data_8R7J
# 
_entry.id   8R7J 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R7J         pdb_00008r7j 10.2210/pdb8r7j/pdb 
WWPDB D_1292134791 ?            ?                   
EMDB  EMD-18977    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-06-11 ? 
2 'EM metadata'     1 0 2025-06-11 ? 
3 FSC               1 0 2025-06-11 ? 
4 'Half map'        1 0 2025-06-11 1 
5 'Half map'        1 0 2025-06-11 2 
6 Image             1 0 2025-06-11 ? 
7 'Primary map'     1 0 2025-06-11 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R7J 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of the human TREX-2 complex' 
_pdbx_database_related.db_id          EMD-18977 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              clemens.plaschka@imp.ac.at 
_pdbx_contact_author.name_first         Clemens 
_pdbx_contact_author.name_last          Plaschka 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6020-9514 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Hohmann, U.'  1 0000-0003-2124-1439 
'Graf, M.'     2 0009-0001-0756-5173 
'Plaschka, C.' 3 0000-0002-6020-9514 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'A molecular switch orchestrates the export of human messenger RNA' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Hohmann, U.'   1 0000-0003-2124-1439 
primary 'Graf, M.'      2 0009-0001-0756-5173 
primary 'Brennecke, J.' 3 0000-0002-5141-0814 
primary 'Plaschka, C.'  4 0000-0002-6020-9514 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Germinal-center associated nuclear protein' 48160.965 1 2.3.1.48,2.3.1.- ? ? ? 
2 polymer man 'PCI domain-containing protein 2'            46095.883 1 ?                ? ? ? 
3 polymer man '26S proteasome complex subunit SEM1'        8284.611  1 ?                ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'GANP,80 kDa MCM3-associated protein,MCM3 acetylating protein,MCM3AP,MCM3 acetyltransferase' 
2 'CSN12-like protein' 
3 
;26S proteasome complex subunit DSS1,Deleted in split hand/split foot protein 1,Split hand/foot deleted protein 1,Split hand/foot malformation type 1 protein
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;SEGLGPCVLSLSTLIGTVAETSKEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCLDMCPEKERYMRETRSQLSVFEVV
PGTDQVDHAAAVKEYSRSSADQEEPLPHELRPLPVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCD
PLTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLSLNKGDIL
REVQQFHPAVRNSSEVKFAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFSQIRKDALRALNFAYTVSTQRSTIFPL
DGVVRMLLFRDCEEATDFLTCHGLTVSDGCVELNRSAFLEPEGLSKTRKSVFITRKLTVSVGEIVNGGPLPPVPRHTPVC
SFNSQNKYIGESLAAELPVSTQR
;
;SEGLGPCVLSLSTLIGTVAETSKEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCLDMCPEKERYMRETRSQLSVFEVV
PGTDQVDHAAAVKEYSRSSADQEEPLPHELRPLPVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCD
PLTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLSLNKGDIL
REVQQFHPAVRNSSEVKFAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFSQIRKDALRALNFAYTVSTQRSTIFPL
DGVVRMLLFRDCEEATDFLTCHGLTVSDGCVELNRSAFLEPEGLSKTRKSVFITRKLTVSVGEIVNGGPLPPVPRHTPVC
SFNSQNKYIGESLAAELPVSTQR
;
A ? 
2 'polypeptide(L)' no no 
;MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEA
YKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGI
EDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC
HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKII
TYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC
;
;MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEA
YKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGI
EDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC
HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKII
TYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC
;
B ? 
3 'polypeptide(L)' no no MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRAELEKHGYKMETS 
MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRAELEKHGYKMETS C ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   GLU n 
1 3   GLY n 
1 4   LEU n 
1 5   GLY n 
1 6   PRO n 
1 7   CYS n 
1 8   VAL n 
1 9   LEU n 
1 10  SER n 
1 11  LEU n 
1 12  SER n 
1 13  THR n 
1 14  LEU n 
1 15  ILE n 
1 16  GLY n 
1 17  THR n 
1 18  VAL n 
1 19  ALA n 
1 20  GLU n 
1 21  THR n 
1 22  SER n 
1 23  LYS n 
1 24  GLU n 
1 25  LYS n 
1 26  TYR n 
1 27  ARG n 
1 28  LEU n 
1 29  LEU n 
1 30  ASP n 
1 31  GLN n 
1 32  ARG n 
1 33  ASP n 
1 34  ARG n 
1 35  ILE n 
1 36  MET n 
1 37  ARG n 
1 38  GLN n 
1 39  ALA n 
1 40  ARG n 
1 41  VAL n 
1 42  LYS n 
1 43  ARG n 
1 44  THR n 
1 45  ASP n 
1 46  LEU n 
1 47  ASP n 
1 48  LYS n 
1 49  ALA n 
1 50  ARG n 
1 51  THR n 
1 52  PHE n 
1 53  VAL n 
1 54  GLY n 
1 55  THR n 
1 56  CYS n 
1 57  LEU n 
1 58  ASP n 
1 59  MET n 
1 60  CYS n 
1 61  PRO n 
1 62  GLU n 
1 63  LYS n 
1 64  GLU n 
1 65  ARG n 
1 66  TYR n 
1 67  MET n 
1 68  ARG n 
1 69  GLU n 
1 70  THR n 
1 71  ARG n 
1 72  SER n 
1 73  GLN n 
1 74  LEU n 
1 75  SER n 
1 76  VAL n 
1 77  PHE n 
1 78  GLU n 
1 79  VAL n 
1 80  VAL n 
1 81  PRO n 
1 82  GLY n 
1 83  THR n 
1 84  ASP n 
1 85  GLN n 
1 86  VAL n 
1 87  ASP n 
1 88  HIS n 
1 89  ALA n 
1 90  ALA n 
1 91  ALA n 
1 92  VAL n 
1 93  LYS n 
1 94  GLU n 
1 95  TYR n 
1 96  SER n 
1 97  ARG n 
1 98  SER n 
1 99  SER n 
1 100 ALA n 
1 101 ASP n 
1 102 GLN n 
1 103 GLU n 
1 104 GLU n 
1 105 PRO n 
1 106 LEU n 
1 107 PRO n 
1 108 HIS n 
1 109 GLU n 
1 110 LEU n 
1 111 ARG n 
1 112 PRO n 
1 113 LEU n 
1 114 PRO n 
1 115 VAL n 
1 116 LEU n 
1 117 SER n 
1 118 ARG n 
1 119 THR n 
1 120 MET n 
1 121 ASP n 
1 122 TYR n 
1 123 LEU n 
1 124 VAL n 
1 125 THR n 
1 126 GLN n 
1 127 ILE n 
1 128 MET n 
1 129 ASP n 
1 130 GLN n 
1 131 LYS n 
1 132 GLU n 
1 133 GLY n 
1 134 SER n 
1 135 LEU n 
1 136 ARG n 
1 137 ASP n 
1 138 TRP n 
1 139 TYR n 
1 140 ASP n 
1 141 PHE n 
1 142 VAL n 
1 143 TRP n 
1 144 ASN n 
1 145 ARG n 
1 146 THR n 
1 147 ARG n 
1 148 GLY n 
1 149 ILE n 
1 150 ARG n 
1 151 LYS n 
1 152 ASP n 
1 153 ILE n 
1 154 THR n 
1 155 GLN n 
1 156 GLN n 
1 157 HIS n 
1 158 LEU n 
1 159 CYS n 
1 160 ASP n 
1 161 PRO n 
1 162 LEU n 
1 163 THR n 
1 164 VAL n 
1 165 SER n 
1 166 LEU n 
1 167 ILE n 
1 168 GLU n 
1 169 LYS n 
1 170 CYS n 
1 171 THR n 
1 172 ARG n 
1 173 PHE n 
1 174 HIS n 
1 175 ILE n 
1 176 HIS n 
1 177 CYS n 
1 178 ALA n 
1 179 HIS n 
1 180 PHE n 
1 181 MET n 
1 182 CYS n 
1 183 GLU n 
1 184 GLU n 
1 185 PRO n 
1 186 MET n 
1 187 SER n 
1 188 SER n 
1 189 PHE n 
1 190 ASP n 
1 191 ALA n 
1 192 LYS n 
1 193 ILE n 
1 194 ASN n 
1 195 ASN n 
1 196 GLU n 
1 197 ASN n 
1 198 MET n 
1 199 THR n 
1 200 LYS n 
1 201 CYS n 
1 202 LEU n 
1 203 GLN n 
1 204 SER n 
1 205 LEU n 
1 206 LYS n 
1 207 GLU n 
1 208 MET n 
1 209 TYR n 
1 210 GLN n 
1 211 ASP n 
1 212 LEU n 
1 213 ARG n 
1 214 ASN n 
1 215 LYS n 
1 216 GLY n 
1 217 VAL n 
1 218 PHE n 
1 219 CYS n 
1 220 ALA n 
1 221 SER n 
1 222 GLU n 
1 223 ALA n 
1 224 GLU n 
1 225 PHE n 
1 226 GLN n 
1 227 GLY n 
1 228 TYR n 
1 229 ASN n 
1 230 VAL n 
1 231 LEU n 
1 232 LEU n 
1 233 SER n 
1 234 LEU n 
1 235 ASN n 
1 236 LYS n 
1 237 GLY n 
1 238 ASP n 
1 239 ILE n 
1 240 LEU n 
1 241 ARG n 
1 242 GLU n 
1 243 VAL n 
1 244 GLN n 
1 245 GLN n 
1 246 PHE n 
1 247 HIS n 
1 248 PRO n 
1 249 ALA n 
1 250 VAL n 
1 251 ARG n 
1 252 ASN n 
1 253 SER n 
1 254 SER n 
1 255 GLU n 
1 256 VAL n 
1 257 LYS n 
1 258 PHE n 
1 259 ALA n 
1 260 VAL n 
1 261 GLN n 
1 262 ALA n 
1 263 PHE n 
1 264 ALA n 
1 265 ALA n 
1 266 LEU n 
1 267 ASN n 
1 268 SER n 
1 269 ASN n 
1 270 ASN n 
1 271 PHE n 
1 272 VAL n 
1 273 ARG n 
1 274 PHE n 
1 275 PHE n 
1 276 LYS n 
1 277 LEU n 
1 278 VAL n 
1 279 GLN n 
1 280 SER n 
1 281 ALA n 
1 282 SER n 
1 283 TYR n 
1 284 LEU n 
1 285 ASN n 
1 286 ALA n 
1 287 CYS n 
1 288 LEU n 
1 289 LEU n 
1 290 HIS n 
1 291 CYS n 
1 292 TYR n 
1 293 PHE n 
1 294 SER n 
1 295 GLN n 
1 296 ILE n 
1 297 ARG n 
1 298 LYS n 
1 299 ASP n 
1 300 ALA n 
1 301 LEU n 
1 302 ARG n 
1 303 ALA n 
1 304 LEU n 
1 305 ASN n 
1 306 PHE n 
1 307 ALA n 
1 308 TYR n 
1 309 THR n 
1 310 VAL n 
1 311 SER n 
1 312 THR n 
1 313 GLN n 
1 314 ARG n 
1 315 SER n 
1 316 THR n 
1 317 ILE n 
1 318 PHE n 
1 319 PRO n 
1 320 LEU n 
1 321 ASP n 
1 322 GLY n 
1 323 VAL n 
1 324 VAL n 
1 325 ARG n 
1 326 MET n 
1 327 LEU n 
1 328 LEU n 
1 329 PHE n 
1 330 ARG n 
1 331 ASP n 
1 332 CYS n 
1 333 GLU n 
1 334 GLU n 
1 335 ALA n 
1 336 THR n 
1 337 ASP n 
1 338 PHE n 
1 339 LEU n 
1 340 THR n 
1 341 CYS n 
1 342 HIS n 
1 343 GLY n 
1 344 LEU n 
1 345 THR n 
1 346 VAL n 
1 347 SER n 
1 348 ASP n 
1 349 GLY n 
1 350 CYS n 
1 351 VAL n 
1 352 GLU n 
1 353 LEU n 
1 354 ASN n 
1 355 ARG n 
1 356 SER n 
1 357 ALA n 
1 358 PHE n 
1 359 LEU n 
1 360 GLU n 
1 361 PRO n 
1 362 GLU n 
1 363 GLY n 
1 364 LEU n 
1 365 SER n 
1 366 LYS n 
1 367 THR n 
1 368 ARG n 
1 369 LYS n 
1 370 SER n 
1 371 VAL n 
1 372 PHE n 
1 373 ILE n 
1 374 THR n 
1 375 ARG n 
1 376 LYS n 
1 377 LEU n 
1 378 THR n 
1 379 VAL n 
1 380 SER n 
1 381 VAL n 
1 382 GLY n 
1 383 GLU n 
1 384 ILE n 
1 385 VAL n 
1 386 ASN n 
1 387 GLY n 
1 388 GLY n 
1 389 PRO n 
1 390 LEU n 
1 391 PRO n 
1 392 PRO n 
1 393 VAL n 
1 394 PRO n 
1 395 ARG n 
1 396 HIS n 
1 397 THR n 
1 398 PRO n 
1 399 VAL n 
1 400 CYS n 
1 401 SER n 
1 402 PHE n 
1 403 ASN n 
1 404 SER n 
1 405 GLN n 
1 406 ASN n 
1 407 LYS n 
1 408 TYR n 
1 409 ILE n 
1 410 GLY n 
1 411 GLU n 
1 412 SER n 
1 413 LEU n 
1 414 ALA n 
1 415 ALA n 
1 416 GLU n 
1 417 LEU n 
1 418 PRO n 
1 419 VAL n 
1 420 SER n 
1 421 THR n 
1 422 GLN n 
1 423 ARG n 
2 1   MET n 
2 2   ALA n 
2 3   HIS n 
2 4   ILE n 
2 5   THR n 
2 6   ILE n 
2 7   ASN n 
2 8   GLN n 
2 9   TYR n 
2 10  LEU n 
2 11  GLN n 
2 12  GLN n 
2 13  VAL n 
2 14  TYR n 
2 15  GLU n 
2 16  ALA n 
2 17  ILE n 
2 18  ASP n 
2 19  SER n 
2 20  ARG n 
2 21  ASP n 
2 22  GLY n 
2 23  ALA n 
2 24  SER n 
2 25  CYS n 
2 26  ALA n 
2 27  GLU n 
2 28  LEU n 
2 29  VAL n 
2 30  SER n 
2 31  PHE n 
2 32  LYS n 
2 33  HIS n 
2 34  PRO n 
2 35  HIS n 
2 36  VAL n 
2 37  ALA n 
2 38  ASN n 
2 39  PRO n 
2 40  ARG n 
2 41  LEU n 
2 42  GLN n 
2 43  MET n 
2 44  ALA n 
2 45  SER n 
2 46  PRO n 
2 47  GLU n 
2 48  GLU n 
2 49  LYS n 
2 50  CYS n 
2 51  GLN n 
2 52  GLN n 
2 53  VAL n 
2 54  LEU n 
2 55  GLU n 
2 56  PRO n 
2 57  PRO n 
2 58  TYR n 
2 59  ASP n 
2 60  GLU n 
2 61  MET n 
2 62  PHE n 
2 63  ALA n 
2 64  ALA n 
2 65  HIS n 
2 66  LEU n 
2 67  ARG n 
2 68  CYS n 
2 69  THR n 
2 70  TYR n 
2 71  ALA n 
2 72  VAL n 
2 73  GLY n 
2 74  ASN n 
2 75  HIS n 
2 76  ASP n 
2 77  PHE n 
2 78  ILE n 
2 79  GLU n 
2 80  ALA n 
2 81  TYR n 
2 82  LYS n 
2 83  CYS n 
2 84  GLN n 
2 85  THR n 
2 86  VAL n 
2 87  ILE n 
2 88  VAL n 
2 89  GLN n 
2 90  SER n 
2 91  PHE n 
2 92  LEU n 
2 93  ARG n 
2 94  ALA n 
2 95  PHE n 
2 96  GLN n 
2 97  ALA n 
2 98  HIS n 
2 99  LYS n 
2 100 GLU n 
2 101 GLU n 
2 102 ASN n 
2 103 TRP n 
2 104 ALA n 
2 105 LEU n 
2 106 PRO n 
2 107 VAL n 
2 108 MET n 
2 109 TYR n 
2 110 ALA n 
2 111 VAL n 
2 112 ALA n 
2 113 LEU n 
2 114 ASP n 
2 115 LEU n 
2 116 ARG n 
2 117 VAL n 
2 118 PHE n 
2 119 ALA n 
2 120 ASN n 
2 121 ASN n 
2 122 ALA n 
2 123 ASP n 
2 124 GLN n 
2 125 GLN n 
2 126 LEU n 
2 127 VAL n 
2 128 LYS n 
2 129 LYS n 
2 130 GLY n 
2 131 LYS n 
2 132 SER n 
2 133 LYS n 
2 134 VAL n 
2 135 GLY n 
2 136 ASP n 
2 137 MET n 
2 138 LEU n 
2 139 GLU n 
2 140 LYS n 
2 141 ALA n 
2 142 ALA n 
2 143 GLU n 
2 144 LEU n 
2 145 LEU n 
2 146 MET n 
2 147 SER n 
2 148 CYS n 
2 149 PHE n 
2 150 ARG n 
2 151 VAL n 
2 152 CYS n 
2 153 ALA n 
2 154 SER n 
2 155 ASP n 
2 156 THR n 
2 157 ARG n 
2 158 ALA n 
2 159 GLY n 
2 160 ILE n 
2 161 GLU n 
2 162 ASP n 
2 163 SER n 
2 164 LYS n 
2 165 LYS n 
2 166 TRP n 
2 167 GLY n 
2 168 MET n 
2 169 LEU n 
2 170 PHE n 
2 171 LEU n 
2 172 VAL n 
2 173 ASN n 
2 174 GLN n 
2 175 LEU n 
2 176 PHE n 
2 177 LYS n 
2 178 ILE n 
2 179 TYR n 
2 180 PHE n 
2 181 LYS n 
2 182 ILE n 
2 183 ASN n 
2 184 LYS n 
2 185 LEU n 
2 186 HIS n 
2 187 LEU n 
2 188 CYS n 
2 189 LYS n 
2 190 PRO n 
2 191 LEU n 
2 192 ILE n 
2 193 ARG n 
2 194 ALA n 
2 195 ILE n 
2 196 ASP n 
2 197 SER n 
2 198 SER n 
2 199 ASN n 
2 200 LEU n 
2 201 LYS n 
2 202 ASP n 
2 203 ASP n 
2 204 TYR n 
2 205 SER n 
2 206 THR n 
2 207 ALA n 
2 208 GLN n 
2 209 ARG n 
2 210 VAL n 
2 211 THR n 
2 212 TYR n 
2 213 LYS n 
2 214 TYR n 
2 215 TYR n 
2 216 VAL n 
2 217 GLY n 
2 218 ARG n 
2 219 LYS n 
2 220 ALA n 
2 221 MET n 
2 222 PHE n 
2 223 ASP n 
2 224 SER n 
2 225 ASP n 
2 226 PHE n 
2 227 LYS n 
2 228 GLN n 
2 229 ALA n 
2 230 GLU n 
2 231 GLU n 
2 232 TYR n 
2 233 LEU n 
2 234 SER n 
2 235 PHE n 
2 236 ALA n 
2 237 PHE n 
2 238 GLU n 
2 239 HIS n 
2 240 CYS n 
2 241 HIS n 
2 242 ARG n 
2 243 SER n 
2 244 SER n 
2 245 GLN n 
2 246 LYS n 
2 247 ASN n 
2 248 LYS n 
2 249 ARG n 
2 250 MET n 
2 251 ILE n 
2 252 LEU n 
2 253 ILE n 
2 254 TYR n 
2 255 LEU n 
2 256 LEU n 
2 257 PRO n 
2 258 VAL n 
2 259 LYS n 
2 260 MET n 
2 261 LEU n 
2 262 LEU n 
2 263 GLY n 
2 264 HIS n 
2 265 MET n 
2 266 PRO n 
2 267 THR n 
2 268 VAL n 
2 269 GLU n 
2 270 LEU n 
2 271 LEU n 
2 272 LYS n 
2 273 LYS n 
2 274 TYR n 
2 275 HIS n 
2 276 LEU n 
2 277 MET n 
2 278 GLN n 
2 279 PHE n 
2 280 ALA n 
2 281 GLU n 
2 282 VAL n 
2 283 THR n 
2 284 ARG n 
2 285 ALA n 
2 286 VAL n 
2 287 SER n 
2 288 GLU n 
2 289 GLY n 
2 290 ASN n 
2 291 LEU n 
2 292 LEU n 
2 293 LEU n 
2 294 LEU n 
2 295 HIS n 
2 296 GLU n 
2 297 ALA n 
2 298 LEU n 
2 299 ALA n 
2 300 LYS n 
2 301 HIS n 
2 302 GLU n 
2 303 ALA n 
2 304 PHE n 
2 305 PHE n 
2 306 ILE n 
2 307 ARG n 
2 308 CYS n 
2 309 GLY n 
2 310 ILE n 
2 311 PHE n 
2 312 LEU n 
2 313 ILE n 
2 314 LEU n 
2 315 GLU n 
2 316 LYS n 
2 317 LEU n 
2 318 LYS n 
2 319 ILE n 
2 320 ILE n 
2 321 THR n 
2 322 TYR n 
2 323 ARG n 
2 324 ASN n 
2 325 LEU n 
2 326 PHE n 
2 327 LYS n 
2 328 LYS n 
2 329 VAL n 
2 330 TYR n 
2 331 LEU n 
2 332 LEU n 
2 333 LEU n 
2 334 LYS n 
2 335 THR n 
2 336 HIS n 
2 337 GLN n 
2 338 LEU n 
2 339 SER n 
2 340 LEU n 
2 341 ASP n 
2 342 ALA n 
2 343 PHE n 
2 344 LEU n 
2 345 VAL n 
2 346 ALA n 
2 347 LEU n 
2 348 LYS n 
2 349 PHE n 
2 350 MET n 
2 351 GLN n 
2 352 VAL n 
2 353 GLU n 
2 354 ASP n 
2 355 VAL n 
2 356 ASP n 
2 357 ILE n 
2 358 ASP n 
2 359 GLU n 
2 360 VAL n 
2 361 GLN n 
2 362 CYS n 
2 363 ILE n 
2 364 LEU n 
2 365 ALA n 
2 366 ASN n 
2 367 LEU n 
2 368 ILE n 
2 369 TYR n 
2 370 MET n 
2 371 GLY n 
2 372 HIS n 
2 373 VAL n 
2 374 LYS n 
2 375 GLY n 
2 376 TYR n 
2 377 ILE n 
2 378 SER n 
2 379 HIS n 
2 380 GLN n 
2 381 HIS n 
2 382 GLN n 
2 383 LYS n 
2 384 LEU n 
2 385 VAL n 
2 386 VAL n 
2 387 SER n 
2 388 LYS n 
2 389 GLN n 
2 390 ASN n 
2 391 PRO n 
2 392 PHE n 
2 393 PRO n 
2 394 PRO n 
2 395 LEU n 
2 396 SER n 
2 397 THR n 
2 398 VAL n 
2 399 CYS n 
3 1   MET n 
3 2   SER n 
3 3   GLU n 
3 4   LYS n 
3 5   LYS n 
3 6   GLN n 
3 7   PRO n 
3 8   VAL n 
3 9   ASP n 
3 10  LEU n 
3 11  GLY n 
3 12  LEU n 
3 13  LEU n 
3 14  GLU n 
3 15  GLU n 
3 16  ASP n 
3 17  ASP n 
3 18  GLU n 
3 19  PHE n 
3 20  GLU n 
3 21  GLU n 
3 22  PHE n 
3 23  PRO n 
3 24  ALA n 
3 25  GLU n 
3 26  ASP n 
3 27  TRP n 
3 28  ALA n 
3 29  GLY n 
3 30  LEU n 
3 31  ASP n 
3 32  GLU n 
3 33  ASP n 
3 34  GLU n 
3 35  ASP n 
3 36  ALA n 
3 37  HIS n 
3 38  VAL n 
3 39  TRP n 
3 40  GLU n 
3 41  ASP n 
3 42  ASN n 
3 43  TRP n 
3 44  ASP n 
3 45  ASP n 
3 46  ASP n 
3 47  ASN n 
3 48  VAL n 
3 49  GLU n 
3 50  ASP n 
3 51  ASP n 
3 52  PHE n 
3 53  SER n 
3 54  ASN n 
3 55  GLN n 
3 56  LEU n 
3 57  ARG n 
3 58  ALA n 
3 59  GLU n 
3 60  LEU n 
3 61  GLU n 
3 62  LYS n 
3 63  HIS n 
3 64  GLY n 
3 65  TYR n 
3 66  LYS n 
3 67  MET n 
3 68  GLU n 
3 69  THR n 
3 70  SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 423 human ? 'MCM3AP, GANP, KIAA0572, MAP80'      ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? 'BL21 DE3 RIL' ?   ? ? ? ? ? ? 'plasmid pOPINB+' ? ? ? 'plasmid 408' ? ? 
2 1 sample 'Biological sequence' 1 399 human ? 'PCID2, HT004'                       ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? 'BL21(DE3)'    RIL ? ? ? ? ? ? 'plasmid pOPINB+' ? ? ? 'plasmid 484' ? ? 
3 1 sample 'Biological sequence' 1 70  human ? 'SEM1, C7orf76, DSS1, SHFDG1, SHFM1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? 'BL21(DE3)'    RIL ? ? ? ? ? ? 'plasmid pOPINB+' ? ? ? 'plasmid 484' ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   582  ?   ?   ?   A . n 
A 1 2   GLU 2   583  ?   ?   ?   A . n 
A 1 3   GLY 3   584  ?   ?   ?   A . n 
A 1 4   LEU 4   585  ?   ?   ?   A . n 
A 1 5   GLY 5   586  ?   ?   ?   A . n 
A 1 6   PRO 6   587  ?   ?   ?   A . n 
A 1 7   CYS 7   588  ?   ?   ?   A . n 
A 1 8   VAL 8   589  ?   ?   ?   A . n 
A 1 9   LEU 9   590  ?   ?   ?   A . n 
A 1 10  SER 10  591  ?   ?   ?   A . n 
A 1 11  LEU 11  592  ?   ?   ?   A . n 
A 1 12  SER 12  593  ?   ?   ?   A . n 
A 1 13  THR 13  594  ?   ?   ?   A . n 
A 1 14  LEU 14  595  ?   ?   ?   A . n 
A 1 15  ILE 15  596  ?   ?   ?   A . n 
A 1 16  GLY 16  597  ?   ?   ?   A . n 
A 1 17  THR 17  598  ?   ?   ?   A . n 
A 1 18  VAL 18  599  ?   ?   ?   A . n 
A 1 19  ALA 19  600  ?   ?   ?   A . n 
A 1 20  GLU 20  601  ?   ?   ?   A . n 
A 1 21  THR 21  602  ?   ?   ?   A . n 
A 1 22  SER 22  603  ?   ?   ?   A . n 
A 1 23  LYS 23  604  ?   ?   ?   A . n 
A 1 24  GLU 24  605  ?   ?   ?   A . n 
A 1 25  LYS 25  606  ?   ?   ?   A . n 
A 1 26  TYR 26  607  ?   ?   ?   A . n 
A 1 27  ARG 27  608  ?   ?   ?   A . n 
A 1 28  LEU 28  609  ?   ?   ?   A . n 
A 1 29  LEU 29  610  ?   ?   ?   A . n 
A 1 30  ASP 30  611  ?   ?   ?   A . n 
A 1 31  GLN 31  612  ?   ?   ?   A . n 
A 1 32  ARG 32  613  ?   ?   ?   A . n 
A 1 33  ASP 33  614  ?   ?   ?   A . n 
A 1 34  ARG 34  615  ?   ?   ?   A . n 
A 1 35  ILE 35  616  ?   ?   ?   A . n 
A 1 36  MET 36  617  ?   ?   ?   A . n 
A 1 37  ARG 37  618  ?   ?   ?   A . n 
A 1 38  GLN 38  619  ?   ?   ?   A . n 
A 1 39  ALA 39  620  ?   ?   ?   A . n 
A 1 40  ARG 40  621  ?   ?   ?   A . n 
A 1 41  VAL 41  622  ?   ?   ?   A . n 
A 1 42  LYS 42  623  ?   ?   ?   A . n 
A 1 43  ARG 43  624  ?   ?   ?   A . n 
A 1 44  THR 44  625  ?   ?   ?   A . n 
A 1 45  ASP 45  626  ?   ?   ?   A . n 
A 1 46  LEU 46  627  ?   ?   ?   A . n 
A 1 47  ASP 47  628  ?   ?   ?   A . n 
A 1 48  LYS 48  629  ?   ?   ?   A . n 
A 1 49  ALA 49  630  ?   ?   ?   A . n 
A 1 50  ARG 50  631  ?   ?   ?   A . n 
A 1 51  THR 51  632  ?   ?   ?   A . n 
A 1 52  PHE 52  633  633 PHE PHE A . n 
A 1 53  VAL 53  634  634 VAL VAL A . n 
A 1 54  GLY 54  635  635 GLY GLY A . n 
A 1 55  THR 55  636  636 THR THR A . n 
A 1 56  CYS 56  637  637 CYS CYS A . n 
A 1 57  LEU 57  638  638 LEU LEU A . n 
A 1 58  ASP 58  639  639 ASP ASP A . n 
A 1 59  MET 59  640  640 MET MET A . n 
A 1 60  CYS 60  641  641 CYS CYS A . n 
A 1 61  PRO 61  642  642 PRO PRO A . n 
A 1 62  GLU 62  643  643 GLU GLU A . n 
A 1 63  LYS 63  644  644 LYS LYS A . n 
A 1 64  GLU 64  645  645 GLU GLU A . n 
A 1 65  ARG 65  646  646 ARG ARG A . n 
A 1 66  TYR 66  647  647 TYR TYR A . n 
A 1 67  MET 67  648  648 MET MET A . n 
A 1 68  ARG 68  649  649 ARG ARG A . n 
A 1 69  GLU 69  650  650 GLU GLU A . n 
A 1 70  THR 70  651  651 THR THR A . n 
A 1 71  ARG 71  652  652 ARG ARG A . n 
A 1 72  SER 72  653  653 SER SER A . n 
A 1 73  GLN 73  654  654 GLN GLN A . n 
A 1 74  LEU 74  655  655 LEU LEU A . n 
A 1 75  SER 75  656  656 SER SER A . n 
A 1 76  VAL 76  657  657 VAL VAL A . n 
A 1 77  PHE 77  658  658 PHE PHE A . n 
A 1 78  GLU 78  659  659 GLU GLU A . n 
A 1 79  VAL 79  660  660 VAL VAL A . n 
A 1 80  VAL 80  661  661 VAL VAL A . n 
A 1 81  PRO 81  662  662 PRO PRO A . n 
A 1 82  GLY 82  663  663 GLY GLY A . n 
A 1 83  THR 83  664  664 THR THR A . n 
A 1 84  ASP 84  665  665 ASP ASP A . n 
A 1 85  GLN 85  666  666 GLN GLN A . n 
A 1 86  VAL 86  667  667 VAL VAL A . n 
A 1 87  ASP 87  668  668 ASP ASP A . n 
A 1 88  HIS 88  669  669 HIS HIS A . n 
A 1 89  ALA 89  670  670 ALA ALA A . n 
A 1 90  ALA 90  671  671 ALA ALA A . n 
A 1 91  ALA 91  672  672 ALA ALA A . n 
A 1 92  VAL 92  673  673 VAL VAL A . n 
A 1 93  LYS 93  674  674 LYS LYS A . n 
A 1 94  GLU 94  675  675 GLU GLU A . n 
A 1 95  TYR 95  676  676 TYR TYR A . n 
A 1 96  SER 96  677  677 SER SER A . n 
A 1 97  ARG 97  678  ?   ?   ?   A . n 
A 1 98  SER 98  679  ?   ?   ?   A . n 
A 1 99  SER 99  680  ?   ?   ?   A . n 
A 1 100 ALA 100 681  ?   ?   ?   A . n 
A 1 101 ASP 101 682  ?   ?   ?   A . n 
A 1 102 GLN 102 683  ?   ?   ?   A . n 
A 1 103 GLU 103 684  684 GLU GLU A . n 
A 1 104 GLU 104 685  685 GLU GLU A . n 
A 1 105 PRO 105 686  686 PRO PRO A . n 
A 1 106 LEU 106 687  687 LEU LEU A . n 
A 1 107 PRO 107 688  688 PRO PRO A . n 
A 1 108 HIS 108 689  689 HIS HIS A . n 
A 1 109 GLU 109 690  690 GLU GLU A . n 
A 1 110 LEU 110 691  691 LEU LEU A . n 
A 1 111 ARG 111 692  692 ARG ARG A . n 
A 1 112 PRO 112 693  693 PRO PRO A . n 
A 1 113 LEU 113 694  694 LEU LEU A . n 
A 1 114 PRO 114 695  695 PRO PRO A . n 
A 1 115 VAL 115 696  696 VAL VAL A . n 
A 1 116 LEU 116 697  697 LEU LEU A . n 
A 1 117 SER 117 698  698 SER SER A . n 
A 1 118 ARG 118 699  699 ARG ARG A . n 
A 1 119 THR 119 700  700 THR THR A . n 
A 1 120 MET 120 701  701 MET MET A . n 
A 1 121 ASP 121 702  702 ASP ASP A . n 
A 1 122 TYR 122 703  703 TYR TYR A . n 
A 1 123 LEU 123 704  704 LEU LEU A . n 
A 1 124 VAL 124 705  705 VAL VAL A . n 
A 1 125 THR 125 706  706 THR THR A . n 
A 1 126 GLN 126 707  707 GLN GLN A . n 
A 1 127 ILE 127 708  708 ILE ILE A . n 
A 1 128 MET 128 709  709 MET MET A . n 
A 1 129 ASP 129 710  710 ASP ASP A . n 
A 1 130 GLN 130 711  711 GLN GLN A . n 
A 1 131 LYS 131 712  712 LYS LYS A . n 
A 1 132 GLU 132 713  713 GLU GLU A . n 
A 1 133 GLY 133 714  714 GLY GLY A . n 
A 1 134 SER 134 715  715 SER SER A . n 
A 1 135 LEU 135 716  716 LEU LEU A . n 
A 1 136 ARG 136 717  717 ARG ARG A . n 
A 1 137 ASP 137 718  718 ASP ASP A . n 
A 1 138 TRP 138 719  719 TRP TRP A . n 
A 1 139 TYR 139 720  720 TYR TYR A . n 
A 1 140 ASP 140 721  721 ASP ASP A . n 
A 1 141 PHE 141 722  722 PHE PHE A . n 
A 1 142 VAL 142 723  723 VAL VAL A . n 
A 1 143 TRP 143 724  724 TRP TRP A . n 
A 1 144 ASN 144 725  725 ASN ASN A . n 
A 1 145 ARG 145 726  726 ARG ARG A . n 
A 1 146 THR 146 727  727 THR THR A . n 
A 1 147 ARG 147 728  728 ARG ARG A . n 
A 1 148 GLY 148 729  729 GLY GLY A . n 
A 1 149 ILE 149 730  730 ILE ILE A . n 
A 1 150 ARG 150 731  731 ARG ARG A . n 
A 1 151 LYS 151 732  732 LYS LYS A . n 
A 1 152 ASP 152 733  733 ASP ASP A . n 
A 1 153 ILE 153 734  734 ILE ILE A . n 
A 1 154 THR 154 735  735 THR THR A . n 
A 1 155 GLN 155 736  736 GLN GLN A . n 
A 1 156 GLN 156 737  737 GLN GLN A . n 
A 1 157 HIS 157 738  738 HIS HIS A . n 
A 1 158 LEU 158 739  739 LEU LEU A . n 
A 1 159 CYS 159 740  740 CYS CYS A . n 
A 1 160 ASP 160 741  741 ASP ASP A . n 
A 1 161 PRO 161 742  742 PRO PRO A . n 
A 1 162 LEU 162 743  743 LEU LEU A . n 
A 1 163 THR 163 744  744 THR THR A . n 
A 1 164 VAL 164 745  745 VAL VAL A . n 
A 1 165 SER 165 746  746 SER SER A . n 
A 1 166 LEU 166 747  747 LEU LEU A . n 
A 1 167 ILE 167 748  748 ILE ILE A . n 
A 1 168 GLU 168 749  749 GLU GLU A . n 
A 1 169 LYS 169 750  750 LYS LYS A . n 
A 1 170 CYS 170 751  751 CYS CYS A . n 
A 1 171 THR 171 752  752 THR THR A . n 
A 1 172 ARG 172 753  753 ARG ARG A . n 
A 1 173 PHE 173 754  754 PHE PHE A . n 
A 1 174 HIS 174 755  755 HIS HIS A . n 
A 1 175 ILE 175 756  756 ILE ILE A . n 
A 1 176 HIS 176 757  757 HIS HIS A . n 
A 1 177 CYS 177 758  758 CYS CYS A . n 
A 1 178 ALA 178 759  759 ALA ALA A . n 
A 1 179 HIS 179 760  760 HIS HIS A . n 
A 1 180 PHE 180 761  761 PHE PHE A . n 
A 1 181 MET 181 762  762 MET MET A . n 
A 1 182 CYS 182 763  763 CYS CYS A . n 
A 1 183 GLU 183 764  764 GLU GLU A . n 
A 1 184 GLU 184 765  765 GLU GLU A . n 
A 1 185 PRO 185 766  766 PRO PRO A . n 
A 1 186 MET 186 767  767 MET MET A . n 
A 1 187 SER 187 768  768 SER SER A . n 
A 1 188 SER 188 769  769 SER SER A . n 
A 1 189 PHE 189 770  770 PHE PHE A . n 
A 1 190 ASP 190 771  771 ASP ASP A . n 
A 1 191 ALA 191 772  772 ALA ALA A . n 
A 1 192 LYS 192 773  773 LYS LYS A . n 
A 1 193 ILE 193 774  774 ILE ILE A . n 
A 1 194 ASN 194 775  775 ASN ASN A . n 
A 1 195 ASN 195 776  776 ASN ASN A . n 
A 1 196 GLU 196 777  777 GLU GLU A . n 
A 1 197 ASN 197 778  778 ASN ASN A . n 
A 1 198 MET 198 779  779 MET MET A . n 
A 1 199 THR 199 780  780 THR THR A . n 
A 1 200 LYS 200 781  781 LYS LYS A . n 
A 1 201 CYS 201 782  782 CYS CYS A . n 
A 1 202 LEU 202 783  783 LEU LEU A . n 
A 1 203 GLN 203 784  784 GLN GLN A . n 
A 1 204 SER 204 785  785 SER SER A . n 
A 1 205 LEU 205 786  786 LEU LEU A . n 
A 1 206 LYS 206 787  787 LYS LYS A . n 
A 1 207 GLU 207 788  788 GLU GLU A . n 
A 1 208 MET 208 789  789 MET MET A . n 
A 1 209 TYR 209 790  790 TYR TYR A . n 
A 1 210 GLN 210 791  791 GLN GLN A . n 
A 1 211 ASP 211 792  792 ASP ASP A . n 
A 1 212 LEU 212 793  793 LEU LEU A . n 
A 1 213 ARG 213 794  794 ARG ARG A . n 
A 1 214 ASN 214 795  795 ASN ASN A . n 
A 1 215 LYS 215 796  796 LYS LYS A . n 
A 1 216 GLY 216 797  797 GLY GLY A . n 
A 1 217 VAL 217 798  798 VAL VAL A . n 
A 1 218 PHE 218 799  799 PHE PHE A . n 
A 1 219 CYS 219 800  800 CYS CYS A . n 
A 1 220 ALA 220 801  801 ALA ALA A . n 
A 1 221 SER 221 802  802 SER SER A . n 
A 1 222 GLU 222 803  803 GLU GLU A . n 
A 1 223 ALA 223 804  804 ALA ALA A . n 
A 1 224 GLU 224 805  805 GLU GLU A . n 
A 1 225 PHE 225 806  806 PHE PHE A . n 
A 1 226 GLN 226 807  807 GLN GLN A . n 
A 1 227 GLY 227 808  808 GLY GLY A . n 
A 1 228 TYR 228 809  809 TYR TYR A . n 
A 1 229 ASN 229 810  810 ASN ASN A . n 
A 1 230 VAL 230 811  811 VAL VAL A . n 
A 1 231 LEU 231 812  812 LEU LEU A . n 
A 1 232 LEU 232 813  813 LEU LEU A . n 
A 1 233 SER 233 814  814 SER SER A . n 
A 1 234 LEU 234 815  815 LEU LEU A . n 
A 1 235 ASN 235 816  816 ASN ASN A . n 
A 1 236 LYS 236 817  817 LYS LYS A . n 
A 1 237 GLY 237 818  818 GLY GLY A . n 
A 1 238 ASP 238 819  819 ASP ASP A . n 
A 1 239 ILE 239 820  820 ILE ILE A . n 
A 1 240 LEU 240 821  821 LEU LEU A . n 
A 1 241 ARG 241 822  822 ARG ARG A . n 
A 1 242 GLU 242 823  823 GLU GLU A . n 
A 1 243 VAL 243 824  824 VAL VAL A . n 
A 1 244 GLN 244 825  825 GLN GLN A . n 
A 1 245 GLN 245 826  826 GLN GLN A . n 
A 1 246 PHE 246 827  827 PHE PHE A . n 
A 1 247 HIS 247 828  828 HIS HIS A . n 
A 1 248 PRO 248 829  829 PRO PRO A . n 
A 1 249 ALA 249 830  830 ALA ALA A . n 
A 1 250 VAL 250 831  831 VAL VAL A . n 
A 1 251 ARG 251 832  832 ARG ARG A . n 
A 1 252 ASN 252 833  833 ASN ASN A . n 
A 1 253 SER 253 834  834 SER SER A . n 
A 1 254 SER 254 835  835 SER SER A . n 
A 1 255 GLU 255 836  836 GLU GLU A . n 
A 1 256 VAL 256 837  837 VAL VAL A . n 
A 1 257 LYS 257 838  838 LYS LYS A . n 
A 1 258 PHE 258 839  839 PHE PHE A . n 
A 1 259 ALA 259 840  840 ALA ALA A . n 
A 1 260 VAL 260 841  841 VAL VAL A . n 
A 1 261 GLN 261 842  842 GLN GLN A . n 
A 1 262 ALA 262 843  843 ALA ALA A . n 
A 1 263 PHE 263 844  844 PHE PHE A . n 
A 1 264 ALA 264 845  845 ALA ALA A . n 
A 1 265 ALA 265 846  846 ALA ALA A . n 
A 1 266 LEU 266 847  847 LEU LEU A . n 
A 1 267 ASN 267 848  848 ASN ASN A . n 
A 1 268 SER 268 849  849 SER SER A . n 
A 1 269 ASN 269 850  850 ASN ASN A . n 
A 1 270 ASN 270 851  851 ASN ASN A . n 
A 1 271 PHE 271 852  852 PHE PHE A . n 
A 1 272 VAL 272 853  853 VAL VAL A . n 
A 1 273 ARG 273 854  854 ARG ARG A . n 
A 1 274 PHE 274 855  855 PHE PHE A . n 
A 1 275 PHE 275 856  856 PHE PHE A . n 
A 1 276 LYS 276 857  857 LYS LYS A . n 
A 1 277 LEU 277 858  858 LEU LEU A . n 
A 1 278 VAL 278 859  859 VAL VAL A . n 
A 1 279 GLN 279 860  860 GLN GLN A . n 
A 1 280 SER 280 861  861 SER SER A . n 
A 1 281 ALA 281 862  862 ALA ALA A . n 
A 1 282 SER 282 863  863 SER SER A . n 
A 1 283 TYR 283 864  864 TYR TYR A . n 
A 1 284 LEU 284 865  865 LEU LEU A . n 
A 1 285 ASN 285 866  866 ASN ASN A . n 
A 1 286 ALA 286 867  867 ALA ALA A . n 
A 1 287 CYS 287 868  868 CYS CYS A . n 
A 1 288 LEU 288 869  869 LEU LEU A . n 
A 1 289 LEU 289 870  870 LEU LEU A . n 
A 1 290 HIS 290 871  871 HIS HIS A . n 
A 1 291 CYS 291 872  872 CYS CYS A . n 
A 1 292 TYR 292 873  873 TYR TYR A . n 
A 1 293 PHE 293 874  874 PHE PHE A . n 
A 1 294 SER 294 875  875 SER SER A . n 
A 1 295 GLN 295 876  876 GLN GLN A . n 
A 1 296 ILE 296 877  877 ILE ILE A . n 
A 1 297 ARG 297 878  878 ARG ARG A . n 
A 1 298 LYS 298 879  879 LYS LYS A . n 
A 1 299 ASP 299 880  880 ASP ASP A . n 
A 1 300 ALA 300 881  881 ALA ALA A . n 
A 1 301 LEU 301 882  882 LEU LEU A . n 
A 1 302 ARG 302 883  883 ARG ARG A . n 
A 1 303 ALA 303 884  884 ALA ALA A . n 
A 1 304 LEU 304 885  885 LEU LEU A . n 
A 1 305 ASN 305 886  886 ASN ASN A . n 
A 1 306 PHE 306 887  887 PHE PHE A . n 
A 1 307 ALA 307 888  888 ALA ALA A . n 
A 1 308 TYR 308 889  889 TYR TYR A . n 
A 1 309 THR 309 890  890 THR THR A . n 
A 1 310 VAL 310 891  891 VAL VAL A . n 
A 1 311 SER 311 892  892 SER SER A . n 
A 1 312 THR 312 893  893 THR THR A . n 
A 1 313 GLN 313 894  894 GLN GLN A . n 
A 1 314 ARG 314 895  895 ARG ARG A . n 
A 1 315 SER 315 896  896 SER SER A . n 
A 1 316 THR 316 897  897 THR THR A . n 
A 1 317 ILE 317 898  898 ILE ILE A . n 
A 1 318 PHE 318 899  899 PHE PHE A . n 
A 1 319 PRO 319 900  900 PRO PRO A . n 
A 1 320 LEU 320 901  901 LEU LEU A . n 
A 1 321 ASP 321 902  902 ASP ASP A . n 
A 1 322 GLY 322 903  903 GLY GLY A . n 
A 1 323 VAL 323 904  904 VAL VAL A . n 
A 1 324 VAL 324 905  905 VAL VAL A . n 
A 1 325 ARG 325 906  906 ARG ARG A . n 
A 1 326 MET 326 907  907 MET MET A . n 
A 1 327 LEU 327 908  908 LEU LEU A . n 
A 1 328 LEU 328 909  909 LEU LEU A . n 
A 1 329 PHE 329 910  910 PHE PHE A . n 
A 1 330 ARG 330 911  911 ARG ARG A . n 
A 1 331 ASP 331 912  912 ASP ASP A . n 
A 1 332 CYS 332 913  913 CYS CYS A . n 
A 1 333 GLU 333 914  914 GLU GLU A . n 
A 1 334 GLU 334 915  915 GLU GLU A . n 
A 1 335 ALA 335 916  916 ALA ALA A . n 
A 1 336 THR 336 917  917 THR THR A . n 
A 1 337 ASP 337 918  918 ASP ASP A . n 
A 1 338 PHE 338 919  919 PHE PHE A . n 
A 1 339 LEU 339 920  920 LEU LEU A . n 
A 1 340 THR 340 921  921 THR THR A . n 
A 1 341 CYS 341 922  922 CYS CYS A . n 
A 1 342 HIS 342 923  923 HIS HIS A . n 
A 1 343 GLY 343 924  924 GLY GLY A . n 
A 1 344 LEU 344 925  925 LEU LEU A . n 
A 1 345 THR 345 926  926 THR THR A . n 
A 1 346 VAL 346 927  927 VAL VAL A . n 
A 1 347 SER 347 928  928 SER SER A . n 
A 1 348 ASP 348 929  929 ASP ASP A . n 
A 1 349 GLY 349 930  930 GLY GLY A . n 
A 1 350 CYS 350 931  931 CYS CYS A . n 
A 1 351 VAL 351 932  932 VAL VAL A . n 
A 1 352 GLU 352 933  933 GLU GLU A . n 
A 1 353 LEU 353 934  934 LEU LEU A . n 
A 1 354 ASN 354 935  935 ASN ASN A . n 
A 1 355 ARG 355 936  936 ARG ARG A . n 
A 1 356 SER 356 937  937 SER SER A . n 
A 1 357 ALA 357 938  938 ALA ALA A . n 
A 1 358 PHE 358 939  939 PHE PHE A . n 
A 1 359 LEU 359 940  940 LEU LEU A . n 
A 1 360 GLU 360 941  941 GLU GLU A . n 
A 1 361 PRO 361 942  942 PRO PRO A . n 
A 1 362 GLU 362 943  943 GLU GLU A . n 
A 1 363 GLY 363 944  944 GLY GLY A . n 
A 1 364 LEU 364 945  945 LEU LEU A . n 
A 1 365 SER 365 946  946 SER SER A . n 
A 1 366 LYS 366 947  947 LYS LYS A . n 
A 1 367 THR 367 948  948 THR THR A . n 
A 1 368 ARG 368 949  949 ARG ARG A . n 
A 1 369 LYS 369 950  950 LYS LYS A . n 
A 1 370 SER 370 951  951 SER SER A . n 
A 1 371 VAL 371 952  952 VAL VAL A . n 
A 1 372 PHE 372 953  953 PHE PHE A . n 
A 1 373 ILE 373 954  954 ILE ILE A . n 
A 1 374 THR 374 955  955 THR THR A . n 
A 1 375 ARG 375 956  956 ARG ARG A . n 
A 1 376 LYS 376 957  957 LYS LYS A . n 
A 1 377 LEU 377 958  958 LEU LEU A . n 
A 1 378 THR 378 959  959 THR THR A . n 
A 1 379 VAL 379 960  960 VAL VAL A . n 
A 1 380 SER 380 961  961 SER SER A . n 
A 1 381 VAL 381 962  962 VAL VAL A . n 
A 1 382 GLY 382 963  963 GLY GLY A . n 
A 1 383 GLU 383 964  964 GLU GLU A . n 
A 1 384 ILE 384 965  965 ILE ILE A . n 
A 1 385 VAL 385 966  966 VAL VAL A . n 
A 1 386 ASN 386 967  967 ASN ASN A . n 
A 1 387 GLY 387 968  968 GLY GLY A . n 
A 1 388 GLY 388 969  969 GLY GLY A . n 
A 1 389 PRO 389 970  970 PRO PRO A . n 
A 1 390 LEU 390 971  971 LEU LEU A . n 
A 1 391 PRO 391 972  972 PRO PRO A . n 
A 1 392 PRO 392 973  973 PRO PRO A . n 
A 1 393 VAL 393 974  974 VAL VAL A . n 
A 1 394 PRO 394 975  975 PRO PRO A . n 
A 1 395 ARG 395 976  976 ARG ARG A . n 
A 1 396 HIS 396 977  ?   ?   ?   A . n 
A 1 397 THR 397 978  ?   ?   ?   A . n 
A 1 398 PRO 398 979  ?   ?   ?   A . n 
A 1 399 VAL 399 980  ?   ?   ?   A . n 
A 1 400 CYS 400 981  ?   ?   ?   A . n 
A 1 401 SER 401 982  ?   ?   ?   A . n 
A 1 402 PHE 402 983  ?   ?   ?   A . n 
A 1 403 ASN 403 984  ?   ?   ?   A . n 
A 1 404 SER 404 985  ?   ?   ?   A . n 
A 1 405 GLN 405 986  ?   ?   ?   A . n 
A 1 406 ASN 406 987  ?   ?   ?   A . n 
A 1 407 LYS 407 988  ?   ?   ?   A . n 
A 1 408 TYR 408 989  ?   ?   ?   A . n 
A 1 409 ILE 409 990  ?   ?   ?   A . n 
A 1 410 GLY 410 991  ?   ?   ?   A . n 
A 1 411 GLU 411 992  ?   ?   ?   A . n 
A 1 412 SER 412 993  ?   ?   ?   A . n 
A 1 413 LEU 413 994  ?   ?   ?   A . n 
A 1 414 ALA 414 995  ?   ?   ?   A . n 
A 1 415 ALA 415 996  ?   ?   ?   A . n 
A 1 416 GLU 416 997  ?   ?   ?   A . n 
A 1 417 LEU 417 998  ?   ?   ?   A . n 
A 1 418 PRO 418 999  ?   ?   ?   A . n 
A 1 419 VAL 419 1000 ?   ?   ?   A . n 
A 1 420 SER 420 1001 ?   ?   ?   A . n 
A 1 421 THR 421 1002 ?   ?   ?   A . n 
A 1 422 GLN 422 1003 ?   ?   ?   A . n 
A 1 423 ARG 423 1004 ?   ?   ?   A . n 
B 2 1   MET 1   1    ?   ?   ?   B . n 
B 2 2   ALA 2   2    ?   ?   ?   B . n 
B 2 3   HIS 3   3    ?   ?   ?   B . n 
B 2 4   ILE 4   4    ?   ?   ?   B . n 
B 2 5   THR 5   5    5   THR THR B . n 
B 2 6   ILE 6   6    6   ILE ILE B . n 
B 2 7   ASN 7   7    7   ASN ASN B . n 
B 2 8   GLN 8   8    8   GLN GLN B . n 
B 2 9   TYR 9   9    9   TYR TYR B . n 
B 2 10  LEU 10  10   10  LEU LEU B . n 
B 2 11  GLN 11  11   11  GLN GLN B . n 
B 2 12  GLN 12  12   12  GLN GLN B . n 
B 2 13  VAL 13  13   13  VAL VAL B . n 
B 2 14  TYR 14  14   14  TYR TYR B . n 
B 2 15  GLU 15  15   15  GLU GLU B . n 
B 2 16  ALA 16  16   16  ALA ALA B . n 
B 2 17  ILE 17  17   17  ILE ILE B . n 
B 2 18  ASP 18  18   18  ASP ASP B . n 
B 2 19  SER 19  19   19  SER SER B . n 
B 2 20  ARG 20  20   20  ARG ARG B . n 
B 2 21  ASP 21  21   21  ASP ASP B . n 
B 2 22  GLY 22  22   22  GLY GLY B . n 
B 2 23  ALA 23  23   23  ALA ALA B . n 
B 2 24  SER 24  24   24  SER SER B . n 
B 2 25  CYS 25  25   25  CYS CYS B . n 
B 2 26  ALA 26  26   26  ALA ALA B . n 
B 2 27  GLU 27  27   27  GLU GLU B . n 
B 2 28  LEU 28  28   28  LEU LEU B . n 
B 2 29  VAL 29  29   29  VAL VAL B . n 
B 2 30  SER 30  30   30  SER SER B . n 
B 2 31  PHE 31  31   31  PHE PHE B . n 
B 2 32  LYS 32  32   32  LYS LYS B . n 
B 2 33  HIS 33  33   33  HIS HIS B . n 
B 2 34  PRO 34  34   34  PRO PRO B . n 
B 2 35  HIS 35  35   35  HIS HIS B . n 
B 2 36  VAL 36  36   ?   ?   ?   B . n 
B 2 37  ALA 37  37   ?   ?   ?   B . n 
B 2 38  ASN 38  38   ?   ?   ?   B . n 
B 2 39  PRO 39  39   ?   ?   ?   B . n 
B 2 40  ARG 40  40   ?   ?   ?   B . n 
B 2 41  LEU 41  41   ?   ?   ?   B . n 
B 2 42  GLN 42  42   ?   ?   ?   B . n 
B 2 43  MET 43  43   ?   ?   ?   B . n 
B 2 44  ALA 44  44   ?   ?   ?   B . n 
B 2 45  SER 45  45   ?   ?   ?   B . n 
B 2 46  PRO 46  46   46  PRO PRO B . n 
B 2 47  GLU 47  47   47  GLU GLU B . n 
B 2 48  GLU 48  48   48  GLU GLU B . n 
B 2 49  LYS 49  49   49  LYS LYS B . n 
B 2 50  CYS 50  50   50  CYS CYS B . n 
B 2 51  GLN 51  51   51  GLN GLN B . n 
B 2 52  GLN 52  52   52  GLN GLN B . n 
B 2 53  VAL 53  53   53  VAL VAL B . n 
B 2 54  LEU 54  54   54  LEU LEU B . n 
B 2 55  GLU 55  55   55  GLU GLU B . n 
B 2 56  PRO 56  56   56  PRO PRO B . n 
B 2 57  PRO 57  57   57  PRO PRO B . n 
B 2 58  TYR 58  58   58  TYR TYR B . n 
B 2 59  ASP 59  59   59  ASP ASP B . n 
B 2 60  GLU 60  60   60  GLU GLU B . n 
B 2 61  MET 61  61   61  MET MET B . n 
B 2 62  PHE 62  62   62  PHE PHE B . n 
B 2 63  ALA 63  63   63  ALA ALA B . n 
B 2 64  ALA 64  64   64  ALA ALA B . n 
B 2 65  HIS 65  65   65  HIS HIS B . n 
B 2 66  LEU 66  66   66  LEU LEU B . n 
B 2 67  ARG 67  67   67  ARG ARG B . n 
B 2 68  CYS 68  68   68  CYS CYS B . n 
B 2 69  THR 69  69   69  THR THR B . n 
B 2 70  TYR 70  70   70  TYR TYR B . n 
B 2 71  ALA 71  71   71  ALA ALA B . n 
B 2 72  VAL 72  72   72  VAL VAL B . n 
B 2 73  GLY 73  73   73  GLY GLY B . n 
B 2 74  ASN 74  74   74  ASN ASN B . n 
B 2 75  HIS 75  75   75  HIS HIS B . n 
B 2 76  ASP 76  76   76  ASP ASP B . n 
B 2 77  PHE 77  77   77  PHE PHE B . n 
B 2 78  ILE 78  78   78  ILE ILE B . n 
B 2 79  GLU 79  79   79  GLU GLU B . n 
B 2 80  ALA 80  80   80  ALA ALA B . n 
B 2 81  TYR 81  81   81  TYR TYR B . n 
B 2 82  LYS 82  82   82  LYS LYS B . n 
B 2 83  CYS 83  83   83  CYS CYS B . n 
B 2 84  GLN 84  84   84  GLN GLN B . n 
B 2 85  THR 85  85   85  THR THR B . n 
B 2 86  VAL 86  86   86  VAL VAL B . n 
B 2 87  ILE 87  87   87  ILE ILE B . n 
B 2 88  VAL 88  88   88  VAL VAL B . n 
B 2 89  GLN 89  89   89  GLN GLN B . n 
B 2 90  SER 90  90   90  SER SER B . n 
B 2 91  PHE 91  91   91  PHE PHE B . n 
B 2 92  LEU 92  92   92  LEU LEU B . n 
B 2 93  ARG 93  93   93  ARG ARG B . n 
B 2 94  ALA 94  94   94  ALA ALA B . n 
B 2 95  PHE 95  95   95  PHE PHE B . n 
B 2 96  GLN 96  96   96  GLN GLN B . n 
B 2 97  ALA 97  97   97  ALA ALA B . n 
B 2 98  HIS 98  98   98  HIS HIS B . n 
B 2 99  LYS 99  99   99  LYS LYS B . n 
B 2 100 GLU 100 100  100 GLU GLU B . n 
B 2 101 GLU 101 101  101 GLU GLU B . n 
B 2 102 ASN 102 102  102 ASN ASN B . n 
B 2 103 TRP 103 103  103 TRP TRP B . n 
B 2 104 ALA 104 104  104 ALA ALA B . n 
B 2 105 LEU 105 105  105 LEU LEU B . n 
B 2 106 PRO 106 106  106 PRO PRO B . n 
B 2 107 VAL 107 107  107 VAL VAL B . n 
B 2 108 MET 108 108  108 MET MET B . n 
B 2 109 TYR 109 109  109 TYR TYR B . n 
B 2 110 ALA 110 110  110 ALA ALA B . n 
B 2 111 VAL 111 111  111 VAL VAL B . n 
B 2 112 ALA 112 112  112 ALA ALA B . n 
B 2 113 LEU 113 113  113 LEU LEU B . n 
B 2 114 ASP 114 114  114 ASP ASP B . n 
B 2 115 LEU 115 115  115 LEU LEU B . n 
B 2 116 ARG 116 116  116 ARG ARG B . n 
B 2 117 VAL 117 117  117 VAL VAL B . n 
B 2 118 PHE 118 118  118 PHE PHE B . n 
B 2 119 ALA 119 119  119 ALA ALA B . n 
B 2 120 ASN 120 120  120 ASN ASN B . n 
B 2 121 ASN 121 121  121 ASN ASN B . n 
B 2 122 ALA 122 122  122 ALA ALA B . n 
B 2 123 ASP 123 123  123 ASP ASP B . n 
B 2 124 GLN 124 124  ?   ?   ?   B . n 
B 2 125 GLN 125 125  ?   ?   ?   B . n 
B 2 126 LEU 126 126  ?   ?   ?   B . n 
B 2 127 VAL 127 127  ?   ?   ?   B . n 
B 2 128 LYS 128 128  ?   ?   ?   B . n 
B 2 129 LYS 129 129  ?   ?   ?   B . n 
B 2 130 GLY 130 130  ?   ?   ?   B . n 
B 2 131 LYS 131 131  ?   ?   ?   B . n 
B 2 132 SER 132 132  ?   ?   ?   B . n 
B 2 133 LYS 133 133  ?   ?   ?   B . n 
B 2 134 VAL 134 134  ?   ?   ?   B . n 
B 2 135 GLY 135 135  135 GLY GLY B . n 
B 2 136 ASP 136 136  136 ASP ASP B . n 
B 2 137 MET 137 137  137 MET MET B . n 
B 2 138 LEU 138 138  138 LEU LEU B . n 
B 2 139 GLU 139 139  139 GLU GLU B . n 
B 2 140 LYS 140 140  140 LYS LYS B . n 
B 2 141 ALA 141 141  141 ALA ALA B . n 
B 2 142 ALA 142 142  142 ALA ALA B . n 
B 2 143 GLU 143 143  143 GLU GLU B . n 
B 2 144 LEU 144 144  144 LEU LEU B . n 
B 2 145 LEU 145 145  145 LEU LEU B . n 
B 2 146 MET 146 146  146 MET MET B . n 
B 2 147 SER 147 147  147 SER SER B . n 
B 2 148 CYS 148 148  148 CYS CYS B . n 
B 2 149 PHE 149 149  149 PHE PHE B . n 
B 2 150 ARG 150 150  150 ARG ARG B . n 
B 2 151 VAL 151 151  151 VAL VAL B . n 
B 2 152 CYS 152 152  152 CYS CYS B . n 
B 2 153 ALA 153 153  153 ALA ALA B . n 
B 2 154 SER 154 154  154 SER SER B . n 
B 2 155 ASP 155 155  155 ASP ASP B . n 
B 2 156 THR 156 156  156 THR THR B . n 
B 2 157 ARG 157 157  ?   ?   ?   B . n 
B 2 158 ALA 158 158  ?   ?   ?   B . n 
B 2 159 GLY 159 159  ?   ?   ?   B . n 
B 2 160 ILE 160 160  160 ILE ILE B . n 
B 2 161 GLU 161 161  161 GLU GLU B . n 
B 2 162 ASP 162 162  162 ASP ASP B . n 
B 2 163 SER 163 163  163 SER SER B . n 
B 2 164 LYS 164 164  164 LYS LYS B . n 
B 2 165 LYS 165 165  165 LYS LYS B . n 
B 2 166 TRP 166 166  166 TRP TRP B . n 
B 2 167 GLY 167 167  167 GLY GLY B . n 
B 2 168 MET 168 168  168 MET MET B . n 
B 2 169 LEU 169 169  169 LEU LEU B . n 
B 2 170 PHE 170 170  170 PHE PHE B . n 
B 2 171 LEU 171 171  171 LEU LEU B . n 
B 2 172 VAL 172 172  172 VAL VAL B . n 
B 2 173 ASN 173 173  173 ASN ASN B . n 
B 2 174 GLN 174 174  174 GLN GLN B . n 
B 2 175 LEU 175 175  175 LEU LEU B . n 
B 2 176 PHE 176 176  176 PHE PHE B . n 
B 2 177 LYS 177 177  177 LYS LYS B . n 
B 2 178 ILE 178 178  178 ILE ILE B . n 
B 2 179 TYR 179 179  179 TYR TYR B . n 
B 2 180 PHE 180 180  180 PHE PHE B . n 
B 2 181 LYS 181 181  181 LYS LYS B . n 
B 2 182 ILE 182 182  182 ILE ILE B . n 
B 2 183 ASN 183 183  183 ASN ASN B . n 
B 2 184 LYS 184 184  184 LYS LYS B . n 
B 2 185 LEU 185 185  185 LEU LEU B . n 
B 2 186 HIS 186 186  186 HIS HIS B . n 
B 2 187 LEU 187 187  187 LEU LEU B . n 
B 2 188 CYS 188 188  188 CYS CYS B . n 
B 2 189 LYS 189 189  189 LYS LYS B . n 
B 2 190 PRO 190 190  190 PRO PRO B . n 
B 2 191 LEU 191 191  191 LEU LEU B . n 
B 2 192 ILE 192 192  192 ILE ILE B . n 
B 2 193 ARG 193 193  193 ARG ARG B . n 
B 2 194 ALA 194 194  194 ALA ALA B . n 
B 2 195 ILE 195 195  195 ILE ILE B . n 
B 2 196 ASP 196 196  196 ASP ASP B . n 
B 2 197 SER 197 197  197 SER SER B . n 
B 2 198 SER 198 198  198 SER SER B . n 
B 2 199 ASN 199 199  199 ASN ASN B . n 
B 2 200 LEU 200 200  200 LEU LEU B . n 
B 2 201 LYS 201 201  201 LYS LYS B . n 
B 2 202 ASP 202 202  202 ASP ASP B . n 
B 2 203 ASP 203 203  203 ASP ASP B . n 
B 2 204 TYR 204 204  204 TYR TYR B . n 
B 2 205 SER 205 205  205 SER SER B . n 
B 2 206 THR 206 206  206 THR THR B . n 
B 2 207 ALA 207 207  207 ALA ALA B . n 
B 2 208 GLN 208 208  208 GLN GLN B . n 
B 2 209 ARG 209 209  209 ARG ARG B . n 
B 2 210 VAL 210 210  210 VAL VAL B . n 
B 2 211 THR 211 211  211 THR THR B . n 
B 2 212 TYR 212 212  212 TYR TYR B . n 
B 2 213 LYS 213 213  213 LYS LYS B . n 
B 2 214 TYR 214 214  214 TYR TYR B . n 
B 2 215 TYR 215 215  215 TYR TYR B . n 
B 2 216 VAL 216 216  216 VAL VAL B . n 
B 2 217 GLY 217 217  217 GLY GLY B . n 
B 2 218 ARG 218 218  218 ARG ARG B . n 
B 2 219 LYS 219 219  219 LYS LYS B . n 
B 2 220 ALA 220 220  220 ALA ALA B . n 
B 2 221 MET 221 221  221 MET MET B . n 
B 2 222 PHE 222 222  222 PHE PHE B . n 
B 2 223 ASP 223 223  223 ASP ASP B . n 
B 2 224 SER 224 224  224 SER SER B . n 
B 2 225 ASP 225 225  225 ASP ASP B . n 
B 2 226 PHE 226 226  226 PHE PHE B . n 
B 2 227 LYS 227 227  227 LYS LYS B . n 
B 2 228 GLN 228 228  228 GLN GLN B . n 
B 2 229 ALA 229 229  229 ALA ALA B . n 
B 2 230 GLU 230 230  230 GLU GLU B . n 
B 2 231 GLU 231 231  231 GLU GLU B . n 
B 2 232 TYR 232 232  232 TYR TYR B . n 
B 2 233 LEU 233 233  233 LEU LEU B . n 
B 2 234 SER 234 234  234 SER SER B . n 
B 2 235 PHE 235 235  235 PHE PHE B . n 
B 2 236 ALA 236 236  236 ALA ALA B . n 
B 2 237 PHE 237 237  237 PHE PHE B . n 
B 2 238 GLU 238 238  238 GLU GLU B . n 
B 2 239 HIS 239 239  239 HIS HIS B . n 
B 2 240 CYS 240 240  240 CYS CYS B . n 
B 2 241 HIS 241 241  241 HIS HIS B . n 
B 2 242 ARG 242 242  242 ARG ARG B . n 
B 2 243 SER 243 243  243 SER SER B . n 
B 2 244 SER 244 244  244 SER SER B . n 
B 2 245 GLN 245 245  245 GLN GLN B . n 
B 2 246 LYS 246 246  246 LYS LYS B . n 
B 2 247 ASN 247 247  247 ASN ASN B . n 
B 2 248 LYS 248 248  248 LYS LYS B . n 
B 2 249 ARG 249 249  249 ARG ARG B . n 
B 2 250 MET 250 250  250 MET MET B . n 
B 2 251 ILE 251 251  251 ILE ILE B . n 
B 2 252 LEU 252 252  252 LEU LEU B . n 
B 2 253 ILE 253 253  253 ILE ILE B . n 
B 2 254 TYR 254 254  254 TYR TYR B . n 
B 2 255 LEU 255 255  255 LEU LEU B . n 
B 2 256 LEU 256 256  256 LEU LEU B . n 
B 2 257 PRO 257 257  257 PRO PRO B . n 
B 2 258 VAL 258 258  258 VAL VAL B . n 
B 2 259 LYS 259 259  259 LYS LYS B . n 
B 2 260 MET 260 260  260 MET MET B . n 
B 2 261 LEU 261 261  261 LEU LEU B . n 
B 2 262 LEU 262 262  262 LEU LEU B . n 
B 2 263 GLY 263 263  263 GLY GLY B . n 
B 2 264 HIS 264 264  264 HIS HIS B . n 
B 2 265 MET 265 265  265 MET MET B . n 
B 2 266 PRO 266 266  266 PRO PRO B . n 
B 2 267 THR 267 267  267 THR THR B . n 
B 2 268 VAL 268 268  268 VAL VAL B . n 
B 2 269 GLU 269 269  269 GLU GLU B . n 
B 2 270 LEU 270 270  270 LEU LEU B . n 
B 2 271 LEU 271 271  271 LEU LEU B . n 
B 2 272 LYS 272 272  272 LYS LYS B . n 
B 2 273 LYS 273 273  273 LYS LYS B . n 
B 2 274 TYR 274 274  274 TYR TYR B . n 
B 2 275 HIS 275 275  275 HIS HIS B . n 
B 2 276 LEU 276 276  276 LEU LEU B . n 
B 2 277 MET 277 277  277 MET MET B . n 
B 2 278 GLN 278 278  278 GLN GLN B . n 
B 2 279 PHE 279 279  279 PHE PHE B . n 
B 2 280 ALA 280 280  280 ALA ALA B . n 
B 2 281 GLU 281 281  281 GLU GLU B . n 
B 2 282 VAL 282 282  282 VAL VAL B . n 
B 2 283 THR 283 283  283 THR THR B . n 
B 2 284 ARG 284 284  284 ARG ARG B . n 
B 2 285 ALA 285 285  285 ALA ALA B . n 
B 2 286 VAL 286 286  286 VAL VAL B . n 
B 2 287 SER 287 287  287 SER SER B . n 
B 2 288 GLU 288 288  288 GLU GLU B . n 
B 2 289 GLY 289 289  ?   ?   ?   B . n 
B 2 290 ASN 290 290  ?   ?   ?   B . n 
B 2 291 LEU 291 291  ?   ?   ?   B . n 
B 2 292 LEU 292 292  292 LEU LEU B . n 
B 2 293 LEU 293 293  293 LEU LEU B . n 
B 2 294 LEU 294 294  294 LEU LEU B . n 
B 2 295 HIS 295 295  295 HIS HIS B . n 
B 2 296 GLU 296 296  296 GLU GLU B . n 
B 2 297 ALA 297 297  297 ALA ALA B . n 
B 2 298 LEU 298 298  298 LEU LEU B . n 
B 2 299 ALA 299 299  299 ALA ALA B . n 
B 2 300 LYS 300 300  300 LYS LYS B . n 
B 2 301 HIS 301 301  301 HIS HIS B . n 
B 2 302 GLU 302 302  302 GLU GLU B . n 
B 2 303 ALA 303 303  303 ALA ALA B . n 
B 2 304 PHE 304 304  304 PHE PHE B . n 
B 2 305 PHE 305 305  305 PHE PHE B . n 
B 2 306 ILE 306 306  306 ILE ILE B . n 
B 2 307 ARG 307 307  307 ARG ARG B . n 
B 2 308 CYS 308 308  308 CYS CYS B . n 
B 2 309 GLY 309 309  309 GLY GLY B . n 
B 2 310 ILE 310 310  310 ILE ILE B . n 
B 2 311 PHE 311 311  311 PHE PHE B . n 
B 2 312 LEU 312 312  312 LEU LEU B . n 
B 2 313 ILE 313 313  313 ILE ILE B . n 
B 2 314 LEU 314 314  314 LEU LEU B . n 
B 2 315 GLU 315 315  315 GLU GLU B . n 
B 2 316 LYS 316 316  316 LYS LYS B . n 
B 2 317 LEU 317 317  317 LEU LEU B . n 
B 2 318 LYS 318 318  318 LYS LYS B . n 
B 2 319 ILE 319 319  319 ILE ILE B . n 
B 2 320 ILE 320 320  320 ILE ILE B . n 
B 2 321 THR 321 321  321 THR THR B . n 
B 2 322 TYR 322 322  322 TYR TYR B . n 
B 2 323 ARG 323 323  323 ARG ARG B . n 
B 2 324 ASN 324 324  324 ASN ASN B . n 
B 2 325 LEU 325 325  325 LEU LEU B . n 
B 2 326 PHE 326 326  326 PHE PHE B . n 
B 2 327 LYS 327 327  327 LYS LYS B . n 
B 2 328 LYS 328 328  328 LYS LYS B . n 
B 2 329 VAL 329 329  329 VAL VAL B . n 
B 2 330 TYR 330 330  330 TYR TYR B . n 
B 2 331 LEU 331 331  331 LEU LEU B . n 
B 2 332 LEU 332 332  332 LEU LEU B . n 
B 2 333 LEU 333 333  333 LEU LEU B . n 
B 2 334 LYS 334 334  334 LYS LYS B . n 
B 2 335 THR 335 335  335 THR THR B . n 
B 2 336 HIS 336 336  336 HIS HIS B . n 
B 2 337 GLN 337 337  337 GLN GLN B . n 
B 2 338 LEU 338 338  338 LEU LEU B . n 
B 2 339 SER 339 339  339 SER SER B . n 
B 2 340 LEU 340 340  340 LEU LEU B . n 
B 2 341 ASP 341 341  341 ASP ASP B . n 
B 2 342 ALA 342 342  342 ALA ALA B . n 
B 2 343 PHE 343 343  343 PHE PHE B . n 
B 2 344 LEU 344 344  344 LEU LEU B . n 
B 2 345 VAL 345 345  345 VAL VAL B . n 
B 2 346 ALA 346 346  346 ALA ALA B . n 
B 2 347 LEU 347 347  347 LEU LEU B . n 
B 2 348 LYS 348 348  348 LYS LYS B . n 
B 2 349 PHE 349 349  349 PHE PHE B . n 
B 2 350 MET 350 350  350 MET MET B . n 
B 2 351 GLN 351 351  351 GLN GLN B . n 
B 2 352 VAL 352 352  352 VAL VAL B . n 
B 2 353 GLU 353 353  353 GLU GLU B . n 
B 2 354 ASP 354 354  354 ASP ASP B . n 
B 2 355 VAL 355 355  355 VAL VAL B . n 
B 2 356 ASP 356 356  356 ASP ASP B . n 
B 2 357 ILE 357 357  357 ILE ILE B . n 
B 2 358 ASP 358 358  358 ASP ASP B . n 
B 2 359 GLU 359 359  359 GLU GLU B . n 
B 2 360 VAL 360 360  360 VAL VAL B . n 
B 2 361 GLN 361 361  361 GLN GLN B . n 
B 2 362 CYS 362 362  362 CYS CYS B . n 
B 2 363 ILE 363 363  363 ILE ILE B . n 
B 2 364 LEU 364 364  364 LEU LEU B . n 
B 2 365 ALA 365 365  365 ALA ALA B . n 
B 2 366 ASN 366 366  366 ASN ASN B . n 
B 2 367 LEU 367 367  367 LEU LEU B . n 
B 2 368 ILE 368 368  368 ILE ILE B . n 
B 2 369 TYR 369 369  369 TYR TYR B . n 
B 2 370 MET 370 370  370 MET MET B . n 
B 2 371 GLY 371 371  371 GLY GLY B . n 
B 2 372 HIS 372 372  372 HIS HIS B . n 
B 2 373 VAL 373 373  373 VAL VAL B . n 
B 2 374 LYS 374 374  374 LYS LYS B . n 
B 2 375 GLY 375 375  375 GLY GLY B . n 
B 2 376 TYR 376 376  376 TYR TYR B . n 
B 2 377 ILE 377 377  377 ILE ILE B . n 
B 2 378 SER 378 378  378 SER SER B . n 
B 2 379 HIS 379 379  379 HIS HIS B . n 
B 2 380 GLN 380 380  380 GLN GLN B . n 
B 2 381 HIS 381 381  381 HIS HIS B . n 
B 2 382 GLN 382 382  382 GLN GLN B . n 
B 2 383 LYS 383 383  383 LYS LYS B . n 
B 2 384 LEU 384 384  384 LEU LEU B . n 
B 2 385 VAL 385 385  385 VAL VAL B . n 
B 2 386 VAL 386 386  386 VAL VAL B . n 
B 2 387 SER 387 387  387 SER SER B . n 
B 2 388 LYS 388 388  388 LYS LYS B . n 
B 2 389 GLN 389 389  389 GLN GLN B . n 
B 2 390 ASN 390 390  390 ASN ASN B . n 
B 2 391 PRO 391 391  391 PRO PRO B . n 
B 2 392 PHE 392 392  392 PHE PHE B . n 
B 2 393 PRO 393 393  393 PRO PRO B . n 
B 2 394 PRO 394 394  394 PRO PRO B . n 
B 2 395 LEU 395 395  395 LEU LEU B . n 
B 2 396 SER 396 396  ?   ?   ?   B . n 
B 2 397 THR 397 397  ?   ?   ?   B . n 
B 2 398 VAL 398 398  ?   ?   ?   B . n 
B 2 399 CYS 399 399  ?   ?   ?   B . n 
C 3 1   MET 1   1    ?   ?   ?   C . n 
C 3 2   SER 2   2    ?   ?   ?   C . n 
C 3 3   GLU 3   3    ?   ?   ?   C . n 
C 3 4   LYS 4   4    ?   ?   ?   C . n 
C 3 5   LYS 5   5    ?   ?   ?   C . n 
C 3 6   GLN 6   6    ?   ?   ?   C . n 
C 3 7   PRO 7   7    ?   ?   ?   C . n 
C 3 8   VAL 8   8    ?   ?   ?   C . n 
C 3 9   ASP 9   9    ?   ?   ?   C . n 
C 3 10  LEU 10  10   ?   ?   ?   C . n 
C 3 11  GLY 11  11   ?   ?   ?   C . n 
C 3 12  LEU 12  12   ?   ?   ?   C . n 
C 3 13  LEU 13  13   ?   ?   ?   C . n 
C 3 14  GLU 14  14   ?   ?   ?   C . n 
C 3 15  GLU 15  15   ?   ?   ?   C . n 
C 3 16  ASP 16  16   ?   ?   ?   C . n 
C 3 17  ASP 17  17   17  ASP ASP C . n 
C 3 18  GLU 18  18   18  GLU GLU C . n 
C 3 19  PHE 19  19   19  PHE PHE C . n 
C 3 20  GLU 20  20   20  GLU GLU C . n 
C 3 21  GLU 21  21   21  GLU GLU C . n 
C 3 22  PHE 22  22   22  PHE PHE C . n 
C 3 23  PRO 23  23   23  PRO PRO C . n 
C 3 24  ALA 24  24   24  ALA ALA C . n 
C 3 25  GLU 25  25   25  GLU GLU C . n 
C 3 26  ASP 26  26   26  ASP ASP C . n 
C 3 27  TRP 27  27   27  TRP TRP C . n 
C 3 28  ALA 28  28   28  ALA ALA C . n 
C 3 29  GLY 29  29   29  GLY GLY C . n 
C 3 30  LEU 30  30   30  LEU LEU C . n 
C 3 31  ASP 31  31   31  ASP ASP C . n 
C 3 32  GLU 32  32   32  GLU GLU C . n 
C 3 33  ASP 33  33   33  ASP ASP C . n 
C 3 34  GLU 34  34   34  GLU GLU C . n 
C 3 35  ASP 35  35   35  ASP ASP C . n 
C 3 36  ALA 36  36   36  ALA ALA C . n 
C 3 37  HIS 37  37   37  HIS HIS C . n 
C 3 38  VAL 38  38   38  VAL VAL C . n 
C 3 39  TRP 39  39   39  TRP TRP C . n 
C 3 40  GLU 40  40   40  GLU GLU C . n 
C 3 41  ASP 41  41   41  ASP ASP C . n 
C 3 42  ASN 42  42   42  ASN ASN C . n 
C 3 43  TRP 43  43   43  TRP TRP C . n 
C 3 44  ASP 44  44   44  ASP ASP C . n 
C 3 45  ASP 45  45   45  ASP ASP C . n 
C 3 46  ASP 46  46   46  ASP ASP C . n 
C 3 47  ASN 47  47   47  ASN ASN C . n 
C 3 48  VAL 48  48   48  VAL VAL C . n 
C 3 49  GLU 49  49   49  GLU GLU C . n 
C 3 50  ASP 50  50   50  ASP ASP C . n 
C 3 51  ASP 51  51   51  ASP ASP C . n 
C 3 52  PHE 52  52   52  PHE PHE C . n 
C 3 53  SER 53  53   53  SER SER C . n 
C 3 54  ASN 54  54   54  ASN ASN C . n 
C 3 55  GLN 55  55   55  GLN GLN C . n 
C 3 56  LEU 56  56   56  LEU LEU C . n 
C 3 57  ARG 57  57   57  ARG ARG C . n 
C 3 58  ALA 58  58   58  ALA ALA C . n 
C 3 59  GLU 59  59   59  GLU GLU C . n 
C 3 60  LEU 60  60   60  LEU LEU C . n 
C 3 61  GLU 61  61   61  GLU GLU C . n 
C 3 62  LYS 62  62   62  LYS LYS C . n 
C 3 63  HIS 63  63   63  HIS HIS C . n 
C 3 64  GLY 64  64   64  GLY GLY C . n 
C 3 65  TYR 65  65   65  TYR TYR C . n 
C 3 66  LYS 66  66   66  LYS LYS C . n 
C 3 67  MET 67  67   67  MET MET C . n 
C 3 68  GLU 68  68   68  GLU GLU C . n 
C 3 69  THR 69  69   ?   ?   ?   C . n 
C 3 70  SER 70  70   ?   ?   ?   C . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLN 711 ? CG  ? A GLN 130 CG  
2  1 Y 1 A GLN 711 ? CD  ? A GLN 130 CD  
3  1 Y 1 A GLN 711 ? OE1 ? A GLN 130 OE1 
4  1 Y 1 A GLN 711 ? NE2 ? A GLN 130 NE2 
5  1 Y 1 A LYS 712 ? CG  ? A LYS 131 CG  
6  1 Y 1 A LYS 712 ? CD  ? A LYS 131 CD  
7  1 Y 1 A LYS 712 ? CE  ? A LYS 131 CE  
8  1 Y 1 A LYS 712 ? NZ  ? A LYS 131 NZ  
9  1 Y 1 A GLU 713 ? CG  ? A GLU 132 CG  
10 1 Y 1 A GLU 713 ? CD  ? A GLU 132 CD  
11 1 Y 1 A GLU 713 ? OE1 ? A GLU 132 OE1 
12 1 Y 1 A GLU 713 ? OE2 ? A GLU 132 OE2 
13 1 Y 1 A GLU 764 ? CG  ? A GLU 183 CG  
14 1 Y 1 A GLU 764 ? CD  ? A GLU 183 CD  
15 1 Y 1 A GLU 764 ? OE1 ? A GLU 183 OE1 
16 1 Y 1 A GLU 764 ? OE2 ? A GLU 183 OE2 
17 1 Y 1 A GLU 765 ? CG  ? A GLU 184 CG  
18 1 Y 1 A GLU 765 ? CD  ? A GLU 184 CD  
19 1 Y 1 A GLU 765 ? OE1 ? A GLU 184 OE1 
20 1 Y 1 A GLU 765 ? OE2 ? A GLU 184 OE2 
21 1 Y 1 A PRO 766 ? CG  ? A PRO 185 CG  
22 1 Y 1 A PRO 766 ? CD  ? A PRO 185 CD  
23 1 Y 1 A MET 767 ? CG  ? A MET 186 CG  
24 1 Y 1 A MET 767 ? SD  ? A MET 186 SD  
25 1 Y 1 A MET 767 ? CE  ? A MET 186 CE  
26 1 Y 1 A GLN 894 ? CG  ? A GLN 313 CG  
27 1 Y 1 A GLN 894 ? CD  ? A GLN 313 CD  
28 1 Y 1 A GLN 894 ? OE1 ? A GLN 313 OE1 
29 1 Y 1 A GLN 894 ? NE2 ? A GLN 313 NE2 
30 1 Y 1 A ARG 895 ? CG  ? A ARG 314 CG  
31 1 Y 1 A ARG 895 ? CD  ? A ARG 314 CD  
32 1 Y 1 A ARG 895 ? NE  ? A ARG 314 NE  
33 1 Y 1 A ARG 895 ? CZ  ? A ARG 314 CZ  
34 1 Y 1 A ARG 895 ? NH1 ? A ARG 314 NH1 
35 1 Y 1 A ARG 895 ? NH2 ? A ARG 314 NH2 
36 1 Y 1 A ASP 929 ? CG  ? A ASP 348 CG  
37 1 Y 1 A ASP 929 ? OD1 ? A ASP 348 OD1 
38 1 Y 1 A ASP 929 ? OD2 ? A ASP 348 OD2 
39 1 Y 1 A CYS 931 ? SG  ? A CYS 350 SG  
40 1 Y 1 A GLU 941 ? CG  ? A GLU 360 CG  
41 1 Y 1 A GLU 941 ? CD  ? A GLU 360 CD  
42 1 Y 1 A GLU 941 ? OE1 ? A GLU 360 OE1 
43 1 Y 1 A GLU 941 ? OE2 ? A GLU 360 OE2 
44 1 Y 1 A GLU 943 ? CG  ? A GLU 362 CG  
45 1 Y 1 A GLU 943 ? CD  ? A GLU 362 CD  
46 1 Y 1 A GLU 943 ? OE1 ? A GLU 362 OE1 
47 1 Y 1 A GLU 943 ? OE2 ? A GLU 362 OE2 
48 1 Y 1 A LEU 945 ? CG  ? A LEU 364 CG  
49 1 Y 1 A LEU 945 ? CD1 ? A LEU 364 CD1 
50 1 Y 1 A LEU 945 ? CD2 ? A LEU 364 CD2 
51 1 Y 1 B HIS 35  ? CG  ? B HIS 35  CG  
52 1 Y 1 B HIS 35  ? ND1 ? B HIS 35  ND1 
53 1 Y 1 B HIS 35  ? CD2 ? B HIS 35  CD2 
54 1 Y 1 B HIS 35  ? CE1 ? B HIS 35  CE1 
55 1 Y 1 B HIS 35  ? NE2 ? B HIS 35  NE2 
56 1 Y 1 B PRO 46  ? CG  ? B PRO 46  CG  
57 1 Y 1 B PRO 46  ? CD  ? B PRO 46  CD  
58 1 Y 1 B LYS 99  ? CG  ? B LYS 99  CG  
59 1 Y 1 B LYS 99  ? CD  ? B LYS 99  CD  
60 1 Y 1 B LYS 99  ? CE  ? B LYS 99  CE  
61 1 Y 1 B LYS 99  ? NZ  ? B LYS 99  NZ  
62 1 Y 1 B GLU 100 ? CG  ? B GLU 100 CG  
63 1 Y 1 B GLU 100 ? CD  ? B GLU 100 CD  
64 1 Y 1 B GLU 100 ? OE1 ? B GLU 100 OE1 
65 1 Y 1 B GLU 100 ? OE2 ? B GLU 100 OE2 
66 1 Y 1 B GLU 101 ? CG  ? B GLU 101 CG  
67 1 Y 1 B GLU 101 ? CD  ? B GLU 101 CD  
68 1 Y 1 B GLU 101 ? OE1 ? B GLU 101 OE1 
69 1 Y 1 B GLU 101 ? OE2 ? B GLU 101 OE2 
70 1 Y 1 B LEU 292 ? CG  ? B LEU 292 CG  
71 1 Y 1 B LEU 292 ? CD1 ? B LEU 292 CD1 
72 1 Y 1 B LEU 292 ? CD2 ? B LEU 292 CD2 
73 1 Y 1 C ASP 17  ? CG  ? C ASP 17  CG  
74 1 Y 1 C ASP 17  ? OD1 ? C ASP 17  OD1 
75 1 Y 1 C ASP 17  ? OD2 ? C ASP 17  OD2 
76 1 Y 1 C LYS 66  ? CG  ? C LYS 66  CG  
77 1 Y 1 C LYS 66  ? CD  ? C LYS 66  CD  
78 1 Y 1 C LYS 66  ? CE  ? C LYS 66  CE  
79 1 Y 1 C LYS 66  ? NZ  ? C LYS 66  NZ  
80 1 Y 1 C MET 67  ? CG  ? C MET 67  CG  
81 1 Y 1 C MET 67  ? SD  ? C MET 67  SD  
82 1 Y 1 C MET 67  ? CE  ? C MET 67  CE  
83 1 Y 1 C GLU 68  ? CG  ? C GLU 68  CG  
84 1 Y 1 C GLU 68  ? CD  ? C GLU 68  CD  
85 1 Y 1 C GLU 68  ? OE1 ? C GLU 68  OE1 
86 1 Y 1 C GLU 68  ? OE2 ? C GLU 68  OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R7J 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R7J 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R7J 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8R7J 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.006 ? 6173 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 1.302 ? 8343 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 6.702 ? 810  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.063 ? 926  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.009 ? 1071 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8R7J 
_struct.title                        'Cryo-EM structure of the human TREX-2 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R7J 
_struct_keywords.text            'mRNA export, nuclear pore basket, GENE REGULATION' 
_struct_keywords.pdbx_keywords   'GENE REGULATION' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GANP_HUMAN  O60318 ? 1 
;SEGLGPCVLSLSTLIGTVAETSKEKYRLLDQRDRIMRQARVKRTDLDKARTFVGTCLDMCPEKERYMRETRSQLSVFEVV
PGTDQVDHAAAVKEYSRSSADQEEPLPHELRPLPVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCD
PLTVSLIEKCTRFHIHCAHFMCEEPMSSFDAKINNENMTKCLQSLKEMYQDLRNKGVFCASEAEFQGYNVLLSLNKGDIL
REVQQFHPAVRNSSEVKFAVQAFAALNSNNFVRFFKLVQSASYLNACLLHCYFSQIRKDALRALNFAYTVSTQRSTIFPL
DGVVRMLLFRDCEEATDFLTCHGLTVSDGCVELNRSAFLEPEGLSKTRKSVFITRKLTVSVGEIVNGGPLPPVPRHTPVC
SFNSQNKYIGESLAAELPVSTQR
;
582 
2 UNP PCID2_HUMAN Q5JVF3 ? 2 
;MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEA
YKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFANNADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGI
EDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC
HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAKHEAFFIRCGIFLILEKLKII
TYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC
;
1   
3 UNP SEM1_HUMAN  P60896 ? 3 MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRAELEKHGYKMETS 1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8R7J A 1 ? 423 ? O60318 582 ? 1004 ? 582 1004 
2 2 8R7J B 1 ? 399 ? Q5JVF3 1   ? 399  ? 1   399  
3 3 8R7J C 1 ? 70  ? P60896 1   ? 70   ? 1   70   
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 63  ? SER A 72  ? LYS A 644 SER A 653 1 ? 10 
HELX_P HELX_P2  AA2 PRO A 112 ? GLN A 126 ? PRO A 693 GLN A 707 1 ? 15 
HELX_P HELX_P3  AA3 LEU A 135 ? GLN A 155 ? LEU A 716 GLN A 736 1 ? 21 
HELX_P HELX_P4  AA4 ASP A 160 ? MET A 181 ? ASP A 741 MET A 762 1 ? 22 
HELX_P HELX_P5  AA5 ASP A 190 ? GLY A 216 ? ASP A 771 GLY A 797 1 ? 27 
HELX_P HELX_P6  AA6 SER A 221 ? SER A 233 ? SER A 802 SER A 814 1 ? 13 
HELX_P HELX_P7  AA7 ASP A 238 ? GLN A 244 ? ASP A 819 GLN A 825 1 ? 7  
HELX_P HELX_P8  AA8 HIS A 247 ? ASN A 252 ? HIS A 828 ASN A 833 1 ? 6  
HELX_P HELX_P9  AA9 GLU A 255 ? SER A 268 ? GLU A 836 SER A 849 1 ? 14 
HELX_P HELX_P10 AB1 PHE A 271 ? GLN A 279 ? PHE A 852 GLN A 860 1 ? 9  
HELX_P HELX_P11 AB2 SER A 282 ? LEU A 289 ? SER A 863 LEU A 870 1 ? 8  
HELX_P HELX_P12 AB3 TYR A 292 ? ARG A 302 ? TYR A 873 ARG A 883 1 ? 11 
HELX_P HELX_P13 AB4 GLY A 322 ? LEU A 327 ? GLY A 903 LEU A 908 1 ? 6  
HELX_P HELX_P14 AB5 ASP A 331 ? GLY A 343 ? ASP A 912 GLY A 924 1 ? 13 
HELX_P HELX_P15 AB6 VAL A 381 ? GLY A 387 ? VAL A 962 GLY A 968 1 ? 7  
HELX_P HELX_P16 AB7 ILE B 6   ? SER B 19  ? ILE B 6   SER B 19  1 ? 14 
HELX_P HELX_P17 AB8 ALA B 23  ? LEU B 28  ? ALA B 23  LEU B 28  1 ? 6  
HELX_P HELX_P18 AB9 GLU B 47  ? LEU B 54  ? GLU B 47  LEU B 54  1 ? 8  
HELX_P HELX_P19 AC1 GLU B 55  ? ASN B 74  ? GLU B 55  ASN B 74  1 ? 20 
HELX_P HELX_P20 AC2 PHE B 77  ? ALA B 97  ? PHE B 77  ALA B 97  1 ? 21 
HELX_P HELX_P21 AC3 ALA B 104 ? LEU B 113 ? ALA B 104 LEU B 113 1 ? 10 
HELX_P HELX_P22 AC4 LEU B 113 ? ASN B 121 ? LEU B 113 ASN B 121 1 ? 9  
HELX_P HELX_P23 AC5 ASP B 136 ? ALA B 153 ? ASP B 136 ALA B 153 1 ? 18 
HELX_P HELX_P24 AC6 GLY B 167 ? ASN B 183 ? GLY B 167 ASN B 183 1 ? 17 
HELX_P HELX_P25 AC7 CYS B 188 ? SER B 197 ? CYS B 188 SER B 197 1 ? 10 
HELX_P HELX_P26 AC8 SER B 205 ? PHE B 222 ? SER B 205 PHE B 222 1 ? 18 
HELX_P HELX_P27 AC9 ASP B 225 ? HIS B 239 ? ASP B 225 HIS B 239 1 ? 15 
HELX_P HELX_P28 AD1 LYS B 246 ? GLY B 263 ? LYS B 246 GLY B 263 1 ? 18 
HELX_P HELX_P29 AD2 THR B 267 ? TYR B 274 ? THR B 267 TYR B 274 1 ? 8  
HELX_P HELX_P30 AD3 PHE B 279 ? GLU B 288 ? PHE B 279 GLU B 288 1 ? 10 
HELX_P HELX_P31 AD4 LEU B 293 ? HIS B 301 ? LEU B 293 HIS B 301 1 ? 9  
HELX_P HELX_P32 AD5 ILE B 310 ? GLU B 315 ? ILE B 310 GLU B 315 1 ? 6  
HELX_P HELX_P33 AD6 LEU B 317 ? LYS B 334 ? LEU B 317 LYS B 334 1 ? 18 
HELX_P HELX_P34 AD7 LEU B 340 ? PHE B 349 ? LEU B 340 PHE B 349 1 ? 10 
HELX_P HELX_P35 AD8 ASP B 356 ? MET B 370 ? ASP B 356 MET B 370 1 ? 15 
HELX_P HELX_P36 AD9 ASP C 50  ? LEU C 60  ? ASP C 50  LEU C 60  1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           B 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            68 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            83 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            B 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             68 
_struct_conn.ptnr2_auth_asym_id            B 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             83 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.026 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      B 
_pdbx_modification_feature.label_seq_id                       68 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     B 
_pdbx_modification_feature.modified_residue_label_seq_id      83 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       B 
_pdbx_modification_feature.auth_seq_id                        68 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      B 
_pdbx_modification_feature.modified_residue_auth_seq_id       83 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 318 ? PRO A 319 ? PHE A 899 PRO A 900 
AA1 2 CYS A 350 ? VAL A 351 ? CYS A 931 VAL A 932 
AA2 1 GLN B 337 ? SER B 339 ? GLN B 337 SER B 339 
AA2 2 LYS B 383 ? VAL B 385 ? LYS B 383 VAL B 385 
AA2 3 TYR B 376 ? ILE B 377 ? TYR B 376 ILE B 377 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 318 ? N PHE A 899 O VAL A 351 ? O VAL A 932 
AA2 1 2 N LEU B 338 ? N LEU B 338 O LEU B 384 ? O LEU B 384 
AA2 2 3 O VAL B 385 ? O VAL B 385 N TYR B 376 ? N TYR B 376 
# 
_pdbx_entry_details.entry_id                   8R7J 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA A LEU 687 ? ? CB A LEU 687 ? ? CG  A LEU 687 ? ? 132.63 115.30 17.33 2.30 N 
2 1 CA B LEU 185 ? ? CB B LEU 185 ? ? CG  B LEU 185 ? ? 130.89 115.30 15.59 2.30 N 
3 1 CB B MET 221 ? ? CG B MET 221 ? ? SD  B MET 221 ? ? 131.78 112.40 19.38 3.00 N 
4 1 CB B ASP 223 ? ? CG B ASP 223 ? ? OD1 B ASP 223 ? ? 126.33 118.30 8.03  0.90 N 
5 1 CA B CYS 240 ? ? CB B CYS 240 ? ? SG  B CYS 240 ? ? 124.61 114.20 10.41 1.10 N 
6 1 C  B HIS 264 ? ? N  B MET 265 ? ? CA  B MET 265 ? ? 138.05 121.70 16.35 2.50 Y 
7 1 CB C ASP 51  ? ? CG C ASP 51  ? ? OD1 C ASP 51  ? ? 125.03 118.30 6.73  0.90 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 THR A 664 ? ? 45.26   -150.66 
2  1 ASP A 665 ? ? 61.95   -78.57  
3  1 LEU A 687 ? ? 71.55   161.20  
4  1 GLU A 690 ? ? 50.05   19.48   
5  1 GLN A 707 ? ? -132.48 -37.40  
6  1 MET A 767 ? ? 28.65   -61.44  
7  1 ASP A 771 ? ? 57.65   73.17   
8  1 SER A 892 ? ? -122.85 -70.79  
9  1 THR A 893 ? ? -151.54 -0.31   
10 1 ASP A 929 ? ? 62.99   -121.29 
11 1 VAL A 952 ? ? 66.46   -56.05  
12 1 VAL A 974 ? ? 52.33   76.94   
13 1 ARG B 20  ? ? 38.59   57.94   
14 1 GLU B 100 ? ? 61.67   67.81   
15 1 LEU B 115 ? ? -97.49  59.64   
16 1 ARG B 116 ? ? -134.26 -39.61  
17 1 ALA B 122 ? ? -141.62 22.16   
18 1 LEU B 185 ? ? -95.18  56.55   
19 1 ASP B 223 ? ? 34.40   42.77   
20 1 CYS B 240 ? ? 88.25   154.35  
21 1 GLN B 245 ? ? -95.20  51.18   
22 1 LYS B 334 ? ? 63.76   63.54   
23 1 ASP B 354 ? ? 60.84   64.42   
24 1 ALA C 36  ? ? 61.71   -74.51  
25 1 VAL C 38  ? ? -126.39 -59.12  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8R7J 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8R7J 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.5 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               316490 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.9 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Human TREX-2 complex middle domain' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        8R7J 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8R7J 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   281 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8R7J 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A SER 582  ? A SER 1   
2   1 Y 1 A GLU 583  ? A GLU 2   
3   1 Y 1 A GLY 584  ? A GLY 3   
4   1 Y 1 A LEU 585  ? A LEU 4   
5   1 Y 1 A GLY 586  ? A GLY 5   
6   1 Y 1 A PRO 587  ? A PRO 6   
7   1 Y 1 A CYS 588  ? A CYS 7   
8   1 Y 1 A VAL 589  ? A VAL 8   
9   1 Y 1 A LEU 590  ? A LEU 9   
10  1 Y 1 A SER 591  ? A SER 10  
11  1 Y 1 A LEU 592  ? A LEU 11  
12  1 Y 1 A SER 593  ? A SER 12  
13  1 Y 1 A THR 594  ? A THR 13  
14  1 Y 1 A LEU 595  ? A LEU 14  
15  1 Y 1 A ILE 596  ? A ILE 15  
16  1 Y 1 A GLY 597  ? A GLY 16  
17  1 Y 1 A THR 598  ? A THR 17  
18  1 Y 1 A VAL 599  ? A VAL 18  
19  1 Y 1 A ALA 600  ? A ALA 19  
20  1 Y 1 A GLU 601  ? A GLU 20  
21  1 Y 1 A THR 602  ? A THR 21  
22  1 Y 1 A SER 603  ? A SER 22  
23  1 Y 1 A LYS 604  ? A LYS 23  
24  1 Y 1 A GLU 605  ? A GLU 24  
25  1 Y 1 A LYS 606  ? A LYS 25  
26  1 Y 1 A TYR 607  ? A TYR 26  
27  1 Y 1 A ARG 608  ? A ARG 27  
28  1 Y 1 A LEU 609  ? A LEU 28  
29  1 Y 1 A LEU 610  ? A LEU 29  
30  1 Y 1 A ASP 611  ? A ASP 30  
31  1 Y 1 A GLN 612  ? A GLN 31  
32  1 Y 1 A ARG 613  ? A ARG 32  
33  1 Y 1 A ASP 614  ? A ASP 33  
34  1 Y 1 A ARG 615  ? A ARG 34  
35  1 Y 1 A ILE 616  ? A ILE 35  
36  1 Y 1 A MET 617  ? A MET 36  
37  1 Y 1 A ARG 618  ? A ARG 37  
38  1 Y 1 A GLN 619  ? A GLN 38  
39  1 Y 1 A ALA 620  ? A ALA 39  
40  1 Y 1 A ARG 621  ? A ARG 40  
41  1 Y 1 A VAL 622  ? A VAL 41  
42  1 Y 1 A LYS 623  ? A LYS 42  
43  1 Y 1 A ARG 624  ? A ARG 43  
44  1 Y 1 A THR 625  ? A THR 44  
45  1 Y 1 A ASP 626  ? A ASP 45  
46  1 Y 1 A LEU 627  ? A LEU 46  
47  1 Y 1 A ASP 628  ? A ASP 47  
48  1 Y 1 A LYS 629  ? A LYS 48  
49  1 Y 1 A ALA 630  ? A ALA 49  
50  1 Y 1 A ARG 631  ? A ARG 50  
51  1 Y 1 A THR 632  ? A THR 51  
52  1 Y 1 A ARG 678  ? A ARG 97  
53  1 Y 1 A SER 679  ? A SER 98  
54  1 Y 1 A SER 680  ? A SER 99  
55  1 Y 1 A ALA 681  ? A ALA 100 
56  1 Y 1 A ASP 682  ? A ASP 101 
57  1 Y 1 A GLN 683  ? A GLN 102 
58  1 Y 1 A HIS 977  ? A HIS 396 
59  1 Y 1 A THR 978  ? A THR 397 
60  1 Y 1 A PRO 979  ? A PRO 398 
61  1 Y 1 A VAL 980  ? A VAL 399 
62  1 Y 1 A CYS 981  ? A CYS 400 
63  1 Y 1 A SER 982  ? A SER 401 
64  1 Y 1 A PHE 983  ? A PHE 402 
65  1 Y 1 A ASN 984  ? A ASN 403 
66  1 Y 1 A SER 985  ? A SER 404 
67  1 Y 1 A GLN 986  ? A GLN 405 
68  1 Y 1 A ASN 987  ? A ASN 406 
69  1 Y 1 A LYS 988  ? A LYS 407 
70  1 Y 1 A TYR 989  ? A TYR 408 
71  1 Y 1 A ILE 990  ? A ILE 409 
72  1 Y 1 A GLY 991  ? A GLY 410 
73  1 Y 1 A GLU 992  ? A GLU 411 
74  1 Y 1 A SER 993  ? A SER 412 
75  1 Y 1 A LEU 994  ? A LEU 413 
76  1 Y 1 A ALA 995  ? A ALA 414 
77  1 Y 1 A ALA 996  ? A ALA 415 
78  1 Y 1 A GLU 997  ? A GLU 416 
79  1 Y 1 A LEU 998  ? A LEU 417 
80  1 Y 1 A PRO 999  ? A PRO 418 
81  1 Y 1 A VAL 1000 ? A VAL 419 
82  1 Y 1 A SER 1001 ? A SER 420 
83  1 Y 1 A THR 1002 ? A THR 421 
84  1 Y 1 A GLN 1003 ? A GLN 422 
85  1 Y 1 A ARG 1004 ? A ARG 423 
86  1 Y 1 B MET 1    ? B MET 1   
87  1 Y 1 B ALA 2    ? B ALA 2   
88  1 Y 1 B HIS 3    ? B HIS 3   
89  1 Y 1 B ILE 4    ? B ILE 4   
90  1 Y 1 B VAL 36   ? B VAL 36  
91  1 Y 1 B ALA 37   ? B ALA 37  
92  1 Y 1 B ASN 38   ? B ASN 38  
93  1 Y 1 B PRO 39   ? B PRO 39  
94  1 Y 1 B ARG 40   ? B ARG 40  
95  1 Y 1 B LEU 41   ? B LEU 41  
96  1 Y 1 B GLN 42   ? B GLN 42  
97  1 Y 1 B MET 43   ? B MET 43  
98  1 Y 1 B ALA 44   ? B ALA 44  
99  1 Y 1 B SER 45   ? B SER 45  
100 1 Y 1 B GLN 124  ? B GLN 124 
101 1 Y 1 B GLN 125  ? B GLN 125 
102 1 Y 1 B LEU 126  ? B LEU 126 
103 1 Y 1 B VAL 127  ? B VAL 127 
104 1 Y 1 B LYS 128  ? B LYS 128 
105 1 Y 1 B LYS 129  ? B LYS 129 
106 1 Y 1 B GLY 130  ? B GLY 130 
107 1 Y 1 B LYS 131  ? B LYS 131 
108 1 Y 1 B SER 132  ? B SER 132 
109 1 Y 1 B LYS 133  ? B LYS 133 
110 1 Y 1 B VAL 134  ? B VAL 134 
111 1 Y 1 B ARG 157  ? B ARG 157 
112 1 Y 1 B ALA 158  ? B ALA 158 
113 1 Y 1 B GLY 159  ? B GLY 159 
114 1 Y 1 B GLY 289  ? B GLY 289 
115 1 Y 1 B ASN 290  ? B ASN 290 
116 1 Y 1 B LEU 291  ? B LEU 291 
117 1 Y 1 B SER 396  ? B SER 396 
118 1 Y 1 B THR 397  ? B THR 397 
119 1 Y 1 B VAL 398  ? B VAL 398 
120 1 Y 1 B CYS 399  ? B CYS 399 
121 1 Y 1 C MET 1    ? C MET 1   
122 1 Y 1 C SER 2    ? C SER 2   
123 1 Y 1 C GLU 3    ? C GLU 3   
124 1 Y 1 C LYS 4    ? C LYS 4   
125 1 Y 1 C LYS 5    ? C LYS 5   
126 1 Y 1 C GLN 6    ? C GLN 6   
127 1 Y 1 C PRO 7    ? C PRO 7   
128 1 Y 1 C VAL 8    ? C VAL 8   
129 1 Y 1 C ASP 9    ? C ASP 9   
130 1 Y 1 C LEU 10   ? C LEU 10  
131 1 Y 1 C GLY 11   ? C GLY 11  
132 1 Y 1 C LEU 12   ? C LEU 12  
133 1 Y 1 C LEU 13   ? C LEU 13  
134 1 Y 1 C GLU 14   ? C GLU 14  
135 1 Y 1 C GLU 15   ? C GLU 15  
136 1 Y 1 C ASP 16   ? C ASP 16  
137 1 Y 1 C THR 69   ? C THR 69  
138 1 Y 1 C SER 70   ? C SER 70  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-25 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           8R7J 
_em_admin.last_update        2025-06-11 
_em_admin.map_release_date   2025-06-11 
_em_admin.title              'Cryo-EM structure of the human TREX-2 complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                KILODALTONS/NANOMETER 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          469008 
_em_entity_assembly_recombinant.organism             'Escherichia coli BL21(DE3)' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?            
MASKING                    ? 4  ? ? ? ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?            
'MODEL FITTING'            ? 8  ? ? ? ?      ?            
OTHER                      ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           0.7 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'European Research Council (ERC)'                      'European Union' 949081         1 
'H2020 Marie Curie Actions of the European Commission' 'European Union' 896416         2 
'European Molecular Biology Organization (EMBO)'       'European Union' ALTF_1175-2019 3 
# 
_atom_sites.entry_id                    8R7J 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . PHE A 1 52  ? 121.561 147.992 103.709 1.00 146.00 ? 633 PHE A N   1 
ATOM 2    C CA  . PHE A 1 52  ? 121.897 149.298 104.262 1.00 146.00 ? 633 PHE A CA  1 
ATOM 3    C C   . PHE A 1 52  ? 122.339 149.163 105.716 1.00 146.00 ? 633 PHE A C   1 
ATOM 4    O O   . PHE A 1 52  ? 121.648 148.550 106.529 1.00 146.00 ? 633 PHE A O   1 
ATOM 5    C CB  . PHE A 1 52  ? 120.704 150.251 104.148 1.00 146.00 ? 633 PHE A CB  1 
ATOM 6    C CG  . PHE A 1 52  ? 120.992 151.646 104.623 1.00 146.00 ? 633 PHE A CG  1 
ATOM 7    C CD1 . PHE A 1 52  ? 121.762 152.508 103.851 1.00 146.00 ? 633 PHE A CD1 1 
ATOM 8    C CD2 . PHE A 1 52  ? 120.487 152.099 105.834 1.00 146.00 ? 633 PHE A CD2 1 
ATOM 9    C CE1 . PHE A 1 52  ? 122.029 153.798 104.284 1.00 146.00 ? 633 PHE A CE1 1 
ATOM 10   C CE2 . PHE A 1 52  ? 120.750 153.386 106.274 1.00 146.00 ? 633 PHE A CE2 1 
ATOM 11   C CZ  . PHE A 1 52  ? 121.522 154.237 105.497 1.00 146.00 ? 633 PHE A CZ  1 
ATOM 12   N N   . VAL A 1 53  ? 123.493 149.739 106.037 1.00 143.82 ? 634 VAL A N   1 
ATOM 13   C CA  . VAL A 1 53  ? 124.067 149.666 107.376 1.00 143.82 ? 634 VAL A CA  1 
ATOM 14   C C   . VAL A 1 53  ? 123.701 150.937 108.133 1.00 143.82 ? 634 VAL A C   1 
ATOM 15   O O   . VAL A 1 53  ? 123.478 151.994 107.528 1.00 143.82 ? 634 VAL A O   1 
ATOM 16   C CB  . VAL A 1 53  ? 125.590 149.447 107.328 1.00 143.82 ? 634 VAL A CB  1 
ATOM 17   C CG1 . VAL A 1 53  ? 125.904 148.123 106.652 1.00 143.82 ? 634 VAL A CG1 1 
ATOM 18   C CG2 . VAL A 1 53  ? 126.293 150.579 106.587 1.00 143.82 ? 634 VAL A CG2 1 
ATOM 19   N N   . GLY A 1 54  ? 123.595 150.825 109.457 1.00 148.41 ? 635 GLY A N   1 
ATOM 20   C CA  . GLY A 1 54  ? 123.195 151.958 110.259 1.00 148.41 ? 635 GLY A CA  1 
ATOM 21   C C   . GLY A 1 54  ? 124.360 152.644 110.942 1.00 148.41 ? 635 GLY A C   1 
ATOM 22   O O   . GLY A 1 54  ? 125.459 152.104 111.065 1.00 148.41 ? 635 GLY A O   1 
ATOM 23   N N   . THR A 1 55  ? 124.103 153.876 111.391 1.00 155.43 ? 636 THR A N   1 
ATOM 24   C CA  . THR A 1 55  ? 125.070 154.662 112.150 1.00 155.43 ? 636 THR A CA  1 
ATOM 25   C C   . THR A 1 55  ? 124.514 155.030 113.520 1.00 155.43 ? 636 THR A C   1 
ATOM 26   O O   . THR A 1 55  ? 124.846 156.083 114.069 1.00 155.43 ? 636 THR A O   1 
ATOM 27   C CB  . THR A 1 55  ? 125.485 155.926 111.393 1.00 155.43 ? 636 THR A CB  1 
ATOM 28   O OG1 . THR A 1 55  ? 124.335 156.749 111.160 1.00 155.43 ? 636 THR A OG1 1 
ATOM 29   C CG2 . THR A 1 55  ? 126.149 155.580 110.063 1.00 155.43 ? 636 THR A CG2 1 
ATOM 30   N N   . CYS A 1 56  ? 123.661 154.174 114.077 1.00 144.44 ? 637 CYS A N   1 
ATOM 31   C CA  . CYS A 1 56  ? 123.116 154.396 115.408 1.00 144.44 ? 637 CYS A CA  1 
ATOM 32   C C   . CYS A 1 56  ? 124.174 154.130 116.468 1.00 144.44 ? 637 CYS A C   1 
ATOM 33   O O   . CYS A 1 56  ? 124.828 153.084 116.466 1.00 144.44 ? 637 CYS A O   1 
ATOM 34   C CB  . CYS A 1 56  ? 121.906 153.495 115.646 1.00 144.44 ? 637 CYS A CB  1 
ATOM 35   S SG  . CYS A 1 56  ? 121.090 153.758 117.229 1.00 144.44 ? 637 CYS A SG  1 
ATOM 36   N N   . LEU A 1 57  ? 124.335 155.082 117.382 1.00 150.17 ? 638 LEU A N   1 
ATOM 37   C CA  . LEU A 1 57  ? 125.373 155.031 118.406 1.00 150.17 ? 638 LEU A CA  1 
ATOM 38   C C   . LEU A 1 57  ? 124.761 155.259 119.785 1.00 150.17 ? 638 LEU A C   1 
ATOM 39   O O   . LEU A 1 57  ? 125.231 156.074 120.581 1.00 150.17 ? 638 LEU A O   1 
ATOM 40   C CB  . LEU A 1 57  ? 126.466 156.051 118.090 1.00 150.17 ? 638 LEU A CB  1 
ATOM 41   C CG  . LEU A 1 57  ? 127.888 155.809 118.606 1.00 150.17 ? 638 LEU A CG  1 
ATOM 42   C CD1 . LEU A 1 57  ? 128.488 154.577 117.949 1.00 150.17 ? 638 LEU A CD1 1 
ATOM 43   C CD2 . LEU A 1 57  ? 128.759 157.033 118.356 1.00 150.17 ? 638 LEU A CD2 1 
ATOM 44   N N   . ASP A 1 58  ? 123.677 154.546 120.081 1.00 146.71 ? 639 ASP A N   1 
ATOM 45   C CA  . ASP A 1 58  ? 123.016 154.729 121.364 1.00 146.71 ? 639 ASP A CA  1 
ATOM 46   C C   . ASP A 1 58  ? 122.424 153.398 121.809 1.00 146.71 ? 639 ASP A C   1 
ATOM 47   O O   . ASP A 1 58  ? 121.985 152.596 120.980 1.00 146.71 ? 639 ASP A O   1 
ATOM 48   C CB  . ASP A 1 58  ? 121.938 155.824 121.275 1.00 146.71 ? 639 ASP A CB  1 
ATOM 49   C CG  . ASP A 1 58  ? 121.223 156.071 122.599 1.00 146.71 ? 639 ASP A CG  1 
ATOM 50   O OD1 . ASP A 1 58  ? 121.843 155.868 123.666 1.00 146.71 ? 639 ASP A OD1 1 
ATOM 51   O OD2 . ASP A 1 58  ? 120.050 156.497 122.574 1.00 146.71 ? 639 ASP A OD2 1 
ATOM 52   N N   . MET A 1 59  ? 122.445 153.172 123.124 1.00 135.32 ? 640 MET A N   1 
ATOM 53   C CA  . MET A 1 59  ? 121.845 152.016 123.776 1.00 135.32 ? 640 MET A CA  1 
ATOM 54   C C   . MET A 1 59  ? 120.334 152.041 123.571 1.00 135.32 ? 640 MET A C   1 
ATOM 55   O O   . MET A 1 59  ? 119.708 151.008 123.312 1.00 135.32 ? 640 MET A O   1 
ATOM 56   C CB  . MET A 1 59  ? 122.201 152.046 125.268 1.00 135.32 ? 640 MET A CB  1 
ATOM 57   C CG  . MET A 1 59  ? 121.354 151.204 126.210 1.00 135.32 ? 640 MET A CG  1 
ATOM 58   S SD  . MET A 1 59  ? 121.284 149.463 125.763 1.00 135.32 ? 640 MET A SD  1 
ATOM 59   C CE  . MET A 1 59  ? 122.310 148.789 127.060 1.00 135.32 ? 640 MET A CE  1 
ATOM 60   N N   . CYS A 1 60  ? 119.758 153.236 123.643 1.00 150.40 ? 641 CYS A N   1 
ATOM 61   C CA  . CYS A 1 60  ? 118.321 153.461 123.675 1.00 150.40 ? 641 CYS A CA  1 
ATOM 62   C C   . CYS A 1 60  ? 117.822 153.887 122.298 1.00 150.40 ? 641 CYS A C   1 
ATOM 63   O O   . CYS A 1 60  ? 118.634 154.223 121.426 1.00 150.40 ? 641 CYS A O   1 
ATOM 64   C CB  . CYS A 1 60  ? 118.006 154.535 124.719 1.00 150.40 ? 641 CYS A CB  1 
ATOM 65   S SG  . CYS A 1 60  ? 118.180 153.975 126.425 1.00 150.40 ? 641 CYS A SG  1 
ATOM 66   N N   . PRO A 1 61  ? 116.514 153.854 122.043 1.00 149.33 ? 642 PRO A N   1 
ATOM 67   C CA  . PRO A 1 61  ? 115.971 154.649 120.937 1.00 149.33 ? 642 PRO A CA  1 
ATOM 68   C C   . PRO A 1 61  ? 116.116 156.136 121.217 1.00 149.33 ? 642 PRO A C   1 
ATOM 69   O O   . PRO A 1 61  ? 116.171 156.574 122.366 1.00 149.33 ? 642 PRO A O   1 
ATOM 70   C CB  . PRO A 1 61  ? 114.499 154.229 120.883 1.00 149.33 ? 642 PRO A CB  1 
ATOM 71   C CG  . PRO A 1 61  ? 114.484 152.890 121.474 1.00 149.33 ? 642 PRO A CG  1 
ATOM 72   C CD  . PRO A 1 61  ? 115.515 152.903 122.559 1.00 149.33 ? 642 PRO A CD  1 
ATOM 73   N N   . GLU A 1 62  ? 116.197 156.916 120.142 1.00 150.42 ? 643 GLU A N   1 
ATOM 74   C CA  . GLU A 1 62  ? 116.400 158.352 120.289 1.00 150.42 ? 643 GLU A CA  1 
ATOM 75   C C   . GLU A 1 62  ? 115.081 159.112 120.215 1.00 150.42 ? 643 GLU A C   1 
ATOM 76   O O   . GLU A 1 62  ? 115.008 160.272 120.633 1.00 150.42 ? 643 GLU A O   1 
ATOM 77   C CB  . GLU A 1 62  ? 117.391 158.908 119.243 1.00 150.42 ? 643 GLU A CB  1 
ATOM 78   C CG  . GLU A 1 62  ? 118.778 158.215 119.008 1.00 150.42 ? 643 GLU A CG  1 
ATOM 79   C CD  . GLU A 1 62  ? 118.750 156.809 118.415 1.00 150.42 ? 643 GLU A CD  1 
ATOM 80   O OE1 . GLU A 1 62  ? 118.065 156.600 117.394 1.00 150.42 ? 643 GLU A OE1 1 
ATOM 81   O OE2 . GLU A 1 62  ? 119.394 155.914 119.000 1.00 150.42 ? 643 GLU A OE2 1 
ATOM 82   N N   . LYS A 1 63  ? 114.032 158.477 119.699 1.00 149.62 ? 644 LYS A N   1 
ATOM 83   C CA  . LYS A 1 63  ? 112.757 159.158 119.515 1.00 149.62 ? 644 LYS A CA  1 
ATOM 84   C C   . LYS A 1 63  ? 111.636 158.410 120.229 1.00 149.62 ? 644 LYS A C   1 
ATOM 85   O O   . LYS A 1 63  ? 110.733 159.030 120.803 1.00 149.62 ? 644 LYS A O   1 
ATOM 86   C CB  . LYS A 1 63  ? 112.459 159.305 118.018 1.00 149.62 ? 644 LYS A CB  1 
ATOM 87   C CG  . LYS A 1 63  ? 111.118 159.936 117.676 1.00 149.62 ? 644 LYS A CG  1 
ATOM 88   C CD  . LYS A 1 63  ? 111.083 160.403 116.232 1.00 149.62 ? 644 LYS A CD  1 
ATOM 89   C CE  . LYS A 1 63  ? 109.729 160.141 115.597 1.00 149.62 ? 644 LYS A CE  1 
ATOM 90   N NZ  . LYS A 1 63  ? 109.856 159.830 114.148 1.00 149.62 ? 644 LYS A NZ  1 
ATOM 91   N N   . GLU A 1 64  ? 111.713 157.075 120.229 1.00 153.49 ? 645 GLU A N   1 
ATOM 92   C CA  . GLU A 1 64  ? 110.628 156.219 120.700 1.00 153.49 ? 645 GLU A CA  1 
ATOM 93   C C   . GLU A 1 64  ? 110.428 156.275 122.213 1.00 153.49 ? 645 GLU A C   1 
ATOM 94   O O   . GLU A 1 64  ? 109.333 155.944 122.682 1.00 153.49 ? 645 GLU A O   1 
ATOM 95   C CB  . GLU A 1 64  ? 110.890 154.780 120.232 1.00 153.49 ? 645 GLU A CB  1 
ATOM 96   C CG  . GLU A 1 64  ? 109.671 153.854 120.162 1.00 153.49 ? 645 GLU A CG  1 
ATOM 97   C CD  . GLU A 1 64  ? 109.450 153.069 121.440 1.00 153.49 ? 645 GLU A CD  1 
ATOM 98   O OE1 . GLU A 1 64  ? 110.438 152.824 122.164 1.00 153.49 ? 645 GLU A OE1 1 
ATOM 99   O OE2 . GLU A 1 64  ? 108.292 152.696 121.721 1.00 153.49 ? 645 GLU A OE2 1 
ATOM 100  N N   . ARG A 1 65  ? 111.434 156.711 122.983 1.00 150.81 ? 646 ARG A N   1 
ATOM 101  C CA  . ARG A 1 65  ? 111.240 156.872 124.424 1.00 150.81 ? 646 ARG A CA  1 
ATOM 102  C C   . ARG A 1 65  ? 110.308 158.037 124.732 1.00 150.81 ? 646 ARG A C   1 
ATOM 103  O O   . ARG A 1 65  ? 109.544 157.988 125.702 1.00 150.81 ? 646 ARG A O   1 
ATOM 104  C CB  . ARG A 1 65  ? 112.579 157.071 125.136 1.00 150.81 ? 646 ARG A CB  1 
ATOM 105  C CG  . ARG A 1 65  ? 113.570 157.947 124.401 1.00 150.81 ? 646 ARG A CG  1 
ATOM 106  C CD  . ARG A 1 65  ? 114.925 157.908 125.085 1.00 150.81 ? 646 ARG A CD  1 
ATOM 107  N NE  . ARG A 1 65  ? 115.972 158.440 124.221 1.00 150.81 ? 646 ARG A NE  1 
ATOM 108  C CZ  . ARG A 1 65  ? 117.173 158.815 124.639 1.00 150.81 ? 646 ARG A CZ  1 
ATOM 109  N NH1 . ARG A 1 65  ? 117.521 158.729 125.912 1.00 150.81 ? 646 ARG A NH1 1 
ATOM 110  N NH2 . ARG A 1 65  ? 118.049 159.285 123.755 1.00 150.81 ? 646 ARG A NH2 1 
ATOM 111  N N   . TYR A 1 66  ? 110.349 159.089 123.909 1.00 148.40 ? 647 TYR A N   1 
ATOM 112  C CA  . TYR A 1 66  ? 109.440 160.218 124.089 1.00 148.40 ? 647 TYR A CA  1 
ATOM 113  C C   . TYR A 1 66  ? 108.003 159.831 123.757 1.00 148.40 ? 647 TYR A C   1 
ATOM 114  O O   . TYR A 1 66  ? 107.065 160.244 124.452 1.00 148.40 ? 647 TYR A O   1 
ATOM 115  C CB  . TYR A 1 66  ? 109.897 161.393 123.226 1.00 148.40 ? 647 TYR A CB  1 
ATOM 116  C CG  . TYR A 1 66  ? 111.180 162.035 123.705 1.00 148.40 ? 647 TYR A CG  1 
ATOM 117  C CD1 . TYR A 1 66  ? 111.439 162.187 125.065 1.00 148.40 ? 647 TYR A CD1 1 
ATOM 118  C CD2 . TYR A 1 66  ? 112.137 162.481 122.797 1.00 148.40 ? 647 TYR A CD2 1 
ATOM 119  C CE1 . TYR A 1 66  ? 112.615 162.772 125.509 1.00 148.40 ? 647 TYR A CE1 1 
ATOM 120  C CE2 . TYR A 1 66  ? 113.316 163.068 123.231 1.00 148.40 ? 647 TYR A CE2 1 
ATOM 121  C CZ  . TYR A 1 66  ? 113.547 163.210 124.587 1.00 148.40 ? 647 TYR A CZ  1 
ATOM 122  O OH  . TYR A 1 66  ? 114.716 163.791 125.021 1.00 148.40 ? 647 TYR A OH  1 
ATOM 123  N N   . MET A 1 67  ? 107.815 159.025 122.706 1.00 152.63 ? 648 MET A N   1 
ATOM 124  C CA  . MET A 1 67  ? 106.491 158.504 122.377 1.00 152.63 ? 648 MET A CA  1 
ATOM 125  C C   . MET A 1 67  ? 105.991 157.532 123.439 1.00 152.63 ? 648 MET A C   1 
ATOM 126  O O   . MET A 1 67  ? 104.786 157.482 123.718 1.00 152.63 ? 648 MET A O   1 
ATOM 127  C CB  . MET A 1 67  ? 106.520 157.824 121.008 1.00 152.63 ? 648 MET A CB  1 
ATOM 128  C CG  . MET A 1 67  ? 106.722 158.779 119.845 1.00 152.63 ? 648 MET A CG  1 
ATOM 129  S SD  . MET A 1 67  ? 105.246 159.738 119.462 1.00 152.63 ? 648 MET A SD  1 
ATOM 130  C CE  . MET A 1 67  ? 105.332 159.789 117.674 1.00 152.63 ? 648 MET A CE  1 
ATOM 131  N N   . ARG A 1 68  ? 106.907 156.761 124.035 1.00 147.43 ? 649 ARG A N   1 
ATOM 132  C CA  . ARG A 1 68  ? 106.571 155.891 125.159 1.00 147.43 ? 649 ARG A CA  1 
ATOM 133  C C   . ARG A 1 68  ? 106.141 156.701 126.375 1.00 147.43 ? 649 ARG A C   1 
ATOM 134  O O   . ARG A 1 68  ? 105.199 156.329 127.083 1.00 147.43 ? 649 ARG A O   1 
ATOM 135  C CB  . ARG A 1 68  ? 107.776 155.016 125.502 1.00 147.43 ? 649 ARG A CB  1 
ATOM 136  C CG  . ARG A 1 68  ? 107.464 153.840 126.399 1.00 147.43 ? 649 ARG A CG  1 
ATOM 137  C CD  . ARG A 1 68  ? 107.385 152.567 125.589 1.00 147.43 ? 649 ARG A CD  1 
ATOM 138  N NE  . ARG A 1 68  ? 108.559 152.386 124.743 1.00 147.43 ? 649 ARG A NE  1 
ATOM 139  C CZ  . ARG A 1 68  ? 109.661 151.750 125.117 1.00 147.43 ? 649 ARG A CZ  1 
ATOM 140  N NH1 . ARG A 1 68  ? 109.775 151.213 126.320 1.00 147.43 ? 649 ARG A NH1 1 
ATOM 141  N NH2 . ARG A 1 68  ? 110.675 151.651 124.262 1.00 147.43 ? 649 ARG A NH2 1 
ATOM 142  N N   . GLU A 1 69  ? 106.831 157.817 126.629 1.00 158.18 ? 650 GLU A N   1 
ATOM 143  C CA  . GLU A 1 69  ? 106.521 158.659 127.779 1.00 158.18 ? 650 GLU A CA  1 
ATOM 144  C C   . GLU A 1 69  ? 105.198 159.393 127.596 1.00 158.18 ? 650 GLU A C   1 
ATOM 145  O O   . GLU A 1 69  ? 104.453 159.593 128.563 1.00 158.18 ? 650 GLU A O   1 
ATOM 146  C CB  . GLU A 1 69  ? 107.666 159.648 128.009 1.00 158.18 ? 650 GLU A CB  1 
ATOM 147  C CG  . GLU A 1 69  ? 107.658 160.340 129.359 1.00 158.18 ? 650 GLU A CG  1 
ATOM 148  C CD  . GLU A 1 69  ? 106.980 161.695 129.317 1.00 158.18 ? 650 GLU A CD  1 
ATOM 149  O OE1 . GLU A 1 69  ? 107.007 162.338 128.247 1.00 158.18 ? 650 GLU A OE1 1 
ATOM 150  O OE2 . GLU A 1 69  ? 106.428 162.118 130.354 1.00 158.18 ? 650 GLU A OE2 1 
ATOM 151  N N   . THR A 1 70  ? 104.888 159.807 126.365 1.00 158.71 ? 651 THR A N   1 
ATOM 152  C CA  . THR A 1 70  ? 103.613 160.476 126.120 1.00 158.71 ? 651 THR A CA  1 
ATOM 153  C C   . THR A 1 70  ? 102.453 159.485 126.126 1.00 158.71 ? 651 THR A C   1 
ATOM 154  O O   . THR A 1 70  ? 101.381 159.778 126.669 1.00 158.71 ? 651 THR A O   1 
ATOM 155  C CB  . THR A 1 70  ? 103.653 161.248 124.800 1.00 158.71 ? 651 THR A CB  1 
ATOM 156  O OG1 . THR A 1 70  ? 104.085 160.382 123.745 1.00 158.71 ? 651 THR A OG1 1 
ATOM 157  C CG2 . THR A 1 70  ? 104.591 162.444 124.903 1.00 158.71 ? 651 THR A CG2 1 
ATOM 158  N N   . ARG A 1 71  ? 102.645 158.305 125.535 1.00 152.66 ? 652 ARG A N   1 
ATOM 159  C CA  . ARG A 1 71  ? 101.550 157.353 125.395 1.00 152.66 ? 652 ARG A CA  1 
ATOM 160  C C   . ARG A 1 71  ? 101.460 156.349 126.539 1.00 152.66 ? 652 ARG A C   1 
ATOM 161  O O   . ARG A 1 71  ? 100.550 155.511 126.517 1.00 152.66 ? 652 ARG A O   1 
ATOM 162  C CB  . ARG A 1 71  ? 101.668 156.609 124.059 1.00 152.66 ? 652 ARG A CB  1 
ATOM 163  C CG  . ARG A 1 71  ? 101.239 157.385 122.787 1.00 152.66 ? 652 ARG A CG  1 
ATOM 164  C CD  . ARG A 1 71  ? 99.840  158.041 122.834 1.00 152.66 ? 652 ARG A CD  1 
ATOM 165  N NE  . ARG A 1 71  ? 99.814  159.389 123.397 1.00 152.66 ? 652 ARG A NE  1 
ATOM 166  C CZ  . ARG A 1 71  ? 99.951  160.503 122.691 1.00 152.66 ? 652 ARG A CZ  1 
ATOM 167  N NH1 . ARG A 1 71  ? 100.119 160.474 121.380 1.00 152.66 ? 652 ARG A NH1 1 
ATOM 168  N NH2 . ARG A 1 71  ? 99.917  161.676 123.317 1.00 152.66 ? 652 ARG A NH2 1 
ATOM 169  N N   . SER A 1 72  ? 102.390 156.418 127.506 1.00 147.98 ? 653 SER A N   1 
ATOM 170  C CA  . SER A 1 72  ? 102.355 155.681 128.782 1.00 147.98 ? 653 SER A CA  1 
ATOM 171  C C   . SER A 1 72  ? 102.356 154.162 128.588 1.00 147.98 ? 653 SER A C   1 
ATOM 172  O O   . SER A 1 72  ? 101.468 153.450 129.063 1.00 147.98 ? 653 SER A O   1 
ATOM 173  C CB  . SER A 1 72  ? 101.171 156.123 129.650 1.00 147.98 ? 653 SER A CB  1 
ATOM 174  O OG  . SER A 1 72  ? 100.872 155.151 130.636 1.00 147.98 ? 653 SER A OG  1 
ATOM 175  N N   . GLN A 1 73  ? 103.368 153.666 127.877 1.00 139.97 ? 654 GLN A N   1 
ATOM 176  C CA  . GLN A 1 73  ? 103.570 152.235 127.687 1.00 139.97 ? 654 GLN A CA  1 
ATOM 177  C C   . GLN A 1 73  ? 104.879 151.754 128.304 1.00 139.97 ? 654 GLN A C   1 
ATOM 178  O O   . GLN A 1 73  ? 105.535 150.866 127.750 1.00 139.97 ? 654 GLN A O   1 
ATOM 179  C CB  . GLN A 1 73  ? 103.523 151.885 126.200 1.00 139.97 ? 654 GLN A CB  1 
ATOM 180  C CG  . GLN A 1 73  ? 102.119 151.795 125.625 1.00 139.97 ? 654 GLN A CG  1 
ATOM 181  C CD  . GLN A 1 73  ? 102.108 151.799 124.109 1.00 139.97 ? 654 GLN A CD  1 
ATOM 182  O OE1 . GLN A 1 73  ? 103.139 152.002 123.469 1.00 139.97 ? 654 GLN A OE1 1 
ATOM 183  N NE2 . GLN A 1 73  ? 100.937 151.572 123.525 1.00 139.97 ? 654 GLN A NE2 1 
ATOM 184  N N   . LEU A 1 74  ? 105.258 152.318 129.449 1.00 140.60 ? 655 LEU A N   1 
ATOM 185  C CA  . LEU A 1 74  ? 106.570 152.107 130.043 1.00 140.60 ? 655 LEU A CA  1 
ATOM 186  C C   . LEU A 1 74  ? 106.704 150.708 130.640 1.00 140.60 ? 655 LEU A C   1 
ATOM 187  O O   . LEU A 1 74  ? 105.720 150.040 130.969 1.00 140.60 ? 655 LEU A O   1 
ATOM 188  C CB  . LEU A 1 74  ? 106.853 153.139 131.140 1.00 140.60 ? 655 LEU A CB  1 
ATOM 189  C CG  . LEU A 1 74  ? 107.417 154.530 130.820 1.00 140.60 ? 655 LEU A CG  1 
ATOM 190  C CD1 . LEU A 1 74  ? 108.764 154.404 130.119 1.00 140.60 ? 655 LEU A CD1 1 
ATOM 191  C CD2 . LEU A 1 74  ? 106.463 155.426 130.039 1.00 140.60 ? 655 LEU A CD2 1 
ATOM 192  N N   . SER A 1 75  ? 107.955 150.275 130.774 1.00 133.74 ? 656 SER A N   1 
ATOM 193  C CA  . SER A 1 75  ? 108.312 149.078 131.525 1.00 133.74 ? 656 SER A CA  1 
ATOM 194  C C   . SER A 1 75  ? 108.784 149.540 132.898 1.00 133.74 ? 656 SER A C   1 
ATOM 195  O O   . SER A 1 75  ? 109.601 150.459 132.999 1.00 133.74 ? 656 SER A O   1 
ATOM 196  C CB  . SER A 1 75  ? 109.395 148.280 130.805 1.00 133.74 ? 656 SER A CB  1 
ATOM 197  O OG  . SER A 1 75  ? 110.568 149.058 130.642 1.00 133.74 ? 656 SER A OG  1 
ATOM 198  N N   . VAL A 1 76  ? 108.276 148.896 133.953 1.00 131.88 ? 657 VAL A N   1 
ATOM 199  C CA  . VAL A 1 76  ? 108.486 149.402 135.308 1.00 131.88 ? 657 VAL A CA  1 
ATOM 200  C C   . VAL A 1 76  ? 109.890 149.059 135.804 1.00 131.88 ? 657 VAL A C   1 
ATOM 201  O O   . VAL A 1 76  ? 110.383 149.659 136.770 1.00 131.88 ? 657 VAL A O   1 
ATOM 202  C CB  . VAL A 1 76  ? 107.374 148.856 136.239 1.00 131.88 ? 657 VAL A CB  1 
ATOM 203  C CG1 . VAL A 1 76  ? 107.544 147.365 136.498 1.00 131.88 ? 657 VAL A CG1 1 
ATOM 204  C CG2 . VAL A 1 76  ? 107.225 149.669 137.539 1.00 131.88 ? 657 VAL A CG2 1 
ATOM 205  N N   . PHE A 1 77  ? 110.572 148.120 135.140 1.00 128.65 ? 658 PHE A N   1 
ATOM 206  C CA  . PHE A 1 77  ? 111.921 147.761 135.566 1.00 128.65 ? 658 PHE A CA  1 
ATOM 207  C C   . PHE A 1 77  ? 112.927 148.843 135.193 1.00 128.65 ? 658 PHE A C   1 
ATOM 208  O O   . PHE A 1 77  ? 113.849 149.130 135.966 1.00 128.65 ? 658 PHE A O   1 
ATOM 209  C CB  . PHE A 1 77  ? 112.335 146.419 134.963 1.00 128.65 ? 658 PHE A CB  1 
ATOM 210  C CG  . PHE A 1 77  ? 113.701 145.963 135.396 1.00 128.65 ? 658 PHE A CG  1 
ATOM 211  C CD1 . PHE A 1 77  ? 113.895 145.440 136.668 1.00 128.65 ? 658 PHE A CD1 1 
ATOM 212  C CD2 . PHE A 1 77  ? 114.793 146.069 134.541 1.00 128.65 ? 658 PHE A CD2 1 
ATOM 213  C CE1 . PHE A 1 77  ? 115.153 145.025 137.080 1.00 128.65 ? 658 PHE A CE1 1 
ATOM 214  C CE2 . PHE A 1 77  ? 116.053 145.663 134.948 1.00 128.65 ? 658 PHE A CE2 1 
ATOM 215  C CZ  . PHE A 1 77  ? 116.233 145.136 136.216 1.00 128.65 ? 658 PHE A CZ  1 
ATOM 216  N N   . GLU A 1 78  ? 112.769 149.463 134.024 1.00 134.43 ? 659 GLU A N   1 
ATOM 217  C CA  . GLU A 1 78  ? 113.731 150.455 133.544 1.00 134.43 ? 659 GLU A CA  1 
ATOM 218  C C   . GLU A 1 78  ? 113.022 151.798 133.402 1.00 134.43 ? 659 GLU A C   1 
ATOM 219  O O   . GLU A 1 78  ? 112.645 152.199 132.298 1.00 134.43 ? 659 GLU A O   1 
ATOM 220  C CB  . GLU A 1 78  ? 114.351 150.005 132.227 1.00 134.43 ? 659 GLU A CB  1 
ATOM 221  C CG  . GLU A 1 78  ? 115.589 149.142 132.389 1.00 134.43 ? 659 GLU A CG  1 
ATOM 222  C CD  . GLU A 1 78  ? 116.393 149.041 131.111 1.00 134.43 ? 659 GLU A CD  1 
ATOM 223  O OE1 . GLU A 1 78  ? 115.948 149.596 130.086 1.00 134.43 ? 659 GLU A OE1 1 
ATOM 224  O OE2 . GLU A 1 78  ? 117.468 148.406 131.130 1.00 134.43 ? 659 GLU A OE2 1 
ATOM 225  N N   . VAL A 1 79  ? 112.875 152.494 134.532 1.00 144.92 ? 660 VAL A N   1 
ATOM 226  C CA  . VAL A 1 79  ? 112.464 153.894 134.588 1.00 144.92 ? 660 VAL A CA  1 
ATOM 227  C C   . VAL A 1 79  ? 113.292 154.545 135.684 1.00 144.92 ? 660 VAL A C   1 
ATOM 228  O O   . VAL A 1 79  ? 114.023 153.875 136.417 1.00 144.92 ? 660 VAL A O   1 
ATOM 229  C CB  . VAL A 1 79  ? 110.956 154.110 134.890 1.00 144.92 ? 660 VAL A CB  1 
ATOM 230  C CG1 . VAL A 1 79  ? 110.063 153.698 133.725 1.00 144.92 ? 660 VAL A CG1 1 
ATOM 231  C CG2 . VAL A 1 79  ? 110.559 153.365 136.155 1.00 144.92 ? 660 VAL A CG2 1 
ATOM 232  N N   . VAL A 1 80  ? 113.179 155.863 135.796 1.00 156.55 ? 661 VAL A N   1 
ATOM 233  C CA  . VAL A 1 80  ? 113.741 156.511 136.985 1.00 156.55 ? 661 VAL A CA  1 
ATOM 234  C C   . VAL A 1 80  ? 112.811 156.254 138.167 1.00 156.55 ? 661 VAL A C   1 
ATOM 235  O O   . VAL A 1 80  ? 111.596 156.056 137.964 1.00 156.55 ? 661 VAL A O   1 
ATOM 236  C CB  . VAL A 1 80  ? 113.937 158.020 136.747 1.00 156.55 ? 661 VAL A CB  1 
ATOM 237  C CG1 . VAL A 1 80  ? 115.124 158.258 135.825 1.00 156.55 ? 661 VAL A CG1 1 
ATOM 238  C CG2 . VAL A 1 80  ? 112.679 158.647 136.171 1.00 156.55 ? 661 VAL A CG2 1 
ATOM 239  N N   . PRO A 1 81  ? 113.317 156.182 139.400 1.00 162.67 ? 662 PRO A N   1 
ATOM 240  C CA  . PRO A 1 81  ? 112.420 156.047 140.557 1.00 162.67 ? 662 PRO A CA  1 
ATOM 241  C C   . PRO A 1 81  ? 111.635 157.331 140.790 1.00 162.67 ? 662 PRO A C   1 
ATOM 242  O O   . PRO A 1 81  ? 112.210 158.394 141.033 1.00 162.67 ? 662 PRO A O   1 
ATOM 243  C CB  . PRO A 1 81  ? 113.377 155.753 141.718 1.00 162.67 ? 662 PRO A CB  1 
ATOM 244  C CG  . PRO A 1 81  ? 114.584 155.166 141.069 1.00 162.67 ? 662 PRO A CG  1 
ATOM 245  C CD  . PRO A 1 81  ? 114.716 155.884 139.755 1.00 162.67 ? 662 PRO A CD  1 
ATOM 246  N N   . GLY A 1 82  ? 110.311 157.220 140.711 1.00 168.48 ? 663 GLY A N   1 
ATOM 247  C CA  . GLY A 1 82  ? 109.433 158.365 140.817 1.00 168.48 ? 663 GLY A CA  1 
ATOM 248  C C   . GLY A 1 82  ? 108.578 158.633 139.599 1.00 168.48 ? 663 GLY A C   1 
ATOM 249  O O   . GLY A 1 82  ? 108.064 159.753 139.469 1.00 168.48 ? 663 GLY A O   1 
ATOM 250  N N   . THR A 1 83  ? 108.411 157.642 138.719 1.00 173.44 ? 664 THR A N   1 
ATOM 251  C CA  . THR A 1 83  ? 107.638 157.530 137.458 1.00 173.44 ? 664 THR A CA  1 
ATOM 252  C C   . THR A 1 83  ? 107.846 158.776 136.576 1.00 173.44 ? 664 THR A C   1 
ATOM 253  O O   . THR A 1 83  ? 108.939 159.362 136.586 1.00 173.44 ? 664 THR A O   1 
ATOM 254  C CB  . THR A 1 83  ? 106.146 157.137 137.733 1.00 173.44 ? 664 THR A CB  1 
ATOM 255  O OG1 . THR A 1 83  ? 105.483 156.876 136.489 1.00 173.44 ? 664 THR A OG1 1 
ATOM 256  C CG2 . THR A 1 83  ? 105.309 158.160 138.560 1.00 173.44 ? 664 THR A CG2 1 
ATOM 257  N N   . ASP A 1 84  ? 106.833 159.120 135.765 1.00 173.96 ? 665 ASP A N   1 
ATOM 258  C CA  . ASP A 1 84  ? 106.747 160.306 134.910 1.00 173.96 ? 665 ASP A CA  1 
ATOM 259  C C   . ASP A 1 84  ? 107.841 160.340 133.848 1.00 173.96 ? 665 ASP A C   1 
ATOM 260  O O   . ASP A 1 84  ? 107.581 160.033 132.680 1.00 173.96 ? 665 ASP A O   1 
ATOM 261  C CB  . ASP A 1 84  ? 106.768 161.599 135.738 1.00 173.96 ? 665 ASP A CB  1 
ATOM 262  C CG  . ASP A 1 84  ? 106.468 162.829 134.904 1.00 173.96 ? 665 ASP A CG  1 
ATOM 263  O OD1 . ASP A 1 84  ? 105.286 163.040 134.559 1.00 173.96 ? 665 ASP A OD1 1 
ATOM 264  O OD2 . ASP A 1 84  ? 107.412 163.582 134.590 1.00 173.96 ? 665 ASP A OD2 1 
ATOM 265  N N   . GLN A 1 85  ? 109.054 160.729 134.243 1.00 168.79 ? 666 GLN A N   1 
ATOM 266  C CA  . GLN A 1 85  ? 110.159 160.850 133.299 1.00 168.79 ? 666 GLN A CA  1 
ATOM 267  C C   . GLN A 1 85  ? 110.632 159.479 132.832 1.00 168.79 ? 666 GLN A C   1 
ATOM 268  O O   . GLN A 1 85  ? 110.575 158.499 133.579 1.00 168.79 ? 666 GLN A O   1 
ATOM 269  C CB  . GLN A 1 85  ? 111.328 161.611 133.931 1.00 168.79 ? 666 GLN A CB  1 
ATOM 270  C CG  . GLN A 1 85  ? 111.067 163.080 134.240 1.00 168.79 ? 666 GLN A CG  1 
ATOM 271  C CD  . GLN A 1 85  ? 110.429 163.296 135.598 1.00 168.79 ? 666 GLN A CD  1 
ATOM 272  O OE1 . GLN A 1 85  ? 110.457 162.415 136.457 1.00 168.79 ? 666 GLN A OE1 1 
ATOM 273  N NE2 . GLN A 1 85  ? 109.851 164.474 135.800 1.00 168.79 ? 666 GLN A NE2 1 
ATOM 274  N N   . VAL A 1 86  ? 111.080 159.411 131.579 1.00 155.91 ? 667 VAL A N   1 
ATOM 275  C CA  . VAL A 1 86  ? 111.718 158.201 131.081 1.00 155.91 ? 667 VAL A CA  1 
ATOM 276  C C   . VAL A 1 86  ? 113.197 158.245 131.454 1.00 155.91 ? 667 VAL A C   1 
ATOM 277  O O   . VAL A 1 86  ? 113.780 159.324 131.632 1.00 155.91 ? 667 VAL A O   1 
ATOM 278  C CB  . VAL A 1 86  ? 111.474 158.054 129.565 1.00 155.91 ? 667 VAL A CB  1 
ATOM 279  C CG1 . VAL A 1 86  ? 112.307 159.035 128.734 1.00 155.91 ? 667 VAL A CG1 1 
ATOM 280  C CG2 . VAL A 1 86  ? 111.670 156.610 129.092 1.00 155.91 ? 667 VAL A CG2 1 
ATOM 281  N N   . ASP A 1 87  ? 113.793 157.074 131.659 1.00 149.97 ? 668 ASP A N   1 
ATOM 282  C CA  . ASP A 1 87  ? 115.204 156.984 132.026 1.00 149.97 ? 668 ASP A CA  1 
ATOM 283  C C   . ASP A 1 87  ? 116.031 157.046 130.751 1.00 149.97 ? 668 ASP A C   1 
ATOM 284  O O   . ASP A 1 87  ? 116.020 156.116 129.944 1.00 149.97 ? 668 ASP A O   1 
ATOM 285  C CB  . ASP A 1 87  ? 115.476 155.703 132.807 1.00 149.97 ? 668 ASP A CB  1 
ATOM 286  C CG  . ASP A 1 87  ? 116.773 155.763 133.592 1.00 149.97 ? 668 ASP A CG  1 
ATOM 287  O OD1 . ASP A 1 87  ? 117.421 156.830 133.599 1.00 149.97 ? 668 ASP A OD1 1 
ATOM 288  O OD2 . ASP A 1 87  ? 117.144 154.740 134.204 1.00 149.97 ? 668 ASP A OD2 1 
ATOM 289  N N   . HIS A 1 88  ? 116.766 158.148 130.569 1.00 150.37 ? 669 HIS A N   1 
ATOM 290  C CA  . HIS A 1 88  ? 117.570 158.311 129.361 1.00 150.37 ? 669 HIS A CA  1 
ATOM 291  C C   . HIS A 1 88  ? 118.811 157.429 129.378 1.00 150.37 ? 669 HIS A C   1 
ATOM 292  O O   . HIS A 1 88  ? 119.409 157.182 128.324 1.00 150.37 ? 669 HIS A O   1 
ATOM 293  C CB  . HIS A 1 88  ? 117.962 159.777 129.183 1.00 150.37 ? 669 HIS A CB  1 
ATOM 294  C CG  . HIS A 1 88  ? 116.903 160.606 128.528 1.00 150.37 ? 669 HIS A CG  1 
ATOM 295  N ND1 . HIS A 1 88  ? 117.101 161.923 128.172 1.00 150.37 ? 669 HIS A ND1 1 
ATOM 296  C CD2 . HIS A 1 88  ? 115.636 160.304 128.159 1.00 150.37 ? 669 HIS A CD2 1 
ATOM 297  C CE1 . HIS A 1 88  ? 116.002 162.396 127.614 1.00 150.37 ? 669 HIS A CE1 1 
ATOM 298  N NE2 . HIS A 1 88  ? 115.097 161.434 127.594 1.00 150.37 ? 669 HIS A NE2 1 
ATOM 299  N N   . ALA A 1 89  ? 119.219 156.952 130.556 1.00 143.43 ? 670 ALA A N   1 
ATOM 300  C CA  . ALA A 1 89  ? 120.320 156.000 130.621 1.00 143.43 ? 670 ALA A CA  1 
ATOM 301  C C   . ALA A 1 89  ? 119.908 154.623 130.116 1.00 143.43 ? 670 ALA A C   1 
ATOM 302  O O   . ALA A 1 89  ? 120.699 153.953 129.442 1.00 143.43 ? 670 ALA A O   1 
ATOM 303  C CB  . ALA A 1 89  ? 120.850 155.905 132.052 1.00 143.43 ? 670 ALA A CB  1 
ATOM 304  N N   . ALA A 1 90  ? 118.684 154.183 130.418 1.00 139.01 ? 671 ALA A N   1 
ATOM 305  C CA  . ALA A 1 90  ? 118.263 152.832 130.033 1.00 139.01 ? 671 ALA A CA  1 
ATOM 306  C C   . ALA A 1 90  ? 116.753 152.839 129.759 1.00 139.01 ? 671 ALA A C   1 
ATOM 307  O O   . ALA A 1 90  ? 115.947 152.694 130.678 1.00 139.01 ? 671 ALA A O   1 
ATOM 308  C CB  . ALA A 1 90  ? 118.629 151.820 131.099 1.00 139.01 ? 671 ALA A CB  1 
ATOM 309  N N   . ALA A 1 91  ? 116.397 153.002 128.487 1.00 136.95 ? 672 ALA A N   1 
ATOM 310  C CA  . ALA A 1 91  ? 115.027 152.865 127.992 1.00 136.95 ? 672 ALA A CA  1 
ATOM 311  C C   . ALA A 1 91  ? 115.053 152.079 126.687 1.00 136.95 ? 672 ALA A C   1 
ATOM 312  O O   . ALA A 1 91  ? 114.477 152.484 125.678 1.00 136.95 ? 672 ALA A O   1 
ATOM 313  C CB  . ALA A 1 91  ? 114.354 154.221 127.798 1.00 136.95 ? 672 ALA A CB  1 
ATOM 314  N N   . VAL A 1 92  ? 115.755 150.943 126.722 1.00 131.31 ? 673 VAL A N   1 
ATOM 315  C CA  . VAL A 1 92  ? 116.168 150.100 125.598 1.00 131.31 ? 673 VAL A CA  1 
ATOM 316  C C   . VAL A 1 92  ? 114.978 149.613 124.754 1.00 131.31 ? 673 VAL A C   1 
ATOM 317  O O   . VAL A 1 92  ? 113.850 149.519 125.253 1.00 131.31 ? 673 VAL A O   1 
ATOM 318  C CB  . VAL A 1 92  ? 117.041 148.958 126.179 1.00 131.31 ? 673 VAL A CB  1 
ATOM 319  C CG1 . VAL A 1 92  ? 116.237 148.061 127.091 1.00 131.31 ? 673 VAL A CG1 1 
ATOM 320  C CG2 . VAL A 1 92  ? 117.851 148.169 125.129 1.00 131.31 ? 673 VAL A CG2 1 
ATOM 321  N N   . LYS A 1 93  ? 115.245 149.331 123.470 1.00 131.42 ? 674 LYS A N   1 
ATOM 322  C CA  . LYS A 1 93  ? 114.305 149.289 122.346 1.00 131.42 ? 674 LYS A CA  1 
ATOM 323  C C   . LYS A 1 93  ? 113.135 148.324 122.538 1.00 131.42 ? 674 LYS A C   1 
ATOM 324  O O   . LYS A 1 93  ? 113.301 147.184 122.966 1.00 131.42 ? 674 LYS A O   1 
ATOM 325  C CB  . LYS A 1 93  ? 115.105 148.944 121.071 1.00 131.42 ? 674 LYS A CB  1 
ATOM 326  C CG  . LYS A 1 93  ? 114.419 148.988 119.681 1.00 131.42 ? 674 LYS A CG  1 
ATOM 327  C CD  . LYS A 1 93  ? 113.820 147.642 119.234 1.00 131.42 ? 674 LYS A CD  1 
ATOM 328  C CE  . LYS A 1 93  ? 113.223 147.706 117.837 1.00 131.42 ? 674 LYS A CE  1 
ATOM 329  N NZ  . LYS A 1 93  ? 112.617 146.398 117.449 1.00 131.42 ? 674 LYS A NZ  1 
ATOM 330  N N   . GLU A 1 94  ? 111.943 148.796 122.171 1.00 141.95 ? 675 GLU A N   1 
ATOM 331  C CA  . GLU A 1 94  ? 110.725 148.000 122.145 1.00 141.95 ? 675 GLU A CA  1 
ATOM 332  C C   . GLU A 1 94  ? 110.440 147.510 120.725 1.00 141.95 ? 675 GLU A C   1 
ATOM 333  O O   . GLU A 1 94  ? 110.577 148.249 119.750 1.00 141.95 ? 675 GLU A O   1 
ATOM 334  C CB  . GLU A 1 94  ? 109.538 148.823 122.652 1.00 141.95 ? 675 GLU A CB  1 
ATOM 335  C CG  . GLU A 1 94  ? 108.236 148.041 122.821 1.00 141.95 ? 675 GLU A CG  1 
ATOM 336  C CD  . GLU A 1 94  ? 107.075 148.919 123.238 1.00 141.95 ? 675 GLU A CD  1 
ATOM 337  O OE1 . GLU A 1 94  ? 107.268 150.146 123.337 1.00 141.95 ? 675 GLU A OE1 1 
ATOM 338  O OE2 . GLU A 1 94  ? 105.964 148.386 123.446 1.00 141.95 ? 675 GLU A OE2 1 
ATOM 339  N N   . TYR A 1 95  ? 110.003 146.258 120.602 1.00 129.89 ? 676 TYR A N   1 
ATOM 340  C CA  . TYR A 1 95  ? 109.473 145.752 119.343 1.00 129.89 ? 676 TYR A CA  1 
ATOM 341  C C   . TYR A 1 95  ? 107.956 145.836 119.401 1.00 129.89 ? 676 TYR A C   1 
ATOM 342  O O   . TYR A 1 95  ? 107.345 145.357 120.360 1.00 129.89 ? 676 TYR A O   1 
ATOM 343  C CB  . TYR A 1 95  ? 109.916 144.306 119.083 1.00 129.89 ? 676 TYR A CB  1 
ATOM 344  C CG  . TYR A 1 95  ? 109.049 143.553 118.094 1.00 129.89 ? 676 TYR A CG  1 
ATOM 345  C CD1 . TYR A 1 95  ? 109.018 143.908 116.744 1.00 129.89 ? 676 TYR A CD1 1 
ATOM 346  C CD2 . TYR A 1 95  ? 108.246 142.497 118.515 1.00 129.89 ? 676 TYR A CD2 1 
ATOM 347  C CE1 . TYR A 1 95  ? 108.219 143.216 115.840 1.00 129.89 ? 676 TYR A CE1 1 
ATOM 348  C CE2 . TYR A 1 95  ? 107.445 141.803 117.621 1.00 129.89 ? 676 TYR A CE2 1 
ATOM 349  C CZ  . TYR A 1 95  ? 107.436 142.165 116.289 1.00 129.89 ? 676 TYR A CZ  1 
ATOM 350  O OH  . TYR A 1 95  ? 106.639 141.473 115.405 1.00 129.89 ? 676 TYR A OH  1 
ATOM 351  N N   . SER A 1 96  ? 107.354 146.441 118.381 1.00 121.92 ? 677 SER A N   1 
ATOM 352  C CA  . SER A 1 96  ? 105.903 146.597 118.345 1.00 121.92 ? 677 SER A CA  1 
ATOM 353  C C   . SER A 1 96  ? 105.261 145.619 117.367 1.00 121.92 ? 677 SER A C   1 
ATOM 354  O O   . SER A 1 96  ? 105.547 145.646 116.171 1.00 121.92 ? 677 SER A O   1 
ATOM 355  C CB  . SER A 1 96  ? 105.524 148.032 117.973 1.00 121.92 ? 677 SER A CB  1 
ATOM 356  O OG  . SER A 1 96  ? 104.198 148.092 117.475 1.00 121.92 ? 677 SER A OG  1 
ATOM 357  N N   . GLU A 1 103 ? 110.090 147.613 104.433 1.00 147.23 ? 684 GLU A N   1 
ATOM 358  C CA  . GLU A 1 103 ? 111.492 147.728 104.821 1.00 147.23 ? 684 GLU A CA  1 
ATOM 359  C C   . GLU A 1 103 ? 111.632 148.528 106.113 1.00 147.23 ? 684 GLU A C   1 
ATOM 360  O O   . GLU A 1 103 ? 110.690 149.195 106.535 1.00 147.23 ? 684 GLU A O   1 
ATOM 361  C CB  . GLU A 1 103 ? 112.312 148.376 103.696 1.00 147.23 ? 684 GLU A CB  1 
ATOM 362  C CG  . GLU A 1 103 ? 112.335 149.907 103.692 1.00 147.23 ? 684 GLU A CG  1 
ATOM 363  C CD  . GLU A 1 103 ? 110.987 150.538 103.382 1.00 147.23 ? 684 GLU A CD  1 
ATOM 364  O OE1 . GLU A 1 103 ? 110.181 149.919 102.654 1.00 147.23 ? 684 GLU A OE1 1 
ATOM 365  O OE2 . GLU A 1 103 ? 110.735 151.661 103.867 1.00 147.23 ? 684 GLU A OE2 1 
ATOM 366  N N   . GLU A 1 104 ? 112.800 148.439 106.745 1.00 145.57 ? 685 GLU A N   1 
ATOM 367  C CA  . GLU A 1 104 ? 113.070 149.204 107.959 1.00 145.57 ? 685 GLU A CA  1 
ATOM 368  C C   . GLU A 1 104 ? 113.757 150.515 107.592 1.00 145.57 ? 685 GLU A C   1 
ATOM 369  O O   . GLU A 1 104 ? 114.893 150.491 107.106 1.00 145.57 ? 685 GLU A O   1 
ATOM 370  C CB  . GLU A 1 104 ? 113.930 148.386 108.916 1.00 145.57 ? 685 GLU A CB  1 
ATOM 371  C CG  . GLU A 1 104 ? 113.788 148.766 110.383 1.00 145.57 ? 685 GLU A CG  1 
ATOM 372  C CD  . GLU A 1 104 ? 114.657 147.913 111.291 1.00 145.57 ? 685 GLU A CD  1 
ATOM 373  O OE1 . GLU A 1 104 ? 115.557 147.219 110.772 1.00 145.57 ? 685 GLU A OE1 1 
ATOM 374  O OE2 . GLU A 1 104 ? 114.448 147.944 112.522 1.00 145.57 ? 685 GLU A OE2 1 
ATOM 375  N N   . PRO A 1 105 ? 113.111 151.673 107.798 1.00 146.67 ? 686 PRO A N   1 
ATOM 376  C CA  . PRO A 1 105 ? 113.629 152.923 107.223 1.00 146.67 ? 686 PRO A CA  1 
ATOM 377  C C   . PRO A 1 105 ? 114.596 153.676 108.124 1.00 146.67 ? 686 PRO A C   1 
ATOM 378  O O   . PRO A 1 105 ? 114.353 153.802 109.330 1.00 146.67 ? 686 PRO A O   1 
ATOM 379  C CB  . PRO A 1 105 ? 112.351 153.749 106.995 1.00 146.67 ? 686 PRO A CB  1 
ATOM 380  C CG  . PRO A 1 105 ? 111.196 152.766 107.181 1.00 146.67 ? 686 PRO A CG  1 
ATOM 381  C CD  . PRO A 1 105 ? 111.715 151.837 108.227 1.00 146.67 ? 686 PRO A CD  1 
ATOM 382  N N   . LEU A 1 106 ? 115.719 154.148 107.529 1.00 147.64 ? 687 LEU A N   1 
ATOM 383  C CA  . LEU A 1 106 ? 116.708 155.144 107.967 1.00 147.64 ? 687 LEU A CA  1 
ATOM 384  C C   . LEU A 1 106 ? 117.574 154.591 109.111 1.00 147.64 ? 687 LEU A C   1 
ATOM 385  O O   . LEU A 1 106 ? 117.193 153.603 109.750 1.00 147.64 ? 687 LEU A O   1 
ATOM 386  C CB  . LEU A 1 106 ? 115.944 156.446 108.307 1.00 147.64 ? 687 LEU A CB  1 
ATOM 387  C CG  . LEU A 1 106 ? 116.415 157.870 108.667 1.00 147.64 ? 687 LEU A CG  1 
ATOM 388  C CD1 . LEU A 1 106 ? 115.259 158.841 108.457 1.00 147.64 ? 687 LEU A CD1 1 
ATOM 389  C CD2 . LEU A 1 106 ? 116.963 158.037 110.074 1.00 147.64 ? 687 LEU A CD2 1 
ATOM 390  N N   . PRO A 1 107 ? 118.753 155.162 109.402 1.00 150.20 ? 688 PRO A N   1 
ATOM 391  C CA  . PRO A 1 107 ? 119.595 154.531 110.440 1.00 150.20 ? 688 PRO A CA  1 
ATOM 392  C C   . PRO A 1 107 ? 119.246 154.839 111.894 1.00 150.20 ? 688 PRO A C   1 
ATOM 393  O O   . PRO A 1 107 ? 120.158 154.831 112.730 1.00 150.20 ? 688 PRO A O   1 
ATOM 394  C CB  . PRO A 1 107 ? 121.010 155.009 110.081 1.00 150.20 ? 688 PRO A CB  1 
ATOM 395  C CG  . PRO A 1 107 ? 120.831 156.228 109.295 1.00 150.20 ? 688 PRO A CG  1 
ATOM 396  C CD  . PRO A 1 107 ? 119.577 156.001 108.506 1.00 150.20 ? 688 PRO A CD  1 
ATOM 397  N N   . HIS A 1 108 ? 117.986 155.107 112.249 1.00 149.56 ? 689 HIS A N   1 
ATOM 398  C CA  . HIS A 1 108 ? 117.611 154.834 113.631 1.00 149.56 ? 689 HIS A CA  1 
ATOM 399  C C   . HIS A 1 108 ? 116.978 153.443 113.671 1.00 149.56 ? 689 HIS A C   1 
ATOM 400  O O   . HIS A 1 108 ? 117.021 152.699 112.685 1.00 149.56 ? 689 HIS A O   1 
ATOM 401  C CB  . HIS A 1 108 ? 116.692 155.901 114.247 1.00 149.56 ? 689 HIS A CB  1 
ATOM 402  C CG  . HIS A 1 108 ? 115.355 156.040 113.587 1.00 149.56 ? 689 HIS A CG  1 
ATOM 403  N ND1 . HIS A 1 108 ? 115.113 156.957 112.586 1.00 149.56 ? 689 HIS A ND1 1 
ATOM 404  C CD2 . HIS A 1 108 ? 114.214 155.325 113.721 1.00 149.56 ? 689 HIS A CD2 1 
ATOM 405  C CE1 . HIS A 1 108 ? 113.866 156.831 112.167 1.00 149.56 ? 689 HIS A CE1 1 
ATOM 406  N NE2 . HIS A 1 108 ? 113.298 155.848 112.842 1.00 149.56 ? 689 HIS A NE2 1 
ATOM 407  N N   . GLU A 1 109 ? 116.451 153.061 114.844 1.00 146.57 ? 690 GLU A N   1 
ATOM 408  C CA  . GLU A 1 109 ? 115.726 151.833 115.228 1.00 146.57 ? 690 GLU A CA  1 
ATOM 409  C C   . GLU A 1 109 ? 116.419 150.524 114.825 1.00 146.57 ? 690 GLU A C   1 
ATOM 410  O O   . GLU A 1 109 ? 115.764 149.472 114.803 1.00 146.57 ? 690 GLU A O   1 
ATOM 411  C CB  . GLU A 1 109 ? 114.260 151.804 114.739 1.00 146.57 ? 690 GLU A CB  1 
ATOM 412  C CG  . GLU A 1 109 ? 113.973 151.748 113.234 1.00 146.57 ? 690 GLU A CG  1 
ATOM 413  C CD  . GLU A 1 109 ? 112.496 151.794 112.912 1.00 146.57 ? 690 GLU A CD  1 
ATOM 414  O OE1 . GLU A 1 109 ? 111.680 151.894 113.852 1.00 146.57 ? 690 GLU A OE1 1 
ATOM 415  O OE2 . GLU A 1 109 ? 112.154 151.726 111.712 1.00 146.57 ? 690 GLU A OE2 1 
ATOM 416  N N   . LEU A 1 110 ? 117.723 150.546 114.548 1.00 140.59 ? 691 LEU A N   1 
ATOM 417  C CA  . LEU A 1 110 ? 118.514 149.379 114.188 1.00 140.59 ? 691 LEU A CA  1 
ATOM 418  C C   . LEU A 1 110 ? 119.958 149.689 114.561 1.00 140.59 ? 691 LEU A C   1 
ATOM 419  O O   . LEU A 1 110 ? 120.435 150.799 114.307 1.00 140.59 ? 691 LEU A O   1 
ATOM 420  C CB  . LEU A 1 110 ? 118.326 149.042 112.696 1.00 140.59 ? 691 LEU A CB  1 
ATOM 421  C CG  . LEU A 1 110 ? 118.685 149.963 111.513 1.00 140.59 ? 691 LEU A CG  1 
ATOM 422  C CD1 . LEU A 1 110 ? 120.150 149.917 111.077 1.00 140.59 ? 691 LEU A CD1 1 
ATOM 423  C CD2 . LEU A 1 110 ? 117.772 149.702 110.320 1.00 140.59 ? 691 LEU A CD2 1 
ATOM 424  N N   . ARG A 1 111 ? 120.663 148.735 115.163 1.00 125.85 ? 692 ARG A N   1 
ATOM 425  C CA  . ARG A 1 111 ? 121.970 149.100 115.680 1.00 125.85 ? 692 ARG A CA  1 
ATOM 426  C C   . ARG A 1 111 ? 123.063 148.247 115.048 1.00 125.85 ? 692 ARG A C   1 
ATOM 427  O O   . ARG A 1 111 ? 122.838 147.077 114.728 1.00 125.85 ? 692 ARG A O   1 
ATOM 428  C CB  . ARG A 1 111 ? 122.037 148.947 117.206 1.00 125.85 ? 692 ARG A CB  1 
ATOM 429  C CG  . ARG A 1 111 ? 121.104 149.867 117.977 1.00 125.85 ? 692 ARG A CG  1 
ATOM 430  C CD  . ARG A 1 111 ? 120.409 149.127 119.109 1.00 125.85 ? 692 ARG A CD  1 
ATOM 431  N NE  . ARG A 1 111 ? 119.412 148.173 118.640 1.00 125.85 ? 692 ARG A NE  1 
ATOM 432  C CZ  . ARG A 1 111 ? 118.547 147.552 119.430 1.00 125.85 ? 692 ARG A CZ  1 
ATOM 433  N NH1 . ARG A 1 111 ? 118.529 147.764 120.735 1.00 125.85 ? 692 ARG A NH1 1 
ATOM 434  N NH2 . ARG A 1 111 ? 117.680 146.695 118.898 1.00 125.85 ? 692 ARG A NH2 1 
ATOM 435  N N   . PRO A 1 112 ? 124.261 148.818 114.844 1.00 125.40 ? 693 PRO A N   1 
ATOM 436  C CA  . PRO A 1 112 ? 125.423 148.016 114.426 1.00 125.40 ? 693 PRO A CA  1 
ATOM 437  C C   . PRO A 1 112 ? 125.877 147.083 115.541 1.00 125.40 ? 693 PRO A C   1 
ATOM 438  O O   . PRO A 1 112 ? 125.512 147.252 116.704 1.00 125.40 ? 693 PRO A O   1 
ATOM 439  C CB  . PRO A 1 112 ? 126.481 149.083 114.103 1.00 125.40 ? 693 PRO A CB  1 
ATOM 440  C CG  . PRO A 1 112 ? 125.997 150.336 114.749 1.00 125.40 ? 693 PRO A CG  1 
ATOM 441  C CD  . PRO A 1 112 ? 124.514 150.259 114.699 1.00 125.40 ? 693 PRO A CD  1 
ATOM 442  N N   . LEU A 1 113 ? 126.683 146.087 115.168 1.00 121.73 ? 694 LEU A N   1 
ATOM 443  C CA  . LEU A 1 113 ? 127.137 144.984 116.018 1.00 121.73 ? 694 LEU A CA  1 
ATOM 444  C C   . LEU A 1 113 ? 127.845 145.331 117.339 1.00 121.73 ? 694 LEU A C   1 
ATOM 445  O O   . LEU A 1 113 ? 127.533 144.663 118.331 1.00 121.73 ? 694 LEU A O   1 
ATOM 446  C CB  . LEU A 1 113 ? 128.021 144.042 115.188 1.00 121.73 ? 694 LEU A CB  1 
ATOM 447  C CG  . LEU A 1 113 ? 128.026 142.577 115.618 1.00 121.73 ? 694 LEU A CG  1 
ATOM 448  C CD1 . LEU A 1 113 ? 126.630 141.991 115.497 1.00 121.73 ? 694 LEU A CD1 1 
ATOM 449  C CD2 . LEU A 1 113 ? 129.016 141.783 114.782 1.00 121.73 ? 694 LEU A CD2 1 
ATOM 450  N N   . PRO A 1 114 ? 128.786 146.305 117.446 1.00 122.80 ? 695 PRO A N   1 
ATOM 451  C CA  . PRO A 1 114 ? 129.401 146.536 118.774 1.00 122.80 ? 695 PRO A CA  1 
ATOM 452  C C   . PRO A 1 114 ? 128.486 147.196 119.799 1.00 122.80 ? 695 PRO A C   1 
ATOM 453  O O   . PRO A 1 114 ? 128.564 146.868 120.993 1.00 122.80 ? 695 PRO A O   1 
ATOM 454  C CB  . PRO A 1 114 ? 130.611 147.425 118.446 1.00 122.80 ? 695 PRO A CB  1 
ATOM 455  C CG  . PRO A 1 114 ? 130.872 147.212 117.019 1.00 122.80 ? 695 PRO A CG  1 
ATOM 456  C CD  . PRO A 1 114 ? 129.517 147.098 116.433 1.00 122.80 ? 695 PRO A CD  1 
ATOM 457  N N   . VAL A 1 115 ? 127.627 148.124 119.363 1.00 125.86 ? 696 VAL A N   1 
ATOM 458  C CA  . VAL A 1 115 ? 126.628 148.729 120.244 1.00 125.86 ? 696 VAL A CA  1 
ATOM 459  C C   . VAL A 1 115 ? 125.614 147.682 120.688 1.00 125.86 ? 696 VAL A C   1 
ATOM 460  O O   . VAL A 1 115 ? 125.220 147.634 121.860 1.00 125.86 ? 696 VAL A O   1 
ATOM 461  C CB  . VAL A 1 115 ? 125.954 149.917 119.523 1.00 125.86 ? 696 VAL A CB  1 
ATOM 462  C CG1 . VAL A 1 115 ? 124.828 150.525 120.357 1.00 125.86 ? 696 VAL A CG1 1 
ATOM 463  C CG2 . VAL A 1 115 ? 126.988 150.971 119.162 1.00 125.86 ? 696 VAL A CG2 1 
ATOM 464  N N   . LEU A 1 116 ? 125.221 146.799 119.771 1.00 118.24 ? 697 LEU A N   1 
ATOM 465  C CA  . LEU A 1 116 ? 124.279 145.732 120.087 1.00 118.24 ? 697 LEU A CA  1 
ATOM 466  C C   . LEU A 1 116 ? 124.922 144.672 120.984 1.00 118.24 ? 697 LEU A C   1 
ATOM 467  O O   . LEU A 1 116 ? 124.255 144.082 121.846 1.00 118.24 ? 697 LEU A O   1 
ATOM 468  C CB  . LEU A 1 116 ? 123.755 145.158 118.766 1.00 118.24 ? 697 LEU A CB  1 
ATOM 469  C CG  . LEU A 1 116 ? 122.639 144.138 118.568 1.00 118.24 ? 697 LEU A CG  1 
ATOM 470  C CD1 . LEU A 1 116 ? 122.030 144.371 117.204 1.00 118.24 ? 697 LEU A CD1 1 
ATOM 471  C CD2 . LEU A 1 116 ? 123.222 142.755 118.583 1.00 118.24 ? 697 LEU A CD2 1 
ATOM 472  N N   . SER A 1 117 ? 126.232 144.445 120.822 1.00 119.46 ? 698 SER A N   1 
ATOM 473  C CA  . SER A 1 117 ? 126.953 143.557 121.734 1.00 119.46 ? 698 SER A CA  1 
ATOM 474  C C   . SER A 1 117 ? 127.069 144.154 123.132 1.00 119.46 ? 698 SER A C   1 
ATOM 475  O O   . SER A 1 117 ? 126.960 143.424 124.125 1.00 119.46 ? 698 SER A O   1 
ATOM 476  C CB  . SER A 1 117 ? 128.343 143.241 121.186 1.00 119.46 ? 698 SER A CB  1 
ATOM 477  O OG  . SER A 1 117 ? 129.145 142.604 122.164 1.00 119.46 ? 698 SER A OG  1 
ATOM 478  N N   . ARG A 1 118 ? 127.278 145.473 123.228 1.00 117.75 ? 699 ARG A N   1 
ATOM 479  C CA  . ARG A 1 118 ? 127.273 146.151 124.524 1.00 117.75 ? 699 ARG A CA  1 
ATOM 480  C C   . ARG A 1 118 ? 125.885 146.116 125.162 1.00 117.75 ? 699 ARG A C   1 
ATOM 481  O O   . ARG A 1 118 ? 125.768 145.978 126.389 1.00 117.75 ? 699 ARG A O   1 
ATOM 482  C CB  . ARG A 1 118 ? 127.781 147.589 124.344 1.00 117.75 ? 699 ARG A CB  1 
ATOM 483  C CG  . ARG A 1 118 ? 127.522 148.562 125.490 1.00 117.75 ? 699 ARG A CG  1 
ATOM 484  C CD  . ARG A 1 118 ? 128.065 149.947 125.174 1.00 117.75 ? 699 ARG A CD  1 
ATOM 485  N NE  . ARG A 1 118 ? 127.072 150.792 124.522 1.00 117.75 ? 699 ARG A NE  1 
ATOM 486  C CZ  . ARG A 1 118 ? 127.221 152.091 124.302 1.00 117.75 ? 699 ARG A CZ  1 
ATOM 487  N NH1 . ARG A 1 118 ? 128.318 152.734 124.670 1.00 117.75 ? 699 ARG A NH1 1 
ATOM 488  N NH2 . ARG A 1 118 ? 126.246 152.762 123.696 1.00 117.75 ? 699 ARG A NH2 1 
ATOM 489  N N   . THR A 1 119 ? 124.835 146.185 124.332 1.00 122.87 ? 700 THR A N   1 
ATOM 490  C CA  . THR A 1 119 ? 123.459 146.030 124.800 1.00 122.87 ? 700 THR A CA  1 
ATOM 491  C C   . THR A 1 119 ? 123.221 144.641 125.384 1.00 122.87 ? 700 THR A C   1 
ATOM 492  O O   . THR A 1 119 ? 122.618 144.507 126.457 1.00 122.87 ? 700 THR A O   1 
ATOM 493  C CB  . THR A 1 119 ? 122.487 146.305 123.646 1.00 122.87 ? 700 THR A CB  1 
ATOM 494  O OG1 . THR A 1 119 ? 122.676 147.641 123.165 1.00 122.87 ? 700 THR A OG1 1 
ATOM 495  C CG2 . THR A 1 119 ? 121.037 146.148 124.087 1.00 122.87 ? 700 THR A CG2 1 
ATOM 496  N N   . MET A 1 120 ? 123.737 143.603 124.715 1.00 117.33 ? 701 MET A N   1 
ATOM 497  C CA  . MET A 1 120 ? 123.608 142.237 125.225 1.00 117.33 ? 701 MET A CA  1 
ATOM 498  C C   . MET A 1 120 ? 124.421 142.031 126.501 1.00 117.33 ? 701 MET A C   1 
ATOM 499  O O   . MET A 1 120 ? 123.989 141.304 127.407 1.00 117.33 ? 701 MET A O   1 
ATOM 500  C CB  . MET A 1 120 ? 124.047 141.237 124.155 1.00 117.33 ? 701 MET A CB  1 
ATOM 501  C CG  . MET A 1 120 ? 123.944 139.728 124.495 1.00 117.33 ? 701 MET A CG  1 
ATOM 502  S SD  . MET A 1 120 ? 122.617 138.970 125.491 1.00 117.33 ? 701 MET A SD  1 
ATOM 503  C CE  . MET A 1 120 ? 121.086 139.610 124.794 1.00 117.33 ? 701 MET A CE  1 
ATOM 504  N N   . ASP A 1 121 ? 125.592 142.675 126.592 1.00 115.22 ? 702 ASP A N   1 
ATOM 505  C CA  . ASP A 1 121 ? 126.410 142.597 127.801 1.00 115.22 ? 702 ASP A CA  1 
ATOM 506  C C   . ASP A 1 121 ? 125.725 143.266 128.991 1.00 115.22 ? 702 ASP A C   1 
ATOM 507  O O   . ASP A 1 121 ? 125.742 142.732 130.107 1.00 115.22 ? 702 ASP A O   1 
ATOM 508  C CB  . ASP A 1 121 ? 127.785 143.216 127.547 1.00 115.22 ? 702 ASP A CB  1 
ATOM 509  C CG  . ASP A 1 121 ? 128.628 142.388 126.594 1.00 115.22 ? 702 ASP A CG  1 
ATOM 510  O OD1 . ASP A 1 121 ? 128.448 141.153 126.558 1.00 115.22 ? 702 ASP A OD1 1 
ATOM 511  O OD2 . ASP A 1 121 ? 129.469 142.971 125.878 1.00 115.22 ? 702 ASP A OD2 1 
ATOM 512  N N   . TYR A 1 122 ? 125.092 144.422 128.766 1.00 119.89 ? 703 TYR A N   1 
ATOM 513  C CA  . TYR A 1 122 ? 124.355 145.072 129.848 1.00 119.89 ? 703 TYR A CA  1 
ATOM 514  C C   . TYR A 1 122 ? 123.070 144.319 130.183 1.00 119.89 ? 703 TYR A C   1 
ATOM 515  O O   . TYR A 1 122 ? 122.603 144.374 131.327 1.00 119.89 ? 703 TYR A O   1 
ATOM 516  C CB  . TYR A 1 122 ? 124.053 146.529 129.486 1.00 119.89 ? 703 TYR A CB  1 
ATOM 517  C CG  . TYR A 1 122 ? 123.326 147.301 130.571 1.00 119.89 ? 703 TYR A CG  1 
ATOM 518  C CD1 . TYR A 1 122 ? 124.003 147.747 131.704 1.00 119.89 ? 703 TYR A CD1 1 
ATOM 519  C CD2 . TYR A 1 122 ? 121.963 147.575 130.467 1.00 119.89 ? 703 TYR A CD2 1 
ATOM 520  C CE1 . TYR A 1 122 ? 123.342 148.450 132.703 1.00 119.89 ? 703 TYR A CE1 1 
ATOM 521  C CE2 . TYR A 1 122 ? 121.295 148.277 131.458 1.00 119.89 ? 703 TYR A CE2 1 
ATOM 522  C CZ  . TYR A 1 122 ? 121.989 148.711 132.572 1.00 119.89 ? 703 TYR A CZ  1 
ATOM 523  O OH  . TYR A 1 122 ? 121.327 149.407 133.558 1.00 119.89 ? 703 TYR A OH  1 
ATOM 524  N N   . LEU A 1 123 ? 122.489 143.614 129.207 1.00 116.10 ? 704 LEU A N   1 
ATOM 525  C CA  . LEU A 1 123 ? 121.361 142.735 129.496 1.00 116.10 ? 704 LEU A CA  1 
ATOM 526  C C   . LEU A 1 123 ? 121.770 141.540 130.349 1.00 116.10 ? 704 LEU A C   1 
ATOM 527  O O   . LEU A 1 123 ? 120.996 141.109 131.210 1.00 116.10 ? 704 LEU A O   1 
ATOM 528  C CB  . LEU A 1 123 ? 120.708 142.256 128.198 1.00 116.10 ? 704 LEU A CB  1 
ATOM 529  C CG  . LEU A 1 123 ? 119.709 143.186 127.507 1.00 116.10 ? 704 LEU A CG  1 
ATOM 530  C CD1 . LEU A 1 123 ? 119.679 142.926 126.012 1.00 116.10 ? 704 LEU A CD1 1 
ATOM 531  C CD2 . LEU A 1 123 ? 118.323 142.988 128.100 1.00 116.10 ? 704 LEU A CD2 1 
ATOM 532  N N   . VAL A 1 124 ? 122.970 140.996 130.138 1.00 109.43 ? 705 VAL A N   1 
ATOM 533  C CA  . VAL A 1 124 ? 123.306 139.778 130.868 1.00 109.43 ? 705 VAL A CA  1 
ATOM 534  C C   . VAL A 1 124 ? 123.925 140.100 132.239 1.00 109.43 ? 705 VAL A C   1 
ATOM 535  O O   . VAL A 1 124 ? 123.771 139.317 133.186 1.00 109.43 ? 705 VAL A O   1 
ATOM 536  C CB  . VAL A 1 124 ? 124.205 138.860 130.003 1.00 109.43 ? 705 VAL A CB  1 
ATOM 537  C CG1 . VAL A 1 124 ? 125.568 139.466 129.715 1.00 109.43 ? 705 VAL A CG1 1 
ATOM 538  C CG2 . VAL A 1 124 ? 124.321 137.447 130.571 1.00 109.43 ? 705 VAL A CG2 1 
ATOM 539  N N   . THR A 1 125 ? 124.573 141.262 132.412 1.00 108.56 ? 706 THR A N   1 
ATOM 540  C CA  . THR A 1 125 ? 125.330 141.462 133.649 1.00 108.56 ? 706 THR A CA  1 
ATOM 541  C C   . THR A 1 125 ? 124.445 141.925 134.810 1.00 108.56 ? 706 THR A C   1 
ATOM 542  O O   . THR A 1 125 ? 124.784 141.698 135.977 1.00 108.56 ? 706 THR A O   1 
ATOM 543  C CB  . THR A 1 125 ? 126.505 142.431 133.431 1.00 108.56 ? 706 THR A CB  1 
ATOM 544  O OG1 . THR A 1 125 ? 127.336 142.433 134.598 1.00 108.56 ? 706 THR A OG1 1 
ATOM 545  C CG2 . THR A 1 125 ? 126.051 143.866 133.167 1.00 108.56 ? 706 THR A CG2 1 
ATOM 546  N N   . GLN A 1 126 ? 123.316 142.580 134.528 1.00 109.35 ? 707 GLN A N   1 
ATOM 547  C CA  . GLN A 1 126 ? 122.530 143.195 135.594 1.00 109.35 ? 707 GLN A CA  1 
ATOM 548  C C   . GLN A 1 126 ? 121.040 142.896 135.534 1.00 109.35 ? 707 GLN A C   1 
ATOM 549  O O   . GLN A 1 126 ? 120.412 142.727 136.583 1.00 109.35 ? 707 GLN A O   1 
ATOM 550  C CB  . GLN A 1 126 ? 122.733 144.716 135.580 1.00 109.35 ? 707 GLN A CB  1 
ATOM 551  C CG  . GLN A 1 126 ? 122.335 145.419 136.872 1.00 109.35 ? 707 GLN A CG  1 
ATOM 552  C CD  . GLN A 1 126 ? 120.940 146.010 136.816 1.00 109.35 ? 707 GLN A CD  1 
ATOM 553  O OE1 . GLN A 1 126 ? 120.506 146.504 135.777 1.00 109.35 ? 707 GLN A OE1 1 
ATOM 554  N NE2 . GLN A 1 126 ? 120.229 145.956 137.936 1.00 109.35 ? 707 GLN A NE2 1 
ATOM 555  N N   . ILE A 1 127 ? 120.458 142.834 134.333 1.00 112.04 ? 708 ILE A N   1 
ATOM 556  C CA  . ILE A 1 127 ? 119.002 142.856 134.191 1.00 112.04 ? 708 ILE A CA  1 
ATOM 557  C C   . ILE A 1 127 ? 118.388 141.513 134.572 1.00 112.04 ? 708 ILE A C   1 
ATOM 558  O O   . ILE A 1 127 ? 117.393 141.457 135.308 1.00 112.04 ? 708 ILE A O   1 
ATOM 559  C CB  . ILE A 1 127 ? 118.622 143.291 132.762 1.00 112.04 ? 708 ILE A CB  1 
ATOM 560  C CG1 . ILE A 1 127 ? 119.144 144.708 132.501 1.00 112.04 ? 708 ILE A CG1 1 
ATOM 561  C CG2 . ILE A 1 127 ? 117.124 143.184 132.513 1.00 112.04 ? 708 ILE A CG2 1 
ATOM 562  C CD1 . ILE A 1 127 ? 118.971 145.186 131.086 1.00 112.04 ? 708 ILE A CD1 1 
ATOM 563  N N   . MET A 1 128 ? 118.982 140.418 134.119 1.00 112.43 ? 709 MET A N   1 
ATOM 564  C CA  . MET A 1 128 ? 118.414 139.112 134.450 1.00 112.43 ? 709 MET A CA  1 
ATOM 565  C C   . MET A 1 128 ? 118.735 138.653 135.872 1.00 112.43 ? 709 MET A C   1 
ATOM 566  O O   . MET A 1 128 ? 118.150 137.651 136.299 1.00 112.43 ? 709 MET A O   1 
ATOM 567  C CB  . MET A 1 128 ? 118.894 138.062 133.448 1.00 112.43 ? 709 MET A CB  1 
ATOM 568  C CG  . MET A 1 128 ? 120.279 138.324 132.895 1.00 112.43 ? 709 MET A CG  1 
ATOM 569  S SD  . MET A 1 128 ? 120.728 137.145 131.612 1.00 112.43 ? 709 MET A SD  1 
ATOM 570  C CE  . MET A 1 128 ? 119.809 137.791 130.219 1.00 112.43 ? 709 MET A CE  1 
ATOM 571  N N   . ASP A 1 129 ? 119.605 139.329 136.622 1.00 117.56 ? 710 ASP A N   1 
ATOM 572  C CA  . ASP A 1 129 ? 119.965 138.923 137.974 1.00 117.56 ? 710 ASP A CA  1 
ATOM 573  C C   . ASP A 1 129 ? 119.034 139.490 139.035 1.00 117.56 ? 710 ASP A C   1 
ATOM 574  O O   . ASP A 1 129 ? 118.839 138.863 140.081 1.00 117.56 ? 710 ASP A O   1 
ATOM 575  C CB  . ASP A 1 129 ? 121.408 139.346 138.284 1.00 117.56 ? 710 ASP A CB  1 
ATOM 576  C CG  . ASP A 1 129 ? 122.426 138.322 137.831 1.00 117.56 ? 710 ASP A CG  1 
ATOM 577  O OD1 . ASP A 1 129 ? 122.155 137.612 136.841 1.00 117.56 ? 710 ASP A OD1 1 
ATOM 578  O OD2 . ASP A 1 129 ? 123.495 138.223 138.468 1.00 117.56 ? 710 ASP A OD2 1 
ATOM 579  N N   . GLN A 1 130 ? 118.458 140.668 138.794 1.00 127.50 ? 711 GLN A N   1 
ATOM 580  C CA  . GLN A 1 130 ? 117.648 141.338 139.804 1.00 127.50 ? 711 GLN A CA  1 
ATOM 581  C C   . GLN A 1 130 ? 116.286 140.670 139.952 1.00 127.50 ? 711 GLN A C   1 
ATOM 582  O O   . GLN A 1 130 ? 115.676 140.238 138.971 1.00 127.50 ? 711 GLN A O   1 
ATOM 583  C CB  . GLN A 1 130 ? 117.469 142.814 139.442 1.00 127.50 ? 711 GLN A CB  1 
ATOM 584  N N   . LYS A 1 131 ? 115.814 140.589 141.196 1.00 128.37 ? 712 LYS A N   1 
ATOM 585  C CA  . LYS A 1 131 ? 114.511 140.024 141.516 1.00 128.37 ? 712 LYS A CA  1 
ATOM 586  C C   . LYS A 1 131 ? 113.499 141.091 141.918 1.00 128.37 ? 712 LYS A C   1 
ATOM 587  O O   . LYS A 1 131 ? 112.491 140.771 142.559 1.00 128.37 ? 712 LYS A O   1 
ATOM 588  C CB  . LYS A 1 131 ? 114.647 138.981 142.625 1.00 128.37 ? 712 LYS A CB  1 
ATOM 589  N N   . GLU A 1 132 ? 113.750 142.348 141.560 1.00 125.02 ? 713 GLU A N   1 
ATOM 590  C CA  . GLU A 1 132 ? 112.838 143.434 141.899 1.00 125.02 ? 713 GLU A CA  1 
ATOM 591  C C   . GLU A 1 132 ? 111.606 143.381 141.005 1.00 125.02 ? 713 GLU A C   1 
ATOM 592  O O   . GLU A 1 132 ? 111.698 143.018 139.827 1.00 125.02 ? 713 GLU A O   1 
ATOM 593  C CB  . GLU A 1 132 ? 113.546 144.779 141.758 1.00 125.02 ? 713 GLU A CB  1 
ATOM 594  N N   . GLY A 1 133 ? 110.454 143.745 141.563 1.00 123.08 ? 714 GLY A N   1 
ATOM 595  C CA  . GLY A 1 133 ? 109.220 143.756 140.808 1.00 123.08 ? 714 GLY A CA  1 
ATOM 596  C C   . GLY A 1 133 ? 108.581 142.384 140.713 1.00 123.08 ? 714 GLY A C   1 
ATOM 597  O O   . GLY A 1 133 ? 109.056 141.389 141.262 1.00 123.08 ? 714 GLY A O   1 
ATOM 598  N N   . SER A 1 134 ? 107.465 142.344 139.991 1.00 118.70 ? 715 SER A N   1 
ATOM 599  C CA  . SER A 1 134 ? 106.740 141.099 139.803 1.00 118.70 ? 715 SER A CA  1 
ATOM 600  C C   . SER A 1 134 ? 107.424 140.230 138.752 1.00 118.70 ? 715 SER A C   1 
ATOM 601  O O   . SER A 1 134 ? 108.257 140.691 137.966 1.00 118.70 ? 715 SER A O   1 
ATOM 602  C CB  . SER A 1 134 ? 105.295 141.378 139.393 1.00 118.70 ? 715 SER A CB  1 
ATOM 603  O OG  . SER A 1 134 ? 104.680 140.213 138.873 1.00 118.70 ? 715 SER A OG  1 
ATOM 604  N N   . LEU A 1 135 ? 107.056 138.951 138.745 1.00 113.31 ? 716 LEU A N   1 
ATOM 605  C CA  . LEU A 1 135 ? 107.589 137.986 137.793 1.00 113.31 ? 716 LEU A CA  1 
ATOM 606  C C   . LEU A 1 135 ? 106.769 137.915 136.514 1.00 113.31 ? 716 LEU A C   1 
ATOM 607  O O   . LEU A 1 135 ? 107.080 137.104 135.639 1.00 113.31 ? 716 LEU A O   1 
ATOM 608  C CB  . LEU A 1 135 ? 107.666 136.592 138.428 1.00 113.31 ? 716 LEU A CB  1 
ATOM 609  C CG  . LEU A 1 135 ? 108.900 136.211 139.255 1.00 113.31 ? 716 LEU A CG  1 
ATOM 610  C CD1 . LEU A 1 135 ? 108.841 136.781 140.668 1.00 113.31 ? 716 LEU A CD1 1 
ATOM 611  C CD2 . LEU A 1 135 ? 109.065 134.703 139.295 1.00 113.31 ? 716 LEU A CD2 1 
ATOM 612  N N   . ARG A 1 136 ? 105.722 138.733 136.394 1.00 115.99 ? 717 ARG A N   1 
ATOM 613  C CA  . ARG A 1 136 ? 104.906 138.719 135.185 1.00 115.99 ? 717 ARG A CA  1 
ATOM 614  C C   . ARG A 1 136 ? 105.652 139.335 134.008 1.00 115.99 ? 717 ARG A C   1 
ATOM 615  O O   . ARG A 1 136 ? 105.662 138.772 132.908 1.00 115.99 ? 717 ARG A O   1 
ATOM 616  C CB  . ARG A 1 136 ? 103.584 139.453 135.444 1.00 115.99 ? 717 ARG A CB  1 
ATOM 617  C CG  . ARG A 1 136 ? 102.639 139.609 134.240 1.00 115.99 ? 717 ARG A CG  1 
ATOM 618  C CD  . ARG A 1 136 ? 102.653 141.024 133.641 1.00 115.99 ? 717 ARG A CD  1 
ATOM 619  N NE  . ARG A 1 136 ? 102.365 142.054 134.631 1.00 115.99 ? 717 ARG A NE  1 
ATOM 620  C CZ  . ARG A 1 136 ? 101.147 142.468 134.948 1.00 115.99 ? 717 ARG A CZ  1 
ATOM 621  N NH1 . ARG A 1 136 ? 100.073 141.969 134.359 1.00 115.99 ? 717 ARG A NH1 1 
ATOM 622  N NH2 . ARG A 1 136 ? 101.002 143.409 135.876 1.00 115.99 ? 717 ARG A NH2 1 
ATOM 623  N N   . ASP A 1 137 ? 106.285 140.486 134.223 1.00 114.27 ? 718 ASP A N   1 
ATOM 624  C CA  . ASP A 1 137 ? 106.823 141.277 133.128 1.00 114.27 ? 718 ASP A CA  1 
ATOM 625  C C   . ASP A 1 137 ? 108.311 141.071 132.884 1.00 114.27 ? 718 ASP A C   1 
ATOM 626  O O   . ASP A 1 137 ? 108.834 141.642 131.926 1.00 114.27 ? 718 ASP A O   1 
ATOM 627  C CB  . ASP A 1 137 ? 106.554 142.766 133.374 1.00 114.27 ? 718 ASP A CB  1 
ATOM 628  C CG  . ASP A 1 137 ? 107.070 143.239 134.718 1.00 114.27 ? 718 ASP A CG  1 
ATOM 629  O OD1 . ASP A 1 137 ? 107.377 142.392 135.585 1.00 114.27 ? 718 ASP A OD1 1 
ATOM 630  O OD2 . ASP A 1 137 ? 107.164 144.466 134.909 1.00 114.27 ? 718 ASP A OD2 1 
ATOM 631  N N   . TRP A 1 138 ? 108.991 140.262 133.704 1.00 109.82 ? 719 TRP A N   1 
ATOM 632  C CA  . TRP A 1 138 ? 110.414 139.994 133.497 1.00 109.82 ? 719 TRP A CA  1 
ATOM 633  C C   . TRP A 1 138 ? 110.647 139.198 132.216 1.00 109.82 ? 719 TRP A C   1 
ATOM 634  O O   . TRP A 1 138 ? 111.489 139.569 131.382 1.00 109.82 ? 719 TRP A O   1 
ATOM 635  C CB  . TRP A 1 138 ? 110.978 139.246 134.706 1.00 109.82 ? 719 TRP A CB  1 
ATOM 636  C CG  . TRP A 1 138 ? 112.448 138.980 134.634 1.00 109.82 ? 719 TRP A CG  1 
ATOM 637  C CD1 . TRP A 1 138 ? 113.453 139.897 134.716 1.00 109.82 ? 719 TRP A CD1 1 
ATOM 638  C CD2 . TRP A 1 138 ? 113.081 137.704 134.473 1.00 109.82 ? 719 TRP A CD2 1 
ATOM 639  N NE1 . TRP A 1 138 ? 114.673 139.274 134.612 1.00 109.82 ? 719 TRP A NE1 1 
ATOM 640  C CE2 . TRP A 1 138 ? 114.472 137.927 134.462 1.00 109.82 ? 719 TRP A CE2 1 
ATOM 641  C CE3 . TRP A 1 138 ? 112.606 136.396 134.335 1.00 109.82 ? 719 TRP A CE3 1 
ATOM 642  C CZ2 . TRP A 1 138 ? 115.393 136.891 134.319 1.00 109.82 ? 719 TRP A CZ2 1 
ATOM 643  C CZ3 . TRP A 1 138 ? 113.522 135.367 134.192 1.00 109.82 ? 719 TRP A CZ3 1 
ATOM 644  C CH2 . TRP A 1 138 ? 114.899 135.621 134.185 1.00 109.82 ? 719 TRP A CH2 1 
ATOM 645  N N   . TYR A 1 139 ? 109.883 138.114 132.038 1.00 111.68 ? 720 TYR A N   1 
ATOM 646  C CA  . TYR A 1 139 ? 109.961 137.316 130.818 1.00 111.68 ? 720 TYR A CA  1 
ATOM 647  C C   . TYR A 1 139 ? 109.489 138.098 129.602 1.00 111.68 ? 720 TYR A C   1 
ATOM 648  O O   . TYR A 1 139 ? 110.081 137.971 128.529 1.00 111.68 ? 720 TYR A O   1 
ATOM 649  C CB  . TYR A 1 139 ? 109.155 136.025 130.966 1.00 111.68 ? 720 TYR A CB  1 
ATOM 650  C CG  . TYR A 1 139 ? 109.222 135.136 129.742 1.00 111.68 ? 720 TYR A CG  1 
ATOM 651  C CD1 . TYR A 1 139 ? 110.359 134.385 129.465 1.00 111.68 ? 720 TYR A CD1 1 
ATOM 652  C CD2 . TYR A 1 139 ? 108.136 135.032 128.872 1.00 111.68 ? 720 TYR A CD2 1 
ATOM 653  C CE1 . TYR A 1 139 ? 110.423 133.572 128.342 1.00 111.68 ? 720 TYR A CE1 1 
ATOM 654  C CE2 . TYR A 1 139 ? 108.191 134.220 127.751 1.00 111.68 ? 720 TYR A CE2 1 
ATOM 655  C CZ  . TYR A 1 139 ? 109.335 133.492 127.494 1.00 111.68 ? 720 TYR A CZ  1 
ATOM 656  O OH  . TYR A 1 139 ? 109.395 132.681 126.384 1.00 111.68 ? 720 TYR A OH  1 
ATOM 657  N N   . ASP A 1 140 ? 108.448 138.926 129.758 1.00 115.99 ? 721 ASP A N   1 
ATOM 658  C CA  . ASP A 1 140 ? 107.954 139.746 128.651 1.00 115.99 ? 721 ASP A CA  1 
ATOM 659  C C   . ASP A 1 140 ? 108.982 140.789 128.226 1.00 115.99 ? 721 ASP A C   1 
ATOM 660  O O   . ASP A 1 140 ? 109.218 140.979 127.028 1.00 115.99 ? 721 ASP A O   1 
ATOM 661  C CB  . ASP A 1 140 ? 106.642 140.422 129.047 1.00 115.99 ? 721 ASP A CB  1 
ATOM 662  C CG  . ASP A 1 140 ? 105.449 139.491 128.941 1.00 115.99 ? 721 ASP A CG  1 
ATOM 663  O OD1 . ASP A 1 140 ? 105.639 138.262 129.050 1.00 115.99 ? 721 ASP A OD1 1 
ATOM 664  O OD2 . ASP A 1 140 ? 104.320 139.991 128.753 1.00 115.99 ? 721 ASP A OD2 1 
ATOM 665  N N   . PHE A 1 141 ? 109.649 141.410 129.206 1.00 112.51 ? 722 PHE A N   1 
ATOM 666  C CA  . PHE A 1 141 ? 110.660 142.439 128.985 1.00 112.51 ? 722 PHE A CA  1 
ATOM 667  C C   . PHE A 1 141 ? 111.866 141.872 128.241 1.00 112.51 ? 722 PHE A C   1 
ATOM 668  O O   . PHE A 1 141 ? 112.200 142.323 127.130 1.00 112.51 ? 722 PHE A O   1 
ATOM 669  C CB  . PHE A 1 141 ? 111.060 142.980 130.362 1.00 112.51 ? 722 PHE A CB  1 
ATOM 670  C CG  . PHE A 1 141 ? 112.112 144.050 130.357 1.00 112.51 ? 722 PHE A CG  1 
ATOM 671  C CD1 . PHE A 1 141 ? 112.012 145.152 129.521 1.00 112.51 ? 722 PHE A CD1 1 
ATOM 672  C CD2 . PHE A 1 141 ? 113.201 143.955 131.213 1.00 112.51 ? 722 PHE A CD2 1 
ATOM 673  C CE1 . PHE A 1 141 ? 112.973 146.154 129.561 1.00 112.51 ? 722 PHE A CE1 1 
ATOM 674  C CE2 . PHE A 1 141 ? 114.174 144.938 131.235 1.00 112.51 ? 722 PHE A CE2 1 
ATOM 675  C CZ  . PHE A 1 141 ? 114.065 146.035 130.403 1.00 112.51 ? 722 PHE A CZ  1 
ATOM 676  N N   . VAL A 1 142 ? 112.486 140.830 128.812 1.00 110.53 ? 723 VAL A N   1 
ATOM 677  C CA  . VAL A 1 142 ? 113.690 140.255 128.212 1.00 110.53 ? 723 VAL A CA  1 
ATOM 678  C C   . VAL A 1 142 ? 113.362 139.493 126.922 1.00 110.53 ? 723 VAL A C   1 
ATOM 679  O O   . VAL A 1 142 ? 114.143 139.540 125.964 1.00 110.53 ? 723 VAL A O   1 
ATOM 680  C CB  . VAL A 1 142 ? 114.432 139.381 129.246 1.00 110.53 ? 723 VAL A CB  1 
ATOM 681  C CG1 . VAL A 1 142 ? 115.792 138.942 128.723 1.00 110.53 ? 723 VAL A CG1 1 
ATOM 682  C CG2 . VAL A 1 142 ? 114.631 140.153 130.537 1.00 110.53 ? 723 VAL A CG2 1 
ATOM 683  N N   . TRP A 1 143 ? 112.198 138.827 126.850 1.00 112.73 ? 724 TRP A N   1 
ATOM 684  C CA  . TRP A 1 143 ? 111.771 138.126 125.640 1.00 112.73 ? 724 TRP A CA  1 
ATOM 685  C C   . TRP A 1 143 ? 111.509 139.077 124.482 1.00 112.73 ? 724 TRP A C   1 
ATOM 686  O O   . TRP A 1 143 ? 111.930 138.802 123.351 1.00 112.73 ? 724 TRP A O   1 
ATOM 687  C CB  . TRP A 1 143 ? 110.510 137.312 125.927 1.00 112.73 ? 724 TRP A CB  1 
ATOM 688  C CG  . TRP A 1 143 ? 110.022 136.548 124.740 1.00 112.73 ? 724 TRP A CG  1 
ATOM 689  C CD1 . TRP A 1 143 ? 110.656 135.526 124.103 1.00 112.73 ? 724 TRP A CD1 1 
ATOM 690  C CD2 . TRP A 1 143 ? 108.803 136.774 124.022 1.00 112.73 ? 724 TRP A CD2 1 
ATOM 691  N NE1 . TRP A 1 143 ? 109.900 135.086 123.042 1.00 112.73 ? 724 TRP A NE1 1 
ATOM 692  C CE2 . TRP A 1 143 ? 108.758 135.839 122.971 1.00 112.73 ? 724 TRP A CE2 1 
ATOM 693  C CE3 . TRP A 1 143 ? 107.742 137.673 124.173 1.00 112.73 ? 724 TRP A CE3 1 
ATOM 694  C CZ2 . TRP A 1 143 ? 107.694 135.775 122.074 1.00 112.73 ? 724 TRP A CZ2 1 
ATOM 695  C CZ3 . TRP A 1 143 ? 106.686 137.608 123.281 1.00 112.73 ? 724 TRP A CZ3 1 
ATOM 696  C CH2 . TRP A 1 143 ? 106.670 136.666 122.245 1.00 112.73 ? 724 TRP A CH2 1 
ATOM 697  N N   . ASN A 1 144 ? 110.826 140.199 124.749 1.00 120.13 ? 725 ASN A N   1 
ATOM 698  C CA  . ASN A 1 144 ? 110.548 141.182 123.710 1.00 120.13 ? 725 ASN A CA  1 
ATOM 699  C C   . ASN A 1 144 ? 111.833 141.836 123.229 1.00 120.13 ? 725 ASN A C   1 
ATOM 700  O O   . ASN A 1 144 ? 112.008 142.072 122.028 1.00 120.13 ? 725 ASN A O   1 
ATOM 701  C CB  . ASN A 1 144 ? 109.576 142.237 124.240 1.00 120.13 ? 725 ASN A CB  1 
ATOM 702  C CG  . ASN A 1 144 ? 108.967 143.077 123.138 1.00 120.13 ? 725 ASN A CG  1 
ATOM 703  O OD1 . ASN A 1 144 ? 109.134 142.791 121.953 1.00 120.13 ? 725 ASN A OD1 1 
ATOM 704  N ND2 . ASN A 1 144 ? 108.260 144.130 123.525 1.00 120.13 ? 725 ASN A ND2 1 
ATOM 705  N N   . ARG A 1 145 ? 112.777 142.074 124.143 1.00 122.71 ? 726 ARG A N   1 
ATOM 706  C CA  . ARG A 1 145 ? 114.014 142.723 123.722 1.00 122.71 ? 726 ARG A CA  1 
ATOM 707  C C   . ARG A 1 145 ? 114.950 141.769 122.990 1.00 122.71 ? 726 ARG A C   1 
ATOM 708  O O   . ARG A 1 145 ? 115.596 142.169 122.018 1.00 122.71 ? 726 ARG A O   1 
ATOM 709  C CB  . ARG A 1 145 ? 114.675 143.368 124.925 1.00 122.71 ? 726 ARG A CB  1 
ATOM 710  C CG  . ARG A 1 145 ? 114.278 144.793 124.942 1.00 122.71 ? 726 ARG A CG  1 
ATOM 711  C CD  . ARG A 1 145 ? 113.993 145.277 126.298 1.00 122.71 ? 726 ARG A CD  1 
ATOM 712  N NE  . ARG A 1 145 ? 113.161 146.474 126.234 1.00 122.71 ? 726 ARG A NE  1 
ATOM 713  C CZ  . ARG A 1 145 ? 111.835 146.461 126.242 1.00 122.71 ? 726 ARG A CZ  1 
ATOM 714  N NH1 . ARG A 1 145 ? 111.156 145.328 126.302 1.00 122.71 ? 726 ARG A NH1 1 
ATOM 715  N NH2 . ARG A 1 145 ? 111.173 147.612 126.162 1.00 122.71 ? 726 ARG A NH2 1 
ATOM 716  N N   . THR A 1 146 ? 114.996 140.494 123.395 1.00 117.17 ? 727 THR A N   1 
ATOM 717  C CA  . THR A 1 146 ? 115.806 139.521 122.664 1.00 117.17 ? 727 THR A CA  1 
ATOM 718  C C   . THR A 1 146 ? 115.200 139.202 121.302 1.00 117.17 ? 727 THR A C   1 
ATOM 719  O O   . THR A 1 146 ? 115.933 138.994 120.326 1.00 117.17 ? 727 THR A O   1 
ATOM 720  C CB  . THR A 1 146 ? 115.973 138.244 123.485 1.00 117.17 ? 727 THR A CB  1 
ATOM 721  O OG1 . THR A 1 146 ? 114.708 137.857 124.035 1.00 117.17 ? 727 THR A OG1 1 
ATOM 722  C CG2 . THR A 1 146 ? 116.987 138.445 124.604 1.00 117.17 ? 727 THR A CG2 1 
ATOM 723  N N   . ARG A 1 147 ? 113.866 139.204 121.204 1.00 122.14 ? 728 ARG A N   1 
ATOM 724  C CA  . ARG A 1 147 ? 113.218 139.023 119.910 1.00 122.14 ? 728 ARG A CA  1 
ATOM 725  C C   . ARG A 1 147 ? 113.413 140.259 119.035 1.00 122.14 ? 728 ARG A C   1 
ATOM 726  O O   . ARG A 1 147 ? 113.481 140.151 117.806 1.00 122.14 ? 728 ARG A O   1 
ATOM 727  C CB  . ARG A 1 147 ? 111.735 138.695 120.135 1.00 122.14 ? 728 ARG A CB  1 
ATOM 728  C CG  . ARG A 1 147 ? 110.893 138.272 118.919 1.00 122.14 ? 728 ARG A CG  1 
ATOM 729  C CD  . ARG A 1 147 ? 110.121 139.418 118.277 1.00 122.14 ? 728 ARG A CD  1 
ATOM 730  N NE  . ARG A 1 147 ? 109.267 138.970 117.183 1.00 122.14 ? 728 ARG A NE  1 
ATOM 731  C CZ  . ARG A 1 147 ? 109.671 138.813 115.930 1.00 122.14 ? 728 ARG A CZ  1 
ATOM 732  N NH1 . ARG A 1 147 ? 110.926 139.030 115.576 1.00 122.14 ? 728 ARG A NH1 1 
ATOM 733  N NH2 . ARG A 1 147 ? 108.794 138.421 115.010 1.00 122.14 ? 728 ARG A NH2 1 
ATOM 734  N N   . GLY A 1 148 ? 113.538 141.438 119.656 1.00 124.70 ? 729 GLY A N   1 
ATOM 735  C CA  . GLY A 1 148 ? 113.875 142.638 118.905 1.00 124.70 ? 729 GLY A CA  1 
ATOM 736  C C   . GLY A 1 148 ? 115.292 142.624 118.360 1.00 124.70 ? 729 GLY A C   1 
ATOM 737  O O   . GLY A 1 148 ? 115.532 143.067 117.235 1.00 124.70 ? 729 GLY A O   1 
ATOM 738  N N   . ILE A 1 149 ? 116.245 142.116 119.152 1.00 121.19 ? 730 ILE A N   1 
ATOM 739  C CA  . ILE A 1 149 ? 117.614 141.905 118.667 1.00 121.19 ? 730 ILE A CA  1 
ATOM 740  C C   . ILE A 1 149 ? 117.645 140.884 117.532 1.00 121.19 ? 730 ILE A C   1 
ATOM 741  O O   . ILE A 1 149 ? 118.339 141.083 116.523 1.00 121.19 ? 730 ILE A O   1 
ATOM 742  C CB  . ILE A 1 149 ? 118.548 141.501 119.831 1.00 121.19 ? 730 ILE A CB  1 
ATOM 743  C CG1 . ILE A 1 149 ? 118.591 142.580 120.913 1.00 121.19 ? 730 ILE A CG1 1 
ATOM 744  C CG2 . ILE A 1 149 ? 119.949 141.177 119.360 1.00 121.19 ? 730 ILE A CG2 1 
ATOM 745  C CD1 . ILE A 1 149 ? 119.113 143.912 120.431 1.00 121.19 ? 730 ILE A CD1 1 
ATOM 746  N N   . ARG A 1 150 ? 116.873 139.796 117.665 1.00 119.47 ? 731 ARG A N   1 
ATOM 747  C CA  . ARG A 1 150 ? 116.813 138.769 116.624 1.00 119.47 ? 731 ARG A CA  1 
ATOM 748  C C   . ARG A 1 150 ? 116.192 139.299 115.335 1.00 119.47 ? 731 ARG A C   1 
ATOM 749  O O   . ARG A 1 150 ? 116.678 139.001 114.237 1.00 119.47 ? 731 ARG A O   1 
ATOM 750  C CB  . ARG A 1 150 ? 116.032 137.562 117.138 1.00 119.47 ? 731 ARG A CB  1 
ATOM 751  C CG  . ARG A 1 150 ? 116.824 136.674 118.075 1.00 119.47 ? 731 ARG A CG  1 
ATOM 752  C CD  . ARG A 1 150 ? 116.099 135.371 118.313 1.00 119.47 ? 731 ARG A CD  1 
ATOM 753  N NE  . ARG A 1 150 ? 114.757 135.604 118.832 1.00 119.47 ? 731 ARG A NE  1 
ATOM 754  C CZ  . ARG A 1 150 ? 114.230 134.953 119.859 1.00 119.47 ? 731 ARG A CZ  1 
ATOM 755  N NH1 . ARG A 1 150 ? 114.897 134.001 120.489 1.00 119.47 ? 731 ARG A NH1 1 
ATOM 756  N NH2 . ARG A 1 150 ? 113.000 135.261 120.260 1.00 119.47 ? 731 ARG A NH2 1 
ATOM 757  N N   . LYS A 1 151 ? 115.149 140.126 115.453 1.00 123.03 ? 732 LYS A N   1 
ATOM 758  C CA  . LYS A 1 151 ? 114.556 140.769 114.283 1.00 123.03 ? 732 LYS A CA  1 
ATOM 759  C C   . LYS A 1 151 ? 115.493 141.825 113.707 1.00 123.03 ? 732 LYS A C   1 
ATOM 760  O O   . LYS A 1 151 ? 115.456 142.119 112.506 1.00 123.03 ? 732 LYS A O   1 
ATOM 761  C CB  . LYS A 1 151 ? 113.208 141.386 114.667 1.00 123.03 ? 732 LYS A CB  1 
ATOM 762  C CG  . LYS A 1 151 ? 112.329 141.823 113.500 1.00 123.03 ? 732 LYS A CG  1 
ATOM 763  C CD  . LYS A 1 151 ? 112.320 143.335 113.333 1.00 123.03 ? 732 LYS A CD  1 
ATOM 764  C CE  . LYS A 1 151 ? 111.447 143.752 112.163 1.00 123.03 ? 732 LYS A CE  1 
ATOM 765  N NZ  . LYS A 1 151 ? 111.470 145.225 111.946 1.00 123.03 ? 732 LYS A NZ  1 
ATOM 766  N N   . ASP A 1 152 ? 116.340 142.409 114.559 1.00 126.11 ? 733 ASP A N   1 
ATOM 767  C CA  . ASP A 1 152 ? 117.286 143.422 114.107 1.00 126.11 ? 733 ASP A CA  1 
ATOM 768  C C   . ASP A 1 152 ? 118.381 142.813 113.240 1.00 126.11 ? 733 ASP A C   1 
ATOM 769  O O   . ASP A 1 152 ? 118.688 143.332 112.162 1.00 126.11 ? 733 ASP A O   1 
ATOM 770  C CB  . ASP A 1 152 ? 117.889 144.141 115.312 1.00 126.11 ? 733 ASP A CB  1 
ATOM 771  C CG  . ASP A 1 152 ? 118.195 145.588 115.025 1.00 126.11 ? 733 ASP A CG  1 
ATOM 772  O OD1 . ASP A 1 152 ? 119.119 146.143 115.654 1.00 126.11 ? 733 ASP A OD1 1 
ATOM 773  O OD2 . ASP A 1 152 ? 117.496 146.171 114.172 1.00 126.11 ? 733 ASP A OD2 1 
ATOM 774  N N   . ILE A 1 153 ? 118.976 141.701 113.684 1.00 120.33 ? 734 ILE A N   1 
ATOM 775  C CA  . ILE A 1 153 ? 120.086 141.144 112.905 1.00 120.33 ? 734 ILE A CA  1 
ATOM 776  C C   . ILE A 1 153 ? 119.583 140.094 111.921 1.00 120.33 ? 734 ILE A C   1 
ATOM 777  O O   . ILE A 1 153 ? 120.372 139.498 111.179 1.00 120.33 ? 734 ILE A O   1 
ATOM 778  C CB  . ILE A 1 153 ? 121.192 140.568 113.810 1.00 120.33 ? 734 ILE A CB  1 
ATOM 779  C CG1 . ILE A 1 153 ? 120.634 139.578 114.824 1.00 120.33 ? 734 ILE A CG1 1 
ATOM 780  C CG2 . ILE A 1 153 ? 121.919 141.690 114.529 1.00 120.33 ? 734 ILE A CG2 1 
ATOM 781  C CD1 . ILE A 1 153 ? 121.642 138.562 115.295 1.00 120.33 ? 734 ILE A CD1 1 
ATOM 782  N N   . THR A 1 154 ? 118.272 139.826 111.917 1.00 127.17 ? 735 THR A N   1 
ATOM 783  C CA  . THR A 1 154 ? 117.710 138.934 110.904 1.00 127.17 ? 735 THR A CA  1 
ATOM 784  C C   . THR A 1 154 ? 117.724 139.589 109.526 1.00 127.17 ? 735 THR A C   1 
ATOM 785  O O   . THR A 1 154 ? 118.207 139.003 108.550 1.00 127.17 ? 735 THR A O   1 
ATOM 786  C CB  . THR A 1 154 ? 116.288 138.520 111.301 1.00 127.17 ? 735 THR A CB  1 
ATOM 787  O OG1 . THR A 1 154 ? 116.344 137.621 112.415 1.00 127.17 ? 735 THR A OG1 1 
ATOM 788  C CG2 . THR A 1 154 ? 115.566 137.825 110.150 1.00 127.17 ? 735 THR A CG2 1 
ATOM 789  N N   . GLN A 1 155 ? 117.237 140.829 109.437 1.00 130.84 ? 736 GLN A N   1 
ATOM 790  C CA  . GLN A 1 155 ? 117.152 141.488 108.138 1.00 130.84 ? 736 GLN A CA  1 
ATOM 791  C C   . GLN A 1 155 ? 118.289 142.480 107.921 1.00 130.84 ? 736 GLN A C   1 
ATOM 792  O O   . GLN A 1 155 ? 118.275 143.226 106.935 1.00 130.84 ? 736 GLN A O   1 
ATOM 793  C CB  . GLN A 1 155 ? 115.792 142.176 107.990 1.00 130.84 ? 736 GLN A CB  1 
ATOM 794  C CG  . GLN A 1 155 ? 115.298 142.910 109.234 1.00 130.84 ? 736 GLN A CG  1 
ATOM 795  C CD  . GLN A 1 155 ? 115.847 144.318 109.357 1.00 130.84 ? 736 GLN A CD  1 
ATOM 796  O OE1 . GLN A 1 155 ? 116.105 144.986 108.356 1.00 130.84 ? 736 GLN A OE1 1 
ATOM 797  N NE2 . GLN A 1 155 ? 116.022 144.779 110.589 1.00 130.84 ? 736 GLN A NE2 1 
ATOM 798  N N   . GLN A 1 156 ? 119.272 142.509 108.824 1.00 131.39 ? 737 GLN A N   1 
ATOM 799  C CA  . GLN A 1 156 ? 120.425 143.384 108.630 1.00 131.39 ? 737 GLN A CA  1 
ATOM 800  C C   . GLN A 1 156 ? 121.376 142.802 107.588 1.00 131.39 ? 737 GLN A C   1 
ATOM 801  O O   . GLN A 1 156 ? 122.041 143.550 106.857 1.00 131.39 ? 737 GLN A O   1 
ATOM 802  C CB  . GLN A 1 156 ? 121.136 143.602 109.968 1.00 131.39 ? 737 GLN A CB  1 
ATOM 803  C CG  . GLN A 1 156 ? 122.292 144.588 109.952 1.00 131.39 ? 737 GLN A CG  1 
ATOM 804  C CD  . GLN A 1 156 ? 121.860 145.994 109.586 1.00 131.39 ? 737 GLN A CD  1 
ATOM 805  O OE1 . GLN A 1 156 ? 120.800 146.459 110.005 1.00 131.39 ? 737 GLN A OE1 1 
ATOM 806  N NE2 . GLN A 1 156 ? 122.681 146.680 108.800 1.00 131.39 ? 737 GLN A NE2 1 
ATOM 807  N N   . HIS A 1 157 ? 121.423 141.465 107.498 1.00 130.77 ? 738 HIS A N   1 
ATOM 808  C CA  . HIS A 1 157 ? 122.247 140.663 106.591 1.00 130.77 ? 738 HIS A CA  1 
ATOM 809  C C   . HIS A 1 157 ? 123.739 140.956 106.710 1.00 130.77 ? 738 HIS A C   1 
ATOM 810  O O   . HIS A 1 157 ? 124.419 141.168 105.701 1.00 130.77 ? 738 HIS A O   1 
ATOM 811  C CB  . HIS A 1 157 ? 121.793 140.824 105.133 1.00 130.77 ? 738 HIS A CB  1 
ATOM 812  C CG  . HIS A 1 157 ? 120.392 140.362 104.882 1.00 130.77 ? 738 HIS A CG  1 
ATOM 813  N ND1 . HIS A 1 157 ? 120.052 139.029 104.810 1.00 130.77 ? 738 HIS A ND1 1 
ATOM 814  C CD2 . HIS A 1 157 ? 119.245 141.054 104.684 1.00 130.77 ? 738 HIS A CD2 1 
ATOM 815  C CE1 . HIS A 1 157 ? 118.756 138.919 104.580 1.00 130.77 ? 738 HIS A CE1 1 
ATOM 816  N NE2 . HIS A 1 157 ? 118.243 140.134 104.499 1.00 130.77 ? 738 HIS A NE2 1 
ATOM 817  N N   . LEU A 1 158 ? 124.254 140.973 107.937 1.00 128.27 ? 739 LEU A N   1 
ATOM 818  C CA  . LEU A 1 158 ? 125.691 140.907 108.151 1.00 128.27 ? 739 LEU A CA  1 
ATOM 819  C C   . LEU A 1 158 ? 125.964 139.761 109.113 1.00 128.27 ? 739 LEU A C   1 
ATOM 820  O O   . LEU A 1 158 ? 125.274 139.617 110.126 1.00 128.27 ? 739 LEU A O   1 
ATOM 821  C CB  . LEU A 1 158 ? 126.267 142.239 108.667 1.00 128.27 ? 739 LEU A CB  1 
ATOM 822  C CG  . LEU A 1 158 ? 125.830 142.979 109.939 1.00 128.27 ? 739 LEU A CG  1 
ATOM 823  C CD1 . LEU A 1 158 ? 126.579 142.538 111.193 1.00 128.27 ? 739 LEU A CD1 1 
ATOM 824  C CD2 . LEU A 1 158 ? 126.019 144.474 109.724 1.00 128.27 ? 739 LEU A CD2 1 
ATOM 825  N N   . CYS A 1 159 ? 126.963 138.947 108.783 1.00 133.26 ? 740 CYS A N   1 
ATOM 826  C CA  . CYS A 1 159 ? 127.248 137.726 109.518 1.00 133.26 ? 740 CYS A CA  1 
ATOM 827  C C   . CYS A 1 159 ? 128.712 137.699 109.935 1.00 133.26 ? 740 CYS A C   1 
ATOM 828  O O   . CYS A 1 159 ? 129.598 138.163 109.212 1.00 133.26 ? 740 CYS A O   1 
ATOM 829  C CB  . CYS A 1 159 ? 126.913 136.485 108.681 1.00 133.26 ? 740 CYS A CB  1 
ATOM 830  S SG  . CYS A 1 159 ? 125.147 136.275 108.346 1.00 133.26 ? 740 CYS A SG  1 
ATOM 831  N N   . ASP A 1 160 ? 128.947 137.126 111.114 1.00 132.16 ? 741 ASP A N   1 
ATOM 832  C CA  . ASP A 1 160 ? 130.249 137.070 111.764 1.00 132.16 ? 741 ASP A CA  1 
ATOM 833  C C   . ASP A 1 160 ? 130.131 136.006 112.852 1.00 132.16 ? 741 ASP A C   1 
ATOM 834  O O   . ASP A 1 160 ? 129.008 135.692 113.264 1.00 132.16 ? 741 ASP A O   1 
ATOM 835  C CB  . ASP A 1 160 ? 130.614 138.448 112.334 1.00 132.16 ? 741 ASP A CB  1 
ATOM 836  C CG  . ASP A 1 160 ? 132.020 138.507 112.893 1.00 132.16 ? 741 ASP A CG  1 
ATOM 837  O OD1 . ASP A 1 160 ? 132.975 138.539 112.089 1.00 132.16 ? 741 ASP A OD1 1 
ATOM 838  O OD2 . ASP A 1 160 ? 132.178 138.510 114.128 1.00 132.16 ? 741 ASP A OD2 1 
ATOM 839  N N   . PRO A 1 161 ? 131.234 135.387 113.300 1.00 127.59 ? 742 PRO A N   1 
ATOM 840  C CA  . PRO A 1 161 ? 131.150 134.500 114.480 1.00 127.59 ? 742 PRO A CA  1 
ATOM 841  C C   . PRO A 1 161 ? 130.700 135.168 115.777 1.00 127.59 ? 742 PRO A C   1 
ATOM 842  O O   . PRO A 1 161 ? 130.186 134.479 116.668 1.00 127.59 ? 742 PRO A O   1 
ATOM 843  C CB  . PRO A 1 161 ? 132.581 133.963 114.584 1.00 127.59 ? 742 PRO A CB  1 
ATOM 844  C CG  . PRO A 1 161 ? 133.002 133.852 113.172 1.00 127.59 ? 742 PRO A CG  1 
ATOM 845  C CD  . PRO A 1 161 ? 132.426 135.073 112.488 1.00 127.59 ? 742 PRO A CD  1 
ATOM 846  N N   . LEU A 1 162 ? 130.888 136.484 115.917 1.00 125.66 ? 743 LEU A N   1 
ATOM 847  C CA  . LEU A 1 162 ? 130.350 137.185 117.081 1.00 125.66 ? 743 LEU A CA  1 
ATOM 848  C C   . LEU A 1 162 ? 128.831 137.298 117.000 1.00 125.66 ? 743 LEU A C   1 
ATOM 849  O O   . LEU A 1 162 ? 128.150 137.336 118.031 1.00 125.66 ? 743 LEU A O   1 
ATOM 850  C CB  . LEU A 1 162 ? 130.985 138.572 117.201 1.00 125.66 ? 743 LEU A CB  1 
ATOM 851  C CG  . LEU A 1 162 ? 130.751 139.428 118.452 1.00 125.66 ? 743 LEU A CG  1 
ATOM 852  C CD1 . LEU A 1 162 ? 130.803 138.598 119.727 1.00 125.66 ? 743 LEU A CD1 1 
ATOM 853  C CD2 . LEU A 1 162 ? 131.742 140.583 118.512 1.00 125.66 ? 743 LEU A CD2 1 
ATOM 854  N N   . THR A 1 163 ? 128.285 137.353 115.779 1.00 125.03 ? 744 THR A N   1 
ATOM 855  C CA  . THR A 1 163 ? 126.838 137.435 115.584 1.00 125.03 ? 744 THR A CA  1 
ATOM 856  C C   . THR A 1 163 ? 126.157 136.125 115.983 1.00 125.03 ? 744 THR A C   1 
ATOM 857  O O   . THR A 1 163 ? 125.026 136.139 116.491 1.00 125.03 ? 744 THR A O   1 
ATOM 858  C CB  . THR A 1 163 ? 126.562 137.815 114.119 1.00 125.03 ? 744 THR A CB  1 
ATOM 859  O OG1 . THR A 1 163 ? 127.173 139.080 113.842 1.00 125.03 ? 744 THR A OG1 1 
ATOM 860  C CG2 . THR A 1 163 ? 125.071 137.948 113.806 1.00 125.03 ? 744 THR A CG2 1 
ATOM 861  N N   . VAL A 1 164 ? 126.864 135.000 115.824 1.00 119.08 ? 745 VAL A N   1 
ATOM 862  C CA  . VAL A 1 164 ? 126.371 133.688 116.241 1.00 119.08 ? 745 VAL A CA  1 
ATOM 863  C C   . VAL A 1 164 ? 126.219 133.616 117.759 1.00 119.08 ? 745 VAL A C   1 
ATOM 864  O O   . VAL A 1 164 ? 125.306 132.956 118.269 1.00 119.08 ? 745 VAL A O   1 
ATOM 865  C CB  . VAL A 1 164 ? 127.318 132.593 115.699 1.00 119.08 ? 745 VAL A CB  1 
ATOM 866  C CG1 . VAL A 1 164 ? 126.748 131.196 115.908 1.00 119.08 ? 745 VAL A CG1 1 
ATOM 867  C CG2 . VAL A 1 164 ? 127.605 132.826 114.232 1.00 119.08 ? 745 VAL A CG2 1 
ATOM 868  N N   . SER A 1 165 ? 127.074 134.334 118.502 1.00 118.44 ? 746 SER A N   1 
ATOM 869  C CA  . SER A 1 165 ? 126.973 134.368 119.961 1.00 118.44 ? 746 SER A CA  1 
ATOM 870  C C   . SER A 1 165 ? 125.718 135.096 120.430 1.00 118.44 ? 746 SER A C   1 
ATOM 871  O O   . SER A 1 165 ? 125.179 134.796 121.502 1.00 118.44 ? 746 SER A O   1 
ATOM 872  C CB  . SER A 1 165 ? 128.216 135.023 120.560 1.00 118.44 ? 746 SER A CB  1 
ATOM 873  O OG  . SER A 1 165 ? 128.317 136.375 120.159 1.00 118.44 ? 746 SER A OG  1 
ATOM 874  N N   . LEU A 1 166 ? 125.229 136.045 119.629 1.00 112.23 ? 747 LEU A N   1 
ATOM 875  C CA  . LEU A 1 166 ? 123.970 136.710 119.947 1.00 112.23 ? 747 LEU A CA  1 
ATOM 876  C C   . LEU A 1 166 ? 122.786 135.766 119.782 1.00 112.23 ? 747 LEU A C   1 
ATOM 877  O O   . LEU A 1 166 ? 121.790 135.882 120.502 1.00 112.23 ? 747 LEU A O   1 
ATOM 878  C CB  . LEU A 1 166 ? 123.785 137.954 119.076 1.00 112.23 ? 747 LEU A CB  1 
ATOM 879  C CG  . LEU A 1 166 ? 124.428 139.295 119.453 1.00 112.23 ? 747 LEU A CG  1 
ATOM 880  C CD1 . LEU A 1 166 ? 123.824 139.755 120.756 1.00 112.23 ? 747 LEU A CD1 1 
ATOM 881  C CD2 . LEU A 1 166 ? 125.952 139.322 119.532 1.00 112.23 ? 747 LEU A CD2 1 
ATOM 882  N N   . ILE A 1 167 ? 122.870 134.834 118.829 1.00 107.51 ? 748 ILE A N   1 
ATOM 883  C CA  . ILE A 1 167 ? 121.900 133.746 118.765 1.00 107.51 ? 748 ILE A CA  1 
ATOM 884  C C   . ILE A 1 167 ? 122.061 132.815 119.957 1.00 107.51 ? 748 ILE A C   1 
ATOM 885  O O   . ILE A 1 167 ? 121.053 132.358 120.518 1.00 107.51 ? 748 ILE A O   1 
ATOM 886  C CB  . ILE A 1 167 ? 122.019 132.952 117.442 1.00 107.51 ? 748 ILE A CB  1 
ATOM 887  C CG1 . ILE A 1 167 ? 122.203 133.852 116.209 1.00 107.51 ? 748 ILE A CG1 1 
ATOM 888  C CG2 . ILE A 1 167 ? 120.808 132.055 117.229 1.00 107.51 ? 748 ILE A CG2 1 
ATOM 889  C CD1 . ILE A 1 167 ? 121.108 134.909 115.995 1.00 107.51 ? 748 ILE A CD1 1 
ATOM 890  N N   . GLU A 1 168 ? 123.316 132.555 120.360 1.00 112.88 ? 749 GLU A N   1 
ATOM 891  C CA  . GLU A 1 168 ? 123.620 131.592 121.420 1.00 112.88 ? 749 GLU A CA  1 
ATOM 892  C C   . GLU A 1 168 ? 123.063 132.029 122.772 1.00 112.88 ? 749 GLU A C   1 
ATOM 893  O O   . GLU A 1 168 ? 122.475 131.222 123.502 1.00 112.88 ? 749 GLU A O   1 
ATOM 894  C CB  . GLU A 1 168 ? 125.135 131.374 121.537 1.00 112.88 ? 749 GLU A CB  1 
ATOM 895  C CG  . GLU A 1 168 ? 125.785 130.551 120.424 1.00 112.88 ? 749 GLU A CG  1 
ATOM 896  C CD  . GLU A 1 168 ? 127.247 130.869 120.212 1.00 112.88 ? 749 GLU A CD  1 
ATOM 897  O OE1 . GLU A 1 168 ? 127.724 130.727 119.070 1.00 112.88 ? 749 GLU A OE1 1 
ATOM 898  O OE2 . GLU A 1 168 ? 127.923 131.268 121.184 1.00 112.88 ? 749 GLU A OE2 1 
ATOM 899  N N   . LYS A 1 169 ? 123.223 133.311 123.112 1.00 107.73 ? 750 LYS A N   1 
ATOM 900  C CA  . LYS A 1 169 ? 122.764 133.797 124.414 1.00 107.73 ? 750 LYS A CA  1 
ATOM 901  C C   . LYS A 1 169 ? 121.240 133.851 124.486 1.00 107.73 ? 750 LYS A C   1 
ATOM 902  O O   . LYS A 1 169 ? 120.647 133.532 125.526 1.00 107.73 ? 750 LYS A O   1 
ATOM 903  C CB  . LYS A 1 169 ? 123.373 135.167 124.710 1.00 107.73 ? 750 LYS A CB  1 
ATOM 904  C CG  . LYS A 1 169 ? 124.893 135.166 124.764 1.00 107.73 ? 750 LYS A CG  1 
ATOM 905  C CD  . LYS A 1 169 ? 125.431 136.421 125.427 1.00 107.73 ? 750 LYS A CD  1 
ATOM 906  C CE  . LYS A 1 169 ? 126.940 136.359 125.586 1.00 107.73 ? 750 LYS A CE  1 
ATOM 907  N NZ  . LYS A 1 169 ? 127.626 136.083 124.294 1.00 107.73 ? 750 LYS A NZ  1 
ATOM 908  N N   . CYS A 1 170 ? 120.589 134.212 123.375 1.00 110.46 ? 751 CYS A N   1 
ATOM 909  C CA  . CYS A 1 170 ? 119.129 134.248 123.339 1.00 110.46 ? 751 CYS A CA  1 
ATOM 910  C C   . CYS A 1 170 ? 118.524 132.850 123.400 1.00 110.46 ? 751 CYS A C   1 
ATOM 911  O O   . CYS A 1 170 ? 117.511 132.635 124.082 1.00 110.46 ? 751 CYS A O   1 
ATOM 912  C CB  . CYS A 1 170 ? 118.649 134.987 122.089 1.00 110.46 ? 751 CYS A CB  1 
ATOM 913  S SG  . CYS A 1 170 ? 119.074 136.742 122.051 1.00 110.46 ? 751 CYS A SG  1 
ATOM 914  N N   . THR A 1 171 ? 119.139 131.872 122.721 1.00 98.20  ? 752 THR A N   1 
ATOM 915  C CA  . THR A 1 171 ? 118.586 130.525 122.807 1.00 98.20  ? 752 THR A CA  1 
ATOM 916  C C   . THR A 1 171 ? 118.916 129.879 124.150 1.00 98.20  ? 752 THR A C   1 
ATOM 917  O O   . THR A 1 171 ? 118.140 129.054 124.636 1.00 98.20  ? 752 THR A O   1 
ATOM 918  C CB  . THR A 1 171 ? 119.028 129.642 121.627 1.00 98.20  ? 752 THR A CB  1 
ATOM 919  O OG1 . THR A 1 171 ? 118.308 128.404 121.674 1.00 98.20  ? 752 THR A OG1 1 
ATOM 920  C CG2 . THR A 1 171 ? 120.507 129.315 121.648 1.00 98.20  ? 752 THR A CG2 1 
ATOM 921  N N   . ARG A 1 172 ? 120.014 130.291 124.806 1.00 98.29  ? 753 ARG A N   1 
ATOM 922  C CA  . ARG A 1 172 ? 120.271 129.823 126.168 1.00 98.29  ? 753 ARG A CA  1 
ATOM 923  C C   . ARG A 1 172 ? 119.268 130.409 127.155 1.00 98.29  ? 753 ARG A C   1 
ATOM 924  O O   . ARG A 1 172 ? 118.843 129.723 128.096 1.00 98.29  ? 753 ARG A O   1 
ATOM 925  C CB  . ARG A 1 172 ? 121.696 130.167 126.596 1.00 98.29  ? 753 ARG A CB  1 
ATOM 926  C CG  . ARG A 1 172 ? 122.756 129.191 126.128 1.00 98.29  ? 753 ARG A CG  1 
ATOM 927  C CD  . ARG A 1 172 ? 124.143 129.762 126.358 1.00 98.29  ? 753 ARG A CD  1 
ATOM 928  N NE  . ARG A 1 172 ? 125.196 128.932 125.787 1.00 98.29  ? 753 ARG A NE  1 
ATOM 929  C CZ  . ARG A 1 172 ? 126.475 129.279 125.735 1.00 98.29  ? 753 ARG A CZ  1 
ATOM 930  N NH1 . ARG A 1 172 ? 126.897 130.437 126.216 1.00 98.29  ? 753 ARG A NH1 1 
ATOM 931  N NH2 . ARG A 1 172 ? 127.351 128.446 125.181 1.00 98.29  ? 753 ARG A NH2 1 
ATOM 932  N N   . PHE A 1 173 ? 118.869 131.668 126.939 1.00 99.16  ? 754 PHE A N   1 
ATOM 933  C CA  . PHE A 1 173 ? 117.788 132.277 127.707 1.00 99.16  ? 754 PHE A CA  1 
ATOM 934  C C   . PHE A 1 173 ? 116.463 131.551 127.502 1.00 99.16  ? 754 PHE A C   1 
ATOM 935  O O   . PHE A 1 173 ? 115.725 131.348 128.474 1.00 99.16  ? 754 PHE A O   1 
ATOM 936  C CB  . PHE A 1 173 ? 117.644 133.752 127.317 1.00 99.16  ? 754 PHE A CB  1 
ATOM 937  C CG  . PHE A 1 173 ? 116.456 134.434 127.933 1.00 99.16  ? 754 PHE A CG  1 
ATOM 938  C CD1 . PHE A 1 173 ? 116.442 134.728 129.289 1.00 99.16  ? 754 PHE A CD1 1 
ATOM 939  C CD2 . PHE A 1 173 ? 115.353 134.779 127.160 1.00 99.16  ? 754 PHE A CD2 1 
ATOM 940  C CE1 . PHE A 1 173 ? 115.356 135.362 129.864 1.00 99.16  ? 754 PHE A CE1 1 
ATOM 941  C CE2 . PHE A 1 173 ? 114.257 135.404 127.730 1.00 99.16  ? 754 PHE A CE2 1 
ATOM 942  C CZ  . PHE A 1 173 ? 114.257 135.689 129.085 1.00 99.16  ? 754 PHE A CZ  1 
ATOM 943  N N   . HIS A 1 174 ? 116.166 131.139 126.265 1.00 97.29  ? 755 HIS A N   1 
ATOM 944  C CA  . HIS A 1 174 ? 114.956 130.363 125.995 1.00 97.29  ? 755 HIS A CA  1 
ATOM 945  C C   . HIS A 1 174 ? 114.988 128.967 126.618 1.00 97.29  ? 755 HIS A C   1 
ATOM 946  O O   . HIS A 1 174 ? 113.952 128.504 127.113 1.00 97.29  ? 755 HIS A O   1 
ATOM 947  C CB  . HIS A 1 174 ? 114.723 130.262 124.489 1.00 97.29  ? 755 HIS A CB  1 
ATOM 948  C CG  . HIS A 1 174 ? 113.891 131.375 123.936 1.00 97.29  ? 755 HIS A CG  1 
ATOM 949  N ND1 . HIS A 1 174 ? 112.517 131.400 124.042 1.00 97.29  ? 755 HIS A ND1 1 
ATOM 950  C CD2 . HIS A 1 174 ? 114.239 132.511 123.286 1.00 97.29  ? 755 HIS A CD2 1 
ATOM 951  C CE1 . HIS A 1 174 ? 112.054 132.497 123.472 1.00 97.29  ? 755 HIS A CE1 1 
ATOM 952  N NE2 . HIS A 1 174 ? 113.078 133.189 123.006 1.00 97.29  ? 755 HIS A NE2 1 
ATOM 953  N N   . ILE A 1 175 ? 116.151 128.297 126.610 1.00 96.61  ? 756 ILE A N   1 
ATOM 954  C CA  . ILE A 1 175 ? 116.290 126.995 127.270 1.00 96.61  ? 756 ILE A CA  1 
ATOM 955  C C   . ILE A 1 175 ? 116.100 127.133 128.781 1.00 96.61  ? 756 ILE A C   1 
ATOM 956  O O   . ILE A 1 175 ? 115.396 126.324 129.405 1.00 96.61  ? 756 ILE A O   1 
ATOM 957  C CB  . ILE A 1 175 ? 117.650 126.346 126.922 1.00 96.61  ? 756 ILE A CB  1 
ATOM 958  C CG1 . ILE A 1 175 ? 117.743 125.974 125.436 1.00 96.61  ? 756 ILE A CG1 1 
ATOM 959  C CG2 . ILE A 1 175 ? 117.923 125.107 127.768 1.00 96.61  ? 756 ILE A CG2 1 
ATOM 960  C CD1 . ILE A 1 175 ? 116.993 124.755 125.013 1.00 96.61  ? 756 ILE A CD1 1 
ATOM 961  N N   . HIS A 1 176 ? 116.679 128.180 129.382 1.00 97.00  ? 757 HIS A N   1 
ATOM 962  C CA  . HIS A 1 176 ? 116.513 128.432 130.812 1.00 97.00  ? 757 HIS A CA  1 
ATOM 963  C C   . HIS A 1 176 ? 115.078 128.779 131.200 1.00 97.00  ? 757 HIS A C   1 
ATOM 964  O O   . HIS A 1 176 ? 114.588 128.319 132.236 1.00 97.00  ? 757 HIS A O   1 
ATOM 965  C CB  . HIS A 1 176 ? 117.436 129.556 131.282 1.00 97.00  ? 757 HIS A CB  1 
ATOM 966  C CG  . HIS A 1 176 ? 117.290 129.871 132.737 1.00 97.00  ? 757 HIS A CG  1 
ATOM 967  N ND1 . HIS A 1 176 ? 117.155 128.891 133.697 1.00 97.00  ? 757 HIS A ND1 1 
ATOM 968  C CD2 . HIS A 1 176 ? 117.217 131.053 133.393 1.00 97.00  ? 757 HIS A CD2 1 
ATOM 969  C CE1 . HIS A 1 176 ? 117.025 129.455 134.884 1.00 97.00  ? 757 HIS A CE1 1 
ATOM 970  N NE2 . HIS A 1 176 ? 117.056 130.766 134.727 1.00 97.00  ? 757 HIS A NE2 1 
ATOM 971  N N   . CYS A 1 177 ? 114.390 129.578 130.386 1.00 102.61 ? 758 CYS A N   1 
ATOM 972  C CA  . CYS A 1 177 ? 113.002 129.910 130.676 1.00 102.61 ? 758 CYS A CA  1 
ATOM 973  C C   . CYS A 1 177 ? 112.005 128.851 130.244 1.00 102.61 ? 758 CYS A C   1 
ATOM 974  O O   . CYS A 1 177 ? 110.825 128.978 130.571 1.00 102.61 ? 758 CYS A O   1 
ATOM 975  C CB  . CYS A 1 177 ? 112.616 131.243 130.030 1.00 102.61 ? 758 CYS A CB  1 
ATOM 976  S SG  . CYS A 1 177 ? 113.295 132.666 130.886 1.00 102.61 ? 758 CYS A SG  1 
ATOM 977  N N   . ALA A 1 178 ? 112.442 127.815 129.521 1.00 94.03  ? 759 ALA A N   1 
ATOM 978  C CA  . ALA A 1 178 ? 111.558 126.691 129.227 1.00 94.03  ? 759 ALA A CA  1 
ATOM 979  C C   . ALA A 1 178 ? 111.196 125.879 130.468 1.00 94.03  ? 759 ALA A C   1 
ATOM 980  O O   . ALA A 1 178 ? 110.171 125.187 130.466 1.00 94.03  ? 759 ALA A O   1 
ATOM 981  C CB  . ALA A 1 178 ? 112.208 125.782 128.182 1.00 94.03  ? 759 ALA A CB  1 
ATOM 982  N N   . HIS A 1 179 ? 112.009 125.945 131.525 1.00 100.11 ? 760 HIS A N   1 
ATOM 983  C CA  . HIS A 1 179 ? 111.734 125.258 132.777 1.00 100.11 ? 760 HIS A CA  1 
ATOM 984  C C   . HIS A 1 179 ? 111.384 126.191 133.926 1.00 100.11 ? 760 HIS A C   1 
ATOM 985  O O   . HIS A 1 179 ? 110.492 125.854 134.716 1.00 100.11 ? 760 HIS A O   1 
ATOM 986  C CB  . HIS A 1 179 ? 112.943 124.394 133.180 1.00 100.11 ? 760 HIS A CB  1 
ATOM 987  C CG  . HIS A 1 179 ? 112.974 124.019 134.630 1.00 100.11 ? 760 HIS A CG  1 
ATOM 988  N ND1 . HIS A 1 179 ? 113.943 124.480 135.495 1.00 100.11 ? 760 HIS A ND1 1 
ATOM 989  C CD2 . HIS A 1 179 ? 112.156 123.232 135.367 1.00 100.11 ? 760 HIS A CD2 1 
ATOM 990  C CE1 . HIS A 1 179 ? 113.722 123.990 136.702 1.00 100.11 ? 760 HIS A CE1 1 
ATOM 991  N NE2 . HIS A 1 179 ? 112.643 123.229 136.652 1.00 100.11 ? 760 HIS A NE2 1 
ATOM 992  N N   . PHE A 1 180 ? 112.037 127.356 134.024 1.00 104.13 ? 761 PHE A N   1 
ATOM 993  C CA  . PHE A 1 180 ? 111.913 128.209 135.206 1.00 104.13 ? 761 PHE A CA  1 
ATOM 994  C C   . PHE A 1 180 ? 110.534 128.849 135.308 1.00 104.13 ? 761 PHE A C   1 
ATOM 995  O O   . PHE A 1 180 ? 110.000 129.013 136.411 1.00 104.13 ? 761 PHE A O   1 
ATOM 996  C CB  . PHE A 1 180 ? 112.994 129.288 135.184 1.00 104.13 ? 761 PHE A CB  1 
ATOM 997  C CG  . PHE A 1 180 ? 113.056 130.112 136.438 1.00 104.13 ? 761 PHE A CG  1 
ATOM 998  C CD1 . PHE A 1 180 ? 112.930 129.515 137.687 1.00 104.13 ? 761 PHE A CD1 1 
ATOM 999  C CD2 . PHE A 1 180 ? 113.245 131.485 136.368 1.00 104.13 ? 761 PHE A CD2 1 
ATOM 1000 C CE1 . PHE A 1 180 ? 112.985 130.276 138.845 1.00 104.13 ? 761 PHE A CE1 1 
ATOM 1001 C CE2 . PHE A 1 180 ? 113.306 132.252 137.520 1.00 104.13 ? 761 PHE A CE2 1 
ATOM 1002 C CZ  . PHE A 1 180 ? 113.175 131.646 138.759 1.00 104.13 ? 761 PHE A CZ  1 
ATOM 1003 N N   . MET A 1 181 ? 109.935 129.201 134.174 1.00 106.13 ? 762 MET A N   1 
ATOM 1004 C CA  . MET A 1 181 ? 108.665 129.911 134.164 1.00 106.13 ? 762 MET A CA  1 
ATOM 1005 C C   . MET A 1 181 ? 107.498 128.985 133.847 1.00 106.13 ? 762 MET A C   1 
ATOM 1006 O O   . MET A 1 181 ? 106.471 129.429 133.332 1.00 106.13 ? 762 MET A O   1 
ATOM 1007 C CB  . MET A 1 181 ? 108.710 131.061 133.162 1.00 106.13 ? 762 MET A CB  1 
ATOM 1008 C CG  . MET A 1 181 ? 109.235 132.338 133.770 1.00 106.13 ? 762 MET A CG  1 
ATOM 1009 S SD  . MET A 1 181 ? 108.004 133.328 134.627 1.00 106.13 ? 762 MET A SD  1 
ATOM 1010 C CE  . MET A 1 181 ? 109.079 134.476 135.485 1.00 106.13 ? 762 MET A CE  1 
ATOM 1011 N N   . CYS A 1 182 ? 107.642 127.697 134.162 1.00 109.19 ? 763 CYS A N   1 
ATOM 1012 C CA  . CYS A 1 182 ? 106.598 126.724 133.867 1.00 109.19 ? 763 CYS A CA  1 
ATOM 1013 C C   . CYS A 1 182 ? 105.422 126.818 134.829 1.00 109.19 ? 763 CYS A C   1 
ATOM 1014 O O   . CYS A 1 182 ? 104.302 126.458 134.450 1.00 109.19 ? 763 CYS A O   1 
ATOM 1015 C CB  . CYS A 1 182 ? 107.192 125.313 133.892 1.00 109.19 ? 763 CYS A CB  1 
ATOM 1016 S SG  . CYS A 1 182 ? 106.104 124.005 133.276 1.00 109.19 ? 763 CYS A SG  1 
ATOM 1017 N N   . GLU A 1 183 ? 105.635 127.318 136.045 1.00 106.94 ? 764 GLU A N   1 
ATOM 1018 C CA  . GLU A 1 183 ? 104.575 127.373 137.047 1.00 106.94 ? 764 GLU A CA  1 
ATOM 1019 C C   . GLU A 1 183 ? 103.732 128.641 136.920 1.00 106.94 ? 764 GLU A C   1 
ATOM 1020 O O   . GLU A 1 183 ? 102.788 128.840 137.690 1.00 106.94 ? 764 GLU A O   1 
ATOM 1021 C CB  . GLU A 1 183 ? 105.177 127.267 138.452 1.00 106.94 ? 764 GLU A CB  1 
ATOM 1022 N N   . GLU A 1 184 ? 104.080 129.514 135.970 1.00 106.27 ? 765 GLU A N   1 
ATOM 1023 C CA  . GLU A 1 184 ? 103.356 130.755 135.715 1.00 106.27 ? 765 GLU A CA  1 
ATOM 1024 C C   . GLU A 1 184 ? 101.964 130.468 135.162 1.00 106.27 ? 765 GLU A C   1 
ATOM 1025 O O   . GLU A 1 184 ? 101.800 129.578 134.318 1.00 106.27 ? 765 GLU A O   1 
ATOM 1026 C CB  . GLU A 1 184 ? 104.139 131.643 134.747 1.00 106.27 ? 765 GLU A CB  1 
ATOM 1027 N N   . PRO A 1 185 ? 100.941 131.193 135.616 1.00 114.76 ? 766 PRO A N   1 
ATOM 1028 C CA  . PRO A 1 185 ? 99.572  130.875 135.191 1.00 114.76 ? 766 PRO A CA  1 
ATOM 1029 C C   . PRO A 1 185 ? 99.208  131.464 133.837 1.00 114.76 ? 766 PRO A C   1 
ATOM 1030 O O   . PRO A 1 185 ? 99.145  132.690 133.691 1.00 114.76 ? 766 PRO A O   1 
ATOM 1031 C CB  . PRO A 1 185 ? 98.713  131.473 136.312 1.00 114.76 ? 766 PRO A CB  1 
ATOM 1032 N N   . MET A 1 186 ? 98.945  130.566 132.874 1.00 117.72 ? 767 MET A N   1 
ATOM 1033 C CA  . MET A 1 186 ? 98.468  130.751 131.495 1.00 117.72 ? 767 MET A CA  1 
ATOM 1034 C C   . MET A 1 186 ? 98.808  132.047 130.756 1.00 117.72 ? 767 MET A C   1 
ATOM 1035 O O   . MET A 1 186 ? 99.471  132.013 129.714 1.00 117.72 ? 767 MET A O   1 
ATOM 1036 C CB  . MET A 1 186 ? 96.946  130.588 131.479 1.00 117.72 ? 767 MET A CB  1 
ATOM 1037 N N   . SER A 1 187 ? 98.349  133.186 131.279 1.00 115.31 ? 768 SER A N   1 
ATOM 1038 C CA  . SER A 1 187 ? 98.447  134.442 130.539 1.00 115.31 ? 768 SER A CA  1 
ATOM 1039 C C   . SER A 1 187 ? 99.858  135.016 130.590 1.00 115.31 ? 768 SER A C   1 
ATOM 1040 O O   . SER A 1 187 ? 100.236 135.839 129.749 1.00 115.31 ? 768 SER A O   1 
ATOM 1041 C CB  . SER A 1 187 ? 97.437  135.449 131.090 1.00 115.31 ? 768 SER A CB  1 
ATOM 1042 O OG  . SER A 1 187 ? 97.771  135.833 132.412 1.00 115.31 ? 768 SER A OG  1 
ATOM 1043 N N   . SER A 1 188 ? 100.655 134.595 131.573 1.00 111.20 ? 769 SER A N   1 
ATOM 1044 C CA  . SER A 1 188 ? 101.971 135.190 131.766 1.00 111.20 ? 769 SER A CA  1 
ATOM 1045 C C   . SER A 1 188 ? 103.059 134.540 130.922 1.00 111.20 ? 769 SER A C   1 
ATOM 1046 O O   . SER A 1 188 ? 103.949 135.249 130.440 1.00 111.20 ? 769 SER A O   1 
ATOM 1047 C CB  . SER A 1 188 ? 102.367 135.125 133.241 1.00 111.20 ? 769 SER A CB  1 
ATOM 1048 O OG  . SER A 1 188 ? 101.517 135.939 134.029 1.00 111.20 ? 769 SER A OG  1 
ATOM 1049 N N   . PHE A 1 189 ? 103.018 133.222 130.726 1.00 108.21 ? 770 PHE A N   1 
ATOM 1050 C CA  . PHE A 1 189 ? 104.101 132.530 130.041 1.00 108.21 ? 770 PHE A CA  1 
ATOM 1051 C C   . PHE A 1 189 ? 103.711 132.089 128.636 1.00 108.21 ? 770 PHE A C   1 
ATOM 1052 O O   . PHE A 1 189 ? 104.404 132.469 127.684 1.00 108.21 ? 770 PHE A O   1 
ATOM 1053 C CB  . PHE A 1 189 ? 104.578 131.323 130.860 1.00 108.21 ? 770 PHE A CB  1 
ATOM 1054 C CG  . PHE A 1 189 ? 105.774 130.628 130.268 1.00 108.21 ? 770 PHE A CG  1 
ATOM 1055 C CD1 . PHE A 1 189 ? 106.850 131.367 129.784 1.00 108.21 ? 770 PHE A CD1 1 
ATOM 1056 C CD2 . PHE A 1 189 ? 105.822 129.244 130.186 1.00 108.21 ? 770 PHE A CD2 1 
ATOM 1057 C CE1 . PHE A 1 189 ? 107.950 130.738 129.233 1.00 108.21 ? 770 PHE A CE1 1 
ATOM 1058 C CE2 . PHE A 1 189 ? 106.928 128.608 129.644 1.00 108.21 ? 770 PHE A CE2 1 
ATOM 1059 C CZ  . PHE A 1 189 ? 107.984 129.358 129.160 1.00 108.21 ? 770 PHE A CZ  1 
ATOM 1060 N N   . ASP A 1 190 ? 102.629 131.301 128.498 1.00 108.97 ? 771 ASP A N   1 
ATOM 1061 C CA  . ASP A 1 190 ? 102.126 130.740 127.239 1.00 108.97 ? 771 ASP A CA  1 
ATOM 1062 C C   . ASP A 1 190 ? 103.190 129.895 126.543 1.00 108.97 ? 771 ASP A C   1 
ATOM 1063 O O   . ASP A 1 190 ? 103.785 130.342 125.562 1.00 108.97 ? 771 ASP A O   1 
ATOM 1064 C CB  . ASP A 1 190 ? 101.579 131.832 126.304 1.00 108.97 ? 771 ASP A CB  1 
ATOM 1065 C CG  . ASP A 1 190 ? 100.435 131.343 125.433 1.00 108.97 ? 771 ASP A CG  1 
ATOM 1066 O OD1 . ASP A 1 190 ? 100.376 130.131 125.136 1.00 108.97 ? 771 ASP A OD1 1 
ATOM 1067 O OD2 . ASP A 1 190 ? 99.584  132.174 125.052 1.00 108.97 ? 771 ASP A OD2 1 
ATOM 1068 N N   . ALA A 1 191 ? 103.464 128.699 127.086 1.00 105.78 ? 772 ALA A N   1 
ATOM 1069 C CA  . ALA A 1 191 ? 104.612 127.872 126.694 1.00 105.78 ? 772 ALA A CA  1 
ATOM 1070 C C   . ALA A 1 191 ? 104.579 127.423 125.231 1.00 105.78 ? 772 ALA A C   1 
ATOM 1071 O O   . ALA A 1 191 ? 105.612 127.027 124.675 1.00 105.78 ? 772 ALA A O   1 
ATOM 1072 C CB  . ALA A 1 191 ? 104.686 126.644 127.604 1.00 105.78 ? 772 ALA A CB  1 
ATOM 1073 N N   . LYS A 1 192 ? 103.395 127.453 124.603 1.00 103.21 ? 773 LYS A N   1 
ATOM 1074 C CA  . LYS A 1 192 ? 103.262 127.113 123.189 1.00 103.21 ? 773 LYS A CA  1 
ATOM 1075 C C   . LYS A 1 192 ? 104.020 128.091 122.293 1.00 103.21 ? 773 LYS A C   1 
ATOM 1076 O O   . LYS A 1 192 ? 104.736 127.669 121.380 1.00 103.21 ? 773 LYS A O   1 
ATOM 1077 C CB  . LYS A 1 192 ? 101.780 127.074 122.804 1.00 103.21 ? 773 LYS A CB  1 
ATOM 1078 C CG  . LYS A 1 192 ? 101.490 126.881 121.315 1.00 103.21 ? 773 LYS A CG  1 
ATOM 1079 C CD  . LYS A 1 192 ? 102.105 125.601 120.750 1.00 103.21 ? 773 LYS A CD  1 
ATOM 1080 C CE  . LYS A 1 192 ? 101.190 124.975 119.714 1.00 103.21 ? 773 LYS A CE  1 
ATOM 1081 N NZ  . LYS A 1 192 ? 100.599 126.013 118.824 1.00 103.21 ? 773 LYS A NZ  1 
ATOM 1082 N N   . ILE A 1 193 ? 103.913 129.398 122.560 1.00 104.08 ? 774 ILE A N   1 
ATOM 1083 C CA  . ILE A 1 193 ? 104.600 130.361 121.700 1.00 104.08 ? 774 ILE A CA  1 
ATOM 1084 C C   . ILE A 1 193 ? 106.090 130.407 122.053 1.00 104.08 ? 774 ILE A C   1 
ATOM 1085 O O   . ILE A 1 193 ? 106.930 130.733 121.209 1.00 104.08 ? 774 ILE A O   1 
ATOM 1086 C CB  . ILE A 1 193 ? 103.912 131.747 121.767 1.00 104.08 ? 774 ILE A CB  1 
ATOM 1087 C CG1 . ILE A 1 193 ? 104.424 132.701 120.683 1.00 104.08 ? 774 ILE A CG1 1 
ATOM 1088 C CG2 . ILE A 1 193 ? 104.154 132.444 123.086 1.00 104.08 ? 774 ILE A CG2 1 
ATOM 1089 C CD1 . ILE A 1 193 ? 103.570 133.937 120.504 1.00 104.08 ? 774 ILE A CD1 1 
ATOM 1090 N N   . ASN A 1 194 ? 106.452 129.976 123.269 1.00 101.48 ? 775 ASN A N   1 
ATOM 1091 C CA  . ASN A 1 194 ? 107.864 129.855 123.632 1.00 101.48 ? 775 ASN A CA  1 
ATOM 1092 C C   . ASN A 1 194 ? 108.527 128.688 122.905 1.00 101.48 ? 775 ASN A C   1 
ATOM 1093 O O   . ASN A 1 194 ? 109.630 128.827 122.356 1.00 101.48 ? 775 ASN A O   1 
ATOM 1094 C CB  . ASN A 1 194 ? 108.003 129.691 125.145 1.00 101.48 ? 775 ASN A CB  1 
ATOM 1095 C CG  . ASN A 1 194 ? 109.438 129.478 125.578 1.00 101.48 ? 775 ASN A CG  1 
ATOM 1096 O OD1 . ASN A 1 194 ? 110.247 130.405 125.568 1.00 101.48 ? 775 ASN A OD1 1 
ATOM 1097 N ND2 . ASN A 1 194 ? 109.763 128.249 125.962 1.00 101.48 ? 775 ASN A ND2 1 
ATOM 1098 N N   . ASN A 1 195 ? 107.851 127.534 122.868 1.00 103.51 ? 776 ASN A N   1 
ATOM 1099 C CA  . ASN A 1 195 ? 108.364 126.388 122.121 1.00 103.51 ? 776 ASN A CA  1 
ATOM 1100 C C   . ASN A 1 195 ? 108.280 126.628 120.618 1.00 103.51 ? 776 ASN A C   1 
ATOM 1101 O O   . ASN A 1 195 ? 109.048 126.046 119.843 1.00 103.51 ? 776 ASN A O   1 
ATOM 1102 C CB  . ASN A 1 195 ? 107.594 125.126 122.509 1.00 103.51 ? 776 ASN A CB  1 
ATOM 1103 C CG  . ASN A 1 195 ? 108.317 123.854 122.113 1.00 103.51 ? 776 ASN A CG  1 
ATOM 1104 O OD1 . ASN A 1 195 ? 109.503 123.875 121.785 1.00 103.51 ? 776 ASN A OD1 1 
ATOM 1105 N ND2 . ASN A 1 195 ? 107.602 122.736 122.140 1.00 103.51 ? 776 ASN A ND2 1 
ATOM 1106 N N   . GLU A 1 196 ? 107.344 127.480 120.188 1.00 111.32 ? 777 GLU A N   1 
ATOM 1107 C CA  . GLU A 1 196 ? 107.304 127.920 118.800 1.00 111.32 ? 777 GLU A CA  1 
ATOM 1108 C C   . GLU A 1 196 ? 108.477 128.833 118.469 1.00 111.32 ? 777 GLU A C   1 
ATOM 1109 O O   . GLU A 1 196 ? 109.049 128.730 117.383 1.00 111.32 ? 777 GLU A O   1 
ATOM 1110 C CB  . GLU A 1 196 ? 105.974 128.630 118.532 1.00 111.32 ? 777 GLU A CB  1 
ATOM 1111 C CG  . GLU A 1 196 ? 105.774 129.125 117.110 1.00 111.32 ? 777 GLU A CG  1 
ATOM 1112 C CD  . GLU A 1 196 ? 104.398 129.725 116.894 1.00 111.32 ? 777 GLU A CD  1 
ATOM 1113 O OE1 . GLU A 1 196 ? 104.059 130.707 117.589 1.00 111.32 ? 777 GLU A OE1 1 
ATOM 1114 O OE2 . GLU A 1 196 ? 103.656 129.216 116.029 1.00 111.32 ? 777 GLU A OE2 1 
ATOM 1115 N N   . ASN A 1 197 ? 108.855 129.715 119.395 1.00 105.31 ? 778 ASN A N   1 
ATOM 1116 C CA  . ASN A 1 197 ? 109.900 130.698 119.133 1.00 105.31 ? 778 ASN A CA  1 
ATOM 1117 C C   . ASN A 1 197 ? 111.274 130.033 119.174 1.00 105.31 ? 778 ASN A C   1 
ATOM 1118 O O   . ASN A 1 197 ? 112.190 130.433 118.446 1.00 105.31 ? 778 ASN A O   1 
ATOM 1119 C CB  . ASN A 1 197 ? 109.768 131.830 120.167 1.00 105.31 ? 778 ASN A CB  1 
ATOM 1120 C CG  . ASN A 1 197 ? 110.563 133.101 119.819 1.00 105.31 ? 778 ASN A CG  1 
ATOM 1121 O OD1 . ASN A 1 197 ? 111.719 133.071 119.406 1.00 105.31 ? 778 ASN A OD1 1 
ATOM 1122 N ND2 . ASN A 1 197 ? 109.909 134.242 120.001 1.00 105.31 ? 778 ASN A ND2 1 
ATOM 1123 N N   . MET A 1 198 ? 111.415 128.985 119.995 1.00 100.67 ? 779 MET A N   1 
ATOM 1124 C CA  . MET A 1 198 ? 112.706 128.317 120.174 1.00 100.67 ? 779 MET A CA  1 
ATOM 1125 C C   . MET A 1 198 ? 113.148 127.567 118.915 1.00 100.67 ? 779 MET A C   1 
ATOM 1126 O O   . MET A 1 198 ? 114.341 127.542 118.574 1.00 100.67 ? 779 MET A O   1 
ATOM 1127 C CB  . MET A 1 198 ? 112.615 127.365 121.370 1.00 100.67 ? 779 MET A CB  1 
ATOM 1128 C CG  . MET A 1 198 ? 113.889 126.617 121.711 1.00 100.67 ? 779 MET A CG  1 
ATOM 1129 S SD  . MET A 1 198 ? 114.042 126.383 123.489 1.00 100.67 ? 779 MET A SD  1 
ATOM 1130 C CE  . MET A 1 198 ? 112.902 125.028 123.753 1.00 100.67 ? 779 MET A CE  1 
ATOM 1131 N N   . THR A 1 199 ? 112.193 126.967 118.195 1.00 104.35 ? 780 THR A N   1 
ATOM 1132 C CA  . THR A 1 199 ? 112.567 126.154 117.042 1.00 104.35 ? 780 THR A CA  1 
ATOM 1133 C C   . THR A 1 199 ? 112.943 127.017 115.840 1.00 104.35 ? 780 THR A C   1 
ATOM 1134 O O   . THR A 1 199 ? 113.718 126.576 114.986 1.00 104.35 ? 780 THR A O   1 
ATOM 1135 C CB  . THR A 1 199 ? 111.456 125.154 116.691 1.00 104.35 ? 780 THR A CB  1 
ATOM 1136 O OG1 . THR A 1 199 ? 111.909 124.287 115.642 1.00 104.35 ? 780 THR A OG1 1 
ATOM 1137 C CG2 . THR A 1 199 ? 110.176 125.838 116.250 1.00 104.35 ? 780 THR A CG2 1 
ATOM 1138 N N   . LYS A 1 200 ? 112.461 128.269 115.783 1.00 105.98 ? 781 LYS A N   1 
ATOM 1139 C CA  . LYS A 1 200 ? 112.950 129.193 114.757 1.00 105.98 ? 781 LYS A CA  1 
ATOM 1140 C C   . LYS A 1 200 ? 114.391 129.594 115.025 1.00 105.98 ? 781 LYS A C   1 
ATOM 1141 O O   . LYS A 1 200 ? 115.183 129.745 114.088 1.00 105.98 ? 781 LYS A O   1 
ATOM 1142 C CB  . LYS A 1 200 ? 112.086 130.457 114.650 1.00 105.98 ? 781 LYS A CB  1 
ATOM 1143 C CG  . LYS A 1 200 ? 110.638 130.369 115.074 1.00 105.98 ? 781 LYS A CG  1 
ATOM 1144 C CD  . LYS A 1 200 ? 109.807 129.494 114.141 1.00 105.98 ? 781 LYS A CD  1 
ATOM 1145 C CE  . LYS A 1 200 ? 108.370 129.975 114.069 1.00 105.98 ? 781 LYS A CE  1 
ATOM 1146 N NZ  . LYS A 1 200 ? 107.605 129.231 113.034 1.00 105.98 ? 781 LYS A NZ  1 
ATOM 1147 N N   . CYS A 1 201 ? 114.744 129.768 116.305 1.00 106.78 ? 782 CYS A N   1 
ATOM 1148 C CA  . CYS A 1 201 ? 116.121 130.072 116.683 1.00 106.78 ? 782 CYS A CA  1 
ATOM 1149 C C   . CYS A 1 201 ? 117.052 128.915 116.351 1.00 106.78 ? 782 CYS A C   1 
ATOM 1150 O O   . CYS A 1 201 ? 118.139 129.117 115.798 1.00 106.78 ? 782 CYS A O   1 
ATOM 1151 C CB  . CYS A 1 201 ? 116.194 130.396 118.174 1.00 106.78 ? 782 CYS A CB  1 
ATOM 1152 S SG  . CYS A 1 201 ? 115.200 131.802 118.676 1.00 106.78 ? 782 CYS A SG  1 
ATOM 1153 N N   . LEU A 1 202 ? 116.615 127.685 116.641 1.00 106.66 ? 783 LEU A N   1 
ATOM 1154 C CA  . LEU A 1 202 ? 117.459 126.527 116.356 1.00 106.66 ? 783 LEU A CA  1 
ATOM 1155 C C   . LEU A 1 202 ? 117.535 126.234 114.858 1.00 106.66 ? 783 LEU A C   1 
ATOM 1156 O O   . LEU A 1 202 ? 118.583 125.806 114.363 1.00 106.66 ? 783 LEU A O   1 
ATOM 1157 C CB  . LEU A 1 202 ? 116.970 125.306 117.132 1.00 106.66 ? 783 LEU A CB  1 
ATOM 1158 C CG  . LEU A 1 202 ? 117.406 125.306 118.600 1.00 106.66 ? 783 LEU A CG  1 
ATOM 1159 C CD1 . LEU A 1 202 ? 116.866 124.094 119.338 1.00 106.66 ? 783 LEU A CD1 1 
ATOM 1160 C CD2 . LEU A 1 202 ? 118.925 125.367 118.711 1.00 106.66 ? 783 LEU A CD2 1 
ATOM 1161 N N   . GLN A 1 203 ? 116.456 126.505 114.113 1.00 107.98 ? 784 GLN A N   1 
ATOM 1162 C CA  . GLN A 1 203 ? 116.479 126.331 112.662 1.00 107.98 ? 784 GLN A CA  1 
ATOM 1163 C C   . GLN A 1 203 ? 117.363 127.375 111.987 1.00 107.98 ? 784 GLN A C   1 
ATOM 1164 O O   . GLN A 1 203 ? 118.126 127.053 111.063 1.00 107.98 ? 784 GLN A O   1 
ATOM 1165 C CB  . GLN A 1 203 ? 115.050 126.395 112.117 1.00 107.98 ? 784 GLN A CB  1 
ATOM 1166 C CG  . GLN A 1 203 ? 114.930 126.347 110.603 1.00 107.98 ? 784 GLN A CG  1 
ATOM 1167 C CD  . GLN A 1 203 ? 113.488 126.338 110.136 1.00 107.98 ? 784 GLN A CD  1 
ATOM 1168 O OE1 . GLN A 1 203 ? 112.667 127.126 110.603 1.00 107.98 ? 784 GLN A OE1 1 
ATOM 1169 N NE2 . GLN A 1 203 ? 113.173 125.441 109.208 1.00 107.98 ? 784 GLN A NE2 1 
ATOM 1170 N N   . SER A 1 204 ? 117.285 128.630 112.449 1.00 105.15 ? 785 SER A N   1 
ATOM 1171 C CA  . SER A 1 204 ? 118.139 129.689 111.922 1.00 105.15 ? 785 SER A CA  1 
ATOM 1172 C C   . SER A 1 204 ? 119.599 129.453 112.282 1.00 105.15 ? 785 SER A C   1 
ATOM 1173 O O   . SER A 1 204 ? 120.489 129.742 111.479 1.00 105.15 ? 785 SER A O   1 
ATOM 1174 C CB  . SER A 1 204 ? 117.671 131.046 112.445 1.00 105.15 ? 785 SER A CB  1 
ATOM 1175 O OG  . SER A 1 204 ? 118.138 131.269 113.763 1.00 105.15 ? 785 SER A OG  1 
ATOM 1176 N N   . LEU A 1 205 ? 119.861 128.888 113.463 1.00 104.70 ? 786 LEU A N   1 
ATOM 1177 C CA  . LEU A 1 205 ? 121.231 128.566 113.848 1.00 104.70 ? 786 LEU A CA  1 
ATOM 1178 C C   . LEU A 1 205 ? 121.771 127.384 113.044 1.00 104.70 ? 786 LEU A C   1 
ATOM 1179 O O   . LEU A 1 205 ? 122.953 127.366 112.670 1.00 104.70 ? 786 LEU A O   1 
ATOM 1180 C CB  . LEU A 1 205 ? 121.276 128.277 115.347 1.00 104.70 ? 786 LEU A CB  1 
ATOM 1181 C CG  . LEU A 1 205 ? 122.634 127.988 115.968 1.00 104.70 ? 786 LEU A CG  1 
ATOM 1182 C CD1 . LEU A 1 205 ? 123.512 129.215 115.814 1.00 104.70 ? 786 LEU A CD1 1 
ATOM 1183 C CD2 . LEU A 1 205 ? 122.474 127.618 117.425 1.00 104.70 ? 786 LEU A CD2 1 
ATOM 1184 N N   . LYS A 1 206 ? 120.905 126.398 112.758 1.00 104.41 ? 787 LYS A N   1 
ATOM 1185 C CA  . LYS A 1 206 ? 121.259 125.259 111.911 1.00 104.41 ? 787 LYS A CA  1 
ATOM 1186 C C   . LYS A 1 206 ? 121.609 125.693 110.494 1.00 104.41 ? 787 LYS A C   1 
ATOM 1187 O O   . LYS A 1 206 ? 122.610 125.239 109.927 1.00 104.41 ? 787 LYS A O   1 
ATOM 1188 C CB  . LYS A 1 206 ? 120.092 124.274 111.872 1.00 104.41 ? 787 LYS A CB  1 
ATOM 1189 C CG  . LYS A 1 206 ? 120.332 123.018 111.053 1.00 104.41 ? 787 LYS A CG  1 
ATOM 1190 C CD  . LYS A 1 206 ? 119.158 122.068 111.191 1.00 104.41 ? 787 LYS A CD  1 
ATOM 1191 C CE  . LYS A 1 206 ? 117.949 122.578 110.424 1.00 104.41 ? 787 LYS A CE  1 
ATOM 1192 N NZ  . LYS A 1 206 ? 116.817 121.612 110.443 1.00 104.41 ? 787 LYS A NZ  1 
ATOM 1193 N N   . GLU A 1 207 ? 120.800 126.574 109.910 1.00 111.11 ? 788 GLU A N   1 
ATOM 1194 C CA  . GLU A 1 207 ? 121.084 127.095 108.580 1.00 111.11 ? 788 GLU A CA  1 
ATOM 1195 C C   . GLU A 1 207 ? 122.233 128.100 108.596 1.00 111.11 ? 788 GLU A C   1 
ATOM 1196 O O   . GLU A 1 207 ? 122.913 128.264 107.576 1.00 111.11 ? 788 GLU A O   1 
ATOM 1197 C CB  . GLU A 1 207 ? 119.790 127.699 107.991 1.00 111.11 ? 788 GLU A CB  1 
ATOM 1198 C CG  . GLU A 1 207 ? 119.787 128.097 106.502 1.00 111.11 ? 788 GLU A CG  1 
ATOM 1199 C CD  . GLU A 1 207 ? 120.359 129.474 106.220 1.00 111.11 ? 788 GLU A CD  1 
ATOM 1200 O OE1 . GLU A 1 207 ? 120.268 130.347 107.108 1.00 111.11 ? 788 GLU A OE1 1 
ATOM 1201 O OE2 . GLU A 1 207 ? 120.904 129.680 105.115 1.00 111.11 ? 788 GLU A OE2 1 
ATOM 1202 N N   . MET A 1 208 ? 122.496 128.730 109.743 1.00 109.70 ? 789 MET A N   1 
ATOM 1203 C CA  . MET A 1 208 ? 123.586 129.690 109.855 1.00 109.70 ? 789 MET A CA  1 
ATOM 1204 C C   . MET A 1 208 ? 124.940 128.993 109.923 1.00 109.70 ? 789 MET A C   1 
ATOM 1205 O O   . MET A 1 208 ? 125.914 129.469 109.327 1.00 109.70 ? 789 MET A O   1 
ATOM 1206 C CB  . MET A 1 208 ? 123.351 130.563 111.090 1.00 109.70 ? 789 MET A CB  1 
ATOM 1207 C CG  . MET A 1 208 ? 124.491 131.484 111.485 1.00 109.70 ? 789 MET A CG  1 
ATOM 1208 S SD  . MET A 1 208 ? 125.023 132.580 110.160 1.00 109.70 ? 789 MET A SD  1 
ATOM 1209 C CE  . MET A 1 208 ? 125.800 133.879 111.114 1.00 109.70 ? 789 MET A CE  1 
ATOM 1210 N N   . TYR A 1 209 ? 125.013 127.847 110.615 1.00 109.21 ? 790 TYR A N   1 
ATOM 1211 C CA  . TYR A 1 209 ? 126.291 127.147 110.770 1.00 109.21 ? 790 TYR A CA  1 
ATOM 1212 C C   . TYR A 1 209 ? 126.768 126.518 109.463 1.00 109.21 ? 790 TYR A C   1 
ATOM 1213 O O   . TYR A 1 209 ? 127.961 126.229 109.311 1.00 109.21 ? 790 TYR A O   1 
ATOM 1214 C CB  . TYR A 1 209 ? 126.192 126.069 111.848 1.00 109.21 ? 790 TYR A CB  1 
ATOM 1215 C CG  . TYR A 1 209 ? 126.507 126.543 113.246 1.00 109.21 ? 790 TYR A CG  1 
ATOM 1216 C CD1 . TYR A 1 209 ? 125.720 126.155 114.326 1.00 109.21 ? 790 TYR A CD1 1 
ATOM 1217 C CD2 . TYR A 1 209 ? 127.577 127.402 113.482 1.00 109.21 ? 790 TYR A CD2 1 
ATOM 1218 C CE1 . TYR A 1 209 ? 126.010 126.581 115.610 1.00 109.21 ? 790 TYR A CE1 1 
ATOM 1219 C CE2 . TYR A 1 209 ? 127.871 127.841 114.763 1.00 109.21 ? 790 TYR A CE2 1 
ATOM 1220 C CZ  . TYR A 1 209 ? 127.080 127.429 115.821 1.00 109.21 ? 790 TYR A CZ  1 
ATOM 1221 O OH  . TYR A 1 209 ? 127.363 127.862 117.095 1.00 109.21 ? 790 TYR A OH  1 
ATOM 1222 N N   . GLN A 1 210 ? 125.855 126.289 108.517 1.00 118.73 ? 791 GLN A N   1 
ATOM 1223 C CA  . GLN A 1 210 ? 126.231 125.725 107.224 1.00 118.73 ? 791 GLN A CA  1 
ATOM 1224 C C   . GLN A 1 210 ? 126.992 126.746 106.380 1.00 118.73 ? 791 GLN A C   1 
ATOM 1225 O O   . GLN A 1 210 ? 127.851 126.384 105.567 1.00 118.73 ? 791 GLN A O   1 
ATOM 1226 C CB  . GLN A 1 210 ? 124.971 125.233 106.503 1.00 118.73 ? 791 GLN A CB  1 
ATOM 1227 C CG  . GLN A 1 210 ? 125.205 124.484 105.199 1.00 118.73 ? 791 GLN A CG  1 
ATOM 1228 C CD  . GLN A 1 210 ? 125.998 123.209 105.398 1.00 118.73 ? 791 GLN A CD  1 
ATOM 1229 O OE1 . GLN A 1 210 ? 127.183 123.144 105.070 1.00 118.73 ? 791 GLN A OE1 1 
ATOM 1230 N NE2 . GLN A 1 210 ? 125.349 122.187 105.943 1.00 118.73 ? 791 GLN A NE2 1 
ATOM 1231 N N   . ASP A 1 211 ? 126.702 128.035 106.584 1.00 128.10 ? 792 ASP A N   1 
ATOM 1232 C CA  . ASP A 1 211 ? 127.260 129.080 105.728 1.00 128.10 ? 792 ASP A CA  1 
ATOM 1233 C C   . ASP A 1 211 ? 128.735 129.328 106.033 1.00 128.10 ? 792 ASP A C   1 
ATOM 1234 O O   . ASP A 1 211 ? 129.551 129.477 105.115 1.00 128.10 ? 792 ASP A O   1 
ATOM 1235 C CB  . ASP A 1 211 ? 126.444 130.365 105.889 1.00 128.10 ? 792 ASP A CB  1 
ATOM 1236 C CG  . ASP A 1 211 ? 126.511 131.270 104.664 1.00 128.10 ? 792 ASP A CG  1 
ATOM 1237 O OD1 . ASP A 1 211 ? 127.621 131.551 104.163 1.00 128.10 ? 792 ASP A OD1 1 
ATOM 1238 O OD2 . ASP A 1 211 ? 125.437 131.704 104.196 1.00 128.10 ? 792 ASP A OD2 1 
ATOM 1239 N N   . LEU A 1 212 ? 129.100 129.386 107.318 1.00 127.59 ? 793 LEU A N   1 
ATOM 1240 C CA  . LEU A 1 212 ? 130.502 129.608 107.667 1.00 127.59 ? 793 LEU A CA  1 
ATOM 1241 C C   . LEU A 1 212 ? 131.334 128.348 107.468 1.00 127.59 ? 793 LEU A C   1 
ATOM 1242 O O   . LEU A 1 212 ? 132.556 128.426 107.292 1.00 127.59 ? 793 LEU A O   1 
ATOM 1243 C CB  . LEU A 1 212 ? 130.638 130.113 109.106 1.00 127.59 ? 793 LEU A CB  1 
ATOM 1244 C CG  . LEU A 1 212 ? 129.983 131.431 109.534 1.00 127.59 ? 793 LEU A CG  1 
ATOM 1245 C CD1 . LEU A 1 212 ? 128.608 131.229 110.146 1.00 127.59 ? 793 LEU A CD1 1 
ATOM 1246 C CD2 . LEU A 1 212 ? 130.895 132.179 110.496 1.00 127.59 ? 793 LEU A CD2 1 
ATOM 1247 N N   . ARG A 1 213 ? 130.694 127.177 107.512 1.00 121.50 ? 794 ARG A N   1 
ATOM 1248 C CA  . ARG A 1 213 ? 131.403 125.929 107.247 1.00 121.50 ? 794 ARG A CA  1 
ATOM 1249 C C   . ARG A 1 213 ? 131.780 125.818 105.773 1.00 121.50 ? 794 ARG A C   1 
ATOM 1250 O O   . ARG A 1 213 ? 132.895 125.395 105.439 1.00 121.50 ? 794 ARG A O   1 
ATOM 1251 C CB  . ARG A 1 213 ? 130.543 124.745 107.702 1.00 121.50 ? 794 ARG A CB  1 
ATOM 1252 C CG  . ARG A 1 213 ? 130.795 123.422 106.994 1.00 121.50 ? 794 ARG A CG  1 
ATOM 1253 C CD  . ARG A 1 213 ? 130.507 122.253 107.918 1.00 121.50 ? 794 ARG A CD  1 
ATOM 1254 N NE  . ARG A 1 213 ? 131.343 122.293 109.112 1.00 121.50 ? 794 ARG A NE  1 
ATOM 1255 C CZ  . ARG A 1 213 ? 130.928 121.971 110.329 1.00 121.50 ? 794 ARG A CZ  1 
ATOM 1256 N NH1 . ARG A 1 213 ? 129.683 121.585 110.555 1.00 121.50 ? 794 ARG A NH1 1 
ATOM 1257 N NH2 . ARG A 1 213 ? 131.783 122.040 111.345 1.00 121.50 ? 794 ARG A NH2 1 
ATOM 1258 N N   . ASN A 1 214 ? 130.877 126.236 104.881 1.00 132.40 ? 795 ASN A N   1 
ATOM 1259 C CA  . ASN A 1 214 ? 131.185 126.255 103.454 1.00 132.40 ? 795 ASN A CA  1 
ATOM 1260 C C   . ASN A 1 214 ? 132.181 127.361 103.119 1.00 132.40 ? 795 ASN A C   1 
ATOM 1261 O O   . ASN A 1 214 ? 132.940 127.251 102.148 1.00 132.40 ? 795 ASN A O   1 
ATOM 1262 C CB  . ASN A 1 214 ? 129.896 126.420 102.647 1.00 132.40 ? 795 ASN A CB  1 
ATOM 1263 C CG  . ASN A 1 214 ? 130.118 126.287 101.154 1.00 132.40 ? 795 ASN A CG  1 
ATOM 1264 O OD1 . ASN A 1 214 ? 130.944 125.493 100.706 1.00 132.40 ? 795 ASN A OD1 1 
ATOM 1265 N ND2 . ASN A 1 214 ? 129.379 127.067 100.374 1.00 132.40 ? 795 ASN A ND2 1 
ATOM 1266 N N   . LYS A 1 215 ? 132.182 128.441 103.907 1.00 135.19 ? 796 LYS A N   1 
ATOM 1267 C CA  . LYS A 1 215 ? 133.186 129.489 103.764 1.00 135.19 ? 796 LYS A CA  1 
ATOM 1268 C C   . LYS A 1 215 ? 134.580 128.994 104.137 1.00 135.19 ? 796 LYS A C   1 
ATOM 1269 O O   . LYS A 1 215 ? 135.548 129.305 103.434 1.00 135.19 ? 796 LYS A O   1 
ATOM 1270 C CB  . LYS A 1 215 ? 132.790 130.697 104.623 1.00 135.19 ? 796 LYS A CB  1 
ATOM 1271 C CG  . LYS A 1 215 ? 133.834 131.805 104.747 1.00 135.19 ? 796 LYS A CG  1 
ATOM 1272 C CD  . LYS A 1 215 ? 134.175 132.424 103.397 1.00 135.19 ? 796 LYS A CD  1 
ATOM 1273 C CE  . LYS A 1 215 ? 133.036 133.286 102.881 1.00 135.19 ? 796 LYS A CE  1 
ATOM 1274 N NZ  . LYS A 1 215 ? 133.225 133.656 101.451 1.00 135.19 ? 796 LYS A NZ  1 
ATOM 1275 N N   . GLY A 1 216 ? 134.698 128.209 105.203 1.00 134.19 ? 797 GLY A N   1 
ATOM 1276 C CA  . GLY A 1 216 ? 135.978 127.652 105.583 1.00 134.19 ? 797 GLY A CA  1 
ATOM 1277 C C   . GLY A 1 216 ? 136.467 128.037 106.958 1.00 134.19 ? 797 GLY A C   1 
ATOM 1278 O O   . GLY A 1 216 ? 137.663 127.902 107.238 1.00 134.19 ? 797 GLY A O   1 
ATOM 1279 N N   . VAL A 1 217 ? 135.583 128.515 107.829 1.00 132.66 ? 798 VAL A N   1 
ATOM 1280 C CA  . VAL A 1 217 ? 135.935 128.871 109.198 1.00 132.66 ? 798 VAL A CA  1 
ATOM 1281 C C   . VAL A 1 217 ? 135.080 128.013 110.130 1.00 132.66 ? 798 VAL A C   1 
ATOM 1282 O O   . VAL A 1 217 ? 133.928 127.690 109.811 1.00 132.66 ? 798 VAL A O   1 
ATOM 1283 C CB  . VAL A 1 217 ? 135.780 130.389 109.452 1.00 132.66 ? 798 VAL A CB  1 
ATOM 1284 C CG1 . VAL A 1 217 ? 134.329 130.877 109.342 1.00 132.66 ? 798 VAL A CG1 1 
ATOM 1285 C CG2 . VAL A 1 217 ? 136.413 130.810 110.782 1.00 132.66 ? 798 VAL A CG2 1 
ATOM 1286 N N   . PHE A 1 218 ? 135.680 127.552 111.223 1.00 132.33 ? 799 PHE A N   1 
ATOM 1287 C CA  . PHE A 1 218 ? 134.988 126.705 112.180 1.00 132.33 ? 799 PHE A CA  1 
ATOM 1288 C C   . PHE A 1 218 ? 134.620 127.524 113.415 1.00 132.33 ? 799 PHE A C   1 
ATOM 1289 O O   . PHE A 1 218 ? 134.934 128.712 113.519 1.00 132.33 ? 799 PHE A O   1 
ATOM 1290 C CB  . PHE A 1 218 ? 135.852 125.495 112.531 1.00 132.33 ? 799 PHE A CB  1 
ATOM 1291 C CG  . PHE A 1 218 ? 135.875 124.438 111.466 1.00 132.33 ? 799 PHE A CG  1 
ATOM 1292 C CD1 . PHE A 1 218 ? 137.081 123.915 111.016 1.00 132.33 ? 799 PHE A CD1 1 
ATOM 1293 C CD2 . PHE A 1 218 ? 134.691 123.966 110.913 1.00 132.33 ? 799 PHE A CD2 1 
ATOM 1294 C CE1 . PHE A 1 218 ? 137.107 122.939 110.032 1.00 132.33 ? 799 PHE A CE1 1 
ATOM 1295 C CE2 . PHE A 1 218 ? 134.708 122.991 109.928 1.00 132.33 ? 799 PHE A CE2 1 
ATOM 1296 C CZ  . PHE A 1 218 ? 135.918 122.477 109.488 1.00 132.33 ? 799 PHE A CZ  1 
ATOM 1297 N N   . CYS A 1 219 ? 133.944 126.890 114.370 1.00 131.95 ? 800 CYS A N   1 
ATOM 1298 C CA  . CYS A 1 219 ? 133.589 127.546 115.618 1.00 131.95 ? 800 CYS A CA  1 
ATOM 1299 C C   . CYS A 1 219 ? 133.717 126.545 116.756 1.00 131.95 ? 800 CYS A C   1 
ATOM 1300 O O   . CYS A 1 219 ? 133.504 125.343 116.572 1.00 131.95 ? 800 CYS A O   1 
ATOM 1301 C CB  . CYS A 1 219 ? 132.169 128.121 115.569 1.00 131.95 ? 800 CYS A CB  1 
ATOM 1302 S SG  . CYS A 1 219 ? 131.558 128.721 117.160 1.00 131.95 ? 800 CYS A SG  1 
ATOM 1303 N N   . ALA A 1 220 ? 134.071 127.055 117.937 1.00 129.69 ? 801 ALA A N   1 
ATOM 1304 C CA  . ALA A 1 220 ? 134.195 126.190 119.105 1.00 129.69 ? 801 ALA A CA  1 
ATOM 1305 C C   . ALA A 1 220 ? 132.827 125.798 119.647 1.00 129.69 ? 801 ALA A C   1 
ATOM 1306 O O   . ALA A 1 220 ? 132.676 124.738 120.266 1.00 129.69 ? 801 ALA A O   1 
ATOM 1307 C CB  . ALA A 1 220 ? 135.026 126.881 120.186 1.00 129.69 ? 801 ALA A CB  1 
ATOM 1308 N N   . SER A 1 221 ? 131.816 126.639 119.421 1.00 119.52 ? 802 SER A N   1 
ATOM 1309 C CA  . SER A 1 221 ? 130.465 126.395 119.910 1.00 119.52 ? 802 SER A CA  1 
ATOM 1310 C C   . SER A 1 221 ? 129.542 125.837 118.834 1.00 119.52 ? 802 SER A C   1 
ATOM 1311 O O   . SER A 1 221 ? 128.326 126.063 118.888 1.00 119.52 ? 802 SER A O   1 
ATOM 1312 C CB  . SER A 1 221 ? 129.882 127.679 120.499 1.00 119.52 ? 802 SER A CB  1 
ATOM 1313 O OG  . SER A 1 221 ? 129.701 128.661 119.494 1.00 119.52 ? 802 SER A OG  1 
ATOM 1314 N N   . GLU A 1 222 ? 130.087 125.111 117.857 1.00 114.69 ? 803 GLU A N   1 
ATOM 1315 C CA  . GLU A 1 222 ? 129.253 124.567 116.790 1.00 114.69 ? 803 GLU A CA  1 
ATOM 1316 C C   . GLU A 1 222 ? 128.592 123.267 117.229 1.00 114.69 ? 803 GLU A C   1 
ATOM 1317 O O   . GLU A 1 222 ? 127.385 123.077 117.043 1.00 114.69 ? 803 GLU A O   1 
ATOM 1318 C CB  . GLU A 1 222 ? 130.097 124.362 115.526 1.00 114.69 ? 803 GLU A CB  1 
ATOM 1319 C CG  . GLU A 1 222 ? 129.318 124.328 114.204 1.00 114.69 ? 803 GLU A CG  1 
ATOM 1320 C CD  . GLU A 1 222 ? 128.784 122.960 113.804 1.00 114.69 ? 803 GLU A CD  1 
ATOM 1321 O OE1 . GLU A 1 222 ? 128.112 122.881 112.753 1.00 114.69 ? 803 GLU A OE1 1 
ATOM 1322 O OE2 . GLU A 1 222 ? 129.069 121.958 114.488 1.00 114.69 ? 803 GLU A OE2 1 
ATOM 1323 N N   . ALA A 1 223 ? 129.372 122.358 117.816 1.00 106.84 ? 804 ALA A N   1 
ATOM 1324 C CA  . ALA A 1 223 ? 128.875 121.032 118.158 1.00 106.84 ? 804 ALA A CA  1 
ATOM 1325 C C   . ALA A 1 223 ? 128.028 121.012 119.424 1.00 106.84 ? 804 ALA A C   1 
ATOM 1326 O O   . ALA A 1 223 ? 127.434 119.972 119.728 1.00 106.84 ? 804 ALA A O   1 
ATOM 1327 C CB  . ALA A 1 223 ? 130.046 120.060 118.312 1.00 106.84 ? 804 ALA A CB  1 
ATOM 1328 N N   . GLU A 1 224 ? 127.964 122.118 120.168 1.00 112.78 ? 805 GLU A N   1 
ATOM 1329 C CA  . GLU A 1 224 ? 127.188 122.134 121.403 1.00 112.78 ? 805 GLU A CA  1 
ATOM 1330 C C   . GLU A 1 224 ? 125.690 122.176 121.123 1.00 112.78 ? 805 GLU A C   1 
ATOM 1331 O O   . GLU A 1 224 ? 124.945 121.292 121.560 1.00 112.78 ? 805 GLU A O   1 
ATOM 1332 C CB  . GLU A 1 224 ? 127.619 123.315 122.276 1.00 112.78 ? 805 GLU A CB  1 
ATOM 1333 C CG  . GLU A 1 224 ? 128.786 123.013 123.220 1.00 112.78 ? 805 GLU A CG  1 
ATOM 1334 C CD  . GLU A 1 224 ? 130.162 123.147 122.580 1.00 112.78 ? 805 GLU A CD  1 
ATOM 1335 O OE1 . GLU A 1 224 ? 130.252 123.395 121.360 1.00 112.78 ? 805 GLU A OE1 1 
ATOM 1336 O OE2 . GLU A 1 224 ? 131.165 122.998 123.310 1.00 112.78 ? 805 GLU A OE2 1 
ATOM 1337 N N   . PHE A 1 225 ? 125.230 123.181 120.376 1.00 104.40 ? 806 PHE A N   1 
ATOM 1338 C CA  . PHE A 1 225 ? 123.798 123.363 120.167 1.00 104.40 ? 806 PHE A CA  1 
ATOM 1339 C C   . PHE A 1 225 ? 123.209 122.457 119.096 1.00 104.40 ? 806 PHE A C   1 
ATOM 1340 O O   . PHE A 1 225 ? 121.982 122.405 118.967 1.00 104.40 ? 806 PHE A O   1 
ATOM 1341 C CB  . PHE A 1 225 ? 123.470 124.825 119.834 1.00 104.40 ? 806 PHE A CB  1 
ATOM 1342 C CG  . PHE A 1 225 ? 123.635 125.765 120.996 1.00 104.40 ? 806 PHE A CG  1 
ATOM 1343 C CD1 . PHE A 1 225 ? 123.599 125.291 122.298 1.00 104.40 ? 806 PHE A CD1 1 
ATOM 1344 C CD2 . PHE A 1 225 ? 123.760 127.124 120.795 1.00 104.40 ? 806 PHE A CD2 1 
ATOM 1345 C CE1 . PHE A 1 225 ? 123.728 126.139 123.373 1.00 104.40 ? 806 PHE A CE1 1 
ATOM 1346 C CE2 . PHE A 1 225 ? 123.878 127.974 121.872 1.00 104.40 ? 806 PHE A CE2 1 
ATOM 1347 C CZ  . PHE A 1 225 ? 123.869 127.485 123.154 1.00 104.40 ? 806 PHE A CZ  1 
ATOM 1348 N N   . GLN A 1 226 ? 124.033 121.714 118.354 1.00 100.74 ? 807 GLN A N   1 
ATOM 1349 C CA  . GLN A 1 226 ? 123.484 120.669 117.497 1.00 100.74 ? 807 GLN A CA  1 
ATOM 1350 C C   . GLN A 1 226 ? 122.937 119.518 118.332 1.00 100.74 ? 807 GLN A C   1 
ATOM 1351 O O   . GLN A 1 226 ? 121.956 118.866 117.943 1.00 100.74 ? 807 GLN A O   1 
ATOM 1352 C CB  . GLN A 1 226 ? 124.549 120.184 116.511 1.00 100.74 ? 807 GLN A CB  1 
ATOM 1353 C CG  . GLN A 1 226 ? 124.883 121.144 115.345 1.00 100.74 ? 807 GLN A CG  1 
ATOM 1354 C CD  . GLN A 1 226 ? 123.838 121.236 114.216 1.00 100.74 ? 807 GLN A CD  1 
ATOM 1355 O OE1 . GLN A 1 226 ? 122.624 121.238 114.431 1.00 100.74 ? 807 GLN A OE1 1 
ATOM 1356 N NE2 . GLN A 1 226 ? 124.336 121.329 112.991 1.00 100.74 ? 807 GLN A NE2 1 
ATOM 1357 N N   . GLY A 1 227 ? 123.539 119.287 119.505 1.00 98.14  ? 808 GLY A N   1 
ATOM 1358 C CA  . GLY A 1 227 ? 122.960 118.365 120.468 1.00 98.14  ? 808 GLY A CA  1 
ATOM 1359 C C   . GLY A 1 227 ? 121.600 118.815 120.969 1.00 98.14  ? 808 GLY A C   1 
ATOM 1360 O O   . GLY A 1 227 ? 120.669 118.019 121.035 1.00 98.14  ? 808 GLY A O   1 
ATOM 1361 N N   . TYR A 1 228 ? 121.458 120.108 121.278 1.00 97.91  ? 809 TYR A N   1 
ATOM 1362 C CA  . TYR A 1 228 ? 120.165 120.689 121.649 1.00 97.91  ? 809 TYR A CA  1 
ATOM 1363 C C   . TYR A 1 228 ? 119.156 120.663 120.505 1.00 97.91  ? 809 TYR A C   1 
ATOM 1364 O O   . TYR A 1 228 ? 117.948 120.580 120.760 1.00 97.91  ? 809 TYR A O   1 
ATOM 1365 C CB  . TYR A 1 228 ? 120.366 122.129 122.131 1.00 97.91  ? 809 TYR A CB  1 
ATOM 1366 C CG  . TYR A 1 228 ? 121.134 122.281 123.433 1.00 97.91  ? 809 TYR A CG  1 
ATOM 1367 C CD1 . TYR A 1 228 ? 120.464 122.381 124.648 1.00 97.91  ? 809 TYR A CD1 1 
ATOM 1368 C CD2 . TYR A 1 228 ? 122.524 122.256 123.454 1.00 97.91  ? 809 TYR A CD2 1 
ATOM 1369 C CE1 . TYR A 1 228 ? 121.163 122.521 125.838 1.00 97.91  ? 809 TYR A CE1 1 
ATOM 1370 C CE2 . TYR A 1 228 ? 123.230 122.387 124.630 1.00 97.91  ? 809 TYR A CE2 1 
ATOM 1371 C CZ  . TYR A 1 228 ? 122.550 122.512 125.818 1.00 97.91  ? 809 TYR A CZ  1 
ATOM 1372 O OH  . TYR A 1 228 ? 123.276 122.629 126.979 1.00 97.91  ? 809 TYR A OH  1 
ATOM 1373 N N   . ASN A 1 229 ? 119.635 120.744 119.260 1.00 98.84  ? 810 ASN A N   1 
ATOM 1374 C CA  . ASN A 1 229 ? 118.776 120.605 118.088 1.00 98.84  ? 810 ASN A CA  1 
ATOM 1375 C C   . ASN A 1 229 ? 118.226 119.178 118.029 1.00 98.84  ? 810 ASN A C   1 
ATOM 1376 O O   . ASN A 1 229 ? 117.047 118.972 117.718 1.00 98.84  ? 810 ASN A O   1 
ATOM 1377 C CB  . ASN A 1 229 ? 119.610 120.992 116.845 1.00 98.84  ? 810 ASN A CB  1 
ATOM 1378 C CG  . ASN A 1 229 ? 118.908 120.806 115.464 1.00 98.84  ? 810 ASN A CG  1 
ATOM 1379 O OD1 . ASN A 1 229 ? 119.404 121.106 114.379 1.00 98.84  ? 810 ASN A OD1 1 
ATOM 1380 N ND2 . ASN A 1 229 ? 117.693 120.287 115.549 1.00 98.84  ? 810 ASN A ND2 1 
ATOM 1381 N N   . VAL A 1 230 ? 119.066 118.183 118.339 1.00 95.84  ? 811 VAL A N   1 
ATOM 1382 C CA  . VAL A 1 230 ? 118.584 116.799 118.372 1.00 95.84  ? 811 VAL A CA  1 
ATOM 1383 C C   . VAL A 1 230 ? 117.645 116.575 119.563 1.00 95.84  ? 811 VAL A C   1 
ATOM 1384 O O   . VAL A 1 230 ? 116.588 115.947 119.422 1.00 95.84  ? 811 VAL A O   1 
ATOM 1385 C CB  . VAL A 1 230 ? 119.770 115.813 118.374 1.00 95.84  ? 811 VAL A CB  1 
ATOM 1386 C CG1 . VAL A 1 230 ? 119.288 114.368 118.497 1.00 95.84  ? 811 VAL A CG1 1 
ATOM 1387 C CG2 . VAL A 1 230 ? 120.583 115.966 117.106 1.00 95.84  ? 811 VAL A CG2 1 
ATOM 1388 N N   . LEU A 1 231 ? 117.983 117.131 120.737 1.00 93.51  ? 812 LEU A N   1 
ATOM 1389 C CA  . LEU A 1 231 ? 117.115 117.005 121.914 1.00 93.51  ? 812 LEU A CA  1 
ATOM 1390 C C   . LEU A 1 231 ? 115.801 117.775 121.793 1.00 93.51  ? 812 LEU A C   1 
ATOM 1391 O O   . LEU A 1 231 ? 114.872 117.511 122.566 1.00 93.51  ? 812 LEU A O   1 
ATOM 1392 C CB  . LEU A 1 231 ? 117.820 117.423 123.213 1.00 93.51  ? 812 LEU A CB  1 
ATOM 1393 C CG  . LEU A 1 231 ? 118.726 116.537 124.078 1.00 93.51  ? 812 LEU A CG  1 
ATOM 1394 C CD1 . LEU A 1 231 ? 117.878 115.404 124.619 1.00 93.51  ? 812 LEU A CD1 1 
ATOM 1395 C CD2 . LEU A 1 231 ? 119.930 115.969 123.413 1.00 93.51  ? 812 LEU A CD2 1 
ATOM 1396 N N   . LEU A 1 232 ? 115.698 118.731 120.868 1.00 96.21  ? 813 LEU A N   1 
ATOM 1397 C CA  . LEU A 1 232 ? 114.424 119.414 120.657 1.00 96.21  ? 813 LEU A CA  1 
ATOM 1398 C C   . LEU A 1 232 ? 113.373 118.489 120.051 1.00 96.21  ? 813 LEU A C   1 
ATOM 1399 O O   . LEU A 1 232 ? 112.238 118.429 120.535 1.00 96.21  ? 813 LEU A O   1 
ATOM 1400 C CB  . LEU A 1 232 ? 114.607 120.642 119.762 1.00 96.21  ? 813 LEU A CB  1 
ATOM 1401 C CG  . LEU A 1 232 ? 113.324 121.451 119.545 1.00 96.21  ? 813 LEU A CG  1 
ATOM 1402 C CD1 . LEU A 1 232 ? 112.815 122.015 120.861 1.00 96.21  ? 813 LEU A CD1 1 
ATOM 1403 C CD2 . LEU A 1 232 ? 113.525 122.556 118.526 1.00 96.21  ? 813 LEU A CD2 1 
ATOM 1404 N N   . SER A 1 233 ? 113.746 117.744 119.014 1.00 93.13  ? 814 SER A N   1 
ATOM 1405 C CA  . SER A 1 233 ? 112.810 116.924 118.253 1.00 93.13  ? 814 SER A CA  1 
ATOM 1406 C C   . SER A 1 233 ? 113.175 115.452 118.410 1.00 93.13  ? 814 SER A C   1 
ATOM 1407 O O   . SER A 1 233 ? 113.984 114.922 117.641 1.00 93.13  ? 814 SER A O   1 
ATOM 1408 C CB  . SER A 1 233 ? 112.810 117.334 116.783 1.00 93.13  ? 814 SER A CB  1 
ATOM 1409 O OG  . SER A 1 233 ? 114.103 117.205 116.219 1.00 93.13  ? 814 SER A OG  1 
ATOM 1410 N N   . LEU A 1 234 ? 112.577 114.799 119.403 1.00 89.74  ? 815 LEU A N   1 
ATOM 1411 C CA  . LEU A 1 234 ? 112.653 113.352 119.557 1.00 89.74  ? 815 LEU A CA  1 
ATOM 1412 C C   . LEU A 1 234 ? 111.439 112.613 119.024 1.00 89.74  ? 815 LEU A C   1 
ATOM 1413 O O   . LEU A 1 234 ? 111.578 111.471 118.582 1.00 89.74  ? 815 LEU A O   1 
ATOM 1414 C CB  . LEU A 1 234 ? 112.838 112.965 121.032 1.00 89.74  ? 815 LEU A CB  1 
ATOM 1415 C CG  . LEU A 1 234 ? 114.240 112.725 121.586 1.00 89.74  ? 815 LEU A CG  1 
ATOM 1416 C CD1 . LEU A 1 234 ? 114.977 114.008 121.715 1.00 89.74  ? 815 LEU A CD1 1 
ATOM 1417 C CD2 . LEU A 1 234 ? 114.161 112.023 122.931 1.00 89.74  ? 815 LEU A CD2 1 
ATOM 1418 N N   . ASN A 1 235 ? 110.253 113.224 119.058 1.00 90.55  ? 816 ASN A N   1 
ATOM 1419 C CA  . ASN A 1 235 ? 109.059 112.552 118.561 1.00 90.55  ? 816 ASN A CA  1 
ATOM 1420 C C   . ASN A 1 235 ? 108.997 112.536 117.039 1.00 90.55  ? 816 ASN A C   1 
ATOM 1421 O O   . ASN A 1 235 ? 108.230 111.753 116.469 1.00 90.55  ? 816 ASN A O   1 
ATOM 1422 C CB  . ASN A 1 235 ? 107.810 113.220 119.135 1.00 90.55  ? 816 ASN A CB  1 
ATOM 1423 C CG  . ASN A 1 235 ? 107.378 112.608 120.452 1.00 90.55  ? 816 ASN A CG  1 
ATOM 1424 O OD1 . ASN A 1 235 ? 108.023 111.694 120.966 1.00 90.55  ? 816 ASN A OD1 1 
ATOM 1425 N ND2 . ASN A 1 235 ? 106.284 113.112 121.009 1.00 90.55  ? 816 ASN A ND2 1 
ATOM 1426 N N   . LYS A 1 236 ? 109.781 113.380 116.372 1.00 93.03  ? 817 LYS A N   1 
ATOM 1427 C CA  . LYS A 1 236 ? 109.870 113.390 114.914 1.00 93.03  ? 817 LYS A CA  1 
ATOM 1428 C C   . LYS A 1 236 ? 111.014 112.468 114.511 1.00 93.03  ? 817 LYS A C   1 
ATOM 1429 O O   . LYS A 1 236 ? 112.169 112.692 114.883 1.00 93.03  ? 817 LYS A O   1 
ATOM 1430 C CB  . LYS A 1 236 ? 110.079 114.810 114.402 1.00 93.03  ? 817 LYS A CB  1 
ATOM 1431 C CG  . LYS A 1 236 ? 110.139 114.930 112.891 1.00 93.03  ? 817 LYS A CG  1 
ATOM 1432 C CD  . LYS A 1 236 ? 110.230 116.385 112.464 1.00 93.03  ? 817 LYS A CD  1 
ATOM 1433 C CE  . LYS A 1 236 ? 111.608 116.958 112.755 1.00 93.03  ? 817 LYS A CE  1 
ATOM 1434 N NZ  . LYS A 1 236 ? 111.755 118.346 112.236 1.00 93.03  ? 817 LYS A NZ  1 
ATOM 1435 N N   . GLY A 1 237 ? 110.696 111.425 113.745 1.00 98.04  ? 818 GLY A N   1 
ATOM 1436 C CA  . GLY A 1 237 ? 111.686 110.424 113.385 1.00 98.04  ? 818 GLY A CA  1 
ATOM 1437 C C   . GLY A 1 237 ? 112.512 110.752 112.158 1.00 98.04  ? 818 GLY A C   1 
ATOM 1438 O O   . GLY A 1 237 ? 113.334 109.924 111.752 1.00 98.04  ? 818 GLY A O   1 
ATOM 1439 N N   . ASP A 1 238 ? 112.318 111.930 111.562 1.00 104.40 ? 819 ASP A N   1 
ATOM 1440 C CA  . ASP A 1 238 ? 113.065 112.281 110.358 1.00 104.40 ? 819 ASP A CA  1 
ATOM 1441 C C   . ASP A 1 238 ? 114.498 112.684 110.689 1.00 104.40 ? 819 ASP A C   1 
ATOM 1442 O O   . ASP A 1 238 ? 115.389 112.596 109.831 1.00 104.40 ? 819 ASP A O   1 
ATOM 1443 C CB  . ASP A 1 238 ? 112.350 113.409 109.614 1.00 104.40 ? 819 ASP A CB  1 
ATOM 1444 C CG  . ASP A 1 238 ? 111.033 112.965 109.007 1.00 104.40 ? 819 ASP A CG  1 
ATOM 1445 O OD1 . ASP A 1 238 ? 110.906 111.771 108.663 1.00 104.40 ? 819 ASP A OD1 1 
ATOM 1446 O OD2 . ASP A 1 238 ? 110.123 113.811 108.877 1.00 104.40 ? 819 ASP A OD2 1 
ATOM 1447 N N   . ILE A 1 239 ? 114.749 113.068 111.946 1.00 103.56 ? 820 ILE A N   1 
ATOM 1448 C CA  . ILE A 1 239 ? 115.981 113.721 112.387 1.00 103.56 ? 820 ILE A CA  1 
ATOM 1449 C C   . ILE A 1 239 ? 117.173 112.762 112.349 1.00 103.56 ? 820 ILE A C   1 
ATOM 1450 O O   . ILE A 1 239 ? 118.330 113.204 112.322 1.00 103.56 ? 820 ILE A O   1 
ATOM 1451 C CB  . ILE A 1 239 ? 115.778 114.341 113.791 1.00 103.56 ? 820 ILE A CB  1 
ATOM 1452 C CG1 . ILE A 1 239 ? 116.735 115.513 114.034 1.00 103.56 ? 820 ILE A CG1 1 
ATOM 1453 C CG2 . ILE A 1 239 ? 115.897 113.305 114.908 1.00 103.56 ? 820 ILE A CG2 1 
ATOM 1454 C CD1 . ILE A 1 239 ? 116.480 116.702 113.141 1.00 103.56 ? 820 ILE A CD1 1 
ATOM 1455 N N   . LEU A 1 240 ? 116.892 111.450 112.299 1.00 103.41 ? 821 LEU A N   1 
ATOM 1456 C CA  . LEU A 1 240 ? 117.938 110.445 112.133 1.00 103.41 ? 821 LEU A CA  1 
ATOM 1457 C C   . LEU A 1 240 ? 118.631 110.584 110.784 1.00 103.41 ? 821 LEU A C   1 
ATOM 1458 O O   . LEU A 1 240 ? 119.846 110.368 110.682 1.00 103.41 ? 821 LEU A O   1 
ATOM 1459 C CB  . LEU A 1 240 ? 117.348 109.043 112.285 1.00 103.41 ? 821 LEU A CB  1 
ATOM 1460 C CG  . LEU A 1 240 ? 117.072 108.536 113.702 1.00 103.41 ? 821 LEU A CG  1 
ATOM 1461 C CD1 . LEU A 1 240 ? 116.810 107.038 113.686 1.00 103.41 ? 821 LEU A CD1 1 
ATOM 1462 C CD2 . LEU A 1 240 ? 118.205 108.877 114.663 1.00 103.41 ? 821 LEU A CD2 1 
ATOM 1463 N N   . ARG A 1 241 ? 117.878 110.975 109.746 1.00 105.68 ? 822 ARG A N   1 
ATOM 1464 C CA  . ARG A 1 241 ? 118.489 111.314 108.462 1.00 105.68 ? 822 ARG A CA  1 
ATOM 1465 C C   . ARG A 1 241 ? 119.431 112.498 108.614 1.00 105.68 ? 822 ARG A C   1 
ATOM 1466 O O   . ARG A 1 241 ? 120.539 112.497 108.057 1.00 105.68 ? 822 ARG A O   1 
ATOM 1467 C CB  . ARG A 1 241 ? 117.404 111.621 107.434 1.00 105.68 ? 822 ARG A CB  1 
ATOM 1468 C CG  . ARG A 1 241 ? 116.862 110.382 106.776 1.00 105.68 ? 822 ARG A CG  1 
ATOM 1469 C CD  . ARG A 1 241 ? 116.303 110.631 105.390 1.00 105.68 ? 822 ARG A CD  1 
ATOM 1470 N NE  . ARG A 1 241 ? 117.352 110.773 104.389 1.00 105.68 ? 822 ARG A NE  1 
ATOM 1471 C CZ  . ARG A 1 241 ? 117.301 111.618 103.369 1.00 105.68 ? 822 ARG A CZ  1 
ATOM 1472 N NH1 . ARG A 1 241 ? 116.248 112.393 103.166 1.00 105.68 ? 822 ARG A NH1 1 
ATOM 1473 N NH2 . ARG A 1 241 ? 118.326 111.678 102.524 1.00 105.68 ? 822 ARG A NH2 1 
ATOM 1474 N N   . GLU A 1 242 ? 119.037 113.460 109.458 1.00 102.93 ? 823 GLU A N   1 
ATOM 1475 C CA  . GLU A 1 242 ? 119.880 114.594 109.805 1.00 102.93 ? 823 GLU A CA  1 
ATOM 1476 C C   . GLU A 1 242 ? 121.157 114.156 110.515 1.00 102.93 ? 823 GLU A C   1 
ATOM 1477 O O   . GLU A 1 242 ? 122.230 114.708 110.232 1.00 102.93 ? 823 GLU A O   1 
ATOM 1478 C CB  . GLU A 1 242 ? 119.072 115.576 110.661 1.00 102.93 ? 823 GLU A CB  1 
ATOM 1479 C CG  . GLU A 1 242 ? 119.874 116.650 111.385 1.00 102.93 ? 823 GLU A CG  1 
ATOM 1480 C CD  . GLU A 1 242 ? 120.052 117.920 110.573 1.00 102.93 ? 823 GLU A CD  1 
ATOM 1481 O OE1 . GLU A 1 242 ? 120.354 118.963 111.184 1.00 102.93 ? 823 GLU A OE1 1 
ATOM 1482 O OE2 . GLU A 1 242 ? 119.882 117.886 109.336 1.00 102.93 ? 823 GLU A OE2 1 
ATOM 1483 N N   . VAL A 1 243 ? 121.107 113.096 111.336 1.00 103.92 ? 824 VAL A N   1 
ATOM 1484 C CA  . VAL A 1 243 ? 122.350 112.753 112.026 1.00 103.92 ? 824 VAL A CA  1 
ATOM 1485 C C   . VAL A 1 243 ? 123.182 111.829 111.130 1.00 103.92 ? 824 VAL A C   1 
ATOM 1486 O O   . VAL A 1 243 ? 124.327 111.490 111.455 1.00 103.92 ? 824 VAL A O   1 
ATOM 1487 C CB  . VAL A 1 243 ? 122.077 112.180 113.445 1.00 103.92 ? 824 VAL A CB  1 
ATOM 1488 C CG1 . VAL A 1 243 ? 121.469 110.795 113.441 1.00 103.92 ? 824 VAL A CG1 1 
ATOM 1489 C CG2 . VAL A 1 243 ? 123.281 112.306 114.408 1.00 103.92 ? 824 VAL A CG2 1 
ATOM 1490 N N   . GLN A 1 244 ? 122.653 111.450 109.959 1.00 105.82 ? 825 GLN A N   1 
ATOM 1491 C CA  . GLN A 1 244 ? 123.523 110.858 108.949 1.00 105.82 ? 825 GLN A CA  1 
ATOM 1492 C C   . GLN A 1 244 ? 124.164 111.930 108.078 1.00 105.82 ? 825 GLN A C   1 
ATOM 1493 O O   . GLN A 1 244 ? 125.070 111.638 107.288 1.00 105.82 ? 825 GLN A O   1 
ATOM 1494 C CB  . GLN A 1 244 ? 122.752 109.849 108.099 1.00 105.82 ? 825 GLN A CB  1 
ATOM 1495 C CG  . GLN A 1 244 ? 122.147 108.695 108.892 1.00 105.82 ? 825 GLN A CG  1 
ATOM 1496 C CD  . GLN A 1 244 ? 123.197 107.768 109.486 1.00 105.82 ? 825 GLN A CD  1 
ATOM 1497 O OE1 . GLN A 1 244 ? 123.688 106.858 108.824 1.00 105.82 ? 825 GLN A OE1 1 
ATOM 1498 N NE2 . GLN A 1 244 ? 123.533 107.989 110.749 1.00 105.82 ? 825 GLN A NE2 1 
ATOM 1499 N N   . GLN A 1 245 ? 123.714 113.179 108.205 1.00 113.63 ? 826 GLN A N   1 
ATOM 1500 C CA  . GLN A 1 245 ? 124.248 114.240 107.361 1.00 113.63 ? 826 GLN A CA  1 
ATOM 1501 C C   . GLN A 1 245 ? 125.100 115.252 108.116 1.00 113.63 ? 826 GLN A C   1 
ATOM 1502 O O   . GLN A 1 245 ? 125.367 116.330 107.575 1.00 113.63 ? 826 GLN A O   1 
ATOM 1503 C CB  . GLN A 1 245 ? 123.107 114.959 106.637 1.00 113.63 ? 826 GLN A CB  1 
ATOM 1504 C CG  . GLN A 1 245 ? 122.504 114.148 105.501 1.00 113.63 ? 826 GLN A CG  1 
ATOM 1505 C CD  . GLN A 1 245 ? 121.293 114.815 104.883 1.00 113.63 ? 826 GLN A CD  1 
ATOM 1506 O OE1 . GLN A 1 245 ? 120.910 115.917 105.275 1.00 113.63 ? 826 GLN A OE1 1 
ATOM 1507 N NE2 . GLN A 1 245 ? 120.687 114.152 103.905 1.00 113.63 ? 826 GLN A NE2 1 
ATOM 1508 N N   . PHE A 1 246 ? 125.534 114.947 109.337 1.00 108.64 ? 827 PHE A N   1 
ATOM 1509 C CA  . PHE A 1 246 ? 126.426 115.855 110.047 1.00 108.64 ? 827 PHE A CA  1 
ATOM 1510 C C   . PHE A 1 246 ? 127.860 115.678 109.564 1.00 108.64 ? 827 PHE A C   1 
ATOM 1511 O O   . PHE A 1 246 ? 128.181 114.705 108.875 1.00 108.64 ? 827 PHE A O   1 
ATOM 1512 C CB  . PHE A 1 246 ? 126.353 115.619 111.556 1.00 108.64 ? 827 PHE A CB  1 
ATOM 1513 C CG  . PHE A 1 246 ? 125.157 116.242 112.213 1.00 108.64 ? 827 PHE A CG  1 
ATOM 1514 C CD1 . PHE A 1 246 ? 124.783 117.545 111.915 1.00 108.64 ? 827 PHE A CD1 1 
ATOM 1515 C CD2 . PHE A 1 246 ? 124.426 115.536 113.156 1.00 108.64 ? 827 PHE A CD2 1 
ATOM 1516 C CE1 . PHE A 1 246 ? 123.681 118.122 112.527 1.00 108.64 ? 827 PHE A CE1 1 
ATOM 1517 C CE2 . PHE A 1 246 ? 123.324 116.105 113.775 1.00 108.64 ? 827 PHE A CE2 1 
ATOM 1518 C CZ  . PHE A 1 246 ? 122.953 117.401 113.460 1.00 108.64 ? 827 PHE A CZ  1 
ATOM 1519 N N   . HIS A 1 247 ? 128.713 116.630 109.919 1.00 115.95 ? 828 HIS A N   1 
ATOM 1520 C CA  . HIS A 1 247 ? 130.146 116.514 109.688 1.00 115.95 ? 828 HIS A CA  1 
ATOM 1521 C C   . HIS A 1 247 ? 130.703 115.423 110.599 1.00 115.95 ? 828 HIS A C   1 
ATOM 1522 O O   . HIS A 1 247 ? 130.177 115.238 111.709 1.00 115.95 ? 828 HIS A O   1 
ATOM 1523 C CB  . HIS A 1 247 ? 130.821 117.859 109.956 1.00 115.95 ? 828 HIS A CB  1 
ATOM 1524 C CG  . HIS A 1 247 ? 132.244 117.934 109.497 1.00 115.95 ? 828 HIS A CG  1 
ATOM 1525 N ND1 . HIS A 1 247 ? 133.289 117.398 110.217 1.00 115.95 ? 828 HIS A ND1 1 
ATOM 1526 C CD2 . HIS A 1 247 ? 132.794 118.483 108.388 1.00 115.95 ? 828 HIS A CD2 1 
ATOM 1527 C CE1 . HIS A 1 247 ? 134.422 117.613 109.572 1.00 115.95 ? 828 HIS A CE1 1 
ATOM 1528 N NE2 . HIS A 1 247 ? 134.149 118.269 108.459 1.00 115.95 ? 828 HIS A NE2 1 
ATOM 1529 N N   . PRO A 1 248 ? 131.718 114.637 110.153 1.00 112.12 ? 829 PRO A N   1 
ATOM 1530 C CA  . PRO A 1 248 ? 132.268 113.552 110.986 1.00 112.12 ? 829 PRO A CA  1 
ATOM 1531 C C   . PRO A 1 248 ? 132.882 113.979 112.314 1.00 112.12 ? 829 PRO A C   1 
ATOM 1532 O O   . PRO A 1 248 ? 132.782 113.247 113.304 1.00 112.12 ? 829 PRO A O   1 
ATOM 1533 C CB  . PRO A 1 248 ? 133.332 112.934 110.073 1.00 112.12 ? 829 PRO A CB  1 
ATOM 1534 C CG  . PRO A 1 248 ? 132.794 113.147 108.709 1.00 112.12 ? 829 PRO A CG  1 
ATOM 1535 C CD  . PRO A 1 248 ? 132.142 114.504 108.747 1.00 112.12 ? 829 PRO A CD  1 
ATOM 1536 N N   . ALA A 1 249 ? 133.505 115.160 112.350 1.00 113.25 ? 830 ALA A N   1 
ATOM 1537 C CA  . ALA A 1 249 ? 134.037 115.683 113.605 1.00 113.25 ? 830 ALA A CA  1 
ATOM 1538 C C   . ALA A 1 249 ? 132.912 116.109 114.540 1.00 113.25 ? 830 ALA A C   1 
ATOM 1539 O O   . ALA A 1 249 ? 133.031 116.004 115.766 1.00 113.25 ? 830 ALA A O   1 
ATOM 1540 C CB  . ALA A 1 249 ? 134.983 116.851 113.328 1.00 113.25 ? 830 ALA A CB  1 
ATOM 1541 N N   . VAL A 1 250 ? 131.813 116.610 113.971 1.00 110.85 ? 831 VAL A N   1 
ATOM 1542 C CA  . VAL A 1 250 ? 130.637 116.953 114.766 1.00 110.85 ? 831 VAL A CA  1 
ATOM 1543 C C   . VAL A 1 250 ? 129.940 115.689 115.258 1.00 110.85 ? 831 VAL A C   1 
ATOM 1544 O O   . VAL A 1 250 ? 129.524 115.602 116.420 1.00 110.85 ? 831 VAL A O   1 
ATOM 1545 C CB  . VAL A 1 250 ? 129.694 117.846 113.937 1.00 110.85 ? 831 VAL A CB  1 
ATOM 1546 C CG1 . VAL A 1 250 ? 128.434 118.206 114.718 1.00 110.85 ? 831 VAL A CG1 1 
ATOM 1547 C CG2 . VAL A 1 250 ? 130.428 119.092 113.482 1.00 110.85 ? 831 VAL A CG2 1 
ATOM 1548 N N   . ARG A 1 251 ? 129.823 114.684 114.383 1.00 111.88 ? 832 ARG A N   1 
ATOM 1549 C CA  . ARG A 1 251 ? 129.118 113.450 114.720 1.00 111.88 ? 832 ARG A CA  1 
ATOM 1550 C C   . ARG A 1 251 ? 129.887 112.611 115.734 1.00 111.88 ? 832 ARG A C   1 
ATOM 1551 O O   . ARG A 1 251 ? 129.278 111.971 116.601 1.00 111.88 ? 832 ARG A O   1 
ATOM 1552 C CB  . ARG A 1 251 ? 128.858 112.650 113.441 1.00 111.88 ? 832 ARG A CB  1 
ATOM 1553 C CG  . ARG A 1 251 ? 128.023 111.389 113.608 1.00 111.88 ? 832 ARG A CG  1 
ATOM 1554 C CD  . ARG A 1 251 ? 127.616 110.803 112.260 1.00 111.88 ? 832 ARG A CD  1 
ATOM 1555 N NE  . ARG A 1 251 ? 128.711 110.094 111.606 1.00 111.88 ? 832 ARG A NE  1 
ATOM 1556 C CZ  . ARG A 1 251 ? 129.445 110.590 110.619 1.00 111.88 ? 832 ARG A CZ  1 
ATOM 1557 N NH1 . ARG A 1 251 ? 129.215 111.795 110.125 1.00 111.88 ? 832 ARG A NH1 1 
ATOM 1558 N NH2 . ARG A 1 251 ? 130.436 109.859 110.115 1.00 111.88 ? 832 ARG A NH2 1 
ATOM 1559 N N   . ASN A 1 252 ? 131.218 112.623 115.669 1.00 110.55 ? 833 ASN A N   1 
ATOM 1560 C CA  . ASN A 1 252 ? 132.049 111.871 116.597 1.00 110.55 ? 833 ASN A CA  1 
ATOM 1561 C C   . ASN A 1 252 ? 132.467 112.689 117.816 1.00 110.55 ? 833 ASN A C   1 
ATOM 1562 O O   . ASN A 1 252 ? 133.518 112.412 118.405 1.00 110.55 ? 833 ASN A O   1 
ATOM 1563 C CB  . ASN A 1 252 ? 133.287 111.335 115.874 1.00 110.55 ? 833 ASN A CB  1 
ATOM 1564 C CG  . ASN A 1 252 ? 132.943 110.299 114.823 1.00 110.55 ? 833 ASN A CG  1 
ATOM 1565 O OD1 . ASN A 1 252 ? 132.256 109.317 115.104 1.00 110.55 ? 833 ASN A OD1 1 
ATOM 1566 N ND2 . ASN A 1 252 ? 133.419 110.514 113.603 1.00 110.55 ? 833 ASN A ND2 1 
ATOM 1567 N N   . SER A 1 253 ? 131.673 113.685 118.206 1.00 114.22 ? 834 SER A N   1 
ATOM 1568 C CA  . SER A 1 253 ? 131.991 114.519 119.352 1.00 114.22 ? 834 SER A CA  1 
ATOM 1569 C C   . SER A 1 253 ? 131.421 113.907 120.631 1.00 114.22 ? 834 SER A C   1 
ATOM 1570 O O   . SER A 1 253 ? 130.974 112.758 120.660 1.00 114.22 ? 834 SER A O   1 
ATOM 1571 C CB  . SER A 1 253 ? 131.469 115.939 119.142 1.00 114.22 ? 834 SER A CB  1 
ATOM 1572 O OG  . SER A 1 253 ? 130.056 115.957 119.111 1.00 114.22 ? 834 SER A OG  1 
ATOM 1573 N N   . SER A 1 254 ? 131.436 114.694 121.709 1.00 117.12 ? 835 SER A N   1 
ATOM 1574 C CA  . SER A 1 254 ? 131.090 114.156 123.021 1.00 117.12 ? 835 SER A CA  1 
ATOM 1575 C C   . SER A 1 254 ? 129.587 114.196 123.275 1.00 117.12 ? 835 SER A C   1 
ATOM 1576 O O   . SER A 1 254 ? 129.033 113.283 123.899 1.00 117.12 ? 835 SER A O   1 
ATOM 1577 C CB  . SER A 1 254 ? 131.836 114.926 124.111 1.00 117.12 ? 835 SER A CB  1 
ATOM 1578 O OG  . SER A 1 254 ? 133.226 114.655 124.067 1.00 117.12 ? 835 SER A OG  1 
ATOM 1579 N N   . GLU A 1 255 ? 128.908 115.243 122.806 1.00 114.30 ? 836 GLU A N   1 
ATOM 1580 C CA  . GLU A 1 255 ? 127.521 115.485 123.182 1.00 114.30 ? 836 GLU A CA  1 
ATOM 1581 C C   . GLU A 1 255 ? 126.503 115.093 122.119 1.00 114.30 ? 836 GLU A C   1 
ATOM 1582 O O   . GLU A 1 255 ? 125.320 114.949 122.447 1.00 114.30 ? 836 GLU A O   1 
ATOM 1583 C CB  . GLU A 1 255 ? 127.324 116.961 123.560 1.00 114.30 ? 836 GLU A CB  1 
ATOM 1584 C CG  . GLU A 1 255 ? 127.669 117.953 122.461 1.00 114.30 ? 836 GLU A CG  1 
ATOM 1585 C CD  . GLU A 1 255 ? 129.086 118.489 122.578 1.00 114.30 ? 836 GLU A CD  1 
ATOM 1586 O OE1 . GLU A 1 255 ? 129.899 117.883 123.307 1.00 114.30 ? 836 GLU A OE1 1 
ATOM 1587 O OE2 . GLU A 1 255 ? 129.385 119.522 121.943 1.00 114.30 ? 836 GLU A OE2 1 
ATOM 1588 N N   . VAL A 1 256 ? 126.913 114.934 120.859 1.00 109.74 ? 837 VAL A N   1 
ATOM 1589 C CA  . VAL A 1 256 ? 126.000 114.404 119.851 1.00 109.74 ? 837 VAL A CA  1 
ATOM 1590 C C   . VAL A 1 256 ? 125.770 112.913 120.080 1.00 109.74 ? 837 VAL A C   1 
ATOM 1591 O O   . VAL A 1 256 ? 124.651 112.408 119.922 1.00 109.74 ? 837 VAL A O   1 
ATOM 1592 C CB  . VAL A 1 256 ? 126.537 114.710 118.440 1.00 109.74 ? 837 VAL A CB  1 
ATOM 1593 C CG1 . VAL A 1 256 ? 125.552 114.273 117.365 1.00 109.74 ? 837 VAL A CG1 1 
ATOM 1594 C CG2 . VAL A 1 256 ? 126.815 116.196 118.310 1.00 109.74 ? 837 VAL A CG2 1 
ATOM 1595 N N   . LYS A 1 257 ? 126.816 112.191 120.495 1.00 110.00 ? 838 LYS A N   1 
ATOM 1596 C CA  . LYS A 1 257 ? 126.654 110.798 120.901 1.00 110.00 ? 838 LYS A CA  1 
ATOM 1597 C C   . LYS A 1 257 ? 125.870 110.661 122.200 1.00 110.00 ? 838 LYS A C   1 
ATOM 1598 O O   . LYS A 1 257 ? 125.282 109.603 122.446 1.00 110.00 ? 838 LYS A O   1 
ATOM 1599 C CB  . LYS A 1 257 ? 128.021 110.128 121.044 1.00 110.00 ? 838 LYS A CB  1 
ATOM 1600 C CG  . LYS A 1 257 ? 128.722 109.867 119.723 1.00 110.00 ? 838 LYS A CG  1 
ATOM 1601 C CD  . LYS A 1 257 ? 130.038 109.139 119.933 1.00 110.00 ? 838 LYS A CD  1 
ATOM 1602 C CE  . LYS A 1 257 ? 130.742 108.877 118.612 1.00 110.00 ? 838 LYS A CE  1 
ATOM 1603 N NZ  . LYS A 1 257 ? 130.008 107.898 117.764 1.00 110.00 ? 838 LYS A NZ  1 
ATOM 1604 N N   . PHE A 1 258 ? 125.858 111.704 123.035 1.00 99.91  ? 839 PHE A N   1 
ATOM 1605 C CA  . PHE A 1 258 ? 124.945 111.748 124.171 1.00 99.91  ? 839 PHE A CA  1 
ATOM 1606 C C   . PHE A 1 258 ? 123.503 111.890 123.694 1.00 99.91  ? 839 PHE A C   1 
ATOM 1607 O O   . PHE A 1 258 ? 122.579 111.327 124.295 1.00 99.91  ? 839 PHE A O   1 
ATOM 1608 C CB  . PHE A 1 258 ? 125.345 112.900 125.101 1.00 99.91  ? 839 PHE A CB  1 
ATOM 1609 C CG  . PHE A 1 258 ? 124.242 113.380 126.003 1.00 99.91  ? 839 PHE A CG  1 
ATOM 1610 C CD1 . PHE A 1 258 ? 123.861 112.630 127.106 1.00 99.91  ? 839 PHE A CD1 1 
ATOM 1611 C CD2 . PHE A 1 258 ? 123.596 114.588 125.761 1.00 99.91  ? 839 PHE A CD2 1 
ATOM 1612 C CE1 . PHE A 1 258 ? 122.850 113.067 127.945 1.00 99.91  ? 839 PHE A CE1 1 
ATOM 1613 C CE2 . PHE A 1 258 ? 122.577 115.023 126.592 1.00 99.91  ? 839 PHE A CE2 1 
ATOM 1614 C CZ  . PHE A 1 258 ? 122.208 114.263 127.687 1.00 99.91  ? 839 PHE A CZ  1 
ATOM 1615 N N   . ALA A 1 259 ? 123.297 112.641 122.607 1.00 101.60 ? 840 ALA A N   1 
ATOM 1616 C CA  . ALA A 1 259 ? 121.958 112.829 122.052 1.00 101.60 ? 840 ALA A CA  1 
ATOM 1617 C C   . ALA A 1 259 ? 121.443 111.556 121.389 1.00 101.60 ? 840 ALA A C   1 
ATOM 1618 O O   . ALA A 1 259 ? 120.235 111.281 121.408 1.00 101.60 ? 840 ALA A O   1 
ATOM 1619 C CB  . ALA A 1 259 ? 121.975 113.981 121.051 1.00 101.60 ? 840 ALA A CB  1 
ATOM 1620 N N   . VAL A 1 260 ? 122.351 110.781 120.783 1.00 104.08 ? 841 VAL A N   1 
ATOM 1621 C CA  . VAL A 1 260 ? 122.016 109.461 120.245 1.00 104.08 ? 841 VAL A CA  1 
ATOM 1622 C C   . VAL A 1 260 ? 121.558 108.523 121.358 1.00 104.08 ? 841 VAL A C   1 
ATOM 1623 O O   . VAL A 1 260 ? 120.610 107.746 121.177 1.00 104.08 ? 841 VAL A O   1 
ATOM 1624 C CB  . VAL A 1 260 ? 123.229 108.904 119.462 1.00 104.08 ? 841 VAL A CB  1 
ATOM 1625 C CG1 . VAL A 1 260 ? 123.004 107.475 118.989 1.00 104.08 ? 841 VAL A CG1 1 
ATOM 1626 C CG2 . VAL A 1 260 ? 123.520 109.781 118.256 1.00 104.08 ? 841 VAL A CG2 1 
ATOM 1627 N N   . GLN A 1 261 ? 122.177 108.626 122.541 1.00 101.94 ? 842 GLN A N   1 
ATOM 1628 C CA  . GLN A 1 261 ? 121.762 107.827 123.693 1.00 101.94 ? 842 GLN A CA  1 
ATOM 1629 C C   . GLN A 1 261 ? 120.373 108.226 124.186 1.00 101.94 ? 842 GLN A C   1 
ATOM 1630 O O   . GLN A 1 261 ? 119.582 107.365 124.586 1.00 101.94 ? 842 GLN A O   1 
ATOM 1631 C CB  . GLN A 1 261 ? 122.787 107.962 124.818 1.00 101.94 ? 842 GLN A CB  1 
ATOM 1632 C CG  . GLN A 1 261 ? 124.095 107.217 124.578 1.00 101.94 ? 842 GLN A CG  1 
ATOM 1633 C CD  . GLN A 1 261 ? 124.051 105.768 125.032 1.00 101.94 ? 842 GLN A CD  1 
ATOM 1634 O OE1 . GLN A 1 261 ? 123.276 104.963 124.516 1.00 101.94 ? 842 GLN A OE1 1 
ATOM 1635 N NE2 . GLN A 1 261 ? 124.887 105.432 126.007 1.00 101.94 ? 842 GLN A NE2 1 
ATOM 1636 N N   . ALA A 1 262 ? 120.046 109.522 124.132 1.00 98.53  ? 843 ALA A N   1 
ATOM 1637 C CA  . ALA A 1 262 ? 118.715 109.978 124.530 1.00 98.53  ? 843 ALA A CA  1 
ATOM 1638 C C   . ALA A 1 262 ? 117.650 109.531 123.531 1.00 98.53  ? 843 ALA A C   1 
ATOM 1639 O O   . ALA A 1 262 ? 116.536 109.148 123.920 1.00 98.53  ? 843 ALA A O   1 
ATOM 1640 C CB  . ALA A 1 262 ? 118.707 111.499 124.682 1.00 98.53  ? 843 ALA A CB  1 
ATOM 1641 N N   . PHE A 1 263 ? 117.980 109.568 122.235 1.00 96.19  ? 844 PHE A N   1 
ATOM 1642 C CA  . PHE A 1 263 ? 117.034 109.111 121.219 1.00 96.19  ? 844 PHE A CA  1 
ATOM 1643 C C   . PHE A 1 263 ? 116.845 107.599 121.276 1.00 96.19  ? 844 PHE A C   1 
ATOM 1644 O O   . PHE A 1 263 ? 115.758 107.090 120.977 1.00 96.19  ? 844 PHE A O   1 
ATOM 1645 C CB  . PHE A 1 263 ? 117.491 109.534 119.824 1.00 96.19  ? 844 PHE A CB  1 
ATOM 1646 C CG  . PHE A 1 263 ? 116.433 109.363 118.772 1.00 96.19  ? 844 PHE A CG  1 
ATOM 1647 C CD1 . PHE A 1 263 ? 115.403 110.287 118.654 1.00 96.19  ? 844 PHE A CD1 1 
ATOM 1648 C CD2 . PHE A 1 263 ? 116.453 108.271 117.915 1.00 96.19  ? 844 PHE A CD2 1 
ATOM 1649 C CE1 . PHE A 1 263 ? 114.419 110.132 117.691 1.00 96.19  ? 844 PHE A CE1 1 
ATOM 1650 C CE2 . PHE A 1 263 ? 115.468 108.106 116.955 1.00 96.19  ? 844 PHE A CE2 1 
ATOM 1651 C CZ  . PHE A 1 263 ? 114.454 109.042 116.839 1.00 96.19  ? 844 PHE A CZ  1 
ATOM 1652 N N   . ALA A 1 264 ? 117.893 106.864 121.656 1.00 94.98  ? 845 ALA A N   1 
ATOM 1653 C CA  . ALA A 1 264 ? 117.744 105.430 121.878 1.00 94.98  ? 845 ALA A CA  1 
ATOM 1654 C C   . ALA A 1 264 ? 116.977 105.150 123.164 1.00 94.98  ? 845 ALA A C   1 
ATOM 1655 O O   . ALA A 1 264 ? 116.329 104.105 123.292 1.00 94.98  ? 845 ALA A O   1 
ATOM 1656 C CB  . ALA A 1 264 ? 119.116 104.758 121.914 1.00 94.98  ? 845 ALA A CB  1 
ATOM 1657 N N   . ALA A 1 265 ? 117.049 106.067 124.132 1.00 92.90  ? 846 ALA A N   1 
ATOM 1658 C CA  . ALA A 1 265 ? 116.266 105.920 125.354 1.00 92.90  ? 846 ALA A CA  1 
ATOM 1659 C C   . ALA A 1 265 ? 114.786 106.174 125.100 1.00 92.90  ? 846 ALA A C   1 
ATOM 1660 O O   . ALA A 1 265 ? 113.930 105.621 125.801 1.00 92.90  ? 846 ALA A O   1 
ATOM 1661 C CB  . ALA A 1 265 ? 116.796 106.861 126.433 1.00 92.90  ? 846 ALA A CB  1 
ATOM 1662 N N   . LEU A 1 266 ? 114.461 107.018 124.115 1.00 88.00  ? 847 LEU A N   1 
ATOM 1663 C CA  . LEU A 1 266 ? 113.054 107.236 123.781 1.00 88.00  ? 847 LEU A CA  1 
ATOM 1664 C C   . LEU A 1 266 ? 112.438 106.033 123.074 1.00 88.00  ? 847 LEU A C   1 
ATOM 1665 O O   . LEU A 1 266 ? 111.487 105.427 123.581 1.00 88.00  ? 847 LEU A O   1 
ATOM 1666 C CB  . LEU A 1 266 ? 112.883 108.466 122.893 1.00 88.00  ? 847 LEU A CB  1 
ATOM 1667 C CG  . LEU A 1 266 ? 111.392 108.707 122.605 1.00 88.00  ? 847 LEU A CG  1 
ATOM 1668 C CD1 . LEU A 1 266 ? 110.594 109.013 123.862 1.00 88.00  ? 847 LEU A CD1 1 
ATOM 1669 C CD2 . LEU A 1 266 ? 111.140 109.738 121.526 1.00 88.00  ? 847 LEU A CD2 1 
ATOM 1670 N N   . ASN A 1 267 ? 112.958 105.685 121.895 1.00 86.57  ? 848 ASN A N   1 
ATOM 1671 C CA  . ASN A 1 267 ? 112.213 104.842 120.964 1.00 86.57  ? 848 ASN A CA  1 
ATOM 1672 C C   . ASN A 1 267 ? 112.281 103.370 121.352 1.00 86.57  ? 848 ASN A C   1 
ATOM 1673 O O   . ASN A 1 267 ? 111.441 102.565 120.932 1.00 86.57  ? 848 ASN A O   1 
ATOM 1674 C CB  . ASN A 1 267 ? 112.734 105.060 119.544 1.00 86.57  ? 848 ASN A CB  1 
ATOM 1675 C CG  . ASN A 1 267 ? 112.339 106.411 118.986 1.00 86.57  ? 848 ASN A CG  1 
ATOM 1676 O OD1 . ASN A 1 267 ? 113.004 107.416 119.235 1.00 86.57  ? 848 ASN A OD1 1 
ATOM 1677 N ND2 . ASN A 1 267 ? 111.249 106.444 118.230 1.00 86.57  ? 848 ASN A ND2 1 
ATOM 1678 N N   . SER A 1 268 ? 113.271 102.995 122.159 1.00 88.45  ? 849 SER A N   1 
ATOM 1679 C CA  . SER A 1 268 ? 113.340 101.629 122.662 1.00 88.45  ? 849 SER A CA  1 
ATOM 1680 C C   . SER A 1 268 ? 112.591 101.518 123.983 1.00 88.45  ? 849 SER A C   1 
ATOM 1681 O O   . SER A 1 268 ? 112.446 100.413 124.519 1.00 88.45  ? 849 SER A O   1 
ATOM 1682 C CB  . SER A 1 268 ? 114.794 101.184 122.831 1.00 88.45  ? 849 SER A CB  1 
ATOM 1683 O OG  . SER A 1 268 ? 114.882 100.030 123.647 1.00 88.45  ? 849 SER A OG  1 
ATOM 1684 N N   . ASN A 1 269 ? 112.114 102.670 124.479 1.00 88.39  ? 850 ASN A N   1 
ATOM 1685 C CA  . ASN A 1 269 ? 111.410 102.837 125.759 1.00 88.39  ? 850 ASN A CA  1 
ATOM 1686 C C   . ASN A 1 269 ? 112.261 102.308 126.917 1.00 88.39  ? 850 ASN A C   1 
ATOM 1687 O O   . ASN A 1 269 ? 111.819 101.515 127.751 1.00 88.39  ? 850 ASN A O   1 
ATOM 1688 C CB  . ASN A 1 269 ? 110.015 102.192 125.716 1.00 88.39  ? 850 ASN A CB  1 
ATOM 1689 C CG  . ASN A 1 269 ? 109.094 102.683 126.825 1.00 88.39  ? 850 ASN A CG  1 
ATOM 1690 O OD1 . ASN A 1 269 ? 109.471 103.520 127.645 1.00 88.39  ? 850 ASN A OD1 1 
ATOM 1691 N ND2 . ASN A 1 269 ? 107.874 102.160 126.848 1.00 88.39  ? 850 ASN A ND2 1 
ATOM 1692 N N   . ASN A 1 270 ? 113.518 102.745 126.941 1.00 89.09  ? 851 ASN A N   1 
ATOM 1693 C CA  . ASN A 1 270 ? 114.472 102.370 127.980 1.00 89.09  ? 851 ASN A CA  1 
ATOM 1694 C C   . ASN A 1 270 ? 114.521 103.517 128.983 1.00 89.09  ? 851 ASN A C   1 
ATOM 1695 O O   . ASN A 1 270 ? 115.361 104.414 128.882 1.00 89.09  ? 851 ASN A O   1 
ATOM 1696 C CB  . ASN A 1 270 ? 115.844 102.081 127.380 1.00 89.09  ? 851 ASN A CB  1 
ATOM 1697 C CG  . ASN A 1 270 ? 116.672 101.149 128.240 1.00 89.09  ? 851 ASN A CG  1 
ATOM 1698 O OD1 . ASN A 1 270 ? 116.261 100.767 129.334 1.00 89.09  ? 851 ASN A OD1 1 
ATOM 1699 N ND2 . ASN A 1 270 ? 117.844 100.773 127.745 1.00 89.09  ? 851 ASN A ND2 1 
ATOM 1700 N N   . PHE A 1 271 ? 113.609 103.482 129.956 1.00 83.58  ? 852 PHE A N   1 
ATOM 1701 C CA  . PHE A 1 271 ? 113.469 104.599 130.884 1.00 83.58  ? 852 PHE A CA  1 
ATOM 1702 C C   . PHE A 1 271 ? 114.512 104.550 131.996 1.00 83.58  ? 852 PHE A C   1 
ATOM 1703 O O   . PHE A 1 271 ? 114.723 105.549 132.693 1.00 83.58  ? 852 PHE A O   1 
ATOM 1704 C CB  . PHE A 1 271 ? 112.046 104.635 131.455 1.00 83.58  ? 852 PHE A CB  1 
ATOM 1705 C CG  . PHE A 1 271 ? 111.722 103.512 132.414 1.00 83.58  ? 852 PHE A CG  1 
ATOM 1706 C CD1 . PHE A 1 271 ? 111.346 102.260 131.940 1.00 83.58  ? 852 PHE A CD1 1 
ATOM 1707 C CD2 . PHE A 1 271 ? 111.745 103.723 133.787 1.00 83.58  ? 852 PHE A CD2 1 
ATOM 1708 C CE1 . PHE A 1 271 ? 111.030 101.234 132.816 1.00 83.58  ? 852 PHE A CE1 1 
ATOM 1709 C CE2 . PHE A 1 271 ? 111.433 102.699 134.667 1.00 83.58  ? 852 PHE A CE2 1 
ATOM 1710 C CZ  . PHE A 1 271 ? 111.076 101.454 134.180 1.00 83.58  ? 852 PHE A CZ  1 
ATOM 1711 N N   . VAL A 1 272 ? 115.160 103.398 132.191 1.00 82.32  ? 853 VAL A N   1 
ATOM 1712 C CA  . VAL A 1 272 ? 116.238 103.305 133.170 1.00 82.32  ? 853 VAL A CA  1 
ATOM 1713 C C   . VAL A 1 272 ? 117.474 104.060 132.698 1.00 82.32  ? 853 VAL A C   1 
ATOM 1714 O O   . VAL A 1 272 ? 118.073 104.813 133.473 1.00 82.32  ? 853 VAL A O   1 
ATOM 1715 C CB  . VAL A 1 272 ? 116.529 101.819 133.481 1.00 82.32  ? 853 VAL A CB  1 
ATOM 1716 C CG1 . VAL A 1 272 ? 117.837 101.643 134.241 1.00 82.32  ? 853 VAL A CG1 1 
ATOM 1717 C CG2 . VAL A 1 272 ? 115.392 101.247 134.302 1.00 82.32  ? 853 VAL A CG2 1 
ATOM 1718 N N   . ARG A 1 273 ? 117.821 103.953 131.414 1.00 89.00  ? 854 ARG A N   1 
ATOM 1719 C CA  . ARG A 1 273 ? 118.935 104.698 130.837 1.00 89.00  ? 854 ARG A CA  1 
ATOM 1720 C C   . ARG A 1 273 ? 118.494 106.055 130.286 1.00 89.00  ? 854 ARG A C   1 
ATOM 1721 O O   . ARG A 1 273 ? 119.099 106.582 129.347 1.00 89.00  ? 854 ARG A O   1 
ATOM 1722 C CB  . ARG A 1 273 ? 119.623 103.865 129.754 1.00 89.00  ? 854 ARG A CB  1 
ATOM 1723 C CG  . ARG A 1 273 ? 121.138 104.039 129.692 1.00 89.00  ? 854 ARG A CG  1 
ATOM 1724 C CD  . ARG A 1 273 ? 121.719 103.454 128.408 1.00 89.00  ? 854 ARG A CD  1 
ATOM 1725 N NE  . ARG A 1 273 ? 121.596 102.001 128.340 1.00 89.00  ? 854 ARG A NE  1 
ATOM 1726 C CZ  . ARG A 1 273 ? 122.359 101.136 128.996 1.00 89.00  ? 854 ARG A CZ  1 
ATOM 1727 N NH1 . ARG A 1 273 ? 123.367 101.534 129.757 1.00 89.00  ? 854 ARG A NH1 1 
ATOM 1728 N NH2 . ARG A 1 273 ? 122.116 99.835  128.873 1.00 89.00  ? 854 ARG A NH2 1 
ATOM 1729 N N   . PHE A 1 274 ? 117.428 106.622 130.849 1.00 83.12  ? 855 PHE A N   1 
ATOM 1730 C CA  . PHE A 1 274 ? 116.979 107.971 130.532 1.00 83.12  ? 855 PHE A CA  1 
ATOM 1731 C C   . PHE A 1 274 ? 117.120 108.865 131.762 1.00 83.12  ? 855 PHE A C   1 
ATOM 1732 O O   . PHE A 1 274 ? 117.766 109.914 131.699 1.00 83.12  ? 855 PHE A O   1 
ATOM 1733 C CB  . PHE A 1 274 ? 115.534 107.928 130.031 1.00 83.12  ? 855 PHE A CB  1 
ATOM 1734 C CG  . PHE A 1 274 ? 114.982 109.264 129.637 1.00 83.12  ? 855 PHE A CG  1 
ATOM 1735 C CD1 . PHE A 1 274 ? 115.338 109.850 128.431 1.00 83.12  ? 855 PHE A CD1 1 
ATOM 1736 C CD2 . PHE A 1 274 ? 114.091 109.929 130.469 1.00 83.12  ? 855 PHE A CD2 1 
ATOM 1737 C CE1 . PHE A 1 274 ? 114.822 111.079 128.065 1.00 83.12  ? 855 PHE A CE1 1 
ATOM 1738 C CE2 . PHE A 1 274 ? 113.575 111.159 130.113 1.00 83.12  ? 855 PHE A CE2 1 
ATOM 1739 C CZ  . PHE A 1 274 ? 113.937 111.731 128.909 1.00 83.12  ? 855 PHE A CZ  1 
ATOM 1740 N N   . PHE A 1 275 ? 116.540 108.461 132.893 1.00 82.19  ? 856 PHE A N   1 
ATOM 1741 C CA  . PHE A 1 275 ? 116.647 109.259 134.108 1.00 82.19  ? 856 PHE A CA  1 
ATOM 1742 C C   . PHE A 1 275 ? 118.017 109.111 134.756 1.00 82.19  ? 856 PHE A C   1 
ATOM 1743 O O   . PHE A 1 275 ? 118.468 110.004 135.480 1.00 82.19  ? 856 PHE A O   1 
ATOM 1744 C CB  . PHE A 1 275 ? 115.534 108.868 135.078 1.00 82.19  ? 856 PHE A CB  1 
ATOM 1745 C CG  . PHE A 1 275 ? 114.163 109.229 134.591 1.00 82.19  ? 856 PHE A CG  1 
ATOM 1746 C CD1 . PHE A 1 275 ? 113.916 110.482 134.048 1.00 82.19  ? 856 PHE A CD1 1 
ATOM 1747 C CD2 . PHE A 1 275 ? 113.127 108.311 134.650 1.00 82.19  ? 856 PHE A CD2 1 
ATOM 1748 C CE1 . PHE A 1 275 ? 112.652 110.819 133.595 1.00 82.19  ? 856 PHE A CE1 1 
ATOM 1749 C CE2 . PHE A 1 275 ? 111.861 108.639 134.200 1.00 82.19  ? 856 PHE A CE2 1 
ATOM 1750 C CZ  . PHE A 1 275 ? 111.624 109.895 133.671 1.00 82.19  ? 856 PHE A CZ  1 
ATOM 1751 N N   . LYS A 1 276 ? 118.696 107.986 134.517 1.00 86.43  ? 857 LYS A N   1 
ATOM 1752 C CA  . LYS A 1 276 ? 120.093 107.887 134.921 1.00 86.43  ? 857 LYS A CA  1 
ATOM 1753 C C   . LYS A 1 276 ? 121.006 108.647 133.971 1.00 86.43  ? 857 LYS A C   1 
ATOM 1754 O O   . LYS A 1 276 ? 122.116 109.025 134.359 1.00 86.43  ? 857 LYS A O   1 
ATOM 1755 C CB  . LYS A 1 276 ? 120.527 106.423 134.999 1.00 86.43  ? 857 LYS A CB  1 
ATOM 1756 C CG  . LYS A 1 276 ? 120.561 105.854 136.407 1.00 86.43  ? 857 LYS A CG  1 
ATOM 1757 C CD  . LYS A 1 276 ? 121.149 104.452 136.416 1.00 86.43  ? 857 LYS A CD  1 
ATOM 1758 C CE  . LYS A 1 276 ? 121.273 103.911 137.831 1.00 86.43  ? 857 LYS A CE  1 
ATOM 1759 N NZ  . LYS A 1 276 ? 121.712 102.489 137.845 1.00 86.43  ? 857 LYS A NZ  1 
ATOM 1760 N N   . LEU A 1 277 ? 120.563 108.871 132.736 1.00 87.76  ? 858 LEU A N   1 
ATOM 1761 C CA  . LEU A 1 277 ? 121.298 109.656 131.757 1.00 87.76  ? 858 LEU A CA  1 
ATOM 1762 C C   . LEU A 1 277 ? 121.158 111.156 131.979 1.00 87.76  ? 858 LEU A C   1 
ATOM 1763 O O   . LEU A 1 277 ? 122.106 111.901 131.706 1.00 87.76  ? 858 LEU A O   1 
ATOM 1764 C CB  . LEU A 1 277 ? 120.822 109.285 130.346 1.00 87.76  ? 858 LEU A CB  1 
ATOM 1765 C CG  . LEU A 1 277 ? 121.463 109.925 129.115 1.00 87.76  ? 858 LEU A CG  1 
ATOM 1766 C CD1 . LEU A 1 277 ? 122.857 109.366 128.879 1.00 87.76  ? 858 LEU A CD1 1 
ATOM 1767 C CD2 . LEU A 1 277 ? 120.587 109.732 127.888 1.00 87.76  ? 858 LEU A CD2 1 
ATOM 1768 N N   . VAL A 1 278 ? 120.009 111.610 132.490 1.00 81.53  ? 859 VAL A N   1 
ATOM 1769 C CA  . VAL A 1 278 ? 119.774 113.045 132.648 1.00 81.53  ? 859 VAL A CA  1 
ATOM 1770 C C   . VAL A 1 278 ? 120.555 113.595 133.845 1.00 81.53  ? 859 VAL A C   1 
ATOM 1771 O O   . VAL A 1 278 ? 120.820 114.800 133.933 1.00 81.53  ? 859 VAL A O   1 
ATOM 1772 C CB  . VAL A 1 278 ? 118.259 113.332 132.746 1.00 81.53  ? 859 VAL A CB  1 
ATOM 1773 C CG1 . VAL A 1 278 ? 117.687 112.969 134.115 1.00 81.53  ? 859 VAL A CG1 1 
ATOM 1774 C CG2 . VAL A 1 278 ? 117.931 114.777 132.367 1.00 81.53  ? 859 VAL A CG2 1 
ATOM 1775 N N   . GLN A 1 279 ? 120.975 112.719 134.766 1.00 86.97  ? 860 GLN A N   1 
ATOM 1776 C CA  . GLN A 1 279 ? 121.802 113.174 135.880 1.00 86.97  ? 860 GLN A CA  1 
ATOM 1777 C C   . GLN A 1 279 ? 123.264 113.321 135.477 1.00 86.97  ? 860 GLN A C   1 
ATOM 1778 O O   . GLN A 1 279 ? 124.043 113.952 136.201 1.00 86.97  ? 860 GLN A O   1 
ATOM 1779 C CB  . GLN A 1 279 ? 121.678 112.217 137.065 1.00 86.97  ? 860 GLN A CB  1 
ATOM 1780 C CG  . GLN A 1 279 ? 120.254 111.938 137.501 1.00 86.97  ? 860 GLN A CG  1 
ATOM 1781 C CD  . GLN A 1 279 ? 120.175 110.872 138.577 1.00 86.97  ? 860 GLN A CD  1 
ATOM 1782 O OE1 . GLN A 1 279 ? 120.755 111.016 139.653 1.00 86.97  ? 860 GLN A OE1 1 
ATOM 1783 N NE2 . GLN A 1 279 ? 119.457 109.793 138.289 1.00 86.97  ? 860 GLN A NE2 1 
ATOM 1784 N N   . SER A 1 280 ? 123.655 112.751 134.341 1.00 90.60  ? 861 SER A N   1 
ATOM 1785 C CA  . SER A 1 280 ? 125.026 112.841 133.858 1.00 90.60  ? 861 SER A CA  1 
ATOM 1786 C C   . SER A 1 280 ? 125.216 113.922 132.802 1.00 90.60  ? 861 SER A C   1 
ATOM 1787 O O   . SER A 1 280 ? 126.140 113.815 131.988 1.00 90.60  ? 861 SER A O   1 
ATOM 1788 C CB  . SER A 1 280 ? 125.474 111.489 133.298 1.00 90.60  ? 861 SER A CB  1 
ATOM 1789 O OG  . SER A 1 280 ? 126.792 111.562 132.784 1.00 90.60  ? 861 SER A OG  1 
ATOM 1790 N N   . ALA A 1 281 ? 124.373 114.952 132.793 1.00 88.95  ? 862 ALA A N   1 
ATOM 1791 C CA  . ALA A 1 281 ? 124.441 116.009 131.796 1.00 88.95  ? 862 ALA A CA  1 
ATOM 1792 C C   . ALA A 1 281 ? 124.524 117.363 132.483 1.00 88.95  ? 862 ALA A C   1 
ATOM 1793 O O   . ALA A 1 281 ? 124.496 117.457 133.713 1.00 88.95  ? 862 ALA A O   1 
ATOM 1794 C CB  . ALA A 1 281 ? 123.229 115.974 130.857 1.00 88.95  ? 862 ALA A CB  1 
ATOM 1795 N N   . SER A 1 282 ? 124.625 118.413 131.672 1.00 96.38  ? 863 SER A N   1 
ATOM 1796 C CA  . SER A 1 282 ? 124.717 119.769 132.190 1.00 96.38  ? 863 SER A CA  1 
ATOM 1797 C C   . SER A 1 282 ? 123.333 120.301 132.564 1.00 96.38  ? 863 SER A C   1 
ATOM 1798 O O   . SER A 1 282 ? 122.325 119.589 132.518 1.00 96.38  ? 863 SER A O   1 
ATOM 1799 C CB  . SER A 1 282 ? 125.383 120.687 131.166 1.00 96.38  ? 863 SER A CB  1 
ATOM 1800 O OG  . SER A 1 282 ? 124.566 120.849 130.021 1.00 96.38  ? 863 SER A OG  1 
ATOM 1801 N N   . TYR A 1 283 ? 123.298 121.578 132.949 1.00 95.51  ? 864 TYR A N   1 
ATOM 1802 C CA  . TYR A 1 283 ? 122.070 122.230 133.395 1.00 95.51  ? 864 TYR A CA  1 
ATOM 1803 C C   . TYR A 1 283 ? 121.056 122.429 132.275 1.00 95.51  ? 864 TYR A C   1 
ATOM 1804 O O   . TYR A 1 283 ? 119.869 122.138 132.453 1.00 95.51  ? 864 TYR A O   1 
ATOM 1805 C CB  . TYR A 1 283 ? 122.382 123.585 134.030 1.00 95.51  ? 864 TYR A CB  1 
ATOM 1806 C CG  . TYR A 1 283 ? 121.140 124.343 134.435 1.00 95.51  ? 864 TYR A CG  1 
ATOM 1807 C CD1 . TYR A 1 283 ? 120.229 123.796 135.335 1.00 95.51  ? 864 TYR A CD1 1 
ATOM 1808 C CD2 . TYR A 1 283 ? 120.864 125.597 133.897 1.00 95.51  ? 864 TYR A CD2 1 
ATOM 1809 C CE1 . TYR A 1 283 ? 119.083 124.484 135.700 1.00 95.51  ? 864 TYR A CE1 1 
ATOM 1810 C CE2 . TYR A 1 283 ? 119.720 126.293 134.256 1.00 95.51  ? 864 TYR A CE2 1 
ATOM 1811 C CZ  . TYR A 1 283 ? 118.836 125.730 135.157 1.00 95.51  ? 864 TYR A CZ  1 
ATOM 1812 O OH  . TYR A 1 283 ? 117.700 126.415 135.518 1.00 95.51  ? 864 TYR A OH  1 
ATOM 1813 N N   . LEU A 1 284 ? 121.511 122.943 131.130 1.00 93.91  ? 865 LEU A N   1 
ATOM 1814 C CA  . LEU A 1 284 ? 120.592 123.272 130.043 1.00 93.91  ? 865 LEU A CA  1 
ATOM 1815 C C   . LEU A 1 284 ? 120.080 122.011 129.353 1.00 93.91  ? 865 LEU A C   1 
ATOM 1816 O O   . LEU A 1 284 ? 118.905 121.933 128.963 1.00 93.91  ? 865 LEU A O   1 
ATOM 1817 C CB  . LEU A 1 284 ? 121.282 124.205 129.052 1.00 93.91  ? 865 LEU A CB  1 
ATOM 1818 C CG  . LEU A 1 284 ? 121.806 125.521 129.623 1.00 93.91  ? 865 LEU A CG  1 
ATOM 1819 C CD1 . LEU A 1 284 ? 122.725 126.209 128.630 1.00 93.91  ? 865 LEU A CD1 1 
ATOM 1820 C CD2 . LEU A 1 284 ? 120.644 126.418 129.996 1.00 93.91  ? 865 LEU A CD2 1 
ATOM 1821 N N   . ASN A 1 285 ? 120.957 121.007 129.218 1.00 91.29  ? 866 ASN A N   1 
ATOM 1822 C CA  . ASN A 1 285 ? 120.578 119.691 128.710 1.00 91.29  ? 866 ASN A CA  1 
ATOM 1823 C C   . ASN A 1 285 ? 119.551 119.008 129.604 1.00 91.29  ? 866 ASN A C   1 
ATOM 1824 O O   . ASN A 1 285 ? 118.680 118.288 129.107 1.00 91.29  ? 866 ASN A O   1 
ATOM 1825 C CB  . ASN A 1 285 ? 121.828 118.818 128.581 1.00 91.29  ? 866 ASN A CB  1 
ATOM 1826 C CG  . ASN A 1 285 ? 122.403 118.815 127.180 1.00 91.29  ? 866 ASN A CG  1 
ATOM 1827 O OD1 . ASN A 1 285 ? 121.876 119.455 126.279 1.00 91.29  ? 866 ASN A OD1 1 
ATOM 1828 N ND2 . ASN A 1 285 ? 123.525 118.130 127.005 1.00 91.29  ? 866 ASN A ND2 1 
ATOM 1829 N N   . ALA A 1 286 ? 119.628 119.231 130.918 1.00 93.41  ? 867 ALA A N   1 
ATOM 1830 C CA  . ALA A 1 286 ? 118.654 118.650 131.830 1.00 93.41  ? 867 ALA A CA  1 
ATOM 1831 C C   . ALA A 1 286 ? 117.299 119.341 131.763 1.00 93.41  ? 867 ALA A C   1 
ATOM 1832 O O   . ALA A 1 286 ? 116.271 118.657 131.815 1.00 93.41  ? 867 ALA A O   1 
ATOM 1833 C CB  . ALA A 1 286 ? 119.177 118.694 133.265 1.00 93.41  ? 867 ALA A CB  1 
ATOM 1834 N N   . CYS A 1 287 ? 117.262 120.669 131.648 1.00 95.21  ? 868 CYS A N   1 
ATOM 1835 C CA  . CYS A 1 287 ? 115.997 121.392 131.678 1.00 95.21  ? 868 CYS A CA  1 
ATOM 1836 C C   . CYS A 1 287 ? 115.330 121.459 130.312 1.00 95.21  ? 868 CYS A C   1 
ATOM 1837 O O   . CYS A 1 287 ? 114.149 121.813 130.231 1.00 95.21  ? 868 CYS A O   1 
ATOM 1838 C CB  . CYS A 1 287 ? 116.184 122.804 132.238 1.00 95.21  ? 868 CYS A CB  1 
ATOM 1839 S SG  . CYS A 1 287 ? 117.181 123.911 131.237 1.00 95.21  ? 868 CYS A SG  1 
ATOM 1840 N N   . LEU A 1 288 ? 116.044 121.131 129.235 1.00 84.83  ? 869 LEU A N   1 
ATOM 1841 C CA  . LEU A 1 288 ? 115.367 120.892 127.967 1.00 84.83  ? 869 LEU A CA  1 
ATOM 1842 C C   . LEU A 1 288 ? 114.583 119.583 127.956 1.00 84.83  ? 869 LEU A C   1 
ATOM 1843 O O   . LEU A 1 288 ? 113.549 119.499 127.282 1.00 84.83  ? 869 LEU A O   1 
ATOM 1844 C CB  . LEU A 1 288 ? 116.379 120.946 126.812 1.00 84.83  ? 869 LEU A CB  1 
ATOM 1845 C CG  . LEU A 1 288 ? 115.897 120.731 125.374 1.00 84.83  ? 869 LEU A CG  1 
ATOM 1846 C CD1 . LEU A 1 288 ? 114.841 121.744 124.997 1.00 84.83  ? 869 LEU A CD1 1 
ATOM 1847 C CD2 . LEU A 1 288 ? 117.079 120.861 124.438 1.00 84.83  ? 869 LEU A CD2 1 
ATOM 1848 N N   . LEU A 1 289 ? 114.991 118.592 128.749 1.00 82.36  ? 870 LEU A N   1 
ATOM 1849 C CA  . LEU A 1 289 ? 114.303 117.309 128.820 1.00 82.36  ? 870 LEU A CA  1 
ATOM 1850 C C   . LEU A 1 289 ? 113.110 117.315 129.775 1.00 82.36  ? 870 LEU A C   1 
ATOM 1851 O O   . LEU A 1 289 ? 112.576 116.247 130.090 1.00 82.36  ? 870 LEU A O   1 
ATOM 1852 C CB  . LEU A 1 289 ? 115.280 116.203 129.216 1.00 82.36  ? 870 LEU A CB  1 
ATOM 1853 C CG  . LEU A 1 289 ? 116.178 115.692 128.091 1.00 82.36  ? 870 LEU A CG  1 
ATOM 1854 C CD1 . LEU A 1 289 ? 117.508 115.183 128.621 1.00 82.36  ? 870 LEU A CD1 1 
ATOM 1855 C CD2 . LEU A 1 289 ? 115.451 114.610 127.328 1.00 82.36  ? 870 LEU A CD2 1 
ATOM 1856 N N   . HIS A 1 290 ? 112.678 118.486 130.243 1.00 87.30  ? 871 HIS A N   1 
ATOM 1857 C CA  . HIS A 1 290 ? 111.483 118.584 131.069 1.00 87.30  ? 871 HIS A CA  1 
ATOM 1858 C C   . HIS A 1 290 ? 110.196 118.471 130.262 1.00 87.30  ? 871 HIS A C   1 
ATOM 1859 O O   . HIS A 1 290 ? 109.134 118.242 130.850 1.00 87.30  ? 871 HIS A O   1 
ATOM 1860 C CB  . HIS A 1 290 ? 111.483 119.903 131.851 1.00 87.30  ? 871 HIS A CB  1 
ATOM 1861 C CG  . HIS A 1 290 ? 110.657 119.867 133.099 1.00 87.30  ? 871 HIS A CG  1 
ATOM 1862 N ND1 . HIS A 1 290 ? 109.285 119.736 133.083 1.00 87.30  ? 871 HIS A ND1 1 
ATOM 1863 C CD2 . HIS A 1 290 ? 111.010 119.944 134.404 1.00 87.30  ? 871 HIS A CD2 1 
ATOM 1864 C CE1 . HIS A 1 290 ? 108.829 119.733 134.322 1.00 87.30  ? 871 HIS A CE1 1 
ATOM 1865 N NE2 . HIS A 1 290 ? 109.855 119.859 135.143 1.00 87.30  ? 871 HIS A NE2 1 
ATOM 1866 N N   . CYS A 1 291 ? 110.263 118.631 128.938 1.00 91.18  ? 872 CYS A N   1 
ATOM 1867 C CA  . CYS A 1 291 ? 109.071 118.471 128.111 1.00 91.18  ? 872 CYS A CA  1 
ATOM 1868 C C   . CYS A 1 291 ? 108.690 117.003 127.972 1.00 91.18  ? 872 CYS A C   1 
ATOM 1869 O O   . CYS A 1 291 ? 107.512 116.676 127.787 1.00 91.18  ? 872 CYS A O   1 
ATOM 1870 C CB  . CYS A 1 291 ? 109.301 119.096 126.735 1.00 91.18  ? 872 CYS A CB  1 
ATOM 1871 S SG  . CYS A 1 291 ? 109.441 120.897 126.735 1.00 91.18  ? 872 CYS A SG  1 
ATOM 1872 N N   . TYR A 1 292 ? 109.671 116.106 128.060 1.00 85.14  ? 873 TYR A N   1 
ATOM 1873 C CA  . TYR A 1 292 ? 109.434 114.685 127.846 1.00 85.14  ? 873 TYR A CA  1 
ATOM 1874 C C   . TYR A 1 292 ? 109.153 113.918 129.131 1.00 85.14  ? 873 TYR A C   1 
ATOM 1875 O O   . TYR A 1 292 ? 109.007 112.693 129.073 1.00 85.14  ? 873 TYR A O   1 
ATOM 1876 C CB  . TYR A 1 292 ? 110.636 114.053 127.138 1.00 85.14  ? 873 TYR A CB  1 
ATOM 1877 C CG  . TYR A 1 292 ? 110.978 114.678 125.804 1.00 85.14  ? 873 TYR A CG  1 
ATOM 1878 C CD1 . TYR A 1 292 ? 109.979 115.099 124.931 1.00 85.14  ? 873 TYR A CD1 1 
ATOM 1879 C CD2 . TYR A 1 292 ? 112.303 114.846 125.418 1.00 85.14  ? 873 TYR A CD2 1 
ATOM 1880 C CE1 . TYR A 1 292 ? 110.292 115.671 123.708 1.00 85.14  ? 873 TYR A CE1 1 
ATOM 1881 C CE2 . TYR A 1 292 ? 112.627 115.416 124.199 1.00 85.14  ? 873 TYR A CE2 1 
ATOM 1882 C CZ  . TYR A 1 292 ? 111.618 115.826 123.350 1.00 85.14  ? 873 TYR A CZ  1 
ATOM 1883 O OH  . TYR A 1 292 ? 111.938 116.393 122.139 1.00 85.14  ? 873 TYR A OH  1 
ATOM 1884 N N   . PHE A 1 293 ? 109.083 114.598 130.280 1.00 88.40  ? 874 PHE A N   1 
ATOM 1885 C CA  . PHE A 1 293 ? 108.867 113.899 131.545 1.00 88.40  ? 874 PHE A CA  1 
ATOM 1886 C C   . PHE A 1 293 ? 107.437 113.387 131.673 1.00 88.40  ? 874 PHE A C   1 
ATOM 1887 O O   . PHE A 1 293 ? 107.187 112.389 132.358 1.00 88.40  ? 874 PHE A O   1 
ATOM 1888 C CB  . PHE A 1 293 ? 109.214 114.810 132.723 1.00 88.40  ? 874 PHE A CB  1 
ATOM 1889 C CG  . PHE A 1 293 ? 110.693 114.967 132.966 1.00 88.40  ? 874 PHE A CG  1 
ATOM 1890 C CD1 . PHE A 1 293 ? 111.608 114.082 132.407 1.00 88.40  ? 874 PHE A CD1 1 
ATOM 1891 C CD2 . PHE A 1 293 ? 111.165 115.992 133.774 1.00 88.40  ? 874 PHE A CD2 1 
ATOM 1892 C CE1 . PHE A 1 293 ? 112.968 114.228 132.638 1.00 88.40  ? 874 PHE A CE1 1 
ATOM 1893 C CE2 . PHE A 1 293 ? 112.523 116.143 134.011 1.00 88.40  ? 874 PHE A CE2 1 
ATOM 1894 C CZ  . PHE A 1 293 ? 113.424 115.259 133.441 1.00 88.40  ? 874 PHE A CZ  1 
ATOM 1895 N N   . SER A 1 294 ? 106.482 114.056 131.025 1.00 91.26  ? 875 SER A N   1 
ATOM 1896 C CA  . SER A 1 294 ? 105.110 113.559 131.035 1.00 91.26  ? 875 SER A CA  1 
ATOM 1897 C C   . SER A 1 294 ? 104.910 112.443 130.017 1.00 91.26  ? 875 SER A C   1 
ATOM 1898 O O   . SER A 1 294 ? 103.906 111.724 130.075 1.00 91.26  ? 875 SER A O   1 
ATOM 1899 C CB  . SER A 1 294 ? 104.133 114.702 130.770 1.00 91.26  ? 875 SER A CB  1 
ATOM 1900 O OG  . SER A 1 294 ? 102.801 114.224 130.698 1.00 91.26  ? 875 SER A OG  1 
ATOM 1901 N N   . GLN A 1 295 ? 105.847 112.286 129.080 1.00 93.48  ? 876 GLN A N   1 
ATOM 1902 C CA  . GLN A 1 295 ? 105.737 111.255 128.054 1.00 93.48  ? 876 GLN A CA  1 
ATOM 1903 C C   . GLN A 1 295 ? 106.445 109.973 128.484 1.00 93.48  ? 876 GLN A C   1 
ATOM 1904 O O   . GLN A 1 295 ? 105.914 108.869 128.308 1.00 93.48  ? 876 GLN A O   1 
ATOM 1905 C CB  . GLN A 1 295 ? 106.309 111.784 126.734 1.00 93.48  ? 876 GLN A CB  1 
ATOM 1906 C CG  . GLN A 1 295 ? 106.440 110.753 125.627 1.00 93.48  ? 876 GLN A CG  1 
ATOM 1907 C CD  . GLN A 1 295 ? 106.639 111.390 124.268 1.00 93.48  ? 876 GLN A CD  1 
ATOM 1908 O OE1 . GLN A 1 295 ? 106.057 112.431 123.967 1.00 93.48  ? 876 GLN A OE1 1 
ATOM 1909 N NE2 . GLN A 1 295 ? 107.469 110.769 123.438 1.00 93.48  ? 876 GLN A NE2 1 
ATOM 1910 N N   . ILE A 1 296 ? 107.647 110.112 129.054 1.00 84.79  ? 877 ILE A N   1 
ATOM 1911 C CA  . ILE A 1 296 ? 108.435 108.960 129.495 1.00 84.79  ? 877 ILE A CA  1 
ATOM 1912 C C   . ILE A 1 296 ? 107.775 108.275 130.686 1.00 84.79  ? 877 ILE A C   1 
ATOM 1913 O O   . ILE A 1 296 ? 107.675 107.042 130.732 1.00 84.79  ? 877 ILE A O   1 
ATOM 1914 C CB  . ILE A 1 296 ? 109.879 109.404 129.808 1.00 84.79  ? 877 ILE A CB  1 
ATOM 1915 C CG1 . ILE A 1 296 ? 110.597 109.793 128.520 1.00 84.79  ? 877 ILE A CG1 1 
ATOM 1916 C CG2 . ILE A 1 296 ? 110.675 108.313 130.519 1.00 84.79  ? 877 ILE A CG2 1 
ATOM 1917 C CD1 . ILE A 1 296 ? 110.762 108.643 127.565 1.00 84.79  ? 877 ILE A CD1 1 
ATOM 1918 N N   . ARG A 1 297 ? 107.262 109.058 131.639 1.00 90.60  ? 878 ARG A N   1 
ATOM 1919 C CA  . ARG A 1 297 ? 106.648 108.473 132.827 1.00 90.60  ? 878 ARG A CA  1 
ATOM 1920 C C   . ARG A 1 297 ? 105.277 107.864 132.550 1.00 90.60  ? 878 ARG A C   1 
ATOM 1921 O O   . ARG A 1 297 ? 104.760 107.129 133.399 1.00 90.60  ? 878 ARG A O   1 
ATOM 1922 C CB  . ARG A 1 297 ? 106.546 109.518 133.938 1.00 90.60  ? 878 ARG A CB  1 
ATOM 1923 C CG  . ARG A 1 297 ? 107.680 109.424 134.943 1.00 90.60  ? 878 ARG A CG  1 
ATOM 1924 C CD  . ARG A 1 297 ? 107.577 110.465 136.043 1.00 90.60  ? 878 ARG A CD  1 
ATOM 1925 N NE  . ARG A 1 297 ? 107.848 111.825 135.597 1.00 90.60  ? 878 ARG A NE  1 
ATOM 1926 C CZ  . ARG A 1 297 ? 108.039 112.848 136.418 1.00 90.60  ? 878 ARG A CZ  1 
ATOM 1927 N NH1 . ARG A 1 297 ? 107.994 112.697 137.732 1.00 90.60  ? 878 ARG A NH1 1 
ATOM 1928 N NH2 . ARG A 1 297 ? 108.283 114.053 135.911 1.00 90.60  ? 878 ARG A NH2 1 
ATOM 1929 N N   . LYS A 1 298 ? 104.676 108.148 131.393 1.00 96.54  ? 879 LYS A N   1 
ATOM 1930 C CA  . LYS A 1 298 ? 103.478 107.427 130.977 1.00 96.54  ? 879 LYS A CA  1 
ATOM 1931 C C   . LYS A 1 298 ? 103.821 106.214 130.119 1.00 96.54  ? 879 LYS A C   1 
ATOM 1932 O O   . LYS A 1 298 ? 103.203 105.152 130.267 1.00 96.54  ? 879 LYS A O   1 
ATOM 1933 C CB  . LYS A 1 298 ? 102.524 108.376 130.247 1.00 96.54  ? 879 LYS A CB  1 
ATOM 1934 C CG  . LYS A 1 298 ? 101.246 107.723 129.743 1.00 96.54  ? 879 LYS A CG  1 
ATOM 1935 C CD  . LYS A 1 298 ? 100.424 107.145 130.879 1.00 96.54  ? 879 LYS A CD  1 
ATOM 1936 C CE  . LYS A 1 298 ? 99.815  108.209 131.758 1.00 96.54  ? 879 LYS A CE  1 
ATOM 1937 N NZ  . LYS A 1 298 ? 98.972  107.566 132.800 1.00 96.54  ? 879 LYS A NZ  1 
ATOM 1938 N N   . ASP A 1 299 ? 104.831 106.330 129.252 1.00 95.47  ? 880 ASP A N   1 
ATOM 1939 C CA  . ASP A 1 299 ? 105.194 105.206 128.391 1.00 95.47  ? 880 ASP A CA  1 
ATOM 1940 C C   . ASP A 1 299 ? 105.976 104.140 129.153 1.00 95.47  ? 880 ASP A C   1 
ATOM 1941 O O   . ASP A 1 299 ? 106.143 103.017 128.665 1.00 95.47  ? 880 ASP A O   1 
ATOM 1942 C CB  . ASP A 1 299 ? 105.995 105.702 127.188 1.00 95.47  ? 880 ASP A CB  1 
ATOM 1943 C CG  . ASP A 1 299 ? 105.155 106.518 126.224 1.00 95.47  ? 880 ASP A CG  1 
ATOM 1944 O OD1 . ASP A 1 299 ? 104.162 107.132 126.669 1.00 95.47  ? 880 ASP A OD1 1 
ATOM 1945 O OD2 . ASP A 1 299 ? 105.488 106.547 125.020 1.00 95.47  ? 880 ASP A OD2 1 
ATOM 1946 N N   . ALA A 1 300 ? 106.467 104.470 130.345 1.00 88.34  ? 881 ALA A N   1 
ATOM 1947 C CA  . ALA A 1 300 ? 107.189 103.528 131.185 1.00 88.34  ? 881 ALA A CA  1 
ATOM 1948 C C   . ALA A 1 300 ? 106.286 102.786 132.160 1.00 88.34  ? 881 ALA A C   1 
ATOM 1949 O O   . ALA A 1 300 ? 106.478 101.585 132.369 1.00 88.34  ? 881 ALA A O   1 
ATOM 1950 C CB  . ALA A 1 300 ? 108.285 104.259 131.959 1.00 88.34  ? 881 ALA A CB  1 
ATOM 1951 N N   . LEU A 1 301 ? 105.313 103.469 132.759 1.00 86.85  ? 882 LEU A N   1 
ATOM 1952 C CA  . LEU A 1 301 ? 104.411 102.854 133.722 1.00 86.85  ? 882 LEU A CA  1 
ATOM 1953 C C   . LEU A 1 301 ? 103.362 101.980 133.048 1.00 86.85  ? 882 LEU A C   1 
ATOM 1954 O O   . LEU A 1 301 ? 102.779 101.113 133.707 1.00 86.85  ? 882 LEU A O   1 
ATOM 1955 C CB  . LEU A 1 301 ? 103.756 103.951 134.585 1.00 86.85  ? 882 LEU A CB  1 
ATOM 1956 C CG  . LEU A 1 301 ? 102.871 103.728 135.824 1.00 86.85  ? 882 LEU A CG  1 
ATOM 1957 C CD1 . LEU A 1 301 ? 102.998 104.941 136.719 1.00 86.85  ? 882 LEU A CD1 1 
ATOM 1958 C CD2 . LEU A 1 301 ? 101.395 103.532 135.507 1.00 86.85  ? 882 LEU A CD2 1 
ATOM 1959 N N   . ARG A 1 302 ? 103.129 102.173 131.748 1.00 88.45  ? 883 ARG A N   1 
ATOM 1960 C CA  . ARG A 1 302 ? 102.197 101.335 131.000 1.00 88.45  ? 883 ARG A CA  1 
ATOM 1961 C C   . ARG A 1 302 ? 102.738 99.918  130.839 1.00 88.45  ? 883 ARG A C   1 
ATOM 1962 O O   . ARG A 1 302 ? 101.981 98.943  130.887 1.00 88.45  ? 883 ARG A O   1 
ATOM 1963 C CB  . ARG A 1 302 ? 101.915 101.966 129.635 1.00 88.45  ? 883 ARG A CB  1 
ATOM 1964 C CG  . ARG A 1 302 ? 100.713 101.387 128.918 1.00 88.45  ? 883 ARG A CG  1 
ATOM 1965 C CD  . ARG A 1 302 ? 100.658 101.841 127.469 1.00 88.45  ? 883 ARG A CD  1 
ATOM 1966 N NE  . ARG A 1 302 ? 100.662 103.292 127.336 1.00 88.45  ? 883 ARG A NE  1 
ATOM 1967 C CZ  . ARG A 1 302 ? 101.602 103.983 126.705 1.00 88.45  ? 883 ARG A CZ  1 
ATOM 1968 N NH1 . ARG A 1 302 ? 102.633 103.383 126.132 1.00 88.45  ? 883 ARG A NH1 1 
ATOM 1969 N NH2 . ARG A 1 302 ? 101.505 105.307 126.645 1.00 88.45  ? 883 ARG A NH2 1 
ATOM 1970 N N   . ALA A 1 303 ? 104.053 99.789  130.646 1.00 77.91  ? 884 ALA A N   1 
ATOM 1971 C CA  . ALA A 1 303 ? 104.664 98.467  130.577 1.00 77.91  ? 884 ALA A CA  1 
ATOM 1972 C C   . ALA A 1 303 ? 104.756 97.829  131.957 1.00 77.91  ? 884 ALA A C   1 
ATOM 1973 O O   . ALA A 1 303 ? 104.679 96.601  132.089 1.00 77.91  ? 884 ALA A O   1 
ATOM 1974 C CB  . ALA A 1 303 ? 106.048 98.561  129.935 1.00 77.91  ? 884 ALA A CB  1 
ATOM 1975 N N   . LEU A 1 304 ? 104.907 98.648  132.999 1.00 80.53  ? 885 LEU A N   1 
ATOM 1976 C CA  . LEU A 1 304 ? 105.038 98.171  134.370 1.00 80.53  ? 885 LEU A CA  1 
ATOM 1977 C C   . LEU A 1 304 ? 103.695 97.889  135.033 1.00 80.53  ? 885 LEU A C   1 
ATOM 1978 O O   . LEU A 1 304 ? 103.669 97.474  136.198 1.00 80.53  ? 885 LEU A O   1 
ATOM 1979 C CB  . LEU A 1 304 ? 105.830 99.181  135.205 1.00 80.53  ? 885 LEU A CB  1 
ATOM 1980 C CG  . LEU A 1 304 ? 107.317 99.338  134.879 1.00 80.53  ? 885 LEU A CG  1 
ATOM 1981 C CD1 . LEU A 1 304 ? 107.979 100.297 135.855 1.00 80.53  ? 885 LEU A CD1 1 
ATOM 1982 C CD2 . LEU A 1 304 ? 108.024 97.991  134.887 1.00 80.53  ? 885 LEU A CD2 1 
ATOM 1983 N N   . ASN A 1 305 ? 102.582 98.114  134.326 1.00 89.40  ? 886 ASN A N   1 
ATOM 1984 C CA  . ASN A 1 305 ? 101.249 97.768  134.819 1.00 89.40  ? 886 ASN A CA  1 
ATOM 1985 C C   . ASN A 1 305 ? 100.704 96.707  133.855 1.00 89.40  ? 886 ASN A C   1 
ATOM 1986 O O   . ASN A 1 305 ? 99.517  96.377  133.822 1.00 89.40  ? 886 ASN A O   1 
ATOM 1987 C CB  . ASN A 1 305 ? 100.338 98.993  134.909 1.00 89.40  ? 886 ASN A CB  1 
ATOM 1988 C CG  . ASN A 1 305 ? 99.108  98.750  135.763 1.00 89.40  ? 886 ASN A CG  1 
ATOM 1989 O OD1 . ASN A 1 305 ? 99.135  98.920  136.981 1.00 89.40  ? 886 ASN A OD1 1 
ATOM 1990 N ND2 . ASN A 1 305 ? 98.019  98.347  135.122 1.00 89.40  ? 886 ASN A ND2 1 
ATOM 1991 N N   . PHE A 1 306 ? 101.609 96.150  133.054 1.00 83.97  ? 887 PHE A N   1 
ATOM 1992 C CA  . PHE A 1 306 ? 101.251 95.117  132.092 1.00 83.97  ? 887 PHE A CA  1 
ATOM 1993 C C   . PHE A 1 306 ? 102.099 93.875  132.324 1.00 83.97  ? 887 PHE A C   1 
ATOM 1994 O O   . PHE A 1 306 ? 101.627 92.747  132.153 1.00 83.97  ? 887 PHE A O   1 
ATOM 1995 C CB  . PHE A 1 306 ? 101.450 95.621  130.661 1.00 83.97  ? 887 PHE A CB  1 
ATOM 1996 C CG  . PHE A 1 306 ? 101.075 94.619  129.606 1.00 83.97  ? 887 PHE A CG  1 
ATOM 1997 C CD1 . PHE A 1 306 ? 99.749  94.268  129.407 1.00 83.97  ? 887 PHE A CD1 1 
ATOM 1998 C CD2 . PHE A 1 306 ? 102.052 94.003  128.839 1.00 83.97  ? 887 PHE A CD2 1 
ATOM 1999 C CE1 . PHE A 1 306 ? 99.399  93.341  128.434 1.00 83.97  ? 887 PHE A CE1 1 
ATOM 2000 C CE2 . PHE A 1 306 ? 101.712 93.070  127.870 1.00 83.97  ? 887 PHE A CE2 1 
ATOM 2001 C CZ  . PHE A 1 306 ? 100.383 92.739  127.670 1.00 83.97  ? 887 PHE A CZ  1 
ATOM 2002 N N   . ALA A 1 307 ? 103.355 94.082  132.720 1.00 75.26  ? 888 ALA A N   1 
ATOM 2003 C CA  . ALA A 1 307 ? 104.312 92.987  132.799 1.00 75.26  ? 888 ALA A CA  1 
ATOM 2004 C C   . ALA A 1 307 ? 104.356 92.323  134.167 1.00 75.26  ? 888 ALA A C   1 
ATOM 2005 O O   . ALA A 1 307 ? 105.207 91.454  134.379 1.00 75.26  ? 888 ALA A O   1 
ATOM 2006 C CB  . ALA A 1 307 ? 105.709 93.493  132.437 1.00 75.26  ? 888 ALA A CB  1 
ATOM 2007 N N   . TYR A 1 308 ? 103.485 92.707  135.101 1.00 80.64  ? 889 TYR A N   1 
ATOM 2008 C CA  . TYR A 1 308 ? 103.560 92.196  136.465 1.00 80.64  ? 889 TYR A CA  1 
ATOM 2009 C C   . TYR A 1 308 ? 102.297 91.450  136.887 1.00 80.64  ? 889 TYR A C   1 
ATOM 2010 O O   . TYR A 1 308 ? 102.230 90.946  138.012 1.00 80.64  ? 889 TYR A O   1 
ATOM 2011 C CB  . TYR A 1 308 ? 103.852 93.335  137.445 1.00 80.64  ? 889 TYR A CB  1 
ATOM 2012 C CG  . TYR A 1 308 ? 105.321 93.696  137.590 1.00 80.64  ? 889 TYR A CG  1 
ATOM 2013 C CD1 . TYR A 1 308 ? 106.051 94.193  136.513 1.00 80.64  ? 889 TYR A CD1 1 
ATOM 2014 C CD2 . TYR A 1 308 ? 105.976 93.536  138.807 1.00 80.64  ? 889 TYR A CD2 1 
ATOM 2015 C CE1 . TYR A 1 308 ? 107.391 94.523  136.643 1.00 80.64  ? 889 TYR A CE1 1 
ATOM 2016 C CE2 . TYR A 1 308 ? 107.317 93.863  138.949 1.00 80.64  ? 889 TYR A CE2 1 
ATOM 2017 C CZ  . TYR A 1 308 ? 108.016 94.355  137.862 1.00 80.64  ? 889 TYR A CZ  1 
ATOM 2018 O OH  . TYR A 1 308 ? 109.346 94.681  137.995 1.00 80.64  ? 889 TYR A OH  1 
ATOM 2019 N N   . THR A 1 309 ? 101.303 91.348  136.007 1.00 85.87  ? 890 THR A N   1 
ATOM 2020 C CA  . THR A 1 309 ? 100.027 90.726  136.332 1.00 85.87  ? 890 THR A CA  1 
ATOM 2021 C C   . THR A 1 309 ? 99.936  89.354  135.680 1.00 85.87  ? 890 THR A C   1 
ATOM 2022 O O   . THR A 1 309 ? 100.677 89.049  134.742 1.00 85.87  ? 890 THR A O   1 
ATOM 2023 C CB  . THR A 1 309 ? 98.858  91.585  135.862 1.00 85.87  ? 890 THR A CB  1 
ATOM 2024 O OG1 . THR A 1 309 ? 98.925  91.723  134.439 1.00 85.87  ? 890 THR A OG1 1 
ATOM 2025 C CG2 . THR A 1 309 ? 98.924  92.961  136.500 1.00 85.87  ? 890 THR A CG2 1 
ATOM 2026 N N   . VAL A 1 310 ? 99.018  88.522  136.181 1.00 104.20 ? 891 VAL A N   1 
ATOM 2027 C CA  . VAL A 1 310 ? 98.899  87.174  135.628 1.00 104.20 ? 891 VAL A CA  1 
ATOM 2028 C C   . VAL A 1 310 ? 97.959  87.145  134.412 1.00 104.20 ? 891 VAL A C   1 
ATOM 2029 O O   . VAL A 1 310 ? 98.382  86.748  133.319 1.00 104.20 ? 891 VAL A O   1 
ATOM 2030 C CB  . VAL A 1 310 ? 98.577  86.139  136.741 1.00 104.20 ? 891 VAL A CB  1 
ATOM 2031 C CG1 . VAL A 1 310 ? 97.268  86.373  137.529 1.00 104.20 ? 891 VAL A CG1 1 
ATOM 2032 C CG2 . VAL A 1 310 ? 98.591  84.729  136.160 1.00 104.20 ? 891 VAL A CG2 1 
ATOM 2033 N N   . SER A 1 311 ? 96.689  87.550  134.552 1.00 104.60 ? 892 SER A N   1 
ATOM 2034 C CA  . SER A 1 311 ? 95.901  87.766  133.344 1.00 104.60 ? 892 SER A CA  1 
ATOM 2035 C C   . SER A 1 311 ? 95.333  89.177  133.240 1.00 104.60 ? 892 SER A C   1 
ATOM 2036 O O   . SER A 1 311 ? 95.786  89.966  132.406 1.00 104.60 ? 892 SER A O   1 
ATOM 2037 C CB  . SER A 1 311 ? 94.762  86.747  133.278 1.00 104.60 ? 892 SER A CB  1 
ATOM 2038 O OG  . SER A 1 311 ? 93.865  86.915  134.363 1.00 104.60 ? 892 SER A OG  1 
ATOM 2039 N N   . THR A 1 312 ? 94.348  89.506  134.082 1.00 105.73 ? 893 THR A N   1 
ATOM 2040 C CA  . THR A 1 312 ? 93.863  90.878  134.212 1.00 105.73 ? 893 THR A CA  1 
ATOM 2041 C C   . THR A 1 312 ? 93.302  91.167  135.600 1.00 105.73 ? 893 THR A C   1 
ATOM 2042 O O   . THR A 1 312 ? 92.856  92.287  135.866 1.00 105.73 ? 893 THR A O   1 
ATOM 2043 C CB  . THR A 1 312 ? 92.785  91.174  133.164 1.00 105.73 ? 893 THR A CB  1 
ATOM 2044 O OG1 . THR A 1 312 ? 92.354  92.535  133.293 1.00 105.73 ? 893 THR A OG1 1 
ATOM 2045 C CG2 . THR A 1 312 ? 91.592  90.252  133.354 1.00 105.73 ? 893 THR A CG2 1 
ATOM 2046 N N   . GLN A 1 313 ? 93.313  90.175  136.492 1.00 111.66 ? 894 GLN A N   1 
ATOM 2047 C CA  . GLN A 1 313 ? 92.435  90.208  137.653 1.00 111.66 ? 894 GLN A CA  1 
ATOM 2048 C C   . GLN A 1 313 ? 93.125  89.994  138.991 1.00 111.66 ? 894 GLN A C   1 
ATOM 2049 O O   . GLN A 1 313 ? 92.429  89.828  139.999 1.00 111.66 ? 894 GLN A O   1 
ATOM 2050 C CB  . GLN A 1 313 ? 91.321  89.159  137.506 1.00 111.66 ? 894 GLN A CB  1 
ATOM 2051 N N   . ARG A 1 314 ? 94.451  89.993  139.042 1.00 112.36 ? 895 ARG A N   1 
ATOM 2052 C CA  . ARG A 1 314 ? 95.161  89.846  140.306 1.00 112.36 ? 895 ARG A CA  1 
ATOM 2053 C C   . ARG A 1 314 ? 95.814  91.186  140.634 1.00 112.36 ? 895 ARG A C   1 
ATOM 2054 O O   . ARG A 1 314 ? 95.686  92.176  139.902 1.00 112.36 ? 895 ARG A O   1 
ATOM 2055 C CB  . ARG A 1 314 ? 96.173  88.697  140.238 1.00 112.36 ? 895 ARG A CB  1 
ATOM 2056 N N   . SER A 1 315 ? 96.527  91.231  141.754 1.00 108.87 ? 896 SER A N   1 
ATOM 2057 C CA  . SER A 1 315 ? 97.194  92.444  142.192 1.00 108.87 ? 896 SER A CA  1 
ATOM 2058 C C   . SER A 1 315 ? 98.643  92.128  142.523 1.00 108.87 ? 896 SER A C   1 
ATOM 2059 O O   . SER A 1 315 ? 98.934  91.233  143.320 1.00 108.87 ? 896 SER A O   1 
ATOM 2060 C CB  . SER A 1 315 ? 96.496  93.059  143.409 1.00 108.87 ? 896 SER A CB  1 
ATOM 2061 O OG  . SER A 1 315 ? 95.188  93.492  143.078 1.00 108.87 ? 896 SER A OG  1 
ATOM 2062 N N   . THR A 1 316 ? 99.548  92.875  141.903 1.00 104.67 ? 897 THR A N   1 
ATOM 2063 C CA  . THR A 1 316 ? 100.976 92.743  142.151 1.00 104.67 ? 897 THR A CA  1 
ATOM 2064 C C   . THR A 1 316 ? 101.415 93.861  143.090 1.00 104.67 ? 897 THR A C   1 
ATOM 2065 O O   . THR A 1 316 ? 101.425 95.042  142.735 1.00 104.67 ? 897 THR A O   1 
ATOM 2066 C CB  . THR A 1 316 ? 101.753 92.772  140.841 1.00 104.67 ? 897 THR A CB  1 
ATOM 2067 O OG1 . THR A 1 316 ? 101.324 91.688  140.012 1.00 104.67 ? 897 THR A OG1 1 
ATOM 2068 C CG2 . THR A 1 316 ? 103.242 92.634  141.112 1.00 104.67 ? 897 THR A CG2 1 
ATOM 2069 N N   . ILE A 1 317 ? 101.771 93.469  144.311 1.00 107.52 ? 898 ILE A N   1 
ATOM 2070 C CA  . ILE A 1 317 ? 102.168 94.411  145.350 1.00 107.52 ? 898 ILE A CA  1 
ATOM 2071 C C   . ILE A 1 317 ? 103.565 94.916  145.013 1.00 107.52 ? 898 ILE A C   1 
ATOM 2072 O O   . ILE A 1 317 ? 104.556 94.186  145.137 1.00 107.52 ? 898 ILE A O   1 
ATOM 2073 C CB  . ILE A 1 317 ? 102.110 93.778  146.759 1.00 107.52 ? 898 ILE A CB  1 
ATOM 2074 C CG1 . ILE A 1 317 ? 100.674 93.394  147.152 1.00 107.52 ? 898 ILE A CG1 1 
ATOM 2075 C CG2 . ILE A 1 317 ? 102.665 94.729  147.806 1.00 107.52 ? 898 ILE A CG2 1 
ATOM 2076 C CD1 . ILE A 1 317 ? 100.279 91.938  146.890 1.00 107.52 ? 898 ILE A CD1 1 
ATOM 2077 N N   . PHE A 1 318 ? 103.643 96.155  144.549 1.00 103.35 ? 899 PHE A N   1 
ATOM 2078 C CA  . PHE A 1 318 ? 104.874 96.782  144.105 1.00 103.35 ? 899 PHE A CA  1 
ATOM 2079 C C   . PHE A 1 318 ? 105.326 97.829  145.112 1.00 103.35 ? 899 PHE A C   1 
ATOM 2080 O O   . PHE A 1 318 ? 104.643 98.835  145.328 1.00 103.35 ? 899 PHE A O   1 
ATOM 2081 C CB  . PHE A 1 318 ? 104.669 97.427  142.731 1.00 103.35 ? 899 PHE A CB  1 
ATOM 2082 C CG  . PHE A 1 318 ? 105.942 97.837  142.058 1.00 103.35 ? 899 PHE A CG  1 
ATOM 2083 C CD1 . PHE A 1 318 ? 106.922 96.896  141.777 1.00 103.35 ? 899 PHE A CD1 1 
ATOM 2084 C CD2 . PHE A 1 318 ? 106.155 99.158  141.693 1.00 103.35 ? 899 PHE A CD2 1 
ATOM 2085 C CE1 . PHE A 1 318 ? 108.100 97.265  141.152 1.00 103.35 ? 899 PHE A CE1 1 
ATOM 2086 C CE2 . PHE A 1 318 ? 107.329 99.537  141.065 1.00 103.35 ? 899 PHE A CE2 1 
ATOM 2087 C CZ  . PHE A 1 318 ? 108.302 98.588  140.795 1.00 103.35 ? 899 PHE A CZ  1 
ATOM 2088 N N   . PRO A 1 319 ? 106.490 97.623  145.749 1.00 114.92 ? 900 PRO A N   1 
ATOM 2089 C CA  . PRO A 1 319 ? 106.865 98.450  146.906 1.00 114.92 ? 900 PRO A CA  1 
ATOM 2090 C C   . PRO A 1 319 ? 107.324 99.856  146.554 1.00 114.92 ? 900 PRO A C   1 
ATOM 2091 O O   . PRO A 1 319 ? 107.705 100.136 145.413 1.00 114.92 ? 900 PRO A O   1 
ATOM 2092 C CB  . PRO A 1 319 ? 108.001 97.645  147.545 1.00 114.92 ? 900 PRO A CB  1 
ATOM 2093 C CG  . PRO A 1 319 ? 108.644 96.957  146.392 1.00 114.92 ? 900 PRO A CG  1 
ATOM 2094 C CD  . PRO A 1 319 ? 107.544 96.653  145.402 1.00 114.92 ? 900 PRO A CD  1 
ATOM 2095 N N   . LEU A 1 320 ? 107.293 100.746 147.545 1.00 114.20 ? 901 LEU A N   1 
ATOM 2096 C CA  . LEU A 1 320 ? 107.756 102.112 147.348 1.00 114.20 ? 901 LEU A CA  1 
ATOM 2097 C C   . LEU A 1 320 ? 109.277 102.179 147.424 1.00 114.20 ? 901 LEU A C   1 
ATOM 2098 O O   . LEU A 1 320 ? 109.951 101.173 147.670 1.00 114.20 ? 901 LEU A O   1 
ATOM 2099 C CB  . LEU A 1 320 ? 107.134 103.045 148.385 1.00 114.20 ? 901 LEU A CB  1 
ATOM 2100 C CG  . LEU A 1 320 ? 105.772 103.628 148.006 1.00 114.20 ? 901 LEU A CG  1 
ATOM 2101 C CD1 . LEU A 1 320 ? 105.092 104.247 149.217 1.00 114.20 ? 901 LEU A CD1 1 
ATOM 2102 C CD2 . LEU A 1 320 ? 105.925 104.650 146.889 1.00 114.20 ? 901 LEU A CD2 1 
ATOM 2103 N N   . ASP A 1 321 ? 109.804 103.379 147.118 1.00 114.22 ? 902 ASP A N   1 
ATOM 2104 C CA  . ASP A 1 321 ? 111.213 103.801 147.072 1.00 114.22 ? 902 ASP A CA  1 
ATOM 2105 C C   . ASP A 1 321 ? 111.987 103.140 145.926 1.00 114.22 ? 902 ASP A C   1 
ATOM 2106 O O   . ASP A 1 321 ? 113.201 103.328 145.796 1.00 114.22 ? 902 ASP A O   1 
ATOM 2107 C CB  . ASP A 1 321 ? 111.920 103.571 148.422 1.00 114.22 ? 902 ASP A CB  1 
ATOM 2108 C CG  . ASP A 1 321 ? 113.060 104.547 148.668 1.00 114.22 ? 902 ASP A CG  1 
ATOM 2109 O OD1 . ASP A 1 321 ? 113.294 105.429 147.815 1.00 114.22 ? 902 ASP A OD1 1 
ATOM 2110 O OD2 . ASP A 1 321 ? 113.726 104.427 149.718 1.00 114.22 ? 902 ASP A OD2 1 
ATOM 2111 N N   . GLY A 1 322 ? 111.300 102.370 145.082 1.00 105.52 ? 903 GLY A N   1 
ATOM 2112 C CA  . GLY A 1 322 ? 111.894 101.922 143.840 1.00 105.52 ? 903 GLY A CA  1 
ATOM 2113 C C   . GLY A 1 322 ? 111.325 102.653 142.645 1.00 105.52 ? 903 GLY A C   1 
ATOM 2114 O O   . GLY A 1 322 ? 112.024 102.864 141.651 1.00 105.52 ? 903 GLY A O   1 
ATOM 2115 N N   . VAL A 1 323 ? 110.051 103.052 142.727 1.00 98.74  ? 904 VAL A N   1 
ATOM 2116 C CA  . VAL A 1 323 ? 109.426 103.837 141.666 1.00 98.74  ? 904 VAL A CA  1 
ATOM 2117 C C   . VAL A 1 323 ? 110.040 105.237 141.601 1.00 98.74  ? 904 VAL A C   1 
ATOM 2118 O O   . VAL A 1 323 ? 110.258 105.785 140.513 1.00 98.74  ? 904 VAL A O   1 
ATOM 2119 C CB  . VAL A 1 323 ? 107.887 103.842 141.837 1.00 98.74  ? 904 VAL A CB  1 
ATOM 2120 C CG1 . VAL A 1 323 ? 107.414 104.484 143.153 1.00 98.74  ? 904 VAL A CG1 1 
ATOM 2121 C CG2 . VAL A 1 323 ? 107.202 104.500 140.650 1.00 98.74  ? 904 VAL A CG2 1 
ATOM 2122 N N   . VAL A 1 324 ? 110.422 105.795 142.758 1.00 98.05  ? 905 VAL A N   1 
ATOM 2123 C CA  . VAL A 1 324 ? 111.147 107.061 142.789 1.00 98.05  ? 905 VAL A CA  1 
ATOM 2124 C C   . VAL A 1 324 ? 112.627 106.878 142.489 1.00 98.05  ? 905 VAL A C   1 
ATOM 2125 O O   . VAL A 1 324 ? 113.341 107.876 142.307 1.00 98.05  ? 905 VAL A O   1 
ATOM 2126 C CB  . VAL A 1 324 ? 110.970 107.775 144.145 1.00 98.05  ? 905 VAL A CB  1 
ATOM 2127 C CG1 . VAL A 1 324 ? 109.498 107.849 144.514 1.00 98.05  ? 905 VAL A CG1 1 
ATOM 2128 C CG2 . VAL A 1 324 ? 111.761 107.072 145.233 1.00 98.05  ? 905 VAL A CG2 1 
ATOM 2129 N N   . ARG A 1 325 ? 113.111 105.637 142.428 1.00 97.82  ? 906 ARG A N   1 
ATOM 2130 C CA  . ARG A 1 325 ? 114.490 105.356 142.057 1.00 97.82  ? 906 ARG A CA  1 
ATOM 2131 C C   . ARG A 1 325 ? 114.647 105.217 140.546 1.00 97.82  ? 906 ARG A C   1 
ATOM 2132 O O   . ARG A 1 325 ? 115.588 105.769 139.969 1.00 97.82  ? 906 ARG A O   1 
ATOM 2133 C CB  . ARG A 1 325 ? 114.977 104.091 142.768 1.00 97.82  ? 906 ARG A CB  1 
ATOM 2134 C CG  . ARG A 1 325 ? 116.459 103.815 142.595 1.00 97.82  ? 906 ARG A CG  1 
ATOM 2135 C CD  . ARG A 1 325 ? 116.882 102.598 143.396 1.00 97.82  ? 906 ARG A CD  1 
ATOM 2136 N NE  . ARG A 1 325 ? 116.240 101.380 142.920 1.00 97.82  ? 906 ARG A NE  1 
ATOM 2137 C CZ  . ARG A 1 325 ? 115.933 100.346 143.692 1.00 97.82  ? 906 ARG A CZ  1 
ATOM 2138 N NH1 . ARG A 1 325 ? 116.192 100.351 144.989 1.00 97.82  ? 906 ARG A NH1 1 
ATOM 2139 N NH2 . ARG A 1 325 ? 115.351 99.281  143.149 1.00 97.82  ? 906 ARG A NH2 1 
ATOM 2140 N N   . MET A 1 326 ? 113.742 104.486 139.890 1.00 99.13  ? 907 MET A N   1 
ATOM 2141 C CA  . MET A 1 326 ? 113.785 104.427 138.435 1.00 99.13  ? 907 MET A CA  1 
ATOM 2142 C C   . MET A 1 326 ? 113.207 105.707 137.846 1.00 99.13  ? 907 MET A C   1 
ATOM 2143 O O   . MET A 1 326 ? 113.920 106.447 137.163 1.00 99.13  ? 907 MET A O   1 
ATOM 2144 C CB  . MET A 1 326 ? 113.044 103.207 137.877 1.00 99.13  ? 907 MET A CB  1 
ATOM 2145 C CG  . MET A 1 326 ? 113.192 101.914 138.663 1.00 99.13  ? 907 MET A CG  1 
ATOM 2146 S SD  . MET A 1 326 ? 111.966 100.685 138.154 1.00 99.13  ? 907 MET A SD  1 
ATOM 2147 C CE  . MET A 1 326 ? 110.624 100.987 139.296 1.00 99.13  ? 907 MET A CE  1 
ATOM 2148 N N   . LEU A 1 327 ? 111.929 105.986 138.104 1.00 97.19  ? 908 LEU A N   1 
ATOM 2149 C CA  . LEU A 1 327 ? 111.346 107.230 137.620 1.00 97.19  ? 908 LEU A CA  1 
ATOM 2150 C C   . LEU A 1 327 ? 111.772 108.382 138.520 1.00 97.19  ? 908 LEU A C   1 
ATOM 2151 O O   . LEU A 1 327 ? 111.679 108.293 139.747 1.00 97.19  ? 908 LEU A O   1 
ATOM 2152 C CB  . LEU A 1 327 ? 109.824 107.125 137.556 1.00 97.19  ? 908 LEU A CB  1 
ATOM 2153 C CG  . LEU A 1 327 ? 109.256 105.915 136.816 1.00 97.19  ? 908 LEU A CG  1 
ATOM 2154 C CD1 . LEU A 1 327 ? 107.793 105.712 137.152 1.00 97.19  ? 908 LEU A CD1 1 
ATOM 2155 C CD2 . LEU A 1 327 ? 109.433 106.093 135.323 1.00 97.19  ? 908 LEU A CD2 1 
ATOM 2156 N N   . LEU A 1 328 ? 112.243 109.467 137.910 1.00 92.76  ? 909 LEU A N   1 
ATOM 2157 C CA  . LEU A 1 328 ? 112.828 110.557 138.678 1.00 92.76  ? 909 LEU A CA  1 
ATOM 2158 C C   . LEU A 1 328 ? 111.745 111.475 139.234 1.00 92.76  ? 909 LEU A C   1 
ATOM 2159 O O   . LEU A 1 328 ? 111.299 112.406 138.556 1.00 92.76  ? 909 LEU A O   1 
ATOM 2160 C CB  . LEU A 1 328 ? 113.817 111.343 137.815 1.00 92.76  ? 909 LEU A CB  1 
ATOM 2161 C CG  . LEU A 1 328 ? 114.635 112.430 138.513 1.00 92.76  ? 909 LEU A CG  1 
ATOM 2162 C CD1 . LEU A 1 328 ? 115.520 111.815 139.583 1.00 92.76  ? 909 LEU A CD1 1 
ATOM 2163 C CD2 . LEU A 1 328 ? 115.465 113.204 137.503 1.00 92.76  ? 909 LEU A CD2 1 
ATOM 2164 N N   . PHE A 1 329 ? 111.301 111.203 140.458 1.00 101.46 ? 910 PHE A N   1 
ATOM 2165 C CA  . PHE A 1 329 ? 110.371 112.082 141.153 1.00 101.46 ? 910 PHE A CA  1 
ATOM 2166 C C   . PHE A 1 329 ? 111.135 112.964 142.137 1.00 101.46 ? 910 PHE A C   1 
ATOM 2167 O O   . PHE A 1 329 ? 112.352 112.846 142.305 1.00 101.46 ? 910 PHE A O   1 
ATOM 2168 C CB  . PHE A 1 329 ? 109.291 111.279 141.872 1.00 101.46 ? 910 PHE A CB  1 
ATOM 2169 C CG  . PHE A 1 329 ? 108.214 110.750 140.973 1.00 101.46 ? 910 PHE A CG  1 
ATOM 2170 C CD1 . PHE A 1 329 ? 108.408 109.595 140.231 1.00 101.46 ? 910 PHE A CD1 1 
ATOM 2171 C CD2 . PHE A 1 329 ? 107.001 111.416 140.873 1.00 101.46 ? 910 PHE A CD2 1 
ATOM 2172 C CE1 . PHE A 1 329 ? 107.404 109.108 139.410 1.00 101.46 ? 910 PHE A CE1 1 
ATOM 2173 C CE2 . PHE A 1 329 ? 105.996 110.939 140.052 1.00 101.46 ? 910 PHE A CE2 1 
ATOM 2174 C CZ  . PHE A 1 329 ? 106.198 109.783 139.321 1.00 101.46 ? 910 PHE A CZ  1 
ATOM 2175 N N   . ARG A 1 330 ? 110.415 113.866 142.805 1.00 108.44 ? 911 ARG A N   1 
ATOM 2176 C CA  . ARG A 1 330 ? 111.013 114.632 143.892 1.00 108.44 ? 911 ARG A CA  1 
ATOM 2177 C C   . ARG A 1 330 ? 111.018 113.817 145.178 1.00 108.44 ? 911 ARG A C   1 
ATOM 2178 O O   . ARG A 1 330 ? 112.063 113.651 145.819 1.00 108.44 ? 911 ARG A O   1 
ATOM 2179 C CB  . ARG A 1 330 ? 110.250 115.946 144.088 1.00 108.44 ? 911 ARG A CB  1 
ATOM 2180 C CG  . ARG A 1 330 ? 110.455 116.603 145.451 1.00 108.44 ? 911 ARG A CG  1 
ATOM 2181 C CD  . ARG A 1 330 ? 109.333 117.576 145.784 1.00 108.44 ? 911 ARG A CD  1 
ATOM 2182 N NE  . ARG A 1 330 ? 109.095 118.544 144.722 1.00 108.44 ? 911 ARG A NE  1 
ATOM 2183 C CZ  . ARG A 1 330 ? 108.051 119.360 144.674 1.00 108.44 ? 911 ARG A CZ  1 
ATOM 2184 N NH1 . ARG A 1 330 ? 107.120 119.347 145.614 1.00 108.44 ? 911 ARG A NH1 1 
ATOM 2185 N NH2 . ARG A 1 330 ? 107.938 120.210 143.658 1.00 108.44 ? 911 ARG A NH2 1 
ATOM 2186 N N   . ASP A 1 331 ? 109.855 113.285 145.557 1.00 118.57 ? 912 ASP A N   1 
ATOM 2187 C CA  . ASP A 1 331 ? 109.678 112.549 146.802 1.00 118.57 ? 912 ASP A CA  1 
ATOM 2188 C C   . ASP A 1 331 ? 108.455 111.644 146.728 1.00 118.57 ? 912 ASP A C   1 
ATOM 2189 O O   . ASP A 1 331 ? 107.942 111.370 145.638 1.00 118.57 ? 912 ASP A O   1 
ATOM 2190 C CB  . ASP A 1 331 ? 109.575 113.517 147.989 1.00 118.57 ? 912 ASP A CB  1 
ATOM 2191 C CG  . ASP A 1 331 ? 108.505 114.585 147.798 1.00 118.57 ? 912 ASP A CG  1 
ATOM 2192 O OD1 . ASP A 1 331 ? 107.917 114.688 146.700 1.00 118.57 ? 912 ASP A OD1 1 
ATOM 2193 O OD2 . ASP A 1 331 ? 108.255 115.338 148.762 1.00 118.57 ? 912 ASP A OD2 1 
ATOM 2194 N N   . CYS A 1 332 ? 107.990 111.169 147.885 1.00 120.38 ? 913 CYS A N   1 
ATOM 2195 C CA  . CYS A 1 332 ? 106.774 110.363 147.925 1.00 120.38 ? 913 CYS A CA  1 
ATOM 2196 C C   . CYS A 1 332 ? 105.534 111.213 147.660 1.00 120.38 ? 913 CYS A C   1 
ATOM 2197 O O   . CYS A 1 332 ? 104.537 110.715 147.121 1.00 120.38 ? 913 CYS A O   1 
ATOM 2198 C CB  . CYS A 1 332 ? 106.670 109.656 149.278 1.00 120.38 ? 913 CYS A CB  1 
ATOM 2199 S SG  . CYS A 1 332 ? 105.252 108.550 149.476 1.00 120.38 ? 913 CYS A SG  1 
ATOM 2200 N N   . GLU A 1 333 ? 105.589 112.501 148.022 1.00 121.32 ? 914 GLU A N   1 
ATOM 2201 C CA  . GLU A 1 333 ? 104.417 113.374 147.962 1.00 121.32 ? 914 GLU A CA  1 
ATOM 2202 C C   . GLU A 1 333 ? 104.012 113.681 146.523 1.00 121.32 ? 914 GLU A C   1 
ATOM 2203 O O   . GLU A 1 333 ? 102.821 113.789 146.209 1.00 121.32 ? 914 GLU A O   1 
ATOM 2204 C CB  . GLU A 1 333 ? 104.692 114.669 148.728 1.00 121.32 ? 914 GLU A CB  1 
ATOM 2205 C CG  . GLU A 1 333 ? 105.088 114.468 150.182 1.00 121.32 ? 914 GLU A CG  1 
ATOM 2206 C CD  . GLU A 1 333 ? 105.790 115.679 150.765 1.00 121.32 ? 914 GLU A CD  1 
ATOM 2207 O OE1 . GLU A 1 333 ? 105.264 116.802 150.617 1.00 121.32 ? 914 GLU A OE1 1 
ATOM 2208 O OE2 . GLU A 1 333 ? 106.867 115.508 151.375 1.00 121.32 ? 914 GLU A OE2 1 
ATOM 2209 N N   . GLU A 1 334 ? 104.993 113.832 145.633 1.00 116.12 ? 915 GLU A N   1 
ATOM 2210 C CA  . GLU A 1 334 ? 104.673 114.029 144.223 1.00 116.12 ? 915 GLU A CA  1 
ATOM 2211 C C   . GLU A 1 334 ? 104.252 112.717 143.573 1.00 116.12 ? 915 GLU A C   1 
ATOM 2212 O O   . GLU A 1 334 ? 103.392 112.699 142.684 1.00 116.12 ? 915 GLU A O   1 
ATOM 2213 C CB  . GLU A 1 334 ? 105.868 114.638 143.488 1.00 116.12 ? 915 GLU A CB  1 
ATOM 2214 C CG  . GLU A 1 334 ? 105.478 115.542 142.327 1.00 116.12 ? 915 GLU A CG  1 
ATOM 2215 C CD  . GLU A 1 334 ? 106.637 115.829 141.393 1.00 116.12 ? 915 GLU A CD  1 
ATOM 2216 O OE1 . GLU A 1 334 ? 106.489 116.701 140.510 1.00 116.12 ? 915 GLU A OE1 1 
ATOM 2217 O OE2 . GLU A 1 334 ? 107.696 115.184 141.540 1.00 116.12 ? 915 GLU A OE2 1 
ATOM 2218 N N   . ALA A 1 335 ? 104.831 111.602 144.030 1.00 112.64 ? 916 ALA A N   1 
ATOM 2219 C CA  . ALA A 1 335 ? 104.584 110.304 143.405 1.00 112.64 ? 916 ALA A CA  1 
ATOM 2220 C C   . ALA A 1 335 ? 103.180 109.790 143.705 1.00 112.64 ? 916 ALA A C   1 
ATOM 2221 O O   . ALA A 1 335 ? 102.509 109.248 142.817 1.00 112.64 ? 916 ALA A O   1 
ATOM 2222 C CB  . ALA A 1 335 ? 105.637 109.296 143.865 1.00 112.64 ? 916 ALA A CB  1 
ATOM 2223 N N   . THR A 1 336 ? 102.719 109.955 144.951 1.00 116.04 ? 917 THR A N   1 
ATOM 2224 C CA  . THR A 1 336 ? 101.364 109.534 145.301 1.00 116.04 ? 917 THR A CA  1 
ATOM 2225 C C   . THR A 1 336 ? 100.312 110.386 144.601 1.00 116.04 ? 917 THR A C   1 
ATOM 2226 O O   . THR A 1 336 ? 99.281  109.869 144.162 1.00 116.04 ? 917 THR A O   1 
ATOM 2227 C CB  . THR A 1 336 ? 101.162 109.574 146.817 1.00 116.04 ? 917 THR A CB  1 
ATOM 2228 O OG1 . THR A 1 336 ? 101.437 110.892 147.310 1.00 116.04 ? 917 THR A OG1 1 
ATOM 2229 C CG2 . THR A 1 336 ? 102.053 108.551 147.510 1.00 116.04 ? 917 THR A CG2 1 
ATOM 2230 N N   . ASP A 1 337 ? 100.578 111.686 144.448 1.00 115.08 ? 918 ASP A N   1 
ATOM 2231 C CA  . ASP A 1 337 ? 99.651  112.552 143.727 1.00 115.08 ? 918 ASP A CA  1 
ATOM 2232 C C   . ASP A 1 337 ? 99.671  112.261 142.228 1.00 115.08 ? 918 ASP A C   1 
ATOM 2233 O O   . ASP A 1 337 ? 98.657  112.440 141.543 1.00 115.08 ? 918 ASP A O   1 
ATOM 2234 C CB  . ASP A 1 337 ? 99.991  114.018 144.000 1.00 115.08 ? 918 ASP A CB  1 
ATOM 2235 C CG  . ASP A 1 337 ? 98.772  114.923 143.956 1.00 115.08 ? 918 ASP A CG  1 
ATOM 2236 O OD1 . ASP A 1 337 ? 97.747  114.533 143.359 1.00 115.08 ? 918 ASP A OD1 1 
ATOM 2237 O OD2 . ASP A 1 337 ? 98.839  116.033 144.525 1.00 115.08 ? 918 ASP A OD2 1 
ATOM 2238 N N   . PHE A 1 338 ? 100.811 111.803 141.704 1.00 109.22 ? 919 PHE A N   1 
ATOM 2239 C CA  . PHE A 1 338 ? 100.892 111.490 140.281 1.00 109.22 ? 919 PHE A CA  1 
ATOM 2240 C C   . PHE A 1 338 ? 100.187 110.174 139.963 1.00 109.22 ? 919 PHE A C   1 
ATOM 2241 O O   . PHE A 1 338 ? 99.529  110.053 138.924 1.00 109.22 ? 919 PHE A O   1 
ATOM 2242 C CB  . PHE A 1 338 ? 102.362 111.457 139.848 1.00 109.22 ? 919 PHE A CB  1 
ATOM 2243 C CG  . PHE A 1 338 ? 102.574 111.198 138.377 1.00 109.22 ? 919 PHE A CG  1 
ATOM 2244 C CD1 . PHE A 1 338 ? 102.897 109.928 137.910 1.00 109.22 ? 919 PHE A CD1 1 
ATOM 2245 C CD2 . PHE A 1 338 ? 102.475 112.240 137.463 1.00 109.22 ? 919 PHE A CD2 1 
ATOM 2246 C CE1 . PHE A 1 338 ? 103.100 109.698 136.558 1.00 109.22 ? 919 PHE A CE1 1 
ATOM 2247 C CE2 . PHE A 1 338 ? 102.679 112.018 136.108 1.00 109.22 ? 919 PHE A CE2 1 
ATOM 2248 C CZ  . PHE A 1 338 ? 102.994 110.745 135.658 1.00 109.22 ? 919 PHE A CZ  1 
ATOM 2249 N N   . LEU A 1 339 ? 100.313 109.173 140.841 1.00 106.08 ? 920 LEU A N   1 
ATOM 2250 C CA  . LEU A 1 339 ? 99.708  107.874 140.544 1.00 106.08 ? 920 LEU A CA  1 
ATOM 2251 C C   . LEU A 1 339 ? 98.277  107.759 141.070 1.00 106.08 ? 920 LEU A C   1 
ATOM 2252 O O   . LEU A 1 339 ? 97.561  106.820 140.704 1.00 106.08 ? 920 LEU A O   1 
ATOM 2253 C CB  . LEU A 1 339 ? 100.574 106.726 141.076 1.00 106.08 ? 920 LEU A CB  1 
ATOM 2254 C CG  . LEU A 1 339 ? 101.805 106.252 140.278 1.00 106.08 ? 920 LEU A CG  1 
ATOM 2255 C CD1 . LEU A 1 339 ? 103.008 107.182 140.300 1.00 106.08 ? 920 LEU A CD1 1 
ATOM 2256 C CD2 . LEU A 1 339 ? 102.215 104.861 140.734 1.00 106.08 ? 920 LEU A CD2 1 
ATOM 2257 N N   . THR A 1 340 ? 97.834  108.681 141.930 1.00 110.29 ? 921 THR A N   1 
ATOM 2258 C CA  . THR A 1 340 ? 96.419  108.683 142.301 1.00 110.29 ? 921 THR A CA  1 
ATOM 2259 C C   . THR A 1 340 ? 95.531  109.185 141.167 1.00 110.29 ? 921 THR A C   1 
ATOM 2260 O O   . THR A 1 340 ? 94.444  108.634 140.951 1.00 110.29 ? 921 THR A O   1 
ATOM 2261 C CB  . THR A 1 340 ? 96.191  109.520 143.568 1.00 110.29 ? 921 THR A CB  1 
ATOM 2262 O OG1 . THR A 1 340 ? 97.165  109.169 144.556 1.00 110.29 ? 921 THR A OG1 1 
ATOM 2263 C CG2 . THR A 1 340 ? 94.804  109.281 144.155 1.00 110.29 ? 921 THR A CG2 1 
ATOM 2264 N N   . CYS A 1 341 ? 95.985  110.189 140.414 1.00 112.77 ? 922 CYS A N   1 
ATOM 2265 C CA  . CYS A 1 341 ? 95.159  110.777 139.364 1.00 112.77 ? 922 CYS A CA  1 
ATOM 2266 C C   . CYS A 1 341 ? 95.039  109.880 138.137 1.00 112.77 ? 922 CYS A C   1 
ATOM 2267 O O   . CYS A 1 341 ? 94.107  110.050 137.344 1.00 112.77 ? 922 CYS A O   1 
ATOM 2268 C CB  . CYS A 1 341 ? 95.721  112.140 138.958 1.00 112.77 ? 922 CYS A CB  1 
ATOM 2269 S SG  . CYS A 1 341 ? 97.134  112.062 137.838 1.00 112.77 ? 922 CYS A SG  1 
ATOM 2270 N N   . HIS A 1 342 ? 95.962  108.931 137.958 1.00 107.67 ? 923 HIS A N   1 
ATOM 2271 C CA  . HIS A 1 342 ? 95.912  108.081 136.773 1.00 107.67 ? 923 HIS A CA  1 
ATOM 2272 C C   . HIS A 1 342 ? 94.878  106.970 136.923 1.00 107.67 ? 923 HIS A C   1 
ATOM 2273 O O   . HIS A 1 342 ? 94.316  106.503 135.927 1.00 107.67 ? 923 HIS A O   1 
ATOM 2274 C CB  . HIS A 1 342 ? 97.296  107.507 136.479 1.00 107.67 ? 923 HIS A CB  1 
ATOM 2275 C CG  . HIS A 1 342 ? 98.223  108.490 135.838 1.00 107.67 ? 923 HIS A CG  1 
ATOM 2276 N ND1 . HIS A 1 342 ? 97.778  109.501 135.013 1.00 107.67 ? 923 HIS A ND1 1 
ATOM 2277 C CD2 . HIS A 1 342 ? 99.570  108.617 135.894 1.00 107.67 ? 923 HIS A CD2 1 
ATOM 2278 C CE1 . HIS A 1 342 ? 98.809  110.213 134.596 1.00 107.67 ? 923 HIS A CE1 1 
ATOM 2279 N NE2 . HIS A 1 342 ? 99.909  109.694 135.112 1.00 107.67 ? 923 HIS A NE2 1 
ATOM 2280 N N   . GLY A 1 343 ? 94.615  106.532 138.153 1.00 110.24 ? 924 GLY A N   1 
ATOM 2281 C CA  . GLY A 1 343 ? 93.537  105.591 138.384 1.00 110.24 ? 924 GLY A CA  1 
ATOM 2282 C C   . GLY A 1 343 ? 93.897  104.363 139.195 1.00 110.24 ? 924 GLY A C   1 
ATOM 2283 O O   . GLY A 1 343 ? 93.031  103.528 139.472 1.00 110.24 ? 924 GLY A O   1 
ATOM 2284 N N   . LEU A 1 344 ? 95.164  104.234 139.585 1.00 107.67 ? 925 LEU A N   1 
ATOM 2285 C CA  . LEU A 1 344 ? 95.611  103.096 140.371 1.00 107.67 ? 925 LEU A CA  1 
ATOM 2286 C C   . LEU A 1 344 ? 95.801  103.517 141.833 1.00 107.67 ? 925 LEU A C   1 
ATOM 2287 O O   . LEU A 1 344 ? 95.730  104.709 142.165 1.00 107.67 ? 925 LEU A O   1 
ATOM 2288 C CB  . LEU A 1 344 ? 96.876  102.484 139.742 1.00 107.67 ? 925 LEU A CB  1 
ATOM 2289 C CG  . LEU A 1 344 ? 98.282  103.098 139.761 1.00 107.67 ? 925 LEU A CG  1 
ATOM 2290 C CD1 . LEU A 1 344 ? 99.282  102.025 139.386 1.00 107.67 ? 925 LEU A CD1 1 
ATOM 2291 C CD2 . LEU A 1 344 ? 98.433  104.250 138.782 1.00 107.67 ? 925 LEU A CD2 1 
ATOM 2292 N N   . THR A 1 345 ? 96.040  102.537 142.703 1.00 114.34 ? 926 THR A N   1 
ATOM 2293 C CA  . THR A 1 345 ? 96.025  102.734 144.145 1.00 114.34 ? 926 THR A CA  1 
ATOM 2294 C C   . THR A 1 345 ? 97.453  102.748 144.676 1.00 114.34 ? 926 THR A C   1 
ATOM 2295 O O   . THR A 1 345 ? 98.257  101.864 144.367 1.00 114.34 ? 926 THR A O   1 
ATOM 2296 C CB  . THR A 1 345 ? 95.196  101.629 144.832 1.00 114.34 ? 926 THR A CB  1 
ATOM 2297 O OG1 . THR A 1 345 ? 93.884  101.592 144.257 1.00 114.34 ? 926 THR A OG1 1 
ATOM 2298 C CG2 . THR A 1 345 ? 95.064  101.885 146.320 1.00 114.34 ? 926 THR A CG2 1 
ATOM 2299 N N   . VAL A 1 346 ? 97.763  103.768 145.479 1.00 116.75 ? 927 VAL A N   1 
ATOM 2300 C CA  . VAL A 1 346 ? 99.124  104.008 145.951 1.00 116.75 ? 927 VAL A CA  1 
ATOM 2301 C C   . VAL A 1 346 ? 99.067  104.049 147.481 1.00 116.75 ? 927 VAL A C   1 
ATOM 2302 O O   . VAL A 1 346 ? 100.070 104.300 148.161 1.00 116.75 ? 927 VAL A O   1 
ATOM 2303 C CB  . VAL A 1 346 ? 99.672  105.314 145.323 1.00 116.75 ? 927 VAL A CB  1 
ATOM 2304 C CG1 . VAL A 1 346 ? 98.898  106.542 145.815 1.00 116.75 ? 927 VAL A CG1 1 
ATOM 2305 C CG2 . VAL A 1 346 ? 101.218 105.458 145.384 1.00 116.75 ? 927 VAL A CG2 1 
ATOM 2306 N N   . SER A 1 347 ? 97.891  103.756 148.035 1.00 120.05 ? 928 SER A N   1 
ATOM 2307 C CA  . SER A 1 347 ? 97.669  103.921 149.468 1.00 120.05 ? 928 SER A CA  1 
ATOM 2308 C C   . SER A 1 347 ? 98.329  102.806 150.273 1.00 120.05 ? 928 SER A C   1 
ATOM 2309 O O   . SER A 1 347 ? 98.804  101.811 149.714 1.00 120.05 ? 928 SER A O   1 
ATOM 2310 C CB  . SER A 1 347 ? 96.171  103.957 149.772 1.00 120.05 ? 928 SER A CB  1 
ATOM 2311 O OG  . SER A 1 347 ? 95.568  102.701 149.519 1.00 120.05 ? 928 SER A OG  1 
ATOM 2312 N N   . ASP A 1 348 ? 98.372  103.018 151.597 1.00 127.26 ? 929 ASP A N   1 
ATOM 2313 C CA  . ASP A 1 348 ? 98.862  102.087 152.627 1.00 127.26 ? 929 ASP A CA  1 
ATOM 2314 C C   . ASP A 1 348 ? 100.346 101.818 152.401 1.00 127.26 ? 929 ASP A C   1 
ATOM 2315 O O   . ASP A 1 348 ? 101.135 102.780 152.408 1.00 127.26 ? 929 ASP A O   1 
ATOM 2316 C CB  . ASP A 1 348 ? 97.959  100.848 152.681 1.00 127.26 ? 929 ASP A CB  1 
ATOM 2317 N N   . GLY A 1 349 ? 100.774 100.572 152.196 1.00 130.92 ? 930 GLY A N   1 
ATOM 2318 C CA  . GLY A 1 349 ? 102.195 100.273 152.235 1.00 130.92 ? 930 GLY A CA  1 
ATOM 2319 C C   . GLY A 1 349 ? 102.880 100.331 150.884 1.00 130.92 ? 930 GLY A C   1 
ATOM 2320 O O   . GLY A 1 349 ? 104.049 100.717 150.796 1.00 130.92 ? 930 GLY A O   1 
ATOM 2321 N N   . CYS A 1 350 ? 102.178 99.954  149.819 1.00 120.53 ? 931 CYS A N   1 
ATOM 2322 C CA  . CYS A 1 350 ? 102.839 99.789  148.533 1.00 120.53 ? 931 CYS A CA  1 
ATOM 2323 C C   . CYS A 1 350 ? 101.880 100.138 147.405 1.00 120.53 ? 931 CYS A C   1 
ATOM 2324 O O   . CYS A 1 350 ? 100.692 100.382 147.632 1.00 120.53 ? 931 CYS A O   1 
ATOM 2325 C CB  . CYS A 1 350 ? 103.364 98.361  148.365 1.00 120.53 ? 931 CYS A CB  1 
ATOM 2326 N N   . VAL A 1 351 ? 102.418 100.157 146.187 1.00 111.14 ? 932 VAL A N   1 
ATOM 2327 C CA  . VAL A 1 351 ? 101.658 100.579 145.015 1.00 111.14 ? 932 VAL A CA  1 
ATOM 2328 C C   . VAL A 1 351 ? 100.940 99.375  144.417 1.00 111.14 ? 932 VAL A C   1 
ATOM 2329 O O   . VAL A 1 351 ? 101.561 98.347  144.122 1.00 111.14 ? 932 VAL A O   1 
ATOM 2330 C CB  . VAL A 1 351 ? 102.576 101.245 143.983 1.00 111.14 ? 932 VAL A CB  1 
ATOM 2331 C CG1 . VAL A 1 351 ? 101.778 101.719 142.780 1.00 111.14 ? 932 VAL A CG1 1 
ATOM 2332 C CG2 . VAL A 1 351 ? 103.338 102.398 144.617 1.00 111.14 ? 932 VAL A CG2 1 
ATOM 2333 N N   . GLU A 1 352 ? 99.628  99.500  144.237 1.00 106.19 ? 933 GLU A N   1 
ATOM 2334 C CA  . GLU A 1 352 ? 98.837  98.454  143.611 1.00 106.19 ? 933 GLU A CA  1 
ATOM 2335 C C   . GLU A 1 352 ? 99.086  98.427  142.103 1.00 106.19 ? 933 GLU A C   1 
ATOM 2336 O O   . GLU A 1 352 ? 99.496  99.417  141.493 1.00 106.19 ? 933 GLU A O   1 
ATOM 2337 C CB  . GLU A 1 352 ? 97.352  98.671  143.897 1.00 106.19 ? 933 GLU A CB  1 
ATOM 2338 C CG  . GLU A 1 352 ? 96.898  98.158  145.249 1.00 106.19 ? 933 GLU A CG  1 
ATOM 2339 C CD  . GLU A 1 352 ? 96.688  96.663  145.258 1.00 106.19 ? 933 GLU A CD  1 
ATOM 2340 O OE1 . GLU A 1 352 ? 95.907  96.175  144.416 1.00 106.19 ? 933 GLU A OE1 1 
ATOM 2341 O OE2 . GLU A 1 352 ? 97.302  95.977  146.101 1.00 106.19 ? 933 GLU A OE2 1 
ATOM 2342 N N   . LEU A 1 353 ? 98.840  97.263  141.500 1.00 97.00  ? 934 LEU A N   1 
ATOM 2343 C CA  . LEU A 1 353 ? 98.956  97.099  140.055 1.00 97.00  ? 934 LEU A CA  1 
ATOM 2344 C C   . LEU A 1 353 ? 97.768  96.287  139.561 1.00 97.00  ? 934 LEU A C   1 
ATOM 2345 O O   . LEU A 1 353 ? 97.506  95.197  140.078 1.00 97.00  ? 934 LEU A O   1 
ATOM 2346 C CB  . LEU A 1 353 ? 100.272 96.406  139.671 1.00 97.00  ? 934 LEU A CB  1 
ATOM 2347 C CG  . LEU A 1 353 ? 101.596 97.129  139.933 1.00 97.00  ? 934 LEU A CG  1 
ATOM 2348 C CD1 . LEU A 1 353 ? 102.776 96.229  139.619 1.00 97.00  ? 934 LEU A CD1 1 
ATOM 2349 C CD2 . LEU A 1 353 ? 101.678 98.406  139.116 1.00 97.00  ? 934 LEU A CD2 1 
ATOM 2350 N N   . ASN A 1 354 ? 97.060  96.814  138.564 1.00 99.17  ? 935 ASN A N   1 
ATOM 2351 C CA  . ASN A 1 354 ? 95.894  96.140  138.009 1.00 99.17  ? 935 ASN A CA  1 
ATOM 2352 C C   . ASN A 1 354 ? 95.706  96.586  136.567 1.00 99.17  ? 935 ASN A C   1 
ATOM 2353 O O   . ASN A 1 354 ? 95.873  97.766  136.249 1.00 99.17  ? 935 ASN A O   1 
ATOM 2354 C CB  . ASN A 1 354 ? 94.637  96.432  138.841 1.00 99.17  ? 935 ASN A CB  1 
ATOM 2355 C CG  . ASN A 1 354 ? 93.397  95.743  138.298 1.00 99.17  ? 935 ASN A CG  1 
ATOM 2356 O OD1 . ASN A 1 354 ? 92.707  96.270  137.425 1.00 99.17  ? 935 ASN A OD1 1 
ATOM 2357 N ND2 . ASN A 1 354 ? 93.112  94.553  138.812 1.00 99.17  ? 935 ASN A ND2 1 
ATOM 2358 N N   . ARG A 1 355 ? 95.363  95.631  135.699 1.00 96.63  ? 936 ARG A N   1 
ATOM 2359 C CA  . ARG A 1 355 ? 95.203  95.934  134.279 1.00 96.63  ? 936 ARG A CA  1 
ATOM 2360 C C   . ARG A 1 355 ? 93.905  96.683  134.004 1.00 96.63  ? 936 ARG A C   1 
ATOM 2361 O O   . ARG A 1 355 ? 93.882  97.622  133.200 1.00 96.63  ? 936 ARG A O   1 
ATOM 2362 C CB  . ARG A 1 355 ? 95.249  94.643  133.463 1.00 96.63  ? 936 ARG A CB  1 
ATOM 2363 C CG  . ARG A 1 355 ? 96.529  93.855  133.632 1.00 96.63  ? 936 ARG A CG  1 
ATOM 2364 C CD  . ARG A 1 355 ? 97.483  94.075  132.472 1.00 96.63  ? 936 ARG A CD  1 
ATOM 2365 N NE  . ARG A 1 355 ? 97.221  93.146  131.380 1.00 96.63  ? 936 ARG A NE  1 
ATOM 2366 C CZ  . ARG A 1 355 ? 97.860  91.997  131.207 1.00 96.63  ? 936 ARG A CZ  1 
ATOM 2367 N NH1 . ARG A 1 355 ? 98.825  91.613  132.025 1.00 96.63  ? 936 ARG A NH1 1 
ATOM 2368 N NH2 . ARG A 1 355 ? 97.523  91.214  130.187 1.00 96.63  ? 936 ARG A NH2 1 
ATOM 2369 N N   . SER A 1 356 ? 92.813  96.275  134.655 1.00 106.58 ? 937 SER A N   1 
ATOM 2370 C CA  . SER A 1 356 ? 91.496  96.801  134.308 1.00 106.58 ? 937 SER A CA  1 
ATOM 2371 C C   . SER A 1 356 ? 91.291  98.208  134.859 1.00 106.58 ? 937 SER A C   1 
ATOM 2372 O O   . SER A 1 356 ? 90.539  99.007  134.289 1.00 106.58 ? 937 SER A O   1 
ATOM 2373 C CB  . SER A 1 356 ? 90.407  95.853  134.817 1.00 106.58 ? 937 SER A CB  1 
ATOM 2374 O OG  . SER A 1 356 ? 90.208  95.994  136.213 1.00 106.58 ? 937 SER A OG  1 
ATOM 2375 N N   . ALA A 1 357 ? 91.963  98.535  135.961 1.00 106.97 ? 938 ALA A N   1 
ATOM 2376 C CA  . ALA A 1 357 ? 91.755  99.796  136.671 1.00 106.97 ? 938 ALA A CA  1 
ATOM 2377 C C   . ALA A 1 357 ? 92.756  100.868 136.256 1.00 106.97 ? 938 ALA A C   1 
ATOM 2378 O O   . ALA A 1 357 ? 93.099  101.749 137.052 1.00 106.97 ? 938 ALA A O   1 
ATOM 2379 C CB  . ALA A 1 357 ? 91.810  99.564  138.177 1.00 106.97 ? 938 ALA A CB  1 
ATOM 2380 N N   . PHE A 1 358 ? 93.236  100.821 135.017 1.00 105.17 ? 939 PHE A N   1 
ATOM 2381 C CA  . PHE A 1 358 ? 94.183  101.800 134.501 1.00 105.17 ? 939 PHE A CA  1 
ATOM 2382 C C   . PHE A 1 358 ? 93.611  102.344 133.199 1.00 105.17 ? 939 PHE A C   1 
ATOM 2383 O O   . PHE A 1 358 ? 93.224  101.569 132.318 1.00 105.17 ? 939 PHE A O   1 
ATOM 2384 C CB  . PHE A 1 358 ? 95.577  101.157 134.350 1.00 105.17 ? 939 PHE A CB  1 
ATOM 2385 C CG  . PHE A 1 358 ? 96.561  101.921 133.482 1.00 105.17 ? 939 PHE A CG  1 
ATOM 2386 C CD1 . PHE A 1 358 ? 97.512  102.724 134.090 1.00 105.17 ? 939 PHE A CD1 1 
ATOM 2387 C CD2 . PHE A 1 358 ? 96.677  101.688 132.105 1.00 105.17 ? 939 PHE A CD2 1 
ATOM 2388 C CE1 . PHE A 1 358 ? 98.452  103.409 133.342 1.00 105.17 ? 939 PHE A CE1 1 
ATOM 2389 C CE2 . PHE A 1 358 ? 97.621  102.369 131.349 1.00 105.17 ? 939 PHE A CE2 1 
ATOM 2390 C CZ  . PHE A 1 358 ? 98.514  103.224 131.972 1.00 105.17 ? 939 PHE A CZ  1 
ATOM 2391 N N   . LEU A 1 359 ? 93.555  103.670 133.083 1.00 106.70 ? 940 LEU A N   1 
ATOM 2392 C CA  . LEU A 1 359 ? 93.035  104.334 131.897 1.00 106.70 ? 940 LEU A CA  1 
ATOM 2393 C C   . LEU A 1 359 ? 93.924  105.517 131.542 1.00 106.70 ? 940 LEU A C   1 
ATOM 2394 O O   . LEU A 1 359 ? 94.705  106.004 132.362 1.00 106.70 ? 940 LEU A O   1 
ATOM 2395 C CB  . LEU A 1 359 ? 91.580  104.820 132.073 1.00 106.70 ? 940 LEU A CB  1 
ATOM 2396 C CG  . LEU A 1 359 ? 91.214  106.046 132.927 1.00 106.70 ? 940 LEU A CG  1 
ATOM 2397 C CD1 . LEU A 1 359 ? 89.804  106.500 132.581 1.00 106.70 ? 940 LEU A CD1 1 
ATOM 2398 C CD2 . LEU A 1 359 ? 91.304  105.788 134.426 1.00 106.70 ? 940 LEU A CD2 1 
ATOM 2399 N N   . GLU A 1 360 ? 93.790  105.975 130.297 1.00 119.93 ? 941 GLU A N   1 
ATOM 2400 C CA  . GLU A 1 360 ? 94.575  107.088 129.792 1.00 119.93 ? 941 GLU A CA  1 
ATOM 2401 C C   . GLU A 1 360 ? 94.073  108.404 130.384 1.00 119.93 ? 941 GLU A C   1 
ATOM 2402 O O   . GLU A 1 360 ? 92.874  108.577 130.614 1.00 119.93 ? 941 GLU A O   1 
ATOM 2403 C CB  . GLU A 1 360 ? 94.512  107.122 128.265 1.00 119.93 ? 941 GLU A CB  1 
ATOM 2404 N N   . PRO A 1 361 ? 94.970  109.356 130.647 1.00 126.20 ? 942 PRO A N   1 
ATOM 2405 C CA  . PRO A 1 361 ? 94.528  110.641 131.195 1.00 126.20 ? 942 PRO A CA  1 
ATOM 2406 C C   . PRO A 1 361 ? 94.162  111.628 130.099 1.00 126.20 ? 942 PRO A C   1 
ATOM 2407 O O   . PRO A 1 361 ? 94.517  111.459 128.930 1.00 126.20 ? 942 PRO A O   1 
ATOM 2408 C CB  . PRO A 1 361 ? 95.745  111.122 131.988 1.00 126.20 ? 942 PRO A CB  1 
ATOM 2409 C CG  . PRO A 1 361 ? 96.906  110.543 131.256 1.00 126.20 ? 942 PRO A CG  1 
ATOM 2410 C CD  . PRO A 1 361 ? 96.441  109.272 130.577 1.00 126.20 ? 942 PRO A CD  1 
ATOM 2411 N N   . GLU A 1 362 ? 93.444  112.675 130.500 1.00 149.31 ? 943 GLU A N   1 
ATOM 2412 C CA  . GLU A 1 362 ? 93.017  113.719 129.580 1.00 149.31 ? 943 GLU A CA  1 
ATOM 2413 C C   . GLU A 1 362 ? 92.779  114.996 130.370 1.00 149.31 ? 943 GLU A C   1 
ATOM 2414 O O   . GLU A 1 362 ? 92.697  114.982 131.600 1.00 149.31 ? 943 GLU A O   1 
ATOM 2415 C CB  . GLU A 1 362 ? 91.750  113.316 128.816 1.00 149.31 ? 943 GLU A CB  1 
ATOM 2416 N N   . GLY A 1 363 ? 92.673  116.103 129.642 1.00 156.90 ? 944 GLY A N   1 
ATOM 2417 C CA  . GLY A 1 363 ? 92.358  117.367 130.287 1.00 156.90 ? 944 GLY A CA  1 
ATOM 2418 C C   . GLY A 1 363 ? 93.599  118.044 130.832 1.00 156.90 ? 944 GLY A C   1 
ATOM 2419 O O   . GLY A 1 363 ? 94.585  118.258 130.118 1.00 156.90 ? 944 GLY A O   1 
ATOM 2420 N N   . LEU A 1 364 ? 93.553  118.390 132.117 1.00 157.64 ? 945 LEU A N   1 
ATOM 2421 C CA  . LEU A 1 364 ? 94.641  119.134 132.737 1.00 157.64 ? 945 LEU A CA  1 
ATOM 2422 C C   . LEU A 1 364 ? 95.821  118.216 133.036 1.00 157.64 ? 945 LEU A C   1 
ATOM 2423 O O   . LEU A 1 364 ? 95.670  117.181 133.693 1.00 157.64 ? 945 LEU A O   1 
ATOM 2424 C CB  . LEU A 1 364 ? 94.157  119.808 134.020 1.00 157.64 ? 945 LEU A CB  1 
ATOM 2425 N N   . SER A 1 365 ? 96.999  118.603 132.549 1.00 150.81 ? 946 SER A N   1 
ATOM 2426 C CA  . SER A 1 365 ? 98.231  117.848 132.741 1.00 150.81 ? 946 SER A CA  1 
ATOM 2427 C C   . SER A 1 365 ? 99.348  118.817 133.135 1.00 150.81 ? 946 SER A C   1 
ATOM 2428 O O   . SER A 1 365 ? 100.423 118.838 132.541 1.00 150.81 ? 946 SER A O   1 
ATOM 2429 C CB  . SER A 1 365 ? 98.591  117.055 131.487 1.00 150.81 ? 946 SER A CB  1 
ATOM 2430 O OG  . SER A 1 365 ? 97.525  116.209 131.094 1.00 150.81 ? 946 SER A OG  1 
ATOM 2431 N N   . LYS A 1 366 ? 99.063  119.657 134.133 1.00 137.49 ? 947 LYS A N   1 
ATOM 2432 C CA  . LYS A 1 366 ? 99.999  120.694 134.555 1.00 137.49 ? 947 LYS A CA  1 
ATOM 2433 C C   . LYS A 1 366 ? 101.229 120.096 135.233 1.00 137.49 ? 947 LYS A C   1 
ATOM 2434 O O   . LYS A 1 366 ? 101.161 119.052 135.889 1.00 137.49 ? 947 LYS A O   1 
ATOM 2435 C CB  . LYS A 1 366 ? 99.295  121.694 135.482 1.00 137.49 ? 947 LYS A CB  1 
ATOM 2436 C CG  . LYS A 1 366 ? 98.801  121.126 136.809 1.00 137.49 ? 947 LYS A CG  1 
ATOM 2437 C CD  . LYS A 1 366 ? 98.084  122.182 137.634 1.00 137.49 ? 947 LYS A CD  1 
ATOM 2438 C CE  . LYS A 1 366 ? 97.554  121.598 138.933 1.00 137.49 ? 947 LYS A CE  1 
ATOM 2439 N NZ  . LYS A 1 366 ? 98.655  121.191 139.848 1.00 137.49 ? 947 LYS A NZ  1 
ATOM 2440 N N   . THR A 1 367 ? 102.372 120.744 135.023 1.00 128.88 ? 948 THR A N   1 
ATOM 2441 C CA  . THR A 1 367 ? 103.654 120.227 135.480 1.00 128.88 ? 948 THR A CA  1 
ATOM 2442 C C   . THR A 1 367 ? 104.130 121.029 136.693 1.00 128.88 ? 948 THR A C   1 
ATOM 2443 O O   . THR A 1 367 ? 103.454 121.953 137.152 1.00 128.88 ? 948 THR A O   1 
ATOM 2444 C CB  . THR A 1 367 ? 104.672 120.258 134.334 1.00 128.88 ? 948 THR A CB  1 
ATOM 2445 O OG1 . THR A 1 367 ? 105.205 121.582 134.200 1.00 128.88 ? 948 THR A OG1 1 
ATOM 2446 C CG2 . THR A 1 367 ? 104.028 119.838 133.018 1.00 128.88 ? 948 THR A CG2 1 
ATOM 2447 N N   . ARG A 1 368 ? 105.298 120.677 137.222 1.00 119.49 ? 949 ARG A N   1 
ATOM 2448 C CA  . ARG A 1 368 ? 105.934 121.367 138.340 1.00 119.49 ? 949 ARG A CA  1 
ATOM 2449 C C   . ARG A 1 368 ? 107.404 121.572 137.976 1.00 119.49 ? 949 ARG A C   1 
ATOM 2450 O O   . ARG A 1 368 ? 107.796 121.391 136.821 1.00 119.49 ? 949 ARG A O   1 
ATOM 2451 C CB  . ARG A 1 368 ? 105.766 120.570 139.649 1.00 119.49 ? 949 ARG A CB  1 
ATOM 2452 C CG  . ARG A 1 368 ? 104.330 120.306 140.115 1.00 119.49 ? 949 ARG A CG  1 
ATOM 2453 C CD  . ARG A 1 368 ? 103.562 121.573 140.511 1.00 119.49 ? 949 ARG A CD  1 
ATOM 2454 N NE  . ARG A 1 368 ? 104.403 122.615 141.092 1.00 119.49 ? 949 ARG A NE  1 
ATOM 2455 C CZ  . ARG A 1 368 ? 104.772 122.660 142.365 1.00 119.49 ? 949 ARG A CZ  1 
ATOM 2456 N NH1 . ARG A 1 368 ? 104.390 121.735 143.231 1.00 119.49 ? 949 ARG A NH1 1 
ATOM 2457 N NH2 . ARG A 1 368 ? 105.544 123.660 142.782 1.00 119.49 ? 949 ARG A NH2 1 
ATOM 2458 N N   . LYS A 1 369 ? 108.212 121.959 138.962 1.00 115.05 ? 950 LYS A N   1 
ATOM 2459 C CA  . LYS A 1 369 ? 109.661 122.016 138.809 1.00 115.05 ? 950 LYS A CA  1 
ATOM 2460 C C   . LYS A 1 369 ? 110.245 120.778 139.471 1.00 115.05 ? 950 LYS A C   1 
ATOM 2461 O O   . LYS A 1 369 ? 109.972 120.513 140.646 1.00 115.05 ? 950 LYS A O   1 
ATOM 2462 C CB  . LYS A 1 369 ? 110.242 123.293 139.421 1.00 115.05 ? 950 LYS A CB  1 
ATOM 2463 C CG  . LYS A 1 369 ? 109.852 124.563 138.680 1.00 115.05 ? 950 LYS A CG  1 
ATOM 2464 C CD  . LYS A 1 369 ? 110.593 125.775 139.223 1.00 115.05 ? 950 LYS A CD  1 
ATOM 2465 C CE  . LYS A 1 369 ? 110.043 126.203 140.572 1.00 115.05 ? 950 LYS A CE  1 
ATOM 2466 N NZ  . LYS A 1 369 ? 110.686 127.454 141.058 1.00 115.05 ? 950 LYS A NZ  1 
ATOM 2467 N N   . SER A 1 370 ? 111.047 120.027 138.720 1.00 104.21 ? 951 SER A N   1 
ATOM 2468 C CA  . SER A 1 370 ? 111.471 118.684 139.117 1.00 104.21 ? 951 SER A CA  1 
ATOM 2469 C C   . SER A 1 370 ? 112.644 118.658 140.095 1.00 104.21 ? 951 SER A C   1 
ATOM 2470 O O   . SER A 1 370 ? 113.201 117.548 140.179 1.00 104.21 ? 951 SER A O   1 
ATOM 2471 C CB  . SER A 1 370 ? 111.825 117.868 137.873 1.00 104.21 ? 951 SER A CB  1 
ATOM 2472 O OG  . SER A 1 370 ? 110.655 117.436 137.201 1.00 104.21 ? 951 SER A OG  1 
ATOM 2473 N N   . VAL A 1 371 ? 113.053 119.766 140.728 1.00 104.33 ? 952 VAL A N   1 
ATOM 2474 C CA  . VAL A 1 371 ? 113.970 119.829 141.876 1.00 104.33 ? 952 VAL A CA  1 
ATOM 2475 C C   . VAL A 1 371 ? 115.401 119.389 141.556 1.00 104.33 ? 952 VAL A C   1 
ATOM 2476 O O   . VAL A 1 371 ? 116.347 120.148 141.797 1.00 104.33 ? 952 VAL A O   1 
ATOM 2477 C CB  . VAL A 1 371 ? 113.409 119.035 143.076 1.00 104.33 ? 952 VAL A CB  1 
ATOM 2478 C CG1 . VAL A 1 371 ? 114.405 119.001 144.227 1.00 104.33 ? 952 VAL A CG1 1 
ATOM 2479 C CG2 . VAL A 1 371 ? 112.101 119.646 143.533 1.00 104.33 ? 952 VAL A CG2 1 
ATOM 2480 N N   . PHE A 1 372 ? 115.577 118.168 141.034 1.00 107.65 ? 953 PHE A N   1 
ATOM 2481 C CA  . PHE A 1 372 ? 116.910 117.623 140.777 1.00 107.65 ? 953 PHE A CA  1 
ATOM 2482 C C   . PHE A 1 372 ? 117.638 118.368 139.662 1.00 107.65 ? 953 PHE A C   1 
ATOM 2483 O O   . PHE A 1 372 ? 118.874 118.408 139.638 1.00 107.65 ? 953 PHE A O   1 
ATOM 2484 C CB  . PHE A 1 372 ? 116.807 116.138 140.426 1.00 107.65 ? 953 PHE A CB  1 
ATOM 2485 C CG  . PHE A 1 372 ? 116.691 115.240 141.620 1.00 107.65 ? 953 PHE A CG  1 
ATOM 2486 C CD1 . PHE A 1 372 ? 117.804 114.956 142.399 1.00 107.65 ? 953 PHE A CD1 1 
ATOM 2487 C CD2 . PHE A 1 372 ? 115.470 114.676 141.964 1.00 107.65 ? 953 PHE A CD2 1 
ATOM 2488 C CE1 . PHE A 1 372 ? 117.704 114.125 143.504 1.00 107.65 ? 953 PHE A CE1 1 
ATOM 2489 C CE2 . PHE A 1 372 ? 115.360 113.844 143.067 1.00 107.65 ? 953 PHE A CE2 1 
ATOM 2490 C CZ  . PHE A 1 372 ? 116.479 113.569 143.837 1.00 107.65 ? 953 PHE A CZ  1 
ATOM 2491 N N   . ILE A 1 373 ? 116.893 118.965 138.732 1.00 102.91 ? 954 ILE A N   1 
ATOM 2492 C CA  . ILE A 1 373 ? 117.534 119.655 137.617 1.00 102.91 ? 954 ILE A CA  1 
ATOM 2493 C C   . ILE A 1 373 ? 117.941 121.071 138.013 1.00 102.91 ? 954 ILE A C   1 
ATOM 2494 O O   . ILE A 1 373 ? 118.817 121.674 137.382 1.00 102.91 ? 954 ILE A O   1 
ATOM 2495 C CB  . ILE A 1 373 ? 116.618 119.638 136.379 1.00 102.91 ? 954 ILE A CB  1 
ATOM 2496 C CG1 . ILE A 1 373 ? 115.282 120.313 136.677 1.00 102.91 ? 954 ILE A CG1 1 
ATOM 2497 C CG2 . ILE A 1 373 ? 116.398 118.213 135.902 1.00 102.91 ? 954 ILE A CG2 1 
ATOM 2498 C CD1 . ILE A 1 373 ? 114.431 120.502 135.452 1.00 102.91 ? 954 ILE A CD1 1 
ATOM 2499 N N   . THR A 1 374 ? 117.323 121.627 139.060 1.00 99.98  ? 955 THR A N   1 
ATOM 2500 C CA  . THR A 1 374 ? 117.745 122.946 139.520 1.00 99.98  ? 955 THR A CA  1 
ATOM 2501 C C   . THR A 1 374 ? 118.742 122.866 140.672 1.00 99.98  ? 955 THR A C   1 
ATOM 2502 O O   . THR A 1 374 ? 119.207 123.910 141.146 1.00 99.98  ? 955 THR A O   1 
ATOM 2503 C CB  . THR A 1 374 ? 116.531 123.803 139.907 1.00 99.98  ? 955 THR A CB  1 
ATOM 2504 O OG1 . THR A 1 374 ? 116.926 125.177 140.002 1.00 99.98  ? 955 THR A OG1 1 
ATOM 2505 C CG2 . THR A 1 374 ? 115.931 123.367 141.233 1.00 99.98  ? 955 THR A CG2 1 
ATOM 2506 N N   . ARG A 1 375 ? 119.090 121.655 141.122 1.00 105.01 ? 956 ARG A N   1 
ATOM 2507 C CA  . ARG A 1 375 ? 120.203 121.498 142.056 1.00 105.01 ? 956 ARG A CA  1 
ATOM 2508 C C   . ARG A 1 375 ? 121.533 121.815 141.385 1.00 105.01 ? 956 ARG A C   1 
ATOM 2509 O O   . ARG A 1 375 ? 122.466 122.298 142.037 1.00 105.01 ? 956 ARG A O   1 
ATOM 2510 C CB  . ARG A 1 375 ? 120.232 120.079 142.628 1.00 105.01 ? 956 ARG A CB  1 
ATOM 2511 C CG  . ARG A 1 375 ? 119.093 119.739 143.568 1.00 105.01 ? 956 ARG A CG  1 
ATOM 2512 C CD  . ARG A 1 375 ? 119.279 120.393 144.926 1.00 105.01 ? 956 ARG A CD  1 
ATOM 2513 N NE  . ARG A 1 375 ? 118.189 120.070 145.839 1.00 105.01 ? 956 ARG A NE  1 
ATOM 2514 C CZ  . ARG A 1 375 ? 118.147 118.986 146.602 1.00 105.01 ? 956 ARG A CZ  1 
ATOM 2515 N NH1 . ARG A 1 375 ? 119.124 118.094 146.591 1.00 105.01 ? 956 ARG A NH1 1 
ATOM 2516 N NH2 . ARG A 1 375 ? 117.099 118.793 147.398 1.00 105.01 ? 956 ARG A NH2 1 
ATOM 2517 N N   . LYS A 1 376 ? 121.637 121.554 140.082 1.00 99.35  ? 957 LYS A N   1 
ATOM 2518 C CA  . LYS A 1 376 ? 122.856 121.820 139.329 1.00 99.35  ? 957 LYS A CA  1 
ATOM 2519 C C   . LYS A 1 376 ? 122.852 123.234 138.758 1.00 99.35  ? 957 LYS A C   1 
ATOM 2520 O O   . LYS A 1 376 ? 123.047 123.430 137.554 1.00 99.35  ? 957 LYS A O   1 
ATOM 2521 C CB  . LYS A 1 376 ? 123.016 120.784 138.215 1.00 99.35  ? 957 LYS A CB  1 
ATOM 2522 C CG  . LYS A 1 376 ? 122.788 119.356 138.690 1.00 99.35  ? 957 LYS A CG  1 
ATOM 2523 C CD  . LYS A 1 376 ? 121.957 118.554 137.703 1.00 99.35  ? 957 LYS A CD  1 
ATOM 2524 C CE  . LYS A 1 376 ? 122.679 118.385 136.383 1.00 99.35  ? 957 LYS A CE  1 
ATOM 2525 N NZ  . LYS A 1 376 ? 121.790 117.815 135.338 1.00 99.35  ? 957 LYS A NZ  1 
ATOM 2526 N N   . LEU A 1 377 ? 122.627 124.218 139.623 1.00 101.81 ? 958 LEU A N   1 
ATOM 2527 C CA  . LEU A 1 377 ? 122.620 125.640 139.300 1.00 101.81 ? 958 LEU A CA  1 
ATOM 2528 C C   . LEU A 1 377 ? 123.423 126.391 140.359 1.00 101.81 ? 958 LEU A C   1 
ATOM 2529 O O   . LEU A 1 377 ? 122.948 127.333 140.999 1.00 101.81 ? 958 LEU A O   1 
ATOM 2530 C CB  . LEU A 1 377 ? 121.180 126.144 139.175 1.00 101.81 ? 958 LEU A CB  1 
ATOM 2531 C CG  . LEU A 1 377 ? 120.870 127.470 138.465 1.00 101.81 ? 958 LEU A CG  1 
ATOM 2532 C CD1 . LEU A 1 377 ? 121.633 127.567 137.160 1.00 101.81 ? 958 LEU A CD1 1 
ATOM 2533 C CD2 . LEU A 1 377 ? 119.376 127.618 138.229 1.00 101.81 ? 958 LEU A CD2 1 
ATOM 2534 N N   . THR A 1 378 ? 124.642 125.901 140.609 1.00 108.47 ? 959 THR A N   1 
ATOM 2535 C CA  . THR A 1 378 ? 125.526 126.454 141.630 1.00 108.47 ? 959 THR A CA  1 
ATOM 2536 C C   . THR A 1 378 ? 125.959 127.879 141.298 1.00 108.47 ? 959 THR A C   1 
ATOM 2537 O O   . THR A 1 378 ? 126.030 128.745 142.177 1.00 108.47 ? 959 THR A O   1 
ATOM 2538 C CB  . THR A 1 378 ? 126.750 125.549 141.797 1.00 108.47 ? 959 THR A CB  1 
ATOM 2539 O OG1 . THR A 1 378 ? 127.449 125.453 140.549 1.00 108.47 ? 959 THR A OG1 1 
ATOM 2540 C CG2 . THR A 1 378 ? 126.326 124.158 142.242 1.00 108.47 ? 959 THR A CG2 1 
ATOM 2541 N N   . VAL A 1 379 ? 126.247 128.134 140.025 1.00 110.15 ? 960 VAL A N   1 
ATOM 2542 C CA  . VAL A 1 379 ? 126.487 129.492 139.555 1.00 110.15 ? 960 VAL A CA  1 
ATOM 2543 C C   . VAL A 1 379 ? 125.131 130.151 139.333 1.00 110.15 ? 960 VAL A C   1 
ATOM 2544 O O   . VAL A 1 379 ? 124.101 129.468 139.284 1.00 110.15 ? 960 VAL A O   1 
ATOM 2545 C CB  . VAL A 1 379 ? 127.354 129.502 138.283 1.00 110.15 ? 960 VAL A CB  1 
ATOM 2546 C CG1 . VAL A 1 379 ? 128.645 128.732 138.515 1.00 110.15 ? 960 VAL A CG1 1 
ATOM 2547 C CG2 . VAL A 1 379 ? 126.591 128.920 137.107 1.00 110.15 ? 960 VAL A CG2 1 
ATOM 2548 N N   . SER A 1 380 ? 125.111 131.475 139.202 1.00 107.99 ? 961 SER A N   1 
ATOM 2549 C CA  . SER A 1 380 ? 123.839 132.183 139.219 1.00 107.99 ? 961 SER A CA  1 
ATOM 2550 C C   . SER A 1 380 ? 123.177 132.173 137.842 1.00 107.99 ? 961 SER A C   1 
ATOM 2551 O O   . SER A 1 380 ? 123.599 131.476 136.915 1.00 107.99 ? 961 SER A O   1 
ATOM 2552 C CB  . SER A 1 380 ? 124.023 133.625 139.696 1.00 107.99 ? 961 SER A CB  1 
ATOM 2553 O OG  . SER A 1 380 ? 124.342 134.490 138.621 1.00 107.99 ? 961 SER A OG  1 
ATOM 2554 N N   . VAL A 1 381 ? 122.113 132.972 137.728 1.00 99.07  ? 962 VAL A N   1 
ATOM 2555 C CA  . VAL A 1 381 ? 121.274 132.978 136.532 1.00 99.07  ? 962 VAL A CA  1 
ATOM 2556 C C   . VAL A 1 381 ? 121.969 133.681 135.364 1.00 99.07  ? 962 VAL A C   1 
ATOM 2557 O O   . VAL A 1 381 ? 121.725 133.353 134.196 1.00 99.07  ? 962 VAL A O   1 
ATOM 2558 C CB  . VAL A 1 381 ? 119.897 133.594 136.896 1.00 99.07  ? 962 VAL A CB  1 
ATOM 2559 C CG1 . VAL A 1 381 ? 120.010 135.058 137.299 1.00 99.07  ? 962 VAL A CG1 1 
ATOM 2560 C CG2 . VAL A 1 381 ? 118.874 133.421 135.781 1.00 99.07  ? 962 VAL A CG2 1 
ATOM 2561 N N   . GLY A 1 382 ? 122.887 134.607 135.651 1.00 100.46 ? 963 GLY A N   1 
ATOM 2562 C CA  . GLY A 1 382 ? 123.464 135.412 134.585 1.00 100.46 ? 963 GLY A CA  1 
ATOM 2563 C C   . GLY A 1 382 ? 124.541 134.684 133.805 1.00 100.46 ? 963 GLY A C   1 
ATOM 2564 O O   . GLY A 1 382 ? 124.619 134.793 132.580 1.00 100.46 ? 963 GLY A O   1 
ATOM 2565 N N   . GLU A 1 383 ? 125.377 133.915 134.502 1.00 101.59 ? 964 GLU A N   1 
ATOM 2566 C CA  . GLU A 1 383 ? 126.542 133.325 133.853 1.00 101.59 ? 964 GLU A CA  1 
ATOM 2567 C C   . GLU A 1 383 ? 126.228 132.034 133.114 1.00 101.59 ? 964 GLU A C   1 
ATOM 2568 O O   . GLU A 1 383 ? 127.116 131.492 132.447 1.00 101.59 ? 964 GLU A O   1 
ATOM 2569 C CB  . GLU A 1 383 ? 127.653 133.092 134.876 1.00 101.59 ? 964 GLU A CB  1 
ATOM 2570 C CG  . GLU A 1 383 ? 127.183 132.590 136.224 1.00 101.59 ? 964 GLU A CG  1 
ATOM 2571 C CD  . GLU A 1 383 ? 127.042 133.696 137.250 1.00 101.59 ? 964 GLU A CD  1 
ATOM 2572 O OE1 . GLU A 1 383 ? 126.406 134.724 136.933 1.00 101.59 ? 964 GLU A OE1 1 
ATOM 2573 O OE2 . GLU A 1 383 ? 127.562 133.540 138.374 1.00 101.59 ? 964 GLU A OE2 1 
ATOM 2574 N N   . ILE A 1 384 ? 125.004 131.519 133.231 1.00 96.83  ? 965 ILE A N   1 
ATOM 2575 C CA  . ILE A 1 384 ? 124.622 130.329 132.474 1.00 96.83  ? 965 ILE A CA  1 
ATOM 2576 C C   . ILE A 1 384 ? 124.462 130.669 130.995 1.00 96.83  ? 965 ILE A C   1 
ATOM 2577 O O   . ILE A 1 384 ? 125.006 129.986 130.119 1.00 96.83  ? 965 ILE A O   1 
ATOM 2578 C CB  . ILE A 1 384 ? 123.343 129.712 133.073 1.00 96.83  ? 965 ILE A CB  1 
ATOM 2579 C CG1 . ILE A 1 384 ? 123.690 128.909 134.327 1.00 96.83  ? 965 ILE A CG1 1 
ATOM 2580 C CG2 . ILE A 1 384 ? 122.621 128.818 132.079 1.00 96.83  ? 965 ILE A CG2 1 
ATOM 2581 C CD1 . ILE A 1 384 ? 124.650 127.764 134.076 1.00 96.83  ? 965 ILE A CD1 1 
ATOM 2582 N N   . VAL A 1 385 ? 123.758 131.764 130.699 1.00 97.07  ? 966 VAL A N   1 
ATOM 2583 C CA  . VAL A 1 385 ? 123.446 132.094 129.310 1.00 97.07  ? 966 VAL A CA  1 
ATOM 2584 C C   . VAL A 1 385 ? 124.635 132.771 128.636 1.00 97.07  ? 966 VAL A C   1 
ATOM 2585 O O   . VAL A 1 385 ? 124.698 132.871 127.405 1.00 97.07  ? 966 VAL A O   1 
ATOM 2586 C CB  . VAL A 1 385 ? 122.179 132.965 129.236 1.00 97.07  ? 966 VAL A CB  1 
ATOM 2587 C CG1 . VAL A 1 385 ? 120.987 132.204 129.790 1.00 97.07  ? 966 VAL A CG1 1 
ATOM 2588 C CG2 . VAL A 1 385 ? 122.377 134.259 129.992 1.00 97.07  ? 966 VAL A CG2 1 
ATOM 2589 N N   . ASN A 1 386 ? 125.592 133.253 129.430 1.00 96.26  ? 967 ASN A N   1 
ATOM 2590 C CA  . ASN A 1 386 ? 126.813 133.803 128.855 1.00 96.26  ? 967 ASN A CA  1 
ATOM 2591 C C   . ASN A 1 386 ? 127.825 132.693 128.600 1.00 96.26  ? 967 ASN A C   1 
ATOM 2592 O O   . ASN A 1 386 ? 128.370 132.591 127.495 1.00 96.26  ? 967 ASN A O   1 
ATOM 2593 C CB  . ASN A 1 386 ? 127.384 134.872 129.798 1.00 96.26  ? 967 ASN A CB  1 
ATOM 2594 C CG  . ASN A 1 386 ? 128.546 135.677 129.195 1.00 96.26  ? 967 ASN A CG  1 
ATOM 2595 O OD1 . ASN A 1 386 ? 128.985 135.460 128.065 1.00 96.26  ? 967 ASN A OD1 1 
ATOM 2596 N ND2 . ASN A 1 386 ? 129.047 136.626 129.978 1.00 96.26  ? 967 ASN A ND2 1 
ATOM 2597 N N   . GLY A 1 387 ? 128.081 131.859 129.602 1.00 98.46  ? 968 GLY A N   1 
ATOM 2598 C CA  . GLY A 1 387 ? 129.066 130.803 129.496 1.00 98.46  ? 968 GLY A CA  1 
ATOM 2599 C C   . GLY A 1 387 ? 130.363 131.197 130.168 1.00 98.46  ? 968 GLY A C   1 
ATOM 2600 O O   . GLY A 1 387 ? 131.185 131.903 129.577 1.00 98.46  ? 968 GLY A O   1 
ATOM 2601 N N   . GLY A 1 388 ? 130.561 130.744 131.402 1.00 95.26  ? 969 GLY A N   1 
ATOM 2602 C CA  . GLY A 1 388 ? 131.752 131.071 132.145 1.00 95.26  ? 969 GLY A CA  1 
ATOM 2603 C C   . GLY A 1 388 ? 131.627 132.380 132.900 1.00 95.26  ? 969 GLY A C   1 
ATOM 2604 O O   . GLY A 1 388 ? 130.707 132.575 133.699 1.00 95.26  ? 969 GLY A O   1 
ATOM 2605 N N   . PRO A 1 389 ? 132.559 133.308 132.662 1.00 103.82 ? 970 PRO A N   1 
ATOM 2606 C CA  . PRO A 1 389 ? 132.547 134.571 133.411 1.00 103.82 ? 970 PRO A CA  1 
ATOM 2607 C C   . PRO A 1 389 ? 131.648 135.627 132.786 1.00 103.82 ? 970 PRO A C   1 
ATOM 2608 O O   . PRO A 1 389 ? 130.967 135.366 131.790 1.00 103.82 ? 970 PRO A O   1 
ATOM 2609 C CB  . PRO A 1 389 ? 134.019 135.006 133.390 1.00 103.82 ? 970 PRO A CB  1 
ATOM 2610 C CG  . PRO A 1 389 ? 134.710 134.113 132.369 1.00 103.82 ? 970 PRO A CG  1 
ATOM 2611 C CD  . PRO A 1 389 ? 133.676 133.257 131.707 1.00 103.82 ? 970 PRO A CD  1 
ATOM 2612 N N   . LEU A 1 390 ? 131.651 136.831 133.369 1.00 100.04 ? 971 LEU A N   1 
ATOM 2613 C CA  . LEU A 1 390 ? 130.892 137.994 132.913 1.00 100.04 ? 971 LEU A CA  1 
ATOM 2614 C C   . LEU A 1 390 ? 131.840 139.161 132.698 1.00 100.04 ? 971 LEU A C   1 
ATOM 2615 O O   . LEU A 1 390 ? 132.810 139.304 133.456 1.00 100.04 ? 971 LEU A O   1 
ATOM 2616 C CB  . LEU A 1 390 ? 129.809 138.414 133.913 1.00 100.04 ? 971 LEU A CB  1 
ATOM 2617 C CG  . LEU A 1 390 ? 128.825 137.416 134.507 1.00 100.04 ? 971 LEU A CG  1 
ATOM 2618 C CD1 . LEU A 1 390 ? 127.685 138.178 135.133 1.00 100.04 ? 971 LEU A CD1 1 
ATOM 2619 C CD2 . LEU A 1 390 ? 128.267 136.575 133.385 1.00 100.04 ? 971 LEU A CD2 1 
ATOM 2620 N N   . PRO A 1 391 ? 131.598 139.999 131.694 1.00 105.98 ? 972 PRO A N   1 
ATOM 2621 C CA  . PRO A 1 391 ? 132.326 141.266 131.595 1.00 105.98 ? 972 PRO A CA  1 
ATOM 2622 C C   . PRO A 1 391 ? 131.747 142.284 132.560 1.00 105.98 ? 972 PRO A C   1 
ATOM 2623 O O   . PRO A 1 391 ? 130.551 142.602 132.492 1.00 105.98 ? 972 PRO A O   1 
ATOM 2624 C CB  . PRO A 1 391 ? 132.106 141.694 130.134 1.00 105.98 ? 972 PRO A CB  1 
ATOM 2625 C CG  . PRO A 1 391 ? 131.407 140.539 129.465 1.00 105.98 ? 972 PRO A CG  1 
ATOM 2626 C CD  . PRO A 1 391 ? 130.712 139.787 130.540 1.00 105.98 ? 972 PRO A CD  1 
ATOM 2627 N N   . PRO A 1 392 ? 132.558 142.817 133.480 1.00 123.11 ? 973 PRO A N   1 
ATOM 2628 C CA  . PRO A 1 392 ? 132.003 143.691 134.524 1.00 123.11 ? 973 PRO A CA  1 
ATOM 2629 C C   . PRO A 1 392 ? 132.003 145.185 134.215 1.00 123.11 ? 973 PRO A C   1 
ATOM 2630 O O   . PRO A 1 392 ? 132.920 145.718 133.579 1.00 123.11 ? 973 PRO A O   1 
ATOM 2631 C CB  . PRO A 1 392 ? 132.890 143.367 135.734 1.00 123.11 ? 973 PRO A CB  1 
ATOM 2632 C CG  . PRO A 1 392 ? 134.198 142.820 135.142 1.00 123.11 ? 973 PRO A CG  1 
ATOM 2633 C CD  . PRO A 1 392 ? 134.011 142.643 133.649 1.00 123.11 ? 973 PRO A CD  1 
ATOM 2634 N N   . VAL A 1 393 ? 130.966 145.854 134.727 1.00 131.57 ? 974 VAL A N   1 
ATOM 2635 C CA  . VAL A 1 393 ? 130.676 147.292 134.627 1.00 131.57 ? 974 VAL A CA  1 
ATOM 2636 C C   . VAL A 1 393 ? 130.699 147.790 133.179 1.00 131.57 ? 974 VAL A C   1 
ATOM 2637 O O   . VAL A 1 393 ? 131.716 148.347 132.735 1.00 131.57 ? 974 VAL A O   1 
ATOM 2638 C CB  . VAL A 1 393 ? 131.623 148.114 135.527 1.00 131.57 ? 974 VAL A CB  1 
ATOM 2639 C CG1 . VAL A 1 393 ? 131.125 149.561 135.692 1.00 131.57 ? 974 VAL A CG1 1 
ATOM 2640 C CG2 . VAL A 1 393 ? 131.763 147.466 136.901 1.00 131.57 ? 974 VAL A CG2 1 
ATOM 2641 N N   . PRO A 1 394 ? 129.665 147.535 132.373 1.00 126.17 ? 975 PRO A N   1 
ATOM 2642 C CA  . PRO A 1 394 ? 129.583 148.214 131.070 1.00 126.17 ? 975 PRO A CA  1 
ATOM 2643 C C   . PRO A 1 394 ? 128.840 149.540 131.178 1.00 126.17 ? 975 PRO A C   1 
ATOM 2644 O O   . PRO A 1 394 ? 127.727 149.615 131.705 1.00 126.17 ? 975 PRO A O   1 
ATOM 2645 C CB  . PRO A 1 394 ? 128.839 147.202 130.193 1.00 126.17 ? 975 PRO A CB  1 
ATOM 2646 C CG  . PRO A 1 394 ? 128.017 146.388 131.145 1.00 126.17 ? 975 PRO A CG  1 
ATOM 2647 C CD  . PRO A 1 394 ? 128.579 146.549 132.539 1.00 126.17 ? 975 PRO A CD  1 
ATOM 2648 N N   . ARG A 1 395 ? 129.467 150.597 130.673 1.00 137.78 ? 976 ARG A N   1 
ATOM 2649 C CA  . ARG A 1 395 ? 128.856 151.921 130.723 1.00 137.78 ? 976 ARG A CA  1 
ATOM 2650 C C   . ARG A 1 395 ? 129.146 152.709 129.451 1.00 137.78 ? 976 ARG A C   1 
ATOM 2651 O O   . ARG A 1 395 ? 130.277 152.730 128.966 1.00 137.78 ? 976 ARG A O   1 
ATOM 2652 C CB  . ARG A 1 395 ? 129.350 152.696 131.947 1.00 137.78 ? 976 ARG A CB  1 
ATOM 2653 C CG  . ARG A 1 395 ? 128.478 152.535 133.186 1.00 137.78 ? 976 ARG A CG  1 
ATOM 2654 C CD  . ARG A 1 395 ? 127.040 152.983 132.952 1.00 137.78 ? 976 ARG A CD  1 
ATOM 2655 N NE  . ARG A 1 395 ? 126.939 154.402 132.627 1.00 137.78 ? 976 ARG A NE  1 
ATOM 2656 C CZ  . ARG A 1 395 ? 126.527 154.878 131.460 1.00 137.78 ? 976 ARG A CZ  1 
ATOM 2657 N NH1 . ARG A 1 395 ? 126.156 154.075 130.477 1.00 137.78 ? 976 ARG A NH1 1 
ATOM 2658 N NH2 . ARG A 1 395 ? 126.481 156.195 131.277 1.00 137.78 ? 976 ARG A NH2 1 
ATOM 2659 N N   . THR B 2 5   ? 119.006 124.555 58.260  1.00 200.47 ? 5   THR B N   1 
ATOM 2660 C CA  . THR B 2 5   ? 118.484 123.304 58.792  1.00 200.47 ? 5   THR B CA  1 
ATOM 2661 C C   . THR B 2 5   ? 117.218 123.542 59.612  1.00 200.47 ? 5   THR B C   1 
ATOM 2662 O O   . THR B 2 5   ? 116.637 122.608 60.166  1.00 200.47 ? 5   THR B O   1 
ATOM 2663 C CB  . THR B 2 5   ? 119.519 122.581 59.668  1.00 200.47 ? 5   THR B CB  1 
ATOM 2664 O OG1 . THR B 2 5   ? 119.707 123.311 60.885  1.00 200.47 ? 5   THR B OG1 1 
ATOM 2665 C CG2 . THR B 2 5   ? 120.849 122.472 58.934  1.00 200.47 ? 5   THR B CG2 1 
ATOM 2666 N N   . ILE B 2 6   ? 116.793 124.805 59.664  1.00 199.24 ? 6   ILE B N   1 
ATOM 2667 C CA  . ILE B 2 6   ? 115.711 125.206 60.561  1.00 199.24 ? 6   ILE B CA  1 
ATOM 2668 C C   . ILE B 2 6   ? 114.363 124.775 59.993  1.00 199.24 ? 6   ILE B C   1 
ATOM 2669 O O   . ILE B 2 6   ? 113.428 124.444 60.741  1.00 199.24 ? 6   ILE B O   1 
ATOM 2670 C CB  . ILE B 2 6   ? 115.777 126.727 60.808  1.00 199.24 ? 6   ILE B CB  1 
ATOM 2671 C CG1 . ILE B 2 6   ? 117.222 127.182 61.050  1.00 199.24 ? 6   ILE B CG1 1 
ATOM 2672 C CG2 . ILE B 2 6   ? 114.935 127.124 62.004  1.00 199.24 ? 6   ILE B CG2 1 
ATOM 2673 C CD1 . ILE B 2 6   ? 117.880 126.603 62.310  1.00 199.24 ? 6   ILE B CD1 1 
ATOM 2674 N N   . ASN B 2 7   ? 114.264 124.731 58.658  1.00 202.78 ? 7   ASN B N   1 
ATOM 2675 C CA  . ASN B 2 7   ? 112.990 124.493 57.982  1.00 202.78 ? 7   ASN B CA  1 
ATOM 2676 C C   . ASN B 2 7   ? 112.503 123.064 58.181  1.00 202.78 ? 7   ASN B C   1 
ATOM 2677 O O   . ASN B 2 7   ? 111.294 122.814 58.223  1.00 202.78 ? 7   ASN B O   1 
ATOM 2678 C CB  . ASN B 2 7   ? 113.126 124.799 56.492  1.00 202.78 ? 7   ASN B CB  1 
ATOM 2679 C CG  . ASN B 2 7   ? 113.290 126.273 56.216  1.00 202.78 ? 7   ASN B CG  1 
ATOM 2680 O OD1 . ASN B 2 7   ? 112.619 127.103 56.827  1.00 202.78 ? 7   ASN B OD1 1 
ATOM 2681 N ND2 . ASN B 2 7   ? 114.183 126.610 55.292  1.00 202.78 ? 7   ASN B ND2 1 
ATOM 2682 N N   . GLN B 2 8   ? 113.434 122.119 58.328  1.00 203.87 ? 8   GLN B N   1 
ATOM 2683 C CA  . GLN B 2 8   ? 113.058 120.744 58.639  1.00 203.87 ? 8   GLN B CA  1 
ATOM 2684 C C   . GLN B 2 8   ? 112.487 120.628 60.048  1.00 203.87 ? 8   GLN B C   1 
ATOM 2685 O O   . GLN B 2 8   ? 111.544 119.858 60.274  1.00 203.87 ? 8   GLN B O   1 
ATOM 2686 C CB  . GLN B 2 8   ? 114.251 119.802 58.445  1.00 203.87 ? 8   GLN B CB  1 
ATOM 2687 C CG  . GLN B 2 8   ? 114.726 119.636 56.992  1.00 203.87 ? 8   GLN B CG  1 
ATOM 2688 C CD  . GLN B 2 8   ? 115.630 120.749 56.517  1.00 203.87 ? 8   GLN B CD  1 
ATOM 2689 O OE1 . GLN B 2 8   ? 116.175 121.491 57.322  1.00 203.87 ? 8   GLN B OE1 1 
ATOM 2690 N NE2 . GLN B 2 8   ? 115.785 120.877 55.204  1.00 203.87 ? 8   GLN B NE2 1 
ATOM 2691 N N   . TYR B 2 9   ? 113.026 121.402 60.999  1.00 203.55 ? 9   TYR B N   1 
ATOM 2692 C CA  . TYR B 2 9   ? 112.460 121.440 62.347  1.00 203.55 ? 9   TYR B CA  1 
ATOM 2693 C C   . TYR B 2 9   ? 111.069 122.067 62.354  1.00 203.55 ? 9   TYR B C   1 
ATOM 2694 O O   . TYR B 2 9   ? 110.167 121.582 63.050  1.00 203.55 ? 9   TYR B O   1 
ATOM 2695 C CB  . TYR B 2 9   ? 113.381 122.179 63.326  1.00 203.55 ? 9   TYR B CB  1 
ATOM 2696 C CG  . TYR B 2 9   ? 114.863 121.868 63.258  1.00 203.55 ? 9   TYR B CG  1 
ATOM 2697 C CD1 . TYR B 2 9   ? 115.323 120.556 63.169  1.00 203.55 ? 9   TYR B CD1 1 
ATOM 2698 C CD2 . TYR B 2 9   ? 115.804 122.888 63.354  1.00 203.55 ? 9   TYR B CD2 1 
ATOM 2699 C CE1 . TYR B 2 9   ? 116.681 120.274 63.128  1.00 203.55 ? 9   TYR B CE1 1 
ATOM 2700 C CE2 . TYR B 2 9   ? 117.163 122.619 63.320  1.00 203.55 ? 9   TYR B CE2 1 
ATOM 2701 C CZ  . TYR B 2 9   ? 117.593 121.312 63.203  1.00 203.55 ? 9   TYR B CZ  1 
ATOM 2702 O OH  . TYR B 2 9   ? 118.941 121.039 63.167  1.00 203.55 ? 9   TYR B OH  1 
ATOM 2703 N N   . LEU B 2 10  ? 110.873 123.139 61.570  1.00 198.62 ? 10  LEU B N   1 
ATOM 2704 C CA  . LEU B 2 10  ? 109.537 123.739 61.470  1.00 198.62 ? 10  LEU B CA  1 
ATOM 2705 C C   . LEU B 2 10  ? 108.542 122.813 60.778  1.00 198.62 ? 10  LEU B C   1 
ATOM 2706 O O   . LEU B 2 10  ? 107.367 122.766 61.161  1.00 198.62 ? 10  LEU B O   1 
ATOM 2707 C CB  . LEU B 2 10  ? 109.567 125.097 60.765  1.00 198.62 ? 10  LEU B CB  1 
ATOM 2708 C CG  . LEU B 2 10  ? 109.902 126.385 61.533  1.00 198.62 ? 10  LEU B CG  1 
ATOM 2709 C CD1 . LEU B 2 10  ? 108.819 126.611 62.578  1.00 198.62 ? 10  LEU B CD1 1 
ATOM 2710 C CD2 . LEU B 2 10  ? 111.257 126.444 62.184  1.00 198.62 ? 10  LEU B CD2 1 
ATOM 2711 N N   . GLN B 2 11  ? 109.003 122.043 59.789  1.00 197.55 ? 11  GLN B N   1 
ATOM 2712 C CA  . GLN B 2 11  ? 108.139 121.067 59.129  1.00 197.55 ? 11  GLN B CA  1 
ATOM 2713 C C   . GLN B 2 11  ? 107.756 119.932 60.074  1.00 197.55 ? 11  GLN B C   1 
ATOM 2714 O O   . GLN B 2 11  ? 106.605 119.478 60.081  1.00 197.55 ? 11  GLN B O   1 
ATOM 2715 C CB  . GLN B 2 11  ? 108.831 120.520 57.879  1.00 197.55 ? 11  GLN B CB  1 
ATOM 2716 C CG  . GLN B 2 11  ? 108.724 121.390 56.623  1.00 197.55 ? 11  GLN B CG  1 
ATOM 2717 C CD  . GLN B 2 11  ? 107.294 121.624 56.157  1.00 197.55 ? 11  GLN B CD  1 
ATOM 2718 O OE1 . GLN B 2 11  ? 106.621 122.558 56.596  1.00 197.55 ? 11  GLN B OE1 1 
ATOM 2719 N NE2 . GLN B 2 11  ? 106.822 120.763 55.264  1.00 197.55 ? 11  GLN B NE2 1 
ATOM 2720 N N   . GLN B 2 12  ? 108.698 119.477 60.906  1.00 196.07 ? 12  GLN B N   1 
ATOM 2721 C CA  . GLN B 2 12  ? 108.374 118.348 61.773  1.00 196.07 ? 12  GLN B CA  1 
ATOM 2722 C C   . GLN B 2 12  ? 107.625 118.790 63.029  1.00 196.07 ? 12  GLN B C   1 
ATOM 2723 O O   . GLN B 2 12  ? 107.033 117.951 63.718  1.00 196.07 ? 12  GLN B O   1 
ATOM 2724 C CB  . GLN B 2 12  ? 109.632 117.556 62.140  1.00 196.07 ? 12  GLN B CB  1 
ATOM 2725 C CG  . GLN B 2 12  ? 110.617 118.279 63.023  1.00 196.07 ? 12  GLN B CG  1 
ATOM 2726 C CD  . GLN B 2 12  ? 111.897 117.494 63.245  1.00 196.07 ? 12  GLN B CD  1 
ATOM 2727 O OE1 . GLN B 2 12  ? 112.258 117.186 64.381  1.00 196.07 ? 12  GLN B OE1 1 
ATOM 2728 N NE2 . GLN B 2 12  ? 112.588 117.165 62.160  1.00 196.07 ? 12  GLN B NE2 1 
ATOM 2729 N N   . VAL B 2 13  ? 107.625 120.090 63.358  1.00 192.14 ? 13  VAL B N   1 
ATOM 2730 C CA  . VAL B 2 13  ? 106.746 120.517 64.449  1.00 192.14 ? 13  VAL B CA  1 
ATOM 2731 C C   . VAL B 2 13  ? 105.376 120.902 63.884  1.00 192.14 ? 13  VAL B C   1 
ATOM 2732 O O   . VAL B 2 13  ? 104.360 120.863 64.589  1.00 192.14 ? 13  VAL B O   1 
ATOM 2733 C CB  . VAL B 2 13  ? 107.382 121.658 65.283  1.00 192.14 ? 13  VAL B CB  1 
ATOM 2734 C CG1 . VAL B 2 13  ? 107.544 122.943 64.497  1.00 192.14 ? 13  VAL B CG1 1 
ATOM 2735 C CG2 . VAL B 2 13  ? 106.673 121.882 66.635  1.00 192.14 ? 13  VAL B CG2 1 
ATOM 2736 N N   . TYR B 2 14  ? 105.321 121.243 62.589  1.00 195.15 ? 14  TYR B N   1 
ATOM 2737 C CA  . TYR B 2 14  ? 104.040 121.444 61.919  1.00 195.15 ? 14  TYR B CA  1 
ATOM 2738 C C   . TYR B 2 14  ? 103.294 120.124 61.759  1.00 195.15 ? 14  TYR B C   1 
ATOM 2739 O O   . TYR B 2 14  ? 102.087 120.039 62.025  1.00 195.15 ? 14  TYR B O   1 
ATOM 2740 C CB  . TYR B 2 14  ? 104.285 122.109 60.562  1.00 195.15 ? 14  TYR B CB  1 
ATOM 2741 C CG  . TYR B 2 14  ? 103.049 122.432 59.755  1.00 195.15 ? 14  TYR B CG  1 
ATOM 2742 C CD1 . TYR B 2 14  ? 102.242 123.517 60.089  1.00 195.15 ? 14  TYR B CD1 1 
ATOM 2743 C CD2 . TYR B 2 14  ? 102.710 121.676 58.636  1.00 195.15 ? 14  TYR B CD2 1 
ATOM 2744 C CE1 . TYR B 2 14  ? 101.114 123.826 59.343  1.00 195.15 ? 14  TYR B CE1 1 
ATOM 2745 C CE2 . TYR B 2 14  ? 101.587 121.978 57.881  1.00 195.15 ? 14  TYR B CE2 1 
ATOM 2746 C CZ  . TYR B 2 14  ? 100.793 123.053 58.242  1.00 195.15 ? 14  TYR B CZ  1 
ATOM 2747 O OH  . TYR B 2 14  ? 99.675  123.357 57.499  1.00 195.15 ? 14  TYR B OH  1 
ATOM 2748 N N   . GLU B 2 15  ? 104.012 119.069 61.362  1.00 189.99 ? 15  GLU B N   1 
ATOM 2749 C CA  . GLU B 2 15  ? 103.421 117.738 61.281  1.00 189.99 ? 15  GLU B CA  1 
ATOM 2750 C C   . GLU B 2 15  ? 103.179 117.127 62.658  1.00 189.99 ? 15  GLU B C   1 
ATOM 2751 O O   . GLU B 2 15  ? 102.395 116.179 62.769  1.00 189.99 ? 15  GLU B O   1 
ATOM 2752 C CB  . GLU B 2 15  ? 104.316 116.820 60.441  1.00 189.99 ? 15  GLU B CB  1 
ATOM 2753 C CG  . GLU B 2 15  ? 103.595 115.662 59.744  1.00 189.99 ? 15  GLU B CG  1 
ATOM 2754 C CD  . GLU B 2 15  ? 102.431 116.109 58.873  1.00 189.99 ? 15  GLU B CD  1 
ATOM 2755 O OE1 . GLU B 2 15  ? 102.580 117.098 58.122  1.00 189.99 ? 15  GLU B OE1 1 
ATOM 2756 O OE2 . GLU B 2 15  ? 101.360 115.468 58.941  1.00 189.99 ? 15  GLU B OE2 1 
ATOM 2757 N N   . ALA B 2 16  ? 103.844 117.638 63.699  1.00 186.42 ? 16  ALA B N   1 
ATOM 2758 C CA  . ALA B 2 16  ? 103.550 117.228 65.069  1.00 186.42 ? 16  ALA B CA  1 
ATOM 2759 C C   . ALA B 2 16  ? 102.140 117.639 65.472  1.00 186.42 ? 16  ALA B C   1 
ATOM 2760 O O   . ALA B 2 16  ? 101.406 116.872 66.105  1.00 186.42 ? 16  ALA B O   1 
ATOM 2761 C CB  . ALA B 2 16  ? 104.570 117.842 66.027  1.00 186.42 ? 16  ALA B CB  1 
ATOM 2762 N N   . ILE B 2 17  ? 101.747 118.857 65.104  1.00 184.04 ? 17  ILE B N   1 
ATOM 2763 C CA  . ILE B 2 17  ? 100.435 119.364 65.488  1.00 184.04 ? 17  ILE B CA  1 
ATOM 2764 C C   . ILE B 2 17  ? 99.374  118.858 64.519  1.00 184.04 ? 17  ILE B C   1 
ATOM 2765 O O   . ILE B 2 17  ? 98.246  118.538 64.918  1.00 184.04 ? 17  ILE B O   1 
ATOM 2766 C CB  . ILE B 2 17  ? 100.475 120.904 65.558  1.00 184.04 ? 17  ILE B CB  1 
ATOM 2767 C CG1 . ILE B 2 17  ? 101.612 121.356 66.479  1.00 184.04 ? 17  ILE B CG1 1 
ATOM 2768 C CG2 . ILE B 2 17  ? 99.157  121.480 66.063  1.00 184.04 ? 17  ILE B CG2 1 
ATOM 2769 C CD1 . ILE B 2 17  ? 101.505 120.848 67.899  1.00 184.04 ? 17  ILE B CD1 1 
ATOM 2770 N N   . ASP B 2 18  ? 99.729  118.741 63.235  1.00 191.77 ? 18  ASP B N   1 
ATOM 2771 C CA  . ASP B 2 18  ? 98.734  118.403 62.221  1.00 191.77 ? 18  ASP B CA  1 
ATOM 2772 C C   . ASP B 2 18  ? 98.352  116.925 62.255  1.00 191.77 ? 18  ASP B C   1 
ATOM 2773 O O   . ASP B 2 18  ? 97.181  116.581 62.060  1.00 191.77 ? 18  ASP B O   1 
ATOM 2774 C CB  . ASP B 2 18  ? 99.248  118.791 60.836  1.00 191.77 ? 18  ASP B CB  1 
ATOM 2775 C CG  . ASP B 2 18  ? 99.112  120.273 60.564  1.00 191.77 ? 18  ASP B CG  1 
ATOM 2776 O OD1 . ASP B 2 18  ? 99.053  121.054 61.537  1.00 191.77 ? 18  ASP B OD1 1 
ATOM 2777 O OD2 . ASP B 2 18  ? 99.046  120.656 59.379  1.00 191.77 ? 18  ASP B OD2 1 
ATOM 2778 N N   . SER B 2 19  ? 99.313  116.037 62.502  1.00 190.51 ? 19  SER B N   1 
ATOM 2779 C CA  . SER B 2 19  ? 99.047  114.605 62.442  1.00 190.51 ? 19  SER B CA  1 
ATOM 2780 C C   . SER B 2 19  ? 98.777  113.981 63.805  1.00 190.51 ? 19  SER B C   1 
ATOM 2781 O O   . SER B 2 19  ? 98.585  112.759 63.859  1.00 190.51 ? 19  SER B O   1 
ATOM 2782 C CB  . SER B 2 19  ? 100.211 113.870 61.768  1.00 190.51 ? 19  SER B CB  1 
ATOM 2783 O OG  . SER B 2 19  ? 101.427 114.090 62.459  1.00 190.51 ? 19  SER B OG  1 
ATOM 2784 N N   . ARG B 2 20  ? 98.686  114.810 64.863  1.00 182.57 ? 20  ARG B N   1 
ATOM 2785 C CA  . ARG B 2 20  ? 98.586  114.454 66.303  1.00 182.57 ? 20  ARG B CA  1 
ATOM 2786 C C   . ARG B 2 20  ? 99.458  113.254 66.692  1.00 182.57 ? 20  ARG B C   1 
ATOM 2787 O O   . ARG B 2 20  ? 98.984  112.242 67.212  1.00 182.57 ? 20  ARG B O   1 
ATOM 2788 C CB  . ARG B 2 20  ? 97.125  114.262 66.770  1.00 182.57 ? 20  ARG B CB  1 
ATOM 2789 C CG  . ARG B 2 20  ? 96.155  113.378 65.966  1.00 182.57 ? 20  ARG B CG  1 
ATOM 2790 C CD  . ARG B 2 20  ? 94.709  113.591 66.396  1.00 182.57 ? 20  ARG B CD  1 
ATOM 2791 N NE  . ARG B 2 20  ? 94.351  115.001 66.502  1.00 182.57 ? 20  ARG B NE  1 
ATOM 2792 C CZ  . ARG B 2 20  ? 93.989  115.765 65.481  1.00 182.57 ? 20  ARG B CZ  1 
ATOM 2793 N NH1 . ARG B 2 20  ? 93.902  115.284 64.251  1.00 182.57 ? 20  ARG B NH1 1 
ATOM 2794 N NH2 . ARG B 2 20  ? 93.698  117.044 65.700  1.00 182.57 ? 20  ARG B NH2 1 
ATOM 2795 N N   . ASP B 2 21  ? 100.759 113.386 66.444  1.00 175.86 ? 21  ASP B N   1 
ATOM 2796 C CA  . ASP B 2 21  ? 101.709 112.297 66.611  1.00 175.86 ? 21  ASP B CA  1 
ATOM 2797 C C   . ASP B 2 21  ? 102.406 112.407 67.962  1.00 175.86 ? 21  ASP B C   1 
ATOM 2798 O O   . ASP B 2 21  ? 102.690 113.506 68.447  1.00 175.86 ? 21  ASP B O   1 
ATOM 2799 C CB  . ASP B 2 21  ? 102.749 112.302 65.479  1.00 175.86 ? 21  ASP B CB  1 
ATOM 2800 C CG  . ASP B 2 21  ? 103.627 111.064 65.479  1.00 175.86 ? 21  ASP B CG  1 
ATOM 2801 O OD1 . ASP B 2 21  ? 103.222 110.037 66.064  1.00 175.86 ? 21  ASP B OD1 1 
ATOM 2802 O OD2 . ASP B 2 21  ? 104.729 111.119 64.894  1.00 175.86 ? 21  ASP B OD2 1 
ATOM 2803 N N   . GLY B 2 22  ? 102.677 111.250 68.565  1.00 175.32 ? 22  GLY B N   1 
ATOM 2804 C CA  . GLY B 2 22  ? 103.365 111.190 69.840  1.00 175.32 ? 22  GLY B CA  1 
ATOM 2805 C C   . GLY B 2 22  ? 104.855 110.933 69.726  1.00 175.32 ? 22  GLY B C   1 
ATOM 2806 O O   . GLY B 2 22  ? 105.605 111.181 70.674  1.00 175.32 ? 22  GLY B O   1 
ATOM 2807 N N   . ALA B 2 23  ? 105.300 110.432 68.570  1.00 174.10 ? 23  ALA B N   1 
ATOM 2808 C CA  . ALA B 2 23  ? 106.722 110.177 68.364  1.00 174.10 ? 23  ALA B CA  1 
ATOM 2809 C C   . ALA B 2 23  ? 107.487 111.439 67.986  1.00 174.10 ? 23  ALA B C   1 
ATOM 2810 O O   . ALA B 2 23  ? 108.725 111.425 67.964  1.00 174.10 ? 23  ALA B O   1 
ATOM 2811 C CB  . ALA B 2 23  ? 106.915 109.108 67.287  1.00 174.10 ? 23  ALA B CB  1 
ATOM 2812 N N   . SER B 2 24  ? 106.777 112.534 67.702  1.00 173.19 ? 24  SER B N   1 
ATOM 2813 C CA  . SER B 2 24  ? 107.438 113.777 67.316  1.00 173.19 ? 24  SER B CA  1 
ATOM 2814 C C   . SER B 2 24  ? 108.136 114.431 68.502  1.00 173.19 ? 24  SER B C   1 
ATOM 2815 O O   . SER B 2 24  ? 109.078 115.214 68.321  1.00 173.19 ? 24  SER B O   1 
ATOM 2816 C CB  . SER B 2 24  ? 106.423 114.728 66.695  1.00 173.19 ? 24  SER B CB  1 
ATOM 2817 O OG  . SER B 2 24  ? 105.312 114.913 67.555  1.00 173.19 ? 24  SER B OG  1 
ATOM 2818 N N   . CYS B 2 25  ? 107.685 114.124 69.721  1.00 176.94 ? 25  CYS B N   1 
ATOM 2819 C CA  . CYS B 2 25  ? 108.396 114.479 70.943  1.00 176.94 ? 25  CYS B CA  1 
ATOM 2820 C C   . CYS B 2 25  ? 109.791 113.870 70.994  1.00 176.94 ? 25  CYS B C   1 
ATOM 2821 O O   . CYS B 2 25  ? 110.767 114.573 71.269  1.00 176.94 ? 25  CYS B O   1 
ATOM 2822 C CB  . CYS B 2 25  ? 107.614 114.029 72.172  1.00 176.94 ? 25  CYS B CB  1 
ATOM 2823 S SG  . CYS B 2 25  ? 108.542 114.302 73.679  1.00 176.94 ? 25  CYS B SG  1 
ATOM 2824 N N   . ALA B 2 26  ? 109.893 112.570 70.710  1.00 185.41 ? 26  ALA B N   1 
ATOM 2825 C CA  . ALA B 2 26  ? 111.197 111.915 70.681  1.00 185.41 ? 26  ALA B CA  1 
ATOM 2826 C C   . ALA B 2 26  ? 111.995 112.343 69.457  1.00 185.41 ? 26  ALA B C   1 
ATOM 2827 O O   . ALA B 2 26  ? 113.229 112.276 69.450  1.00 185.41 ? 26  ALA B O   1 
ATOM 2828 C CB  . ALA B 2 26  ? 111.021 110.396 70.711  1.00 185.41 ? 26  ALA B CB  1 
ATOM 2829 N N   . GLU B 2 27  ? 111.300 112.775 68.402  1.00 184.94 ? 27  GLU B N   1 
ATOM 2830 C CA  . GLU B 2 27  ? 111.962 113.332 67.228  1.00 184.94 ? 27  GLU B CA  1 
ATOM 2831 C C   . GLU B 2 27  ? 112.628 114.683 67.490  1.00 184.94 ? 27  GLU B C   1 
ATOM 2832 O O   . GLU B 2 27  ? 113.773 114.875 67.067  1.00 184.94 ? 27  GLU B O   1 
ATOM 2833 C CB  . GLU B 2 27  ? 110.952 113.464 66.085  1.00 184.94 ? 27  GLU B CB  1 
ATOM 2834 C CG  . GLU B 2 27  ? 111.547 113.869 64.749  1.00 184.94 ? 27  GLU B CG  1 
ATOM 2835 C CD  . GLU B 2 27  ? 110.690 113.425 63.581  1.00 184.94 ? 27  GLU B CD  1 
ATOM 2836 O OE1 . GLU B 2 27  ? 111.186 112.640 62.746  1.00 184.94 ? 27  GLU B OE1 1 
ATOM 2837 O OE2 . GLU B 2 27  ? 109.521 113.859 63.499  1.00 184.94 ? 27  GLU B OE2 1 
ATOM 2838 N N   . LEU B 2 28  ? 111.952 115.618 68.167  1.00 179.03 ? 28  LEU B N   1 
ATOM 2839 C CA  . LEU B 2 28  ? 112.480 116.975 68.310  1.00 179.03 ? 28  LEU B CA  1 
ATOM 2840 C C   . LEU B 2 28  ? 112.796 117.347 69.758  1.00 179.03 ? 28  LEU B C   1 
ATOM 2841 O O   . LEU B 2 28  ? 113.898 117.820 70.054  1.00 179.03 ? 28  LEU B O   1 
ATOM 2842 C CB  . LEU B 2 28  ? 111.495 117.987 67.698  1.00 179.03 ? 28  LEU B CB  1 
ATOM 2843 C CG  . LEU B 2 28  ? 111.807 119.484 67.504  1.00 179.03 ? 28  LEU B CG  1 
ATOM 2844 C CD1 . LEU B 2 28  ? 111.017 119.985 66.317  1.00 179.03 ? 28  LEU B CD1 1 
ATOM 2845 C CD2 . LEU B 2 28  ? 111.458 120.372 68.702  1.00 179.03 ? 28  LEU B CD2 1 
ATOM 2846 N N   . VAL B 2 29  ? 111.828 117.163 70.659  1.00 172.74 ? 29  VAL B N   1 
ATOM 2847 C CA  . VAL B 2 29  ? 111.849 117.853 71.948  1.00 172.74 ? 29  VAL B CA  1 
ATOM 2848 C C   . VAL B 2 29  ? 112.795 117.166 72.930  1.00 172.74 ? 29  VAL B C   1 
ATOM 2849 O O   . VAL B 2 29  ? 113.394 117.818 73.795  1.00 172.74 ? 29  VAL B O   1 
ATOM 2850 C CB  . VAL B 2 29  ? 110.396 117.934 72.484  1.00 172.74 ? 29  VAL B CB  1 
ATOM 2851 C CG1 . VAL B 2 29  ? 110.278 118.710 73.802  1.00 172.74 ? 29  VAL B CG1 1 
ATOM 2852 C CG2 . VAL B 2 29  ? 109.483 118.539 71.429  1.00 172.74 ? 29  VAL B CG2 1 
ATOM 2853 N N   . SER B 2 30  ? 113.013 115.867 72.764  1.00 179.15 ? 30  SER B N   1 
ATOM 2854 C CA  . SER B 2 30  ? 113.809 115.099 73.711  1.00 179.15 ? 30  SER B CA  1 
ATOM 2855 C C   . SER B 2 30  ? 115.300 115.358 73.519  1.00 179.15 ? 30  SER B C   1 
ATOM 2856 O O   . SER B 2 30  ? 115.775 115.572 72.401  1.00 179.15 ? 30  SER B O   1 
ATOM 2857 C CB  . SER B 2 30  ? 113.520 113.605 73.564  1.00 179.15 ? 30  SER B CB  1 
ATOM 2858 O OG  . SER B 2 30  ? 114.292 112.842 74.472  1.00 179.15 ? 30  SER B OG  1 
ATOM 2859 N N   . PHE B 2 31  ? 116.034 115.344 74.633  1.00 178.05 ? 31  PHE B N   1 
ATOM 2860 C CA  . PHE B 2 31  ? 117.495 115.444 74.610  1.00 178.05 ? 31  PHE B CA  1 
ATOM 2861 C C   . PHE B 2 31  ? 118.133 114.054 74.556  1.00 178.05 ? 31  PHE B C   1 
ATOM 2862 O O   . PHE B 2 31  ? 118.874 113.633 75.444  1.00 178.05 ? 31  PHE B O   1 
ATOM 2863 C CB  . PHE B 2 31  ? 117.998 116.231 75.816  1.00 178.05 ? 31  PHE B CB  1 
ATOM 2864 C CG  . PHE B 2 31  ? 117.831 117.719 75.693  1.00 178.05 ? 31  PHE B CG  1 
ATOM 2865 C CD1 . PHE B 2 31  ? 118.761 118.474 74.989  1.00 178.05 ? 31  PHE B CD1 1 
ATOM 2866 C CD2 . PHE B 2 31  ? 116.762 118.365 76.294  1.00 178.05 ? 31  PHE B CD2 1 
ATOM 2867 C CE1 . PHE B 2 31  ? 118.621 119.851 74.877  1.00 178.05 ? 31  PHE B CE1 1 
ATOM 2868 C CE2 . PHE B 2 31  ? 116.612 119.741 76.189  1.00 178.05 ? 31  PHE B CE2 1 
ATOM 2869 C CZ  . PHE B 2 31  ? 117.544 120.483 75.479  1.00 178.05 ? 31  PHE B CZ  1 
ATOM 2870 N N   . LYS B 2 32  ? 117.825 113.339 73.479  1.00 182.95 ? 32  LYS B N   1 
ATOM 2871 C CA  . LYS B 2 32  ? 118.427 112.047 73.190  1.00 182.95 ? 32  LYS B CA  1 
ATOM 2872 C C   . LYS B 2 32  ? 118.998 111.952 71.785  1.00 182.95 ? 32  LYS B C   1 
ATOM 2873 O O   . LYS B 2 32  ? 119.666 110.965 71.471  1.00 182.95 ? 32  LYS B O   1 
ATOM 2874 C CB  . LYS B 2 32  ? 117.405 110.915 73.389  1.00 182.95 ? 32  LYS B CB  1 
ATOM 2875 C CG  . LYS B 2 32  ? 117.473 110.232 74.750  1.00 182.95 ? 32  LYS B CG  1 
ATOM 2876 C CD  . LYS B 2 32  ? 116.742 111.023 75.821  1.00 182.95 ? 32  LYS B CD  1 
ATOM 2877 C CE  . LYS B 2 32  ? 116.711 110.276 77.143  1.00 182.95 ? 32  LYS B CE  1 
ATOM 2878 N NZ  . LYS B 2 32  ? 116.041 111.069 78.210  1.00 182.95 ? 32  LYS B NZ  1 
ATOM 2879 N N   . HIS B 2 33  ? 118.755 112.948 70.940  1.00 184.06 ? 33  HIS B N   1 
ATOM 2880 C CA  . HIS B 2 33  ? 119.240 112.976 69.568  1.00 184.06 ? 33  HIS B CA  1 
ATOM 2881 C C   . HIS B 2 33  ? 120.116 114.212 69.389  1.00 184.06 ? 33  HIS B C   1 
ATOM 2882 O O   . HIS B 2 33  ? 120.244 115.005 70.333  1.00 184.06 ? 33  HIS B O   1 
ATOM 2883 C CB  . HIS B 2 33  ? 118.053 112.960 68.594  1.00 184.06 ? 33  HIS B CB  1 
ATOM 2884 C CG  . HIS B 2 33  ? 117.059 114.059 68.820  1.00 184.06 ? 33  HIS B CG  1 
ATOM 2885 N ND1 . HIS B 2 33  ? 117.305 115.375 68.490  1.00 184.06 ? 33  HIS B ND1 1 
ATOM 2886 C CD2 . HIS B 2 33  ? 115.820 114.036 69.364  1.00 184.06 ? 33  HIS B CD2 1 
ATOM 2887 C CE1 . HIS B 2 33  ? 116.256 116.112 68.807  1.00 184.06 ? 33  HIS B CE1 1 
ATOM 2888 N NE2 . HIS B 2 33  ? 115.341 115.323 69.341  1.00 184.06 ? 33  HIS B NE2 1 
ATOM 2889 N N   . PRO B 2 34  ? 120.792 114.371 68.247  1.00 187.11 ? 34  PRO B N   1 
ATOM 2890 C CA  . PRO B 2 34  ? 121.346 115.684 67.895  1.00 187.11 ? 34  PRO B CA  1 
ATOM 2891 C C   . PRO B 2 34  ? 120.269 116.760 67.823  1.00 187.11 ? 34  PRO B C   1 
ATOM 2892 O O   . PRO B 2 34  ? 119.244 116.599 67.156  1.00 187.11 ? 34  PRO B O   1 
ATOM 2893 C CB  . PRO B 2 34  ? 121.972 115.434 66.522  1.00 187.11 ? 34  PRO B CB  1 
ATOM 2894 C CG  . PRO B 2 34  ? 122.412 114.006 66.573  1.00 187.11 ? 34  PRO B CG  1 
ATOM 2895 C CD  . PRO B 2 34  ? 121.562 113.287 67.606  1.00 187.11 ? 34  PRO B CD  1 
ATOM 2896 N N   . HIS B 2 35  ? 120.512 117.864 68.520  1.00 179.87 ? 35  HIS B N   1 
ATOM 2897 C CA  . HIS B 2 35  ? 119.552 118.960 68.585  1.00 179.87 ? 35  HIS B CA  1 
ATOM 2898 C C   . HIS B 2 35  ? 119.595 119.808 67.319  1.00 179.87 ? 35  HIS B C   1 
ATOM 2899 O O   . HIS B 2 35  ? 120.642 120.340 66.952  1.00 179.87 ? 35  HIS B O   1 
ATOM 2900 C CB  . HIS B 2 35  ? 119.821 119.834 69.812  1.00 179.87 ? 35  HIS B CB  1 
ATOM 2901 N N   . PRO B 2 46  ? 115.514 134.063 67.348  1.00 191.44 ? 46  PRO B N   1 
ATOM 2902 C CA  . PRO B 2 46  ? 114.767 133.422 66.261  1.00 191.44 ? 46  PRO B CA  1 
ATOM 2903 C C   . PRO B 2 46  ? 113.302 133.185 66.620  1.00 191.44 ? 46  PRO B C   1 
ATOM 2904 O O   . PRO B 2 46  ? 112.669 132.279 66.080  1.00 191.44 ? 46  PRO B O   1 
ATOM 2905 C CB  . PRO B 2 46  ? 115.503 132.094 66.068  1.00 191.44 ? 46  PRO B CB  1 
ATOM 2906 N N   . GLU B 2 47  ? 112.779 134.003 67.536  1.00 199.53 ? 47  GLU B N   1 
ATOM 2907 C CA  . GLU B 2 47  ? 111.394 133.847 67.972  1.00 199.53 ? 47  GLU B CA  1 
ATOM 2908 C C   . GLU B 2 47  ? 110.424 134.407 66.935  1.00 199.53 ? 47  GLU B C   1 
ATOM 2909 O O   . GLU B 2 47  ? 109.288 133.929 66.805  1.00 199.53 ? 47  GLU B O   1 
ATOM 2910 C CB  . GLU B 2 47  ? 111.212 134.527 69.334  1.00 199.53 ? 47  GLU B CB  1 
ATOM 2911 C CG  . GLU B 2 47  ? 109.881 134.264 70.025  1.00 199.53 ? 47  GLU B CG  1 
ATOM 2912 C CD  . GLU B 2 47  ? 109.905 134.616 71.501  1.00 199.53 ? 47  GLU B CD  1 
ATOM 2913 O OE1 . GLU B 2 47  ? 110.504 133.853 72.288  1.00 199.53 ? 47  GLU B OE1 1 
ATOM 2914 O OE2 . GLU B 2 47  ? 109.323 135.656 71.874  1.00 199.53 ? 47  GLU B OE2 1 
ATOM 2915 N N   . GLU B 2 48  ? 110.866 135.406 66.169  1.00 199.79 ? 48  GLU B N   1 
ATOM 2916 C CA  . GLU B 2 48  ? 110.011 136.109 65.217  1.00 199.79 ? 48  GLU B CA  1 
ATOM 2917 C C   . GLU B 2 48  ? 109.613 135.226 64.039  1.00 199.79 ? 48  GLU B C   1 
ATOM 2918 O O   . GLU B 2 48  ? 108.509 135.372 63.507  1.00 199.79 ? 48  GLU B O   1 
ATOM 2919 C CB  . GLU B 2 48  ? 110.689 137.391 64.702  1.00 199.79 ? 48  GLU B CB  1 
ATOM 2920 C CG  . GLU B 2 48  ? 112.195 137.322 64.372  1.00 199.79 ? 48  GLU B CG  1 
ATOM 2921 C CD  . GLU B 2 48  ? 113.123 137.542 65.570  1.00 199.79 ? 48  GLU B CD  1 
ATOM 2922 O OE1 . GLU B 2 48  ? 114.155 138.221 65.391  1.00 199.79 ? 48  GLU B OE1 1 
ATOM 2923 O OE2 . GLU B 2 48  ? 112.836 137.039 66.677  1.00 199.79 ? 48  GLU B OE2 1 
ATOM 2924 N N   . LYS B 2 49  ? 110.476 134.272 63.670  1.00 195.50 ? 49  LYS B N   1 
ATOM 2925 C CA  . LYS B 2 49  ? 110.163 133.346 62.582  1.00 195.50 ? 49  LYS B CA  1 
ATOM 2926 C C   . LYS B 2 49  ? 109.030 132.395 62.955  1.00 195.50 ? 49  LYS B C   1 
ATOM 2927 O O   . LYS B 2 49  ? 108.083 132.207 62.170  1.00 195.50 ? 49  LYS B O   1 
ATOM 2928 C CB  . LYS B 2 49  ? 111.411 132.551 62.198  1.00 195.50 ? 49  LYS B CB  1 
ATOM 2929 C CG  . LYS B 2 49  ? 112.505 133.363 61.528  1.00 195.50 ? 49  LYS B CG  1 
ATOM 2930 C CD  . LYS B 2 49  ? 113.748 132.511 61.320  1.00 195.50 ? 49  LYS B CD  1 
ATOM 2931 C CE  . LYS B 2 49  ? 113.524 131.462 60.242  1.00 195.50 ? 49  LYS B CE  1 
ATOM 2932 N NZ  . LYS B 2 49  ? 114.768 130.705 59.933  1.00 195.50 ? 49  LYS B NZ  1 
ATOM 2933 N N   . CYS B 2 50  ? 109.099 131.799 64.154  1.00 201.18 ? 50  CYS B N   1 
ATOM 2934 C CA  . CYS B 2 50  ? 108.045 130.877 64.559  1.00 201.18 ? 50  CYS B CA  1 
ATOM 2935 C C   . CYS B 2 50  ? 106.753 131.628 64.849  1.00 201.18 ? 50  CYS B C   1 
ATOM 2936 O O   . CYS B 2 50  ? 105.677 131.176 64.441  1.00 201.18 ? 50  CYS B O   1 
ATOM 2937 C CB  . CYS B 2 50  ? 108.473 130.022 65.758  1.00 201.18 ? 50  CYS B CB  1 
ATOM 2938 S SG  . CYS B 2 50  ? 108.629 130.830 67.358  1.00 201.18 ? 50  CYS B SG  1 
ATOM 2939 N N   . GLN B 2 51  ? 106.853 132.826 65.459  1.00 202.34 ? 51  GLN B N   1 
ATOM 2940 C CA  . GLN B 2 51  ? 105.666 133.660 65.686  1.00 202.34 ? 51  GLN B CA  1 
ATOM 2941 C C   . GLN B 2 51  ? 105.055 134.163 64.380  1.00 202.34 ? 51  GLN B C   1 
ATOM 2942 O O   . GLN B 2 51  ? 103.861 134.485 64.333  1.00 202.34 ? 51  GLN B O   1 
ATOM 2943 C CB  . GLN B 2 51  ? 105.997 134.848 66.591  1.00 202.34 ? 51  GLN B CB  1 
ATOM 2944 C CG  . GLN B 2 51  ? 106.299 134.503 68.037  1.00 202.34 ? 51  GLN B CG  1 
ATOM 2945 C CD  . GLN B 2 51  ? 106.875 135.682 68.798  1.00 202.34 ? 51  GLN B CD  1 
ATOM 2946 O OE1 . GLN B 2 51  ? 107.587 136.512 68.233  1.00 202.34 ? 51  GLN B OE1 1 
ATOM 2947 N NE2 . GLN B 2 51  ? 106.571 135.760 70.088  1.00 202.34 ? 51  GLN B NE2 1 
ATOM 2948 N N   . GLN B 2 52  ? 105.857 134.255 63.317  1.00 205.25 ? 52  GLN B N   1 
ATOM 2949 C CA  . GLN B 2 52  ? 105.293 134.456 61.989  1.00 205.25 ? 52  GLN B CA  1 
ATOM 2950 C C   . GLN B 2 52  ? 104.526 133.222 61.525  1.00 205.25 ? 52  GLN B C   1 
ATOM 2951 O O   . GLN B 2 52  ? 103.439 133.349 60.949  1.00 205.25 ? 52  GLN B O   1 
ATOM 2952 C CB  . GLN B 2 52  ? 106.413 134.829 61.006  1.00 205.25 ? 52  GLN B CB  1 
ATOM 2953 C CG  . GLN B 2 52  ? 105.991 135.267 59.591  1.00 205.25 ? 52  GLN B CG  1 
ATOM 2954 C CD  . GLN B 2 52  ? 105.794 134.111 58.616  1.00 205.25 ? 52  GLN B CD  1 
ATOM 2955 O OE1 . GLN B 2 52  ? 106.435 133.067 58.737  1.00 205.25 ? 52  GLN B OE1 1 
ATOM 2956 N NE2 . GLN B 2 52  ? 104.899 134.295 57.652  1.00 205.25 ? 52  GLN B NE2 1 
ATOM 2957 N N   . VAL B 2 53  ? 105.063 132.019 61.761  1.00 201.55 ? 53  VAL B N   1 
ATOM 2958 C CA  . VAL B 2 53  ? 104.489 130.862 61.071  1.00 201.55 ? 53  VAL B CA  1 
ATOM 2959 C C   . VAL B 2 53  ? 103.486 130.094 61.954  1.00 201.55 ? 53  VAL B C   1 
ATOM 2960 O O   . VAL B 2 53  ? 102.512 129.529 61.440  1.00 201.55 ? 53  VAL B O   1 
ATOM 2961 C CB  . VAL B 2 53  ? 105.622 129.979 60.495  1.00 201.55 ? 53  VAL B CB  1 
ATOM 2962 C CG1 . VAL B 2 53  ? 106.465 129.346 61.566  1.00 201.55 ? 53  VAL B CG1 1 
ATOM 2963 C CG2 . VAL B 2 53  ? 105.090 128.928 59.511  1.00 201.55 ? 53  VAL B CG2 1 
ATOM 2964 N N   . LEU B 2 54  ? 103.652 130.095 63.281  1.00 196.30 ? 54  LEU B N   1 
ATOM 2965 C CA  . LEU B 2 54  ? 102.728 129.332 64.126  1.00 196.30 ? 54  LEU B CA  1 
ATOM 2966 C C   . LEU B 2 54  ? 102.077 130.199 65.202  1.00 196.30 ? 54  LEU B C   1 
ATOM 2967 O O   . LEU B 2 54  ? 102.447 131.354 65.423  1.00 196.30 ? 54  LEU B O   1 
ATOM 2968 C CB  . LEU B 2 54  ? 103.393 128.115 64.788  1.00 196.30 ? 54  LEU B CB  1 
ATOM 2969 C CG  . LEU B 2 54  ? 103.466 126.736 64.111  1.00 196.30 ? 54  LEU B CG  1 
ATOM 2970 C CD1 . LEU B 2 54  ? 102.052 126.197 63.923  1.00 196.30 ? 54  LEU B CD1 1 
ATOM 2971 C CD2 . LEU B 2 54  ? 104.209 126.697 62.799  1.00 196.30 ? 54  LEU B CD2 1 
ATOM 2972 N N   . GLU B 2 55  ? 101.078 129.597 65.856  1.00 200.47 ? 55  GLU B N   1 
ATOM 2973 C CA  . GLU B 2 55  ? 100.319 130.226 66.932  1.00 200.47 ? 55  GLU B CA  1 
ATOM 2974 C C   . GLU B 2 55  ? 101.167 130.283 68.205  1.00 200.47 ? 55  GLU B C   1 
ATOM 2975 O O   . GLU B 2 55  ? 102.019 129.410 68.398  1.00 200.47 ? 55  GLU B O   1 
ATOM 2976 C CB  . GLU B 2 55  ? 99.036  129.418 67.173  1.00 200.47 ? 55  GLU B CB  1 
ATOM 2977 C CG  . GLU B 2 55  ? 98.075  129.404 65.996  1.00 200.47 ? 55  GLU B CG  1 
ATOM 2978 C CD  . GLU B 2 55  ? 97.463  130.762 65.718  1.00 200.47 ? 55  GLU B CD  1 
ATOM 2979 O OE1 . GLU B 2 55  ? 97.199  131.510 66.682  1.00 200.47 ? 55  GLU B OE1 1 
ATOM 2980 O OE2 . GLU B 2 55  ? 97.246  131.081 64.531  1.00 200.47 ? 55  GLU B OE2 1 
ATOM 2981 N N   . PRO B 2 56  ? 100.947 131.268 69.097  1.00 200.21 ? 56  PRO B N   1 
ATOM 2982 C CA  . PRO B 2 56  ? 101.908 131.524 70.225  1.00 200.21 ? 56  PRO B CA  1 
ATOM 2983 C C   . PRO B 2 56  ? 102.059 130.396 71.251  1.00 200.21 ? 56  PRO B C   1 
ATOM 2984 O O   . PRO B 2 56  ? 103.223 130.059 71.563  1.00 200.21 ? 56  PRO B O   1 
ATOM 2985 C CB  . PRO B 2 56  ? 101.393 132.838 70.849  1.00 200.21 ? 56  PRO B CB  1 
ATOM 2986 C CG  . PRO B 2 56  ? 100.682 133.506 69.732  1.00 200.21 ? 56  PRO B CG  1 
ATOM 2987 C CD  . PRO B 2 56  ? 100.014 132.406 68.953  1.00 200.21 ? 56  PRO B CD  1 
ATOM 2988 N N   . PRO B 2 57  ? 100.979 129.740 71.777  1.00 197.02 ? 57  PRO B N   1 
ATOM 2989 C CA  . PRO B 2 57  ? 101.248 128.676 72.773  1.00 197.02 ? 57  PRO B CA  1 
ATOM 2990 C C   . PRO B 2 57  ? 101.886 127.423 72.193  1.00 197.02 ? 57  PRO B C   1 
ATOM 2991 O O   . PRO B 2 57  ? 102.445 126.613 72.941  1.00 197.02 ? 57  PRO B O   1 
ATOM 2992 C CB  . PRO B 2 57  ? 99.856  128.364 73.342  1.00 197.02 ? 57  PRO B CB  1 
ATOM 2993 C CG  . PRO B 2 57  ? 98.958  128.686 72.261  1.00 197.02 ? 57  PRO B CG  1 
ATOM 2994 C CD  . PRO B 2 57  ? 99.508  129.943 71.715  1.00 197.02 ? 57  PRO B CD  1 
ATOM 2995 N N   . TYR B 2 58  ? 101.824 127.247 70.876  1.00 199.29 ? 58  TYR B N   1 
ATOM 2996 C CA  . TYR B 2 58  ? 102.422 126.083 70.245  1.00 199.29 ? 58  TYR B CA  1 
ATOM 2997 C C   . TYR B 2 58  ? 103.834 126.331 69.720  1.00 199.29 ? 58  TYR B C   1 
ATOM 2998 O O   . TYR B 2 58  ? 104.475 125.372 69.278  1.00 199.29 ? 58  TYR B O   1 
ATOM 2999 C CB  . TYR B 2 58  ? 101.530 125.599 69.099  1.00 199.29 ? 58  TYR B CB  1 
ATOM 3000 C CG  . TYR B 2 58  ? 100.263 124.910 69.558  1.00 199.29 ? 58  TYR B CG  1 
ATOM 3001 C CD1 . TYR B 2 58  ? 99.057  125.605 69.627  1.00 199.29 ? 58  TYR B CD1 1 
ATOM 3002 C CD2 . TYR B 2 58  ? 100.274 123.573 69.940  1.00 199.29 ? 58  TYR B CD2 1 
ATOM 3003 C CE1 . TYR B 2 58  ? 97.892  124.980 70.048  1.00 199.29 ? 58  TYR B CE1 1 
ATOM 3004 C CE2 . TYR B 2 58  ? 99.113  122.937 70.363  1.00 199.29 ? 58  TYR B CE2 1 
ATOM 3005 C CZ  . TYR B 2 58  ? 97.928  123.647 70.416  1.00 199.29 ? 58  TYR B CZ  1 
ATOM 3006 O OH  . TYR B 2 58  ? 96.776  123.021 70.837  1.00 199.29 ? 58  TYR B OH  1 
ATOM 3007 N N   . ASP B 2 59  ? 104.345 127.568 69.744  1.00 198.96 ? 59  ASP B N   1 
ATOM 3008 C CA  . ASP B 2 59  ? 105.652 127.771 69.124  1.00 198.96 ? 59  ASP B CA  1 
ATOM 3009 C C   . ASP B 2 59  ? 106.665 128.407 70.070  1.00 198.96 ? 59  ASP B C   1 
ATOM 3010 O O   . ASP B 2 59  ? 107.857 128.440 69.738  1.00 198.96 ? 59  ASP B O   1 
ATOM 3011 C CB  . ASP B 2 59  ? 105.527 128.605 67.836  1.00 198.96 ? 59  ASP B CB  1 
ATOM 3012 C CG  . ASP B 2 59  ? 105.022 130.034 68.061  1.00 198.96 ? 59  ASP B CG  1 
ATOM 3013 O OD1 . ASP B 2 59  ? 104.725 130.463 69.169  1.00 198.96 ? 59  ASP B OD1 1 
ATOM 3014 O OD2 . ASP B 2 59  ? 104.800 130.734 67.077  1.00 198.96 ? 59  ASP B OD2 1 
ATOM 3015 N N   . GLU B 2 60  ? 106.195 128.994 71.194  1.00 192.44 ? 60  GLU B N   1 
ATOM 3016 C CA  . GLU B 2 60  ? 107.145 129.536 72.177  1.00 192.44 ? 60  GLU B CA  1 
ATOM 3017 C C   . GLU B 2 60  ? 108.071 128.472 72.766  1.00 192.44 ? 60  GLU B C   1 
ATOM 3018 O O   . GLU B 2 60  ? 109.219 128.779 73.123  1.00 192.44 ? 60  GLU B O   1 
ATOM 3019 C CB  . GLU B 2 60  ? 106.423 130.273 73.310  1.00 192.44 ? 60  GLU B CB  1 
ATOM 3020 C CG  . GLU B 2 60  ? 105.765 131.581 72.901  1.00 192.44 ? 60  GLU B CG  1 
ATOM 3021 C CD  . GLU B 2 60  ? 105.068 132.272 74.057  1.00 192.44 ? 60  GLU B CD  1 
ATOM 3022 O OE1 . GLU B 2 60  ? 104.983 131.669 75.147  1.00 192.44 ? 60  GLU B OE1 1 
ATOM 3023 O OE2 . GLU B 2 60  ? 104.607 133.418 73.876  1.00 192.44 ? 60  GLU B OE2 1 
ATOM 3024 N N   . MET B 2 61  ? 107.559 127.236 72.858  1.00 186.36 ? 61  MET B N   1 
ATOM 3025 C CA  . MET B 2 61  ? 108.330 126.008 73.038  1.00 186.36 ? 61  MET B CA  1 
ATOM 3026 C C   . MET B 2 61  ? 109.583 125.937 72.166  1.00 186.36 ? 61  MET B C   1 
ATOM 3027 O O   . MET B 2 61  ? 110.698 125.767 72.672  1.00 186.36 ? 61  MET B O   1 
ATOM 3028 C CB  . MET B 2 61  ? 107.415 124.817 72.729  1.00 186.36 ? 61  MET B CB  1 
ATOM 3029 C CG  . MET B 2 61  ? 106.259 124.632 73.694  1.00 186.36 ? 61  MET B CG  1 
ATOM 3030 S SD  . MET B 2 61  ? 106.821 124.322 75.370  1.00 186.36 ? 61  MET B SD  1 
ATOM 3031 C CE  . MET B 2 61  ? 107.505 122.685 75.125  1.00 186.36 ? 61  MET B CE  1 
ATOM 3032 N N   . PHE B 2 62  ? 109.411 126.120 70.853  1.00 193.52 ? 62  PHE B N   1 
ATOM 3033 C CA  . PHE B 2 62  ? 110.508 125.908 69.912  1.00 193.52 ? 62  PHE B CA  1 
ATOM 3034 C C   . PHE B 2 62  ? 111.542 127.027 69.989  1.00 193.52 ? 62  PHE B C   1 
ATOM 3035 O O   . PHE B 2 62  ? 112.749 126.768 69.933  1.00 193.52 ? 62  PHE B O   1 
ATOM 3036 C CB  . PHE B 2 62  ? 109.956 125.770 68.492  1.00 193.52 ? 62  PHE B CB  1 
ATOM 3037 C CG  . PHE B 2 62  ? 111.010 125.506 67.456  1.00 193.52 ? 62  PHE B CG  1 
ATOM 3038 C CD1 . PHE B 2 62  ? 111.584 124.246 67.343  1.00 193.52 ? 62  PHE B CD1 1 
ATOM 3039 C CD2 . PHE B 2 62  ? 111.420 126.510 66.587  1.00 193.52 ? 62  PHE B CD2 1 
ATOM 3040 C CE1 . PHE B 2 62  ? 112.559 123.994 66.392  1.00 193.52 ? 62  PHE B CE1 1 
ATOM 3041 C CE2 . PHE B 2 62  ? 112.393 126.265 65.632  1.00 193.52 ? 62  PHE B CE2 1 
ATOM 3042 C CZ  . PHE B 2 62  ? 112.963 125.008 65.536  1.00 193.52 ? 62  PHE B CZ  1 
ATOM 3043 N N   . ALA B 2 63  ? 111.085 128.278 70.126  1.00 188.14 ? 63  ALA B N   1 
ATOM 3044 C CA  . ALA B 2 63  ? 112.001 129.417 70.207  1.00 188.14 ? 63  ALA B CA  1 
ATOM 3045 C C   . ALA B 2 63  ? 112.804 129.403 71.503  1.00 188.14 ? 63  ALA B C   1 
ATOM 3046 O O   . ALA B 2 63  ? 114.022 129.668 71.497  1.00 188.14 ? 63  ALA B O   1 
ATOM 3047 C CB  . ALA B 2 63  ? 111.218 130.723 70.080  1.00 188.14 ? 63  ALA B CB  1 
ATOM 3048 N N   . ALA B 2 64  ? 112.141 129.061 72.620  1.00 185.62 ? 64  ALA B N   1 
ATOM 3049 C CA  . ALA B 2 64  ? 112.844 128.872 73.883  1.00 185.62 ? 64  ALA B CA  1 
ATOM 3050 C C   . ALA B 2 64  ? 113.825 127.712 73.797  1.00 185.62 ? 64  ALA B C   1 
ATOM 3051 O O   . ALA B 2 64  ? 114.949 127.819 74.297  1.00 185.62 ? 64  ALA B O   1 
ATOM 3052 C CB  . ALA B 2 64  ? 111.840 128.645 75.012  1.00 185.62 ? 64  ALA B CB  1 
ATOM 3053 N N   . HIS B 2 65  ? 113.435 126.632 73.104  1.00 179.55 ? 65  HIS B N   1 
ATOM 3054 C CA  . HIS B 2 65  ? 114.292 125.460 72.944  1.00 179.55 ? 65  HIS B CA  1 
ATOM 3055 C C   . HIS B 2 65  ? 115.547 125.778 72.139  1.00 179.55 ? 65  HIS B C   1 
ATOM 3056 O O   . HIS B 2 65  ? 116.634 125.297 72.476  1.00 179.55 ? 65  HIS B O   1 
ATOM 3057 C CB  . HIS B 2 65  ? 113.504 124.333 72.281  1.00 179.55 ? 65  HIS B CB  1 
ATOM 3058 C CG  . HIS B 2 65  ? 113.922 122.965 72.719  1.00 179.55 ? 65  HIS B CG  1 
ATOM 3059 N ND1 . HIS B 2 65  ? 113.290 121.820 72.283  1.00 179.55 ? 65  HIS B ND1 1 
ATOM 3060 C CD2 . HIS B 2 65  ? 114.906 122.557 73.554  1.00 179.55 ? 65  HIS B CD2 1 
ATOM 3061 C CE1 . HIS B 2 65  ? 113.868 120.766 72.830  1.00 179.55 ? 65  HIS B CE1 1 
ATOM 3062 N NE2 . HIS B 2 65  ? 114.851 121.186 73.607  1.00 179.55 ? 65  HIS B NE2 1 
ATOM 3063 N N   . LEU B 2 66  ? 115.417 126.609 71.095  1.00 183.33 ? 66  LEU B N   1 
ATOM 3064 C CA  . LEU B 2 66  ? 116.590 127.079 70.354  1.00 183.33 ? 66  LEU B CA  1 
ATOM 3065 C C   . LEU B 2 66  ? 117.507 127.925 71.231  1.00 183.33 ? 66  LEU B C   1 
ATOM 3066 O O   . LEU B 2 66  ? 118.732 127.725 71.230  1.00 183.33 ? 66  LEU B O   1 
ATOM 3067 C CB  . LEU B 2 66  ? 116.184 127.882 69.116  1.00 183.33 ? 66  LEU B CB  1 
ATOM 3068 C CG  . LEU B 2 66  ? 115.352 127.290 67.983  1.00 183.33 ? 66  LEU B CG  1 
ATOM 3069 C CD1 . LEU B 2 66  ? 115.006 128.390 66.994  1.00 183.33 ? 66  LEU B CD1 1 
ATOM 3070 C CD2 . LEU B 2 66  ? 116.094 126.157 67.296  1.00 183.33 ? 66  LEU B CD2 1 
ATOM 3071 N N   . ARG B 2 67  ? 116.929 128.847 72.019  1.00 181.37 ? 67  ARG B N   1 
ATOM 3072 C CA  . ARG B 2 67  ? 117.777 129.733 72.819  1.00 181.37 ? 67  ARG B CA  1 
ATOM 3073 C C   . ARG B 2 67  ? 118.457 128.996 73.978  1.00 181.37 ? 67  ARG B C   1 
ATOM 3074 O O   . ARG B 2 67  ? 119.601 129.317 74.328  1.00 181.37 ? 67  ARG B O   1 
ATOM 3075 C CB  . ARG B 2 67  ? 116.979 130.956 73.302  1.00 181.37 ? 67  ARG B CB  1 
ATOM 3076 C CG  . ARG B 2 67  ? 116.273 130.861 74.651  1.00 181.37 ? 67  ARG B CG  1 
ATOM 3077 C CD  . ARG B 2 67  ? 115.829 132.236 75.125  1.00 181.37 ? 67  ARG B CD  1 
ATOM 3078 N NE  . ARG B 2 67  ? 115.091 132.963 74.099  1.00 181.37 ? 67  ARG B NE  1 
ATOM 3079 C CZ  . ARG B 2 67  ? 113.773 132.921 73.951  1.00 181.37 ? 67  ARG B CZ  1 
ATOM 3080 N NH1 . ARG B 2 67  ? 113.008 132.212 74.765  1.00 181.37 ? 67  ARG B NH1 1 
ATOM 3081 N NH2 . ARG B 2 67  ? 113.208 133.614 72.966  1.00 181.37 ? 67  ARG B NH2 1 
ATOM 3082 N N   . CYS B 2 68  ? 117.845 127.936 74.514  1.00 182.59 ? 68  CYS B N   1 
ATOM 3083 C CA  . CYS B 2 68  ? 118.522 127.265 75.620  1.00 182.59 ? 68  CYS B CA  1 
ATOM 3084 C C   . CYS B 2 68  ? 119.337 126.064 75.156  1.00 182.59 ? 68  CYS B C   1 
ATOM 3085 O O   . CYS B 2 68  ? 120.223 125.617 75.885  1.00 182.59 ? 68  CYS B O   1 
ATOM 3086 C CB  . CYS B 2 68  ? 117.549 126.891 76.736  1.00 182.59 ? 68  CYS B CB  1 
ATOM 3087 S SG  . CYS B 2 68  ? 116.236 125.741 76.408  1.00 182.59 ? 68  CYS B SG  1 
ATOM 3088 N N   . THR B 2 69  ? 119.136 125.578 73.928  1.00 183.56 ? 69  THR B N   1 
ATOM 3089 C CA  . THR B 2 69  ? 120.156 124.706 73.351  1.00 183.56 ? 69  THR B CA  1 
ATOM 3090 C C   . THR B 2 69  ? 121.392 125.513 72.975  1.00 183.56 ? 69  THR B C   1 
ATOM 3091 O O   . THR B 2 69  ? 122.518 125.003 73.020  1.00 183.56 ? 69  THR B O   1 
ATOM 3092 C CB  . THR B 2 69  ? 119.614 123.939 72.144  1.00 183.56 ? 69  THR B CB  1 
ATOM 3093 O OG1 . THR B 2 69  ? 118.871 124.818 71.292  1.00 183.56 ? 69  THR B OG1 1 
ATOM 3094 C CG2 . THR B 2 69  ? 118.750 122.759 72.587  1.00 183.56 ? 69  THR B CG2 1 
ATOM 3095 N N   . TYR B 2 70  ? 121.199 126.791 72.622  1.00 185.66 ? 70  TYR B N   1 
ATOM 3096 C CA  . TYR B 2 70  ? 122.332 127.706 72.504  1.00 185.66 ? 70  TYR B CA  1 
ATOM 3097 C C   . TYR B 2 70  ? 122.996 127.946 73.859  1.00 185.66 ? 70  TYR B C   1 
ATOM 3098 O O   . TYR B 2 70  ? 124.225 128.064 73.940  1.00 185.66 ? 70  TYR B O   1 
ATOM 3099 C CB  . TYR B 2 70  ? 121.869 129.023 71.871  1.00 185.66 ? 70  TYR B CB  1 
ATOM 3100 C CG  . TYR B 2 70  ? 122.668 130.253 72.261  1.00 185.66 ? 70  TYR B CG  1 
ATOM 3101 C CD1 . TYR B 2 70  ? 123.947 130.471 71.746  1.00 185.66 ? 70  TYR B CD1 1 
ATOM 3102 C CD2 . TYR B 2 70  ? 122.135 131.206 73.128  1.00 185.66 ? 70  TYR B CD2 1 
ATOM 3103 C CE1 . TYR B 2 70  ? 124.678 131.596 72.099  1.00 185.66 ? 70  TYR B CE1 1 
ATOM 3104 C CE2 . TYR B 2 70  ? 122.859 132.334 73.485  1.00 185.66 ? 70  TYR B CE2 1 
ATOM 3105 C CZ  . TYR B 2 70  ? 124.128 132.522 72.967  1.00 185.66 ? 70  TYR B CZ  1 
ATOM 3106 O OH  . TYR B 2 70  ? 124.849 133.641 73.317  1.00 185.66 ? 70  TYR B OH  1 
ATOM 3107 N N   . ALA B 2 71  ? 122.198 128.030 74.932  1.00 181.25 ? 71  ALA B N   1 
ATOM 3108 C CA  . ALA B 2 71  ? 122.759 128.244 76.269  1.00 181.25 ? 71  ALA B CA  1 
ATOM 3109 C C   . ALA B 2 71  ? 123.521 127.020 76.782  1.00 181.25 ? 71  ALA B C   1 
ATOM 3110 O O   . ALA B 2 71  ? 124.541 127.162 77.467  1.00 181.25 ? 71  ALA B O   1 
ATOM 3111 C CB  . ALA B 2 71  ? 121.650 128.629 77.247  1.00 181.25 ? 71  ALA B CB  1 
ATOM 3112 N N   . VAL B 2 72  ? 123.026 125.812 76.496  1.00 181.49 ? 72  VAL B N   1 
ATOM 3113 C CA  . VAL B 2 72  ? 123.772 124.588 76.802  1.00 181.49 ? 72  VAL B CA  1 
ATOM 3114 C C   . VAL B 2 72  ? 124.994 124.430 75.905  1.00 181.49 ? 72  VAL B C   1 
ATOM 3115 O O   . VAL B 2 72  ? 126.026 123.918 76.369  1.00 181.49 ? 72  VAL B O   1 
ATOM 3116 C CB  . VAL B 2 72  ? 122.788 123.395 76.753  1.00 181.49 ? 72  VAL B CB  1 
ATOM 3117 C CG1 . VAL B 2 72  ? 123.471 122.042 76.945  1.00 181.49 ? 72  VAL B CG1 1 
ATOM 3118 C CG2 . VAL B 2 72  ? 121.764 123.531 77.865  1.00 181.49 ? 72  VAL B CG2 1 
ATOM 3119 N N   . GLY B 2 73  ? 124.937 124.938 74.665  1.00 186.04 ? 73  GLY B N   1 
ATOM 3120 C CA  . GLY B 2 73  ? 126.022 124.722 73.713  1.00 186.04 ? 73  GLY B CA  1 
ATOM 3121 C C   . GLY B 2 73  ? 127.315 125.439 74.067  1.00 186.04 ? 73  GLY B C   1 
ATOM 3122 O O   . GLY B 2 73  ? 128.396 125.034 73.632  1.00 186.04 ? 73  GLY B O   1 
ATOM 3123 N N   . ASN B 2 74  ? 127.228 126.507 74.862  1.00 188.05 ? 74  ASN B N   1 
ATOM 3124 C CA  . ASN B 2 74  ? 128.408 127.111 75.468  1.00 188.05 ? 74  ASN B CA  1 
ATOM 3125 C C   . ASN B 2 74  ? 128.439 126.934 76.986  1.00 188.05 ? 74  ASN B C   1 
ATOM 3126 O O   . ASN B 2 74  ? 129.159 127.673 77.669  1.00 188.05 ? 74  ASN B O   1 
ATOM 3127 C CB  . ASN B 2 74  ? 128.522 128.591 75.082  1.00 188.05 ? 74  ASN B CB  1 
ATOM 3128 C CG  . ASN B 2 74  ? 127.250 129.383 75.341  1.00 188.05 ? 74  ASN B CG  1 
ATOM 3129 O OD1 . ASN B 2 74  ? 126.273 128.871 75.883  1.00 188.05 ? 74  ASN B OD1 1 
ATOM 3130 N ND2 . ASN B 2 74  ? 127.264 130.651 74.949  1.00 188.05 ? 74  ASN B ND2 1 
ATOM 3131 N N   . HIS B 2 75  ? 127.658 125.970 77.505  1.00 182.11 ? 75  HIS B N   1 
ATOM 3132 C CA  . HIS B 2 75  ? 127.625 125.548 78.916  1.00 182.11 ? 75  HIS B CA  1 
ATOM 3133 C C   . HIS B 2 75  ? 127.240 126.694 79.858  1.00 182.11 ? 75  HIS B C   1 
ATOM 3134 O O   . HIS B 2 75  ? 128.037 127.157 80.676  1.00 182.11 ? 75  HIS B O   1 
ATOM 3135 C CB  . HIS B 2 75  ? 128.952 124.894 79.336  1.00 182.11 ? 75  HIS B CB  1 
ATOM 3136 C CG  . HIS B 2 75  ? 128.886 124.151 80.637  1.00 182.11 ? 75  HIS B CG  1 
ATOM 3137 N ND1 . HIS B 2 75  ? 128.870 124.785 81.862  1.00 182.11 ? 75  HIS B ND1 1 
ATOM 3138 C CD2 . HIS B 2 75  ? 128.829 122.824 80.902  1.00 182.11 ? 75  HIS B CD2 1 
ATOM 3139 C CE1 . HIS B 2 75  ? 128.809 123.881 82.823  1.00 182.11 ? 75  HIS B CE1 1 
ATOM 3140 N NE2 . HIS B 2 75  ? 128.783 122.683 82.268  1.00 182.11 ? 75  HIS B NE2 1 
ATOM 3141 N N   . ASP B 2 76  ? 126.003 127.166 79.719  1.00 174.56 ? 76  ASP B N   1 
ATOM 3142 C CA  . ASP B 2 76  ? 125.400 128.097 80.668  1.00 174.56 ? 76  ASP B CA  1 
ATOM 3143 C C   . ASP B 2 76  ? 124.156 127.389 81.196  1.00 174.56 ? 76  ASP B C   1 
ATOM 3144 O O   . ASP B 2 76  ? 123.301 126.960 80.413  1.00 174.56 ? 76  ASP B O   1 
ATOM 3145 C CB  . ASP B 2 76  ? 125.081 129.437 79.996  1.00 174.56 ? 76  ASP B CB  1 
ATOM 3146 C CG  . ASP B 2 76  ? 124.624 130.527 80.981  1.00 174.56 ? 76  ASP B CG  1 
ATOM 3147 O OD1 . ASP B 2 76  ? 125.234 131.617 80.946  1.00 174.56 ? 76  ASP B OD1 1 
ATOM 3148 O OD2 . ASP B 2 76  ? 123.662 130.345 81.758  1.00 174.56 ? 76  ASP B OD2 1 
ATOM 3149 N N   . PHE B 2 77  ? 124.054 127.267 82.522  1.00 165.88 ? 77  PHE B N   1 
ATOM 3150 C CA  . PHE B 2 77  ? 123.000 126.440 83.103  1.00 165.88 ? 77  PHE B CA  1 
ATOM 3151 C C   . PHE B 2 77  ? 121.843 127.272 83.643  1.00 165.88 ? 77  PHE B C   1 
ATOM 3152 O O   . PHE B 2 77  ? 120.716 126.772 83.730  1.00 165.88 ? 77  PHE B O   1 
ATOM 3153 C CB  . PHE B 2 77  ? 123.574 125.554 84.212  1.00 165.88 ? 77  PHE B CB  1 
ATOM 3154 C CG  . PHE B 2 77  ? 124.130 124.235 83.729  1.00 165.88 ? 77  PHE B CG  1 
ATOM 3155 C CD1 . PHE B 2 77  ? 124.338 123.196 84.628  1.00 165.88 ? 77  PHE B CD1 1 
ATOM 3156 C CD2 . PHE B 2 77  ? 124.442 124.028 82.389  1.00 165.88 ? 77  PHE B CD2 1 
ATOM 3157 C CE1 . PHE B 2 77  ? 124.847 121.978 84.203  1.00 165.88 ? 77  PHE B CE1 1 
ATOM 3158 C CE2 . PHE B 2 77  ? 124.952 122.814 81.956  1.00 165.88 ? 77  PHE B CE2 1 
ATOM 3159 C CZ  . PHE B 2 77  ? 125.153 121.788 82.865  1.00 165.88 ? 77  PHE B CZ  1 
ATOM 3160 N N   . ILE B 2 78  ? 122.102 128.528 84.018  1.00 167.42 ? 78  ILE B N   1 
ATOM 3161 C CA  . ILE B 2 78  ? 121.065 129.379 84.605  1.00 167.42 ? 78  ILE B CA  1 
ATOM 3162 C C   . ILE B 2 78  ? 120.057 129.794 83.533  1.00 167.42 ? 78  ILE B C   1 
ATOM 3163 O O   . ILE B 2 78  ? 118.836 129.802 83.759  1.00 167.42 ? 78  ILE B O   1 
ATOM 3164 C CB  . ILE B 2 78  ? 121.713 130.595 85.294  1.00 167.42 ? 78  ILE B CB  1 
ATOM 3165 C CG1 . ILE B 2 78  ? 122.608 130.130 86.442  1.00 167.42 ? 78  ILE B CG1 1 
ATOM 3166 C CG2 . ILE B 2 78  ? 120.670 131.522 85.885  1.00 167.42 ? 78  ILE B CG2 1 
ATOM 3167 C CD1 . ILE B 2 78  ? 123.487 131.224 87.014  1.00 167.42 ? 78  ILE B CD1 1 
ATOM 3168 N N   . GLU B 2 79  ? 120.565 130.112 82.335  1.00 171.35 ? 79  GLU B N   1 
ATOM 3169 C CA  . GLU B 2 79  ? 119.706 130.431 81.198  1.00 171.35 ? 79  GLU B CA  1 
ATOM 3170 C C   . GLU B 2 79  ? 118.896 129.221 80.747  1.00 171.35 ? 79  GLU B C   1 
ATOM 3171 O O   . GLU B 2 79  ? 117.733 129.367 80.359  1.00 171.35 ? 79  GLU B O   1 
ATOM 3172 C CB  . GLU B 2 79  ? 120.545 130.966 80.035  1.00 171.35 ? 79  GLU B CB  1 
ATOM 3173 C CG  . GLU B 2 79  ? 121.319 132.247 80.332  1.00 171.35 ? 79  GLU B CG  1 
ATOM 3174 C CD  . GLU B 2 79  ? 120.424 133.447 80.579  1.00 171.35 ? 79  GLU B CD  1 
ATOM 3175 O OE1 . GLU B 2 79  ? 119.358 133.544 79.934  1.00 171.35 ? 79  GLU B OE1 1 
ATOM 3176 O OE2 . GLU B 2 79  ? 120.791 134.299 81.416  1.00 171.35 ? 79  GLU B OE2 1 
ATOM 3177 N N   . ALA B 2 80  ? 119.475 128.020 80.830  1.00 169.10 ? 80  ALA B N   1 
ATOM 3178 C CA  . ALA B 2 80  ? 118.731 126.804 80.505  1.00 169.10 ? 80  ALA B CA  1 
ATOM 3179 C C   . ALA B 2 80  ? 117.695 126.483 81.578  1.00 169.10 ? 80  ALA B C   1 
ATOM 3180 O O   . ALA B 2 80  ? 116.653 125.879 81.294  1.00 169.10 ? 80  ALA B O   1 
ATOM 3181 C CB  . ALA B 2 80  ? 119.696 125.634 80.318  1.00 169.10 ? 80  ALA B CB  1 
ATOM 3182 N N   . TYR B 2 81  ? 117.967 126.881 82.824  1.00 161.29 ? 81  TYR B N   1 
ATOM 3183 C CA  . TYR B 2 81  ? 116.992 126.703 83.896  1.00 161.29 ? 81  TYR B CA  1 
ATOM 3184 C C   . TYR B 2 81  ? 115.786 127.616 83.694  1.00 161.29 ? 81  TYR B C   1 
ATOM 3185 O O   . TYR B 2 81  ? 114.632 127.185 83.844  1.00 161.29 ? 81  TYR B O   1 
ATOM 3186 C CB  . TYR B 2 81  ? 117.662 126.961 85.247  1.00 161.29 ? 81  TYR B CB  1 
ATOM 3187 C CG  . TYR B 2 81  ? 116.758 126.760 86.440  1.00 161.29 ? 81  TYR B CG  1 
ATOM 3188 C CD1 . TYR B 2 81  ? 116.432 125.479 86.875  1.00 161.29 ? 81  TYR B CD1 1 
ATOM 3189 C CD2 . TYR B 2 81  ? 116.248 127.847 87.146  1.00 161.29 ? 81  TYR B CD2 1 
ATOM 3190 C CE1 . TYR B 2 81  ? 115.611 125.282 87.971  1.00 161.29 ? 81  TYR B CE1 1 
ATOM 3191 C CE2 . TYR B 2 81  ? 115.424 127.661 88.247  1.00 161.29 ? 81  TYR B CE2 1 
ATOM 3192 C CZ  . TYR B 2 81  ? 115.111 126.375 88.652  1.00 161.29 ? 81  TYR B CZ  1 
ATOM 3193 O OH  . TYR B 2 81  ? 114.296 126.176 89.742  1.00 161.29 ? 81  TYR B OH  1 
ATOM 3194 N N   . LYS B 2 82  ? 116.041 128.877 83.312  1.00 167.33 ? 82  LYS B N   1 
ATOM 3195 C CA  . LYS B 2 82  ? 114.942 129.788 82.987  1.00 167.33 ? 82  LYS B CA  1 
ATOM 3196 C C   . LYS B 2 82  ? 114.212 129.347 81.724  1.00 167.33 ? 82  LYS B C   1 
ATOM 3197 O O   . LYS B 2 82  ? 112.987 129.513 81.622  1.00 167.33 ? 82  LYS B O   1 
ATOM 3198 C CB  . LYS B 2 82  ? 115.438 131.223 82.812  1.00 167.33 ? 82  LYS B CB  1 
ATOM 3199 C CG  . LYS B 2 82  ? 116.034 131.870 84.041  1.00 167.33 ? 82  LYS B CG  1 
ATOM 3200 C CD  . LYS B 2 82  ? 116.403 133.317 83.734  1.00 167.33 ? 82  LYS B CD  1 
ATOM 3201 C CE  . LYS B 2 82  ? 117.585 133.429 82.794  1.00 167.33 ? 82  LYS B CE  1 
ATOM 3202 N NZ  . LYS B 2 82  ? 118.830 132.925 83.409  1.00 167.33 ? 82  LYS B NZ  1 
ATOM 3203 N N   . CYS B 2 83  ? 114.955 128.772 80.764  1.00 170.40 ? 83  CYS B N   1 
ATOM 3204 C CA  . CYS B 2 83  ? 114.365 128.129 79.592  1.00 170.40 ? 83  CYS B CA  1 
ATOM 3205 C C   . CYS B 2 83  ? 113.369 127.049 79.953  1.00 170.40 ? 83  CYS B C   1 
ATOM 3206 O O   . CYS B 2 83  ? 112.228 127.088 79.499  1.00 170.40 ? 83  CYS B O   1 
ATOM 3207 C CB  . CYS B 2 83  ? 115.440 127.506 78.715  1.00 170.40 ? 83  CYS B CB  1 
ATOM 3208 S SG  . CYS B 2 83  ? 114.697 126.742 77.266  1.00 170.40 ? 83  CYS B SG  1 
ATOM 3209 N N   . GLN B 2 84  ? 113.777 126.089 80.781  1.00 165.33 ? 84  GLN B N   1 
ATOM 3210 C CA  . GLN B 2 84  ? 112.898 124.960 81.058  1.00 165.33 ? 84  GLN B CA  1 
ATOM 3211 C C   . GLN B 2 84  ? 111.761 125.353 81.996  1.00 165.33 ? 84  GLN B C   1 
ATOM 3212 O O   . GLN B 2 84  ? 110.693 124.730 81.969  1.00 165.33 ? 84  GLN B O   1 
ATOM 3213 C CB  . GLN B 2 84  ? 113.719 123.792 81.591  1.00 165.33 ? 84  GLN B CB  1 
ATOM 3214 C CG  . GLN B 2 84  ? 114.655 123.241 80.527  1.00 165.33 ? 84  GLN B CG  1 
ATOM 3215 C CD  . GLN B 2 84  ? 115.510 122.096 81.010  1.00 165.33 ? 84  GLN B CD  1 
ATOM 3216 O OE1 . GLN B 2 84  ? 115.473 121.728 82.180  1.00 165.33 ? 84  GLN B OE1 1 
ATOM 3217 N NE2 . GLN B 2 84  ? 116.275 121.510 80.100  1.00 165.33 ? 84  GLN B NE2 1 
ATOM 3218 N N   . THR B 2 85  ? 111.942 126.433 82.769  1.00 162.05 ? 85  THR B N   1 
ATOM 3219 C CA  . THR B 2 85  ? 110.814 127.055 83.465  1.00 162.05 ? 85  THR B CA  1 
ATOM 3220 C C   . THR B 2 85  ? 109.779 127.602 82.478  1.00 162.05 ? 85  THR B C   1 
ATOM 3221 O O   . THR B 2 85  ? 108.571 127.355 82.628  1.00 162.05 ? 85  THR B O   1 
ATOM 3222 C CB  . THR B 2 85  ? 111.326 128.169 84.380  1.00 162.05 ? 85  THR B CB  1 
ATOM 3223 O OG1 . THR B 2 85  ? 112.310 127.639 85.278  1.00 162.05 ? 85  THR B OG1 1 
ATOM 3224 C CG2 . THR B 2 85  ? 110.187 128.777 85.181  1.00 162.05 ? 85  THR B CG2 1 
ATOM 3225 N N   . VAL B 2 86  ? 110.249 128.311 81.440  1.00 162.74 ? 86  VAL B N   1 
ATOM 3226 C CA  . VAL B 2 86  ? 109.362 128.832 80.392  1.00 162.74 ? 86  VAL B CA  1 
ATOM 3227 C C   . VAL B 2 86  ? 108.725 127.686 79.601  1.00 162.74 ? 86  VAL B C   1 
ATOM 3228 O O   . VAL B 2 86  ? 107.542 127.742 79.243  1.00 162.74 ? 86  VAL B O   1 
ATOM 3229 C CB  . VAL B 2 86  ? 110.141 129.816 79.490  1.00 162.74 ? 86  VAL B CB  1 
ATOM 3230 C CG1 . VAL B 2 86  ? 109.380 130.196 78.222  1.00 162.74 ? 86  VAL B CG1 1 
ATOM 3231 C CG2 . VAL B 2 86  ? 110.441 131.090 80.258  1.00 162.74 ? 86  VAL B CG2 1 
ATOM 3232 N N   . ILE B 2 87  ? 109.489 126.607 79.383  1.00 168.38 ? 87  ILE B N   1 
ATOM 3233 C CA  . ILE B 2 87  ? 109.020 125.418 78.663  1.00 168.38 ? 87  ILE B CA  1 
ATOM 3234 C C   . ILE B 2 87  ? 107.876 124.732 79.403  1.00 168.38 ? 87  ILE B C   1 
ATOM 3235 O O   . ILE B 2 87  ? 106.821 124.462 78.813  1.00 168.38 ? 87  ILE B O   1 
ATOM 3236 C CB  . ILE B 2 87  ? 110.201 124.453 78.407  1.00 168.38 ? 87  ILE B CB  1 
ATOM 3237 C CG1 . ILE B 2 87  ? 111.126 124.985 77.307  1.00 168.38 ? 87  ILE B CG1 1 
ATOM 3238 C CG2 . ILE B 2 87  ? 109.739 123.031 78.109  1.00 168.38 ? 87  ILE B CG2 1 
ATOM 3239 C CD1 . ILE B 2 87  ? 110.471 125.105 75.973  1.00 168.38 ? 87  ILE B CD1 1 
ATOM 3240 N N   . VAL B 2 88  ? 108.043 124.488 80.710  1.00 164.47 ? 88  VAL B N   1 
ATOM 3241 C CA  . VAL B 2 88  ? 106.993 123.833 81.493  1.00 164.47 ? 88  VAL B CA  1 
ATOM 3242 C C   . VAL B 2 88  ? 105.773 124.741 81.669  1.00 164.47 ? 88  VAL B C   1 
ATOM 3243 O O   . VAL B 2 88  ? 104.634 124.270 81.550  1.00 164.47 ? 88  VAL B O   1 
ATOM 3244 C CB  . VAL B 2 88  ? 107.574 123.339 82.836  1.00 164.47 ? 88  VAL B CB  1 
ATOM 3245 C CG1 . VAL B 2 88  ? 106.503 122.749 83.742  1.00 164.47 ? 88  VAL B CG1 1 
ATOM 3246 C CG2 . VAL B 2 88  ? 108.604 122.259 82.570  1.00 164.47 ? 88  VAL B CG2 1 
ATOM 3247 N N   . GLN B 2 89  ? 105.978 126.057 81.847  1.00 169.75 ? 89  GLN B N   1 
ATOM 3248 C CA  . GLN B 2 89  ? 104.841 126.971 81.998  1.00 169.75 ? 89  GLN B CA  1 
ATOM 3249 C C   . GLN B 2 89  ? 104.051 127.133 80.696  1.00 169.75 ? 89  GLN B C   1 
ATOM 3250 O O   . GLN B 2 89  ? 102.810 127.085 80.705  1.00 169.75 ? 89  GLN B O   1 
ATOM 3251 C CB  . GLN B 2 89  ? 105.331 128.330 82.497  1.00 169.75 ? 89  GLN B CB  1 
ATOM 3252 C CG  . GLN B 2 89  ? 104.243 129.206 83.100  1.00 169.75 ? 89  GLN B CG  1 
ATOM 3253 C CD  . GLN B 2 89  ? 103.652 130.180 82.098  1.00 169.75 ? 89  GLN B CD  1 
ATOM 3254 O OE1 . GLN B 2 89  ? 104.325 130.610 81.162  1.00 169.75 ? 89  GLN B OE1 1 
ATOM 3255 N NE2 . GLN B 2 89  ? 102.385 130.528 82.289  1.00 169.75 ? 89  GLN B NE2 1 
ATOM 3256 N N   . SER B 2 90  ? 104.750 127.290 79.567  1.00 168.16 ? 90  SER B N   1 
ATOM 3257 C CA  . SER B 2 90  ? 104.080 127.467 78.284  1.00 168.16 ? 90  SER B CA  1 
ATOM 3258 C C   . SER B 2 90  ? 103.422 126.176 77.820  1.00 168.16 ? 90  SER B C   1 
ATOM 3259 O O   . SER B 2 90  ? 102.342 126.208 77.215  1.00 168.16 ? 90  SER B O   1 
ATOM 3260 C CB  . SER B 2 90  ? 105.074 127.966 77.236  1.00 168.16 ? 90  SER B CB  1 
ATOM 3261 O OG  . SER B 2 90  ? 105.869 126.902 76.741  1.00 168.16 ? 90  SER B OG  1 
ATOM 3262 N N   . PHE B 2 91  ? 104.035 125.024 78.116  1.00 166.92 ? 91  PHE B N   1 
ATOM 3263 C CA  . PHE B 2 91  ? 103.412 123.765 77.736  1.00 166.92 ? 91  PHE B CA  1 
ATOM 3264 C C   . PHE B 2 91  ? 102.243 123.432 78.654  1.00 166.92 ? 91  PHE B C   1 
ATOM 3265 O O   . PHE B 2 91  ? 101.285 122.784 78.230  1.00 166.92 ? 91  PHE B O   1 
ATOM 3266 C CB  . PHE B 2 91  ? 104.444 122.640 77.718  1.00 166.92 ? 91  PHE B CB  1 
ATOM 3267 C CG  . PHE B 2 91  ? 103.880 121.323 77.288  1.00 166.92 ? 91  PHE B CG  1 
ATOM 3268 C CD1 . PHE B 2 91  ? 103.456 121.143 75.979  1.00 166.92 ? 91  PHE B CD1 1 
ATOM 3269 C CD2 . PHE B 2 91  ? 103.791 120.260 78.176  1.00 166.92 ? 91  PHE B CD2 1 
ATOM 3270 C CE1 . PHE B 2 91  ? 102.925 119.935 75.566  1.00 166.92 ? 91  PHE B CE1 1 
ATOM 3271 C CE2 . PHE B 2 91  ? 103.276 119.043 77.762  1.00 166.92 ? 91  PHE B CE2 1 
ATOM 3272 C CZ  . PHE B 2 91  ? 102.839 118.879 76.460  1.00 166.92 ? 91  PHE B CZ  1 
ATOM 3273 N N   . LEU B 2 92  ? 102.284 123.905 79.907  1.00 164.43 ? 92  LEU B N   1 
ATOM 3274 C CA  . LEU B 2 92  ? 101.121 123.799 80.787  1.00 164.43 ? 92  LEU B CA  1 
ATOM 3275 C C   . LEU B 2 92  ? 99.953  124.632 80.275  1.00 164.43 ? 92  LEU B C   1 
ATOM 3276 O O   . LEU B 2 92  ? 98.803  124.173 80.286  1.00 164.43 ? 92  LEU B O   1 
ATOM 3277 C CB  . LEU B 2 92  ? 101.490 124.241 82.200  1.00 164.43 ? 92  LEU B CB  1 
ATOM 3278 C CG  . LEU B 2 92  ? 100.558 123.753 83.308  1.00 164.43 ? 92  LEU B CG  1 
ATOM 3279 C CD1 . LEU B 2 92  ? 100.498 122.232 83.352  1.00 164.43 ? 92  LEU B CD1 1 
ATOM 3280 C CD2 . LEU B 2 92  ? 100.976 124.338 84.645  1.00 164.43 ? 92  LEU B CD2 1 
ATOM 3281 N N   . ARG B 2 93  ? 100.236 125.855 79.808  1.00 163.98 ? 93  ARG B N   1 
ATOM 3282 C CA  . ARG B 2 93  ? 99.177  126.707 79.268  1.00 163.98 ? 93  ARG B CA  1 
ATOM 3283 C C   . ARG B 2 93  ? 98.625  126.159 77.954  1.00 163.98 ? 93  ARG B C   1 
ATOM 3284 O O   . ARG B 2 93  ? 97.406  126.164 77.735  1.00 163.98 ? 93  ARG B O   1 
ATOM 3285 C CB  . ARG B 2 93  ? 99.696  128.137 79.084  1.00 163.98 ? 93  ARG B CB  1 
ATOM 3286 C CG  . ARG B 2 93  ? 98.638  129.267 79.083  1.00 163.98 ? 93  ARG B CG  1 
ATOM 3287 C CD  . ARG B 2 93  ? 97.624  129.333 80.260  1.00 163.98 ? 93  ARG B CD  1 
ATOM 3288 N NE  . ARG B 2 93  ? 98.105  128.856 81.554  1.00 163.98 ? 93  ARG B NE  1 
ATOM 3289 C CZ  . ARG B 2 93  ? 98.853  129.568 82.386  1.00 163.98 ? 93  ARG B CZ  1 
ATOM 3290 N NH1 . ARG B 2 93  ? 99.225  130.804 82.096  1.00 163.98 ? 93  ARG B NH1 1 
ATOM 3291 N NH2 . ARG B 2 93  ? 99.238  129.025 83.537  1.00 163.98 ? 93  ARG B NH2 1 
ATOM 3292 N N   . ALA B 2 94  ? 99.499  125.640 77.087  1.00 172.47 ? 94  ALA B N   1 
ATOM 3293 C CA  . ALA B 2 94  ? 99.042  125.060 75.828  1.00 172.47 ? 94  ALA B CA  1 
ATOM 3294 C C   . ALA B 2 94  ? 98.383  123.700 76.033  1.00 172.47 ? 94  ALA B C   1 
ATOM 3295 O O   . ALA B 2 94  ? 97.593  123.260 75.190  1.00 172.47 ? 94  ALA B O   1 
ATOM 3296 C CB  . ALA B 2 94  ? 100.213 124.938 74.854  1.00 172.47 ? 94  ALA B CB  1 
ATOM 3297 N N   . PHE B 2 95  ? 98.693  123.023 77.139  1.00 174.02 ? 95  PHE B N   1 
ATOM 3298 C CA  . PHE B 2 95  ? 98.130  121.710 77.413  1.00 174.02 ? 95  PHE B CA  1 
ATOM 3299 C C   . PHE B 2 95  ? 96.783  121.836 78.112  1.00 174.02 ? 95  PHE B C   1 
ATOM 3300 O O   . PHE B 2 95  ? 95.929  120.950 78.001  1.00 174.02 ? 95  PHE B O   1 
ATOM 3301 C CB  . PHE B 2 95  ? 99.132  120.906 78.246  1.00 174.02 ? 95  PHE B CB  1 
ATOM 3302 C CG  . PHE B 2 95  ? 98.692  119.514 78.561  1.00 174.02 ? 95  PHE B CG  1 
ATOM 3303 C CD1 . PHE B 2 95  ? 98.736  118.533 77.586  1.00 174.02 ? 95  PHE B CD1 1 
ATOM 3304 C CD2 . PHE B 2 95  ? 98.287  119.171 79.842  1.00 174.02 ? 95  PHE B CD2 1 
ATOM 3305 C CE1 . PHE B 2 95  ? 98.347  117.237 77.865  1.00 174.02 ? 95  PHE B CE1 1 
ATOM 3306 C CE2 . PHE B 2 95  ? 97.902  117.875 80.135  1.00 174.02 ? 95  PHE B CE2 1 
ATOM 3307 C CZ  . PHE B 2 95  ? 97.933  116.909 79.142  1.00 174.02 ? 95  PHE B CZ  1 
ATOM 3308 N N   . GLN B 2 96  ? 96.578  122.937 78.838  1.00 172.52 ? 96  GLN B N   1 
ATOM 3309 C CA  . GLN B 2 96  ? 95.225  123.291 79.251  1.00 172.52 ? 96  GLN B CA  1 
ATOM 3310 C C   . GLN B 2 96  ? 94.429  123.844 78.075  1.00 172.52 ? 96  GLN B C   1 
ATOM 3311 O O   . GLN B 2 96  ? 93.199  123.717 78.031  1.00 172.52 ? 96  GLN B O   1 
ATOM 3312 C CB  . GLN B 2 96  ? 95.271  124.289 80.409  1.00 172.52 ? 96  GLN B CB  1 
ATOM 3313 C CG  . GLN B 2 96  ? 93.955  124.451 81.170  1.00 172.52 ? 96  GLN B CG  1 
ATOM 3314 C CD  . GLN B 2 96  ? 93.778  123.457 82.309  1.00 172.52 ? 96  GLN B CD  1 
ATOM 3315 O OE1 . GLN B 2 96  ? 94.371  122.378 82.318  1.00 172.52 ? 96  GLN B OE1 1 
ATOM 3316 N NE2 . GLN B 2 96  ? 92.957  123.827 83.284  1.00 172.52 ? 96  GLN B NE2 1 
ATOM 3317 N N   . ALA B 2 97  ? 95.114  124.443 77.099  1.00 172.97 ? 97  ALA B N   1 
ATOM 3318 C CA  . ALA B 2 97  ? 94.460  124.858 75.863  1.00 172.97 ? 97  ALA B CA  1 
ATOM 3319 C C   . ALA B 2 97  ? 94.462  123.728 74.838  1.00 172.97 ? 97  ALA B C   1 
ATOM 3320 O O   . ALA B 2 97  ? 95.007  123.881 73.739  1.00 172.97 ? 97  ALA B O   1 
ATOM 3321 C CB  . ALA B 2 97  ? 95.141  126.101 75.289  1.00 172.97 ? 97  ALA B CB  1 
ATOM 3322 N N   . HIS B 2 98  ? 93.857  122.589 75.187  1.00 172.31 ? 98  HIS B N   1 
ATOM 3323 C CA  . HIS B 2 98  ? 93.858  121.410 74.334  1.00 172.31 ? 98  HIS B CA  1 
ATOM 3324 C C   . HIS B 2 98  ? 92.467  120.804 74.197  1.00 172.31 ? 98  HIS B C   1 
ATOM 3325 O O   . HIS B 2 98  ? 92.159  120.239 73.141  1.00 172.31 ? 98  HIS B O   1 
ATOM 3326 C CB  . HIS B 2 98  ? 94.821  120.360 74.919  1.00 172.31 ? 98  HIS B CB  1 
ATOM 3327 C CG  . HIS B 2 98  ? 95.220  119.267 73.972  1.00 172.31 ? 98  HIS B CG  1 
ATOM 3328 N ND1 . HIS B 2 98  ? 96.135  118.298 74.323  1.00 172.31 ? 98  HIS B ND1 1 
ATOM 3329 C CD2 . HIS B 2 98  ? 94.934  119.052 72.666  1.00 172.31 ? 98  HIS B CD2 1 
ATOM 3330 C CE1 . HIS B 2 98  ? 96.337  117.491 73.297  1.00 172.31 ? 98  HIS B CE1 1 
ATOM 3331 N NE2 . HIS B 2 98  ? 95.622  117.929 72.277  1.00 172.31 ? 98  HIS B NE2 1 
ATOM 3332 N N   . LYS B 2 99  ? 91.619  120.963 75.228  1.00 169.83 ? 99  LYS B N   1 
ATOM 3333 C CA  . LYS B 2 99  ? 90.261  120.400 75.326  1.00 169.83 ? 99  LYS B CA  1 
ATOM 3334 C C   . LYS B 2 99  ? 90.262  118.875 75.199  1.00 169.83 ? 99  LYS B C   1 
ATOM 3335 O O   . LYS B 2 99  ? 89.779  118.311 74.212  1.00 169.83 ? 99  LYS B O   1 
ATOM 3336 C CB  . LYS B 2 99  ? 89.289  121.043 74.328  1.00 169.83 ? 99  LYS B CB  1 
ATOM 3337 N N   . GLU B 2 100 ? 90.855  118.222 76.209  1.00 172.32 ? 100 GLU B N   1 
ATOM 3338 C CA  . GLU B 2 100 ? 90.714  116.797 76.517  1.00 172.32 ? 100 GLU B CA  1 
ATOM 3339 C C   . GLU B 2 100 ? 91.195  115.846 75.426  1.00 172.32 ? 100 GLU B C   1 
ATOM 3340 O O   . GLU B 2 100 ? 90.389  115.151 74.800  1.00 172.32 ? 100 GLU B O   1 
ATOM 3341 C CB  . GLU B 2 100 ? 89.256  116.473 76.865  1.00 172.32 ? 100 GLU B CB  1 
ATOM 3342 N N   . GLU B 2 101 ? 92.502  115.814 75.182  1.00 172.94 ? 101 GLU B N   1 
ATOM 3343 C CA  . GLU B 2 101 ? 93.065  114.801 74.299  1.00 172.94 ? 101 GLU B CA  1 
ATOM 3344 C C   . GLU B 2 101 ? 94.259  114.119 74.956  1.00 172.94 ? 101 GLU B C   1 
ATOM 3345 O O   . GLU B 2 101 ? 94.726  114.559 76.012  1.00 172.94 ? 101 GLU B O   1 
ATOM 3346 C CB  . GLU B 2 101 ? 93.459  115.415 72.957  1.00 172.94 ? 101 GLU B CB  1 
ATOM 3347 N N   . ASN B 2 102 ? 94.755  113.039 74.342  1.00 171.98 ? 102 ASN B N   1 
ATOM 3348 C CA  . ASN B 2 102 ? 95.821  112.234 74.923  1.00 171.98 ? 102 ASN B CA  1 
ATOM 3349 C C   . ASN B 2 102 ? 97.176  112.432 74.269  1.00 171.98 ? 102 ASN B C   1 
ATOM 3350 O O   . ASN B 2 102 ? 98.165  111.893 74.778  1.00 171.98 ? 102 ASN B O   1 
ATOM 3351 C CB  . ASN B 2 102 ? 95.498  110.739 74.799  1.00 171.98 ? 102 ASN B CB  1 
ATOM 3352 C CG  . ASN B 2 102 ? 94.357  110.307 75.674  1.00 171.98 ? 102 ASN B CG  1 
ATOM 3353 O OD1 . ASN B 2 102 ? 94.243  110.718 76.823  1.00 171.98 ? 102 ASN B OD1 1 
ATOM 3354 N ND2 . ASN B 2 102 ? 93.515  109.436 75.137  1.00 171.98 ? 102 ASN B ND2 1 
ATOM 3355 N N   . TRP B 2 103 ? 97.257  113.160 73.154  1.00 174.45 ? 103 TRP B N   1 
ATOM 3356 C CA  . TRP B 2 103 ? 98.422  113.040 72.285  1.00 174.45 ? 103 TRP B CA  1 
ATOM 3357 C C   . TRP B 2 103 ? 99.550  113.975 72.690  1.00 174.45 ? 103 TRP B C   1 
ATOM 3358 O O   . TRP B 2 103 ? 100.651 113.871 72.140  1.00 174.45 ? 103 TRP B O   1 
ATOM 3359 C CB  . TRP B 2 103 ? 97.977  113.225 70.823  1.00 174.45 ? 103 TRP B CB  1 
ATOM 3360 C CG  . TRP B 2 103 ? 97.544  114.597 70.387  1.00 174.45 ? 103 TRP B CG  1 
ATOM 3361 C CD1 . TRP B 2 103 ? 96.261  114.983 70.148  1.00 174.45 ? 103 TRP B CD1 1 
ATOM 3362 C CD2 . TRP B 2 103 ? 98.371  115.682 69.924  1.00 174.45 ? 103 TRP B CD2 1 
ATOM 3363 N NE1 . TRP B 2 103 ? 96.223  116.273 69.688  1.00 174.45 ? 103 TRP B NE1 1 
ATOM 3364 C CE2 . TRP B 2 103 ? 97.505  116.722 69.528  1.00 174.45 ? 103 TRP B CE2 1 
ATOM 3365 C CE3 . TRP B 2 103 ? 99.752  115.894 69.849  1.00 174.45 ? 103 TRP B CE3 1 
ATOM 3366 C CZ2 . TRP B 2 103 ? 97.972  117.950 69.070  1.00 174.45 ? 103 TRP B CZ2 1 
ATOM 3367 C CZ3 . TRP B 2 103 ? 100.213 117.118 69.398  1.00 174.45 ? 103 TRP B CZ3 1 
ATOM 3368 C CH2 . TRP B 2 103 ? 99.325  118.128 69.012  1.00 174.45 ? 103 TRP B CH2 1 
ATOM 3369 N N   . ALA B 2 104 ? 99.317  114.860 73.659  1.00 171.14 ? 104 ALA B N   1 
ATOM 3370 C CA  . ALA B 2 104 ? 100.408 115.686 74.164  1.00 171.14 ? 104 ALA B CA  1 
ATOM 3371 C C   . ALA B 2 104 ? 101.072 115.051 75.383  1.00 171.14 ? 104 ALA B C   1 
ATOM 3372 O O   . ALA B 2 104 ? 102.042 115.596 75.922  1.00 171.14 ? 104 ALA B O   1 
ATOM 3373 C CB  . ALA B 2 104 ? 99.895  117.086 74.487  1.00 171.14 ? 104 ALA B CB  1 
ATOM 3374 N N   . LEU B 2 105 ? 100.568 113.903 75.831  1.00 165.97 ? 105 LEU B N   1 
ATOM 3375 C CA  . LEU B 2 105 ? 101.140 113.169 76.961  1.00 165.97 ? 105 LEU B CA  1 
ATOM 3376 C C   . LEU B 2 105 ? 102.505 112.514 76.695  1.00 165.97 ? 105 LEU B C   1 
ATOM 3377 O O   . LEU B 2 105 ? 103.271 112.361 77.655  1.00 165.97 ? 105 LEU B O   1 
ATOM 3378 C CB  . LEU B 2 105 ? 100.154 112.113 77.481  1.00 165.97 ? 105 LEU B CB  1 
ATOM 3379 C CG  . LEU B 2 105 ? 99.028  112.472 78.467  1.00 165.97 ? 105 LEU B CG  1 
ATOM 3380 C CD1 . LEU B 2 105 ? 99.610  112.956 79.795  1.00 165.97 ? 105 LEU B CD1 1 
ATOM 3381 C CD2 . LEU B 2 105 ? 97.988  113.458 77.929  1.00 165.97 ? 105 LEU B CD2 1 
ATOM 3382 N N   . PRO B 2 106 ? 102.858 112.066 75.469  1.00 163.92 ? 106 PRO B N   1 
ATOM 3383 C CA  . PRO B 2 106 ? 104.293 111.864 75.189  1.00 163.92 ? 106 PRO B CA  1 
ATOM 3384 C C   . PRO B 2 106 ? 105.146 113.118 75.293  1.00 163.92 ? 106 PRO B C   1 
ATOM 3385 O O   . PRO B 2 106 ? 106.316 113.018 75.682  1.00 163.92 ? 106 PRO B O   1 
ATOM 3386 C CB  . PRO B 2 106 ? 104.290 111.302 73.763  1.00 163.92 ? 106 PRO B CB  1 
ATOM 3387 C CG  . PRO B 2 106 ? 103.070 110.512 73.722  1.00 163.92 ? 106 PRO B CG  1 
ATOM 3388 C CD  . PRO B 2 106 ? 102.053 111.335 74.461  1.00 163.92 ? 106 PRO B CD  1 
ATOM 3389 N N   . VAL B 2 107 ? 104.602 114.296 74.968  1.00 158.91 ? 107 VAL B N   1 
ATOM 3390 C CA  . VAL B 2 107 ? 105.379 115.531 75.072  1.00 158.91 ? 107 VAL B CA  1 
ATOM 3391 C C   . VAL B 2 107 ? 105.495 115.942 76.541  1.00 158.91 ? 107 VAL B C   1 
ATOM 3392 O O   . VAL B 2 107 ? 106.439 116.638 76.945  1.00 158.91 ? 107 VAL B O   1 
ATOM 3393 C CB  . VAL B 2 107 ? 104.735 116.622 74.185  1.00 158.91 ? 107 VAL B CB  1 
ATOM 3394 C CG1 . VAL B 2 107 ? 105.563 117.917 74.118  1.00 158.91 ? 107 VAL B CG1 1 
ATOM 3395 C CG2 . VAL B 2 107 ? 104.475 116.081 72.787  1.00 158.91 ? 107 VAL B CG2 1 
ATOM 3396 N N   . MET B 2 108 ? 104.572 115.445 77.376  1.00 157.00 ? 108 MET B N   1 
ATOM 3397 C CA  . MET B 2 108 ? 104.639 115.646 78.823  1.00 157.00 ? 108 MET B CA  1 
ATOM 3398 C C   . MET B 2 108 ? 105.843 114.917 79.432  1.00 157.00 ? 108 MET B C   1 
ATOM 3399 O O   . MET B 2 108 ? 106.386 115.347 80.458  1.00 157.00 ? 108 MET B O   1 
ATOM 3400 C CB  . MET B 2 108 ? 103.313 115.170 79.442  1.00 157.00 ? 108 MET B CB  1 
ATOM 3401 C CG  . MET B 2 108 ? 103.209 115.094 80.970  1.00 157.00 ? 108 MET B CG  1 
ATOM 3402 S SD  . MET B 2 108 ? 103.303 116.683 81.823  1.00 157.00 ? 108 MET B SD  1 
ATOM 3403 C CE  . MET B 2 108 ? 102.139 117.662 80.879  1.00 157.00 ? 108 MET B CE  1 
ATOM 3404 N N   . TYR B 2 109 ? 106.311 113.850 78.772  1.00 157.01 ? 109 TYR B N   1 
ATOM 3405 C CA  . TYR B 2 109 ? 107.408 113.041 79.303  1.00 157.01 ? 109 TYR B CA  1 
ATOM 3406 C C   . TYR B 2 109 ? 108.746 113.778 79.248  1.00 157.01 ? 109 TYR B C   1 
ATOM 3407 O O   . TYR B 2 109 ? 109.528 113.728 80.203  1.00 157.01 ? 109 TYR B O   1 
ATOM 3408 C CB  . TYR B 2 109 ? 107.503 111.721 78.536  1.00 157.01 ? 109 TYR B CB  1 
ATOM 3409 C CG  . TYR B 2 109 ? 106.451 110.704 78.910  1.00 157.01 ? 109 TYR B CG  1 
ATOM 3410 C CD1 . TYR B 2 109 ? 106.064 110.531 80.233  1.00 157.01 ? 109 TYR B CD1 1 
ATOM 3411 C CD2 . TYR B 2 109 ? 105.843 109.917 77.936  1.00 157.01 ? 109 TYR B CD2 1 
ATOM 3412 C CE1 . TYR B 2 109 ? 105.097 109.602 80.582  1.00 157.01 ? 109 TYR B CE1 1 
ATOM 3413 C CE2 . TYR B 2 109 ? 104.876 108.985 78.271  1.00 157.01 ? 109 TYR B CE2 1 
ATOM 3414 C CZ  . TYR B 2 109 ? 104.508 108.833 79.595  1.00 157.01 ? 109 TYR B CZ  1 
ATOM 3415 O OH  . TYR B 2 109 ? 103.549 107.907 79.930  1.00 157.01 ? 109 TYR B OH  1 
ATOM 3416 N N   . ALA B 2 110 ? 109.030 114.472 78.145  1.00 159.55 ? 110 ALA B N   1 
ATOM 3417 C CA  . ALA B 2 110 ? 110.375 115.010 77.967  1.00 159.55 ? 110 ALA B CA  1 
ATOM 3418 C C   . ALA B 2 110 ? 110.548 116.423 78.509  1.00 159.55 ? 110 ALA B C   1 
ATOM 3419 O O   . ALA B 2 110 ? 111.608 117.017 78.293  1.00 159.55 ? 110 ALA B O   1 
ATOM 3420 C CB  . ALA B 2 110 ? 110.773 114.987 76.493  1.00 159.55 ? 110 ALA B CB  1 
ATOM 3421 N N   . VAL B 2 111 ? 109.551 116.985 79.185  1.00 156.82 ? 111 VAL B N   1 
ATOM 3422 C CA  . VAL B 2 111 ? 109.662 118.314 79.765  1.00 156.82 ? 111 VAL B CA  1 
ATOM 3423 C C   . VAL B 2 111 ? 109.851 118.257 81.275  1.00 156.82 ? 111 VAL B C   1 
ATOM 3424 O O   . VAL B 2 111 ? 110.337 119.216 81.878  1.00 156.82 ? 111 VAL B O   1 
ATOM 3425 C CB  . VAL B 2 111 ? 108.446 119.188 79.391  1.00 156.82 ? 111 VAL B CB  1 
ATOM 3426 C CG1 . VAL B 2 111 ? 108.442 119.469 77.901  1.00 156.82 ? 111 VAL B CG1 1 
ATOM 3427 C CG2 . VAL B 2 111 ? 107.152 118.520 79.808  1.00 156.82 ? 111 VAL B CG2 1 
ATOM 3428 N N   . ALA B 2 112 ? 109.478 117.140 81.905  1.00 151.19 ? 112 ALA B N   1 
ATOM 3429 C CA  . ALA B 2 112 ? 109.638 117.022 83.350  1.00 151.19 ? 112 ALA B CA  1 
ATOM 3430 C C   . ALA B 2 112 ? 110.948 116.332 83.707  1.00 151.19 ? 112 ALA B C   1 
ATOM 3431 O O   . ALA B 2 112 ? 111.592 116.688 84.702  1.00 151.19 ? 112 ALA B O   1 
ATOM 3432 C CB  . ALA B 2 112 ? 108.452 116.268 83.949  1.00 151.19 ? 112 ALA B CB  1 
ATOM 3433 N N   . LEU B 2 113 ? 111.351 115.335 82.914  1.00 155.09 ? 113 LEU B N   1 
ATOM 3434 C CA  . LEU B 2 113 ? 112.580 114.598 83.201  1.00 155.09 ? 113 LEU B CA  1 
ATOM 3435 C C   . LEU B 2 113 ? 113.812 115.442 82.901  1.00 155.09 ? 113 LEU B C   1 
ATOM 3436 O O   . LEU B 2 113 ? 114.823 115.355 83.609  1.00 155.09 ? 113 LEU B O   1 
ATOM 3437 C CB  . LEU B 2 113 ? 112.608 113.297 82.396  1.00 155.09 ? 113 LEU B CB  1 
ATOM 3438 C CG  . LEU B 2 113 ? 113.815 112.363 82.527  1.00 155.09 ? 113 LEU B CG  1 
ATOM 3439 C CD1 . LEU B 2 113 ? 114.077 112.014 83.985  1.00 155.09 ? 113 LEU B CD1 1 
ATOM 3440 C CD2 . LEU B 2 113 ? 113.616 111.104 81.698  1.00 155.09 ? 113 LEU B CD2 1 
ATOM 3441 N N   . ASP B 2 114 ? 113.743 116.277 81.862  1.00 158.25 ? 114 ASP B N   1 
ATOM 3442 C CA  . ASP B 2 114 ? 114.889 117.104 81.505  1.00 158.25 ? 114 ASP B CA  1 
ATOM 3443 C C   . ASP B 2 114 ? 115.055 118.271 82.472  1.00 158.25 ? 114 ASP B C   1 
ATOM 3444 O O   . ASP B 2 114 ? 116.155 118.819 82.607  1.00 158.25 ? 114 ASP B O   1 
ATOM 3445 C CB  . ASP B 2 114 ? 114.747 117.591 80.064  1.00 158.25 ? 114 ASP B CB  1 
ATOM 3446 C CG  . ASP B 2 114 ? 114.628 116.444 79.077  1.00 158.25 ? 114 ASP B CG  1 
ATOM 3447 O OD1 . ASP B 2 114 ? 114.504 116.705 77.864  1.00 158.25 ? 114 ASP B OD1 1 
ATOM 3448 O OD2 . ASP B 2 114 ? 114.660 115.276 79.518  1.00 158.25 ? 114 ASP B OD2 1 
ATOM 3449 N N   . LEU B 2 115 ? 113.978 118.668 83.155  1.00 153.90 ? 115 LEU B N   1 
ATOM 3450 C CA  . LEU B 2 115 ? 114.085 119.587 84.289  1.00 153.90 ? 115 LEU B CA  1 
ATOM 3451 C C   . LEU B 2 115 ? 114.084 118.739 85.566  1.00 153.90 ? 115 LEU B C   1 
ATOM 3452 O O   . LEU B 2 115 ? 113.190 118.786 86.416  1.00 153.90 ? 115 LEU B O   1 
ATOM 3453 C CB  . LEU B 2 115 ? 112.985 120.647 84.226  1.00 153.90 ? 115 LEU B CB  1 
ATOM 3454 C CG  . LEU B 2 115 ? 112.799 121.770 85.261  1.00 153.90 ? 115 LEU B CG  1 
ATOM 3455 C CD1 . LEU B 2 115 ? 113.886 122.825 85.166  1.00 153.90 ? 115 LEU B CD1 1 
ATOM 3456 C CD2 . LEU B 2 115 ? 111.443 122.390 85.054  1.00 153.90 ? 115 LEU B CD2 1 
ATOM 3457 N N   . ARG B 2 116 ? 115.077 117.859 85.645  1.00 148.63 ? 116 ARG B N   1 
ATOM 3458 C CA  . ARG B 2 116 ? 115.452 117.224 86.898  1.00 148.63 ? 116 ARG B CA  1 
ATOM 3459 C C   . ARG B 2 116 ? 116.969 117.287 86.996  1.00 148.63 ? 116 ARG B C   1 
ATOM 3460 O O   . ARG B 2 116 ? 117.518 117.532 88.072  1.00 148.63 ? 116 ARG B O   1 
ATOM 3461 C CB  . ARG B 2 116 ? 114.908 115.790 86.951  1.00 148.63 ? 116 ARG B CB  1 
ATOM 3462 C CG  . ARG B 2 116 ? 114.806 115.091 88.331  1.00 148.63 ? 116 ARG B CG  1 
ATOM 3463 C CD  . ARG B 2 116 ? 116.127 114.597 88.960  1.00 148.63 ? 116 ARG B CD  1 
ATOM 3464 N NE  . ARG B 2 116 ? 117.129 114.153 87.990  1.00 148.63 ? 116 ARG B NE  1 
ATOM 3465 C CZ  . ARG B 2 116 ? 117.081 113.038 87.266  1.00 148.63 ? 116 ARG B CZ  1 
ATOM 3466 N NH1 . ARG B 2 116 ? 116.094 112.165 87.391  1.00 148.63 ? 116 ARG B NH1 1 
ATOM 3467 N NH2 . ARG B 2 116 ? 118.057 112.789 86.398  1.00 148.63 ? 116 ARG B NH2 1 
ATOM 3468 N N   . VAL B 2 117 ? 117.651 117.073 85.869  1.00 152.88 ? 117 VAL B N   1 
ATOM 3469 C CA  . VAL B 2 117 ? 119.110 117.066 85.878  1.00 152.88 ? 117 VAL B CA  1 
ATOM 3470 C C   . VAL B 2 117 ? 119.643 118.476 85.633  1.00 152.88 ? 117 VAL B C   1 
ATOM 3471 O O   . VAL B 2 117 ? 120.715 118.849 86.128  1.00 152.88 ? 117 VAL B O   1 
ATOM 3472 C CB  . VAL B 2 117 ? 119.640 116.020 84.866  1.00 152.88 ? 117 VAL B CB  1 
ATOM 3473 C CG1 . VAL B 2 117 ? 119.253 116.344 83.418  1.00 152.88 ? 117 VAL B CG1 1 
ATOM 3474 C CG2 . VAL B 2 117 ? 121.148 115.794 85.010  1.00 152.88 ? 117 VAL B CG2 1 
ATOM 3475 N N   . PHE B 2 118 ? 118.876 119.304 84.919  1.00 156.02 ? 118 PHE B N   1 
ATOM 3476 C CA  . PHE B 2 118 ? 119.237 120.710 84.792  1.00 156.02 ? 118 PHE B CA  1 
ATOM 3477 C C   . PHE B 2 118 ? 118.752 121.505 85.998  1.00 156.02 ? 118 PHE B C   1 
ATOM 3478 O O   . PHE B 2 118 ? 119.287 122.579 86.298  1.00 156.02 ? 118 PHE B O   1 
ATOM 3479 C CB  . PHE B 2 118 ? 118.671 121.281 83.493  1.00 156.02 ? 118 PHE B CB  1 
ATOM 3480 C CG  . PHE B 2 118 ? 119.545 121.038 82.295  1.00 156.02 ? 118 PHE B CG  1 
ATOM 3481 C CD1 . PHE B 2 118 ? 120.814 121.596 82.222  1.00 156.02 ? 118 PHE B CD1 1 
ATOM 3482 C CD2 . PHE B 2 118 ? 119.103 120.240 81.248  1.00 156.02 ? 118 PHE B CD2 1 
ATOM 3483 C CE1 . PHE B 2 118 ? 121.626 121.373 81.120  1.00 156.02 ? 118 PHE B CE1 1 
ATOM 3484 C CE2 . PHE B 2 118 ? 119.907 120.012 80.141  1.00 156.02 ? 118 PHE B CE2 1 
ATOM 3485 C CZ  . PHE B 2 118 ? 121.170 120.579 80.078  1.00 156.02 ? 118 PHE B CZ  1 
ATOM 3486 N N   . ALA B 2 119 ? 117.743 120.992 86.698  1.00 154.54 ? 119 ALA B N   1 
ATOM 3487 C CA  . ALA B 2 119 ? 117.239 121.601 87.920  1.00 154.54 ? 119 ALA B CA  1 
ATOM 3488 C C   . ALA B 2 119 ? 118.090 121.264 89.138  1.00 154.54 ? 119 ALA B C   1 
ATOM 3489 O O   . ALA B 2 119 ? 118.074 122.017 90.118  1.00 154.54 ? 119 ALA B O   1 
ATOM 3490 C CB  . ALA B 2 119 ? 115.791 121.171 88.163  1.00 154.54 ? 119 ALA B CB  1 
ATOM 3491 N N   . ASN B 2 120 ? 118.822 120.153 89.103  1.00 151.65 ? 120 ASN B N   1 
ATOM 3492 C CA  . ASN B 2 120 ? 119.739 119.780 90.171  1.00 151.65 ? 120 ASN B CA  1 
ATOM 3493 C C   . ASN B 2 120 ? 121.079 120.494 90.061  1.00 151.65 ? 120 ASN B C   1 
ATOM 3494 O O   . ASN B 2 120 ? 121.760 120.670 91.077  1.00 151.65 ? 120 ASN B O   1 
ATOM 3495 C CB  . ASN B 2 120 ? 119.956 118.259 90.165  1.00 151.65 ? 120 ASN B CB  1 
ATOM 3496 C CG  . ASN B 2 120 ? 120.682 117.759 91.399  1.00 151.65 ? 120 ASN B CG  1 
ATOM 3497 O OD1 . ASN B 2 120 ? 120.514 118.296 92.493  1.00 151.65 ? 120 ASN B OD1 1 
ATOM 3498 N ND2 . ASN B 2 120 ? 121.495 116.724 91.226  1.00 151.65 ? 120 ASN B ND2 1 
ATOM 3499 N N   . ASN B 2 121 ? 121.458 120.938 88.866  1.00 152.26 ? 121 ASN B N   1 
ATOM 3500 C CA  . ASN B 2 121 ? 122.777 121.513 88.621  1.00 152.26 ? 121 ASN B CA  1 
ATOM 3501 C C   . ASN B 2 121 ? 122.638 123.023 88.466  1.00 152.26 ? 121 ASN B C   1 
ATOM 3502 O O   . ASN B 2 121 ? 122.540 123.537 87.347  1.00 152.26 ? 121 ASN B O   1 
ATOM 3503 C CB  . ASN B 2 121 ? 123.416 120.889 87.385  1.00 152.26 ? 121 ASN B CB  1 
ATOM 3504 C CG  . ASN B 2 121 ? 123.641 119.400 87.536  1.00 152.26 ? 121 ASN B CG  1 
ATOM 3505 O OD1 . ASN B 2 121 ? 124.043 118.926 88.598  1.00 152.26 ? 121 ASN B OD1 1 
ATOM 3506 N ND2 . ASN B 2 121 ? 123.381 118.651 86.471  1.00 152.26 ? 121 ASN B ND2 1 
ATOM 3507 N N   . ALA B 2 122 ? 122.621 123.734 89.600  1.00 153.53 ? 122 ALA B N   1 
ATOM 3508 C CA  . ALA B 2 122 ? 122.769 125.185 89.569  1.00 153.53 ? 122 ALA B CA  1 
ATOM 3509 C C   . ALA B 2 122 ? 123.617 125.688 90.734  1.00 153.53 ? 122 ALA B C   1 
ATOM 3510 O O   . ALA B 2 122 ? 123.503 126.863 91.102  1.00 153.53 ? 122 ALA B O   1 
ATOM 3511 C CB  . ALA B 2 122 ? 121.403 125.877 89.574  1.00 153.53 ? 122 ALA B CB  1 
ATOM 3512 N N   . ASP B 2 123 ? 124.452 124.838 91.323  1.00 153.27 ? 123 ASP B N   1 
ATOM 3513 C CA  . ASP B 2 123 ? 125.292 125.225 92.447  1.00 153.27 ? 123 ASP B CA  1 
ATOM 3514 C C   . ASP B 2 123 ? 126.706 125.560 91.984  1.00 153.27 ? 123 ASP B C   1 
ATOM 3515 O O   . ASP B 2 123 ? 127.181 125.033 90.978  1.00 153.27 ? 123 ASP B O   1 
ATOM 3516 C CB  . ASP B 2 123 ? 125.328 124.109 93.494  1.00 153.27 ? 123 ASP B CB  1 
ATOM 3517 C CG  . ASP B 2 123 ? 125.550 122.739 92.879  1.00 153.27 ? 123 ASP B CG  1 
ATOM 3518 O OD1 . ASP B 2 123 ? 125.496 122.626 91.636  1.00 153.27 ? 123 ASP B OD1 1 
ATOM 3519 O OD2 . ASP B 2 123 ? 125.780 121.775 93.638  1.00 153.27 ? 123 ASP B OD2 1 
ATOM 3520 N N   . GLY B 2 135 ? 119.801 123.525 99.208  1.00 145.78 ? 135 GLY B N   1 
ATOM 3521 C CA  . GLY B 2 135 ? 119.676 124.524 98.163  1.00 145.78 ? 135 GLY B CA  1 
ATOM 3522 C C   . GLY B 2 135 ? 118.262 125.044 97.999  1.00 145.78 ? 135 GLY B C   1 
ATOM 3523 O O   . GLY B 2 135 ? 117.303 124.418 98.452  1.00 145.78 ? 135 GLY B O   1 
ATOM 3524 N N   . ASP B 2 136 ? 118.135 126.196 97.341  1.00 150.93 ? 136 ASP B N   1 
ATOM 3525 C CA  . ASP B 2 136 ? 116.844 126.833 97.113  1.00 150.93 ? 136 ASP B CA  1 
ATOM 3526 C C   . ASP B 2 136 ? 116.349 126.713 95.673  1.00 150.93 ? 136 ASP B C   1 
ATOM 3527 O O   . ASP B 2 136 ? 115.144 126.848 95.430  1.00 150.93 ? 136 ASP B O   1 
ATOM 3528 C CB  . ASP B 2 136 ? 116.889 128.301 97.576  1.00 150.93 ? 136 ASP B CB  1 
ATOM 3529 C CG  . ASP B 2 136 ? 117.722 129.220 96.668  1.00 150.93 ? 136 ASP B CG  1 
ATOM 3530 O OD1 . ASP B 2 136 ? 117.595 130.448 96.849  1.00 150.93 ? 136 ASP B OD1 1 
ATOM 3531 O OD2 . ASP B 2 136 ? 118.582 128.762 95.878  1.00 150.93 ? 136 ASP B OD2 1 
ATOM 3532 N N   . MET B 2 137 ? 117.249 126.452 94.717  1.00 149.92 ? 137 MET B N   1 
ATOM 3533 C CA  . MET B 2 137 ? 116.831 126.270 93.329  1.00 149.92 ? 137 MET B CA  1 
ATOM 3534 C C   . MET B 2 137 ? 116.088 124.949 93.156  1.00 149.92 ? 137 MET B C   1 
ATOM 3535 O O   . MET B 2 137 ? 115.211 124.820 92.294  1.00 149.92 ? 137 MET B O   1 
ATOM 3536 C CB  . MET B 2 137 ? 118.047 126.367 92.394  1.00 149.92 ? 137 MET B CB  1 
ATOM 3537 C CG  . MET B 2 137 ? 118.918 125.114 92.244  1.00 149.92 ? 137 MET B CG  1 
ATOM 3538 S SD  . MET B 2 137 ? 119.532 124.441 93.801  1.00 149.92 ? 137 MET B SD  1 
ATOM 3539 C CE  . MET B 2 137 ? 120.760 125.665 94.240  1.00 149.92 ? 137 MET B CE  1 
ATOM 3540 N N   . LEU B 2 138 ? 116.383 123.976 94.022  1.00 143.80 ? 138 LEU B N   1 
ATOM 3541 C CA  . LEU B 2 138 ? 115.701 122.694 93.972  1.00 143.80 ? 138 LEU B CA  1 
ATOM 3542 C C   . LEU B 2 138 ? 114.289 122.820 94.534  1.00 143.80 ? 138 LEU B C   1 
ATOM 3543 O O   . LEU B 2 138 ? 113.349 122.225 93.996  1.00 143.80 ? 138 LEU B O   1 
ATOM 3544 C CB  . LEU B 2 138 ? 116.548 121.668 94.729  1.00 143.80 ? 138 LEU B CB  1 
ATOM 3545 C CG  . LEU B 2 138 ? 116.277 120.171 94.663  1.00 143.80 ? 138 LEU B CG  1 
ATOM 3546 C CD1 . LEU B 2 138 ? 116.412 119.678 93.231  1.00 143.80 ? 138 LEU B CD1 1 
ATOM 3547 C CD2 . LEU B 2 138 ? 117.231 119.415 95.569  1.00 143.80 ? 138 LEU B CD2 1 
ATOM 3548 N N   . GLU B 2 139 ? 114.114 123.659 95.561  1.00 150.15 ? 139 GLU B N   1 
ATOM 3549 C CA  . GLU B 2 139 ? 112.782 123.988 96.066  1.00 150.15 ? 139 GLU B CA  1 
ATOM 3550 C C   . GLU B 2 139 ? 112.001 124.831 95.060  1.00 150.15 ? 139 GLU B C   1 
ATOM 3551 O O   . GLU B 2 139 ? 110.774 124.696 94.946  1.00 150.15 ? 139 GLU B O   1 
ATOM 3552 C CB  . GLU B 2 139 ? 112.913 124.713 97.415  1.00 150.15 ? 139 GLU B CB  1 
ATOM 3553 C CG  . GLU B 2 139 ? 111.709 125.535 97.983  1.00 150.15 ? 139 GLU B CG  1 
ATOM 3554 C CD  . GLU B 2 139 ? 110.337 124.838 98.054  1.00 150.15 ? 139 GLU B CD  1 
ATOM 3555 O OE1 . GLU B 2 139 ? 109.346 125.568 98.269  1.00 150.15 ? 139 GLU B OE1 1 
ATOM 3556 O OE2 . GLU B 2 139 ? 110.225 123.593 98.005  1.00 150.15 ? 139 GLU B OE2 1 
ATOM 3557 N N   . LYS B 2 140 ? 112.700 125.699 94.317  1.00 154.26 ? 140 LYS B N   1 
ATOM 3558 C CA  . LYS B 2 140 ? 112.058 126.497 93.273  1.00 154.26 ? 140 LYS B CA  1 
ATOM 3559 C C   . LYS B 2 140 ? 111.549 125.615 92.137  1.00 154.26 ? 140 LYS B C   1 
ATOM 3560 O O   . LYS B 2 140 ? 110.418 125.786 91.658  1.00 154.26 ? 140 LYS B O   1 
ATOM 3561 C CB  . LYS B 2 140 ? 113.043 127.544 92.748  1.00 154.26 ? 140 LYS B CB  1 
ATOM 3562 C CG  . LYS B 2 140 ? 112.536 128.358 91.564  1.00 154.26 ? 140 LYS B CG  1 
ATOM 3563 C CD  . LYS B 2 140 ? 113.162 129.751 91.513  1.00 154.26 ? 140 LYS B CD  1 
ATOM 3564 C CE  . LYS B 2 140 ? 113.079 130.477 92.851  1.00 154.26 ? 140 LYS B CE  1 
ATOM 3565 N NZ  . LYS B 2 140 ? 113.841 131.755 92.833  1.00 154.26 ? 140 LYS B NZ  1 
ATOM 3566 N N   . ALA B 2 141 ? 112.363 124.637 91.722  1.00 151.75 ? 141 ALA B N   1 
ATOM 3567 C CA  . ALA B 2 141 ? 111.927 123.660 90.727  1.00 151.75 ? 141 ALA B CA  1 
ATOM 3568 C C   . ALA B 2 141 ? 110.807 122.777 91.267  1.00 151.75 ? 141 ALA B C   1 
ATOM 3569 O O   . ALA B 2 141 ? 109.905 122.386 90.516  1.00 151.75 ? 141 ALA B O   1 
ATOM 3570 C CB  . ALA B 2 141 ? 113.112 122.809 90.274  1.00 151.75 ? 141 ALA B CB  1 
ATOM 3571 N N   . ALA B 2 142 ? 110.832 122.495 92.578  1.00 148.72 ? 142 ALA B N   1 
ATOM 3572 C CA  . ALA B 2 142 ? 109.764 121.737 93.226  1.00 148.72 ? 142 ALA B CA  1 
ATOM 3573 C C   . ALA B 2 142 ? 108.428 122.468 93.181  1.00 148.72 ? 142 ALA B C   1 
ATOM 3574 O O   . ALA B 2 142 ? 107.401 121.854 92.879  1.00 148.72 ? 142 ALA B O   1 
ATOM 3575 C CB  . ALA B 2 142 ? 110.137 121.439 94.675  1.00 148.72 ? 142 ALA B CB  1 
ATOM 3576 N N   . GLU B 2 143 ? 108.416 123.775 93.458  1.00 151.64 ? 143 GLU B N   1 
ATOM 3577 C CA  . GLU B 2 143 ? 107.139 124.489 93.457  1.00 151.64 ? 143 GLU B CA  1 
ATOM 3578 C C   . GLU B 2 143 ? 106.647 124.749 92.033  1.00 151.64 ? 143 GLU B C   1 
ATOM 3579 O O   . GLU B 2 143 ? 105.439 124.679 91.766  1.00 151.64 ? 143 GLU B O   1 
ATOM 3580 C CB  . GLU B 2 143 ? 107.215 125.787 94.274  1.00 151.64 ? 143 GLU B CB  1 
ATOM 3581 C CG  . GLU B 2 143 ? 108.340 126.749 93.957  1.00 151.64 ? 143 GLU B CG  1 
ATOM 3582 C CD  . GLU B 2 143 ? 107.985 127.764 92.884  1.00 151.64 ? 143 GLU B CD  1 
ATOM 3583 O OE1 . GLU B 2 143 ? 106.795 127.861 92.515  1.00 151.64 ? 143 GLU B OE1 1 
ATOM 3584 O OE2 . GLU B 2 143 ? 108.901 128.466 92.407  1.00 151.64 ? 143 GLU B OE2 1 
ATOM 3585 N N   . LEU B 2 144 ? 107.564 124.983 91.080  1.00 151.64 ? 144 LEU B N   1 
ATOM 3586 C CA  . LEU B 2 144 ? 107.085 125.213 89.715  1.00 151.64 ? 144 LEU B CA  1 
ATOM 3587 C C   . LEU B 2 144 ? 106.734 123.899 89.015  1.00 151.64 ? 144 LEU B C   1 
ATOM 3588 O O   . LEU B 2 144 ? 106.070 123.909 87.972  1.00 151.64 ? 144 LEU B O   1 
ATOM 3589 C CB  . LEU B 2 144 ? 108.100 126.027 88.898  1.00 151.64 ? 144 LEU B CB  1 
ATOM 3590 C CG  . LEU B 2 144 ? 109.532 125.625 88.513  1.00 151.64 ? 144 LEU B CG  1 
ATOM 3591 C CD1 . LEU B 2 144 ? 109.616 124.788 87.245  1.00 151.64 ? 144 LEU B CD1 1 
ATOM 3592 C CD2 . LEU B 2 144 ? 110.432 126.852 88.415  1.00 151.64 ? 144 LEU B CD2 1 
ATOM 3593 N N   . LEU B 2 145 ? 107.167 122.758 89.566  1.00 149.08 ? 145 LEU B N   1 
ATOM 3594 C CA  . LEU B 2 145 ? 106.711 121.477 89.037  1.00 149.08 ? 145 LEU B CA  1 
ATOM 3595 C C   . LEU B 2 145 ? 105.464 120.994 89.775  1.00 149.08 ? 145 LEU B C   1 
ATOM 3596 O O   . LEU B 2 145 ? 104.670 120.223 89.222  1.00 149.08 ? 145 LEU B O   1 
ATOM 3597 C CB  . LEU B 2 145 ? 107.853 120.460 89.120  1.00 149.08 ? 145 LEU B CB  1 
ATOM 3598 C CG  . LEU B 2 145 ? 107.697 119.039 88.575  1.00 149.08 ? 145 LEU B CG  1 
ATOM 3599 C CD1 . LEU B 2 145 ? 107.453 119.079 87.079  1.00 149.08 ? 145 LEU B CD1 1 
ATOM 3600 C CD2 . LEU B 2 145 ? 108.935 118.218 88.887  1.00 149.08 ? 145 LEU B CD2 1 
ATOM 3601 N N   . MET B 2 146 ? 105.274 121.451 91.016  1.00 155.95 ? 146 MET B N   1 
ATOM 3602 C CA  . MET B 2 146 ? 104.014 121.254 91.724  1.00 155.95 ? 146 MET B CA  1 
ATOM 3603 C C   . MET B 2 146 ? 102.888 122.038 91.062  1.00 155.95 ? 146 MET B C   1 
ATOM 3604 O O   . MET B 2 146 ? 101.731 121.592 91.044  1.00 155.95 ? 146 MET B O   1 
ATOM 3605 C CB  . MET B 2 146 ? 104.193 121.677 93.183  1.00 155.95 ? 146 MET B CB  1 
ATOM 3606 C CG  . MET B 2 146 ? 103.078 121.308 94.144  1.00 155.95 ? 146 MET B CG  1 
ATOM 3607 S SD  . MET B 2 146 ? 102.633 119.568 94.222  1.00 155.95 ? 146 MET B SD  1 
ATOM 3608 C CE  . MET B 2 146 ? 100.859 119.719 94.416  1.00 155.95 ? 146 MET B CE  1 
ATOM 3609 N N   . SER B 2 147 ? 103.220 123.206 90.499  1.00 162.10 ? 147 SER B N   1 
ATOM 3610 C CA  . SER B 2 147 ? 102.254 123.973 89.715  1.00 162.10 ? 147 SER B CA  1 
ATOM 3611 C C   . SER B 2 147 ? 101.873 123.241 88.430  1.00 162.10 ? 147 SER B C   1 
ATOM 3612 O O   . SER B 2 147 ? 100.764 123.414 87.914  1.00 162.10 ? 147 SER B O   1 
ATOM 3613 C CB  . SER B 2 147 ? 102.819 125.358 89.398  1.00 162.10 ? 147 SER B CB  1 
ATOM 3614 O OG  . SER B 2 147 ? 101.985 126.052 88.486  1.00 162.10 ? 147 SER B OG  1 
ATOM 3615 N N   . CYS B 2 148 ? 102.785 122.424 87.894  1.00 155.61 ? 148 CYS B N   1 
ATOM 3616 C CA  . CYS B 2 148 ? 102.443 121.579 86.753  1.00 155.61 ? 148 CYS B CA  1 
ATOM 3617 C C   . CYS B 2 148 ? 101.488 120.458 87.154  1.00 155.61 ? 148 CYS B C   1 
ATOM 3618 O O   . CYS B 2 148 ? 100.535 120.152 86.427  1.00 155.61 ? 148 CYS B O   1 
ATOM 3619 C CB  . CYS B 2 148 ? 103.716 121.004 86.128  1.00 155.61 ? 148 CYS B CB  1 
ATOM 3620 S SG  . CYS B 2 148 ? 103.512 120.347 84.458  1.00 155.61 ? 148 CYS B SG  1 
ATOM 3621 N N   . PHE B 2 149 ? 101.722 119.849 88.321  1.00 151.97 ? 149 PHE B N   1 
ATOM 3622 C CA  . PHE B 2 149 ? 100.911 118.719 88.769  1.00 151.97 ? 149 PHE B CA  1 
ATOM 3623 C C   . PHE B 2 149 ? 99.506  119.159 89.173  1.00 151.97 ? 149 PHE B C   1 
ATOM 3624 O O   . PHE B 2 149 ? 98.528  118.436 88.942  1.00 151.97 ? 149 PHE B O   1 
ATOM 3625 C CB  . PHE B 2 149 ? 101.612 118.002 89.926  1.00 151.97 ? 149 PHE B CB  1 
ATOM 3626 C CG  . PHE B 2 149 ? 100.759 116.968 90.609  1.00 151.97 ? 149 PHE B CG  1 
ATOM 3627 C CD1 . PHE B 2 149 ? 100.293 115.859 89.916  1.00 151.97 ? 149 PHE B CD1 1 
ATOM 3628 C CD2 . PHE B 2 149 ? 100.427 117.104 91.949  1.00 151.97 ? 149 PHE B CD2 1 
ATOM 3629 C CE1 . PHE B 2 149 ? 99.506  114.910 90.549  1.00 151.97 ? 149 PHE B CE1 1 
ATOM 3630 C CE2 . PHE B 2 149 ? 99.642  116.158 92.592  1.00 151.97 ? 149 PHE B CE2 1 
ATOM 3631 C CZ  . PHE B 2 149 ? 99.182  115.060 91.887  1.00 151.97 ? 149 PHE B CZ  1 
ATOM 3632 N N   . ARG B 2 150 ? 99.384  120.366 89.745  1.00 160.90 ? 150 ARG B N   1 
ATOM 3633 C CA  . ARG B 2 150 ? 98.078  120.848 90.198  1.00 160.90 ? 150 ARG B CA  1 
ATOM 3634 C C   . ARG B 2 150 ? 97.165  121.222 89.030  1.00 160.90 ? 150 ARG B C   1 
ATOM 3635 O O   . ARG B 2 150 ? 95.945  121.334 89.198  1.00 160.90 ? 150 ARG B O   1 
ATOM 3636 C CB  . ARG B 2 150 ? 98.248  122.039 91.147  1.00 160.90 ? 150 ARG B CB  1 
ATOM 3637 C CG  . ARG B 2 150 ? 98.569  123.361 90.462  1.00 160.90 ? 150 ARG B CG  1 
ATOM 3638 C CD  . ARG B 2 150 ? 98.719  124.508 91.454  1.00 160.90 ? 150 ARG B CD  1 
ATOM 3639 N NE  . ARG B 2 150 ? 99.918  124.404 92.276  1.00 160.90 ? 150 ARG B NE  1 
ATOM 3640 C CZ  . ARG B 2 150 ? 99.917  124.100 93.566  1.00 160.90 ? 150 ARG B CZ  1 
ATOM 3641 N NH1 . ARG B 2 150 ? 98.793  123.846 94.216  1.00 160.90 ? 150 ARG B NH1 1 
ATOM 3642 N NH2 . ARG B 2 150 ? 101.072 124.055 94.224  1.00 160.90 ? 150 ARG B NH2 1 
ATOM 3643 N N   . VAL B 2 151 ? 97.735  121.417 87.838  1.00 165.04 ? 151 VAL B N   1 
ATOM 3644 C CA  . VAL B 2 151 ? 96.928  121.619 86.641  1.00 165.04 ? 151 VAL B CA  1 
ATOM 3645 C C   . VAL B 2 151 ? 96.745  120.310 85.877  1.00 165.04 ? 151 VAL B C   1 
ATOM 3646 O O   . VAL B 2 151 ? 95.676  120.083 85.292  1.00 165.04 ? 151 VAL B O   1 
ATOM 3647 C CB  . VAL B 2 151 ? 97.575  122.732 85.793  1.00 165.04 ? 151 VAL B CB  1 
ATOM 3648 C CG1 . VAL B 2 151 ? 96.751  123.070 84.560  1.00 165.04 ? 151 VAL B CG1 1 
ATOM 3649 C CG2 . VAL B 2 151 ? 97.750  123.983 86.636  1.00 165.04 ? 151 VAL B CG2 1 
ATOM 3650 N N   . CYS B 2 152 ? 97.740  119.415 85.918  1.00 157.98 ? 152 CYS B N   1 
ATOM 3651 C CA  . CYS B 2 152 ? 97.638  118.138 85.215  1.00 157.98 ? 152 CYS B CA  1 
ATOM 3652 C C   . CYS B 2 152 ? 96.634  117.192 85.871  1.00 157.98 ? 152 CYS B C   1 
ATOM 3653 O O   . CYS B 2 152 ? 95.961  116.428 85.169  1.00 157.98 ? 152 CYS B O   1 
ATOM 3654 C CB  . CYS B 2 152 ? 99.019  117.484 85.139  1.00 157.98 ? 152 CYS B CB  1 
ATOM 3655 S SG  . CYS B 2 152 ? 99.070  115.838 84.389  1.00 157.98 ? 152 CYS B SG  1 
ATOM 3656 N N   . ALA B 2 153 ? 96.489  117.245 87.198  1.00 156.95 ? 153 ALA B N   1 
ATOM 3657 C CA  . ALA B 2 153 ? 95.669  116.250 87.884  1.00 156.95 ? 153 ALA B CA  1 
ATOM 3658 C C   . ALA B 2 153 ? 94.191  116.619 87.947  1.00 156.95 ? 153 ALA B C   1 
ATOM 3659 O O   . ALA B 2 153 ? 93.415  115.906 88.593  1.00 156.95 ? 153 ALA B O   1 
ATOM 3660 C CB  . ALA B 2 153 ? 96.199  116.025 89.302  1.00 156.95 ? 153 ALA B CB  1 
ATOM 3661 N N   . SER B 2 154 ? 93.776  117.711 87.302  1.00 162.28 ? 154 SER B N   1 
ATOM 3662 C CA  . SER B 2 154 ? 92.414  118.221 87.443  1.00 162.28 ? 154 SER B CA  1 
ATOM 3663 C C   . SER B 2 154 ? 91.424  117.550 86.494  1.00 162.28 ? 154 SER B C   1 
ATOM 3664 O O   . SER B 2 154 ? 90.463  116.917 86.941  1.00 162.28 ? 154 SER B O   1 
ATOM 3665 C CB  . SER B 2 154 ? 92.403  119.739 87.225  1.00 162.28 ? 154 SER B CB  1 
ATOM 3666 O OG  . SER B 2 154 ? 92.738  120.062 85.886  1.00 162.28 ? 154 SER B OG  1 
ATOM 3667 N N   . ASP B 2 155 ? 91.643  117.673 85.187  1.00 158.76 ? 155 ASP B N   1 
ATOM 3668 C CA  . ASP B 2 155 ? 90.624  117.293 84.220  1.00 158.76 ? 155 ASP B CA  1 
ATOM 3669 C C   . ASP B 2 155 ? 90.812  115.840 83.780  1.00 158.76 ? 155 ASP B C   1 
ATOM 3670 O O   . ASP B 2 155 ? 91.875  115.236 83.946  1.00 158.76 ? 155 ASP B O   1 
ATOM 3671 C CB  . ASP B 2 155 ? 90.662  118.240 83.022  1.00 158.76 ? 155 ASP B CB  1 
ATOM 3672 C CG  . ASP B 2 155 ? 89.327  118.335 82.302  1.00 158.76 ? 155 ASP B CG  1 
ATOM 3673 O OD1 . ASP B 2 155 ? 88.727  119.431 82.305  1.00 158.76 ? 155 ASP B OD1 1 
ATOM 3674 O OD2 . ASP B 2 155 ? 88.880  117.320 81.728  1.00 158.76 ? 155 ASP B OD2 1 
ATOM 3675 N N   . THR B 2 156 ? 89.748  115.277 83.214  1.00 161.31 ? 156 THR B N   1 
ATOM 3676 C CA  . THR B 2 156 ? 89.786  113.944 82.630  1.00 161.31 ? 156 THR B CA  1 
ATOM 3677 C C   . THR B 2 156 ? 90.134  114.029 81.150  1.00 161.31 ? 156 THR B C   1 
ATOM 3678 O O   . THR B 2 156 ? 89.290  114.381 80.324  1.00 161.31 ? 156 THR B O   1 
ATOM 3679 C CB  . THR B 2 156 ? 88.440  113.212 82.792  1.00 161.31 ? 156 THR B CB  1 
ATOM 3680 O OG1 . THR B 2 156 ? 87.960  113.376 84.132  1.00 161.31 ? 156 THR B OG1 1 
ATOM 3681 C CG2 . THR B 2 156 ? 88.597  111.730 82.490  1.00 161.31 ? 156 THR B CG2 1 
ATOM 3682 N N   . ILE B 2 160 ? 87.007  107.179 78.867  1.00 175.06 ? 160 ILE B N   1 
ATOM 3683 C CA  . ILE B 2 160 ? 88.038  106.831 79.835  1.00 175.06 ? 160 ILE B CA  1 
ATOM 3684 C C   . ILE B 2 160 ? 89.376  106.879 79.094  1.00 175.06 ? 160 ILE B C   1 
ATOM 3685 O O   . ILE B 2 160 ? 90.451  106.881 79.700  1.00 175.06 ? 160 ILE B O   1 
ATOM 3686 C CB  . ILE B 2 160 ? 87.745  105.449 80.485  1.00 175.06 ? 160 ILE B CB  1 
ATOM 3687 C CG1 . ILE B 2 160 ? 88.539  105.250 81.782  1.00 175.06 ? 160 ILE B CG1 1 
ATOM 3688 C CG2 . ILE B 2 160 ? 88.023  104.316 79.507  1.00 175.06 ? 160 ILE B CG2 1 
ATOM 3689 C CD1 . ILE B 2 160 ? 88.143  106.194 82.901  1.00 175.06 ? 160 ILE B CD1 1 
ATOM 3690 N N   . GLU B 2 161 ? 89.291  106.957 77.763  1.00 177.00 ? 161 GLU B N   1 
ATOM 3691 C CA  . GLU B 2 161 ? 90.496  107.028 76.944  1.00 177.00 ? 161 GLU B CA  1 
ATOM 3692 C C   . GLU B 2 161 ? 91.133  108.410 77.026  1.00 177.00 ? 161 GLU B C   1 
ATOM 3693 O O   . GLU B 2 161 ? 92.329  108.538 77.319  1.00 177.00 ? 161 GLU B O   1 
ATOM 3694 C CB  . GLU B 2 161 ? 90.170  106.670 75.493  1.00 177.00 ? 161 GLU B CB  1 
ATOM 3695 C CG  . GLU B 2 161 ? 89.978  105.179 75.230  1.00 177.00 ? 161 GLU B CG  1 
ATOM 3696 C CD  . GLU B 2 161 ? 90.957  104.301 75.986  1.00 177.00 ? 161 GLU B CD  1 
ATOM 3697 O OE1 . GLU B 2 161 ? 90.541  103.663 76.976  1.00 177.00 ? 161 GLU B OE1 1 
ATOM 3698 O OE2 . GLU B 2 161 ? 92.138  104.237 75.585  1.00 177.00 ? 161 GLU B OE2 1 
ATOM 3699 N N   . ASP B 2 162 ? 90.350  109.458 76.772  1.00 174.16 ? 162 ASP B N   1 
ATOM 3700 C CA  . ASP B 2 162 ? 90.875  110.822 76.752  1.00 174.16 ? 162 ASP B CA  1 
ATOM 3701 C C   . ASP B 2 162 ? 90.997  111.316 78.187  1.00 174.16 ? 162 ASP B C   1 
ATOM 3702 O O   . ASP B 2 162 ? 90.119  112.019 78.697  1.00 174.16 ? 162 ASP B O   1 
ATOM 3703 C CB  . ASP B 2 162 ? 89.991  111.731 75.909  1.00 174.16 ? 162 ASP B CB  1 
ATOM 3704 C CG  . ASP B 2 162 ? 90.096  111.431 74.435  1.00 174.16 ? 162 ASP B CG  1 
ATOM 3705 O OD1 . ASP B 2 162 ? 91.180  110.976 74.005  1.00 174.16 ? 162 ASP B OD1 1 
ATOM 3706 O OD2 . ASP B 2 162 ? 89.105  111.638 73.709  1.00 174.16 ? 162 ASP B OD2 1 
ATOM 3707 N N   . SER B 2 163 ? 92.097  110.942 78.839  1.00 164.51 ? 163 SER B N   1 
ATOM 3708 C CA  . SER B 2 163 ? 92.420  111.387 80.189  1.00 164.51 ? 163 SER B CA  1 
ATOM 3709 C C   . SER B 2 163 ? 93.852  111.889 80.182  1.00 164.51 ? 163 SER B C   1 
ATOM 3710 O O   . SER B 2 163 ? 94.740  111.230 79.631  1.00 164.51 ? 163 SER B O   1 
ATOM 3711 C CB  . SER B 2 163 ? 92.254  110.259 81.212  1.00 164.51 ? 163 SER B CB  1 
ATOM 3712 O OG  . SER B 2 163 ? 90.961  109.674 81.127  1.00 164.51 ? 163 SER B OG  1 
ATOM 3713 N N   . LYS B 2 164 ? 94.075  113.041 80.805  1.00 162.97 ? 164 LYS B N   1 
ATOM 3714 C CA  . LYS B 2 164 ? 95.365  113.714 80.773  1.00 162.97 ? 164 LYS B CA  1 
ATOM 3715 C C   . LYS B 2 164 ? 96.209  113.339 81.987  1.00 162.97 ? 164 LYS B C   1 
ATOM 3716 O O   . LYS B 2 164 ? 97.260  113.939 82.233  1.00 162.97 ? 164 LYS B O   1 
ATOM 3717 C CB  . LYS B 2 164 ? 95.137  115.225 80.688  1.00 162.97 ? 164 LYS B CB  1 
ATOM 3718 C CG  . LYS B 2 164 ? 94.573  115.855 81.959  1.00 162.97 ? 164 LYS B CG  1 
ATOM 3719 C CD  . LYS B 2 164 ? 94.829  117.356 82.034  1.00 162.97 ? 164 LYS B CD  1 
ATOM 3720 C CE  . LYS B 2 164 ? 94.346  118.073 80.780  1.00 162.97 ? 164 LYS B CE  1 
ATOM 3721 N NZ  . LYS B 2 164 ? 92.917  117.783 80.471  1.00 162.97 ? 164 LYS B NZ  1 
ATOM 3722 N N   . LYS B 2 165 ? 95.765  112.333 82.739  1.00 156.01 ? 165 LYS B N   1 
ATOM 3723 C CA  . LYS B 2 165 ? 96.440  111.892 83.952  1.00 156.01 ? 165 LYS B CA  1 
ATOM 3724 C C   . LYS B 2 165 ? 97.207  110.586 83.782  1.00 156.01 ? 165 LYS B C   1 
ATOM 3725 O O   . LYS B 2 165 ? 97.523  109.940 84.786  1.00 156.01 ? 165 LYS B O   1 
ATOM 3726 C CB  . LYS B 2 165 ? 95.424  111.737 85.092  1.00 156.01 ? 165 LYS B CB  1 
ATOM 3727 C CG  . LYS B 2 165 ? 94.651  113.000 85.427  1.00 156.01 ? 165 LYS B CG  1 
ATOM 3728 C CD  . LYS B 2 165 ? 93.647  112.749 86.543  1.00 156.01 ? 165 LYS B CD  1 
ATOM 3729 C CE  . LYS B 2 165 ? 92.572  111.768 86.103  1.00 156.01 ? 165 LYS B CE  1 
ATOM 3730 N NZ  . LYS B 2 165 ? 91.805  112.293 84.941  1.00 156.01 ? 165 LYS B NZ  1 
ATOM 3731 N N   . TRP B 2 166 ? 97.497  110.162 82.549  1.00 144.78 ? 166 TRP B N   1 
ATOM 3732 C CA  . TRP B 2 166 ? 98.234  108.914 82.370  1.00 144.78 ? 166 TRP B CA  1 
ATOM 3733 C C   . TRP B 2 166 ? 99.722  109.082 82.642  1.00 144.78 ? 166 TRP B C   1 
ATOM 3734 O O   . TRP B 2 166 ? 100.379 108.140 83.097  1.00 144.78 ? 166 TRP B O   1 
ATOM 3735 C CB  . TRP B 2 166 ? 98.004  108.354 80.966  1.00 144.78 ? 166 TRP B CB  1 
ATOM 3736 C CG  . TRP B 2 166 ? 96.880  107.373 80.929  1.00 144.78 ? 166 TRP B CG  1 
ATOM 3737 C CD1 . TRP B 2 166 ? 95.749  107.400 81.690  1.00 144.78 ? 166 TRP B CD1 1 
ATOM 3738 C CD2 . TRP B 2 166 ? 96.783  106.202 80.108  1.00 144.78 ? 166 TRP B CD2 1 
ATOM 3739 N NE1 . TRP B 2 166 ? 94.948  106.327 81.387  1.00 144.78 ? 166 TRP B NE1 1 
ATOM 3740 C CE2 . TRP B 2 166 ? 95.559  105.575 80.419  1.00 144.78 ? 166 TRP B CE2 1 
ATOM 3741 C CE3 . TRP B 2 166 ? 97.608  105.627 79.135  1.00 144.78 ? 166 TRP B CE3 1 
ATOM 3742 C CZ2 . TRP B 2 166 ? 95.140  104.402 79.793  1.00 144.78 ? 166 TRP B CZ2 1 
ATOM 3743 C CZ3 . TRP B 2 166 ? 97.191  104.461 78.514  1.00 144.78 ? 166 TRP B CZ3 1 
ATOM 3744 C CH2 . TRP B 2 166 ? 95.967  103.862 78.846  1.00 144.78 ? 166 TRP B CH2 1 
ATOM 3745 N N   . GLY B 2 167 ? 100.271 110.265 82.380  1.00 142.82 ? 167 GLY B N   1 
ATOM 3746 C CA  . GLY B 2 167 ? 101.653 110.544 82.707  1.00 142.82 ? 167 GLY B CA  1 
ATOM 3747 C C   . GLY B 2 167 ? 101.891 111.018 84.121  1.00 142.82 ? 167 GLY B C   1 
ATOM 3748 O O   . GLY B 2 167 ? 103.039 111.307 84.476  1.00 142.82 ? 167 GLY B O   1 
ATOM 3749 N N   . MET B 2 168 ? 100.827 111.074 84.934  1.00 139.94 ? 168 MET B N   1 
ATOM 3750 C CA  . MET B 2 168 ? 100.874 111.647 86.279  1.00 139.94 ? 168 MET B CA  1 
ATOM 3751 C C   . MET B 2 168 ? 101.779 110.854 87.213  1.00 139.94 ? 168 MET B C   1 
ATOM 3752 O O   . MET B 2 168 ? 102.509 111.449 88.020  1.00 139.94 ? 168 MET B O   1 
ATOM 3753 C CB  . MET B 2 168 ? 99.446  111.728 86.834  1.00 139.94 ? 168 MET B CB  1 
ATOM 3754 C CG  . MET B 2 168 ? 99.319  112.106 88.298  1.00 139.94 ? 168 MET B CG  1 
ATOM 3755 S SD  . MET B 2 168 ? 97.607  112.309 88.827  1.00 139.94 ? 168 MET B SD  1 
ATOM 3756 C CE  . MET B 2 168 ? 96.933  110.700 88.427  1.00 139.94 ? 168 MET B CE  1 
ATOM 3757 N N   . LEU B 2 169 ? 101.793 109.520 87.070  1.00 132.14 ? 169 LEU B N   1 
ATOM 3758 C CA  . LEU B 2 169 ? 102.702 108.678 87.847  1.00 132.14 ? 169 LEU B CA  1 
ATOM 3759 C C   . LEU B 2 169 ? 104.155 108.951 87.470  1.00 132.14 ? 169 LEU B C   1 
ATOM 3760 O O   . LEU B 2 169 ? 105.052 108.853 88.316  1.00 132.14 ? 169 LEU B O   1 
ATOM 3761 C CB  . LEU B 2 169 ? 102.364 107.194 87.643  1.00 132.14 ? 169 LEU B CB  1 
ATOM 3762 C CG  . LEU B 2 169 ? 103.192 106.180 88.456  1.00 132.14 ? 169 LEU B CG  1 
ATOM 3763 C CD1 . LEU B 2 169 ? 102.973 106.373 89.950  1.00 132.14 ? 169 LEU B CD1 1 
ATOM 3764 C CD2 . LEU B 2 169 ? 102.986 104.736 88.061  1.00 132.14 ? 169 LEU B CD2 1 
ATOM 3765 N N   . PHE B 2 170 ? 104.397 109.345 86.213  1.00 134.52 ? 170 PHE B N   1 
ATOM 3766 C CA  . PHE B 2 170 ? 105.712 109.795 85.771  1.00 134.52 ? 170 PHE B CA  1 
ATOM 3767 C C   . PHE B 2 170 ? 106.075 111.075 86.515  1.00 134.52 ? 170 PHE B C   1 
ATOM 3768 O O   . PHE B 2 170 ? 107.224 111.260 86.931  1.00 134.52 ? 170 PHE B O   1 
ATOM 3769 C CB  . PHE B 2 170 ? 105.722 110.076 84.269  1.00 134.52 ? 170 PHE B CB  1 
ATOM 3770 C CG  . PHE B 2 170 ? 106.950 110.806 83.802  1.00 134.52 ? 170 PHE B CG  1 
ATOM 3771 C CD1 . PHE B 2 170 ? 108.220 110.277 84.022  1.00 134.52 ? 170 PHE B CD1 1 
ATOM 3772 C CD2 . PHE B 2 170 ? 106.842 112.079 83.266  1.00 134.52 ? 170 PHE B CD2 1 
ATOM 3773 C CE1 . PHE B 2 170 ? 109.347 110.963 83.617  1.00 134.52 ? 170 PHE B CE1 1 
ATOM 3774 C CE2 . PHE B 2 170 ? 107.968 112.776 82.876  1.00 134.52 ? 170 PHE B CE2 1 
ATOM 3775 C CZ  . PHE B 2 170 ? 109.220 112.217 83.053  1.00 134.52 ? 170 PHE B CZ  1 
ATOM 3776 N N   . LEU B 2 171 ? 105.093 111.957 86.687  1.00 130.50 ? 171 LEU B N   1 
ATOM 3777 C CA  . LEU B 2 171 ? 105.300 113.213 87.388  1.00 130.50 ? 171 LEU B CA  1 
ATOM 3778 C C   . LEU B 2 171 ? 105.529 113.047 88.879  1.00 130.50 ? 171 LEU B C   1 
ATOM 3779 O O   . LEU B 2 171 ? 106.364 113.759 89.436  1.00 130.50 ? 171 LEU B O   1 
ATOM 3780 C CB  . LEU B 2 171 ? 104.111 114.167 87.173  1.00 130.50 ? 171 LEU B CB  1 
ATOM 3781 C CG  . LEU B 2 171 ? 104.131 115.147 85.991  1.00 130.50 ? 171 LEU B CG  1 
ATOM 3782 C CD1 . LEU B 2 171 ? 105.281 116.128 86.147  1.00 130.50 ? 171 LEU B CD1 1 
ATOM 3783 C CD2 . LEU B 2 171 ? 104.182 114.467 84.629  1.00 130.50 ? 171 LEU B CD2 1 
ATOM 3784 N N   . VAL B 2 172 ? 104.840 112.107 89.533  1.00 121.48 ? 172 VAL B N   1 
ATOM 3785 C CA  . VAL B 2 172 ? 104.925 112.005 90.988  1.00 121.48 ? 172 VAL B CA  1 
ATOM 3786 C C   . VAL B 2 172 ? 106.227 111.317 91.399  1.00 121.48 ? 172 VAL B C   1 
ATOM 3787 O O   . VAL B 2 172 ? 106.706 111.483 92.526  1.00 121.48 ? 172 VAL B O   1 
ATOM 3788 C CB  . VAL B 2 172 ? 103.677 111.290 91.549  1.00 121.48 ? 172 VAL B CB  1 
ATOM 3789 C CG1 . VAL B 2 172 ? 103.713 109.798 91.292  1.00 121.48 ? 172 VAL B CG1 1 
ATOM 3790 C CG2 . VAL B 2 172 ? 103.460 111.597 93.024  1.00 121.48 ? 172 VAL B CG2 1 
ATOM 3791 N N   . ASN B 2 173 ? 106.850 110.578 90.470  1.00 122.82 ? 173 ASN B N   1 
ATOM 3792 C CA  . ASN B 2 173 ? 108.136 109.950 90.762  1.00 122.82 ? 173 ASN B CA  1 
ATOM 3793 C C   . ASN B 2 173 ? 109.253 110.974 90.785  1.00 122.82 ? 173 ASN B C   1 
ATOM 3794 O O   . ASN B 2 173 ? 110.289 110.764 91.425  1.00 122.82 ? 173 ASN B O   1 
ATOM 3795 C CB  . ASN B 2 173 ? 108.454 108.869 89.734  1.00 122.82 ? 173 ASN B CB  1 
ATOM 3796 C CG  . ASN B 2 173 ? 107.512 107.712 89.814  1.00 122.82 ? 173 ASN B CG  1 
ATOM 3797 O OD1 . ASN B 2 173 ? 107.327 107.138 90.873  1.00 122.82 ? 173 ASN B OD1 1 
ATOM 3798 N ND2 . ASN B 2 173 ? 106.901 107.362 88.695  1.00 122.82 ? 173 ASN B ND2 1 
ATOM 3799 N N   . GLN B 2 174 ? 109.065 112.085 90.077  1.00 122.59 ? 174 GLN B N   1 
ATOM 3800 C CA  . GLN B 2 174 ? 110.035 113.161 90.160  1.00 122.59 ? 174 GLN B CA  1 
ATOM 3801 C C   . GLN B 2 174 ? 109.923 113.898 91.485  1.00 122.59 ? 174 GLN B C   1 
ATOM 3802 O O   . GLN B 2 174 ? 110.947 114.195 92.103  1.00 122.59 ? 174 GLN B O   1 
ATOM 3803 C CB  . GLN B 2 174 ? 109.861 114.107 88.973  1.00 122.59 ? 174 GLN B CB  1 
ATOM 3804 C CG  . GLN B 2 174 ? 109.823 113.392 87.619  1.00 122.59 ? 174 GLN B CG  1 
ATOM 3805 C CD  . GLN B 2 174 ? 111.169 112.826 87.175  1.00 122.59 ? 174 GLN B CD  1 
ATOM 3806 O OE1 . GLN B 2 174 ? 112.218 113.162 87.717  1.00 122.59 ? 174 GLN B OE1 1 
ATOM 3807 N NE2 . GLN B 2 174 ? 111.133 111.947 86.186  1.00 122.59 ? 174 GLN B NE2 1 
ATOM 3808 N N   . LEU B 2 175 ? 108.695 114.112 91.981  1.00 123.55 ? 175 LEU B N   1 
ATOM 3809 C CA  . LEU B 2 175 ? 108.489 114.907 93.196  1.00 123.55 ? 175 LEU B CA  1 
ATOM 3810 C C   . LEU B 2 175 ? 109.002 114.213 94.456  1.00 123.55 ? 175 LEU B C   1 
ATOM 3811 O O   . LEU B 2 175 ? 109.160 114.862 95.494  1.00 123.55 ? 175 LEU B O   1 
ATOM 3812 C CB  . LEU B 2 175 ? 107.013 115.276 93.373  1.00 123.55 ? 175 LEU B CB  1 
ATOM 3813 C CG  . LEU B 2 175 ? 106.404 116.528 92.724  1.00 123.55 ? 175 LEU B CG  1 
ATOM 3814 C CD1 . LEU B 2 175 ? 107.058 117.780 93.303  1.00 123.55 ? 175 LEU B CD1 1 
ATOM 3815 C CD2 . LEU B 2 175 ? 106.468 116.552 91.211  1.00 123.55 ? 175 LEU B CD2 1 
ATOM 3816 N N   . PHE B 2 176 ? 109.244 112.901 94.408  1.00 110.56 ? 176 PHE B N   1 
ATOM 3817 C CA  . PHE B 2 176 ? 110.050 112.296 95.464  1.00 110.56 ? 176 PHE B CA  1 
ATOM 3818 C C   . PHE B 2 176 ? 111.536 112.578 95.262  1.00 110.56 ? 176 PHE B C   1 
ATOM 3819 O O   . PHE B 2 176 ? 112.268 112.782 96.237  1.00 110.56 ? 176 PHE B O   1 
ATOM 3820 C CB  . PHE B 2 176 ? 109.801 110.791 95.552  1.00 110.56 ? 176 PHE B CB  1 
ATOM 3821 C CG  . PHE B 2 176 ? 108.401 110.428 95.949  1.00 110.56 ? 176 PHE B CG  1 
ATOM 3822 C CD1 . PHE B 2 176 ? 107.937 110.715 97.226  1.00 110.56 ? 176 PHE B CD1 1 
ATOM 3823 C CD2 . PHE B 2 176 ? 107.566 109.759 95.069  1.00 110.56 ? 176 PHE B CD2 1 
ATOM 3824 C CE1 . PHE B 2 176 ? 106.647 110.373 97.606  1.00 110.56 ? 176 PHE B CE1 1 
ATOM 3825 C CE2 . PHE B 2 176 ? 106.276 109.414 95.439  1.00 110.56 ? 176 PHE B CE2 1 
ATOM 3826 C CZ  . PHE B 2 176 ? 105.817 109.719 96.711  1.00 110.56 ? 176 PHE B CZ  1 
ATOM 3827 N N   . LYS B 2 177 ? 112.000 112.601 94.011  1.00 112.88 ? 177 LYS B N   1 
ATOM 3828 C CA  . LYS B 2 177 ? 113.432 112.690 93.731  1.00 112.88 ? 177 LYS B CA  1 
ATOM 3829 C C   . LYS B 2 177 ? 114.016 114.079 93.982  1.00 112.88 ? 177 LYS B C   1 
ATOM 3830 O O   . LYS B 2 177 ? 115.167 114.165 94.419  1.00 112.88 ? 177 LYS B O   1 
ATOM 3831 C CB  . LYS B 2 177 ? 113.698 112.255 92.290  1.00 112.88 ? 177 LYS B CB  1 
ATOM 3832 C CG  . LYS B 2 177 ? 115.104 111.734 92.053  1.00 112.88 ? 177 LYS B CG  1 
ATOM 3833 C CD  . LYS B 2 177 ? 115.340 111.350 90.597  1.00 112.88 ? 177 LYS B CD  1 
ATOM 3834 C CE  . LYS B 2 177 ? 114.250 110.444 90.041  1.00 112.88 ? 177 LYS B CE  1 
ATOM 3835 N NZ  . LYS B 2 177 ? 114.721 109.683 88.850  1.00 112.88 ? 177 LYS B NZ  1 
ATOM 3836 N N   . ILE B 2 178 ? 113.272 115.156 93.726  1.00 120.33 ? 178 ILE B N   1 
ATOM 3837 C CA  . ILE B 2 178 ? 113.623 116.479 94.244  1.00 120.33 ? 178 ILE B CA  1 
ATOM 3838 C C   . ILE B 2 178 ? 113.563 116.521 95.771  1.00 120.33 ? 178 ILE B C   1 
ATOM 3839 O O   . ILE B 2 178 ? 114.494 117.024 96.415  1.00 120.33 ? 178 ILE B O   1 
ATOM 3840 C CB  . ILE B 2 178 ? 112.769 117.605 93.595  1.00 120.33 ? 178 ILE B CB  1 
ATOM 3841 C CG1 . ILE B 2 178 ? 113.015 117.778 92.076  1.00 120.33 ? 178 ILE B CG1 1 
ATOM 3842 C CG2 . ILE B 2 178 ? 112.831 118.913 94.348  1.00 120.33 ? 178 ILE B CG2 1 
ATOM 3843 C CD1 . ILE B 2 178 ? 112.202 116.992 91.102  1.00 120.33 ? 178 ILE B CD1 1 
ATOM 3844 N N   . TYR B 2 179 ? 112.511 115.946 96.365  1.00 116.45 ? 179 TYR B N   1 
ATOM 3845 C CA  . TYR B 2 179 ? 112.283 116.115 97.801  1.00 116.45 ? 179 TYR B CA  1 
ATOM 3846 C C   . TYR B 2 179 ? 113.256 115.316 98.665  1.00 116.45 ? 179 TYR B C   1 
ATOM 3847 O O   . TYR B 2 179 ? 113.433 115.631 99.847  1.00 116.45 ? 179 TYR B O   1 
ATOM 3848 C CB  . TYR B 2 179 ? 110.848 115.724 98.162  1.00 116.45 ? 179 TYR B CB  1 
ATOM 3849 C CG  . TYR B 2 179 ? 109.830 116.837 98.014  1.00 116.45 ? 179 TYR B CG  1 
ATOM 3850 C CD1 . TYR B 2 179 ? 108.536 116.687 98.505  1.00 116.45 ? 179 TYR B CD1 1 
ATOM 3851 C CD2 . TYR B 2 179 ? 110.161 118.039 97.394  1.00 116.45 ? 179 TYR B CD2 1 
ATOM 3852 C CE1 . TYR B 2 179 ? 107.598 117.700 98.380  1.00 116.45 ? 179 TYR B CE1 1 
ATOM 3853 C CE2 . TYR B 2 179 ? 109.232 119.057 97.265  1.00 116.45 ? 179 TYR B CE2 1 
ATOM 3854 C CZ  . TYR B 2 179 ? 107.954 118.882 97.758  1.00 116.45 ? 179 TYR B CZ  1 
ATOM 3855 O OH  . TYR B 2 179 ? 107.033 119.895 97.627  1.00 116.45 ? 179 TYR B OH  1 
ATOM 3856 N N   . PHE B 2 180 ? 113.894 114.286 98.107  1.00 110.72 ? 180 PHE B N   1 
ATOM 3857 C CA  . PHE B 2 180 ? 114.786 113.464 98.922  1.00 110.72 ? 180 PHE B CA  1 
ATOM 3858 C C   . PHE B 2 180 ? 116.175 114.083 99.043  1.00 110.72 ? 180 PHE B C   1 
ATOM 3859 O O   . PHE B 2 180 ? 116.822 113.962 100.089 1.00 110.72 ? 180 PHE B O   1 
ATOM 3860 C CB  . PHE B 2 180 ? 114.869 112.050 98.350  1.00 110.72 ? 180 PHE B CB  1 
ATOM 3861 C CG  . PHE B 2 180 ? 113.959 111.069 99.034  1.00 110.72 ? 180 PHE B CG  1 
ATOM 3862 C CD1 . PHE B 2 180 ? 112.585 111.265 99.041  1.00 110.72 ? 180 PHE B CD1 1 
ATOM 3863 C CD2 . PHE B 2 180 ? 114.478 109.951 99.672  1.00 110.72 ? 180 PHE B CD2 1 
ATOM 3864 C CE1 . PHE B 2 180 ? 111.740 110.364 99.666  1.00 110.72 ? 180 PHE B CE1 1 
ATOM 3865 C CE2 . PHE B 2 180 ? 113.640 109.045 100.304 1.00 110.72 ? 180 PHE B CE2 1 
ATOM 3866 C CZ  . PHE B 2 180 ? 112.268 109.255 100.300 1.00 110.72 ? 180 PHE B CZ  1 
ATOM 3867 N N   . LYS B 2 181 ? 116.655 114.744 97.986  1.00 117.61 ? 181 LYS B N   1 
ATOM 3868 C CA  . LYS B 2 181 ? 118.008 115.296 98.025  1.00 117.61 ? 181 LYS B CA  1 
ATOM 3869 C C   . LYS B 2 181 ? 118.065 116.599 98.815  1.00 117.61 ? 181 LYS B C   1 
ATOM 3870 O O   . LYS B 2 181 ? 119.113 116.947 99.373  1.00 117.61 ? 181 LYS B O   1 
ATOM 3871 C CB  . LYS B 2 181 ? 118.546 115.506 96.609  1.00 117.61 ? 181 LYS B CB  1 
ATOM 3872 C CG  . LYS B 2 181 ? 118.718 114.225 95.805  1.00 117.61 ? 181 LYS B CG  1 
ATOM 3873 C CD  . LYS B 2 181 ? 119.325 114.508 94.437  1.00 117.61 ? 181 LYS B CD  1 
ATOM 3874 C CE  . LYS B 2 181 ? 118.354 115.229 93.519  1.00 117.61 ? 181 LYS B CE  1 
ATOM 3875 N NZ  . LYS B 2 181 ? 117.186 114.384 93.165  1.00 117.61 ? 181 LYS B NZ  1 
ATOM 3876 N N   . ILE B 2 182 ? 116.954 117.339 98.867  1.00 123.98 ? 182 ILE B N   1 
ATOM 3877 C CA  . ILE B 2 182 ? 116.942 118.628 99.557  1.00 123.98 ? 182 ILE B CA  1 
ATOM 3878 C C   . ILE B 2 182 ? 116.916 118.422 101.073 1.00 123.98 ? 182 ILE B C   1 
ATOM 3879 O O   . ILE B 2 182 ? 117.398 119.271 101.838 1.00 123.98 ? 182 ILE B O   1 
ATOM 3880 C CB  . ILE B 2 182 ? 115.758 119.484 99.043  1.00 123.98 ? 182 ILE B CB  1 
ATOM 3881 C CG1 . ILE B 2 182 ? 115.786 120.921 99.583  1.00 123.98 ? 182 ILE B CG1 1 
ATOM 3882 C CG2 . ILE B 2 182 ? 114.412 118.825 99.337  1.00 123.98 ? 182 ILE B CG2 1 
ATOM 3883 C CD1 . ILE B 2 182 ? 114.690 121.804 99.033  1.00 123.98 ? 182 ILE B CD1 1 
ATOM 3884 N N   . ASN B 2 183 ? 116.430 117.250 101.516 1.00 118.50 ? 183 ASN B N   1 
ATOM 3885 C CA  . ASN B 2 183 ? 116.122 116.885 102.902 1.00 118.50 ? 183 ASN B CA  1 
ATOM 3886 C C   . ASN B 2 183 ? 115.197 117.911 103.550 1.00 118.50 ? 183 ASN B C   1 
ATOM 3887 O O   . ASN B 2 183 ? 115.477 118.413 104.641 1.00 118.50 ? 183 ASN B O   1 
ATOM 3888 C CB  . ASN B 2 183 ? 117.395 116.669 103.742 1.00 118.50 ? 183 ASN B CB  1 
ATOM 3889 C CG  . ASN B 2 183 ? 117.176 115.749 104.944 1.00 118.50 ? 183 ASN B CG  1 
ATOM 3890 O OD1 . ASN B 2 183 ? 117.607 114.597 104.969 1.00 118.50 ? 183 ASN B OD1 1 
ATOM 3891 N ND2 . ASN B 2 183 ? 116.483 116.269 105.949 1.00 118.50 ? 183 ASN B ND2 1 
ATOM 3892 N N   . LYS B 2 184 ? 114.126 118.300 102.857 1.00 119.62 ? 184 LYS B N   1 
ATOM 3893 C CA  . LYS B 2 184 ? 113.069 119.120 103.434 1.00 119.62 ? 184 LYS B CA  1 
ATOM 3894 C C   . LYS B 2 184 ? 111.705 118.453 103.183 1.00 119.62 ? 184 LYS B C   1 
ATOM 3895 O O   . LYS B 2 184 ? 110.777 119.037 102.609 1.00 119.62 ? 184 LYS B O   1 
ATOM 3896 C CB  . LYS B 2 184 ? 113.192 120.559 102.894 1.00 119.62 ? 184 LYS B CB  1 
ATOM 3897 C CG  . LYS B 2 184 ? 112.270 121.683 103.455 1.00 119.62 ? 184 LYS B CG  1 
ATOM 3898 C CD  . LYS B 2 184 ? 112.138 121.592 104.971 1.00 119.62 ? 184 LYS B CD  1 
ATOM 3899 C CE  . LYS B 2 184 ? 113.336 122.225 105.665 1.00 119.62 ? 184 LYS B CE  1 
ATOM 3900 N NZ  . LYS B 2 184 ? 113.530 121.703 107.046 1.00 119.62 ? 184 LYS B NZ  1 
ATOM 3901 N N   . LEU B 2 185 ? 111.619 117.161 103.499 1.00 123.20 ? 185 LEU B N   1 
ATOM 3902 C CA  . LEU B 2 185 ? 110.412 116.364 103.285 1.00 123.20 ? 185 LEU B CA  1 
ATOM 3903 C C   . LEU B 2 185 ? 109.554 116.310 104.560 1.00 123.20 ? 185 LEU B C   1 
ATOM 3904 O O   . LEU B 2 185 ? 109.176 115.260 105.081 1.00 123.20 ? 185 LEU B O   1 
ATOM 3905 C CB  . LEU B 2 185 ? 110.811 114.992 102.734 1.00 123.20 ? 185 LEU B CB  1 
ATOM 3906 C CG  . LEU B 2 185 ? 111.498 113.789 103.417 1.00 123.20 ? 185 LEU B CG  1 
ATOM 3907 C CD1 . LEU B 2 185 ? 111.339 112.545 102.568 1.00 123.20 ? 185 LEU B CD1 1 
ATOM 3908 C CD2 . LEU B 2 185 ? 112.972 114.048 103.699 1.00 123.20 ? 185 LEU B CD2 1 
ATOM 3909 N N   . HIS B 2 186 ? 109.199 117.508 105.036 1.00 132.32 ? 186 HIS B N   1 
ATOM 3910 C CA  . HIS B 2 186 ? 108.438 117.618 106.279 1.00 132.32 ? 186 HIS B CA  1 
ATOM 3911 C C   . HIS B 2 186 ? 106.982 117.190 106.094 1.00 132.32 ? 186 HIS B C   1 
ATOM 3912 O O   . HIS B 2 186 ? 106.432 116.480 106.944 1.00 132.32 ? 186 HIS B O   1 
ATOM 3913 C CB  . HIS B 2 186 ? 108.560 119.042 106.839 1.00 132.32 ? 186 HIS B CB  1 
ATOM 3914 C CG  . HIS B 2 186 ? 107.957 120.103 105.971 1.00 132.32 ? 186 HIS B CG  1 
ATOM 3915 N ND1 . HIS B 2 186 ? 108.609 120.626 104.875 1.00 132.32 ? 186 HIS B ND1 1 
ATOM 3916 C CD2 . HIS B 2 186 ? 106.768 120.746 106.042 1.00 132.32 ? 186 HIS B CD2 1 
ATOM 3917 C CE1 . HIS B 2 186 ? 107.845 121.540 104.305 1.00 132.32 ? 186 HIS B CE1 1 
ATOM 3918 N NE2 . HIS B 2 186 ? 106.721 121.631 104.993 1.00 132.32 ? 186 HIS B NE2 1 
ATOM 3919 N N   . LEU B 2 187 ? 106.352 117.577 104.985 1.00 136.51 ? 187 LEU B N   1 
ATOM 3920 C CA  . LEU B 2 187 ? 105.018 117.095 104.646 1.00 136.51 ? 187 LEU B CA  1 
ATOM 3921 C C   . LEU B 2 187 ? 105.003 116.649 103.192 1.00 136.51 ? 187 LEU B C   1 
ATOM 3922 O O   . LEU B 2 187 ? 105.089 117.481 102.284 1.00 136.51 ? 187 LEU B O   1 
ATOM 3923 C CB  . LEU B 2 187 ? 103.936 118.163 104.871 1.00 136.51 ? 187 LEU B CB  1 
ATOM 3924 C CG  . LEU B 2 187 ? 103.211 118.344 106.216 1.00 136.51 ? 187 LEU B CG  1 
ATOM 3925 C CD1 . LEU B 2 187 ? 102.456 117.069 106.584 1.00 136.51 ? 187 LEU B CD1 1 
ATOM 3926 C CD2 . LEU B 2 187 ? 104.091 118.813 107.368 1.00 136.51 ? 187 LEU B CD2 1 
ATOM 3927 N N   . CYS B 2 188 ? 104.897 115.336 102.980 1.00 136.49 ? 188 CYS B N   1 
ATOM 3928 C CA  . CYS B 2 188 ? 104.682 114.772 101.652 1.00 136.49 ? 188 CYS B CA  1 
ATOM 3929 C C   . CYS B 2 188 ? 103.335 114.066 101.570 1.00 136.49 ? 188 CYS B C   1 
ATOM 3930 O O   . CYS B 2 188 ? 103.027 113.446 100.548 1.00 136.49 ? 188 CYS B O   1 
ATOM 3931 C CB  . CYS B 2 188 ? 105.805 113.801 101.282 1.00 136.49 ? 188 CYS B CB  1 
ATOM 3932 S SG  . CYS B 2 188 ? 107.438 114.552 101.156 1.00 136.49 ? 188 CYS B SG  1 
ATOM 3933 N N   . LYS B 2 189 ? 102.534 114.155 102.629 1.00 144.37 ? 189 LYS B N   1 
ATOM 3934 C CA  . LYS B 2 189 ? 101.290 113.412 102.816 1.00 144.37 ? 189 LYS B CA  1 
ATOM 3935 C C   . LYS B 2 189 ? 100.166 113.703 101.808 1.00 144.37 ? 189 LYS B C   1 
ATOM 3936 O O   . LYS B 2 189 ? 99.591  112.731 101.302 1.00 144.37 ? 189 LYS B O   1 
ATOM 3937 C CB  . LYS B 2 189 ? 100.800 113.612 104.257 1.00 144.37 ? 189 LYS B CB  1 
ATOM 3938 C CG  . LYS B 2 189 ? 99.625  112.742 104.657 1.00 144.37 ? 189 LYS B CG  1 
ATOM 3939 C CD  . LYS B 2 189 ? 99.216  113.018 106.093 1.00 144.37 ? 189 LYS B CD  1 
ATOM 3940 C CE  . LYS B 2 189 ? 100.270 112.509 107.064 1.00 144.37 ? 189 LYS B CE  1 
ATOM 3941 N NZ  . LYS B 2 189 ? 100.374 111.024 107.051 1.00 144.37 ? 189 LYS B NZ  1 
ATOM 3942 N N   . PRO B 2 190 ? 99.783  114.995 101.451 1.00 144.54 ? 190 PRO B N   1 
ATOM 3943 C CA  . PRO B 2 190 ? 98.696  115.136 100.464 1.00 144.54 ? 190 PRO B CA  1 
ATOM 3944 C C   . PRO B 2 190 ? 99.130  114.822 99.039  1.00 144.54 ? 190 PRO B C   1 
ATOM 3945 O O   . PRO B 2 190 ? 98.293  114.593 98.161  1.00 144.54 ? 190 PRO B O   1 
ATOM 3946 C CB  . PRO B 2 190 ? 98.277  116.604 100.600 1.00 144.54 ? 190 PRO B CB  1 
ATOM 3947 C CG  . PRO B 2 190 ? 99.479  117.287 101.040 1.00 144.54 ? 190 PRO B CG  1 
ATOM 3948 C CD  . PRO B 2 190 ? 100.190 116.332 101.944 1.00 144.54 ? 190 PRO B CD  1 
ATOM 3949 N N   . LEU B 2 191 ? 100.444 114.806 98.806  1.00 140.03 ? 191 LEU B N   1 
ATOM 3950 C CA  . LEU B 2 191 ? 100.972 114.436 97.497  1.00 140.03 ? 191 LEU B CA  1 
ATOM 3951 C C   . LEU B 2 191 ? 100.889 112.928 97.275  1.00 140.03 ? 191 LEU B C   1 
ATOM 3952 O O   . LEU B 2 191 ? 100.915 112.456 96.133  1.00 140.03 ? 191 LEU B O   1 
ATOM 3953 C CB  . LEU B 2 191 ? 102.410 114.960 97.373  1.00 140.03 ? 191 LEU B CB  1 
ATOM 3954 C CG  . LEU B 2 191 ? 103.289 114.881 96.119  1.00 140.03 ? 191 LEU B CG  1 
ATOM 3955 C CD1 . LEU B 2 191 ? 104.225 116.073 96.105  1.00 140.03 ? 191 LEU B CD1 1 
ATOM 3956 C CD2 . LEU B 2 191 ? 104.129 113.617 96.102  1.00 140.03 ? 191 LEU B CD2 1 
ATOM 3957 N N   . ILE B 2 192 ? 100.784 112.157 98.359  1.00 137.70 ? 192 ILE B N   1 
ATOM 3958 C CA  . ILE B 2 192 ? 100.762 110.700 98.251  1.00 137.70 ? 192 ILE B CA  1 
ATOM 3959 C C   . ILE B 2 192 ? 99.322  110.188 98.294  1.00 137.70 ? 192 ILE B C   1 
ATOM 3960 O O   . ILE B 2 192 ? 98.941  109.275 97.546  1.00 137.70 ? 192 ILE B O   1 
ATOM 3961 C CB  . ILE B 2 192 ? 101.641 110.087 99.360  1.00 137.70 ? 192 ILE B CB  1 
ATOM 3962 C CG1 . ILE B 2 192 ? 103.108 110.446 99.117  1.00 137.70 ? 192 ILE B CG1 1 
ATOM 3963 C CG2 . ILE B 2 192 ? 101.529 108.579 99.420  1.00 137.70 ? 192 ILE B CG2 1 
ATOM 3964 C CD1 . ILE B 2 192 ? 104.022 110.092 100.265 1.00 137.70 ? 192 ILE B CD1 1 
ATOM 3965 N N   . ARG B 2 193 ? 98.486  110.814 99.133  1.00 148.08 ? 193 ARG B N   1 
ATOM 3966 C CA  . ARG B 2 193 ? 97.098  110.382 99.301  1.00 148.08 ? 193 ARG B CA  1 
ATOM 3967 C C   . ARG B 2 193 ? 96.243  110.700 98.079  1.00 148.08 ? 193 ARG B C   1 
ATOM 3968 O O   . ARG B 2 193 ? 95.183  110.091 97.887  1.00 148.08 ? 193 ARG B O   1 
ATOM 3969 C CB  . ARG B 2 193 ? 96.487  111.038 100.539 1.00 148.08 ? 193 ARG B CB  1 
ATOM 3970 C CG  . ARG B 2 193 ? 97.090  110.615 101.873 1.00 148.08 ? 193 ARG B CG  1 
ATOM 3971 C CD  . ARG B 2 193 ? 96.520  111.216 103.216 1.00 148.08 ? 193 ARG B CD  1 
ATOM 3972 N NE  . ARG B 2 193 ? 96.340  112.665 103.375 1.00 148.08 ? 193 ARG B NE  1 
ATOM 3973 C CZ  . ARG B 2 193 ? 95.424  113.442 102.803 1.00 148.08 ? 193 ARG B CZ  1 
ATOM 3974 N NH1 . ARG B 2 193 ? 94.358  112.941 102.200 1.00 148.08 ? 193 ARG B NH1 1 
ATOM 3975 N NH2 . ARG B 2 193 ? 95.544  114.763 102.904 1.00 148.08 ? 193 ARG B NH2 1 
ATOM 3976 N N   . ALA B 2 194 ? 96.671  111.661 97.257  1.00 143.95 ? 194 ALA B N   1 
ATOM 3977 C CA  . ALA B 2 194 ? 95.911  112.016 96.062  1.00 143.95 ? 194 ALA B CA  1 
ATOM 3978 C C   . ALA B 2 194 ? 96.008  110.926 95.001  1.00 143.95 ? 194 ALA B C   1 
ATOM 3979 O O   . ALA B 2 194 ? 95.062  110.700 94.238  1.00 143.95 ? 194 ALA B O   1 
ATOM 3980 C CB  . ALA B 2 194 ? 96.402  113.354 95.509  1.00 143.95 ? 194 ALA B CB  1 
ATOM 3981 N N   . ILE B 2 195 ? 97.148  110.234 94.942  1.00 139.05 ? 195 ILE B N   1 
ATOM 3982 C CA  . ILE B 2 195 ? 97.334  109.227 93.905  1.00 139.05 ? 195 ILE B CA  1 
ATOM 3983 C C   . ILE B 2 195 ? 97.131  107.825 94.490  1.00 139.05 ? 195 ILE B C   1 
ATOM 3984 O O   . ILE B 2 195 ? 96.893  106.858 93.752  1.00 139.05 ? 195 ILE B O   1 
ATOM 3985 C CB  . ILE B 2 195 ? 98.718  109.437 93.246  1.00 139.05 ? 195 ILE B CB  1 
ATOM 3986 C CG1 . ILE B 2 195 ? 98.896  108.604 91.969  1.00 139.05 ? 195 ILE B CG1 1 
ATOM 3987 C CG2 . ILE B 2 195 ? 99.836  109.145 94.236  1.00 139.05 ? 195 ILE B CG2 1 
ATOM 3988 C CD1 . ILE B 2 195 ? 100.069 109.004 91.130  1.00 139.05 ? 195 ILE B CD1 1 
ATOM 3989 N N   . ASP B 2 196 ? 97.159  107.698 95.824  1.00 146.74 ? 196 ASP B N   1 
ATOM 3990 C CA  . ASP B 2 196 ? 96.815  106.424 96.455  1.00 146.74 ? 196 ASP B CA  1 
ATOM 3991 C C   . ASP B 2 196 ? 95.333  106.104 96.288  1.00 146.74 ? 196 ASP B C   1 
ATOM 3992 O O   . ASP B 2 196 ? 94.944  104.934 96.192  1.00 146.74 ? 196 ASP B O   1 
ATOM 3993 C CB  . ASP B 2 196 ? 97.195  106.436 97.935  1.00 146.74 ? 196 ASP B CB  1 
ATOM 3994 C CG  . ASP B 2 196 ? 98.582  105.883 98.185  1.00 146.74 ? 196 ASP B CG  1 
ATOM 3995 O OD1 . ASP B 2 196 ? 99.048  105.054 97.375  1.00 146.74 ? 196 ASP B OD1 1 
ATOM 3996 O OD2 . ASP B 2 196 ? 99.191  106.247 99.210  1.00 146.74 ? 196 ASP B OD2 1 
ATOM 3997 N N   . SER B 2 197 ? 94.490  107.132 96.253  1.00 147.89 ? 197 SER B N   1 
ATOM 3998 C CA  . SER B 2 197 ? 93.087  106.954 95.903  1.00 147.89 ? 197 SER B CA  1 
ATOM 3999 C C   . SER B 2 197 ? 92.911  107.216 94.411  1.00 147.89 ? 197 SER B C   1 
ATOM 4000 O O   . SER B 2 197 ? 92.737  108.366 93.994  1.00 147.89 ? 197 SER B O   1 
ATOM 4001 C CB  . SER B 2 197 ? 92.207  107.889 96.728  1.00 147.89 ? 197 SER B CB  1 
ATOM 4002 O OG  . SER B 2 197 ? 92.564  107.846 98.099  1.00 147.89 ? 197 SER B OG  1 
ATOM 4003 N N   . SER B 2 198 ? 92.962  106.155 93.610  1.00 150.09 ? 198 SER B N   1 
ATOM 4004 C CA  . SER B 2 198 ? 92.859  106.286 92.163  1.00 150.09 ? 198 SER B CA  1 
ATOM 4005 C C   . SER B 2 198 ? 92.261  105.009 91.593  1.00 150.09 ? 198 SER B C   1 
ATOM 4006 O O   . SER B 2 198 ? 92.492  103.911 92.106  1.00 150.09 ? 198 SER B O   1 
ATOM 4007 C CB  . SER B 2 198 ? 94.222  106.572 91.524  1.00 150.09 ? 198 SER B CB  1 
ATOM 4008 O OG  . SER B 2 198 ? 94.130  106.575 90.111  1.00 150.09 ? 198 SER B OG  1 
ATOM 4009 N N   . ASN B 2 199 ? 91.486  105.173 90.519  1.00 148.28 ? 199 ASN B N   1 
ATOM 4010 C CA  . ASN B 2 199 ? 90.850  104.034 89.865  1.00 148.28 ? 199 ASN B CA  1 
ATOM 4011 C C   . ASN B 2 199 ? 91.846  103.252 89.017  1.00 148.28 ? 199 ASN B C   1 
ATOM 4012 O O   . ASN B 2 199 ? 91.739  102.027 88.889  1.00 148.28 ? 199 ASN B O   1 
ATOM 4013 C CB  . ASN B 2 199 ? 89.677  104.512 89.008  1.00 148.28 ? 199 ASN B CB  1 
ATOM 4014 C CG  . ASN B 2 199 ? 88.400  104.675 89.807  1.00 148.28 ? 199 ASN B CG  1 
ATOM 4015 O OD1 . ASN B 2 199 ? 88.400  104.547 91.031  1.00 148.28 ? 199 ASN B OD1 1 
ATOM 4016 N ND2 . ASN B 2 199 ? 87.304  104.962 89.116  1.00 148.28 ? 199 ASN B ND2 1 
ATOM 4017 N N   . LEU B 2 200 ? 92.819  103.945 88.427  1.00 156.59 ? 200 LEU B N   1 
ATOM 4018 C CA  . LEU B 2 200 ? 93.811  103.337 87.550  1.00 156.59 ? 200 LEU B CA  1 
ATOM 4019 C C   . LEU B 2 200 ? 95.092  102.952 88.276  1.00 156.59 ? 200 LEU B C   1 
ATOM 4020 O O   . LEU B 2 200 ? 96.147  102.954 87.635  1.00 156.59 ? 200 LEU B O   1 
ATOM 4021 C CB  . LEU B 2 200 ? 94.151  104.281 86.389  1.00 156.59 ? 200 LEU B CB  1 
ATOM 4022 C CG  . LEU B 2 200 ? 93.346  104.297 85.080  1.00 156.59 ? 200 LEU B CG  1 
ATOM 4023 C CD1 . LEU B 2 200 ? 93.466  102.957 84.362  1.00 156.59 ? 200 LEU B CD1 1 
ATOM 4024 C CD2 . LEU B 2 200 ? 91.881  104.691 85.262  1.00 156.59 ? 200 LEU B CD2 1 
ATOM 4025 N N   . LYS B 2 201 ? 95.008  102.616 89.570  1.00 151.53 ? 201 LYS B N   1 
ATOM 4026 C CA  . LYS B 2 201 ? 96.199  102.432 90.400  1.00 151.53 ? 201 LYS B CA  1 
ATOM 4027 C C   . LYS B 2 201 ? 96.994  101.194 89.994  1.00 151.53 ? 201 LYS B C   1 
ATOM 4028 O O   . LYS B 2 201 ? 98.228  101.187 90.067  1.00 151.53 ? 201 LYS B O   1 
ATOM 4029 C CB  . LYS B 2 201 ? 95.790  102.348 91.873  1.00 151.53 ? 201 LYS B CB  1 
ATOM 4030 C CG  . LYS B 2 201 ? 96.943  102.402 92.864  1.00 151.53 ? 201 LYS B CG  1 
ATOM 4031 C CD  . LYS B 2 201 ? 96.439  102.531 94.293  1.00 151.53 ? 201 LYS B CD  1 
ATOM 4032 C CE  . LYS B 2 201 ? 95.867  101.216 94.799  1.00 151.53 ? 201 LYS B CE  1 
ATOM 4033 N NZ  . LYS B 2 201 ? 95.026  101.407 96.013  1.00 151.53 ? 201 LYS B NZ  1 
ATOM 4034 N N   . ASP B 2 202 ? 96.310  100.149 89.541  1.00 155.88 ? 202 ASP B N   1 
ATOM 4035 C CA  . ASP B 2 202 ? 96.965  98.906  89.161  1.00 155.88 ? 202 ASP B CA  1 
ATOM 4036 C C   . ASP B 2 202 ? 97.349  98.855  87.686  1.00 155.88 ? 202 ASP B C   1 
ATOM 4037 O O   . ASP B 2 202 ? 97.797  97.804  87.217  1.00 155.88 ? 202 ASP B O   1 
ATOM 4038 C CB  . ASP B 2 202 ? 96.072  97.712  89.506  1.00 155.88 ? 202 ASP B CB  1 
ATOM 4039 C CG  . ASP B 2 202 ? 96.016  97.438  90.997  1.00 155.88 ? 202 ASP B CG  1 
ATOM 4040 O OD1 . ASP B 2 202 ? 96.477  98.297  91.778  1.00 155.88 ? 202 ASP B OD1 1 
ATOM 4041 O OD2 . ASP B 2 202 ? 95.515  96.363  91.387  1.00 155.88 ? 202 ASP B OD2 1 
ATOM 4042 N N   . ASP B 2 203 ? 97.188  99.951  86.944  1.00 155.32 ? 203 ASP B N   1 
ATOM 4043 C CA  . ASP B 2 203 ? 97.519  99.972  85.521  1.00 155.32 ? 203 ASP B CA  1 
ATOM 4044 C C   . ASP B 2 203 ? 98.186  101.298 85.172  1.00 155.32 ? 203 ASP B C   1 
ATOM 4045 O O   . ASP B 2 203 ? 97.523  102.339 85.108  1.00 155.32 ? 203 ASP B O   1 
ATOM 4046 C CB  . ASP B 2 203 ? 96.273  99.739  84.661  1.00 155.32 ? 203 ASP B CB  1 
ATOM 4047 C CG  . ASP B 2 203 ? 96.492  100.100 83.202  1.00 155.32 ? 203 ASP B CG  1 
ATOM 4048 O OD1 . ASP B 2 203 ? 97.232  99.367  82.512  1.00 155.32 ? 203 ASP B OD1 1 
ATOM 4049 O OD2 . ASP B 2 203 ? 95.929  101.118 82.749  1.00 155.32 ? 203 ASP B OD2 1 
ATOM 4050 N N   . TYR B 2 204 ? 99.498  101.255 84.978  1.00 142.87 ? 204 TYR B N   1 
ATOM 4051 C CA  . TYR B 2 204 ? 100.272 102.326 84.359  1.00 142.87 ? 204 TYR B CA  1 
ATOM 4052 C C   . TYR B 2 204 ? 101.385 101.675 83.547  1.00 142.87 ? 204 TYR B C   1 
ATOM 4053 O O   . TYR B 2 204 ? 101.349 100.470 83.276  1.00 142.87 ? 204 TYR B O   1 
ATOM 4054 C CB  . TYR B 2 204 ? 100.846 103.302 85.401  1.00 142.87 ? 204 TYR B CB  1 
ATOM 4055 C CG  . TYR B 2 204 ? 99.870  104.215 86.109  1.00 142.87 ? 204 TYR B CG  1 
ATOM 4056 C CD1 . TYR B 2 204 ? 99.369  105.350 85.476  1.00 142.87 ? 204 TYR B CD1 1 
ATOM 4057 C CD2 . TYR B 2 204 ? 99.504  103.985 87.432  1.00 142.87 ? 204 TYR B CD2 1 
ATOM 4058 C CE1 . TYR B 2 204 ? 98.496  106.208 86.127  1.00 142.87 ? 204 TYR B CE1 1 
ATOM 4059 C CE2 . TYR B 2 204 ? 98.644  104.845 88.097  1.00 142.87 ? 204 TYR B CE2 1 
ATOM 4060 C CZ  . TYR B 2 204 ? 98.137  105.947 87.436  1.00 142.87 ? 204 TYR B CZ  1 
ATOM 4061 O OH  . TYR B 2 204 ? 97.272  106.795 88.089  1.00 142.87 ? 204 TYR B OH  1 
ATOM 4062 N N   . SER B 2 205 ? 102.373 102.473 83.151  1.00 132.78 ? 205 SER B N   1 
ATOM 4063 C CA  . SER B 2 205 ? 103.631 101.917 82.676  1.00 132.78 ? 205 SER B CA  1 
ATOM 4064 C C   . SER B 2 205 ? 104.369 101.271 83.841  1.00 132.78 ? 205 SER B C   1 
ATOM 4065 O O   . SER B 2 205 ? 104.477 101.851 84.925  1.00 132.78 ? 205 SER B O   1 
ATOM 4066 C CB  . SER B 2 205 ? 104.492 103.007 82.040  1.00 132.78 ? 205 SER B CB  1 
ATOM 4067 O OG  . SER B 2 205 ? 105.065 103.844 83.030  1.00 132.78 ? 205 SER B OG  1 
ATOM 4068 N N   . THR B 2 206 ? 104.881 100.057 83.617  1.00 125.15 ? 206 THR B N   1 
ATOM 4069 C CA  . THR B 2 206 ? 105.434 99.288  84.728  1.00 125.15 ? 206 THR B CA  1 
ATOM 4070 C C   . THR B 2 206 ? 106.846 99.732  85.088  1.00 125.15 ? 206 THR B C   1 
ATOM 4071 O O   . THR B 2 206 ? 107.365 99.336  86.137  1.00 125.15 ? 206 THR B O   1 
ATOM 4072 C CB  . THR B 2 206 ? 105.412 97.791  84.407  1.00 125.15 ? 206 THR B CB  1 
ATOM 4073 O OG1 . THR B 2 206 ? 105.813 97.050  85.566  1.00 125.15 ? 206 THR B OG1 1 
ATOM 4074 C CG2 . THR B 2 206 ? 106.350 97.467  83.262  1.00 125.15 ? 206 THR B CG2 1 
ATOM 4075 N N   . ALA B 2 207 ? 107.484 100.542 84.240  1.00 126.08 ? 207 ALA B N   1 
ATOM 4076 C CA  . ALA B 2 207 ? 108.771 101.122 84.605  1.00 126.08 ? 207 ALA B CA  1 
ATOM 4077 C C   . ALA B 2 207 ? 108.605 102.178 85.689  1.00 126.08 ? 207 ALA B C   1 
ATOM 4078 O O   . ALA B 2 207 ? 109.446 102.295 86.589  1.00 126.08 ? 207 ALA B O   1 
ATOM 4079 C CB  . ALA B 2 207 ? 109.450 101.719 83.374  1.00 126.08 ? 207 ALA B CB  1 
ATOM 4080 N N   . GLN B 2 208 ? 107.523 102.955 85.619  1.00 119.48 ? 208 GLN B N   1 
ATOM 4081 C CA  . GLN B 2 208 ? 107.267 103.967 86.636  1.00 119.48 ? 208 GLN B CA  1 
ATOM 4082 C C   . GLN B 2 208 ? 106.566 103.374 87.851  1.00 119.48 ? 208 GLN B C   1 
ATOM 4083 O O   . GLN B 2 208 ? 106.517 104.009 88.910  1.00 119.48 ? 208 GLN B O   1 
ATOM 4084 C CB  . GLN B 2 208 ? 106.439 105.102 86.034  1.00 119.48 ? 208 GLN B CB  1 
ATOM 4085 C CG  . GLN B 2 208 ? 107.264 106.274 85.516  1.00 119.48 ? 208 GLN B CG  1 
ATOM 4086 C CD  . GLN B 2 208 ? 108.186 105.889 84.377  1.00 119.48 ? 208 GLN B CD  1 
ATOM 4087 O OE1 . GLN B 2 208 ? 107.739 105.414 83.334  1.00 119.48 ? 208 GLN B OE1 1 
ATOM 4088 N NE2 . GLN B 2 208 ? 109.483 106.100 84.569  1.00 119.48 ? 208 GLN B NE2 1 
ATOM 4089 N N   . ARG B 2 209 ? 106.015 102.163 87.720  1.00 119.26 ? 209 ARG B N   1 
ATOM 4090 C CA  . ARG B 2 209 ? 105.311 101.546 88.840  1.00 119.26 ? 209 ARG B CA  1 
ATOM 4091 C C   . ARG B 2 209 ? 106.290 101.000 89.875  1.00 119.26 ? 209 ARG B C   1 
ATOM 4092 O O   . ARG B 2 209 ? 105.967 100.925 91.067  1.00 119.26 ? 209 ARG B O   1 
ATOM 4093 C CB  . ARG B 2 209 ? 104.381 100.440 88.332  1.00 119.26 ? 209 ARG B CB  1 
ATOM 4094 C CG  . ARG B 2 209 ? 103.148 100.241 89.203  1.00 119.26 ? 209 ARG B CG  1 
ATOM 4095 C CD  . ARG B 2 209 ? 101.987 99.572  88.483  1.00 119.26 ? 209 ARG B CD  1 
ATOM 4096 N NE  . ARG B 2 209 ? 102.216 98.148  88.272  1.00 119.26 ? 209 ARG B NE  1 
ATOM 4097 C CZ  . ARG B 2 209 ? 102.419 97.591  87.086  1.00 119.26 ? 209 ARG B CZ  1 
ATOM 4098 N NH1 . ARG B 2 209 ? 102.374 98.302  85.973  1.00 119.26 ? 209 ARG B NH1 1 
ATOM 4099 N NH2 . ARG B 2 209 ? 102.659 96.285  87.015  1.00 119.26 ? 209 ARG B NH2 1 
ATOM 4100 N N   . VAL B 2 210 ? 107.485 100.599 89.434  1.00 114.87 ? 210 VAL B N   1 
ATOM 4101 C CA  . VAL B 2 210 ? 108.519 100.133 90.355  1.00 114.87 ? 210 VAL B CA  1 
ATOM 4102 C C   . VAL B 2 210 ? 109.105 101.306 91.139  1.00 114.87 ? 210 VAL B C   1 
ATOM 4103 O O   . VAL B 2 210 ? 109.411 101.189 92.334  1.00 114.87 ? 210 VAL B O   1 
ATOM 4104 C CB  . VAL B 2 210 ? 109.597 99.357  89.567  1.00 114.87 ? 210 VAL B CB  1 
ATOM 4105 C CG1 . VAL B 2 210 ? 110.723 98.857  90.467  1.00 114.87 ? 210 VAL B CG1 1 
ATOM 4106 C CG2 . VAL B 2 210 ? 108.968 98.188  88.833  1.00 114.87 ? 210 VAL B CG2 1 
ATOM 4107 N N   . THR B 2 211 ? 109.185 102.475 90.509  1.00 113.09 ? 211 THR B N   1 
ATOM 4108 C CA  . THR B 2 211 ? 109.974 103.612 90.990  1.00 113.09 ? 211 THR B CA  1 
ATOM 4109 C C   . THR B 2 211 ? 109.166 104.446 92.005  1.00 113.09 ? 211 THR B C   1 
ATOM 4110 O O   . THR B 2 211 ? 109.655 105.353 92.682  1.00 113.09 ? 211 THR B O   1 
ATOM 4111 C CB  . THR B 2 211 ? 110.411 104.419 89.761  1.00 113.09 ? 211 THR B CB  1 
ATOM 4112 O OG1 . THR B 2 211 ? 111.052 103.524 88.846  1.00 113.09 ? 211 THR B OG1 1 
ATOM 4113 C CG2 . THR B 2 211 ? 111.474 105.486 90.064  1.00 113.09 ? 211 THR B CG2 1 
ATOM 4114 N N   . TYR B 2 212 ? 107.918 104.038 92.230  1.00 116.88 ? 212 TYR B N   1 
ATOM 4115 C CA  . TYR B 2 212 ? 107.019 104.774 93.111  1.00 116.88 ? 212 TYR B CA  1 
ATOM 4116 C C   . TYR B 2 212 ? 107.028 104.197 94.516  1.00 116.88 ? 212 TYR B C   1 
ATOM 4117 O O   . TYR B 2 212 ? 107.344 104.896 95.489  1.00 116.88 ? 212 TYR B O   1 
ATOM 4118 C CB  . TYR B 2 212 ? 105.597 104.743 92.541  1.00 116.88 ? 212 TYR B CB  1 
ATOM 4119 C CG  . TYR B 2 212 ? 104.526 105.316 93.447  1.00 116.88 ? 212 TYR B CG  1 
ATOM 4120 C CD1 . TYR B 2 212 ? 104.652 106.584 94.012  1.00 116.88 ? 212 TYR B CD1 1 
ATOM 4121 C CD2 . TYR B 2 212 ? 103.395 104.566 93.759  1.00 116.88 ? 212 TYR B CD2 1 
ATOM 4122 C CE1 . TYR B 2 212 ? 103.668 107.093 94.848  1.00 116.88 ? 212 TYR B CE1 1 
ATOM 4123 C CE2 . TYR B 2 212 ? 102.411 105.064 94.592  1.00 116.88 ? 212 TYR B CE2 1 
ATOM 4124 C CZ  . TYR B 2 212 ? 102.554 106.327 95.133  1.00 116.88 ? 212 TYR B CZ  1 
ATOM 4125 O OH  . TYR B 2 212 ? 101.575 106.822 95.962  1.00 116.88 ? 212 TYR B OH  1 
ATOM 4126 N N   . LYS B 2 213 ? 106.719 102.911 94.631  1.00 114.15 ? 213 LYS B N   1 
ATOM 4127 C CA  . LYS B 2 213 ? 106.660 102.332 95.960  1.00 114.15 ? 213 LYS B CA  1 
ATOM 4128 C C   . LYS B 2 213 ? 108.024 101.965 96.512  1.00 114.15 ? 213 LYS B C   1 
ATOM 4129 O O   . LYS B 2 213 ? 108.100 101.629 97.692  1.00 114.15 ? 213 LYS B O   1 
ATOM 4130 C CB  . LYS B 2 213 ? 105.712 101.141 95.961  1.00 114.15 ? 213 LYS B CB  1 
ATOM 4131 C CG  . LYS B 2 213 ? 105.768 100.314 94.721  1.00 114.15 ? 213 LYS B CG  1 
ATOM 4132 C CD  . LYS B 2 213 ? 104.583 99.389  94.696  1.00 114.15 ? 213 LYS B CD  1 
ATOM 4133 C CE  . LYS B 2 213 ? 104.439 98.810  93.329  1.00 114.15 ? 213 LYS B CE  1 
ATOM 4134 N NZ  . LYS B 2 213 ? 104.060 99.901  92.409  1.00 114.15 ? 213 LYS B NZ  1 
ATOM 4135 N N   . TYR B 2 214 ? 109.092 102.096 95.722  1.00 102.69 ? 214 TYR B N   1 
ATOM 4136 C CA  . TYR B 2 214 ? 110.431 102.216 96.288  1.00 102.69 ? 214 TYR B CA  1 
ATOM 4137 C C   . TYR B 2 214 ? 110.546 103.440 97.196  1.00 102.69 ? 214 TYR B C   1 
ATOM 4138 O O   . TYR B 2 214 ? 110.972 103.319 98.351  1.00 102.69 ? 214 TYR B O   1 
ATOM 4139 C CB  . TYR B 2 214 ? 111.449 102.285 95.148  1.00 102.69 ? 214 TYR B CB  1 
ATOM 4140 C CG  . TYR B 2 214 ? 112.892 102.374 95.577  1.00 102.69 ? 214 TYR B CG  1 
ATOM 4141 C CD1 . TYR B 2 214 ? 113.564 101.257 96.055  1.00 102.69 ? 214 TYR B CD1 1 
ATOM 4142 C CD2 . TYR B 2 214 ? 113.589 103.574 95.481  1.00 102.69 ? 214 TYR B CD2 1 
ATOM 4143 C CE1 . TYR B 2 214 ? 114.889 101.333 96.444  1.00 102.69 ? 214 TYR B CE1 1 
ATOM 4144 C CE2 . TYR B 2 214 ? 114.914 103.663 95.865  1.00 102.69 ? 214 TYR B CE2 1 
ATOM 4145 C CZ  . TYR B 2 214 ? 115.555 102.539 96.345  1.00 102.69 ? 214 TYR B CZ  1 
ATOM 4146 O OH  . TYR B 2 214 ? 116.869 102.618 96.728  1.00 102.69 ? 214 TYR B OH  1 
ATOM 4147 N N   . TYR B 2 215 ? 110.100 104.609 96.723  1.00 106.40 ? 215 TYR B N   1 
ATOM 4148 C CA  . TYR B 2 215 ? 110.176 105.820 97.537  1.00 106.40 ? 215 TYR B CA  1 
ATOM 4149 C C   . TYR B 2 215 ? 109.124 105.815 98.644  1.00 106.40 ? 215 TYR B C   1 
ATOM 4150 O O   . TYR B 2 215 ? 109.348 106.375 99.729  1.00 106.40 ? 215 TYR B O   1 
ATOM 4151 C CB  . TYR B 2 215 ? 110.027 107.053 96.645  1.00 106.40 ? 215 TYR B CB  1 
ATOM 4152 C CG  . TYR B 2 215 ? 111.310 107.454 95.949  1.00 106.40 ? 215 TYR B CG  1 
ATOM 4153 C CD1 . TYR B 2 215 ? 112.378 107.987 96.665  1.00 106.40 ? 215 TYR B CD1 1 
ATOM 4154 C CD2 . TYR B 2 215 ? 111.455 107.294 94.573  1.00 106.40 ? 215 TYR B CD2 1 
ATOM 4155 C CE1 . TYR B 2 215 ? 113.556 108.353 96.029  1.00 106.40 ? 215 TYR B CE1 1 
ATOM 4156 C CE2 . TYR B 2 215 ? 112.627 107.656 93.928  1.00 106.40 ? 215 TYR B CE2 1 
ATOM 4157 C CZ  . TYR B 2 215 ? 113.671 108.184 94.661  1.00 106.40 ? 215 TYR B CZ  1 
ATOM 4158 O OH  . TYR B 2 215 ? 114.834 108.544 94.024  1.00 106.40 ? 215 TYR B OH  1 
ATOM 4159 N N   . VAL B 2 216 ? 107.974 105.176 98.391  1.00 107.05 ? 216 VAL B N   1 
ATOM 4160 C CA  . VAL B 2 216 ? 106.978 104.978 99.447  1.00 107.05 ? 216 VAL B CA  1 
ATOM 4161 C C   . VAL B 2 216 ? 107.521 104.036 100.523 1.00 107.05 ? 216 VAL B C   1 
ATOM 4162 O O   . VAL B 2 216 ? 107.288 104.237 101.721 1.00 107.05 ? 216 VAL B O   1 
ATOM 4163 C CB  . VAL B 2 216 ? 105.649 104.483 98.837  1.00 107.05 ? 216 VAL B CB  1 
ATOM 4164 C CG1 . VAL B 2 216 ? 104.597 104.166 99.897  1.00 107.05 ? 216 VAL B CG1 1 
ATOM 4165 C CG2 . VAL B 2 216 ? 105.103 105.520 97.872  1.00 107.05 ? 216 VAL B CG2 1 
ATOM 4166 N N   . GLY B 2 217 ? 108.321 103.044 100.125 1.00 109.08 ? 217 GLY B N   1 
ATOM 4167 C CA  . GLY B 2 217 ? 108.983 102.197 101.104 1.00 109.08 ? 217 GLY B CA  1 
ATOM 4168 C C   . GLY B 2 217 ? 110.089 102.916 101.853 1.00 109.08 ? 217 GLY B C   1 
ATOM 4169 O O   . GLY B 2 217 ? 110.425 102.553 102.979 1.00 109.08 ? 217 GLY B O   1 
ATOM 4170 N N   . ARG B 2 218 ? 110.658 103.958 101.241 1.00 110.68 ? 218 ARG B N   1 
ATOM 4171 C CA  . ARG B 2 218 ? 111.613 104.795 101.969 1.00 110.68 ? 218 ARG B CA  1 
ATOM 4172 C C   . ARG B 2 218 ? 110.919 105.614 103.044 1.00 110.68 ? 218 ARG B C   1 
ATOM 4173 O O   . ARG B 2 218 ? 111.343 105.625 104.216 1.00 110.68 ? 218 ARG B O   1 
ATOM 4174 C CB  . ARG B 2 218 ? 112.380 105.691 100.992 1.00 110.68 ? 218 ARG B CB  1 
ATOM 4175 C CG  . ARG B 2 218 ? 113.285 104.939 99.986  1.00 110.68 ? 218 ARG B CG  1 
ATOM 4176 C CD  . ARG B 2 218 ? 114.272 104.066 100.719 1.00 110.68 ? 218 ARG B CD  1 
ATOM 4177 N NE  . ARG B 2 218 ? 113.808 102.686 100.845 1.00 110.68 ? 218 ARG B NE  1 
ATOM 4178 C CZ  . ARG B 2 218 ? 114.145 101.925 101.869 1.00 110.68 ? 218 ARG B CZ  1 
ATOM 4179 N NH1 . ARG B 2 218 ? 114.953 102.378 102.808 1.00 110.68 ? 218 ARG B NH1 1 
ATOM 4180 N NH2 . ARG B 2 218 ? 113.663 100.689 101.955 1.00 110.68 ? 218 ARG B NH2 1 
ATOM 4181 N N   . LYS B 2 219 ? 109.777 106.204 102.690 1.00 112.05 ? 219 LYS B N   1 
ATOM 4182 C CA  . LYS B 2 219 ? 109.004 106.964 103.666 1.00 112.05 ? 219 LYS B CA  1 
ATOM 4183 C C   . LYS B 2 219 ? 108.295 106.031 104.654 1.00 112.05 ? 219 LYS B C   1 
ATOM 4184 O O   . LYS B 2 219 ? 107.790 106.478 105.689 1.00 112.05 ? 219 LYS B O   1 
ATOM 4185 C CB  . LYS B 2 219 ? 108.010 107.873 102.936 1.00 112.05 ? 219 LYS B CB  1 
ATOM 4186 C CG  . LYS B 2 219 ? 107.523 109.067 103.754 1.00 112.05 ? 219 LYS B CG  1 
ATOM 4187 C CD  . LYS B 2 219 ? 106.672 110.014 102.939 1.00 112.05 ? 219 LYS B CD  1 
ATOM 4188 C CE  . LYS B 2 219 ? 105.992 111.034 103.838 1.00 112.05 ? 219 LYS B CE  1 
ATOM 4189 N NZ  . LYS B 2 219 ? 106.975 111.901 104.552 1.00 112.05 ? 219 LYS B NZ  1 
ATOM 4190 N N   . ALA B 2 220 ? 108.264 104.725 104.362 1.00 109.27 ? 220 ALA B N   1 
ATOM 4191 C CA  . ALA B 2 220 ? 107.661 103.776 105.287 1.00 109.27 ? 220 ALA B CA  1 
ATOM 4192 C C   . ALA B 2 220 ? 108.698 103.092 106.183 1.00 109.27 ? 220 ALA B C   1 
ATOM 4193 O O   . ALA B 2 220 ? 108.353 102.642 107.278 1.00 109.27 ? 220 ALA B O   1 
ATOM 4194 C CB  . ALA B 2 220 ? 106.837 102.749 104.512 1.00 109.27 ? 220 ALA B CB  1 
ATOM 4195 N N   . MET B 2 221 ? 109.964 102.969 105.752 1.00 110.56 ? 221 MET B N   1 
ATOM 4196 C CA  . MET B 2 221 ? 111.000 102.597 106.722 1.00 110.56 ? 221 MET B CA  1 
ATOM 4197 C C   . MET B 2 221 ? 111.204 103.725 107.723 1.00 110.56 ? 221 MET B C   1 
ATOM 4198 O O   . MET B 2 221 ? 111.198 103.500 108.943 1.00 110.56 ? 221 MET B O   1 
ATOM 4199 C CB  . MET B 2 221 ? 112.337 102.213 106.063 1.00 110.56 ? 221 MET B CB  1 
ATOM 4200 C CG  . MET B 2 221 ? 113.438 102.053 107.156 1.00 110.56 ? 221 MET B CG  1 
ATOM 4201 S SD  . MET B 2 221 ? 115.219 101.732 107.039 1.00 110.56 ? 221 MET B SD  1 
ATOM 4202 C CE  . MET B 2 221 ? 115.423 100.702 105.615 1.00 110.56 ? 221 MET B CE  1 
ATOM 4203 N N   . PHE B 2 222 ? 111.258 104.964 107.230 1.00 110.99 ? 222 PHE B N   1 
ATOM 4204 C CA  . PHE B 2 222 ? 111.236 106.072 108.173 1.00 110.99 ? 222 PHE B CA  1 
ATOM 4205 C C   . PHE B 2 222 ? 109.823 106.259 108.727 1.00 110.99 ? 222 PHE B C   1 
ATOM 4206 O O   . PHE B 2 222 ? 108.869 105.655 108.233 1.00 110.99 ? 222 PHE B O   1 
ATOM 4207 C CB  . PHE B 2 222 ? 111.811 107.329 107.524 1.00 110.99 ? 222 PHE B CB  1 
ATOM 4208 C CG  . PHE B 2 222 ? 113.280 107.210 107.238 1.00 110.99 ? 222 PHE B CG  1 
ATOM 4209 C CD1 . PHE B 2 222 ? 114.205 107.276 108.274 1.00 110.99 ? 222 PHE B CD1 1 
ATOM 4210 C CD2 . PHE B 2 222 ? 113.732 106.969 105.950 1.00 110.99 ? 222 PHE B CD2 1 
ATOM 4211 C CE1 . PHE B 2 222 ? 115.560 107.147 108.026 1.00 110.99 ? 222 PHE B CE1 1 
ATOM 4212 C CE2 . PHE B 2 222 ? 115.087 106.834 105.692 1.00 110.99 ? 222 PHE B CE2 1 
ATOM 4213 C CZ  . PHE B 2 222 ? 115.999 106.916 106.734 1.00 110.99 ? 222 PHE B CZ  1 
ATOM 4214 N N   . ASP B 2 223 ? 109.760 106.990 109.855 1.00 118.79 ? 223 ASP B N   1 
ATOM 4215 C CA  . ASP B 2 223 ? 108.669 107.104 110.855 1.00 118.79 ? 223 ASP B CA  1 
ATOM 4216 C C   . ASP B 2 223 ? 107.863 105.810 111.090 1.00 118.79 ? 223 ASP B C   1 
ATOM 4217 O O   . ASP B 2 223 ? 106.635 105.848 111.182 1.00 118.79 ? 223 ASP B O   1 
ATOM 4218 C CB  . ASP B 2 223 ? 107.752 108.344 110.663 1.00 118.79 ? 223 ASP B CB  1 
ATOM 4219 C CG  . ASP B 2 223 ? 106.937 108.421 109.354 1.00 118.79 ? 223 ASP B CG  1 
ATOM 4220 O OD1 . ASP B 2 223 ? 106.963 107.611 108.433 1.00 118.79 ? 223 ASP B OD1 1 
ATOM 4221 O OD2 . ASP B 2 223 ? 106.216 109.430 109.250 1.00 118.79 ? 223 ASP B OD2 1 
ATOM 4222 N N   . SER B 2 224 ? 108.570 104.668 111.180 1.00 117.45 ? 224 SER B N   1 
ATOM 4223 C CA  . SER B 2 224 ? 108.138 103.441 111.884 1.00 117.45 ? 224 SER B CA  1 
ATOM 4224 C C   . SER B 2 224 ? 106.894 102.779 111.289 1.00 117.45 ? 224 SER B C   1 
ATOM 4225 O O   . SER B 2 224 ? 105.904 102.543 111.982 1.00 117.45 ? 224 SER B O   1 
ATOM 4226 C CB  . SER B 2 224 ? 107.932 103.714 113.376 1.00 117.45 ? 224 SER B CB  1 
ATOM 4227 O OG  . SER B 2 224 ? 109.142 104.084 114.011 1.00 117.45 ? 224 SER B OG  1 
ATOM 4228 N N   . ASP B 2 225 ? 106.967 102.430 110.005 1.00 117.20 ? 225 ASP B N   1 
ATOM 4229 C CA  . ASP B 2 225 ? 105.876 101.767 109.295 1.00 117.20 ? 225 ASP B CA  1 
ATOM 4230 C C   . ASP B 2 225 ? 106.390 100.551 108.526 1.00 117.20 ? 225 ASP B C   1 
ATOM 4231 O O   . ASP B 2 225 ? 106.160 100.454 107.315 1.00 117.20 ? 225 ASP B O   1 
ATOM 4232 C CB  . ASP B 2 225 ? 105.191 102.742 108.332 1.00 117.20 ? 225 ASP B CB  1 
ATOM 4233 C CG  . ASP B 2 225 ? 104.521 103.907 109.040 1.00 117.20 ? 225 ASP B CG  1 
ATOM 4234 O OD1 . ASP B 2 225 ? 104.006 103.725 110.161 1.00 117.20 ? 225 ASP B OD1 1 
ATOM 4235 O OD2 . ASP B 2 225 ? 104.521 105.019 108.473 1.00 117.20 ? 225 ASP B OD2 1 
ATOM 4236 N N   . PHE B 2 226 ? 107.100 99.642  109.214 1.00 112.59 ? 226 PHE B N   1 
ATOM 4237 C CA  . PHE B 2 226 ? 108.012 98.695  108.559 1.00 112.59 ? 226 PHE B CA  1 
ATOM 4238 C C   . PHE B 2 226 ? 107.287 97.656  107.702 1.00 112.59 ? 226 PHE B C   1 
ATOM 4239 O O   . PHE B 2 226 ? 107.888 97.062  106.800 1.00 112.59 ? 226 PHE B O   1 
ATOM 4240 C CB  . PHE B 2 226 ? 108.872 97.987  109.606 1.00 112.59 ? 226 PHE B CB  1 
ATOM 4241 C CG  . PHE B 2 226 ? 109.868 98.879  110.286 1.00 112.59 ? 226 PHE B CG  1 
ATOM 4242 C CD1 . PHE B 2 226 ? 110.742 99.663  109.545 1.00 112.59 ? 226 PHE B CD1 1 
ATOM 4243 C CD2 . PHE B 2 226 ? 109.942 98.918  111.671 1.00 112.59 ? 226 PHE B CD2 1 
ATOM 4244 C CE1 . PHE B 2 226 ? 111.667 100.483 110.177 1.00 112.59 ? 226 PHE B CE1 1 
ATOM 4245 C CE2 . PHE B 2 226 ? 110.862 99.732  112.310 1.00 112.59 ? 226 PHE B CE2 1 
ATOM 4246 C CZ  . PHE B 2 226 ? 111.725 100.515 111.562 1.00 112.59 ? 226 PHE B CZ  1 
ATOM 4247 N N   . LYS B 2 227 ? 106.003 97.411  107.973 1.00 116.78 ? 227 LYS B N   1 
ATOM 4248 C CA  . LYS B 2 227 ? 105.264 96.427  107.183 1.00 116.78 ? 227 LYS B CA  1 
ATOM 4249 C C   . LYS B 2 227 ? 104.931 96.967  105.794 1.00 116.78 ? 227 LYS B C   1 
ATOM 4250 O O   . LYS B 2 227 ? 104.994 96.230  104.796 1.00 116.78 ? 227 LYS B O   1 
ATOM 4251 C CB  . LYS B 2 227 ? 103.991 96.014  107.922 1.00 116.78 ? 227 LYS B CB  1 
ATOM 4252 C CG  . LYS B 2 227 ? 103.250 94.837  107.303 1.00 116.78 ? 227 LYS B CG  1 
ATOM 4253 C CD  . LYS B 2 227 ? 104.181 93.664  107.042 1.00 116.78 ? 227 LYS B CD  1 
ATOM 4254 C CE  . LYS B 2 227 ? 103.442 92.504  106.407 1.00 116.78 ? 227 LYS B CE  1 
ATOM 4255 N NZ  . LYS B 2 227 ? 103.977 91.196  106.873 1.00 116.78 ? 227 LYS B NZ  1 
ATOM 4256 N N   . GLN B 2 228 ? 104.575 98.257  105.722 1.00 125.89 ? 228 GLN B N   1 
ATOM 4257 C CA  . GLN B 2 228 ? 104.246 98.900  104.452 1.00 125.89 ? 228 GLN B CA  1 
ATOM 4258 C C   . GLN B 2 228 ? 105.462 98.979  103.538 1.00 125.89 ? 228 GLN B C   1 
ATOM 4259 O O   . GLN B 2 228 ? 105.346 98.759  102.325 1.00 125.89 ? 228 GLN B O   1 
ATOM 4260 C CB  . GLN B 2 228 ? 103.687 100.299 104.710 1.00 125.89 ? 228 GLN B CB  1 
ATOM 4261 C CG  . GLN B 2 228 ? 102.406 100.333 105.530 1.00 125.89 ? 228 GLN B CG  1 
ATOM 4262 C CD  . GLN B 2 228 ? 101.251 99.637  104.842 1.00 125.89 ? 228 GLN B CD  1 
ATOM 4263 O OE1 . GLN B 2 228 ? 100.805 98.575  105.273 1.00 125.89 ? 228 GLN B OE1 1 
ATOM 4264 N NE2 . GLN B 2 228 ? 100.756 100.240 103.767 1.00 125.89 ? 228 GLN B NE2 1 
ATOM 4265 N N   . ALA B 2 229 ? 106.635 99.274  104.116 1.00 114.05 ? 229 ALA B N   1 
ATOM 4266 C CA  . ALA B 2 229 ? 107.891 99.270  103.369 1.00 114.05 ? 229 ALA B CA  1 
ATOM 4267 C C   . ALA B 2 229 ? 108.210 97.885  102.830 1.00 114.05 ? 229 ALA B C   1 
ATOM 4268 O O   . ALA B 2 229 ? 108.637 97.748  101.675 1.00 114.05 ? 229 ALA B O   1 
ATOM 4269 C CB  . ALA B 2 229 ? 109.034 99.758  104.259 1.00 114.05 ? 229 ALA B CB  1 
ATOM 4270 N N   . GLU B 2 230 ? 107.953 96.851  103.642 1.00 113.63 ? 230 GLU B N   1 
ATOM 4271 C CA  . GLU B 2 230 ? 108.238 95.473  103.254 1.00 113.63 ? 230 GLU B CA  1 
ATOM 4272 C C   . GLU B 2 230 ? 107.369 95.030  102.088 1.00 113.63 ? 230 GLU B C   1 
ATOM 4273 O O   . GLU B 2 230 ? 107.883 94.493  101.105 1.00 113.63 ? 230 GLU B O   1 
ATOM 4274 C CB  . GLU B 2 230 ? 108.042 94.536  104.445 1.00 113.63 ? 230 GLU B CB  1 
ATOM 4275 C CG  . GLU B 2 230 ? 108.731 93.191  104.285 1.00 113.63 ? 230 GLU B CG  1 
ATOM 4276 C CD  . GLU B 2 230 ? 107.820 92.120  103.712 1.00 113.63 ? 230 GLU B CD  1 
ATOM 4277 O OE1 . GLU B 2 230 ? 108.326 91.037  103.354 1.00 113.63 ? 230 GLU B OE1 1 
ATOM 4278 O OE2 . GLU B 2 230 ? 106.600 92.366  103.610 1.00 113.63 ? 230 GLU B OE2 1 
ATOM 4279 N N   . GLU B 2 231 ? 106.059 95.298  102.152 1.00 124.54 ? 231 GLU B N   1 
ATOM 4280 C CA  . GLU B 2 231 ? 105.184 94.895  101.050 1.00 124.54 ? 231 GLU B CA  1 
ATOM 4281 C C   . GLU B 2 231 ? 105.424 95.740  99.791  1.00 124.54 ? 231 GLU B C   1 
ATOM 4282 O O   . GLU B 2 231 ? 105.615 95.189  98.694  1.00 124.54 ? 231 GLU B O   1 
ATOM 4283 C CB  . GLU B 2 231 ? 103.714 94.899  101.510 1.00 124.54 ? 231 GLU B CB  1 
ATOM 4284 C CG  . GLU B 2 231 ? 103.064 96.231  101.909 1.00 124.54 ? 231 GLU B CG  1 
ATOM 4285 C CD  . GLU B 2 231 ? 101.642 96.063  102.394 1.00 124.54 ? 231 GLU B CD  1 
ATOM 4286 O OE1 . GLU B 2 231 ? 101.162 94.911  102.444 1.00 124.54 ? 231 GLU B OE1 1 
ATOM 4287 O OE2 . GLU B 2 231 ? 101.003 97.083  102.729 1.00 124.54 ? 231 GLU B OE2 1 
ATOM 4288 N N   . TYR B 2 232 ? 105.550 97.067  99.946  1.00 121.59 ? 232 TYR B N   1 
ATOM 4289 C CA  . TYR B 2 232 ? 105.645 97.947  98.788  1.00 121.59 ? 232 TYR B CA  1 
ATOM 4290 C C   . TYR B 2 232 ? 107.023 97.909  98.144  1.00 121.59 ? 232 TYR B C   1 
ATOM 4291 O O   . TYR B 2 232 ? 107.186 98.368  97.009  1.00 121.59 ? 232 TYR B O   1 
ATOM 4292 C CB  . TYR B 2 232 ? 105.280 99.381  99.177  1.00 121.59 ? 232 TYR B CB  1 
ATOM 4293 C CG  . TYR B 2 232 ? 103.795 99.665  99.253  1.00 121.59 ? 232 TYR B CG  1 
ATOM 4294 C CD1 . TYR B 2 232 ? 102.967 99.405  98.163  1.00 121.59 ? 232 TYR B CD1 1 
ATOM 4295 C CD2 . TYR B 2 232 ? 103.227 100.233 100.390 1.00 121.59 ? 232 TYR B CD2 1 
ATOM 4296 C CE1 . TYR B 2 232 ? 101.607 99.679  98.213  1.00 121.59 ? 232 TYR B CE1 1 
ATOM 4297 C CE2 . TYR B 2 232 ? 101.866 100.510 100.451 1.00 121.59 ? 232 TYR B CE2 1 
ATOM 4298 C CZ  . TYR B 2 232 ? 101.065 100.231 99.360  1.00 121.59 ? 232 TYR B CZ  1 
ATOM 4299 O OH  . TYR B 2 232 ? 99.717  100.506 99.421  1.00 121.59 ? 232 TYR B OH  1 
ATOM 4300 N N   . LEU B 2 233 ? 108.032 97.362  98.826  1.00 107.43 ? 233 LEU B N   1 
ATOM 4301 C CA  . LEU B 2 233 ? 109.328 97.314  98.170  1.00 107.43 ? 233 LEU B CA  1 
ATOM 4302 C C   . LEU B 2 233 ? 109.767 95.870  97.925  1.00 107.43 ? 233 LEU B C   1 
ATOM 4303 O O   . LEU B 2 233 ? 110.645 95.621  97.091  1.00 107.43 ? 233 LEU B O   1 
ATOM 4304 C CB  . LEU B 2 233 ? 110.314 98.154  98.985  1.00 107.43 ? 233 LEU B CB  1 
ATOM 4305 C CG  . LEU B 2 233 ? 111.813 98.241  98.754  1.00 107.43 ? 233 LEU B CG  1 
ATOM 4306 C CD1 . LEU B 2 233 ? 112.229 99.662  99.022  1.00 107.43 ? 233 LEU B CD1 1 
ATOM 4307 C CD2 . LEU B 2 233 ? 112.518 97.358  99.699  1.00 107.43 ? 233 LEU B CD2 1 
ATOM 4308 N N   . SER B 2 234 ? 109.094 94.895  98.547  1.00 111.49 ? 234 SER B N   1 
ATOM 4309 C CA  . SER B 2 234 ? 109.215 93.513  98.101  1.00 111.49 ? 234 SER B CA  1 
ATOM 4310 C C   . SER B 2 234 ? 108.494 93.306  96.777  1.00 111.49 ? 234 SER B C   1 
ATOM 4311 O O   . SER B 2 234 ? 108.866 92.424  95.991  1.00 111.49 ? 234 SER B O   1 
ATOM 4312 C CB  . SER B 2 234 ? 108.662 92.569  99.168  1.00 111.49 ? 234 SER B CB  1 
ATOM 4313 O OG  . SER B 2 234 ? 108.436 91.275  98.639  1.00 111.49 ? 234 SER B OG  1 
ATOM 4314 N N   . PHE B 2 235 ? 107.450 94.109  96.517  1.00 119.24 ? 235 PHE B N   1 
ATOM 4315 C CA  . PHE B 2 235 ? 106.854 94.138  95.182  1.00 119.24 ? 235 PHE B CA  1 
ATOM 4316 C C   . PHE B 2 235 ? 107.840 94.674  94.146  1.00 119.24 ? 235 PHE B C   1 
ATOM 4317 O O   . PHE B 2 235 ? 107.822 94.256  92.983  1.00 119.24 ? 235 PHE B O   1 
ATOM 4318 C CB  . PHE B 2 235 ? 105.580 94.986  95.204  1.00 119.24 ? 235 PHE B CB  1 
ATOM 4319 C CG  . PHE B 2 235 ? 104.607 94.668  94.096  1.00 119.24 ? 235 PHE B CG  1 
ATOM 4320 C CD1 . PHE B 2 235 ? 103.572 93.767  94.307  1.00 119.24 ? 235 PHE B CD1 1 
ATOM 4321 C CD2 . PHE B 2 235 ? 104.716 95.282  92.855  1.00 119.24 ? 235 PHE B CD2 1 
ATOM 4322 C CE1 . PHE B 2 235 ? 102.665 93.479  93.296  1.00 119.24 ? 235 PHE B CE1 1 
ATOM 4323 C CE2 . PHE B 2 235 ? 103.813 95.006  91.842  1.00 119.24 ? 235 PHE B CE2 1 
ATOM 4324 C CZ  . PHE B 2 235 ? 102.789 94.099  92.062  1.00 119.24 ? 235 PHE B CZ  1 
ATOM 4325 N N   . ALA B 2 236 ? 108.706 95.608  94.551  1.00 111.70 ? 236 ALA B N   1 
ATOM 4326 C CA  . ALA B 2 236 ? 109.733 96.113  93.645  1.00 111.70 ? 236 ALA B CA  1 
ATOM 4327 C C   . ALA B 2 236 ? 110.863 95.106  93.468  1.00 111.70 ? 236 ALA B C   1 
ATOM 4328 O O   . ALA B 2 236 ? 111.439 94.993  92.379  1.00 111.70 ? 236 ALA B O   1 
ATOM 4329 C CB  . ALA B 2 236 ? 110.279 97.442  94.162  1.00 111.70 ? 236 ALA B CB  1 
ATOM 4330 N N   . PHE B 2 237 ? 111.204 94.376  94.534  1.00 110.88 ? 237 PHE B N   1 
ATOM 4331 C CA  . PHE B 2 237 ? 112.296 93.409  94.450  1.00 110.88 ? 237 PHE B CA  1 
ATOM 4332 C C   . PHE B 2 237 ? 111.895 92.165  93.667  1.00 110.88 ? 237 PHE B C   1 
ATOM 4333 O O   . PHE B 2 237 ? 112.744 91.527  93.032  1.00 110.88 ? 237 PHE B O   1 
ATOM 4334 C CB  . PHE B 2 237 ? 112.776 93.017  95.847  1.00 110.88 ? 237 PHE B CB  1 
ATOM 4335 C CG  . PHE B 2 237 ? 114.011 92.159  95.835  1.00 110.88 ? 237 PHE B CG  1 
ATOM 4336 C CD1 . PHE B 2 237 ? 115.111 92.521  95.070  1.00 110.88 ? 237 PHE B CD1 1 
ATOM 4337 C CD2 . PHE B 2 237 ? 114.061 90.980  96.566  1.00 110.88 ? 237 PHE B CD2 1 
ATOM 4338 C CE1 . PHE B 2 237 ? 116.249 91.734  95.046  1.00 110.88 ? 237 PHE B CE1 1 
ATOM 4339 C CE2 . PHE B 2 237 ? 115.197 90.184  96.547  1.00 110.88 ? 237 PHE B CE2 1 
ATOM 4340 C CZ  . PHE B 2 237 ? 116.291 90.563  95.783  1.00 110.88 ? 237 PHE B CZ  1 
ATOM 4341 N N   . GLU B 2 238 ? 110.613 91.788  93.714  1.00 121.93 ? 238 GLU B N   1 
ATOM 4342 C CA  . GLU B 2 238 ? 110.170 90.623  92.950  1.00 121.93 ? 238 GLU B CA  1 
ATOM 4343 C C   . GLU B 2 238 ? 110.154 90.917  91.454  1.00 121.93 ? 238 GLU B C   1 
ATOM 4344 O O   . GLU B 2 238 ? 110.423 90.033  90.632  1.00 121.93 ? 238 GLU B O   1 
ATOM 4345 C CB  . GLU B 2 238 ? 108.783 90.173  93.426  1.00 121.93 ? 238 GLU B CB  1 
ATOM 4346 C CG  . GLU B 2 238 ? 108.101 88.911  92.776  1.00 121.93 ? 238 GLU B CG  1 
ATOM 4347 C CD  . GLU B 2 238 ? 108.917 87.601  92.580  1.00 121.93 ? 238 GLU B CD  1 
ATOM 4348 O OE1 . GLU B 2 238 ? 108.296 86.655  92.053  1.00 121.93 ? 238 GLU B OE1 1 
ATOM 4349 O OE2 . GLU B 2 238 ? 110.080 87.424  93.014  1.00 121.93 ? 238 GLU B OE2 1 
ATOM 4350 N N   . HIS B 2 239 ? 109.855 92.157  91.088  1.00 121.68 ? 239 HIS B N   1 
ATOM 4351 C CA  . HIS B 2 239 ? 109.871 92.617  89.708  1.00 121.68 ? 239 HIS B CA  1 
ATOM 4352 C C   . HIS B 2 239 ? 111.240 93.205  89.367  1.00 121.68 ? 239 HIS B C   1 
ATOM 4353 O O   . HIS B 2 239 ? 112.252 92.819  89.950  1.00 121.68 ? 239 HIS B O   1 
ATOM 4354 C CB  . HIS B 2 239 ? 108.725 93.595  89.471  1.00 121.68 ? 239 HIS B CB  1 
ATOM 4355 C CG  . HIS B 2 239 ? 107.375 92.978  89.651  1.00 121.68 ? 239 HIS B CG  1 
ATOM 4356 N ND1 . HIS B 2 239 ? 106.753 92.886  90.877  1.00 121.68 ? 239 HIS B ND1 1 
ATOM 4357 C CD2 . HIS B 2 239 ? 106.536 92.402  88.759  1.00 121.68 ? 239 HIS B CD2 1 
ATOM 4358 C CE1 . HIS B 2 239 ? 105.586 92.285  90.731  1.00 121.68 ? 239 HIS B CE1 1 
ATOM 4359 N NE2 . HIS B 2 239 ? 105.428 91.984  89.455  1.00 121.68 ? 239 HIS B NE2 1 
ATOM 4360 N N   . CYS B 2 240 ? 111.262 93.993  88.282  1.00 122.41 ? 240 CYS B N   1 
ATOM 4361 C CA  . CYS B 2 240 ? 112.232 94.956  87.732  1.00 122.41 ? 240 CYS B CA  1 
ATOM 4362 C C   . CYS B 2 240 ? 113.230 94.256  86.816  1.00 122.41 ? 240 CYS B C   1 
ATOM 4363 O O   . CYS B 2 240 ? 113.484 93.055  86.951  1.00 122.41 ? 240 CYS B O   1 
ATOM 4364 C CB  . CYS B 2 240 ? 113.003 95.812  88.767  1.00 122.41 ? 240 CYS B CB  1 
ATOM 4365 S SG  . CYS B 2 240 ? 114.304 95.175  89.874  1.00 122.41 ? 240 CYS B SG  1 
ATOM 4366 N N   . HIS B 2 241 ? 113.788 95.022  85.877  1.00 124.35 ? 241 HIS B N   1 
ATOM 4367 C CA  . HIS B 2 241 ? 114.563 94.477  84.767  1.00 124.35 ? 241 HIS B CA  1 
ATOM 4368 C C   . HIS B 2 241 ? 115.944 94.038  85.243  1.00 124.35 ? 241 HIS B C   1 
ATOM 4369 O O   . HIS B 2 241 ? 116.566 94.706  86.075  1.00 124.35 ? 241 HIS B O   1 
ATOM 4370 C CB  . HIS B 2 241 ? 114.682 95.530  83.665  1.00 124.35 ? 241 HIS B CB  1 
ATOM 4371 C CG  . HIS B 2 241 ? 114.794 94.964  82.282  1.00 124.35 ? 241 HIS B CG  1 
ATOM 4372 N ND1 . HIS B 2 241 ? 115.718 94.001  81.938  1.00 124.35 ? 241 HIS B ND1 1 
ATOM 4373 C CD2 . HIS B 2 241 ? 114.096 95.233  81.154  1.00 124.35 ? 241 HIS B CD2 1 
ATOM 4374 C CE1 . HIS B 2 241 ? 115.584 93.700  80.659  1.00 124.35 ? 241 HIS B CE1 1 
ATOM 4375 N NE2 . HIS B 2 241 ? 114.605 94.434  80.160  1.00 124.35 ? 241 HIS B NE2 1 
ATOM 4376 N N   . ARG B 2 242 ? 116.424 92.913  84.708  1.00 125.25 ? 242 ARG B N   1 
ATOM 4377 C CA  . ARG B 2 242 ? 117.736 92.385  85.057  1.00 125.25 ? 242 ARG B CA  1 
ATOM 4378 C C   . ARG B 2 242 ? 118.863 92.996  84.234  1.00 125.25 ? 242 ARG B C   1 
ATOM 4379 O O   . ARG B 2 242 ? 120.024 92.636  84.454  1.00 125.25 ? 242 ARG B O   1 
ATOM 4380 C CB  . ARG B 2 242 ? 117.751 90.867  84.876  1.00 125.25 ? 242 ARG B CB  1 
ATOM 4381 C CG  . ARG B 2 242 ? 117.637 90.430  83.423  1.00 125.25 ? 242 ARG B CG  1 
ATOM 4382 C CD  . ARG B 2 242 ? 117.541 88.920  83.289  1.00 125.25 ? 242 ARG B CD  1 
ATOM 4383 N NE  . ARG B 2 242 ? 117.530 88.503  81.892  1.00 125.25 ? 242 ARG B NE  1 
ATOM 4384 C CZ  . ARG B 2 242 ? 116.436 88.405  81.148  1.00 125.25 ? 242 ARG B CZ  1 
ATOM 4385 N NH1 . ARG B 2 242 ? 115.239 88.678  81.639  1.00 125.25 ? 242 ARG B NH1 1 
ATOM 4386 N NH2 . ARG B 2 242 ? 116.547 88.024  79.878  1.00 125.25 ? 242 ARG B NH2 1 
ATOM 4387 N N   . SER B 2 243 ? 118.551 93.885  83.287  1.00 122.66 ? 243 SER B N   1 
ATOM 4388 C CA  . SER B 2 243 ? 119.578 94.454  82.419  1.00 122.66 ? 243 SER B CA  1 
ATOM 4389 C C   . SER B 2 243 ? 120.450 95.453  83.172  1.00 122.66 ? 243 SER B C   1 
ATOM 4390 O O   . SER B 2 243 ? 121.681 95.433  83.061  1.00 122.66 ? 243 SER B O   1 
ATOM 4391 C CB  . SER B 2 243 ? 118.927 95.113  81.202  1.00 122.66 ? 243 SER B CB  1 
ATOM 4392 O OG  . SER B 2 243 ? 119.841 95.966  80.535  1.00 122.66 ? 243 SER B OG  1 
ATOM 4393 N N   . SER B 2 244 ? 119.826 96.336  83.946  1.00 116.54 ? 244 SER B N   1 
ATOM 4394 C CA  . SER B 2 244 ? 120.563 97.312  84.746  1.00 116.54 ? 244 SER B CA  1 
ATOM 4395 C C   . SER B 2 244 ? 120.867 96.694  86.103  1.00 116.54 ? 244 SER B C   1 
ATOM 4396 O O   . SER B 2 244 ? 119.983 96.560  86.951  1.00 116.54 ? 244 SER B O   1 
ATOM 4397 C CB  . SER B 2 244 ? 119.760 98.599  84.891  1.00 116.54 ? 244 SER B CB  1 
ATOM 4398 O OG  . SER B 2 244 ? 120.201 99.350  86.007  1.00 116.54 ? 244 SER B OG  1 
ATOM 4399 N N   . GLN B 2 245 ? 122.127 96.312  86.317  1.00 115.18 ? 245 GLN B N   1 
ATOM 4400 C CA  . GLN B 2 245 ? 122.530 95.619  87.542  1.00 115.18 ? 245 GLN B CA  1 
ATOM 4401 C C   . GLN B 2 245 ? 123.075 96.617  88.566  1.00 115.18 ? 245 GLN B C   1 
ATOM 4402 O O   . GLN B 2 245 ? 124.160 96.462  89.130  1.00 115.18 ? 245 GLN B O   1 
ATOM 4403 C CB  . GLN B 2 245 ? 123.550 94.535  87.222  1.00 115.18 ? 245 GLN B CB  1 
ATOM 4404 C CG  . GLN B 2 245 ? 123.086 93.541  86.171  1.00 115.18 ? 245 GLN B CG  1 
ATOM 4405 C CD  . GLN B 2 245 ? 123.807 93.716  84.849  1.00 115.18 ? 245 GLN B CD  1 
ATOM 4406 O OE1 . GLN B 2 245 ? 124.251 94.814  84.511  1.00 115.18 ? 245 GLN B OE1 1 
ATOM 4407 N NE2 . GLN B 2 245 ? 123.928 92.632  84.093  1.00 115.18 ? 245 GLN B NE2 1 
ATOM 4408 N N   . LYS B 2 246 ? 122.287 97.664  88.804  1.00 103.55 ? 246 LYS B N   1 
ATOM 4409 C CA  . LYS B 2 246 ? 122.563 98.596  89.889  1.00 103.55 ? 246 LYS B CA  1 
ATOM 4410 C C   . LYS B 2 246 ? 121.284 98.817  90.684  1.00 103.55 ? 246 LYS B C   1 
ATOM 4411 O O   . LYS B 2 246 ? 121.326 99.062  91.895  1.00 103.55 ? 246 LYS B O   1 
ATOM 4412 C CB  . LYS B 2 246 ? 123.106 99.921  89.347  1.00 103.55 ? 246 LYS B CB  1 
ATOM 4413 C CG  . LYS B 2 246 ? 123.721 100.825 90.413  1.00 103.55 ? 246 LYS B CG  1 
ATOM 4414 C CD  . LYS B 2 246 ? 123.875 102.277 89.959  1.00 103.55 ? 246 LYS B CD  1 
ATOM 4415 C CE  . LYS B 2 246 ? 124.425 102.400 88.543  1.00 103.55 ? 246 LYS B CE  1 
ATOM 4416 N NZ  . LYS B 2 246 ? 124.828 103.797 88.226  1.00 103.55 ? 246 LYS B NZ  1 
ATOM 4417 N N   . ASN B 2 247 ? 120.144 98.694  89.995  1.00 105.25 ? 247 ASN B N   1 
ATOM 4418 C CA  . ASN B 2 247 ? 118.838 98.841  90.632  1.00 105.25 ? 247 ASN B CA  1 
ATOM 4419 C C   . ASN B 2 247 ? 118.570 97.717  91.622  1.00 105.25 ? 247 ASN B C   1 
ATOM 4420 O O   . ASN B 2 247 ? 118.035 97.959  92.709  1.00 105.25 ? 247 ASN B O   1 
ATOM 4421 C CB  . ASN B 2 247 ? 117.744 98.880  89.568  1.00 105.25 ? 247 ASN B CB  1 
ATOM 4422 C CG  . ASN B 2 247 ? 117.979 99.956  88.533  1.00 105.25 ? 247 ASN B CG  1 
ATOM 4423 O OD1 . ASN B 2 247 ? 118.647 100.953 88.802  1.00 105.25 ? 247 ASN B OD1 1 
ATOM 4424 N ND2 . ASN B 2 247 ? 117.430 99.762  87.340  1.00 105.25 ? 247 ASN B ND2 1 
ATOM 4425 N N   . LYS B 2 248 ? 118.961 96.491  91.264  1.00 101.65 ? 248 LYS B N   1 
ATOM 4426 C CA  . LYS B 2 248 ? 118.770 95.337  92.137  1.00 101.65 ? 248 LYS B CA  1 
ATOM 4427 C C   . LYS B 2 248 ? 119.633 95.427  93.391  1.00 101.65 ? 248 LYS B C   1 
ATOM 4428 O O   . LYS B 2 248 ? 119.193 95.043  94.478  1.00 101.65 ? 248 LYS B O   1 
ATOM 4429 C CB  . LYS B 2 248 ? 119.077 94.062  91.355  1.00 101.65 ? 248 LYS B CB  1 
ATOM 4430 C CG  . LYS B 2 248 ? 118.643 94.147  89.896  1.00 101.65 ? 248 LYS B CG  1 
ATOM 4431 C CD  . LYS B 2 248 ? 118.954 92.882  89.111  1.00 101.65 ? 248 LYS B CD  1 
ATOM 4432 C CE  . LYS B 2 248 ? 120.413 92.481  89.258  1.00 101.65 ? 248 LYS B CE  1 
ATOM 4433 N NZ  . LYS B 2 248 ? 120.689 91.156  88.625  1.00 101.65 ? 248 LYS B NZ  1 
ATOM 4434 N N   . ARG B 2 249 ? 120.857 95.946  93.261  1.00 97.01  ? 249 ARG B N   1 
ATOM 4435 C CA  . ARG B 2 249 ? 121.719 96.144  94.425  1.00 97.01  ? 249 ARG B CA  1 
ATOM 4436 C C   . ARG B 2 249 ? 121.211 97.277  95.311  1.00 97.01  ? 249 ARG B C   1 
ATOM 4437 O O   . ARG B 2 249 ? 121.204 97.162  96.547  1.00 97.01  ? 249 ARG B O   1 
ATOM 4438 C CB  . ARG B 2 249 ? 123.147 96.430  93.966  1.00 97.01  ? 249 ARG B CB  1 
ATOM 4439 C CG  . ARG B 2 249 ? 124.177 96.400  95.077  1.00 97.01  ? 249 ARG B CG  1 
ATOM 4440 C CD  . ARG B 2 249 ? 125.345 97.304  94.719  1.00 97.01  ? 249 ARG B CD  1 
ATOM 4441 N NE  . ARG B 2 249 ? 126.581 96.932  95.395  1.00 97.01  ? 249 ARG B NE  1 
ATOM 4442 C CZ  . ARG B 2 249 ? 127.133 97.629  96.380  1.00 97.01  ? 249 ARG B CZ  1 
ATOM 4443 N NH1 . ARG B 2 249 ? 126.582 98.745  96.830  1.00 97.01  ? 249 ARG B NH1 1 
ATOM 4444 N NH2 . ARG B 2 249 ? 128.268 97.199  96.922  1.00 97.01  ? 249 ARG B NH2 1 
ATOM 4445 N N   . MET B 2 250 ? 120.783 98.382  94.685  1.00 102.01 ? 250 MET B N   1 
ATOM 4446 C CA  . MET B 2 250 ? 120.334 99.564  95.414  1.00 102.01 ? 250 MET B CA  1 
ATOM 4447 C C   . MET B 2 250 ? 119.007 99.290  96.117  1.00 102.01 ? 250 MET B C   1 
ATOM 4448 O O   . MET B 2 250 ? 118.721 99.879  97.166  1.00 102.01 ? 250 MET B O   1 
ATOM 4449 C CB  . MET B 2 250 ? 120.249 100.731 94.413  1.00 102.01 ? 250 MET B CB  1 
ATOM 4450 C CG  . MET B 2 250 ? 119.436 102.004 94.728  1.00 102.01 ? 250 MET B CG  1 
ATOM 4451 S SD  . MET B 2 250 ? 119.556 102.847 96.329  1.00 102.01 ? 250 MET B SD  1 
ATOM 4452 C CE  . MET B 2 250 ? 121.328 102.963 96.581  1.00 102.01 ? 250 MET B CE  1 
ATOM 4453 N N   . ILE B 2 251 ? 118.213 98.356  95.583  1.00 97.35  ? 251 ILE B N   1 
ATOM 4454 C CA  . ILE B 2 251 ? 117.046 97.856  96.304  1.00 97.35  ? 251 ILE B CA  1 
ATOM 4455 C C   . ILE B 2 251 ? 117.472 97.085  97.554  1.00 97.35  ? 251 ILE B C   1 
ATOM 4456 O O   . ILE B 2 251 ? 116.871 97.248  98.619  1.00 97.35  ? 251 ILE B O   1 
ATOM 4457 C CB  . ILE B 2 251 ? 116.162 97.021  95.350  1.00 97.35  ? 251 ILE B CB  1 
ATOM 4458 C CG1 . ILE B 2 251 ? 115.275 97.950  94.518  1.00 97.35  ? 251 ILE B CG1 1 
ATOM 4459 C CG2 . ILE B 2 251 ? 115.274 96.018  96.083  1.00 97.35  ? 251 ILE B CG2 1 
ATOM 4460 C CD1 . ILE B 2 251 ? 114.479 97.243  93.448  1.00 97.35  ? 251 ILE B CD1 1 
ATOM 4461 N N   . LEU B 2 252 ? 118.556 96.296  97.467  1.00 100.04 ? 252 LEU B N   1 
ATOM 4462 C CA  . LEU B 2 252 ? 118.970 95.450  98.594  1.00 100.04 ? 252 LEU B CA  1 
ATOM 4463 C C   . LEU B 2 252 ? 119.541 96.248  99.760  1.00 100.04 ? 252 LEU B C   1 
ATOM 4464 O O   . LEU B 2 252 ? 119.267 95.914  100.926 1.00 100.04 ? 252 LEU B O   1 
ATOM 4465 C CB  . LEU B 2 252 ? 120.009 94.426  98.162  1.00 100.04 ? 252 LEU B CB  1 
ATOM 4466 C CG  . LEU B 2 252 ? 119.651 93.288  97.232  1.00 100.04 ? 252 LEU B CG  1 
ATOM 4467 C CD1 . LEU B 2 252 ? 120.943 92.608  96.917  1.00 100.04 ? 252 LEU B CD1 1 
ATOM 4468 C CD2 . LEU B 2 252 ? 118.685 92.343  97.906  1.00 100.04 ? 252 LEU B CD2 1 
ATOM 4469 N N   . ILE B 2 253 ? 120.358 97.274  99.456  1.00 96.20  ? 253 ILE B N   1 
ATOM 4470 C CA  . ILE B 2 253 ? 121.003 98.169  100.430 1.00 96.20  ? 253 ILE B CA  1 
ATOM 4471 C C   . ILE B 2 253 ? 119.967 98.796  101.354 1.00 96.20  ? 253 ILE B C   1 
ATOM 4472 O O   . ILE B 2 253 ? 120.142 98.845  102.578 1.00 96.20  ? 253 ILE B O   1 
ATOM 4473 C CB  . ILE B 2 253 ? 121.823 99.274  99.724  1.00 96.20  ? 253 ILE B CB  1 
ATOM 4474 C CG1 . ILE B 2 253 ? 122.924 98.693  98.841  1.00 96.20  ? 253 ILE B CG1 1 
ATOM 4475 C CG2 . ILE B 2 253 ? 122.441 100.252 100.713 1.00 96.20  ? 253 ILE B CG2 1 
ATOM 4476 C CD1 . ILE B 2 253 ? 123.937 97.884  99.599  1.00 96.20  ? 253 ILE B CD1 1 
ATOM 4477 N N   . TYR B 2 254 ? 118.851 99.207  100.772 1.00 100.09 ? 254 TYR B N   1 
ATOM 4478 C CA  . TYR B 2 254 ? 117.747 99.801  101.503 1.00 100.09 ? 254 TYR B CA  1 
ATOM 4479 C C   . TYR B 2 254 ? 116.621 98.820  101.832 1.00 100.09 ? 254 TYR B C   1 
ATOM 4480 O O   . TYR B 2 254 ? 115.669 99.204  102.519 1.00 100.09 ? 254 TYR B O   1 
ATOM 4481 C CB  . TYR B 2 254 ? 117.215 100.996 100.708 1.00 100.09 ? 254 TYR B CB  1 
ATOM 4482 C CG  . TYR B 2 254 ? 118.132 102.202 100.620 1.00 100.09 ? 254 TYR B CG  1 
ATOM 4483 C CD1 . TYR B 2 254 ? 119.231 102.338 101.464 1.00 100.09 ? 254 TYR B CD1 1 
ATOM 4484 C CD2 . TYR B 2 254 ? 117.863 103.233 99.724  1.00 100.09 ? 254 TYR B CD2 1 
ATOM 4485 C CE1 . TYR B 2 254 ? 120.054 103.440 101.391 1.00 100.09 ? 254 TYR B CE1 1 
ATOM 4486 C CE2 . TYR B 2 254 ? 118.682 104.347 99.647  1.00 100.09 ? 254 TYR B CE2 1 
ATOM 4487 C CZ  . TYR B 2 254 ? 119.774 104.443 100.485 1.00 100.09 ? 254 TYR B CZ  1 
ATOM 4488 O OH  . TYR B 2 254 ? 120.595 105.544 100.419 1.00 100.09 ? 254 TYR B OH  1 
ATOM 4489 N N   . LEU B 2 255 ? 116.712 97.569  101.376 1.00 96.22  ? 255 LEU B N   1 
ATOM 4490 C CA  . LEU B 2 255 ? 115.750 96.498  101.633 1.00 96.22  ? 255 LEU B CA  1 
ATOM 4491 C C   . LEU B 2 255 ? 116.037 95.697  102.888 1.00 96.22  ? 255 LEU B C   1 
ATOM 4492 O O   . LEU B 2 255 ? 115.090 95.329  103.594 1.00 96.22  ? 255 LEU B O   1 
ATOM 4493 C CB  . LEU B 2 255 ? 115.714 95.532  100.439 1.00 96.22  ? 255 LEU B CB  1 
ATOM 4494 C CG  . LEU B 2 255 ? 115.032 94.144  100.461 1.00 96.22  ? 255 LEU B CG  1 
ATOM 4495 C CD1 . LEU B 2 255 ? 113.573 94.056  100.907 1.00 96.22  ? 255 LEU B CD1 1 
ATOM 4496 C CD2 . LEU B 2 255 ? 115.185 93.504  99.087  1.00 96.22  ? 255 LEU B CD2 1 
ATOM 4497 N N   . LEU B 2 256 ? 117.313 95.395  103.145 1.00 93.36  ? 256 LEU B N   1 
ATOM 4498 C CA  . LEU B 2 256 ? 117.677 94.382  104.141 1.00 93.36  ? 256 LEU B CA  1 
ATOM 4499 C C   . LEU B 2 256 ? 117.247 94.671  105.588 1.00 93.36  ? 256 LEU B C   1 
ATOM 4500 O O   . LEU B 2 256 ? 116.632 93.773  106.189 1.00 93.36  ? 256 LEU B O   1 
ATOM 4501 C CB  . LEU B 2 256 ? 119.183 94.094  104.037 1.00 93.36  ? 256 LEU B CB  1 
ATOM 4502 C CG  . LEU B 2 256 ? 119.550 93.113  102.923 1.00 93.36  ? 256 LEU B CG  1 
ATOM 4503 C CD1 . LEU B 2 256 ? 121.042 92.859  102.919 1.00 93.36  ? 256 LEU B CD1 1 
ATOM 4504 C CD2 . LEU B 2 256 ? 118.776 91.815  103.053 1.00 93.36  ? 256 LEU B CD2 1 
ATOM 4505 N N   . PRO B 2 257 ? 117.461 95.866  106.191 1.00 92.89  ? 257 PRO B N   1 
ATOM 4506 C CA  . PRO B 2 257 ? 117.035 96.023  107.598 1.00 92.89  ? 257 PRO B CA  1 
ATOM 4507 C C   . PRO B 2 257 ? 115.529 96.099  107.812 1.00 92.89  ? 257 PRO B C   1 
ATOM 4508 O O   . PRO B 2 257 ? 115.089 95.964  108.960 1.00 92.89  ? 257 PRO B O   1 
ATOM 4509 C CB  . PRO B 2 257 ? 117.723 97.328  108.028 1.00 92.89  ? 257 PRO B CB  1 
ATOM 4510 C CG  . PRO B 2 257 ? 118.815 97.502  107.063 1.00 92.89  ? 257 PRO B CG  1 
ATOM 4511 C CD  . PRO B 2 257 ? 118.186 97.091  105.793 1.00 92.89  ? 257 PRO B CD  1 
ATOM 4512 N N   . VAL B 2 258 ? 114.736 96.299  106.752 1.00 100.65 ? 258 VAL B N   1 
ATOM 4513 C CA  . VAL B 2 258 ? 113.284 96.171  106.860 1.00 100.65 ? 258 VAL B CA  1 
ATOM 4514 C C   . VAL B 2 258 ? 112.908 94.744  107.238 1.00 100.65 ? 258 VAL B C   1 
ATOM 4515 O O   . VAL B 2 258 ? 112.095 94.518  108.143 1.00 100.65 ? 258 VAL B O   1 
ATOM 4516 C CB  . VAL B 2 258 ? 112.608 96.602  105.543 1.00 100.65 ? 258 VAL B CB  1 
ATOM 4517 C CG1 . VAL B 2 258 ? 111.117 96.334  105.581 1.00 100.65 ? 258 VAL B CG1 1 
ATOM 4518 C CG2 . VAL B 2 258 ? 112.852 98.060  105.274 1.00 100.65 ? 258 VAL B CG2 1 
ATOM 4519 N N   . LYS B 2 259 ? 113.544 93.761  106.603 1.00 99.01  ? 259 LYS B N   1 
ATOM 4520 C CA  . LYS B 2 259 ? 113.238 92.379  106.932 1.00 99.01  ? 259 LYS B CA  1 
ATOM 4521 C C   . LYS B 2 259 ? 114.113 91.836  108.058 1.00 99.01  ? 259 LYS B C   1 
ATOM 4522 O O   . LYS B 2 259 ? 113.843 90.733  108.547 1.00 99.01  ? 259 LYS B O   1 
ATOM 4523 C CB  . LYS B 2 259 ? 113.348 91.517  105.677 1.00 99.01  ? 259 LYS B CB  1 
ATOM 4524 C CG  . LYS B 2 259 ? 112.286 91.868  104.646 1.00 99.01  ? 259 LYS B CG  1 
ATOM 4525 C CD  . LYS B 2 259 ? 112.397 91.027  103.398 1.00 99.01  ? 259 LYS B CD  1 
ATOM 4526 C CE  . LYS B 2 259 ? 111.928 89.615  103.680 1.00 99.01  ? 259 LYS B CE  1 
ATOM 4527 N NZ  . LYS B 2 259 ? 110.462 89.572  103.932 1.00 99.01  ? 259 LYS B NZ  1 
ATOM 4528 N N   . MET B 2 260 ? 115.154 92.566  108.483 1.00 94.55  ? 260 MET B N   1 
ATOM 4529 C CA  . MET B 2 260 ? 115.764 92.216  109.768 1.00 94.55  ? 260 MET B CA  1 
ATOM 4530 C C   . MET B 2 260 ? 114.931 92.692  110.957 1.00 94.55  ? 260 MET B C   1 
ATOM 4531 O O   . MET B 2 260 ? 114.850 91.984  111.967 1.00 94.55  ? 260 MET B O   1 
ATOM 4532 C CB  . MET B 2 260 ? 117.196 92.746  109.887 1.00 94.55  ? 260 MET B CB  1 
ATOM 4533 C CG  . MET B 2 260 ? 118.113 92.451  108.730 1.00 94.55  ? 260 MET B CG  1 
ATOM 4534 S SD  . MET B 2 260 ? 119.085 90.965  109.021 1.00 94.55  ? 260 MET B SD  1 
ATOM 4535 C CE  . MET B 2 260 ? 120.551 91.675  109.762 1.00 94.55  ? 260 MET B CE  1 
ATOM 4536 N N   . LEU B 2 261 ? 114.325 93.884  110.881 1.00 97.31  ? 261 LEU B N   1 
ATOM 4537 C CA  . LEU B 2 261 ? 113.366 94.258  111.921 1.00 97.31  ? 261 LEU B CA  1 
ATOM 4538 C C   . LEU B 2 261 ? 112.084 93.436  111.843 1.00 97.31  ? 261 LEU B C   1 
ATOM 4539 O O   . LEU B 2 261 ? 111.463 93.170  112.878 1.00 97.31  ? 261 LEU B O   1 
ATOM 4540 C CB  . LEU B 2 261 ? 113.042 95.758  111.885 1.00 97.31  ? 261 LEU B CB  1 
ATOM 4541 C CG  . LEU B 2 261 ? 113.923 96.820  112.570 1.00 97.31  ? 261 LEU B CG  1 
ATOM 4542 C CD1 . LEU B 2 261 ? 113.910 96.592  114.082 1.00 97.31  ? 261 LEU B CD1 1 
ATOM 4543 C CD2 . LEU B 2 261 ? 115.355 96.927  112.076 1.00 97.31  ? 261 LEU B CD2 1 
ATOM 4544 N N   . LEU B 2 262 ? 111.668 93.020  110.643 1.00 103.36 ? 262 LEU B N   1 
ATOM 4545 C CA  . LEU B 2 262 ? 110.502 92.147  110.556 1.00 103.36 ? 262 LEU B CA  1 
ATOM 4546 C C   . LEU B 2 262 ? 110.852 90.719  110.961 1.00 103.36 ? 262 LEU B C   1 
ATOM 4547 O O   . LEU B 2 262 ? 110.032 90.031  111.580 1.00 103.36 ? 262 LEU B O   1 
ATOM 4548 C CB  . LEU B 2 262 ? 109.914 92.179  109.142 1.00 103.36 ? 262 LEU B CB  1 
ATOM 4549 C CG  . LEU B 2 262 ? 108.637 91.364  108.913 1.00 103.36 ? 262 LEU B CG  1 
ATOM 4550 C CD1 . LEU B 2 262 ? 107.511 91.913  109.780 1.00 103.36 ? 262 LEU B CD1 1 
ATOM 4551 C CD2 . LEU B 2 262 ? 108.234 91.327  107.457 1.00 103.36 ? 262 LEU B CD2 1 
ATOM 4552 N N   . GLY B 2 263 ? 112.065 90.266  110.654 1.00 101.92 ? 263 GLY B N   1 
ATOM 4553 C CA  . GLY B 2 263 ? 112.508 88.976  111.143 1.00 101.92 ? 263 GLY B CA  1 
ATOM 4554 C C   . GLY B 2 263 ? 113.078 88.023  110.112 1.00 101.92 ? 263 GLY B C   1 
ATOM 4555 O O   . GLY B 2 263 ? 114.003 87.267  110.420 1.00 101.92 ? 263 GLY B O   1 
ATOM 4556 N N   . HIS B 2 264 ? 112.542 88.026  108.894 1.00 108.31 ? 264 HIS B N   1 
ATOM 4557 C CA  . HIS B 2 264 ? 112.940 87.053  107.880 1.00 108.31 ? 264 HIS B CA  1 
ATOM 4558 C C   . HIS B 2 264 ? 114.147 87.588  107.116 1.00 108.31 ? 264 HIS B C   1 
ATOM 4559 O O   . HIS B 2 264 ? 113.998 88.285  106.107 1.00 108.31 ? 264 HIS B O   1 
ATOM 4560 C CB  . HIS B 2 264 ? 111.775 86.738  106.943 1.00 108.31 ? 264 HIS B CB  1 
ATOM 4561 C CG  . HIS B 2 264 ? 110.592 86.121  107.630 1.00 108.31 ? 264 HIS B CG  1 
ATOM 4562 N ND1 . HIS B 2 264 ? 109.380 85.939  107.000 1.00 108.31 ? 264 HIS B ND1 1 
ATOM 4563 C CD2 . HIS B 2 264 ? 110.439 85.632  108.884 1.00 108.31 ? 264 HIS B CD2 1 
ATOM 4564 C CE1 . HIS B 2 264 ? 108.530 85.373  107.837 1.00 108.31 ? 264 HIS B CE1 1 
ATOM 4565 N NE2 . HIS B 2 264 ? 109.147 85.177  108.988 1.00 108.31 ? 264 HIS B NE2 1 
ATOM 4566 N N   . MET B 2 265 ? 115.356 87.233  107.591 1.00 100.24 ? 265 MET B N   1 
ATOM 4567 C CA  . MET B 2 265 ? 116.756 87.509  107.303 1.00 100.24 ? 265 MET B CA  1 
ATOM 4568 C C   . MET B 2 265 ? 117.216 86.802  106.030 1.00 100.24 ? 265 MET B C   1 
ATOM 4569 O O   . MET B 2 265 ? 116.699 85.733  105.693 1.00 100.24 ? 265 MET B O   1 
ATOM 4570 C CB  . MET B 2 265 ? 117.620 87.060  108.482 1.00 100.24 ? 265 MET B CB  1 
ATOM 4571 C CG  . MET B 2 265 ? 117.266 87.736  109.787 1.00 100.24 ? 265 MET B CG  1 
ATOM 4572 S SD  . MET B 2 265 ? 117.976 86.926  111.234 1.00 100.24 ? 265 MET B SD  1 
ATOM 4573 C CE  . MET B 2 265 ? 119.448 86.169  110.546 1.00 100.24 ? 265 MET B CE  1 
ATOM 4574 N N   . PRO B 2 266 ? 118.183 87.360  105.293 1.00 108.09 ? 266 PRO B N   1 
ATOM 4575 C CA  . PRO B 2 266 ? 118.599 86.738  104.029 1.00 108.09 ? 266 PRO B CA  1 
ATOM 4576 C C   . PRO B 2 266 ? 119.444 85.493  104.246 1.00 108.09 ? 266 PRO B C   1 
ATOM 4577 O O   . PRO B 2 266 ? 119.920 85.196  105.344 1.00 108.09 ? 266 PRO B O   1 
ATOM 4578 C CB  . PRO B 2 266 ? 119.420 87.837  103.351 1.00 108.09 ? 266 PRO B CB  1 
ATOM 4579 C CG  . PRO B 2 266 ? 119.986 88.596  104.482 1.00 108.09 ? 266 PRO B CG  1 
ATOM 4580 C CD  . PRO B 2 266 ? 118.868 88.655  105.482 1.00 108.09 ? 266 PRO B CD  1 
ATOM 4581 N N   . THR B 2 267 ? 119.614 84.753  103.156 1.00 112.45 ? 267 THR B N   1 
ATOM 4582 C CA  . THR B 2 267 ? 120.497 83.601  103.117 1.00 112.45 ? 267 THR B CA  1 
ATOM 4583 C C   . THR B 2 267 ? 121.895 84.016  102.664 1.00 112.45 ? 267 THR B C   1 
ATOM 4584 O O   . THR B 2 267 ? 122.187 85.194  102.447 1.00 112.45 ? 267 THR B O   1 
ATOM 4585 C CB  . THR B 2 267 ? 119.926 82.519  102.198 1.00 112.45 ? 267 THR B CB  1 
ATOM 4586 O OG1 . THR B 2 267 ? 120.721 81.330  102.301 1.00 112.45 ? 267 THR B OG1 1 
ATOM 4587 C CG2 . THR B 2 267 ? 119.877 82.992  100.744 1.00 112.45 ? 267 THR B CG2 1 
ATOM 4588 N N   . VAL B 2 268 ? 122.770 83.018  102.526 1.00 118.47 ? 268 VAL B N   1 
ATOM 4589 C CA  . VAL B 2 268 ? 124.153 83.286  102.153 1.00 118.47 ? 268 VAL B CA  1 
ATOM 4590 C C   . VAL B 2 268 ? 124.291 83.386  100.634 1.00 118.47 ? 268 VAL B C   1 
ATOM 4591 O O   . VAL B 2 268 ? 125.182 84.084  100.130 1.00 118.47 ? 268 VAL B O   1 
ATOM 4592 C CB  . VAL B 2 268 ? 125.057 82.188  102.756 1.00 118.47 ? 268 VAL B CB  1 
ATOM 4593 C CG1 . VAL B 2 268 ? 126.543 82.547  102.666 1.00 118.47 ? 268 VAL B CG1 1 
ATOM 4594 C CG2 . VAL B 2 268 ? 124.660 81.911  104.201 1.00 118.47 ? 268 VAL B CG2 1 
ATOM 4595 N N   . GLU B 2 269 ? 123.387 82.741  99.886  1.00 121.09 ? 269 GLU B N   1 
ATOM 4596 C CA  . GLU B 2 269 ? 123.566 82.573  98.442  1.00 121.09 ? 269 GLU B CA  1 
ATOM 4597 C C   . GLU B 2 269 ? 123.339 83.872  97.673  1.00 121.09 ? 269 GLU B C   1 
ATOM 4598 O O   . GLU B 2 269 ? 124.067 84.159  96.714  1.00 121.09 ? 269 GLU B O   1 
ATOM 4599 C CB  . GLU B 2 269 ? 122.631 81.481  97.924  1.00 121.09 ? 269 GLU B CB  1 
ATOM 4600 C CG  . GLU B 2 269 ? 122.925 80.098  98.478  1.00 121.09 ? 269 GLU B CG  1 
ATOM 4601 C CD  . GLU B 2 269 ? 124.248 79.543  97.987  1.00 121.09 ? 269 GLU B CD  1 
ATOM 4602 O OE1 . GLU B 2 269 ? 124.614 79.811  96.822  1.00 121.09 ? 269 GLU B OE1 1 
ATOM 4603 O OE2 . GLU B 2 269 ? 124.923 78.838  98.765  1.00 121.09 ? 269 GLU B OE2 1 
ATOM 4604 N N   . LEU B 2 270 ? 122.337 84.664  98.071  1.00 118.93 ? 270 LEU B N   1 
ATOM 4605 C CA  . LEU B 2 270 ? 122.110 85.959  97.431  1.00 118.93 ? 270 LEU B CA  1 
ATOM 4606 C C   . LEU B 2 270 ? 123.237 86.939  97.738  1.00 118.93 ? 270 LEU B C   1 
ATOM 4607 O O   . LEU B 2 270 ? 123.620 87.731  96.869  1.00 118.93 ? 270 LEU B O   1 
ATOM 4608 C CB  . LEU B 2 270 ? 120.737 86.511  97.850  1.00 118.93 ? 270 LEU B CB  1 
ATOM 4609 C CG  . LEU B 2 270 ? 120.100 87.774  97.240  1.00 118.93 ? 270 LEU B CG  1 
ATOM 4610 C CD1 . LEU B 2 270 ? 118.600 87.679  97.327  1.00 118.93 ? 270 LEU B CD1 1 
ATOM 4611 C CD2 . LEU B 2 270 ? 120.499 89.044  97.975  1.00 118.93 ? 270 LEU B CD2 1 
ATOM 4612 N N   . LEU B 2 271 ? 123.777 86.893  98.957  1.00 115.49 ? 271 LEU B N   1 
ATOM 4613 C CA  . LEU B 2 271 ? 124.901 87.750  99.311  1.00 115.49 ? 271 LEU B CA  1 
ATOM 4614 C C   . LEU B 2 271 ? 126.182 87.317  98.609  1.00 115.49 ? 271 LEU B C   1 
ATOM 4615 O O   . LEU B 2 271 ? 127.062 88.149  98.358  1.00 115.49 ? 271 LEU B O   1 
ATOM 4616 C CB  . LEU B 2 271 ? 125.090 87.749  100.825 1.00 115.49 ? 271 LEU B CB  1 
ATOM 4617 C CG  . LEU B 2 271 ? 123.840 88.101  101.634 1.00 115.49 ? 271 LEU B CG  1 
ATOM 4618 C CD1 . LEU B 2 271 ? 124.093 87.933  103.123 1.00 115.49 ? 271 LEU B CD1 1 
ATOM 4619 C CD2 . LEU B 2 271 ? 123.385 89.518  101.322 1.00 115.49 ? 271 LEU B CD2 1 
ATOM 4620 N N   . LYS B 2 272 ? 126.305 86.028  98.291  1.00 116.55 ? 272 LYS B N   1 
ATOM 4621 C CA  . LYS B 2 272 ? 127.443 85.559  97.509  1.00 116.55 ? 272 LYS B CA  1 
ATOM 4622 C C   . LYS B 2 272 ? 127.302 85.953  96.044  1.00 116.55 ? 272 LYS B C   1 
ATOM 4623 O O   . LYS B 2 272 ? 128.285 86.327  95.394  1.00 116.55 ? 272 LYS B O   1 
ATOM 4624 C CB  . LYS B 2 272 ? 127.579 84.042  97.641  1.00 116.55 ? 272 LYS B CB  1 
ATOM 4625 C CG  . LYS B 2 272 ? 128.249 83.577  98.919  1.00 116.55 ? 272 LYS B CG  1 
ATOM 4626 C CD  . LYS B 2 272 ? 129.751 83.477  98.744  1.00 116.55 ? 272 LYS B CD  1 
ATOM 4627 C CE  . LYS B 2 272 ? 130.342 82.464  99.705  1.00 116.55 ? 272 LYS B CE  1 
ATOM 4628 N NZ  . LYS B 2 272 ? 129.829 82.660  101.086 1.00 116.55 ? 272 LYS B NZ  1 
ATOM 4629 N N   . LYS B 2 273 ? 126.083 85.866  95.505  1.00 118.42 ? 273 LYS B N   1 
ATOM 4630 C CA  . LYS B 2 273 ? 125.884 86.116  94.081  1.00 118.42 ? 273 LYS B CA  1 
ATOM 4631 C C   . LYS B 2 273 ? 125.924 87.607  93.766  1.00 118.42 ? 273 LYS B C   1 
ATOM 4632 O O   . LYS B 2 273 ? 126.439 88.015  92.718  1.00 118.42 ? 273 LYS B O   1 
ATOM 4633 C CB  . LYS B 2 273 ? 124.562 85.501  93.620  1.00 118.42 ? 273 LYS B CB  1 
ATOM 4634 C CG  . LYS B 2 273 ? 124.398 85.445  92.105  1.00 118.42 ? 273 LYS B CG  1 
ATOM 4635 C CD  . LYS B 2 273 ? 122.967 85.723  91.673  1.00 118.42 ? 273 LYS B CD  1 
ATOM 4636 C CE  . LYS B 2 273 ? 121.969 84.829  92.389  1.00 118.42 ? 273 LYS B CE  1 
ATOM 4637 N NZ  . LYS B 2 273 ? 120.564 85.208  92.080  1.00 118.42 ? 273 LYS B NZ  1 
ATOM 4638 N N   . TYR B 2 274 ? 125.391 88.441  94.656  1.00 111.40 ? 274 TYR B N   1 
ATOM 4639 C CA  . TYR B 2 274 ? 125.353 89.876  94.402  1.00 111.40 ? 274 TYR B CA  1 
ATOM 4640 C C   . TYR B 2 274 ? 126.458 90.629  95.134  1.00 111.40 ? 274 TYR B C   1 
ATOM 4641 O O   . TYR B 2 274 ? 126.374 91.857  95.239  1.00 111.40 ? 274 TYR B O   1 
ATOM 4642 C CB  . TYR B 2 274 ? 123.979 90.456  94.778  1.00 111.40 ? 274 TYR B CB  1 
ATOM 4643 C CG  . TYR B 2 274 ? 122.875 90.268  93.736  1.00 111.40 ? 274 TYR B CG  1 
ATOM 4644 C CD1 . TYR B 2 274 ? 123.017 89.378  92.674  1.00 111.40 ? 274 TYR B CD1 1 
ATOM 4645 C CD2 . TYR B 2 274 ? 121.679 90.971  93.836  1.00 111.40 ? 274 TYR B CD2 1 
ATOM 4646 C CE1 . TYR B 2 274 ? 122.006 89.206  91.739  1.00 111.40 ? 274 TYR B CE1 1 
ATOM 4647 C CE2 . TYR B 2 274 ? 120.660 90.803  92.909  1.00 111.40 ? 274 TYR B CE2 1 
ATOM 4648 C CZ  . TYR B 2 274 ? 120.834 89.918  91.866  1.00 111.40 ? 274 TYR B CZ  1 
ATOM 4649 O OH  . TYR B 2 274 ? 119.833 89.732  90.938  1.00 111.40 ? 274 TYR B OH  1 
ATOM 4650 N N   . HIS B 2 275 ? 127.452 89.902  95.671  1.00 116.43 ? 275 HIS B N   1 
ATOM 4651 C CA  . HIS B 2 275 ? 128.714 90.407  96.259  1.00 116.43 ? 275 HIS B CA  1 
ATOM 4652 C C   . HIS B 2 275 ? 128.504 91.409  97.405  1.00 116.43 ? 275 HIS B C   1 
ATOM 4653 O O   . HIS B 2 275 ? 129.371 92.223  97.731  1.00 116.43 ? 275 HIS B O   1 
ATOM 4654 C CB  . HIS B 2 275 ? 129.671 90.937  95.166  1.00 116.43 ? 275 HIS B CB  1 
ATOM 4655 C CG  . HIS B 2 275 ? 129.355 92.305  94.634  1.00 116.43 ? 275 HIS B CG  1 
ATOM 4656 N ND1 . HIS B 2 275 ? 128.502 92.507  93.570  1.00 116.43 ? 275 HIS B ND1 1 
ATOM 4657 C CD2 . HIS B 2 275 ? 129.817 93.531  94.980  1.00 116.43 ? 275 HIS B CD2 1 
ATOM 4658 C CE1 . HIS B 2 275 ? 128.425 93.799  93.307  1.00 116.43 ? 275 HIS B CE1 1 
ATOM 4659 N NE2 . HIS B 2 275 ? 129.212 94.443  94.149  1.00 116.43 ? 275 HIS B NE2 1 
ATOM 4660 N N   . LEU B 2 276 ? 127.371 91.269  98.098  1.00 106.24 ? 276 LEU B N   1 
ATOM 4661 C CA  . LEU B 2 276 ? 126.992 92.146  99.208  1.00 106.24 ? 276 LEU B CA  1 
ATOM 4662 C C   . LEU B 2 276 ? 127.351 91.405  100.498 1.00 106.24 ? 276 LEU B C   1 
ATOM 4663 O O   . LEU B 2 276 ? 126.521 90.704  101.076 1.00 106.24 ? 276 LEU B O   1 
ATOM 4664 C CB  . LEU B 2 276 ? 125.503 92.492  99.124  1.00 106.24 ? 276 LEU B CB  1 
ATOM 4665 C CG  . LEU B 2 276 ? 124.892 93.667  99.888  1.00 106.24 ? 276 LEU B CG  1 
ATOM 4666 C CD1 . LEU B 2 276 ? 123.736 94.204  99.071  1.00 106.24 ? 276 LEU B CD1 1 
ATOM 4667 C CD2 . LEU B 2 276 ? 124.415 93.276  101.271 1.00 106.24 ? 276 LEU B CD2 1 
ATOM 4668 N N   . MET B 2 277 ? 128.595 91.558  100.950 1.00 107.18 ? 277 MET B N   1 
ATOM 4669 C CA  . MET B 2 277 ? 129.098 90.743  102.050 1.00 107.18 ? 277 MET B CA  1 
ATOM 4670 C C   . MET B 2 277 ? 129.236 91.492  103.371 1.00 107.18 ? 277 MET B C   1 
ATOM 4671 O O   . MET B 2 277 ? 129.729 90.906  104.340 1.00 107.18 ? 277 MET B O   1 
ATOM 4672 C CB  . MET B 2 277 ? 130.453 90.136  101.675 1.00 107.18 ? 277 MET B CB  1 
ATOM 4673 C CG  . MET B 2 277 ? 130.356 88.924  100.764 1.00 107.18 ? 277 MET B CG  1 
ATOM 4674 S SD  . MET B 2 277 ? 130.081 87.398  101.683 1.00 107.18 ? 277 MET B SD  1 
ATOM 4675 C CE  . MET B 2 277 ? 131.724 86.687  101.661 1.00 107.18 ? 277 MET B CE  1 
ATOM 4676 N N   . GLN B 2 278 ? 128.824 92.761  103.442 1.00 102.36 ? 278 GLN B N   1 
ATOM 4677 C CA  . GLN B 2 278 ? 128.967 93.504  104.691 1.00 102.36 ? 278 GLN B CA  1 
ATOM 4678 C C   . GLN B 2 278 ? 127.928 93.091  105.725 1.00 102.36 ? 278 GLN B C   1 
ATOM 4679 O O   . GLN B 2 278 ? 128.236 93.032  106.921 1.00 102.36 ? 278 GLN B O   1 
ATOM 4680 C CB  . GLN B 2 278 ? 128.877 95.008  104.433 1.00 102.36 ? 278 GLN B CB  1 
ATOM 4681 C CG  . GLN B 2 278 ? 130.037 95.578  103.639 1.00 102.36 ? 278 GLN B CG  1 
ATOM 4682 C CD  . GLN B 2 278 ? 129.774 95.599  102.149 1.00 102.36 ? 278 GLN B CD  1 
ATOM 4683 O OE1 . GLN B 2 278 ? 128.628 95.518  101.709 1.00 102.36 ? 278 GLN B OE1 1 
ATOM 4684 N NE2 . GLN B 2 278 ? 130.837 95.712  101.361 1.00 102.36 ? 278 GLN B NE2 1 
ATOM 4685 N N   . PHE B 2 279 ? 126.701 92.798  105.291 1.00 95.20  ? 279 PHE B N   1 
ATOM 4686 C CA  . PHE B 2 279 ? 125.629 92.485  106.229 1.00 95.20  ? 279 PHE B CA  1 
ATOM 4687 C C   . PHE B 2 279 ? 125.701 91.059  106.758 1.00 95.20  ? 279 PHE B C   1 
ATOM 4688 O O   . PHE B 2 279 ? 125.050 90.771  107.769 1.00 95.20  ? 279 PHE B O   1 
ATOM 4689 C CB  . PHE B 2 279 ? 124.269 92.708  105.563 1.00 95.20  ? 279 PHE B CB  1 
ATOM 4690 C CG  . PHE B 2 279 ? 123.817 94.141  105.559 1.00 95.20  ? 279 PHE B CG  1 
ATOM 4691 C CD1 . PHE B 2 279 ? 123.074 94.650  106.615 1.00 95.20  ? 279 PHE B CD1 1 
ATOM 4692 C CD2 . PHE B 2 279 ? 124.138 94.979  104.500 1.00 95.20  ? 279 PHE B CD2 1 
ATOM 4693 C CE1 . PHE B 2 279 ? 122.652 95.972  106.613 1.00 95.20  ? 279 PHE B CE1 1 
ATOM 4694 C CE2 . PHE B 2 279 ? 123.723 96.301  104.490 1.00 95.20  ? 279 PHE B CE2 1 
ATOM 4695 C CZ  . PHE B 2 279 ? 122.980 96.797  105.548 1.00 95.20  ? 279 PHE B CZ  1 
ATOM 4696 N N   . ALA B 2 280 ? 126.503 90.192  106.119 1.00 101.15 ? 280 ALA B N   1 
ATOM 4697 C CA  . ALA B 2 280 ? 126.399 88.741  106.299 1.00 101.15 ? 280 ALA B CA  1 
ATOM 4698 C C   . ALA B 2 280 ? 126.795 88.303  107.705 1.00 101.15 ? 280 ALA B C   1 
ATOM 4699 O O   . ALA B 2 280 ? 126.068 87.538  108.353 1.00 101.15 ? 280 ALA B O   1 
ATOM 4700 C CB  . ALA B 2 280 ? 127.259 88.027  105.257 1.00 101.15 ? 280 ALA B CB  1 
ATOM 4701 N N   . GLU B 2 281 ? 127.923 88.816  108.211 1.00 103.33 ? 281 GLU B N   1 
ATOM 4702 C CA  . GLU B 2 281 ? 128.307 88.546  109.594 1.00 103.33 ? 281 GLU B CA  1 
ATOM 4703 C C   . GLU B 2 281 ? 127.348 89.215  110.574 1.00 103.33 ? 281 GLU B C   1 
ATOM 4704 O O   . GLU B 2 281 ? 127.142 88.713  111.688 1.00 103.33 ? 281 GLU B O   1 
ATOM 4705 C CB  . GLU B 2 281 ? 129.751 88.992  109.842 1.00 103.33 ? 281 GLU B CB  1 
ATOM 4706 C CG  . GLU B 2 281 ? 130.036 90.455  109.539 1.00 103.33 ? 281 GLU B CG  1 
ATOM 4707 C CD  . GLU B 2 281 ? 131.251 90.979  110.276 1.00 103.33 ? 281 GLU B CD  1 
ATOM 4708 O OE1 . GLU B 2 281 ? 132.162 90.178  110.575 1.00 103.33 ? 281 GLU B OE1 1 
ATOM 4709 O OE2 . GLU B 2 281 ? 131.300 92.197  110.547 1.00 103.33 ? 281 GLU B OE2 1 
ATOM 4710 N N   . VAL B 2 282 ? 126.720 90.321  110.150 1.00 96.47  ? 282 VAL B N   1 
ATOM 4711 C CA  . VAL B 2 282 ? 125.638 90.934  110.916 1.00 96.47  ? 282 VAL B CA  1 
ATOM 4712 C C   . VAL B 2 282 ? 124.456 89.976  111.009 1.00 96.47  ? 282 VAL B C   1 
ATOM 4713 O O   . VAL B 2 282 ? 123.838 89.831  112.071 1.00 96.47  ? 282 VAL B O   1 
ATOM 4714 C CB  . VAL B 2 282 ? 125.237 92.281  110.286 1.00 96.47  ? 282 VAL B CB  1 
ATOM 4715 C CG1 . VAL B 2 282 ? 124.219 93.007  111.151 1.00 96.47  ? 282 VAL B CG1 1 
ATOM 4716 C CG2 . VAL B 2 282 ? 126.468 93.146  110.070 1.00 96.47  ? 282 VAL B CG2 1 
ATOM 4717 N N   . THR B 2 283 ? 124.189 89.230  109.925 1.00 102.51 ? 283 THR B N   1 
ATOM 4718 C CA  . THR B 2 283 ? 123.154 88.204  109.983 1.00 102.51 ? 283 THR B CA  1 
ATOM 4719 C C   . THR B 2 283 ? 123.591 86.990  110.796 1.00 102.51 ? 283 THR B C   1 
ATOM 4720 O O   . THR B 2 283 ? 122.744 86.163  111.147 1.00 102.51 ? 283 THR B O   1 
ATOM 4721 C CB  . THR B 2 283 ? 122.735 87.760  108.579 1.00 102.51 ? 283 THR B CB  1 
ATOM 4722 O OG1 . THR B 2 283 ? 123.838 87.135  107.916 1.00 102.51 ? 283 THR B OG1 1 
ATOM 4723 C CG2 . THR B 2 283 ? 122.261 88.950  107.757 1.00 102.51 ? 283 THR B CG2 1 
ATOM 4724 N N   . ARG B 2 284 ? 124.887 86.852  111.091 1.00 100.39 ? 284 ARG B N   1 
ATOM 4725 C CA  . ARG B 2 284 ? 125.287 85.919  112.136 1.00 100.39 ? 284 ARG B CA  1 
ATOM 4726 C C   . ARG B 2 284 ? 124.985 86.489  113.515 1.00 100.39 ? 284 ARG B C   1 
ATOM 4727 O O   . ARG B 2 284 ? 124.515 85.766  114.403 1.00 100.39 ? 284 ARG B O   1 
ATOM 4728 C CB  . ARG B 2 284 ? 126.772 85.581  112.011 1.00 100.39 ? 284 ARG B CB  1 
ATOM 4729 C CG  . ARG B 2 284 ? 127.203 84.429  112.902 1.00 100.39 ? 284 ARG B CG  1 
ATOM 4730 C CD  . ARG B 2 284 ? 128.648 84.034  112.668 1.00 100.39 ? 284 ARG B CD  1 
ATOM 4731 N NE  . ARG B 2 284 ? 128.998 82.839  113.426 1.00 100.39 ? 284 ARG B NE  1 
ATOM 4732 C CZ  . ARG B 2 284 ? 129.466 82.850  114.666 1.00 100.39 ? 284 ARG B CZ  1 
ATOM 4733 N NH1 . ARG B 2 284 ? 129.646 83.982  115.327 1.00 100.39 ? 284 ARG B NH1 1 
ATOM 4734 N NH2 . ARG B 2 284 ? 129.757 81.696  115.260 1.00 100.39 ? 284 ARG B NH2 1 
ATOM 4735 N N   . ALA B 2 285 ? 125.223 87.795  113.697 1.00 101.83 ? 285 ALA B N   1 
ATOM 4736 C CA  . ALA B 2 285 ? 125.163 88.399  115.026 1.00 101.83 ? 285 ALA B CA  1 
ATOM 4737 C C   . ALA B 2 285 ? 123.728 88.534  115.516 1.00 101.83 ? 285 ALA B C   1 
ATOM 4738 O O   . ALA B 2 285 ? 123.472 88.495  116.725 1.00 101.83 ? 285 ALA B O   1 
ATOM 4739 C CB  . ALA B 2 285 ? 125.857 89.760  115.009 1.00 101.83 ? 285 ALA B CB  1 
ATOM 4740 N N   . VAL B 2 286 ? 122.783 88.694  114.589 1.00 93.78  ? 286 VAL B N   1 
ATOM 4741 C CA  . VAL B 2 286 ? 121.372 88.633  114.944 1.00 93.78  ? 286 VAL B CA  1 
ATOM 4742 C C   . VAL B 2 286 ? 120.983 87.200  115.310 1.00 93.78  ? 286 VAL B C   1 
ATOM 4743 O O   . VAL B 2 286 ? 120.163 86.987  116.215 1.00 93.78  ? 286 VAL B O   1 
ATOM 4744 C CB  . VAL B 2 286 ? 120.530 89.215  113.787 1.00 93.78  ? 286 VAL B CB  1 
ATOM 4745 C CG1 . VAL B 2 286 ? 119.025 89.144  114.064 1.00 93.78  ? 286 VAL B CG1 1 
ATOM 4746 C CG2 . VAL B 2 286 ? 120.947 90.650  113.509 1.00 93.78  ? 286 VAL B CG2 1 
ATOM 4747 N N   . SER B 2 287 ? 121.612 86.201  114.665 1.00 94.47  ? 287 SER B N   1 
ATOM 4748 C CA  . SER B 2 287 ? 121.174 84.809  114.791 1.00 94.47  ? 287 SER B CA  1 
ATOM 4749 C C   . SER B 2 287 ? 121.486 84.229  116.169 1.00 94.47  ? 287 SER B C   1 
ATOM 4750 O O   . SER B 2 287 ? 120.637 83.559  116.770 1.00 94.47  ? 287 SER B O   1 
ATOM 4751 C CB  . SER B 2 287 ? 121.830 83.948  113.712 1.00 94.47  ? 287 SER B CB  1 
ATOM 4752 O OG  . SER B 2 287 ? 121.517 84.382  112.408 1.00 94.47  ? 287 SER B OG  1 
ATOM 4753 N N   . GLU B 2 288 ? 122.686 84.474  116.685 1.00 96.56  ? 288 GLU B N   1 
ATOM 4754 C CA  . GLU B 2 288 ? 122.981 84.128  118.070 1.00 96.56  ? 288 GLU B CA  1 
ATOM 4755 C C   . GLU B 2 288 ? 123.476 85.372  118.801 1.00 96.56  ? 288 GLU B C   1 
ATOM 4756 O O   . GLU B 2 288 ? 122.813 85.882  119.705 1.00 96.56  ? 288 GLU B O   1 
ATOM 4757 C CB  . GLU B 2 288 ? 124.023 82.992  118.196 1.00 96.56  ? 288 GLU B CB  1 
ATOM 4758 C CG  . GLU B 2 288 ? 123.817 81.716  117.341 1.00 96.56  ? 288 GLU B CG  1 
ATOM 4759 C CD  . GLU B 2 288 ? 124.287 81.818  115.889 1.00 96.56  ? 288 GLU B CD  1 
ATOM 4760 O OE1 . GLU B 2 288 ? 124.463 82.937  115.369 1.00 96.56  ? 288 GLU B OE1 1 
ATOM 4761 O OE2 . GLU B 2 288 ? 124.469 80.755  115.257 1.00 96.56  ? 288 GLU B OE2 1 
ATOM 4762 N N   . LEU B 2 292 ? 130.492 92.447  122.946 1.00 115.00 ? 292 LEU B N   1 
ATOM 4763 C CA  . LEU B 2 292 ? 129.368 92.087  122.091 1.00 115.00 ? 292 LEU B CA  1 
ATOM 4764 C C   . LEU B 2 292 ? 129.826 91.859  120.657 1.00 115.00 ? 292 LEU B C   1 
ATOM 4765 O O   . LEU B 2 292 ? 130.643 92.612  120.127 1.00 115.00 ? 292 LEU B O   1 
ATOM 4766 C CB  . LEU B 2 292 ? 128.291 93.172  122.133 1.00 115.00 ? 292 LEU B CB  1 
ATOM 4767 N N   . LEU B 2 293 ? 129.296 90.804  120.036 1.00 115.02 ? 293 LEU B N   1 
ATOM 4768 C CA  . LEU B 2 293 ? 129.647 90.508  118.650 1.00 115.02 ? 293 LEU B CA  1 
ATOM 4769 C C   . LEU B 2 293 ? 128.940 91.456  117.687 1.00 115.02 ? 293 LEU B C   1 
ATOM 4770 O O   . LEU B 2 293 ? 129.463 91.755  116.606 1.00 115.02 ? 293 LEU B O   1 
ATOM 4771 C CB  . LEU B 2 293 ? 129.327 89.045  118.319 1.00 115.02 ? 293 LEU B CB  1 
ATOM 4772 C CG  . LEU B 2 293 ? 127.930 88.525  117.942 1.00 115.02 ? 293 LEU B CG  1 
ATOM 4773 C CD1 . LEU B 2 293 ? 128.030 87.069  117.516 1.00 115.02 ? 293 LEU B CD1 1 
ATOM 4774 C CD2 . LEU B 2 293 ? 126.888 88.668  119.052 1.00 115.02 ? 293 LEU B CD2 1 
ATOM 4775 N N   . LEU B 2 294 ? 127.755 91.948  118.072 1.00 107.23 ? 294 LEU B N   1 
ATOM 4776 C CA  . LEU B 2 294 ? 126.999 92.856  117.213 1.00 107.23 ? 294 LEU B CA  1 
ATOM 4777 C C   . LEU B 2 294 ? 127.669 94.221  117.119 1.00 107.23 ? 294 LEU B C   1 
ATOM 4778 O O   . LEU B 2 294 ? 127.778 94.792  116.027 1.00 107.23 ? 294 LEU B O   1 
ATOM 4779 C CB  . LEU B 2 294 ? 125.569 92.999  117.737 1.00 107.23 ? 294 LEU B CB  1 
ATOM 4780 C CG  . LEU B 2 294 ? 124.663 94.022  117.044 1.00 107.23 ? 294 LEU B CG  1 
ATOM 4781 C CD1 . LEU B 2 294 ? 124.477 93.684  115.571 1.00 107.23 ? 294 LEU B CD1 1 
ATOM 4782 C CD2 . LEU B 2 294 ? 123.323 94.131  117.751 1.00 107.23 ? 294 LEU B CD2 1 
ATOM 4783 N N   . HIS B 2 295 ? 128.144 94.749  118.252 1.00 112.10 ? 295 HIS B N   1 
ATOM 4784 C CA  . HIS B 2 295 ? 128.853 96.025  118.267 1.00 112.10 ? 295 HIS B CA  1 
ATOM 4785 C C   . HIS B 2 295 ? 130.196 95.949  117.555 1.00 112.10 ? 295 HIS B C   1 
ATOM 4786 O O   . HIS B 2 295 ? 130.576 96.902  116.866 1.00 112.10 ? 295 HIS B O   1 
ATOM 4787 C CB  . HIS B 2 295 ? 129.053 96.498  119.706 1.00 112.10 ? 295 HIS B CB  1 
ATOM 4788 C CG  . HIS B 2 295 ? 129.395 97.950  119.822 1.00 112.10 ? 295 HIS B CG  1 
ATOM 4789 N ND1 . HIS B 2 295 ? 128.441 98.929  119.999 1.00 112.10 ? 295 HIS B ND1 1 
ATOM 4790 C CD2 . HIS B 2 295 ? 130.589 98.589  119.794 1.00 112.10 ? 295 HIS B CD2 1 
ATOM 4791 C CE1 . HIS B 2 295 ? 129.032 100.109 120.069 1.00 112.10 ? 295 HIS B CE1 1 
ATOM 4792 N NE2 . HIS B 2 295 ? 130.335 99.930  119.949 1.00 112.10 ? 295 HIS B NE2 1 
ATOM 4793 N N   . GLU B 2 296 ? 130.908 94.825  117.696 1.00 116.17 ? 296 GLU B N   1 
ATOM 4794 C CA  . GLU B 2 296 ? 132.174 94.634  116.993 1.00 116.17 ? 296 GLU B CA  1 
ATOM 4795 C C   . GLU B 2 296 ? 131.952 94.516  115.488 1.00 116.17 ? 296 GLU B C   1 
ATOM 4796 O O   . GLU B 2 296 ? 132.710 95.094  114.699 1.00 116.17 ? 296 GLU B O   1 
ATOM 4797 C CB  . GLU B 2 296 ? 132.890 93.400  117.561 1.00 116.17 ? 296 GLU B CB  1 
ATOM 4798 C CG  . GLU B 2 296 ? 134.348 93.161  117.119 1.00 116.17 ? 296 GLU B CG  1 
ATOM 4799 C CD  . GLU B 2 296 ? 134.492 92.434  115.790 1.00 116.17 ? 296 GLU B CD  1 
ATOM 4800 O OE1 . GLU B 2 296 ? 133.591 91.641  115.444 1.00 116.17 ? 296 GLU B OE1 1 
ATOM 4801 O OE2 . GLU B 2 296 ? 135.504 92.660  115.095 1.00 116.17 ? 296 GLU B OE2 1 
ATOM 4802 N N   . ALA B 2 297 ? 130.906 93.788  115.075 1.00 112.64 ? 297 ALA B N   1 
ATOM 4803 C CA  . ALA B 2 297 ? 130.594 93.664  113.654 1.00 112.64 ? 297 ALA B CA  1 
ATOM 4804 C C   . ALA B 2 297 ? 130.090 94.976  113.065 1.00 112.64 ? 297 ALA B C   1 
ATOM 4805 O O   . ALA B 2 297 ? 130.299 95.240  111.876 1.00 112.64 ? 297 ALA B O   1 
ATOM 4806 C CB  . ALA B 2 297 ? 129.563 92.558  113.440 1.00 112.64 ? 297 ALA B CB  1 
ATOM 4807 N N   . LEU B 2 298 ? 129.431 95.807  113.876 1.00 105.57 ? 298 LEU B N   1 
ATOM 4808 C CA  . LEU B 2 298 ? 128.990 97.112  113.401 1.00 105.57 ? 298 LEU B CA  1 
ATOM 4809 C C   . LEU B 2 298 ? 130.162 98.082  113.291 1.00 105.57 ? 298 LEU B C   1 
ATOM 4810 O O   . LEU B 2 298 ? 130.237 98.877  112.347 1.00 105.57 ? 298 LEU B O   1 
ATOM 4811 C CB  . LEU B 2 298 ? 127.911 97.662  114.336 1.00 105.57 ? 298 LEU B CB  1 
ATOM 4812 C CG  . LEU B 2 298 ? 126.945 98.714  113.790 1.00 105.57 ? 298 LEU B CG  1 
ATOM 4813 C CD1 . LEU B 2 298 ? 126.384 98.288  112.444 1.00 105.57 ? 298 LEU B CD1 1 
ATOM 4814 C CD2 . LEU B 2 298 ? 125.822 98.962  114.781 1.00 105.57 ? 298 LEU B CD2 1 
ATOM 4815 N N   . ALA B 2 299 ? 131.091 98.032  114.250 1.00 112.92 ? 299 ALA B N   1 
ATOM 4816 C CA  . ALA B 2 299 ? 132.214 98.961  114.266 1.00 112.92 ? 299 ALA B CA  1 
ATOM 4817 C C   . ALA B 2 299 ? 133.361 98.537  113.358 1.00 112.92 ? 299 ALA B C   1 
ATOM 4818 O O   . ALA B 2 299 ? 134.257 99.350  113.106 1.00 112.92 ? 299 ALA B O   1 
ATOM 4819 C CB  . ALA B 2 299 ? 132.732 99.134  115.695 1.00 112.92 ? 299 ALA B CB  1 
ATOM 4820 N N   . LYS B 2 300 ? 133.374 97.287  112.883 1.00 117.57 ? 300 LYS B N   1 
ATOM 4821 C CA  . LYS B 2 300 ? 134.409 96.879  111.937 1.00 117.57 ? 300 LYS B CA  1 
ATOM 4822 C C   . LYS B 2 300 ? 134.187 97.518  110.569 1.00 117.57 ? 300 LYS B C   1 
ATOM 4823 O O   . LYS B 2 300 ? 135.149 97.841  109.862 1.00 117.57 ? 300 LYS B O   1 
ATOM 4824 C CB  . LYS B 2 300 ? 134.448 95.353  111.831 1.00 117.57 ? 300 LYS B CB  1 
ATOM 4825 C CG  . LYS B 2 300 ? 135.648 94.806  111.070 1.00 117.57 ? 300 LYS B CG  1 
ATOM 4826 C CD  . LYS B 2 300 ? 135.659 93.290  111.065 1.00 117.57 ? 300 LYS B CD  1 
ATOM 4827 C CE  . LYS B 2 300 ? 134.585 92.736  110.146 1.00 117.57 ? 300 LYS B CE  1 
ATOM 4828 N NZ  . LYS B 2 300 ? 134.655 91.253  110.051 1.00 117.57 ? 300 LYS B NZ  1 
ATOM 4829 N N   . HIS B 2 301 ? 132.929 97.731  110.194 1.00 117.84 ? 301 HIS B N   1 
ATOM 4830 C CA  . HIS B 2 301 ? 132.547 98.411  108.960 1.00 117.84 ? 301 HIS B CA  1 
ATOM 4831 C C   . HIS B 2 301 ? 131.689 99.621  109.291 1.00 117.84 ? 301 HIS B C   1 
ATOM 4832 O O   . HIS B 2 301 ? 130.595 99.815  108.757 1.00 117.84 ? 301 HIS B O   1 
ATOM 4833 C CB  . HIS B 2 301 ? 131.821 97.471  108.001 1.00 117.84 ? 301 HIS B CB  1 
ATOM 4834 C CG  . HIS B 2 301 ? 132.673 96.347  107.502 1.00 117.84 ? 301 HIS B CG  1 
ATOM 4835 N ND1 . HIS B 2 301 ? 133.651 96.524  106.548 1.00 117.84 ? 301 HIS B ND1 1 
ATOM 4836 C CD2 . HIS B 2 301 ? 132.691 95.031  107.819 1.00 117.84 ? 301 HIS B CD2 1 
ATOM 4837 C CE1 . HIS B 2 301 ? 134.238 95.367  106.301 1.00 117.84 ? 301 HIS B CE1 1 
ATOM 4838 N NE2 . HIS B 2 301 ? 133.673 94.444  107.059 1.00 117.84 ? 301 HIS B NE2 1 
ATOM 4839 N N   . GLU B 2 302 ? 132.196 100.444 110.214 1.00 112.18 ? 302 GLU B N   1 
ATOM 4840 C CA  . GLU B 2 302 ? 131.494 101.606 110.745 1.00 112.18 ? 302 GLU B CA  1 
ATOM 4841 C C   . GLU B 2 302 ? 131.264 102.700 109.712 1.00 112.18 ? 302 GLU B C   1 
ATOM 4842 O O   . GLU B 2 302 ? 130.287 103.444 109.838 1.00 112.18 ? 302 GLU B O   1 
ATOM 4843 C CB  . GLU B 2 302 ? 132.285 102.183 111.924 1.00 112.18 ? 302 GLU B CB  1 
ATOM 4844 C CG  . GLU B 2 302 ? 131.447 102.896 112.969 1.00 112.18 ? 302 GLU B CG  1 
ATOM 4845 C CD  . GLU B 2 302 ? 131.367 104.391 112.733 1.00 112.18 ? 302 GLU B CD  1 
ATOM 4846 O OE1 . GLU B 2 302 ? 132.242 104.932 112.025 1.00 112.18 ? 302 GLU B OE1 1 
ATOM 4847 O OE2 . GLU B 2 302 ? 130.427 105.023 113.261 1.00 112.18 ? 302 GLU B OE2 1 
ATOM 4848 N N   . ALA B 2 303 ? 132.117 102.807 108.694 1.00 104.80 ? 303 ALA B N   1 
ATOM 4849 C CA  . ALA B 2 303 ? 132.051 103.896 107.729 1.00 104.80 ? 303 ALA B CA  1 
ATOM 4850 C C   . ALA B 2 303 ? 131.179 103.575 106.521 1.00 104.80 ? 303 ALA B C   1 
ATOM 4851 O O   . ALA B 2 303 ? 131.056 104.412 105.621 1.00 104.80 ? 303 ALA B O   1 
ATOM 4852 C CB  . ALA B 2 303 ? 133.460 104.276 107.270 1.00 104.80 ? 303 ALA B CB  1 
ATOM 4853 N N   . PHE B 2 304 ? 130.568 102.391 106.476 1.00 101.22 ? 304 PHE B N   1 
ATOM 4854 C CA  . PHE B 2 304 ? 129.754 101.997 105.333 1.00 101.22 ? 304 PHE B CA  1 
ATOM 4855 C C   . PHE B 2 304 ? 128.281 102.345 105.491 1.00 101.22 ? 304 PHE B C   1 
ATOM 4856 O O   . PHE B 2 304 ? 127.672 102.826 104.530 1.00 101.22 ? 304 PHE B O   1 
ATOM 4857 C CB  . PHE B 2 304 ? 129.895 100.489 105.079 1.00 101.22 ? 304 PHE B CB  1 
ATOM 4858 C CG  . PHE B 2 304 ? 128.996 99.962  103.991 1.00 101.22 ? 304 PHE B CG  1 
ATOM 4859 C CD1 . PHE B 2 304 ? 129.249 100.265 102.660 1.00 101.22 ? 304 PHE B CD1 1 
ATOM 4860 C CD2 . PHE B 2 304 ? 127.916 99.140  104.297 1.00 101.22 ? 304 PHE B CD2 1 
ATOM 4861 C CE1 . PHE B 2 304 ? 128.427 99.776  101.653 1.00 101.22 ? 304 PHE B CE1 1 
ATOM 4862 C CE2 . PHE B 2 304 ? 127.092 98.647  103.297 1.00 101.22 ? 304 PHE B CE2 1 
ATOM 4863 C CZ  . PHE B 2 304 ? 127.349 98.966  101.974 1.00 101.22 ? 304 PHE B CZ  1 
ATOM 4864 N N   . PHE B 2 305 ? 127.700 102.125 106.667 1.00 99.75  ? 305 PHE B N   1 
ATOM 4865 C CA  . PHE B 2 305 ? 126.280 102.371 106.874 1.00 99.75  ? 305 PHE B CA  1 
ATOM 4866 C C   . PHE B 2 305 ? 125.955 103.836 107.131 1.00 99.75  ? 305 PHE B C   1 
ATOM 4867 O O   . PHE B 2 305 ? 124.781 104.214 107.048 1.00 99.75  ? 305 PHE B O   1 
ATOM 4868 C CB  . PHE B 2 305 ? 125.754 101.515 108.034 1.00 99.75  ? 305 PHE B CB  1 
ATOM 4869 C CG  . PHE B 2 305 ? 126.226 100.087 108.000 1.00 99.75  ? 305 PHE B CG  1 
ATOM 4870 C CD1 . PHE B 2 305 ? 127.276 99.662  108.806 1.00 99.75  ? 305 PHE B CD1 1 
ATOM 4871 C CD2 . PHE B 2 305 ? 125.627 99.171  107.147 1.00 99.75  ? 305 PHE B CD2 1 
ATOM 4872 C CE1 . PHE B 2 305 ? 127.708 98.345  108.771 1.00 99.75  ? 305 PHE B CE1 1 
ATOM 4873 C CE2 . PHE B 2 305 ? 126.054 97.853  107.106 1.00 99.75  ? 305 PHE B CE2 1 
ATOM 4874 C CZ  . PHE B 2 305 ? 127.097 97.442  107.919 1.00 99.75  ? 305 PHE B CZ  1 
ATOM 4875 N N   . ILE B 2 306 ? 126.950 104.660 107.446 1.00 110.02 ? 306 ILE B N   1 
ATOM 4876 C CA  . ILE B 2 306 ? 126.748 106.103 107.549 1.00 110.02 ? 306 ILE B CA  1 
ATOM 4877 C C   . ILE B 2 306 ? 126.512 106.719 106.174 1.00 110.02 ? 306 ILE B C   1 
ATOM 4878 O O   . ILE B 2 306 ? 125.649 107.590 106.018 1.00 110.02 ? 306 ILE B O   1 
ATOM 4879 C CB  . ILE B 2 306 ? 127.953 106.744 108.277 1.00 110.02 ? 306 ILE B CB  1 
ATOM 4880 C CG1 . ILE B 2 306 ? 128.051 106.215 109.708 1.00 110.02 ? 306 ILE B CG1 1 
ATOM 4881 C CG2 . ILE B 2 306 ? 127.863 108.265 108.319 1.00 110.02 ? 306 ILE B CG2 1 
ATOM 4882 C CD1 . ILE B 2 306 ? 129.339 106.591 110.408 1.00 110.02 ? 306 ILE B CD1 1 
ATOM 4883 N N   . ARG B 2 307 ? 127.251 106.234 105.168 1.00 112.98 ? 307 ARG B N   1 
ATOM 4884 C CA  . ARG B 2 307 ? 127.185 106.758 103.806 1.00 112.98 ? 307 ARG B CA  1 
ATOM 4885 C C   . ARG B 2 307 ? 125.825 106.530 103.150 1.00 112.98 ? 307 ARG B C   1 
ATOM 4886 O O   . ARG B 2 307 ? 125.318 107.430 102.470 1.00 112.98 ? 307 ARG B O   1 
ATOM 4887 C CB  . ARG B 2 307 ? 128.307 106.125 102.971 1.00 112.98 ? 307 ARG B CB  1 
ATOM 4888 C CG  . ARG B 2 307 ? 128.290 106.447 101.483 1.00 112.98 ? 307 ARG B CG  1 
ATOM 4889 C CD  . ARG B 2 307 ? 128.074 105.198 100.643 1.00 112.98 ? 307 ARG B CD  1 
ATOM 4890 N NE  . ARG B 2 307 ? 129.286 104.392 100.553 1.00 112.98 ? 307 ARG B NE  1 
ATOM 4891 C CZ  . ARG B 2 307 ? 129.329 103.148 100.098 1.00 112.98 ? 307 ARG B CZ  1 
ATOM 4892 N NH1 . ARG B 2 307 ? 128.239 102.525 99.681  1.00 112.98 ? 307 ARG B NH1 1 
ATOM 4893 N NH2 . ARG B 2 307 ? 130.497 102.512 100.057 1.00 112.98 ? 307 ARG B NH2 1 
ATOM 4894 N N   . CYS B 2 308 ? 125.204 105.373 103.371 1.00 105.11 ? 308 CYS B N   1 
ATOM 4895 C CA  . CYS B 2 308 ? 123.885 105.084 102.820 1.00 105.11 ? 308 CYS B CA  1 
ATOM 4896 C C   . CYS B 2 308 ? 122.769 105.438 103.800 1.00 105.11 ? 308 CYS B C   1 
ATOM 4897 O O   . CYS B 2 308 ? 121.589 105.320 103.470 1.00 105.11 ? 308 CYS B O   1 
ATOM 4898 C CB  . CYS B 2 308 ? 123.785 103.619 102.402 1.00 105.11 ? 308 CYS B CB  1 
ATOM 4899 S SG  . CYS B 2 308 ? 124.874 103.146 101.044 1.00 105.11 ? 308 CYS B SG  1 
ATOM 4900 N N   . GLY B 2 309 ? 123.122 105.895 105.000 1.00 105.63 ? 309 GLY B N   1 
ATOM 4901 C CA  . GLY B 2 309 ? 122.121 106.281 105.979 1.00 105.63 ? 309 GLY B CA  1 
ATOM 4902 C C   . GLY B 2 309 ? 121.346 105.135 106.600 1.00 105.63 ? 309 GLY B C   1 
ATOM 4903 O O   . GLY B 2 309 ? 120.116 105.189 106.689 1.00 105.63 ? 309 GLY B O   1 
ATOM 4904 N N   . ILE B 2 310 ? 122.057 104.085 107.025 1.00 97.55  ? 310 ILE B N   1 
ATOM 4905 C CA  . ILE B 2 310 ? 121.422 102.890 107.578 1.00 97.55  ? 310 ILE B CA  1 
ATOM 4906 C C   . ILE B 2 310 ? 121.677 102.756 109.081 1.00 97.55  ? 310 ILE B C   1 
ATOM 4907 O O   . ILE B 2 310 ? 120.887 102.094 109.778 1.00 97.55  ? 310 ILE B O   1 
ATOM 4908 C CB  . ILE B 2 310 ? 121.935 101.672 106.770 1.00 97.55  ? 310 ILE B CB  1 
ATOM 4909 C CG1 . ILE B 2 310 ? 121.681 101.872 105.278 1.00 97.55  ? 310 ILE B CG1 1 
ATOM 4910 C CG2 . ILE B 2 310 ? 121.193 100.379 107.090 1.00 97.55  ? 310 ILE B CG2 1 
ATOM 4911 C CD1 . ILE B 2 310 ? 122.363 100.832 104.414 1.00 97.55  ? 310 ILE B CD1 1 
ATOM 4912 N N   . PHE B 2 311 ? 122.679 103.476 109.616 1.00 97.94  ? 311 PHE B N   1 
ATOM 4913 C CA  . PHE B 2 311 ? 123.380 103.086 110.845 1.00 97.94  ? 311 PHE B CA  1 
ATOM 4914 C C   . PHE B 2 311 ? 122.493 103.201 112.085 1.00 97.94  ? 311 PHE B C   1 
ATOM 4915 O O   . PHE B 2 311 ? 122.560 102.338 112.968 1.00 97.94  ? 311 PHE B O   1 
ATOM 4916 C CB  . PHE B 2 311 ? 124.655 103.946 110.964 1.00 97.94  ? 311 PHE B CB  1 
ATOM 4917 C CG  . PHE B 2 311 ? 125.709 103.435 111.947 1.00 97.94  ? 311 PHE B CG  1 
ATOM 4918 C CD1 . PHE B 2 311 ? 126.929 103.001 111.445 1.00 97.94  ? 311 PHE B CD1 1 
ATOM 4919 C CD2 . PHE B 2 311 ? 125.555 103.498 113.339 1.00 97.94  ? 311 PHE B CD2 1 
ATOM 4920 C CE1 . PHE B 2 311 ? 127.928 102.548 112.287 1.00 97.94  ? 311 PHE B CE1 1 
ATOM 4921 C CE2 . PHE B 2 311 ? 126.555 103.045 114.187 1.00 97.94  ? 311 PHE B CE2 1 
ATOM 4922 C CZ  . PHE B 2 311 ? 127.748 102.576 113.659 1.00 97.94  ? 311 PHE B CZ  1 
ATOM 4923 N N   . LEU B 2 312 ? 121.653 104.229 112.168 1.00 98.49  ? 312 LEU B N   1 
ATOM 4924 C CA  . LEU B 2 312 ? 120.815 104.390 113.353 1.00 98.49  ? 312 LEU B CA  1 
ATOM 4925 C C   . LEU B 2 312 ? 119.571 103.512 113.308 1.00 98.49  ? 312 LEU B C   1 
ATOM 4926 O O   . LEU B 2 312 ? 118.952 103.262 114.348 1.00 98.49  ? 312 LEU B O   1 
ATOM 4927 C CB  . LEU B 2 312 ? 120.420 105.856 113.557 1.00 98.49  ? 312 LEU B CB  1 
ATOM 4928 C CG  . LEU B 2 312 ? 121.335 106.782 114.376 1.00 98.49  ? 312 LEU B CG  1 
ATOM 4929 C CD1 . LEU B 2 312 ? 121.354 106.295 115.809 1.00 98.49  ? 312 LEU B CD1 1 
ATOM 4930 C CD2 . LEU B 2 312 ? 122.757 106.920 113.861 1.00 98.49  ? 312 LEU B CD2 1 
ATOM 4931 N N   . ILE B 2 313 ? 119.185 103.058 112.118 1.00 91.87  ? 313 ILE B N   1 
ATOM 4932 C CA  . ILE B 2 313 ? 118.101 102.090 111.986 1.00 91.87  ? 313 ILE B CA  1 
ATOM 4933 C C   . ILE B 2 313 ? 118.601 100.750 112.512 1.00 91.87  ? 313 ILE B C   1 
ATOM 4934 O O   . ILE B 2 313 ? 117.877 100.032 113.212 1.00 91.87  ? 313 ILE B O   1 
ATOM 4935 C CB  . ILE B 2 313 ? 117.608 101.990 110.529 1.00 91.87  ? 313 ILE B CB  1 
ATOM 4936 C CG1 . ILE B 2 313 ? 117.103 103.350 110.044 1.00 91.87  ? 313 ILE B CG1 1 
ATOM 4937 C CG2 . ILE B 2 313 ? 116.495 100.960 110.394 1.00 91.87  ? 313 ILE B CG2 1 
ATOM 4938 C CD1 . ILE B 2 313 ? 118.023 104.031 109.059 1.00 91.87  ? 313 ILE B CD1 1 
ATOM 4939 N N   . LEU B 2 314 ? 119.867 100.432 112.218 1.00 90.64  ? 314 LEU B N   1 
ATOM 4940 C CA  . LEU B 2 314 ? 120.464 99.156  112.600 1.00 90.64  ? 314 LEU B CA  1 
ATOM 4941 C C   . LEU B 2 314 ? 120.668 99.007  114.104 1.00 90.64  ? 314 LEU B C   1 
ATOM 4942 O O   . LEU B 2 314 ? 120.798 97.874  114.579 1.00 90.64  ? 314 LEU B O   1 
ATOM 4943 C CB  . LEU B 2 314 ? 121.807 98.970  111.892 1.00 90.64  ? 314 LEU B CB  1 
ATOM 4944 C CG  . LEU B 2 314 ? 121.782 98.608  110.406 1.00 90.64  ? 314 LEU B CG  1 
ATOM 4945 C CD1 . LEU B 2 314 ? 123.185 98.672  109.827 1.00 90.64  ? 314 LEU B CD1 1 
ATOM 4946 C CD2 . LEU B 2 314 ? 121.164 97.245  110.170 1.00 90.64  ? 314 LEU B CD2 1 
ATOM 4947 N N   . GLU B 2 315 ? 120.699 100.107 114.860 1.00 93.09  ? 315 GLU B N   1 
ATOM 4948 C CA  . GLU B 2 315 ? 120.807 100.036 116.312 1.00 93.09  ? 315 GLU B CA  1 
ATOM 4949 C C   . GLU B 2 315 ? 119.521 99.524  116.960 1.00 93.09  ? 315 GLU B C   1 
ATOM 4950 O O   . GLU B 2 315 ? 119.578 98.916  118.036 1.00 93.09  ? 315 GLU B O   1 
ATOM 4951 C CB  . GLU B 2 315 ? 121.193 101.422 116.859 1.00 93.09  ? 315 GLU B CB  1 
ATOM 4952 C CG  . GLU B 2 315 ? 121.470 101.509 118.363 1.00 93.09  ? 315 GLU B CG  1 
ATOM 4953 C CD  . GLU B 2 315 ? 121.894 102.892 118.808 1.00 93.09  ? 315 GLU B CD  1 
ATOM 4954 O OE1 . GLU B 2 315 ? 121.955 103.798 117.954 1.00 93.09  ? 315 GLU B OE1 1 
ATOM 4955 O OE2 . GLU B 2 315 ? 122.165 103.074 120.014 1.00 93.09  ? 315 GLU B OE2 1 
ATOM 4956 N N   . LYS B 2 316 ? 118.376 99.668  116.284 1.00 90.26  ? 316 LYS B N   1 
ATOM 4957 C CA  . LYS B 2 316 ? 117.072 99.271  116.807 1.00 90.26  ? 316 LYS B CA  1 
ATOM 4958 C C   . LYS B 2 316 ? 116.897 97.747  116.850 1.00 90.26  ? 316 LYS B C   1 
ATOM 4959 O O   . LYS B 2 316 ? 115.990 97.250  117.529 1.00 90.26  ? 316 LYS B O   1 
ATOM 4960 C CB  . LYS B 2 316 ? 115.988 99.974  115.963 1.00 90.26  ? 316 LYS B CB  1 
ATOM 4961 C CG  . LYS B 2 316 ? 114.529 99.879  116.423 1.00 90.26  ? 316 LYS B CG  1 
ATOM 4962 C CD  . LYS B 2 316 ? 113.614 100.708 115.539 1.00 90.26  ? 316 LYS B CD  1 
ATOM 4963 C CE  . LYS B 2 316 ? 112.170 100.615 116.001 1.00 90.26  ? 316 LYS B CE  1 
ATOM 4964 N NZ  . LYS B 2 316 ? 111.261 101.429 115.149 1.00 90.26  ? 316 LYS B NZ  1 
ATOM 4965 N N   . LEU B 2 317 ? 117.810 96.984  116.238 1.00 87.96  ? 317 LEU B N   1 
ATOM 4966 C CA  . LEU B 2 317 ? 117.876 95.528  116.360 1.00 87.96  ? 317 LEU B CA  1 
ATOM 4967 C C   . LEU B 2 317 ? 118.442 95.046  117.700 1.00 87.96  ? 317 LEU B C   1 
ATOM 4968 O O   . LEU B 2 317 ? 118.640 93.835  117.854 1.00 87.96  ? 317 LEU B O   1 
ATOM 4969 C CB  . LEU B 2 317 ? 118.724 94.943  115.230 1.00 87.96  ? 317 LEU B CB  1 
ATOM 4970 C CG  . LEU B 2 317 ? 118.238 95.160  113.802 1.00 87.96  ? 317 LEU B CG  1 
ATOM 4971 C CD1 . LEU B 2 317 ? 119.419 95.289  112.865 1.00 87.96  ? 317 LEU B CD1 1 
ATOM 4972 C CD2 . LEU B 2 317 ? 117.348 94.017  113.381 1.00 87.96  ? 317 LEU B CD2 1 
ATOM 4973 N N   . LYS B 2 318 ? 118.717 95.958  118.644 1.00 90.10  ? 318 LYS B N   1 
ATOM 4974 C CA  . LYS B 2 318 ? 119.150 95.588  119.990 1.00 90.10  ? 318 LYS B CA  1 
ATOM 4975 C C   . LYS B 2 318 ? 118.077 94.767  120.704 1.00 90.10  ? 318 LYS B C   1 
ATOM 4976 O O   . LYS B 2 318 ? 118.398 93.829  121.444 1.00 90.10  ? 318 LYS B O   1 
ATOM 4977 C CB  . LYS B 2 318 ? 119.506 96.865  120.766 1.00 90.10  ? 318 LYS B CB  1 
ATOM 4978 C CG  . LYS B 2 318 ? 119.310 96.876  122.290 1.00 90.10  ? 318 LYS B CG  1 
ATOM 4979 C CD  . LYS B 2 318 ? 120.338 96.026  123.042 1.00 90.10  ? 318 LYS B CD  1 
ATOM 4980 C CE  . LYS B 2 318 ? 120.073 96.044  124.539 1.00 90.10  ? 318 LYS B CE  1 
ATOM 4981 N NZ  . LYS B 2 318 ? 121.228 95.508  125.308 1.00 90.10  ? 318 LYS B NZ  1 
ATOM 4982 N N   . ILE B 2 319 ? 116.802 95.070  120.434 1.00 90.77  ? 319 ILE B N   1 
ATOM 4983 C CA  . ILE B 2 319 ? 115.681 94.345  121.030 1.00 90.77  ? 319 ILE B CA  1 
ATOM 4984 C C   . ILE B 2 319 ? 115.642 92.896  120.539 1.00 90.77  ? 319 ILE B C   1 
ATOM 4985 O O   . ILE B 2 319 ? 115.533 91.956  121.339 1.00 90.77  ? 319 ILE B O   1 
ATOM 4986 C CB  . ILE B 2 319 ? 114.369 95.101  120.735 1.00 90.77  ? 319 ILE B CB  1 
ATOM 4987 C CG1 . ILE B 2 319 ? 114.200 96.259  121.720 1.00 90.77  ? 319 ILE B CG1 1 
ATOM 4988 C CG2 . ILE B 2 319 ? 113.149 94.191  120.797 1.00 90.77  ? 319 ILE B CG2 1 
ATOM 4989 C CD1 . ILE B 2 319 ? 113.065 97.196  121.379 1.00 90.77  ? 319 ILE B CD1 1 
ATOM 4990 N N   . ILE B 2 320 ? 115.806 92.685  119.229 1.00 92.77  ? 320 ILE B N   1 
ATOM 4991 C CA  . ILE B 2 320 ? 115.698 91.324  118.707 1.00 92.77  ? 320 ILE B CA  1 
ATOM 4992 C C   . ILE B 2 320 ? 116.986 90.535  118.968 1.00 92.77  ? 320 ILE B C   1 
ATOM 4993 O O   . ILE B 2 320 ? 116.939 89.311  119.157 1.00 92.77  ? 320 ILE B O   1 
ATOM 4994 C CB  . ILE B 2 320 ? 115.284 91.355  117.215 1.00 92.77  ? 320 ILE B CB  1 
ATOM 4995 C CG1 . ILE B 2 320 ? 114.907 89.963  116.697 1.00 92.77  ? 320 ILE B CG1 1 
ATOM 4996 C CG2 . ILE B 2 320 ? 116.355 91.961  116.336 1.00 92.77  ? 320 ILE B CG2 1 
ATOM 4997 C CD1 . ILE B 2 320 ? 114.198 89.982  115.363 1.00 92.77  ? 320 ILE B CD1 1 
ATOM 4998 N N   . THR B 2 321 ? 118.140 91.209  119.077 1.00 91.74  ? 321 THR B N   1 
ATOM 4999 C CA  . THR B 2 321 ? 119.349 90.485  119.465 1.00 91.74  ? 321 THR B CA  1 
ATOM 5000 C C   . THR B 2 321 ? 119.344 90.148  120.951 1.00 91.74  ? 321 THR B C   1 
ATOM 5001 O O   . THR B 2 321 ? 119.887 89.114  121.352 1.00 91.74  ? 321 THR B O   1 
ATOM 5002 C CB  . THR B 2 321 ? 120.606 91.270  119.095 1.00 91.74  ? 321 THR B CB  1 
ATOM 5003 O OG1 . THR B 2 321 ? 120.542 92.586  119.653 1.00 91.74  ? 321 THR B OG1 1 
ATOM 5004 C CG2 . THR B 2 321 ? 120.783 91.333  117.585 1.00 91.74  ? 321 THR B CG2 1 
ATOM 5005 N N   . TYR B 2 322 ? 118.695 90.972  121.782 1.00 96.32  ? 322 TYR B N   1 
ATOM 5006 C CA  . TYR B 2 322 ? 118.534 90.599  123.183 1.00 96.32  ? 322 TYR B CA  1 
ATOM 5007 C C   . TYR B 2 322 ? 117.509 89.480  123.335 1.00 96.32  ? 322 TYR B C   1 
ATOM 5008 O O   . TYR B 2 322 ? 117.612 88.659  124.251 1.00 96.32  ? 322 TYR B O   1 
ATOM 5009 C CB  . TYR B 2 322 ? 118.142 91.814  124.028 1.00 96.32  ? 322 TYR B CB  1 
ATOM 5010 C CG  . TYR B 2 322 ? 118.026 91.485  125.502 1.00 96.32  ? 322 TYR B CG  1 
ATOM 5011 C CD1 . TYR B 2 322 ? 119.160 91.244  126.272 1.00 96.32  ? 322 TYR B CD1 1 
ATOM 5012 C CD2 . TYR B 2 322 ? 116.781 91.371  126.113 1.00 96.32  ? 322 TYR B CD2 1 
ATOM 5013 C CE1 . TYR B 2 322 ? 119.057 90.921  127.617 1.00 96.32  ? 322 TYR B CE1 1 
ATOM 5014 C CE2 . TYR B 2 322 ? 116.667 91.047  127.456 1.00 96.32  ? 322 TYR B CE2 1 
ATOM 5015 C CZ  . TYR B 2 322 ? 117.809 90.824  128.200 1.00 96.32  ? 322 TYR B CZ  1 
ATOM 5016 O OH  . TYR B 2 322 ? 117.706 90.504  129.534 1.00 96.32  ? 322 TYR B OH  1 
ATOM 5017 N N   . ARG B 2 323 ? 116.520 89.421  122.437 1.00 93.49  ? 323 ARG B N   1 
ATOM 5018 C CA  . ARG B 2 323 ? 115.567 88.313  122.464 1.00 93.49  ? 323 ARG B CA  1 
ATOM 5019 C C   . ARG B 2 323 ? 116.248 87.022  122.003 1.00 93.49  ? 323 ARG B C   1 
ATOM 5020 O O   . ARG B 2 323 ? 115.955 85.939  122.526 1.00 93.49  ? 323 ARG B O   1 
ATOM 5021 C CB  . ARG B 2 323 ? 114.337 88.703  121.612 1.00 93.49  ? 323 ARG B CB  1 
ATOM 5022 C CG  . ARG B 2 323 ? 113.034 87.809  121.495 1.00 93.49  ? 323 ARG B CG  1 
ATOM 5023 C CD  . ARG B 2 323 ? 113.091 86.370  120.959 1.00 93.49  ? 323 ARG B CD  1 
ATOM 5024 N NE  . ARG B 2 323 ? 113.618 86.294  119.602 1.00 93.49  ? 323 ARG B NE  1 
ATOM 5025 C CZ  . ARG B 2 323 ? 112.923 86.555  118.504 1.00 93.49  ? 323 ARG B CZ  1 
ATOM 5026 N NH1 . ARG B 2 323 ? 111.635 86.854  118.554 1.00 93.49  ? 323 ARG B NH1 1 
ATOM 5027 N NH2 . ARG B 2 323 ? 113.531 86.493  117.323 1.00 93.49  ? 323 ARG B NH2 1 
ATOM 5028 N N   . ASN B 2 324 ? 117.166 87.111  121.041 1.00 93.75  ? 324 ASN B N   1 
ATOM 5029 C CA  . ASN B 2 324 ? 117.922 85.921  120.665 1.00 93.75  ? 324 ASN B CA  1 
ATOM 5030 C C   . ASN B 2 324 ? 118.929 85.534  121.745 1.00 93.75  ? 324 ASN B C   1 
ATOM 5031 O O   . ASN B 2 324 ? 119.192 84.347  121.945 1.00 93.75  ? 324 ASN B O   1 
ATOM 5032 C CB  . ASN B 2 324 ? 118.602 86.124  119.313 1.00 93.75  ? 324 ASN B CB  1 
ATOM 5033 C CG  . ASN B 2 324 ? 117.757 85.607  118.165 1.00 93.75  ? 324 ASN B CG  1 
ATOM 5034 O OD1 . ASN B 2 324 ? 116.666 85.079  118.379 1.00 93.75  ? 324 ASN B OD1 1 
ATOM 5035 N ND2 . ASN B 2 324 ? 118.259 85.739  116.946 1.00 93.75  ? 324 ASN B ND2 1 
ATOM 5036 N N   . LEU B 2 325 ? 119.476 86.509  122.473 1.00 91.75  ? 325 LEU B N   1 
ATOM 5037 C CA  . LEU B 2 325 ? 120.291 86.212  123.647 1.00 91.75  ? 325 LEU B CA  1 
ATOM 5038 C C   . LEU B 2 325 ? 119.486 85.557  124.767 1.00 91.75  ? 325 LEU B C   1 
ATOM 5039 O O   . LEU B 2 325 ? 120.010 84.649  125.417 1.00 91.75  ? 325 LEU B O   1 
ATOM 5040 C CB  . LEU B 2 325 ? 120.976 87.494  124.136 1.00 91.75  ? 325 LEU B CB  1 
ATOM 5041 C CG  . LEU B 2 325 ? 122.122 87.380  125.148 1.00 91.75  ? 325 LEU B CG  1 
ATOM 5042 C CD1 . LEU B 2 325 ? 123.218 88.357  124.777 1.00 91.75  ? 325 LEU B CD1 1 
ATOM 5043 C CD2 . LEU B 2 325 ? 121.660 87.666  126.570 1.00 91.75  ? 325 LEU B CD2 1 
ATOM 5044 N N   . PHE B 2 326 ? 118.242 85.985  124.986 1.00 105.68 ? 326 PHE B N   1 
ATOM 5045 C CA  . PHE B 2 326 ? 117.249 85.305  125.811 1.00 105.68 ? 326 PHE B CA  1 
ATOM 5046 C C   . PHE B 2 326 ? 116.998 83.868  125.377 1.00 105.68 ? 326 PHE B C   1 
ATOM 5047 O O   . PHE B 2 326 ? 116.834 82.994  126.233 1.00 105.68 ? 326 PHE B O   1 
ATOM 5048 C CB  . PHE B 2 326 ? 115.926 86.085  125.778 1.00 105.68 ? 326 PHE B CB  1 
ATOM 5049 C CG  . PHE B 2 326 ? 114.834 85.488  126.620 1.00 105.68 ? 326 PHE B CG  1 
ATOM 5050 C CD1 . PHE B 2 326 ? 114.845 85.623  127.997 1.00 105.68 ? 326 PHE B CD1 1 
ATOM 5051 C CD2 . PHE B 2 326 ? 113.782 84.798  126.023 1.00 105.68 ? 326 PHE B CD2 1 
ATOM 5052 C CE1 . PHE B 2 326 ? 113.838 85.073  128.772 1.00 105.68 ? 326 PHE B CE1 1 
ATOM 5053 C CE2 . PHE B 2 326 ? 112.773 84.243  126.787 1.00 105.68 ? 326 PHE B CE2 1 
ATOM 5054 C CZ  . PHE B 2 326 ? 112.799 84.383  128.165 1.00 105.68 ? 326 PHE B CZ  1 
ATOM 5055 N N   . LYS B 2 327 ? 116.944 83.622  124.062 1.00 105.75 ? 327 LYS B N   1 
ATOM 5056 C CA  . LYS B 2 327 ? 116.869 82.252  123.551 1.00 105.75 ? 327 LYS B CA  1 
ATOM 5057 C C   . LYS B 2 327 ? 118.109 81.440  123.927 1.00 105.75 ? 327 LYS B C   1 
ATOM 5058 O O   . LYS B 2 327 ? 117.994 80.286  124.358 1.00 105.75 ? 327 LYS B O   1 
ATOM 5059 C CB  . LYS B 2 327 ? 116.685 82.264  122.029 1.00 105.75 ? 327 LYS B CB  1 
ATOM 5060 C CG  . LYS B 2 327 ? 116.629 80.884  121.379 1.00 105.75 ? 327 LYS B CG  1 
ATOM 5061 C CD  . LYS B 2 327 ? 116.397 80.948  119.869 1.00 105.75 ? 327 LYS B CD  1 
ATOM 5062 C CE  . LYS B 2 327 ? 115.028 81.490  119.524 1.00 105.75 ? 327 LYS B CE  1 
ATOM 5063 N NZ  . LYS B 2 327 ? 115.004 82.260  118.259 1.00 105.75 ? 327 LYS B NZ  1 
ATOM 5064 N N   . LYS B 2 328 ? 119.298 82.038  123.798 1.00 104.93 ? 328 LYS B N   1 
ATOM 5065 C CA  . LYS B 2 328 ? 120.531 81.321  124.137 1.00 104.93 ? 328 LYS B CA  1 
ATOM 5066 C C   . LYS B 2 328 ? 120.655 81.079  125.640 1.00 104.93 ? 328 LYS B C   1 
ATOM 5067 O O   . LYS B 2 328 ? 121.287 80.109  126.063 1.00 104.93 ? 328 LYS B O   1 
ATOM 5068 C CB  . LYS B 2 328 ? 121.768 82.059  123.614 1.00 104.93 ? 328 LYS B CB  1 
ATOM 5069 C CG  . LYS B 2 328 ? 121.741 82.384  122.134 1.00 104.93 ? 328 LYS B CG  1 
ATOM 5070 C CD  . LYS B 2 328 ? 121.770 81.139  121.275 1.00 104.93 ? 328 LYS B CD  1 
ATOM 5071 C CE  . LYS B 2 328 ? 123.075 80.398  121.435 1.00 104.93 ? 328 LYS B CE  1 
ATOM 5072 N NZ  . LYS B 2 328 ? 124.255 81.303  121.326 1.00 104.93 ? 328 LYS B NZ  1 
ATOM 5073 N N   . VAL B 2 329 ? 120.074 81.956  126.464 1.00 107.46 ? 329 VAL B N   1 
ATOM 5074 C CA  . VAL B 2 329 ? 120.033 81.685  127.902 1.00 107.46 ? 329 VAL B CA  1 
ATOM 5075 C C   . VAL B 2 329 ? 119.005 80.598  128.230 1.00 107.46 ? 329 VAL B C   1 
ATOM 5076 O O   . VAL B 2 329 ? 119.275 79.712  129.055 1.00 107.46 ? 329 VAL B O   1 
ATOM 5077 C CB  . VAL B 2 329 ? 119.784 82.995  128.682 1.00 107.46 ? 329 VAL B CB  1 
ATOM 5078 C CG1 . VAL B 2 329 ? 119.609 82.748  130.177 1.00 107.46 ? 329 VAL B CG1 1 
ATOM 5079 C CG2 . VAL B 2 329 ? 120.953 83.939  128.491 1.00 107.46 ? 329 VAL B CG2 1 
ATOM 5080 N N   . TYR B 2 330 ? 117.834 80.626  127.575 1.00 109.24 ? 330 TYR B N   1 
ATOM 5081 C CA  . TYR B 2 330 ? 116.749 79.695  127.894 1.00 109.24 ? 330 TYR B CA  1 
ATOM 5082 C C   . TYR B 2 330 ? 117.098 78.268  127.482 1.00 109.24 ? 330 TYR B C   1 
ATOM 5083 O O   . TYR B 2 330 ? 116.777 77.315  128.202 1.00 109.24 ? 330 TYR B O   1 
ATOM 5084 C CB  . TYR B 2 330 ? 115.445 80.212  127.245 1.00 109.24 ? 330 TYR B CB  1 
ATOM 5085 C CG  . TYR B 2 330 ? 114.154 79.370  127.304 1.00 109.24 ? 330 TYR B CG  1 
ATOM 5086 C CD1 . TYR B 2 330 ? 113.955 78.230  126.507 1.00 109.24 ? 330 TYR B CD1 1 
ATOM 5087 C CD2 . TYR B 2 330 ? 113.136 79.723  128.185 1.00 109.24 ? 330 TYR B CD2 1 
ATOM 5088 C CE1 . TYR B 2 330 ? 112.791 77.490  126.585 1.00 109.24 ? 330 TYR B CE1 1 
ATOM 5089 C CE2 . TYR B 2 330 ? 111.966 78.983  128.268 1.00 109.24 ? 330 TYR B CE2 1 
ATOM 5090 C CZ  . TYR B 2 330 ? 111.802 77.871  127.465 1.00 109.24 ? 330 TYR B CZ  1 
ATOM 5091 O OH  . TYR B 2 330 ? 110.643 77.135  127.544 1.00 109.24 ? 330 TYR B OH  1 
ATOM 5092 N N   . LEU B 2 331 ? 117.750 78.094  126.334 1.00 116.14 ? 331 LEU B N   1 
ATOM 5093 C CA  . LEU B 2 331 ? 118.110 76.742  125.915 1.00 116.14 ? 331 LEU B CA  1 
ATOM 5094 C C   . LEU B 2 331 ? 119.331 76.210  126.661 1.00 116.14 ? 331 LEU B C   1 
ATOM 5095 O O   . LEU B 2 331 ? 119.587 75.001  126.649 1.00 116.14 ? 331 LEU B O   1 
ATOM 5096 C CB  . LEU B 2 331 ? 118.321 76.689  124.401 1.00 116.14 ? 331 LEU B CB  1 
ATOM 5097 C CG  . LEU B 2 331 ? 117.142 76.604  123.415 1.00 116.14 ? 331 LEU B CG  1 
ATOM 5098 C CD1 . LEU B 2 331 ? 116.143 77.759  123.374 1.00 116.14 ? 331 LEU B CD1 1 
ATOM 5099 C CD2 . LEU B 2 331 ? 117.763 76.428  122.047 1.00 116.14 ? 331 LEU B CD2 1 
ATOM 5100 N N   . LEU B 2 332 ? 120.091 77.079  127.323 1.00 113.50 ? 332 LEU B N   1 
ATOM 5101 C CA  . LEU B 2 332 ? 121.297 76.626  128.005 1.00 113.50 ? 332 LEU B CA  1 
ATOM 5102 C C   . LEU B 2 332 ? 121.046 76.164  129.433 1.00 113.50 ? 332 LEU B C   1 
ATOM 5103 O O   . LEU B 2 332 ? 121.919 75.509  130.013 1.00 113.50 ? 332 LEU B O   1 
ATOM 5104 C CB  . LEU B 2 332 ? 122.349 77.733  128.021 1.00 113.50 ? 332 LEU B CB  1 
ATOM 5105 C CG  . LEU B 2 332 ? 123.399 77.590  126.920 1.00 113.50 ? 332 LEU B CG  1 
ATOM 5106 C CD1 . LEU B 2 332 ? 124.330 78.803  126.873 1.00 113.50 ? 332 LEU B CD1 1 
ATOM 5107 C CD2 . LEU B 2 332 ? 124.164 76.282  127.043 1.00 113.50 ? 332 LEU B CD2 1 
ATOM 5108 N N   . LEU B 2 333 ? 119.896 76.486  130.019 1.00 112.83 ? 333 LEU B N   1 
ATOM 5109 C CA  . LEU B 2 333 ? 119.696 76.203  131.436 1.00 112.83 ? 333 LEU B CA  1 
ATOM 5110 C C   . LEU B 2 333 ? 118.412 75.434  131.734 1.00 112.83 ? 333 LEU B C   1 
ATOM 5111 O O   . LEU B 2 333 ? 118.361 74.768  132.774 1.00 112.83 ? 333 LEU B O   1 
ATOM 5112 C CB  . LEU B 2 333 ? 119.738 77.525  132.233 1.00 112.83 ? 333 LEU B CB  1 
ATOM 5113 C CG  . LEU B 2 333 ? 119.773 77.668  133.762 1.00 112.83 ? 333 LEU B CG  1 
ATOM 5114 C CD1 . LEU B 2 333 ? 120.514 78.951  134.103 1.00 112.83 ? 333 LEU B CD1 1 
ATOM 5115 C CD2 . LEU B 2 333 ? 118.411 77.719  134.404 1.00 112.83 ? 333 LEU B CD2 1 
ATOM 5116 N N   . LYS B 2 334 ? 117.390 75.509  130.865 1.00 117.41 ? 334 LYS B N   1 
ATOM 5117 C CA  . LYS B 2 334 ? 116.285 74.539  130.758 1.00 117.41 ? 334 LYS B CA  1 
ATOM 5118 C C   . LYS B 2 334 ? 115.409 74.467  132.015 1.00 117.41 ? 334 LYS B C   1 
ATOM 5119 O O   . LYS B 2 334 ? 115.336 73.440  132.693 1.00 117.41 ? 334 LYS B O   1 
ATOM 5120 C CB  . LYS B 2 334 ? 116.821 73.152  130.383 1.00 117.41 ? 334 LYS B CB  1 
ATOM 5121 C CG  . LYS B 2 334 ? 115.821 72.259  129.649 1.00 117.41 ? 334 LYS B CG  1 
ATOM 5122 C CD  . LYS B 2 334 ? 116.196 70.779  129.727 1.00 117.41 ? 334 LYS B CD  1 
ATOM 5123 C CE  . LYS B 2 334 ? 117.660 70.526  129.380 1.00 117.41 ? 334 LYS B CE  1 
ATOM 5124 N NZ  . LYS B 2 334 ? 117.990 70.957  127.994 1.00 117.41 ? 334 LYS B NZ  1 
ATOM 5125 N N   . THR B 2 335 ? 114.744 75.578  132.329 1.00 111.56 ? 335 THR B N   1 
ATOM 5126 C CA  . THR B 2 335 ? 113.710 75.599  133.357 1.00 111.56 ? 335 THR B CA  1 
ATOM 5127 C C   . THR B 2 335 ? 112.669 76.650  132.994 1.00 111.56 ? 335 THR B C   1 
ATOM 5128 O O   . THR B 2 335 ? 112.808 77.379  132.008 1.00 111.56 ? 335 THR B O   1 
ATOM 5129 C CB  . THR B 2 335 ? 114.289 75.866  134.753 1.00 111.56 ? 335 THR B CB  1 
ATOM 5130 O OG1 . THR B 2 335 ? 113.285 75.615  135.744 1.00 111.56 ? 335 THR B OG1 1 
ATOM 5131 C CG2 . THR B 2 335 ? 114.760 77.295  134.869 1.00 111.56 ? 335 THR B CG2 1 
ATOM 5132 N N   . HIS B 2 336 ? 111.605 76.716  133.799 1.00 113.58 ? 336 HIS B N   1 
ATOM 5133 C CA  . HIS B 2 336 ? 110.526 77.657  133.519 1.00 113.58 ? 336 HIS B CA  1 
ATOM 5134 C C   . HIS B 2 336 ? 110.747 79.001  134.207 1.00 113.58 ? 336 HIS B C   1 
ATOM 5135 O O   . HIS B 2 336 ? 110.345 80.044  133.680 1.00 113.58 ? 336 HIS B O   1 
ATOM 5136 C CB  . HIS B 2 336 ? 109.185 77.052  133.935 1.00 113.58 ? 336 HIS B CB  1 
ATOM 5137 C CG  . HIS B 2 336 ? 108.774 75.875  133.108 1.00 113.58 ? 336 HIS B CG  1 
ATOM 5138 N ND1 . HIS B 2 336 ? 108.474 75.977  131.766 1.00 113.58 ? 336 HIS B ND1 1 
ATOM 5139 C CD2 . HIS B 2 336 ? 108.615 74.569  133.430 1.00 113.58 ? 336 HIS B CD2 1 
ATOM 5140 C CE1 . HIS B 2 336 ? 108.149 74.785  131.298 1.00 113.58 ? 336 HIS B CE1 1 
ATOM 5141 N NE2 . HIS B 2 336 ? 108.226 73.914  132.287 1.00 113.58 ? 336 HIS B NE2 1 
ATOM 5142 N N   . GLN B 2 337 ? 111.379 79.005  135.382 1.00 104.37 ? 337 GLN B N   1 
ATOM 5143 C CA  . GLN B 2 337 ? 111.608 80.242  136.136 1.00 104.37 ? 337 GLN B CA  1 
ATOM 5144 C C   . GLN B 2 337 ? 113.110 80.526  136.213 1.00 104.37 ? 337 GLN B C   1 
ATOM 5145 O O   . GLN B 2 337 ? 113.879 79.799  136.842 1.00 104.37 ? 337 GLN B O   1 
ATOM 5146 C CB  . GLN B 2 337 ? 110.936 80.181  137.511 1.00 104.37 ? 337 GLN B CB  1 
ATOM 5147 C CG  . GLN B 2 337 ? 111.155 78.921  138.356 1.00 104.37 ? 337 GLN B CG  1 
ATOM 5148 C CD  . GLN B 2 337 ? 110.092 77.864  138.128 1.00 104.37 ? 337 GLN B CD  1 
ATOM 5149 O OE1 . GLN B 2 337 ? 109.328 77.933  137.167 1.00 104.37 ? 337 GLN B OE1 1 
ATOM 5150 N NE2 . GLN B 2 337 ? 110.036 76.880  139.018 1.00 104.37 ? 337 GLN B NE2 1 
ATOM 5151 N N   . LEU B 2 338 ? 113.527 81.608  135.559 1.00 100.89 ? 338 LEU B N   1 
ATOM 5152 C CA  . LEU B 2 338 ? 114.941 81.945  135.467 1.00 100.89 ? 338 LEU B CA  1 
ATOM 5153 C C   . LEU B 2 338 ? 115.248 83.206  136.265 1.00 100.89 ? 338 LEU B C   1 
ATOM 5154 O O   . LEU B 2 338 ? 114.476 84.168  136.253 1.00 100.89 ? 338 LEU B O   1 
ATOM 5155 C CB  . LEU B 2 338 ? 115.357 82.148  134.007 1.00 100.89 ? 338 LEU B CB  1 
ATOM 5156 C CG  . LEU B 2 338 ? 115.638 80.940  133.105 1.00 100.89 ? 338 LEU B CG  1 
ATOM 5157 C CD1 . LEU B 2 338 ? 114.364 80.313  132.552 1.00 100.89 ? 338 LEU B CD1 1 
ATOM 5158 C CD2 . LEU B 2 338 ? 116.572 81.327  131.971 1.00 100.89 ? 338 LEU B CD2 1 
ATOM 5159 N N   . SER B 2 339 ? 116.388 83.202  136.948 1.00 101.89 ? 339 SER B N   1 
ATOM 5160 C CA  . SER B 2 339 ? 116.808 84.336  137.757 1.00 101.89 ? 339 SER B CA  1 
ATOM 5161 C C   . SER B 2 339 ? 117.507 85.384  136.894 1.00 101.89 ? 339 SER B C   1 
ATOM 5162 O O   . SER B 2 339 ? 118.168 85.069  135.903 1.00 101.89 ? 339 SER B O   1 
ATOM 5163 C CB  . SER B 2 339 ? 117.734 83.881  138.886 1.00 101.89 ? 339 SER B CB  1 
ATOM 5164 O OG  . SER B 2 339 ? 119.068 83.755  138.429 1.00 101.89 ? 339 SER B OG  1 
ATOM 5165 N N   . LEU B 2 340 ? 117.372 86.648  137.309 1.00 100.18 ? 340 LEU B N   1 
ATOM 5166 C CA  . LEU B 2 340 ? 117.808 87.767  136.476 1.00 100.18 ? 340 LEU B CA  1 
ATOM 5167 C C   . LEU B 2 340 ? 119.319 87.978  136.521 1.00 100.18 ? 340 LEU B C   1 
ATOM 5168 O O   . LEU B 2 340 ? 119.859 88.738  135.705 1.00 100.18 ? 340 LEU B O   1 
ATOM 5169 C CB  . LEU B 2 340 ? 117.085 89.042  136.909 1.00 100.18 ? 340 LEU B CB  1 
ATOM 5170 C CG  . LEU B 2 340 ? 115.574 89.072  136.673 1.00 100.18 ? 340 LEU B CG  1 
ATOM 5171 C CD1 . LEU B 2 340 ? 114.870 89.813  137.795 1.00 100.18 ? 340 LEU B CD1 1 
ATOM 5172 C CD2 . LEU B 2 340 ? 115.258 89.709  135.331 1.00 100.18 ? 340 LEU B CD2 1 
ATOM 5173 N N   . ASP B 2 341 ? 120.011 87.321  137.457 1.00 110.95 ? 341 ASP B N   1 
ATOM 5174 C CA  . ASP B 2 341 ? 121.450 87.523  137.611 1.00 110.95 ? 341 ASP B CA  1 
ATOM 5175 C C   . ASP B 2 341 ? 122.230 86.902  136.456 1.00 110.95 ? 341 ASP B C   1 
ATOM 5176 O O   . ASP B 2 341 ? 123.295 87.405  136.076 1.00 110.95 ? 341 ASP B O   1 
ATOM 5177 C CB  . ASP B 2 341 ? 121.911 86.945  138.948 1.00 110.95 ? 341 ASP B CB  1 
ATOM 5178 C CG  . ASP B 2 341 ? 121.321 87.682  140.135 1.00 110.95 ? 341 ASP B CG  1 
ATOM 5179 O OD1 . ASP B 2 341 ? 121.025 88.888  139.999 1.00 110.95 ? 341 ASP B OD1 1 
ATOM 5180 O OD2 . ASP B 2 341 ? 121.147 87.056  141.201 1.00 110.95 ? 341 ASP B OD2 1 
ATOM 5181 N N   . ALA B 2 342 ? 121.707 85.815  135.878 1.00 110.07 ? 342 ALA B N   1 
ATOM 5182 C CA  . ALA B 2 342 ? 122.333 85.207  134.708 1.00 110.07 ? 342 ALA B CA  1 
ATOM 5183 C C   . ALA B 2 342 ? 122.245 86.109  133.482 1.00 110.07 ? 342 ALA B C   1 
ATOM 5184 O O   . ALA B 2 342 ? 123.224 86.231  132.734 1.00 110.07 ? 342 ALA B O   1 
ATOM 5185 C CB  . ALA B 2 342 ? 121.693 83.851  134.416 1.00 110.07 ? 342 ALA B CB  1 
ATOM 5186 N N   . PHE B 2 343 ? 121.096 86.764  133.277 1.00 104.04 ? 343 PHE B N   1 
ATOM 5187 C CA  . PHE B 2 343 ? 120.979 87.736  132.192 1.00 104.04 ? 343 PHE B CA  1 
ATOM 5188 C C   . PHE B 2 343 ? 121.825 88.971  132.471 1.00 104.04 ? 343 PHE B C   1 
ATOM 5189 O O   . PHE B 2 343 ? 122.333 89.602  131.534 1.00 104.04 ? 343 PHE B O   1 
ATOM 5190 C CB  . PHE B 2 343 ? 119.520 88.153  131.945 1.00 104.04 ? 343 PHE B CB  1 
ATOM 5191 C CG  . PHE B 2 343 ? 118.528 87.013  131.880 1.00 104.04 ? 343 PHE B CG  1 
ATOM 5192 C CD1 . PHE B 2 343 ? 118.113 86.532  130.648 1.00 104.04 ? 343 PHE B CD1 1 
ATOM 5193 C CD2 . PHE B 2 343 ? 117.901 86.528  133.025 1.00 104.04 ? 343 PHE B CD2 1 
ATOM 5194 C CE1 . PHE B 2 343 ? 117.185 85.509  130.564 1.00 104.04 ? 343 PHE B CE1 1 
ATOM 5195 C CE2 . PHE B 2 343 ? 116.962 85.508  132.945 1.00 104.04 ? 343 PHE B CE2 1 
ATOM 5196 C CZ  . PHE B 2 343 ? 116.601 85.005  131.711 1.00 104.04 ? 343 PHE B CZ  1 
ATOM 5197 N N   . LEU B 2 344 ? 121.997 89.318  133.754 1.00 109.77 ? 344 LEU B N   1 
ATOM 5198 C CA  . LEU B 2 344 ? 122.896 90.408  134.130 1.00 109.77 ? 344 LEU B CA  1 
ATOM 5199 C C   . LEU B 2 344 ? 124.346 90.092  133.767 1.00 109.77 ? 344 LEU B C   1 
ATOM 5200 O O   . LEU B 2 344 ? 125.048 90.945  133.216 1.00 109.77 ? 344 LEU B O   1 
ATOM 5201 C CB  . LEU B 2 344 ? 122.766 90.699  135.626 1.00 109.77 ? 344 LEU B CB  1 
ATOM 5202 C CG  . LEU B 2 344 ? 123.735 91.714  136.235 1.00 109.77 ? 344 LEU B CG  1 
ATOM 5203 C CD1 . LEU B 2 344 ? 123.524 93.091  135.630 1.00 109.77 ? 344 LEU B CD1 1 
ATOM 5204 C CD2 . LEU B 2 344 ? 123.586 91.764  137.746 1.00 109.77 ? 344 LEU B CD2 1 
ATOM 5205 N N   . VAL B 2 345 ? 124.790 88.856  134.024 1.00 110.75 ? 345 VAL B N   1 
ATOM 5206 C CA  . VAL B 2 345 ? 126.147 88.431  133.664 1.00 110.75 ? 345 VAL B CA  1 
ATOM 5207 C C   . VAL B 2 345 ? 126.312 88.370  132.142 1.00 110.75 ? 345 VAL B C   1 
ATOM 5208 O O   . VAL B 2 345 ? 127.343 88.799  131.590 1.00 110.75 ? 345 VAL B O   1 
ATOM 5209 C CB  . VAL B 2 345 ? 126.463 87.082  134.348 1.00 110.75 ? 345 VAL B CB  1 
ATOM 5210 C CG1 . VAL B 2 345 ? 127.708 86.411  133.774 1.00 110.75 ? 345 VAL B CG1 1 
ATOM 5211 C CG2 . VAL B 2 345 ? 126.630 87.280  135.848 1.00 110.75 ? 345 VAL B CG2 1 
ATOM 5212 N N   . ALA B 2 346 ? 125.274 87.888  131.442 1.00 113.78 ? 346 ALA B N   1 
ATOM 5213 C CA  . ALA B 2 346 ? 125.302 87.801  129.982 1.00 113.78 ? 346 ALA B CA  1 
ATOM 5214 C C   . ALA B 2 346 ? 125.343 89.176  129.321 1.00 113.78 ? 346 ALA B C   1 
ATOM 5215 O O   . ALA B 2 346 ? 125.928 89.326  128.243 1.00 113.78 ? 346 ALA B O   1 
ATOM 5216 C CB  . ALA B 2 346 ? 124.092 87.010  129.481 1.00 113.78 ? 346 ALA B CB  1 
ATOM 5217 N N   . LEU B 2 347 ? 124.734 90.186  129.946 1.00 114.02 ? 347 LEU B N   1 
ATOM 5218 C CA  . LEU B 2 347 ? 124.940 91.554  129.476 1.00 114.02 ? 347 LEU B CA  1 
ATOM 5219 C C   . LEU B 2 347 ? 126.285 92.110  129.935 1.00 114.02 ? 347 LEU B C   1 
ATOM 5220 O O   . LEU B 2 347 ? 126.835 93.016  129.297 1.00 114.02 ? 347 LEU B O   1 
ATOM 5221 C CB  . LEU B 2 347 ? 123.799 92.456  129.939 1.00 114.02 ? 347 LEU B CB  1 
ATOM 5222 C CG  . LEU B 2 347 ? 122.430 92.137  129.338 1.00 114.02 ? 347 LEU B CG  1 
ATOM 5223 C CD1 . LEU B 2 347 ? 121.352 92.998  129.968 1.00 114.02 ? 347 LEU B CD1 1 
ATOM 5224 C CD2 . LEU B 2 347 ? 122.462 92.321  127.830 1.00 114.02 ? 347 LEU B CD2 1 
ATOM 5225 N N   . LYS B 2 348 ? 126.823 91.594  131.047 1.00 122.13 ? 348 LYS B N   1 
ATOM 5226 C CA  . LYS B 2 348 ? 128.099 92.094  131.558 1.00 122.13 ? 348 LYS B CA  1 
ATOM 5227 C C   . LYS B 2 348 ? 129.287 91.642  130.717 1.00 122.13 ? 348 LYS B C   1 
ATOM 5228 O O   . LYS B 2 348 ? 130.355 92.264  130.790 1.00 122.13 ? 348 LYS B O   1 
ATOM 5229 C CB  . LYS B 2 348 ? 128.312 91.666  133.011 1.00 122.13 ? 348 LYS B CB  1 
ATOM 5230 C CG  . LYS B 2 348 ? 127.751 92.631  134.041 1.00 122.13 ? 348 LYS B CG  1 
ATOM 5231 C CD  . LYS B 2 348 ? 128.724 92.794  135.197 1.00 122.13 ? 348 LYS B CD  1 
ATOM 5232 C CE  . LYS B 2 348 ? 128.307 93.922  136.122 1.00 122.13 ? 348 LYS B CE  1 
ATOM 5233 N NZ  . LYS B 2 348 ? 128.984 93.822  137.442 1.00 122.13 ? 348 LYS B NZ  1 
ATOM 5234 N N   . PHE B 2 349 ? 129.139 90.564  129.933 1.00 124.93 ? 349 PHE B N   1 
ATOM 5235 C CA  . PHE B 2 349 ? 130.237 90.162  129.053 1.00 124.93 ? 349 PHE B CA  1 
ATOM 5236 C C   . PHE B 2 349 ? 130.358 91.155  127.889 1.00 124.93 ? 349 PHE B C   1 
ATOM 5237 O O   . PHE B 2 349 ? 131.452 91.385  127.368 1.00 124.93 ? 349 PHE B O   1 
ATOM 5238 C CB  . PHE B 2 349 ? 129.986 88.739  128.521 1.00 124.93 ? 349 PHE B CB  1 
ATOM 5239 C CG  . PHE B 2 349 ? 131.107 88.161  127.650 1.00 124.93 ? 349 PHE B CG  1 
ATOM 5240 C CD1 . PHE B 2 349 ? 130.854 87.073  126.822 1.00 124.93 ? 349 PHE B CD1 1 
ATOM 5241 C CD2 . PHE B 2 349 ? 132.444 88.520  127.856 1.00 124.93 ? 349 PHE B CD2 1 
ATOM 5242 C CE1 . PHE B 2 349 ? 131.870 86.491  126.068 1.00 124.93 ? 349 PHE B CE1 1 
ATOM 5243 C CE2 . PHE B 2 349 ? 133.464 87.958  127.111 1.00 124.93 ? 349 PHE B CE2 1 
ATOM 5244 C CZ  . PHE B 2 349 ? 133.177 86.936  126.230 1.00 124.93 ? 349 PHE B CZ  1 
ATOM 5245 N N   . MET B 2 350 ? 129.256 91.826  127.537 1.00 133.24 ? 350 MET B N   1 
ATOM 5246 C CA  . MET B 2 350 ? 129.104 92.514  126.257 1.00 133.24 ? 350 MET B CA  1 
ATOM 5247 C C   . MET B 2 350 ? 129.964 93.769  126.098 1.00 133.24 ? 350 MET B C   1 
ATOM 5248 O O   . MET B 2 350 ? 130.131 94.217  124.957 1.00 133.24 ? 350 MET B O   1 
ATOM 5249 C CB  . MET B 2 350 ? 127.633 92.881  126.057 1.00 133.24 ? 350 MET B CB  1 
ATOM 5250 C CG  . MET B 2 350 ? 126.665 91.695  125.920 1.00 133.24 ? 350 MET B CG  1 
ATOM 5251 S SD  . MET B 2 350 ? 126.936 90.583  124.519 1.00 133.24 ? 350 MET B SD  1 
ATOM 5252 C CE  . MET B 2 350 ? 127.735 89.177  125.296 1.00 133.24 ? 350 MET B CE  1 
ATOM 5253 N N   . GLN B 2 351 ? 130.539 94.297  127.189 1.00 128.94 ? 351 GLN B N   1 
ATOM 5254 C CA  . GLN B 2 351 ? 131.205 95.607  127.275 1.00 128.94 ? 351 GLN B CA  1 
ATOM 5255 C C   . GLN B 2 351 ? 130.307 96.729  126.743 1.00 128.94 ? 351 GLN B C   1 
ATOM 5256 O O   . GLN B 2 351 ? 130.696 97.536  125.897 1.00 128.94 ? 351 GLN B O   1 
ATOM 5257 C CB  . GLN B 2 351 ? 132.565 95.647  126.559 1.00 128.94 ? 351 GLN B CB  1 
ATOM 5258 C CG  . GLN B 2 351 ? 133.650 94.796  127.175 1.00 128.94 ? 351 GLN B CG  1 
ATOM 5259 C CD  . GLN B 2 351 ? 133.680 93.399  126.605 1.00 128.94 ? 351 GLN B CD  1 
ATOM 5260 O OE1 . GLN B 2 351 ? 133.145 93.147  125.524 1.00 128.94 ? 351 GLN B OE1 1 
ATOM 5261 N NE2 . GLN B 2 351 ? 134.290 92.474  127.335 1.00 128.94 ? 351 GLN B NE2 1 
ATOM 5262 N N   . VAL B 2 352 ? 129.089 96.757  127.267 1.00 125.77 ? 352 VAL B N   1 
ATOM 5263 C CA  . VAL B 2 352 ? 128.201 97.895  127.074 1.00 125.77 ? 352 VAL B CA  1 
ATOM 5264 C C   . VAL B 2 352 ? 128.080 98.634  128.403 1.00 125.77 ? 352 VAL B C   1 
ATOM 5265 O O   . VAL B 2 352 ? 127.986 98.033  129.480 1.00 125.77 ? 352 VAL B O   1 
ATOM 5266 C CB  . VAL B 2 352 ? 126.838 97.486  126.464 1.00 125.77 ? 352 VAL B CB  1 
ATOM 5267 C CG1 . VAL B 2 352 ? 127.064 96.892  125.084 1.00 125.77 ? 352 VAL B CG1 1 
ATOM 5268 C CG2 . VAL B 2 352 ? 126.128 96.445  127.309 1.00 125.77 ? 352 VAL B CG2 1 
ATOM 5269 N N   . GLU B 2 353 ? 128.163 99.959  128.318 1.00 124.99 ? 353 GLU B N   1 
ATOM 5270 C CA  . GLU B 2 353 ? 128.493 100.768 129.485 1.00 124.99 ? 353 GLU B CA  1 
ATOM 5271 C C   . GLU B 2 353 ? 127.268 100.998 130.364 1.00 124.99 ? 353 GLU B C   1 
ATOM 5272 O O   . GLU B 2 353 ? 126.161 101.210 129.856 1.00 124.99 ? 353 GLU B O   1 
ATOM 5273 C CB  . GLU B 2 353 ? 129.097 102.104 129.025 1.00 124.99 ? 353 GLU B CB  1 
ATOM 5274 C CG  . GLU B 2 353 ? 129.557 103.066 130.130 1.00 124.99 ? 353 GLU B CG  1 
ATOM 5275 C CD  . GLU B 2 353 ? 130.966 102.782 130.651 1.00 124.99 ? 353 GLU B CD  1 
ATOM 5276 O OE1 . GLU B 2 353 ? 131.536 101.712 130.346 1.00 124.99 ? 353 GLU B OE1 1 
ATOM 5277 O OE2 . GLU B 2 353 ? 131.505 103.638 131.383 1.00 124.99 ? 353 GLU B OE2 1 
ATOM 5278 N N   . ASP B 2 354 ? 127.490 100.936 131.685 1.00 121.02 ? 354 ASP B N   1 
ATOM 5279 C CA  . ASP B 2 354 ? 126.534 101.251 132.754 1.00 121.02 ? 354 ASP B CA  1 
ATOM 5280 C C   . ASP B 2 354 ? 125.307 100.335 132.690 1.00 121.02 ? 354 ASP B C   1 
ATOM 5281 O O   . ASP B 2 354 ? 124.174 100.760 132.455 1.00 121.02 ? 354 ASP B O   1 
ATOM 5282 C CB  . ASP B 2 354 ? 126.134 102.734 132.725 1.00 121.02 ? 354 ASP B CB  1 
ATOM 5283 C CG  . ASP B 2 354 ? 125.550 103.213 134.044 1.00 121.02 ? 354 ASP B CG  1 
ATOM 5284 O OD1 . ASP B 2 354 ? 125.500 102.419 135.007 1.00 121.02 ? 354 ASP B OD1 1 
ATOM 5285 O OD2 . ASP B 2 354 ? 125.147 104.392 134.120 1.00 121.02 ? 354 ASP B OD2 1 
ATOM 5286 N N   . VAL B 2 355 ? 125.575 99.052  132.908 1.00 112.38 ? 355 VAL B N   1 
ATOM 5287 C CA  . VAL B 2 355 ? 124.542 98.025  132.956 1.00 112.38 ? 355 VAL B CA  1 
ATOM 5288 C C   . VAL B 2 355 ? 124.522 97.461  134.369 1.00 112.38 ? 355 VAL B C   1 
ATOM 5289 O O   . VAL B 2 355 ? 125.541 96.963  134.864 1.00 112.38 ? 355 VAL B O   1 
ATOM 5290 C CB  . VAL B 2 355 ? 124.779 96.924  131.915 1.00 112.38 ? 355 VAL B CB  1 
ATOM 5291 C CG1 . VAL B 2 355 ? 123.851 95.744  132.154 1.00 112.38 ? 355 VAL B CG1 1 
ATOM 5292 C CG2 . VAL B 2 355 ? 124.558 97.485  130.529 1.00 112.38 ? 355 VAL B CG2 1 
ATOM 5293 N N   . ASP B 2 356 ? 123.364 97.539  135.016 1.00 106.32 ? 356 ASP B N   1 
ATOM 5294 C CA  . ASP B 2 356 ? 123.180 97.065  136.377 1.00 106.32 ? 356 ASP B CA  1 
ATOM 5295 C C   . ASP B 2 356 ? 121.879 96.278  136.463 1.00 106.32 ? 356 ASP B C   1 
ATOM 5296 O O   . ASP B 2 356 ? 121.289 95.897  135.449 1.00 106.32 ? 356 ASP B O   1 
ATOM 5297 C CB  . ASP B 2 356 ? 123.242 98.235  137.381 1.00 106.32 ? 356 ASP B CB  1 
ATOM 5298 C CG  . ASP B 2 356 ? 122.137 99.271  137.180 1.00 106.32 ? 356 ASP B CG  1 
ATOM 5299 O OD1 . ASP B 2 356 ? 122.477 100.402 136.773 1.00 106.32 ? 356 ASP B OD1 1 
ATOM 5300 O OD2 . ASP B 2 356 ? 120.956 99.010  137.491 1.00 106.32 ? 356 ASP B OD2 1 
ATOM 5301 N N   . ILE B 2 357 ? 121.437 96.034  137.700 1.00 101.77 ? 357 ILE B N   1 
ATOM 5302 C CA  . ILE B 2 357 ? 120.297 95.157  137.941 1.00 101.77 ? 357 ILE B CA  1 
ATOM 5303 C C   . ILE B 2 357 ? 118.974 95.828  137.565 1.00 101.77 ? 357 ILE B C   1 
ATOM 5304 O O   . ILE B 2 357 ? 118.000 95.140  137.238 1.00 101.77 ? 357 ILE B O   1 
ATOM 5305 C CB  . ILE B 2 357 ? 120.340 94.677  139.419 1.00 101.77 ? 357 ILE B CB  1 
ATOM 5306 C CG1 . ILE B 2 357 ? 119.374 93.514  139.683 1.00 101.77 ? 357 ILE B CG1 1 
ATOM 5307 C CG2 . ILE B 2 357 ? 120.111 95.831  140.396 1.00 101.77 ? 357 ILE B CG2 1 
ATOM 5308 C CD1 . ILE B 2 357 ? 119.736 92.241  138.951 1.00 101.77 ? 357 ILE B CD1 1 
ATOM 5309 N N   . ASP B 2 358 ? 118.928 97.162  137.532 1.00 105.40 ? 358 ASP B N   1 
ATOM 5310 C CA  . ASP B 2 358 ? 117.700 97.843  137.140 1.00 105.40 ? 358 ASP B CA  1 
ATOM 5311 C C   . ASP B 2 358 ? 117.535 97.932  135.629 1.00 105.40 ? 358 ASP B C   1 
ATOM 5312 O O   . ASP B 2 358 ? 116.399 98.010  135.149 1.00 105.40 ? 358 ASP B O   1 
ATOM 5313 C CB  . ASP B 2 358 ? 117.650 99.248  137.744 1.00 105.40 ? 358 ASP B CB  1 
ATOM 5314 C CG  . ASP B 2 358 ? 117.479 99.229  139.249 1.00 105.40 ? 358 ASP B CG  1 
ATOM 5315 O OD1 . ASP B 2 358 ? 116.868 98.271  139.767 1.00 105.40 ? 358 ASP B OD1 1 
ATOM 5316 O OD2 . ASP B 2 358 ? 117.957 100.172 139.914 1.00 105.40 ? 358 ASP B OD2 1 
ATOM 5317 N N   . GLU B 2 359 ? 118.634 97.923  134.876 1.00 96.46  ? 359 GLU B N   1 
ATOM 5318 C CA  . GLU B 2 359 ? 118.581 97.983  133.422 1.00 96.46  ? 359 GLU B CA  1 
ATOM 5319 C C   . GLU B 2 359 ? 118.082 96.685  132.796 1.00 96.46  ? 359 GLU B C   1 
ATOM 5320 O O   . GLU B 2 359 ? 117.248 96.736  131.882 1.00 96.46  ? 359 GLU B O   1 
ATOM 5321 C CB  . GLU B 2 359 ? 119.971 98.339  132.870 1.00 96.46  ? 359 GLU B CB  1 
ATOM 5322 C CG  . GLU B 2 359 ? 120.141 98.183  131.367 1.00 96.46  ? 359 GLU B CG  1 
ATOM 5323 C CD  . GLU B 2 359 ? 119.301 99.172  130.583 1.00 96.46  ? 359 GLU B CD  1 
ATOM 5324 O OE1 . GLU B 2 359 ? 118.750 98.785  129.532 1.00 96.46  ? 359 GLU B OE1 1 
ATOM 5325 O OE2 . GLU B 2 359 ? 119.195 100.338 131.017 1.00 96.46  ? 359 GLU B OE2 1 
ATOM 5326 N N   . VAL B 2 360 ? 118.540 95.531  133.289 1.00 97.82  ? 360 VAL B N   1 
ATOM 5327 C CA  . VAL B 2 360 ? 118.107 94.229  132.792 1.00 97.82  ? 360 VAL B CA  1 
ATOM 5328 C C   . VAL B 2 360 ? 116.645 93.936  133.136 1.00 97.82  ? 360 VAL B C   1 
ATOM 5329 O O   . VAL B 2 360 ? 115.965 93.221  132.385 1.00 97.82  ? 360 VAL B O   1 
ATOM 5330 C CB  . VAL B 2 360 ? 119.067 93.125  133.307 1.00 97.82  ? 360 VAL B CB  1 
ATOM 5331 C CG1 . VAL B 2 360 ? 119.006 92.959  134.828 1.00 97.82  ? 360 VAL B CG1 1 
ATOM 5332 C CG2 . VAL B 2 360 ? 118.881 91.792  132.579 1.00 97.82  ? 360 VAL B CG2 1 
ATOM 5333 N N   . GLN B 2 361 ? 116.116 94.536  134.207 1.00 99.12  ? 361 GLN B N   1 
ATOM 5334 C CA  . GLN B 2 361 ? 114.723 94.362  134.599 1.00 99.12  ? 361 GLN B CA  1 
ATOM 5335 C C   . GLN B 2 361 ? 113.797 95.178  133.695 1.00 99.12  ? 361 GLN B C   1 
ATOM 5336 O O   . GLN B 2 361 ? 112.625 94.823  133.522 1.00 99.12  ? 361 GLN B O   1 
ATOM 5337 C CB  . GLN B 2 361 ? 114.570 94.732  136.085 1.00 99.12  ? 361 GLN B CB  1 
ATOM 5338 C CG  . GLN B 2 361 ? 113.177 94.673  136.715 1.00 99.12  ? 361 GLN B CG  1 
ATOM 5339 C CD  . GLN B 2 361 ? 112.437 95.993  136.646 1.00 99.12  ? 361 GLN B CD  1 
ATOM 5340 O OE1 . GLN B 2 361 ? 113.041 97.045  136.440 1.00 99.12  ? 361 GLN B OE1 1 
ATOM 5341 N NE2 . GLN B 2 361 ? 111.122 95.943  136.818 1.00 99.12  ? 361 GLN B NE2 1 
ATOM 5342 N N   . CYS B 2 362 ? 114.322 96.220  133.054 1.00 89.92  ? 362 CYS B N   1 
ATOM 5343 C CA  . CYS B 2 362 ? 113.548 97.111  132.199 1.00 89.92  ? 362 CYS B CA  1 
ATOM 5344 C C   . CYS B 2 362 ? 113.325 96.590  130.788 1.00 89.92  ? 362 CYS B C   1 
ATOM 5345 O O   . CYS B 2 362 ? 112.216 96.736  130.265 1.00 89.92  ? 362 CYS B O   1 
ATOM 5346 C CB  . CYS B 2 362 ? 114.242 98.477  132.111 1.00 89.92  ? 362 CYS B CB  1 
ATOM 5347 S SG  . CYS B 2 362 ? 113.577 99.623  130.884 1.00 89.92  ? 362 CYS B SG  1 
ATOM 5348 N N   . ILE B 2 363 ? 114.345 95.991  130.165 1.00 84.88  ? 363 ILE B N   1 
ATOM 5349 C CA  . ILE B 2 363 ? 114.263 95.572  128.764 1.00 84.88  ? 363 ILE B CA  1 
ATOM 5350 C C   . ILE B 2 363 ? 113.323 94.375  128.629 1.00 84.88  ? 363 ILE B C   1 
ATOM 5351 O O   . ILE B 2 363 ? 112.587 94.236  127.642 1.00 84.88  ? 363 ILE B O   1 
ATOM 5352 C CB  . ILE B 2 363 ? 115.678 95.268  128.231 1.00 84.88  ? 363 ILE B CB  1 
ATOM 5353 C CG1 . ILE B 2 363 ? 116.535 96.535  128.274 1.00 84.88  ? 363 ILE B CG1 1 
ATOM 5354 C CG2 . ILE B 2 363 ? 115.670 94.777  126.790 1.00 84.88  ? 363 ILE B CG2 1 
ATOM 5355 C CD1 . ILE B 2 363 ? 115.991 97.683  127.445 1.00 84.88  ? 363 ILE B CD1 1 
ATOM 5356 N N   . LEU B 2 364 ? 113.298 93.528  129.662 1.00 77.36  ? 364 LEU B N   1 
ATOM 5357 C CA  . LEU B 2 364 ? 112.435 92.351  129.689 1.00 77.36  ? 364 LEU B CA  1 
ATOM 5358 C C   . LEU B 2 364 ? 110.953 92.718  129.745 1.00 77.36  ? 364 LEU B C   1 
ATOM 5359 O O   . LEU B 2 364 ? 110.125 92.060  129.104 1.00 77.36  ? 364 LEU B O   1 
ATOM 5360 C CB  . LEU B 2 364 ? 112.825 91.482  130.882 1.00 77.36  ? 364 LEU B CB  1 
ATOM 5361 C CG  . LEU B 2 364 ? 112.236 90.089  131.058 1.00 77.36  ? 364 LEU B CG  1 
ATOM 5362 C CD1 . LEU B 2 364 ? 112.409 89.270  129.796 1.00 77.36  ? 364 LEU B CD1 1 
ATOM 5363 C CD2 . LEU B 2 364 ? 112.936 89.429  132.227 1.00 77.36  ? 364 LEU B CD2 1 
ATOM 5364 N N   . ALA B 2 365 ? 110.604 93.783  130.475 1.00 78.15  ? 365 ALA B N   1 
ATOM 5365 C CA  . ALA B 2 365 ? 109.225 94.265  130.475 1.00 78.15  ? 365 ALA B CA  1 
ATOM 5366 C C   . ALA B 2 365 ? 108.842 94.886  129.135 1.00 78.15  ? 365 ALA B C   1 
ATOM 5367 O O   . ALA B 2 365 ? 107.674 94.814  128.732 1.00 78.15  ? 365 ALA B O   1 
ATOM 5368 C CB  . ALA B 2 365 ? 109.019 95.273  131.604 1.00 78.15  ? 365 ALA B CB  1 
ATOM 5369 N N   . ASN B 2 366 ? 109.808 95.491  128.438 1.00 75.74  ? 366 ASN B N   1 
ATOM 5370 C CA  . ASN B 2 366 ? 109.570 95.993  127.088 1.00 75.74  ? 366 ASN B CA  1 
ATOM 5371 C C   . ASN B 2 366 ? 109.344 94.848  126.108 1.00 75.74  ? 366 ASN B C   1 
ATOM 5372 O O   . ASN B 2 366 ? 108.566 94.973  125.155 1.00 75.74  ? 366 ASN B O   1 
ATOM 5373 C CB  . ASN B 2 366 ? 110.748 96.857  126.638 1.00 75.74  ? 366 ASN B CB  1 
ATOM 5374 C CG  . ASN B 2 366 ? 110.608 98.297  127.066 1.00 75.74  ? 366 ASN B CG  1 
ATOM 5375 O OD1 . ASN B 2 366 ? 109.806 98.624  127.940 1.00 75.74  ? 366 ASN B OD1 1 
ATOM 5376 N ND2 . ASN B 2 366 ? 111.397 99.171  126.456 1.00 75.74  ? 366 ASN B ND2 1 
ATOM 5377 N N   . LEU B 2 367 ? 110.035 93.727  126.319 1.00 71.37  ? 367 LEU B N   1 
ATOM 5378 C CA  . LEU B 2 367 ? 109.822 92.530  125.514 1.00 71.37  ? 367 LEU B CA  1 
ATOM 5379 C C   . LEU B 2 367 ? 108.460 91.917  125.805 1.00 71.37  ? 367 LEU B C   1 
ATOM 5380 O O   . LEU B 2 367 ? 107.820 91.360  124.907 1.00 71.37  ? 367 LEU B O   1 
ATOM 5381 C CB  . LEU B 2 367 ? 110.918 91.498  125.770 1.00 71.37  ? 367 LEU B CB  1 
ATOM 5382 C CG  . LEU B 2 367 ? 112.312 91.820  125.242 1.00 71.37  ? 367 LEU B CG  1 
ATOM 5383 C CD1 . LEU B 2 367 ? 113.258 90.703  125.617 1.00 71.37  ? 367 LEU B CD1 1 
ATOM 5384 C CD2 . LEU B 2 367 ? 112.279 92.013  123.744 1.00 71.37  ? 367 LEU B CD2 1 
ATOM 5385 N N   . ILE B 2 368 ? 108.025 91.994  127.063 1.00 66.96  ? 368 ILE B N   1 
ATOM 5386 C CA  . ILE B 2 368 ? 106.696 91.525  127.441 1.00 66.96  ? 368 ILE B CA  1 
ATOM 5387 C C   . ILE B 2 368 ? 105.581 92.377  126.832 1.00 66.96  ? 368 ILE B C   1 
ATOM 5388 O O   . ILE B 2 368 ? 104.627 91.811  126.271 1.00 66.96  ? 368 ILE B O   1 
ATOM 5389 C CB  . ILE B 2 368 ? 106.570 91.446  128.981 1.00 66.96  ? 368 ILE B CB  1 
ATOM 5390 C CG1 . ILE B 2 368 ? 107.374 90.259  129.509 1.00 66.96  ? 368 ILE B CG1 1 
ATOM 5391 C CG2 . ILE B 2 368 ? 105.126 91.284  129.439 1.00 66.96  ? 368 ILE B CG2 1 
ATOM 5392 C CD1 . ILE B 2 368 ? 107.453 90.194  131.014 1.00 66.96  ? 368 ILE B CD1 1 
ATOM 5393 N N   . TYR B 2 369 ? 105.701 93.708  126.867 1.00 72.42  ? 369 TYR B N   1 
ATOM 5394 C CA  . TYR B 2 369 ? 104.663 94.593  126.340 1.00 72.42  ? 369 TYR B CA  1 
ATOM 5395 C C   . TYR B 2 369 ? 104.520 94.523  124.822 1.00 72.42  ? 369 TYR B C   1 
ATOM 5396 O O   . TYR B 2 369 ? 103.398 94.513  124.306 1.00 72.42  ? 369 TYR B O   1 
ATOM 5397 C CB  . TYR B 2 369 ? 104.923 96.043  126.751 1.00 72.42  ? 369 TYR B CB  1 
ATOM 5398 C CG  . TYR B 2 369 ? 103.821 96.984  126.313 1.00 72.42  ? 369 TYR B CG  1 
ATOM 5399 C CD1 . TYR B 2 369 ? 102.484 96.690  126.576 1.00 72.42  ? 369 TYR B CD1 1 
ATOM 5400 C CD2 . TYR B 2 369 ? 104.113 98.150  125.611 1.00 72.42  ? 369 TYR B CD2 1 
ATOM 5401 C CE1 . TYR B 2 369 ? 101.470 97.539  126.167 1.00 72.42  ? 369 TYR B CE1 1 
ATOM 5402 C CE2 . TYR B 2 369 ? 103.105 99.007  125.198 1.00 72.42  ? 369 TYR B CE2 1 
ATOM 5403 C CZ  . TYR B 2 369 ? 101.787 98.694  125.479 1.00 72.42  ? 369 TYR B CZ  1 
ATOM 5404 O OH  . TYR B 2 369 ? 100.782 99.538  125.070 1.00 72.42  ? 369 TYR B OH  1 
ATOM 5405 N N   . MET B 2 370 ? 105.636 94.471  124.097 1.00 73.92  ? 370 MET B N   1 
ATOM 5406 C CA  . MET B 2 370 ? 105.573 94.455  122.639 1.00 73.92  ? 370 MET B CA  1 
ATOM 5407 C C   . MET B 2 370 ? 105.182 93.081  122.105 1.00 73.92  ? 370 MET B C   1 
ATOM 5408 O O   . MET B 2 370 ? 104.755 92.959  120.953 1.00 73.92  ? 370 MET B O   1 
ATOM 5409 C CB  . MET B 2 370 ? 106.905 94.910  122.041 1.00 73.92  ? 370 MET B CB  1 
ATOM 5410 C CG  . MET B 2 370 ? 107.053 96.426  121.998 1.00 73.92  ? 370 MET B CG  1 
ATOM 5411 S SD  . MET B 2 370 ? 108.752 97.035  121.976 1.00 73.92  ? 370 MET B SD  1 
ATOM 5412 C CE  . MET B 2 370 ? 109.595 95.723  121.100 1.00 73.92  ? 370 MET B CE  1 
ATOM 5413 N N   . GLY B 2 371 ? 105.320 92.044  122.927 1.00 67.88  ? 371 GLY B N   1 
ATOM 5414 C CA  . GLY B 2 371 ? 104.844 90.722  122.583 1.00 67.88  ? 371 GLY B CA  1 
ATOM 5415 C C   . GLY B 2 371 ? 105.894 89.726  122.142 1.00 67.88  ? 371 GLY B C   1 
ATOM 5416 O O   . GLY B 2 371 ? 105.528 88.642  121.672 1.00 67.88  ? 371 GLY B O   1 
ATOM 5417 N N   . HIS B 2 372 ? 107.183 90.055  122.262 1.00 63.63  ? 372 HIS B N   1 
ATOM 5418 C CA  . HIS B 2 372 ? 108.225 89.109  121.875 1.00 63.63  ? 372 HIS B CA  1 
ATOM 5419 C C   . HIS B 2 372 ? 108.343 87.965  122.874 1.00 63.63  ? 372 HIS B C   1 
ATOM 5420 O O   . HIS B 2 372 ? 108.436 86.799  122.478 1.00 63.63  ? 372 HIS B O   1 
ATOM 5421 C CB  . HIS B 2 372 ? 109.566 89.827  121.734 1.00 63.63  ? 372 HIS B CB  1 
ATOM 5422 C CG  . HIS B 2 372 ? 109.603 90.830  120.626 1.00 63.63  ? 372 HIS B CG  1 
ATOM 5423 N ND1 . HIS B 2 372 ? 109.743 90.472  119.303 1.00 63.63  ? 372 HIS B ND1 1 
ATOM 5424 C CD2 . HIS B 2 372 ? 109.519 92.180  120.643 1.00 63.63  ? 372 HIS B CD2 1 
ATOM 5425 C CE1 . HIS B 2 372 ? 109.745 91.559  118.553 1.00 63.63  ? 372 HIS B CE1 1 
ATOM 5426 N NE2 . HIS B 2 372 ? 109.610 92.609  119.342 1.00 63.63  ? 372 HIS B NE2 1 
ATOM 5427 N N   . VAL B 2 373 ? 108.338 88.275  124.168 1.00 74.16  ? 373 VAL B N   1 
ATOM 5428 C CA  . VAL B 2 373 ? 108.531 87.290  125.226 1.00 74.16  ? 373 VAL B CA  1 
ATOM 5429 C C   . VAL B 2 373 ? 107.283 87.264  126.096 1.00 74.16  ? 373 VAL B C   1 
ATOM 5430 O O   . VAL B 2 373 ? 106.872 88.301  126.626 1.00 74.16  ? 373 VAL B O   1 
ATOM 5431 C CB  . VAL B 2 373 ? 109.776 87.607  126.076 1.00 74.16  ? 373 VAL B CB  1 
ATOM 5432 C CG1 . VAL B 2 373 ? 109.945 86.580  127.182 1.00 74.16  ? 373 VAL B CG1 1 
ATOM 5433 C CG2 . VAL B 2 373 ? 111.021 87.664  125.207 1.00 74.16  ? 373 VAL B CG2 1 
ATOM 5434 N N   . LYS B 2 374 ? 106.686 86.086  126.247 1.00 81.48  ? 374 LYS B N   1 
ATOM 5435 C CA  . LYS B 2 374 ? 105.547 85.933  127.136 1.00 81.48  ? 374 LYS B CA  1 
ATOM 5436 C C   . LYS B 2 374 ? 106.028 85.769  128.577 1.00 81.48  ? 374 LYS B C   1 
ATOM 5437 O O   . LYS B 2 374 ? 107.194 85.470  128.842 1.00 81.48  ? 374 LYS B O   1 
ATOM 5438 C CB  . LYS B 2 374 ? 104.684 84.750  126.703 1.00 81.48  ? 374 LYS B CB  1 
ATOM 5439 C CG  . LYS B 2 374 ? 104.064 84.909  125.328 1.00 81.48  ? 374 LYS B CG  1 
ATOM 5440 C CD  . LYS B 2 374 ? 102.734 84.183  125.239 1.00 81.48  ? 374 LYS B CD  1 
ATOM 5441 C CE  . LYS B 2 374 ? 101.756 84.932  124.349 1.00 81.48  ? 374 LYS B CE  1 
ATOM 5442 N NZ  . LYS B 2 374 ? 100.648 84.056  123.881 1.00 81.48  ? 374 LYS B NZ  1 
ATOM 5443 N N   . GLY B 2 375 ? 105.118 85.967  129.520 1.00 79.62  ? 375 GLY B N   1 
ATOM 5444 C CA  . GLY B 2 375 ? 105.408 85.796  130.927 1.00 79.62  ? 375 GLY B CA  1 
ATOM 5445 C C   . GLY B 2 375 ? 105.269 87.080  131.721 1.00 79.62  ? 375 GLY B C   1 
ATOM 5446 O O   . GLY B 2 375 ? 104.742 88.092  131.251 1.00 79.62  ? 375 GLY B O   1 
ATOM 5447 N N   . TYR B 2 376 ? 105.759 87.029  132.959 1.00 78.02  ? 376 TYR B N   1 
ATOM 5448 C CA  . TYR B 2 376 ? 105.653 88.158  133.875 1.00 78.02  ? 376 TYR B CA  1 
ATOM 5449 C C   . TYR B 2 376 ? 106.904 88.226  134.737 1.00 78.02  ? 376 TYR B C   1 
ATOM 5450 O O   . TYR B 2 376 ? 107.455 87.187  135.111 1.00 78.02  ? 376 TYR B O   1 
ATOM 5451 C CB  . TYR B 2 376 ? 104.396 88.049  134.754 1.00 78.02  ? 376 TYR B CB  1 
ATOM 5452 C CG  . TYR B 2 376 ? 104.347 86.855  135.693 1.00 78.02  ? 376 TYR B CG  1 
ATOM 5453 C CD1 . TYR B 2 376 ? 103.885 85.616  135.254 1.00 78.02  ? 376 TYR B CD1 1 
ATOM 5454 C CD2 . TYR B 2 376 ? 104.722 86.978  137.032 1.00 78.02  ? 376 TYR B CD2 1 
ATOM 5455 C CE1 . TYR B 2 376 ? 103.830 84.527  136.109 1.00 78.02  ? 376 TYR B CE1 1 
ATOM 5456 C CE2 . TYR B 2 376 ? 104.671 85.895  137.894 1.00 78.02  ? 376 TYR B CE2 1 
ATOM 5457 C CZ  . TYR B 2 376 ? 104.223 84.674  137.427 1.00 78.02  ? 376 TYR B CZ  1 
ATOM 5458 O OH  . TYR B 2 376 ? 104.166 83.596  138.280 1.00 78.02  ? 376 TYR B OH  1 
ATOM 5459 N N   . ILE B 2 377 ? 107.335 89.444  135.063 1.00 82.61  ? 377 ILE B N   1 
ATOM 5460 C CA  . ILE B 2 377 ? 108.502 89.649  135.914 1.00 82.61  ? 377 ILE B CA  1 
ATOM 5461 C C   . ILE B 2 377 ? 108.065 89.729  137.369 1.00 82.61  ? 377 ILE B C   1 
ATOM 5462 O O   . ILE B 2 377 ? 107.492 90.735  137.801 1.00 82.61  ? 377 ILE B O   1 
ATOM 5463 C CB  . ILE B 2 377 ? 109.276 90.920  135.521 1.00 82.61  ? 377 ILE B CB  1 
ATOM 5464 C CG1 . ILE B 2 377 ? 109.601 90.920  134.028 1.00 82.61  ? 377 ILE B CG1 1 
ATOM 5465 C CG2 . ILE B 2 377 ? 110.545 91.041  136.347 1.00 82.61  ? 377 ILE B CG2 1 
ATOM 5466 C CD1 . ILE B 2 377 ? 110.272 92.193  133.559 1.00 82.61  ? 377 ILE B CD1 1 
ATOM 5467 N N   . SER B 2 378 ? 108.332 88.674  138.135 1.00 95.32  ? 378 SER B N   1 
ATOM 5468 C CA  . SER B 2 378 ? 108.056 88.706  139.564 1.00 95.32  ? 378 SER B CA  1 
ATOM 5469 C C   . SER B 2 378 ? 109.105 89.546  140.280 1.00 95.32  ? 378 SER B C   1 
ATOM 5470 O O   . SER B 2 378 ? 110.307 89.397  140.049 1.00 95.32  ? 378 SER B O   1 
ATOM 5471 C CB  . SER B 2 378 ? 108.035 87.286  140.133 1.00 95.32  ? 378 SER B CB  1 
ATOM 5472 O OG  . SER B 2 378 ? 107.844 87.304  141.537 1.00 95.32  ? 378 SER B OG  1 
ATOM 5473 N N   . HIS B 2 379 ? 108.641 90.441  141.152 1.00 102.75 ? 379 HIS B N   1 
ATOM 5474 C CA  . HIS B 2 379 ? 109.527 91.315  141.905 1.00 102.75 ? 379 HIS B CA  1 
ATOM 5475 C C   . HIS B 2 379 ? 109.896 90.759  143.273 1.00 102.75 ? 379 HIS B C   1 
ATOM 5476 O O   . HIS B 2 379 ? 110.996 91.041  143.762 1.00 102.75 ? 379 HIS B O   1 
ATOM 5477 C CB  . HIS B 2 379 ? 108.887 92.702  142.074 1.00 102.75 ? 379 HIS B CB  1 
ATOM 5478 C CG  . HIS B 2 379 ? 109.805 93.727  142.663 1.00 102.75 ? 379 HIS B CG  1 
ATOM 5479 N ND1 . HIS B 2 379 ? 110.886 94.240  141.978 1.00 102.75 ? 379 HIS B ND1 1 
ATOM 5480 C CD2 . HIS B 2 379 ? 109.807 94.331  143.875 1.00 102.75 ? 379 HIS B CD2 1 
ATOM 5481 C CE1 . HIS B 2 379 ? 111.512 95.118  142.741 1.00 102.75 ? 379 HIS B CE1 1 
ATOM 5482 N NE2 . HIS B 2 379 ? 110.877 95.192  143.897 1.00 102.75 ? 379 HIS B NE2 1 
ATOM 5483 N N   . GLN B 2 380 ? 109.020 89.971  143.893 1.00 108.75 ? 380 GLN B N   1 
ATOM 5484 C CA  . GLN B 2 380 ? 109.276 89.408  145.212 1.00 108.75 ? 380 GLN B CA  1 
ATOM 5485 C C   . GLN B 2 380 ? 110.292 88.273  145.188 1.00 108.75 ? 380 GLN B C   1 
ATOM 5486 O O   . GLN B 2 380 ? 110.993 88.063  146.184 1.00 108.75 ? 380 GLN B O   1 
ATOM 5487 C CB  . GLN B 2 380 ? 107.959 88.918  145.830 1.00 108.75 ? 380 GLN B CB  1 
ATOM 5488 C CG  . GLN B 2 380 ? 107.978 88.762  147.344 1.00 108.75 ? 380 GLN B CG  1 
ATOM 5489 C CD  . GLN B 2 380 ? 108.025 87.314  147.780 1.00 108.75 ? 380 GLN B CD  1 
ATOM 5490 O OE1 . GLN B 2 380 ? 107.398 86.450  147.168 1.00 108.75 ? 380 GLN B OE1 1 
ATOM 5491 N NE2 . GLN B 2 380 ? 108.772 87.039  148.842 1.00 108.75 ? 380 GLN B NE2 1 
ATOM 5492 N N   . HIS B 2 381 ? 110.407 87.553  144.071 1.00 103.93 ? 381 HIS B N   1 
ATOM 5493 C CA  . HIS B 2 381 ? 111.360 86.459  143.947 1.00 103.93 ? 381 HIS B CA  1 
ATOM 5494 C C   . HIS B 2 381 ? 112.470 86.721  142.940 1.00 103.93 ? 381 HIS B C   1 
ATOM 5495 O O   . HIS B 2 381 ? 113.434 85.946  142.910 1.00 103.93 ? 381 HIS B O   1 
ATOM 5496 C CB  . HIS B 2 381 ? 110.634 85.161  143.564 1.00 103.93 ? 381 HIS B CB  1 
ATOM 5497 C CG  . HIS B 2 381 ? 109.789 84.594  144.661 1.00 103.93 ? 381 HIS B CG  1 
ATOM 5498 N ND1 . HIS B 2 381 ? 108.772 83.693  144.429 1.00 103.93 ? 381 HIS B ND1 1 
ATOM 5499 C CD2 . HIS B 2 381 ? 109.820 84.790  146.000 1.00 103.93 ? 381 HIS B CD2 1 
ATOM 5500 C CE1 . HIS B 2 381 ? 108.207 83.365  145.577 1.00 103.93 ? 381 HIS B CE1 1 
ATOM 5501 N NE2 . HIS B 2 381 ? 108.824 84.017  146.546 1.00 103.93 ? 381 HIS B NE2 1 
ATOM 5502 N N   . GLN B 2 382 ? 112.348 87.782  142.131 1.00 98.83  ? 382 GLN B N   1 
ATOM 5503 C CA  . GLN B 2 382 ? 113.294 88.192  141.079 1.00 98.83  ? 382 GLN B CA  1 
ATOM 5504 C C   . GLN B 2 382 ? 113.538 87.076  140.059 1.00 98.83  ? 382 GLN B C   1 
ATOM 5505 O O   . GLN B 2 382 ? 114.658 86.845  139.599 1.00 98.83  ? 382 GLN B O   1 
ATOM 5506 C CB  . GLN B 2 382 ? 114.614 88.697  141.674 1.00 98.83  ? 382 GLN B CB  1 
ATOM 5507 C CG  . GLN B 2 382 ? 114.449 89.790  142.711 1.00 98.83  ? 382 GLN B CG  1 
ATOM 5508 C CD  . GLN B 2 382 ? 114.011 91.105  142.098 1.00 98.83  ? 382 GLN B CD  1 
ATOM 5509 O OE1 . GLN B 2 382 ? 114.475 91.486  141.025 1.00 98.83  ? 382 GLN B OE1 1 
ATOM 5510 N NE2 . GLN B 2 382 ? 113.114 91.806  142.781 1.00 98.83  ? 382 GLN B NE2 1 
ATOM 5511 N N   . LYS B 2 383 ? 112.457 86.380  139.709 1.00 95.80  ? 383 LYS B N   1 
ATOM 5512 C CA  . LYS B 2 383 ? 112.514 85.289  138.745 1.00 95.80  ? 383 LYS B CA  1 
ATOM 5513 C C   . LYS B 2 383 ? 111.452 85.505  137.679 1.00 95.80  ? 383 LYS B C   1 
ATOM 5514 O O   . LYS B 2 383 ? 110.329 85.908  137.993 1.00 95.80  ? 383 LYS B O   1 
ATOM 5515 C CB  . LYS B 2 383 ? 112.311 83.928  139.425 1.00 95.80  ? 383 LYS B CB  1 
ATOM 5516 C CG  . LYS B 2 383 ? 113.406 83.550  140.412 1.00 95.80  ? 383 LYS B CG  1 
ATOM 5517 C CD  . LYS B 2 383 ? 113.619 82.047  140.464 1.00 95.80  ? 383 LYS B CD  1 
ATOM 5518 C CE  . LYS B 2 383 ? 114.737 81.618  139.529 1.00 95.80  ? 383 LYS B CE  1 
ATOM 5519 N NZ  . LYS B 2 383 ? 114.642 80.176  139.169 1.00 95.80  ? 383 LYS B NZ  1 
ATOM 5520 N N   . LEU B 2 384 ? 111.810 85.235  136.425 1.00 85.02  ? 384 LEU B N   1 
ATOM 5521 C CA  . LEU B 2 384 ? 110.895 85.391  135.294 1.00 85.02  ? 384 LEU B CA  1 
ATOM 5522 C C   . LEU B 2 384 ? 110.243 84.048  134.995 1.00 85.02  ? 384 LEU B C   1 
ATOM 5523 O O   . LEU B 2 384 ? 110.902 83.111  134.539 1.00 85.02  ? 384 LEU B O   1 
ATOM 5524 C CB  . LEU B 2 384 ? 111.632 85.921  134.069 1.00 85.02  ? 384 LEU B CB  1 
ATOM 5525 C CG  . LEU B 2 384 ? 110.774 86.020  132.805 1.00 85.02  ? 384 LEU B CG  1 
ATOM 5526 C CD1 . LEU B 2 384 ? 109.908 87.266  132.817 1.00 85.02  ? 384 LEU B CD1 1 
ATOM 5527 C CD2 . LEU B 2 384 ? 111.633 85.967  131.556 1.00 85.02  ? 384 LEU B CD2 1 
ATOM 5528 N N   . VAL B 2 385 ? 108.936 83.955  135.242 1.00 87.11  ? 385 VAL B N   1 
ATOM 5529 C CA  . VAL B 2 385 ? 108.195 82.757  134.874 1.00 87.11  ? 385 VAL B CA  1 
ATOM 5530 C C   . VAL B 2 385 ? 107.692 82.918  133.448 1.00 87.11  ? 385 VAL B C   1 
ATOM 5531 O O   . VAL B 2 385 ? 107.036 83.911  133.118 1.00 87.11  ? 385 VAL B O   1 
ATOM 5532 C CB  . VAL B 2 385 ? 107.049 82.514  135.876 1.00 87.11  ? 385 VAL B CB  1 
ATOM 5533 C CG1 . VAL B 2 385 ? 105.959 81.618  135.284 1.00 87.11  ? 385 VAL B CG1 1 
ATOM 5534 C CG2 . VAL B 2 385 ? 107.590 81.924  137.168 1.00 87.11  ? 385 VAL B CG2 1 
ATOM 5535 N N   . VAL B 2 386 ? 108.021 81.958  132.590 1.00 96.55  ? 386 VAL B N   1 
ATOM 5536 C CA  . VAL B 2 386 ? 107.610 81.988  131.195 1.00 96.55  ? 386 VAL B CA  1 
ATOM 5537 C C   . VAL B 2 386 ? 106.497 80.965  130.979 1.00 96.55  ? 386 VAL B C   1 
ATOM 5538 O O   . VAL B 2 386 ? 106.301 80.043  131.771 1.00 96.55  ? 386 VAL B O   1 
ATOM 5539 C CB  . VAL B 2 386 ? 108.791 81.738  130.237 1.00 96.55  ? 386 VAL B CB  1 
ATOM 5540 C CG1 . VAL B 2 386 ? 109.862 82.796  130.431 1.00 96.55  ? 386 VAL B CG1 1 
ATOM 5541 C CG2 . VAL B 2 386 ? 109.368 80.351  130.453 1.00 96.55  ? 386 VAL B CG2 1 
ATOM 5542 N N   . SER B 2 387 ? 105.751 81.151  129.893 1.00 103.47 ? 387 SER B N   1 
ATOM 5543 C CA  . SER B 2 387 ? 104.694 80.221  129.522 1.00 103.47 ? 387 SER B CA  1 
ATOM 5544 C C   . SER B 2 387 ? 105.289 78.939  128.951 1.00 103.47 ? 387 SER B C   1 
ATOM 5545 O O   . SER B 2 387 ? 106.386 78.944  128.384 1.00 103.47 ? 387 SER B O   1 
ATOM 5546 C CB  . SER B 2 387 ? 103.745 80.877  128.519 1.00 103.47 ? 387 SER B CB  1 
ATOM 5547 O OG  . SER B 2 387 ? 104.311 80.916  127.226 1.00 103.47 ? 387 SER B OG  1 
ATOM 5548 N N   . LYS B 2 388 ? 104.554 77.833  129.102 1.00 112.92 ? 388 LYS B N   1 
ATOM 5549 C CA  . LYS B 2 388 ? 105.158 76.519  128.894 1.00 112.92 ? 388 LYS B CA  1 
ATOM 5550 C C   . LYS B 2 388 ? 104.691 75.863  127.598 1.00 112.92 ? 388 LYS B C   1 
ATOM 5551 O O   . LYS B 2 388 ? 105.406 75.023  127.039 1.00 112.92 ? 388 LYS B O   1 
ATOM 5552 C CB  . LYS B 2 388 ? 104.862 75.616  130.092 1.00 112.92 ? 388 LYS B CB  1 
ATOM 5553 C CG  . LYS B 2 388 ? 103.387 75.510  130.454 1.00 112.92 ? 388 LYS B CG  1 
ATOM 5554 C CD  . LYS B 2 388 ? 103.099 74.302  131.342 1.00 112.92 ? 388 LYS B CD  1 
ATOM 5555 C CE  . LYS B 2 388 ? 104.039 74.225  132.541 1.00 112.92 ? 388 LYS B CE  1 
ATOM 5556 N NZ  . LYS B 2 388 ? 103.943 75.434  133.404 1.00 112.92 ? 388 LYS B NZ  1 
ATOM 5557 N N   . GLN B 2 389 ? 103.494 76.212  127.111 1.00 115.17 ? 389 GLN B N   1 
ATOM 5558 C CA  . GLN B 2 389 ? 103.002 75.617  125.870 1.00 115.17 ? 389 GLN B CA  1 
ATOM 5559 C C   . GLN B 2 389 ? 103.756 76.155  124.661 1.00 115.17 ? 389 GLN B C   1 
ATOM 5560 O O   . GLN B 2 389 ? 104.422 75.392  123.952 1.00 115.17 ? 389 GLN B O   1 
ATOM 5561 C CB  . GLN B 2 389 ? 101.498 75.860  125.721 1.00 115.17 ? 389 GLN B CB  1 
ATOM 5562 C CG  . GLN B 2 389 ? 100.871 75.217  124.482 1.00 115.17 ? 389 GLN B CG  1 
ATOM 5563 C CD  . GLN B 2 389 ? 100.635 73.716  124.613 1.00 115.17 ? 389 GLN B CD  1 
ATOM 5564 O OE1 . GLN B 2 389 ? 100.839 73.123  125.674 1.00 115.17 ? 389 GLN B OE1 1 
ATOM 5565 N NE2 . GLN B 2 389 ? 100.205 73.095  123.521 1.00 115.17 ? 389 GLN B NE2 1 
ATOM 5566 N N   . ASN B 2 390 ? 103.666 77.457  124.411 1.00 107.73 ? 390 ASN B N   1 
ATOM 5567 C CA  . ASN B 2 390 ? 104.665 78.163  123.614 1.00 107.73 ? 390 ASN B CA  1 
ATOM 5568 C C   . ASN B 2 390 ? 105.540 78.989  124.552 1.00 107.73 ? 390 ASN B C   1 
ATOM 5569 O O   . ASN B 2 390 ? 105.038 79.570  125.529 1.00 107.73 ? 390 ASN B O   1 
ATOM 5570 C CB  . ASN B 2 390 ? 104.039 78.977  122.473 1.00 107.73 ? 390 ASN B CB  1 
ATOM 5571 C CG  . ASN B 2 390 ? 102.984 80.006  122.920 1.00 107.73 ? 390 ASN B CG  1 
ATOM 5572 O OD1 . ASN B 2 390 ? 102.712 80.214  124.097 1.00 107.73 ? 390 ASN B OD1 1 
ATOM 5573 N ND2 . ASN B 2 390 ? 102.390 80.666  121.933 1.00 107.73 ? 390 ASN B ND2 1 
ATOM 5574 N N   . PRO B 2 391 ? 106.857 78.950  124.387 1.00 107.03 ? 391 PRO B N   1 
ATOM 5575 C CA  . PRO B 2 391 ? 107.720 79.753  125.264 1.00 107.03 ? 391 PRO B CA  1 
ATOM 5576 C C   . PRO B 2 391 ? 107.637 81.248  124.977 1.00 107.03 ? 391 PRO B C   1 
ATOM 5577 O O   . PRO B 2 391 ? 107.472 82.055  125.897 1.00 107.03 ? 391 PRO B O   1 
ATOM 5578 C CB  . PRO B 2 391 ? 109.113 79.160  125.009 1.00 107.03 ? 391 PRO B CB  1 
ATOM 5579 C CG  . PRO B 2 391 ? 109.046 78.589  123.619 1.00 107.03 ? 391 PRO B CG  1 
ATOM 5580 C CD  . PRO B 2 391 ? 107.631 78.086  123.472 1.00 107.03 ? 391 PRO B CD  1 
ATOM 5581 N N   . PHE B 2 392 ? 107.717 81.607  123.700 1.00 103.39 ? 392 PHE B N   1 
ATOM 5582 C CA  . PHE B 2 392 ? 107.704 82.948  123.137 1.00 103.39 ? 392 PHE B CA  1 
ATOM 5583 C C   . PHE B 2 392 ? 107.470 82.818  121.633 1.00 103.39 ? 392 PHE B C   1 
ATOM 5584 O O   . PHE B 2 392 ? 108.063 81.932  121.003 1.00 103.39 ? 392 PHE B O   1 
ATOM 5585 C CB  . PHE B 2 392 ? 108.984 83.709  123.518 1.00 103.39 ? 392 PHE B CB  1 
ATOM 5586 C CG  . PHE B 2 392 ? 110.256 83.107  122.993 1.00 103.39 ? 392 PHE B CG  1 
ATOM 5587 C CD1 . PHE B 2 392 ? 110.928 82.158  123.755 1.00 103.39 ? 392 PHE B CD1 1 
ATOM 5588 C CD2 . PHE B 2 392 ? 110.819 83.525  121.793 1.00 103.39 ? 392 PHE B CD2 1 
ATOM 5589 C CE1 . PHE B 2 392 ? 112.103 81.597  123.315 1.00 103.39 ? 392 PHE B CE1 1 
ATOM 5590 C CE2 . PHE B 2 392 ? 112.003 82.962  121.347 1.00 103.39 ? 392 PHE B CE2 1 
ATOM 5591 C CZ  . PHE B 2 392 ? 112.643 82.002  122.117 1.00 103.39 ? 392 PHE B CZ  1 
ATOM 5592 N N   . PRO B 2 393 ? 106.565 83.618  121.053 1.00 102.06 ? 393 PRO B N   1 
ATOM 5593 C CA  . PRO B 2 393 ? 106.100 83.376  119.662 1.00 102.06 ? 393 PRO B CA  1 
ATOM 5594 C C   . PRO B 2 393 ? 107.184 83.611  118.624 1.00 102.06 ? 393 PRO B C   1 
ATOM 5595 O O   . PRO B 2 393 ? 108.097 84.425  118.831 1.00 102.06 ? 393 PRO B O   1 
ATOM 5596 C CB  . PRO B 2 393 ? 104.964 84.396  119.480 1.00 102.06 ? 393 PRO B CB  1 
ATOM 5597 C CG  . PRO B 2 393 ? 104.719 85.018  120.810 1.00 102.06 ? 393 PRO B CG  1 
ATOM 5598 C CD  . PRO B 2 393 ? 105.550 84.348  121.837 1.00 102.06 ? 393 PRO B CD  1 
ATOM 5599 N N   . PRO B 2 394 ? 107.122 82.904  117.495 1.00 108.80 ? 394 PRO B N   1 
ATOM 5600 C CA  . PRO B 2 394 ? 108.022 83.210  116.380 1.00 108.80 ? 394 PRO B CA  1 
ATOM 5601 C C   . PRO B 2 394 ? 107.509 84.382  115.560 1.00 108.80 ? 394 PRO B C   1 
ATOM 5602 O O   . PRO B 2 394 ? 106.436 84.937  115.809 1.00 108.80 ? 394 PRO B O   1 
ATOM 5603 C CB  . PRO B 2 394 ? 108.013 81.919  115.558 1.00 108.80 ? 394 PRO B CB  1 
ATOM 5604 C CG  . PRO B 2 394 ? 106.659 81.358  115.809 1.00 108.80 ? 394 PRO B CG  1 
ATOM 5605 C CD  . PRO B 2 394 ? 106.363 81.664  117.254 1.00 108.80 ? 394 PRO B CD  1 
ATOM 5606 N N   . LEU B 2 395 ? 108.297 84.749  114.556 1.00 108.11 ? 395 LEU B N   1 
ATOM 5607 C CA  . LEU B 2 395 ? 107.979 85.884  113.699 1.00 108.11 ? 395 LEU B CA  1 
ATOM 5608 C C   . LEU B 2 395 ? 107.942 85.459  112.235 1.00 108.11 ? 395 LEU B C   1 
ATOM 5609 O O   . LEU B 2 395 ? 107.091 85.906  111.468 1.00 108.11 ? 395 LEU B O   1 
ATOM 5610 C CB  . LEU B 2 395 ? 108.993 87.024  113.892 1.00 108.11 ? 395 LEU B CB  1 
ATOM 5611 C CG  . LEU B 2 395 ? 108.833 88.039  115.034 1.00 108.11 ? 395 LEU B CG  1 
ATOM 5612 C CD1 . LEU B 2 395 ? 109.088 87.450  116.407 1.00 108.11 ? 395 LEU B CD1 1 
ATOM 5613 C CD2 . LEU B 2 395 ? 109.751 89.231  114.814 1.00 108.11 ? 395 LEU B CD2 1 
ATOM 5614 N N   . ASP C 3 17  ? 124.304 107.859 94.812  1.00 118.79 ? 17  ASP C N   1 
ATOM 5615 C CA  . ASP C 3 17  ? 123.351 106.797 95.113  1.00 118.79 ? 17  ASP C CA  1 
ATOM 5616 C C   . ASP C 3 17  ? 121.952 107.171 94.636  1.00 118.79 ? 17  ASP C C   1 
ATOM 5617 O O   . ASP C 3 17  ? 121.014 107.245 95.430  1.00 118.79 ? 17  ASP C O   1 
ATOM 5618 C CB  . ASP C 3 17  ? 123.336 106.499 96.613  1.00 118.79 ? 17  ASP C CB  1 
ATOM 5619 N N   . GLU C 3 18  ? 121.818 107.404 93.334  1.00 113.93 ? 18  GLU C N   1 
ATOM 5620 C CA  . GLU C 3 18  ? 120.547 107.802 92.742  1.00 113.93 ? 18  GLU C CA  1 
ATOM 5621 C C   . GLU C 3 18  ? 119.970 106.632 91.953  1.00 113.93 ? 18  GLU C C   1 
ATOM 5622 O O   . GLU C 3 18  ? 120.700 105.943 91.232  1.00 113.93 ? 18  GLU C O   1 
ATOM 5623 C CB  . GLU C 3 18  ? 120.731 109.030 91.848  1.00 113.93 ? 18  GLU C CB  1 
ATOM 5624 C CG  . GLU C 3 18  ? 119.437 109.595 91.279  1.00 113.93 ? 18  GLU C CG  1 
ATOM 5625 C CD  . GLU C 3 18  ? 118.333 109.690 92.316  1.00 113.93 ? 18  GLU C CD  1 
ATOM 5626 O OE1 . GLU C 3 18  ? 117.264 109.081 92.101  1.00 113.93 ? 18  GLU C OE1 1 
ATOM 5627 O OE2 . GLU C 3 18  ? 118.520 110.393 93.333  1.00 113.93 ? 18  GLU C OE2 1 
ATOM 5628 N N   . PHE C 3 19  ? 118.663 106.408 92.098  1.00 111.72 ? 19  PHE C N   1 
ATOM 5629 C CA  . PHE C 3 19  ? 117.973 105.312 91.429  1.00 111.72 ? 19  PHE C CA  1 
ATOM 5630 C C   . PHE C 3 19  ? 117.842 105.660 89.948  1.00 111.72 ? 19  PHE C C   1 
ATOM 5631 O O   . PHE C 3 19  ? 117.011 106.491 89.568  1.00 111.72 ? 19  PHE C O   1 
ATOM 5632 C CB  . PHE C 3 19  ? 116.604 105.088 92.085  1.00 111.72 ? 19  PHE C CB  1 
ATOM 5633 C CG  . PHE C 3 19  ? 115.821 103.905 91.551  1.00 111.72 ? 19  PHE C CG  1 
ATOM 5634 C CD1 . PHE C 3 19  ? 114.447 103.860 91.738  1.00 111.72 ? 19  PHE C CD1 1 
ATOM 5635 C CD2 . PHE C 3 19  ? 116.450 102.795 90.986  1.00 111.72 ? 19  PHE C CD2 1 
ATOM 5636 C CE1 . PHE C 3 19  ? 113.700 102.784 91.290  1.00 111.72 ? 19  PHE C CE1 1 
ATOM 5637 C CE2 . PHE C 3 19  ? 115.708 101.715 90.535  1.00 111.72 ? 19  PHE C CE2 1 
ATOM 5638 C CZ  . PHE C 3 19  ? 114.332 101.708 90.694  1.00 111.72 ? 19  PHE C CZ  1 
ATOM 5639 N N   . GLU C 3 20  ? 118.662 105.027 89.114  1.00 126.64 ? 20  GLU C N   1 
ATOM 5640 C CA  . GLU C 3 20  ? 118.643 105.275 87.682  1.00 126.64 ? 20  GLU C CA  1 
ATOM 5641 C C   . GLU C 3 20  ? 117.446 104.565 87.047  1.00 126.64 ? 20  GLU C C   1 
ATOM 5642 O O   . GLU C 3 20  ? 117.009 103.504 87.502  1.00 126.64 ? 20  GLU C O   1 
ATOM 5643 C CB  . GLU C 3 20  ? 119.967 104.813 87.065  1.00 126.64 ? 20  GLU C CB  1 
ATOM 5644 C CG  . GLU C 3 20  ? 120.303 105.386 85.694  1.00 126.64 ? 20  GLU C CG  1 
ATOM 5645 C CD  . GLU C 3 20  ? 119.781 104.548 84.551  1.00 126.64 ? 20  GLU C CD  1 
ATOM 5646 O OE1 . GLU C 3 20  ? 119.058 105.097 83.694  1.00 126.64 ? 20  GLU C OE1 1 
ATOM 5647 O OE2 . GLU C 3 20  ? 120.088 103.338 84.509  1.00 126.64 ? 20  GLU C OE2 1 
ATOM 5648 N N   . GLU C 3 21  ? 116.909 105.171 85.989  1.00 128.57 ? 21  GLU C N   1 
ATOM 5649 C CA  . GLU C 3 21  ? 115.675 104.684 85.384  1.00 128.57 ? 21  GLU C CA  1 
ATOM 5650 C C   . GLU C 3 21  ? 115.915 103.429 84.549  1.00 128.57 ? 21  GLU C C   1 
ATOM 5651 O O   . GLU C 3 21  ? 117.052 103.041 84.274  1.00 128.57 ? 21  GLU C O   1 
ATOM 5652 C CB  . GLU C 3 21  ? 115.037 105.768 84.514  1.00 128.57 ? 21  GLU C CB  1 
ATOM 5653 C CG  . GLU C 3 21  ? 115.787 106.059 83.227  1.00 128.57 ? 21  GLU C CG  1 
ATOM 5654 C CD  . GLU C 3 21  ? 116.716 107.249 83.349  1.00 128.57 ? 21  GLU C CD  1 
ATOM 5655 O OE1 . GLU C 3 21  ? 116.994 107.677 84.489  1.00 128.57 ? 21  GLU C OE1 1 
ATOM 5656 O OE2 . GLU C 3 21  ? 117.167 107.761 82.303  1.00 128.57 ? 21  GLU C OE2 1 
ATOM 5657 N N   . PHE C 3 22  ? 114.824 102.793 84.148  1.00 119.96 ? 22  PHE C N   1 
ATOM 5658 C CA  . PHE C 3 22  ? 114.939 101.507 83.475  1.00 119.96 ? 22  PHE C CA  1 
ATOM 5659 C C   . PHE C 3 22  ? 115.113 101.704 81.969  1.00 119.96 ? 22  PHE C C   1 
ATOM 5660 O O   . PHE C 3 22  ? 114.600 102.677 81.410  1.00 119.96 ? 22  PHE C O   1 
ATOM 5661 C CB  . PHE C 3 22  ? 113.707 100.656 83.757  1.00 119.96 ? 22  PHE C CB  1 
ATOM 5662 C CG  . PHE C 3 22  ? 113.605 100.214 85.186  1.00 119.96 ? 22  PHE C CG  1 
ATOM 5663 C CD1 . PHE C 3 22  ? 114.307 99.105  85.632  1.00 119.96 ? 22  PHE C CD1 1 
ATOM 5664 C CD2 . PHE C 3 22  ? 112.817 100.918 86.086  1.00 119.96 ? 22  PHE C CD2 1 
ATOM 5665 C CE1 . PHE C 3 22  ? 114.222 98.699  86.952  1.00 119.96 ? 22  PHE C CE1 1 
ATOM 5666 C CE2 . PHE C 3 22  ? 112.724 100.517 87.409  1.00 119.96 ? 22  PHE C CE2 1 
ATOM 5667 C CZ  . PHE C 3 22  ? 113.427 99.406  87.842  1.00 119.96 ? 22  PHE C CZ  1 
ATOM 5668 N N   . PRO C 3 23  ? 115.860 100.813 81.300  1.00 126.02 ? 23  PRO C N   1 
ATOM 5669 C CA  . PRO C 3 23  ? 116.012 100.934 79.836  1.00 126.02 ? 23  PRO C CA  1 
ATOM 5670 C C   . PRO C 3 23  ? 114.734 100.667 79.054  1.00 126.02 ? 23  PRO C C   1 
ATOM 5671 O O   . PRO C 3 23  ? 114.499 101.302 78.019  1.00 126.02 ? 23  PRO C O   1 
ATOM 5672 C CB  . PRO C 3 23  ? 117.097 99.895  79.521  1.00 126.02 ? 23  PRO C CB  1 
ATOM 5673 C CG  . PRO C 3 23  ? 117.858 99.739  80.787  1.00 126.02 ? 23  PRO C CG  1 
ATOM 5674 C CD  . PRO C 3 23  ? 116.837 99.873  81.876  1.00 126.02 ? 23  PRO C CD  1 
ATOM 5675 N N   . ALA C 3 24  ? 113.903 99.741  79.519  1.00 123.28 ? 24  ALA C N   1 
ATOM 5676 C CA  . ALA C 3 24  ? 112.667 99.383  78.842  1.00 123.28 ? 24  ALA C CA  1 
ATOM 5677 C C   . ALA C 3 24  ? 111.473 99.838  79.670  1.00 123.28 ? 24  ALA C C   1 
ATOM 5678 O O   . ALA C 3 24  ? 111.470 99.757  80.901  1.00 123.28 ? 24  ALA C O   1 
ATOM 5679 C CB  . ALA C 3 24  ? 112.594 97.872  78.585  1.00 123.28 ? 24  ALA C CB  1 
ATOM 5680 N N   . GLU C 3 25  ? 110.450 100.331 78.972  1.00 128.21 ? 25  GLU C N   1 
ATOM 5681 C CA  . GLU C 3 25  ? 109.249 100.805 79.649  1.00 128.21 ? 25  GLU C CA  1 
ATOM 5682 C C   . GLU C 3 25  ? 108.371 99.651  80.119  1.00 128.21 ? 25  GLU C C   1 
ATOM 5683 O O   . GLU C 3 25  ? 107.783 99.720  81.203  1.00 128.21 ? 25  GLU C O   1 
ATOM 5684 C CB  . GLU C 3 25  ? 108.458 101.734 78.729  1.00 128.21 ? 25  GLU C CB  1 
ATOM 5685 C CG  . GLU C 3 25  ? 109.007 103.148 78.658  1.00 128.21 ? 25  GLU C CG  1 
ATOM 5686 C CD  . GLU C 3 25  ? 108.489 104.032 79.776  1.00 128.21 ? 25  GLU C CD  1 
ATOM 5687 O OE1 . GLU C 3 25  ? 109.033 105.141 79.959  1.00 128.21 ? 25  GLU C OE1 1 
ATOM 5688 O OE2 . GLU C 3 25  ? 107.537 103.619 80.471  1.00 128.21 ? 25  GLU C OE2 1 
ATOM 5689 N N   . ASP C 3 26  ? 108.277 98.585  79.327  1.00 131.34 ? 26  ASP C N   1 
ATOM 5690 C CA  . ASP C 3 26  ? 107.406 97.461  79.632  1.00 131.34 ? 26  ASP C CA  1 
ATOM 5691 C C   . ASP C 3 26  ? 108.179 96.154  79.510  1.00 131.34 ? 26  ASP C C   1 
ATOM 5692 O O   . ASP C 3 26  ? 109.115 96.030  78.716  1.00 131.34 ? 26  ASP C O   1 
ATOM 5693 C CB  . ASP C 3 26  ? 106.183 97.430  78.704  1.00 131.34 ? 26  ASP C CB  1 
ATOM 5694 C CG  . ASP C 3 26  ? 105.223 98.575  78.963  1.00 131.34 ? 26  ASP C CG  1 
ATOM 5695 O OD1 . ASP C 3 26  ? 105.152 99.048  80.116  1.00 131.34 ? 26  ASP C OD1 1 
ATOM 5696 O OD2 . ASP C 3 26  ? 104.539 99.004  78.010  1.00 131.34 ? 26  ASP C OD2 1 
ATOM 5697 N N   . TRP C 3 27  ? 107.768 95.175  80.312  1.00 131.91 ? 27  TRP C N   1 
ATOM 5698 C CA  . TRP C 3 27  ? 108.345 93.838  80.263  1.00 131.91 ? 27  TRP C CA  1 
ATOM 5699 C C   . TRP C 3 27  ? 107.288 92.834  80.702  1.00 131.91 ? 27  TRP C C   1 
ATOM 5700 O O   . TRP C 3 27  ? 106.293 93.187  81.340  1.00 131.91 ? 27  TRP C O   1 
ATOM 5701 C CB  . TRP C 3 27  ? 109.611 93.737  81.124  1.00 131.91 ? 27  TRP C CB  1 
ATOM 5702 C CG  . TRP C 3 27  ? 109.403 94.031  82.580  1.00 131.91 ? 27  TRP C CG  1 
ATOM 5703 C CD1 . TRP C 3 27  ? 109.038 93.148  83.555  1.00 131.91 ? 27  TRP C CD1 1 
ATOM 5704 C CD2 . TRP C 3 27  ? 109.580 95.294  83.230  1.00 131.91 ? 27  TRP C CD2 1 
ATOM 5705 N NE1 . TRP C 3 27  ? 108.960 93.788  84.768  1.00 131.91 ? 27  TRP C NE1 1 
ATOM 5706 C CE2 . TRP C 3 27  ? 109.290 95.106  84.596  1.00 131.91 ? 27  TRP C CE2 1 
ATOM 5707 C CE3 . TRP C 3 27  ? 109.951 96.568  82.788  1.00 131.91 ? 27  TRP C CE3 1 
ATOM 5708 C CZ2 . TRP C 3 27  ? 109.358 96.143  85.523  1.00 131.91 ? 27  TRP C CZ2 1 
ATOM 5709 C CZ3 . TRP C 3 27  ? 110.018 97.597  83.710  1.00 131.91 ? 27  TRP C CZ3 1 
ATOM 5710 C CH2 . TRP C 3 27  ? 109.724 97.378  85.061  1.00 131.91 ? 27  TRP C CH2 1 
ATOM 5711 N N   . ALA C 3 28  ? 107.520 91.572  80.350  1.00 136.58 ? 28  ALA C N   1 
ATOM 5712 C CA  . ALA C 3 28  ? 106.580 90.500  80.635  1.00 136.58 ? 28  ALA C CA  1 
ATOM 5713 C C   . ALA C 3 28  ? 106.837 89.939  82.033  1.00 136.58 ? 28  ALA C C   1 
ATOM 5714 O O   . ALA C 3 28  ? 107.746 90.373  82.746  1.00 136.58 ? 28  ALA C O   1 
ATOM 5715 C CB  . ALA C 3 28  ? 106.675 89.419  79.560  1.00 136.58 ? 28  ALA C CB  1 
ATOM 5716 N N   . GLY C 3 29  ? 106.029 88.957  82.439  1.00 135.64 ? 29  GLY C N   1 
ATOM 5717 C CA  . GLY C 3 29  ? 106.172 88.398  83.774  1.00 135.64 ? 29  GLY C CA  1 
ATOM 5718 C C   . GLY C 3 29  ? 107.344 87.443  83.898  1.00 135.64 ? 29  GLY C C   1 
ATOM 5719 O O   . GLY C 3 29  ? 107.815 87.167  85.005  1.00 135.64 ? 29  GLY C O   1 
ATOM 5720 N N   . LEU C 3 30  ? 107.827 86.918  82.770  1.00 138.94 ? 30  LEU C N   1 
ATOM 5721 C CA  . LEU C 3 30  ? 108.971 86.015  82.803  1.00 138.94 ? 30  LEU C CA  1 
ATOM 5722 C C   . LEU C 3 30  ? 110.296 86.752  82.649  1.00 138.94 ? 30  LEU C C   1 
ATOM 5723 O O   . LEU C 3 30  ? 111.351 86.108  82.649  1.00 138.94 ? 30  LEU C O   1 
ATOM 5724 C CB  . LEU C 3 30  ? 108.809 84.929  81.727  1.00 138.94 ? 30  LEU C CB  1 
ATOM 5725 C CG  . LEU C 3 30  ? 108.660 85.231  80.225  1.00 138.94 ? 30  LEU C CG  1 
ATOM 5726 C CD1 . LEU C 3 30  ? 109.985 85.340  79.460  1.00 138.94 ? 30  LEU C CD1 1 
ATOM 5727 C CD2 . LEU C 3 30  ? 107.755 84.190  79.574  1.00 138.94 ? 30  LEU C CD2 1 
ATOM 5728 N N   . ASP C 3 31  ? 110.265 88.079  82.508  1.00 138.64 ? 31  ASP C N   1 
ATOM 5729 C CA  . ASP C 3 31  ? 111.502 88.829  82.314  1.00 138.64 ? 31  ASP C CA  1 
ATOM 5730 C C   . ASP C 3 31  ? 112.271 88.985  83.621  1.00 138.64 ? 31  ASP C C   1 
ATOM 5731 O O   . ASP C 3 31  ? 113.508 88.991  83.621  1.00 138.64 ? 31  ASP C O   1 
ATOM 5732 C CB  . ASP C 3 31  ? 111.195 90.195  81.700  1.00 138.64 ? 31  ASP C CB  1 
ATOM 5733 C CG  . ASP C 3 31  ? 112.315 90.698  80.809  1.00 138.64 ? 31  ASP C CG  1 
ATOM 5734 O OD1 . ASP C 3 31  ? 113.393 90.068  80.795  1.00 138.64 ? 31  ASP C OD1 1 
ATOM 5735 O OD2 . ASP C 3 31  ? 112.115 91.719  80.119  1.00 138.64 ? 31  ASP C OD2 1 
ATOM 5736 N N   . GLU C 3 32  ? 111.564 89.114  84.741  1.00 141.77 ? 32  GLU C N   1 
ATOM 5737 C CA  . GLU C 3 32  ? 112.230 89.237  86.032  1.00 141.77 ? 32  GLU C CA  1 
ATOM 5738 C C   . GLU C 3 32  ? 112.638 87.862  86.549  1.00 141.77 ? 32  GLU C C   1 
ATOM 5739 O O   . GLU C 3 32  ? 112.062 86.841  86.158  1.00 141.77 ? 32  GLU C O   1 
ATOM 5740 C CB  . GLU C 3 32  ? 111.322 89.938  87.044  1.00 141.77 ? 32  GLU C CB  1 
ATOM 5741 C CG  . GLU C 3 32  ? 110.027 89.206  87.361  1.00 141.77 ? 32  GLU C CG  1 
ATOM 5742 C CD  . GLU C 3 32  ? 108.846 89.741  86.578  1.00 141.77 ? 32  GLU C CD  1 
ATOM 5743 O OE1 . GLU C 3 32  ? 109.066 90.465  85.585  1.00 141.77 ? 32  GLU C OE1 1 
ATOM 5744 O OE2 . GLU C 3 32  ? 107.695 89.438  86.956  1.00 141.77 ? 32  GLU C OE2 1 
ATOM 5745 N N   . ASP C 3 33  ? 113.639 87.836  87.424  1.00 144.78 ? 33  ASP C N   1 
ATOM 5746 C CA  . ASP C 3 33  ? 114.153 86.602  87.997  1.00 144.78 ? 33  ASP C CA  1 
ATOM 5747 C C   . ASP C 3 33  ? 114.315 86.731  89.508  1.00 144.78 ? 33  ASP C C   1 
ATOM 5748 O O   . ASP C 3 33  ? 114.477 87.832  90.042  1.00 144.78 ? 33  ASP C O   1 
ATOM 5749 C CB  . ASP C 3 33  ? 115.486 86.194  87.336  1.00 144.78 ? 33  ASP C CB  1 
ATOM 5750 C CG  . ASP C 3 33  ? 116.537 87.302  87.361  1.00 144.78 ? 33  ASP C CG  1 
ATOM 5751 O OD1 . ASP C 3 33  ? 116.239 88.440  87.783  1.00 144.78 ? 33  ASP C OD1 1 
ATOM 5752 O OD2 . ASP C 3 33  ? 117.683 87.025  86.948  1.00 144.78 ? 33  ASP C OD2 1 
ATOM 5753 N N   . GLU C 3 34  ? 114.258 85.591  90.192  1.00 153.97 ? 34  GLU C N   1 
ATOM 5754 C CA  . GLU C 3 34  ? 114.406 85.524  91.639  1.00 153.97 ? 34  GLU C CA  1 
ATOM 5755 C C   . GLU C 3 34  ? 115.230 84.293  92.000  1.00 153.97 ? 34  GLU C C   1 
ATOM 5756 O O   . GLU C 3 34  ? 115.574 83.474  91.142  1.00 153.97 ? 34  GLU C O   1 
ATOM 5757 C CB  . GLU C 3 34  ? 113.040 85.499  92.345  1.00 153.97 ? 34  GLU C CB  1 
ATOM 5758 C CG  . GLU C 3 34  ? 112.279 84.169  92.276  1.00 153.97 ? 34  GLU C CG  1 
ATOM 5759 C CD  . GLU C 3 34  ? 111.628 83.906  90.928  1.00 153.97 ? 34  GLU C CD  1 
ATOM 5760 O OE1 . GLU C 3 34  ? 111.475 84.861  90.137  1.00 153.97 ? 34  GLU C OE1 1 
ATOM 5761 O OE2 . GLU C 3 34  ? 111.270 82.740  90.661  1.00 153.97 ? 34  GLU C OE2 1 
ATOM 5762 N N   . ASP C 3 35  ? 115.553 84.166  93.290  1.00 157.02 ? 35  ASP C N   1 
ATOM 5763 C CA  . ASP C 3 35  ? 116.315 83.029  93.790  1.00 157.02 ? 35  ASP C CA  1 
ATOM 5764 C C   . ASP C 3 35  ? 115.468 82.091  94.644  1.00 157.02 ? 35  ASP C C   1 
ATOM 5765 O O   . ASP C 3 35  ? 116.036 81.304  95.415  1.00 157.02 ? 35  ASP C O   1 
ATOM 5766 C CB  . ASP C 3 35  ? 117.532 83.508  94.592  1.00 157.02 ? 35  ASP C CB  1 
ATOM 5767 C CG  . ASP C 3 35  ? 118.769 82.666  94.339  1.00 157.02 ? 35  ASP C CG  1 
ATOM 5768 O OD1 . ASP C 3 35  ? 118.625 81.466  94.022  1.00 157.02 ? 35  ASP C OD1 1 
ATOM 5769 O OD2 . ASP C 3 35  ? 119.888 83.205  94.458  1.00 157.02 ? 35  ASP C OD2 1 
ATOM 5770 N N   . ALA C 3 36  ? 114.134 82.204  94.561  1.00 152.14 ? 36  ALA C N   1 
ATOM 5771 C CA  . ALA C 3 36  ? 113.127 81.325  95.162  1.00 152.14 ? 36  ALA C CA  1 
ATOM 5772 C C   . ALA C 3 36  ? 113.201 81.296  96.685  1.00 152.14 ? 36  ALA C C   1 
ATOM 5773 O O   . ALA C 3 36  ? 112.355 81.889  97.362  1.00 152.14 ? 36  ALA C O   1 
ATOM 5774 C CB  . ALA C 3 36  ? 113.221 79.901  94.596  1.00 152.14 ? 36  ALA C CB  1 
ATOM 5775 N N   . HIS C 3 37  ? 114.204 80.614  97.233  1.00 141.05 ? 37  HIS C N   1 
ATOM 5776 C CA  . HIS C 3 37  ? 114.375 80.498  98.681  1.00 141.05 ? 37  HIS C CA  1 
ATOM 5777 C C   . HIS C 3 37  ? 115.490 81.450  99.132  1.00 141.05 ? 37  HIS C C   1 
ATOM 5778 O O   . HIS C 3 37  ? 116.678 81.231  98.886  1.00 141.05 ? 37  HIS C O   1 
ATOM 5779 C CB  . HIS C 3 37  ? 114.564 79.026  99.076  1.00 141.05 ? 37  HIS C CB  1 
ATOM 5780 C CG  . HIS C 3 37  ? 115.803 78.374  98.537  1.00 141.05 ? 37  HIS C CG  1 
ATOM 5781 N ND1 . HIS C 3 37  ? 115.887 77.887  97.250  1.00 141.05 ? 37  HIS C ND1 1 
ATOM 5782 C CD2 . HIS C 3 37  ? 117.001 78.117  99.114  1.00 141.05 ? 37  HIS C CD2 1 
ATOM 5783 C CE1 . HIS C 3 37  ? 117.086 77.368  97.055  1.00 141.05 ? 37  HIS C CE1 1 
ATOM 5784 N NE2 . HIS C 3 37  ? 117.781 77.495  98.171  1.00 141.05 ? 37  HIS C NE2 1 
ATOM 5785 N N   . VAL C 3 38  ? 115.082 82.577  99.715  1.00 123.03 ? 38  VAL C N   1 
ATOM 5786 C CA  . VAL C 3 38  ? 116.013 83.551  100.275 1.00 123.03 ? 38  VAL C CA  1 
ATOM 5787 C C   . VAL C 3 38  ? 115.630 83.831  101.719 1.00 123.03 ? 38  VAL C C   1 
ATOM 5788 O O   . VAL C 3 38  ? 116.428 83.627  102.640 1.00 123.03 ? 38  VAL C O   1 
ATOM 5789 C CB  . VAL C 3 38  ? 116.036 84.864  99.468  1.00 123.03 ? 38  VAL C CB  1 
ATOM 5790 C CG1 . VAL C 3 38  ? 116.935 85.876  100.157 1.00 123.03 ? 38  VAL C CG1 1 
ATOM 5791 C CG2 . VAL C 3 38  ? 116.516 84.627  98.045  1.00 123.03 ? 38  VAL C CG2 1 
ATOM 5792 N N   . TRP C 3 39  ? 114.405 84.307  101.919 1.00 117.68 ? 39  TRP C N   1 
ATOM 5793 C CA  . TRP C 3 39  ? 113.936 84.770  103.222 1.00 117.68 ? 39  TRP C CA  1 
ATOM 5794 C C   . TRP C 3 39  ? 113.304 83.584  103.937 1.00 117.68 ? 39  TRP C C   1 
ATOM 5795 O O   . TRP C 3 39  ? 112.089 83.382  103.903 1.00 117.68 ? 39  TRP C O   1 
ATOM 5796 C CB  . TRP C 3 39  ? 112.958 85.922  103.044 1.00 117.68 ? 39  TRP C CB  1 
ATOM 5797 C CG  . TRP C 3 39  ? 113.335 86.824  101.904 1.00 117.68 ? 39  TRP C CG  1 
ATOM 5798 C CD1 . TRP C 3 39  ? 112.765 86.858  100.665 1.00 117.68 ? 39  TRP C CD1 1 
ATOM 5799 C CD2 . TRP C 3 39  ? 114.374 87.810  101.894 1.00 117.68 ? 39  TRP C CD2 1 
ATOM 5800 N NE1 . TRP C 3 39  ? 113.379 87.808  99.887  1.00 117.68 ? 39  TRP C NE1 1 
ATOM 5801 C CE2 . TRP C 3 39  ? 114.369 88.409  100.619 1.00 117.68 ? 39  TRP C CE2 1 
ATOM 5802 C CE3 . TRP C 3 39  ? 115.298 88.254  102.844 1.00 117.68 ? 39  TRP C CE3 1 
ATOM 5803 C CZ2 . TRP C 3 39  ? 115.257 89.423  100.267 1.00 117.68 ? 39  TRP C CZ2 1 
ATOM 5804 C CZ3 . TRP C 3 39  ? 116.179 89.261  102.493 1.00 117.68 ? 39  TRP C CZ3 1 
ATOM 5805 C CH2 . TRP C 3 39  ? 116.153 89.833  101.215 1.00 117.68 ? 39  TRP C CH2 1 
ATOM 5806 N N   . GLU C 3 40  ? 114.141 82.788  104.598 1.00 123.56 ? 40  GLU C N   1 
ATOM 5807 C CA  . GLU C 3 40  ? 113.715 81.540  105.210 1.00 123.56 ? 40  GLU C CA  1 
ATOM 5808 C C   . GLU C 3 40  ? 113.643 81.695  106.723 1.00 123.56 ? 40  GLU C C   1 
ATOM 5809 O O   . GLU C 3 40  ? 114.240 82.609  107.300 1.00 123.56 ? 40  GLU C O   1 
ATOM 5810 C CB  . GLU C 3 40  ? 114.674 80.385  104.837 1.00 123.56 ? 40  GLU C CB  1 
ATOM 5811 C CG  . GLU C 3 40  ? 115.842 80.121  105.808 1.00 123.56 ? 40  GLU C CG  1 
ATOM 5812 C CD  . GLU C 3 40  ? 117.082 80.976  105.560 1.00 123.56 ? 40  GLU C CD  1 
ATOM 5813 O OE1 . GLU C 3 40  ? 118.192 80.495  105.868 1.00 123.56 ? 40  GLU C OE1 1 
ATOM 5814 O OE2 . GLU C 3 40  ? 116.965 82.119  105.075 1.00 123.56 ? 40  GLU C OE2 1 
ATOM 5815 N N   . ASP C 3 41  ? 112.883 80.804  107.362 1.00 129.54 ? 41  ASP C N   1 
ATOM 5816 C CA  . ASP C 3 41  ? 112.889 80.666  108.819 1.00 129.54 ? 41  ASP C CA  1 
ATOM 5817 C C   . ASP C 3 41  ? 113.242 79.232  109.245 1.00 129.54 ? 41  ASP C C   1 
ATOM 5818 O O   . ASP C 3 41  ? 112.415 78.421  109.671 1.00 129.54 ? 41  ASP C O   1 
ATOM 5819 C CB  . ASP C 3 41  ? 111.549 81.220  109.406 1.00 129.54 ? 41  ASP C CB  1 
ATOM 5820 C CG  . ASP C 3 41  ? 110.285 80.484  108.915 1.00 129.54 ? 41  ASP C CG  1 
ATOM 5821 O OD1 . ASP C 3 41  ? 110.362 79.560  108.076 1.00 129.54 ? 41  ASP C OD1 1 
ATOM 5822 O OD2 . ASP C 3 41  ? 109.189 80.846  109.393 1.00 129.54 ? 41  ASP C OD2 1 
ATOM 5823 N N   . ASN C 3 42  ? 114.546 78.940  109.201 1.00 123.48 ? 42  ASN C N   1 
ATOM 5824 C CA  . ASN C 3 42  ? 115.100 77.703  109.733 1.00 123.48 ? 42  ASN C CA  1 
ATOM 5825 C C   . ASN C 3 42  ? 115.961 77.947  110.963 1.00 123.48 ? 42  ASN C C   1 
ATOM 5826 O O   . ASN C 3 42  ? 116.330 76.985  111.645 1.00 123.48 ? 42  ASN C O   1 
ATOM 5827 C CB  . ASN C 3 42  ? 115.950 76.965  108.679 1.00 123.48 ? 42  ASN C CB  1 
ATOM 5828 C CG  . ASN C 3 42  ? 115.191 76.652  107.393 1.00 123.48 ? 42  ASN C CG  1 
ATOM 5829 O OD1 . ASN C 3 42  ? 114.055 77.074  107.193 1.00 123.48 ? 42  ASN C OD1 1 
ATOM 5830 N ND2 . ASN C 3 42  ? 115.832 75.893  106.510 1.00 123.48 ? 42  ASN C ND2 1 
ATOM 5831 N N   . TRP C 3 43  ? 116.283 79.203  111.266 1.00 119.25 ? 43  TRP C N   1 
ATOM 5832 C CA  . TRP C 3 43  ? 117.182 79.570  112.350 1.00 119.25 ? 43  TRP C CA  1 
ATOM 5833 C C   . TRP C 3 43  ? 116.530 79.529  113.725 1.00 119.25 ? 43  TRP C C   1 
ATOM 5834 O O   . TRP C 3 43  ? 117.246 79.596  114.730 1.00 119.25 ? 43  TRP C O   1 
ATOM 5835 C CB  . TRP C 3 43  ? 117.793 80.954  112.041 1.00 119.25 ? 43  TRP C CB  1 
ATOM 5836 C CG  . TRP C 3 43  ? 116.851 82.155  112.072 1.00 119.25 ? 43  TRP C CG  1 
ATOM 5837 C CD1 . TRP C 3 43  ? 116.385 82.830  110.979 1.00 119.25 ? 43  TRP C CD1 1 
ATOM 5838 C CD2 . TRP C 3 43  ? 116.399 82.906  113.218 1.00 119.25 ? 43  TRP C CD2 1 
ATOM 5839 N NE1 . TRP C 3 43  ? 115.603 83.888  111.366 1.00 119.25 ? 43  TRP C NE1 1 
ATOM 5840 C CE2 . TRP C 3 43  ? 115.604 83.965  112.732 1.00 119.25 ? 43  TRP C CE2 1 
ATOM 5841 C CE3 . TRP C 3 43  ? 116.564 82.772  114.601 1.00 119.25 ? 43  TRP C CE3 1 
ATOM 5842 C CZ2 . TRP C 3 43  ? 114.973 84.875  113.578 1.00 119.25 ? 43  TRP C CZ2 1 
ATOM 5843 C CZ3 . TRP C 3 43  ? 115.931 83.672  115.436 1.00 119.25 ? 43  TRP C CZ3 1 
ATOM 5844 C CH2 . TRP C 3 43  ? 115.149 84.711  114.924 1.00 119.25 ? 43  TRP C CH2 1 
ATOM 5845 N N   . ASP C 3 44  ? 115.205 79.411  113.806 1.00 130.67 ? 44  ASP C N   1 
ATOM 5846 C CA  . ASP C 3 44  ? 114.516 79.342  115.098 1.00 130.67 ? 44  ASP C CA  1 
ATOM 5847 C C   . ASP C 3 44  ? 114.393 77.880  115.535 1.00 130.67 ? 44  ASP C C   1 
ATOM 5848 O O   . ASP C 3 44  ? 113.307 77.306  115.640 1.00 130.67 ? 44  ASP C O   1 
ATOM 5849 C CB  . ASP C 3 44  ? 113.156 80.023  115.013 1.00 130.67 ? 44  ASP C CB  1 
ATOM 5850 C CG  . ASP C 3 44  ? 112.625 80.442  116.374 1.00 130.67 ? 44  ASP C CG  1 
ATOM 5851 O OD1 . ASP C 3 44  ? 112.209 79.565  117.161 1.00 130.67 ? 44  ASP C OD1 1 
ATOM 5852 O OD2 . ASP C 3 44  ? 112.632 81.657  116.662 1.00 130.67 ? 44  ASP C OD2 1 
ATOM 5853 N N   . ASP C 3 45  ? 115.549 77.280  115.797 1.00 136.95 ? 45  ASP C N   1 
ATOM 5854 C CA  . ASP C 3 45  ? 115.652 75.878  116.166 1.00 136.95 ? 45  ASP C CA  1 
ATOM 5855 C C   . ASP C 3 45  ? 116.440 75.721  117.468 1.00 136.95 ? 45  ASP C C   1 
ATOM 5856 O O   . ASP C 3 45  ? 116.801 76.700  118.126 1.00 136.95 ? 45  ASP C O   1 
ATOM 5857 C CB  . ASP C 3 45  ? 116.222 75.067  114.988 1.00 136.95 ? 45  ASP C CB  1 
ATOM 5858 C CG  . ASP C 3 45  ? 117.643 75.482  114.570 1.00 136.95 ? 45  ASP C CG  1 
ATOM 5859 O OD1 . ASP C 3 45  ? 118.243 76.428  115.126 1.00 136.95 ? 45  ASP C OD1 1 
ATOM 5860 O OD2 . ASP C 3 45  ? 118.161 74.849  113.628 1.00 136.95 ? 45  ASP C OD2 1 
ATOM 5861 N N   . ASP C 3 46  ? 116.715 74.471  117.831 1.00 142.35 ? 46  ASP C N   1 
ATOM 5862 C CA  . ASP C 3 46  ? 117.282 74.136  119.133 1.00 142.35 ? 46  ASP C CA  1 
ATOM 5863 C C   . ASP C 3 46  ? 118.727 73.647  119.048 1.00 142.35 ? 46  ASP C C   1 
ATOM 5864 O O   . ASP C 3 46  ? 119.116 72.696  119.729 1.00 142.35 ? 46  ASP C O   1 
ATOM 5865 C CB  . ASP C 3 46  ? 116.407 73.105  119.841 1.00 142.35 ? 46  ASP C CB  1 
ATOM 5866 C CG  . ASP C 3 46  ? 114.974 73.577  120.006 1.00 142.35 ? 46  ASP C CG  1 
ATOM 5867 O OD1 . ASP C 3 46  ? 114.294 73.802  118.983 1.00 142.35 ? 46  ASP C OD1 1 
ATOM 5868 O OD2 . ASP C 3 46  ? 114.527 73.718  121.163 1.00 142.35 ? 46  ASP C OD2 1 
ATOM 5869 N N   . ASN C 3 47  ? 119.543 74.289  118.212 1.00 140.49 ? 47  ASN C N   1 
ATOM 5870 C CA  . ASN C 3 47  ? 120.969 73.981  118.166 1.00 140.49 ? 47  ASN C CA  1 
ATOM 5871 C C   . ASN C 3 47  ? 121.735 74.691  119.277 1.00 140.49 ? 47  ASN C C   1 
ATOM 5872 O O   . ASN C 3 47  ? 121.870 75.918  119.265 1.00 140.49 ? 47  ASN C O   1 
ATOM 5873 C CB  . ASN C 3 47  ? 121.551 74.343  116.801 1.00 140.49 ? 47  ASN C CB  1 
ATOM 5874 C CG  . ASN C 3 47  ? 121.190 73.329  115.737 1.00 140.49 ? 47  ASN C CG  1 
ATOM 5875 O OD1 . ASN C 3 47  ? 120.505 73.642  114.774 1.00 140.49 ? 47  ASN C OD1 1 
ATOM 5876 N ND2 . ASN C 3 47  ? 121.665 72.102  115.907 1.00 140.49 ? 47  ASN C ND2 1 
ATOM 5877 N N   . VAL C 3 48  ? 122.238 73.918  120.242 1.00 133.04 ? 48  VAL C N   1 
ATOM 5878 C CA  . VAL C 3 48  ? 122.949 74.495  121.378 1.00 133.04 ? 48  VAL C CA  1 
ATOM 5879 C C   . VAL C 3 48  ? 124.457 74.454  121.129 1.00 133.04 ? 48  VAL C C   1 
ATOM 5880 O O   . VAL C 3 48  ? 125.203 75.346  121.552 1.00 133.04 ? 48  VAL C O   1 
ATOM 5881 C CB  . VAL C 3 48  ? 122.544 73.750  122.669 1.00 133.04 ? 48  VAL C CB  1 
ATOM 5882 C CG1 . VAL C 3 48  ? 123.233 74.305  123.917 1.00 133.04 ? 48  VAL C CG1 1 
ATOM 5883 C CG2 . VAL C 3 48  ? 121.030 73.768  122.836 1.00 133.04 ? 48  VAL C CG2 1 
ATOM 5884 N N   . GLU C 3 49  ? 124.913 73.472  120.349 1.00 129.51 ? 49  GLU C N   1 
ATOM 5885 C CA  . GLU C 3 49  ? 126.325 73.113  120.233 1.00 129.51 ? 49  GLU C CA  1 
ATOM 5886 C C   . GLU C 3 49  ? 127.151 74.050  119.337 1.00 129.51 ? 49  GLU C C   1 
ATOM 5887 O O   . GLU C 3 49  ? 128.274 73.682  118.968 1.00 129.51 ? 49  GLU C O   1 
ATOM 5888 C CB  . GLU C 3 49  ? 126.452 71.664  119.729 1.00 129.51 ? 49  GLU C CB  1 
ATOM 5889 C CG  . GLU C 3 49  ? 126.084 71.332  118.245 1.00 129.51 ? 49  GLU C CG  1 
ATOM 5890 C CD  . GLU C 3 49  ? 124.614 71.504  117.808 1.00 129.51 ? 49  GLU C CD  1 
ATOM 5891 O OE1 . GLU C 3 49  ? 124.271 70.894  116.773 1.00 129.51 ? 49  GLU C OE1 1 
ATOM 5892 O OE2 . GLU C 3 49  ? 123.790 72.186  118.457 1.00 129.51 ? 49  GLU C OE2 1 
ATOM 5893 N N   . ASP C 3 50  ? 126.644 75.233  118.991 1.00 120.12 ? 50  ASP C N   1 
ATOM 5894 C CA  . ASP C 3 50  ? 127.447 76.246  118.320 1.00 120.12 ? 50  ASP C CA  1 
ATOM 5895 C C   . ASP C 3 50  ? 128.529 76.764  119.265 1.00 120.12 ? 50  ASP C C   1 
ATOM 5896 O O   . ASP C 3 50  ? 128.352 76.785  120.486 1.00 120.12 ? 50  ASP C O   1 
ATOM 5897 C CB  . ASP C 3 50  ? 126.553 77.393  117.840 1.00 120.12 ? 50  ASP C CB  1 
ATOM 5898 C CG  . ASP C 3 50  ? 127.278 78.366  116.929 1.00 120.12 ? 50  ASP C CG  1 
ATOM 5899 O OD1 . ASP C 3 50  ? 128.199 77.931  116.207 1.00 120.12 ? 50  ASP C OD1 1 
ATOM 5900 O OD2 . ASP C 3 50  ? 126.924 79.564  116.934 1.00 120.12 ? 50  ASP C OD2 1 
ATOM 5901 N N   . ASP C 3 51  ? 129.668 77.162  118.680 1.00 120.96 ? 51  ASP C N   1 
ATOM 5902 C CA  . ASP C 3 51  ? 130.880 77.483  119.434 1.00 120.96 ? 51  ASP C CA  1 
ATOM 5903 C C   . ASP C 3 51  ? 130.744 78.698  120.354 1.00 120.96 ? 51  ASP C C   1 
ATOM 5904 O O   . ASP C 3 51  ? 131.281 78.663  121.470 1.00 120.96 ? 51  ASP C O   1 
ATOM 5905 C CB  . ASP C 3 51  ? 132.071 77.577  118.448 1.00 120.96 ? 51  ASP C CB  1 
ATOM 5906 C CG  . ASP C 3 51  ? 132.027 78.789  117.467 1.00 120.96 ? 51  ASP C CG  1 
ATOM 5907 O OD1 . ASP C 3 51  ? 131.494 79.894  117.714 1.00 120.96 ? 51  ASP C OD1 1 
ATOM 5908 O OD2 . ASP C 3 51  ? 132.576 78.604  116.361 1.00 120.96 ? 51  ASP C OD2 1 
ATOM 5909 N N   . PHE C 3 52  ? 130.039 79.746  119.904 1.00 118.15 ? 52  PHE C N   1 
ATOM 5910 C CA  . PHE C 3 52  ? 129.820 80.948  120.710 1.00 118.15 ? 52  PHE C CA  1 
ATOM 5911 C C   . PHE C 3 52  ? 129.037 80.631  121.978 1.00 118.15 ? 52  PHE C C   1 
ATOM 5912 O O   . PHE C 3 52  ? 129.399 81.087  123.071 1.00 118.15 ? 52  PHE C O   1 
ATOM 5913 C CB  . PHE C 3 52  ? 129.087 81.998  119.873 1.00 118.15 ? 52  PHE C CB  1 
ATOM 5914 C CG  . PHE C 3 52  ? 129.094 83.375  120.472 1.00 118.15 ? 52  PHE C CG  1 
ATOM 5915 C CD1 . PHE C 3 52  ? 130.217 84.185  120.369 1.00 118.15 ? 52  PHE C CD1 1 
ATOM 5916 C CD2 . PHE C 3 52  ? 127.969 83.868  121.121 1.00 118.15 ? 52  PHE C CD2 1 
ATOM 5917 C CE1 . PHE C 3 52  ? 130.224 85.461  120.915 1.00 118.15 ? 52  PHE C CE1 1 
ATOM 5918 C CE2 . PHE C 3 52  ? 127.966 85.142  121.669 1.00 118.15 ? 52  PHE C CE2 1 
ATOM 5919 C CZ  . PHE C 3 52  ? 129.096 85.939  121.565 1.00 118.15 ? 52  PHE C CZ  1 
ATOM 5920 N N   . SER C 3 53  ? 128.007 79.790  121.858 1.00 117.46 ? 53  SER C N   1 
ATOM 5921 C CA  . SER C 3 53  ? 127.262 79.254  122.989 1.00 117.46 ? 53  SER C CA  1 
ATOM 5922 C C   . SER C 3 53  ? 128.106 78.366  123.892 1.00 117.46 ? 53  SER C C   1 
ATOM 5923 O O   . SER C 3 53  ? 127.757 78.200  125.067 1.00 117.46 ? 53  SER C O   1 
ATOM 5924 C CB  . SER C 3 53  ? 126.045 78.471  122.497 1.00 117.46 ? 53  SER C CB  1 
ATOM 5925 O OG  . SER C 3 53  ? 126.438 77.354  121.723 1.00 117.46 ? 53  SER C OG  1 
ATOM 5926 N N   . ASN C 3 54  ? 129.193 77.783  123.387 1.00 120.30 ? 54  ASN C N   1 
ATOM 5927 C CA  . ASN C 3 54  ? 130.141 77.117  124.268 1.00 120.30 ? 54  ASN C CA  1 
ATOM 5928 C C   . ASN C 3 54  ? 130.932 78.101  125.114 1.00 120.30 ? 54  ASN C C   1 
ATOM 5929 O O   . ASN C 3 54  ? 131.253 77.790  126.268 1.00 120.30 ? 54  ASN C O   1 
ATOM 5930 C CB  . ASN C 3 54  ? 131.102 76.235  123.466 1.00 120.30 ? 54  ASN C CB  1 
ATOM 5931 C CG  . ASN C 3 54  ? 130.403 75.062  122.811 1.00 120.30 ? 54  ASN C CG  1 
ATOM 5932 O OD1 . ASN C 3 54  ? 130.353 74.952  121.587 1.00 120.30 ? 54  ASN C OD1 1 
ATOM 5933 N ND2 . ASN C 3 54  ? 129.849 74.178  123.631 1.00 120.30 ? 54  ASN C ND2 1 
ATOM 5934 N N   . GLN C 3 55  ? 131.223 79.289  124.563 1.00 118.89 ? 55  GLN C N   1 
ATOM 5935 C CA  . GLN C 3 55  ? 132.001 80.295  125.282 1.00 118.89 ? 55  GLN C CA  1 
ATOM 5936 C C   . GLN C 3 55  ? 131.225 80.831  126.478 1.00 118.89 ? 55  GLN C C   1 
ATOM 5937 O O   . GLN C 3 55  ? 131.769 80.933  127.588 1.00 118.89 ? 55  GLN C O   1 
ATOM 5938 C CB  . GLN C 3 55  ? 132.384 81.422  124.324 1.00 118.89 ? 55  GLN C CB  1 
ATOM 5939 C CG  . GLN C 3 55  ? 133.728 82.061  124.609 1.00 118.89 ? 55  GLN C CG  1 
ATOM 5940 C CD  . GLN C 3 55  ? 133.925 83.366  123.865 1.00 118.89 ? 55  GLN C CD  1 
ATOM 5941 O OE1 . GLN C 3 55  ? 133.717 83.447  122.655 1.00 118.89 ? 55  GLN C OE1 1 
ATOM 5942 N NE2 . GLN C 3 55  ? 134.354 84.389  124.582 1.00 118.89 ? 55  GLN C NE2 1 
ATOM 5943 N N   . LEU C 3 56  ? 129.925 81.081  126.285 1.00 117.16 ? 56  LEU C N   1 
ATOM 5944 C CA  . LEU C 3 56  ? 129.038 81.429  127.391 1.00 117.16 ? 56  LEU C CA  1 
ATOM 5945 C C   . LEU C 3 56  ? 128.855 80.256  128.350 1.00 117.16 ? 56  LEU C C   1 
ATOM 5946 O O   . LEU C 3 56  ? 128.573 80.460  129.539 1.00 117.16 ? 56  LEU C O   1 
ATOM 5947 C CB  . LEU C 3 56  ? 127.688 81.896  126.845 1.00 117.16 ? 56  LEU C CB  1 
ATOM 5948 C CG  . LEU C 3 56  ? 127.601 83.228  126.086 1.00 117.16 ? 56  LEU C CG  1 
ATOM 5949 C CD1 . LEU C 3 56  ? 126.178 83.769  126.135 1.00 117.16 ? 56  LEU C CD1 1 
ATOM 5950 C CD2 . LEU C 3 56  ? 128.585 84.265  126.609 1.00 117.16 ? 56  LEU C CD2 1 
ATOM 5951 N N   . ARG C 3 57  ? 129.073 79.020  127.865 1.00 123.19 ? 57  ARG C N   1 
ATOM 5952 C CA  . ARG C 3 57  ? 129.114 77.845  128.734 1.00 123.19 ? 57  ARG C CA  1 
ATOM 5953 C C   . ARG C 3 57  ? 130.257 77.878  129.741 1.00 123.19 ? 57  ARG C C   1 
ATOM 5954 O O   . ARG C 3 57  ? 130.201 77.147  130.735 1.00 123.19 ? 57  ARG C O   1 
ATOM 5955 C CB  . ARG C 3 57  ? 129.206 76.564  127.906 1.00 123.19 ? 57  ARG C CB  1 
ATOM 5956 C CG  . ARG C 3 57  ? 127.866 75.961  127.588 1.00 123.19 ? 57  ARG C CG  1 
ATOM 5957 C CD  . ARG C 3 57  ? 127.258 75.371  128.861 1.00 123.19 ? 57  ARG C CD  1 
ATOM 5958 N NE  . ARG C 3 57  ? 127.599 73.967  129.058 1.00 123.19 ? 57  ARG C NE  1 
ATOM 5959 C CZ  . ARG C 3 57  ? 126.980 72.954  128.468 1.00 123.19 ? 57  ARG C CZ  1 
ATOM 5960 N NH1 . ARG C 3 57  ? 125.975 73.149  127.630 1.00 123.19 ? 57  ARG C NH1 1 
ATOM 5961 N NH2 . ARG C 3 57  ? 127.378 71.712  128.728 1.00 123.19 ? 57  ARG C NH2 1 
ATOM 5962 N N   . ALA C 3 58  ? 131.292 78.690  129.519 1.00 125.06 ? 58  ALA C N   1 
ATOM 5963 C CA  . ALA C 3 58  ? 132.196 78.985  130.620 1.00 125.06 ? 58  ALA C CA  1 
ATOM 5964 C C   . ALA C 3 58  ? 131.531 79.918  131.630 1.00 125.06 ? 58  ALA C C   1 
ATOM 5965 O O   . ALA C 3 58  ? 131.419 79.585  132.817 1.00 125.06 ? 58  ALA C O   1 
ATOM 5966 C CB  . ALA C 3 58  ? 133.495 79.588  130.087 1.00 125.06 ? 58  ALA C CB  1 
ATOM 5967 N N   . GLU C 3 59  ? 131.000 81.052  131.152 1.00 120.66 ? 59  GLU C N   1 
ATOM 5968 C CA  . GLU C 3 59  ? 130.753 82.202  132.025 1.00 120.66 ? 59  GLU C CA  1 
ATOM 5969 C C   . GLU C 3 59  ? 129.518 82.008  132.895 1.00 120.66 ? 59  GLU C C   1 
ATOM 5970 O O   . GLU C 3 59  ? 129.456 82.504  134.025 1.00 120.66 ? 59  GLU C O   1 
ATOM 5971 C CB  . GLU C 3 59  ? 130.624 83.480  131.198 1.00 120.66 ? 59  GLU C CB  1 
ATOM 5972 C CG  . GLU C 3 59  ? 131.905 83.911  130.514 1.00 120.66 ? 59  GLU C CG  1 
ATOM 5973 C CD  . GLU C 3 59  ? 131.708 85.161  129.712 1.00 120.66 ? 59  GLU C CD  1 
ATOM 5974 O OE1 . GLU C 3 59  ? 130.546 85.599  129.604 1.00 120.66 ? 59  GLU C OE1 1 
ATOM 5975 O OE2 . GLU C 3 59  ? 132.708 85.695  129.205 1.00 120.66 ? 59  GLU C OE2 1 
ATOM 5976 N N   . LEU C 3 60  ? 128.516 81.293  132.383 1.00 122.52 ? 60  LEU C N   1 
ATOM 5977 C CA  . LEU C 3 60  ? 127.351 81.006  133.207 1.00 122.52 ? 60  LEU C CA  1 
ATOM 5978 C C   . LEU C 3 60  ? 127.623 79.843  134.152 1.00 122.52 ? 60  LEU C C   1 
ATOM 5979 O O   . LEU C 3 60  ? 126.901 79.677  135.141 1.00 122.52 ? 60  LEU C O   1 
ATOM 5980 C CB  . LEU C 3 60  ? 126.137 80.744  132.304 1.00 122.52 ? 60  LEU C CB  1 
ATOM 5981 C CG  . LEU C 3 60  ? 124.703 80.730  132.855 1.00 122.52 ? 60  LEU C CG  1 
ATOM 5982 C CD1 . LEU C 3 60  ? 123.759 81.406  131.876 1.00 122.52 ? 60  LEU C CD1 1 
ATOM 5983 C CD2 . LEU C 3 60  ? 124.224 79.313  133.122 1.00 122.52 ? 60  LEU C CD2 1 
ATOM 5984 N N   . GLU C 3 61  ? 128.687 79.070  133.902 1.00 133.96 ? 61  GLU C N   1 
ATOM 5985 C CA  . GLU C 3 61  ? 129.050 77.938  134.746 1.00 133.96 ? 61  GLU C CA  1 
ATOM 5986 C C   . GLU C 3 61  ? 130.336 78.204  135.521 1.00 133.96 ? 61  GLU C C   1 
ATOM 5987 O O   . GLU C 3 61  ? 130.899 77.297  136.138 1.00 133.96 ? 61  GLU C O   1 
ATOM 5988 C CB  . GLU C 3 61  ? 129.164 76.661  133.913 1.00 133.96 ? 61  GLU C CB  1 
ATOM 5989 C CG  . GLU C 3 61  ? 127.831 75.952  133.678 1.00 133.96 ? 61  GLU C CG  1 
ATOM 5990 C CD  . GLU C 3 61  ? 127.010 76.538  132.535 1.00 133.96 ? 61  GLU C CD  1 
ATOM 5991 O OE1 . GLU C 3 61  ? 127.477 77.480  131.859 1.00 133.96 ? 61  GLU C OE1 1 
ATOM 5992 O OE2 . GLU C 3 61  ? 125.882 76.048  132.316 1.00 133.96 ? 61  GLU C OE2 1 
ATOM 5993 N N   . LYS C 3 62  ? 130.809 79.450  135.497 1.00 128.70 ? 62  LYS C N   1 
ATOM 5994 C CA  . LYS C 3 62  ? 131.907 79.879  136.349 1.00 128.70 ? 62  LYS C CA  1 
ATOM 5995 C C   . LYS C 3 62  ? 131.404 80.585  137.602 1.00 128.70 ? 62  LYS C C   1 
ATOM 5996 O O   . LYS C 3 62  ? 132.093 80.576  138.627 1.00 128.70 ? 62  LYS C O   1 
ATOM 5997 C CB  . LYS C 3 62  ? 132.853 80.808  135.556 1.00 128.70 ? 62  LYS C CB  1 
ATOM 5998 C CG  . LYS C 3 62  ? 134.192 81.336  136.188 1.00 128.70 ? 62  LYS C CG  1 
ATOM 5999 C CD  . LYS C 3 62  ? 135.038 80.482  137.192 1.00 128.70 ? 62  LYS C CD  1 
ATOM 6000 C CE  . LYS C 3 62  ? 135.411 79.050  136.743 1.00 128.70 ? 62  LYS C CE  1 
ATOM 6001 N NZ  . LYS C 3 62  ? 136.155 78.296  137.791 1.00 128.70 ? 62  LYS C NZ  1 
ATOM 6002 N N   . HIS C 3 63  ? 130.196 81.142  137.563 1.00 124.50 ? 63  HIS C N   1 
ATOM 6003 C CA  . HIS C 3 63  ? 129.598 81.814  138.708 1.00 124.50 ? 63  HIS C CA  1 
ATOM 6004 C C   . HIS C 3 63  ? 128.848 80.855  139.627 1.00 124.50 ? 63  HIS C C   1 
ATOM 6005 O O   . HIS C 3 63  ? 128.214 81.305  140.587 1.00 124.50 ? 63  HIS C O   1 
ATOM 6006 C CB  . HIS C 3 63  ? 128.663 82.928  138.232 1.00 124.50 ? 63  HIS C CB  1 
ATOM 6007 C CG  . HIS C 3 63  ? 129.375 84.083  137.598 1.00 124.50 ? 63  HIS C CG  1 
ATOM 6008 N ND1 . HIS C 3 63  ? 129.730 84.095  136.267 1.00 124.50 ? 63  HIS C ND1 1 
ATOM 6009 C CD2 . HIS C 3 63  ? 129.798 85.263  138.111 1.00 124.50 ? 63  HIS C CD2 1 
ATOM 6010 C CE1 . HIS C 3 63  ? 130.343 85.232  135.987 1.00 124.50 ? 63  HIS C CE1 1 
ATOM 6011 N NE2 . HIS C 3 63  ? 130.396 85.958  137.089 1.00 124.50 ? 63  HIS C NE2 1 
ATOM 6012 N N   . GLY C 3 64  ? 128.903 79.555  139.355 1.00 127.95 ? 64  GLY C N   1 
ATOM 6013 C CA  . GLY C 3 64  ? 128.288 78.576  140.237 1.00 127.95 ? 64  GLY C CA  1 
ATOM 6014 C C   . GLY C 3 64  ? 126.797 78.408  140.041 1.00 127.95 ? 64  GLY C C   1 
ATOM 6015 O O   . GLY C 3 64  ? 126.117 77.860  140.917 1.00 127.95 ? 64  GLY C O   1 
ATOM 6016 N N   . TYR C 3 65  ? 126.270 78.868  138.909 1.00 125.49 ? 65  TYR C N   1 
ATOM 6017 C CA  . TYR C 3 65  ? 124.849 78.724  138.598 1.00 125.49 ? 65  TYR C CA  1 
ATOM 6018 C C   . TYR C 3 65  ? 124.748 77.780  137.410 1.00 125.49 ? 65  TYR C C   1 
ATOM 6019 O O   . TYR C 3 65  ? 124.638 78.232  136.267 1.00 125.49 ? 65  TYR C O   1 
ATOM 6020 C CB  . TYR C 3 65  ? 124.207 80.078  138.280 1.00 125.49 ? 65  TYR C CB  1 
ATOM 6021 C CG  . TYR C 3 65  ? 123.740 80.880  139.485 1.00 125.49 ? 65  TYR C CG  1 
ATOM 6022 C CD1 . TYR C 3 65  ? 124.215 80.602  140.767 1.00 125.49 ? 65  TYR C CD1 1 
ATOM 6023 C CD2 . TYR C 3 65  ? 122.839 81.931  139.333 1.00 125.49 ? 65  TYR C CD2 1 
ATOM 6024 C CE1 . TYR C 3 65  ? 123.797 81.339  141.864 1.00 125.49 ? 65  TYR C CE1 1 
ATOM 6025 C CE2 . TYR C 3 65  ? 122.414 82.676  140.426 1.00 125.49 ? 65  TYR C CE2 1 
ATOM 6026 C CZ  . TYR C 3 65  ? 122.898 82.373  141.686 1.00 125.49 ? 65  TYR C CZ  1 
ATOM 6027 O OH  . TYR C 3 65  ? 122.483 83.106  142.774 1.00 125.49 ? 65  TYR C OH  1 
ATOM 6028 N N   . LYS C 3 66  ? 124.768 76.474  137.671 1.00 126.25 ? 66  LYS C N   1 
ATOM 6029 C CA  . LYS C 3 66  ? 124.915 75.501  136.600 1.00 126.25 ? 66  LYS C CA  1 
ATOM 6030 C C   . LYS C 3 66  ? 123.673 74.627  136.512 1.00 126.25 ? 66  LYS C C   1 
ATOM 6031 O O   . LYS C 3 66  ? 123.104 74.223  137.530 1.00 126.25 ? 66  LYS C O   1 
ATOM 6032 C CB  . LYS C 3 66  ? 126.159 74.627  136.805 1.00 126.25 ? 66  LYS C CB  1 
ATOM 6033 N N   . MET C 3 67  ? 123.267 74.338  135.279 1.00 118.42 ? 67  MET C N   1 
ATOM 6034 C CA  . MET C 3 67  ? 122.126 73.472  135.016 1.00 118.42 ? 67  MET C CA  1 
ATOM 6035 C C   . MET C 3 67  ? 122.338 72.798  133.667 1.00 118.42 ? 67  MET C C   1 
ATOM 6036 O O   . MET C 3 67  ? 123.137 73.250  132.843 1.00 118.42 ? 67  MET C O   1 
ATOM 6037 C CB  . MET C 3 67  ? 120.809 74.253  135.042 1.00 118.42 ? 67  MET C CB  1 
ATOM 6038 N N   . GLU C 3 68  ? 121.611 71.706  133.455 1.00 119.48 ? 68  GLU C N   1 
ATOM 6039 C CA  . GLU C 3 68  ? 121.731 70.934  132.222 1.00 119.48 ? 68  GLU C CA  1 
ATOM 6040 C C   . GLU C 3 68  ? 121.057 71.642  131.051 1.00 119.48 ? 68  GLU C C   1 
ATOM 6041 O O   . GLU C 3 68  ? 121.696 71.939  130.041 1.00 119.48 ? 68  GLU C O   1 
ATOM 6042 C CB  . GLU C 3 68  ? 121.132 69.537  132.406 1.00 119.48 ? 68  GLU C CB  1 
# 
