 ? A LYS 141 
30 1 Y 1 A ASP 135 ? A ASP 142 
31 1 Y 1 A ARG 218 ? A ARG 225 
32 1 Y 1 A GLY 219 ? A GLY 226 
33 1 Y 1 A LYS 220 ? A LYS 227 
34 1 Y 1 A LEU 221 ? A LEU 228 
35 1 Y 1 A SER 222 ? A SER 229 
36 1 Y 1 A SER 223 ? A SER 230 
37 1 Y 1 B GLY -6  ? D GLY 1   
38 1 Y 1 B PRO -5  ? D PRO 2   
39 1 Y 1 B LEU -4  ? D LEU 3   
40 1 Y 1 B GLY -3  ? D GLY 4   
41 1 Y 1 B SER -2  ? D SER 5   
42 1 Y 1 B PRO -1  ? D PRO 6   
43 1 Y 1 B GLN 0   ? D GLN 7   
44 1 Y 1 B MET 1   ? D MET 8   
45 1 Y 1 B ALA 2   ? D ALA 9   
46 1 Y 1 B GLN 3   ? D GLN 10  
47 1 Y 1 B HIS 54  ? D HIS 61  
48 1 Y 1 B SER 55  ? D SER 62  
49 1 Y 1 B PRO 56  ? D PRO 63  
50 1 Y 1 B PRO 57  ? D PRO 64  
51 1 Y 1 B ALA 58  ? D ALA 65  
52 1 Y 1 B LYS 59  ? D LYS 66  
53 1 Y 1 B LYS 60  ? D LYS 67  
54 1 Y 1 B LYS 61  ? D LYS 68  
55 1 Y 1 B SER 62  ? D SER 69  
56 1 Y 1 B THR 63  ? D THR 70  
57 1 Y 1 B GLY 64  ? D GLY 71  
58 1 Y 1 B SER 65  ? D SER 72  
59 1 Y 1 B LYS 128 ? D LYS 135 
60 1 Y 1 B PRO 129 ? D PRO 136 
61 1 Y 1 B THR 130 ? D THR 137 
62 1 Y 1 B ARG 131 ? D ARG 138 
63 1 Y 1 B ALA 132 ? D ALA 139 
64 1 Y 1 B VAL 133 ? D VAL 140 
65 1 Y 1 B LYS 134 ? D LYS 141 
66 1 Y 1 B ASP 135 ? D ASP 142 
67 1 Y 1 B ARG 218 ? D ARG 225 
68 1 Y 1 B GLY 219 ? D GLY 226 
69 1 Y 1 B LYS 220 ? D LYS 227 
70 1 Y 1 B LEU 221 ? D LEU 228 
71 1 Y 1 B SER 222 ? D SER 229 
72 1 Y 1 B SER 223 ? D SER 230 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CA  CA   CA N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
ILE N    N  N N 159 
ILE CA   C  N S 160 
ILE C    C  N N 161 
ILE O    O  N N 162 
ILE CB   C  N S 163 
ILE CG1  C  N N 164 
ILE CG2  C  N N 165 
ILE CD1  C  N N 166 
ILE OXT  O  N N 167 
ILE H    H  N N 168 
ILE H2   H  N N 169 
ILE HA   H  N N 170 
ILE HB   H  N N 171 
ILE HG12 H  N N 172 
ILE HG13 H  N N 173 
ILE HG21 H  N N 174 
ILE HG22 H  N N 175 
ILE HG23 H  N N 176 
ILE HD11 H  N N 177 
ILE HD12 H  N N 178 
ILE HD13 H  N N 179 
ILE HXT  H  N N 180 
LEU N    N  N N 181 
LEU CA   C  N S 182 
LEU C    C  N N 183 
LEU O    O  N N 184 
LEU CB   C  N N 185 
LEU CG   C  N N 186 
LEU CD1  C  N N 187 
LEU CD2  C  N N 188 
LEU OXT  O  N N 189 
LEU H    H  N N 190 
LEU H2   H  N N 191 
LEU HA   H  N N 192 
LEU HB2  H  N N 193 
LEU HB3  H  N N 194 
LEU HG   H  N N 195 
LEU HD11 H  N N 196 
LEU HD12 H  N N 197 
LEU HD13 H  N N 198 
LEU HD21 H  N N 199 
LEU HD22 H  N N 200 
LEU HD23 H  N N 201 
LEU HXT  H  N N 202 
LYS N    N  N N 203 
LYS CA   C  N S 204 
LYS C    C  N N 205 
LYS O    O  N N 206 
LYS CB   C  N N 207 
LYS CG   C  N N 208 
LYS CD   C  N N 209 
LYS CE   C  N N 210 
LYS NZ   N  N N 211 
LYS OXT  O  N N 212 
LYS H    H  N N 213 
LYS H2   H  N N 214 
LYS HA   H  N N 215 
LYS HB2  H  N N 216 
LYS HB3  H  N N 217 
LYS HG2  H  N N 218 
LYS HG3  H  N N 219 
LYS HD2  H  N N 220 
LYS HD3  H  N N 221 
LYS HE2  H  N N 222 
LYS HE3  H  N N 223 
LYS HZ1  H  N N 224 
LYS HZ2  H  N N 225 
LYS HZ3  H  N N 226 
LYS HXT  H  N N 227 
MET N    N  N N 228 
MET CA   C  N S 229 
MET C    C  N N 230 
MET O    O  N N 231 
MET CB   C  N N 232 
MET CG   C  N N 233 
MET SD   S  N N 234 
MET CE   C  N N 235 
MET OXT  O  N N 236 
MET H    H  N N 237 
MET H2   H  N N 238 
MET HA   H  N N 239 
MET HB2  H  N N 240 
MET HB3  H  N N 241 
MET HG2  H  N N 242 
MET HG3  H  N N 243 
MET HE1  H  N N 244 
MET HE2  H  N N 245 
MET HE3  H  N N 246 
MET HXT  H  N N 247 
NH2 N    N  N N 248 
NH2 HN1  H  N N 249 
NH2 HN2  H  N N 250 
PHE N    N  N N 251 
PHE CA   C  N S 252 
PHE C    C  N N 253 
PHE O    O  N N 254 
PHE CB   C  N N 255 
PHE CG   C  Y N 256 
PHE CD1  C  Y N 257 
PHE CD2  C  Y N 258 
PHE CE1  C  Y N 259 
PHE CE2  C  Y N 260 
PHE CZ   C  Y N 261 
PHE OXT  O  N N 262 
PHE H    H  N N 263 
PHE H2   H  N N 264 
PHE HA   H  N N 265 
PHE HB2  H  N N 266 
PHE HB3  H  N N 267 
PHE HD1  H  N N 268 
PHE HD2  H  N N 269 
PHE HE1  H  N N 270 
PHE HE2  H  N N 271 
PHE HZ   H  N N 272 
PHE HXT  H  N N 273 
PRO N    N  N N 274 
PRO CA   C  N S 275 
PRO C    C  N N 276 
PRO O    O  N N 277 
PRO CB   C  N N 278 
PRO CG   C  N N 279 
PRO CD   C  N N 280 
PRO OXT  O  N N 281 
PRO H    H  N N 282 
PRO HA   H  N N 283 
PRO HB2  H  N N 284 
PRO HB3  H  N N 285 
PRO HG2  H  N N 286 
PRO HG3  H  N N 287 
PRO HD2  H  N N 288 
PRO HD3  H  N N 289 
PRO HXT  H  N N 290 
SER N    N  N N 291 
SER CA   C  N S 292 
SER C    C  N N 293 
SER O    O  N N 294 
SER CB   C  N N 295 
SER OG   O  N N 296 
SER OXT  O  N N 297 
SER H    H  N N 298 
SER H2   H  N N 299 
SER HA   H  N N 300 
SER HB2  H  N N 301 
SER HB3  H  N N 302 
SER HG   H  N N 303 
SER HXT  H  N N 304 
THR N    N  N N 305 
THR CA   C  N S 306 
THR C    C  N N 307 
THR O    O  N N 308 
THR CB   C  N R 309 
THR OG1  O  N N 310 
THR CG2  C  N N 311 
THR OXT  O  N N 312 
THR H    H  N N 313 
THR H2   H  N N 314 
THR HA   H  N N 315 
THR HB   H  N N 316 
THR HG1  H  N N 317 
THR HG21 H  N N 318 
THR HG22 H  N N 319 
THR HG23 H  N N 320 
THR HXT  H  N N 321 
TRP N    N  N N 322 
TRP CA   C  N S 323 
TRP C    C  N N 324 
TRP O    O  N N 325 
TRP CB   C  N N 326 
TRP CG   C  Y N 327 
TRP CD1  C  Y N 328 
TRP CD2  C  Y N 329 
TRP NE1  N  Y N 330 
TRP CE2  C  Y N 331 
TRP CE3  C  Y N 332 
TRP CZ2  C  Y N 333 
TRP CZ3  C  Y N 334 
TRP CH2  C  Y N 335 
TRP OXT  O  N N 336 
TRP H    H  N N 337 
TRP H2   H  N N 338 
TRP HA   H  N N 339 
TRP HB2  H  N N 340 
TRP HB3  H  N N 341 
TRP HD1  H  N N 342 
TRP HE1  H  N N 343 
TRP HE3  H  N N 344 
TRP HZ2  H  N N 345 
TRP HZ3  H  N N 346 
TRP HH2  H  N N 347 
TRP HXT  H  N N 348 
TYR N    N  N N 349 
TYR CA   C  N S 350 
TYR C    C  N N 351 
TYR O    O  N N 352 
TYR CB   C  N N 353 
TYR CG   C  Y N 354 
TYR CD1  C  Y N 355 
TYR CD2  C  Y N 356 
TYR CE1  C  Y N 357 
TYR CE2  C  Y N 358 
TYR CZ   C  Y N 359 
TYR OH   O  N N 360 
TYR OXT  O  N N 361 
TYR H    H  N N 362 
TYR H2   H  N N 363 
TYR HA   H  N N 364 
TYR HB2  H  N N 365 
TYR HB3  H  N N 366 
TYR HD1  H  N N 367 
TYR HD2  H  N N 368 
TYR HE1  H  N N 369 
TYR HE2  H  N N 370 
TYR HH   H  N N 371 
TYR HXT  H  N N 372 
VAL N    N  N N 373 
VAL CA   C  N S 374 
VAL C    C  N N 375 
VAL O    O  N N 376 
VAL CB   C  N N 377 
VAL CG1  C  N N 378 
VAL CG2  C  N N 379 
VAL OXT  O  N N 380 
VAL H    H  N N 381 
VAL H2   H  N N 382 
VAL HA   H  N N 383 
VAL HB   H  N N 384 
VAL HG11 H  N N 385 
VAL HG12 H  N N 386 
VAL HG13 H  N N 387 
VAL HG21 H  N N 388 
VAL HG22 H  N N 389 
VAL HG23 H  N N 390 
VAL HXT  H  N N 391 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NH2 N   HN1  sing N N 235 
NH2 N   HN2  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-30 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           8R8V 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'Human PADI4 in complex with cyclic peptide PADI4_11' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.15 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         28.0 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'TFS FALCON 4i (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    10 
_em_imaging_optics.energyfilter_name          'TFS Selectris' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'The Francis Crick Institute' 'United Kingdom' CC2030    1 
'The Francis Crick Institute' 'United Kingdom' FC0010129 2 
'The Francis Crick Institute' 'United Kingdom' FC001134  3 
# 
_atom_sites.entry_id                    8R8V 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CA 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . GLY A 1 11  ? 117.281 153.389 123.107 1.00 103.09 ? 4   GLY A N   1 
ATOM   2     C  CA  . GLY A 1 11  ? 116.064 153.698 122.379 1.00 103.09 ? 4   GLY A CA  1 
ATOM   3     C  C   . GLY A 1 11  ? 114.890 154.060 123.267 1.00 103.09 ? 4   GLY A C   1 
ATOM   4     O  O   . GLY A 1 11  ? 115.020 154.130 124.487 1.00 103.09 ? 4   GLY A O   1 
ATOM   5     N  N   . THR A 1 12  ? 113.737 154.298 122.644 1.00 104.05 ? 5   THR A N   1 
ATOM   6     C  CA  . THR A 1 12  ? 112.514 154.630 123.362 1.00 104.05 ? 5   THR A CA  1 
ATOM   7     C  C   . THR A 1 12  ? 111.348 153.975 122.642 1.00 104.05 ? 5   THR A C   1 
ATOM   8     O  O   . THR A 1 12  ? 111.184 154.161 121.433 1.00 104.05 ? 5   THR A O   1 
ATOM   9     C  CB  . THR A 1 12  ? 112.301 156.144 123.446 1.00 104.05 ? 5   THR A CB  1 
ATOM   10    O  OG1 . THR A 1 12  ? 113.564 156.798 123.613 1.00 104.05 ? 5   THR A OG1 1 
ATOM   11    C  CG2 . THR A 1 12  ? 111.388 156.487 124.613 1.00 104.05 ? 5   THR A CG2 1 
ATOM   12    N  N   . LEU A 1 13  ? 110.560 153.196 123.372 1.00 104.55 ? 6   LEU A N   1 
ATOM   13    C  CA  . LEU A 1 13  ? 109.422 152.488 122.802 1.00 104.55 ? 6   LEU A CA  1 
ATOM   14    C  C   . LEU A 1 13  ? 108.142 153.061 123.386 1.00 104.55 ? 6   LEU A C   1 
ATOM   15    O  O   . LEU A 1 13  ? 107.872 152.892 124.580 1.00 104.55 ? 6   LEU A O   1 
ATOM   16    C  CB  . LEU A 1 13  ? 109.503 150.989 123.079 1.00 104.55 ? 6   LEU A CB  1 
ATOM   17    C  CG  . LEU A 1 13  ? 108.501 150.116 122.320 1.00 104.55 ? 6   LEU A CG  1 
ATOM   18    C  CD1 . LEU A 1 13  ? 109.187 149.413 121.160 1.00 104.55 ? 6   LEU A CD1 1 
ATOM   19    C  CD2 . LEU A 1 13  ? 107.852 149.107 123.250 1.00 104.55 ? 6   LEU A CD2 1 
ATOM   20    N  N   . ILE A 1 14  ? 107.350 153.717 122.545 1.00 99.91  ? 7   ILE A N   1 
ATOM   21    C  CA  . ILE A 1 14  ? 106.060 154.258 122.944 1.00 99.91  ? 7   ILE A CA  1 
ATOM   22    C  C   . ILE A 1 14  ? 104.997 153.676 122.027 1.00 99.91  ? 7   ILE A C   1 
ATOM   23    O  O   . ILE A 1 14  ? 105.077 153.813 120.801 1.00 99.91  ? 7   ILE A O   1 
ATOM   24    C  CB  . ILE A 1 14  ? 106.044 155.796 122.899 1.00 99.91  ? 7   ILE A CB  1 
ATOM   25    C  CG1 . ILE A 1 14  ? 106.788 156.309 121.664 1.00 99.91  ? 7   ILE A CG1 1 
ATOM   26    C  CG2 . ILE A 1 14  ? 106.633 156.369 124.182 1.00 99.91  ? 7   ILE A CG2 1 
ATOM   27    C  CD1 . ILE A 1 14  ? 106.911 157.808 121.628 1.00 99.91  ? 7   ILE A CD1 1 
ATOM   28    N  N   . ARG A 1 15  ? 104.061 152.956 122.650 1.00 105.58 ? 8   ARG A N   1 
ATOM   29    C  CA  . ARG A 1 15  ? 102.938 152.365 121.885 1.00 105.58 ? 8   ARG A CA  1 
ATOM   30    C  C   . ARG A 1 15  ? 101.734 153.289 122.064 1.00 105.58 ? 8   ARG A C   1 
ATOM   31    O  O   . ARG A 1 15  ? 101.645 153.951 123.117 1.00 105.58 ? 8   ARG A O   1 
ATOM   32    C  CB  . ARG A 1 15  ? 102.657 150.940 122.369 1.00 105.58 ? 8   ARG A CB  1 
ATOM   33    C  CG  . ARG A 1 15  ? 102.306 150.844 123.846 1.00 105.58 ? 8   ARG A CG  1 
ATOM   34    C  CD  . ARG A 1 15  ? 102.416 149.424 124.363 1.00 105.58 ? 8   ARG A CD  1 
ATOM   35    N  NE  . ARG A 1 15  ? 103.794 148.971 124.470 1.00 105.58 ? 8   ARG A NE  1 
ATOM   36    C  CZ  . ARG A 1 15  ? 104.374 148.601 125.606 1.00 105.58 ? 8   ARG A CZ  1 
ATOM   37    N  NH1 . ARG A 1 15  ? 103.781 148.848 126.761 1.00 105.58 ? 8   ARG A NH1 1 
ATOM   38    N  NH2 . ARG A 1 15  ? 105.545 147.989 125.584 1.00 105.58 ? 8   ARG A NH2 1 
ATOM   39    N  N   . VAL A 1 16  ? 100.856 153.337 121.069 1.00 110.41 ? 9   VAL A N   1 
ATOM   40    C  CA  . VAL A 1 16  ? 99.698  154.228 121.100 1.00 110.41 ? 9   VAL A CA  1 
ATOM   41    C  C   . VAL A 1 16  ? 98.440  153.412 121.362 1.00 110.41 ? 9   VAL A C   1 
ATOM   42    O  O   . VAL A 1 16  ? 98.337  152.254 120.937 1.00 110.41 ? 9   VAL A O   1 
ATOM   43    C  CB  . VAL A 1 16  ? 99.579  155.037 119.795 1.00 110.41 ? 9   VAL A CB  1 
ATOM   44    C  CG1 . VAL A 1 16  ? 100.947 155.561 119.370 1.00 110.41 ? 9   VAL A CG1 1 
ATOM   45    C  CG2 . VAL A 1 16  ? 98.955  154.198 118.684 1.00 110.41 ? 9   VAL A CG2 1 
ATOM   46    N  N   . THR A 1 17  ? 97.505  153.994 122.110 1.00 116.54 ? 10  THR A N   1 
ATOM   47    C  CA  . THR A 1 17  ? 96.212  153.393 122.377 1.00 116.54 ? 10  THR A CA  1 
ATOM   48    C  C   . THR A 1 17  ? 95.117  154.343 121.916 1.00 116.54 ? 10  THR A C   1 
ATOM   49    O  O   . THR A 1 17  ? 95.109  155.512 122.327 1.00 116.54 ? 10  THR A O   1 
ATOM   50    C  CB  . THR A 1 17  ? 96.034  153.086 123.872 1.00 116.54 ? 10  THR A CB  1 
ATOM   51    O  OG1 . THR A 1 17  ? 95.545  154.255 124.542 1.00 116.54 ? 10  THR A OG1 1 
ATOM   52    C  CG2 . THR A 1 17  ? 97.358  152.650 124.492 1.00 116.54 ? 10  THR A CG2 1 
ATOM   53    N  N   . PRO A 1 18  ? 94.193  153.901 121.060 1.00 120.39 ? 11  PRO A N   1 
ATOM   54    C  CA  . PRO A 1 18  ? 93.112  154.798 120.621 1.00 120.39 ? 11  PRO A CA  1 
ATOM   55    C  C   . PRO A 1 18  ? 92.178  155.230 121.737 1.00 120.39 ? 11  PRO A C   1 
ATOM   56    O  O   . PRO A 1 18  ? 91.437  156.203 121.550 1.00 120.39 ? 11  PRO A O   1 
ATOM   57    C  CB  . PRO A 1 18  ? 92.365  153.965 119.568 1.00 120.39 ? 11  PRO A CB  1 
ATOM   58    C  CG  . PRO A 1 18  ? 93.327  152.887 119.166 1.00 120.39 ? 11  PRO A CG  1 
ATOM   59    C  CD  . PRO A 1 18  ? 94.141  152.595 120.384 1.00 120.39 ? 11  PRO A CD  1 
ATOM   60    N  N   . GLU A 1 19  ? 92.175  154.536 122.879 1.00 121.99 ? 12  GLU A N   1 
ATOM   61    C  CA  . GLU A 1 19  ? 91.232  154.866 123.945 1.00 121.99 ? 12  GLU A CA  1 
ATOM   62    C  C   . GLU A 1 19  ? 91.458  156.275 124.480 1.00 121.99 ? 12  GLU A C   1 
ATOM   63    O  O   . GLU A 1 19  ? 90.500  157.032 124.678 1.00 121.99 ? 12  GLU A O   1 
ATOM   64    C  CB  . GLU A 1 19  ? 91.340  153.842 125.075 1.00 121.99 ? 12  GLU A CB  1 
ATOM   65    C  CG  . GLU A 1 19  ? 90.499  154.170 126.300 1.00 121.99 ? 12  GLU A CG  1 
ATOM   66    C  CD  . GLU A 1 19  ? 90.763  153.225 127.456 1.00 121.99 ? 12  GLU A CD  1 
ATOM   67    O  OE1 . GLU A 1 19  ? 91.598  152.309 127.300 1.00 121.99 ? 12  GLU A OE1 1 
ATOM   68    O  OE2 . GLU A 1 19  ? 90.134  153.398 128.521 1.00 121.99 ? 12  GLU A OE2 1 
ATOM   69    N  N   . GLN A 1 20  ? 92.712  156.646 124.725 1.00 117.64 ? 13  GLN A N   1 
ATOM   70    C  CA  . GLN A 1 20  ? 93.035  157.967 125.245 1.00 117.64 ? 13  GLN A CA  1 
ATOM   71    C  C   . GLN A 1 20  ? 94.351  158.426 124.639 1.00 117.64 ? 13  GLN A C   1 
ATOM   72    O  O   . GLN A 1 20  ? 95.182  157.591 124.264 1.00 117.64 ? 13  GLN A O   1 
ATOM   73    C  CB  . GLN A 1 20  ? 93.123  157.962 126.781 1.00 117.64 ? 13  GLN A CB  1 
ATOM   74    C  CG  . GLN A 1 20  ? 94.457  157.493 127.361 1.00 117.64 ? 13  GLN A CG  1 
ATOM   75    C  CD  . GLN A 1 20  ? 94.827  156.069 126.973 1.00 117.64 ? 13  GLN A CD  1 
ATOM   76    O  OE1 . GLN A 1 20  ? 94.007  155.315 126.446 1.00 117.64 ? 13  GLN A OE1 1 
ATOM   77    N  NE2 . GLN A 1 20  ? 96.073  155.695 127.238 1.00 117.64 ? 13  GLN A NE2 1 
ATOM   78    N  N   . PRO A 1 21  ? 94.566  159.734 124.517 1.00 110.09 ? 14  PRO A N   1 
ATOM   79    C  CA  . PRO A 1 21  ? 95.848  160.225 124.002 1.00 110.09 ? 14  PRO A CA  1 
ATOM   80    C  C   . PRO A 1 21  ? 96.980  159.954 124.980 1.00 110.09 ? 14  PRO A C   1 
ATOM   81    O  O   . PRO A 1 21  ? 96.780  159.807 126.187 1.00 110.09 ? 14  PRO A O   1 
ATOM   82    C  CB  . PRO A 1 21  ? 95.611  161.729 123.827 1.00 110.09 ? 14  PRO A CB  1 
ATOM   83    C  CG  . PRO A 1 21  ? 94.511  162.048 124.779 1.00 110.09 ? 14  PRO A CG  1 
ATOM   84    C  CD  . PRO A 1 21  ? 93.630  160.834 124.808 1.00 110.09 ? 14  PRO A CD  1 
ATOM   85    N  N   . THR A 1 22  ? 98.190  159.888 124.433 1.00 101.87 ? 15  THR A N   1 
ATOM   86    C  CA  . THR A 1 22  ? 99.381  159.539 125.193 1.00 101.87 ? 15  THR A CA  1 
ATOM   87    C  C   . THR A 1 22  ? 100.374 160.691 125.176 1.00 101.87 ? 15  THR A C   1 
ATOM   88    O  O   . THR A 1 22  ? 100.629 161.289 124.127 1.00 101.87 ? 15  THR A O   1 
ATOM   89    C  CB  . THR A 1 22  ? 100.045 158.279 124.629 1.00 101.87 ? 15  THR A CB  1 
ATOM   90    O  OG1 . THR A 1 22  ? 99.059  157.254 124.456 1.00 101.87 ? 15  THR A OG1 1 
ATOM   91    C  CG2 . THR A 1 22  ? 101.127 157.778 125.571 1.00 101.87 ? 15  THR A CG2 1 
ATOM   92    N  N   . HIS A 1 23  ? 100.931 160.996 126.344 1.00 99.72  ? 16  HIS A N   1 
ATOM   93    C  CA  . HIS A 1 23  ? 101.980 161.995 126.491 1.00 99.72  ? 16  HIS A CA  1 
ATOM   94    C  C   . HIS A 1 23  ? 103.306 161.284 126.719 1.00 99.72  ? 16  HIS A C   1 
ATOM   95    O  O   . HIS A 1 23  ? 103.404 160.413 127.590 1.00 99.72  ? 16  HIS A O   1 
ATOM   96    C  CB  . HIS A 1 23  ? 101.683 162.942 127.657 1.00 99.72  ? 16  HIS A CB  1 
ATOM   97    C  CG  . HIS A 1 23  ? 100.629 163.961 127.358 1.00 99.72  ? 16  HIS A CG  1 
ATOM   98    N  ND1 . HIS A 1 23  ? 100.902 165.309 127.272 1.00 99.72  ? 16  HIS A ND1 1 
ATOM   99    C  CD2 . HIS A 1 23  ? 99.301  163.831 127.132 1.00 99.72  ? 16  HIS A CD2 1 
ATOM   100   C  CE1 . HIS A 1 23  ? 99.787  165.965 127.002 1.00 99.72  ? 16  HIS A CE1 1 
ATOM   101   N  NE2 . HIS A 1 23  ? 98.801  165.091 126.912 1.00 99.72  ? 16  HIS A NE2 1 
ATOM   102   N  N   . ALA A 1 24  ? 104.319 161.650 125.938 1.00 85.43  ? 17  ALA A N   1 
ATOM   103   C  CA  . ALA A 1 24  ? 105.624 161.016 126.027 1.00 85.43  ? 17  ALA A CA  1 
ATOM   104   C  C   . ALA A 1 24  ? 106.710 162.044 125.756 1.00 85.43  ? 17  ALA A C   1 
ATOM   105   O  O   . ALA A 1 24  ? 106.475 163.074 125.120 1.00 85.43  ? 17  ALA A O   1 
ATOM   106   C  CB  . ALA A 1 24  ? 105.749 159.844 125.048 1.00 85.43  ? 17  ALA A CB  1 
ATOM   107   N  N   . VAL A 1 25  ? 107.910 161.748 126.247 1.00 77.67  ? 18  VAL A N   1 
ATOM   108   C  CA  . VAL A 1 25  ? 109.074 162.612 126.083 1.00 77.67  ? 18  VAL A CA  1 
ATOM   109   C  C   . VAL A 1 25  ? 110.064 161.922 125.156 1.00 77.67  ? 18  VAL A C   1 
ATOM   110   O  O   . VAL A 1 25  ? 110.453 160.772 125.391 1.00 77.67  ? 18  VAL A O   1 
ATOM   111   C  CB  . VAL A 1 25  ? 109.721 162.953 127.438 1.00 77.67  ? 18  VAL A CB  1 
ATOM   112   C  CG1 . VAL A 1 25  ? 109.934 161.697 128.270 1.00 77.67  ? 18  VAL A CG1 1 
ATOM   113   C  CG2 . VAL A 1 25  ? 111.037 163.678 127.223 1.00 77.67  ? 18  VAL A CG2 1 
ATOM   114   N  N   . CYS A 1 26  ? 110.459 162.620 124.095 1.00 79.55  ? 19  CYS A N   1 
ATOM   115   C  CA  . CYS A 1 26  ? 111.416 162.109 123.122 1.00 79.55  ? 19  CYS A CA  1 
ATOM   116   C  C   . CYS A 1 26  ? 112.687 162.943 123.212 1.00 79.55  ? 19  CYS A C   1 
ATOM   117   O  O   . CYS A 1 26  ? 112.703 164.103 122.790 1.00 79.55  ? 19  CYS A O   1 
ATOM   118   C  CB  . CYS A 1 26  ? 110.833 162.149 121.709 1.00 79.55  ? 19  CYS A CB  1 
ATOM   119   S  SG  . CYS A 1 26  ? 111.899 161.460 120.425 1.00 79.55  ? 19  CYS A SG  1 
ATOM   120   N  N   . VAL A 1 27  ? 113.743 162.354 123.762 1.00 70.20  ? 20  VAL A N   1 
ATOM   121   C  CA  . VAL A 1 27  ? 115.008 163.050 123.959 1.00 70.20  ? 20  VAL A CA  1 
ATOM   122   C  C   . VAL A 1 27  ? 115.732 163.138 122.625 1.00 70.20  ? 20  VAL A C   1 
ATOM   123   O  O   . VAL A 1 27  ? 115.851 162.139 121.907 1.00 70.20  ? 20  VAL A O   1 
ATOM   124   C  CB  . VAL A 1 27  ? 115.872 162.336 125.008 1.00 70.20  ? 20  VAL A CB  1 
ATOM   125   C  CG1 . VAL A 1 27  ? 117.081 163.182 125.354 1.00 70.20  ? 20  VAL A CG1 1 
ATOM   126   C  CG2 . VAL A 1 27  ? 115.055 162.035 126.250 1.00 70.20  ? 20  VAL A CG2 1 
ATOM   127   N  N   . LEU A 1 28  ? 116.210 164.333 122.291 1.00 77.81  ? 21  LEU A N   1 
ATOM   128   C  CA  . LEU A 1 28  ? 116.913 164.533 121.032 1.00 77.81  ? 21  LEU A CA  1 
ATOM   129   C  C   . LEU A 1 28  ? 118.222 163.751 121.039 1.00 77.81  ? 21  LEU A C   1 
ATOM   130   O  O   . LEU A 1 28  ? 118.981 163.798 122.011 1.00 77.81  ? 21  LEU A O   1 
ATOM   131   C  CB  . LEU A 1 28  ? 117.178 166.022 120.809 1.00 77.81  ? 21  LEU A CB  1 
ATOM   132   C  CG  . LEU A 1 28  ? 117.777 166.481 119.478 1.00 77.81  ? 21  LEU A CG  1 
ATOM   133   C  CD1 . LEU A 1 28  ? 117.344 165.587 118.324 1.00 77.81  ? 21  LEU A CD1 1 
ATOM   134   C  CD2 . LEU A 1 28  ? 117.401 167.928 119.206 1.00 77.81  ? 21  LEU A CD2 1 
ATOM   135   N  N   . GLY A 1 29  ? 118.483 163.031 119.950 1.00 83.32  ? 22  GLY A N   1 
ATOM   136   C  CA  . GLY A 1 29  ? 119.646 162.175 119.837 1.00 83.32  ? 22  GLY A CA  1 
ATOM   137   C  C   . GLY A 1 29  ? 119.372 160.712 120.103 1.00 83.32  ? 22  GLY A C   1 
ATOM   138   O  O   . GLY A 1 29  ? 120.318 159.914 120.112 1.00 83.32  ? 22  GLY A O   1 
ATOM   139   N  N   . THR A 1 30  ? 118.116 160.333 120.324 1.00 88.37  ? 23  THR A N   1 
ATOM   140   C  CA  . THR A 1 30  ? 117.740 158.956 120.607 1.00 88.37  ? 23  THR A CA  1 
ATOM   141   C  C   . THR A 1 30  ? 116.659 158.522 119.627 1.00 88.37  ? 23  THR A C   1 
ATOM   142   O  O   . THR A 1 30  ? 115.664 159.231 119.442 1.00 88.37  ? 23  THR A O   1 
ATOM   143   C  CB  . THR A 1 30  ? 117.245 158.812 122.050 1.00 88.37  ? 23  THR A CB  1 
ATOM   144   O  OG1 . THR A 1 30  ? 118.368 158.706 122.933 1.00 88.37  ? 23  THR A OG1 1 
ATOM   145   C  CG2 . THR A 1 30  ? 116.374 157.578 122.203 1.00 88.37  ? 23  THR A CG2 1 
ATOM   146   N  N   . LEU A 1 31  ? 116.855 157.364 119.001 1.00 95.53  ? 24  LEU A N   1 
ATOM   147   C  CA  . LEU A 1 31  ? 115.867 156.816 118.080 1.00 95.53  ? 24  LEU A CA  1 
ATOM   148   C  C   . LEU A 1 31  ? 114.666 156.317 118.873 1.00 95.53  ? 24  LEU A C   1 
ATOM   149   O  O   . LEU A 1 31  ? 114.827 155.623 119.883 1.00 95.53  ? 24  LEU A O   1 
ATOM   150   C  CB  . LEU A 1 31  ? 116.465 155.684 117.247 1.00 95.53  ? 24  LEU A CB  1 
ATOM   151   C  CG  . LEU A 1 31  ? 117.891 155.822 116.706 1.00 95.53  ? 24  LEU A CG  1 
ATOM   152   C  CD1 . LEU A 1 31  ? 118.920 155.301 117.701 1.00 95.53  ? 24  LEU A CD1 1 
ATOM   153   C  CD2 . LEU A 1 31  ? 118.022 155.103 115.371 1.00 95.53  ? 24  LEU A CD2 1 
ATOM   154   N  N   . THR A 1 32  ? 113.465 156.665 118.419 1.00 100.17 ? 25  THR A N   1 
ATOM   155   C  CA  . THR A 1 32  ? 112.228 156.290 119.094 1.00 100.17 ? 25  THR A CA  1 
ATOM   156   C  C   . THR A 1 32  ? 111.345 155.516 118.127 1.00 100.17 ? 25  THR A C   1 
ATOM   157   O  O   . THR A 1 32  ? 110.906 156.060 117.108 1.00 100.17 ? 25  THR A O   1 
ATOM   158   C  CB  . THR A 1 32  ? 111.497 157.526 119.619 1.00 100.17 ? 25  THR A CB  1 
ATOM   159   O  OG1 . THR A 1 32  ? 112.357 158.246 120.510 1.00 100.17 ? 25  THR A OG1 1 
ATOM   160   C  CG2 . THR A 1 32  ? 110.241 157.121 120.362 1.00 100.17 ? 25  THR A CG2 1 
ATOM   161   N  N   . GLN A 1 33  ? 111.072 154.256 118.451 1.00 100.84 ? 26  GLN A N   1 
ATOM   162   C  CA  . GLN A 1 33  ? 110.234 153.408 117.618 1.00 100.84 ? 26  GLN A CA  1 
ATOM   163   C  C   . GLN A 1 33  ? 108.825 153.331 118.192 1.00 100.84 ? 26  GLN A C   1 
ATOM   164   O  O   . GLN A 1 33  ? 108.631 153.277 119.409 1.00 100.84 ? 26  GLN A O   1 
ATOM   165   C  CB  . GLN A 1 33  ? 110.812 151.995 117.490 1.00 100.84 ? 26  GLN A CB  1 
ATOM   166   C  CG  . GLN A 1 33  ? 112.131 151.875 116.725 1.00 100.84 ? 26  GLN A CG  1 
ATOM   167   C  CD  . GLN A 1 33  ? 112.698 150.465 116.688 1.00 100.84 ? 26  GLN A CD  1 
ATOM   168   O  OE1 . GLN A 1 33  ? 113.453 150.101 115.787 1.00 100.84 ? 26  GLN A OE1 1 
ATOM   169   N  NE2 . GLN A 1 33  ? 112.333 149.661 117.680 1.00 100.84 ? 26  GLN A NE2 1 
ATOM   170   N  N   . LEU A 1 34  ? 107.841 153.324 117.299 1.00 105.90 ? 27  LEU A N   1 
ATOM   171   C  CA  . LEU A 1 34  ? 106.434 153.226 117.677 1.00 105.90 ? 27  LEU A CA  1 
ATOM   172   C  C   . LEU A 1 34  ? 105.962 151.792 117.473 1.00 105.90 ? 27  LEU A C   1 
ATOM   173   O  O   . LEU A 1 34  ? 105.966 151.284 116.347 1.00 105.90 ? 27  LEU A O   1 
ATOM   174   C  CB  . LEU A 1 34  ? 105.572 154.197 116.874 1.00 105.90 ? 27  LEU A CB  1 
ATOM   175   C  CG  . LEU A 1 34  ? 105.912 155.682 116.960 1.00 105.90 ? 27  LEU A CG  1 
ATOM   176   C  CD1 . LEU A 1 34  ? 105.548 156.385 115.670 1.00 105.90 ? 27  LEU A CD1 1 
ATOM   177   C  CD2 . LEU A 1 34  ? 105.182 156.307 118.131 1.00 105.90 ? 27  LEU A CD2 1 
ATOM   178   N  N   . ASP A 1 35  ? 105.550 151.148 118.561 1.00 113.25 ? 28  ASP A N   1 
ATOM   179   C  CA  . ASP A 1 35  ? 104.906 149.845 118.481 1.00 113.25 ? 28  ASP A CA  1 
ATOM   180   C  C   . ASP A 1 35  ? 103.432 150.060 118.161 1.00 113.25 ? 28  ASP A C   1 
ATOM   181   O  O   . ASP A 1 35  ? 102.704 150.671 118.950 1.00 113.25 ? 28  ASP A O   1 
ATOM   182   C  CB  . ASP A 1 35  ? 105.080 149.085 119.794 1.00 113.25 ? 28  ASP A CB  1 
ATOM   183   C  CG  . ASP A 1 35  ? 104.592 147.653 119.711 1.00 113.25 ? 28  ASP A CG  1 
ATOM   184   O  OD1 . ASP A 1 35  ? 104.180 147.223 118.615 1.00 113.25 ? 28  ASP A OD1 1 
ATOM   185   O  OD2 . ASP A 1 35  ? 104.619 146.954 120.747 1.00 113.25 ? 28  ASP A OD2 1 
ATOM   186   N  N   . ILE A 1 36  ? 102.991 149.563 117.007 1.00 119.28 ? 29  ILE A N   1 
ATOM   187   C  CA  . ILE A 1 36  ? 101.678 149.924 116.487 1.00 119.28 ? 29  ILE A CA  1 
ATOM   188   C  C   . ILE A 1 36  ? 100.793 148.686 116.375 1.00 119.28 ? 29  ILE A C   1 
ATOM   189   O  O   . ILE A 1 36  ? 99.748  148.707 115.715 1.00 119.28 ? 29  ILE A O   1 
ATOM   190   C  CB  . ILE A 1 36  ? 101.826 150.651 115.135 1.00 119.28 ? 29  ILE A CB  1 
ATOM   191   C  CG1 . ILE A 1 36  ? 100.554 151.428 114.786 1.00 119.28 ? 29  ILE A CG1 1 
ATOM   192   C  CG2 . ILE A 1 36  ? 102.206 149.672 114.031 1.00 119.28 ? 29  ILE A CG2 1 
ATOM   193   C  CD1 . ILE A 1 36  ? 100.599 152.085 113.439 1.00 119.28 ? 29  ILE A CD1 1 
ATOM   194   N  N   . CYS A 1 37  ? 101.186 147.602 117.043 1.00 124.10 ? 30  CYS A N   1 
ATOM   195   C  CA  . CYS A 1 37  ? 100.370 146.397 117.076 1.00 124.10 ? 30  CYS A CA  1 
ATOM   196   C  C   . CYS A 1 37  ? 99.944  145.975 118.473 1.00 124.10 ? 30  CYS A C   1 
ATOM   197   O  O   . CYS A 1 37  ? 99.085  145.095 118.592 1.00 124.10 ? 30  CYS A O   1 
ATOM   198   C  CB  . CYS A 1 37  ? 101.105 145.222 116.410 1.00 124.10 ? 30  CYS A CB  1 
ATOM   199   S  SG  . CYS A 1 37  ? 102.872 145.130 116.759 1.00 124.10 ? 30  CYS A SG  1 
ATOM   200   N  N   . SER A 1 38  ? 100.513 146.567 119.525 1.00 121.16 ? 31  SER A N   1 
ATOM   201   C  CA  . SER A 1 38  ? 100.138 146.181 120.882 1.00 121.16 ? 31  SER A CA  1 
ATOM   202   C  C   . SER A 1 38  ? 98.678  146.509 121.172 1.00 121.16 ? 31  SER A C   1 
ATOM   203   O  O   . SER A 1 38  ? 97.968  145.711 121.795 1.00 121.16 ? 31  SER A O   1 
ATOM   204   C  CB  . SER A 1 38  ? 101.053 146.869 121.894 1.00 121.16 ? 31  SER A CB  1 
ATOM   205   O  OG  . SER A 1 38  ? 102.413 146.571 121.635 1.00 121.16 ? 31  SER A OG  1 
ATOM   206   N  N   . SER A 1 39  ? 98.210  147.677 120.730 1.00 128.95 ? 32  SER A N   1 
ATOM   207   C  CA  . SER A 1 39  ? 96.853  148.127 121.012 1.00 128.95 ? 32  SER A CA  1 
ATOM   208   C  C   . SER A 1 39  ? 96.012  148.281 119.750 1.00 128.95 ? 32  SER A C   1 
ATOM   209   O  O   . SER A 1 39  ? 94.989  148.971 119.772 1.00 128.95 ? 32  SER A O   1 
ATOM   210   C  CB  . SER A 1 39  ? 96.884  149.443 121.790 1.00 128.95 ? 32  SER A CB  1 
ATOM   211   O  OG  . SER A 1 39  ? 95.575  149.857 122.142 1.00 128.95 ? 32  SER A OG  1 
ATOM   212   N  N   . ALA A 1 40  ? 96.467  147.674 118.648 1.00 134.38 ? 33  ALA A N   1 
ATOM   213   C  CA  . ALA A 1 40  ? 95.759  147.817 117.353 1.00 134.38 ? 33  ALA A CA  1 
ATOM   214   C  C   . ALA A 1 40  ? 94.389  147.133 117.420 1.00 134.38 ? 33  ALA A C   1 
ATOM   215   O  O   . ALA A 1 40  ? 94.282  146.083 118.084 1.00 134.38 ? 33  ALA A O   1 
ATOM   216   C  CB  . ALA A 1 40  ? 96.606  147.243 116.243 1.00 134.38 ? 33  ALA A CB  1 
ATOM   217   N  N   . PRO A 1 41  ? 93.344  147.675 116.756 1.00 143.50 ? 34  PRO A N   1 
ATOM   218   C  CA  . PRO A 1 41  ? 92.026  147.032 116.733 1.00 143.50 ? 34  PRO A CA  1 
ATOM   219   C  C   . PRO A 1 41  ? 92.128  145.602 116.186 1.00 143.50 ? 34  PRO A C   1 
ATOM   220   O  O   . PRO A 1 41  ? 92.838  145.397 115.218 1.00 143.50 ? 34  PRO A O   1 
ATOM   221   C  CB  . PRO A 1 41  ? 91.213  147.906 115.768 1.00 143.50 ? 34  PRO A CB  1 
ATOM   222   C  CG  . PRO A 1 41  ? 91.829  149.281 115.903 1.00 143.50 ? 34  PRO A CG  1 
ATOM   223   C  CD  . PRO A 1 41  ? 93.313  149.027 116.061 1.00 143.50 ? 34  PRO A CD  1 
ATOM   224   N  N   . ASP A 1 42  ? 91.427  144.656 116.817 1.00 149.65 ? 35  ASP A N   1 
ATOM   225   C  CA  . ASP A 1 42  ? 91.488  143.234 116.384 1.00 149.65 ? 35  ASP A CA  1 
ATOM   226   C  C   . ASP A 1 42  ? 91.025  143.120 114.928 1.00 149.65 ? 35  ASP A C   1 
ATOM   227   O  O   . ASP A 1 42  ? 91.742  142.481 114.134 1.00 149.65 ? 35  ASP A O   1 
ATOM   228   C  CB  . ASP A 1 42  ? 90.665  142.337 117.313 1.00 149.65 ? 35  ASP A CB  1 
ATOM   229   C  CG  . ASP A 1 42  ? 89.223  142.790 117.462 1.00 149.65 ? 35  ASP A CG  1 
ATOM   230   O  OD1 . ASP A 1 42  ? 89.012  143.926 117.929 1.00 149.65 ? 35  ASP A OD1 1 
ATOM   231   O  OD2 . ASP A 1 42  ? 88.323  142.005 117.101 1.00 149.65 ? 35  ASP A OD2 1 
ATOM   232   N  N   . ASP A 1 43  ? 89.878  143.718 114.593 1.00 152.04 ? 36  ASP A N   1 
ATOM   233   C  CA  . ASP A 1 43  ? 89.340  143.603 113.243 1.00 152.04 ? 36  ASP A CA  1 
ATOM   234   C  C   . ASP A 1 43  ? 90.065  144.481 112.230 1.00 152.04 ? 36  ASP A C   1 
ATOM   235   O  O   . ASP A 1 43  ? 89.687  144.477 111.054 1.00 152.04 ? 36  ASP A O   1 
ATOM   236   C  CB  . ASP A 1 43  ? 87.848  143.946 113.245 1.00 152.04 ? 36  ASP A CB  1 
ATOM   237   C  CG  . ASP A 1 43  ? 87.557  145.276 113.913 1.00 152.04 ? 36  ASP A CG  1 
ATOM   238   O  OD1 . ASP A 1 43  ? 87.865  145.418 115.115 1.00 152.04 ? 36  ASP A OD1 1 
ATOM   239   O  OD2 . ASP A 1 43  ? 87.021  146.178 113.236 1.00 152.04 ? 36  ASP A OD2 1 
ATOM   240   N  N   . CYS A 1 44  ? 91.084  145.225 112.648 1.00 148.73 ? 37  CYS A N   1 
ATOM   241   C  CA  . CYS A 1 44  ? 91.772  146.136 111.747 1.00 148.73 ? 37  CYS A CA  1 
ATOM   242   C  C   . CYS A 1 44  ? 92.644  145.377 110.750 1.00 148.73 ? 37  CYS A C   1 
ATOM   243   O  O   . CYS A 1 44  ? 93.048  144.233 110.974 1.00 148.73 ? 37  CYS A O   1 
ATOM   244   C  CB  . CYS A 1 44  ? 92.629  147.122 112.534 1.00 148.73 ? 37  CYS A CB  1 
ATOM   245   S  SG  . CYS A 1 44  ? 93.449  148.341 111.500 1.00 148.73 ? 37  CYS A SG  1 
ATOM   246   N  N   . THR A 1 45  ? 92.935  146.042 109.630 1.00 147.17 ? 38  THR A N   1 
ATOM   247   C  CA  . THR A 1 45  ? 93.775  145.474 108.580 1.00 147.17 ? 38  THR A CA  1 
ATOM   248   C  C   . THR A 1 45  ? 94.866  146.405 108.066 1.00 147.17 ? 38  THR A C   1 
ATOM   249   O  O   . THR A 1 45  ? 95.857  145.905 107.520 1.00 147.17 ? 38  THR A O   1 
ATOM   250   C  CB  . THR A 1 45  ? 92.918  145.029 107.384 1.00 147.17 ? 38  THR A CB  1 
ATOM   251   O  OG1 . THR A 1 45  ? 92.123  146.129 106.925 1.00 147.17 ? 38  THR A OG1 1 
ATOM   252   C  CG2 . THR A 1 45  ? 92.010  143.870 107.770 1.00 147.17 ? 38  THR A CG2 1 
ATOM   253   N  N   . SER A 1 46  ? 94.732  147.722 108.216 1.00 143.80 ? 39  SER A N   1 
ATOM   254   C  CA  . SER A 1 46  ? 95.704  148.656 107.663 1.00 143.80 ? 39  SER A CA  1 
ATOM   255   C  C   . SER A 1 46  ? 95.731  149.919 108.513 1.00 143.80 ? 39  SER A C   1 
ATOM   256   O  O   . SER A 1 46  ? 94.851  150.152 109.346 1.00 143.80 ? 39  SER A O   1 
ATOM   257   C  CB  . SER A 1 46  ? 95.387  148.991 106.202 1.00 143.80 ? 39  SER A CB  1 
ATOM   258   O  OG  . SER A 1 46  ? 95.445  147.833 105.387 1.00 143.80 ? 39  SER A OG  1 
ATOM   259   N  N   . PHE A 1 47  ? 96.757  150.741 108.291 1.00 137.59 ? 40  PHE A N   1 
ATOM   260   C  CA  . PHE A 1 47  ? 96.927  151.967 109.057 1.00 137.59 ? 40  PHE A CA  1 
ATOM   261   C  C   . PHE A 1 47  ? 97.586  153.033 108.194 1.00 137.59 ? 40  PHE A C   1 
ATOM   262   O  O   . PHE A 1 47  ? 98.224  152.739 107.179 1.00 137.59 ? 40  PHE A O   1 
ATOM   263   C  CB  . PHE A 1 47  ? 97.758  151.732 110.326 1.00 137.59 ? 40  PHE A CB  1 
ATOM   264   C  CG  . PHE A 1 47  ? 99.222  151.498 110.063 1.00 137.59 ? 40  PHE A CG  1 
ATOM   265   C  CD1 . PHE A 1 47  ? 99.698  150.224 109.809 1.00 137.59 ? 40  PHE A CD1 1 
ATOM   266   C  CD2 . PHE A 1 47  ? 100.122 152.552 110.075 1.00 137.59 ? 40  PHE A CD2 1 
ATOM   267   C  CE1 . PHE A 1 47  ? 101.041 150.006 109.571 1.00 137.59 ? 40  PHE A CE1 1 
ATOM   268   C  CE2 . PHE A 1 47  ? 101.465 152.339 109.838 1.00 137.59 ? 40  PHE A CE2 1 
ATOM   269   C  CZ  . PHE A 1 47  ? 101.925 151.064 109.585 1.00 137.59 ? 40  PHE A CZ  1 
ATOM   270   N  N   . SER A 1 48  ? 97.423  154.284 108.622 1.00 135.15 ? 41  SER A N   1 
ATOM   271   C  CA  . SER A 1 48  ? 98.073  155.431 108.003 1.00 135.15 ? 41  SER A CA  1 
ATOM   272   C  C   . SER A 1 48  ? 98.545  156.381 109.096 1.00 135.15 ? 41  SER A C   1 
ATOM   273   O  O   . SER A 1 48  ? 97.982  156.412 110.193 1.00 135.15 ? 41  SER A O   1 
ATOM   274   C  CB  . SER A 1 48  ? 97.134  156.164 107.035 1.00 135.15 ? 41  SER A CB  1 
ATOM   275   O  OG  . SER A 1 48  ? 97.083  155.509 105.780 1.00 135.15 ? 41  SER A OG  1 
ATOM   276   N  N   . ILE A 1 49  ? 99.581  157.159 108.787 1.00 128.63 ? 42  ILE A N   1 
ATOM   277   C  CA  . ILE A 1 49  ? 100.211 158.062 109.748 1.00 128.63 ? 42  ILE A CA  1 
ATOM   278   C  C   . ILE A 1 49  ? 100.249 159.460 109.147 1.00 128.63 ? 42  ILE A C   1 
ATOM   279   O  O   . ILE A 1 49  ? 100.628 159.624 107.981 1.00 128.63 ? 42  ILE A O   1 
ATOM   280   C  CB  . ILE A 1 49  ? 101.635 157.610 110.117 1.00 128.63 ? 42  ILE A CB  1 
ATOM   281   C  CG1 . ILE A 1 49  ? 101.692 156.094 110.325 1.00 128.63 ? 42  ILE A CG1 1 
ATOM   282   C  CG2 . ILE A 1 49  ? 102.128 158.352 111.352 1.00 128.63 ? 42  ILE A CG2 1 
ATOM   283   C  CD1 . ILE A 1 49  ? 101.317 155.649 111.718 1.00 128.63 ? 42  ILE A CD1 1 
ATOM   284   N  N   . ASN A 1 50  ? 99.861  160.464 109.934 1.00 121.61 ? 43  ASN A N   1 
ATOM   285   C  CA  . ASN A 1 50  ? 100.075 161.862 109.570 1.00 121.61 ? 43  ASN A CA  1 
ATOM   286   C  C   . ASN A 1 50  ? 100.622 162.614 110.778 1.00 121.61 ? 43  ASN A C   1 
ATOM   287   O  O   . ASN A 1 50  ? 100.048 162.550 111.871 1.00 121.61 ? 43  ASN A O   1 
ATOM   288   C  CB  . ASN A 1 50  ? 98.792  162.511 109.044 1.00 121.61 ? 43  ASN A CB  1 
ATOM   289   C  CG  . ASN A 1 50  ? 97.628  162.377 110.000 1.00 121.61 ? 43  ASN A CG  1 
ATOM   290   O  OD1 . ASN A 1 50  ? 97.638  161.534 110.891 1.00 121.61 ? 43  ASN A OD1 1 
ATOM   291   N  ND2 . ASN A 1 50  ? 96.614  163.214 109.818 1.00 121.61 ? 43  ASN A ND2 1 
ATOM   292   N  N   . ALA A 1 51  ? 101.724 163.331 110.577 1.00 110.39 ? 44  ALA A N   1 
ATOM   293   C  CA  . ALA A 1 51  ? 102.446 163.972 111.663 1.00 110.39 ? 44  ALA A CA  1 
ATOM   294   C  C   . ALA A 1 51  ? 102.686 165.445 111.360 1.00 110.39 ? 44  ALA A C   1 
ATOM   295   O  O   . ALA A 1 51  ? 102.574 165.897 110.217 1.00 110.39 ? 44  ALA A O   1 
ATOM   296   C  CB  . ALA A 1 51  ? 103.785 163.273 111.924 1.00 110.39 ? 44  ALA A CB  1 
ATOM   297   N  N   . SER A 1 52  ? 103.019 166.189 112.412 1.00 106.07 ? 45  SER A N   1 
ATOM   298   C  CA  . SER A 1 52  ? 103.341 167.597 112.270 1.00 106.07 ? 45  SER A CA  1 
ATOM   299   C  C   . SER A 1 52  ? 104.682 167.765 111.555 1.00 106.07 ? 45  SER A C   1 
ATOM   300   O  O   . SER A 1 52  ? 105.536 166.875 111.604 1.00 106.07 ? 45  SER A O   1 
ATOM   301   C  CB  . SER A 1 52  ? 103.389 168.269 113.641 1.00 106.07 ? 45  SER A CB  1 
ATOM   302   O  OG  . SER A 1 52  ? 103.747 169.637 113.537 1.00 106.07 ? 45  SER A OG  1 
ATOM   303   N  N   . PRO A 1 53  ? 104.889 168.897 110.876 1.00 104.89 ? 46  PRO A N   1 
ATOM   304   C  CA  . PRO A 1 53  ? 106.165 169.098 110.167 1.00 104.89 ? 46  PRO A CA  1 
ATOM   305   C  C   . PRO A 1 53  ? 107.376 169.124 111.082 1.00 104.89 ? 46  PRO A C   1 
ATOM   306   O  O   . PRO A 1 53  ? 108.501 168.919 110.609 1.00 104.89 ? 46  PRO A O   1 
ATOM   307   C  CB  . PRO A 1 53  ? 105.963 170.448 109.464 1.00 104.89 ? 46  PRO A CB  1 
ATOM   308   C  CG  . PRO A 1 53  ? 104.484 170.605 109.357 1.00 104.89 ? 46  PRO A CG  1 
ATOM   309   C  CD  . PRO A 1 53  ? 103.927 169.975 110.595 1.00 104.89 ? 46  PRO A CD  1 
ATOM   310   N  N   . GLY A 1 54  ? 107.186 169.375 112.379 1.00 100.48 ? 47  GLY A N   1 
ATOM   311   C  CA  . GLY A 1 54  ? 108.321 169.451 113.282 1.00 100.48 ? 47  GLY A CA  1 
ATOM   312   C  C   . GLY A 1 54  ? 109.022 168.123 113.488 1.00 100.48 ? 47  GLY A C   1 
ATOM   313   O  O   . GLY A 1 54  ? 110.192 168.089 113.878 1.00 100.48 ? 47  GLY A O   1 
ATOM   314   N  N   . VAL A 1 55  ? 108.331 167.018 113.226 1.00 102.53 ? 48  VAL A N   1 
ATOM   315   C  CA  . VAL A 1 55  ? 108.875 165.687 113.448 1.00 102.53 ? 48  VAL A CA  1 
ATOM   316   C  C   . VAL A 1 55  ? 108.965 164.955 112.114 1.00 102.53 ? 48  VAL A C   1 
ATOM   317   O  O   . VAL A 1 55  ? 108.297 165.302 111.135 1.00 102.53 ? 48  VAL A O   1 
ATOM   318   C  CB  . VAL A 1 55  ? 108.030 164.890 114.464 1.00 102.53 ? 48  VAL A CB  1 
ATOM   319   C  CG1 . VAL A 1 55  ? 106.849 164.227 113.776 1.00 102.53 ? 48  VAL A CG1 1 
ATOM   320   C  CG2 . VAL A 1 55  ? 108.883 163.865 115.184 1.00 102.53 ? 48  VAL A CG2 1 
ATOM   321   N  N   . VAL A 1 56  ? 109.812 163.929 112.079 1.00 105.69 ? 49  VAL A N   1 
ATOM   322   C  CA  . VAL A 1 56  ? 110.029 163.112 110.891 1.00 105.69 ? 49  VAL A CA  1 
ATOM   323   C  C   . VAL A 1 56  ? 109.638 161.679 111.219 1.00 105.69 ? 49  VAL A C   1 
ATOM   324   O  O   . VAL A 1 56  ? 110.124 161.105 112.202 1.00 105.69 ? 49  VAL A O   1 
ATOM   325   C  CB  . VAL A 1 56  ? 111.490 163.186 110.416 1.00 105.69 ? 49  VAL A CB  1 
ATOM   326   C  CG1 . VAL A 1 56  ? 111.704 162.276 109.219 1.00 105.69 ? 49  VAL A CG1 1 
ATOM   327   C  CG2 . VAL A 1 56  ? 111.865 164.619 110.078 1.00 105.69 ? 49  VAL A CG2 1 
ATOM   328   N  N   . VAL A 1 57  ? 108.767 161.104 110.395 1.00 110.78 ? 50  VAL A N   1 
ATOM   329   C  CA  . VAL A 1 57  ? 108.279 159.742 110.571 1.00 110.78 ? 50  VAL A CA  1 
ATOM   330   C  C   . VAL A 1 57  ? 108.753 158.898 109.397 1.00 110.78 ? 50  VAL A C   1 
ATOM   331   O  O   . VAL A 1 57  ? 108.611 159.295 108.234 1.00 110.78 ? 50  VAL A O   1 
ATOM   332   C  CB  . VAL A 1 57  ? 106.742 159.708 110.702 1.00 110.78 ? 50  VAL A CB  1 
ATOM   333   C  CG1 . VAL A 1 57  ? 106.088 160.501 109.581 1.00 110.78 ? 50  VAL A CG1 1 
ATOM   334   C  CG2 . VAL A 1 57  ? 106.239 158.275 110.706 1.00 110.78 ? 50  VAL A CG2 1 
ATOM   335   N  N   . ASP A 1 58  ? 109.334 157.740 109.702 1.00 120.53 ? 51  ASP A N   1 
ATOM   336   C  CA  . ASP A 1 58  ? 109.865 156.841 108.684 1.00 120.53 ? 51  ASP A CA  1 
ATOM   337   C  C   . ASP A 1 58  ? 109.272 155.455 108.877 1.00 120.53 ? 51  ASP A C   1 
ATOM   338   O  O   . ASP A 1 58  ? 109.369 154.881 109.967 1.00 120.53 ? 51  ASP A O   1 
ATOM   339   C  CB  . ASP A 1 58  ? 111.395 156.784 108.745 1.00 120.53 ? 51  ASP A CB  1 
ATOM   340   C  CG  . ASP A 1 58  ? 111.963 155.599 107.992 1.00 120.53 ? 51  ASP A CG  1 
ATOM   341   O  OD1 . ASP A 1 58  ? 111.723 155.498 106.770 1.00 120.53 ? 51  ASP A OD1 1 
ATOM   342   O  OD2 . ASP A 1 58  ? 112.650 154.767 108.621 1.00 120.53 ? 51  ASP A OD2 1 
ATOM   343   N  N   . ILE A 1 59  ? 108.662 154.921 107.822 1.00 127.15 ? 52  ILE A N   1 
ATOM   344   C  CA  . ILE A 1 59  ? 108.145 153.557 107.818 1.00 127.15 ? 52  ILE A CA  1 
ATOM   345   C  C   . ILE A 1 59  ? 109.239 152.675 107.230 1.00 127.15 ? 52  ILE A C   1 
ATOM   346   O  O   . ILE A 1 59  ? 109.534 152.759 106.036 1.00 127.15 ? 52  ILE A O   1 
ATOM   347   C  CB  . ILE A 1 59  ? 106.850 153.444 107.004 1.00 127.15 ? 52  ILE A CB  1 
ATOM   348   C  CG1 . ILE A 1 59  ? 105.807 154.476 107.450 1.00 127.15 ? 52  ILE A CG1 1 
ATOM   349   C  CG2 . ILE A 1 59  ? 106.278 152.040 107.114 1.00 127.15 ? 52  ILE A CG2 1 
ATOM   350   C  CD1 . ILE A 1 59  ? 105.702 154.671 108.941 1.00 127.15 ? 52  ILE A CD1 1 
ATOM   351   N  N   . ALA A 1 60  ? 109.844 151.822 108.056 1.00 130.75 ? 53  ALA A N   1 
ATOM   352   C  CA  . ALA A 1 60  ? 111.036 151.080 107.643 1.00 130.75 ? 53  ALA A CA  1 
ATOM   353   C  C   . ALA A 1 60  ? 110.686 149.606 107.469 1.00 130.75 ? 53  ALA A C   1 
ATOM   354   O  O   . ALA A 1 60  ? 110.913 148.797 108.371 1.00 130.75 ? 53  ALA A O   1 
ATOM   355   C  CB  . ALA A 1 60  ? 112.166 151.275 108.660 1.00 130.75 ? 53  ALA A CB  1 
ATOM   356   N  N   . SER A 1 73  ? 101.157 154.891 101.147 1.00 141.44 ? 66  SER A N   1 
ATOM   357   C  CA  . SER A 1 73  ? 100.213 155.511 102.069 1.00 141.44 ? 66  SER A CA  1 
ATOM   358   C  C   . SER A 1 73  ? 99.755  154.517 103.130 1.00 141.44 ? 66  SER A C   1 
ATOM   359   O  O   . SER A 1 73  ? 100.213 154.557 104.271 1.00 141.44 ? 66  SER A O   1 
ATOM   360   C  CB  . SER A 1 73  ? 99.007  156.066 101.310 1.00 141.44 ? 66  SER A CB  1 
ATOM   361   O  OG  . SER A 1 73  ? 98.335  155.039 100.601 1.00 141.44 ? 66  SER A OG  1 
ATOM   362   N  N   . THR A 1 74  ? 98.843  153.628 102.747 1.00 143.44 ? 67  THR A N   1 
ATOM   363   C  CA  . THR A 1 74  ? 98.344  152.613 103.662 1.00 143.44 ? 67  THR A CA  1 
ATOM   364   C  C   . THR A 1 74  ? 99.317  151.445 103.741 1.00 143.44 ? 67  THR A C   1 
ATOM   365   O  O   . THR A 1 74  ? 99.866  151.003 102.728 1.00 143.44 ? 67  THR A O   1 
ATOM   366   C  CB  . THR A 1 74  ? 96.969  152.117 103.214 1.00 143.44 ? 67  THR A CB  1 
ATOM   367   O  OG1 . THR A 1 74  ? 97.055  151.603 101.879 1.00 143.44 ? 67  THR A OG1 1 
ATOM   368   C  CG2 . THR A 1 74  ? 95.956  153.252 103.251 1.00 143.44 ? 67  THR A CG2 1 
ATOM   369   N  N   . TRP A 1 75  ? 99.531  150.948 104.955 1.00 141.91 ? 68  TRP A N   1 
ATOM   370   C  CA  . TRP A 1 75  ? 100.441 149.842 105.198 1.00 141.91 ? 68  TRP A CA  1 
ATOM   371   C  C   . TRP A 1 75  ? 99.764  148.791 106.063 1.00 141.91 ? 68  TRP A C   1 
ATOM   372   O  O   . TRP A 1 75  ? 98.910  149.119 106.893 1.00 141.91 ? 68  TRP A O   1 
ATOM   373   C  CB  . TRP A 1 75  ? 101.726 150.321 105.891 1.00 141.91 ? 68  TRP A CB  1 
ATOM   374   C  CG  . TRP A 1 75  ? 102.610 151.171 105.028 1.00 141.91 ? 68  TRP A CG  1 
ATOM   375   C  CD1 . TRP A 1 75  ? 102.313 152.394 104.502 1.00 141.91 ? 68  TRP A CD1 1 
ATOM   376   C  CD2 . TRP A 1 75  ? 103.940 150.862 104.595 1.00 141.91 ? 68  TRP A CD2 1 
ATOM   377   N  NE1 . TRP A 1 75  ? 103.374 152.865 103.768 1.00 141.91 ? 68  TRP A NE1 1 
ATOM   378   C  CE2 . TRP A 1 75  ? 104.386 151.942 103.809 1.00 141.91 ? 68  TRP A CE2 1 
ATOM   379   C  CE3 . TRP A 1 75  ? 104.796 149.775 104.795 1.00 141.91 ? 68  TRP A CE3 1 
ATOM   380   C  CZ2 . TRP A 1 75  ? 105.649 151.968 103.223 1.00 141.91 ? 68  TRP A CZ2 1 
ATOM   381   C  CZ3 . TRP A 1 75  ? 106.051 149.803 104.212 1.00 141.91 ? 68  TRP A CZ3 1 
ATOM   382   C  CH2 . TRP A 1 75  ? 106.465 150.891 103.436 1.00 141.91 ? 68  TRP A CH2 1 
ATOM   383   N  N   . PRO A 1 76  ? 100.120 147.521 105.888 1.00 142.45 ? 69  PRO A N   1 
ATOM   384   C  CA  . PRO A 1 76  ? 99.578  146.480 106.767 1.00 142.45 ? 69  PRO A CA  1 
ATOM   385   C  C   . PRO A 1 76  ? 100.129 146.605 108.177 1.00 142.45 ? 69  PRO A C   1 
ATOM   386   O  O   . PRO A 1 76  ? 101.236 147.102 108.397 1.00 142.45 ? 69  PRO A O   1 
ATOM   387   C  CB  . PRO A 1 76  ? 100.038 145.179 106.102 1.00 142.45 ? 69  PRO A CB  1 
ATOM   388   C  CG  . PRO A 1 76  ? 101.267 145.560 105.352 1.00 142.45 ? 69  PRO A CG  1 
ATOM   389   C  CD  . PRO A 1 76  ? 101.046 146.971 104.882 1.00 142.45 ? 69  PRO A CD  1 
ATOM   390   N  N   . LEU A 1 77  ? 99.340  146.131 109.143 1.00 141.91 ? 70  LEU A N   1 
ATOM   391   C  CA  . LEU A 1 77  ? 99.695  146.208 110.555 1.00 141.91 ? 70  LEU A CA  1 
ATOM   392   C  C   . LEU A 1 77  ? 100.481 144.992 111.034 1.00 141.91 ? 70  LEU A C   1 
ATOM   393   O  O   . LEU A 1 77  ? 100.464 144.678 112.232 1.00 141.91 ? 70  LEU A O   1 
ATOM   394   C  CB  . LEU A 1 77  ? 98.434  146.416 111.398 1.00 141.91 ? 70  LEU A CB  1 
ATOM   395   C  CG  . LEU A 1 77  ? 97.310  145.374 111.365 1.00 141.91 ? 70  LEU A CG  1 
ATOM   396   C  CD1 . LEU A 1 77  ? 97.424  144.340 112.478 1.00 141.91 ? 70  LEU A CD1 1 
ATOM   397   C  CD2 . LEU A 1 77  ? 95.966  146.076 111.433 1.00 141.91 ? 70  LEU A CD2 1 
ATOM   398   N  N   . ASP A 1 78  ? 101.192 144.318 110.133 1.00 141.55 ? 71  ASP A N   1 
ATOM   399   C  CA  . ASP A 1 78  ? 101.962 143.145 110.512 1.00 141.55 ? 71  ASP A CA  1 
ATOM   400   C  C   . ASP A 1 78  ? 103.050 143.525 111.515 1.00 141.55 ? 71  ASP A C   1 
ATOM   401   O  O   . ASP A 1 78  ? 103.589 144.635 111.469 1.00 141.55 ? 71  ASP A O   1 
ATOM   402   C  CB  . ASP A 1 78  ? 102.591 142.503 109.278 1.00 141.55 ? 71  ASP A CB  1 
ATOM   403   C  CG  . ASP A 1 78  ? 103.547 143.435 108.563 1.00 141.55 ? 71  ASP A CG  1 
ATOM   404   O  OD1 . ASP A 1 78  ? 103.100 144.506 108.102 1.00 141.55 ? 71  ASP A OD1 1 
ATOM   405   O  OD2 . ASP A 1 78  ? 104.746 143.099 108.466 1.00 141.55 ? 71  ASP A OD2 1 
ATOM   406   N  N   . PRO A 1 79  ? 103.384 142.625 112.442 1.00 139.32 ? 72  PRO A N   1 
ATOM   407   C  CA  . PRO A 1 79  ? 104.399 142.956 113.457 1.00 139.32 ? 72  PRO A CA  1 
ATOM   408   C  C   . PRO A 1 79  ? 105.775 143.239 112.880 1.00 139.32 ? 72  PRO A C   1 
ATOM   409   O  O   . PRO A 1 79  ? 106.590 143.879 113.556 1.00 139.32 ? 72  PRO A O   1 
ATOM   410   C  CB  . PRO A 1 79  ? 104.418 141.710 114.354 1.00 139.32 ? 72  PRO A CB  1 
ATOM   411   C  CG  . PRO A 1 79  ? 103.098 141.048 114.120 1.00 139.32 ? 72  PRO A CG  1 
ATOM   412   C  CD  . PRO A 1 79  ? 102.775 141.306 112.681 1.00 139.32 ? 72  PRO A CD  1 
ATOM   413   N  N   . GLY A 1 80  ? 106.064 142.777 111.662 1.00 137.22 ? 73  GLY A N   1 
ATOM   414   C  CA  . GLY A 1 80  ? 107.385 142.994 111.096 1.00 137.22 ? 73  GLY A CA  1 
ATOM   415   C  C   . GLY A 1 80  ? 107.699 144.458 110.854 1.00 137.22 ? 73  GLY A C   1 
ATOM   416   O  O   . GLY A 1 80  ? 108.785 144.932 111.200 1.00 137.22 ? 73  GLY A O   1 
ATOM   417   N  N   . VAL A 1 81  ? 106.753 145.197 110.270 1.00 134.02 ? 74  VAL A N   1 
ATOM   418   C  CA  . VAL A 1 81  ? 106.995 146.592 109.918 1.00 134.02 ? 74  VAL A CA  1 
ATOM   419   C  C   . VAL A 1 81  ? 107.213 147.419 111.181 1.00 134.02 ? 74  VAL A C   1 
ATOM   420   O  O   . VAL A 1 81  ? 106.677 147.116 112.256 1.00 134.02 ? 74  VAL A O   1 
ATOM   421   C  CB  . VAL A 1 81  ? 105.827 147.143 109.076 1.00 134.02 ? 74  VAL A CB  1 
ATOM   422   C  CG1 . VAL A 1 81  ? 106.007 148.629 108.806 1.00 134.02 ? 74  VAL A CG1 1 
ATOM   423   C  CG2 . VAL A 1 81  ? 105.684 146.369 107.772 1.00 134.02 ? 74  VAL A CG2 1 
ATOM   424   N  N   . GLU A 1 82  ? 108.027 148.467 111.059 1.00 124.26 ? 75  GLU A N   1 
ATOM   425   C  CA  . GLU A 1 82  ? 108.341 149.330 112.187 1.00 124.26 ? 75  GLU A CA  1 
ATOM   426   C  C   . GLU A 1 82  ? 108.323 150.787 111.746 1.00 124.26 ? 75  GLU A C   1 
ATOM   427   O  O   . GLU A 1 82  ? 108.490 151.110 110.565 1.00 124.26 ? 75  GLU A O   1 
ATOM   428   C  CB  . GLU A 1 82  ? 109.698 148.973 112.810 1.00 124.26 ? 75  GLU A CB  1 
ATOM   429   C  CG  . GLU A 1 82  ? 110.897 149.576 112.103 1.00 124.26 ? 75  GLU A CG  1 
ATOM   430   C  CD  . GLU A 1 82  ? 112.197 149.277 112.822 1.00 124.26 ? 75  GLU A CD  1 
ATOM   431   O  OE1 . GLU A 1 82  ? 112.148 148.942 114.025 1.00 124.26 ? 75  GLU A OE1 1 
ATOM   432   O  OE2 . GLU A 1 82  ? 113.267 149.376 112.186 1.00 124.26 ? 75  GLU A OE2 1 
ATOM   433   N  N   . VAL A 1 83  ? 108.104 151.665 112.722 1.00 114.89 ? 76  VAL A N   1 
ATOM   434   C  CA  . VAL A 1 83  ? 107.972 153.099 112.500 1.00 114.89 ? 76  VAL A CA  1 
ATOM   435   C  C   . VAL A 1 83  ? 108.953 153.818 113.414 1.00 114.89 ? 76  VAL A C   1 
ATOM   436   O  O   . VAL A 1 83  ? 108.972 153.570 114.625 1.00 114.89 ? 76  VAL A O   1 
ATOM   437   C  CB  . VAL A 1 83  ? 106.536 153.587 112.770 1.00 114.89 ? 76  VAL A CB  1 
ATOM   438   C  CG1 . VAL A 1 83  ? 106.409 155.064 112.451 1.00 114.89 ? 76  VAL A CG1 1 
ATOM   439   C  CG2 . VAL A 1 83  ? 105.532 152.765 111.978 1.00 114.89 ? 76  VAL A CG2 1 
ATOM   440   N  N   . THR A 1 84  ? 109.753 154.713 112.842 1.00 109.35 ? 77  THR A N   1 
ATOM   441   C  CA  . THR A 1 84  ? 110.741 155.478 113.588 1.00 109.35 ? 77  THR A CA  1 
ATOM   442   C  C   . THR A 1 84  ? 110.385 156.959 113.565 1.00 109.35 ? 77  THR A C   1 
ATOM   443   O  O   . THR A 1 84  ? 109.931 157.483 112.542 1.00 109.35 ? 77  THR A O   1 
ATOM   444   C  CB  . THR A 1 84  ? 112.145 155.276 113.015 1.00 109.35 ? 77  THR A CB  1 
ATOM   445   O  OG1 . THR A 1 84  ? 112.262 155.981 111.774 1.00 109.35 ? 77  THR A OG1 1 
ATOM   446   C  CG2 . THR A 1 84  ? 112.415 153.799 112.781 1.00 109.35 ? 77  THR A CG2 1 
ATOM   447   N  N   . LEU A 1 85  ? 110.599 157.628 114.696 1.00 97.15  ? 78  LEU A N   1 
ATOM   448   C  CA  . LEU A 1 85  ? 110.275 159.036 114.866 1.00 97.15  ? 78  LEU A CA  1 
ATOM   449   C  C   . LEU A 1 85  ? 111.538 159.790 115.253 1.00 97.15  ? 78  LEU A C   1 
ATOM   450   O  O   . LEU A 1 85  ? 112.280 159.348 116.136 1.00 97.15  ? 78  LEU A O   1 
ATOM   451   C  CB  . LEU A 1 85  ? 109.198 159.221 115.936 1.00 97.15  ? 78  LEU A CB  1 
ATOM   452   C  CG  . LEU A 1 85  ? 108.192 160.349 115.720 1.00 97.15  ? 78  LEU A CG  1 
ATOM   453   C  CD1 . LEU A 1 85  ? 107.611 160.281 114.321 1.00 97.15  ? 78  LEU A CD1 1 
ATOM   454   C  CD2 . LEU A 1 85  ? 107.092 160.289 116.763 1.00 97.15  ? 78  LEU A CD2 1 
ATOM   455   N  N   . THR A 1 86  ? 111.783 160.921 114.593 1.00 98.79  ? 79  THR A N   1 
ATOM   456   C  CA  . THR A 1 86  ? 112.975 161.722 114.841 1.00 98.79  ? 79  THR A CA  1 
ATOM   457   C  C   . THR A 1 86  ? 112.595 163.192 114.943 1.00 98.79  ? 79  THR A C   1 
ATOM   458   O  O   . THR A 1 86  ? 111.904 163.721 114.067 1.00 98.79  ? 79  THR A O   1 
ATOM   459   C  CB  . THR A 1 86  ? 114.016 161.519 113.734 1.00 98.79  ? 79  THR A CB  1 
ATOM   460   O  OG1 . THR A 1 86  ? 114.559 160.197 113.825 1.00 98.79  ? 79  THR A OG1 1 
ATOM   461   C  CG2 . THR A 1 86  ? 115.145 162.528 113.868 1.00 98.79  ? 79  THR A CG2 1 
ATOM   462   N  N   . MET A 1 87  ? 113.052 163.848 116.004 1.00 93.81  ? 80  MET A N   1 
ATOM   463   C  CA  . MET A 1 87  ? 112.799 165.265 116.214 1.00 93.81  ? 80  MET A CA  1 
ATOM   464   C  C   . MET A 1 87  ? 114.020 166.075 115.799 1.00 93.81  ? 80  MET A C   1 
ATOM   465   O  O   . MET A 1 87  ? 115.154 165.598 115.892 1.00 93.81  ? 80  MET A O   1 
ATOM   466   C  CB  . MET A 1 87  ? 112.448 165.546 117.674 1.00 93.81  ? 80  MET A CB  1 
ATOM   467   C  CG  . MET A 1 87  ? 111.027 165.164 118.032 1.00 93.81  ? 80  MET A CG  1 
ATOM   468   S  SD  . MET A 1 87  ? 109.839 166.412 117.512 1.00 93.81  ? 80  MET A SD  1 
ATOM   469   C  CE  . MET A 1 87  ? 109.473 167.190 119.075 1.00 93.81  ? 80  MET A CE  1 
ATOM   470   N  N   . LYS A 1 88  ? 113.781 167.302 115.338 1.00 89.67  ? 81  LYS A N   1 
ATOM   471   C  CA  . LYS A 1 88  ? 114.850 168.147 114.818 1.00 89.67  ? 81  LYS A CA  1 
ATOM   472   C  C   . LYS A 1 88  ? 115.253 169.275 115.757 1.00 89.67  ? 81  LYS A C   1 
ATOM   473   O  O   . LYS A 1 88  ? 116.438 169.618 115.814 1.00 89.67  ? 81  LYS A O   1 
ATOM   474   C  CB  . LYS A 1 88  ? 114.442 168.745 113.468 1.00 89.67  ? 81  LYS A CB  1 
ATOM   475   C  CG  . LYS A 1 88  ? 113.615 167.813 112.600 1.00 89.67  ? 81  LYS A CG  1 
ATOM   476   C  CD  . LYS A 1 88  ? 113.439 168.375 111.198 1.00 89.67  ? 81  LYS A CD  1 
ATOM   477   C  CE  . LYS A 1 88  ? 112.559 169.614 111.201 1.00 89.67  ? 81  LYS A CE  1 
ATOM   478   N  NZ  . LYS A 1 88  ? 111.144 169.288 111.522 1.00 89.67  ? 81  LYS A NZ  1 
ATOM   479   N  N   . ALA A 1 89  ? 114.311 169.859 116.493 1.00 82.29  ? 82  ALA A N   1 
ATOM   480   C  CA  . ALA A 1 89  ? 114.603 171.006 117.340 1.00 82.29  ? 82  ALA A CA  1 
ATOM   481   C  C   . ALA A 1 89  ? 114.001 170.793 118.721 1.00 82.29  ? 82  ALA A C   1 
ATOM   482   O  O   . ALA A 1 89  ? 113.027 170.058 118.892 1.00 82.29  ? 82  ALA A O   1 
ATOM   483   C  CB  . ALA A 1 89  ? 114.074 172.309 116.729 1.00 82.29  ? 82  ALA A CB  1 
ATOM   484   N  N   . ALA A 1 90  ? 114.599 171.454 119.709 1.00 77.48  ? 83  ALA A N   1 
ATOM   485   C  CA  . ALA A 1 90  ? 114.117 171.359 121.078 1.00 77.48  ? 83  ALA A CA  1 
ATOM   486   C  C   . ALA A 1 90  ? 112.746 172.009 121.214 1.00 77.48  ? 83  ALA A C   1 
ATOM   487   O  O   . ALA A 1 90  ? 112.388 172.924 120.469 1.00 77.48  ? 83  ALA A O   1 
ATOM   488   C  CB  . ALA A 1 90  ? 115.104 172.018 122.040 1.00 77.48  ? 83  ALA A CB  1 
ATOM   489   N  N   . SER A 1 91  ? 111.975 171.522 122.181 1.00 78.77  ? 84  SER A N   1 
ATOM   490   C  CA  . SER A 1 91  ? 110.624 172.018 122.396 1.00 78.77  ? 84  SER A CA  1 
ATOM   491   C  C   . SER A 1 91  ? 110.639 173.314 123.193 1.00 78.77  ? 84  SER A C   1 
ATOM   492   O  O   . SER A 1 91  ? 111.384 173.455 124.166 1.00 78.77  ? 84  SER A O   1 
ATOM   493   C  CB  . SER A 1 91  ? 109.785 170.971 123.125 1.00 78.77  ? 84  SER A CB  1 
ATOM   494   O  OG  . SER A 1 91  ? 109.778 169.744 122.420 1.00 78.77  ? 84  SER A OG  1 
ATOM   495   N  N   . GLY A 1 92  ? 109.809 174.264 122.770 1.00 81.78  ? 85  GLY A N   1 
ATOM   496   C  CA  . GLY A 1 92  ? 109.648 175.505 123.499 1.00 81.78  ? 85  GLY A CA  1 
ATOM   497   C  C   . GLY A 1 92  ? 108.521 175.443 124.508 1.00 81.78  ? 85  GLY A C   1 
ATOM   498   O  O   . GLY A 1 92  ? 108.433 176.284 125.407 1.00 81.78  ? 85  GLY A O   1 
ATOM   499   N  N   . SER A 1 93  ? 107.650 174.445 124.369 1.00 83.17  ? 86  SER A N   1 
ATOM   500   C  CA  . SER A 1 93  ? 106.527 174.273 125.277 1.00 83.17  ? 86  SER A CA  1 
ATOM   501   C  C   . SER A 1 93  ? 106.143 172.802 125.315 1.00 83.17  ? 86  SER A C   1 
ATOM   502   O  O   . SER A 1 93  ? 106.480 172.028 124.415 1.00 83.17  ? 86  SER A O   1 
ATOM   503   C  CB  . SER A 1 93  ? 105.327 175.132 124.861 1.00 83.17  ? 86  SER A CB  1 
ATOM   504   O  OG  . SER A 1 93  ? 104.833 174.737 123.594 1.00 83.17  ? 86  SER A OG  1 
ATOM   505   N  N   . THR A 1 94  ? 105.428 172.425 126.371 1.00 86.51  ? 87  THR A N   1 
ATOM   506   C  CA  . THR A 1 94  ? 105.044 171.034 126.555 1.00 86.51  ? 87  THR A CA  1 
ATOM   507   C  C   . THR A 1 94  ? 103.980 170.622 125.542 1.00 86.51  ? 87  THR A C   1 
ATOM   508   O  O   . THR A 1 94  ? 103.022 171.353 125.278 1.00 86.51  ? 87  THR A O   1 
ATOM   509   C  CB  . THR A 1 94  ? 104.522 170.808 127.974 1.00 86.51  ? 87  THR A CB  1 
ATOM   510   O  OG1 . THR A 1 94  ? 105.402 171.437 128.914 1.00 86.51  ? 87  THR A OG1 1 
ATOM   511   C  CG2 . THR A 1 94  ? 104.445 169.321 128.283 1.00 86.51  ? 87  THR A CG2 1 
ATOM   512   N  N   . GLY A 1 95  ? 104.160 169.430 124.975 1.00 90.99  ? 88  GLY A N   1 
ATOM   513   C  CA  . GLY A 1 95  ? 103.195 168.859 124.057 1.00 90.99  ? 88  GLY A CA  1 
ATOM   514   C  C   . GLY A 1 95  ? 102.971 169.679 122.805 1.00 90.99  ? 88  GLY A C   1 
ATOM   515   O  O   . GLY A 1 95  ? 101.825 169.917 122.414 1.00 90.99  ? 88  GLY A O   1 
ATOM   516   N  N   . ASP A 1 96  ? 104.051 170.125 122.168 1.00 90.41  ? 89  ASP A N   1 
ATOM   517   C  CA  . ASP A 1 96  ? 103.919 170.990 121.006 1.00 90.41  ? 89  ASP A CA  1 
ATOM   518   C  C   . ASP A 1 96  ? 103.945 170.243 119.677 1.00 90.41  ? 89  ASP A C   1 
ATOM   519   O  O   . ASP A 1 96  ? 103.808 170.885 118.631 1.00 90.41  ? 89  ASP A O   1 
ATOM   520   C  CB  . ASP A 1 96  ? 105.000 172.085 121.037 1.00 90.41  ? 89  ASP A CB  1 
ATOM   521   C  CG  . ASP A 1 96  ? 106.385 171.579 120.663 1.00 90.41  ? 89  ASP A CG  1 
ATOM   522   O  OD1 . ASP A 1 96  ? 106.583 171.054 119.550 1.00 90.41  ? 89  ASP A OD1 1 
ATOM   523   O  OD2 . ASP A 1 96  ? 107.294 171.722 121.502 1.00 90.41  ? 89  ASP A OD2 1 
ATOM   524   N  N   . GLN A 1 97  ? 104.117 168.921 119.674 1.00 94.76  ? 90  GLN A N   1 
ATOM   525   C  CA  . GLN A 1 97  ? 103.969 168.163 118.438 1.00 94.76  ? 90  GLN A CA  1 
ATOM   526   C  C   . GLN A 1 97  ? 102.867 167.126 118.585 1.00 94.76  ? 90  GLN A C   1 
ATOM   527   O  O   . GLN A 1 97  ? 102.652 166.579 119.665 1.00 94.76  ? 90  GLN A O   1 
ATOM   528   C  CB  . GLN A 1 97  ? 105.276 167.480 118.021 1.00 94.76  ? 90  GLN A CB  1 
ATOM   529   C  CG  . GLN A 1 97  ? 106.485 168.403 117.932 1.00 94.76  ? 90  GLN A CG  1 
ATOM   530   C  CD  . GLN A 1 97  ? 106.388 169.480 116.854 1.00 94.76  ? 90  GLN A CD  1 
ATOM   531   O  OE1 . GLN A 1 97  ? 105.313 169.789 116.341 1.00 94.76  ? 90  GLN A OE1 1 
ATOM   532   N  NE2 . GLN A 1 97  ? 107.533 170.057 116.509 1.00 94.76  ? 90  GLN A NE2 1 
ATOM   533   N  N   . LYS A 1 98  ? 102.171 166.861 117.482 1.00 99.19  ? 91  LYS A N   1 
ATOM   534   C  CA  . LYS A 1 98  ? 101.092 165.885 117.473 1.00 99.19  ? 91  LYS A CA  1 
ATOM   535   C  C   . LYS A 1 98  ? 101.262 164.944 116.292 1.00 99.19  ? 91  LYS A C   1 
ATOM   536   O  O   . LYS A 1 98  ? 101.583 165.376 115.182 1.00 99.19  ? 91  LYS A O   1 
ATOM   537   C  CB  . LYS A 1 98  ? 99.719  166.567 117.409 1.00 99.19  ? 91  LYS A CB  1 
ATOM   538   C  CG  . LYS A 1 98  ? 99.603  167.641 116.342 1.00 99.19  ? 91  LYS A CG  1 
ATOM   539   C  CD  . LYS A 1 98  ? 98.219  168.267 116.342 1.00 99.19  ? 91  LYS A CD  1 
ATOM   540   C  CE  . LYS A 1 98  ? 97.145  167.227 116.071 1.00 99.19  ? 91  LYS A CE  1 
ATOM   541   N  NZ  . LYS A 1 98  ? 97.354  166.540 114.767 1.00 99.19  ? 91  LYS A NZ  1 
ATOM   542   N  N   . VAL A 1 99  ? 101.053 163.654 116.544 1.00 106.89 ? 92  VAL A N   1 
ATOM   543   C  CA  . VAL A 1 99  ? 101.080 162.623 115.514 1.00 106.89 ? 92  VAL A CA  1 
ATOM   544   C  C   . VAL A 1 99  ? 99.777  161.844 115.605 1.00 106.89 ? 92  VAL A C   1 
ATOM   545   O  O   . VAL A 1 99  ? 99.362  161.451 116.702 1.00 106.89 ? 92  VAL A O   1 
ATOM   546   C  CB  . VAL A 1 99  ? 102.288 161.680 115.674 1.00 106.89 ? 92  VAL A CB  1 
ATOM   547   C  CG1 . VAL A 1 99  ? 102.241 160.573 114.636 1.00 106.89 ? 92  VAL A CG1 1 
ATOM   548   C  CG2 . VAL A 1 99  ? 103.587 162.459 115.564 1.00 106.89 ? 92  VAL A CG2 1 
ATOM   549   N  N   . GLN A 1 100 ? 99.127  161.629 114.463 1.00 121.88 ? 93  GLN A N   1 
ATOM   550   C  CA  . GLN A 1 100 ? 97.854  160.930 114.412 1.00 121.88 ? 93  GLN A CA  1 
ATOM   551   C  C   . GLN A 1 100 ? 97.993  159.675 113.563 1.00 121.88 ? 93  GLN A C   1 
ATOM   552   O  O   . GLN A 1 100 ? 98.666  159.678 112.523 1.00 121.88 ? 93  GLN A O   1 
ATOM   553   C  CB  . GLN A 1 100 ? 96.748  161.838 113.856 1.00 121.88 ? 93  GLN A CB  1 
ATOM   554   C  CG  . GLN A 1 100 ? 95.410  161.146 113.651 1.00 121.88 ? 93  GLN A CG  1 
ATOM   555   C  CD  . GLN A 1 100 ? 94.416  162.009 112.901 1.00 121.88 ? 93  GLN A CD  1 
ATOM   556   O  OE1 . GLN A 1 100 ? 93.879  161.605 111.869 1.00 121.88 ? 93  GLN A OE1 1 
ATOM   557   N  NE2 . GLN A 1 100 ? 94.163  163.206 113.418 1.00 121.88 ? 93  GLN A NE2 1 
ATOM   558   N  N   . ILE A 1 101 ? 97.373  158.596 114.033 1.00 127.43 ? 94  ILE A N   1 
ATOM   559   C  CA  . ILE A 1 101 ? 97.359  157.314 113.342 1.00 127.43 ? 94  ILE A CA  1 
ATOM   560   C  C   . ILE A 1 101 ? 95.910  156.947 113.060 1.00 127.43 ? 94  ILE A C   1 
ATOM   561   O  O   . ILE A 1 101 ? 95.087  156.894 113.981 1.00 127.43 ? 94  ILE A O   1 
ATOM   562   C  CB  . ILE A 1 101 ? 98.048  156.212 114.167 1.00 127.43 ? 94  ILE A CB  1 
ATOM   563   C  CG1 . ILE A 1 101 ? 99.428  156.674 114.638 1.00 127.43 ? 94  ILE A CG1 1 
ATOM   564   C  CG2 . ILE A 1 101 ? 98.152  154.930 113.358 1.00 127.43 ? 94  ILE A CG2 1 
ATOM   565   C  CD1 . ILE A 1 101 ? 99.477  157.046 116.102 1.00 127.43 ? 94  ILE A CD1 1 
ATOM   566   N  N   . SER A 1 102 ? 95.602  156.694 111.793 1.00 136.73 ? 95  SER A N   1 
ATOM   567   C  CA  . SER A 1 102 ? 94.264  156.304 111.365 1.00 136.73 ? 95  SER A CA  1 
ATOM   568   C  C   . SER A 1 102 ? 94.282  154.814 111.050 1.00 136.73 ? 95  SER A C   1 
ATOM   569   O  O   . SER A 1 102 ? 94.924  154.386 110.085 1.00 136.73 ? 95  SER A O   1 
ATOM   570   C  CB  . SER A 1 102 ? 93.817  157.118 110.153 1.00 136.73 ? 95  SER A CB  1 
ATOM   571   O  OG  . SER A 1 102 ? 94.600  156.807 109.014 1.00 136.73 ? 95  SER A OG  1 
ATOM   572   N  N   . TYR A 1 103 ? 93.592  154.030 111.872 1.00 137.66 ? 96  TYR A N   1 
ATOM   573   C  CA  . TYR A 1 103 ? 93.448  152.599 111.663 1.00 137.66 ? 96  TYR A CA  1 
ATOM   574   C  C   . TYR A 1 103 ? 92.242  152.337 110.772 1.00 137.66 ? 96  TYR A C   1 
ATOM   575   O  O   . TYR A 1 103 ? 91.131  152.797 111.067 1.00 137.66 ? 96  TYR A O   1 
ATOM   576   C  CB  . TYR A 1 103 ? 93.284  151.877 112.999 1.00 137.66 ? 96  TYR A CB  1 
ATOM   577   C  CG  . TYR A 1 103 ? 94.508  151.908 113.883 1.00 137.66 ? 96  TYR A CG  1 
ATOM   578   C  CD1 . TYR A 1 103 ? 95.692  151.303 113.486 1.00 137.66 ? 96  TYR A CD1 1 
ATOM   579   C  CD2 . TYR A 1 103 ? 94.474  152.534 115.121 1.00 137.66 ? 96  TYR A CD2 1 
ATOM   580   C  CE1 . TYR A 1 103 ? 96.810  151.326 114.296 1.00 137.66 ? 96  TYR A CE1 1 
ATOM   581   C  CE2 . TYR A 1 103 ? 95.585  152.562 115.936 1.00 137.66 ? 96  TYR A CE2 1 
ATOM   582   C  CZ  . TYR A 1 103 ? 96.751  151.957 115.520 1.00 137.66 ? 96  TYR A CZ  1 
ATOM   583   O  OH  . TYR A 1 103 ? 97.858  151.987 116.335 1.00 137.66 ? 96  TYR A OH  1 
ATOM   584   N  N   . TYR A 1 104 ? 92.465  151.590 109.692 1.00 144.78 ? 97  TYR A N   1 
ATOM   585   C  CA  . TYR A 1 104 ? 91.446  151.287 108.695 1.00 144.78 ? 97  TYR A CA  1 
ATOM   586   C  C   . TYR A 1 104 ? 91.050  149.823 108.820 1.00 144.78 ? 97  TYR A C   1 
ATOM   587   O  O   . TYR A 1 104 ? 91.907  148.936 108.736 1.00 144.78 ? 97  TYR A O   1 
ATOM   588   C  CB  . TYR A 1 104 ? 91.960  151.575 107.284 1.00 144.78 ? 97  TYR A CB  1 
ATOM   589   C  CG  . TYR A 1 104 ? 92.326  153.019 107.038 1.00 144.78 ? 97  TYR A CG  1 
ATOM   590   C  CD1 . TYR A 1 104 ? 91.405  154.035 107.247 1.00 144.78 ? 97  TYR A CD1 1 
ATOM   591   C  CD2 . TYR A 1 104 ? 93.594  153.366 106.591 1.00 144.78 ? 97  TYR A CD2 1 
ATOM   592   C  CE1 . TYR A 1 104 ? 91.736  155.357 107.021 1.00 144.78 ? 97  TYR A CE1 1 
ATOM   593   C  CE2 . TYR A 1 104 ? 93.935  154.684 106.362 1.00 144.78 ? 97  TYR A CE2 1 
ATOM   594   C  CZ  . TYR A 1 104 ? 93.002  155.676 106.579 1.00 144.78 ? 97  TYR A CZ  1 
ATOM   595   O  OH  . TYR A 1 104 ? 93.337  156.991 106.352 1.00 144.78 ? 97  TYR A OH  1 
ATOM   596   N  N   . GLY A 1 105 ? 89.758  149.572 109.006 1.00 154.15 ? 98  GLY A N   1 
ATOM   597   C  CA  . GLY A 1 105 ? 89.251  148.225 109.101 1.00 154.15 ? 98  GLY A CA  1 
ATOM   598   C  C   . GLY A 1 105 ? 88.135  147.964 108.112 1.00 154.15 ? 98  GLY A C   1 
ATOM   599   O  O   . GLY A 1 105 ? 87.435  148.882 107.674 1.00 154.15 ? 98  GLY A O   1 
ATOM   600   N  N   . PRO A 1 106 ? 87.957  146.697 107.727 1.00 158.00 ? 99  PRO A N   1 
ATOM   601   C  CA  . PRO A 1 106 ? 86.846  146.360 106.821 1.00 158.00 ? 99  PRO A CA  1 
ATOM   602   C  C   . PRO A 1 106 ? 85.484  146.713 107.389 1.00 158.00 ? 99  PRO A C   1 
ATOM   603   O  O   . PRO A 1 106 ? 84.576  147.069 106.628 1.00 158.00 ? 99  PRO A O   1 
ATOM   604   C  CB  . PRO A 1 106 ? 87.001  144.845 106.620 1.00 158.00 ? 99  PRO A CB  1 
ATOM   605   C  CG  . PRO A 1 106 ? 87.831  144.380 107.776 1.00 158.00 ? 99  PRO A CG  1 
ATOM   606   C  CD  . PRO A 1 106 ? 88.747  145.515 108.106 1.00 158.00 ? 99  PRO A CD  1 
ATOM   607   N  N   . LYS A 1 107 ? 85.317  146.625 108.704 1.00 160.42 ? 100 LYS A N   1 
ATOM   608   C  CA  . LYS A 1 107 ? 84.084  147.001 109.376 1.00 160.42 ? 100 LYS A CA  1 
ATOM   609   C  C   . LYS A 1 107 ? 84.343  148.190 110.293 1.00 160.42 ? 100 LYS A C   1 
ATOM   610   O  O   . LYS A 1 107 ? 85.464  148.392 110.769 1.00 160.42 ? 100 LYS A O   1 
ATOM   611   C  CB  . LYS A 1 107 ? 83.517  145.830 110.185 1.00 160.42 ? 100 LYS A CB  1 
ATOM   612   C  CG  . LYS A 1 107 ? 83.172  144.608 109.350 1.00 160.42 ? 100 LYS A CG  1 
ATOM   613   C  CD  . LYS A 1 107 ? 82.715  143.452 110.225 1.00 160.42 ? 100 LYS A CD  1 
ATOM   614   C  CE  . LYS A 1 107 ? 82.364  142.231 109.390 1.00 160.42 ? 100 LYS A CE  1 
ATOM   615   N  NZ  . LYS A 1 107 ? 81.932  141.084 110.236 1.00 160.42 ? 100 LYS A NZ  1 
ATOM   616   N  N   . THR A 1 108 ? 83.287  148.983 110.523 1.00 159.36 ? 101 THR A N   1 
ATOM   617   C  CA  . THR A 1 108 ? 83.278  150.172 111.376 1.00 159.36 ? 101 THR A CA  1 
ATOM   618   C  C   . THR A 1 108 ? 84.154  151.279 110.793 1.00 159.36 ? 101 THR A C   1 
ATOM   619   O  O   . THR A 1 108 ? 85.068  151.005 110.006 1.00 159.36 ? 101 THR A O   1 
ATOM   620   C  CB  . THR A 1 108 ? 83.725  149.831 112.805 1.00 159.36 ? 101 THR A CB  1 
ATOM   621   O  OG1 . THR A 1 108 ? 85.129  149.542 112.821 1.00 159.36 ? 101 THR A OG1 1 
ATOM   622   C  CG2 . THR A 1 108 ? 82.948  148.636 113.346 1.00 159.36 ? 101 THR A CG2 1 
ATOM   623   N  N   . PRO A 1 109 ? 83.897  152.539 111.140 1.00 157.22 ? 102 PRO A N   1 
ATOM   624   C  CA  . PRO A 1 109 ? 84.712  153.642 110.610 1.00 157.22 ? 102 PRO A CA  1 
ATOM   625   C  C   . PRO A 1 109 ? 86.134  153.580 111.136 1.00 157.22 ? 102 PRO A C   1 
ATOM   626   O  O   . PRO A 1 109 ? 86.399  152.937 112.164 1.00 157.22 ? 102 PRO A O   1 
ATOM   627   C  CB  . PRO A 1 109 ? 83.983  154.897 111.118 1.00 157.22 ? 102 PRO A CB  1 
ATOM   628   C  CG  . PRO A 1 109 ? 82.594  154.442 111.411 1.00 157.22 ? 102 PRO A CG  1 
ATOM   629   C  CD  . PRO A 1 109 ? 82.728  153.032 111.888 1.00 157.22 ? 102 PRO A CD  1 
ATOM   630   N  N   . PRO A 1 110 ? 87.081  154.224 110.450 1.00 148.90 ? 103 PRO A N   1 
ATOM   631   C  CA  . PRO A 1 110 ? 88.473  154.211 110.915 1.00 148.90 ? 103 PRO A CA  1 
ATOM   632   C  C   . PRO A 1 110 ? 88.611  154.843 112.292 1.00 148.90 ? 103 PRO A C   1 
ATOM   633   O  O   . PRO A 1 110 ? 87.862  155.749 112.663 1.00 148.90 ? 103 PRO A O   1 
ATOM   634   C  CB  . PRO A 1 110 ? 89.212  155.031 109.850 1.00 148.90 ? 103 PRO A CB  1 
ATOM   635   C  CG  . PRO A 1 110 ? 88.331  154.969 108.644 1.00 148.90 ? 103 PRO A CG  1 
ATOM   636   C  CD  . PRO A 1 110 ? 86.933  154.941 109.173 1.00 148.90 ? 103 PRO A CD  1 
ATOM   637   N  N   . VAL A 1 111 ? 89.587  154.353 113.054 1.00 137.95 ? 104 VAL A N   1 
ATOM   638   C  CA  . VAL A 1 111 ? 89.794  154.768 114.439 1.00 137.95 ? 104 VAL A CA  1 
ATOM   639   C  C   . VAL A 1 111 ? 91.050  155.625 114.510 1.00 137.95 ? 104 VAL A C   1 
ATOM   640   O  O   . VAL A 1 111 ? 92.091  155.258 113.957 1.00 137.95 ? 104 VAL A O   1 
ATOM   641   C  CB  . VAL A 1 111 ? 89.900  153.556 115.380 1.00 137.95 ? 104 VAL A CB  1 
ATOM   642   C  CG1 . VAL A 1 111 ? 89.887  154.010 116.831 1.00 137.95 ? 104 VAL A CG1 1 
ATOM   643   C  CG2 . VAL A 1 111 ? 88.767  152.578 115.112 1.00 137.95 ? 104 VAL A CG2 1 
ATOM   644   N  N   . LYS A 1 112 ? 90.958  156.759 115.197 1.00 131.05 ? 105 LYS A N   1 
ATOM   645   C  CA  . LYS A 1 112 ? 92.052  157.718 115.272 1.00 131.05 ? 105 LYS A CA  1 
ATOM   646   C  C   . LYS A 1 112 ? 92.738  157.628 116.628 1.00 131.05 ? 105 LYS A C   1 
ATOM   647   O  O   . LYS A 1 112 ? 92.073  157.640 117.669 1.00 131.05 ? 105 LYS A O   1 
ATOM   648   C  CB  . LYS A 1 112 ? 91.547  159.142 115.029 1.00 131.05 ? 105 LYS A CB  1 
ATOM   649   C  CG  . LYS A 1 112 ? 91.087  159.395 113.604 1.00 131.05 ? 105 LYS A CG  1 
ATOM   650   C  CD  . LYS A 1 112 ? 90.701  160.849 113.394 1.00 131.05 ? 105 LYS A CD  1 
ATOM   651   C  CE  . LYS A 1 112 ? 90.312  161.110 111.948 1.00 131.05 ? 105 LYS A CE  1 
ATOM   652   N  NZ  . LYS A 1 112 ? 90.013  162.548 111.703 1.00 131.05 ? 105 LYS A NZ  1 
ATOM   653   N  N   . ALA A 1 113 ? 94.066  157.537 116.608 1.00 119.83 ? 106 ALA A N   1 
ATOM   654   C  CA  . ALA A 1 113 ? 94.887  157.540 117.808 1.00 119.83 ? 106 ALA A CA  1 
ATOM   655   C  C   . ALA A 1 113 ? 95.845  158.722 117.759 1.00 119.83 ? 106 ALA A C   1 
ATOM   656   O  O   . ALA A 1 113 ? 96.333  159.100 116.690 1.00 119.83 ? 106 ALA A O   1 
ATOM   657   C  CB  . ALA A 1 113 ? 95.672  156.232 117.952 1.00 119.83 ? 106 ALA A CB  1 
ATOM   658   N  N   . LEU A 1 114 ? 96.121  159.298 118.928 1.00 106.05 ? 107 LEU A N   1 
ATOM   659   C  CA  . LEU A 1 114 ? 96.884  160.533 119.031 1.00 106.05 ? 107 LEU A CA  1 
ATOM   660   C  C   . LEU A 1 114 ? 98.112  160.326 119.905 1.00 106.05 ? 107 LEU A C   1 
ATOM   661   O  O   . LEU A 1 114 ? 98.101  159.524 120.843 1.00 106.05 ? 107 LEU A O   1 
ATOM   662   C  CB  . LEU A 1 114 ? 96.028  161.666 119.613 1.00 106.05 ? 107 LEU A CB  1 
ATOM   663   C  CG  . LEU A 1 114 ? 95.258  162.546 118.627 1.00 106.05 ? 107 LEU A CG  1 
ATOM   664   C  CD1 . LEU A 1 114 ? 94.991  163.912 119.234 1.00 106.05 ? 107 LEU A CD1 1 
ATOM   665   C  CD2 . LEU A 1 114 ? 96.016  162.679 117.317 1.00 106.05 ? 107 LEU A CD2 1 
ATOM   666   N  N   . LEU A 1 115 ? 99.176  161.063 119.588 1.00 97.30  ? 108 LEU A N   1 
ATOM   667   C  CA  . LEU A 1 115 ? 100.389 161.056 120.395 1.00 97.30  ? 108 LEU A CA  1 
ATOM   668   C  C   . LEU A 1 115 ? 100.974 162.459 120.431 1.00 97.30  ? 108 LEU A C   1 
ATOM   669   O  O   . LEU A 1 115 ? 101.195 163.066 119.380 1.00 97.30  ? 108 LEU A O   1 
ATOM   670   C  CB  . LEU A 1 115 ? 101.420 160.069 119.840 1.00 97.30  ? 108 LEU A CB  1 
ATOM   671   C  CG  . LEU A 1 115 ? 102.761 160.041 120.572 1.00 97.30  ? 108 LEU A CG  1 
ATOM   672   C  CD1 . LEU A 1 115 ? 102.587 159.506 121.983 1.00 97.30  ? 108 LEU A CD1 1 
ATOM   673   C  CD2 . LEU A 1 115 ? 103.777 159.216 119.804 1.00 97.30  ? 108 LEU A CD2 1 
ATOM   674   N  N   . TYR A 1 116 ? 101.227 162.967 121.635 1.00 94.63  ? 109 TYR A N   1 
ATOM   675   C  CA  . TYR A 1 116 ? 101.774 164.303 121.834 1.00 94.63  ? 109 TYR A CA  1 
ATOM   676   C  C   . TYR A 1 116 ? 103.243 164.206 122.220 1.00 94.63  ? 109 TYR A C   1 
ATOM   677   O  O   . TYR A 1 116 ? 103.609 163.418 123.098 1.00 94.63  ? 109 TYR A O   1 
ATOM   678   C  CB  . TYR A 1 116 ? 100.993 165.064 122.906 1.00 94.63  ? 109 TYR A CB  1 
ATOM   679   C  CG  . TYR A 1 116 ? 99.656  165.580 122.430 1.00 94.63  ? 109 TYR A CG  1 
ATOM   680   C  CD1 . TYR A 1 116 ? 99.551  166.302 121.250 1.00 94.63  ? 109 TYR A CD1 1 
ATOM   681   C  CD2 . TYR A 1 116 ? 98.500  165.354 123.164 1.00 94.63  ? 109 TYR A CD2 1 
ATOM   682   C  CE1 . TYR A 1 116 ? 98.334  166.779 120.809 1.00 94.63  ? 109 TYR A CE1 1 
ATOM   683   C  CE2 . TYR A 1 116 ? 97.277  165.828 122.732 1.00 94.63  ? 109 TYR A CE2 1 
ATOM   684   C  CZ  . TYR A 1 116 ? 97.200  166.540 121.554 1.00 94.63  ? 109 TYR A CZ  1 
ATOM   685   O  OH  . TYR A 1 116 ? 95.985  167.015 121.119 1.00 94.63  ? 109 TYR A OH  1 
ATOM   686   N  N   . LEU A 1 117 ? 104.074 165.012 121.569 1.00 92.96  ? 110 LEU A N   1 
ATOM   687   C  CA  . LEU A 1 117 ? 105.519 164.949 121.711 1.00 92.96  ? 110 LEU A CA  1 
ATOM   688   C  C   . LEU A 1 117 ? 106.075 166.278 122.199 1.00 92.96  ? 110 LEU A C   1 
ATOM   689   O  O   . LEU A 1 117 ? 105.736 167.347 121.666 1.00 92.96  ? 110 LEU A O   1 
ATOM   690   C  CB  . LEU A 1 117 ? 106.197 164.579 120.388 1.00 92.96  ? 110 LEU A CB  1 
ATOM   691   C  CG  . LEU A 1 117 ? 106.191 163.108 119.977 1.00 92.96  ? 110 LEU A CG  1 
ATOM   692   C  CD1 . LEU A 1 117 ? 106.508 162.220 121.168 1.00 92.96  ? 110 LEU A CD1 1 
ATOM   693   C  CD2 . LEU A 1 117 ? 104.867 162.724 119.346 1.00 92.96  ? 110 LEU A CD2 1 
ATOM   694   N  N   . THR A 1 118 ? 106.925 166.184 123.223 1.00 85.85  ? 111 THR A N   1 
ATOM   695   C  CA  . THR A 1 118 ? 107.789 167.260 123.697 1.00 85.85  ? 111 THR A CA  1 
ATOM   696   C  C   . THR A 1 118 ? 109.220 166.742 123.670 1.00 85.85  ? 111 THR A C   1 
ATOM   697   O  O   . THR A 1 118 ? 109.498 165.665 124.206 1.00 85.85  ? 111 THR A O   1 
ATOM   698   C  CB  . THR A 1 118 ? 107.412 167.693 125.115 1.00 85.85  ? 111 THR A CB  1 
ATOM   699   O  OG1 . THR A 1 118 ? 108.133 168.879 125.467 1.00 85.85  ? 111 THR A OG1 1 
ATOM   700   C  CG2 . THR A 1 118 ? 107.726 166.593 126.115 1.00 85.85  ? 111 THR A CG2 1 
ATOM   701   N  N   . ALA A 1 119 ? 110.122 167.499 123.055 1.00 76.64  ? 112 ALA A N   1 
ATOM   702   C  CA  . ALA A 1 119 ? 111.510 167.083 122.915 1.00 76.64  ? 112 ALA A CA  1 
ATOM   703   C  C   . ALA A 1 119 ? 112.424 167.983 123.730 1.00 76.64  ? 112 ALA A C   1 
ATOM   704   O  O   . ALA A 1 119 ? 112.300 169.210 123.695 1.00 76.64  ? 112 ALA A O   1 
ATOM   705   C  CB  . ALA A 1 119 ? 111.957 167.101 121.455 1.00 76.64  ? 112 ALA A CB  1 
ATOM   706   N  N   . VAL A 1 120 ? 113.353 167.362 124.448 1.00 65.09  ? 113 VAL A N   1 
ATOM   707   C  CA  . VAL A 1 120 ? 114.340 168.089 125.233 1.00 65.09  ? 113 VAL A CA  1 
ATOM   708   C  C   . VAL A 1 120 ? 115.717 167.799 124.659 1.00 65.09  ? 113 VAL A C   1 
ATOM   709   O  O   . VAL A 1 120 ? 115.857 166.992 123.735 1.00 65.09  ? 113 VAL A O   1 
ATOM   710   C  CB  . VAL A 1 120 ? 114.260 167.702 126.720 1.00 65.09  ? 113 VAL A CB  1 
ATOM   711   C  CG1 . VAL A 1 120 ? 112.813 167.622 127.162 1.00 65.09  ? 113 VAL A CG1 1 
ATOM   712   C  CG2 . VAL A 1 120 ? 114.956 166.373 126.957 1.00 65.09  ? 113 VAL A CG2 1 
ATOM   713   N  N   . GLU A 1 121 ? 116.741 168.459 125.191 1.00 58.64  ? 114 GLU A N   1 
ATOM   714   C  CA  . GLU A 1 121 ? 118.122 168.180 124.819 1.00 58.64  ? 114 GLU A CA  1 
ATOM   715   C  C   . GLU A 1 121 ? 118.953 168.087 126.087 1.00 58.64  ? 114 GLU A C   1 
ATOM   716   O  O   . GLU A 1 121 ? 119.146 169.091 126.778 1.00 58.64  ? 114 GLU A O   1 
ATOM   717   C  CB  . GLU A 1 121 ? 118.676 169.261 123.888 1.00 58.64  ? 114 GLU A CB  1 
ATOM   718   C  CG  . GLU A 1 121 ? 120.179 169.191 123.685 1.00 58.64  ? 114 GLU A CG  1 
ATOM   719   C  CD  . GLU A 1 121 ? 120.662 170.133 122.602 1.00 58.64  ? 114 GLU A CD  1 
ATOM   720   O  OE1 . GLU A 1 121 ? 120.077 170.121 121.498 1.00 58.64  ? 114 GLU A OE1 1 
ATOM   721   O  OE2 . GLU A 1 121 ? 121.624 170.888 122.854 1.00 58.64  ? 114 GLU A OE2 1 
ATOM   722   N  N   . ILE A 1 122 ? 119.434 166.886 126.391 1.00 47.50  ? 115 ILE A N   1 
ATOM   723   C  CA  . ILE A 1 122 ? 120.277 166.634 127.554 1.00 47.50  ? 115 ILE A CA  1 
ATOM   724   C  C   . ILE A 1 122 ? 121.580 166.038 127.049 1.00 47.50  ? 115 ILE A C   1 
ATOM   725   O  O   . ILE A 1 122 ? 121.582 164.934 126.493 1.00 47.50  ? 115 ILE A O   1 
ATOM   726   C  CB  . ILE A 1 122 ? 119.603 165.686 128.558 1.00 47.50  ? 115 ILE A CB  1 
ATOM   727   C  CG1 . ILE A 1 122 ? 118.369 166.347 129.174 1.00 47.50  ? 115 ILE A CG1 1 
ATOM   728   C  CG2 . ILE A 1 122 ? 120.597 165.245 129.622 1.00 47.50  ? 115 ILE A CG2 1 
ATOM   729   C  CD1 . ILE A 1 122 ? 118.626 167.032 130.496 1.00 47.50  ? 115 ILE A CD1 1 
ATOM   730   N  N   . SER A 1 123 ? 122.684 166.755 127.237 1.00 46.12  ? 116 SER A N   1 
ATOM   731   C  CA  . SER A 1 123 ? 123.961 166.314 126.688 1.00 46.12  ? 116 SER A CA  1 
ATOM   732   C  C   . SER A 1 123 ? 125.048 166.455 127.739 1.00 46.12  ? 116 SER A C   1 
ATOM   733   O  O   . SER A 1 123 ? 125.384 167.572 128.137 1.00 46.12  ? 116 SER A O   1 
ATOM   734   C  CB  . SER A 1 123 ? 124.325 167.115 125.435 1.00 46.12  ? 116 SER A CB  1 
ATOM   735   O  OG  . SER A 1 123 ? 123.249 167.133 124.514 1.00 46.12  ? 116 SER A OG  1 
ATOM   736   N  N   . LEU A 1 124 ? 125.596 165.328 128.181 1.00 39.08  ? 117 LEU A N   1 
ATOM   737   C  CA  . LEU A 1 124 ? 126.756 165.318 129.062 1.00 39.08  ? 117 LEU A CA  1 
ATOM   738   C  C   . LEU A 1 124 ? 127.988 165.054 128.209 1.00 39.08  ? 117 LEU A C   1 
ATOM   739   O  O   . LEU A 1 124 ? 128.096 163.996 127.581 1.00 39.08  ? 117 LEU A O   1 
ATOM   740   C  CB  . LEU A 1 124 ? 126.610 164.262 130.158 1.00 39.08  ? 117 LEU A CB  1 
ATOM   741   C  CG  . LEU A 1 124 ? 127.636 164.309 131.292 1.00 39.08  ? 117 LEU A CG  1 
ATOM   742   C  CD1 . LEU A 1 124 ? 126.970 164.079 132.636 1.00 39.08  ? 117 LEU A CD1 1 
ATOM   743   C  CD2 . LEU A 1 124 ? 128.732 163.285 131.067 1.00 39.08  ? 117 LEU A CD2 1 
ATOM   744   N  N   . CYS A 1 125 ? 128.909 166.011 128.187 1.00 46.60  ? 118 CYS A N   1 
ATOM   745   C  CA  . CYS A 1 125 ? 130.061 165.956 127.302 1.00 46.60  ? 118 CYS A CA  1 
ATOM   746   C  C   . CYS A 1 125 ? 131.341 166.170 128.093 1.00 46.60  ? 118 CYS A C   1 
ATOM   747   O  O   . CYS A 1 125 ? 131.360 166.877 129.103 1.00 46.60  ? 118 CYS A O   1 
ATOM   748   C  CB  . CYS A 1 125 ? 129.958 167.006 126.189 1.00 46.60  ? 118 CYS A CB  1 
ATOM   749   S  SG  . CYS A 1 125 ? 131.506 167.322 125.318 1.00 46.60  ? 118 CYS A SG  1 
ATOM   750   N  N   . ALA A 1 126 ? 132.413 165.544 127.619 1.00 45.50  ? 119 ALA A N   1 
ATOM   751   C  CA  . ALA A 1 126 ? 133.737 165.698 128.201 1.00 45.50  ? 119 ALA A CA  1 
ATOM   752   C  C   . ALA A 1 126 ? 134.740 165.759 127.057 1.00 45.50  ? 119 ALA A C   1 
ATOM   753   O  O   . ALA A 1 126 ? 134.371 165.921 125.890 1.00 45.50  ? 119 ALA A O   1 
ATOM   754   C  CB  . ALA A 1 126 ? 134.041 164.563 129.186 1.00 45.50  ? 119 ALA A CB  1 
ATOM   755   N  N   . ASP A 1 127 ? 136.021 165.627 127.386 1.00 46.61  ? 120 ASP A N   1 
ATOM   756   C  CA  . ASP A 1 127 ? 137.076 165.662 126.374 1.00 46.61  ? 120 ASP A CA  1 
ATOM   757   C  C   . ASP A 1 127 ? 137.275 164.257 125.802 1.00 46.61  ? 120 ASP A C   1 
ATOM   758   O  O   . ASP A 1 127 ? 138.322 163.626 125.944 1.00 46.61  ? 120 ASP A O   1 
ATOM   759   C  CB  . ASP A 1 127 ? 138.362 166.218 126.968 1.00 46.61  ? 120 ASP A CB  1 
ATOM   760   C  CG  . ASP A 1 127 ? 139.308 166.743 125.913 1.00 46.61  ? 120 ASP A CG  1 
ATOM   761   O  OD1 . ASP A 1 127 ? 138.892 166.850 124.741 1.00 46.61  ? 120 ASP A OD1 1 
ATOM   762   O  OD2 . ASP A 1 127 ? 140.467 167.049 126.256 1.00 46.61  ? 120 ASP A OD2 1 
ATOM   763   N  N   . ILE A 1 128 ? 136.225 163.773 125.135 1.00 42.16  ? 121 ILE A N   1 
ATOM   764   C  CA  . ILE A 1 128 ? 136.245 162.417 124.595 1.00 42.16  ? 121 ILE A CA  1 
ATOM   765   C  C   . ILE A 1 128 ? 137.207 162.265 123.425 1.00 42.16  ? 121 ILE A C   1 
ATOM   766   O  O   . ILE A 1 128 ? 137.777 161.184 123.244 1.00 42.16  ? 121 ILE A O   1 
ATOM   767   C  CB  . ILE A 1 128 ? 134.839 161.974 124.164 1.00 42.16  ? 121 ILE A CB  1 
ATOM   768   C  CG1 . ILE A 1 128 ? 134.145 163.086 123.379 1.00 42.16  ? 121 ILE A CG1 1 
ATOM   769   C  CG2 . ILE A 1 128 ? 134.014 161.573 125.374 1.00 42.16  ? 121 ILE A CG2 1 
ATOM   770   C  CD1 . ILE A 1 128 ? 132.716 162.763 123.007 1.00 42.16  ? 121 ILE A CD1 1 
ATOM   771   N  N   . THR A 1 129 ? 137.406 163.311 122.627 1.00 44.45  ? 122 THR A N   1 
ATOM   772   C  CA  . THR A 1 129 ? 138.274 163.223 121.459 1.00 44.45  ? 122 THR A CA  1 
ATOM   773   C  C   . THR A 1 129 ? 139.750 163.353 121.804 1.00 44.45  ? 122 THR A C   1 
ATOM   774   O  O   . THR A 1 129 ? 140.586 163.269 120.898 1.00 44.45  ? 122 THR A O   1 
ATOM   775   C  CB  . THR A 1 129 ? 137.898 164.297 120.435 1.00 44.45  ? 122 THR A CB  1 
ATOM   776   O  OG1 . THR A 1 129 ? 138.037 165.594 121.026 1.00 44.45  ? 122 THR A OG1 1 
ATOM   777   C  CG2 . THR A 1 129 ? 136.465 164.109 119.968 1.00 44.45  ? 122 THR A CG2 1 
ATOM   778   N  N   . ARG A 1 130 ? 140.071 163.547 123.089 1.00 41.11  ? 123 ARG A N   1 
ATOM   779   C  CA  . ARG A 1 130 ? 141.487 163.687 123.537 1.00 41.11  ? 123 ARG A CA  1 
ATOM   780   C  C   . ARG A 1 130 ? 142.148 164.861 122.790 1.00 41.11  ? 123 ARG A C   1 
ATOM   781   O  O   . ARG A 1 130 ? 143.324 164.714 122.392 1.00 41.11  ? 123 ARG A O   1 
ATOM   782   C  CB  . ARG A 1 130 ? 142.253 162.367 123.367 1.00 41.11  ? 123 ARG A CB  1 
ATOM   783   C  CG  . ARG A 1 130 ? 141.646 161.189 124.118 1.00 41.11  ? 123 ARG A CG  1 
ATOM   784   C  CD  . ARG A 1 130 ? 141.351 159.990 123.226 1.00 41.11  ? 123 ARG A CD  1 
ATOM   785   N  NE  . ARG A 1 130 ? 140.856 158.831 123.978 1.00 41.11  ? 123 ARG A NE  1 
ATOM   786   C  CZ  . ARG A 1 130 ? 141.162 157.565 123.714 1.00 41.11  ? 123 ARG A CZ  1 
ATOM   787   N  NH1 . ARG A 1 130 ? 140.452 156.585 124.244 1.00 41.11  ? 123 ARG A NH1 1 
ATOM   788   N  NH2 . ARG A 1 130 ? 142.178 157.283 122.918 1.00 41.11  ? 123 ARG A NH2 1 
ATOM   789   N  N   . THR A 1 131 ? 141.429 165.973 122.614 1.00 48.47  ? 124 THR A N   1 
ATOM   790   C  CA  . THR A 1 131 ? 141.945 167.163 121.948 1.00 48.47  ? 124 THR A CA  1 
ATOM   791   C  C   . THR A 1 131 ? 142.198 168.318 122.901 1.00 48.47  ? 124 THR A C   1 
ATOM   792   O  O   . THR A 1 131 ? 143.280 168.909 122.873 1.00 48.47  ? 124 THR A O   1 
ATOM   793   C  CB  . THR A 1 131 ? 140.973 167.618 120.852 1.00 48.47  ? 124 THR A CB  1 
ATOM   794   O  OG1 . THR A 1 131 ? 141.062 166.726 119.734 1.00 48.47  ? 124 THR A OG1 1 
ATOM   795   C  CG2 . THR A 1 131 ? 141.303 169.030 120.391 1.00 48.47  ? 124 THR A CG2 1 
ATOM   796   N  N   . GLY A 1 132 ? 141.233 168.648 123.754 1.00 55.19  ? 125 GLY A N   1 
ATOM   797   C  CA  . GLY A 1 132 ? 141.395 169.734 124.698 1.00 55.19  ? 125 GLY A CA  1 
ATOM   798   C  C   . GLY A 1 132 ? 140.216 170.683 124.708 1.00 55.19  ? 125 GLY A C   1 
ATOM   799   O  O   . GLY A 1 132 ? 140.267 171.743 125.339 1.00 55.19  ? 125 GLY A O   1 
ATOM   800   N  N   . LYS A 1 133 ? 139.144 170.311 124.012 1.00 63.96  ? 126 LYS A N   1 
ATOM   801   C  CA  . LYS A 1 133 ? 137.950 171.136 123.904 1.00 63.96  ? 126 LYS A CA  1 
ATOM   802   C  C   . LYS A 1 133 ? 136.727 170.314 124.279 1.00 63.96  ? 126 LYS A C   1 
ATOM   803   O  O   . LYS A 1 133 ? 136.632 169.133 123.933 1.00 63.96  ? 126 LYS A O   1 
ATOM   804   C  CB  . LYS A 1 133 ? 137.785 171.697 122.486 1.00 63.96  ? 126 LYS A CB  1 
ATOM   805   C  CG  . LYS A 1 133 ? 139.004 172.437 121.963 1.00 63.96  ? 126 LYS A CG  1 
ATOM   806   C  CD  . LYS A 1 133 ? 138.779 172.944 120.549 1.00 63.96  ? 126 LYS A CD  1 
ATOM   807   C  CE  . LYS A 1 133 ? 140.005 173.672 120.024 1.00 63.96  ? 126 LYS A CE  1 
ATOM   808   N  NZ  . LYS A 1 133 ? 139.777 174.234 118.664 1.00 63.96  ? 126 LYS A NZ  1 
ATOM   809   N  N   . VAL A 1 134 ? 135.795 170.944 124.987 1.00 57.11  ? 127 VAL A N   1 
ATOM   810   C  CA  . VAL A 1 134 ? 134.570 170.274 125.401 1.00 57.11  ? 127 VAL A CA  1 
ATOM   811   C  C   . VAL A 1 134 ? 133.377 170.840 124.642 1.00 57.11  ? 127 VAL A C   1 
ATOM   812   O  O   . VAL A 1 134 ? 133.419 170.986 123.421 1.00 57.11  ? 127 VAL A O   1 
ATOM   813   C  CB  . VAL A 1 134 ? 134.355 170.396 126.917 1.00 57.11  ? 127 VAL A CB  1 
ATOM   814   C  CG1 . VAL A 1 134 ? 135.636 170.064 127.661 1.00 57.11  ? 127 VAL A CG1 1 
ATOM   815   C  CG2 . VAL A 1 134 ? 133.876 171.792 127.269 1.00 57.11  ? 127 VAL A CG2 1 
ATOM   816   N  N   . GLN A 1 143 ? 130.615 154.129 121.237 1.00 58.59  ? 136 GLN A N   1 
ATOM   817   C  CA  . GLN A 1 143 ? 130.321 155.263 122.104 1.00 58.59  ? 136 GLN A CA  1 
ATOM   818   C  C   . GLN A 1 143 ? 130.137 154.800 123.546 1.00 58.59  ? 136 GLN A C   1 
ATOM   819   O  O   . GLN A 1 143 ? 129.805 153.640 123.793 1.00 58.59  ? 136 GLN A O   1 
ATOM   820   C  CB  . GLN A 1 143 ? 129.071 156.000 121.618 1.00 58.59  ? 136 GLN A CB  1 
ATOM   821   C  CG  . GLN A 1 143 ? 129.259 156.745 120.304 1.00 58.59  ? 136 GLN A CG  1 
ATOM   822   C  CD  . GLN A 1 143 ? 129.956 158.081 120.475 1.00 58.59  ? 136 GLN A CD  1 
ATOM   823   O  OE1 . GLN A 1 143 ? 131.099 158.147 120.927 1.00 58.59  ? 136 GLN A OE1 1 
ATOM   824   N  NE2 . GLN A 1 143 ? 129.268 159.157 120.110 1.00 58.59  ? 136 GLN A NE2 1 
ATOM   825   N  N   . ARG A 1 144 ? 130.355 155.718 124.491 1.00 52.58  ? 137 ARG A N   1 
ATOM   826   C  CA  . ARG A 1 144 ? 130.261 155.430 125.923 1.00 52.58  ? 137 ARG A CA  1 
ATOM   827   C  C   . ARG A 1 144 ? 131.174 154.276 126.333 1.00 52.58  ? 137 ARG A C   1 
ATOM   828   O  O   . ARG A 1 144 ? 130.829 153.477 127.206 1.00 52.58  ? 137 ARG A O   1 
ATOM   829   C  CB  . ARG A 1 144 ? 128.816 155.142 126.343 1.00 52.58  ? 137 ARG A CB  1 
ATOM   830   C  CG  . ARG A 1 144 ? 127.767 155.971 125.614 1.00 52.58  ? 137 ARG A CG  1 
ATOM   831   C  CD  . ARG A 1 144 ? 126.389 155.334 125.721 1.00 52.58  ? 137 ARG A CD  1 
ATOM   832   N  NE  . ARG A 1 144 ? 125.335 156.212 125.224 1.00 52.58  ? 137 ARG A NE  1 
ATOM   833   C  CZ  . ARG A 1 144 ? 124.291 155.804 124.515 1.00 52.58  ? 137 ARG A CZ  1 
ATOM   834   N  NH1 . ARG A 1 144 ? 124.128 154.531 124.195 1.00 52.58  ? 137 ARG A NH1 1 
ATOM   835   N  NH2 . ARG A 1 144 ? 123.388 156.696 124.118 1.00 52.58  ? 137 ARG A NH2 1 
ATOM   836   N  N   . THR A 1 145 ? 132.342 154.176 125.701 1.00 45.74  ? 138 THR A N   1 
ATOM   837   C  CA  . THR A 1 145 ? 133.316 153.142 126.020 1.00 45.74  ? 138 THR A CA  1 
ATOM   838   C  C   . THR A 1 145 ? 134.707 153.674 125.712 1.00 45.74  ? 138 THR A C   1 
ATOM   839   O  O   . THR A 1 145 ? 134.888 154.481 124.798 1.00 45.74  ? 138 THR A O   1 
ATOM   840   C  CB  . THR A 1 145 ? 133.058 151.850 125.232 1.00 45.74  ? 138 THR A CB  1 
ATOM   841   O  OG1 . THR A 1 145 ? 131.652 151.580 125.194 1.00 45.74  ? 138 THR A OG1 1 
ATOM   842   C  CG2 . THR A 1 145 ? 133.770 150.675 125.885 1.00 45.74  ? 138 THR A CG2 1 
ATOM   843   N  N   . TRP A 1 146 ? 135.691 153.211 126.480 1.00 34.60  ? 139 TRP A N   1 
ATOM   844   C  CA  . TRP A 1 146 ? 137.072 153.664 126.348 1.00 34.60  ? 139 TRP A CA  1 
ATOM   845   C  C   . TRP A 1 146 ? 137.845 152.640 125.529 1.00 34.60  ? 139 TRP A C   1 
ATOM   846   O  O   . TRP A 1 146 ? 138.016 151.494 125.957 1.00 34.60  ? 139 TRP A O   1 
ATOM   847   C  CB  . TRP A 1 146 ? 137.714 153.862 127.718 1.00 34.60  ? 139 TRP A CB  1 
ATOM   848   C  CG  . TRP A 1 146 ? 138.729 154.955 127.742 1.00 34.60  ? 139 TRP A CG  1 
ATOM   849   C  CD1 . TRP A 1 146 ? 138.517 156.256 128.076 1.00 34.60  ? 139 TRP A CD1 1 
ATOM   850   C  CD2 . TRP A 1 146 ? 140.118 154.845 127.417 1.00 34.60  ? 139 TRP A CD2 1 
ATOM   851   N  NE1 . TRP A 1 146 ? 139.686 156.967 127.977 1.00 34.60  ? 139 TRP A NE1 1 
ATOM   852   C  CE2 . TRP A 1 146 ? 140.685 156.122 127.575 1.00 34.60  ? 139 TRP A CE2 1 
ATOM   853   C  CE3 . TRP A 1 146 ? 140.937 153.792 127.010 1.00 34.60  ? 139 TRP A CE3 1 
ATOM   854   C  CZ2 . TRP A 1 146 ? 142.029 156.373 127.341 1.00 34.60  ? 139 TRP A CZ2 1 
ATOM   855   C  CZ3 . TRP A 1 146 ? 142.271 154.044 126.778 1.00 34.60  ? 139 TRP A CZ3 1 
ATOM   856   C  CH2 . TRP A 1 146 ? 142.804 155.323 126.944 1.00 34.60  ? 139 TRP A CH2 1 
ATOM   857   N  N   . THR A 1 147 ? 138.313 153.054 124.356 1.00 38.22  ? 140 THR A N   1 
ATOM   858   C  CA  . THR A 1 147 ? 139.086 152.201 123.464 1.00 38.22  ? 140 THR A CA  1 
ATOM   859   C  C   . THR A 1 147 ? 140.424 152.862 123.171 1.00 38.22  ? 140 THR A C   1 
ATOM   860   O  O   . THR A 1 147 ? 140.467 154.031 122.775 1.00 38.22  ? 140 THR A O   1 
ATOM   861   C  CB  . THR A 1 147 ? 138.334 151.944 122.156 1.00 38.22  ? 140 THR A CB  1 
ATOM   862   O  OG1 . THR A 1 147 ? 138.369 153.125 121.347 1.00 38.22  ? 140 THR A OG1 1 
ATOM   863   C  CG2 . THR A 1 147 ? 136.887 151.573 122.433 1.00 38.22  ? 140 THR A CG2 1 
ATOM   864   N  N   . TRP A 1 148 ? 141.507 152.112 123.355 1.00 35.48  ? 141 TRP A N   1 
ATOM   865   C  CA  . TRP A 1 148 ? 142.837 152.633 123.088 1.00 35.48  ? 141 TRP A CA  1 
ATOM   866   C  C   . TRP A 1 148 ? 143.021 152.882 121.592 1.00 35.48  ? 141 TRP A C   1 
ATOM   867   O  O   . TRP A 1 148 ? 142.179 152.531 120.762 1.00 35.48  ? 141 TRP A O   1 
ATOM   868   C  CB  . TRP A 1 148 ? 143.906 151.662 123.584 1.00 35.48  ? 141 TRP A CB  1 
ATOM   869   C  CG  . TRP A 1 148 ? 143.908 151.432 125.063 1.00 35.48  ? 141 TRP A CG  1 
ATOM   870   C  CD1 . TRP A 1 148 ? 143.002 150.711 125.780 1.00 35.48  ? 141 TRP A CD1 1 
ATOM   871   C  CD2 . TRP A 1 148 ? 144.882 151.900 126.004 1.00 35.48  ? 141 TRP A CD2 1 
ATOM   872   N  NE1 . TRP A 1 148 ? 143.342 150.712 127.110 1.00 35.48  ? 141 TRP A NE1 1 
ATOM   873   C  CE2 . TRP A 1 148 ? 144.494 151.434 127.272 1.00 35.48  ? 141 TRP A CE2 1 
ATOM   874   C  CE3 . TRP A 1 148 ? 146.041 152.673 125.897 1.00 35.48  ? 141 TRP A CE3 1 
ATOM   875   C  CZ2 . TRP A 1 148 ? 145.222 151.716 128.424 1.00 35.48  ? 141 TRP A CZ2 1 
ATOM   876   C  CZ3 . TRP A 1 148 ? 146.761 152.950 127.040 1.00 35.48  ? 141 TRP A CZ3 1 
ATOM   877   C  CH2 . TRP A 1 148 ? 146.350 152.475 128.286 1.00 35.48  ? 141 TRP A CH2 1 
ATOM   878   N  N   . GLY A 1 149 ? 144.150 153.496 121.249 1.00 37.39  ? 142 GLY A N   1 
ATOM   879   C  CA  . GLY A 1 149 ? 144.515 153.693 119.867 1.00 37.39  ? 142 GLY A CA  1 
ATOM   880   C  C   . GLY A 1 149 ? 144.237 155.095 119.365 1.00 37.39  ? 142 GLY A C   1 
ATOM   881   O  O   . GLY A 1 149 ? 143.447 155.846 119.945 1.00 37.39  ? 142 GLY A O   1 
ATOM   882   N  N   . PRO A 1 150 ? 144.890 155.472 118.262 1.00 44.32  ? 143 PRO A N   1 
ATOM   883   C  CA  . PRO A 1 150 ? 144.693 156.823 117.715 1.00 44.32  ? 143 PRO A CA  1 
ATOM   884   C  C   . PRO A 1 150 ? 143.284 157.089 117.217 1.00 44.32  ? 143 PRO A C   1 
ATOM   885   O  O   . PRO A 1 150 ? 142.909 158.259 117.078 1.00 44.32  ? 143 PRO A O   1 
ATOM   886   C  CB  . PRO A 1 150 ? 145.709 156.889 116.567 1.00 44.32  ? 143 PRO A CB  1 
ATOM   887   C  CG  . PRO A 1 150 ? 145.940 155.465 116.189 1.00 44.32  ? 143 PRO A CG  1 
ATOM   888   C  CD  . PRO A 1 150 ? 145.843 154.683 117.464 1.00 44.32  ? 143 PRO A CD  1 
ATOM   889   N  N   . CYS A 1 151 ? 142.496 156.055 116.936 1.00 49.65  ? 144 CYS A N   1 
ATOM   890   C  CA  . CYS A 1 151 ? 141.127 156.222 116.470 1.00 49.65  ? 144 CYS A CA  1 
ATOM   891   C  C   . CYS A 1 151 ? 140.104 156.060 117.587 1.00 49.65  ? 144 CYS A C   1 
ATOM   892   O  O   . CYS A 1 151 ? 138.900 156.049 117.315 1.00 49.65  ? 144 CYS A O   1 
ATOM   893   C  CB  . CYS A 1 151 ? 140.831 155.233 115.341 1.00 49.65  ? 144 CYS A CB  1 
ATOM   894   S  SG  . CYS A 1 151 ? 140.272 153.602 115.888 1.00 49.65  ? 144 CYS A SG  1 
ATOM   895   N  N   . GLY A 1 152 ? 140.553 155.943 118.835 1.00 46.57  ? 145 GLY A N   1 
ATOM   896   C  CA  . GLY A 1 152 ? 139.670 155.697 119.954 1.00 46.57  ? 145 GLY A CA  1 
ATOM   897   C  C   . GLY A 1 152 ? 139.000 156.957 120.465 1.00 46.57  ? 145 GLY A C   1 
ATOM   898   O  O   . GLY A 1 152 ? 139.135 158.047 119.908 1.00 46.57  ? 145 GLY A O   1 
ATOM   899   N  N   . GLN A 1 153 ? 138.257 156.788 121.558 1.00 45.62  ? 146 GLN A N   1 
ATOM   900   C  CA  . GLN A 1 153 ? 137.542 157.887 122.188 1.00 45.62  ? 146 GLN A CA  1 
ATOM   901   C  C   . GLN A 1 153 ? 137.424 157.614 123.679 1.00 45.62  ? 146 GLN A C   1 
ATOM   902   O  O   . GLN A 1 153 ? 137.291 156.464 124.104 1.00 45.62  ? 146 GLN A O   1 
ATOM   903   C  CB  . GLN A 1 153 ? 136.152 158.079 121.571 1.00 45.62  ? 146 GLN A CB  1 
ATOM   904   C  CG  . GLN A 1 153 ? 136.118 159.062 120.414 1.00 45.62  ? 146 GLN A CG  1 
ATOM   905   C  CD  . GLN A 1 153 ? 134.973 158.796 119.459 1.00 45.62  ? 146 GLN A CD  1 
ATOM   906   O  OE1 . GLN A 1 153 ? 133.928 158.281 119.855 1.00 45.62  ? 146 GLN A OE1 1 
ATOM   907   N  NE2 . GLN A 1 153 ? 135.165 159.145 118.193 1.00 45.62  ? 146 GLN A NE2 1 
ATOM   908   N  N   . GLY A 1 154 ? 137.473 158.684 124.471 1.00 40.96  ? 147 GLY A N   1 
ATOM   909   C  CA  . GLY A 1 154 ? 137.382 158.569 125.915 1.00 40.96  ? 147 GLY A CA  1 
ATOM   910   C  C   . GLY A 1 154 ? 138.322 159.508 126.644 1.00 40.96  ? 147 GLY A C   1 
ATOM   911   O  O   . GLY A 1 154 ? 139.489 159.635 126.264 1.00 40.96  ? 147 GLY A O   1 
ATOM   912   N  N   . ALA A 1 155 ? 137.836 160.159 127.696 1.00 33.22  ? 148 ALA A N   1 
ATOM   913   C  CA  . ALA A 1 155 ? 138.591 161.206 128.366 1.00 33.22  ? 148 ALA A CA  1 
ATOM   914   C  C   . ALA A 1 155 ? 139.477 160.640 129.476 1.00 33.22  ? 148 ALA A C   1 
ATOM   915   O  O   . ALA A 1 155 ? 139.387 159.470 129.856 1.00 33.22  ? 148 ALA A O   1 
ATOM   916   C  CB  . ALA A 1 155 ? 137.645 162.265 128.925 1.00 33.22  ? 148 ALA A CB  1 
ATOM   917   N  N   . ILE A 1 156 ? 140.340 161.505 130.008 1.00 29.84  ? 149 ILE A N   1 
ATOM   918   C  CA  . ILE A 1 156 ? 141.373 161.112 130.958 1.00 29.84  ? 149 ILE A CA  1 
ATOM   919   C  C   . ILE A 1 156 ? 141.282 161.990 132.199 1.00 29.84  ? 149 ILE A C   1 
ATOM   920   O  O   . ILE A 1 156 ? 141.195 163.218 132.092 1.00 29.84  ? 149 ILE A O   1 
ATOM   921   C  CB  . ILE A 1 156 ? 142.783 161.209 130.345 1.00 29.84  ? 149 ILE A CB  1 
ATOM   922   C  CG1 . ILE A 1 156 ? 142.866 160.429 129.033 1.00 29.84  ? 149 ILE A CG1 1 
ATOM   923   C  CG2 . ILE A 1 156 ? 143.822 160.711 131.329 1.00 29.84  ? 149 ILE A CG2 1 
ATOM   924   C  CD1 . ILE A 1 156 ? 142.641 161.272 127.804 1.00 29.84  ? 149 ILE A CD1 1 
ATOM   925   N  N   . LEU A 1 157 ? 141.305 161.360 133.368 1.00 30.42  ? 150 LEU A N   1 
ATOM   926   C  CA  . LEU A 1 157 ? 141.463 162.035 134.648 1.00 30.42  ? 150 LEU A CA  1 
ATOM   927   C  C   . LEU A 1 157 ? 142.919 162.063 135.080 1.00 30.42  ? 150 LEU A C   1 
ATOM   928   O  O   . LEU A 1 157 ? 143.753 161.285 134.613 1.00 30.42  ? 150 LEU A O   1 
ATOM   929   C  CB  . LEU A 1 157 ? 140.627 161.367 135.743 1.00 30.42  ? 150 LEU A CB  1 
ATOM   930   C  CG  . LEU A 1 157 ? 139.110 161.399 135.618 1.00 30.42  ? 150 LEU A CG  1 
ATOM   931   C  CD1 . LEU A 1 157 ? 138.472 160.585 136.684 1.00 30.42  ? 150 LEU A CD1 1 
ATOM   932   C  CD2 . LEU A 1 157 ? 138.629 162.836 135.699 1.00 30.42  ? 150 LEU A CD2 1 
ATOM   933   N  N   . LEU A 1 158 ? 143.208 162.979 135.995 1.00 30.68  ? 151 LEU A N   1 
ATOM   934   C  CA  . LEU A 1 158 ? 144.524 163.117 136.591 1.00 30.68  ? 151 LEU A CA  1 
ATOM   935   C  C   . LEU A 1 158 ? 144.398 162.962 138.098 1.00 30.68  ? 151 LEU A C   1 
ATOM   936   O  O   . LEU A 1 158 ? 143.551 163.604 138.727 1.00 30.68  ? 151 LEU A O   1 
ATOM   937   C  CB  . LEU A 1 158 ? 145.134 164.477 136.258 1.00 30.68  ? 151 LEU A CB  1 
ATOM   938   C  CG  . LEU A 1 158 ? 146.133 164.486 135.108 1.00 30.68  ? 151 LEU A CG  1 
ATOM   939   C  CD1 . LEU A 1 158 ? 146.229 165.876 134.516 1.00 30.68  ? 151 LEU A CD1 1 
ATOM   940   C  CD2 . LEU A 1 158 ? 147.476 163.993 135.568 1.00 30.68  ? 151 LEU A CD2 1 
ATOM   941   N  N   . VAL A 1 159 ? 145.232 162.108 138.676 1.00 34.24  ? 152 VAL A N   1 
ATOM   942   C  CA  . VAL A 1 159 ? 145.230 161.919 140.121 1.00 34.24  ? 152 VAL A CA  1 
ATOM   943   C  C   . VAL A 1 159 ? 145.766 163.189 140.766 1.00 34.24  ? 152 VAL A C   1 
ATOM   944   O  O   . VAL A 1 159 ? 146.923 163.564 140.556 1.00 34.24  ? 152 VAL A O   1 
ATOM   945   C  CB  . VAL A 1 159 ? 146.066 160.699 140.524 1.00 34.24  ? 152 VAL A CB  1 
ATOM   946   C  CG1 . VAL A 1 159 ? 146.108 160.569 142.034 1.00 34.24  ? 152 VAL A CG1 1 
ATOM   947   C  CG2 . VAL A 1 159 ? 145.503 159.447 139.889 1.00 34.24  ? 152 VAL A CG2 1 
ATOM   948   N  N   . ASN A 1 160 ? 144.924 163.859 141.549 1.00 39.96  ? 153 ASN A N   1 
ATOM   949   C  CA  . ASN A 1 160 ? 145.311 165.106 142.204 1.00 39.96  ? 153 ASN A CA  1 
ATOM   950   C  C   . ASN A 1 160 ? 146.218 164.758 143.379 1.00 39.96  ? 153 ASN A C   1 
ATOM   951   O  O   . ASN A 1 160 ? 145.805 164.708 144.538 1.00 39.96  ? 153 ASN A O   1 
ATOM   952   C  CB  . ASN A 1 160 ? 144.080 165.882 142.650 1.00 39.96  ? 153 ASN A CB  1 
ATOM   953   C  CG  . ASN A 1 160 ? 144.253 167.375 142.508 1.00 39.96  ? 153 ASN A CG  1 
ATOM   954   O  OD1 . ASN A 1 160 ? 145.212 167.953 143.015 1.00 39.96  ? 153 ASN A OD1 1 
ATOM   955   N  ND2 . ASN A 1 160 ? 143.322 168.012 141.811 1.00 39.96  ? 153 ASN A ND2 1 
ATOM   956   N  N   . CYS A 1 161 ? 147.487 164.507 143.062 1.00 40.16  ? 154 CYS A N   1 
ATOM   957   C  CA  . CYS A 1 161 ? 148.469 164.098 144.055 1.00 40.16  ? 154 CYS A CA  1 
ATOM   958   C  C   . CYS A 1 161 ? 149.436 165.213 144.430 1.00 40.16  ? 154 CYS A C   1 
ATOM   959   O  O   . CYS A 1 161 ? 150.432 164.949 145.109 1.00 40.16  ? 154 CYS A O   1 
ATOM   960   C  CB  . CYS A 1 161 ? 149.249 162.881 143.557 1.00 40.16  ? 154 CYS A CB  1 
ATOM   961   S  SG  . CYS A 1 161 ? 149.696 162.938 141.812 1.00 40.16  ? 154 CYS A SG  1 
ATOM   962   N  N   . ASP A 1 162 ? 149.172 166.445 144.013 1.00 46.07  ? 155 ASP A N   1 
ATOM   963   C  CA  . ASP A 1 162 ? 150.038 167.567 144.330 1.00 46.07  ? 155 ASP A CA  1 
ATOM   964   C  C   . ASP A 1 162 ? 149.447 168.379 145.480 1.00 46.07  ? 155 ASP A C   1 
ATOM   965   O  O   . ASP A 1 162 ? 148.415 168.033 146.057 1.00 46.07  ? 155 ASP A O   1 
ATOM   966   C  CB  . ASP A 1 162 ? 150.265 168.434 143.088 1.00 46.07  ? 155 ASP A CB  1 
ATOM   967   C  CG  . ASP A 1 162 ? 148.986 169.073 142.571 1.00 46.07  ? 155 ASP A CG  1 
ATOM   968   O  OD1 . ASP A 1 162 ? 147.900 168.785 143.112 1.00 46.07  ? 155 ASP A OD1 1 
ATOM   969   O  OD2 . ASP A 1 162 ? 149.069 169.872 141.615 1.00 46.07  ? 155 ASP A OD2 1 
ATOM   970   N  N   . ARG A 1 163 ? 150.120 169.478 145.818 1.00 52.25  ? 156 ARG A N   1 
ATOM   971   C  CA  . ARG A 1 163 ? 149.640 170.432 146.818 1.00 52.25  ? 156 ARG A CA  1 
ATOM   972   C  C   . ARG A 1 163 ? 149.796 171.840 146.241 1.00 52.25  ? 156 ARG A C   1 
ATOM   973   O  O   . ARG A 1 163 ? 150.879 172.429 146.262 1.00 52.25  ? 156 ARG A O   1 
ATOM   974   C  CB  . ARG A 1 163 ? 150.373 170.260 148.158 1.00 52.25  ? 156 ARG A CB  1 
ATOM   975   C  CG  . ARG A 1 163 ? 151.889 170.329 148.080 1.00 52.25  ? 156 ARG A CG  1 
ATOM   976   C  CD  . ARG A 1 163 ? 152.507 170.802 149.386 1.00 52.25  ? 156 ARG A CD  1 
ATOM   977   N  NE  . ARG A 1 163 ? 152.672 169.730 150.358 1.00 52.25  ? 156 ARG A NE  1 
ATOM   978   C  CZ  . ARG A 1 163 ? 153.653 169.679 151.248 1.00 52.25  ? 156 ARG A CZ  1 
ATOM   979   N  NH1 . ARG A 1 163 ? 154.581 170.620 151.309 1.00 52.25  ? 156 ARG A NH1 1 
ATOM   980   N  NH2 . ARG A 1 163 ? 153.705 168.659 152.100 1.00 52.25  ? 156 ARG A NH2 1 
ATOM   981   N  N   . ASP A 1 164 ? 148.702 172.377 145.701 1.00 54.83  ? 157 ASP A N   1 
ATOM   982   C  CA  . ASP A 1 164 ? 148.703 173.742 145.195 1.00 54.83  ? 157 ASP A CA  1 
ATOM   983   C  C   . ASP A 1 164 ? 148.498 174.776 146.291 1.00 54.83  ? 157 ASP A C   1 
ATOM   984   O  O   . ASP A 1 164 ? 148.588 175.976 146.011 1.00 54.83  ? 157 ASP A O   1 
ATOM   985   C  CB  . ASP A 1 164 ? 147.626 173.910 144.122 1.00 54.83  ? 157 ASP A CB  1 
ATOM   986   C  CG  . ASP A 1 164 ? 147.893 173.065 142.896 1.00 54.83  ? 157 ASP A CG  1 
ATOM   987   O  OD1 . ASP A 1 164 ? 148.741 173.464 142.072 1.00 54.83  ? 157 ASP A OD1 1 
ATOM   988   O  OD2 . ASP A 1 164 ? 147.263 171.997 142.764 1.00 54.83  ? 157 ASP A OD2 1 
ATOM   989   N  N   . ASN A 1 165 ? 148.222 174.346 147.517 1.00 65.80  ? 158 ASN A N   1 
ATOM   990   C  CA  . ASN A 1 165 ? 148.106 175.256 148.646 1.00 65.80  ? 158 ASN A CA  1 
ATOM   991   C  C   . ASN A 1 165 ? 149.450 175.355 149.353 1.00 65.80  ? 158 ASN A C   1 
ATOM   992   O  O   . ASN A 1 165 ? 150.047 174.335 149.711 1.00 65.80  ? 158 ASN A O   1 
ATOM   993   C  CB  . ASN A 1 165 ? 147.028 174.777 149.619 1.00 65.80  ? 158 ASN A CB  1 
ATOM   994   C  CG  . ASN A 1 165 ? 146.588 175.862 150.577 1.00 65.80  ? 158 ASN A CG  1 
ATOM   995   O  OD1 . ASN A 1 165 ? 145.918 175.592 151.573 1.00 65.80  ? 158 ASN A OD1 1 
ATOM   996   N  ND2 . ASN A 1 165 ? 146.960 177.101 150.280 1.00 65.80  ? 158 ASN A ND2 1 
ATOM   997   N  N   . LEU A 1 166 ? 149.922 176.582 149.551 1.00 72.97  ? 159 LEU A N   1 
ATOM   998   C  CA  . LEU A 1 166 ? 151.201 176.825 150.201 1.00 72.97  ? 159 LEU A CA  1 
ATOM   999   C  C   . LEU A 1 166 ? 151.102 176.827 151.720 1.00 72.97  ? 159 LEU A C   1 
ATOM   1000  O  O   . LEU A 1 166 ? 152.137 176.872 152.394 1.00 72.97  ? 159 LEU A O   1 
ATOM   1001  C  CB  . LEU A 1 166 ? 151.788 178.156 149.721 1.00 72.97  ? 159 LEU A CB  1 
ATOM   1002  C  CG  . LEU A 1 166 ? 152.090 178.248 148.225 1.00 72.97  ? 159 LEU A CG  1 
ATOM   1003  C  CD1 . LEU A 1 166 ? 152.940 179.470 147.925 1.00 72.97  ? 159 LEU A CD1 1 
ATOM   1004  C  CD2 . LEU A 1 166 ? 152.777 176.983 147.742 1.00 72.97  ? 159 LEU A CD2 1 
ATOM   1005  N  N   . GLU A 1 167 ? 149.890 176.779 152.274 1.00 74.33  ? 160 GLU A N   1 
ATOM   1006  C  CA  . GLU A 1 167 ? 149.687 176.751 153.717 1.00 74.33  ? 160 GLU A CA  1 
ATOM   1007  C  C   . GLU A 1 167 ? 149.031 175.452 154.170 1.00 74.33  ? 160 GLU A C   1 
ATOM   1008  O  O   . GLU A 1 167 ? 148.463 175.393 155.265 1.00 74.33  ? 160 GLU A O   1 
ATOM   1009  C  CB  . GLU A 1 167 ? 148.854 177.957 154.161 1.00 74.33  ? 160 GLU A CB  1 
ATOM   1010  C  CG  . GLU A 1 167 ? 149.146 178.440 155.576 1.00 74.33  ? 160 GLU A CG  1 
ATOM   1011  C  CD  . GLU A 1 167 ? 150.501 179.113 155.703 1.00 74.33  ? 160 GLU A CD  1 
ATOM   1012  O  OE1 . GLU A 1 167 ? 151.133 179.397 154.663 1.00 74.33  ? 160 GLU A OE1 1 
ATOM   1013  O  OE2 . GLU A 1 167 ? 150.936 179.359 156.848 1.00 74.33  ? 160 GLU A OE2 1 
ATOM   1014  N  N   . SER A 1 168 ? 149.101 174.409 153.351 1.00 69.09  ? 161 SER A N   1 
ATOM   1015  C  CA  . SER A 1 168 ? 148.517 173.114 153.661 1.00 69.09  ? 161 SER A CA  1 
ATOM   1016  C  C   . SER A 1 168 ? 149.620 172.069 153.765 1.00 69.09  ? 161 SER A C   1 
ATOM   1017  O  O   . SER A 1 168 ? 150.722 172.236 153.238 1.00 69.09  ? 161 SER A O   1 
ATOM   1018  C  CB  . SER A 1 168 ? 147.490 172.703 152.599 1.00 69.09  ? 161 SER A CB  1 
ATOM   1019  O  OG  . SER A 1 168 ? 146.319 173.496 152.686 1.00 69.09  ? 161 SER A OG  1 
ATOM   1020  N  N   . SER A 1 169 ? 149.308 170.977 154.461 1.00 64.31  ? 162 SER A N   1 
ATOM   1021  C  CA  . SER A 1 169 ? 150.246 169.878 154.664 1.00 64.31  ? 162 SER A CA  1 
ATOM   1022  C  C   . SER A 1 169 ? 149.547 168.553 154.355 1.00 64.31  ? 162 SER A C   1 
ATOM   1023  O  O   . SER A 1 169 ? 149.637 167.581 155.103 1.00 64.31  ? 162 SER A O   1 
ATOM   1024  C  CB  . SER A 1 169 ? 150.804 169.891 156.085 1.00 64.31  ? 162 SER A CB  1 
ATOM   1025  O  OG  . SER A 1 169 ? 149.759 169.915 157.041 1.00 64.31  ? 162 SER A OG  1 
ATOM   1026  N  N   . ALA A 1 170 ? 148.838 168.522 153.229 1.00 56.36  ? 163 ALA A N   1 
ATOM   1027  C  CA  . ALA A 1 170 ? 148.120 167.324 152.823 1.00 56.36  ? 163 ALA A CA  1 
ATOM   1028  C  C   . ALA A 1 170 ? 147.937 167.340 151.315 1.00 56.36  ? 163 ALA A C   1 
ATOM   1029  O  O   . ALA A 1 170 ? 147.818 168.409 150.713 1.00 56.36  ? 163 ALA A O   1 
ATOM   1030  C  CB  . ALA A 1 170 ? 146.760 167.226 153.522 1.00 56.36  ? 163 ALA A CB  1 
ATOM   1031  N  N   . MET A 1 171 ? 147.925 166.151 150.714 1.00 53.33  ? 164 MET A N   1 
ATOM   1032  C  CA  . MET A 1 171 ? 147.580 166.036 149.305 1.00 53.33  ? 164 MET A CA  1 
ATOM   1033  C  C   . MET A 1 171 ? 146.159 166.538 149.095 1.00 53.33  ? 164 MET A C   1 
ATOM   1034  O  O   . MET A 1 171 ? 145.245 166.175 149.840 1.00 53.33  ? 164 MET A O   1 
ATOM   1035  C  CB  . MET A 1 171 ? 147.721 164.587 148.839 1.00 53.33  ? 164 MET A CB  1 
ATOM   1036  C  CG  . MET A 1 171 ? 149.133 164.224 148.401 1.00 53.33  ? 164 MET A CG  1 
ATOM   1037  S  SD  . MET A 1 171 ? 149.275 162.679 147.475 1.00 53.33  ? 164 MET A SD  1 
ATOM   1038  C  CE  . MET A 1 171 ? 147.562 162.191 147.318 1.00 53.33  ? 164 MET A CE  1 
ATOM   1039  N  N   . ASP A 1 172 ? 145.972 167.370 148.073 1.00 53.82  ? 165 ASP A N   1 
ATOM   1040  C  CA  . ASP A 1 172 ? 144.765 168.182 147.980 1.00 53.82  ? 165 ASP A CA  1 
ATOM   1041  C  C   . ASP A 1 172 ? 143.532 167.359 147.629 1.00 53.82  ? 165 ASP A C   1 
ATOM   1042  O  O   . ASP A 1 172 ? 142.418 167.890 147.603 1.00 53.82  ? 165 ASP A O   1 
ATOM   1043  C  CB  . ASP A 1 172 ? 144.961 169.302 146.959 1.00 53.82  ? 165 ASP A CB  1 
ATOM   1044  C  CG  . ASP A 1 172 ? 144.288 170.593 147.381 1.00 53.82  ? 165 ASP A CG  1 
ATOM   1045  O  OD1 . ASP A 1 172 ? 144.964 171.643 147.382 1.00 53.82  ? 165 ASP A OD1 1 
ATOM   1046  O  OD2 . ASP A 1 172 ? 143.086 170.558 147.715 1.00 53.82  ? 165 ASP A OD2 1 
ATOM   1047  N  N   . CYS A 1 173 ? 143.711 166.068 147.357 1.00 51.54  ? 166 CYS A N   1 
ATOM   1048  C  CA  . CYS A 1 173 ? 142.590 165.173 147.115 1.00 51.54  ? 166 CYS A CA  1 
ATOM   1049  C  C   . CYS A 1 173 ? 142.112 164.474 148.379 1.00 51.54  ? 166 CYS A C   1 
ATOM   1050  O  O   . CYS A 1 173 ? 141.146 163.706 148.318 1.00 51.54  ? 166 CYS A O   1 
ATOM   1051  C  CB  . CYS A 1 173 ? 142.962 164.127 146.060 1.00 51.54  ? 166 CYS A CB  1 
ATOM   1052  S  SG  . CYS A 1 173 ? 144.212 162.952 146.602 1.00 51.54  ? 166 CYS A SG  1 
ATOM   1053  N  N   . GLU A 1 174 ? 142.760 164.717 149.520 1.00 58.18  ? 167 GLU A N   1 
ATOM   1054  C  CA  . GLU A 1 174 ? 142.363 164.088 150.774 1.00 58.18  ? 167 GLU A CA  1 
ATOM   1055  C  C   . GLU A 1 174 ? 141.106 164.702 151.375 1.00 58.18  ? 167 GLU A C   1 
ATOM   1056  O  O   . GLU A 1 174 ? 140.256 163.963 151.884 1.00 58.18  ? 167 GLU A O   1 
ATOM   1057  C  CB  . GLU A 1 174 ? 143.512 164.170 151.782 1.00 58.18  ? 167 GLU A CB  1 
ATOM   1058  C  CG  . GLU A 1 174 ? 143.075 164.341 153.226 1.00 58.18  ? 167 GLU A CG  1 
ATOM   1059  C  CD  . GLU A 1 174 ? 144.246 164.373 154.185 1.00 58.18  ? 167 GLU A CD  1 
ATOM   1060  O  OE1 . GLU A 1 174 ? 145.115 163.480 154.095 1.00 58.18  ? 167 GLU A OE1 1 
ATOM   1061  O  OE2 . GLU A 1 174 ? 144.299 165.291 155.030 1.00 58.18  ? 167 GLU A OE2 1 
ATOM   1062  N  N   . ASP A 1 175 ? 140.963 166.021 151.324 1.00 56.63  ? 168 ASP A N   1 
ATOM   1063  C  CA  . ASP A 1 175 ? 139.819 166.709 151.893 1.00 56.63  ? 168 ASP A CA  1 
ATOM   1064  C  C   . ASP A 1 175 ? 138.689 166.774 150.866 1.00 56.63  ? 168 ASP A C   1 
ATOM   1065  O  O   . ASP A 1 175 ? 138.736 166.130 149.815 1.00 56.63  ? 168 ASP A O   1 
ATOM   1066  C  CB  . ASP A 1 175 ? 140.238 168.096 152.383 1.00 56.63  ? 168 ASP A CB  1 
ATOM   1067  C  CG  . ASP A 1 175 ? 141.033 168.865 151.347 1.00 56.63  ? 168 ASP A CG  1 
ATOM   1068  O  OD1 . ASP A 1 175 ? 141.249 168.330 150.240 1.00 56.63  ? 168 ASP A OD1 1 
ATOM   1069  O  OD2 . ASP A 1 175 ? 141.449 170.004 151.644 1.00 56.63  ? 168 ASP A OD2 1 
ATOM   1070  N  N   . ASP A 1 176 ? 137.658 167.557 151.170 1.00 57.45  ? 169 ASP A N   1 
ATOM   1071  C  CA  . ASP A 1 176 ? 136.490 167.704 150.306 1.00 57.45  ? 169 ASP A CA  1 
ATOM   1072  C  C   . ASP A 1 176 ? 136.223 169.174 150.017 1.00 57.45  ? 169 ASP A C   1 
ATOM   1073  O  O   . ASP A 1 176 ? 135.100 169.665 150.137 1.00 57.45  ? 169 ASP A O   1 
ATOM   1074  C  CB  . ASP A 1 176 ? 135.260 167.045 150.925 1.00 57.45  ? 169 ASP A CB  1 
ATOM   1075  C  CG  . ASP A 1 176 ? 135.096 167.373 152.396 1.00 57.45  ? 169 ASP A CG  1 
ATOM   1076  O  OD1 . ASP A 1 176 ? 135.386 168.520 152.792 1.00 57.45  ? 169 ASP A OD1 1 
ATOM   1077  O  OD2 . ASP A 1 176 ? 134.674 166.480 153.159 1.00 57.45  ? 169 ASP A OD2 1 
ATOM   1078  N  N   . GLU A 1 177 ? 137.270 169.904 149.639 1.00 59.64  ? 170 GLU A N   1 
ATOM   1079  C  CA  . GLU A 1 177 ? 137.132 171.307 149.280 1.00 59.64  ? 170 GLU A CA  1 
ATOM   1080  C  C   . GLU A 1 177 ? 138.203 171.672 148.265 1.00 59.64  ? 170 GLU A C   1 
ATOM   1081  O  O   . GLU A 1 177 ? 139.242 171.015 148.164 1.00 59.64  ? 170 GLU A O   1 
ATOM   1082  C  CB  . GLU A 1 177 ? 137.235 172.224 150.507 1.00 59.64  ? 170 GLU A CB  1 
ATOM   1083  C  CG  . GLU A 1 177 ? 135.922 172.469 151.237 1.00 59.64  ? 170 GLU A CG  1 
ATOM   1084  C  CD  . GLU A 1 177 ? 134.931 173.282 150.421 1.00 59.64  ? 170 GLU A CD  1 
ATOM   1085  O  OE1 . GLU A 1 177 ? 135.343 173.911 149.424 1.00 59.64  ? 170 GLU A OE1 1 
ATOM   1086  O  OE2 . GLU A 1 177 ? 133.735 173.293 150.781 1.00 59.64  ? 170 GLU A OE2 1 
ATOM   1087  N  N   . VAL A 1 178 ? 137.934 172.734 147.512 1.00 56.81  ? 171 VAL A N   1 
ATOM   1088  C  CA  . VAL A 1 178 ? 138.896 173.311 146.581 1.00 56.81  ? 171 VAL A CA  1 
ATOM   1089  C  C   . VAL A 1 178 ? 139.408 174.602 147.200 1.00 56.81  ? 171 VAL A C   1 
ATOM   1090  O  O   . VAL A 1 178 ? 138.655 175.572 147.344 1.00 56.81  ? 171 VAL A O   1 
ATOM   1091  C  CB  . VAL A 1 178 ? 138.264 173.565 145.205 1.00 56.81  ? 171 VAL A CB  1 
ATOM   1092  C  CG1 . VAL A 1 178 ? 139.334 173.893 144.186 1.00 56.81  ? 171 VAL A CG1 1 
ATOM   1093  C  CG2 . VAL A 1 178 ? 137.455 172.360 144.767 1.00 56.81  ? 171 VAL A CG2 1 
ATOM   1094  N  N   . LEU A 1 179 ? 140.688 174.620 147.568 1.00 59.71  ? 172 LEU A N   1 
ATOM   1095  C  CA  . LEU A 1 179 ? 141.236 175.702 148.374 1.00 59.71  ? 172 LEU A CA  1 
ATOM   1096  C  C   . LEU A 1 179 ? 141.898 176.806 147.561 1.00 59.71  ? 172 LEU A C   1 
ATOM   1097  O  O   . LEU A 1 179 ? 142.228 177.850 148.132 1.00 59.71  ? 172 LEU A O   1 
ATOM   1098  C  CB  . LEU A 1 179 ? 142.248 175.149 149.385 1.00 59.71  ? 172 LEU A CB  1 
ATOM   1099  C  CG  . LEU A 1 179 ? 141.694 174.287 150.521 1.00 59.71  ? 172 LEU A CG  1 
ATOM   1100  C  CD1 . LEU A 1 179 ? 140.345 174.813 150.995 1.00 59.71  ? 172 LEU A CD1 1 
ATOM   1101  C  CD2 . LEU A 1 179 ? 141.593 172.826 150.106 1.00 59.71  ? 172 LEU A CD2 1 
ATOM   1102  N  N   . ASP A 1 180 ? 142.100 176.616 146.259 1.00 60.15  ? 173 ASP A N   1 
ATOM   1103  C  CA  . ASP A 1 180 ? 142.754 177.647 145.467 1.00 60.15  ? 173 ASP A CA  1 
ATOM   1104  C  C   . ASP A 1 180 ? 142.422 177.401 144.003 1.00 60.15  ? 173 ASP A C   1 
ATOM   1105  O  O   . ASP A 1 180 ? 142.390 176.253 143.551 1.00 60.15  ? 173 ASP A O   1 
ATOM   1106  C  CB  . ASP A 1 180 ? 144.273 177.643 145.723 1.00 60.15  ? 173 ASP A CB  1 
ATOM   1107  C  CG  . ASP A 1 180 ? 145.062 178.540 144.766 1.00 60.15  ? 173 ASP A CG  1 
ATOM   1108  O  OD1 . ASP A 1 180 ? 144.760 178.617 143.560 1.00 60.15  ? 173 ASP A OD1 1 
ATOM   1109  O  OD2 . ASP A 1 180 ? 146.015 179.190 145.245 1.00 60.15  ? 173 ASP A OD2 1 
ATOM   1110  N  N   . SER A 1 181 ? 142.211 178.495 143.265 1.00 59.94  ? 174 SER A N   1 
ATOM   1111  C  CA  . SER A 1 181 ? 141.790 178.391 141.872 1.00 59.94  ? 174 SER A CA  1 
ATOM   1112  C  C   . SER A 1 181 ? 142.826 177.680 141.013 1.00 59.94  ? 174 SER A C   1 
ATOM   1113  O  O   . SER A 1 181 ? 142.466 177.031 140.025 1.00 59.94  ? 174 SER A O   1 
ATOM   1114  C  CB  . SER A 1 181 ? 141.499 179.782 141.308 1.00 59.94  ? 174 SER A CB  1 
ATOM   1115  O  OG  . SER A 1 181 ? 140.570 180.476 142.120 1.00 59.94  ? 174 SER A OG  1 
ATOM   1116  N  N   . GLU A 1 182 ? 144.111 177.796 141.360 1.00 57.77  ? 175 GLU A N   1 
ATOM   1117  C  CA  . GLU A 1 182 ? 145.137 177.070 140.619 1.00 57.77  ? 175 GLU A CA  1 
ATOM   1118  C  C   . GLU A 1 182 ? 144.907 175.566 140.665 1.00 57.77  ? 175 GLU A C   1 
ATOM   1119  O  O   . GLU A 1 182 ? 145.183 174.871 139.679 1.00 57.77  ? 175 GLU A O   1 
ATOM   1120  C  CB  . GLU A 1 182 ? 146.526 177.419 141.157 1.00 57.77  ? 175 GLU A CB  1 
ATOM   1121  C  CG  . GLU A 1 182 ? 147.212 178.605 140.471 1.00 57.77  ? 175 GLU A CG  1 
ATOM   1122  C  CD  . GLU A 1 182 ? 146.527 179.947 140.694 1.00 57.77  ? 175 GLU A CD  1 
ATOM   1123  O  OE1 . GLU A 1 182 ? 145.490 180.007 141.386 1.00 57.77  ? 175 GLU A OE1 1 
ATOM   1124  O  OE2 . GLU A 1 182 ? 147.037 180.959 140.168 1.00 57.77  ? 175 GLU A OE2 1 
ATOM   1125  N  N   . ASP A 1 183 ? 144.387 175.048 141.783 1.00 54.38  ? 176 ASP A N   1 
ATOM   1126  C  CA  . ASP A 1 183 ? 144.062 173.626 141.855 1.00 54.38  ? 176 ASP A CA  1 
ATOM   1127  C  C   . ASP A 1 183 ? 143.106 173.221 140.745 1.00 54.38  ? 176 ASP A C   1 
ATOM   1128  O  O   . ASP A 1 183 ? 143.160 172.086 140.258 1.00 54.38  ? 176 ASP A O   1 
ATOM   1129  C  CB  . ASP A 1 183 ? 143.456 173.289 143.215 1.00 54.38  ? 176 ASP A CB  1 
ATOM   1130  C  CG  . ASP A 1 183 ? 143.549 171.815 143.543 1.00 54.38  ? 176 ASP A CG  1 
ATOM   1131  O  OD1 . ASP A 1 183 ? 144.185 171.072 142.769 1.00 54.38  ? 176 ASP A OD1 1 
ATOM   1132  O  OD2 . ASP A 1 183 ? 142.980 171.397 144.572 1.00 54.38  ? 176 ASP A OD2 1 
ATOM   1133  N  N   . LEU A 1 184 ? 142.256 174.150 140.307 1.00 49.77  ? 177 LEU A N   1 
ATOM   1134  C  CA  . LEU A 1 184 ? 141.293 173.860 139.257 1.00 49.77  ? 177 LEU A CA  1 
ATOM   1135  C  C   . LEU A 1 184 ? 141.968 173.414 137.969 1.00 49.77  ? 177 LEU A C   1 
ATOM   1136  O  O   . LEU A 1 184 ? 141.324 172.770 137.135 1.00 49.77  ? 177 LEU A O   1 
ATOM   1137  C  CB  . LEU A 1 184 ? 140.437 175.097 138.996 1.00 49.77  ? 177 LEU A CB  1 
ATOM   1138  C  CG  . LEU A 1 184 ? 139.150 175.202 139.813 1.00 49.77  ? 177 LEU A CG  1 
ATOM   1139  C  CD1 . LEU A 1 184 ? 138.809 176.659 140.084 1.00 49.77  ? 177 LEU A CD1 1 
ATOM   1140  C  CD2 . LEU A 1 184 ? 138.006 174.503 139.115 1.00 49.77  ? 177 LEU A CD2 1 
ATOM   1141  N  N   . GLN A 1 185 ? 143.248 173.735 137.786 1.00 47.40  ? 178 GLN A N   1 
ATOM   1142  C  CA  . GLN A 1 185 ? 143.946 173.335 136.573 1.00 47.40  ? 178 GLN A CA  1 
ATOM   1143  C  C   . GLN A 1 185 ? 144.330 171.861 136.557 1.00 47.40  ? 178 GLN A C   1 
ATOM   1144  O  O   . GLN A 1 185 ? 144.685 171.349 135.491 1.00 47.40  ? 178 GLN A O   1 
ATOM   1145  C  CB  . GLN A 1 185 ? 145.201 174.187 136.378 1.00 47.40  ? 178 GLN A CB  1 
ATOM   1146  C  CG  . GLN A 1 185 ? 144.928 175.602 135.905 1.00 47.40  ? 178 GLN A CG  1 
ATOM   1147  C  CD  . GLN A 1 185 ? 146.193 176.425 135.789 1.00 47.40  ? 178 GLN A CD  1 
ATOM   1148  O  OE1 . GLN A 1 185 ? 147.300 175.895 135.875 1.00 47.40  ? 178 GLN A OE1 1 
ATOM   1149  N  NE2 . GLN A 1 185 ? 146.037 177.727 135.589 1.00 47.40  ? 178 GLN A NE2 1 
ATOM   1150  N  N   . ASP A 1 186 ? 144.270 171.167 137.692 1.00 46.02  ? 179 ASP A N   1 
ATOM   1151  C  CA  . ASP A 1 186 ? 144.632 169.756 137.742 1.00 46.02  ? 179 ASP A CA  1 
ATOM   1152  C  C   . ASP A 1 186 ? 143.430 168.834 137.607 1.00 46.02  ? 179 ASP A C   1 
ATOM   1153  O  O   . ASP A 1 186 ? 143.551 167.636 137.876 1.00 46.02  ? 179 ASP A O   1 
ATOM   1154  C  CB  . ASP A 1 186 ? 145.373 169.440 139.042 1.00 46.02  ? 179 ASP A CB  1 
ATOM   1155  C  CG  . ASP A 1 186 ? 146.593 170.309 139.243 1.00 46.02  ? 179 ASP A CG  1 
ATOM   1156  O  OD1 . ASP A 1 186 ? 147.393 170.443 138.296 1.00 46.02  ? 179 ASP A OD1 1 
ATOM   1157  O  OD2 . ASP A 1 186 ? 146.754 170.855 140.351 1.00 46.02  ? 179 ASP A OD2 1 
ATOM   1158  N  N   . MET A 1 187 ? 142.283 169.361 137.199 1.00 46.06  ? 180 MET A N   1 
ATOM   1159  C  CA  . MET A 1 187 ? 141.038 168.612 137.160 1.00 46.06  ? 180 MET A CA  1 
ATOM   1160  C  C   . MET A 1 187 ? 140.669 168.281 135.717 1.00 46.06  ? 180 MET A C   1 
ATOM   1161  O  O   . MET A 1 187 ? 141.432 168.523 134.781 1.00 46.06  ? 180 MET A O   1 
ATOM   1162  C  CB  . MET A 1 187 ? 139.927 169.421 137.831 1.00 46.06  ? 180 MET A CB  1 
ATOM   1163  C  CG  . MET A 1 187 ? 140.240 169.776 139.273 1.00 46.06  ? 180 MET A CG  1 
ATOM   1164  S  SD  . MET A 1 187 ? 138.792 170.061 140.298 1.00 46.06  ? 180 MET A SD  1 
ATOM   1165  C  CE  . MET A 1 187 ? 139.390 169.482 141.878 1.00 46.06  ? 180 MET A CE  1 
ATOM   1166  N  N   . SER A 1 188 ? 139.483 167.706 135.547 1.00 41.37  ? 181 SER A N   1 
ATOM   1167  C  CA  . SER A 1 188 ? 138.916 167.467 134.227 1.00 41.37  ? 181 SER A CA  1 
ATOM   1168  C  C   . SER A 1 188 ? 137.541 168.111 134.140 1.00 41.37  ? 181 SER A C   1 
ATOM   1169  O  O   . SER A 1 188 ? 136.744 168.020 135.078 1.00 41.37  ? 181 SER A O   1 
ATOM   1170  C  CB  . SER A 1 188 ? 138.816 165.971 133.927 1.00 41.37  ? 181 SER A CB  1 
ATOM   1171  O  OG  . SER A 1 188 ? 140.086 165.435 133.601 1.00 41.37  ? 181 SER A OG  1 
ATOM   1172  N  N   . LEU A 1 189 ? 137.269 168.764 133.017 1.00 40.42  ? 182 LEU A N   1 
ATOM   1173  C  CA  . LEU A 1 189 ? 136.011 169.469 132.835 1.00 40.42  ? 182 LEU A CA  1 
ATOM   1174  C  C   . LEU A 1 189 ? 134.942 168.538 132.285 1.00 40.42  ? 182 LEU A C   1 
ATOM   1175  O  O   . LEU A 1 189 ? 135.231 167.578 131.568 1.00 40.42  ? 182 LEU A O   1 
ATOM   1176  C  CB  . LEU A 1 189 ? 136.186 170.662 131.896 1.00 40.42  ? 182 LEU A CB  1 
ATOM   1177  C  CG  . LEU A 1 189 ? 136.925 171.870 132.469 1.00 40.42  ? 182 LEU A CG  1 
ATOM   1178  C  CD1 . LEU A 1 189 ? 138.383 171.861 132.041 1.00 40.42  ? 182 LEU A CD1 1 
ATOM   1179  C  CD2 . LEU A 1 189 ? 136.243 173.162 132.049 1.00 40.42  ? 182 LEU A CD2 1 
ATOM   1180  N  N   . MET A 1 190 ? 133.690 168.850 132.649 1.00 43.23  ? 183 MET A N   1 
ATOM   1181  C  CA  . MET A 1 190 ? 132.516 168.082 132.157 1.00 43.23  ? 183 MET A CA  1 
ATOM   1182  C  C   . MET A 1 190 ? 131.368 169.084 131.996 1.00 43.23  ? 183 MET A C   1 
ATOM   1183  O  O   . MET A 1 190 ? 131.107 169.832 132.961 1.00 43.23  ? 183 MET A O   1 
ATOM   1184  C  CB  . MET A 1 190 ? 132.109 166.985 133.146 1.00 43.23  ? 183 MET A CB  1 
ATOM   1185  C  CG  . MET A 1 190 ? 130.616 166.708 133.162 1.00 43.23  ? 183 MET A CG  1 
ATOM   1186  S  SD  . MET A 1 190 ? 130.180 165.317 134.233 1.00 43.23  ? 183 MET A SD  1 
ATOM   1187  C  CE  . MET A 1 190 ? 131.565 164.225 133.918 1.00 43.23  ? 183 MET A CE  1 
ATOM   1188  N  N   . THR A 1 191 ? 130.721 169.117 130.829 1.00 43.92  ? 184 THR A N   1 
ATOM   1189  C  CA  . THR A 1 191 ? 129.666 170.078 130.549 1.00 43.92  ? 184 THR A CA  1 
ATOM   1190  C  C   . THR A 1 191 ? 128.333 169.355 130.453 1.00 43.92  ? 184 THR A C   1 
ATOM   1191  O  O   . THR A 1 191 ? 128.203 168.383 129.703 1.00 43.92  ? 184 THR A O   1 
ATOM   1192  C  CB  . THR A 1 191 ? 129.948 170.843 129.253 1.00 43.92  ? 184 THR A CB  1 
ATOM   1193  O  OG1 . THR A 1 191 ? 131.029 171.760 129.463 1.00 43.92  ? 184 THR A OG1 1 
ATOM   1194  C  CG2 . THR A 1 191 ? 128.719 171.618 128.810 1.00 43.92  ? 184 THR A CG2 1 
ATOM   1195  N  N   . LEU A 1 192 ? 127.350 169.828 131.210 1.00 44.53  ? 185 LEU A N   1 
ATOM   1196  C  CA  . LEU A 1 192 ? 125.978 169.347 131.106 1.00 44.53  ? 185 LEU A CA  1 
ATOM   1197  C  C   . LEU A 1 192 ? 125.160 170.436 130.425 1.00 44.53  ? 185 LEU A C   1 
ATOM   1198  O  O   . LEU A 1 192 ? 124.890 171.480 131.026 1.00 44.53  ? 185 LEU A O   1 
ATOM   1199  C  CB  . LEU A 1 192 ? 125.404 169.001 132.477 1.00 44.53  ? 185 LEU A CB  1 
ATOM   1200  C  CG  . LEU A 1 192 ? 123.892 168.764 132.516 1.00 44.53  ? 185 LEU A CG  1 
ATOM   1201  C  CD1 . LEU A 1 192 ? 123.547 167.403 131.947 1.00 44.53  ? 185 LEU A CD1 1 
ATOM   1202  C  CD2 . LEU A 1 192 ? 123.361 168.899 133.929 1.00 44.53  ? 185 LEU A CD2 1 
ATOM   1203  N  N   . SER A 1 193 ? 124.787 170.202 129.172 1.00 49.25  ? 186 SER A N   1 
ATOM   1204  C  CA  . SER A 1 193 ? 123.994 171.148 128.401 1.00 49.25  ? 186 SER A CA  1 
ATOM   1205  C  C   . SER A 1 193 ? 122.540 170.703 128.433 1.00 49.25  ? 186 SER A C   1 
ATOM   1206  O  O   . SER A 1 193 ? 122.224 169.573 128.038 1.00 49.25  ? 186 SER A O   1 
ATOM   1207  C  CB  . SER A 1 193 ? 124.496 171.236 126.962 1.00 49.25  ? 186 SER A CB  1 
ATOM   1208  O  OG  . SER A 1 193 ? 125.789 171.811 126.912 1.00 49.25  ? 186 SER A OG  1 
ATOM   1209  N  N   . THR A 1 194 ? 121.661 171.585 128.907 1.00 54.56  ? 187 THR A N   1 
ATOM   1210  C  CA  . THR A 1 194 ? 120.238 171.303 129.007 1.00 54.56  ? 187 THR A CA  1 
ATOM   1211  C  C   . THR A 1 194 ? 119.469 172.332 128.196 1.00 54.56  ? 187 THR A C   1 
ATOM   1212  O  O   . THR A 1 194 ? 119.723 173.536 128.308 1.00 54.56  ? 187 THR A O   1 
ATOM   1213  C  CB  . THR A 1 194 ? 119.771 171.327 130.462 1.00 54.56  ? 187 THR A CB  1 
ATOM   1214  O  OG1 . THR A 1 194 ? 120.110 172.588 131.050 1.00 54.56  ? 187 THR A OG1 1 
ATOM   1215  C  CG2 . THR A 1 194 ? 120.441 170.216 131.249 1.00 54.56  ? 187 THR A CG2 1 
ATOM   1216  N  N   . LYS A 1 195 ? 118.536 171.856 127.378 1.00 57.89  ? 188 LYS A N   1 
ATOM   1217  C  CA  . LYS A 1 195 ? 117.674 172.727 126.580 1.00 57.89  ? 188 LYS A CA  1 
ATOM   1218  C  C   . LYS A 1 195 ? 116.271 172.137 126.654 1.00 57.89  ? 188 LYS A C   1 
ATOM   1219  O  O   . LYS A 1 195 ? 115.965 171.159 125.966 1.00 57.89  ? 188 LYS A O   1 
ATOM   1220  C  CB  . LYS A 1 195 ? 118.168 172.839 125.144 1.00 57.89  ? 188 LYS A CB  1 
ATOM   1221  C  CG  . LYS A 1 195 ? 117.422 173.860 124.309 1.00 57.89  ? 188 LYS A CG  1 
ATOM   1222  C  CD  . LYS A 1 195 ? 118.270 174.326 123.138 1.00 57.89  ? 188 LYS A CD  1 
ATOM   1223  C  CE  . LYS A 1 195 ? 117.484 175.236 122.211 1.00 57.89  ? 188 LYS A CE  1 
ATOM   1224  N  NZ  . LYS A 1 195 ? 116.704 176.257 122.961 1.00 57.89  ? 188 LYS A NZ  1 
ATOM   1225  N  N   . THR A 1 196 ? 115.443 172.707 127.519 1.00 62.47  ? 189 THR A N   1 
ATOM   1226  C  CA  . THR A 1 196 ? 114.109 172.208 127.808 1.00 62.47  ? 189 THR A CA  1 
ATOM   1227  C  C   . THR A 1 196 ? 113.148 173.383 127.873 1.00 62.47  ? 189 THR A C   1 
ATOM   1228  O  O   . THR A 1 196 ? 113.577 174.535 128.000 1.00 62.47  ? 189 THR A O   1 
ATOM   1229  C  CB  . THR A 1 196 ? 114.057 171.434 129.134 1.00 62.47  ? 189 THR A CB  1 
ATOM   1230  O  OG1 . THR A 1 196 ? 113.785 172.344 130.207 1.00 62.47  ? 189 THR A OG1 1 
ATOM   1231  C  CG2 . THR A 1 196 ? 115.367 170.711 129.408 1.00 62.47  ? 189 THR A CG2 1 
ATOM   1232  N  N   . PRO A 1 197 ? 111.844 173.130 127.773 1.00 65.91  ? 190 PRO A N   1 
ATOM   1233  C  CA  . PRO A 1 197 ? 110.864 174.203 127.988 1.00 65.91  ? 190 PRO A CA  1 
ATOM   1234  C  C   . PRO A 1 197 ? 110.962 174.787 129.391 1.00 65.91  ? 190 PRO A C   1 
ATOM   1235  O  O   . PRO A 1 197 ? 111.665 174.285 130.270 1.00 65.91  ? 190 PRO A O   1 
ATOM   1236  C  CB  . PRO A 1 197 ? 109.521 173.506 127.760 1.00 65.91  ? 190 PRO A CB  1 
ATOM   1237  C  CG  . PRO A 1 197 ? 109.841 172.392 126.834 1.00 65.91  ? 190 PRO A CG  1 
ATOM   1238  C  CD  . PRO A 1 197 ? 111.212 171.918 127.222 1.00 65.91  ? 190 PRO A CD  1 
ATOM   1239  N  N   . LYS A 1 198 ? 110.227 175.885 129.593 1.00 66.56  ? 191 LYS A N   1 
ATOM   1240  C  CA  . LYS A 1 198 ? 110.324 176.635 130.842 1.00 66.56  ? 191 LYS A CA  1 
ATOM   1241  C  C   . LYS A 1 198 ? 109.800 175.834 132.028 1.00 66.56  ? 191 LYS A C   1 
ATOM   1242  O  O   . LYS A 1 198 ? 110.428 175.809 133.092 1.00 66.56  ? 191 LYS A O   1 
ATOM   1243  C  CB  . LYS A 1 198 ? 109.563 177.958 130.717 1.00 66.56  ? 191 LYS A CB  1 
ATOM   1244  C  CG  . LYS A 1 198 ? 109.820 178.739 129.424 1.00 66.56  ? 191 LYS A CG  1 
ATOM   1245  C  CD  . LYS A 1 198 ? 111.290 179.102 129.179 1.00 66.56  ? 191 LYS A CD  1 
ATOM   1246  C  CE  . LYS A 1 198 ? 112.029 179.522 130.449 1.00 66.56  ? 191 LYS A CE  1 
ATOM   1247  N  NZ  . LYS A 1 198 ? 111.369 180.673 131.125 1.00 66.56  ? 191 LYS A NZ  1 
ATOM   1248  N  N   . ASP A 1 199 ? 108.652 175.177 131.868 1.00 66.75  ? 192 ASP A N   1 
ATOM   1249  C  CA  . ASP A 1 199 ? 108.009 174.441 132.948 1.00 66.75  ? 192 ASP A CA  1 
ATOM   1250  C  C   . ASP A 1 199 ? 108.354 172.953 132.945 1.00 66.75  ? 192 ASP A C   1 
ATOM   1251  O  O   . ASP A 1 199 ? 107.670 172.164 133.606 1.00 66.75  ? 192 ASP A O   1 
ATOM   1252  C  CB  . ASP A 1 199 ? 106.492 174.697 132.914 1.00 66.75  ? 192 ASP A CB  1 
ATOM   1253  C  CG  . ASP A 1 199 ? 105.705 173.744 131.990 1.00 66.75  ? 192 ASP A CG  1 
ATOM   1254  O  OD1 . ASP A 1 199 ? 104.482 173.964 131.858 1.00 66.75  ? 192 ASP A OD1 1 
ATOM   1255  O  OD2 . ASP A 1 199 ? 106.266 172.842 131.335 1.00 66.75  ? 192 ASP A OD2 1 
ATOM   1256  N  N   . PHE A 1 200 ? 109.413 172.563 132.234 1.00 60.86  ? 193 PHE A N   1 
ATOM   1257  C  CA  . PHE A 1 200 ? 109.737 171.146 132.093 1.00 60.86  ? 193 PHE A CA  1 
ATOM   1258  C  C   . PHE A 1 200 ? 110.083 170.509 133.432 1.00 60.86  ? 193 PHE A C   1 
ATOM   1259  O  O   . PHE A 1 200 ? 109.533 169.462 133.791 1.00 60.86  ? 193 PHE A O   1 
ATOM   1260  C  CB  . PHE A 1 200 ? 110.890 170.969 131.107 1.00 60.86  ? 193 PHE A CB  1 
ATOM   1261  C  CG  . PHE A 1 200 ? 111.313 169.541 130.925 1.00 60.86  ? 193 PHE A CG  1 
ATOM   1262  C  CD1 . PHE A 1 200 ? 110.478 168.632 130.304 1.00 60.86  ? 193 PHE A CD1 1 
ATOM   1263  C  CD2 . PHE A 1 200 ? 112.548 169.110 131.376 1.00 60.86  ? 193 PHE A CD2 1 
ATOM   1264  C  CE1 . PHE A 1 200 ? 110.866 167.320 130.137 1.00 60.86  ? 193 PHE A CE1 1 
ATOM   1265  C  CE2 . PHE A 1 200 ? 112.942 167.800 131.209 1.00 60.86  ? 193 PHE A CE2 1 
ATOM   1266  C  CZ  . PHE A 1 200 ? 112.101 166.903 130.591 1.00 60.86  ? 193 PHE A CZ  1 
ATOM   1267  N  N   . PHE A 1 201 ? 110.983 171.128 134.192 1.00 57.07  ? 194 PHE A N   1 
ATOM   1268  C  CA  . PHE A 1 201 ? 111.545 170.479 135.369 1.00 57.07  ? 194 PHE A CA  1 
ATOM   1269  C  C   . PHE A 1 201 ? 110.637 170.545 136.587 1.00 57.07  ? 194 PHE A C   1 
ATOM   1270  O  O   . PHE A 1 201 ? 111.058 170.143 137.677 1.00 57.07  ? 194 PHE A O   1 
ATOM   1271  C  CB  . PHE A 1 201 ? 112.914 171.077 135.691 1.00 57.07  ? 194 PHE A CB  1 
ATOM   1272  C  CG  . PHE A 1 201 ? 114.018 170.495 134.866 1.00 57.07  ? 194 PHE A CG  1 
ATOM   1273  C  CD1 . PHE A 1 201 ? 114.625 169.313 135.237 1.00 57.07  ? 194 PHE A CD1 1 
ATOM   1274  C  CD2 . PHE A 1 201 ? 114.431 171.118 133.704 1.00 57.07  ? 194 PHE A CD2 1 
ATOM   1275  C  CE1 . PHE A 1 201 ? 115.629 168.769 134.470 1.00 57.07  ? 194 PHE A CE1 1 
ATOM   1276  C  CE2 . PHE A 1 201 ? 115.439 170.580 132.936 1.00 57.07  ? 194 PHE A CE2 1 
ATOM   1277  C  CZ  . PHE A 1 201 ? 116.037 169.405 133.319 1.00 57.07  ? 194 PHE A CZ  1 
ATOM   1278  N  N   . THR A 1 202 ? 109.408 171.037 136.434 1.00 62.60  ? 195 THR A N   1 
ATOM   1279  C  CA  . THR A 1 202 ? 108.426 170.895 137.499 1.00 62.60  ? 195 THR A CA  1 
ATOM   1280  C  C   . THR A 1 202 ? 107.933 169.458 137.618 1.00 62.60  ? 195 THR A C   1 
ATOM   1281  O  O   . THR A 1 202 ? 107.462 169.061 138.689 1.00 62.60  ? 195 THR A O   1 
ATOM   1282  C  CB  . THR A 1 202 ? 107.248 171.844 137.257 1.00 62.60  ? 195 THR A CB  1 
ATOM   1283  O  OG1 . THR A 1 202 ? 107.744 173.131 136.872 1.00 62.60  ? 195 THR A OG1 1 
ATOM   1284  C  CG2 . THR A 1 202 ? 106.413 172.000 138.519 1.00 62.60  ? 195 THR A CG2 1 
ATOM   1285  N  N   . ASN A 1 203 ? 108.048 168.666 136.548 1.00 59.89  ? 196 ASN A N   1 
ATOM   1286  C  CA  . ASN A 1 203 ? 107.596 167.279 136.553 1.00 59.89  ? 196 ASN A CA  1 
ATOM   1287  C  C   . ASN A 1 203 ? 108.698 166.311 136.134 1.00 59.89  ? 196 ASN A C   1 
ATOM   1288  O  O   . ASN A 1 203 ? 108.397 165.215 135.653 1.00 59.89  ? 196 ASN A O   1 
ATOM   1289  C  CB  . ASN A 1 203 ? 106.377 167.107 135.645 1.00 59.89  ? 196 ASN A CB  1 
ATOM   1290  C  CG  . ASN A 1 203 ? 105.189 167.923 136.108 1.00 59.89  ? 196 ASN A CG  1 
ATOM   1291  O  OD1 . ASN A 1 203 ? 104.750 167.807 137.252 1.00 59.89  ? 196 ASN A OD1 1 
ATOM   1292  N  ND2 . ASN A 1 203 ? 104.658 168.753 135.218 1.00 59.89  ? 196 ASN A ND2 1 
ATOM   1293  N  N   . HIS A 1 204 ? 109.963 166.689 136.303 1.00 52.86  ? 197 HIS A N   1 
ATOM   1294  C  CA  . HIS A 1 204 ? 111.082 165.820 135.970 1.00 52.86  ? 197 HIS A CA  1 
ATOM   1295  C  C   . HIS A 1 204 ? 112.270 166.194 136.843 1.00 52.86  ? 197 HIS A C   1 
ATOM   1296  O  O   . HIS A 1 204 ? 112.340 167.299 137.387 1.00 52.86  ? 197 HIS A O   1 
ATOM   1297  C  CB  . HIS A 1 204 ? 111.451 165.914 134.485 1.00 52.86  ? 197 HIS A CB  1 
ATOM   1298  C  CG  . HIS A 1 204 ? 110.495 165.204 133.579 1.00 52.86  ? 197 HIS A CG  1 
ATOM   1299  N  ND1 . HIS A 1 204 ? 109.612 165.871 132.758 1.00 52.86  ? 197 HIS A ND1 1 
ATOM   1300  C  CD2 . HIS A 1 204 ? 110.282 163.884 133.367 1.00 52.86  ? 197 HIS A CD2 1 
ATOM   1301  C  CE1 . HIS A 1 204 ? 108.897 164.993 132.078 1.00 52.86  ? 197 HIS A CE1 1 
ATOM   1302  N  NE2 . HIS A 1 204 ? 109.284 163.780 132.429 1.00 52.86  ? 197 HIS A NE2 1 
ATOM   1303  N  N   . THR A 1 205 ? 113.206 165.258 136.975 1.00 44.47  ? 198 THR A N   1 
ATOM   1304  C  CA  . THR A 1 205 ? 114.365 165.437 137.837 1.00 44.47  ? 198 THR A CA  1 
ATOM   1305  C  C   . THR A 1 205 ? 115.598 164.877 137.143 1.00 44.47  ? 198 THR A C   1 
ATOM   1306  O  O   . THR A 1 205 ? 115.508 163.928 136.364 1.00 44.47  ? 198 THR A O   1 
ATOM   1307  C  CB  . THR A 1 205 ? 114.131 164.752 139.203 1.00 44.47  ? 198 THR A CB  1 
ATOM   1308  O  OG1 . THR A 1 205 ? 113.250 165.557 139.994 1.00 44.47  ? 198 THR A OG1 1 
ATOM   1309  C  CG2 . THR A 1 205 ? 115.428 164.553 139.970 1.00 44.47  ? 198 THR A CG2 1 
ATOM   1310  N  N   . LEU A 1 206 ? 116.752 165.483 137.413 1.00 38.84  ? 199 LEU A N   1 
ATOM   1311  C  CA  . LEU A 1 206 ? 118.024 165.014 136.886 1.00 38.84  ? 199 LEU A CA  1 
ATOM   1312  C  C   . LEU A 1 206 ? 118.865 164.489 138.042 1.00 38.84  ? 199 LEU A C   1 
ATOM   1313  O  O   . LEU A 1 206 ? 118.807 165.028 139.151 1.00 38.84  ? 199 LEU A O   1 
ATOM   1314  C  CB  . LEU A 1 206 ? 118.770 166.134 136.161 1.00 38.84  ? 199 LEU A CB  1 
ATOM   1315  C  CG  . LEU A 1 206 ? 118.461 166.319 134.672 1.00 38.84  ? 199 LEU A CG  1 
ATOM   1316  C  CD1 . LEU A 1 206 ? 118.938 167.681 134.193 1.00 38.84  ? 199 LEU A CD1 1 
ATOM   1317  C  CD2 . LEU A 1 206 ? 119.033 165.210 133.818 1.00 38.84  ? 199 LEU A CD2 1 
ATOM   1318  N  N   . VAL A 1 207 ? 119.629 163.428 137.794 1.00 33.92  ? 200 VAL A N   1 
ATOM   1319  C  CA  . VAL A 1 207 ? 120.475 162.810 138.809 1.00 33.92  ? 200 VAL A CA  1 
ATOM   1320  C  C   . VAL A 1 207 ? 121.848 162.550 138.212 1.00 33.92  ? 200 VAL A C   1 
ATOM   1321  O  O   . VAL A 1 207 ? 121.962 162.154 137.048 1.00 33.92  ? 200 VAL A O   1 
ATOM   1322  C  CB  . VAL A 1 207 ? 119.873 161.492 139.337 1.00 33.92  ? 200 VAL A CB  1 
ATOM   1323  C  CG1 . VAL A 1 207 ? 120.695 160.960 140.495 1.00 33.92  ? 200 VAL A CG1 1 
ATOM   1324  C  CG2 . VAL A 1 207 ? 118.441 161.694 139.756 1.00 33.92  ? 200 VAL A CG2 1 
ATOM   1325  N  N   . LEU A 1 208 ? 122.889 162.765 139.008 1.00 30.47  ? 201 LEU A N   1 
ATOM   1326  C  CA  . LEU A 1 208 ? 124.246 162.403 138.634 1.00 30.47  ? 201 LEU A CA  1 
ATOM   1327  C  C   . LEU A 1 208 ? 124.728 161.331 139.595 1.00 30.47  ? 201 LEU A C   1 
ATOM   1328  O  O   . LEU A 1 208 ? 124.461 161.410 140.799 1.00 30.47  ? 201 LEU A O   1 
ATOM   1329  C  CB  . LEU A 1 208 ? 125.176 163.616 138.680 1.00 30.47  ? 201 LEU A CB  1 
ATOM   1330  C  CG  . LEU A 1 208 ? 126.540 163.467 138.015 1.00 30.47  ? 201 LEU A CG  1 
ATOM   1331  C  CD1 . LEU A 1 208 ? 126.400 163.579 136.512 1.00 30.47  ? 201 LEU A CD1 1 
ATOM   1332  C  CD2 . LEU A 1 208 ? 127.500 164.513 138.540 1.00 30.47  ? 201 LEU A CD2 1 
ATOM   1333  N  N   . HIS A 1 209 ? 125.416 160.317 139.077 1.00 28.76  ? 202 HIS A N   1 
ATOM   1334  C  CA  . HIS A 1 209 ? 125.847 159.245 139.966 1.00 28.76  ? 202 HIS A CA  1 
ATOM   1335  C  C   . HIS A 1 209 ? 127.047 158.509 139.387 1.00 28.76  ? 202 HIS A C   1 
ATOM   1336  O  O   . HIS A 1 209 ? 127.422 158.682 138.225 1.00 28.76  ? 202 HIS A O   1 
ATOM   1337  C  CB  . HIS A 1 209 ? 124.699 158.274 140.266 1.00 28.76  ? 202 HIS A CB  1 
ATOM   1338  C  CG  . HIS A 1 209 ? 124.193 157.531 139.071 1.00 28.76  ? 202 HIS A CG  1 
ATOM   1339  N  ND1 . HIS A 1 209 ? 123.041 157.890 138.405 1.00 28.76  ? 202 HIS A ND1 1 
ATOM   1340  C  CD2 . HIS A 1 209 ? 124.661 156.427 138.443 1.00 28.76  ? 202 HIS A CD2 1 
ATOM   1341  C  CE1 . HIS A 1 209 ? 122.833 157.052 137.406 1.00 28.76  ? 202 HIS A CE1 1 
ATOM   1342  N  NE2 . HIS A 1 209 ? 123.799 156.153 137.410 1.00 28.76  ? 202 HIS A NE2 1 
ATOM   1343  N  N   . VAL A 1 210 ? 127.661 157.702 140.250 1.00 29.58  ? 203 VAL A N   1 
ATOM   1344  C  CA  . VAL A 1 210 ? 128.769 156.821 139.913 1.00 29.58  ? 203 VAL A CA  1 
ATOM   1345  C  C   . VAL A 1 210 ? 128.541 155.506 140.646 1.00 29.58  ? 203 VAL A C   1 
ATOM   1346  O  O   . VAL A 1 210 ? 127.980 155.480 141.745 1.00 29.58  ? 203 VAL A O   1 
ATOM   1347  C  CB  . VAL A 1 210 ? 130.130 157.450 140.289 1.00 29.58  ? 203 VAL A CB  1 
ATOM   1348  C  CG1 . VAL A 1 210 ? 130.205 157.696 141.781 1.00 29.58  ? 203 VAL A CG1 1 
ATOM   1349  C  CG2 . VAL A 1 210 ? 131.279 156.567 139.845 1.00 29.58  ? 203 VAL A CG2 1 
ATOM   1350  N  N   . ALA A 1 211 ? 128.961 154.405 140.026 1.00 33.15  ? 204 ALA A N   1 
ATOM   1351  C  CA  . ALA A 1 211 ? 128.731 153.090 140.610 1.00 33.15  ? 204 ALA A CA  1 
ATOM   1352  C  C   . ALA A 1 211 ? 129.415 152.976 141.967 1.00 33.15  ? 204 ALA A C   1 
ATOM   1353  O  O   . ALA A 1 211 ? 130.461 153.579 142.210 1.00 33.15  ? 204 ALA A O   1 
ATOM   1354  C  CB  . ALA A 1 211 ? 129.238 151.996 139.672 1.00 33.15  ? 204 ALA A CB  1 
ATOM   1355  N  N   . ARG A 1 212 ? 128.807 152.188 142.860 1.00 30.95  ? 205 ARG A N   1 
ATOM   1356  C  CA  . ARG A 1 212 ? 129.285 152.101 144.236 1.00 30.95  ? 205 ARG A CA  1 
ATOM   1357  C  C   . ARG A 1 212 ? 130.699 151.546 144.342 1.00 30.95  ? 205 ARG A C   1 
ATOM   1358  O  O   . ARG A 1 212 ? 131.374 151.796 145.345 1.00 30.95  ? 205 ARG A O   1 
ATOM   1359  C  CB  . ARG A 1 212 ? 128.340 151.239 145.070 1.00 30.95  ? 205 ARG A CB  1 
ATOM   1360  C  CG  . ARG A 1 212 ? 127.070 151.942 145.497 1.00 30.95  ? 205 ARG A CG  1 
ATOM   1361  C  CD  . ARG A 1 212 ? 126.491 151.307 146.748 1.00 30.95  ? 205 ARG A CD  1 
ATOM   1362  N  NE  . ARG A 1 212 ? 125.430 152.118 147.330 1.00 30.95  ? 205 ARG A NE  1 
ATOM   1363  C  CZ  . ARG A 1 212 ? 125.531 152.762 148.484 1.00 30.95  ? 205 ARG A CZ  1 
ATOM   1364  N  NH1 . ARG A 1 212 ? 126.636 152.710 149.209 1.00 30.95  ? 205 ARG A NH1 1 
ATOM   1365  N  NH2 . ARG A 1 212 ? 124.498 153.478 148.920 1.00 30.95  ? 205 ARG A NH2 1 
ATOM   1366  N  N   . SER A 1 213 ? 131.161 150.791 143.345 1.00 32.56  ? 206 SER A N   1 
ATOM   1367  C  CA  . SER A 1 213 ? 132.517 150.262 143.398 1.00 32.56  ? 206 SER A CA  1 
ATOM   1368  C  C   . SER A 1 213 ? 133.555 151.293 142.983 1.00 32.56  ? 206 SER A C   1 
ATOM   1369  O  O   . SER A 1 213 ? 134.748 151.085 143.225 1.00 32.56  ? 206 SER A O   1 
ATOM   1370  C  CB  . SER A 1 213 ? 132.640 149.026 142.510 1.00 32.56  ? 206 SER A CB  1 
ATOM   1371  O  OG  . SER A 1 213 ? 133.971 148.865 142.055 1.00 32.56  ? 206 SER A OG  1 
ATOM   1372  N  N   . GLU A 1 214 ? 133.132 152.391 142.361 1.00 34.01  ? 207 GLU A N   1 
ATOM   1373  C  CA  . GLU A 1 214 ? 134.030 153.458 141.941 1.00 34.01  ? 207 GLU A CA  1 
ATOM   1374  C  C   . GLU A 1 214 ? 133.736 154.772 142.649 1.00 34.01  ? 207 GLU A C   1 
ATOM   1375  O  O   . GLU A 1 214 ? 134.420 155.768 142.400 1.00 34.01  ? 207 GLU A O   1 
ATOM   1376  C  CB  . GLU A 1 214 ? 133.950 153.647 140.425 1.00 34.01  ? 207 GLU A CB  1 
ATOM   1377  C  CG  . GLU A 1 214 ? 134.492 152.471 139.629 1.00 34.01  ? 207 GLU A CG  1 
ATOM   1378  C  CD  . GLU A 1 214 ? 133.573 152.056 138.497 1.00 34.01  ? 207 GLU A CD  1 
ATOM   1379  O  OE1 . GLU A 1 214 ? 132.498 152.670 138.344 1.00 34.01  ? 207 GLU A OE1 1 
ATOM   1380  O  OE2 . GLU A 1 214 ? 133.928 151.113 137.758 1.00 34.01  ? 207 GLU A OE2 1 
ATOM   1381  N  N   . MET A 1 215 ? 132.729 154.798 143.524 1.00 35.59  ? 208 MET A N   1 
ATOM   1382  C  CA  . MET A 1 215 ? 132.388 156.017 144.246 1.00 35.59  ? 208 MET A CA  1 
ATOM   1383  C  C   . MET A 1 215 ? 133.494 156.459 145.188 1.00 35.59  ? 208 MET A C   1 
ATOM   1384  O  O   . MET A 1 215 ? 133.519 157.626 145.591 1.00 35.59  ? 208 MET A O   1 
ATOM   1385  C  CB  . MET A 1 215 ? 131.090 155.811 145.028 1.00 35.59  ? 208 MET A CB  1 
ATOM   1386  C  CG  . MET A 1 215 ? 131.293 155.564 146.511 1.00 35.59  ? 208 MET A CG  1 
ATOM   1387  S  SD  . MET A 1 215 ? 129.758 155.603 147.445 1.00 35.59  ? 208 MET A SD  1 
ATOM   1388  C  CE  . MET A 1 215 ? 130.268 154.799 148.960 1.00 35.59  ? 208 MET A CE  1 
ATOM   1389  N  N   . ASP A 1 216 ? 134.408 155.562 145.548 1.00 36.33  ? 209 ASP A N   1 
ATOM   1390  C  CA  . ASP A 1 216 ? 135.489 155.878 146.467 1.00 36.33  ? 209 ASP A CA  1 
ATOM   1391  C  C   . ASP A 1 216 ? 136.811 156.153 145.754 1.00 36.33  ? 209 ASP A C   1 
ATOM   1392  O  O   . ASP A 1 216 ? 137.856 156.236 146.408 1.00 36.33  ? 209 ASP A O   1 
ATOM   1393  C  CB  . ASP A 1 216 ? 135.598 154.773 147.531 1.00 36.33  ? 209 ASP A CB  1 
ATOM   1394  C  CG  . ASP A 1 216 ? 136.325 153.511 147.052 1.00 36.33  ? 209 ASP A CG  1 
ATOM   1395  O  OD1 . ASP A 1 216 ? 135.853 152.414 147.418 1.00 36.33  ? 209 ASP A OD1 1 
ATOM   1396  O  OD2 . ASP A 1 216 ? 137.351 153.571 146.351 1.00 36.33  ? 209 ASP A OD2 1 
ATOM   1397  N  N   . LYS A 1 217 ? 136.780 156.327 144.428 1.00 33.44  ? 210 LYS A N   1 
ATOM   1398  C  CA  . LYS A 1 217 ? 137.975 156.654 143.657 1.00 33.44  ? 210 LYS A CA  1 
ATOM   1399  C  C   . LYS A 1 217 ? 137.764 157.863 142.751 1.00 33.44  ? 210 LYS A C   1 
ATOM   1400  O  O   . LYS A 1 217 ? 138.474 158.005 141.752 1.00 33.44  ? 210 LYS A O   1 
ATOM   1401  C  CB  . LYS A 1 217 ? 138.429 155.458 142.817 1.00 33.44  ? 210 LYS A CB  1 
ATOM   1402  C  CG  . LYS A 1 217 ? 138.721 154.199 143.608 1.00 33.44  ? 210 LYS A CG  1 
ATOM   1403  C  CD  . LYS A 1 217 ? 138.903 153.005 142.688 1.00 33.44  ? 210 LYS A CD  1 
ATOM   1404  C  CE  . LYS A 1 217 ? 139.163 151.730 143.472 1.00 33.44  ? 210 LYS A CE  1 
ATOM   1405  N  NZ  . LYS A 1 217 ? 137.943 151.240 144.166 1.00 33.44  ? 210 LYS A NZ  1 
ATOM   1406  N  N   . VAL A 1 218 ? 136.809 158.735 143.069 1.00 31.45  ? 211 VAL A N   1 
ATOM   1407  C  CA  . VAL A 1 218 ? 136.522 159.895 142.234 1.00 31.45  ? 211 VAL A CA  1 
ATOM   1408  C  C   . VAL A 1 218 ? 135.823 160.947 143.083 1.00 31.45  ? 211 VAL A C   1 
ATOM   1409  O  O   . VAL A 1 218 ? 135.172 160.630 144.082 1.00 31.45  ? 211 VAL A O   1 
ATOM   1410  C  CB  . VAL A 1 218 ? 135.666 159.507 141.004 1.00 31.45  ? 211 VAL A CB  1 
ATOM   1411  C  CG1 . VAL A 1 218 ? 134.214 159.312 141.396 1.00 31.45  ? 211 VAL A CG1 1 
ATOM   1412  C  CG2 . VAL A 1 218 ? 135.794 160.547 139.913 1.00 31.45  ? 211 VAL A CG2 1 
ATOM   1413  N  N   . ARG A 1 219 ? 135.980 162.211 142.693 1.00 39.79  ? 212 ARG A N   1 
ATOM   1414  C  CA  . ARG A 1 219 ? 135.258 163.306 143.324 1.00 39.79  ? 212 ARG A CA  1 
ATOM   1415  C  C   . ARG A 1 219 ? 134.884 164.330 142.266 1.00 39.79  ? 212 ARG A C   1 
ATOM   1416  O  O   . ARG A 1 219 ? 135.685 164.646 141.381 1.00 39.79  ? 212 ARG A O   1 
ATOM   1417  C  CB  . ARG A 1 219 ? 136.078 163.968 144.436 1.00 39.79  ? 212 ARG A CB  1 
ATOM   1418  C  CG  . ARG A 1 219 ? 135.288 164.978 145.255 1.00 39.79  ? 212 ARG A CG  1 
ATOM   1419  C  CD  . ARG A 1 219 ? 136.109 165.539 146.401 1.00 39.79  ? 212 ARG A CD  1 
ATOM   1420  N  NE  . ARG A 1 219 ? 136.121 164.654 147.558 1.00 39.79  ? 212 ARG A NE  1 
ATOM   1421  C  CZ  . ARG A 1 219 ? 137.212 164.087 148.054 1.00 39.79  ? 212 ARG A CZ  1 
ATOM   1422  N  NH1 . ARG A 1 219 ? 138.401 164.281 147.508 1.00 39.79  ? 212 ARG A NH1 1 
ATOM   1423  N  NH2 . ARG A 1 219 ? 137.107 163.306 149.125 1.00 39.79  ? 212 ARG A NH2 1 
ATOM   1424  N  N   . VAL A 1 220 ? 133.660 164.843 142.366 1.00 36.17  ? 213 VAL A N   1 
ATOM   1425  C  CA  . VAL A 1 220 ? 133.082 165.736 141.369 1.00 36.17  ? 213 VAL A CA  1 
ATOM   1426  C  C   . VAL A 1 220 ? 132.494 166.946 142.078 1.00 36.17  ? 213 VAL A C   1 
ATOM   1427  O  O   . VAL A 1 220 ? 131.613 166.795 142.936 1.00 36.17  ? 213 VAL A O   1 
ATOM   1428  C  CB  . VAL A 1 220 ? 132.004 165.036 140.528 1.00 36.17  ? 213 VAL A CB  1 
ATOM   1429  C  CG1 . VAL A 1 220 ? 131.266 166.045 139.674 1.00 36.17  ? 213 VAL A CG1 1 
ATOM   1430  C  CG2 . VAL A 1 220 ? 132.636 163.974 139.659 1.00 36.17  ? 213 VAL A CG2 1 
ATOM   1431  N  N   . PHE A 1 221 ? 132.969 168.135 141.702 1.00 41.61  ? 214 PHE A N   1 
ATOM   1432  C  CA  . PHE A 1 221 ? 132.487 169.420 142.186 1.00 41.61  ? 214 PHE A CA  1 
ATOM   1433  C  C   . PHE A 1 221 ? 131.633 170.100 141.123 1.00 41.61  ? 214 PHE A C   1 
ATOM   1434  O  O   . PHE A 1 221 ? 131.823 169.889 139.923 1.00 41.61  ? 214 PHE A O   1 
ATOM   1435  C  CB  . PHE A 1 221 ? 133.641 170.365 142.536 1.00 41.61  ? 214 PHE A CB  1 
ATOM   1436  C  CG  . PHE A 1 221 ? 134.642 169.796 143.492 1.00 41.61  ? 214 PHE A CG  1 
ATOM   1437  C  CD1 . PHE A 1 221 ? 135.750 169.114 143.029 1.00 41.61  ? 214 PHE A CD1 1 
ATOM   1438  C  CD2 . PHE A 1 221 ? 134.497 169.978 144.854 1.00 41.61  ? 214 PHE A CD2 1 
ATOM   1439  C  CE1 . PHE A 1 221 ? 136.679 168.605 143.906 1.00 41.61  ? 214 PHE A CE1 1 
ATOM   1440  C  CE2 . PHE A 1 221 ? 135.425 169.471 145.735 1.00 41.61  ? 214 PHE A CE2 1 
ATOM   1441  C  CZ  . PHE A 1 221 ? 136.517 168.785 145.260 1.00 41.61  ? 214 PHE A CZ  1 
ATOM   1442  N  N   . GLN A 1 222 ? 130.716 170.949 141.579 1.00 44.79  ? 215 GLN A N   1 
ATOM   1443  C  CA  . GLN A 1 222 ? 129.881 171.773 140.714 1.00 44.79  ? 215 GLN A CA  1 
ATOM   1444  C  C   . GLN A 1 222 ? 130.384 173.210 140.743 1.00 44.79  ? 215 GLN A C   1 
ATOM   1445  O  O   . GLN A 1 222 ? 130.548 173.788 141.821 1.00 44.79  ? 215 GLN A O   1 
ATOM   1446  C  CB  . GLN A 1 222 ? 128.424 171.724 141.171 1.00 44.79  ? 215 GLN A CB  1 
ATOM   1447  C  CG  . GLN A 1 222 ? 127.492 172.669 140.449 1.00 44.79  ? 215 GLN A CG  1 
ATOM   1448  C  CD  . GLN A 1 222 ? 126.108 172.679 141.067 1.00 44.79  ? 215 GLN A CD  1 
ATOM   1449  O  OE1 . GLN A 1 222 ? 125.846 171.970 142.038 1.00 44.79  ? 215 GLN A OE1 1 
ATOM   1450  N  NE2 . GLN A 1 222 ? 125.223 173.507 140.528 1.00 44.79  ? 215 GLN A NE2 1 
ATOM   1451  N  N   . ALA A 1 223 ? 130.616 173.788 139.567 1.00 51.85  ? 216 ALA A N   1 
ATOM   1452  C  CA  . ALA A 1 223 ? 131.124 175.149 139.472 1.00 51.85  ? 216 ALA A CA  1 
ATOM   1453  C  C   . ALA A 1 223 ? 129.974 176.122 139.257 1.00 51.85  ? 216 ALA A C   1 
ATOM   1454  O  O   . ALA A 1 223 ? 129.110 175.895 138.404 1.00 51.85  ? 216 ALA A O   1 
ATOM   1455  C  CB  . ALA A 1 223 ? 132.134 175.268 138.333 1.00 51.85  ? 216 ALA A CB  1 
ATOM   1456  N  N   . THR A 1 224 ? 129.968 177.203 140.028 1.00 62.91  ? 217 THR A N   1 
ATOM   1457  C  CA  . THR A 1 224 ? 128.936 178.225 139.904 1.00 62.91  ? 217 THR A CA  1 
ATOM   1458  C  C   . THR A 1 224 ? 129.446 179.423 139.110 1.00 62.91  ? 217 THR A C   1 
ATOM   1459  O  O   . THR A 1 224 ? 129.803 180.453 139.683 1.00 62.91  ? 217 THR A O   1 
ATOM   1460  C  CB  . THR A 1 224 ? 128.447 178.705 141.282 1.00 62.91  ? 217 THR A CB  1 
ATOM   1461  O  OG1 . THR A 1 224 ? 129.574 179.046 142.099 1.00 62.91  ? 217 THR A OG1 1 
ATOM   1462  C  CG2 . THR A 1 224 ? 127.636 177.617 141.969 1.00 62.91  ? 217 THR A CG2 1 
ATOM   1463  N  N   . LYS A 1 231 ? 133.363 178.933 145.679 1.00 64.15  ? 224 LYS A N   1 
ATOM   1464  C  CA  . LYS A 1 231 ? 132.693 179.017 144.387 1.00 64.15  ? 224 LYS A CA  1 
ATOM   1465  C  C   . LYS A 1 231 ? 132.138 177.664 143.962 1.00 64.15  ? 224 LYS A C   1 
ATOM   1466  O  O   . LYS A 1 231 ? 131.151 177.590 143.230 1.00 64.15  ? 224 LYS A O   1 
ATOM   1467  C  CB  . LYS A 1 231 ? 133.652 179.544 143.318 1.00 64.15  ? 224 LYS A CB  1 
ATOM   1468  C  CG  . LYS A 1 231 ? 134.028 181.006 143.481 1.00 64.15  ? 224 LYS A CG  1 
ATOM   1469  C  CD  . LYS A 1 231 ? 134.964 181.456 142.371 1.00 64.15  ? 224 LYS A CD  1 
ATOM   1470  C  CE  . LYS A 1 231 ? 135.299 182.933 142.494 1.00 64.15  ? 224 LYS A CE  1 
ATOM   1471  N  NZ  . LYS A 1 231 ? 136.247 183.375 141.435 1.00 64.15  ? 224 LYS A NZ  1 
ATOM   1472  N  N   . CYS A 1 232 ? 132.779 176.593 144.422 1.00 58.55  ? 225 CYS A N   1 
ATOM   1473  C  CA  . CYS A 1 232 ? 132.400 175.238 144.054 1.00 58.55  ? 225 CYS A CA  1 
ATOM   1474  C  C   . CYS A 1 232 ? 132.261 174.380 145.301 1.00 58.55  ? 225 CYS A C   1 
ATOM   1475  O  O   . CYS A 1 232 ? 133.078 174.469 146.222 1.00 58.55  ? 225 CYS A O   1 
ATOM   1476  C  CB  . CYS A 1 232 ? 133.426 174.617 143.100 1.00 58.55  ? 225 CYS A CB  1 
ATOM   1477  S  SG  . CYS A 1 232 ? 135.141 174.832 143.613 1.00 58.55  ? 225 CYS A SG  1 
ATOM   1478  N  N   . SER A 1 233 ? 131.225 173.546 145.321 1.00 47.13  ? 226 SER A N   1 
ATOM   1479  C  CA  . SER A 1 233 ? 130.964 172.634 146.422 1.00 47.13  ? 226 SER A CA  1 
ATOM   1480  C  C   . SER A 1 233 ? 130.929 171.211 145.890 1.00 47.13  ? 226 SER A C   1 
ATOM   1481  O  O   . SER A 1 233 ? 130.735 170.986 144.693 1.00 47.13  ? 226 SER A O   1 
ATOM   1482  C  CB  . SER A 1 233 ? 129.643 172.963 147.124 1.00 47.13  ? 226 SER A CB  1 
ATOM   1483  O  OG  . SER A 1 233 ? 128.584 173.064 146.190 1.00 47.13  ? 226 SER A OG  1 
ATOM   1484  N  N   . VAL A 1 234 ? 131.123 170.247 146.791 1.00 42.68  ? 227 VAL A N   1 
ATOM   1485  C  CA  . VAL A 1 234 ? 131.197 168.853 146.374 1.00 42.68  ? 227 VAL A CA  1 
ATOM   1486  C  C   . VAL A 1 234 ? 129.832 168.370 145.901 1.00 42.68  ? 227 VAL A C   1 
ATOM   1487  O  O   . VAL A 1 234 ? 128.780 168.838 146.356 1.00 42.68  ? 227 VAL A O   1 
ATOM   1488  C  CB  . VAL A 1 234 ? 131.737 167.966 147.511 1.00 42.68  ? 227 VAL A CB  1 
ATOM   1489  C  CG1 . VAL A 1 234 ? 132.920 168.632 148.169 1.00 42.68  ? 227 VAL A CG1 1 
ATOM   1490  C  CG2 . VAL A 1 234 ? 130.650 167.674 148.531 1.00 42.68  ? 227 VAL A CG2 1 
ATOM   1491  N  N   . VAL A 1 235 ? 129.853 167.438 144.951 1.00 36.91  ? 228 VAL A N   1 
ATOM   1492  C  CA  . VAL A 1 235 ? 128.654 166.802 144.424 1.00 36.91  ? 228 VAL A CA  1 
ATOM   1493  C  C   . VAL A 1 235 ? 128.731 165.287 144.552 1.00 36.91  ? 228 VAL A C   1 
ATOM   1494  O  O   . VAL A 1 235 ? 127.797 164.645 145.039 1.00 36.91  ? 228 VAL A O   1 
ATOM   1495  C  CB  . VAL A 1 235 ? 128.400 167.211 142.957 1.00 36.91  ? 228 VAL A CB  1 
ATOM   1496  C  CG1 . VAL A 1 235 ? 127.101 166.625 142.455 1.00 36.91  ? 228 VAL A CG1 1 
ATOM   1497  C  CG2 . VAL A 1 235 ? 128.362 168.708 142.844 1.00 36.91  ? 228 VAL A CG2 1 
ATOM   1498  N  N   . LEU A 1 236 ? 129.845 164.699 144.127 1.00 36.75  ? 229 LEU A N   1 
ATOM   1499  C  CA  . LEU A 1 236 ? 130.030 163.257 144.216 1.00 36.75  ? 229 LEU A CA  1 
ATOM   1500  C  C   . LEU A 1 236 ? 131.364 162.949 144.875 1.00 36.75  ? 229 LEU A C   1 
ATOM   1501  O  O   . LEU A 1 236 ? 132.360 163.634 144.637 1.00 36.75  ? 229 LEU A O   1 
ATOM   1502  C  CB  . LEU A 1 236 ? 129.978 162.588 142.838 1.00 36.75  ? 229 LEU A CB  1 
ATOM   1503  C  CG  . LEU A 1 236 ? 128.628 162.568 142.128 1.00 36.75  ? 229 LEU A CG  1 
ATOM   1504  C  CD1 . LEU A 1 236 ? 128.700 161.685 140.899 1.00 36.75  ? 229 LEU A CD1 1 
ATOM   1505  C  CD2 . LEU A 1 236 ? 127.542 162.092 143.069 1.00 36.75  ? 229 LEU A CD2 1 
ATOM   1506  N  N   . GLY A 1 237 ? 131.381 161.897 145.688 1.00 38.80  ? 230 GLY A N   1 
ATOM   1507  C  CA  . GLY A 1 237 ? 132.586 161.500 146.374 1.00 38.80  ? 230 GLY A CA  1 
ATOM   1508  C  C   . GLY A 1 237 ? 132.434 160.205 147.142 1.00 38.80  ? 230 GLY A C   1 
ATOM   1509  O  O   . GLY A 1 237 ? 131.450 159.475 146.992 1.00 38.80  ? 230 GLY A O   1 
ATOM   1510  N  N   . PRO A 1 238 ? 133.416 159.897 147.995 1.00 38.60  ? 231 PRO A N   1 
ATOM   1511  C  CA  . PRO A 1 238 ? 133.384 158.633 148.745 1.00 38.60  ? 231 PRO A CA  1 
ATOM   1512  C  C   . PRO A 1 238 ? 132.297 158.556 149.805 1.00 38.60  ? 231 PRO A C   1 
ATOM   1513  O  O   . PRO A 1 238 ? 132.246 157.559 150.534 1.00 38.60  ? 231 PRO A O   1 
ATOM   1514  C  CB  . PRO A 1 238 ? 134.778 158.578 149.387 1.00 38.60  ? 231 PRO A CB  1 
ATOM   1515  C  CG  . PRO A 1 238 ? 135.223 159.992 149.444 1.00 38.60  ? 231 PRO A CG  1 
ATOM   1516  C  CD  . PRO A 1 238 ? 134.666 160.639 148.218 1.00 38.60  ? 231 PRO A CD  1 
ATOM   1517  N  N   . LYS A 1 239 ? 131.434 159.564 149.929 1.00 43.10  ? 232 LYS A N   1 
ATOM   1518  C  CA  . LYS A 1 239 ? 130.320 159.505 150.864 1.00 43.10  ? 232 LYS A CA  1 
ATOM   1519  C  C   . LYS A 1 239 ? 128.973 159.843 150.241 1.00 43.10  ? 232 LYS A C   1 
ATOM   1520  O  O   . LYS A 1 239 ? 127.946 159.618 150.889 1.00 43.10  ? 232 LYS A O   1 
ATOM   1521  C  CB  . LYS A 1 239 ? 130.566 160.442 152.058 1.00 43.10  ? 232 LYS A CB  1 
ATOM   1522  C  CG  . LYS A 1 239 ? 131.823 160.118 152.852 1.00 43.10  ? 232 LYS A CG  1 
ATOM   1523  C  CD  . LYS A 1 239 ? 131.991 161.055 154.037 1.00 43.10  ? 232 LYS A CD  1 
ATOM   1524  C  CE  . LYS A 1 239 ? 133.445 161.451 154.227 1.00 43.10  ? 232 LYS A CE  1 
ATOM   1525  N  NZ  . LYS A 1 239 ? 133.906 162.397 153.173 1.00 43.10  ? 232 LYS A NZ  1 
ATOM   1526  N  N   . TRP A 1 240 ? 128.940 160.368 149.020 1.00 39.57  ? 233 TRP A N   1 
ATOM   1527  C  CA  . TRP A 1 240 ? 127.692 160.662 148.315 1.00 39.57  ? 233 TRP A CA  1 
ATOM   1528  C  C   . TRP A 1 240 ? 127.687 159.918 146.988 1.00 39.57  ? 233 TRP A C   1 
ATOM   1529  O  O   . TRP A 1 240 ? 128.219 160.430 145.986 1.00 39.57  ? 233 TRP A O   1 
ATOM   1530  C  CB  . TRP A 1 240 ? 127.532 162.163 148.085 1.00 39.57  ? 233 TRP A CB  1 
ATOM   1531  C  CG  . TRP A 1 240 ? 127.611 162.986 149.326 1.00 39.57  ? 233 TRP A CG  1 
ATOM   1532  C  CD1 . TRP A 1 240 ? 126.582 163.320 150.154 1.00 39.57  ? 233 TRP A CD1 1 
ATOM   1533  C  CD2 . TRP A 1 240 ? 128.786 163.587 149.883 1.00 39.57  ? 233 TRP A CD2 1 
ATOM   1534  N  NE1 . TRP A 1 240 ? 127.042 164.092 151.193 1.00 39.57  ? 233 TRP A NE1 1 
ATOM   1535  C  CE2 . TRP A 1 240 ? 128.392 164.270 151.049 1.00 39.57  ? 233 TRP A CE2 1 
ATOM   1536  C  CE3 . TRP A 1 240 ? 130.132 163.614 149.509 1.00 39.57  ? 233 TRP A CE3 1 
ATOM   1537  C  CZ2 . TRP A 1 240 ? 129.295 164.970 151.844 1.00 39.57  ? 233 TRP A CZ2 1 
ATOM   1538  C  CZ3 . TRP A 1 240 ? 131.027 164.310 150.298 1.00 39.57  ? 233 TRP A CZ3 1 
ATOM   1539  C  CH2 . TRP A 1 240 ? 130.605 164.978 151.452 1.00 39.57  ? 233 TRP A CH2 1 
ATOM   1540  N  N   . PRO A 1 241 ? 127.137 158.706 146.930 1.00 30.69  ? 234 PRO A N   1 
ATOM   1541  C  CA  . PRO A 1 241 ? 127.082 157.989 145.645 1.00 30.69  ? 234 PRO A CA  1 
ATOM   1542  C  C   . PRO A 1 241 ? 126.366 158.751 144.542 1.00 30.69  ? 234 PRO A C   1 
ATOM   1543  O  O   . PRO A 1 241 ? 126.788 158.687 143.383 1.00 30.69  ? 234 PRO A O   1 
ATOM   1544  C  CB  . PRO A 1 241 ? 126.331 156.699 145.994 1.00 30.69  ? 234 PRO A CB  1 
ATOM   1545  C  CG  . PRO A 1 241 ? 126.378 156.573 147.480 1.00 30.69  ? 234 PRO A CG  1 
ATOM   1546  C  CD  . PRO A 1 241 ? 126.963 157.809 148.081 1.00 30.69  ? 234 PRO A CD  1 
ATOM   1547  N  N   . SER A 1 242 ? 125.294 159.470 144.866 1.00 31.80  ? 235 SER A N   1 
ATOM   1548  C  CA  . SER A 1 242 ? 124.501 160.150 143.853 1.00 31.80  ? 235 SER A CA  1 
ATOM   1549  C  C   . SER A 1 242 ? 124.057 161.506 144.379 1.00 31.80  ? 235 SER A C   1 
ATOM   1550  O  O   . SER A 1 242 ? 123.950 161.720 145.588 1.00 31.80  ? 235 SER A O   1 
ATOM   1551  C  CB  . SER A 1 242 ? 123.277 159.326 143.451 1.00 31.80  ? 235 SER A CB  1 
ATOM   1552  O  OG  . SER A 1 242 ? 122.393 159.179 144.547 1.00 31.80  ? 235 SER A OG  1 
ATOM   1553  N  N   . HIS A 1 243 ? 123.789 162.421 143.450 1.00 35.98  ? 236 HIS A N   1 
ATOM   1554  C  CA  . HIS A 1 243 ? 123.298 163.742 143.809 1.00 35.98  ? 236 HIS A CA  1 
ATOM   1555  C  C   . HIS A 1 243 ? 122.242 164.201 142.817 1.00 35.98  ? 236 HIS A C   1 
ATOM   1556  O  O   . HIS A 1 243 ? 122.405 164.052 141.602 1.00 35.98  ? 236 HIS A O   1 
ATOM   1557  C  CB  . HIS A 1 243 ? 124.430 164.770 143.868 1.00 35.98  ? 236 HIS A CB  1 
ATOM   1558  C  CG  . HIS A 1 243 ? 124.075 166.014 144.622 1.00 35.98  ? 236 HIS A CG  1 
ATOM   1559  N  ND1 . HIS A 1 243 ? 124.958 167.057 144.799 1.00 35.98  ? 236 HIS A ND1 1 
ATOM   1560  C  CD2 . HIS A 1 243 ? 122.934 166.379 145.252 1.00 35.98  ? 236 HIS A CD2 1 
ATOM   1561  C  CE1 . HIS A 1 243 ? 124.376 168.012 145.501 1.00 35.98  ? 236 HIS A CE1 1 
ATOM   1562  N  NE2 . HIS A 1 243 ? 123.146 167.626 145.789 1.00 35.98  ? 236 HIS A NE2 1 
ATOM   1563  N  N   . TYR A 1 244 ? 121.161 164.759 143.351 1.00 35.91  ? 237 TYR A N   1 
ATOM   1564  C  CA  . TYR A 1 244 ? 120.124 165.372 142.536 1.00 35.91  ? 237 TYR A CA  1 
ATOM   1565  C  C   . TYR A 1 244 ? 120.549 166.777 142.132 1.00 35.91  ? 237 TYR A C   1 
ATOM   1566  O  O   . TYR A 1 244 ? 121.087 167.534 142.943 1.00 35.91  ? 237 TYR A O   1 
ATOM   1567  C  CB  . TYR A 1 244 ? 118.808 165.421 143.311 1.00 35.91  ? 237 TYR A CB  1 
ATOM   1568  C  CG  . TYR A 1 244 ? 118.228 164.058 143.613 1.00 35.91  ? 237 TYR A CG  1 
ATOM   1569  C  CD1 . TYR A 1 244 ? 117.485 163.374 142.665 1.00 35.91  ? 237 TYR A CD1 1 
ATOM   1570  C  CD2 . TYR A 1 244 ? 118.446 163.445 144.838 1.00 35.91  ? 237 TYR A CD2 1 
ATOM   1571  C  CE1 . TYR A 1 244 ? 116.957 162.128 142.934 1.00 35.91  ? 237 TYR A CE1 1 
ATOM   1572  C  CE2 . TYR A 1 244 ? 117.925 162.197 145.114 1.00 35.91  ? 237 TYR A CE2 1 
ATOM   1573  C  CZ  . TYR A 1 244 ? 117.182 161.544 144.158 1.00 35.91  ? 237 TYR A CZ  1 
ATOM   1574  O  OH  . TYR A 1 244 ? 116.660 160.300 144.426 1.00 35.91  ? 237 TYR A OH  1 
ATOM   1575  N  N   . LEU A 1 245 ? 120.307 167.123 140.873 1.00 40.36  ? 238 LEU A N   1 
ATOM   1576  C  CA  . LEU A 1 245 ? 120.727 168.403 140.326 1.00 40.36  ? 238 LEU A CA  1 
ATOM   1577  C  C   . LEU A 1 245 ? 119.548 169.362 140.217 1.00 40.36  ? 238 LEU A C   1 
ATOM   1578  O  O   . LEU A 1 245 ? 118.434 168.970 139.863 1.00 40.36  ? 238 LEU A O   1 
ATOM   1579  C  CB  . LEU A 1 245 ? 121.372 168.224 138.951 1.00 40.36  ? 238 LEU A CB  1 
ATOM   1580  C  CG  . LEU A 1 245 ? 122.668 167.417 138.905 1.00 40.36  ? 238 LEU A CG  1 
ATOM   1581  C  CD1 . LEU A 1 245 ? 123.113 167.212 137.470 1.00 40.36  ? 238 LEU A CD1 1 
ATOM   1582  C  CD2 . LEU A 1 245 ? 123.750 168.112 139.707 1.00 40.36  ? 238 LEU A CD2 1 
ATOM   1583  N  N   . MET A 1 246 ? 119.810 170.629 140.528 1.00 52.99  ? 239 MET A N   1 
ATOM   1584  C  CA  . MET A 1 246 ? 118.828 171.700 140.398 1.00 52.99  ? 239 MET A CA  1 
ATOM   1585  C  C   . MET A 1 246 ? 119.167 172.503 139.148 1.00 52.99  ? 239 MET A C   1 
ATOM   1586  O  O   . MET A 1 246 ? 120.187 173.197 139.109 1.00 52.99  ? 239 MET A O   1 
ATOM   1587  C  CB  . MET A 1 246 ? 118.825 172.591 141.637 1.00 52.99  ? 239 MET A CB  1 
ATOM   1588  C  CG  . MET A 1 246 ? 118.762 171.835 142.952 1.00 52.99  ? 239 MET A CG  1 
ATOM   1589  S  SD  . MET A 1 246 ? 118.755 172.916 144.397 1.00 52.99  ? 239 MET A SD  1 
ATOM   1590  C  CE  . MET A 1 246 ? 118.687 174.535 143.632 1.00 52.99  ? 239 MET A CE  1 
ATOM   1591  N  N   . VAL A 1 247 ? 118.315 172.410 138.133 1.00 57.89  ? 240 VAL A N   1 
ATOM   1592  C  CA  . VAL A 1 247 ? 118.535 173.055 136.845 1.00 57.89  ? 240 VAL A CA  1 
ATOM   1593  C  C   . VAL A 1 247 ? 117.288 173.855 136.495 1.00 57.89  ? 240 VAL A C   1 
ATOM   1594  O  O   . VAL A 1 247 ? 116.176 173.365 136.696 1.00 57.89  ? 240 VAL A O   1 
ATOM   1595  C  CB  . VAL A 1 247 ? 118.846 172.045 135.727 1.00 57.89  ? 240 VAL A CB  1 
ATOM   1596  C  CG1 . VAL A 1 247 ? 118.944 172.751 134.398 1.00 57.89  ? 240 VAL A CG1 1 
ATOM   1597  C  CG2 . VAL A 1 247 ? 120.139 171.325 136.030 1.00 57.89  ? 240 VAL A CG2 1 
ATOM   1598  N  N   . PRO A 1 248 ? 117.422 175.073 135.980 1.00 62.58  ? 241 PRO A N   1 
ATOM   1599  C  CA  . PRO A 1 248 ? 116.254 175.827 135.521 1.00 62.58  ? 241 PRO A CA  1 
ATOM   1600  C  C   . PRO A 1 248 ? 115.878 175.475 134.088 1.00 62.58  ? 241 PRO A C   1 
ATOM   1601  O  O   . PRO A 1 248 ? 116.628 174.831 133.353 1.00 62.58  ? 241 PRO A O   1 
ATOM   1602  C  CB  . PRO A 1 248 ? 116.729 177.282 135.617 1.00 62.58  ? 241 PRO A CB  1 
ATOM   1603  C  CG  . PRO A 1 248 ? 118.193 177.193 135.349 1.00 62.58  ? 241 PRO A CG  1 
ATOM   1604  C  CD  . PRO A 1 248 ? 118.658 175.870 135.912 1.00 62.58  ? 241 PRO A CD  1 
ATOM   1605  N  N   . GLY A 1 249 ? 114.688 175.920 133.703 1.00 65.22  ? 242 GLY A N   1 
ATOM   1606  C  CA  . GLY A 1 249 ? 114.200 175.676 132.363 1.00 65.22  ? 242 GLY A CA  1 
ATOM   1607  C  C   . GLY A 1 249 ? 114.845 176.587 131.335 1.00 65.22  ? 242 GLY A C   1 
ATOM   1608  O  O   . GLY A 1 249 ? 115.567 177.535 131.647 1.00 65.22  ? 242 GLY A O   1 
ATOM   1609  N  N   . GLY A 1 250 ? 114.569 176.282 130.070 1.00 64.19  ? 243 GLY A N   1 
ATOM   1610  C  CA  . GLY A 1 250 ? 115.122 177.042 128.966 1.00 64.19  ? 243 GLY A CA  1 
ATOM   1611  C  C   . GLY A 1 250 ? 116.446 176.491 128.481 1.00 64.19  ? 243 GLY A C   1 
ATOM   1612  O  O   . GLY A 1 250 ? 116.594 175.276 128.313 1.00 64.19  ? 243 GLY A O   1 
ATOM   1613  N  N   . LYS A 1 251 ? 117.404 177.379 128.233 1.00 64.24  ? 244 LYS A N   1 
ATOM   1614  C  CA  . LYS A 1 251 ? 118.776 177.007 127.925 1.00 64.24  ? 244 LYS A CA  1 
ATOM   1615  C  C   . LYS A 1 251 ? 119.613 177.101 129.191 1.00 64.24  ? 244 LYS A C   1 
ATOM   1616  O  O   . LYS A 1 251 ? 119.471 178.052 129.965 1.00 64.24  ? 244 LYS A O   1 
ATOM   1617  C  CB  . LYS A 1 251 ? 119.377 177.926 126.859 1.00 64.24  ? 244 LYS A CB  1 
ATOM   1618  C  CG  . LYS A 1 251 ? 118.784 177.798 125.473 1.00 64.24  ? 244 LYS A CG  1 
ATOM   1619  C  CD  . LYS A 1 251 ? 119.584 178.633 124.483 1.00 64.24  ? 244 LYS A CD  1 
ATOM   1620  C  CE  . LYS A 1 251 ? 118.918 178.684 123.119 1.00 64.24  ? 244 LYS A CE  1 
ATOM   1621  N  NZ  . LYS A 1 251 ? 119.685 179.525 122.159 1.00 64.24  ? 244 LYS A NZ  1 
ATOM   1622  N  N   . HIS A 1 252 ? 120.487 176.121 129.402 1.00 59.16  ? 245 HIS A N   1 
ATOM   1623  C  CA  . HIS A 1 252 ? 121.394 176.213 130.536 1.00 59.16  ? 245 HIS A CA  1 
ATOM   1624  C  C   . HIS A 1 252 ? 122.595 175.309 130.306 1.00 59.16  ? 245 HIS A C   1 
ATOM   1625  O  O   . HIS A 1 252 ? 122.512 174.306 129.590 1.00 59.16  ? 245 HIS A O   1 
ATOM   1626  C  CB  . HIS A 1 252 ? 120.699 175.845 131.850 1.00 59.16  ? 245 HIS A CB  1 
ATOM   1627  C  CG  . HIS A 1 252 ? 121.490 176.205 133.068 1.00 59.16  ? 245 HIS A CG  1 
ATOM   1628  N  ND1 . HIS A 1 252 ? 122.001 175.262 133.931 1.00 59.16  ? 245 HIS A ND1 1 
ATOM   1629  C  CD2 . HIS A 1 252 ? 121.862 177.409 133.563 1.00 59.16  ? 245 HIS A CD2 1 
ATOM   1630  C  CE1 . HIS A 1 252 ? 122.651 175.868 134.908 1.00 59.16  ? 245 HIS A CE1 1 
ATOM   1631  N  NE2 . HIS A 1 252 ? 122.582 177.172 134.708 1.00 59.16  ? 245 HIS A NE2 1 
ATOM   1632  N  N   . ASN A 1 253 ? 123.709 175.682 130.927 1.00 54.79  ? 246 ASN A N   1 
ATOM   1633  C  CA  . ASN A 1 253 ? 124.929 174.893 130.908 1.00 54.79  ? 246 ASN A CA  1 
ATOM   1634  C  C   . ASN A 1 253 ? 125.476 174.801 132.322 1.00 54.79  ? 246 ASN A C   1 
ATOM   1635  O  O   . ASN A 1 253 ? 125.477 175.788 133.062 1.00 54.79  ? 246 ASN A O   1 
ATOM   1636  C  CB  . ASN A 1 253 ? 125.973 175.507 129.974 1.00 54.79  ? 246 ASN A CB  1 
ATOM   1637  C  CG  . ASN A 1 253 ? 125.456 175.677 128.561 1.00 54.79  ? 246 ASN A CG  1 
ATOM   1638  O  OD1 . ASN A 1 253 ? 125.168 174.699 127.872 1.00 54.79  ? 246 ASN A OD1 1 
ATOM   1639  N  ND2 . ASN A 1 253 ? 125.332 176.923 128.121 1.00 54.79  ? 246 ASN A ND2 1 
ATOM   1640  N  N   . MET A 1 254 ? 125.933 173.611 132.693 1.00 48.76  ? 247 MET A N   1 
ATOM   1641  C  CA  . MET A 1 254 ? 126.518 173.367 134.002 1.00 48.76  ? 247 MET A CA  1 
ATOM   1642  C  C   . MET A 1 254 ? 127.932 172.839 133.833 1.00 48.76  ? 247 MET A C   1 
ATOM   1643  O  O   . MET A 1 254 ? 128.200 172.034 132.935 1.00 48.76  ? 247 MET A O   1 
ATOM   1644  C  CB  . MET A 1 254 ? 125.691 172.371 134.813 1.00 48.76  ? 247 MET A CB  1 
ATOM   1645  C  CG  . MET A 1 254 ? 124.343 172.888 135.256 1.00 48.76  ? 247 MET A CG  1 
ATOM   1646  S  SD  . MET A 1 254 ? 123.658 171.841 136.545 1.00 48.76  ? 247 MET A SD  1 
ATOM   1647  C  CE  . MET A 1 254 ? 124.959 171.939 137.764 1.00 48.76  ? 247 MET A CE  1 
ATOM   1648  N  N   . ASP A 1 255 ? 128.827 173.286 134.708 1.00 47.34  ? 248 ASP A N   1 
ATOM   1649  C  CA  . ASP A 1 255 ? 130.228 172.900 134.675 1.00 47.34  ? 248 ASP A CA  1 
ATOM   1650  C  C   . ASP A 1 255 ? 130.537 172.024 135.880 1.00 47.34  ? 248 ASP A C   1 
ATOM   1651  O  O   . ASP A 1 255 ? 130.257 172.408 137.021 1.00 47.34  ? 248 ASP A O   1 
ATOM   1652  C  CB  . ASP A 1 255 ? 131.132 174.133 134.666 1.00 47.34  ? 248 ASP A CB  1 
ATOM   1653  C  CG  . ASP A 1 255 ? 131.275 174.737 133.285 1.00 47.34  ? 248 ASP A CG  1 
ATOM   1654  O  OD1 . ASP A 1 255 ? 130.697 174.180 132.330 1.00 47.34  ? 248 ASP A OD1 1 
ATOM   1655  O  OD2 . ASP A 1 255 ? 131.962 175.772 133.155 1.00 47.34  ? 248 ASP A OD2 1 
ATOM   1656  N  N   . PHE A 1 256 ? 131.107 170.852 135.624 1.00 39.82  ? 249 PHE A N   1 
ATOM   1657  C  CA  . PHE A 1 256 ? 131.520 169.926 136.664 1.00 39.82  ? 249 PHE A CA  1 
ATOM   1658  C  C   . PHE A 1 256 ? 133.018 169.695 136.553 1.00 39.82  ? 249 PHE A C   1 
ATOM   1659  O  O   . PHE A 1 256 ? 133.559 169.597 135.447 1.00 39.82  ? 249 PHE A O   1 
ATOM   1660  C  CB  . PHE A 1 256 ? 130.778 168.594 136.549 1.00 39.82  ? 249 PHE A CB  1 
ATOM   1661  C  CG  . PHE A 1 256 ? 129.321 168.680 136.885 1.00 39.82  ? 249 PHE A CG  1 
ATOM   1662  C  CD1 . PHE A 1 256 ? 128.872 168.368 138.154 1.00 39.82  ? 249 PHE A CD1 1 
ATOM   1663  C  CD2 . PHE A 1 256 ? 128.399 169.074 135.935 1.00 39.82  ? 249 PHE A CD2 1 
ATOM   1664  C  CE1 . PHE A 1 256 ? 127.532 168.443 138.465 1.00 39.82  ? 249 PHE A CE1 1 
ATOM   1665  C  CE2 . PHE A 1 256 ? 127.059 169.153 136.242 1.00 39.82  ? 249 PHE A CE2 1 
ATOM   1666  C  CZ  . PHE A 1 256 ? 126.625 168.836 137.509 1.00 39.82  ? 249 PHE A CZ  1 
ATOM   1667  N  N   . TYR A 1 257 ? 133.684 169.618 137.697 1.00 38.98  ? 250 TYR A N   1 
ATOM   1668  C  CA  . TYR A 1 257 ? 135.117 169.369 137.754 1.00 38.98  ? 250 TYR A CA  1 
ATOM   1669  C  C   . TYR A 1 257 ? 135.356 168.029 138.430 1.00 38.98  ? 250 TYR A C   1 
ATOM   1670  O  O   . TYR A 1 257 ? 134.833 167.780 139.520 1.00 38.98  ? 250 TYR A O   1 
ATOM   1671  C  CB  . TYR A 1 257 ? 135.840 170.490 138.501 1.00 38.98  ? 250 TYR A CB  1 
ATOM   1672  C  CG  . TYR A 1 257 ? 135.956 171.768 137.705 1.00 38.98  ? 250 TYR A CG  1 
ATOM   1673  C  CD1 . TYR A 1 257 ? 136.937 171.917 136.738 1.00 38.98  ? 250 TYR A CD1 1 
ATOM   1674  C  CD2 . TYR A 1 257 ? 135.081 172.821 137.915 1.00 38.98  ? 250 TYR A CD2 1 
ATOM   1675  C  CE1 . TYR A 1 257 ? 137.045 173.079 136.006 1.00 38.98  ? 250 TYR A CE1 1 
ATOM   1676  C  CE2 . TYR A 1 257 ? 135.181 173.986 137.186 1.00 38.98  ? 250 TYR A CE2 1 
ATOM   1677  C  CZ  . TYR A 1 257 ? 136.165 174.110 136.234 1.00 38.98  ? 250 TYR A CZ  1 
ATOM   1678  O  OH  . TYR A 1 257 ? 136.268 175.272 135.506 1.00 38.98  ? 250 TYR A OH  1 
ATOM   1679  N  N   . VAL A 1 258 ? 136.146 167.174 137.786 1.00 37.19  ? 251 VAL A N   1 
ATOM   1680  C  CA  . VAL A 1 258 ? 136.345 165.797 138.217 1.00 37.19  ? 251 VAL A CA  1 
ATOM   1681  C  C   . VAL A 1 258 ? 137.811 165.595 138.566 1.00 37.19  ? 251 VAL A C   1 
ATOM   1682  O  O   . VAL A 1 258 ? 138.696 166.028 137.818 1.00 37.19  ? 251 VAL A O   1 
ATOM   1683  C  CB  . VAL A 1 258 ? 135.908 164.799 137.131 1.00 37.19  ? 251 VAL A CB  1 
ATOM   1684  C  CG1 . VAL A 1 258 ? 135.806 163.410 137.711 1.00 37.19  ? 251 VAL A CG1 1 
ATOM   1685  C  CG2 . VAL A 1 258 ? 134.587 165.225 136.528 1.00 37.19  ? 251 VAL A CG2 1 
ATOM   1686  N  N   . GLU A 1 259 ? 138.065 164.943 139.700 1.00 38.74  ? 252 GLU A N   1 
ATOM   1687  C  CA  . GLU A 1 259 ? 139.413 164.572 140.104 1.00 38.74  ? 252 GLU A CA  1 
ATOM   1688  C  C   . GLU A 1 259 ? 139.421 163.148 140.638 1.00 38.74  ? 252 GLU A C   1 
ATOM   1689  O  O   . GLU A 1 259 ? 138.538 162.755 141.407 1.00 38.74  ? 252 GLU A O   1 
ATOM   1690  C  CB  . GLU A 1 259 ? 139.972 165.532 141.165 1.00 38.74  ? 252 GLU A CB  1 
ATOM   1691  C  CG  . GLU A 1 259 ? 139.150 165.628 142.441 1.00 38.74  ? 252 GLU A CG  1 
ATOM   1692  C  CD  . GLU A 1 259 ? 139.787 166.540 143.473 1.00 38.74  ? 252 GLU A CD  1 
ATOM   1693  O  OE1 . GLU A 1 259 ? 140.915 167.016 143.229 1.00 38.74  ? 252 GLU A OE1 1 
ATOM   1694  O  OE2 . GLU A 1 259 ? 139.160 166.786 144.524 1.00 38.74  ? 252 GLU A OE2 1 
ATOM   1695  N  N   . ALA A 1 260 ? 140.425 162.379 140.230 1.00 35.01  ? 253 ALA A N   1 
ATOM   1696  C  CA  . ALA A 1 260 ? 140.593 161.005 140.673 1.00 35.01  ? 253 ALA A CA  1 
ATOM   1697  C  C   . ALA A 1 260 ? 141.361 160.964 141.986 1.00 35.01  ? 253 ALA A C   1 
ATOM   1698  O  O   . ALA A 1 260 ? 142.005 161.935 142.387 1.00 35.01  ? 253 ALA A O   1 
ATOM   1699  C  CB  . ALA A 1 260 ? 141.320 160.175 139.613 1.00 35.01  ? 253 ALA A CB  1 
ATOM   1700  N  N   . LEU A 1 261 ? 141.284 159.818 142.660 1.00 34.64  ? 254 LEU A N   1 
ATOM   1701  C  CA  . LEU A 1 261 ? 141.896 159.653 143.971 1.00 34.64  ? 254 LEU A CA  1 
ATOM   1702  C  C   . LEU A 1 261 ? 142.963 158.573 144.030 1.00 34.64  ? 254 LEU A C   1 
ATOM   1703  O  O   . LEU A 1 261 ? 143.886 158.687 144.837 1.00 34.64  ? 254 LEU A O   1 
ATOM   1704  C  CB  . LEU A 1 261 ? 140.824 159.338 145.021 1.00 34.64  ? 254 LEU A CB  1 
ATOM   1705  C  CG  . LEU A 1 261 ? 140.388 160.479 145.939 1.00 34.64  ? 254 LEU A CG  1 
ATOM   1706  C  CD1 . LEU A 1 261 ? 141.427 160.703 147.020 1.00 34.64  ? 254 LEU A CD1 1 
ATOM   1707  C  CD2 . LEU A 1 261 ? 140.148 161.753 145.152 1.00 34.64  ? 254 LEU A CD2 1 
ATOM   1708  N  N   . ALA A 1 262 ? 142.867 157.534 143.205 1.00 32.51  ? 255 ALA A N   1 
ATOM   1709  C  CA  . ALA A 1 262 ? 143.776 156.400 143.284 1.00 32.51  ? 255 ALA A CA  1 
ATOM   1710  C  C   . ALA A 1 262 ? 144.366 156.091 141.918 1.00 32.51  ? 255 ALA A C   1 
ATOM   1711  O  O   . ALA A 1 262 ? 143.670 156.154 140.901 1.00 32.51  ? 255 ALA A O   1 
ATOM   1712  C  CB  . ALA A 1 262 ? 143.065 155.158 143.830 1.00 32.51  ? 255 ALA A CB  1 
ATOM   1713  N  N   . PHE A 1 263 ? 145.653 155.759 141.903 1.00 30.76  ? 256 PHE A N   1 
ATOM   1714  C  CA  . PHE A 1 263 ? 146.287 155.290 140.685 1.00 30.76  ? 256 PHE A CA  1 
ATOM   1715  C  C   . PHE A 1 263 ? 145.766 153.896 140.340 1.00 30.76  ? 256 PHE A C   1 
ATOM   1716  O  O   . PHE A 1 263 ? 145.295 153.171 141.219 1.00 30.76  ? 256 PHE A O   1 
ATOM   1717  C  CB  . PHE A 1 263 ? 147.803 155.253 140.853 1.00 30.76  ? 256 PHE A CB  1 
ATOM   1718  C  CG  . PHE A 1 263 ? 148.485 156.544 140.508 1.00 30.76  ? 256 PHE A CG  1 
ATOM   1719  C  CD1 . PHE A 1 263 ? 148.387 157.640 141.343 1.00 30.76  ? 256 PHE A CD1 1 
ATOM   1720  C  CD2 . PHE A 1 263 ? 149.222 156.662 139.346 1.00 30.76  ? 256 PHE A CD2 1 
ATOM   1721  C  CE1 . PHE A 1 263 ? 149.017 158.823 141.027 1.00 30.76  ? 256 PHE A CE1 1 
ATOM   1722  C  CE2 . PHE A 1 263 ? 149.850 157.844 139.025 1.00 30.76  ? 256 PHE A CE2 1 
ATOM   1723  C  CZ  . PHE A 1 263 ? 149.747 158.925 139.865 1.00 30.76  ? 256 PHE A CZ  1 
ATOM   1724  N  N   . PRO A 1 264 ? 145.821 153.502 139.068 1.00 31.08  ? 257 PRO A N   1 
ATOM   1725  C  CA  . PRO A 1 264 ? 145.359 152.159 138.702 1.00 31.08  ? 257 PRO A CA  1 
ATOM   1726  C  C   . PRO A 1 264 ? 146.190 151.088 139.389 1.00 31.08  ? 257 PRO A C   1 
ATOM   1727  O  O   . PRO A 1 264 ? 147.396 151.240 139.584 1.00 31.08  ? 257 PRO A O   1 
ATOM   1728  C  CB  . PRO A 1 264 ? 145.537 152.123 137.180 1.00 31.08  ? 257 PRO A CB  1 
ATOM   1729  C  CG  . PRO A 1 264 ? 145.602 153.547 136.766 1.00 31.08  ? 257 PRO A CG  1 
ATOM   1730  C  CD  . PRO A 1 264 ? 146.271 154.261 137.892 1.00 31.08  ? 257 PRO A CD  1 
ATOM   1731  N  N   . ASP A 1 265 ? 145.529 149.996 139.757 1.00 37.21  ? 258 ASP A N   1 
ATOM   1732  C  CA  . ASP A 1 265 ? 146.176 148.903 140.468 1.00 37.21  ? 258 ASP A CA  1 
ATOM   1733  C  C   . ASP A 1 265 ? 145.492 147.602 140.063 1.00 37.21  ? 258 ASP A C   1 
ATOM   1734  O  O   . ASP A 1 265 ? 144.660 147.578 139.152 1.00 37.21  ? 258 ASP A O   1 
ATOM   1735  C  CB  . ASP A 1 265 ? 146.129 149.148 141.980 1.00 37.21  ? 258 ASP A CB  1 
ATOM   1736  C  CG  . ASP A 1 265 ? 147.391 148.697 142.680 1.00 37.21  ? 258 ASP A CG  1 
ATOM   1737  O  OD1 . ASP A 1 265 ? 148.282 148.147 142.001 1.00 37.21  ? 258 ASP A OD1 1 
ATOM   1738  O  OD2 . ASP A 1 265 ? 147.496 148.897 143.908 1.00 37.21  ? 258 ASP A OD2 1 
ATOM   1739  N  N   . THR A 1 266 ? 145.852 146.508 140.738 1.00 40.12  ? 259 THR A N   1 
ATOM   1740  C  CA  . THR A 1 266 ? 145.247 145.217 140.419 1.00 40.12  ? 259 THR A CA  1 
ATOM   1741  C  C   . THR A 1 266 ? 143.755 145.209 140.727 1.00 40.12  ? 259 THR A C   1 
ATOM   1742  O  O   . THR A 1 266 ? 142.963 144.631 139.974 1.00 40.12  ? 259 THR A O   1 
ATOM   1743  C  CB  . THR A 1 266 ? 145.953 144.095 141.177 1.00 40.12  ? 259 THR A CB  1 
ATOM   1744  O  OG1 . THR A 1 266 ? 146.334 144.556 142.478 1.00 40.12  ? 259 THR A OG1 1 
ATOM   1745  C  CG2 . THR A 1 266 ? 147.183 143.635 140.417 1.00 40.12  ? 259 THR A CG2 1 
ATOM   1746  N  N   . ASP A 1 267 ? 143.353 145.836 141.831 1.00 42.85  ? 260 ASP A N   1 
ATOM   1747  C  CA  . ASP A 1 267 ? 141.950 145.871 142.215 1.00 42.85  ? 260 ASP A CA  1 
ATOM   1748  C  C   . ASP A 1 267 ? 141.153 146.931 141.467 1.00 42.85  ? 260 ASP A C   1 
ATOM   1749  O  O   . ASP A 1 267 ? 139.919 146.901 141.515 1.00 42.85  ? 260 ASP A O   1 
ATOM   1750  C  CB  . ASP A 1 267 ? 141.831 146.115 143.720 1.00 42.85  ? 260 ASP A CB  1 
ATOM   1751  C  CG  . ASP A 1 267 ? 142.852 145.332 144.516 1.00 42.85  ? 260 ASP A CG  1 
ATOM   1752  O  OD1 . ASP A 1 267 ? 143.232 144.229 144.071 1.00 42.85  ? 260 ASP A OD1 1 
ATOM   1753  O  OD2 . ASP A 1 267 ? 143.278 145.821 145.583 1.00 42.85  ? 260 ASP A OD2 1 
ATOM   1754  N  N   . PHE A 1 268 ? 141.820 147.856 140.782 1.00 33.50  ? 261 PHE A N   1 
ATOM   1755  C  CA  . PHE A 1 268 ? 141.162 148.964 140.090 1.00 33.50  ? 261 PHE A CA  1 
ATOM   1756  C  C   . PHE A 1 268 ? 141.743 149.069 138.687 1.00 33.50  ? 261 PHE A C   1 
ATOM   1757  O  O   . PHE A 1 268 ? 142.831 149.642 138.507 1.00 33.50  ? 261 PHE A O   1 
ATOM   1758  C  CB  . PHE A 1 268 ? 141.344 150.266 140.863 1.00 33.50  ? 261 PHE A CB  1 
ATOM   1759  C  CG  . PHE A 1 268 ? 140.846 151.484 140.140 1.00 33.50  ? 261 PHE A CG  1 
ATOM   1760  C  CD1 . PHE A 1 268 ? 139.651 151.460 139.446 1.00 33.50  ? 261 PHE A CD1 1 
ATOM   1761  C  CD2 . PHE A 1 268 ? 141.568 152.662 140.172 1.00 33.50  ? 261 PHE A CD2 1 
ATOM   1762  C  CE1 . PHE A 1 268 ? 139.196 152.583 138.788 1.00 33.50  ? 261 PHE A CE1 1 
ATOM   1763  C  CE2 . PHE A 1 268 ? 141.116 153.786 139.517 1.00 33.50  ? 261 PHE A CE2 1 
ATOM   1764  C  CZ  . PHE A 1 268 ? 139.930 153.747 138.825 1.00 33.50  ? 261 PHE A CZ  1 
ATOM   1765  N  N   . PRO A 1 269 ? 141.062 148.523 137.675 1.00 29.98  ? 262 PRO A N   1 
ATOM   1766  C  CA  . PRO A 1 269 ? 141.616 148.574 136.310 1.00 29.98  ? 262 PRO A CA  1 
ATOM   1767  C  C   . PRO A 1 269 ? 141.877 149.984 135.810 1.00 29.98  ? 262 PRO A C   1 
ATOM   1768  O  O   . PRO A 1 269 ? 142.882 150.217 135.127 1.00 29.98  ? 262 PRO A O   1 
ATOM   1769  C  CB  . PRO A 1 269 ? 140.543 147.863 135.475 1.00 29.98  ? 262 PRO A CB  1 
ATOM   1770  C  CG  . PRO A 1 269 ? 139.802 147.013 136.453 1.00 29.98  ? 262 PRO A CG  1 
ATOM   1771  C  CD  . PRO A 1 269 ? 139.785 147.796 137.726 1.00 29.98  ? 262 PRO A CD  1 
ATOM   1772  N  N   . GLY A 1 270 ? 141.004 150.935 136.130 1.00 29.78  ? 263 GLY A N   1 
ATOM   1773  C  CA  . GLY A 1 270 ? 141.250 152.318 135.776 1.00 29.78  ? 263 GLY A CA  1 
ATOM   1774  C  C   . GLY A 1 270 ? 140.095 153.032 135.106 1.00 29.78  ? 263 GLY A C   1 
ATOM   1775  O  O   . GLY A 1 270 ? 140.209 154.216 134.780 1.00 29.78  ? 263 GLY A O   1 
ATOM   1776  N  N   . LEU A 1 271 ? 138.979 152.343 134.900 1.00 28.64  ? 264 LEU A N   1 
ATOM   1777  C  CA  . LEU A 1 271 ? 137.824 152.920 134.225 1.00 28.64  ? 264 LEU A CA  1 
ATOM   1778  C  C   . LEU A 1 271 ? 136.839 153.447 135.258 1.00 28.64  ? 264 LEU A C   1 
ATOM   1779  O  O   . LEU A 1 271 ? 136.474 152.731 136.195 1.00 28.64  ? 264 LEU A O   1 
ATOM   1780  C  CB  . LEU A 1 271 ? 137.141 151.888 133.328 1.00 28.64  ? 264 LEU A CB  1 
ATOM   1781  C  CG  . LEU A 1 271 ? 137.769 151.640 131.956 1.00 28.64  ? 264 LEU A CG  1 
ATOM   1782  C  CD1 . LEU A 1 271 ? 136.808 150.880 131.061 1.00 28.64  ? 264 LEU A CD1 1 
ATOM   1783  C  CD2 . LEU A 1 271 ? 138.181 152.946 131.310 1.00 28.64  ? 264 LEU A CD2 1 
ATOM   1784  N  N   . ILE A 1 272 ? 136.414 154.697 135.087 1.00 27.46  ? 265 ILE A N   1 
ATOM   1785  C  CA  . ILE A 1 272 ? 135.456 155.337 135.980 1.00 27.46  ? 265 ILE A CA  1 
ATOM   1786  C  C   . ILE A 1 272 ? 134.288 155.844 135.147 1.00 27.46  ? 265 ILE A C   1 
ATOM   1787  O  O   . ILE A 1 272 ? 134.487 156.583 134.179 1.00 27.46  ? 265 ILE A O   1 
ATOM   1788  C  CB  . ILE A 1 272 ? 136.101 156.486 136.774 1.00 27.46  ? 265 ILE A CB  1 
ATOM   1789  C  CG1 . ILE A 1 272 ? 137.145 155.939 137.743 1.00 27.46  ? 265 ILE A CG1 1 
ATOM   1790  C  CG2 . ILE A 1 272 ? 135.050 157.264 137.532 1.00 27.46  ? 265 ILE A CG2 1 
ATOM   1791  C  CD1 . ILE A 1 272 ? 137.710 156.980 138.670 1.00 27.46  ? 265 ILE A CD1 1 
ATOM   1792  N  N   . THR A 1 273 ? 133.075 155.462 135.526 1.00 28.20  ? 266 THR A N   1 
ATOM   1793  C  CA  . THR A 1 273 ? 131.879 155.814 134.775 1.00 28.20  ? 266 THR A CA  1 
ATOM   1794  C  C   . THR A 1 273 ? 131.074 156.849 135.544 1.00 28.20  ? 266 THR A C   1 
ATOM   1795  O  O   . THR A 1 273 ? 130.773 156.651 136.724 1.00 28.20  ? 266 THR A O   1 
ATOM   1796  C  CB  . THR A 1 273 ? 131.019 154.577 134.507 1.00 28.20  ? 266 THR A CB  1 
ATOM   1797  O  OG1 . THR A 1 273 ? 131.772 153.620 133.753 1.00 28.20  ? 266 THR A OG1 1 
ATOM   1798  C  CG2 . THR A 1 273 ? 129.770 154.956 133.731 1.00 28.20  ? 266 THR A CG2 1 
ATOM   1799  N  N   . LEU A 1 274 ? 130.722 157.946 134.879 1.00 28.77  ? 267 LEU A N   1 
ATOM   1800  C  CA  . LEU A 1 274 ? 129.825 158.944 135.446 1.00 28.77  ? 267 LEU A CA  1 
ATOM   1801  C  C   . LEU A 1 274 ? 128.546 158.977 134.626 1.00 28.77  ? 267 LEU A C   1 
ATOM   1802  O  O   . LEU A 1 274 ? 128.597 159.102 133.399 1.00 28.77  ? 267 LEU A O   1 
ATOM   1803  C  CB  . LEU A 1 274 ? 130.468 160.330 135.480 1.00 28.77  ? 267 LEU A CB  1 
ATOM   1804  C  CG  . LEU A 1 274 ? 131.266 160.660 136.740 1.00 28.77  ? 267 LEU A CG  1 
ATOM   1805  C  CD1 . LEU A 1 274 ? 132.588 159.919 136.760 1.00 28.77  ? 267 LEU A CD1 1 
ATOM   1806  C  CD2 . LEU A 1 274 ? 131.482 162.149 136.853 1.00 28.77  ? 267 LEU A CD2 1 
ATOM   1807  N  N   . THR A 1 275 ? 127.404 158.883 135.299 1.00 31.15  ? 268 THR A N   1 
ATOM   1808  C  CA  . THR A 1 275 ? 126.134 158.674 134.625 1.00 31.15  ? 268 THR A CA  1 
ATOM   1809  C  C   . THR A 1 275 ? 125.152 159.776 134.991 1.00 31.15  ? 268 THR A C   1 
ATOM   1810  O  O   . THR A 1 275 ? 125.066 160.185 136.154 1.00 31.15  ? 268 THR A O   1 
ATOM   1811  C  CB  . THR A 1 275 ? 125.553 157.308 134.993 1.00 31.15  ? 268 THR A CB  1 
ATOM   1812  O  OG1 . THR A 1 275 ? 126.554 156.299 134.813 1.00 31.15  ? 268 THR A OG1 1 
ATOM   1813  C  CG2 . THR A 1 275 ? 124.360 156.980 134.128 1.00 31.15  ? 268 THR A CG2 1 
ATOM   1814  N  N   . ILE A 1 276 ? 124.468 160.271 133.951 1.00 32.83  ? 269 ILE A N   1 
ATOM   1815  C  CA  . ILE A 1 276 ? 123.397 161.287 134.146 1.00 32.83  ? 269 ILE A CA  1 
ATOM   1816  C  C   . ILE A 1 276 ? 122.085 160.567 133.828 1.00 32.83  ? 269 ILE A C   1 
ATOM   1817  O  O   . ILE A 1 276 ? 122.014 159.906 132.773 1.00 32.83  ? 269 ILE A O   1 
ATOM   1818  C  CB  . ILE A 1 276 ? 123.634 162.527 133.261 1.00 32.83  ? 269 ILE A CB  1 
ATOM   1819  C  CG1 . ILE A 1 276 ? 122.522 163.567 133.422 1.00 32.83  ? 269 ILE A CG1 1 
ATOM   1820  C  CG2 . ILE A 1 276 ? 123.834 162.138 131.803 1.00 32.83  ? 269 ILE A CG2 1 
ATOM   1821  C  CD1 . ILE A 1 276 ? 122.569 164.317 134.732 1.00 32.83  ? 269 ILE A CD1 1 
ATOM   1822  N  N   . SER A 1 277 ? 121.100 160.659 134.715 1.00 33.60  ? 270 SER A N   1 
ATOM   1823  C  CA  . SER A 1 277 ? 119.839 159.949 134.569 1.00 33.60  ? 270 SER A CA  1 
ATOM   1824  C  C   . SER A 1 277 ? 118.674 160.907 134.753 1.00 33.60  ? 270 SER A C   1 
ATOM   1825  O  O   . SER A 1 277 ? 118.668 161.720 135.679 1.00 33.60  ? 270 SER A O   1 
ATOM   1826  C  CB  . SER A 1 277 ? 119.741 158.807 135.581 1.00 33.60  ? 270 SER A CB  1 
ATOM   1827  O  OG  . SER A 1 277 ? 118.489 158.158 135.498 1.00 33.60  ? 270 SER A OG  1 
ATOM   1828  N  N   . LEU A 1 278 ? 117.683 160.806 133.873 1.00 37.48  ? 271 LEU A N   1 
ATOM   1829  C  CA  . LEU A 1 278 ? 116.483 161.628 133.938 1.00 37.48  ? 271 LEU A CA  1 
ATOM   1830  C  C   . LEU A 1 278 ? 115.344 160.791 134.500 1.00 37.48  ? 271 LEU A C   1 
ATOM   1831  O  O   . LEU A 1 278 ? 115.055 159.707 133.984 1.00 37.48  ? 271 LEU A O   1 
ATOM   1832  C  CB  . LEU A 1 278 ? 116.118 162.172 132.556 1.00 37.48  ? 271 LEU A CB  1 
ATOM   1833  C  CG  . LEU A 1 278 ? 114.891 163.077 132.468 1.00 37.48  ? 271 LEU A CG  1 
ATOM   1834  C  CD1 . LEU A 1 278 ? 115.134 164.365 133.222 1.00 37.48  ? 271 LEU A CD1 1 
ATOM   1835  C  CD2 . LEU A 1 278 ? 114.539 163.369 131.023 1.00 37.48  ? 271 LEU A CD2 1 
ATOM   1836  N  N   . LEU A 1 279 ? 114.700 161.291 135.550 1.00 42.62  ? 272 LEU A N   1 
ATOM   1837  C  CA  . LEU A 1 279 ? 113.651 160.568 136.250 1.00 42.62  ? 272 LEU A CA  1 
ATOM   1838  C  C   . LEU A 1 279 ? 112.337 161.328 136.159 1.00 42.62  ? 272 LEU A C   1 
ATOM   1839  O  O   . LEU A 1 279 ? 112.301 162.553 136.314 1.00 42.62  ? 272 LEU A O   1 
ATOM   1840  C  CB  . LEU A 1 279 ? 114.013 160.351 137.720 1.00 42.62  ? 272 LEU A CB  1 
ATOM   1841  C  CG  . LEU A 1 279 ? 115.430 159.875 138.031 1.00 42.62  ? 272 LEU A CG  1 
ATOM   1842  C  CD1 . LEU A 1 279 ? 115.569 159.600 139.512 1.00 42.62  ? 272 LEU A CD1 1 
ATOM   1843  C  CD2 . LEU A 1 279 ? 115.765 158.636 137.231 1.00 42.62  ? 272 LEU A CD2 1 
ATOM   1844  N  N   . ASP A 1 280 ? 111.259 160.590 135.909 1.00 54.42  ? 273 ASP A N   1 
ATOM   1845  C  CA  . ASP A 1 280 ? 109.917 161.153 135.884 1.00 54.42  ? 273 ASP A CA  1 
ATOM   1846  C  C   . ASP A 1 280 ? 109.317 161.096 137.282 1.00 54.42  ? 273 ASP A C   1 
ATOM   1847  O  O   . ASP A 1 280 ? 109.294 160.034 137.912 1.00 54.42  ? 273 ASP A O   1 
ATOM   1848  C  CB  . ASP A 1 280 ? 109.034 160.392 134.895 1.00 54.42  ? 273 ASP A CB  1 
ATOM   1849  C  CG  . ASP A 1 280 ? 107.884 161.229 134.374 1.00 54.42  ? 273 ASP A CG  1 
ATOM   1850  O  OD1 . ASP A 1 280 ? 106.861 161.337 135.080 1.00 54.42  ? 273 ASP A OD1 1 
ATOM   1851  O  OD2 . ASP A 1 280 ? 108.001 161.774 133.257 1.00 54.42  ? 273 ASP A OD2 1 
ATOM   1852  N  N   . THR A 1 281 ? 108.839 162.238 137.766 1.00 59.75  ? 274 THR A N   1 
ATOM   1853  C  CA  . THR A 1 281 ? 108.240 162.351 139.090 1.00 59.75  ? 274 THR A CA  1 
ATOM   1854  C  C   . THR A 1 281 ? 106.897 163.059 139.009 1.00 59.75  ? 274 THR A C   1 
ATOM   1855  O  O   . THR A 1 281 ? 106.598 163.957 139.801 1.00 59.75  ? 274 THR A O   1 
ATOM   1856  C  CB  . THR A 1 281 ? 109.168 163.085 140.054 1.00 59.75  ? 274 THR A CB  1 
ATOM   1857  O  OG1 . THR A 1 281 ? 109.446 164.393 139.543 1.00 59.75  ? 274 THR A OG1 1 
ATOM   1858  C  CG2 . THR A 1 281 ? 110.474 162.326 140.225 1.00 59.75  ? 274 THR A CG2 1 
ATOM   1859  N  N   . SER A 1 282 ? 106.068 162.668 138.041 1.00 67.41  ? 275 SER A N   1 
ATOM   1860  C  CA  . SER A 1 282 ? 104.777 163.323 137.855 1.00 67.41  ? 275 SER A CA  1 
ATOM   1861  C  C   . SER A 1 282 ? 103.852 163.066 139.039 1.00 67.41  ? 275 SER A C   1 
ATOM   1862  O  O   . SER A 1 282 ? 103.268 163.997 139.604 1.00 67.41  ? 275 SER A O   1 
ATOM   1863  C  CB  . SER A 1 282 ? 104.134 162.847 136.552 1.00 67.41  ? 275 SER A CB  1 
ATOM   1864  O  OG  . SER A 1 282 ? 105.087 162.790 135.506 1.00 67.41  ? 275 SER A OG  1 
ATOM   1865  N  N   . ASN A 1 283 ? 103.704 161.802 139.427 1.00 73.66  ? 276 ASN A N   1 
ATOM   1866  C  CA  . ASN A 1 283 ? 102.798 161.423 140.502 1.00 73.66  ? 276 ASN A CA  1 
ATOM   1867  C  C   . ASN A 1 283 ? 103.596 161.314 141.795 1.00 73.66  ? 276 ASN A C   1 
ATOM   1868  O  O   . ASN A 1 283 ? 104.647 160.668 141.831 1.00 73.66  ? 276 ASN A O   1 
ATOM   1869  C  CB  . ASN A 1 283 ? 102.095 160.104 140.155 1.00 73.66  ? 276 ASN A CB  1 
ATOM   1870  C  CG  . ASN A 1 283 ? 101.261 159.528 141.304 1.00 73.66  ? 276 ASN A CG  1 
ATOM   1871  O  OD1 . ASN A 1 283 ? 101.585 159.659 142.483 1.00 73.66  ? 276 ASN A OD1 1 
ATOM   1872  N  ND2 . ASN A 1 283 ? 100.160 158.880 140.941 1.00 73.66  ? 276 ASN A ND2 1 
ATOM   1873  N  N   . LEU A 1 284 ? 103.089 161.947 142.855 1.00 78.25  ? 277 LEU A N   1 
ATOM   1874  C  CA  . LEU A 1 284 ? 103.791 161.957 144.134 1.00 78.25  ? 277 LEU A CA  1 
ATOM   1875  C  C   . LEU A 1 284 ? 103.660 160.637 144.884 1.00 78.25  ? 277 LEU A C   1 
ATOM   1876  O  O   . LEU A 1 284 ? 104.618 160.203 145.534 1.00 78.25  ? 277 LEU A O   1 
ATOM   1877  C  CB  . LEU A 1 284 ? 103.273 163.104 145.004 1.00 78.25  ? 277 LEU A CB  1 
ATOM   1878  C  CG  . LEU A 1 284 ? 103.445 164.511 144.429 1.00 78.25  ? 277 LEU A CG  1 
ATOM   1879  C  CD1 . LEU A 1 284 ? 103.056 165.562 145.456 1.00 78.25  ? 277 LEU A CD1 1 
ATOM   1880  C  CD2 . LEU A 1 284 ? 104.873 164.725 143.955 1.00 78.25  ? 277 LEU A CD2 1 
ATOM   1881  N  N   . GLU A 1 285 ? 102.492 159.992 144.816 1.00 78.47  ? 278 GLU A N   1 
ATOM   1882  C  CA  . GLU A 1 285 ? 102.300 158.728 145.522 1.00 78.47  ? 278 GLU A CA  1 
ATOM   1883  C  C   . GLU A 1 285 ? 103.244 157.655 144.997 1.00 78.47  ? 278 GLU A C   1 
ATOM   1884  O  O   . GLU A 1 285 ? 103.836 156.900 145.778 1.00 78.47  ? 278 GLU A O   1 
ATOM   1885  C  CB  . GLU A 1 285 ? 100.843 158.278 145.392 1.00 78.47  ? 278 GLU A CB  1 
ATOM   1886  C  CG  . GLU A 1 285 ? 99.839  159.171 146.107 1.00 78.47  ? 278 GLU A CG  1 
ATOM   1887  C  CD  . GLU A 1 285 ? 98.405  158.728 145.891 1.00 78.47  ? 278 GLU A CD  1 
ATOM   1888  O  OE1 . GLU A 1 285 ? 98.176  157.847 145.037 1.00 78.47  ? 278 GLU A OE1 1 
ATOM   1889  O  OE2 . GLU A 1 285 ? 97.506  159.257 146.579 1.00 78.47  ? 278 GLU A OE2 1 
ATOM   1890  N  N   . LEU A 1 286 ? 103.401 157.577 143.682 1.00 72.14  ? 279 LEU A N   1 
ATOM   1891  C  CA  . LEU A 1 286 ? 104.272 156.601 143.052 1.00 72.14  ? 279 LEU A CA  1 
ATOM   1892  C  C   . LEU A 1 286 ? 105.733 157.023 143.184 1.00 72.14  ? 279 LEU A C   1 
ATOM   1893  O  O   . LEU A 1 286 ? 106.035 158.207 143.346 1.00 72.14  ? 279 LEU A O   1 
ATOM   1894  C  CB  . LEU A 1 286 ? 103.895 156.451 141.581 1.00 72.14  ? 279 LEU A CB  1 
ATOM   1895  C  CG  . LEU A 1 286 ? 102.518 155.868 141.258 1.00 72.14  ? 279 LEU A CG  1 
ATOM   1896  C  CD1 . LEU A 1 286 ? 102.590 155.049 139.991 1.00 72.14  ? 279 LEU A CD1 1 
ATOM   1897  C  CD2 . LEU A 1 286 ? 101.995 155.009 142.401 1.00 72.14  ? 279 LEU A CD2 1 
ATOM   1898  N  N   . PRO A 1 287 ? 106.661 156.076 143.120 1.00 61.01  ? 280 PRO A N   1 
ATOM   1899  C  CA  . PRO A 1 287 ? 108.083 156.423 143.148 1.00 61.01  ? 280 PRO A CA  1 
ATOM   1900  C  C   . PRO A 1 287 ? 108.525 156.923 141.778 1.00 61.01  ? 280 PRO A C   1 
ATOM   1901  O  O   . PRO A 1 287 ? 107.766 156.924 140.812 1.00 61.01  ? 280 PRO A O   1 
ATOM   1902  C  CB  . PRO A 1 287 ? 108.777 155.109 143.522 1.00 61.01  ? 280 PRO A CB  1 
ATOM   1903  C  CG  . PRO A 1 287 ? 107.741 154.041 143.432 1.00 61.01  ? 280 PRO A CG  1 
ATOM   1904  C  CD  . PRO A 1 287 ? 106.447 154.628 142.979 1.00 61.01  ? 280 PRO A CD  1 
ATOM   1905  N  N   . GLU A 1 288 ? 109.779 157.356 141.711 1.00 55.51  ? 281 GLU A N   1 
ATOM   1906  C  CA  . GLU A 1 288 ? 110.320 157.884 140.470 1.00 55.51  ? 281 GLU A CA  1 
ATOM   1907  C  C   . GLU A 1 288 ? 110.523 156.765 139.451 1.00 55.51  ? 281 GLU A C   1 
ATOM   1908  O  O   . GLU A 1 288 ? 110.712 155.596 139.796 1.00 55.51  ? 281 GLU A O   1 
ATOM   1909  C  CB  . GLU A 1 288 ? 111.640 158.610 140.730 1.00 55.51  ? 281 GLU A CB  1 
ATOM   1910  C  CG  . GLU A 1 288 ? 112.801 157.698 141.085 1.00 55.51  ? 281 GLU A CG  1 
ATOM   1911  C  CD  . GLU A 1 288 ? 112.776 157.237 142.527 1.00 55.51  ? 281 GLU A CD  1 
ATOM   1912  O  OE1 . GLU A 1 288 ? 111.799 157.550 143.239 1.00 55.51  ? 281 GLU A OE1 1 
ATOM   1913  O  OE2 . GLU A 1 288 ? 113.736 156.562 142.951 1.00 55.51  ? 281 GLU A OE2 1 
ATOM   1914  N  N   . ALA A 1 289 ? 110.473 157.140 138.176 1.00 46.11  ? 282 ALA A N   1 
ATOM   1915  C  CA  . ALA A 1 289 ? 110.679 156.207 137.078 1.00 46.11  ? 282 ALA A CA  1 
ATOM   1916  C  C   . ALA A 1 289 ? 111.771 156.742 136.166 1.00 46.11  ? 282 ALA A C   1 
ATOM   1917  O  O   . ALA A 1 289 ? 111.728 157.907 135.759 1.00 46.11  ? 282 ALA A O   1 
ATOM   1918  C  CB  . ALA A 1 289 ? 109.388 155.988 136.289 1.00 46.11  ? 282 ALA A CB  1 
ATOM   1919  N  N   . VAL A 1 290 ? 112.743 155.893 135.848 1.00 38.73  ? 283 VAL A N   1 
ATOM   1920  C  CA  . VAL A 1 290 ? 113.862 156.288 135.001 1.00 38.73  ? 283 VAL A CA  1 
ATOM   1921  C  C   . VAL A 1 290 ? 113.420 156.254 133.544 1.00 38.73  ? 283 VAL A C   1 
ATOM   1922  O  O   . VAL A 1 290 ? 112.784 155.292 133.097 1.00 38.73  ? 283 VAL A O   1 
ATOM   1923  C  CB  . VAL A 1 290 ? 115.074 155.376 135.245 1.00 38.73  ? 283 VAL A CB  1 
ATOM   1924  C  CG1 . VAL A 1 290 ? 114.653 153.919 135.236 1.00 38.73  ? 283 VAL A CG1 1 
ATOM   1925  C  CG2 . VAL A 1 290 ? 116.156 155.633 134.214 1.00 38.73  ? 283 VAL A CG2 1 
ATOM   1926  N  N   . VAL A 1 291 ? 113.743 157.311 132.800 1.00 38.22  ? 284 VAL A N   1 
ATOM   1927  C  CA  . VAL A 1 291 ? 113.292 157.434 131.417 1.00 38.22  ? 284 VAL A CA  1 
ATOM   1928  C  C   . VAL A 1 291 ? 114.421 157.682 130.429 1.00 38.22  ? 284 VAL A C   1 
ATOM   1929  O  O   . VAL A 1 291 ? 114.220 157.506 129.214 1.00 38.22  ? 284 VAL A O   1 
ATOM   1930  C  CB  . VAL A 1 291 ? 112.225 158.546 131.300 1.00 38.22  ? 284 VAL A CB  1 
ATOM   1931  C  CG1 . VAL A 1 291 ? 112.883 159.913 131.248 1.00 38.22  ? 284 VAL A CG1 1 
ATOM   1932  C  CG2 . VAL A 1 291 ? 111.333 158.317 130.092 1.00 38.22  ? 284 VAL A CG2 1 
ATOM   1933  N  N   . PHE A 1 292 ? 115.615 158.076 130.865 1.00 37.44  ? 285 PHE A N   1 
ATOM   1934  C  CA  . PHE A 1 292 ? 116.727 158.316 129.956 1.00 37.44  ? 285 PHE A CA  1 
ATOM   1935  C  C   . PHE A 1 292 ? 118.011 158.261 130.766 1.00 37.44  ? 285 PHE A C   1 
ATOM   1936  O  O   . PHE A 1 292 ? 118.038 158.708 131.913 1.00 37.44  ? 285 PHE A O   1 
ATOM   1937  C  CB  . PHE A 1 292 ? 116.585 159.670 129.250 1.00 37.44  ? 285 PHE A CB  1 
ATOM   1938  C  CG  . PHE A 1 292 ? 117.833 160.134 128.554 1.00 37.44  ? 285 PHE A CG  1 
ATOM   1939  C  CD1 . PHE A 1 292 ? 118.166 159.644 127.304 1.00 37.44  ? 285 PHE A CD1 1 
ATOM   1940  C  CD2 . PHE A 1 292 ? 118.659 161.077 129.136 1.00 37.44  ? 285 PHE A CD2 1 
ATOM   1941  C  CE1 . PHE A 1 292 ? 119.306 160.074 126.657 1.00 37.44  ? 285 PHE A CE1 1 
ATOM   1942  C  CE2 . PHE A 1 292 ? 119.799 161.509 128.492 1.00 37.44  ? 285 PHE A CE2 1 
ATOM   1943  C  CZ  . PHE A 1 292 ? 120.123 161.006 127.251 1.00 37.44  ? 285 PHE A CZ  1 
ATOM   1944  N  N   . GLN A 1 293 ? 119.067 157.715 130.172 1.00 33.62  ? 286 GLN A N   1 
ATOM   1945  C  CA  . GLN A 1 293 ? 120.306 157.509 130.913 1.00 33.62  ? 286 GLN A CA  1 
ATOM   1946  C  C   . GLN A 1 293 ? 121.490 157.619 129.967 1.00 33.62  ? 286 GLN A C   1 
ATOM   1947  O  O   . GLN A 1 293 ? 121.668 156.764 129.096 1.00 33.62  ? 286 GLN A O   1 
ATOM   1948  C  CB  . GLN A 1 293 ? 120.294 156.149 131.610 1.00 33.62  ? 286 GLN A CB  1 
ATOM   1949  C  CG  . GLN A 1 293 ? 121.624 155.736 132.199 1.00 33.62  ? 286 GLN A CG  1 
ATOM   1950  C  CD  . GLN A 1 293 ? 121.463 154.924 133.467 1.00 33.62  ? 286 GLN A CD  1 
ATOM   1951  O  OE1 . GLN A 1 293 ? 120.392 154.907 134.072 1.00 33.62  ? 286 GLN A OE1 1 
ATOM   1952  N  NE2 . GLN A 1 293 ? 122.527 154.247 133.878 1.00 33.62  ? 286 GLN A NE2 1 
ATOM   1953  N  N   . ASP A 1 294 ? 122.296 158.661 130.143 1.00 35.72  ? 287 ASP A N   1 
ATOM   1954  C  CA  . ASP A 1 294 ? 123.520 158.839 129.381 1.00 35.72  ? 287 ASP A CA  1 
ATOM   1955  C  C   . ASP A 1 294 ? 124.707 158.681 130.320 1.00 35.72  ? 287 ASP A C   1 
ATOM   1956  O  O   . ASP A 1 294 ? 124.567 158.768 131.540 1.00 35.72  ? 287 ASP A O   1 
ATOM   1957  C  CB  . ASP A 1 294 ? 123.560 160.208 128.693 1.00 35.72  ? 287 ASP A CB  1 
ATOM   1958  C  CG  . ASP A 1 294 ? 124.597 160.275 127.591 1.00 35.72  ? 287 ASP A CG  1 
ATOM   1959  O  OD1 . ASP A 1 294 ? 125.261 159.249 127.338 1.00 35.72  ? 287 ASP A OD1 1 
ATOM   1960  O  OD2 . ASP A 1 294 ? 124.748 161.351 126.978 1.00 35.72  ? 287 ASP A OD2 1 
ATOM   1961  N  N   . SER A 1 295 ? 125.885 158.442 129.752 1.00 33.18  ? 288 SER A N   1 
ATOM   1962  C  CA  . SER A 1 295 ? 127.046 158.187 130.588 1.00 33.18  ? 288 SER A CA  1 
ATOM   1963  C  C   . SER A 1 295 ? 128.314 158.588 129.854 1.00 33.18  ? 288 SER A C   1 
ATOM   1964  O  O   . SER A 1 295 ? 128.328 158.748 128.632 1.00 33.18  ? 288 SER A O   1 
ATOM   1965  C  CB  . SER A 1 295 ? 127.119 156.715 131.008 1.00 33.18  ? 288 SER A CB  1 
ATOM   1966  O  OG  . SER A 1 295 ? 127.302 155.875 129.883 1.00 33.18  ? 288 SER A OG  1 
ATOM   1967  N  N   . VAL A 1 296 ? 129.383 158.755 130.628 1.00 28.96  ? 289 VAL A N   1 
ATOM   1968  C  CA  . VAL A 1 296 ? 130.711 159.020 130.095 1.00 28.96  ? 289 VAL A CA  1 
ATOM   1969  C  C   . VAL A 1 296 ? 131.710 158.160 130.856 1.00 28.96  ? 289 VAL A C   1 
ATOM   1970  O  O   . VAL A 1 296 ? 131.515 157.834 132.033 1.00 28.96  ? 289 VAL A O   1 
ATOM   1971  C  CB  . VAL A 1 296 ? 131.080 160.519 130.171 1.00 28.96  ? 289 VAL A CB  1 
ATOM   1972  C  CG1 . VAL A 1 296 ? 131.546 160.892 131.560 1.00 28.96  ? 289 VAL A CG1 1 
ATOM   1973  C  CG2 . VAL A 1 296 ? 132.142 160.857 129.140 1.00 28.96  ? 289 VAL A CG2 1 
ATOM   1974  N  N   . VAL A 1 297 ? 132.776 157.770 130.162 1.00 29.47  ? 290 VAL A N   1 
ATOM   1975  C  CA  . VAL A 1 297 ? 133.786 156.860 130.687 1.00 29.47  ? 290 VAL A CA  1 
ATOM   1976  C  C   . VAL A 1 297 ? 135.127 157.575 130.692 1.00 29.47  ? 290 VAL A C   1 
ATOM   1977  O  O   . VAL A 1 297 ? 135.552 158.116 129.665 1.00 29.47  ? 290 VAL A O   1 
ATOM   1978  C  CB  . VAL A 1 297 ? 133.866 155.564 129.861 1.00 29.47  ? 290 VAL A CB  1 
ATOM   1979  C  CG1 . VAL A 1 297 ? 134.839 154.593 130.497 1.00 29.47  ? 290 VAL A CG1 1 
ATOM   1980  C  CG2 . VAL A 1 297 ? 132.494 154.935 129.736 1.00 29.47  ? 290 VAL A CG2 1 
ATOM   1981  N  N   . PHE A 1 298 ? 135.792 157.565 131.842 1.00 28.45  ? 291 PHE A N   1 
ATOM   1982  C  CA  . PHE A 1 298 ? 137.085 158.195 132.035 1.00 28.45  ? 291 PHE A CA  1 
ATOM   1983  C  C   . PHE A 1 298 ? 138.128 157.131 132.339 1.00 28.45  ? 291 PHE A C   1 
ATOM   1984  O  O   . PHE A 1 298 ? 137.820 156.091 132.929 1.00 28.45  ? 291 PHE A O   1 
ATOM   1985  C  CB  . PHE A 1 298 ? 137.058 159.180 133.199 1.00 28.45  ? 291 PHE A CB  1 
ATOM   1986  C  CG  . PHE A 1 298 ? 136.161 160.364 132.994 1.00 28.45  ? 291 PHE A CG  1 
ATOM   1987  C  CD1 . PHE A 1 298 ? 136.439 161.304 132.022 1.00 28.45  ? 291 PHE A CD1 1 
ATOM   1988  C  CD2 . PHE A 1 298 ? 135.077 160.572 133.823 1.00 28.45  ? 291 PHE A CD2 1 
ATOM   1989  C  CE1 . PHE A 1 298 ? 135.628 162.407 131.854 1.00 28.45  ? 291 PHE A CE1 1 
ATOM   1990  C  CE2 . PHE A 1 298 ? 134.265 161.672 133.659 1.00 28.45  ? 291 PHE A CE2 1 
ATOM   1991  C  CZ  . PHE A 1 298 ? 134.541 162.589 132.673 1.00 28.45  ? 291 PHE A CZ  1 
ATOM   1992  N  N   . ARG A 1 299 ? 139.372 157.406 131.960 1.00 28.02  ? 292 ARG A N   1 
ATOM   1993  C  CA  . ARG A 1 299 ? 140.495 156.571 132.359 1.00 28.02  ? 292 ARG A CA  1 
ATOM   1994  C  C   . ARG A 1 299 ? 141.437 157.363 133.251 1.00 28.02  ? 292 ARG A C   1 
ATOM   1995  O  O   . ARG A 1 299 ? 141.754 158.520 132.963 1.00 28.02  ? 292 ARG A O   1 
ATOM   1996  C  CB  . ARG A 1 299 ? 141.262 156.032 131.155 1.00 28.02  ? 292 ARG A CB  1 
ATOM   1997  C  CG  . ARG A 1 299 ? 142.465 155.188 131.544 1.00 28.02  ? 292 ARG A CG  1 
ATOM   1998  C  CD  . ARG A 1 299 ? 143.015 154.420 130.361 1.00 28.02  ? 292 ARG A CD  1 
ATOM   1999  N  NE  . ARG A 1 299 ? 142.203 153.249 130.056 1.00 28.02  ? 292 ARG A NE  1 
ATOM   2000  C  CZ  . ARG A 1 299 ? 142.187 152.137 130.779 1.00 28.02  ? 292 ARG A CZ  1 
ATOM   2001  N  NH1 . ARG A 1 299 ? 142.944 152.001 131.854 1.00 28.02  ? 292 ARG A NH1 1 
ATOM   2002  N  NH2 . ARG A 1 299 ? 141.394 151.136 130.410 1.00 28.02  ? 292 ARG A NH2 1 
ATOM   2003  N  N   . VAL A 1 300 ? 141.869 156.741 134.342 1.00 24.71  ? 293 VAL A N   1 
ATOM   2004  C  CA  . VAL A 1 300 ? 142.829 157.361 135.246 1.00 24.71  ? 293 VAL A CA  1 
ATOM   2005  C  C   . VAL A 1 300 ? 144.212 157.296 134.613 1.00 24.71  ? 293 VAL A C   1 
ATOM   2006  O  O   . VAL A 1 300 ? 144.660 156.227 134.182 1.00 24.71  ? 293 VAL A O   1 
ATOM   2007  C  CB  . VAL A 1 300 ? 142.809 156.669 136.616 1.00 24.71  ? 293 VAL A CB  1 
ATOM   2008  C  CG1 . VAL A 1 300 ? 143.838 157.288 137.533 1.00 24.71  ? 293 VAL A CG1 1 
ATOM   2009  C  CG2 . VAL A 1 300 ? 141.426 156.762 137.231 1.00 24.71  ? 293 VAL A CG2 1 
ATOM   2010  N  N   . ALA A 1 301 ? 144.889 158.437 134.555 1.00 23.21  ? 294 ALA A N   1 
ATOM   2011  C  CA  . ALA A 1 301 ? 146.173 158.510 133.875 1.00 23.21  ? 294 ALA A CA  1 
ATOM   2012  C  C   . ALA A 1 301 ? 147.199 157.630 134.580 1.00 23.21  ? 294 ALA A C   1 
ATOM   2013  O  O   . ALA A 1 301 ? 147.373 157.744 135.800 1.00 23.21  ? 294 ALA A O   1 
ATOM   2014  C  CB  . ALA A 1 301 ? 146.665 159.954 133.825 1.00 23.21  ? 294 ALA A CB  1 
ATOM   2015  N  N   . PRO A 1 302 ? 147.892 156.753 133.863 1.00 24.16  ? 295 PRO A N   1 
ATOM   2016  C  CA  . PRO A 1 302 ? 148.867 155.872 134.506 1.00 24.16  ? 295 PRO A CA  1 
ATOM   2017  C  C   . PRO A 1 302 ? 150.175 156.589 134.797 1.00 24.16  ? 295 PRO A C   1 
ATOM   2018  O  O   . PRO A 1 302 ? 150.467 157.660 134.264 1.00 24.16  ? 295 PRO A O   1 
ATOM   2019  C  CB  . PRO A 1 302 ? 149.070 154.767 133.467 1.00 24.16  ? 295 PRO A CB  1 
ATOM   2020  C  CG  . PRO A 1 302 ? 148.865 155.458 132.174 1.00 24.16  ? 295 PRO A CG  1 
ATOM   2021  C  CD  . PRO A 1 302 ? 147.813 156.515 132.413 1.00 24.16  ? 295 PRO A CD  1 
ATOM   2022  N  N   . TRP A 1 303 ? 150.972 155.964 135.659 1.00 25.34  ? 296 TRP A N   1 
ATOM   2023  C  CA  . TRP A 1 303 ? 152.290 156.483 136.000 1.00 25.34  ? 296 TRP A CA  1 
ATOM   2024  C  C   . TRP A 1 303 ? 153.290 156.054 134.935 1.00 25.34  ? 296 TRP A C   1 
ATOM   2025  O  O   . TRP A 1 303 ? 153.509 154.857 134.727 1.00 25.34  ? 296 TRP A O   1 
ATOM   2026  C  CB  . TRP A 1 303 ? 152.716 155.985 137.376 1.00 25.34  ? 296 TRP A CB  1 
ATOM   2027  C  CG  . TRP A 1 303 ? 153.978 156.601 137.874 1.00 25.34  ? 296 TRP A CG  1 
ATOM   2028  C  CD1 . TRP A 1 303 ? 154.158 157.890 138.265 1.00 25.34  ? 296 TRP A CD1 1 
ATOM   2029  C  CD2 . TRP A 1 303 ? 155.239 155.948 138.048 1.00 25.34  ? 296 TRP A CD2 1 
ATOM   2030  N  NE1 . TRP A 1 303 ? 155.455 158.086 138.668 1.00 25.34  ? 296 TRP A NE1 1 
ATOM   2031  C  CE2 . TRP A 1 303 ? 156.139 156.907 138.546 1.00 25.34  ? 296 TRP A CE2 1 
ATOM   2032  C  CE3 . TRP A 1 303 ? 155.694 154.646 137.832 1.00 25.34  ? 296 TRP A CE3 1 
ATOM   2033  C  CZ2 . TRP A 1 303 ? 157.465 156.608 138.828 1.00 25.34  ? 296 TRP A CZ2 1 
ATOM   2034  C  CZ3 . TRP A 1 303 ? 157.009 154.350 138.115 1.00 25.34  ? 296 TRP A CZ3 1 
ATOM   2035  C  CH2 . TRP A 1 303 ? 157.881 155.327 138.607 1.00 25.34  ? 296 TRP A CH2 1 
ATOM   2036  N  N   . ILE A 1 304 ? 153.900 157.027 134.266 1.00 24.36  ? 297 ILE A N   1 
ATOM   2037  C  CA  . ILE A 1 304 ? 154.775 156.782 133.128 1.00 24.36  ? 297 ILE A CA  1 
ATOM   2038  C  C   . ILE A 1 304 ? 156.175 157.258 133.486 1.00 24.36  ? 297 ILE A C   1 
ATOM   2039  O  O   . ILE A 1 304 ? 156.352 158.394 133.939 1.00 24.36  ? 297 ILE A O   1 
ATOM   2040  C  CB  . ILE A 1 304 ? 154.263 157.491 131.864 1.00 24.36  ? 297 ILE A CB  1 
ATOM   2041  C  CG1 . ILE A 1 304 ? 152.748 157.345 131.759 1.00 24.36  ? 297 ILE A CG1 1 
ATOM   2042  C  CG2 . ILE A 1 304 ? 154.925 156.917 130.632 1.00 24.36  ? 297 ILE A CG2 1 
ATOM   2043  C  CD1 . ILE A 1 304 ? 152.146 158.107 130.613 1.00 24.36  ? 297 ILE A CD1 1 
ATOM   2044  N  N   . MET A 1 305 ? 157.161 156.394 133.281 1.00 27.79  ? 298 MET A N   1 
ATOM   2045  C  CA  . MET A 1 305 ? 158.545 156.703 133.596 1.00 27.79  ? 298 MET A CA  1 
ATOM   2046  C  C   . MET A 1 305 ? 159.219 157.404 132.421 1.00 27.79  ? 298 MET A C   1 
ATOM   2047  O  O   . MET A 1 305 ? 158.634 157.586 131.352 1.00 27.79  ? 298 MET A O   1 
ATOM   2048  C  CB  . MET A 1 305 ? 159.300 155.429 133.956 1.00 27.79  ? 298 MET A CB  1 
ATOM   2049  C  CG  . MET A 1 305 ? 158.875 154.802 135.263 1.00 27.79  ? 298 MET A CG  1 
ATOM   2050  S  SD  . MET A 1 305 ? 160.171 153.801 136.007 1.00 27.79  ? 298 MET A SD  1 
ATOM   2051  C  CE  . MET A 1 305 ? 161.563 154.914 135.881 1.00 27.79  ? 298 MET A CE  1 
ATOM   2052  N  N   . THR A 1 306 ? 160.472 157.805 132.631 1.00 26.99  ? 299 THR A N   1 
ATOM   2053  C  CA  . THR A 1 306 ? 161.268 158.440 131.591 1.00 26.99  ? 299 THR A CA  1 
ATOM   2054  C  C   . THR A 1 306 ? 162.609 157.723 131.481 1.00 26.99  ? 299 THR A C   1 
ATOM   2055  O  O   . THR A 1 306 ? 163.316 157.571 132.491 1.00 26.99  ? 299 THR A O   1 
ATOM   2056  C  CB  . THR A 1 306 ? 161.487 159.930 131.879 1.00 26.99  ? 299 THR A CB  1 
ATOM   2057  O  OG1 . THR A 1 306 ? 162.294 160.082 133.052 1.00 26.99  ? 299 THR A OG1 1 
ATOM   2058  C  CG2 . THR A 1 306 ? 160.163 160.638 132.081 1.00 26.99  ? 299 THR A CG2 1 
ATOM   2059  N  N   . PRO A 1 307 ? 162.997 157.277 130.289 1.00 29.14  ? 300 PRO A N   1 
ATOM   2060  C  CA  . PRO A 1 307 ? 164.289 156.597 130.134 1.00 29.14  ? 300 PRO A CA  1 
ATOM   2061  C  C   . PRO A 1 307 ? 165.458 157.564 130.134 1.00 29.14  ? 300 PRO A C   1 
ATOM   2062  O  O   . PRO A 1 307 ? 165.282 158.758 130.389 1.00 29.14  ? 300 PRO A O   1 
ATOM   2063  C  CB  . PRO A 1 307 ? 164.145 155.889 128.784 1.00 29.14  ? 300 PRO A CB  1 
ATOM   2064  C  CG  . PRO A 1 307 ? 163.211 156.755 128.025 1.00 29.14  ? 300 PRO A CG  1 
ATOM   2065  C  CD  . PRO A 1 307 ? 162.244 157.326 129.027 1.00 29.14  ? 300 PRO A CD  1 
ATOM   2066  N  N   . ASN A 1 308 ? 166.658 157.061 129.847 1.00 33.88  ? 301 ASN A N   1 
ATOM   2067  C  CA  . ASN A 1 308 ? 167.863 157.877 129.907 1.00 33.88  ? 301 ASN A CA  1 
ATOM   2068  C  C   . ASN A 1 308 ? 168.116 158.690 128.644 1.00 33.88  ? 301 ASN A C   1 
ATOM   2069  O  O   . ASN A 1 308 ? 169.039 159.511 128.637 1.00 33.88  ? 301 ASN A O   1 
ATOM   2070  C  CB  . ASN A 1 308 ? 169.079 156.994 130.189 1.00 33.88  ? 301 ASN A CB  1 
ATOM   2071  C  CG  . ASN A 1 308 ? 168.976 156.272 131.512 1.00 33.88  ? 301 ASN A CG  1 
ATOM   2072  O  OD1 . ASN A 1 308 ? 168.093 155.439 131.711 1.00 33.88  ? 301 ASN A OD1 1 
ATOM   2073  N  ND2 . ASN A 1 308 ? 169.881 156.589 132.430 1.00 33.88  ? 301 ASN A ND2 1 
ATOM   2074  N  N   . THR A 1 309 ? 167.336 158.495 127.586 1.00 34.81  ? 302 THR A N   1 
ATOM   2075  C  CA  . THR A 1 309 ? 167.565 159.208 126.337 1.00 34.81  ? 302 THR A CA  1 
ATOM   2076  C  C   . THR A 1 309 ? 166.839 160.545 126.266 1.00 34.81  ? 302 THR A C   1 
ATOM   2077  O  O   . THR A 1 309 ? 167.019 161.276 125.287 1.00 34.81  ? 302 THR A O   1 
ATOM   2078  C  CB  . THR A 1 309 ? 167.151 158.340 125.148 1.00 34.81  ? 302 THR A CB  1 
ATOM   2079  O  OG1 . THR A 1 309 ? 165.772 157.978 125.278 1.00 34.81  ? 302 THR A OG1 1 
ATOM   2080  C  CG2 . THR A 1 309 ? 167.996 157.083 125.098 1.00 34.81  ? 302 THR A CG2 1 
ATOM   2081  N  N   . GLN A 1 310 ? 166.028 160.886 127.273 1.00 32.01  ? 303 GLN A N   1 
ATOM   2082  C  CA  . GLN A 1 310 ? 165.328 162.161 127.285 1.00 32.01  ? 303 GLN A CA  1 
ATOM   2083  C  C   . GLN A 1 310 ? 166.227 163.264 127.835 1.00 32.01  ? 303 GLN A C   1 
ATOM   2084  O  O   . GLN A 1 310 ? 167.070 163.011 128.702 1.00 32.01  ? 303 GLN A O   1 
ATOM   2085  C  CB  . GLN A 1 310 ? 164.065 162.063 128.132 1.00 32.01  ? 303 GLN A CB  1 
ATOM   2086  C  CG  . GLN A 1 310 ? 163.067 161.055 127.615 1.00 32.01  ? 303 GLN A CG  1 
ATOM   2087  C  CD  . GLN A 1 310 ? 162.189 161.623 126.529 1.00 32.01  ? 303 GLN A CD  1 
ATOM   2088  O  OE1 . GLN A 1 310 ? 162.333 161.283 125.356 1.00 32.01  ? 303 GLN A OE1 1 
ATOM   2089  N  NE2 . GLN A 1 310 ? 161.262 162.491 126.913 1.00 32.01  ? 303 GLN A NE2 1 
ATOM   2090  N  N   . PRO A 1 311 ? 166.079 164.490 127.343 1.00 35.02  ? 304 PRO A N   1 
ATOM   2091  C  CA  . PRO A 1 311 ? 166.883 165.604 127.858 1.00 35.02  ? 304 PRO A CA  1 
ATOM   2092  C  C   . PRO A 1 311 ? 166.579 165.867 129.322 1.00 35.02  ? 304 PRO A C   1 
ATOM   2093  O  O   . PRO A 1 311 ? 165.414 165.815 129.743 1.00 35.02  ? 304 PRO A O   1 
ATOM   2094  C  CB  . PRO A 1 311 ? 166.451 166.787 126.978 1.00 35.02  ? 304 PRO A CB  1 
ATOM   2095  C  CG  . PRO A 1 311 ? 165.880 166.156 125.748 1.00 35.02  ? 304 PRO A CG  1 
ATOM   2096  C  CD  . PRO A 1 311 ? 165.216 164.906 126.226 1.00 35.02  ? 304 PRO A CD  1 
ATOM   2097  N  N   . PRO A 1 312 ? 167.596 166.152 130.127 1.00 37.48  ? 305 PRO A N   1 
ATOM   2098  C  CA  . PRO A 1 312 ? 167.371 166.419 131.549 1.00 37.48  ? 305 PRO A CA  1 
ATOM   2099  C  C   . PRO A 1 312 ? 166.769 167.797 131.778 1.00 37.48  ? 305 PRO A C   1 
ATOM   2100  O  O   . PRO A 1 312 ? 166.808 168.677 130.918 1.00 37.48  ? 305 PRO A O   1 
ATOM   2101  C  CB  . PRO A 1 312 ? 168.780 166.334 132.150 1.00 37.48  ? 305 PRO A CB  1 
ATOM   2102  C  CG  . PRO A 1 312 ? 169.589 165.602 131.122 1.00 37.48  ? 305 PRO A CG  1 
ATOM   2103  C  CD  . PRO A 1 312 ? 169.028 166.052 129.820 1.00 37.48  ? 305 PRO A CD  1 
ATOM   2104  N  N   . GLN A 1 313 ? 166.197 167.969 132.970 1.00 38.53  ? 306 GLN A N   1 
ATOM   2105  C  CA  . GLN A 1 313 ? 165.644 169.260 133.357 1.00 38.53  ? 306 GLN A CA  1 
ATOM   2106  C  C   . GLN A 1 313 ? 166.075 169.665 134.761 1.00 38.53  ? 306 GLN A C   1 
ATOM   2107  O  O   . GLN A 1 313 ? 166.131 170.857 135.076 1.00 38.53  ? 306 GLN A O   1 
ATOM   2108  C  CB  . GLN A 1 313 ? 164.118 169.236 133.264 1.00 38.53  ? 306 GLN A CB  1 
ATOM   2109  C  CG  . GLN A 1 313 ? 163.580 169.582 131.889 1.00 38.53  ? 306 GLN A CG  1 
ATOM   2110  C  CD  . GLN A 1 313 ? 162.069 169.552 131.831 1.00 38.53  ? 306 GLN A CD  1 
ATOM   2111  O  OE1 . GLN A 1 313 ? 161.408 169.157 132.789 1.00 38.53  ? 306 GLN A OE1 1 
ATOM   2112  N  NE2 . GLN A 1 313 ? 161.513 169.975 130.704 1.00 38.53  ? 306 GLN A NE2 1 
ATOM   2113  N  N   . GLU A 1 314 ? 166.380 168.688 135.611 1.00 43.38  ? 307 GLU A N   1 
ATOM   2114  C  CA  . GLU A 1 314 ? 166.698 168.965 137.005 1.00 43.38  ? 307 GLU A CA  1 
ATOM   2115  C  C   . GLU A 1 314 ? 167.452 167.777 137.582 1.00 43.38  ? 307 GLU A C   1 
ATOM   2116  O  O   . GLU A 1 314 ? 167.096 166.627 137.317 1.00 43.38  ? 307 GLU A O   1 
ATOM   2117  C  CB  . GLU A 1 314 ? 165.423 169.241 137.810 1.00 43.38  ? 307 GLU A CB  1 
ATOM   2118  C  CG  . GLU A 1 314 ? 165.619 169.319 139.312 1.00 43.38  ? 307 GLU A CG  1 
ATOM   2119  C  CD  . GLU A 1 314 ? 164.361 169.758 140.036 1.00 43.38  ? 307 GLU A CD  1 
ATOM   2120  O  OE1 . GLU A 1 314 ? 163.360 170.066 139.357 1.00 43.38  ? 307 GLU A OE1 1 
ATOM   2121  O  OE2 . GLU A 1 314 ? 164.372 169.793 141.283 1.00 43.38  ? 307 GLU A OE2 1 
ATOM   2122  N  N   . VAL A 1 315 ? 168.486 168.060 138.370 1.00 44.97  ? 308 VAL A N   1 
ATOM   2123  C  CA  . VAL A 1 315 ? 169.359 167.036 138.930 1.00 44.97  ? 308 VAL A CA  1 
ATOM   2124  C  C   . VAL A 1 315 ? 169.359 167.167 140.445 1.00 44.97  ? 308 VAL A C   1 
ATOM   2125  O  O   . VAL A 1 315 ? 169.525 168.270 140.977 1.00 44.97  ? 308 VAL A O   1 
ATOM   2126  C  CB  . VAL A 1 315 ? 170.791 167.149 138.378 1.00 44.97  ? 308 VAL A CB  1 
ATOM   2127  C  CG1 . VAL A 1 315 ? 171.652 166.018 138.904 1.00 44.97  ? 308 VAL A CG1 1 
ATOM   2128  C  CG2 . VAL A 1 315 ? 170.774 167.142 136.863 1.00 44.97  ? 308 VAL A CG2 1 
ATOM   2129  N  N   . TYR A 1 316 ? 169.178 166.044 141.134 1.00 49.21  ? 309 TYR A N   1 
ATOM   2130  C  CA  . TYR A 1 316 ? 169.248 165.979 142.587 1.00 49.21  ? 309 TYR A CA  1 
ATOM   2131  C  C   . TYR A 1 316 ? 170.558 165.330 143.006 1.00 49.21  ? 309 TYR A C   1 
ATOM   2132  O  O   . TYR A 1 316 ? 171.121 164.516 142.269 1.00 49.21  ? 309 TYR A O   1 
ATOM   2133  C  CB  . TYR A 1 316 ? 168.072 165.191 143.168 1.00 49.21  ? 309 TYR A CB  1 
ATOM   2134  C  CG  . TYR A 1 316 ? 166.717 165.752 142.815 1.00 49.21  ? 309 TYR A CG  1 
ATOM   2135  C  CD1 . TYR A 1 316 ? 166.031 165.310 141.696 1.00 49.21  ? 309 TYR A CD1 1 
ATOM   2136  C  CD2 . TYR A 1 316 ? 166.126 166.727 143.601 1.00 49.21  ? 309 TYR A CD2 1 
ATOM   2137  C  CE1 . TYR A 1 316 ? 164.794 165.822 141.371 1.00 49.21  ? 309 TYR A CE1 1 
ATOM   2138  C  CE2 . TYR A 1 316 ? 164.890 167.246 143.284 1.00 49.21  ? 309 TYR A CE2 1 
ATOM   2139  C  CZ  . TYR A 1 316 ? 164.229 166.790 142.168 1.00 49.21  ? 309 TYR A CZ  1 
ATOM   2140  O  OH  . TYR A 1 316 ? 162.996 167.306 141.848 1.00 49.21  ? 309 TYR A OH  1 
ATOM   2141  N  N   . ALA A 1 317 ? 171.043 165.694 144.191 1.00 64.24  ? 310 ALA A N   1 
ATOM   2142  C  CA  . ALA A 1 317 ? 172.288 165.154 144.716 1.00 64.24  ? 310 ALA A CA  1 
ATOM   2143  C  C   . ALA A 1 317 ? 172.239 165.179 146.237 1.00 64.24  ? 310 ALA A C   1 
ATOM   2144  O  O   . ALA A 1 317 ? 171.198 165.445 146.844 1.00 64.24  ? 310 ALA A O   1 
ATOM   2145  C  CB  . ALA A 1 317 ? 173.497 165.934 144.189 1.00 64.24  ? 310 ALA A CB  1 
ATOM   2146  N  N   . CYS A 1 318 ? 173.382 164.898 146.856 1.00 81.01  ? 311 CYS A N   1 
ATOM   2147  C  CA  . CYS A 1 318 ? 173.502 164.859 148.305 1.00 81.01  ? 311 CYS A CA  1 
ATOM   2148  C  C   . CYS A 1 318 ? 174.867 165.375 148.729 1.00 81.01  ? 311 CYS A C   1 
ATOM   2149  O  O   . CYS A 1 318 ? 175.810 165.392 147.934 1.00 81.01  ? 311 CYS A O   1 
ATOM   2150  C  CB  . CYS A 1 318 ? 173.301 163.442 148.840 1.00 81.01  ? 311 CYS A CB  1 
ATOM   2151  S  SG  . CYS A 1 318 ? 173.889 163.217 150.528 1.00 81.01  ? 311 CYS A SG  1 
ATOM   2152  N  N   . SER A 1 319 ? 174.961 165.802 149.986 1.00 85.33  ? 312 SER A N   1 
ATOM   2153  C  CA  . SER A 1 319 ? 176.211 166.253 150.587 1.00 85.33  ? 312 SER A CA  1 
ATOM   2154  C  C   . SER A 1 319 ? 176.296 165.689 151.997 1.00 85.33  ? 312 SER A C   1 
ATOM   2155  O  O   . SER A 1 319 ? 175.417 165.950 152.825 1.00 85.33  ? 312 SER A O   1 
ATOM   2156  C  CB  . SER A 1 319 ? 176.289 167.780 150.610 1.00 85.33  ? 312 SER A CB  1 
ATOM   2157  O  OG  . SER A 1 319 ? 177.438 168.222 151.310 1.00 85.33  ? 312 SER A OG  1 
ATOM   2158  N  N   . ILE A 1 320 ? 177.346 164.917 152.294 1.00 87.29  ? 313 ILE A N   1 
ATOM   2159  C  CA  . ILE A 1 320 ? 177.457 164.298 153.653 1.00 87.29  ? 313 ILE A CA  1 
ATOM   2160  C  C   . ILE A 1 320 ? 178.793 164.696 154.302 1.00 87.29  ? 313 ILE A C   1 
ATOM   2161  O  O   . ILE A 1 320 ? 178.742 165.316 155.384 1.00 87.29  ? 313 ILE A O   1 
ATOM   2162  C  CB  . ILE A 1 320 ? 177.215 162.770 153.630 1.00 87.29  ? 313 ILE A CB  1 
ATOM   2163  C  CG1 . ILE A 1 320 ? 177.192 162.182 155.044 1.00 87.29  ? 313 ILE A CG1 1 
ATOM   2164  C  CG2 . ILE A 1 320 ? 178.207 162.036 152.740 1.00 87.29  ? 313 ILE A CG2 1 
ATOM   2165  C  CD1 . ILE A 1 320 ? 177.114 160.674 155.075 1.00 87.29  ? 313 ILE A CD1 1 
ATOM   2166  N  N   . PHE A 1 321 ? 179.929 164.384 153.667 1.00 95.80  ? 314 PHE A N   1 
ATOM   2167  C  CA  . PHE A 1 321 ? 181.236 164.704 154.221 1.00 95.80  ? 314 PHE A CA  1 
ATOM   2168  C  C   . PHE A 1 321 ? 182.269 164.280 153.186 1.00 95.80  ? 314 PHE A C   1 
ATOM   2169  O  O   . PHE A 1 321 ? 182.047 163.320 152.442 1.00 95.80  ? 314 PHE A O   1 
ATOM   2170  C  CB  . PHE A 1 321 ? 181.462 163.991 155.563 1.00 95.80  ? 314 PHE A CB  1 
ATOM   2171  C  CG  . PHE A 1 321 ? 182.387 164.721 156.500 1.00 95.80  ? 314 PHE A CG  1 
ATOM   2172  C  CD1 . PHE A 1 321 ? 183.752 164.756 156.283 1.00 95.80  ? 314 PHE A CD1 1 
ATOM   2173  C  CD2 . PHE A 1 321 ? 181.876 165.380 157.607 1.00 95.80  ? 314 PHE A CD2 1 
ATOM   2174  C  CE1 . PHE A 1 321 ? 184.591 165.429 157.150 1.00 95.80  ? 314 PHE A CE1 1 
ATOM   2175  C  CE2 . PHE A 1 321 ? 182.709 166.055 158.477 1.00 95.80  ? 314 PHE A CE2 1 
ATOM   2176  C  CZ  . PHE A 1 321 ? 184.069 166.080 158.248 1.00 95.80  ? 314 PHE A CZ  1 
ATOM   2177  N  N   . GLU A 1 322 ? 183.407 164.979 153.170 1.00 98.38  ? 315 GLU A N   1 
ATOM   2178  C  CA  . GLU A 1 322 ? 184.337 164.974 152.040 1.00 98.38  ? 315 GLU A CA  1 
ATOM   2179  C  C   . GLU A 1 322 ? 183.583 164.882 150.716 1.00 98.38  ? 315 GLU A C   1 
ATOM   2180  O  O   . GLU A 1 322 ? 183.803 163.949 149.937 1.00 98.38  ? 315 GLU A O   1 
ATOM   2181  C  CB  . GLU A 1 322 ? 185.412 163.864 152.085 1.00 98.38  ? 315 GLU A CB  1 
ATOM   2182  C  CG  . GLU A 1 322 ? 186.082 163.437 153.417 1.00 98.38  ? 315 GLU A CG  1 
ATOM   2183  C  CD  . GLU A 1 322 ? 185.232 162.632 154.387 1.00 98.38  ? 315 GLU A CD  1 
ATOM   2184  O  OE1 . GLU A 1 322 ? 185.826 161.998 155.284 1.00 98.38  ? 315 GLU A OE1 1 
ATOM   2185  O  OE2 . GLU A 1 322 ? 184.008 162.541 154.227 1.00 98.38  ? 315 GLU A OE2 1 
ATOM   2186  N  N   . ASN A 1 323 ? 182.688 165.836 150.455 1.00 92.21  ? 316 ASN A N   1 
ATOM   2187  C  CA  . ASN A 1 323 ? 181.884 165.834 149.240 1.00 92.21  ? 316 ASN A CA  1 
ATOM   2188  C  C   . ASN A 1 323 ? 182.047 167.110 148.420 1.00 92.21  ? 316 ASN A C   1 
ATOM   2189  O  O   . ASN A 1 323 ? 181.286 167.329 147.474 1.00 92.21  ? 316 ASN A O   1 
ATOM   2190  C  CB  . ASN A 1 323 ? 180.409 165.617 149.579 1.00 92.21  ? 316 ASN A CB  1 
ATOM   2191  C  CG  . ASN A 1 323 ? 180.120 164.206 150.041 1.00 92.21  ? 316 ASN A CG  1 
ATOM   2192  O  OD1 . ASN A 1 323 ? 179.135 163.958 150.734 1.00 92.21  ? 316 ASN A OD1 1 
ATOM   2193  N  ND2 . ASN A 1 323 ? 180.986 163.272 149.664 1.00 92.21  ? 316 ASN A ND2 1 
ATOM   2194  N  N   . GLU A 1 324 ? 183.019 167.959 148.763 1.00 93.64  ? 317 GLU A N   1 
ATOM   2195  C  CA  . GLU A 1 324 ? 183.208 169.191 148.004 1.00 93.64  ? 317 GLU A CA  1 
ATOM   2196  C  C   . GLU A 1 324 ? 183.607 168.902 146.562 1.00 93.64  ? 317 GLU A C   1 
ATOM   2197  O  O   . GLU A 1 324 ? 183.088 169.531 145.634 1.00 93.64  ? 317 GLU A O   1 
ATOM   2198  C  CB  . GLU A 1 324 ? 184.248 170.093 148.676 1.00 93.64  ? 317 GLU A CB  1 
ATOM   2199  C  CG  . GLU A 1 324 ? 183.853 170.679 150.032 1.00 93.64  ? 317 GLU A CG  1 
ATOM   2200  C  CD  . GLU A 1 324 ? 184.950 171.503 150.679 1.00 93.64  ? 317 GLU A CD  1 
ATOM   2201  O  OE1 . GLU A 1 324 ? 186.091 171.474 150.175 1.00 93.64  ? 317 GLU A OE1 1 
ATOM   2202  O  OE2 . GLU A 1 324 ? 184.666 172.186 151.683 1.00 93.64  ? 317 GLU A OE2 1 
ATOM   2203  N  N   . ASP A 1 325 ? 184.520 167.952 146.350 1.00 88.81  ? 318 ASP A N   1 
ATOM   2204  C  CA  . ASP A 1 325 ? 184.956 167.643 144.991 1.00 88.81  ? 318 ASP A CA  1 
ATOM   2205  C  C   . ASP A 1 325 ? 183.846 166.974 144.189 1.00 88.81  ? 318 ASP A C   1 
ATOM   2206  O  O   . ASP A 1 325 ? 183.610 167.330 143.027 1.00 88.81  ? 318 ASP A O   1 
ATOM   2207  C  CB  . ASP A 1 325 ? 186.200 166.757 145.030 1.00 88.81  ? 318 ASP A CB  1 
ATOM   2208  C  CG  . ASP A 1 325 ? 186.140 165.721 146.132 1.00 88.81  ? 318 ASP A CG  1 
ATOM   2209  O  OD1 . ASP A 1 325 ? 187.038 165.722 147.000 1.00 88.81  ? 318 ASP A OD1 1 
ATOM   2210  O  OD2 . ASP A 1 325 ? 185.194 164.906 146.130 1.00 88.81  ? 318 ASP A OD2 1 
ATOM   2211  N  N   . PHE A 1 326 ? 183.157 166.002 144.789 1.00 83.41  ? 319 PHE A N   1 
ATOM   2212  C  CA  . PHE A 1 326 ? 182.070 165.318 144.096 1.00 83.41  ? 319 PHE A CA  1 
ATOM   2213  C  C   . PHE A 1 326 ? 180.951 166.290 143.745 1.00 83.41  ? 319 PHE A C   1 
ATOM   2214  O  O   . PHE A 1 326 ? 180.453 166.305 142.611 1.00 83.41  ? 319 PHE A O   1 
ATOM   2215  C  CB  . PHE A 1 326 ? 181.550 164.174 144.969 1.00 83.41  ? 319 PHE A CB  1 
ATOM   2216  C  CG  . PHE A 1 326 ? 180.461 163.358 144.333 1.00 83.41  ? 319 PHE A CG  1 
ATOM   2217  C  CD1 . PHE A 1 326 ? 179.131 163.712 144.481 1.00 83.41  ? 319 PHE A CD1 1 
ATOM   2218  C  CD2 . PHE A 1 326 ? 180.768 162.228 143.597 1.00 83.41  ? 319 PHE A CD2 1 
ATOM   2219  C  CE1 . PHE A 1 326 ? 178.131 162.960 143.902 1.00 83.41  ? 319 PHE A CE1 1 
ATOM   2220  C  CE2 . PHE A 1 326 ? 179.771 161.473 143.016 1.00 83.41  ? 319 PHE A CE2 1 
ATOM   2221  C  CZ  . PHE A 1 326 ? 178.452 161.840 143.169 1.00 83.41  ? 319 PHE A CZ  1 
ATOM   2222  N  N   . LEU A 1 327 ? 180.552 167.122 144.708 1.00 83.00  ? 320 LEU A N   1 
ATOM   2223  C  CA  . LEU A 1 327 ? 179.494 168.089 144.448 1.00 83.00  ? 320 LEU A CA  1 
ATOM   2224  C  C   . LEU A 1 327 ? 179.930 169.118 143.414 1.00 83.00  ? 320 LEU A C   1 
ATOM   2225  O  O   . LEU A 1 327 ? 179.132 169.527 142.569 1.00 83.00  ? 320 LEU A O   1 
ATOM   2226  C  CB  . LEU A 1 327 ? 179.070 168.775 145.745 1.00 83.00  ? 320 LEU A CB  1 
ATOM   2227  C  CG  . LEU A 1 327 ? 178.010 169.869 145.596 1.00 83.00  ? 320 LEU A CG  1 
ATOM   2228  C  CD1 . LEU A 1 327 ? 176.710 169.287 145.064 1.00 83.00  ? 320 LEU A CD1 1 
ATOM   2229  C  CD2 . LEU A 1 327 ? 177.779 170.597 146.913 1.00 83.00  ? 320 LEU A CD2 1 
ATOM   2230  N  N   . LYS A 1 328 ? 181.193 169.551 143.466 1.00 81.19  ? 321 LYS A N   1 
ATOM   2231  C  CA  . LYS A 1 328 ? 181.685 170.509 142.480 1.00 81.19  ? 321 LYS A CA  1 
ATOM   2232  C  C   . LYS A 1 328 ? 181.662 169.917 141.076 1.00 81.19  ? 321 LYS A C   1 
ATOM   2233  O  O   . LYS A 1 328 ? 181.289 170.596 140.110 1.00 81.19  ? 321 LYS A O   1 
ATOM   2234  C  CB  . LYS A 1 328 ? 183.097 170.963 142.850 1.00 81.19  ? 321 LYS A CB  1 
ATOM   2235  C  CG  . LYS A 1 328 ? 183.782 171.802 141.782 1.00 81.19  ? 321 LYS A CG  1 
ATOM   2236  C  CD  . LYS A 1 328 ? 184.945 172.595 142.358 1.00 81.19  ? 321 LYS A CD  1 
ATOM   2237  C  CE  . LYS A 1 328 ? 184.509 173.469 143.525 1.00 81.19  ? 321 LYS A CE  1 
ATOM   2238  N  NZ  . LYS A 1 328 ? 183.231 174.184 143.253 1.00 81.19  ? 321 LYS A NZ  1 
ATOM   2239  N  N   . SER A 1 329 ? 182.061 168.650 140.944 1.00 78.20  ? 322 SER A N   1 
ATOM   2240  C  CA  . SER A 1 329 ? 182.017 167.994 139.641 1.00 78.20  ? 322 SER A CA  1 
ATOM   2241  C  C   . SER A 1 329 ? 180.584 167.864 139.138 1.00 78.20  ? 322 SER A C   1 
ATOM   2242  O  O   . SER A 1 329 ? 180.308 168.105 137.956 1.00 78.20  ? 322 SER A O   1 
ATOM   2243  C  CB  . SER A 1 329 ? 182.688 166.625 139.723 1.00 78.20  ? 322 SER A CB  1 
ATOM   2244  O  OG  . SER A 1 329 ? 184.031 166.741 140.156 1.00 78.20  ? 322 SER A OG  1 
ATOM   2245  N  N   . VAL A 1 330 ? 179.656 167.491 140.022 1.00 75.36  ? 323 VAL A N   1 
ATOM   2246  C  CA  . VAL A 1 330 ? 178.257 167.403 139.611 1.00 75.36  ? 323 VAL A CA  1 
ATOM   2247  C  C   . VAL A 1 330 ? 177.739 168.773 139.191 1.00 75.36  ? 323 VAL A C   1 
ATOM   2248  O  O   . VAL A 1 330 ? 177.001 168.897 138.206 1.00 75.36  ? 323 VAL A O   1 
ATOM   2249  C  CB  . VAL A 1 330 ? 177.399 166.786 140.731 1.00 75.36  ? 323 VAL A CB  1 
ATOM   2250  C  CG1 . VAL A 1 330 ? 175.931 166.815 140.348 1.00 75.36  ? 323 VAL A CG1 1 
ATOM   2251  C  CG2 . VAL A 1 330 ? 177.838 165.361 141.005 1.00 75.36  ? 323 VAL A CG2 1 
ATOM   2252  N  N   . THR A 1 331 ? 178.120 169.825 139.923 1.00 77.30  ? 324 THR A N   1 
ATOM   2253  C  CA  . THR A 1 331 ? 177.659 171.170 139.592 1.00 77.30  ? 324 THR A CA  1 
ATOM   2254  C  C   . THR A 1 331 ? 178.183 171.623 138.237 1.00 77.30  ? 324 THR A C   1 
ATOM   2255  O  O   . THR A 1 331 ? 177.433 172.196 137.440 1.00 77.30  ? 324 THR A O   1 
ATOM   2256  C  CB  . THR A 1 331 ? 178.080 172.171 140.669 1.00 77.30  ? 324 THR A CB  1 
ATOM   2257  O  OG1 . THR A 1 331 ? 179.489 172.070 140.898 1.00 77.30  ? 324 THR A OG1 1 
ATOM   2258  C  CG2 . THR A 1 331 ? 177.329 171.929 141.970 1.00 77.30  ? 324 THR A CG2 1 
ATOM   2259  N  N   . THR A 1 332 ? 179.469 171.393 137.958 1.00 78.09  ? 325 THR A N   1 
ATOM   2260  C  CA  . THR A 1 332 ? 179.993 171.823 136.665 1.00 78.09  ? 325 THR A CA  1 
ATOM   2261  C  C   . THR A 1 332 ? 179.414 170.989 135.527 1.00 78.09  ? 325 THR A C   1 
ATOM   2262  O  O   . THR A 1 332 ? 179.159 171.524 134.441 1.00 78.09  ? 325 THR A O   1 
ATOM   2263  C  CB  . THR A 1 332 ? 181.525 171.788 136.651 1.00 78.09  ? 325 THR A CB  1 
ATOM   2264  O  OG1 . THR A 1 332 ? 182.000 172.251 135.380 1.00 78.09  ? 325 THR A OG1 1 
ATOM   2265  C  CG2 . THR A 1 332 ? 182.056 170.393 136.897 1.00 78.09  ? 325 THR A CG2 1 
ATOM   2266  N  N   . LEU A 1 333 ? 179.164 169.696 135.760 1.00 71.03  ? 326 LEU A N   1 
ATOM   2267  C  CA  . LEU A 1 333 ? 178.497 168.889 134.743 1.00 71.03  ? 326 LEU A CA  1 
ATOM   2268  C  C   . LEU A 1 333 ? 177.089 169.403 134.472 1.00 71.03  ? 326 LEU A C   1 
ATOM   2269  O  O   . LEU A 1 333 ? 176.665 169.498 133.314 1.00 71.03  ? 326 LEU A O   1 
ATOM   2270  C  CB  . LEU A 1 333 ? 178.461 167.425 135.177 1.00 71.03  ? 326 LEU A CB  1 
ATOM   2271  C  CG  . LEU A 1 333 ? 177.856 166.451 134.168 1.00 71.03  ? 326 LEU A CG  1 
ATOM   2272  C  CD1 . LEU A 1 333 ? 178.756 166.325 132.952 1.00 71.03  ? 326 LEU A CD1 1 
ATOM   2273  C  CD2 . LEU A 1 333 ? 177.624 165.096 134.809 1.00 71.03  ? 326 LEU A CD2 1 
ATOM   2274  N  N   . ALA A 1 334 ? 176.351 169.750 135.528 1.00 71.28  ? 327 ALA A N   1 
ATOM   2275  C  CA  . ALA A 1 334 ? 175.006 170.285 135.351 1.00 71.28  ? 327 ALA A CA  1 
ATOM   2276  C  C   . ALA A 1 334 ? 175.033 171.625 134.627 1.00 71.28  ? 327 ALA A C   1 
ATOM   2277  O  O   . ALA A 1 334 ? 174.181 171.891 133.771 1.00 71.28  ? 327 ALA A O   1 
ATOM   2278  C  CB  . ALA A 1 334 ? 174.313 170.420 136.706 1.00 71.28  ? 327 ALA A CB  1 
ATOM   2279  N  N   . MET A 1 335 ? 175.996 172.485 134.963 1.00 75.18  ? 328 MET A N   1 
ATOM   2280  C  CA  . MET A 1 335 ? 176.113 173.769 134.280 1.00 75.18  ? 328 MET A CA  1 
ATOM   2281  C  C   . MET A 1 335 ? 176.412 173.575 132.800 1.00 75.18  ? 328 MET A C   1 
ATOM   2282  O  O   . MET A 1 335 ? 175.850 174.272 131.948 1.00 75.18  ? 328 MET A O   1 
ATOM   2283  C  CB  . MET A 1 335 ? 177.197 174.619 134.941 1.00 75.18  ? 328 MET A CB  1 
ATOM   2284  C  CG  . MET A 1 335 ? 177.242 176.057 134.454 1.00 75.18  ? 328 MET A CG  1 
ATOM   2285  S  SD  . MET A 1 335 ? 178.925 176.697 134.341 1.00 75.18  ? 328 MET A SD  1 
ATOM   2286  C  CE  . MET A 1 335 ? 179.262 176.462 132.598 1.00 75.18  ? 328 MET A CE  1 
ATOM   2287  N  N   . LYS A 1 336 ? 177.296 172.629 132.476 1.00 72.76  ? 329 LYS A N   1 
ATOM   2288  C  CA  . LYS A 1 336 ? 177.567 172.322 131.077 1.00 72.76  ? 329 LYS A CA  1 
ATOM   2289  C  C   . LYS A 1 336 ? 176.331 171.768 130.377 1.00 72.76  ? 329 LYS A C   1 
ATOM   2290  O  O   . LYS A 1 336 ? 176.096 172.075 129.203 1.00 72.76  ? 329 LYS A O   1 
ATOM   2291  C  CB  . LYS A 1 336 ? 178.735 171.339 130.981 1.00 72.76  ? 329 LYS A CB  1 
ATOM   2292  C  CG  . LYS A 1 336 ? 178.783 170.523 129.699 1.00 72.76  ? 329 LYS A CG  1 
ATOM   2293  C  CD  . LYS A 1 336 ? 179.928 169.518 129.723 1.00 72.76  ? 329 LYS A CD  1 
ATOM   2294  C  CE  . LYS A 1 336 ? 181.190 170.114 130.327 1.00 72.76  ? 329 LYS A CE  1 
ATOM   2295  N  NZ  . LYS A 1 336 ? 182.399 169.318 129.982 1.00 72.76  ? 329 LYS A NZ  1 
ATOM   2296  N  N   . ALA A 1 337 ? 175.528 170.972 131.079 1.00 71.49  ? 330 ALA A N   1 
ATOM   2297  C  CA  . ALA A 1 337 ? 174.344 170.352 130.499 1.00 71.49  ? 330 ALA A CA  1 
ATOM   2298  C  C   . ALA A 1 337 ? 173.116 171.255 130.516 1.00 71.49  ? 330 ALA A C   1 
ATOM   2299  O  O   . ALA A 1 337 ? 172.071 170.855 129.992 1.00 71.49  ? 330 ALA A O   1 
ATOM   2300  C  CB  . ALA A 1 337 ? 174.025 169.045 131.231 1.00 71.49  ? 330 ALA A CB  1 
ATOM   2301  N  N   . LYS A 1 338 ? 173.214 172.447 131.106 1.00 71.50  ? 331 LYS A N   1 
ATOM   2302  C  CA  . LYS A 1 338 ? 172.135 173.438 131.113 1.00 71.50  ? 331 LYS A CA  1 
ATOM   2303  C  C   . LYS A 1 338 ? 170.877 172.880 131.790 1.00 71.50  ? 331 LYS A C   1 
ATOM   2304  O  O   . LYS A 1 338 ? 169.835 172.657 131.169 1.00 71.50  ? 331 LYS A O   1 
ATOM   2305  C  CB  . LYS A 1 338 ? 171.835 173.920 129.687 1.00 71.50  ? 331 LYS A CB  1 
ATOM   2306  C  CG  . LYS A 1 338 ? 170.896 175.113 129.606 1.00 71.50  ? 331 LYS A CG  1 
ATOM   2307  C  CD  . LYS A 1 338 ? 171.459 176.310 130.351 1.00 71.50  ? 331 LYS A CD  1 
ATOM   2308  C  CE  . LYS A 1 338 ? 172.722 176.825 129.681 1.00 71.50  ? 331 LYS A CE  1 
ATOM   2309  N  NZ  . LYS A 1 338 ? 172.425 177.506 128.391 1.00 71.50  ? 331 LYS A NZ  1 
ATOM   2310  N  N   . CYS A 1 339 ? 171.012 172.640 133.094 1.00 63.58  ? 332 CYS A N   1 
ATOM   2311  C  CA  . CYS A 1 339 ? 169.909 172.158 133.914 1.00 63.58  ? 332 CYS A CA  1 
ATOM   2312  C  C   . CYS A 1 339 ? 169.987 172.809 135.290 1.00 63.58  ? 332 CYS A C   1 
ATOM   2313  O  O   . CYS A 1 339 ? 170.885 173.607 135.575 1.00 63.58  ? 332 CYS A O   1 
ATOM   2314  C  CB  . CYS A 1 339 ? 169.925 170.629 134.020 1.00 63.58  ? 332 CYS A CB  1 
ATOM   2315  S  SG  . CYS A 1 339 ? 171.507 169.937 134.536 1.00 63.58  ? 332 CYS A SG  1 
ATOM   2316  N  N   . LYS A 1 340 ? 169.032 172.462 136.148 1.00 59.53  ? 333 LYS A N   1 
ATOM   2317  C  CA  . LYS A 1 340 ? 168.950 172.981 137.503 1.00 59.53  ? 333 LYS A CA  1 
ATOM   2318  C  C   . LYS A 1 340 ? 169.779 172.106 138.439 1.00 59.53  ? 333 LYS A C   1 
ATOM   2319  O  O   . LYS A 1 340 ? 170.533 171.232 138.001 1.00 59.53  ? 333 LYS A O   1 
ATOM   2320  C  CB  . LYS A 1 340 ? 167.490 173.051 137.953 1.00 59.53  ? 333 LYS A CB  1 
ATOM   2321  C  CG  . LYS A 1 340 ? 166.663 174.099 137.237 1.00 59.53  ? 333 LYS A CG  1 
ATOM   2322  C  CD  . LYS A 1 340 ? 165.250 174.147 137.791 1.00 59.53  ? 333 LYS A CD  1 
ATOM   2323  C  CE  . LYS A 1 340 ? 164.422 175.213 137.098 1.00 59.53  ? 333 LYS A CE  1 
ATOM   2324  N  NZ  . LYS A 1 340 ? 163.047 175.302 137.662 1.00 59.53  ? 333 LYS A NZ  1 
ATOM   2325  N  N   . LEU A 1 341 ? 169.637 172.335 139.743 1.00 55.49  ? 334 LEU A N   1 
ATOM   2326  C  CA  . LEU A 1 341 ? 170.337 171.551 140.751 1.00 55.49  ? 334 LEU A CA  1 
ATOM   2327  C  C   . LEU A 1 341 ? 169.643 171.708 142.093 1.00 55.49  ? 334 LEU A C   1 
ATOM   2328  O  O   . LEU A 1 341 ? 169.247 172.813 142.471 1.00 55.49  ? 334 LEU A O   1 
ATOM   2329  C  CB  . LEU A 1 341 ? 171.802 171.973 140.873 1.00 55.49  ? 334 LEU A CB  1 
ATOM   2330  C  CG  . LEU A 1 341 ? 172.799 171.086 140.137 1.00 55.49  ? 334 LEU A CG  1 
ATOM   2331  C  CD1 . LEU A 1 341 ? 174.197 171.573 140.392 1.00 55.49  ? 334 LEU A CD1 1 
ATOM   2332  C  CD2 . LEU A 1 341 ? 172.643 169.647 140.588 1.00 55.49  ? 334 LEU A CD2 1 
ATOM   2333  N  N   . THR A 1 342 ? 169.502 170.595 142.808 1.00 58.30  ? 335 THR A N   1 
ATOM   2334  C  CA  . THR A 1 342 ? 168.935 170.592 144.149 1.00 58.30  ? 335 THR A CA  1 
ATOM   2335  C  C   . THR A 1 342 ? 169.826 169.749 145.046 1.00 58.30  ? 335 THR A C   1 
ATOM   2336  O  O   . THR A 1 342 ? 170.170 168.617 144.692 1.00 58.30  ? 335 THR A O   1 
ATOM   2337  C  CB  . THR A 1 342 ? 167.504 170.044 144.148 1.00 58.30  ? 335 THR A CB  1 
ATOM   2338  O  OG1 . THR A 1 342 ? 166.643 170.959 143.459 1.00 58.30  ? 335 THR A OG1 1 
ATOM   2339  C  CG2 . THR A 1 342 ? 167.002 169.864 145.568 1.00 58.30  ? 335 THR A CG2 1 
ATOM   2340  N  N   . ILE A 1 343 ? 170.198 170.296 146.200 1.00 70.18  ? 336 ILE A N   1 
ATOM   2341  C  CA  . ILE A 1 343 ? 171.136 169.654 147.110 1.00 70.18  ? 336 ILE A CA  1 
ATOM   2342  C  C   . ILE A 1 343 ? 170.509 169.565 148.494 1.00 70.18  ? 336 ILE A C   1 
ATOM   2343  O  O   . ILE A 1 343 ? 169.922 170.536 148.984 1.00 70.18  ? 336 ILE A O   1 
ATOM   2344  C  CB  . ILE A 1 343 ? 172.476 170.413 147.169 1.00 70.18  ? 336 ILE A CB  1 
ATOM   2345  C  CG1 . ILE A 1 343 ? 172.228 171.921 147.222 1.00 70.18  ? 336 ILE A CG1 1 
ATOM   2346  C  CG2 . ILE A 1 343 ? 173.344 170.049 145.977 1.00 70.18  ? 336 ILE A CG2 1 
ATOM   2347  C  CD1 . ILE A 1 343 ? 173.491 172.749 147.212 1.00 70.18  ? 336 ILE A CD1 1 
ATOM   2348  N  N   . CYS A 1 344 ? 170.633 168.395 149.121 1.00 81.75  ? 337 CYS A N   1 
ATOM   2349  C  CA  . CYS A 1 344 ? 170.130 168.186 150.469 1.00 81.75  ? 337 CYS A CA  1 
ATOM   2350  C  C   . CYS A 1 344 ? 171.251 168.383 151.475 1.00 81.75  ? 337 CYS A C   1 
ATOM   2351  O  O   . CYS A 1 344 ? 172.256 167.660 151.415 1.00 81.75  ? 337 CYS A O   1 
ATOM   2352  C  CB  . CYS A 1 344 ? 169.532 166.789 150.613 1.00 81.75  ? 337 CYS A CB  1 
ATOM   2353  S  SG  . CYS A 1 344 ? 168.098 166.718 151.705 1.00 81.75  ? 337 CYS A SG  1 
ATOM   2354  N  N   . PRO A 1 345 ? 171.133 169.327 152.404 1.00 87.37  ? 338 PRO A N   1 
ATOM   2355  C  CA  . PRO A 1 345 ? 172.162 169.482 153.437 1.00 87.37  ? 338 PRO A CA  1 
ATOM   2356  C  C   . PRO A 1 345 ? 172.101 168.345 154.447 1.00 87.37  ? 338 PRO A C   1 
ATOM   2357  O  O   . PRO A 1 345 ? 171.119 167.607 154.546 1.00 87.37  ? 338 PRO A O   1 
ATOM   2358  C  CB  . PRO A 1 345 ? 171.818 170.829 154.074 1.00 87.37  ? 338 PRO A CB  1 
ATOM   2359  C  CG  . PRO A 1 345 ? 170.346 170.956 153.881 1.00 87.37  ? 338 PRO A CG  1 
ATOM   2360  C  CD  . PRO A 1 345 ? 170.038 170.299 152.561 1.00 87.37  ? 338 PRO A CD  1 
ATOM   2361  N  N   . GLU A 1 346 ? 173.187 168.214 155.212 1.00 91.28  ? 339 GLU A N   1 
ATOM   2362  C  CA  . GLU A 1 346 ? 173.347 167.066 156.098 1.00 91.28  ? 339 GLU A CA  1 
ATOM   2363  C  C   . GLU A 1 346 ? 172.345 167.051 157.246 1.00 91.28  ? 339 GLU A C   1 
ATOM   2364  O  O   . GLU A 1 346 ? 172.137 165.993 157.849 1.00 91.28  ? 339 GLU A O   1 
ATOM   2365  C  CB  . GLU A 1 346 ? 174.774 167.025 156.651 1.00 91.28  ? 339 GLU A CB  1 
ATOM   2366  C  CG  . GLU A 1 346 ? 174.951 167.709 157.996 1.00 91.28  ? 339 GLU A CG  1 
ATOM   2367  C  CD  . GLU A 1 346 ? 175.069 169.216 157.878 1.00 91.28  ? 339 GLU A CD  1 
ATOM   2368  O  OE1 . GLU A 1 346 ? 174.946 169.742 156.751 1.00 91.28  ? 339 GLU A OE1 1 
ATOM   2369  O  OE2 . GLU A 1 346 ? 175.284 169.878 158.915 1.00 91.28  ? 339 GLU A OE2 1 
ATOM   2370  N  N   . GLU A 1 347 ? 171.727 168.190 157.571 1.00 91.70  ? 340 GLU A N   1 
ATOM   2371  C  CA  . GLU A 1 347 ? 170.752 168.208 158.659 1.00 91.70  ? 340 GLU A CA  1 
ATOM   2372  C  C   . GLU A 1 347 ? 169.538 167.348 158.332 1.00 91.70  ? 340 GLU A C   1 
ATOM   2373  O  O   . GLU A 1 347 ? 169.068 166.578 159.178 1.00 91.70  ? 340 GLU A O   1 
ATOM   2374  C  CB  . GLU A 1 347 ? 170.327 169.645 158.972 1.00 91.70  ? 340 GLU A CB  1 
ATOM   2375  C  CG  . GLU A 1 347 ? 171.456 170.574 159.420 1.00 91.70  ? 340 GLU A CG  1 
ATOM   2376  C  CD  . GLU A 1 347 ? 172.321 171.075 158.278 1.00 91.70  ? 340 GLU A CD  1 
ATOM   2377  O  OE1 . GLU A 1 347 ? 172.188 170.556 157.151 1.00 91.70  ? 340 GLU A OE1 1 
ATOM   2378  O  OE2 . GLU A 1 347 ? 173.136 171.993 158.508 1.00 91.70  ? 340 GLU A OE2 1 
ATOM   2379  N  N   . GLU A 1 348 ? 169.015 167.462 157.113 1.00 86.66  ? 341 GLU A N   1 
ATOM   2380  C  CA  . GLU A 1 348 ? 167.905 166.629 156.671 1.00 86.66  ? 341 GLU A CA  1 
ATOM   2381  C  C   . GLU A 1 348 ? 168.371 165.341 156.004 1.00 86.66  ? 341 GLU A C   1 
ATOM   2382  O  O   . GLU A 1 348 ? 167.548 164.458 155.740 1.00 86.66  ? 341 GLU A O   1 
ATOM   2383  C  CB  . GLU A 1 348 ? 167.010 167.423 155.710 1.00 86.66  ? 341 GLU A CB  1 
ATOM   2384  C  CG  . GLU A 1 348 ? 165.638 166.814 155.462 1.00 86.66  ? 341 GLU A CG  1 
ATOM   2385  C  CD  . GLU A 1 348 ? 164.564 167.431 156.334 1.00 86.66  ? 341 GLU A CD  1 
ATOM   2386  O  OE1 . GLU A 1 348 ? 164.891 168.337 157.128 1.00 86.66  ? 341 GLU A OE1 1 
ATOM   2387  O  OE2 . GLU A 1 348 ? 163.394 167.010 156.226 1.00 86.66  ? 341 GLU A OE2 1 
ATOM   2388  N  N   . ASN A 1 349 ? 169.676 165.224 155.750 1.00 83.34  ? 342 ASN A N   1 
ATOM   2389  C  CA  . ASN A 1 349 ? 170.216 164.042 155.025 1.00 83.34  ? 342 ASN A CA  1 
ATOM   2390  C  C   . ASN A 1 349 ? 170.263 162.816 155.943 1.00 83.34  ? 342 ASN A C   1 
ATOM   2391  O  O   . ASN A 1 349 ? 170.011 161.703 155.440 1.00 83.34  ? 342 ASN A O   1 
ATOM   2392  C  CB  . ASN A 1 349 ? 171.609 164.352 154.478 1.00 83.34  ? 342 ASN A CB  1 
ATOM   2393  C  CG  . ASN A 1 349 ? 172.115 163.291 153.530 1.00 83.34  ? 342 ASN A CG  1 
ATOM   2394  O  OD1 . ASN A 1 349 ? 173.066 162.581 153.844 1.00 83.34  ? 342 ASN A OD1 1 
ATOM   2395  N  ND2 . ASN A 1 349 ? 171.467 163.158 152.384 1.00 83.34  ? 342 ASN A ND2 1 
ATOM   2396  N  N   . MET A 1 350 ? 170.584 163.009 157.224 1.00 83.31  ? 343 MET A N   1 
ATOM   2397  C  CA  . MET A 1 350 ? 170.700 161.919 158.196 1.00 83.31  ? 343 MET A CA  1 
ATOM   2398  C  C   . MET A 1 350 ? 171.680 160.846 157.726 1.00 83.31  ? 343 MET A C   1 
ATOM   2399  O  O   . MET A 1 350 ? 171.432 159.648 157.869 1.00 83.31  ? 343 MET A O   1 
ATOM   2400  C  CB  . MET A 1 350 ? 169.333 161.306 158.511 1.00 83.31  ? 343 MET A CB  1 
ATOM   2401  C  CG  . MET A 1 350 ? 168.272 162.320 158.899 1.00 83.31  ? 343 MET A CG  1 
ATOM   2402  S  SD  . MET A 1 350 ? 168.155 162.540 160.685 1.00 83.31  ? 343 MET A SD  1 
ATOM   2403  C  CE  . MET A 1 350 ? 167.692 160.889 161.201 1.00 83.31  ? 343 MET A CE  1 
ATOM   2404  N  N   . ASP A 1 351 ? 172.804 161.286 157.155 1.00 80.32  ? 344 ASP A N   1 
ATOM   2405  C  CA  . ASP A 1 351 ? 173.896 160.398 156.751 1.00 80.32  ? 344 ASP A CA  1 
ATOM   2406  C  C   . ASP A 1 351 ? 173.435 159.350 155.739 1.00 80.32  ? 344 ASP A C   1 
ATOM   2407  O  O   . ASP A 1 351 ? 173.878 158.201 155.762 1.00 80.32  ? 344 ASP A O   1 
ATOM   2408  C  CB  . ASP A 1 351 ? 174.539 159.727 157.967 1.00 80.32  ? 344 ASP A CB  1 
ATOM   2409  C  CG  . ASP A 1 351 ? 175.071 160.729 158.971 1.00 80.32  ? 344 ASP A CG  1 
ATOM   2410  O  OD1 . ASP A 1 351 ? 174.943 161.945 158.722 1.00 80.32  ? 344 ASP A OD1 1 
ATOM   2411  O  OD2 . ASP A 1 351 ? 175.618 160.300 160.008 1.00 80.32  ? 344 ASP A OD2 1 
ATOM   2412  N  N   . ASP A 1 352 ? 172.537 159.748 154.843 1.00 72.25  ? 345 ASP A N   1 
ATOM   2413  C  CA  . ASP A 1 352 ? 172.079 158.901 153.749 1.00 72.25  ? 345 ASP A CA  1 
ATOM   2414  C  C   . ASP A 1 352 ? 172.367 159.611 152.436 1.00 72.25  ? 345 ASP A C   1 
ATOM   2415  O  O   . ASP A 1 352 ? 171.876 160.721 152.209 1.00 72.25  ? 345 ASP A O   1 
ATOM   2416  C  CB  . ASP A 1 352 ? 170.585 158.594 153.876 1.00 72.25  ? 345 ASP A CB  1 
ATOM   2417  C  CG  . ASP A 1 352 ? 170.095 157.638 152.811 1.00 72.25  ? 345 ASP A CG  1 
ATOM   2418  O  OD1 . ASP A 1 352 ? 170.918 157.196 151.982 1.00 72.25  ? 345 ASP A OD1 1 
ATOM   2419  O  OD2 . ASP A 1 352 ? 168.886 157.327 152.799 1.00 72.25  ? 345 ASP A OD2 1 
ATOM   2420  N  N   . GLN A 1 353 ? 173.158 158.975 151.571 1.00 69.97  ? 346 GLN A N   1 
ATOM   2421  C  CA  . GLN A 1 353 ? 173.608 159.618 150.343 1.00 69.97  ? 346 GLN A CA  1 
ATOM   2422  C  C   . GLN A 1 353 ? 173.103 158.928 149.083 1.00 69.97  ? 346 GLN A C   1 
ATOM   2423  O  O   . GLN A 1 353 ? 173.486 159.332 147.979 1.00 69.97  ? 346 GLN A O   1 
ATOM   2424  C  CB  . GLN A 1 353 ? 175.141 159.697 150.296 1.00 69.97  ? 346 GLN A CB  1 
ATOM   2425  C  CG  . GLN A 1 353 ? 175.892 158.373 150.107 1.00 69.97  ? 346 GLN A CG  1 
ATOM   2426  C  CD  . GLN A 1 353 ? 175.942 157.485 151.345 1.00 69.97  ? 346 GLN A CD  1 
ATOM   2427  O  OE1 . GLN A 1 353 ? 175.414 157.823 152.403 1.00 69.97  ? 346 GLN A OE1 1 
ATOM   2428  N  NE2 . GLN A 1 353 ? 176.588 156.334 151.209 1.00 69.97  ? 346 GLN A NE2 1 
ATOM   2429  N  N   . TRP A 1 354 ? 172.256 157.912 149.210 1.00 64.86  ? 347 TRP A N   1 
ATOM   2430  C  CA  . TRP A 1 354 ? 171.775 157.149 148.060 1.00 64.86  ? 347 TRP A CA  1 
ATOM   2431  C  C   . TRP A 1 354 ? 170.390 157.668 147.692 1.00 64.86  ? 347 TRP A C   1 
ATOM   2432  O  O   . TRP A 1 354 ? 169.369 157.085 148.055 1.00 64.86  ? 347 TRP A O   1 
ATOM   2433  C  CB  . TRP A 1 354 ? 171.770 155.659 148.374 1.00 64.86  ? 347 TRP A CB  1 
ATOM   2434  C  CG  . TRP A 1 354 ? 173.149 155.102 148.489 1.00 64.86  ? 347 TRP A CG  1 
ATOM   2435  C  CD1 . TRP A 1 354 ? 174.157 155.222 147.581 1.00 64.86  ? 347 TRP A CD1 1 
ATOM   2436  C  CD2 . TRP A 1 354 ? 173.687 154.370 149.592 1.00 64.86  ? 347 TRP A CD2 1 
ATOM   2437  N  NE1 . TRP A 1 354 ? 175.286 154.594 148.041 1.00 64.86  ? 347 TRP A NE1 1 
ATOM   2438  C  CE2 . TRP A 1 354 ? 175.023 154.063 149.276 1.00 64.86  ? 347 TRP A CE2 1 
ATOM   2439  C  CE3 . TRP A 1 354 ? 173.167 153.936 150.814 1.00 64.86  ? 347 TRP A CE3 1 
ATOM   2440  C  CZ2 . TRP A 1 354 ? 175.844 153.346 150.135 1.00 64.86  ? 347 TRP A CZ2 1 
ATOM   2441  C  CZ3 . TRP A 1 354 ? 173.984 153.222 151.666 1.00 64.86  ? 347 TRP A CZ3 1 
ATOM   2442  C  CH2 . TRP A 1 354 ? 175.308 152.933 151.323 1.00 64.86  ? 347 TRP A CH2 1 
ATOM   2443  N  N   . MET A 1 355 ? 170.364 158.782 146.959 1.00 59.78  ? 348 MET A N   1 
ATOM   2444  C  CA  . MET A 1 355 ? 169.101 159.345 146.501 1.00 59.78  ? 348 MET A CA  1 
ATOM   2445  C  C   . MET A 1 355 ? 168.430 158.462 145.460 1.00 59.78  ? 348 MET A C   1 
ATOM   2446  O  O   . MET A 1 355 ? 167.197 158.417 145.396 1.00 59.78  ? 348 MET A O   1 
ATOM   2447  C  CB  . MET A 1 355 ? 169.323 160.739 145.917 1.00 59.78  ? 348 MET A CB  1 
ATOM   2448  C  CG  . MET A 1 355 ? 168.209 161.724 146.215 1.00 59.78  ? 348 MET A CG  1 
ATOM   2449  S  SD  . MET A 1 355 ? 168.830 163.384 146.532 1.00 59.78  ? 348 MET A SD  1 
ATOM   2450  C  CE  . MET A 1 355 ? 169.122 163.314 148.294 1.00 59.78  ? 348 MET A CE  1 
ATOM   2451  N  N   . GLN A 1 356 ? 169.219 157.765 144.641 1.00 54.06  ? 349 GLN A N   1 
ATOM   2452  C  CA  . GLN A 1 356 ? 168.658 156.955 143.564 1.00 54.06  ? 349 GLN A CA  1 
ATOM   2453  C  C   . GLN A 1 356 ? 167.797 155.821 144.106 1.00 54.06  ? 349 GLN A C   1 
ATOM   2454  O  O   . GLN A 1 356 ? 166.727 155.533 143.559 1.00 54.06  ? 349 GLN A O   1 
ATOM   2455  C  CB  . GLN A 1 356 ? 169.785 156.403 142.693 1.00 54.06  ? 349 GLN A CB  1 
ATOM   2456  C  CG  . GLN A 1 356 ? 169.357 155.395 141.633 1.00 54.06  ? 349 GLN A CG  1 
ATOM   2457  C  CD  . GLN A 1 356 ? 168.343 155.948 140.651 1.00 54.06  ? 349 GLN A CD  1 
ATOM   2458  O  OE1 . GLN A 1 356 ? 168.705 156.434 139.580 1.00 54.06  ? 349 GLN A OE1 1 
ATOM   2459  N  NE2 . GLN A 1 356 ? 167.064 155.853 140.997 1.00 54.06  ? 349 GLN A NE2 1 
ATOM   2460  N  N   . ASP A 1 357 ? 168.242 155.171 145.180 1.00 52.48  ? 350 ASP A N   1 
ATOM   2461  C  CA  . ASP A 1 357 ? 167.562 153.992 145.698 1.00 52.48  ? 350 ASP A CA  1 
ATOM   2462  C  C   . ASP A 1 357 ? 166.249 154.306 146.402 1.00 52.48  ? 350 ASP A C   1 
ATOM   2463  O  O   . ASP A 1 357 ? 165.476 153.380 146.667 1.00 52.48  ? 350 ASP A O   1 
ATOM   2464  C  CB  . ASP A 1 357 ? 168.481 153.242 146.666 1.00 52.48  ? 350 ASP A CB  1 
ATOM   2465  C  CG  . ASP A 1 357 ? 169.831 152.924 146.060 1.00 52.48  ? 350 ASP A CG  1 
ATOM   2466  O  OD1 . ASP A 1 357 ? 170.045 153.258 144.877 1.00 52.48  ? 350 ASP A OD1 1 
ATOM   2467  O  OD2 . ASP A 1 357 ? 170.679 152.340 146.767 1.00 52.48  ? 350 ASP A OD2 1 
ATOM   2468  N  N   . GLU A 1 358 ? 165.974 155.570 146.714 1.00 50.73  ? 351 GLU A N   1 
ATOM   2469  C  CA  . GLU A 1 358 ? 164.807 155.924 147.512 1.00 50.73  ? 351 GLU A CA  1 
ATOM   2470  C  C   . GLU A 1 358 ? 163.644 156.452 146.685 1.00 50.73  ? 351 GLU A C   1 
ATOM   2471  O  O   . GLU A 1 358 ? 162.488 156.138 146.982 1.00 50.73  ? 351 GLU A O   1 
ATOM   2472  C  CB  . GLU A 1 358 ? 165.189 156.967 148.569 1.00 50.73  ? 351 GLU A CB  1 
ATOM   2473  C  CG  . GLU A 1 358 ? 164.011 157.503 149.362 1.00 50.73  ? 351 GLU A CG  1 
ATOM   2474  C  CD  . GLU A 1 358 ? 163.718 156.677 150.596 1.00 50.73  ? 351 GLU A CD  1 
ATOM   2475  O  OE1 . GLU A 1 358 ? 164.555 155.821 150.951 1.00 50.73  ? 351 GLU A OE1 1 
ATOM   2476  O  OE2 . GLU A 1 358 ? 162.646 156.875 151.206 1.00 50.73  ? 351 GLU A OE2 1 
ATOM   2477  N  N   . MET A 1 359 ? 163.963 157.274 145.682 1.00 44.45  ? 352 MET A N   1 
ATOM   2478  C  CA  . MET A 1 359 ? 162.876 157.932 144.916 1.00 44.45  ? 352 MET A CA  1 
ATOM   2479  C  C   . MET A 1 359 ? 163.095 157.790 143.410 1.00 44.45  ? 352 MET A C   1 
ATOM   2480  O  O   . MET A 1 359 ? 164.265 157.751 142.980 1.00 44.45  ? 352 MET A O   1 
ATOM   2481  C  CB  . MET A 1 359 ? 162.818 159.422 145.266 1.00 44.45  ? 352 MET A CB  1 
ATOM   2482  C  CG  . MET A 1 359 ? 164.172 160.101 145.197 1.00 44.45  ? 352 MET A CG  1 
ATOM   2483  S  SD  . MET A 1 359 ? 164.327 161.512 146.318 1.00 44.45  ? 352 MET A SD  1 
ATOM   2484  C  CE  . MET A 1 359 ? 165.192 160.743 147.686 1.00 44.45  ? 352 MET A CE  1 
ATOM   2485  N  N   . GLU A 1 360 ? 162.005 157.700 142.651 1.00 40.54  ? 353 GLU A N   1 
ATOM   2486  C  CA  . GLU A 1 360 ? 162.061 157.646 141.196 1.00 40.54  ? 353 GLU A CA  1 
ATOM   2487  C  C   . GLU A 1 360 ? 161.042 158.616 140.623 1.00 40.54  ? 353 GLU A C   1 
ATOM   2488  O  O   . GLU A 1 360 ? 159.895 158.648 141.067 1.00 40.54  ? 353 GLU A O   1 
ATOM   2489  C  CB  . GLU A 1 360 ? 161.791 156.232 140.675 1.00 40.54  ? 353 GLU A CB  1 
ATOM   2490  C  CG  . GLU A 1 360 ? 162.005 156.066 139.184 1.00 40.54  ? 353 GLU A CG  1 
ATOM   2491  C  CD  . GLU A 1 360 ? 163.430 155.682 138.827 1.00 40.54  ? 353 GLU A CD  1 
ATOM   2492  O  OE1 . GLU A 1 360 ? 164.027 154.855 139.546 1.00 40.54  ? 353 GLU A OE1 1 
ATOM   2493  O  OE2 . GLU A 1 360 ? 163.951 156.203 137.820 1.00 40.54  ? 353 GLU A OE2 1 
ATOM   2494  N  N   . ILE A 1 361 ? 161.490 159.432 139.661 1.00 32.99  ? 354 ILE A N   1 
ATOM   2495  C  CA  . ILE A 1 361 ? 160.605 160.508 139.126 1.00 32.99  ? 354 ILE A CA  1 
ATOM   2496  C  C   . ILE A 1 361 ? 160.012 160.121 137.772 1.00 32.99  ? 354 ILE A C   1 
ATOM   2497  O  O   . ILE A 1 361 ? 160.793 159.817 136.849 1.00 32.99  ? 354 ILE A O   1 
ATOM   2498  C  CB  . ILE A 1 361 ? 161.369 161.844 139.029 1.00 32.99  ? 354 ILE A CB  1 
ATOM   2499  C  CG1 . ILE A 1 361 ? 162.120 162.171 140.322 1.00 32.99  ? 354 ILE A CG1 1 
ATOM   2500  C  CG2 . ILE A 1 361 ? 160.425 162.967 138.631 1.00 32.99  ? 354 ILE A CG2 1 
ATOM   2501  C  CD1 . ILE A 1 361 ? 161.226 162.651 141.439 1.00 32.99  ? 354 ILE A CD1 1 
ATOM   2502  N  N   . GLY A 1 362 ? 158.685 160.134 137.667 1.00 26.70  ? 355 GLY A N   1 
ATOM   2503  C  CA  . GLY A 1 362 ? 157.991 159.889 136.419 1.00 26.70  ? 355 GLY A CA  1 
ATOM   2504  C  C   . GLY A 1 362 ? 157.023 161.018 136.149 1.00 26.70  ? 355 GLY A C   1 
ATOM   2505  O  O   . GLY A 1 362 ? 157.084 162.042 136.829 1.00 26.70  ? 355 GLY A O   1 
ATOM   2506  N  N   . TYR A 1 363 ? 156.116 160.860 135.190 1.00 21.08  ? 356 TYR A N   1 
ATOM   2507  C  CA  . TYR A 1 363 ? 155.152 161.910 134.901 1.00 21.08  ? 356 TYR A CA  1 
ATOM   2508  C  C   . TYR A 1 363 ? 153.785 161.295 134.654 1.00 21.08  ? 356 TYR A C   1 
ATOM   2509  O  O   . TYR A 1 363 ? 153.667 160.127 134.281 1.00 21.08  ? 356 TYR A O   1 
ATOM   2510  C  CB  . TYR A 1 363 ? 155.579 162.757 133.693 1.00 21.08  ? 356 TYR A CB  1 
ATOM   2511  C  CG  . TYR A 1 363 ? 155.516 162.043 132.361 1.00 21.08  ? 356 TYR A CG  1 
ATOM   2512  C  CD1 . TYR A 1 363 ? 156.567 161.254 131.924 1.00 21.08  ? 356 TYR A CD1 1 
ATOM   2513  C  CD2 . TYR A 1 363 ? 154.414 162.177 131.533 1.00 21.08  ? 356 TYR A CD2 1 
ATOM   2514  C  CE1 . TYR A 1 363 ? 156.514 160.607 130.708 1.00 21.08  ? 356 TYR A CE1 1 
ATOM   2515  C  CE2 . TYR A 1 363 ? 154.353 161.535 130.317 1.00 21.08  ? 356 TYR A CE2 1 
ATOM   2516  C  CZ  . TYR A 1 363 ? 155.404 160.752 129.909 1.00 21.08  ? 356 TYR A CZ  1 
ATOM   2517  O  OH  . TYR A 1 363 ? 155.344 160.111 128.695 1.00 21.08  ? 356 TYR A OH  1 
ATOM   2518  N  N   . ILE A 1 364 ? 152.745 162.096 134.877 1.00 23.40  ? 357 ILE A N   1 
ATOM   2519  C  CA  . ILE A 1 364 ? 151.385 161.746 134.492 1.00 23.40  ? 357 ILE A CA  1 
ATOM   2520  C  C   . ILE A 1 364 ? 150.829 162.898 133.669 1.00 23.40  ? 357 ILE A C   1 
ATOM   2521  O  O   . ILE A 1 364 ? 150.970 164.065 134.053 1.00 23.40  ? 357 ILE A O   1 
ATOM   2522  C  CB  . ILE A 1 364 ? 150.491 161.453 135.711 1.00 23.40  ? 357 ILE A CB  1 
ATOM   2523  C  CG1 . ILE A 1 364 ? 150.547 162.599 136.718 1.00 23.40  ? 357 ILE A CG1 1 
ATOM   2524  C  CG2 . ILE A 1 364 ? 150.911 160.161 136.370 1.00 23.40  ? 357 ILE A CG2 1 
ATOM   2525  C  CD1 . ILE A 1 364 ? 149.661 162.386 137.917 1.00 23.40  ? 357 ILE A CD1 1 
ATOM   2526  N  N   . GLN A 1 365 ? 150.217 162.577 132.534 1.00 25.13  ? 358 GLN A N   1 
ATOM   2527  C  CA  . GLN A 1 365 ? 149.794 163.600 131.594 1.00 25.13  ? 358 GLN A CA  1 
ATOM   2528  C  C   . GLN A 1 365 ? 148.379 163.338 131.103 1.00 25.13  ? 358 GLN A C   1 
ATOM   2529  O  O   . GLN A 1 365 ? 147.900 162.203 131.073 1.00 25.13  ? 358 GLN A O   1 
ATOM   2530  C  CB  . GLN A 1 365 ? 150.763 163.698 130.408 1.00 25.13  ? 358 GLN A CB  1 
ATOM   2531  C  CG  . GLN A 1 365 ? 150.425 162.835 129.214 1.00 25.13  ? 358 GLN A CG  1 
ATOM   2532  C  CD  . GLN A 1 365 ? 151.287 163.166 128.014 1.00 25.13  ? 358 GLN A CD  1 
ATOM   2533  O  OE1 . GLN A 1 365 ? 151.376 164.321 127.601 1.00 25.13  ? 358 GLN A OE1 1 
ATOM   2534  N  NE2 . GLN A 1 365 ? 151.941 162.155 127.457 1.00 25.13  ? 358 GLN A NE2 1 
ATOM   2535  N  N   . ALA A 1 366 ? 147.718 164.427 130.728 1.00 30.07  ? 359 ALA A N   1 
ATOM   2536  C  CA  . ALA A 1 366 ? 146.367 164.434 130.193 1.00 30.07  ? 359 ALA A CA  1 
ATOM   2537  C  C   . ALA A 1 366 ? 146.283 165.578 129.196 1.00 30.07  ? 359 ALA A C   1 
ATOM   2538  O  O   . ALA A 1 366 ? 147.104 166.502 129.245 1.00 30.07  ? 359 ALA A O   1 
ATOM   2539  C  CB  . ALA A 1 366 ? 145.330 164.598 131.312 1.00 30.07  ? 359 ALA A CB  1 
ATOM   2540  N  N   . PRO A 1 367 ? 145.295 165.556 128.277 1.00 32.22  ? 360 PRO A N   1 
ATOM   2541  C  CA  . PRO A 1 367 ? 145.288 166.532 127.174 1.00 32.22  ? 360 PRO A CA  1 
ATOM   2542  C  C   . PRO A 1 367 ? 145.449 167.988 127.587 1.00 32.22  ? 360 PRO A C   1 
ATOM   2543  O  O   . PRO A 1 367 ? 145.845 168.818 126.763 1.00 32.22  ? 360 PRO A O   1 
ATOM   2544  C  CB  . PRO A 1 367 ? 143.920 166.302 126.523 1.00 32.22  ? 360 PRO A CB  1 
ATOM   2545  C  CG  . PRO A 1 367 ? 143.604 164.896 126.817 1.00 32.22  ? 360 PRO A CG  1 
ATOM   2546  C  CD  . PRO A 1 367 ? 144.160 164.621 128.178 1.00 32.22  ? 360 PRO A CD  1 
ATOM   2547  N  N   . HIS A 1 368 ? 145.154 168.320 128.844 1.00 35.97  ? 361 HIS A N   1 
ATOM   2548  C  CA  . HIS A 1 368 ? 145.221 169.701 129.296 1.00 35.97  ? 361 HIS A CA  1 
ATOM   2549  C  C   . HIS A 1 368 ? 146.363 169.993 130.262 1.00 35.97  ? 361 HIS A C   1 
ATOM   2550  O  O   . HIS A 1 368 ? 146.639 171.171 130.513 1.00 35.97  ? 361 HIS A O   1 
ATOM   2551  C  CB  . HIS A 1 368 ? 143.893 170.114 129.951 1.00 35.97  ? 361 HIS A CB  1 
ATOM   2552  C  CG  . HIS A 1 368 ? 143.532 169.306 131.156 1.00 35.97  ? 361 HIS A CG  1 
ATOM   2553  N  ND1 . HIS A 1 368 ? 144.109 169.510 132.390 1.00 35.97  ? 361 HIS A ND1 1 
ATOM   2554  C  CD2 . HIS A 1 368 ? 142.659 168.284 131.314 1.00 35.97  ? 361 HIS A CD2 1 
ATOM   2555  C  CE1 . HIS A 1 368 ? 143.603 168.652 133.258 1.00 35.97  ? 361 HIS A CE1 1 
ATOM   2556  N  NE2 . HIS A 1 368 ? 142.721 167.897 132.630 1.00 35.97  ? 361 HIS A NE2 1 
ATOM   2557  N  N   . LYS A 1 369 ? 147.040 168.978 130.801 1.00 33.51  ? 362 LYS A N   1 
ATOM   2558  C  CA  . LYS A 1 369 ? 148.114 169.245 131.749 1.00 33.51  ? 362 LYS A CA  1 
ATOM   2559  C  C   . LYS A 1 369 ? 148.985 168.013 131.933 1.00 33.51  ? 362 LYS A C   1 
ATOM   2560  O  O   . LYS A 1 369 ? 148.478 166.894 132.014 1.00 33.51  ? 362 LYS A O   1 
ATOM   2561  C  CB  . LYS A 1 369 ? 147.563 169.692 133.106 1.00 33.51  ? 362 LYS A CB  1 
ATOM   2562  C  CG  . LYS A 1 369 ? 148.576 170.444 133.945 1.00 33.51  ? 362 LYS A CG  1 
ATOM   2563  C  CD  . LYS A 1 369 ? 147.941 171.046 135.180 1.00 33.51  ? 362 LYS A CD  1 
ATOM   2564  C  CE  . LYS A 1 369 ? 148.888 172.026 135.844 1.00 33.51  ? 362 LYS A CE  1 
ATOM   2565  N  NZ  . LYS A 1 369 ? 148.312 173.393 135.929 1.00 33.51  ? 362 LYS A NZ  1 
ATOM   2566  N  N   . THR A 1 370 ? 150.301 168.242 132.011 1.00 28.82  ? 363 THR A N   1 
ATOM   2567  C  CA  . THR A 1 370 ? 151.264 167.139 132.270 1.00 28.82  ? 363 THR A CA  1 
ATOM   2568  C  C   . THR A 1 370 ? 152.113 167.538 133.481 1.00 28.82  ? 363 THR A C   1 
ATOM   2569  O  O   . THR A 1 370 ? 152.751 168.608 133.423 1.00 28.82  ? 363 THR A O   1 
ATOM   2570  C  CB  . THR A 1 370 ? 152.109 166.830 131.027 1.00 28.82  ? 363 THR A CB  1 
ATOM   2571  O  OG1 . THR A 1 370 ? 152.849 165.636 131.287 1.00 28.82  ? 363 THR A OG1 1 
ATOM   2572  C  CG2 . THR A 1 370 ? 153.057 167.950 130.657 1.00 28.82  ? 363 THR A CG2 1 
ATOM   2573  N  N   . LEU A 1 371 ? 152.108 166.727 134.540 1.00 27.61  ? 364 LEU A N   1 
ATOM   2574  C  CA  . LEU A 1 371 ? 152.828 167.057 135.760 1.00 27.61  ? 364 LEU A CA  1 
ATOM   2575  C  C   . LEU A 1 371 ? 153.628 165.860 136.254 1.00 27.61  ? 364 LEU A C   1 
ATOM   2576  O  O   . LEU A 1 371 ? 153.171 164.712 136.135 1.00 27.61  ? 364 LEU A O   1 
ATOM   2577  C  CB  . LEU A 1 371 ? 151.877 167.546 136.864 1.00 27.61  ? 364 LEU A CB  1 
ATOM   2578  C  CG  . LEU A 1 371 ? 150.789 166.618 137.403 1.00 27.61  ? 364 LEU A CG  1 
ATOM   2579  C  CD1 . LEU A 1 371 ? 150.442 166.977 138.831 1.00 27.61  ? 364 LEU A CD1 1 
ATOM   2580  C  CD2 . LEU A 1 371 ? 149.555 166.723 136.542 1.00 27.61  ? 364 LEU A CD2 1 
ATOM   2581  N  N   . PRO A 1 372 ? 154.823 166.090 136.785 1.00 25.63  ? 365 PRO A N   1 
ATOM   2582  C  CA  . PRO A 1 372 ? 155.631 164.980 137.294 1.00 25.63  ? 365 PRO A CA  1 
ATOM   2583  C  C   . PRO A 1 372 ? 155.089 164.435 138.606 1.00 25.63  ? 365 PRO A C   1 
ATOM   2584  O  O   . PRO A 1 372 ? 154.286 165.063 139.299 1.00 25.63  ? 365 PRO A O   1 
ATOM   2585  C  CB  . PRO A 1 372 ? 157.017 165.605 137.482 1.00 25.63  ? 365 PRO A CB  1 
ATOM   2586  C  CG  . PRO A 1 372 ? 156.758 167.057 137.620 1.00 25.63  ? 365 PRO A CG  1 
ATOM   2587  C  CD  . PRO A 1 372 ? 155.577 167.353 136.755 1.00 25.63  ? 365 PRO A CD  1 
ATOM   2588  N  N   . VAL A 1 373 ? 155.549 163.231 138.934 1.00 29.03  ? 366 VAL A N   1 
ATOM   2589  C  CA  . VAL A 1 373 ? 155.147 162.518 140.141 1.00 29.03  ? 366 VAL A CA  1 
ATOM   2590  C  C   . VAL A 1 373 ? 156.351 161.751 140.669 1.00 29.03  ? 366 VAL A C   1 
ATOM   2591  O  O   . VAL A 1 373 ? 157.067 161.089 139.910 1.00 29.03  ? 366 VAL A O   1 
ATOM   2592  C  CB  . VAL A 1 373 ? 153.958 161.575 139.865 1.00 29.03  ? 366 VAL A CB  1 
ATOM   2593  C  CG1 . VAL A 1 373 ? 153.885 160.484 140.910 1.00 29.03  ? 366 VAL A CG1 1 
ATOM   2594  C  CG2 . VAL A 1 373 ? 152.666 162.356 139.842 1.00 29.03  ? 366 VAL A CG2 1 
ATOM   2595  N  N   . VAL A 1 374 ? 156.570 161.837 141.979 1.00 34.23  ? 367 VAL A N   1 
ATOM   2596  C  CA  . VAL A 1 374 ? 157.671 161.150 142.642 1.00 34.23  ? 367 VAL A CA  1 
ATOM   2597  C  C   . VAL A 1 374 ? 157.144 159.867 143.271 1.00 34.23  ? 367 VAL A C   1 
ATOM   2598  O  O   . VAL A 1 374 ? 156.095 159.866 143.931 1.00 34.23  ? 367 VAL A O   1 
ATOM   2599  C  CB  . VAL A 1 374 ? 158.348 162.054 143.687 1.00 34.23  ? 367 VAL A CB  1 
ATOM   2600  C  CG1 . VAL A 1 374 ? 157.339 162.588 144.680 1.00 34.23  ? 367 VAL A CG1 1 
ATOM   2601  C  CG2 . VAL A 1 374 ? 159.447 161.301 144.405 1.00 34.23  ? 367 VAL A CG2 1 
ATOM   2602  N  N   . PHE A 1 375 ? 157.867 158.774 143.053 1.00 38.72  ? 368 PHE A N   1 
ATOM   2603  C  CA  . PHE A 1 375 ? 157.549 157.459 143.583 1.00 38.72  ? 368 PHE A CA  1 
ATOM   2604  C  C   . PHE A 1 375 ? 158.531 157.161 144.705 1.00 38.72  ? 368 PHE A C   1 
ATOM   2605  O  O   . PHE A 1 375 ? 159.746 157.132 144.474 1.00 38.72  ? 368 PHE A O   1 
ATOM   2606  C  CB  . PHE A 1 375 ? 157.643 156.406 142.481 1.00 38.72  ? 368 PHE A CB  1 
ATOM   2607  C  CG  . PHE A 1 375 ? 156.806 155.188 142.721 1.00 38.72  ? 368 PHE A CG  1 
ATOM   2608  C  CD1 . PHE A 1 375 ? 155.430 155.259 142.686 1.00 38.72  ? 368 PHE A CD1 1 
ATOM   2609  C  CD2 . PHE A 1 375 ? 157.398 153.964 142.953 1.00 38.72  ? 368 PHE A CD2 1 
ATOM   2610  C  CE1 . PHE A 1 375 ? 154.664 154.137 142.898 1.00 38.72  ? 368 PHE A CE1 1 
ATOM   2611  C  CE2 . PHE A 1 375 ? 156.641 152.838 143.163 1.00 38.72  ? 368 PHE A CE2 1 
ATOM   2612  C  CZ  . PHE A 1 375 ? 155.271 152.922 143.134 1.00 38.72  ? 368 PHE A CZ  1 
ATOM   2613  N  N   . ASP A 1 376 ? 158.003 156.947 145.907 1.00 46.30  ? 369 ASP A N   1 
ATOM   2614  C  CA  . ASP A 1 376 ? 158.804 156.748 147.108 1.00 46.30  ? 369 ASP A CA  1 
ATOM   2615  C  C   . ASP A 1 376 ? 158.905 155.255 147.393 1.00 46.30  ? 369 ASP A C   1 
ATOM   2616  O  O   . ASP A 1 376 ? 157.884 154.569 147.508 1.00 46.30  ? 369 ASP A O   1 
ATOM   2617  C  CB  . ASP A 1 376 ? 158.185 157.488 148.295 1.00 46.30  ? 369 ASP A CB  1 
ATOM   2618  C  CG  . ASP A 1 376 ? 159.036 157.408 149.553 1.00 46.30  ? 369 ASP A CG  1 
ATOM   2619  O  OD1 . ASP A 1 376 ? 160.175 156.901 149.486 1.00 46.30  ? 369 ASP A OD1 1 
ATOM   2620  O  OD2 . ASP A 1 376 ? 158.561 157.853 150.618 1.00 46.30  ? 369 ASP A OD2 1 
ATOM   2621  N  N   . SER A 1 377 ? 160.133 154.760 147.509 1.00 48.94  ? 370 SER A N   1 
ATOM   2622  C  CA  . SER A 1 377 ? 160.351 153.352 147.786 1.00 48.94  ? 370 SER A CA  1 
ATOM   2623  C  C   . SER A 1 377 ? 159.915 153.010 149.209 1.00 48.94  ? 370 SER A C   1 
ATOM   2624  O  O   . SER A 1 377 ? 159.906 153.873 150.089 1.00 48.94  ? 370 SER A O   1 
ATOM   2625  C  CB  . SER A 1 377 ? 161.823 152.998 147.605 1.00 48.94  ? 370 SER A CB  1 
ATOM   2626  O  OG  . SER A 1 377 ? 162.167 151.845 148.352 1.00 48.94  ? 370 SER A OG  1 
ATOM   2627  N  N   . PRO A 1 378 ? 159.539 151.754 149.458 1.00 51.93  ? 371 PRO A N   1 
ATOM   2628  C  CA  . PRO A 1 378 ? 159.284 151.331 150.843 1.00 51.93  ? 371 PRO A CA  1 
ATOM   2629  C  C   . PRO A 1 378 ? 160.515 151.399 151.729 1.00 51.93  ? 371 PRO A C   1 
ATOM   2630  O  O   . PRO A 1 378 ? 160.372 151.379 152.957 1.00 51.93  ? 371 PRO A O   1 
ATOM   2631  C  CB  . PRO A 1 378 ? 158.780 149.889 150.690 1.00 51.93  ? 371 PRO A CB  1 
ATOM   2632  C  CG  . PRO A 1 378 ? 159.184 149.471 149.319 1.00 51.93  ? 371 PRO A CG  1 
ATOM   2633  C  CD  . PRO A 1 378 ? 159.187 150.708 148.487 1.00 51.93  ? 371 PRO A CD  1 
ATOM   2634  N  N   . ARG A 1 379 ? 161.715 151.456 151.154 1.00 58.73  ? 372 ARG A N   1 
ATOM   2635  C  CA  . ARG A 1 379 ? 162.916 151.666 151.951 1.00 58.73  ? 372 ARG A CA  1 
ATOM   2636  C  C   . ARG A 1 379 ? 162.840 153.012 152.663 1.00 58.73  ? 372 ARG A C   1 
ATOM   2637  O  O   . ARG A 1 379 ? 162.511 154.034 152.054 1.00 58.73  ? 372 ARG A O   1 
ATOM   2638  C  CB  . ARG A 1 379 ? 164.157 151.596 151.062 1.00 58.73  ? 372 ARG A CB  1 
ATOM   2639  C  CG  . ARG A 1 379 ? 165.302 152.476 151.524 1.00 58.73  ? 372 ARG A CG  1 
ATOM   2640  C  CD  . ARG A 1 379 ? 166.263 152.779 150.393 1.00 58.73  ? 372 ARG A CD  1 
ATOM   2641  N  NE  . ARG A 1 379 ? 166.919 154.067 150.580 1.00 58.73  ? 372 ARG A NE  1 
ATOM   2642  C  CZ  . ARG A 1 379 ? 168.213 154.219 150.820 1.00 58.73  ? 372 ARG A CZ  1 
ATOM   2643  N  NH1 . ARG A 1 379 ? 169.025 153.179 150.911 1.00 58.73  ? 372 ARG A NH1 1 
ATOM   2644  N  NH2 . ARG A 1 379 ? 168.705 155.444 150.974 1.00 58.73  ? 372 ARG A NH2 1 
ATOM   2645  N  N   . ASN A 1 380 ? 163.147 153.011 153.958 1.00 61.80  ? 373 ASN A N   1 
ATOM   2646  C  CA  . ASN A 1 380 ? 162.965 154.167 154.833 1.00 61.80  ? 373 ASN A CA  1 
ATOM   2647  C  C   . ASN A 1 380 ? 164.235 154.459 155.620 1.00 61.80  ? 373 ASN A C   1 
ATOM   2648  O  O   . ASN A 1 380 ? 164.228 154.572 156.847 1.00 61.80  ? 373 ASN A O   1 
ATOM   2649  C  CB  . ASN A 1 380 ? 161.782 153.973 155.778 1.00 61.80  ? 373 ASN A CB  1 
ATOM   2650  C  CG  . ASN A 1 380 ? 160.447 153.996 155.060 1.00 61.80  ? 373 ASN A CG  1 
ATOM   2651  O  OD1 . ASN A 1 380 ? 160.383 153.995 153.833 1.00 61.80  ? 373 ASN A OD1 1 
ATOM   2652  N  ND2 . ASN A 1 380 ? 159.368 154.021 155.829 1.00 61.80  ? 373 ASN A ND2 1 
ATOM   2653  N  N   . ARG A 1 381 ? 165.354 154.586 154.915 1.00 65.24  ? 374 ARG A N   1 
ATOM   2654  C  CA  . ARG A 1 381 ? 166.605 154.991 155.540 1.00 65.24  ? 374 ARG A CA  1 
ATOM   2655  C  C   . ARG A 1 381 ? 166.562 156.494 155.821 1.00 65.24  ? 374 ARG A C   1 
ATOM   2656  O  O   . ARG A 1 381 ? 165.502 157.126 155.795 1.00 65.24  ? 374 ARG A O   1 
ATOM   2657  C  CB  . ARG A 1 381 ? 167.791 154.604 154.663 1.00 65.24  ? 374 ARG A CB  1 
ATOM   2658  C  CG  . ARG A 1 381 ? 167.830 153.134 154.292 1.00 65.24  ? 374 ARG A CG  1 
ATOM   2659  C  CD  . ARG A 1 381 ? 168.590 152.324 155.334 1.00 65.24  ? 374 ARG A CD  1 
ATOM   2660  N  NE  . ARG A 1 381 ? 169.081 151.052 154.815 1.00 65.24  ? 374 ARG A NE  1 
ATOM   2661  C  CZ  . ARG A 1 381 ? 169.973 150.921 153.842 1.00 65.24  ? 374 ARG A CZ  1 
ATOM   2662  N  NH1 . ARG A 1 381 ? 170.544 151.973 153.276 1.00 65.24  ? 374 ARG A NH1 1 
ATOM   2663  N  NH2 . ARG A 1 381 ? 170.313 149.702 153.434 1.00 65.24  ? 374 ARG A NH2 1 
ATOM   2664  N  N   . GLY A 1 382 ? 167.726 157.084 156.101 1.00 68.75  ? 375 GLY A N   1 
ATOM   2665  C  CA  . GLY A 1 382 ? 167.793 158.463 156.559 1.00 68.75  ? 375 GLY A CA  1 
ATOM   2666  C  C   . GLY A 1 382 ? 167.183 159.485 155.618 1.00 68.75  ? 375 GLY A C   1 
ATOM   2667  O  O   . GLY A 1 382 ? 166.945 160.625 156.032 1.00 68.75  ? 375 GLY A O   1 
ATOM   2668  N  N   . LEU A 1 383 ? 166.923 159.112 154.363 1.00 63.08  ? 376 LEU A N   1 
ATOM   2669  C  CA  . LEU A 1 383 ? 166.342 160.024 153.385 1.00 63.08  ? 376 LEU A CA  1 
ATOM   2670  C  C   . LEU A 1 383 ? 164.836 159.856 153.238 1.00 63.08  ? 376 LEU A C   1 
ATOM   2671  O  O   . LEU A 1 383 ? 164.306 160.023 152.133 1.00 63.08  ? 376 LEU A O   1 
ATOM   2672  C  CB  . LEU A 1 383 ? 167.021 159.850 152.028 1.00 63.08  ? 376 LEU A CB  1 
ATOM   2673  C  CG  . LEU A 1 383 ? 168.266 160.699 151.789 1.00 63.08  ? 376 LEU A CG  1 
ATOM   2674  C  CD1 . LEU A 1 383 ? 169.117 160.096 150.690 1.00 63.08  ? 376 LEU A CD1 1 
ATOM   2675  C  CD2 . LEU A 1 383 ? 167.874 162.123 151.450 1.00 63.08  ? 376 LEU A CD2 1 
ATOM   2676  N  N   . LYS A 1 384 ? 164.126 159.527 154.317 1.00 57.48  ? 377 LYS A N   1 
ATOM   2677  C  CA  . LYS A 1 384 ? 162.679 159.377 154.224 1.00 57.48  ? 377 LYS A CA  1 
ATOM   2678  C  C   . LYS A 1 384 ? 161.949 160.714 154.254 1.00 57.48  ? 377 LYS A C   1 
ATOM   2679  O  O   . LYS A 1 384 ? 160.735 160.745 154.027 1.00 57.48  ? 377 LYS A O   1 
ATOM   2680  C  CB  . LYS A 1 384 ? 162.171 158.474 155.348 1.00 57.48  ? 377 LYS A CB  1 
ATOM   2681  C  CG  . LYS A 1 384 ? 162.800 158.745 156.702 1.00 57.48  ? 377 LYS A CG  1 
ATOM   2682  C  CD  . LYS A 1 384 ? 162.128 157.929 157.792 1.00 57.48  ? 377 LYS A CD  1 
ATOM   2683  C  CE  . LYS A 1 384 ? 162.889 158.030 159.101 1.00 57.48  ? 377 LYS A CE  1 
ATOM   2684  N  NZ  . LYS A 1 384 ? 162.619 159.318 159.795 1.00 57.48  ? 377 LYS A NZ  1 
ATOM   2685  N  N   . GLU A 1 385 ? 162.653 161.813 154.529 1.00 60.90  ? 378 GLU A N   1 
ATOM   2686  C  CA  . GLU A 1 385 ? 162.022 163.124 154.613 1.00 60.90  ? 378 GLU A CA  1 
ATOM   2687  C  C   . GLU A 1 385 ? 162.189 163.964 153.355 1.00 60.90  ? 378 GLU A C   1 
ATOM   2688  O  O   . GLU A 1 385 ? 161.369 164.859 153.113 1.00 60.90  ? 378 GLU A O   1 
ATOM   2689  C  CB  . GLU A 1 385 ? 162.574 163.901 155.810 1.00 60.90  ? 378 GLU A CB  1 
ATOM   2690  C  CG  . GLU A 1 385 ? 162.199 163.304 157.150 1.00 60.90  ? 378 GLU A CG  1 
ATOM   2691  C  CD  . GLU A 1 385 ? 162.823 164.057 158.308 1.00 60.90  ? 378 GLU A CD  1 
ATOM   2692  O  OE1 . GLU A 1 385 ? 163.691 164.919 158.058 1.00 60.90  ? 378 GLU A OE1 1 
ATOM   2693  O  OE2 . GLU A 1 385 ? 162.442 163.791 159.467 1.00 60.90  ? 378 GLU A OE2 1 
ATOM   2694  N  N   . PHE A 1 386 ? 163.229 163.716 152.562 1.00 54.55  ? 379 PHE A N   1 
ATOM   2695  C  CA  . PHE A 1 386 ? 163.426 164.500 151.344 1.00 54.55  ? 379 PHE A CA  1 
ATOM   2696  C  C   . PHE A 1 386 ? 162.280 164.360 150.350 1.00 54.55  ? 379 PHE A C   1 
ATOM   2697  O  O   . PHE A 1 386 ? 161.709 165.394 149.959 1.00 54.55  ? 379 PHE A O   1 
ATOM   2698  C  CB  . PHE A 1 386 ? 164.771 164.129 150.713 1.00 54.55  ? 379 PHE A CB  1 
ATOM   2699  C  CG  . PHE A 1 386 ? 165.137 164.968 149.526 1.00 54.55  ? 379 PHE A CG  1 
ATOM   2700  C  CD1 . PHE A 1 386 ? 165.493 166.293 149.677 1.00 54.55  ? 379 PHE A CD1 1 
ATOM   2701  C  CD2 . PHE A 1 386 ? 165.134 164.421 148.256 1.00 54.55  ? 379 PHE A CD2 1 
ATOM   2702  C  CE1 . PHE A 1 386 ? 165.837 167.059 148.584 1.00 54.55  ? 379 PHE A CE1 1 
ATOM   2703  C  CE2 . PHE A 1 386 ? 165.475 165.182 147.160 1.00 54.55  ? 379 PHE A CE2 1 
ATOM   2704  C  CZ  . PHE A 1 386 ? 165.827 166.503 147.323 1.00 54.55  ? 379 PHE A CZ  1 
ATOM   2705  N  N   . PRO A 1 387 ? 161.871 163.158 149.921 1.00 49.09  ? 380 PRO A N   1 
ATOM   2706  C  CA  . PRO A 1 387 ? 160.791 163.069 148.928 1.00 49.09  ? 380 PRO A CA  1 
ATOM   2707  C  C   . PRO A 1 387 ? 159.445 163.537 149.439 1.00 49.09  ? 380 PRO A C   1 
ATOM   2708  O  O   . PRO A 1 387 ? 158.561 163.827 148.627 1.00 49.09  ? 380 PRO A O   1 
ATOM   2709  C  CB  . PRO A 1 387 ? 160.751 161.570 148.585 1.00 49.09  ? 380 PRO A CB  1 
ATOM   2710  C  CG  . PRO A 1 387 ? 162.035 161.025 149.076 1.00 49.09  ? 380 PRO A CG  1 
ATOM   2711  C  CD  . PRO A 1 387 ? 162.341 161.816 150.295 1.00 49.09  ? 380 PRO A CD  1 
ATOM   2712  N  N   . ILE A 1 388 ? 159.260 163.632 150.753 1.00 49.47  ? 381 ILE A N   1 
ATOM   2713  C  CA  . ILE A 1 388 ? 157.977 163.995 151.330 1.00 49.47  ? 381 ILE A CA  1 
ATOM   2714  C  C   . ILE A 1 388 ? 157.912 165.468 151.704 1.00 49.47  ? 381 ILE A C   1 
ATOM   2715  O  O   . ILE A 1 388 ? 156.813 166.019 151.817 1.00 49.47  ? 381 ILE A O   1 
ATOM   2716  C  CB  . ILE A 1 388 ? 157.650 163.109 152.551 1.00 49.47  ? 381 ILE A CB  1 
ATOM   2717  C  CG1 . ILE A 1 388 ? 158.683 163.296 153.653 1.00 49.47  ? 381 ILE A CG1 1 
ATOM   2718  C  CG2 . ILE A 1 388 ? 157.589 161.651 152.157 1.00 49.47  ? 381 ILE A CG2 1 
ATOM   2719  C  CD1 . ILE A 1 388 ? 158.198 164.215 154.728 1.00 49.47  ? 381 ILE A CD1 1 
ATOM   2720  N  N   . LYS A 1 389 ? 159.051 166.135 151.853 1.00 51.49  ? 382 LYS A N   1 
ATOM   2721  C  CA  . LYS A 1 389 ? 159.035 167.550 152.211 1.00 51.49  ? 382 LYS A CA  1 
ATOM   2722  C  C   . LYS A 1 389 ? 159.628 168.460 151.145 1.00 51.49  ? 382 LYS A C   1 
ATOM   2723  O  O   . LYS A 1 389 ? 159.040 169.501 150.846 1.00 51.49  ? 382 LYS A O   1 
ATOM   2724  C  CB  . LYS A 1 389 ? 159.782 167.760 153.538 1.00 51.49  ? 382 LYS A CB  1 
ATOM   2725  C  CG  . LYS A 1 389 ? 159.897 169.215 153.970 1.00 51.49  ? 382 LYS A CG  1 
ATOM   2726  C  CD  . LYS A 1 389 ? 158.540 169.891 154.085 1.00 51.49  ? 382 LYS A CD  1 
ATOM   2727  C  CE  . LYS A 1 389 ? 157.972 169.770 155.490 1.00 51.49  ? 382 LYS A CE  1 
ATOM   2728  N  NZ  . LYS A 1 389 ? 157.074 170.913 155.819 1.00 51.49  ? 382 LYS A NZ  1 
ATOM   2729  N  N   . ARG A 1 390 ? 160.769 168.099 150.560 1.00 50.33  ? 383 ARG A N   1 
ATOM   2730  C  CA  . ARG A 1 390 ? 161.492 168.997 149.670 1.00 50.33  ? 383 ARG A CA  1 
ATOM   2731  C  C   . ARG A 1 390 ? 161.248 168.714 148.193 1.00 50.33  ? 383 ARG A C   1 
ATOM   2732  O  O   . ARG A 1 390 ? 161.855 169.374 147.344 1.00 50.33  ? 383 ARG A O   1 
ATOM   2733  C  CB  . ARG A 1 390 ? 162.994 168.931 149.968 1.00 50.33  ? 383 ARG A CB  1 
ATOM   2734  C  CG  . ARG A 1 390 ? 163.772 170.202 149.633 1.00 50.33  ? 383 ARG A CG  1 
ATOM   2735  C  CD  . ARG A 1 390 ? 163.158 171.441 150.268 1.00 50.33  ? 383 ARG A CD  1 
ATOM   2736  N  NE  . ARG A 1 390 ? 163.386 171.498 151.706 1.00 50.33  ? 383 ARG A NE  1 
ATOM   2737  C  CZ  . ARG A 1 390 ? 162.482 171.892 152.593 1.00 50.33  ? 383 ARG A CZ  1 
ATOM   2738  N  NH1 . ARG A 1 390 ? 161.270 172.270 152.222 1.00 50.33  ? 383 ARG A NH1 1 
ATOM   2739  N  NH2 . ARG A 1 390 ? 162.803 171.909 153.883 1.00 50.33  ? 383 ARG A NH2 1 
ATOM   2740  N  N   . VAL A 1 391 ? 160.377 167.764 147.857 1.00 46.48  ? 384 VAL A N   1 
ATOM   2741  C  CA  . VAL A 1 391 ? 160.163 167.412 146.458 1.00 46.48  ? 384 VAL A CA  1 
ATOM   2742  C  C   . VAL A 1 391 ? 158.732 167.734 146.049 1.00 46.48  ? 384 VAL A C   1 
ATOM   2743  O  O   . VAL A 1 391 ? 158.505 168.547 145.146 1.00 46.48  ? 384 VAL A O   1 
ATOM   2744  C  CB  . VAL A 1 391 ? 160.496 165.931 146.204 1.00 46.48  ? 384 VAL A CB  1 
ATOM   2745  C  CG1 . VAL A 1 391 ? 159.789 165.425 144.958 1.00 46.48  ? 384 VAL A CG1 1 
ATOM   2746  C  CG2 . VAL A 1 391 ? 161.994 165.759 146.075 1.00 46.48  ? 384 VAL A CG2 1 
ATOM   2747  N  N   . MET A 1 392 ? 157.775 167.102 146.739 1.00 43.46  ? 385 MET A N   1 
ATOM   2748  C  CA  . MET A 1 392 ? 156.338 167.309 146.418 1.00 43.46  ? 385 MET A CA  1 
ATOM   2749  C  C   . MET A 1 392 ? 155.944 168.744 146.773 1.00 43.46  ? 385 MET A C   1 
ATOM   2750  O  O   . MET A 1 392 ? 156.319 169.204 147.870 1.00 43.46  ? 385 MET A O   1 
ATOM   2751  C  CB  . MET A 1 392 ? 155.447 166.335 147.197 1.00 43.46  ? 385 MET A CB  1 
ATOM   2752  C  CG  . MET A 1 392 ? 153.963 166.605 147.014 1.00 43.46  ? 385 MET A CG  1 
ATOM   2753  S  SD  . MET A 1 392 ? 152.894 165.506 147.975 1.00 43.46  ? 385 MET A SD  1 
ATOM   2754  C  CE  . MET A 1 392 ? 152.258 166.652 149.197 1.00 43.46  ? 385 MET A CE  1 
ATOM   2755  N  N   . GLY A 1 393 ? 155.218 169.414 145.879 1.00 42.88  ? 386 GLY A N   1 
ATOM   2756  C  CA  . GLY A 1 393 ? 154.791 170.772 146.110 1.00 42.88  ? 386 GLY A CA  1 
ATOM   2757  C  C   . GLY A 1 393 ? 153.806 171.241 145.062 1.00 42.88  ? 386 GLY A C   1 
ATOM   2758  O  O   . GLY A 1 393 ? 152.888 170.516 144.671 1.00 42.88  ? 386 GLY A O   1 
ATOM   2759  N  N   . PRO A 1 394 ? 153.969 172.478 144.595 1.00 41.52  ? 387 PRO A N   1 
ATOM   2760  C  CA  . PRO A 1 394 ? 153.135 172.968 143.489 1.00 41.52  ? 387 PRO A CA  1 
ATOM   2761  C  C   . PRO A 1 394 ? 153.496 172.246 142.199 1.00 41.52  ? 387 PRO A C   1 
ATOM   2762  O  O   . PRO A 1 394 ? 154.632 172.330 141.728 1.00 41.52  ? 387 PRO A O   1 
ATOM   2763  C  CB  . PRO A 1 394 ? 153.474 174.463 143.418 1.00 41.52  ? 387 PRO A CB  1 
ATOM   2764  C  CG  . PRO A 1 394 ? 154.152 174.778 144.716 1.00 41.52  ? 387 PRO A CG  1 
ATOM   2765  C  CD  . PRO A 1 394 ? 154.853 173.526 145.124 1.00 41.52  ? 387 PRO A CD  1 
ATOM   2766  N  N   . ASP A 1 395 ? 152.520 171.532 141.635 1.00 39.80  ? 388 ASP A N   1 
ATOM   2767  C  CA  . ASP A 1 395 ? 152.700 170.779 140.393 1.00 39.80  ? 388 ASP A CA  1 
ATOM   2768  C  C   . ASP A 1 395 ? 153.815 169.745 140.526 1.00 39.80  ? 388 ASP A C   1 
ATOM   2769  O  O   . ASP A 1 395 ? 154.756 169.704 139.732 1.00 39.80  ? 388 ASP A O   1 
ATOM   2770  C  CB  . ASP A 1 395 ? 152.962 171.717 139.215 1.00 39.80  ? 388 ASP A CB  1 
ATOM   2771  C  CG  . ASP A 1 395 ? 151.692 172.158 138.532 1.00 39.80  ? 388 ASP A CG  1 
ATOM   2772  O  OD1 . ASP A 1 395 ? 150.708 172.460 139.239 1.00 39.80  ? 388 ASP A OD1 1 
ATOM   2773  O  OD2 . ASP A 1 395 ? 151.679 172.204 137.286 1.00 39.80  ? 388 ASP A OD2 1 
ATOM   2774  N  N   . PHE A 1 396 ? 153.708 168.910 141.558 1.00 35.52  ? 389 PHE A N   1 
ATOM   2775  C  CA  . PHE A 1 396 ? 154.642 167.803 141.754 1.00 35.52  ? 389 PHE A CA  1 
ATOM   2776  C  C   . PHE A 1 396 ? 153.929 166.768 142.618 1.00 35.52  ? 389 PHE A C   1 
ATOM   2777  O  O   . PHE A 1 396 ? 153.893 166.904 143.844 1.00 35.52  ? 389 PHE A O   1 
ATOM   2778  C  CB  . PHE A 1 396 ? 155.931 168.282 142.404 1.00 35.52  ? 389 PHE A CB  1 
ATOM   2779  C  CG  . PHE A 1 396 ? 157.172 167.683 141.811 1.00 35.52  ? 389 PHE A CG  1 
ATOM   2780  C  CD1 . PHE A 1 396 ? 157.253 166.326 141.564 1.00 35.52  ? 389 PHE A CD1 1 
ATOM   2781  C  CD2 . PHE A 1 396 ? 158.267 168.477 141.523 1.00 35.52  ? 389 PHE A CD2 1 
ATOM   2782  C  CE1 . PHE A 1 396 ? 158.399 165.774 141.028 1.00 35.52  ? 389 PHE A CE1 1 
ATOM   2783  C  CE2 . PHE A 1 396 ? 159.413 167.930 140.989 1.00 35.52  ? 389 PHE A CE2 1 
ATOM   2784  C  CZ  . PHE A 1 396 ? 159.479 166.576 140.741 1.00 35.52  ? 389 PHE A CZ  1 
ATOM   2785  N  N   . GLY A 1 397 ? 153.377 165.741 141.982 1.00 35.29  ? 390 GLY A N   1 
ATOM   2786  C  CA  . GLY A 1 397 ? 152.635 164.728 142.698 1.00 35.29  ? 390 GLY A CA  1 
ATOM   2787  C  C   . GLY A 1 397 ? 153.535 163.754 143.432 1.00 35.29  ? 390 GLY A C   1 
ATOM   2788  O  O   . GLY A 1 397 ? 154.743 163.682 143.218 1.00 35.29  ? 390 GLY A O   1 
ATOM   2789  N  N   . TYR A 1 398 ? 152.914 162.965 144.306 1.00 38.29  ? 391 TYR A N   1 
ATOM   2790  C  CA  . TYR A 1 398 ? 153.656 162.000 145.115 1.00 38.29  ? 391 TYR A CA  1 
ATOM   2791  C  C   . TYR A 1 398 ? 152.786 160.762 145.269 1.00 38.29  ? 391 TYR A C   1 
ATOM   2792  O  O   . TYR A 1 398 ? 151.638 160.870 145.709 1.00 38.29  ? 391 TYR A O   1 
ATOM   2793  C  CB  . TYR A 1 398 ? 154.016 162.601 146.470 1.00 38.29  ? 391 TYR A CB  1 
ATOM   2794  C  CG  . TYR A 1 398 ? 154.437 161.602 147.528 1.00 38.29  ? 391 TYR A CG  1 
ATOM   2795  C  CD1 . TYR A 1 398 ? 155.779 161.355 147.777 1.00 38.29  ? 391 TYR A CD1 1 
ATOM   2796  C  CD2 . TYR A 1 398 ? 153.496 160.933 148.302 1.00 38.29  ? 391 TYR A CD2 1 
ATOM   2797  C  CE1 . TYR A 1 398 ? 156.172 160.454 148.743 1.00 38.29  ? 391 TYR A CE1 1 
ATOM   2798  C  CE2 . TYR A 1 398 ? 153.881 160.030 149.267 1.00 38.29  ? 391 TYR A CE2 1 
ATOM   2799  C  CZ  . TYR A 1 398 ? 155.219 159.796 149.485 1.00 38.29  ? 391 TYR A CZ  1 
ATOM   2800  O  OH  . TYR A 1 398 ? 155.608 158.898 150.449 1.00 38.29  ? 391 TYR A OH  1 
ATOM   2801  N  N   . VAL A 1 399 ? 153.323 159.597 144.916 1.00 37.82  ? 392 VAL A N   1 
ATOM   2802  C  CA  . VAL A 1 399 ? 152.610 158.337 145.091 1.00 37.82  ? 392 VAL A CA  1 
ATOM   2803  C  C   . VAL A 1 399 ? 153.604 157.259 145.497 1.00 37.82  ? 392 VAL A C   1 
ATOM   2804  O  O   . VAL A 1 399 ? 154.752 157.262 145.041 1.00 37.82  ? 392 VAL A O   1 
ATOM   2805  C  CB  . VAL A 1 399 ? 151.832 157.937 143.822 1.00 37.82  ? 392 VAL A CB  1 
ATOM   2806  C  CG1 . VAL A 1 399 ? 152.750 157.343 142.776 1.00 37.82  ? 392 VAL A CG1 1 
ATOM   2807  C  CG2 . VAL A 1 399 ? 150.727 156.964 144.175 1.00 37.82  ? 392 VAL A CG2 1 
ATOM   2808  N  N   . THR A 1 400 ? 153.175 156.361 146.383 1.00 41.07  ? 393 THR A N   1 
ATOM   2809  C  CA  . THR A 1 400 ? 154.016 155.286 146.887 1.00 41.07  ? 393 THR A CA  1 
ATOM   2810  C  C   . THR A 1 400 ? 153.163 154.060 147.175 1.00 41.07  ? 393 THR A C   1 
ATOM   2811  O  O   . THR A 1 400 ? 151.953 154.165 147.386 1.00 41.07  ? 393 THR A O   1 
ATOM   2812  C  CB  . THR A 1 400 ? 154.761 155.698 148.159 1.00 41.07  ? 393 THR A CB  1 
ATOM   2813  O  OG1 . THR A 1 400 ? 155.333 154.537 148.772 1.00 41.07  ? 393 THR A OG1 1 
ATOM   2814  C  CG2 . THR A 1 400 ? 153.809 156.361 149.136 1.00 41.07  ? 393 THR A CG2 1 
ATOM   2815  N  N   . ARG A 1 401 ? 153.809 152.894 147.190 1.00 41.42  ? 394 ARG A N   1 
ATOM   2816  C  CA  . ARG A 1 401 ? 153.123 151.629 147.410 1.00 41.42  ? 394 ARG A CA  1 
ATOM   2817  C  C   . ARG A 1 401 ? 153.999 150.705 148.243 1.00 41.42  ? 394 ARG A C   1 
ATOM   2818  O  O   . ARG A 1 401 ? 155.227 150.816 148.237 1.00 41.42  ? 394 ARG A O   1 
ATOM   2819  C  CB  . ARG A 1 401 ? 152.765 150.947 146.083 1.00 41.42  ? 394 ARG A CB  1 
ATOM   2820  C  CG  . ARG A 1 401 ? 151.587 151.572 145.363 1.00 41.42  ? 394 ARG A CG  1 
ATOM   2821  C  CD  . ARG A 1 401 ? 150.379 151.659 146.275 1.00 41.42  ? 394 ARG A CD  1 
ATOM   2822  N  NE  . ARG A 1 401 ? 149.149 151.251 145.609 1.00 41.42  ? 394 ARG A NE  1 
ATOM   2823  C  CZ  . ARG A 1 401 ? 148.496 151.990 144.723 1.00 41.42  ? 394 ARG A CZ  1 
ATOM   2824  N  NH1 . ARG A 1 401 ? 148.925 153.192 144.377 1.00 41.42  ? 394 ARG A NH1 1 
ATOM   2825  N  NH2 . ARG A 1 401 ? 147.383 151.513 144.176 1.00 41.42  ? 394 ARG A NH2 1 
ATOM   2826  N  N   . GLY A 1 402 ? 153.353 149.790 148.963 1.00 48.96  ? 395 GLY A N   1 
ATOM   2827  C  CA  . GLY A 1 402 ? 154.054 148.768 149.703 1.00 48.96  ? 395 GLY A CA  1 
ATOM   2828  C  C   . GLY A 1 402 ? 153.953 148.936 151.205 1.00 48.96  ? 395 GLY A C   1 
ATOM   2829  O  O   . GLY A 1 402 ? 153.317 149.866 151.711 1.00 48.96  ? 395 GLY A O   1 
ATOM   2830  N  N   . PRO A 1 403 ? 154.579 148.021 151.954 1.00 53.33  ? 396 PRO A N   1 
ATOM   2831  C  CA  . PRO A 1 403 ? 154.605 148.152 153.415 1.00 53.33  ? 396 PRO A CA  1 
ATOM   2832  C  C   . PRO A 1 403 ? 155.749 149.034 153.886 1.00 53.33  ? 396 PRO A C   1 
ATOM   2833  O  O   . PRO A 1 403 ? 156.905 148.815 153.510 1.00 53.33  ? 396 PRO A O   1 
ATOM   2834  C  CB  . PRO A 1 403 ? 154.776 146.705 153.886 1.00 53.33  ? 396 PRO A CB  1 
ATOM   2835  C  CG  . PRO A 1 403 ? 155.559 146.058 152.789 1.00 53.33  ? 396 PRO A CG  1 
ATOM   2836  C  CD  . PRO A 1 403 ? 155.251 146.792 151.500 1.00 53.33  ? 396 PRO A CD  1 
ATOM   2837  N  N   . GLN A 1 404 ? 155.442 150.033 154.709 1.00 58.65  ? 397 GLN A N   1 
ATOM   2838  C  CA  . GLN A 1 404 ? 156.446 151.003 155.126 1.00 58.65  ? 397 GLN A CA  1 
ATOM   2839  C  C   . GLN A 1 404 ? 157.159 150.613 156.413 1.00 58.65  ? 397 GLN A C   1 
ATOM   2840  O  O   . GLN A 1 404 ? 158.326 150.977 156.598 1.00 58.65  ? 397 GLN A O   1 
ATOM   2841  C  CB  . GLN A 1 404 ? 155.802 152.380 155.299 1.00 58.65  ? 397 GLN A CB  1 
ATOM   2842  C  CG  . GLN A 1 404 ? 154.809 152.730 154.206 1.00 58.65  ? 397 GLN A CG  1 
ATOM   2843  C  CD  . GLN A 1 404 ? 155.431 153.555 153.101 1.00 58.65  ? 397 GLN A CD  1 
ATOM   2844  O  OE1 . GLN A 1 404 ? 156.546 154.054 153.238 1.00 58.65  ? 397 GLN A OE1 1 
ATOM   2845  N  NE2 . GLN A 1 404 ? 154.711 153.702 151.996 1.00 58.65  ? 397 GLN A NE2 1 
ATOM   2846  N  N   . THR A 1 405 ? 156.494 149.884 157.304 1.00 66.15  ? 398 THR A N   1 
ATOM   2847  C  CA  . THR A 1 405 ? 157.067 149.538 158.605 1.00 66.15  ? 398 THR A CA  1 
ATOM   2848  C  C   . THR A 1 405 ? 157.883 148.248 158.548 1.00 66.15  ? 398 THR A C   1 
ATOM   2849  O  O   . THR A 1 405 ? 157.683 147.322 159.333 1.00 66.15  ? 398 THR A O   1 
ATOM   2850  C  CB  . THR A 1 405 ? 155.958 149.442 159.647 1.00 66.15  ? 398 THR A CB  1 
ATOM   2851  O  OG1 . THR A 1 405 ? 156.483 148.886 160.860 1.00 66.15  ? 398 THR A OG1 1 
ATOM   2852  C  CG2 . THR A 1 405 ? 154.809 148.577 159.138 1.00 66.15  ? 398 THR A CG2 1 
ATOM   2853  N  N   . GLY A 1 406 ? 158.826 148.186 157.617 1.00 65.57  ? 399 GLY A N   1 
ATOM   2854  C  CA  . GLY A 1 406 ? 159.704 147.043 157.498 1.00 65.57  ? 399 GLY A CA  1 
ATOM   2855  C  C   . GLY A 1 406 ? 159.061 145.884 156.756 1.00 65.57  ? 399 GLY A C   1 
ATOM   2856  O  O   . GLY A 1 406 ? 157.858 145.851 156.500 1.00 65.57  ? 399 GLY A O   1 
ATOM   2857  N  N   . GLY A 1 407 ? 159.896 144.909 156.409 1.00 62.72  ? 400 GLY A N   1 
ATOM   2858  C  CA  . GLY A 1 407 ? 159.431 143.736 155.696 1.00 62.72  ? 400 GLY A CA  1 
ATOM   2859  C  C   . GLY A 1 407 ? 159.828 143.736 154.235 1.00 62.72  ? 400 GLY A C   1 
ATOM   2860  O  O   . GLY A 1 407 ? 159.132 143.161 153.394 1.00 62.72  ? 400 GLY A O   1 
ATOM   2861  N  N   . ILE A 1 408 ? 160.951 144.380 153.923 1.00 54.57  ? 401 ILE A N   1 
ATOM   2862  C  CA  . ILE A 1 408 ? 161.429 144.486 152.549 1.00 54.57  ? 401 ILE A CA  1 
ATOM   2863  C  C   . ILE A 1 408 ? 162.854 143.960 152.465 1.00 54.57  ? 401 ILE A C   1 
ATOM   2864  O  O   . ILE A 1 408 ? 163.428 143.521 153.468 1.00 54.57  ? 401 ILE A O   1 
ATOM   2865  C  CB  . ILE A 1 408 ? 161.350 145.938 152.046 1.00 54.57  ? 401 ILE A CB  1 
ATOM   2866  C  CG1 . ILE A 1 408 ? 162.261 146.834 152.886 1.00 54.57  ? 401 ILE A CG1 1 
ATOM   2867  C  CG2 . ILE A 1 408 ? 159.914 146.432 152.075 1.00 54.57  ? 401 ILE A CG2 1 
ATOM   2868  C  CD1 . ILE A 1 408 ? 161.920 148.301 152.807 1.00 54.57  ? 401 ILE A CD1 1 
ATOM   2869  N  N   . SER A 1 409 ? 163.434 144.003 151.267 1.00 50.69  ? 402 SER A N   1 
ATOM   2870  C  CA  . SER A 1 409 ? 164.798 143.551 151.041 1.00 50.69  ? 402 SER A CA  1 
ATOM   2871  C  C   . SER A 1 409 ? 165.497 144.552 150.131 1.00 50.69  ? 402 SER A C   1 
ATOM   2872  O  O   . SER A 1 409 ? 164.885 145.498 149.626 1.00 50.69  ? 402 SER A O   1 
ATOM   2873  C  CB  . SER A 1 409 ? 164.823 142.142 150.441 1.00 50.69  ? 402 SER A CB  1 
ATOM   2874  O  OG  . SER A 1 409 ? 163.716 141.937 149.582 1.00 50.69  ? 402 SER A OG  1 
ATOM   2875  N  N   . GLY A 1 410 ? 166.796 144.334 149.918 1.00 49.41  ? 403 GLY A N   1 
ATOM   2876  C  CA  . GLY A 1 410 ? 167.571 145.257 149.107 1.00 49.41  ? 403 GLY A CA  1 
ATOM   2877  C  C   . GLY A 1 410 ? 167.038 145.407 147.697 1.00 49.41  ? 403 GLY A C   1 
ATOM   2878  O  O   . GLY A 1 410 ? 167.186 146.467 147.083 1.00 49.41  ? 403 GLY A O   1 
ATOM   2879  N  N   . LEU A 1 411 ? 166.394 144.363 147.172 1.00 46.41  ? 404 LEU A N   1 
ATOM   2880  C  CA  . LEU A 1 411 ? 165.838 144.433 145.827 1.00 46.41  ? 404 LEU A CA  1 
ATOM   2881  C  C   . LEU A 1 411 ? 164.745 145.485 145.709 1.00 46.41  ? 404 LEU A C   1 
ATOM   2882  O  O   . LEU A 1 411 ? 164.393 145.871 144.590 1.00 46.41  ? 404 LEU A O   1 
ATOM   2883  C  CB  . LEU A 1 411 ? 165.292 143.068 145.408 1.00 46.41  ? 404 LEU A CB  1 
ATOM   2884  C  CG  . LEU A 1 411 ? 166.184 142.235 144.488 1.00 46.41  ? 404 LEU A CG  1 
ATOM   2885  C  CD1 . LEU A 1 411 ? 167.580 142.100 145.063 1.00 46.41  ? 404 LEU A CD1 1 
ATOM   2886  C  CD2 . LEU A 1 411 ? 165.569 140.871 144.256 1.00 46.41  ? 404 LEU A CD2 1 
ATOM   2887  N  N   . ASP A 1 412 ? 164.200 145.954 146.830 1.00 48.82  ? 405 ASP A N   1 
ATOM   2888  C  CA  . ASP A 1 412 ? 163.214 147.024 146.793 1.00 48.82  ? 405 ASP A CA  1 
ATOM   2889  C  C   . ASP A 1 412 ? 163.835 148.397 146.584 1.00 48.82  ? 405 ASP A C   1 
ATOM   2890  O  O   . ASP A 1 412 ? 163.106 149.342 146.268 1.00 48.82  ? 405 ASP A O   1 
ATOM   2891  C  CB  . ASP A 1 412 ? 162.391 147.023 148.080 1.00 48.82  ? 405 ASP A CB  1 
ATOM   2892  C  CG  . ASP A 1 412 ? 161.282 145.997 148.054 1.00 48.82  ? 405 ASP A CG  1 
ATOM   2893  O  OD1 . ASP A 1 412 ? 160.441 146.060 147.135 1.00 48.82  ? 405 ASP A OD1 1 
ATOM   2894  O  OD2 . ASP A 1 412 ? 161.255 145.124 148.946 1.00 48.82  ? 405 ASP A OD2 1 
ATOM   2895  N  N   . SER A 1 413 ? 165.160 148.499 146.734 1.00 47.21  ? 406 SER A N   1 
ATOM   2896  C  CA  . SER A 1 413 ? 165.832 149.786 146.416 1.00 47.21  ? 406 SER A CA  1 
ATOM   2897  C  C   . SER A 1 413 ? 165.592 150.074 144.932 1.00 47.21  ? 406 SER A C   1 
ATOM   2898  O  O   . SER A 1 413 ? 165.489 149.101 144.157 1.00 47.21  ? 406 SER A O   1 
ATOM   2899  C  CB  . SER A 1 413 ? 167.296 149.744 146.750 1.00 47.21  ? 406 SER A CB  1 
ATOM   2900  O  OG  . SER A 1 413 ? 167.490 149.445 148.124 1.00 47.21  ? 406 SER A OG  1 
ATOM   2901  N  N   . PHE A 1 414 ? 165.483 151.348 144.552 1.00 41.61  ? 407 PHE A N   1 
ATOM   2902  C  CA  . PHE A 1 414 ? 165.139 151.673 143.141 1.00 41.61  ? 407 PHE A CA  1 
ATOM   2903  C  C   . PHE A 1 414 ? 166.313 151.326 142.220 1.00 41.61  ? 407 PHE A C   1 
ATOM   2904  O  O   . PHE A 1 414 ? 166.312 151.782 141.060 1.00 41.61  ? 407 PHE A O   1 
ATOM   2905  C  CB  . PHE A 1 414 ? 164.654 153.121 143.039 1.00 41.61  ? 407 PHE A CB  1 
ATOM   2906  C  CG  . PHE A 1 414 ? 163.216 153.283 143.457 1.00 41.61  ? 407 PHE A CG  1 
ATOM   2907  C  CD1 . PHE A 1 414 ? 162.441 152.173 143.757 1.00 41.61  ? 407 PHE A CD1 1 
ATOM   2908  C  CD2 . PHE A 1 414 ? 162.639 154.535 143.569 1.00 41.61  ? 407 PHE A CD2 1 
ATOM   2909  C  CE1 . PHE A 1 414 ? 161.118 152.312 144.142 1.00 41.61  ? 407 PHE A CE1 1 
ATOM   2910  C  CE2 . PHE A 1 414 ? 161.316 154.672 143.957 1.00 41.61  ? 407 PHE A CE2 1 
ATOM   2911  C  CZ  . PHE A 1 414 ? 160.558 153.562 144.242 1.00 41.61  ? 407 PHE A CZ  1 
ATOM   2912  N  N   . GLY A 1 415 ? 167.276 150.542 142.715 1.00 45.85  ? 408 GLY A N   1 
ATOM   2913  C  CA  . GLY A 1 415 ? 168.368 150.078 141.838 1.00 45.85  ? 408 GLY A CA  1 
ATOM   2914  C  C   . GLY A 1 415 ? 167.802 149.165 140.766 1.00 45.85  ? 408 GLY A C   1 
ATOM   2915  O  O   . GLY A 1 415 ? 168.277 149.240 139.616 1.00 45.85  ? 408 GLY A O   1 
ATOM   2916  N  N   . ASN A 1 416 ? 166.822 148.331 141.130 1.00 41.69  ? 409 ASN A N   1 
ATOM   2917  C  CA  . ASN A 1 416 ? 166.142 147.457 140.138 1.00 41.69  ? 409 ASN A CA  1 
ATOM   2918  C  C   . ASN A 1 416 ? 164.931 148.206 139.575 1.00 41.69  ? 409 ASN A C   1 
ATOM   2919  O  O   . ASN A 1 416 ? 163.797 147.772 139.846 1.00 41.69  ? 409 ASN A O   1 
ATOM   2920  C  CB  . ASN A 1 416 ? 165.704 146.128 140.756 1.00 41.69  ? 409 ASN A CB  1 
ATOM   2921  C  CG  . ASN A 1 416 ? 166.847 145.155 140.950 1.00 41.69  ? 409 ASN A CG  1 
ATOM   2922  O  OD1 . ASN A 1 416 ? 167.970 145.423 140.533 1.00 41.69  ? 409 ASN A OD1 1 
ATOM   2923  N  ND2 . ASN A 1 416 ? 166.568 144.018 141.564 1.00 41.69  ? 409 ASN A ND2 1 
ATOM   2924  N  N   . LEU A 1 417 ? 165.166 149.296 138.839 1.00 36.69  ? 410 LEU A N   1 
ATOM   2925  C  CA  . LEU A 1 417 ? 164.052 150.095 138.262 1.00 36.69  ? 410 LEU A CA  1 
ATOM   2926  C  C   . LEU A 1 417 ? 164.594 150.972 137.131 1.00 36.69  ? 410 LEU A C   1 
ATOM   2927  O  O   . LEU A 1 417 ? 165.009 152.112 137.417 1.00 36.69  ? 410 LEU A O   1 
ATOM   2928  C  CB  . LEU A 1 417 ? 163.417 150.944 139.368 1.00 36.69  ? 410 LEU A CB  1 
ATOM   2929  C  CG  . LEU A 1 417 ? 162.088 151.603 139.001 1.00 36.69  ? 410 LEU A CG  1 
ATOM   2930  C  CD1 . LEU A 1 417 ? 161.058 150.554 138.614 1.00 36.69  ? 410 LEU A CD1 1 
ATOM   2931  C  CD2 . LEU A 1 417 ? 161.570 152.451 140.152 1.00 36.69  ? 410 LEU A CD2 1 
ATOM   2932  N  N   . GLU A 1 418 ? 164.593 150.453 135.899 1.00 36.36  ? 411 GLU A N   1 
ATOM   2933  C  CA  . GLU A 1 418 ? 165.095 151.209 134.763 1.00 36.36  ? 411 GLU A CA  1 
ATOM   2934  C  C   . GLU A 1 418 ? 164.085 151.121 133.630 1.00 36.36  ? 411 GLU A C   1 
ATOM   2935  O  O   . GLU A 1 418 ? 163.134 150.341 133.680 1.00 36.36  ? 411 GLU A O   1 
ATOM   2936  C  CB  . GLU A 1 418 ? 166.467 150.697 134.311 1.00 36.36  ? 411 GLU A CB  1 
ATOM   2937  C  CG  . GLU A 1 418 ? 167.546 150.851 135.365 1.00 36.36  ? 411 GLU A CG  1 
ATOM   2938  C  CD  . GLU A 1 418 ? 168.089 152.265 135.441 1.00 36.36  ? 411 GLU A CD  1 
ATOM   2939  O  OE1 . GLU A 1 418 ? 168.290 152.886 134.377 1.00 36.36  ? 411 GLU A OE1 1 
ATOM   2940  O  OE2 . GLU A 1 418 ? 168.309 152.757 136.567 1.00 36.36  ? 411 GLU A OE2 1 
ATOM   2941  N  N   . VAL A 1 419 ? 164.274 151.950 132.607 1.00 29.84  ? 412 VAL A N   1 
ATOM   2942  C  CA  . VAL A 1 419 ? 163.393 151.951 131.446 1.00 29.84  ? 412 VAL A CA  1 
ATOM   2943  C  C   . VAL A 1 419 ? 164.236 152.000 130.183 1.00 29.84  ? 412 VAL A C   1 
ATOM   2944  O  O   . VAL A 1 419 ? 165.202 152.764 130.096 1.00 29.84  ? 412 VAL A O   1 
ATOM   2945  C  CB  . VAL A 1 419 ? 162.400 153.129 131.471 1.00 29.84  ? 412 VAL A CB  1 
ATOM   2946  C  CG1 . VAL A 1 419 ? 161.418 153.010 130.327 1.00 29.84  ? 412 VAL A CG1 1 
ATOM   2947  C  CG2 . VAL A 1 419 ? 161.663 153.157 132.776 1.00 29.84  ? 412 VAL A CG2 1 
ATOM   2948  N  N   . SER A 1 420 ? 163.849 151.191 129.192 1.00 30.72  ? 413 SER A N   1 
ATOM   2949  C  CA  . SER A 1 420 ? 164.546 151.215 127.882 1.00 30.72  ? 413 SER A CA  1 
ATOM   2950  C  C   . SER A 1 420 ? 163.872 152.260 126.988 1.00 30.72  ? 413 SER A C   1 
ATOM   2951  O  O   . SER A 1 420 ? 162.694 152.575 127.240 1.00 30.72  ? 413 SER A O   1 
ATOM   2952  C  CB  . SER A 1 420 ? 164.515 149.855 127.242 1.00 30.72  ? 413 SER A CB  1 
ATOM   2953  O  OG  . SER A 1 420 ? 163.178 149.451 126.985 1.00 30.72  ? 413 SER A OG  1 
ATOM   2954  N  N   . PRO A 1 421 ? 164.554 152.817 125.963 1.00 33.44  ? 414 PRO A N   1 
ATOM   2955  C  CA  . PRO A 1 421 ? 163.922 153.759 125.032 1.00 33.44  ? 414 PRO A CA  1 
ATOM   2956  C  C   . PRO A 1 421 ? 162.866 153.050 124.169 1.00 33.44  ? 414 PRO A C   1 
ATOM   2957  O  O   . PRO A 1 421 ? 162.826 151.833 124.178 1.00 33.44  ? 414 PRO A O   1 
ATOM   2958  C  CB  . PRO A 1 421 ? 165.092 154.239 124.159 1.00 33.44  ? 414 PRO A CB  1 
ATOM   2959  C  CG  . PRO A 1 421 ? 166.323 153.912 124.974 1.00 33.44  ? 414 PRO A CG  1 
ATOM   2960  C  CD  . PRO A 1 421 ? 165.972 152.618 125.673 1.00 33.44  ? 414 PRO A CD  1 
ATOM   2961  N  N   . PRO A 1 422 ? 162.010 153.784 123.421 1.00 32.62  ? 415 PRO A N   1 
ATOM   2962  C  CA  . PRO A 1 422 ? 161.000 153.171 122.554 1.00 32.62  ? 415 PRO A CA  1 
ATOM   2963  C  C   . PRO A 1 422 ? 161.588 152.009 121.739 1.00 32.62  ? 415 PRO A C   1 
ATOM   2964  O  O   . PRO A 1 422 ? 162.650 152.183 121.168 1.00 32.62  ? 415 PRO A O   1 
ATOM   2965  C  CB  . PRO A 1 422 ? 160.563 154.307 121.613 1.00 32.62  ? 415 PRO A CB  1 
ATOM   2966  C  CG  . PRO A 1 422 ? 161.462 155.483 121.954 1.00 32.62  ? 415 PRO A CG  1 
ATOM   2967  C  CD  . PRO A 1 422 ? 161.940 155.242 123.369 1.00 32.62  ? 415 PRO A CD  1 
ATOM   2968  N  N   . VAL A 1 423 ? 160.889 150.867 121.694 1.00 34.75  ? 416 VAL A N   1 
ATOM   2969  C  CA  . VAL A 1 423 ? 161.451 149.666 121.004 1.00 34.75  ? 416 VAL A CA  1 
ATOM   2970  C  C   . VAL A 1 423 ? 160.391 148.987 120.130 1.00 34.75  ? 416 VAL A C   1 
ATOM   2971  O  O   . VAL A 1 423 ? 159.190 149.161 120.418 1.00 34.75  ? 416 VAL A O   1 
ATOM   2972  C  CB  . VAL A 1 423 ? 162.035 148.665 122.022 1.00 34.75  ? 416 VAL A CB  1 
ATOM   2973  C  CG1 . VAL A 1 423 ? 163.420 149.073 122.501 1.00 34.75  ? 416 VAL A CG1 1 
ATOM   2974  C  CG2 . VAL A 1 423 ? 161.097 148.443 123.199 1.00 34.75  ? 416 VAL A CG2 1 
ATOM   2975  N  N   . THR A 1 424 ? 160.825 148.246 119.105 1.00 41.09  ? 417 THR A N   1 
ATOM   2976  C  CA  . THR A 1 424 ? 159.918 147.495 118.240 1.00 41.09  ? 417 THR A CA  1 
ATOM   2977  C  C   . THR A 1 424 ? 160.359 146.039 118.274 1.00 41.09  ? 417 THR A C   1 
ATOM   2978  O  O   . THR A 1 424 ? 161.450 145.712 117.797 1.00 41.09  ? 417 THR A O   1 
ATOM   2979  C  CB  . THR A 1 424 ? 159.933 148.026 116.806 1.00 41.09  ? 417 THR A CB  1 
ATOM   2980  O  OG1 . THR A 1 424 ? 159.504 149.392 116.799 1.00 41.09  ? 417 THR A OG1 1 
ATOM   2981  C  CG2 . THR A 1 424 ? 159.011 147.212 115.918 1.00 41.09  ? 417 THR A CG2 1 
ATOM   2982  N  N   . VAL A 1 425 ? 159.523 145.167 118.831 1.00 44.54  ? 418 VAL A N   1 
ATOM   2983  C  CA  . VAL A 1 425 ? 159.836 143.748 118.952 1.00 44.54  ? 418 VAL A CA  1 
ATOM   2984  C  C   . VAL A 1 425 ? 158.855 142.953 118.099 1.00 44.54  ? 418 VAL A C   1 
ATOM   2985  O  O   . VAL A 1 425 ? 157.644 142.961 118.352 1.00 44.54  ? 418 VAL A O   1 
ATOM   2986  C  CB  . VAL A 1 425 ? 159.822 143.283 120.418 1.00 44.54  ? 418 VAL A CB  1 
ATOM   2987  C  CG1 . VAL A 1 425 ? 160.936 143.954 121.181 1.00 44.54  ? 418 VAL A CG1 1 
ATOM   2988  C  CG2 . VAL A 1 425 ? 158.501 143.604 121.089 1.00 44.54  ? 418 VAL A CG2 1 
ATOM   2989  N  N   . ARG A 1 426 ? 159.384 142.287 117.071 1.00 50.72  ? 419 ARG A N   1 
ATOM   2990  C  CA  . ARG A 1 426 ? 158.619 141.345 116.252 1.00 50.72  ? 419 ARG A CA  1 
ATOM   2991  C  C   . ARG A 1 426 ? 157.314 141.959 115.748 1.00 50.72  ? 419 ARG A C   1 
ATOM   2992  O  O   . ARG A 1 426 ? 156.259 141.322 115.753 1.00 50.72  ? 419 ARG A O   1 
ATOM   2993  C  CB  . ARG A 1 426 ? 158.357 140.052 117.024 1.00 50.72  ? 419 ARG A CB  1 
ATOM   2994  C  CG  . ARG A 1 426 ? 159.604 139.469 117.672 1.00 50.72  ? 419 ARG A CG  1 
ATOM   2995  C  CD  . ARG A 1 426 ? 159.273 138.324 118.614 1.00 50.72  ? 419 ARG A CD  1 
ATOM   2996  N  NE  . ARG A 1 426 ? 158.233 138.684 119.570 1.00 50.72  ? 419 ARG A NE  1 
ATOM   2997  C  CZ  . ARG A 1 426 ? 158.261 138.372 120.859 1.00 50.72  ? 419 ARG A CZ  1 
ATOM   2998  N  NH1 . ARG A 1 426 ? 159.269 137.696 121.384 1.00 50.72  ? 419 ARG A NH1 1 
ATOM   2999  N  NH2 . ARG A 1 426 ? 157.253 138.750 121.640 1.00 50.72  ? 419 ARG A NH2 1 
ATOM   3000  N  N   . GLY A 1 427 ? 157.387 143.217 115.313 1.00 50.66  ? 420 GLY A N   1 
ATOM   3001  C  CA  . GLY A 1 427 ? 156.247 143.897 114.739 1.00 50.66  ? 420 GLY A CA  1 
ATOM   3002  C  C   . GLY A 1 427 ? 155.372 144.656 115.714 1.00 50.66  ? 420 GLY A C   1 
ATOM   3003  O  O   . GLY A 1 427 ? 154.429 145.327 115.277 1.00 50.66  ? 420 GLY A O   1 
ATOM   3004  N  N   . LYS A 1 428 ? 155.644 144.576 117.014 1.00 44.71  ? 421 LYS A N   1 
ATOM   3005  C  CA  . LYS A 1 428 ? 154.865 145.285 118.020 1.00 44.71  ? 421 LYS A CA  1 
ATOM   3006  C  C   . LYS A 1 428 ? 155.677 146.454 118.562 1.00 44.71  ? 421 LYS A C   1 
ATOM   3007  O  O   . LYS A 1 428 ? 156.861 146.300 118.877 1.00 44.71  ? 421 LYS A O   1 
ATOM   3008  C  CB  . LYS A 1 428 ? 154.453 144.348 119.155 1.00 44.71  ? 421 LYS A CB  1 
ATOM   3009  C  CG  . LYS A 1 428 ? 153.429 144.950 120.100 1.00 44.71  ? 421 LYS A CG  1 
ATOM   3010  C  CD  . LYS A 1 428 ? 152.839 143.902 121.025 1.00 44.71  ? 421 LYS A CD  1 
ATOM   3011  C  CE  . LYS A 1 428 ? 151.864 144.529 122.007 1.00 44.71  ? 421 LYS A CE  1 
ATOM   3012  N  NZ  . LYS A 1 428 ? 150.816 145.328 121.314 1.00 44.71  ? 421 LYS A NZ  1 
ATOM   3013  N  N   . GLU A 1 429 ? 155.036 147.615 118.676 1.00 42.98  ? 422 GLU A N   1 
ATOM   3014  C  CA  . GLU A 1 429 ? 155.710 148.858 119.027 1.00 42.98  ? 422 GLU A CA  1 
ATOM   3015  C  C   . GLU A 1 429 ? 155.494 149.207 120.493 1.00 42.98  ? 422 GLU A C   1 
ATOM   3016  O  O   . GLU A 1 429 ? 154.390 149.055 121.023 1.00 42.98  ? 422 GLU A O   1 
ATOM   3017  C  CB  . GLU A 1 429 ? 155.204 150.010 118.158 1.00 42.98  ? 422 GLU A CB  1 
ATOM   3018  C  CG  . GLU A 1 429 ? 155.922 150.166 116.835 1.00 42.98  ? 422 GLU A CG  1 
ATOM   3019  C  CD  . GLU A 1 429 ? 155.781 151.562 116.265 1.00 42.98  ? 422 GLU A CD  1 
ATOM   3020  O  OE1 . GLU A 1 429 ? 154.989 152.354 116.818 1.00 42.98  ? 422 GLU A OE1 1 
ATOM   3021  O  OE2 . GLU A 1 429 ? 156.462 151.869 115.264 1.00 42.98  ? 422 GLU A OE2 1 
ATOM   3022  N  N   . TYR A 1 430 ? 156.556 149.679 121.143 1.00 37.19  ? 423 TYR A N   1 
ATOM   3023  C  CA  . TYR A 1 430 ? 156.474 150.292 122.468 1.00 37.19  ? 423 TYR A CA  1 
ATOM   3024  C  C   . TYR A 1 430 ? 157.131 151.662 122.403 1.00 37.19  ? 423 TYR A C   1 
ATOM   3025  O  O   . TYR A 1 430 ? 158.360 151.774 122.566 1.00 37.19  ? 423 TYR A O   1 
ATOM   3026  C  CB  . TYR A 1 430 ? 157.140 149.425 123.534 1.00 37.19  ? 423 TYR A CB  1 
ATOM   3027  C  CG  . TYR A 1 430 ? 156.575 148.028 123.641 1.00 37.19  ? 423 TYR A CG  1 
ATOM   3028  C  CD1 . TYR A 1 430 ? 157.050 147.002 122.842 1.00 37.19  ? 423 TYR A CD1 1 
ATOM   3029  C  CD2 . TYR A 1 430 ? 155.563 147.739 124.544 1.00 37.19  ? 423 TYR A CD2 1 
ATOM   3030  C  CE1 . TYR A 1 430 ? 156.536 145.730 122.941 1.00 37.19  ? 423 TYR A CE1 1 
ATOM   3031  C  CE2 . TYR A 1 430 ? 155.043 146.468 124.649 1.00 37.19  ? 423 TYR A CE2 1 
ATOM   3032  C  CZ  . TYR A 1 430 ? 155.534 145.467 123.844 1.00 37.19  ? 423 TYR A CZ  1 
ATOM   3033  O  OH  . TYR A 1 430 ? 155.021 144.196 123.940 1.00 37.19  ? 423 TYR A OH  1 
ATOM   3034  N  N   . PRO A 1 431 ? 156.369 152.725 122.128 1.00 34.35  ? 424 PRO A N   1 
ATOM   3035  C  CA  . PRO A 1 431 ? 156.959 154.071 122.082 1.00 34.35  ? 424 PRO A CA  1 
ATOM   3036  C  C   . PRO A 1 431 ? 157.315 154.642 123.442 1.00 34.35  ? 424 PRO A C   1 
ATOM   3037  O  O   . PRO A 1 431 ? 157.938 155.709 123.492 1.00 34.35  ? 424 PRO A O   1 
ATOM   3038  C  CB  . PRO A 1 431 ? 155.866 154.913 121.409 1.00 34.35  ? 424 PRO A CB  1 
ATOM   3039  C  CG  . PRO A 1 431 ? 154.954 153.928 120.756 1.00 34.35  ? 424 PRO A CG  1 
ATOM   3040  C  CD  . PRO A 1 431 ? 154.993 152.711 121.612 1.00 34.35  ? 424 PRO A CD  1 
ATOM   3041  N  N   . LEU A 1 432 ? 156.924 153.999 124.542 1.00 28.66  ? 425 LEU A N   1 
ATOM   3042  C  CA  . LEU A 1 432 ? 157.280 154.467 125.875 1.00 28.66  ? 425 LEU A CA  1 
ATOM   3043  C  C   . LEU A 1 432 ? 158.206 153.505 126.607 1.00 28.66  ? 425 LEU A C   1 
ATOM   3044  O  O   . LEU A 1 432 ? 158.395 153.644 127.819 1.00 28.66  ? 425 LEU A O   1 
ATOM   3045  C  CB  . LEU A 1 432 ? 156.022 154.723 126.708 1.00 28.66  ? 425 LEU A CB  1 
ATOM   3046  C  CG  . LEU A 1 432 ? 155.038 155.768 126.180 1.00 28.66  ? 425 LEU A CG  1 
ATOM   3047  C  CD1 . LEU A 1 432 ? 153.617 155.265 126.290 1.00 28.66  ? 425 LEU A CD1 1 
ATOM   3048  C  CD2 . LEU A 1 432 ? 155.190 157.077 126.925 1.00 28.66  ? 425 LEU A CD2 1 
ATOM   3049  N  N   . GLY A 1 433 ? 158.783 152.533 125.908 1.00 31.39  ? 426 GLY A N   1 
ATOM   3050  C  CA  . GLY A 1 433 ? 159.757 151.647 126.511 1.00 31.39  ? 426 GLY A CA  1 
ATOM   3051  C  C   . GLY A 1 433 ? 159.126 150.557 127.354 1.00 31.39  ? 426 GLY A C   1 
ATOM   3052  O  O   . GLY A 1 433 ? 157.909 150.387 127.416 1.00 31.39  ? 426 GLY A O   1 
ATOM   3053  N  N   . ARG A 1 434 ? 159.994 149.796 128.019 1.00 31.17  ? 427 ARG A N   1 
ATOM   3054  C  CA  . ARG A 1 434 ? 159.582 148.697 128.881 1.00 31.17  ? 427 ARG A CA  1 
ATOM   3055  C  C   . ARG A 1 434 ? 160.281 148.823 130.225 1.00 31.17  ? 427 ARG A C   1 
ATOM   3056  O  O   . ARG A 1 434 ? 161.487 149.081 130.277 1.00 31.17  ? 427 ARG A O   1 
ATOM   3057  C  CB  . ARG A 1 434 ? 159.911 147.345 128.246 1.00 31.17  ? 427 ARG A CB  1 
ATOM   3058  C  CG  . ARG A 1 434 ? 159.421 147.183 126.822 1.00 31.17  ? 427 ARG A CG  1 
ATOM   3059  C  CD  . ARG A 1 434 ? 159.350 145.717 126.433 1.00 31.17  ? 427 ARG A CD  1 
ATOM   3060  N  NE  . ARG A 1 434 ? 158.260 145.027 127.112 1.00 31.17  ? 427 ARG A NE  1 
ATOM   3061  C  CZ  . ARG A 1 434 ? 157.925 143.763 126.897 1.00 31.17  ? 427 ARG A CZ  1 
ATOM   3062  N  NH1 . ARG A 1 434 ? 158.587 143.009 126.036 1.00 31.17  ? 427 ARG A NH1 1 
ATOM   3063  N  NH2 . ARG A 1 434 ? 156.899 143.242 127.563 1.00 31.17  ? 427 ARG A NH2 1 
ATOM   3064  N  N   . ILE A 1 435 ? 159.525 148.639 131.309 1.00 30.15  ? 428 ILE A N   1 
ATOM   3065  C  CA  . ILE A 1 435 ? 160.110 148.653 132.644 1.00 30.15  ? 428 ILE A CA  1 
ATOM   3066  C  C   . ILE A 1 435 ? 161.019 147.445 132.811 1.00 30.15  ? 428 ILE A C   1 
ATOM   3067  O  O   . ILE A 1 435 ? 160.692 146.334 132.374 1.00 30.15  ? 428 ILE A O   1 
ATOM   3068  C  CB  . ILE A 1 435 ? 159.007 148.659 133.715 1.00 30.15  ? 428 ILE A CB  1 
ATOM   3069  C  CG1 . ILE A 1 435 ? 158.065 149.842 133.521 1.00 30.15  ? 428 ILE A CG1 1 
ATOM   3070  C  CG2 . ILE A 1 435 ? 159.614 148.727 135.096 1.00 30.15  ? 428 ILE A CG2 1 
ATOM   3071  C  CD1 . ILE A 1 435 ? 158.756 151.167 133.534 1.00 30.15  ? 428 ILE A CD1 1 
ATOM   3072  N  N   . LEU A 1 436 ? 162.168 147.652 133.447 1.00 32.13  ? 429 LEU A N   1 
ATOM   3073  C  CA  . LEU A 1 436 ? 163.125 146.588 133.719 1.00 32.13  ? 429 LEU A CA  1 
ATOM   3074  C  C   . LEU A 1 436 ? 163.428 146.578 135.209 1.00 32.13  ? 429 LEU A C   1 
ATOM   3075  O  O   . LEU A 1 436 ? 163.894 147.585 135.756 1.00 32.13  ? 429 LEU A O   1 
ATOM   3076  C  CB  . LEU A 1 436 ? 164.413 146.788 132.917 1.00 32.13  ? 429 LEU A CB  1 
ATOM   3077  C  CG  . LEU A 1 436 ? 164.299 146.932 131.401 1.00 32.13  ? 429 LEU A CG  1 
ATOM   3078  C  CD1 . LEU A 1 436 ? 165.675 147.058 130.781 1.00 32.13  ? 429 LEU A CD1 1 
ATOM   3079  C  CD2 . LEU A 1 436 ? 163.562 145.755 130.811 1.00 32.13  ? 429 LEU A CD2 1 
ATOM   3080  N  N   . PHE A 1 437 ? 163.159 145.448 135.859 1.00 35.34  ? 430 PHE A N   1 
ATOM   3081  C  CA  . PHE A 1 437 ? 163.553 145.237 137.243 1.00 35.34  ? 430 PHE A CA  1 
ATOM   3082  C  C   . PHE A 1 437 ? 164.040 143.807 137.402 1.00 35.34  ? 430 PHE A C   1 
ATOM   3083  O  O   . PHE A 1 437 ? 163.565 142.896 136.720 1.00 35.34  ? 430 PHE A O   1 
ATOM   3084  C  CB  . PHE A 1 437 ? 162.410 145.536 138.229 1.00 35.34  ? 430 PHE A CB  1 
ATOM   3085  C  CG  . PHE A 1 437 ? 161.193 144.679 138.055 1.00 35.34  ? 430 PHE A CG  1 
ATOM   3086  C  CD1 . PHE A 1 437 ? 161.103 143.445 138.671 1.00 35.34  ? 430 PHE A CD1 1 
ATOM   3087  C  CD2 . PHE A 1 437 ? 160.119 145.129 137.314 1.00 35.34  ? 430 PHE A CD2 1 
ATOM   3088  C  CE1 . PHE A 1 437 ? 159.976 142.667 138.524 1.00 35.34  ? 430 PHE A CE1 1 
ATOM   3089  C  CE2 . PHE A 1 437 ? 158.991 144.354 137.165 1.00 35.34  ? 430 PHE A CE2 1 
ATOM   3090  C  CZ  . PHE A 1 437 ? 158.920 143.122 137.769 1.00 35.34  ? 430 PHE A CZ  1 
ATOM   3091  N  N   . GLY A 1 438 ? 164.991 143.618 138.311 1.00 38.11  ? 431 GLY A N   1 
ATOM   3092  C  CA  . GLY A 1 438 ? 165.661 142.343 138.486 1.00 38.11  ? 431 GLY A CA  1 
ATOM   3093  C  C   . GLY A 1 438 ? 165.178 141.611 139.723 1.00 38.11  ? 431 GLY A C   1 
ATOM   3094  O  O   . GLY A 1 438 ? 164.739 142.229 140.694 1.00 38.11  ? 431 GLY A O   1 
ATOM   3095  N  N   . ASP A 1 439 ? 165.265 140.286 139.678 1.00 43.88  ? 432 ASP A N   1 
ATOM   3096  C  CA  . ASP A 1 439 ? 164.919 139.426 140.804 1.00 43.88  ? 432 ASP A CA  1 
ATOM   3097  C  C   . ASP A 1 439 ? 165.537 138.049 140.561 1.00 43.88  ? 432 ASP A C   1 
ATOM   3098  O  O   . ASP A 1 439 ? 166.237 137.835 139.566 1.00 43.88  ? 432 ASP A O   1 
ATOM   3099  C  CB  . ASP A 1 439 ? 163.398 139.442 141.045 1.00 43.88  ? 432 ASP A CB  1 
ATOM   3100  C  CG  . ASP A 1 439 ? 162.614 138.415 140.220 1.00 43.88  ? 432 ASP A CG  1 
ATOM   3101  O  OD1 . ASP A 1 439 ? 161.369 138.460 140.305 1.00 43.88  ? 432 ASP A OD1 1 
ATOM   3102  O  OD2 . ASP A 1 439 ? 163.178 137.611 139.453 1.00 43.88  ? 432 ASP A OD2 1 
ATOM   3103  N  N   . SER A 1 440 ? 165.274 137.113 141.470 1.00 47.00  ? 433 SER A N   1 
ATOM   3104  C  CA  . SER A 1 440 ? 165.936 135.817 141.436 1.00 47.00  ? 433 SER A CA  1 
ATOM   3105  C  C   . SER A 1 440 ? 165.452 134.977 140.256 1.00 47.00  ? 433 SER A C   1 
ATOM   3106  O  O   . SER A 1 440 ? 164.361 135.178 139.716 1.00 47.00  ? 433 SER A O   1 
ATOM   3107  C  CB  . SER A 1 440 ? 165.697 135.061 142.742 1.00 47.00  ? 433 SER A CB  1 
ATOM   3108  O  OG  . SER A 1 440 ? 164.323 134.765 142.914 1.00 47.00  ? 433 SER A OG  1 
ATOM   3109  N  N   . CYS A 1 441 ? 166.291 134.016 139.860 1.00 46.19  ? 434 CYS A N   1 
ATOM   3110  C  CA  . CYS A 1 441 ? 165.963 133.166 138.719 1.00 46.19  ? 434 CYS A CA  1 
ATOM   3111  C  C   . CYS A 1 441 ? 164.763 132.275 139.017 1.00 46.19  ? 434 CYS A C   1 
ATOM   3112  O  O   . CYS A 1 441 ? 163.811 132.218 138.231 1.00 46.19  ? 434 CYS A O   1 
ATOM   3113  C  CB  . CYS A 1 441 ? 167.174 132.320 138.330 1.00 46.19  ? 434 CYS A CB  1 
ATOM   3114  S  SG  . CYS A 1 441 ? 166.795 130.977 137.187 1.00 46.19  ? 434 CYS A SG  1 
ATOM   3115  N  N   . TYR A 1 442 ? 164.791 131.572 140.144 1.00 47.47  ? 435 TYR A N   1 
ATOM   3116  C  CA  . TYR A 1 442 ? 163.692 130.717 140.562 1.00 47.47  ? 435 TYR A CA  1 
ATOM   3117  C  C   . TYR A 1 442 ? 163.461 130.896 142.053 1.00 47.47  ? 435 TYR A C   1 
ATOM   3118  O  O   . TYR A 1 442 ? 164.413 131.132 142.806 1.00 47.47  ? 435 TYR A O   1 
ATOM   3119  C  CB  . TYR A 1 442 ? 163.969 129.238 140.245 1.00 47.47  ? 435 TYR A CB  1 
ATOM   3120  C  CG  . TYR A 1 442 ? 165.047 128.597 141.092 1.00 47.47  ? 435 TYR A CG  1 
ATOM   3121  C  CD1 . TYR A 1 442 ? 164.734 127.944 142.274 1.00 47.47  ? 435 TYR A CD1 1 
ATOM   3122  C  CD2 . TYR A 1 442 ? 166.376 128.639 140.704 1.00 47.47  ? 435 TYR A CD2 1 
ATOM   3123  C  CE1 . TYR A 1 442 ? 165.712 127.359 143.047 1.00 47.47  ? 435 TYR A CE1 1 
ATOM   3124  C  CE2 . TYR A 1 442 ? 167.362 128.055 141.471 1.00 47.47  ? 435 TYR A CE2 1 
ATOM   3125  C  CZ  . TYR A 1 442 ? 167.023 127.417 142.642 1.00 47.47  ? 435 TYR A CZ  1 
ATOM   3126  O  OH  . TYR A 1 442 ? 167.999 126.831 143.412 1.00 47.47  ? 435 TYR A OH  1 
ATOM   3127  N  N   . PRO A 1 443 ? 162.214 130.796 142.507 1.00 51.47  ? 436 PRO A N   1 
ATOM   3128  C  CA  . PRO A 1 443 ? 161.942 130.942 143.941 1.00 51.47  ? 436 PRO A CA  1 
ATOM   3129  C  C   . PRO A 1 443 ? 162.586 129.827 144.747 1.00 51.47  ? 436 PRO A C   1 
ATOM   3130  O  O   . PRO A 1 443 ? 162.570 128.660 144.351 1.00 51.47  ? 436 PRO A O   1 
ATOM   3131  C  CB  . PRO A 1 443 ? 160.414 130.879 144.019 1.00 51.47  ? 436 PRO A CB  1 
ATOM   3132  C  CG  . PRO A 1 443 ? 159.996 130.172 142.786 1.00 51.47  ? 436 PRO A CG  1 
ATOM   3133  C  CD  . PRO A 1 443 ? 160.988 130.545 141.733 1.00 51.47  ? 436 PRO A CD  1 
ATOM   3134  N  N   . SER A 1 444 ? 163.147 130.195 145.892 1.00 58.07  ? 437 SER A N   1 
ATOM   3135  C  CA  . SER A 1 444 ? 163.814 129.235 146.761 1.00 58.07  ? 437 SER A CA  1 
ATOM   3136  C  C   . SER A 1 444 ? 163.709 129.740 148.196 1.00 58.07  ? 437 SER A C   1 
ATOM   3137  O  O   . SER A 1 444 ? 162.865 130.585 148.511 1.00 58.07  ? 437 SER A O   1 
ATOM   3138  C  CB  . SER A 1 444 ? 165.268 129.012 146.310 1.00 58.07  ? 437 SER A CB  1 
ATOM   3139  O  OG  . SER A 1 444 ? 166.041 130.185 146.476 1.00 58.07  ? 437 SER A OG  1 
ATOM   3140  N  N   . ASN A 1 445 ? 164.558 129.209 149.073 1.00 65.89  ? 438 ASN A N   1 
ATOM   3141  C  CA  . ASN A 1 445 ? 164.543 129.575 150.484 1.00 65.89  ? 438 ASN A CA  1 
ATOM   3142  C  C   . ASN A 1 445 ? 165.458 130.748 150.836 1.00 65.89  ? 438 ASN A C   1 
ATOM   3143  O  O   . ASN A 1 445 ? 165.169 131.473 151.795 1.00 65.89  ? 438 ASN A O   1 
ATOM   3144  C  CB  . ASN A 1 445 ? 164.809 128.309 151.327 1.00 65.89  ? 438 ASN A CB  1 
ATOM   3145  C  CG  . ASN A 1 445 ? 166.292 128.041 151.630 1.00 65.89  ? 438 ASN A CG  1 
ATOM   3146  O  OD1 . ASN A 1 445 ? 167.185 128.827 151.329 1.00 65.89  ? 438 ASN A OD1 1 
ATOM   3147  N  ND2 . ASN A 1 445 ? 166.543 126.895 152.250 1.00 65.89  ? 438 ASN A ND2 1 
ATOM   3148  N  N   . ASP A 1 446 ? 166.551 130.954 150.104 1.00 65.92  ? 439 ASP A N   1 
ATOM   3149  C  CA  . ASP A 1 446 ? 167.401 132.129 150.278 1.00 65.92  ? 439 ASP A CA  1 
ATOM   3150  C  C   . ASP A 1 446 ? 167.303 133.120 149.125 1.00 65.92  ? 439 ASP A C   1 
ATOM   3151  O  O   . ASP A 1 446 ? 168.107 134.056 149.061 1.00 65.92  ? 439 ASP A O   1 
ATOM   3152  C  CB  . ASP A 1 446 ? 168.861 131.716 150.488 1.00 65.92  ? 439 ASP A CB  1 
ATOM   3153  C  CG  . ASP A 1 446 ? 169.147 131.269 151.910 1.00 65.92  ? 439 ASP A CG  1 
ATOM   3154  O  OD1 . ASP A 1 446 ? 170.304 131.429 152.355 1.00 65.92  ? 439 ASP A OD1 1 
ATOM   3155  O  OD2 . ASP A 1 446 ? 168.214 130.820 152.605 1.00 65.92  ? 439 ASP A OD2 1 
ATOM   3156  N  N   . SER A 1 447 ? 166.349 132.945 148.218 1.00 57.22  ? 440 SER A N   1 
ATOM   3157  C  CA  . SER A 1 447 ? 166.179 133.902 147.139 1.00 57.22  ? 440 SER A CA  1 
ATOM   3158  C  C   . SER A 1 447 ? 165.401 135.123 147.620 1.00 57.22  ? 440 SER A C   1 
ATOM   3159  O  O   . SER A 1 447 ? 164.630 135.064 148.581 1.00 57.22  ? 440 SER A O   1 
ATOM   3160  C  CB  . SER A 1 447 ? 165.457 133.264 145.955 1.00 57.22  ? 440 SER A CB  1 
ATOM   3161  O  OG  . SER A 1 447 ? 164.054 133.291 146.148 1.00 57.22  ? 440 SER A OG  1 
ATOM   3162  N  N   . ARG A 1 448 ? 165.612 136.239 146.930 1.00 52.52  ? 441 ARG A N   1 
ATOM   3163  C  CA  . ARG A 1 448 ? 164.908 137.482 147.198 1.00 52.52  ? 441 ARG A CA  1 
ATOM   3164  C  C   . ARG A 1 448 ? 164.075 137.865 145.984 1.00 52.52  ? 441 ARG A C   1 
ATOM   3165  O  O   . ARG A 1 448 ? 164.256 137.331 144.887 1.00 52.52  ? 441 ARG A O   1 
ATOM   3166  C  CB  . ARG A 1 448 ? 165.880 138.618 147.537 1.00 52.52  ? 441 ARG A CB  1 
ATOM   3167  C  CG  . ARG A 1 448 ? 166.729 138.370 148.765 1.00 52.52  ? 441 ARG A CG  1 
ATOM   3168  C  CD  . ARG A 1 448 ? 167.890 139.343 148.821 1.00 52.52  ? 441 ARG A CD  1 
ATOM   3169  N  NE  . ARG A 1 448 ? 168.828 139.132 147.727 1.00 52.52  ? 441 ARG A NE  1 
ATOM   3170  C  CZ  . ARG A 1 448 ? 169.860 139.922 147.466 1.00 52.52  ? 441 ARG A CZ  1 
ATOM   3171  N  NH1 . ARG A 1 448 ? 170.111 140.994 148.199 1.00 52.52  ? 441 ARG A NH1 1 
ATOM   3172  N  NH2 . ARG A 1 448 ? 170.661 139.627 146.447 1.00 52.52  ? 441 ARG A NH2 1 
ATOM   3173  N  N   . GLN A 1 449 ? 163.153 138.801 146.189 1.00 51.11  ? 442 GLN A N   1 
ATOM   3174  C  CA  . GLN A 1 449 ? 162.323 139.283 145.098 1.00 51.11  ? 442 GLN A CA  1 
ATOM   3175  C  C   . GLN A 1 449 ? 161.829 140.684 145.420 1.00 51.11  ? 442 GLN A C   1 
ATOM   3176  O  O   . GLN A 1 449 ? 161.739 141.081 146.584 1.00 51.11  ? 442 GLN A O   1 
ATOM   3177  C  CB  . GLN A 1 449 ? 161.139 138.345 144.837 1.00 51.11  ? 442 GLN A CB  1 
ATOM   3178  C  CG  . GLN A 1 449 ? 160.027 138.449 145.867 1.00 51.11  ? 442 GLN A CG  1 
ATOM   3179  C  CD  . GLN A 1 449 ? 158.700 137.932 145.348 1.00 51.11  ? 442 GLN A CD  1 
ATOM   3180  O  OE1 . GLN A 1 449 ? 158.558 137.628 144.164 1.00 51.11  ? 442 GLN A OE1 1 
ATOM   3181  N  NE2 . GLN A 1 449 ? 157.715 137.834 146.234 1.00 51.11  ? 442 GLN A NE2 1 
ATOM   3182  N  N   . MET A 1 450 ? 161.515 141.434 144.366 1.00 51.10  ? 443 MET A N   1 
ATOM   3183  C  CA  . MET A 1 450 ? 160.828 142.705 144.539 1.00 51.10  ? 443 MET A CA  1 
ATOM   3184  C  C   . MET A 1 450 ? 159.471 142.466 145.185 1.00 51.10  ? 443 MET A C   1 
ATOM   3185  O  O   . MET A 1 450 ? 158.835 141.430 144.977 1.00 51.10  ? 443 MET A O   1 
ATOM   3186  C  CB  . MET A 1 450 ? 160.651 143.411 143.194 1.00 51.10  ? 443 MET A CB  1 
ATOM   3187  C  CG  . MET A 1 450 ? 160.129 144.836 143.305 1.00 51.10  ? 443 MET A CG  1 
ATOM   3188  S  SD  . MET A 1 450 ? 160.517 145.874 141.885 1.00 51.10  ? 443 MET A SD  1 
ATOM   3189  C  CE  . MET A 1 450 ? 162.175 146.401 142.291 1.00 51.10  ? 443 MET A CE  1 
ATOM   3190  N  N   . HIS A 1 451 ? 159.033 143.429 145.991 1.00 49.02  ? 444 HIS A N   1 
ATOM   3191  C  CA  . HIS A 1 451 ? 157.781 143.260 146.711 1.00 49.02  ? 444 HIS A CA  1 
ATOM   3192  C  C   . HIS A 1 451 ? 156.614 143.101 145.745 1.00 49.02  ? 444 HIS A C   1 
ATOM   3193  O  O   . HIS A 1 451 ? 156.549 143.753 144.695 1.00 49.02  ? 444 HIS A O   1 
ATOM   3194  C  CB  . HIS A 1 451 ? 157.530 144.436 147.650 1.00 49.02  ? 444 HIS A CB  1 
ATOM   3195  C  CG  . HIS A 1 451 ? 156.551 144.128 148.737 1.00 49.02  ? 444 HIS A CG  1 
ATOM   3196  N  ND1 . HIS A 1 451 ? 155.190 144.277 148.576 1.00 49.02  ? 444 HIS A ND1 1 
ATOM   3197  C  CD2 . HIS A 1 451 ? 156.732 143.657 149.993 1.00 49.02  ? 444 HIS A CD2 1 
ATOM   3198  C  CE1 . HIS A 1 451 ? 154.576 143.922 149.690 1.00 49.02  ? 444 HIS A CE1 1 
ATOM   3199  N  NE2 . HIS A 1 451 ? 155.488 143.541 150.565 1.00 49.02  ? 444 HIS A NE2 1 
ATOM   3200  N  N   . GLN A 1 452 ? 155.688 142.217 146.114 1.00 46.53  ? 445 GLN A N   1 
ATOM   3201  C  CA  . GLN A 1 452 ? 154.575 141.901 145.232 1.00 46.53  ? 445 GLN A CA  1 
ATOM   3202  C  C   . GLN A 1 452 ? 153.700 143.116 144.975 1.00 46.53  ? 445 GLN A C   1 
ATOM   3203  O  O   . GLN A 1 452 ? 153.169 143.265 143.873 1.00 46.53  ? 445 GLN A O   1 
ATOM   3204  C  CB  . GLN A 1 452 ? 153.746 140.760 145.819 1.00 46.53  ? 445 GLN A CB  1 
ATOM   3205  C  CG  . GLN A 1 452 ? 152.981 139.969 144.777 1.00 46.53  ? 445 GLN A CG  1 
ATOM   3206  C  CD  . GLN A 1 452 ? 153.901 139.260 143.805 1.00 46.53  ? 445 GLN A CD  1 
ATOM   3207  O  OE1 . GLN A 1 452 ? 153.686 139.291 142.593 1.00 46.53  ? 445 GLN A OE1 1 
ATOM   3208  N  NE2 . GLN A 1 452 ? 154.940 138.625 144.331 1.00 46.53  ? 445 GLN A NE2 1 
ATOM   3209  N  N   . ALA A 1 453 ? 153.535 143.995 145.965 1.00 44.99  ? 446 ALA A N   1 
ATOM   3210  C  CA  . ALA A 1 453 ? 152.721 145.188 145.754 1.00 44.99  ? 446 ALA A CA  1 
ATOM   3211  C  C   . ALA A 1 453 ? 153.314 146.068 144.660 1.00 44.99  ? 446 ALA A C   1 
ATOM   3212  O  O   . ALA A 1 453 ? 152.599 146.533 143.763 1.00 44.99  ? 446 ALA A O   1 
ATOM   3213  C  CB  . ALA A 1 453 ? 152.581 145.966 147.061 1.00 44.99  ? 446 ALA A CB  1 
ATOM   3214  N  N   . LEU A 1 454 ? 154.630 146.291 144.707 1.00 42.27  ? 447 LEU A N   1 
ATOM   3215  C  CA  . LEU A 1 454 ? 155.285 147.076 143.667 1.00 42.27  ? 447 LEU A CA  1 
ATOM   3216  C  C   . LEU A 1 454 ? 155.194 146.385 142.313 1.00 42.27  ? 447 LEU A C   1 
ATOM   3217  O  O   . LEU A 1 454 ? 154.953 147.038 141.289 1.00 42.27  ? 447 LEU A O   1 
ATOM   3218  C  CB  . LEU A 1 454 ? 156.744 147.332 144.042 1.00 42.27  ? 447 LEU A CB  1 
ATOM   3219  C  CG  . LEU A 1 454 ? 156.981 148.026 145.383 1.00 42.27  ? 447 LEU A CG  1 
ATOM   3220  C  CD1 . LEU A 1 454 ? 158.452 148.359 145.571 1.00 42.27  ? 447 LEU A CD1 1 
ATOM   3221  C  CD2 . LEU A 1 454 ? 156.130 149.276 145.491 1.00 42.27  ? 447 LEU A CD2 1 
ATOM   3222  N  N   . GLN A 1 455 ? 155.385 145.062 142.285 1.00 40.86  ? 448 GLN A N   1 
ATOM   3223  C  CA  . GLN A 1 455 ? 155.313 144.348 141.012 1.00 40.86  ? 448 GLN A CA  1 
ATOM   3224  C  C   . GLN A 1 455 ? 153.920 144.439 140.400 1.00 40.86  ? 448 GLN A C   1 
ATOM   3225  O  O   . GLN A 1 455 ? 153.779 144.674 139.193 1.00 40.86  ? 448 GLN A O   1 
ATOM   3226  C  CB  . GLN A 1 455 ? 155.728 142.890 141.200 1.00 40.86  ? 448 GLN A CB  1 
ATOM   3227  C  CG  . GLN A 1 455 ? 157.164 142.611 140.793 1.00 40.86  ? 448 GLN A CG  1 
ATOM   3228  C  CD  . GLN A 1 455 ? 157.521 141.143 140.871 1.00 40.86  ? 448 GLN A CD  1 
ATOM   3229  O  OE1 . GLN A 1 455 ? 156.680 140.275 140.640 1.00 40.86  ? 448 GLN A OE1 1 
ATOM   3230  N  NE2 . GLN A 1 455 ? 158.775 140.856 141.197 1.00 40.86  ? 448 GLN A NE2 1 
ATOM   3231  N  N   . ASP A 1 456 ? 152.875 144.268 141.214 1.00 39.79  ? 449 ASP A N   1 
ATOM   3232  C  CA  . ASP A 1 456 ? 151.516 144.371 140.691 1.00 39.79  ? 449 ASP A CA  1 
ATOM   3233  C  C   . ASP A 1 456 ? 151.184 145.795 140.267 1.00 39.79  ? 449 ASP A C   1 
ATOM   3234  O  O   . ASP A 1 456 ? 150.473 145.992 139.279 1.00 39.79  ? 449 ASP A O   1 
ATOM   3235  C  CB  . ASP A 1 456 ? 150.486 143.865 141.704 1.00 39.79  ? 449 ASP A CB  1 
ATOM   3236  C  CG  . ASP A 1 456 ? 150.775 142.458 142.194 1.00 39.79  ? 449 ASP A CG  1 
ATOM   3237  O  OD1 . ASP A 1 456 ? 150.870 141.544 141.350 1.00 39.79  ? 449 ASP A OD1 1 
ATOM   3238  O  OD2 . ASP A 1 456 ? 150.833 142.249 143.423 1.00 39.79  ? 449 ASP A OD2 1 
ATOM   3239  N  N   . PHE A 1 457 ? 151.674 146.802 140.993 1.00 33.61  ? 450 PHE A N   1 
ATOM   3240  C  CA  . PHE A 1 457 ? 151.445 148.179 140.562 1.00 33.61  ? 450 PHE A CA  1 
ATOM   3241  C  C   . PHE A 1 457 ? 152.076 148.434 139.198 1.00 33.61  ? 450 PHE A C   1 
ATOM   3242  O  O   . PHE A 1 457 ? 151.433 148.977 138.288 1.00 33.61  ? 450 PHE A O   1 
ATOM   3243  C  CB  . PHE A 1 457 ? 151.995 149.154 141.603 1.00 33.61  ? 450 PHE A CB  1 
ATOM   3244  C  CG  . PHE A 1 457 ? 151.864 150.597 141.212 1.00 33.61  ? 450 PHE A CG  1 
ATOM   3245  C  CD1 . PHE A 1 457 ? 150.623 151.204 141.160 1.00 33.61  ? 450 PHE A CD1 1 
ATOM   3246  C  CD2 . PHE A 1 457 ? 152.980 151.349 140.900 1.00 33.61  ? 450 PHE A CD2 1 
ATOM   3247  C  CE1 . PHE A 1 457 ? 150.500 152.529 140.802 1.00 33.61  ? 450 PHE A CE1 1 
ATOM   3248  C  CE2 . PHE A 1 457 ? 152.859 152.674 140.541 1.00 33.61  ? 450 PHE A CE2 1 
ATOM   3249  C  CZ  . PHE A 1 457 ? 151.619 153.264 140.494 1.00 33.61  ? 450 PHE A CZ  1 
ATOM   3250  N  N   . LEU A 1 458 ? 153.334 148.018 139.031 1.00 35.22  ? 451 LEU A N   1 
ATOM   3251  C  CA  . LEU A 1 458 ? 154.015 148.218 137.757 1.00 35.22  ? 451 LEU A CA  1 
ATOM   3252  C  C   . LEU A 1 458 ? 153.310 147.474 136.631 1.00 35.22  ? 451 LEU A C   1 
ATOM   3253  O  O   . LEU A 1 458 ? 153.183 147.996 135.518 1.00 35.22  ? 451 LEU A O   1 
ATOM   3254  C  CB  . LEU A 1 458 ? 155.469 147.773 137.866 1.00 35.22  ? 451 LEU A CB  1 
ATOM   3255  C  CG  . LEU A 1 458 ? 156.332 148.605 138.810 1.00 35.22  ? 451 LEU A CG  1 
ATOM   3256  C  CD1 . LEU A 1 458 ? 157.764 148.120 138.767 1.00 35.22  ? 451 LEU A CD1 1 
ATOM   3257  C  CD2 . LEU A 1 458 ? 156.249 150.076 138.447 1.00 35.22  ? 451 LEU A CD2 1 
ATOM   3258  N  N   . SER A 1 459 ? 152.851 146.249 136.896 1.00 34.40  ? 452 SER A N   1 
ATOM   3259  C  CA  . SER A 1 459 ? 152.102 145.518 135.881 1.00 34.40  ? 452 SER A CA  1 
ATOM   3260  C  C   . SER A 1 459 ? 150.782 146.204 135.552 1.00 34.40  ? 452 SER A C   1 
ATOM   3261  O  O   . SER A 1 459 ? 150.380 146.238 134.385 1.00 34.40  ? 452 SER A O   1 
ATOM   3262  C  CB  . SER A 1 459 ? 151.857 144.082 136.340 1.00 34.40  ? 452 SER A CB  1 
ATOM   3263  O  OG  . SER A 1 459 ? 152.928 143.237 135.959 1.00 34.40  ? 452 SER A OG  1 
ATOM   3264  N  N   . ALA A 1 460 ? 150.096 146.751 136.560 1.00 31.96  ? 453 ALA A N   1 
ATOM   3265  C  CA  . ALA A 1 460 ? 148.828 147.431 136.323 1.00 31.96  ? 453 ALA A CA  1 
ATOM   3266  C  C   . ALA A 1 460 ? 149.012 148.677 135.472 1.00 31.96  ? 453 ALA A C   1 
ATOM   3267  O  O   . ALA A 1 460 ? 148.125 149.022 134.684 1.00 31.96  ? 453 ALA A O   1 
ATOM   3268  C  CB  . ALA A 1 460 ? 148.163 147.788 137.649 1.00 31.96  ? 453 ALA A CB  1 
ATOM   3269  N  N   . GLN A 1 461 ? 150.140 149.368 135.616 1.00 31.77  ? 454 GLN A N   1 
ATOM   3270  C  CA  . GLN A 1 461 ? 150.499 150.397 134.641 1.00 31.77  ? 454 GLN A CA  1 
ATOM   3271  C  C   . GLN A 1 461 ? 150.857 149.691 133.340 1.00 31.77  ? 454 GLN A C   1 
ATOM   3272  O  O   . GLN A 1 461 ? 151.974 149.198 133.174 1.00 31.77  ? 454 GLN A O   1 
ATOM   3273  C  CB  . GLN A 1 461 ? 151.656 151.249 135.146 1.00 31.77  ? 454 GLN A CB  1 
ATOM   3274  C  CG  . GLN A 1 461 ? 151.528 151.650 136.594 1.00 31.77  ? 454 GLN A CG  1 
ATOM   3275  C  CD  . GLN A 1 461 ? 150.288 152.470 136.853 1.00 31.77  ? 454 GLN A CD  1 
ATOM   3276  O  OE1 . GLN A 1 461 ? 150.169 153.598 136.381 1.00 31.77  ? 454 GLN A OE1 1 
ATOM   3277  N  NE2 . GLN A 1 461 ? 149.351 151.907 137.602 1.00 31.77  ? 454 GLN A NE2 1 
ATOM   3278  N  N   . GLN A 1 462 ? 149.904 149.634 132.408 1.00 30.04  ? 455 GLN A N   1 
ATOM   3279  C  CA  . GLN A 1 462 ? 150.083 148.793 131.228 1.00 30.04  ? 455 GLN A CA  1 
ATOM   3280  C  C   . GLN A 1 462 ? 151.097 149.386 130.259 1.00 30.04  ? 455 GLN A C   1 
ATOM   3281  O  O   . GLN A 1 462 ? 151.946 148.661 129.722 1.00 30.04  ? 455 GLN A O   1 
ATOM   3282  C  CB  . GLN A 1 462 ? 148.739 148.576 130.534 1.00 30.04  ? 455 GLN A CB  1 
ATOM   3283  C  CG  . GLN A 1 462 ? 147.570 148.428 131.493 1.00 30.04  ? 455 GLN A CG  1 
ATOM   3284  C  CD  . GLN A 1 462 ? 146.255 148.178 130.784 1.00 30.04  ? 455 GLN A CD  1 
ATOM   3285  O  OE1 . GLN A 1 462 ? 146.152 147.290 129.939 1.00 30.04  ? 455 GLN A OE1 1 
ATOM   3286  N  NE2 . GLN A 1 462 ? 145.239 148.959 131.129 1.00 30.04  ? 455 GLN A NE2 1 
ATOM   3287  N  N   . VAL A 1 463 ? 151.050 150.706 130.062 1.00 27.67  ? 456 VAL A N   1 
ATOM   3288  C  CA  . VAL A 1 463 ? 151.764 151.408 128.998 1.00 27.67  ? 456 VAL A CA  1 
ATOM   3289  C  C   . VAL A 1 463 ? 153.230 151.002 128.921 1.00 27.67  ? 456 VAL A C   1 
ATOM   3290  O  O   . VAL A 1 463 ? 153.859 151.110 127.864 1.00 27.67  ? 456 VAL A O   1 
ATOM   3291  C  CB  . VAL A 1 463 ? 151.637 152.930 129.178 1.00 27.67  ? 456 VAL A CB  1 
ATOM   3292  C  CG1 . VAL A 1 463 ? 150.213 153.369 128.907 1.00 27.67  ? 456 VAL A CG1 1 
ATOM   3293  C  CG2 . VAL A 1 463 ? 152.057 153.330 130.578 1.00 27.67  ? 456 VAL A CG2 1 
ATOM   3294  N  N   . GLN A 1 464 ? 153.790 150.531 130.029 1.00 29.10  ? 457 GLN A N   1 
ATOM   3295  C  CA  . GLN A 1 464 ? 155.135 149.964 130.032 1.00 29.10  ? 457 GLN A CA  1 
ATOM   3296  C  C   . GLN A 1 464 ? 155.040 148.604 130.716 1.00 29.10  ? 457 GLN A C   1 
ATOM   3297  O  O   . GLN A 1 464 ? 155.263 148.489 131.924 1.00 29.10  ? 457 GLN A O   1 
ATOM   3298  C  CB  . GLN A 1 464 ? 156.127 150.895 130.719 1.00 29.10  ? 457 GLN A CB  1 
ATOM   3299  C  CG  . GLN A 1 464 ? 156.112 152.312 130.175 1.00 29.10  ? 457 GLN A CG  1 
ATOM   3300  C  CD  . GLN A 1 464 ? 156.848 153.286 131.063 1.00 29.10  ? 457 GLN A CD  1 
ATOM   3301  O  OE1 . GLN A 1 464 ? 156.556 153.404 132.249 1.00 29.10  ? 457 GLN A OE1 1 
ATOM   3302  N  NE2 . GLN A 1 464 ? 157.806 154.000 130.488 1.00 29.10  ? 457 GLN A NE2 1 
ATOM   3303  N  N   . ALA A 1 465 ? 154.698 147.582 129.939 1.00 31.40  ? 458 ALA A N   1 
ATOM   3304  C  CA  . ALA A 1 465 ? 154.658 146.220 130.454 1.00 31.40  ? 458 ALA A CA  1 
ATOM   3305  C  C   . ALA A 1 465 ? 156.037 145.820 130.965 1.00 31.40  ? 458 ALA A C   1 
ATOM   3306  O  O   . ALA A 1 465 ? 157.011 145.872 130.201 1.00 31.40  ? 458 ALA A O   1 
ATOM   3307  C  CB  . ALA A 1 465 ? 154.197 145.252 129.368 1.00 31.40  ? 458 ALA A CB  1 
ATOM   3308  N  N   . PRO A 1 466 ? 156.166 145.415 132.224 1.00 32.20  ? 459 PRO A N   1 
ATOM   3309  C  CA  . PRO A 1 466 ? 157.495 145.190 132.799 1.00 32.20  ? 459 PRO A CA  1 
ATOM   3310  C  C   . PRO A 1 466 ? 158.155 143.927 132.269 1.00 32.20  ? 459 PRO A C   1 
ATOM   3311  O  O   . PRO A 1 466 ? 157.505 143.005 131.772 1.00 32.20  ? 459 PRO A O   1 
ATOM   3312  C  CB  . PRO A 1 466 ? 157.215 145.074 134.302 1.00 32.20  ? 459 PRO A CB  1 
ATOM   3313  C  CG  . PRO A 1 466 ? 155.849 145.661 134.493 1.00 32.20  ? 459 PRO A CG  1 
ATOM   3314  C  CD  . PRO A 1 466 ? 155.111 145.322 133.242 1.00 32.20  ? 459 PRO A CD  1 
ATOM   3315  N  N   . VAL A 1 467 ? 159.480 143.902 132.393 1.00 31.38  ? 460 VAL A N   1 
ATOM   3316  C  CA  . VAL A 1 467 ? 160.307 142.766 132.004 1.00 31.38  ? 460 VAL A CA  1 
ATOM   3317  C  C   . VAL A 1 467 ? 161.234 142.439 133.166 1.00 31.38  ? 460 VAL A C   1 
ATOM   3318  O  O   . VAL A 1 467 ? 161.903 143.331 133.698 1.00 31.38  ? 460 VAL A O   1 
ATOM   3319  C  CB  . VAL A 1 467 ? 161.120 143.065 130.730 1.00 31.38  ? 460 VAL A CB  1 
ATOM   3320  C  CG1 . VAL A 1 467 ? 162.189 142.013 130.517 1.00 31.38  ? 460 VAL A CG1 1 
ATOM   3321  C  CG2 . VAL A 1 467 ? 160.203 143.151 129.525 1.00 31.38  ? 460 VAL A CG2 1 
ATOM   3322  N  N   . LYS A 1 468 ? 161.277 141.169 133.555 1.00 35.46  ? 461 LYS A N   1 
ATOM   3323  C  CA  . LYS A 1 468 ? 162.077 140.721 134.687 1.00 35.46  ? 461 LYS A CA  1 
ATOM   3324  C  C   . LYS A 1 468 ? 163.458 140.281 134.220 1.00 35.46  ? 461 LYS A C   1 
ATOM   3325  O  O   . LYS A 1 468 ? 163.610 139.739 133.123 1.00 35.46  ? 461 LYS A O   1 
ATOM   3326  C  CB  . LYS A 1 468 ? 161.385 139.570 135.418 1.00 35.46  ? 461 LYS A CB  1 
ATOM   3327  C  CG  . LYS A 1 468 ? 160.244 140.011 136.317 1.00 35.46  ? 461 LYS A CG  1 
ATOM   3328  C  CD  . LYS A 1 468 ? 159.238 138.894 136.564 1.00 35.46  ? 461 LYS A CD  1 
ATOM   3329  C  CE  . LYS A 1 468 ? 159.913 137.541 136.714 1.00 35.46  ? 461 LYS A CE  1 
ATOM   3330  N  NZ  . LYS A 1 468 ? 160.840 137.505 137.875 1.00 35.46  ? 461 LYS A NZ  1 
ATOM   3331  N  N   . LEU A 1 469 ? 164.462 140.516 135.058 1.00 32.69  ? 462 LEU A N   1 
ATOM   3332  C  CA  . LEU A 1 469 ? 165.836 140.136 134.768 1.00 32.69  ? 462 LEU A CA  1 
ATOM   3333  C  C   . LEU A 1 469 ? 166.445 139.409 135.961 1.00 32.69  ? 462 LEU A C   1 
ATOM   3334  O  O   . LEU A 1 469 ? 165.913 139.426 137.073 1.00 32.69  ? 462 LEU A O   1 
ATOM   3335  C  CB  . LEU A 1 469 ? 166.688 141.357 134.404 1.00 32.69  ? 462 LEU A CB  1 
ATOM   3336  C  CG  . LEU A 1 469 ? 166.265 142.174 133.187 1.00 32.69  ? 462 LEU A CG  1 
ATOM   3337  C  CD1 . LEU A 1 469 ? 167.200 143.353 133.000 1.00 32.69  ? 462 LEU A CD1 1 
ATOM   3338  C  CD2 . LEU A 1 469 ? 166.251 141.303 131.951 1.00 32.69  ? 462 LEU A CD2 1 
ATOM   3339  N  N   . TYR A 1 470 ? 167.585 138.771 135.711 1.00 40.65  ? 463 TYR A N   1 
ATOM   3340  C  CA  . TYR A 1 470 ? 168.280 137.955 136.704 1.00 40.65  ? 463 TYR A CA  1 
ATOM   3341  C  C   . TYR A 1 470 ? 169.415 138.780 137.299 1.00 40.65  ? 463 TYR A C   1 
ATOM   3342  O  O   . TYR A 1 470 ? 170.531 138.787 136.776 1.00 40.65  ? 463 TYR A O   1 
ATOM   3343  C  CB  . TYR A 1 470 ? 168.796 136.670 136.065 1.00 40.65  ? 463 TYR A CB  1 
ATOM   3344  C  CG  . TYR A 1 470 ? 169.646 135.813 136.974 1.00 40.65  ? 463 TYR A CG  1 
ATOM   3345  C  CD1 . TYR A 1 470 ? 169.273 135.576 138.286 1.00 40.65  ? 463 TYR A CD1 1 
ATOM   3346  C  CD2 . TYR A 1 470 ? 170.821 135.239 136.514 1.00 40.65  ? 463 TYR A CD2 1 
ATOM   3347  C  CE1 . TYR A 1 470 ? 170.048 134.794 139.116 1.00 40.65  ? 463 TYR A CE1 1 
ATOM   3348  C  CE2 . TYR A 1 470 ? 171.602 134.456 137.336 1.00 40.65  ? 463 TYR A CE2 1 
ATOM   3349  C  CZ  . TYR A 1 470 ? 171.211 134.237 138.636 1.00 40.65  ? 463 TYR A CZ  1 
ATOM   3350  O  OH  . TYR A 1 470 ? 171.986 133.455 139.461 1.00 40.65  ? 463 TYR A OH  1 
ATOM   3351  N  N   . SER A 1 471 ? 169.127 139.475 138.402 1.00 43.69  ? 464 SER A N   1 
ATOM   3352  C  CA  . SER A 1 471 ? 170.126 140.292 139.081 1.00 43.69  ? 464 SER A CA  1 
ATOM   3353  C  C   . SER A 1 471 ? 170.195 139.992 140.574 1.00 43.69  ? 464 SER A C   1 
ATOM   3354  O  O   . SER A 1 471 ? 170.571 140.867 141.358 1.00 43.69  ? 464 SER A O   1 
ATOM   3355  C  CB  . SER A 1 471 ? 169.850 141.779 138.862 1.00 43.69  ? 464 SER A CB  1 
ATOM   3356  O  OG  . SER A 1 471 ? 168.616 142.154 139.446 1.00 43.69  ? 464 SER A OG  1 
ATOM   3357  N  N   . ASP A 1 472 ? 169.833 138.777 140.985 1.00 46.84  ? 465 ASP A N   1 
ATOM   3358  C  CA  . ASP A 1 472 ? 169.944 138.415 142.392 1.00 46.84  ? 465 ASP A CA  1 
ATOM   3359  C  C   . ASP A 1 472 ? 171.387 138.123 142.784 1.00 46.84  ? 465 ASP A C   1 
ATOM   3360  O  O   . ASP A 1 472 ? 171.747 138.250 143.960 1.00 46.84  ? 465 ASP A O   1 
ATOM   3361  C  CB  . ASP A 1 472 ? 169.054 137.211 142.693 1.00 46.84  ? 465 ASP A CB  1 
ATOM   3362  C  CG  . ASP A 1 472 ? 169.430 136.517 143.983 1.00 46.84  ? 465 ASP A CG  1 
ATOM   3363  O  OD1 . ASP A 1 472 ? 169.240 137.119 145.059 1.00 46.84  ? 465 ASP A OD1 1 
ATOM   3364  O  OD2 . ASP A 1 472 ? 169.925 135.373 143.922 1.00 46.84  ? 465 ASP A OD2 1 
ATOM   3365  N  N   . TRP A 1 473 ? 172.226 137.748 141.817 1.00 46.69  ? 466 TRP A N   1 
ATOM   3366  C  CA  . TRP A 1 473 ? 173.599 137.359 142.118 1.00 46.69  ? 466 TRP A CA  1 
ATOM   3367  C  C   . TRP A 1 473 ? 174.417 138.495 142.718 1.00 46.69  ? 466 TRP A C   1 
ATOM   3368  O  O   . TRP A 1 473 ? 175.368 138.229 143.461 1.00 46.69  ? 466 TRP A O   1 
ATOM   3369  C  CB  . TRP A 1 473 ? 174.282 136.832 140.856 1.00 46.69  ? 466 TRP A CB  1 
ATOM   3370  C  CG  . TRP A 1 473 ? 174.107 137.711 139.654 1.00 46.69  ? 466 TRP A CG  1 
ATOM   3371  C  CD1 . TRP A 1 473 ? 172.985 137.845 138.892 1.00 46.69  ? 466 TRP A CD1 1 
ATOM   3372  C  CD2 . TRP A 1 473 ? 175.091 138.571 139.071 1.00 46.69  ? 466 TRP A CD2 1 
ATOM   3373  N  NE1 . TRP A 1 473 ? 173.207 138.739 137.875 1.00 46.69  ? 466 TRP A NE1 1 
ATOM   3374  C  CE2 . TRP A 1 473 ? 174.494 139.198 137.963 1.00 46.69  ? 466 TRP A CE2 1 
ATOM   3375  C  CE3 . TRP A 1 473 ? 176.417 138.873 139.381 1.00 46.69  ? 466 TRP A CE3 1 
ATOM   3376  C  CZ2 . TRP A 1 473 ? 175.176 140.109 137.167 1.00 46.69  ? 466 TRP A CZ2 1 
ATOM   3377  C  CZ3 . TRP A 1 473 ? 177.092 139.776 138.590 1.00 46.69  ? 466 TRP A CZ3 1 
ATOM   3378  C  CH2 . TRP A 1 473 ? 176.472 140.384 137.495 1.00 46.69  ? 466 TRP A CH2 1 
ATOM   3379  N  N   . LEU A 1 474 ? 174.080 139.745 142.417 1.00 48.38  ? 467 LEU A N   1 
ATOM   3380  C  CA  . LEU A 1 474 ? 174.809 140.870 142.985 1.00 48.38  ? 467 LEU A CA  1 
ATOM   3381  C  C   . LEU A 1 474 ? 174.549 140.975 144.483 1.00 48.38  ? 467 LEU A C   1 
ATOM   3382  O  O   . LEU A 1 474 ? 173.452 140.685 144.967 1.00 48.38  ? 467 LEU A O   1 
ATOM   3383  C  CB  . LEU A 1 474 ? 174.410 142.170 142.293 1.00 48.38  ? 467 LEU A CB  1 
ATOM   3384  C  CG  . LEU A 1 474 ? 174.889 142.342 140.852 1.00 48.38  ? 467 LEU A CG  1 
ATOM   3385  C  CD1 . LEU A 1 474 ? 174.090 143.421 140.147 1.00 48.38  ? 467 LEU A CD1 1 
ATOM   3386  C  CD2 . LEU A 1 474 ? 176.368 142.669 140.825 1.00 48.38  ? 467 LEU A CD2 1 
ATOM   3387  N  N   . SER A 1 475 ? 175.581 141.394 145.222 1.00 52.74  ? 468 SER A N   1 
ATOM   3388  C  CA  . SER A 1 475 ? 175.457 141.502 146.673 1.00 52.74  ? 468 SER A CA  1 
ATOM   3389  C  C   . SER A 1 475 ? 174.362 142.484 147.059 1.00 52.74  ? 468 SER A C   1 
ATOM   3390  O  O   . SER A 1 475 ? 173.520 142.183 147.913 1.00 52.74  ? 468 SER A O   1 
ATOM   3391  C  CB  . SER A 1 475 ? 176.791 141.924 147.286 1.00 52.74  ? 468 SER A CB  1 
ATOM   3392  O  OG  . SER A 1 475 ? 176.689 142.031 148.695 1.00 52.74  ? 468 SER A OG  1 
ATOM   3393  N  N   . VAL A 1 476 ? 174.354 143.658 146.440 1.00 48.40  ? 469 VAL A N   1 
ATOM   3394  C  CA  . VAL A 1 476 ? 173.254 144.595 146.625 1.00 48.40  ? 469 VAL A CA  1 
ATOM   3395  C  C   . VAL A 1 476 ? 172.061 144.211 145.760 1.00 48.40  ? 469 VAL A C   1 
ATOM   3396  O  O   . VAL A 1 476 ? 170.911 144.321 146.191 1.00 48.40  ? 469 VAL A O   1 
ATOM   3397  C  CB  . VAL A 1 476 ? 173.739 146.029 146.336 1.00 48.40  ? 469 VAL A CB  1 
ATOM   3398  C  CG1 . VAL A 1 476 ? 174.544 146.073 145.047 1.00 48.40  ? 469 VAL A CG1 1 
ATOM   3399  C  CG2 . VAL A 1 476 ? 172.568 146.988 146.278 1.00 48.40  ? 469 VAL A CG2 1 
ATOM   3400  N  N   . GLY A 1 477 ? 172.315 143.734 144.543 1.00 49.08  ? 470 GLY A N   1 
ATOM   3401  C  CA  . GLY A 1 477 ? 171.254 143.286 143.665 1.00 49.08  ? 470 GLY A CA  1 
ATOM   3402  C  C   . GLY A 1 477 ? 170.561 144.416 142.937 1.00 49.08  ? 470 GLY A C   1 
ATOM   3403  O  O   . GLY A 1 477 ? 169.356 144.611 143.107 1.00 49.08  ? 470 GLY A O   1 
ATOM   3404  N  N   . HIS A 1 478 ? 171.307 145.176 142.135 1.00 47.27  ? 471 HIS A N   1 
ATOM   3405  C  CA  . HIS A 1 478 ? 170.773 146.323 141.412 1.00 47.27  ? 471 HIS A CA  1 
ATOM   3406  C  C   . HIS A 1 478 ? 171.081 146.188 139.927 1.00 47.27  ? 471 HIS A C   1 
ATOM   3407  O  O   . HIS A 1 478 ? 172.250 146.097 139.539 1.00 47.27  ? 471 HIS A O   1 
ATOM   3408  C  CB  . HIS A 1 478 ? 171.348 147.630 141.958 1.00 47.27  ? 471 HIS A CB  1 
ATOM   3409  C  CG  . HIS A 1 478 ? 170.763 148.044 143.271 1.00 47.27  ? 471 HIS A CG  1 
ATOM   3410  N  ND1 . HIS A 1 478 ? 171.113 149.216 143.904 1.00 47.27  ? 471 HIS A ND1 1 
ATOM   3411  C  CD2 . HIS A 1 478 ? 169.856 147.439 144.074 1.00 47.27  ? 471 HIS A CD2 1 
ATOM   3412  C  CE1 . HIS A 1 478 ? 170.444 149.318 145.039 1.00 47.27  ? 471 HIS A CE1 1 
ATOM   3413  N  NE2 . HIS A 1 478 ? 169.675 148.253 145.166 1.00 47.27  ? 471 HIS A NE2 1 
ATOM   3414  N  N   . VAL A 1 479 ? 170.034 146.212 139.098 1.00 43.27  ? 472 VAL A N   1 
ATOM   3415  C  CA  . VAL A 1 479 ? 170.208 146.160 137.654 1.00 43.27  ? 472 VAL A CA  1 
ATOM   3416  C  C   . VAL A 1 479 ? 170.933 147.380 137.120 1.00 43.27  ? 472 VAL A C   1 
ATOM   3417  O  O   . VAL A 1 479 ? 171.435 147.349 135.994 1.00 43.27  ? 472 VAL A O   1 
ATOM   3418  C  CB  . VAL A 1 479 ? 168.851 146.010 136.932 1.00 43.27  ? 472 VAL A CB  1 
ATOM   3419  C  CG1 . VAL A 1 479 ? 169.035 146.080 135.430 1.00 43.27  ? 472 VAL A CG1 1 
ATOM   3420  C  CG2 . VAL A 1 479 ? 168.181 144.718 137.333 1.00 43.27  ? 472 VAL A CG2 1 
ATOM   3421  N  N   . ASP A 1 480 ? 171.000 148.459 137.897 1.00 47.61  ? 473 ASP A N   1 
ATOM   3422  C  CA  . ASP A 1 480 ? 171.792 149.609 137.490 1.00 47.61  ? 473 ASP A CA  1 
ATOM   3423  C  C   . ASP A 1 480 ? 173.287 149.329 137.536 1.00 47.61  ? 473 ASP A C   1 
ATOM   3424  O  O   . ASP A 1 480 ? 174.067 150.153 137.049 1.00 47.61  ? 473 ASP A O   1 
ATOM   3425  C  CB  . ASP A 1 480 ? 171.411 150.830 138.351 1.00 47.61  ? 473 ASP A CB  1 
ATOM   3426  C  CG  . ASP A 1 480 ? 172.082 150.849 139.732 1.00 47.61  ? 473 ASP A CG  1 
ATOM   3427  O  OD1 . ASP A 1 480 ? 171.360 151.070 140.727 1.00 47.61  ? 473 ASP A OD1 1 
ATOM   3428  O  OD2 . ASP A 1 480 ? 173.318 150.716 139.845 1.00 47.61  ? 473 ASP A OD2 1 
ATOM   3429  N  N   . GLU A 1 481 ? 173.681 148.171 138.072 1.00 49.37  ? 474 GLU A N   1 
ATOM   3430  C  CA  . GLU A 1 481 ? 175.133 147.890 138.244 1.00 49.37  ? 474 GLU A CA  1 
ATOM   3431  C  C   . GLU A 1 481 ? 175.708 147.154 137.029 1.00 49.37  ? 474 GLU A C   1 
ATOM   3432  O  O   . GLU A 1 481 ? 176.929 146.906 137.032 1.00 49.37  ? 474 GLU A O   1 
ATOM   3433  C  CB  . GLU A 1 481 ? 175.365 147.063 139.508 1.00 49.37  ? 474 GLU A CB  1 
ATOM   3434  C  CG  . GLU A 1 481 ? 174.930 147.773 140.774 1.00 49.37  ? 474 GLU A CG  1 
ATOM   3435  C  CD  . GLU A 1 481 ? 175.795 147.456 141.981 1.00 49.37  ? 474 GLU A CD  1 
ATOM   3436  O  OE1 . GLU A 1 481 ? 176.273 146.308 142.075 1.00 49.37  ? 474 GLU A OE1 1 
ATOM   3437  O  OE2 . GLU A 1 481 ? 175.989 148.357 142.819 1.00 49.37  ? 474 GLU A OE2 1 
ATOM   3438  N  N   . PHE A 1 482 ? 174.882 146.804 136.038 1.00 40.19  ? 475 PHE A N   1 
ATOM   3439  C  CA  . PHE A 1 482 ? 175.426 146.000 134.909 1.00 40.19  ? 475 PHE A CA  1 
ATOM   3440  C  C   . PHE A 1 482 ? 174.795 146.415 133.574 1.00 40.19  ? 475 PHE A C   1 
ATOM   3441  O  O   . PHE A 1 482 ? 175.297 145.960 132.528 1.00 40.19  ? 475 PHE A O   1 
ATOM   3442  C  CB  . PHE A 1 482 ? 175.266 144.501 135.186 1.00 40.19  ? 475 PHE A CB  1 
ATOM   3443  C  CG  . PHE A 1 482 ? 173.853 144.009 135.376 1.00 40.19  ? 475 PHE A CG  1 
ATOM   3444  C  CD1 . PHE A 1 482 ? 172.936 144.040 134.338 1.00 40.19  ? 475 PHE A CD1 1 
ATOM   3445  C  CD2 . PHE A 1 482 ? 173.443 143.504 136.598 1.00 40.19  ? 475 PHE A CD2 1 
ATOM   3446  C  CE1 . PHE A 1 482 ? 171.641 143.581 134.518 1.00 40.19  ? 475 PHE A CE1 1 
ATOM   3447  C  CE2 . PHE A 1 482 ? 172.148 143.045 136.778 1.00 40.19  ? 475 PHE A CE2 1 
ATOM   3448  C  CZ  . PHE A 1 482 ? 171.249 143.084 135.738 1.00 40.19  ? 475 PHE A CZ  1 
ATOM   3449  N  N   . LEU A 1 483 ? 173.733 147.227 133.583 1.00 40.17  ? 476 LEU A N   1 
ATOM   3450  C  CA  . LEU A 1 483 ? 173.212 147.717 132.273 1.00 40.17  ? 476 LEU A CA  1 
ATOM   3451  C  C   . LEU A 1 483 ? 173.069 149.244 132.292 1.00 40.17  ? 476 LEU A C   1 
ATOM   3452  O  O   . LEU A 1 483 ? 172.928 149.809 133.393 1.00 40.17  ? 476 LEU A O   1 
ATOM   3453  C  CB  . LEU A 1 483 ? 171.914 146.999 131.869 1.00 40.17  ? 476 LEU A CB  1 
ATOM   3454  C  CG  . LEU A 1 483 ? 170.597 147.395 132.536 1.00 40.17  ? 476 LEU A CG  1 
ATOM   3455  C  CD1 . LEU A 1 483 ? 170.079 148.727 132.013 1.00 40.17  ? 476 LEU A CD1 1 
ATOM   3456  C  CD2 . LEU A 1 483 ? 169.557 146.321 132.258 1.00 40.17  ? 476 LEU A CD2 1 
ATOM   3457  N  N   . SER A 1 484 ? 173.117 149.871 131.114 1.00 39.08  ? 477 SER A N   1 
ATOM   3458  C  CA  . SER A 1 484 ? 173.009 151.351 130.992 1.00 39.08  ? 477 SER A CA  1 
ATOM   3459  C  C   . SER A 1 484 ? 172.608 151.720 129.559 1.00 39.08  ? 477 SER A C   1 
ATOM   3460  O  O   . SER A 1 484 ? 173.037 151.011 128.628 1.00 39.08  ? 477 SER A O   1 
ATOM   3461  C  CB  . SER A 1 484 ? 174.296 152.028 131.386 1.00 39.08  ? 477 SER A CB  1 
ATOM   3462  O  OG  . SER A 1 484 ? 174.497 151.954 132.789 1.00 39.08  ? 477 SER A OG  1 
ATOM   3463  N  N   . PHE A 1 485 ? 171.822 152.789 129.392 1.00 35.70  ? 478 PHE A N   1 
ATOM   3464  C  CA  . PHE A 1 485 ? 171.409 153.214 128.064 1.00 35.70  ? 478 PHE A CA  1 
ATOM   3465  C  C   . PHE A 1 485 ? 172.044 154.554 127.721 1.00 35.70  ? 478 PHE A C   1 
ATOM   3466  O  O   . PHE A 1 485 ? 172.253 155.404 128.591 1.00 35.70  ? 478 PHE A O   1 
ATOM   3467  C  CB  . PHE A 1 485 ? 169.888 153.318 127.957 1.00 35.70  ? 478 PHE A CB  1 
ATOM   3468  C  CG  . PHE A 1 485 ? 169.190 151.996 128.007 1.00 35.70  ? 478 PHE A CG  1 
ATOM   3469  C  CD1 . PHE A 1 485 ? 168.793 151.453 129.212 1.00 35.70  ? 478 PHE A CD1 1 
ATOM   3470  C  CD2 . PHE A 1 485 ? 168.945 151.287 126.847 1.00 35.70  ? 478 PHE A CD2 1 
ATOM   3471  C  CE1 . PHE A 1 485 ? 168.150 150.233 129.256 1.00 35.70  ? 478 PHE A CE1 1 
ATOM   3472  C  CE2 . PHE A 1 485 ? 168.304 150.066 126.885 1.00 35.70  ? 478 PHE A CE2 1 
ATOM   3473  C  CZ  . PHE A 1 485 ? 167.907 149.538 128.091 1.00 35.70  ? 478 PHE A CZ  1 
ATOM   3474  N  N   . VAL A 1 486 ? 172.428 154.705 126.452 1.00 41.24  ? 479 VAL A N   1 
ATOM   3475  C  CA  . VAL A 1 486 ? 173.095 155.960 126.001 1.00 41.24  ? 479 VAL A CA  1 
ATOM   3476  C  C   . VAL A 1 486 ? 172.413 156.404 124.704 1.00 41.24  ? 479 VAL A C   1 
ATOM   3477  O  O   . VAL A 1 486 ? 172.132 155.530 123.859 1.00 41.24  ? 479 VAL A O   1 
ATOM   3478  C  CB  . VAL A 1 486 ? 174.609 155.744 125.810 1.00 41.24  ? 479 VAL A CB  1 
ATOM   3479  C  CG1 . VAL A 1 486 ? 175.319 155.401 127.111 1.00 41.24  ? 479 VAL A CG1 1 
ATOM   3480  C  CG2 . VAL A 1 486 ? 174.905 154.703 124.741 1.00 41.24  ? 479 VAL A CG2 1 
ATOM   3481  N  N   . PRO A 1 487 ? 172.135 157.710 124.503 1.00 42.63  ? 480 PRO A N   1 
ATOM   3482  C  CA  . PRO A 1 487 ? 171.534 158.178 123.249 1.00 42.63  ? 480 PRO A CA  1 
ATOM   3483  C  C   . PRO A 1 487 ? 172.531 158.131 122.102 1.00 42.63  ? 480 PRO A C   1 
ATOM   3484  O  O   . PRO A 1 487 ? 173.703 158.486 122.253 1.00 42.63  ? 480 PRO A O   1 
ATOM   3485  C  CB  . PRO A 1 487 ? 171.122 159.618 123.570 1.00 42.63  ? 480 PRO A CB  1 
ATOM   3486  C  CG  . PRO A 1 487 ? 172.062 160.045 124.631 1.00 42.63  ? 480 PRO A CG  1 
ATOM   3487  C  CD  . PRO A 1 487 ? 172.432 158.821 125.424 1.00 42.63  ? 480 PRO A CD  1 
ATOM   3488  N  N   . ALA A 1 488 ? 172.050 157.688 120.942 1.00 44.89  ? 481 ALA A N   1 
ATOM   3489  C  CA  . ALA A 1 488 ? 172.894 157.506 119.774 1.00 44.89  ? 481 ALA A CA  1 
ATOM   3490  C  C   . ALA A 1 488 ? 172.272 158.177 118.558 1.00 44.89  ? 481 ALA A C   1 
ATOM   3491  O  O   . ALA A 1 488 ? 171.062 158.059 118.332 1.00 44.89  ? 481 ALA A O   1 
ATOM   3492  C  CB  . ALA A 1 488 ? 173.113 156.016 119.487 1.00 44.89  ? 481 ALA A CB  1 
ATOM   3493  N  N   . PRO A 1 489 ? 173.068 158.907 117.773 1.00 50.44  ? 482 PRO A N   1 
ATOM   3494  C  CA  . PRO A 1 489 ? 172.513 159.545 116.566 1.00 50.44  ? 482 PRO A CA  1 
ATOM   3495  C  C   . PRO A 1 489 ? 171.921 158.570 115.561 1.00 50.44  ? 482 PRO A C   1 
ATOM   3496  O  O   . PRO A 1 489 ? 170.900 158.882 114.937 1.00 50.44  ? 482 PRO A O   1 
ATOM   3497  C  CB  . PRO A 1 489 ? 173.719 160.283 115.969 1.00 50.44  ? 482 PRO A CB  1 
ATOM   3498  C  CG  . PRO A 1 489 ? 174.726 160.391 117.056 1.00 50.44  ? 482 PRO A CG  1 
ATOM   3499  C  CD  . PRO A 1 489 ? 174.346 159.500 118.196 1.00 50.44  ? 482 PRO A CD  1 
ATOM   3500  N  N   . ASP A 1 490 ? 172.524 157.400 115.387 1.00 50.58  ? 483 ASP A N   1 
ATOM   3501  C  CA  . ASP A 1 490 ? 172.219 156.516 114.268 1.00 50.58  ? 483 ASP A CA  1 
ATOM   3502  C  C   . ASP A 1 490 ? 171.521 155.247 114.749 1.00 50.58  ? 483 ASP A C   1 
ATOM   3503  O  O   . ASP A 1 490 ? 171.348 155.017 115.948 1.00 50.58  ? 483 ASP A O   1 
ATOM   3504  C  CB  . ASP A 1 490 ? 173.496 156.170 113.498 1.00 50.58  ? 483 ASP A CB  1 
ATOM   3505  C  CG  . ASP A 1 490 ? 174.579 155.604 114.394 1.00 50.58  ? 483 ASP A CG  1 
ATOM   3506  O  OD1 . ASP A 1 490 ? 174.974 156.295 115.355 1.00 50.58  ? 483 ASP A OD1 1 
ATOM   3507  O  OD2 . ASP A 1 490 ? 175.035 154.471 114.137 1.00 50.58  ? 483 ASP A OD2 1 
ATOM   3508  N  N   . ARG A 1 491 ? 171.120 154.424 113.781 1.00 47.81  ? 484 ARG A N   1 
ATOM   3509  C  CA  . ARG A 1 491 ? 170.473 153.122 114.008 1.00 47.81  ? 484 ARG A CA  1 
ATOM   3510  C  C   . ARG A 1 491 ? 169.176 153.368 114.778 1.00 47.81  ? 484 ARG A C   1 
ATOM   3511  O  O   . ARG A 1 491 ? 168.441 154.309 114.441 1.00 47.81  ? 484 ARG A O   1 
ATOM   3512  C  CB  . ARG A 1 491 ? 171.462 152.172 114.670 1.00 47.81  ? 484 ARG A CB  1 
ATOM   3513  C  CG  . ARG A 1 491 ? 172.647 151.797 113.793 1.00 47.81  ? 484 ARG A CG  1 
ATOM   3514  C  CD  . ARG A 1 491 ? 173.553 150.791 114.489 1.00 47.81  ? 484 ARG A CD  1 
ATOM   3515  N  NE  . ARG A 1 491 ? 174.712 150.430 113.681 1.00 47.81  ? 484 ARG A NE  1 
ATOM   3516  C  CZ  . ARG A 1 491 ? 174.710 149.512 112.723 1.00 47.81  ? 484 ARG A CZ  1 
ATOM   3517  N  NH1 . ARG A 1 491 ? 173.624 148.815 112.433 1.00 47.81  ? 484 ARG A NH1 1 
ATOM   3518  N  NH2 . ARG A 1 491 ? 175.830 149.283 112.043 1.00 47.81  ? 484 ARG A NH2 1 
ATOM   3519  N  N   . LYS A 1 492 ? 168.857 152.573 115.800 1.00 41.83  ? 485 LYS A N   1 
ATOM   3520  C  CA  . LYS A 1 492 ? 167.596 152.722 116.514 1.00 41.83  ? 485 LYS A CA  1 
ATOM   3521  C  C   . LYS A 1 492 ? 167.527 153.999 117.338 1.00 41.83  ? 485 LYS A C   1 
ATOM   3522  O  O   . LYS A 1 492 ? 166.449 154.332 117.840 1.00 41.83  ? 485 LYS A O   1 
ATOM   3523  C  CB  . LYS A 1 492 ? 167.360 151.516 117.423 1.00 41.83  ? 485 LYS A CB  1 
ATOM   3524  C  CG  . LYS A 1 492 ? 167.268 150.194 116.687 1.00 41.83  ? 485 LYS A CG  1 
ATOM   3525  C  CD  . LYS A 1 492 ? 166.068 150.164 115.760 1.00 41.83  ? 485 LYS A CD  1 
ATOM   3526  C  CE  . LYS A 1 492 ? 165.936 148.814 115.080 1.00 41.83  ? 485 LYS A CE  1 
ATOM   3527  N  NZ  . LYS A 1 492 ? 164.777 148.780 114.152 1.00 41.83  ? 485 LYS A NZ  1 
ATOM   3528  N  N   . GLY A 1 493 ? 168.672 154.644 117.560 1.00 41.33  ? 486 GLY A N   1 
ATOM   3529  C  CA  . GLY A 1 493 ? 168.687 155.852 118.404 1.00 41.33  ? 486 GLY A CA  1 
ATOM   3530  C  C   . GLY A 1 493 ? 169.319 155.608 119.759 1.00 41.33  ? 486 GLY A C   1 
ATOM   3531  O  O   . GLY A 1 493 ? 169.705 156.599 120.403 1.00 41.33  ? 486 GLY A O   1 
ATOM   3532  N  N   . PHE A 1 494 ? 169.411 154.349 120.195 1.00 36.83  ? 487 PHE A N   1 
ATOM   3533  C  CA  . PHE A 1 494 ? 169.968 154.043 121.543 1.00 36.83  ? 487 PHE A CA  1 
ATOM   3534  C  C   . PHE A 1 494 ? 171.084 153.018 121.400 1.00 36.83  ? 487 PHE A C   1 
ATOM   3535  O  O   . PHE A 1 494 ? 171.338 152.580 120.263 1.00 36.83  ? 487 PHE A O   1 
ATOM   3536  C  CB  . PHE A 1 494 ? 168.878 153.594 122.520 1.00 36.83  ? 487 PHE A CB  1 
ATOM   3537  C  CG  . PHE A 1 494 ? 168.155 152.291 122.224 1.00 36.83  ? 487 PHE A CG  1 
ATOM   3538  C  CD1 . PHE A 1 494 ? 166.956 152.287 121.523 1.00 36.83  ? 487 PHE A CD1 1 
ATOM   3539  C  CD2 . PHE A 1 494 ? 168.656 151.080 122.681 1.00 36.83  ? 487 PHE A CD2 1 
ATOM   3540  C  CE1 . PHE A 1 494 ? 166.293 151.100 121.267 1.00 36.83  ? 487 PHE A CE1 1 
ATOM   3541  C  CE2 . PHE A 1 494 ? 167.988 149.897 122.421 1.00 36.83  ? 487 PHE A CE2 1 
ATOM   3542  C  CZ  . PHE A 1 494 ? 166.811 149.909 121.714 1.00 36.83  ? 487 PHE A CZ  1 
ATOM   3543  N  N   . ARG A 1 495 ? 171.761 152.704 122.505 1.00 30.00  ? 488 ARG A N   1 
ATOM   3544  C  CA  . ARG A 1 495 ? 172.842 151.686 122.507 1.00 30.00  ? 488 ARG A CA  1 
ATOM   3545  C  C   . ARG A 1 495 ? 172.943 151.169 123.948 1.00 30.00  ? 488 ARG A C   1 
ATOM   3546  O  O   . ARG A 1 495 ? 173.394 151.937 124.820 1.00 30.00  ? 488 ARG A O   1 
ATOM   3547  C  CB  . ARG A 1 495 ? 174.173 152.271 122.029 1.00 30.00  ? 488 ARG A CB  1 
ATOM   3548  C  CG  . ARG A 1 495 ? 174.175 152.698 120.570 1.00 30.00  ? 488 ARG A CG  1 
ATOM   3549  C  CD  . ARG A 1 495 ? 175.517 153.211 120.075 1.00 30.00  ? 488 ARG A CD  1 
ATOM   3550  N  NE  . ARG A 1 495 ? 175.462 153.630 118.677 1.00 30.00  ? 488 ARG A NE  1 
ATOM   3551  C  CZ  . ARG A 1 495 ? 175.574 152.805 117.647 1.00 30.00  ? 488 ARG A CZ  1 
ATOM   3552  N  NH1 . ARG A 1 495 ? 175.745 151.504 117.852 1.00 30.00  ? 488 ARG A NH1 1 
ATOM   3553  N  NH2 . ARG A 1 495 ? 175.512 153.274 116.408 1.00 30.00  ? 488 ARG A NH2 1 
ATOM   3554  N  N   . LEU A 1 496 ? 172.500 149.936 124.191 1.00 39.20  ? 489 LEU A N   1 
ATOM   3555  C  CA  . LEU A 1 496 ? 172.606 149.377 125.563 1.00 39.20  ? 489 LEU A CA  1 
ATOM   3556  C  C   . LEU A 1 496 ? 174.072 149.045 125.889 1.00 39.20  ? 489 LEU A C   1 
ATOM   3557  O  O   . LEU A 1 496 ? 174.729 148.428 125.033 1.00 39.20  ? 489 LEU A O   1 
ATOM   3558  C  CB  . LEU A 1 496 ? 171.690 148.158 125.663 1.00 39.20  ? 489 LEU A CB  1 
ATOM   3559  C  CG  . LEU A 1 496 ? 171.864 147.263 126.891 1.00 39.20  ? 489 LEU A CG  1 
ATOM   3560  C  CD1 . LEU A 1 496 ? 171.489 148.004 128.157 1.00 39.20  ? 489 LEU A CD1 1 
ATOM   3561  C  CD2 . LEU A 1 496 ? 171.007 146.023 126.731 1.00 39.20  ? 489 LEU A CD2 1 
ATOM   3562  N  N   . LEU A 1 497 ? 174.568 149.449 127.061 1.00 41.94  ? 490 LEU A N   1 
ATOM   3563  C  CA  . LEU A 1 497 ? 175.952 149.145 127.513 1.00 41.94  ? 490 LEU A CA  1 
ATOM   3564  C  C   . LEU A 1 497 ? 175.893 148.095 128.627 1.00 41.94  ? 490 LEU A C   1 
ATOM   3565  O  O   . LEU A 1 497 ? 175.145 148.315 129.599 1.00 41.94  ? 490 LEU A O   1 
ATOM   3566  C  CB  . LEU A 1 497 ? 176.619 150.437 127.996 1.00 41.94  ? 490 LEU A CB  1 
ATOM   3567  C  CG  . LEU A 1 497 ? 177.125 151.366 126.892 1.00 41.94  ? 490 LEU A CG  1 
ATOM   3568  C  CD1 . LEU A 1 497 ? 176.009 152.256 126.369 1.00 41.94  ? 490 LEU A CD1 1 
ATOM   3569  C  CD2 . LEU A 1 497 ? 178.291 152.207 127.384 1.00 41.94  ? 490 LEU A CD2 1 
ATOM   3570  N  N   . LEU A 1 498 ? 176.649 147.002 128.485 1.00 43.77  ? 491 LEU A N   1 
ATOM   3571  C  CA  . LEU A 1 498 ? 176.600 145.899 129.484 1.00 43.77  ? 491 LEU A CA  1 
ATOM   3572  C  C   . LEU A 1 498 ? 177.998 145.660 130.065 1.00 43.77  ? 491 LEU A C   1 
ATOM   3573  O  O   . LEU A 1 498 ? 178.981 145.816 129.315 1.00 43.77  ? 491 LEU A O   1 
ATOM   3574  C  CB  . LEU A 1 498 ? 176.075 144.636 128.794 1.00 43.77  ? 491 LEU A CB  1 
ATOM   3575  C  CG  . LEU A 1 498 ? 174.632 144.709 128.299 1.00 43.77  ? 491 LEU A CG  1 
ATOM   3576  C  CD1 . LEU A 1 498 ? 174.196 143.378 127.707 1.00 43.77  ? 491 LEU A CD1 1 
ATOM   3577  C  CD2 . LEU A 1 498 ? 173.696 145.118 129.426 1.00 43.77  ? 491 LEU A CD2 1 
ATOM   3578  N  N   . ALA A 1 499 ? 178.074 145.291 131.347 1.00 46.34  ? 492 ALA A N   1 
ATOM   3579  C  CA  . ALA A 1 499 ? 179.378 144.992 131.985 1.00 46.34  ? 492 ALA A CA  1 
ATOM   3580  C  C   . ALA A 1 499 ? 179.834 143.588 131.579 1.00 46.34  ? 492 ALA A C   1 
ATOM   3581  O  O   . ALA A 1 499 ? 179.066 142.635 131.802 1.00 46.34  ? 492 ALA A O   1 
ATOM   3582  C  CB  . ALA A 1 499 ? 179.257 145.113 133.484 1.00 46.34  ? 492 ALA A CB  1 
ATOM   3583  N  N   . SER A 1 500 ? 181.044 143.477 131.018 1.00 54.45  ? 493 SER A N   1 
ATOM   3584  C  CA  . SER A 1 500 ? 181.597 142.159 130.609 1.00 54.45  ? 493 SER A CA  1 
ATOM   3585  C  C   . SER A 1 500 ? 183.062 142.053 131.058 1.00 54.45  ? 493 SER A C   1 
ATOM   3586  O  O   . SER A 1 500 ? 183.852 142.965 130.725 1.00 54.45  ? 493 SER A O   1 
ATOM   3587  C  CB  . SER A 1 500 ? 181.466 141.953 129.122 1.00 54.45  ? 493 SER A CB  1 
ATOM   3588  O  OG  . SER A 1 500 ? 180.102 141.987 128.723 1.00 54.45  ? 493 SER A OG  1 
ATOM   3589  N  N   . PRO A 1 501 ? 183.460 140.994 131.798 1.00 58.12  ? 494 PRO A N   1 
ATOM   3590  C  CA  . PRO A 1 501 ? 184.826 140.886 132.297 1.00 58.12  ? 494 PRO A CA  1 
ATOM   3591  C  C   . PRO A 1 501 ? 185.842 140.560 131.208 1.00 58.12  ? 494 PRO A C   1 
ATOM   3592  O  O   . PRO A 1 501 ? 187.011 140.978 131.327 1.00 58.12  ? 494 PRO A O   1 
ATOM   3593  C  CB  . PRO A 1 501 ? 184.716 139.765 133.345 1.00 58.12  ? 494 PRO A CB  1 
ATOM   3594  C  CG  . PRO A 1 501 ? 183.572 138.911 132.850 1.00 58.12  ? 494 PRO A CG  1 
ATOM   3595  C  CD  . PRO A 1 501 ? 182.607 139.882 132.188 1.00 58.12  ? 494 PRO A CD  1 
ATOM   3596  N  N   . ARG A 1 502 ? 185.414 139.817 130.182 1.00 30.00  ? 495 ARG A N   1 
ATOM   3597  C  CA  . ARG A 1 502 ? 186.318 139.435 129.066 1.00 30.00  ? 495 ARG A CA  1 
ATOM   3598  C  C   . ARG A 1 502 ? 186.997 140.693 128.504 1.00 30.00  ? 495 ARG A C   1 
ATOM   3599  O  O   . ARG A 1 502 ? 188.234 140.672 128.330 1.00 30.00  ? 495 ARG A O   1 
ATOM   3600  C  CB  . ARG A 1 502 ? 185.509 138.718 127.980 1.00 30.00  ? 495 ARG A CB  1 
ATOM   3601  C  CG  . ARG A 1 502 ? 184.149 139.357 127.735 1.00 30.00  ? 495 ARG A CG  1 
ATOM   3602  C  CD  . ARG A 1 502 ? 183.416 138.750 126.551 1.00 30.00  ? 495 ARG A CD  1 
ATOM   3603  N  NE  . ARG A 1 502 ? 182.050 139.271 126.433 1.00 30.00  ? 495 ARG A NE  1 
ATOM   3604  C  CZ  . ARG A 1 502 ? 181.577 139.924 125.380 1.00 30.00  ? 495 ARG A CZ  1 
ATOM   3605  N  NH1 . ARG A 1 502 ? 182.382 140.240 124.381 1.00 30.00  ? 495 ARG A NH1 1 
ATOM   3606  N  NH2 . ARG A 1 502 ? 180.300 140.259 125.330 1.00 30.00  ? 495 ARG A NH2 1 
ATOM   3607  N  N   . SER A 1 503 ? 186.213 141.738 128.227 1.00 67.59  ? 496 SER A N   1 
ATOM   3608  C  CA  . SER A 1 503 ? 186.773 143.004 127.687 1.00 67.59  ? 496 SER A CA  1 
ATOM   3609  C  C   . SER A 1 503 ? 187.969 143.443 128.543 1.00 67.59  ? 496 SER A C   1 
ATOM   3610  O  O   . SER A 1 503 ? 189.034 143.749 127.963 1.00 67.59  ? 496 SER A O   1 
ATOM   3611  C  CB  . SER A 1 503 ? 185.721 144.084 127.618 1.00 67.59  ? 496 SER A CB  1 
ATOM   3612  O  OG  . SER A 1 503 ? 184.549 143.705 128.328 1.00 67.59  ? 496 SER A OG  1 
ATOM   3613  N  N   . CYS A 1 504 ? 187.797 143.467 129.868 1.00 69.43  ? 497 CYS A N   1 
ATOM   3614  C  CA  . CYS A 1 504 ? 188.896 143.878 130.781 1.00 69.43  ? 497 CYS A CA  1 
ATOM   3615  C  C   . CYS A 1 504 ? 190.064 142.891 130.654 1.00 69.43  ? 497 CYS A C   1 
ATOM   3616  O  O   . CYS A 1 504 ? 191.228 143.349 130.673 1.00 69.43  ? 497 CYS A O   1 
ATOM   3617  C  CB  . CYS A 1 504 ? 188.416 143.926 132.227 1.00 69.43  ? 497 CYS A CB  1 
ATOM   3618  S  SG  . CYS A 1 504 ? 189.263 145.180 133.222 1.00 69.43  ? 497 CYS A SG  1 
ATOM   3619  N  N   . TYR A 1 505 ? 189.764 141.595 130.528 1.00 74.30  ? 498 TYR A N   1 
ATOM   3620  C  CA  . TYR A 1 505 ? 190.824 140.595 130.456 1.00 74.30  ? 498 TYR A CA  1 
ATOM   3621  C  C   . TYR A 1 505 ? 191.616 140.711 129.158 1.00 74.30  ? 498 TYR A C   1 
ATOM   3622  O  O   . TYR A 1 505 ? 192.837 140.530 129.158 1.00 74.30  ? 498 TYR A O   1 
ATOM   3623  C  CB  . TYR A 1 505 ? 190.242 139.195 130.624 1.00 74.30  ? 498 TYR A CB  1 
ATOM   3624  C  CG  . TYR A 1 505 ? 190.159 138.776 132.072 1.00 74.30  ? 498 TYR A CG  1 
ATOM   3625  C  CD1 . TYR A 1 505 ? 191.304 138.659 132.845 1.00 74.30  ? 498 TYR A CD1 1 
ATOM   3626  C  CD2 . TYR A 1 505 ? 188.936 138.510 132.670 1.00 74.30  ? 498 TYR A CD2 1 
ATOM   3627  C  CE1 . TYR A 1 505 ? 191.236 138.282 134.169 1.00 74.30  ? 498 TYR A CE1 1 
ATOM   3628  C  CE2 . TYR A 1 505 ? 188.857 138.133 133.993 1.00 74.30  ? 498 TYR A CE2 1 
ATOM   3629  C  CZ  . TYR A 1 505 ? 190.010 138.020 134.738 1.00 74.30  ? 498 TYR A CZ  1 
ATOM   3630  O  OH  . TYR A 1 505 ? 189.938 137.643 136.058 1.00 74.30  ? 498 TYR A OH  1 
ATOM   3631  N  N   . LYS A 1 506 ? 190.951 141.021 128.044 1.00 76.71  ? 499 LYS A N   1 
ATOM   3632  C  CA  . LYS A 1 506 ? 191.683 141.208 126.794 1.00 76.71  ? 499 LYS A CA  1 
ATOM   3633  C  C   . LYS A 1 506 ? 192.527 142.478 126.840 1.00 76.71  ? 499 LYS A C   1 
ATOM   3634  O  O   . LYS A 1 506 ? 193.661 142.495 126.341 1.00 76.71  ? 499 LYS A O   1 
ATOM   3635  C  CB  . LYS A 1 506 ? 190.715 141.214 125.606 1.00 76.71  ? 499 LYS A CB  1 
ATOM   3636  C  CG  . LYS A 1 506 ? 190.294 142.582 125.099 1.00 76.71  ? 499 LYS A CG  1 
ATOM   3637  C  CD  . LYS A 1 506 ? 189.798 142.511 123.663 1.00 76.71  ? 499 LYS A CD  1 
ATOM   3638  C  CE  . LYS A 1 506 ? 188.593 141.593 123.537 1.00 76.71  ? 499 LYS A CE  1 
ATOM   3639  N  NZ  . LYS A 1 506 ? 187.996 141.645 122.174 1.00 76.71  ? 499 LYS A NZ  1 
ATOM   3640  N  N   . LEU A 1 507 ? 192.009 143.542 127.462 1.00 78.33  ? 500 LEU A N   1 
ATOM   3641  C  CA  . LEU A 1 507 ? 192.813 144.747 127.637 1.00 78.33  ? 500 LEU A CA  1 
ATOM   3642  C  C   . LEU A 1 507 ? 194.052 144.456 128.470 1.00 78.33  ? 500 LEU A C   1 
ATOM   3643  O  O   . LEU A 1 507 ? 195.152 144.920 128.150 1.00 78.33  ? 500 LEU A O   1 
ATOM   3644  C  CB  . LEU A 1 507 ? 191.980 145.847 128.293 1.00 78.33  ? 500 LEU A CB  1 
ATOM   3645  C  CG  . LEU A 1 507 ? 192.687 147.161 128.616 1.00 78.33  ? 500 LEU A CG  1 
ATOM   3646  C  CD1 . LEU A 1 507 ? 193.167 147.817 127.337 1.00 78.33  ? 500 LEU A CD1 1 
ATOM   3647  C  CD2 . LEU A 1 507 ? 191.754 148.087 129.376 1.00 78.33  ? 500 LEU A CD2 1 
ATOM   3648  N  N   . PHE A 1 508 ? 193.893 143.679 129.542 1.00 83.36  ? 501 PHE A N   1 
ATOM   3649  C  CA  . PHE A 1 508 ? 195.028 143.358 130.397 1.00 83.36  ? 501 PHE A CA  1 
ATOM   3650  C  C   . PHE A 1 508 ? 196.015 142.440 129.686 1.00 83.36  ? 501 PHE A C   1 
ATOM   3651  O  O   . PHE A 1 508 ? 197.229 142.561 129.879 1.00 83.36  ? 501 PHE A O   1 
ATOM   3652  C  CB  . PHE A 1 508 ? 194.532 142.732 131.697 1.00 83.36  ? 501 PHE A CB  1 
ATOM   3653  C  CG  . PHE A 1 508 ? 193.950 143.726 132.659 1.00 83.36  ? 501 PHE A CG  1 
ATOM   3654  C  CD1 . PHE A 1 508 ? 194.018 145.082 132.396 1.00 83.36  ? 501 PHE A CD1 1 
ATOM   3655  C  CD2 . PHE A 1 508 ? 193.334 143.305 133.821 1.00 83.36  ? 501 PHE A CD2 1 
ATOM   3656  C  CE1 . PHE A 1 508 ? 193.486 145.998 133.274 1.00 83.36  ? 501 PHE A CE1 1 
ATOM   3657  C  CE2 . PHE A 1 508 ? 192.799 144.217 134.704 1.00 83.36  ? 501 PHE A CE2 1 
ATOM   3658  C  CZ  . PHE A 1 508 ? 192.874 145.566 134.430 1.00 83.36  ? 501 PHE A CZ  1 
ATOM   3659  N  N   . GLN A 1 509 ? 195.516 141.520 128.859 1.00 88.04  ? 502 GLN A N   1 
ATOM   3660  C  CA  . GLN A 1 509 ? 196.405 140.678 128.066 1.00 88.04  ? 502 GLN A CA  1 
ATOM   3661  C  C   . GLN A 1 509 ? 197.243 141.521 127.114 1.00 88.04  ? 502 GLN A C   1 
ATOM   3662  O  O   . GLN A 1 509 ? 198.449 141.293 126.960 1.00 88.04  ? 502 GLN A O   1 
ATOM   3663  C  CB  . GLN A 1 509 ? 195.594 139.637 127.293 1.00 88.04  ? 502 GLN A CB  1 
ATOM   3664  C  CG  . GLN A 1 509 ? 195.244 138.391 128.088 1.00 88.04  ? 502 GLN A CG  1 
ATOM   3665  C  CD  . GLN A 1 509 ? 196.447 137.787 128.784 1.00 88.04  ? 502 GLN A CD  1 
ATOM   3666  O  OE1 . GLN A 1 509 ? 196.525 137.770 130.011 1.00 88.04  ? 502 GLN A OE1 1 
ATOM   3667  N  NE2 . GLN A 1 509 ? 197.395 137.289 127.999 1.00 88.04  ? 502 GLN A NE2 1 
ATOM   3668  N  N   . GLU A 1 510 ? 196.615 142.504 126.463 1.00 92.57  ? 503 GLU A N   1 
ATOM   3669  C  CA  . GLU A 1 510 ? 197.371 143.404 125.596 1.00 92.57  ? 503 GLU A CA  1 
ATOM   3670  C  C   . GLU A 1 510 ? 198.392 144.211 126.391 1.00 92.57  ? 503 GLU A C   1 
ATOM   3671  O  O   . GLU A 1 510 ? 199.550 144.348 125.977 1.00 92.57  ? 503 GLU A O   1 
ATOM   3672  C  CB  . GLU A 1 510 ? 196.422 144.333 124.841 1.00 92.57  ? 503 GLU A CB  1 
ATOM   3673  C  CG  . GLU A 1 510 ? 195.407 143.611 123.975 1.00 92.57  ? 503 GLU A CG  1 
ATOM   3674  C  CD  . GLU A 1 510 ? 196.058 142.783 122.885 1.00 92.57  ? 503 GLU A CD  1 
ATOM   3675  O  OE1 . GLU A 1 510 ? 196.303 143.330 121.789 1.00 92.57  ? 503 GLU A OE1 1 
ATOM   3676  O  OE2 . GLU A 1 510 ? 196.322 141.585 123.121 1.00 92.57  ? 503 GLU A OE2 1 
ATOM   3677  N  N   . GLN A 1 511 ? 197.987 144.741 127.545 1.00 95.34  ? 504 GLN A N   1 
ATOM   3678  C  CA  . GLN A 1 511 ? 198.915 145.525 128.351 1.00 95.34  ? 504 GLN A CA  1 
ATOM   3679  C  C   . GLN A 1 511 ? 200.098 144.686 128.817 1.00 95.34  ? 504 GLN A C   1 
ATOM   3680  O  O   . GLN A 1 511 ? 201.215 145.202 128.938 1.00 95.34  ? 504 GLN A O   1 
ATOM   3681  C  CB  . GLN A 1 511 ? 198.187 146.136 129.547 1.00 95.34  ? 504 GLN A CB  1 
ATOM   3682  C  CG  . GLN A 1 511 ? 197.167 147.198 129.171 1.00 95.34  ? 504 GLN A CG  1 
ATOM   3683  C  CD  . GLN A 1 511 ? 197.699 148.176 128.145 1.00 95.34  ? 504 GLN A CD  1 
ATOM   3684  O  OE1 . GLN A 1 511 ? 198.684 148.873 128.387 1.00 95.34  ? 504 GLN A OE1 1 
ATOM   3685  N  NE2 . GLN A 1 511 ? 197.050 148.231 126.988 1.00 95.34  ? 504 GLN A NE2 1 
ATOM   3686  N  N   . GLN A 1 512 ? 199.876 143.399 129.090 1.00 99.06  ? 505 GLN A N   1 
ATOM   3687  C  CA  . GLN A 1 512 ? 200.975 142.538 129.512 1.00 99.06  ? 505 GLN A CA  1 
ATOM   3688  C  C   . GLN A 1 512 ? 201.886 142.182 128.343 1.00 99.06  ? 505 GLN A C   1 
ATOM   3689  O  O   . GLN A 1 512 ? 203.115 142.229 128.469 1.00 99.06  ? 505 GLN A O   1 
ATOM   3690  C  CB  . GLN A 1 512 ? 200.436 141.271 130.176 1.00 99.06  ? 505 GLN A CB  1 
ATOM   3691  C  CG  . GLN A 1 512 ? 201.520 140.450 130.859 1.00 99.06  ? 505 GLN A CG  1 
ATOM   3692  C  CD  . GLN A 1 512 ? 201.016 139.121 131.381 1.00 99.06  ? 505 GLN A CD  1 
ATOM   3693  O  OE1 . GLN A 1 512 ? 200.572 138.267 130.616 1.00 99.06  ? 505 GLN A OE1 1 
ATOM   3694  N  NE2 . GLN A 1 512 ? 201.090 138.938 132.695 1.00 99.06  ? 505 GLN A NE2 1 
ATOM   3695  N  N   . ASN A 1 513 ? 201.308 141.823 127.193 1.00 100.57 ? 506 ASN A N   1 
ATOM   3696  C  CA  . ASN A 1 513 ? 202.142 141.325 126.105 1.00 100.57 ? 506 ASN A CA  1 
ATOM   3697  C  C   . ASN A 1 513 ? 202.752 142.431 125.250 1.00 100.57 ? 506 ASN A C   1 
ATOM   3698  O  O   . ASN A 1 513 ? 203.585 142.129 124.389 1.00 100.57 ? 506 ASN A O   1 
ATOM   3699  C  CB  . ASN A 1 513 ? 201.357 140.327 125.237 1.00 100.57 ? 506 ASN A CB  1 
ATOM   3700  C  CG  . ASN A 1 513 ? 200.268 140.976 124.406 1.00 100.57 ? 506 ASN A CG  1 
ATOM   3701  O  OD1 . ASN A 1 513 ? 200.045 142.179 124.472 1.00 100.57 ? 506 ASN A OD1 1 
ATOM   3702  N  ND2 . ASN A 1 513 ? 199.577 140.167 123.611 1.00 100.57 ? 506 ASN A ND2 1 
ATOM   3703  N  N   . GLU A 1 514 ? 202.372 143.693 125.458 1.00 104.69 ? 507 GLU A N   1 
ATOM   3704  C  CA  . GLU A 1 514 ? 203.197 144.789 124.960 1.00 104.69 ? 507 GLU A CA  1 
ATOM   3705  C  C   . GLU A 1 514 ? 204.331 145.159 125.910 1.00 104.69 ? 507 GLU A C   1 
ATOM   3706  O  O   . GLU A 1 514 ? 205.106 146.068 125.594 1.00 104.69 ? 507 GLU A O   1 
ATOM   3707  C  CB  . GLU A 1 514 ? 202.352 146.032 124.652 1.00 104.69 ? 507 GLU A CB  1 
ATOM   3708  C  CG  . GLU A 1 514 ? 201.803 146.100 123.224 1.00 104.69 ? 507 GLU A CG  1 
ATOM   3709  C  CD  . GLU A 1 514 ? 200.985 144.896 122.809 1.00 104.69 ? 507 GLU A CD  1 
ATOM   3710  O  OE1 . GLU A 1 514 ? 201.373 144.227 121.829 1.00 104.69 ? 507 GLU A OE1 1 
ATOM   3711  O  OE2 . GLU A 1 514 ? 199.925 144.656 123.415 1.00 104.69 ? 507 GLU A OE2 1 
ATOM   3712  N  N   . GLY A 1 515 ? 204.451 144.488 127.053 1.00 106.77 ? 508 GLY A N   1 
ATOM   3713  C  CA  . GLY A 1 515 ? 205.603 144.642 127.917 1.00 106.77 ? 508 GLY A CA  1 
ATOM   3714  C  C   . GLY A 1 515 ? 205.418 145.543 129.118 1.00 106.77 ? 508 GLY A C   1 
ATOM   3715  O  O   . GLY A 1 515 ? 206.391 145.778 129.844 1.00 106.77 ? 508 GLY A O   1 
ATOM   3716  N  N   . HIS A 1 516 ? 204.212 146.054 129.354 1.00 107.41 ? 509 HIS A N   1 
ATOM   3717  C  CA  . HIS A 1 516 ? 203.942 146.939 130.485 1.00 107.41 ? 509 HIS A CA  1 
ATOM   3718  C  C   . HIS A 1 516 ? 203.195 146.227 131.603 1.00 107.41 ? 509 HIS A C   1 
ATOM   3719  O  O   . HIS A 1 516 ? 202.300 146.801 132.229 1.00 107.41 ? 509 HIS A O   1 
ATOM   3720  C  CB  . HIS A 1 516 ? 203.178 148.179 130.029 1.00 107.41 ? 509 HIS A CB  1 
ATOM   3721  C  CG  . HIS A 1 516 ? 203.571 148.669 128.670 1.00 107.41 ? 509 HIS A CG  1 
ATOM   3722  N  ND1 . HIS A 1 516 ? 203.222 148.015 127.508 1.00 107.41 ? 509 HIS A ND1 1 
ATOM   3723  C  CD2 . HIS A 1 516 ? 204.297 149.747 128.290 1.00 107.41 ? 509 HIS A CD2 1 
ATOM   3724  C  CE1 . HIS A 1 516 ? 203.708 148.673 126.471 1.00 107.41 ? 509 HIS A CE1 1 
ATOM   3725  N  NE2 . HIS A 1 516 ? 204.365 149.728 126.918 1.00 107.41 ? 509 HIS A NE2 1 
ATOM   3726  N  N   . GLY A 1 517 ? 203.545 144.968 131.874 1.00 103.51 ? 510 GLY A N   1 
ATOM   3727  C  CA  . GLY A 1 517 ? 202.938 144.249 132.981 1.00 103.51 ? 510 GLY A CA  1 
ATOM   3728  C  C   . GLY A 1 517 ? 203.274 144.823 134.342 1.00 103.51 ? 510 GLY A C   1 
ATOM   3729  O  O   . GLY A 1 517 ? 202.644 144.448 135.336 1.00 103.51 ? 510 GLY A O   1 
ATOM   3730  N  N   . GLU A 1 518 ? 204.258 145.719 134.413 1.00 104.03 ? 511 GLU A N   1 
ATOM   3731  C  CA  . GLU A 1 518 ? 204.620 146.364 135.668 1.00 104.03 ? 511 GLU A CA  1 
ATOM   3732  C  C   . GLU A 1 518 ? 203.598 147.395 136.127 1.00 104.03 ? 511 GLU A C   1 
ATOM   3733  O  O   . GLU A 1 518 ? 203.718 147.897 137.249 1.00 104.03 ? 511 GLU A O   1 
ATOM   3734  C  CB  . GLU A 1 518 ? 205.990 147.037 135.539 1.00 104.03 ? 511 GLU A CB  1 
ATOM   3735  C  CG  . GLU A 1 518 ? 207.106 146.119 135.068 1.00 104.03 ? 511 GLU A CG  1 
ATOM   3736  C  CD  . GLU A 1 518 ? 207.606 145.198 136.164 1.00 104.03 ? 511 GLU A CD  1 
ATOM   3737  O  OE1 . GLU A 1 518 ? 207.973 145.705 137.245 1.00 104.03 ? 511 GLU A OE1 1 
ATOM   3738  O  OE2 . GLU A 1 518 ? 207.641 143.971 135.942 1.00 104.03 ? 511 GLU A OE2 1 
ATOM   3739  N  N   . ALA A 1 519 ? 202.613 147.729 135.293 1.00 101.64 ? 512 ALA A N   1 
ATOM   3740  C  CA  . ALA A 1 519 ? 201.639 148.753 135.648 1.00 101.64 ? 512 ALA A CA  1 
ATOM   3741  C  C   . ALA A 1 519 ? 200.873 148.360 136.904 1.00 101.64 ? 512 ALA A C   1 
ATOM   3742  O  O   . ALA A 1 519 ? 200.467 147.206 137.071 1.00 101.64 ? 512 ALA A O   1 
ATOM   3743  C  CB  . ALA A 1 519 ? 200.668 148.983 134.490 1.00 101.64 ? 512 ALA A CB  1 
ATOM   3744  N  N   . LEU A 1 520 ? 200.677 149.330 137.792 1.00 99.92  ? 513 LEU A N   1 
ATOM   3745  C  CA  . LEU A 1 520 ? 200.036 149.104 139.079 1.00 99.92  ? 513 LEU A CA  1 
ATOM   3746  C  C   . LEU A 1 520 ? 198.635 149.700 139.075 1.00 99.92  ? 513 LEU A C   1 
ATOM   3747  O  O   . LEU A 1 520 ? 198.469 150.909 138.886 1.00 99.92  ? 513 LEU A O   1 
ATOM   3748  C  CB  . LEU A 1 520 ? 200.860 149.713 140.217 1.00 99.92  ? 513 LEU A CB  1 
ATOM   3749  C  CG  . LEU A 1 520 ? 202.232 149.096 140.495 1.00 99.92  ? 513 LEU A CG  1 
ATOM   3750  C  CD1 . LEU A 1 520 ? 203.326 149.878 139.786 1.00 99.92  ? 513 LEU A CD1 1 
ATOM   3751  C  CD2 . LEU A 1 520 ? 202.499 149.030 141.990 1.00 99.92  ? 513 LEU A CD2 1 
ATOM   3752  N  N   . LEU A 1 521 ? 197.637 148.849 139.285 1.00 96.64  ? 514 LEU A N   1 
ATOM   3753  C  CA  . LEU A 1 521 ? 196.263 149.282 139.471 1.00 96.64  ? 514 LEU A CA  1 
ATOM   3754  C  C   . LEU A 1 521 ? 196.099 149.826 140.883 1.00 96.64  ? 514 LEU A C   1 
ATOM   3755  O  O   . LEU A 1 521 ? 196.702 149.310 141.833 1.00 96.64  ? 514 LEU A O   1 
ATOM   3756  C  CB  . LEU A 1 521 ? 195.298 148.119 139.229 1.00 96.64  ? 514 LEU A CB  1 
ATOM   3757  C  CG  . LEU A 1 521 ? 193.895 148.398 138.680 1.00 96.64  ? 514 LEU A CG  1 
ATOM   3758  C  CD1 . LEU A 1 521 ? 193.305 147.127 138.096 1.00 96.64  ? 514 LEU A CD1 1 
ATOM   3759  C  CD2 . LEU A 1 521 ? 192.973 148.957 139.747 1.00 96.64  ? 514 LEU A CD2 1 
ATOM   3760  N  N   . PHE A 1 522 ? 195.272 150.872 141.003 1.00 98.26  ? 515 PHE A N   1 
ATOM   3761  C  CA  . PHE A 1 522 ? 195.044 151.613 142.247 1.00 98.26  ? 515 PHE A CA  1 
ATOM   3762  C  C   . PHE A 1 522 ? 196.288 152.400 142.659 1.00 98.26  ? 515 PHE A C   1 
ATOM   3763  O  O   . PHE A 1 522 ? 196.653 152.441 143.834 1.00 98.26  ? 515 PHE A O   1 
ATOM   3764  C  CB  . PHE A 1 522 ? 194.578 150.696 143.382 1.00 98.26  ? 515 PHE A CB  1 
ATOM   3765  C  CG  . PHE A 1 522 ? 193.247 150.053 143.130 1.00 98.26  ? 515 PHE A CG  1 
ATOM   3766  C  CD1 . PHE A 1 522 ? 192.174 150.803 142.685 1.00 98.26  ? 515 PHE A CD1 1 
ATOM   3767  C  CD2 . PHE A 1 522 ? 193.067 148.698 143.345 1.00 98.26  ? 515 PHE A CD2 1 
ATOM   3768  C  CE1 . PHE A 1 522 ? 190.949 150.211 142.452 1.00 98.26  ? 515 PHE A CE1 1 
ATOM   3769  C  CE2 . PHE A 1 522 ? 191.843 148.103 143.116 1.00 98.26  ? 515 PHE A CE2 1 
ATOM   3770  C  CZ  . PHE A 1 522 ? 190.782 148.861 142.669 1.00 98.26  ? 515 PHE A CZ  1 
ATOM   3771  N  N   . GLU A 1 523 ? 196.942 153.029 141.681 1.00 101.02 ? 516 GLU A N   1 
ATOM   3772  C  CA  . GLU A 1 523 ? 198.107 153.854 141.982 1.00 101.02 ? 516 GLU A CA  1 
ATOM   3773  C  C   . GLU A 1 523 ? 197.705 155.160 142.657 1.00 101.02 ? 516 GLU A C   1 
ATOM   3774  O  O   . GLU A 1 523 ? 198.358 155.597 143.611 1.00 101.02 ? 516 GLU A O   1 
ATOM   3775  C  CB  . GLU A 1 523 ? 198.897 154.134 140.705 1.00 101.02 ? 516 GLU A CB  1 
ATOM   3776  C  CG  . GLU A 1 523 ? 198.037 154.246 139.460 1.00 101.02 ? 516 GLU A CG  1 
ATOM   3777  C  CD  . GLU A 1 523 ? 198.861 154.391 138.198 1.00 101.02 ? 516 GLU A CD  1 
ATOM   3778  O  OE1 . GLU A 1 523 ? 199.678 155.332 138.124 1.00 101.02 ? 516 GLU A OE1 1 
ATOM   3779  O  OE2 . GLU A 1 523 ? 198.697 153.558 137.283 1.00 101.02 ? 516 GLU A OE2 1 
ATOM   3780  N  N   . GLY A 1 524 ? 196.639 155.799 142.170 1.00 103.64 ? 517 GLY A N   1 
ATOM   3781  C  CA  . GLY A 1 524 ? 196.218 157.064 142.750 1.00 103.64 ? 517 GLY A CA  1 
ATOM   3782  C  C   . GLY A 1 524 ? 195.779 156.931 144.196 1.00 103.64 ? 517 GLY A C   1 
ATOM   3783  O  O   . GLY A 1 524 ? 196.054 157.805 145.022 1.00 103.64 ? 517 GLY A O   1 
ATOM   3784  N  N   . ILE A 1 525 ? 195.092 155.842 144.519 1.00 107.64 ? 518 ILE A N   1 
ATOM   3785  C  CA  . ILE A 1 525 ? 194.646 155.596 145.886 1.00 107.64 ? 518 ILE A CA  1 
ATOM   3786  C  C   . ILE A 1 525 ? 195.819 155.068 146.700 1.00 107.64 ? 518 ILE A C   1 
ATOM   3787  O  O   . ILE A 1 525 ? 196.490 154.110 146.299 1.00 107.64 ? 518 ILE A O   1 
ATOM   3788  C  CB  . ILE A 1 525 ? 193.466 154.612 145.902 1.00 107.64 ? 518 ILE A CB  1 
ATOM   3789  C  CG1 . ILE A 1 525 ? 192.252 155.219 145.195 1.00 107.64 ? 518 ILE A CG1 1 
ATOM   3790  C  CG2 . ILE A 1 525 ? 193.119 154.218 147.328 1.00 107.64 ? 518 ILE A CG2 1 
ATOM   3791  C  CD1 . ILE A 1 525 ? 192.027 156.685 145.501 1.00 107.64 ? 518 ILE A CD1 1 
ATOM   3792  N  N   . LYS A 1 526 ? 196.070 155.694 147.849 1.00 112.01 ? 519 LYS A N   1 
ATOM   3793  C  CA  . LYS A 1 526 ? 197.188 155.328 148.709 1.00 112.01 ? 519 LYS A CA  1 
ATOM   3794  C  C   . LYS A 1 526 ? 196.820 154.291 149.761 1.00 112.01 ? 519 LYS A C   1 
ATOM   3795  O  O   . LYS A 1 526 ? 197.615 153.386 150.033 1.00 112.01 ? 519 LYS A O   1 
ATOM   3796  C  CB  . LYS A 1 526 ? 197.749 156.574 149.403 1.00 112.01 ? 519 LYS A CB  1 
ATOM   3797  C  CG  . LYS A 1 526 ? 198.287 157.627 148.449 1.00 112.01 ? 519 LYS A CG  1 
ATOM   3798  C  CD  . LYS A 1 526 ? 198.867 158.811 149.206 1.00 112.01 ? 519 LYS A CD  1 
ATOM   3799  C  CE  . LYS A 1 526 ? 199.362 159.887 148.253 1.00 112.01 ? 519 LYS A CE  1 
ATOM   3800  N  NZ  . LYS A 1 526 ? 199.934 161.052 148.982 1.00 112.01 ? 519 LYS A NZ  1 
ATOM   3801  N  N   . LYS A 1 527 ? 195.635 154.406 150.366 1.00 108.69 ? 520 LYS A N   1 
ATOM   3802  C  CA  . LYS A 1 527 ? 195.243 153.465 151.411 1.00 108.69 ? 520 LYS A CA  1 
ATOM   3803  C  C   . LYS A 1 527 ? 195.089 152.052 150.861 1.00 108.69 ? 520 LYS A C   1 
ATOM   3804  O  O   . LYS A 1 527 ? 195.573 151.089 151.468 1.00 108.69 ? 520 LYS A O   1 
ATOM   3805  C  CB  . LYS A 1 527 ? 193.946 153.926 152.073 1.00 108.69 ? 520 LYS A CB  1 
ATOM   3806  C  CG  . LYS A 1 527 ? 194.020 155.316 152.683 1.00 108.69 ? 520 LYS A CG  1 
ATOM   3807  C  CD  . LYS A 1 527 ? 192.758 155.642 153.466 1.00 108.69 ? 520 LYS A CD  1 
ATOM   3808  C  CE  . LYS A 1 527 ? 192.674 157.126 153.785 1.00 108.69 ? 520 LYS A CE  1 
ATOM   3809  N  NZ  . LYS A 1 527 ? 191.383 157.482 154.436 1.00 108.69 ? 520 LYS A NZ  1 
ATOM   3810  N  N   . LYS A 1 528 ? 194.424 151.905 149.720 1.00 106.14 ? 521 LYS A N   1 
ATOM   3811  C  CA  . LYS A 1 528 ? 194.236 150.586 149.136 1.00 106.14 ? 521 LYS A CA  1 
ATOM   3812  C  C   . LYS A 1 528 ? 195.524 150.103 148.477 1.00 106.14 ? 521 LYS A C   1 
ATOM   3813  O  O   . LYS A 1 528 ? 196.301 150.887 147.926 1.00 106.14 ? 521 LYS A O   1 
ATOM   3814  C  CB  . LYS A 1 528 ? 193.098 150.606 148.116 1.00 106.14 ? 521 LYS A CB  1 
ATOM   3815  C  CG  . LYS A 1 528 ? 192.536 149.230 147.795 1.00 106.14 ? 521 LYS A CG  1 
ATOM   3816  C  CD  . LYS A 1 528 ? 191.272 149.326 146.959 1.00 106.14 ? 521 LYS A CD  1 
ATOM   3817  C  CE  . LYS A 1 528 ? 190.487 148.025 146.997 1.00 106.14 ? 521 LYS A CE  1 
ATOM   3818  N  NZ  . LYS A 1 528 ? 189.151 148.161 146.353 1.00 106.14 ? 521 LYS A NZ  1 
ATOM   3819  N  N   . LYS A 1 529 ? 195.744 148.794 148.544 1.00 109.51 ? 522 LYS A N   1 
ATOM   3820  C  CA  . LYS A 1 529 ? 196.956 148.210 147.988 1.00 109.51 ? 522 LYS A CA  1 
ATOM   3821  C  C   . LYS A 1 529 ? 196.928 148.249 146.466 1.00 109.51 ? 522 LYS A C   1 
ATOM   3822  O  O   . LYS A 1 529 ? 195.902 147.974 145.837 1.00 109.51 ? 522 LYS A O   1 
ATOM   3823  C  CB  . LYS A 1 529 ? 197.119 146.769 148.473 1.00 109.51 ? 522 LYS A CB  1 
ATOM   3824  C  CG  . LYS A 1 529 ? 197.155 146.626 149.985 1.00 109.51 ? 522 LYS A CG  1 
ATOM   3825  C  CD  . LYS A 1 529 ? 197.315 145.173 150.398 1.00 109.51 ? 522 LYS A CD  1 
ATOM   3826  C  CE  . LYS A 1 529 ? 197.313 145.028 151.911 1.00 109.51 ? 522 LYS A CE  1 
ATOM   3827  N  NZ  . LYS A 1 529 ? 197.493 143.612 152.333 1.00 109.51 ? 522 LYS A NZ  1 
ATOM   3828  N  N   . GLN A 1 530 ? 198.068 148.594 145.875 1.00 104.82 ? 523 GLN A N   1 
ATOM   3829  C  CA  . GLN A 1 530 ? 198.234 148.578 144.429 1.00 104.82 ? 523 GLN A CA  1 
ATOM   3830  C  C   . GLN A 1 530 ? 198.499 147.152 143.968 1.00 104.82 ? 523 GLN A C   1 
ATOM   3831  O  O   . GLN A 1 530 ? 199.222 146.401 144.629 1.00 104.82 ? 523 GLN A O   1 
ATOM   3832  C  CB  . GLN A 1 530 ? 199.390 149.489 144.015 1.00 104.82 ? 523 GLN A CB  1 
ATOM   3833  C  CG  . GLN A 1 530 ? 199.618 150.657 144.962 1.00 104.82 ? 523 GLN A CG  1 
ATOM   3834  C  CD  . GLN A 1 530 ? 200.721 151.585 144.493 1.00 104.82 ? 523 GLN A CD  1 
ATOM   3835  O  OE1 . GLN A 1 530 ? 200.470 152.564 143.791 1.00 104.82 ? 523 GLN A OE1 1 
ATOM   3836  N  NE2 . GLN A 1 530 ? 201.953 151.280 144.882 1.00 104.82 ? 523 GLN A NE2 1 
ATOM   3837  N  N   . GLN A 1 531 ? 197.913 146.776 142.832 1.00 99.04  ? 524 GLN A N   1 
ATOM   3838  C  CA  . GLN A 1 531 ? 198.042 145.410 142.333 1.00 99.04  ? 524 GLN A CA  1 
ATOM   3839  C  C   . GLN A 1 531 ? 198.688 145.411 140.957 1.00 99.04  ? 524 GLN A C   1 
ATOM   3840  O  O   . GLN A 1 531 ? 198.294 146.188 140.084 1.00 99.04  ? 524 GLN A O   1 
ATOM   3841  C  CB  . GLN A 1 531 ? 196.685 144.701 142.281 1.00 99.04  ? 524 GLN A CB  1 
ATOM   3842  C  CG  . GLN A 1 531 ? 196.022 144.554 143.638 1.00 99.04  ? 524 GLN A CG  1 
ATOM   3843  C  CD  . GLN A 1 531 ? 194.616 144.000 143.546 1.00 99.04  ? 524 GLN A CD  1 
ATOM   3844  O  OE1 . GLN A 1 531 ? 194.409 142.877 143.087 1.00 99.04  ? 524 GLN A OE1 1 
ATOM   3845  N  NE2 . GLN A 1 531 ? 193.640 144.785 143.986 1.00 99.04  ? 524 GLN A NE2 1 
ATOM   3846  N  N   . LYS A 1 532 ? 199.675 144.542 140.765 1.00 98.56  ? 525 LYS A N   1 
ATOM   3847  C  CA  . LYS A 1 532 ? 200.378 144.484 139.495 1.00 98.56  ? 525 LYS A CA  1 
ATOM   3848  C  C   . LYS A 1 532 ? 199.616 143.605 138.504 1.00 98.56  ? 525 LYS A C   1 
ATOM   3849  O  O   . LYS A 1 532 ? 198.769 142.790 138.878 1.00 98.56  ? 525 LYS A O   1 
ATOM   3850  C  CB  . LYS A 1 532 ? 201.802 143.969 139.697 1.00 98.56  ? 525 LYS A CB  1 
ATOM   3851  C  CG  . LYS A 1 532 ? 202.636 144.857 140.615 1.00 98.56  ? 525 LYS A CG  1 
ATOM   3852  C  CD  . LYS A 1 532 ? 203.954 144.207 141.006 1.00 98.56  ? 525 LYS A CD  1 
ATOM   3853  C  CE  . LYS A 1 532 ? 204.697 143.672 139.795 1.00 98.56  ? 525 LYS A CE  1 
ATOM   3854  N  NZ  . LYS A 1 532 ? 204.805 144.706 138.727 1.00 98.56  ? 525 LYS A NZ  1 
ATOM   3855  N  N   . ILE A 1 533 ? 199.934 143.783 137.220 1.00 94.13  ? 526 ILE A N   1 
ATOM   3856  C  CA  . ILE A 1 533 ? 199.154 143.149 136.159 1.00 94.13  ? 526 ILE A CA  1 
ATOM   3857  C  C   . ILE A 1 533 ? 199.345 141.635 136.166 1.00 94.13  ? 526 ILE A C   1 
ATOM   3858  O  O   . ILE A 1 533 ? 198.391 140.876 135.951 1.00 94.13  ? 526 ILE A O   1 
ATOM   3859  C  CB  . ILE A 1 533 ? 199.519 143.766 134.796 1.00 94.13  ? 526 ILE A CB  1 
ATOM   3860  C  CG1 . ILE A 1 533 ? 198.934 145.173 134.677 1.00 94.13  ? 526 ILE A CG1 1 
ATOM   3861  C  CG2 . ILE A 1 533 ? 199.022 142.896 133.655 1.00 94.13  ? 526 ILE A CG2 1 
ATOM   3862  C  CD1 . ILE A 1 533 ? 197.429 145.199 134.556 1.00 94.13  ? 526 ILE A CD1 1 
ATOM   3863  N  N   . LYS A 1 534 ? 200.573 141.168 136.404 1.00 93.70  ? 527 LYS A N   1 
ATOM   3864  C  CA  . LYS A 1 534 ? 200.827 139.731 136.356 1.00 93.70  ? 527 LYS A CA  1 
ATOM   3865  C  C   . LYS A 1 534 ? 200.036 138.983 137.422 1.00 93.70  ? 527 LYS A C   1 
ATOM   3866  O  O   . LYS A 1 534 ? 199.488 137.909 137.152 1.00 93.70  ? 527 LYS A O   1 
ATOM   3867  C  CB  . LYS A 1 534 ? 202.321 139.443 136.499 1.00 93.70  ? 527 LYS A CB  1 
ATOM   3868  C  CG  . LYS A 1 534 ? 203.233 140.458 135.838 1.00 93.70  ? 527 LYS A CG  1 
ATOM   3869  C  CD  . LYS A 1 534 ? 204.578 140.520 136.541 1.00 93.70  ? 527 LYS A CD  1 
ATOM   3870  C  CE  . LYS A 1 534 ? 205.395 141.707 136.064 1.00 93.70  ? 527 LYS A CE  1 
ATOM   3871  N  NZ  . LYS A 1 534 ? 204.740 143.001 136.381 1.00 93.70  ? 527 LYS A NZ  1 
ATOM   3872  N  N   . ASN A 1 535 ? 199.965 139.530 138.637 1.00 92.69  ? 528 ASN A N   1 
ATOM   3873  C  CA  . ASN A 1 535 ? 199.255 138.839 139.711 1.00 92.69  ? 528 ASN A CA  1 
ATOM   3874  C  C   . ASN A 1 535 ? 197.768 138.713 139.402 1.00 92.69  ? 528 ASN A C   1 
ATOM   3875  O  O   . ASN A 1 535 ? 197.178 137.636 139.560 1.00 92.69  ? 528 ASN A O   1 
ATOM   3876  C  CB  . ASN A 1 535 ? 199.468 139.567 141.039 1.00 92.69  ? 528 ASN A CB  1 
ATOM   3877  C  CG  . ASN A 1 535 ? 200.876 140.100 141.192 1.00 92.69  ? 528 ASN A CG  1 
ATOM   3878  O  OD1 . ASN A 1 535 ? 201.089 141.309 141.272 1.00 92.69  ? 528 ASN A OD1 1 
ATOM   3879  N  ND2 . ASN A 1 535 ? 201.849 139.198 141.238 1.00 92.69  ? 528 ASN A ND2 1 
ATOM   3880  N  N   . ILE A 1 536 ? 197.143 139.803 138.953 1.00 87.31  ? 529 ILE A N   1 
ATOM   3881  C  CA  . ILE A 1 536 ? 195.711 139.763 138.672 1.00 87.31  ? 529 ILE A CA  1 
ATOM   3882  C  C   . ILE A 1 536 ? 195.427 138.880 137.462 1.00 87.31  ? 529 ILE A C   1 
ATOM   3883  O  O   . ILE A 1 536 ? 194.404 138.186 137.412 1.00 87.31  ? 529 ILE A O   1 
ATOM   3884  C  CB  . ILE A 1 536 ? 195.152 141.188 138.497 1.00 87.31  ? 529 ILE A CB  1 
ATOM   3885  C  CG1 . ILE A 1 536 ? 193.655 141.146 138.191 1.00 87.31  ? 529 ILE A CG1 1 
ATOM   3886  C  CG2 . ILE A 1 536 ? 195.886 141.938 137.406 1.00 87.31  ? 529 ILE A CG2 1 
ATOM   3887  C  CD1 . ILE A 1 536 ? 193.026 142.510 138.101 1.00 87.31  ? 529 ILE A CD1 1 
ATOM   3888  N  N   . LEU A 1 537 ? 196.324 138.879 136.473 1.00 89.56  ? 530 LEU A N   1 
ATOM   3889  C  CA  . LEU A 1 537 ? 196.136 138.007 135.319 1.00 89.56  ? 530 LEU A CA  1 
ATOM   3890  C  C   . LEU A 1 537 ? 196.322 136.534 135.661 1.00 89.56  ? 530 LEU A C   1 
ATOM   3891  O  O   . LEU A 1 537 ? 195.632 135.688 135.083 1.00 89.56  ? 530 LEU A O   1 
ATOM   3892  C  CB  . LEU A 1 537 ? 197.091 138.401 134.193 1.00 89.56  ? 530 LEU A CB  1 
ATOM   3893  C  CG  . LEU A 1 537 ? 196.639 139.585 133.341 1.00 89.56  ? 530 LEU A CG  1 
ATOM   3894  C  CD1 . LEU A 1 537 ? 197.623 139.847 132.216 1.00 89.56  ? 530 LEU A CD1 1 
ATOM   3895  C  CD2 . LEU A 1 537 ? 195.251 139.323 132.789 1.00 89.56  ? 530 LEU A CD2 1 
ATOM   3896  N  N   . SER A 1 538 ? 197.228 136.207 136.580 1.00 90.53  ? 531 SER A N   1 
ATOM   3897  C  CA  . SER A 1 538 ? 197.481 134.821 136.945 1.00 90.53  ? 531 SER A CA  1 
ATOM   3898  C  C   . SER A 1 538 ? 196.608 134.332 138.092 1.00 90.53  ? 531 SER A C   1 
ATOM   3899  O  O   . SER A 1 538 ? 196.676 133.146 138.433 1.00 90.53  ? 531 SER A O   1 
ATOM   3900  C  CB  . SER A 1 538 ? 198.956 134.635 137.314 1.00 90.53  ? 531 SER A CB  1 
ATOM   3901  O  OG  . SER A 1 538 ? 199.709 134.203 136.195 1.00 90.53  ? 531 SER A OG  1 
ATOM   3902  N  N   . ASN A 1 539 ? 195.807 135.206 138.698 1.00 84.53  ? 532 ASN A N   1 
ATOM   3903  C  CA  . ASN A 1 539 ? 194.882 134.765 139.733 1.00 84.53  ? 532 ASN A CA  1 
ATOM   3904  C  C   . ASN A 1 539 ? 193.861 133.795 139.150 1.00 84.53  ? 532 ASN A C   1 
ATOM   3905  O  O   . ASN A 1 539 ? 193.356 133.990 138.041 1.00 84.53  ? 532 ASN A O   1 
ATOM   3906  C  CB  . ASN A 1 539 ? 194.174 135.968 140.359 1.00 84.53  ? 532 ASN A CB  1 
ATOM   3907  C  CG  . ASN A 1 539 ? 193.505 135.632 141.678 1.00 84.53  ? 532 ASN A CG  1 
ATOM   3908  O  OD1 . ASN A 1 539 ? 193.289 134.464 142.000 1.00 84.53  ? 532 ASN A OD1 1 
ATOM   3909  N  ND2 . ASN A 1 539 ? 193.176 136.660 142.451 1.00 84.53  ? 532 ASN A ND2 1 
ATOM   3910  N  N   . LYS A 1 540 ? 193.560 132.742 139.907 1.00 82.69  ? 533 LYS A N   1 
ATOM   3911  C  CA  . LYS A 1 540 ? 192.671 131.675 139.459 1.00 82.69  ? 533 LYS A CA  1 
ATOM   3912  C  C   . LYS A 1 540 ? 191.276 131.769 140.060 1.00 82.69  ? 533 LYS A C   1 
ATOM   3913  O  O   . LYS A 1 540 ? 190.282 131.578 139.347 1.00 82.69  ? 533 LYS A O   1 
ATOM   3914  C  CB  . LYS A 1 540 ? 193.283 130.312 139.797 1.00 82.69  ? 533 LYS A CB  1 
ATOM   3915  C  CG  . LYS A 1 540 ? 192.329 129.138 139.650 1.00 82.69  ? 533 LYS A CG  1 
ATOM   3916  C  CD  . LYS A 1 540 ? 193.067 127.806 139.683 1.00 82.69  ? 533 LYS A CD  1 
ATOM   3917  C  CE  . LYS A 1 540 ? 194.381 127.857 138.913 1.00 82.69  ? 533 LYS A CE  1 
ATOM   3918  N  NZ  . LYS A 1 540 ? 194.198 128.282 137.495 1.00 82.69  ? 533 LYS A NZ  1 
ATOM   3919  N  N   . THR A 1 541 ? 191.178 132.053 141.360 1.00 77.35  ? 534 THR A N   1 
ATOM   3920  C  CA  . THR A 1 541 ? 189.869 132.236 141.976 1.00 77.35  ? 534 THR A CA  1 
ATOM   3921  C  C   . THR A 1 541 ? 189.135 133.415 141.353 1.00 77.35  ? 534 THR A C   1 
ATOM   3922  O  O   . THR A 1 541 ? 187.922 133.350 141.119 1.00 77.35  ? 534 THR A O   1 
ATOM   3923  C  CB  . THR A 1 541 ? 190.020 132.434 143.485 1.00 77.35  ? 534 THR A CB  1 
ATOM   3924  O  OG1 . THR A 1 541 ? 191.000 133.447 143.740 1.00 77.35  ? 534 THR A OG1 1 
ATOM   3925  C  CG2 . THR A 1 541 ? 190.456 131.138 144.150 1.00 77.35  ? 534 THR A CG2 1 
ATOM   3926  N  N   . LEU A 1 542 ? 189.858 134.504 141.078 1.00 73.15  ? 535 LEU A N   1 
ATOM   3927  C  CA  . LEU A 1 542 ? 189.243 135.649 140.416 1.00 73.15  ? 535 LEU A CA  1 
ATOM   3928  C  C   . LEU A 1 542 ? 188.758 135.281 139.021 1.00 73.15  ? 535 LEU A C   1 
ATOM   3929  O  O   . LEU A 1 542 ? 187.679 135.711 138.602 1.00 73.15  ? 535 LEU A O   1 
ATOM   3930  C  CB  . LEU A 1 542 ? 190.226 136.816 140.352 1.00 73.15  ? 535 LEU A CB  1 
ATOM   3931  C  CG  . LEU A 1 542 ? 189.639 138.103 139.773 1.00 73.15  ? 535 LEU A CG  1 
ATOM   3932  C  CD1 . LEU A 1 542 ? 188.712 138.761 140.777 1.00 73.15  ? 535 LEU A CD1 1 
ATOM   3933  C  CD2 . LEU A 1 542 ? 190.741 139.059 139.355 1.00 73.15  ? 535 LEU A CD2 1 
ATOM   3934  N  N   . ARG A 1 543 ? 189.542 134.490 138.286 1.00 76.24  ? 536 ARG A N   1 
ATOM   3935  C  CA  . ARG A 1 543 ? 189.112 134.060 136.959 1.00 76.24  ? 536 ARG A CA  1 
ATOM   3936  C  C   . ARG A 1 543 ? 187.849 133.213 137.035 1.00 76.24  ? 536 ARG A C   1 
ATOM   3937  O  O   . ARG A 1 543 ? 186.935 133.375 136.221 1.00 76.24  ? 536 ARG A O   1 
ATOM   3938  C  CB  . ARG A 1 543 ? 190.234 133.289 136.264 1.00 76.24  ? 536 ARG A CB  1 
ATOM   3939  C  CG  . ARG A 1 543 ? 189.831 132.675 134.933 1.00 76.24  ? 536 ARG A CG  1 
ATOM   3940  C  CD  . ARG A 1 543 ? 191.013 132.560 133.985 1.00 76.24  ? 536 ARG A CD  1 
ATOM   3941  N  NE  . ARG A 1 543 ? 191.043 133.642 133.009 1.00 76.24  ? 536 ARG A NE  1 
ATOM   3942  C  CZ  . ARG A 1 543 ? 191.947 134.612 132.993 1.00 76.24  ? 536 ARG A CZ  1 
ATOM   3943  N  NH1 . ARG A 1 543 ? 192.912 134.673 133.896 1.00 76.24  ? 536 ARG A NH1 1 
ATOM   3944  N  NH2 . ARG A 1 543 ? 191.881 135.544 132.047 1.00 76.24  ? 536 ARG A NH2 1 
ATOM   3945  N  N   . GLU A 1 544 ? 187.779 132.305 138.009 1.00 72.61  ? 537 GLU A N   1 
ATOM   3946  C  CA  . GLU A 1 544 ? 186.586 131.474 138.167 1.00 72.61  ? 537 GLU A CA  1 
ATOM   3947  C  C   . GLU A 1 544 ? 185.364 132.324 138.510 1.00 72.61  ? 537 GLU A C   1 
ATOM   3948  O  O   . GLU A 1 544 ? 184.276 132.147 137.936 1.00 72.61  ? 537 GLU A O   1 
ATOM   3949  C  CB  . GLU A 1 544 ? 186.839 130.419 139.245 1.00 72.61  ? 537 GLU A CB  1 
ATOM   3950  C  CG  . GLU A 1 544 ? 187.912 129.396 138.917 1.00 72.61  ? 537 GLU A CG  1 
ATOM   3951  C  CD  . GLU A 1 544 ? 187.632 128.621 137.643 1.00 72.61  ? 537 GLU A CD  1 
ATOM   3952  O  OE1 . GLU A 1 544 ? 186.462 128.259 137.403 1.00 72.61  ? 537 GLU A OE1 1 
ATOM   3953  O  OE2 . GLU A 1 544 ? 188.588 128.374 136.880 1.00 72.61  ? 537 GLU A OE2 1 
ATOM   3954  N  N   . HIS A 1 545 ? 185.532 133.265 139.441 1.00 65.45  ? 538 HIS A N   1 
ATOM   3955  C  CA  . HIS A 1 545 ? 184.426 134.134 139.827 1.00 65.45  ? 538 HIS A CA  1 
ATOM   3956  C  C   . HIS A 1 545 ? 183.960 134.981 138.651 1.00 65.45  ? 538 HIS A C   1 
ATOM   3957  O  O   . HIS A 1 545 ? 182.753 135.159 138.438 1.00 65.45  ? 538 HIS A O   1 
ATOM   3958  C  CB  . HIS A 1 545 ? 184.847 135.019 140.998 1.00 65.45  ? 538 HIS A CB  1 
ATOM   3959  C  CG  . HIS A 1 545 ? 185.184 134.258 142.242 1.00 65.45  ? 538 HIS A CG  1 
ATOM   3960  N  ND1 . HIS A 1 545 ? 185.543 134.877 143.419 1.00 65.45  ? 538 HIS A ND1 1 
ATOM   3961  C  CD2 . HIS A 1 545 ? 185.210 132.928 142.494 1.00 65.45  ? 538 HIS A CD2 1 
ATOM   3962  C  CE1 . HIS A 1 545 ? 185.780 133.962 144.342 1.00 65.45  ? 538 HIS A CE1 1 
ATOM   3963  N  NE2 . HIS A 1 545 ? 185.585 132.771 143.806 1.00 65.45  ? 538 HIS A NE2 1 
ATOM   3964  N  N   . ASN A 1 546 ? 184.903 135.503 137.867 1.00 63.19  ? 539 ASN A N   1 
ATOM   3965  C  CA  . ASN A 1 546 ? 184.529 136.304 136.712 1.00 63.19  ? 539 ASN A CA  1 
ATOM   3966  C  C   . ASN A 1 546 ? 183.905 135.453 135.616 1.00 63.19  ? 539 ASN A C   1 
ATOM   3967  O  O   . ASN A 1 546 ? 183.075 135.952 134.857 1.00 63.19  ? 539 ASN A O   1 
ATOM   3968  C  CB  . ASN A 1 546 ? 185.740 137.065 136.185 1.00 63.19  ? 539 ASN A CB  1 
ATOM   3969  C  CG  . ASN A 1 546 ? 185.974 138.356 136.932 1.00 63.19  ? 539 ASN A CG  1 
ATOM   3970  O  OD1 . ASN A 1 546 ? 185.452 139.405 136.559 1.00 63.19  ? 539 ASN A OD1 1 
ATOM   3971  N  ND2 . ASN A 1 546 ? 186.749 138.286 138.006 1.00 63.19  ? 539 ASN A ND2 1 
ATOM   3972  N  N   . SER A 1 547 ? 184.269 134.173 135.524 1.00 60.69  ? 540 SER A N   1 
ATOM   3973  C  CA  . SER A 1 547 ? 183.575 133.286 134.596 1.00 60.69  ? 540 SER A CA  1 
ATOM   3974  C  C   . SER A 1 547 ? 182.116 133.109 134.998 1.00 60.69  ? 540 SER A C   1 
ATOM   3975  O  O   . SER A 1 547 ? 181.218 133.145 134.147 1.00 60.69  ? 540 SER A O   1 
ATOM   3976  C  CB  . SER A 1 547 ? 184.281 131.933 134.532 1.00 60.69  ? 540 SER A CB  1 
ATOM   3977  O  OG  . SER A 1 547 ? 183.536 131.010 133.759 1.00 60.69  ? 540 SER A OG  1 
ATOM   3978  N  N   . PHE A 1 548 ? 181.860 132.923 136.294 1.00 56.99  ? 541 PHE A N   1 
ATOM   3979  C  CA  . PHE A 1 548 ? 180.475 132.831 136.759 1.00 56.99  ? 541 PHE A CA  1 
ATOM   3980  C  C   . PHE A 1 548 ? 179.712 134.124 136.475 1.00 56.99  ? 541 PHE A C   1 
ATOM   3981  O  O   . PHE A 1 548 ? 178.561 134.103 136.007 1.00 56.99  ? 541 PHE A O   1 
ATOM   3982  C  CB  . PHE A 1 548 ? 180.445 132.510 138.252 1.00 56.99  ? 541 PHE A CB  1 
ATOM   3983  C  CG  . PHE A 1 548 ? 179.088 132.652 138.875 1.00 56.99  ? 541 PHE A CG  1 
ATOM   3984  C  CD1 . PHE A 1 548 ? 177.990 132.010 138.333 1.00 56.99  ? 541 PHE A CD1 1 
ATOM   3985  C  CD2 . PHE A 1 548 ? 178.909 133.436 140.001 1.00 56.99  ? 541 PHE A CD2 1 
ATOM   3986  C  CE1 . PHE A 1 548 ? 176.742 132.143 138.904 1.00 56.99  ? 541 PHE A CE1 1 
ATOM   3987  C  CE2 . PHE A 1 548 ? 177.662 133.574 140.576 1.00 56.99  ? 541 PHE A CE2 1 
ATOM   3988  C  CZ  . PHE A 1 548 ? 176.578 132.927 140.026 1.00 56.99  ? 541 PHE A CZ  1 
ATOM   3989  N  N   . VAL A 1 549 ? 180.345 135.263 136.758 1.00 54.46  ? 542 VAL A N   1 
ATOM   3990  C  CA  . VAL A 1 549 ? 179.702 136.552 136.523 1.00 54.46  ? 542 VAL A CA  1 
ATOM   3991  C  C   . VAL A 1 549 ? 179.433 136.748 135.035 1.00 54.46  ? 542 VAL A C   1 
ATOM   3992  O  O   . VAL A 1 549 ? 178.390 137.284 134.640 1.00 54.46  ? 542 VAL A O   1 
ATOM   3993  C  CB  . VAL A 1 549 ? 180.566 137.681 137.112 1.00 54.46  ? 542 VAL A CB  1 
ATOM   3994  C  CG1 . VAL A 1 549 ? 180.324 138.990 136.386 1.00 54.46  ? 542 VAL A CG1 1 
ATOM   3995  C  CG2 . VAL A 1 549 ? 180.292 137.821 138.598 1.00 54.46  ? 542 VAL A CG2 1 
ATOM   3996  N  N   . GLU A 1 550 ? 180.360 136.297 134.188 1.00 55.33  ? 543 GLU A N   1 
ATOM   3997  C  CA  . GLU A 1 550 ? 180.168 136.378 132.746 1.00 55.33  ? 543 GLU A CA  1 
ATOM   3998  C  C   . GLU A 1 550 ? 179.002 135.512 132.297 1.00 55.33  ? 543 GLU A C   1 
ATOM   3999  O  O   . GLU A 1 550 ? 178.253 135.892 131.394 1.00 55.33  ? 543 GLU A O   1 
ATOM   4000  C  CB  . GLU A 1 550 ? 181.450 135.962 132.027 1.00 55.33  ? 543 GLU A CB  1 
ATOM   4001  C  CG  . GLU A 1 550 ? 181.281 135.741 130.538 1.00 55.33  ? 543 GLU A CG  1 
ATOM   4002  C  CD  . GLU A 1 550 ? 181.317 134.274 130.163 1.00 55.33  ? 543 GLU A CD  1 
ATOM   4003  O  OE1 . GLU A 1 550 ? 181.097 133.427 131.053 1.00 55.33  ? 543 GLU A OE1 1 
ATOM   4004  O  OE2 . GLU A 1 550 ? 181.567 133.966 128.979 1.00 55.33  ? 543 GLU A OE2 1 
ATOM   4005  N  N   . ARG A 1 551 ? 178.842 134.334 132.902 1.00 55.34  ? 544 ARG A N   1 
ATOM   4006  C  CA  . ARG A 1 551 ? 177.700 133.488 132.560 1.00 55.34  ? 544 ARG A CA  1 
ATOM   4007  C  C   . ARG A 1 551 ? 176.382 134.173 132.910 1.00 55.34  ? 544 ARG A C   1 
ATOM   4008  O  O   . ARG A 1 551 ? 175.430 134.160 132.115 1.00 55.34  ? 544 ARG A O   1 
ATOM   4009  C  CB  . ARG A 1 551 ? 177.819 132.143 133.272 1.00 55.34  ? 544 ARG A CB  1 
ATOM   4010  C  CG  . ARG A 1 551 ? 176.928 131.059 132.706 1.00 55.34  ? 544 ARG A CG  1 
ATOM   4011  C  CD  . ARG A 1 551 ? 177.687 129.747 132.608 1.00 55.34  ? 544 ARG A CD  1 
ATOM   4012  N  NE  . ARG A 1 551 ? 177.964 129.180 133.922 1.00 55.34  ? 544 ARG A NE  1 
ATOM   4013  C  CZ  . ARG A 1 551 ? 178.946 128.327 134.179 1.00 55.34  ? 544 ARG A CZ  1 
ATOM   4014  N  NH1 . ARG A 1 551 ? 179.774 127.922 133.231 1.00 55.34  ? 544 ARG A NH1 1 
ATOM   4015  N  NH2 . ARG A 1 551 ? 179.101 127.872 135.419 1.00 55.34  ? 544 ARG A NH2 1 
ATOM   4016  N  N   . CYS A 1 552 ? 176.314 134.788 134.095 1.00 50.07  ? 545 CYS A N   1 
ATOM   4017  C  CA  . CYS A 1 552 ? 175.103 135.522 134.465 1.00 50.07  ? 545 CYS A CA  1 
ATOM   4018  C  C   . CYS A 1 552 ? 174.842 136.681 133.507 1.00 50.07  ? 545 CYS A C   1 
ATOM   4019  O  O   . CYS A 1 552 ? 173.698 136.913 133.085 1.00 50.07  ? 545 CYS A O   1 
ATOM   4020  C  CB  . CYS A 1 552 ? 175.211 136.032 135.900 1.00 50.07  ? 545 CYS A CB  1 
ATOM   4021  S  SG  . CYS A 1 552 ? 175.402 134.743 137.143 1.00 50.07  ? 545 CYS A SG  1 
ATOM   4022  N  N   . ILE A 1 553 ? 175.897 137.417 133.150 1.00 47.75  ? 546 ILE A N   1 
ATOM   4023  C  CA  . ILE A 1 553 ? 175.750 138.543 132.233 1.00 47.75  ? 546 ILE A CA  1 
ATOM   4024  C  C   . ILE A 1 553 ? 175.288 138.060 130.865 1.00 47.75  ? 546 ILE A C   1 
ATOM   4025  O  O   . ILE A 1 553 ? 174.483 138.719 130.201 1.00 47.75  ? 546 ILE A O   1 
ATOM   4026  C  CB  . ILE A 1 553 ? 177.072 139.328 132.140 1.00 47.75  ? 546 ILE A CB  1 
ATOM   4027  C  CG1 . ILE A 1 553 ? 177.277 140.184 133.391 1.00 47.75  ? 546 ILE A CG1 1 
ATOM   4028  C  CG2 . ILE A 1 553 ? 177.096 140.192 130.891 1.00 47.75  ? 546 ILE A CG2 1 
ATOM   4029  C  CD1 . ILE A 1 553 ? 176.496 141.466 133.383 1.00 47.75  ? 546 ILE A CD1 1 
ATOM   4030  N  N   . ASP A 1 554 ? 175.792 136.907 130.420 1.00 49.77  ? 547 ASP A N   1 
ATOM   4031  C  CA  . ASP A 1 554 ? 175.381 136.360 129.132 1.00 49.77  ? 547 ASP A CA  1 
ATOM   4032  C  C   . ASP A 1 554 ? 173.907 135.986 129.139 1.00 49.77  ? 547 ASP A C   1 
ATOM   4033  O  O   . ASP A 1 554 ? 173.185 136.249 128.167 1.00 49.77  ? 547 ASP A O   1 
ATOM   4034  C  CB  . ASP A 1 554 ? 176.236 135.142 128.787 1.00 49.77  ? 547 ASP A CB  1 
ATOM   4035  C  CG  . ASP A 1 554 ? 177.145 135.386 127.603 1.00 49.77  ? 547 ASP A CG  1 
ATOM   4036  O  OD1 . ASP A 1 554 ? 177.323 136.561 127.223 1.00 49.77  ? 547 ASP A OD1 1 
ATOM   4037  O  OD2 . ASP A 1 554 ? 177.681 134.402 127.052 1.00 49.77  ? 547 ASP A OD2 1 
ATOM   4038  N  N   . TRP A 1 555 ? 173.442 135.363 130.224 1.00 44.52  ? 548 TRP A N   1 
ATOM   4039  C  CA  . TRP A 1 555 ? 172.022 135.037 130.318 1.00 44.52  ? 548 TRP A CA  1 
ATOM   4040  C  C   . TRP A 1 555 ? 171.172 136.302 130.266 1.00 44.52  ? 548 TRP A C   1 
ATOM   4041  O  O   . TRP A 1 555 ? 170.161 136.360 129.552 1.00 44.52  ? 548 TRP A O   1 
ATOM   4042  C  CB  . TRP A 1 555 ? 171.739 134.253 131.598 1.00 44.52  ? 548 TRP A CB  1 
ATOM   4043  C  CG  . TRP A 1 555 ? 170.284 133.962 131.798 1.00 44.52  ? 548 TRP A CG  1 
ATOM   4044  C  CD1 . TRP A 1 555 ? 169.433 134.599 132.650 1.00 44.52  ? 548 TRP A CD1 1 
ATOM   4045  C  CD2 . TRP A 1 555 ? 169.511 132.955 131.138 1.00 44.52  ? 548 TRP A CD2 1 
ATOM   4046  N  NE1 . TRP A 1 555 ? 168.175 134.056 132.557 1.00 44.52  ? 548 TRP A NE1 1 
ATOM   4047  C  CE2 . TRP A 1 555 ? 168.198 133.043 131.636 1.00 44.52  ? 548 TRP A CE2 1 
ATOM   4048  C  CE3 . TRP A 1 555 ? 169.802 131.989 130.172 1.00 44.52  ? 548 TRP A CE3 1 
ATOM   4049  C  CZ2 . TRP A 1 555 ? 167.178 132.203 131.203 1.00 44.52  ? 548 TRP A CZ2 1 
ATOM   4050  C  CZ3 . TRP A 1 555 ? 168.789 131.157 129.742 1.00 44.52  ? 548 TRP A CZ3 1 
ATOM   4051  C  CH2 . TRP A 1 555 ? 167.493 131.269 130.258 1.00 44.52  ? 548 TRP A CH2 1 
ATOM   4052  N  N   . ASN A 1 556 ? 171.579 137.337 131.006 1.00 43.98  ? 549 ASN A N   1 
ATOM   4053  C  CA  . ASN A 1 556 ? 170.814 138.582 130.984 1.00 43.98  ? 549 ASN A CA  1 
ATOM   4054  C  C   . ASN A 1 556 ? 170.861 139.253 129.616 1.00 43.98  ? 549 ASN A C   1 
ATOM   4055  O  O   . ASN A 1 556 ? 169.869 139.852 129.187 1.00 43.98  ? 549 ASN A O   1 
ATOM   4056  C  CB  . ASN A 1 556 ? 171.321 139.534 132.062 1.00 43.98  ? 549 ASN A CB  1 
ATOM   4057  C  CG  . ASN A 1 556 ? 170.840 139.147 133.439 1.00 43.98  ? 549 ASN A CG  1 
ATOM   4058  O  OD1 . ASN A 1 556 ? 169.918 139.755 133.980 1.00 43.98  ? 549 ASN A OD1 1 
ATOM   4059  N  ND2 . ASN A 1 556 ? 171.457 138.124 134.013 1.00 43.98  ? 549 ASN A ND2 1 
ATOM   4060  N  N   . ARG A 1 557 ? 171.998 139.169 128.924 1.00 46.00  ? 550 ARG A N   1 
ATOM   4061  C  CA  . ARG A 1 557 ? 172.101 139.736 127.584 1.00 46.00  ? 550 ARG A CA  1 
ATOM   4062  C  C   . ARG A 1 557 ? 171.164 139.032 126.618 1.00 46.00  ? 550 ARG A C   1 
ATOM   4063  O  O   . ARG A 1 557 ? 170.514 139.680 125.793 1.00 46.00  ? 550 ARG A O   1 
ATOM   4064  C  CB  . ARG A 1 557 ? 173.541 139.648 127.082 1.00 46.00  ? 550 ARG A CB  1 
ATOM   4065  C  CG  . ARG A 1 557 ? 173.738 140.179 125.675 1.00 46.00  ? 550 ARG A CG  1 
ATOM   4066  C  CD  . ARG A 1 557 ? 174.747 139.336 124.918 1.00 46.00  ? 550 ARG A CD  1 
ATOM   4067  N  NE  . ARG A 1 557 ? 175.493 140.110 123.934 1.00 46.00  ? 550 ARG A NE  1 
ATOM   4068  C  CZ  . ARG A 1 557 ? 176.513 140.905 124.222 1.00 46.00  ? 550 ARG A CZ  1 
ATOM   4069  N  NH1 . ARG A 1 557 ? 176.932 141.070 125.466 1.00 46.00  ? 550 ARG A NH1 1 
ATOM   4070  N  NH2 . ARG A 1 557 ? 177.131 141.550 123.237 1.00 46.00  ? 550 ARG A NH2 1 
ATOM   4071  N  N   . GLU A 1 558 ? 171.090 137.701 126.696 1.00 45.55  ? 551 GLU A N   1 
ATOM   4072  C  CA  . GLU A 1 558 ? 170.153 136.976 125.842 1.00 45.55  ? 551 GLU A CA  1 
ATOM   4073  C  C   . GLU A 1 558 ? 168.714 137.344 126.171 1.00 45.55  ? 551 GLU A C   1 
ATOM   4074  O  O   . GLU A 1 558 ? 167.884 137.502 125.267 1.00 45.55  ? 551 GLU A O   1 
ATOM   4075  C  CB  . GLU A 1 558 ? 170.367 135.471 125.974 1.00 45.55  ? 551 GLU A CB  1 
ATOM   4076  C  CG  . GLU A 1 558 ? 171.695 134.995 125.428 1.00 45.55  ? 551 GLU A CG  1 
ATOM   4077  C  CD  . GLU A 1 558 ? 171.564 134.411 124.039 1.00 45.55  ? 551 GLU A CD  1 
ATOM   4078  O  OE1 . GLU A 1 558 ? 172.387 133.549 123.675 1.00 45.55  ? 551 GLU A OE1 1 
ATOM   4079  O  OE2 . GLU A 1 558 ? 170.634 134.814 123.310 1.00 45.55  ? 551 GLU A OE2 1 
ATOM   4080  N  N   . LEU A 1 559 ? 168.401 137.495 127.459 1.00 41.65  ? 552 LEU A N   1 
ATOM   4081  C  CA  . LEU A 1 559 ? 167.051 137.896 127.845 1.00 41.65  ? 552 LEU A CA  1 
ATOM   4082  C  C   . LEU A 1 559 ? 166.698 139.263 127.269 1.00 41.65  ? 552 LEU A C   1 
ATOM   4083  O  O   . LEU A 1 559 ? 165.614 139.454 126.702 1.00 41.65  ? 552 LEU A O   1 
ATOM   4084  C  CB  . LEU A 1 559 ? 166.927 137.898 129.368 1.00 41.65  ? 552 LEU A CB  1 
ATOM   4085  C  CG  . LEU A 1 559 ? 165.527 138.022 129.965 1.00 41.65  ? 552 LEU A CG  1 
ATOM   4086  C  CD1 . LEU A 1 559 ? 164.506 137.294 129.113 1.00 41.65  ? 552 LEU A CD1 1 
ATOM   4087  C  CD2 . LEU A 1 559 ? 165.524 137.480 131.380 1.00 41.65  ? 552 LEU A CD2 1 
ATOM   4088  N  N   . LEU A 1 560 ? 167.614 140.227 127.391 1.00 39.75  ? 553 LEU A N   1 
ATOM   4089  C  CA  . LEU A 1 560 ? 167.359 141.564 126.863 1.00 39.75  ? 553 LEU A CA  1 
ATOM   4090  C  C   . LEU A 1 560 ? 167.266 141.557 125.343 1.00 39.75  ? 553 LEU A C   1 
ATOM   4091  O  O   . LEU A 1 560 ? 166.434 142.263 124.766 1.00 39.75  ? 553 LEU A O   1 
ATOM   4092  C  CB  . LEU A 1 560 ? 168.445 142.532 127.325 1.00 39.75  ? 553 LEU A CB  1 
ATOM   4093  C  CG  . LEU A 1 560 ? 168.315 143.046 128.756 1.00 39.75  ? 553 LEU A CG  1 
ATOM   4094  C  CD1 . LEU A 1 560 ? 169.604 143.710 129.197 1.00 39.75  ? 553 LEU A CD1 1 
ATOM   4095  C  CD2 . LEU A 1 560 ? 167.153 144.010 128.857 1.00 39.75  ? 553 LEU A CD2 1 
ATOM   4096  N  N   . LYS A 1 561 ? 168.118 140.776 124.676 1.00 39.70  ? 554 LYS A N   1 
ATOM   4097  C  CA  . LYS A 1 561 ? 168.069 140.698 123.222 1.00 39.70  ? 554 LYS A CA  1 
ATOM   4098  C  C   . LYS A 1 561 ? 166.757 140.094 122.745 1.00 39.70  ? 554 LYS A C   1 
ATOM   4099  O  O   . LYS A 1 561 ? 166.224 140.504 121.709 1.00 39.70  ? 554 LYS A O   1 
ATOM   4100  C  CB  . LYS A 1 561 ? 169.259 139.886 122.712 1.00 39.70  ? 554 LYS A CB  1 
ATOM   4101  C  CG  . LYS A 1 561 ? 169.178 139.470 121.260 1.00 39.70  ? 554 LYS A CG  1 
ATOM   4102  C  CD  . LYS A 1 561 ? 170.565 139.404 120.644 1.00 39.70  ? 554 LYS A CD  1 
ATOM   4103  C  CE  . LYS A 1 561 ? 171.351 138.224 121.185 1.00 39.70  ? 554 LYS A CE  1 
ATOM   4104  N  NZ  . LYS A 1 561 ? 172.624 138.021 120.443 1.00 39.70  ? 554 LYS A NZ  1 
ATOM   4105  N  N   . ARG A 1 562 ? 166.218 139.129 123.490 1.00 41.99  ? 555 ARG A N   1 
ATOM   4106  C  CA  . ARG A 1 562 ? 164.925 138.560 123.130 1.00 41.99  ? 555 ARG A CA  1 
ATOM   4107  C  C   . ARG A 1 562 ? 163.790 139.545 123.391 1.00 41.99  ? 555 ARG A C   1 
ATOM   4108  O  O   . ARG A 1 562 ? 162.849 139.637 122.596 1.00 41.99  ? 555 ARG A O   1 
ATOM   4109  C  CB  . ARG A 1 562 ? 164.695 137.261 123.901 1.00 41.99  ? 555 ARG A CB  1 
ATOM   4110  C  CG  . ARG A 1 562 ? 163.346 136.608 123.648 1.00 41.99  ? 555 ARG A CG  1 
ATOM   4111  C  CD  . ARG A 1 562 ? 163.377 135.133 124.013 1.00 41.99  ? 555 ARG A CD  1 
ATOM   4112  N  NE  . ARG A 1 562 ? 162.914 134.902 125.376 1.00 41.99  ? 555 ARG A NE  1 
ATOM   4113  C  CZ  . ARG A 1 562 ? 163.638 134.327 126.327 1.00 41.99  ? 555 ARG A CZ  1 
ATOM   4114  N  NH1 . ARG A 1 562 ? 164.873 133.911 126.100 1.00 41.99  ? 555 ARG A NH1 1 
ATOM   4115  N  NH2 . ARG A 1 562 ? 163.109 134.166 127.537 1.00 41.99  ? 555 ARG A NH2 1 
ATOM   4116  N  N   . GLU A 1 563 ? 163.861 140.293 124.494 1.00 40.71  ? 556 GLU A N   1 
ATOM   4117  C  CA  . GLU A 1 563 ? 162.729 141.107 124.924 1.00 40.71  ? 556 GLU A CA  1 
ATOM   4118  C  C   . GLU A 1 563 ? 162.728 142.526 124.364 1.00 40.71  ? 556 GLU A C   1 
ATOM   4119  O  O   . GLU A 1 563 ? 161.703 143.207 124.470 1.00 40.71  ? 556 GLU A O   1 
ATOM   4120  C  CB  . GLU A 1 563 ? 162.682 141.171 126.453 1.00 40.71  ? 556 GLU A CB  1 
ATOM   4121  C  CG  . GLU A 1 563 ? 162.438 139.827 127.121 1.00 40.71  ? 556 GLU A CG  1 
ATOM   4122  C  CD  . GLU A 1 563 ? 160.974 139.436 127.144 1.00 40.71  ? 556 GLU A CD  1 
ATOM   4123  O  OE1 . GLU A 1 563 ? 160.385 139.251 126.058 1.00 40.71  ? 556 GLU A OE1 1 
ATOM   4124  O  OE2 . GLU A 1 563 ? 160.412 139.306 128.251 1.00 40.71  ? 556 GLU A OE2 1 
ATOM   4125  N  N   . LEU A 1 564 ? 163.830 142.996 123.778 1.00 38.03  ? 557 LEU A N   1 
ATOM   4126  C  CA  . LEU A 1 564 ? 163.889 144.351 123.240 1.00 38.03  ? 557 LEU A CA  1 
ATOM   4127  C  C   . LEU A 1 564 ? 164.252 144.390 121.762 1.00 38.03  ? 557 LEU A C   1 
ATOM   4128  O  O   . LEU A 1 564 ? 164.564 145.468 121.243 1.00 38.03  ? 557 LEU A O   1 
ATOM   4129  C  CB  . LEU A 1 564 ? 164.881 145.202 124.039 1.00 38.03  ? 557 LEU A CB  1 
ATOM   4130  C  CG  . LEU A 1 564 ? 164.497 145.511 125.485 1.00 38.03  ? 557 LEU A CG  1 
ATOM   4131  C  CD1 . LEU A 1 564 ? 165.502 146.459 126.111 1.00 38.03  ? 557 LEU A CD1 1 
ATOM   4132  C  CD2 . LEU A 1 564 ? 163.097 146.089 125.554 1.00 38.03  ? 557 LEU A CD2 1 
ATOM   4133  N  N   . GLY A 1 565 ? 164.221 143.254 121.073 1.00 38.71  ? 558 GLY A N   1 
ATOM   4134  C  CA  . GLY A 1 565 ? 164.460 143.242 119.638 1.00 38.71  ? 558 GLY A CA  1 
ATOM   4135  C  C   . GLY A 1 565 ? 165.810 143.789 119.233 1.00 38.71  ? 558 GLY A C   1 
ATOM   4136  O  O   . GLY A 1 565 ? 165.914 144.498 118.225 1.00 38.71  ? 558 GLY A O   1 
ATOM   4137  N  N   . LEU A 1 566 ? 166.849 143.479 119.998 1.00 39.42  ? 559 LEU A N   1 
ATOM   4138  C  CA  . LEU A 1 566 ? 168.185 143.983 119.724 1.00 39.42  ? 559 LEU A CA  1 
ATOM   4139  C  C   . LEU A 1 566 ? 168.976 142.998 118.878 1.00 39.42  ? 559 LEU A C   1 
ATOM   4140  O  O   . LEU A 1 566 ? 168.757 141.786 118.927 1.00 39.42  ? 559 LEU A O   1 
ATOM   4141  C  CB  . LEU A 1 566 ? 168.939 144.252 121.027 1.00 39.42  ? 559 LEU A CB  1 
ATOM   4142  C  CG  . LEU A 1 566 ? 168.428 145.375 121.925 1.00 39.42  ? 559 LEU A CG  1 
ATOM   4143  C  CD1 . LEU A 1 566 ? 169.260 145.439 123.184 1.00 39.42  ? 559 LEU A CD1 1 
ATOM   4144  C  CD2 . LEU A 1 566 ? 168.474 146.700 121.192 1.00 39.42  ? 559 LEU A CD2 1 
ATOM   4145  N  N   . ALA A 1 567 ? 169.897 143.536 118.093 1.00 42.23  ? 560 ALA A N   1 
ATOM   4146  C  CA  . ALA A 1 567 ? 170.906 142.749 117.413 1.00 42.23  ? 560 ALA A CA  1 
ATOM   4147  C  C   . ALA A 1 567 ? 172.214 142.871 118.188 1.00 42.23  ? 560 ALA A C   1 
ATOM   4148  O  O   . ALA A 1 567 ? 172.264 143.459 119.271 1.00 42.23  ? 560 ALA A O   1 
ATOM   4149  C  CB  . ALA A 1 567 ? 171.047 143.205 115.961 1.00 42.23  ? 560 ALA A CB  1 
ATOM   4150  N  N   . GLU A 1 568 ? 173.290 142.312 117.641 1.00 46.24  ? 561 GLU A N   1 
ATOM   4151  C  CA  . GLU A 1 568 ? 174.588 142.460 118.282 1.00 46.24  ? 561 GLU A CA  1 
ATOM   4152  C  C   . GLU A 1 568 ? 175.215 143.826 118.039 1.00 46.24  ? 561 GLU A C   1 
ATOM   4153  O  O   . GLU A 1 568 ? 176.224 144.146 118.675 1.00 46.24  ? 561 GLU A O   1 
ATOM   4154  C  CB  . GLU A 1 568 ? 175.543 141.364 117.807 1.00 46.24  ? 561 GLU A CB  1 
ATOM   4155  C  CG  . GLU A 1 568 ? 175.775 140.268 118.832 1.00 46.24  ? 561 GLU A CG  1 
ATOM   4156  C  CD  . GLU A 1 568 ? 176.461 140.780 120.085 1.00 46.24  ? 561 GLU A CD  1 
ATOM   4157  O  OE1 . GLU A 1 568 ? 177.565 141.351 119.969 1.00 46.24  ? 561 GLU A OE1 1 
ATOM   4158  O  OE2 . GLU A 1 568 ? 175.897 140.609 121.186 1.00 46.24  ? 561 GLU A OE2 1 
ATOM   4159  N  N   . SER A 1 569 ? 174.649 144.632 117.144 1.00 44.89  ? 562 SER A N   1 
ATOM   4160  C  CA  . SER A 1 569 ? 175.187 145.951 116.844 1.00 44.89  ? 562 SER A CA  1 
ATOM   4161  C  C   . SER A 1 569 ? 174.703 147.031 117.801 1.00 44.89  ? 562 SER A C   1 
ATOM   4162  O  O   . SER A 1 569 ? 175.266 148.131 117.800 1.00 44.89  ? 562 SER A O   1 
ATOM   4163  C  CB  . SER A 1 569 ? 174.828 146.352 115.410 1.00 44.89  ? 562 SER A CB  1 
ATOM   4164  O  OG  . SER A 1 569 ? 175.301 145.394 114.479 1.00 44.89  ? 562 SER A OG  1 
ATOM   4165  N  N   . ASP A 1 570 ? 173.684 146.752 118.613 1.00 42.48  ? 563 ASP A N   1 
ATOM   4166  C  CA  . ASP A 1 570 ? 173.122 147.730 119.534 1.00 42.48  ? 563 ASP A CA  1 
ATOM   4167  C  C   . ASP A 1 570 ? 173.608 147.549 120.964 1.00 42.48  ? 563 ASP A C   1 
ATOM   4168  O  O   . ASP A 1 570 ? 173.112 148.230 121.865 1.00 42.48  ? 563 ASP A O   1 
ATOM   4169  C  CB  . ASP A 1 570 ? 171.594 147.672 119.503 1.00 42.48  ? 563 ASP A CB  1 
ATOM   4170  C  CG  . ASP A 1 570 ? 171.023 148.099 118.171 1.00 42.48  ? 563 ASP A CG  1 
ATOM   4171  O  OD1 . ASP A 1 570 ? 171.276 149.248 117.758 1.00 42.48  ? 563 ASP A OD1 1 
ATOM   4172  O  OD2 . ASP A 1 570 ? 170.319 147.288 117.536 1.00 42.48  ? 563 ASP A OD2 1 
ATOM   4173  N  N   . ILE A 1 571 ? 174.560 146.651 121.198 1.00 41.56  ? 564 ILE A N   1 
ATOM   4174  C  CA  . ILE A 1 571 ? 175.046 146.355 122.539 1.00 41.56  ? 564 ILE A CA  1 
ATOM   4175  C  C   . ILE A 1 571 ? 176.548 146.595 122.572 1.00 41.56  ? 564 ILE A C   1 
ATOM   4176  O  O   . ILE A 1 571 ? 177.282 146.088 121.717 1.00 41.56  ? 564 ILE A O   1 
ATOM   4177  C  CB  . ILE A 1 571 ? 174.703 144.916 122.960 1.00 41.56  ? 564 ILE A CB  1 
ATOM   4178  C  CG1 . ILE A 1 571 ? 173.263 144.847 123.466 1.00 41.56  ? 564 ILE A CG1 1 
ATOM   4179  C  CG2 . ILE A 1 571 ? 175.647 144.435 124.041 1.00 41.56  ? 564 ILE A CG2 1 
ATOM   4180  C  CD1 . ILE A 1 571 ? 172.711 143.449 123.542 1.00 41.56  ? 564 ILE A CD1 1 
ATOM   4181  N  N   . ILE A 1 572 ? 176.964 147.398 123.559 1.00 46.87  ? 565 ILE A N   1 
ATOM   4182  C  CA  . ILE A 1 572 ? 178.403 147.745 123.723 1.00 46.87  ? 565 ILE A CA  1 
ATOM   4183  C  C   . ILE A 1 572 ? 178.881 147.178 125.061 1.00 46.87  ? 565 ILE A C   1 
ATOM   4184  O  O   . ILE A 1 572 ? 178.153 147.330 126.059 1.00 46.87  ? 565 ILE A O   1 
ATOM   4185  C  CB  . ILE A 1 572 ? 178.583 149.275 123.665 1.00 46.87  ? 565 ILE A CB  1 
ATOM   4186  C  CG1 . ILE A 1 572 ? 178.000 149.868 122.379 1.00 46.87  ? 565 ILE A CG1 1 
ATOM   4187  C  CG2 . ILE A 1 572 ? 180.042 149.657 123.854 1.00 46.87  ? 565 ILE A CG2 1 
ATOM   4188  C  CD1 . ILE A 1 572 ? 178.090 151.374 122.304 1.00 46.87  ? 565 ILE A CD1 1 
ATOM   4189  N  N   . ASP A 1 573 ? 180.054 146.548 125.075 1.00 53.85  ? 566 ASP A N   1 
ATOM   4190  C  CA  . ASP A 1 573 ? 180.624 145.976 126.286 1.00 53.85  ? 566 ASP A CA  1 
ATOM   4191  C  C   . ASP A 1 573 ? 181.627 146.946 126.897 1.00 53.85  ? 566 ASP A C   1 
ATOM   4192  O  O   . ASP A 1 573 ? 182.547 147.407 126.215 1.00 53.85  ? 566 ASP A O   1 
ATOM   4193  C  CB  . ASP A 1 573 ? 181.302 144.640 125.979 1.00 53.85  ? 566 ASP A CB  1 
ATOM   4194  C  CG  . ASP A 1 573 ? 180.316 143.569 125.557 1.00 53.85  ? 566 ASP A CG  1 
ATOM   4195  O  OD1 . ASP A 1 573 ? 179.388 143.271 126.336 1.00 53.85  ? 566 ASP A OD1 1 
ATOM   4196  O  OD2 . ASP A 1 573 ? 180.470 143.024 124.444 1.00 53.85  ? 566 ASP A OD2 1 
ATOM   4197  N  N   . ILE A 1 574 ? 181.419 147.261 128.179 1.00 52.79  ? 567 ILE A N   1 
ATOM   4198  C  CA  . ILE A 1 574 ? 182.378 148.138 128.911 1.00 52.79  ? 567 ILE A CA  1 
ATOM   4199  C  C   . ILE A 1 574 ? 183.108 147.253 129.925 1.00 52.79  ? 567 ILE A C   1 
ATOM   4200  O  O   . ILE A 1 574 ? 182.427 146.618 130.754 1.00 52.79  ? 567 ILE A O   1 
ATOM   4201  C  CB  . ILE A 1 574 ? 181.651 149.325 129.572 1.00 52.79  ? 567 ILE A CB  1 
ATOM   4202  C  CG1 . ILE A 1 574 ? 180.870 150.152 128.547 1.00 52.79  ? 567 ILE A CG1 1 
ATOM   4203  C  CG2 . ILE A 1 574 ? 182.632 150.188 130.351 1.00 52.79  ? 567 ILE A CG2 1 
ATOM   4204  C  CD1 . ILE A 1 574 ? 181.728 150.724 127.446 1.00 52.79  ? 567 ILE A CD1 1 
ATOM   4205  N  N   . PRO A 1 575 ? 184.455 147.174 129.891 1.00 59.52  ? 568 PRO A N   1 
ATOM   4206  C  CA  . PRO A 1 575 ? 185.207 146.270 130.769 1.00 59.52  ? 568 PRO A CA  1 
ATOM   4207  C  C   . PRO A 1 575 ? 184.924 146.532 132.241 1.00 59.52  ? 568 PRO A C   1 
ATOM   4208  O  O   . PRO A 1 575 ? 184.727 147.672 132.665 1.00 59.52  ? 568 PRO A O   1 
ATOM   4209  C  CB  . PRO A 1 575 ? 186.667 146.570 130.414 1.00 59.52  ? 568 PRO A CB  1 
ATOM   4210  C  CG  . PRO A 1 575 ? 186.640 147.898 129.735 1.00 59.52  ? 568 PRO A CG  1 
ATOM   4211  C  CD  . PRO A 1 575 ? 185.336 147.975 129.029 1.00 59.52  ? 568 PRO A CD  1 
ATOM   4212  N  N   . GLN A 1 576 ? 184.901 145.451 133.019 1.00 57.30  ? 569 GLN A N   1 
ATOM   4213  C  CA  . GLN A 1 576 ? 184.670 145.510 134.455 1.00 57.30  ? 569 GLN A CA  1 
ATOM   4214  C  C   . GLN A 1 576 ? 185.133 144.194 135.062 1.00 57.30  ? 569 GLN A C   1 
ATOM   4215  O  O   . GLN A 1 576 ? 185.277 143.195 134.357 1.00 57.30  ? 569 GLN A O   1 
ATOM   4216  C  CB  . GLN A 1 576 ? 183.193 145.765 134.777 1.00 57.30  ? 569 GLN A CB  1 
ATOM   4217  C  CG  . GLN A 1 576 ? 182.935 146.221 136.199 1.00 57.30  ? 569 GLN A CG  1 
ATOM   4218  C  CD  . GLN A 1 576 ? 183.099 147.715 136.365 1.00 57.30  ? 569 GLN A CD  1 
ATOM   4219  O  OE1 . GLN A 1 576 ? 182.393 148.500 135.735 1.00 57.30  ? 569 GLN A OE1 1 
ATOM   4220  N  NE2 . GLN A 1 576 ? 184.036 148.118 137.215 1.00 57.30  ? 569 GLN A NE2 1 
ATOM   4221  N  N   . LEU A 1 577 ? 185.376 144.201 136.369 1.00 57.38  ? 570 LEU A N   1 
ATOM   4222  C  CA  . LEU A 1 577 ? 185.822 143.007 137.073 1.00 57.38  ? 570 LEU A CA  1 
ATOM   4223  C  C   . LEU A 1 577 ? 184.991 142.821 138.332 1.00 57.38  ? 570 LEU A C   1 
ATOM   4224  O  O   . LEU A 1 577 ? 184.763 143.779 139.077 1.00 57.38  ? 570 LEU A O   1 
ATOM   4225  C  CB  . LEU A 1 577 ? 187.308 143.092 137.423 1.00 57.38  ? 570 LEU A CB  1 
ATOM   4226  C  CG  . LEU A 1 577 ? 188.266 142.668 136.310 1.00 57.38  ? 570 LEU A CG  1 
ATOM   4227  C  CD1 . LEU A 1 577 ? 189.674 142.524 136.844 1.00 57.38  ? 570 LEU A CD1 1 
ATOM   4228  C  CD2 . LEU A 1 577 ? 187.805 141.372 135.677 1.00 57.38  ? 570 LEU A CD2 1 
ATOM   4229  N  N   . PHE A 1 578 ? 184.546 141.589 138.566 1.00 52.16  ? 571 PHE A N   1 
ATOM   4230  C  CA  . PHE A 1 578 ? 183.713 141.249 139.709 1.00 52.16  ? 571 PHE A CA  1 
ATOM   4231  C  C   . PHE A 1 578 ? 184.425 140.226 140.583 1.00 52.16  ? 571 PHE A C   1 
ATOM   4232  O  O   . PHE A 1 578 ? 185.189 139.391 140.093 1.00 52.16  ? 571 PHE A O   1 
ATOM   4233  C  CB  . PHE A 1 578 ? 182.357 140.690 139.264 1.00 52.16  ? 571 PHE A CB  1 
ATOM   4234  C  CG  . PHE A 1 578 ? 181.430 141.720 138.684 1.00 52.16  ? 571 PHE A CG  1 
ATOM   4235  C  CD1 . PHE A 1 578 ? 181.710 142.326 137.475 1.00 52.16  ? 571 PHE A CD1 1 
ATOM   4236  C  CD2 . PHE A 1 578 ? 180.268 142.072 139.346 1.00 52.16  ? 571 PHE A CD2 1 
ATOM   4237  C  CE1 . PHE A 1 578 ? 180.857 143.268 136.942 1.00 52.16  ? 571 PHE A CE1 1 
ATOM   4238  C  CE2 . PHE A 1 578 ? 179.411 143.012 138.815 1.00 52.16  ? 571 PHE A CE2 1 
ATOM   4239  C  CZ  . PHE A 1 578 ? 179.707 143.610 137.613 1.00 52.16  ? 571 PHE A CZ  1 
ATOM   4240  N  N   . LYS A 1 579 ? 184.168 140.301 141.886 1.00 56.98  ? 572 LYS A N   1 
ATOM   4241  C  CA  . LYS A 1 579 ? 184.722 139.349 142.839 1.00 56.98  ? 572 LYS A CA  1 
ATOM   4242  C  C   . LYS A 1 579 ? 183.637 138.903 143.805 1.00 56.98  ? 572 LYS A C   1 
ATOM   4243  O  O   . LYS A 1 579 ? 182.747 139.682 144.152 1.00 56.98  ? 572 LYS A O   1 
ATOM   4244  C  CB  . LYS A 1 579 ? 185.911 139.949 143.600 1.00 56.98  ? 572 LYS A CB  1 
ATOM   4245  C  CG  . LYS A 1 579 ? 185.665 141.332 144.181 1.00 56.98  ? 572 LYS A CG  1 
ATOM   4246  C  CD  . LYS A 1 579 ? 185.205 141.295 145.630 1.00 56.98  ? 572 LYS A CD  1 
ATOM   4247  C  CE  . LYS A 1 579 ? 185.257 142.689 146.238 1.00 56.98  ? 572 LYS A CE  1 
ATOM   4248  N  NZ  . LYS A 1 579 ? 184.672 142.748 147.604 1.00 56.98  ? 572 LYS A NZ  1 
ATOM   4249  N  N   . LEU A 1 580 ? 183.717 137.649 144.238 1.00 59.38  ? 573 LEU A N   1 
ATOM   4250  C  CA  . LEU A 1 580 ? 182.690 137.044 145.073 1.00 59.38  ? 573 LEU A CA  1 
ATOM   4251  C  C   . LEU A 1 580 ? 183.074 137.110 146.547 1.00 59.38  ? 573 LEU A C   1 
ATOM   4252  O  O   . LEU A 1 580 ? 184.245 136.992 146.915 1.00 59.38  ? 573 LEU A O   1 
ATOM   4253  C  CB  . LEU A 1 580 ? 182.436 135.592 144.664 1.00 59.38  ? 573 LEU A CB  1 
ATOM   4254  C  CG  . LEU A 1 580 ? 182.030 135.365 143.207 1.00 59.38  ? 573 LEU A CG  1 
ATOM   4255  C  CD1 . LEU A 1 580 ? 181.780 133.895 142.947 1.00 59.38  ? 573 LEU A CD1 1 
ATOM   4256  C  CD2 . LEU A 1 580 ? 180.805 136.184 142.851 1.00 59.38  ? 573 LEU A CD2 1 
ATOM   4257  N  N   . LYS A 1 581 ? 182.055 137.259 147.380 1.00 64.01  ? 574 LYS A N   1 
ATOM   4258  C  CA  . LYS A 1 581 ? 182.340 137.322 148.827 1.00 64.01  ? 574 LYS A CA  1 
ATOM   4259  C  C   . LYS A 1 581 ? 181.385 136.391 149.565 1.00 64.01  ? 574 LYS A C   1 
ATOM   4260  O  O   . LYS A 1 581 ? 180.887 135.434 148.946 1.00 64.01  ? 574 LYS A O   1 
ATOM   4261  C  CB  . LYS A 1 581 ? 182.193 138.766 149.318 1.00 64.01  ? 574 LYS A CB  1 
ATOM   4262  C  CG  . LYS A 1 581 ? 183.125 139.166 150.454 1.00 64.01  ? 574 LYS A CG  1 
ATOM   4263  C  CD  . LYS A 1 581 ? 184.586 138.963 150.118 1.00 64.01  ? 574 LYS A CD  1 
ATOM   4264  C  CE  . LYS A 1 581 ? 185.505 139.262 151.283 1.00 64.01  ? 574 LYS A CE  1 
ATOM   4265  N  NZ  . LYS A 1 581 ? 185.191 138.415 152.457 1.00 64.01  ? 574 LYS A NZ  1 
ATOM   4266  N  N   . GLU A 1 582 ? 181.104 136.762 150.821 1.00 69.86  ? 575 GLU A N   1 
ATOM   4267  C  CA  . GLU A 1 582 ? 180.179 135.981 151.676 1.00 69.86  ? 575 GLU A CA  1 
ATOM   4268  C  C   . GLU A 1 582 ? 178.952 135.571 150.869 1.00 69.86  ? 575 GLU A C   1 
ATOM   4269  O  O   . GLU A 1 582 ? 178.409 136.414 150.126 1.00 69.86  ? 575 GLU A O   1 
ATOM   4270  C  CB  . GLU A 1 582 ? 179.768 136.810 152.894 1.00 69.86  ? 575 GLU A CB  1 
ATOM   4271  C  CG  . GLU A 1 582 ? 180.950 137.335 153.687 1.00 69.86  ? 575 GLU A CG  1 
ATOM   4272  C  CD  . GLU A 1 582 ? 180.578 138.188 154.888 1.00 69.86  ? 575 GLU A CD  1 
ATOM   4273  O  OE1 . GLU A 1 582 ? 179.368 138.378 155.123 1.00 69.86  ? 575 GLU A OE1 1 
ATOM   4274  O  OE2 . GLU A 1 582 ? 181.498 138.660 155.583 1.00 69.86  ? 575 GLU A OE2 1 
ATOM   4275  N  N   . PHE A 1 583 ? 178.535 134.325 151.042 1.00 69.03  ? 576 PHE A N   1 
ATOM   4276  C  CA  . PHE A 1 583 ? 177.375 133.783 150.326 1.00 69.03  ? 576 PHE A CA  1 
ATOM   4277  C  C   . PHE A 1 583 ? 177.483 133.928 148.811 1.00 69.03  ? 576 PHE A C   1 
ATOM   4278  O  O   . PHE A 1 583 ? 176.466 133.878 148.111 1.00 69.03  ? 576 PHE A O   1 
ATOM   4279  C  CB  . PHE A 1 583 ? 176.051 134.381 150.824 1.00 69.03  ? 576 PHE A CB  1 
ATOM   4280  C  CG  . PHE A 1 583 ? 175.713 134.034 152.254 1.00 69.03  ? 576 PHE A CG  1 
ATOM   4281  C  CD1 . PHE A 1 583 ? 174.422 134.211 152.724 1.00 69.03  ? 576 PHE A CD1 1 
ATOM   4282  C  CD2 . PHE A 1 583 ? 176.648 133.453 153.098 1.00 69.03  ? 576 PHE A CD2 1 
ATOM   4283  C  CE1 . PHE A 1 583 ? 174.087 133.878 154.025 1.00 69.03  ? 576 PHE A CE1 1 
ATOM   4284  C  CE2 . PHE A 1 583 ? 176.320 133.117 154.401 1.00 69.03  ? 576 PHE A CE2 1 
ATOM   4285  C  CZ  . PHE A 1 583 ? 175.035 133.328 154.863 1.00 69.03  ? 576 PHE A CZ  1 
ATOM   4286  N  N   . SER A 1 584 ? 178.701 134.089 148.293 1.00 62.82  ? 577 SER A N   1 
ATOM   4287  C  CA  . SER A 1 584 ? 178.972 134.041 146.854 1.00 62.82  ? 577 SER A CA  1 
ATOM   4288  C  C   . SER A 1 584 ? 178.132 135.058 146.084 1.00 62.82  ? 577 SER A C   1 
ATOM   4289  O  O   . SER A 1 584 ? 177.320 134.708 145.226 1.00 62.82  ? 577 SER A O   1 
ATOM   4290  C  CB  . SER A 1 584 ? 178.757 132.628 146.308 1.00 62.82  ? 577 SER A CB  1 
ATOM   4291  O  OG  . SER A 1 584 ? 179.745 131.737 146.793 1.00 62.82  ? 577 SER A OG  1 
ATOM   4292  N  N   . LYS A 1 585 ? 178.337 136.332 146.397 1.00 56.83  ? 578 LYS A N   1 
ATOM   4293  C  CA  . LYS A 1 585 ? 177.698 137.431 145.691 1.00 56.83  ? 578 LYS A CA  1 
ATOM   4294  C  C   . LYS A 1 585 ? 178.760 138.339 145.085 1.00 56.83  ? 578 LYS A C   1 
ATOM   4295  O  O   . LYS A 1 585 ? 179.856 138.494 145.632 1.00 56.83  ? 578 LYS A O   1 
ATOM   4296  C  CB  . LYS A 1 585 ? 176.791 138.237 146.623 1.00 56.83  ? 578 LYS A CB  1 
ATOM   4297  C  CG  . LYS A 1 585 ? 175.753 137.411 147.361 1.00 56.83  ? 578 LYS A CG  1 
ATOM   4298  C  CD  . LYS A 1 585 ? 174.880 136.627 146.401 1.00 56.83  ? 578 LYS A CD  1 
ATOM   4299  C  CE  . LYS A 1 585 ? 173.820 135.839 147.149 1.00 56.83  ? 578 LYS A CE  1 
ATOM   4300  N  NZ  . LYS A 1 585 ? 172.911 135.107 146.228 1.00 56.83  ? 578 LYS A NZ  1 
ATOM   4301  N  N   . ALA A 1 586 ? 178.423 138.944 143.952 1.00 53.56  ? 579 ALA A N   1 
ATOM   4302  C  CA  . ALA A 1 586 ? 179.388 139.698 143.168 1.00 53.56  ? 579 ALA A CA  1 
ATOM   4303  C  C   . ALA A 1 586 ? 179.466 141.146 143.630 1.00 53.56  ? 579 ALA A C   1 
ATOM   4304  O  O   . ALA A 1 586 ? 178.446 141.783 143.903 1.00 53.56  ? 579 ALA A O   1 
ATOM   4305  C  CB  . ALA A 1 586 ? 179.024 139.649 141.684 1.00 53.56  ? 579 ALA A CB  1 
ATOM   4306  N  N   . GLU A 1 587 ? 180.692 141.658 143.711 1.00 60.02  ? 580 GLU A N   1 
ATOM   4307  C  CA  . GLU A 1 587 ? 180.952 143.062 143.980 1.00 60.02  ? 580 GLU A CA  1 
ATOM   4308  C  C   . GLU A 1 587 ? 181.958 143.566 142.958 1.00 60.02  ? 580 GLU A C   1 
ATOM   4309  O  O   . GLU A 1 587 ? 182.775 142.804 142.435 1.00 60.02  ? 580 GLU A O   1 
ATOM   4310  C  CB  . GLU A 1 587 ? 181.493 143.289 145.398 1.00 60.02  ? 580 GLU A CB  1 
ATOM   4311  C  CG  . GLU A 1 587 ? 180.442 143.274 146.489 1.00 60.02  ? 580 GLU A CG  1 
ATOM   4312  C  CD  . GLU A 1 587 ? 181.055 143.224 147.875 1.00 60.02  ? 580 GLU A CD  1 
ATOM   4313  O  OE1 . GLU A 1 587 ? 182.260 143.528 148.003 1.00 60.02  ? 580 GLU A OE1 1 
ATOM   4314  O  OE2 . GLU A 1 587 ? 180.335 142.877 148.834 1.00 60.02  ? 580 GLU A OE2 1 
ATOM   4315  N  N   . ALA A 1 588 ? 181.895 144.864 142.678 1.00 58.60  ? 581 ALA A N   1 
ATOM   4316  C  CA  . ALA A 1 588 ? 182.804 145.458 141.708 1.00 58.60  ? 581 ALA A CA  1 
ATOM   4317  C  C   . ALA A 1 588 ? 184.228 145.451 142.248 1.00 58.60  ? 581 ALA A C   1 
ATOM   4318  O  O   . ALA A 1 588 ? 184.494 145.971 143.335 1.00 58.60  ? 581 ALA A O   1 
ATOM   4319  C  CB  . ALA A 1 588 ? 182.367 146.883 141.380 1.00 58.60  ? 581 ALA A CB  1 
ATOM   4320  N  N   . PHE A 1 589 ? 185.148 144.855 141.486 1.00 65.18  ? 582 PHE A N   1 
ATOM   4321  C  CA  . PHE A 1 589 ? 186.541 144.804 141.916 1.00 65.18  ? 582 PHE A CA  1 
ATOM   4322  C  C   . PHE A 1 589 ? 187.152 146.200 141.951 1.00 65.18  ? 582 PHE A C   1 
ATOM   4323  O  O   . PHE A 1 589 ? 187.824 146.572 142.919 1.00 65.18  ? 582 PHE A O   1 
ATOM   4324  C  CB  . PHE A 1 589 ? 187.341 143.882 140.998 1.00 65.18  ? 582 PHE A CB  1 
ATOM   4325  C  CG  . PHE A 1 589 ? 188.753 143.659 141.447 1.00 65.18  ? 582 PHE A CG  1 
ATOM   4326  C  CD1 . PHE A 1 589 ? 189.020 142.990 142.628 1.00 65.18  ? 582 PHE A CD1 1 
ATOM   4327  C  CD2 . PHE A 1 589 ? 189.816 144.118 140.687 1.00 65.18  ? 582 PHE A CD2 1 
ATOM   4328  C  CE1 . PHE A 1 589 ? 190.319 142.784 143.044 1.00 65.18  ? 582 PHE A CE1 1 
ATOM   4329  C  CE2 . PHE A 1 589 ? 191.116 143.914 141.098 1.00 65.18  ? 582 PHE A CE2 1 
ATOM   4330  C  CZ  . PHE A 1 589 ? 191.368 143.246 142.277 1.00 65.18  ? 582 PHE A CZ  1 
ATOM   4331  N  N   . PHE A 1 590 ? 186.862 146.982 140.905 1.00 63.76  ? 583 PHE A N   1 
ATOM   4332  C  CA  . PHE A 1 590 ? 187.286 148.406 140.868 1.00 63.76  ? 583 PHE A CA  1 
ATOM   4333  C  C   . PHE A 1 590 ? 186.016 149.215 140.571 1.00 63.76  ? 583 PHE A C   1 
ATOM   4334  O  O   . PHE A 1 590 ? 185.030 148.595 140.127 1.00 63.76  ? 583 PHE A O   1 
ATOM   4335  C  CB  . PHE A 1 590 ? 188.433 148.604 139.872 1.00 63.76  ? 583 PHE A CB  1 
ATOM   4336  C  CG  . PHE A 1 590 ? 188.215 148.046 138.489 1.00 63.76  ? 583 PHE A CG  1 
ATOM   4337  C  CD1 . PHE A 1 590 ? 187.243 148.567 137.650 1.00 63.76  ? 583 PHE A CD1 1 
ATOM   4338  C  CD2 . PHE A 1 590 ? 188.992 146.998 138.021 1.00 63.76  ? 583 PHE A CD2 1 
ATOM   4339  C  CE1 . PHE A 1 590 ? 187.053 148.053 136.378 1.00 63.76  ? 583 PHE A CE1 1 
ATOM   4340  C  CE2 . PHE A 1 590 ? 188.800 146.484 136.748 1.00 63.76  ? 583 PHE A CE2 1 
ATOM   4341  C  CZ  . PHE A 1 590 ? 187.829 147.011 135.930 1.00 63.76  ? 583 PHE A CZ  1 
ATOM   4342  N  N   . PRO A 1 591 ? 185.965 150.549 140.783 1.00 65.60  ? 584 PRO A N   1 
ATOM   4343  C  CA  . PRO A 1 591 ? 184.717 151.311 140.613 1.00 65.60  ? 584 PRO A CA  1 
ATOM   4344  C  C   . PRO A 1 591 ? 183.898 150.900 139.379 1.00 65.60  ? 584 PRO A C   1 
ATOM   4345  O  O   . PRO A 1 591 ? 184.469 150.795 138.310 1.00 65.60  ? 584 PRO A O   1 
ATOM   4346  C  CB  . PRO A 1 591 ? 185.238 152.743 140.443 1.00 65.60  ? 584 PRO A CB  1 
ATOM   4347  C  CG  . PRO A 1 591 ? 186.469 152.780 141.320 1.00 65.60  ? 584 PRO A CG  1 
ATOM   4348  C  CD  . PRO A 1 591 ? 187.085 151.401 141.193 1.00 65.60  ? 584 PRO A CD  1 
ATOM   4349  N  N   . ASN A 1 592 ? 182.588 150.687 139.555 1.00 59.62  ? 585 ASN A N   1 
ATOM   4350  C  CA  . ASN A 1 592 ? 181.708 150.263 138.431 1.00 59.62  ? 585 ASN A CA  1 
ATOM   4351  C  C   . ASN A 1 592 ? 181.529 151.424 137.452 1.00 59.62  ? 585 ASN A C   1 
ATOM   4352  O  O   . ASN A 1 592 ? 180.953 152.447 137.859 1.00 59.62  ? 585 ASN A O   1 
ATOM   4353  C  CB  . ASN A 1 592 ? 180.351 149.749 138.915 1.00 59.62  ? 585 ASN A CB  1 
ATOM   4354  C  CG  . ASN A 1 592 ? 179.450 149.313 137.779 1.00 59.62  ? 585 ASN A CG  1 
ATOM   4355  O  OD1 . ASN A 1 592 ? 178.366 149.862 137.595 1.00 59.62  ? 585 ASN A OD1 1 
ATOM   4356  N  ND2 . ASN A 1 592 ? 179.889 148.330 137.012 1.00 59.62  ? 585 ASN A ND2 1 
ATOM   4357  N  N   . MET A 1 593 ? 181.989 151.258 136.210 1.00 57.97  ? 586 MET A N   1 
ATOM   4358  C  CA  . MET A 1 593 ? 181.892 152.307 135.205 1.00 57.97  ? 586 MET A CA  1 
ATOM   4359  C  C   . MET A 1 593 ? 180.641 152.193 134.350 1.00 57.97  ? 586 MET A C   1 
ATOM   4360  O  O   . MET A 1 593 ? 180.448 153.010 133.446 1.00 57.97  ? 586 MET A O   1 
ATOM   4361  C  CB  . MET A 1 593 ? 183.126 152.294 134.305 1.00 57.97  ? 586 MET A CB  1 
ATOM   4362  C  CG  . MET A 1 593 ? 184.417 152.018 135.044 1.00 57.97  ? 586 MET A CG  1 
ATOM   4363  S  SD  . MET A 1 593 ? 185.839 152.059 133.948 1.00 57.97  ? 586 MET A SD  1 
ATOM   4364  C  CE  . MET A 1 593 ? 185.160 152.998 132.591 1.00 57.97  ? 586 MET A CE  1 
ATOM   4365  N  N   . VAL A 1 594 ? 179.788 151.205 134.636 1.00 55.29  ? 587 VAL A N   1 
ATOM   4366  C  CA  . VAL A 1 594 ? 178.494 151.086 133.899 1.00 55.29  ? 587 VAL A CA  1 
ATOM   4367  C  C   . VAL A 1 594 ? 177.482 152.008 134.584 1.00 55.29  ? 587 VAL A C   1 
ATOM   4368  O  O   . VAL A 1 594 ? 176.654 152.605 133.876 1.00 55.29  ? 587 VAL A O   1 
ATOM   4369  C  CB  . VAL A 1 594 ? 178.007 149.625 133.861 1.00 55.29  ? 587 VAL A CB  1 
ATOM   4370  C  CG1 . VAL A 1 594 ? 176.633 149.496 133.223 1.00 55.29  ? 587 VAL A CG1 1 
ATOM   4371  C  CG2 . VAL A 1 594 ? 179.009 148.734 133.146 1.00 55.29  ? 587 VAL A CG2 1 
ATOM   4372  N  N   . ASN A 1 595 ? 177.562 152.126 135.910 1.00 58.35  ? 588 ASN A N   1 
ATOM   4373  C  CA  . ASN A 1 595 ? 176.669 152.996 136.672 1.00 58.35  ? 588 ASN A CA  1 
ATOM   4374  C  C   . ASN A 1 595 ? 177.178 154.430 136.555 1.00 58.35  ? 588 ASN A C   1 
ATOM   4375  O  O   . ASN A 1 595 ? 177.822 154.975 137.454 1.00 58.35  ? 588 ASN A O   1 
ATOM   4376  C  CB  . ASN A 1 595 ? 176.595 152.543 138.123 1.00 58.35  ? 588 ASN A CB  1 
ATOM   4377  C  CG  . ASN A 1 595 ? 175.283 152.909 138.781 1.00 58.35  ? 588 ASN A CG  1 
ATOM   4378  O  OD1 . ASN A 1 595 ? 174.295 153.194 138.105 1.00 58.35  ? 588 ASN A OD1 1 
ATOM   4379  N  ND2 . ASN A 1 595 ? 175.266 152.904 140.108 1.00 58.35  ? 588 ASN A ND2 1 
ATOM   4380  N  N   . MET A 1 596 ? 176.871 155.019 135.398 1.00 56.40  ? 589 MET A N   1 
ATOM   4381  C  CA  . MET A 1 596 ? 177.326 156.405 135.139 1.00 56.40  ? 589 MET A CA  1 
ATOM   4382  C  C   . MET A 1 596 ? 176.112 157.322 134.998 1.00 56.40  ? 589 MET A C   1 
ATOM   4383  O  O   . MET A 1 596 ? 174.997 156.804 134.793 1.00 56.40  ? 589 MET A O   1 
ATOM   4384  C  CB  . MET A 1 596 ? 178.163 156.473 133.857 1.00 56.40  ? 589 MET A CB  1 
ATOM   4385  C  CG  . MET A 1 596 ? 177.766 155.440 132.822 1.00 56.40  ? 589 MET A CG  1 
ATOM   4386  S  SD  . MET A 1 596 ? 178.801 155.498 131.338 1.00 56.40  ? 589 MET A SD  1 
ATOM   4387  C  CE  . MET A 1 596 ? 177.651 154.873 130.114 1.00 56.40  ? 589 MET A CE  1 
ATOM   4388  N  N   . LEU A 1 597 ? 176.333 158.625 135.105 1.00 54.34  ? 590 LEU A N   1 
ATOM   4389  C  CA  . LEU A 1 597 ? 175.294 159.637 134.996 1.00 54.34  ? 590 LEU A CA  1 
ATOM   4390  C  C   . LEU A 1 597 ? 175.275 160.188 133.578 1.00 54.34  ? 590 LEU A C   1 
ATOM   4391  O  O   . LEU A 1 597 ? 176.280 160.726 133.106 1.00 54.34  ? 590 LEU A O   1 
ATOM   4392  C  CB  . LEU A 1 597 ? 175.533 160.766 135.997 1.00 54.34  ? 590 LEU A CB  1 
ATOM   4393  C  CG  . LEU A 1 597 ? 174.474 161.864 136.038 1.00 54.34  ? 590 LEU A CG  1 
ATOM   4394  C  CD1 . LEU A 1 597 ? 173.213 161.335 136.684 1.00 54.34  ? 590 LEU A CD1 1 
ATOM   4395  C  CD2 . LEU A 1 597 ? 174.994 163.081 136.782 1.00 54.34  ? 590 LEU A CD2 1 
ATOM   4396  N  N   . VAL A 1 598 ? 174.137 160.060 132.904 1.00 51.26  ? 591 VAL A N   1 
ATOM   4397  C  CA  . VAL A 1 598 ? 173.984 160.521 131.528 1.00 51.26  ? 591 VAL A CA  1 
ATOM   4398  C  C   . VAL A 1 598 ? 173.083 161.750 131.526 1.00 51.26  ? 591 VAL A C   1 
ATOM   4399  O  O   . VAL A 1 598 ? 171.969 161.723 132.065 1.00 51.26  ? 591 VAL A O   1 
ATOM   4400  C  CB  . VAL A 1 598 ? 173.453 159.404 130.611 1.00 51.26  ? 591 VAL A CB  1 
ATOM   4401  C  CG1 . VAL A 1 598 ? 172.056 158.961 131.011 1.00 51.26  ? 591 VAL A CG1 1 
ATOM   4402  C  CG2 . VAL A 1 598 ? 173.459 159.865 129.165 1.00 51.26  ? 591 VAL A CG2 1 
ATOM   4403  N  N   . LEU A 1 599 ? 173.583 162.844 130.950 1.00 51.87  ? 592 LEU A N   1 
ATOM   4404  C  CA  . LEU A 1 599 ? 172.861 164.111 130.864 1.00 51.87  ? 592 LEU A CA  1 
ATOM   4405  C  C   . LEU A 1 599 ? 172.941 164.555 129.408 1.00 51.87  ? 592 LEU A C   1 
ATOM   4406  O  O   . LEU A 1 599 ? 173.906 165.210 129.004 1.00 51.87  ? 592 LEU A O   1 
ATOM   4407  C  CB  . LEU A 1 599 ? 173.452 165.155 131.809 1.00 51.87  ? 592 LEU A CB  1 
ATOM   4408  C  CG  . LEU A 1 599 ? 173.348 164.925 133.317 1.00 51.87  ? 592 LEU A CG  1 
ATOM   4409  C  CD1 . LEU A 1 599 ? 173.998 166.073 134.064 1.00 51.87  ? 592 LEU A CD1 1 
ATOM   4410  C  CD2 . LEU A 1 599 ? 171.903 164.774 133.745 1.00 51.87  ? 592 LEU A CD2 1 
ATOM   4411  N  N   . GLY A 1 600 ? 171.933 164.191 128.621 1.00 56.11  ? 593 GLY A N   1 
ATOM   4412  C  CA  . GLY A 1 600 ? 171.939 164.517 127.210 1.00 56.11  ? 593 GLY A CA  1 
ATOM   4413  C  C   . GLY A 1 600 ? 173.097 163.867 126.484 1.00 56.11  ? 593 GLY A C   1 
ATOM   4414  O  O   . GLY A 1 600 ? 173.111 162.651 126.283 1.00 56.11  ? 593 GLY A O   1 
ATOM   4415  N  N   . LYS A 1 601 ? 174.079 164.672 126.087 1.00 62.14  ? 594 LYS A N   1 
ATOM   4416  C  CA  . LYS A 1 601 ? 175.281 164.176 125.433 1.00 62.14  ? 594 LYS A CA  1 
ATOM   4417  C  C   . LYS A 1 601 ? 176.511 164.272 126.325 1.00 62.14  ? 594 LYS A C   1 
ATOM   4418  O  O   . LYS A 1 601 ? 177.636 164.257 125.816 1.00 62.14  ? 594 LYS A O   1 
ATOM   4419  C  CB  . LYS A 1 601 ? 175.520 164.929 124.123 1.00 62.14  ? 594 LYS A CB  1 
ATOM   4420  C  CG  . LYS A 1 601 ? 174.255 165.206 123.330 1.00 62.14  ? 594 LYS A CG  1 
ATOM   4421  C  CD  . LYS A 1 601 ? 174.501 166.237 122.241 1.00 62.14  ? 594 LYS A CD  1 
ATOM   4422  C  CE  . LYS A 1 601 ? 173.531 166.060 121.086 1.00 62.14  ? 594 LYS A CE  1 
ATOM   4423  N  NZ  . LYS A 1 601 ? 173.395 164.630 120.693 1.00 62.14  ? 594 LYS A NZ  1 
ATOM   4424  N  N   . HIS A 1 602 ? 176.329 164.370 127.639 1.00 64.45  ? 595 HIS A N   1 
ATOM   4425  C  CA  . HIS A 1 602 ? 177.432 164.489 128.580 1.00 64.45  ? 595 HIS A CA  1 
ATOM   4426  C  C   . HIS A 1 602 ? 177.393 163.326 129.562 1.00 64.45  ? 595 HIS A C   1 
ATOM   4427  O  O   . HIS A 1 602 ? 176.316 162.855 129.942 1.00 64.45  ? 595 HIS A O   1 
ATOM   4428  C  CB  . HIS A 1 602 ? 177.371 165.825 129.326 1.00 64.45  ? 595 HIS A CB  1 
ATOM   4429  C  CG  . HIS A 1 602 ? 177.419 167.017 128.422 1.00 64.45  ? 595 HIS A CG  1 
ATOM   4430  N  ND1 . HIS A 1 602 ? 178.511 167.311 127.634 1.00 64.45  ? 595 HIS A ND1 1 
ATOM   4431  C  CD2 . HIS A 1 602 ? 176.507 167.987 128.175 1.00 64.45  ? 595 HIS A CD2 1 
ATOM   4432  C  CE1 . HIS A 1 602 ? 178.270 168.410 126.942 1.00 64.45  ? 595 HIS A CE1 1 
ATOM   4433  N  NE2 . HIS A 1 602 ? 177.061 168.841 127.254 1.00 64.45  ? 595 HIS A NE2 1 
ATOM   4434  N  N   . LEU A 1 603 ? 178.572 162.860 129.966 1.00 64.41  ? 596 LEU A N   1 
ATOM   4435  C  CA  . LEU A 1 603 ? 178.691 161.656 130.775 1.00 64.41  ? 596 LEU A CA  1 
ATOM   4436  C  C   . LEU A 1 603 ? 179.545 161.926 132.004 1.00 64.41  ? 596 LEU A C   1 
ATOM   4437  O  O   . LEU A 1 603 ? 180.644 162.479 131.893 1.00 64.41  ? 596 LEU A O   1 
ATOM   4438  C  CB  . LEU A 1 603 ? 179.305 160.513 129.963 1.00 64.41  ? 596 LEU A CB  1 
ATOM   4439  C  CG  . LEU A 1 603 ? 178.481 159.959 128.803 1.00 64.41  ? 596 LEU A CG  1 
ATOM   4440  C  CD1 . LEU A 1 603 ? 179.079 158.655 128.317 1.00 64.41  ? 596 LEU A CD1 1 
ATOM   4441  C  CD2 . LEU A 1 603 ? 177.041 159.757 129.220 1.00 64.41  ? 596 LEU A CD2 1 
ATOM   4442  N  N   . GLY A 1 604 ? 179.033 161.540 133.169 1.00 63.24  ? 597 GLY A N   1 
ATOM   4443  C  CA  . GLY A 1 604 ? 179.833 161.449 134.372 1.00 63.24  ? 597 GLY A CA  1 
ATOM   4444  C  C   . GLY A 1 604 ? 180.069 159.995 134.722 1.00 63.24  ? 597 GLY A C   1 
ATOM   4445  O  O   . GLY A 1 604 ? 179.162 159.312 135.207 1.00 63.24  ? 597 GLY A O   1 
ATOM   4446  N  N   . ILE A 1 605 ? 181.276 159.510 134.474 1.00 63.69  ? 598 ILE A N   1 
ATOM   4447  C  CA  . ILE A 1 605 ? 181.629 158.102 134.635 1.00 63.69  ? 598 ILE A CA  1 
ATOM   4448  C  C   . ILE A 1 605 ? 182.513 157.972 135.868 1.00 63.69  ? 598 ILE A C   1 
ATOM   4449  O  O   . ILE A 1 605 ? 183.462 158.749 136.015 1.00 63.69  ? 598 ILE A O   1 
ATOM   4450  C  CB  . ILE A 1 605 ? 182.352 157.551 133.393 1.00 63.69  ? 598 ILE A CB  1 
ATOM   4451  C  CG1 . ILE A 1 605 ? 181.544 157.850 132.131 1.00 63.69  ? 598 ILE A CG1 1 
ATOM   4452  C  CG2 . ILE A 1 605 ? 182.593 156.063 133.532 1.00 63.69  ? 598 ILE A CG2 1 
ATOM   4453  C  CD1 . ILE A 1 605 ? 182.248 157.465 130.857 1.00 63.69  ? 598 ILE A CD1 1 
ATOM   4454  N  N   . PRO A 1 606 ? 182.236 157.035 136.772 1.00 60.25  ? 599 PRO A N   1 
ATOM   4455  C  CA  . PRO A 1 606 ? 183.121 156.847 137.926 1.00 60.25  ? 599 PRO A CA  1 
ATOM   4456  C  C   . PRO A 1 606 ? 184.534 156.505 137.483 1.00 60.25  ? 599 PRO A C   1 
ATOM   4457  O  O   . PRO A 1 606 ? 184.742 155.709 136.566 1.00 60.25  ? 599 PRO A O   1 
ATOM   4458  C  CB  . PRO A 1 606 ? 182.473 155.685 138.684 1.00 60.25  ? 599 PRO A CB  1 
ATOM   4459  C  CG  . PRO A 1 606 ? 181.053 155.713 138.265 1.00 60.25  ? 599 PRO A CG  1 
ATOM   4460  C  CD  . PRO A 1 606 ? 181.054 156.163 136.838 1.00 60.25  ? 599 PRO A CD  1 
ATOM   4461  N  N   . LYS A 1 607 ? 185.508 157.111 138.149 1.00 73.34  ? 600 LYS A N   1 
ATOM   4462  C  CA  . LYS A 1 607 ? 186.901 156.922 137.770 1.00 73.34  ? 600 LYS A CA  1 
ATOM   4463  C  C   . LYS A 1 607 ? 187.380 155.553 138.236 1.00 73.34  ? 600 LYS A C   1 
ATOM   4464  O  O   . LYS A 1 607 ? 187.352 155.276 139.439 1.00 73.34  ? 600 LYS A O   1 
ATOM   4465  C  CB  . LYS A 1 607 ? 187.771 158.018 138.369 1.00 73.34  ? 600 LYS A CB  1 
ATOM   4466  C  CG  . LYS A 1 607 ? 189.074 158.243 137.625 1.00 73.34  ? 600 LYS A CG  1 
ATOM   4467  C  CD  . LYS A 1 607 ? 189.736 159.544 138.039 1.00 73.34  ? 600 LYS A CD  1 
ATOM   4468  C  CE  . LYS A 1 607 ? 191.020 159.774 137.264 1.00 73.34  ? 600 LYS A CE  1 
ATOM   4469  N  NZ  . LYS A 1 607 ? 192.059 158.767 137.609 1.00 73.34  ? 600 LYS A NZ  1 
ATOM   4470  N  N   . PRO A 1 608 ? 187.830 154.679 137.333 1.00 72.35  ? 601 PRO A N   1 
ATOM   4471  C  CA  . PRO A 1 608 ? 188.247 153.337 137.759 1.00 72.35  ? 601 PRO A CA  1 
ATOM   4472  C  C   . PRO A 1 608 ? 189.596 153.306 138.442 1.00 72.35  ? 601 PRO A C   1 
ATOM   4473  O  O   . PRO A 1 608 ? 189.889 152.327 139.139 1.00 72.35  ? 601 PRO A O   1 
ATOM   4474  C  CB  . PRO A 1 608 ? 188.284 152.556 136.443 1.00 72.35  ? 601 PRO A CB  1 
ATOM   4475  C  CG  . PRO A 1 608 ? 188.664 153.590 135.442 1.00 72.35  ? 601 PRO A CG  1 
ATOM   4476  C  CD  . PRO A 1 608 ? 187.989 154.867 135.882 1.00 72.35  ? 601 PRO A CD  1 
ATOM   4477  N  N   . PHE A 1 609 ? 190.421 154.338 138.267 1.00 86.50  ? 602 PHE A N   1 
ATOM   4478  C  CA  . PHE A 1 609 ? 191.804 154.335 138.743 1.00 86.50  ? 602 PHE A CA  1 
ATOM   4479  C  C   . PHE A 1 609 ? 192.565 153.133 138.190 1.00 86.50  ? 602 PHE A C   1 
ATOM   4480  O  O   . PHE A 1 609 ? 193.346 152.484 138.889 1.00 86.50  ? 602 PHE A O   1 
ATOM   4481  C  CB  . PHE A 1 609 ? 191.866 154.371 140.270 1.00 86.50  ? 602 PHE A CB  1 
ATOM   4482  C  CG  . PHE A 1 609 ? 191.503 155.702 140.856 1.00 86.50  ? 602 PHE A CG  1 
ATOM   4483  C  CD1 . PHE A 1 609 ? 192.264 156.824 140.581 1.00 86.50  ? 602 PHE A CD1 1 
ATOM   4484  C  CD2 . PHE A 1 609 ? 190.398 155.832 141.678 1.00 86.50  ? 602 PHE A CD2 1 
ATOM   4485  C  CE1 . PHE A 1 609 ? 191.931 158.052 141.116 1.00 86.50  ? 602 PHE A CE1 1 
ATOM   4486  C  CE2 . PHE A 1 609 ? 190.060 157.057 142.218 1.00 86.50  ? 602 PHE A CE2 1 
ATOM   4487  C  CZ  . PHE A 1 609 ? 190.827 158.169 141.936 1.00 86.50  ? 602 PHE A CZ  1 
ATOM   4488  N  N   . GLY A 1 610 ? 192.329 152.832 136.913 1.00 90.15  ? 603 GLY A N   1 
ATOM   4489  C  CA  . GLY A 1 610 ? 192.993 151.730 136.263 1.00 90.15  ? 603 GLY A CA  1 
ATOM   4490  C  C   . GLY A 1 610 ? 194.444 152.034 135.971 1.00 90.15  ? 603 GLY A C   1 
ATOM   4491  O  O   . GLY A 1 610 ? 194.920 153.170 136.100 1.00 90.15  ? 603 GLY A O   1 
ATOM   4492  N  N   . PRO A 1 611 ? 195.178 150.995 135.571 1.00 91.37  ? 604 PRO A N   1 
ATOM   4493  C  CA  . PRO A 1 611 ? 196.609 151.164 135.296 1.00 91.37  ? 604 PRO A CA  1 
ATOM   4494  C  C   . PRO A 1 611 ? 196.845 152.166 134.178 1.00 91.37  ? 604 PRO A C   1 
ATOM   4495  O  O   . PRO A 1 611 ? 196.087 152.241 133.209 1.00 91.37  ? 604 PRO A O   1 
ATOM   4496  C  CB  . PRO A 1 611 ? 197.063 149.757 134.892 1.00 91.37  ? 604 PRO A CB  1 
ATOM   4497  C  CG  . PRO A 1 611 ? 196.008 148.843 135.428 1.00 91.37  ? 604 PRO A CG  1 
ATOM   4498  C  CD  . PRO A 1 611 ? 194.732 149.613 135.339 1.00 91.37  ? 604 PRO A CD  1 
ATOM   4499  N  N   . VAL A 1 612 ? 197.917 152.941 134.320 1.00 95.02  ? 605 VAL A N   1 
ATOM   4500  C  CA  . VAL A 1 612 ? 198.236 154.026 133.400 1.00 95.02  ? 605 VAL A CA  1 
ATOM   4501  C  C   . VAL A 1 612 ? 199.425 153.618 132.541 1.00 95.02  ? 605 VAL A C   1 
ATOM   4502  O  O   . VAL A 1 612 ? 200.345 152.939 133.013 1.00 95.02  ? 605 VAL A O   1 
ATOM   4503  C  CB  . VAL A 1 612 ? 198.506 155.345 134.149 1.00 95.02  ? 605 VAL A CB  1 
ATOM   4504  C  CG1 . VAL A 1 612 ? 197.414 155.601 135.174 1.00 95.02  ? 605 VAL A CG1 1 
ATOM   4505  C  CG2 . VAL A 1 612 ? 199.871 155.330 134.822 1.00 95.02  ? 605 VAL A CG2 1 
ATOM   4506  N  N   . ILE A 1 613 ? 199.375 153.996 131.268 1.00 99.47  ? 606 ILE A N   1 
ATOM   4507  C  CA  . ILE A 1 613 ? 200.469 153.829 130.323 1.00 99.47  ? 606 ILE A CA  1 
ATOM   4508  C  C   . ILE A 1 613 ? 200.658 155.159 129.608 1.00 99.47  ? 606 ILE A C   1 
ATOM   4509  O  O   . ILE A 1 613 ? 199.676 155.796 129.207 1.00 99.47  ? 606 ILE A O   1 
ATOM   4510  C  CB  . ILE A 1 613 ? 200.188 152.695 129.318 1.00 99.47  ? 606 ILE A CB  1 
ATOM   4511  C  CG1 . ILE A 1 613 ? 201.172 152.747 128.148 1.00 99.47  ? 606 ILE A CG1 1 
ATOM   4512  C  CG2 . ILE A 1 613 ? 198.751 152.758 128.824 1.00 99.47  ? 606 ILE A CG2 1 
ATOM   4513  C  CD1 . ILE A 1 613 ? 201.386 151.411 127.475 1.00 99.47  ? 606 ILE A CD1 1 
ATOM   4514  N  N   . ASN A 1 614 ? 201.914 155.598 129.491 1.00 103.86 ? 607 ASN A N   1 
ATOM   4515  C  CA  . ASN A 1 614 ? 202.259 156.835 128.786 1.00 103.86 ? 607 ASN A CA  1 
ATOM   4516  C  C   . ASN A 1 614 ? 201.443 158.018 129.302 1.00 103.86 ? 607 ASN A C   1 
ATOM   4517  O  O   . ASN A 1 614 ? 201.018 158.887 128.538 1.00 103.86 ? 607 ASN A O   1 
ATOM   4518  C  CB  . ASN A 1 614 ? 202.086 156.672 127.275 1.00 103.86 ? 607 ASN A CB  1 
ATOM   4519  C  CG  . ASN A 1 614 ? 202.882 155.507 126.721 1.00 103.86 ? 607 ASN A CG  1 
ATOM   4520  O  OD1 . ASN A 1 614 ? 203.767 154.972 127.389 1.00 103.86 ? 607 ASN A OD1 1 
ATOM   4521  N  ND2 . ASN A 1 614 ? 202.570 155.107 125.494 1.00 103.86 ? 607 ASN A ND2 1 
ATOM   4522  N  N   . GLY A 1 615 ? 201.225 158.051 130.612 1.00 101.72 ? 608 GLY A N   1 
ATOM   4523  C  CA  . GLY A 1 615 ? 200.452 159.115 131.229 1.00 101.72 ? 608 GLY A CA  1 
ATOM   4524  C  C   . GLY A 1 615 ? 198.980 159.143 130.873 1.00 101.72 ? 608 GLY A C   1 
ATOM   4525  O  O   . GLY A 1 615 ? 198.396 160.229 130.770 1.00 101.72 ? 608 GLY A O   1 
ATOM   4526  N  N   . ARG A 1 616 ? 198.362 157.977 130.684 1.00 93.39  ? 609 ARG A N   1 
ATOM   4527  C  CA  . ARG A 1 616 ? 196.911 157.909 130.542 1.00 93.39  ? 609 ARG A CA  1 
ATOM   4528  C  C   . ARG A 1 616 ? 196.456 156.504 130.898 1.00 93.39  ? 609 ARG A C   1 
ATOM   4529  O  O   . ARG A 1 616 ? 197.093 155.530 130.495 1.00 93.39  ? 609 ARG A O   1 
ATOM   4530  C  CB  . ARG A 1 616 ? 196.463 158.273 129.124 1.00 93.39  ? 609 ARG A CB  1 
ATOM   4531  C  CG  . ARG A 1 616 ? 194.954 158.290 128.958 1.00 93.39  ? 609 ARG A CG  1 
ATOM   4532  C  CD  . ARG A 1 616 ? 194.504 159.418 128.044 1.00 93.39  ? 609 ARG A CD  1 
ATOM   4533  N  NE  . ARG A 1 616 ? 193.114 159.268 127.627 1.00 93.39  ? 609 ARG A NE  1 
ATOM   4534  C  CZ  . ARG A 1 616 ? 192.067 159.431 128.424 1.00 93.39  ? 609 ARG A CZ  1 
ATOM   4535  N  NH1 . ARG A 1 616 ? 192.210 159.761 129.697 1.00 93.39  ? 609 ARG A NH1 1 
ATOM   4536  N  NH2 . ARG A 1 616 ? 190.844 159.262 127.930 1.00 93.39  ? 609 ARG A NH2 1 
ATOM   4537  N  N   . CYS A 1 617 ? 195.370 156.400 131.658 1.00 89.11  ? 610 CYS A N   1 
ATOM   4538  C  CA  . CYS A 1 617 ? 194.903 155.092 132.095 1.00 89.11  ? 610 CYS A CA  1 
ATOM   4539  C  C   . CYS A 1 617 ? 194.309 154.317 130.925 1.00 89.11  ? 610 CYS A C   1 
ATOM   4540  O  O   . CYS A 1 617 ? 193.553 154.863 130.117 1.00 89.11  ? 610 CYS A O   1 
ATOM   4541  C  CB  . CYS A 1 617 ? 193.870 155.234 133.210 1.00 89.11  ? 610 CYS A CB  1 
ATOM   4542  S  SG  . CYS A 1 617 ? 192.741 153.834 133.336 1.00 89.11  ? 610 CYS A SG  1 
ATOM   4543  N  N   . CYS A 1 618 ? 194.659 153.031 130.840 1.00 84.00  ? 611 CYS A N   1 
ATOM   4544  C  CA  . CYS A 1 618 ? 194.206 152.210 129.721 1.00 84.00  ? 611 CYS A CA  1 
ATOM   4545  C  C   . CYS A 1 618 ? 192.691 152.047 129.726 1.00 84.00  ? 611 CYS A C   1 
ATOM   4546  O  O   . CYS A 1 618 ? 192.057 152.061 128.666 1.00 84.00  ? 611 CYS A O   1 
ATOM   4547  C  CB  . CYS A 1 618 ? 194.892 150.846 129.760 1.00 84.00  ? 611 CYS A CB  1 
ATOM   4548  S  SG  . CYS A 1 618 ? 194.749 149.985 131.339 1.00 84.00  ? 611 CYS A SG  1 
ATOM   4549  N  N   . LEU A 1 619 ? 192.096 151.880 130.909 1.00 77.51  ? 612 LEU A N   1 
ATOM   4550  C  CA  . LEU A 1 619 ? 190.647 151.720 130.994 1.00 77.51  ? 612 LEU A CA  1 
ATOM   4551  C  C   . LEU A 1 619 ? 189.922 152.960 130.486 1.00 77.51  ? 612 LEU A C   1 
ATOM   4552  O  O   . LEU A 1 619 ? 188.993 152.860 129.671 1.00 77.51  ? 612 LEU A O   1 
ATOM   4553  C  CB  . LEU A 1 619 ? 190.245 151.423 132.437 1.00 77.51  ? 612 LEU A CB  1 
ATOM   4554  C  CG  . LEU A 1 619 ? 189.973 149.965 132.796 1.00 77.51  ? 612 LEU A CG  1 
ATOM   4555  C  CD1 . LEU A 1 619 ? 189.801 149.814 134.294 1.00 77.51  ? 612 LEU A CD1 1 
ATOM   4556  C  CD2 . LEU A 1 619 ? 188.737 149.489 132.073 1.00 77.51  ? 612 LEU A CD2 1 
ATOM   4557  N  N   . GLU A 1 620 ? 190.335 154.140 130.957 1.00 81.33  ? 613 GLU A N   1 
ATOM   4558  C  CA  . GLU A 1 620 ? 189.706 155.376 130.508 1.00 81.33  ? 613 GLU A CA  1 
ATOM   4559  C  C   . GLU A 1 620 ? 189.905 155.580 129.014 1.00 81.33  ? 613 GLU A C   1 
ATOM   4560  O  O   . GLU A 1 620 ? 188.978 155.992 128.311 1.00 81.33  ? 613 GLU A O   1 
ATOM   4561  C  CB  . GLU A 1 620 ? 190.259 156.568 131.287 1.00 81.33  ? 613 GLU A CB  1 
ATOM   4562  C  CG  . GLU A 1 620 ? 190.426 156.327 132.772 1.00 81.33  ? 613 GLU A CG  1 
ATOM   4563  C  CD  . GLU A 1 620 ? 190.543 157.616 133.558 1.00 81.33  ? 613 GLU A CD  1 
ATOM   4564  O  OE1 . GLU A 1 620 ? 190.653 158.688 132.929 1.00 81.33  ? 613 GLU A OE1 1 
ATOM   4565  O  OE2 . GLU A 1 620 ? 190.532 157.557 134.805 1.00 81.33  ? 613 GLU A OE2 1 
ATOM   4566  N  N   . GLU A 1 621 ? 191.109 155.302 128.511 1.00 84.31  ? 614 GLU A N   1 
ATOM   4567  C  CA  . GLU A 1 621 ? 191.370 155.461 127.084 1.00 84.31  ? 614 GLU A CA  1 
ATOM   4568  C  C   . GLU A 1 621 ? 190.478 154.544 126.259 1.00 84.31  ? 614 GLU A C   1 
ATOM   4569  O  O   . GLU A 1 621 ? 189.899 154.963 125.250 1.00 84.31  ? 614 GLU A O   1 
ATOM   4570  C  CB  . GLU A 1 621 ? 192.844 155.188 126.787 1.00 84.31  ? 614 GLU A CB  1 
ATOM   4571  C  CG  . GLU A 1 621 ? 193.208 155.261 125.313 1.00 84.31  ? 614 GLU A CG  1 
ATOM   4572  C  CD  . GLU A 1 621 ? 193.362 156.685 124.815 1.00 84.31  ? 614 GLU A CD  1 
ATOM   4573  O  OE1 . GLU A 1 621 ? 193.265 157.620 125.637 1.00 84.31  ? 614 GLU A OE1 1 
ATOM   4574  O  OE2 . GLU A 1 621 ? 193.580 156.869 123.600 1.00 84.31  ? 614 GLU A OE2 1 
ATOM   4575  N  N   . LYS A 1 622 ? 190.349 153.285 126.680 1.00 78.82  ? 615 LYS A N   1 
ATOM   4576  C  CA  . LYS A 1 622 ? 189.523 152.333 125.945 1.00 78.82  ? 615 LYS A CA  1 
ATOM   4577  C  C   . LYS A 1 622 ? 188.064 152.767 125.936 1.00 78.82  ? 615 LYS A C   1 
ATOM   4578  O  O   . LYS A 1 622 ? 187.408 152.764 124.888 1.00 78.82  ? 615 LYS A O   1 
ATOM   4579  C  CB  . LYS A 1 622 ? 189.668 150.940 126.558 1.00 78.82  ? 615 LYS A CB  1 
ATOM   4580  C  CG  . LYS A 1 622 ? 188.639 149.932 126.080 1.00 78.82  ? 615 LYS A CG  1 
ATOM   4581  C  CD  . LYS A 1 622 ? 188.879 149.535 124.635 1.00 78.82  ? 615 LYS A CD  1 
ATOM   4582  C  CE  . LYS A 1 622 ? 187.840 148.533 124.163 1.00 78.82  ? 615 LYS A CE  1 
ATOM   4583  N  NZ  . LYS A 1 622 ? 187.833 147.305 125.004 1.00 78.82  ? 615 LYS A NZ  1 
ATOM   4584  N  N   . VAL A 1 623 ? 187.542 153.166 127.096 1.00 75.74  ? 616 VAL A N   1 
ATOM   4585  C  CA  . VAL A 1 623 ? 186.130 153.534 127.172 1.00 75.74  ? 616 VAL A CA  1 
ATOM   4586  C  C   . VAL A 1 623 ? 185.872 154.824 126.401 1.00 75.74  ? 616 VAL A C   1 
ATOM   4587  O  O   . VAL A 1 623 ? 184.825 154.987 125.762 1.00 75.74  ? 616 VAL A O   1 
ATOM   4588  C  CB  . VAL A 1 623 ? 185.684 153.635 128.639 1.00 75.74  ? 616 VAL A CB  1 
ATOM   4589  C  CG1 . VAL A 1 623 ? 184.272 154.180 128.735 1.00 75.74  ? 616 VAL A CG1 1 
ATOM   4590  C  CG2 . VAL A 1 623 ? 185.764 152.268 129.276 1.00 75.74  ? 616 VAL A CG2 1 
ATOM   4591  N  N   . CYS A 1 624 ? 186.823 155.759 126.443 1.00 79.45  ? 617 CYS A N   1 
ATOM   4592  C  CA  . CYS A 1 624 ? 186.675 156.999 125.690 1.00 79.45  ? 617 CYS A CA  1 
ATOM   4593  C  C   . CYS A 1 624 ? 186.703 156.736 124.191 1.00 79.45  ? 617 CYS A C   1 
ATOM   4594  O  O   . CYS A 1 624 ? 185.928 157.325 123.433 1.00 79.45  ? 617 CYS A O   1 
ATOM   4595  C  CB  . CYS A 1 624 ? 187.769 157.989 126.088 1.00 79.45  ? 617 CYS A CB  1 
ATOM   4596  S  SG  . CYS A 1 624 ? 187.703 159.566 125.206 1.00 79.45  ? 617 CYS A SG  1 
ATOM   4597  N  N   . SER A 1 625 ? 187.591 155.847 123.740 1.00 76.07  ? 618 SER A N   1 
ATOM   4598  C  CA  . SER A 1 625 ? 187.623 155.490 122.328 1.00 76.07  ? 618 SER A CA  1 
ATOM   4599  C  C   . SER A 1 625 ? 186.420 154.660 121.909 1.00 76.07  ? 618 SER A C   1 
ATOM   4600  O  O   . SER A 1 625 ? 186.127 154.585 120.711 1.00 76.07  ? 618 SER A O   1 
ATOM   4601  C  CB  . SER A 1 625 ? 188.909 154.730 122.005 1.00 76.07  ? 618 SER A CB  1 
ATOM   4602  O  OG  . SER A 1 625 ? 188.881 154.230 120.680 1.00 76.07  ? 618 SER A OG  1 
ATOM   4603  N  N   . LEU A 1 626 ? 185.731 154.027 122.857 1.00 72.49  ? 619 LEU A N   1 
ATOM   4604  C  CA  . LEU A 1 626 ? 184.534 153.257 122.550 1.00 72.49  ? 619 LEU A CA  1 
ATOM   4605  C  C   . LEU A 1 626 ? 183.264 154.100 122.545 1.00 72.49  ? 619 LEU A C   1 
ATOM   4606  O  O   . LEU A 1 626 ? 182.342 153.798 121.780 1.00 72.49  ? 619 LEU A O   1 
ATOM   4607  C  CB  . LEU A 1 626 ? 184.384 152.114 123.564 1.00 72.49  ? 619 LEU A CB  1 
ATOM   4608  C  CG  . LEU A 1 626 ? 183.324 151.026 123.383 1.00 72.49  ? 619 LEU A CG  1 
ATOM   4609  C  CD1 . LEU A 1 626 ? 183.036 150.753 121.914 1.00 72.49  ? 619 LEU A CD1 1 
ATOM   4610  C  CD2 . LEU A 1 626 ? 183.762 149.753 124.089 1.00 72.49  ? 619 LEU A CD2 1 
ATOM   4611  N  N   . LEU A 1 627 ? 183.233 155.172 123.344 1.00 72.96  ? 620 LEU A N   1 
ATOM   4612  C  CA  . LEU A 1 627 ? 181.986 155.980 123.467 1.00 72.96  ? 620 LEU A CA  1 
ATOM   4613  C  C   . LEU A 1 627 ? 182.077 157.275 122.649 1.00 72.96  ? 620 LEU A C   1 
ATOM   4614  O  O   . LEU A 1 627 ? 181.021 157.734 122.175 1.00 72.96  ? 620 LEU A O   1 
ATOM   4615  C  CB  . LEU A 1 627 ? 181.745 156.286 124.949 1.00 72.96  ? 620 LEU A CB  1 
ATOM   4616  C  CG  . LEU A 1 627 ? 181.491 155.066 125.833 1.00 72.96  ? 620 LEU A CG  1 
ATOM   4617  C  CD1 . LEU A 1 627 ? 180.919 155.480 127.180 1.00 72.96  ? 620 LEU A CD1 1 
ATOM   4618  C  CD2 . LEU A 1 627 ? 180.563 154.079 125.141 1.00 72.96  ? 620 LEU A CD2 1 
ATOM   4619  N  N   . GLU A 1 628 ? 183.274 157.849 122.495 1.00 76.22  ? 621 GLU A N   1 
ATOM   4620  C  CA  . GLU A 1 628 ? 183.395 159.127 121.794 1.00 76.22  ? 621 GLU A CA  1 
ATOM   4621  C  C   . GLU A 1 628 ? 182.900 159.073 120.353 1.00 76.22  ? 621 GLU A C   1 
ATOM   4622  O  O   . GLU A 1 628 ? 182.150 159.981 119.951 1.00 76.22  ? 621 GLU A O   1 
ATOM   4623  C  CB  . GLU A 1 628 ? 184.844 159.621 121.878 1.00 76.22  ? 621 GLU A CB  1 
ATOM   4624  C  CG  . GLU A 1 628 ? 185.156 160.867 121.054 1.00 76.22  ? 621 GLU A CG  1 
ATOM   4625  C  CD  . GLU A 1 628 ? 185.525 160.550 119.616 1.00 76.22  ? 621 GLU A CD  1 
ATOM   4626  O  OE1 . GLU A 1 628 ? 185.996 159.424 119.356 1.00 76.22  ? 621 GLU A OE1 1 
ATOM   4627  O  OE2 . GLU A 1 628 ? 185.343 161.429 118.747 1.00 76.22  ? 621 GLU A OE2 1 
ATOM   4628  N  N   . PRO A 1 629 ? 183.264 158.069 119.517 1.00 74.16  ? 622 PRO A N   1 
ATOM   4629  C  CA  . PRO A 1 629 ? 182.824 158.107 118.113 1.00 74.16  ? 622 PRO A CA  1 
ATOM   4630  C  C   . PRO A 1 629 ? 181.315 158.014 117.952 1.00 74.16  ? 622 PRO A C   1 
ATOM   4631  O  O   . PRO A 1 629 ? 180.794 158.129 116.838 1.00 74.16  ? 622 PRO A O   1 
ATOM   4632  C  CB  . PRO A 1 629 ? 183.536 156.903 117.487 1.00 74.16  ? 622 PRO A CB  1 
ATOM   4633  C  CG  . PRO A 1 629 ? 183.743 155.969 118.603 1.00 74.16  ? 622 PRO A CG  1 
ATOM   4634  C  CD  . PRO A 1 629 ? 183.999 156.825 119.811 1.00 74.16  ? 622 PRO A CD  1 
ATOM   4635  N  N   . LEU A 1 630 ? 180.604 157.798 119.056 1.00 66.18  ? 623 LEU A N   1 
ATOM   4636  C  CA  . LEU A 1 630 ? 179.156 157.922 119.073 1.00 66.18  ? 623 LEU A CA  1 
ATOM   4637  C  C   . LEU A 1 630 ? 178.704 159.369 119.236 1.00 66.18  ? 623 LEU A C   1 
ATOM   4638  O  O   . LEU A 1 630 ? 177.517 159.658 119.054 1.00 66.18  ? 623 LEU A O   1 
ATOM   4639  C  CB  . LEU A 1 630 ? 178.570 157.061 120.199 1.00 66.18  ? 623 LEU A CB  1 
ATOM   4640  C  CG  . LEU A 1 630 ? 177.058 156.839 120.214 1.00 66.18  ? 623 LEU A CG  1 
ATOM   4641  C  CD1 . LEU A 1 630 ? 176.571 156.551 118.806 1.00 66.18  ? 623 LEU A CD1 1 
ATOM   4642  C  CD2 . LEU A 1 630 ? 176.681 155.714 121.161 1.00 66.18  ? 623 LEU A CD2 1 
ATOM   4643  N  N   . GLY A 1 631 ? 179.622 160.282 119.547 1.00 72.63  ? 624 GLY A N   1 
ATOM   4644  C  CA  . GLY A 1 631 ? 179.289 161.687 119.688 1.00 72.63  ? 624 GLY A CA  1 
ATOM   4645  C  C   . GLY A 1 631 ? 179.032 162.122 121.115 1.00 72.63  ? 624 GLY A C   1 
ATOM   4646  O  O   . GLY A 1 631 ? 178.008 162.749 121.402 1.00 72.63  ? 624 GLY A O   1 
ATOM   4647  N  N   . LEU A 1 632 ? 179.956 161.802 122.019 1.00 70.00  ? 625 LEU A N   1 
ATOM   4648  C  CA  . LEU A 1 632 ? 179.802 162.122 123.430 1.00 70.00  ? 625 LEU A CA  1 
ATOM   4649  C  C   . LEU A 1 632 ? 181.102 162.696 123.975 1.00 70.00  ? 625 LEU A C   1 
ATOM   4650  O  O   . LEU A 1 632 ? 182.161 162.601 123.350 1.00 70.00  ? 625 LEU A O   1 
ATOM   4651  C  CB  . LEU A 1 632 ? 179.409 160.890 124.252 1.00 70.00  ? 625 LEU A CB  1 
ATOM   4652  C  CG  . LEU A 1 632 ? 178.139 160.141 123.861 1.00 70.00  ? 625 LEU A CG  1 
ATOM   4653  C  CD1 . LEU A 1 632 ? 177.962 158.950 124.773 1.00 70.00  ? 625 LEU A CD1 1 
ATOM   4654  C  CD2 . LEU A 1 632 ? 176.935 161.056 123.936 1.00 70.00  ? 625 LEU A CD2 1 
ATOM   4655  N  N   . GLN A 1 633 ? 181.003 163.299 125.156 1.00 70.15  ? 626 GLN A N   1 
ATOM   4656  C  CA  . GLN A 1 633 ? 182.154 163.743 125.927 1.00 70.15  ? 626 GLN A CA  1 
ATOM   4657  C  C   . GLN A 1 633 ? 182.162 163.012 127.260 1.00 70.15  ? 626 GLN A C   1 
ATOM   4658  O  O   . GLN A 1 633 ? 181.125 162.901 127.922 1.00 70.15  ? 626 GLN A O   1 
ATOM   4659  C  CB  . GLN A 1 633 ? 182.128 165.257 126.159 1.00 70.15  ? 626 GLN A CB  1 
ATOM   4660  C  CG  . GLN A 1 633 ? 182.524 166.080 124.949 1.00 70.15  ? 626 GLN A CG  1 
ATOM   4661  C  CD  . GLN A 1 633 ? 181.387 166.252 123.965 1.00 70.15  ? 626 GLN A CD  1 
ATOM   4662  O  OE1 . GLN A 1 633 ? 180.367 166.865 124.279 1.00 70.15  ? 626 GLN A OE1 1 
ATOM   4663  N  NE2 . GLN A 1 633 ? 181.555 165.707 122.766 1.00 70.15  ? 626 GLN A NE2 1 
ATOM   4664  N  N   . CYS A 1 634 ? 183.330 162.515 127.655 1.00 72.75  ? 627 CYS A N   1 
ATOM   4665  C  CA  . CYS A 1 634 ? 183.469 161.705 128.856 1.00 72.75  ? 627 CYS A CA  1 
ATOM   4666  C  C   . CYS A 1 634 ? 184.277 162.460 129.900 1.00 72.75  ? 627 CYS A C   1 
ATOM   4667  O  O   . CYS A 1 634 ? 185.406 162.884 129.632 1.00 72.75  ? 627 CYS A O   1 
ATOM   4668  C  CB  . CYS A 1 634 ? 184.141 160.368 128.536 1.00 72.75  ? 627 CYS A CB  1 
ATOM   4669  S  SG  . CYS A 1 634 ? 183.532 159.576 127.033 1.00 72.75  ? 627 CYS A SG  1 
ATOM   4670  N  N   . THR A 1 635 ? 183.696 162.625 131.086 1.00 70.46  ? 628 THR A N   1 
ATOM   4671  C  CA  . THR A 1 635 ? 184.378 163.205 132.235 1.00 70.46  ? 628 THR A CA  1 
ATOM   4672  C  C   . THR A 1 635 ? 184.324 162.213 133.387 1.00 70.46  ? 628 THR A C   1 
ATOM   4673  O  O   . THR A 1 635 ? 183.243 161.739 133.751 1.00 70.46  ? 628 THR A O   1 
ATOM   4674  C  CB  . THR A 1 635 ? 183.744 164.534 132.659 1.00 70.46  ? 628 THR A CB  1 
ATOM   4675  O  OG1 . THR A 1 635 ? 182.581 164.277 133.456 1.00 70.46  ? 628 THR A OG1 1 
ATOM   4676  C  CG2 . THR A 1 635 ? 183.348 165.354 131.442 1.00 70.46  ? 628 THR A CG2 1 
ATOM   4677  N  N   . PHE A 1 636 ? 185.483 161.905 133.956 1.00 69.67  ? 629 PHE A N   1 
ATOM   4678  C  CA  . PHE A 1 636 ? 185.591 160.941 135.042 1.00 69.67  ? 629 PHE A CA  1 
ATOM   4679  C  C   . PHE A 1 636 ? 185.639 161.677 136.373 1.00 69.67  ? 629 PHE A C   1 
ATOM   4680  O  O   . PHE A 1 636 ? 186.428 162.612 136.542 1.00 69.67  ? 629 PHE A O   1 
ATOM   4681  C  CB  . PHE A 1 636 ? 186.837 160.069 134.876 1.00 69.67  ? 629 PHE A CB  1 
ATOM   4682  C  CG  . PHE A 1 636 ? 186.825 159.221 133.636 1.00 69.67  ? 629 PHE A CG  1 
ATOM   4683  C  CD1 . PHE A 1 636 ? 187.317 159.714 132.440 1.00 69.67  ? 629 PHE A CD1 1 
ATOM   4684  C  CD2 . PHE A 1 636 ? 186.328 157.932 133.667 1.00 69.67  ? 629 PHE A CD2 1 
ATOM   4685  C  CE1 . PHE A 1 636 ? 187.308 158.937 131.299 1.00 69.67  ? 629 PHE A CE1 1 
ATOM   4686  C  CE2 . PHE A 1 636 ? 186.317 157.151 132.529 1.00 69.67  ? 629 PHE A CE2 1 
ATOM   4687  C  CZ  . PHE A 1 636 ? 186.807 157.655 131.344 1.00 69.67  ? 629 PHE A CZ  1 
ATOM   4688  N  N   . ILE A 1 637 ? 184.747 161.249 137.275 1.00 66.24  ? 630 ILE A N   1 
ATOM   4689  C  CA  . ILE A 1 637 ? 184.664 161.847 138.636 1.00 66.24  ? 630 ILE A CA  1 
ATOM   4690  C  C   . ILE A 1 637 ? 185.171 160.797 139.624 1.00 66.24  ? 630 ILE A C   1 
ATOM   4691  O  O   . ILE A 1 637 ? 184.910 159.601 139.395 1.00 66.24  ? 630 ILE A O   1 
ATOM   4692  C  CB  . ILE A 1 637 ? 183.209 162.247 138.949 1.00 66.24  ? 630 ILE A CB  1 
ATOM   4693  C  CG1 . ILE A 1 637 ? 182.585 163.061 137.812 1.00 66.24  ? 630 ILE A CG1 1 
ATOM   4694  C  CG2 . ILE A 1 637 ? 183.117 162.974 140.282 1.00 66.24  ? 630 ILE A CG2 1 
ATOM   4695  C  CD1 . ILE A 1 637 ? 181.123 163.375 138.019 1.00 66.24  ? 630 ILE A CD1 1 
ATOM   4696  N  N   . ASN A 1 638 ? 185.862 161.227 140.678 1.00 73.54  ? 631 ASN A N   1 
ATOM   4697  C  CA  . ASN A 1 638 ? 186.400 160.314 141.677 1.00 73.54  ? 631 ASN A CA  1 
ATOM   4698  C  C   . ASN A 1 638 ? 185.482 160.275 142.893 1.00 73.54  ? 631 ASN A C   1 
ATOM   4699  O  O   . ASN A 1 638 ? 185.199 161.314 143.500 1.00 73.54  ? 631 ASN A O   1 
ATOM   4700  C  CB  . ASN A 1 638 ? 187.813 160.735 142.079 1.00 73.54  ? 631 ASN A CB  1 
ATOM   4701  C  CG  . ASN A 1 638 ? 187.926 162.223 142.337 1.00 73.54  ? 631 ASN A CG  1 
ATOM   4702  O  OD1 . ASN A 1 638 ? 187.153 163.018 141.801 1.00 73.54  ? 631 ASN A OD1 1 
ATOM   4703  N  ND2 . ASN A 1 638 ? 188.894 162.610 143.158 1.00 73.54  ? 631 ASN A ND2 1 
ATOM   4704  N  N   . ASP A 1 639 ? 185.019 159.073 143.244 1.00 78.29  ? 632 ASP A N   1 
ATOM   4705  C  CA  . ASP A 1 639 ? 184.201 158.865 144.432 1.00 78.29  ? 632 ASP A CA  1 
ATOM   4706  C  C   . ASP A 1 639 ? 184.614 157.596 145.168 1.00 78.29  ? 632 ASP A C   1 
ATOM   4707  O  O   . ASP A 1 639 ? 183.773 156.924 145.776 1.00 78.29  ? 632 ASP A O   1 
ATOM   4708  C  CB  . ASP A 1 639 ? 182.715 158.805 144.076 1.00 78.29  ? 632 ASP A CB  1 
ATOM   4709  C  CG  . ASP A 1 639 ? 182.419 157.804 142.977 1.00 78.29  ? 632 ASP A CG  1 
ATOM   4710  O  OD1 . ASP A 1 639 ? 182.551 156.588 143.223 1.00 78.29  ? 632 ASP A OD1 1 
ATOM   4711  O  OD2 . ASP A 1 639 ? 182.052 158.235 141.866 1.00 78.29  ? 632 ASP A OD2 1 
ATOM   4712  N  N   . PHE A 1 640 ? 185.902 157.250 145.114 1.00 86.22  ? 633 PHE A N   1 
ATOM   4713  C  CA  . PHE A 1 640 ? 186.365 155.994 145.695 1.00 86.22  ? 633 PHE A CA  1 
ATOM   4714  C  C   . PHE A 1 640 ? 186.231 156.000 147.214 1.00 86.22  ? 633 PHE A C   1 
ATOM   4715  O  O   . PHE A 1 640 ? 185.666 155.069 147.800 1.00 86.22  ? 633 PHE A O   1 
ATOM   4716  C  CB  . PHE A 1 640 ? 187.814 155.739 145.276 1.00 86.22  ? 633 PHE A CB  1 
ATOM   4717  C  CG  . PHE A 1 640 ? 188.225 154.295 145.335 1.00 86.22  ? 633 PHE A CG  1 
ATOM   4718  C  CD1 . PHE A 1 640 ? 188.106 153.565 146.506 1.00 86.22  ? 633 PHE A CD1 1 
ATOM   4719  C  CD2 . PHE A 1 640 ? 188.726 153.667 144.211 1.00 86.22  ? 633 PHE A CD2 1 
ATOM   4720  C  CE1 . PHE A 1 640 ? 188.484 152.240 146.554 1.00 86.22  ? 633 PHE A CE1 1 
ATOM   4721  C  CE2 . PHE A 1 640 ? 189.104 152.343 144.253 1.00 86.22  ? 633 PHE A CE2 1 
ATOM   4722  C  CZ  . PHE A 1 640 ? 188.983 151.628 145.426 1.00 86.22  ? 633 PHE A CZ  1 
ATOM   4723  N  N   . PHE A 1 641 ? 186.742 157.040 147.870 1.00 92.29  ? 634 PHE A N   1 
ATOM   4724  C  CA  . PHE A 1 641 ? 186.734 157.084 149.327 1.00 92.29  ? 634 PHE A CA  1 
ATOM   4725  C  C   . PHE A 1 641 ? 185.384 157.471 149.912 1.00 92.29  ? 634 PHE A C   1 
ATOM   4726  O  O   . PHE A 1 641 ? 185.160 157.243 151.105 1.00 92.29  ? 634 PHE A O   1 
ATOM   4727  C  CB  . PHE A 1 641 ? 187.801 158.059 149.831 1.00 92.29  ? 634 PHE A CB  1 
ATOM   4728  C  CG  . PHE A 1 641 ? 189.198 157.517 149.763 1.00 92.29  ? 634 PHE A CG  1 
ATOM   4729  C  CD1 . PHE A 1 641 ? 189.495 156.267 150.278 1.00 92.29  ? 634 PHE A CD1 1 
ATOM   4730  C  CD2 . PHE A 1 641 ? 190.217 158.261 149.193 1.00 92.29  ? 634 PHE A CD2 1 
ATOM   4731  C  CE1 . PHE A 1 641 ? 190.780 155.765 150.221 1.00 92.29  ? 634 PHE A CE1 1 
ATOM   4732  C  CE2 . PHE A 1 641 ? 191.505 157.765 149.133 1.00 92.29  ? 634 PHE A CE2 1 
ATOM   4733  C  CZ  . PHE A 1 641 ? 191.786 156.516 149.648 1.00 92.29  ? 634 PHE A CZ  1 
ATOM   4734  N  N   . THR A 1 642 ? 184.483 158.042 149.115 1.00 83.55  ? 635 THR A N   1 
ATOM   4735  C  CA  . THR A 1 642 ? 183.205 158.522 149.622 1.00 83.55  ? 635 THR A CA  1 
ATOM   4736  C  C   . THR A 1 642 ? 182.019 157.658 149.229 1.00 83.55  ? 635 THR A C   1 
ATOM   4737  O  O   . THR A 1 642 ? 181.035 157.619 149.968 1.00 83.55  ? 635 THR A O   1 
ATOM   4738  C  CB  . THR A 1 642 ? 182.946 159.956 149.143 1.00 83.55  ? 635 THR A CB  1 
ATOM   4739  O  OG1 . THR A 1 642 ? 182.278 159.923 147.876 1.00 83.55  ? 635 THR A OG1 1 
ATOM   4740  C  CG2 . THR A 1 642 ? 184.256 160.716 149.000 1.00 83.55  ? 635 THR A CG2 1 
ATOM   4741  N  N   . TYR A 1 643 ? 182.081 156.969 148.092 1.00 77.20  ? 636 TYR A N   1 
ATOM   4742  C  CA  . TYR A 1 643 ? 180.975 156.135 147.638 1.00 77.20  ? 636 TYR A CA  1 
ATOM   4743  C  C   . TYR A 1 643 ? 181.357 154.671 147.496 1.00 77.20  ? 636 TYR A C   1 
ATOM   4744  O  O   . TYR A 1 643 ? 180.648 153.797 148.013 1.00 77.20  ? 636 TYR A O   1 
ATOM   4745  C  CB  . TYR A 1 643 ? 180.433 156.667 146.303 1.00 77.20  ? 636 TYR A CB  1 
ATOM   4746  C  CG  . TYR A 1 643 ? 179.295 157.646 146.462 1.00 77.20  ? 636 TYR A CG  1 
ATOM   4747  C  CD1 . TYR A 1 643 ? 179.523 158.932 146.926 1.00 77.20  ? 636 TYR A CD1 1 
ATOM   4748  C  CD2 . TYR A 1 643 ? 177.993 157.281 146.155 1.00 77.20  ? 636 TYR A CD2 1 
ATOM   4749  C  CE1 . TYR A 1 643 ? 178.488 159.831 147.075 1.00 77.20  ? 636 TYR A CE1 1 
ATOM   4750  C  CE2 . TYR A 1 643 ? 176.952 158.172 146.301 1.00 77.20  ? 636 TYR A CE2 1 
ATOM   4751  C  CZ  . TYR A 1 643 ? 177.205 159.446 146.762 1.00 77.20  ? 636 TYR A CZ  1 
ATOM   4752  O  OH  . TYR A 1 643 ? 176.170 160.338 146.910 1.00 77.20  ? 636 TYR A OH  1 
ATOM   4753  N  N   . HIS A 1 644 ? 182.472 154.377 146.821 1.00 75.06  ? 637 HIS A N   1 
ATOM   4754  C  CA  . HIS A 1 644 ? 182.832 152.989 146.549 1.00 75.06  ? 637 HIS A CA  1 
ATOM   4755  C  C   . HIS A 1 644 ? 183.030 152.202 147.837 1.00 75.06  ? 637 HIS A C   1 
ATOM   4756  O  O   . HIS A 1 644 ? 182.699 151.012 147.900 1.00 75.06  ? 637 HIS A O   1 
ATOM   4757  C  CB  . HIS A 1 644 ? 184.094 152.932 145.694 1.00 75.06  ? 637 HIS A CB  1 
ATOM   4758  C  CG  . HIS A 1 644 ? 184.394 151.571 145.150 1.00 75.06  ? 637 HIS A CG  1 
ATOM   4759  N  ND1 . HIS A 1 644 ? 183.770 150.429 145.605 1.00 75.06  ? 637 HIS A ND1 1 
ATOM   4760  C  CD2 . HIS A 1 644 ? 185.264 151.168 144.196 1.00 75.06  ? 637 HIS A CD2 1 
ATOM   4761  C  CE1 . HIS A 1 644 ? 184.238 149.383 144.949 1.00 75.06  ? 637 HIS A CE1 1 
ATOM   4762  N  NE2 . HIS A 1 644 ? 185.145 149.804 144.088 1.00 75.06  ? 637 HIS A NE2 1 
ATOM   4763  N  N   . ILE A 1 645 ? 183.577 152.845 148.871 1.00 79.81  ? 638 ILE A N   1 
ATOM   4764  C  CA  . ILE A 1 645 ? 183.785 152.160 150.141 1.00 79.81  ? 638 ILE A CA  1 
ATOM   4765  C  C   . ILE A 1 645 ? 182.463 151.649 150.695 1.00 79.81  ? 638 ILE A C   1 
ATOM   4766  O  O   . ILE A 1 645 ? 182.407 150.568 151.294 1.00 79.81  ? 638 ILE A O   1 
ATOM   4767  C  CB  . ILE A 1 645 ? 184.509 153.095 151.132 1.00 79.81  ? 638 ILE A CB  1 
ATOM   4768  C  CG1 . ILE A 1 645 ? 186.017 153.066 150.876 1.00 79.81  ? 638 ILE A CG1 1 
ATOM   4769  C  CG2 . ILE A 1 645 ? 184.212 152.712 152.573 1.00 79.81  ? 638 ILE A CG2 1 
ATOM   4770  C  CD1 . ILE A 1 645 ? 186.611 151.674 150.910 1.00 79.81  ? 638 ILE A CD1 1 
ATOM   4771  N  N   . ARG A 1 646 ? 181.377 152.388 150.477 1.00 78.52  ? 639 ARG A N   1 
ATOM   4772  C  CA  . ARG A 1 646 ? 180.053 151.968 150.916 1.00 78.52  ? 639 ARG A CA  1 
ATOM   4773  C  C   . ARG A 1 646 ? 179.255 151.316 149.789 1.00 78.52  ? 639 ARG A C   1 
ATOM   4774  O  O   . ARG A 1 646 ? 178.023 151.318 149.815 1.00 78.52  ? 639 ARG A O   1 
ATOM   4775  C  CB  . ARG A 1 646 ? 179.285 153.146 151.515 1.00 78.52  ? 639 ARG A CB  1 
ATOM   4776  C  CG  . ARG A 1 646 ? 179.889 153.677 152.809 1.00 78.52  ? 639 ARG A CG  1 
ATOM   4777  C  CD  . ARG A 1 646 ? 179.409 155.085 153.124 1.00 78.52  ? 639 ARG A CD  1 
ATOM   4778  N  NE  . ARG A 1 646 ? 180.265 156.108 152.537 1.00 78.52  ? 639 ARG A NE  1 
ATOM   4779  C  CZ  . ARG A 1 646 ? 181.205 156.768 153.200 1.00 78.52  ? 639 ARG A CZ  1 
ATOM   4780  N  NH1 . ARG A 1 646 ? 181.437 156.537 154.482 1.00 78.52  ? 639 ARG A NH1 1 
ATOM   4781  N  NH2 . ARG A 1 646 ? 181.928 157.684 152.563 1.00 78.52  ? 639 ARG A NH2 1 
ATOM   4782  N  N   . HIS A 1 647 ? 179.949 150.747 148.801 1.00 80.05  ? 640 HIS A N   1 
ATOM   4783  C  CA  . HIS A 1 647 ? 179.337 149.969 147.722 1.00 80.05  ? 640 HIS A CA  1 
ATOM   4784  C  C   . HIS A 1 647 ? 178.330 150.812 146.933 1.00 80.05  ? 640 HIS A C   1 
ATOM   4785  O  O   . HIS A 1 647 ? 177.128 150.543 146.905 1.00 80.05  ? 640 HIS A O   1 
ATOM   4786  C  CB  . HIS A 1 647 ? 178.671 148.701 148.272 1.00 80.05  ? 640 HIS A CB  1 
ATOM   4787  C  CG  . HIS A 1 647 ? 179.573 147.859 149.118 1.00 80.05  ? 640 HIS A CG  1 
ATOM   4788  N  ND1 . HIS A 1 647 ? 179.281 147.541 150.427 1.00 80.05  ? 640 HIS A ND1 1 
ATOM   4789  C  CD2 . HIS A 1 647 ? 180.758 147.265 148.842 1.00 80.05  ? 640 HIS A CD2 1 
ATOM   4790  C  CE1 . HIS A 1 647 ? 180.248 146.789 150.921 1.00 80.05  ? 640 HIS A CE1 1 
ATOM   4791  N  NE2 . HIS A 1 647 ? 181.157 146.607 149.980 1.00 80.05  ? 640 HIS A NE2 1 
ATOM   4792  N  N   . GLY A 1 648 ? 178.860 151.845 146.284 1.00 72.98  ? 641 GLY A N   1 
ATOM   4793  C  CA  . GLY A 1 648 ? 178.021 152.725 145.493 1.00 72.98  ? 641 GLY A CA  1 
ATOM   4794  C  C   . GLY A 1 648 ? 178.797 153.401 144.388 1.00 72.98  ? 641 GLY A C   1 
ATOM   4795  O  O   . GLY A 1 648 ? 180.030 153.367 144.353 1.00 72.98  ? 641 GLY A O   1 
ATOM   4796  N  N   . GLU A 1 649 ? 178.049 154.012 143.468 1.00 66.97  ? 642 GLU A N   1 
ATOM   4797  C  CA  . GLU A 1 649 ? 178.635 154.774 142.371 1.00 66.97  ? 642 GLU A CA  1 
ATOM   4798  C  C   . GLU A 1 649 ? 177.907 156.103 142.206 1.00 66.97  ? 642 GLU A C   1 
ATOM   4799  O  O   . GLU A 1 649 ? 177.053 156.448 143.028 1.00 66.97  ? 642 GLU A O   1 
ATOM   4800  C  CB  . GLU A 1 649 ? 178.595 153.970 141.071 1.00 66.97  ? 642 GLU A CB  1 
ATOM   4801  C  CG  . GLU A 1 649 ? 179.149 152.554 141.189 1.00 66.97  ? 642 GLU A CG  1 
ATOM   4802  C  CD  . GLU A 1 649 ? 180.661 152.519 141.313 1.00 66.97  ? 642 GLU A CD  1 
ATOM   4803  O  OE1 . GLU A 1 649 ? 181.302 153.577 141.145 1.00 66.97  ? 642 GLU A OE1 1 
ATOM   4804  O  OE2 . GLU A 1 649 ? 181.210 151.430 141.579 1.00 66.97  ? 642 GLU A OE2 1 
ATOM   4805  N  N   . VAL A 1 650 ? 178.278 156.865 141.173 1.00 63.76  ? 643 VAL A N   1 
ATOM   4806  C  CA  . VAL A 1 650 ? 177.702 158.233 140.993 1.00 63.76  ? 643 VAL A CA  1 
ATOM   4807  C  C   . VAL A 1 650 ? 176.193 158.151 140.756 1.00 63.76  ? 643 VAL A C   1 
ATOM   4808  O  O   . VAL A 1 650 ? 175.452 158.865 141.457 1.00 63.76  ? 643 VAL A O   1 
ATOM   4809  C  CB  . VAL A 1 650 ? 178.410 158.986 139.848 1.00 63.76  ? 643 VAL A CB  1 
ATOM   4810  C  CG1 . VAL A 1 650 ? 179.889 159.145 140.139 1.00 63.76  ? 643 VAL A CG1 1 
ATOM   4811  C  CG2 . VAL A 1 650 ? 178.219 158.315 138.496 1.00 63.76  ? 643 VAL A CG2 1 
ATOM   4812  N  N   . HIS A 1 651 ? 175.756 157.312 139.817 1.00 60.32  ? 644 HIS A N   1 
ATOM   4813  C  CA  . HIS A 1 651 ? 174.339 157.275 139.473 1.00 60.32  ? 644 HIS A CA  1 
ATOM   4814  C  C   . HIS A 1 651 ? 173.495 156.760 140.630 1.00 60.32  ? 644 HIS A C   1 
ATOM   4815  O  O   . HIS A 1 651 ? 172.309 157.095 140.728 1.00 60.32  ? 644 HIS A O   1 
ATOM   4816  C  CB  . HIS A 1 651 ? 174.116 156.420 138.227 1.00 60.32  ? 644 HIS A CB  1 
ATOM   4817  C  CG  . HIS A 1 651 ? 172.674 156.169 137.918 1.00 60.32  ? 644 HIS A CG  1 
ATOM   4818  N  ND1 . HIS A 1 651 ? 172.140 154.902 137.832 1.00 60.32  ? 644 HIS A ND1 1 
ATOM   4819  C  CD2 . HIS A 1 651 ? 171.650 157.025 137.688 1.00 60.32  ? 644 HIS A CD2 1 
ATOM   4820  C  CE1 . HIS A 1 651 ? 170.851 154.988 137.555 1.00 60.32  ? 644 HIS A CE1 1 
ATOM   4821  N  NE2 . HIS A 1 651 ? 170.529 156.265 137.463 1.00 60.32  ? 644 HIS A NE2 1 
ATOM   4822  N  N   . CYS A 1 652 ? 174.083 155.957 141.516 1.00 61.84  ? 645 CYS A N   1 
ATOM   4823  C  CA  . CYS A 1 652 ? 173.362 155.491 142.691 1.00 61.84  ? 645 CYS A CA  1 
ATOM   4824  C  C   . CYS A 1 652 ? 173.211 156.570 143.752 1.00 61.84  ? 645 CYS A C   1 
ATOM   4825  O  O   . CYS A 1 652 ? 172.448 156.373 144.703 1.00 61.84  ? 645 CYS A O   1 
ATOM   4826  C  CB  . CYS A 1 652 ? 174.066 154.272 143.291 1.00 30.00  ? 645 CYS A CB  1 
ATOM   4827  S  SG  . CYS A 1 652 ? 174.086 152.819 142.217 1.00 30.00  ? 645 CYS A SG  1 
ATOM   4828  N  N   . GLY A 1 653 ? 173.909 157.695 143.619 1.00 63.77  ? 646 GLY A N   1 
ATOM   4829  C  CA  . GLY A 1 653 ? 173.841 158.744 144.616 1.00 63.77  ? 646 GLY A CA  1 
ATOM   4830  C  C   . GLY A 1 653 ? 173.200 160.028 144.134 1.00 63.77  ? 646 GLY A C   1 
ATOM   4831  O  O   . GLY A 1 653 ? 173.078 160.988 144.899 1.00 63.77  ? 646 GLY A O   1 
ATOM   4832  N  N   . THR A 1 654 ? 172.794 160.066 142.866 1.00 57.09  ? 647 THR A N   1 
ATOM   4833  C  CA  . THR A 1 654 ? 172.152 161.239 142.290 1.00 57.09  ? 647 THR A CA  1 
ATOM   4834  C  C   . THR A 1 654 ? 170.923 160.811 141.502 1.00 57.09  ? 647 THR A C   1 
ATOM   4835  O  O   . THR A 1 654 ? 170.831 159.680 141.019 1.00 57.09  ? 647 THR A O   1 
ATOM   4836  C  CB  . THR A 1 654 ? 173.094 162.029 141.369 1.00 57.09  ? 647 THR A CB  1 
ATOM   4837  O  OG1 . THR A 1 654 ? 173.005 161.507 140.038 1.00 57.09  ? 647 THR A OG1 1 
ATOM   4838  C  CG2 . THR A 1 654 ? 174.536 161.954 141.849 1.00 57.09  ? 647 THR A CG2 1 
ATOM   4839  N  N   . ASN A 1 655 ? 169.975 161.736 141.370 1.00 48.49  ? 648 ASN A N   1 
ATOM   4840  C  CA  . ASN A 1 655 ? 168.759 161.513 140.604 1.00 48.49  ? 648 ASN A CA  1 
ATOM   4841  C  C   . ASN A 1 655 ? 168.558 162.650 139.616 1.00 48.49  ? 648 ASN A C   1 
ATOM   4842  O  O   . ASN A 1 655 ? 169.016 163.774 139.837 1.00 48.49  ? 648 ASN A O   1 
ATOM   4843  C  CB  . ASN A 1 655 ? 167.531 161.395 141.504 1.00 48.49  ? 648 ASN A CB  1 
ATOM   4844  C  CG  . ASN A 1 655 ? 166.547 160.366 141.002 1.00 48.49  ? 648 ASN A CG  1 
ATOM   4845  O  OD1 . ASN A 1 655 ? 166.456 160.115 139.802 1.00 48.49  ? 648 ASN A OD1 1 
ATOM   4846  N  ND2 . ASN A 1 655 ? 165.804 159.763 141.917 1.00 48.49  ? 648 ASN A ND2 1 
ATOM   4847  N  N   . VAL A 1 656 ? 167.868 162.345 138.519 1.00 39.84  ? 649 VAL A N   1 
ATOM   4848  C  CA  . VAL A 1 656 ? 167.647 163.289 137.431 1.00 39.84  ? 649 VAL A CA  1 
ATOM   4849  C  C   . VAL A 1 656 ? 166.172 163.277 137.059 1.00 39.84  ? 649 VAL A C   1 
ATOM   4850  O  O   . VAL A 1 656 ? 165.553 162.212 136.979 1.00 39.84  ? 649 VAL A O   1 
ATOM   4851  C  CB  . VAL A 1 656 ? 168.510 162.946 136.199 1.00 39.84  ? 649 VAL A CB  1 
ATOM   4852  C  CG1 . VAL A 1 656 ? 168.356 164.005 135.125 1.00 39.84  ? 649 VAL A CG1 1 
ATOM   4853  C  CG2 . VAL A 1 656 ? 169.965 162.790 136.588 1.00 39.84  ? 649 VAL A CG2 1 
ATOM   4854  N  N   . ARG A 1 657 ? 165.650 164.486 136.807 1.00 34.58  ? 650 ARG A N   1 
ATOM   4855  C  CA  . ARG A 1 657 ? 164.268 164.635 136.294 1.00 34.58  ? 650 ARG A CA  1 
ATOM   4856  C  C   . ARG A 1 657 ? 164.413 164.850 134.782 1.00 34.58  ? 650 ARG A C   1 
ATOM   4857  O  O   . ARG A 1 657 ? 165.374 165.545 134.384 1.00 34.58  ? 650 ARG A O   1 
ATOM   4858  C  CB  . ARG A 1 657 ? 163.578 165.809 136.995 1.00 34.58  ? 650 ARG A CB  1 
ATOM   4859  C  CG  . ARG A 1 657 ? 162.123 166.024 136.605 1.00 34.58  ? 650 ARG A CG  1 
ATOM   4860  C  CD  . ARG A 1 657 ? 161.955 167.240 135.710 1.00 34.58  ? 650 ARG A CD  1 
ATOM   4861  N  NE  . ARG A 1 657 ? 162.504 168.455 136.322 1.00 34.58  ? 650 ARG A NE  1 
ATOM   4862  C  CZ  . ARG A 1 657 ? 162.076 169.683 136.060 1.00 34.58  ? 650 ARG A CZ  1 
ATOM   4863  N  NH1 . ARG A 1 657 ? 160.925 169.861 135.439 1.00 34.58  ? 650 ARG A NH1 1 
ATOM   4864  N  NH2 . ARG A 1 657 ? 162.802 170.730 136.412 1.00 34.58  ? 650 ARG A NH2 1 
ATOM   4865  N  N   . ARG A 1 658 ? 163.503 164.309 133.974 1.00 33.75  ? 651 ARG A N   1 
ATOM   4866  C  CA  . ARG A 1 658 ? 163.623 164.349 132.527 1.00 33.75  ? 651 ARG A CA  1 
ATOM   4867  C  C   . ARG A 1 658 ? 162.307 164.767 131.891 1.00 33.75  ? 651 ARG A C   1 
ATOM   4868  O  O   . ARG A 1 658 ? 161.229 164.550 132.451 1.00 33.75  ? 651 ARG A O   1 
ATOM   4869  C  CB  . ARG A 1 658 ? 164.075 162.992 131.988 1.00 33.75  ? 651 ARG A CB  1 
ATOM   4870  C  CG  . ARG A 1 658 ? 165.578 162.840 132.021 1.00 33.75  ? 651 ARG A CG  1 
ATOM   4871  C  CD  . ARG A 1 658 ? 166.020 161.400 132.013 1.00 33.75  ? 651 ARG A CD  1 
ATOM   4872  N  NE  . ARG A 1 658 ? 167.406 161.301 131.576 1.00 33.75  ? 651 ARG A NE  1 
ATOM   4873  C  CZ  . ARG A 1 658 ? 168.426 161.035 132.379 1.00 33.75  ? 651 ARG A CZ  1 
ATOM   4874  N  NH1 . ARG A 1 658 ? 168.250 160.814 133.670 1.00 33.75  ? 651 ARG A NH1 1 
ATOM   4875  N  NH2 . ARG A 1 658 ? 169.655 160.996 131.874 1.00 33.75  ? 651 ARG A NH2 1 
ATOM   4876  N  N   . LYS A 1 659 ? 162.412 165.373 130.713 1.00 29.58  ? 652 LYS A N   1 
ATOM   4877  C  CA  . LYS A 1 659 ? 161.237 165.885 130.027 1.00 29.58  ? 652 LYS A CA  1 
ATOM   4878  C  C   . LYS A 1 659 ? 160.315 164.735 129.624 1.00 29.58  ? 652 LYS A C   1 
ATOM   4879  O  O   . LYS A 1 659 ? 160.786 163.696 129.153 1.00 29.58  ? 652 LYS A O   1 
ATOM   4880  C  CB  . LYS A 1 659 ? 161.645 166.686 128.791 1.00 29.58  ? 652 LYS A CB  1 
ATOM   4881  C  CG  . LYS A 1 659 ? 160.474 167.119 127.922 1.00 29.58  ? 652 LYS A CG  1 
ATOM   4882  C  CD  . LYS A 1 659 ? 160.931 167.633 126.573 1.00 29.58  ? 652 LYS A CD  1 
ATOM   4883  C  CE  . LYS A 1 659 ? 159.752 167.801 125.629 1.00 29.58  ? 652 LYS A CE  1 
ATOM   4884  N  NZ  . LYS A 1 659 ? 160.190 168.101 124.238 1.00 29.58  ? 652 LYS A NZ  1 
ATOM   4885  N  N   . PRO A 1 660 ? 159.003 164.888 129.800 1.00 25.82  ? 653 PRO A N   1 
ATOM   4886  C  CA  . PRO A 1 660 ? 158.078 163.825 129.402 1.00 25.82  ? 653 PRO A CA  1 
ATOM   4887  C  C   . PRO A 1 660 ? 158.114 163.571 127.903 1.00 25.82  ? 653 PRO A C   1 
ATOM   4888  O  O   . PRO A 1 660 ? 158.548 164.406 127.108 1.00 25.82  ? 653 PRO A O   1 
ATOM   4889  C  CB  . PRO A 1 660 ? 156.713 164.364 129.842 1.00 25.82  ? 653 PRO A CB  1 
ATOM   4890  C  CG  . PRO A 1 660 ? 157.030 165.305 130.945 1.00 25.82  ? 653 PRO A CG  1 
ATOM   4891  C  CD  . PRO A 1 660 ? 158.318 165.954 130.547 1.00 25.82  ? 653 PRO A CD  1 
ATOM   4892  N  N   . PHE A 1 661 ? 157.656 162.379 127.528 1.00 28.36  ? 654 PHE A N   1 
ATOM   4893  C  CA  . PHE A 1 661 ? 157.611 161.981 126.130 1.00 28.36  ? 654 PHE A CA  1 
ATOM   4894  C  C   . PHE A 1 661 ? 156.683 162.888 125.334 1.00 28.36  ? 654 PHE A C   1 
ATOM   4895  O  O   . PHE A 1 661 ? 155.666 163.373 125.836 1.00 28.36  ? 654 PHE A O   1 
ATOM   4896  C  CB  . PHE A 1 661 ? 157.130 160.536 126.007 1.00 28.36  ? 654 PHE A CB  1 
ATOM   4897  C  CG  . PHE A 1 661 ? 158.222 159.518 126.102 1.00 28.36  ? 654 PHE A CG  1 
ATOM   4898  C  CD1 . PHE A 1 661 ? 159.191 159.434 125.123 1.00 28.36  ? 654 PHE A CD1 1 
ATOM   4899  C  CD2 . PHE A 1 661 ? 158.274 158.639 127.167 1.00 28.36  ? 654 PHE A CD2 1 
ATOM   4900  C  CE1 . PHE A 1 661 ? 160.192 158.494 125.206 1.00 28.36  ? 654 PHE A CE1 1 
ATOM   4901  C  CE2 . PHE A 1 661 ? 159.271 157.698 127.253 1.00 28.36  ? 654 PHE A CE2 1 
ATOM   4902  C  CZ  . PHE A 1 661 ? 160.231 157.625 126.272 1.00 28.36  ? 654 PHE A CZ  1 
ATOM   4903  N  N   . SER A 1 662 ? 157.047 163.120 124.073 1.00 32.68  ? 655 SER A N   1 
ATOM   4904  C  CA  . SER A 1 662 ? 156.148 163.816 123.163 1.00 32.68  ? 655 SER A CA  1 
ATOM   4905  C  C   . SER A 1 662 ? 155.025 162.909 122.683 1.00 32.68  ? 655 SER A C   1 
ATOM   4906  O  O   . SER A 1 662 ? 153.944 163.398 122.337 1.00 32.68  ? 655 SER A O   1 
ATOM   4907  C  CB  . SER A 1 662 ? 156.928 164.367 121.970 1.00 32.68  ? 655 SER A CB  1 
ATOM   4908  O  OG  . SER A 1 662 ? 157.740 165.461 122.358 1.00 32.68  ? 655 SER A OG  1 
ATOM   4909  N  N   . PHE A 1 663 ? 155.258 161.600 122.656 1.00 31.45  ? 656 PHE A N   1 
ATOM   4910  C  CA  . PHE A 1 663 ? 154.234 160.657 122.229 1.00 31.45  ? 656 PHE A CA  1 
ATOM   4911  C  C   . PHE A 1 663 ? 153.181 160.491 123.318 1.00 31.45  ? 656 PHE A C   1 
ATOM   4912  O  O   . PHE A 1 663 ? 153.507 160.222 124.478 1.00 31.45  ? 656 PHE A O   1 
ATOM   4913  C  CB  . PHE A 1 663 ? 154.871 159.311 121.892 1.00 31.45  ? 656 PHE A CB  1 
ATOM   4914  C  CG  . PHE A 1 663 ? 153.905 158.297 121.352 1.00 31.45  ? 656 PHE A CG  1 
ATOM   4915  C  CD1 . PHE A 1 663 ? 153.298 157.382 122.193 1.00 31.45  ? 656 PHE A CD1 1 
ATOM   4916  C  CD2 . PHE A 1 663 ? 153.608 158.256 120.003 1.00 31.45  ? 656 PHE A CD2 1 
ATOM   4917  C  CE1 . PHE A 1 663 ? 152.415 156.448 121.698 1.00 31.45  ? 656 PHE A CE1 1 
ATOM   4918  C  CE2 . PHE A 1 663 ? 152.723 157.323 119.504 1.00 31.45  ? 656 PHE A CE2 1 
ATOM   4919  C  CZ  . PHE A 1 663 ? 152.126 156.420 120.353 1.00 31.45  ? 656 PHE A CZ  1 
ATOM   4920  N  N   . LYS A 1 664 ? 151.916 160.643 122.940 1.00 32.29  ? 657 LYS A N   1 
ATOM   4921  C  CA  . LYS A 1 664 ? 150.818 160.548 123.890 1.00 32.29  ? 657 LYS A CA  1 
ATOM   4922  C  C   . LYS A 1 664 ? 150.536 159.088 124.223 1.00 32.29  ? 657 LYS A C   1 
ATOM   4923  O  O   . LYS A 1 664 ? 150.341 158.266 123.322 1.00 32.29  ? 657 LYS A O   1 
ATOM   4924  C  CB  . LYS A 1 664 ? 149.570 161.207 123.313 1.00 32.29  ? 657 LYS A CB  1 
ATOM   4925  C  CG  . LYS A 1 664 ? 149.806 162.574 122.689 1.00 32.29  ? 657 LYS A CG  1 
ATOM   4926  C  CD  . LYS A 1 664 ? 150.374 163.568 123.687 1.00 32.29  ? 657 LYS A CD  1 
ATOM   4927  C  CE  . LYS A 1 664 ? 150.494 164.955 123.072 1.00 32.29  ? 657 LYS A CE  1 
ATOM   4928  N  NZ  . LYS A 1 664 ? 151.230 165.899 123.956 1.00 32.29  ? 657 LYS A NZ  1 
ATOM   4929  N  N   . TRP A 1 665 ? 150.481 158.774 125.520 1.00 28.43  ? 658 TRP A N   1 
ATOM   4930  C  CA  . TRP A 1 665 ? 150.331 157.382 125.936 1.00 28.43  ? 658 TRP A CA  1 
ATOM   4931  C  C   . TRP A 1 665 ? 149.034 156.781 125.412 1.00 28.43  ? 658 TRP A C   1 
ATOM   4932  O  O   . TRP A 1 665 ? 149.018 155.633 124.950 1.00 28.43  ? 658 TRP A O   1 
ATOM   4933  C  CB  . TRP A 1 665 ? 150.408 157.273 127.460 1.00 28.43  ? 658 TRP A CB  1 
ATOM   4934  C  CG  . TRP A 1 665 ? 149.375 158.066 128.205 1.00 28.43  ? 658 TRP A CG  1 
ATOM   4935  C  CD1 . TRP A 1 665 ? 149.507 159.339 128.669 1.00 28.43  ? 658 TRP A CD1 1 
ATOM   4936  C  CD2 . TRP A 1 665 ? 148.069 157.630 128.602 1.00 28.43  ? 658 TRP A CD2 1 
ATOM   4937  N  NE1 . TRP A 1 665 ? 148.362 159.731 129.314 1.00 28.43  ? 658 TRP A NE1 1 
ATOM   4938  C  CE2 . TRP A 1 665 ? 147.463 158.698 129.287 1.00 28.43  ? 658 TRP A CE2 1 
ATOM   4939  C  CE3 . TRP A 1 665 ? 147.350 156.443 128.436 1.00 28.43  ? 658 TRP A CE3 1 
ATOM   4940  C  CZ2 . TRP A 1 665 ? 146.175 158.618 129.805 1.00 28.43  ? 658 TRP A CZ2 1 
ATOM   4941  C  CZ3 . TRP A 1 665 ? 146.070 156.366 128.954 1.00 28.43  ? 658 TRP A CZ3 1 
ATOM   4942  C  CH2 . TRP A 1 665 ? 145.497 157.446 129.628 1.00 28.43  ? 658 TRP A CH2 1 
ATOM   4943  N  N   . TRP A 1 666 ? 147.948 157.554 125.429 1.00 31.35  ? 659 TRP A N   1 
ATOM   4944  C  CA  . TRP A 1 666 ? 146.669 157.036 124.960 1.00 31.35  ? 659 TRP A CA  1 
ATOM   4945  C  C   . TRP A 1 666 ? 146.711 156.637 123.494 1.00 31.35  ? 659 TRP A C   1 
ATOM   4946  O  O   . TRP A 1 666 ? 145.838 155.889 123.044 1.00 31.35  ? 659 TRP A O   1 
ATOM   4947  C  CB  . TRP A 1 666 ? 145.561 158.066 125.180 1.00 31.35  ? 659 TRP A CB  1 
ATOM   4948  C  CG  . TRP A 1 666 ? 145.796 159.381 124.498 1.00 31.35  ? 659 TRP A CG  1 
ATOM   4949  C  CD1 . TRP A 1 666 ? 145.624 159.660 123.174 1.00 31.35  ? 659 TRP A CD1 1 
ATOM   4950  C  CD2 . TRP A 1 666 ? 146.220 160.604 125.112 1.00 31.35  ? 659 TRP A CD2 1 
ATOM   4951  N  NE1 . TRP A 1 666 ? 145.925 160.975 122.925 1.00 31.35  ? 659 TRP A NE1 1 
ATOM   4952  C  CE2 . TRP A 1 666 ? 146.293 161.576 124.099 1.00 31.35  ? 659 TRP A CE2 1 
ATOM   4953  C  CE3 . TRP A 1 666 ? 146.551 160.968 126.418 1.00 31.35  ? 659 TRP A CE3 1 
ATOM   4954  C  CZ2 . TRP A 1 666 ? 146.682 162.886 124.351 1.00 31.35  ? 659 TRP A CZ2 1 
ATOM   4955  C  CZ3 . TRP A 1 666 ? 146.937 162.268 126.664 1.00 31.35  ? 659 TRP A CZ3 1 
ATOM   4956  C  CH2 . TRP A 1 666 ? 147.000 163.211 125.638 1.00 31.35  ? 659 TRP A CH2 1 
ATOM   4957  N  N   . ASN A 1 667 ? 147.702 157.113 122.739 1.00 35.07  ? 660 ASN A N   1 
ATOM   4958  C  CA  . ASN A 1 667 ? 147.800 156.745 121.334 1.00 35.07  ? 660 ASN A CA  1 
ATOM   4959  C  C   . ASN A 1 667 ? 148.348 155.340 121.129 1.00 35.07  ? 660 ASN A C   1 
ATOM   4960  O  O   . ASN A 1 667 ? 148.214 154.798 120.027 1.00 35.07  ? 660 ASN A O   1 
ATOM   4961  C  CB  . ASN A 1 667 ? 148.671 157.754 120.584 1.00 35.07  ? 660 ASN A CB  1 
ATOM   4962  C  CG  . ASN A 1 667 ? 147.897 158.983 120.158 1.00 35.07  ? 660 ASN A CG  1 
ATOM   4963  O  OD1 . ASN A 1 667 ? 146.667 158.994 120.178 1.00 35.07  ? 660 ASN A OD1 1 
ATOM   4964  N  ND2 . ASN A 1 667 ? 148.614 160.026 119.763 1.00 35.07  ? 660 ASN A ND2 1 
ATOM   4965  N  N   . MET A 1 668 ? 148.953 154.739 122.149 1.00 35.69  ? 661 MET A N   1 
ATOM   4966  C  CA  . MET A 1 668 ? 149.449 153.375 122.044 1.00 35.69  ? 661 MET A CA  1 
ATOM   4967  C  C   . MET A 1 668 ? 148.334 152.380 122.333 1.00 35.69  ? 661 MET A C   1 
ATOM   4968  O  O   . MET A 1 668 ? 147.487 152.616 123.197 1.00 35.69  ? 661 MET A O   1 
ATOM   4969  C  CB  . MET A 1 668 ? 150.604 153.140 123.013 1.00 35.69  ? 661 MET A CB  1 
ATOM   4970  C  CG  . MET A 1 668 ? 151.055 151.697 123.064 1.00 35.69  ? 661 MET A CG  1 
ATOM   4971  S  SD  . MET A 1 668 ? 152.655 151.516 123.838 1.00 35.69  ? 661 MET A SD  1 
ATOM   4972  C  CE  . MET A 1 668 ? 152.212 152.039 125.482 1.00 35.69  ? 661 MET A CE  1 
ATOM   4973  N  N   . VAL A 1 669 ? 148.347 151.262 121.614 1.00 40.23  ? 662 VAL A N   1 
ATOM   4974  C  CA  . VAL A 1 669 ? 147.427 150.156 121.864 1.00 40.23  ? 662 VAL A CA  1 
ATOM   4975  C  C   . VAL A 1 669 ? 148.212 149.037 122.553 1.00 40.23  ? 662 VAL A C   1 
ATOM   4976  O  O   . VAL A 1 669 ? 149.153 148.494 121.952 1.00 40.23  ? 662 VAL A O   1 
ATOM   4977  C  CB  . VAL A 1 669 ? 146.746 149.678 120.574 1.00 40.23  ? 662 VAL A CB  1 
ATOM   4978  C  CG1 . VAL A 1 669 ? 147.760 149.256 119.517 1.00 40.23  ? 662 VAL A CG1 1 
ATOM   4979  C  CG2 . VAL A 1 669 ? 145.798 148.534 120.882 1.00 40.23  ? 662 VAL A CG2 1 
ATOM   4980  N  N   . PRO A 1 670 ? 147.903 148.702 123.814 1.00 42.34  ? 663 PRO A N   1 
ATOM   4981  C  CA  . PRO A 1 670 ? 148.561 147.616 124.546 1.00 42.34  ? 663 PRO A CA  1 
ATOM   4982  C  C   . PRO A 1 670 ? 148.143 146.238 124.047 1.00 42.34  ? 663 PRO A C   1 
ATOM   4983  O  O   . PRO A 1 670 ? 148.638 145.215 124.520 1.00 42.34  ? 663 PRO A O   1 
ATOM   4984  C  CB  . PRO A 1 670 ? 148.092 147.827 125.989 1.00 42.34  ? 663 PRO A CB  1 
ATOM   4985  C  CG  . PRO A 1 670 ? 147.610 149.235 126.040 1.00 42.34  ? 663 PRO A CG  1 
ATOM   4986  C  CD  . PRO A 1 670 ? 147.021 149.484 124.692 1.00 42.34  ? 663 PRO A CD  1 
ATOM   4987  O  OXT . PRO A 1 670 ? 147.290 146.115 123.169 1.00 42.34  ? 663 PRO A OXT 1 
ATOM   4988  N  N   . TYR B 2 1   ? 142.815 156.658 149.573 1.00 64.37  ? 1   TYR C N   1 
ATOM   4989  C  CA  . TYR B 2 1   ? 143.779 155.687 149.071 1.00 64.37  ? 1   TYR C CA  1 
ATOM   4990  C  C   . TYR B 2 1   ? 145.188 156.254 149.101 1.00 64.37  ? 1   TYR C C   1 
ATOM   4991  O  O   . TYR B 2 1   ? 145.909 156.092 150.084 1.00 64.37  ? 1   TYR C O   1 
ATOM   4992  C  CB  . TYR B 2 1   ? 143.423 155.257 147.648 1.00 64.37  ? 1   TYR C CB  1 
ATOM   4993  C  CG  . TYR B 2 1   ? 142.235 154.331 147.570 1.00 64.37  ? 1   TYR C CG  1 
ATOM   4994  C  CD1 . TYR B 2 1   ? 140.975 154.755 147.963 1.00 64.37  ? 1   TYR C CD1 1 
ATOM   4995  C  CD2 . TYR B 2 1   ? 142.374 153.032 147.103 1.00 64.37  ? 1   TYR C CD2 1 
ATOM   4996  C  CE1 . TYR B 2 1   ? 139.890 153.914 147.898 1.00 64.37  ? 1   TYR C CE1 1 
ATOM   4997  C  CE2 . TYR B 2 1   ? 141.291 152.183 147.032 1.00 64.37  ? 1   TYR C CE2 1 
ATOM   4998  C  CZ  . TYR B 2 1   ? 140.051 152.630 147.430 1.00 64.37  ? 1   TYR C CZ  1 
ATOM   4999  O  OH  . TYR B 2 1   ? 138.965 151.789 147.361 1.00 64.37  ? 1   TYR C OH  1 
ATOM   5000  N  N   . GLU B 2 2   ? 145.575 156.921 148.011 1.00 64.80  ? 2   GLU C N   1 
ATOM   5001  C  CA  . GLU B 2 2   ? 146.909 157.504 147.935 1.00 64.80  ? 2   GLU C CA  1 
ATOM   5002  C  C   . GLU B 2 2   ? 147.102 158.588 148.986 1.00 64.80  ? 2   GLU C C   1 
ATOM   5003  O  O   . GLU B 2 2   ? 148.232 158.835 149.423 1.00 64.80  ? 2   GLU C O   1 
ATOM   5004  C  CB  . GLU B 2 2   ? 147.153 158.065 146.534 1.00 64.80  ? 2   GLU C CB  1 
ATOM   5005  C  CG  . GLU B 2 2   ? 146.801 157.119 145.378 1.00 64.80  ? 2   GLU C CG  1 
ATOM   5006  C  CD  . GLU B 2 2   ? 147.651 155.851 145.299 1.00 64.80  ? 2   GLU C CD  1 
ATOM   5007  O  OE1 . GLU B 2 2   ? 147.838 155.347 144.172 1.00 64.80  ? 2   GLU C OE1 1 
ATOM   5008  O  OE2 . GLU B 2 2   ? 148.135 155.347 146.334 1.00 64.80  ? 2   GLU C OE2 1 
ATOM   5009  N  N   . SER B 2 3   ? 146.018 159.248 149.395 1.00 63.61  ? 3   SER C N   1 
ATOM   5010  C  CA  . SER B 2 3   ? 146.098 160.189 150.507 1.00 63.61  ? 3   SER C CA  1 
ATOM   5011  C  C   . SER B 2 3   ? 146.471 159.472 151.798 1.00 63.61  ? 3   SER C C   1 
ATOM   5012  O  O   . SER B 2 3   ? 147.279 159.970 152.589 1.00 63.61  ? 3   SER C O   1 
ATOM   5013  C  CB  . SER B 2 3   ? 144.770 160.929 150.663 1.00 63.61  ? 3   SER C CB  1 
ATOM   5014  O  OG  . SER B 2 3   ? 143.990 160.356 151.697 1.00 63.61  ? 3   SER C OG  1 
ATOM   5015  N  N   . CYS B 2 4   ? 145.887 158.293 152.027 1.00 63.38  ? 4   CYS C N   1 
ATOM   5016  C  CA  . CYS B 2 4   ? 146.211 157.524 153.225 1.00 63.38  ? 4   CYS C CA  1 
ATOM   5017  C  C   . CYS B 2 4   ? 147.676 157.107 153.233 1.00 63.38  ? 4   CYS C C   1 
ATOM   5018  O  O   . CYS B 2 4   ? 148.321 157.098 154.288 1.00 63.38  ? 4   CYS C O   1 
ATOM   5019  C  CB  . CYS B 2 4   ? 145.303 156.300 153.327 1.00 63.38  ? 4   CYS C CB  1 
ATOM   5020  S  SG  . CYS B 2 4   ? 143.568 156.685 153.652 1.00 63.38  ? 4   CYS C SG  1 
ATOM   5021  N  N   . ARG B 2 5   ? 148.217 156.749 152.066 1.00 62.34  ? 5   ARG C N   1 
ATOM   5022  C  CA  . ARG B 2 5   ? 149.643 156.454 151.970 1.00 62.34  ? 5   ARG C CA  1 
ATOM   5023  C  C   . ARG B 2 5   ? 150.468 157.678 152.340 1.00 62.34  ? 5   ARG C C   1 
ATOM   5024  O  O   . ARG B 2 5   ? 151.504 157.571 153.007 1.00 62.34  ? 5   ARG C O   1 
ATOM   5025  C  CB  . ARG B 2 5   ? 149.990 155.984 150.557 1.00 62.34  ? 5   ARG C CB  1 
ATOM   5026  C  CG  . ARG B 2 5   ? 149.079 154.904 150.009 1.00 62.34  ? 5   ARG C CG  1 
ATOM   5027  C  CD  . ARG B 2 5   ? 149.513 153.519 150.442 1.00 62.34  ? 5   ARG C CD  1 
ATOM   5028  N  NE  . ARG B 2 5   ? 149.091 152.507 149.482 1.00 62.34  ? 5   ARG C NE  1 
ATOM   5029  C  CZ  . ARG B 2 5   ? 148.262 151.510 149.758 1.00 62.34  ? 5   ARG C CZ  1 
ATOM   5030  N  NH1 . ARG B 2 5   ? 147.745 151.356 150.965 1.00 62.34  ? 5   ARG C NH1 1 
ATOM   5031  N  NH2 . ARG B 2 5   ? 147.943 150.648 148.798 1.00 62.34  ? 5   ARG C NH2 1 
ATOM   5032  N  N   . TYR B 2 6   ? 150.020 158.858 151.903 1.00 63.01  ? 6   TYR C N   1 
ATOM   5033  C  CA  . TYR B 2 6   ? 150.716 160.096 152.236 1.00 63.01  ? 6   TYR C CA  1 
ATOM   5034  C  C   . TYR B 2 6   ? 150.756 160.324 153.741 1.00 63.01  ? 6   TYR C C   1 
ATOM   5035  O  O   . TYR B 2 6   ? 151.805 160.659 154.302 1.00 63.01  ? 6   TYR C O   1 
ATOM   5036  C  CB  . TYR B 2 6   ? 150.035 161.274 151.544 1.00 63.01  ? 6   TYR C CB  1 
ATOM   5037  C  CG  . TYR B 2 6   ? 150.635 162.606 151.913 1.00 63.01  ? 6   TYR C CG  1 
ATOM   5038  C  CD1 . TYR B 2 6   ? 151.835 163.029 151.368 1.00 63.01  ? 6   TYR C CD1 1 
ATOM   5039  C  CD2 . TYR B 2 6   ? 150.015 163.424 152.843 1.00 63.01  ? 6   TYR C CD2 1 
ATOM   5040  C  CE1 . TYR B 2 6   ? 152.384 164.244 151.717 1.00 63.01  ? 6   TYR C CE1 1 
ATOM   5041  C  CE2 . TYR B 2 6   ? 150.562 164.633 153.201 1.00 63.01  ? 6   TYR C CE2 1 
ATOM   5042  C  CZ  . TYR B 2 6   ? 151.746 165.041 152.634 1.00 63.01  ? 6   TYR C CZ  1 
ATOM   5043  O  OH  . TYR B 2 6   ? 152.294 166.252 152.989 1.00 63.01  ? 6   TYR C OH  1 
ATOM   5044  N  N   . ARG B 2 7   ? 149.615 160.159 154.412 1.00 62.46  ? 7   ARG C N   1 
ATOM   5045  C  CA  . ARG B 2 7   ? 149.560 160.410 155.848 1.00 62.46  ? 7   ARG C CA  1 
ATOM   5046  C  C   . ARG B 2 7   ? 150.419 159.413 156.614 1.00 62.46  ? 7   ARG C C   1 
ATOM   5047  O  O   . ARG B 2 7   ? 151.110 159.777 157.572 1.00 62.46  ? 7   ARG C O   1 
ATOM   5048  C  CB  . ARG B 2 7   ? 148.110 160.368 156.331 1.00 62.46  ? 7   ARG C CB  1 
ATOM   5049  C  CG  . ARG B 2 7   ? 147.959 160.417 157.840 1.00 62.46  ? 7   ARG C CG  1 
ATOM   5050  C  CD  . ARG B 2 7   ? 148.257 161.808 158.376 1.00 62.46  ? 7   ARG C CD  1 
ATOM   5051  N  NE  . ARG B 2 7   ? 147.812 162.858 157.468 1.00 62.46  ? 7   ARG C NE  1 
ATOM   5052  C  CZ  . ARG B 2 7   ? 146.566 163.302 157.387 1.00 62.46  ? 7   ARG C CZ  1 
ATOM   5053  N  NH1 . ARG B 2 7   ? 145.604 162.804 158.147 1.00 62.46  ? 7   ARG C NH1 1 
ATOM   5054  N  NH2 . ARG B 2 7   ? 146.277 164.271 156.524 1.00 62.46  ? 7   ARG C NH2 1 
ATOM   5055  N  N   . GLN B 2 8   ? 150.389 158.144 156.200 1.00 62.77  ? 8   GLN C N   1 
ATOM   5056  C  CA  . GLN B 2 8   ? 151.165 157.118 156.890 1.00 62.77  ? 8   GLN C CA  1 
ATOM   5057  C  C   . GLN B 2 8   ? 152.660 157.392 156.785 1.00 62.77  ? 8   GLN C C   1 
ATOM   5058  O  O   . GLN B 2 8   ? 153.406 157.212 157.755 1.00 62.77  ? 8   GLN C O   1 
ATOM   5059  C  CB  . GLN B 2 8   ? 150.825 155.740 156.323 1.00 62.77  ? 8   GLN C CB  1 
ATOM   5060  C  CG  . GLN B 2 8   ? 150.986 154.604 157.316 1.00 62.77  ? 8   GLN C CG  1 
ATOM   5061  C  CD  . GLN B 2 8   ? 151.032 153.248 156.642 1.00 62.77  ? 8   GLN C CD  1 
ATOM   5062  O  OE1 . GLN B 2 8   ? 150.207 152.941 155.782 1.00 62.77  ? 8   GLN C OE1 1 
ATOM   5063  N  NE2 . GLN B 2 8   ? 152.001 152.427 157.030 1.00 62.77  ? 8   GLN C NE2 1 
ATOM   5064  N  N   . VAL B 2 9   ? 153.119 157.822 155.608 1.00 59.71  ? 9   VAL C N   1 
ATOM   5065  C  CA  . VAL B 2 9   ? 154.539 158.112 155.427 1.00 59.71  ? 9   VAL C CA  1 
ATOM   5066  C  C   . VAL B 2 9   ? 154.952 159.312 156.270 1.00 59.71  ? 9   VAL C C   1 
ATOM   5067  O  O   . VAL B 2 9   ? 156.001 159.296 156.926 1.00 59.71  ? 9   VAL C O   1 
ATOM   5068  C  CB  . VAL B 2 9   ? 154.853 158.331 153.937 1.00 59.71  ? 9   VAL C CB  1 
ATOM   5069  C  CG1 . VAL B 2 9   ? 156.209 158.992 153.774 1.00 59.71  ? 9   VAL C CG1 1 
ATOM   5070  C  CG2 . VAL B 2 9   ? 154.809 157.010 153.194 1.00 59.71  ? 9   VAL C CG2 1 
ATOM   5071  N  N   . LEU B 2 10  ? 154.135 160.367 156.269 1.00 60.62  ? 10  LEU C N   1 
ATOM   5072  C  CA  . LEU B 2 10  ? 154.476 161.574 157.017 1.00 60.62  ? 10  LEU C CA  1 
ATOM   5073  C  C   . LEU B 2 10  ? 154.561 161.289 158.511 1.00 60.62  ? 10  LEU C C   1 
ATOM   5074  O  O   . LEU B 2 10  ? 155.384 161.877 159.222 1.00 60.62  ? 10  LEU C O   1 
ATOM   5075  C  CB  . LEU B 2 10  ? 153.453 162.673 156.733 1.00 60.62  ? 10  LEU C CB  1 
ATOM   5076  C  CG  . LEU B 2 10  ? 153.751 164.044 157.341 1.00 60.62  ? 10  LEU C CG  1 
ATOM   5077  C  CD1 . LEU B 2 10  ? 155.087 164.568 156.846 1.00 60.62  ? 10  LEU C CD1 1 
ATOM   5078  C  CD2 . LEU B 2 10  ? 152.638 165.025 157.016 1.00 60.62  ? 10  LEU C CD2 1 
ATOM   5079  N  N   . GLN B 2 11  ? 153.708 160.389 159.005 1.00 61.23  ? 11  GLN C N   1 
ATOM   5080  C  CA  . GLN B 2 11  ? 153.768 160.007 160.411 1.00 61.23  ? 11  GLN C CA  1 
ATOM   5081  C  C   . GLN B 2 11  ? 155.106 159.362 160.749 1.00 61.23  ? 11  GLN C C   1 
ATOM   5082  O  O   . GLN B 2 11  ? 155.686 159.629 161.807 1.00 61.23  ? 11  GLN C O   1 
ATOM   5083  C  CB  . GLN B 2 11  ? 152.616 159.058 160.744 1.00 61.23  ? 11  GLN C CB  1 
ATOM   5084  C  CG  . GLN B 2 11  ? 152.544 158.653 162.206 1.00 61.23  ? 11  GLN C CG  1 
ATOM   5085  C  CD  . GLN B 2 11  ? 151.619 157.474 162.438 1.00 61.23  ? 11  GLN C CD  1 
ATOM   5086  O  OE1 . GLN B 2 11  ? 151.016 156.950 161.502 1.00 61.23  ? 11  GLN C OE1 1 
ATOM   5087  N  NE2 . GLN B 2 11  ? 151.502 157.052 163.691 1.00 61.23  ? 11  GLN C NE2 1 
ATOM   5088  N  N   . LEU B 2 12  ? 155.613 158.515 159.860 1.00 59.95  ? 12  LEU C N   1 
ATOM   5089  C  CA  . LEU B 2 12  ? 156.896 157.859 160.073 1.00 59.95  ? 12  LEU C CA  1 
ATOM   5090  C  C   . LEU B 2 12  ? 158.049 158.792 159.722 1.00 59.95  ? 12  LEU C C   1 
ATOM   5091  O  O   . LEU B 2 12  ? 157.891 159.730 158.941 1.00 59.95  ? 12  LEU C O   1 
ATOM   5092  C  CB  . LEU B 2 12  ? 156.987 156.576 159.247 1.00 59.95  ? 12  LEU C CB  1 
ATOM   5093  C  CG  . LEU B 2 12  ? 158.182 155.668 159.537 1.00 59.95  ? 12  LEU C CG  1 
ATOM   5094  C  CD1 . LEU B 2 12  ? 158.349 155.463 161.034 1.00 59.95  ? 12  LEU C CD1 1 
ATOM   5095  C  CD2 . LEU B 2 12  ? 158.018 154.335 158.832 1.00 59.95  ? 12  LEU C CD2 1 
HETATM 5096  N  N   . NH2 B 2 13  ? 159.241 158.536 160.266 1.00 30.00  ? 13  NH2 C N   1 
ATOM   5097  N  N   . TYR C 2 1   ? 142.135 128.232 149.520 1.00 64.37  ? 1   TYR D N   1 
ATOM   5098  C  CA  . TYR C 2 1   ? 141.163 129.188 149.006 1.00 64.37  ? 1   TYR D CA  1 
ATOM   5099  C  C   . TYR C 2 1   ? 139.758 128.612 149.049 1.00 64.37  ? 1   TYR D C   1 
ATOM   5100  O  O   . TYR C 2 1   ? 139.039 128.784 150.032 1.00 64.37  ? 1   TYR D O   1 
ATOM   5101  C  CB  . TYR C 2 1   ? 141.511 129.599 147.575 1.00 64.37  ? 1   TYR D CB  1 
ATOM   5102  C  CG  . TYR C 2 1   ? 142.693 130.531 147.479 1.00 64.37  ? 1   TYR D CG  1 
ATOM   5103  C  CD1 . TYR C 2 1   ? 143.957 130.122 147.874 1.00 64.37  ? 1   TYR D CD1 1 
ATOM   5104  C  CD2 . TYR C 2 1   ? 142.543 131.822 146.992 1.00 64.37  ? 1   TYR D CD2 1 
ATOM   5105  C  CE1 . TYR C 2 1   ? 145.036 130.970 147.793 1.00 64.37  ? 1   TYR D CE1 1 
ATOM   5106  C  CE2 . TYR C 2 1   ? 143.620 132.677 146.905 1.00 64.37  ? 1   TYR D CE2 1 
ATOM   5107  C  CZ  . TYR C 2 1   ? 144.864 132.245 147.305 1.00 64.37  ? 1   TYR D CZ  1 
ATOM   5108  O  OH  . TYR C 2 1   ? 145.944 133.092 147.220 1.00 64.37  ? 1   TYR D OH  1 
ATOM   5109  N  N   . GLU C 2 2   ? 139.372 127.926 147.971 1.00 64.80  ? 2   GLU D N   1 
ATOM   5110  C  CA  . GLU C 2 2   ? 138.042 127.332 147.909 1.00 64.80  ? 2   GLU D CA  1 
ATOM   5111  C  C   . GLU C 2 2   ? 137.860 126.263 148.977 1.00 64.80  ? 2   GLU D C   1 
ATOM   5112  O  O   . GLU C 2 2   ? 136.733 126.016 149.421 1.00 64.80  ? 2   GLU D O   1 
ATOM   5113  C  CB  . GLU C 2 2   ? 137.797 126.748 146.517 1.00 64.80  ? 2   GLU D CB  1 
ATOM   5114  C  CG  . GLU C 2 2   ? 138.139 127.678 145.346 1.00 64.80  ? 2   GLU D CG  1 
ATOM   5115  C  CD  . GLU C 2 2   ? 137.280 128.939 145.250 1.00 64.80  ? 2   GLU D CD  1 
ATOM   5116  O  OE1 . GLU C 2 2   ? 137.086 129.424 144.116 1.00 64.80  ? 2   GLU D OE1 1 
ATOM   5117  O  OE2 . GLU C 2 2   ? 136.796 129.456 146.279 1.00 64.80  ? 2   GLU D OE2 1 
ATOM   5118  N  N   . SER C 2 3   ? 138.950 125.617 149.392 1.00 63.61  ? 3   SER D N   1 
ATOM   5119  C  CA  . SER C 2 3   ? 138.880 124.693 150.519 1.00 63.61  ? 3   SER D CA  1 
ATOM   5120  C  C   . SER C 2 3   ? 138.506 125.428 151.800 1.00 63.61  ? 3   SER D C   1 
ATOM   5121  O  O   . SER C 2 3   ? 137.704 124.936 152.601 1.00 63.61  ? 3   SER D O   1 
ATOM   5122  C  CB  . SER C 2 3   ? 140.214 123.965 150.682 1.00 63.61  ? 3   SER D CB  1 
ATOM   5123  O  OG  . SER C 2 3   ? 140.993 124.559 151.705 1.00 63.61  ? 3   SER D OG  1 
ATOM   5124  N  N   . CYS C 2 4   ? 139.083 126.614 152.009 1.00 63.38  ? 4   CYS D N   1 
ATOM   5125  C  CA  . CYS C 2 4   ? 138.757 127.399 153.196 1.00 63.38  ? 4   CYS D CA  1 
ATOM   5126  C  C   . CYS C 2 4   ? 137.289 127.806 153.202 1.00 63.38  ? 4   CYS D C   1 
ATOM   5127  O  O   . CYS C 2 4   ? 136.648 127.827 154.259 1.00 63.38  ? 4   CYS D O   1 
ATOM   5128  C  CB  . CYS C 2 4   ? 139.657 128.631 153.276 1.00 63.38  ? 4   CYS D CB  1 
ATOM   5129  S  SG  . CYS C 2 4   ? 141.396 128.263 153.601 1.00 63.38  ? 4   CYS D SG  1 
ATOM   5130  N  N   . ARG C 2 5   ? 136.742 128.142 152.032 1.00 62.34  ? 5   ARG D N   1 
ATOM   5131  C  CA  . ARG C 2 5   ? 135.314 128.426 151.936 1.00 62.34  ? 5   ARG D CA  1 
ATOM   5132  C  C   . ARG C 2 5   ? 134.499 127.202 152.328 1.00 62.34  ? 5   ARG D C   1 
ATOM   5133  O  O   . ARG C 2 5   ? 133.464 127.312 152.996 1.00 62.34  ? 5   ARG D O   1 
ATOM   5134  C  CB  . ARG C 2 5   ? 134.959 128.872 150.517 1.00 62.34  ? 5   ARG D CB  1 
ATOM   5135  C  CG  . ARG C 2 5   ? 135.861 129.949 149.949 1.00 62.34  ? 5   ARG D CG  1 
ATOM   5136  C  CD  . ARG C 2 5   ? 135.419 131.338 150.362 1.00 62.34  ? 5   ARG D CD  1 
ATOM   5137  N  NE  . ARG C 2 5   ? 135.830 132.338 149.385 1.00 62.34  ? 5   ARG D NE  1 
ATOM   5138  C  CZ  . ARG C 2 5   ? 136.653 133.344 149.643 1.00 62.34  ? 5   ARG D CZ  1 
ATOM   5139  N  NH1 . ARG C 2 5   ? 137.173 133.521 150.846 1.00 62.34  ? 5   ARG D NH1 1 
ATOM   5140  N  NH2 . ARG C 2 5   ? 136.963 134.194 148.669 1.00 62.34  ? 5   ARG D NH2 1 
ATOM   5141  N  N   . TYR C 2 6   ? 134.953 126.019 151.907 1.00 63.01  ? 6   TYR D N   1 
ATOM   5142  C  CA  . TYR C 2 6   ? 134.267 124.781 152.262 1.00 63.01  ? 6   TYR D CA  1 
ATOM   5143  C  C   . TYR C 2 6   ? 134.233 124.576 153.770 1.00 63.01  ? 6   TYR D C   1 
ATOM   5144  O  O   . TYR C 2 6   ? 133.189 124.243 154.340 1.00 63.01  ? 6   TYR D O   1 
ATOM   5145  C  CB  . TYR C 2 6   ? 134.954 123.597 151.586 1.00 63.01  ? 6   TYR D CB  1 
ATOM   5146  C  CG  . TYR C 2 6   ? 134.364 122.267 151.978 1.00 63.01  ? 6   TYR D CG  1 
ATOM   5147  C  CD1 . TYR C 2 6   ? 133.166 121.827 151.443 1.00 63.01  ? 6   TYR D CD1 1 
ATOM   5148  C  CD2 . TYR C 2 6   ? 134.993 121.468 152.918 1.00 63.01  ? 6   TYR D CD2 1 
ATOM   5149  C  CE1 . TYR C 2 6   ? 132.626 120.614 151.813 1.00 63.01  ? 6   TYR D CE1 1 
ATOM   5150  C  CE2 . TYR C 2 6   ? 134.456 120.261 153.296 1.00 63.01  ? 6   TYR D CE2 1 
ATOM   5151  C  CZ  . TYR C 2 6   ? 133.273 119.836 152.740 1.00 63.01  ? 6   TYR D CZ  1 
ATOM   5152  O  OH  . TYR C 2 6   ? 132.734 118.627 153.115 1.00 63.01  ? 6   TYR D OH  1 
ATOM   5153  N  N   . ARG C 2 7   ? 135.375 124.759 154.435 1.00 62.46  ? 7   ARG D N   1 
ATOM   5154  C  CA  . ARG C 2 7   ? 135.437 124.531 155.874 1.00 62.46  ? 7   ARG D CA  1 
ATOM   5155  C  C   . ARG C 2 7   ? 134.573 125.534 156.628 1.00 62.46  ? 7   ARG D C   1 
ATOM   5156  O  O   . ARG C 2 7   ? 133.888 125.180 157.594 1.00 62.46  ? 7   ARG D O   1 
ATOM   5157  C  CB  . ARG C 2 7   ? 136.888 124.591 156.352 1.00 62.46  ? 7   ARG D CB  1 
ATOM   5158  C  CG  . ARG C 2 7   ? 137.044 124.566 157.861 1.00 62.46  ? 7   ARG D CG  1 
ATOM   5159  C  CD  . ARG C 2 7   ? 136.758 123.181 158.419 1.00 62.46  ? 7   ARG D CD  1 
ATOM   5160  N  NE  . ARG C 2 7   ? 137.207 122.121 157.526 1.00 62.46  ? 7   ARG D NE  1 
ATOM   5161  C  CZ  . ARG C 2 7   ? 138.456 121.684 157.448 1.00 62.46  ? 7   ARG D CZ  1 
ATOM   5162  N  NH1 . ARG C 2 7   ? 139.417 122.200 158.197 1.00 62.46  ? 7   ARG D NH1 1 
ATOM   5163  N  NH2 . ARG C 2 7   ? 138.749 120.704 156.599 1.00 62.46  ? 7   ARG D NH2 1 
ATOM   5164  N  N   . GLN C 2 8   ? 134.593 126.797 156.194 1.00 62.77  ? 8   GLN D N   1 
ATOM   5165  C  CA  . GLN C 2 8   ? 133.812 127.828 156.871 1.00 62.77  ? 8   GLN D CA  1 
ATOM   5166  C  C   . GLN C 2 8   ? 132.319 127.542 156.775 1.00 62.77  ? 8   GLN D C   1 
ATOM   5167  O  O   . GLN C 2 8   ? 131.575 127.732 157.745 1.00 62.77  ? 8   GLN D O   1 
ATOM   5168  C  CB  . GLN C 2 8   ? 134.141 129.199 156.281 1.00 62.77  ? 8   GLN D CB  1 
ATOM   5169  C  CG  . GLN C 2 8   ? 133.975 130.349 157.257 1.00 62.77  ? 8   GLN D CG  1 
ATOM   5170  C  CD  . GLN C 2 8   ? 133.918 131.694 156.562 1.00 62.77  ? 8   GLN D CD  1 
ATOM   5171  O  OE1 . GLN C 2 8   ? 134.738 131.994 155.695 1.00 62.77  ? 8   GLN D OE1 1 
ATOM   5172  N  NE2 . GLN C 2 8   ? 132.944 132.514 156.941 1.00 62.77  ? 8   GLN D NE2 1 
ATOM   5173  N  N   . VAL C 2 9   ? 131.859 127.091 155.606 1.00 59.71  ? 9   VAL D N   1 
ATOM   5174  C  CA  . VAL C 2 9   ? 130.441 126.788 155.435 1.00 59.71  ? 9   VAL D CA  1 
ATOM   5175  C  C   . VAL C 2 9   ? 130.039 125.598 156.297 1.00 59.71  ? 9   VAL D C   1 
ATOM   5176  O  O   . VAL C 2 9   ? 128.992 125.617 156.957 1.00 59.71  ? 9   VAL D O   1 
ATOM   5177  C  CB  . VAL C 2 9   ? 130.123 126.544 153.949 1.00 59.71  ? 9   VAL D CB  1 
ATOM   5178  C  CG1 . VAL C 2 9   ? 128.772 125.871 153.801 1.00 59.71  ? 9   VAL D CG1 1 
ATOM   5179  C  CG2 . VAL C 2 9   ? 130.156 127.853 153.186 1.00 59.71  ? 9   VAL D CG2 1 
ATOM   5180  N  N   . LEU C 2 10  ? 130.863 124.549 156.310 1.00 60.62  ? 10  LEU D N   1 
ATOM   5181  C  CA  . LEU C 2 10  ? 130.533 123.352 157.078 1.00 60.62  ? 10  LEU D CA  1 
ATOM   5182  C  C   . LEU C 2 10  ? 130.451 123.659 158.567 1.00 60.62  ? 10  LEU D C   1 
ATOM   5183  O  O   . LEU C 2 10  ? 129.634 123.077 159.290 1.00 60.62  ? 10  LEU D O   1 
ATOM   5184  C  CB  . LEU C 2 10  ? 131.563 122.255 156.807 1.00 60.62  ? 10  LEU D CB  1 
ATOM   5185  C  CG  . LEU C 2 10  ? 131.276 120.892 157.437 1.00 60.62  ? 10  LEU D CG  1 
ATOM   5186  C  CD1 . LEU C 2 10  ? 129.942 120.351 156.955 1.00 60.62  ? 10  LEU D CD1 1 
ATOM   5187  C  CD2 . LEU C 2 10  ? 132.395 119.914 157.124 1.00 60.62  ? 10  LEU D CD2 1 
ATOM   5188  N  N   . GLN C 2 11  ? 131.299 124.572 159.045 1.00 61.23  ? 11  GLN D N   1 
ATOM   5189  C  CA  . GLN C 2 11  ? 131.241 124.976 160.445 1.00 61.23  ? 11  GLN D CA  1 
ATOM   5190  C  C   . GLN C 2 11  ? 129.900 125.617 160.777 1.00 61.23  ? 11  GLN D C   1 
ATOM   5191  O  O   . GLN C 2 11  ? 129.325 125.362 161.841 1.00 61.23  ? 11  GLN D O   1 
ATOM   5192  C  CB  . GLN C 2 11  ? 132.387 125.938 160.759 1.00 61.23  ? 11  GLN D CB  1 
ATOM   5193  C  CG  . GLN C 2 11  ? 132.461 126.366 162.214 1.00 61.23  ? 11  GLN D CG  1 
ATOM   5194  C  CD  . GLN C 2 11  ? 133.379 127.555 162.425 1.00 61.23  ? 11  GLN D CD  1 
ATOM   5195  O  OE1 . GLN C 2 11  ? 133.975 128.068 161.479 1.00 61.23  ? 11  GLN D OE1 1 
ATOM   5196  N  NE2 . GLN C 2 11  ? 133.497 127.997 163.671 1.00 61.23  ? 11  GLN D NE2 1 
ATOM   5197  N  N   . LEU C 2 12  ? 129.384 126.446 159.877 1.00 59.95  ? 12  LEU D N   1 
ATOM   5198  C  CA  . LEU C 2 12  ? 128.097 127.097 160.084 1.00 59.95  ? 12  LEU D CA  1 
ATOM   5199  C  C   . LEU C 2 12  ? 126.949 126.150 159.751 1.00 59.95  ? 12  LEU D C   1 
ATOM   5200  O  O   . LEU C 2 12  ? 127.163 125.038 159.267 1.00 59.95  ? 12  LEU D O   1 
ATOM   5201  C  CB  . LEU C 2 12  ? 127.994 128.366 159.239 1.00 59.95  ? 12  LEU D CB  1 
ATOM   5202  C  CG  . LEU C 2 12  ? 126.794 129.270 159.518 1.00 59.95  ? 12  LEU D CG  1 
ATOM   5203  C  CD1 . LEU C 2 12  ? 126.631 129.497 161.013 1.00 59.95  ? 12  LEU D CD1 1 
ATOM   5204  C  CD2 . LEU C 2 12  ? 126.947 130.593 158.792 1.00 59.95  ? 12  LEU D CD2 1 
HETATM 5205  N  N   . NH2 C 2 13  ? 125.707 126.576 159.988 1.00 30.00  ? 13  NH2 D N   1 
ATOM   5206  N  N   . GLY D 1 11  ? 167.712 131.598 123.094 1.00 103.09 ? 4   GLY B N   1 
ATOM   5207  C  CA  . GLY D 1 11  ? 168.929 131.289 122.366 1.00 103.09 ? 4   GLY B CA  1 
ATOM   5208  C  C   . GLY D 1 11  ? 170.103 130.927 123.253 1.00 103.09 ? 4   GLY B C   1 
ATOM   5209  O  O   . GLY D 1 11  ? 169.973 130.858 124.473 1.00 103.09 ? 4   GLY B O   1 
ATOM   5210  N  N   . THR D 1 12  ? 171.256 130.689 122.630 1.00 104.05 ? 5   THR B N   1 
ATOM   5211  C  CA  . THR D 1 12  ? 172.479 130.357 123.348 1.00 104.05 ? 5   THR B CA  1 
ATOM   5212  C  C   . THR D 1 12  ? 173.645 131.012 122.627 1.00 104.05 ? 5   THR B C   1 
ATOM   5213  O  O   . THR D 1 12  ? 173.808 130.826 121.418 1.00 104.05 ? 5   THR B O   1 
ATOM   5214  C  CB  . THR D 1 12  ? 172.692 128.843 123.432 1.00 104.05 ? 5   THR B CB  1 
ATOM   5215  O  OG1 . THR D 1 12  ? 171.429 128.189 123.600 1.00 104.05 ? 5   THR B OG1 1 
ATOM   5216  C  CG2 . THR D 1 12  ? 173.605 128.501 124.599 1.00 104.05 ? 5   THR B CG2 1 
ATOM   5217  N  N   . LEU D 1 13  ? 174.433 131.791 123.357 1.00 104.55 ? 6   LEU B N   1 
ATOM   5218  C  CA  . LEU D 1 13  ? 175.571 132.499 122.786 1.00 104.55 ? 6   LEU B CA  1 
ATOM   5219  C  C   . LEU D 1 13  ? 176.851 131.926 123.370 1.00 104.55 ? 6   LEU B C   1 
ATOM   5220  O  O   . LEU D 1 13  ? 177.121 132.096 124.564 1.00 104.55 ? 6   LEU B O   1 
ATOM   5221  C  CB  . LEU D 1 13  ? 175.490 133.998 123.062 1.00 104.55 ? 6   LEU B CB  1 
ATOM   5222  C  CG  . LEU D 1 13  ? 176.492 134.871 122.303 1.00 104.55 ? 6   LEU B CG  1 
ATOM   5223  C  CD1 . LEU D 1 13  ? 175.805 135.573 121.143 1.00 104.55 ? 6   LEU B CD1 1 
ATOM   5224  C  CD2 . LEU D 1 13  ? 177.141 135.880 123.232 1.00 104.55 ? 6   LEU B CD2 1 
ATOM   5225  N  N   . ILE D 1 14  ? 177.643 131.270 122.529 1.00 99.91  ? 7   ILE B N   1 
ATOM   5226  C  CA  . ILE D 1 14  ? 178.933 130.729 122.928 1.00 99.91  ? 7   ILE B CA  1 
ATOM   5227  C  C   . ILE D 1 14  ? 179.995 131.311 122.010 1.00 99.91  ? 7   ILE B C   1 
ATOM   5228  O  O   . ILE D 1 14  ? 179.915 131.173 120.784 1.00 99.91  ? 7   ILE B O   1 
ATOM   5229  C  CB  . ILE D 1 14  ? 178.949 129.191 122.883 1.00 99.91  ? 7   ILE B CB  1 
ATOM   5230  C  CG1 . ILE D 1 14  ? 178.204 128.677 121.649 1.00 99.91  ? 7   ILE B CG1 1 
ATOM   5231  C  CG2 . ILE D 1 14  ? 178.360 128.618 124.167 1.00 99.91  ? 7   ILE B CG2 1 
ATOM   5232  C  CD1 . ILE D 1 14  ? 178.081 127.178 121.613 1.00 99.91  ? 7   ILE B CD1 1 
ATOM   5233  N  N   . ARG D 1 15  ? 180.932 132.031 122.632 1.00 105.58 ? 8   ARG B N   1 
ATOM   5234  C  CA  . ARG D 1 15  ? 182.054 132.621 121.867 1.00 105.58 ? 8   ARG B CA  1 
ATOM   5235  C  C   . ARG D 1 15  ? 183.259 131.697 122.046 1.00 105.58 ? 8   ARG B C   1 
ATOM   5236  O  O   . ARG D 1 15  ? 183.348 131.036 123.099 1.00 105.58 ? 8   ARG B O   1 
ATOM   5237  C  CB  . ARG D 1 15  ? 182.336 134.047 122.350 1.00 105.58 ? 8   ARG B CB  1 
ATOM   5238  C  CG  . ARG D 1 15  ? 182.687 134.143 123.827 1.00 105.58 ? 8   ARG B CG  1 
ATOM   5239  C  CD  . ARG D 1 15  ? 182.577 135.563 124.344 1.00 105.58 ? 8   ARG B CD  1 
ATOM   5240  N  NE  . ARG D 1 15  ? 181.199 136.016 124.451 1.00 105.58 ? 8   ARG B NE  1 
ATOM   5241  C  CZ  . ARG D 1 15  ? 180.620 136.387 125.587 1.00 105.58 ? 8   ARG B CZ  1 
ATOM   5242  N  NH1 . ARG D 1 15  ? 181.213 136.140 126.742 1.00 105.58 ? 8   ARG B NH1 1 
ATOM   5243  N  NH2 . ARG D 1 15  ? 179.449 136.999 125.565 1.00 105.58 ? 8   ARG B NH2 1 
ATOM   5244  N  N   . VAL D 1 16  ? 184.136 131.649 121.051 1.00 110.41 ? 9   VAL B N   1 
ATOM   5245  C  CA  . VAL D 1 16  ? 185.294 130.758 121.082 1.00 110.41 ? 9   VAL B CA  1 
ATOM   5246  C  C   . VAL D 1 16  ? 186.552 131.574 121.343 1.00 110.41 ? 9   VAL B C   1 
ATOM   5247  O  O   . VAL D 1 16  ? 186.655 132.732 120.917 1.00 110.41 ? 9   VAL B O   1 
ATOM   5248  C  CB  . VAL D 1 16  ? 185.413 129.948 119.777 1.00 110.41 ? 9   VAL B CB  1 
ATOM   5249  C  CG1 . VAL D 1 16  ? 184.045 129.424 119.352 1.00 110.41 ? 9   VAL B CG1 1 
ATOM   5250  C  CG2 . VAL D 1 16  ? 186.036 130.787 118.665 1.00 110.41 ? 9   VAL B CG2 1 
ATOM   5251  N  N   . THR D 1 17  ? 187.487 130.992 122.091 1.00 116.54 ? 10  THR B N   1 
ATOM   5252  C  CA  . THR D 1 17  ? 188.781 131.593 122.357 1.00 116.54 ? 10  THR B CA  1 
ATOM   5253  C  C   . THR D 1 17  ? 189.875 130.643 121.896 1.00 116.54 ? 10  THR B C   1 
ATOM   5254  O  O   . THR D 1 17  ? 189.883 129.474 122.308 1.00 116.54 ? 10  THR B O   1 
ATOM   5255  C  CB  . THR D 1 17  ? 188.959 131.901 123.852 1.00 116.54 ? 10  THR B CB  1 
ATOM   5256  O  OG1 . THR D 1 17  ? 189.448 130.732 124.522 1.00 116.54 ? 10  THR B OG1 1 
ATOM   5257  C  CG2 . THR D 1 17  ? 187.635 132.337 124.472 1.00 116.54 ? 10  THR B CG2 1 
ATOM   5258  N  N   . PRO D 1 18  ? 190.799 131.085 121.040 1.00 120.39 ? 11  PRO B N   1 
ATOM   5259  C  CA  . PRO D 1 18  ? 191.880 130.187 120.601 1.00 120.39 ? 11  PRO B CA  1 
ATOM   5260  C  C   . PRO D 1 18  ? 192.814 129.756 121.717 1.00 120.39 ? 11  PRO B C   1 
ATOM   5261  O  O   . PRO D 1 18  ? 193.555 128.783 121.530 1.00 120.39 ? 11  PRO B O   1 
ATOM   5262  C  CB  . PRO D 1 18  ? 192.627 131.020 119.547 1.00 120.39 ? 11  PRO B CB  1 
ATOM   5263  C  CG  . PRO D 1 18  ? 191.665 132.098 119.145 1.00 120.39 ? 11  PRO B CG  1 
ATOM   5264  C  CD  . PRO D 1 18  ? 190.851 132.390 120.363 1.00 120.39 ? 11  PRO B CD  1 
ATOM   5265  N  N   . GLU D 1 19  ? 192.818 130.450 122.858 1.00 121.99 ? 12  GLU B N   1 
ATOM   5266  C  CA  . GLU D 1 19  ? 193.761 130.121 123.924 1.00 121.99 ? 12  GLU B CA  1 
ATOM   5267  C  C   . GLU D 1 19  ? 193.535 128.712 124.460 1.00 121.99 ? 12  GLU B C   1 
ATOM   5268  O  O   . GLU D 1 19  ? 194.493 127.955 124.658 1.00 121.99 ? 12  GLU B O   1 
ATOM   5269  C  CB  . GLU D 1 19  ? 193.653 131.145 125.054 1.00 121.99 ? 12  GLU B CB  1 
ATOM   5270  C  CG  . GLU D 1 19  ? 194.495 130.817 126.279 1.00 121.99 ? 12  GLU B CG  1 
ATOM   5271  C  CD  . GLU D 1 19  ? 194.231 131.763 127.434 1.00 121.99 ? 12  GLU B CD  1 
ATOM   5272  O  OE1 . GLU D 1 19  ? 193.396 132.679 127.278 1.00 121.99 ? 12  GLU B OE1 1 
ATOM   5273  O  OE2 . GLU D 1 19  ? 194.861 131.590 128.499 1.00 121.99 ? 12  GLU B OE2 1 
ATOM   5274  N  N   . GLN D 1 20  ? 192.281 128.341 124.705 1.00 117.64 ? 13  GLN B N   1 
ATOM   5275  C  CA  . GLN D 1 20  ? 191.958 127.020 125.226 1.00 117.64 ? 13  GLN B CA  1 
ATOM   5276  C  C   . GLN D 1 20  ? 190.642 126.561 124.620 1.00 117.64 ? 13  GLN B C   1 
ATOM   5277  O  O   . GLN D 1 20  ? 189.811 127.396 124.245 1.00 117.64 ? 13  GLN B O   1 
ATOM   5278  C  CB  . GLN D 1 20  ? 191.871 127.026 126.762 1.00 117.64 ? 13  GLN B CB  1 
ATOM   5279  C  CG  . GLN D 1 20  ? 190.537 127.495 127.342 1.00 117.64 ? 13  GLN B CG  1 
ATOM   5280  C  CD  . GLN D 1 20  ? 190.167 128.919 126.954 1.00 117.64 ? 13  GLN B CD  1 
ATOM   5281  O  OE1 . GLN D 1 20  ? 190.987 129.673 126.426 1.00 117.64 ? 13  GLN B OE1 1 
ATOM   5282  N  NE2 . GLN D 1 20  ? 188.921 129.293 127.219 1.00 117.64 ? 13  GLN B NE2 1 
ATOM   5283  N  N   . PRO D 1 21  ? 190.427 125.253 124.499 1.00 110.09 ? 14  PRO B N   1 
ATOM   5284  C  CA  . PRO D 1 21  ? 189.145 124.762 123.985 1.00 110.09 ? 14  PRO B CA  1 
ATOM   5285  C  C   . PRO D 1 21  ? 188.013 125.033 124.963 1.00 110.09 ? 14  PRO B C   1 
ATOM   5286  O  O   . PRO D 1 21  ? 188.214 125.181 126.170 1.00 110.09 ? 14  PRO B O   1 
ATOM   5287  C  CB  . PRO D 1 21  ? 189.382 123.258 123.810 1.00 110.09 ? 14  PRO B CB  1 
ATOM   5288  C  CG  . PRO D 1 21  ? 190.482 122.939 124.762 1.00 110.09 ? 14  PRO B CG  1 
ATOM   5289  C  CD  . PRO D 1 21  ? 191.363 124.153 124.790 1.00 110.09 ? 14  PRO B CD  1 
ATOM   5290  N  N   . THR D 1 22  ? 186.803 125.099 124.416 1.00 101.87 ? 15  THR B N   1 
ATOM   5291  C  CA  . THR D 1 22  ? 185.612 125.448 125.176 1.00 101.87 ? 15  THR B CA  1 
ATOM   5292  C  C   . THR D 1 22  ? 184.619 124.296 125.160 1.00 101.87 ? 15  THR B C   1 
ATOM   5293  O  O   . THR D 1 22  ? 184.364 123.698 124.111 1.00 101.87 ? 15  THR B O   1 
ATOM   5294  C  CB  . THR D 1 22  ? 184.948 126.708 124.612 1.00 101.87 ? 15  THR B CB  1 
ATOM   5295  O  OG1 . THR D 1 22  ? 185.934 127.733 124.438 1.00 101.87 ? 15  THR B OG1 1 
ATOM   5296  C  CG2 . THR D 1 22  ? 183.866 127.210 125.554 1.00 101.87 ? 15  THR B CG2 1 
ATOM   5297  N  N   . HIS D 1 23  ? 184.063 123.992 126.328 1.00 99.72  ? 16  HIS B N   1 
ATOM   5298  C  CA  . HIS D 1 23  ? 183.014 122.993 126.476 1.00 99.72  ? 16  HIS B CA  1 
ATOM   5299  C  C   . HIS D 1 23  ? 181.688 123.704 126.704 1.00 99.72  ? 16  HIS B C   1 
ATOM   5300  O  O   . HIS D 1 23  ? 181.590 124.576 127.575 1.00 99.72  ? 16  HIS B O   1 
ATOM   5301  C  CB  . HIS D 1 23  ? 183.311 122.046 127.642 1.00 99.72  ? 16  HIS B CB  1 
ATOM   5302  C  CG  . HIS D 1 23  ? 184.365 121.027 127.343 1.00 99.72  ? 16  HIS B CG  1 
ATOM   5303  N  ND1 . HIS D 1 23  ? 184.092 119.679 127.258 1.00 99.72  ? 16  HIS B ND1 1 
ATOM   5304  C  CD2 . HIS D 1 23  ? 185.693 121.157 127.117 1.00 99.72  ? 16  HIS B CD2 1 
ATOM   5305  C  CE1 . HIS D 1 23  ? 185.207 119.023 126.988 1.00 99.72  ? 16  HIS B CE1 1 
ATOM   5306  N  NE2 . HIS D 1 23  ? 186.193 119.897 126.897 1.00 99.72  ? 16  HIS B NE2 1 
ATOM   5307  N  N   . ALA D 1 24  ? 180.674 123.338 125.924 1.00 85.43  ? 17  ALA B N   1 
ATOM   5308  C  CA  . ALA D 1 24  ? 179.369 123.972 126.013 1.00 85.43  ? 17  ALA B CA  1 
ATOM   5309  C  C   . ALA D 1 24  ? 178.283 122.944 125.743 1.00 85.43  ? 17  ALA B C   1 
ATOM   5310  O  O   . ALA D 1 24  ? 178.518 121.914 125.107 1.00 85.43  ? 17  ALA B O   1 
ATOM   5311  C  CB  . ALA D 1 24  ? 179.244 125.144 125.034 1.00 85.43  ? 17  ALA B CB  1 
ATOM   5312  N  N   . VAL D 1 25  ? 177.083 123.240 126.234 1.00 77.67  ? 18  VAL B N   1 
ATOM   5313  C  CA  . VAL D 1 25  ? 175.919 122.376 126.071 1.00 77.67  ? 18  VAL B CA  1 
ATOM   5314  C  C   . VAL D 1 25  ? 174.929 123.066 125.144 1.00 77.67  ? 18  VAL B C   1 
ATOM   5315  O  O   . VAL D 1 25  ? 174.540 124.216 125.378 1.00 77.67  ? 18  VAL B O   1 
ATOM   5316  C  CB  . VAL D 1 25  ? 175.273 122.036 127.426 1.00 77.67  ? 18  VAL B CB  1 
ATOM   5317  C  CG1 . VAL D 1 25  ? 175.060 123.292 128.258 1.00 77.67  ? 18  VAL B CG1 1 
ATOM   5318  C  CG2 . VAL D 1 25  ? 173.957 121.311 127.212 1.00 77.67  ? 18  VAL B CG2 1 
ATOM   5319  N  N   . CYS D 1 26  ? 174.534 122.368 124.083 1.00 79.55  ? 19  CYS B N   1 
ATOM   5320  C  CA  . CYS D 1 26  ? 173.576 122.878 123.110 1.00 79.55  ? 19  CYS B CA  1 
ATOM   5321  C  C   . CYS D 1 26  ? 172.305 122.044 123.201 1.00 79.55  ? 19  CYS B C   1 
ATOM   5322  O  O   . CYS D 1 26  ? 172.289 120.884 122.779 1.00 79.55  ? 19  CYS B O   1 
ATOM   5323  C  CB  . CYS D 1 26  ? 174.159 122.838 121.697 1.00 79.55  ? 19  CYS B CB  1 
ATOM   5324  S  SG  . CYS D 1 26  ? 173.093 123.526 120.413 1.00 79.55  ? 19  CYS B SG  1 
ATOM   5325  N  N   . VAL D 1 27  ? 171.250 122.634 123.751 1.00 70.20  ? 20  VAL B N   1 
ATOM   5326  C  CA  . VAL D 1 27  ? 169.985 121.938 123.949 1.00 70.20  ? 20  VAL B CA  1 
ATOM   5327  C  C   . VAL D 1 27  ? 169.260 121.849 122.615 1.00 70.20  ? 20  VAL B C   1 
ATOM   5328  O  O   . VAL D 1 27  ? 169.141 122.848 121.897 1.00 70.20  ? 20  VAL B O   1 
ATOM   5329  C  CB  . VAL D 1 27  ? 169.121 122.652 124.998 1.00 70.20  ? 20  VAL B CB  1 
ATOM   5330  C  CG1 . VAL D 1 27  ? 167.912 121.806 125.344 1.00 70.20  ? 20  VAL B CG1 1 
ATOM   5331  C  CG2 . VAL D 1 27  ? 169.938 122.954 126.239 1.00 70.20  ? 20  VAL B CG2 1 
ATOM   5332  N  N   . LEU D 1 28  ? 168.782 120.654 122.282 1.00 77.81  ? 21  LEU B N   1 
ATOM   5333  C  CA  . LEU D 1 28  ? 168.079 120.454 121.023 1.00 77.81  ? 21  LEU B CA  1 
ATOM   5334  C  C   . LEU D 1 28  ? 166.770 121.236 121.030 1.00 77.81  ? 21  LEU B C   1 
ATOM   5335  O  O   . LEU D 1 28  ? 166.011 121.189 122.002 1.00 77.81  ? 21  LEU B O   1 
ATOM   5336  C  CB  . LEU D 1 28  ? 167.814 118.965 120.800 1.00 77.81  ? 21  LEU B CB  1 
ATOM   5337  C  CG  . LEU D 1 28  ? 167.214 118.505 119.470 1.00 77.81  ? 21  LEU B CG  1 
ATOM   5338  C  CD1 . LEU D 1 28  ? 167.647 119.399 118.315 1.00 77.81  ? 21  LEU B CD1 1 
ATOM   5339  C  CD2 . LEU D 1 28  ? 167.590 117.058 119.198 1.00 77.81  ? 21  LEU B CD2 1 
ATOM   5340  N  N   . GLY D 1 29  ? 166.508 121.955 119.941 1.00 83.32  ? 22  GLY B N   1 
ATOM   5341  C  CA  . GLY D 1 29  ? 165.345 122.811 119.828 1.00 83.32  ? 22  GLY B CA  1 
ATOM   5342  C  C   . GLY D 1 29  ? 165.620 124.274 120.093 1.00 83.32  ? 22  GLY B C   1 
ATOM   5343  O  O   . GLY D 1 29  ? 164.674 125.072 120.102 1.00 83.32  ? 22  GLY B O   1 
ATOM   5344  N  N   . THR D 1 30  ? 166.876 124.653 120.314 1.00 88.37  ? 23  THR B N   1 
ATOM   5345  C  CA  . THR D 1 30  ? 167.252 126.031 120.596 1.00 88.37  ? 23  THR B CA  1 
ATOM   5346  C  C   . THR D 1 30  ? 168.333 126.464 119.615 1.00 88.37  ? 23  THR B C   1 
ATOM   5347  O  O   . THR D 1 30  ? 169.327 125.755 119.430 1.00 88.37  ? 23  THR B O   1 
ATOM   5348  C  CB  . THR D 1 30  ? 167.747 126.175 122.039 1.00 88.37  ? 23  THR B CB  1 
ATOM   5349  O  OG1 . THR D 1 30  ? 166.625 126.281 122.922 1.00 88.37  ? 23  THR B OG1 1 
ATOM   5350  C  CG2 . THR D 1 30  ? 168.618 127.409 122.191 1.00 88.37  ? 23  THR B CG2 1 
ATOM   5351  N  N   . LEU D 1 31  ? 168.136 127.622 118.989 1.00 95.53  ? 24  LEU B N   1 
ATOM   5352  C  CA  . LEU D 1 31  ? 169.124 128.170 118.068 1.00 95.53  ? 24  LEU B CA  1 
ATOM   5353  C  C   . LEU D 1 31  ? 170.325 128.669 118.860 1.00 95.53  ? 24  LEU B C   1 
ATOM   5354  O  O   . LEU D 1 31  ? 170.165 129.363 119.870 1.00 95.53  ? 24  LEU B O   1 
ATOM   5355  C  CB  . LEU D 1 31  ? 168.526 129.301 117.234 1.00 95.53  ? 24  LEU B CB  1 
ATOM   5356  C  CG  . LEU D 1 31  ? 167.100 129.163 116.694 1.00 95.53  ? 24  LEU B CG  1 
ATOM   5357  C  CD1 . LEU D 1 31  ? 166.071 129.684 117.689 1.00 95.53  ? 24  LEU B CD1 1 
ATOM   5358  C  CD2 . LEU D 1 31  ? 166.968 129.882 115.359 1.00 95.53  ? 24  LEU B CD2 1 
ATOM   5359  N  N   . THR D 1 32  ? 171.526 128.321 118.406 1.00 100.17 ? 25  THR B N   1 
ATOM   5360  C  CA  . THR D 1 32  ? 172.763 128.696 119.080 1.00 100.17 ? 25  THR B CA  1 
ATOM   5361  C  C   . THR D 1 32  ? 173.646 129.469 118.113 1.00 100.17 ? 25  THR B C   1 
ATOM   5362  O  O   . THR D 1 32  ? 174.085 128.925 117.094 1.00 100.17 ? 25  THR B O   1 
ATOM   5363  C  CB  . THR D 1 32  ? 173.495 127.460 119.606 1.00 100.17 ? 25  THR B CB  1 
ATOM   5364  O  OG1 . THR D 1 32  ? 172.635 126.740 120.497 1.00 100.17 ? 25  THR B OG1 1 
ATOM   5365  C  CG2 . THR D 1 32  ? 174.751 127.865 120.348 1.00 100.17 ? 25  THR B CG2 1 
ATOM   5366  N  N   . GLN D 1 33  ? 173.919 130.729 118.436 1.00 100.84 ? 26  GLN B N   1 
ATOM   5367  C  CA  . GLN D 1 33  ? 174.757 131.577 117.603 1.00 100.84 ? 26  GLN B CA  1 
ATOM   5368  C  C   . GLN D 1 33  ? 176.166 131.654 118.176 1.00 100.84 ? 26  GLN B C   1 
ATOM   5369  O  O   . GLN D 1 33  ? 176.361 131.709 119.393 1.00 100.84 ? 26  GLN B O   1 
ATOM   5370  C  CB  . GLN D 1 33  ? 174.179 132.990 117.474 1.00 100.84 ? 26  GLN B CB  1 
ATOM   5371  C  CG  . GLN D 1 33  ? 172.860 133.110 116.710 1.00 100.84 ? 26  GLN B CG  1 
ATOM   5372  C  CD  . GLN D 1 33  ? 172.293 134.520 116.672 1.00 100.84 ? 26  GLN B CD  1 
ATOM   5373  O  OE1 . GLN D 1 33  ? 171.538 134.884 115.771 1.00 100.84 ? 26  GLN B OE1 1 
ATOM   5374  N  NE2 . GLN D 1 33  ? 172.658 135.324 117.664 1.00 100.84 ? 26  GLN B NE2 1 
ATOM   5375  N  N   . LEU D 1 34  ? 177.150 131.661 117.283 1.00 105.90 ? 27  LEU B N   1 
ATOM   5376  C  CA  . LEU D 1 34  ? 178.557 131.759 117.660 1.00 105.90 ? 27  LEU B CA  1 
ATOM   5377  C  C   . LEU D 1 34  ? 179.029 133.193 117.456 1.00 105.90 ? 27  LEU B C   1 
ATOM   5378  O  O   . LEU D 1 34  ? 179.025 133.700 116.329 1.00 105.90 ? 27  LEU B O   1 
ATOM   5379  C  CB  . LEU D 1 34  ? 179.419 130.788 116.857 1.00 105.90 ? 27  LEU B CB  1 
ATOM   5380  C  CG  . LEU D 1 34  ? 179.079 129.303 116.944 1.00 105.90 ? 27  LEU B CG  1 
ATOM   5381  C  CD1 . LEU D 1 34  ? 179.442 128.599 115.654 1.00 105.90 ? 27  LEU B CD1 1 
ATOM   5382  C  CD2 . LEU D 1 34  ? 179.809 128.678 118.115 1.00 105.90 ? 27  LEU B CD2 1 
ATOM   5383  N  N   . ASP D 1 35  ? 179.442 133.837 118.543 1.00 113.25 ? 28  ASP B N   1 
ATOM   5384  C  CA  . ASP D 1 35  ? 180.086 135.140 118.463 1.00 113.25 ? 28  ASP B CA  1 
ATOM   5385  C  C   . ASP D 1 35  ? 181.559 134.925 118.142 1.00 113.25 ? 28  ASP B C   1 
ATOM   5386  O  O   . ASP D 1 35  ? 182.288 134.314 118.931 1.00 113.25 ? 28  ASP B O   1 
ATOM   5387  C  CB  . ASP D 1 35  ? 179.912 135.901 119.775 1.00 113.25 ? 28  ASP B CB  1 
ATOM   5388  C  CG  . ASP D 1 35  ? 180.400 137.333 119.692 1.00 113.25 ? 28  ASP B CG  1 
ATOM   5389  O  OD1 . ASP D 1 35  ? 180.812 137.762 118.595 1.00 113.25 ? 28  ASP B OD1 1 
ATOM   5390  O  OD2 . ASP D 1 35  ? 180.373 138.032 120.727 1.00 113.25 ? 28  ASP B OD2 1 
ATOM   5391  N  N   . ILE D 1 36  ? 182.000 135.422 116.988 1.00 119.28 ? 29  ILE B N   1 
ATOM   5392  C  CA  . ILE D 1 36  ? 183.313 135.060 116.468 1.00 119.28 ? 29  ILE B CA  1 
ATOM   5393  C  C   . ILE D 1 36  ? 184.198 136.298 116.355 1.00 119.28 ? 29  ILE B C   1 
ATOM   5394  O  O   . ILE D 1 36  ? 185.243 136.277 115.695 1.00 119.28 ? 29  ILE B O   1 
ATOM   5395  C  CB  . ILE D 1 36  ? 183.164 134.333 115.116 1.00 119.28 ? 29  ILE B CB  1 
ATOM   5396  C  CG1 . ILE D 1 36  ? 184.436 133.556 114.767 1.00 119.28 ? 29  ILE B CG1 1 
ATOM   5397  C  CG2 . ILE D 1 36  ? 182.784 135.311 114.012 1.00 119.28 ? 29  ILE B CG2 1 
ATOM   5398  C  CD1 . ILE D 1 36  ? 184.391 132.898 113.420 1.00 119.28 ? 29  ILE B CD1 1 
ATOM   5399  N  N   . CYS D 1 37  ? 183.805 137.382 117.023 1.00 124.10 ? 30  CYS B N   1 
ATOM   5400  C  CA  . CYS D 1 37  ? 184.621 138.587 117.055 1.00 124.10 ? 30  CYS B CA  1 
ATOM   5401  C  C   . CYS D 1 37  ? 185.048 139.010 118.452 1.00 124.10 ? 30  CYS B C   1 
ATOM   5402  O  O   . CYS D 1 37  ? 185.907 139.890 118.570 1.00 124.10 ? 30  CYS B O   1 
ATOM   5403  C  CB  . CYS D 1 37  ? 183.886 139.762 116.389 1.00 124.10 ? 30  CYS B CB  1 
ATOM   5404  S  SG  . CYS D 1 37  ? 182.119 139.854 116.738 1.00 124.10 ? 30  CYS B SG  1 
ATOM   5405  N  N   . SER D 1 38  ? 184.479 138.418 119.504 1.00 121.16 ? 31  SER B N   1 
ATOM   5406  C  CA  . SER D 1 38  ? 184.854 138.805 120.861 1.00 121.16 ? 31  SER B CA  1 
ATOM   5407  C  C   . SER D 1 38  ? 186.315 138.477 121.150 1.00 121.16 ? 31  SER B C   1 
ATOM   5408  O  O   . SER D 1 38  ? 187.025 139.275 121.773 1.00 121.16 ? 31  SER B O   1 
ATOM   5409  C  CB  . SER D 1 38  ? 183.940 138.117 121.873 1.00 121.16 ? 31  SER B CB  1 
ATOM   5410  O  OG  . SER D 1 38  ? 182.580 138.415 121.615 1.00 121.16 ? 31  SER B OG  1 
ATOM   5411  N  N   . SER D 1 39  ? 186.782 137.309 120.709 1.00 128.95 ? 32  SER B N   1 
ATOM   5412  C  CA  . SER D 1 39  ? 188.139 136.859 120.990 1.00 128.95 ? 32  SER B CA  1 
ATOM   5413  C  C   . SER D 1 39  ? 188.980 136.704 119.728 1.00 128.95 ? 32  SER B C   1 
ATOM   5414  O  O   . SER D 1 39  ? 190.003 136.014 119.750 1.00 128.95 ? 32  SER B O   1 
ATOM   5415  C  CB  . SER D 1 39  ? 188.109 135.543 121.769 1.00 128.95 ? 32  SER B CB  1 
ATOM   5416  O  OG  . SER D 1 39  ? 189.418 135.129 122.121 1.00 128.95 ? 32  SER B OG  1 
ATOM   5417  N  N   . ALA D 1 40  ? 188.525 137.311 118.626 1.00 134.38 ? 33  ALA B N   1 
ATOM   5418  C  CA  . ALA D 1 40  ? 189.232 137.167 117.331 1.00 134.38 ? 33  ALA B CA  1 
ATOM   5419  C  C   . ALA D 1 40  ? 190.602 137.851 117.397 1.00 134.38 ? 33  ALA B C   1 
ATOM   5420  O  O   . ALA D 1 40  ? 190.710 138.902 118.061 1.00 134.38 ? 33  ALA B O   1 
ATOM   5421  C  CB  . ALA D 1 40  ? 188.385 137.741 116.221 1.00 134.38 ? 33  ALA B CB  1 
ATOM   5422  N  N   . PRO D 1 41  ? 191.647 137.309 116.733 1.00 143.50 ? 34  PRO B N   1 
ATOM   5423  C  CA  . PRO D 1 41  ? 192.965 137.952 116.709 1.00 143.50 ? 34  PRO B CA  1 
ATOM   5424  C  C   . PRO D 1 41  ? 192.863 139.382 116.162 1.00 143.50 ? 34  PRO B C   1 
ATOM   5425  O  O   . PRO D 1 41  ? 192.153 139.586 115.194 1.00 143.50 ? 34  PRO B O   1 
ATOM   5426  C  CB  . PRO D 1 41  ? 193.778 137.078 115.745 1.00 143.50 ? 34  PRO B CB  1 
ATOM   5427  C  CG  . PRO D 1 41  ? 193.162 135.703 115.880 1.00 143.50 ? 34  PRO B CG  1 
ATOM   5428  C  CD  . PRO D 1 41  ? 191.678 135.957 116.039 1.00 143.50 ? 34  PRO B CD  1 
ATOM   5429  N  N   . ASP D 1 42  ? 193.564 140.328 116.792 1.00 149.65 ? 35  ASP B N   1 
ATOM   5430  C  CA  . ASP D 1 42  ? 193.503 141.750 116.359 1.00 149.65 ? 35  ASP B CA  1 
ATOM   5431  C  C   . ASP D 1 42  ? 193.966 141.863 114.903 1.00 149.65 ? 35  ASP B C   1 
ATOM   5432  O  O   . ASP D 1 42  ? 193.248 142.502 114.109 1.00 149.65 ? 35  ASP B O   1 
ATOM   5433  C  CB  . ASP D 1 42  ? 194.326 142.647 117.287 1.00 149.65 ? 35  ASP B CB  1 
ATOM   5434  C  CG  . ASP D 1 42  ? 195.769 142.194 117.436 1.00 149.65 ? 35  ASP B CG  1 
ATOM   5435  O  OD1 . ASP D 1 42  ? 195.980 141.058 117.903 1.00 149.65 ? 35  ASP B OD1 1 
ATOM   5436  O  OD2 . ASP D 1 42  ? 196.668 142.979 117.074 1.00 149.65 ? 35  ASP B OD2 1 
ATOM   5437  N  N   . ASP D 1 43  ? 195.113 141.265 114.568 1.00 152.04 ? 36  ASP B N   1 
ATOM   5438  C  CA  . ASP D 1 43  ? 195.650 141.380 113.217 1.00 152.04 ? 36  ASP B CA  1 
ATOM   5439  C  C   . ASP D 1 43  ? 194.925 140.501 112.205 1.00 152.04 ? 36  ASP B C   1 
ATOM   5440  O  O   . ASP D 1 43  ? 195.302 140.505 111.029 1.00 152.04 ? 36  ASP B O   1 
ATOM   5441  C  CB  . ASP D 1 43  ? 197.142 141.036 113.219 1.00 152.04 ? 36  ASP B CB  1 
ATOM   5442  C  CG  . ASP D 1 43  ? 197.433 139.707 113.887 1.00 152.04 ? 36  ASP B CG  1 
ATOM   5443  O  OD1 . ASP D 1 43  ? 197.126 139.565 115.090 1.00 152.04 ? 36  ASP B OD1 1 
ATOM   5444  O  OD2 . ASP D 1 43  ? 197.969 138.804 113.211 1.00 152.04 ? 36  ASP B OD2 1 
ATOM   5445  N  N   . CYS D 1 44  ? 193.906 139.757 112.623 1.00 148.73 ? 37  CYS B N   1 
ATOM   5446  C  CA  . CYS D 1 44  ? 193.218 138.846 111.723 1.00 148.73 ? 37  CYS B CA  1 
ATOM   5447  C  C   . CYS D 1 44  ? 192.345 139.605 110.726 1.00 148.73 ? 37  CYS B C   1 
ATOM   5448  O  O   . CYS D 1 44  ? 191.941 140.749 110.950 1.00 148.73 ? 37  CYS B O   1 
ATOM   5449  C  CB  . CYS D 1 44  ? 192.361 137.860 112.511 1.00 148.73 ? 37  CYS B CB  1 
ATOM   5450  S  SG  . CYS D 1 44  ? 191.540 136.641 111.477 1.00 148.73 ? 37  CYS B SG  1 
ATOM   5451  N  N   . THR D 1 45  ? 192.054 138.939 109.606 1.00 147.17 ? 38  THR B N   1 
ATOM   5452  C  CA  . THR D 1 45  ? 191.214 139.507 108.556 1.00 147.17 ? 38  THR B CA  1 
ATOM   5453  C  C   . THR D 1 45  ? 190.122 138.576 108.043 1.00 147.17 ? 38  THR B C   1 
ATOM   5454  O  O   . THR D 1 45  ? 189.131 139.076 107.497 1.00 147.17 ? 38  THR B O   1 
ATOM   5455  C  CB  . THR D 1 45  ? 192.070 139.952 107.360 1.00 147.17 ? 38  THR B CB  1 
ATOM   5456  O  OG1 . THR D 1 45  ? 192.865 138.851 106.901 1.00 147.17 ? 38  THR B OG1 1 
ATOM   5457  C  CG2 . THR D 1 45  ? 192.978 141.111 107.745 1.00 147.17 ? 38  THR B CG2 1 
ATOM   5458  N  N   . SER D 1 46  ? 190.256 137.259 108.194 1.00 143.80 ? 39  SER B N   1 
ATOM   5459  C  CA  . SER D 1 46  ? 189.284 136.325 107.641 1.00 143.80 ? 39  SER B CA  1 
ATOM   5460  C  C   . SER D 1 46  ? 189.257 135.062 108.492 1.00 143.80 ? 39  SER B C   1 
ATOM   5461  O  O   . SER D 1 46  ? 190.138 134.829 109.325 1.00 143.80 ? 39  SER B O   1 
ATOM   5462  C  CB  . SER D 1 46  ? 189.601 135.989 106.180 1.00 143.80 ? 39  SER B CB  1 
ATOM   5463  O  OG  . SER D 1 46  ? 189.543 137.147 105.365 1.00 143.80 ? 39  SER B OG  1 
ATOM   5464  N  N   . PHE D 1 47  ? 188.231 134.240 108.270 1.00 137.59 ? 40  PHE B N   1 
ATOM   5465  C  CA  . PHE D 1 47  ? 188.061 133.014 109.037 1.00 137.59 ? 40  PHE B CA  1 
ATOM   5466  C  C   . PHE D 1 47  ? 187.402 131.948 108.174 1.00 137.59 ? 40  PHE B C   1 
ATOM   5467  O  O   . PHE D 1 47  ? 186.764 132.242 107.160 1.00 137.59 ? 40  PHE B O   1 
ATOM   5468  C  CB  . PHE D 1 47  ? 187.231 133.250 110.306 1.00 137.59 ? 40  PHE B CB  1 
ATOM   5469  C  CG  . PHE D 1 47  ? 185.767 133.484 110.043 1.00 137.59 ? 40  PHE B CG  1 
ATOM   5470  C  CD1 . PHE D 1 47  ? 185.291 134.758 109.789 1.00 137.59 ? 40  PHE B CD1 1 
ATOM   5471  C  CD2 . PHE D 1 47  ? 184.867 132.430 110.056 1.00 137.59 ? 40  PHE B CD2 1 
ATOM   5472  C  CE1 . PHE D 1 47  ? 183.948 134.976 109.551 1.00 137.59 ? 40  PHE B CE1 1 
ATOM   5473  C  CE2 . PHE D 1 47  ? 183.524 132.643 109.819 1.00 137.59 ? 40  PHE B CE2 1 
ATOM   5474  C  CZ  . PHE D 1 47  ? 183.064 133.918 109.566 1.00 137.59 ? 40  PHE B CZ  1 
ATOM   5475  N  N   . SER D 1 48  ? 187.565 130.697 108.603 1.00 135.15 ? 41  SER B N   1 
ATOM   5476  C  CA  . SER D 1 48  ? 186.915 129.550 107.985 1.00 135.15 ? 41  SER B CA  1 
ATOM   5477  C  C   . SER D 1 48  ? 186.443 128.600 109.078 1.00 135.15 ? 41  SER B C   1 
ATOM   5478  O  O   . SER D 1 48  ? 187.007 128.570 110.175 1.00 135.15 ? 41  SER B O   1 
ATOM   5479  C  CB  . SER D 1 48  ? 187.854 128.817 107.016 1.00 135.15 ? 41  SER B CB  1 
ATOM   5480  O  OG  . SER D 1 48  ? 187.904 129.471 105.761 1.00 135.15 ? 41  SER B OG  1 
ATOM   5481  N  N   . ILE D 1 49  ? 185.407 127.822 108.770 1.00 128.63 ? 42  ILE B N   1 
ATOM   5482  C  CA  . ILE D 1 49  ? 184.777 126.920 109.731 1.00 128.63 ? 42  ILE B CA  1 
ATOM   5483  C  C   . ILE D 1 49  ? 184.739 125.521 109.131 1.00 128.63 ? 42  ILE B C   1 
ATOM   5484  O  O   . ILE D 1 49  ? 184.360 125.357 107.965 1.00 128.63 ? 42  ILE B O   1 
ATOM   5485  C  CB  . ILE D 1 49  ? 183.354 127.372 110.100 1.00 128.63 ? 42  ILE B CB  1 
ATOM   5486  C  CG1 . ILE D 1 49  ? 183.297 128.888 110.308 1.00 128.63 ? 42  ILE B CG1 1 
ATOM   5487  C  CG2 . ILE D 1 49  ? 182.861 126.630 111.336 1.00 128.63 ? 42  ILE B CG2 1 
ATOM   5488  C  CD1 . ILE D 1 49  ? 183.672 129.334 111.701 1.00 128.63 ? 42  ILE B CD1 1 
ATOM   5489  N  N   . ASN D 1 50  ? 185.127 124.518 109.918 1.00 121.61 ? 43  ASN B N   1 
ATOM   5490  C  CA  . ASN D 1 50  ? 184.913 123.120 109.555 1.00 121.61 ? 43  ASN B CA  1 
ATOM   5491  C  C   . ASN D 1 50  ? 184.367 122.368 110.763 1.00 121.61 ? 43  ASN B C   1 
ATOM   5492  O  O   . ASN D 1 50  ? 184.941 122.433 111.856 1.00 121.61 ? 43  ASN B O   1 
ATOM   5493  C  CB  . ASN D 1 50  ? 186.196 122.470 109.028 1.00 121.61 ? 43  ASN B CB  1 
ATOM   5494  C  CG  . ASN D 1 50  ? 187.360 122.605 109.984 1.00 121.61 ? 43  ASN B CG  1 
ATOM   5495  O  OD1 . ASN D 1 50  ? 187.351 123.448 110.875 1.00 121.61 ? 43  ASN B OD1 1 
ATOM   5496  N  ND2 . ASN D 1 50  ? 188.374 121.768 109.802 1.00 121.61 ? 43  ASN B ND2 1 
ATOM   5497  N  N   . ALA D 1 51  ? 183.264 121.651 110.563 1.00 110.39 ? 44  ALA B N   1 
ATOM   5498  C  CA  . ALA D 1 51  ? 182.543 121.011 111.649 1.00 110.39 ? 44  ALA B CA  1 
ATOM   5499  C  C   . ALA D 1 51  ? 182.303 119.537 111.347 1.00 110.39 ? 44  ALA B C   1 
ATOM   5500  O  O   . ALA D 1 51  ? 182.414 119.085 110.204 1.00 110.39 ? 44  ALA B O   1 
ATOM   5501  C  CB  . ALA D 1 51  ? 181.204 121.710 111.910 1.00 110.39 ? 44  ALA B CB  1 
ATOM   5502  N  N   . SER D 1 52  ? 181.970 118.794 112.399 1.00 106.07 ? 45  SER B N   1 
ATOM   5503  C  CA  . SER D 1 52  ? 181.648 117.386 112.258 1.00 106.07 ? 45  SER B CA  1 
ATOM   5504  C  C   . SER D 1 52  ? 180.307 117.218 111.543 1.00 106.07 ? 45  SER B C   1 
ATOM   5505  O  O   . SER D 1 52  ? 179.453 118.108 111.592 1.00 106.07 ? 45  SER B O   1 
ATOM   5506  C  CB  . SER D 1 52  ? 181.600 116.714 113.629 1.00 106.07 ? 45  SER B CB  1 
ATOM   5507  O  OG  . SER D 1 52  ? 181.243 115.346 113.526 1.00 106.07 ? 45  SER B OG  1 
ATOM   5508  N  N   . PRO D 1 53  ? 180.099 116.085 110.865 1.00 104.89 ? 46  PRO B N   1 
ATOM   5509  C  CA  . PRO D 1 53  ? 178.823 115.884 110.156 1.00 104.89 ? 46  PRO B CA  1 
ATOM   5510  C  C   . PRO D 1 53  ? 177.612 115.859 111.072 1.00 104.89 ? 46  PRO B C   1 
ATOM   5511  O  O   . PRO D 1 53  ? 176.487 116.063 110.599 1.00 104.89 ? 46  PRO B O   1 
ATOM   5512  C  CB  . PRO D 1 53  ? 179.025 114.534 109.454 1.00 104.89 ? 46  PRO B CB  1 
ATOM   5513  C  CG  . PRO D 1 53  ? 180.504 114.377 109.346 1.00 104.89 ? 46  PRO B CG  1 
ATOM   5514  C  CD  . PRO D 1 53  ? 181.061 115.007 110.584 1.00 104.89 ? 46  PRO B CD  1 
ATOM   5515  N  N   . GLY D 1 54  ? 177.803 115.608 112.369 1.00 100.48 ? 47  GLY B N   1 
ATOM   5516  C  CA  . GLY D 1 54  ? 176.668 115.532 113.272 1.00 100.48 ? 47  GLY B CA  1 
ATOM   5517  C  C   . GLY D 1 54  ? 175.967 116.860 113.478 1.00 100.48 ? 47  GLY B C   1 
ATOM   5518  O  O   . GLY D 1 54  ? 174.797 116.895 113.868 1.00 100.48 ? 47  GLY B O   1 
ATOM   5519  N  N   . VAL D 1 55  ? 176.658 117.965 113.215 1.00 102.53 ? 48  VAL B N   1 
ATOM   5520  C  CA  . VAL D 1 55  ? 176.114 119.296 113.437 1.00 102.53 ? 48  VAL B CA  1 
ATOM   5521  C  C   . VAL D 1 55  ? 176.024 120.028 112.102 1.00 102.53 ? 48  VAL B C   1 
ATOM   5522  O  O   . VAL D 1 55  ? 176.692 119.681 111.123 1.00 102.53 ? 48  VAL B O   1 
ATOM   5523  C  CB  . VAL D 1 55  ? 176.960 120.094 114.452 1.00 102.53 ? 48  VAL B CB  1 
ATOM   5524  C  CG1 . VAL D 1 55  ? 178.140 120.757 113.764 1.00 102.53 ? 48  VAL B CG1 1 
ATOM   5525  C  CG2 . VAL D 1 55  ? 176.107 121.119 115.172 1.00 102.53 ? 48  VAL B CG2 1 
ATOM   5526  N  N   . VAL D 1 56  ? 175.177 121.054 112.067 1.00 105.69 ? 49  VAL B N   1 
ATOM   5527  C  CA  . VAL D 1 56  ? 174.960 121.871 110.879 1.00 105.69 ? 49  VAL B CA  1 
ATOM   5528  C  C   . VAL D 1 56  ? 175.351 123.304 111.206 1.00 105.69 ? 49  VAL B C   1 
ATOM   5529  O  O   . VAL D 1 56  ? 174.865 123.878 112.189 1.00 105.69 ? 49  VAL B O   1 
ATOM   5530  C  CB  . VAL D 1 56  ? 173.498 121.796 110.405 1.00 105.69 ? 49  VAL B CB  1 
ATOM   5531  C  CG1 . VAL D 1 56  ? 173.284 122.706 109.207 1.00 105.69 ? 49  VAL B CG1 1 
ATOM   5532  C  CG2 . VAL D 1 56  ? 173.123 120.363 110.067 1.00 105.69 ? 49  VAL B CG2 1 
ATOM   5533  N  N   . VAL D 1 57  ? 176.222 123.878 110.382 1.00 110.78 ? 50  VAL B N   1 
ATOM   5534  C  CA  . VAL D 1 57  ? 176.710 125.240 110.557 1.00 110.78 ? 50  VAL B CA  1 
ATOM   5535  C  C   . VAL D 1 57  ? 176.235 126.084 109.383 1.00 110.78 ? 50  VAL B C   1 
ATOM   5536  O  O   . VAL D 1 57  ? 176.377 125.687 108.220 1.00 110.78 ? 50  VAL B O   1 
ATOM   5537  C  CB  . VAL D 1 57  ? 178.247 125.274 110.688 1.00 110.78 ? 50  VAL B CB  1 
ATOM   5538  C  CG1 . VAL D 1 57  ? 178.900 124.481 109.567 1.00 110.78 ? 50  VAL B CG1 1 
ATOM   5539  C  CG2 . VAL D 1 57  ? 178.750 126.707 110.691 1.00 110.78 ? 50  VAL B CG2 1 
ATOM   5540  N  N   . ASP D 1 58  ? 175.654 127.242 109.688 1.00 120.53 ? 51  ASP B N   1 
ATOM   5541  C  CA  . ASP D 1 58  ? 175.123 128.141 108.670 1.00 120.53 ? 51  ASP B CA  1 
ATOM   5542  C  C   . ASP D 1 58  ? 175.716 129.527 108.862 1.00 120.53 ? 51  ASP B C   1 
ATOM   5543  O  O   . ASP D 1 58  ? 175.620 130.101 109.952 1.00 120.53 ? 51  ASP B O   1 
ATOM   5544  C  CB  . ASP D 1 58  ? 173.593 128.198 108.731 1.00 120.53 ? 51  ASP B CB  1 
ATOM   5545  C  CG  . ASP D 1 58  ? 173.025 129.383 107.978 1.00 120.53 ? 51  ASP B CG  1 
ATOM   5546  O  OD1 . ASP D 1 58  ? 173.265 129.483 106.756 1.00 120.53 ? 51  ASP B OD1 1 
ATOM   5547  O  OD2 . ASP D 1 58  ? 172.338 130.215 108.607 1.00 120.53 ? 51  ASP B OD2 1 
ATOM   5548  N  N   . ILE D 1 59  ? 176.326 130.060 107.807 1.00 127.15 ? 52  ILE B N   1 
ATOM   5549  C  CA  . ILE D 1 59  ? 176.843 131.424 107.802 1.00 127.15 ? 52  ILE B CA  1 
ATOM   5550  C  C   . ILE D 1 59  ? 175.749 132.306 107.214 1.00 127.15 ? 52  ILE B C   1 
ATOM   5551  O  O   . ILE D 1 59  ? 175.453 132.222 106.020 1.00 127.15 ? 52  ILE B O   1 
ATOM   5552  C  CB  . ILE D 1 59  ? 178.138 131.537 106.988 1.00 127.15 ? 52  ILE B CB  1 
ATOM   5553  C  CG1 . ILE D 1 59  ? 179.181 130.505 107.434 1.00 127.15 ? 52  ILE B CG1 1 
ATOM   5554  C  CG2 . ILE D 1 59  ? 178.710 132.941 107.097 1.00 127.15 ? 52  ILE B CG2 1 
ATOM   5555  C  CD1 . ILE D 1 59  ? 179.286 130.311 108.925 1.00 127.15 ? 52  ILE B CD1 1 
ATOM   5556  N  N   . ALA D 1 60  ? 175.144 133.160 108.040 1.00 130.75 ? 53  ALA B N   1 
ATOM   5557  C  CA  . ALA D 1 60  ? 173.952 133.901 107.627 1.00 130.75 ? 53  ALA B CA  1 
ATOM   5558  C  C   . ALA D 1 60  ? 174.302 135.375 107.452 1.00 130.75 ? 53  ALA B C   1 
ATOM   5559  O  O   . ALA D 1 60  ? 174.075 136.185 108.354 1.00 130.75 ? 53  ALA B O   1 
ATOM   5560  C  CB  . ALA D 1 60  ? 172.822 133.707 108.644 1.00 130.75 ? 53  ALA B CB  1 
ATOM   5561  N  N   . SER D 1 73  ? 183.829 130.088 101.129 1.00 141.44 ? 66  SER B N   1 
ATOM   5562  C  CA  . SER D 1 73  ? 184.773 129.468 102.051 1.00 141.44 ? 66  SER B CA  1 
ATOM   5563  C  C   . SER D 1 73  ? 185.232 130.462 103.112 1.00 141.44 ? 66  SER B C   1 
ATOM   5564  O  O   . SER D 1 73  ? 184.774 130.423 104.253 1.00 141.44 ? 66  SER B O   1 
ATOM   5565  C  CB  . SER D 1 73  ? 185.979 128.913 101.292 1.00 141.44 ? 66  SER B CB  1 
ATOM   5566  O  OG  . SER D 1 73  ? 186.651 129.939 100.582 1.00 141.44 ? 66  SER B OG  1 
ATOM   5567  N  N   . THR D 1 74  ? 186.143 131.351 102.728 1.00 143.44 ? 67  THR B N   1 
ATOM   5568  C  CA  . THR D 1 74  ? 186.643 132.366 103.643 1.00 143.44 ? 67  THR B CA  1 
ATOM   5569  C  C   . THR D 1 74  ? 185.670 133.534 103.721 1.00 143.44 ? 67  THR B C   1 
ATOM   5570  O  O   . THR D 1 74  ? 185.121 133.976 102.708 1.00 143.44 ? 67  THR B O   1 
ATOM   5571  C  CB  . THR D 1 74  ? 188.018 132.862 103.194 1.00 143.44 ? 67  THR B CB  1 
ATOM   5572  O  OG1 . THR D 1 74  ? 187.931 133.376 101.859 1.00 143.44 ? 67  THR B OG1 1 
ATOM   5573  C  CG2 . THR D 1 74  ? 189.031 131.727 103.231 1.00 143.44 ? 67  THR B CG2 1 
ATOM   5574  N  N   . TRP D 1 75  ? 185.456 134.032 104.935 1.00 141.91 ? 68  TRP B N   1 
ATOM   5575  C  CA  . TRP D 1 75  ? 184.546 135.138 105.178 1.00 141.91 ? 68  TRP B CA  1 
ATOM   5576  C  C   . TRP D 1 75  ? 185.224 136.189 106.043 1.00 141.91 ? 68  TRP B C   1 
ATOM   5577  O  O   . TRP D 1 75  ? 186.078 135.862 106.872 1.00 141.91 ? 68  TRP B O   1 
ATOM   5578  C  CB  . TRP D 1 75  ? 183.262 134.659 105.872 1.00 141.91 ? 68  TRP B CB  1 
ATOM   5579  C  CG  . TRP D 1 75  ? 182.377 133.809 105.009 1.00 141.91 ? 68  TRP B CG  1 
ATOM   5580  C  CD1 . TRP D 1 75  ? 182.674 132.586 104.484 1.00 141.91 ? 68  TRP B CD1 1 
ATOM   5581  C  CD2 . TRP D 1 75  ? 181.047 134.118 104.577 1.00 141.91 ? 68  TRP B CD2 1 
ATOM   5582  N  NE1 . TRP D 1 75  ? 181.613 132.115 103.750 1.00 141.91 ? 68  TRP B NE1 1 
ATOM   5583  C  CE2 . TRP D 1 75  ? 180.601 133.038 103.791 1.00 141.91 ? 68  TRP B CE2 1 
ATOM   5584  C  CE3 . TRP D 1 75  ? 180.191 135.205 104.777 1.00 141.91 ? 68  TRP B CE3 1 
ATOM   5585  C  CZ2 . TRP D 1 75  ? 179.338 133.012 103.206 1.00 141.91 ? 68  TRP B CZ2 1 
ATOM   5586  C  CZ3 . TRP D 1 75  ? 178.936 135.177 104.194 1.00 141.91 ? 68  TRP B CZ3 1 
ATOM   5587  C  CH2 . TRP D 1 75  ? 178.522 134.089 103.418 1.00 141.91 ? 68  TRP B CH2 1 
ATOM   5588  N  N   . PRO D 1 76  ? 184.868 137.459 105.867 1.00 142.45 ? 69  PRO B N   1 
ATOM   5589  C  CA  . PRO D 1 76  ? 185.410 138.501 106.746 1.00 142.45 ? 69  PRO B CA  1 
ATOM   5590  C  C   . PRO D 1 76  ? 184.859 138.376 108.156 1.00 142.45 ? 69  PRO B C   1 
ATOM   5591  O  O   . PRO D 1 76  ? 183.752 137.879 108.376 1.00 142.45 ? 69  PRO B O   1 
ATOM   5592  C  CB  . PRO D 1 76  ? 184.950 139.801 106.080 1.00 142.45 ? 69  PRO B CB  1 
ATOM   5593  C  CG  . PRO D 1 76  ? 183.721 139.420 105.331 1.00 142.45 ? 69  PRO B CG  1 
ATOM   5594  C  CD  . PRO D 1 76  ? 183.941 138.009 104.861 1.00 142.45 ? 69  PRO B CD  1 
ATOM   5595  N  N   . LEU D 1 77  ? 185.649 138.850 109.121 1.00 141.91 ? 70  LEU B N   1 
ATOM   5596  C  CA  . LEU D 1 77  ? 185.294 138.774 110.534 1.00 141.91 ? 70  LEU B CA  1 
ATOM   5597  C  C   . LEU D 1 77  ? 184.508 139.990 111.012 1.00 141.91 ? 70  LEU B C   1 
ATOM   5598  O  O   . LEU D 1 77  ? 184.526 140.305 112.210 1.00 141.91 ? 70  LEU B O   1 
ATOM   5599  C  CB  . LEU D 1 77  ? 186.555 138.566 111.376 1.00 141.91 ? 70  LEU B CB  1 
ATOM   5600  C  CG  . LEU D 1 77  ? 187.679 139.608 111.343 1.00 141.91 ? 70  LEU B CG  1 
ATOM   5601  C  CD1 . LEU D 1 77  ? 187.566 140.643 112.455 1.00 141.91 ? 70  LEU B CD1 1 
ATOM   5602  C  CD2 . LEU D 1 77  ? 189.023 138.906 111.410 1.00 141.91 ? 70  LEU B CD2 1 
ATOM   5603  N  N   . ASP D 1 78  ? 183.797 140.664 110.111 1.00 141.55 ? 71  ASP B N   1 
ATOM   5604  C  CA  . ASP D 1 78  ? 183.027 141.837 110.490 1.00 141.55 ? 71  ASP B CA  1 
ATOM   5605  C  C   . ASP D 1 78  ? 181.940 141.458 111.494 1.00 141.55 ? 71  ASP B C   1 
ATOM   5606  O  O   . ASP D 1 78  ? 181.401 140.348 111.448 1.00 141.55 ? 71  ASP B O   1 
ATOM   5607  C  CB  . ASP D 1 78  ? 182.398 142.479 109.256 1.00 141.55 ? 71  ASP B CB  1 
ATOM   5608  C  CG  . ASP D 1 78  ? 181.442 141.546 108.542 1.00 141.55 ? 71  ASP B CG  1 
ATOM   5609  O  OD1 . ASP D 1 78  ? 181.889 140.475 108.081 1.00 141.55 ? 71  ASP B OD1 1 
ATOM   5610  O  OD2 . ASP D 1 78  ? 180.243 141.882 108.445 1.00 141.55 ? 71  ASP B OD2 1 
ATOM   5611  N  N   . PRO D 1 79  ? 181.606 142.358 112.420 1.00 139.32 ? 72  PRO B N   1 
ATOM   5612  C  CA  . PRO D 1 79  ? 180.591 142.027 113.436 1.00 139.32 ? 72  PRO B CA  1 
ATOM   5613  C  C   . PRO D 1 79  ? 179.215 141.744 112.859 1.00 139.32 ? 72  PRO B C   1 
ATOM   5614  O  O   . PRO D 1 79  ? 178.400 141.104 113.536 1.00 139.32 ? 72  PRO B O   1 
ATOM   5615  C  CB  . PRO D 1 79  ? 180.573 143.274 114.332 1.00 139.32 ? 72  PRO B CB  1 
ATOM   5616  C  CG  . PRO D 1 79  ? 181.893 143.935 114.098 1.00 139.32 ? 72  PRO B CG  1 
ATOM   5617  C  CD  . PRO D 1 79  ? 182.215 143.677 112.659 1.00 139.32 ? 72  PRO B CD  1 
ATOM   5618  N  N   . GLY D 1 80  ? 178.926 142.206 111.641 1.00 137.22 ? 73  GLY B N   1 
ATOM   5619  C  CA  . GLY D 1 80  ? 177.605 141.989 111.076 1.00 137.22 ? 73  GLY B CA  1 
ATOM   5620  C  C   . GLY D 1 80  ? 177.290 140.524 110.834 1.00 137.22 ? 73  GLY B C   1 
ATOM   5621  O  O   . GLY D 1 80  ? 176.204 140.051 111.181 1.00 137.22 ? 73  GLY B O   1 
ATOM   5622  N  N   . VAL D 1 81  ? 178.236 139.785 110.250 1.00 134.02 ? 74  VAL B N   1 
ATOM   5623  C  CA  . VAL D 1 81  ? 177.994 138.390 109.899 1.00 134.02 ? 74  VAL B CA  1 
ATOM   5624  C  C   . VAL D 1 81  ? 177.776 137.564 111.162 1.00 134.02 ? 74  VAL B C   1 
ATOM   5625  O  O   . VAL D 1 81  ? 178.313 137.867 112.237 1.00 134.02 ? 74  VAL B O   1 
ATOM   5626  C  CB  . VAL D 1 81  ? 179.162 137.839 109.057 1.00 134.02 ? 74  VAL B CB  1 
ATOM   5627  C  CG1 . VAL D 1 81  ? 178.982 136.353 108.787 1.00 134.02 ? 74  VAL B CG1 1 
ATOM   5628  C  CG2 . VAL D 1 81  ? 179.304 138.612 107.753 1.00 134.02 ? 74  VAL B CG2 1 
ATOM   5629  N  N   . GLU D 1 82  ? 176.962 136.516 111.041 1.00 124.26 ? 75  GLU B N   1 
ATOM   5630  C  CA  . GLU D 1 82  ? 176.649 135.653 112.169 1.00 124.26 ? 75  GLU B CA  1 
ATOM   5631  C  C   . GLU D 1 82  ? 176.666 134.196 111.729 1.00 124.26 ? 75  GLU B C   1 
ATOM   5632  O  O   . GLU D 1 82  ? 176.499 133.872 110.548 1.00 124.26 ? 75  GLU B O   1 
ATOM   5633  C  CB  . GLU D 1 82  ? 175.292 136.010 112.793 1.00 124.26 ? 75  GLU B CB  1 
ATOM   5634  C  CG  . GLU D 1 82  ? 174.093 135.407 112.086 1.00 124.26 ? 75  GLU B CG  1 
ATOM   5635  C  CD  . GLU D 1 82  ? 172.793 135.706 112.806 1.00 124.26 ? 75  GLU B CD  1 
ATOM   5636  O  OE1 . GLU D 1 82  ? 172.842 136.042 114.009 1.00 124.26 ? 75  GLU B OE1 1 
ATOM   5637  O  OE2 . GLU D 1 82  ? 171.723 135.607 112.170 1.00 124.26 ? 75  GLU B OE2 1 
ATOM   5638  N  N   . VAL D 1 83  ? 176.886 133.318 112.705 1.00 114.89 ? 76  VAL B N   1 
ATOM   5639  C  CA  . VAL D 1 83  ? 177.018 131.884 112.484 1.00 114.89 ? 76  VAL B CA  1 
ATOM   5640  C  C   . VAL D 1 83  ? 176.037 131.165 113.398 1.00 114.89 ? 76  VAL B C   1 
ATOM   5641  O  O   . VAL D 1 83  ? 176.018 131.414 114.609 1.00 114.89 ? 76  VAL B O   1 
ATOM   5642  C  CB  . VAL D 1 83  ? 178.454 131.396 112.753 1.00 114.89 ? 76  VAL B CB  1 
ATOM   5643  C  CG1 . VAL D 1 83  ? 178.580 129.919 112.435 1.00 114.89 ? 76  VAL B CG1 1 
ATOM   5644  C  CG2 . VAL D 1 83  ? 179.457 132.218 111.961 1.00 114.89 ? 76  VAL B CG2 1 
ATOM   5645  N  N   . THR D 1 84  ? 175.237 130.270 112.827 1.00 109.35 ? 77  THR B N   1 
ATOM   5646  C  CA  . THR D 1 84  ? 174.249 129.506 113.574 1.00 109.35 ? 77  THR B CA  1 
ATOM   5647  C  C   . THR D 1 84  ? 174.605 128.025 113.551 1.00 109.35 ? 77  THR B C   1 
ATOM   5648  O  O   . THR D 1 84  ? 175.058 127.500 112.528 1.00 109.35 ? 77  THR B O   1 
ATOM   5649  C  CB  . THR D 1 84  ? 172.845 129.707 113.001 1.00 109.35 ? 77  THR B CB  1 
ATOM   5650  O  OG1 . THR D 1 84  ? 172.727 129.002 111.760 1.00 109.35 ? 77  THR B OG1 1 
ATOM   5651  C  CG2 . THR D 1 84  ? 172.575 131.184 112.766 1.00 109.35 ? 77  THR B CG2 1 
ATOM   5652  N  N   . LEU D 1 85  ? 174.391 127.356 114.682 1.00 97.15  ? 78  LEU B N   1 
ATOM   5653  C  CA  . LEU D 1 85  ? 174.715 125.948 114.853 1.00 97.15  ? 78  LEU B CA  1 
ATOM   5654  C  C   . LEU D 1 85  ? 173.452 125.194 115.240 1.00 97.15  ? 78  LEU B C   1 
ATOM   5655  O  O   . LEU D 1 85  ? 172.710 125.637 116.123 1.00 97.15  ? 78  LEU B O   1 
ATOM   5656  C  CB  . LEU D 1 85  ? 175.792 125.763 115.922 1.00 97.15  ? 78  LEU B CB  1 
ATOM   5657  C  CG  . LEU D 1 85  ? 176.798 124.635 115.707 1.00 97.15  ? 78  LEU B CG  1 
ATOM   5658  C  CD1 . LEU D 1 85  ? 177.379 124.703 114.307 1.00 97.15  ? 78  LEU B CD1 1 
ATOM   5659  C  CD2 . LEU D 1 85  ? 177.899 124.696 116.749 1.00 97.15  ? 78  LEU B CD2 1 
ATOM   5660  N  N   . THR D 1 86  ? 173.207 124.063 114.581 1.00 98.79  ? 79  THR B N   1 
ATOM   5661  C  CA  . THR D 1 86  ? 172.015 123.262 114.830 1.00 98.79  ? 79  THR B CA  1 
ATOM   5662  C  C   . THR D 1 86  ? 172.395 121.792 114.932 1.00 98.79  ? 79  THR B C   1 
ATOM   5663  O  O   . THR D 1 86  ? 173.086 121.263 114.056 1.00 98.79  ? 79  THR B O   1 
ATOM   5664  C  CB  . THR D 1 86  ? 170.974 123.465 113.723 1.00 98.79  ? 79  THR B CB  1 
ATOM   5665  O  OG1 . THR D 1 86  ? 170.431 124.787 113.813 1.00 98.79  ? 79  THR B OG1 1 
ATOM   5666  C  CG2 . THR D 1 86  ? 169.845 122.456 113.858 1.00 98.79  ? 79  THR B CG2 1 
ATOM   5667  N  N   . MET D 1 87  ? 171.938 121.137 115.993 1.00 93.81  ? 80  MET B N   1 
ATOM   5668  C  CA  . MET D 1 87  ? 172.191 119.720 116.204 1.00 93.81  ? 80  MET B CA  1 
ATOM   5669  C  C   . MET D 1 87  ? 170.970 118.910 115.789 1.00 93.81  ? 80  MET B C   1 
ATOM   5670  O  O   . MET D 1 87  ? 169.836 119.387 115.883 1.00 93.81  ? 80  MET B O   1 
ATOM   5671  C  CB  . MET D 1 87  ? 172.543 119.439 117.664 1.00 93.81  ? 80  MET B CB  1 
ATOM   5672  C  CG  . MET D 1 87  ? 173.964 119.821 118.021 1.00 93.81  ? 80  MET B CG  1 
ATOM   5673  S  SD  . MET D 1 87  ? 175.152 118.573 117.501 1.00 93.81  ? 80  MET B SD  1 
ATOM   5674  C  CE  . MET D 1 87  ? 175.518 117.796 119.064 1.00 93.81  ? 80  MET B CE  1 
ATOM   5675  N  N   . LYS D 1 88  ? 171.209 117.682 115.329 1.00 89.67  ? 81  LYS B N   1 
ATOM   5676  C  CA  . LYS D 1 88  ? 170.140 116.837 114.810 1.00 89.67  ? 81  LYS B CA  1 
ATOM   5677  C  C   . LYS D 1 88  ? 169.737 115.710 115.749 1.00 89.67  ? 81  LYS B C   1 
ATOM   5678  O  O   . LYS D 1 88  ? 168.552 115.367 115.807 1.00 89.67  ? 81  LYS B O   1 
ATOM   5679  C  CB  . LYS D 1 88  ? 170.547 116.239 113.460 1.00 89.67  ? 81  LYS B CB  1 
ATOM   5680  C  CG  . LYS D 1 88  ? 171.374 117.170 112.591 1.00 89.67  ? 81  LYS B CG  1 
ATOM   5681  C  CD  . LYS D 1 88  ? 171.549 116.608 111.189 1.00 89.67  ? 81  LYS B CD  1 
ATOM   5682  C  CE  . LYS D 1 88  ? 172.429 115.369 111.192 1.00 89.67  ? 81  LYS B CE  1 
ATOM   5683  N  NZ  . LYS D 1 88  ? 173.845 115.695 111.513 1.00 89.67  ? 81  LYS B NZ  1 
ATOM   5684  N  N   . ALA D 1 89  ? 170.679 115.126 116.485 1.00 82.29  ? 82  ALA B N   1 
ATOM   5685  C  CA  . ALA D 1 89  ? 170.387 113.979 117.333 1.00 82.29  ? 82  ALA B CA  1 
ATOM   5686  C  C   . ALA D 1 89  ? 170.990 114.193 118.713 1.00 82.29  ? 82  ALA B C   1 
ATOM   5687  O  O   . ALA D 1 89  ? 171.964 114.928 118.884 1.00 82.29  ? 82  ALA B O   1 
ATOM   5688  C  CB  . ALA D 1 89  ? 170.916 112.676 116.722 1.00 82.29  ? 82  ALA B CB  1 
ATOM   5689  N  N   . ALA D 1 90  ? 170.392 113.532 119.702 1.00 77.48  ? 83  ALA B N   1 
ATOM   5690  C  CA  . ALA D 1 90  ? 170.874 113.628 121.070 1.00 77.48  ? 83  ALA B CA  1 
ATOM   5691  C  C   . ALA D 1 90  ? 172.245 112.978 121.206 1.00 77.48  ? 83  ALA B C   1 
ATOM   5692  O  O   . ALA D 1 90  ? 172.603 112.062 120.462 1.00 77.48  ? 83  ALA B O   1 
ATOM   5693  C  CB  . ALA D 1 90  ? 169.888 112.969 122.033 1.00 77.48  ? 83  ALA B CB  1 
ATOM   5694  N  N   . SER D 1 91  ? 173.017 113.465 122.173 1.00 78.77  ? 84  SER B N   1 
ATOM   5695  C  CA  . SER D 1 91  ? 174.368 112.969 122.388 1.00 78.77  ? 84  SER B CA  1 
ATOM   5696  C  C   . SER D 1 91  ? 174.353 111.673 123.185 1.00 78.77  ? 84  SER B C   1 
ATOM   5697  O  O   . SER D 1 91  ? 173.608 111.533 124.158 1.00 78.77  ? 84  SER B O   1 
ATOM   5698  C  CB  . SER D 1 91  ? 175.207 114.016 123.116 1.00 78.77  ? 84  SER B CB  1 
ATOM   5699  O  OG  . SER D 1 91  ? 175.214 115.243 122.411 1.00 78.77  ? 84  SER B OG  1 
ATOM   5700  N  N   . GLY D 1 92  ? 175.183 110.723 122.762 1.00 81.78  ? 85  GLY B N   1 
ATOM   5701  C  CA  . GLY D 1 92  ? 175.344 109.482 123.492 1.00 81.78  ? 85  GLY B CA  1 
ATOM   5702  C  C   . GLY D 1 92  ? 176.471 109.545 124.500 1.00 81.78  ? 85  GLY B C   1 
ATOM   5703  O  O   . GLY D 1 92  ? 176.560 108.704 125.400 1.00 81.78  ? 85  GLY B O   1 
ATOM   5704  N  N   . SER D 1 93  ? 177.342 110.542 124.361 1.00 83.17  ? 86  SER B N   1 
ATOM   5705  C  CA  . SER D 1 93  ? 178.466 110.715 125.268 1.00 83.17  ? 86  SER B CA  1 
ATOM   5706  C  C   . SER D 1 93  ? 178.850 112.186 125.306 1.00 83.17  ? 86  SER B C   1 
ATOM   5707  O  O   . SER D 1 93  ? 178.512 112.959 124.405 1.00 83.17  ? 86  SER B O   1 
ATOM   5708  C  CB  . SER D 1 93  ? 179.665 109.856 124.852 1.00 83.17  ? 86  SER B CB  1 
ATOM   5709  O  OG  . SER D 1 93  ? 180.159 110.250 123.585 1.00 83.17  ? 86  SER B OG  1 
ATOM   5710  N  N   . THR D 1 94  ? 179.565 112.563 126.361 1.00 86.51  ? 87  THR B N   1 
ATOM   5711  C  CA  . THR D 1 94  ? 179.949 113.954 126.545 1.00 86.51  ? 87  THR B CA  1 
ATOM   5712  C  C   . THR D 1 94  ? 181.013 114.366 125.531 1.00 86.51  ? 87  THR B C   1 
ATOM   5713  O  O   . THR D 1 94  ? 181.971 113.635 125.267 1.00 86.51  ? 87  THR B O   1 
ATOM   5714  C  CB  . THR D 1 94  ? 180.472 114.181 127.963 1.00 86.51  ? 87  THR B CB  1 
ATOM   5715  O  OG1 . THR D 1 94  ? 179.592 113.552 128.904 1.00 86.51  ? 87  THR B OG1 1 
ATOM   5716  C  CG2 . THR D 1 94  ? 180.549 115.668 128.272 1.00 86.51  ? 87  THR B CG2 1 
ATOM   5717  N  N   . GLY D 1 95  ? 180.833 115.558 124.964 1.00 90.99  ? 88  GLY B N   1 
ATOM   5718  C  CA  . GLY D 1 95  ? 181.797 116.128 124.045 1.00 90.99  ? 88  GLY B CA  1 
ATOM   5719  C  C   . GLY D 1 95  ? 182.021 115.308 122.793 1.00 90.99  ? 88  GLY B C   1 
ATOM   5720  O  O   . GLY D 1 95  ? 183.167 115.070 122.402 1.00 90.99  ? 88  GLY B O   1 
ATOM   5721  N  N   . ASP D 1 96  ? 180.941 114.862 122.157 1.00 90.41  ? 89  ASP B N   1 
ATOM   5722  C  CA  . ASP D 1 96  ? 181.072 113.996 120.995 1.00 90.41  ? 89  ASP B CA  1 
ATOM   5723  C  C   . ASP D 1 96  ? 181.046 114.743 119.666 1.00 90.41  ? 89  ASP B C   1 
ATOM   5724  O  O   . ASP D 1 96  ? 181.183 114.100 118.620 1.00 90.41  ? 89  ASP B O   1 
ATOM   5725  C  CB  . ASP D 1 96  ? 179.991 112.901 121.027 1.00 90.41  ? 89  ASP B CB  1 
ATOM   5726  C  CG  . ASP D 1 96  ? 178.606 113.407 120.653 1.00 90.41  ? 89  ASP B CG  1 
ATOM   5727  O  OD1 . ASP D 1 96  ? 178.408 113.932 119.540 1.00 90.41  ? 89  ASP B OD1 1 
ATOM   5728  O  OD2 . ASP D 1 96  ? 177.698 113.264 121.492 1.00 90.41  ? 89  ASP B OD2 1 
ATOM   5729  N  N   . GLN D 1 97  ? 180.874 116.065 119.662 1.00 94.76  ? 90  GLN B N   1 
ATOM   5730  C  CA  . GLN D 1 97  ? 181.022 116.822 118.426 1.00 94.76  ? 90  GLN B CA  1 
ATOM   5731  C  C   . GLN D 1 97  ? 182.124 117.859 118.572 1.00 94.76  ? 90  GLN B C   1 
ATOM   5732  O  O   . GLN D 1 97  ? 182.339 118.407 119.652 1.00 94.76  ? 90  GLN B O   1 
ATOM   5733  C  CB  . GLN D 1 97  ? 179.715 117.505 118.009 1.00 94.76  ? 90  GLN B CB  1 
ATOM   5734  C  CG  . GLN D 1 97  ? 178.506 116.582 117.921 1.00 94.76  ? 90  GLN B CG  1 
ATOM   5735  C  CD  . GLN D 1 97  ? 178.602 115.505 116.843 1.00 94.76  ? 90  GLN B CD  1 
ATOM   5736  O  OE1 . GLN D 1 97  ? 179.677 115.195 116.330 1.00 94.76  ? 90  GLN B OE1 1 
ATOM   5737  N  NE2 . GLN D 1 97  ? 177.457 114.928 116.499 1.00 94.76  ? 90  GLN B NE2 1 
ATOM   5738  N  N   . LYS D 1 98  ? 182.819 118.124 117.469 1.00 99.19  ? 91  LYS B N   1 
ATOM   5739  C  CA  . LYS D 1 98  ? 183.899 119.100 117.459 1.00 99.19  ? 91  LYS B CA  1 
ATOM   5740  C  C   . LYS D 1 98  ? 183.728 120.040 116.278 1.00 99.19  ? 91  LYS B C   1 
ATOM   5741  O  O   . LYS D 1 98  ? 183.407 119.608 115.168 1.00 99.19  ? 91  LYS B O   1 
ATOM   5742  C  CB  . LYS D 1 98  ? 185.271 118.418 117.395 1.00 99.19  ? 91  LYS B CB  1 
ATOM   5743  C  CG  . LYS D 1 98  ? 185.387 117.343 116.329 1.00 99.19  ? 91  LYS B CG  1 
ATOM   5744  C  CD  . LYS D 1 98  ? 186.771 116.717 116.328 1.00 99.19  ? 91  LYS B CD  1 
ATOM   5745  C  CE  . LYS D 1 98  ? 187.845 117.757 116.057 1.00 99.19  ? 91  LYS B CE  1 
ATOM   5746  N  NZ  . LYS D 1 98  ? 187.636 118.443 114.752 1.00 99.19  ? 91  LYS B NZ  1 
ATOM   5747  N  N   . VAL D 1 99  ? 183.937 121.330 116.530 1.00 106.89 ? 92  VAL B N   1 
ATOM   5748  C  CA  . VAL D 1 99  ? 183.910 122.361 115.499 1.00 106.89 ? 92  VAL B CA  1 
ATOM   5749  C  C   . VAL D 1 99  ? 185.213 123.140 115.589 1.00 106.89 ? 92  VAL B C   1 
ATOM   5750  O  O   . VAL D 1 99  ? 185.628 123.533 116.686 1.00 106.89 ? 92  VAL B O   1 
ATOM   5751  C  CB  . VAL D 1 99  ? 182.702 123.304 115.659 1.00 106.89 ? 92  VAL B CB  1 
ATOM   5752  C  CG1 . VAL D 1 99  ? 182.749 124.411 114.621 1.00 106.89 ? 92  VAL B CG1 1 
ATOM   5753  C  CG2 . VAL D 1 99  ? 181.403 122.525 115.550 1.00 106.89 ? 92  VAL B CG2 1 
ATOM   5754  N  N   . GLN D 1 100 ? 185.863 123.354 114.447 1.00 121.88 ? 93  GLN B N   1 
ATOM   5755  C  CA  . GLN D 1 100 ? 187.136 124.053 114.395 1.00 121.88 ? 93  GLN B CA  1 
ATOM   5756  C  C   . GLN D 1 100 ? 186.997 125.308 113.546 1.00 121.88 ? 93  GLN B C   1 
ATOM   5757  O  O   . GLN D 1 100 ? 186.323 125.305 112.506 1.00 121.88 ? 93  GLN B O   1 
ATOM   5758  C  CB  . GLN D 1 100 ? 188.242 123.145 113.839 1.00 121.88 ? 93  GLN B CB  1 
ATOM   5759  C  CG  . GLN D 1 100 ? 189.580 123.837 113.634 1.00 121.88 ? 93  GLN B CG  1 
ATOM   5760  C  CD  . GLN D 1 100 ? 190.573 122.974 112.884 1.00 121.88 ? 93  GLN B CD  1 
ATOM   5761  O  OE1 . GLN D 1 100 ? 191.110 123.377 111.851 1.00 121.88 ? 93  GLN B OE1 1 
ATOM   5762  N  NE2 . GLN D 1 100 ? 190.826 121.777 113.401 1.00 121.88 ? 93  GLN B NE2 1 
ATOM   5763  N  N   . ILE D 1 101 ? 187.617 126.387 114.015 1.00 127.43 ? 94  ILE B N   1 
ATOM   5764  C  CA  . ILE D 1 101 ? 187.631 127.669 113.324 1.00 127.43 ? 94  ILE B CA  1 
ATOM   5765  C  C   . ILE D 1 101 ? 189.080 128.036 113.041 1.00 127.43 ? 94  ILE B C   1 
ATOM   5766  O  O   . ILE D 1 101 ? 189.903 128.089 113.962 1.00 127.43 ? 94  ILE B O   1 
ATOM   5767  C  CB  . ILE D 1 101 ? 186.942 128.771 114.149 1.00 127.43 ? 94  ILE B CB  1 
ATOM   5768  C  CG1 . ILE D 1 101 ? 185.562 128.310 114.620 1.00 127.43 ? 94  ILE B CG1 1 
ATOM   5769  C  CG2 . ILE D 1 101 ? 186.838 130.053 113.339 1.00 127.43 ? 94  ILE B CG2 1 
ATOM   5770  C  CD1 . ILE D 1 101 ? 185.513 127.938 116.085 1.00 127.43 ? 94  ILE B CD1 1 
ATOM   5771  N  N   . SER D 1 102 ? 189.387 128.288 111.774 1.00 136.73 ? 95  SER B N   1 
ATOM   5772  C  CA  . SER D 1 102 ? 190.725 128.678 111.346 1.00 136.73 ? 95  SER B CA  1 
ATOM   5773  C  C   . SER D 1 102 ? 190.707 130.168 111.030 1.00 136.73 ? 95  SER B C   1 
ATOM   5774  O  O   . SER D 1 102 ? 190.065 130.596 110.065 1.00 136.73 ? 95  SER B O   1 
ATOM   5775  C  CB  . SER D 1 102 ? 191.172 127.864 110.134 1.00 136.73 ? 95  SER B CB  1 
ATOM   5776  O  OG  . SER D 1 102 ? 190.388 128.174 108.995 1.00 136.73 ? 95  SER B OG  1 
ATOM   5777  N  N   . TYR D 1 103 ? 191.397 130.952 111.852 1.00 137.66 ? 96  TYR B N   1 
ATOM   5778  C  CA  . TYR D 1 103 ? 191.541 132.383 111.642 1.00 137.66 ? 96  TYR B CA  1 
ATOM   5779  C  C   . TYR D 1 103 ? 192.747 132.645 110.751 1.00 137.66 ? 96  TYR B C   1 
ATOM   5780  O  O   . TYR D 1 103 ? 193.858 132.185 111.045 1.00 137.66 ? 96  TYR B O   1 
ATOM   5781  C  CB  . TYR D 1 103 ? 191.706 133.106 112.978 1.00 137.66 ? 96  TYR B CB  1 
ATOM   5782  C  CG  . TYR D 1 103 ? 190.482 133.075 113.862 1.00 137.66 ? 96  TYR B CG  1 
ATOM   5783  C  CD1 . TYR D 1 103 ? 189.298 133.680 113.465 1.00 137.66 ? 96  TYR B CD1 1 
ATOM   5784  C  CD2 . TYR D 1 103 ? 190.516 132.449 115.100 1.00 137.66 ? 96  TYR B CD2 1 
ATOM   5785  C  CE1 . TYR D 1 103 ? 188.180 133.657 114.276 1.00 137.66 ? 96  TYR B CE1 1 
ATOM   5786  C  CE2 . TYR D 1 103 ? 189.406 132.422 115.916 1.00 137.66 ? 96  TYR B CE2 1 
ATOM   5787  C  CZ  . TYR D 1 103 ? 188.240 133.027 115.500 1.00 137.66 ? 96  TYR B CZ  1 
ATOM   5788  O  OH  . TYR D 1 103 ? 187.133 132.997 116.315 1.00 137.66 ? 96  TYR B OH  1 
ATOM   5789  N  N   . TYR D 1 104 ? 192.524 133.391 109.670 1.00 144.78 ? 97  TYR B N   1 
ATOM   5790  C  CA  . TYR D 1 104 ? 193.542 133.694 108.673 1.00 144.78 ? 97  TYR B CA  1 
ATOM   5791  C  C   . TYR D 1 104 ? 193.938 135.158 108.797 1.00 144.78 ? 97  TYR B C   1 
ATOM   5792  O  O   . TYR D 1 104 ? 193.082 136.045 108.713 1.00 144.78 ? 97  TYR B O   1 
ATOM   5793  C  CB  . TYR D 1 104 ? 193.028 133.405 107.262 1.00 144.78 ? 97  TYR B CB  1 
ATOM   5794  C  CG  . TYR D 1 104 ? 192.662 131.961 107.017 1.00 144.78 ? 97  TYR B CG  1 
ATOM   5795  C  CD1 . TYR D 1 104 ? 193.583 130.945 107.226 1.00 144.78 ? 97  TYR B CD1 1 
ATOM   5796  C  CD2 . TYR D 1 104 ? 191.394 131.614 106.570 1.00 144.78 ? 97  TYR B CD2 1 
ATOM   5797  C  CE1 . TYR D 1 104 ? 193.252 129.623 107.000 1.00 144.78 ? 97  TYR B CE1 1 
ATOM   5798  C  CE2 . TYR D 1 104 ? 191.053 130.296 106.342 1.00 144.78 ? 97  TYR B CE2 1 
ATOM   5799  C  CZ  . TYR D 1 104 ? 191.986 129.304 106.559 1.00 144.78 ? 97  TYR B CZ  1 
ATOM   5800  O  OH  . TYR D 1 104 ? 191.650 127.989 106.333 1.00 144.78 ? 97  TYR B OH  1 
ATOM   5801  N  N   . GLY D 1 105 ? 195.231 135.409 108.983 1.00 154.15 ? 98  GLY B N   1 
ATOM   5802  C  CA  . GLY D 1 105 ? 195.738 136.756 109.077 1.00 154.15 ? 98  GLY B CA  1 
ATOM   5803  C  C   . GLY D 1 105 ? 196.853 137.017 108.088 1.00 154.15 ? 98  GLY B C   1 
ATOM   5804  O  O   . GLY D 1 105 ? 197.553 136.098 107.650 1.00 154.15 ? 98  GLY B O   1 
ATOM   5805  N  N   . PRO D 1 106 ? 197.031 138.283 107.702 1.00 158.00 ? 99  PRO B N   1 
ATOM   5806  C  CA  . PRO D 1 106 ? 198.142 138.620 106.796 1.00 158.00 ? 99  PRO B CA  1 
ATOM   5807  C  C   . PRO D 1 106 ? 199.504 138.267 107.363 1.00 158.00 ? 99  PRO B C   1 
ATOM   5808  O  O   . PRO D 1 106 ? 200.412 137.911 106.602 1.00 158.00 ? 99  PRO B O   1 
ATOM   5809  C  CB  . PRO D 1 106 ? 197.987 140.135 106.594 1.00 158.00 ? 99  PRO B CB  1 
ATOM   5810  C  CG  . PRO D 1 106 ? 197.157 140.600 107.750 1.00 158.00 ? 99  PRO B CG  1 
ATOM   5811  C  CD  . PRO D 1 106 ? 196.241 139.466 108.081 1.00 158.00 ? 99  PRO B CD  1 
ATOM   5812  N  N   . LYS D 1 107 ? 199.672 138.356 108.678 1.00 160.42 ? 100 LYS B N   1 
ATOM   5813  C  CA  . LYS D 1 107 ? 200.905 137.980 109.350 1.00 160.42 ? 100 LYS B CA  1 
ATOM   5814  C  C   . LYS D 1 107 ? 200.646 136.791 110.267 1.00 160.42 ? 100 LYS B C   1 
ATOM   5815  O  O   . LYS D 1 107 ? 199.525 136.589 110.744 1.00 160.42 ? 100 LYS B O   1 
ATOM   5816  C  CB  . LYS D 1 107 ? 201.472 139.151 110.158 1.00 160.42 ? 100 LYS B CB  1 
ATOM   5817  C  CG  . LYS D 1 107 ? 201.817 140.373 109.323 1.00 160.42 ? 100 LYS B CG  1 
ATOM   5818  C  CD  . LYS D 1 107 ? 202.274 141.529 110.197 1.00 160.42 ? 100 LYS B CD  1 
ATOM   5819  C  CE  . LYS D 1 107 ? 202.625 142.750 109.362 1.00 160.42 ? 100 LYS B CE  1 
ATOM   5820  N  NZ  . LYS D 1 107 ? 203.057 143.897 110.207 1.00 160.42 ? 100 LYS B NZ  1 
ATOM   5821  N  N   . THR D 1 108 ? 201.702 135.998 110.497 1.00 159.36 ? 101 THR B N   1 
ATOM   5822  C  CA  . THR D 1 108 ? 201.711 134.810 111.351 1.00 159.36 ? 101 THR B CA  1 
ATOM   5823  C  C   . THR D 1 108 ? 200.835 133.702 110.769 1.00 159.36 ? 101 THR B C   1 
ATOM   5824  O  O   . THR D 1 108 ? 199.921 133.976 109.982 1.00 159.36 ? 101 THR B O   1 
ATOM   5825  C  CB  . THR D 1 108 ? 201.265 135.151 112.780 1.00 159.36 ? 101 THR B CB  1 
ATOM   5826  O  OG1 . THR D 1 108 ? 199.861 135.440 112.796 1.00 159.36 ? 101 THR B OG1 1 
ATOM   5827  C  CG2 . THR D 1 108 ? 202.042 136.346 113.320 1.00 159.36 ? 101 THR B CG2 1 
ATOM   5828  N  N   . PRO D 1 109 ? 201.092 132.443 111.116 1.00 157.22 ? 102 PRO B N   1 
ATOM   5829  C  CA  . PRO D 1 109 ? 200.277 131.339 110.587 1.00 157.22 ? 102 PRO B CA  1 
ATOM   5830  C  C   . PRO D 1 109 ? 198.855 131.402 111.113 1.00 157.22 ? 102 PRO B C   1 
ATOM   5831  O  O   . PRO D 1 109 ? 198.590 132.045 112.141 1.00 157.22 ? 102 PRO B O   1 
ATOM   5832  C  CB  . PRO D 1 109 ? 201.006 130.085 111.095 1.00 157.22 ? 102 PRO B CB  1 
ATOM   5833  C  CG  . PRO D 1 109 ? 202.395 130.540 111.387 1.00 157.22 ? 102 PRO B CG  1 
ATOM   5834  C  CD  . PRO D 1 109 ? 202.261 131.950 111.864 1.00 157.22 ? 102 PRO B CD  1 
ATOM   5835  N  N   . PRO D 1 110 ? 197.908 130.757 110.428 1.00 148.90 ? 103 PRO B N   1 
ATOM   5836  C  CA  . PRO D 1 110 ? 196.516 130.771 110.893 1.00 148.90 ? 103 PRO B CA  1 
ATOM   5837  C  C   . PRO D 1 110 ? 196.378 130.139 112.270 1.00 148.90 ? 103 PRO B C   1 
ATOM   5838  O  O   . PRO D 1 110 ? 197.127 129.233 112.641 1.00 148.90 ? 103 PRO B O   1 
ATOM   5839  C  CB  . PRO D 1 110 ? 195.777 129.950 109.829 1.00 148.90 ? 103 PRO B CB  1 
ATOM   5840  C  CG  . PRO D 1 110 ? 196.657 130.012 108.622 1.00 148.90 ? 103 PRO B CG  1 
ATOM   5841  C  CD  . PRO D 1 110 ? 198.055 130.040 109.151 1.00 148.90 ? 103 PRO B CD  1 
ATOM   5842  N  N   . VAL D 1 111 ? 195.403 130.629 113.032 1.00 137.95 ? 104 VAL B N   1 
ATOM   5843  C  CA  . VAL D 1 111 ? 195.196 130.215 114.418 1.00 137.95 ? 104 VAL B CA  1 
ATOM   5844  C  C   . VAL D 1 111 ? 193.940 129.358 114.489 1.00 137.95 ? 104 VAL B C   1 
ATOM   5845  O  O   . VAL D 1 111 ? 192.899 129.725 113.937 1.00 137.95 ? 104 VAL B O   1 
ATOM   5846  C  CB  . VAL D 1 111 ? 195.090 131.427 115.358 1.00 137.95 ? 104 VAL B CB  1 
ATOM   5847  C  CG1 . VAL D 1 111 ? 195.104 130.974 116.809 1.00 137.95 ? 104 VAL B CG1 1 
ATOM   5848  C  CG2 . VAL D 1 111 ? 196.223 132.405 115.090 1.00 137.95 ? 104 VAL B CG2 1 
ATOM   5849  N  N   . LYS D 1 112 ? 194.032 128.224 115.177 1.00 131.05 ? 105 LYS B N   1 
ATOM   5850  C  CA  . LYS D 1 112 ? 192.938 127.265 115.252 1.00 131.05 ? 105 LYS B CA  1 
ATOM   5851  C  C   . LYS D 1 112 ? 192.253 127.356 116.609 1.00 131.05 ? 105 LYS B C   1 
ATOM   5852  O  O   . LYS D 1 112 ? 192.918 127.344 117.649 1.00 131.05 ? 105 LYS B O   1 
ATOM   5853  C  CB  . LYS D 1 112 ? 193.443 125.841 115.010 1.00 131.05 ? 105 LYS B CB  1 
ATOM   5854  C  CG  . LYS D 1 112 ? 193.903 125.588 113.585 1.00 131.05 ? 105 LYS B CG  1 
ATOM   5855  C  CD  . LYS D 1 112 ? 194.288 124.134 113.375 1.00 131.05 ? 105 LYS B CD  1 
ATOM   5856  C  CE  . LYS D 1 112 ? 194.677 123.872 111.929 1.00 131.05 ? 105 LYS B CE  1 
ATOM   5857  N  NZ  . LYS D 1 112 ? 194.976 122.434 111.685 1.00 131.05 ? 105 LYS B NZ  1 
ATOM   5858  N  N   . ALA D 1 113 ? 190.925 127.447 116.589 1.00 119.83 ? 106 ALA B N   1 
ATOM   5859  C  CA  . ALA D 1 113 ? 190.104 127.444 117.789 1.00 119.83 ? 106 ALA B CA  1 
ATOM   5860  C  C   . ALA D 1 113 ? 189.146 126.263 117.741 1.00 119.83 ? 106 ALA B C   1 
ATOM   5861  O  O   . ALA D 1 113 ? 188.658 125.884 116.672 1.00 119.83 ? 106 ALA B O   1 
ATOM   5862  C  CB  . ALA D 1 113 ? 189.319 128.753 117.933 1.00 119.83 ? 106 ALA B CB  1 
ATOM   5863  N  N   . LEU D 1 114 ? 188.870 125.687 118.910 1.00 106.05 ? 107 LEU B N   1 
ATOM   5864  C  CA  . LEU D 1 114 ? 188.107 124.452 119.014 1.00 106.05 ? 107 LEU B CA  1 
ATOM   5865  C  C   . LEU D 1 114 ? 186.880 124.659 119.888 1.00 106.05 ? 107 LEU B C   1 
ATOM   5866  O  O   . LEU D 1 114 ? 186.891 125.462 120.826 1.00 106.05 ? 107 LEU B O   1 
ATOM   5867  C  CB  . LEU D 1 114 ? 188.963 123.319 119.596 1.00 106.05 ? 107 LEU B CB  1 
ATOM   5868  C  CG  . LEU D 1 114 ? 189.733 122.439 118.610 1.00 106.05 ? 107 LEU B CG  1 
ATOM   5869  C  CD1 . LEU D 1 114 ? 190.000 121.073 119.218 1.00 106.05 ? 107 LEU B CD1 1 
ATOM   5870  C  CD2 . LEU D 1 114 ? 188.975 122.305 117.301 1.00 106.05 ? 107 LEU B CD2 1 
ATOM   5871  N  N   . LEU D 1 115 ? 185.815 123.922 119.572 1.00 97.30  ? 108 LEU B N   1 
ATOM   5872  C  CA  . LEU D 1 115 ? 184.603 123.930 120.379 1.00 97.30  ? 108 LEU B CA  1 
ATOM   5873  C  C   . LEU D 1 115 ? 184.018 122.527 120.416 1.00 97.30  ? 108 LEU B C   1 
ATOM   5874  O  O   . LEU D 1 115 ? 183.796 121.919 119.365 1.00 97.30  ? 108 LEU B O   1 
ATOM   5875  C  CB  . LEU D 1 115 ? 183.572 124.917 119.824 1.00 97.30  ? 108 LEU B CB  1 
ATOM   5876  C  CG  . LEU D 1 115 ? 182.231 124.945 120.557 1.00 97.30  ? 108 LEU B CG  1 
ATOM   5877  C  CD1 . LEU D 1 115 ? 182.405 125.480 121.967 1.00 97.30  ? 108 LEU B CD1 1 
ATOM   5878  C  CD2 . LEU D 1 115 ? 181.215 125.770 119.789 1.00 97.30  ? 108 LEU B CD2 1 
ATOM   5879  N  N   . TYR D 1 116 ? 183.765 122.019 121.620 1.00 94.63  ? 109 TYR B N   1 
ATOM   5880  C  CA  . TYR D 1 116 ? 183.218 120.683 121.820 1.00 94.63  ? 109 TYR B CA  1 
ATOM   5881  C  C   . TYR D 1 116 ? 181.749 120.781 122.206 1.00 94.63  ? 109 TYR B C   1 
ATOM   5882  O  O   . TYR D 1 116 ? 181.383 121.569 123.084 1.00 94.63  ? 109 TYR B O   1 
ATOM   5883  C  CB  . TYR D 1 116 ? 183.999 119.923 122.892 1.00 94.63  ? 109 TYR B CB  1 
ATOM   5884  C  CG  . TYR D 1 116 ? 185.336 119.406 122.416 1.00 94.63  ? 109 TYR B CG  1 
ATOM   5885  C  CD1 . TYR D 1 116 ? 185.441 118.684 121.236 1.00 94.63  ? 109 TYR B CD1 1 
ATOM   5886  C  CD2 . TYR D 1 116 ? 186.492 119.633 123.149 1.00 94.63  ? 109 TYR B CD2 1 
ATOM   5887  C  CE1 . TYR D 1 116 ? 186.658 118.207 120.795 1.00 94.63  ? 109 TYR B CE1 1 
ATOM   5888  C  CE2 . TYR D 1 116 ? 187.715 119.158 122.717 1.00 94.63  ? 109 TYR B CE2 1 
ATOM   5889  C  CZ  . TYR D 1 116 ? 187.792 118.446 121.539 1.00 94.63  ? 109 TYR B CZ  1 
ATOM   5890  O  OH  . TYR D 1 116 ? 189.007 117.971 121.104 1.00 94.63  ? 109 TYR B OH  1 
ATOM   5891  N  N   . LEU D 1 117 ? 180.918 119.974 121.556 1.00 92.96  ? 110 LEU B N   1 
ATOM   5892  C  CA  . LEU D 1 117 ? 179.473 120.037 121.698 1.00 92.96  ? 110 LEU B CA  1 
ATOM   5893  C  C   . LEU D 1 117 ? 178.917 118.709 122.187 1.00 92.96  ? 110 LEU B C   1 
ATOM   5894  O  O   . LEU D 1 117 ? 179.256 117.639 121.654 1.00 92.96  ? 110 LEU B O   1 
ATOM   5895  C  CB  . LEU D 1 117 ? 178.794 120.407 120.375 1.00 92.96  ? 110 LEU B CB  1 
ATOM   5896  C  CG  . LEU D 1 117 ? 178.800 121.878 119.964 1.00 92.96  ? 110 LEU B CG  1 
ATOM   5897  C  CD1 . LEU D 1 117 ? 178.484 122.766 121.155 1.00 92.96  ? 110 LEU B CD1 1 
ATOM   5898  C  CD2 . LEU D 1 117 ? 180.124 122.262 119.332 1.00 92.96  ? 110 LEU B CD2 1 
ATOM   5899  N  N   . THR D 1 118 ? 178.067 118.803 123.211 1.00 85.85  ? 111 THR B N   1 
ATOM   5900  C  CA  . THR D 1 118 ? 177.203 117.727 123.686 1.00 85.85  ? 111 THR B CA  1 
ATOM   5901  C  C   . THR D 1 118 ? 175.772 118.245 123.659 1.00 85.85  ? 111 THR B C   1 
ATOM   5902  O  O   . THR D 1 118 ? 175.495 119.323 124.195 1.00 85.85  ? 111 THR B O   1 
ATOM   5903  C  CB  . THR D 1 118 ? 177.581 117.295 125.104 1.00 85.85  ? 111 THR B CB  1 
ATOM   5904  O  OG1 . THR D 1 118 ? 176.860 116.109 125.457 1.00 85.85  ? 111 THR B OG1 1 
ATOM   5905  C  CG2 . THR D 1 118 ? 177.267 118.395 126.104 1.00 85.85  ? 111 THR B CG2 1 
ATOM   5906  N  N   . ALA D 1 119 ? 174.870 117.488 123.045 1.00 76.64  ? 112 ALA B N   1 
ATOM   5907  C  CA  . ALA D 1 119 ? 173.482 117.904 122.905 1.00 76.64  ? 112 ALA B CA  1 
ATOM   5908  C  C   . ALA D 1 119 ? 172.568 117.004 123.721 1.00 76.64  ? 112 ALA B C   1 
ATOM   5909  O  O   . ALA D 1 119 ? 172.692 115.777 123.686 1.00 76.64  ? 112 ALA B O   1 
ATOM   5910  C  CB  . ALA D 1 119 ? 173.035 117.886 121.445 1.00 76.64  ? 112 ALA B CB  1 
ATOM   5911  N  N   . VAL D 1 120 ? 171.640 117.626 124.439 1.00 65.09  ? 113 VAL B N   1 
ATOM   5912  C  CA  . VAL D 1 120 ? 170.653 116.899 125.224 1.00 65.09  ? 113 VAL B CA  1 
ATOM   5913  C  C   . VAL D 1 120 ? 169.276 117.189 124.651 1.00 65.09  ? 113 VAL B C   1 
ATOM   5914  O  O   . VAL D 1 120 ? 169.135 117.996 123.726 1.00 65.09  ? 113 VAL B O   1 
ATOM   5915  C  CB  . VAL D 1 120 ? 170.733 117.287 126.711 1.00 65.09  ? 113 VAL B CB  1 
ATOM   5916  C  CG1 . VAL D 1 120 ? 172.180 117.367 127.153 1.00 65.09  ? 113 VAL B CG1 1 
ATOM   5917  C  CG2 . VAL D 1 120 ? 170.037 118.616 126.948 1.00 65.09  ? 113 VAL B CG2 1 
ATOM   5918  N  N   . GLU D 1 121 ? 168.252 116.529 125.183 1.00 58.64  ? 114 GLU B N   1 
ATOM   5919  C  CA  . GLU D 1 121 ? 166.871 116.808 124.812 1.00 58.64  ? 114 GLU B CA  1 
ATOM   5920  C  C   . GLU D 1 121 ? 166.040 116.902 126.080 1.00 58.64  ? 114 GLU B C   1 
ATOM   5921  O  O   . GLU D 1 121 ? 165.847 115.898 126.771 1.00 58.64  ? 114 GLU B O   1 
ATOM   5922  C  CB  . GLU D 1 121 ? 166.316 115.727 123.881 1.00 58.64  ? 114 GLU B CB  1 
ATOM   5923  C  CG  . GLU D 1 121 ? 164.813 115.797 123.679 1.00 58.64  ? 114 GLU B CG  1 
ATOM   5924  C  CD  . GLU D 1 121 ? 164.330 114.854 122.596 1.00 58.64  ? 114 GLU B CD  1 
ATOM   5925  O  OE1 . GLU D 1 121 ? 164.915 114.866 121.492 1.00 58.64  ? 114 GLU B OE1 1 
ATOM   5926  O  OE2 . GLU D 1 121 ? 163.368 114.100 122.849 1.00 58.64  ? 114 GLU B OE2 1 
ATOM   5927  N  N   . ILE D 1 122 ? 165.559 118.103 126.383 1.00 47.50  ? 115 ILE B N   1 
ATOM   5928  C  CA  . ILE D 1 122 ? 164.717 118.355 127.547 1.00 47.50  ? 115 ILE B CA  1 
ATOM   5929  C  C   . ILE D 1 122 ? 163.414 118.951 127.042 1.00 47.50  ? 115 ILE B C   1 
ATOM   5930  O  O   . ILE D 1 122 ? 163.411 120.055 126.485 1.00 47.50  ? 115 ILE B O   1 
ATOM   5931  C  CB  . ILE D 1 122 ? 165.391 119.304 128.550 1.00 47.50  ? 115 ILE B CB  1 
ATOM   5932  C  CG1 . ILE D 1 122 ? 166.625 118.643 129.166 1.00 47.50  ? 115 ILE B CG1 1 
ATOM   5933  C  CG2 . ILE D 1 122 ? 164.397 119.745 129.614 1.00 47.50  ? 115 ILE B CG2 1 
ATOM   5934  C  CD1 . ILE D 1 122 ? 166.369 117.958 130.488 1.00 47.50  ? 115 ILE B CD1 1 
ATOM   5935  N  N   . SER D 1 123 ? 162.310 118.234 127.230 1.00 46.12  ? 116 SER B N   1 
ATOM   5936  C  CA  . SER D 1 123 ? 161.032 118.675 126.682 1.00 46.12  ? 116 SER B CA  1 
ATOM   5937  C  C   . SER D 1 123 ? 159.946 118.535 127.733 1.00 46.12  ? 116 SER B C   1 
ATOM   5938  O  O   . SER D 1 123 ? 159.610 117.418 128.132 1.00 46.12  ? 116 SER B O   1 
ATOM   5939  C  CB  . SER D 1 123 ? 160.668 117.874 125.429 1.00 46.12  ? 116 SER B CB  1 
ATOM   5940  O  OG  . SER D 1 123 ? 161.744 117.855 124.508 1.00 46.12  ? 116 SER B OG  1 
ATOM   5941  N  N   . LEU D 1 124 ? 159.398 119.662 128.175 1.00 39.08  ? 117 LEU B N   1 
ATOM   5942  C  CA  . LEU D 1 124 ? 158.238 119.672 129.056 1.00 39.08  ? 117 LEU B CA  1 
ATOM   5943  C  C   . LEU D 1 124 ? 157.006 119.936 128.203 1.00 39.08  ? 117 LEU B C   1 
ATOM   5944  O  O   . LEU D 1 124 ? 156.898 120.994 127.575 1.00 39.08  ? 117 LEU B O   1 
ATOM   5945  C  CB  . LEU D 1 124 ? 158.385 120.728 130.152 1.00 39.08  ? 117 LEU B CB  1 
ATOM   5946  C  CG  . LEU D 1 124 ? 157.359 120.682 131.286 1.00 39.08  ? 117 LEU B CG  1 
ATOM   5947  C  CD1 . LEU D 1 124 ? 158.025 120.912 132.630 1.00 39.08  ? 117 LEU B CD1 1 
ATOM   5948  C  CD2 . LEU D 1 124 ? 156.263 121.706 131.061 1.00 39.08  ? 117 LEU B CD2 1 
ATOM   5949  N  N   . CYS D 1 125 ? 156.085 118.979 128.182 1.00 46.60  ? 118 CYS B N   1 
ATOM   5950  C  CA  . CYS D 1 125 ? 154.933 119.034 127.297 1.00 46.60  ? 118 CYS B CA  1 
ATOM   5951  C  C   . CYS D 1 125 ? 153.653 118.820 128.089 1.00 46.60  ? 118 CYS B C   1 
ATOM   5952  O  O   . CYS D 1 125 ? 153.634 118.113 129.099 1.00 46.60  ? 118 CYS B O   1 
ATOM   5953  C  CB  . CYS D 1 125 ? 155.035 117.983 126.185 1.00 46.60  ? 118 CYS B CB  1 
ATOM   5954  S  SG  . CYS D 1 125 ? 153.487 117.667 125.314 1.00 46.60  ? 118 CYS B SG  1 
ATOM   5955  N  N   . ALA D 1 126 ? 152.581 119.446 127.615 1.00 45.50  ? 119 ALA B N   1 
ATOM   5956  C  CA  . ALA D 1 126 ? 151.257 119.292 128.198 1.00 45.50  ? 119 ALA B CA  1 
ATOM   5957  C  C   . ALA D 1 126 ? 150.254 119.231 127.054 1.00 45.50  ? 119 ALA B C   1 
ATOM   5958  O  O   . ALA D 1 126 ? 150.622 119.068 125.887 1.00 45.50  ? 119 ALA B O   1 
ATOM   5959  C  CB  . ALA D 1 126 ? 150.953 120.427 129.182 1.00 45.50  ? 119 ALA B CB  1 
ATOM   5960  N  N   . ASP D 1 127 ? 148.973 119.363 127.383 1.00 46.61  ? 120 ASP B N   1 
ATOM   5961  C  CA  . ASP D 1 127 ? 147.917 119.328 126.372 1.00 46.61  ? 120 ASP B CA  1 
ATOM   5962  C  C   . ASP D 1 127 ? 147.718 120.732 125.799 1.00 46.61  ? 120 ASP B C   1 
ATOM   5963  O  O   . ASP D 1 127 ? 146.671 121.363 125.941 1.00 46.61  ? 120 ASP B O   1 
ATOM   5964  C  CB  . ASP D 1 127 ? 146.631 118.772 126.966 1.00 46.61  ? 120 ASP B CB  1 
ATOM   5965  C  CG  . ASP D 1 127 ? 145.685 118.246 125.912 1.00 46.61  ? 120 ASP B CG  1 
ATOM   5966  O  OD1 . ASP D 1 127 ? 146.101 118.139 124.740 1.00 46.61  ? 120 ASP B OD1 1 
ATOM   5967  O  OD2 . ASP D 1 127 ? 144.526 117.941 126.255 1.00 46.61  ? 120 ASP B OD2 1 
ATOM   5968  N  N   . ILE D 1 128 ? 148.768 121.216 125.132 1.00 42.16  ? 121 ILE B N   1 
ATOM   5969  C  CA  . ILE D 1 128 ? 148.748 122.572 124.591 1.00 42.16  ? 121 ILE B CA  1 
ATOM   5970  C  C   . ILE D 1 128 ? 147.786 122.723 123.421 1.00 42.16  ? 121 ILE B C   1 
ATOM   5971  O  O   . ILE D 1 128 ? 147.216 123.804 123.240 1.00 42.16  ? 121 ILE B O   1 
ATOM   5972  C  CB  . ILE D 1 128 ? 150.154 123.015 124.159 1.00 42.16  ? 121 ILE B CB  1 
ATOM   5973  C  CG1 . ILE D 1 128 ? 150.848 121.902 123.375 1.00 42.16  ? 121 ILE B CG1 1 
ATOM   5974  C  CG2 . ILE D 1 128 ? 150.979 123.416 125.369 1.00 42.16  ? 121 ILE B CG2 1 
ATOM   5975  C  CD1 . ILE D 1 128 ? 152.276 122.225 123.002 1.00 42.16  ? 121 ILE B CD1 1 
ATOM   5976  N  N   . THR D 1 129 ? 147.586 121.677 122.624 1.00 44.45  ? 122 THR B N   1 
ATOM   5977  C  CA  . THR D 1 129 ? 146.718 121.765 121.456 1.00 44.45  ? 122 THR B CA  1 
ATOM   5978  C  C   . THR D 1 129 ? 145.242 121.635 121.802 1.00 44.45  ? 122 THR B C   1 
ATOM   5979  O  O   . THR D 1 129 ? 144.406 121.719 120.896 1.00 44.45  ? 122 THR B O   1 
ATOM   5980  C  CB  . THR D 1 129 ? 147.094 120.690 120.432 1.00 44.45  ? 122 THR B CB  1 
ATOM   5981  O  OG1 . THR D 1 129 ? 146.955 119.394 121.024 1.00 44.45  ? 122 THR B OG1 1 
ATOM   5982  C  CG2 . THR D 1 129 ? 148.526 120.878 119.965 1.00 44.45  ? 122 THR B CG2 1 
ATOM   5983  N  N   . ARG D 1 130 ? 144.922 121.441 123.087 1.00 41.11  ? 123 ARG B N   1 
ATOM   5984  C  CA  . ARG D 1 130 ? 143.506 121.301 123.535 1.00 41.11  ? 123 ARG B CA  1 
ATOM   5985  C  C   . ARG D 1 130 ? 142.845 120.128 122.789 1.00 41.11  ? 123 ARG B C   1 
ATOM   5986  O  O   . ARG D 1 130 ? 141.669 120.274 122.391 1.00 41.11  ? 123 ARG B O   1 
ATOM   5987  C  CB  . ARG D 1 130 ? 142.740 122.622 123.365 1.00 41.11  ? 123 ARG B CB  1 
ATOM   5988  C  CG  . ARG D 1 130 ? 143.347 123.800 124.115 1.00 41.11  ? 123 ARG B CG  1 
ATOM   5989  C  CD  . ARG D 1 130 ? 143.642 124.999 123.223 1.00 41.11  ? 123 ARG B CD  1 
ATOM   5990  N  NE  . ARG D 1 130 ? 144.137 126.158 123.975 1.00 41.11  ? 123 ARG B NE  1 
ATOM   5991  C  CZ  . ARG D 1 130 ? 143.831 127.424 123.710 1.00 41.11  ? 123 ARG B CZ  1 
ATOM   5992  N  NH1 . ARG D 1 130 ? 144.541 128.404 124.240 1.00 41.11  ? 123 ARG B NH1 1 
ATOM   5993  N  NH2 . ARG D 1 130 ? 142.815 127.706 122.914 1.00 41.11  ? 123 ARG B NH2 1 
ATOM   5994  N  N   . THR D 1 131 ? 143.563 119.015 122.613 1.00 48.47  ? 124 THR B N   1 
ATOM   5995  C  CA  . THR D 1 131 ? 143.047 117.825 121.948 1.00 48.47  ? 124 THR B CA  1 
ATOM   5996  C  C   . THR D 1 131 ? 142.794 116.670 122.901 1.00 48.47  ? 124 THR B C   1 
ATOM   5997  O  O   . THR D 1 131 ? 141.712 116.079 122.874 1.00 48.47  ? 124 THR B O   1 
ATOM   5998  C  CB  . THR D 1 131 ? 144.019 117.370 120.852 1.00 48.47  ? 124 THR B CB  1 
ATOM   5999  O  OG1 . THR D 1 131 ? 143.929 118.261 119.733 1.00 48.47  ? 124 THR B OG1 1 
ATOM   6000  C  CG2 . THR D 1 131 ? 143.688 115.957 120.391 1.00 48.47  ? 124 THR B CG2 1 
ATOM   6001  N  N   . GLY D 1 132 ? 143.759 116.341 123.754 1.00 55.19  ? 125 GLY B N   1 
ATOM   6002  C  CA  . GLY D 1 132 ? 143.598 115.255 124.698 1.00 55.19  ? 125 GLY B CA  1 
ATOM   6003  C  C   . GLY D 1 132 ? 144.777 114.306 124.708 1.00 55.19  ? 125 GLY B C   1 
ATOM   6004  O  O   . GLY D 1 132 ? 144.726 113.246 125.340 1.00 55.19  ? 125 GLY B O   1 
ATOM   6005  N  N   . LYS D 1 133 ? 145.848 114.678 124.012 1.00 63.96  ? 126 LYS B N   1 
ATOM   6006  C  CA  . LYS D 1 133 ? 147.042 113.853 123.904 1.00 63.96  ? 126 LYS B CA  1 
ATOM   6007  C  C   . LYS D 1 133 ? 148.265 114.675 124.278 1.00 63.96  ? 126 LYS B C   1 
ATOM   6008  O  O   . LYS D 1 133 ? 148.360 115.856 123.932 1.00 63.96  ? 126 LYS B O   1 
ATOM   6009  C  CB  . LYS D 1 133 ? 147.207 113.291 122.486 1.00 63.96  ? 126 LYS B CB  1 
ATOM   6010  C  CG  . LYS D 1 133 ? 145.988 112.551 121.964 1.00 63.96  ? 126 LYS B CG  1 
ATOM   6011  C  CD  . LYS D 1 133 ? 146.212 112.043 120.550 1.00 63.96  ? 126 LYS B CD  1 
ATOM   6012  C  CE  . LYS D 1 133 ? 144.986 111.315 120.025 1.00 63.96  ? 126 LYS B CE  1 
ATOM   6013  N  NZ  . LYS D 1 133 ? 145.214 110.753 118.666 1.00 63.96  ? 126 LYS B NZ  1 
ATOM   6014  N  N   . VAL D 1 134 ? 149.198 114.045 124.986 1.00 57.11  ? 127 VAL B N   1 
ATOM   6015  C  CA  . VAL D 1 134 ? 150.423 114.715 125.400 1.00 57.11  ? 127 VAL B CA  1 
ATOM   6016  C  C   . VAL D 1 134 ? 151.616 114.149 124.640 1.00 57.11  ? 127 VAL B C   1 
ATOM   6017  O  O   . VAL D 1 134 ? 151.573 114.002 123.419 1.00 57.11  ? 127 VAL B O   1 
ATOM   6018  C  CB  . VAL D 1 134 ? 150.638 114.594 126.915 1.00 57.11  ? 127 VAL B CB  1 
ATOM   6019  C  CG1 . VAL D 1 134 ? 149.358 114.926 127.660 1.00 57.11  ? 127 VAL B CG1 1 
ATOM   6020  C  CG2 . VAL D 1 134 ? 151.117 113.198 127.268 1.00 57.11  ? 127 VAL B CG2 1 
ATOM   6021  N  N   . GLN D 1 143 ? 154.377 130.858 121.228 1.00 58.59  ? 136 GLN B N   1 
ATOM   6022  C  CA  . GLN D 1 143 ? 154.671 129.725 122.096 1.00 58.59  ? 136 GLN B CA  1 
ATOM   6023  C  C   . GLN D 1 143 ? 154.856 130.188 123.537 1.00 58.59  ? 136 GLN B C   1 
ATOM   6024  O  O   . GLN D 1 143 ? 155.188 131.348 123.784 1.00 58.59  ? 136 GLN B O   1 
ATOM   6025  C  CB  . GLN D 1 143 ? 155.921 128.987 121.609 1.00 58.59  ? 136 GLN B CB  1 
ATOM   6026  C  CG  . GLN D 1 143 ? 155.733 128.242 120.296 1.00 58.59  ? 136 GLN B CG  1 
ATOM   6027  C  CD  . GLN D 1 143 ? 155.036 126.906 120.468 1.00 58.59  ? 136 GLN B CD  1 
ATOM   6028  O  OE1 . GLN D 1 143 ? 153.893 126.840 120.920 1.00 58.59  ? 136 GLN B OE1 1 
ATOM   6029  N  NE2 . GLN D 1 143 ? 155.724 125.830 120.103 1.00 58.59  ? 136 GLN B NE2 1 
ATOM   6030  N  N   . ARG D 1 144 ? 154.638 129.271 124.483 1.00 52.58  ? 137 ARG B N   1 
ATOM   6031  C  CA  . ARG D 1 144 ? 154.733 129.559 125.915 1.00 52.58  ? 137 ARG B CA  1 
ATOM   6032  C  C   . ARG D 1 144 ? 153.820 130.713 126.324 1.00 52.58  ? 137 ARG B C   1 
ATOM   6033  O  O   . ARG D 1 144 ? 154.165 131.513 127.197 1.00 52.58  ? 137 ARG B O   1 
ATOM   6034  C  CB  . ARG D 1 144 ? 156.178 129.847 126.334 1.00 52.58  ? 137 ARG B CB  1 
ATOM   6035  C  CG  . ARG D 1 144 ? 157.227 129.018 125.605 1.00 52.58  ? 137 ARG B CG  1 
ATOM   6036  C  CD  . ARG D 1 144 ? 158.605 129.655 125.711 1.00 52.58  ? 137 ARG B CD  1 
ATOM   6037  N  NE  . ARG D 1 144 ? 159.658 128.777 125.214 1.00 52.58  ? 137 ARG B NE  1 
ATOM   6038  C  CZ  . ARG D 1 144 ? 160.702 129.184 124.505 1.00 52.58  ? 137 ARG B CZ  1 
ATOM   6039  N  NH1 . ARG D 1 144 ? 160.865 130.457 124.184 1.00 52.58  ? 137 ARG B NH1 1 
ATOM   6040  N  NH2 . ARG D 1 144 ? 161.605 128.292 124.108 1.00 52.58  ? 137 ARG B NH2 1 
ATOM   6041  N  N   . THR D 1 145 ? 152.652 130.813 125.693 1.00 45.74  ? 138 THR B N   1 
ATOM   6042  C  CA  . THR D 1 145 ? 151.678 131.847 126.012 1.00 45.74  ? 138 THR B CA  1 
ATOM   6043  C  C   . THR D 1 145 ? 150.287 131.315 125.704 1.00 45.74  ? 138 THR B C   1 
ATOM   6044  O  O   . THR D 1 145 ? 150.105 130.508 124.791 1.00 45.74  ? 138 THR B O   1 
ATOM   6045  C  CB  . THR D 1 145 ? 151.936 133.139 125.223 1.00 45.74  ? 138 THR B CB  1 
ATOM   6046  O  OG1 . THR D 1 145 ? 153.342 133.409 125.185 1.00 45.74  ? 138 THR B OG1 1 
ATOM   6047  C  CG2 . THR D 1 145 ? 151.224 134.314 125.876 1.00 45.74  ? 138 THR B CG2 1 
ATOM   6048  N  N   . TRP D 1 146 ? 149.303 131.779 126.472 1.00 34.60  ? 139 TRP B N   1 
ATOM   6049  C  CA  . TRP D 1 146 ? 147.922 131.326 126.341 1.00 34.60  ? 139 TRP B CA  1 
ATOM   6050  C  C   . TRP D 1 146 ? 147.149 132.349 125.522 1.00 34.60  ? 139 TRP B C   1 
ATOM   6051  O  O   . TRP D 1 146 ? 146.978 133.495 125.950 1.00 34.60  ? 139 TRP B O   1 
ATOM   6052  C  CB  . TRP D 1 146 ? 147.280 131.128 127.711 1.00 34.60  ? 139 TRP B CB  1 
ATOM   6053  C  CG  . TRP D 1 146 ? 146.265 130.035 127.736 1.00 34.60  ? 139 TRP B CG  1 
ATOM   6054  C  CD1 . TRP D 1 146 ? 146.477 128.734 128.071 1.00 34.60  ? 139 TRP B CD1 1 
ATOM   6055  C  CD2 . TRP D 1 146 ? 144.876 130.145 127.412 1.00 34.60  ? 139 TRP B CD2 1 
ATOM   6056  N  NE1 . TRP D 1 146 ? 145.308 128.023 127.972 1.00 34.60  ? 139 TRP B NE1 1 
ATOM   6057  C  CE2 . TRP D 1 146 ? 144.309 128.868 127.570 1.00 34.60  ? 139 TRP B CE2 1 
ATOM   6058  C  CE3 . TRP D 1 146 ? 144.057 131.198 127.004 1.00 34.60  ? 139 TRP B CE3 1 
ATOM   6059  C  CZ2 . TRP D 1 146 ? 142.965 128.617 127.337 1.00 34.60  ? 139 TRP B CZ2 1 
ATOM   6060  C  CZ3 . TRP D 1 146 ? 142.723 130.946 126.773 1.00 34.60  ? 139 TRP B CZ3 1 
ATOM   6061  C  CH2 . TRP D 1 146 ? 142.190 129.667 126.940 1.00 34.60  ? 139 TRP B CH2 1 
ATOM   6062  N  N   . THR D 1 147 ? 146.680 131.935 124.349 1.00 38.22  ? 140 THR B N   1 
ATOM   6063  C  CA  . THR D 1 147 ? 145.907 132.788 123.457 1.00 38.22  ? 140 THR B CA  1 
ATOM   6064  C  C   . THR D 1 147 ? 144.569 132.126 123.165 1.00 38.22  ? 140 THR B C   1 
ATOM   6065  O  O   . THR D 1 147 ? 144.526 130.957 122.769 1.00 38.22  ? 140 THR B O   1 
ATOM   6066  C  CB  . THR D 1 147 ? 146.659 133.044 122.149 1.00 38.22  ? 140 THR B CB  1 
ATOM   6067  O  OG1 . THR D 1 147 ? 146.623 131.863 121.340 1.00 38.22  ? 140 THR B OG1 1 
ATOM   6068  C  CG2 . THR D 1 147 ? 148.106 133.415 122.425 1.00 38.22  ? 140 THR B CG2 1 
ATOM   6069  N  N   . TRP D 1 148 ? 143.486 132.877 123.349 1.00 35.48  ? 141 TRP B N   1 
ATOM   6070  C  CA  . TRP D 1 148 ? 142.156 132.356 123.083 1.00 35.48  ? 141 TRP B CA  1 
ATOM   6071  C  C   . TRP D 1 148 ? 141.971 132.106 121.587 1.00 35.48  ? 141 TRP B C   1 
ATOM   6072  O  O   . TRP D 1 148 ? 142.813 132.457 120.756 1.00 35.48  ? 141 TRP B O   1 
ATOM   6073  C  CB  . TRP D 1 148 ? 141.087 133.327 123.579 1.00 35.48  ? 141 TRP B CB  1 
ATOM   6074  C  CG  . TRP D 1 148 ? 141.086 133.557 125.057 1.00 35.48  ? 141 TRP B CG  1 
ATOM   6075  C  CD1 . TRP D 1 148 ? 141.992 134.279 125.774 1.00 35.48  ? 141 TRP B CD1 1 
ATOM   6076  C  CD2 . TRP D 1 148 ? 140.112 133.090 125.999 1.00 35.48  ? 141 TRP B CD2 1 
ATOM   6077  N  NE1 . TRP D 1 148 ? 141.652 134.278 127.104 1.00 35.48  ? 141 TRP B NE1 1 
ATOM   6078  C  CE2 . TRP D 1 148 ? 140.500 133.556 127.267 1.00 35.48  ? 141 TRP B CE2 1 
ATOM   6079  C  CE3 . TRP D 1 148 ? 138.953 132.317 125.893 1.00 35.48  ? 141 TRP B CE3 1 
ATOM   6080  C  CZ2 . TRP D 1 148 ? 139.773 133.275 128.419 1.00 35.48  ? 141 TRP B CZ2 1 
ATOM   6081  C  CZ3 . TRP D 1 148 ? 138.233 132.040 127.036 1.00 35.48  ? 141 TRP B CZ3 1 
ATOM   6082  C  CH2 . TRP D 1 148 ? 138.645 132.516 128.282 1.00 35.48  ? 141 TRP B CH2 1 
ATOM   6083  N  N   . GLY D 1 149 ? 140.842 131.492 121.244 1.00 37.39  ? 142 GLY B N   1 
ATOM   6084  C  CA  . GLY D 1 149 ? 140.477 131.294 119.862 1.00 37.39  ? 142 GLY B CA  1 
ATOM   6085  C  C   . GLY D 1 149 ? 140.755 129.892 119.361 1.00 37.39  ? 142 GLY B C   1 
ATOM   6086  O  O   . GLY D 1 149 ? 141.545 129.141 119.941 1.00 37.39  ? 142 GLY B O   1 
ATOM   6087  N  N   . PRO D 1 150 ? 140.101 129.515 118.258 1.00 44.32  ? 143 PRO B N   1 
ATOM   6088  C  CA  . PRO D 1 150 ? 140.298 128.164 117.712 1.00 44.32  ? 143 PRO B CA  1 
ATOM   6089  C  C   . PRO D 1 150 ? 141.707 127.897 117.213 1.00 44.32  ? 143 PRO B C   1 
ATOM   6090  O  O   . PRO D 1 150 ? 142.082 126.727 117.075 1.00 44.32  ? 143 PRO B O   1 
ATOM   6091  C  CB  . PRO D 1 150 ? 139.282 128.097 116.564 1.00 44.32  ? 143 PRO B CB  1 
ATOM   6092  C  CG  . PRO D 1 150 ? 139.051 129.521 116.186 1.00 44.32  ? 143 PRO B CG  1 
ATOM   6093  C  CD  . PRO D 1 150 ? 139.148 130.304 117.460 1.00 44.32  ? 143 PRO B CD  1 
ATOM   6094  N  N   . CYS D 1 151 ? 142.495 128.931 116.932 1.00 49.65  ? 144 CYS B N   1 
ATOM   6095  C  CA  . CYS D 1 151 ? 143.864 128.764 116.465 1.00 49.65  ? 144 CYS B CA  1 
ATOM   6096  C  C   . CYS D 1 151 ? 144.887 128.926 117.582 1.00 49.65  ? 144 CYS B C   1 
ATOM   6097  O  O   . CYS D 1 151 ? 146.091 128.937 117.310 1.00 49.65  ? 144 CYS B O   1 
ATOM   6098  C  CB  . CYS D 1 151 ? 144.159 129.753 115.336 1.00 49.65  ? 144 CYS B CB  1 
ATOM   6099  S  SG  . CYS D 1 151 ? 144.719 131.384 115.882 1.00 49.65  ? 144 CYS B SG  1 
ATOM   6100  N  N   . GLY D 1 152 ? 144.438 129.044 118.830 1.00 46.57  ? 145 GLY B N   1 
ATOM   6101  C  CA  . GLY D 1 152 ? 145.322 129.290 119.949 1.00 46.57  ? 145 GLY B CA  1 
ATOM   6102  C  C   . GLY D 1 152 ? 145.992 128.030 120.460 1.00 46.57  ? 145 GLY B C   1 
ATOM   6103  O  O   . GLY D 1 152 ? 145.857 126.940 119.903 1.00 46.57  ? 145 GLY B O   1 
ATOM   6104  N  N   . GLN D 1 153 ? 146.735 128.200 121.553 1.00 45.62  ? 146 GLN B N   1 
ATOM   6105  C  CA  . GLN D 1 153 ? 147.450 127.101 122.183 1.00 45.62  ? 146 GLN B CA  1 
ATOM   6106  C  C   . GLN D 1 153 ? 147.569 127.375 123.674 1.00 45.62  ? 146 GLN B C   1 
ATOM   6107  O  O   . GLN D 1 153 ? 147.702 128.525 124.098 1.00 45.62  ? 146 GLN B O   1 
ATOM   6108  C  CB  . GLN D 1 153 ? 148.840 126.909 121.565 1.00 45.62  ? 146 GLN B CB  1 
ATOM   6109  C  CG  . GLN D 1 153 ? 148.874 125.925 120.409 1.00 45.62  ? 146 GLN B CG  1 
ATOM   6110  C  CD  . GLN D 1 153 ? 150.018 126.191 119.453 1.00 45.62  ? 146 GLN B CD  1 
ATOM   6111  O  OE1 . GLN D 1 153 ? 151.064 126.706 119.849 1.00 45.62  ? 146 GLN B OE1 1 
ATOM   6112  N  NE2 . GLN D 1 153 ? 149.826 125.841 118.188 1.00 45.62  ? 146 GLN B NE2 1 
ATOM   6113  N  N   . GLY D 1 154 ? 147.520 126.305 124.466 1.00 40.96  ? 147 GLY B N   1 
ATOM   6114  C  CA  . GLY D 1 154 ? 147.611 126.420 125.910 1.00 40.96  ? 147 GLY B CA  1 
ATOM   6115  C  C   . GLY D 1 154 ? 146.672 125.482 126.640 1.00 40.96  ? 147 GLY B C   1 
ATOM   6116  O  O   . GLY D 1 154 ? 145.505 125.355 126.260 1.00 40.96  ? 147 GLY B O   1 
ATOM   6117  N  N   . ALA D 1 155 ? 147.158 124.831 127.692 1.00 33.22  ? 148 ALA B N   1 
ATOM   6118  C  CA  . ALA D 1 155 ? 146.403 123.784 128.362 1.00 33.22  ? 148 ALA B CA  1 
ATOM   6119  C  C   . ALA D 1 155 ? 145.518 124.351 129.472 1.00 33.22  ? 148 ALA B C   1 
ATOM   6120  O  O   . ALA D 1 155 ? 145.608 125.521 129.852 1.00 33.22  ? 148 ALA B O   1 
ATOM   6121  C  CB  . ALA D 1 155 ? 147.349 122.725 128.921 1.00 33.22  ? 148 ALA B CB  1 
ATOM   6122  N  N   . ILE D 1 156 ? 144.655 123.486 130.005 1.00 29.84  ? 149 ILE B N   1 
ATOM   6123  C  CA  . ILE D 1 156 ? 143.622 123.879 130.955 1.00 29.84  ? 149 ILE B CA  1 
ATOM   6124  C  C   . ILE D 1 156 ? 143.713 123.002 132.197 1.00 29.84  ? 149 ILE B C   1 
ATOM   6125  O  O   . ILE D 1 156 ? 143.800 121.774 132.090 1.00 29.84  ? 149 ILE B O   1 
ATOM   6126  C  CB  . ILE D 1 156 ? 142.212 123.782 130.343 1.00 29.84  ? 149 ILE B CB  1 
ATOM   6127  C  CG1 . ILE D 1 156 ? 142.128 124.562 129.030 1.00 29.84  ? 149 ILE B CG1 1 
ATOM   6128  C  CG2 . ILE D 1 156 ? 141.173 124.281 131.327 1.00 29.84  ? 149 ILE B CG2 1 
ATOM   6129  C  CD1 . ILE D 1 156 ? 142.353 123.718 127.802 1.00 29.84  ? 149 ILE B CD1 1 
ATOM   6130  N  N   . LEU D 1 157 ? 143.691 123.632 133.365 1.00 30.42  ? 150 LEU B N   1 
ATOM   6131  C  CA  . LEU D 1 157 ? 143.533 122.958 134.646 1.00 30.42  ? 150 LEU B CA  1 
ATOM   6132  C  C   . LEU D 1 157 ? 142.077 122.930 135.078 1.00 30.42  ? 150 LEU B C   1 
ATOM   6133  O  O   . LEU D 1 157 ? 141.243 123.708 134.611 1.00 30.42  ? 150 LEU B O   1 
ATOM   6134  C  CB  . LEU D 1 157 ? 144.369 123.626 135.740 1.00 30.42  ? 150 LEU B CB  1 
ATOM   6135  C  CG  . LEU D 1 157 ? 145.886 123.594 135.615 1.00 30.42  ? 150 LEU B CG  1 
ATOM   6136  C  CD1 . LEU D 1 157 ? 146.525 124.408 136.680 1.00 30.42  ? 150 LEU B CD1 1 
ATOM   6137  C  CD2 . LEU D 1 157 ? 146.367 122.157 135.696 1.00 30.42  ? 150 LEU B CD2 1 
ATOM   6138  N  N   . LEU D 1 158 ? 141.788 122.014 135.994 1.00 30.68  ? 151 LEU B N   1 
ATOM   6139  C  CA  . LEU D 1 158 ? 140.473 121.877 136.590 1.00 30.68  ? 151 LEU B CA  1 
ATOM   6140  C  C   . LEU D 1 158 ? 140.599 122.032 138.097 1.00 30.68  ? 151 LEU B C   1 
ATOM   6141  O  O   . LEU D 1 158 ? 141.446 121.390 138.726 1.00 30.68  ? 151 LEU B O   1 
ATOM   6142  C  CB  . LEU D 1 158 ? 139.862 120.517 136.258 1.00 30.68  ? 151 LEU B CB  1 
ATOM   6143  C  CG  . LEU D 1 158 ? 138.863 120.507 135.108 1.00 30.68  ? 151 LEU B CG  1 
ATOM   6144  C  CD1 . LEU D 1 158 ? 138.767 119.117 134.517 1.00 30.68  ? 151 LEU B CD1 1 
ATOM   6145  C  CD2 . LEU D 1 158 ? 137.520 121.000 135.568 1.00 30.68  ? 151 LEU B CD2 1 
ATOM   6146  N  N   . VAL D 1 159 ? 139.765 122.886 138.675 1.00 34.24  ? 152 VAL B N   1 
ATOM   6147  C  CA  . VAL D 1 159 ? 139.768 123.076 140.120 1.00 34.24  ? 152 VAL B CA  1 
ATOM   6148  C  C   . VAL D 1 159 ? 139.232 121.806 140.765 1.00 34.24  ? 152 VAL B C   1 
ATOM   6149  O  O   . VAL D 1 159 ? 138.075 121.431 140.556 1.00 34.24  ? 152 VAL B O   1 
ATOM   6150  C  CB  . VAL D 1 159 ? 138.932 124.296 140.523 1.00 34.24  ? 152 VAL B CB  1 
ATOM   6151  C  CG1 . VAL D 1 159 ? 138.890 124.427 142.033 1.00 34.24  ? 152 VAL B CG1 1 
ATOM   6152  C  CG2 . VAL D 1 159 ? 139.495 125.548 139.887 1.00 34.24  ? 152 VAL B CG2 1 
ATOM   6153  N  N   . ASN D 1 160 ? 140.074 121.137 141.548 1.00 39.96  ? 153 ASN B N   1 
ATOM   6154  C  CA  . ASN D 1 160 ? 139.687 119.890 142.204 1.00 39.96  ? 153 ASN B CA  1 
ATOM   6155  C  C   . ASN D 1 160 ? 138.781 120.238 143.379 1.00 39.96  ? 153 ASN B C   1 
ATOM   6156  O  O   . ASN D 1 160 ? 139.194 120.289 144.538 1.00 39.96  ? 153 ASN B O   1 
ATOM   6157  C  CB  . ASN D 1 160 ? 140.918 119.114 142.650 1.00 39.96  ? 153 ASN B CB  1 
ATOM   6158  C  CG  . ASN D 1 160 ? 140.745 117.621 142.508 1.00 39.96  ? 153 ASN B CG  1 
ATOM   6159  O  OD1 . ASN D 1 160 ? 139.786 117.043 143.016 1.00 39.96  ? 153 ASN B OD1 1 
ATOM   6160  N  ND2 . ASN D 1 160 ? 141.676 116.984 141.811 1.00 39.96  ? 153 ASN B ND2 1 
ATOM   6161  N  N   . CYS D 1 161 ? 137.512 120.489 143.062 1.00 40.16  ? 154 CYS B N   1 
ATOM   6162  C  CA  . CYS D 1 161 ? 136.530 120.899 144.056 1.00 40.16  ? 154 CYS B CA  1 
ATOM   6163  C  C   . CYS D 1 161 ? 135.563 119.784 144.431 1.00 40.16  ? 154 CYS B C   1 
ATOM   6164  O  O   . CYS D 1 161 ? 134.567 120.048 145.111 1.00 40.16  ? 154 CYS B O   1 
ATOM   6165  C  CB  . CYS D 1 161 ? 135.750 122.115 143.557 1.00 40.16  ? 154 CYS B CB  1 
ATOM   6166  S  SG  . CYS D 1 161 ? 135.302 122.058 141.813 1.00 40.16  ? 154 CYS B SG  1 
ATOM   6167  N  N   . ASP D 1 162 ? 135.827 118.552 144.015 1.00 46.07  ? 155 ASP B N   1 
ATOM   6168  C  CA  . ASP D 1 162 ? 134.961 117.430 144.332 1.00 46.07  ? 155 ASP B CA  1 
ATOM   6169  C  C   . ASP D 1 162 ? 135.552 116.618 145.482 1.00 46.07  ? 155 ASP B C   1 
ATOM   6170  O  O   . ASP D 1 162 ? 136.584 116.964 146.059 1.00 46.07  ? 155 ASP B O   1 
ATOM   6171  C  CB  . ASP D 1 162 ? 134.733 116.562 143.091 1.00 46.07  ? 155 ASP B CB  1 
ATOM   6172  C  CG  . ASP D 1 162 ? 136.012 115.923 142.574 1.00 46.07  ? 155 ASP B CG  1 
ATOM   6173  O  OD1 . ASP D 1 162 ? 137.098 116.211 143.114 1.00 46.07  ? 155 ASP B OD1 1 
ATOM   6174  O  OD2 . ASP D 1 162 ? 135.929 115.124 141.618 1.00 46.07  ? 155 ASP B OD2 1 
ATOM   6175  N  N   . ARG D 1 163 ? 134.879 115.519 145.821 1.00 52.25  ? 156 ARG B N   1 
ATOM   6176  C  CA  . ARG D 1 163 ? 135.360 114.566 146.821 1.00 52.25  ? 156 ARG B CA  1 
ATOM   6177  C  C   . ARG D 1 163 ? 135.203 113.157 146.245 1.00 52.25  ? 156 ARG B C   1 
ATOM   6178  O  O   . ARG D 1 163 ? 134.120 112.569 146.266 1.00 52.25  ? 156 ARG B O   1 
ATOM   6179  C  CB  . ARG D 1 163 ? 134.627 114.738 148.161 1.00 52.25  ? 156 ARG B CB  1 
ATOM   6180  C  CG  . ARG D 1 163 ? 133.111 114.669 148.084 1.00 52.25  ? 156 ARG B CG  1 
ATOM   6181  C  CD  . ARG D 1 163 ? 132.493 114.197 149.390 1.00 52.25  ? 156 ARG B CD  1 
ATOM   6182  N  NE  . ARG D 1 163 ? 132.329 115.269 150.362 1.00 52.25  ? 156 ARG B NE  1 
ATOM   6183  C  CZ  . ARG D 1 163 ? 131.348 115.321 151.252 1.00 52.25  ? 156 ARG B CZ  1 
ATOM   6184  N  NH1 . ARG D 1 163 ? 130.420 114.380 151.314 1.00 52.25  ? 156 ARG B NH1 1 
ATOM   6185  N  NH2 . ARG D 1 163 ? 131.296 116.341 152.104 1.00 52.25  ? 156 ARG B NH2 1 
ATOM   6186  N  N   . ASP D 1 164 ? 136.297 112.620 145.705 1.00 54.83  ? 157 ASP B N   1 
ATOM   6187  C  CA  . ASP D 1 164 ? 136.296 111.255 145.199 1.00 54.83  ? 157 ASP B CA  1 
ATOM   6188  C  C   . ASP D 1 164 ? 136.501 110.221 146.296 1.00 54.83  ? 157 ASP B C   1 
ATOM   6189  O  O   . ASP D 1 164 ? 136.411 109.021 146.016 1.00 54.83  ? 157 ASP B O   1 
ATOM   6190  C  CB  . ASP D 1 164 ? 137.373 111.087 144.126 1.00 54.83  ? 157 ASP B CB  1 
ATOM   6191  C  CG  . ASP D 1 164 ? 137.105 111.931 142.900 1.00 54.83  ? 157 ASP B CG  1 
ATOM   6192  O  OD1 . ASP D 1 164 ? 136.257 111.532 142.076 1.00 54.83  ? 157 ASP B OD1 1 
ATOM   6193  O  OD2 . ASP D 1 164 ? 137.735 112.999 142.767 1.00 54.83  ? 157 ASP B OD2 1 
ATOM   6194  N  N   . ASN D 1 165 ? 136.778 110.652 147.521 1.00 65.80  ? 158 ASN B N   1 
ATOM   6195  C  CA  . ASN D 1 165 ? 136.894 109.742 148.651 1.00 65.80  ? 158 ASN B CA  1 
ATOM   6196  C  C   . ASN D 1 165 ? 135.550 109.644 149.358 1.00 65.80  ? 158 ASN B C   1 
ATOM   6197  O  O   . ASN D 1 165 ? 134.953 110.664 149.716 1.00 65.80  ? 158 ASN B O   1 
ATOM   6198  C  CB  . ASN D 1 165 ? 137.972 110.222 149.623 1.00 65.80  ? 158 ASN B CB  1 
ATOM   6199  C  CG  . ASN D 1 165 ? 138.413 109.137 150.581 1.00 65.80  ? 158 ASN B CG  1 
ATOM   6200  O  OD1 . ASN D 1 165 ? 139.083 109.407 151.577 1.00 65.80  ? 158 ASN B OD1 1 
ATOM   6201  N  ND2 . ASN D 1 165 ? 138.040 107.898 150.285 1.00 65.80  ? 158 ASN B ND2 1 
ATOM   6202  N  N   . LEU D 1 166 ? 135.078 108.417 149.557 1.00 72.97  ? 159 LEU B N   1 
ATOM   6203  C  CA  . LEU D 1 166 ? 133.799 108.174 150.207 1.00 72.97  ? 159 LEU B CA  1 
ATOM   6204  C  C   . LEU D 1 166 ? 133.899 108.173 151.726 1.00 72.97  ? 159 LEU B C   1 
ATOM   6205  O  O   . LEU D 1 166 ? 132.864 108.128 152.400 1.00 72.97  ? 159 LEU B O   1 
ATOM   6206  C  CB  . LEU D 1 166 ? 133.212 106.843 149.728 1.00 72.97  ? 159 LEU B CB  1 
ATOM   6207  C  CG  . LEU D 1 166 ? 132.910 106.750 148.232 1.00 72.97  ? 159 LEU B CG  1 
ATOM   6208  C  CD1 . LEU D 1 166 ? 132.060 105.528 147.933 1.00 72.97  ? 159 LEU B CD1 1 
ATOM   6209  C  CD2 . LEU D 1 166 ? 132.223 108.015 147.749 1.00 72.97  ? 159 LEU B CD2 1 
ATOM   6210  N  N   . GLU D 1 167 ? 135.111 108.221 152.280 1.00 74.33  ? 160 GLU B N   1 
ATOM   6211  C  CA  . GLU D 1 167 ? 135.314 108.249 153.723 1.00 74.33  ? 160 GLU B CA  1 
ATOM   6212  C  C   . GLU D 1 167 ? 135.971 109.548 154.175 1.00 74.33  ? 160 GLU B C   1 
ATOM   6213  O  O   . GLU D 1 167 ? 136.539 109.608 155.270 1.00 74.33  ? 160 GLU B O   1 
ATOM   6214  C  CB  . GLU D 1 167 ? 136.148 107.043 154.167 1.00 74.33  ? 160 GLU B CB  1 
ATOM   6215  C  CG  . GLU D 1 167 ? 135.856 106.561 155.582 1.00 74.33  ? 160 GLU B CG  1 
ATOM   6216  C  CD  . GLU D 1 167 ? 134.501 105.888 155.710 1.00 74.33  ? 160 GLU B CD  1 
ATOM   6217  O  OE1 . GLU D 1 167 ? 133.869 105.604 154.670 1.00 74.33  ? 160 GLU B OE1 1 
ATOM   6218  O  OE2 . GLU D 1 167 ? 134.066 105.642 156.855 1.00 74.33  ? 160 GLU B OE2 1 
ATOM   6219  N  N   . SER D 1 168 ? 135.900 110.591 153.356 1.00 69.09  ? 161 SER B N   1 
ATOM   6220  C  CA  . SER D 1 168 ? 136.485 111.886 153.665 1.00 69.09  ? 161 SER B CA  1 
ATOM   6221  C  C   . SER D 1 168 ? 135.382 112.931 153.769 1.00 69.09  ? 161 SER B C   1 
ATOM   6222  O  O   . SER D 1 168 ? 134.279 112.764 153.242 1.00 69.09  ? 161 SER B O   1 
ATOM   6223  C  CB  . SER D 1 168 ? 137.511 112.297 152.602 1.00 69.09  ? 161 SER B CB  1 
ATOM   6224  O  OG  . SER D 1 168 ? 138.682 111.504 152.689 1.00 69.09  ? 161 SER B OG  1 
ATOM   6225  N  N   . SER D 1 169 ? 135.694 114.024 154.464 1.00 64.31  ? 162 SER B N   1 
ATOM   6226  C  CA  . SER D 1 169 ? 134.756 115.123 154.667 1.00 64.31  ? 162 SER B CA  1 
ATOM   6227  C  C   . SER D 1 169 ? 135.455 116.447 154.358 1.00 64.31  ? 162 SER B C   1 
ATOM   6228  O  O   . SER D 1 169 ? 135.365 117.420 155.105 1.00 64.31  ? 162 SER B O   1 
ATOM   6229  C  CB  . SER D 1 169 ? 134.198 115.110 156.088 1.00 64.31  ? 162 SER B CB  1 
ATOM   6230  O  OG  . SER D 1 169 ? 135.244 115.087 157.044 1.00 64.31  ? 162 SER B OG  1 
ATOM   6231  N  N   . ALA D 1 170 ? 136.164 116.478 153.231 1.00 56.36  ? 163 ALA B N   1 
ATOM   6232  C  CA  . ALA D 1 170 ? 136.882 117.676 152.825 1.00 56.36  ? 163 ALA B CA  1 
ATOM   6233  C  C   . ALA D 1 170 ? 137.064 117.659 151.317 1.00 56.36  ? 163 ALA B C   1 
ATOM   6234  O  O   . ALA D 1 170 ? 137.183 116.590 150.715 1.00 56.36  ? 163 ALA B O   1 
ATOM   6235  C  CB  . ALA D 1 170 ? 138.242 117.774 153.523 1.00 56.36  ? 163 ALA B CB  1 
ATOM   6236  N  N   . MET D 1 171 ? 137.076 118.848 150.715 1.00 53.33  ? 164 MET B N   1 
ATOM   6237  C  CA  . MET D 1 171 ? 137.421 118.963 149.306 1.00 53.33  ? 164 MET B CA  1 
ATOM   6238  C  C   . MET D 1 171 ? 138.841 118.460 149.096 1.00 53.33  ? 164 MET B C   1 
ATOM   6239  O  O   . MET D 1 171 ? 139.756 118.824 149.840 1.00 53.33  ? 164 MET B O   1 
ATOM   6240  C  CB  . MET D 1 171 ? 137.279 120.411 148.840 1.00 53.33  ? 164 MET B CB  1 
ATOM   6241  C  CG  . MET D 1 171 ? 135.867 120.774 148.402 1.00 53.33  ? 164 MET B CG  1 
ATOM   6242  S  SD  . MET D 1 171 ? 135.725 122.319 147.475 1.00 53.33  ? 164 MET B SD  1 
ATOM   6243  C  CE  . MET D 1 171 ? 137.438 122.807 147.318 1.00 53.33  ? 164 MET B CE  1 
ATOM   6244  N  N   . ASP D 1 172 ? 139.028 117.628 148.074 1.00 53.82  ? 165 ASP B N   1 
ATOM   6245  C  CA  . ASP D 1 172 ? 140.235 116.816 147.981 1.00 53.82  ? 165 ASP B CA  1 
ATOM   6246  C  C   . ASP D 1 172 ? 141.468 117.639 147.629 1.00 53.82  ? 165 ASP B C   1 
ATOM   6247  O  O   . ASP D 1 172 ? 142.582 117.108 147.603 1.00 53.82  ? 165 ASP B O   1 
ATOM   6248  C  CB  . ASP D 1 172 ? 140.039 115.696 146.960 1.00 53.82  ? 165 ASP B CB  1 
ATOM   6249  C  CG  . ASP D 1 172 ? 140.712 114.405 147.383 1.00 53.82  ? 165 ASP B CG  1 
ATOM   6250  O  OD1 . ASP D 1 172 ? 140.036 113.355 147.384 1.00 53.82  ? 165 ASP B OD1 1 
ATOM   6251  O  OD2 . ASP D 1 172 ? 141.914 114.440 147.716 1.00 53.82  ? 165 ASP B OD2 1 
ATOM   6252  N  N   . CYS D 1 173 ? 141.289 118.930 147.357 1.00 51.54  ? 166 CYS B N   1 
ATOM   6253  C  CA  . CYS D 1 173 ? 142.410 119.824 147.114 1.00 51.54  ? 166 CYS B CA  1 
ATOM   6254  C  C   . CYS D 1 173 ? 142.888 120.524 148.378 1.00 51.54  ? 166 CYS B C   1 
ATOM   6255  O  O   . CYS D 1 173 ? 143.854 121.292 148.316 1.00 51.54  ? 166 CYS B O   1 
ATOM   6256  C  CB  . CYS D 1 173 ? 142.038 120.870 146.059 1.00 51.54  ? 166 CYS B CB  1 
ATOM   6257  S  SG  . CYS D 1 173 ? 140.788 122.045 146.601 1.00 51.54  ? 166 CYS B SG  1 
ATOM   6258  N  N   . GLU D 1 174 ? 142.241 120.281 149.519 1.00 58.18  ? 167 GLU B N   1 
ATOM   6259  C  CA  . GLU D 1 174 ? 142.638 120.911 150.773 1.00 58.18  ? 167 GLU B CA  1 
ATOM   6260  C  C   . GLU D 1 174 ? 143.895 120.297 151.373 1.00 58.18  ? 167 GLU B C   1 
ATOM   6261  O  O   . GLU D 1 174 ? 144.745 121.036 151.882 1.00 58.18  ? 167 GLU B O   1 
ATOM   6262  C  CB  . GLU D 1 174 ? 141.489 120.829 151.781 1.00 58.18  ? 167 GLU B CB  1 
ATOM   6263  C  CG  . GLU D 1 174 ? 141.927 120.659 153.225 1.00 58.18  ? 167 GLU B CG  1 
ATOM   6264  C  CD  . GLU D 1 174 ? 140.756 120.627 154.184 1.00 58.18  ? 167 GLU B CD  1 
ATOM   6265  O  OE1 . GLU D 1 174 ? 139.887 121.520 154.094 1.00 58.18  ? 167 GLU B OE1 1 
ATOM   6266  O  OE2 . GLU D 1 174 ? 140.703 119.710 155.030 1.00 58.18  ? 167 GLU B OE2 1 
ATOM   6267  N  N   . ASP D 1 175 ? 144.038 118.978 151.323 1.00 56.63  ? 168 ASP B N   1 
ATOM   6268  C  CA  . ASP D 1 175 ? 145.182 118.290 151.892 1.00 56.63  ? 168 ASP B CA  1 
ATOM   6269  C  C   . ASP D 1 175 ? 146.312 118.225 150.864 1.00 56.63  ? 168 ASP B C   1 
ATOM   6270  O  O   . ASP D 1 175 ? 146.265 118.868 149.813 1.00 56.63  ? 168 ASP B O   1 
ATOM   6271  C  CB  . ASP D 1 175 ? 144.763 116.903 152.382 1.00 56.63  ? 168 ASP B CB  1 
ATOM   6272  C  CG  . ASP D 1 175 ? 143.968 116.134 151.347 1.00 56.63  ? 168 ASP B CG  1 
ATOM   6273  O  OD1 . ASP D 1 175 ? 143.752 116.669 150.240 1.00 56.63  ? 168 ASP B OD1 1 
ATOM   6274  O  OD2 . ASP D 1 175 ? 143.552 114.995 151.645 1.00 56.63  ? 168 ASP B OD2 1 
ATOM   6275  N  N   . ASP D 1 176 ? 147.343 117.442 151.168 1.00 57.45  ? 169 ASP B N   1 
ATOM   6276  C  CA  . ASP D 1 176 ? 148.511 117.294 150.304 1.00 57.45  ? 169 ASP B CA  1 
ATOM   6277  C  C   . ASP D 1 176 ? 148.778 115.824 150.016 1.00 57.45  ? 169 ASP B C   1 
ATOM   6278  O  O   . ASP D 1 176 ? 149.901 115.333 150.135 1.00 57.45  ? 169 ASP B O   1 
ATOM   6279  C  CB  . ASP D 1 176 ? 149.741 117.954 150.923 1.00 57.45  ? 169 ASP B CB  1 
ATOM   6280  C  CG  . ASP D 1 176 ? 149.905 117.626 152.394 1.00 57.45  ? 169 ASP B CG  1 
ATOM   6281  O  OD1 . ASP D 1 176 ? 149.616 116.479 152.790 1.00 57.45  ? 169 ASP B OD1 1 
ATOM   6282  O  OD2 . ASP D 1 176 ? 150.328 118.519 153.156 1.00 57.45  ? 169 ASP B OD2 1 
ATOM   6283  N  N   . GLU D 1 177 ? 147.730 115.094 149.638 1.00 59.64  ? 170 GLU B N   1 
ATOM   6284  C  CA  . GLU D 1 177 ? 147.868 113.691 149.280 1.00 59.64  ? 170 GLU B CA  1 
ATOM   6285  C  C   . GLU D 1 177 ? 146.797 113.326 148.265 1.00 59.64  ? 170 GLU B C   1 
ATOM   6286  O  O   . GLU D 1 177 ? 145.758 113.983 148.164 1.00 59.64  ? 170 GLU B O   1 
ATOM   6287  C  CB  . GLU D 1 177 ? 147.766 112.775 150.507 1.00 59.64  ? 170 GLU B CB  1 
ATOM   6288  C  CG  . GLU D 1 177 ? 149.079 112.530 151.237 1.00 59.64  ? 170 GLU B CG  1 
ATOM   6289  C  CD  . GLU D 1 177 ? 150.070 111.716 150.421 1.00 59.64  ? 170 GLU B CD  1 
ATOM   6290  O  OE1 . GLU D 1 177 ? 149.657 111.087 149.424 1.00 59.64  ? 170 GLU B OE1 1 
ATOM   6291  O  OE2 . GLU D 1 177 ? 151.266 111.705 150.780 1.00 59.64  ? 170 GLU B OE2 1 
ATOM   6292  N  N   . VAL D 1 178 ? 147.066 112.263 147.512 1.00 56.81  ? 171 VAL B N   1 
ATOM   6293  C  CA  . VAL D 1 178 ? 146.103 111.686 146.582 1.00 56.81  ? 171 VAL B CA  1 
ATOM   6294  C  C   . VAL D 1 178 ? 145.591 110.395 147.202 1.00 56.81  ? 171 VAL B C   1 
ATOM   6295  O  O   . VAL D 1 178 ? 146.344 109.425 147.346 1.00 56.81  ? 171 VAL B O   1 
ATOM   6296  C  CB  . VAL D 1 178 ? 146.735 111.432 145.206 1.00 56.81  ? 171 VAL B CB  1 
ATOM   6297  C  CG1 . VAL D 1 178 ? 145.665 111.103 144.187 1.00 56.81  ? 171 VAL B CG1 1 
ATOM   6298  C  CG2 . VAL D 1 178 ? 147.544 112.636 144.767 1.00 56.81  ? 171 VAL B CG2 1 
ATOM   6299  N  N   . LEU D 1 179 ? 144.312 110.378 147.570 1.00 59.71  ? 172 LEU B N   1 
ATOM   6300  C  CA  . LEU D 1 179 ? 143.764 109.296 148.377 1.00 59.71  ? 172 LEU B CA  1 
ATOM   6301  C  C   . LEU D 1 179 ? 143.102 108.192 147.564 1.00 59.71  ? 172 LEU B C   1 
ATOM   6302  O  O   . LEU D 1 179 ? 142.772 107.148 148.136 1.00 59.71  ? 172 LEU B O   1 
ATOM   6303  C  CB  . LEU D 1 179 ? 142.752 109.849 149.388 1.00 59.71  ? 172 LEU B CB  1 
ATOM   6304  C  CG  . LEU D 1 179 ? 143.307 110.712 150.523 1.00 59.71  ? 172 LEU B CG  1 
ATOM   6305  C  CD1 . LEU D 1 179 ? 144.656 110.186 150.997 1.00 59.71  ? 172 LEU B CD1 1 
ATOM   6306  C  CD2 . LEU D 1 179 ? 143.407 112.173 150.108 1.00 59.71  ? 172 LEU B CD2 1 
ATOM   6307  N  N   . ASP D 1 180 ? 142.899 108.381 146.262 1.00 60.15  ? 173 ASP B N   1 
ATOM   6308  C  CA  . ASP D 1 180 ? 142.245 107.350 145.471 1.00 60.15  ? 173 ASP B CA  1 
ATOM   6309  C  C   . ASP D 1 180 ? 142.576 107.595 144.007 1.00 60.15  ? 173 ASP B C   1 
ATOM   6310  O  O   . ASP D 1 180 ? 142.608 108.743 143.554 1.00 60.15  ? 173 ASP B O   1 
ATOM   6311  C  CB  . ASP D 1 180 ? 140.726 107.354 145.727 1.00 60.15  ? 173 ASP B CB  1 
ATOM   6312  C  CG  . ASP D 1 180 ? 139.937 106.457 144.771 1.00 60.15  ? 173 ASP B CG  1 
ATOM   6313  O  OD1 . ASP D 1 180 ? 140.238 106.379 143.565 1.00 60.15  ? 173 ASP B OD1 1 
ATOM   6314  O  OD2 . ASP D 1 180 ? 138.984 105.807 145.250 1.00 60.15  ? 173 ASP B OD2 1 
ATOM   6315  N  N   . SER D 1 181 ? 142.787 106.501 143.269 1.00 59.94  ? 174 SER B N   1 
ATOM   6316  C  CA  . SER D 1 181 ? 143.208 106.605 141.876 1.00 59.94  ? 174 SER B CA  1 
ATOM   6317  C  C   . SER D 1 181 ? 142.171 107.315 141.017 1.00 59.94  ? 174 SER B C   1 
ATOM   6318  O  O   . SER D 1 181 ? 142.531 107.964 140.029 1.00 59.94  ? 174 SER B O   1 
ATOM   6319  C  CB  . SER D 1 181 ? 143.498 105.213 141.312 1.00 59.94  ? 174 SER B CB  1 
ATOM   6320  O  OG  . SER D 1 181 ? 144.428 104.520 142.124 1.00 59.94  ? 174 SER B OG  1 
ATOM   6321  N  N   . GLU D 1 182 ? 140.887 107.199 141.364 1.00 57.77  ? 175 GLU B N   1 
ATOM   6322  C  CA  . GLU D 1 182 ? 139.860 107.925 140.623 1.00 57.77  ? 175 GLU B CA  1 
ATOM   6323  C  C   . GLU D 1 182 ? 140.090 109.429 140.669 1.00 57.77  ? 175 GLU B C   1 
ATOM   6324  O  O   . GLU D 1 182 ? 139.814 110.124 139.683 1.00 57.77  ? 175 GLU B O   1 
ATOM   6325  C  CB  . GLU D 1 182 ? 138.471 107.576 141.162 1.00 57.77  ? 175 GLU B CB  1 
ATOM   6326  C  CG  . GLU D 1 182 ? 137.785 106.390 140.477 1.00 57.77  ? 175 GLU B CG  1 
ATOM   6327  C  CD  . GLU D 1 182 ? 138.470 105.048 140.700 1.00 57.77  ? 175 GLU B CD  1 
ATOM   6328  O  OE1 . GLU D 1 182 ? 139.507 104.988 141.392 1.00 57.77  ? 175 GLU B OE1 1 
ATOM   6329  O  OE2 . GLU D 1 182 ? 137.960 104.036 140.174 1.00 57.77  ? 175 GLU B OE2 1 
ATOM   6330  N  N   . ASP D 1 183 ? 140.611 109.948 141.786 1.00 54.38  ? 176 ASP B N   1 
ATOM   6331  C  CA  . ASP D 1 183 ? 140.936 111.370 141.858 1.00 54.38  ? 176 ASP B CA  1 
ATOM   6332  C  C   . ASP D 1 183 ? 141.892 111.774 140.747 1.00 54.38  ? 176 ASP B C   1 
ATOM   6333  O  O   . ASP D 1 183 ? 141.837 112.909 140.260 1.00 54.38  ? 176 ASP B O   1 
ATOM   6334  C  CB  . ASP D 1 183 ? 141.542 111.707 143.217 1.00 54.38  ? 176 ASP B CB  1 
ATOM   6335  C  CG  . ASP D 1 183 ? 141.449 113.181 143.545 1.00 54.38  ? 176 ASP B CG  1 
ATOM   6336  O  OD1 . ASP D 1 183 ? 140.813 113.924 142.771 1.00 54.38  ? 176 ASP B OD1 1 
ATOM   6337  O  OD2 . ASP D 1 183 ? 142.019 113.600 144.574 1.00 54.38  ? 176 ASP B OD2 1 
ATOM   6338  N  N   . LEU D 1 184 ? 142.741 110.845 140.309 1.00 49.77  ? 177 LEU B N   1 
ATOM   6339  C  CA  . LEU D 1 184 ? 143.704 111.135 139.259 1.00 49.77  ? 177 LEU B CA  1 
ATOM   6340  C  C   . LEU D 1 184 ? 143.029 111.580 137.971 1.00 49.77  ? 177 LEU B C   1 
ATOM   6341  O  O   . LEU D 1 184 ? 143.672 112.224 137.137 1.00 49.77  ? 177 LEU B O   1 
ATOM   6342  C  CB  . LEU D 1 184 ? 144.560 109.897 138.998 1.00 49.77  ? 177 LEU B CB  1 
ATOM   6343  C  CG  . LEU D 1 184 ? 145.847 109.793 139.815 1.00 49.77  ? 177 LEU B CG  1 
ATOM   6344  C  CD1 . LEU D 1 184 ? 146.188 108.336 140.086 1.00 49.77  ? 177 LEU B CD1 1 
ATOM   6345  C  CD2 . LEU D 1 184 ? 146.991 110.491 139.116 1.00 49.77  ? 177 LEU B CD2 1 
ATOM   6346  N  N   . GLN D 1 185 ? 141.749 111.259 137.789 1.00 47.40  ? 178 GLN B N   1 
ATOM   6347  C  CA  . GLN D 1 185 ? 141.050 111.659 136.576 1.00 47.40  ? 178 GLN B CA  1 
ATOM   6348  C  C   . GLN D 1 185 ? 140.666 113.133 136.559 1.00 47.40  ? 178 GLN B C   1 
ATOM   6349  O  O   . GLN D 1 185 ? 140.311 113.644 135.493 1.00 47.40  ? 178 GLN B O   1 
ATOM   6350  C  CB  . GLN D 1 185 ? 139.795 110.807 136.381 1.00 47.40  ? 178 GLN B CB  1 
ATOM   6351  C  CG  . GLN D 1 185 ? 140.068 109.391 135.909 1.00 47.40  ? 178 GLN B CG  1 
ATOM   6352  C  CD  . GLN D 1 185 ? 138.803 108.568 135.793 1.00 47.40  ? 178 GLN B CD  1 
ATOM   6353  O  OE1 . GLN D 1 185 ? 137.696 109.099 135.880 1.00 47.40  ? 178 GLN B OE1 1 
ATOM   6354  N  NE2 . GLN D 1 185 ? 138.959 107.266 135.594 1.00 47.40  ? 178 GLN B NE2 1 
ATOM   6355  N  N   . ASP D 1 186 ? 140.727 113.827 137.694 1.00 46.02  ? 179 ASP B N   1 
ATOM   6356  C  CA  . ASP D 1 186 ? 140.365 115.238 137.743 1.00 46.02  ? 179 ASP B CA  1 
ATOM   6357  C  C   . ASP D 1 186 ? 141.567 116.160 137.608 1.00 46.02  ? 179 ASP B C   1 
ATOM   6358  O  O   . ASP D 1 186 ? 141.446 117.358 137.876 1.00 46.02  ? 179 ASP B O   1 
ATOM   6359  C  CB  . ASP D 1 186 ? 139.624 115.555 139.044 1.00 46.02  ? 179 ASP B CB  1 
ATOM   6360  C  CG  . ASP D 1 186 ? 138.404 114.686 139.245 1.00 46.02  ? 179 ASP B CG  1 
ATOM   6361  O  OD1 . ASP D 1 186 ? 137.604 114.551 138.299 1.00 46.02  ? 179 ASP B OD1 1 
ATOM   6362  O  OD2 . ASP D 1 186 ? 138.244 114.140 140.354 1.00 46.02  ? 179 ASP B OD2 1 
ATOM   6363  N  N   . MET D 1 187 ? 142.714 115.633 137.200 1.00 46.06  ? 180 MET B N   1 
ATOM   6364  C  CA  . MET D 1 187 ? 143.959 116.382 137.160 1.00 46.06  ? 180 MET B CA  1 
ATOM   6365  C  C   . MET D 1 187 ? 144.327 116.712 135.717 1.00 46.06  ? 180 MET B C   1 
ATOM   6366  O  O   . MET D 1 187 ? 143.564 116.470 134.781 1.00 46.06  ? 180 MET B O   1 
ATOM   6367  C  CB  . MET D 1 187 ? 145.070 115.573 137.831 1.00 46.06  ? 180 MET B CB  1 
ATOM   6368  C  CG  . MET D 1 187 ? 144.757 115.218 139.273 1.00 46.06  ? 180 MET B CG  1 
ATOM   6369  S  SD  . MET D 1 187 ? 146.206 114.934 140.298 1.00 46.06  ? 180 MET B SD  1 
ATOM   6370  C  CE  . MET D 1 187 ? 145.608 115.513 141.878 1.00 46.06  ? 180 MET B CE  1 
ATOM   6371  N  N   . SER D 1 188 ? 145.513 117.287 135.546 1.00 41.37  ? 181 SER B N   1 
ATOM   6372  C  CA  . SER D 1 188 ? 146.080 117.526 134.226 1.00 41.37  ? 181 SER B CA  1 
ATOM   6373  C  C   . SER D 1 188 ? 147.455 116.881 134.139 1.00 41.37  ? 181 SER B C   1 
ATOM   6374  O  O   . SER D 1 188 ? 148.252 116.973 135.076 1.00 41.37  ? 181 SER B O   1 
ATOM   6375  C  CB  . SER D 1 188 ? 146.180 119.021 133.925 1.00 41.37  ? 181 SER B CB  1 
ATOM   6376  O  OG  . SER D 1 188 ? 144.910 119.557 133.599 1.00 41.37  ? 181 SER B OG  1 
ATOM   6377  N  N   . LEU D 1 189 ? 147.726 116.228 133.016 1.00 40.42  ? 182 LEU B N   1 
ATOM   6378  C  CA  . LEU D 1 189 ? 148.984 115.523 132.834 1.00 40.42  ? 182 LEU B CA  1 
ATOM   6379  C  C   . LEU D 1 189 ? 150.053 116.454 132.283 1.00 40.42  ? 182 LEU B C   1 
ATOM   6380  O  O   . LEU D 1 189 ? 149.764 117.413 131.566 1.00 40.42  ? 182 LEU B O   1 
ATOM   6381  C  CB  . LEU D 1 189 ? 148.809 114.330 131.895 1.00 40.42  ? 182 LEU B CB  1 
ATOM   6382  C  CG  . LEU D 1 189 ? 148.070 113.122 132.469 1.00 40.42  ? 182 LEU B CG  1 
ATOM   6383  C  CD1 . LEU D 1 189 ? 146.612 113.131 132.041 1.00 40.42  ? 182 LEU B CD1 1 
ATOM   6384  C  CD2 . LEU D 1 189 ? 148.752 111.830 132.049 1.00 40.42  ? 182 LEU B CD2 1 
ATOM   6385  N  N   . MET D 1 190 ? 151.305 116.142 132.647 1.00 43.23  ? 183 MET B N   1 
ATOM   6386  C  CA  . MET D 1 190 ? 152.479 116.909 132.154 1.00 43.23  ? 183 MET B CA  1 
ATOM   6387  C  C   . MET D 1 190 ? 153.627 115.907 131.993 1.00 43.23  ? 183 MET B C   1 
ATOM   6388  O  O   . MET D 1 190 ? 153.888 115.160 132.958 1.00 43.23  ? 183 MET B O   1 
ATOM   6389  C  CB  . MET D 1 190 ? 152.886 118.007 133.143 1.00 43.23  ? 183 MET B CB  1 
ATOM   6390  C  CG  . MET D 1 190 ? 154.379 118.284 133.158 1.00 43.23  ? 183 MET B CG  1 
ATOM   6391  S  SD  . MET D 1 190 ? 154.816 119.675 134.228 1.00 43.23  ? 183 MET B SD  1 
ATOM   6392  C  CE  . MET D 1 190 ? 153.431 120.767 133.913 1.00 43.23  ? 183 MET B CE  1 
ATOM   6393  N  N   . THR D 1 191 ? 154.274 115.874 130.826 1.00 43.92  ? 184 THR B N   1 
ATOM   6394  C  CA  . THR D 1 191 ? 155.328 114.913 130.546 1.00 43.92  ? 184 THR B CA  1 
ATOM   6395  C  C   . THR D 1 191 ? 156.661 115.636 130.449 1.00 43.92  ? 184 THR B C   1 
ATOM   6396  O  O   . THR D 1 191 ? 156.791 116.607 129.699 1.00 43.92  ? 184 THR B O   1 
ATOM   6397  C  CB  . THR D 1 191 ? 155.046 114.147 129.250 1.00 43.92  ? 184 THR B CB  1 
ATOM   6398  O  OG1 . THR D 1 191 ? 153.965 113.230 129.461 1.00 43.92  ? 184 THR B OG1 1 
ATOM   6399  C  CG2 . THR D 1 191 ? 156.275 113.372 128.807 1.00 43.92  ? 184 THR B CG2 1 
ATOM   6400  N  N   . LEU D 1 192 ? 157.645 115.163 131.206 1.00 44.53  ? 185 LEU B N   1 
ATOM   6401  C  CA  . LEU D 1 192 ? 159.017 115.644 131.101 1.00 44.53  ? 185 LEU B CA  1 
ATOM   6402  C  C   . LEU D 1 192 ? 159.834 114.555 130.421 1.00 44.53  ? 185 LEU B C   1 
ATOM   6403  O  O   . LEU D 1 192 ? 160.105 113.511 131.022 1.00 44.53  ? 185 LEU B O   1 
ATOM   6404  C  CB  . LEU D 1 192 ? 159.591 115.990 132.472 1.00 44.53  ? 185 LEU B CB  1 
ATOM   6405  C  CG  . LEU D 1 192 ? 161.103 116.227 132.511 1.00 44.53  ? 185 LEU B CG  1 
ATOM   6406  C  CD1 . LEU D 1 192 ? 161.448 117.588 131.941 1.00 44.53  ? 185 LEU B CD1 1 
ATOM   6407  C  CD2 . LEU D 1 192 ? 161.635 116.093 133.923 1.00 44.53  ? 185 LEU B CD2 1 
ATOM   6408  N  N   . SER D 1 193 ? 160.207 114.788 129.167 1.00 49.25  ? 186 SER B N   1 
ATOM   6409  C  CA  . SER D 1 193 ? 161.000 113.842 128.397 1.00 49.25  ? 186 SER B CA  1 
ATOM   6410  C  C   . SER D 1 193 ? 162.454 114.287 128.428 1.00 49.25  ? 186 SER B C   1 
ATOM   6411  O  O   . SER D 1 193 ? 162.770 115.416 128.032 1.00 49.25  ? 186 SER B O   1 
ATOM   6412  C  CB  . SER D 1 193 ? 160.497 113.753 126.958 1.00 49.25  ? 186 SER B CB  1 
ATOM   6413  O  OG  . SER D 1 193 ? 159.204 113.178 126.908 1.00 49.25  ? 186 SER B OG  1 
ATOM   6414  N  N   . THR D 1 194 ? 163.333 113.405 128.902 1.00 54.56  ? 187 THR B N   1 
ATOM   6415  C  CA  . THR D 1 194 ? 164.756 113.687 129.001 1.00 54.56  ? 187 THR B CA  1 
ATOM   6416  C  C   . THR D 1 194 ? 165.525 112.657 128.191 1.00 54.56  ? 187 THR B C   1 
ATOM   6417  O  O   . THR D 1 194 ? 165.271 111.453 128.303 1.00 54.56  ? 187 THR B O   1 
ATOM   6418  C  CB  . THR D 1 194 ? 165.223 113.663 130.456 1.00 54.56  ? 187 THR B CB  1 
ATOM   6419  O  OG1 . THR D 1 194 ? 164.885 112.403 131.045 1.00 54.56  ? 187 THR B OG1 1 
ATOM   6420  C  CG2 . THR D 1 194 ? 164.554 114.775 131.243 1.00 54.56  ? 187 THR B CG2 1 
ATOM   6421  N  N   . LYS D 1 195 ? 166.457 113.133 127.372 1.00 57.89  ? 188 LYS B N   1 
ATOM   6422  C  CA  . LYS D 1 195 ? 167.319 112.262 126.574 1.00 57.89  ? 188 LYS B CA  1 
ATOM   6423  C  C   . LYS D 1 195 ? 168.722 112.852 126.647 1.00 57.89  ? 188 LYS B C   1 
ATOM   6424  O  O   . LYS D 1 195 ? 169.028 113.829 125.959 1.00 57.89  ? 188 LYS B O   1 
ATOM   6425  C  CB  . LYS D 1 195 ? 166.825 112.149 125.138 1.00 57.89  ? 188 LYS B CB  1 
ATOM   6426  C  CG  . LYS D 1 195 ? 167.570 111.128 124.303 1.00 57.89  ? 188 LYS B CG  1 
ATOM   6427  C  CD  . LYS D 1 195 ? 166.722 110.661 123.133 1.00 57.89  ? 188 LYS B CD  1 
ATOM   6428  C  CE  . LYS D 1 195 ? 167.508 109.751 122.206 1.00 57.89  ? 188 LYS B CE  1 
ATOM   6429  N  NZ  . LYS D 1 195 ? 168.288 108.730 122.956 1.00 57.89  ? 188 LYS B NZ  1 
ATOM   6430  N  N   . THR D 1 196 ? 169.550 112.282 127.512 1.00 62.47  ? 189 THR B N   1 
ATOM   6431  C  CA  . THR D 1 196 ? 170.884 112.781 127.801 1.00 62.47  ? 189 THR B CA  1 
ATOM   6432  C  C   . THR D 1 196 ? 171.845 111.606 127.866 1.00 62.47  ? 189 THR B C   1 
ATOM   6433  O  O   . THR D 1 196 ? 171.416 110.454 127.993 1.00 62.47  ? 189 THR B O   1 
ATOM   6434  C  CB  . THR D 1 196 ? 170.937 113.556 129.126 1.00 62.47  ? 189 THR B CB  1 
ATOM   6435  O  OG1 . THR D 1 196 ? 171.209 112.646 130.200 1.00 62.47  ? 189 THR B OG1 1 
ATOM   6436  C  CG2 . THR D 1 196 ? 169.627 114.279 129.401 1.00 62.47  ? 189 THR B CG2 1 
ATOM   6437  N  N   . PRO D 1 197 ? 173.149 111.859 127.765 1.00 65.91  ? 190 PRO B N   1 
ATOM   6438  C  CA  . PRO D 1 197 ? 174.129 110.786 127.981 1.00 65.91  ? 190 PRO B CA  1 
ATOM   6439  C  C   . PRO D 1 197 ? 174.032 110.203 129.384 1.00 65.91  ? 190 PRO B C   1 
ATOM   6440  O  O   . PRO D 1 197 ? 173.329 110.705 130.263 1.00 65.91  ? 190 PRO B O   1 
ATOM   6441  C  CB  . PRO D 1 197 ? 175.472 111.483 127.752 1.00 65.91  ? 190 PRO B CB  1 
ATOM   6442  C  CG  . PRO D 1 197 ? 175.152 112.597 126.826 1.00 65.91  ? 190 PRO B CG  1 
ATOM   6443  C  CD  . PRO D 1 197 ? 173.781 113.071 127.214 1.00 65.91  ? 190 PRO B CD  1 
ATOM   6444  N  N   . LYS D 1 198 ? 174.767 109.105 129.586 1.00 66.56  ? 191 LYS B N   1 
ATOM   6445  C  CA  . LYS D 1 198 ? 174.670 108.355 130.835 1.00 66.56  ? 191 LYS B CA  1 
ATOM   6446  C  C   . LYS D 1 198 ? 175.195 109.156 132.021 1.00 66.56  ? 191 LYS B C   1 
ATOM   6447  O  O   . LYS D 1 198 ? 174.567 109.182 133.085 1.00 66.56  ? 191 LYS B O   1 
ATOM   6448  C  CB  . LYS D 1 198 ? 175.431 107.032 130.711 1.00 66.56  ? 191 LYS B CB  1 
ATOM   6449  C  CG  . LYS D 1 198 ? 175.174 106.250 129.418 1.00 66.56  ? 191 LYS B CG  1 
ATOM   6450  C  CD  . LYS D 1 198 ? 173.704 105.887 129.173 1.00 66.56  ? 191 LYS B CD  1 
ATOM   6451  C  CE  . LYS D 1 198 ? 172.965 105.468 130.444 1.00 66.56  ? 191 LYS B CE  1 
ATOM   6452  N  NZ  . LYS D 1 198 ? 173.625 104.317 131.120 1.00 66.56  ? 191 LYS B NZ  1 
ATOM   6453  N  N   . ASP D 1 199 ? 176.343 109.813 131.860 1.00 66.75  ? 192 ASP B N   1 
ATOM   6454  C  CA  . ASP D 1 199 ? 176.986 110.550 132.940 1.00 66.75  ? 192 ASP B CA  1 
ATOM   6455  C  C   . ASP D 1 199 ? 176.641 112.038 132.936 1.00 66.75  ? 192 ASP B C   1 
ATOM   6456  O  O   . ASP D 1 199 ? 177.325 112.827 133.597 1.00 66.75  ? 192 ASP B O   1 
ATOM   6457  C  CB  . ASP D 1 199 ? 178.503 110.294 132.905 1.00 66.75  ? 192 ASP B CB  1 
ATOM   6458  C  CG  . ASP D 1 199 ? 179.290 111.246 131.981 1.00 66.75  ? 192 ASP B CG  1 
ATOM   6459  O  OD1 . ASP D 1 199 ? 180.513 111.026 131.848 1.00 66.75  ? 192 ASP B OD1 1 
ATOM   6460  O  OD2 . ASP D 1 199 ? 178.729 112.148 131.326 1.00 66.75  ? 192 ASP B OD2 1 
ATOM   6461  N  N   . PHE D 1 200 ? 175.582 112.428 132.225 1.00 60.86  ? 193 PHE B N   1 
ATOM   6462  C  CA  . PHE D 1 200 ? 175.258 113.844 132.084 1.00 60.86  ? 193 PHE B CA  1 
ATOM   6463  C  C   . PHE D 1 200 ? 174.912 114.482 133.423 1.00 60.86  ? 193 PHE B C   1 
ATOM   6464  O  O   . PHE D 1 200 ? 175.462 115.529 133.781 1.00 60.86  ? 193 PHE B O   1 
ATOM   6465  C  CB  . PHE D 1 200 ? 174.105 114.021 131.098 1.00 60.86  ? 193 PHE B CB  1 
ATOM   6466  C  CG  . PHE D 1 200 ? 173.682 115.449 130.916 1.00 60.86  ? 193 PHE B CG  1 
ATOM   6467  C  CD1 . PHE D 1 200 ? 174.516 116.358 130.294 1.00 60.86  ? 193 PHE B CD1 1 
ATOM   6468  C  CD2 . PHE D 1 200 ? 172.447 115.880 131.367 1.00 60.86  ? 193 PHE B CD2 1 
ATOM   6469  C  CE1 . PHE D 1 200 ? 174.128 117.670 130.127 1.00 60.86  ? 193 PHE B CE1 1 
ATOM   6470  C  CE2 . PHE D 1 200 ? 172.053 117.190 131.200 1.00 60.86  ? 193 PHE B CE2 1 
ATOM   6471  C  CZ  . PHE D 1 200 ? 172.894 118.087 130.581 1.00 60.86  ? 193 PHE B CZ  1 
ATOM   6472  N  N   . PHE D 1 201 ? 174.013 113.863 134.183 1.00 57.07  ? 194 PHE B N   1 
ATOM   6473  C  CA  . PHE D 1 201 ? 173.451 114.513 135.360 1.00 57.07  ? 194 PHE B CA  1 
ATOM   6474  C  C   . PHE D 1 201 ? 174.359 114.447 136.578 1.00 57.07  ? 194 PHE B C   1 
ATOM   6475  O  O   . PHE D 1 201 ? 173.939 114.850 137.668 1.00 57.07  ? 194 PHE B O   1 
ATOM   6476  C  CB  . PHE D 1 201 ? 172.082 113.915 135.683 1.00 57.07  ? 194 PHE B CB  1 
ATOM   6477  C  CG  . PHE D 1 201 ? 170.978 114.497 134.858 1.00 57.07  ? 194 PHE B CG  1 
ATOM   6478  C  CD1 . PHE D 1 201 ? 170.371 115.679 135.229 1.00 57.07  ? 194 PHE B CD1 1 
ATOM   6479  C  CD2 . PHE D 1 201 ? 170.564 113.873 133.696 1.00 57.07  ? 194 PHE B CD2 1 
ATOM   6480  C  CE1 . PHE D 1 201 ? 169.367 116.223 134.462 1.00 57.07  ? 194 PHE B CE1 1 
ATOM   6481  C  CE2 . PHE D 1 201 ? 169.556 114.411 132.929 1.00 57.07  ? 194 PHE B CE2 1 
ATOM   6482  C  CZ  . PHE D 1 201 ? 168.958 115.586 133.311 1.00 57.07  ? 194 PHE B CZ  1 
ATOM   6483  N  N   . THR D 1 202 ? 175.588 113.955 136.425 1.00 62.60  ? 195 THR B N   1 
ATOM   6484  C  CA  . THR D 1 202 ? 176.571 114.097 137.490 1.00 62.60  ? 195 THR B CA  1 
ATOM   6485  C  C   . THR D 1 202 ? 177.064 115.534 137.608 1.00 62.60  ? 195 THR B C   1 
ATOM   6486  O  O   . THR D 1 202 ? 177.535 115.932 138.679 1.00 62.60  ? 195 THR B O   1 
ATOM   6487  C  CB  . THR D 1 202 ? 177.748 113.148 137.248 1.00 62.60  ? 195 THR B CB  1 
ATOM   6488  O  OG1 . THR D 1 202 ? 177.252 111.861 136.863 1.00 62.60  ? 195 THR B OG1 1 
ATOM   6489  C  CG2 . THR D 1 202 ? 178.584 112.993 138.509 1.00 62.60  ? 195 THR B CG2 1 
ATOM   6490  N  N   . ASN D 1 203 ? 176.948 116.326 136.538 1.00 59.89  ? 196 ASN B N   1 
ATOM   6491  C  CA  . ASN D 1 203 ? 177.400 117.713 136.542 1.00 59.89  ? 196 ASN B CA  1 
ATOM   6492  C  C   . ASN D 1 203 ? 176.298 118.681 136.123 1.00 59.89  ? 196 ASN B C   1 
ATOM   6493  O  O   . ASN D 1 203 ? 176.599 119.777 135.641 1.00 59.89  ? 196 ASN B O   1 
ATOM   6494  C  CB  . ASN D 1 203 ? 178.619 117.885 135.633 1.00 59.89  ? 196 ASN B CB  1 
ATOM   6495  C  CG  . ASN D 1 203 ? 179.807 117.069 136.096 1.00 59.89  ? 196 ASN B CG  1 
ATOM   6496  O  OD1 . ASN D 1 203 ? 180.247 117.185 137.240 1.00 59.89  ? 196 ASN B OD1 1 
ATOM   6497  N  ND2 . ASN D 1 203 ? 180.338 116.238 135.207 1.00 59.89  ? 196 ASN B ND2 1 
ATOM   6498  N  N   . HIS D 1 204 ? 175.033 118.303 136.292 1.00 52.86  ? 197 HIS B N   1 
ATOM   6499  C  CA  . HIS D 1 204 ? 173.914 119.172 135.959 1.00 52.86  ? 197 HIS B CA  1 
ATOM   6500  C  C   . HIS D 1 204 ? 172.727 118.798 136.833 1.00 52.86  ? 197 HIS B C   1 
ATOM   6501  O  O   . HIS D 1 204 ? 172.657 117.694 137.377 1.00 52.86  ? 197 HIS B O   1 
ATOM   6502  C  CB  . HIS D 1 204 ? 173.545 119.077 134.475 1.00 52.86  ? 197 HIS B CB  1 
ATOM   6503  C  CG  . HIS D 1 204 ? 174.501 119.787 133.568 1.00 52.86  ? 197 HIS B CG  1 
ATOM   6504  N  ND1 . HIS D 1 204 ? 175.383 119.120 132.747 1.00 52.86  ? 197 HIS B ND1 1 
ATOM   6505  C  CD2 . HIS D 1 204 ? 174.714 121.107 133.355 1.00 52.86  ? 197 HIS B CD2 1 
ATOM   6506  C  CE1 . HIS D 1 204 ? 176.098 119.997 132.066 1.00 52.86  ? 197 HIS B CE1 1 
ATOM   6507  N  NE2 . HIS D 1 204 ? 175.711 121.211 132.417 1.00 52.86  ? 197 HIS B NE2 1 
ATOM   6508  N  N   . THR D 1 205 ? 171.791 119.734 136.965 1.00 44.47  ? 198 THR B N   1 
ATOM   6509  C  CA  . THR D 1 205 ? 170.632 119.556 137.827 1.00 44.47  ? 198 THR B CA  1 
ATOM   6510  C  C   . THR D 1 205 ? 169.399 120.116 137.134 1.00 44.47  ? 198 THR B C   1 
ATOM   6511  O  O   . THR D 1 205 ? 169.489 121.064 136.354 1.00 44.47  ? 198 THR B O   1 
ATOM   6512  C  CB  . THR D 1 205 ? 170.866 120.241 139.193 1.00 44.47  ? 198 THR B CB  1 
ATOM   6513  O  OG1 . THR D 1 205 ? 171.748 119.437 139.984 1.00 44.47  ? 198 THR B OG1 1 
ATOM   6514  C  CG2 . THR D 1 205 ? 169.570 120.441 139.960 1.00 44.47  ? 198 THR B CG2 1 
ATOM   6515  N  N   . LEU D 1 206 ? 168.245 119.510 137.404 1.00 38.84  ? 199 LEU B N   1 
ATOM   6516  C  CA  . LEU D 1 206 ? 166.973 119.979 136.877 1.00 38.84  ? 199 LEU B CA  1 
ATOM   6517  C  C   . LEU D 1 206 ? 166.132 120.504 138.033 1.00 38.84  ? 199 LEU B C   1 
ATOM   6518  O  O   . LEU D 1 206 ? 166.190 119.965 139.143 1.00 38.84  ? 199 LEU B O   1 
ATOM   6519  C  CB  . LEU D 1 206 ? 166.226 118.858 136.153 1.00 38.84  ? 199 LEU B CB  1 
ATOM   6520  C  CG  . LEU D 1 206 ? 166.535 118.673 134.664 1.00 38.84  ? 199 LEU B CG  1 
ATOM   6521  C  CD1 . LEU D 1 206 ? 166.058 117.311 134.186 1.00 38.84  ? 199 LEU B CD1 1 
ATOM   6522  C  CD2 . LEU D 1 206 ? 165.963 119.782 133.810 1.00 38.84  ? 199 LEU B CD2 1 
ATOM   6523  N  N   . VAL D 1 207 ? 165.368 121.565 137.785 1.00 33.92  ? 200 VAL B N   1 
ATOM   6524  C  CA  . VAL D 1 207 ? 164.522 122.183 138.800 1.00 33.92  ? 200 VAL B CA  1 
ATOM   6525  C  C   . VAL D 1 207 ? 163.149 122.443 138.204 1.00 33.92  ? 200 VAL B C   1 
ATOM   6526  O  O   . VAL D 1 207 ? 163.035 122.839 137.040 1.00 33.92  ? 200 VAL B O   1 
ATOM   6527  C  CB  . VAL D 1 207 ? 165.125 123.502 139.328 1.00 33.92  ? 200 VAL B CB  1 
ATOM   6528  C  CG1 . VAL D 1 207 ? 164.303 124.034 140.486 1.00 33.92  ? 200 VAL B CG1 1 
ATOM   6529  C  CG2 . VAL D 1 207 ? 166.557 123.300 139.746 1.00 33.92  ? 200 VAL B CG2 1 
ATOM   6530  N  N   . LEU D 1 208 ? 162.108 122.229 139.000 1.00 30.47  ? 201 LEU B N   1 
ATOM   6531  C  CA  . LEU D 1 208 ? 160.751 122.591 138.626 1.00 30.47  ? 201 LEU B CA  1 
ATOM   6532  C  C   . LEU D 1 208 ? 160.270 123.663 139.587 1.00 30.47  ? 201 LEU B C   1 
ATOM   6533  O  O   . LEU D 1 208 ? 160.537 123.584 140.791 1.00 30.47  ? 201 LEU B O   1 
ATOM   6534  C  CB  . LEU D 1 208 ? 159.821 121.378 138.673 1.00 30.47  ? 201 LEU B CB  1 
ATOM   6535  C  CG  . LEU D 1 208 ? 158.457 121.526 138.008 1.00 30.47  ? 201 LEU B CG  1 
ATOM   6536  C  CD1 . LEU D 1 208 ? 158.597 121.414 136.505 1.00 30.47  ? 201 LEU B CD1 1 
ATOM   6537  C  CD2 . LEU D 1 208 ? 157.497 120.481 138.534 1.00 30.47  ? 201 LEU B CD2 1 
ATOM   6538  N  N   . HIS D 1 209 ? 159.582 124.677 139.069 1.00 28.76  ? 202 HIS B N   1 
ATOM   6539  C  CA  . HIS D 1 209 ? 159.151 125.749 139.958 1.00 28.76  ? 202 HIS B CA  1 
ATOM   6540  C  C   . HIS D 1 209 ? 157.951 126.485 139.379 1.00 28.76  ? 202 HIS B C   1 
ATOM   6541  O  O   . HIS D 1 209 ? 157.575 126.312 138.217 1.00 28.76  ? 202 HIS B O   1 
ATOM   6542  C  CB  . HIS D 1 209 ? 160.299 126.720 140.257 1.00 28.76  ? 202 HIS B CB  1 
ATOM   6543  C  CG  . HIS D 1 209 ? 160.805 127.463 139.061 1.00 28.76  ? 202 HIS B CG  1 
ATOM   6544  N  ND1 . HIS D 1 209 ? 161.956 127.103 138.395 1.00 28.76  ? 202 HIS B ND1 1 
ATOM   6545  C  CD2 . HIS D 1 209 ? 160.337 128.566 138.433 1.00 28.76  ? 202 HIS B CD2 1 
ATOM   6546  C  CE1 . HIS D 1 209 ? 162.164 127.941 137.396 1.00 28.76  ? 202 HIS B CE1 1 
ATOM   6547  N  NE2 . HIS D 1 209 ? 161.198 128.840 137.400 1.00 28.76  ? 202 HIS B NE2 1 
ATOM   6548  N  N   . VAL D 1 210 ? 157.337 127.292 140.242 1.00 29.58  ? 203 VAL B N   1 
ATOM   6549  C  CA  . VAL D 1 210 ? 156.229 128.173 139.905 1.00 29.58  ? 203 VAL B CA  1 
ATOM   6550  C  C   . VAL D 1 210 ? 156.457 129.488 140.637 1.00 29.58  ? 203 VAL B C   1 
ATOM   6551  O  O   . VAL D 1 210 ? 157.019 129.515 141.736 1.00 29.58  ? 203 VAL B O   1 
ATOM   6552  C  CB  . VAL D 1 210 ? 154.868 127.544 140.281 1.00 29.58  ? 203 VAL B CB  1 
ATOM   6553  C  CG1 . VAL D 1 210 ? 154.794 127.299 141.773 1.00 29.58  ? 203 VAL B CG1 1 
ATOM   6554  C  CG2 . VAL D 1 210 ? 153.719 128.427 139.837 1.00 29.58  ? 203 VAL B CG2 1 
ATOM   6555  N  N   . ALA D 1 211 ? 156.037 130.589 140.017 1.00 33.15  ? 204 ALA B N   1 
ATOM   6556  C  CA  . ALA D 1 211 ? 156.267 131.904 140.600 1.00 33.15  ? 204 ALA B CA  1 
ATOM   6557  C  C   . ALA D 1 211 ? 155.584 132.019 141.957 1.00 33.15  ? 204 ALA B C   1 
ATOM   6558  O  O   . ALA D 1 211 ? 154.538 131.416 142.201 1.00 33.15  ? 204 ALA B O   1 
ATOM   6559  C  CB  . ALA D 1 211 ? 155.760 132.998 139.662 1.00 33.15  ? 204 ALA B CB  1 
ATOM   6560  N  N   . ARG D 1 212 ? 156.192 132.807 142.850 1.00 30.95  ? 205 ARG B N   1 
ATOM   6561  C  CA  . ARG D 1 212 ? 155.715 132.895 144.226 1.00 30.95  ? 205 ARG B CA  1 
ATOM   6562  C  C   . ARG D 1 212 ? 154.301 133.450 144.332 1.00 30.95  ? 205 ARG B C   1 
ATOM   6563  O  O   . ARG D 1 212 ? 153.626 133.200 145.336 1.00 30.95  ? 205 ARG B O   1 
ATOM   6564  C  CB  . ARG D 1 212 ? 156.660 133.757 145.059 1.00 30.95  ? 205 ARG B CB  1 
ATOM   6565  C  CG  . ARG D 1 212 ? 157.930 133.054 145.486 1.00 30.95  ? 205 ARG B CG  1 
ATOM   6566  C  CD  . ARG D 1 212 ? 158.509 133.690 146.737 1.00 30.95  ? 205 ARG B CD  1 
ATOM   6567  N  NE  . ARG D 1 212 ? 159.571 132.879 147.319 1.00 30.95  ? 205 ARG B NE  1 
ATOM   6568  C  CZ  . ARG D 1 212 ? 159.470 132.235 148.473 1.00 30.95  ? 205 ARG B CZ  1 
ATOM   6569  N  NH1 . ARG D 1 212 ? 158.365 132.288 149.198 1.00 30.95  ? 205 ARG B NH1 1 
ATOM   6570  N  NH2 . ARG D 1 212 ? 160.503 131.519 148.909 1.00 30.95  ? 205 ARG B NH2 1 
ATOM   6571  N  N   . SER D 1 213 ? 153.838 134.205 143.335 1.00 32.56  ? 206 SER B N   1 
ATOM   6572  C  CA  . SER D 1 213 ? 152.482 134.734 143.388 1.00 32.56  ? 206 SER B CA  1 
ATOM   6573  C  C   . SER D 1 213 ? 151.444 133.703 142.974 1.00 32.56  ? 206 SER B C   1 
ATOM   6574  O  O   . SER D 1 213 ? 150.251 133.911 143.216 1.00 32.56  ? 206 SER B O   1 
ATOM   6575  C  CB  . SER D 1 213 ? 152.359 135.969 142.500 1.00 32.56  ? 206 SER B CB  1 
ATOM   6576  O  OG  . SER D 1 213 ? 151.028 136.130 142.045 1.00 32.56  ? 206 SER B OG  1 
ATOM   6577  N  N   . GLU D 1 214 ? 151.867 132.604 142.352 1.00 34.01  ? 207 GLU B N   1 
ATOM   6578  C  CA  . GLU D 1 214 ? 150.969 131.537 141.933 1.00 34.01  ? 207 GLU B CA  1 
ATOM   6579  C  C   . GLU D 1 214 ? 151.263 130.223 142.641 1.00 34.01  ? 207 GLU B C   1 
ATOM   6580  O  O   . GLU D 1 214 ? 150.579 129.227 142.393 1.00 34.01  ? 207 GLU B O   1 
ATOM   6581  C  CB  . GLU D 1 214 ? 151.048 131.348 140.417 1.00 34.01  ? 207 GLU B CB  1 
ATOM   6582  C  CG  . GLU D 1 214 ? 150.506 132.523 139.621 1.00 34.01  ? 207 GLU B CG  1 
ATOM   6583  C  CD  . GLU D 1 214 ? 151.425 132.938 138.488 1.00 34.01  ? 207 GLU B CD  1 
ATOM   6584  O  OE1 . GLU D 1 214 ? 152.500 132.324 138.335 1.00 34.01  ? 207 GLU B OE1 1 
ATOM   6585  O  OE2 . GLU D 1 214 ? 151.070 133.881 137.749 1.00 34.01  ? 207 GLU B OE2 1 
ATOM   6586  N  N   . MET D 1 215 ? 152.270 130.198 143.516 1.00 35.59  ? 208 MET B N   1 
ATOM   6587  C  CA  . MET D 1 215 ? 152.611 128.979 144.239 1.00 35.59  ? 208 MET B CA  1 
ATOM   6588  C  C   . MET D 1 215 ? 151.506 128.537 145.181 1.00 35.59  ? 208 MET B C   1 
ATOM   6589  O  O   . MET D 1 215 ? 151.481 127.371 145.584 1.00 35.59  ? 208 MET B O   1 
ATOM   6590  C  CB  . MET D 1 215 ? 153.910 129.185 145.020 1.00 35.59  ? 208 MET B CB  1 
ATOM   6591  C  CG  . MET D 1 215 ? 153.707 129.433 146.503 1.00 35.59  ? 208 MET B CG  1 
ATOM   6592  S  SD  . MET D 1 215 ? 155.242 129.394 147.437 1.00 35.59  ? 208 MET B SD  1 
ATOM   6593  C  CE  . MET D 1 215 ? 154.733 130.199 148.951 1.00 35.59  ? 208 MET B CE  1 
ATOM   6594  N  N   . ASP D 1 216 ? 150.592 129.435 145.541 1.00 36.33  ? 209 ASP B N   1 
ATOM   6595  C  CA  . ASP D 1 216 ? 149.511 129.119 146.460 1.00 36.33  ? 209 ASP B CA  1 
ATOM   6596  C  C   . ASP D 1 216 ? 148.189 128.844 145.748 1.00 36.33  ? 209 ASP B C   1 
ATOM   6597  O  O   . ASP D 1 216 ? 147.144 128.761 146.402 1.00 36.33  ? 209 ASP B O   1 
ATOM   6598  C  CB  . ASP D 1 216 ? 149.402 130.224 147.524 1.00 36.33  ? 209 ASP B CB  1 
ATOM   6599  C  CG  . ASP D 1 216 ? 148.675 131.486 147.045 1.00 36.33  ? 209 ASP B CG  1 
ATOM   6600  O  OD1 . ASP D 1 216 ? 149.148 132.583 147.410 1.00 36.33  ? 209 ASP B OD1 1 
ATOM   6601  O  OD2 . ASP D 1 216 ? 147.649 131.426 146.344 1.00 36.33  ? 209 ASP B OD2 1 
ATOM   6602  N  N   . LYS D 1 217 ? 148.219 128.669 144.422 1.00 33.44  ? 210 LYS B N   1 
ATOM   6603  C  CA  . LYS D 1 217 ? 147.024 128.342 143.651 1.00 33.44  ? 210 LYS B CA  1 
ATOM   6604  C  C   . LYS D 1 217 ? 147.235 127.133 142.746 1.00 33.44  ? 210 LYS B C   1 
ATOM   6605  O  O   . LYS D 1 217 ? 146.525 126.990 141.747 1.00 33.44  ? 210 LYS B O   1 
ATOM   6606  C  CB  . LYS D 1 217 ? 146.570 129.538 142.811 1.00 33.44  ? 210 LYS B CB  1 
ATOM   6607  C  CG  . LYS D 1 217 ? 146.278 130.797 143.602 1.00 33.44  ? 210 LYS B CG  1 
ATOM   6608  C  CD  . LYS D 1 217 ? 146.096 131.991 142.681 1.00 33.44  ? 210 LYS B CD  1 
ATOM   6609  C  CE  . LYS D 1 217 ? 145.836 133.266 143.465 1.00 33.44  ? 210 LYS B CE  1 
ATOM   6610  N  NZ  . LYS D 1 217 ? 147.057 133.756 144.158 1.00 33.44  ? 210 LYS B NZ  1 
ATOM   6611  N  N   . VAL D 1 218 ? 148.190 126.261 143.064 1.00 31.45  ? 211 VAL B N   1 
ATOM   6612  C  CA  . VAL D 1 218 ? 148.477 125.100 142.229 1.00 31.45  ? 211 VAL B CA  1 
ATOM   6613  C  C   . VAL D 1 218 ? 149.176 124.049 143.078 1.00 31.45  ? 211 VAL B C   1 
ATOM   6614  O  O   . VAL D 1 218 ? 149.827 124.366 144.077 1.00 31.45  ? 211 VAL B O   1 
ATOM   6615  C  CB  . VAL D 1 218 ? 149.332 125.488 140.999 1.00 31.45  ? 211 VAL B CB  1 
ATOM   6616  C  CG1 . VAL D 1 218 ? 150.784 125.683 141.390 1.00 31.45  ? 211 VAL B CG1 1 
ATOM   6617  C  CG2 . VAL D 1 218 ? 149.204 124.448 139.908 1.00 31.45  ? 211 VAL B CG2 1 
ATOM   6618  N  N   . ARG D 1 219 ? 149.019 122.785 142.689 1.00 39.79  ? 212 ARG B N   1 
ATOM   6619  C  CA  . ARG D 1 219 ? 149.741 121.690 143.320 1.00 39.79  ? 212 ARG B CA  1 
ATOM   6620  C  C   . ARG D 1 219 ? 150.114 120.665 142.262 1.00 39.79  ? 212 ARG B C   1 
ATOM   6621  O  O   . ARG D 1 219 ? 149.313 120.349 141.378 1.00 39.79  ? 212 ARG B O   1 
ATOM   6622  C  CB  . ARG D 1 219 ? 148.921 121.028 144.433 1.00 39.79  ? 212 ARG B CB  1 
ATOM   6623  C  CG  . ARG D 1 219 ? 149.711 120.018 145.252 1.00 39.79  ? 212 ARG B CG  1 
ATOM   6624  C  CD  . ARG D 1 219 ? 148.891 119.458 146.398 1.00 39.79  ? 212 ARG B CD  1 
ATOM   6625  N  NE  . ARG D 1 219 ? 148.879 120.343 147.555 1.00 39.79  ? 212 ARG B NE  1 
ATOM   6626  C  CZ  . ARG D 1 219 ? 147.788 120.911 148.051 1.00 39.79  ? 212 ARG B CZ  1 
ATOM   6627  N  NH1 . ARG D 1 219 ? 146.599 120.716 147.505 1.00 39.79  ? 212 ARG B NH1 1 
ATOM   6628  N  NH2 . ARG D 1 219 ? 147.894 121.692 149.122 1.00 39.79  ? 212 ARG B NH2 1 
ATOM   6629  N  N   . VAL D 1 220 ? 151.338 120.152 142.362 1.00 36.17  ? 213 VAL B N   1 
ATOM   6630  C  CA  . VAL D 1 220 ? 151.916 119.259 141.365 1.00 36.17  ? 213 VAL B CA  1 
ATOM   6631  C  C   . VAL D 1 220 ? 152.504 118.049 142.075 1.00 36.17  ? 213 VAL B C   1 
ATOM   6632  O  O   . VAL D 1 220 ? 153.385 118.200 142.932 1.00 36.17  ? 213 VAL B O   1 
ATOM   6633  C  CB  . VAL D 1 220 ? 152.994 119.959 140.524 1.00 36.17  ? 213 VAL B CB  1 
ATOM   6634  C  CG1 . VAL D 1 220 ? 153.731 118.949 139.670 1.00 36.17  ? 213 VAL B CG1 1 
ATOM   6635  C  CG2 . VAL D 1 220 ? 152.362 121.020 139.655 1.00 36.17  ? 213 VAL B CG2 1 
ATOM   6636  N  N   . PHE D 1 221 ? 152.029 116.860 141.699 1.00 41.61  ? 214 PHE B N   1 
ATOM   6637  C  CA  . PHE D 1 221 ? 152.511 115.575 142.184 1.00 41.61  ? 214 PHE B CA  1 
ATOM   6638  C  C   . PHE D 1 221 ? 153.365 114.895 141.121 1.00 41.61  ? 214 PHE B C   1 
ATOM   6639  O  O   . PHE D 1 221 ? 153.174 115.105 139.921 1.00 41.61  ? 214 PHE B O   1 
ATOM   6640  C  CB  . PHE D 1 221 ? 151.357 114.630 142.534 1.00 41.61  ? 214 PHE B CB  1 
ATOM   6641  C  CG  . PHE D 1 221 ? 150.357 115.200 143.490 1.00 41.61  ? 214 PHE B CG  1 
ATOM   6642  C  CD1 . PHE D 1 221 ? 149.248 115.882 143.027 1.00 41.61  ? 214 PHE B CD1 1 
ATOM   6643  C  CD2 . PHE D 1 221 ? 150.502 115.018 144.852 1.00 41.61  ? 214 PHE B CD2 1 
ATOM   6644  C  CE1 . PHE D 1 221 ? 148.320 116.391 143.905 1.00 41.61  ? 214 PHE B CE1 1 
ATOM   6645  C  CE2 . PHE D 1 221 ? 149.574 115.526 145.733 1.00 41.61  ? 214 PHE B CE2 1 
ATOM   6646  C  CZ  . PHE D 1 221 ? 148.482 116.212 145.259 1.00 41.61  ? 214 PHE B CZ  1 
ATOM   6647  N  N   . GLN D 1 222 ? 154.282 114.046 141.577 1.00 44.79  ? 215 GLN B N   1 
ATOM   6648  C  CA  . GLN D 1 222 ? 155.117 113.222 140.712 1.00 44.79  ? 215 GLN B CA  1 
ATOM   6649  C  C   . GLN D 1 222 ? 154.614 111.785 140.741 1.00 44.79  ? 215 GLN B C   1 
ATOM   6650  O  O   . GLN D 1 222 ? 154.450 111.207 141.820 1.00 44.79  ? 215 GLN B O   1 
ATOM   6651  C  CB  . GLN D 1 222 ? 156.574 113.271 141.168 1.00 44.79  ? 215 GLN B CB  1 
ATOM   6652  C  CG  . GLN D 1 222 ? 157.505 112.325 140.446 1.00 44.79  ? 215 GLN B CG  1 
ATOM   6653  C  CD  . GLN D 1 222 ? 158.890 112.316 141.064 1.00 44.79  ? 215 GLN B CD  1 
ATOM   6654  O  OE1 . GLN D 1 222 ? 159.152 113.025 142.034 1.00 44.79  ? 215 GLN B OE1 1 
ATOM   6655  N  NE2 . GLN D 1 222 ? 159.774 111.487 140.525 1.00 44.79  ? 215 GLN B NE2 1 
ATOM   6656  N  N   . ALA D 1 223 ? 154.381 111.206 139.566 1.00 51.85  ? 216 ALA B N   1 
ATOM   6657  C  CA  . ALA D 1 223 ? 153.873 109.845 139.471 1.00 51.85  ? 216 ALA B CA  1 
ATOM   6658  C  C   . ALA D 1 223 ? 155.023 108.872 139.256 1.00 51.85  ? 216 ALA B C   1 
ATOM   6659  O  O   . ALA D 1 223 ? 155.887 109.099 138.403 1.00 51.85  ? 216 ALA B O   1 
ATOM   6660  C  CB  . ALA D 1 223 ? 152.863 109.726 138.333 1.00 51.85  ? 216 ALA B CB  1 
ATOM   6661  N  N   . THR D 1 224 ? 155.029 107.791 140.028 1.00 62.91  ? 217 THR B N   1 
ATOM   6662  C  CA  . THR D 1 224 ? 156.061 106.769 139.904 1.00 62.91  ? 217 THR B CA  1 
ATOM   6663  C  C   . THR D 1 224 ? 155.551 105.571 139.110 1.00 62.91  ? 217 THR B C   1 
ATOM   6664  O  O   . THR D 1 224 ? 155.194 104.541 139.684 1.00 62.91  ? 217 THR B O   1 
ATOM   6665  C  CB  . THR D 1 224 ? 156.550 106.290 141.282 1.00 62.91  ? 217 THR B CB  1 
ATOM   6666  O  OG1 . THR D 1 224 ? 155.424 105.949 142.099 1.00 62.91  ? 217 THR B OG1 1 
ATOM   6667  C  CG2 . THR D 1 224 ? 157.362 107.378 141.968 1.00 62.91  ? 217 THR B CG2 1 
ATOM   6668  N  N   . LYS D 1 231 ? 151.636 106.064 145.680 1.00 64.15  ? 224 LYS B N   1 
ATOM   6669  C  CA  . LYS D 1 231 ? 152.305 105.979 144.388 1.00 64.15  ? 224 LYS B CA  1 
ATOM   6670  C  C   . LYS D 1 231 ? 152.860 107.332 143.962 1.00 64.15  ? 224 LYS B C   1 
ATOM   6671  O  O   . LYS D 1 231 ? 153.847 107.406 143.230 1.00 64.15  ? 224 LYS B O   1 
ATOM   6672  C  CB  . LYS D 1 231 ? 151.346 105.452 143.320 1.00 64.15  ? 224 LYS B CB  1 
ATOM   6673  C  CG  . LYS D 1 231 ? 150.970 103.990 143.483 1.00 64.15  ? 224 LYS B CG  1 
ATOM   6674  C  CD  . LYS D 1 231 ? 150.034 103.539 142.374 1.00 64.15  ? 224 LYS B CD  1 
ATOM   6675  C  CE  . LYS D 1 231 ? 149.699 102.062 142.497 1.00 64.15  ? 224 LYS B CE  1 
ATOM   6676  N  NZ  . LYS D 1 231 ? 148.750 101.620 141.439 1.00 64.15  ? 224 LYS B NZ  1 
ATOM   6677  N  N   . CYS D 1 232 ? 152.220 108.403 144.422 1.00 58.55  ? 225 CYS B N   1 
ATOM   6678  C  CA  . CYS D 1 232 ? 152.598 109.758 144.054 1.00 58.55  ? 225 CYS B CA  1 
ATOM   6679  C  C   . CYS D 1 232 ? 152.738 110.616 145.300 1.00 58.55  ? 225 CYS B C   1 
ATOM   6680  O  O   . CYS D 1 232 ? 151.921 110.528 146.222 1.00 58.55  ? 225 CYS B O   1 
ATOM   6681  C  CB  . CYS D 1 232 ? 151.572 110.379 143.100 1.00 58.55  ? 225 CYS B CB  1 
ATOM   6682  S  SG  . CYS D 1 232 ? 149.857 110.164 143.613 1.00 58.55  ? 225 CYS B SG  1 
ATOM   6683  N  N   . SER D 1 233 ? 153.774 111.450 145.320 1.00 47.13  ? 226 SER B N   1 
ATOM   6684  C  CA  . SER D 1 233 ? 154.035 112.363 146.420 1.00 47.13  ? 226 SER B CA  1 
ATOM   6685  C  C   . SER D 1 233 ? 154.070 113.786 145.888 1.00 47.13  ? 226 SER B C   1 
ATOM   6686  O  O   . SER D 1 233 ? 154.264 114.010 144.691 1.00 47.13  ? 226 SER B O   1 
ATOM   6687  C  CB  . SER D 1 233 ? 155.357 112.034 147.122 1.00 47.13  ? 226 SER B CB  1 
ATOM   6688  O  OG  . SER D 1 233 ? 156.415 111.933 146.188 1.00 47.13  ? 226 SER B OG  1 
ATOM   6689  N  N   . VAL D 1 234 ? 153.877 114.750 146.788 1.00 42.68  ? 227 VAL B N   1 
ATOM   6690  C  CA  . VAL D 1 234 ? 153.802 116.144 146.371 1.00 42.68  ? 227 VAL B CA  1 
ATOM   6691  C  C   . VAL D 1 234 ? 155.167 116.626 145.897 1.00 42.68  ? 227 VAL B C   1 
ATOM   6692  O  O   . VAL D 1 234 ? 156.219 116.159 146.352 1.00 42.68  ? 227 VAL B O   1 
ATOM   6693  C  CB  . VAL D 1 234 ? 153.263 117.031 147.508 1.00 42.68  ? 227 VAL B CB  1 
ATOM   6694  C  CG1 . VAL D 1 234 ? 152.080 116.365 148.166 1.00 42.68  ? 227 VAL B CG1 1 
ATOM   6695  C  CG2 . VAL D 1 234 ? 154.350 117.324 148.527 1.00 42.68  ? 227 VAL B CG2 1 
ATOM   6696  N  N   . VAL D 1 235 ? 155.146 117.558 144.947 1.00 36.91  ? 228 VAL B N   1 
ATOM   6697  C  CA  . VAL D 1 235 ? 156.345 118.194 144.419 1.00 36.91  ? 228 VAL B CA  1 
ATOM   6698  C  C   . VAL D 1 235 ? 156.268 119.709 144.547 1.00 36.91  ? 228 VAL B C   1 
ATOM   6699  O  O   . VAL D 1 235 ? 157.202 120.351 145.033 1.00 36.91  ? 228 VAL B O   1 
ATOM   6700  C  CB  . VAL D 1 235 ? 156.598 117.784 142.952 1.00 36.91  ? 228 VAL B CB  1 
ATOM   6701  C  CG1 . VAL D 1 235 ? 157.897 118.370 142.450 1.00 36.91  ? 228 VAL B CG1 1 
ATOM   6702  C  CG2 . VAL D 1 235 ? 156.636 116.287 142.840 1.00 36.91  ? 228 VAL B CG2 1 
ATOM   6703  N  N   . LEU D 1 236 ? 155.154 120.297 144.122 1.00 36.75  ? 229 LEU B N   1 
ATOM   6704  C  CA  . LEU D 1 236 ? 154.969 121.739 144.210 1.00 36.75  ? 229 LEU B CA  1 
ATOM   6705  C  C   . LEU D 1 236 ? 153.635 122.047 144.870 1.00 36.75  ? 229 LEU B C   1 
ATOM   6706  O  O   . LEU D 1 236 ? 152.639 121.362 144.632 1.00 36.75  ? 229 LEU B O   1 
ATOM   6707  C  CB  . LEU D 1 236 ? 155.021 122.407 142.832 1.00 36.75  ? 229 LEU B CB  1 
ATOM   6708  C  CG  . LEU D 1 236 ? 156.370 122.427 142.122 1.00 36.75  ? 229 LEU B CG  1 
ATOM   6709  C  CD1 . LEU D 1 236 ? 156.298 123.310 140.892 1.00 36.75  ? 229 LEU B CD1 1 
ATOM   6710  C  CD2 . LEU D 1 236 ? 157.457 122.903 143.062 1.00 36.75  ? 229 LEU B CD2 1 
ATOM   6711  N  N   . GLY D 1 237 ? 153.619 123.099 145.682 1.00 38.80  ? 230 GLY B N   1 
ATOM   6712  C  CA  . GLY D 1 237 ? 152.414 123.497 146.369 1.00 38.80  ? 230 GLY B CA  1 
ATOM   6713  C  C   . GLY D 1 237 ? 152.566 124.792 147.136 1.00 38.80  ? 230 GLY B C   1 
ATOM   6714  O  O   . GLY D 1 237 ? 153.550 125.522 146.985 1.00 38.80  ? 230 GLY B O   1 
ATOM   6715  N  N   . PRO D 1 238 ? 151.584 125.100 147.989 1.00 38.60  ? 231 PRO B N   1 
ATOM   6716  C  CA  . PRO D 1 238 ? 151.617 126.365 148.739 1.00 38.60  ? 231 PRO B CA  1 
ATOM   6717  C  C   . PRO D 1 238 ? 152.704 126.442 149.798 1.00 38.60  ? 231 PRO B C   1 
ATOM   6718  O  O   . PRO D 1 238 ? 152.755 127.439 150.527 1.00 38.60  ? 231 PRO B O   1 
ATOM   6719  C  CB  . PRO D 1 238 ? 150.223 126.420 149.381 1.00 38.60  ? 231 PRO B CB  1 
ATOM   6720  C  CG  . PRO D 1 238 ? 149.778 125.006 149.439 1.00 38.60  ? 231 PRO B CG  1 
ATOM   6721  C  CD  . PRO D 1 238 ? 150.334 124.359 148.213 1.00 38.60  ? 231 PRO B CD  1 
ATOM   6722  N  N   . LYS D 1 239 ? 153.567 125.434 149.923 1.00 43.10  ? 232 LYS B N   1 
ATOM   6723  C  CA  . LYS D 1 239 ? 154.681 125.493 150.857 1.00 43.10  ? 232 LYS B CA  1 
ATOM   6724  C  C   . LYS D 1 239 ? 156.028 125.155 150.234 1.00 43.10  ? 232 LYS B C   1 
ATOM   6725  O  O   . LYS D 1 239 ? 157.055 125.380 150.881 1.00 43.10  ? 232 LYS B O   1 
ATOM   6726  C  CB  . LYS D 1 239 ? 154.436 124.557 152.052 1.00 43.10  ? 232 LYS B CB  1 
ATOM   6727  C  CG  . LYS D 1 239 ? 153.179 124.881 152.846 1.00 43.10  ? 232 LYS B CG  1 
ATOM   6728  C  CD  . LYS D 1 239 ? 153.011 123.945 154.031 1.00 43.10  ? 232 LYS B CD  1 
ATOM   6729  C  CE  . LYS D 1 239 ? 151.557 123.549 154.222 1.00 43.10  ? 232 LYS B CE  1 
ATOM   6730  N  NZ  . LYS D 1 239 ? 151.096 122.602 153.168 1.00 43.10  ? 232 LYS B NZ  1 
ATOM   6731  N  N   . TRP D 1 240 ? 156.061 124.630 149.013 1.00 39.57  ? 233 TRP B N   1 
ATOM   6732  C  CA  . TRP D 1 240 ? 157.308 124.335 148.308 1.00 39.57  ? 233 TRP B CA  1 
ATOM   6733  C  C   . TRP D 1 240 ? 157.313 125.079 146.980 1.00 39.57  ? 233 TRP B C   1 
ATOM   6734  O  O   . TRP D 1 240 ? 156.781 124.566 145.979 1.00 39.57  ? 233 TRP B O   1 
ATOM   6735  C  CB  . TRP D 1 240 ? 157.468 122.834 148.078 1.00 39.57  ? 233 TRP B CB  1 
ATOM   6736  C  CG  . TRP D 1 240 ? 157.390 122.012 149.320 1.00 39.57  ? 233 TRP B CG  1 
ATOM   6737  C  CD1 . TRP D 1 240 ? 158.419 121.678 150.147 1.00 39.57  ? 233 TRP B CD1 1 
ATOM   6738  C  CD2 . TRP D 1 240 ? 156.215 121.411 149.877 1.00 39.57  ? 233 TRP B CD2 1 
ATOM   6739  N  NE1 . TRP D 1 240 ? 157.959 120.906 151.187 1.00 39.57  ? 233 TRP B NE1 1 
ATOM   6740  C  CE2 . TRP D 1 240 ? 156.609 120.728 151.043 1.00 39.57  ? 233 TRP B CE2 1 
ATOM   6741  C  CE3 . TRP D 1 240 ? 154.869 121.384 149.504 1.00 39.57  ? 233 TRP B CE3 1 
ATOM   6742  C  CZ2 . TRP D 1 240 ? 155.706 120.029 151.839 1.00 39.57  ? 233 TRP B CZ2 1 
ATOM   6743  C  CZ3 . TRP D 1 240 ? 153.974 120.688 150.293 1.00 39.57  ? 233 TRP B CZ3 1 
ATOM   6744  C  CH2 . TRP D 1 240 ? 154.396 120.021 151.447 1.00 39.57  ? 233 TRP B CH2 1 
ATOM   6745  N  N   . PRO D 1 241 ? 157.863 126.291 146.922 1.00 30.69  ? 234 PRO B N   1 
ATOM   6746  C  CA  . PRO D 1 241 ? 157.918 127.007 145.637 1.00 30.69  ? 234 PRO B CA  1 
ATOM   6747  C  C   . PRO D 1 241 ? 158.633 126.245 144.534 1.00 30.69  ? 234 PRO B C   1 
ATOM   6748  O  O   . PRO D 1 241 ? 158.211 126.308 143.375 1.00 30.69  ? 234 PRO B O   1 
ATOM   6749  C  CB  . PRO D 1 241 ? 158.669 128.297 145.985 1.00 30.69  ? 234 PRO B CB  1 
ATOM   6750  C  CG  . PRO D 1 241 ? 158.622 128.424 147.471 1.00 30.69  ? 234 PRO B CG  1 
ATOM   6751  C  CD  . PRO D 1 241 ? 158.038 127.188 148.072 1.00 30.69  ? 234 PRO B CD  1 
ATOM   6752  N  N   . SER D 1 242 ? 159.705 125.526 144.858 1.00 31.80  ? 235 SER B N   1 
ATOM   6753  C  CA  . SER D 1 242 ? 160.498 124.845 143.845 1.00 31.80  ? 235 SER B CA  1 
ATOM   6754  C  C   . SER D 1 242 ? 160.942 123.490 144.371 1.00 31.80  ? 235 SER B C   1 
ATOM   6755  O  O   . SER D 1 242 ? 161.050 123.276 145.580 1.00 31.80  ? 235 SER B O   1 
ATOM   6756  C  CB  . SER D 1 242 ? 161.722 125.669 143.442 1.00 31.80  ? 235 SER B CB  1 
ATOM   6757  O  OG  . SER D 1 242 ? 162.606 125.817 144.538 1.00 31.80  ? 235 SER B OG  1 
ATOM   6758  N  N   . HIS D 1 243 ? 161.210 122.574 143.442 1.00 35.98  ? 236 HIS B N   1 
ATOM   6759  C  CA  . HIS D 1 243 ? 161.701 121.253 143.802 1.00 35.98  ? 236 HIS B CA  1 
ATOM   6760  C  C   . HIS D 1 243 ? 162.757 120.794 142.809 1.00 35.98  ? 236 HIS B C   1 
ATOM   6761  O  O   . HIS D 1 243 ? 162.593 120.943 141.594 1.00 35.98  ? 236 HIS B O   1 
ATOM   6762  C  CB  . HIS D 1 243 ? 160.569 120.225 143.861 1.00 35.98  ? 236 HIS B CB  1 
ATOM   6763  C  CG  . HIS D 1 243 ? 160.924 118.982 144.616 1.00 35.98  ? 236 HIS B CG  1 
ATOM   6764  N  ND1 . HIS D 1 243 ? 160.041 117.939 144.793 1.00 35.98  ? 236 HIS B ND1 1 
ATOM   6765  C  CD2 . HIS D 1 243 ? 162.065 118.617 145.245 1.00 35.98  ? 236 HIS B CD2 1 
ATOM   6766  C  CE1 . HIS D 1 243 ? 160.623 116.984 145.495 1.00 35.98  ? 236 HIS B CE1 1 
ATOM   6767  N  NE2 . HIS D 1 243 ? 161.853 117.370 145.783 1.00 35.98  ? 236 HIS B NE2 1 
ATOM   6768  N  N   . TYR D 1 244 ? 163.838 120.236 143.343 1.00 35.91  ? 237 TYR B N   1 
ATOM   6769  C  CA  . TYR D 1 244 ? 164.874 119.623 142.528 1.00 35.91  ? 237 TYR B CA  1 
ATOM   6770  C  C   . TYR D 1 244 ? 164.449 118.218 142.125 1.00 35.91  ? 237 TYR B C   1 
ATOM   6771  O  O   . TYR D 1 244 ? 163.911 117.461 142.936 1.00 35.91  ? 237 TYR B O   1 
ATOM   6772  C  CB  . TYR D 1 244 ? 166.191 119.574 143.303 1.00 35.91  ? 237 TYR B CB  1 
ATOM   6773  C  CG  . TYR D 1 244 ? 166.771 120.937 143.604 1.00 35.91  ? 237 TYR B CG  1 
ATOM   6774  C  CD1 . TYR D 1 244 ? 167.514 121.621 142.656 1.00 35.91  ? 237 TYR B CD1 1 
ATOM   6775  C  CD2 . TYR D 1 244 ? 166.553 121.551 144.829 1.00 35.91  ? 237 TYR B CD2 1 
ATOM   6776  C  CE1 . TYR D 1 244 ? 168.042 122.867 142.924 1.00 35.91  ? 237 TYR B CE1 1 
ATOM   6777  C  CE2 . TYR D 1 244 ? 167.074 122.799 145.104 1.00 35.91  ? 237 TYR B CE2 1 
ATOM   6778  C  CZ  . TYR D 1 244 ? 167.817 123.451 144.148 1.00 35.91  ? 237 TYR B CZ  1 
ATOM   6779  O  OH  . TYR D 1 244 ? 168.339 124.695 144.415 1.00 35.91  ? 237 TYR B OH  1 
ATOM   6780  N  N   . LEU D 1 245 ? 164.691 117.871 140.866 1.00 40.36  ? 238 LEU B N   1 
ATOM   6781  C  CA  . LEU D 1 245 ? 164.271 116.591 140.319 1.00 40.36  ? 238 LEU B CA  1 
ATOM   6782  C  C   . LEU D 1 245 ? 165.450 115.632 140.210 1.00 40.36  ? 238 LEU B C   1 
ATOM   6783  O  O   . LEU D 1 245 ? 166.563 116.024 139.856 1.00 40.36  ? 238 LEU B O   1 
ATOM   6784  C  CB  . LEU D 1 245 ? 163.625 116.770 138.945 1.00 40.36  ? 238 LEU B CB  1 
ATOM   6785  C  CG  . LEU D 1 245 ? 162.329 117.577 138.899 1.00 40.36  ? 238 LEU B CG  1 
ATOM   6786  C  CD1 . LEU D 1 245 ? 161.884 117.781 137.464 1.00 40.36  ? 238 LEU B CD1 1 
ATOM   6787  C  CD2 . LEU D 1 245 ? 161.247 116.882 139.701 1.00 40.36  ? 238 LEU B CD2 1 
ATOM   6788  N  N   . MET D 1 246 ? 165.188 114.365 140.522 1.00 52.99  ? 239 MET B N   1 
ATOM   6789  C  CA  . MET D 1 246 ? 166.169 113.294 140.392 1.00 52.99  ? 239 MET B CA  1 
ATOM   6790  C  C   . MET D 1 246 ? 165.830 112.491 139.142 1.00 52.99  ? 239 MET B C   1 
ATOM   6791  O  O   . MET D 1 246 ? 164.810 111.797 139.104 1.00 52.99  ? 239 MET B O   1 
ATOM   6792  C  CB  . MET D 1 246 ? 166.173 112.403 141.631 1.00 52.99  ? 239 MET B CB  1 
ATOM   6793  C  CG  . MET D 1 246 ? 166.236 113.160 142.946 1.00 52.99  ? 239 MET B CG  1 
ATOM   6794  S  SD  . MET D 1 246 ? 166.244 112.079 144.392 1.00 52.99  ? 239 MET B SD  1 
ATOM   6795  C  CE  . MET D 1 246 ? 166.311 110.460 143.627 1.00 52.99  ? 239 MET B CE  1 
ATOM   6796  N  N   . VAL D 1 247 ? 166.682 112.583 138.127 1.00 57.89  ? 240 VAL B N   1 
ATOM   6797  C  CA  . VAL D 1 247 ? 166.461 111.938 136.840 1.00 57.89  ? 240 VAL B CA  1 
ATOM   6798  C  C   . VAL D 1 247 ? 167.708 111.137 136.489 1.00 57.89  ? 240 VAL B C   1 
ATOM   6799  O  O   . VAL D 1 247 ? 168.820 111.627 136.690 1.00 57.89  ? 240 VAL B O   1 
ATOM   6800  C  CB  . VAL D 1 247 ? 166.150 112.947 135.721 1.00 57.89  ? 240 VAL B CB  1 
ATOM   6801  C  CG1 . VAL D 1 247 ? 166.052 112.241 134.393 1.00 57.89  ? 240 VAL B CG1 1 
ATOM   6802  C  CG2 . VAL D 1 247 ? 164.857 113.667 136.024 1.00 57.89  ? 240 VAL B CG2 1 
ATOM   6803  N  N   . PRO D 1 248 ? 167.574 109.919 135.975 1.00 62.58  ? 241 PRO B N   1 
ATOM   6804  C  CA  . PRO D 1 248 ? 168.742 109.165 135.516 1.00 62.58  ? 241 PRO B CA  1 
ATOM   6805  C  C   . PRO D 1 248 ? 169.117 109.516 134.083 1.00 62.58  ? 241 PRO B C   1 
ATOM   6806  O  O   . PRO D 1 248 ? 168.367 110.160 133.348 1.00 62.58  ? 241 PRO B O   1 
ATOM   6807  C  CB  . PRO D 1 248 ? 168.267 107.710 135.613 1.00 62.58  ? 241 PRO B CB  1 
ATOM   6808  C  CG  . PRO D 1 248 ? 166.803 107.799 135.345 1.00 62.58  ? 241 PRO B CG  1 
ATOM   6809  C  CD  . PRO D 1 248 ? 166.338 109.122 135.908 1.00 62.58  ? 241 PRO B CD  1 
ATOM   6810  N  N   . GLY D 1 249 ? 170.307 109.071 133.697 1.00 65.22  ? 242 GLY B N   1 
ATOM   6811  C  CA  . GLY D 1 249 ? 170.795 109.315 132.357 1.00 65.22  ? 242 GLY B CA  1 
ATOM   6812  C  C   . GLY D 1 249 ? 170.149 108.403 131.330 1.00 65.22  ? 242 GLY B C   1 
ATOM   6813  O  O   . GLY D 1 249 ? 169.427 107.456 131.642 1.00 65.22  ? 242 GLY B O   1 
ATOM   6814  N  N   . GLY D 1 250 ? 170.425 108.708 130.064 1.00 64.19  ? 243 GLY B N   1 
ATOM   6815  C  CA  . GLY D 1 250 ? 169.872 107.948 128.961 1.00 64.19  ? 243 GLY B CA  1 
ATOM   6816  C  C   . GLY D 1 250 ? 168.548 108.498 128.476 1.00 64.19  ? 243 GLY B C   1 
ATOM   6817  O  O   . GLY D 1 250 ? 168.400 109.713 128.308 1.00 64.19  ? 243 GLY B O   1 
ATOM   6818  N  N   . LYS D 1 251 ? 167.589 107.610 128.229 1.00 64.24  ? 244 LYS B N   1 
ATOM   6819  C  CA  . LYS D 1 251 ? 166.217 107.982 127.921 1.00 64.24  ? 244 LYS B CA  1 
ATOM   6820  C  C   . LYS D 1 251 ? 165.381 107.889 129.187 1.00 64.24  ? 244 LYS B C   1 
ATOM   6821  O  O   . LYS D 1 251 ? 165.523 106.938 129.962 1.00 64.24  ? 244 LYS B O   1 
ATOM   6822  C  CB  . LYS D 1 251 ? 165.616 107.063 126.856 1.00 64.24  ? 244 LYS B CB  1 
ATOM   6823  C  CG  . LYS D 1 251 ? 166.209 107.190 125.469 1.00 64.24  ? 244 LYS B CG  1 
ATOM   6824  C  CD  . LYS D 1 251 ? 165.408 106.355 124.480 1.00 64.24  ? 244 LYS B CD  1 
ATOM   6825  C  CE  . LYS D 1 251 ? 166.074 106.304 123.116 1.00 64.24  ? 244 LYS B CE  1 
ATOM   6826  N  NZ  . LYS D 1 251 ? 165.306 105.462 122.156 1.00 64.24  ? 244 LYS B NZ  1 
ATOM   6827  N  N   . HIS D 1 252 ? 164.507 108.869 129.398 1.00 59.16  ? 245 HIS B N   1 
ATOM   6828  C  CA  . HIS D 1 252 ? 163.600 108.777 130.533 1.00 59.16  ? 245 HIS B CA  1 
ATOM   6829  C  C   . HIS D 1 252 ? 162.399 109.681 130.303 1.00 59.16  ? 245 HIS B C   1 
ATOM   6830  O  O   . HIS D 1 252 ? 162.482 110.684 129.586 1.00 59.16  ? 245 HIS B O   1 
ATOM   6831  C  CB  . HIS D 1 252 ? 164.296 109.146 131.846 1.00 59.16  ? 245 HIS B CB  1 
ATOM   6832  C  CG  . HIS D 1 252 ? 163.505 108.786 133.065 1.00 59.16  ? 245 HIS B CG  1 
ATOM   6833  N  ND1 . HIS D 1 252 ? 162.994 109.730 133.927 1.00 59.16  ? 245 HIS B ND1 1 
ATOM   6834  C  CD2 . HIS D 1 252 ? 163.133 107.583 133.560 1.00 59.16  ? 245 HIS B CD2 1 
ATOM   6835  C  CE1 . HIS D 1 252 ? 162.345 109.124 134.905 1.00 59.16  ? 245 HIS B CE1 1 
ATOM   6836  N  NE2 . HIS D 1 252 ? 162.413 107.820 134.705 1.00 59.16  ? 245 HIS B NE2 1 
ATOM   6837  N  N   . ASN D 1 253 ? 161.285 109.309 130.924 1.00 54.79  ? 246 ASN B N   1 
ATOM   6838  C  CA  . ASN D 1 253 ? 160.065 110.098 130.905 1.00 54.79  ? 246 ASN B CA  1 
ATOM   6839  C  C   . ASN D 1 253 ? 159.519 110.190 132.319 1.00 54.79  ? 246 ASN B C   1 
ATOM   6840  O  O   . ASN D 1 253 ? 159.518 109.204 133.060 1.00 54.79  ? 246 ASN B O   1 
ATOM   6841  C  CB  . ASN D 1 253 ? 159.021 109.483 129.972 1.00 54.79  ? 246 ASN B CB  1 
ATOM   6842  C  CG  . ASN D 1 253 ? 159.538 109.313 128.559 1.00 54.79  ? 246 ASN B CG  1 
ATOM   6843  O  OD1 . ASN D 1 253 ? 159.825 110.291 127.869 1.00 54.79  ? 246 ASN B OD1 1 
ATOM   6844  N  ND2 . ASN D 1 253 ? 159.661 108.067 128.119 1.00 54.79  ? 246 ASN B ND2 1 
ATOM   6845  N  N   . MET D 1 254 ? 159.062 111.380 132.690 1.00 48.76  ? 247 MET B N   1 
ATOM   6846  C  CA  . MET D 1 254 ? 158.477 111.625 133.999 1.00 48.76  ? 247 MET B CA  1 
ATOM   6847  C  C   . MET D 1 254 ? 157.063 112.153 133.830 1.00 48.76  ? 247 MET B C   1 
ATOM   6848  O  O   . MET D 1 254 ? 156.795 112.958 132.932 1.00 48.76  ? 247 MET B O   1 
ATOM   6849  C  CB  . MET D 1 254 ? 159.305 112.621 134.809 1.00 48.76  ? 247 MET B CB  1 
ATOM   6850  C  CG  . MET D 1 254 ? 160.653 112.104 135.252 1.00 48.76  ? 247 MET B CG  1 
ATOM   6851  S  SD  . MET D 1 254 ? 161.338 113.152 136.541 1.00 48.76  ? 247 MET B SD  1 
ATOM   6852  C  CE  . MET D 1 254 ? 160.038 113.054 137.760 1.00 48.76  ? 247 MET B CE  1 
ATOM   6853  N  N   . ASP D 1 255 ? 156.169 111.706 134.706 1.00 47.34  ? 248 ASP B N   1 
ATOM   6854  C  CA  . ASP D 1 255 ? 154.768 112.092 134.673 1.00 47.34  ? 248 ASP B CA  1 
ATOM   6855  C  C   . ASP D 1 255 ? 154.459 112.969 135.878 1.00 47.34  ? 248 ASP B C   1 
ATOM   6856  O  O   . ASP D 1 255 ? 154.739 112.585 137.019 1.00 47.34  ? 248 ASP B O   1 
ATOM   6857  C  CB  . ASP D 1 255 ? 153.864 110.859 134.665 1.00 47.34  ? 248 ASP B CB  1 
ATOM   6858  C  CG  . ASP D 1 255 ? 153.720 110.255 133.284 1.00 47.34  ? 248 ASP B CG  1 
ATOM   6859  O  OD1 . ASP D 1 255 ? 154.298 110.811 132.329 1.00 47.34  ? 248 ASP B OD1 1 
ATOM   6860  O  OD2 . ASP D 1 255 ? 153.033 109.220 133.155 1.00 47.34  ? 248 ASP B OD2 1 
ATOM   6861  N  N   . PHE D 1 256 ? 153.889 114.141 135.622 1.00 39.82  ? 249 PHE B N   1 
ATOM   6862  C  CA  . PHE D 1 256 ? 153.476 115.067 136.661 1.00 39.82  ? 249 PHE B CA  1 
ATOM   6863  C  C   . PHE D 1 256 ? 151.978 115.298 136.551 1.00 39.82  ? 249 PHE B C   1 
ATOM   6864  O  O   . PHE D 1 256 ? 151.437 115.396 135.445 1.00 39.82  ? 249 PHE B O   1 
ATOM   6865  C  CB  . PHE D 1 256 ? 154.218 116.399 136.546 1.00 39.82  ? 249 PHE B CB  1 
ATOM   6866  C  CG  . PHE D 1 256 ? 155.676 116.313 136.881 1.00 39.82  ? 249 PHE B CG  1 
ATOM   6867  C  CD1 . PHE D 1 256 ? 156.125 116.626 138.150 1.00 39.82  ? 249 PHE B CD1 1 
ATOM   6868  C  CD2 . PHE D 1 256 ? 156.597 115.919 135.931 1.00 39.82  ? 249 PHE B CD2 1 
ATOM   6869  C  CE1 . PHE D 1 256 ? 157.465 116.551 138.461 1.00 39.82  ? 249 PHE B CE1 1 
ATOM   6870  C  CE2 . PHE D 1 256 ? 157.937 115.840 136.238 1.00 39.82  ? 249 PHE B CE2 1 
ATOM   6871  C  CZ  . PHE D 1 256 ? 158.372 116.157 137.504 1.00 39.82  ? 249 PHE B CZ  1 
ATOM   6872  N  N   . TYR D 1 257 ? 151.313 115.376 137.695 1.00 38.98  ? 250 TYR B N   1 
ATOM   6873  C  CA  . TYR D 1 257 ? 149.880 115.625 137.752 1.00 38.98  ? 250 TYR B CA  1 
ATOM   6874  C  C   . TYR D 1 257 ? 149.641 116.965 138.428 1.00 38.98  ? 250 TYR B C   1 
ATOM   6875  O  O   . TYR D 1 257 ? 150.164 117.214 139.518 1.00 38.98  ? 250 TYR B O   1 
ATOM   6876  C  CB  . TYR D 1 257 ? 149.157 114.504 138.500 1.00 38.98  ? 250 TYR B CB  1 
ATOM   6877  C  CG  . TYR D 1 257 ? 149.041 113.226 137.705 1.00 38.98  ? 250 TYR B CG  1 
ATOM   6878  C  CD1 . TYR D 1 257 ? 148.059 113.076 136.738 1.00 38.98  ? 250 TYR B CD1 1 
ATOM   6879  C  CD2 . TYR D 1 257 ? 149.916 112.173 137.915 1.00 38.98  ? 250 TYR B CD2 1 
ATOM   6880  C  CE1 . TYR D 1 257 ? 147.951 111.914 136.006 1.00 38.98  ? 250 TYR B CE1 1 
ATOM   6881  C  CE2 . TYR D 1 257 ? 149.815 111.007 137.186 1.00 38.98  ? 250 TYR B CE2 1 
ATOM   6882  C  CZ  . TYR D 1 257 ? 148.831 110.883 136.234 1.00 38.98  ? 250 TYR B CZ  1 
ATOM   6883  O  OH  . TYR D 1 257 ? 148.728 109.721 135.507 1.00 38.98  ? 250 TYR B OH  1 
ATOM   6884  N  N   . VAL D 1 258 ? 148.851 117.820 137.784 1.00 37.19  ? 251 VAL B N   1 
ATOM   6885  C  CA  . VAL D 1 258 ? 148.652 119.197 138.214 1.00 37.19  ? 251 VAL B CA  1 
ATOM   6886  C  C   . VAL D 1 258 ? 147.186 119.399 138.564 1.00 37.19  ? 251 VAL B C   1 
ATOM   6887  O  O   . VAL D 1 258 ? 146.301 118.966 137.816 1.00 37.19  ? 251 VAL B O   1 
ATOM   6888  C  CB  . VAL D 1 258 ? 149.089 120.194 137.128 1.00 37.19  ? 251 VAL B CB  1 
ATOM   6889  C  CG1 . VAL D 1 258 ? 149.191 121.584 137.707 1.00 37.19  ? 251 VAL B CG1 1 
ATOM   6890  C  CG2 . VAL D 1 258 ? 150.410 119.768 136.525 1.00 37.19  ? 251 VAL B CG2 1 
ATOM   6891  N  N   . GLU D 1 259 ? 146.933 120.052 139.698 1.00 38.74  ? 252 GLU B N   1 
ATOM   6892  C  CA  . GLU D 1 259 ? 145.585 120.423 140.102 1.00 38.74  ? 252 GLU B CA  1 
ATOM   6893  C  C   . GLU D 1 259 ? 145.577 121.847 140.635 1.00 38.74  ? 252 GLU B C   1 
ATOM   6894  O  O   . GLU D 1 259 ? 146.460 122.240 141.404 1.00 38.74  ? 252 GLU B O   1 
ATOM   6895  C  CB  . GLU D 1 259 ? 145.026 119.463 141.163 1.00 38.74  ? 252 GLU B CB  1 
ATOM   6896  C  CG  . GLU D 1 259 ? 145.848 119.368 142.439 1.00 38.74  ? 252 GLU B CG  1 
ATOM   6897  C  CD  . GLU D 1 259 ? 145.212 118.456 143.472 1.00 38.74  ? 252 GLU B CD  1 
ATOM   6898  O  OE1 . GLU D 1 259 ? 144.084 117.980 143.228 1.00 38.74  ? 252 GLU B OE1 1 
ATOM   6899  O  OE2 . GLU D 1 259 ? 145.839 118.210 144.523 1.00 38.74  ? 252 GLU B OE2 1 
ATOM   6900  N  N   . ALA D 1 260 ? 144.573 122.616 140.227 1.00 35.01  ? 253 ALA B N   1 
ATOM   6901  C  CA  . ALA D 1 260 ? 144.405 123.990 140.670 1.00 35.01  ? 253 ALA B CA  1 
ATOM   6902  C  C   . ALA D 1 260 ? 143.637 124.032 141.983 1.00 35.01  ? 253 ALA B C   1 
ATOM   6903  O  O   . ALA D 1 260 ? 142.994 123.061 142.385 1.00 35.01  ? 253 ALA B O   1 
ATOM   6904  C  CB  . ALA D 1 260 ? 143.678 124.820 139.610 1.00 35.01  ? 253 ALA B CB  1 
ATOM   6905  N  N   . LEU D 1 261 ? 143.715 125.178 142.657 1.00 34.64  ? 254 LEU B N   1 
ATOM   6906  C  CA  . LEU D 1 261 ? 143.103 125.343 143.968 1.00 34.64  ? 254 LEU B CA  1 
ATOM   6907  C  C   . LEU D 1 261 ? 142.036 126.423 144.027 1.00 34.64  ? 254 LEU B C   1 
ATOM   6908  O  O   . LEU D 1 261 ? 141.113 126.310 144.834 1.00 34.64  ? 254 LEU B O   1 
ATOM   6909  C  CB  . LEU D 1 261 ? 144.175 125.659 145.017 1.00 34.64  ? 254 LEU B CB  1 
ATOM   6910  C  CG  . LEU D 1 261 ? 144.612 124.518 145.936 1.00 34.64  ? 254 LEU B CG  1 
ATOM   6911  C  CD1 . LEU D 1 261 ? 143.573 124.294 147.017 1.00 34.64  ? 254 LEU B CD1 1 
ATOM   6912  C  CD2 . LEU D 1 261 ? 144.851 123.244 145.149 1.00 34.64  ? 254 LEU B CD2 1 
ATOM   6913  N  N   . ALA D 1 262 ? 142.132 127.462 143.201 1.00 32.51  ? 255 ALA B N   1 
ATOM   6914  C  CA  . ALA D 1 262 ? 141.223 128.596 143.280 1.00 32.51  ? 255 ALA B CA  1 
ATOM   6915  C  C   . ALA D 1 262 ? 140.633 128.905 141.914 1.00 32.51  ? 255 ALA B C   1 
ATOM   6916  O  O   . ALA D 1 262 ? 141.328 128.841 140.897 1.00 32.51  ? 255 ALA B O   1 
ATOM   6917  C  CB  . ALA D 1 262 ? 141.934 129.838 143.826 1.00 32.51  ? 255 ALA B CB  1 
ATOM   6918  N  N   . PHE D 1 263 ? 139.346 129.237 141.900 1.00 30.76  ? 256 PHE B N   1 
ATOM   6919  C  CA  . PHE D 1 263 ? 138.711 129.705 140.682 1.00 30.76  ? 256 PHE B CA  1 
ATOM   6920  C  C   . PHE D 1 263 ? 139.232 131.099 140.336 1.00 30.76  ? 256 PHE B C   1 
ATOM   6921  O  O   . PHE D 1 263 ? 139.704 131.824 141.215 1.00 30.76  ? 256 PHE B O   1 
ATOM   6922  C  CB  . PHE D 1 263 ? 137.195 129.742 140.850 1.00 30.76  ? 256 PHE B CB  1 
ATOM   6923  C  CG  . PHE D 1 263 ? 136.513 128.451 140.506 1.00 30.76  ? 256 PHE B CG  1 
ATOM   6924  C  CD1 . PHE D 1 263 ? 136.611 127.356 141.341 1.00 30.76  ? 256 PHE B CD1 1 
ATOM   6925  C  CD2 . PHE D 1 263 ? 135.776 128.333 139.344 1.00 30.76  ? 256 PHE B CD2 1 
ATOM   6926  C  CE1 . PHE D 1 263 ? 135.981 126.173 141.026 1.00 30.76  ? 256 PHE B CE1 1 
ATOM   6927  C  CE2 . PHE D 1 263 ? 135.148 127.151 139.024 1.00 30.76  ? 256 PHE B CE2 1 
ATOM   6928  C  CZ  . PHE D 1 263 ? 135.251 126.070 139.864 1.00 30.76  ? 256 PHE B CZ  1 
ATOM   6929  N  N   . PRO D 1 264 ? 139.177 131.493 139.064 1.00 31.08  ? 257 PRO B N   1 
ATOM   6930  C  CA  . PRO D 1 264 ? 139.639 132.835 138.697 1.00 31.08  ? 257 PRO B CA  1 
ATOM   6931  C  C   . PRO D 1 264 ? 138.808 133.907 139.384 1.00 31.08  ? 257 PRO B C   1 
ATOM   6932  O  O   . PRO D 1 264 ? 137.602 133.755 139.579 1.00 31.08  ? 257 PRO B O   1 
ATOM   6933  C  CB  . PRO D 1 264 ? 139.460 132.871 137.175 1.00 31.08  ? 257 PRO B CB  1 
ATOM   6934  C  CG  . PRO D 1 264 ? 139.395 131.447 136.762 1.00 31.08  ? 257 PRO B CG  1 
ATOM   6935  C  CD  . PRO D 1 264 ? 138.726 130.733 137.888 1.00 31.08  ? 257 PRO B CD  1 
ATOM   6936  N  N   . ASP D 1 265 ? 139.469 134.999 139.751 1.00 37.21  ? 258 ASP B N   1 
ATOM   6937  C  CA  . ASP D 1 265 ? 138.822 136.092 140.462 1.00 37.21  ? 258 ASP B CA  1 
ATOM   6938  C  C   . ASP D 1 265 ? 139.506 137.393 140.056 1.00 37.21  ? 258 ASP B C   1 
ATOM   6939  O  O   . ASP D 1 265 ? 140.338 137.417 139.145 1.00 37.21  ? 258 ASP B O   1 
ATOM   6940  C  CB  . ASP D 1 265 ? 138.870 135.848 141.974 1.00 37.21  ? 258 ASP B CB  1 
ATOM   6941  C  CG  . ASP D 1 265 ? 137.608 136.299 142.674 1.00 37.21  ? 258 ASP B CG  1 
ATOM   6942  O  OD1 . ASP D 1 265 ? 136.717 136.849 141.996 1.00 37.21  ? 258 ASP B OD1 1 
ATOM   6943  O  OD2 . ASP D 1 265 ? 137.504 136.100 143.903 1.00 37.21  ? 258 ASP B OD2 1 
ATOM   6944  N  N   . THR D 1 266 ? 139.147 138.487 140.731 1.00 40.12  ? 259 THR B N   1 
ATOM   6945  C  CA  . THR D 1 266 ? 139.752 139.778 140.412 1.00 40.12  ? 259 THR B CA  1 
ATOM   6946  C  C   . THR D 1 266 ? 141.244 139.786 140.719 1.00 40.12  ? 259 THR B C   1 
ATOM   6947  O  O   . THR D 1 266 ? 142.036 140.364 139.966 1.00 40.12  ? 259 THR B O   1 
ATOM   6948  C  CB  . THR D 1 266 ? 139.046 140.900 141.169 1.00 40.12  ? 259 THR B CB  1 
ATOM   6949  O  OG1 . THR D 1 266 ? 138.665 140.440 142.471 1.00 40.12  ? 259 THR B OG1 1 
ATOM   6950  C  CG2 . THR D 1 266 ? 137.816 141.360 140.410 1.00 40.12  ? 259 THR B CG2 1 
ATOM   6951  N  N   . ASP D 1 267 ? 141.646 139.160 141.823 1.00 42.85  ? 260 ASP B N   1 
ATOM   6952  C  CA  . ASP D 1 267 ? 143.049 139.125 142.207 1.00 42.85  ? 260 ASP B CA  1 
ATOM   6953  C  C   . ASP D 1 267 ? 143.846 138.064 141.459 1.00 42.85  ? 260 ASP B C   1 
ATOM   6954  O  O   . ASP D 1 267 ? 145.080 138.094 141.506 1.00 42.85  ? 260 ASP B O   1 
ATOM   6955  C  CB  . ASP D 1 267 ? 143.169 138.881 143.712 1.00 42.85  ? 260 ASP B CB  1 
ATOM   6956  C  CG  . ASP D 1 267 ? 142.148 139.665 144.508 1.00 42.85  ? 260 ASP B CG  1 
ATOM   6957  O  OD1 . ASP D 1 267 ? 141.768 140.767 144.063 1.00 42.85  ? 260 ASP B OD1 1 
ATOM   6958  O  OD2 . ASP D 1 267 ? 141.722 139.176 145.575 1.00 42.85  ? 260 ASP B OD2 1 
ATOM   6959  N  N   . PHE D 1 268 ? 143.179 137.139 140.774 1.00 33.50  ? 261 PHE B N   1 
ATOM   6960  C  CA  . PHE D 1 268 ? 143.836 136.031 140.083 1.00 33.50  ? 261 PHE B CA  1 
ATOM   6961  C  C   . PHE D 1 268 ? 143.255 135.925 138.680 1.00 33.50  ? 261 PHE B C   1 
ATOM   6962  O  O   . PHE D 1 268 ? 142.167 135.352 138.500 1.00 33.50  ? 261 PHE B O   1 
ATOM   6963  C  CB  . PHE D 1 268 ? 143.655 134.729 140.856 1.00 33.50  ? 261 PHE B CB  1 
ATOM   6964  C  CG  . PHE D 1 268 ? 144.152 133.511 140.133 1.00 33.50  ? 261 PHE B CG  1 
ATOM   6965  C  CD1 . PHE D 1 268 ? 145.347 133.535 139.439 1.00 33.50  ? 261 PHE B CD1 1 
ATOM   6966  C  CD2 . PHE D 1 268 ? 143.430 132.333 140.166 1.00 33.50  ? 261 PHE B CD2 1 
ATOM   6967  C  CE1 . PHE D 1 268 ? 145.802 132.411 138.781 1.00 33.50  ? 261 PHE B CE1 1 
ATOM   6968  C  CE2 . PHE D 1 268 ? 143.882 131.209 139.511 1.00 33.50  ? 261 PHE B CE2 1 
ATOM   6969  C  CZ  . PHE D 1 268 ? 145.068 131.247 138.819 1.00 33.50  ? 261 PHE B CZ  1 
ATOM   6970  N  N   . PRO D 1 269 ? 143.936 136.471 137.667 1.00 29.98  ? 262 PRO B N   1 
ATOM   6971  C  CA  . PRO D 1 269 ? 143.381 136.419 136.303 1.00 29.98  ? 262 PRO B CA  1 
ATOM   6972  C  C   . PRO D 1 269 ? 143.120 135.009 135.803 1.00 29.98  ? 262 PRO B C   1 
ATOM   6973  O  O   . PRO D 1 269 ? 142.115 134.776 135.121 1.00 29.98  ? 262 PRO B O   1 
ATOM   6974  C  CB  . PRO D 1 269 ? 144.454 137.130 135.467 1.00 29.98  ? 262 PRO B CB  1 
ATOM   6975  C  CG  . PRO D 1 269 ? 145.195 137.980 136.444 1.00 29.98  ? 262 PRO B CG  1 
ATOM   6976  C  CD  . PRO D 1 269 ? 145.213 137.198 137.718 1.00 29.98  ? 262 PRO B CD  1 
ATOM   6977  N  N   . GLY D 1 270 ? 143.993 134.058 136.123 1.00 29.78  ? 263 GLY B N   1 
ATOM   6978  C  CA  . GLY D 1 270 ? 143.747 132.675 135.770 1.00 29.78  ? 263 GLY B CA  1 
ATOM   6979  C  C   . GLY D 1 270 ? 144.902 131.961 135.100 1.00 29.78  ? 263 GLY B C   1 
ATOM   6980  O  O   . GLY D 1 270 ? 144.787 130.777 134.774 1.00 29.78  ? 263 GLY B O   1 
ATOM   6981  N  N   . LEU D 1 271 ? 146.018 132.650 134.893 1.00 28.64  ? 264 LEU B N   1 
ATOM   6982  C  CA  . LEU D 1 271 ? 147.172 132.072 134.218 1.00 28.64  ? 264 LEU B CA  1 
ATOM   6983  C  C   . LEU D 1 271 ? 148.158 131.546 135.251 1.00 28.64  ? 264 LEU B C   1 
ATOM   6984  O  O   . LEU D 1 271 ? 148.523 132.262 136.188 1.00 28.64  ? 264 LEU B O   1 
ATOM   6985  C  CB  . LEU D 1 271 ? 147.855 133.104 133.320 1.00 28.64  ? 264 LEU B CB  1 
ATOM   6986  C  CG  . LEU D 1 271 ? 147.227 133.352 131.949 1.00 28.64  ? 264 LEU B CG  1 
ATOM   6987  C  CD1 . LEU D 1 271 ? 148.187 134.111 131.053 1.00 28.64  ? 264 LEU B CD1 1 
ATOM   6988  C  CD2 . LEU D 1 271 ? 146.814 132.045 131.303 1.00 28.64  ? 264 LEU B CD2 1 
ATOM   6989  N  N   . ILE D 1 272 ? 148.583 130.296 135.080 1.00 27.46  ? 265 ILE B N   1 
ATOM   6990  C  CA  . ILE D 1 272 ? 149.541 129.656 135.973 1.00 27.46  ? 265 ILE B CA  1 
ATOM   6991  C  C   . ILE D 1 272 ? 150.709 129.149 135.140 1.00 27.46  ? 265 ILE B C   1 
ATOM   6992  O  O   . ILE D 1 272 ? 150.509 128.409 134.172 1.00 27.46  ? 265 ILE B O   1 
ATOM   6993  C  CB  . ILE D 1 272 ? 148.896 128.507 136.768 1.00 27.46  ? 265 ILE B CB  1 
ATOM   6994  C  CG1 . ILE D 1 272 ? 147.852 129.055 137.737 1.00 27.46  ? 265 ILE B CG1 1 
ATOM   6995  C  CG2 . ILE D 1 272 ? 149.947 127.730 137.526 1.00 27.46  ? 265 ILE B CG2 1 
ATOM   6996  C  CD1 . ILE D 1 272 ? 147.288 128.014 138.665 1.00 27.46  ? 265 ILE B CD1 1 
ATOM   6997  N  N   . THR D 1 273 ? 151.922 129.531 135.519 1.00 28.20  ? 266 THR B N   1 
ATOM   6998  C  CA  . THR D 1 273 ? 153.117 129.178 134.767 1.00 28.20  ? 266 THR B CA  1 
ATOM   6999  C  C   . THR D 1 273 ? 153.923 128.144 135.536 1.00 28.20  ? 266 THR B C   1 
ATOM   7000  O  O   . THR D 1 273 ? 154.224 128.342 136.716 1.00 28.20  ? 266 THR B O   1 
ATOM   7001  C  CB  . THR D 1 273 ? 153.977 130.415 134.499 1.00 28.20  ? 266 THR B CB  1 
ATOM   7002  O  OG1 . THR D 1 273 ? 153.224 131.372 133.744 1.00 28.20  ? 266 THR B OG1 1 
ATOM   7003  C  CG2 . THR D 1 273 ? 155.226 130.036 133.722 1.00 28.20  ? 266 THR B CG2 1 
ATOM   7004  N  N   . LEU D 1 274 ? 154.274 127.046 134.872 1.00 28.77  ? 267 LEU B N   1 
ATOM   7005  C  CA  . LEU D 1 274 ? 155.171 126.049 135.439 1.00 28.77  ? 267 LEU B CA  1 
ATOM   7006  C  C   . LEU D 1 274 ? 156.450 126.015 134.618 1.00 28.77  ? 267 LEU B C   1 
ATOM   7007  O  O   . LEU D 1 274 ? 156.399 125.890 133.391 1.00 28.77  ? 267 LEU B O   1 
ATOM   7008  C  CB  . LEU D 1 274 ? 154.528 124.663 135.474 1.00 28.77  ? 267 LEU B CB  1 
ATOM   7009  C  CG  . LEU D 1 274 ? 153.731 124.333 136.734 1.00 28.77  ? 267 LEU B CG  1 
ATOM   7010  C  CD1 . LEU D 1 274 ? 152.409 125.074 136.754 1.00 28.77  ? 267 LEU B CD1 1 
ATOM   7011  C  CD2 . LEU D 1 274 ? 153.515 122.844 136.848 1.00 28.77  ? 267 LEU B CD2 1 
ATOM   7012  N  N   . THR D 1 275 ? 157.592 126.109 135.291 1.00 31.15  ? 268 THR B N   1 
ATOM   7013  C  CA  . THR D 1 275 ? 158.862 126.318 134.617 1.00 31.15  ? 268 THR B CA  1 
ATOM   7014  C  C   . THR D 1 275 ? 159.844 125.216 134.983 1.00 31.15  ? 268 THR B C   1 
ATOM   7015  O  O   . THR D 1 275 ? 159.931 124.808 136.146 1.00 31.15  ? 268 THR B O   1 
ATOM   7016  C  CB  . THR D 1 275 ? 159.443 127.684 134.984 1.00 31.15  ? 268 THR B CB  1 
ATOM   7017  O  OG1 . THR D 1 275 ? 158.442 128.693 134.804 1.00 31.15  ? 268 THR B OG1 1 
ATOM   7018  C  CG2 . THR D 1 275 ? 160.636 128.012 134.118 1.00 31.15  ? 268 THR B CG2 1 
ATOM   7019  N  N   . ILE D 1 276 ? 160.528 124.721 133.943 1.00 32.83  ? 269 ILE B N   1 
ATOM   7020  C  CA  . ILE D 1 276 ? 161.599 123.705 134.138 1.00 32.83  ? 269 ILE B CA  1 
ATOM   7021  C  C   . ILE D 1 276 ? 162.911 124.425 133.819 1.00 32.83  ? 269 ILE B C   1 
ATOM   7022  O  O   . ILE D 1 276 ? 162.982 125.085 132.764 1.00 32.83  ? 269 ILE B O   1 
ATOM   7023  C  CB  . ILE D 1 276 ? 161.362 122.465 133.253 1.00 32.83  ? 269 ILE B CB  1 
ATOM   7024  C  CG1 . ILE D 1 276 ? 162.474 121.425 133.414 1.00 32.83  ? 269 ILE B CG1 1 
ATOM   7025  C  CG2 . ILE D 1 276 ? 161.161 122.853 131.795 1.00 32.83  ? 269 ILE B CG2 1 
ATOM   7026  C  CD1 . ILE D 1 276 ? 162.427 120.675 134.725 1.00 32.83  ? 269 ILE B CD1 1 
ATOM   7027  N  N   . SER D 1 277 ? 163.896 124.333 134.706 1.00 33.60  ? 270 SER B N   1 
ATOM   7028  C  CA  . SER D 1 277 ? 165.157 125.043 134.559 1.00 33.60  ? 270 SER B CA  1 
ATOM   7029  C  C   . SER D 1 277 ? 166.322 124.085 134.743 1.00 33.60  ? 270 SER B C   1 
ATOM   7030  O  O   . SER D 1 277 ? 166.328 123.272 135.669 1.00 33.60  ? 270 SER B O   1 
ATOM   7031  C  CB  . SER D 1 277 ? 165.256 126.185 135.571 1.00 33.60  ? 270 SER B CB  1 
ATOM   7032  O  OG  . SER D 1 277 ? 166.508 126.834 135.487 1.00 33.60  ? 270 SER B OG  1 
ATOM   7033  N  N   . LEU D 1 278 ? 167.313 124.185 133.863 1.00 37.48  ? 271 LEU B N   1 
ATOM   7034  C  CA  . LEU D 1 278 ? 168.513 123.363 133.928 1.00 37.48  ? 271 LEU B CA  1 
ATOM   7035  C  C   . LEU D 1 278 ? 169.652 124.201 134.489 1.00 37.48  ? 271 LEU B C   1 
ATOM   7036  O  O   . LEU D 1 278 ? 169.941 125.284 133.972 1.00 37.48  ? 271 LEU B O   1 
ATOM   7037  C  CB  . LEU D 1 278 ? 168.877 122.819 132.546 1.00 37.48  ? 271 LEU B CB  1 
ATOM   7038  C  CG  . LEU D 1 278 ? 170.104 121.914 132.458 1.00 37.48  ? 271 LEU B CG  1 
ATOM   7039  C  CD1 . LEU D 1 278 ? 169.862 120.626 133.212 1.00 37.48  ? 271 LEU B CD1 1 
ATOM   7040  C  CD2 . LEU D 1 278 ? 170.456 121.621 131.013 1.00 37.48  ? 271 LEU B CD2 1 
ATOM   7041  N  N   . LEU D 1 279 ? 170.296 123.701 135.539 1.00 42.62  ? 272 LEU B N   1 
ATOM   7042  C  CA  . LEU D 1 279 ? 171.346 124.424 136.238 1.00 42.62  ? 272 LEU B CA  1 
ATOM   7043  C  C   . LEU D 1 279 ? 172.660 123.664 136.147 1.00 42.62  ? 272 LEU B C   1 
ATOM   7044  O  O   . LEU D 1 279 ? 172.696 122.439 136.303 1.00 42.62  ? 272 LEU B O   1 
ATOM   7045  C  CB  . LEU D 1 279 ? 170.984 124.642 137.708 1.00 42.62  ? 272 LEU B CB  1 
ATOM   7046  C  CG  . LEU D 1 279 ? 169.567 125.118 138.020 1.00 42.62  ? 272 LEU B CG  1 
ATOM   7047  C  CD1 . LEU D 1 279 ? 169.429 125.393 139.501 1.00 42.62  ? 272 LEU B CD1 1 
ATOM   7048  C  CD2 . LEU D 1 279 ? 169.232 126.357 137.219 1.00 42.62  ? 272 LEU B CD2 1 
ATOM   7049  N  N   . ASP D 1 280 ? 173.738 124.402 135.897 1.00 54.42  ? 273 ASP B N   1 
ATOM   7050  C  CA  . ASP D 1 280 ? 175.080 123.839 135.871 1.00 54.42  ? 273 ASP B CA  1 
ATOM   7051  C  C   . ASP D 1 280 ? 175.680 123.896 137.269 1.00 54.42  ? 273 ASP B C   1 
ATOM   7052  O  O   . ASP D 1 280 ? 175.703 124.959 137.899 1.00 54.42  ? 273 ASP B O   1 
ATOM   7053  C  CB  . ASP D 1 280 ? 175.962 124.599 134.882 1.00 54.42  ? 273 ASP B CB  1 
ATOM   7054  C  CG  . ASP D 1 280 ? 177.112 123.762 134.361 1.00 54.42  ? 273 ASP B CG  1 
ATOM   7055  O  OD1 . ASP D 1 280 ? 178.135 123.654 135.066 1.00 54.42  ? 273 ASP B OD1 1 
ATOM   7056  O  OD2 . ASP D 1 280 ? 176.995 123.217 133.244 1.00 54.42  ? 273 ASP B OD2 1 
ATOM   7057  N  N   . THR D 1 281 ? 176.158 122.755 137.753 1.00 59.75  ? 274 THR B N   1 
ATOM   7058  C  CA  . THR D 1 281 ? 176.757 122.642 139.077 1.00 59.75  ? 274 THR B CA  1 
ATOM   7059  C  C   . THR D 1 281 ? 178.100 121.934 138.996 1.00 59.75  ? 274 THR B C   1 
ATOM   7060  O  O   . THR D 1 281 ? 178.400 121.036 139.788 1.00 59.75  ? 274 THR B O   1 
ATOM   7061  C  CB  . THR D 1 281 ? 175.830 121.908 140.042 1.00 59.75  ? 274 THR B CB  1 
ATOM   7062  O  OG1 . THR D 1 281 ? 175.552 120.600 139.531 1.00 59.75  ? 274 THR B OG1 1 
ATOM   7063  C  CG2 . THR D 1 281 ? 174.524 122.668 140.213 1.00 59.75  ? 274 THR B CG2 1 
ATOM   7064  N  N   . SER D 1 282 ? 178.929 122.325 138.028 1.00 67.41  ? 275 SER B N   1 
ATOM   7065  C  CA  . SER D 1 282 ? 180.220 121.669 137.842 1.00 67.41  ? 275 SER B CA  1 
ATOM   7066  C  C   . SER D 1 282 ? 181.145 121.927 139.025 1.00 67.41  ? 275 SER B C   1 
ATOM   7067  O  O   . SER D 1 282 ? 181.730 120.996 139.590 1.00 67.41  ? 275 SER B O   1 
ATOM   7068  C  CB  . SER D 1 282 ? 180.863 122.145 136.538 1.00 67.41  ? 275 SER B CB  1 
ATOM   7069  O  OG  . SER D 1 282 ? 179.909 122.202 135.492 1.00 67.41  ? 275 SER B OG  1 
ATOM   7070  N  N   . ASN D 1 283 ? 181.294 123.191 139.413 1.00 73.66  ? 276 ASN B N   1 
ATOM   7071  C  CA  . ASN D 1 283 ? 182.200 123.570 140.487 1.00 73.66  ? 276 ASN B CA  1 
ATOM   7072  C  C   . ASN D 1 283 ? 181.402 123.680 141.780 1.00 73.66  ? 276 ASN B C   1 
ATOM   7073  O  O   . ASN D 1 283 ? 180.351 124.326 141.817 1.00 73.66  ? 276 ASN B O   1 
ATOM   7074  C  CB  . ASN D 1 283 ? 182.903 124.889 140.140 1.00 73.66  ? 276 ASN B CB  1 
ATOM   7075  C  CG  . ASN D 1 283 ? 183.737 125.466 141.288 1.00 73.66  ? 276 ASN B CG  1 
ATOM   7076  O  OD1 . ASN D 1 283 ? 183.414 125.335 142.467 1.00 73.66  ? 276 ASN B OD1 1 
ATOM   7077  N  ND2 . ASN D 1 283 ? 184.838 126.113 140.924 1.00 73.66  ? 276 ASN B ND2 1 
ATOM   7078  N  N   . LEU D 1 284 ? 181.910 123.047 142.841 1.00 78.25  ? 277 LEU B N   1 
ATOM   7079  C  CA  . LEU D 1 284 ? 181.208 123.038 144.120 1.00 78.25  ? 277 LEU B CA  1 
ATOM   7080  C  C   . LEU D 1 284 ? 181.339 124.358 144.869 1.00 78.25  ? 277 LEU B C   1 
ATOM   7081  O  O   . LEU D 1 284 ? 180.382 124.792 145.519 1.00 78.25  ? 277 LEU B O   1 
ATOM   7082  C  CB  . LEU D 1 284 ? 181.726 121.891 144.990 1.00 78.25  ? 277 LEU B CB  1 
ATOM   7083  C  CG  . LEU D 1 284 ? 181.554 120.484 144.416 1.00 78.25  ? 277 LEU B CG  1 
ATOM   7084  C  CD1 . LEU D 1 284 ? 181.943 119.433 145.443 1.00 78.25  ? 277 LEU B CD1 1 
ATOM   7085  C  CD2 . LEU D 1 284 ? 180.126 120.270 143.942 1.00 78.25  ? 277 LEU B CD2 1 
ATOM   7086  N  N   . GLU D 1 285 ? 182.507 125.003 144.801 1.00 78.47  ? 278 GLU B N   1 
ATOM   7087  C  CA  . GLU D 1 285 ? 182.700 126.267 145.506 1.00 78.47  ? 278 GLU B CA  1 
ATOM   7088  C  C   . GLU D 1 285 ? 181.756 127.340 144.981 1.00 78.47  ? 278 GLU B C   1 
ATOM   7089  O  O   . GLU D 1 285 ? 181.164 128.095 145.762 1.00 78.47  ? 278 GLU B O   1 
ATOM   7090  C  CB  . GLU D 1 285 ? 184.157 126.717 145.375 1.00 78.47  ? 278 GLU B CB  1 
ATOM   7091  C  CG  . GLU D 1 285 ? 185.161 125.824 146.090 1.00 78.47  ? 278 GLU B CG  1 
ATOM   7092  C  CD  . GLU D 1 285 ? 186.595 126.267 145.874 1.00 78.47  ? 278 GLU B CD  1 
ATOM   7093  O  OE1 . GLU D 1 285 ? 186.824 127.148 145.019 1.00 78.47  ? 278 GLU B OE1 1 
ATOM   7094  O  OE2 . GLU D 1 285 ? 187.494 125.738 146.562 1.00 78.47  ? 278 GLU B OE2 1 
ATOM   7095  N  N   . LEU D 1 286 ? 181.598 127.418 143.666 1.00 72.14  ? 279 LEU B N   1 
ATOM   7096  C  CA  . LEU D 1 286 ? 180.727 128.393 143.036 1.00 72.14  ? 279 LEU B CA  1 
ATOM   7097  C  C   . LEU D 1 286 ? 179.266 127.971 143.168 1.00 72.14  ? 279 LEU B C   1 
ATOM   7098  O  O   . LEU D 1 286 ? 178.964 126.787 143.331 1.00 72.14  ? 279 LEU B O   1 
ATOM   7099  C  CB  . LEU D 1 286 ? 181.104 128.543 141.565 1.00 72.14  ? 279 LEU B CB  1 
ATOM   7100  C  CG  . LEU D 1 286 ? 182.480 129.126 141.241 1.00 72.14  ? 279 LEU B CG  1 
ATOM   7101  C  CD1 . LEU D 1 286 ? 182.408 129.944 139.974 1.00 72.14  ? 279 LEU B CD1 1 
ATOM   7102  C  CD2 . LEU D 1 286 ? 183.004 129.985 142.384 1.00 72.14  ? 279 LEU B CD2 1 
ATOM   7103  N  N   . PRO D 1 287 ? 178.338 128.918 143.104 1.00 61.01  ? 280 PRO B N   1 
ATOM   7104  C  CA  . PRO D 1 287 ? 176.916 128.572 143.133 1.00 61.01  ? 280 PRO B CA  1 
ATOM   7105  C  C   . PRO D 1 287 ? 176.474 128.071 141.763 1.00 61.01  ? 280 PRO B C   1 
ATOM   7106  O  O   . PRO D 1 287 ? 177.232 128.070 140.797 1.00 61.01  ? 280 PRO B O   1 
ATOM   7107  C  CB  . PRO D 1 287 ? 176.222 129.886 143.507 1.00 61.01  ? 280 PRO B CB  1 
ATOM   7108  C  CG  . PRO D 1 287 ? 177.258 130.954 143.416 1.00 61.01  ? 280 PRO B CG  1 
ATOM   7109  C  CD  . PRO D 1 287 ? 178.552 130.366 142.963 1.00 61.01  ? 280 PRO B CD  1 
ATOM   7110  N  N   . GLU D 1 288 ? 175.220 127.638 141.697 1.00 55.51  ? 281 GLU B N   1 
ATOM   7111  C  CA  . GLU D 1 288 ? 174.678 127.110 140.456 1.00 55.51  ? 281 GLU B CA  1 
ATOM   7112  C  C   . GLU D 1 288 ? 174.475 128.228 139.437 1.00 55.51  ? 281 GLU B C   1 
ATOM   7113  O  O   . GLU D 1 288 ? 174.286 129.397 139.782 1.00 55.51  ? 281 GLU B O   1 
ATOM   7114  C  CB  . GLU D 1 288 ? 173.358 126.384 140.717 1.00 55.51  ? 281 GLU B CB  1 
ATOM   7115  C  CG  . GLU D 1 288 ? 172.197 127.296 141.072 1.00 55.51  ? 281 GLU B CG  1 
ATOM   7116  C  CD  . GLU D 1 288 ? 172.223 127.757 142.514 1.00 55.51  ? 281 GLU B CD  1 
ATOM   7117  O  OE1 . GLU D 1 288 ? 173.200 127.445 143.226 1.00 55.51  ? 281 GLU B OE1 1 
ATOM   7118  O  OE2 . GLU D 1 288 ? 171.263 128.433 142.938 1.00 55.51  ? 281 GLU B OE2 1 
ATOM   7119  N  N   . ALA D 1 289 ? 174.524 127.853 138.162 1.00 46.11  ? 282 ALA B N   1 
ATOM   7120  C  CA  . ALA D 1 289 ? 174.318 128.785 137.064 1.00 46.11  ? 282 ALA B CA  1 
ATOM   7121  C  C   . ALA D 1 289 ? 173.226 128.250 136.152 1.00 46.11  ? 282 ALA B C   1 
ATOM   7122  O  O   . ALA D 1 289 ? 173.269 127.085 135.746 1.00 46.11  ? 282 ALA B O   1 
ATOM   7123  C  CB  . ALA D 1 289 ? 175.609 129.004 136.274 1.00 46.11  ? 282 ALA B CB  1 
ATOM   7124  N  N   . VAL D 1 290 ? 172.254 129.099 135.834 1.00 38.73  ? 283 VAL B N   1 
ATOM   7125  C  CA  . VAL D 1 290 ? 171.134 128.704 134.988 1.00 38.73  ? 283 VAL B CA  1 
ATOM   7126  C  C   . VAL D 1 290 ? 171.576 128.737 133.531 1.00 38.73  ? 283 VAL B C   1 
ATOM   7127  O  O   . VAL D 1 290 ? 172.212 129.699 133.083 1.00 38.73  ? 283 VAL B O   1 
ATOM   7128  C  CB  . VAL D 1 290 ? 169.923 129.616 135.232 1.00 38.73  ? 283 VAL B CB  1 
ATOM   7129  C  CG1 . VAL D 1 290 ? 170.344 131.073 135.222 1.00 38.73  ? 283 VAL B CG1 1 
ATOM   7130  C  CG2 . VAL D 1 290 ? 168.840 129.359 134.201 1.00 38.73  ? 283 VAL B CG2 1 
ATOM   7131  N  N   . VAL D 1 291 ? 171.253 127.680 132.787 1.00 38.22  ? 284 VAL B N   1 
ATOM   7132  C  CA  . VAL D 1 291 ? 171.703 127.556 131.404 1.00 38.22  ? 284 VAL B CA  1 
ATOM   7133  C  C   . VAL D 1 291 ? 170.574 127.308 130.416 1.00 38.22  ? 284 VAL B C   1 
ATOM   7134  O  O   . VAL D 1 291 ? 170.775 127.484 129.201 1.00 38.22  ? 284 VAL B O   1 
ATOM   7135  C  CB  . VAL D 1 291 ? 172.770 126.444 131.287 1.00 38.22  ? 284 VAL B CB  1 
ATOM   7136  C  CG1 . VAL D 1 291 ? 172.112 125.077 131.236 1.00 38.22  ? 284 VAL B CG1 1 
ATOM   7137  C  CG2 . VAL D 1 291 ? 173.662 126.673 130.079 1.00 38.22  ? 284 VAL B CG2 1 
ATOM   7138  N  N   . PHE D 1 292 ? 169.380 126.914 130.853 1.00 37.44  ? 285 PHE B N   1 
ATOM   7139  C  CA  . PHE D 1 292 ? 168.268 126.674 129.944 1.00 37.44  ? 285 PHE B CA  1 
ATOM   7140  C  C   . PHE D 1 292 ? 166.984 126.729 130.755 1.00 37.44  ? 285 PHE B C   1 
ATOM   7141  O  O   . PHE D 1 292 ? 166.957 126.283 131.902 1.00 37.44  ? 285 PHE B O   1 
ATOM   7142  C  CB  . PHE D 1 292 ? 168.409 125.320 129.239 1.00 37.44  ? 285 PHE B CB  1 
ATOM   7143  C  CG  . PHE D 1 292 ? 167.161 124.855 128.543 1.00 37.44  ? 285 PHE B CG  1 
ATOM   7144  C  CD1 . PHE D 1 292 ? 166.828 125.345 127.293 1.00 37.44  ? 285 PHE B CD1 1 
ATOM   7145  C  CD2 . PHE D 1 292 ? 166.335 123.913 129.126 1.00 37.44  ? 285 PHE B CD2 1 
ATOM   7146  C  CE1 . PHE D 1 292 ? 165.688 124.915 126.647 1.00 37.44  ? 285 PHE B CE1 1 
ATOM   7147  C  CE2 . PHE D 1 292 ? 165.195 123.481 128.483 1.00 37.44  ? 285 PHE B CE2 1 
ATOM   7148  C  CZ  . PHE D 1 292 ? 164.871 123.983 127.242 1.00 37.44  ? 285 PHE B CZ  1 
ATOM   7149  N  N   . GLN D 1 293 ? 165.928 127.275 130.161 1.00 33.62  ? 286 GLN B N   1 
ATOM   7150  C  CA  . GLN D 1 293 ? 164.689 127.481 130.902 1.00 33.62  ? 286 GLN B CA  1 
ATOM   7151  C  C   . GLN D 1 293 ? 163.505 127.371 129.957 1.00 33.62  ? 286 GLN B C   1 
ATOM   7152  O  O   . GLN D 1 293 ? 163.327 128.226 129.085 1.00 33.62  ? 286 GLN B O   1 
ATOM   7153  C  CB  . GLN D 1 293 ? 164.701 128.842 131.599 1.00 33.62  ? 286 GLN B CB  1 
ATOM   7154  C  CG  . GLN D 1 293 ? 163.372 129.255 132.188 1.00 33.62  ? 286 GLN B CG  1 
ATOM   7155  C  CD  . GLN D 1 293 ? 163.533 130.067 133.456 1.00 33.62  ? 286 GLN B CD  1 
ATOM   7156  O  OE1 . GLN D 1 293 ? 164.604 130.085 134.060 1.00 33.62  ? 286 GLN B OE1 1 
ATOM   7157  N  NE2 . GLN D 1 293 ? 162.469 130.745 133.867 1.00 33.62  ? 286 GLN B NE2 1 
ATOM   7158  N  N   . ASP D 1 294 ? 162.699 126.329 130.133 1.00 35.72  ? 287 ASP B N   1 
ATOM   7159  C  CA  . ASP D 1 294 ? 161.475 126.151 129.372 1.00 35.72  ? 287 ASP B CA  1 
ATOM   7160  C  C   . ASP D 1 294 ? 160.288 126.309 130.311 1.00 35.72  ? 287 ASP B C   1 
ATOM   7161  O  O   . ASP D 1 294 ? 160.428 126.223 131.531 1.00 35.72  ? 287 ASP B O   1 
ATOM   7162  C  CB  . ASP D 1 294 ? 161.434 124.782 128.684 1.00 35.72  ? 287 ASP B CB  1 
ATOM   7163  C  CG  . ASP D 1 294 ? 160.397 124.714 127.583 1.00 35.72  ? 287 ASP B CG  1 
ATOM   7164  O  OD1 . ASP D 1 294 ? 159.733 125.740 127.329 1.00 35.72  ? 287 ASP B OD1 1 
ATOM   7165  O  OD2 . ASP D 1 294 ? 160.246 123.638 126.970 1.00 35.72  ? 287 ASP B OD2 1 
ATOM   7166  N  N   . SER D 1 295 ? 159.110 126.548 129.743 1.00 33.18  ? 288 SER B N   1 
ATOM   7167  C  CA  . SER D 1 295 ? 157.949 126.804 130.580 1.00 33.18  ? 288 SER B CA  1 
ATOM   7168  C  C   . SER D 1 295 ? 156.681 126.402 129.846 1.00 33.18  ? 288 SER B C   1 
ATOM   7169  O  O   . SER D 1 295 ? 156.666 126.242 128.624 1.00 33.18  ? 288 SER B O   1 
ATOM   7170  C  CB  . SER D 1 295 ? 157.876 128.276 130.999 1.00 33.18  ? 288 SER B CB  1 
ATOM   7171  O  OG  . SER D 1 295 ? 157.693 129.115 129.874 1.00 33.18  ? 288 SER B OG  1 
ATOM   7172  N  N   . VAL D 1 296 ? 155.612 126.236 130.621 1.00 28.96  ? 289 VAL B N   1 
ATOM   7173  C  CA  . VAL D 1 296 ? 154.284 125.971 130.088 1.00 28.96  ? 289 VAL B CA  1 
ATOM   7174  C  C   . VAL D 1 296 ? 153.285 126.831 130.849 1.00 28.96  ? 289 VAL B C   1 
ATOM   7175  O  O   . VAL D 1 296 ? 153.480 127.157 132.026 1.00 28.96  ? 289 VAL B O   1 
ATOM   7176  C  CB  . VAL D 1 296 ? 153.915 124.472 130.165 1.00 28.96  ? 289 VAL B CB  1 
ATOM   7177  C  CG1 . VAL D 1 296 ? 153.449 124.099 131.554 1.00 28.96  ? 289 VAL B CG1 1 
ATOM   7178  C  CG2 . VAL D 1 296 ? 152.852 124.133 129.134 1.00 28.96  ? 289 VAL B CG2 1 
ATOM   7179  N  N   . VAL D 1 297 ? 152.219 127.221 130.155 1.00 29.47  ? 290 VAL B N   1 
ATOM   7180  C  CA  . VAL D 1 297 ? 151.209 128.131 130.680 1.00 29.47  ? 290 VAL B CA  1 
ATOM   7181  C  C   . VAL D 1 297 ? 149.868 127.416 130.686 1.00 29.47  ? 290 VAL B C   1 
ATOM   7182  O  O   . VAL D 1 297 ? 149.443 126.875 129.659 1.00 29.47  ? 290 VAL B O   1 
ATOM   7183  C  CB  . VAL D 1 297 ? 151.129 129.427 129.854 1.00 29.47  ? 290 VAL B CB  1 
ATOM   7184  C  CG1 . VAL D 1 297 ? 150.156 130.398 130.490 1.00 29.47  ? 290 VAL B CG1 1 
ATOM   7185  C  CG2 . VAL D 1 297 ? 152.501 130.056 129.728 1.00 29.47  ? 290 VAL B CG2 1 
ATOM   7186  N  N   . PHE D 1 298 ? 149.203 127.427 131.836 1.00 28.45  ? 291 PHE B N   1 
ATOM   7187  C  CA  . PHE D 1 298 ? 147.910 126.797 132.030 1.00 28.45  ? 291 PHE B CA  1 
ATOM   7188  C  C   . PHE D 1 298 ? 146.868 127.861 132.334 1.00 28.45  ? 291 PHE B C   1 
ATOM   7189  O  O   . PHE D 1 298 ? 147.176 128.901 132.923 1.00 28.45  ? 291 PHE B O   1 
ATOM   7190  C  CB  . PHE D 1 298 ? 147.938 125.812 133.194 1.00 28.45  ? 291 PHE B CB  1 
ATOM   7191  C  CG  . PHE D 1 298 ? 148.835 124.628 132.989 1.00 28.45  ? 291 PHE B CG  1 
ATOM   7192  C  CD1 . PHE D 1 298 ? 148.556 123.688 132.018 1.00 28.45  ? 291 PHE B CD1 1 
ATOM   7193  C  CD2 . PHE D 1 298 ? 149.919 124.420 133.818 1.00 28.45  ? 291 PHE B CD2 1 
ATOM   7194  C  CE1 . PHE D 1 298 ? 149.367 122.585 131.850 1.00 28.45  ? 291 PHE B CE1 1 
ATOM   7195  C  CE2 . PHE D 1 298 ? 150.731 123.320 133.654 1.00 28.45  ? 291 PHE B CE2 1 
ATOM   7196  C  CZ  . PHE D 1 298 ? 150.454 122.403 132.669 1.00 28.45  ? 291 PHE B CZ  1 
ATOM   7197  N  N   . ARG D 1 299 ? 145.623 127.586 131.955 1.00 28.02  ? 292 ARG B N   1 
ATOM   7198  C  CA  . ARG D 1 299 ? 144.501 128.421 132.354 1.00 28.02  ? 292 ARG B CA  1 
ATOM   7199  C  C   . ARG D 1 299 ? 143.559 127.629 133.247 1.00 28.02  ? 292 ARG B C   1 
ATOM   7200  O  O   . ARG D 1 299 ? 143.242 126.472 132.959 1.00 28.02  ? 292 ARG B O   1 
ATOM   7201  C  CB  . ARG D 1 299 ? 143.733 128.959 131.150 1.00 28.02  ? 292 ARG B CB  1 
ATOM   7202  C  CG  . ARG D 1 299 ? 142.530 129.804 131.539 1.00 28.02  ? 292 ARG B CG  1 
ATOM   7203  C  CD  . ARG D 1 299 ? 141.980 130.571 130.356 1.00 28.02  ? 292 ARG B CD  1 
ATOM   7204  N  NE  . ARG D 1 299 ? 142.792 131.742 130.051 1.00 28.02  ? 292 ARG B NE  1 
ATOM   7205  C  CZ  . ARG D 1 299 ? 142.808 132.854 130.773 1.00 28.02  ? 292 ARG B CZ  1 
ATOM   7206  N  NH1 . ARG D 1 299 ? 142.052 132.991 131.848 1.00 28.02  ? 292 ARG B NH1 1 
ATOM   7207  N  NH2 . ARG D 1 299 ? 143.601 133.855 130.404 1.00 28.02  ? 292 ARG B NH2 1 
ATOM   7208  N  N   . VAL D 1 300 ? 143.127 128.252 134.338 1.00 24.71  ? 293 VAL B N   1 
ATOM   7209  C  CA  . VAL D 1 300 ? 142.167 127.632 135.242 1.00 24.71  ? 293 VAL B CA  1 
ATOM   7210  C  C   . VAL D 1 300 ? 140.784 127.697 134.610 1.00 24.71  ? 293 VAL B C   1 
ATOM   7211  O  O   . VAL D 1 300 ? 140.336 128.766 134.178 1.00 24.71  ? 293 VAL B O   1 
ATOM   7212  C  CB  . VAL D 1 300 ? 142.188 128.325 136.612 1.00 24.71  ? 293 VAL B CB  1 
ATOM   7213  C  CG1 . VAL D 1 300 ? 141.159 127.706 137.530 1.00 24.71  ? 293 VAL B CG1 1 
ATOM   7214  C  CG2 . VAL D 1 300 ? 143.571 128.232 137.227 1.00 24.71  ? 293 VAL B CG2 1 
ATOM   7215  N  N   . ALA D 1 301 ? 140.107 126.556 134.552 1.00 23.21  ? 294 ALA B N   1 
ATOM   7216  C  CA  . ALA D 1 301 ? 138.823 126.483 133.873 1.00 23.21  ? 294 ALA B CA  1 
ATOM   7217  C  C   . ALA D 1 301 ? 137.797 127.363 134.578 1.00 23.21  ? 294 ALA B C   1 
ATOM   7218  O  O   . ALA D 1 301 ? 137.624 127.249 135.798 1.00 23.21  ? 294 ALA B O   1 
ATOM   7219  C  CB  . ALA D 1 301 ? 138.331 125.039 133.823 1.00 23.21  ? 294 ALA B CB  1 
ATOM   7220  N  N   . PRO D 1 302 ? 137.104 128.240 133.861 1.00 24.16  ? 295 PRO B N   1 
ATOM   7221  C  CA  . PRO D 1 302 ? 136.129 129.121 134.504 1.00 24.16  ? 295 PRO B CA  1 
ATOM   7222  C  C   . PRO D 1 302 ? 134.821 128.404 134.795 1.00 24.16  ? 295 PRO B C   1 
ATOM   7223  O  O   . PRO D 1 302 ? 134.529 127.333 134.263 1.00 24.16  ? 295 PRO B O   1 
ATOM   7224  C  CB  . PRO D 1 302 ? 135.926 130.226 133.464 1.00 24.16  ? 295 PRO B CB  1 
ATOM   7225  C  CG  . PRO D 1 302 ? 136.131 129.534 132.171 1.00 24.16  ? 295 PRO B CG  1 
ATOM   7226  C  CD  . PRO D 1 302 ? 137.183 128.477 132.411 1.00 24.16  ? 295 PRO B CD  1 
ATOM   7227  N  N   . TRP D 1 303 ? 134.025 129.030 135.657 1.00 25.34  ? 296 TRP B N   1 
ATOM   7228  C  CA  . TRP D 1 303 ? 132.707 128.511 135.999 1.00 25.34  ? 296 TRP B CA  1 
ATOM   7229  C  C   . TRP D 1 303 ? 131.706 128.939 134.934 1.00 25.34  ? 296 TRP B C   1 
ATOM   7230  O  O   . TRP D 1 303 ? 131.487 130.136 134.726 1.00 25.34  ? 296 TRP B O   1 
ATOM   7231  C  CB  . TRP D 1 303 ? 132.281 129.009 137.375 1.00 25.34  ? 296 TRP B CB  1 
ATOM   7232  C  CG  . TRP D 1 303 ? 131.019 128.394 137.874 1.00 25.34  ? 296 TRP B CG  1 
ATOM   7233  C  CD1 . TRP D 1 303 ? 130.839 127.105 138.265 1.00 25.34  ? 296 TRP B CD1 1 
ATOM   7234  C  CD2 . TRP D 1 303 ? 129.758 129.047 138.048 1.00 25.34  ? 296 TRP B CD2 1 
ATOM   7235  N  NE1 . TRP D 1 303 ? 129.543 126.909 138.669 1.00 25.34  ? 296 TRP B NE1 1 
ATOM   7236  C  CE2 . TRP D 1 303 ? 128.859 128.088 138.546 1.00 25.34  ? 296 TRP B CE2 1 
ATOM   7237  C  CE3 . TRP D 1 303 ? 129.303 130.349 137.831 1.00 25.34  ? 296 TRP B CE3 1 
ATOM   7238  C  CZ2 . TRP D 1 303 ? 127.533 128.387 138.829 1.00 25.34  ? 296 TRP B CZ2 1 
ATOM   7239  C  CZ3 . TRP D 1 303 ? 127.989 130.645 138.115 1.00 25.34  ? 296 TRP B CZ3 1 
ATOM   7240  C  CH2 . TRP D 1 303 ? 127.117 129.668 138.607 1.00 25.34  ? 296 TRP B CH2 1 
ATOM   7241  N  N   . ILE D 1 304 ? 131.096 127.966 134.266 1.00 24.36  ? 297 ILE B N   1 
ATOM   7242  C  CA  . ILE D 1 304 ? 130.221 128.211 133.128 1.00 24.36  ? 297 ILE B CA  1 
ATOM   7243  C  C   . ILE D 1 304 ? 128.821 127.735 133.486 1.00 24.36  ? 297 ILE B C   1 
ATOM   7244  O  O   . ILE D 1 304 ? 128.644 126.599 133.940 1.00 24.36  ? 297 ILE B O   1 
ATOM   7245  C  CB  . ILE D 1 304 ? 130.732 127.501 131.864 1.00 24.36  ? 297 ILE B CB  1 
ATOM   7246  C  CG1 . ILE D 1 304 ? 132.247 127.647 131.758 1.00 24.36  ? 297 ILE B CG1 1 
ATOM   7247  C  CG2 . ILE D 1 304 ? 130.070 128.075 130.632 1.00 24.36  ? 297 ILE B CG2 1 
ATOM   7248  C  CD1 . ILE D 1 304 ? 132.849 126.885 130.612 1.00 24.36  ? 297 ILE B CD1 1 
ATOM   7249  N  N   . MET D 1 305 ? 127.835 128.599 133.281 1.00 27.79  ? 298 MET B N   1 
ATOM   7250  C  CA  . MET D 1 305 ? 126.451 128.290 133.597 1.00 27.79  ? 298 MET B CA  1 
ATOM   7251  C  C   . MET D 1 305 ? 125.777 127.589 132.422 1.00 27.79  ? 298 MET B C   1 
ATOM   7252  O  O   . MET D 1 305 ? 126.361 127.406 131.353 1.00 27.79  ? 298 MET B O   1 
ATOM   7253  C  CB  . MET D 1 305 ? 125.696 129.564 133.957 1.00 27.79  ? 298 MET B CB  1 
ATOM   7254  C  CG  . MET D 1 305 ? 126.122 130.192 135.263 1.00 27.79  ? 298 MET B CG  1 
ATOM   7255  S  SD  . MET D 1 305 ? 124.826 131.193 136.007 1.00 27.79  ? 298 MET B SD  1 
ATOM   7256  C  CE  . MET D 1 305 ? 123.434 130.080 135.882 1.00 27.79  ? 298 MET B CE  1 
ATOM   7257  N  N   . THR D 1 306 ? 124.524 127.188 132.633 1.00 26.99  ? 299 THR B N   1 
ATOM   7258  C  CA  . THR D 1 306 ? 123.727 126.553 131.593 1.00 26.99  ? 299 THR B CA  1 
ATOM   7259  C  C   . THR D 1 306 ? 122.386 127.270 131.484 1.00 26.99  ? 299 THR B C   1 
ATOM   7260  O  O   . THR D 1 306 ? 121.680 127.422 132.494 1.00 26.99  ? 299 THR B O   1 
ATOM   7261  C  CB  . THR D 1 306 ? 123.508 125.063 131.882 1.00 26.99  ? 299 THR B CB  1 
ATOM   7262  O  OG1 . THR D 1 306 ? 122.702 124.911 133.055 1.00 26.99  ? 299 THR B OG1 1 
ATOM   7263  C  CG2 . THR D 1 306 ? 124.832 124.355 132.084 1.00 26.99  ? 299 THR B CG2 1 
ATOM   7264  N  N   . PRO D 1 307 ? 121.998 127.715 130.292 1.00 29.14  ? 300 PRO B N   1 
ATOM   7265  C  CA  . PRO D 1 307 ? 120.706 128.395 130.137 1.00 29.14  ? 300 PRO B CA  1 
ATOM   7266  C  C   . PRO D 1 307 ? 119.537 127.428 130.137 1.00 29.14  ? 300 PRO B C   1 
ATOM   7267  O  O   . PRO D 1 307 ? 119.713 126.234 130.393 1.00 29.14  ? 300 PRO B O   1 
ATOM   7268  C  CB  . PRO D 1 307 ? 120.850 129.103 128.786 1.00 29.14  ? 300 PRO B CB  1 
ATOM   7269  C  CG  . PRO D 1 307 ? 121.783 128.236 128.027 1.00 29.14  ? 300 PRO B CG  1 
ATOM   7270  C  CD  . PRO D 1 307 ? 122.751 127.666 129.029 1.00 29.14  ? 300 PRO B CD  1 
ATOM   7271  N  N   . ASN D 1 308 ? 118.337 127.931 129.851 1.00 33.88  ? 301 ASN B N   1 
ATOM   7272  C  CA  . ASN D 1 308 ? 117.132 127.115 129.911 1.00 33.88  ? 301 ASN B CA  1 
ATOM   7273  C  C   . ASN D 1 308 ? 116.878 126.302 128.649 1.00 33.88  ? 301 ASN B C   1 
ATOM   7274  O  O   . ASN D 1 308 ? 115.955 125.481 128.642 1.00 33.88  ? 301 ASN B O   1 
ATOM   7275  C  CB  . ASN D 1 308 ? 115.916 127.998 130.193 1.00 33.88  ? 301 ASN B CB  1 
ATOM   7276  C  CG  . ASN D 1 308 ? 116.019 128.721 131.516 1.00 33.88  ? 301 ASN B CG  1 
ATOM   7277  O  OD1 . ASN D 1 308 ? 116.902 129.554 131.715 1.00 33.88  ? 301 ASN B OD1 1 
ATOM   7278  N  ND2 . ASN D 1 308 ? 115.115 128.404 132.435 1.00 33.88  ? 301 ASN B ND2 1 
ATOM   7279  N  N   . THR D 1 309 ? 117.658 126.496 127.590 1.00 34.81  ? 302 THR B N   1 
ATOM   7280  C  CA  . THR D 1 309 ? 117.429 125.783 126.342 1.00 34.81  ? 302 THR B CA  1 
ATOM   7281  C  C   . THR D 1 309 ? 118.155 124.446 126.271 1.00 34.81  ? 302 THR B C   1 
ATOM   7282  O  O   . THR D 1 309 ? 117.974 123.714 125.292 1.00 34.81  ? 302 THR B O   1 
ATOM   7283  C  CB  . THR D 1 309 ? 117.842 126.650 125.152 1.00 34.81  ? 302 THR B CB  1 
ATOM   7284  O  OG1 . THR D 1 309 ? 119.221 127.012 125.282 1.00 34.81  ? 302 THR B OG1 1 
ATOM   7285  C  CG2 . THR D 1 309 ? 116.997 127.907 125.102 1.00 34.81  ? 302 THR B CG2 1 
ATOM   7286  N  N   . GLN D 1 310 ? 118.966 124.105 127.278 1.00 32.01  ? 303 GLN B N   1 
ATOM   7287  C  CA  . GLN D 1 310 ? 119.666 122.830 127.290 1.00 32.01  ? 303 GLN B CA  1 
ATOM   7288  C  C   . GLN D 1 310 ? 118.767 121.727 127.841 1.00 32.01  ? 303 GLN B C   1 
ATOM   7289  O  O   . GLN D 1 310 ? 117.924 121.981 128.708 1.00 32.01  ? 303 GLN B O   1 
ATOM   7290  C  CB  . GLN D 1 310 ? 120.929 122.928 128.137 1.00 32.01  ? 303 GLN B CB  1 
ATOM   7291  C  CG  . GLN D 1 310 ? 121.927 123.936 127.619 1.00 32.01  ? 303 GLN B CG  1 
ATOM   7292  C  CD  . GLN D 1 310 ? 122.805 123.368 126.533 1.00 32.01  ? 303 GLN B CD  1 
ATOM   7293  O  OE1 . GLN D 1 310 ? 122.660 123.707 125.360 1.00 32.01  ? 303 GLN B OE1 1 
ATOM   7294  N  NE2 . GLN D 1 310 ? 123.732 122.500 126.917 1.00 32.01  ? 303 GLN B NE2 1 
ATOM   7295  N  N   . PRO D 1 311 ? 118.915 120.501 127.349 1.00 35.02  ? 304 PRO B N   1 
ATOM   7296  C  CA  . PRO D 1 311 ? 118.111 119.387 127.865 1.00 35.02  ? 304 PRO B CA  1 
ATOM   7297  C  C   . PRO D 1 311 ? 118.415 119.125 129.329 1.00 35.02  ? 304 PRO B C   1 
ATOM   7298  O  O   . PRO D 1 311 ? 119.580 119.177 129.750 1.00 35.02  ? 304 PRO B O   1 
ATOM   7299  C  CB  . PRO D 1 311 ? 118.542 118.204 126.985 1.00 35.02  ? 304 PRO B CB  1 
ATOM   7300  C  CG  . PRO D 1 311 ? 119.113 118.835 125.755 1.00 35.02  ? 304 PRO B CG  1 
ATOM   7301  C  CD  . PRO D 1 311 ? 119.777 120.085 126.232 1.00 35.02  ? 304 PRO B CD  1 
ATOM   7302  N  N   . PRO D 1 312 ? 117.398 118.840 130.134 1.00 37.48  ? 305 PRO B N   1 
ATOM   7303  C  CA  . PRO D 1 312 ? 117.624 118.574 131.556 1.00 37.48  ? 305 PRO B CA  1 
ATOM   7304  C  C   . PRO D 1 312 ? 118.226 117.196 131.786 1.00 37.48  ? 305 PRO B C   1 
ATOM   7305  O  O   . PRO D 1 312 ? 118.187 116.316 130.926 1.00 37.48  ? 305 PRO B O   1 
ATOM   7306  C  CB  . PRO D 1 312 ? 116.215 118.659 132.158 1.00 37.48  ? 305 PRO B CB  1 
ATOM   7307  C  CG  . PRO D 1 312 ? 115.406 119.391 131.130 1.00 37.48  ? 305 PRO B CG  1 
ATOM   7308  C  CD  . PRO D 1 312 ? 115.966 118.940 129.828 1.00 37.48  ? 305 PRO B CD  1 
ATOM   7309  N  N   . GLN D 1 313 ? 118.798 117.024 132.978 1.00 38.53  ? 306 GLN B N   1 
ATOM   7310  C  CA  . GLN D 1 313 ? 119.351 115.733 133.365 1.00 38.53  ? 306 GLN B CA  1 
ATOM   7311  C  C   . GLN D 1 313 ? 118.921 115.329 134.769 1.00 38.53  ? 306 GLN B C   1 
ATOM   7312  O  O   . GLN D 1 313 ? 118.865 114.137 135.085 1.00 38.53  ? 306 GLN B O   1 
ATOM   7313  C  CB  . GLN D 1 313 ? 120.877 115.757 133.271 1.00 38.53  ? 306 GLN B CB  1 
ATOM   7314  C  CG  . GLN D 1 313 ? 121.415 115.411 131.896 1.00 38.53  ? 306 GLN B CG  1 
ATOM   7315  C  CD  . GLN D 1 313 ? 122.926 115.441 131.838 1.00 38.53  ? 306 GLN B CD  1 
ATOM   7316  O  OE1 . GLN D 1 313 ? 123.587 115.836 132.796 1.00 38.53  ? 306 GLN B OE1 1 
ATOM   7317  N  NE2 . GLN D 1 313 ? 123.482 115.017 130.711 1.00 38.53  ? 306 GLN B NE2 1 
ATOM   7318  N  N   . GLU D 1 314 ? 118.616 116.306 135.619 1.00 43.38  ? 307 GLU B N   1 
ATOM   7319  C  CA  . GLU D 1 314 ? 118.299 116.030 137.013 1.00 43.38  ? 307 GLU B CA  1 
ATOM   7320  C  C   . GLU D 1 314 ? 117.545 117.218 137.590 1.00 43.38  ? 307 GLU B C   1 
ATOM   7321  O  O   . GLU D 1 314 ? 117.901 118.368 137.324 1.00 43.38  ? 307 GLU B O   1 
ATOM   7322  C  CB  . GLU D 1 314 ? 119.574 115.754 137.818 1.00 43.38  ? 307 GLU B CB  1 
ATOM   7323  C  CG  . GLU D 1 314 ? 119.378 115.677 139.320 1.00 43.38  ? 307 GLU B CG  1 
ATOM   7324  C  CD  . GLU D 1 314 ? 120.636 115.238 140.044 1.00 43.38  ? 307 GLU B CD  1 
ATOM   7325  O  OE1 . GLU D 1 314 ? 121.637 114.930 139.364 1.00 43.38  ? 307 GLU B OE1 1 
ATOM   7326  O  OE2 . GLU D 1 314 ? 120.626 115.203 141.291 1.00 43.38  ? 307 GLU B OE2 1 
ATOM   7327  N  N   . VAL D 1 315 ? 116.511 116.935 138.378 1.00 44.97  ? 308 VAL B N   1 
ATOM   7328  C  CA  . VAL D 1 315 ? 115.638 117.960 138.938 1.00 44.97  ? 308 VAL B CA  1 
ATOM   7329  C  C   . VAL D 1 315 ? 115.639 117.829 140.453 1.00 44.97  ? 308 VAL B C   1 
ATOM   7330  O  O   . VAL D 1 315 ? 115.473 116.726 140.986 1.00 44.97  ? 308 VAL B O   1 
ATOM   7331  C  CB  . VAL D 1 315 ? 114.206 117.846 138.387 1.00 44.97  ? 308 VAL B CB  1 
ATOM   7332  C  CG1 . VAL D 1 315 ? 113.345 118.978 138.913 1.00 44.97  ? 308 VAL B CG1 1 
ATOM   7333  C  CG2 . VAL D 1 315 ? 114.223 117.853 136.872 1.00 44.97  ? 308 VAL B CG2 1 
ATOM   7334  N  N   . TYR D 1 316 ? 115.820 118.952 141.142 1.00 49.21  ? 309 TYR B N   1 
ATOM   7335  C  CA  . TYR D 1 316 ? 115.750 119.018 142.595 1.00 49.21  ? 309 TYR B CA  1 
ATOM   7336  C  C   . TYR D 1 316 ? 114.441 119.667 143.014 1.00 49.21  ? 309 TYR B C   1 
ATOM   7337  O  O   . TYR D 1 316 ? 113.877 120.481 142.277 1.00 49.21  ? 309 TYR B O   1 
ATOM   7338  C  CB  . TYR D 1 316 ? 116.927 119.806 143.175 1.00 49.21  ? 309 TYR B CB  1 
ATOM   7339  C  CG  . TYR D 1 316 ? 118.282 119.245 142.822 1.00 49.21  ? 309 TYR B CG  1 
ATOM   7340  C  CD1 . TYR D 1 316 ? 118.967 119.686 141.703 1.00 49.21  ? 309 TYR B CD1 1 
ATOM   7341  C  CD2 . TYR D 1 316 ? 118.873 118.270 143.608 1.00 49.21  ? 309 TYR B CD2 1 
ATOM   7342  C  CE1 . TYR D 1 316 ? 120.204 119.174 141.377 1.00 49.21  ? 309 TYR B CE1 1 
ATOM   7343  C  CE2 . TYR D 1 316 ? 120.109 117.751 143.291 1.00 49.21  ? 309 TYR B CE2 1 
ATOM   7344  C  CZ  . TYR D 1 316 ? 120.769 118.207 142.175 1.00 49.21  ? 309 TYR B CZ  1 
ATOM   7345  O  OH  . TYR D 1 316 ? 122.002 117.690 141.854 1.00 49.21  ? 309 TYR B OH  1 
ATOM   7346  N  N   . ALA D 1 317 ? 113.956 119.304 144.199 1.00 64.24  ? 310 ALA B N   1 
ATOM   7347  C  CA  . ALA D 1 317 ? 112.711 119.844 144.724 1.00 64.24  ? 310 ALA B CA  1 
ATOM   7348  C  C   . ALA D 1 317 ? 112.761 119.819 146.245 1.00 64.24  ? 310 ALA B C   1 
ATOM   7349  O  O   . ALA D 1 317 ? 113.802 119.554 146.852 1.00 64.24  ? 310 ALA B O   1 
ATOM   7350  C  CB  . ALA D 1 317 ? 111.502 119.064 144.198 1.00 64.24  ? 310 ALA B CB  1 
ATOM   7351  N  N   . CYS D 1 318 ? 111.618 120.101 146.865 1.00 81.01  ? 311 CYS B N   1 
ATOM   7352  C  CA  . CYS D 1 318 ? 111.498 120.140 148.314 1.00 81.01  ? 311 CYS B CA  1 
ATOM   7353  C  C   . CYS D 1 318 ? 110.133 119.625 148.738 1.00 81.01  ? 311 CYS B C   1 
ATOM   7354  O  O   . CYS D 1 318 ? 109.190 119.607 147.944 1.00 81.01  ? 311 CYS B O   1 
ATOM   7355  C  CB  . CYS D 1 318 ? 111.699 121.557 148.848 1.00 81.01  ? 311 CYS B CB  1 
ATOM   7356  S  SG  . CYS D 1 318 ? 111.112 121.783 150.536 1.00 81.01  ? 311 CYS B SG  1 
ATOM   7357  N  N   . SER D 1 319 ? 110.040 119.198 149.996 1.00 85.33  ? 312 SER B N   1 
ATOM   7358  C  CA  . SER D 1 319 ? 108.790 118.747 150.597 1.00 85.33  ? 312 SER B CA  1 
ATOM   7359  C  C   . SER D 1 319 ? 108.705 119.312 152.007 1.00 85.33  ? 312 SER B C   1 
ATOM   7360  O  O   . SER D 1 319 ? 109.585 119.051 152.835 1.00 85.33  ? 312 SER B O   1 
ATOM   7361  C  CB  . SER D 1 319 ? 108.712 117.220 150.621 1.00 85.33  ? 312 SER B CB  1 
ATOM   7362  O  OG  . SER D 1 319 ? 107.563 116.779 151.321 1.00 85.33  ? 312 SER B OG  1 
ATOM   7363  N  N   . ILE D 1 320 ? 107.656 120.084 152.304 1.00 87.29  ? 313 ILE B N   1 
ATOM   7364  C  CA  . ILE D 1 320 ? 107.545 120.703 153.663 1.00 87.29  ? 313 ILE B CA  1 
ATOM   7365  C  C   . ILE D 1 320 ? 106.209 120.306 154.312 1.00 87.29  ? 313 ILE B C   1 
ATOM   7366  O  O   . ILE D 1 320 ? 106.260 119.686 155.395 1.00 87.29  ? 313 ILE B O   1 
ATOM   7367  C  CB  . ILE D 1 320 ? 107.787 122.231 153.639 1.00 87.29  ? 313 ILE B CB  1 
ATOM   7368  C  CG1 . ILE D 1 320 ? 107.811 122.820 155.053 1.00 87.29  ? 313 ILE B CG1 1 
ATOM   7369  C  CG2 . ILE D 1 320 ? 106.795 122.965 152.749 1.00 87.29  ? 313 ILE B CG2 1 
ATOM   7370  C  CD1 . ILE D 1 320 ? 107.889 124.328 155.083 1.00 87.29  ? 313 ILE B CD1 1 
ATOM   7371  N  N   . PHE D 1 321 ? 105.073 120.618 153.678 1.00 95.80  ? 314 PHE B N   1 
ATOM   7372  C  CA  . PHE D 1 321 ? 103.766 120.298 154.232 1.00 95.80  ? 314 PHE B CA  1 
ATOM   7373  C  C   . PHE D 1 321 ? 102.733 120.721 153.197 1.00 95.80  ? 314 PHE B C   1 
ATOM   7374  O  O   . PHE D 1 321 ? 102.955 121.681 152.453 1.00 95.80  ? 314 PHE B O   1 
ATOM   7375  C  CB  . PHE D 1 321 ? 103.541 121.011 155.574 1.00 95.80  ? 314 PHE B CB  1 
ATOM   7376  C  CG  . PHE D 1 321 ? 102.616 120.282 156.511 1.00 95.80  ? 314 PHE B CG  1 
ATOM   7377  C  CD1 . PHE D 1 321 ? 101.251 120.247 156.295 1.00 95.80  ? 314 PHE B CD1 1 
ATOM   7378  C  CD2 . PHE D 1 321 ? 103.127 119.623 157.619 1.00 95.80  ? 314 PHE B CD2 1 
ATOM   7379  C  CE1 . PHE D 1 321 ? 100.412 119.574 157.162 1.00 95.80  ? 314 PHE B CE1 1 
ATOM   7380  C  CE2 . PHE D 1 321 ? 102.294 118.948 158.489 1.00 95.80  ? 314 PHE B CE2 1 
ATOM   7381  C  CZ  . PHE D 1 321 ? 100.934 118.923 158.261 1.00 95.80  ? 314 PHE B CZ  1 
ATOM   7382  N  N   . GLU D 1 322 ? 101.595 120.023 153.182 1.00 98.38  ? 315 GLU B N   1 
ATOM   7383  C  CA  . GLU D 1 322 ? 100.664 120.027 152.052 1.00 98.38  ? 315 GLU B CA  1 
ATOM   7384  C  C   . GLU D 1 322 ? 101.418 120.119 150.728 1.00 98.38  ? 315 GLU B C   1 
ATOM   7385  O  O   . GLU D 1 322 ? 101.198 121.051 149.949 1.00 98.38  ? 315 GLU B O   1 
ATOM   7386  C  CB  . GLU D 1 322 ? 99.589  121.137 152.097 1.00 98.38  ? 315 GLU B CB  1 
ATOM   7387  C  CG  . GLU D 1 322 ? 98.920  121.565 153.429 1.00 98.38  ? 315 GLU B CG  1 
ATOM   7388  C  CD  . GLU D 1 322 ? 99.770  122.370 154.399 1.00 98.38  ? 315 GLU B CD  1 
ATOM   7389  O  OE1 . GLU D 1 322 ? 99.177  123.004 155.296 1.00 98.38  ? 315 GLU B OE1 1 
ATOM   7390  O  OE2 . GLU D 1 322 ? 100.994 122.461 154.238 1.00 98.38  ? 315 GLU B OE2 1 
ATOM   7391  N  N   . ASN D 1 323 ? 102.313 119.164 150.467 1.00 92.21  ? 316 ASN B N   1 
ATOM   7392  C  CA  . ASN D 1 323 ? 103.117 119.166 149.252 1.00 92.21  ? 316 ASN B CA  1 
ATOM   7393  C  C   . ASN D 1 323 ? 102.953 117.890 148.432 1.00 92.21  ? 316 ASN B C   1 
ATOM   7394  O  O   . ASN D 1 323 ? 103.714 117.670 147.486 1.00 92.21  ? 316 ASN B O   1 
ATOM   7395  C  CB  . ASN D 1 323 ? 104.592 119.383 149.590 1.00 92.21  ? 316 ASN B CB  1 
ATOM   7396  C  CG  . ASN D 1 323 ? 104.881 120.794 150.052 1.00 92.21  ? 316 ASN B CG  1 
ATOM   7397  O  OD1 . ASN D 1 323 ? 105.866 121.042 150.744 1.00 92.21  ? 316 ASN B OD1 1 
ATOM   7398  N  ND2 . ASN D 1 323 ? 104.015 121.728 149.674 1.00 92.21  ? 316 ASN B ND2 1 
ATOM   7399  N  N   . GLU D 1 324 ? 101.981 117.041 148.776 1.00 93.64  ? 317 GLU B N   1 
ATOM   7400  C  CA  . GLU D 1 324 ? 101.792 115.809 148.017 1.00 93.64  ? 317 GLU B CA  1 
ATOM   7401  C  C   . GLU D 1 324 ? 101.393 116.097 146.575 1.00 93.64  ? 317 GLU B C   1 
ATOM   7402  O  O   . GLU D 1 324 ? 101.911 115.468 145.647 1.00 93.64  ? 317 GLU B O   1 
ATOM   7403  C  CB  . GLU D 1 324 ? 100.752 114.907 148.690 1.00 93.64  ? 317 GLU B CB  1 
ATOM   7404  C  CG  . GLU D 1 324 ? 101.148 114.321 150.046 1.00 93.64  ? 317 GLU B CG  1 
ATOM   7405  C  CD  . GLU D 1 324 ? 100.051 113.498 150.694 1.00 93.64  ? 317 GLU B CD  1 
ATOM   7406  O  OE1 . GLU D 1 324 ? 98.910  113.527 150.190 1.00 93.64  ? 317 GLU B OE1 1 
ATOM   7407  O  OE2 . GLU D 1 324 ? 100.335 112.815 151.698 1.00 93.64  ? 317 GLU B OE2 1 
ATOM   7408  N  N   . ASP D 1 325 ? 100.480 117.047 146.363 1.00 88.81  ? 318 ASP B N   1 
ATOM   7409  C  CA  . ASP D 1 325 ? 100.043 117.356 145.004 1.00 88.81  ? 318 ASP B CA  1 
ATOM   7410  C  C   . ASP D 1 325 ? 101.153 118.024 144.202 1.00 88.81  ? 318 ASP B C   1 
ATOM   7411  O  O   . ASP D 1 325 ? 101.389 117.668 143.040 1.00 88.81  ? 318 ASP B O   1 
ATOM   7412  C  CB  . ASP D 1 325 ? 98.799  118.242 145.043 1.00 88.81  ? 318 ASP B CB  1 
ATOM   7413  C  CG  . ASP D 1 325 ? 98.860  119.278 146.145 1.00 88.81  ? 318 ASP B CG  1 
ATOM   7414  O  OD1 . ASP D 1 325 ? 97.962  119.277 147.013 1.00 88.81  ? 318 ASP B OD1 1 
ATOM   7415  O  OD2 . ASP D 1 325 ? 99.806  120.093 146.142 1.00 88.81  ? 318 ASP B OD2 1 
ATOM   7416  N  N   . PHE D 1 326 ? 101.842 118.996 144.801 1.00 83.41  ? 319 PHE B N   1 
ATOM   7417  C  CA  . PHE D 1 326 ? 102.929 119.680 144.108 1.00 83.41  ? 319 PHE B CA  1 
ATOM   7418  C  C   . PHE D 1 326 ? 104.048 118.708 143.757 1.00 83.41  ? 319 PHE B C   1 
ATOM   7419  O  O   . PHE D 1 326 ? 104.545 118.692 142.622 1.00 83.41  ? 319 PHE B O   1 
ATOM   7420  C  CB  . PHE D 1 326 ? 103.449 120.824 144.980 1.00 83.41  ? 319 PHE B CB  1 
ATOM   7421  C  CG  . PHE D 1 326 ? 104.538 121.640 144.343 1.00 83.41  ? 319 PHE B CG  1 
ATOM   7422  C  CD1 . PHE D 1 326 ? 105.868 121.286 144.491 1.00 83.41  ? 319 PHE B CD1 1 
ATOM   7423  C  CD2 . PHE D 1 326 ? 104.231 122.770 143.607 1.00 83.41  ? 319 PHE B CD2 1 
ATOM   7424  C  CE1 . PHE D 1 326 ? 106.868 122.038 143.911 1.00 83.41  ? 319 PHE B CE1 1 
ATOM   7425  C  CE2 . PHE D 1 326 ? 105.228 123.525 143.025 1.00 83.41  ? 319 PHE B CE2 1 
ATOM   7426  C  CZ  . PHE D 1 326 ? 106.547 123.158 143.178 1.00 83.41  ? 319 PHE B CZ  1 
ATOM   7427  N  N   . LEU D 1 327 ? 104.447 117.876 144.720 1.00 83.00  ? 320 LEU B N   1 
ATOM   7428  C  CA  . LEU D 1 327 ? 105.505 116.909 144.460 1.00 83.00  ? 320 LEU B CA  1 
ATOM   7429  C  C   . LEU D 1 327 ? 105.069 115.880 143.426 1.00 83.00  ? 320 LEU B C   1 
ATOM   7430  O  O   . LEU D 1 327 ? 105.866 115.470 142.581 1.00 83.00  ? 320 LEU B O   1 
ATOM   7431  C  CB  . LEU D 1 327 ? 105.929 116.224 145.757 1.00 83.00  ? 320 LEU B CB  1 
ATOM   7432  C  CG  . LEU D 1 327 ? 106.989 115.129 145.608 1.00 83.00  ? 320 LEU B CG  1 
ATOM   7433  C  CD1 . LEU D 1 327 ? 108.289 115.711 145.075 1.00 83.00  ? 320 LEU B CD1 1 
ATOM   7434  C  CD2 . LEU D 1 327 ? 107.221 114.402 146.925 1.00 83.00  ? 320 LEU B CD2 1 
ATOM   7435  N  N   . LYS D 1 328 ? 103.806 115.447 143.479 1.00 81.19  ? 321 LYS B N   1 
ATOM   7436  C  CA  . LYS D 1 328 ? 103.313 114.488 142.493 1.00 81.19  ? 321 LYS B CA  1 
ATOM   7437  C  C   . LYS D 1 328 ? 103.336 115.080 141.089 1.00 81.19  ? 321 LYS B C   1 
ATOM   7438  O  O   . LYS D 1 328 ? 103.708 114.401 140.123 1.00 81.19  ? 321 LYS B O   1 
ATOM   7439  C  CB  . LYS D 1 328 ? 101.901 114.035 142.864 1.00 81.19  ? 321 LYS B CB  1 
ATOM   7440  C  CG  . LYS D 1 328 ? 101.216 113.195 141.797 1.00 81.19  ? 321 LYS B CG  1 
ATOM   7441  C  CD  . LYS D 1 328 ? 100.053 112.403 142.373 1.00 81.19  ? 321 LYS B CD  1 
ATOM   7442  C  CE  . LYS D 1 328 ? 100.489 111.529 143.540 1.00 81.19  ? 321 LYS B CE  1 
ATOM   7443  N  NZ  . LYS D 1 328 ? 101.767 110.814 143.268 1.00 81.19  ? 321 LYS B NZ  1 
ATOM   7444  N  N   . SER D 1 329 ? 102.937 116.347 140.957 1.00 78.20  ? 322 SER B N   1 
ATOM   7445  C  CA  . SER D 1 329 ? 102.980 117.002 139.654 1.00 78.20  ? 322 SER B CA  1 
ATOM   7446  C  C   . SER D 1 329 ? 104.413 117.132 139.150 1.00 78.20  ? 322 SER B C   1 
ATOM   7447  O  O   . SER D 1 329 ? 104.689 116.891 137.968 1.00 78.20  ? 322 SER B O   1 
ATOM   7448  C  CB  . SER D 1 329 ? 102.309 118.371 139.735 1.00 78.20  ? 322 SER B CB  1 
ATOM   7449  O  OG  . SER D 1 329 ? 100.967 118.256 140.169 1.00 78.20  ? 322 SER B OG  1 
ATOM   7450  N  N   . VAL D 1 330 ? 105.342 117.505 140.034 1.00 75.36  ? 323 VAL B N   1 
ATOM   7451  C  CA  . VAL D 1 330 ? 106.740 117.593 139.622 1.00 75.36  ? 323 VAL B CA  1 
ATOM   7452  C  C   . VAL D 1 330 ? 107.258 116.223 139.203 1.00 75.36  ? 323 VAL B C   1 
ATOM   7453  O  O   . VAL D 1 330 ? 107.996 116.099 138.217 1.00 75.36  ? 323 VAL B O   1 
ATOM   7454  C  CB  . VAL D 1 330 ? 107.599 118.211 140.742 1.00 75.36  ? 323 VAL B CB  1 
ATOM   7455  C  CG1 . VAL D 1 330 ? 109.067 118.181 140.358 1.00 75.36  ? 323 VAL B CG1 1 
ATOM   7456  C  CG2 . VAL D 1 330 ? 107.160 119.636 141.015 1.00 75.36  ? 323 VAL B CG2 1 
ATOM   7457  N  N   . THR D 1 331 ? 106.877 115.171 139.935 1.00 77.30  ? 324 THR B N   1 
ATOM   7458  C  CA  . THR D 1 331 ? 107.338 113.826 139.604 1.00 77.30  ? 324 THR B CA  1 
ATOM   7459  C  C   . THR D 1 331 ? 106.814 113.373 138.250 1.00 77.30  ? 324 THR B C   1 
ATOM   7460  O  O   . THR D 1 331 ? 107.564 112.799 137.453 1.00 77.30  ? 324 THR B O   1 
ATOM   7461  C  CB  . THR D 1 331 ? 106.918 112.826 140.682 1.00 77.30  ? 324 THR B CB  1 
ATOM   7462  O  OG1 . THR D 1 331 ? 105.509 112.927 140.911 1.00 77.30  ? 324 THR B OG1 1 
ATOM   7463  C  CG2 . THR D 1 331 ? 107.669 113.068 141.983 1.00 77.30  ? 324 THR B CG2 1 
ATOM   7464  N  N   . THR D 1 332 ? 105.528 113.603 137.971 1.00 78.09  ? 325 THR B N   1 
ATOM   7465  C  CA  . THR D 1 332 ? 105.003 113.172 136.678 1.00 78.09  ? 325 THR B CA  1 
ATOM   7466  C  C   . THR D 1 332 ? 105.582 114.006 135.540 1.00 78.09  ? 325 THR B C   1 
ATOM   7467  O  O   . THR D 1 332 ? 105.837 113.470 134.454 1.00 78.09  ? 325 THR B O   1 
ATOM   7468  C  CB  . THR D 1 332 ? 103.471 113.207 136.665 1.00 78.09  ? 325 THR B CB  1 
ATOM   7469  O  OG1 . THR D 1 332 ? 102.996 112.744 135.394 1.00 78.09  ? 325 THR B OG1 1 
ATOM   7470  C  CG2 . THR D 1 332 ? 102.940 114.602 136.910 1.00 78.09  ? 325 THR B CG2 1 
ATOM   7471  N  N   . LEU D 1 333 ? 105.832 115.299 135.772 1.00 71.03  ? 326 LEU B N   1 
ATOM   7472  C  CA  . LEU D 1 333 ? 106.499 116.105 134.755 1.00 71.03  ? 326 LEU B CA  1 
ATOM   7473  C  C   . LEU D 1 333 ? 107.907 115.591 134.484 1.00 71.03  ? 326 LEU B C   1 
ATOM   7474  O  O   . LEU D 1 333 ? 108.330 115.496 133.325 1.00 71.03  ? 326 LEU B O   1 
ATOM   7475  C  CB  . LEU D 1 333 ? 106.535 117.570 135.188 1.00 71.03  ? 326 LEU B CB  1 
ATOM   7476  C  CG  . LEU D 1 333 ? 107.140 118.543 134.179 1.00 71.03  ? 326 LEU B CG  1 
ATOM   7477  C  CD1 . LEU D 1 333 ? 106.239 118.669 132.963 1.00 71.03  ? 326 LEU B CD1 1 
ATOM   7478  C  CD2 . LEU D 1 333 ? 107.372 119.898 134.819 1.00 71.03  ? 326 LEU B CD2 1 
ATOM   7479  N  N   . ALA D 1 334 ? 108.645 115.245 135.539 1.00 71.28  ? 327 ALA B N   1 
ATOM   7480  C  CA  . ALA D 1 334 ? 109.990 114.710 135.362 1.00 71.28  ? 327 ALA B CA  1 
ATOM   7481  C  C   . ALA D 1 334 ? 109.963 113.369 134.639 1.00 71.28  ? 327 ALA B C   1 
ATOM   7482  O  O   . ALA D 1 334 ? 110.814 113.103 133.783 1.00 71.28  ? 327 ALA B O   1 
ATOM   7483  C  CB  . ALA D 1 334 ? 110.683 114.575 136.717 1.00 71.28  ? 327 ALA B CB  1 
ATOM   7484  N  N   . MET D 1 335 ? 109.000 112.509 134.975 1.00 75.18  ? 328 MET B N   1 
ATOM   7485  C  CA  . MET D 1 335 ? 108.882 111.225 134.293 1.00 75.18  ? 328 MET B CA  1 
ATOM   7486  C  C   . MET D 1 335 ? 108.583 111.419 132.813 1.00 75.18  ? 328 MET B C   1 
ATOM   7487  O  O   . MET D 1 335 ? 109.145 110.721 131.961 1.00 75.18  ? 328 MET B O   1 
ATOM   7488  C  CB  . MET D 1 335 ? 107.799 110.375 134.955 1.00 75.18  ? 328 MET B CB  1 
ATOM   7489  C  CG  . MET D 1 335 ? 107.753 108.937 134.468 1.00 75.18  ? 328 MET B CG  1 
ATOM   7490  S  SD  . MET D 1 335 ? 106.070 108.297 134.356 1.00 75.18  ? 328 MET B SD  1 
ATOM   7491  C  CE  . MET D 1 335 ? 105.733 108.532 132.613 1.00 75.18  ? 328 MET B CE  1 
ATOM   7492  N  N   . LYS D 1 336 ? 107.699 112.365 132.489 1.00 72.76  ? 329 LYS B N   1 
ATOM   7493  C  CA  . LYS D 1 336 ? 107.428 112.671 131.090 1.00 72.76  ? 329 LYS B CA  1 
ATOM   7494  C  C   . LYS D 1 336 ? 108.663 113.225 130.389 1.00 72.76  ? 329 LYS B C   1 
ATOM   7495  O  O   . LYS D 1 336 ? 108.898 112.917 129.215 1.00 72.76  ? 329 LYS B O   1 
ATOM   7496  C  CB  . LYS D 1 336 ? 106.260 113.654 130.994 1.00 72.76  ? 329 LYS B CB  1 
ATOM   7497  C  CG  . LYS D 1 336 ? 106.211 114.470 129.712 1.00 72.76  ? 329 LYS B CG  1 
ATOM   7498  C  CD  . LYS D 1 336 ? 105.066 115.475 129.735 1.00 72.76  ? 329 LYS B CD  1 
ATOM   7499  C  CE  . LYS D 1 336 ? 103.804 114.879 130.340 1.00 72.76  ? 329 LYS B CE  1 
ATOM   7500  N  NZ  . LYS D 1 336 ? 102.595 115.675 129.995 1.00 72.76  ? 329 LYS B NZ  1 
ATOM   7501  N  N   . ALA D 1 337 ? 109.467 114.021 131.091 1.00 71.49  ? 330 ALA B N   1 
ATOM   7502  C  CA  . ALA D 1 337 ? 110.650 114.641 130.510 1.00 71.49  ? 330 ALA B CA  1 
ATOM   7503  C  C   . ALA D 1 337 ? 111.878 113.738 130.527 1.00 71.49  ? 330 ALA B C   1 
ATOM   7504  O  O   . ALA D 1 337 ? 112.923 114.137 130.003 1.00 71.49  ? 330 ALA B O   1 
ATOM   7505  C  CB  . ALA D 1 337 ? 110.970 115.948 131.241 1.00 71.49  ? 330 ALA B CB  1 
ATOM   7506  N  N   . LYS D 1 338 ? 111.781 112.546 131.117 1.00 71.50  ? 331 LYS B N   1 
ATOM   7507  C  CA  . LYS D 1 338 ? 112.859 111.555 131.125 1.00 71.50  ? 331 LYS B CA  1 
ATOM   7508  C  C   . LYS D 1 338 ? 114.118 112.113 131.801 1.00 71.50  ? 331 LYS B C   1 
ATOM   7509  O  O   . LYS D 1 338 ? 115.160 112.336 131.179 1.00 71.50  ? 331 LYS B O   1 
ATOM   7510  C  CB  . LYS D 1 338 ? 113.159 111.072 129.699 1.00 71.50  ? 331 LYS B CB  1 
ATOM   7511  C  CG  . LYS D 1 338 ? 114.098 109.879 129.618 1.00 71.50  ? 331 LYS B CG  1 
ATOM   7512  C  CD  . LYS D 1 338 ? 113.535 108.683 130.363 1.00 71.50  ? 331 LYS B CD  1 
ATOM   7513  C  CE  . LYS D 1 338 ? 112.272 108.167 129.694 1.00 71.50  ? 331 LYS B CE  1 
ATOM   7514  N  NZ  . LYS D 1 338 ? 112.568 107.486 128.404 1.00 71.50  ? 331 LYS B NZ  1 
ATOM   7515  N  N   . CYS D 1 339 ? 113.983 112.354 133.105 1.00 63.58  ? 332 CYS B N   1 
ATOM   7516  C  CA  . CYS D 1 339 ? 115.086 112.836 133.924 1.00 63.58  ? 332 CYS B CA  1 
ATOM   7517  C  C   . CYS D 1 339 ? 115.009 112.185 135.301 1.00 63.58  ? 332 CYS B C   1 
ATOM   7518  O  O   . CYS D 1 339 ? 114.111 111.387 135.586 1.00 63.58  ? 332 CYS B O   1 
ATOM   7519  C  CB  . CYS D 1 339 ? 115.071 114.365 134.030 1.00 63.58  ? 332 CYS B CB  1 
ATOM   7520  S  SG  . CYS D 1 339 ? 113.489 115.057 134.546 1.00 63.58  ? 332 CYS B SG  1 
ATOM   7521  N  N   . LYS D 1 340 ? 115.964 112.533 136.158 1.00 59.53  ? 333 LYS B N   1 
ATOM   7522  C  CA  . LYS D 1 340 ? 116.047 112.014 137.513 1.00 59.53  ? 333 LYS B CA  1 
ATOM   7523  C  C   . LYS D 1 340 ? 115.218 112.889 138.449 1.00 59.53  ? 333 LYS B C   1 
ATOM   7524  O  O   . LYS D 1 340 ? 114.464 113.763 138.011 1.00 59.53  ? 333 LYS B O   1 
ATOM   7525  C  CB  . LYS D 1 340 ? 117.507 111.944 137.963 1.00 59.53  ? 333 LYS B CB  1 
ATOM   7526  C  CG  . LYS D 1 340 ? 118.333 110.896 137.247 1.00 59.53  ? 333 LYS B CG  1 
ATOM   7527  C  CD  . LYS D 1 340 ? 119.747 110.848 137.801 1.00 59.53  ? 333 LYS B CD  1 
ATOM   7528  C  CE  . LYS D 1 340 ? 120.574 109.782 137.108 1.00 59.53  ? 333 LYS B CE  1 
ATOM   7529  N  NZ  . LYS D 1 340 ? 121.949 109.693 137.671 1.00 59.53  ? 333 LYS B NZ  1 
ATOM   7530  N  N   . LEU D 1 341 ? 115.360 112.661 139.753 1.00 55.49  ? 334 LEU B N   1 
ATOM   7531  C  CA  . LEU D 1 341 ? 114.661 113.445 140.761 1.00 55.49  ? 334 LEU B CA  1 
ATOM   7532  C  C   . LEU D 1 341 ? 115.355 113.289 142.103 1.00 55.49  ? 334 LEU B C   1 
ATOM   7533  O  O   . LEU D 1 341 ? 115.751 112.184 142.481 1.00 55.49  ? 334 LEU B O   1 
ATOM   7534  C  CB  . LEU D 1 341 ? 113.196 113.023 140.884 1.00 55.49  ? 334 LEU B CB  1 
ATOM   7535  C  CG  . LEU D 1 341 ? 112.198 113.910 140.148 1.00 55.49  ? 334 LEU B CG  1 
ATOM   7536  C  CD1 . LEU D 1 341 ? 110.800 113.423 140.403 1.00 55.49  ? 334 LEU B CD1 1 
ATOM   7537  C  CD2 . LEU D 1 341 ? 112.355 115.349 140.598 1.00 55.49  ? 334 LEU B CD2 1 
ATOM   7538  N  N   . THR D 1 342 ? 115.496 114.402 142.818 1.00 58.30  ? 335 THR B N   1 
ATOM   7539  C  CA  . THR D 1 342 ? 116.064 114.406 144.158 1.00 58.30  ? 335 THR B CA  1 
ATOM   7540  C  C   . THR D 1 342 ? 115.173 115.249 145.055 1.00 58.30  ? 335 THR B C   1 
ATOM   7541  O  O   . THR D 1 342 ? 114.829 116.381 144.701 1.00 58.30  ? 335 THR B O   1 
ATOM   7542  C  CB  . THR D 1 342 ? 117.495 114.953 144.157 1.00 58.30  ? 335 THR B CB  1 
ATOM   7543  O  OG1 . THR D 1 342 ? 118.355 114.038 143.468 1.00 58.30  ? 335 THR B OG1 1 
ATOM   7544  C  CG2 . THR D 1 342 ? 117.997 115.134 145.577 1.00 58.30  ? 335 THR B CG2 1 
ATOM   7545  N  N   . ILE D 1 343 ? 114.801 114.702 146.210 1.00 70.18  ? 336 ILE B N   1 
ATOM   7546  C  CA  . ILE D 1 343 ? 113.864 115.345 147.120 1.00 70.18  ? 336 ILE B CA  1 
ATOM   7547  C  C   . ILE D 1 343 ? 114.491 115.434 148.504 1.00 70.18  ? 336 ILE B C   1 
ATOM   7548  O  O   . ILE D 1 343 ? 115.078 114.463 148.994 1.00 70.18  ? 336 ILE B O   1 
ATOM   7549  C  CB  . ILE D 1 343 ? 112.524 114.586 147.179 1.00 70.18  ? 336 ILE B CB  1 
ATOM   7550  C  CG1 . ILE D 1 343 ? 112.772 113.078 147.233 1.00 70.18  ? 336 ILE B CG1 1 
ATOM   7551  C  CG2 . ILE D 1 343 ? 111.655 114.949 145.988 1.00 70.18  ? 336 ILE B CG2 1 
ATOM   7552  C  CD1 . ILE D 1 343 ? 111.509 112.250 147.224 1.00 70.18  ? 336 ILE B CD1 1 
ATOM   7553  N  N   . CYS D 1 344 ? 114.367 116.604 149.130 1.00 81.75  ? 337 CYS B N   1 
ATOM   7554  C  CA  . CYS D 1 344 ? 114.871 116.814 150.478 1.00 81.75  ? 337 CYS B CA  1 
ATOM   7555  C  C   . CYS D 1 344 ? 113.750 116.617 151.484 1.00 81.75  ? 337 CYS B C   1 
ATOM   7556  O  O   . CYS D 1 344 ? 112.745 117.340 151.424 1.00 81.75  ? 337 CYS B O   1 
ATOM   7557  C  CB  . CYS D 1 344 ? 115.469 118.211 150.621 1.00 81.75  ? 337 CYS B CB  1 
ATOM   7558  S  SG  . CYS D 1 344 ? 116.903 118.282 151.713 1.00 81.75  ? 337 CYS B SG  1 
ATOM   7559  N  N   . PRO D 1 345 ? 113.868 115.674 152.414 1.00 87.37  ? 338 PRO B N   1 
ATOM   7560  C  CA  . PRO D 1 345 ? 112.840 115.519 153.447 1.00 87.37  ? 338 PRO B CA  1 
ATOM   7561  C  C   . PRO D 1 345 ? 112.901 116.657 154.457 1.00 87.37  ? 338 PRO B C   1 
ATOM   7562  O  O   . PRO D 1 345 ? 113.883 117.395 154.555 1.00 87.37  ? 338 PRO B O   1 
ATOM   7563  C  CB  . PRO D 1 345 ? 113.184 114.172 154.084 1.00 87.37  ? 338 PRO B CB  1 
ATOM   7564  C  CG  . PRO D 1 345 ? 114.656 114.045 153.891 1.00 87.37  ? 338 PRO B CG  1 
ATOM   7565  C  CD  . PRO D 1 345 ? 114.963 114.702 152.571 1.00 87.37  ? 338 PRO B CD  1 
ATOM   7566  N  N   . GLU D 1 346 ? 111.815 116.788 155.222 1.00 91.28  ? 339 GLU B N   1 
ATOM   7567  C  CA  . GLU D 1 346 ? 111.656 117.936 156.108 1.00 91.28  ? 339 GLU B CA  1 
ATOM   7568  C  C   . GLU D 1 346 ? 112.658 117.952 157.255 1.00 91.28  ? 339 GLU B C   1 
ATOM   7569  O  O   . GLU D 1 346 ? 112.866 119.010 157.858 1.00 91.28  ? 339 GLU B O   1 
ATOM   7570  C  CB  . GLU D 1 346 ? 110.229 117.977 156.661 1.00 91.28  ? 339 GLU B CB  1 
ATOM   7571  C  CG  . GLU D 1 346 ? 110.052 117.294 158.006 1.00 91.28  ? 339 GLU B CG  1 
ATOM   7572  C  CD  . GLU D 1 346 ? 109.934 115.787 157.889 1.00 91.28  ? 339 GLU B CD  1 
ATOM   7573  O  OE1 . GLU D 1 346 ? 110.057 115.260 156.762 1.00 91.28  ? 339 GLU B OE1 1 
ATOM   7574  O  OE2 . GLU D 1 346 ? 109.719 115.125 158.926 1.00 91.28  ? 339 GLU B OE2 1 
ATOM   7575  N  N   . GLU D 1 347 ? 113.276 116.813 157.580 1.00 91.70  ? 340 GLU B N   1 
ATOM   7576  C  CA  . GLU D 1 347 ? 114.251 116.795 158.668 1.00 91.70  ? 340 GLU B CA  1 
ATOM   7577  C  C   . GLU D 1 347 ? 115.465 117.655 158.340 1.00 91.70  ? 340 GLU B C   1 
ATOM   7578  O  O   . GLU D 1 347 ? 115.936 118.425 159.186 1.00 91.70  ? 340 GLU B O   1 
ATOM   7579  C  CB  . GLU D 1 347 ? 114.676 115.358 158.982 1.00 91.70  ? 340 GLU B CB  1 
ATOM   7580  C  CG  . GLU D 1 347 ? 113.548 114.429 159.430 1.00 91.70  ? 340 GLU B CG  1 
ATOM   7581  C  CD  . GLU D 1 347 ? 112.682 113.928 158.289 1.00 91.70  ? 340 GLU B CD  1 
ATOM   7582  O  OE1 . GLU D 1 347 ? 112.815 114.447 157.161 1.00 91.70  ? 340 GLU B OE1 1 
ATOM   7583  O  OE2 . GLU D 1 347 ? 111.867 113.010 158.519 1.00 91.70  ? 340 GLU B OE2 1 
ATOM   7584  N  N   . GLU D 1 348 ? 115.988 117.540 157.121 1.00 86.66  ? 341 GLU B N   1 
ATOM   7585  C  CA  . GLU D 1 348 ? 117.098 118.373 156.679 1.00 86.66  ? 341 GLU B CA  1 
ATOM   7586  C  C   . GLU D 1 348 ? 116.632 119.661 156.011 1.00 86.66  ? 341 GLU B C   1 
ATOM   7587  O  O   . GLU D 1 348 ? 117.455 120.544 155.747 1.00 86.66  ? 341 GLU B O   1 
ATOM   7588  C  CB  . GLU D 1 348 ? 117.992 117.579 155.718 1.00 86.66  ? 341 GLU B CB  1 
ATOM   7589  C  CG  . GLU D 1 348 ? 119.364 118.188 155.469 1.00 86.66  ? 341 GLU B CG  1 
ATOM   7590  C  CD  . GLU D 1 348 ? 120.439 117.571 156.341 1.00 86.66  ? 341 GLU B CD  1 
ATOM   7591  O  OE1 . GLU D 1 348 ? 120.112 116.665 157.135 1.00 86.66  ? 341 GLU B OE1 1 
ATOM   7592  O  OE2 . GLU D 1 348 ? 121.609 117.992 156.232 1.00 86.66  ? 341 GLU B OE2 1 
ATOM   7593  N  N   . ASN D 1 349 ? 115.327 119.778 155.758 1.00 83.34  ? 342 ASN B N   1 
ATOM   7594  C  CA  . ASN D 1 349 ? 114.786 120.960 155.032 1.00 83.34  ? 342 ASN B CA  1 
ATOM   7595  C  C   . ASN D 1 349 ? 114.740 122.186 155.950 1.00 83.34  ? 342 ASN B C   1 
ATOM   7596  O  O   . ASN D 1 349 ? 114.992 123.299 155.446 1.00 83.34  ? 342 ASN B O   1 
ATOM   7597  C  CB  . ASN D 1 349 ? 113.393 120.650 154.486 1.00 83.34  ? 342 ASN B CB  1 
ATOM   7598  C  CG  . ASN D 1 349 ? 112.887 121.710 153.538 1.00 83.34  ? 342 ASN B CG  1 
ATOM   7599  O  OD1 . ASN D 1 349 ? 111.936 122.420 153.852 1.00 83.34  ? 342 ASN B OD1 1 
ATOM   7600  N  ND2 . ASN D 1 349 ? 113.535 121.843 152.391 1.00 83.34  ? 342 ASN B ND2 1 
ATOM   7601  N  N   . MET D 1 350 ? 114.419 121.993 157.231 1.00 83.31  ? 343 MET B N   1 
ATOM   7602  C  CA  . MET D 1 350 ? 114.304 123.084 158.203 1.00 83.31  ? 343 MET B CA  1 
ATOM   7603  C  C   . MET D 1 350 ? 113.323 124.157 157.733 1.00 83.31  ? 343 MET B C   1 
ATOM   7604  O  O   . MET D 1 350 ? 113.572 125.355 157.875 1.00 83.31  ? 343 MET B O   1 
ATOM   7605  C  CB  . MET D 1 350 ? 115.671 123.697 158.517 1.00 83.31  ? 343 MET B CB  1 
ATOM   7606  C  CG  . MET D 1 350 ? 116.732 122.683 158.905 1.00 83.31  ? 343 MET B CG  1 
ATOM   7607  S  SD  . MET D 1 350 ? 116.849 122.464 160.691 1.00 83.31  ? 343 MET B SD  1 
ATOM   7608  C  CE  . MET D 1 350 ? 117.312 124.115 161.206 1.00 83.31  ? 343 MET B CE  1 
ATOM   7609  N  N   . ASP D 1 351 ? 112.199 123.717 157.162 1.00 80.32  ? 344 ASP B N   1 
ATOM   7610  C  CA  . ASP D 1 351 ? 111.107 124.604 156.758 1.00 80.32  ? 344 ASP B CA  1 
ATOM   7611  C  C   . ASP D 1 351 ? 111.568 125.652 155.746 1.00 80.32  ? 344 ASP B C   1 
ATOM   7612  O  O   . ASP D 1 351 ? 111.125 126.801 155.768 1.00 80.32  ? 344 ASP B O   1 
ATOM   7613  C  CB  . ASP D 1 351 ? 110.465 125.276 157.974 1.00 80.32  ? 344 ASP B CB  1 
ATOM   7614  C  CG  . ASP D 1 351 ? 109.933 124.274 158.979 1.00 80.32  ? 344 ASP B CG  1 
ATOM   7615  O  OD1 . ASP D 1 351 ? 110.061 123.058 158.730 1.00 80.32  ? 344 ASP B OD1 1 
ATOM   7616  O  OD2 . ASP D 1 351 ? 109.386 124.704 160.016 1.00 80.32  ? 344 ASP B OD2 1 
ATOM   7617  N  N   . ASP D 1 352 ? 112.466 125.254 154.850 1.00 72.25  ? 345 ASP B N   1 
ATOM   7618  C  CA  . ASP D 1 352 ? 112.923 126.100 153.755 1.00 72.25  ? 345 ASP B CA  1 
ATOM   7619  C  C   . ASP D 1 352 ? 112.635 125.390 152.442 1.00 72.25  ? 345 ASP B C   1 
ATOM   7620  O  O   . ASP D 1 352 ? 113.126 124.280 152.216 1.00 72.25  ? 345 ASP B O   1 
ATOM   7621  C  CB  . ASP D 1 352 ? 114.417 126.407 153.881 1.00 72.25  ? 345 ASP B CB  1 
ATOM   7622  C  CG  . ASP D 1 352 ? 114.907 127.363 152.816 1.00 72.25  ? 345 ASP B CG  1 
ATOM   7623  O  OD1 . ASP D 1 352 ? 114.084 127.805 151.987 1.00 72.25  ? 345 ASP B OD1 1 
ATOM   7624  O  OD2 . ASP D 1 352 ? 116.116 127.674 152.803 1.00 72.25  ? 345 ASP B OD2 1 
ATOM   7625  N  N   . GLN D 1 353 ? 111.844 126.025 151.577 1.00 69.97  ? 346 GLN B N   1 
ATOM   7626  C  CA  . GLN D 1 353 ? 111.393 125.382 150.350 1.00 69.97  ? 346 GLN B CA  1 
ATOM   7627  C  C   . GLN D 1 353 ? 111.898 126.072 149.089 1.00 69.97  ? 346 GLN B C   1 
ATOM   7628  O  O   . GLN D 1 353 ? 111.514 125.667 147.986 1.00 69.97  ? 346 GLN B O   1 
ATOM   7629  C  CB  . GLN D 1 353 ? 109.860 125.303 150.303 1.00 69.97  ? 346 GLN B CB  1 
ATOM   7630  C  CG  . GLN D 1 353 ? 109.109 126.627 150.114 1.00 69.97  ? 346 GLN B CG  1 
ATOM   7631  C  CD  . GLN D 1 353 ? 109.060 127.516 151.352 1.00 69.97  ? 346 GLN B CD  1 
ATOM   7632  O  OE1 . GLN D 1 353 ? 109.588 127.178 152.410 1.00 69.97  ? 346 GLN B OE1 1 
ATOM   7633  N  NE2 . GLN D 1 353 ? 108.414 128.667 151.216 1.00 69.97  ? 346 GLN B NE2 1 
ATOM   7634  N  N   . TRP D 1 354 ? 112.745 127.088 149.216 1.00 64.86  ? 347 TRP B N   1 
ATOM   7635  C  CA  . TRP D 1 354 ? 113.226 127.850 148.065 1.00 64.86  ? 347 TRP B CA  1 
ATOM   7636  C  C   . TRP D 1 354 ? 114.610 127.331 147.697 1.00 64.86  ? 347 TRP B C   1 
ATOM   7637  O  O   . TRP D 1 354 ? 115.632 127.914 148.060 1.00 64.86  ? 347 TRP B O   1 
ATOM   7638  C  CB  . TRP D 1 354 ? 113.231 129.340 148.379 1.00 64.86  ? 347 TRP B CB  1 
ATOM   7639  C  CG  . TRP D 1 354 ? 111.852 129.897 148.494 1.00 64.86  ? 347 TRP B CG  1 
ATOM   7640  C  CD1 . TRP D 1 354 ? 110.843 129.777 147.586 1.00 64.86  ? 347 TRP B CD1 1 
ATOM   7641  C  CD2 . TRP D 1 354 ? 111.314 130.630 149.597 1.00 64.86  ? 347 TRP B CD2 1 
ATOM   7642  N  NE1 . TRP D 1 354 ? 109.715 130.405 148.046 1.00 64.86  ? 347 TRP B NE1 1 
ATOM   7643  C  CE2 . TRP D 1 354 ? 109.978 130.937 149.281 1.00 64.86  ? 347 TRP B CE2 1 
ATOM   7644  C  CE3 . TRP D 1 354 ? 111.835 131.064 150.819 1.00 64.86  ? 347 TRP B CE3 1 
ATOM   7645  C  CZ2 . TRP D 1 354 ? 109.157 131.654 150.140 1.00 64.86  ? 347 TRP B CZ2 1 
ATOM   7646  C  CZ3 . TRP D 1 354 ? 111.018 131.779 151.671 1.00 64.86  ? 347 TRP B CZ3 1 
ATOM   7647  C  CH2 . TRP D 1 354 ? 109.694 132.067 151.328 1.00 64.86  ? 347 TRP B CH2 1 
ATOM   7648  N  N   . MET D 1 355 ? 114.636 126.217 146.964 1.00 59.78  ? 348 MET B N   1 
ATOM   7649  C  CA  . MET D 1 355 ? 115.899 125.653 146.506 1.00 59.78  ? 348 MET B CA  1 
ATOM   7650  C  C   . MET D 1 355 ? 116.570 126.536 145.465 1.00 59.78  ? 348 MET B C   1 
ATOM   7651  O  O   . MET D 1 355 ? 117.803 126.581 145.400 1.00 59.78  ? 348 MET B O   1 
ATOM   7652  C  CB  . MET D 1 355 ? 115.677 124.259 145.923 1.00 59.78  ? 348 MET B CB  1 
ATOM   7653  C  CG  . MET D 1 355 ? 116.791 123.274 146.221 1.00 59.78  ? 348 MET B CG  1 
ATOM   7654  S  SD  . MET D 1 355 ? 116.170 121.614 146.539 1.00 59.78  ? 348 MET B SD  1 
ATOM   7655  C  CE  . MET D 1 355 ? 115.878 121.685 148.301 1.00 59.78  ? 348 MET B CE  1 
ATOM   7656  N  N   . GLN D 1 356 ? 115.780 127.233 144.646 1.00 54.06  ? 349 GLN B N   1 
ATOM   7657  C  CA  . GLN D 1 356 ? 116.341 128.042 143.568 1.00 54.06  ? 349 GLN B CA  1 
ATOM   7658  C  C   . GLN D 1 356 ? 117.202 129.176 144.110 1.00 54.06  ? 349 GLN B C   1 
ATOM   7659  O  O   . GLN D 1 356 ? 118.272 129.464 143.562 1.00 54.06  ? 349 GLN B O   1 
ATOM   7660  C  CB  . GLN D 1 356 ? 115.214 128.594 142.697 1.00 54.06  ? 349 GLN B CB  1 
ATOM   7661  C  CG  . GLN D 1 356 ? 115.642 129.602 141.637 1.00 54.06  ? 349 GLN B CG  1 
ATOM   7662  C  CD  . GLN D 1 356 ? 116.655 129.048 140.655 1.00 54.06  ? 349 GLN B CD  1 
ATOM   7663  O  OE1 . GLN D 1 356 ? 116.293 128.562 139.584 1.00 54.06  ? 349 GLN B OE1 1 
ATOM   7664  N  NE2 . GLN D 1 356 ? 117.934 129.143 141.000 1.00 54.06  ? 349 GLN B NE2 1 
ATOM   7665  N  N   . ASP D 1 357 ? 116.758 129.827 145.183 1.00 52.48  ? 350 ASP B N   1 
ATOM   7666  C  CA  . ASP D 1 357 ? 117.438 131.006 145.701 1.00 52.48  ? 350 ASP B CA  1 
ATOM   7667  C  C   . ASP D 1 357 ? 118.751 130.692 146.405 1.00 52.48  ? 350 ASP B C   1 
ATOM   7668  O  O   . ASP D 1 357 ? 119.524 131.618 146.669 1.00 52.48  ? 350 ASP B O   1 
ATOM   7669  C  CB  . ASP D 1 357 ? 116.519 131.756 146.669 1.00 52.48  ? 350 ASP B CB  1 
ATOM   7670  C  CG  . ASP D 1 357 ? 115.169 132.074 146.063 1.00 52.48  ? 350 ASP B CG  1 
ATOM   7671  O  OD1 . ASP D 1 357 ? 114.955 131.740 144.880 1.00 52.48  ? 350 ASP B OD1 1 
ATOM   7672  O  OD2 . ASP D 1 357 ? 114.321 132.659 146.770 1.00 52.48  ? 350 ASP B OD2 1 
ATOM   7673  N  N   . GLU D 1 358 ? 119.026 129.428 146.717 1.00 50.73  ? 351 GLU B N   1 
ATOM   7674  C  CA  . GLU D 1 358 ? 120.193 129.075 147.515 1.00 50.73  ? 351 GLU B CA  1 
ATOM   7675  C  C   . GLU D 1 358 ? 121.356 128.546 146.687 1.00 50.73  ? 351 GLU B C   1 
ATOM   7676  O  O   . GLU D 1 358 ? 122.512 128.860 146.984 1.00 50.73  ? 351 GLU B O   1 
ATOM   7677  C  CB  . GLU D 1 358 ? 119.812 128.032 148.572 1.00 50.73  ? 351 GLU B CB  1 
ATOM   7678  C  CG  . GLU D 1 358 ? 120.990 127.496 149.365 1.00 50.73  ? 351 GLU B CG  1 
ATOM   7679  C  CD  . GLU D 1 358 ? 121.283 128.323 150.599 1.00 50.73  ? 351 GLU B CD  1 
ATOM   7680  O  OE1 . GLU D 1 358 ? 120.446 129.179 150.954 1.00 50.73  ? 351 GLU B OE1 1 
ATOM   7681  O  OE2 . GLU D 1 358 ? 122.356 128.125 151.208 1.00 50.73  ? 351 GLU B OE2 1 
ATOM   7682  N  N   . MET D 1 359 ? 121.037 127.724 145.685 1.00 44.45  ? 352 MET B N   1 
ATOM   7683  C  CA  . MET D 1 359 ? 122.124 127.066 144.919 1.00 44.45  ? 352 MET B CA  1 
ATOM   7684  C  C   . MET D 1 359 ? 121.904 127.207 143.413 1.00 44.45  ? 352 MET B C   1 
ATOM   7685  O  O   . MET D 1 359 ? 120.734 127.246 142.983 1.00 44.45  ? 352 MET B O   1 
ATOM   7686  C  CB  . MET D 1 359 ? 122.182 125.576 145.269 1.00 44.45  ? 352 MET B CB  1 
ATOM   7687  C  CG  . MET D 1 359 ? 120.827 124.897 145.201 1.00 44.45  ? 352 MET B CG  1 
ATOM   7688  S  SD  . MET D 1 359 ? 120.673 123.486 146.323 1.00 44.45  ? 352 MET B SD  1 
ATOM   7689  C  CE  . MET D 1 359 ? 119.808 124.256 147.691 1.00 44.45  ? 352 MET B CE  1 
ATOM   7690  N  N   . GLU D 1 360 ? 122.994 127.297 142.653 1.00 40.54  ? 353 GLU B N   1 
ATOM   7691  C  CA  . GLU D 1 360 ? 122.937 127.350 141.198 1.00 40.54  ? 353 GLU B CA  1 
ATOM   7692  C  C   . GLU D 1 360 ? 123.956 126.380 140.625 1.00 40.54  ? 353 GLU B C   1 
ATOM   7693  O  O   . GLU D 1 360 ? 125.103 126.348 141.069 1.00 40.54  ? 353 GLU B O   1 
ATOM   7694  C  CB  . GLU D 1 360 ? 123.207 128.764 140.677 1.00 40.54  ? 353 GLU B CB  1 
ATOM   7695  C  CG  . GLU D 1 360 ? 122.993 128.929 139.186 1.00 40.54  ? 353 GLU B CG  1 
ATOM   7696  C  CD  . GLU D 1 360 ? 121.568 129.313 138.829 1.00 40.54  ? 353 GLU B CD  1 
ATOM   7697  O  OE1 . GLU D 1 360 ? 120.971 130.141 139.548 1.00 40.54  ? 353 GLU B OE1 1 
ATOM   7698  O  OE2 . GLU D 1 360 ? 121.046 128.792 137.823 1.00 40.54  ? 353 GLU B OE2 1 
ATOM   7699  N  N   . ILE D 1 361 ? 123.508 125.564 139.664 1.00 32.99  ? 354 ILE B N   1 
ATOM   7700  C  CA  . ILE D 1 361 ? 124.393 124.487 139.129 1.00 32.99  ? 354 ILE B CA  1 
ATOM   7701  C  C   . ILE D 1 361 ? 124.985 124.874 137.775 1.00 32.99  ? 354 ILE B C   1 
ATOM   7702  O  O   . ILE D 1 361 ? 124.204 125.177 136.852 1.00 32.99  ? 354 ILE B O   1 
ATOM   7703  C  CB  . ILE D 1 361 ? 123.628 123.151 139.033 1.00 32.99  ? 354 ILE B CB  1 
ATOM   7704  C  CG1 . ILE D 1 361 ? 122.878 122.825 140.326 1.00 32.99  ? 354 ILE B CG1 1 
ATOM   7705  C  CG2 . ILE D 1 361 ? 124.572 122.028 138.635 1.00 32.99  ? 354 ILE B CG2 1 
ATOM   7706  C  CD1 . ILE D 1 361 ? 123.772 122.345 141.443 1.00 32.99  ? 354 ILE B CD1 1 
ATOM   7707  N  N   . GLY D 1 362 ? 126.312 124.861 137.669 1.00 26.70  ? 355 GLY B N   1 
ATOM   7708  C  CA  . GLY D 1 362 ? 127.006 125.105 136.421 1.00 26.70  ? 355 GLY B CA  1 
ATOM   7709  C  C   . GLY D 1 362 ? 127.974 123.976 136.151 1.00 26.70  ? 355 GLY B C   1 
ATOM   7710  O  O   . GLY D 1 362 ? 127.913 122.952 136.832 1.00 26.70  ? 355 GLY B O   1 
ATOM   7711  N  N   . TYR D 1 363 ? 128.880 124.134 135.192 1.00 21.08  ? 356 TYR B N   1 
ATOM   7712  C  CA  . TYR D 1 363 ? 129.844 123.083 134.903 1.00 21.08  ? 356 TYR B CA  1 
ATOM   7713  C  C   . TYR D 1 363 ? 131.211 123.698 134.655 1.00 21.08  ? 356 TYR B C   1 
ATOM   7714  O  O   . TYR D 1 363 ? 131.329 124.866 134.282 1.00 21.08  ? 356 TYR B O   1 
ATOM   7715  C  CB  . TYR D 1 363 ? 129.417 122.236 133.695 1.00 21.08  ? 356 TYR B CB  1 
ATOM   7716  C  CG  . TYR D 1 363 ? 129.479 122.950 132.363 1.00 21.08  ? 356 TYR B CG  1 
ATOM   7717  C  CD1 . TYR D 1 363 ? 128.428 123.738 131.926 1.00 21.08  ? 356 TYR B CD1 1 
ATOM   7718  C  CD2 . TYR D 1 363 ? 130.581 122.815 131.535 1.00 21.08  ? 356 TYR B CD2 1 
ATOM   7719  C  CE1 . TYR D 1 363 ? 128.481 124.385 130.710 1.00 21.08  ? 356 TYR B CE1 1 
ATOM   7720  C  CE2 . TYR D 1 363 ? 130.642 123.457 130.318 1.00 21.08  ? 356 TYR B CE2 1 
ATOM   7721  C  CZ  . TYR D 1 363 ? 129.591 124.240 129.911 1.00 21.08  ? 356 TYR B CZ  1 
ATOM   7722  O  OH  . TYR D 1 363 ? 129.650 124.880 128.696 1.00 21.08  ? 356 TYR B OH  1 
ATOM   7723  N  N   . ILE D 1 364 ? 132.251 122.897 134.878 1.00 23.40  ? 357 ILE B N   1 
ATOM   7724  C  CA  . ILE D 1 364 ? 133.611 123.247 134.493 1.00 23.40  ? 357 ILE B CA  1 
ATOM   7725  C  C   . ILE D 1 364 ? 134.167 122.095 133.670 1.00 23.40  ? 357 ILE B C   1 
ATOM   7726  O  O   . ILE D 1 364 ? 134.026 120.928 134.054 1.00 23.40  ? 357 ILE B O   1 
ATOM   7727  C  CB  . ILE D 1 364 ? 134.505 123.541 135.711 1.00 23.40  ? 357 ILE B CB  1 
ATOM   7728  C  CG1 . ILE D 1 364 ? 134.450 122.395 136.719 1.00 23.40  ? 357 ILE B CG1 1 
ATOM   7729  C  CG2 . ILE D 1 364 ? 134.086 124.833 136.370 1.00 23.40  ? 357 ILE B CG2 1 
ATOM   7730  C  CD1 . ILE D 1 364 ? 135.336 122.608 137.917 1.00 23.40  ? 357 ILE B CD1 1 
ATOM   7731  N  N   . GLN D 1 365 ? 134.778 122.415 132.535 1.00 25.13  ? 358 GLN B N   1 
ATOM   7732  C  CA  . GLN D 1 365 ? 135.201 121.392 131.595 1.00 25.13  ? 358 GLN B CA  1 
ATOM   7733  C  C   . GLN D 1 365 ? 136.616 121.654 131.103 1.00 25.13  ? 358 GLN B C   1 
ATOM   7734  O  O   . GLN D 1 365 ? 137.095 122.789 131.073 1.00 25.13  ? 358 GLN B O   1 
ATOM   7735  C  CB  . GLN D 1 365 ? 134.232 121.294 130.409 1.00 25.13  ? 358 GLN B CB  1 
ATOM   7736  C  CG  . GLN D 1 365 ? 134.569 122.156 129.215 1.00 25.13  ? 358 GLN B CG  1 
ATOM   7737  C  CD  . GLN D 1 365 ? 133.707 121.825 128.015 1.00 25.13  ? 358 GLN B CD  1 
ATOM   7738  O  OE1 . GLN D 1 365 ? 133.618 120.670 127.603 1.00 25.13  ? 358 GLN B OE1 1 
ATOM   7739  N  NE2 . GLN D 1 365 ? 133.053 122.836 127.458 1.00 25.13  ? 358 GLN B NE2 1 
ATOM   7740  N  N   . ALA D 1 366 ? 137.277 120.565 130.728 1.00 30.07  ? 359 ALA B N   1 
ATOM   7741  C  CA  . ALA D 1 366 ? 138.628 120.557 130.193 1.00 30.07  ? 359 ALA B CA  1 
ATOM   7742  C  C   . ALA D 1 366 ? 138.711 119.413 129.196 1.00 30.07  ? 359 ALA B C   1 
ATOM   7743  O  O   . ALA D 1 366 ? 137.890 118.489 129.246 1.00 30.07  ? 359 ALA B O   1 
ATOM   7744  C  CB  . ALA D 1 366 ? 139.665 120.394 131.312 1.00 30.07  ? 359 ALA B CB  1 
ATOM   7745  N  N   . PRO D 1 367 ? 139.699 119.435 128.277 1.00 32.22  ? 360 PRO B N   1 
ATOM   7746  C  CA  . PRO D 1 367 ? 139.706 118.458 127.174 1.00 32.22  ? 360 PRO B CA  1 
ATOM   7747  C  C   . PRO D 1 367 ? 139.545 117.002 127.588 1.00 32.22  ? 360 PRO B C   1 
ATOM   7748  O  O   . PRO D 1 367 ? 139.148 116.172 126.765 1.00 32.22  ? 360 PRO B O   1 
ATOM   7749  C  CB  . PRO D 1 367 ? 141.073 118.688 126.523 1.00 32.22  ? 360 PRO B CB  1 
ATOM   7750  C  CG  . PRO D 1 367 ? 141.390 120.094 126.816 1.00 32.22  ? 360 PRO B CG  1 
ATOM   7751  C  CD  . PRO D 1 367 ? 140.834 120.370 128.177 1.00 32.22  ? 360 PRO B CD  1 
ATOM   7752  N  N   . HIS D 1 368 ? 139.840 116.671 128.845 1.00 35.97  ? 361 HIS B N   1 
ATOM   7753  C  CA  . HIS D 1 368 ? 139.773 115.290 129.298 1.00 35.97  ? 361 HIS B CA  1 
ATOM   7754  C  C   . HIS D 1 368 ? 138.631 114.998 130.264 1.00 35.97  ? 361 HIS B C   1 
ATOM   7755  O  O   . HIS D 1 368 ? 138.355 113.820 130.516 1.00 35.97  ? 361 HIS B O   1 
ATOM   7756  C  CB  . HIS D 1 368 ? 141.101 114.877 129.952 1.00 35.97  ? 361 HIS B CB  1 
ATOM   7757  C  CG  . HIS D 1 368 ? 141.463 115.686 131.157 1.00 35.97  ? 361 HIS B CG  1 
ATOM   7758  N  ND1 . HIS D 1 368 ? 140.886 115.482 132.391 1.00 35.97  ? 361 HIS B ND1 1 
ATOM   7759  C  CD2 . HIS D 1 368 ? 142.336 116.708 131.314 1.00 35.97  ? 361 HIS B CD2 1 
ATOM   7760  C  CE1 . HIS D 1 368 ? 141.392 116.340 133.259 1.00 35.97  ? 361 HIS B CE1 1 
ATOM   7761  N  NE2 . HIS D 1 368 ? 142.274 117.095 132.630 1.00 35.97  ? 361 HIS B NE2 1 
ATOM   7762  N  N   . LYS D 1 369 ? 137.955 116.014 130.803 1.00 33.51  ? 362 LYS B N   1 
ATOM   7763  C  CA  . LYS D 1 369 ? 136.881 115.747 131.751 1.00 33.51  ? 362 LYS B CA  1 
ATOM   7764  C  C   . LYS D 1 369 ? 136.010 116.979 131.935 1.00 33.51  ? 362 LYS B C   1 
ATOM   7765  O  O   . LYS D 1 369 ? 136.517 118.098 132.016 1.00 33.51  ? 362 LYS B O   1 
ATOM   7766  C  CB  . LYS D 1 369 ? 137.432 115.300 133.108 1.00 33.51  ? 362 LYS B CB  1 
ATOM   7767  C  CG  . LYS D 1 369 ? 136.420 114.549 133.948 1.00 33.51  ? 362 LYS B CG  1 
ATOM   7768  C  CD  . LYS D 1 369 ? 137.055 113.947 135.183 1.00 33.51  ? 362 LYS B CD  1 
ATOM   7769  C  CE  . LYS D 1 369 ? 136.108 112.968 135.848 1.00 33.51  ? 362 LYS B CE  1 
ATOM   7770  N  NZ  . LYS D 1 369 ? 136.684 111.601 135.933 1.00 33.51  ? 362 LYS B NZ  1 
ATOM   7771  N  N   . THR D 1 370 ? 134.694 116.750 132.014 1.00 28.82  ? 363 THR B N   1 
ATOM   7772  C  CA  . THR D 1 370 ? 133.731 117.853 132.273 1.00 28.82  ? 363 THR B CA  1 
ATOM   7773  C  C   . THR D 1 370 ? 132.882 117.455 133.484 1.00 28.82  ? 363 THR B C   1 
ATOM   7774  O  O   . THR D 1 370 ? 132.244 116.385 133.427 1.00 28.82  ? 363 THR B O   1 
ATOM   7775  C  CB  . THR D 1 370 ? 132.886 118.162 131.030 1.00 28.82  ? 363 THR B CB  1 
ATOM   7776  O  OG1 . THR D 1 370 ? 132.146 119.356 131.290 1.00 28.82  ? 363 THR B OG1 1 
ATOM   7777  C  CG2 . THR D 1 370 ? 131.938 117.042 130.660 1.00 28.82  ? 363 THR B CG2 1 
ATOM   7778  N  N   . LEU D 1 371 ? 132.888 118.266 134.543 1.00 27.61  ? 364 LEU B N   1 
ATOM   7779  C  CA  . LEU D 1 371 ? 132.168 117.937 135.763 1.00 27.61  ? 364 LEU B CA  1 
ATOM   7780  C  C   . LEU D 1 371 ? 131.368 119.134 136.257 1.00 27.61  ? 364 LEU B C   1 
ATOM   7781  O  O   . LEU D 1 371 ? 131.825 120.282 136.137 1.00 27.61  ? 364 LEU B O   1 
ATOM   7782  C  CB  . LEU D 1 371 ? 133.120 117.448 136.867 1.00 27.61  ? 364 LEU B CB  1 
ATOM   7783  C  CG  . LEU D 1 371 ? 134.208 118.376 137.405 1.00 27.61  ? 364 LEU B CG  1 
ATOM   7784  C  CD1 . LEU D 1 371 ? 134.555 118.018 138.833 1.00 27.61  ? 364 LEU B CD1 1 
ATOM   7785  C  CD2 . LEU D 1 371 ? 135.441 118.271 136.544 1.00 27.61  ? 364 LEU B CD2 1 
ATOM   7786  N  N   . PRO D 1 372 ? 130.174 118.904 136.788 1.00 25.63  ? 365 PRO B N   1 
ATOM   7787  C  CA  . PRO D 1 372 ? 129.366 120.014 137.297 1.00 25.63  ? 365 PRO B CA  1 
ATOM   7788  C  C   . PRO D 1 372 ? 129.908 120.560 138.609 1.00 25.63  ? 365 PRO B C   1 
ATOM   7789  O  O   . PRO D 1 372 ? 130.711 119.932 139.302 1.00 25.63  ? 365 PRO B O   1 
ATOM   7790  C  CB  . PRO D 1 372 ? 127.980 119.390 137.486 1.00 25.63  ? 365 PRO B CB  1 
ATOM   7791  C  CG  . PRO D 1 372 ? 128.239 117.938 137.624 1.00 25.63  ? 365 PRO B CG  1 
ATOM   7792  C  CD  . PRO D 1 372 ? 129.420 117.641 136.759 1.00 25.63  ? 365 PRO B CD  1 
ATOM   7793  N  N   . VAL D 1 373 ? 129.448 121.764 138.936 1.00 29.03  ? 366 VAL B N   1 
ATOM   7794  C  CA  . VAL D 1 373 ? 129.851 122.477 140.143 1.00 29.03  ? 366 VAL B CA  1 
ATOM   7795  C  C   . VAL D 1 373 ? 128.647 123.245 140.671 1.00 29.03  ? 366 VAL B C   1 
ATOM   7796  O  O   . VAL D 1 373 ? 127.931 123.906 139.912 1.00 29.03  ? 366 VAL B O   1 
ATOM   7797  C  CB  . VAL D 1 373 ? 131.040 123.420 139.866 1.00 29.03  ? 366 VAL B CB  1 
ATOM   7798  C  CG1 . VAL D 1 373 ? 131.113 124.512 140.911 1.00 29.03  ? 366 VAL B CG1 1 
ATOM   7799  C  CG2 . VAL D 1 373 ? 132.332 122.639 139.843 1.00 29.03  ? 366 VAL B CG2 1 
ATOM   7800  N  N   . VAL D 1 374 ? 128.428 123.159 141.981 1.00 34.23  ? 367 VAL B N   1 
ATOM   7801  C  CA  . VAL D 1 374 ? 127.328 123.846 142.644 1.00 34.23  ? 367 VAL B CA  1 
ATOM   7802  C  C   . VAL D 1 374 ? 127.855 125.130 143.273 1.00 34.23  ? 367 VAL B C   1 
ATOM   7803  O  O   . VAL D 1 374 ? 128.904 125.131 143.932 1.00 34.23  ? 367 VAL B O   1 
ATOM   7804  C  CB  . VAL D 1 374 ? 126.651 122.943 143.690 1.00 34.23  ? 367 VAL B CB  1 
ATOM   7805  C  CG1 . VAL D 1 374 ? 127.660 122.409 144.683 1.00 34.23  ? 367 VAL B CG1 1 
ATOM   7806  C  CG2 . VAL D 1 374 ? 125.552 123.696 144.408 1.00 34.23  ? 367 VAL B CG2 1 
ATOM   7807  N  N   . PHE D 1 375 ? 127.132 126.223 143.055 1.00 38.72  ? 368 PHE B N   1 
ATOM   7808  C  CA  . PHE D 1 375 ? 127.450 127.538 143.584 1.00 38.72  ? 368 PHE B CA  1 
ATOM   7809  C  C   . PHE D 1 375 ? 126.468 127.836 144.706 1.00 38.72  ? 368 PHE B C   1 
ATOM   7810  O  O   . PHE D 1 375 ? 125.253 127.865 144.476 1.00 38.72  ? 368 PHE B O   1 
ATOM   7811  C  CB  . PHE D 1 375 ? 127.356 128.590 142.482 1.00 38.72  ? 368 PHE B CB  1 
ATOM   7812  C  CG  . PHE D 1 375 ? 128.193 129.808 142.721 1.00 38.72  ? 368 PHE B CG  1 
ATOM   7813  C  CD1 . PHE D 1 375 ? 129.569 129.737 142.685 1.00 38.72  ? 368 PHE B CD1 1 
ATOM   7814  C  CD2 . PHE D 1 375 ? 127.601 131.033 142.953 1.00 38.72  ? 368 PHE B CD2 1 
ATOM   7815  C  CE1 . PHE D 1 375 ? 130.335 130.859 142.897 1.00 38.72  ? 368 PHE B CE1 1 
ATOM   7816  C  CE2 . PHE D 1 375 ? 128.358 132.159 143.162 1.00 38.72  ? 368 PHE B CE2 1 
ATOM   7817  C  CZ  . PHE D 1 375 ? 129.728 132.075 143.133 1.00 38.72  ? 368 PHE B CZ  1 
ATOM   7818  N  N   . ASP D 1 376 ? 126.997 128.051 145.908 1.00 46.30  ? 369 ASP B N   1 
ATOM   7819  C  CA  . ASP D 1 376 ? 126.196 128.250 147.109 1.00 46.30  ? 369 ASP B CA  1 
ATOM   7820  C  C   . ASP D 1 376 ? 126.095 129.743 147.394 1.00 46.30  ? 369 ASP B C   1 
ATOM   7821  O  O   . ASP D 1 376 ? 127.116 130.429 147.508 1.00 46.30  ? 369 ASP B O   1 
ATOM   7822  C  CB  . ASP D 1 376 ? 126.816 127.511 148.296 1.00 46.30  ? 369 ASP B CB  1 
ATOM   7823  C  CG  . ASP D 1 376 ? 125.965 127.591 149.554 1.00 46.30  ? 369 ASP B CG  1 
ATOM   7824  O  OD1 . ASP D 1 376 ? 124.826 128.098 149.488 1.00 46.30  ? 369 ASP B OD1 1 
ATOM   7825  O  OD2 . ASP D 1 376 ? 126.440 127.146 150.619 1.00 46.30  ? 369 ASP B OD2 1 
ATOM   7826  N  N   . SER D 1 377 ? 124.867 130.238 147.510 1.00 48.94  ? 370 SER B N   1 
ATOM   7827  C  CA  . SER D 1 377 ? 124.650 131.647 147.786 1.00 48.94  ? 370 SER B CA  1 
ATOM   7828  C  C   . SER D 1 377 ? 125.086 131.989 149.209 1.00 48.94  ? 370 SER B C   1 
ATOM   7829  O  O   . SER D 1 377 ? 125.095 131.126 150.089 1.00 48.94  ? 370 SER B O   1 
ATOM   7830  C  CB  . SER D 1 377 ? 123.178 132.001 147.606 1.00 48.94  ? 370 SER B CB  1 
ATOM   7831  O  OG  . SER D 1 377 ? 122.834 133.154 148.352 1.00 48.94  ? 370 SER B OG  1 
ATOM   7832  N  N   . PRO D 1 378 ? 125.462 133.245 149.457 1.00 51.93  ? 371 PRO B N   1 
ATOM   7833  C  CA  . PRO D 1 378 ? 125.718 133.669 150.842 1.00 51.93  ? 371 PRO B CA  1 
ATOM   7834  C  C   . PRO D 1 378 ? 124.487 133.601 151.729 1.00 51.93  ? 371 PRO B C   1 
ATOM   7835  O  O   . PRO D 1 378 ? 124.630 133.621 152.957 1.00 51.93  ? 371 PRO B O   1 
ATOM   7836  C  CB  . PRO D 1 378 ? 126.222 135.111 150.689 1.00 51.93  ? 371 PRO B CB  1 
ATOM   7837  C  CG  . PRO D 1 378 ? 125.817 135.528 149.317 1.00 51.93  ? 371 PRO B CG  1 
ATOM   7838  C  CD  . PRO D 1 378 ? 125.814 134.291 148.486 1.00 51.93  ? 371 PRO B CD  1 
ATOM   7839  N  N   . ARG D 1 379 ? 123.287 133.544 151.154 1.00 58.73  ? 372 ARG B N   1 
ATOM   7840  C  CA  . ARG D 1 379 ? 122.086 133.334 151.951 1.00 58.73  ? 372 ARG B CA  1 
ATOM   7841  C  C   . ARG D 1 379 ? 122.162 131.988 152.664 1.00 58.73  ? 372 ARG B C   1 
ATOM   7842  O  O   . ARG D 1 379 ? 122.491 130.966 152.055 1.00 58.73  ? 372 ARG B O   1 
ATOM   7843  C  CB  . ARG D 1 379 ? 120.845 133.404 151.063 1.00 58.73  ? 372 ARG B CB  1 
ATOM   7844  C  CG  . ARG D 1 379 ? 119.700 132.524 151.526 1.00 58.73  ? 372 ARG B CG  1 
ATOM   7845  C  CD  . ARG D 1 379 ? 118.738 132.221 150.395 1.00 58.73  ? 372 ARG B CD  1 
ATOM   7846  N  NE  . ARG D 1 379 ? 118.082 130.933 150.583 1.00 58.73  ? 372 ARG B NE  1 
ATOM   7847  C  CZ  . ARG D 1 379 ? 116.789 130.781 150.823 1.00 58.73  ? 372 ARG B CZ  1 
ATOM   7848  N  NH1 . ARG D 1 379 ? 115.977 131.821 150.914 1.00 58.73  ? 372 ARG B NH1 1 
ATOM   7849  N  NH2 . ARG D 1 379 ? 116.297 129.556 150.978 1.00 58.73  ? 372 ARG B NH2 1 
ATOM   7850  N  N   . ASN D 1 380 ? 121.856 131.990 153.959 1.00 61.80  ? 373 ASN B N   1 
ATOM   7851  C  CA  . ASN D 1 380 ? 122.038 130.834 154.834 1.00 61.80  ? 373 ASN B CA  1 
ATOM   7852  C  C   . ASN D 1 380 ? 120.768 130.543 155.622 1.00 61.80  ? 373 ASN B C   1 
ATOM   7853  O  O   . ASN D 1 380 ? 120.775 130.430 156.849 1.00 61.80  ? 373 ASN B O   1 
ATOM   7854  C  CB  . ASN D 1 380 ? 123.221 131.029 155.779 1.00 61.80  ? 373 ASN B CB  1 
ATOM   7855  C  CG  . ASN D 1 380 ? 124.556 131.005 155.061 1.00 61.80  ? 373 ASN B CG  1 
ATOM   7856  O  OD1 . ASN D 1 380 ? 124.619 131.006 153.834 1.00 61.80  ? 373 ASN B OD1 1 
ATOM   7857  N  ND2 . ASN D 1 380 ? 125.635 130.980 155.829 1.00 61.80  ? 373 ASN B ND2 1 
ATOM   7858  N  N   . ARG D 1 381 ? 119.649 130.415 154.917 1.00 65.24  ? 374 ARG B N   1 
ATOM   7859  C  CA  . ARG D 1 381 ? 118.398 130.011 155.543 1.00 65.24  ? 374 ARG B CA  1 
ATOM   7860  C  C   . ARG D 1 381 ? 118.441 128.508 155.824 1.00 65.24  ? 374 ARG B C   1 
ATOM   7861  O  O   . ARG D 1 381 ? 119.501 127.876 155.798 1.00 65.24  ? 374 ARG B O   1 
ATOM   7862  C  CB  . ARG D 1 381 ? 117.212 130.397 154.666 1.00 65.24  ? 374 ARG B CB  1 
ATOM   7863  C  CG  . ARG D 1 381 ? 117.173 131.867 154.295 1.00 65.24  ? 374 ARG B CG  1 
ATOM   7864  C  CD  . ARG D 1 381 ? 116.413 132.678 155.337 1.00 65.24  ? 374 ARG B CD  1 
ATOM   7865  N  NE  . ARG D 1 381 ? 115.922 133.950 154.817 1.00 65.24  ? 374 ARG B NE  1 
ATOM   7866  C  CZ  . ARG D 1 381 ? 115.030 134.080 153.844 1.00 65.24  ? 374 ARG B CZ  1 
ATOM   7867  N  NH1 . ARG D 1 381 ? 114.458 133.028 153.279 1.00 65.24  ? 374 ARG B NH1 1 
ATOM   7868  N  NH2 . ARG D 1 381 ? 114.690 135.299 153.436 1.00 65.24  ? 374 ARG B NH2 1 
ATOM   7869  N  N   . GLY D 1 382 ? 117.277 127.918 156.105 1.00 68.75  ? 375 GLY B N   1 
ATOM   7870  C  CA  . GLY D 1 382 ? 117.210 126.539 156.564 1.00 68.75  ? 375 GLY B CA  1 
ATOM   7871  C  C   . GLY D 1 382 ? 117.820 125.517 155.623 1.00 68.75  ? 375 GLY B C   1 
ATOM   7872  O  O   . GLY D 1 382 ? 118.058 124.377 156.037 1.00 68.75  ? 375 GLY B O   1 
ATOM   7873  N  N   . LEU D 1 383 ? 118.079 125.889 154.368 1.00 63.08  ? 376 LEU B N   1 
ATOM   7874  C  CA  . LEU D 1 383 ? 118.660 124.977 153.390 1.00 63.08  ? 376 LEU B CA  1 
ATOM   7875  C  C   . LEU D 1 383 ? 120.166 125.145 153.242 1.00 63.08  ? 376 LEU B C   1 
ATOM   7876  O  O   . LEU D 1 383 ? 120.696 124.977 152.137 1.00 63.08  ? 376 LEU B O   1 
ATOM   7877  C  CB  . LEU D 1 383 ? 117.981 125.150 152.033 1.00 63.08  ? 376 LEU B CB  1 
ATOM   7878  C  CG  . LEU D 1 383 ? 116.736 124.301 151.795 1.00 63.08  ? 376 LEU B CG  1 
ATOM   7879  C  CD1 . LEU D 1 383 ? 115.884 124.904 150.696 1.00 63.08  ? 376 LEU B CD1 1 
ATOM   7880  C  CD2 . LEU D 1 383 ? 117.127 122.877 151.456 1.00 63.08  ? 376 LEU B CD2 1 
ATOM   7881  N  N   . LYS D 1 384 ? 120.876 125.474 154.321 1.00 57.48  ? 377 LYS B N   1 
ATOM   7882  C  CA  . LYS D 1 384 ? 122.323 125.624 154.227 1.00 57.48  ? 377 LYS B CA  1 
ATOM   7883  C  C   . LYS D 1 384 ? 123.053 124.287 154.258 1.00 57.48  ? 377 LYS B C   1 
ATOM   7884  O  O   . LYS D 1 384 ? 124.267 124.256 154.030 1.00 57.48  ? 377 LYS B O   1 
ATOM   7885  C  CB  . LYS D 1 384 ? 122.832 126.527 155.351 1.00 57.48  ? 377 LYS B CB  1 
ATOM   7886  C  CG  . LYS D 1 384 ? 122.203 126.257 156.705 1.00 57.48  ? 377 LYS B CG  1 
ATOM   7887  C  CD  . LYS D 1 384 ? 122.876 127.073 157.795 1.00 57.48  ? 377 LYS B CD  1 
ATOM   7888  C  CE  . LYS D 1 384 ? 122.115 126.973 159.104 1.00 57.48  ? 377 LYS B CE  1 
ATOM   7889  N  NZ  . LYS D 1 384 ? 122.385 125.685 159.798 1.00 57.48  ? 377 LYS B NZ  1 
ATOM   7890  N  N   . GLU D 1 385 ? 122.349 123.188 154.533 1.00 60.90  ? 378 GLU B N   1 
ATOM   7891  C  CA  . GLU D 1 385 ? 122.980 121.877 154.617 1.00 60.90  ? 378 GLU B CA  1 
ATOM   7892  C  C   . GLU D 1 385 ? 122.813 121.037 153.360 1.00 60.90  ? 378 GLU B C   1 
ATOM   7893  O  O   . GLU D 1 385 ? 123.633 120.142 153.118 1.00 60.90  ? 378 GLU B O   1 
ATOM   7894  C  CB  . GLU D 1 385 ? 122.429 121.101 155.815 1.00 60.90  ? 378 GLU B CB  1 
ATOM   7895  C  CG  . GLU D 1 385 ? 122.804 121.698 157.155 1.00 60.90  ? 378 GLU B CG  1 
ATOM   7896  C  CD  . GLU D 1 385 ? 122.180 120.946 158.313 1.00 60.90  ? 378 GLU B CD  1 
ATOM   7897  O  OE1 . GLU D 1 385 ? 121.312 120.083 158.064 1.00 60.90  ? 378 GLU B OE1 1 
ATOM   7898  O  OE2 . GLU D 1 385 ? 122.562 121.212 159.472 1.00 60.90  ? 378 GLU B OE2 1 
ATOM   7899  N  N   . PHE D 1 386 ? 121.773 121.284 152.567 1.00 54.55  ? 379 PHE B N   1 
ATOM   7900  C  CA  . PHE D 1 386 ? 121.575 120.500 151.349 1.00 54.55  ? 379 PHE B CA  1 
ATOM   7901  C  C   . PHE D 1 386 ? 122.721 120.640 150.355 1.00 54.55  ? 379 PHE B C   1 
ATOM   7902  O  O   . PHE D 1 386 ? 123.292 119.605 149.964 1.00 54.55  ? 379 PHE B O   1 
ATOM   7903  C  CB  . PHE D 1 386 ? 120.230 120.871 150.719 1.00 54.55  ? 379 PHE B CB  1 
ATOM   7904  C  CG  . PHE D 1 386 ? 119.864 120.031 149.532 1.00 54.55  ? 379 PHE B CG  1 
ATOM   7905  C  CD1 . PHE D 1 386 ? 119.508 118.706 149.684 1.00 54.55  ? 379 PHE B CD1 1 
ATOM   7906  C  CD2 . PHE D 1 386 ? 119.866 120.578 148.262 1.00 54.55  ? 379 PHE B CD2 1 
ATOM   7907  C  CE1 . PHE D 1 386 ? 119.163 117.940 148.591 1.00 54.55  ? 379 PHE B CE1 1 
ATOM   7908  C  CE2 . PHE D 1 386 ? 119.525 119.817 147.166 1.00 54.55  ? 379 PHE B CE2 1 
ATOM   7909  C  CZ  . PHE D 1 386 ? 119.173 118.496 147.330 1.00 54.55  ? 379 PHE B CZ  1 
ATOM   7910  N  N   . PRO D 1 387 ? 123.130 121.841 149.925 1.00 49.09  ? 380 PRO B N   1 
ATOM   7911  C  CA  . PRO D 1 387 ? 124.210 121.930 148.932 1.00 49.09  ? 380 PRO B CA  1 
ATOM   7912  C  C   . PRO D 1 387 ? 125.556 121.462 149.443 1.00 49.09  ? 380 PRO B C   1 
ATOM   7913  O  O   . PRO D 1 387 ? 126.439 121.172 148.631 1.00 49.09  ? 380 PRO B O   1 
ATOM   7914  C  CB  . PRO D 1 387 ? 124.249 123.429 148.588 1.00 49.09  ? 380 PRO B CB  1 
ATOM   7915  C  CG  . PRO D 1 387 ? 122.966 123.974 149.080 1.00 49.09  ? 380 PRO B CG  1 
ATOM   7916  C  CD  . PRO D 1 387 ? 122.660 123.184 150.299 1.00 49.09  ? 380 PRO B CD  1 
ATOM   7917  N  N   . ILE D 1 388 ? 125.741 121.368 150.757 1.00 49.47  ? 381 ILE B N   1 
ATOM   7918  C  CA  . ILE D 1 388 ? 127.024 121.005 151.334 1.00 49.47  ? 381 ILE B CA  1 
ATOM   7919  C  C   . ILE D 1 388 ? 127.089 119.532 151.708 1.00 49.47  ? 381 ILE B C   1 
ATOM   7920  O  O   . ILE D 1 388 ? 128.188 118.981 151.821 1.00 49.47  ? 381 ILE B O   1 
ATOM   7921  C  CB  . ILE D 1 388 ? 127.352 121.891 152.554 1.00 49.47  ? 381 ILE B CB  1 
ATOM   7922  C  CG1 . ILE D 1 388 ? 126.319 121.705 153.656 1.00 49.47  ? 381 ILE B CG1 1 
ATOM   7923  C  CG2 . ILE D 1 388 ? 127.413 123.349 152.160 1.00 49.47  ? 381 ILE B CG2 1 
ATOM   7924  C  CD1 . ILE D 1 388 ? 126.804 120.786 154.732 1.00 49.47  ? 381 ILE B CD1 1 
ATOM   7925  N  N   . LYS D 1 389 ? 125.950 118.865 151.858 1.00 51.49  ? 382 LYS B N   1 
ATOM   7926  C  CA  . LYS D 1 389 ? 125.966 117.450 152.216 1.00 51.49  ? 382 LYS B CA  1 
ATOM   7927  C  C   . LYS D 1 389 ? 125.373 116.540 151.151 1.00 51.49  ? 382 LYS B C   1 
ATOM   7928  O  O   . LYS D 1 389 ? 125.961 115.499 150.852 1.00 51.49  ? 382 LYS B O   1 
ATOM   7929  C  CB  . LYS D 1 389 ? 125.220 117.241 153.543 1.00 51.49  ? 382 LYS B CB  1 
ATOM   7930  C  CG  . LYS D 1 389 ? 125.105 115.786 153.976 1.00 51.49  ? 382 LYS B CG  1 
ATOM   7931  C  CD  . LYS D 1 389 ? 126.462 115.110 154.091 1.00 51.49  ? 382 LYS B CD  1 
ATOM   7932  C  CE  . LYS D 1 389 ? 127.030 115.231 155.496 1.00 51.49  ? 382 LYS B CE  1 
ATOM   7933  N  NZ  . LYS D 1 389 ? 127.928 114.088 155.825 1.00 51.49  ? 382 LYS B NZ  1 
ATOM   7934  N  N   . ARG D 1 390 ? 124.232 116.901 150.566 1.00 50.33  ? 383 ARG B N   1 
ATOM   7935  C  CA  . ARG D 1 390 ? 123.509 116.002 149.676 1.00 50.33  ? 383 ARG B CA  1 
ATOM   7936  C  C   . ARG D 1 390 ? 123.752 116.285 148.199 1.00 50.33  ? 383 ARG B C   1 
ATOM   7937  O  O   . ARG D 1 390 ? 123.145 115.624 147.351 1.00 50.33  ? 383 ARG B O   1 
ATOM   7938  C  CB  . ARG D 1 390 ? 122.007 116.068 149.975 1.00 50.33  ? 383 ARG B CB  1 
ATOM   7939  C  CG  . ARG D 1 390 ? 121.228 114.797 149.641 1.00 50.33  ? 383 ARG B CG  1 
ATOM   7940  C  CD  . ARG D 1 390 ? 121.843 113.559 150.276 1.00 50.33  ? 383 ARG B CD  1 
ATOM   7941  N  NE  . ARG D 1 390 ? 121.615 113.502 151.714 1.00 50.33  ? 383 ARG B NE  1 
ATOM   7942  C  CZ  . ARG D 1 390 ? 122.519 113.108 152.601 1.00 50.33  ? 383 ARG B CZ  1 
ATOM   7943  N  NH1 . ARG D 1 390 ? 123.731 112.730 152.230 1.00 50.33  ? 383 ARG B NH1 1 
ATOM   7944  N  NH2 . ARG D 1 390 ? 122.199 113.092 153.891 1.00 50.33  ? 383 ARG B NH2 1 
ATOM   7945  N  N   . VAL D 1 391 ? 124.623 117.235 147.863 1.00 46.48  ? 384 VAL B N   1 
ATOM   7946  C  CA  . VAL D 1 391 ? 124.837 117.586 146.463 1.00 46.48  ? 384 VAL B CA  1 
ATOM   7947  C  C   . VAL D 1 391 ? 126.267 117.264 146.054 1.00 46.48  ? 384 VAL B C   1 
ATOM   7948  O  O   . VAL D 1 391 ? 126.494 116.450 145.151 1.00 46.48  ? 384 VAL B O   1 
ATOM   7949  C  CB  . VAL D 1 391 ? 124.504 119.067 146.209 1.00 46.48  ? 384 VAL B CB  1 
ATOM   7950  C  CG1 . VAL D 1 391 ? 125.210 119.572 144.963 1.00 46.48  ? 384 VAL B CG1 1 
ATOM   7951  C  CG2 . VAL D 1 391 ? 123.006 119.239 146.080 1.00 46.48  ? 384 VAL B CG2 1 
ATOM   7952  N  N   . MET D 1 392 ? 127.225 117.896 146.744 1.00 43.46  ? 385 MET B N   1 
ATOM   7953  C  CA  . MET D 1 392 ? 128.662 117.689 146.422 1.00 43.46  ? 385 MET B CA  1 
ATOM   7954  C  C   . MET D 1 392 ? 129.056 116.254 146.778 1.00 43.46  ? 385 MET B C   1 
ATOM   7955  O  O   . MET D 1 392 ? 128.681 115.794 147.875 1.00 43.46  ? 385 MET B O   1 
ATOM   7956  C  CB  . MET D 1 392 ? 129.553 118.663 147.201 1.00 43.46  ? 385 MET B CB  1 
ATOM   7957  C  CG  . MET D 1 392 ? 131.037 118.393 147.017 1.00 43.46  ? 385 MET B CG  1 
ATOM   7958  S  SD  . MET D 1 392 ? 132.106 119.492 147.977 1.00 43.46  ? 385 MET B SD  1 
ATOM   7959  C  CE  . MET D 1 392 ? 132.742 118.347 149.200 1.00 43.46  ? 385 MET B CE  1 
ATOM   7960  N  N   . GLY D 1 393 ? 129.781 115.584 145.884 1.00 42.88  ? 386 GLY B N   1 
ATOM   7961  C  CA  . GLY D 1 393 ? 130.208 114.226 146.115 1.00 42.88  ? 386 GLY B CA  1 
ATOM   7962  C  C   . GLY D 1 393 ? 131.193 113.756 145.067 1.00 42.88  ? 386 GLY B C   1 
ATOM   7963  O  O   . GLY D 1 393 ? 132.111 114.481 144.675 1.00 42.88  ? 386 GLY B O   1 
ATOM   7964  N  N   . PRO D 1 394 ? 131.030 112.519 144.600 1.00 41.52  ? 387 PRO B N   1 
ATOM   7965  C  CA  . PRO D 1 394 ? 131.863 112.029 143.494 1.00 41.52  ? 387 PRO B CA  1 
ATOM   7966  C  C   . PRO D 1 394 ? 131.502 112.750 142.204 1.00 41.52  ? 387 PRO B C   1 
ATOM   7967  O  O   . PRO D 1 394 ? 130.366 112.666 141.734 1.00 41.52  ? 387 PRO B O   1 
ATOM   7968  C  CB  . PRO D 1 394 ? 131.524 110.534 143.424 1.00 41.52  ? 387 PRO B CB  1 
ATOM   7969  C  CG  . PRO D 1 394 ? 130.847 110.219 144.722 1.00 41.52  ? 387 PRO B CG  1 
ATOM   7970  C  CD  . PRO D 1 394 ? 130.146 111.471 145.130 1.00 41.52  ? 387 PRO B CD  1 
ATOM   7971  N  N   . ASP D 1 395 ? 132.478 113.464 141.640 1.00 39.80  ? 388 ASP B N   1 
ATOM   7972  C  CA  . ASP D 1 395 ? 132.298 114.216 140.397 1.00 39.80  ? 388 ASP B CA  1 
ATOM   7973  C  C   . ASP D 1 395 ? 131.183 115.251 140.530 1.00 39.80  ? 388 ASP B C   1 
ATOM   7974  O  O   . ASP D 1 395 ? 130.241 115.291 139.737 1.00 39.80  ? 388 ASP B O   1 
ATOM   7975  C  CB  . ASP D 1 395 ? 132.035 113.278 139.220 1.00 39.80  ? 388 ASP B CB  1 
ATOM   7976  C  CG  . ASP D 1 395 ? 133.305 112.837 138.537 1.00 39.80  ? 388 ASP B CG  1 
ATOM   7977  O  OD1 . ASP D 1 395 ? 134.289 112.535 139.243 1.00 39.80  ? 388 ASP B OD1 1 
ATOM   7978  O  OD2 . ASP D 1 395 ? 133.317 112.790 137.291 1.00 39.80  ? 388 ASP B OD2 1 
ATOM   7979  N  N   . PHE D 1 396 ? 131.290 116.086 141.562 1.00 35.52  ? 389 PHE B N   1 
ATOM   7980  C  CA  . PHE D 1 396 ? 130.356 117.193 141.758 1.00 35.52  ? 389 PHE B CA  1 
ATOM   7981  C  C   . PHE D 1 396 ? 131.069 118.228 142.621 1.00 35.52  ? 389 PHE B C   1 
ATOM   7982  O  O   . PHE D 1 396 ? 131.106 118.093 143.847 1.00 35.52  ? 389 PHE B O   1 
ATOM   7983  C  CB  . PHE D 1 396 ? 129.067 116.714 142.408 1.00 35.52  ? 389 PHE B CB  1 
ATOM   7984  C  CG  . PHE D 1 396 ? 127.826 117.313 141.816 1.00 35.52  ? 389 PHE B CG  1 
ATOM   7985  C  CD1 . PHE D 1 396 ? 127.745 118.670 141.568 1.00 35.52  ? 389 PHE B CD1 1 
ATOM   7986  C  CD2 . PHE D 1 396 ? 126.731 116.519 141.528 1.00 35.52  ? 389 PHE B CD2 1 
ATOM   7987  C  CE1 . PHE D 1 396 ? 126.599 119.222 141.032 1.00 35.52  ? 389 PHE B CE1 1 
ATOM   7988  C  CE2 . PHE D 1 396 ? 125.585 117.066 140.994 1.00 35.52  ? 389 PHE B CE2 1 
ATOM   7989  C  CZ  . PHE D 1 396 ? 125.519 118.420 140.746 1.00 35.52  ? 389 PHE B CZ  1 
ATOM   7990  N  N   . GLY D 1 397 ? 131.621 119.255 141.985 1.00 35.29  ? 390 GLY B N   1 
ATOM   7991  C  CA  . GLY D 1 397 ? 132.364 120.268 142.700 1.00 35.29  ? 390 GLY B CA  1 
ATOM   7992  C  C   . GLY D 1 397 ? 131.464 121.243 143.434 1.00 35.29  ? 390 GLY B C   1 
ATOM   7993  O  O   . GLY D 1 397 ? 130.256 121.315 143.220 1.00 35.29  ? 390 GLY B O   1 
ATOM   7994  N  N   . TYR D 1 398 ? 132.085 122.032 144.308 1.00 38.29  ? 391 TYR B N   1 
ATOM   7995  C  CA  . TYR D 1 398 ? 131.343 122.997 145.116 1.00 38.29  ? 391 TYR B CA  1 
ATOM   7996  C  C   . TYR D 1 398 ? 132.213 124.235 145.270 1.00 38.29  ? 391 TYR B C   1 
ATOM   7997  O  O   . TYR D 1 398 ? 133.362 124.127 145.709 1.00 38.29  ? 391 TYR B O   1 
ATOM   7998  C  CB  . TYR D 1 398 ? 130.984 122.397 146.472 1.00 38.29  ? 391 TYR B CB  1 
ATOM   7999  C  CG  . TYR D 1 398 ? 130.563 123.396 147.530 1.00 38.29  ? 391 TYR B CG  1 
ATOM   8000  C  CD1 . TYR D 1 398 ? 129.221 123.643 147.779 1.00 38.29  ? 391 TYR B CD1 1 
ATOM   8001  C  CD2 . TYR D 1 398 ? 131.504 124.065 148.303 1.00 38.29  ? 391 TYR B CD2 1 
ATOM   8002  C  CE1 . TYR D 1 398 ? 128.829 124.545 148.745 1.00 38.29  ? 391 TYR B CE1 1 
ATOM   8003  C  CE2 . TYR D 1 398 ? 131.120 124.969 149.268 1.00 38.29  ? 391 TYR B CE2 1 
ATOM   8004  C  CZ  . TYR D 1 398 ? 129.782 125.203 149.486 1.00 38.29  ? 391 TYR B CZ  1 
ATOM   8005  O  OH  . TYR D 1 398 ? 129.393 126.101 150.450 1.00 38.29  ? 391 TYR B OH  1 
ATOM   8006  N  N   . VAL D 1 399 ? 131.676 125.400 144.916 1.00 37.82  ? 392 VAL B N   1 
ATOM   8007  C  CA  . VAL D 1 399 ? 132.390 126.660 145.091 1.00 37.82  ? 392 VAL B CA  1 
ATOM   8008  C  C   . VAL D 1 399 ? 131.396 127.738 145.497 1.00 37.82  ? 392 VAL B C   1 
ATOM   8009  O  O   . VAL D 1 399 ? 130.248 127.735 145.041 1.00 37.82  ? 392 VAL B O   1 
ATOM   8010  C  CB  . VAL D 1 399 ? 133.167 127.060 143.821 1.00 37.82  ? 392 VAL B CB  1 
ATOM   8011  C  CG1 . VAL D 1 399 ? 132.249 127.653 142.775 1.00 37.82  ? 392 VAL B CG1 1 
ATOM   8012  C  CG2 . VAL D 1 399 ? 134.272 128.033 144.174 1.00 37.82  ? 392 VAL B CG2 1 
ATOM   8013  N  N   . THR D 1 400 ? 131.825 128.637 146.382 1.00 41.07  ? 393 THR B N   1 
ATOM   8014  C  CA  . THR D 1 400 ? 130.984 129.712 146.886 1.00 41.07  ? 393 THR B CA  1 
ATOM   8015  C  C   . THR D 1 400 ? 131.837 130.938 147.173 1.00 41.07  ? 393 THR B C   1 
ATOM   8016  O  O   . THR D 1 400 ? 133.047 130.833 147.384 1.00 41.07  ? 393 THR B O   1 
ATOM   8017  C  CB  . THR D 1 400 ? 130.240 129.300 148.158 1.00 41.07  ? 393 THR B CB  1 
ATOM   8018  O  OG1 . THR D 1 400 ? 129.668 130.462 148.771 1.00 41.07  ? 393 THR B OG1 1 
ATOM   8019  C  CG2 . THR D 1 400 ? 131.192 128.638 149.135 1.00 41.07  ? 393 THR B CG2 1 
ATOM   8020  N  N   . ARG D 1 401 ? 131.191 132.104 147.188 1.00 41.42  ? 394 ARG B N   1 
ATOM   8021  C  CA  . ARG D 1 401 ? 131.878 133.369 147.407 1.00 41.42  ? 394 ARG B CA  1 
ATOM   8022  C  C   . ARG D 1 401 ? 131.002 134.293 148.240 1.00 41.42  ? 394 ARG B C   1 
ATOM   8023  O  O   . ARG D 1 401 ? 129.774 134.182 148.235 1.00 41.42  ? 394 ARG B O   1 
ATOM   8024  C  CB  . ARG D 1 401 ? 132.235 134.051 146.080 1.00 41.42  ? 394 ARG B CB  1 
ATOM   8025  C  CG  . ARG D 1 401 ? 133.413 133.425 145.360 1.00 41.42  ? 394 ARG B CG  1 
ATOM   8026  C  CD  . ARG D 1 401 ? 134.621 133.339 146.272 1.00 41.42  ? 394 ARG B CD  1 
ATOM   8027  N  NE  . ARG D 1 401 ? 135.851 133.746 145.605 1.00 41.42  ? 394 ARG B NE  1 
ATOM   8028  C  CZ  . ARG D 1 401 ? 136.504 133.007 144.719 1.00 41.42  ? 394 ARG B CZ  1 
ATOM   8029  N  NH1 . ARG D 1 401 ? 136.075 131.805 144.374 1.00 41.42  ? 394 ARG B NH1 1 
ATOM   8030  N  NH2 . ARG D 1 401 ? 137.617 133.484 144.172 1.00 41.42  ? 394 ARG B NH2 1 
ATOM   8031  N  N   . GLY D 1 402 ? 131.648 135.209 148.960 1.00 48.96  ? 395 GLY B N   1 
ATOM   8032  C  CA  . GLY D 1 402 ? 130.947 136.231 149.700 1.00 48.96  ? 395 GLY B CA  1 
ATOM   8033  C  C   . GLY D 1 402 ? 131.049 136.064 151.202 1.00 48.96  ? 395 GLY B C   1 
ATOM   8034  O  O   . GLY D 1 402 ? 131.685 135.134 151.708 1.00 48.96  ? 395 GLY B O   1 
ATOM   8035  N  N   . PRO D 1 403 ? 130.423 136.979 151.951 1.00 53.33  ? 396 PRO B N   1 
ATOM   8036  C  CA  . PRO D 1 403 ? 130.398 136.848 153.412 1.00 53.33  ? 396 PRO B CA  1 
ATOM   8037  C  C   . PRO D 1 403 ? 129.254 135.967 153.883 1.00 53.33  ? 396 PRO B C   1 
ATOM   8038  O  O   . PRO D 1 403 ? 128.098 136.186 153.508 1.00 53.33  ? 396 PRO B O   1 
ATOM   8039  C  CB  . PRO D 1 403 ? 130.227 138.296 153.882 1.00 53.33  ? 396 PRO B CB  1 
ATOM   8040  C  CG  . PRO D 1 403 ? 129.443 138.942 152.785 1.00 53.33  ? 396 PRO B CG  1 
ATOM   8041  C  CD  . PRO D 1 403 ? 129.751 138.208 151.496 1.00 53.33  ? 396 PRO B CD  1 
ATOM   8042  N  N   . GLN D 1 404 ? 129.561 134.968 154.707 1.00 58.65  ? 397 GLN B N   1 
ATOM   8043  C  CA  . GLN D 1 404 ? 128.557 133.998 155.124 1.00 58.65  ? 397 GLN B CA  1 
ATOM   8044  C  C   . GLN D 1 404 ? 127.844 134.389 156.411 1.00 58.65  ? 397 GLN B C   1 
ATOM   8045  O  O   . GLN D 1 404 ? 126.677 134.025 156.597 1.00 58.65  ? 397 GLN B O   1 
ATOM   8046  C  CB  . GLN D 1 404 ? 129.201 132.621 155.298 1.00 58.65  ? 397 GLN B CB  1 
ATOM   8047  C  CG  . GLN D 1 404 ? 130.194 132.271 154.204 1.00 58.65  ? 397 GLN B CG  1 
ATOM   8048  C  CD  . GLN D 1 404 ? 129.571 131.445 153.100 1.00 58.65  ? 397 GLN B CD  1 
ATOM   8049  O  OE1 . GLN D 1 404 ? 128.456 130.946 153.237 1.00 58.65  ? 397 GLN B OE1 1 
ATOM   8050  N  NE2 . GLN D 1 404 ? 130.291 131.298 151.995 1.00 58.65  ? 397 GLN B NE2 1 
ATOM   8051  N  N   . THR D 1 405 ? 128.510 135.118 157.302 1.00 66.15  ? 398 THR B N   1 
ATOM   8052  C  CA  . THR D 1 405 ? 127.937 135.464 158.603 1.00 66.15  ? 398 THR B CA  1 
ATOM   8053  C  C   . THR D 1 405 ? 127.121 136.754 158.546 1.00 66.15  ? 398 THR B C   1 
ATOM   8054  O  O   . THR D 1 405 ? 127.321 137.681 159.330 1.00 66.15  ? 398 THR B O   1 
ATOM   8055  C  CB  . THR D 1 405 ? 129.047 135.561 159.644 1.00 66.15  ? 398 THR B CB  1 
ATOM   8056  O  OG1 . THR D 1 405 ? 128.522 136.117 160.857 1.00 66.15  ? 398 THR B OG1 1 
ATOM   8057  C  CG2 . THR D 1 405 ? 130.195 136.426 159.135 1.00 66.15  ? 398 THR B CG2 1 
ATOM   8058  N  N   . GLY D 1 406 ? 126.178 136.816 157.615 1.00 65.57  ? 399 GLY B N   1 
ATOM   8059  C  CA  . GLY D 1 406 ? 125.300 137.959 157.496 1.00 65.57  ? 399 GLY B CA  1 
ATOM   8060  C  C   . GLY D 1 406 ? 125.943 139.118 156.753 1.00 65.57  ? 399 GLY B C   1 
ATOM   8061  O  O   . GLY D 1 406 ? 127.146 139.151 156.497 1.00 65.57  ? 399 GLY B O   1 
ATOM   8062  N  N   . GLY D 1 407 ? 125.108 140.093 156.406 1.00 62.72  ? 400 GLY B N   1 
ATOM   8063  C  CA  . GLY D 1 407 ? 125.573 141.265 155.692 1.00 62.72  ? 400 GLY B CA  1 
ATOM   8064  C  C   . GLY D 1 407 ? 125.175 141.265 154.232 1.00 62.72  ? 400 GLY B C   1 
ATOM   8065  O  O   . GLY D 1 407 ? 125.871 141.840 153.390 1.00 62.72  ? 400 GLY B O   1 
ATOM   8066  N  N   . ILE D 1 408 ? 124.052 140.621 153.920 1.00 54.57  ? 401 ILE B N   1 
ATOM   8067  C  CA  . ILE D 1 408 ? 123.573 140.514 152.546 1.00 54.57  ? 401 ILE B CA  1 
ATOM   8068  C  C   . ILE D 1 408 ? 122.148 141.040 152.463 1.00 54.57  ? 401 ILE B C   1 
ATOM   8069  O  O   . ILE D 1 408 ? 121.575 141.480 153.466 1.00 54.57  ? 401 ILE B O   1 
ATOM   8070  C  CB  . ILE D 1 408 ? 123.652 139.062 152.044 1.00 54.57  ? 401 ILE B CB  1 
ATOM   8071  C  CG1 . ILE D 1 408 ? 122.741 138.167 152.884 1.00 54.57  ? 401 ILE B CG1 1 
ATOM   8072  C  CG2 . ILE D 1 408 ? 125.088 138.568 152.073 1.00 54.57  ? 401 ILE B CG2 1 
ATOM   8073  C  CD1 . ILE D 1 408 ? 123.082 136.699 152.806 1.00 54.57  ? 401 ILE B CD1 1 
ATOM   8074  N  N   . SER D 1 409 ? 121.568 140.997 151.265 1.00 50.69  ? 402 SER B N   1 
ATOM   8075  C  CA  . SER D 1 409 ? 120.204 141.449 151.039 1.00 50.69  ? 402 SER B CA  1 
ATOM   8076  C  C   . SER D 1 409 ? 119.505 140.448 150.130 1.00 50.69  ? 402 SER B C   1 
ATOM   8077  O  O   . SER D 1 409 ? 120.117 139.501 149.625 1.00 50.69  ? 402 SER B O   1 
ATOM   8078  C  CB  . SER D 1 409 ? 120.179 142.858 150.439 1.00 50.69  ? 402 SER B CB  1 
ATOM   8079  O  OG  . SER D 1 409 ? 121.286 143.062 149.579 1.00 50.69  ? 402 SER B OG  1 
ATOM   8080  N  N   . GLY D 1 410 ? 118.206 140.666 149.917 1.00 49.41  ? 403 GLY B N   1 
ATOM   8081  C  CA  . GLY D 1 410 ? 117.430 139.742 149.107 1.00 49.41  ? 403 GLY B CA  1 
ATOM   8082  C  C   . GLY D 1 410 ? 117.963 139.592 147.696 1.00 49.41  ? 403 GLY B C   1 
ATOM   8083  O  O   . GLY D 1 410 ? 117.815 138.532 147.083 1.00 49.41  ? 403 GLY B O   1 
ATOM   8084  N  N   . LEU D 1 411 ? 118.607 140.636 147.171 1.00 46.41  ? 404 LEU B N   1 
ATOM   8085  C  CA  . LEU D 1 411 ? 119.162 140.565 145.826 1.00 46.41  ? 404 LEU B CA  1 
ATOM   8086  C  C   . LEU D 1 411 ? 120.255 139.513 145.708 1.00 46.41  ? 404 LEU B C   1 
ATOM   8087  O  O   . LEU D 1 411 ? 120.607 139.127 144.589 1.00 46.41  ? 404 LEU B O   1 
ATOM   8088  C  CB  . LEU D 1 411 ? 119.708 141.930 145.406 1.00 46.41  ? 404 LEU B CB  1 
ATOM   8089  C  CG  . LEU D 1 411 ? 118.816 142.763 144.486 1.00 46.41  ? 404 LEU B CG  1 
ATOM   8090  C  CD1 . LEU D 1 411 ? 117.420 142.898 145.061 1.00 46.41  ? 404 LEU B CD1 1 
ATOM   8091  C  CD2 . LEU D 1 411 ? 119.431 144.126 144.253 1.00 46.41  ? 404 LEU B CD2 1 
ATOM   8092  N  N   . ASP D 1 412 ? 120.801 139.044 146.829 1.00 48.82  ? 405 ASP B N   1 
ATOM   8093  C  CA  . ASP D 1 412 ? 121.787 137.974 146.792 1.00 48.82  ? 405 ASP B CA  1 
ATOM   8094  C  C   . ASP D 1 412 ? 121.165 136.601 146.584 1.00 48.82  ? 405 ASP B C   1 
ATOM   8095  O  O   . ASP D 1 412 ? 121.894 135.656 146.268 1.00 48.82  ? 405 ASP B O   1 
ATOM   8096  C  CB  . ASP D 1 412 ? 122.610 137.976 148.079 1.00 48.82  ? 405 ASP B CB  1 
ATOM   8097  C  CG  . ASP D 1 412 ? 123.719 139.002 148.052 1.00 48.82  ? 405 ASP B CG  1 
ATOM   8098  O  OD1 . ASP D 1 412 ? 124.560 138.938 147.133 1.00 48.82  ? 405 ASP B OD1 1 
ATOM   8099  O  OD2 . ASP D 1 412 ? 123.746 139.875 148.944 1.00 48.82  ? 405 ASP B OD2 1 
ATOM   8100  N  N   . SER D 1 413 ? 119.840 136.499 146.734 1.00 47.21  ? 406 SER B N   1 
ATOM   8101  C  CA  . SER D 1 413 ? 119.168 135.212 146.417 1.00 47.21  ? 406 SER B CA  1 
ATOM   8102  C  C   . SER D 1 413 ? 119.408 134.924 144.933 1.00 47.21  ? 406 SER B C   1 
ATOM   8103  O  O   . SER D 1 413 ? 119.511 135.896 144.157 1.00 47.21  ? 406 SER B O   1 
ATOM   8104  C  CB  . SER D 1 413 ? 117.704 135.254 146.751 1.00 47.21  ? 406 SER B CB  1 
ATOM   8105  O  OG  . SER D 1 413 ? 117.511 135.554 148.125 1.00 47.21  ? 406 SER B OG  1 
ATOM   8106  N  N   . PHE D 1 414 ? 119.517 133.650 144.553 1.00 41.61  ? 407 PHE B N   1 
ATOM   8107  C  CA  . PHE D 1 414 ? 119.860 133.324 143.142 1.00 41.61  ? 407 PHE B CA  1 
ATOM   8108  C  C   . PHE D 1 414 ? 118.686 133.671 142.221 1.00 41.61  ? 407 PHE B C   1 
ATOM   8109  O  O   . PHE D 1 414 ? 118.687 133.214 141.062 1.00 41.61  ? 407 PHE B O   1 
ATOM   8110  C  CB  . PHE D 1 414 ? 120.345 131.876 143.041 1.00 41.61  ? 407 PHE B CB  1 
ATOM   8111  C  CG  . PHE D 1 414 ? 121.783 131.714 143.458 1.00 41.61  ? 407 PHE B CG  1 
ATOM   8112  C  CD1 . PHE D 1 414 ? 122.558 132.824 143.758 1.00 41.61  ? 407 PHE B CD1 1 
ATOM   8113  C  CD2 . PHE D 1 414 ? 122.360 130.462 143.570 1.00 41.61  ? 407 PHE B CD2 1 
ATOM   8114  C  CE1 . PHE D 1 414 ? 123.882 132.685 144.142 1.00 41.61  ? 407 PHE B CE1 1 
ATOM   8115  C  CE2 . PHE D 1 414 ? 123.683 130.325 143.958 1.00 41.61  ? 407 PHE B CE2 1 
ATOM   8116  C  CZ  . PHE D 1 414 ? 124.441 131.435 144.242 1.00 41.61  ? 407 PHE B CZ  1 
ATOM   8117  N  N   . GLY D 1 415 ? 117.723 134.455 142.716 1.00 45.85  ? 408 GLY B N   1 
ATOM   8118  C  CA  . GLY D 1 415 ? 116.631 134.919 141.840 1.00 45.85  ? 408 GLY B CA  1 
ATOM   8119  C  C   . GLY D 1 415 ? 117.197 135.831 140.767 1.00 45.85  ? 408 GLY B C   1 
ATOM   8120  O  O   . GLY D 1 415 ? 116.721 135.756 139.617 1.00 45.85  ? 408 GLY B O   1 
ATOM   8121  N  N   . ASN D 1 416 ? 118.177 136.665 141.130 1.00 41.69  ? 409 ASN B N   1 
ATOM   8122  C  CA  . ASN D 1 416 ? 118.856 137.539 140.138 1.00 41.69  ? 409 ASN B CA  1 
ATOM   8123  C  C   . ASN D 1 416 ? 120.067 136.790 139.575 1.00 41.69  ? 409 ASN B C   1 
ATOM   8124  O  O   . ASN D 1 416 ? 121.201 137.224 139.845 1.00 41.69  ? 409 ASN B O   1 
ATOM   8125  C  CB  . ASN D 1 416 ? 119.295 138.868 140.755 1.00 41.69  ? 409 ASN B CB  1 
ATOM   8126  C  CG  . ASN D 1 416 ? 118.152 139.841 140.949 1.00 41.69  ? 409 ASN B CG  1 
ATOM   8127  O  OD1 . ASN D 1 416 ? 117.029 139.573 140.533 1.00 41.69  ? 409 ASN B OD1 1 
ATOM   8128  N  ND2 . ASN D 1 416 ? 118.431 140.978 141.563 1.00 41.69  ? 409 ASN B ND2 1 
ATOM   8129  N  N   . LEU D 1 417 ? 119.832 135.699 138.839 1.00 36.69  ? 410 LEU B N   1 
ATOM   8130  C  CA  . LEU D 1 417 ? 120.946 134.900 138.262 1.00 36.69  ? 410 LEU B CA  1 
ATOM   8131  C  C   . LEU D 1 417 ? 120.403 134.023 137.132 1.00 36.69  ? 410 LEU B C   1 
ATOM   8132  O  O   . LEU D 1 417 ? 119.988 132.883 137.418 1.00 36.69  ? 410 LEU B O   1 
ATOM   8133  C  CB  . LEU D 1 417 ? 121.581 134.052 139.368 1.00 36.69  ? 410 LEU B CB  1 
ATOM   8134  C  CG  . LEU D 1 417 ? 122.910 133.392 139.001 1.00 36.69  ? 410 LEU B CG  1 
ATOM   8135  C  CD1 . LEU D 1 417 ? 123.940 134.441 138.613 1.00 36.69  ? 410 LEU B CD1 1 
ATOM   8136  C  CD2 . LEU D 1 417 ? 123.428 132.545 140.152 1.00 36.69  ? 410 LEU B CD2 1 
ATOM   8137  N  N   . GLU D 1 418 ? 120.404 134.541 135.900 1.00 36.36  ? 411 GLU B N   1 
ATOM   8138  C  CA  . GLU D 1 418 ? 119.902 133.785 134.764 1.00 36.36  ? 411 GLU B CA  1 
ATOM   8139  C  C   . GLU D 1 418 ? 120.911 133.872 133.631 1.00 36.36  ? 411 GLU B C   1 
ATOM   8140  O  O   . GLU D 1 418 ? 121.862 134.652 133.680 1.00 36.36  ? 411 GLU B O   1 
ATOM   8141  C  CB  . GLU D 1 418 ? 118.529 134.297 134.312 1.00 36.36  ? 411 GLU B CB  1 
ATOM   8142  C  CG  . GLU D 1 418 ? 117.451 134.143 135.367 1.00 36.36  ? 411 GLU B CG  1 
ATOM   8143  C  CD  . GLU D 1 418 ? 116.908 132.729 135.443 1.00 36.36  ? 411 GLU B CD  1 
ATOM   8144  O  OE1 . GLU D 1 418 ? 116.706 132.108 134.380 1.00 36.36  ? 411 GLU B OE1 1 
ATOM   8145  O  OE2 . GLU D 1 418 ? 116.688 132.238 136.570 1.00 36.36  ? 411 GLU B OE2 1 
ATOM   8146  N  N   . VAL D 1 419 ? 120.722 133.043 132.608 1.00 29.84  ? 412 VAL B N   1 
ATOM   8147  C  CA  . VAL D 1 419 ? 121.603 133.042 131.447 1.00 29.84  ? 412 VAL B CA  1 
ATOM   8148  C  C   . VAL D 1 419 ? 120.759 132.992 130.184 1.00 29.84  ? 412 VAL B C   1 
ATOM   8149  O  O   . VAL D 1 419 ? 119.793 132.228 130.098 1.00 29.84  ? 412 VAL B O   1 
ATOM   8150  C  CB  . VAL D 1 419 ? 122.595 131.864 131.472 1.00 29.84  ? 412 VAL B CB  1 
ATOM   8151  C  CG1 . VAL D 1 419 ? 123.577 131.982 130.328 1.00 29.84  ? 412 VAL B CG1 1 
ATOM   8152  C  CG2 . VAL D 1 419 ? 123.333 131.836 132.777 1.00 29.84  ? 412 VAL B CG2 1 
ATOM   8153  N  N   . SER D 1 420 ? 121.146 133.801 129.193 1.00 30.72  ? 413 SER B N   1 
ATOM   8154  C  CA  . SER D 1 420 ? 120.448 133.776 127.883 1.00 30.72  ? 413 SER B CA  1 
ATOM   8155  C  C   . SER D 1 420 ? 121.122 132.731 126.989 1.00 30.72  ? 413 SER B C   1 
ATOM   8156  O  O   . SER D 1 420 ? 122.300 132.416 127.241 1.00 30.72  ? 413 SER B O   1 
ATOM   8157  C  CB  . SER D 1 420 ? 120.479 135.136 127.242 1.00 30.72  ? 413 SER B CB  1 
ATOM   8158  O  OG  . SER D 1 420 ? 121.816 135.540 126.985 1.00 30.72  ? 413 SER B OG  1 
ATOM   8159  N  N   . PRO D 1 421 ? 120.440 132.174 125.964 1.00 33.44  ? 414 PRO B N   1 
ATOM   8160  C  CA  . PRO D 1 421 ? 121.071 131.231 125.034 1.00 33.44  ? 414 PRO B CA  1 
ATOM   8161  C  C   . PRO D 1 421 ? 122.127 131.940 124.170 1.00 33.44  ? 414 PRO B C   1 
ATOM   8162  O  O   . PRO D 1 421 ? 122.167 133.157 124.179 1.00 33.44  ? 414 PRO B O   1 
ATOM   8163  C  CB  . PRO D 1 421 ? 119.901 130.751 124.161 1.00 33.44  ? 414 PRO B CB  1 
ATOM   8164  C  CG  . PRO D 1 421 ? 118.670 131.078 124.976 1.00 33.44  ? 414 PRO B CG  1 
ATOM   8165  C  CD  . PRO D 1 421 ? 119.022 132.373 125.675 1.00 33.44  ? 414 PRO B CD  1 
ATOM   8166  N  N   . PRO D 1 422 ? 122.983 131.206 123.422 1.00 32.62  ? 415 PRO B N   1 
ATOM   8167  C  CA  . PRO D 1 422 ? 123.993 131.818 122.554 1.00 32.62  ? 415 PRO B CA  1 
ATOM   8168  C  C   . PRO D 1 422 ? 123.404 132.980 121.739 1.00 32.62  ? 415 PRO B C   1 
ATOM   8169  O  O   . PRO D 1 422 ? 122.342 132.806 121.169 1.00 32.62  ? 415 PRO B O   1 
ATOM   8170  C  CB  . PRO D 1 422 ? 124.429 130.682 121.614 1.00 32.62  ? 415 PRO B CB  1 
ATOM   8171  C  CG  . PRO D 1 422 ? 123.530 129.506 121.955 1.00 32.62  ? 415 PRO B CG  1 
ATOM   8172  C  CD  . PRO D 1 422 ? 123.053 129.747 123.371 1.00 32.62  ? 415 PRO B CD  1 
ATOM   8173  N  N   . VAL D 1 423 ? 124.104 134.122 121.694 1.00 34.75  ? 416 VAL B N   1 
ATOM   8174  C  CA  . VAL D 1 423 ? 123.541 135.323 121.003 1.00 34.75  ? 416 VAL B CA  1 
ATOM   8175  C  C   . VAL D 1 423 ? 124.601 136.001 120.129 1.00 34.75  ? 416 VAL B C   1 
ATOM   8176  O  O   . VAL D 1 423 ? 125.802 135.827 120.416 1.00 34.75  ? 416 VAL B O   1 
ATOM   8177  C  CB  . VAL D 1 423 ? 122.958 136.324 122.021 1.00 34.75  ? 416 VAL B CB  1 
ATOM   8178  C  CG1 . VAL D 1 423 ? 121.573 135.916 122.501 1.00 34.75  ? 416 VAL B CG1 1 
ATOM   8179  C  CG2 . VAL D 1 423 ? 123.896 136.546 123.198 1.00 34.75  ? 416 VAL B CG2 1 
ATOM   8180  N  N   . THR D 1 424 ? 124.167 136.742 119.104 1.00 41.09  ? 417 THR B N   1 
ATOM   8181  C  CA  . THR D 1 424 ? 125.074 137.492 118.238 1.00 41.09  ? 417 THR B CA  1 
ATOM   8182  C  C   . THR D 1 424 ? 124.633 138.949 118.272 1.00 41.09  ? 417 THR B C   1 
ATOM   8183  O  O   . THR D 1 424 ? 123.542 139.275 117.795 1.00 41.09  ? 417 THR B O   1 
ATOM   8184  C  CB  . THR D 1 424 ? 125.058 136.961 116.804 1.00 41.09  ? 417 THR B CB  1 
ATOM   8185  O  OG1 . THR D 1 424 ? 125.487 135.595 116.798 1.00 41.09  ? 417 THR B OG1 1 
ATOM   8186  C  CG2 . THR D 1 424 ? 125.980 137.775 115.916 1.00 41.09  ? 417 THR B CG2 1 
ATOM   8187  N  N   . VAL D 1 425 ? 125.469 139.821 118.828 1.00 44.54  ? 418 VAL B N   1 
ATOM   8188  C  CA  . VAL D 1 425 ? 125.156 141.240 118.949 1.00 44.54  ? 418 VAL B CA  1 
ATOM   8189  C  C   . VAL D 1 425 ? 126.137 142.034 118.095 1.00 44.54  ? 418 VAL B C   1 
ATOM   8190  O  O   . VAL D 1 425 ? 127.348 142.026 118.348 1.00 44.54  ? 418 VAL B O   1 
ATOM   8191  C  CB  . VAL D 1 425 ? 125.170 141.705 120.414 1.00 44.54  ? 418 VAL B CB  1 
ATOM   8192  C  CG1 . VAL D 1 425 ? 124.057 141.035 121.178 1.00 44.54  ? 418 VAL B CG1 1 
ATOM   8193  C  CG2 . VAL D 1 425 ? 126.492 141.384 121.085 1.00 44.54  ? 418 VAL B CG2 1 
ATOM   8194  N  N   . ARG D 1 426 ? 125.607 142.700 117.067 1.00 50.72  ? 419 ARG B N   1 
ATOM   8195  C  CA  . ARG D 1 426 ? 126.372 143.642 116.247 1.00 50.72  ? 419 ARG B CA  1 
ATOM   8196  C  C   . ARG D 1 426 ? 127.677 143.027 115.743 1.00 50.72  ? 419 ARG B C   1 
ATOM   8197  O  O   . ARG D 1 426 ? 128.732 143.664 115.748 1.00 50.72  ? 419 ARG B O   1 
ATOM   8198  C  CB  . ARG D 1 426 ? 126.635 144.935 117.019 1.00 50.72  ? 419 ARG B CB  1 
ATOM   8199  C  CG  . ARG D 1 426 ? 125.388 145.518 117.667 1.00 50.72  ? 419 ARG B CG  1 
ATOM   8200  C  CD  . ARG D 1 426 ? 125.719 146.664 118.608 1.00 50.72  ? 419 ARG B CD  1 
ATOM   8201  N  NE  . ARG D 1 426 ? 126.759 146.304 119.564 1.00 50.72  ? 419 ARG B NE  1 
ATOM   8202  C  CZ  . ARG D 1 426 ? 126.732 146.616 120.853 1.00 50.72  ? 419 ARG B CZ  1 
ATOM   8203  N  NH1 . ARG D 1 426 ? 125.724 147.293 121.378 1.00 50.72  ? 419 ARG B NH1 1 
ATOM   8204  N  NH2 . ARG D 1 426 ? 127.740 146.239 121.634 1.00 50.72  ? 419 ARG B NH2 1 
ATOM   8205  N  N   . GLY D 1 427 ? 127.604 141.769 115.309 1.00 50.66  ? 420 GLY B N   1 
ATOM   8206  C  CA  . GLY D 1 427 ? 128.744 141.089 114.734 1.00 50.66  ? 420 GLY B CA  1 
ATOM   8207  C  C   . GLY D 1 427 ? 129.619 140.330 115.710 1.00 50.66  ? 420 GLY B C   1 
ATOM   8208  O  O   . GLY D 1 427 ? 130.562 139.659 115.272 1.00 50.66  ? 420 GLY B O   1 
ATOM   8209  N  N   . LYS D 1 428 ? 129.347 140.411 117.010 1.00 44.71  ? 421 LYS B N   1 
ATOM   8210  C  CA  . LYS D 1 428 ? 130.127 139.702 118.016 1.00 44.71  ? 421 LYS B CA  1 
ATOM   8211  C  C   . LYS D 1 428 ? 129.315 138.533 118.558 1.00 44.71  ? 421 LYS B C   1 
ATOM   8212  O  O   . LYS D 1 428 ? 128.131 138.688 118.874 1.00 44.71  ? 421 LYS B O   1 
ATOM   8213  C  CB  . LYS D 1 428 ? 130.539 140.640 119.150 1.00 44.71  ? 421 LYS B CB  1 
ATOM   8214  C  CG  . LYS D 1 428 ? 131.563 140.038 120.095 1.00 44.71  ? 421 LYS B CG  1 
ATOM   8215  C  CD  . LYS D 1 428 ? 132.154 141.086 121.019 1.00 44.71  ? 421 LYS B CD  1 
ATOM   8216  C  CE  . LYS D 1 428 ? 133.129 140.460 122.001 1.00 44.71  ? 421 LYS B CE  1 
ATOM   8217  N  NZ  . LYS D 1 428 ? 134.177 139.660 121.308 1.00 44.71  ? 421 LYS B NZ  1 
ATOM   8218  N  N   . GLU D 1 429 ? 129.956 137.372 118.672 1.00 42.98  ? 422 GLU B N   1 
ATOM   8219  C  CA  . GLU D 1 429 ? 129.282 136.130 119.024 1.00 42.98  ? 422 GLU B CA  1 
ATOM   8220  C  C   . GLU D 1 429 ? 129.498 135.781 120.490 1.00 42.98  ? 422 GLU B C   1 
ATOM   8221  O  O   . GLU D 1 429 ? 130.602 135.933 121.020 1.00 42.98  ? 422 GLU B O   1 
ATOM   8222  C  CB  . GLU D 1 429 ? 129.787 134.977 118.155 1.00 42.98  ? 422 GLU B CB  1 
ATOM   8223  C  CG  . GLU D 1 429 ? 129.069 134.821 116.833 1.00 42.98  ? 422 GLU B CG  1 
ATOM   8224  C  CD  . GLU D 1 429 ? 129.210 133.425 116.263 1.00 42.98  ? 422 GLU B CD  1 
ATOM   8225  O  OE1 . GLU D 1 429 ? 130.002 132.633 116.816 1.00 42.98  ? 422 GLU B OE1 1 
ATOM   8226  O  OE2 . GLU D 1 429 ? 128.528 133.117 115.263 1.00 42.98  ? 422 GLU B OE2 1 
ATOM   8227  N  N   . TYR D 1 430 ? 128.436 135.309 121.141 1.00 37.19  ? 423 TYR B N   1 
ATOM   8228  C  CA  . TYR D 1 430 ? 128.519 134.697 122.466 1.00 37.19  ? 423 TYR B CA  1 
ATOM   8229  C  C   . TYR D 1 430 ? 127.862 133.327 122.402 1.00 37.19  ? 423 TYR B C   1 
ATOM   8230  O  O   . TYR D 1 430 ? 126.633 133.215 122.565 1.00 37.19  ? 423 TYR B O   1 
ATOM   8231  C  CB  . TYR D 1 430 ? 127.853 135.564 123.532 1.00 37.19  ? 423 TYR B CB  1 
ATOM   8232  C  CG  . TYR D 1 430 ? 128.418 136.961 123.638 1.00 37.19  ? 423 TYR B CG  1 
ATOM   8233  C  CD1 . TYR D 1 430 ? 127.943 137.987 122.839 1.00 37.19  ? 423 TYR B CD1 1 
ATOM   8234  C  CD2 . TYR D 1 430 ? 129.431 137.251 124.541 1.00 37.19  ? 423 TYR B CD2 1 
ATOM   8235  C  CE1 . TYR D 1 430 ? 128.457 139.259 122.937 1.00 37.19  ? 423 TYR B CE1 1 
ATOM   8236  C  CE2 . TYR D 1 430 ? 129.951 138.522 124.645 1.00 37.19  ? 423 TYR B CE2 1 
ATOM   8237  C  CZ  . TYR D 1 430 ? 129.459 139.522 123.840 1.00 37.19  ? 423 TYR B CZ  1 
ATOM   8238  O  OH  . TYR D 1 430 ? 129.973 140.793 123.935 1.00 37.19  ? 423 TYR B OH  1 
ATOM   8239  N  N   . PRO D 1 431 ? 128.624 132.264 122.127 1.00 34.35  ? 424 PRO B N   1 
ATOM   8240  C  CA  . PRO D 1 431 ? 128.033 130.918 122.082 1.00 34.35  ? 424 PRO B CA  1 
ATOM   8241  C  C   . PRO D 1 431 ? 127.678 130.347 123.442 1.00 34.35  ? 424 PRO B C   1 
ATOM   8242  O  O   . PRO D 1 431 ? 127.055 129.280 123.492 1.00 34.35  ? 424 PRO B O   1 
ATOM   8243  C  CB  . PRO D 1 431 ? 129.126 130.075 121.408 1.00 34.35  ? 424 PRO B CB  1 
ATOM   8244  C  CG  . PRO D 1 431 ? 130.038 131.060 120.755 1.00 34.35  ? 424 PRO B CG  1 
ATOM   8245  C  CD  . PRO D 1 431 ? 129.999 132.278 121.610 1.00 34.35  ? 424 PRO B CD  1 
ATOM   8246  N  N   . LEU D 1 432 ? 128.069 130.991 124.541 1.00 28.66  ? 425 LEU B N   1 
ATOM   8247  C  CA  . LEU D 1 432 ? 127.714 130.523 125.875 1.00 28.66  ? 425 LEU B CA  1 
ATOM   8248  C  C   . LEU D 1 432 ? 126.788 131.486 126.607 1.00 28.66  ? 425 LEU B C   1 
ATOM   8249  O  O   . LEU D 1 432 ? 126.599 131.347 127.819 1.00 28.66  ? 425 LEU B O   1 
ATOM   8250  C  CB  . LEU D 1 432 ? 128.972 130.267 126.707 1.00 28.66  ? 425 LEU B CB  1 
ATOM   8251  C  CG  . LEU D 1 432 ? 129.956 129.222 126.180 1.00 28.66  ? 425 LEU B CG  1 
ATOM   8252  C  CD1 . LEU D 1 432 ? 131.377 129.725 126.289 1.00 28.66  ? 425 LEU B CD1 1 
ATOM   8253  C  CD2 . LEU D 1 432 ? 129.804 127.914 126.925 1.00 28.66  ? 425 LEU B CD2 1 
ATOM   8254  N  N   . GLY D 1 433 ? 126.211 132.457 125.908 1.00 31.39  ? 426 GLY B N   1 
ATOM   8255  C  CA  . GLY D 1 433 ? 125.237 133.344 126.510 1.00 31.39  ? 426 GLY B CA  1 
ATOM   8256  C  C   . GLY D 1 433 ? 125.868 134.434 127.353 1.00 31.39  ? 426 GLY B C   1 
ATOM   8257  O  O   . GLY D 1 433 ? 127.085 134.604 127.414 1.00 31.39  ? 426 GLY B O   1 
ATOM   8258  N  N   . ARG D 1 434 ? 125.001 135.195 128.018 1.00 31.17  ? 427 ARG B N   1 
ATOM   8259  C  CA  . ARG D 1 434 ? 125.413 136.294 128.879 1.00 31.17  ? 427 ARG B CA  1 
ATOM   8260  C  C   . ARG D 1 434 ? 124.714 136.169 130.224 1.00 31.17  ? 427 ARG B C   1 
ATOM   8261  O  O   . ARG D 1 434 ? 123.508 135.911 130.276 1.00 31.17  ? 427 ARG B O   1 
ATOM   8262  C  CB  . ARG D 1 434 ? 125.084 137.646 128.244 1.00 31.17  ? 427 ARG B CB  1 
ATOM   8263  C  CG  . ARG D 1 434 ? 125.573 137.808 126.820 1.00 31.17  ? 427 ARG B CG  1 
ATOM   8264  C  CD  . ARG D 1 434 ? 125.644 139.274 126.430 1.00 31.17  ? 427 ARG B CD  1 
ATOM   8265  N  NE  . ARG D 1 434 ? 126.734 139.964 127.109 1.00 31.17  ? 427 ARG B NE  1 
ATOM   8266  C  CZ  . ARG D 1 434 ? 127.069 141.228 126.893 1.00 31.17  ? 427 ARG B CZ  1 
ATOM   8267  N  NH1 . ARG D 1 434 ? 126.407 141.981 126.032 1.00 31.17  ? 427 ARG B NH1 1 
ATOM   8268  N  NH2 . ARG D 1 434 ? 128.096 141.749 127.558 1.00 31.17  ? 427 ARG B NH2 1 
ATOM   8269  N  N   . ILE D 1 435 ? 125.471 136.353 131.307 1.00 30.15  ? 428 ILE B N   1 
ATOM   8270  C  CA  . ILE D 1 435 ? 124.886 136.340 132.642 1.00 30.15  ? 428 ILE B CA  1 
ATOM   8271  C  C   . ILE D 1 435 ? 123.977 137.548 132.809 1.00 30.15  ? 428 ILE B C   1 
ATOM   8272  O  O   . ILE D 1 435 ? 124.304 138.659 132.372 1.00 30.15  ? 428 ILE B O   1 
ATOM   8273  C  CB  . ILE D 1 435 ? 125.989 136.334 133.713 1.00 30.15  ? 428 ILE B CB  1 
ATOM   8274  C  CG1 . ILE D 1 435 ? 126.931 135.151 133.519 1.00 30.15  ? 428 ILE B CG1 1 
ATOM   8275  C  CG2 . ILE D 1 435 ? 125.383 136.267 135.094 1.00 30.15  ? 428 ILE B CG2 1 
ATOM   8276  C  CD1 . ILE D 1 435 ? 126.240 133.826 133.533 1.00 30.15  ? 428 ILE B CD1 1 
ATOM   8277  N  N   . LEU D 1 436 ? 122.828 137.341 133.446 1.00 32.13  ? 429 LEU B N   1 
ATOM   8278  C  CA  . LEU D 1 436 ? 121.871 138.405 133.718 1.00 32.13  ? 429 LEU B CA  1 
ATOM   8279  C  C   . LEU D 1 436 ? 121.569 138.416 135.208 1.00 32.13  ? 429 LEU B C   1 
ATOM   8280  O  O   . LEU D 1 436 ? 121.103 137.409 135.755 1.00 32.13  ? 429 LEU B O   1 
ATOM   8281  C  CB  . LEU D 1 436 ? 120.583 138.205 132.916 1.00 32.13  ? 429 LEU B CB  1 
ATOM   8282  C  CG  . LEU D 1 436 ? 120.697 138.061 131.400 1.00 32.13  ? 429 LEU B CG  1 
ATOM   8283  C  CD1 . LEU D 1 436 ? 119.321 137.934 130.781 1.00 32.13  ? 429 LEU B CD1 1 
ATOM   8284  C  CD2 . LEU D 1 436 ? 121.434 139.237 130.809 1.00 32.13  ? 429 LEU B CD2 1 
ATOM   8285  N  N   . PHE D 1 437 ? 121.838 139.546 135.857 1.00 35.34  ? 430 PHE B N   1 
ATOM   8286  C  CA  . PHE D 1 437 ? 121.445 139.758 137.241 1.00 35.34  ? 430 PHE B CA  1 
ATOM   8287  C  C   . PHE D 1 437 ? 120.958 141.188 137.400 1.00 35.34  ? 430 PHE B C   1 
ATOM   8288  O  O   . PHE D 1 437 ? 121.433 142.099 136.717 1.00 35.34  ? 430 PHE B O   1 
ATOM   8289  C  CB  . PHE D 1 437 ? 122.588 139.459 138.227 1.00 35.34  ? 430 PHE B CB  1 
ATOM   8290  C  CG  . PHE D 1 437 ? 123.805 140.316 138.052 1.00 35.34  ? 430 PHE B CG  1 
ATOM   8291  C  CD1 . PHE D 1 437 ? 123.895 141.550 138.668 1.00 35.34  ? 430 PHE B CD1 1 
ATOM   8292  C  CD2 . PHE D 1 437 ? 124.879 139.866 137.311 1.00 35.34  ? 430 PHE B CD2 1 
ATOM   8293  C  CE1 . PHE D 1 437 ? 125.022 142.328 138.520 1.00 35.34  ? 430 PHE B CE1 1 
ATOM   8294  C  CE2 . PHE D 1 437 ? 126.007 140.640 137.162 1.00 35.34  ? 430 PHE B CE2 1 
ATOM   8295  C  CZ  . PHE D 1 437 ? 126.078 141.873 137.765 1.00 35.34  ? 430 PHE B CZ  1 
ATOM   8296  N  N   . GLY D 1 438 ? 120.007 141.377 138.309 1.00 38.11  ? 431 GLY B N   1 
ATOM   8297  C  CA  . GLY D 1 438 ? 119.337 142.652 138.484 1.00 38.11  ? 431 GLY B CA  1 
ATOM   8298  C  C   . GLY D 1 438 ? 119.821 143.385 139.720 1.00 38.11  ? 431 GLY B C   1 
ATOM   8299  O  O   . GLY D 1 438 ? 120.260 142.767 140.692 1.00 38.11  ? 431 GLY B O   1 
ATOM   8300  N  N   . ASP D 1 439 ? 119.734 144.710 139.675 1.00 43.88  ? 432 ASP B N   1 
ATOM   8301  C  CA  . ASP D 1 439 ? 120.080 145.570 140.801 1.00 43.88  ? 432 ASP B CA  1 
ATOM   8302  C  C   . ASP D 1 439 ? 119.462 146.947 140.557 1.00 43.88  ? 432 ASP B C   1 
ATOM   8303  O  O   . ASP D 1 439 ? 118.762 147.161 139.562 1.00 43.88  ? 432 ASP B O   1 
ATOM   8304  C  CB  . ASP D 1 439 ? 121.601 145.554 141.041 1.00 43.88  ? 432 ASP B CB  1 
ATOM   8305  C  CG  . ASP D 1 439 ? 122.385 146.581 140.215 1.00 43.88  ? 432 ASP B CG  1 
ATOM   8306  O  OD1 . ASP D 1 439 ? 123.630 146.536 140.300 1.00 43.88  ? 432 ASP B OD1 1 
ATOM   8307  O  OD2 . ASP D 1 439 ? 121.821 147.385 139.448 1.00 43.88  ? 432 ASP B OD2 1 
ATOM   8308  N  N   . SER D 1 440 ? 119.725 147.883 141.466 1.00 47.00  ? 433 SER B N   1 
ATOM   8309  C  CA  . SER D 1 440 ? 119.063 149.179 141.432 1.00 47.00  ? 433 SER B CA  1 
ATOM   8310  C  C   . SER D 1 440 ? 119.547 150.019 140.251 1.00 47.00  ? 433 SER B C   1 
ATOM   8311  O  O   . SER D 1 440 ? 120.638 149.818 139.711 1.00 47.00  ? 433 SER B O   1 
ATOM   8312  C  CB  . SER D 1 440 ? 119.303 149.936 142.737 1.00 47.00  ? 433 SER B CB  1 
ATOM   8313  O  OG  . SER D 1 440 ? 120.677 150.232 142.909 1.00 47.00  ? 433 SER B OG  1 
ATOM   8314  N  N   . CYS D 1 441 ? 118.708 150.980 139.855 1.00 46.19  ? 434 CYS B N   1 
ATOM   8315  C  CA  . CYS D 1 441 ? 119.036 151.829 138.714 1.00 46.19  ? 434 CYS B CA  1 
ATOM   8316  C  C   . CYS D 1 441 ? 120.236 152.720 139.011 1.00 46.19  ? 434 CYS B C   1 
ATOM   8317  O  O   . CYS D 1 441 ? 121.188 152.777 138.225 1.00 46.19  ? 434 CYS B O   1 
ATOM   8318  C  CB  . CYS D 1 441 ? 117.825 152.675 138.325 1.00 46.19  ? 434 CYS B CB  1 
ATOM   8319  S  SG  . CYS D 1 441 ? 118.203 154.018 137.181 1.00 46.19  ? 434 CYS B SG  1 
ATOM   8320  N  N   . TYR D 1 442 ? 120.208 153.424 140.138 1.00 47.47  ? 435 TYR B N   1 
ATOM   8321  C  CA  . TYR D 1 442 ? 121.307 154.279 140.555 1.00 47.47  ? 435 TYR B CA  1 
ATOM   8322  C  C   . TYR D 1 442 ? 121.539 154.101 142.046 1.00 47.47  ? 435 TYR B C   1 
ATOM   8323  O  O   . TYR D 1 442 ? 120.587 153.865 142.799 1.00 47.47  ? 435 TYR B O   1 
ATOM   8324  C  CB  . TYR D 1 442 ? 121.030 155.758 140.237 1.00 47.47  ? 435 TYR B CB  1 
ATOM   8325  C  CG  . TYR D 1 442 ? 119.953 156.399 141.085 1.00 47.47  ? 435 TYR B CG  1 
ATOM   8326  C  CD1 . TYR D 1 442 ? 120.266 157.053 142.266 1.00 47.47  ? 435 TYR B CD1 1 
ATOM   8327  C  CD2 . TYR D 1 442 ? 118.623 156.357 140.697 1.00 47.47  ? 435 TYR B CD2 1 
ATOM   8328  C  CE1 . TYR D 1 442 ? 119.288 157.638 143.039 1.00 47.47  ? 435 TYR B CE1 1 
ATOM   8329  C  CE2 . TYR D 1 442 ? 117.638 156.941 141.464 1.00 47.47  ? 435 TYR B CE2 1 
ATOM   8330  C  CZ  . TYR D 1 442 ? 117.977 157.580 142.635 1.00 47.47  ? 435 TYR B CZ  1 
ATOM   8331  O  OH  . TYR D 1 442 ? 117.001 158.166 143.405 1.00 47.47  ? 435 TYR B OH  1 
ATOM   8332  N  N   . PRO D 1 443 ? 122.786 154.201 142.499 1.00 51.47  ? 436 PRO B N   1 
ATOM   8333  C  CA  . PRO D 1 443 ? 123.058 154.055 143.933 1.00 51.47  ? 436 PRO B CA  1 
ATOM   8334  C  C   . PRO D 1 443 ? 122.415 155.170 144.739 1.00 51.47  ? 436 PRO B C   1 
ATOM   8335  O  O   . PRO D 1 443 ? 122.431 156.337 144.343 1.00 51.47  ? 436 PRO B O   1 
ATOM   8336  C  CB  . PRO D 1 443 ? 124.586 154.118 144.011 1.00 51.47  ? 436 PRO B CB  1 
ATOM   8337  C  CG  . PRO D 1 443 ? 125.004 154.825 142.778 1.00 51.47  ? 436 PRO B CG  1 
ATOM   8338  C  CD  . PRO D 1 443 ? 124.012 154.451 141.725 1.00 51.47  ? 436 PRO B CD  1 
ATOM   8339  N  N   . SER D 1 444 ? 121.854 154.803 145.885 1.00 58.07  ? 437 SER B N   1 
ATOM   8340  C  CA  . SER D 1 444 ? 121.187 155.763 146.753 1.00 58.07  ? 437 SER B CA  1 
ATOM   8341  C  C   . SER D 1 444 ? 121.293 155.259 148.189 1.00 58.07  ? 437 SER B C   1 
ATOM   8342  O  O   . SER D 1 444 ? 122.137 154.414 148.504 1.00 58.07  ? 437 SER B O   1 
ATOM   8343  C  CB  . SER D 1 444 ? 119.733 155.986 146.303 1.00 58.07  ? 437 SER B CB  1 
ATOM   8344  O  OG  . SER D 1 444 ? 118.960 154.813 146.469 1.00 58.07  ? 437 SER B OG  1 
ATOM   8345  N  N   . ASN D 1 445 ? 120.444 155.790 149.066 1.00 65.89  ? 438 ASN B N   1 
ATOM   8346  C  CA  . ASN D 1 445 ? 120.459 155.425 150.477 1.00 65.89  ? 438 ASN B CA  1 
ATOM   8347  C  C   . ASN D 1 445 ? 119.545 154.252 150.829 1.00 65.89  ? 438 ASN B C   1 
ATOM   8348  O  O   . ASN D 1 445 ? 119.834 153.527 151.789 1.00 65.89  ? 438 ASN B O   1 
ATOM   8349  C  CB  . ASN D 1 445 ? 120.194 156.691 151.319 1.00 65.89  ? 438 ASN B CB  1 
ATOM   8350  C  CG  . ASN D 1 445 ? 118.711 156.959 151.623 1.00 65.89  ? 438 ASN B CG  1 
ATOM   8351  O  OD1 . ASN D 1 445 ? 117.818 156.173 151.322 1.00 65.89  ? 438 ASN B OD1 1 
ATOM   8352  N  ND2 . ASN D 1 445 ? 118.460 158.105 152.242 1.00 65.89  ? 438 ASN B ND2 1 
ATOM   8353  N  N   . ASP D 1 446 ? 118.451 154.046 150.098 1.00 65.92  ? 439 ASP B N   1 
ATOM   8354  C  CA  . ASP D 1 446 ? 117.601 152.871 150.273 1.00 65.92  ? 439 ASP B CA  1 
ATOM   8355  C  C   . ASP D 1 446 ? 117.699 151.879 149.120 1.00 65.92  ? 439 ASP B C   1 
ATOM   8356  O  O   . ASP D 1 446 ? 116.895 150.943 149.057 1.00 65.92  ? 439 ASP B O   1 
ATOM   8357  C  CB  . ASP D 1 446 ? 116.141 153.284 150.483 1.00 65.92  ? 439 ASP B CB  1 
ATOM   8358  C  CG  . ASP D 1 446 ? 115.856 153.731 151.905 1.00 65.92  ? 439 ASP B CG  1 
ATOM   8359  O  OD1 . ASP D 1 446 ? 114.699 153.572 152.350 1.00 65.92  ? 439 ASP B OD1 1 
ATOM   8360  O  OD2 . ASP D 1 446 ? 116.789 154.181 152.599 1.00 65.92  ? 439 ASP B OD2 1 
ATOM   8361  N  N   . SER D 1 447 ? 118.653 152.054 148.213 1.00 57.22  ? 440 SER B N   1 
ATOM   8362  C  CA  . SER D 1 447 ? 118.822 151.097 147.134 1.00 57.22  ? 440 SER B CA  1 
ATOM   8363  C  C   . SER D 1 447 ? 119.600 149.876 147.615 1.00 57.22  ? 440 SER B C   1 
ATOM   8364  O  O   . SER D 1 447 ? 120.372 149.935 148.576 1.00 57.22  ? 440 SER B O   1 
ATOM   8365  C  CB  . SER D 1 447 ? 119.544 151.734 145.949 1.00 57.22  ? 440 SER B CB  1 
ATOM   8366  O  OG  . SER D 1 447 ? 120.947 151.707 146.142 1.00 57.22  ? 440 SER B OG  1 
ATOM   8367  N  N   . ARG D 1 448 ? 119.389 148.759 146.926 1.00 52.52  ? 441 ARG B N   1 
ATOM   8368  C  CA  . ARG D 1 448 ? 120.093 147.516 147.194 1.00 52.52  ? 441 ARG B CA  1 
ATOM   8369  C  C   . ARG D 1 448 ? 120.926 147.133 145.980 1.00 52.52  ? 441 ARG B C   1 
ATOM   8370  O  O   . ARG D 1 448 ? 120.744 147.667 144.883 1.00 52.52  ? 441 ARG B O   1 
ATOM   8371  C  CB  . ARG D 1 448 ? 119.121 146.381 147.534 1.00 52.52  ? 441 ARG B CB  1 
ATOM   8372  C  CG  . ARG D 1 448 ? 118.273 146.629 148.762 1.00 52.52  ? 441 ARG B CG  1 
ATOM   8373  C  CD  . ARG D 1 448 ? 117.112 145.656 148.818 1.00 52.52  ? 441 ARG B CD  1 
ATOM   8374  N  NE  . ARG D 1 448 ? 116.173 145.867 147.725 1.00 52.52  ? 441 ARG B NE  1 
ATOM   8375  C  CZ  . ARG D 1 448 ? 115.141 145.077 147.464 1.00 52.52  ? 441 ARG B CZ  1 
ATOM   8376  N  NH1 . ARG D 1 448 ? 114.890 144.005 148.198 1.00 52.52  ? 441 ARG B NH1 1 
ATOM   8377  N  NH2 . ARG D 1 448 ? 114.340 145.371 146.445 1.00 52.52  ? 441 ARG B NH2 1 
ATOM   8378  N  N   . GLN D 1 449 ? 121.848 146.197 146.185 1.00 51.11  ? 442 GLN B N   1 
ATOM   8379  C  CA  . GLN D 1 449 ? 122.677 145.715 145.094 1.00 51.11  ? 442 GLN B CA  1 
ATOM   8380  C  C   . GLN D 1 449 ? 123.171 144.314 145.416 1.00 51.11  ? 442 GLN B C   1 
ATOM   8381  O  O   . GLN D 1 449 ? 123.262 143.917 146.580 1.00 51.11  ? 442 GLN B O   1 
ATOM   8382  C  CB  . GLN D 1 449 ? 123.861 146.652 144.832 1.00 51.11  ? 442 GLN B CB  1 
ATOM   8383  C  CG  . GLN D 1 449 ? 124.974 146.549 145.862 1.00 51.11  ? 442 GLN B CG  1 
ATOM   8384  C  CD  . GLN D 1 449 ? 126.301 147.066 145.342 1.00 51.11  ? 442 GLN B CD  1 
ATOM   8385  O  OE1 . GLN D 1 449 ? 126.442 147.369 144.158 1.00 51.11  ? 442 GLN B OE1 1 
ATOM   8386  N  NE2 . GLN D 1 449 ? 127.286 147.164 146.228 1.00 51.11  ? 442 GLN B NE2 1 
ATOM   8387  N  N   . MET D 1 450 ? 123.485 143.563 144.362 1.00 51.10  ? 443 MET B N   1 
ATOM   8388  C  CA  . MET D 1 450 ? 124.172 142.292 144.535 1.00 51.10  ? 443 MET B CA  1 
ATOM   8389  C  C   . MET D 1 450 ? 125.529 142.532 145.181 1.00 51.10  ? 443 MET B C   1 
ATOM   8390  O  O   . MET D 1 450 ? 126.165 143.567 144.972 1.00 51.10  ? 443 MET B O   1 
ATOM   8391  C  CB  . MET D 1 450 ? 124.349 141.586 143.191 1.00 51.10  ? 443 MET B CB  1 
ATOM   8392  C  CG  . MET D 1 450 ? 124.871 140.161 143.302 1.00 51.10  ? 443 MET B CG  1 
ATOM   8393  S  SD  . MET D 1 450 ? 124.482 139.122 141.883 1.00 51.10  ? 443 MET B SD  1 
ATOM   8394  C  CE  . MET D 1 450 ? 122.824 138.596 142.289 1.00 51.10  ? 443 MET B CE  1 
ATOM   8395  N  N   . HIS D 1 451 ? 125.967 141.569 145.987 1.00 49.02  ? 444 HIS B N   1 
ATOM   8396  C  CA  . HIS D 1 451 ? 127.220 141.738 146.707 1.00 49.02  ? 444 HIS B CA  1 
ATOM   8397  C  C   . HIS D 1 451 ? 128.386 141.897 145.740 1.00 49.02  ? 444 HIS B C   1 
ATOM   8398  O  O   . HIS D 1 451 ? 128.451 141.244 144.691 1.00 49.02  ? 444 HIS B O   1 
ATOM   8399  C  CB  . HIS D 1 451 ? 127.471 140.562 147.646 1.00 49.02  ? 444 HIS B CB  1 
ATOM   8400  C  CG  . HIS D 1 451 ? 128.450 140.871 148.733 1.00 49.02  ? 444 HIS B CG  1 
ATOM   8401  N  ND1 . HIS D 1 451 ? 129.811 140.722 148.571 1.00 49.02  ? 444 HIS B ND1 1 
ATOM   8402  C  CD2 . HIS D 1 451 ? 128.270 141.342 149.989 1.00 49.02  ? 444 HIS B CD2 1 
ATOM   8403  C  CE1 . HIS D 1 451 ? 130.426 141.077 149.685 1.00 49.02  ? 444 HIS B CE1 1 
ATOM   8404  N  NE2 . HIS D 1 451 ? 129.514 141.458 150.560 1.00 49.02  ? 444 HIS B NE2 1 
ATOM   8405  N  N   . GLN D 1 452 ? 129.313 142.781 146.109 1.00 46.53  ? 445 GLN B N   1 
ATOM   8406  C  CA  . GLN D 1 452 ? 130.425 143.096 145.226 1.00 46.53  ? 445 GLN B CA  1 
ATOM   8407  C  C   . GLN D 1 452 ? 131.300 141.881 144.969 1.00 46.53  ? 445 GLN B C   1 
ATOM   8408  O  O   . GLN D 1 452 ? 131.831 141.732 143.867 1.00 46.53  ? 445 GLN B O   1 
ATOM   8409  C  CB  . GLN D 1 452 ? 131.255 144.237 145.813 1.00 46.53  ? 445 GLN B CB  1 
ATOM   8410  C  CG  . GLN D 1 452 ? 132.019 145.028 144.770 1.00 46.53  ? 445 GLN B CG  1 
ATOM   8411  C  CD  . GLN D 1 452 ? 131.099 145.737 143.798 1.00 46.53  ? 445 GLN B CD  1 
ATOM   8412  O  OE1 . GLN D 1 452 ? 131.314 145.705 142.586 1.00 46.53  ? 445 GLN B OE1 1 
ATOM   8413  N  NE2 . GLN D 1 452 ? 130.060 146.372 144.324 1.00 46.53  ? 445 GLN B NE2 1 
ATOM   8414  N  N   . ALA D 1 453 ? 131.465 141.003 145.960 1.00 44.99  ? 446 ALA B N   1 
ATOM   8415  C  CA  . ALA D 1 453 ? 132.279 139.809 145.749 1.00 44.99  ? 446 ALA B CA  1 
ATOM   8416  C  C   . ALA D 1 453 ? 131.686 138.929 144.655 1.00 44.99  ? 446 ALA B C   1 
ATOM   8417  O  O   . ALA D 1 453 ? 132.401 138.464 143.758 1.00 44.99  ? 446 ALA B O   1 
ATOM   8418  C  CB  . ALA D 1 453 ? 132.420 139.032 147.056 1.00 44.99  ? 446 ALA B CB  1 
ATOM   8419  N  N   . LEU D 1 454 ? 130.370 138.706 144.703 1.00 42.27  ? 447 LEU B N   1 
ATOM   8420  C  CA  . LEU D 1 454 ? 129.715 137.921 143.663 1.00 42.27  ? 447 LEU B CA  1 
ATOM   8421  C  C   . LEU D 1 454 ? 129.805 138.611 142.309 1.00 42.27  ? 447 LEU B C   1 
ATOM   8422  O  O   . LEU D 1 454 ? 130.046 137.958 141.285 1.00 42.27  ? 447 LEU B O   1 
ATOM   8423  C  CB  . LEU D 1 454 ? 128.256 137.665 144.039 1.00 42.27  ? 447 LEU B CB  1 
ATOM   8424  C  CG  . LEU D 1 454 ? 128.019 136.971 145.380 1.00 42.27  ? 447 LEU B CG  1 
ATOM   8425  C  CD1 . LEU D 1 454 ? 126.548 136.639 145.569 1.00 42.27  ? 447 LEU B CD1 1 
ATOM   8426  C  CD2 . LEU D 1 454 ? 128.870 135.721 145.488 1.00 42.27  ? 447 LEU B CD2 1 
ATOM   8427  N  N   . GLN D 1 455 ? 129.614 139.934 142.281 1.00 40.86  ? 448 GLN B N   1 
ATOM   8428  C  CA  . GLN D 1 455 ? 129.686 140.648 141.007 1.00 40.86  ? 448 GLN B CA  1 
ATOM   8429  C  C   . GLN D 1 455 ? 131.079 140.556 140.395 1.00 40.86  ? 448 GLN B C   1 
ATOM   8430  O  O   . GLN D 1 455 ? 131.219 140.321 139.188 1.00 40.86  ? 448 GLN B O   1 
ATOM   8431  C  CB  . GLN D 1 455 ? 129.271 142.106 141.195 1.00 40.86  ? 448 GLN B CB  1 
ATOM   8432  C  CG  . GLN D 1 455 ? 127.835 142.385 140.788 1.00 40.86  ? 448 GLN B CG  1 
ATOM   8433  C  CD  . GLN D 1 455 ? 127.478 143.853 140.866 1.00 40.86  ? 448 GLN B CD  1 
ATOM   8434  O  OE1 . GLN D 1 455 ? 128.319 144.721 140.634 1.00 40.86  ? 448 GLN B OE1 1 
ATOM   8435  N  NE2 . GLN D 1 455 ? 126.224 144.140 141.192 1.00 40.86  ? 448 GLN B NE2 1 
ATOM   8436  N  N   . ASP D 1 456 ? 132.124 140.728 141.209 1.00 39.79  ? 449 ASP B N   1 
ATOM   8437  C  CA  . ASP D 1 456 ? 133.483 140.624 140.685 1.00 39.79  ? 449 ASP B CA  1 
ATOM   8438  C  C   . ASP D 1 456 ? 133.815 139.200 140.262 1.00 39.79  ? 449 ASP B C   1 
ATOM   8439  O  O   . ASP D 1 456 ? 134.525 139.003 139.273 1.00 39.79  ? 449 ASP B O   1 
ATOM   8440  C  CB  . ASP D 1 456 ? 134.513 141.131 141.698 1.00 39.79  ? 449 ASP B CB  1 
ATOM   8441  C  CG  . ASP D 1 456 ? 134.224 142.538 142.187 1.00 39.79  ? 449 ASP B CG  1 
ATOM   8442  O  OD1 . ASP D 1 456 ? 134.129 143.452 141.343 1.00 39.79  ? 449 ASP B OD1 1 
ATOM   8443  O  OD2 . ASP D 1 456 ? 134.167 142.747 143.416 1.00 39.79  ? 449 ASP B OD2 1 
ATOM   8444  N  N   . PHE D 1 457 ? 133.325 138.194 140.988 1.00 33.61  ? 450 PHE B N   1 
ATOM   8445  C  CA  . PHE D 1 457 ? 133.554 136.816 140.558 1.00 33.61  ? 450 PHE B CA  1 
ATOM   8446  C  C   . PHE D 1 457 ? 132.922 136.561 139.194 1.00 33.61  ? 450 PHE B C   1 
ATOM   8447  O  O   . PHE D 1 457 ? 133.565 136.018 138.284 1.00 33.61  ? 450 PHE B O   1 
ATOM   8448  C  CB  . PHE D 1 457 ? 133.004 135.842 141.599 1.00 33.61  ? 450 PHE B CB  1 
ATOM   8449  C  CG  . PHE D 1 457 ? 133.135 134.399 141.209 1.00 33.61  ? 450 PHE B CG  1 
ATOM   8450  C  CD1 . PHE D 1 457 ? 134.376 133.792 141.156 1.00 33.61  ? 450 PHE B CD1 1 
ATOM   8451  C  CD2 . PHE D 1 457 ? 132.019 133.647 140.897 1.00 33.61  ? 450 PHE B CD2 1 
ATOM   8452  C  CE1 . PHE D 1 457 ? 134.498 132.466 140.799 1.00 33.61  ? 450 PHE B CE1 1 
ATOM   8453  C  CE2 . PHE D 1 457 ? 132.139 132.321 140.539 1.00 33.61  ? 450 PHE B CE2 1 
ATOM   8454  C  CZ  . PHE D 1 457 ? 133.379 131.731 140.492 1.00 33.61  ? 450 PHE B CZ  1 
ATOM   8455  N  N   . LEU D 1 458 ? 131.664 136.977 139.027 1.00 35.22  ? 451 LEU B N   1 
ATOM   8456  C  CA  . LEU D 1 458 ? 130.983 136.777 137.753 1.00 35.22  ? 451 LEU B CA  1 
ATOM   8457  C  C   . LEU D 1 458 ? 131.687 137.520 136.627 1.00 35.22  ? 451 LEU B C   1 
ATOM   8458  O  O   . LEU D 1 458 ? 131.814 136.998 135.514 1.00 35.22  ? 451 LEU B O   1 
ATOM   8459  C  CB  . LEU D 1 458 ? 129.529 137.222 137.863 1.00 35.22  ? 451 LEU B CB  1 
ATOM   8460  C  CG  . LEU D 1 458 ? 128.666 136.390 138.807 1.00 35.22  ? 451 LEU B CG  1 
ATOM   8461  C  CD1 . LEU D 1 458 ? 127.234 136.875 138.765 1.00 35.22  ? 451 LEU B CD1 1 
ATOM   8462  C  CD2 . LEU D 1 458 ? 128.749 134.919 138.445 1.00 35.22  ? 451 LEU B CD2 1 
ATOM   8463  N  N   . SER D 1 459 ? 132.146 138.745 136.891 1.00 34.40  ? 452 SER B N   1 
ATOM   8464  C  CA  . SER D 1 459 ? 132.895 139.476 135.876 1.00 34.40  ? 452 SER B CA  1 
ATOM   8465  C  C   . SER D 1 459 ? 134.215 138.790 135.547 1.00 34.40  ? 452 SER B C   1 
ATOM   8466  O  O   . SER D 1 459 ? 134.617 138.755 134.380 1.00 34.40  ? 452 SER B O   1 
ATOM   8467  C  CB  . SER D 1 459 ? 133.140 140.912 136.334 1.00 34.40  ? 452 SER B CB  1 
ATOM   8468  O  OG  . SER D 1 459 ? 132.069 141.757 135.953 1.00 34.40  ? 452 SER B OG  1 
ATOM   8469  N  N   . ALA D 1 460 ? 134.901 138.243 136.555 1.00 31.96  ? 453 ALA B N   1 
ATOM   8470  C  CA  . ALA D 1 460 ? 136.169 137.563 136.317 1.00 31.96  ? 453 ALA B CA  1 
ATOM   8471  C  C   . ALA D 1 460 ? 135.985 136.316 135.467 1.00 31.96  ? 453 ALA B C   1 
ATOM   8472  O  O   . ALA D 1 460 ? 136.872 135.971 134.679 1.00 31.96  ? 453 ALA B O   1 
ATOM   8473  C  CB  . ALA D 1 460 ? 136.835 137.206 137.643 1.00 31.96  ? 453 ALA B CB  1 
ATOM   8474  N  N   . GLN D 1 461 ? 134.857 135.626 135.612 1.00 31.77  ? 454 GLN B N   1 
ATOM   8475  C  CA  . GLN D 1 461 ? 134.498 134.596 134.637 1.00 31.77  ? 454 GLN B CA  1 
ATOM   8476  C  C   . GLN D 1 461 ? 134.139 135.302 133.336 1.00 31.77  ? 454 GLN B C   1 
ATOM   8477  O  O   . GLN D 1 461 ? 133.022 135.795 133.170 1.00 31.77  ? 454 GLN B O   1 
ATOM   8478  C  CB  . GLN D 1 461 ? 133.341 133.744 135.143 1.00 31.77  ? 454 GLN B CB  1 
ATOM   8479  C  CG  . GLN D 1 461 ? 133.469 133.344 136.591 1.00 31.77  ? 454 GLN B CG  1 
ATOM   8480  C  CD  . GLN D 1 461 ? 134.709 132.524 136.850 1.00 31.77  ? 454 GLN B CD  1 
ATOM   8481  O  OE1 . GLN D 1 461 ? 134.828 131.396 136.378 1.00 31.77  ? 454 GLN B OE1 1 
ATOM   8482  N  NE2 . GLN D 1 461 ? 135.646 133.087 137.598 1.00 31.77  ? 454 GLN B NE2 1 
ATOM   8483  N  N   . GLN D 1 462 ? 135.092 135.358 132.404 1.00 30.04  ? 455 GLN B N   1 
ATOM   8484  C  CA  . GLN D 1 462 ? 134.913 136.199 131.223 1.00 30.04  ? 455 GLN B CA  1 
ATOM   8485  C  C   . GLN D 1 462 ? 133.898 135.606 130.255 1.00 30.04  ? 455 GLN B C   1 
ATOM   8486  O  O   . GLN D 1 462 ? 133.049 136.330 129.718 1.00 30.04  ? 455 GLN B O   1 
ATOM   8487  C  CB  . GLN D 1 462 ? 136.256 136.416 130.529 1.00 30.04  ? 455 GLN B CB  1 
ATOM   8488  C  CG  . GLN D 1 462 ? 137.426 136.564 131.487 1.00 30.04  ? 455 GLN B CG  1 
ATOM   8489  C  CD  . GLN D 1 462 ? 138.740 136.814 130.778 1.00 30.04  ? 455 GLN B CD  1 
ATOM   8490  O  OE1 . GLN D 1 462 ? 138.843 137.701 129.933 1.00 30.04  ? 455 GLN B OE1 1 
ATOM   8491  N  NE2 . GLN D 1 462 ? 139.757 136.033 131.123 1.00 30.04  ? 455 GLN B NE2 1 
ATOM   8492  N  N   . VAL D 1 463 ? 133.945 134.286 130.058 1.00 27.67  ? 456 VAL B N   1 
ATOM   8493  C  CA  . VAL D 1 463 ? 133.231 133.583 128.995 1.00 27.67  ? 456 VAL B CA  1 
ATOM   8494  C  C   . VAL D 1 463 ? 131.765 133.989 128.918 1.00 27.67  ? 456 VAL B C   1 
ATOM   8495  O  O   . VAL D 1 463 ? 131.135 133.881 127.861 1.00 27.67  ? 456 VAL B O   1 
ATOM   8496  C  CB  . VAL D 1 463 ? 133.358 132.061 129.175 1.00 27.67  ? 456 VAL B CB  1 
ATOM   8497  C  CG1 . VAL D 1 463 ? 134.782 131.622 128.904 1.00 27.67  ? 456 VAL B CG1 1 
ATOM   8498  C  CG2 . VAL D 1 463 ? 132.938 131.662 130.576 1.00 27.67  ? 456 VAL B CG2 1 
ATOM   8499  N  N   . GLN D 1 464 ? 131.205 134.461 130.026 1.00 29.10  ? 457 GLN B N   1 
ATOM   8500  C  CA  . GLN D 1 464 ? 129.860 135.028 130.029 1.00 29.10  ? 457 GLN B CA  1 
ATOM   8501  C  C   . GLN D 1 464 ? 129.955 136.388 130.713 1.00 29.10  ? 457 GLN B C   1 
ATOM   8502  O  O   . GLN D 1 464 ? 129.733 136.503 131.921 1.00 29.10  ? 457 GLN B O   1 
ATOM   8503  C  CB  . GLN D 1 464 ? 128.868 134.097 130.717 1.00 29.10  ? 457 GLN B CB  1 
ATOM   8504  C  CG  . GLN D 1 464 ? 128.883 132.680 130.174 1.00 29.10  ? 457 GLN B CG  1 
ATOM   8505  C  CD  . GLN D 1 464 ? 128.147 131.706 131.062 1.00 29.10  ? 457 GLN B CD  1 
ATOM   8506  O  OE1 . GLN D 1 464 ? 128.440 131.589 132.248 1.00 29.10  ? 457 GLN B OE1 1 
ATOM   8507  N  NE2 . GLN D 1 464 ? 127.189 130.992 130.488 1.00 29.10  ? 457 GLN B NE2 1 
ATOM   8508  N  N   . ALA D 1 465 ? 130.297 137.410 129.935 1.00 31.40  ? 458 ALA B N   1 
ATOM   8509  C  CA  . ALA D 1 465 ? 130.337 138.772 130.450 1.00 31.40  ? 458 ALA B CA  1 
ATOM   8510  C  C   . ALA D 1 465 ? 128.959 139.172 130.961 1.00 31.40  ? 458 ALA B C   1 
ATOM   8511  O  O   . ALA D 1 465 ? 127.984 139.120 130.197 1.00 31.40  ? 458 ALA B O   1 
ATOM   8512  C  CB  . ALA D 1 465 ? 130.798 139.739 129.363 1.00 31.40  ? 458 ALA B CB  1 
ATOM   8513  N  N   . PRO D 1 466 ? 128.830 139.578 132.220 1.00 32.20  ? 459 PRO B N   1 
ATOM   8514  C  CA  . PRO D 1 466 ? 127.501 139.803 132.795 1.00 32.20  ? 459 PRO B CA  1 
ATOM   8515  C  C   . PRO D 1 466 ? 126.841 141.066 132.265 1.00 32.20  ? 459 PRO B C   1 
ATOM   8516  O  O   . PRO D 1 466 ? 127.491 141.987 131.768 1.00 32.20  ? 459 PRO B O   1 
ATOM   8517  C  CB  . PRO D 1 466 ? 127.782 139.919 134.298 1.00 32.20  ? 459 PRO B CB  1 
ATOM   8518  C  CG  . PRO D 1 466 ? 129.148 139.332 134.489 1.00 32.20  ? 459 PRO B CG  1 
ATOM   8519  C  CD  . PRO D 1 466 ? 129.885 139.671 133.238 1.00 32.20  ? 459 PRO B CD  1 
ATOM   8520  N  N   . VAL D 1 467 ? 125.516 141.091 132.390 1.00 31.38  ? 460 VAL B N   1 
ATOM   8521  C  CA  . VAL D 1 467 ? 124.689 142.227 132.000 1.00 31.38  ? 460 VAL B CA  1 
ATOM   8522  C  C   . VAL D 1 467 ? 123.762 142.554 133.163 1.00 31.38  ? 460 VAL B C   1 
ATOM   8523  O  O   . VAL D 1 467 ? 123.094 141.662 133.695 1.00 31.38  ? 460 VAL B O   1 
ATOM   8524  C  CB  . VAL D 1 467 ? 123.876 141.927 130.727 1.00 31.38  ? 460 VAL B CB  1 
ATOM   8525  C  CG1 . VAL D 1 467 ? 122.807 142.979 130.514 1.00 31.38  ? 460 VAL B CG1 1 
ATOM   8526  C  CG2 . VAL D 1 467 ? 124.792 141.841 129.521 1.00 31.38  ? 460 VAL B CG2 1 
ATOM   8527  N  N   . LYS D 1 468 ? 123.720 143.824 133.551 1.00 35.46  ? 461 LYS B N   1 
ATOM   8528  C  CA  . LYS D 1 468 ? 122.920 144.273 134.683 1.00 35.46  ? 461 LYS B CA  1 
ATOM   8529  C  C   . LYS D 1 468 ? 121.539 144.713 134.216 1.00 35.46  ? 461 LYS B C   1 
ATOM   8530  O  O   . LYS D 1 468 ? 121.387 145.254 133.119 1.00 35.46  ? 461 LYS B O   1 
ATOM   8531  C  CB  . LYS D 1 468 ? 123.612 145.424 135.413 1.00 35.46  ? 461 LYS B CB  1 
ATOM   8532  C  CG  . LYS D 1 468 ? 124.754 144.983 136.312 1.00 35.46  ? 461 LYS B CG  1 
ATOM   8533  C  CD  . LYS D 1 468 ? 125.760 146.100 136.559 1.00 35.46  ? 461 LYS B CD  1 
ATOM   8534  C  CE  . LYS D 1 468 ? 125.085 147.453 136.708 1.00 35.46  ? 461 LYS B CE  1 
ATOM   8535  N  NZ  . LYS D 1 468 ? 124.158 147.490 137.870 1.00 35.46  ? 461 LYS B NZ  1 
ATOM   8536  N  N   . LEU D 1 469 ? 120.535 144.478 135.055 1.00 32.69  ? 462 LEU B N   1 
ATOM   8537  C  CA  . LEU D 1 469 ? 119.161 144.858 134.765 1.00 32.69  ? 462 LEU B CA  1 
ATOM   8538  C  C   . LEU D 1 469 ? 118.552 145.585 135.958 1.00 32.69  ? 462 LEU B C   1 
ATOM   8539  O  O   . LEU D 1 469 ? 119.085 145.569 137.070 1.00 32.69  ? 462 LEU B O   1 
ATOM   8540  C  CB  . LEU D 1 469 ? 118.309 143.637 134.402 1.00 32.69  ? 462 LEU B CB  1 
ATOM   8541  C  CG  . LEU D 1 469 ? 118.731 142.819 133.185 1.00 32.69  ? 462 LEU B CG  1 
ATOM   8542  C  CD1 . LEU D 1 469 ? 117.796 141.640 132.999 1.00 32.69  ? 462 LEU B CD1 1 
ATOM   8543  C  CD2 . LEU D 1 469 ? 118.745 143.690 131.949 1.00 32.69  ? 462 LEU B CD2 1 
ATOM   8544  N  N   . TYR D 1 470 ? 117.412 146.223 135.708 1.00 40.65  ? 463 TYR B N   1 
ATOM   8545  C  CA  . TYR D 1 470 ? 116.718 147.040 136.701 1.00 40.65  ? 463 TYR B CA  1 
ATOM   8546  C  C   . TYR D 1 470 ? 115.583 146.215 137.297 1.00 40.65  ? 463 TYR B C   1 
ATOM   8547  O  O   . TYR D 1 470 ? 114.467 146.208 136.774 1.00 40.65  ? 463 TYR B O   1 
ATOM   8548  C  CB  . TYR D 1 470 ? 116.202 148.325 136.062 1.00 40.65  ? 463 TYR B CB  1 
ATOM   8549  C  CG  . TYR D 1 470 ? 115.352 149.182 136.971 1.00 40.65  ? 463 TYR B CG  1 
ATOM   8550  C  CD1 . TYR D 1 470 ? 115.725 149.419 138.282 1.00 40.65  ? 463 TYR B CD1 1 
ATOM   8551  C  CD2 . TYR D 1 470 ? 114.177 149.756 136.511 1.00 40.65  ? 463 TYR B CD2 1 
ATOM   8552  C  CE1 . TYR D 1 470 ? 114.951 150.202 139.112 1.00 40.65  ? 463 TYR B CE1 1 
ATOM   8553  C  CE2 . TYR D 1 470 ? 113.396 150.539 137.333 1.00 40.65  ? 463 TYR B CE2 1 
ATOM   8554  C  CZ  . TYR D 1 470 ? 113.788 150.759 138.633 1.00 40.65  ? 463 TYR B CZ  1 
ATOM   8555  O  OH  . TYR D 1 470 ? 113.013 151.541 139.458 1.00 40.65  ? 463 TYR B OH  1 
ATOM   8556  N  N   . SER D 1 471 ? 115.871 145.520 138.400 1.00 43.69  ? 464 SER B N   1 
ATOM   8557  C  CA  . SER D 1 471 ? 114.872 144.704 139.080 1.00 43.69  ? 464 SER B CA  1 
ATOM   8558  C  C   . SER D 1 471 ? 114.804 145.004 140.572 1.00 43.69  ? 464 SER B C   1 
ATOM   8559  O  O   . SER D 1 471 ? 114.428 144.130 141.357 1.00 43.69  ? 464 SER B O   1 
ATOM   8560  C  CB  . SER D 1 471 ? 115.148 143.217 138.861 1.00 43.69  ? 464 SER B CB  1 
ATOM   8561  O  OG  . SER D 1 471 ? 116.382 142.842 139.445 1.00 43.69  ? 464 SER B OG  1 
ATOM   8562  N  N   . ASP D 1 472 ? 115.166 146.219 140.983 1.00 46.84  ? 465 ASP B N   1 
ATOM   8563  C  CA  . ASP D 1 472 ? 115.056 146.582 142.390 1.00 46.84  ? 465 ASP B CA  1 
ATOM   8564  C  C   . ASP D 1 472 ? 113.613 146.874 142.782 1.00 46.84  ? 465 ASP B C   1 
ATOM   8565  O  O   . ASP D 1 472 ? 113.253 146.748 143.958 1.00 46.84  ? 465 ASP B O   1 
ATOM   8566  C  CB  . ASP D 1 472 ? 115.946 147.786 142.690 1.00 46.84  ? 465 ASP B CB  1 
ATOM   8567  C  CG  . ASP D 1 472 ? 115.570 148.480 143.980 1.00 46.84  ? 465 ASP B CG  1 
ATOM   8568  O  OD1 . ASP D 1 472 ? 115.760 147.879 145.056 1.00 46.84  ? 465 ASP B OD1 1 
ATOM   8569  O  OD2 . ASP D 1 472 ? 115.075 149.624 143.919 1.00 46.84  ? 465 ASP B OD2 1 
ATOM   8570  N  N   . TRP D 1 473 ? 112.773 147.249 141.815 1.00 46.69  ? 466 TRP B N   1 
ATOM   8571  C  CA  . TRP D 1 473 ? 111.401 147.638 142.117 1.00 46.69  ? 466 TRP B CA  1 
ATOM   8572  C  C   . TRP D 1 473 ? 110.583 146.502 142.717 1.00 46.69  ? 466 TRP B C   1 
ATOM   8573  O  O   . TRP D 1 473 ? 109.632 146.769 143.460 1.00 46.69  ? 466 TRP B O   1 
ATOM   8574  C  CB  . TRP D 1 473 ? 110.717 148.165 140.855 1.00 46.69  ? 466 TRP B CB  1 
ATOM   8575  C  CG  . TRP D 1 473 ? 110.892 147.285 139.653 1.00 46.69  ? 466 TRP B CG  1 
ATOM   8576  C  CD1 . TRP D 1 473 ? 112.013 147.151 138.890 1.00 46.69  ? 466 TRP B CD1 1 
ATOM   8577  C  CD2 . TRP D 1 473 ? 109.908 146.425 139.070 1.00 46.69  ? 466 TRP B CD2 1 
ATOM   8578  N  NE1 . TRP D 1 473 ? 111.791 146.256 137.874 1.00 46.69  ? 466 TRP B NE1 1 
ATOM   8579  C  CE2 . TRP D 1 473 ? 110.504 145.797 137.962 1.00 46.69  ? 466 TRP B CE2 1 
ATOM   8580  C  CE3 . TRP D 1 473 ? 108.582 146.123 139.381 1.00 46.69  ? 466 TRP B CE3 1 
ATOM   8581  C  CZ2 . TRP D 1 473 ? 109.822 144.886 137.167 1.00 46.69  ? 466 TRP B CZ2 1 
ATOM   8582  C  CZ3 . TRP D 1 473 ? 107.906 145.220 138.591 1.00 46.69  ? 466 TRP B CZ3 1 
ATOM   8583  C  CH2 . TRP D 1 473 ? 108.526 144.611 137.496 1.00 46.69  ? 466 TRP B CH2 1 
ATOM   8584  N  N   . LEU D 1 474 ? 110.920 145.252 142.417 1.00 48.38  ? 467 LEU B N   1 
ATOM   8585  C  CA  . LEU D 1 474 ? 110.191 144.127 142.985 1.00 48.38  ? 467 LEU B CA  1 
ATOM   8586  C  C   . LEU D 1 474 ? 110.451 144.023 144.483 1.00 48.38  ? 467 LEU B C   1 
ATOM   8587  O  O   . LEU D 1 474 ? 111.548 144.313 144.967 1.00 48.38  ? 467 LEU B O   1 
ATOM   8588  C  CB  . LEU D 1 474 ? 110.589 142.827 142.294 1.00 48.38  ? 467 LEU B CB  1 
ATOM   8589  C  CG  . LEU D 1 474 ? 110.110 142.655 140.853 1.00 48.38  ? 467 LEU B CG  1 
ATOM   8590  C  CD1 . LEU D 1 474 ? 110.909 141.575 140.148 1.00 48.38  ? 467 LEU B CD1 1 
ATOM   8591  C  CD2 . LEU D 1 474 ? 108.631 142.328 140.826 1.00 48.38  ? 467 LEU B CD2 1 
ATOM   8592  N  N   . SER D 1 475 ? 109.419 143.604 145.223 1.00 52.74  ? 468 SER B N   1 
ATOM   8593  C  CA  . SER D 1 475 ? 109.544 143.497 146.674 1.00 52.74  ? 468 SER B CA  1 
ATOM   8594  C  C   . SER D 1 475 ? 110.639 142.515 147.060 1.00 52.74  ? 468 SER B C   1 
ATOM   8595  O  O   . SER D 1 475 ? 111.481 142.816 147.913 1.00 52.74  ? 468 SER B O   1 
ATOM   8596  C  CB  . SER D 1 475 ? 108.210 143.075 147.287 1.00 52.74  ? 468 SER B CB  1 
ATOM   8597  O  OG  . SER D 1 475 ? 108.312 142.969 148.696 1.00 52.74  ? 468 SER B OG  1 
ATOM   8598  N  N   . VAL D 1 476 ? 110.647 141.341 146.441 1.00 48.40  ? 469 VAL B N   1 
ATOM   8599  C  CA  . VAL D 1 476 ? 111.747 140.404 146.626 1.00 48.40  ? 469 VAL B CA  1 
ATOM   8600  C  C   . VAL D 1 476 ? 112.939 140.787 145.761 1.00 48.40  ? 469 VAL B C   1 
ATOM   8601  O  O   . VAL D 1 476 ? 114.089 140.677 146.191 1.00 48.40  ? 469 VAL B O   1 
ATOM   8602  C  CB  . VAL D 1 476 ? 111.261 138.970 146.338 1.00 48.40  ? 469 VAL B CB  1 
ATOM   8603  C  CG1 . VAL D 1 476 ? 110.456 138.925 145.049 1.00 48.40  ? 469 VAL B CG1 1 
ATOM   8604  C  CG2 . VAL D 1 476 ? 112.432 138.010 146.280 1.00 48.40  ? 469 VAL B CG2 1 
ATOM   8605  N  N   . GLY D 1 477 ? 112.685 141.264 144.543 1.00 49.08  ? 470 GLY B N   1 
ATOM   8606  C  CA  . GLY D 1 477 ? 113.746 141.711 143.665 1.00 49.08  ? 470 GLY B CA  1 
ATOM   8607  C  C   . GLY D 1 477 ? 114.438 140.581 142.937 1.00 49.08  ? 470 GLY B C   1 
ATOM   8608  O  O   . GLY D 1 477 ? 115.644 140.386 143.107 1.00 49.08  ? 470 GLY B O   1 
ATOM   8609  N  N   . HIS D 1 478 ? 113.692 139.821 142.136 1.00 47.27  ? 471 HIS B N   1 
ATOM   8610  C  CA  . HIS D 1 478 ? 114.226 138.674 141.413 1.00 47.27  ? 471 HIS B CA  1 
ATOM   8611  C  C   . HIS D 1 478 ? 113.917 138.808 139.928 1.00 47.27  ? 471 HIS B C   1 
ATOM   8612  O  O   . HIS D 1 478 ? 112.748 138.899 139.540 1.00 47.27  ? 471 HIS B O   1 
ATOM   8613  C  CB  . HIS D 1 478 ? 113.651 137.367 141.960 1.00 47.27  ? 471 HIS B CB  1 
ATOM   8614  C  CG  . HIS D 1 478 ? 114.236 136.953 143.273 1.00 47.27  ? 471 HIS B CG  1 
ATOM   8615  N  ND1 . HIS D 1 478 ? 113.887 135.782 143.906 1.00 47.27  ? 471 HIS B ND1 1 
ATOM   8616  C  CD2 . HIS D 1 478 ? 115.144 137.559 144.075 1.00 47.27  ? 471 HIS B CD2 1 
ATOM   8617  C  CE1 . HIS D 1 478 ? 114.556 135.680 145.041 1.00 47.27  ? 471 HIS B CE1 1 
ATOM   8618  N  NE2 . HIS D 1 478 ? 115.325 136.745 145.167 1.00 47.27  ? 471 HIS B NE2 1 
ATOM   8619  N  N   . VAL D 1 479 ? 114.964 138.784 139.099 1.00 43.27  ? 472 VAL B N   1 
ATOM   8620  C  CA  . VAL D 1 479 ? 114.790 138.835 137.655 1.00 43.27  ? 472 VAL B CA  1 
ATOM   8621  C  C   . VAL D 1 479 ? 114.065 137.615 137.121 1.00 43.27  ? 472 VAL B C   1 
ATOM   8622  O  O   . VAL D 1 479 ? 113.562 137.646 135.996 1.00 43.27  ? 472 VAL B O   1 
ATOM   8623  C  CB  . VAL D 1 479 ? 116.147 138.985 136.932 1.00 43.27  ? 472 VAL B CB  1 
ATOM   8624  C  CG1 . VAL D 1 479 ? 115.962 138.914 135.430 1.00 43.27  ? 472 VAL B CG1 1 
ATOM   8625  C  CG2 . VAL D 1 479 ? 116.817 140.277 137.333 1.00 43.27  ? 472 VAL B CG2 1 
ATOM   8626  N  N   . ASP D 1 480 ? 113.998 136.536 137.899 1.00 47.61  ? 473 ASP B N   1 
ATOM   8627  C  CA  . ASP D 1 480 ? 113.206 135.386 137.493 1.00 47.61  ? 473 ASP B CA  1 
ATOM   8628  C  C   . ASP D 1 480 ? 111.711 135.666 137.539 1.00 47.61  ? 473 ASP B C   1 
ATOM   8629  O  O   . ASP D 1 480 ? 110.930 134.842 137.052 1.00 47.61  ? 473 ASP B O   1 
ATOM   8630  C  CB  . ASP D 1 480 ? 113.587 134.165 138.354 1.00 47.61  ? 473 ASP B CB  1 
ATOM   8631  C  CG  . ASP D 1 480 ? 112.916 134.147 139.735 1.00 47.61  ? 473 ASP B CG  1 
ATOM   8632  O  OD1 . ASP D 1 480 ? 113.638 133.926 140.730 1.00 47.61  ? 473 ASP B OD1 1 
ATOM   8633  O  OD2 . ASP D 1 480 ? 111.680 134.280 139.848 1.00 47.61  ? 473 ASP B OD2 1 
ATOM   8634  N  N   . GLU D 1 481 ? 111.317 136.824 138.075 1.00 49.37  ? 474 GLU B N   1 
ATOM   8635  C  CA  . GLU D 1 481 ? 109.865 137.106 138.247 1.00 49.37  ? 474 GLU B CA  1 
ATOM   8636  C  C   . GLU D 1 481 ? 109.289 137.841 137.032 1.00 49.37  ? 474 GLU B C   1 
ATOM   8637  O  O   . GLU D 1 481 ? 108.069 138.089 137.035 1.00 49.37  ? 474 GLU B O   1 
ATOM   8638  C  CB  . GLU D 1 481 ? 109.633 137.933 139.511 1.00 49.37  ? 474 GLU B CB  1 
ATOM   8639  C  CG  . GLU D 1 481 ? 110.069 137.224 140.777 1.00 49.37  ? 474 GLU B CG  1 
ATOM   8640  C  CD  . GLU D 1 481 ? 109.204 137.541 141.984 1.00 49.37  ? 474 GLU B CD  1 
ATOM   8641  O  OE1 . GLU D 1 481 ? 108.726 138.689 142.078 1.00 49.37  ? 474 GLU B OE1 1 
ATOM   8642  O  OE2 . GLU D 1 481 ? 109.010 136.640 142.822 1.00 49.37  ? 474 GLU B OE2 1 
ATOM   8643  N  N   . PHE D 1 482 ? 110.115 138.191 136.040 1.00 40.19  ? 475 PHE B N   1 
ATOM   8644  C  CA  . PHE D 1 482 ? 109.571 138.994 134.911 1.00 40.19  ? 475 PHE B CA  1 
ATOM   8645  C  C   . PHE D 1 482 ? 110.201 138.579 133.576 1.00 40.19  ? 475 PHE B C   1 
ATOM   8646  O  O   . PHE D 1 482 ? 109.699 139.033 132.530 1.00 40.19  ? 475 PHE B O   1 
ATOM   8647  C  CB  . PHE D 1 482 ? 109.731 140.493 135.188 1.00 40.19  ? 475 PHE B CB  1 
ATOM   8648  C  CG  . PHE D 1 482 ? 111.144 140.985 135.377 1.00 40.19  ? 475 PHE B CG  1 
ATOM   8649  C  CD1 . PHE D 1 482 ? 112.061 140.954 134.339 1.00 40.19  ? 475 PHE B CD1 1 
ATOM   8650  C  CD2 . PHE D 1 482 ? 111.555 141.491 136.599 1.00 40.19  ? 475 PHE B CD2 1 
ATOM   8651  C  CE1 . PHE D 1 482 ? 113.356 141.413 134.518 1.00 40.19  ? 475 PHE B CE1 1 
ATOM   8652  C  CE2 . PHE D 1 482 ? 112.850 141.950 136.778 1.00 40.19  ? 475 PHE B CE2 1 
ATOM   8653  C  CZ  . PHE D 1 482 ? 113.748 141.910 135.738 1.00 40.19  ? 475 PHE B CZ  1 
ATOM   8654  N  N   . LEU D 1 483 ? 111.263 137.767 133.585 1.00 40.17  ? 476 LEU B N   1 
ATOM   8655  C  CA  . LEU D 1 483 ? 111.784 137.276 132.275 1.00 40.17  ? 476 LEU B CA  1 
ATOM   8656  C  C   . LEU D 1 483 ? 111.927 135.749 132.295 1.00 40.17  ? 476 LEU B C   1 
ATOM   8657  O  O   . LEU D 1 483 ? 112.068 135.185 133.396 1.00 40.17  ? 476 LEU B O   1 
ATOM   8658  C  CB  . LEU D 1 483 ? 113.082 137.994 131.871 1.00 40.17  ? 476 LEU B CB  1 
ATOM   8659  C  CG  . LEU D 1 483 ? 114.399 137.598 132.537 1.00 40.17  ? 476 LEU B CG  1 
ATOM   8660  C  CD1 . LEU D 1 483 ? 114.917 136.266 132.015 1.00 40.17  ? 476 LEU B CD1 1 
ATOM   8661  C  CD2 . LEU D 1 483 ? 115.439 138.672 132.259 1.00 40.17  ? 476 LEU B CD2 1 
ATOM   8662  N  N   . SER D 1 484 ? 111.879 135.122 131.117 1.00 39.08  ? 477 SER B N   1 
ATOM   8663  C  CA  . SER D 1 484 ? 111.986 133.642 130.996 1.00 39.08  ? 477 SER B CA  1 
ATOM   8664  C  C   . SER D 1 484 ? 112.387 133.272 129.563 1.00 39.08  ? 477 SER B C   1 
ATOM   8665  O  O   . SER D 1 484 ? 111.958 133.981 128.631 1.00 39.08  ? 477 SER B O   1 
ATOM   8666  C  CB  . SER D 1 484 ? 110.700 132.965 131.390 1.00 39.08  ? 477 SER B CB  1 
ATOM   8667  O  OG  . SER D 1 484 ? 110.499 133.040 132.793 1.00 39.08  ? 477 SER B OG  1 
ATOM   8668  N  N   . PHE D 1 485 ? 113.173 132.203 129.396 1.00 35.70  ? 478 PHE B N   1 
ATOM   8669  C  CA  . PHE D 1 485 ? 113.585 131.778 128.068 1.00 35.70  ? 478 PHE B CA  1 
ATOM   8670  C  C   . PHE D 1 485 ? 112.950 130.438 127.725 1.00 35.70  ? 478 PHE B C   1 
ATOM   8671  O  O   . PHE D 1 485 ? 112.741 129.588 128.596 1.00 35.70  ? 478 PHE B O   1 
ATOM   8672  C  CB  . PHE D 1 485 ? 115.106 131.674 127.960 1.00 35.70  ? 478 PHE B CB  1 
ATOM   8673  C  CG  . PHE D 1 485 ? 115.804 132.996 128.010 1.00 35.70  ? 478 PHE B CG  1 
ATOM   8674  C  CD1 . PHE D 1 485 ? 116.202 133.539 129.214 1.00 35.70  ? 478 PHE B CD1 1 
ATOM   8675  C  CD2 . PHE D 1 485 ? 116.049 133.704 126.849 1.00 35.70  ? 478 PHE B CD2 1 
ATOM   8676  C  CE1 . PHE D 1 485 ? 116.845 134.759 129.258 1.00 35.70  ? 478 PHE B CE1 1 
ATOM   8677  C  CE2 . PHE D 1 485 ? 116.690 134.925 126.887 1.00 35.70  ? 478 PHE B CE2 1 
ATOM   8678  C  CZ  . PHE D 1 485 ? 117.088 135.454 128.092 1.00 35.70  ? 478 PHE B CZ  1 
ATOM   8679  N  N   . VAL D 1 486 ? 112.566 130.286 126.457 1.00 41.24  ? 479 VAL B N   1 
ATOM   8680  C  CA  . VAL D 1 486 ? 111.899 129.031 126.006 1.00 41.24  ? 479 VAL B CA  1 
ATOM   8681  C  C   . VAL D 1 486 ? 112.580 128.586 124.709 1.00 41.24  ? 479 VAL B C   1 
ATOM   8682  O  O   . VAL D 1 486 ? 112.861 129.460 123.864 1.00 41.24  ? 479 VAL B O   1 
ATOM   8683  C  CB  . VAL D 1 486 ? 110.385 129.247 125.816 1.00 41.24  ? 479 VAL B CB  1 
ATOM   8684  C  CG1 . VAL D 1 486 ? 109.675 129.590 127.117 1.00 41.24  ? 479 VAL B CG1 1 
ATOM   8685  C  CG2 . VAL D 1 486 ? 110.088 130.288 124.746 1.00 41.24  ? 479 VAL B CG2 1 
ATOM   8686  N  N   . PRO D 1 487 ? 112.858 127.280 124.509 1.00 42.63  ? 480 PRO B N   1 
ATOM   8687  C  CA  . PRO D 1 487 ? 113.459 126.812 123.255 1.00 42.63  ? 480 PRO B CA  1 
ATOM   8688  C  C   . PRO D 1 487 ? 112.461 126.858 122.108 1.00 42.63  ? 480 PRO B C   1 
ATOM   8689  O  O   . PRO D 1 487 ? 111.289 126.504 122.259 1.00 42.63  ? 480 PRO B O   1 
ATOM   8690  C  CB  . PRO D 1 487 ? 113.871 125.372 123.576 1.00 42.63  ? 480 PRO B CB  1 
ATOM   8691  C  CG  . PRO D 1 487 ? 112.931 124.945 124.637 1.00 42.63  ? 480 PRO B CG  1 
ATOM   8692  C  CD  . PRO D 1 487 ? 112.561 126.170 125.430 1.00 42.63  ? 480 PRO B CD  1 
ATOM   8693  N  N   . ALA D 1 488 ? 112.942 127.301 120.948 1.00 44.89  ? 481 ALA B N   1 
ATOM   8694  C  CA  . ALA D 1 488 ? 112.098 127.483 119.780 1.00 44.89  ? 481 ALA B CA  1 
ATOM   8695  C  C   . ALA D 1 488 ? 112.719 126.811 118.564 1.00 44.89  ? 481 ALA B C   1 
ATOM   8696  O  O   . ALA D 1 488 ? 113.929 126.929 118.337 1.00 44.89  ? 481 ALA B O   1 
ATOM   8697  C  CB  . ALA D 1 488 ? 111.879 128.973 119.492 1.00 44.89  ? 481 ALA B CB  1 
ATOM   8698  N  N   . PRO D 1 489 ? 111.923 126.081 117.779 1.00 50.44  ? 482 PRO B N   1 
ATOM   8699  C  CA  . PRO D 1 489 ? 112.478 125.442 116.572 1.00 50.44  ? 482 PRO B CA  1 
ATOM   8700  C  C   . PRO D 1 489 ? 113.069 126.417 115.567 1.00 50.44  ? 482 PRO B C   1 
ATOM   8701  O  O   . PRO D 1 489 ? 114.090 126.105 114.943 1.00 50.44  ? 482 PRO B O   1 
ATOM   8702  C  CB  . PRO D 1 489 ? 111.271 124.704 115.976 1.00 50.44  ? 482 PRO B CB  1 
ATOM   8703  C  CG  . PRO D 1 489 ? 110.265 124.597 117.063 1.00 50.44  ? 482 PRO B CG  1 
ATOM   8704  C  CD  . PRO D 1 489 ? 110.645 125.488 118.203 1.00 50.44  ? 482 PRO B CD  1 
ATOM   8705  N  N   . ASP D 1 490 ? 112.466 127.587 115.393 1.00 50.58  ? 483 ASP B N   1 
ATOM   8706  C  CA  . ASP D 1 490 ? 112.771 128.471 114.273 1.00 50.58  ? 483 ASP B CA  1 
ATOM   8707  C  C   . ASP D 1 490 ? 113.469 129.740 114.754 1.00 50.58  ? 483 ASP B C   1 
ATOM   8708  O  O   . ASP D 1 490 ? 113.643 129.970 115.952 1.00 50.58  ? 483 ASP B O   1 
ATOM   8709  C  CB  . ASP D 1 490 ? 111.494 128.816 113.503 1.00 50.58  ? 483 ASP B CB  1 
ATOM   8710  C  CG  . ASP D 1 490 ? 110.411 129.383 114.400 1.00 50.58  ? 483 ASP B CG  1 
ATOM   8711  O  OD1 . ASP D 1 490 ? 110.016 128.692 115.361 1.00 50.58  ? 483 ASP B OD1 1 
ATOM   8712  O  OD2 . ASP D 1 490 ? 109.955 130.516 114.142 1.00 50.58  ? 483 ASP B OD2 1 
ATOM   8713  N  N   . ARG D 1 491 ? 113.870 130.562 113.785 1.00 47.81  ? 484 ARG B N   1 
ATOM   8714  C  CA  . ARG D 1 491 ? 114.517 131.864 114.011 1.00 47.81  ? 484 ARG B CA  1 
ATOM   8715  C  C   . ARG D 1 491 ? 115.814 131.619 114.781 1.00 47.81  ? 484 ARG B C   1 
ATOM   8716  O  O   . ARG D 1 491 ? 116.549 130.677 114.444 1.00 47.81  ? 484 ARG B O   1 
ATOM   8717  C  CB  . ARG D 1 491 ? 113.528 132.815 114.673 1.00 47.81  ? 484 ARG B CB  1 
ATOM   8718  C  CG  . ARG D 1 491 ? 112.343 133.189 113.797 1.00 47.81  ? 484 ARG B CG  1 
ATOM   8719  C  CD  . ARG D 1 491 ? 111.437 134.196 114.493 1.00 47.81  ? 484 ARG B CD  1 
ATOM   8720  N  NE  . ARG D 1 491 ? 110.278 134.557 113.684 1.00 47.81  ? 484 ARG B NE  1 
ATOM   8721  C  CZ  . ARG D 1 491 ? 110.279 135.474 112.726 1.00 47.81  ? 484 ARG B CZ  1 
ATOM   8722  N  NH1 . ARG D 1 491 ? 111.366 136.171 112.436 1.00 47.81  ? 484 ARG B NH1 1 
ATOM   8723  N  NH2 . ARG D 1 491 ? 109.160 135.703 112.047 1.00 47.81  ? 484 ARG B NH2 1 
ATOM   8724  N  N   . LYS D 1 492 ? 116.134 132.414 115.803 1.00 41.83  ? 485 LYS B N   1 
ATOM   8725  C  CA  . LYS D 1 492 ? 117.395 132.265 116.516 1.00 41.83  ? 485 LYS B CA  1 
ATOM   8726  C  C   . LYS D 1 492 ? 117.464 130.988 117.341 1.00 41.83  ? 485 LYS B C   1 
ATOM   8727  O  O   . LYS D 1 492 ? 118.542 130.656 117.843 1.00 41.83  ? 485 LYS B O   1 
ATOM   8728  C  CB  . LYS D 1 492 ? 117.631 133.472 117.425 1.00 41.83  ? 485 LYS B CB  1 
ATOM   8729  C  CG  . LYS D 1 492 ? 117.723 134.793 116.688 1.00 41.83  ? 485 LYS B CG  1 
ATOM   8730  C  CD  . LYS D 1 492 ? 118.923 134.823 115.761 1.00 41.83  ? 485 LYS B CD  1 
ATOM   8731  C  CE  . LYS D 1 492 ? 119.055 136.173 115.080 1.00 41.83  ? 485 LYS B CE  1 
ATOM   8732  N  NZ  . LYS D 1 492 ? 120.213 136.206 114.152 1.00 41.83  ? 485 LYS B NZ  1 
ATOM   8733  N  N   . GLY D 1 493 ? 116.319 130.344 117.563 1.00 41.33  ? 486 GLY B N   1 
ATOM   8734  C  CA  . GLY D 1 493 ? 116.305 129.136 118.408 1.00 41.33  ? 486 GLY B CA  1 
ATOM   8735  C  C   . GLY D 1 493 ? 115.673 129.381 119.763 1.00 41.33  ? 486 GLY B C   1 
ATOM   8736  O  O   . GLY D 1 493 ? 115.286 128.390 120.407 1.00 41.33  ? 486 GLY B O   1 
ATOM   8737  N  N   . PHE D 1 494 ? 115.581 130.640 120.199 1.00 36.83  ? 487 PHE B N   1 
ATOM   8738  C  CA  . PHE D 1 494 ? 115.025 130.947 121.546 1.00 36.83  ? 487 PHE B CA  1 
ATOM   8739  C  C   . PHE D 1 494 ? 113.908 131.971 121.403 1.00 36.83  ? 487 PHE B C   1 
ATOM   8740  O  O   . PHE D 1 494 ? 113.654 132.409 120.267 1.00 36.83  ? 487 PHE B O   1 
ATOM   8741  C  CB  . PHE D 1 494 ? 116.115 131.395 122.523 1.00 36.83  ? 487 PHE B CB  1 
ATOM   8742  C  CG  . PHE D 1 494 ? 116.838 132.699 122.226 1.00 36.83  ? 487 PHE B CG  1 
ATOM   8743  C  CD1 . PHE D 1 494 ? 118.036 132.702 121.525 1.00 36.83  ? 487 PHE B CD1 1 
ATOM   8744  C  CD2 . PHE D 1 494 ? 116.337 133.910 122.683 1.00 36.83  ? 487 PHE B CD2 1 
ATOM   8745  C  CE1 . PHE D 1 494 ? 118.700 133.889 121.268 1.00 36.83  ? 487 PHE B CE1 1 
ATOM   8746  C  CE2 . PHE D 1 494 ? 117.005 135.092 122.422 1.00 36.83  ? 487 PHE B CE2 1 
ATOM   8747  C  CZ  . PHE D 1 494 ? 118.182 135.080 121.715 1.00 36.83  ? 487 PHE B CZ  1 
ATOM   8748  N  N   . ARG D 1 495 ? 113.231 132.286 122.509 1.00 30.00  ? 488 ARG B N   1 
ATOM   8749  C  CA  . ARG D 1 495 ? 112.150 133.303 122.511 1.00 30.00  ? 488 ARG B CA  1 
ATOM   8750  C  C   . ARG D 1 495 ? 112.050 133.821 123.951 1.00 30.00  ? 488 ARG B C   1 
ATOM   8751  O  O   . ARG D 1 495 ? 111.599 133.054 124.824 1.00 30.00  ? 488 ARG B O   1 
ATOM   8752  C  CB  . ARG D 1 495 ? 110.819 132.719 122.034 1.00 30.00  ? 488 ARG B CB  1 
ATOM   8753  C  CG  . ARG D 1 495 ? 110.817 132.291 120.575 1.00 30.00  ? 488 ARG B CG  1 
ATOM   8754  C  CD  . ARG D 1 495 ? 109.475 131.777 120.080 1.00 30.00  ? 488 ARG B CD  1 
ATOM   8755  N  NE  . ARG D 1 495 ? 109.530 131.358 118.683 1.00 30.00  ? 488 ARG B NE  1 
ATOM   8756  C  CZ  . ARG D 1 495 ? 109.417 132.183 117.652 1.00 30.00  ? 488 ARG B CZ  1 
ATOM   8757  N  NH1 . ARG D 1 495 ? 109.246 133.484 117.856 1.00 30.00  ? 488 ARG B NH1 1 
ATOM   8758  N  NH2 . ARG D 1 495 ? 109.479 131.714 116.413 1.00 30.00  ? 488 ARG B NH2 1 
ATOM   8759  N  N   . LEU D 1 496 ? 112.493 135.055 124.193 1.00 39.20  ? 489 LEU B N   1 
ATOM   8760  C  CA  . LEU D 1 496 ? 112.388 135.614 125.566 1.00 39.20  ? 489 LEU B CA  1 
ATOM   8761  C  C   . LEU D 1 496 ? 110.922 135.946 125.892 1.00 39.20  ? 489 LEU B C   1 
ATOM   8762  O  O   . LEU D 1 496 ? 110.264 136.563 125.036 1.00 39.20  ? 489 LEU B O   1 
ATOM   8763  C  CB  . LEU D 1 496 ? 113.304 136.832 125.665 1.00 39.20  ? 489 LEU B CB  1 
ATOM   8764  C  CG  . LEU D 1 496 ? 113.130 137.729 126.893 1.00 39.20  ? 489 LEU B CG  1 
ATOM   8765  C  CD1 . LEU D 1 496 ? 113.506 136.988 128.159 1.00 39.20  ? 489 LEU B CD1 1 
ATOM   8766  C  CD2 . LEU D 1 496 ? 113.987 138.968 126.732 1.00 39.20  ? 489 LEU B CD2 1 
ATOM   8767  N  N   . LEU D 1 497 ? 110.426 135.542 127.064 1.00 41.94  ? 490 LEU B N   1 
ATOM   8768  C  CA  . LEU D 1 497 ? 109.042 135.847 127.517 1.00 41.94  ? 490 LEU B CA  1 
ATOM   8769  C  C   . LEU D 1 497 ? 109.102 136.897 128.630 1.00 41.94  ? 490 LEU B C   1 
ATOM   8770  O  O   . LEU D 1 497 ? 109.850 136.677 129.602 1.00 41.94  ? 490 LEU B O   1 
ATOM   8771  C  CB  . LEU D 1 497 ? 108.376 134.555 128.000 1.00 41.94  ? 490 LEU B CB  1 
ATOM   8772  C  CG  . LEU D 1 497 ? 107.869 133.625 126.897 1.00 41.94  ? 490 LEU B CG  1 
ATOM   8773  C  CD1 . LEU D 1 497 ? 108.985 132.735 126.374 1.00 41.94  ? 490 LEU B CD1 1 
ATOM   8774  C  CD2 . LEU D 1 497 ? 106.703 132.785 127.390 1.00 41.94  ? 490 LEU B CD2 1 
ATOM   8775  N  N   . LEU D 1 498 ? 108.346 137.990 128.488 1.00 43.77  ? 491 LEU B N   1 
ATOM   8776  C  CA  . LEU D 1 498 ? 108.395 139.093 129.487 1.00 43.77  ? 491 LEU B CA  1 
ATOM   8777  C  C   . LEU D 1 498 ? 106.997 139.333 130.068 1.00 43.77  ? 491 LEU B C   1 
ATOM   8778  O  O   . LEU D 1 498 ? 106.014 139.176 129.318 1.00 43.77  ? 491 LEU B O   1 
ATOM   8779  C  CB  . LEU D 1 498 ? 108.920 140.356 128.796 1.00 43.77  ? 491 LEU B CB  1 
ATOM   8780  C  CG  . LEU D 1 498 ? 110.363 140.283 128.301 1.00 43.77  ? 491 LEU B CG  1 
ATOM   8781  C  CD1 . LEU D 1 498 ? 110.799 141.614 127.708 1.00 43.77  ? 491 LEU B CD1 1 
ATOM   8782  C  CD2 . LEU D 1 498 ? 111.299 139.874 129.427 1.00 43.77  ? 491 LEU B CD2 1 
ATOM   8783  N  N   . ALA D 1 499 ? 106.922 139.702 131.350 1.00 46.34  ? 492 ALA B N   1 
ATOM   8784  C  CA  . ALA D 1 499 ? 105.618 140.001 131.988 1.00 46.34  ? 492 ALA B CA  1 
ATOM   8785  C  C   . ALA D 1 499 ? 105.162 141.405 131.582 1.00 46.34  ? 492 ALA B C   1 
ATOM   8786  O  O   . ALA D 1 499 ? 105.930 142.358 131.804 1.00 46.34  ? 492 ALA B O   1 
ATOM   8787  C  CB  . ALA D 1 499 ? 105.739 139.881 133.487 1.00 46.34  ? 492 ALA B CB  1 
ATOM   8788  N  N   . SER D 1 500 ? 103.952 141.516 131.021 1.00 54.45  ? 493 SER B N   1 
ATOM   8789  C  CA  . SER D 1 500 ? 103.399 142.834 130.612 1.00 54.45  ? 493 SER B CA  1 
ATOM   8790  C  C   . SER D 1 500 ? 101.933 142.940 131.061 1.00 54.45  ? 493 SER B C   1 
ATOM   8791  O  O   . SER D 1 500 ? 101.144 142.029 130.729 1.00 54.45  ? 493 SER B O   1 
ATOM   8792  C  CB  . SER D 1 500 ? 103.530 143.040 129.124 1.00 54.45  ? 493 SER B CB  1 
ATOM   8793  O  OG  . SER D 1 500 ? 104.893 143.005 128.726 1.00 54.45  ? 493 SER B OG  1 
ATOM   8794  N  N   . PRO D 1 501 ? 101.536 143.999 131.801 1.00 58.12  ? 494 PRO B N   1 
ATOM   8795  C  CA  . PRO D 1 501 ? 100.170 144.108 132.300 1.00 58.12  ? 494 PRO B CA  1 
ATOM   8796  C  C   . PRO D 1 501 ? 99.154  144.434 131.211 1.00 58.12  ? 494 PRO B C   1 
ATOM   8797  O  O   . PRO D 1 501 ? 97.985  144.016 131.331 1.00 58.12  ? 494 PRO B O   1 
ATOM   8798  C  CB  . PRO D 1 501 ? 100.280 145.229 133.347 1.00 58.12  ? 494 PRO B CB  1 
ATOM   8799  C  CG  . PRO D 1 501 ? 101.425 146.083 132.852 1.00 58.12  ? 494 PRO B CG  1 
ATOM   8800  C  CD  . PRO D 1 501 ? 102.389 145.112 132.190 1.00 58.12  ? 494 PRO B CD  1 
ATOM   8801  N  N   . ARG D 1 502 ? 99.582  145.176 130.185 1.00 30.00  ? 495 ARG B N   1 
ATOM   8802  C  CA  . ARG D 1 502 ? 98.678  145.558 129.069 1.00 30.00  ? 495 ARG B CA  1 
ATOM   8803  C  C   . ARG D 1 502 ? 97.998  144.300 128.508 1.00 30.00  ? 495 ARG B C   1 
ATOM   8804  O  O   . ARG D 1 502 ? 96.761  144.321 128.334 1.00 30.00  ? 495 ARG B O   1 
ATOM   8805  C  CB  . ARG D 1 502 ? 99.486  146.274 127.983 1.00 30.00  ? 495 ARG B CB  1 
ATOM   8806  C  CG  . ARG D 1 502 ? 100.846 145.635 127.738 1.00 30.00  ? 495 ARG B CG  1 
ATOM   8807  C  CD  . ARG D 1 502 ? 101.578 146.241 126.553 1.00 30.00  ? 495 ARG B CD  1 
ATOM   8808  N  NE  . ARG D 1 502 ? 102.944 145.720 126.435 1.00 30.00  ? 495 ARG B NE  1 
ATOM   8809  C  CZ  . ARG D 1 502 ? 103.417 145.067 125.381 1.00 30.00  ? 495 ARG B CZ  1 
ATOM   8810  N  NH1 . ARG D 1 502 ? 102.612 144.750 124.383 1.00 30.00  ? 495 ARG B NH1 1 
ATOM   8811  N  NH2 . ARG D 1 502 ? 104.694 144.732 125.331 1.00 30.00  ? 495 ARG B NH2 1 
ATOM   8812  N  N   . SER D 1 503 ? 98.782  143.255 128.232 1.00 67.59  ? 496 SER B N   1 
ATOM   8813  C  CA  . SER D 1 503 ? 98.222  141.988 127.692 1.00 67.59  ? 496 SER B CA  1 
ATOM   8814  C  C   . SER D 1 503 ? 97.026  141.549 128.549 1.00 67.59  ? 496 SER B C   1 
ATOM   8815  O  O   . SER D 1 503 ? 95.961  141.243 127.969 1.00 67.59  ? 496 SER B O   1 
ATOM   8816  C  CB  . SER D 1 503 ? 99.274  140.908 127.623 1.00 67.59  ? 496 SER B CB  1 
ATOM   8817  O  OG  . SER D 1 503 ? 100.446 141.287 128.332 1.00 67.59  ? 496 SER B OG  1 
ATOM   8818  N  N   . CYS D 1 504 ? 97.198  141.526 129.874 1.00 69.43  ? 497 CYS B N   1 
ATOM   8819  C  CA  . CYS D 1 504 ? 96.100  141.115 130.787 1.00 69.43  ? 497 CYS B CA  1 
ATOM   8820  C  C   . CYS D 1 504 ? 94.932  142.103 130.660 1.00 69.43  ? 497 CYS B C   1 
ATOM   8821  O  O   . CYS D 1 504 ? 93.768  141.645 130.679 1.00 69.43  ? 497 CYS B O   1 
ATOM   8822  C  CB  . CYS D 1 504 ? 96.581  141.068 132.232 1.00 69.43  ? 497 CYS B CB  1 
ATOM   8823  S  SG  . CYS D 1 504 ? 95.734  139.814 133.229 1.00 69.43  ? 497 CYS B SG  1 
ATOM   8824  N  N   . TYR D 1 505 ? 95.232  143.398 130.533 1.00 74.30  ? 498 TYR B N   1 
ATOM   8825  C  CA  . TYR D 1 505 ? 94.172  144.398 130.461 1.00 74.30  ? 498 TYR B CA  1 
ATOM   8826  C  C   . TYR D 1 505 ? 93.379  144.282 129.163 1.00 74.30  ? 498 TYR B C   1 
ATOM   8827  O  O   . TYR D 1 505 ? 92.158  144.463 129.164 1.00 74.30  ? 498 TYR B O   1 
ATOM   8828  C  CB  . TYR D 1 505 ? 94.754  145.798 130.628 1.00 74.30  ? 498 TYR B CB  1 
ATOM   8829  C  CG  . TYR D 1 505 ? 94.837  146.218 132.076 1.00 74.30  ? 498 TYR B CG  1 
ATOM   8830  C  CD1 . TYR D 1 505 ? 93.693  146.335 132.850 1.00 74.30  ? 498 TYR B CD1 1 
ATOM   8831  C  CD2 . TYR D 1 505 ? 96.060  146.484 132.674 1.00 74.30  ? 498 TYR B CD2 1 
ATOM   8832  C  CE1 . TYR D 1 505 ? 93.761  146.713 134.173 1.00 74.30  ? 498 TYR B CE1 1 
ATOM   8833  C  CE2 . TYR D 1 505 ? 96.140  146.862 133.997 1.00 74.30  ? 498 TYR B CE2 1 
ATOM   8834  C  CZ  . TYR D 1 505 ? 94.987  146.975 134.742 1.00 74.30  ? 498 TYR B CZ  1 
ATOM   8835  O  OH  . TYR D 1 505 ? 95.060  147.352 136.062 1.00 74.30  ? 498 TYR B OH  1 
ATOM   8836  N  N   . LYS D 1 506 ? 94.044  143.971 128.049 1.00 76.71  ? 499 LYS B N   1 
ATOM   8837  C  CA  . LYS D 1 506 ? 93.312  143.784 126.800 1.00 76.71  ? 499 LYS B CA  1 
ATOM   8838  C  C   . LYS D 1 506 ? 92.467  142.514 126.846 1.00 76.71  ? 499 LYS B C   1 
ATOM   8839  O  O   . LYS D 1 506 ? 91.333  142.497 126.348 1.00 76.71  ? 499 LYS B O   1 
ATOM   8840  C  CB  . LYS D 1 506 ? 94.279  143.778 125.611 1.00 76.71  ? 499 LYS B CB  1 
ATOM   8841  C  CG  . LYS D 1 506 ? 94.700  142.409 125.105 1.00 76.71  ? 499 LYS B CG  1 
ATOM   8842  C  CD  . LYS D 1 506 ? 95.195  142.480 123.669 1.00 76.71  ? 499 LYS B CD  1 
ATOM   8843  C  CE  . LYS D 1 506 ? 96.400  143.398 123.542 1.00 76.71  ? 499 LYS B CE  1 
ATOM   8844  N  NZ  . LYS D 1 506 ? 96.997  143.345 122.179 1.00 76.71  ? 499 LYS B NZ  1 
ATOM   8845  N  N   . LEU D 1 507 ? 92.986  141.450 127.469 1.00 78.33  ? 500 LEU B N   1 
ATOM   8846  C  CA  . LEU D 1 507 ? 92.182  140.245 127.644 1.00 78.33  ? 500 LEU B CA  1 
ATOM   8847  C  C   . LEU D 1 507 ? 90.943  140.537 128.478 1.00 78.33  ? 500 LEU B C   1 
ATOM   8848  O  O   . LEU D 1 507 ? 89.843  140.073 128.158 1.00 78.33  ? 500 LEU B O   1 
ATOM   8849  C  CB  . LEU D 1 507 ? 93.015  139.146 128.300 1.00 78.33  ? 500 LEU B CB  1 
ATOM   8850  C  CG  . LEU D 1 507 ? 92.308  137.832 128.624 1.00 78.33  ? 500 LEU B CG  1 
ATOM   8851  C  CD1 . LEU D 1 507 ? 91.827  137.175 127.346 1.00 78.33  ? 500 LEU B CD1 1 
ATOM   8852  C  CD2 . LEU D 1 507 ? 93.241  136.906 129.384 1.00 78.33  ? 500 LEU B CD2 1 
ATOM   8853  N  N   . PHE D 1 508 ? 91.102  141.314 129.549 1.00 83.36  ? 501 PHE B N   1 
ATOM   8854  C  CA  . PHE D 1 508 ? 89.968  141.636 130.404 1.00 83.36  ? 501 PHE B CA  1 
ATOM   8855  C  C   . PHE D 1 508 ? 88.980  142.553 129.693 1.00 83.36  ? 501 PHE B C   1 
ATOM   8856  O  O   . PHE D 1 508 ? 87.766  142.432 129.887 1.00 83.36  ? 501 PHE B O   1 
ATOM   8857  C  CB  . PHE D 1 508 ? 90.464  142.262 131.704 1.00 83.36  ? 501 PHE B CB  1 
ATOM   8858  C  CG  . PHE D 1 508 ? 91.046  141.268 132.666 1.00 83.36  ? 501 PHE B CG  1 
ATOM   8859  C  CD1 . PHE D 1 508 ? 90.978  139.912 132.404 1.00 83.36  ? 501 PHE B CD1 1 
ATOM   8860  C  CD2 . PHE D 1 508 ? 91.663  141.690 133.828 1.00 83.36  ? 501 PHE B CD2 1 
ATOM   8861  C  CE1 . PHE D 1 508 ? 91.510  138.997 133.282 1.00 83.36  ? 501 PHE B CE1 1 
ATOM   8862  C  CE2 . PHE D 1 508 ? 92.198  140.778 134.711 1.00 83.36  ? 501 PHE B CE2 1 
ATOM   8863  C  CZ  . PHE D 1 508 ? 92.123  139.429 134.438 1.00 83.36  ? 501 PHE B CZ  1 
ATOM   8864  N  N   . GLN D 1 509 ? 89.479  143.473 128.866 1.00 88.04  ? 502 GLN B N   1 
ATOM   8865  C  CA  . GLN D 1 509 ? 88.590  144.315 128.073 1.00 88.04  ? 502 GLN B CA  1 
ATOM   8866  C  C   . GLN D 1 509 ? 87.752  143.471 127.121 1.00 88.04  ? 502 GLN B C   1 
ATOM   8867  O  O   . GLN D 1 509 ? 86.546  143.699 126.968 1.00 88.04  ? 502 GLN B O   1 
ATOM   8868  C  CB  . GLN D 1 509 ? 89.401  145.355 127.299 1.00 88.04  ? 502 GLN B CB  1 
ATOM   8869  C  CG  . GLN D 1 509 ? 89.751  146.602 128.094 1.00 88.04  ? 502 GLN B CG  1 
ATOM   8870  C  CD  . GLN D 1 509 ? 88.548  147.206 128.790 1.00 88.04  ? 502 GLN B CD  1 
ATOM   8871  O  OE1 . GLN D 1 509 ? 88.471  147.223 130.017 1.00 88.04  ? 502 GLN B OE1 1 
ATOM   8872  N  NE2 . GLN D 1 509 ? 87.600  147.704 128.005 1.00 88.04  ? 502 GLN B NE2 1 
ATOM   8873  N  N   . GLU D 1 510 ? 88.379  142.488 126.471 1.00 92.57  ? 503 GLU B N   1 
ATOM   8874  C  CA  . GLU D 1 510 ? 87.623  141.588 125.604 1.00 92.57  ? 503 GLU B CA  1 
ATOM   8875  C  C   . GLU D 1 510 ? 86.602  140.781 126.400 1.00 92.57  ? 503 GLU B C   1 
ATOM   8876  O  O   . GLU D 1 510 ? 85.444  140.644 125.986 1.00 92.57  ? 503 GLU B O   1 
ATOM   8877  C  CB  . GLU D 1 510 ? 88.572  140.659 124.849 1.00 92.57  ? 503 GLU B CB  1 
ATOM   8878  C  CG  . GLU D 1 510 ? 89.587  141.380 123.983 1.00 92.57  ? 503 GLU B CG  1 
ATOM   8879  C  CD  . GLU D 1 510 ? 88.935  142.208 122.893 1.00 92.57  ? 503 GLU B CD  1 
ATOM   8880  O  OE1 . GLU D 1 510 ? 88.690  141.660 121.797 1.00 92.57  ? 503 GLU B OE1 1 
ATOM   8881  O  OE2 . GLU D 1 510 ? 88.671  143.406 123.128 1.00 92.57  ? 503 GLU B OE2 1 
ATOM   8882  N  N   . GLN D 1 511 ? 87.008  140.252 127.554 1.00 95.34  ? 504 GLN B N   1 
ATOM   8883  C  CA  . GLN D 1 511 ? 86.080  139.468 128.361 1.00 95.34  ? 504 GLN B CA  1 
ATOM   8884  C  C   . GLN D 1 511 ? 84.897  140.307 128.827 1.00 95.34  ? 504 GLN B C   1 
ATOM   8885  O  O   . GLN D 1 511 ? 83.780  139.791 128.948 1.00 95.34  ? 504 GLN B O   1 
ATOM   8886  C  CB  . GLN D 1 511 ? 86.808  138.857 129.557 1.00 95.34  ? 504 GLN B CB  1 
ATOM   8887  C  CG  . GLN D 1 511 ? 87.828  137.795 129.181 1.00 95.34  ? 504 GLN B CG  1 
ATOM   8888  C  CD  . GLN D 1 511 ? 87.296  136.817 128.155 1.00 95.34  ? 504 GLN B CD  1 
ATOM   8889  O  OE1 . GLN D 1 511 ? 86.311  136.120 128.398 1.00 95.34  ? 504 GLN B OE1 1 
ATOM   8890  N  NE2 . GLN D 1 511 ? 87.944  136.761 126.998 1.00 95.34  ? 504 GLN B NE2 1 
ATOM   8891  N  N   . GLN D 1 512 ? 85.119  141.594 129.099 1.00 99.06  ? 505 GLN B N   1 
ATOM   8892  C  CA  . GLN D 1 512 ? 84.020  142.455 129.521 1.00 99.06  ? 505 GLN B CA  1 
ATOM   8893  C  C   . GLN D 1 512 ? 83.109  142.811 128.352 1.00 99.06  ? 505 GLN B C   1 
ATOM   8894  O  O   . GLN D 1 512 ? 81.880  142.764 128.479 1.00 99.06  ? 505 GLN B O   1 
ATOM   8895  C  CB  . GLN D 1 512 ? 84.560  143.723 130.184 1.00 99.06  ? 505 GLN B CB  1 
ATOM   8896  C  CG  . GLN D 1 512 ? 83.476  144.544 130.867 1.00 99.06  ? 505 GLN B CG  1 
ATOM   8897  C  CD  . GLN D 1 512 ? 83.980  145.873 131.389 1.00 99.06  ? 505 GLN B CD  1 
ATOM   8898  O  OE1 . GLN D 1 512 ? 84.424  146.727 130.623 1.00 99.06  ? 505 GLN B OE1 1 
ATOM   8899  N  NE2 . GLN D 1 512 ? 83.906  146.057 132.703 1.00 99.06  ? 505 GLN B NE2 1 
ATOM   8900  N  N   . ASN D 1 513 ? 83.687  143.170 127.202 1.00 100.57 ? 506 ASN B N   1 
ATOM   8901  C  CA  . ASN D 1 513 ? 82.852  143.667 126.114 1.00 100.57 ? 506 ASN B CA  1 
ATOM   8902  C  C   . ASN D 1 513 ? 82.242  142.561 125.260 1.00 100.57 ? 506 ASN B C   1 
ATOM   8903  O  O   . ASN D 1 513 ? 81.409  142.863 124.399 1.00 100.57 ? 506 ASN B O   1 
ATOM   8904  C  CB  . ASN D 1 513 ? 83.637  144.665 125.245 1.00 100.57 ? 506 ASN B CB  1 
ATOM   8905  C  CG  . ASN D 1 513 ? 84.726  144.016 124.414 1.00 100.57 ? 506 ASN B CG  1 
ATOM   8906  O  OD1 . ASN D 1 513 ? 84.949  142.813 124.481 1.00 100.57 ? 506 ASN B OD1 1 
ATOM   8907  N  ND2 . ASN D 1 513 ? 85.417  144.824 123.619 1.00 100.57 ? 506 ASN B ND2 1 
ATOM   8908  N  N   . GLU D 1 514 ? 82.622  141.299 125.468 1.00 104.69 ? 507 GLU B N   1 
ATOM   8909  C  CA  . GLU D 1 514 ? 81.797  140.203 124.971 1.00 104.69 ? 507 GLU B CA  1 
ATOM   8910  C  C   . GLU D 1 514 ? 80.663  139.833 125.921 1.00 104.69 ? 507 GLU B C   1 
ATOM   8911  O  O   . GLU D 1 514 ? 79.888  138.924 125.606 1.00 104.69 ? 507 GLU B O   1 
ATOM   8912  C  CB  . GLU D 1 514 ? 82.642  138.960 124.663 1.00 104.69 ? 507 GLU B CB  1 
ATOM   8913  C  CG  . GLU D 1 514 ? 83.190  138.891 123.235 1.00 104.69 ? 507 GLU B CG  1 
ATOM   8914  C  CD  . GLU D 1 514 ? 84.008  140.095 122.819 1.00 104.69 ? 507 GLU B CD  1 
ATOM   8915  O  OE1 . GLU D 1 514 ? 83.620  140.764 121.839 1.00 104.69 ? 507 GLU B OE1 1 
ATOM   8916  O  OE2 . GLU D 1 514 ? 85.068  140.335 123.425 1.00 104.69 ? 507 GLU B OE2 1 
ATOM   8917  N  N   . GLY D 1 515 ? 80.543  140.505 127.064 1.00 106.77 ? 508 GLY B N   1 
ATOM   8918  C  CA  . GLY D 1 515 ? 79.392  140.351 127.928 1.00 106.77 ? 508 GLY B CA  1 
ATOM   8919  C  C   . GLY D 1 515 ? 79.577  139.451 129.130 1.00 106.77 ? 508 GLY B C   1 
ATOM   8920  O  O   . GLY D 1 515 ? 78.604  139.216 129.856 1.00 106.77 ? 508 GLY B O   1 
ATOM   8921  N  N   . HIS D 1 516 ? 80.783  138.940 129.365 1.00 107.41 ? 509 HIS B N   1 
ATOM   8922  C  CA  . HIS D 1 516 ? 81.053  138.055 130.497 1.00 107.41 ? 509 HIS B CA  1 
ATOM   8923  C  C   . HIS D 1 516 ? 81.801  138.767 131.614 1.00 107.41 ? 509 HIS B C   1 
ATOM   8924  O  O   . HIS D 1 516 ? 82.696  138.194 132.240 1.00 107.41 ? 509 HIS B O   1 
ATOM   8925  C  CB  . HIS D 1 516 ? 81.817  136.815 130.041 1.00 107.41 ? 509 HIS B CB  1 
ATOM   8926  C  CG  . HIS D 1 516 ? 81.424  136.324 128.682 1.00 107.41 ? 509 HIS B CG  1 
ATOM   8927  N  ND1 . HIS D 1 516 ? 81.772  136.978 127.520 1.00 107.41 ? 509 HIS B ND1 1 
ATOM   8928  C  CD2 . HIS D 1 516 ? 80.698  135.246 128.303 1.00 107.41 ? 509 HIS B CD2 1 
ATOM   8929  C  CE1 . HIS D 1 516 ? 81.286  136.319 126.483 1.00 107.41 ? 509 HIS B CE1 1 
ATOM   8930  N  NE2 . HIS D 1 516 ? 80.629  135.265 126.931 1.00 107.41 ? 509 HIS B NE2 1 
ATOM   8931  N  N   . GLY D 1 517 ? 81.451  140.026 131.885 1.00 103.51 ? 510 GLY B N   1 
ATOM   8932  C  CA  . GLY D 1 517 ? 82.058  140.746 132.991 1.00 103.51 ? 510 GLY B CA  1 
ATOM   8933  C  C   . GLY D 1 517 ? 81.723  140.172 134.353 1.00 103.51 ? 510 GLY B C   1 
ATOM   8934  O  O   . GLY D 1 517 ? 82.353  140.548 135.346 1.00 103.51 ? 510 GLY B O   1 
ATOM   8935  N  N   . GLU D 1 518 ? 80.739  139.276 134.424 1.00 104.03 ? 511 GLU B N   1 
ATOM   8936  C  CA  . GLU D 1 518 ? 80.377  138.632 135.680 1.00 104.03 ? 511 GLU B CA  1 
ATOM   8937  C  C   . GLU D 1 518 ? 81.399  137.601 136.139 1.00 104.03 ? 511 GLU B C   1 
ATOM   8938  O  O   . GLU D 1 518 ? 81.280  137.099 137.261 1.00 104.03 ? 511 GLU B O   1 
ATOM   8939  C  CB  . GLU D 1 518 ? 79.007  137.959 135.551 1.00 104.03 ? 511 GLU B CB  1 
ATOM   8940  C  CG  . GLU D 1 518 ? 77.891  138.877 135.080 1.00 104.03 ? 511 GLU B CG  1 
ATOM   8941  C  CD  . GLU D 1 518 ? 77.391  139.798 136.176 1.00 104.03 ? 511 GLU B CD  1 
ATOM   8942  O  OE1 . GLU D 1 518 ? 77.025  139.292 137.257 1.00 104.03 ? 511 GLU B OE1 1 
ATOM   8943  O  OE2 . GLU D 1 518 ? 77.356  141.025 135.954 1.00 104.03 ? 511 GLU B OE2 1 
ATOM   8944  N  N   . ALA D 1 519 ? 82.384  137.267 135.304 1.00 101.64 ? 512 ALA B N   1 
ATOM   8945  C  CA  . ALA D 1 519 ? 83.358  136.243 135.660 1.00 101.64 ? 512 ALA B CA  1 
ATOM   8946  C  C   . ALA D 1 519 ? 84.124  136.636 136.915 1.00 101.64 ? 512 ALA B C   1 
ATOM   8947  O  O   . ALA D 1 519 ? 84.531  137.790 137.082 1.00 101.64 ? 512 ALA B O   1 
ATOM   8948  C  CB  . ALA D 1 519 ? 84.329  136.012 134.501 1.00 101.64 ? 512 ALA B CB  1 
ATOM   8949  N  N   . LEU D 1 520 ? 84.321  135.667 137.803 1.00 99.92  ? 513 LEU B N   1 
ATOM   8950  C  CA  . LEU D 1 520 ? 84.962  135.893 139.090 1.00 99.92  ? 513 LEU B CA  1 
ATOM   8951  C  C   . LEU D 1 520 ? 86.363  135.297 139.086 1.00 99.92  ? 513 LEU B C   1 
ATOM   8952  O  O   . LEU D 1 520 ? 86.529  134.088 138.897 1.00 99.92  ? 513 LEU B O   1 
ATOM   8953  C  CB  . LEU D 1 520 ? 84.138  135.284 140.229 1.00 99.92  ? 513 LEU B CB  1 
ATOM   8954  C  CG  . LEU D 1 520 ? 82.766  135.902 140.507 1.00 99.92  ? 513 LEU B CG  1 
ATOM   8955  C  CD1 . LEU D 1 520 ? 81.672  135.119 139.799 1.00 99.92  ? 513 LEU B CD1 1 
ATOM   8956  C  CD2 . LEU D 1 520 ? 82.500  135.968 142.002 1.00 99.92  ? 513 LEU B CD2 1 
ATOM   8957  N  N   . LEU D 1 521 ? 87.361  136.148 139.295 1.00 96.64  ? 514 LEU B N   1 
ATOM   8958  C  CA  . LEU D 1 521 ? 88.735  135.715 139.481 1.00 96.64  ? 514 LEU B CA  1 
ATOM   8959  C  C   . LEU D 1 521 ? 88.900  135.171 140.893 1.00 96.64  ? 514 LEU B C   1 
ATOM   8960  O  O   . LEU D 1 521 ? 88.297  135.688 141.843 1.00 96.64  ? 514 LEU B O   1 
ATOM   8961  C  CB  . LEU D 1 521 ? 89.700  136.878 139.238 1.00 96.64  ? 514 LEU B CB  1 
ATOM   8962  C  CG  . LEU D 1 521 ? 91.103  136.599 138.689 1.00 96.64  ? 514 LEU B CG  1 
ATOM   8963  C  CD1 . LEU D 1 521 ? 91.693  137.869 138.104 1.00 96.64  ? 514 LEU B CD1 1 
ATOM   8964  C  CD2 . LEU D 1 521 ? 92.025  136.040 139.756 1.00 96.64  ? 514 LEU B CD2 1 
ATOM   8965  N  N   . PHE D 1 522 ? 89.727  134.126 141.013 1.00 98.26  ? 515 PHE B N   1 
ATOM   8966  C  CA  . PHE D 1 522 ? 89.955  133.385 142.258 1.00 98.26  ? 515 PHE B CA  1 
ATOM   8967  C  C   . PHE D 1 522 ? 88.711  132.598 142.670 1.00 98.26  ? 515 PHE B C   1 
ATOM   8968  O  O   . PHE D 1 522 ? 88.346  132.558 143.845 1.00 98.26  ? 515 PHE B O   1 
ATOM   8969  C  CB  . PHE D 1 522 ? 90.421  134.302 143.392 1.00 98.26  ? 515 PHE B CB  1 
ATOM   8970  C  CG  . PHE D 1 522 ? 91.752  134.945 143.139 1.00 98.26  ? 515 PHE B CG  1 
ATOM   8971  C  CD1 . PHE D 1 522 ? 92.825  134.195 142.694 1.00 98.26  ? 515 PHE B CD1 1 
ATOM   8972  C  CD2 . PHE D 1 522 ? 91.932  136.300 143.354 1.00 98.26  ? 515 PHE B CD2 1 
ATOM   8973  C  CE1 . PHE D 1 522 ? 94.050  134.787 142.461 1.00 98.26  ? 515 PHE B CE1 1 
ATOM   8974  C  CE2 . PHE D 1 522 ? 93.156  136.895 143.124 1.00 98.26  ? 515 PHE B CE2 1 
ATOM   8975  C  CZ  . PHE D 1 522 ? 94.217  136.137 142.677 1.00 98.26  ? 515 PHE B CZ  1 
ATOM   8976  N  N   . GLU D 1 523 ? 88.057  131.969 141.693 1.00 101.02 ? 516 GLU B N   1 
ATOM   8977  C  CA  . GLU D 1 523 ? 86.892  131.144 141.994 1.00 101.02 ? 516 GLU B CA  1 
ATOM   8978  C  C   . GLU D 1 523 ? 87.294  129.838 142.670 1.00 101.02 ? 516 GLU B C   1 
ATOM   8979  O  O   . GLU D 1 523 ? 86.641  129.402 143.624 1.00 101.02 ? 516 GLU B O   1 
ATOM   8980  C  CB  . GLU D 1 523 ? 86.101  130.864 140.718 1.00 101.02 ? 516 GLU B CB  1 
ATOM   8981  C  CG  . GLU D 1 523 ? 86.961  130.751 139.472 1.00 101.02 ? 516 GLU B CG  1 
ATOM   8982  C  CD  . GLU D 1 523 ? 86.137  130.606 138.211 1.00 101.02 ? 516 GLU B CD  1 
ATOM   8983  O  OE1 . GLU D 1 523 ? 85.319  129.665 138.137 1.00 101.02 ? 516 GLU B OE1 1 
ATOM   8984  O  OE2 . GLU D 1 523 ? 86.300  131.438 137.295 1.00 101.02 ? 516 GLU B OE2 1 
ATOM   8985  N  N   . GLY D 1 524 ? 88.360  129.199 142.183 1.00 103.64 ? 517 GLY B N   1 
ATOM   8986  C  CA  . GLY D 1 524 ? 88.781  127.934 142.763 1.00 103.64 ? 517 GLY B CA  1 
ATOM   8987  C  C   . GLY D 1 524 ? 89.220  128.068 144.209 1.00 103.64 ? 517 GLY B C   1 
ATOM   8988  O  O   . GLY D 1 524 ? 88.946  127.194 145.035 1.00 103.64 ? 517 GLY B O   1 
ATOM   8989  N  N   . ILE D 1 525 ? 89.907  129.157 144.531 1.00 107.64 ? 518 ILE B N   1 
ATOM   8990  C  CA  . ILE D 1 525 ? 90.354  129.403 145.898 1.00 107.64 ? 518 ILE B CA  1 
ATOM   8991  C  C   . ILE D 1 525 ? 89.181  129.932 146.712 1.00 107.64 ? 518 ILE B C   1 
ATOM   8992  O  O   . ILE D 1 525 ? 88.510  130.890 146.311 1.00 107.64 ? 518 ILE B O   1 
ATOM   8993  C  CB  . ILE D 1 525 ? 91.534  130.387 145.913 1.00 107.64 ? 518 ILE B CB  1 
ATOM   8994  C  CG1 . ILE D 1 525 ? 92.748  129.780 145.206 1.00 107.64 ? 518 ILE B CG1 1 
ATOM   8995  C  CG2 . ILE D 1 525 ? 91.881  130.782 147.339 1.00 107.64 ? 518 ILE B CG2 1 
ATOM   8996  C  CD1 . ILE D 1 525 ? 92.973  128.314 145.513 1.00 107.64 ? 518 ILE B CD1 1 
ATOM   8997  N  N   . LYS D 1 526 ? 88.931  129.306 147.861 1.00 112.01 ? 519 LYS B N   1 
ATOM   8998  C  CA  . LYS D 1 526 ? 87.813  129.672 148.722 1.00 112.01 ? 519 LYS B CA  1 
ATOM   8999  C  C   . LYS D 1 526 ? 88.181  130.710 149.773 1.00 112.01 ? 519 LYS B C   1 
ATOM   9000  O  O   . LYS D 1 526 ? 87.386  131.615 150.045 1.00 112.01 ? 519 LYS B O   1 
ATOM   9001  C  CB  . LYS D 1 526 ? 87.252  128.427 149.416 1.00 112.01 ? 519 LYS B CB  1 
ATOM   9002  C  CG  . LYS D 1 526 ? 86.714  127.373 148.463 1.00 112.01 ? 519 LYS B CG  1 
ATOM   9003  C  CD  . LYS D 1 526 ? 86.134  126.190 149.220 1.00 112.01 ? 519 LYS B CD  1 
ATOM   9004  C  CE  . LYS D 1 526 ? 85.638  125.113 148.268 1.00 112.01 ? 519 LYS B CE  1 
ATOM   9005  N  NZ  . LYS D 1 526 ? 85.067  123.949 148.998 1.00 112.01 ? 519 LYS B NZ  1 
ATOM   9006  N  N   . LYS D 1 527 ? 89.366  130.595 150.378 1.00 108.69 ? 520 LYS B N   1 
ATOM   9007  C  CA  . LYS D 1 527 ? 89.759  131.536 151.422 1.00 108.69 ? 520 LYS B CA  1 
ATOM   9008  C  C   . LYS D 1 527 ? 89.913  132.949 150.872 1.00 108.69 ? 520 LYS B C   1 
ATOM   9009  O  O   . LYS D 1 527 ? 89.429  133.912 151.479 1.00 108.69 ? 520 LYS B O   1 
ATOM   9010  C  CB  . LYS D 1 527 ? 91.056  131.076 152.084 1.00 108.69 ? 520 LYS B CB  1 
ATOM   9011  C  CG  . LYS D 1 527 ? 90.982  129.686 152.695 1.00 108.69 ? 520 LYS B CG  1 
ATOM   9012  C  CD  . LYS D 1 527 ? 92.244  129.360 153.477 1.00 108.69 ? 520 LYS B CD  1 
ATOM   9013  C  CE  . LYS D 1 527 ? 92.328  127.876 153.797 1.00 108.69 ? 520 LYS B CE  1 
ATOM   9014  N  NZ  . LYS D 1 527 ? 93.620  127.520 154.448 1.00 108.69 ? 520 LYS B NZ  1 
ATOM   9015  N  N   . LYS D 1 528 ? 90.577  133.096 149.730 1.00 106.14 ? 521 LYS B N   1 
ATOM   9016  C  CA  . LYS D 1 528 ? 90.765  134.414 149.146 1.00 106.14 ? 521 LYS B CA  1 
ATOM   9017  C  C   . LYS D 1 528 ? 89.477  134.897 148.487 1.00 106.14 ? 521 LYS B C   1 
ATOM   9018  O  O   . LYS D 1 528 ? 88.700  134.113 147.937 1.00 106.14 ? 521 LYS B O   1 
ATOM   9019  C  CB  . LYS D 1 528 ? 91.903  134.394 148.126 1.00 106.14 ? 521 LYS B CB  1 
ATOM   9020  C  CG  . LYS D 1 528 ? 92.465  135.770 147.804 1.00 106.14 ? 521 LYS B CG  1 
ATOM   9021  C  CD  . LYS D 1 528 ? 93.729  135.674 146.968 1.00 106.14 ? 521 LYS B CD  1 
ATOM   9022  C  CE  . LYS D 1 528 ? 94.514  136.975 147.005 1.00 106.14 ? 521 LYS B CE  1 
ATOM   9023  N  NZ  . LYS D 1 528 ? 95.849  136.838 146.360 1.00 106.14 ? 521 LYS B NZ  1 
ATOM   9024  N  N   . LYS D 1 529 ? 89.257  136.206 148.554 1.00 109.51 ? 522 LYS B N   1 
ATOM   9025  C  CA  . LYS D 1 529 ? 88.045  136.790 147.998 1.00 109.51 ? 522 LYS B CA  1 
ATOM   9026  C  C   . LYS D 1 529 ? 88.072  136.751 146.476 1.00 109.51 ? 522 LYS B C   1 
ATOM   9027  O  O   . LYS D 1 529 ? 89.098  137.025 145.846 1.00 109.51 ? 522 LYS B O   1 
ATOM   9028  C  CB  . LYS D 1 529 ? 87.882  138.231 148.482 1.00 109.51 ? 522 LYS B CB  1 
ATOM   9029  C  CG  . LYS D 1 529 ? 87.847  138.375 149.994 1.00 109.51 ? 522 LYS B CG  1 
ATOM   9030  C  CD  . LYS D 1 529 ? 87.687  139.828 150.407 1.00 109.51 ? 522 LYS B CD  1 
ATOM   9031  C  CE  . LYS D 1 529 ? 87.689  139.974 151.920 1.00 109.51 ? 522 LYS B CE  1 
ATOM   9032  N  NZ  . LYS D 1 529 ? 87.509  141.390 152.341 1.00 109.51 ? 522 LYS B NZ  1 
ATOM   9033  N  N   . GLN D 1 530 ? 86.932  136.405 145.885 1.00 104.82 ? 523 GLN B N   1 
ATOM   9034  C  CA  . GLN D 1 530 ? 86.766  136.421 144.439 1.00 104.82 ? 523 GLN B CA  1 
ATOM   9035  C  C   . GLN D 1 530 ? 86.501  137.847 143.978 1.00 104.82 ? 523 GLN B C   1 
ATOM   9036  O  O   . GLN D 1 530 ? 85.778  138.598 144.639 1.00 104.82 ? 523 GLN B O   1 
ATOM   9037  C  CB  . GLN D 1 530 ? 85.610  135.510 144.026 1.00 104.82 ? 523 GLN B CB  1 
ATOM   9038  C  CG  . GLN D 1 530 ? 85.382  134.342 144.974 1.00 104.82 ? 523 GLN B CG  1 
ATOM   9039  C  CD  . GLN D 1 530 ? 84.279  133.414 144.505 1.00 104.82 ? 523 GLN B CD  1 
ATOM   9040  O  OE1 . GLN D 1 530 ? 84.529  132.435 143.804 1.00 104.82 ? 523 GLN B OE1 1 
ATOM   9041  N  NE2 . GLN D 1 530 ? 83.047  133.719 144.895 1.00 104.82 ? 523 GLN B NE2 1 
ATOM   9042  N  N   . GLN D 1 531 ? 87.086  138.222 142.842 1.00 99.04  ? 524 GLN B N   1 
ATOM   9043  C  CA  . GLN D 1 531 ? 86.957  139.588 142.342 1.00 99.04  ? 524 GLN B CA  1 
ATOM   9044  C  C   . GLN D 1 531 ? 86.311  139.587 140.966 1.00 99.04  ? 524 GLN B C   1 
ATOM   9045  O  O   . GLN D 1 531 ? 86.704  138.809 140.094 1.00 99.04  ? 524 GLN B O   1 
ATOM   9046  C  CB  . GLN D 1 531 ? 88.314  140.297 142.290 1.00 99.04  ? 524 GLN B CB  1 
ATOM   9047  C  CG  . GLN D 1 531 ? 88.978  140.445 143.646 1.00 99.04  ? 524 GLN B CG  1 
ATOM   9048  C  CD  . GLN D 1 531 ? 90.384  140.998 143.554 1.00 99.04  ? 524 GLN B CD  1 
ATOM   9049  O  OE1 . GLN D 1 531 ? 90.591  142.121 143.094 1.00 99.04  ? 524 GLN B OE1 1 
ATOM   9050  N  NE2 . GLN D 1 531 ? 91.360  140.214 143.994 1.00 99.04  ? 524 GLN B NE2 1 
ATOM   9051  N  N   . LYS D 1 532 ? 85.324  140.456 140.774 1.00 98.56  ? 525 LYS B N   1 
ATOM   9052  C  CA  . LYS D 1 532 ? 84.620  140.513 139.505 1.00 98.56  ? 525 LYS B CA  1 
ATOM   9053  C  C   . LYS D 1 532 ? 85.382  141.392 138.513 1.00 98.56  ? 525 LYS B C   1 
ATOM   9054  O  O   . LYS D 1 532 ? 86.229  142.207 138.886 1.00 98.56  ? 525 LYS B O   1 
ATOM   9055  C  CB  . LYS D 1 532 ? 83.196  141.028 139.707 1.00 98.56  ? 525 LYS B CB  1 
ATOM   9056  C  CG  . LYS D 1 532 ? 82.363  140.141 140.625 1.00 98.56  ? 525 LYS B CG  1 
ATOM   9057  C  CD  . LYS D 1 532 ? 81.045  140.791 141.017 1.00 98.56  ? 525 LYS B CD  1 
ATOM   9058  C  CE  . LYS D 1 532 ? 80.302  141.325 139.806 1.00 98.56  ? 525 LYS B CE  1 
ATOM   9059  N  NZ  . LYS D 1 532 ? 80.193  140.291 138.738 1.00 98.56  ? 525 LYS B NZ  1 
ATOM   9060  N  N   . ILE D 1 533 ? 85.064  141.213 137.229 1.00 94.13  ? 526 ILE B N   1 
ATOM   9061  C  CA  . ILE D 1 533 ? 85.843  141.847 136.168 1.00 94.13  ? 526 ILE B CA  1 
ATOM   9062  C  C   . ILE D 1 533 ? 85.652  143.361 136.174 1.00 94.13  ? 526 ILE B C   1 
ATOM   9063  O  O   . ILE D 1 533 ? 86.606  144.120 135.959 1.00 94.13  ? 526 ILE B O   1 
ATOM   9064  C  CB  . ILE D 1 533 ? 85.478  141.229 134.805 1.00 94.13  ? 526 ILE B CB  1 
ATOM   9065  C  CG1 . ILE D 1 533 ? 86.063  139.822 134.686 1.00 94.13  ? 526 ILE B CG1 1 
ATOM   9066  C  CG2 . ILE D 1 533 ? 85.975  142.099 133.664 1.00 94.13  ? 526 ILE B CG2 1 
ATOM   9067  C  CD1 . ILE D 1 533 ? 87.568  139.796 134.565 1.00 94.13  ? 526 ILE B CD1 1 
ATOM   9068  N  N   . LYS D 1 534 ? 84.425  143.828 136.412 1.00 93.70  ? 527 LYS B N   1 
ATOM   9069  C  CA  . LYS D 1 534 ? 84.171  145.265 136.364 1.00 93.70  ? 527 LYS B CA  1 
ATOM   9070  C  C   . LYS D 1 534 ? 84.962  146.013 137.429 1.00 93.70  ? 527 LYS B C   1 
ATOM   9071  O  O   . LYS D 1 534 ? 85.510  147.087 137.159 1.00 93.70  ? 527 LYS B O   1 
ATOM   9072  C  CB  . LYS D 1 534 ? 82.677  145.553 136.507 1.00 93.70  ? 527 LYS B CB  1 
ATOM   9073  C  CG  . LYS D 1 534 ? 81.764  144.538 135.847 1.00 93.70  ? 527 LYS B CG  1 
ATOM   9074  C  CD  . LYS D 1 534 ? 80.420  144.476 136.550 1.00 93.70  ? 527 LYS B CD  1 
ATOM   9075  C  CE  . LYS D 1 534 ? 79.602  143.289 136.074 1.00 93.70  ? 527 LYS B CE  1 
ATOM   9076  N  NZ  . LYS D 1 534 ? 80.257  141.995 136.391 1.00 93.70  ? 527 LYS B NZ  1 
ATOM   9077  N  N   . ASN D 1 535 ? 85.033  145.467 138.645 1.00 92.69  ? 528 ASN B N   1 
ATOM   9078  C  CA  . ASN D 1 535 ? 85.744  146.158 139.718 1.00 92.69  ? 528 ASN B CA  1 
ATOM   9079  C  C   . ASN D 1 535 ? 87.231  146.284 139.409 1.00 92.69  ? 528 ASN B C   1 
ATOM   9080  O  O   . ASN D 1 535 ? 87.821  147.361 139.566 1.00 92.69  ? 528 ASN B O   1 
ATOM   9081  C  CB  . ASN D 1 535 ? 85.531  145.431 141.046 1.00 92.69  ? 528 ASN B CB  1 
ATOM   9082  C  CG  . ASN D 1 535 ? 84.123  144.898 141.200 1.00 92.69  ? 528 ASN B CG  1 
ATOM   9083  O  OD1 . ASN D 1 535 ? 83.910  143.689 141.281 1.00 92.69  ? 528 ASN B OD1 1 
ATOM   9084  N  ND2 . ASN D 1 535 ? 83.150  145.800 141.246 1.00 92.69  ? 528 ASN B ND2 1 
ATOM   9085  N  N   . ILE D 1 536 ? 87.855  145.194 138.960 1.00 87.31  ? 529 ILE B N   1 
ATOM   9086  C  CA  . ILE D 1 536 ? 89.287  145.234 138.678 1.00 87.31  ? 529 ILE B CA  1 
ATOM   9087  C  C   . ILE D 1 536 ? 89.571  146.116 137.468 1.00 87.31  ? 529 ILE B C   1 
ATOM   9088  O  O   . ILE D 1 536 ? 90.594  146.810 137.417 1.00 87.31  ? 529 ILE B O   1 
ATOM   9089  C  CB  . ILE D 1 536 ? 89.846  143.809 138.504 1.00 87.31  ? 529 ILE B CB  1 
ATOM   9090  C  CG1 . ILE D 1 536 ? 91.343  143.850 138.197 1.00 87.31  ? 529 ILE B CG1 1 
ATOM   9091  C  CG2 . ILE D 1 536 ? 89.112  143.058 137.413 1.00 87.31  ? 529 ILE B CG2 1 
ATOM   9092  C  CD1 . ILE D 1 536 ? 91.972  142.486 138.108 1.00 87.31  ? 529 ILE B CD1 1 
ATOM   9093  N  N   . LEU D 1 537 ? 88.674  146.117 136.479 1.00 89.56  ? 530 LEU B N   1 
ATOM   9094  C  CA  . LEU D 1 537 ? 88.861  146.988 135.325 1.00 89.56  ? 530 LEU B CA  1 
ATOM   9095  C  C   . LEU D 1 537 ? 88.676  148.462 135.666 1.00 89.56  ? 530 LEU B C   1 
ATOM   9096  O  O   . LEU D 1 537 ? 89.365  149.307 135.088 1.00 89.56  ? 530 LEU B O   1 
ATOM   9097  C  CB  . LEU D 1 537 ? 87.906  146.594 134.199 1.00 89.56  ? 530 LEU B CB  1 
ATOM   9098  C  CG  . LEU D 1 537 ? 88.358  145.410 133.348 1.00 89.56  ? 530 LEU B CG  1 
ATOM   9099  C  CD1 . LEU D 1 537 ? 87.373  145.147 132.223 1.00 89.56  ? 530 LEU B CD1 1 
ATOM   9100  C  CD2 . LEU D 1 537 ? 89.745  145.671 132.795 1.00 89.56  ? 530 LEU B CD2 1 
ATOM   9101  N  N   . SER D 1 538 ? 87.770  148.789 136.586 1.00 90.53  ? 531 SER B N   1 
ATOM   9102  C  CA  . SER D 1 538 ? 87.517  150.175 136.950 1.00 90.53  ? 531 SER B CA  1 
ATOM   9103  C  C   . SER D 1 538 ? 88.390  150.664 138.097 1.00 90.53  ? 531 SER B C   1 
ATOM   9104  O  O   . SER D 1 538 ? 88.323  151.851 138.437 1.00 90.53  ? 531 SER B O   1 
ATOM   9105  C  CB  . SER D 1 538 ? 86.042  150.361 137.319 1.00 90.53  ? 531 SER B CB  1 
ATOM   9106  O  OG  . SER D 1 538 ? 85.289  150.793 136.201 1.00 90.53  ? 531 SER B OG  1 
ATOM   9107  N  N   . ASN D 1 539 ? 89.192  149.791 138.703 1.00 84.53  ? 532 ASN B N   1 
ATOM   9108  C  CA  . ASN D 1 539 ? 90.117  150.232 139.737 1.00 84.53  ? 532 ASN B CA  1 
ATOM   9109  C  C   . ASN D 1 539 ? 91.138  151.202 139.154 1.00 84.53  ? 532 ASN B C   1 
ATOM   9110  O  O   . ASN D 1 539 ? 91.642  151.006 138.044 1.00 84.53  ? 532 ASN B O   1 
ATOM   9111  C  CB  . ASN D 1 539 ? 90.825  149.029 140.363 1.00 84.53  ? 532 ASN B CB  1 
ATOM   9112  C  CG  . ASN D 1 539 ? 91.494  149.366 141.682 1.00 84.53  ? 532 ASN B CG  1 
ATOM   9113  O  OD1 . ASN D 1 539 ? 91.711  150.534 142.004 1.00 84.53  ? 532 ASN B OD1 1 
ATOM   9114  N  ND2 . ASN D 1 539 ? 91.824  148.338 142.455 1.00 84.53  ? 532 ASN B ND2 1 
ATOM   9115  N  N   . LYS D 1 540 ? 91.439  152.255 139.910 1.00 82.69  ? 533 LYS B N   1 
ATOM   9116  C  CA  . LYS D 1 540 ? 92.328  153.322 139.461 1.00 82.69  ? 533 LYS B CA  1 
ATOM   9117  C  C   . LYS D 1 540 ? 93.723  153.228 140.062 1.00 82.69  ? 533 LYS B C   1 
ATOM   9118  O  O   . LYS D 1 540 ? 94.717  153.419 139.349 1.00 82.69  ? 533 LYS B O   1 
ATOM   9119  C  CB  . LYS D 1 540 ? 91.716  154.685 139.799 1.00 82.69  ? 533 LYS B CB  1 
ATOM   9120  C  CG  . LYS D 1 540 ? 92.670  155.859 139.651 1.00 82.69  ? 533 LYS B CG  1 
ATOM   9121  C  CD  . LYS D 1 540 ? 91.932  157.191 139.684 1.00 82.69  ? 533 LYS B CD  1 
ATOM   9122  C  CE  . LYS D 1 540 ? 90.618  157.140 138.915 1.00 82.69  ? 533 LYS B CE  1 
ATOM   9123  N  NZ  . LYS D 1 540 ? 90.800  156.714 137.497 1.00 82.69  ? 533 LYS B NZ  1 
ATOM   9124  N  N   . THR D 1 541 ? 93.822  152.944 141.362 1.00 77.35  ? 534 THR B N   1 
ATOM   9125  C  CA  . THR D 1 541 ? 95.131  152.762 141.978 1.00 77.35  ? 534 THR B CA  1 
ATOM   9126  C  C   . THR D 1 541 ? 95.864  151.582 141.355 1.00 77.35  ? 534 THR B C   1 
ATOM   9127  O  O   . THR D 1 541 ? 97.077  151.647 141.121 1.00 77.35  ? 534 THR B O   1 
ATOM   9128  C  CB  . THR D 1 541 ? 94.980  152.564 143.487 1.00 77.35  ? 534 THR B CB  1 
ATOM   9129  O  OG1 . THR D 1 541 ? 94.000  151.551 143.743 1.00 77.35  ? 534 THR B OG1 1 
ATOM   9130  C  CG2 . THR D 1 541 ? 94.544  153.860 144.151 1.00 77.35  ? 534 THR B CG2 1 
ATOM   9131  N  N   . LEU D 1 542 ? 95.141  150.493 141.081 1.00 73.15  ? 535 LEU B N   1 
ATOM   9132  C  CA  . LEU D 1 542 ? 95.756  149.348 140.419 1.00 73.15  ? 535 LEU B CA  1 
ATOM   9133  C  C   . LEU D 1 542 ? 96.241  149.715 139.024 1.00 73.15  ? 535 LEU B C   1 
ATOM   9134  O  O   . LEU D 1 542 ? 97.319  149.285 138.604 1.00 73.15  ? 535 LEU B O   1 
ATOM   9135  C  CB  . LEU D 1 542 ? 94.773  148.181 140.356 1.00 73.15  ? 535 LEU B CB  1 
ATOM   9136  C  CG  . LEU D 1 542 ? 95.360  146.894 139.777 1.00 73.15  ? 535 LEU B CG  1 
ATOM   9137  C  CD1 . LEU D 1 542 ? 96.287  146.236 140.781 1.00 73.15  ? 535 LEU B CD1 1 
ATOM   9138  C  CD2 . LEU D 1 542 ? 94.258  145.938 139.360 1.00 73.15  ? 535 LEU B CD2 1 
ATOM   9139  N  N   . ARG D 1 543 ? 95.456  150.506 138.288 1.00 76.24  ? 536 ARG B N   1 
ATOM   9140  C  CA  . ARG D 1 543 ? 95.886  150.936 136.961 1.00 76.24  ? 536 ARG B CA  1 
ATOM   9141  C  C   . ARG D 1 543 ? 97.149  151.783 137.036 1.00 76.24  ? 536 ARG B C   1 
ATOM   9142  O  O   . ARG D 1 543 ? 98.063  151.620 136.222 1.00 76.24  ? 536 ARG B O   1 
ATOM   9143  C  CB  . ARG D 1 543 ? 94.764  151.707 136.266 1.00 76.24  ? 536 ARG B CB  1 
ATOM   9144  C  CG  . ARG D 1 543 ? 95.166  152.320 134.935 1.00 76.24  ? 536 ARG B CG  1 
ATOM   9145  C  CD  . ARG D 1 543 ? 93.984  152.435 133.987 1.00 76.24  ? 536 ARG B CD  1 
ATOM   9146  N  NE  . ARG D 1 543 ? 93.954  151.352 133.012 1.00 76.24  ? 536 ARG B NE  1 
ATOM   9147  C  CZ  . ARG D 1 543 ? 93.050  150.382 132.996 1.00 76.24  ? 536 ARG B CZ  1 
ATOM   9148  N  NH1 . ARG D 1 543 ? 92.085  150.322 133.900 1.00 76.24  ? 536 ARG B NH1 1 
ATOM   9149  N  NH2 . ARG D 1 543 ? 93.115  149.450 132.051 1.00 76.24  ? 536 ARG B NH2 1 
ATOM   9150  N  N   . GLU D 1 544 ? 97.219  152.691 138.010 1.00 72.61  ? 537 GLU B N   1 
ATOM   9151  C  CA  . GLU D 1 544 ? 98.413  153.522 138.167 1.00 72.61  ? 537 GLU B CA  1 
ATOM   9152  C  C   . GLU D 1 544 ? 99.635  152.672 138.510 1.00 72.61  ? 537 GLU B C   1 
ATOM   9153  O  O   . GLU D 1 544 ? 100.722 152.849 137.936 1.00 72.61  ? 537 GLU B O   1 
ATOM   9154  C  CB  . GLU D 1 544 ? 98.160  154.577 139.245 1.00 72.61  ? 537 GLU B CB  1 
ATOM   9155  C  CG  . GLU D 1 544 ? 97.087  155.600 138.917 1.00 72.61  ? 537 GLU B CG  1 
ATOM   9156  C  CD  . GLU D 1 544 ? 97.366  156.375 137.643 1.00 72.61  ? 537 GLU B CD  1 
ATOM   9157  O  OE1 . GLU D 1 544 ? 98.536  156.737 137.402 1.00 72.61  ? 537 GLU B OE1 1 
ATOM   9158  O  OE2 . GLU D 1 544 ? 96.410  156.622 136.880 1.00 72.61  ? 537 GLU B OE2 1 
ATOM   9159  N  N   . HIS D 1 545 ? 99.467  151.732 139.442 1.00 65.45  ? 538 HIS B N   1 
ATOM   9160  C  CA  . HIS D 1 545 ? 100.573 150.863 139.828 1.00 65.45  ? 538 HIS B CA  1 
ATOM   9161  C  C   . HIS D 1 545 ? 101.039 150.015 138.652 1.00 65.45  ? 538 HIS B C   1 
ATOM   9162  O  O   . HIS D 1 545 ? 102.245 149.837 138.439 1.00 65.45  ? 538 HIS B O   1 
ATOM   9163  C  CB  . HIS D 1 545 ? 100.152 149.978 140.999 1.00 65.45  ? 538 HIS B CB  1 
ATOM   9164  C  CG  . HIS D 1 545 ? 99.816  150.740 142.243 1.00 65.45  ? 538 HIS B CG  1 
ATOM   9165  N  ND1 . HIS D 1 545 ? 99.457  150.121 143.420 1.00 65.45  ? 538 HIS B ND1 1 
ATOM   9166  C  CD2 . HIS D 1 545 ? 99.790  152.070 142.495 1.00 65.45  ? 538 HIS B CD2 1 
ATOM   9167  C  CE1 . HIS D 1 545 ? 99.220  151.036 144.343 1.00 65.45  ? 538 HIS B CE1 1 
ATOM   9168  N  NE2 . HIS D 1 545 ? 99.415  152.227 143.807 1.00 65.45  ? 538 HIS B NE2 1 
ATOM   9169  N  N   . ASN D 1 546 ? 100.095 149.493 137.868 1.00 63.19  ? 539 ASN B N   1 
ATOM   9170  C  CA  . ASN D 1 546 ? 100.469 148.691 136.714 1.00 63.19  ? 539 ASN B CA  1 
ATOM   9171  C  C   . ASN D 1 546 ? 101.093 149.542 135.617 1.00 63.19  ? 539 ASN B C   1 
ATOM   9172  O  O   . ASN D 1 546 ? 101.922 149.043 134.858 1.00 63.19  ? 539 ASN B O   1 
ATOM   9173  C  CB  . ASN D 1 546 ? 99.258  147.930 136.187 1.00 63.19  ? 539 ASN B CB  1 
ATOM   9174  C  CG  . ASN D 1 546 ? 99.024  146.640 136.935 1.00 63.19  ? 539 ASN B CG  1 
ATOM   9175  O  OD1 . ASN D 1 546 ? 99.546  145.590 136.562 1.00 63.19  ? 539 ASN B OD1 1 
ATOM   9176  N  ND2 . ASN D 1 546 ? 98.249  146.710 138.009 1.00 63.19  ? 539 ASN B ND2 1 
ATOM   9177  N  N   . SER D 1 547 ? 100.729 150.822 135.525 1.00 60.69  ? 540 SER B N   1 
ATOM   9178  C  CA  . SER D 1 547 ? 101.422 151.709 134.596 1.00 60.69  ? 540 SER B CA  1 
ATOM   9179  C  C   . SER D 1 547 ? 102.881 151.886 134.998 1.00 60.69  ? 540 SER B C   1 
ATOM   9180  O  O   . SER D 1 547 ? 103.779 151.849 134.146 1.00 60.69  ? 540 SER B O   1 
ATOM   9181  C  CB  . SER D 1 547 ? 100.716 153.062 134.532 1.00 60.69  ? 540 SER B CB  1 
ATOM   9182  O  OG  . SER D 1 547 ? 101.461 153.984 133.758 1.00 60.69  ? 540 SER B OG  1 
ATOM   9183  N  N   . PHE D 1 548 ? 103.138 152.072 136.293 1.00 56.99  ? 541 PHE B N   1 
ATOM   9184  C  CA  . PHE D 1 548 ? 104.523 152.164 136.758 1.00 56.99  ? 541 PHE B CA  1 
ATOM   9185  C  C   . PHE D 1 548 ? 105.286 150.871 136.474 1.00 56.99  ? 541 PHE B C   1 
ATOM   9186  O  O   . PHE D 1 548 ? 106.437 150.892 136.006 1.00 56.99  ? 541 PHE B O   1 
ATOM   9187  C  CB  . PHE D 1 548 ? 104.554 152.486 138.251 1.00 56.99  ? 541 PHE B CB  1 
ATOM   9188  C  CG  . PHE D 1 548 ? 105.911 152.344 138.873 1.00 56.99  ? 541 PHE B CG  1 
ATOM   9189  C  CD1 . PHE D 1 548 ? 107.009 152.986 138.331 1.00 56.99  ? 541 PHE B CD1 1 
ATOM   9190  C  CD2 . PHE D 1 548 ? 106.090 151.560 140.000 1.00 56.99  ? 541 PHE B CD2 1 
ATOM   9191  C  CE1 . PHE D 1 548 ? 108.257 152.853 138.902 1.00 56.99  ? 541 PHE B CE1 1 
ATOM   9192  C  CE2 . PHE D 1 548 ? 107.337 151.423 140.574 1.00 56.99  ? 541 PHE B CE2 1 
ATOM   9193  C  CZ  . PHE D 1 548 ? 108.421 152.069 140.024 1.00 56.99  ? 541 PHE B CZ  1 
ATOM   9194  N  N   . VAL D 1 549 ? 104.653 149.732 136.758 1.00 54.46  ? 542 VAL B N   1 
ATOM   9195  C  CA  . VAL D 1 549 ? 105.296 148.443 136.523 1.00 54.46  ? 542 VAL B CA  1 
ATOM   9196  C  C   . VAL D 1 549 ? 105.564 148.247 135.035 1.00 54.46  ? 542 VAL B C   1 
ATOM   9197  O  O   . VAL D 1 549 ? 106.607 147.710 134.640 1.00 54.46  ? 542 VAL B O   1 
ATOM   9198  C  CB  . VAL D 1 549 ? 104.432 147.314 137.113 1.00 54.46  ? 542 VAL B CB  1 
ATOM   9199  C  CG1 . VAL D 1 549 ? 104.674 146.005 136.387 1.00 54.46  ? 542 VAL B CG1 1 
ATOM   9200  C  CG2 . VAL D 1 549 ? 104.706 147.175 138.599 1.00 54.46  ? 542 VAL B CG2 1 
ATOM   9201  N  N   . GLU D 1 550 ? 104.637 148.697 134.188 1.00 55.33  ? 543 GLU B N   1 
ATOM   9202  C  CA  . GLU D 1 550 ? 104.829 148.616 132.746 1.00 55.33  ? 543 GLU B CA  1 
ATOM   9203  C  C   . GLU D 1 550 ? 105.995 149.482 132.297 1.00 55.33  ? 543 GLU B C   1 
ATOM   9204  O  O   . GLU D 1 550 ? 106.743 149.101 131.393 1.00 55.33  ? 543 GLU B O   1 
ATOM   9205  C  CB  . GLU D 1 550 ? 103.546 149.032 132.027 1.00 55.33  ? 543 GLU B CB  1 
ATOM   9206  C  CG  . GLU D 1 550 ? 103.715 149.252 130.538 1.00 55.33  ? 543 GLU B CG  1 
ATOM   9207  C  CD  . GLU D 1 550 ? 103.679 150.719 130.163 1.00 55.33  ? 543 GLU B CD  1 
ATOM   9208  O  OE1 . GLU D 1 550 ? 103.899 151.566 131.052 1.00 55.33  ? 543 GLU B OE1 1 
ATOM   9209  O  OE2 . GLU D 1 550 ? 103.429 151.026 128.979 1.00 55.33  ? 543 GLU B OE2 1 
ATOM   9210  N  N   . ARG D 1 551 ? 106.155 150.660 132.901 1.00 55.34  ? 544 ARG B N   1 
ATOM   9211  C  CA  . ARG D 1 551 ? 107.297 151.506 132.558 1.00 55.34  ? 544 ARG B CA  1 
ATOM   9212  C  C   . ARG D 1 551 ? 108.615 150.821 132.908 1.00 55.34  ? 544 ARG B C   1 
ATOM   9213  O  O   . ARG D 1 551 ? 109.567 150.833 132.113 1.00 55.34  ? 544 ARG B O   1 
ATOM   9214  C  CB  . ARG D 1 551 ? 107.178 152.851 133.270 1.00 55.34  ? 544 ARG B CB  1 
ATOM   9215  C  CG  . ARG D 1 551 ? 108.069 153.935 132.703 1.00 55.34  ? 544 ARG B CG  1 
ATOM   9216  C  CD  . ARG D 1 551 ? 107.310 155.247 132.605 1.00 55.34  ? 544 ARG B CD  1 
ATOM   9217  N  NE  . ARG D 1 551 ? 107.033 155.814 133.919 1.00 55.34  ? 544 ARG B NE  1 
ATOM   9218  C  CZ  . ARG D 1 551 ? 106.051 156.667 134.176 1.00 55.34  ? 544 ARG B CZ  1 
ATOM   9219  N  NH1 . ARG D 1 551 ? 105.223 157.072 133.228 1.00 55.34  ? 544 ARG B NH1 1 
ATOM   9220  N  NH2 . ARG D 1 551 ? 105.897 157.123 135.416 1.00 55.34  ? 544 ARG B NH2 1 
ATOM   9221  N  N   . CYS D 1 552 ? 108.683 150.206 134.093 1.00 50.07  ? 545 CYS B N   1 
ATOM   9222  C  CA  . CYS D 1 552 ? 109.894 149.472 134.463 1.00 50.07  ? 545 CYS B CA  1 
ATOM   9223  C  C   . CYS D 1 552 ? 110.155 148.313 133.506 1.00 50.07  ? 545 CYS B C   1 
ATOM   9224  O  O   . CYS D 1 552 ? 111.299 148.081 133.083 1.00 50.07  ? 545 CYS B O   1 
ATOM   9225  C  CB  . CYS D 1 552 ? 109.787 148.963 135.899 1.00 50.07  ? 545 CYS B CB  1 
ATOM   9226  S  SG  . CYS D 1 552 ? 109.596 150.252 137.141 1.00 50.07  ? 545 CYS B SG  1 
ATOM   9227  N  N   . ILE D 1 553 ? 109.100 147.577 133.149 1.00 47.75  ? 546 ILE B N   1 
ATOM   9228  C  CA  . ILE D 1 553 ? 109.246 146.450 132.233 1.00 47.75  ? 546 ILE B CA  1 
ATOM   9229  C  C   . ILE D 1 553 ? 109.708 146.933 130.864 1.00 47.75  ? 546 ILE B C   1 
ATOM   9230  O  O   . ILE D 1 553 ? 110.513 146.274 130.200 1.00 47.75  ? 546 ILE B O   1 
ATOM   9231  C  CB  . ILE D 1 553 ? 107.924 145.665 132.140 1.00 47.75  ? 546 ILE B CB  1 
ATOM   9232  C  CG1 . ILE D 1 553 ? 107.720 144.810 133.392 1.00 47.75  ? 546 ILE B CG1 1 
ATOM   9233  C  CG2 . ILE D 1 553 ? 107.900 144.801 130.892 1.00 47.75  ? 546 ILE B CG2 1 
ATOM   9234  C  CD1 . ILE D 1 553 ? 108.501 143.528 133.384 1.00 47.75  ? 546 ILE B CD1 1 
ATOM   9235  N  N   . ASP D 1 554 ? 109.204 148.086 130.419 1.00 49.77  ? 547 ASP B N   1 
ATOM   9236  C  CA  . ASP D 1 554 ? 109.614 148.632 129.131 1.00 49.77  ? 547 ASP B CA  1 
ATOM   9237  C  C   . ASP D 1 554 ? 111.088 149.006 129.137 1.00 49.77  ? 547 ASP B C   1 
ATOM   9238  O  O   . ASP D 1 554 ? 111.810 148.743 128.165 1.00 49.77  ? 547 ASP B O   1 
ATOM   9239  C  CB  . ASP D 1 554 ? 108.759 149.850 128.786 1.00 49.77  ? 547 ASP B CB  1 
ATOM   9240  C  CG  . ASP D 1 554 ? 107.850 149.606 127.602 1.00 49.77  ? 547 ASP B CG  1 
ATOM   9241  O  OD1 . ASP D 1 554 ? 107.672 148.431 127.222 1.00 49.77  ? 547 ASP B OD1 1 
ATOM   9242  O  OD2 . ASP D 1 554 ? 107.314 150.590 127.051 1.00 49.77  ? 547 ASP B OD2 1 
ATOM   9243  N  N   . TRP D 1 555 ? 111.554 149.630 130.222 1.00 44.52  ? 548 TRP B N   1 
ATOM   9244  C  CA  . TRP D 1 555 ? 112.974 149.956 130.315 1.00 44.52  ? 548 TRP B CA  1 
ATOM   9245  C  C   . TRP D 1 555 ? 113.824 148.690 130.263 1.00 44.52  ? 548 TRP B C   1 
ATOM   9246  O  O   . TRP D 1 555 ? 114.835 148.632 129.549 1.00 44.52  ? 548 TRP B O   1 
ATOM   9247  C  CB  . TRP D 1 555 ? 113.257 150.740 131.595 1.00 44.52  ? 548 TRP B CB  1 
ATOM   9248  C  CG  . TRP D 1 555 ? 114.712 151.031 131.794 1.00 44.52  ? 548 TRP B CG  1 
ATOM   9249  C  CD1 . TRP D 1 555 ? 115.564 150.394 132.646 1.00 44.52  ? 548 TRP B CD1 1 
ATOM   9250  C  CD2 . TRP D 1 555 ? 115.485 152.038 131.134 1.00 44.52  ? 548 TRP B CD2 1 
ATOM   9251  N  NE1 . TRP D 1 555 ? 116.822 150.937 132.553 1.00 44.52  ? 548 TRP B NE1 1 
ATOM   9252  C  CE2 . TRP D 1 555 ? 116.798 151.950 131.631 1.00 44.52  ? 548 TRP B CE2 1 
ATOM   9253  C  CE3 . TRP D 1 555 ? 115.194 153.003 130.167 1.00 44.52  ? 548 TRP B CE3 1 
ATOM   9254  C  CZ2 . TRP D 1 555 ? 117.818 152.790 131.198 1.00 44.52  ? 548 TRP B CZ2 1 
ATOM   9255  C  CZ3 . TRP D 1 555 ? 116.207 153.835 129.737 1.00 44.52  ? 548 TRP B CZ3 1 
ATOM   9256  C  CH2 . TRP D 1 555 ? 117.503 153.723 130.252 1.00 44.52  ? 548 TRP B CH2 1 
ATOM   9257  N  N   . ASN D 1 556 ? 113.417 147.656 131.004 1.00 43.98  ? 549 ASN B N   1 
ATOM   9258  C  CA  . ASN D 1 556 ? 114.182 146.411 130.982 1.00 43.98  ? 549 ASN B CA  1 
ATOM   9259  C  C   . ASN D 1 556 ? 114.135 145.739 129.614 1.00 43.98  ? 549 ASN B C   1 
ATOM   9260  O  O   . ASN D 1 556 ? 115.126 145.140 129.185 1.00 43.98  ? 549 ASN B O   1 
ATOM   9261  C  CB  . ASN D 1 556 ? 113.675 145.459 132.061 1.00 43.98  ? 549 ASN B CB  1 
ATOM   9262  C  CG  . ASN D 1 556 ? 114.157 145.847 133.437 1.00 43.98  ? 549 ASN B CG  1 
ATOM   9263  O  OD1 . ASN D 1 556 ? 115.079 145.239 133.978 1.00 43.98  ? 549 ASN B OD1 1 
ATOM   9264  N  ND2 . ASN D 1 556 ? 113.540 146.870 134.011 1.00 43.98  ? 549 ASN B ND2 1 
ATOM   9265  N  N   . ARG D 1 557 ? 112.997 145.823 128.923 1.00 46.00  ? 550 ARG B N   1 
ATOM   9266  C  CA  . ARG D 1 557 ? 112.894 145.255 127.583 1.00 46.00  ? 550 ARG B CA  1 
ATOM   9267  C  C   . ARG D 1 557 ? 113.831 145.959 126.616 1.00 46.00  ? 550 ARG B C   1 
ATOM   9268  O  O   . ARG D 1 557 ? 114.480 145.311 125.791 1.00 46.00  ? 550 ARG B O   1 
ATOM   9269  C  CB  . ARG D 1 557 ? 111.454 145.343 127.081 1.00 46.00  ? 550 ARG B CB  1 
ATOM   9270  C  CG  . ARG D 1 557 ? 111.256 144.812 125.675 1.00 46.00  ? 550 ARG B CG  1 
ATOM   9271  C  CD  . ARG D 1 557 ? 110.247 145.655 124.918 1.00 46.00  ? 550 ARG B CD  1 
ATOM   9272  N  NE  . ARG D 1 557 ? 109.501 144.880 123.934 1.00 46.00  ? 550 ARG B NE  1 
ATOM   9273  C  CZ  . ARG D 1 557 ? 108.481 144.085 124.223 1.00 46.00  ? 550 ARG B CZ  1 
ATOM   9274  N  NH1 . ARG D 1 557 ? 108.062 143.921 125.467 1.00 46.00  ? 550 ARG B NH1 1 
ATOM   9275  N  NH2 . ARG D 1 557 ? 107.862 143.440 123.238 1.00 46.00  ? 550 ARG B NH2 1 
ATOM   9276  N  N   . GLU D 1 558 ? 113.905 147.290 126.694 1.00 45.55  ? 551 GLU B N   1 
ATOM   9277  C  CA  . GLU D 1 558 ? 114.841 148.015 125.839 1.00 45.55  ? 551 GLU B CA  1 
ATOM   9278  C  C   . GLU D 1 558 ? 116.281 147.647 126.168 1.00 45.55  ? 551 GLU B C   1 
ATOM   9279  O  O   . GLU D 1 558 ? 117.110 147.488 125.264 1.00 45.55  ? 551 GLU B O   1 
ATOM   9280  C  CB  . GLU D 1 558 ? 114.628 149.520 125.971 1.00 45.55  ? 551 GLU B CB  1 
ATOM   9281  C  CG  . GLU D 1 558 ? 113.299 149.996 125.425 1.00 45.55  ? 551 GLU B CG  1 
ATOM   9282  C  CD  . GLU D 1 558 ? 113.430 150.579 124.036 1.00 45.55  ? 551 GLU B CD  1 
ATOM   9283  O  OE1 . GLU D 1 558 ? 112.607 151.441 123.672 1.00 45.55  ? 551 GLU B OE1 1 
ATOM   9284  O  OE2 . GLU D 1 558 ? 114.360 150.176 123.307 1.00 45.55  ? 551 GLU B OE2 1 
ATOM   9285  N  N   . LEU D 1 559 ? 116.594 147.496 127.456 1.00 41.65  ? 552 LEU B N   1 
ATOM   9286  C  CA  . LEU D 1 559 ? 117.944 147.095 127.842 1.00 41.65  ? 552 LEU B CA  1 
ATOM   9287  C  C   . LEU D 1 559 ? 118.297 145.728 127.266 1.00 41.65  ? 552 LEU B C   1 
ATOM   9288  O  O   . LEU D 1 559 ? 119.381 145.537 126.699 1.00 41.65  ? 552 LEU B O   1 
ATOM   9289  C  CB  . LEU D 1 559 ? 118.068 147.094 129.365 1.00 41.65  ? 552 LEU B CB  1 
ATOM   9290  C  CG  . LEU D 1 559 ? 119.469 146.970 129.961 1.00 41.65  ? 552 LEU B CG  1 
ATOM   9291  C  CD1 . LEU D 1 559 ? 120.489 147.698 129.109 1.00 41.65  ? 552 LEU B CD1 1 
ATOM   9292  C  CD2 . LEU D 1 559 ? 119.472 147.513 131.376 1.00 41.65  ? 552 LEU B CD2 1 
ATOM   9293  N  N   . LEU D 1 560 ? 117.381 144.764 127.389 1.00 39.75  ? 553 LEU B N   1 
ATOM   9294  C  CA  . LEU D 1 560 ? 117.636 143.427 126.861 1.00 39.75  ? 553 LEU B CA  1 
ATOM   9295  C  C   . LEU D 1 560 ? 117.728 143.433 125.341 1.00 39.75  ? 553 LEU B C   1 
ATOM   9296  O  O   . LEU D 1 560 ? 118.560 142.727 124.764 1.00 39.75  ? 553 LEU B O   1 
ATOM   9297  C  CB  . LEU D 1 560 ? 116.550 142.459 127.324 1.00 39.75  ? 553 LEU B CB  1 
ATOM   9298  C  CG  . LEU D 1 560 ? 116.680 141.946 128.755 1.00 39.75  ? 553 LEU B CG  1 
ATOM   9299  C  CD1 . LEU D 1 560 ? 115.391 141.282 129.197 1.00 39.75  ? 553 LEU B CD1 1 
ATOM   9300  C  CD2 . LEU D 1 560 ? 117.842 140.982 128.856 1.00 39.75  ? 553 LEU B CD2 1 
ATOM   9301  N  N   . LYS D 1 561 ? 116.876 144.214 124.674 1.00 39.70  ? 554 LYS B N   1 
ATOM   9302  C  CA  . LYS D 1 561 ? 116.924 144.292 123.220 1.00 39.70  ? 554 LYS B CA  1 
ATOM   9303  C  C   . LYS D 1 561 ? 118.236 144.895 122.742 1.00 39.70  ? 554 LYS B C   1 
ATOM   9304  O  O   . LYS D 1 561 ? 118.769 144.485 121.706 1.00 39.70  ? 554 LYS B O   1 
ATOM   9305  C  CB  . LYS D 1 561 ? 115.734 145.104 122.710 1.00 39.70  ? 554 LYS B CB  1 
ATOM   9306  C  CG  . LYS D 1 561 ? 115.815 145.519 121.258 1.00 39.70  ? 554 LYS B CG  1 
ATOM   9307  C  CD  . LYS D 1 561 ? 114.428 145.585 120.642 1.00 39.70  ? 554 LYS B CD  1 
ATOM   9308  C  CE  . LYS D 1 561 ? 113.642 146.765 121.183 1.00 39.70  ? 554 LYS B CE  1 
ATOM   9309  N  NZ  . LYS D 1 561 ? 112.369 146.968 120.441 1.00 39.70  ? 554 LYS B NZ  1 
ATOM   9310  N  N   . ARG D 1 562 ? 118.776 145.861 123.487 1.00 41.99  ? 555 ARG B N   1 
ATOM   9311  C  CA  . ARG D 1 562 ? 120.068 146.430 123.126 1.00 41.99  ? 555 ARG B CA  1 
ATOM   9312  C  C   . ARG D 1 562 ? 121.204 145.445 123.387 1.00 41.99  ? 555 ARG B C   1 
ATOM   9313  O  O   . ARG D 1 562 ? 122.144 145.352 122.592 1.00 41.99  ? 555 ARG B O   1 
ATOM   9314  C  CB  . ARG D 1 562 ? 120.299 147.729 123.897 1.00 41.99  ? 555 ARG B CB  1 
ATOM   9315  C  CG  . ARG D 1 562 ? 121.648 148.382 123.643 1.00 41.99  ? 555 ARG B CG  1 
ATOM   9316  C  CD  . ARG D 1 562 ? 121.617 149.857 124.007 1.00 41.99  ? 555 ARG B CD  1 
ATOM   9317  N  NE  . ARG D 1 562 ? 122.080 150.088 125.370 1.00 41.99  ? 555 ARG B NE  1 
ATOM   9318  C  CZ  . ARG D 1 562 ? 121.357 150.664 126.321 1.00 41.99  ? 555 ARG B CZ  1 
ATOM   9319  N  NH1 . ARG D 1 562 ? 120.122 151.080 126.094 1.00 41.99  ? 555 ARG B NH1 1 
ATOM   9320  N  NH2 . ARG D 1 562 ? 121.886 150.825 127.531 1.00 41.99  ? 555 ARG B NH2 1 
ATOM   9321  N  N   . GLU D 1 563 ? 121.133 144.697 124.491 1.00 40.71  ? 556 GLU B N   1 
ATOM   9322  C  CA  . GLU D 1 563 ? 122.265 143.883 124.920 1.00 40.71  ? 556 GLU B CA  1 
ATOM   9323  C  C   . GLU D 1 563 ? 122.266 142.464 124.361 1.00 40.71  ? 556 GLU B C   1 
ATOM   9324  O  O   . GLU D 1 563 ? 123.291 141.783 124.467 1.00 40.71  ? 556 GLU B O   1 
ATOM   9325  C  CB  . GLU D 1 563 ? 122.312 143.820 126.449 1.00 40.71  ? 556 GLU B CB  1 
ATOM   9326  C  CG  . GLU D 1 563 ? 122.557 145.164 127.117 1.00 40.71  ? 556 GLU B CG  1 
ATOM   9327  C  CD  . GLU D 1 563 ? 124.021 145.555 127.139 1.00 40.71  ? 556 GLU B CD  1 
ATOM   9328  O  OE1 . GLU D 1 563 ? 124.609 145.739 126.053 1.00 40.71  ? 556 GLU B OE1 1 
ATOM   9329  O  OE2 . GLU D 1 563 ? 124.583 145.685 128.246 1.00 40.71  ? 556 GLU B OE2 1 
ATOM   9330  N  N   . LEU D 1 564 ? 121.164 141.994 123.776 1.00 38.03  ? 557 LEU B N   1 
ATOM   9331  C  CA  . LEU D 1 564 ? 121.104 140.639 123.238 1.00 38.03  ? 557 LEU B CA  1 
ATOM   9332  C  C   . LEU D 1 564 ? 120.741 140.599 121.760 1.00 38.03  ? 557 LEU B C   1 
ATOM   9333  O  O   . LEU D 1 564 ? 120.429 139.521 121.242 1.00 38.03  ? 557 LEU B O   1 
ATOM   9334  C  CB  . LEU D 1 564 ? 120.112 139.788 124.038 1.00 38.03  ? 557 LEU B CB  1 
ATOM   9335  C  CG  . LEU D 1 564 ? 120.497 139.479 125.484 1.00 38.03  ? 557 LEU B CG  1 
ATOM   9336  C  CD1 . LEU D 1 564 ? 119.492 138.532 126.110 1.00 38.03  ? 557 LEU B CD1 1 
ATOM   9337  C  CD2 . LEU D 1 564 ? 121.897 138.901 125.552 1.00 38.03  ? 557 LEU B CD2 1 
ATOM   9338  N  N   . GLY D 1 565 ? 120.772 141.735 121.071 1.00 38.71  ? 558 GLY B N   1 
ATOM   9339  C  CA  . GLY D 1 565 ? 120.532 141.746 119.636 1.00 38.71  ? 558 GLY B CA  1 
ATOM   9340  C  C   . GLY D 1 565 ? 119.182 141.199 119.231 1.00 38.71  ? 558 GLY B C   1 
ATOM   9341  O  O   . GLY D 1 565 ? 119.078 140.490 118.224 1.00 38.71  ? 558 GLY B O   1 
ATOM   9342  N  N   . LEU D 1 566 ? 118.143 141.509 119.997 1.00 39.42  ? 559 LEU B N   1 
ATOM   9343  C  CA  . LEU D 1 566 ? 116.807 141.005 119.723 1.00 39.42  ? 559 LEU B CA  1 
ATOM   9344  C  C   . LEU D 1 566 ? 116.016 141.990 118.877 1.00 39.42  ? 559 LEU B C   1 
ATOM   9345  O  O   . LEU D 1 566 ? 116.235 143.202 118.926 1.00 39.42  ? 559 LEU B O   1 
ATOM   9346  C  CB  . LEU D 1 566 ? 116.054 140.737 121.027 1.00 39.42  ? 559 LEU B CB  1 
ATOM   9347  C  CG  . LEU D 1 566 ? 116.565 139.614 121.925 1.00 39.42  ? 559 LEU B CG  1 
ATOM   9348  C  CD1 . LEU D 1 566 ? 115.733 139.551 123.184 1.00 39.42  ? 559 LEU B CD1 1 
ATOM   9349  C  CD2 . LEU D 1 566 ? 116.519 138.289 121.192 1.00 39.42  ? 559 LEU B CD2 1 
ATOM   9350  N  N   . ALA D 1 567 ? 115.095 141.452 118.093 1.00 42.23  ? 560 ALA B N   1 
ATOM   9351  C  CA  . ALA D 1 567 ? 114.086 142.239 117.413 1.00 42.23  ? 560 ALA B CA  1 
ATOM   9352  C  C   . ALA D 1 567 ? 112.778 142.117 118.188 1.00 42.23  ? 560 ALA B C   1 
ATOM   9353  O  O   . ALA D 1 567 ? 112.728 141.529 119.271 1.00 42.23  ? 560 ALA B O   1 
ATOM   9354  C  CB  . ALA D 1 567 ? 113.944 141.782 115.961 1.00 42.23  ? 560 ALA B CB  1 
ATOM   9355  N  N   . GLU D 1 568 ? 111.702 142.676 117.641 1.00 46.24  ? 561 GLU B N   1 
ATOM   9356  C  CA  . GLU D 1 568 ? 110.404 142.528 118.283 1.00 46.24  ? 561 GLU B CA  1 
ATOM   9357  C  C   . GLU D 1 568 ? 109.777 141.162 118.040 1.00 46.24  ? 561 GLU B C   1 
ATOM   9358  O  O   . GLU D 1 568 ? 108.768 140.842 118.677 1.00 46.24  ? 561 GLU B O   1 
ATOM   9359  C  CB  . GLU D 1 568 ? 109.449 143.624 117.808 1.00 46.24  ? 561 GLU B CB  1 
ATOM   9360  C  CG  . GLU D 1 568 ? 109.217 144.720 118.832 1.00 46.24  ? 561 GLU B CG  1 
ATOM   9361  C  CD  . GLU D 1 568 ? 108.531 144.209 120.086 1.00 46.24  ? 561 GLU B CD  1 
ATOM   9362  O  OE1 . GLU D 1 568 ? 107.427 143.638 119.970 1.00 46.24  ? 561 GLU B OE1 1 
ATOM   9363  O  OE2 . GLU D 1 568 ? 109.096 144.380 121.186 1.00 46.24  ? 561 GLU B OE2 1 
ATOM   9364  N  N   . SER D 1 569 ? 110.342 140.356 117.146 1.00 44.89  ? 562 SER B N   1 
ATOM   9365  C  CA  . SER D 1 569 ? 109.804 139.037 116.846 1.00 44.89  ? 562 SER B CA  1 
ATOM   9366  C  C   . SER D 1 569 ? 110.288 137.957 117.803 1.00 44.89  ? 562 SER B C   1 
ATOM   9367  O  O   . SER D 1 569 ? 109.725 136.857 117.803 1.00 44.89  ? 562 SER B O   1 
ATOM   9368  C  CB  . SER D 1 569 ? 110.163 138.635 115.412 1.00 44.89  ? 562 SER B CB  1 
ATOM   9369  O  OG  . SER D 1 569 ? 109.689 139.593 114.481 1.00 44.89  ? 562 SER B OG  1 
ATOM   9370  N  N   . ASP D 1 570 ? 111.308 138.236 118.615 1.00 42.48  ? 563 ASP B N   1 
ATOM   9371  C  CA  . ASP D 1 570 ? 111.870 137.259 119.536 1.00 42.48  ? 563 ASP B CA  1 
ATOM   9372  C  C   . ASP D 1 570 ? 111.384 137.440 120.966 1.00 42.48  ? 563 ASP B C   1 
ATOM   9373  O  O   . ASP D 1 570 ? 111.881 136.759 121.867 1.00 42.48  ? 563 ASP B O   1 
ATOM   9374  C  CB  . ASP D 1 570 ? 113.398 137.316 119.505 1.00 42.48  ? 563 ASP B CB  1 
ATOM   9375  C  CG  . ASP D 1 570 ? 113.969 136.889 118.173 1.00 42.48  ? 563 ASP B CG  1 
ATOM   9376  O  OD1 . ASP D 1 570 ? 113.715 135.740 117.760 1.00 42.48  ? 563 ASP B OD1 1 
ATOM   9377  O  OD2 . ASP D 1 570 ? 114.672 137.700 117.537 1.00 42.48  ? 563 ASP B OD2 1 
ATOM   9378  N  N   . ILE D 1 571 ? 110.433 138.338 121.200 1.00 41.56  ? 564 ILE B N   1 
ATOM   9379  C  CA  . ILE D 1 571 ? 109.947 138.635 122.541 1.00 41.56  ? 564 ILE B CA  1 
ATOM   9380  C  C   . ILE D 1 571 ? 108.445 138.395 122.575 1.00 41.56  ? 564 ILE B C   1 
ATOM   9381  O  O   . ILE D 1 571 ? 107.711 138.902 121.720 1.00 41.56  ? 564 ILE B O   1 
ATOM   9382  C  CB  . ILE D 1 571 ? 110.290 140.074 122.962 1.00 41.56  ? 564 ILE B CB  1 
ATOM   9383  C  CG1 . ILE D 1 571 ? 111.730 140.143 123.467 1.00 41.56  ? 564 ILE B CG1 1 
ATOM   9384  C  CG2 . ILE D 1 571 ? 109.347 140.555 124.043 1.00 41.56  ? 564 ILE B CG2 1 
ATOM   9385  C  CD1 . ILE D 1 571 ? 112.282 141.541 123.543 1.00 41.56  ? 564 ILE B CD1 1 
ATOM   9386  N  N   . ILE D 1 572 ? 108.029 137.592 123.562 1.00 46.87  ? 565 ILE B N   1 
ATOM   9387  C  CA  . ILE D 1 572 ? 106.590 137.245 123.727 1.00 46.87  ? 565 ILE B CA  1 
ATOM   9388  C  C   . ILE D 1 572 ? 106.113 137.813 125.065 1.00 46.87  ? 565 ILE B C   1 
ATOM   9389  O  O   . ILE D 1 572 ? 106.841 137.661 126.063 1.00 46.87  ? 565 ILE B O   1 
ATOM   9390  C  CB  . ILE D 1 572 ? 106.410 135.715 123.670 1.00 46.87  ? 565 ILE B CB  1 
ATOM   9391  C  CG1 . ILE D 1 572 ? 106.993 135.122 122.384 1.00 46.87  ? 565 ILE B CG1 1 
ATOM   9392  C  CG2 . ILE D 1 572 ? 104.951 135.333 123.859 1.00 46.87  ? 565 ILE B CG2 1 
ATOM   9393  C  CD1 . ILE D 1 572 ? 106.903 133.616 122.309 1.00 46.87  ? 565 ILE B CD1 1 
ATOM   9394  N  N   . ASP D 1 573 ? 104.940 138.443 125.079 1.00 53.85  ? 566 ASP B N   1 
ATOM   9395  C  CA  . ASP D 1 573 ? 104.370 139.015 126.290 1.00 53.85  ? 566 ASP B CA  1 
ATOM   9396  C  C   . ASP D 1 573 ? 103.367 138.046 126.902 1.00 53.85  ? 566 ASP B C   1 
ATOM   9397  O  O   . ASP D 1 573 ? 102.447 137.584 126.220 1.00 53.85  ? 566 ASP B O   1 
ATOM   9398  C  CB  . ASP D 1 573 ? 103.692 140.351 125.983 1.00 53.85  ? 566 ASP B CB  1 
ATOM   9399  C  CG  . ASP D 1 573 ? 104.678 141.422 125.560 1.00 53.85  ? 566 ASP B CG  1 
ATOM   9400  O  OD1 . ASP D 1 573 ? 105.606 141.720 126.339 1.00 53.85  ? 566 ASP B OD1 1 
ATOM   9401  O  OD2 . ASP D 1 573 ? 104.524 141.967 124.447 1.00 53.85  ? 566 ASP B OD2 1 
ATOM   9402  N  N   . ILE D 1 574 ? 103.576 137.731 128.184 1.00 52.79  ? 567 ILE B N   1 
ATOM   9403  C  CA  . ILE D 1 574 ? 102.617 136.854 128.916 1.00 52.79  ? 567 ILE B CA  1 
ATOM   9404  C  C   . ILE D 1 574 ? 101.887 137.740 129.930 1.00 52.79  ? 567 ILE B C   1 
ATOM   9405  O  O   . ILE D 1 574 ? 102.569 138.375 130.759 1.00 52.79  ? 567 ILE B O   1 
ATOM   9406  C  CB  . ILE D 1 574 ? 103.344 135.668 129.578 1.00 52.79  ? 567 ILE B CB  1 
ATOM   9407  C  CG1 . ILE D 1 574 ? 104.125 134.840 128.553 1.00 52.79  ? 567 ILE B CG1 1 
ATOM   9408  C  CG2 . ILE D 1 574 ? 102.363 134.805 130.357 1.00 52.79  ? 567 ILE B CG2 1 
ATOM   9409  C  CD1 . ILE D 1 574 ? 103.266 134.268 127.452 1.00 52.79  ? 567 ILE B CD1 1 
ATOM   9410  N  N   . PRO D 1 575 ? 100.540 137.819 129.897 1.00 59.52  ? 568 PRO B N   1 
ATOM   9411  C  CA  . PRO D 1 575 ? 99.789  138.723 130.774 1.00 59.52  ? 568 PRO B CA  1 
ATOM   9412  C  C   . PRO D 1 575 ? 100.072 138.462 132.246 1.00 59.52  ? 568 PRO B C   1 
ATOM   9413  O  O   . PRO D 1 575 ? 100.269 137.322 132.671 1.00 59.52  ? 568 PRO B O   1 
ATOM   9414  C  CB  . PRO D 1 575 ? 98.328  138.423 130.420 1.00 59.52  ? 568 PRO B CB  1 
ATOM   9415  C  CG  . PRO D 1 575 ? 98.355  137.095 129.742 1.00 59.52  ? 568 PRO B CG  1 
ATOM   9416  C  CD  . PRO D 1 575 ? 99.659  137.018 129.035 1.00 59.52  ? 568 PRO B CD  1 
ATOM   9417  N  N   . GLN D 1 576 ? 100.095 139.543 133.024 1.00 57.30  ? 569 GLN B N   1 
ATOM   9418  C  CA  . GLN D 1 576 ? 100.327 139.485 134.460 1.00 57.30  ? 569 GLN B CA  1 
ATOM   9419  C  C   . GLN D 1 576 ? 99.864  140.801 135.067 1.00 57.30  ? 569 GLN B C   1 
ATOM   9420  O  O   . GLN D 1 576 ? 99.720  141.800 134.361 1.00 57.30  ? 569 GLN B O   1 
ATOM   9421  C  CB  . GLN D 1 576 ? 101.804 139.230 134.782 1.00 57.30  ? 569 GLN B CB  1 
ATOM   9422  C  CG  . GLN D 1 576 ? 102.062 138.774 136.204 1.00 57.30  ? 569 GLN B CG  1 
ATOM   9423  C  CD  . GLN D 1 576 ? 101.898 137.280 136.370 1.00 57.30  ? 569 GLN B CD  1 
ATOM   9424  O  OE1 . GLN D 1 576 ? 102.604 136.495 135.740 1.00 57.30  ? 569 GLN B OE1 1 
ATOM   9425  N  NE2 . GLN D 1 576 ? 100.962 136.878 137.221 1.00 57.30  ? 569 GLN B NE2 1 
ATOM   9426  N  N   . LEU D 1 577 ? 99.621  140.794 136.374 1.00 57.38  ? 570 LEU B N   1 
ATOM   9427  C  CA  . LEU D 1 577 ? 99.176  141.989 137.077 1.00 57.38  ? 570 LEU B CA  1 
ATOM   9428  C  C   . LEU D 1 577 ? 100.007 142.175 138.336 1.00 57.38  ? 570 LEU B C   1 
ATOM   9429  O  O   . LEU D 1 577 ? 100.235 141.217 139.081 1.00 57.38  ? 570 LEU B O   1 
ATOM   9430  C  CB  . LEU D 1 577 ? 97.690  141.904 137.428 1.00 57.38  ? 570 LEU B CB  1 
ATOM   9431  C  CG  . LEU D 1 577 ? 96.731  142.327 136.315 1.00 57.38  ? 570 LEU B CG  1 
ATOM   9432  C  CD1 . LEU D 1 577 ? 95.324  142.472 136.849 1.00 57.38  ? 570 LEU B CD1 1 
ATOM   9433  C  CD2 . LEU D 1 577 ? 97.192  143.623 135.681 1.00 57.38  ? 570 LEU B CD2 1 
ATOM   9434  N  N   . PHE D 1 578 ? 100.452 143.407 138.570 1.00 52.16  ? 571 PHE B N   1 
ATOM   9435  C  CA  . PHE D 1 578 ? 101.286 143.748 139.712 1.00 52.16  ? 571 PHE B CA  1 
ATOM   9436  C  C   . PHE D 1 578 ? 100.574 144.771 140.586 1.00 52.16  ? 571 PHE B C   1 
ATOM   9437  O  O   . PHE D 1 578 ? 99.810  145.606 140.096 1.00 52.16  ? 571 PHE B O   1 
ATOM   9438  C  CB  . PHE D 1 578 ? 102.641 144.306 139.267 1.00 52.16  ? 571 PHE B CB  1 
ATOM   9439  C  CG  . PHE D 1 578 ? 103.568 143.276 138.687 1.00 52.16  ? 571 PHE B CG  1 
ATOM   9440  C  CD1 . PHE D 1 578 ? 103.288 142.670 137.478 1.00 52.16  ? 571 PHE B CD1 1 
ATOM   9441  C  CD2 . PHE D 1 578 ? 104.730 142.924 139.348 1.00 52.16  ? 571 PHE B CD2 1 
ATOM   9442  C  CE1 . PHE D 1 578 ? 104.141 141.727 136.945 1.00 52.16  ? 571 PHE B CE1 1 
ATOM   9443  C  CE2 . PHE D 1 578 ? 105.587 141.984 138.817 1.00 52.16  ? 571 PHE B CE2 1 
ATOM   9444  C  CZ  . PHE D 1 578 ? 105.291 141.386 137.616 1.00 52.16  ? 571 PHE B CZ  1 
ATOM   9445  N  N   . LYS D 1 579 ? 100.831 144.696 141.889 1.00 56.98  ? 572 LYS B N   1 
ATOM   9446  C  CA  . LYS D 1 579 ? 100.278 145.649 142.842 1.00 56.98  ? 572 LYS B CA  1 
ATOM   9447  C  C   . LYS D 1 579 ? 101.363 146.095 143.807 1.00 56.98  ? 572 LYS B C   1 
ATOM   9448  O  O   . LYS D 1 579 ? 102.253 145.316 144.154 1.00 56.98  ? 572 LYS B O   1 
ATOM   9449  C  CB  . LYS D 1 579 ? 99.089  145.049 143.603 1.00 56.98  ? 572 LYS B CB  1 
ATOM   9450  C  CG  . LYS D 1 579 ? 99.335  143.666 144.185 1.00 56.98  ? 572 LYS B CG  1 
ATOM   9451  C  CD  . LYS D 1 579 ? 99.795  143.704 145.634 1.00 56.98  ? 572 LYS B CD  1 
ATOM   9452  C  CE  . LYS D 1 579 ? 99.744  142.310 146.242 1.00 56.98  ? 572 LYS B CE  1 
ATOM   9453  N  NZ  . LYS D 1 579 ? 100.329 142.252 147.608 1.00 56.98  ? 572 LYS B NZ  1 
ATOM   9454  N  N   . LEU D 1 580 ? 101.283 147.349 144.240 1.00 59.38  ? 573 LEU B N   1 
ATOM   9455  C  CA  . LEU D 1 580 ? 102.310 147.954 145.074 1.00 59.38  ? 573 LEU B CA  1 
ATOM   9456  C  C   . LEU D 1 580 ? 101.927 147.889 146.548 1.00 59.38  ? 573 LEU B C   1 
ATOM   9457  O  O   . LEU D 1 580 ? 100.756 148.007 146.917 1.00 59.38  ? 573 LEU B O   1 
ATOM   9458  C  CB  . LEU D 1 580 ? 102.564 149.406 144.665 1.00 59.38  ? 573 LEU B CB  1 
ATOM   9459  C  CG  . LEU D 1 580 ? 102.970 149.633 143.207 1.00 59.38  ? 573 LEU B CG  1 
ATOM   9460  C  CD1 . LEU D 1 580 ? 103.220 151.103 142.947 1.00 59.38  ? 573 LEU B CD1 1 
ATOM   9461  C  CD2 . LEU D 1 580 ? 104.195 148.814 142.851 1.00 59.38  ? 573 LEU B CD2 1 
ATOM   9462  N  N   . LYS D 1 581 ? 102.946 147.740 147.381 1.00 64.01  ? 574 LYS B N   1 
ATOM   9463  C  CA  . LYS D 1 581 ? 102.662 147.678 148.828 1.00 64.01  ? 574 LYS B CA  1 
ATOM   9464  C  C   . LYS D 1 581 ? 103.617 148.609 149.566 1.00 64.01  ? 574 LYS B C   1 
ATOM   9465  O  O   . LYS D 1 581 ? 104.115 149.566 148.946 1.00 64.01  ? 574 LYS B O   1 
ATOM   9466  C  CB  . LYS D 1 581 ? 102.809 146.234 149.320 1.00 64.01  ? 574 LYS B CB  1 
ATOM   9467  C  CG  . LYS D 1 581 ? 101.877 145.835 150.456 1.00 64.01  ? 574 LYS B CG  1 
ATOM   9468  C  CD  . LYS D 1 581 ? 100.416 146.037 150.121 1.00 64.01  ? 574 LYS B CD  1 
ATOM   9469  C  CE  . LYS D 1 581 ? 99.497  145.739 151.286 1.00 64.01  ? 574 LYS B CE  1 
ATOM   9470  N  NZ  . LYS D 1 581 ? 99.812  146.586 152.460 1.00 64.01  ? 574 LYS B NZ  1 
ATOM   9471  N  N   . GLU D 1 582 ? 103.898 148.239 150.822 1.00 69.86  ? 575 GLU B N   1 
ATOM   9472  C  CA  . GLU D 1 582 ? 104.824 149.020 151.676 1.00 69.86  ? 575 GLU B CA  1 
ATOM   9473  C  C   . GLU D 1 582 ? 106.050 149.429 150.869 1.00 69.86  ? 575 GLU B C   1 
ATOM   9474  O  O   . GLU D 1 582 ? 106.593 148.586 150.126 1.00 69.86  ? 575 GLU B O   1 
ATOM   9475  C  CB  . GLU D 1 582 ? 105.235 148.191 152.894 1.00 69.86  ? 575 GLU B CB  1 
ATOM   9476  C  CG  . GLU D 1 582 ? 104.053 147.667 153.688 1.00 69.86  ? 575 GLU B CG  1 
ATOM   9477  C  CD  . GLU D 1 582 ? 104.425 146.814 154.889 1.00 69.86  ? 575 GLU B CD  1 
ATOM   9478  O  OE1 . GLU D 1 582 ? 105.636 146.624 155.124 1.00 69.86  ? 575 GLU B OE1 1 
ATOM   9479  O  OE2 . GLU D 1 582 ? 103.506 146.342 155.584 1.00 69.86  ? 575 GLU B OE2 1 
ATOM   9480  N  N   . PHE D 1 583 ? 106.467 150.676 151.041 1.00 69.03  ? 576 PHE B N   1 
ATOM   9481  C  CA  . PHE D 1 583 ? 107.627 151.217 150.324 1.00 69.03  ? 576 PHE B CA  1 
ATOM   9482  C  C   . PHE D 1 583 ? 107.519 151.072 148.809 1.00 69.03  ? 576 PHE B C   1 
ATOM   9483  O  O   . PHE D 1 583 ? 108.536 151.121 148.109 1.00 69.03  ? 576 PHE B O   1 
ATOM   9484  C  CB  . PHE D 1 583 ? 108.951 150.619 150.822 1.00 69.03  ? 576 PHE B CB  1 
ATOM   9485  C  CG  . PHE D 1 583 ? 109.290 150.967 152.252 1.00 69.03  ? 576 PHE B CG  1 
ATOM   9486  C  CD1 . PHE D 1 583 ? 110.581 150.790 152.722 1.00 69.03  ? 576 PHE B CD1 1 
ATOM   9487  C  CD2 . PHE D 1 583 ? 108.355 151.548 153.096 1.00 69.03  ? 576 PHE B CD2 1 
ATOM   9488  C  CE1 . PHE D 1 583 ? 110.916 151.123 154.022 1.00 69.03  ? 576 PHE B CE1 1 
ATOM   9489  C  CE2 . PHE D 1 583 ? 108.684 151.885 154.399 1.00 69.03  ? 576 PHE B CE2 1 
ATOM   9490  C  CZ  . PHE D 1 583 ? 109.969 151.674 154.860 1.00 69.03  ? 576 PHE B CZ  1 
ATOM   9491  N  N   . SER D 1 584 ? 106.301 150.911 148.292 1.00 62.82  ? 577 SER B N   1 
ATOM   9492  C  CA  . SER D 1 584 ? 106.029 150.958 146.853 1.00 62.82  ? 577 SER B CA  1 
ATOM   9493  C  C   . SER D 1 584 ? 106.869 149.941 146.083 1.00 62.82  ? 577 SER B C   1 
ATOM   9494  O  O   . SER D 1 584 ? 107.681 150.290 145.225 1.00 62.82  ? 577 SER B O   1 
ATOM   9495  C  CB  . SER D 1 584 ? 106.244 152.371 146.306 1.00 62.82  ? 577 SER B CB  1 
ATOM   9496  O  OG  . SER D 1 584 ? 105.256 153.262 146.791 1.00 62.82  ? 577 SER B OG  1 
ATOM   9497  N  N   . LYS D 1 585 ? 106.664 148.667 146.397 1.00 56.83  ? 578 LYS B N   1 
ATOM   9498  C  CA  . LYS D 1 585 ? 107.303 147.567 145.691 1.00 56.83  ? 578 LYS B CA  1 
ATOM   9499  C  C   . LYS D 1 585 ? 106.240 146.659 145.085 1.00 56.83  ? 578 LYS B C   1 
ATOM   9500  O  O   . LYS D 1 585 ? 105.145 146.505 145.633 1.00 56.83  ? 578 LYS B O   1 
ATOM   9501  C  CB  . LYS D 1 585 ? 108.210 146.762 146.623 1.00 56.83  ? 578 LYS B CB  1 
ATOM   9502  C  CG  . LYS D 1 585 ? 109.248 147.588 147.360 1.00 56.83  ? 578 LYS B CG  1 
ATOM   9503  C  CD  . LYS D 1 585 ? 110.121 148.372 146.400 1.00 56.83  ? 578 LYS B CD  1 
ATOM   9504  C  CE  . LYS D 1 585 ? 111.181 149.160 147.147 1.00 56.83  ? 578 LYS B CE  1 
ATOM   9505  N  NZ  . LYS D 1 585 ? 112.090 149.891 146.225 1.00 56.83  ? 578 LYS B NZ  1 
ATOM   9506  N  N   . ALA D 1 586 ? 106.577 146.054 143.953 1.00 53.56  ? 579 ALA B N   1 
ATOM   9507  C  CA  . ALA D 1 586 ? 105.612 145.300 143.169 1.00 53.56  ? 579 ALA B CA  1 
ATOM   9508  C  C   . ALA D 1 586 ? 105.534 143.852 143.632 1.00 53.56  ? 579 ALA B C   1 
ATOM   9509  O  O   . ALA D 1 586 ? 106.554 143.215 143.905 1.00 53.56  ? 579 ALA B O   1 
ATOM   9510  C  CB  . ALA D 1 586 ? 105.975 145.348 141.685 1.00 53.56  ? 579 ALA B CB  1 
ATOM   9511  N  N   . GLU D 1 587 ? 104.308 143.340 143.713 1.00 60.02  ? 580 GLU B N   1 
ATOM   9512  C  CA  . GLU D 1 587 ? 104.048 141.936 143.983 1.00 60.02  ? 580 GLU B CA  1 
ATOM   9513  C  C   . GLU D 1 587 ? 103.042 141.432 142.961 1.00 60.02  ? 580 GLU B C   1 
ATOM   9514  O  O   . GLU D 1 587 ? 102.224 142.193 142.438 1.00 60.02  ? 580 GLU B O   1 
ATOM   9515  C  CB  . GLU D 1 587 ? 103.507 141.710 145.401 1.00 60.02  ? 580 GLU B CB  1 
ATOM   9516  C  CG  . GLU D 1 587 ? 104.559 141.725 146.492 1.00 60.02  ? 580 GLU B CG  1 
ATOM   9517  C  CD  . GLU D 1 587 ? 103.946 141.775 147.878 1.00 60.02  ? 580 GLU B CD  1 
ATOM   9518  O  OE1 . GLU D 1 587 ? 102.741 141.472 148.007 1.00 60.02  ? 580 GLU B OE1 1 
ATOM   9519  O  OE2 . GLU D 1 587 ? 104.666 142.123 148.837 1.00 60.02  ? 580 GLU B OE2 1 
ATOM   9520  N  N   . ALA D 1 588 ? 103.104 140.134 142.682 1.00 58.60  ? 581 ALA B N   1 
ATOM   9521  C  CA  . ALA D 1 588 ? 102.195 139.539 141.712 1.00 58.60  ? 581 ALA B CA  1 
ATOM   9522  C  C   . ALA D 1 588 ? 100.771 139.546 142.253 1.00 58.60  ? 581 ALA B C   1 
ATOM   9523  O  O   . ALA D 1 588 ? 100.506 139.027 143.340 1.00 58.60  ? 581 ALA B O   1 
ATOM   9524  C  CB  . ALA D 1 588 ? 102.632 138.114 141.385 1.00 58.60  ? 581 ALA B CB  1 
ATOM   9525  N  N   . PHE D 1 589 ? 99.851  140.142 141.491 1.00 65.18  ? 582 PHE B N   1 
ATOM   9526  C  CA  . PHE D 1 589 ? 98.458  140.193 141.921 1.00 65.18  ? 582 PHE B CA  1 
ATOM   9527  C  C   . PHE D 1 589 ? 97.847  138.798 141.957 1.00 65.18  ? 582 PHE B C   1 
ATOM   9528  O  O   . PHE D 1 589 ? 97.175  138.426 142.925 1.00 65.18  ? 582 PHE B O   1 
ATOM   9529  C  CB  . PHE D 1 589 ? 97.658  141.115 141.003 1.00 65.18  ? 582 PHE B CB  1 
ATOM   9530  C  CG  . PHE D 1 589 ? 96.246  141.338 141.453 1.00 65.18  ? 582 PHE B CG  1 
ATOM   9531  C  CD1 . PHE D 1 589 ? 95.979  142.008 142.633 1.00 65.18  ? 582 PHE B CD1 1 
ATOM   9532  C  CD2 . PHE D 1 589 ? 95.183  140.879 140.693 1.00 65.18  ? 582 PHE B CD2 1 
ATOM   9533  C  CE1 . PHE D 1 589 ? 94.681  142.214 143.050 1.00 65.18  ? 582 PHE B CE1 1 
ATOM   9534  C  CE2 . PHE D 1 589 ? 93.883  141.083 141.104 1.00 65.18  ? 582 PHE B CE2 1 
ATOM   9535  C  CZ  . PHE D 1 589 ? 93.631  141.752 142.283 1.00 65.18  ? 582 PHE B CZ  1 
ATOM   9536  N  N   . PHE D 1 590 ? 98.137  138.015 140.911 1.00 63.76  ? 583 PHE B N   1 
ATOM   9537  C  CA  . PHE D 1 590 ? 97.713  136.591 140.875 1.00 63.76  ? 583 PHE B CA  1 
ATOM   9538  C  C   . PHE D 1 590 ? 98.983  135.782 140.578 1.00 63.76  ? 583 PHE B C   1 
ATOM   9539  O  O   . PHE D 1 590 ? 99.968  136.402 140.133 1.00 63.76  ? 583 PHE B O   1 
ATOM   9540  C  CB  . PHE D 1 590 ? 96.565  136.393 139.879 1.00 63.76  ? 583 PHE B CB  1 
ATOM   9541  C  CG  . PHE D 1 590 ? 96.783  136.950 138.496 1.00 63.76  ? 583 PHE B CG  1 
ATOM   9542  C  CD1 . PHE D 1 590 ? 97.755  136.429 137.657 1.00 63.76  ? 583 PHE B CD1 1 
ATOM   9543  C  CD2 . PHE D 1 590 ? 96.006  137.998 138.028 1.00 63.76  ? 583 PHE B CD2 1 
ATOM   9544  C  CE1 . PHE D 1 590 ? 97.944  136.942 136.385 1.00 63.76  ? 583 PHE B CE1 1 
ATOM   9545  C  CE2 . PHE D 1 590 ? 96.197  138.512 136.755 1.00 63.76  ? 583 PHE B CE2 1 
ATOM   9546  C  CZ  . PHE D 1 590 ? 97.168  137.984 135.937 1.00 63.76  ? 583 PHE B CZ  1 
ATOM   9547  N  N   . PRO D 1 591 ? 99.034  134.448 140.790 1.00 65.60  ? 584 PRO B N   1 
ATOM   9548  C  CA  . PRO D 1 591 ? 100.281 133.686 140.620 1.00 65.60  ? 584 PRO B CA  1 
ATOM   9549  C  C   . PRO D 1 591 ? 101.100 134.096 139.386 1.00 65.60  ? 584 PRO B C   1 
ATOM   9550  O  O   . PRO D 1 591 ? 100.529 134.201 138.317 1.00 65.60  ? 584 PRO B O   1 
ATOM   9551  C  CB  . PRO D 1 591 ? 99.760  132.254 140.451 1.00 65.60  ? 584 PRO B CB  1 
ATOM   9552  C  CG  . PRO D 1 591 ? 98.530  132.217 141.328 1.00 65.60  ? 584 PRO B CG  1 
ATOM   9553  C  CD  . PRO D 1 591 ? 97.914  133.596 141.201 1.00 65.60  ? 584 PRO B CD  1 
ATOM   9554  N  N   . ASN D 1 592 ? 102.410 134.309 139.561 1.00 59.62  ? 585 ASN B N   1 
ATOM   9555  C  CA  . ASN D 1 592 ? 103.290 134.733 138.437 1.00 59.62  ? 585 ASN B CA  1 
ATOM   9556  C  C   . ASN D 1 592 ? 103.468 133.572 137.458 1.00 59.62  ? 585 ASN B C   1 
ATOM   9557  O  O   . ASN D 1 592 ? 104.045 132.549 137.865 1.00 59.62  ? 585 ASN B O   1 
ATOM   9558  C  CB  . ASN D 1 592 ? 104.647 135.247 138.920 1.00 59.62  ? 585 ASN B CB  1 
ATOM   9559  C  CG  . ASN D 1 592 ? 105.548 135.683 137.784 1.00 59.62  ? 585 ASN B CG  1 
ATOM   9560  O  OD1 . ASN D 1 592 ? 106.632 135.134 137.600 1.00 59.62  ? 585 ASN B OD1 1 
ATOM   9561  N  ND2 . ASN D 1 592 ? 105.108 136.665 137.017 1.00 59.62  ? 585 ASN B ND2 1 
ATOM   9562  N  N   . MET D 1 593 ? 103.008 133.737 136.216 1.00 57.97  ? 586 MET B N   1 
ATOM   9563  C  CA  . MET D 1 593 ? 103.105 132.688 135.212 1.00 57.97  ? 586 MET B CA  1 
ATOM   9564  C  C   . MET D 1 593 ? 104.355 132.801 134.356 1.00 57.97  ? 586 MET B C   1 
ATOM   9565  O  O   . MET D 1 593 ? 104.548 131.984 133.452 1.00 57.97  ? 586 MET B O   1 
ATOM   9566  C  CB  . MET D 1 593 ? 101.870 132.700 134.312 1.00 57.97  ? 586 MET B CB  1 
ATOM   9567  C  CG  . MET D 1 593 ? 100.580 132.977 135.051 1.00 57.97  ? 586 MET B CG  1 
ATOM   9568  S  SD  . MET D 1 593 ? 99.157  132.935 133.956 1.00 57.97  ? 586 MET B SD  1 
ATOM   9569  C  CE  . MET D 1 593 ? 99.836  131.996 132.599 1.00 57.97  ? 586 MET B CE  1 
ATOM   9570  N  N   . VAL D 1 594 ? 105.209 133.789 134.642 1.00 55.29  ? 587 VAL B N   1 
ATOM   9571  C  CA  . VAL D 1 594 ? 106.502 133.908 133.904 1.00 55.29  ? 587 VAL B CA  1 
ATOM   9572  C  C   . VAL D 1 594 ? 107.515 132.986 134.589 1.00 55.29  ? 587 VAL B C   1 
ATOM   9573  O  O   . VAL D 1 594 ? 108.342 132.389 133.881 1.00 55.29  ? 587 VAL B O   1 
ATOM   9574  C  CB  . VAL D 1 594 ? 106.989 135.369 133.865 1.00 55.29  ? 587 VAL B CB  1 
ATOM   9575  C  CG1 . VAL D 1 594 ? 108.363 135.498 133.227 1.00 55.29  ? 587 VAL B CG1 1 
ATOM   9576  C  CG2 . VAL D 1 594 ? 105.987 136.260 133.150 1.00 55.29  ? 587 VAL B CG2 1 
ATOM   9577  N  N   . ASN D 1 595 ? 107.435 132.869 135.915 1.00 58.35  ? 588 ASN B N   1 
ATOM   9578  C  CA  . ASN D 1 595 ? 108.328 131.999 136.677 1.00 58.35  ? 588 ASN B CA  1 
ATOM   9579  C  C   . ASN D 1 595 ? 107.819 130.565 136.561 1.00 58.35  ? 588 ASN B C   1 
ATOM   9580  O  O   . ASN D 1 595 ? 107.175 130.020 137.460 1.00 58.35  ? 588 ASN B O   1 
ATOM   9581  C  CB  . ASN D 1 595 ? 108.403 132.453 138.128 1.00 58.35  ? 588 ASN B CB  1 
ATOM   9582  C  CG  . ASN D 1 595 ? 109.715 132.087 138.786 1.00 58.35  ? 588 ASN B CG  1 
ATOM   9583  O  OD1 . ASN D 1 595 ? 110.703 131.802 138.110 1.00 58.35  ? 588 ASN B OD1 1 
ATOM   9584  N  ND2 . ASN D 1 595 ? 109.732 132.092 140.113 1.00 58.35  ? 588 ASN B ND2 1 
ATOM   9585  N  N   . MET D 1 596 ? 108.126 129.976 135.404 1.00 56.40  ? 589 MET B N   1 
ATOM   9586  C  CA  . MET D 1 596 ? 107.670 128.590 135.146 1.00 56.40  ? 589 MET B CA  1 
ATOM   9587  C  C   . MET D 1 596 ? 108.884 127.672 135.005 1.00 56.40  ? 589 MET B C   1 
ATOM   9588  O  O   . MET D 1 596 ? 109.999 128.190 134.799 1.00 56.40  ? 589 MET B O   1 
ATOM   9589  C  CB  . MET D 1 596 ? 106.833 128.521 133.864 1.00 56.40  ? 589 MET B CB  1 
ATOM   9590  C  CG  . MET D 1 596 ? 107.230 129.554 132.829 1.00 56.40  ? 589 MET B CG  1 
ATOM   9591  S  SD  . MET D 1 596 ? 106.194 129.495 131.345 1.00 56.40  ? 589 MET B SD  1 
ATOM   9592  C  CE  . MET D 1 596 ? 107.344 130.120 130.120 1.00 56.40  ? 589 MET B CE  1 
ATOM   9593  N  N   . LEU D 1 597 ? 108.663 126.369 135.112 1.00 54.34  ? 590 LEU B N   1 
ATOM   9594  C  CA  . LEU D 1 597 ? 109.702 125.357 135.003 1.00 54.34  ? 590 LEU B CA  1 
ATOM   9595  C  C   . LEU D 1 597 ? 109.721 124.806 133.586 1.00 54.34  ? 590 LEU B C   1 
ATOM   9596  O  O   . LEU D 1 597 ? 108.716 124.268 133.114 1.00 54.34  ? 590 LEU B O   1 
ATOM   9597  C  CB  . LEU D 1 597 ? 109.464 124.229 136.005 1.00 54.34  ? 590 LEU B CB  1 
ATOM   9598  C  CG  . LEU D 1 597 ? 110.523 123.131 136.046 1.00 54.34  ? 590 LEU B CG  1 
ATOM   9599  C  CD1 . LEU D 1 597 ? 111.784 123.660 136.691 1.00 54.34  ? 590 LEU B CD1 1 
ATOM   9600  C  CD2 . LEU D 1 597 ? 110.003 121.914 136.791 1.00 54.34  ? 590 LEU B CD2 1 
ATOM   9601  N  N   . VAL D 1 598 ? 110.859 124.934 132.911 1.00 51.26  ? 591 VAL B N   1 
ATOM   9602  C  CA  . VAL D 1 598 ? 111.011 124.472 131.535 1.00 51.26  ? 591 VAL B CA  1 
ATOM   9603  C  C   . VAL D 1 598 ? 111.912 123.243 131.533 1.00 51.26  ? 591 VAL B C   1 
ATOM   9604  O  O   . VAL D 1 598 ? 113.026 123.270 132.072 1.00 51.26  ? 591 VAL B O   1 
ATOM   9605  C  CB  . VAL D 1 598 ? 111.542 125.589 130.618 1.00 51.26  ? 591 VAL B CB  1 
ATOM   9606  C  CG1 . VAL D 1 598 ? 112.939 126.032 131.017 1.00 51.26  ? 591 VAL B CG1 1 
ATOM   9607  C  CG2 . VAL D 1 598 ? 111.535 125.127 129.172 1.00 51.26  ? 591 VAL B CG2 1 
ATOM   9608  N  N   . LEU D 1 599 ? 111.412 122.149 130.958 1.00 51.87  ? 592 LEU B N   1 
ATOM   9609  C  CA  . LEU D 1 599 ? 112.134 120.882 130.872 1.00 51.87  ? 592 LEU B CA  1 
ATOM   9610  C  C   . LEU D 1 599 ? 112.053 120.437 129.416 1.00 51.87  ? 592 LEU B C   1 
ATOM   9611  O  O   . LEU D 1 599 ? 111.088 119.782 129.013 1.00 51.87  ? 592 LEU B O   1 
ATOM   9612  C  CB  . LEU D 1 599 ? 111.543 119.838 131.818 1.00 51.87  ? 592 LEU B CB  1 
ATOM   9613  C  CG  . LEU D 1 599 ? 111.648 120.069 133.326 1.00 51.87  ? 592 LEU B CG  1 
ATOM   9614  C  CD1 . LEU D 1 599 ? 110.998 118.921 134.073 1.00 51.87  ? 592 LEU B CD1 1 
ATOM   9615  C  CD2 . LEU D 1 599 ? 113.093 120.220 133.753 1.00 51.87  ? 592 LEU B CD2 1 
ATOM   9616  N  N   . GLY D 1 600 ? 113.061 120.801 128.629 1.00 56.11  ? 593 GLY B N   1 
ATOM   9617  C  CA  . GLY D 1 600 ? 113.055 120.474 127.218 1.00 56.11  ? 593 GLY B CA  1 
ATOM   9618  C  C   . GLY D 1 600 ? 111.896 121.124 126.492 1.00 56.11  ? 593 GLY B C   1 
ATOM   9619  O  O   . GLY D 1 600 ? 111.882 122.340 126.291 1.00 56.11  ? 593 GLY B O   1 
ATOM   9620  N  N   . LYS D 1 601 ? 110.914 120.319 126.096 1.00 62.14  ? 594 LYS B N   1 
ATOM   9621  C  CA  . LYS D 1 601 ? 109.712 120.815 125.442 1.00 62.14  ? 594 LYS B CA  1 
ATOM   9622  C  C   . LYS D 1 601 ? 108.482 120.719 126.334 1.00 62.14  ? 594 LYS B C   1 
ATOM   9623  O  O   . LYS D 1 601 ? 107.357 120.734 125.826 1.00 62.14  ? 594 LYS B O   1 
ATOM   9624  C  CB  . LYS D 1 601 ? 109.473 120.061 124.132 1.00 62.14  ? 594 LYS B CB  1 
ATOM   9625  C  CG  . LYS D 1 601 ? 110.737 119.784 123.339 1.00 62.14  ? 594 LYS B CG  1 
ATOM   9626  C  CD  . LYS D 1 601 ? 110.491 118.753 122.251 1.00 62.14  ? 594 LYS B CD  1 
ATOM   9627  C  CE  . LYS D 1 601 ? 111.461 118.929 121.095 1.00 62.14  ? 594 LYS B CE  1 
ATOM   9628  N  NZ  . LYS D 1 601 ? 111.597 120.359 120.702 1.00 62.14  ? 594 LYS B NZ  1 
ATOM   9629  N  N   . HIS D 1 602 ? 108.665 120.622 127.648 1.00 64.45  ? 595 HIS B N   1 
ATOM   9630  C  CA  . HIS D 1 602 ? 107.562 120.503 128.590 1.00 64.45  ? 595 HIS B CA  1 
ATOM   9631  C  C   . HIS D 1 602 ? 107.601 121.666 129.571 1.00 64.45  ? 595 HIS B C   1 
ATOM   9632  O  O   . HIS D 1 602 ? 108.679 122.138 129.951 1.00 64.45  ? 595 HIS B O   1 
ATOM   9633  C  CB  . HIS D 1 602 ? 107.623 119.167 129.336 1.00 64.45  ? 595 HIS B CB  1 
ATOM   9634  C  CG  . HIS D 1 602 ? 107.575 117.975 128.433 1.00 64.45  ? 595 HIS B CG  1 
ATOM   9635  N  ND1 . HIS D 1 602 ? 106.483 117.681 127.645 1.00 64.45  ? 595 HIS B ND1 1 
ATOM   9636  C  CD2 . HIS D 1 602 ? 108.487 117.005 128.186 1.00 64.45  ? 595 HIS B CD2 1 
ATOM   9637  C  CE1 . HIS D 1 602 ? 106.723 116.582 126.954 1.00 64.45  ? 595 HIS B CE1 1 
ATOM   9638  N  NE2 . HIS D 1 602 ? 107.932 116.151 127.265 1.00 64.45  ? 595 HIS B NE2 1 
ATOM   9639  N  N   . LEU D 1 603 ? 106.423 122.133 129.976 1.00 64.41  ? 596 LEU B N   1 
ATOM   9640  C  CA  . LEU D 1 603 ? 106.304 123.337 130.784 1.00 64.41  ? 596 LEU B CA  1 
ATOM   9641  C  C   . LEU D 1 603 ? 105.450 123.067 132.014 1.00 64.41  ? 596 LEU B C   1 
ATOM   9642  O  O   . LEU D 1 603 ? 104.351 122.514 131.903 1.00 64.41  ? 596 LEU B O   1 
ATOM   9643  C  CB  . LEU D 1 603 ? 105.690 124.480 129.972 1.00 64.41  ? 596 LEU B CB  1 
ATOM   9644  C  CG  . LEU D 1 603 ? 106.513 125.033 128.811 1.00 64.41  ? 596 LEU B CG  1 
ATOM   9645  C  CD1 . LEU D 1 603 ? 105.915 126.337 128.325 1.00 64.41  ? 596 LEU B CD1 1 
ATOM   9646  C  CD2 . LEU D 1 603 ? 107.953 125.235 129.228 1.00 64.41  ? 596 LEU B CD2 1 
ATOM   9647  N  N   . GLY D 1 604 ? 105.963 123.454 133.178 1.00 63.24  ? 597 GLY B N   1 
ATOM   9648  C  CA  . GLY D 1 604 ? 105.163 123.545 134.381 1.00 63.24  ? 597 GLY B CA  1 
ATOM   9649  C  C   . GLY D 1 604 ? 104.927 125.000 134.731 1.00 63.24  ? 597 GLY B C   1 
ATOM   9650  O  O   . GLY D 1 604 ? 105.834 125.683 135.215 1.00 63.24  ? 597 GLY B O   1 
ATOM   9651  N  N   . ILE D 1 605 ? 103.720 125.484 134.483 1.00 63.69  ? 598 ILE B N   1 
ATOM   9652  C  CA  . ILE D 1 605 ? 103.367 126.893 134.644 1.00 63.69  ? 598 ILE B CA  1 
ATOM   9653  C  C   . ILE D 1 605 ? 102.484 127.023 135.877 1.00 63.69  ? 598 ILE B C   1 
ATOM   9654  O  O   . ILE D 1 605 ? 101.535 126.246 136.025 1.00 63.69  ? 598 ILE B O   1 
ATOM   9655  C  CB  . ILE D 1 605 ? 102.644 127.443 133.402 1.00 63.69  ? 598 ILE B CB  1 
ATOM   9656  C  CG1 . ILE D 1 605 ? 103.451 127.144 132.140 1.00 63.69  ? 598 ILE B CG1 1 
ATOM   9657  C  CG2 . ILE D 1 605 ? 102.403 128.931 133.540 1.00 63.69  ? 598 ILE B CG2 1 
ATOM   9658  C  CD1 . ILE D 1 605 ? 102.747 127.528 130.866 1.00 63.69  ? 598 ILE B CD1 1 
ATOM   9659  N  N   . PRO D 1 606 ? 102.761 127.960 136.781 1.00 60.25  ? 599 PRO B N   1 
ATOM   9660  C  CA  . PRO D 1 606 ? 101.876 128.149 137.935 1.00 60.25  ? 599 PRO B CA  1 
ATOM   9661  C  C   . PRO D 1 606 ? 100.463 128.491 137.492 1.00 60.25  ? 599 PRO B C   1 
ATOM   9662  O  O   . PRO D 1 606 ? 100.255 129.286 136.575 1.00 60.25  ? 599 PRO B O   1 
ATOM   9663  C  CB  . PRO D 1 606 ? 102.525 129.311 138.692 1.00 60.25  ? 599 PRO B CB  1 
ATOM   9664  C  CG  . PRO D 1 606 ? 103.945 129.283 138.273 1.00 60.25  ? 599 PRO B CG  1 
ATOM   9665  C  CD  . PRO D 1 606 ? 103.943 128.832 136.846 1.00 60.25  ? 599 PRO B CD  1 
ATOM   9666  N  N   . LYS D 1 607 ? 99.489  127.885 138.159 1.00 73.34  ? 600 LYS B N   1 
ATOM   9667  C  CA  . LYS D 1 607 ? 98.096  128.074 137.780 1.00 73.34  ? 600 LYS B CA  1 
ATOM   9668  C  C   . LYS D 1 607 ? 97.618  129.443 138.246 1.00 73.34  ? 600 LYS B C   1 
ATOM   9669  O  O   . LYS D 1 607 ? 97.646  129.721 139.449 1.00 73.34  ? 600 LYS B O   1 
ATOM   9670  C  CB  . LYS D 1 607 ? 97.226  126.978 138.380 1.00 73.34  ? 600 LYS B CB  1 
ATOM   9671  C  CG  . LYS D 1 607 ? 95.923  126.753 137.636 1.00 73.34  ? 600 LYS B CG  1 
ATOM   9672  C  CD  . LYS D 1 607 ? 95.261  125.452 138.051 1.00 73.34  ? 600 LYS B CD  1 
ATOM   9673  C  CE  . LYS D 1 607 ? 93.977  125.222 137.276 1.00 73.34  ? 600 LYS B CE  1 
ATOM   9674  N  NZ  . LYS D 1 607 ? 92.938  126.229 137.621 1.00 73.34  ? 600 LYS B NZ  1 
ATOM   9675  N  N   . PRO D 1 608 ? 97.167  130.317 137.342 1.00 72.35  ? 601 PRO B N   1 
ATOM   9676  C  CA  . PRO D 1 608 ? 96.750  131.659 137.768 1.00 72.35  ? 601 PRO B CA  1 
ATOM   9677  C  C   . PRO D 1 608 ? 95.402  131.690 138.451 1.00 72.35  ? 601 PRO B C   1 
ATOM   9678  O  O   . PRO D 1 608 ? 95.109  132.670 139.148 1.00 72.35  ? 601 PRO B O   1 
ATOM   9679  C  CB  . PRO D 1 608 ? 96.713  132.440 136.452 1.00 72.35  ? 601 PRO B CB  1 
ATOM   9680  C  CG  . PRO D 1 608 ? 96.333  131.405 135.451 1.00 72.35  ? 601 PRO B CG  1 
ATOM   9681  C  CD  . PRO D 1 608 ? 97.008  130.128 135.892 1.00 72.35  ? 601 PRO B CD  1 
ATOM   9682  N  N   . PHE D 1 609 ? 94.577  130.658 138.277 1.00 86.50  ? 602 PHE B N   1 
ATOM   9683  C  CA  . PHE D 1 609 ? 93.194  130.662 138.754 1.00 86.50  ? 602 PHE B CA  1 
ATOM   9684  C  C   . PHE D 1 609 ? 92.433  131.863 138.200 1.00 86.50  ? 602 PHE B C   1 
ATOM   9685  O  O   . PHE D 1 609 ? 91.652  132.513 138.899 1.00 86.50  ? 602 PHE B O   1 
ATOM   9686  C  CB  . PHE D 1 609 ? 93.132  130.626 140.281 1.00 86.50  ? 602 PHE B CB  1 
ATOM   9687  C  CG  . PHE D 1 609 ? 93.495  129.295 140.867 1.00 86.50  ? 602 PHE B CG  1 
ATOM   9688  C  CD1 . PHE D 1 609 ? 92.734  128.173 140.593 1.00 86.50  ? 602 PHE B CD1 1 
ATOM   9689  C  CD2 . PHE D 1 609 ? 94.601  129.166 141.689 1.00 86.50  ? 602 PHE B CD2 1 
ATOM   9690  C  CE1 . PHE D 1 609 ? 93.067  126.945 141.128 1.00 86.50  ? 602 PHE B CE1 1 
ATOM   9691  C  CE2 . PHE D 1 609 ? 94.939  127.941 142.229 1.00 86.50  ? 602 PHE B CE2 1 
ATOM   9692  C  CZ  . PHE D 1 609 ? 94.172  126.829 141.948 1.00 86.50  ? 602 PHE B CZ  1 
ATOM   9693  N  N   . GLY D 1 610 ? 92.668  132.164 136.923 1.00 90.15  ? 603 GLY B N   1 
ATOM   9694  C  CA  . GLY D 1 610 ? 92.004  133.266 136.273 1.00 90.15  ? 603 GLY B CA  1 
ATOM   9695  C  C   . GLY D 1 610 ? 90.553  132.962 135.982 1.00 90.15  ? 603 GLY B C   1 
ATOM   9696  O  O   . GLY D 1 610 ? 90.077  131.826 136.111 1.00 90.15  ? 603 GLY B O   1 
ATOM   9697  N  N   . PRO D 1 611 ? 89.819  134.000 135.581 1.00 91.37  ? 604 PRO B N   1 
ATOM   9698  C  CA  . PRO D 1 611 ? 88.388  133.831 135.307 1.00 91.37  ? 604 PRO B CA  1 
ATOM   9699  C  C   . PRO D 1 611 ? 88.151  132.829 134.189 1.00 91.37  ? 604 PRO B C   1 
ATOM   9700  O  O   . PRO D 1 611 ? 88.909  132.754 133.220 1.00 91.37  ? 604 PRO B O   1 
ATOM   9701  C  CB  . PRO D 1 611 ? 87.934  135.238 134.903 1.00 91.37  ? 604 PRO B CB  1 
ATOM   9702  C  CG  . PRO D 1 611 ? 88.989  136.152 135.438 1.00 91.37  ? 604 PRO B CG  1 
ATOM   9703  C  CD  . PRO D 1 611 ? 90.265  135.382 135.349 1.00 91.37  ? 604 PRO B CD  1 
ATOM   9704  N  N   . VAL D 1 612 ? 87.079  132.054 134.332 1.00 95.02  ? 605 VAL B N   1 
ATOM   9705  C  CA  . VAL D 1 612 ? 86.760  130.969 133.412 1.00 95.02  ? 605 VAL B CA  1 
ATOM   9706  C  C   . VAL D 1 612 ? 85.571  131.377 132.554 1.00 95.02  ? 605 VAL B C   1 
ATOM   9707  O  O   . VAL D 1 612 ? 84.651  132.056 133.026 1.00 95.02  ? 605 VAL B O   1 
ATOM   9708  C  CB  . VAL D 1 612 ? 86.490  129.650 134.162 1.00 95.02  ? 605 VAL B CB  1 
ATOM   9709  C  CG1 . VAL D 1 612 ? 87.583  129.394 135.187 1.00 95.02  ? 605 VAL B CG1 1 
ATOM   9710  C  CG2 . VAL D 1 612 ? 85.125  129.665 134.835 1.00 95.02  ? 605 VAL B CG2 1 
ATOM   9711  N  N   . ILE D 1 613 ? 85.620  130.998 131.281 1.00 99.47  ? 606 ILE B N   1 
ATOM   9712  C  CA  . ILE D 1 613 ? 84.526  131.165 130.336 1.00 99.47  ? 606 ILE B CA  1 
ATOM   9713  C  C   . ILE D 1 613 ? 84.337  129.834 129.622 1.00 99.47  ? 606 ILE B C   1 
ATOM   9714  O  O   . ILE D 1 613 ? 85.319  129.197 129.221 1.00 99.47  ? 606 ILE B O   1 
ATOM   9715  C  CB  . ILE D 1 613 ? 84.807  132.298 129.331 1.00 99.47  ? 606 ILE B CB  1 
ATOM   9716  C  CG1 . ILE D 1 613 ? 83.822  132.246 128.161 1.00 99.47  ? 606 ILE B CG1 1 
ATOM   9717  C  CG2 . ILE D 1 613 ? 86.244  132.235 128.836 1.00 99.47  ? 606 ILE B CG2 1 
ATOM   9718  C  CD1 . ILE D 1 613 ? 83.608  133.582 127.487 1.00 99.47  ? 606 ILE B CD1 1 
ATOM   9719  N  N   . ASN D 1 614 ? 83.081  129.396 129.505 1.00 103.86 ? 607 ASN B N   1 
ATOM   9720  C  CA  . ASN D 1 614 ? 82.735  128.158 128.801 1.00 103.86 ? 607 ASN B CA  1 
ATOM   9721  C  C   . ASN D 1 614 ? 83.552  126.975 129.317 1.00 103.86 ? 607 ASN B C   1 
ATOM   9722  O  O   . ASN D 1 614 ? 83.976  126.106 128.553 1.00 103.86 ? 607 ASN B O   1 
ATOM   9723  C  CB  . ASN D 1 614 ? 82.908  128.321 127.290 1.00 103.86 ? 607 ASN B CB  1 
ATOM   9724  C  CG  . ASN D 1 614 ? 82.112  129.486 126.735 1.00 103.86 ? 607 ASN B CG  1 
ATOM   9725  O  OD1 . ASN D 1 614 ? 81.227  130.021 127.404 1.00 103.86 ? 607 ASN B OD1 1 
ATOM   9726  N  ND2 . ASN D 1 614 ? 82.424  129.885 125.508 1.00 103.86 ? 607 ASN B ND2 1 
ATOM   9727  N  N   . GLY D 1 615 ? 83.770  126.943 130.627 1.00 101.72 ? 608 GLY B N   1 
ATOM   9728  C  CA  . GLY D 1 615 ? 84.543  125.879 131.244 1.00 101.72 ? 608 GLY B CA  1 
ATOM   9729  C  C   . GLY D 1 615 ? 86.015  125.851 130.888 1.00 101.72 ? 608 GLY B C   1 
ATOM   9730  O  O   . GLY D 1 615 ? 86.599  124.765 130.785 1.00 101.72 ? 608 GLY B O   1 
ATOM   9731  N  N   . ARG D 1 616 ? 86.633  127.017 130.698 1.00 93.39  ? 609 ARG B N   1 
ATOM   9732  C  CA  . ARG D 1 616 ? 88.084  127.085 130.556 1.00 93.39  ? 609 ARG B CA  1 
ATOM   9733  C  C   . ARG D 1 616 ? 88.539  128.490 130.911 1.00 93.39  ? 609 ARG B C   1 
ATOM   9734  O  O   . ARG D 1 616 ? 87.902  129.464 130.508 1.00 93.39  ? 609 ARG B O   1 
ATOM   9735  C  CB  . ARG D 1 616 ? 88.532  126.720 129.137 1.00 93.39  ? 609 ARG B CB  1 
ATOM   9736  C  CG  . ARG D 1 616 ? 90.040  126.703 128.971 1.00 93.39  ? 609 ARG B CG  1 
ATOM   9737  C  CD  . ARG D 1 616 ? 90.490  125.575 128.057 1.00 93.39  ? 609 ARG B CD  1 
ATOM   9738  N  NE  . ARG D 1 616 ? 91.880  125.724 127.640 1.00 93.39  ? 609 ARG B NE  1 
ATOM   9739  C  CZ  . ARG D 1 616 ? 92.927  125.562 128.437 1.00 93.39  ? 609 ARG B CZ  1 
ATOM   9740  N  NH1 . ARG D 1 616 ? 92.785  125.232 129.710 1.00 93.39  ? 609 ARG B NH1 1 
ATOM   9741  N  NH2 . ARG D 1 616 ? 94.150  125.730 127.942 1.00 93.39  ? 609 ARG B NH2 1 
ATOM   9742  N  N   . CYS D 1 617 ? 89.625  128.594 131.670 1.00 89.11  ? 610 CYS B N   1 
ATOM   9743  C  CA  . CYS D 1 617 ? 90.093  129.902 132.107 1.00 89.11  ? 610 CYS B CA  1 
ATOM   9744  C  C   . CYS D 1 617 ? 90.686  130.677 130.936 1.00 89.11  ? 610 CYS B C   1 
ATOM   9745  O  O   . CYS D 1 617 ? 91.442  130.130 130.128 1.00 89.11  ? 610 CYS B O   1 
ATOM   9746  C  CB  . CYS D 1 617 ? 91.126  129.761 133.222 1.00 89.11  ? 610 CYS B CB  1 
ATOM   9747  S  SG  . CYS D 1 617 ? 92.255  131.161 133.347 1.00 89.11  ? 610 CYS B SG  1 
ATOM   9748  N  N   . CYS D 1 618 ? 90.336  131.963 130.851 1.00 84.00  ? 611 CYS B N   1 
ATOM   9749  C  CA  . CYS D 1 618 ? 90.789  132.783 129.732 1.00 84.00  ? 611 CYS B CA  1 
ATOM   9750  C  C   . CYS D 1 618 ? 92.304  132.946 129.736 1.00 84.00  ? 611 CYS B C   1 
ATOM   9751  O  O   . CYS D 1 618 ? 92.938  132.932 128.676 1.00 84.00  ? 611 CYS B O   1 
ATOM   9752  C  CB  . CYS D 1 618 ? 90.103  134.147 129.770 1.00 84.00  ? 611 CYS B CB  1 
ATOM   9753  S  SG  . CYS D 1 618 ? 90.247  135.009 131.349 1.00 84.00  ? 611 CYS B SG  1 
ATOM   9754  N  N   . LEU D 1 619 ? 92.899  133.114 130.919 1.00 77.51  ? 612 LEU B N   1 
ATOM   9755  C  CA  . LEU D 1 619 ? 94.348  133.274 131.003 1.00 77.51  ? 612 LEU B CA  1 
ATOM   9756  C  C   . LEU D 1 619 ? 95.073  132.033 130.495 1.00 77.51  ? 612 LEU B C   1 
ATOM   9757  O  O   . LEU D 1 619 ? 96.002  132.133 129.680 1.00 77.51  ? 612 LEU B O   1 
ATOM   9758  C  CB  . LEU D 1 619 ? 94.751  133.571 132.446 1.00 77.51  ? 612 LEU B CB  1 
ATOM   9759  C  CG  . LEU D 1 619 ? 95.023  135.029 132.804 1.00 77.51  ? 612 LEU B CG  1 
ATOM   9760  C  CD1 . LEU D 1 619 ? 95.196  135.181 134.302 1.00 77.51  ? 612 LEU B CD1 1 
ATOM   9761  C  CD2 . LEU D 1 619 ? 96.259  135.505 132.081 1.00 77.51  ? 612 LEU B CD2 1 
ATOM   9762  N  N   . GLU D 1 620 ? 94.660  130.854 130.967 1.00 81.33  ? 613 GLU B N   1 
ATOM   9763  C  CA  . GLU D 1 620 ? 95.289  129.617 130.518 1.00 81.33  ? 613 GLU B CA  1 
ATOM   9764  C  C   . GLU D 1 620 ? 95.090  129.413 129.024 1.00 81.33  ? 613 GLU B C   1 
ATOM   9765  O  O   . GLU D 1 620 ? 96.016  129.001 128.321 1.00 81.33  ? 613 GLU B O   1 
ATOM   9766  C  CB  . GLU D 1 620 ? 94.736  128.426 131.298 1.00 81.33  ? 613 GLU B CB  1 
ATOM   9767  C  CG  . GLU D 1 620 ? 94.570  128.667 132.783 1.00 81.33  ? 613 GLU B CG  1 
ATOM   9768  C  CD  . GLU D 1 620 ? 94.453  127.379 133.569 1.00 81.33  ? 613 GLU B CD  1 
ATOM   9769  O  OE1 . GLU D 1 620 ? 94.343  126.306 132.941 1.00 81.33  ? 613 GLU B OE1 1 
ATOM   9770  O  OE2 . GLU D 1 620 ? 94.464  127.438 134.816 1.00 81.33  ? 613 GLU B OE2 1 
ATOM   9771  N  N   . GLU D 1 621 ? 93.885  129.691 128.522 1.00 84.31  ? 614 GLU B N   1 
ATOM   9772  C  CA  . GLU D 1 621 ? 93.624  129.531 127.095 1.00 84.31  ? 614 GLU B CA  1 
ATOM   9773  C  C   . GLU D 1 621 ? 94.516  130.448 126.269 1.00 84.31  ? 614 GLU B C   1 
ATOM   9774  O  O   . GLU D 1 621 ? 95.094  130.028 125.260 1.00 84.31  ? 614 GLU B O   1 
ATOM   9775  C  CB  . GLU D 1 621 ? 92.150  129.804 126.798 1.00 84.31  ? 614 GLU B CB  1 
ATOM   9776  C  CG  . GLU D 1 621 ? 91.785  129.731 125.324 1.00 84.31  ? 614 GLU B CG  1 
ATOM   9777  C  CD  . GLU D 1 621 ? 91.631  128.306 124.827 1.00 84.31  ? 614 GLU B CD  1 
ATOM   9778  O  OE1 . GLU D 1 621 ? 91.728  127.372 125.649 1.00 84.31  ? 614 GLU B OE1 1 
ATOM   9779  O  OE2 . GLU D 1 621 ? 91.413  128.122 123.612 1.00 84.31  ? 614 GLU B OE2 1 
ATOM   9780  N  N   . LYS D 1 622 ? 94.645  131.707 126.690 1.00 78.82  ? 615 LYS B N   1 
ATOM   9781  C  CA  . LYS D 1 622 ? 95.471  132.659 125.954 1.00 78.82  ? 615 LYS B CA  1 
ATOM   9782  C  C   . LYS D 1 622 ? 96.930  132.225 125.945 1.00 78.82  ? 615 LYS B C   1 
ATOM   9783  O  O   . LYS D 1 622 ? 97.585  132.227 124.897 1.00 78.82  ? 615 LYS B O   1 
ATOM   9784  C  CB  . LYS D 1 622 ? 95.326  134.052 126.567 1.00 78.82  ? 615 LYS B CB  1 
ATOM   9785  C  CG  . LYS D 1 622 ? 96.355  135.060 126.088 1.00 78.82  ? 615 LYS B CG  1 
ATOM   9786  C  CD  . LYS D 1 622 ? 96.114  135.456 124.643 1.00 78.82  ? 615 LYS B CD  1 
ATOM   9787  C  CE  . LYS D 1 622 ? 97.153  136.458 124.170 1.00 78.82  ? 615 LYS B CE  1 
ATOM   9788  N  NZ  . LYS D 1 622 ? 97.161  137.686 125.011 1.00 78.82  ? 615 LYS B NZ  1 
ATOM   9789  N  N   . VAL D 1 623 ? 97.452  131.826 127.105 1.00 75.74  ? 616 VAL B N   1 
ATOM   9790  C  CA  . VAL D 1 623 ? 98.864  131.458 127.180 1.00 75.74  ? 616 VAL B CA  1 
ATOM   9791  C  C   . VAL D 1 623 ? 99.122  130.168 126.410 1.00 75.74  ? 616 VAL B C   1 
ATOM   9792  O  O   . VAL D 1 623 ? 100.169 130.004 125.771 1.00 75.74  ? 616 VAL B O   1 
ATOM   9793  C  CB  . VAL D 1 623 ? 99.311  131.357 128.647 1.00 75.74  ? 616 VAL B CB  1 
ATOM   9794  C  CG1 . VAL D 1 623 ? 100.723 130.812 128.743 1.00 75.74  ? 616 VAL B CG1 1 
ATOM   9795  C  CG2 . VAL D 1 623 ? 99.231  132.725 129.284 1.00 75.74  ? 616 VAL B CG2 1 
ATOM   9796  N  N   . CYS D 1 624 ? 98.171  129.233 126.453 1.00 79.45  ? 617 CYS B N   1 
ATOM   9797  C  CA  . CYS D 1 624 ? 98.318  127.992 125.700 1.00 79.45  ? 617 CYS B CA  1 
ATOM   9798  C  C   . CYS D 1 624 ? 98.290  128.255 124.201 1.00 79.45  ? 617 CYS B C   1 
ATOM   9799  O  O   . CYS D 1 624 ? 99.065  127.666 123.443 1.00 79.45  ? 617 CYS B O   1 
ATOM   9800  C  CB  . CYS D 1 624 ? 97.225  127.003 126.099 1.00 79.45  ? 617 CYS B CB  1 
ATOM   9801  S  SG  . CYS D 1 624 ? 97.290  125.425 125.217 1.00 79.45  ? 617 CYS B SG  1 
ATOM   9802  N  N   . SER D 1 625 ? 97.402  129.144 123.750 1.00 76.07  ? 618 SER B N   1 
ATOM   9803  C  CA  . SER D 1 625 ? 97.370  129.500 122.338 1.00 76.07  ? 618 SER B CA  1 
ATOM   9804  C  C   . SER D 1 625 ? 98.572  130.330 121.918 1.00 76.07  ? 618 SER B C   1 
ATOM   9805  O  O   . SER D 1 625 ? 98.865  130.405 120.720 1.00 76.07  ? 618 SER B O   1 
ATOM   9806  C  CB  . SER D 1 625 ? 96.083  130.260 122.015 1.00 76.07  ? 618 SER B CB  1 
ATOM   9807  O  OG  . SER D 1 625 ? 96.111  130.760 120.690 1.00 76.07  ? 618 SER B OG  1 
ATOM   9808  N  N   . LEU D 1 626 ? 99.262  130.963 122.866 1.00 72.49  ? 619 LEU B N   1 
ATOM   9809  C  CA  . LEU D 1 626 ? 100.459 131.733 122.558 1.00 72.49  ? 619 LEU B CA  1 
ATOM   9810  C  C   . LEU D 1 626 ? 101.729 130.890 122.553 1.00 72.49  ? 619 LEU B C   1 
ATOM   9811  O  O   . LEU D 1 626 ? 102.650 131.192 121.787 1.00 72.49  ? 619 LEU B O   1 
ATOM   9812  C  CB  . LEU D 1 626 ? 100.609 132.877 123.571 1.00 72.49  ? 619 LEU B CB  1 
ATOM   9813  C  CG  . LEU D 1 626 ? 101.669 133.964 123.390 1.00 72.49  ? 619 LEU B CG  1 
ATOM   9814  C  CD1 . LEU D 1 626 ? 101.957 134.237 121.920 1.00 72.49  ? 619 LEU B CD1 1 
ATOM   9815  C  CD2 . LEU D 1 626 ? 101.231 135.238 124.095 1.00 72.49  ? 619 LEU B CD2 1 
ATOM   9816  N  N   . LEU D 1 627 ? 101.760 129.818 123.352 1.00 72.96  ? 620 LEU B N   1 
ATOM   9817  C  CA  . LEU D 1 627 ? 103.007 129.010 123.475 1.00 72.96  ? 620 LEU B CA  1 
ATOM   9818  C  C   . LEU D 1 627 ? 102.916 127.715 122.658 1.00 72.96  ? 620 LEU B C   1 
ATOM   9819  O  O   . LEU D 1 627 ? 103.971 127.256 122.183 1.00 72.96  ? 620 LEU B O   1 
ATOM   9820  C  CB  . LEU D 1 627 ? 103.248 128.705 124.957 1.00 72.96  ? 620 LEU B CB  1 
ATOM   9821  C  CG  . LEU D 1 627 ? 103.503 129.925 125.841 1.00 72.96  ? 620 LEU B CG  1 
ATOM   9822  C  CD1 . LEU D 1 627 ? 104.075 129.512 127.188 1.00 72.96  ? 620 LEU B CD1 1 
ATOM   9823  C  CD2 . LEU D 1 627 ? 104.430 130.912 125.148 1.00 72.96  ? 620 LEU B CD2 1 
ATOM   9824  N  N   . GLU D 1 628 ? 101.718 127.141 122.504 1.00 76.22  ? 621 GLU B N   1 
ATOM   9825  C  CA  . GLU D 1 628 ? 101.597 125.863 121.804 1.00 76.22  ? 621 GLU B CA  1 
ATOM   9826  C  C   . GLU D 1 628 ? 102.092 125.916 120.363 1.00 76.22  ? 621 GLU B C   1 
ATOM   9827  O  O   . GLU D 1 628 ? 102.842 125.008 119.961 1.00 76.22  ? 621 GLU B O   1 
ATOM   9828  C  CB  . GLU D 1 628 ? 100.148 125.369 121.888 1.00 76.22  ? 621 GLU B CB  1 
ATOM   9829  C  CG  . GLU D 1 628 ? 99.836  124.123 121.065 1.00 76.22  ? 621 GLU B CG  1 
ATOM   9830  C  CD  . GLU D 1 628 ? 99.466  124.439 119.627 1.00 76.22  ? 621 GLU B CD  1 
ATOM   9831  O  OE1 . GLU D 1 628 ? 98.995  125.565 119.367 1.00 76.22  ? 621 GLU B OE1 1 
ATOM   9832  O  OE2 . GLU D 1 628 ? 99.648  123.560 118.758 1.00 76.22  ? 621 GLU B OE2 1 
ATOM   9833  N  N   . PRO D 1 629 ? 101.728 126.920 119.526 1.00 74.16  ? 622 PRO B N   1 
ATOM   9834  C  CA  . PRO D 1 629 ? 102.167 126.881 118.122 1.00 74.16  ? 622 PRO B CA  1 
ATOM   9835  C  C   . PRO D 1 629 ? 103.676 126.974 117.961 1.00 74.16  ? 622 PRO B C   1 
ATOM   9836  O  O   . PRO D 1 629 ? 104.197 126.859 116.847 1.00 74.16  ? 622 PRO B O   1 
ATOM   9837  C  CB  . PRO D 1 629 ? 101.455 128.085 117.496 1.00 74.16  ? 622 PRO B CB  1 
ATOM   9838  C  CG  . PRO D 1 629 ? 101.248 129.020 118.612 1.00 74.16  ? 622 PRO B CG  1 
ATOM   9839  C  CD  . PRO D 1 629 ? 100.993 128.164 119.820 1.00 74.16  ? 622 PRO B CD  1 
ATOM   9840  N  N   . LEU D 1 630 ? 104.387 127.191 119.064 1.00 66.18  ? 623 LEU B N   1 
ATOM   9841  C  CA  . LEU D 1 630 ? 105.835 127.067 119.081 1.00 66.18  ? 623 LEU B CA  1 
ATOM   9842  C  C   . LEU D 1 630 ? 106.287 125.620 119.244 1.00 66.18  ? 623 LEU B C   1 
ATOM   9843  O  O   . LEU D 1 630 ? 107.474 125.331 119.062 1.00 66.18  ? 623 LEU B O   1 
ATOM   9844  C  CB  . LEU D 1 630 ? 106.422 127.928 120.206 1.00 66.18  ? 623 LEU B CB  1 
ATOM   9845  C  CG  . LEU D 1 630 ? 107.934 128.150 120.221 1.00 66.18  ? 623 LEU B CG  1 
ATOM   9846  C  CD1 . LEU D 1 630 ? 108.420 128.437 118.813 1.00 66.18  ? 623 LEU B CD1 1 
ATOM   9847  C  CD2 . LEU D 1 630 ? 108.311 129.275 121.167 1.00 66.18  ? 623 LEU B CD2 1 
ATOM   9848  N  N   . GLY D 1 631 ? 105.369 124.707 119.556 1.00 72.63  ? 624 GLY B N   1 
ATOM   9849  C  CA  . GLY D 1 631 ? 105.702 123.302 119.697 1.00 72.63  ? 624 GLY B CA  1 
ATOM   9850  C  C   . GLY D 1 631 ? 105.960 122.867 121.124 1.00 72.63  ? 624 GLY B C   1 
ATOM   9851  O  O   . GLY D 1 631 ? 106.984 122.240 121.411 1.00 72.63  ? 624 GLY B O   1 
ATOM   9852  N  N   . LEU D 1 632 ? 105.036 123.188 122.029 1.00 70.00  ? 625 LEU B N   1 
ATOM   9853  C  CA  . LEU D 1 632 ? 105.191 122.868 123.440 1.00 70.00  ? 625 LEU B CA  1 
ATOM   9854  C  C   . LEU D 1 632 ? 103.891 122.295 123.985 1.00 70.00  ? 625 LEU B C   1 
ATOM   9855  O  O   . LEU D 1 632 ? 102.832 122.389 123.361 1.00 70.00  ? 625 LEU B O   1 
ATOM   9856  C  CB  . LEU D 1 632 ? 105.584 124.101 124.261 1.00 70.00  ? 625 LEU B CB  1 
ATOM   9857  C  CG  . LEU D 1 632 ? 106.854 124.849 123.869 1.00 70.00  ? 625 LEU B CG  1 
ATOM   9858  C  CD1 . LEU D 1 632 ? 107.031 126.041 124.781 1.00 70.00  ? 625 LEU B CD1 1 
ATOM   9859  C  CD2 . LEU D 1 632 ? 108.058 123.934 123.944 1.00 70.00  ? 625 LEU B CD2 1 
ATOM   9860  N  N   . GLN D 1 633 ? 103.990 121.692 125.167 1.00 70.15  ? 626 GLN B N   1 
ATOM   9861  C  CA  . GLN D 1 633 ? 102.839 121.248 125.938 1.00 70.15  ? 626 GLN B CA  1 
ATOM   9862  C  C   . GLN D 1 633 ? 102.832 121.980 127.271 1.00 70.15  ? 626 GLN B C   1 
ATOM   9863  O  O   . GLN D 1 633 ? 103.869 122.091 127.932 1.00 70.15  ? 626 GLN B O   1 
ATOM   9864  C  CB  . GLN D 1 633 ? 102.865 119.734 126.171 1.00 70.15  ? 626 GLN B CB  1 
ATOM   9865  C  CG  . GLN D 1 633 ? 102.469 118.911 124.961 1.00 70.15  ? 626 GLN B CG  1 
ATOM   9866  C  CD  . GLN D 1 633 ? 103.606 118.739 123.977 1.00 70.15  ? 626 GLN B CD  1 
ATOM   9867  O  OE1 . GLN D 1 633 ? 104.626 118.126 124.291 1.00 70.15  ? 626 GLN B OE1 1 
ATOM   9868  N  NE2 . GLN D 1 633 ? 103.437 119.283 122.778 1.00 70.15  ? 626 GLN B NE2 1 
ATOM   9869  N  N   . CYS D 1 634 ? 101.664 122.477 127.666 1.00 72.75  ? 627 CYS B N   1 
ATOM   9870  C  CA  . CYS D 1 634 ? 101.525 123.287 128.867 1.00 72.75  ? 627 CYS B CA  1 
ATOM   9871  C  C   . CYS D 1 634 ? 100.718 122.533 129.911 1.00 72.75  ? 627 CYS B C   1 
ATOM   9872  O  O   . CYS D 1 634 ? 99.588  122.109 129.644 1.00 72.75  ? 627 CYS B O   1 
ATOM   9873  C  CB  . CYS D 1 634 ? 100.853 124.624 128.546 1.00 72.75  ? 627 CYS B CB  1 
ATOM   9874  S  SG  . CYS D 1 634 ? 101.462 125.416 127.043 1.00 72.75  ? 627 CYS B SG  1 
ATOM   9875  N  N   . THR D 1 635 ? 101.299 122.368 131.097 1.00 70.46  ? 628 THR B N   1 
ATOM   9876  C  CA  . THR D 1 635 ? 100.617 121.789 132.247 1.00 70.46  ? 628 THR B CA  1 
ATOM   9877  C  C   . THR D 1 635 ? 100.672 122.781 133.398 1.00 70.46  ? 628 THR B C   1 
ATOM   9878  O  O   . THR D 1 635 ? 101.753 123.255 133.762 1.00 70.46  ? 628 THR B O   1 
ATOM   9879  C  CB  . THR D 1 635 ? 101.251 120.460 132.671 1.00 70.46  ? 628 THR B CB  1 
ATOM   9880  O  OG1 . THR D 1 635 ? 102.415 120.717 133.467 1.00 70.46  ? 628 THR B OG1 1 
ATOM   9881  C  CG2 . THR D 1 635 ? 101.647 119.639 131.454 1.00 70.46  ? 628 THR B CG2 1 
ATOM   9882  N  N   . PHE D 1 636 ? 99.513  123.089 133.967 1.00 69.67  ? 629 PHE B N   1 
ATOM   9883  C  CA  . PHE D 1 636 ? 99.405  124.054 135.053 1.00 69.67  ? 629 PHE B CA  1 
ATOM   9884  C  C   . PHE D 1 636 ? 99.358  123.318 136.384 1.00 69.67  ? 629 PHE B C   1 
ATOM   9885  O  O   . PHE D 1 636 ? 98.569  122.383 136.554 1.00 69.67  ? 629 PHE B O   1 
ATOM   9886  C  CB  . PHE D 1 636 ? 98.159  124.926 134.887 1.00 69.67  ? 629 PHE B CB  1 
ATOM   9887  C  CG  . PHE D 1 636 ? 98.171  125.773 133.647 1.00 69.67  ? 629 PHE B CG  1 
ATOM   9888  C  CD1 . PHE D 1 636 ? 97.679  125.280 132.451 1.00 69.67  ? 629 PHE B CD1 1 
ATOM   9889  C  CD2 . PHE D 1 636 ? 98.668  127.062 133.677 1.00 69.67  ? 629 PHE B CD2 1 
ATOM   9890  C  CE1 . PHE D 1 636 ? 97.687  126.057 131.310 1.00 69.67  ? 629 PHE B CE1 1 
ATOM   9891  C  CE2 . PHE D 1 636 ? 98.679  127.843 132.539 1.00 69.67  ? 629 PHE B CE2 1 
ATOM   9892  C  CZ  . PHE D 1 636 ? 98.188  127.339 131.354 1.00 69.67  ? 629 PHE B CZ  1 
ATOM   9893  N  N   . ILE D 1 637 ? 100.250 123.747 137.286 1.00 66.24  ? 630 ILE B N   1 
ATOM   9894  C  CA  . ILE D 1 637 ? 100.333 123.149 138.647 1.00 66.24  ? 630 ILE B CA  1 
ATOM   9895  C  C   . ILE D 1 637 ? 99.827  124.200 139.635 1.00 66.24  ? 630 ILE B C   1 
ATOM   9896  O  O   . ILE D 1 637 ? 100.088 125.395 139.405 1.00 66.24  ? 630 ILE B O   1 
ATOM   9897  C  CB  . ILE D 1 637 ? 101.788 122.749 138.960 1.00 66.24  ? 630 ILE B CB  1 
ATOM   9898  C  CG1 . ILE D 1 637 ? 102.412 121.935 137.823 1.00 66.24  ? 630 ILE B CG1 1 
ATOM   9899  C  CG2 . ILE D 1 637 ? 101.881 122.023 140.293 1.00 66.24  ? 630 ILE B CG2 1 
ATOM   9900  C  CD1 . ILE D 1 637 ? 103.874 121.621 138.030 1.00 66.24  ? 630 ILE B CD1 1 
ATOM   9901  N  N   . ASN D 1 638 ? 99.136  123.770 140.689 1.00 73.54  ? 631 ASN B N   1 
ATOM   9902  C  CA  . ASN D 1 638 ? 98.598  124.683 141.688 1.00 73.54  ? 631 ASN B CA  1 
ATOM   9903  C  C   . ASN D 1 638 ? 99.517  124.723 142.904 1.00 73.54  ? 631 ASN B C   1 
ATOM   9904  O  O   . ASN D 1 638 ? 99.800  123.684 143.511 1.00 73.54  ? 631 ASN B O   1 
ATOM   9905  C  CB  . ASN D 1 638 ? 97.185  124.263 142.091 1.00 73.54  ? 631 ASN B CB  1 
ATOM   9906  C  CG  . ASN D 1 638 ? 97.073  122.775 142.349 1.00 73.54  ? 631 ASN B CG  1 
ATOM   9907  O  OD1 . ASN D 1 638 ? 97.845  121.979 141.813 1.00 73.54  ? 631 ASN B OD1 1 
ATOM   9908  N  ND2 . ASN D 1 638 ? 96.105  122.388 143.171 1.00 73.54  ? 631 ASN B ND2 1 
ATOM   9909  N  N   . ASP D 1 639 ? 99.980  125.925 143.254 1.00 78.29  ? 632 ASP B N   1 
ATOM   9910  C  CA  . ASP D 1 639 ? 100.798 126.133 144.442 1.00 78.29  ? 632 ASP B CA  1 
ATOM   9911  C  C   . ASP D 1 639 ? 100.386 127.403 145.178 1.00 78.29  ? 632 ASP B C   1 
ATOM   9912  O  O   . ASP D 1 639 ? 101.227 128.075 145.785 1.00 78.29  ? 632 ASP B O   1 
ATOM   9913  C  CB  . ASP D 1 639 ? 102.284 126.193 144.085 1.00 78.29  ? 632 ASP B CB  1 
ATOM   9914  C  CG  . ASP D 1 639 ? 102.580 127.194 142.986 1.00 78.29  ? 632 ASP B CG  1 
ATOM   9915  O  OD1 . ASP D 1 639 ? 102.448 128.410 143.231 1.00 78.29  ? 632 ASP B OD1 1 
ATOM   9916  O  OD2 . ASP D 1 639 ? 102.947 126.762 141.875 1.00 78.29  ? 632 ASP B OD2 1 
ATOM   9917  N  N   . PHE D 1 640 ? 99.098  127.749 145.124 1.00 86.22  ? 633 PHE B N   1 
ATOM   9918  C  CA  . PHE D 1 640 ? 98.635  129.005 145.704 1.00 86.22  ? 633 PHE B CA  1 
ATOM   9919  C  C   . PHE D 1 640 ? 98.769  128.999 147.223 1.00 86.22  ? 633 PHE B C   1 
ATOM   9920  O  O   . PHE D 1 640 ? 99.335  129.931 147.809 1.00 86.22  ? 633 PHE B O   1 
ATOM   9921  C  CB  . PHE D 1 640 ? 97.186  129.260 145.286 1.00 86.22  ? 633 PHE B CB  1 
ATOM   9922  C  CG  . PHE D 1 640 ? 96.775  130.704 145.344 1.00 86.22  ? 633 PHE B CG  1 
ATOM   9923  C  CD1 . PHE D 1 640 ? 96.894  131.434 146.515 1.00 86.22  ? 633 PHE B CD1 1 
ATOM   9924  C  CD2 . PHE D 1 640 ? 96.273  131.331 144.220 1.00 86.22  ? 633 PHE B CD2 1 
ATOM   9925  C  CE1 . PHE D 1 640 ? 96.516  132.759 146.563 1.00 86.22  ? 633 PHE B CE1 1 
ATOM   9926  C  CE2 . PHE D 1 640 ? 95.896  132.655 144.262 1.00 86.22  ? 633 PHE B CE2 1 
ATOM   9927  C  CZ  . PHE D 1 640 ? 96.017  133.371 145.435 1.00 86.22  ? 633 PHE B CZ  1 
ATOM   9928  N  N   . PHE D 1 641 ? 98.258  127.960 147.880 1.00 92.29  ? 634 PHE B N   1 
ATOM   9929  C  CA  . PHE D 1 641 ? 98.267  127.916 149.337 1.00 92.29  ? 634 PHE B CA  1 
ATOM   9930  C  C   . PHE D 1 641 ? 99.617  127.529 149.922 1.00 92.29  ? 634 PHE B C   1 
ATOM   9931  O  O   . PHE D 1 641 ? 99.841  127.758 151.115 1.00 92.29  ? 634 PHE B O   1 
ATOM   9932  C  CB  . PHE D 1 641 ? 97.200  126.941 149.842 1.00 92.29  ? 634 PHE B CB  1 
ATOM   9933  C  CG  . PHE D 1 641 ? 95.803  127.484 149.774 1.00 92.29  ? 634 PHE B CG  1 
ATOM   9934  C  CD1 . PHE D 1 641 ? 95.506  128.734 150.289 1.00 92.29  ? 634 PHE B CD1 1 
ATOM   9935  C  CD2 . PHE D 1 641 ? 94.784  126.739 149.205 1.00 92.29  ? 634 PHE B CD2 1 
ATOM   9936  C  CE1 . PHE D 1 641 ? 94.221  129.236 150.232 1.00 92.29  ? 634 PHE B CE1 1 
ATOM   9937  C  CE2 . PHE D 1 641 ? 93.496  127.235 149.145 1.00 92.29  ? 634 PHE B CE2 1 
ATOM   9938  C  CZ  . PHE D 1 641 ? 93.215  128.485 149.659 1.00 92.29  ? 634 PHE B CZ  1 
ATOM   9939  N  N   . THR D 1 642 ? 100.518 126.958 149.125 1.00 83.55  ? 635 THR B N   1 
ATOM   9940  C  CA  . THR D 1 642 ? 101.796 126.478 149.631 1.00 83.55  ? 635 THR B CA  1 
ATOM   9941  C  C   . THR D 1 642 ? 102.982 127.342 149.238 1.00 83.55  ? 635 THR B C   1 
ATOM   9942  O  O   . THR D 1 642 ? 103.966 127.381 149.976 1.00 83.55  ? 635 THR B O   1 
ATOM   9943  C  CB  . THR D 1 642 ? 102.055 125.044 149.153 1.00 83.55  ? 635 THR B CB  1 
ATOM   9944  O  OG1 . THR D 1 642 ? 102.722 125.077 147.886 1.00 83.55  ? 635 THR B OG1 1 
ATOM   9945  C  CG2 . THR D 1 642 ? 100.745 124.284 149.011 1.00 83.55  ? 635 THR B CG2 1 
ATOM   9946  N  N   . TYR D 1 643 ? 102.920 128.031 148.100 1.00 77.20  ? 636 TYR B N   1 
ATOM   9947  C  CA  . TYR D 1 643 ? 104.025 128.864 147.646 1.00 77.20  ? 636 TYR B CA  1 
ATOM   9948  C  C   . TYR D 1 643 ? 103.643 130.328 147.503 1.00 77.20  ? 636 TYR B C   1 
ATOM   9949  O  O   . TYR D 1 643 ? 104.353 131.202 148.020 1.00 77.20  ? 636 TYR B O   1 
ATOM   9950  C  CB  . TYR D 1 643 ? 104.567 128.332 146.311 1.00 77.20  ? 636 TYR B CB  1 
ATOM   9951  C  CG  . TYR D 1 643 ? 105.705 127.353 146.470 1.00 77.20  ? 636 TYR B CG  1 
ATOM   9952  C  CD1 . TYR D 1 643 ? 105.477 126.067 146.934 1.00 77.20  ? 636 TYR B CD1 1 
ATOM   9953  C  CD2 . TYR D 1 643 ? 107.007 127.718 146.162 1.00 77.20  ? 636 TYR B CD2 1 
ATOM   9954  C  CE1 . TYR D 1 643 ? 106.512 125.168 147.083 1.00 77.20  ? 636 TYR B CE1 1 
ATOM   9955  C  CE2 . TYR D 1 643 ? 108.048 126.827 146.308 1.00 77.20  ? 636 TYR B CE2 1 
ATOM   9956  C  CZ  . TYR D 1 643 ? 107.795 125.553 146.770 1.00 77.20  ? 636 TYR B CZ  1 
ATOM   9957  O  OH  . TYR D 1 643 ? 108.830 124.661 146.918 1.00 77.20  ? 636 TYR B OH  1 
ATOM   9958  N  N   . HIS D 1 644 ? 102.528 130.622 146.829 1.00 75.06  ? 637 HIS B N   1 
ATOM   9959  C  CA  . HIS D 1 644 ? 102.168 132.010 146.556 1.00 75.06  ? 637 HIS B CA  1 
ATOM   9960  C  C   . HIS D 1 644 ? 101.971 132.798 147.844 1.00 75.06  ? 637 HIS B C   1 
ATOM   9961  O  O   . HIS D 1 644 ? 102.302 133.988 147.906 1.00 75.06  ? 637 HIS B O   1 
ATOM   9962  C  CB  . HIS D 1 644 ? 100.906 132.067 145.702 1.00 75.06  ? 637 HIS B CB  1 
ATOM   9963  C  CG  . HIS D 1 644 ? 100.606 133.428 145.157 1.00 75.06  ? 637 HIS B CG  1 
ATOM   9964  N  ND1 . HIS D 1 644 ? 101.230 134.570 145.612 1.00 75.06  ? 637 HIS B ND1 1 
ATOM   9965  C  CD2 . HIS D 1 644 ? 99.736  133.830 144.203 1.00 75.06  ? 637 HIS B CD2 1 
ATOM   9966  C  CE1 . HIS D 1 644 ? 100.762 135.615 144.955 1.00 75.06  ? 637 HIS B CE1 1 
ATOM   9967  N  NE2 . HIS D 1 644 ? 99.855  135.194 144.095 1.00 75.06  ? 637 HIS B NE2 1 
ATOM   9968  N  N   . ILE D 1 645 ? 101.424 132.155 148.878 1.00 79.81  ? 638 ILE B N   1 
ATOM   9969  C  CA  . ILE D 1 645 ? 101.216 132.840 150.148 1.00 79.81  ? 638 ILE B CA  1 
ATOM   9970  C  C   . ILE D 1 645 ? 102.539 133.352 150.702 1.00 79.81  ? 638 ILE B C   1 
ATOM   9971  O  O   . ILE D 1 645 ? 102.595 134.433 151.300 1.00 79.81  ? 638 ILE B O   1 
ATOM   9972  C  CB  . ILE D 1 645 ? 100.493 131.906 151.140 1.00 79.81  ? 638 ILE B CB  1 
ATOM   9973  C  CG1 . ILE D 1 645 ? 98.985  131.935 150.884 1.00 79.81  ? 638 ILE B CG1 1 
ATOM   9974  C  CG2 . ILE D 1 645 ? 100.790 132.289 152.581 1.00 79.81  ? 638 ILE B CG2 1 
ATOM   9975  C  CD1 . ILE D 1 645 ? 98.391  133.327 150.918 1.00 79.81  ? 638 ILE B CD1 1 
ATOM   9976  N  N   . ARG D 1 646 ? 103.624 132.612 150.484 1.00 78.52  ? 639 ARG B N   1 
ATOM   9977  C  CA  . ARG D 1 646 ? 104.949 133.033 150.922 1.00 78.52  ? 639 ARG B CA  1 
ATOM   9978  C  C   . ARG D 1 646 ? 105.746 133.684 149.794 1.00 78.52  ? 639 ARG B C   1 
ATOM   9979  O  O   . ARG D 1 646 ? 106.978 133.682 149.820 1.00 78.52  ? 639 ARG B O   1 
ATOM   9980  C  CB  . ARG D 1 646 ? 105.717 131.855 151.521 1.00 78.52  ? 639 ARG B CB  1 
ATOM   9981  C  CG  . ARG D 1 646 ? 105.113 131.324 152.816 1.00 78.52  ? 639 ARG B CG  1 
ATOM   9982  C  CD  . ARG D 1 646 ? 105.593 129.916 153.131 1.00 78.52  ? 639 ARG B CD  1 
ATOM   9983  N  NE  . ARG D 1 646 ? 104.737 128.893 152.545 1.00 78.52  ? 639 ARG B NE  1 
ATOM   9984  C  CZ  . ARG D 1 646 ? 103.797 128.233 153.208 1.00 78.52  ? 639 ARG B CZ  1 
ATOM   9985  N  NH1 . ARG D 1 646 ? 103.566 128.465 154.490 1.00 78.52  ? 639 ARG B NH1 1 
ATOM   9986  N  NH2 . ARG D 1 646 ? 103.074 127.317 152.572 1.00 78.52  ? 639 ARG B NH2 1 
ATOM   9987  N  N   . HIS D 1 647 ? 105.052 134.253 148.806 1.00 80.05  ? 640 HIS B N   1 
ATOM   9988  C  CA  . HIS D 1 647 ? 105.664 135.030 147.727 1.00 80.05  ? 640 HIS B CA  1 
ATOM   9989  C  C   . HIS D 1 647 ? 106.670 134.187 146.938 1.00 80.05  ? 640 HIS B C   1 
ATOM   9990  O  O   . HIS D 1 647 ? 107.872 134.456 146.910 1.00 80.05  ? 640 HIS B O   1 
ATOM   9991  C  CB  . HIS D 1 647 ? 106.330 136.298 148.276 1.00 80.05  ? 640 HIS B CB  1 
ATOM   9992  C  CG  . HIS D 1 647 ? 105.428 137.141 149.122 1.00 80.05  ? 640 HIS B CG  1 
ATOM   9993  N  ND1 . HIS D 1 647 ? 105.721 137.459 150.431 1.00 80.05  ? 640 HIS B ND1 1 
ATOM   9994  C  CD2 . HIS D 1 647 ? 104.243 137.735 148.846 1.00 80.05  ? 640 HIS B CD2 1 
ATOM   9995  C  CE1 . HIS D 1 647 ? 104.754 138.212 150.925 1.00 80.05  ? 640 HIS B CE1 1 
ATOM   9996  N  NE2 . HIS D 1 647 ? 103.845 138.393 149.984 1.00 80.05  ? 640 HIS B NE2 1 
ATOM   9997  N  N   . GLY D 1 648 ? 106.140 133.154 146.290 1.00 72.98  ? 641 GLY B N   1 
ATOM   9998  C  CA  . GLY D 1 648 ? 106.979 132.273 145.499 1.00 72.98  ? 641 GLY B CA  1 
ATOM   9999  C  C   . GLY D 1 648 ? 106.203 131.597 144.394 1.00 72.98  ? 641 GLY B C   1 
ATOM   10000 O  O   . GLY D 1 648 ? 104.970 131.631 144.359 1.00 72.98  ? 641 GLY B O   1 
ATOM   10001 N  N   . GLU D 1 649 ? 106.950 130.986 143.474 1.00 66.97  ? 642 GLU B N   1 
ATOM   10002 C  CA  . GLU D 1 649 ? 106.364 130.223 142.378 1.00 66.97  ? 642 GLU B CA  1 
ATOM   10003 C  C   . GLU D 1 649 ? 107.092 128.894 142.213 1.00 66.97  ? 642 GLU B C   1 
ATOM   10004 O  O   . GLU D 1 649 ? 107.946 128.549 143.035 1.00 66.97  ? 642 GLU B O   1 
ATOM   10005 C  CB  . GLU D 1 649 ? 106.403 131.027 141.077 1.00 66.97  ? 642 GLU B CB  1 
ATOM   10006 C  CG  . GLU D 1 649 ? 105.850 132.443 141.195 1.00 66.97  ? 642 GLU B CG  1 
ATOM   10007 C  CD  . GLU D 1 649 ? 104.338 132.478 141.319 1.00 66.97  ? 642 GLU B CD  1 
ATOM   10008 O  OE1 . GLU D 1 649 ? 103.697 131.420 141.152 1.00 66.97  ? 642 GLU B OE1 1 
ATOM   10009 O  OE2 . GLU D 1 649 ? 103.789 133.567 141.585 1.00 66.97  ? 642 GLU B OE2 1 
ATOM   10010 N  N   . VAL D 1 650 ? 106.720 128.132 141.180 1.00 63.76  ? 643 VAL B N   1 
ATOM   10011 C  CA  . VAL D 1 650 ? 107.296 126.764 141.001 1.00 63.76  ? 643 VAL B CA  1 
ATOM   10012 C  C   . VAL D 1 650 ? 108.805 126.846 140.763 1.00 63.76  ? 643 VAL B C   1 
ATOM   10013 O  O   . VAL D 1 650 ? 109.546 126.132 141.464 1.00 63.76  ? 643 VAL B O   1 
ATOM   10014 C  CB  . VAL D 1 650 ? 106.588 126.010 139.856 1.00 63.76  ? 643 VAL B CB  1 
ATOM   10015 C  CG1 . VAL D 1 650 ? 105.109 125.852 140.148 1.00 63.76  ? 643 VAL B CG1 1 
ATOM   10016 C  CG2 . VAL D 1 650 ? 106.778 126.681 138.504 1.00 63.76  ? 643 VAL B CG2 1 
ATOM   10017 N  N   . HIS D 1 651 ? 109.242 127.684 139.824 1.00 60.32  ? 644 HIS B N   1 
ATOM   10018 C  CA  . HIS D 1 651 ? 110.659 127.721 139.479 1.00 60.32  ? 644 HIS B CA  1 
ATOM   10019 C  C   . HIS D 1 651 ? 111.503 128.236 140.636 1.00 60.32  ? 644 HIS B C   1 
ATOM   10020 O  O   . HIS D 1 651 ? 112.689 127.901 140.733 1.00 60.32  ? 644 HIS B O   1 
ATOM   10021 C  CB  . HIS D 1 651 ? 110.881 128.576 138.233 1.00 60.32  ? 644 HIS B CB  1 
ATOM   10022 C  CG  . HIS D 1 651 ? 112.323 128.826 137.923 1.00 60.32  ? 644 HIS B CG  1 
ATOM   10023 N  ND1 . HIS D 1 651 ? 112.857 130.093 137.837 1.00 60.32  ? 644 HIS B ND1 1 
ATOM   10024 C  CD2 . HIS D 1 651 ? 113.347 127.970 137.693 1.00 60.32  ? 644 HIS B CD2 1 
ATOM   10025 C  CE1 . HIS D 1 651 ? 114.146 130.007 137.559 1.00 60.32  ? 644 HIS B CE1 1 
ATOM   10026 N  NE2 . HIS D 1 651 ? 114.468 128.730 137.468 1.00 60.32  ? 644 HIS B NE2 1 
ATOM   10027 N  N   . CYS D 1 652 ? 110.916 129.040 141.522 1.00 61.84  ? 645 CYS B N   1 
ATOM   10028 C  CA  . CYS D 1 652 ? 111.637 129.506 142.696 1.00 61.84  ? 645 CYS B CA  1 
ATOM   10029 C  C   . CYS D 1 652 ? 111.788 128.428 143.758 1.00 61.84  ? 645 CYS B C   1 
ATOM   10030 O  O   . CYS D 1 652 ? 112.552 128.625 144.708 1.00 61.84  ? 645 CYS B O   1 
ATOM   10031 C  CB  . CYS D 1 652 ? 110.933 130.725 143.296 1.00 30.00  ? 645 CYS B CB  1 
ATOM   10032 S  SG  . CYS D 1 652 ? 110.913 132.178 142.221 1.00 30.00  ? 645 CYS B SG  1 
ATOM   10033 N  N   . GLY D 1 653 ? 111.090 127.303 143.625 1.00 63.77  ? 646 GLY B N   1 
ATOM   10034 C  CA  . GLY D 1 653 ? 111.158 126.254 144.623 1.00 63.77  ? 646 GLY B CA  1 
ATOM   10035 C  C   . GLY D 1 653 ? 111.799 124.970 144.141 1.00 63.77  ? 646 GLY B C   1 
ATOM   10036 O  O   . GLY D 1 653 ? 111.921 124.010 144.906 1.00 63.77  ? 646 GLY B O   1 
ATOM   10037 N  N   . THR D 1 654 ? 112.205 124.931 142.873 1.00 57.09  ? 647 THR B N   1 
ATOM   10038 C  CA  . THR D 1 654 ? 112.847 123.758 142.297 1.00 57.09  ? 647 THR B CA  1 
ATOM   10039 C  C   . THR D 1 654 ? 114.075 124.186 141.508 1.00 57.09  ? 647 THR B C   1 
ATOM   10040 O  O   . THR D 1 654 ? 114.167 125.316 141.025 1.00 57.09  ? 647 THR B O   1 
ATOM   10041 C  CB  . THR D 1 654 ? 111.904 122.968 141.377 1.00 57.09  ? 647 THR B CB  1 
ATOM   10042 O  OG1 . THR D 1 654 ? 111.993 123.489 140.045 1.00 57.09  ? 647 THR B OG1 1 
ATOM   10043 C  CG2 . THR D 1 654 ? 110.462 123.043 141.857 1.00 57.09  ? 647 THR B CG2 1 
ATOM   10044 N  N   . ASN D 1 655 ? 115.023 123.261 141.376 1.00 48.49  ? 648 ASN B N   1 
ATOM   10045 C  CA  . ASN D 1 655 ? 116.239 123.483 140.610 1.00 48.49  ? 648 ASN B CA  1 
ATOM   10046 C  C   . ASN D 1 655 ? 116.440 122.346 139.622 1.00 48.49  ? 648 ASN B C   1 
ATOM   10047 O  O   . ASN D 1 655 ? 115.982 121.222 139.844 1.00 48.49  ? 648 ASN B O   1 
ATOM   10048 C  CB  . ASN D 1 655 ? 117.467 123.601 141.510 1.00 48.49  ? 648 ASN B CB  1 
ATOM   10049 C  CG  . ASN D 1 655 ? 118.451 124.630 141.007 1.00 48.49  ? 648 ASN B CG  1 
ATOM   10050 O  OD1 . ASN D 1 655 ? 118.542 124.881 139.807 1.00 48.49  ? 648 ASN B OD1 1 
ATOM   10051 N  ND2 . ASN D 1 655 ? 119.194 125.234 141.921 1.00 48.49  ? 648 ASN B ND2 1 
ATOM   10052 N  N   . VAL D 1 656 ? 117.129 122.650 138.525 1.00 39.84  ? 649 VAL B N   1 
ATOM   10053 C  CA  . VAL D 1 656 ? 117.350 121.706 137.437 1.00 39.84  ? 649 VAL B CA  1 
ATOM   10054 C  C   . VAL D 1 656 ? 118.825 121.718 137.065 1.00 39.84  ? 649 VAL B C   1 
ATOM   10055 O  O   . VAL D 1 656 ? 119.444 122.783 136.984 1.00 39.84  ? 649 VAL B O   1 
ATOM   10056 C  CB  . VAL D 1 656 ? 116.487 122.049 136.205 1.00 39.84  ? 649 VAL B CB  1 
ATOM   10057 C  CG1 . VAL D 1 656 ? 116.640 120.989 135.132 1.00 39.84  ? 649 VAL B CG1 1 
ATOM   10058 C  CG2 . VAL D 1 656 ? 115.032 122.205 136.595 1.00 39.84  ? 649 VAL B CG2 1 
ATOM   10059 N  N   . ARG D 1 657 ? 119.346 120.509 136.813 1.00 34.58  ? 650 ARG B N   1 
ATOM   10060 C  CA  . ARG D 1 657 ? 120.729 120.360 136.300 1.00 34.58  ? 650 ARG B CA  1 
ATOM   10061 C  C   . ARG D 1 657 ? 120.583 120.144 134.788 1.00 34.58  ? 650 ARG B C   1 
ATOM   10062 O  O   . ARG D 1 657 ? 119.622 119.448 134.390 1.00 34.58  ? 650 ARG B O   1 
ATOM   10063 C  CB  . ARG D 1 657 ? 121.419 119.186 137.001 1.00 34.58  ? 650 ARG B CB  1 
ATOM   10064 C  CG  . ARG D 1 657 ? 122.873 118.971 136.610 1.00 34.58  ? 650 ARG B CG  1 
ATOM   10065 C  CD  . ARG D 1 657 ? 123.041 117.754 135.716 1.00 34.58  ? 650 ARG B CD  1 
ATOM   10066 N  NE  . ARG D 1 657 ? 122.492 116.539 136.328 1.00 34.58  ? 650 ARG B NE  1 
ATOM   10067 C  CZ  . ARG D 1 657 ? 122.920 115.311 136.067 1.00 34.58  ? 650 ARG B CZ  1 
ATOM   10068 N  NH1 . ARG D 1 657 ? 124.071 115.133 135.446 1.00 34.58  ? 650 ARG B NH1 1 
ATOM   10069 N  NH2 . ARG D 1 657 ? 122.194 114.265 136.419 1.00 34.58  ? 650 ARG B NH2 1 
ATOM   10070 N  N   . ARG D 1 658 ? 121.493 120.685 133.979 1.00 33.75  ? 651 ARG B N   1 
ATOM   10071 C  CA  . ARG D 1 658 ? 121.372 120.644 132.532 1.00 33.75  ? 651 ARG B CA  1 
ATOM   10072 C  C   . ARG D 1 658 ? 122.688 120.226 131.896 1.00 33.75  ? 651 ARG B C   1 
ATOM   10073 O  O   . ARG D 1 658 ? 123.766 120.443 132.456 1.00 33.75  ? 651 ARG B O   1 
ATOM   10074 C  CB  . ARG D 1 658 ? 120.920 122.001 131.993 1.00 33.75  ? 651 ARG B CB  1 
ATOM   10075 C  CG  . ARG D 1 658 ? 119.417 122.153 132.026 1.00 33.75  ? 651 ARG B CG  1 
ATOM   10076 C  CD  . ARG D 1 658 ? 118.975 123.593 132.018 1.00 33.75  ? 651 ARG B CD  1 
ATOM   10077 N  NE  . ARG D 1 658 ? 117.589 123.692 131.581 1.00 33.75  ? 651 ARG B NE  1 
ATOM   10078 C  CZ  . ARG D 1 658 ? 116.569 123.958 132.385 1.00 33.75  ? 651 ARG B CZ  1 
ATOM   10079 N  NH1 . ARG D 1 658 ? 116.746 124.180 133.676 1.00 33.75  ? 651 ARG B NH1 1 
ATOM   10080 N  NH2 . ARG D 1 658 ? 115.340 123.997 131.880 1.00 33.75  ? 651 ARG B NH2 1 
ATOM   10081 N  N   . LYS D 1 659 ? 122.583 119.619 130.718 1.00 29.58  ? 652 LYS B N   1 
ATOM   10082 C  CA  . LYS D 1 659 ? 123.757 119.107 130.032 1.00 29.58  ? 652 LYS B CA  1 
ATOM   10083 C  C   . LYS D 1 659 ? 124.679 120.257 129.629 1.00 29.58  ? 652 LYS B C   1 
ATOM   10084 O  O   . LYS D 1 659 ? 124.208 121.296 129.157 1.00 29.58  ? 652 LYS B O   1 
ATOM   10085 C  CB  . LYS D 1 659 ? 123.349 118.305 128.797 1.00 29.58  ? 652 LYS B CB  1 
ATOM   10086 C  CG  . LYS D 1 659 ? 124.520 117.872 127.927 1.00 29.58  ? 652 LYS B CG  1 
ATOM   10087 C  CD  . LYS D 1 659 ? 124.062 117.358 126.579 1.00 29.58  ? 652 LYS B CD  1 
ATOM   10088 C  CE  . LYS D 1 659 ? 125.241 117.189 125.635 1.00 29.58  ? 652 LYS B CE  1 
ATOM   10089 N  NZ  . LYS D 1 659 ? 124.803 116.889 124.244 1.00 29.58  ? 652 LYS B NZ  1 
ATOM   10090 N  N   . PRO D 1 660 ? 125.991 120.104 129.804 1.00 25.82  ? 653 PRO B N   1 
ATOM   10091 C  CA  . PRO D 1 660 ? 126.916 121.167 129.405 1.00 25.82  ? 653 PRO B CA  1 
ATOM   10092 C  C   . PRO D 1 660 ? 126.880 121.420 127.906 1.00 25.82  ? 653 PRO B C   1 
ATOM   10093 O  O   . PRO D 1 660 ? 126.446 120.585 127.112 1.00 25.82  ? 653 PRO B O   1 
ATOM   10094 C  CB  . PRO D 1 660 ? 128.281 120.628 129.845 1.00 25.82  ? 653 PRO B CB  1 
ATOM   10095 C  CG  . PRO D 1 660 ? 127.965 119.687 130.949 1.00 25.82  ? 653 PRO B CG  1 
ATOM   10096 C  CD  . PRO D 1 660 ? 126.677 119.038 130.551 1.00 25.82  ? 653 PRO B CD  1 
ATOM   10097 N  N   . PHE D 1 661 ? 127.338 122.612 127.531 1.00 28.36  ? 654 PHE B N   1 
ATOM   10098 C  CA  . PHE D 1 661 ? 127.382 123.009 126.133 1.00 28.36  ? 654 PHE B CA  1 
ATOM   10099 C  C   . PHE D 1 661 ? 128.310 122.102 125.337 1.00 28.36  ? 654 PHE B C   1 
ATOM   10100 O  O   . PHE D 1 661 ? 129.327 121.617 125.839 1.00 28.36  ? 654 PHE B O   1 
ATOM   10101 C  CB  . PHE D 1 661 ? 127.863 124.454 126.009 1.00 28.36  ? 654 PHE B CB  1 
ATOM   10102 C  CG  . PHE D 1 661 ? 126.772 125.472 126.104 1.00 28.36  ? 654 PHE B CG  1 
ATOM   10103 C  CD1 . PHE D 1 661 ? 125.802 125.556 125.125 1.00 28.36  ? 654 PHE B CD1 1 
ATOM   10104 C  CD2 . PHE D 1 661 ? 126.720 126.352 127.169 1.00 28.36  ? 654 PHE B CD2 1 
ATOM   10105 C  CE1 . PHE D 1 661 ? 124.801 126.496 125.208 1.00 28.36  ? 654 PHE B CE1 1 
ATOM   10106 C  CE2 . PHE D 1 661 ? 125.723 127.293 127.255 1.00 28.36  ? 654 PHE B CE2 1 
ATOM   10107 C  CZ  . PHE D 1 661 ? 124.763 127.365 126.274 1.00 28.36  ? 654 PHE B CZ  1 
ATOM   10108 N  N   . SER D 1 662 ? 127.946 121.870 124.076 1.00 32.68  ? 655 SER B N   1 
ATOM   10109 C  CA  . SER D 1 662 ? 128.844 121.173 123.166 1.00 32.68  ? 655 SER B CA  1 
ATOM   10110 C  C   . SER D 1 662 ? 129.967 122.080 122.685 1.00 32.68  ? 655 SER B C   1 
ATOM   10111 O  O   . SER D 1 662 ? 131.048 121.591 122.339 1.00 32.68  ? 655 SER B O   1 
ATOM   10112 C  CB  . SER D 1 662 ? 128.064 120.622 121.973 1.00 32.68  ? 655 SER B CB  1 
ATOM   10113 O  OG  . SER D 1 662 ? 127.252 119.528 122.362 1.00 32.68  ? 655 SER B OG  1 
ATOM   10114 N  N   . PHE D 1 663 ? 129.734 123.389 122.658 1.00 31.45  ? 656 PHE B N   1 
ATOM   10115 C  CA  . PHE D 1 663 ? 130.758 124.332 122.230 1.00 31.45  ? 656 PHE B CA  1 
ATOM   10116 C  C   . PHE D 1 663 ? 131.812 124.498 123.319 1.00 31.45  ? 656 PHE B C   1 
ATOM   10117 O  O   . PHE D 1 663 ? 131.486 124.768 124.479 1.00 31.45  ? 656 PHE B O   1 
ATOM   10118 C  CB  . PHE D 1 663 ? 130.121 125.678 121.893 1.00 31.45  ? 656 PHE B CB  1 
ATOM   10119 C  CG  . PHE D 1 663 ? 131.087 126.691 121.352 1.00 31.45  ? 656 PHE B CG  1 
ATOM   10120 C  CD1 . PHE D 1 663 ? 131.694 127.607 122.193 1.00 31.45  ? 656 PHE B CD1 1 
ATOM   10121 C  CD2 . PHE D 1 663 ? 131.384 126.732 120.003 1.00 31.45  ? 656 PHE B CD2 1 
ATOM   10122 C  CE1 . PHE D 1 663 ? 132.577 128.540 121.697 1.00 31.45  ? 656 PHE B CE1 1 
ATOM   10123 C  CE2 . PHE D 1 663 ? 132.269 127.665 119.503 1.00 31.45  ? 656 PHE B CE2 1 
ATOM   10124 C  CZ  . PHE D 1 663 ? 132.866 128.568 120.352 1.00 31.45  ? 656 PHE B CZ  1 
ATOM   10125 N  N   . LYS D 1 664 ? 133.076 124.346 122.940 1.00 32.29  ? 657 LYS B N   1 
ATOM   10126 C  CA  . LYS D 1 664 ? 134.175 124.441 123.890 1.00 32.29  ? 657 LYS B CA  1 
ATOM   10127 C  C   . LYS D 1 664 ? 134.457 125.901 124.222 1.00 32.29  ? 657 LYS B C   1 
ATOM   10128 O  O   . LYS D 1 664 ? 134.652 126.723 123.321 1.00 32.29  ? 657 LYS B O   1 
ATOM   10129 C  CB  . LYS D 1 664 ? 135.423 123.782 123.313 1.00 32.29  ? 657 LYS B CB  1 
ATOM   10130 C  CG  . LYS D 1 664 ? 135.186 122.415 122.689 1.00 32.29  ? 657 LYS B CG  1 
ATOM   10131 C  CD  . LYS D 1 664 ? 134.619 121.421 123.688 1.00 32.29  ? 657 LYS B CD  1 
ATOM   10132 C  CE  . LYS D 1 664 ? 134.498 120.034 123.074 1.00 32.29  ? 657 LYS B CE  1 
ATOM   10133 N  NZ  . LYS D 1 664 ? 133.763 119.090 123.958 1.00 32.29  ? 657 LYS B NZ  1 
ATOM   10134 N  N   . TRP D 1 665 ? 134.512 126.216 125.519 1.00 28.43  ? 658 TRP B N   1 
ATOM   10135 C  CA  . TRP D 1 665 ? 134.663 127.608 125.935 1.00 28.43  ? 658 TRP B CA  1 
ATOM   10136 C  C   . TRP D 1 665 ? 135.959 128.209 125.410 1.00 28.43  ? 658 TRP B C   1 
ATOM   10137 O  O   . TRP D 1 665 ? 135.975 129.357 124.948 1.00 28.43  ? 658 TRP B O   1 
ATOM   10138 C  CB  . TRP D 1 665 ? 134.586 127.718 127.459 1.00 28.43  ? 658 TRP B CB  1 
ATOM   10139 C  CG  . TRP D 1 665 ? 135.619 126.925 128.204 1.00 28.43  ? 658 TRP B CG  1 
ATOM   10140 C  CD1 . TRP D 1 665 ? 135.487 125.652 128.668 1.00 28.43  ? 658 TRP B CD1 1 
ATOM   10141 C  CD2 . TRP D 1 665 ? 136.925 127.361 128.600 1.00 28.43  ? 658 TRP B CD2 1 
ATOM   10142 N  NE1 . TRP D 1 665 ? 136.633 125.260 129.313 1.00 28.43  ? 658 TRP B NE1 1 
ATOM   10143 C  CE2 . TRP D 1 665 ? 137.532 126.293 129.285 1.00 28.43  ? 658 TRP B CE2 1 
ATOM   10144 C  CE3 . TRP D 1 665 ? 137.644 128.548 128.433 1.00 28.43  ? 658 TRP B CE3 1 
ATOM   10145 C  CZ2 . TRP D 1 665 ? 138.820 126.373 129.803 1.00 28.43  ? 658 TRP B CZ2 1 
ATOM   10146 C  CZ3 . TRP D 1 665 ? 138.925 128.625 128.951 1.00 28.43  ? 658 TRP B CZ3 1 
ATOM   10147 C  CH2 . TRP D 1 665 ? 139.498 127.545 129.625 1.00 28.43  ? 658 TRP B CH2 1 
ATOM   10148 N  N   . TRP D 1 666 ? 137.045 127.436 125.427 1.00 31.35  ? 659 TRP B N   1 
ATOM   10149 C  CA  . TRP D 1 666 ? 138.324 127.953 124.957 1.00 31.35  ? 659 TRP B CA  1 
ATOM   10150 C  C   . TRP D 1 666 ? 138.282 128.352 123.491 1.00 31.35  ? 659 TRP B C   1 
ATOM   10151 O  O   . TRP D 1 666 ? 139.155 129.100 123.041 1.00 31.35  ? 659 TRP B O   1 
ATOM   10152 C  CB  . TRP D 1 666 ? 139.432 126.923 125.177 1.00 31.35  ? 659 TRP B CB  1 
ATOM   10153 C  CG  . TRP D 1 666 ? 139.197 125.608 124.496 1.00 31.35  ? 659 TRP B CG  1 
ATOM   10154 C  CD1 . TRP D 1 666 ? 139.369 125.329 123.172 1.00 31.35  ? 659 TRP B CD1 1 
ATOM   10155 C  CD2 . TRP D 1 666 ? 138.773 124.385 125.111 1.00 31.35  ? 659 TRP B CD2 1 
ATOM   10156 N  NE1 . TRP D 1 666 ? 139.067 124.014 122.924 1.00 31.35  ? 659 TRP B NE1 1 
ATOM   10157 C  CE2 . TRP D 1 666 ? 138.700 123.413 124.098 1.00 31.35  ? 659 TRP B CE2 1 
ATOM   10158 C  CE3 . TRP D 1 666 ? 138.443 124.022 126.417 1.00 31.35  ? 659 TRP B CE3 1 
ATOM   10159 C  CZ2 . TRP D 1 666 ? 138.311 122.103 124.351 1.00 31.35  ? 659 TRP B CZ2 1 
ATOM   10160 C  CZ3 . TRP D 1 666 ? 138.057 122.722 126.663 1.00 31.35  ? 659 TRP B CZ3 1 
ATOM   10161 C  CH2 . TRP D 1 666 ? 137.993 121.779 125.638 1.00 31.35  ? 659 TRP B CH2 1 
ATOM   10162 N  N   . ASN D 1 667 ? 137.291 127.876 122.737 1.00 35.07  ? 660 ASN B N   1 
ATOM   10163 C  CA  . ASN D 1 667 ? 137.192 128.243 121.332 1.00 35.07  ? 660 ASN B CA  1 
ATOM   10164 C  C   . ASN D 1 667 ? 136.644 129.648 121.126 1.00 35.07  ? 660 ASN B C   1 
ATOM   10165 O  O   . ASN D 1 667 ? 136.778 130.190 120.024 1.00 35.07  ? 660 ASN B O   1 
ATOM   10166 C  CB  . ASN D 1 667 ? 136.321 127.234 120.582 1.00 35.07  ? 660 ASN B CB  1 
ATOM   10167 C  CG  . ASN D 1 667 ? 137.095 126.005 120.156 1.00 35.07  ? 660 ASN B CG  1 
ATOM   10168 O  OD1 . ASN D 1 667 ? 138.325 125.994 120.176 1.00 35.07  ? 660 ASN B OD1 1 
ATOM   10169 N  ND2 . ASN D 1 667 ? 136.377 124.962 119.762 1.00 35.07  ? 660 ASN B ND2 1 
ATOM   10170 N  N   . MET D 1 668 ? 136.039 130.249 122.146 1.00 35.69  ? 661 MET B N   1 
ATOM   10171 C  CA  . MET D 1 668 ? 135.544 131.613 122.041 1.00 35.69  ? 661 MET B CA  1 
ATOM   10172 C  C   . MET D 1 668 ? 136.659 132.609 122.329 1.00 35.69  ? 661 MET B C   1 
ATOM   10173 O  O   . MET D 1 668 ? 137.506 132.373 123.193 1.00 35.69  ? 661 MET B O   1 
ATOM   10174 C  CB  . MET D 1 668 ? 134.389 131.849 123.010 1.00 35.69  ? 661 MET B CB  1 
ATOM   10175 C  CG  . MET D 1 668 ? 133.938 133.292 123.061 1.00 35.69  ? 661 MET B CG  1 
ATOM   10176 S  SD  . MET D 1 668 ? 132.338 133.473 123.835 1.00 35.69  ? 661 MET B SD  1 
ATOM   10177 C  CE  . MET D 1 668 ? 132.782 132.951 125.479 1.00 35.69  ? 661 MET B CE  1 
ATOM   10178 N  N   . VAL D 1 669 ? 136.645 133.726 121.610 1.00 40.23  ? 662 VAL B N   1 
ATOM   10179 C  CA  . VAL D 1 669 ? 137.566 134.832 121.859 1.00 40.23  ? 662 VAL B CA  1 
ATOM   10180 C  C   . VAL D 1 669 ? 136.781 135.952 122.548 1.00 40.23  ? 662 VAL B C   1 
ATOM   10181 O  O   . VAL D 1 669 ? 135.840 136.494 121.947 1.00 40.23  ? 662 VAL B O   1 
ATOM   10182 C  CB  . VAL D 1 669 ? 138.246 135.310 120.569 1.00 40.23  ? 662 VAL B CB  1 
ATOM   10183 C  CG1 . VAL D 1 669 ? 137.232 135.731 119.512 1.00 40.23  ? 662 VAL B CG1 1 
ATOM   10184 C  CG2 . VAL D 1 669 ? 139.194 136.454 120.876 1.00 40.23  ? 662 VAL B CG2 1 
ATOM   10185 N  N   . PRO D 1 670 ? 137.090 136.287 123.809 1.00 42.34  ? 663 PRO B N   1 
ATOM   10186 C  CA  . PRO D 1 670 ? 136.433 137.373 124.540 1.00 42.34  ? 663 PRO B CA  1 
ATOM   10187 C  C   . PRO D 1 670 ? 136.850 138.751 124.041 1.00 42.34  ? 663 PRO B C   1 
ATOM   10188 O  O   . PRO D 1 670 ? 136.356 139.774 124.514 1.00 42.34  ? 663 PRO B O   1 
ATOM   10189 C  CB  . PRO D 1 670 ? 136.902 137.163 125.983 1.00 42.34  ? 663 PRO B CB  1 
ATOM   10190 C  CG  . PRO D 1 670 ? 137.384 135.755 126.035 1.00 42.34  ? 663 PRO B CG  1 
ATOM   10191 C  CD  . PRO D 1 670 ? 137.973 135.505 124.687 1.00 42.34  ? 663 PRO B CD  1 
ATOM   10192 O  OXT . PRO D 1 670 ? 137.703 138.874 123.163 1.00 42.34  ? 663 PRO B OXT 1 
HETATM 10193 CA CA  . CA  E 3 .   ? 166.309 154.262 139.093 1.00 51.14  ? 900 CA  A CA  1 
HETATM 10194 CA CA  . CA  F 3 .   ? 146.157 170.021 142.446 1.00 52.60  ? 901 CA  A CA  1 
HETATM 10195 CA CA  . CA  G 3 .   ? 148.760 171.903 140.377 1.00 44.07  ? 902 CA  A CA  1 
HETATM 10196 CA CA  . CA  H 3 .   ? 160.010 156.504 151.822 1.00 46.76  ? 903 CA  A CA  1 
HETATM 10197 CA CA  . CA  I 3 .   ? 140.948 169.590 147.322 1.00 51.56  ? 904 CA  A CA  1 
HETATM 10198 CA CA  . CA  J 3 .   ? 118.689 130.734 139.096 1.00 51.14  ? 900 CA  B CA  1 
HETATM 10199 CA CA  . CA  K 3 .   ? 138.841 114.975 142.448 1.00 52.60  ? 901 CA  B CA  1 
HETATM 10200 CA CA  . CA  L 3 .   ? 136.237 113.092 140.381 1.00 44.07  ? 902 CA  B CA  1 
HETATM 10201 CA CA  . CA  M 3 .   ? 124.992 128.496 151.823 1.00 46.76  ? 903 CA  B CA  1 
HETATM 10202 CA CA  . CA  N 3 .   ? 144.052 115.408 147.322 1.00 51.56  ? 904 CA  B CA  1 
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