data_8R7F
# 
_entry.id   8R7F 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R7F         pdb_00008r7f 10.2210/pdb8r7f/pdb 
WWPDB D_1292134854 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-12-04 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R7F 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-24 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ajt208@cam.ac.uk 
_pdbx_contact_author.name_first         Jussi 
_pdbx_contact_author.name_last          Taipale 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4204-0951 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Morgunova, E.' 1 0000-0002-7754-9021 
'Popov, A.'     2 0000-0002-3058-8912 
'Yin, Y.'       3 0000-0002-5454-608X 
'Taipale, J.'   4 0000-0003-4204-0951 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of transcription factor BARHL2 homodimer bound to specific DNA' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Morgunova, E.' 1 0000-0002-7754-9021 
primary 'Popov, A.'     2 0000-0002-3058-8912 
primary 'Yin, Y.'       3 0000-0002-5454-608X 
primary 'Taipale, J.'   4 0000-0003-4204-0951 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer syn 
;DNA (5'-D(*CP*TP*AP*AP*AP*CP*GP*GP*GP*CP*AP*AP*TP*TP*AP*G)-3')
;
4931.230 1 ? ? ? ? 
2 polymer syn 
;DNA (5'-D(*CP*TP*AP*AP*TP*TP*GP*CP*CP*CP*GP*TP*TP*TP*AP*G)-3')
;
4864.165 1 ? ? ? ? 
3 polymer man 'BarH-like 2 homeobox protein'                                   7637.618 1 ? ? ? ? 
4 polymer man 'BarH-like 2 homeobox protein'                                   7668.716 1 ? ? ? ? 
5 water   nat water                                                            18.015   9 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 polydeoxyribonucleotide no no '(DC)(DT)(DA)(DA)(DA)(DC)(DG)(DG)(DG)(DC)(DA)(DA)(DT)(DT)(DA)(DG)' CTAAACGGGCAATTAG B ? 
2 polydeoxyribonucleotide no no '(DC)(DT)(DA)(DA)(DT)(DT)(DG)(DC)(DC)(DC)(DG)(DT)(DT)(DT)(DA)(DG)' CTAATTGCCCGTTTAG D ? 
3 'polypeptide(L)'        no no APRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVG   
APRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVG A ? 
4 'polypeptide(L)'        no no KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTA    
KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTA  E ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1  DC  n 
1 2  DT  n 
1 3  DA  n 
1 4  DA  n 
1 5  DA  n 
1 6  DC  n 
1 7  DG  n 
1 8  DG  n 
1 9  DG  n 
1 10 DC  n 
1 11 DA  n 
1 12 DA  n 
1 13 DT  n 
1 14 DT  n 
1 15 DA  n 
1 16 DG  n 
2 1  DC  n 
2 2  DT  n 
2 3  DA  n 
2 4  DA  n 
2 5  DT  n 
2 6  DT  n 
2 7  DG  n 
2 8  DC  n 
2 9  DC  n 
2 10 DC  n 
2 11 DG  n 
2 12 DT  n 
2 13 DT  n 
2 14 DT  n 
2 15 DA  n 
2 16 DG  n 
3 1  ALA n 
3 2  PRO n 
3 3  ARG n 
3 4  LYS n 
3 5  ALA n 
3 6  ARG n 
3 7  THR n 
3 8  ALA n 
3 9  PHE n 
3 10 SER n 
3 11 ASP n 
3 12 HIS n 
3 13 GLN n 
3 14 LEU n 
3 15 ASN n 
3 16 GLN n 
3 17 LEU n 
3 18 GLU n 
3 19 ARG n 
3 20 SER n 
3 21 PHE n 
3 22 GLU n 
3 23 ARG n 
3 24 GLN n 
3 25 LYS n 
3 26 TYR n 
3 27 LEU n 
3 28 SER n 
3 29 VAL n 
3 30 GLN n 
3 31 ASP n 
3 32 ARG n 
3 33 MET n 
3 34 ASP n 
3 35 LEU n 
3 36 ALA n 
3 37 ALA n 
3 38 ALA n 
3 39 LEU n 
3 40 ASN n 
3 41 LEU n 
3 42 THR n 
3 43 ASP n 
3 44 THR n 
3 45 GLN n 
3 46 VAL n 
3 47 LYS n 
3 48 THR n 
3 49 TRP n 
3 50 TYR n 
3 51 GLN n 
3 52 ASN n 
3 53 ARG n 
3 54 ARG n 
3 55 THR n 
3 56 LYS n 
3 57 TRP n 
3 58 LYS n 
3 59 ARG n 
3 60 GLN n 
3 61 THR n 
3 62 ALA n 
3 63 VAL n 
3 64 GLY n 
4 1  LYS n 
4 2  LYS n 
4 3  PRO n 
4 4  ARG n 
4 5  LYS n 
4 6  ALA n 
4 7  ARG n 
4 8  THR n 
4 9  ALA n 
4 10 PHE n 
4 11 SER n 
4 12 ASP n 
4 13 HIS n 
4 14 GLN n 
4 15 LEU n 
4 16 ASN n 
4 17 GLN n 
4 18 LEU n 
4 19 GLU n 
4 20 ARG n 
4 21 SER n 
4 22 PHE n 
4 23 GLU n 
4 24 ARG n 
4 25 GLN n 
4 26 LYS n 
4 27 TYR n 
4 28 LEU n 
4 29 SER n 
4 30 VAL n 
4 31 GLN n 
4 32 ASP n 
4 33 ARG n 
4 34 MET n 
4 35 ASP n 
4 36 LEU n 
4 37 ALA n 
4 38 ALA n 
4 39 ALA n 
4 40 LEU n 
4 41 ASN n 
4 42 LEU n 
4 43 THR n 
4 44 ASP n 
4 45 THR n 
4 46 GLN n 
4 47 VAL n 
4 48 LYS n 
4 49 THR n 
4 50 TRP n 
4 51 TYR n 
4 52 GLN n 
4 53 ASN n 
4 54 ARG n 
4 55 ARG n 
4 56 THR n 
4 57 LYS n 
4 58 TRP n 
4 59 LYS n 
4 60 ARG n 
4 61 GLN n 
4 62 THR n 
4 63 ALA n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
3 1 sample 'Biological sequence' 1 64 human ? BARHL2 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 562 ? ? ? 
? ? ? ? ? ? ? ? ? ? ? plasmid ? ? ? pETG20A-SBP ? ? 
4 1 sample 'Biological sequence' 1 63 human ? BARHL2 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli' 562 ? ? ? 
? ? ? ? ? ? ? ? ? ? ? plasmid ? ? ? pETG20A-SBP ? ? 
# 
loop_
_pdbx_entity_src_syn.entity_id 
_pdbx_entity_src_syn.pdbx_src_id 
_pdbx_entity_src_syn.pdbx_alt_source_flag 
_pdbx_entity_src_syn.pdbx_beg_seq_num 
_pdbx_entity_src_syn.pdbx_end_seq_num 
_pdbx_entity_src_syn.organism_scientific 
_pdbx_entity_src_syn.organism_common_name 
_pdbx_entity_src_syn.ncbi_taxonomy_id 
_pdbx_entity_src_syn.details 
1 1 sample 1 16 'Homo sapiens' ? 9606 ? 
2 1 sample 1 16 'Homo sapiens' ? 9606 ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'      133.103 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P' 322.208 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER                                ? 'H2 O'            18.015  
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1  DC  1  1   1   DC  DC  B . n 
A 1 2  DT  2  2   2   DT  DT  B . n 
A 1 3  DA  3  3   3   DA  DA  B . n 
A 1 4  DA  4  4   4   DA  DA  B . n 
A 1 5  DA  5  5   5   DA  DA  B . n 
A 1 6  DC  6  6   6   DC  DC  B . n 
A 1 7  DG  7  7   7   DG  DG  B . n 
A 1 8  DG  8  8   8   DG  DG  B . n 
A 1 9  DG  9  9   9   DG  DG  B . n 
A 1 10 DC  10 10  10  DC  DC  B . n 
A 1 11 DA  11 11  11  DA  DA  B . n 
A 1 12 DA  12 12  12  DA  DA  B . n 
A 1 13 DT  13 13  13  DT  DT  B . n 
A 1 14 DT  14 14  14  DT  DT  B . n 
A 1 15 DA  15 15  15  DA  DA  B . n 
A 1 16 DG  16 16  16  DG  DG  B . n 
B 2 1  DC  1  1   1   DC  DC  D . n 
B 2 2  DT  2  2   2   DT  DT  D . n 
B 2 3  DA  3  3   3   DA  DA  D . n 
B 2 4  DA  4  4   4   DA  DA  D . n 
B 2 5  DT  5  5   5   DT  DT  D . n 
B 2 6  DT  6  6   6   DT  DT  D . n 
B 2 7  DG  7  7   7   DG  DG  D . n 
B 2 8  DC  8  8   8   DC  DC  D . n 
B 2 9  DC  9  9   9   DC  DC  D . n 
B 2 10 DC  10 10  10  DC  DC  D . n 
B 2 11 DG  11 11  11  DG  DG  D . n 
B 2 12 DT  12 12  12  DT  DT  D . n 
B 2 13 DT  13 13  13  DT  DT  D . n 
B 2 14 DT  14 14  14  DT  DT  D . n 
B 2 15 DA  15 15  15  DA  DA  D . n 
B 2 16 DG  16 16  16  DG  DG  D . n 
C 3 1  ALA 1  231 231 ALA ALA A . n 
C 3 2  PRO 2  232 232 PRO PRO A . n 
C 3 3  ARG 3  233 233 ARG ARG A . n 
C 3 4  LYS 4  234 234 LYS LYS A . n 
C 3 5  ALA 5  235 235 ALA ALA A . n 
C 3 6  ARG 6  236 236 ARG ARG A . n 
C 3 7  THR 7  237 237 THR THR A . n 
C 3 8  ALA 8  238 238 ALA ALA A . n 
C 3 9  PHE 9  239 239 PHE PHE A . n 
C 3 10 SER 10 240 240 SER SER A . n 
C 3 11 ASP 11 241 241 ASP ASP A . n 
C 3 12 HIS 12 242 242 HIS HIS A . n 
C 3 13 GLN 13 243 243 GLN GLN A . n 
C 3 14 LEU 14 244 244 LEU LEU A . n 
C 3 15 ASN 15 245 245 ASN ASN A . n 
C 3 16 GLN 16 246 246 GLN GLN A . n 
C 3 17 LEU 17 247 247 LEU LEU A . n 
C 3 18 GLU 18 248 248 GLU GLU A . n 
C 3 19 ARG 19 249 249 ARG ARG A . n 
C 3 20 SER 20 250 250 SER SER A . n 
C 3 21 PHE 21 251 251 PHE PHE A . n 
C 3 22 GLU 22 252 252 GLU GLU A . n 
C 3 23 ARG 23 253 253 ARG ARG A . n 
C 3 24 GLN 24 254 254 GLN GLN A . n 
C 3 25 LYS 25 255 255 LYS LYS A . n 
C 3 26 TYR 26 256 256 TYR TYR A . n 
C 3 27 LEU 27 257 257 LEU LEU A . n 
C 3 28 SER 28 258 258 SER SER A . n 
C 3 29 VAL 29 259 259 VAL VAL A . n 
C 3 30 GLN 30 260 260 GLN GLN A . n 
C 3 31 ASP 31 261 261 ASP ASP A . n 
C 3 32 ARG 32 262 262 ARG ARG A . n 
C 3 33 MET 33 263 263 MET MET A . n 
C 3 34 ASP 34 264 264 ASP ASP A . n 
C 3 35 LEU 35 265 265 LEU LEU A . n 
C 3 36 ALA 36 266 266 ALA ALA A . n 
C 3 37 ALA 37 267 267 ALA ALA A . n 
C 3 38 ALA 38 268 268 ALA ALA A . n 
C 3 39 LEU 39 269 269 LEU LEU A . n 
C 3 40 ASN 40 270 270 ASN ASN A . n 
C 3 41 LEU 41 271 271 LEU LEU A . n 
C 3 42 THR 42 272 272 THR THR A . n 
C 3 43 ASP 43 273 273 ASP ASP A . n 
C 3 44 THR 44 274 274 THR THR A . n 
C 3 45 GLN 45 275 275 GLN GLN A . n 
C 3 46 VAL 46 276 276 VAL VAL A . n 
C 3 47 LYS 47 277 277 LYS LYS A . n 
C 3 48 THR 48 278 278 THR THR A . n 
C 3 49 TRP 49 279 279 TRP TRP A . n 
C 3 50 TYR 50 280 280 TYR TYR A . n 
C 3 51 GLN 51 281 281 GLN GLN A . n 
C 3 52 ASN 52 282 282 ASN ASN A . n 
C 3 53 ARG 53 283 283 ARG ARG A . n 
C 3 54 ARG 54 284 284 ARG ARG A . n 
C 3 55 THR 55 285 285 THR THR A . n 
C 3 56 LYS 56 286 286 LYS LYS A . n 
C 3 57 TRP 57 287 287 TRP TRP A . n 
C 3 58 LYS 58 288 288 LYS LYS A . n 
C 3 59 ARG 59 289 289 ARG ARG A . n 
C 3 60 GLN 60 290 290 GLN GLN A . n 
C 3 61 THR 61 291 291 THR THR A . n 
C 3 62 ALA 62 292 292 ALA ALA A . n 
C 3 63 VAL 63 293 293 VAL VAL A . n 
C 3 64 GLY 64 294 294 GLY GLY A . n 
D 4 1  LYS 1  230 230 LYS LYS E . n 
D 4 2  LYS 2  231 231 LYS LYS E . n 
D 4 3  PRO 3  232 232 PRO PRO E . n 
D 4 4  ARG 4  233 233 ARG ARG E . n 
D 4 5  LYS 5  234 234 LYS LYS E . n 
D 4 6  ALA 6  235 235 ALA ALA E . n 
D 4 7  ARG 7  236 236 ARG ARG E . n 
D 4 8  THR 8  237 237 THR THR E . n 
D 4 9  ALA 9  238 238 ALA ALA E . n 
D 4 10 PHE 10 239 239 PHE PHE E . n 
D 4 11 SER 11 240 240 SER SER E . n 
D 4 12 ASP 12 241 241 ASP ASP E . n 
D 4 13 HIS 13 242 242 HIS HIS E . n 
D 4 14 GLN 14 243 243 GLN GLN E . n 
D 4 15 LEU 15 244 244 LEU LEU E . n 
D 4 16 ASN 16 245 245 ASN ASN E . n 
D 4 17 GLN 17 246 246 GLN GLN E . n 
D 4 18 LEU 18 247 247 LEU LEU E . n 
D 4 19 GLU 19 248 248 GLU GLU E . n 
D 4 20 ARG 20 249 249 ARG ARG E . n 
D 4 21 SER 21 250 250 SER SER E . n 
D 4 22 PHE 22 251 251 PHE PHE E . n 
D 4 23 GLU 23 252 252 GLU GLU E . n 
D 4 24 ARG 24 253 253 ARG ARG E . n 
D 4 25 GLN 25 254 254 GLN GLN E . n 
D 4 26 LYS 26 255 255 LYS LYS E . n 
D 4 27 TYR 27 256 256 TYR TYR E . n 
D 4 28 LEU 28 257 257 LEU LEU E . n 
D 4 29 SER 29 258 258 SER SER E . n 
D 4 30 VAL 30 259 259 VAL VAL E . n 
D 4 31 GLN 31 260 260 GLN GLN E . n 
D 4 32 ASP 32 261 261 ASP ASP E . n 
D 4 33 ARG 33 262 262 ARG ARG E . n 
D 4 34 MET 34 263 263 MET MET E . n 
D 4 35 ASP 35 264 264 ASP ASP E . n 
D 4 36 LEU 36 265 265 LEU LEU E . n 
D 4 37 ALA 37 266 266 ALA ALA E . n 
D 4 38 ALA 38 267 267 ALA ALA E . n 
D 4 39 ALA 39 268 268 ALA ALA E . n 
D 4 40 LEU 40 269 269 LEU LEU E . n 
D 4 41 ASN 41 270 270 ASN ASN E . n 
D 4 42 LEU 42 271 271 LEU LEU E . n 
D 4 43 THR 43 272 272 THR THR E . n 
D 4 44 ASP 44 273 273 ASP ASP E . n 
D 4 45 THR 45 274 274 THR THR E . n 
D 4 46 GLN 46 275 275 GLN GLN E . n 
D 4 47 VAL 47 276 276 VAL VAL E . n 
D 4 48 LYS 48 277 277 LYS LYS E . n 
D 4 49 THR 49 278 278 THR THR E . n 
D 4 50 TRP 50 279 279 TRP TRP E . n 
D 4 51 TYR 51 280 280 TYR TYR E . n 
D 4 52 GLN 52 281 281 GLN GLN E . n 
D 4 53 ASN 53 282 282 ASN ASN E . n 
D 4 54 ARG 54 283 283 ARG ARG E . n 
D 4 55 ARG 55 284 284 ARG ARG E . n 
D 4 56 THR 56 285 285 THR THR E . n 
D 4 57 LYS 57 286 286 LYS LYS E . n 
D 4 58 TRP 58 287 287 TRP TRP E . n 
D 4 59 LYS 59 288 288 LYS LYS E . n 
D 4 60 ARG 60 289 289 ARG ARG E . n 
D 4 61 GLN 61 290 290 GLN GLN E . n 
D 4 62 THR 62 291 291 THR THR E . n 
D 4 63 ALA 63 292 292 ALA ALA E . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 5 HOH 1 101 16 HOH HOH B . 
E 5 HOH 2 102 17 HOH HOH B . 
F 5 HOH 1 101 14 HOH HOH D . 
F 5 HOH 2 102 15 HOH HOH D . 
G 5 HOH 1 301 3  HOH HOH A . 
G 5 HOH 2 302 6  HOH HOH A . 
G 5 HOH 3 303 5  HOH HOH A . 
H 5 HOH 1 301 10 HOH HOH E . 
H 5 HOH 2 302 13 HOH HOH E . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0419 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   111.72 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R7F 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     45.335 
_cell.length_a_esd                 ? 
_cell.length_b                     63.169 
_cell.length_b_esd                 ? 
_cell.length_c                     51.323 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        2 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R7F 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R7F 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.62 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          58 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;Sodium Cacodilate buffer (pH 6.5), 
PEG (4000) 
5% butanol
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M-F' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-07-16 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.619920 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE ID23-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.619920 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ID23-1 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8R7F 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.98 
_reflns.d_resolution_low                               47.68 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     18391 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.2 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                5.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          4.6 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               0.66 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.092 
_reflns.pdbx_Rpim_I_all                                0.039 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       100419 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.083 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.98 
_reflns_shell.d_res_low                                     2.03 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           5704 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1164 
_reflns_shell.percent_possible_obs                          88.6 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               4.9 
_reflns_shell.pdbx_chi_squared                              0.58 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     0.5 
_reflns_shell.pdbx_Rrim_I_all                               3.821 
_reflns_shell.pdbx_Rpim_I_all                               1.656 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.414 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  3.426 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            1.86 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            1.66 
_refine.aniso_B[2][2]                            2.56 
_refine.aniso_B[2][3]                            0.00 
_refine.aniso_B[3][3]                            -4.35 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               73.212 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.959 
_refine.correlation_coeff_Fo_to_Fc_free          0.956 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8R7F 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.98 
_refine.ls_d_res_low                             47.68 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     17365 
_refine.ls_number_reflns_R_free                  905 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    97.49 
_refine.ls_percent_reflns_R_free                 5.0 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.23476 
_refine.ls_R_factor_R_free                       0.27262 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.23269 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.193 
_refine.pdbx_overall_ESU_R_Free                  0.175 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             23.172 
_refine.overall_SU_ML                            0.250 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.98 
_refine_hist.d_res_low                        47.68 
_refine_hist.number_atoms_solvent             9 
_refine_hist.number_atoms_total               1735 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1076 
_refine_hist.pdbx_number_atoms_nucleic_acid   650 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  0.011  1822 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  1426 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 2.174  1.836  2588 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.571  1.770  3281 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.178  5.000  125  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 7.576  5.000  16   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 17.770 10.000 213  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.084  0.200  281  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.010  0.020  1739 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  417  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 5.439  5.387  506  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.436  5.389  506  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 7.667  9.607  629  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 7.665  9.607  630  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 5.157  5.494  1316 ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.155  5.495  1317 ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 7.337  9.912  1960 ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 9.690  57.84  2328 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 9.684  57.84  2328 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       1.984 
_refine_ls_shell.d_res_low                        2.035 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             60 
_refine_ls_shell.number_reflns_R_work             1116 
_refine_ls_shell.percent_reflns_obs               84.54 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.498 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.487 
# 
_struct.entry_id                     8R7F 
_struct.title                        'Transcription factor BARHL2 homodimer with spacing two bp' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R7F 
_struct_keywords.text            'transcription factor, homeobox protein, homodimer, complex with specific DNA, TRANSCRIPTION' 
_struct_keywords.pdbx_keywords   TRANSCRIPTION 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 5 ? 
G N N 5 ? 
H N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8R7F        8R7F   ? 1 ?                                                               1   
2 PDB 8R7F        8R7F   ? 2 ?                                                               1   
3 UNP BARH2_HUMAN Q9NY43 ? 3 PRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVG 232 
4 UNP BARH2_HUMAN Q9NY43 ? 4 KKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTA 230 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8R7F B 1 ? 16 ? 8R7F   1   ? 16  ? 1   16  
2 2 8R7F D 1 ? 16 ? 8R7F   1   ? 16  ? 1   16  
3 3 8R7F A 2 ? 64 ? Q9NY43 232 ? 294 ? 232 294 
4 4 8R7F E 1 ? 63 ? Q9NY43 230 ? 292 ? 230 292 
# 
_struct_ref_seq_dif.align_id                     3 
_struct_ref_seq_dif.pdbx_pdb_id_code             8R7F 
_struct_ref_seq_dif.mon_id                       ALA 
_struct_ref_seq_dif.pdbx_pdb_strand_id           A 
_struct_ref_seq_dif.seq_num                      1 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   Q9NY43 
_struct_ref_seq_dif.db_mon_id                    ? 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          ? 
_struct_ref_seq_dif.details                      'expression tag' 
_struct_ref_seq_dif.pdbx_auth_seq_num            231 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 5560  ? 
1 MORE         -27   ? 
1 'SSA (A^2)'  12210 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 SER C 10 ? GLN C 24 ? SER A 240 GLN A 254 1 ? 15 
HELX_P HELX_P2 AA2 SER C 28 ? LEU C 39 ? SER A 258 LEU A 269 1 ? 12 
HELX_P HELX_P3 AA3 THR C 42 ? VAL C 63 ? THR A 272 VAL A 293 1 ? 22 
HELX_P HELX_P4 AA4 SER D 11 ? GLN D 25 ? SER E 240 GLN E 254 1 ? 15 
HELX_P HELX_P5 AA5 SER D 29 ? ASN D 41 ? SER E 258 ASN E 270 1 ? 13 
HELX_P HELX_P6 AA6 THR D 43 ? ALA D 63 ? THR E 272 ALA E 292 1 ? 21 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
hydrog1  hydrog ? ? A DC 1  N3 ? ? ? 1_555 B DG 16 N1 ? ? B DC 1  D DG 16 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog2  hydrog ? ? A DC 1  N4 ? ? ? 1_555 B DG 16 O6 ? ? B DC 1  D DG 16 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog3  hydrog ? ? A DC 1  O2 ? ? ? 1_555 B DG 16 N2 ? ? B DC 1  D DG 16 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog4  hydrog ? ? A DT 2  N3 ? ? ? 1_555 B DA 15 N1 ? ? B DT 2  D DA 15 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog5  hydrog ? ? A DT 2  O4 ? ? ? 1_555 B DA 15 N6 ? ? B DT 2  D DA 15 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog6  hydrog ? ? A DA 3  N1 ? ? ? 1_555 B DT 14 N3 ? ? B DA 3  D DT 14 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog7  hydrog ? ? A DA 3  N6 ? ? ? 1_555 B DT 14 O4 ? ? B DA 3  D DT 14 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog8  hydrog ? ? A DA 4  N1 ? ? ? 1_555 B DT 13 N3 ? ? B DA 4  D DT 13 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog9  hydrog ? ? A DA 4  N6 ? ? ? 1_555 B DT 13 O4 ? ? B DA 4  D DT 13 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog10 hydrog ? ? A DA 5  N1 ? ? ? 1_555 B DT 12 N3 ? ? B DA 5  D DT 12 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog11 hydrog ? ? A DA 5  N6 ? ? ? 1_555 B DT 12 O4 ? ? B DA 5  D DT 12 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog12 hydrog ? ? A DC 6  N3 ? ? ? 1_555 B DG 11 N1 ? ? B DC 6  D DG 11 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog13 hydrog ? ? A DC 6  N4 ? ? ? 1_555 B DG 11 O6 ? ? B DC 6  D DG 11 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog14 hydrog ? ? A DC 6  O2 ? ? ? 1_555 B DG 11 N2 ? ? B DC 6  D DG 11 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog15 hydrog ? ? A DG 7  N1 ? ? ? 1_555 B DC 10 N3 ? ? B DG 7  D DC 10 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog16 hydrog ? ? A DG 7  N2 ? ? ? 1_555 B DC 10 O2 ? ? B DG 7  D DC 10 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog17 hydrog ? ? A DG 7  O6 ? ? ? 1_555 B DC 10 N4 ? ? B DG 7  D DC 10 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog18 hydrog ? ? A DG 8  N1 ? ? ? 1_555 B DC 9  N3 ? ? B DG 8  D DC 9  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog19 hydrog ? ? A DG 8  N2 ? ? ? 1_555 B DC 9  O2 ? ? B DG 8  D DC 9  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog20 hydrog ? ? A DG 8  O6 ? ? ? 1_555 B DC 9  N4 ? ? B DG 8  D DC 9  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog21 hydrog ? ? A DG 9  N1 ? ? ? 1_555 B DC 8  N3 ? ? B DG 9  D DC 8  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog22 hydrog ? ? A DG 9  N2 ? ? ? 1_555 B DC 8  O2 ? ? B DG 9  D DC 8  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog23 hydrog ? ? A DG 9  O6 ? ? ? 1_555 B DC 8  N4 ? ? B DG 9  D DC 8  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog24 hydrog ? ? A DC 10 N3 ? ? ? 1_555 B DG 7  N1 ? ? B DC 10 D DG 7  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog25 hydrog ? ? A DC 10 N4 ? ? ? 1_555 B DG 7  O6 ? ? B DC 10 D DG 7  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog26 hydrog ? ? A DC 10 O2 ? ? ? 1_555 B DG 7  N2 ? ? B DC 10 D DG 7  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog27 hydrog ? ? A DA 11 N1 ? ? ? 1_555 B DT 6  N3 ? ? B DA 11 D DT 6  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog28 hydrog ? ? A DA 11 N6 ? ? ? 1_555 B DT 6  O4 ? ? B DA 11 D DT 6  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog29 hydrog ? ? A DA 12 N1 ? ? ? 1_555 B DT 5  N3 ? ? B DA 12 D DT 5  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog30 hydrog ? ? A DA 12 N6 ? ? ? 1_555 B DT 5  O4 ? ? B DA 12 D DT 5  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog31 hydrog ? ? A DT 13 N3 ? ? ? 1_555 B DA 4  N1 ? ? B DT 13 D DA 4  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog32 hydrog ? ? A DT 13 O4 ? ? ? 1_555 B DA 4  N6 ? ? B DT 13 D DA 4  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog33 hydrog ? ? A DT 14 N3 ? ? ? 1_555 B DA 3  N1 ? ? B DT 14 D DA 3  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog34 hydrog ? ? A DT 14 O4 ? ? ? 1_555 B DA 3  N6 ? ? B DT 14 D DA 3  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog35 hydrog ? ? A DA 15 N1 ? ? ? 1_555 B DT 2  N3 ? ? B DA 15 D DT 2  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog36 hydrog ? ? A DA 15 N6 ? ? ? 1_555 B DT 2  O4 ? ? B DA 15 D DT 2  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog37 hydrog ? ? A DG 16 N1 ? ? ? 1_555 B DC 1  N3 ? ? B DG 16 D DC 1  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog38 hydrog ? ? A DG 16 N2 ? ? ? 1_555 B DC 1  O2 ? ? B DG 16 D DC 1  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog39 hydrog ? ? A DG 16 O6 ? ? ? 1_555 B DC 1  N4 ? ? B DG 16 D DC 1  1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
# 
_struct_conn_type.id          hydrog 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_entry_details.entry_id                   8R7F 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OP1 
_pdbx_validate_close_contact.auth_asym_id_1   D 
_pdbx_validate_close_contact.auth_comp_id_1   DC 
_pdbx_validate_close_contact.auth_seq_id_1    10 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OH 
_pdbx_validate_close_contact.auth_asym_id_2   A 
_pdbx_validate_close_contact.auth_comp_id_2   TYR 
_pdbx_validate_close_contact.auth_seq_id_2    256 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.15 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 "O3'" B DT 2  ? ? P     B DA 3  ? ? "O5'" B DA 3  ? ? 82.42  104.00 -21.58 1.90 Y 
2  1 "O3'" B DT 2  ? ? P     B DA 3  ? ? OP1   B DA 3  ? ? 119.86 110.50 9.36   1.10 Y 
3  1 "O5'" B DA 3  ? ? P     B DA 3  ? ? OP1   B DA 3  ? ? 126.75 110.70 16.05  1.20 N 
4  1 "O4'" B DA 3  ? ? "C1'" B DA 3  ? ? N9    B DA 3  ? ? 103.57 108.00 -4.43  0.70 N 
5  1 "O3'" B DG 7  ? ? P     B DG 8  ? ? OP2   B DG 8  ? ? 118.66 110.50 8.16   1.10 Y 
6  1 "O4'" B DG 8  ? ? "C1'" B DG 8  ? ? N9    B DG 8  ? ? 110.64 108.30 2.34   0.30 N 
7  1 "O3'" B DA 15 ? ? P     B DG 16 ? ? "O5'" B DG 16 ? ? 90.04  104.00 -13.96 1.90 Y 
8  1 "O3'" D DT 2  ? ? P     D DA 3  ? ? "O5'" D DA 3  ? ? 81.98  104.00 -22.02 1.90 Y 
9  1 "O5'" D DA 3  ? ? P     D DA 3  ? ? OP2   D DA 3  ? ? 119.68 110.70 8.98   1.20 N 
10 1 "O4'" D DA 3  ? ? "C1'" D DA 3  ? ? N9    D DA 3  ? ? 110.69 108.30 2.39   0.30 N 
11 1 "O5'" D DG 7  ? ? "C5'" D DG 7  ? ? "C4'" D DG 7  ? ? 104.29 109.40 -5.11  0.80 N 
12 1 "O3'" D DG 7  ? ? P     D DC 8  ? ? OP1   D DC 8  ? ? 86.58  105.20 -18.62 2.20 Y 
13 1 "O4'" D DT 13 ? ? "C1'" D DT 13 ? ? N1    D DT 13 ? ? 110.97 108.30 2.67   0.30 N 
14 1 "O4'" D DA 15 ? ? "C1'" D DA 15 ? ? N9    D DA 15 ? ? 112.27 108.30 3.97   0.30 N 
15 1 "O4'" D DG 16 ? ? "C1'" D DG 16 ? ? N9    D DG 16 ? ? 102.38 108.00 -5.62  0.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PRO A 232 ? ? -43.10 -13.02 
2 1 ARG A 233 ? ? 75.20  131.77 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     233 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.083 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined 9.2330  5.3055  2.6551  0.2045 ? 0.0214  ? 0.0880 ? 0.1647 ? -0.0280 ? 0.0509 ? 1.3239 ? 0.8568 ? 
-2.6015 ? 1.2448 ? -1.6621 ? 5.7477 ? 0.0804 ? -0.0444 ? 0.0805  ? 0.0290 ? 0.0388  ? 0.0530  ? -0.1782 ? 0.0593  ? -0.1192 ? 
2 'X-RAY DIFFRACTION' ? refined 9.0684  7.4367  3.5167  0.1478 ? -0.0367 ? 0.0882 ? 0.1349 ? -0.0573 ? 0.0772 ? 1.3218 ? 0.7112 ? 
-2.1638 ? 1.4242 ? -2.2937 ? 6.1813 ? 0.0292 ? -0.1316 ? 0.0953  ? 0.1128 ? 0.0662  ? 0.0445  ? 0.0991  ? -0.0352 ? -0.0953 ? 
3 'X-RAY DIFFRACTION' ? refined 5.9527  -6.1044 15.4190 0.1164 ? 0.0510  ? 0.0395 ? 0.0894 ? 0.0313  ? 0.0760 ? 4.0161 ? 1.7913 ? 
-1.6931 ? 6.8742 ? 0.5295  ? 3.6491 ? 0.0601 ? -0.3716 ? -0.1950 ? 0.3659 ? -0.0010 ? -0.4400 ? 0.1117  ? 0.2494  ? -0.0591 ? 
4 'X-RAY DIFFRACTION' ? refined 16.9339 17.7246 -7.1105 0.1216 ? -0.0605 ? 0.0694 ? 0.0657 ? -0.0094 ? 0.1099 ? 4.7348 ? 0.2181 ? 
1.0839  ? 6.9476 ? -0.7103 ? 3.6211 ? 0.0879 ? -0.0649 ? 0.2248  ? 0.2557 ? -0.2809 ? -0.4648 ? -0.0635 ? 0.2950  ? 0.1930  ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 ? ? B 1   ? ? ? B 16  ? ? ? 
2 'X-RAY DIFFRACTION' 2 ? ? D 1   ? ? ? D 16  ? ? ? 
3 'X-RAY DIFFRACTION' 3 ? ? A 232 ? ? ? A 293 ? ? ? 
4 'X-RAY DIFFRACTION' 4 ? ? E 230 ? ? ? E 292 ? ? ? 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
DA  OP3    O N N 74  
DA  P      P N N 75  
DA  OP1    O N N 76  
DA  OP2    O N N 77  
DA  "O5'"  O N N 78  
DA  "C5'"  C N N 79  
DA  "C4'"  C N R 80  
DA  "O4'"  O N N 81  
DA  "C3'"  C N S 82  
DA  "O3'"  O N N 83  
DA  "C2'"  C N N 84  
DA  "C1'"  C N R 85  
DA  N9     N Y N 86  
DA  C8     C Y N 87  
DA  N7     N Y N 88  
DA  C5     C Y N 89  
DA  C6     C Y N 90  
DA  N6     N N N 91  
DA  N1     N Y N 92  
DA  C2     C Y N 93  
DA  N3     N Y N 94  
DA  C4     C Y N 95  
DA  HOP3   H N N 96  
DA  HOP2   H N N 97  
DA  "H5'"  H N N 98  
DA  "H5''" H N N 99  
DA  "H4'"  H N N 100 
DA  "H3'"  H N N 101 
DA  "HO3'" H N N 102 
DA  "H2'"  H N N 103 
DA  "H2''" H N N 104 
DA  "H1'"  H N N 105 
DA  H8     H N N 106 
DA  H61    H N N 107 
DA  H62    H N N 108 
DA  H2     H N N 109 
DC  OP3    O N N 110 
DC  P      P N N 111 
DC  OP1    O N N 112 
DC  OP2    O N N 113 
DC  "O5'"  O N N 114 
DC  "C5'"  C N N 115 
DC  "C4'"  C N R 116 
DC  "O4'"  O N N 117 
DC  "C3'"  C N S 118 
DC  "O3'"  O N N 119 
DC  "C2'"  C N N 120 
DC  "C1'"  C N R 121 
DC  N1     N N N 122 
DC  C2     C N N 123 
DC  O2     O N N 124 
DC  N3     N N N 125 
DC  C4     C N N 126 
DC  N4     N N N 127 
DC  C5     C N N 128 
DC  C6     C N N 129 
DC  HOP3   H N N 130 
DC  HOP2   H N N 131 
DC  "H5'"  H N N 132 
DC  "H5''" H N N 133 
DC  "H4'"  H N N 134 
DC  "H3'"  H N N 135 
DC  "HO3'" H N N 136 
DC  "H2'"  H N N 137 
DC  "H2''" H N N 138 
DC  "H1'"  H N N 139 
DC  H41    H N N 140 
DC  H42    H N N 141 
DC  H5     H N N 142 
DC  H6     H N N 143 
DG  OP3    O N N 144 
DG  P      P N N 145 
DG  OP1    O N N 146 
DG  OP2    O N N 147 
DG  "O5'"  O N N 148 
DG  "C5'"  C N N 149 
DG  "C4'"  C N R 150 
DG  "O4'"  O N N 151 
DG  "C3'"  C N S 152 
DG  "O3'"  O N N 153 
DG  "C2'"  C N N 154 
DG  "C1'"  C N R 155 
DG  N9     N Y N 156 
DG  C8     C Y N 157 
DG  N7     N Y N 158 
DG  C5     C Y N 159 
DG  C6     C N N 160 
DG  O6     O N N 161 
DG  N1     N N N 162 
DG  C2     C N N 163 
DG  N2     N N N 164 
DG  N3     N N N 165 
DG  C4     C Y N 166 
DG  HOP3   H N N 167 
DG  HOP2   H N N 168 
DG  "H5'"  H N N 169 
DG  "H5''" H N N 170 
DG  "H4'"  H N N 171 
DG  "H3'"  H N N 172 
DG  "HO3'" H N N 173 
DG  "H2'"  H N N 174 
DG  "H2''" H N N 175 
DG  "H1'"  H N N 176 
DG  H8     H N N 177 
DG  H1     H N N 178 
DG  H21    H N N 179 
DG  H22    H N N 180 
DT  OP3    O N N 181 
DT  P      P N N 182 
DT  OP1    O N N 183 
DT  OP2    O N N 184 
DT  "O5'"  O N N 185 
DT  "C5'"  C N N 186 
DT  "C4'"  C N R 187 
DT  "O4'"  O N N 188 
DT  "C3'"  C N S 189 
DT  "O3'"  O N N 190 
DT  "C2'"  C N N 191 
DT  "C1'"  C N R 192 
DT  N1     N N N 193 
DT  C2     C N N 194 
DT  O2     O N N 195 
DT  N3     N N N 196 
DT  C4     C N N 197 
DT  O4     O N N 198 
DT  C5     C N N 199 
DT  C7     C N N 200 
DT  C6     C N N 201 
DT  HOP3   H N N 202 
DT  HOP2   H N N 203 
DT  "H5'"  H N N 204 
DT  "H5''" H N N 205 
DT  "H4'"  H N N 206 
DT  "H3'"  H N N 207 
DT  "HO3'" H N N 208 
DT  "H2'"  H N N 209 
DT  "H2''" H N N 210 
DT  "H1'"  H N N 211 
DT  H3     H N N 212 
DT  H71    H N N 213 
DT  H72    H N N 214 
DT  H73    H N N 215 
DT  H6     H N N 216 
GLN N      N N N 217 
GLN CA     C N S 218 
GLN C      C N N 219 
GLN O      O N N 220 
GLN CB     C N N 221 
GLN CG     C N N 222 
GLN CD     C N N 223 
GLN OE1    O N N 224 
GLN NE2    N N N 225 
GLN OXT    O N N 226 
GLN H      H N N 227 
GLN H2     H N N 228 
GLN HA     H N N 229 
GLN HB2    H N N 230 
GLN HB3    H N N 231 
GLN HG2    H N N 232 
GLN HG3    H N N 233 
GLN HE21   H N N 234 
GLN HE22   H N N 235 
GLN HXT    H N N 236 
GLU N      N N N 237 
GLU CA     C N S 238 
GLU C      C N N 239 
GLU O      O N N 240 
GLU CB     C N N 241 
GLU CG     C N N 242 
GLU CD     C N N 243 
GLU OE1    O N N 244 
GLU OE2    O N N 245 
GLU OXT    O N N 246 
GLU H      H N N 247 
GLU H2     H N N 248 
GLU HA     H N N 249 
GLU HB2    H N N 250 
GLU HB3    H N N 251 
GLU HG2    H N N 252 
GLU HG3    H N N 253 
GLU HE2    H N N 254 
GLU HXT    H N N 255 
GLY N      N N N 256 
GLY CA     C N N 257 
GLY C      C N N 258 
GLY O      O N N 259 
GLY OXT    O N N 260 
GLY H      H N N 261 
GLY H2     H N N 262 
GLY HA2    H N N 263 
GLY HA3    H N N 264 
GLY HXT    H N N 265 
HIS N      N N N 266 
HIS CA     C N S 267 
HIS C      C N N 268 
HIS O      O N N 269 
HIS CB     C N N 270 
HIS CG     C Y N 271 
HIS ND1    N Y N 272 
HIS CD2    C Y N 273 
HIS CE1    C Y N 274 
HIS NE2    N Y N 275 
HIS OXT    O N N 276 
HIS H      H N N 277 
HIS H2     H N N 278 
HIS HA     H N N 279 
HIS HB2    H N N 280 
HIS HB3    H N N 281 
HIS HD1    H N N 282 
HIS HD2    H N N 283 
HIS HE1    H N N 284 
HIS HE2    H N N 285 
HIS HXT    H N N 286 
HOH O      O N N 287 
HOH H1     H N N 288 
HOH H2     H N N 289 
LEU N      N N N 290 
LEU CA     C N S 291 
LEU C      C N N 292 
LEU O      O N N 293 
LEU CB     C N N 294 
LEU CG     C N N 295 
LEU CD1    C N N 296 
LEU CD2    C N N 297 
LEU OXT    O N N 298 
LEU H      H N N 299 
LEU H2     H N N 300 
LEU HA     H N N 301 
LEU HB2    H N N 302 
LEU HB3    H N N 303 
LEU HG     H N N 304 
LEU HD11   H N N 305 
LEU HD12   H N N 306 
LEU HD13   H N N 307 
LEU HD21   H N N 308 
LEU HD22   H N N 309 
LEU HD23   H N N 310 
LEU HXT    H N N 311 
LYS N      N N N 312 
LYS CA     C N S 313 
LYS C      C N N 314 
LYS O      O N N 315 
LYS CB     C N N 316 
LYS CG     C N N 317 
LYS CD     C N N 318 
LYS CE     C N N 319 
LYS NZ     N N N 320 
LYS OXT    O N N 321 
LYS H      H N N 322 
LYS H2     H N N 323 
LYS HA     H N N 324 
LYS HB2    H N N 325 
LYS HB3    H N N 326 
LYS HG2    H N N 327 
LYS HG3    H N N 328 
LYS HD2    H N N 329 
LYS HD3    H N N 330 
LYS HE2    H N N 331 
LYS HE3    H N N 332 
LYS HZ1    H N N 333 
LYS HZ2    H N N 334 
LYS HZ3    H N N 335 
LYS HXT    H N N 336 
MET N      N N N 337 
MET CA     C N S 338 
MET C      C N N 339 
MET O      O N N 340 
MET CB     C N N 341 
MET CG     C N N 342 
MET SD     S N N 343 
MET CE     C N N 344 
MET OXT    O N N 345 
MET H      H N N 346 
MET H2     H N N 347 
MET HA     H N N 348 
MET HB2    H N N 349 
MET HB3    H N N 350 
MET HG2    H N N 351 
MET HG3    H N N 352 
MET HE1    H N N 353 
MET HE2    H N N 354 
MET HE3    H N N 355 
MET HXT    H N N 356 
PHE N      N N N 357 
PHE CA     C N S 358 
PHE C      C N N 359 
PHE O      O N N 360 
PHE CB     C N N 361 
PHE CG     C Y N 362 
PHE CD1    C Y N 363 
PHE CD2    C Y N 364 
PHE CE1    C Y N 365 
PHE CE2    C Y N 366 
PHE CZ     C Y N 367 
PHE OXT    O N N 368 
PHE H      H N N 369 
PHE H2     H N N 370 
PHE HA     H N N 371 
PHE HB2    H N N 372 
PHE HB3    H N N 373 
PHE HD1    H N N 374 
PHE HD2    H N N 375 
PHE HE1    H N N 376 
PHE HE2    H N N 377 
PHE HZ     H N N 378 
PHE HXT    H N N 379 
PRO N      N N N 380 
PRO CA     C N S 381 
PRO C      C N N 382 
PRO O      O N N 383 
PRO CB     C N N 384 
PRO CG     C N N 385 
PRO CD     C N N 386 
PRO OXT    O N N 387 
PRO H      H N N 388 
PRO HA     H N N 389 
PRO HB2    H N N 390 
PRO HB3    H N N 391 
PRO HG2    H N N 392 
PRO HG3    H N N 393 
PRO HD2    H N N 394 
PRO HD3    H N N 395 
PRO HXT    H N N 396 
SER N      N N N 397 
SER CA     C N S 398 
SER C      C N N 399 
SER O      O N N 400 
SER CB     C N N 401 
SER OG     O N N 402 
SER OXT    O N N 403 
SER H      H N N 404 
SER H2     H N N 405 
SER HA     H N N 406 
SER HB2    H N N 407 
SER HB3    H N N 408 
SER HG     H N N 409 
SER HXT    H N N 410 
THR N      N N N 411 
THR CA     C N S 412 
THR C      C N N 413 
THR O      O N N 414 
THR CB     C N R 415 
THR OG1    O N N 416 
THR CG2    C N N 417 
THR OXT    O N N 418 
THR H      H N N 419 
THR H2     H N N 420 
THR HA     H N N 421 
THR HB     H N N 422 
THR HG1    H N N 423 
THR HG21   H N N 424 
THR HG22   H N N 425 
THR HG23   H N N 426 
THR HXT    H N N 427 
TRP N      N N N 428 
TRP CA     C N S 429 
TRP C      C N N 430 
TRP O      O N N 431 
TRP CB     C N N 432 
TRP CG     C Y N 433 
TRP CD1    C Y N 434 
TRP CD2    C Y N 435 
TRP NE1    N Y N 436 
TRP CE2    C Y N 437 
TRP CE3    C Y N 438 
TRP CZ2    C Y N 439 
TRP CZ3    C Y N 440 
TRP CH2    C Y N 441 
TRP OXT    O N N 442 
TRP H      H N N 443 
TRP H2     H N N 444 
TRP HA     H N N 445 
TRP HB2    H N N 446 
TRP HB3    H N N 447 
TRP HD1    H N N 448 
TRP HE1    H N N 449 
TRP HE3    H N N 450 
TRP HZ2    H N N 451 
TRP HZ3    H N N 452 
TRP HH2    H N N 453 
TRP HXT    H N N 454 
TYR N      N N N 455 
TYR CA     C N S 456 
TYR C      C N N 457 
TYR O      O N N 458 
TYR CB     C N N 459 
TYR CG     C Y N 460 
TYR CD1    C Y N 461 
TYR CD2    C Y N 462 
TYR CE1    C Y N 463 
TYR CE2    C Y N 464 
TYR CZ     C Y N 465 
TYR OH     O N N 466 
TYR OXT    O N N 467 
TYR H      H N N 468 
TYR H2     H N N 469 
TYR HA     H N N 470 
TYR HB2    H N N 471 
TYR HB3    H N N 472 
TYR HD1    H N N 473 
TYR HD2    H N N 474 
TYR HE1    H N N 475 
TYR HE2    H N N 476 
TYR HH     H N N 477 
TYR HXT    H N N 478 
VAL N      N N N 479 
VAL CA     C N S 480 
VAL C      C N N 481 
VAL O      O N N 482 
VAL CB     C N N 483 
VAL CG1    C N N 484 
VAL CG2    C N N 485 
VAL OXT    O N N 486 
VAL H      H N N 487 
VAL H2     H N N 488 
VAL HA     H N N 489 
VAL HB     H N N 490 
VAL HG11   H N N 491 
VAL HG12   H N N 492 
VAL HG13   H N N 493 
VAL HG21   H N N 494 
VAL HG22   H N N 495 
VAL HG23   H N N 496 
VAL HXT    H N N 497 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
DA  OP3   P      sing N N 70  
DA  OP3   HOP3   sing N N 71  
DA  P     OP1    doub N N 72  
DA  P     OP2    sing N N 73  
DA  P     "O5'"  sing N N 74  
DA  OP2   HOP2   sing N N 75  
DA  "O5'" "C5'"  sing N N 76  
DA  "C5'" "C4'"  sing N N 77  
DA  "C5'" "H5'"  sing N N 78  
DA  "C5'" "H5''" sing N N 79  
DA  "C4'" "O4'"  sing N N 80  
DA  "C4'" "C3'"  sing N N 81  
DA  "C4'" "H4'"  sing N N 82  
DA  "O4'" "C1'"  sing N N 83  
DA  "C3'" "O3'"  sing N N 84  
DA  "C3'" "C2'"  sing N N 85  
DA  "C3'" "H3'"  sing N N 86  
DA  "O3'" "HO3'" sing N N 87  
DA  "C2'" "C1'"  sing N N 88  
DA  "C2'" "H2'"  sing N N 89  
DA  "C2'" "H2''" sing N N 90  
DA  "C1'" N9     sing N N 91  
DA  "C1'" "H1'"  sing N N 92  
DA  N9    C8     sing Y N 93  
DA  N9    C4     sing Y N 94  
DA  C8    N7     doub Y N 95  
DA  C8    H8     sing N N 96  
DA  N7    C5     sing Y N 97  
DA  C5    C6     sing Y N 98  
DA  C5    C4     doub Y N 99  
DA  C6    N6     sing N N 100 
DA  C6    N1     doub Y N 101 
DA  N6    H61    sing N N 102 
DA  N6    H62    sing N N 103 
DA  N1    C2     sing Y N 104 
DA  C2    N3     doub Y N 105 
DA  C2    H2     sing N N 106 
DA  N3    C4     sing Y N 107 
DC  OP3   P      sing N N 108 
DC  OP3   HOP3   sing N N 109 
DC  P     OP1    doub N N 110 
DC  P     OP2    sing N N 111 
DC  P     "O5'"  sing N N 112 
DC  OP2   HOP2   sing N N 113 
DC  "O5'" "C5'"  sing N N 114 
DC  "C5'" "C4'"  sing N N 115 
DC  "C5'" "H5'"  sing N N 116 
DC  "C5'" "H5''" sing N N 117 
DC  "C4'" "O4'"  sing N N 118 
DC  "C4'" "C3'"  sing N N 119 
DC  "C4'" "H4'"  sing N N 120 
DC  "O4'" "C1'"  sing N N 121 
DC  "C3'" "O3'"  sing N N 122 
DC  "C3'" "C2'"  sing N N 123 
DC  "C3'" "H3'"  sing N N 124 
DC  "O3'" "HO3'" sing N N 125 
DC  "C2'" "C1'"  sing N N 126 
DC  "C2'" "H2'"  sing N N 127 
DC  "C2'" "H2''" sing N N 128 
DC  "C1'" N1     sing N N 129 
DC  "C1'" "H1'"  sing N N 130 
DC  N1    C2     sing N N 131 
DC  N1    C6     sing N N 132 
DC  C2    O2     doub N N 133 
DC  C2    N3     sing N N 134 
DC  N3    C4     doub N N 135 
DC  C4    N4     sing N N 136 
DC  C4    C5     sing N N 137 
DC  N4    H41    sing N N 138 
DC  N4    H42    sing N N 139 
DC  C5    C6     doub N N 140 
DC  C5    H5     sing N N 141 
DC  C6    H6     sing N N 142 
DG  OP3   P      sing N N 143 
DG  OP3   HOP3   sing N N 144 
DG  P     OP1    doub N N 145 
DG  P     OP2    sing N N 146 
DG  P     "O5'"  sing N N 147 
DG  OP2   HOP2   sing N N 148 
DG  "O5'" "C5'"  sing N N 149 
DG  "C5'" "C4'"  sing N N 150 
DG  "C5'" "H5'"  sing N N 151 
DG  "C5'" "H5''" sing N N 152 
DG  "C4'" "O4'"  sing N N 153 
DG  "C4'" "C3'"  sing N N 154 
DG  "C4'" "H4'"  sing N N 155 
DG  "O4'" "C1'"  sing N N 156 
DG  "C3'" "O3'"  sing N N 157 
DG  "C3'" "C2'"  sing N N 158 
DG  "C3'" "H3'"  sing N N 159 
DG  "O3'" "HO3'" sing N N 160 
DG  "C2'" "C1'"  sing N N 161 
DG  "C2'" "H2'"  sing N N 162 
DG  "C2'" "H2''" sing N N 163 
DG  "C1'" N9     sing N N 164 
DG  "C1'" "H1'"  sing N N 165 
DG  N9    C8     sing Y N 166 
DG  N9    C4     sing Y N 167 
DG  C8    N7     doub Y N 168 
DG  C8    H8     sing N N 169 
DG  N7    C5     sing Y N 170 
DG  C5    C6     sing N N 171 
DG  C5    C4     doub Y N 172 
DG  C6    O6     doub N N 173 
DG  C6    N1     sing N N 174 
DG  N1    C2     sing N N 175 
DG  N1    H1     sing N N 176 
DG  C2    N2     sing N N 177 
DG  C2    N3     doub N N 178 
DG  N2    H21    sing N N 179 
DG  N2    H22    sing N N 180 
DG  N3    C4     sing N N 181 
DT  OP3   P      sing N N 182 
DT  OP3   HOP3   sing N N 183 
DT  P     OP1    doub N N 184 
DT  P     OP2    sing N N 185 
DT  P     "O5'"  sing N N 186 
DT  OP2   HOP2   sing N N 187 
DT  "O5'" "C5'"  sing N N 188 
DT  "C5'" "C4'"  sing N N 189 
DT  "C5'" "H5'"  sing N N 190 
DT  "C5'" "H5''" sing N N 191 
DT  "C4'" "O4'"  sing N N 192 
DT  "C4'" "C3'"  sing N N 193 
DT  "C4'" "H4'"  sing N N 194 
DT  "O4'" "C1'"  sing N N 195 
DT  "C3'" "O3'"  sing N N 196 
DT  "C3'" "C2'"  sing N N 197 
DT  "C3'" "H3'"  sing N N 198 
DT  "O3'" "HO3'" sing N N 199 
DT  "C2'" "C1'"  sing N N 200 
DT  "C2'" "H2'"  sing N N 201 
DT  "C2'" "H2''" sing N N 202 
DT  "C1'" N1     sing N N 203 
DT  "C1'" "H1'"  sing N N 204 
DT  N1    C2     sing N N 205 
DT  N1    C6     sing N N 206 
DT  C2    O2     doub N N 207 
DT  C2    N3     sing N N 208 
DT  N3    C4     sing N N 209 
DT  N3    H3     sing N N 210 
DT  C4    O4     doub N N 211 
DT  C4    C5     sing N N 212 
DT  C5    C7     sing N N 213 
DT  C5    C6     doub N N 214 
DT  C7    H71    sing N N 215 
DT  C7    H72    sing N N 216 
DT  C7    H73    sing N N 217 
DT  C6    H6     sing N N 218 
GLN N     CA     sing N N 219 
GLN N     H      sing N N 220 
GLN N     H2     sing N N 221 
GLN CA    C      sing N N 222 
GLN CA    CB     sing N N 223 
GLN CA    HA     sing N N 224 
GLN C     O      doub N N 225 
GLN C     OXT    sing N N 226 
GLN CB    CG     sing N N 227 
GLN CB    HB2    sing N N 228 
GLN CB    HB3    sing N N 229 
GLN CG    CD     sing N N 230 
GLN CG    HG2    sing N N 231 
GLN CG    HG3    sing N N 232 
GLN CD    OE1    doub N N 233 
GLN CD    NE2    sing N N 234 
GLN NE2   HE21   sing N N 235 
GLN NE2   HE22   sing N N 236 
GLN OXT   HXT    sing N N 237 
GLU N     CA     sing N N 238 
GLU N     H      sing N N 239 
GLU N     H2     sing N N 240 
GLU CA    C      sing N N 241 
GLU CA    CB     sing N N 242 
GLU CA    HA     sing N N 243 
GLU C     O      doub N N 244 
GLU C     OXT    sing N N 245 
GLU CB    CG     sing N N 246 
GLU CB    HB2    sing N N 247 
GLU CB    HB3    sing N N 248 
GLU CG    CD     sing N N 249 
GLU CG    HG2    sing N N 250 
GLU CG    HG3    sing N N 251 
GLU CD    OE1    doub N N 252 
GLU CD    OE2    sing N N 253 
GLU OE2   HE2    sing N N 254 
GLU OXT   HXT    sing N N 255 
GLY N     CA     sing N N 256 
GLY N     H      sing N N 257 
GLY N     H2     sing N N 258 
GLY CA    C      sing N N 259 
GLY CA    HA2    sing N N 260 
GLY CA    HA3    sing N N 261 
GLY C     O      doub N N 262 
GLY C     OXT    sing N N 263 
GLY OXT   HXT    sing N N 264 
HIS N     CA     sing N N 265 
HIS N     H      sing N N 266 
HIS N     H2     sing N N 267 
HIS CA    C      sing N N 268 
HIS CA    CB     sing N N 269 
HIS CA    HA     sing N N 270 
HIS C     O      doub N N 271 
HIS C     OXT    sing N N 272 
HIS CB    CG     sing N N 273 
HIS CB    HB2    sing N N 274 
HIS CB    HB3    sing N N 275 
HIS CG    ND1    sing Y N 276 
HIS CG    CD2    doub Y N 277 
HIS ND1   CE1    doub Y N 278 
HIS ND1   HD1    sing N N 279 
HIS CD2   NE2    sing Y N 280 
HIS CD2   HD2    sing N N 281 
HIS CE1   NE2    sing Y N 282 
HIS CE1   HE1    sing N N 283 
HIS NE2   HE2    sing N N 284 
HIS OXT   HXT    sing N N 285 
HOH O     H1     sing N N 286 
HOH O     H2     sing N N 287 
LEU N     CA     sing N N 288 
LEU N     H      sing N N 289 
LEU N     H2     sing N N 290 
LEU CA    C      sing N N 291 
LEU CA    CB     sing N N 292 
LEU CA    HA     sing N N 293 
LEU C     O      doub N N 294 
LEU C     OXT    sing N N 295 
LEU CB    CG     sing N N 296 
LEU CB    HB2    sing N N 297 
LEU CB    HB3    sing N N 298 
LEU CG    CD1    sing N N 299 
LEU CG    CD2    sing N N 300 
LEU CG    HG     sing N N 301 
LEU CD1   HD11   sing N N 302 
LEU CD1   HD12   sing N N 303 
LEU CD1   HD13   sing N N 304 
LEU CD2   HD21   sing N N 305 
LEU CD2   HD22   sing N N 306 
LEU CD2   HD23   sing N N 307 
LEU OXT   HXT    sing N N 308 
LYS N     CA     sing N N 309 
LYS N     H      sing N N 310 
LYS N     H2     sing N N 311 
LYS CA    C      sing N N 312 
LYS CA    CB     sing N N 313 
LYS CA    HA     sing N N 314 
LYS C     O      doub N N 315 
LYS C     OXT    sing N N 316 
LYS CB    CG     sing N N 317 
LYS CB    HB2    sing N N 318 
LYS CB    HB3    sing N N 319 
LYS CG    CD     sing N N 320 
LYS CG    HG2    sing N N 321 
LYS CG    HG3    sing N N 322 
LYS CD    CE     sing N N 323 
LYS CD    HD2    sing N N 324 
LYS CD    HD3    sing N N 325 
LYS CE    NZ     sing N N 326 
LYS CE    HE2    sing N N 327 
LYS CE    HE3    sing N N 328 
LYS NZ    HZ1    sing N N 329 
LYS NZ    HZ2    sing N N 330 
LYS NZ    HZ3    sing N N 331 
LYS OXT   HXT    sing N N 332 
MET N     CA     sing N N 333 
MET N     H      sing N N 334 
MET N     H2     sing N N 335 
MET CA    C      sing N N 336 
MET CA    CB     sing N N 337 
MET CA    HA     sing N N 338 
MET C     O      doub N N 339 
MET C     OXT    sing N N 340 
MET CB    CG     sing N N 341 
MET CB    HB2    sing N N 342 
MET CB    HB3    sing N N 343 
MET CG    SD     sing N N 344 
MET CG    HG2    sing N N 345 
MET CG    HG3    sing N N 346 
MET SD    CE     sing N N 347 
MET CE    HE1    sing N N 348 
MET CE    HE2    sing N N 349 
MET CE    HE3    sing N N 350 
MET OXT   HXT    sing N N 351 
PHE N     CA     sing N N 352 
PHE N     H      sing N N 353 
PHE N     H2     sing N N 354 
PHE CA    C      sing N N 355 
PHE CA    CB     sing N N 356 
PHE CA    HA     sing N N 357 
PHE C     O      doub N N 358 
PHE C     OXT    sing N N 359 
PHE CB    CG     sing N N 360 
PHE CB    HB2    sing N N 361 
PHE CB    HB3    sing N N 362 
PHE CG    CD1    doub Y N 363 
PHE CG    CD2    sing Y N 364 
PHE CD1   CE1    sing Y N 365 
PHE CD1   HD1    sing N N 366 
PHE CD2   CE2    doub Y N 367 
PHE CD2   HD2    sing N N 368 
PHE CE1   CZ     doub Y N 369 
PHE CE1   HE1    sing N N 370 
PHE CE2   CZ     sing Y N 371 
PHE CE2   HE2    sing N N 372 
PHE CZ    HZ     sing N N 373 
PHE OXT   HXT    sing N N 374 
PRO N     CA     sing N N 375 
PRO N     CD     sing N N 376 
PRO N     H      sing N N 377 
PRO CA    C      sing N N 378 
PRO CA    CB     sing N N 379 
PRO CA    HA     sing N N 380 
PRO C     O      doub N N 381 
PRO C     OXT    sing N N 382 
PRO CB    CG     sing N N 383 
PRO CB    HB2    sing N N 384 
PRO CB    HB3    sing N N 385 
PRO CG    CD     sing N N 386 
PRO CG    HG2    sing N N 387 
PRO CG    HG3    sing N N 388 
PRO CD    HD2    sing N N 389 
PRO CD    HD3    sing N N 390 
PRO OXT   HXT    sing N N 391 
SER N     CA     sing N N 392 
SER N     H      sing N N 393 
SER N     H2     sing N N 394 
SER CA    C      sing N N 395 
SER CA    CB     sing N N 396 
SER CA    HA     sing N N 397 
SER C     O      doub N N 398 
SER C     OXT    sing N N 399 
SER CB    OG     sing N N 400 
SER CB    HB2    sing N N 401 
SER CB    HB3    sing N N 402 
SER OG    HG     sing N N 403 
SER OXT   HXT    sing N N 404 
THR N     CA     sing N N 405 
THR N     H      sing N N 406 
THR N     H2     sing N N 407 
THR CA    C      sing N N 408 
THR CA    CB     sing N N 409 
THR CA    HA     sing N N 410 
THR C     O      doub N N 411 
THR C     OXT    sing N N 412 
THR CB    OG1    sing N N 413 
THR CB    CG2    sing N N 414 
THR CB    HB     sing N N 415 
THR OG1   HG1    sing N N 416 
THR CG2   HG21   sing N N 417 
THR CG2   HG22   sing N N 418 
THR CG2   HG23   sing N N 419 
THR OXT   HXT    sing N N 420 
TRP N     CA     sing N N 421 
TRP N     H      sing N N 422 
TRP N     H2     sing N N 423 
TRP CA    C      sing N N 424 
TRP CA    CB     sing N N 425 
TRP CA    HA     sing N N 426 
TRP C     O      doub N N 427 
TRP C     OXT    sing N N 428 
TRP CB    CG     sing N N 429 
TRP CB    HB2    sing N N 430 
TRP CB    HB3    sing N N 431 
TRP CG    CD1    doub Y N 432 
TRP CG    CD2    sing Y N 433 
TRP CD1   NE1    sing Y N 434 
TRP CD1   HD1    sing N N 435 
TRP CD2   CE2    doub Y N 436 
TRP CD2   CE3    sing Y N 437 
TRP NE1   CE2    sing Y N 438 
TRP NE1   HE1    sing N N 439 
TRP CE2   CZ2    sing Y N 440 
TRP CE3   CZ3    doub Y N 441 
TRP CE3   HE3    sing N N 442 
TRP CZ2   CH2    doub Y N 443 
TRP CZ2   HZ2    sing N N 444 
TRP CZ3   CH2    sing Y N 445 
TRP CZ3   HZ3    sing N N 446 
TRP CH2   HH2    sing N N 447 
TRP OXT   HXT    sing N N 448 
TYR N     CA     sing N N 449 
TYR N     H      sing N N 450 
TYR N     H2     sing N N 451 
TYR CA    C      sing N N 452 
TYR CA    CB     sing N N 453 
TYR CA    HA     sing N N 454 
TYR C     O      doub N N 455 
TYR C     OXT    sing N N 456 
TYR CB    CG     sing N N 457 
TYR CB    HB2    sing N N 458 
TYR CB    HB3    sing N N 459 
TYR CG    CD1    doub Y N 460 
TYR CG    CD2    sing Y N 461 
TYR CD1   CE1    sing Y N 462 
TYR CD1   HD1    sing N N 463 
TYR CD2   CE2    doub Y N 464 
TYR CD2   HD2    sing N N 465 
TYR CE1   CZ     doub Y N 466 
TYR CE1   HE1    sing N N 467 
TYR CE2   CZ     sing Y N 468 
TYR CE2   HE2    sing N N 469 
TYR CZ    OH     sing N N 470 
TYR OH    HH     sing N N 471 
TYR OXT   HXT    sing N N 472 
VAL N     CA     sing N N 473 
VAL N     H      sing N N 474 
VAL N     H2     sing N N 475 
VAL CA    C      sing N N 476 
VAL CA    CB     sing N N 477 
VAL CA    HA     sing N N 478 
VAL C     O      doub N N 479 
VAL C     OXT    sing N N 480 
VAL CB    CG1    sing N N 481 
VAL CB    CG2    sing N N 482 
VAL CB    HB     sing N N 483 
VAL CG1   HG11   sing N N 484 
VAL CG1   HG12   sing N N 485 
VAL CG1   HG13   sing N N 486 
VAL CG2   HG21   sing N N 487 
VAL CG2   HG22   sing N N 488 
VAL CG2   HG23   sing N N 489 
VAL OXT   HXT    sing N N 490 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
8R7F 'double helix'        
8R7F 'b-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 A DC 1  1_555 B DG 16 1_555 0.175  -0.222 0.079  1.749   2.331   -1.293 1  B_DC1:DG16_D B 1  ? D 16 ? 19 1 
1 A DT 2  1_555 B DA 15 1_555 0.001  -0.197 0.029  9.333   -4.073  0.886  2  B_DT2:DA15_D B 2  ? D 15 ? 20 1 
1 A DA 3  1_555 B DT 14 1_555 0.204  0.030  -0.077 1.050   -9.670  4.701  3  B_DA3:DT14_D B 3  ? D 14 ? 20 1 
1 A DA 4  1_555 B DT 13 1_555 0.582  0.086  0.168  0.923   -15.080 6.529  4  B_DA4:DT13_D B 4  ? D 13 ? 20 1 
1 A DA 5  1_555 B DT 12 1_555 0.528  -0.663 0.030  0.734   -12.069 -1.891 5  B_DA5:DT12_D B 5  ? D 12 ? 20 1 
1 A DC 6  1_555 B DG 11 1_555 1.253  -0.281 0.035  -3.933  -11.968 5.190  6  B_DC6:DG11_D B 6  ? D 11 ? 19 1 
1 A DG 7  1_555 B DC 10 1_555 0.421  -0.204 -0.079 2.734   -9.647  -1.238 7  B_DG7:DC10_D B 7  ? D 10 ? 19 1 
1 A DG 8  1_555 B DC 9  1_555 0.183  -0.278 0.073  1.945   -9.168  -2.905 8  B_DG8:DC9_D  B 8  ? D 9  ? 19 1 
1 A DG 9  1_555 B DC 8  1_555 0.362  -0.212 0.145  -1.893  -6.737  0.397  9  B_DG9:DC8_D  B 9  ? D 8  ? 19 1 
1 A DC 10 1_555 B DG 7  1_555 -0.100 -0.322 0.146  -2.718  -6.930  -4.303 10 B_DC10:DG7_D B 10 ? D 7  ? 19 1 
1 A DA 11 1_555 B DT 6  1_555 -0.309 -0.281 0.286  7.427   -13.776 3.076  11 B_DA11:DT6_D B 11 ? D 6  ? 20 1 
1 A DA 12 1_555 B DT 5  1_555 0.372  -0.275 0.123  1.553   -12.135 -2.593 12 B_DA12:DT5_D B 12 ? D 5  ? 20 1 
1 A DT 13 1_555 B DA 4  1_555 -0.144 -0.088 0.296  -1.519  -15.269 6.517  13 B_DT13:DA4_D B 13 ? D 4  ? 20 1 
1 A DT 14 1_555 B DA 3  1_555 0.186  -0.225 0.140  -7.467  -13.313 2.322  14 B_DT14:DA3_D B 14 ? D 3  ? 20 1 
1 A DA 15 1_555 B DT 2  1_555 -0.272 -0.259 -0.335 -10.264 -2.475  2.632  15 B_DA15:DT2_D B 15 ? D 2  ? 20 1 
1 A DG 16 1_555 B DC 1  1_555 0.145  -0.129 0.433  -2.297  -3.037  2.101  16 B_DG16:DC1_D B 16 ? D 1  ? 19 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 A DC 1  1_555 B DG 16 1_555 A DT 2  1_555 B DA 15 1_555 1.507  0.255  2.941 5.774  5.450  35.618 -0.304 -1.655 3.143 8.776  
-9.297 36.464 1  BB_DC1DT2:DA15DG16_DD B 1  ? D 16 ? B 2  ? D 15 ? 
1 A DT 2  1_555 B DA 15 1_555 A DA 3  1_555 B DT 14 1_555 -1.214 0.494  3.479 -4.242 6.043  38.491 -0.056 1.254  3.621 9.066  
6.364  39.166 2  BB_DT2DA3:DT14DA15_DD B 2  ? D 15 ? B 3  ? D 14 ? 
1 A DA 3  1_555 B DT 14 1_555 A DA 4  1_555 B DT 13 1_555 0.027  -0.460 3.239 -1.431 1.781  36.216 -0.984 -0.241 3.210 2.861  
2.299  36.285 3  BB_DA3DA4:DT13DT14_DD B 3  ? D 14 ? B 4  ? D 13 ? 
1 A DA 4  1_555 B DT 13 1_555 A DA 5  1_555 B DT 12 1_555 -0.952 -0.576 3.034 -2.299 2.138  33.671 -1.312 1.291  3.049 3.680  
3.958  33.813 4  BB_DA4DA5:DT12DT13_DD B 4  ? D 13 ? B 5  ? D 12 ? 
1 A DA 5  1_555 B DT 12 1_555 A DC 6  1_555 B DG 11 1_555 0.062  -0.459 3.412 0.083  -1.376 37.546 -0.525 -0.085 3.426 -2.137 
-0.129 37.571 5  BB_DA5DC6:DG11DT12_DD B 5  ? D 12 ? B 6  ? D 11 ? 
1 A DC 6  1_555 B DG 11 1_555 A DG 7  1_555 B DC 10 1_555 -0.430 0.539  3.212 4.163  10.363 25.658 -1.362 1.886  3.087 22.053 
-8.859 27.946 6  BB_DC6DG7:DC10DG11_DD B 6  ? D 11 ? B 7  ? D 10 ? 
1 A DG 7  1_555 B DC 10 1_555 A DG 8  1_555 B DC 9  1_555 0.025  -0.456 3.248 -2.804 7.320  32.202 -2.008 -0.506 3.061 12.958 
4.963  33.118 7  BB_DG7DG8:DC9DC10_DD  B 7  ? D 10 ? B 8  ? D 9  ? 
1 A DG 8  1_555 B DC 9  1_555 A DG 9  1_555 B DC 8  1_555 0.001  -0.594 3.295 0.098  0.813  37.619 -1.027 0.012  3.282 1.261  
-0.151 37.628 8  BB_DG8DG9:DC8DC9_DD   B 8  ? D 9  ? B 9  ? D 8  ? 
1 A DG 9  1_555 B DC 8  1_555 A DC 10 1_555 B DG 7  1_555 -0.452 -0.871 3.312 1.698  3.857  30.485 -2.391 1.181  3.151 7.292  
-3.209 30.768 9  BB_DG9DC10:DG7DC8_DD  B 9  ? D 8  ? B 10 ? D 7  ? 
1 A DC 10 1_555 B DG 7  1_555 A DA 11 1_555 B DT 6  1_555 0.320  0.357  3.091 -1.263 8.900  29.688 -0.979 -0.833 3.052 16.888 
2.396  30.990 10 BB_DC10DA11:DT6DG7_DD B 10 ? D 7  ? B 11 ? D 6  ? 
1 A DA 11 1_555 B DT 6  1_555 A DA 12 1_555 B DT 5  1_555 -0.029 -0.436 3.299 0.405  4.760  37.480 -1.287 0.096  3.221 7.371  
-0.627 37.773 11 BB_DA11DA12:DT5DT6_DD B 11 ? D 6  ? B 12 ? D 5  ? 
1 A DA 12 1_555 B DT 5  1_555 A DT 13 1_555 B DA 4  1_555 0.802  -1.092 3.285 0.370  -0.974 31.430 -1.830 -1.410 3.325 -1.798 
-0.683 31.447 12 BB_DA12DT13:DA4DT5_DD B 12 ? D 5  ? B 13 ? D 4  ? 
1 A DT 13 1_555 B DA 4  1_555 A DT 14 1_555 B DA 3  1_555 -0.374 -0.572 3.382 1.849  1.970  37.376 -1.155 0.830  3.327 3.069  
-2.881 37.470 13 BB_DT13DT14:DA3DA4_DD B 13 ? D 4  ? B 14 ? D 3  ? 
1 A DT 14 1_555 B DA 3  1_555 A DA 15 1_555 B DT 2  1_555 1.133  0.568  3.269 4.178  5.035  34.919 0.171  -1.228 3.424 8.300  
-6.888 35.508 14 BB_DT14DA15:DT2DA3_DD B 14 ? D 3  ? B 15 ? D 2  ? 
1 A DA 15 1_555 B DT 2  1_555 A DG 16 1_555 B DC 1  1_555 -1.584 0.541  3.175 -8.354 2.906  38.126 0.449  1.334  3.463 4.377  
12.583 39.101 15 BB_DA15DG16:DC1DT2_DD B 15 ? D 2  ? B 16 ? D 1  ? 
# 
_pdbx_audit_support.funding_organization   'Swedish Research Council' 
_pdbx_audit_support.country                Sweden 
_pdbx_audit_support.grant_number           C24905003 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8PM5 
_pdbx_initial_refinement_model.details          'monomeric model' 
# 
_atom_sites.entry_id                    8R7F 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.022058 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.008789 
_atom_sites.fract_transf_matrix[2][1]   -0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.015831 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   -0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.020974 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    O "O5'" . DC  A 1 1  ? 5.932   2.580   30.163  1.00 94.34  ? 1   DC  B "O5'" 1 
ATOM   2    C "C5'" . DC  A 1 1  ? 5.373   3.128   28.949  1.00 85.39  ? 1   DC  B "C5'" 1 
ATOM   3    C "C4'" . DC  A 1 1  ? 4.396   2.135   28.375  1.00 79.49  ? 1   DC  B "C4'" 1 
ATOM   4    O "O4'" . DC  A 1 1  ? 3.149   2.803   28.064  1.00 76.02  ? 1   DC  B "O4'" 1 
ATOM   5    C "C3'" . DC  A 1 1  ? 4.857   1.490   27.069  1.00 74.09  ? 1   DC  B "C3'" 1 
ATOM   6    O "O3'" . DC  A 1 1  ? 4.272   0.204   26.886  1.00 76.90  ? 1   DC  B "O3'" 1 
ATOM   7    C "C2'" . DC  A 1 1  ? 4.325   2.493   26.059  1.00 74.42  ? 1   DC  B "C2'" 1 
ATOM   8    C "C1'" . DC  A 1 1  ? 2.995   2.911   26.658  1.00 71.94  ? 1   DC  B "C1'" 1 
ATOM   9    N N1    . DC  A 1 1  ? 2.594   4.302   26.330  1.00 65.55  ? 1   DC  B N1    1 
ATOM   10   C C2    . DC  A 1 1  ? 1.337   4.527   25.745  1.00 66.25  ? 1   DC  B C2    1 
ATOM   11   O O2    . DC  A 1 1  ? 0.595   3.564   25.502  1.00 66.65  ? 1   DC  B O2    1 
ATOM   12   N N3    . DC  A 1 1  ? 0.933   5.794   25.487  1.00 65.28  ? 1   DC  B N3    1 
ATOM   13   C C4    . DC  A 1 1  ? 1.733   6.824   25.778  1.00 74.68  ? 1   DC  B C4    1 
ATOM   14   N N4    . DC  A 1 1  ? 1.275   8.039   25.490  1.00 77.02  ? 1   DC  B N4    1 
ATOM   15   C C5    . DC  A 1 1  ? 3.019   6.620   26.376  1.00 72.75  ? 1   DC  B C5    1 
ATOM   16   C C6    . DC  A 1 1  ? 3.402   5.353   26.635  1.00 69.68  ? 1   DC  B C6    1 
ATOM   17   P P     . DT  A 1 2  ? 4.747   -0.799  25.723  1.00 72.18  ? 2   DT  B P     1 
ATOM   18   O OP1   . DT  A 1 2  ? 4.061   -2.107  25.871  1.00 74.11  ? 2   DT  B OP1   1 
ATOM   19   O OP2   . DT  A 1 2  ? 6.224   -0.806  25.560  1.00 74.47  ? 2   DT  B OP2   1 
ATOM   20   O "O5'" . DT  A 1 2  ? 3.987   -0.156  24.473  1.00 66.90  ? 2   DT  B "O5'" 1 
ATOM   21   C "C5'" . DT  A 1 2  ? 2.659   -0.683  24.219  1.00 65.82  ? 2   DT  B "C5'" 1 
ATOM   22   C "C4'" . DT  A 1 2  ? 2.050   0.071   23.073  1.00 66.59  ? 2   DT  B "C4'" 1 
ATOM   23   O "O4'" . DT  A 1 2  ? 2.070   1.497   23.355  1.00 63.03  ? 2   DT  B "O4'" 1 
ATOM   24   C "C3'" . DT  A 1 2  ? 2.801   -0.130  21.757  1.00 67.56  ? 2   DT  B "C3'" 1 
ATOM   25   O "O3'" . DT  A 1 2  ? 1.882   -0.341  20.690  1.00 61.75  ? 2   DT  B "O3'" 1 
ATOM   26   C "C2'" . DT  A 1 2  ? 3.564   1.185   21.626  1.00 63.28  ? 2   DT  B "C2'" 1 
ATOM   27   C "C1'" . DT  A 1 2  ? 2.508   2.132   22.162  1.00 61.89  ? 2   DT  B "C1'" 1 
ATOM   28   N N1    . DT  A 1 2  ? 2.938   3.501   22.468  1.00 59.06  ? 2   DT  B N1    1 
ATOM   29   C C2    . DT  A 1 2  ? 1.998   4.482   22.248  1.00 68.50  ? 2   DT  B C2    1 
ATOM   30   O O2    . DT  A 1 2  ? 0.864   4.226   21.847  1.00 69.64  ? 2   DT  B O2    1 
ATOM   31   N N3    . DT  A 1 2  ? 2.417   5.756   22.544  1.00 65.17  ? 2   DT  B N3    1 
ATOM   32   C C4    . DT  A 1 2  ? 3.665   6.138   22.992  1.00 67.24  ? 2   DT  B C4    1 
ATOM   33   O O4    . DT  A 1 2  ? 3.897   7.324   23.209  1.00 71.04  ? 2   DT  B O4    1 
ATOM   34   C C5    . DT  A 1 2  ? 4.606   5.063   23.195  1.00 59.44  ? 2   DT  B C5    1 
ATOM   35   C C7    . DT  A 1 2  ? 5.956   5.413   23.737  1.00 58.58  ? 2   DT  B C7    1 
ATOM   36   C C6    . DT  A 1 2  ? 4.199   3.805   22.955  1.00 58.35  ? 2   DT  B C6    1 
ATOM   37   P P     . DA  A 1 3  ? 1.836   -1.742  19.900  1.00 60.30  ? 3   DA  B P     1 
ATOM   38   O OP1   . DA  A 1 3  ? 1.698   -3.020  20.660  1.00 59.05  ? 3   DA  B OP1   1 
ATOM   39   O OP2   . DA  A 1 3  ? 3.059   -1.633  19.055  1.00 69.67  ? 3   DA  B OP2   1 
ATOM   40   O "O5'" . DA  A 1 3  ? 0.695   -0.996  19.072  1.00 53.35  ? 3   DA  B "O5'" 1 
ATOM   41   C "C5'" . DA  A 1 3  ? -0.691  -1.108  19.345  1.00 55.60  ? 3   DA  B "C5'" 1 
ATOM   42   C "C4'" . DA  A 1 3  ? -1.405  -0.145  18.410  1.00 61.16  ? 3   DA  B "C4'" 1 
ATOM   43   O "O4'" . DA  A 1 3  ? -1.000  1.212   18.719  1.00 56.49  ? 3   DA  B "O4'" 1 
ATOM   44   C "C3'" . DA  A 1 3  ? -1.168  -0.303  16.904  1.00 59.95  ? 3   DA  B "C3'" 1 
ATOM   45   O "O3'" . DA  A 1 3  ? -2.361  0.030   16.198  1.00 62.40  ? 3   DA  B "O3'" 1 
ATOM   46   C "C2'" . DA  A 1 3  ? -0.093  0.735   16.606  1.00 60.09  ? 3   DA  B "C2'" 1 
ATOM   47   C "C1'" . DA  A 1 3  ? -0.480  1.857   17.563  1.00 61.14  ? 3   DA  B "C1'" 1 
ATOM   48   N N9    . DA  A 1 3  ? 0.628   2.642   18.080  1.00 62.91  ? 3   DA  B N9    1 
ATOM   49   C C8    . DA  A 1 3  ? 1.794   2.151   18.631  1.00 64.10  ? 3   DA  B C8    1 
ATOM   50   N N7    . DA  A 1 3  ? 2.611   3.094   19.042  1.00 59.50  ? 3   DA  B N7    1 
ATOM   51   C C5    . DA  A 1 3  ? 1.941   4.257   18.734  1.00 54.79  ? 3   DA  B C5    1 
ATOM   52   C C6    . DA  A 1 3  ? 2.286   5.590   18.938  1.00 59.37  ? 3   DA  B C6    1 
ATOM   53   N N6    . DA  A 1 3  ? 3.424   5.934   19.514  1.00 62.30  ? 3   DA  B N6    1 
ATOM   54   N N1    . DA  A 1 3  ? 1.382   6.540   18.575  1.00 67.42  ? 3   DA  B N1    1 
ATOM   55   C C2    . DA  A 1 3  ? 0.231   6.148   17.999  1.00 63.12  ? 3   DA  B C2    1 
ATOM   56   N N3    . DA  A 1 3  ? -0.191  4.912   17.741  1.00 64.39  ? 3   DA  B N3    1 
ATOM   57   C C4    . DA  A 1 3  ? 0.719   4.005   18.143  1.00 57.90  ? 3   DA  B C4    1 
ATOM   58   P P     . DA  A 1 4  ? -2.453  -0.112  14.602  1.00 65.73  ? 4   DA  B P     1 
ATOM   59   O OP1   . DA  A 1 4  ? -3.786  -0.484  14.038  1.00 59.54  ? 4   DA  B OP1   1 
ATOM   60   O OP2   . DA  A 1 4  ? -1.284  -0.955  14.218  1.00 74.59  ? 4   DA  B OP2   1 
ATOM   61   O "O5'" . DA  A 1 4  ? -2.145  1.406   14.199  1.00 63.10  ? 4   DA  B "O5'" 1 
ATOM   62   C "C5'" . DA  A 1 4  ? -3.143  2.373   14.560  1.00 65.18  ? 4   DA  B "C5'" 1 
ATOM   63   C "C4'" . DA  A 1 4  ? -2.818  3.731   14.002  1.00 64.03  ? 4   DA  B "C4'" 1 
ATOM   64   O "O4'" . DA  A 1 4  ? -1.655  4.236   14.681  1.00 57.97  ? 4   DA  B "O4'" 1 
ATOM   65   C "C3'" . DA  A 1 4  ? -2.546  3.782   12.495  1.00 60.86  ? 4   DA  B "C3'" 1 
ATOM   66   O "O3'" . DA  A 1 4  ? -3.359  4.850   12.024  1.00 60.53  ? 4   DA  B "O3'" 1 
ATOM   67   C "C2'" . DA  A 1 4  ? -1.036  4.008   12.425  1.00 58.41  ? 4   DA  B "C2'" 1 
ATOM   68   C "C1'" . DA  A 1 4  ? -0.795  4.801   13.700  1.00 62.28  ? 4   DA  B "C1'" 1 
ATOM   69   N N9    . DA  A 1 4  ? 0.538   4.702   14.268  1.00 62.91  ? 4   DA  B N9    1 
ATOM   70   C C8    . DA  A 1 4  ? 1.221   3.544   14.516  1.00 53.31  ? 4   DA  B C8    1 
ATOM   71   N N7    . DA  A 1 4  ? 2.367   3.747   15.108  1.00 53.84  ? 4   DA  B N7    1 
ATOM   72   C C5    . DA  A 1 4  ? 2.465   5.128   15.208  1.00 55.20  ? 4   DA  B C5    1 
ATOM   73   C C6    . DA  A 1 4  ? 3.450   5.954   15.762  1.00 57.45  ? 4   DA  B C6    1 
ATOM   74   N N6    . DA  A 1 4  ? 4.565   5.470   16.297  1.00 53.81  ? 4   DA  B N6    1 
ATOM   75   N N1    . DA  A 1 4  ? 3.208   7.292   15.787  1.00 65.80  ? 4   DA  B N1    1 
ATOM   76   C C2    . DA  A 1 4  ? 2.068   7.748   15.246  1.00 61.66  ? 4   DA  B C2    1 
ATOM   77   N N3    . DA  A 1 4  ? 1.067   7.058   14.704  1.00 61.24  ? 4   DA  B N3    1 
ATOM   78   C C4    . DA  A 1 4  ? 1.323   5.735   14.735  1.00 60.31  ? 4   DA  B C4    1 
ATOM   79   P P     . DA  A 1 5  ? -3.267  5.441   10.532  1.00 72.37  ? 5   DA  B P     1 
ATOM   80   O OP1   . DA  A 1 5  ? -4.615  5.898   10.096  1.00 75.28  ? 5   DA  B OP1   1 
ATOM   81   O OP2   . DA  A 1 5  ? -2.596  4.396   9.710   1.00 71.57  ? 5   DA  B OP2   1 
ATOM   82   O "O5'" . DA  A 1 5  ? -2.264  6.648   10.868  1.00 65.89  ? 5   DA  B "O5'" 1 
ATOM   83   C "C5'" . DA  A 1 5  ? -2.816  7.889   11.384  1.00 73.16  ? 5   DA  B "C5'" 1 
ATOM   84   C "C4'" . DA  A 1 5  ? -1.805  8.982   11.185  1.00 69.73  ? 5   DA  B "C4'" 1 
ATOM   85   O "O4'" . DA  A 1 5  ? -0.554  8.609   11.804  1.00 63.34  ? 5   DA  B "O4'" 1 
ATOM   86   C "C3'" . DA  A 1 5  ? -1.495  9.236   9.710   1.00 74.62  ? 5   DA  B "C3'" 1 
ATOM   87   O "O3'" . DA  A 1 5  ? -1.520  10.632  9.494   1.00 73.77  ? 5   DA  B "O3'" 1 
ATOM   88   C "C2'" . DA  A 1 5  ? -0.086  8.677   9.513   1.00 69.17  ? 5   DA  B "C2'" 1 
ATOM   89   C "C1'" . DA  A 1 5  ? 0.510   8.899   10.894  1.00 73.59  ? 5   DA  B "C1'" 1 
ATOM   90   N N9    . DA  A 1 5  ? 1.598   8.025   11.306  1.00 64.82  ? 5   DA  B N9    1 
ATOM   91   C C8    . DA  A 1 5  ? 1.640   6.651   11.336  1.00 64.03  ? 5   DA  B C8    1 
ATOM   92   N N7    . DA  A 1 5  ? 2.719   6.176   11.903  1.00 60.78  ? 5   DA  B N7    1 
ATOM   93   C C5    . DA  A 1 5  ? 3.388   7.312   12.330  1.00 53.61  ? 5   DA  B C5    1 
ATOM   94   C C6    . DA  A 1 5  ? 4.603   7.480   13.012  1.00 65.23  ? 5   DA  B C6    1 
ATOM   95   N N6    . DA  A 1 5  ? 5.345   6.450   13.394  1.00 65.64  ? 5   DA  B N6    1 
ATOM   96   N N1    . DA  A 1 5  ? 5.018   8.750   13.281  1.00 65.18  ? 5   DA  B N1    1 
ATOM   97   C C2    . DA  A 1 5  ? 4.231   9.764   12.872  1.00 74.35  ? 5   DA  B C2    1 
ATOM   98   N N3    . DA  A 1 5  ? 3.054   9.721   12.241  1.00 70.49  ? 5   DA  B N3    1 
ATOM   99   C C4    . DA  A 1 5  ? 2.700   8.455   11.982  1.00 56.38  ? 5   DA  B C4    1 
ATOM   100  P P     . DC  A 1 6  ? -1.685  11.189  8.005   1.00 87.10  ? 6   DC  B P     1 
ATOM   101  O OP1   . DC  A 1 6  ? -2.797  12.177  8.000   1.00 79.24  ? 6   DC  B OP1   1 
ATOM   102  O OP2   . DC  A 1 6  ? -1.760  10.031  7.063   1.00 74.70  ? 6   DC  B OP2   1 
ATOM   103  O "O5'" . DC  A 1 6  ? -0.271  11.937  7.867   1.00 89.44  ? 6   DC  B "O5'" 1 
ATOM   104  C "C5'" . DC  A 1 6  ? 0.209   12.833  8.915   1.00 88.98  ? 6   DC  B "C5'" 1 
ATOM   105  C "C4'" . DC  A 1 6  ? 1.700   13.034  8.759   1.00 89.26  ? 6   DC  B "C4'" 1 
ATOM   106  O "O4'" . DC  A 1 6  ? 2.415   11.979  9.435   1.00 84.79  ? 6   DC  B "O4'" 1 
ATOM   107  C "C3'" . DC  A 1 6  ? 2.213   13.012  7.316   1.00 92.81  ? 6   DC  B "C3'" 1 
ATOM   108  O "O3'" . DC  A 1 6  ? 2.497   14.304  6.802   1.00 97.57  ? 6   DC  B "O3'" 1 
ATOM   109  C "C2'" . DC  A 1 6  ? 3.549   12.286  7.375   1.00 90.37  ? 6   DC  B "C2'" 1 
ATOM   110  C "C1'" . DC  A 1 6  ? 3.680   11.823  8.819   1.00 87.52  ? 6   DC  B "C1'" 1 
ATOM   111  N N1    . DC  A 1 6  ? 4.064   10.400  8.942   1.00 70.87  ? 6   DC  B N1    1 
ATOM   112  C C2    . DC  A 1 6  ? 5.258   10.073  9.602   1.00 74.43  ? 6   DC  B C2    1 
ATOM   113  O O2    . DC  A 1 6  ? 5.950   10.998  10.068  1.00 65.02  ? 6   DC  B O2    1 
ATOM   114  N N3    . DC  A 1 6  ? 5.596   8.756   9.743   1.00 63.71  ? 6   DC  B N3    1 
ATOM   115  C C4    . DC  A 1 6  ? 4.814   7.808   9.202   1.00 66.81  ? 6   DC  B C4    1 
ATOM   116  N N4    . DC  A 1 6  ? 5.181   6.540   9.352   1.00 71.90  ? 6   DC  B N4    1 
ATOM   117  C C5    . DC  A 1 6  ? 3.623   8.133   8.481   1.00 64.52  ? 6   DC  B C5    1 
ATOM   118  C C6    . DC  A 1 6  ? 3.282   9.431   8.390   1.00 64.89  ? 6   DC  B C6    1 
ATOM   119  P P     . DG  A 1 7  ? 2.661   14.542  5.217   1.00 93.13  ? 7   DG  B P     1 
ATOM   120  O OP1   . DG  A 1 7  ? 1.919   15.813  4.963   1.00 96.14  ? 7   DG  B OP1   1 
ATOM   121  O OP2   . DG  A 1 7  ? 2.324   13.327  4.421   1.00 98.71  ? 7   DG  B OP2   1 
ATOM   122  O "O5'" . DG  A 1 7  ? 4.248   14.726  5.129   1.00 88.40  ? 7   DG  B "O5'" 1 
ATOM   123  C "C5'" . DG  A 1 7  ? 4.873   15.678  6.037   1.00 91.89  ? 7   DG  B "C5'" 1 
ATOM   124  C "C4'" . DG  A 1 7  ? 6.373   15.560  5.920   1.00 85.84  ? 7   DG  B "C4'" 1 
ATOM   125  O "O4'" . DG  A 1 7  ? 6.805   14.341  6.561   1.00 78.12  ? 7   DG  B "O4'" 1 
ATOM   126  C "C3'" . DG  A 1 7  ? 6.916   15.528  4.490   1.00 79.92  ? 7   DG  B "C3'" 1 
ATOM   127  O "O3'" . DG  A 1 7  ? 8.120   16.266  4.453   1.00 77.52  ? 7   DG  B "O3'" 1 
ATOM   128  C "C2'" . DG  A 1 7  ? 7.189   14.050  4.247   1.00 77.63  ? 7   DG  B "C2'" 1 
ATOM   129  C "C1'" . DG  A 1 7  ? 7.533   13.544  5.641   1.00 79.76  ? 7   DG  B "C1'" 1 
ATOM   130  N N9    . DG  A 1 7  ? 7.188   12.140  5.841   1.00 73.86  ? 7   DG  B N9    1 
ATOM   131  C C8    . DG  A 1 7  ? 6.128   11.471  5.281   1.00 72.26  ? 7   DG  B C8    1 
ATOM   132  N N7    . DG  A 1 7  ? 6.096   10.194  5.580   1.00 67.64  ? 7   DG  B N7    1 
ATOM   133  C C5    . DG  A 1 7  ? 7.215   10.020  6.381   1.00 69.28  ? 7   DG  B C5    1 
ATOM   134  C C6    . DG  A 1 7  ? 7.705   8.840   6.974   1.00 61.35  ? 7   DG  B C6    1 
ATOM   135  O O6    . DG  A 1 7  ? 7.184   7.720   6.936   1.00 66.95  ? 7   DG  B O6    1 
ATOM   136  N N1    . DG  A 1 7  ? 8.887   9.073   7.681   1.00 62.23  ? 7   DG  B N1    1 
ATOM   137  C C2    . DG  A 1 7  ? 9.504   10.296  7.804   1.00 67.12  ? 7   DG  B C2    1 
ATOM   138  N N2    . DG  A 1 7  ? 10.652  10.322  8.491   1.00 68.19  ? 7   DG  B N2    1 
ATOM   139  N N3    . DG  A 1 7  ? 9.043   11.416  7.244   1.00 72.84  ? 7   DG  B N3    1 
ATOM   140  C C4    . DG  A 1 7  ? 7.907   11.201  6.539   1.00 70.71  ? 7   DG  B C4    1 
ATOM   141  P P     . DG  A 1 8  ? 8.987   16.494  3.119   1.00 77.68  ? 8   DG  B P     1 
ATOM   142  O OP1   . DG  A 1 8  ? 9.220   17.934  3.410   1.00 84.92  ? 8   DG  B OP1   1 
ATOM   143  O OP2   . DG  A 1 8  ? 8.426   16.033  1.811   1.00 82.44  ? 8   DG  B OP2   1 
ATOM   144  O "O5'" . DG  A 1 8  ? 10.230  15.543  3.429   1.00 65.00  ? 8   DG  B "O5'" 1 
ATOM   145  C "C5'" . DG  A 1 8  ? 11.021  15.860  4.594   1.00 72.96  ? 8   DG  B "C5'" 1 
ATOM   146  C "C4'" . DG  A 1 8  ? 12.155  14.873  4.665   1.00 77.52  ? 8   DG  B "C4'" 1 
ATOM   147  O "O4'" . DG  A 1 8  ? 11.621  13.612  5.120   1.00 76.56  ? 8   DG  B "O4'" 1 
ATOM   148  C "C3'" . DG  A 1 8  ? 12.836  14.619  3.311   1.00 84.17  ? 8   DG  B "C3'" 1 
ATOM   149  O "O3'" . DG  A 1 8  ? 14.239  14.524  3.472   1.00 78.27  ? 8   DG  B "O3'" 1 
ATOM   150  C "C2'" . DG  A 1 8  ? 12.245  13.285  2.869   1.00 81.21  ? 8   DG  B "C2'" 1 
ATOM   151  C "C1'" . DG  A 1 8  ? 12.004  12.593  4.206   1.00 75.50  ? 8   DG  B "C1'" 1 
ATOM   152  N N9    . DG  A 1 8  ? 10.971  11.569  4.116   1.00 75.53  ? 8   DG  B N9    1 
ATOM   153  C C8    . DG  A 1 8  ? 9.754   11.643  3.472   1.00 78.97  ? 8   DG  B C8    1 
ATOM   154  N N7    . DG  A 1 8  ? 9.084   10.513  3.474   1.00 68.66  ? 8   DG  B N7    1 
ATOM   155  C C5    . DG  A 1 8  ? 9.932   9.649   4.155   1.00 65.56  ? 8   DG  B C5    1 
ATOM   156  C C6    . DG  A 1 8  ? 9.737   8.299   4.463   1.00 68.42  ? 8   DG  B C6    1 
ATOM   157  O O6    . DG  A 1 8  ? 8.752   7.617   4.162   1.00 76.21  ? 8   DG  B O6    1 
ATOM   158  N N1    . DG  A 1 8  ? 10.839  7.760   5.146   1.00 75.62  ? 8   DG  B N1    1 
ATOM   159  C C2    . DG  A 1 8  ? 11.987  8.447   5.488   1.00 73.42  ? 8   DG  B C2    1 
ATOM   160  N N2    . DG  A 1 8  ? 12.926  7.760   6.169   1.00 66.42  ? 8   DG  B N2    1 
ATOM   161  N N3    . DG  A 1 8  ? 12.171  9.741   5.197   1.00 66.75  ? 8   DG  B N3    1 
ATOM   162  C C4    . DG  A 1 8  ? 11.105  10.267  4.539   1.00 71.82  ? 8   DG  B C4    1 
ATOM   163  P P     . DG  A 1 9  ? 15.218  14.485  2.206   1.00 75.26  ? 9   DG  B P     1 
ATOM   164  O OP1   . DG  A 1 9  ? 16.291  15.434  2.615   1.00 76.84  ? 9   DG  B OP1   1 
ATOM   165  O OP2   . DG  A 1 9  ? 14.545  14.599  0.873   1.00 60.06  ? 9   DG  B OP2   1 
ATOM   166  O "O5'" . DG  A 1 9  ? 15.745  12.994  2.460   1.00 71.33  ? 9   DG  B "O5'" 1 
ATOM   167  C "C5'" . DG  A 1 9  ? 16.645  12.756  3.589   1.00 69.49  ? 9   DG  B "C5'" 1 
ATOM   168  C "C4'" . DG  A 1 9  ? 16.907  11.270  3.703   1.00 67.78  ? 9   DG  B "C4'" 1 
ATOM   169  O "O4'" . DG  A 1 9  ? 15.632  10.606  3.746   1.00 69.38  ? 9   DG  B "O4'" 1 
ATOM   170  C "C3'" . DG  A 1 9  ? 17.677  10.633  2.548   1.00 65.67  ? 9   DG  B "C3'" 1 
ATOM   171  O "O3'" . DG  A 1 9  ? 18.916  10.084  2.950   1.00 66.16  ? 9   DG  B "O3'" 1 
ATOM   172  C "C2'" . DG  A 1 9  ? 16.799  9.500   2.028   1.00 66.78  ? 9   DG  B "C2'" 1 
ATOM   173  C "C1'" . DG  A 1 9  ? 15.738  9.349   3.085   1.00 67.43  ? 9   DG  B "C1'" 1 
ATOM   174  N N9    . DG  A 1 9  ? 14.428  9.090   2.529   1.00 63.51  ? 9   DG  B N9    1 
ATOM   175  C C8    . DG  A 1 9  ? 13.610  10.011  1.922   1.00 67.99  ? 9   DG  B C8    1 
ATOM   176  N N7    . DG  A 1 9  ? 12.464  9.513   1.529   1.00 68.50  ? 9   DG  B N7    1 
ATOM   177  C C5    . DG  A 1 9  ? 12.526  8.196   1.963   1.00 69.21  ? 9   DG  B C5    1 
ATOM   178  C C6    . DG  A 1 9  ? 11.562  7.184   1.833   1.00 68.19  ? 9   DG  B C6    1 
ATOM   179  O O6    . DG  A 1 9  ? 10.453  7.290   1.284   1.00 67.79  ? 9   DG  B O6    1 
ATOM   180  N N1    . DG  A 1 9  ? 12.012  5.988   2.421   1.00 65.12  ? 9   DG  B N1    1 
ATOM   181  C C2    . DG  A 1 9  ? 13.247  5.791   3.003   1.00 65.95  ? 9   DG  B C2    1 
ATOM   182  N N2    . DG  A 1 9  ? 13.531  4.538   3.405   1.00 60.07  ? 9   DG  B N2    1 
ATOM   183  N N3    . DG  A 1 9  ? 14.175  6.751   3.114   1.00 58.22  ? 9   DG  B N3    1 
ATOM   184  C C4    . DG  A 1 9  ? 13.738  7.911   2.566   1.00 67.89  ? 9   DG  B C4    1 
ATOM   185  P P     . DC  A 1 10 ? 19.949  9.550   1.839   1.00 68.97  ? 10  DC  B P     1 
ATOM   186  O OP1   . DC  A 1 10 ? 21.252  9.667   2.552   1.00 73.88  ? 10  DC  B OP1   1 
ATOM   187  O OP2   . DC  A 1 10 ? 19.770  10.182  0.493   1.00 61.65  ? 10  DC  B OP2   1 
ATOM   188  O "O5'" . DC  A 1 10 ? 19.516  8.013   1.684   1.00 76.11  ? 10  DC  B "O5'" 1 
ATOM   189  C "C5'" . DC  A 1 10 ? 19.398  7.184   2.894   1.00 74.21  ? 10  DC  B "C5'" 1 
ATOM   190  C "C4'" . DC  A 1 10 ? 19.085  5.765   2.496   1.00 71.93  ? 10  DC  B "C4'" 1 
ATOM   191  O "O4'" . DC  A 1 10 ? 17.681  5.621   2.173   1.00 69.13  ? 10  DC  B "O4'" 1 
ATOM   192  C "C3'" . DC  A 1 10 ? 19.849  5.294   1.259   1.00 80.74  ? 10  DC  B "C3'" 1 
ATOM   193  O "O3'" . DC  A 1 10 ? 20.366  4.011   1.522   1.00 71.90  ? 10  DC  B "O3'" 1 
ATOM   194  C "C2'" . DC  A 1 10 ? 18.798  5.190   0.158   1.00 77.27  ? 10  DC  B "C2'" 1 
ATOM   195  C "C1'" . DC  A 1 10 ? 17.540  4.898   0.958   1.00 71.20  ? 10  DC  B "C1'" 1 
ATOM   196  N N1    . DC  A 1 10 ? 16.267  5.337   0.337   1.00 68.01  ? 10  DC  B N1    1 
ATOM   197  C C2    . DC  A 1 10 ? 15.204  4.438   0.244   1.00 61.18  ? 10  DC  B C2    1 
ATOM   198  O O2    . DC  A 1 10 ? 15.354  3.270   0.629   1.00 62.70  ? 10  DC  B O2    1 
ATOM   199  N N3    . DC  A 1 10 ? 14.052  4.852   -0.309  1.00 62.68  ? 10  DC  B N3    1 
ATOM   200  C C4    . DC  A 1 10 ? 13.906  6.121   -0.709  1.00 60.72  ? 10  DC  B C4    1 
ATOM   201  N N4    . DC  A 1 10 ? 12.730  6.486   -1.190  1.00 64.29  ? 10  DC  B N4    1 
ATOM   202  C C5    . DC  A 1 10 ? 14.961  7.052   -0.611  1.00 61.85  ? 10  DC  B C5    1 
ATOM   203  C C6    . DC  A 1 10 ? 16.125  6.615   -0.107  1.00 68.04  ? 10  DC  B C6    1 
ATOM   204  P P     . DA  A 1 11 ? 21.687  3.523   0.785   1.00 80.39  ? 11  DA  B P     1 
ATOM   205  O OP1   . DA  A 1 11 ? 22.475  2.889   1.885   1.00 80.39  ? 11  DA  B OP1   1 
ATOM   206  O OP2   . DA  A 1 11 ? 22.273  4.624   -0.030  1.00 85.63  ? 11  DA  B OP2   1 
ATOM   207  O "O5'" . DA  A 1 11 ? 21.067  2.437   -0.216  1.00 84.55  ? 11  DA  B "O5'" 1 
ATOM   208  C "C5'" . DA  A 1 11 ? 20.518  1.226   0.370   1.00 86.46  ? 11  DA  B "C5'" 1 
ATOM   209  C "C4'" . DA  A 1 11 ? 19.507  0.606   -0.566  1.00 83.20  ? 11  DA  B "C4'" 1 
ATOM   210  O "O4'" . DA  A 1 11 ? 18.462  1.547   -0.871  1.00 75.00  ? 11  DA  B "O4'" 1 
ATOM   211  C "C3'" . DA  A 1 11 ? 20.081  0.158   -1.909  1.00 76.19  ? 11  DA  B "C3'" 1 
ATOM   212  O "O3'" . DA  A 1 11 ? 19.914  -1.241  -2.053  1.00 77.94  ? 11  DA  B "O3'" 1 
ATOM   213  C "C2'" . DA  A 1 11 ? 19.269  0.906   -2.963  1.00 70.45  ? 11  DA  B "C2'" 1 
ATOM   214  C "C1'" . DA  A 1 11 ? 18.019  1.288   -2.201  1.00 69.61  ? 11  DA  B "C1'" 1 
ATOM   215  N N9    . DA  A 1 11 ? 17.324  2.489   -2.650  1.00 66.59  ? 11  DA  B N9    1 
ATOM   216  C C8    . DA  A 1 11 ? 17.791  3.773   -2.831  1.00 59.20  ? 11  DA  B C8    1 
ATOM   217  N N7    . DA  A 1 11 ? 16.852  4.617   -3.199  1.00 61.62  ? 11  DA  B N7    1 
ATOM   218  C C5    . DA  A 1 11 ? 15.699  3.842   -3.247  1.00 56.74  ? 11  DA  B C5    1 
ATOM   219  C C6    . DA  A 1 11 ? 14.370  4.143   -3.572  1.00 59.47  ? 11  DA  B C6    1 
ATOM   220  N N6    . DA  A 1 11 ? 13.953  5.369   -3.868  1.00 63.05  ? 11  DA  B N6    1 
ATOM   221  N N1    . DA  A 1 11 ? 13.467  3.122   -3.546  1.00 69.98  ? 11  DA  B N1    1 
ATOM   222  C C2    . DA  A 1 11 ? 13.882  1.888   -3.211  1.00 60.85  ? 11  DA  B C2    1 
ATOM   223  N N3    . DA  A 1 11 ? 15.107  1.487   -2.898  1.00 63.41  ? 11  DA  B N3    1 
ATOM   224  C C4    . DA  A 1 11 ? 15.974  2.522   -2.923  1.00 67.55  ? 11  DA  B C4    1 
ATOM   225  P P     . DA  A 1 12 ? 20.585  -1.971  -3.312  1.00 82.37  ? 12  DA  B P     1 
ATOM   226  O OP1   . DA  A 1 12 ? 21.250  -3.231  -2.851  1.00 81.27  ? 12  DA  B OP1   1 
ATOM   227  O OP2   . DA  A 1 12 ? 21.376  -0.905  -3.988  1.00 68.68  ? 12  DA  B OP2   1 
ATOM   228  O "O5'" . DA  A 1 12 ? 19.282  -2.179  -4.204  1.00 74.59  ? 12  DA  B "O5'" 1 
ATOM   229  C "C5'" . DA  A 1 12 ? 18.062  -2.655  -3.577  1.00 78.38  ? 12  DA  B "C5'" 1 
ATOM   230  C "C4'" . DA  A 1 12 ? 16.957  -2.619  -4.604  1.00 82.28  ? 12  DA  B "C4'" 1 
ATOM   231  O "O4'" . DA  A 1 12 ? 16.398  -1.291  -4.685  1.00 81.26  ? 12  DA  B "O4'" 1 
ATOM   232  C "C3'" . DA  A 1 12 ? 17.413  -2.956  -6.021  1.00 84.06  ? 12  DA  B "C3'" 1 
ATOM   233  O "O3'" . DA  A 1 12 ? 16.409  -3.760  -6.595  1.00 91.56  ? 12  DA  B "O3'" 1 
ATOM   234  C "C2'" . DA  A 1 12 ? 17.494  -1.605  -6.729  1.00 77.69  ? 12  DA  B "C2'" 1 
ATOM   235  C "C1'" . DA  A 1 12 ? 16.340  -0.893  -6.053  1.00 75.82  ? 12  DA  B "C1'" 1 
ATOM   236  N N9    . DA  A 1 12 ? 16.398  0.558   -6.127  1.00 66.13  ? 12  DA  B N9    1 
ATOM   237  C C8    . DA  A 1 12 ? 17.466  1.404   -5.960  1.00 64.32  ? 12  DA  B C8    1 
ATOM   238  N N7    . DA  A 1 12 ? 17.153  2.666   -6.117  1.00 66.82  ? 12  DA  B N7    1 
ATOM   239  C C5    . DA  A 1 12 ? 15.795  2.646   -6.410  1.00 57.86  ? 12  DA  B C5    1 
ATOM   240  C C6    . DA  A 1 12 ? 14.871  3.677   -6.667  1.00 65.15  ? 12  DA  B C6    1 
ATOM   241  N N6    . DA  A 1 12 ? 15.210  4.961   -6.665  1.00 64.80  ? 12  DA  B N6    1 
ATOM   242  N N1    . DA  A 1 12 ? 13.574  3.332   -6.905  1.00 71.46  ? 12  DA  B N1    1 
ATOM   243  C C2    . DA  A 1 12 ? 13.260  2.022   -6.860  1.00 79.77  ? 12  DA  B C2    1 
ATOM   244  N N3    . DA  A 1 12 ? 14.049  0.963   -6.632  1.00 64.26  ? 12  DA  B N3    1 
ATOM   245  C C4    . DA  A 1 12 ? 15.313  1.352   -6.398  1.00 59.86  ? 12  DA  B C4    1 
ATOM   246  P P     . DT  A 1 13 ? 16.638  -4.371  -8.060  1.00 92.41  ? 13  DT  B P     1 
ATOM   247  O OP1   . DT  A 1 13 ? 16.360  -5.799  -7.706  1.00 92.59  ? 13  DT  B OP1   1 
ATOM   248  O OP2   . DT  A 1 13 ? 17.904  -3.980  -8.750  1.00 83.67  ? 13  DT  B OP2   1 
ATOM   249  O "O5'" . DT  A 1 13 ? 15.482  -3.583  -8.818  1.00 82.98  ? 13  DT  B "O5'" 1 
ATOM   250  C "C5'" . DT  A 1 13 ? 14.145  -3.626  -8.264  1.00 77.65  ? 13  DT  B "C5'" 1 
ATOM   251  C "C4'" . DT  A 1 13 ? 13.360  -2.618  -9.051  1.00 78.14  ? 13  DT  B "C4'" 1 
ATOM   252  O "O4'" . DT  A 1 13 ? 13.901  -1.298  -8.822  1.00 66.05  ? 13  DT  B "O4'" 1 
ATOM   253  C "C3'" . DT  A 1 13 ? 13.418  -2.838  -10.566 1.00 74.63  ? 13  DT  B "C3'" 1 
ATOM   254  O "O3'" . DT  A 1 13 ? 12.068  -3.054  -10.924 1.00 77.08  ? 13  DT  B "O3'" 1 
ATOM   255  C "C2'" . DT  A 1 13 ? 13.953  -1.525  -11.119 1.00 74.88  ? 13  DT  B "C2'" 1 
ATOM   256  C "C1'" . DT  A 1 13 ? 13.654  -0.546  -9.983  1.00 67.06  ? 13  DT  B "C1'" 1 
ATOM   257  N N1    . DT  A 1 13 ? 14.519  0.646   -9.915  1.00 64.81  ? 13  DT  B N1    1 
ATOM   258  C C2    . DT  A 1 13 ? 13.929  1.873   -10.081 1.00 62.11  ? 13  DT  B C2    1 
ATOM   259  O O2    . DT  A 1 13 ? 12.731  1.979   -10.264 1.00 61.74  ? 13  DT  B O2    1 
ATOM   260  N N3    . DT  A 1 13 ? 14.788  2.951   -10.054 1.00 62.15  ? 13  DT  B N3    1 
ATOM   261  C C4    . DT  A 1 13 ? 16.149  2.906   -9.827  1.00 60.50  ? 13  DT  B C4    1 
ATOM   262  O O4    . DT  A 1 13 ? 16.793  3.931   -9.818  1.00 64.78  ? 13  DT  B O4    1 
ATOM   263  C C5    . DT  A 1 13 ? 16.717  1.589   -9.680  1.00 64.30  ? 13  DT  B C5    1 
ATOM   264  C C7    . DT  A 1 13 ? 18.200  1.460   -9.482  1.00 65.73  ? 13  DT  B C7    1 
ATOM   265  C C6    . DT  A 1 13 ? 15.883  0.531   -9.735  1.00 66.70  ? 13  DT  B C6    1 
ATOM   266  P P     . DT  A 1 14 ? 11.663  -3.521  -12.390 1.00 77.92  ? 14  DT  B P     1 
ATOM   267  O OP1   . DT  A 1 14 ? 10.503  -4.430  -12.148 1.00 84.33  ? 14  DT  B OP1   1 
ATOM   268  O OP2   . DT  A 1 14 ? 12.934  -4.043  -12.944 1.00 77.51  ? 14  DT  B OP2   1 
ATOM   269  O "O5'" . DT  A 1 14 ? 11.187  -2.168  -13.075 1.00 70.67  ? 14  DT  B "O5'" 1 
ATOM   270  C "C5'" . DT  A 1 14 ? 10.137  -1.467  -12.409 1.00 74.55  ? 14  DT  B "C5'" 1 
ATOM   271  C "C4'" . DT  A 1 14 ? 9.869   -0.215  -13.189 1.00 72.92  ? 14  DT  B "C4'" 1 
ATOM   272  O "O4'" . DT  A 1 14 ? 10.877  0.767   -12.886 1.00 63.97  ? 14  DT  B "O4'" 1 
ATOM   273  C "C3'" . DT  A 1 14 ? 9.886   -0.417  -14.697 1.00 73.27  ? 14  DT  B "C3'" 1 
ATOM   274  O "O3'" . DT  A 1 14 ? 8.614   0.060   -15.079 1.00 81.31  ? 14  DT  B "O3'" 1 
ATOM   275  C "C2'" . DT  A 1 14 ? 11.041  0.440   -15.196 1.00 67.75  ? 14  DT  B "C2'" 1 
ATOM   276  C "C1'" . DT  A 1 14 ? 11.198  1.471   -14.078 1.00 66.73  ? 14  DT  B "C1'" 1 
ATOM   277  N N1    . DT  A 1 14 ? 12.562  2.000   -13.891 1.00 56.33  ? 14  DT  B N1    1 
ATOM   278  C C2    . DT  A 1 14 ? 12.760  3.362   -13.833 1.00 56.97  ? 14  DT  B C2    1 
ATOM   279  O O2    . DT  A 1 14 ? 11.860  4.170   -13.986 1.00 64.02  ? 14  DT  B O2    1 
ATOM   280  N N3    . DT  A 1 14 ? 14.063  3.753   -13.628 1.00 58.25  ? 14  DT  B N3    1 
ATOM   281  C C4    . DT  A 1 14 ? 15.160  2.930   -13.465 1.00 58.48  ? 14  DT  B C4    1 
ATOM   282  O O4    . DT  A 1 14 ? 16.255  3.434   -13.272 1.00 59.32  ? 14  DT  B O4    1 
ATOM   283  C C5    . DT  A 1 14 ? 14.876  1.508   -13.497 1.00 65.75  ? 14  DT  B C5    1 
ATOM   284  C C7    . DT  A 1 14 ? 15.993  0.516   -13.338 1.00 67.84  ? 14  DT  B C7    1 
ATOM   285  C C6    . DT  A 1 14 ? 13.606  1.123   -13.696 1.00 63.60  ? 14  DT  B C6    1 
ATOM   286  P P     . DA  A 1 15 ? 8.146   -0.015  -16.602 1.00 78.42  ? 15  DA  B P     1 
ATOM   287  O OP1   . DA  A 1 15 ? 6.681   0.215   -16.730 1.00 74.23  ? 15  DA  B OP1   1 
ATOM   288  O OP2   . DA  A 1 15 ? 8.781   -1.191  -17.262 1.00 86.45  ? 15  DA  B OP2   1 
ATOM   289  O "O5'" . DA  A 1 15 ? 8.817   1.326   -17.129 1.00 76.75  ? 15  DA  B "O5'" 1 
ATOM   290  C "C5'" . DA  A 1 15 ? 8.043   2.534   -17.059 1.00 73.33  ? 15  DA  B "C5'" 1 
ATOM   291  C "C4'" . DA  A 1 15 ? 8.914   3.636   -17.582 1.00 71.96  ? 15  DA  B "C4'" 1 
ATOM   292  O "O4'" . DA  A 1 15 ? 10.209  3.526   -16.941 1.00 67.13  ? 15  DA  B "O4'" 1 
ATOM   293  C "C3'" . DA  A 1 15 ? 9.150   3.510   -19.091 1.00 71.74  ? 15  DA  B "C3'" 1 
ATOM   294  O "O3'" . DA  A 1 15 ? 9.139   4.746   -19.781 1.00 73.78  ? 15  DA  B "O3'" 1 
ATOM   295  C "C2'" . DA  A 1 15 ? 10.561  2.944   -19.128 1.00 70.83  ? 15  DA  B "C2'" 1 
ATOM   296  C "C1'" . DA  A 1 15 ? 11.152  3.738   -17.985 1.00 70.04  ? 15  DA  B "C1'" 1 
ATOM   297  N N9    . DA  A 1 15 ? 12.461  3.303   -17.542 1.00 64.00  ? 15  DA  B N9    1 
ATOM   298  C C8    . DA  A 1 15 ? 12.941  2.028   -17.408 1.00 64.31  ? 15  DA  B C8    1 
ATOM   299  N N7    . DA  A 1 15 ? 14.177  1.997   -16.990 1.00 64.27  ? 15  DA  B N7    1 
ATOM   300  C C5    . DA  A 1 15 ? 14.525  3.331   -16.839 1.00 59.01  ? 15  DA  B C5    1 
ATOM   301  C C6    . DA  A 1 15 ? 15.714  3.959   -16.446 1.00 61.37  ? 15  DA  B C6    1 
ATOM   302  N N6    . DA  A 1 15 ? 16.794  3.291   -16.060 1.00 61.12  ? 15  DA  B N6    1 
ATOM   303  N N1    . DA  A 1 15 ? 15.747  5.316   -16.460 1.00 59.19  ? 15  DA  B N1    1 
ATOM   304  C C2    . DA  A 1 15 ? 14.640  5.976   -16.804 1.00 57.32  ? 15  DA  B C2    1 
ATOM   305  N N3    . DA  A 1 15 ? 13.466  5.490   -17.191 1.00 61.31  ? 15  DA  B N3    1 
ATOM   306  C C4    . DA  A 1 15 ? 13.476  4.148   -17.186 1.00 58.56  ? 15  DA  B C4    1 
ATOM   307  P P     . DG  A 1 16 ? 7.799   5.271   -20.489 1.00 78.59  ? 16  DG  B P     1 
ATOM   308  O OP1   . DG  A 1 16 ? 6.721   5.437   -19.471 1.00 83.24  ? 16  DG  B OP1   1 
ATOM   309  O OP2   . DG  A 1 16 ? 7.454   4.568   -21.756 1.00 81.93  ? 16  DG  B OP2   1 
ATOM   310  O "O5'" . DG  A 1 16 ? 8.521   6.651   -20.835 1.00 75.64  ? 16  DG  B "O5'" 1 
ATOM   311  C "C5'" . DG  A 1 16 ? 8.898   7.530   -19.738 1.00 72.45  ? 16  DG  B "C5'" 1 
ATOM   312  C "C4'" . DG  A 1 16 ? 9.494   8.826   -20.254 1.00 69.67  ? 16  DG  B "C4'" 1 
ATOM   313  O "O4'" . DG  A 1 16 ? 10.923  8.799   -20.074 1.00 78.62  ? 16  DG  B "O4'" 1 
ATOM   314  C "C3'" . DG  A 1 16 ? 9.308   9.161   -21.729 1.00 67.87  ? 16  DG  B "C3'" 1 
ATOM   315  O "O3'" . DG  A 1 16 ? 9.449   10.564  -21.890 1.00 66.79  ? 16  DG  B "O3'" 1 
ATOM   316  C "C2'" . DG  A 1 16 ? 10.481  8.440   -22.390 1.00 69.29  ? 16  DG  B "C2'" 1 
ATOM   317  C "C1'" . DG  A 1 16 ? 11.572  8.566   -21.333 1.00 73.41  ? 16  DG  B "C1'" 1 
ATOM   318  N N9    . DG  A 1 16 ? 12.385  7.365   -21.132 1.00 67.61  ? 16  DG  B N9    1 
ATOM   319  C C8    . DG  A 1 16 ? 11.991  6.044   -21.173 1.00 71.87  ? 16  DG  B C8    1 
ATOM   320  N N7    . DG  A 1 16 ? 12.956  5.204   -20.890 1.00 64.70  ? 16  DG  B N7    1 
ATOM   321  C C5    . DG  A 1 16 ? 14.033  6.035   -20.602 1.00 63.18  ? 16  DG  B C5    1 
ATOM   322  C C6    . DG  A 1 16 ? 15.355  5.697   -20.244 1.00 61.18  ? 16  DG  B C6    1 
ATOM   323  O O6    . DG  A 1 16 ? 15.819  4.568   -20.040 1.00 73.93  ? 16  DG  B O6    1 
ATOM   324  N N1    . DG  A 1 16 ? 16.150  6.832   -20.096 1.00 60.90  ? 16  DG  B N1    1 
ATOM   325  C C2    . DG  A 1 16 ? 15.727  8.129   -20.238 1.00 58.00  ? 16  DG  B C2    1 
ATOM   326  N N2    . DG  A 1 16 ? 16.640  9.084   -19.975 1.00 54.33  ? 16  DG  B N2    1 
ATOM   327  N N3    . DG  A 1 16 ? 14.465  8.452   -20.530 1.00 54.80  ? 16  DG  B N3    1 
ATOM   328  C C4    . DG  A 1 16 ? 13.697  7.362   -20.741 1.00 56.48  ? 16  DG  B C4    1 
ATOM   329  O "O5'" . DC  B 2 1  ? 24.640  7.074   -17.991 1.00 115.79 ? 1   DC  D "O5'" 1 
ATOM   330  C "C5'" . DC  B 2 1  ? 25.122  8.446   -17.910 1.00 91.49  ? 1   DC  D "C5'" 1 
ATOM   331  C "C4'" . DC  B 2 1  ? 23.996  9.427   -18.168 1.00 77.23  ? 1   DC  D "C4'" 1 
ATOM   332  O "O4'" . DC  B 2 1  ? 22.870  8.828   -18.859 1.00 72.60  ? 1   DC  D "O4'" 1 
ATOM   333  C "C3'" . DC  B 2 1  ? 23.420  10.016  -16.892 1.00 66.78  ? 1   DC  D "C3'" 1 
ATOM   334  O "O3'" . DC  B 2 1  ? 23.094  11.378  -17.086 1.00 65.46  ? 1   DC  D "O3'" 1 
ATOM   335  C "C2'" . DC  B 2 1  ? 22.160  9.191   -16.683 1.00 71.74  ? 1   DC  D "C2'" 1 
ATOM   336  C "C1'" . DC  B 2 1  ? 21.683  9.010   -18.110 1.00 67.10  ? 1   DC  D "C1'" 1 
ATOM   337  N N1    . DC  B 2 1  ? 20.831  7.821   -18.293 1.00 60.94  ? 1   DC  D N1    1 
ATOM   338  C C2    . DC  B 2 1  ? 19.493  7.940   -18.706 1.00 56.05  ? 1   DC  D C2    1 
ATOM   339  O O2    . DC  B 2 1  ? 19.021  9.043   -19.016 1.00 59.96  ? 1   DC  D O2    1 
ATOM   340  N N3    . DC  B 2 1  ? 18.754  6.823   -18.849 1.00 56.59  ? 1   DC  D N3    1 
ATOM   341  C C4    . DC  B 2 1  ? 19.289  5.623   -18.590 1.00 62.63  ? 1   DC  D C4    1 
ATOM   342  N N4    . DC  B 2 1  ? 18.548  4.552   -18.819 1.00 62.53  ? 1   DC  D N4    1 
ATOM   343  C C5    . DC  B 2 1  ? 20.634  5.485   -18.158 1.00 64.96  ? 1   DC  D C5    1 
ATOM   344  C C6    . DC  B 2 1  ? 21.354  6.604   -18.000 1.00 63.55  ? 1   DC  D C6    1 
ATOM   345  P P     . DT  B 2 2  ? 23.076  12.351  -15.814 1.00 63.52  ? 2   DT  D P     1 
ATOM   346  O OP1   . DT  B 2 2  ? 23.320  13.771  -16.213 1.00 59.89  ? 2   DT  D OP1   1 
ATOM   347  O OP2   . DT  B 2 2  ? 23.915  11.764  -14.741 1.00 68.91  ? 2   DT  D OP2   1 
ATOM   348  O "O5'" . DT  B 2 2  ? 21.569  12.072  -15.360 1.00 69.34  ? 2   DT  D "O5'" 1 
ATOM   349  C "C5'" . DT  B 2 2  ? 20.538  12.609  -16.238 1.00 66.55  ? 2   DT  D "C5'" 1 
ATOM   350  C "C4'" . DT  B 2 2  ? 19.186  12.119  -15.802 1.00 61.93  ? 2   DT  D "C4'" 1 
ATOM   351  O "O4'" . DT  B 2 2  ? 19.070  10.703  -16.081 1.00 63.52  ? 2   DT  D "O4'" 1 
ATOM   352  C "C3'" . DT  B 2 2  ? 18.901  12.304  -14.307 1.00 56.90  ? 2   DT  D "C3'" 1 
ATOM   353  O "O3'" . DT  B 2 2  ? 17.587  12.810  -14.170 1.00 58.47  ? 2   DT  D "O3'" 1 
ATOM   354  C "C2'" . DT  B 2 2  ? 18.987  10.885  -13.767 1.00 60.69  ? 2   DT  D "C2'" 1 
ATOM   355  C "C1'" . DT  B 2 2  ? 18.448  10.107  -14.958 1.00 62.07  ? 2   DT  D "C1'" 1 
ATOM   356  N N1    . DT  B 2 2  ? 18.738  8.665   -15.013 1.00 59.39  ? 2   DT  D N1    1 
ATOM   357  C C2    . DT  B 2 2  ? 17.774  7.912   -15.608 1.00 54.74  ? 2   DT  D C2    1 
ATOM   358  O O2    . DT  B 2 2  ? 16.761  8.412   -16.085 1.00 59.78  ? 2   DT  D O2    1 
ATOM   359  N N3    . DT  B 2 2  ? 18.017  6.575   -15.609 1.00 55.32  ? 2   DT  D N3    1 
ATOM   360  C C4    . DT  B 2 2  ? 19.108  5.920   -15.098 1.00 61.10  ? 2   DT  D C4    1 
ATOM   361  O O4    . DT  B 2 2  ? 19.189  4.699   -15.248 1.00 61.91  ? 2   DT  D O4    1 
ATOM   362  C C5    . DT  B 2 2  ? 20.101  6.777   -14.494 1.00 63.64  ? 2   DT  D C5    1 
ATOM   363  C C7    . DT  B 2 2  ? 21.338  6.157   -13.911 1.00 64.48  ? 2   DT  D C7    1 
ATOM   364  C C6    . DT  B 2 2  ? 19.871  8.096   -14.480 1.00 59.87  ? 2   DT  D C6    1 
ATOM   365  P P     . DA  B 2 3  ? 17.283  14.148  -13.334 1.00 58.68  ? 3   DA  D P     1 
ATOM   366  O OP1   . DA  B 2 3  ? 17.392  15.417  -14.102 1.00 52.83  ? 3   DA  D OP1   1 
ATOM   367  O OP2   . DA  B 2 3  ? 17.823  14.102  -11.924 1.00 57.92  ? 3   DA  D OP2   1 
ATOM   368  O "O5'" . DA  B 2 3  ? 15.793  13.720  -13.613 1.00 52.01  ? 3   DA  D "O5'" 1 
ATOM   369  C "C5'" . DA  B 2 3  ? 15.086  14.198  -14.765 1.00 51.46  ? 3   DA  D "C5'" 1 
ATOM   370  C "C4'" . DA  B 2 3  ? 13.709  13.582  -14.703 1.00 50.28  ? 3   DA  D "C4'" 1 
ATOM   371  O "O4'" . DA  B 2 3  ? 13.810  12.137  -14.806 1.00 48.92  ? 3   DA  D "O4'" 1 
ATOM   372  C "C3'" . DA  B 2 3  ? 12.944  13.836  -13.394 1.00 47.00  ? 3   DA  D "C3'" 1 
ATOM   373  O "O3'" . DA  B 2 3  ? 11.546  13.712  -13.635 1.00 53.17  ? 3   DA  D "O3'" 1 
ATOM   374  C "C2'" . DA  B 2 3  ? 13.430  12.682  -12.522 1.00 50.45  ? 3   DA  D "C2'" 1 
ATOM   375  C "C1'" . DA  B 2 3  ? 13.483  11.539  -13.540 1.00 50.76  ? 3   DA  D "C1'" 1 
ATOM   376  N N9    . DA  B 2 3  ? 14.437  10.482  -13.206 1.00 51.49  ? 3   DA  D N9    1 
ATOM   377  C C8    . DA  B 2 3  ? 15.696  10.544  -12.652 1.00 53.19  ? 3   DA  D C8    1 
ATOM   378  N N7    . DA  B 2 3  ? 16.253  9.360   -12.474 1.00 53.23  ? 3   DA  D N7    1 
ATOM   379  C C5    . DA  B 2 3  ? 15.324  8.478   -12.968 1.00 45.10  ? 3   DA  D C5    1 
ATOM   380  C C6    . DA  B 2 3  ? 15.329  7.085   -13.066 1.00 53.24  ? 3   DA  D C6    1 
ATOM   381  N N6    . DA  B 2 3  ? 16.343  6.344   -12.642 1.00 54.99  ? 3   DA  D N6    1 
ATOM   382  N N1    . DA  B 2 3  ? 14.227  6.481   -13.582 1.00 57.46  ? 3   DA  D N1    1 
ATOM   383  C C2    . DA  B 2 3  ? 13.220  7.257   -13.995 1.00 60.54  ? 3   DA  D C2    1 
ATOM   384  N N3    . DA  B 2 3  ? 13.106  8.589   -13.938 1.00 61.60  ? 3   DA  D N3    1 
ATOM   385  C C4    . DA  B 2 3  ? 14.196  9.144   -13.400 1.00 46.42  ? 3   DA  D C4    1 
ATOM   386  P P     . DA  B 2 4  ? 10.468  13.960  -12.459 1.00 55.24  ? 4   DA  D P     1 
ATOM   387  O OP1   . DA  B 2 4  ? 9.476   14.866  -13.095 1.00 46.95  ? 4   DA  D OP1   1 
ATOM   388  O OP2   . DA  B 2 4  ? 11.298  14.408  -11.306 1.00 47.07  ? 4   DA  D OP2   1 
ATOM   389  O "O5'" . DA  B 2 4  ? 9.839   12.513  -12.208 1.00 53.04  ? 4   DA  D "O5'" 1 
ATOM   390  C "C5'" . DA  B 2 4  ? 9.467   11.748  -13.366 1.00 54.45  ? 4   DA  D "C5'" 1 
ATOM   391  C "C4'" . DA  B 2 4  ? 9.060   10.363  -12.926 1.00 50.41  ? 4   DA  D "C4'" 1 
ATOM   392  O "O4'" . DA  B 2 4  ? 10.268  9.653   -12.614 1.00 51.47  ? 4   DA  D "O4'" 1 
ATOM   393  C "C3'" . DA  B 2 4  ? 8.175   10.272  -11.670 1.00 53.38  ? 4   DA  D "C3'" 1 
ATOM   394  O "O3'" . DA  B 2 4  ? 7.090   9.372   -11.857 1.00 61.53  ? 4   DA  D "O3'" 1 
ATOM   395  C "C2'" . DA  B 2 4  ? 9.117   9.744   -10.587 1.00 49.31  ? 4   DA  D "C2'" 1 
ATOM   396  C "C1'" . DA  B 2 4  ? 10.076  8.913   -11.408 1.00 52.05  ? 4   DA  D "C1'" 1 
ATOM   397  N N9    . DA  B 2 4  ? 11.400  8.748   -10.830 1.00 50.83  ? 4   DA  D N9    1 
ATOM   398  C C8    . DA  B 2 4  ? 12.331  9.683   -10.452 1.00 48.74  ? 4   DA  D C8    1 
ATOM   399  N N7    . DA  B 2 4  ? 13.461  9.165   -10.038 1.00 42.61  ? 4   DA  D N7    1 
ATOM   400  C C5    . DA  B 2 4  ? 13.269  7.805   -10.207 1.00 44.82  ? 4   DA  D C5    1 
ATOM   401  C C6    . DA  B 2 4  ? 14.091  6.709   -9.926  1.00 47.92  ? 4   DA  D C6    1 
ATOM   402  N N6    . DA  B 2 4  ? 15.315  6.825   -9.419  1.00 48.37  ? 4   DA  D N6    1 
ATOM   403  N N1    . DA  B 2 4  ? 13.606  5.481   -10.227 1.00 48.55  ? 4   DA  D N1    1 
ATOM   404  C C2    . DA  B 2 4  ? 12.366  5.391   -10.714 1.00 51.14  ? 4   DA  D C2    1 
ATOM   405  N N3    . DA  B 2 4  ? 11.494  6.354   -10.996 1.00 53.48  ? 4   DA  D N3    1 
ATOM   406  C C4    . DA  B 2 4  ? 12.032  7.546   -10.747 1.00 49.25  ? 4   DA  D C4    1 
ATOM   407  P P     . DT  B 2 5  ? 5.972   9.146   -10.723 1.00 61.30  ? 5   DT  D P     1 
ATOM   408  O OP1   . DT  B 2 5  ? 4.669   8.976   -11.427 1.00 59.74  ? 5   DT  D OP1   1 
ATOM   409  O OP2   . DT  B 2 5  ? 6.164   10.191  -9.679  1.00 55.37  ? 5   DT  D OP2   1 
ATOM   410  O "O5'" . DT  B 2 5  ? 6.447   7.702   -10.272 1.00 60.60  ? 5   DT  D "O5'" 1 
ATOM   411  C "C5'" . DT  B 2 5  ? 6.339   6.653   -11.274 1.00 64.05  ? 5   DT  D "C5'" 1 
ATOM   412  C "C4'" . DT  B 2 5  ? 6.609   5.371   -10.543 1.00 65.65  ? 5   DT  D "C4'" 1 
ATOM   413  O "O4'" . DT  B 2 5  ? 7.986   5.355   -10.117 1.00 60.54  ? 5   DT  D "O4'" 1 
ATOM   414  C "C3'" . DT  B 2 5  ? 5.776   5.233   -9.277  1.00 63.22  ? 5   DT  D "C3'" 1 
ATOM   415  O "O3'" . DT  B 2 5  ? 5.238   3.924   -9.264  1.00 73.71  ? 5   DT  D "O3'" 1 
ATOM   416  C "C2'" . DT  B 2 5  ? 6.777   5.466   -8.152  1.00 65.77  ? 5   DT  D "C2'" 1 
ATOM   417  C "C1'" . DT  B 2 5  ? 8.058   4.926   -8.769  1.00 60.67  ? 5   DT  D "C1'" 1 
ATOM   418  N N1    . DT  B 2 5  ? 9.355   5.404   -8.201  1.00 60.35  ? 5   DT  D N1    1 
ATOM   419  C C2    . DT  B 2 5  ? 10.327  4.459   -7.948  1.00 56.75  ? 5   DT  D C2    1 
ATOM   420  O O2    . DT  B 2 5  ? 10.174  3.271   -8.131  1.00 65.40  ? 5   DT  D O2    1 
ATOM   421  N N3    . DT  B 2 5  ? 11.514  4.933   -7.474  1.00 58.53  ? 5   DT  D N3    1 
ATOM   422  C C4    . DT  B 2 5  ? 11.860  6.239   -7.229  1.00 57.63  ? 5   DT  D C4    1 
ATOM   423  O O4    . DT  B 2 5  ? 13.014  6.493   -6.808  1.00 60.02  ? 5   DT  D O4    1 
ATOM   424  C C5    . DT  B 2 5  ? 10.813  7.199   -7.523  1.00 58.70  ? 5   DT  D C5    1 
ATOM   425  C C7    . DT  B 2 5  ? 11.101  8.657   -7.256  1.00 56.43  ? 5   DT  D C7    1 
ATOM   426  C C6    . DT  B 2 5  ? 9.630   6.748   -8.006  1.00 54.82  ? 5   DT  D C6    1 
ATOM   427  P P     . DT  B 2 6  ? 4.192   3.472   -8.126  1.00 78.65  ? 6   DT  D P     1 
ATOM   428  O OP1   . DT  B 2 6  ? 3.252   2.625   -8.909  1.00 78.53  ? 6   DT  D OP1   1 
ATOM   429  O OP2   . DT  B 2 6  ? 3.706   4.620   -7.304  1.00 69.10  ? 6   DT  D OP2   1 
ATOM   430  O "O5'" . DT  B 2 6  ? 5.018   2.567   -7.100  1.00 76.48  ? 6   DT  D "O5'" 1 
ATOM   431  C "C5'" . DT  B 2 6  ? 5.516   1.302   -7.611  1.00 80.51  ? 6   DT  D "C5'" 1 
ATOM   432  C "C4'" . DT  B 2 6  ? 6.515   0.738   -6.631  1.00 85.95  ? 6   DT  D "C4'" 1 
ATOM   433  O "O4'" . DT  B 2 6  ? 7.661   1.610   -6.529  1.00 77.87  ? 6   DT  D "O4'" 1 
ATOM   434  C "C3'" . DT  B 2 6  ? 5.985   0.580   -5.204  1.00 76.79  ? 6   DT  D "C3'" 1 
ATOM   435  O "O3'" . DT  B 2 6  ? 5.802   -0.779  -4.864  1.00 86.97  ? 6   DT  D "O3'" 1 
ATOM   436  C "C2'" . DT  B 2 6  ? 7.093   1.100   -4.303  1.00 83.05  ? 6   DT  D "C2'" 1 
ATOM   437  C "C1'" . DT  B 2 6  ? 8.245   1.392   -5.253  1.00 86.23  ? 6   DT  D "C1'" 1 
ATOM   438  N N1    . DT  B 2 6  ? 9.000   2.609   -4.915  1.00 76.44  ? 6   DT  D N1    1 
ATOM   439  C C2    . DT  B 2 6  ? 10.302  2.496   -4.471  1.00 68.92  ? 6   DT  D C2    1 
ATOM   440  O O2    . DT  B 2 6  ? 10.889  1.425   -4.339  1.00 69.22  ? 6   DT  D O2    1 
ATOM   441  N N3    . DT  B 2 6  ? 10.910  3.693   -4.214  1.00 64.34  ? 6   DT  D N3    1 
ATOM   442  C C4    . DT  B 2 6  ? 10.363  4.948   -4.360  1.00 61.07  ? 6   DT  D C4    1 
ATOM   443  O O4    . DT  B 2 6  ? 11.041  5.929   -4.108  1.00 62.46  ? 6   DT  D O4    1 
ATOM   444  C C5    . DT  B 2 6  ? 8.984   4.986   -4.781  1.00 68.35  ? 6   DT  D C5    1 
ATOM   445  C C7    . DT  B 2 6  ? 8.294   6.312   -4.928  1.00 77.62  ? 6   DT  D C7    1 
ATOM   446  C C6    . DT  B 2 6  ? 8.379   3.826   -5.047  1.00 75.68  ? 6   DT  D C6    1 
ATOM   447  P P     . DG  B 2 7  ? 4.840   -1.168  -3.640  1.00 84.21  ? 7   DG  D P     1 
ATOM   448  O OP1   . DG  B 2 7  ? 4.173   -2.448  -3.984  1.00 90.80  ? 7   DG  D OP1   1 
ATOM   449  O OP2   . DG  B 2 7  ? 4.085   -0.012  -3.080  1.00 73.84  ? 7   DG  D OP2   1 
ATOM   450  O "O5'" . DG  B 2 7  ? 5.922   -1.431  -2.518  1.00 76.22  ? 7   DG  D "O5'" 1 
ATOM   451  C "C5'" . DG  B 2 7  ? 6.777   -2.574  -2.655  1.00 78.38  ? 7   DG  D "C5'" 1 
ATOM   452  C "C4'" . DG  B 2 7  ? 7.760   -2.438  -1.530  1.00 76.13  ? 7   DG  D "C4'" 1 
ATOM   453  O "O4'" . DG  B 2 7  ? 8.476   -1.195  -1.707  1.00 65.76  ? 7   DG  D "O4'" 1 
ATOM   454  C "C3'" . DG  B 2 7  ? 7.073   -2.360  -0.170  1.00 73.42  ? 7   DG  D "C3'" 1 
ATOM   455  O "O3'" . DG  B 2 7  ? 7.704   -3.321  0.637   1.00 70.35  ? 7   DG  D "O3'" 1 
ATOM   456  C "C2'" . DG  B 2 7  ? 7.328   -0.928  0.313   1.00 66.33  ? 7   DG  D "C2'" 1 
ATOM   457  C "C1'" . DG  B 2 7  ? 8.568   -0.519  -0.468  1.00 61.75  ? 7   DG  D "C1'" 1 
ATOM   458  N N9    . DG  B 2 7  ? 8.676   0.910   -0.750  1.00 65.11  ? 7   DG  D N9    1 
ATOM   459  C C8    . DG  B 2 7  ? 7.748   1.848   -1.146  1.00 69.63  ? 7   DG  D C8    1 
ATOM   460  N N7    . DG  B 2 7  ? 8.248   3.059   -1.273  1.00 66.02  ? 7   DG  D N7    1 
ATOM   461  C C5    . DG  B 2 7  ? 9.587   2.903   -0.929  1.00 65.69  ? 7   DG  D C5    1 
ATOM   462  C C6    . DG  B 2 7  ? 10.638  3.845   -0.882  1.00 63.04  ? 7   DG  D C6    1 
ATOM   463  O O6    . DG  B 2 7  ? 10.592  5.059   -1.108  1.00 68.16  ? 7   DG  D O6    1 
ATOM   464  N N1    . DG  B 2 7  ? 11.846  3.256   -0.498  1.00 57.86  ? 7   DG  D N1    1 
ATOM   465  C C2    . DG  B 2 7  ? 12.009  1.938   -0.159  1.00 57.18  ? 7   DG  D C2    1 
ATOM   466  N N2    . DG  B 2 7  ? 13.237  1.558   0.205   1.00 56.57  ? 7   DG  D N2    1 
ATOM   467  N N3    . DG  B 2 7  ? 11.039  1.033   -0.236  1.00 63.76  ? 7   DG  D N3    1 
ATOM   468  C C4    . DG  B 2 7  ? 9.860   1.588   -0.609  1.00 68.18  ? 7   DG  D C4    1 
ATOM   469  P P     . DC  B 2 8  ? 7.176   -3.644  2.113   1.00 70.55  ? 8   DC  D P     1 
ATOM   470  O OP1   . DC  B 2 8  ? 7.390   -5.083  1.778   1.00 73.50  ? 8   DC  D OP1   1 
ATOM   471  O OP2   . DC  B 2 8  ? 5.850   -3.061  2.451   1.00 69.23  ? 8   DC  D OP2   1 
ATOM   472  O "O5'" . DC  B 2 8  ? 8.277   -2.968  3.045   1.00 71.32  ? 8   DC  D "O5'" 1 
ATOM   473  C "C5'" . DC  B 2 8  ? 9.649   -3.279  2.723   1.00 61.85  ? 8   DC  D "C5'" 1 
ATOM   474  C "C4'" . DC  B 2 8  ? 10.490  -2.235  3.388   1.00 63.93  ? 8   DC  D "C4'" 1 
ATOM   475  O "O4'" . DC  B 2 8  ? 10.279  -0.965  2.752   1.00 66.05  ? 8   DC  D "O4'" 1 
ATOM   476  C "C3'" . DC  B 2 8  ? 10.135  -1.979  4.836   1.00 62.76  ? 8   DC  D "C3'" 1 
ATOM   477  O "O3'" . DC  B 2 8  ? 11.001  -2.837  5.542   1.00 56.29  ? 8   DC  D "O3'" 1 
ATOM   478  C "C2'" . DC  B 2 8  ? 10.388  -0.478  5.018   1.00 64.46  ? 8   DC  D "C2'" 1 
ATOM   479  C "C1'" . DC  B 2 8  ? 10.792  -0.000  3.626   1.00 63.77  ? 8   DC  D "C1'" 1 
ATOM   480  N N1    . DC  B 2 8  ? 10.240  1.295   3.172   1.00 58.33  ? 8   DC  D N1    1 
ATOM   481  C C2    . DC  B 2 8  ? 11.096  2.403   3.138   1.00 55.67  ? 8   DC  D C2    1 
ATOM   482  O O2    . DC  B 2 8  ? 12.268  2.251   3.495   1.00 63.47  ? 8   DC  D O2    1 
ATOM   483  N N3    . DC  B 2 8  ? 10.644  3.594   2.672   1.00 50.74  ? 8   DC  D N3    1 
ATOM   484  C C4    . DC  B 2 8  ? 9.370   3.703   2.281   1.00 60.72  ? 8   DC  D C4    1 
ATOM   485  N N4    . DC  B 2 8  ? 8.978   4.896   1.857   1.00 60.05  ? 8   DC  D N4    1 
ATOM   486  C C5    . DC  B 2 8  ? 8.464   2.579   2.315   1.00 56.46  ? 8   DC  D C5    1 
ATOM   487  C C6    . DC  B 2 8  ? 8.953   1.398   2.730   1.00 55.16  ? 8   DC  D C6    1 
ATOM   488  P P     . DC  B 2 9  ? 11.200  -2.678  7.124   1.00 68.28  ? 9   DC  D P     1 
ATOM   489  O OP1   . DC  B 2 9  ? 12.040  -3.858  7.476   1.00 61.73  ? 9   DC  D OP1   1 
ATOM   490  O OP2   . DC  B 2 9  ? 9.864   -2.472  7.778   1.00 59.19  ? 9   DC  D OP2   1 
ATOM   491  O "O5'" . DC  B 2 9  ? 11.998  -1.315  7.412   1.00 68.19  ? 9   DC  D "O5'" 1 
ATOM   492  C "C5'" . DC  B 2 9  ? 13.444  -1.206  7.142   1.00 66.25  ? 9   DC  D "C5'" 1 
ATOM   493  C "C4'" . DC  B 2 9  ? 13.873  0.220   7.392   1.00 60.11  ? 9   DC  D "C4'" 1 
ATOM   494  O "O4'" . DC  B 2 9  ? 12.990  1.093   6.675   1.00 55.01  ? 9   DC  D "O4'" 1 
ATOM   495  C "C3'" . DC  B 2 9  ? 13.750  0.716   8.828   1.00 61.71  ? 9   DC  D "C3'" 1 
ATOM   496  O "O3'" . DC  B 2 9  ? 15.002  0.665   9.492   1.00 66.61  ? 9   DC  D "O3'" 1 
ATOM   497  C "C2'" . DC  B 2 9  ? 13.270  2.161   8.693   1.00 65.77  ? 9   DC  D "C2'" 1 
ATOM   498  C "C1'" . DC  B 2 9  ? 13.122  2.385   7.204   1.00 55.84  ? 9   DC  D "C1'" 1 
ATOM   499  N N1    . DC  B 2 9  ? 11.923  3.128   6.743   1.00 56.91  ? 9   DC  D N1    1 
ATOM   500  C C2    . DC  B 2 9  ? 12.022  4.474   6.352   1.00 61.83  ? 9   DC  D C2    1 
ATOM   501  O O2    . DC  B 2 9  ? 13.083  5.089   6.513   1.00 61.00  ? 9   DC  D O2    1 
ATOM   502  N N3    . DC  B 2 9  ? 10.931  5.112   5.866   1.00 61.68  ? 9   DC  D N3    1 
ATOM   503  C C4    . DC  B 2 9  ? 9.777   4.455   5.753   1.00 56.58  ? 9   DC  D C4    1 
ATOM   504  N N4    . DC  B 2 9  ? 8.742   5.113   5.261   1.00 53.20  ? 9   DC  D N4    1 
ATOM   505  C C5    . DC  B 2 9  ? 9.680   3.073   6.064   1.00 56.68  ? 9   DC  D C5    1 
ATOM   506  C C6    . DC  B 2 9  ? 10.772  2.454   6.527   1.00 51.32  ? 9   DC  D C6    1 
ATOM   507  P P     . DC  B 2 10 ? 15.151  1.084   11.038  1.00 75.62  ? 10  DC  D P     1 
ATOM   508  O OP1   . DC  B 2 10 ? 16.511  0.666   11.474  1.00 71.10  ? 10  DC  D OP1   1 
ATOM   509  O OP2   . DC  B 2 10 ? 14.003  0.515   11.814  1.00 82.60  ? 10  DC  D OP2   1 
ATOM   510  O "O5'" . DC  B 2 10 ? 15.041  2.686   10.992  1.00 71.34  ? 10  DC  D "O5'" 1 
ATOM   511  C "C5'" . DC  B 2 10 ? 15.993  3.483   10.203  1.00 70.93  ? 10  DC  D "C5'" 1 
ATOM   512  C "C4'" . DC  B 2 10 ? 15.729  4.959   10.419  1.00 68.73  ? 10  DC  D "C4'" 1 
ATOM   513  O "O4'" . DC  B 2 10 ? 14.524  5.380   9.736   1.00 65.27  ? 10  DC  D "O4'" 1 
ATOM   514  C "C3'" . DC  B 2 10 ? 15.534  5.390   11.865  1.00 73.04  ? 10  DC  D "C3'" 1 
ATOM   515  O "O3'" . DC  B 2 10 ? 16.432  6.453   12.126  1.00 77.24  ? 10  DC  D "O3'" 1 
ATOM   516  C "C2'" . DC  B 2 10 ? 14.085  5.868   11.944  1.00 74.25  ? 10  DC  D "C2'" 1 
ATOM   517  C "C1'" . DC  B 2 10 ? 13.800  6.310   10.525  1.00 64.18  ? 10  DC  D "C1'" 1 
ATOM   518  N N1    . DC  B 2 10 ? 12.395  6.215   10.046  1.00 62.66  ? 10  DC  D N1    1 
ATOM   519  C C2    . DC  B 2 10 ? 11.783  7.312   9.417   1.00 56.00  ? 10  DC  D C2    1 
ATOM   520  O O2    . DC  B 2 10 ? 12.346  8.411   9.412   1.00 66.53  ? 10  DC  D O2    1 
ATOM   521  N N3    . DC  B 2 10 ? 10.549  7.176   8.895   1.00 57.01  ? 10  DC  D N3    1 
ATOM   522  C C4    . DC  B 2 10 ? 9.904   5.998   8.998   1.00 63.78  ? 10  DC  D C4    1 
ATOM   523  N N4    . DC  B 2 10 ? 8.672   5.908   8.501   1.00 60.97  ? 10  DC  D N4    1 
ATOM   524  C C5    . DC  B 2 10 ? 10.515  4.864   9.604   1.00 54.71  ? 10  DC  D C5    1 
ATOM   525  C C6    . DC  B 2 10 ? 11.735  5.023   10.135  1.00 57.02  ? 10  DC  D C6    1 
ATOM   526  P P     . DG  B 2 11 ? 16.808  6.865   13.635  1.00 81.84  ? 11  DG  D P     1 
ATOM   527  O OP1   . DG  B 2 11 ? 18.217  7.354   13.580  1.00 76.32  ? 11  DG  D OP1   1 
ATOM   528  O OP2   . DG  B 2 11 ? 16.466  5.770   14.580  1.00 82.75  ? 11  DG  D OP2   1 
ATOM   529  O "O5'" . DG  B 2 11 ? 15.754  8.051   13.809  1.00 78.55  ? 11  DG  D "O5'" 1 
ATOM   530  C "C5'" . DG  B 2 11 ? 15.762  9.073   12.776  1.00 82.44  ? 11  DG  D "C5'" 1 
ATOM   531  C "C4'" . DG  B 2 11 ? 14.782  10.168  13.101  1.00 85.74  ? 11  DG  D "C4'" 1 
ATOM   532  O "O4'" . DG  B 2 11 ? 13.493  9.862   12.526  1.00 84.26  ? 11  DG  D "O4'" 1 
ATOM   533  C "C3'" . DG  B 2 11 ? 14.533  10.384  14.590  1.00 86.50  ? 11  DG  D "C3'" 1 
ATOM   534  O "O3'" . DG  B 2 11 ? 14.260  11.752  14.774  1.00 85.95  ? 11  DG  D "O3'" 1 
ATOM   535  C "C2'" . DG  B 2 11 ? 13.278  9.566   14.852  1.00 81.10  ? 11  DG  D "C2'" 1 
ATOM   536  C "C1'" . DG  B 2 11 ? 12.514  9.802   13.565  1.00 77.30  ? 11  DG  D "C1'" 1 
ATOM   537  N N9    . DG  B 2 11 ? 11.551  8.761   13.208  1.00 68.96  ? 11  DG  D N9    1 
ATOM   538  C C8    . DG  B 2 11 ? 11.479  7.404   13.403  1.00 62.89  ? 11  DG  D C8    1 
ATOM   539  N N7    . DG  B 2 11 ? 10.408  6.868   12.858  1.00 65.77  ? 11  DG  D N7    1 
ATOM   540  C C5    . DG  B 2 11 ? 9.744   7.939   12.270  1.00 56.44  ? 11  DG  D C5    1 
ATOM   541  C C6    . DG  B 2 11 ? 8.540   7.988   11.528  1.00 64.89  ? 11  DG  D C6    1 
ATOM   542  O O6    . DG  B 2 11 ? 7.772   7.052   11.241  1.00 66.44  ? 11  DG  D O6    1 
ATOM   543  N N1    . DG  B 2 11 ? 8.245   9.301   11.130  1.00 63.85  ? 11  DG  D N1    1 
ATOM   544  C C2    . DG  B 2 11 ? 9.028   10.404  11.387  1.00 72.18  ? 11  DG  D C2    1 
ATOM   545  N N2    . DG  B 2 11 ? 8.641   11.589  10.900  1.00 81.62  ? 11  DG  D N2    1 
ATOM   546  N N3    . DG  B 2 11 ? 10.171  10.350  12.050  1.00 71.67  ? 11  DG  D N3    1 
ATOM   547  C C4    . DG  B 2 11 ? 10.443  9.102   12.484  1.00 64.19  ? 11  DG  D C4    1 
ATOM   548  P P     . DT  B 2 12 ? 14.169  12.368  16.246  1.00 92.16  ? 12  DT  D P     1 
ATOM   549  O OP1   . DT  B 2 12 ? 15.138  13.484  16.061  1.00 89.08  ? 12  DT  D OP1   1 
ATOM   550  O OP2   . DT  B 2 12 ? 14.398  11.299  17.274  1.00 83.00  ? 12  DT  D OP2   1 
ATOM   551  O "O5'" . DT  B 2 12 ? 12.669  12.911  16.229  1.00 82.88  ? 12  DT  D "O5'" 1 
ATOM   552  C "C5'" . DT  B 2 12 ? 12.329  13.802  15.153  1.00 89.20  ? 12  DT  D "C5'" 1 
ATOM   553  C "C4'" . DT  B 2 12 ? 10.834  13.845  15.026  1.00 92.59  ? 12  DT  D "C4'" 1 
ATOM   554  O "O4'" . DT  B 2 12 ? 10.334  12.567  14.589  1.00 90.01  ? 12  DT  D "O4'" 1 
ATOM   555  C "C3'" . DT  B 2 12 ? 10.114  14.129  16.341  1.00 97.57  ? 12  DT  D "C3'" 1 
ATOM   556  O "O3'" . DT  B 2 12 ? 9.669   15.472  16.334  1.00 102.21 ? 12  DT  D "O3'" 1 
ATOM   557  C "C2'" . DT  B 2 12 ? 8.938   13.154  16.362  1.00 90.81  ? 12  DT  D "C2'" 1 
ATOM   558  C "C1'" . DT  B 2 12 ? 8.971   12.525  14.979  1.00 83.33  ? 12  DT  D "C1'" 1 
ATOM   559  N N1    . DT  B 2 12 ? 8.490   11.131  14.935  1.00 68.51  ? 12  DT  D N1    1 
ATOM   560  C C2    . DT  B 2 12 ? 7.319   10.885  14.248  1.00 74.35  ? 12  DT  D C2    1 
ATOM   561  O O2    . DT  B 2 12 ? 6.694   11.749  13.649  1.00 80.79  ? 12  DT  D O2    1 
ATOM   562  N N3    . DT  B 2 12 ? 6.897   9.586   14.265  1.00 69.54  ? 12  DT  D N3    1 
ATOM   563  C C4    . DT  B 2 12 ? 7.530   8.525   14.866  1.00 68.01  ? 12  DT  D C4    1 
ATOM   564  O O4    . DT  B 2 12 ? 7.016   7.409   14.763  1.00 71.07  ? 12  DT  D O4    1 
ATOM   565  C C5    . DT  B 2 12 ? 8.747   8.851   15.583  1.00 63.72  ? 12  DT  D C5    1 
ATOM   566  C C7    . DT  B 2 12 ? 9.506   7.745   16.265  1.00 69.37  ? 12  DT  D C7    1 
ATOM   567  C C6    . DT  B 2 12 ? 9.161   10.129  15.592  1.00 59.64  ? 12  DT  D C6    1 
ATOM   568  P P     . DT  B 2 13 ? 8.987   16.091  17.649  1.00 102.28 ? 13  DT  D P     1 
ATOM   569  O OP1   . DT  B 2 13 ? 9.276   17.552  17.751  1.00 102.35 ? 13  DT  D OP1   1 
ATOM   570  O OP2   . DT  B 2 13 ? 9.346   15.214  18.804  1.00 92.31  ? 13  DT  D OP2   1 
ATOM   571  O "O5'" . DT  B 2 13 ? 7.462   15.914  17.189  1.00 94.48  ? 13  DT  D "O5'" 1 
ATOM   572  C "C5'" . DT  B 2 13 ? 7.102   16.074  15.778  1.00 84.90  ? 13  DT  D "C5'" 1 
ATOM   573  C "C4'" . DT  B 2 13 ? 5.712   15.511  15.546  1.00 86.97  ? 13  DT  D "C4'" 1 
ATOM   574  O "O4'" . DT  B 2 13 ? 5.730   14.065  15.390  1.00 73.59  ? 13  DT  D "O4'" 1 
ATOM   575  C "C3'" . DT  B 2 13 ? 4.712   15.782  16.681  1.00 82.66  ? 13  DT  D "C3'" 1 
ATOM   576  O "O3'" . DT  B 2 13 ? 3.441   16.040  16.107  1.00 81.54  ? 13  DT  D "O3'" 1 
ATOM   577  C "C2'" . DT  B 2 13 ? 4.643   14.450  17.401  1.00 79.11  ? 13  DT  D "C2'" 1 
ATOM   578  C "C1'" . DT  B 2 13 ? 4.699   13.507  16.205  1.00 69.50  ? 13  DT  D "C1'" 1 
ATOM   579  N N1    . DT  B 2 13 ? 5.012   12.110  16.571  1.00 66.68  ? 13  DT  D N1    1 
ATOM   580  C C2    . DT  B 2 13 ? 4.208   11.081  16.106  1.00 70.54  ? 13  DT  D C2    1 
ATOM   581  O O2    . DT  B 2 13 ? 3.261   11.250  15.339  1.00 66.94  ? 13  DT  D O2    1 
ATOM   582  N N3    . DT  B 2 13 ? 4.568   9.824   16.558  1.00 69.05  ? 13  DT  D N3    1 
ATOM   583  C C4    . DT  B 2 13 ? 5.630   9.501   17.392  1.00 67.26  ? 13  DT  D C4    1 
ATOM   584  O O4    . DT  B 2 13 ? 5.852   8.325   17.685  1.00 65.20  ? 13  DT  D O4    1 
ATOM   585  C C5    . DT  B 2 13 ? 6.419   10.626  17.844  1.00 68.65  ? 13  DT  D C5    1 
ATOM   586  C C7    . DT  B 2 13 ? 7.586   10.378  18.752  1.00 63.70  ? 13  DT  D C7    1 
ATOM   587  C C6    . DT  B 2 13 ? 6.068   11.856  17.432  1.00 70.68  ? 13  DT  D C6    1 
ATOM   588  P P     . DT  B 2 14 ? 2.311   16.812  16.924  1.00 89.34  ? 14  DT  D P     1 
ATOM   589  O OP1   . DT  B 2 14 ? 1.732   17.913  16.102  1.00 93.97  ? 14  DT  D OP1   1 
ATOM   590  O OP2   . DT  B 2 14 ? 2.924   17.104  18.256  1.00 84.04  ? 14  DT  D OP2   1 
ATOM   591  O "O5'" . DT  B 2 14 ? 1.242   15.633  16.863  1.00 90.85  ? 14  DT  D "O5'" 1 
ATOM   592  C "C5'" . DT  B 2 14 ? 0.738   15.259  15.563  1.00 85.11  ? 14  DT  D "C5'" 1 
ATOM   593  C "C4'" . DT  B 2 14 ? -0.297  14.175  15.748  1.00 91.50  ? 14  DT  D "C4'" 1 
ATOM   594  O "O4'" . DT  B 2 14 ? 0.327   12.910  16.066  1.00 80.47  ? 14  DT  D "O4'" 1 
ATOM   595  C "C3'" . DT  B 2 14 ? -1.301  14.412  16.873  1.00 90.93  ? 14  DT  D "C3'" 1 
ATOM   596  O "O3'" . DT  B 2 14 ? -2.513  13.866  16.394  1.00 88.26  ? 14  DT  D "O3'" 1 
ATOM   597  C "C2'" . DT  B 2 14 ? -0.774  13.576  18.031  1.00 85.21  ? 14  DT  D "C2'" 1 
ATOM   598  C "C1'" . DT  B 2 14 ? -0.248  12.376  17.254  1.00 77.98  ? 14  DT  D "C1'" 1 
ATOM   599  N N1    . DT  B 2 14 ? 0.778   11.559  17.938  1.00 68.88  ? 14  DT  D N1    1 
ATOM   600  C C2    . DT  B 2 14 ? 0.652   10.186  17.852  1.00 67.29  ? 14  DT  D C2    1 
ATOM   601  O O2    . DT  B 2 14 ? -0.255  9.636   17.240  1.00 70.18  ? 14  DT  D O2    1 
ATOM   602  N N3    . DT  B 2 14 ? 1.607   9.467   18.524  1.00 66.66  ? 14  DT  D N3    1 
ATOM   603  C C4    . DT  B 2 14 ? 2.661   9.971   19.257  1.00 69.27  ? 14  DT  D C4    1 
ATOM   604  O O4    . DT  B 2 14 ? 3.428   9.194   19.817  1.00 68.10  ? 14  DT  D O4    1 
ATOM   605  C C5    . DT  B 2 14 ? 2.734   11.418  19.327  1.00 72.88  ? 14  DT  D C5    1 
ATOM   606  C C7    . DT  B 2 14 ? 3.828   12.037  20.149  1.00 71.78  ? 14  DT  D C7    1 
ATOM   607  C C6    . DT  B 2 14 ? 1.799   12.137  18.670  1.00 70.14  ? 14  DT  D C6    1 
ATOM   608  P P     . DA  B 2 15 ? -3.909  14.314  17.028  1.00 90.15  ? 15  DA  D P     1 
ATOM   609  O OP1   . DA  B 2 15 ? -4.897  14.479  15.921  1.00 91.44  ? 15  DA  D OP1   1 
ATOM   610  O OP2   . DA  B 2 15 ? -3.511  15.478  17.873  1.00 89.83  ? 15  DA  D OP2   1 
ATOM   611  O "O5'" . DA  B 2 15 ? -4.415  13.062  17.884  1.00 86.14  ? 15  DA  D "O5'" 1 
ATOM   612  C "C5'" . DA  B 2 15 ? -4.773  11.831  17.213  1.00 86.00  ? 15  DA  D "C5'" 1 
ATOM   613  C "C4'" . DA  B 2 15 ? -4.664  10.725  18.223  1.00 84.42  ? 15  DA  D "C4'" 1 
ATOM   614  O "O4'" . DA  B 2 15 ? -3.284  10.582  18.635  1.00 85.00  ? 15  DA  D "O4'" 1 
ATOM   615  C "C3'" . DA  B 2 15 ? -5.454  10.983  19.507  1.00 91.55  ? 15  DA  D "C3'" 1 
ATOM   616  O "O3'" . DA  B 2 15 ? -6.142  9.818   19.905  1.00 98.19  ? 15  DA  D "O3'" 1 
ATOM   617  C "C2'" . DA  B 2 15 ? -4.374  11.270  20.537  1.00 89.75  ? 15  DA  D "C2'" 1 
ATOM   618  C "C1'" . DA  B 2 15 ? -3.316  10.314  20.034  1.00 84.72  ? 15  DA  D "C1'" 1 
ATOM   619  N N9    . DA  B 2 15 ? -2.006  10.477  20.659  1.00 80.72  ? 15  DA  D N9    1 
ATOM   620  C C8    . DA  B 2 15 ? -1.333  11.604  21.087  1.00 80.93  ? 15  DA  D C8    1 
ATOM   621  N N7    . DA  B 2 15 ? -0.188  11.329  21.660  1.00 77.83  ? 15  DA  D N7    1 
ATOM   622  C C5    . DA  B 2 15 ? -0.133  9.941   21.652  1.00 68.18  ? 15  DA  D C5    1 
ATOM   623  C C6    . DA  B 2 15 ? 0.815   9.032   22.138  1.00 66.79  ? 15  DA  D C6    1 
ATOM   624  N N6    . DA  B 2 15 ? 1.938   9.402   22.736  1.00 66.02  ? 15  DA  D N6    1 
ATOM   625  N N1    . DA  B 2 15 ? 0.551   7.704   22.000  1.00 64.98  ? 15  DA  D N1    1 
ATOM   626  C C2    . DA  B 2 15 ? -0.597  7.326   21.421  1.00 59.73  ? 15  DA  D C2    1 
ATOM   627  N N3    . DA  B 2 15 ? -1.546  8.092   20.896  1.00 66.28  ? 15  DA  D N3    1 
ATOM   628  C C4    . DA  B 2 15 ? -1.257  9.400   21.060  1.00 69.43  ? 15  DA  D C4    1 
ATOM   629  P P     . DG  B 2 16 ? -7.701  9.704   19.590  1.00 99.28  ? 16  DG  D P     1 
ATOM   630  O OP1   . DG  B 2 16 ? -7.841  9.627   18.104  1.00 95.53  ? 16  DG  D OP1   1 
ATOM   631  O OP2   . DG  B 2 16 ? -8.347  10.814  20.337  1.00 109.51 ? 16  DG  D OP2   1 
ATOM   632  O "O5'" . DG  B 2 16 ? -7.903  8.250   20.217  1.00 98.33  ? 16  DG  D "O5'" 1 
ATOM   633  C "C5'" . DG  B 2 16 ? -7.739  7.123   19.305  1.00 95.10  ? 16  DG  D "C5'" 1 
ATOM   634  C "C4'" . DG  B 2 16 ? -7.298  5.907   20.075  1.00 88.49  ? 16  DG  D "C4'" 1 
ATOM   635  O "O4'" . DG  B 2 16 ? -6.045  6.174   20.735  1.00 80.07  ? 16  DG  D "O4'" 1 
ATOM   636  C "C3'" . DG  B 2 16 ? -8.253  5.469   21.177  1.00 88.44  ? 16  DG  D "C3'" 1 
ATOM   637  O "O3'" . DG  B 2 16 ? -8.245  4.046   21.189  1.00 90.07  ? 16  DG  D "O3'" 1 
ATOM   638  C "C2'" . DG  B 2 16 ? -7.631  6.073   22.439  1.00 88.71  ? 16  DG  D "C2'" 1 
ATOM   639  C "C1'" . DG  B 2 16 ? -6.161  5.895   22.128  1.00 77.58  ? 16  DG  D "C1'" 1 
ATOM   640  N N9    . DG  B 2 16 ? -5.171  6.790   22.709  1.00 77.30  ? 16  DG  D N9    1 
ATOM   641  C C8    . DG  B 2 16 ? -5.055  8.140   22.503  1.00 84.62  ? 16  DG  D C8    1 
ATOM   642  N N7    . DG  B 2 16 ? -3.938  8.640   22.986  1.00 85.40  ? 16  DG  D N7    1 
ATOM   643  C C5    . DG  B 2 16 ? -3.250  7.544   23.478  1.00 76.34  ? 16  DG  D C5    1 
ATOM   644  C C6    . DG  B 2 16 ? -1.985  7.467   24.104  1.00 82.53  ? 16  DG  D C6    1 
ATOM   645  O O6    . DG  B 2 16 ? -1.208  8.391   24.376  1.00 79.28  ? 16  DG  D O6    1 
ATOM   646  N N1    . DG  B 2 16 ? -1.640  6.145   24.397  1.00 79.29  ? 16  DG  D N1    1 
ATOM   647  C C2    . DG  B 2 16 ? -2.426  5.041   24.141  1.00 75.49  ? 16  DG  D C2    1 
ATOM   648  N N2    . DG  B 2 16 ? -1.955  3.845   24.537  1.00 73.07  ? 16  DG  D N2    1 
ATOM   649  N N3    . DG  B 2 16 ? -3.619  5.114   23.546  1.00 74.26  ? 16  DG  D N3    1 
ATOM   650  C C4    . DG  B 2 16 ? -3.971  6.390   23.264  1.00 78.87  ? 16  DG  D C4    1 
ATOM   651  N N     . ALA C 3 1  ? -5.427  11.730  7.361   1.00 153.94 ? 231 ALA A N     1 
ATOM   652  C CA    . ALA C 3 1  ? -6.890  11.663  7.115   1.00 152.04 ? 231 ALA A CA    1 
ATOM   653  C C     . ALA C 3 1  ? -7.606  11.158  8.378   1.00 136.03 ? 231 ALA A C     1 
ATOM   654  O O     . ALA C 3 1  ? -6.988  11.076  9.440   1.00 118.19 ? 231 ALA A O     1 
ATOM   655  C CB    . ALA C 3 1  ? -7.131  10.799  5.885   1.00 148.35 ? 231 ALA A CB    1 
ATOM   656  N N     . PRO C 3 2  ? -8.922  10.818  8.327   1.00 149.94 ? 232 PRO A N     1 
ATOM   657  C CA    . PRO C 3 2  ? -9.688  10.452  9.527   1.00 130.11 ? 232 PRO A CA    1 
ATOM   658  C C     . PRO C 3 2  ? -9.110  9.532   10.601  1.00 120.75 ? 232 PRO A C     1 
ATOM   659  O O     . PRO C 3 2  ? -9.715  9.438   11.663  1.00 140.01 ? 232 PRO A O     1 
ATOM   660  C CB    . PRO C 3 2  ? -10.942 9.818   8.898   1.00 131.11 ? 232 PRO A CB    1 
ATOM   661  C CG    . PRO C 3 2  ? -11.176 10.638  7.661   1.00 140.36 ? 232 PRO A CG    1 
ATOM   662  C CD    . PRO C 3 2  ? -9.773  10.853  7.122   1.00 147.14 ? 232 PRO A CD    1 
ATOM   663  N N     . ARG C 3 3  ? -7.992  8.839   10.328  1.00 105.06 ? 233 ARG A N     1 
ATOM   664  C CA    . ARG C 3 3  ? -7.240  8.101   11.344  1.00 98.93  ? 233 ARG A CA    1 
ATOM   665  C C     . ARG C 3 3  ? -7.966  6.812   11.713  1.00 91.73  ? 233 ARG A C     1 
ATOM   666  O O     . ARG C 3 3  ? -9.156  6.824   11.999  1.00 88.86  ? 233 ARG A O     1 
ATOM   667  C CB    . ARG C 3 3  ? -6.975  8.867   12.649  1.00 95.85  ? 233 ARG A CB    1 
ATOM   668  C CG    . ARG C 3 3  ? -6.140  8.103   13.668  1.00 86.68  ? 233 ARG A CG    1 
ATOM   669  C CD    . ARG C 3 3  ? -5.386  9.047   14.605  1.00 84.61  ? 233 ARG A CD    1 
ATOM   670  N NE    . ARG C 3 3  ? -4.390  8.214   15.290  1.00 83.95  ? 233 ARG A NE    1 
ATOM   671  C CZ    . ARG C 3 3  ? -3.058  8.297   15.171  1.00 89.00  ? 233 ARG A CZ    1 
ATOM   672  N NH1   . ARG C 3 3  ? -2.472  9.385   14.695  1.00 85.36  ? 233 ARG A NH1   1 
ATOM   673  N NH2   . ARG C 3 3  ? -2.300  7.289   15.568  1.00 85.97  ? 233 ARG A NH2   1 
ATOM   674  N N     . LYS C 3 4  ? -7.224  5.706   11.731  1.00 87.89  ? 234 LYS A N     1 
ATOM   675  C CA    . LYS C 3 4  ? -7.839  4.394   11.819  1.00 94.96  ? 234 LYS A CA    1 
ATOM   676  C C     . LYS C 3 4  ? -7.644  3.835   13.231  1.00 84.72  ? 234 LYS A C     1 
ATOM   677  O O     . LYS C 3 4  ? -6.723  4.226   13.946  1.00 68.81  ? 234 LYS A O     1 
ATOM   678  C CB    . LYS C 3 4  ? -7.349  3.529   10.645  1.00 107.73 ? 234 LYS A CB    1 
ATOM   679  C CG    . LYS C 3 4  ? -6.392  2.362   10.898  1.00 117.72 ? 234 LYS A CG    1 
ATOM   680  C CD    . LYS C 3 4  ? -7.025  1.047   11.365  1.00 135.77 ? 234 LYS A CD    1 
ATOM   681  C CE    . LYS C 3 4  ? -8.137  0.494   10.503  1.00 142.02 ? 234 LYS A CE    1 
ATOM   682  N NZ    . LYS C 3 4  ? -7.733  0.263   9.111   1.00 138.45 ? 234 LYS A NZ    1 
ATOM   683  N N     . ALA C 3 5  ? -8.547  2.904   13.586  1.00 89.67  ? 235 ALA A N     1 
ATOM   684  C CA    . ALA C 3 5  ? -8.714  2.347   14.923  1.00 80.52  ? 235 ALA A CA    1 
ATOM   685  C C     . ALA C 3 5  ? -7.407  1.752   15.428  1.00 76.70  ? 235 ALA A C     1 
ATOM   686  O O     . ALA C 3 5  ? -6.736  1.003   14.712  1.00 90.25  ? 235 ALA A O     1 
ATOM   687  C CB    . ALA C 3 5  ? -9.799  1.284   14.907  1.00 81.25  ? 235 ALA A CB    1 
ATOM   688  N N     . ARG C 3 6  ? -7.075  2.076   16.675  1.00 62.26  ? 236 ARG A N     1 
ATOM   689  C CA    . ARG C 3 6  ? -5.885  1.549   17.309  1.00 64.68  ? 236 ARG A CA    1 
ATOM   690  C C     . ARG C 3 6  ? -6.105  0.064   17.545  1.00 67.14  ? 236 ARG A C     1 
ATOM   691  O O     . ARG C 3 6  ? -7.106  -0.299  18.119  1.00 72.18  ? 236 ARG A O     1 
ATOM   692  C CB    . ARG C 3 6  ? -5.646  2.238   18.651  1.00 65.67  ? 236 ARG A CB    1 
ATOM   693  C CG    . ARG C 3 6  ? -4.512  1.596   19.427  1.00 64.21  ? 236 ARG A CG    1 
ATOM   694  C CD    . ARG C 3 6  ? -3.959  2.636   20.358  1.00 67.00  ? 236 ARG A CD    1 
ATOM   695  N NE    . ARG C 3 6  ? -2.946  2.037   21.231  1.00 61.97  ? 236 ARG A NE    1 
ATOM   696  C CZ    . ARG C 3 6  ? -1.824  2.646   21.551  1.00 64.40  ? 236 ARG A CZ    1 
ATOM   697  N NH1   . ARG C 3 6  ? -1.631  3.888   21.118  1.00 63.25  ? 236 ARG A NH1   1 
ATOM   698  N NH2   . ARG C 3 6  ? -0.901  2.007   22.263  1.00 67.83  ? 236 ARG A NH2   1 
ATOM   699  N N     . THR C 3 7  ? -5.217  -0.797  17.058  1.00 62.09  ? 237 THR A N     1 
ATOM   700  C CA    . THR C 3 7  ? -5.389  -2.226  17.275  1.00 62.66  ? 237 THR A CA    1 
ATOM   701  C C     . THR C 3 7  ? -5.033  -2.518  18.733  1.00 60.55  ? 237 THR A C     1 
ATOM   702  O O     . THR C 3 7  ? -4.054  -1.998  19.262  1.00 62.43  ? 237 THR A O     1 
ATOM   703  C CB    . THR C 3 7  ? -4.516  -3.013  16.283  1.00 67.08  ? 237 THR A CB    1 
ATOM   704  O OG1   . THR C 3 7  ? -5.131  -2.939  15.002  1.00 67.75  ? 237 THR A OG1   1 
ATOM   705  C CG2   . THR C 3 7  ? -4.400  -4.489  16.609  1.00 67.10  ? 237 THR A CG2   1 
ATOM   706  N N     . ALA C 3 8  ? -5.836  -3.346  19.392  1.00 61.36  ? 238 ALA A N     1 
ATOM   707  C CA    . ALA C 3 8  ? -5.440  -3.881  20.687  1.00 69.78  ? 238 ALA A CA    1 
ATOM   708  C C     . ALA C 3 8  ? -5.031  -5.327  20.446  1.00 63.02  ? 238 ALA A C     1 
ATOM   709  O O     . ALA C 3 8  ? -5.879  -6.142  20.119  1.00 63.10  ? 238 ALA A O     1 
ATOM   710  C CB    . ALA C 3 8  ? -6.573  -3.763  21.714  1.00 69.27  ? 238 ALA A CB    1 
ATOM   711  N N     . PHE C 3 9  ? -3.732  -5.611  20.511  1.00 62.80  ? 239 PHE A N     1 
ATOM   712  C CA    . PHE C 3 9  ? -3.255  -6.936  20.151  1.00 62.76  ? 239 PHE A CA    1 
ATOM   713  C C     . PHE C 3 9  ? -3.636  -7.873  21.270  1.00 63.95  ? 239 PHE A C     1 
ATOM   714  O O     . PHE C 3 9  ? -3.755  -7.396  22.380  1.00 63.13  ? 239 PHE A O     1 
ATOM   715  C CB    . PHE C 3 9  ? -1.739  -6.946  20.011  1.00 66.61  ? 239 PHE A CB    1 
ATOM   716  C CG    . PHE C 3 9  ? -1.262  -6.089  18.854  1.00 62.06  ? 239 PHE A CG    1 
ATOM   717  C CD1   . PHE C 3 9  ? -1.561  -6.453  17.544  1.00 65.00  ? 239 PHE A CD1   1 
ATOM   718  C CD2   . PHE C 3 9  ? -0.519  -4.942  19.076  1.00 64.22  ? 239 PHE A CD2   1 
ATOM   719  C CE1   . PHE C 3 9  ? -1.149  -5.672  16.477  1.00 72.11  ? 239 PHE A CE1   1 
ATOM   720  C CE2   . PHE C 3 9  ? -0.066  -4.192  17.995  1.00 75.04  ? 239 PHE A CE2   1 
ATOM   721  C CZ    . PHE C 3 9  ? -0.388  -4.550  16.701  1.00 65.69  ? 239 PHE A CZ    1 
ATOM   722  N N     . SER C 3 10 ? -3.808  -9.165  20.969  1.00 71.57  ? 240 SER A N     1 
ATOM   723  C CA    . SER C 3 10 ? -4.077  -10.157 22.000  1.00 70.25  ? 240 SER A CA    1 
ATOM   724  C C     . SER C 3 10 ? -2.746  -10.507 22.636  1.00 69.24  ? 240 SER A C     1 
ATOM   725  O O     . SER C 3 10 ? -1.706  -10.218 22.057  1.00 65.53  ? 240 SER A O     1 
ATOM   726  C CB    . SER C 3 10 ? -4.765  -11.395 21.475  1.00 64.50  ? 240 SER A CB    1 
ATOM   727  O OG    . SER C 3 10 ? -3.901  -12.158 20.646  1.00 72.43  ? 240 SER A OG    1 
ATOM   728  N N     . ASP C 3 11 ? -2.823  -11.116 23.814  1.00 63.94  ? 241 ASP A N     1 
ATOM   729  C CA    . ASP C 3 11 ? -1.670  -11.610 24.539  1.00 68.35  ? 241 ASP A CA    1 
ATOM   730  C C     . ASP C 3 11 ? -0.880  -12.578 23.671  1.00 66.44  ? 241 ASP A C     1 
ATOM   731  O O     . ASP C 3 11 ? 0.338   -12.657 23.800  1.00 73.34  ? 241 ASP A O     1 
ATOM   732  C CB    . ASP C 3 11 ? -2.082  -12.353 25.806  1.00 74.12  ? 241 ASP A CB    1 
ATOM   733  C CG    . ASP C 3 11 ? -2.491  -11.481 26.982  1.00 77.28  ? 241 ASP A CG    1 
ATOM   734  O OD1   . ASP C 3 11 ? -2.110  -10.304 26.970  1.00 78.27  ? 241 ASP A OD1   1 
ATOM   735  O OD2   . ASP C 3 11 ? -3.176  -11.992 27.903  1.00 83.70  ? 241 ASP A OD2   1 
ATOM   736  N N     . HIS C 3 12 ? -1.585  -13.373 22.858  1.00 66.48  ? 242 HIS A N     1 
ATOM   737  C CA    . HIS C 3 12 ? -0.908  -14.349 22.026  1.00 68.68  ? 242 HIS A CA    1 
ATOM   738  C C     . HIS C 3 12 ? -0.155  -13.599 20.934  1.00 63.40  ? 242 HIS A C     1 
ATOM   739  O O     . HIS C 3 12 ? 0.986   -13.936 20.655  1.00 63.67  ? 242 HIS A O     1 
ATOM   740  C CB    . HIS C 3 12 ? -1.856  -15.393 21.428  1.00 69.88  ? 242 HIS A CB    1 
ATOM   741  C CG    . HIS C 3 12 ? -1.174  -16.401 20.532  1.00 77.58  ? 242 HIS A CG    1 
ATOM   742  N ND1   . HIS C 3 12 ? -0.199  -17.278 20.977  1.00 80.23  ? 242 HIS A ND1   1 
ATOM   743  C CD2   . HIS C 3 12 ? -1.313  -16.653 19.202  1.00 73.71  ? 242 HIS A CD2   1 
ATOM   744  C CE1   . HIS C 3 12 ? 0.202   -18.055 19.968  1.00 75.66  ? 242 HIS A CE1   1 
ATOM   745  N NE2   . HIS C 3 12 ? -0.465  -17.696 18.879  1.00 74.99  ? 242 HIS A NE2   1 
ATOM   746  N N     . GLN C 3 13 ? -0.796  -12.584 20.342  1.00 61.92  ? 243 GLN A N     1 
ATOM   747  C CA    . GLN C 3 13 ? -0.153  -11.778 19.315  1.00 59.37  ? 243 GLN A CA    1 
ATOM   748  C C     . GLN C 3 13 ? 1.088   -11.114 19.885  1.00 64.16  ? 243 GLN A C     1 
ATOM   749  O O     . GLN C 3 13 ? 2.164   -11.297 19.331  1.00 69.90  ? 243 GLN A O     1 
ATOM   750  C CB    . GLN C 3 13 ? -1.142  -10.818 18.673  1.00 55.67  ? 243 GLN A CB    1 
ATOM   751  C CG    . GLN C 3 13 ? -2.144  -11.558 17.795  1.00 57.81  ? 243 GLN A CG    1 
ATOM   752  C CD    . GLN C 3 13 ? -3.403  -10.768 17.533  1.00 57.21  ? 243 GLN A CD    1 
ATOM   753  O OE1   . GLN C 3 13 ? -3.708  -9.783  18.217  1.00 63.60  ? 243 GLN A OE1   1 
ATOM   754  N NE2   . GLN C 3 13 ? -4.114  -11.169 16.490  1.00 54.28  ? 243 GLN A NE2   1 
ATOM   755  N N     . LEU C 3 14 ? 0.950   -10.430 21.029  1.00 66.34  ? 244 LEU A N     1 
ATOM   756  C CA    . LEU C 3 14 ? 2.065   -9.702  21.615  1.00 62.08  ? 244 LEU A CA    1 
ATOM   757  C C     . LEU C 3 14 ? 3.156   -10.702 21.972  1.00 69.23  ? 244 LEU A C     1 
ATOM   758  O O     . LEU C 3 14 ? 4.340   -10.396 21.886  1.00 63.42  ? 244 LEU A O     1 
ATOM   759  C CB    . LEU C 3 14 ? 1.673   -8.900  22.856  1.00 66.15  ? 244 LEU A CB    1 
ATOM   760  C CG    . LEU C 3 14 ? 0.689   -7.742  22.654  1.00 65.04  ? 244 LEU A CG    1 
ATOM   761  C CD1   . LEU C 3 14 ? 0.420   -6.970  23.949  1.00 66.90  ? 244 LEU A CD1   1 
ATOM   762  C CD2   . LEU C 3 14 ? 1.213   -6.787  21.607  1.00 64.82  ? 244 LEU A CD2   1 
ATOM   763  N N     . ASN C 3 15 ? 2.758   -11.891 22.428  1.00 68.08  ? 245 ASN A N     1 
ATOM   764  C CA    . ASN C 3 15 ? 3.755   -12.885 22.791  1.00 75.09  ? 245 ASN A CA    1 
ATOM   765  C C     . ASN C 3 15 ? 4.587   -13.225 21.553  1.00 73.68  ? 245 ASN A C     1 
ATOM   766  O O     . ASN C 3 15 ? 5.808   -13.142 21.602  1.00 77.39  ? 245 ASN A O     1 
ATOM   767  C CB    . ASN C 3 15 ? 3.155   -14.124 23.450  1.00 76.24  ? 245 ASN A CB    1 
ATOM   768  C CG    . ASN C 3 15 ? 4.237   -15.125 23.768  1.00 87.50  ? 245 ASN A CG    1 
ATOM   769  O OD1   . ASN C 3 15 ? 5.182   -14.794 24.492  1.00 100.48 ? 245 ASN A OD1   1 
ATOM   770  N ND2   . ASN C 3 15 ? 4.158   -16.323 23.206  1.00 88.75  ? 245 ASN A ND2   1 
ATOM   771  N N     . GLN C 3 16 ? 3.924   -13.572 20.441  1.00 74.10  ? 246 GLN A N     1 
ATOM   772  C CA    . GLN C 3 16 ? 4.613   -14.096 19.264  1.00 73.03  ? 246 GLN A CA    1 
ATOM   773  C C     . GLN C 3 16 ? 5.401   -12.992 18.549  1.00 68.62  ? 246 GLN A C     1 
ATOM   774  O O     . GLN C 3 16 ? 6.466   -13.254 18.020  1.00 73.44  ? 246 GLN A O     1 
ATOM   775  C CB    . GLN C 3 16 ? 3.621   -14.807 18.339  1.00 73.34  ? 246 GLN A CB    1 
ATOM   776  C CG    . GLN C 3 16 ? 3.066   -16.130 18.874  1.00 67.16  ? 246 GLN A CG    1 
ATOM   777  C CD    . GLN C 3 16 ? 4.083   -17.249 18.981  1.00 77.80  ? 246 GLN A CD    1 
ATOM   778  O OE1   . GLN C 3 16 ? 4.155   -17.983 19.970  1.00 88.15  ? 246 GLN A OE1   1 
ATOM   779  N NE2   . GLN C 3 16 ? 4.870   -17.438 17.941  1.00 82.46  ? 246 GLN A NE2   1 
ATOM   780  N N     . LEU C 3 17 ? 4.919   -11.745 18.571  1.00 64.73  ? 247 LEU A N     1 
ATOM   781  C CA    . LEU C 3 17 ? 5.681   -10.622 18.034  1.00 65.97  ? 247 LEU A CA    1 
ATOM   782  C C     . LEU C 3 17 ? 6.941   -10.330 18.855  1.00 65.25  ? 247 LEU A C     1 
ATOM   783  O O     . LEU C 3 17 ? 7.984   -10.036 18.284  1.00 63.56  ? 247 LEU A O     1 
ATOM   784  C CB    . LEU C 3 17 ? 4.813   -9.372  17.929  1.00 63.76  ? 247 LEU A CB    1 
ATOM   785  C CG    . LEU C 3 17 ? 3.589   -9.505  17.027  1.00 65.03  ? 247 LEU A CG    1 
ATOM   786  C CD1   . LEU C 3 17 ? 2.587   -8.416  17.396  1.00 65.97  ? 247 LEU A CD1   1 
ATOM   787  C CD2   . LEU C 3 17 ? 3.973   -9.415  15.552  1.00 64.34  ? 247 LEU A CD2   1 
ATOM   788  N N     . GLU C 3 18 ? 6.856   -10.377 20.190  1.00 70.20  ? 248 GLU A N     1 
ATOM   789  C CA    . GLU C 3 18 ? 8.036   -10.252 21.037  1.00 72.97  ? 248 GLU A CA    1 
ATOM   790  C C     . GLU C 3 18 ? 9.030   -11.365 20.729  1.00 76.11  ? 248 GLU A C     1 
ATOM   791  O O     . GLU C 3 18 ? 10.238  -11.124 20.687  1.00 75.60  ? 248 GLU A O     1 
ATOM   792  C CB    . GLU C 3 18 ? 7.780   -10.370 22.539  1.00 83.01  ? 248 GLU A CB    1 
ATOM   793  C CG    . GLU C 3 18 ? 7.226   -9.103  23.179  1.00 89.82  ? 248 GLU A CG    1 
ATOM   794  C CD    . GLU C 3 18 ? 8.020   -7.869  22.803  1.00 93.06  ? 248 GLU A CD    1 
ATOM   795  O OE1   . GLU C 3 18 ? 7.376   -6.800  22.681  1.00 89.66  ? 248 GLU A OE1   1 
ATOM   796  O OE2   . GLU C 3 18 ? 9.259   -7.991  22.610  1.00 94.72  ? 248 GLU A OE2   1 
ATOM   797  N N     . ARG C 3 19 ? 8.519   -12.580 20.516  1.00 75.61  ? 249 ARG A N     1 
ATOM   798  C CA    . ARG C 3 19 ? 9.378   -13.709 20.203  1.00 75.25  ? 249 ARG A CA    1 
ATOM   799  C C     . ARG C 3 19 ? 10.111  -13.452 18.898  1.00 70.35  ? 249 ARG A C     1 
ATOM   800  O O     . ARG C 3 19 ? 11.334  -13.472 18.854  1.00 75.28  ? 249 ARG A O     1 
ATOM   801  C CB    . ARG C 3 19 ? 8.560   -14.995 20.153  1.00 81.88  ? 249 ARG A CB    1 
ATOM   802  C CG    . ARG C 3 19 ? 8.110   -15.328 21.566  1.00 90.43  ? 249 ARG A CG    1 
ATOM   803  C CD    . ARG C 3 19 ? 7.352   -16.631 21.701  1.00 93.78  ? 249 ARG A CD    1 
ATOM   804  N NE    . ARG C 3 19 ? 8.214   -17.724 22.154  1.00 94.29  ? 249 ARG A NE    1 
ATOM   805  C CZ    . ARG C 3 19 ? 7.747   -18.779 22.792  1.00 93.72  ? 249 ARG A CZ    1 
ATOM   806  N NH1   . ARG C 3 19 ? 6.454   -18.893 23.015  1.00 98.96  ? 249 ARG A NH1   1 
ATOM   807  N NH2   . ARG C 3 19 ? 8.572   -19.702 23.221  1.00 89.37  ? 249 ARG A NH2   1 
ATOM   808  N N     . SER C 3 20 ? 9.357   -13.146 17.844  1.00 78.50  ? 250 SER A N     1 
ATOM   809  C CA    . SER C 3 20 ? 9.954   -12.894 16.543  1.00 70.09  ? 250 SER A CA    1 
ATOM   810  C C     . SER C 3 20 ? 11.026  -11.822 16.694  1.00 69.82  ? 250 SER A C     1 
ATOM   811  O O     . SER C 3 20 ? 12.151  -11.986 16.237  1.00 74.78  ? 250 SER A O     1 
ATOM   812  C CB    . SER C 3 20 ? 8.909   -12.543 15.537  1.00 63.10  ? 250 SER A CB    1 
ATOM   813  O OG    . SER C 3 20 ? 9.461   -11.884 14.404  1.00 75.90  ? 250 SER A OG    1 
ATOM   814  N N     . PHE C 3 21 ? 10.700  -10.768 17.437  1.00 70.39  ? 251 PHE A N     1 
ATOM   815  C CA    . PHE C 3 21 ? 11.608  -9.643  17.600  1.00 72.11  ? 251 PHE A CA    1 
ATOM   816  C C     . PHE C 3 21 ? 12.903  -10.087 18.252  1.00 74.74  ? 251 PHE A C     1 
ATOM   817  O O     . PHE C 3 21 ? 13.961  -9.556  17.961  1.00 80.77  ? 251 PHE A O     1 
ATOM   818  C CB    . PHE C 3 21 ? 11.004  -8.556  18.491  1.00 69.92  ? 251 PHE A CB    1 
ATOM   819  C CG    . PHE C 3 21 ? 11.844  -7.288  18.507  1.00 67.37  ? 251 PHE A CG    1 
ATOM   820  C CD1   . PHE C 3 21 ? 11.991  -6.536  17.352  1.00 60.99  ? 251 PHE A CD1   1 
ATOM   821  C CD2   . PHE C 3 21 ? 12.507  -6.880  19.653  1.00 73.45  ? 251 PHE A CD2   1 
ATOM   822  C CE1   . PHE C 3 21 ? 12.763  -5.390  17.345  1.00 68.16  ? 251 PHE A CE1   1 
ATOM   823  C CE2   . PHE C 3 21 ? 13.290  -5.739  19.637  1.00 77.80  ? 251 PHE A CE2   1 
ATOM   824  C CZ    . PHE C 3 21 ? 13.384  -4.977  18.492  1.00 71.57  ? 251 PHE A CZ    1 
ATOM   825  N N     . GLU C 3 22 ? 12.762  -11.006 19.205  1.00 88.37  ? 252 GLU A N     1 
ATOM   826  C CA    . GLU C 3 22 ? 13.876  -11.610 19.902  1.00 89.00  ? 252 GLU A CA    1 
ATOM   827  C C     . GLU C 3 22 ? 14.696  -12.403 18.890  1.00 89.74  ? 252 GLU A C     1 
ATOM   828  O O     . GLU C 3 22 ? 15.924  -12.316 18.900  1.00 100.96 ? 252 GLU A O     1 
ATOM   829  C CB    . GLU C 3 22 ? 13.317  -12.441 21.065  1.00 96.56  ? 252 GLU A CB    1 
ATOM   830  C CG    . GLU C 3 22 ? 14.386  -13.155 21.885  1.00 106.66 ? 252 GLU A CG    1 
ATOM   831  C CD    . GLU C 3 22 ? 15.426  -12.243 22.525  1.00 109.98 ? 252 GLU A CD    1 
ATOM   832  O OE1   . GLU C 3 22 ? 16.453  -12.755 23.017  1.00 107.78 ? 252 GLU A OE1   1 
ATOM   833  O OE2   . GLU C 3 22 ? 15.207  -11.017 22.556  1.00 110.03 ? 252 GLU A OE2   1 
ATOM   834  N N     . ARG C 3 23 ? 14.013  -13.177 18.033  1.00 81.60  ? 253 ARG A N     1 
ATOM   835  C CA    . ARG C 3 23 ? 14.690  -13.964 17.009  1.00 83.69  ? 253 ARG A CA    1 
ATOM   836  C C     . ARG C 3 23 ? 15.347  -13.034 15.988  1.00 79.40  ? 253 ARG A C     1 
ATOM   837  O O     . ARG C 3 23 ? 16.463  -13.276 15.540  1.00 74.20  ? 253 ARG A O     1 
ATOM   838  C CB    . ARG C 3 23 ? 13.773  -14.932 16.249  1.00 81.66  ? 253 ARG A CB    1 
ATOM   839  C CG    . ARG C 3 23 ? 13.435  -16.209 17.005  1.00 89.16  ? 253 ARG A CG    1 
ATOM   840  C CD    . ARG C 3 23 ? 12.679  -17.239 16.152  1.00 93.73  ? 253 ARG A CD    1 
ATOM   841  N NE    . ARG C 3 23 ? 11.505  -16.744 15.418  1.00 96.39  ? 253 ARG A NE    1 
ATOM   842  C CZ    . ARG C 3 23 ? 10.300  -16.467 15.923  1.00 96.22  ? 253 ARG A CZ    1 
ATOM   843  N NH1   . ARG C 3 23 ? 10.038  -16.682 17.200  1.00 98.93  ? 253 ARG A NH1   1 
ATOM   844  N NH2   . ARG C 3 23 ? 9.359   -15.972 15.139  1.00 88.03  ? 253 ARG A NH2   1 
ATOM   845  N N     . GLN C 3 24 ? 14.651  -11.954 15.629  1.00 75.63  ? 254 GLN A N     1 
ATOM   846  C CA    . GLN C 3 24 ? 15.060  -11.147 14.496  1.00 70.61  ? 254 GLN A CA    1 
ATOM   847  C C     . GLN C 3 24 ? 14.543  -9.713  14.607  1.00 68.28  ? 254 GLN A C     1 
ATOM   848  O O     . GLN C 3 24 ? 13.335  -9.484  14.663  1.00 65.31  ? 254 GLN A O     1 
ATOM   849  C CB    . GLN C 3 24 ? 14.382  -11.787 13.294  1.00 70.83  ? 254 GLN A CB    1 
ATOM   850  C CG    . GLN C 3 24 ? 14.941  -13.130 12.843  1.00 73.56  ? 254 GLN A CG    1 
ATOM   851  C CD    . GLN C 3 24 ? 14.286  -13.492 11.532  1.00 78.19  ? 254 GLN A CD    1 
ATOM   852  O OE1   . GLN C 3 24 ? 13.407  -14.357 11.466  1.00 79.57  ? 254 GLN A OE1   1 
ATOM   853  N NE2   . GLN C 3 24 ? 14.608  -12.716 10.501  1.00 79.35  ? 254 GLN A NE2   1 
ATOM   854  N N     . LYS C 3 25 ? 15.473  -8.762  14.560  1.00 66.27  ? 255 LYS A N     1 
ATOM   855  C CA    . LYS C 3 25 ? 15.172  -7.351  14.708  1.00 74.64  ? 255 LYS A CA    1 
ATOM   856  C C     . LYS C 3 25 ? 14.603  -6.803  13.407  1.00 69.44  ? 255 LYS A C     1 
ATOM   857  O O     . LYS C 3 25 ? 13.848  -5.828  13.402  1.00 62.81  ? 255 LYS A O     1 
ATOM   858  C CB    . LYS C 3 25 ? 16.457  -6.649  15.149  1.00 75.73  ? 255 LYS A CB    1 
ATOM   859  C CG    . LYS C 3 25 ? 16.942  -7.125  16.513  1.00 83.44  ? 255 LYS A CG    1 
ATOM   860  C CD    . LYS C 3 25 ? 16.608  -6.228  17.695  1.00 83.94  ? 255 LYS A CD    1 
ATOM   861  C CE    . LYS C 3 25 ? 17.301  -6.701  18.942  1.00 93.27  ? 255 LYS A CE    1 
ATOM   862  N NZ    . LYS C 3 25 ? 16.785  -8.013  19.346  1.00 93.30  ? 255 LYS A NZ    1 
ATOM   863  N N     . TYR C 3 26 ? 14.983  -7.453  12.312  1.00 66.04  ? 256 TYR A N     1 
ATOM   864  C CA    . TYR C 3 26 ? 14.427  -7.134  11.014  1.00 62.47  ? 256 TYR A CA    1 
ATOM   865  C C     . TYR C 3 26 ? 13.932  -8.442  10.419  1.00 59.03  ? 256 TYR A C     1 
ATOM   866  O O     . TYR C 3 26 ? 14.448  -9.500  10.784  1.00 57.65  ? 256 TYR A O     1 
ATOM   867  C CB    . TYR C 3 26 ? 15.468  -6.410  10.162  1.00 64.95  ? 256 TYR A CB    1 
ATOM   868  C CG    . TYR C 3 26 ? 15.956  -5.075  10.719  1.00 66.76  ? 256 TYR A CG    1 
ATOM   869  C CD1   . TYR C 3 26 ? 16.903  -4.983  11.745  1.00 66.33  ? 256 TYR A CD1   1 
ATOM   870  C CD2   . TYR C 3 26 ? 15.445  -3.891  10.210  1.00 71.32  ? 256 TYR A CD2   1 
ATOM   871  C CE1   . TYR C 3 26 ? 17.323  -3.746  12.229  1.00 64.87  ? 256 TYR A CE1   1 
ATOM   872  C CE2   . TYR C 3 26 ? 15.858  -2.653  10.683  1.00 71.85  ? 256 TYR A CE2   1 
ATOM   873  C CZ    . TYR C 3 26 ? 16.802  -2.581  11.687  1.00 66.31  ? 256 TYR A CZ    1 
ATOM   874  O OH    . TYR C 3 26 ? 17.098  -1.310  12.070  1.00 67.64  ? 256 TYR A OH    1 
ATOM   875  N N     . LEU C 3 27 ? 12.856  -8.312  9.625   1.00 53.29  ? 257 LEU A N     1 
ATOM   876  C CA    . LEU C 3 27 ? 12.195  -9.379  8.906   1.00 58.58  ? 257 LEU A CA    1 
ATOM   877  C C     . LEU C 3 27 ? 12.276  -9.116  7.407   1.00 62.00  ? 257 LEU A C     1 
ATOM   878  O O     . LEU C 3 27 ? 12.104  -7.983  6.965   1.00 54.78  ? 257 LEU A O     1 
ATOM   879  C CB    . LEU C 3 27 ? 10.713  -9.458  9.279   1.00 59.83  ? 257 LEU A CB    1 
ATOM   880  C CG    . LEU C 3 27 ? 10.343  -10.088 10.624  1.00 58.69  ? 257 LEU A CG    1 
ATOM   881  C CD1   . LEU C 3 27 ? 8.822   -10.146 10.609  1.00 64.74  ? 257 LEU A CD1   1 
ATOM   882  C CD2   . LEU C 3 27 ? 10.892  -11.465 10.986  1.00 52.79  ? 257 LEU A CD2   1 
ATOM   883  N N     . SER C 3 28 ? 12.413  -10.205 6.651   1.00 67.71  ? 258 SER A N     1 
ATOM   884  C CA    . SER C 3 28 ? 12.183  -10.206 5.218   1.00 68.58  ? 258 SER A CA    1 
ATOM   885  C C     . SER C 3 28 ? 10.704  -9.953  4.966   1.00 67.37  ? 258 SER A C     1 
ATOM   886  O O     . SER C 3 28 ? 9.889   -10.086 5.876   1.00 72.09  ? 258 SER A O     1 
ATOM   887  C CB    . SER C 3 28 ? 12.634  -11.535 4.568   1.00 66.22  ? 258 SER A CB    1 
ATOM   888  O OG    . SER C 3 28 ? 12.132  -12.665 5.275   1.00 64.47  ? 258 SER A OG    1 
ATOM   889  N N     . VAL C 3 29 ? 10.387  -9.633  3.708   1.00 64.29  ? 259 VAL A N     1 
ATOM   890  C CA    . VAL C 3 29 ? 9.024   -9.578  3.226   1.00 64.38  ? 259 VAL A CA    1 
ATOM   891  C C     . VAL C 3 29 ? 8.385   -10.907 3.586   1.00 58.26  ? 259 VAL A C     1 
ATOM   892  O O     . VAL C 3 29 ? 7.279   -10.959 4.107   1.00 56.86  ? 259 VAL A O     1 
ATOM   893  C CB    . VAL C 3 29 ? 8.915   -9.323  1.709   1.00 76.97  ? 259 VAL A CB    1 
ATOM   894  C CG1   . VAL C 3 29 ? 7.464   -9.261  1.228   1.00 76.80  ? 259 VAL A CG1   1 
ATOM   895  C CG2   . VAL C 3 29 ? 9.664   -8.067  1.304   1.00 76.79  ? 259 VAL A CG2   1 
ATOM   896  N N     . GLN C 3 30 ? 9.077   -11.999 3.297   1.00 56.81  ? 260 GLN A N     1 
ATOM   897  C CA    . GLN C 3 30 ? 8.436   -13.297 3.449   1.00 64.98  ? 260 GLN A CA    1 
ATOM   898  C C     . GLN C 3 30 ? 8.118   -13.588 4.928   1.00 60.13  ? 260 GLN A C     1 
ATOM   899  O O     . GLN C 3 30 ? 6.988   -13.933 5.244   1.00 68.15  ? 260 GLN A O     1 
ATOM   900  C CB    . GLN C 3 30 ? 9.229   -14.401 2.744   1.00 65.13  ? 260 GLN A CB    1 
ATOM   901  C CG    . GLN C 3 30 ? 8.454   -15.705 2.551   1.00 69.22  ? 260 GLN A CG    1 
ATOM   902  C CD    . GLN C 3 30 ? 7.044   -15.464 2.046   1.00 82.83  ? 260 GLN A CD    1 
ATOM   903  O OE1   . GLN C 3 30 ? 6.804   -14.563 1.227   1.00 83.38  ? 260 GLN A OE1   1 
ATOM   904  N NE2   . GLN C 3 30 ? 6.082   -16.197 2.598   1.00 79.24  ? 260 GLN A NE2   1 
ATOM   905  N N     . ASP C 3 31 ? 9.095   -13.482 5.834   1.00 58.80  ? 261 ASP A N     1 
ATOM   906  C CA    . ASP C 3 31 ? 8.842   -13.749 7.246   1.00 65.36  ? 261 ASP A CA    1 
ATOM   907  C C     . ASP C 3 31 ? 7.727   -12.842 7.779   1.00 62.66  ? 261 ASP A C     1 
ATOM   908  O O     . ASP C 3 31 ? 6.902   -13.254 8.608   1.00 55.41  ? 261 ASP A O     1 
ATOM   909  C CB    . ASP C 3 31 ? 10.120  -13.640 8.066   1.00 60.00  ? 261 ASP A CB    1 
ATOM   910  C CG    . ASP C 3 31 ? 11.104  -14.755 7.766   1.00 68.36  ? 261 ASP A CG    1 
ATOM   911  O OD1   . ASP C 3 31 ? 10.665  -15.731 7.146   1.00 72.75  ? 261 ASP A OD1   1 
ATOM   912  O OD2   . ASP C 3 31 ? 12.274  -14.648 8.173   1.00 68.92  ? 261 ASP A OD2   1 
ATOM   913  N N     . ARG C 3 32 ? 7.715   -11.600 7.310   1.00 51.47  ? 262 ARG A N     1 
ATOM   914  C CA    . ARG C 3 32 ? 6.737   -10.665 7.830   1.00 58.21  ? 262 ARG A CA    1 
ATOM   915  C C     . ARG C 3 32 ? 5.328   -11.146 7.501   1.00 59.52  ? 262 ARG A C     1 
ATOM   916  O O     . ARG C 3 32 ? 4.472   -11.137 8.392   1.00 54.10  ? 262 ARG A O     1 
ATOM   917  C CB    . ARG C 3 32 ? 6.943   -9.238  7.331   1.00 61.52  ? 262 ARG A CB    1 
ATOM   918  C CG    . ARG C 3 32 ? 5.821   -8.339  7.822   1.00 65.39  ? 262 ARG A CG    1 
ATOM   919  C CD    . ARG C 3 32 ? 6.169   -6.902  7.561   1.00 72.38  ? 262 ARG A CD    1 
ATOM   920  N NE    . ARG C 3 32 ? 6.118   -6.689  6.116   1.00 74.08  ? 262 ARG A NE    1 
ATOM   921  C CZ    . ARG C 3 32 ? 7.164   -6.370  5.396   1.00 88.31  ? 262 ARG A CZ    1 
ATOM   922  N NH1   . ARG C 3 32 ? 7.004   -6.137  4.113   1.00 86.49  ? 262 ARG A NH1   1 
ATOM   923  N NH2   . ARG C 3 32 ? 8.355   -6.263  5.962   1.00 92.19  ? 262 ARG A NH2   1 
ATOM   924  N N     . MET C 3 33 ? 5.134   -11.565 6.241   1.00 54.58  ? 263 MET A N     1 
ATOM   925  C CA    . MET C 3 33 ? 3.835   -11.907 5.690   1.00 61.00  ? 263 MET A CA    1 
ATOM   926  C C     . MET C 3 33 ? 3.335   -13.190 6.337   1.00 67.25  ? 263 MET A C     1 
ATOM   927  O O     . MET C 3 33 ? 2.132   -13.332 6.560   1.00 66.37  ? 263 MET A O     1 
ATOM   928  C CB    . MET C 3 33 ? 3.881   -12.198 4.183   1.00 65.13  ? 263 MET A CB    1 
ATOM   929  C CG    . MET C 3 33 ? 3.890   -10.968 3.279   1.00 76.66  ? 263 MET A CG    1 
ATOM   930  S SD    . MET C 3 33 ? 3.829   -11.381 1.520   1.00 86.59  ? 263 MET A SD    1 
ATOM   931  C CE    . MET C 3 33 ? 3.800   -9.754  0.754   1.00 82.71  ? 263 MET A CE    1 
ATOM   932  N N     . ASP C 3 34 ? 4.274   -14.122 6.557   1.00 60.59  ? 264 ASP A N     1 
ATOM   933  C CA    . ASP C 3 34 ? 3.989   -15.365 7.250   1.00 58.94  ? 264 ASP A CA    1 
ATOM   934  C C     . ASP C 3 34 ? 3.651   -15.112 8.713   1.00 62.17  ? 264 ASP A C     1 
ATOM   935  O O     . ASP C 3 34 ? 2.740   -15.751 9.212   1.00 62.00  ? 264 ASP A O     1 
ATOM   936  C CB    . ASP C 3 34 ? 5.166   -16.313 7.348   1.00 65.13  ? 264 ASP A CB    1 
ATOM   937  C CG    . ASP C 3 34 ? 5.597   -16.969 6.051   1.00 69.48  ? 264 ASP A CG    1 
ATOM   938  O OD1   . ASP C 3 34 ? 5.058   -16.565 4.979   1.00 62.91  ? 264 ASP A OD1   1 
ATOM   939  O OD2   . ASP C 3 34 ? 6.473   -17.864 6.150   1.00 71.25  ? 264 ASP A OD2   1 
ATOM   940  N N     . LEU C 3 35 ? 4.391   -14.232 9.403   1.00 53.90  ? 265 LEU A N     1 
ATOM   941  C CA    . LEU C 3 35 ? 4.050   -13.934 10.793  1.00 59.34  ? 265 LEU A CA    1 
ATOM   942  C C     . LEU C 3 35 ? 2.680   -13.245 10.847  1.00 62.58  ? 265 LEU A C     1 
ATOM   943  O O     . LEU C 3 35 ? 1.875   -13.522 11.724  1.00 57.01  ? 265 LEU A O     1 
ATOM   944  C CB    . LEU C 3 35 ? 5.149   -13.120 11.469  1.00 50.84  ? 265 LEU A CB    1 
ATOM   945  C CG    . LEU C 3 35 ? 4.955   -12.812 12.950  1.00 57.76  ? 265 LEU A CG    1 
ATOM   946  C CD1   . LEU C 3 35 ? 5.104   -14.017 13.846  1.00 55.70  ? 265 LEU A CD1   1 
ATOM   947  C CD2   . LEU C 3 35 ? 5.983   -11.762 13.289  1.00 57.54  ? 265 LEU A CD2   1 
ATOM   948  N N     . ALA C 3 36 ? 2.373   -12.418 9.839   1.00 62.25  ? 266 ALA A N     1 
ATOM   949  C CA    . ALA C 3 36 ? 1.070   -11.779 9.753   1.00 64.62  ? 266 ALA A CA    1 
ATOM   950  C C     . ALA C 3 36 ? -0.023  -12.832 9.654   1.00 65.33  ? 266 ALA A C     1 
ATOM   951  O O     . ALA C 3 36 ? -0.984  -12.788 10.400  1.00 63.15  ? 266 ALA A O     1 
ATOM   952  C CB    . ALA C 3 36 ? 1.001   -10.825 8.564   1.00 65.85  ? 266 ALA A CB    1 
ATOM   953  N N     . ALA C 3 37 ? 0.140   -13.765 8.715   1.00 56.09  ? 267 ALA A N     1 
ATOM   954  C CA    . ALA C 3 37 ? -0.891  -14.742 8.450   1.00 62.51  ? 267 ALA A CA    1 
ATOM   955  C C     . ALA C 3 37 ? -1.130  -15.598 9.684   1.00 59.14  ? 267 ALA A C     1 
ATOM   956  O O     . ALA C 3 37 ? -2.262  -15.975 9.918   1.00 72.38  ? 267 ALA A O     1 
ATOM   957  C CB    . ALA C 3 37 ? -0.516  -15.598 7.252   1.00 64.34  ? 267 ALA A CB    1 
ATOM   958  N N     . ALA C 3 38 ? -0.065  -15.899 10.438  1.00 54.13  ? 268 ALA A N     1 
ATOM   959  C CA    . ALA C 3 38 ? -0.123  -16.857 11.537  1.00 61.99  ? 268 ALA A CA    1 
ATOM   960  C C     . ALA C 3 38 ? -0.891  -16.281 12.737  1.00 55.23  ? 268 ALA A C     1 
ATOM   961  O O     . ALA C 3 38 ? -1.358  -17.036 13.576  1.00 59.02  ? 268 ALA A O     1 
ATOM   962  C CB    . ALA C 3 38 ? 1.279   -17.309 11.959  1.00 53.93  ? 268 ALA A CB    1 
ATOM   963  N N     . LEU C 3 39 ? -0.962  -14.959 12.812  1.00 51.81  ? 269 LEU A N     1 
ATOM   964  C CA    . LEU C 3 39 ? -1.544  -14.212 13.917  1.00 53.93  ? 269 LEU A CA    1 
ATOM   965  C C     . LEU C 3 39 ? -2.837  -13.512 13.507  1.00 56.67  ? 269 LEU A C     1 
ATOM   966  O O     . LEU C 3 39 ? -3.442  -12.829 14.327  1.00 69.25  ? 269 LEU A O     1 
ATOM   967  C CB    . LEU C 3 39 ? -0.532  -13.140 14.322  1.00 49.70  ? 269 LEU A CB    1 
ATOM   968  C CG    . LEU C 3 39 ? 0.817   -13.630 14.851  1.00 51.74  ? 269 LEU A CG    1 
ATOM   969  C CD1   . LEU C 3 39 ? 1.545   -12.397 15.281  1.00 56.63  ? 269 LEU A CD1   1 
ATOM   970  C CD2   . LEU C 3 39 ? 0.812   -14.580 16.015  1.00 54.74  ? 269 LEU A CD2   1 
ATOM   971  N N     . ASN C 3 40 ? -3.231  -13.640 12.235  1.00 51.87  ? 270 ASN A N     1 
ATOM   972  C CA    . ASN C 3 40 ? -4.374  -12.945 11.680  1.00 54.39  ? 270 ASN A CA    1 
ATOM   973  C C     . ASN C 3 40 ? -4.235  -11.433 11.824  1.00 59.27  ? 270 ASN A C     1 
ATOM   974  O O     . ASN C 3 40 ? -5.224  -10.756 12.139  1.00 66.83  ? 270 ASN A O     1 
ATOM   975  C CB    . ASN C 3 40 ? -5.670  -13.403 12.326  1.00 60.53  ? 270 ASN A CB    1 
ATOM   976  C CG    . ASN C 3 40 ? -6.268  -14.568 11.586  1.00 74.75  ? 270 ASN A CG    1 
ATOM   977  O OD1   . ASN C 3 40 ? -6.600  -14.441 10.398  1.00 79.40  ? 270 ASN A OD1   1 
ATOM   978  N ND2   . ASN C 3 40 ? -6.408  -15.695 12.271  1.00 85.58  ? 270 ASN A ND2   1 
ATOM   979  N N     . LEU C 3 41 ? -3.024  -10.934 11.580  1.00 53.35  ? 271 LEU A N     1 
ATOM   980  C CA    . LEU C 3 41 ? -2.765  -9.514  11.351  1.00 54.31  ? 271 LEU A CA    1 
ATOM   981  C C     . LEU C 3 41 ? -2.421  -9.256  9.885   1.00 62.26  ? 271 LEU A C     1 
ATOM   982  O O     . LEU C 3 41 ? -1.984  -10.170 9.165   1.00 58.21  ? 271 LEU A O     1 
ATOM   983  C CB    . LEU C 3 41 ? -1.599  -9.127  12.255  1.00 52.00  ? 271 LEU A CB    1 
ATOM   984  C CG    . LEU C 3 41 ? -1.813  -9.403  13.748  1.00 55.49  ? 271 LEU A CG    1 
ATOM   985  C CD1   . LEU C 3 41 ? -0.636  -8.995  14.569  1.00 55.67  ? 271 LEU A CD1   1 
ATOM   986  C CD2   . LEU C 3 41 ? -3.077  -8.691  14.211  1.00 59.10  ? 271 LEU A CD2   1 
ATOM   987  N N     . THR C 3 42 ? -2.626  -7.999  9.448   1.00 61.36  ? 272 THR A N     1 
ATOM   988  C CA    . THR C 3 42 ? -2.163  -7.547  8.137   1.00 58.99  ? 272 THR A CA    1 
ATOM   989  C C     . THR C 3 42 ? -0.643  -7.374  8.190   1.00 56.52  ? 272 THR A C     1 
ATOM   990  O O     . THR C 3 42 ? -0.052  -7.168  9.256   1.00 62.50  ? 272 THR A O     1 
ATOM   991  C CB    . THR C 3 42 ? -2.810  -6.229  7.701   1.00 56.03  ? 272 THR A CB    1 
ATOM   992  O OG1   . THR C 3 42 ? -2.344  -5.272  8.647   1.00 57.66  ? 272 THR A OG1   1 
ATOM   993  C CG2   . THR C 3 42 ? -4.327  -6.251  7.718   1.00 59.67  ? 272 THR A CG2   1 
ATOM   994  N N     . ASP C 3 43 ? -0.023  -7.428  7.012   1.00 54.93  ? 273 ASP A N     1 
ATOM   995  C CA    . ASP C 3 43 ? 1.369   -7.060  6.844   1.00 50.10  ? 273 ASP A CA    1 
ATOM   996  C C     . ASP C 3 43 ? 1.671   -5.732  7.522   1.00 44.03  ? 273 ASP A C     1 
ATOM   997  O O     . ASP C 3 43 ? 2.689   -5.618  8.195   1.00 46.93  ? 273 ASP A O     1 
ATOM   998  C CB    . ASP C 3 43 ? 1.736   -6.899  5.377   1.00 63.00  ? 273 ASP A CB    1 
ATOM   999  C CG    . ASP C 3 43 ? 2.670   -7.974  4.852   1.00 87.62  ? 273 ASP A CG    1 
ATOM   1000 O OD1   . ASP C 3 43 ? 2.218   -9.144  4.792   1.00 90.11  ? 273 ASP A OD1   1 
ATOM   1001 O OD2   . ASP C 3 43 ? 3.842   -7.630  4.541   1.00 100.91 ? 273 ASP A OD2   1 
ATOM   1002 N N     . THR C 3 44 ? 0.833   -4.716  7.282   1.00 46.90  ? 274 THR A N     1 
ATOM   1003 C CA    . THR C 3 44 ? 1.146   -3.392  7.781   1.00 52.34  ? 274 THR A CA    1 
ATOM   1004 C C     . THR C 3 44 ? 1.213   -3.416  9.304   1.00 52.45  ? 274 THR A C     1 
ATOM   1005 O O     . THR C 3 44 ? 2.101   -2.806  9.921   1.00 57.68  ? 274 THR A O     1 
ATOM   1006 C CB    . THR C 3 44 ? 0.088   -2.393  7.347   1.00 54.16  ? 274 THR A CB    1 
ATOM   1007 O OG1   . THR C 3 44 ? 0.109   -2.489  5.944   1.00 49.26  ? 274 THR A OG1   1 
ATOM   1008 C CG2   . THR C 3 44 ? 0.435   -0.982  7.774   1.00 60.49  ? 274 THR A CG2   1 
ATOM   1009 N N     . GLN C 3 45 ? 0.231   -4.076  9.918   1.00 50.46  ? 275 GLN A N     1 
ATOM   1010 C CA    . GLN C 3 45 ? 0.189   -4.086  11.372  1.00 48.73  ? 275 GLN A CA    1 
ATOM   1011 C C     . GLN C 3 45 ? 1.501   -4.636  11.888  1.00 48.22  ? 275 GLN A C     1 
ATOM   1012 O O     . GLN C 3 45 ? 2.096   -4.120  12.851  1.00 53.54  ? 275 GLN A O     1 
ATOM   1013 C CB    . GLN C 3 45 ? -0.947  -4.950  11.922  1.00 49.79  ? 275 GLN A CB    1 
ATOM   1014 C CG    . GLN C 3 45 ? -2.315  -4.315  11.706  1.00 56.53  ? 275 GLN A CG    1 
ATOM   1015 C CD    . GLN C 3 45 ? -3.450  -5.270  11.973  1.00 55.44  ? 275 GLN A CD    1 
ATOM   1016 O OE1   . GLN C 3 45 ? -3.451  -6.397  11.473  1.00 54.71  ? 275 GLN A OE1   1 
ATOM   1017 N NE2   . GLN C 3 45 ? -4.362  -4.868  12.848  1.00 63.48  ? 275 GLN A NE2   1 
ATOM   1018 N N     . VAL C 3 46 ? 1.924   -5.737  11.246  1.00 51.56  ? 276 VAL A N     1 
ATOM   1019 C CA    . VAL C 3 46 ? 3.151   -6.359  11.685  1.00 50.23  ? 276 VAL A CA    1 
ATOM   1020 C C     . VAL C 3 46 ? 4.334   -5.436  11.373  1.00 50.35  ? 276 VAL A C     1 
ATOM   1021 O O     . VAL C 3 46 ? 5.255   -5.353  12.165  1.00 53.26  ? 276 VAL A O     1 
ATOM   1022 C CB    . VAL C 3 46 ? 3.394   -7.762  11.142  1.00 46.60  ? 276 VAL A CB    1 
ATOM   1023 C CG1   . VAL C 3 46 ? 4.698   -8.270  11.700  1.00 47.22  ? 276 VAL A CG1   1 
ATOM   1024 C CG2   . VAL C 3 46 ? 2.266   -8.699  11.504  1.00 48.98  ? 276 VAL A CG2   1 
ATOM   1025 N N     . LYS C 3 47 ? 4.319   -4.718  10.244  1.00 54.80  ? 277 LYS A N     1 
ATOM   1026 C CA    . LYS C 3 47 ? 5.450   -3.856  9.936   1.00 52.47  ? 277 LYS A CA    1 
ATOM   1027 C C     . LYS C 3 47 ? 5.493   -2.705  10.950  1.00 51.93  ? 277 LYS A C     1 
ATOM   1028 O O     . LYS C 3 47 ? 6.561   -2.340  11.429  1.00 51.01  ? 277 LYS A O     1 
ATOM   1029 C CB    . LYS C 3 47 ? 5.311   -3.339  8.500   1.00 52.42  ? 277 LYS A CB    1 
ATOM   1030 C CG    . LYS C 3 47 ? 6.493   -2.567  7.969   1.00 56.00  ? 277 LYS A CG    1 
ATOM   1031 C CD    . LYS C 3 47 ? 6.245   -1.571  6.829   1.00 64.19  ? 277 LYS A CD    1 
ATOM   1032 C CE    . LYS C 3 47 ? 5.381   -2.036  5.699   1.00 76.23  ? 277 LYS A CE    1 
ATOM   1033 N NZ    . LYS C 3 47 ? 4.049   -1.420  5.755   1.00 86.05  ? 277 LYS A NZ    1 
ATOM   1034 N N     . THR C 3 48 ? 4.332   -2.092  11.237  1.00 52.24  ? 278 THR A N     1 
ATOM   1035 C CA    . THR C 3 48 ? 4.296   -0.946  12.136  1.00 49.36  ? 278 THR A CA    1 
ATOM   1036 C C     . THR C 3 48 ? 4.672   -1.376  13.552  1.00 57.39  ? 278 THR A C     1 
ATOM   1037 O O     . THR C 3 48 ? 5.352   -0.612  14.255  1.00 54.64  ? 278 THR A O     1 
ATOM   1038 C CB    . THR C 3 48 ? 2.912   -0.338  12.166  1.00 57.37  ? 278 THR A CB    1 
ATOM   1039 O OG1   . THR C 3 48 ? 2.617   -0.127  10.804  1.00 45.53  ? 278 THR A OG1   1 
ATOM   1040 C CG2   . THR C 3 48 ? 2.853   0.953   12.978  1.00 59.71  ? 278 THR A CG2   1 
ATOM   1041 N N     . TRP C 3 49 ? 4.238   -2.591  13.947  1.00 47.35  ? 279 TRP A N     1 
ATOM   1042 C CA    . TRP C 3 49 ? 4.657   -3.138  15.224  1.00 49.04  ? 279 TRP A CA    1 
ATOM   1043 C C     . TRP C 3 49 ? 6.172   -3.230  15.297  1.00 50.84  ? 279 TRP A C     1 
ATOM   1044 O O     . TRP C 3 49 ? 6.785   -2.653  16.170  1.00 56.88  ? 279 TRP A O     1 
ATOM   1045 C CB    . TRP C 3 49 ? 4.007   -4.504  15.513  1.00 62.21  ? 279 TRP A CB    1 
ATOM   1046 C CG    . TRP C 3 49 ? 4.348   -5.009  16.900  1.00 57.32  ? 279 TRP A CG    1 
ATOM   1047 C CD1   . TRP C 3 49 ? 3.664   -4.711  18.049  1.00 63.25  ? 279 TRP A CD1   1 
ATOM   1048 C CD2   . TRP C 3 49 ? 5.473   -5.810  17.326  1.00 56.20  ? 279 TRP A CD2   1 
ATOM   1049 N NE1   . TRP C 3 49 ? 4.263   -5.290  19.137  1.00 55.50  ? 279 TRP A NE1   1 
ATOM   1050 C CE2   . TRP C 3 49 ? 5.372   -5.965  18.726  1.00 59.83  ? 279 TRP A CE2   1 
ATOM   1051 C CE3   . TRP C 3 49 ? 6.537   -6.429  16.675  1.00 60.94  ? 279 TRP A CE3   1 
ATOM   1052 C CZ2   . TRP C 3 49 ? 6.287   -6.694  19.468  1.00 64.63  ? 279 TRP A CZ2   1 
ATOM   1053 C CZ3   . TRP C 3 49 ? 7.433   -7.163  17.409  1.00 57.55  ? 279 TRP A CZ3   1 
ATOM   1054 C CH2   . TRP C 3 49 ? 7.329   -7.269  18.789  1.00 64.03  ? 279 TRP A CH2   1 
ATOM   1055 N N     . TYR C 3 50 ? 6.788   -3.998  14.395  1.00 55.97  ? 280 TYR A N     1 
ATOM   1056 C CA    . TYR C 3 50 ? 8.242   -4.151  14.343  1.00 52.23  ? 280 TYR A CA    1 
ATOM   1057 C C     . TYR C 3 50 ? 8.959   -2.796  14.286  1.00 50.54  ? 280 TYR A C     1 
ATOM   1058 O O     . TYR C 3 50 ? 9.969   -2.586  14.941  1.00 60.64  ? 280 TYR A O     1 
ATOM   1059 C CB    . TYR C 3 50 ? 8.656   -4.993  13.137  1.00 52.87  ? 280 TYR A CB    1 
ATOM   1060 C CG    . TYR C 3 50 ? 9.193   -6.376  13.468  1.00 50.66  ? 280 TYR A CG    1 
ATOM   1061 C CD1   . TYR C 3 50 ? 8.380   -7.488  13.566  1.00 50.38  ? 280 TYR A CD1   1 
ATOM   1062 C CD2   . TYR C 3 50 ? 10.543  -6.567  13.621  1.00 53.00  ? 280 TYR A CD2   1 
ATOM   1063 C CE1   . TYR C 3 50 ? 8.907   -8.738  13.868  1.00 52.78  ? 280 TYR A CE1   1 
ATOM   1064 C CE2   . TYR C 3 50 ? 11.081  -7.804  13.904  1.00 57.73  ? 280 TYR A CE2   1 
ATOM   1065 C CZ    . TYR C 3 50 ? 10.265  -8.903  14.035  1.00 53.23  ? 280 TYR A CZ    1 
ATOM   1066 O OH    . TYR C 3 50 ? 10.880  -10.101 14.318  1.00 58.32  ? 280 TYR A OH    1 
ATOM   1067 N N     . GLN C 3 51 ? 8.418   -1.831  13.553  1.00 50.95  ? 281 GLN A N     1 
ATOM   1068 C CA    . GLN C 3 51 ? 9.104   -0.559  13.432  1.00 49.42  ? 281 GLN A CA    1 
ATOM   1069 C C     . GLN C 3 51 ? 9.015   0.235   14.740  1.00 56.06  ? 281 GLN A C     1 
ATOM   1070 O O     . GLN C 3 51 ? 9.959   0.909   15.134  1.00 56.01  ? 281 GLN A O     1 
ATOM   1071 C CB    . GLN C 3 51 ? 8.360   0.172   12.320  1.00 54.17  ? 281 GLN A CB    1 
ATOM   1072 C CG    . GLN C 3 51 ? 8.925   1.554   12.024  1.00 54.44  ? 281 GLN A CG    1 
ATOM   1073 C CD    . GLN C 3 51 ? 10.371  1.449   11.605  1.00 59.30  ? 281 GLN A CD    1 
ATOM   1074 O OE1   . GLN C 3 51 ? 10.763  0.529   10.874  1.00 58.33  ? 281 GLN A OE1   1 
ATOM   1075 N NE2   . GLN C 3 51 ? 11.191  2.341   12.130  1.00 56.13  ? 281 GLN A NE2   1 
ATOM   1076 N N     . ASN C 3 52 ? 7.823   0.224   15.364  1.00 64.29  ? 282 ASN A N     1 
ATOM   1077 C CA    . ASN C 3 52 ? 7.601   0.838   16.660  1.00 57.71  ? 282 ASN A CA    1 
ATOM   1078 C C     . ASN C 3 52 ? 8.444   0.099   17.691  1.00 66.59  ? 282 ASN A C     1 
ATOM   1079 O O     . ASN C 3 52 ? 8.854   0.703   18.684  1.00 72.82  ? 282 ASN A O     1 
ATOM   1080 C CB    . ASN C 3 52 ? 6.133   0.780   17.076  1.00 58.72  ? 282 ASN A CB    1 
ATOM   1081 C CG    . ASN C 3 52 ? 5.317   1.871   16.428  1.00 56.98  ? 282 ASN A CG    1 
ATOM   1082 O OD1   . ASN C 3 52 ? 5.802   2.996   16.307  1.00 48.55  ? 282 ASN A OD1   1 
ATOM   1083 N ND2   . ASN C 3 52 ? 4.066   1.611   16.074  1.00 53.61  ? 282 ASN A ND2   1 
ATOM   1084 N N     . ARG C 3 53 ? 8.699   -1.205  17.447  1.00 58.95  ? 283 ARG A N     1 
ATOM   1085 C CA    . ARG C 3 53 ? 9.386   -2.016  18.436  1.00 61.24  ? 283 ARG A CA    1 
ATOM   1086 C C     . ARG C 3 53 ? 10.845  -1.614  18.433  1.00 62.85  ? 283 ARG A C     1 
ATOM   1087 O O     . ARG C 3 53 ? 11.459  -1.507  19.486  1.00 64.03  ? 283 ARG A O     1 
ATOM   1088 C CB    . ARG C 3 53 ? 9.239   -3.522  18.228  1.00 70.21  ? 283 ARG A CB    1 
ATOM   1089 C CG    . ARG C 3 53 ? 9.840   -4.392  19.328  1.00 79.06  ? 283 ARG A CG    1 
ATOM   1090 C CD    . ARG C 3 53 ? 9.231   -4.233  20.732  1.00 77.89  ? 283 ARG A CD    1 
ATOM   1091 N NE    . ARG C 3 53 ? 9.944   -4.960  21.795  1.00 80.78  ? 283 ARG A NE    1 
ATOM   1092 C CZ    . ARG C 3 53 ? 11.115  -4.642  22.362  1.00 82.16  ? 283 ARG A CZ    1 
ATOM   1093 N NH1   . ARG C 3 53 ? 11.668  -5.492  23.206  1.00 81.90  ? 283 ARG A NH1   1 
ATOM   1094 N NH2   . ARG C 3 53 ? 11.745  -3.511  22.076  1.00 80.97  ? 283 ARG A NH2   1 
ATOM   1095 N N     . ARG C 3 54 ? 11.359  -1.342  17.234  1.00 63.14  ? 284 ARG A N     1 
ATOM   1096 C CA    . ARG C 3 54 ? 12.745  -0.922  17.077  1.00 69.04  ? 284 ARG A CA    1 
ATOM   1097 C C     . ARG C 3 54 ? 12.965  0.427   17.763  1.00 66.14  ? 284 ARG A C     1 
ATOM   1098 O O     . ARG C 3 54 ? 13.969  0.603   18.445  1.00 73.34  ? 284 ARG A O     1 
ATOM   1099 C CB    . ARG C 3 54 ? 13.156  -0.929  15.597  1.00 65.48  ? 284 ARG A CB    1 
ATOM   1100 C CG    . ARG C 3 54 ? 13.371  -2.337  15.055  1.00 60.77  ? 284 ARG A CG    1 
ATOM   1101 C CD    . ARG C 3 54 ? 13.893  -2.373  13.628  1.00 62.61  ? 284 ARG A CD    1 
ATOM   1102 N NE    . ARG C 3 54 ? 12.995  -1.835  12.596  1.00 60.54  ? 284 ARG A NE    1 
ATOM   1103 C CZ    . ARG C 3 54 ? 12.300  -2.612  11.778  1.00 55.08  ? 284 ARG A CZ    1 
ATOM   1104 N NH1   . ARG C 3 54 ? 12.399  -3.918  11.929  1.00 55.17  ? 284 ARG A NH1   1 
ATOM   1105 N NH2   . ARG C 3 54 ? 11.524  -2.103  10.837  1.00 51.87  ? 284 ARG A NH2   1 
ATOM   1106 N N     . THR C 3 55 ? 12.015  1.361   17.620  1.00 65.14  ? 285 THR A N     1 
ATOM   1107 C CA    . THR C 3 55 ? 12.154  2.676   18.235  1.00 68.33  ? 285 THR A CA    1 
ATOM   1108 C C     . THR C 3 55 ? 12.333  2.516   19.736  1.00 70.95  ? 285 THR A C     1 
ATOM   1109 O O     . THR C 3 55 ? 13.175  3.195   20.317  1.00 69.10  ? 285 THR A O     1 
ATOM   1110 C CB    . THR C 3 55 ? 10.943  3.549   17.955  1.00 69.76  ? 285 THR A CB    1 
ATOM   1111 O OG1   . THR C 3 55 ? 10.413  3.076   16.727  1.00 70.36  ? 285 THR A OG1   1 
ATOM   1112 C CG2   . THR C 3 55 ? 11.313  5.007   17.819  1.00 76.95  ? 285 THR A CG2   1 
ATOM   1113 N N     . LYS C 3 56 ? 11.550  1.602   20.335  1.00 72.30  ? 286 LYS A N     1 
ATOM   1114 C CA    . LYS C 3 56 ? 11.660  1.291   21.759  1.00 85.60  ? 286 LYS A CA    1 
ATOM   1115 C C     . LYS C 3 56 ? 13.007  0.627   22.057  1.00 86.48  ? 286 LYS A C     1 
ATOM   1116 O O     . LYS C 3 56 ? 13.674  0.994   23.028  1.00 86.31  ? 286 LYS A O     1 
ATOM   1117 C CB    . LYS C 3 56 ? 10.504  0.405   22.244  1.00 83.75  ? 286 LYS A CB    1 
ATOM   1118 C CG    . LYS C 3 56 ? 10.530  0.008   23.719  1.00 87.10  ? 286 LYS A CG    1 
ATOM   1119 C CD    . LYS C 3 56 ? 9.285   -0.750  24.179  1.00 85.99  ? 286 LYS A CD    1 
ATOM   1120 C CE    . LYS C 3 56 ? 9.552   -1.622  25.364  1.00 87.41  ? 286 LYS A CE    1 
ATOM   1121 N NZ    . LYS C 3 56 ? 8.392   -2.431  25.740  1.00 85.84  ? 286 LYS A NZ    1 
ATOM   1122 N N     . TRP C 3 57 ? 13.387  -0.340  21.210  1.00 74.24  ? 287 TRP A N     1 
ATOM   1123 C CA    . TRP C 3 57 ? 14.669  -1.021  21.307  1.00 85.30  ? 287 TRP A CA    1 
ATOM   1124 C C     . TRP C 3 57 ? 15.831  -0.032  21.342  1.00 86.11  ? 287 TRP A C     1 
ATOM   1125 O O     . TRP C 3 57 ? 16.657  -0.091  22.251  1.00 88.99  ? 287 TRP A O     1 
ATOM   1126 C CB    . TRP C 3 57 ? 14.812  -1.971  20.116  1.00 88.81  ? 287 TRP A CB    1 
ATOM   1127 C CG    . TRP C 3 57 ? 16.163  -2.602  19.955  1.00 86.43  ? 287 TRP A CG    1 
ATOM   1128 C CD1   . TRP C 3 57 ? 16.919  -3.208  20.911  1.00 89.91  ? 287 TRP A CD1   1 
ATOM   1129 C CD2   . TRP C 3 57 ? 16.900  -2.705  18.720  1.00 93.74  ? 287 TRP A CD2   1 
ATOM   1130 N NE1   . TRP C 3 57 ? 18.081  -3.681  20.361  1.00 96.65  ? 287 TRP A NE1   1 
ATOM   1131 C CE2   . TRP C 3 57 ? 18.102  -3.387  19.020  1.00 102.86 ? 287 TRP A CE2   1 
ATOM   1132 C CE3   . TRP C 3 57 ? 16.668  -2.292  17.399  1.00 93.70  ? 287 TRP A CE3   1 
ATOM   1133 C CZ2   . TRP C 3 57 ? 19.065  -3.655  18.043  1.00 102.00 ? 287 TRP A CZ2   1 
ATOM   1134 C CZ3   . TRP C 3 57 ? 17.619  -2.559  16.434  1.00 91.61  ? 287 TRP A CZ3   1 
ATOM   1135 C CH2   . TRP C 3 57 ? 18.802  -3.229  16.757  1.00 97.53  ? 287 TRP A CH2   1 
ATOM   1136 N N     . LYS C 3 58 ? 15.881  0.871   20.349  1.00 89.46  ? 288 LYS A N     1 
ATOM   1137 C CA    . LYS C 3 58 ? 16.944  1.869   20.250  1.00 89.16  ? 288 LYS A CA    1 
ATOM   1138 C C     . LYS C 3 58 ? 16.971  2.713   21.520  1.00 84.18  ? 288 LYS A C     1 
ATOM   1139 O O     . LYS C 3 58 ? 18.041  3.118   21.957  1.00 83.86  ? 288 LYS A O     1 
ATOM   1140 C CB    . LYS C 3 58 ? 16.830  2.802   19.032  1.00 89.06  ? 288 LYS A CB    1 
ATOM   1141 C CG    . LYS C 3 58 ? 16.951  2.139   17.647  1.00 95.66  ? 288 LYS A CG    1 
ATOM   1142 C CD    . LYS C 3 58 ? 16.987  3.112   16.467  1.00 102.74 ? 288 LYS A CD    1 
ATOM   1143 C CE    . LYS C 3 58 ? 16.972  2.482   15.084  1.00 109.15 ? 288 LYS A CE    1 
ATOM   1144 N NZ    . LYS C 3 58 ? 15.626  2.150   14.589  1.00 113.39 ? 288 LYS A NZ    1 
ATOM   1145 N N     . ARG C 3 59 ? 15.781  2.967   22.084  1.00 90.71  ? 289 ARG A N     1 
ATOM   1146 C CA    . ARG C 3 59 ? 15.616  3.685   23.344  1.00 100.89 ? 289 ARG A CA    1 
ATOM   1147 C C     . ARG C 3 59 ? 16.265  2.902   24.487  1.00 103.82 ? 289 ARG A C     1 
ATOM   1148 O O     . ARG C 3 59 ? 16.958  3.490   25.311  1.00 108.60 ? 289 ARG A O     1 
ATOM   1149 C CB    . ARG C 3 59 ? 14.128  3.965   23.612  1.00 103.11 ? 289 ARG A CB    1 
ATOM   1150 C CG    . ARG C 3 59 ? 13.777  4.809   24.830  1.00 109.18 ? 289 ARG A CG    1 
ATOM   1151 C CD    . ARG C 3 59 ? 14.182  6.291   24.739  1.00 118.90 ? 289 ARG A CD    1 
ATOM   1152 N NE    . ARG C 3 59 ? 15.517  6.667   25.237  1.00 124.32 ? 289 ARG A NE    1 
ATOM   1153 C CZ    . ARG C 3 59 ? 15.946  6.634   26.506  1.00 126.34 ? 289 ARG A CZ    1 
ATOM   1154 N NH1   . ARG C 3 59 ? 15.198  6.123   27.468  1.00 129.27 ? 289 ARG A NH1   1 
ATOM   1155 N NH2   . ARG C 3 59 ? 17.142  7.104   26.817  1.00 129.09 ? 289 ARG A NH2   1 
ATOM   1156 N N     . GLN C 3 60 ? 16.074  1.577   24.517  1.00 102.96 ? 290 GLN A N     1 
ATOM   1157 C CA    . GLN C 3 60 ? 16.708  0.741   25.527  1.00 110.63 ? 290 GLN A CA    1 
ATOM   1158 C C     . GLN C 3 60 ? 18.209  0.575   25.287  1.00 123.38 ? 290 GLN A C     1 
ATOM   1159 O O     . GLN C 3 60 ? 18.929  0.212   26.212  1.00 139.59 ? 290 GLN A O     1 
ATOM   1160 C CB    . GLN C 3 60 ? 16.018  -0.617  25.634  1.00 109.76 ? 290 GLN A CB    1 
ATOM   1161 C CG    . GLN C 3 60 ? 14.933  -0.652  26.704  1.00 110.52 ? 290 GLN A CG    1 
ATOM   1162 C CD    . GLN C 3 60 ? 13.700  -1.416  26.279  1.00 107.84 ? 290 GLN A CD    1 
ATOM   1163 O OE1   . GLN C 3 60 ? 13.727  -2.251  25.366  1.00 110.45 ? 290 GLN A OE1   1 
ATOM   1164 N NE2   . GLN C 3 60 ? 12.594  -1.113  26.938  1.00 107.58 ? 290 GLN A NE2   1 
ATOM   1165 N N     . THR C 3 61 ? 18.691  0.817   24.062  1.00 131.13 ? 291 THR A N     1 
ATOM   1166 C CA    . THR C 3 61 ? 20.127  0.840   23.804  1.00 134.79 ? 291 THR A CA    1 
ATOM   1167 C C     . THR C 3 61 ? 20.705  2.185   24.257  1.00 142.89 ? 291 THR A C     1 
ATOM   1168 O O     . THR C 3 61 ? 21.879  2.261   24.618  1.00 144.20 ? 291 THR A O     1 
ATOM   1169 C CB    . THR C 3 61 ? 20.393  0.543   22.326  1.00 126.58 ? 291 THR A CB    1 
ATOM   1170 O OG1   . THR C 3 61 ? 19.866  -0.768  22.129  1.00 115.66 ? 291 THR A OG1   1 
ATOM   1171 C CG2   . THR C 3 61 ? 21.867  0.594   21.960  1.00 123.68 ? 291 THR A CG2   1 
ATOM   1172 N N     . ALA C 3 62 ? 19.868  3.234   24.250  1.00 148.24 ? 292 ALA A N     1 
ATOM   1173 C CA    . ALA C 3 62 ? 20.241  4.545   24.763  1.00 157.15 ? 292 ALA A CA    1 
ATOM   1174 C C     . ALA C 3 62 ? 19.955  4.657   26.264  1.00 176.14 ? 292 ALA A C     1 
ATOM   1175 O O     . ALA C 3 62 ? 20.362  5.645   26.876  1.00 168.84 ? 292 ALA A O     1 
ATOM   1176 C CB    . ALA C 3 62 ? 19.507  5.622   23.990  1.00 151.19 ? 292 ALA A CB    1 
ATOM   1177 N N     . VAL C 3 63 ? 19.262  3.653   26.846  1.00 194.37 ? 293 VAL A N     1 
ATOM   1178 C CA    . VAL C 3 63 ? 18.919  3.634   28.268  1.00 195.06 ? 293 VAL A CA    1 
ATOM   1179 C C     . VAL C 3 63 ? 20.094  3.060   29.071  1.00 206.95 ? 293 VAL A C     1 
ATOM   1180 O O     . VAL C 3 63 ? 19.982  2.896   30.286  1.00 207.77 ? 293 VAL A O     1 
ATOM   1181 C CB    . VAL C 3 63 ? 17.589  2.894   28.573  1.00 176.44 ? 293 VAL A CB    1 
ATOM   1182 C CG1   . VAL C 3 63 ? 17.744  1.385   28.757  1.00 165.67 ? 293 VAL A CG1   1 
ATOM   1183 C CG2   . VAL C 3 63 ? 16.869  3.475   29.788  1.00 175.15 ? 293 VAL A CG2   1 
ATOM   1184 N N     . GLY C 3 64 ? 21.229  2.797   28.394  1.00 151.92 ? 294 GLY A N     1 
ATOM   1185 C CA    . GLY C 3 64 ? 22.443  2.292   29.023  1.00 145.03 ? 294 GLY A CA    1 
ATOM   1186 C C     . GLY C 3 64 ? 22.854  0.935   28.468  1.00 137.45 ? 294 GLY A C     1 
ATOM   1187 O O     . GLY C 3 64 ? 22.381  0.598   27.359  1.00 123.17 ? 294 GLY A O     1 
ATOM   1188 N N     . LYS D 4 1  ? -2.966  2.377   -13.336 1.00 112.69 ? 230 LYS E N     1 
ATOM   1189 C CA    . LYS D 4 1  ? -4.080  3.011   -12.581 1.00 119.79 ? 230 LYS E CA    1 
ATOM   1190 C C     . LYS D 4 1  ? -3.773  4.505   -12.429 1.00 113.67 ? 230 LYS E C     1 
ATOM   1191 O O     . LYS D 4 1  ? -4.484  5.339   -12.985 1.00 110.55 ? 230 LYS E O     1 
ATOM   1192 C CB    . LYS D 4 1  ? -4.323  2.230   -11.278 1.00 125.76 ? 230 LYS E CB    1 
ATOM   1193 C CG    . LYS D 4 1  ? -5.656  2.484   -10.576 1.00 129.53 ? 230 LYS E CG    1 
ATOM   1194 C CD    . LYS D 4 1  ? -6.903  2.095   -11.371 1.00 135.84 ? 230 LYS E CD    1 
ATOM   1195 C CE    . LYS D 4 1  ? -8.178  2.676   -10.818 1.00 139.60 ? 230 LYS E CE    1 
ATOM   1196 N NZ    . LYS D 4 1  ? -8.126  4.141   -10.762 1.00 139.82 ? 230 LYS E NZ    1 
ATOM   1197 N N     . LYS D 4 2  ? -2.703  4.839   -11.698 1.00 105.48 ? 231 LYS E N     1 
ATOM   1198 C CA    . LYS D 4 2  ? -2.180  6.201   -11.677 1.00 111.05 ? 231 LYS E CA    1 
ATOM   1199 C C     . LYS D 4 2  ? -1.193  6.349   -12.839 1.00 99.88  ? 231 LYS E C     1 
ATOM   1200 O O     . LYS D 4 2  ? -0.169  5.672   -12.885 1.00 93.35  ? 231 LYS E O     1 
ATOM   1201 C CB    . LYS D 4 2  ? -1.585  6.608   -10.315 1.00 115.48 ? 231 LYS E CB    1 
ATOM   1202 C CG    . LYS D 4 2  ? -1.039  5.494   -9.393  1.00 121.74 ? 231 LYS E CG    1 
ATOM   1203 C CD    . LYS D 4 2  ? 0.264   4.813   -9.810  1.00 117.54 ? 231 LYS E CD    1 
ATOM   1204 C CE    . LYS D 4 2  ? 0.308   3.309   -9.592  1.00 120.36 ? 231 LYS E CE    1 
ATOM   1205 N NZ    . LYS D 4 2  ? -0.400  2.471   -10.574 1.00 118.73 ? 231 LYS E NZ    1 
ATOM   1206 N N     . PRO D 4 3  ? -1.474  7.179   -13.867 1.00 90.37  ? 232 PRO E N     1 
ATOM   1207 C CA    . PRO D 4 3  ? -0.514  7.364   -14.948 1.00 90.29  ? 232 PRO E CA    1 
ATOM   1208 C C     . PRO D 4 3  ? 0.801   7.834   -14.336 1.00 83.17  ? 232 PRO E C     1 
ATOM   1209 O O     . PRO D 4 3  ? 0.807   8.565   -13.345 1.00 85.19  ? 232 PRO E O     1 
ATOM   1210 C CB    . PRO D 4 3  ? -1.160  8.398   -15.890 1.00 90.41  ? 232 PRO E CB    1 
ATOM   1211 C CG    . PRO D 4 3  ? -2.636  8.271   -15.591 1.00 99.06  ? 232 PRO E CG    1 
ATOM   1212 C CD    . PRO D 4 3  ? -2.719  7.924   -14.098 1.00 98.08  ? 232 PRO E CD    1 
ATOM   1213 N N     . ARG D 4 4  ? 1.897   7.349   -14.924 1.00 72.69  ? 233 ARG E N     1 
ATOM   1214 C CA    . ARG D 4 4  ? 3.243   7.775   -14.597 1.00 65.00  ? 233 ARG E CA    1 
ATOM   1215 C C     . ARG D 4 4  ? 3.350   9.258   -14.913 1.00 63.66  ? 233 ARG E C     1 
ATOM   1216 O O     . ARG D 4 4  ? 2.730   9.741   -15.859 1.00 71.00  ? 233 ARG E O     1 
ATOM   1217 C CB    . ARG D 4 4  ? 4.170   6.893   -15.438 1.00 66.90  ? 233 ARG E CB    1 
ATOM   1218 C CG    . ARG D 4 4  ? 5.641   7.221   -15.256 1.00 70.64  ? 233 ARG E CG    1 
ATOM   1219 C CD    . ARG D 4 4  ? 6.535   6.056   -15.634 1.00 68.51  ? 233 ARG E CD    1 
ATOM   1220 N NE    . ARG D 4 4  ? 7.880   6.504   -15.284 1.00 63.58  ? 233 ARG E NE    1 
ATOM   1221 C CZ    . ARG D 4 4  ? 8.626   5.919   -14.385 1.00 59.24  ? 233 ARG E CZ    1 
ATOM   1222 N NH1   . ARG D 4 4  ? 8.283   4.770   -13.873 1.00 65.46  ? 233 ARG E NH1   1 
ATOM   1223 N NH2   . ARG D 4 4  ? 9.731   6.476   -13.976 1.00 58.60  ? 233 ARG E NH2   1 
ATOM   1224 N N     . LYS D 4 5  ? 4.066   10.008  -14.081 1.00 59.81  ? 234 LYS E N     1 
ATOM   1225 C CA    . LYS D 4 5  ? 4.171   11.426  -14.367 1.00 58.51  ? 234 LYS E CA    1 
ATOM   1226 C C     . LYS D 4 5  ? 5.124   11.577  -15.543 1.00 65.40  ? 234 LYS E C     1 
ATOM   1227 O O     . LYS D 4 5  ? 6.036   10.766  -15.701 1.00 72.04  ? 234 LYS E O     1 
ATOM   1228 C CB    . LYS D 4 5  ? 4.703   12.333  -13.258 1.00 55.30  ? 234 LYS E CB    1 
ATOM   1229 C CG    . LYS D 4 5  ? 4.109   12.148  -11.873 1.00 66.51  ? 234 LYS E CG    1 
ATOM   1230 C CD    . LYS D 4 5  ? 4.053   13.395  -10.996 1.00 76.35  ? 234 LYS E CD    1 
ATOM   1231 C CE    . LYS D 4 5  ? 4.277   13.192  -9.524  1.00 80.07  ? 234 LYS E CE    1 
ATOM   1232 N NZ    . LYS D 4 5  ? 3.911   11.848  -9.066  1.00 90.11  ? 234 LYS E NZ    1 
ATOM   1233 N N     . ALA D 4 6  ? 4.922   12.650  -16.318 1.00 64.52  ? 235 ALA E N     1 
ATOM   1234 C CA    . ALA D 4 6  ? 5.830   13.024  -17.383 1.00 64.81  ? 235 ALA E CA    1 
ATOM   1235 C C     . ALA D 4 6  ? 7.206   13.206  -16.772 1.00 62.32  ? 235 ALA E C     1 
ATOM   1236 O O     . ALA D 4 6  ? 7.308   13.618  -15.631 1.00 57.88  ? 235 ALA E O     1 
ATOM   1237 C CB    . ALA D 4 6  ? 5.355   14.272  -18.094 1.00 65.54  ? 235 ALA E CB    1 
ATOM   1238 N N     . ARG D 4 7  ? 8.245   12.858  -17.534 1.00 60.85  ? 236 ARG E N     1 
ATOM   1239 C CA    . ARG D 4 7  ? 9.621   12.959  -17.080 1.00 55.74  ? 236 ARG E CA    1 
ATOM   1240 C C     . ARG D 4 7  ? 10.022  14.406  -17.235 1.00 61.08  ? 236 ARG E C     1 
ATOM   1241 O O     . ARG D 4 7  ? 9.980   14.925  -18.343 1.00 73.06  ? 236 ARG E O     1 
ATOM   1242 C CB    . ARG D 4 7  ? 10.458  12.007  -17.941 1.00 63.06  ? 236 ARG E CB    1 
ATOM   1243 C CG    . ARG D 4 7  ? 11.880  11.773  -17.468 1.00 64.56  ? 236 ARG E CG    1 
ATOM   1244 C CD    . ARG D 4 7  ? 12.816  11.362  -18.588 1.00 57.81  ? 236 ARG E CD    1 
ATOM   1245 N NE    . ARG D 4 7  ? 14.201  11.716  -18.238 1.00 51.47  ? 236 ARG E NE    1 
ATOM   1246 C CZ    . ARG D 4 7  ? 15.023  10.916  -17.568 1.00 55.52  ? 236 ARG E CZ    1 
ATOM   1247 N NH1   . ARG D 4 7  ? 14.601  9.708   -17.172 1.00 59.94  ? 236 ARG E NH1   1 
ATOM   1248 N NH2   . ARG D 4 7  ? 16.239  11.337  -17.257 1.00 55.14  ? 236 ARG E NH2   1 
ATOM   1249 N N     . THR D 4 8  ? 10.270  15.084  -16.112 1.00 65.29  ? 237 THR E N     1 
ATOM   1250 C CA    . THR D 4 8  ? 10.586  16.504  -16.140 1.00 61.70  ? 237 THR E CA    1 
ATOM   1251 C C     . THR D 4 8  ? 11.795  16.690  -17.046 1.00 63.10  ? 237 THR E C     1 
ATOM   1252 O O     . THR D 4 8  ? 12.743  15.920  -16.912 1.00 71.18  ? 237 THR E O     1 
ATOM   1253 C CB    . THR D 4 8  ? 10.933  17.014  -14.744 1.00 61.36  ? 237 THR E CB    1 
ATOM   1254 O OG1   . THR D 4 8  ? 9.767   17.054  -13.925 1.00 55.57  ? 237 THR E OG1   1 
ATOM   1255 C CG2   . THR D 4 8  ? 11.549  18.399  -14.804 1.00 60.84  ? 237 THR E CG2   1 
ATOM   1256 N N     . ALA D 4 9  ? 11.751  17.689  -17.938 1.00 65.29  ? 238 ALA E N     1 
ATOM   1257 C CA    . ALA D 4 9  ? 12.937  18.128  -18.663 1.00 63.69  ? 238 ALA E CA    1 
ATOM   1258 C C     . ALA D 4 9  ? 13.389  19.437  -18.036 1.00 60.35  ? 238 ALA E C     1 
ATOM   1259 O O     . ALA D 4 9  ? 12.740  20.469  -18.219 1.00 64.21  ? 238 ALA E O     1 
ATOM   1260 C CB    . ALA D 4 9  ? 12.677  18.245  -20.160 1.00 66.61  ? 238 ALA E CB    1 
ATOM   1261 N N     . PHE D 4 10 ? 14.464  19.349  -17.237 1.00 57.87  ? 239 PHE E N     1 
ATOM   1262 C CA    . PHE D 4 10 ? 15.041  20.506  -16.583 1.00 58.83  ? 239 PHE E CA    1 
ATOM   1263 C C     . PHE D 4 10 ? 15.740  21.368  -17.644 1.00 67.86  ? 239 PHE E C     1 
ATOM   1264 O O     . PHE D 4 10 ? 16.259  20.841  -18.621 1.00 64.96  ? 239 PHE E O     1 
ATOM   1265 C CB    . PHE D 4 10 ? 15.997  19.993  -15.507 1.00 56.05  ? 239 PHE E CB    1 
ATOM   1266 C CG    . PHE D 4 10 ? 15.352  19.358  -14.277 1.00 63.00  ? 239 PHE E CG    1 
ATOM   1267 C CD1   . PHE D 4 10 ? 14.695  20.144  -13.327 1.00 65.29  ? 239 PHE E CD1   1 
ATOM   1268 C CD2   . PHE D 4 10 ? 15.387  17.975  -14.070 1.00 61.33  ? 239 PHE E CD2   1 
ATOM   1269 C CE1   . PHE D 4 10 ? 14.097  19.566  -12.210 1.00 58.34  ? 239 PHE E CE1   1 
ATOM   1270 C CE2   . PHE D 4 10 ? 14.813  17.409  -12.932 1.00 57.46  ? 239 PHE E CE2   1 
ATOM   1271 C CZ    . PHE D 4 10 ? 14.167  18.196  -12.020 1.00 53.70  ? 239 PHE E CZ    1 
ATOM   1272 N N     . SER D 4 11 ? 15.758  22.689  -17.453 1.00 61.98  ? 240 SER E N     1 
ATOM   1273 C CA    . SER D 4 11 ? 16.521  23.564  -18.314 1.00 63.00  ? 240 SER E CA    1 
ATOM   1274 C C     . SER D 4 11 ? 17.975  23.521  -17.847 1.00 69.70  ? 240 SER E C     1 
ATOM   1275 O O     . SER D 4 11 ? 18.259  23.160  -16.703 1.00 68.39  ? 240 SER E O     1 
ATOM   1276 C CB    . SER D 4 11 ? 15.968  24.963  -18.307 1.00 60.08  ? 240 SER E CB    1 
ATOM   1277 O OG    . SER D 4 11 ? 16.449  25.669  -17.173 1.00 64.07  ? 240 SER E OG    1 
ATOM   1278 N N     . ASP D 4 12 ? 18.884  23.842  -18.776 1.00 77.84  ? 241 ASP E N     1 
ATOM   1279 C CA    . ASP D 4 12 ? 20.290  24.077  -18.495 1.00 77.67  ? 241 ASP E CA    1 
ATOM   1280 C C     . ASP D 4 12 ? 20.492  24.881  -17.213 1.00 72.33  ? 241 ASP E C     1 
ATOM   1281 O O     . ASP D 4 12 ? 21.361  24.525  -16.418 1.00 69.98  ? 241 ASP E O     1 
ATOM   1282 C CB    . ASP D 4 12 ? 20.949  24.747  -19.690 1.00 80.94  ? 241 ASP E CB    1 
ATOM   1283 C CG    . ASP D 4 12 ? 21.257  23.771  -20.814 1.00 87.59  ? 241 ASP E CG    1 
ATOM   1284 O OD1   . ASP D 4 12 ? 21.254  22.558  -20.526 1.00 82.15  ? 241 ASP E OD1   1 
ATOM   1285 O OD2   . ASP D 4 12 ? 21.471  24.216  -21.970 1.00 98.05  ? 241 ASP E OD2   1 
ATOM   1286 N N     . HIS D 4 13 ? 19.699  25.950  -17.038 1.00 69.89  ? 242 HIS E N     1 
ATOM   1287 C CA    . HIS D 4 13 ? 19.832  26.851  -15.908 1.00 73.06  ? 242 HIS E CA    1 
ATOM   1288 C C     . HIS D 4 13 ? 19.377  26.141  -14.632 1.00 73.00  ? 242 HIS E C     1 
ATOM   1289 O O     . HIS D 4 13 ? 20.042  26.171  -13.597 1.00 69.98  ? 242 HIS E O     1 
ATOM   1290 C CB    . HIS D 4 13 ? 18.980  28.103  -16.121 1.00 79.54  ? 242 HIS E CB    1 
ATOM   1291 C CG    . HIS D 4 13 ? 19.003  29.032  -14.952 1.00 84.96  ? 242 HIS E CG    1 
ATOM   1292 N ND1   . HIS D 4 13 ? 20.158  29.322  -14.260 1.00 83.96  ? 242 HIS E ND1   1 
ATOM   1293 C CD2   . HIS D 4 13 ? 18.030  29.717  -14.343 1.00 86.78  ? 242 HIS E CD2   1 
ATOM   1294 C CE1   . HIS D 4 13 ? 19.878  30.148  -13.266 1.00 84.10  ? 242 HIS E CE1   1 
ATOM   1295 N NE2   . HIS D 4 13 ? 18.593  30.394  -13.298 1.00 89.97  ? 242 HIS E NE2   1 
ATOM   1296 N N     . GLN D 4 14 ? 18.241  25.463  -14.711 1.00 64.91  ? 243 GLN E N     1 
ATOM   1297 C CA    . GLN D 4 14 ? 17.755  24.787  -13.529 1.00 61.77  ? 243 GLN E CA    1 
ATOM   1298 C C     . GLN D 4 14 ? 18.800  23.772  -13.094 1.00 63.27  ? 243 GLN E C     1 
ATOM   1299 O O     . GLN D 4 14 ? 19.089  23.683  -11.897 1.00 58.44  ? 243 GLN E O     1 
ATOM   1300 C CB    . GLN D 4 14 ? 16.368  24.208  -13.744 1.00 57.79  ? 243 GLN E CB    1 
ATOM   1301 C CG    . GLN D 4 14 ? 15.311  25.262  -14.022 1.00 57.26  ? 243 GLN E CG    1 
ATOM   1302 C CD    . GLN D 4 14 ? 14.014  24.620  -14.449 1.00 64.44  ? 243 GLN E CD    1 
ATOM   1303 O OE1   . GLN D 4 14 ? 14.001  23.644  -15.209 1.00 64.99  ? 243 GLN E OE1   1 
ATOM   1304 N NE2   . GLN D 4 14 ? 12.913  25.149  -13.943 1.00 66.60  ? 243 GLN E NE2   1 
ATOM   1305 N N     . LEU D 4 15 ? 19.425  23.088  -14.067 1.00 62.71  ? 244 LEU E N     1 
ATOM   1306 C CA    . LEU D 4 15 ? 20.361  22.030  -13.732 1.00 61.30  ? 244 LEU E CA    1 
ATOM   1307 C C     . LEU D 4 15 ? 21.600  22.628  -13.086 1.00 63.60  ? 244 LEU E C     1 
ATOM   1308 O O     . LEU D 4 15 ? 22.165  22.096  -12.123 1.00 57.80  ? 244 LEU E O     1 
ATOM   1309 C CB    . LEU D 4 15 ? 20.748  21.268  -14.987 1.00 63.61  ? 244 LEU E CB    1 
ATOM   1310 C CG    . LEU D 4 15 ? 19.676  20.364  -15.588 1.00 69.62  ? 244 LEU E CG    1 
ATOM   1311 C CD1   . LEU D 4 15 ? 20.105  20.024  -17.041 1.00 73.19  ? 244 LEU E CD1   1 
ATOM   1312 C CD2   . LEU D 4 15 ? 19.458  19.103  -14.736 1.00 64.48  ? 244 LEU E CD2   1 
ATOM   1313 N N     . ASN D 4 16 ? 22.018  23.769  -13.634 1.00 68.60  ? 245 ASN E N     1 
ATOM   1314 C CA    . ASN D 4 16 ? 23.250  24.368  -13.162 1.00 70.13  ? 245 ASN E CA    1 
ATOM   1315 C C     . ASN D 4 16 ? 23.049  24.737  -11.696 1.00 68.37  ? 245 ASN E C     1 
ATOM   1316 O O     . ASN D 4 16 ? 23.895  24.365  -10.858 1.00 64.59  ? 245 ASN E O     1 
ATOM   1317 C CB    . ASN D 4 16 ? 23.744  25.401  -14.164 1.00 71.95  ? 245 ASN E CB    1 
ATOM   1318 C CG    . ASN D 4 16 ? 24.322  24.699  -15.374 1.00 81.12  ? 245 ASN E CG    1 
ATOM   1319 O OD1   . ASN D 4 16 ? 23.898  24.928  -16.512 1.00 94.94  ? 245 ASN E OD1   1 
ATOM   1320 N ND2   . ASN D 4 16 ? 25.277  23.810  -15.152 1.00 79.65  ? 245 ASN E ND2   1 
ATOM   1321 N N     . GLN D 4 17 ? 21.886  25.358  -11.411 1.00 66.71  ? 246 GLN E N     1 
ATOM   1322 C CA    . GLN D 4 17 ? 21.534  25.794  -10.064 1.00 72.02  ? 246 GLN E CA    1 
ATOM   1323 C C     . GLN D 4 17 ? 21.320  24.589  -9.146  1.00 65.82  ? 246 GLN E C     1 
ATOM   1324 O O     . GLN D 4 17 ? 21.752  24.611  -7.996  1.00 62.87  ? 246 GLN E O     1 
ATOM   1325 C CB    . GLN D 4 17 ? 20.274  26.656  -9.939  1.00 78.25  ? 246 GLN E CB    1 
ATOM   1326 C CG    . GLN D 4 17 ? 20.361  28.069  -10.521 1.00 85.00  ? 246 GLN E CG    1 
ATOM   1327 C CD    . GLN D 4 17 ? 21.720  28.710  -10.377 1.00 88.54  ? 246 GLN E CD    1 
ATOM   1328 O OE1   . GLN D 4 17 ? 22.648  28.434  -11.145 1.00 111.30 ? 246 GLN E OE1   1 
ATOM   1329 N NE2   . GLN D 4 17 ? 21.854  29.587  -9.401  1.00 80.41  ? 246 GLN E NE2   1 
ATOM   1330 N N     . LEU D 4 18 ? 20.679  23.526  -9.644  1.00 67.40  ? 247 LEU E N     1 
ATOM   1331 C CA    . LEU D 4 18 ? 20.548  22.328  -8.833  1.00 58.17  ? 247 LEU E CA    1 
ATOM   1332 C C     . LEU D 4 18 ? 21.941  21.816  -8.507  1.00 65.43  ? 247 LEU E C     1 
ATOM   1333 O O     . LEU D 4 18 ? 22.206  21.513  -7.349  1.00 60.49  ? 247 LEU E O     1 
ATOM   1334 C CB    . LEU D 4 18 ? 19.703  21.231  -9.467  1.00 60.00  ? 247 LEU E CB    1 
ATOM   1335 C CG    . LEU D 4 18 ? 18.201  21.529  -9.583  1.00 64.35  ? 247 LEU E CG    1 
ATOM   1336 C CD1   . LEU D 4 18 ? 17.555  20.536  -10.544 1.00 63.73  ? 247 LEU E CD1   1 
ATOM   1337 C CD2   . LEU D 4 18 ? 17.482  21.494  -8.223  1.00 63.95  ? 247 LEU E CD2   1 
ATOM   1338 N N     . GLU D 4 19 ? 22.846  21.792  -9.513  1.00 66.08  ? 248 GLU E N     1 
ATOM   1339 C CA    . GLU D 4 19 ? 24.166  21.212  -9.296  1.00 64.70  ? 248 GLU E CA    1 
ATOM   1340 C C     . GLU D 4 19 ? 24.961  22.093  -8.343  1.00 62.13  ? 248 GLU E C     1 
ATOM   1341 O O     . GLU D 4 19 ? 25.797  21.589  -7.608  1.00 64.97  ? 248 GLU E O     1 
ATOM   1342 C CB    . GLU D 4 19 ? 25.044  21.001  -10.529 1.00 69.39  ? 248 GLU E CB    1 
ATOM   1343 C CG    . GLU D 4 19 ? 24.485  20.055  -11.591 1.00 70.88  ? 248 GLU E CG    1 
ATOM   1344 C CD    . GLU D 4 19 ? 24.573  18.597  -11.231 1.00 69.35  ? 248 GLU E CD    1 
ATOM   1345 O OE1   . GLU D 4 19 ? 24.257  17.757  -12.101 1.00 73.41  ? 248 GLU E OE1   1 
ATOM   1346 O OE2   . GLU D 4 19 ? 24.948  18.326  -10.069 1.00 69.50  ? 248 GLU E OE2   1 
ATOM   1347 N N     . ARG D 4 20 ? 24.728  23.407  -8.385  1.00 65.05  ? 249 ARG E N     1 
ATOM   1348 C CA    . ARG D 4 20 ? 25.432  24.307  -7.480  1.00 67.18  ? 249 ARG E CA    1 
ATOM   1349 C C     . ARG D 4 20 ? 24.934  24.104  -6.057  1.00 74.73  ? 249 ARG E C     1 
ATOM   1350 O O     . ARG D 4 20 ? 25.734  24.081  -5.129  1.00 79.72  ? 249 ARG E O     1 
ATOM   1351 C CB    . ARG D 4 20 ? 25.248  25.786  -7.814  1.00 66.35  ? 249 ARG E CB    1 
ATOM   1352 C CG    . ARG D 4 20 ? 26.410  26.275  -8.667  1.00 70.76  ? 249 ARG E CG    1 
ATOM   1353 C CD    . ARG D 4 20 ? 26.223  27.698  -9.151  1.00 70.79  ? 249 ARG E CD    1 
ATOM   1354 N NE    . ARG D 4 20 ? 26.854  28.758  -8.358  1.00 75.82  ? 249 ARG E NE    1 
ATOM   1355 C CZ    . ARG D 4 20 ? 26.664  30.028  -8.672  1.00 73.51  ? 249 ARG E CZ    1 
ATOM   1356 N NH1   . ARG D 4 20 ? 25.851  30.326  -9.677  1.00 74.41  ? 249 ARG E NH1   1 
ATOM   1357 N NH2   . ARG D 4 20 ? 27.247  30.979  -7.990  1.00 75.64  ? 249 ARG E NH2   1 
ATOM   1358 N N     . SER D 4 21 ? 23.614  23.950  -5.899  1.00 73.03  ? 250 SER E N     1 
ATOM   1359 C CA    . SER D 4 21 ? 23.048  23.655  -4.597  1.00 77.33  ? 250 SER E CA    1 
ATOM   1360 C C     . SER D 4 21 ? 23.750  22.439  -3.998  1.00 66.82  ? 250 SER E C     1 
ATOM   1361 O O     . SER D 4 21 ? 24.220  22.462  -2.866  1.00 68.97  ? 250 SER E O     1 
ATOM   1362 C CB    . SER D 4 21 ? 21.544  23.436  -4.698  1.00 79.32  ? 250 SER E CB    1 
ATOM   1363 O OG    . SER D 4 21 ? 20.954  23.314  -3.411  1.00 79.69  ? 250 SER E OG    1 
ATOM   1364 N N     . PHE D 4 22 ? 23.850  21.388  -4.807  1.00 66.85  ? 251 PHE E N     1 
ATOM   1365 C CA    . PHE D 4 22 ? 24.298  20.090  -4.340  1.00 63.89  ? 251 PHE E CA    1 
ATOM   1366 C C     . PHE D 4 22 ? 25.760  20.157  -3.938  1.00 71.88  ? 251 PHE E C     1 
ATOM   1367 O O     . PHE D 4 22 ? 26.212  19.408  -3.074  1.00 79.50  ? 251 PHE E O     1 
ATOM   1368 C CB    . PHE D 4 22 ? 24.053  19.094  -5.469  1.00 56.59  ? 251 PHE E CB    1 
ATOM   1369 C CG    . PHE D 4 22 ? 24.421  17.684  -5.068  1.00 62.19  ? 251 PHE E CG    1 
ATOM   1370 C CD1   . PHE D 4 22 ? 23.511  16.888  -4.368  1.00 68.97  ? 251 PHE E CD1   1 
ATOM   1371 C CD2   . PHE D 4 22 ? 25.679  17.162  -5.356  1.00 67.29  ? 251 PHE E CD2   1 
ATOM   1372 C CE1   . PHE D 4 22 ? 23.846  15.586  -3.992  1.00 70.69  ? 251 PHE E CE1   1 
ATOM   1373 C CE2   . PHE D 4 22 ? 26.013  15.867  -4.963  1.00 74.47  ? 251 PHE E CE2   1 
ATOM   1374 C CZ    . PHE D 4 22 ? 25.091  15.073  -4.300  1.00 72.90  ? 251 PHE E CZ    1 
ATOM   1375 N N     . GLU D 4 23 ? 26.490  21.063  -4.596  1.00 84.44  ? 252 GLU E N     1 
ATOM   1376 C CA    . GLU D 4 23 ? 27.916  21.227  -4.377  1.00 84.82  ? 252 GLU E CA    1 
ATOM   1377 C C     . GLU D 4 23 ? 28.128  21.737  -2.955  1.00 87.35  ? 252 GLU E C     1 
ATOM   1378 O O     . GLU D 4 23 ? 29.037  21.277  -2.263  1.00 85.72  ? 252 GLU E O     1 
ATOM   1379 C CB    . GLU D 4 23 ? 28.486  22.175  -5.433  1.00 83.29  ? 252 GLU E CB    1 
ATOM   1380 C CG    . GLU D 4 23 ? 29.715  21.613  -6.132  1.00 91.20  ? 252 GLU E CG    1 
ATOM   1381 C CD    . GLU D 4 23 ? 29.442  20.772  -7.366  1.00 87.41  ? 252 GLU E CD    1 
ATOM   1382 O OE1   . GLU D 4 23 ? 29.240  21.395  -8.427  1.00 95.19  ? 252 GLU E OE1   1 
ATOM   1383 O OE2   . GLU D 4 23 ? 29.460  19.524  -7.286  1.00 84.66  ? 252 GLU E OE2   1 
ATOM   1384 N N     . ARG D 4 24 ? 27.258  22.665  -2.526  1.00 86.31  ? 253 ARG E N     1 
ATOM   1385 C CA    . ARG D 4 24 ? 27.300  23.191  -1.169  1.00 96.60  ? 253 ARG E CA    1 
ATOM   1386 C C     . ARG D 4 24 ? 26.732  22.174  -0.182  1.00 95.17  ? 253 ARG E C     1 
ATOM   1387 O O     . ARG D 4 24 ? 27.419  21.764  0.749   1.00 107.98 ? 253 ARG E O     1 
ATOM   1388 C CB    . ARG D 4 24 ? 26.524  24.504  -1.029  1.00 97.84  ? 253 ARG E CB    1 
ATOM   1389 C CG    . ARG D 4 24 ? 27.378  25.765  -1.040  1.00 108.42 ? 253 ARG E CG    1 
ATOM   1390 C CD    . ARG D 4 24 ? 26.508  26.992  -0.781  1.00 115.89 ? 253 ARG E CD    1 
ATOM   1391 N NE    . ARG D 4 24 ? 25.234  26.825  -1.493  1.00 115.73 ? 253 ARG E NE    1 
ATOM   1392 C CZ    . ARG D 4 24 ? 24.891  27.411  -2.638  1.00 120.23 ? 253 ARG E CZ    1 
ATOM   1393 N NH1   . ARG D 4 24 ? 25.560  28.467  -3.077  1.00 121.83 ? 253 ARG E NH1   1 
ATOM   1394 N NH2   . ARG D 4 24 ? 23.843  26.964  -3.315  1.00 115.45 ? 253 ARG E NH2   1 
ATOM   1395 N N     . GLN D 4 25 ? 25.478  21.765  -0.410  1.00 89.78  ? 254 GLN E N     1 
ATOM   1396 C CA    . GLN D 4 25 ? 24.722  20.994  0.563   1.00 81.64  ? 254 GLN E CA    1 
ATOM   1397 C C     . GLN D 4 25 ? 24.125  19.739  -0.067  1.00 73.06  ? 254 GLN E C     1 
ATOM   1398 O O     . GLN D 4 25 ? 23.267  19.831  -0.942  1.00 66.32  ? 254 GLN E O     1 
ATOM   1399 C CB    . GLN D 4 25 ? 23.592  21.880  1.064   1.00 78.98  ? 254 GLN E CB    1 
ATOM   1400 C CG    . GLN D 4 25 ? 24.074  23.128  1.782   1.00 86.78  ? 254 GLN E CG    1 
ATOM   1401 C CD    . GLN D 4 25 ? 22.957  23.747  2.583   1.00 96.42  ? 254 GLN E CD    1 
ATOM   1402 O OE1   . GLN D 4 25 ? 21.863  23.979  2.061   1.00 98.70  ? 254 GLN E OE1   1 
ATOM   1403 N NE2   . GLN D 4 25 ? 23.202  23.975  3.866   1.00 106.09 ? 254 GLN E NE2   1 
ATOM   1404 N N     . LYS D 4 26 ? 24.573  18.575  0.413   1.00 70.42  ? 255 LYS E N     1 
ATOM   1405 C CA    . LYS D 4 26 ? 24.042  17.305  -0.042  1.00 75.13  ? 255 LYS E CA    1 
ATOM   1406 C C     . LYS D 4 26 ? 22.604  17.185  0.448   1.00 67.21  ? 255 LYS E C     1 
ATOM   1407 O O     . LYS D 4 26 ? 21.777  16.549  -0.179  1.00 70.21  ? 255 LYS E O     1 
ATOM   1408 C CB    . LYS D 4 26 ? 24.888  16.128  0.460   1.00 84.71  ? 255 LYS E CB    1 
ATOM   1409 C CG    . LYS D 4 26 ? 26.406  16.216  0.217   1.00 96.85  ? 255 LYS E CG    1 
ATOM   1410 C CD    . LYS D 4 26 ? 26.881  16.045  -1.224  1.00 97.05  ? 255 LYS E CD    1 
ATOM   1411 C CE    . LYS D 4 26 ? 28.269  16.587  -1.458  1.00 104.56 ? 255 LYS E CE    1 
ATOM   1412 N NZ    . LYS D 4 26 ? 28.291  18.030  -1.744  1.00 97.58  ? 255 LYS E NZ    1 
ATOM   1413 N N     . TYR D 4 27 ? 22.304  17.827  1.568   1.00 68.81  ? 256 TYR E N     1 
ATOM   1414 C CA    . TYR D 4 27 ? 20.985  17.742  2.163   1.00 70.27  ? 256 TYR E CA    1 
ATOM   1415 C C     . TYR D 4 27 ? 20.426  19.152  2.309   1.00 68.71  ? 256 TYR E C     1 
ATOM   1416 O O     . TYR D 4 27 ? 21.153  20.050  2.701   1.00 72.93  ? 256 TYR E O     1 
ATOM   1417 C CB    . TYR D 4 27 ? 21.114  17.003  3.500   1.00 75.13  ? 256 TYR E CB    1 
ATOM   1418 C CG    . TYR D 4 27 ? 21.518  15.544  3.333   1.00 74.12  ? 256 TYR E CG    1 
ATOM   1419 C CD1   . TYR D 4 27 ? 20.598  14.579  2.940   1.00 72.59  ? 256 TYR E CD1   1 
ATOM   1420 C CD2   . TYR D 4 27 ? 22.828  15.137  3.538   1.00 79.02  ? 256 TYR E CD2   1 
ATOM   1421 C CE1   . TYR D 4 27 ? 20.969  13.256  2.757   1.00 71.75  ? 256 TYR E CE1   1 
ATOM   1422 C CE2   . TYR D 4 27 ? 23.210  13.816  3.372   1.00 77.37  ? 256 TYR E CE2   1 
ATOM   1423 C CZ    . TYR D 4 27 ? 22.278  12.877  2.984   1.00 73.20  ? 256 TYR E CZ    1 
ATOM   1424 O OH    . TYR D 4 27 ? 22.675  11.591  2.827   1.00 72.32  ? 256 TYR E OH    1 
ATOM   1425 N N     . LEU D 4 28 ? 19.155  19.334  1.932   1.00 65.37  ? 257 LEU E N     1 
ATOM   1426 C CA    . LEU D 4 28 ? 18.434  20.560  2.211   1.00 70.45  ? 257 LEU E CA    1 
ATOM   1427 C C     . LEU D 4 28 ? 17.435  20.321  3.335   1.00 77.69  ? 257 LEU E C     1 
ATOM   1428 O O     . LEU D 4 28 ? 16.755  19.290  3.370   1.00 75.01  ? 257 LEU E O     1 
ATOM   1429 C CB    . LEU D 4 28 ? 17.691  21.009  0.961   1.00 75.21  ? 257 LEU E CB    1 
ATOM   1430 C CG    . LEU D 4 28 ? 18.552  21.364  -0.254  1.00 67.65  ? 257 LEU E CG    1 
ATOM   1431 C CD1   . LEU D 4 28 ? 17.601  21.860  -1.320  1.00 73.38  ? 257 LEU E CD1   1 
ATOM   1432 C CD2   . LEU D 4 28 ? 19.602  22.379  0.063   1.00 71.10  ? 257 LEU E CD2   1 
ATOM   1433 N N     . SER D 4 29 ? 17.357  21.308  4.225   1.00 76.74  ? 258 SER E N     1 
ATOM   1434 C CA    . SER D 4 29 ? 16.210  21.495  5.088   1.00 80.23  ? 258 SER E CA    1 
ATOM   1435 C C     . SER D 4 29 ? 14.965  21.752  4.234   1.00 82.22  ? 258 SER E C     1 
ATOM   1436 O O     . SER D 4 29 ? 15.060  22.170  3.074   1.00 71.33  ? 258 SER E O     1 
ATOM   1437 C CB    . SER D 4 29 ? 16.468  22.652  6.008   1.00 83.34  ? 258 SER E CB    1 
ATOM   1438 O OG    . SER D 4 29 ? 16.640  23.818  5.217   1.00 83.43  ? 258 SER E OG    1 
ATOM   1439 N N     . VAL D 4 30 ? 13.788  21.545  4.839   1.00 79.72  ? 259 VAL E N     1 
ATOM   1440 C CA    . VAL D 4 30 ? 12.537  21.813  4.150   1.00 81.09  ? 259 VAL E CA    1 
ATOM   1441 C C     . VAL D 4 30 ? 12.592  23.229  3.556   1.00 81.15  ? 259 VAL E C     1 
ATOM   1442 O O     . VAL D 4 30 ? 12.443  23.396  2.345   1.00 74.77  ? 259 VAL E O     1 
ATOM   1443 C CB    . VAL D 4 30 ? 11.331  21.568  5.087   1.00 84.80  ? 259 VAL E CB    1 
ATOM   1444 C CG1   . VAL D 4 30 ? 10.064  22.287  4.633   1.00 89.17  ? 259 VAL E CG1   1 
ATOM   1445 C CG2   . VAL D 4 30 ? 11.041  20.076  5.243   1.00 84.24  ? 259 VAL E CG2   1 
ATOM   1446 N N     . GLN D 4 31 ? 12.865  24.234  4.402   1.00 76.45  ? 260 GLN E N     1 
ATOM   1447 C CA    . GLN D 4 31 ? 12.797  25.621  3.987   1.00 80.89  ? 260 GLN E CA    1 
ATOM   1448 C C     . GLN D 4 31 ? 13.698  25.819  2.764   1.00 76.67  ? 260 GLN E C     1 
ATOM   1449 O O     . GLN D 4 31 ? 13.286  26.436  1.778   1.00 77.20  ? 260 GLN E O     1 
ATOM   1450 C CB    . GLN D 4 31 ? 13.068  26.587  5.154   1.00 88.75  ? 260 GLN E CB    1 
ATOM   1451 C CG    . GLN D 4 31 ? 14.525  26.679  5.630   1.00 102.91 ? 260 GLN E CG    1 
ATOM   1452 C CD    . GLN D 4 31 ? 14.899  25.854  6.857   1.00 102.47 ? 260 GLN E CD    1 
ATOM   1453 O OE1   . GLN D 4 31 ? 14.387  24.751  7.098   1.00 107.95 ? 260 GLN E OE1   1 
ATOM   1454 N NE2   . GLN D 4 31 ? 15.821  26.384  7.651   1.00 95.04  ? 260 GLN E NE2   1 
ATOM   1455 N N     . ASP D 4 32 ? 14.924  25.283  2.812   1.00 72.68  ? 261 ASP E N     1 
ATOM   1456 C CA    . ASP D 4 32 ? 15.861  25.492  1.718   1.00 72.35  ? 261 ASP E CA    1 
ATOM   1457 C C     . ASP D 4 32 ? 15.287  24.890  0.434   1.00 67.93  ? 261 ASP E C     1 
ATOM   1458 O O     . ASP D 4 32 ? 15.368  25.476  -0.656  1.00 69.11  ? 261 ASP E O     1 
ATOM   1459 C CB    . ASP D 4 32 ? 17.231  24.934  2.065   1.00 79.47  ? 261 ASP E CB    1 
ATOM   1460 C CG    . ASP D 4 32 ? 18.016  25.655  3.152   1.00 83.33  ? 261 ASP E CG    1 
ATOM   1461 O OD1   . ASP D 4 32 ? 17.737  26.839  3.396   1.00 85.65  ? 261 ASP E OD1   1 
ATOM   1462 O OD2   . ASP D 4 32 ? 18.892  25.009  3.772   1.00 90.65  ? 261 ASP E OD2   1 
ATOM   1463 N N     . ARG D 4 33 ? 14.652  23.720  0.570   1.00 66.38  ? 262 ARG E N     1 
ATOM   1464 C CA    . ARG D 4 33 ? 14.093  23.027  -0.580  1.00 60.24  ? 262 ARG E CA    1 
ATOM   1465 C C     . ARG D 4 33 ? 12.955  23.847  -1.187  1.00 70.44  ? 262 ARG E C     1 
ATOM   1466 O O     . ARG D 4 33 ? 12.863  23.961  -2.413  1.00 66.08  ? 262 ARG E O     1 
ATOM   1467 C CB    . ARG D 4 33 ? 13.687  21.601  -0.205  1.00 63.30  ? 262 ARG E CB    1 
ATOM   1468 C CG    . ARG D 4 33 ? 13.527  20.635  -1.362  1.00 65.80  ? 262 ARG E CG    1 
ATOM   1469 C CD    . ARG D 4 33 ? 13.404  19.215  -0.834  1.00 75.90  ? 262 ARG E CD    1 
ATOM   1470 N NE    . ARG D 4 33 ? 12.079  19.056  -0.229  1.00 68.92  ? 262 ARG E NE    1 
ATOM   1471 C CZ    . ARG D 4 33 ? 11.821  18.724  1.013   1.00 74.64  ? 262 ARG E CZ    1 
ATOM   1472 N NH1   . ARG D 4 33 ? 10.558  18.679  1.394   1.00 68.20  ? 262 ARG E NH1   1 
ATOM   1473 N NH2   . ARG D 4 33 ? 12.799  18.476  1.866   1.00 75.14  ? 262 ARG E NH2   1 
ATOM   1474 N N     . MET D 4 34 ? 12.120  24.471  -0.337  1.00 77.98  ? 263 MET E N     1 
ATOM   1475 C CA    . MET D 4 34 ? 11.021  25.292  -0.832  1.00 81.23  ? 263 MET E CA    1 
ATOM   1476 C C     . MET D 4 34 ? 11.581  26.509  -1.577  1.00 78.88  ? 263 MET E C     1 
ATOM   1477 O O     . MET D 4 34 ? 11.170  26.831  -2.691  1.00 78.85  ? 263 MET E O     1 
ATOM   1478 C CB    . MET D 4 34 ? 10.096  25.747  0.306   1.00 93.01  ? 263 MET E CB    1 
ATOM   1479 C CG    . MET D 4 34 ? 9.153   24.673  0.815   1.00 98.05  ? 263 MET E CG    1 
ATOM   1480 S SD    . MET D 4 34 ? 7.984   25.282  2.048   1.00 99.68  ? 263 MET E SD    1 
ATOM   1481 C CE    . MET D 4 34 ? 6.694   24.099  1.639   1.00 92.68  ? 263 MET E CE    1 
ATOM   1482 N N     . ASP D 4 35 ? 12.540  27.192  -0.965  1.00 76.86  ? 264 ASP E N     1 
ATOM   1483 C CA    . ASP D 4 35 ? 13.130  28.360  -1.606  1.00 82.05  ? 264 ASP E CA    1 
ATOM   1484 C C     . ASP D 4 35 ? 13.659  27.990  -2.986  1.00 81.16  ? 264 ASP E C     1 
ATOM   1485 O O     . ASP D 4 35 ? 13.417  28.691  -3.968  1.00 79.30  ? 264 ASP E O     1 
ATOM   1486 C CB    . ASP D 4 35 ? 14.264  28.920  -0.768  1.00 84.89  ? 264 ASP E CB    1 
ATOM   1487 C CG    . ASP D 4 35 ? 13.799  29.394  0.596   1.00 89.96  ? 264 ASP E CG    1 
ATOM   1488 O OD1   . ASP D 4 35 ? 12.580  29.629  0.714   1.00 81.46  ? 264 ASP E OD1   1 
ATOM   1489 O OD2   . ASP D 4 35 ? 14.641  29.469  1.516   1.00 94.05  ? 264 ASP E OD2   1 
ATOM   1490 N N     . LEU D 4 36 ? 14.395  26.879  -3.058  1.00 68.43  ? 265 LEU E N     1 
ATOM   1491 C CA    . LEU D 4 36 ? 15.099  26.609  -4.288  1.00 65.64  ? 265 LEU E CA    1 
ATOM   1492 C C     . LEU D 4 36 ? 14.077  26.258  -5.369  1.00 61.55  ? 265 LEU E C     1 
ATOM   1493 O O     . LEU D 4 36 ? 14.209  26.668  -6.514  1.00 69.99  ? 265 LEU E O     1 
ATOM   1494 C CB    . LEU D 4 36 ? 16.153  25.540  -4.016  1.00 66.74  ? 265 LEU E CB    1 
ATOM   1495 C CG    . LEU D 4 36 ? 16.908  25.029  -5.238  1.00 63.14  ? 265 LEU E CG    1 
ATOM   1496 C CD1   . LEU D 4 36 ? 17.826  26.104  -5.798  1.00 64.26  ? 265 LEU E CD1   1 
ATOM   1497 C CD2   . LEU D 4 36 ? 17.669  23.790  -4.827  1.00 66.92  ? 265 LEU E CD2   1 
ATOM   1498 N N     . ALA D 4 37 ? 13.002  25.565  -5.003  1.00 58.39  ? 266 ALA E N     1 
ATOM   1499 C CA    . ALA D 4 37 ? 11.989  25.229  -5.981  1.00 59.70  ? 266 ALA E CA    1 
ATOM   1500 C C     . ALA D 4 37 ? 11.397  26.518  -6.512  1.00 55.75  ? 266 ALA E C     1 
ATOM   1501 O O     . ALA D 4 37 ? 11.170  26.677  -7.712  1.00 58.19  ? 266 ALA E O     1 
ATOM   1502 C CB    . ALA D 4 37 ? 10.918  24.326  -5.380  1.00 67.24  ? 266 ALA E CB    1 
ATOM   1503 N N     . ALA D 4 38 ? 11.135  27.429  -5.585  1.00 63.97  ? 267 ALA E N     1 
ATOM   1504 C CA    . ALA D 4 38 ? 10.495  28.687  -5.931  1.00 69.34  ? 267 ALA E CA    1 
ATOM   1505 C C     . ALA D 4 38 ? 11.455  29.503  -6.786  1.00 64.96  ? 267 ALA E C     1 
ATOM   1506 O O     . ALA D 4 38 ? 11.049  30.021  -7.819  1.00 64.67  ? 267 ALA E O     1 
ATOM   1507 C CB    . ALA D 4 38 ? 10.055  29.423  -4.686  1.00 68.92  ? 267 ALA E CB    1 
ATOM   1508 N N     . ALA D 4 39 ? 12.740  29.494  -6.404  1.00 71.48  ? 268 ALA E N     1 
ATOM   1509 C CA    . ALA D 4 39 ? 13.803  30.140  -7.171  1.00 73.28  ? 268 ALA E CA    1 
ATOM   1510 C C     . ALA D 4 39 ? 13.781  29.680  -8.630  1.00 72.73  ? 268 ALA E C     1 
ATOM   1511 O O     . ALA D 4 39 ? 13.902  30.504  -9.538  1.00 71.74  ? 268 ALA E O     1 
ATOM   1512 C CB    . ALA D 4 39 ? 15.140  29.839  -6.535  1.00 69.36  ? 268 ALA E CB    1 
ATOM   1513 N N     . LEU D 4 40 ? 13.568  28.371  -8.831  1.00 60.90  ? 269 LEU E N     1 
ATOM   1514 C CA    . LEU D 4 40 ? 13.733  27.726  -10.122 1.00 64.38  ? 269 LEU E CA    1 
ATOM   1515 C C     . LEU D 4 40 ? 12.411  27.513  -10.859 1.00 71.47  ? 269 LEU E C     1 
ATOM   1516 O O     . LEU D 4 40 ? 12.413  26.973  -11.966 1.00 67.75  ? 269 LEU E O     1 
ATOM   1517 C CB    . LEU D 4 40 ? 14.427  26.398  -9.838  1.00 59.40  ? 269 LEU E CB    1 
ATOM   1518 C CG    . LEU D 4 40 ? 15.824  26.522  -9.216  1.00 63.24  ? 269 LEU E CG    1 
ATOM   1519 C CD1   . LEU D 4 40 ? 16.597  25.191  -9.094  1.00 57.99  ? 269 LEU E CD1   1 
ATOM   1520 C CD2   . LEU D 4 40 ? 16.627  27.555  -10.011 1.00 62.57  ? 269 LEU E CD2   1 
ATOM   1521 N N     . ASN D 4 41 ? 11.293  27.910  -10.236 1.00 68.52  ? 270 ASN E N     1 
ATOM   1522 C CA    . ASN D 4 41 ? 9.967   27.717  -10.796 1.00 65.45  ? 270 ASN E CA    1 
ATOM   1523 C C     . ASN D 4 41 ? 9.691   26.222  -10.946 1.00 57.98  ? 270 ASN E C     1 
ATOM   1524 O O     . ASN D 4 41 ? 9.135   25.780  -11.943 1.00 59.41  ? 270 ASN E O     1 
ATOM   1525 C CB    . ASN D 4 41 ? 9.768   28.539  -12.063 1.00 76.16  ? 270 ASN E CB    1 
ATOM   1526 C CG    . ASN D 4 41 ? 8.447   28.227  -12.730 1.00 87.71  ? 270 ASN E CG    1 
ATOM   1527 O OD1   . ASN D 4 41 ? 7.430   28.067  -12.046 1.00 94.21  ? 270 ASN E OD1   1 
ATOM   1528 N ND2   . ASN D 4 41 ? 8.438   28.092  -14.050 1.00 91.37  ? 270 ASN E ND2   1 
ATOM   1529 N N     . LEU D 4 42 ? 10.081  25.446  -9.931  1.00 61.17  ? 271 LEU E N     1 
ATOM   1530 C CA    . LEU D 4 42 ? 9.829   24.010  -9.871  1.00 57.45  ? 271 LEU E CA    1 
ATOM   1531 C C     . LEU D 4 42 ? 8.949   23.692  -8.662  1.00 61.72  ? 271 LEU E C     1 
ATOM   1532 O O     . LEU D 4 42 ? 8.815   24.520  -7.748  1.00 55.10  ? 271 LEU E O     1 
ATOM   1533 C CB    . LEU D 4 42 ? 11.180  23.318  -9.713  1.00 63.07  ? 271 LEU E CB    1 
ATOM   1534 C CG    . LEU D 4 42 ? 12.116  23.365  -10.924 1.00 68.17  ? 271 LEU E CG    1 
ATOM   1535 C CD1   . LEU D 4 42 ? 13.533  22.988  -10.534 1.00 63.35  ? 271 LEU E CD1   1 
ATOM   1536 C CD2   . LEU D 4 42 ? 11.581  22.433  -11.984 1.00 64.92  ? 271 LEU E CD2   1 
ATOM   1537 N N     . THR D 4 43 ? 8.404   22.466  -8.626  1.00 55.29  ? 272 THR E N     1 
ATOM   1538 C CA    . THR D 4 43 ? 7.670   22.021  -7.444  1.00 53.23  ? 272 THR E CA    1 
ATOM   1539 C C     . THR D 4 43 ? 8.677   21.518  -6.426  1.00 55.37  ? 272 THR E C     1 
ATOM   1540 O O     . THR D 4 43 ? 9.766   21.044  -6.737  1.00 57.74  ? 272 THR E O     1 
ATOM   1541 C CB    . THR D 4 43 ? 6.668   20.902  -7.730  1.00 49.84  ? 272 THR E CB    1 
ATOM   1542 O OG1   . THR D 4 43 ? 7.455   19.745  -8.027  1.00 45.67  ? 272 THR E OG1   1 
ATOM   1543 C CG2   . THR D 4 43 ? 5.662   21.267  -8.804  1.00 48.20  ? 272 THR E CG2   1 
ATOM   1544 N N     . ASP D 4 44 ? 8.265   21.570  -5.186  1.00 55.46  ? 273 ASP E N     1 
ATOM   1545 C CA    . ASP D 4 44 ? 9.088   21.039  -4.123  1.00 61.36  ? 273 ASP E CA    1 
ATOM   1546 C C     . ASP D 4 44 ? 9.502   19.598  -4.430  1.00 51.18  ? 273 ASP E C     1 
ATOM   1547 O O     . ASP D 4 44 ? 10.589  19.192  -4.024  1.00 55.66  ? 273 ASP E O     1 
ATOM   1548 C CB    . ASP D 4 44 ? 8.381   21.213  -2.784  1.00 67.86  ? 273 ASP E CB    1 
ATOM   1549 C CG    . ASP D 4 44 ? 9.301   21.056  -1.590  1.00 86.72  ? 273 ASP E CG    1 
ATOM   1550 O OD1   . ASP D 4 44 ? 10.084  21.999  -1.346  1.00 100.62 ? 273 ASP E OD1   1 
ATOM   1551 O OD2   . ASP D 4 44 ? 9.266   19.974  -0.957  1.00 87.34  ? 273 ASP E OD2   1 
ATOM   1552 N N     . THR D 4 45 ? 8.601   18.808  -5.038  1.00 50.62  ? 274 THR E N     1 
ATOM   1553 C CA    . THR D 4 45 ? 8.808   17.378  -5.270  1.00 53.67  ? 274 THR E CA    1 
ATOM   1554 C C     . THR D 4 45 ? 9.881   17.160  -6.351  1.00 51.21  ? 274 THR E C     1 
ATOM   1555 O O     . THR D 4 45 ? 10.777  16.315  -6.212  1.00 51.13  ? 274 THR E O     1 
ATOM   1556 C CB    . THR D 4 45 ? 7.479   16.748  -5.715  1.00 56.19  ? 274 THR E CB    1 
ATOM   1557 O OG1   . THR D 4 45 ? 6.533   16.844  -4.658  1.00 58.15  ? 274 THR E OG1   1 
ATOM   1558 C CG2   . THR D 4 45 ? 7.596   15.280  -6.095  1.00 50.92  ? 274 THR E CG2   1 
ATOM   1559 N N     . GLN D 4 46 ? 9.773   17.943  -7.434  1.00 50.84  ? 275 GLN E N     1 
ATOM   1560 C CA    . GLN D 4 46 ? 10.803  17.968  -8.473  1.00 52.90  ? 275 GLN E CA    1 
ATOM   1561 C C     . GLN D 4 46 ? 12.173  18.163  -7.846  1.00 54.22  ? 275 GLN E C     1 
ATOM   1562 O O     . GLN D 4 46 ? 13.130  17.478  -8.185  1.00 51.44  ? 275 GLN E O     1 
ATOM   1563 C CB    . GLN D 4 46 ? 10.560  19.076  -9.494  1.00 49.36  ? 275 GLN E CB    1 
ATOM   1564 C CG    . GLN D 4 46 ? 9.348   18.793  -10.373 1.00 47.28  ? 275 GLN E CG    1 
ATOM   1565 C CD    . GLN D 4 46 ? 9.090   19.904  -11.373 1.00 58.32  ? 275 GLN E CD    1 
ATOM   1566 O OE1   . GLN D 4 46 ? 9.005   21.093  -11.035 1.00 58.75  ? 275 GLN E OE1   1 
ATOM   1567 N NE2   . GLN D 4 46 ? 8.978   19.517  -12.633 1.00 54.06  ? 275 GLN E NE2   1 
ATOM   1568 N N     . VAL D 4 47 ? 12.249  19.101  -6.907  1.00 52.34  ? 276 VAL E N     1 
ATOM   1569 C CA    . VAL D 4 47 ? 13.513  19.350  -6.259  1.00 48.65  ? 276 VAL E CA    1 
ATOM   1570 C C     . VAL D 4 47 ? 13.856  18.223  -5.295  1.00 55.46  ? 276 VAL E C     1 
ATOM   1571 O O     . VAL D 4 47 ? 15.031  17.907  -5.136  1.00 57.68  ? 276 VAL E O     1 
ATOM   1572 C CB    . VAL D 4 47 ? 13.584  20.699  -5.540  1.00 50.75  ? 276 VAL E CB    1 
ATOM   1573 C CG1   . VAL D 4 47 ? 14.902  20.813  -4.810  1.00 52.18  ? 276 VAL E CG1   1 
ATOM   1574 C CG2   . VAL D 4 47 ? 13.353  21.872  -6.497  1.00 55.85  ? 276 VAL E CG2   1 
ATOM   1575 N N     . LYS D 4 48 ? 12.885  17.660  -4.573  1.00 49.87  ? 277 LYS E N     1 
ATOM   1576 C CA    . LYS D 4 48 ? 13.265  16.632  -3.626  1.00 52.38  ? 277 LYS E CA    1 
ATOM   1577 C C     . LYS D 4 48 ? 13.804  15.426  -4.392  1.00 54.43  ? 277 LYS E C     1 
ATOM   1578 O O     . LYS D 4 48 ? 14.746  14.782  -3.954  1.00 56.03  ? 277 LYS E O     1 
ATOM   1579 C CB    . LYS D 4 48 ? 12.059  16.136  -2.827  1.00 59.31  ? 277 LYS E CB    1 
ATOM   1580 C CG    . LYS D 4 48 ? 12.329  15.311  -1.578  1.00 62.89  ? 277 LYS E CG    1 
ATOM   1581 C CD    . LYS D 4 48 ? 11.147  14.426  -1.162  1.00 62.93  ? 277 LYS E CD    1 
ATOM   1582 C CE    . LYS D 4 48 ? 9.794   14.847  -1.667  1.00 71.70  ? 277 LYS E CE    1 
ATOM   1583 N NZ    . LYS D 4 48 ? 8.743   13.868  -1.358  1.00 84.84  ? 277 LYS E NZ    1 
ATOM   1584 N N     . THR D 4 49 ? 13.146  15.094  -5.500  1.00 60.48  ? 278 THR E N     1 
ATOM   1585 C CA    . THR D 4 49 ? 13.481  13.913  -6.300  1.00 57.71  ? 278 THR E CA    1 
ATOM   1586 C C     . THR D 4 49 ? 14.890  14.068  -6.873  1.00 58.66  ? 278 THR E C     1 
ATOM   1587 O O     . THR D 4 49 ? 15.749  13.208  -6.711  1.00 64.18  ? 278 THR E O     1 
ATOM   1588 C CB    . THR D 4 49 ? 12.445  13.806  -7.418  1.00 56.37  ? 278 THR E CB    1 
ATOM   1589 O OG1   . THR D 4 49 ? 11.183  13.921  -6.758  1.00 57.51  ? 278 THR E OG1   1 
ATOM   1590 C CG2   . THR D 4 49 ? 12.539  12.514  -8.215  1.00 61.88  ? 278 THR E CG2   1 
ATOM   1591 N N     . TRP D 4 50 ? 15.119  15.196  -7.542  1.00 54.32  ? 279 TRP E N     1 
ATOM   1592 C CA    . TRP D 4 50 ? 16.418  15.519  -8.098  1.00 50.03  ? 279 TRP E CA    1 
ATOM   1593 C C     . TRP D 4 50 ? 17.509  15.252  -7.078  1.00 51.90  ? 279 TRP E C     1 
ATOM   1594 O O     . TRP D 4 50 ? 18.338  14.380  -7.276  1.00 55.49  ? 279 TRP E O     1 
ATOM   1595 C CB    . TRP D 4 50 ? 16.431  16.973  -8.568  1.00 49.77  ? 279 TRP E CB    1 
ATOM   1596 C CG    . TRP D 4 50 ? 17.693  17.256  -9.321  1.00 54.85  ? 279 TRP E CG    1 
ATOM   1597 C CD1   . TRP D 4 50 ? 17.868  17.148  -10.669 1.00 57.94  ? 279 TRP E CD1   1 
ATOM   1598 C CD2   . TRP D 4 50 ? 18.951  17.669  -8.765  1.00 59.14  ? 279 TRP E CD2   1 
ATOM   1599 N NE1   . TRP D 4 50 ? 19.147  17.483  -10.983 1.00 55.47  ? 279 TRP E NE1   1 
ATOM   1600 C CE2   . TRP D 4 50 ? 19.842  17.791  -9.846  1.00 57.70  ? 279 TRP E CE2   1 
ATOM   1601 C CE3   . TRP D 4 50 ? 19.408  17.961  -7.472  1.00 71.13  ? 279 TRP E CE3   1 
ATOM   1602 C CZ2   . TRP D 4 50 ? 21.164  18.188  -9.672  1.00 56.74  ? 279 TRP E CZ2   1 
ATOM   1603 C CZ3   . TRP D 4 50 ? 20.713  18.378  -7.304  1.00 65.96  ? 279 TRP E CZ3   1 
ATOM   1604 C CH2   . TRP D 4 50 ? 21.582  18.470  -8.393  1.00 61.41  ? 279 TRP E CH2   1 
ATOM   1605 N N     . TYR D 4 51 ? 17.387  15.898  -5.914  1.00 54.86  ? 280 TYR E N     1 
ATOM   1606 C CA    . TYR D 4 51 ? 18.341  15.770  -4.829  1.00 51.79  ? 280 TYR E CA    1 
ATOM   1607 C C     . TYR D 4 51 ? 18.473  14.310  -4.458  1.00 47.24  ? 280 TYR E C     1 
ATOM   1608 O O     . TYR D 4 51 ? 19.563  13.822  -4.206  1.00 53.45  ? 280 TYR E O     1 
ATOM   1609 C CB    . TYR D 4 51 ? 18.001  16.587  -3.578  1.00 56.94  ? 280 TYR E CB    1 
ATOM   1610 C CG    . TYR D 4 51 ? 18.884  17.806  -3.380  1.00 51.26  ? 280 TYR E CG    1 
ATOM   1611 C CD1   . TYR D 4 51 ? 20.048  17.711  -2.637  1.00 57.73  ? 280 TYR E CD1   1 
ATOM   1612 C CD2   . TYR D 4 51 ? 18.569  19.042  -3.931  1.00 51.36  ? 280 TYR E CD2   1 
ATOM   1613 C CE1   . TYR D 4 51 ? 20.888  18.802  -2.453  1.00 58.44  ? 280 TYR E CE1   1 
ATOM   1614 C CE2   . TYR D 4 51 ? 19.379  20.154  -3.711  1.00 52.03  ? 280 TYR E CE2   1 
ATOM   1615 C CZ    . TYR D 4 51 ? 20.551  20.038  -2.980  1.00 57.04  ? 280 TYR E CZ    1 
ATOM   1616 O OH    . TYR D 4 51 ? 21.403  21.108  -2.775  1.00 61.08  ? 280 TYR E OH    1 
ATOM   1617 N N     . GLN D 4 52 ? 17.374  13.589  -4.428  1.00 49.84  ? 281 GLN E N     1 
ATOM   1618 C CA    . GLN D 4 52 ? 17.494  12.201  -3.996  1.00 56.08  ? 281 GLN E CA    1 
ATOM   1619 C C     . GLN D 4 52 ? 18.293  11.430  -5.048  1.00 55.05  ? 281 GLN E C     1 
ATOM   1620 O O     . GLN D 4 52 ? 19.262  10.771  -4.717  1.00 52.93  ? 281 GLN E O     1 
ATOM   1621 C CB    . GLN D 4 52 ? 16.153  11.525  -3.698  1.00 54.27  ? 281 GLN E CB    1 
ATOM   1622 C CG    . GLN D 4 52 ? 16.297  10.170  -3.008  1.00 55.79  ? 281 GLN E CG    1 
ATOM   1623 C CD    . GLN D 4 52 ? 17.141  10.202  -1.750  1.00 63.19  ? 281 GLN E CD    1 
ATOM   1624 O OE1   . GLN D 4 52 ? 16.907  10.990  -0.820  1.00 60.73  ? 281 GLN E OE1   1 
ATOM   1625 N NE2   . GLN D 4 52 ? 18.131  9.318   -1.692  1.00 63.50  ? 281 GLN E NE2   1 
ATOM   1626 N N     . ASN D 4 53 ? 17.879  11.531  -6.315  1.00 58.50  ? 282 ASN E N     1 
ATOM   1627 C CA    . ASN D 4 53 ? 18.601  10.919  -7.420  1.00 56.73  ? 282 ASN E CA    1 
ATOM   1628 C C     . ASN D 4 53 ? 20.073  11.359  -7.364  1.00 61.41  ? 282 ASN E C     1 
ATOM   1629 O O     . ASN D 4 53 ? 20.989  10.547  -7.482  1.00 58.27  ? 282 ASN E O     1 
ATOM   1630 C CB    . ASN D 4 53 ? 17.847  11.172  -8.722  1.00 51.44  ? 282 ASN E CB    1 
ATOM   1631 C CG    . ASN D 4 53 ? 16.642  10.272  -8.835  1.00 49.38  ? 282 ASN E CG    1 
ATOM   1632 O OD1   . ASN D 4 53 ? 16.723  9.123   -8.411  1.00 46.14  ? 282 ASN E OD1   1 
ATOM   1633 N ND2   . ASN D 4 53 ? 15.543  10.707  -9.442  1.00 48.94  ? 282 ASN E ND2   1 
ATOM   1634 N N     . ARG D 4 54 ? 20.316  12.624  -7.029  1.00 54.69  ? 283 ARG E N     1 
ATOM   1635 C CA    . ARG D 4 54 ? 21.651  13.162  -7.138  1.00 56.70  ? 283 ARG E CA    1 
ATOM   1636 C C     . ARG D 4 54 ? 22.566  12.530  -6.094  1.00 63.82  ? 283 ARG E C     1 
ATOM   1637 O O     . ARG D 4 54 ? 23.752  12.309  -6.349  1.00 62.23  ? 283 ARG E O     1 
ATOM   1638 C CB    . ARG D 4 54 ? 21.595  14.689  -7.071  1.00 59.04  ? 283 ARG E CB    1 
ATOM   1639 C CG    . ARG D 4 54 ? 22.966  15.300  -7.329  1.00 64.68  ? 283 ARG E CG    1 
ATOM   1640 C CD    . ARG D 4 54 ? 23.440  15.200  -8.773  1.00 63.93  ? 283 ARG E CD    1 
ATOM   1641 N NE    . ARG D 4 54 ? 24.849  15.608  -8.844  1.00 71.71  ? 283 ARG E NE    1 
ATOM   1642 C CZ    . ARG D 4 54 ? 25.903  14.806  -8.679  1.00 80.49  ? 283 ARG E CZ    1 
ATOM   1643 N NH1   . ARG D 4 54 ? 27.109  15.331  -8.727  1.00 80.18  ? 283 ARG E NH1   1 
ATOM   1644 N NH2   . ARG D 4 54 ? 25.782  13.492  -8.482  1.00 85.80  ? 283 ARG E NH2   1 
ATOM   1645 N N     . ARG D 4 55 ? 22.036  12.266  -4.899  1.00 61.63  ? 284 ARG E N     1 
ATOM   1646 C CA    . ARG D 4 55 ? 22.867  11.712  -3.843  1.00 59.91  ? 284 ARG E CA    1 
ATOM   1647 C C     . ARG D 4 55 ? 23.246  10.278  -4.207  1.00 58.93  ? 284 ARG E C     1 
ATOM   1648 O O     . ARG D 4 55 ? 24.291  9.788   -3.797  1.00 71.30  ? 284 ARG E O     1 
ATOM   1649 C CB    . ARG D 4 55 ? 22.171  11.717  -2.474  1.00 67.14  ? 284 ARG E CB    1 
ATOM   1650 C CG    . ARG D 4 55 ? 22.036  13.092  -1.837  1.00 67.53  ? 284 ARG E CG    1 
ATOM   1651 C CD    . ARG D 4 55 ? 21.634  13.011  -0.380  1.00 70.66  ? 284 ARG E CD    1 
ATOM   1652 N NE    . ARG D 4 55 ? 20.212  12.697  -0.250  1.00 65.92  ? 284 ARG E NE    1 
ATOM   1653 C CZ    . ARG D 4 55 ? 19.253  13.593  -0.398  1.00 67.16  ? 284 ARG E CZ    1 
ATOM   1654 N NH1   . ARG D 4 55 ? 19.498  14.908  -0.371  1.00 57.36  ? 284 ARG E NH1   1 
ATOM   1655 N NH2   . ARG D 4 55 ? 18.017  13.154  -0.509  1.00 62.46  ? 284 ARG E NH2   1 
ATOM   1656 N N     . THR D 4 56 ? 22.381  9.612   -4.967  1.00 59.81  ? 285 THR E N     1 
ATOM   1657 C CA    . THR D 4 56 ? 22.612  8.244   -5.400  1.00 66.55  ? 285 THR E CA    1 
ATOM   1658 C C     . THR D 4 56 ? 23.801  8.239   -6.344  1.00 70.30  ? 285 THR E C     1 
ATOM   1659 O O     . THR D 4 56 ? 24.748  7.486   -6.168  1.00 69.87  ? 285 THR E O     1 
ATOM   1660 C CB    . THR D 4 56 ? 21.376  7.715   -6.125  1.00 60.46  ? 285 THR E CB    1 
ATOM   1661 O OG1   . THR D 4 56 ? 20.383  7.734   -5.105  1.00 67.95  ? 285 THR E OG1   1 
ATOM   1662 C CG2   . THR D 4 56 ? 21.598  6.332   -6.711  1.00 57.13  ? 285 THR E CG2   1 
ATOM   1663 N N     . LYS D 4 57 ? 23.695  9.087   -7.365  1.00 76.08  ? 286 LYS E N     1 
ATOM   1664 C CA    . LYS D 4 57 ? 24.740  9.202   -8.352  1.00 77.55  ? 286 LYS E CA    1 
ATOM   1665 C C     . LYS D 4 57 ? 26.051  9.482   -7.621  1.00 79.15  ? 286 LYS E C     1 
ATOM   1666 O O     . LYS D 4 57 ? 27.065  8.785   -7.827  1.00 66.28  ? 286 LYS E O     1 
ATOM   1667 C CB    . LYS D 4 57 ? 24.284  10.287  -9.325  1.00 75.80  ? 286 LYS E CB    1 
ATOM   1668 C CG    . LYS D 4 57 ? 25.230  10.464  -10.497 1.00 83.72  ? 286 LYS E CG    1 
ATOM   1669 C CD    . LYS D 4 57 ? 24.930  11.714  -11.312 1.00 77.28  ? 286 LYS E CD    1 
ATOM   1670 C CE    . LYS D 4 57 ? 26.086  12.005  -12.210 1.00 78.59  ? 286 LYS E CE    1 
ATOM   1671 N NZ    . LYS D 4 57 ? 25.694  13.120  -13.065 1.00 76.97  ? 286 LYS E NZ    1 
ATOM   1672 N N     . TRP D 4 58 ? 25.990  10.464  -6.707  1.00 71.65  ? 287 TRP E N     1 
ATOM   1673 C CA    . TRP D 4 58 ? 27.190  10.888  -6.007  1.00 78.74  ? 287 TRP E CA    1 
ATOM   1674 C C     . TRP D 4 58 ? 27.769  9.747   -5.164  1.00 81.61  ? 287 TRP E C     1 
ATOM   1675 O O     . TRP D 4 58 ? 28.983  9.627   -5.039  1.00 82.80  ? 287 TRP E O     1 
ATOM   1676 C CB    . TRP D 4 58 ? 26.930  12.150  -5.177  1.00 80.29  ? 287 TRP E CB    1 
ATOM   1677 C CG    . TRP D 4 58 ? 28.092  12.520  -4.302  1.00 86.87  ? 287 TRP E CG    1 
ATOM   1678 C CD1   . TRP D 4 58 ? 29.296  13.004  -4.714  1.00 97.60  ? 287 TRP E CD1   1 
ATOM   1679 C CD2   . TRP D 4 58 ? 28.160  12.413  -2.864  1.00 99.44  ? 287 TRP E CD2   1 
ATOM   1680 N NE1   . TRP D 4 58 ? 30.110  13.210  -3.632  1.00 110.39 ? 287 TRP E NE1   1 
ATOM   1681 C CE2   . TRP D 4 58 ? 29.445  12.858  -2.485  1.00 108.75 ? 287 TRP E CE2   1 
ATOM   1682 C CE3   . TRP D 4 58 ? 27.271  11.993  -1.868  1.00 105.87 ? 287 TRP E CE3   1 
ATOM   1683 C CZ2   . TRP D 4 58 ? 29.857  12.889  -1.154  1.00 120.71 ? 287 TRP E CZ2   1 
ATOM   1684 C CZ3   . TRP D 4 58 ? 27.684  12.011  -0.553  1.00 113.34 ? 287 TRP E CZ3   1 
ATOM   1685 C CH2   . TRP D 4 58 ? 28.963  12.448  -0.204  1.00 119.89 ? 287 TRP E CH2   1 
ATOM   1686 N N     . LYS D 4 59 ? 26.928  8.868   -4.619  1.00 82.18  ? 288 LYS E N     1 
ATOM   1687 C CA    . LYS D 4 59 ? 27.451  7.686   -3.945  1.00 92.88  ? 288 LYS E CA    1 
ATOM   1688 C C     . LYS D 4 59 ? 28.202  6.790   -4.929  1.00 89.02  ? 288 LYS E C     1 
ATOM   1689 O O     . LYS D 4 59 ? 29.231  6.246   -4.549  1.00 80.98  ? 288 LYS E O     1 
ATOM   1690 C CB    . LYS D 4 59 ? 26.382  6.959   -3.126  1.00 98.72  ? 288 LYS E CB    1 
ATOM   1691 C CG    . LYS D 4 59 ? 26.094  7.711   -1.829  1.00 111.55 ? 288 LYS E CG    1 
ATOM   1692 C CD    . LYS D 4 59 ? 24.957  7.141   -0.993  1.00 122.61 ? 288 LYS E CD    1 
ATOM   1693 C CE    . LYS D 4 59 ? 24.215  8.204   -0.232  1.00 125.05 ? 288 LYS E CE    1 
ATOM   1694 N NZ    . LYS D 4 59 ? 23.029  7.673   0.448   1.00 121.84 ? 288 LYS E NZ    1 
ATOM   1695 N N     . ARG D 4 60 ? 27.736  6.701   -6.188  1.00 88.30  ? 289 ARG E N     1 
ATOM   1696 C CA    . ARG D 4 60 ? 28.424  5.948   -7.231  1.00 96.41  ? 289 ARG E CA    1 
ATOM   1697 C C     . ARG D 4 60 ? 29.780  6.568   -7.573  1.00 98.98  ? 289 ARG E C     1 
ATOM   1698 O O     . ARG D 4 60 ? 30.686  5.846   -7.971  1.00 97.55  ? 289 ARG E O     1 
ATOM   1699 C CB    . ARG D 4 60 ? 27.620  5.816   -8.531  1.00 100.42 ? 289 ARG E CB    1 
ATOM   1700 C CG    . ARG D 4 60 ? 26.533  4.750   -8.528  1.00 103.91 ? 289 ARG E CG    1 
ATOM   1701 C CD    . ARG D 4 60 ? 25.993  4.478   -9.929  1.00 109.70 ? 289 ARG E CD    1 
ATOM   1702 N NE    . ARG D 4 60 ? 25.433  5.687   -10.550 1.00 110.36 ? 289 ARG E NE    1 
ATOM   1703 C CZ    . ARG D 4 60 ? 24.825  5.775   -11.739 1.00 113.40 ? 289 ARG E CZ    1 
ATOM   1704 N NH1   . ARG D 4 60 ? 24.561  4.697   -12.465 1.00 111.31 ? 289 ARG E NH1   1 
ATOM   1705 N NH2   . ARG D 4 60 ? 24.464  6.964   -12.198 1.00 110.78 ? 289 ARG E NH2   1 
ATOM   1706 N N     . GLN D 4 61 ? 29.918  7.895   -7.426  1.00 99.61  ? 290 GLN E N     1 
ATOM   1707 C CA    . GLN D 4 61 ? 31.183  8.580   -7.667  1.00 104.45 ? 290 GLN E CA    1 
ATOM   1708 C C     . GLN D 4 61 ? 32.135  8.358   -6.492  1.00 99.85  ? 290 GLN E C     1 
ATOM   1709 O O     . GLN D 4 61 ? 33.247  7.895   -6.714  1.00 104.23 ? 290 GLN E O     1 
ATOM   1710 C CB    . GLN D 4 61 ? 31.058  10.093  -7.903  1.00 115.47 ? 290 GLN E CB    1 
ATOM   1711 C CG    . GLN D 4 61 ? 31.071  10.557  -9.363  1.00 116.28 ? 290 GLN E CG    1 
ATOM   1712 C CD    . GLN D 4 61 ? 29.731  10.480  -10.074 1.00 109.59 ? 290 GLN E CD    1 
ATOM   1713 O OE1   . GLN D 4 61 ? 29.084  11.498  -10.372 1.00 94.03  ? 290 GLN E OE1   1 
ATOM   1714 N NE2   . GLN D 4 61 ? 29.308  9.259   -10.372 1.00 112.22 ? 290 GLN E NE2   1 
ATOM   1715 N N     . THR D 4 62 ? 31.709  8.704   -5.262  1.00 96.98  ? 291 THR E N     1 
ATOM   1716 C CA    . THR D 4 62 ? 32.542  8.542   -4.070  1.00 106.21 ? 291 THR E CA    1 
ATOM   1717 C C     . THR D 4 62 ? 33.028  7.096   -3.994  1.00 115.01 ? 291 THR E C     1 
ATOM   1718 O O     . THR D 4 62 ? 34.229  6.853   -3.905  1.00 123.64 ? 291 THR E O     1 
ATOM   1719 C CB    . THR D 4 62 ? 31.820  8.908   -2.769  1.00 106.40 ? 291 THR E CB    1 
ATOM   1720 O OG1   . THR D 4 62 ? 31.152  10.156  -2.926  1.00 108.77 ? 291 THR E OG1   1 
ATOM   1721 C CG2   . THR D 4 62 ? 32.786  9.005   -1.599  1.00 108.83 ? 291 THR E CG2   1 
ATOM   1722 N N     . ALA D 4 63 ? 32.067  6.159   -3.987  1.00 113.25 ? 292 ALA E N     1 
ATOM   1723 C CA    . ALA D 4 63 ? 32.309  4.736   -4.167  1.00 113.71 ? 292 ALA E CA    1 
ATOM   1724 C C     . ALA D 4 63 ? 33.808  4.426   -4.276  1.00 112.13 ? 292 ALA E C     1 
ATOM   1725 O O     . ALA D 4 63 ? 34.399  4.013   -3.253  1.00 111.64 ? 292 ALA E O     1 
ATOM   1726 C CB    . ALA D 4 63 ? 31.560  4.275   -5.401  1.00 111.94 ? 292 ALA E CB    1 
HETATM 1727 O O     . HOH E 5 .  ? 2.754   -0.906  16.656  1.00 45.51  ? 101 HOH B O     1 
HETATM 1728 O O     . HOH E 5 .  ? 1.044   -1.906  14.861  1.00 65.48  ? 102 HOH B O     1 
HETATM 1729 O O     . HOH F 5 .  ? 13.327  15.254  -10.457 1.00 55.40  ? 101 HOH D O     1 
HETATM 1730 O O     . HOH F 5 .  ? 15.478  13.552  -10.368 1.00 50.66  ? 102 HOH D O     1 
HETATM 1731 O O     . HOH G 5 .  ? -6.968  -9.172  12.153  1.00 54.76  ? 301 HOH A O     1 
HETATM 1732 O O     . HOH G 5 .  ? -6.221  -10.933 14.891  1.00 59.74  ? 302 HOH A O     1 
HETATM 1733 O O     . HOH G 5 .  ? 0.802   -11.078 26.068  1.00 79.99  ? 303 HOH A O     1 
HETATM 1734 O O     . HOH H 5 .  ? 5.923   22.886  -4.591  1.00 56.18  ? 301 HOH E O     1 
HETATM 1735 O O     . HOH H 5 .  ? 12.402  32.063  2.641   1.00 72.65  ? 302 HOH E O     1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    O "O5'" . DC  A 1  ? 1.3435 1.2848 0.9558 -0.0933 0.1218  -0.0505 1   DC  B "O5'" 
2    C "C5'" . DC  A 1  ? 1.2360 1.1474 0.8610 -0.0818 0.1297  -0.0551 1   DC  B "C5'" 
3    C "C4'" . DC  A 1  ? 1.1508 1.0592 0.8100 -0.0508 0.1293  -0.0482 1   DC  B "C4'" 
4    O "O4'" . DC  A 1  ? 1.1217 0.9873 0.7794 -0.0420 0.1451  -0.0530 1   DC  B "O4'" 
5    C "C3'" . DC  A 1  ? 1.0632 0.9986 0.7533 -0.0356 0.1188  -0.0411 1   DC  B "C3'" 
6    O "O3'" . DC  A 1  ? 1.0896 1.0305 0.8016 -0.0142 0.1163  -0.0335 1   DC  B "O3'" 
7    C "C2'" . DC  A 1  ? 1.0765 0.9827 0.7681 -0.0342 0.1280  -0.0473 1   DC  B "C2'" 
8    C "C1'" . DC  A 1  ? 1.0616 0.9295 0.7423 -0.0293 0.1438  -0.0507 1   DC  B "C1'" 
9    N N1    . DC  A 1  ? 0.9999 0.8292 0.6615 -0.0336 0.1606  -0.0565 1   DC  B N1    
10   C C2    . DC  A 1  ? 1.0100 0.8213 0.6860 -0.0133 0.1724  -0.0517 1   DC  B C2    
11   O O2    . DC  A 1  ? 0.9992 0.8300 0.7031 0.0023  0.1667  -0.0445 1   DC  B O2    
12   N N3    . DC  A 1  ? 1.0170 0.7904 0.6730 -0.0117 0.1920  -0.0534 1   DC  B N3    
13   C C4    . DC  A 1  ? 1.1585 0.9030 0.7760 -0.0332 0.2010  -0.0629 1   DC  B C4    
14   N N4    . DC  A 1  ? 1.2117 0.9098 0.8048 -0.0287 0.2248  -0.0635 1   DC  B N4    
15   C C5    . DC  A 1  ? 1.1328 0.8976 0.7338 -0.0605 0.1872  -0.0702 1   DC  B C5    
16   C C6    . DC  A 1  ? 1.0699 0.8811 0.6964 -0.0576 0.1668  -0.0651 1   DC  B C6    
17   P P     . DT  A 2  ? 1.0145 0.9772 0.7506 0.0020  0.1085  -0.0250 2   DT  B P     
18   O OP1   . DT  A 2  ? 1.0388 0.9944 0.7825 0.0176  0.1110  -0.0194 2   DT  B OP1   
19   O OP2   . DT  A 2  ? 1.0312 1.0310 0.7671 -0.0028 0.0993  -0.0186 2   DT  B OP2   
20   O "O5'" . DT  A 2  ? 0.9506 0.8923 0.6987 0.0054  0.1132  -0.0305 2   DT  B "O5'" 
21   C "C5'" . DT  A 2  ? 0.9387 0.8642 0.6978 0.0161  0.1189  -0.0297 2   DT  B "C5'" 
22   C "C4'" . DT  A 2  ? 0.9477 0.8647 0.7177 0.0186  0.1227  -0.0316 2   DT  B "C4'" 
23   O "O4'" . DT  A 2  ? 0.9134 0.8132 0.6681 0.0105  0.1308  -0.0369 2   DT  B "O4'" 
24   C "C3'" . DT  A 2  ? 0.9514 0.8823 0.7333 0.0211  0.1152  -0.0298 2   DT  B "C3'" 
25   O "O3'" . DT  A 2  ? 0.8734 0.8028 0.6700 0.0272  0.1167  -0.0277 2   DT  B "O3'" 
26   C "C2'" . DT  A 2  ? 0.9015 0.8297 0.6730 0.0110  0.1161  -0.0346 2   DT  B "C2'" 
27   C "C1'" . DT  A 2  ? 0.8962 0.7982 0.6570 0.0102  0.1291  -0.0377 2   DT  B "C1'" 
28   N N1    . DT  A 2  ? 0.8756 0.7563 0.6118 -0.0024 0.1380  -0.0441 2   DT  B N1    
29   C C2    . DT  A 2  ? 1.0070 0.8592 0.7364 0.0044  0.1540  -0.0436 2   DT  B C2    
30   O O2    . DT  A 2  ? 1.0141 0.8698 0.7618 0.0203  0.1581  -0.0363 2   DT  B O2    
31   N N3    . DT  A 2  ? 0.9861 0.8067 0.6834 -0.0086 0.1669  -0.0505 2   DT  B N3    
32   C C4    . DT  A 2  ? 1.0204 0.8413 0.6930 -0.0328 0.1628  -0.0588 2   DT  B C4    
33   O O4    . DT  A 2  ? 1.0923 0.8770 0.7296 -0.0477 0.1778  -0.0661 2   DT  B O4    
34   C C5    . DT  A 2  ? 0.9018 0.7669 0.5893 -0.0389 0.1427  -0.0567 2   DT  B C5    
35   C C7    . DT  A 2  ? 0.8932 0.7749 0.5574 -0.0660 0.1365  -0.0619 2   DT  B C7    
36   C C6    . DT  A 2  ? 0.8701 0.7593 0.5876 -0.0210 0.1328  -0.0490 2   DT  B C6    
37   P P     . DA  A 3  ? 0.8509 0.7857 0.6544 0.0311  0.1128  -0.0242 3   DA  B P     
38   O OP1   . DA  A 3  ? 0.8400 0.7687 0.6348 0.0333  0.1149  -0.0220 3   DA  B OP1   
39   O OP2   . DA  A 3  ? 0.9662 0.9092 0.7715 0.0320  0.1073  -0.0238 3   DA  B OP2   
40   O "O5'" . DA  A 3  ? 0.7578 0.6955 0.5735 0.0309  0.1159  -0.0232 3   DA  B "O5'" 
41   C "C5'" . DA  A 3  ? 0.7833 0.7248 0.6045 0.0313  0.1213  -0.0197 3   DA  B "C5'" 
42   C "C4'" . DA  A 3  ? 0.8452 0.7991 0.6793 0.0352  0.1243  -0.0143 3   DA  B "C4'" 
43   O "O4'" . DA  A 3  ? 0.7933 0.7327 0.6204 0.0404  0.1310  -0.0157 3   DA  B "O4'" 
44   C "C3'" . DA  A 3  ? 0.8229 0.7893 0.6654 0.0324  0.1176  -0.0129 3   DA  B "C3'" 
45   O "O3'" . DA  A 3  ? 0.8412 0.8319 0.6976 0.0342  0.1200  -0.0035 3   DA  B "O3'" 
46   C "C2'" . DA  A 3  ? 0.8297 0.7852 0.6681 0.0359  0.1174  -0.0163 3   DA  B "C2'" 
47   C "C1'" . DA  A 3  ? 0.8500 0.7918 0.6811 0.0417  0.1286  -0.0153 3   DA  B "C1'" 
48   N N9    . DA  A 3  ? 0.8850 0.8064 0.6987 0.0372  0.1310  -0.0226 3   DA  B N9    
49   C C8    . DA  A 3  ? 0.9032 0.8245 0.7076 0.0285  0.1235  -0.0287 3   DA  B C8    
50   N N7    . DA  A 3  ? 0.8551 0.7635 0.6420 0.0202  0.1269  -0.0341 3   DA  B N7    
51   C C5    . DA  A 3  ? 0.8040 0.6928 0.5849 0.0253  0.1400  -0.0326 3   DA  B C5    
52   C C6    . DA  A 3  ? 0.8801 0.7397 0.6359 0.0187  0.1527  -0.0373 3   DA  B C6    
53   N N6    . DA  A 3  ? 0.9269 0.7795 0.6605 0.0000  0.1508  -0.0460 3   DA  B N6    
54   N N1    . DA  A 3  ? 0.9908 0.8290 0.7418 0.0314  0.1696  -0.0313 3   DA  B N1    
55   C C2    . DA  A 3  ? 0.9211 0.7799 0.6971 0.0488  0.1698  -0.0196 3   DA  B C2    
56   N N3    . DA  A 3  ? 0.9176 0.8102 0.7187 0.0509  0.1559  -0.0156 3   DA  B N3    
57   C C4    . DA  A 3  ? 0.8334 0.7334 0.6331 0.0386  0.1426  -0.0236 3   DA  B C4    
58   P P     . DA  A 4  ? 0.8736 0.8851 0.7386 0.0285  0.1133  0.0002  4   DA  B P     
59   O OP1   . DA  A 4  ? 0.7792 0.8276 0.6552 0.0210  0.1123  0.0103  4   DA  B OP1   
60   O OP2   . DA  A 4  ? 0.9962 0.9886 0.8491 0.0209  0.1071  -0.0091 4   DA  B OP2   
61   O "O5'" . DA  A 4  ? 0.8400 0.8478 0.7096 0.0421  0.1185  0.0044  4   DA  B "O5'" 
62   C "C5'" . DA  A 4  ? 0.8608 0.8783 0.7372 0.0559  0.1302  0.0160  4   DA  B "C5'" 
63   C "C4'" . DA  A 4  ? 0.8511 0.8567 0.7248 0.0688  0.1386  0.0205  4   DA  B "C4'" 
64   O "O4'" . DA  A 4  ? 0.7945 0.7598 0.6480 0.0659  0.1422  0.0077  4   DA  B "O4'" 
65   C "C3'" . DA  A 4  ? 0.8023 0.8255 0.6843 0.0663  0.1305  0.0236  4   DA  B "C3'" 
66   O "O3'" . DA  A 4  ? 0.7905 0.8292 0.6802 0.0843  0.1423  0.0405  4   DA  B "O3'" 
67   C "C2'" . DA  A 4  ? 0.7872 0.7773 0.6546 0.0601  0.1270  0.0093  4   DA  B "C2'" 
68   C "C1'" . DA  A 4  ? 0.8530 0.8102 0.7031 0.0648  0.1397  0.0047  4   DA  B "C1'" 
69   N N9    . DA  A 4  ? 0.8739 0.8081 0.7081 0.0529  0.1351  -0.0092 4   DA  B N9    
70   C C8    . DA  A 4  ? 0.7492 0.6910 0.5851 0.0427  0.1228  -0.0162 4   DA  B C8    
71   N N7    . DA  A 4  ? 0.7651 0.6936 0.5867 0.0347  0.1214  -0.0244 4   DA  B N7    
72   C C5    . DA  A 4  ? 0.7952 0.7008 0.6012 0.0350  0.1334  -0.0258 4   DA  B C5    
73   C C6    . DA  A 4  ? 0.8388 0.7233 0.6208 0.0225  0.1385  -0.0342 4   DA  B C6    
74   N N6    . DA  A 4  ? 0.7905 0.6867 0.5670 0.0090  0.1287  -0.0403 4   DA  B N6    
75   N N1    . DA  A 4  ? 0.9627 0.8141 0.7231 0.0238  0.1561  -0.0346 4   DA  B N1    
76   C C2    . DA  A 4  ? 0.9096 0.7557 0.6775 0.0425  0.1676  -0.0239 4   DA  B C2    
77   N N3    . DA  A 4  ? 0.8849 0.7613 0.6804 0.0564  0.1619  -0.0128 4   DA  B N3    
78   C C4    . DA  A 4  ? 0.8585 0.7622 0.6705 0.0488  0.1441  -0.0161 4   DA  B C4    
79   P P     . DA  A 5  ? 0.9325 0.9881 0.8291 0.0901  0.1405  0.0496  5   DA  B P     
80   O OP1   . DA  A 5  ? 0.9487 1.0492 0.8622 0.1070  0.1486  0.0741  5   DA  B OP1   
81   O OP2   . DA  A 5  ? 0.9189 0.9830 0.8171 0.0694  0.1225  0.0385  5   DA  B OP2   
82   O "O5'" . DA  A 5  ? 0.8761 0.8776 0.7499 0.0982  0.1540  0.0411  5   DA  B "O5'" 
83   C "C5'" . DA  A 5  ? 0.9798 0.9585 0.8415 0.1198  0.1780  0.0525  5   DA  B "C5'" 
84   C "C4'" . DA  A 5  ? 0.9615 0.8909 0.7969 0.1205  0.1894  0.0442  5   DA  B "C4'" 
85   O "O4'" . DA  A 5  ? 0.8946 0.7970 0.7147 0.0978  0.1798  0.0221  5   DA  B "O4'" 
86   C "C3'" . DA  A 5  ? 1.0155 0.9604 0.8591 0.1227  0.1832  0.0493  5   DA  B "C3'" 
87   O "O3'" . DA  A 5  ? 1.0238 0.9328 0.8460 0.1407  0.2072  0.0579  5   DA  B "O3'" 
88   C "C2'" . DA  A 5  ? 0.9526 0.8848 0.7906 0.0986  0.1660  0.0282  5   DA  B "C2'" 
89   C "C1'" . DA  A 5  ? 1.0298 0.9223 0.8438 0.0888  0.1736  0.0143  5   DA  B "C1'" 
90   N N9    . DA  A 5  ? 0.9183 0.8128 0.7315 0.0676  0.1569  -0.0019 5   DA  B N9    
91   C C8    . DA  A 5  ? 0.8924 0.8165 0.7239 0.0596  0.1392  -0.0049 5   DA  B C8    
92   N N7    . DA  A 5  ? 0.8559 0.7736 0.6795 0.0457  0.1313  -0.0167 5   DA  B N7    
93   C C5    . DA  A 5  ? 0.7838 0.6703 0.5829 0.0397  0.1425  -0.0230 5   DA  B C5    
94   C C6    . DA  A 5  ? 0.9406 0.8163 0.7213 0.0220  0.1404  -0.0342 5   DA  B C6    
95   N N6    . DA  A 5  ? 0.9353 0.8344 0.7242 0.0135  0.1262  -0.0379 5   DA  B N6    
96   N N1    . DA  A 5  ? 0.9618 0.8025 0.7119 0.0128  0.1552  -0.0399 5   DA  B N1    
97   C C2    . DA  A 5  ? 1.0913 0.9033 0.8301 0.0264  0.1738  -0.0333 5   DA  B C2    
98   N N3    . DA  A 5  ? 1.0323 0.8556 0.7901 0.0492  0.1781  -0.0194 5   DA  B N3    
99   C C4    . DA  A 5  ? 0.8293 0.6945 0.6184 0.0525  0.1599  -0.0153 5   DA  B C4    
100  P P     . DC  A 6  ? 1.1835 1.1117 1.0140 0.1549  0.2093  0.0733  6   DC  B P     
101  O OP1   . DC  A 6  ? 1.0856 1.0133 0.9118 0.1885  0.2362  0.0995  6   DC  B OP1   
102  O OP2   . DC  A 6  ? 0.9973 0.9828 0.8579 0.1413  0.1819  0.0737  6   DC  B OP2   
103  O "O5'" . DC  A 6  ? 1.2430 1.1134 1.0417 0.1412  0.2153  0.0545  6   DC  B "O5'" 
104  C "C5'" . DC  A 6  ? 1.2723 1.0775 1.0309 0.1370  0.2376  0.0435  6   DC  B "C5'" 
105  C "C4'" . DC  A 6  ? 1.2930 1.0679 1.0304 0.1104  0.2309  0.0220  6   DC  B "C4'" 
106  O "O4'" . DC  A 6  ? 1.2268 1.0205 0.9744 0.0859  0.2086  0.0053  6   DC  B "O4'" 
107  C "C3'" . DC  A 6  ? 1.3270 1.1218 1.0777 0.1089  0.2189  0.0236  6   DC  B "C3'" 
108  O "O3'" . DC  A 6  ? 1.4131 1.1616 1.1325 0.1162  0.2417  0.0264  6   DC  B "O3'" 
109  C "C2'" . DC  A 6  ? 1.2921 1.0955 1.0459 0.0795  0.1970  0.0031  6   DC  B "C2'" 
110  C "C1'" . DC  A 6  ? 1.2605 1.0576 1.0070 0.0663  0.1946  -0.0072 6   DC  B "C1'" 
111  N N1    . DC  A 6  ? 1.0264 0.8659 0.8001 0.0544  0.1687  -0.0135 6   DC  B N1    
112  C C2    . DC  A 6  ? 1.0754 0.9132 0.8393 0.0320  0.1597  -0.0280 6   DC  B C2    
113  O O2    . DC  A 6  ? 0.9780 0.7822 0.7102 0.0175  0.1717  -0.0368 6   DC  B O2    
114  N N3    . DC  A 6  ? 0.9206 0.7935 0.7065 0.0264  0.1403  -0.0305 6   DC  B N3    
115  C C4    . DC  A 6  ? 0.9421 0.8429 0.7535 0.0376  0.1308  -0.0224 6   DC  B C4    
116  N N4    . DC  A 6  ? 0.9946 0.9181 0.8190 0.0320  0.1167  -0.0253 6   DC  B N4    
117  C C5    . DC  A 6  ? 0.9076 0.8151 0.7287 0.0540  0.1371  -0.0095 6   DC  B C5    
118  C C6    . DC  A 6  ? 0.9270 0.8072 0.7314 0.0643  0.1557  -0.0039 6   DC  B C6    
119  P P     . DG  A 7  ? 1.3470 1.1133 1.0782 0.1247  0.2367  0.0353  7   DG  B P     
120  O OP1   . DG  A 7  ? 1.4053 1.1354 1.1121 0.1540  0.2695  0.0545  7   DG  B OP1   
121  O OP2   . DG  A 7  ? 1.3805 1.2147 1.1553 0.1244  0.2084  0.0415  7   DG  B OP2   
122  O "O5'" . DG  A 7  ? 1.3038 1.0415 1.0132 0.0937  0.2305  0.0121  7   DG  B "O5'" 
123  C "C5'" . DG  A 7  ? 1.3849 1.0597 1.0466 0.0775  0.2523  -0.0013 7   DG  B "C5'" 
124  C "C4'" . DG  A 7  ? 1.3118 0.9858 0.9640 0.0440  0.2386  -0.0212 7   DG  B "C4'" 
125  O "O4'" . DG  A 7  ? 1.1906 0.9087 0.8689 0.0280  0.2129  -0.0301 7   DG  B "O4'" 
126  C "C3'" . DG  A 7  ? 1.2252 0.9188 0.8925 0.0445  0.2278  -0.0192 7   DG  B "C3'" 
127  O "O3'" . DG  A 7  ? 1.2176 0.8771 0.8506 0.0180  0.2356  -0.0341 7   DG  B "O3'" 
128  C "C2'" . DG  A 7  ? 1.1604 0.9171 0.8720 0.0387  0.1954  -0.0215 7   DG  B "C2'" 
129  C "C1'" . DG  A 7  ? 1.1875 0.9480 0.8946 0.0212  0.1895  -0.0325 7   DG  B "C1'" 
130  N N9    . DG  A 7  ? 1.0847 0.8932 0.8284 0.0261  0.1680  -0.0294 7   DG  B N9    
131  C C8    . DG  A 7  ? 1.0452 0.8832 0.8171 0.0457  0.1606  -0.0165 7   DG  B C8    
132  N N7    . DG  A 7  ? 0.9680 0.8395 0.7624 0.0418  0.1432  -0.0182 7   DG  B N7    
133  C C5    . DG  A 7  ? 0.9937 0.8612 0.7775 0.0229  0.1387  -0.0307 7   DG  B C5    
134  C C6    . DG  A 7  ? 0.8799 0.7740 0.6770 0.0151  0.1242  -0.0350 7   DG  B C6    
135  O O6    . DG  A 7  ? 0.9369 0.8534 0.7535 0.0222  0.1145  -0.0306 7   DG  B O6    
136  N N1    . DG  A 7  ? 0.8966 0.7894 0.6785 -0.0035 0.1234  -0.0440 7   DG  B N1    
137  C C2    . DG  A 7  ? 0.9770 0.8428 0.7304 -0.0187 0.1352  -0.0508 7   DG  B C2    
138  N N2    . DG  A 7  ? 0.9903 0.8691 0.7316 -0.0412 0.1310  -0.0582 7   DG  B N2    
139  N N3    . DG  A 7  ? 1.0675 0.8972 0.8027 -0.0129 0.1514  -0.0492 7   DG  B N3    
140  C C4    . DG  A 7  ? 1.0329 0.8670 0.7867 0.0107  0.1522  -0.0378 7   DG  B C4    
141  P P     . DG  A 8  ? 1.2166 0.8825 0.8523 0.0109  0.2295  -0.0365 8   DG  B P     
142  O OP1   . DG  A 8  ? 1.3517 0.9449 0.9297 0.0003  0.2616  -0.0425 8   DG  B OP1   
143  O OP2   . DG  A 8  ? 1.2533 0.9546 0.9241 0.0351  0.2179  -0.0218 8   DG  B OP2   
144  O "O5'" . DG  A 8  ? 1.0349 0.7453 0.6893 -0.0175 0.2035  -0.0503 8   DG  B "O5'" 
145  C "C5'" . DG  A 8  ? 1.1510 0.8458 0.7753 -0.0485 0.2084  -0.0645 8   DG  B "C5'" 
146  C "C4'" . DG  A 8  ? 1.1807 0.9331 0.8313 -0.0672 0.1828  -0.0703 8   DG  B "C4'" 
147  O "O4'" . DG  A 8  ? 1.1430 0.9357 0.8299 -0.0519 0.1657  -0.0640 8   DG  B "O4'" 
148  C "C3'" . DG  A 8  ? 1.2493 1.0278 0.9208 -0.0648 0.1716  -0.0679 8   DG  B "C3'" 
149  O "O3'" . DG  A 8  ? 1.1661 0.9737 0.8340 -0.0933 0.1627  -0.0759 8   DG  B "O3'" 
150  C "C2'" . DG  A 8  ? 1.1827 1.0033 0.8995 -0.0401 0.1529  -0.0577 8   DG  B "C2'" 
151  C "C1'" . DG  A 8  ? 1.1027 0.9400 0.8260 -0.0430 0.1466  -0.0590 8   DG  B "C1'" 
152  N N9    . DG  A 8  ? 1.0866 0.9436 0.8394 -0.0197 0.1373  -0.0498 8   DG  B N9    
153  C C8    . DG  A 8  ? 1.1302 0.9781 0.8919 0.0023  0.1419  -0.0399 8   DG  B C8    
154  N N7    . DG  A 8  ? 0.9818 0.8578 0.7692 0.0137  0.1300  -0.0339 8   DG  B N7    
155  C C5    . DG  A 8  ? 0.9327 0.8310 0.7272 0.0020  0.1188  -0.0399 8   DG  B C5    
156  C C6    . DG  A 8  ? 0.9537 0.8780 0.7676 0.0071  0.1072  -0.0372 8   DG  B C6    
157  O O6    . DG  A 8  ? 1.0455 0.9775 0.8725 0.0183  0.1036  -0.0311 8   DG  B O6    
158  N N1    . DG  A 8  ? 1.0381 0.9820 0.8529 -0.0033 0.1009  -0.0410 8   DG  B N1    
159  C C2    . DG  A 8  ? 1.0138 0.9612 0.8145 -0.0207 0.1029  -0.0465 8   DG  B C2    
160  N N2    . DG  A 8  ? 0.9123 0.8922 0.7189 -0.0276 0.0954  -0.0453 8   DG  B N2    
161  N N3    . DG  A 8  ? 0.9451 0.8664 0.7245 -0.0314 0.1134  -0.0516 8   DG  B N3    
162  C C4    . DG  A 8  ? 1.0196 0.9130 0.7962 -0.0173 0.1220  -0.0480 8   DG  B C4    
163  P P     . DG  A 9  ? 1.1164 0.9467 0.7963 -0.0980 0.1554  -0.0754 9   DG  B P     
164  O OP1   . DG  A 9  ? 1.1525 0.9718 0.7951 -0.1357 0.1647  -0.0865 9   DG  B OP1   
165  O OP2   . DG  A 9  ? 0.9262 0.7386 0.6170 -0.0728 0.1587  -0.0679 9   DG  B OP2   
166  O "O5'" . DG  A 9  ? 1.0313 0.9273 0.7515 -0.0925 0.1329  -0.0695 9   DG  B "O5'" 
167  C "C5'" . DG  A 9  ? 0.9971 0.9298 0.7133 -0.1160 0.1262  -0.0724 9   DG  B "C5'" 
168  C "C4'" . DG  A 9  ? 0.9446 0.9314 0.6991 -0.0988 0.1094  -0.0621 9   DG  B "C4'" 
169  O "O4'" . DG  A 9  ? 0.9661 0.9349 0.7351 -0.0726 0.1081  -0.0579 9   DG  B "O4'" 
170  C "C3'" . DG  A 9  ? 0.8992 0.9180 0.6778 -0.0881 0.1021  -0.0548 9   DG  B "C3'" 
171  O "O3'" . DG  A 9  ? 0.8815 0.9595 0.6726 -0.0975 0.0939  -0.0478 9   DG  B "O3'" 
172  C "C2'" . DG  A 9  ? 0.9068 0.9208 0.7095 -0.0572 0.0972  -0.0475 9   DG  B "C2'" 
173  C "C1'" . DG  A 9  ? 0.9222 0.9191 0.7208 -0.0522 0.0982  -0.0490 9   DG  B "C1'" 
174  N N9    . DG  A 9  ? 0.8796 0.8485 0.6847 -0.0323 0.0999  -0.0469 9   DG  B N9    
175  C C8    . DG  A 9  ? 0.9524 0.8852 0.7454 -0.0284 0.1089  -0.0487 9   DG  B C8    
176  N N7    . DG  A 9  ? 0.9572 0.8837 0.7618 -0.0107 0.1072  -0.0431 9   DG  B N7    
177  C C5    . DG  A 9  ? 0.9524 0.9038 0.7733 -0.0054 0.0979  -0.0401 9   DG  B C5    
178  C C6    . DG  A 9  ? 0.9343 0.8891 0.7672 0.0071  0.0935  -0.0353 9   DG  B C6    
179  O O6    . DG  A 9  ? 0.9318 0.8773 0.7666 0.0147  0.0948  -0.0314 9   DG  B O6    
180  N N1    . DG  A 9  ? 0.8867 0.8601 0.7273 0.0093  0.0883  -0.0335 9   DG  B N1    
181  C C2    . DG  A 9  ? 0.8895 0.8850 0.7311 0.0038  0.0867  -0.0330 9   DG  B C2    
182  N N2    . DG  A 9  ? 0.8075 0.8188 0.6561 0.0127  0.0846  -0.0272 9   DG  B N2    
183  N N3    . DG  A 9  ? 0.7915 0.7952 0.6253 -0.0100 0.0883  -0.0363 9   DG  B N3    
184  C C4    . DG  A 9  ? 0.9269 0.9034 0.7489 -0.0154 0.0942  -0.0413 9   DG  B C4    
185  P P     . DC  A 10 ? 0.8980 1.0127 0.7097 -0.0884 0.0902  -0.0384 10  DC  B P     
186  O OP1   . DC  A 10 ? 0.9397 1.1158 0.7514 -0.1112 0.0859  -0.0329 10  DC  B OP1   
187  O OP2   . DC  A 10 ? 0.8199 0.8979 0.6245 -0.0861 0.0963  -0.0439 10  DC  B OP2   
188  O "O5'" . DC  A 10 ? 0.9770 1.1003 0.8141 -0.0545 0.0861  -0.0271 10  DC  B "O5'" 
189  C "C5'" . DC  A 10 ? 0.9423 1.0901 0.7872 -0.0473 0.0819  -0.0201 10  DC  B "C5'" 
190  C "C4'" . DC  A 10 ? 0.9090 1.0538 0.7700 -0.0167 0.0829  -0.0101 10  DC  B "C4'" 
191  O "O4'" . DC  A 10 ? 0.8923 0.9862 0.7481 -0.0074 0.0846  -0.0178 10  DC  B "O4'" 
192  C "C3'" . DC  A 10 ? 1.0140 1.1693 0.8842 -0.0034 0.0869  -0.0020 10  DC  B "C3'" 
193  O "O3'" . DC  A 10 ? 0.8889 1.0722 0.7705 0.0190  0.0906  0.0141  10  DC  B "O3'" 
194  C "C2'" . DC  A 10 ? 0.9900 1.0915 0.8542 0.0057  0.0901  -0.0099 10  DC  B "C2'" 
195  C "C1'" . DC  A 10 ? 0.9228 0.9994 0.7829 0.0089  0.0881  -0.0145 10  DC  B "C1'" 
196  N N1    . DC  A 10 ? 0.8992 0.9335 0.7515 0.0076  0.0884  -0.0235 10  DC  B N1    
197  C C2    . DC  A 10 ? 0.8200 0.8329 0.6716 0.0186  0.0889  -0.0228 10  DC  B C2    
198  O O2    . DC  A 10 ? 0.8366 0.8556 0.6900 0.0296  0.0913  -0.0165 10  DC  B O2    
199  N N3    . DC  A 10 ? 0.8488 0.8367 0.6958 0.0167  0.0882  -0.0275 10  DC  B N3    
200  C C4    . DC  A 10 ? 0.8288 0.8070 0.6711 0.0089  0.0892  -0.0317 10  DC  B C4    
201  N N4    . DC  A 10 ? 0.8808 0.8414 0.7202 0.0113  0.0897  -0.0319 10  DC  B N4    
202  C C5    . DC  A 10 ? 0.8413 0.8292 0.6793 -0.0021 0.0911  -0.0344 10  DC  B C5    
203  C C6    . DC  A 10 ? 0.9076 0.9263 0.7513 -0.0046 0.0895  -0.0307 10  DC  B C6    
204  P P     . DA  A 11 ? 0.9799 1.2018 0.8727 0.0329  0.0972  0.0303  11  DA  B P     
205  O OP1   . DA  A 11 ? 0.9564 1.2374 0.8606 0.0428  0.0973  0.0491  11  DA  B OP1   
206  O OP2   . DA  A 11 ? 1.0442 1.2739 0.9354 0.0134  0.0951  0.0236  11  DA  B OP2   
207  O "O5'" . DA  A 11 ? 1.0523 1.2221 0.9378 0.0575  0.1081  0.0312  11  DA  B "O5'" 
208  C "C5'" . DA  A 11 ? 1.0845 1.2358 0.9647 0.0770  0.1146  0.0377  11  DA  B "C5'" 
209  C "C4'" . DA  A 11 ? 1.0702 1.1578 0.9331 0.0832  0.1219  0.0288  11  DA  B "C4'" 
210  O "O4'" . DA  A 11 ? 0.9767 1.0372 0.8357 0.0625  0.1115  0.0112  11  DA  B "O4'" 
211  C "C3'" . DA  A 11 ? 0.9898 1.0600 0.8447 0.0950  0.1345  0.0339  11  DA  B "C3'" 
212  O "O3'" . DA  A 11 ? 1.0301 1.0650 0.8662 0.1160  0.1519  0.0418  11  DA  B "O3'" 
213  C "C2'" . DA  A 11 ? 0.9319 0.9661 0.7786 0.0768  0.1279  0.0169  11  DA  B "C2'" 
214  C "C1'" . DA  A 11 ? 0.9259 0.9468 0.7719 0.0635  0.1170  0.0057  11  DA  B "C1'" 
215  N N9    . DA  A 11 ? 0.8912 0.9011 0.7378 0.0454  0.1072  -0.0066 11  DA  B N9    
216  C C8    . DA  A 11 ? 0.7900 0.8164 0.6429 0.0325  0.1017  -0.0108 11  DA  B C8    
217  N N7    . DA  A 11 ? 0.8298 0.8338 0.6774 0.0222  0.0973  -0.0199 11  DA  B N7    
218  C C5    . DA  A 11 ? 0.7780 0.7585 0.6193 0.0270  0.0974  -0.0211 11  DA  B C5    
219  C C6    . DA  A 11 ? 0.8205 0.7819 0.6569 0.0219  0.0937  -0.0256 11  DA  B C6    
220  N N6    . DA  A 11 ? 0.8670 0.8247 0.7037 0.0156  0.0912  -0.0287 11  DA  B N6    
221  N N1    . DA  A 11 ? 0.9606 0.9084 0.7898 0.0236  0.0944  -0.0251 11  DA  B N1    
222  C C2    . DA  A 11 ? 0.8488 0.7914 0.6716 0.0314  0.1012  -0.0215 11  DA  B C2    
223  N N3    . DA  A 11 ? 0.8758 0.8314 0.7019 0.0420  0.1074  -0.0152 11  DA  B N3    
224  C C4    . DA  A 11 ? 0.9162 0.8961 0.7543 0.0388  0.1037  -0.0147 11  DA  B C4    
225  P P     . DA  A 12 ? 1.1006 1.1088 0.9200 0.1331  0.1722  0.0502  12  DA  B P     
226  O OP1   . DA  A 12 ? 1.0897 1.0984 0.8995 0.1647  0.1941  0.0714  12  DA  B OP1   
227  O OP2   . DA  A 12 ? 0.9101 0.9526 0.7468 0.1235  0.1642  0.0493  12  DA  B OP2   
228  O "O5'" . DA  A 12 ? 1.0330 0.9755 0.8255 0.1164  0.1725  0.0317  12  DA  B "O5'" 
229  C "C5'" . DA  A 12 ? 1.0950 1.0087 0.8744 0.1081  0.1696  0.0233  12  DA  B "C5'" 
230  C "C4'" . DA  A 12 ? 1.1659 1.0361 0.9240 0.0870  0.1668  0.0079  12  DA  B "C4'" 
231  O "O4'" . DA  A 12 ? 1.1378 1.0325 0.9169 0.0681  0.1456  -0.0021 12  DA  B "O4'" 
232  C "C3'" . DA  A 12 ? 1.2066 1.0449 0.9424 0.0885  0.1810  0.0080  12  DA  B "C3'" 
233  O "O3'" . DA  A 12 ? 1.3318 1.1164 1.0306 0.0738  0.1893  -0.0012 12  DA  B "O3'" 
234  C "C2'" . DA  A 12 ? 1.1103 0.9749 0.8667 0.0744  0.1641  0.0011  12  DA  B "C2'" 
235  C "C1'" . DA  A 12 ? 1.0771 0.9562 0.8473 0.0579  0.1450  -0.0079 12  DA  B "C1'" 
236  N N9    . DA  A 12 ? 0.9362 0.8464 0.7298 0.0486  0.1295  -0.0120 12  DA  B N9    
237  C C8    . DA  A 12 ? 0.8955 0.8397 0.7084 0.0522  0.1262  -0.0078 12  DA  B C8    
238  N N7    . DA  A 12 ? 0.9208 0.8750 0.7431 0.0391  0.1151  -0.0146 12  DA  B N7    
239  C C5    . DA  A 12 ? 0.8179 0.7496 0.6307 0.0304  0.1103  -0.0209 12  DA  B C5    
240  C C6    . DA  A 12 ? 0.9093 0.8407 0.7252 0.0202  0.1015  -0.0256 12  DA  B C6    
241  N N6    . DA  A 12 ? 0.8984 0.8410 0.7226 0.0164  0.0982  -0.0272 12  DA  B N6    
242  N N1    . DA  A 12 ? 0.9960 0.9158 0.8033 0.0140  0.0981  -0.0271 12  DA  B N1    
243  C C2    . DA  A 12 ? 1.1117 1.0149 0.9041 0.0133  0.1036  -0.0271 12  DA  B C2    
244  N N3    . DA  A 12 ? 0.9229 0.8131 0.7054 0.0224  0.1148  -0.0244 12  DA  B N3    
245  C C4    . DA  A 12 ? 0.8567 0.7650 0.6526 0.0333  0.1175  -0.0200 12  DA  B C4    
246  P P     . DT  A 13 ? 1.3723 1.1063 1.0323 0.0696  0.2082  -0.0038 13  DT  B P     
247  O OP1   . DT  A 13 ? 1.4062 1.0867 1.0249 0.0749  0.2319  -0.0017 13  DT  B OP1   
248  O OP2   . DT  A 13 ? 1.2526 1.0022 0.9240 0.0854  0.2149  0.0046  13  DT  B OP2   
249  O "O5'" . DT  A 13 ? 1.2511 0.9896 0.9120 0.0378  0.1878  -0.0182 13  DT  B "O5'" 
250  C "C5'" . DT  A 13 ? 1.1831 0.9248 0.8425 0.0188  0.1755  -0.0256 13  DT  B "C5'" 
251  C "C4'" . DT  A 13 ? 1.1779 0.9423 0.8486 -0.0023 0.1563  -0.0322 13  DT  B "C4'" 
252  O "O4'" . DT  A 13 ? 0.9969 0.8050 0.7077 0.0086  0.1422  -0.0287 13  DT  B "O4'" 
253  C "C3'" . DT  A 13 ? 1.1538 0.8882 0.7934 -0.0168 0.1642  -0.0366 13  DT  B "C3'" 
254  O "O3'" . DT  A 13 ? 1.1927 0.9236 0.8124 -0.0460 0.1565  -0.0432 13  DT  B "O3'" 
255  C "C2'" . DT  A 13 ? 1.1355 0.9041 0.8056 -0.0109 0.1516  -0.0344 13  DT  B "C2'" 
256  C "C1'" . DT  A 13 ? 1.0080 0.8216 0.7183 -0.0038 0.1344  -0.0319 13  DT  B "C1'" 
257  N N1    . DT  A 13 ? 0.9595 0.8030 0.6997 0.0079  0.1276  -0.0285 13  DT  B N1    
258  C C2    . DT  A 13 ? 0.9117 0.7790 0.6692 0.0010  0.1134  -0.0296 13  DT  B C2    
259  O O2    . DT  A 13 ? 0.9068 0.7788 0.6601 -0.0110 0.1057  -0.0306 13  DT  B O2    
260  N N3    . DT  A 13 ? 0.8997 0.7852 0.6762 0.0085  0.1108  -0.0281 13  DT  B N3    
261  C C4    . DT  A 13 ? 0.8739 0.7669 0.6579 0.0197  0.1181  -0.0249 13  DT  B C4    
262  O O4    . DT  A 13 ? 0.9173 0.8287 0.7153 0.0200  0.1148  -0.0246 13  DT  B O4    
263  C C5    . DT  A 13 ? 0.9318 0.8088 0.7025 0.0302  0.1318  -0.0206 13  DT  B C5    
264  C C7    . DT  A 13 ? 0.9406 0.8355 0.7213 0.0463  0.1414  -0.0118 13  DT  B C7    
265  C C6    . DT  A 13 ? 0.9797 0.8274 0.7271 0.0249  0.1373  -0.0230 13  DT  B C6    
266  P P     . DT  A 14 ? 1.2287 0.9277 0.8041 -0.0743 0.1632  -0.0498 14  DT  B P     
267  O OP1   . DT  A 14 ? 1.3266 1.0084 0.8692 -0.1019 0.1658  -0.0555 14  DT  B OP1   
268  O OP2   . DT  A 14 ? 1.2457 0.9009 0.7984 -0.0583 0.1858  -0.0485 14  DT  B OP2   
269  O "O5'" . DT  A 14 ? 1.1102 0.8595 0.7153 -0.0821 0.1404  -0.0474 14  DT  B "O5'" 
270  C "C5'" . DT  A 14 ? 1.1331 0.9308 0.7685 -0.0859 0.1212  -0.0435 14  DT  B "C5'" 
271  C "C4'" . DT  A 14 ? 1.0923 0.9285 0.7496 -0.0869 0.1063  -0.0381 14  DT  B "C4'" 
272  O "O4'" . DT  A 14 ? 0.9652 0.8112 0.6539 -0.0607 0.1052  -0.0350 14  DT  B "O4'" 
273  C "C3'" . DT  A 14 ? 1.1128 0.9327 0.7383 -0.1071 0.1097  -0.0408 14  DT  B "C3'" 
274  O "O3'" . DT  A 14 ? 1.1976 1.0628 0.8289 -0.1254 0.0939  -0.0343 14  DT  B "O3'" 
275  C "C2'" . DT  A 14 ? 1.0379 0.8553 0.6808 -0.0865 0.1117  -0.0389 14  DT  B "C2'" 
276  C "C1'" . DT  A 14 ? 0.9994 0.8492 0.6866 -0.0627 0.1028  -0.0334 14  DT  B "C1'" 
277  N N1    . DT  A 14 ? 0.8644 0.7073 0.5687 -0.0411 0.1088  -0.0334 14  DT  B N1    
278  C C2    . DT  A 14 ? 0.8553 0.7231 0.5862 -0.0305 0.1010  -0.0294 14  DT  B C2    
279  O O2    . DT  A 14 ? 0.9333 0.8251 0.6738 -0.0334 0.0913  -0.0241 14  DT  B O2    
280  N N3    . DT  A 14 ? 0.8688 0.7327 0.6114 -0.0165 0.1072  -0.0302 14  DT  B N3    
281  C C4    . DT  A 14 ? 0.8800 0.7263 0.6157 -0.0080 0.1196  -0.0312 14  DT  B C4    
282  O O4    . DT  A 14 ? 0.8823 0.7390 0.6327 0.0028  0.1228  -0.0293 14  DT  B O4    
283  C C5    . DT  A 14 ? 0.9910 0.8080 0.6991 -0.0135 0.1298  -0.0333 14  DT  B C5    
284  C C7    . DT  A 14 ? 1.0300 0.8224 0.7251 0.0008  0.1486  -0.0307 14  DT  B C7    
285  C C6    . DT  A 14 ? 0.9705 0.7837 0.6622 -0.0317 0.1241  -0.0359 14  DT  B C6    
286  P P     . DA  A 15 ? 1.1689 1.0405 0.7699 -0.1544 0.0905  -0.0336 15  DA  B P     
287  O OP1   . DA  A 15 ? 1.0947 1.0244 0.7011 -0.1754 0.0745  -0.0236 15  DA  B OP1   
288  O OP2   . DA  A 15 ? 1.3088 1.1170 0.8586 -0.1718 0.1095  -0.0457 15  DA  B OP2   
289  O "O5'" . DA  A 15 ? 1.1323 1.0210 0.7628 -0.1304 0.0852  -0.0267 15  DA  B "O5'" 
290  C "C5'" . DA  A 15 ? 1.0592 1.0038 0.7230 -0.1201 0.0704  -0.0126 15  DA  B "C5'" 
291  C "C4'" . DA  A 15 ? 1.0380 0.9783 0.7177 -0.0991 0.0719  -0.0097 15  DA  B "C4'" 
292  O "O4'" . DA  A 15 ? 0.9872 0.8897 0.6738 -0.0807 0.0829  -0.0189 15  DA  B "O4'" 
293  C "C3'" . DA  A 15 ? 1.0486 0.9772 0.7000 -0.1162 0.0736  -0.0112 15  DA  B "C3'" 
294  O "O3'" . DA  A 15 ? 1.0608 1.0144 0.7279 -0.1039 0.0680  -0.0003 15  DA  B "O3'" 
295  C "C2'" . DA  A 15 ? 1.0605 0.9332 0.6973 -0.1089 0.0893  -0.0241 15  DA  B "C2'" 
296  C "C1'" . DA  A 15 ? 1.0356 0.9153 0.7100 -0.0795 0.0894  -0.0222 15  DA  B "C1'" 
297  N N9    . DA  A 15 ? 0.9708 0.8161 0.6448 -0.0661 0.1024  -0.0298 15  DA  B N9    
298  C C8    . DA  A 15 ? 0.9954 0.8034 0.6443 -0.0704 0.1161  -0.0368 15  DA  B C8    
299  N N7    . DA  A 15 ? 0.9963 0.7899 0.6556 -0.0507 0.1265  -0.0376 15  DA  B N7    
300  C C5    . DA  A 15 ? 0.9097 0.7315 0.6005 -0.0380 0.1179  -0.0336 15  DA  B C5    
301  C C6    . DA  A 15 ? 0.9303 0.7590 0.6423 -0.0211 0.1218  -0.0324 15  DA  B C6    
302  N N6    . DA  A 15 ? 0.9311 0.7484 0.6425 -0.0094 0.1342  -0.0321 15  DA  B N6    
303  N N1    . DA  A 15 ? 0.8894 0.7387 0.6208 -0.0173 0.1141  -0.0300 15  DA  B N1    
304  C C2    . DA  A 15 ? 0.8610 0.7237 0.5930 -0.0235 0.1046  -0.0263 15  DA  B C2    
305  N N3    . DA  A 15 ? 0.9141 0.7826 0.6328 -0.0363 0.0986  -0.0239 15  DA  B N3    
306  C C4    . DA  A 15 ? 0.8933 0.7408 0.5909 -0.0459 0.1049  -0.0291 15  DA  B C4    
307  P P     . DG  A 16 ? 1.1010 1.1143 0.7705 -0.1146 0.0548  0.0178  16  DG  B P     
308  O OP1   . DG  A 16 ? 1.1379 1.1939 0.8307 -0.1079 0.0476  0.0290  16  DG  B OP1   
309  O OP2   . DG  A 16 ? 1.1543 1.1718 0.7868 -0.1486 0.0517  0.0164  16  DG  B OP2   
310  O "O5'" . DG  A 16 ? 1.0595 1.0668 0.7475 -0.0865 0.0586  0.0240  16  DG  B "O5'" 
311  C "C5'" . DG  A 16 ? 1.0123 1.0119 0.7285 -0.0575 0.0636  0.0253  16  DG  B "C5'" 
312  C "C4'" . DG  A 16 ? 0.9782 0.9679 0.7008 -0.0381 0.0695  0.0310  16  DG  B "C4'" 
313  O "O4'" . DG  A 16 ? 1.1071 1.0525 0.8276 -0.0338 0.0788  0.0153  16  DG  B "O4'" 
314  C "C3'" . DG  A 16 ? 0.9558 0.9596 0.6632 -0.0454 0.0666  0.0402  16  DG  B "C3'" 
315  O "O3'" . DG  A 16 ? 0.9390 0.9422 0.6563 -0.0211 0.0731  0.0516  16  DG  B "O3'" 
316  C "C2'" . DG  A 16 ? 0.9955 0.9558 0.6812 -0.0601 0.0722  0.0225  16  DG  B "C2'" 
317  C "C1'" . DG  A 16 ? 1.0541 0.9810 0.7541 -0.0450 0.0814  0.0103  16  DG  B "C1'" 
318  N N9    . DG  A 16 ? 0.9953 0.8907 0.6826 -0.0555 0.0872  -0.0047 16  DG  B N9    
319  C C8    . DG  A 16 ? 1.0586 0.9468 0.7251 -0.0752 0.0868  -0.0105 16  DG  B C8    
320  N N7    . DG  A 16 ? 0.9832 0.8353 0.6397 -0.0745 0.0980  -0.0216 16  DG  B N7    
321  C C5    . DG  A 16 ? 0.9592 0.8050 0.6361 -0.0547 0.1031  -0.0225 16  DG  B C5    
322  C C6    . DG  A 16 ? 0.9405 0.7635 0.6204 -0.0444 0.1148  -0.0289 16  DG  B C6    
323  O O6    . DG  A 16 ? 1.1145 0.9143 0.7802 -0.0453 0.1250  -0.0336 16  DG  B O6    
324  N N1    . DG  A 16 ? 0.9278 0.7585 0.6276 -0.0315 0.1158  -0.0274 16  DG  B N1    
325  C C2    . DG  A 16 ? 0.8824 0.7285 0.5927 -0.0275 0.1099  -0.0218 16  DG  B C2    
326  N N2    . DG  A 16 ? 0.8327 0.6769 0.5548 -0.0191 0.1148  -0.0232 16  DG  B N2    
327  N N3    . DG  A 16 ? 0.8367 0.7008 0.5446 -0.0312 0.1013  -0.0137 16  DG  B N3    
328  C C4    . DG  A 16 ? 0.8617 0.7296 0.5547 -0.0455 0.0970  -0.0140 16  DG  B C4    
329  O "O5'" . DC  B 1  ? 1.5247 1.4668 1.4079 0.1154  0.1909  0.0328  1   DC  D "O5'" 
330  C "C5'" . DC  B 1  ? 1.1812 1.1837 1.1110 0.1024  0.1759  0.0343  1   DC  D "C5'" 
331  C "C4'" . DC  B 1  ? 1.0008 0.9933 0.9401 0.0731  0.1591  0.0155  1   DC  D "C4'" 
332  O "O4'" . DC  B 1  ? 0.9730 0.9091 0.8762 0.0652  0.1616  0.0039  1   DC  D "O4'" 
333  C "C3'" . DC  B 1  ? 0.8537 0.8685 0.8149 0.0559  0.1438  0.0075  1   DC  D "C3'" 
334  O "O3'" . DC  B 1  ? 0.8244 0.8549 0.8075 0.0360  0.1324  -0.0004 1   DC  D "O3'" 
335  C "C2'" . DC  B 1  ? 0.9414 0.9103 0.8741 0.0504  0.1435  -0.0030 1   DC  D "C2'" 
336  C "C1'" . DC  B 1  ? 0.9037 0.8348 0.8107 0.0464  0.1486  -0.0077 1   DC  D "C1'" 
337  N N1    . DC  B 1  ? 0.8580 0.7367 0.7208 0.0430  0.1552  -0.0135 1   DC  D N1    
338  C C2    . DC  B 1  ? 0.8064 0.6668 0.6563 0.0196  0.1460  -0.0240 1   DC  D C2    
339  O O2    . DC  B 1  ? 0.8385 0.7249 0.7145 0.0074  0.1345  -0.0268 1   DC  D O2    
340  N N3    . DC  B 1  ? 0.8438 0.6578 0.6485 0.0103  0.1517  -0.0289 1   DC  D N3    
341  C C4    . DC  B 1  ? 0.9453 0.7205 0.7139 0.0260  0.1687  -0.0250 1   DC  D C4    
342  N N4    . DC  B 1  ? 0.9804 0.7000 0.6954 0.0123  0.1762  -0.0312 1   DC  D N4    
343  C C5    . DC  B 1  ? 0.9644 0.7568 0.7471 0.0561  0.1804  -0.0123 1   DC  D C5    
344  C C6    . DC  B 1  ? 0.9108 0.7607 0.7431 0.0620  0.1715  -0.0064 1   DC  D C6    
345  P P     . DT  B 2  ? 0.7812 0.8436 0.7884 0.0193  0.1209  -0.0045 2   DT  D P     
346  O OP1   . DT  B 2  ? 0.7250 0.8023 0.7482 0.0036  0.1167  -0.0073 2   DT  D OP1   
347  O OP2   . DT  B 2  ? 0.8369 0.9312 0.8502 0.0281  0.1220  0.0060  2   DT  D OP2   
348  O "O5'" . DT  B 2  ? 0.8703 0.8996 0.8646 0.0118  0.1160  -0.0166 2   DT  D "O5'" 
349  C "C5'" . DT  B 2  ? 0.8439 0.8511 0.8335 0.0029  0.1137  -0.0237 2   DT  D "C5'" 
350  C "C4'" . DT  B 2  ? 0.7963 0.7831 0.7737 -0.0026 0.1099  -0.0300 2   DT  D "C4'" 
351  O "O4'" . DT  B 2  ? 0.8345 0.7951 0.7839 0.0043  0.1156  -0.0287 2   DT  D "O4'" 
352  C "C3'" . DT  B 2  ? 0.7257 0.7236 0.7125 -0.0074 0.1049  -0.0335 2   DT  D "C3'" 
353  O "O3'" . DT  B 2  ? 0.7476 0.7379 0.7358 -0.0161 0.1011  -0.0380 2   DT  D "O3'" 
354  C "C2'" . DT  B 2  ? 0.7834 0.7698 0.7527 0.0013  0.1080  -0.0313 2   DT  D "C2'" 
355  C "C1'" . DT  B 2  ? 0.8201 0.7749 0.7633 0.0017  0.1128  -0.0318 2   DT  D "C1'" 
356  N N1    . DT  B 2  ? 0.8065 0.7319 0.7181 0.0122  0.1228  -0.0286 2   DT  D N1    
357  C C2    . DT  B 2  ? 0.7704 0.6600 0.6495 0.0016  0.1246  -0.0332 2   DT  D C2    
358  O O2    . DT  B 2  ? 0.8317 0.7255 0.7139 -0.0148 0.1165  -0.0371 2   DT  D O2    
359  N N3    . DT  B 2  ? 0.8040 0.6539 0.6441 0.0099  0.1374  -0.0313 2   DT  D N3    
360  C C4    . DT  B 2  ? 0.8805 0.7267 0.7144 0.0333  0.1499  -0.0225 2   DT  D C4    
361  O O4    . DT  B 2  ? 0.9213 0.7198 0.7110 0.0417  0.1655  -0.0203 2   DT  D O4    
362  C C5    . DT  B 2  ? 0.8807 0.7798 0.7573 0.0448  0.1451  -0.0148 2   DT  D C5    
363  C C7    . DT  B 2  ? 0.8863 0.8004 0.7633 0.0709  0.1573  0.0002  2   DT  D C7    
364  C C6    . DT  B 2  ? 0.8102 0.7436 0.7210 0.0308  0.1314  -0.0198 2   DT  D C6    
365  P P     . DA  B 3  ? 0.7431 0.7412 0.7451 -0.0232 0.1001  -0.0414 3   DA  D P     
366  O OP1   . DA  B 3  ? 0.6672 0.6641 0.6759 -0.0259 0.1041  -0.0402 3   DA  D OP1   
367  O OP2   . DA  B 3  ? 0.7293 0.7374 0.7336 -0.0266 0.0982  -0.0443 3   DA  D OP2   
368  O "O5'" . DA  B 3  ? 0.6638 0.6533 0.6587 -0.0239 0.0984  -0.0400 3   DA  D "O5'" 
369  C "C5'" . DA  B 3  ? 0.6563 0.6468 0.6523 -0.0246 0.0994  -0.0349 3   DA  D "C5'" 
370  C "C4'" . DA  B 3  ? 0.6421 0.6369 0.6312 -0.0293 0.0955  -0.0311 3   DA  D "C4'" 
371  O "O4'" . DA  B 3  ? 0.6363 0.6179 0.6044 -0.0346 0.0928  -0.0340 3   DA  D "O4'" 
372  C "C3'" . DA  B 3  ? 0.5966 0.5970 0.5922 -0.0284 0.0959  -0.0312 3   DA  D "C3'" 
373  O "O3'" . DA  B 3  ? 0.6689 0.6860 0.6649 -0.0319 0.0937  -0.0219 3   DA  D "O3'" 
374  C "C2'" . DA  B 3  ? 0.6470 0.6377 0.6319 -0.0307 0.0927  -0.0380 3   DA  D "C2'" 
375  C "C1'" . DA  B 3  ? 0.6616 0.6407 0.6263 -0.0359 0.0910  -0.0372 3   DA  D "C1'" 
376  N N9    . DA  B 3  ? 0.6821 0.6431 0.6312 -0.0313 0.0938  -0.0411 3   DA  D N9    
377  C C8    . DA  B 3  ? 0.7000 0.6644 0.6564 -0.0211 0.0968  -0.0420 3   DA  D C8    
378  N N7    . DA  B 3  ? 0.7123 0.6605 0.6495 -0.0142 0.1017  -0.0408 3   DA  D N7    
379  C C5    . DA  B 3  ? 0.6266 0.5500 0.5369 -0.0236 0.1024  -0.0422 3   DA  D C5    
380  C C6    . DA  B 3  ? 0.7543 0.6416 0.6271 -0.0235 0.1100  -0.0425 3   DA  D C6    
381  N N6    . DA  B 3  ? 0.7850 0.6584 0.6459 -0.0063 0.1200  -0.0387 3   DA  D N6    
382  N N1    . DA  B 3  ? 0.8240 0.6904 0.6688 -0.0425 0.1084  -0.0450 3   DA  D N1    
383  C C2    . DA  B 3  ? 0.8489 0.7413 0.7098 -0.0572 0.0987  -0.0439 3   DA  D C2    
384  N N3    . DA  B 3  ? 0.8378 0.7663 0.7364 -0.0525 0.0929  -0.0411 3   DA  D N3    
385  C C4    . DA  B 3  ? 0.6360 0.5727 0.5550 -0.0365 0.0957  -0.0420 3   DA  D C4    
386  P P     . DA  B 4  ? 0.6888 0.7180 0.6920 -0.0287 0.0959  -0.0171 4   DA  D P     
387  O OP1   . DA  B 4  ? 0.5723 0.6250 0.5866 -0.0215 0.1010  -0.0015 4   DA  D OP1   
388  O OP2   . DA  B 4  ? 0.5912 0.6018 0.5953 -0.0237 0.1005  -0.0272 4   DA  D OP2   
389  O "O5'" . DA  B 4  ? 0.6641 0.6979 0.6533 -0.0422 0.0876  -0.0175 4   DA  D "O5'" 
390  C "C5'" . DA  B 4  ? 0.6849 0.7246 0.6592 -0.0565 0.0818  -0.0133 4   DA  D "C5'" 
391  C "C4'" . DA  B 4  ? 0.6449 0.6742 0.5961 -0.0724 0.0769  -0.0172 4   DA  D "C4'" 
392  O "O4'" . DA  B 4  ? 0.6760 0.6685 0.6113 -0.0679 0.0800  -0.0294 4   DA  D "O4'" 
393  C "C3'" . DA  B 4  ? 0.6745 0.7198 0.6339 -0.0725 0.0761  -0.0135 4   DA  D "C3'" 
394  O "O3'" . DA  B 4  ? 0.7781 0.8388 0.7210 -0.0944 0.0698  -0.0067 4   DA  D "O3'" 
395  C "C2'" . DA  B 4  ? 0.6358 0.6499 0.5875 -0.0656 0.0787  -0.0263 4   DA  D "C2'" 
396  C "C1'" . DA  B 4  ? 0.6890 0.6720 0.6163 -0.0696 0.0799  -0.0333 4   DA  D "C1'" 
397  N N9    . DA  B 4  ? 0.6808 0.6430 0.6074 -0.0556 0.0846  -0.0408 4   DA  D N9    
398  C C8    . DA  B 4  ? 0.6447 0.6146 0.5924 -0.0422 0.0869  -0.0430 4   DA  D C8    
399  N N7    . DA  B 4  ? 0.5732 0.5312 0.5145 -0.0338 0.0901  -0.0460 4   DA  D N7    
400  C C5    . DA  B 4  ? 0.6197 0.5520 0.5311 -0.0381 0.0929  -0.0462 4   DA  D C5    
401  C C6    . DA  B 4  ? 0.6746 0.5823 0.5638 -0.0286 0.1005  -0.0459 4   DA  D C6    
402  N N6    . DA  B 4  ? 0.6727 0.5915 0.5735 -0.0124 0.1041  -0.0428 4   DA  D N6    
403  N N1    . DA  B 4  ? 0.7074 0.5790 0.5581 -0.0372 0.1058  -0.0468 4   DA  D N1    
404  C C2    . DA  B 4  ? 0.7445 0.6148 0.5837 -0.0589 0.1002  -0.0480 4   DA  D C2    
405  N N3    . DA  B 4  ? 0.7544 0.6592 0.6184 -0.0689 0.0910  -0.0456 4   DA  D N3    
406  C C4    . DA  B 4  ? 0.6803 0.6113 0.5794 -0.0548 0.0892  -0.0447 4   DA  D C4    
407  P P     . DT  B 5  ? 0.7644 0.8502 0.7144 -0.0989 0.0681  0.0007  5   DT  D P     
408  O OP1   . DT  B 5  ? 0.7298 0.8617 0.6784 -0.1194 0.0613  0.0179  5   DT  D OP1   
409  O OP2   . DT  B 5  ? 0.6796 0.7687 0.6553 -0.0740 0.0756  0.0006  5   DT  D OP2   
410  O "O5'" . DT  B 5  ? 0.7818 0.8236 0.6971 -0.1126 0.0672  -0.0129 5   DT  D "O5'" 
411  C "C5'" . DT  B 5  ? 0.8452 0.8663 0.7220 -0.1386 0.0642  -0.0153 5   DT  D "C5'" 
412  C "C4'" . DT  B 5  ? 0.8920 0.8679 0.7343 -0.1469 0.0681  -0.0255 5   DT  D "C4'" 
413  O "O4'" . DT  B 5  ? 0.8388 0.7791 0.6822 -0.1221 0.0761  -0.0356 5   DT  D "O4'" 
414  C "C3'" . DT  B 5  ? 0.8502 0.8476 0.7040 -0.1491 0.0658  -0.0210 5   DT  D "C3'" 
415  O "O3'" . DT  B 5  ? 1.0059 0.9783 0.8164 -0.1782 0.0653  -0.0232 5   DT  D "O3'" 
416  C "C2'" . DT  B 5  ? 0.8843 0.8612 0.7532 -0.1212 0.0720  -0.0296 5   DT  D "C2'" 
417  C "C1'" . DT  B 5  ? 0.8438 0.7739 0.6874 -0.1143 0.0788  -0.0389 5   DT  D "C1'" 
418  N N1    . DT  B 5  ? 0.8359 0.7583 0.6985 -0.0869 0.0838  -0.0438 5   DT  D N1    
419  C C2    . DT  B 5  ? 0.8121 0.6952 0.6488 -0.0775 0.0924  -0.0482 5   DT  D C2    
420  O O2    . DT  B 5  ? 0.9484 0.7927 0.7438 -0.0885 0.0986  -0.0498 5   DT  D O2    
421  N N3    . DT  B 5  ? 0.8256 0.7156 0.6825 -0.0550 0.0953  -0.0488 5   DT  D N3    
422  C C4    . DT  B 5  ? 0.7908 0.7141 0.6846 -0.0457 0.0907  -0.0485 5   DT  D C4    
423  O O4    . DT  B 5  ? 0.8155 0.7447 0.7201 -0.0311 0.0932  -0.0484 5   DT  D O4    
424  C C5    . DT  B 5  ? 0.7890 0.7387 0.7024 -0.0548 0.0848  -0.0461 5   DT  D C5    
425  C C7    . DT  B 5  ? 0.7427 0.7153 0.6861 -0.0452 0.0843  -0.0460 5   DT  D C7    
426  C C6    . DT  B 5  ? 0.7434 0.6958 0.6435 -0.0723 0.0817  -0.0422 5   DT  D C6    
427  P P     . DT  B 6  ? 1.0613 1.0543 0.8725 -0.1909 0.0623  -0.0174 6   DT  D P     
428  O OP1   . DT  B 6  ? 1.0717 1.0681 0.8440 -0.2337 0.0567  -0.0123 6   DT  D OP1   
429  O OP2   . DT  B 6  ? 0.9057 0.9520 0.7677 -0.1691 0.0602  -0.0072 6   DT  D OP2   
430  O "O5'" . DT  B 6  ? 1.0612 0.9966 0.8479 -0.1792 0.0716  -0.0300 6   DT  D "O5'" 
431  C "C5'" . DT  B 6  ? 1.1540 1.0226 0.8822 -0.1942 0.0803  -0.0391 6   DT  D "C5'" 
432  C "C4'" . DT  B 6  ? 1.2414 1.0655 0.9586 -0.1691 0.0918  -0.0463 6   DT  D "C4'" 
433  O "O4'" . DT  B 6  ? 1.1234 0.9589 0.8764 -0.1349 0.0936  -0.0477 6   DT  D "O4'" 
434  C "C3'" . DT  B 6  ? 1.1155 0.9558 0.8462 -0.1663 0.0900  -0.0438 6   DT  D "C3'" 
435  O "O3'" . DT  B 6  ? 1.2796 1.0674 0.9576 -0.1830 0.0989  -0.0472 6   DT  D "O3'" 
436  C "C2'" . DT  B 6  ? 1.1836 1.0269 0.9448 -0.1292 0.0939  -0.0462 6   DT  D "C2'" 
437  C "C1'" . DT  B 6  ? 1.2295 1.0565 0.9902 -0.1134 0.0987  -0.0490 6   DT  D "C1'" 
438  N N1    . DT  B 6  ? 1.0780 0.9407 0.8855 -0.0884 0.0949  -0.0484 6   DT  D N1    
439  C C2    . DT  B 6  ? 0.9863 0.8363 0.7960 -0.0642 0.1019  -0.0490 6   DT  D C2    
440  O O2    . DT  B 6  ? 1.0143 0.8246 0.7909 -0.0561 0.1133  -0.0481 6   DT  D O2    
441  N N3    . DT  B 6  ? 0.9033 0.7890 0.7521 -0.0498 0.0968  -0.0488 6   DT  D N3    
442  C C4    . DT  B 6  ? 0.8399 0.7603 0.7200 -0.0542 0.0890  -0.0489 6   DT  D C4    
443  O O4    . DT  B 6  ? 0.8430 0.7828 0.7474 -0.0431 0.0876  -0.0499 6   DT  D O4    
444  C C5    . DT  B 6  ? 0.9287 0.8611 0.8070 -0.0728 0.0844  -0.0457 6   DT  D C5    
445  C C7    . DT  B 6  ? 1.0228 0.9933 0.9328 -0.0720 0.0801  -0.0410 6   DT  D C7    
446  C C6    . DT  B 6  ? 1.0408 0.9493 0.8852 -0.0906 0.0859  -0.0452 6   DT  D C6    
447  P P     . DG  B 7  ? 1.2384 1.0427 0.9182 -0.1952 0.0958  -0.0434 7   DG  D P     
448  O OP1   . DG  B 7  ? 1.3585 1.1166 0.9747 -0.2338 0.1012  -0.0453 7   DG  D OP1   
449  O OP2   . DG  B 7  ? 1.0631 0.9417 0.8006 -0.1887 0.0836  -0.0349 7   DG  D OP2   
450  O "O5'" . DG  B 7  ? 1.1457 0.9217 0.8287 -0.1604 0.1060  -0.0469 7   DG  D "O5'" 
451  C "C5'" . DG  B 7  ? 1.2146 0.9181 0.8450 -0.1528 0.1233  -0.0508 7   DG  D "C5'" 
452  C "C4'" . DG  B 7  ? 1.1764 0.8855 0.8307 -0.1155 0.1285  -0.0484 7   DG  D "C4'" 
453  O "O4'" . DG  B 7  ? 1.0127 0.7678 0.7178 -0.0938 0.1204  -0.0477 7   DG  D "O4'" 
454  C "C3'" . DG  B 7  ? 1.1251 0.8639 0.8004 -0.1172 0.1221  -0.0460 7   DG  D "C3'" 
455  O "O3'" . DG  B 7  ? 1.1100 0.8068 0.7560 -0.1000 0.1362  -0.0439 7   DG  D "O3'" 
456  C "C2'" . DG  B 7  ? 0.9937 0.7954 0.7311 -0.0980 0.1102  -0.0449 7   DG  D "C2'" 
457  C "C1'" . DG  B 7  ? 0.9347 0.7313 0.6800 -0.0782 0.1136  -0.0457 7   DG  D "C1'" 
458  N N9    . DG  B 7  ? 0.9458 0.7907 0.7373 -0.0724 0.1030  -0.0465 7   DG  D N9    
459  C C8    . DG  B 7  ? 0.9821 0.8639 0.7994 -0.0854 0.0933  -0.0457 7   DG  D C8    
460  N N7    . DG  B 7  ? 0.9158 0.8259 0.7667 -0.0721 0.0894  -0.0464 7   DG  D N7    
461  C C5    . DG  B 7  ? 0.9162 0.8140 0.7654 -0.0529 0.0943  -0.0478 7   DG  D C5    
462  C C6    . DG  B 7  ? 0.8676 0.7860 0.7414 -0.0381 0.0926  -0.0485 7   DG  D C6    
463  O O6    . DG  B 7  ? 0.9163 0.8586 0.8149 -0.0386 0.0880  -0.0503 7   DG  D O6    
464  N N1    . DG  B 7  ? 0.8081 0.7176 0.6726 -0.0219 0.0985  -0.0449 7   DG  D N1    
465  C C2    . DG  B 7  ? 0.8201 0.6985 0.6539 -0.0155 0.1078  -0.0406 7   DG  D C2    
466  N N2    . DG  B 7  ? 0.8123 0.6937 0.6433 0.0053  0.1147  -0.0325 7   DG  D N2    
467  N N3    . DG  B 7  ? 0.9240 0.7703 0.7283 -0.0295 0.1116  -0.0421 7   DG  D N3    
468  C C4    . DG  B 7  ? 0.9712 0.8326 0.7864 -0.0501 0.1031  -0.0461 7   DG  D C4    
469  P P     . DC  B 8  ? 1.1075 0.8149 0.7582 -0.0996 0.1352  -0.0411 8   DC  D P     
470  O OP1   . DC  B 8  ? 1.1941 0.8222 0.7762 -0.1049 0.1549  -0.0409 8   DC  D OP1   
471  O OP2   . DC  B 8  ? 1.0659 0.8207 0.7438 -0.1230 0.1208  -0.0411 8   DC  D OP2   
472  O "O5'" . DC  B 8  ? 1.0919 0.8346 0.7832 -0.0637 0.1332  -0.0372 8   DC  D "O5'" 
473  C "C5'" . DC  B 8  ? 0.9832 0.7038 0.6627 -0.0364 0.1451  -0.0321 8   DC  D "C5'" 
474  C "C4'" . DC  B 8  ? 0.9743 0.7518 0.7029 -0.0150 0.1358  -0.0289 8   DC  D "C4'" 
475  O "O4'" . DC  B 8  ? 0.9764 0.7920 0.7411 -0.0247 0.1223  -0.0351 8   DC  D "O4'" 
476  C "C3'" . DC  B 8  ? 0.9424 0.7508 0.6912 -0.0140 0.1287  -0.0281 8   DC  D "C3'" 
477  O "O3'" . DC  B 8  ? 0.8720 0.6648 0.6019 0.0091  0.1408  -0.0175 8   DC  D "O3'" 
478  C "C2'" . DC  B 8  ? 0.9300 0.7935 0.7258 -0.0126 0.1146  -0.0320 8   DC  D "C2'" 
479  C "C1'" . DC  B 8  ? 0.9196 0.7818 0.7215 -0.0136 0.1138  -0.0343 8   DC  D "C1'" 
480  N N1    . DC  B 8  ? 0.8307 0.7229 0.6627 -0.0262 0.1027  -0.0411 8   DC  D N1    
481  C C2    . DC  B 8  ? 0.7775 0.7007 0.6369 -0.0180 0.0975  -0.0421 8   DC  D C2    
482  O O2    . DC  B 8  ? 0.8724 0.8059 0.7333 -0.0031 0.0999  -0.0363 8   DC  D O2    
483  N N3    . DC  B 8  ? 0.7017 0.6435 0.5828 -0.0268 0.0912  -0.0473 8   DC  D N3    
484  C C4    . DC  B 8  ? 0.8286 0.7685 0.7097 -0.0402 0.0896  -0.0486 8   DC  D C4    
485  N N4    . DC  B 8  ? 0.8066 0.7660 0.7087 -0.0433 0.0864  -0.0502 8   DC  D N4    
486  C C5    . DC  B 8  ? 0.7895 0.7087 0.6467 -0.0516 0.0923  -0.0462 8   DC  D C5    
487  C C6    . DC  B 8  ? 0.7916 0.6822 0.6220 -0.0457 0.0991  -0.0441 8   DC  D C6    
488  P P     . DC  B 9  ? 1.0058 0.8342 0.7542 0.0195  0.1360  -0.0123 9   DC  D P     
489  O OP1   . DC  B 9  ? 0.9423 0.7432 0.6600 0.0451  0.1535  0.0025  9   DC  D OP1   
490  O OP2   . DC  B 9  ? 0.8871 0.7209 0.6406 -0.0022 0.1279  -0.0204 9   DC  D OP2   
491  O "O5'" . DC  B 9  ? 0.9695 0.8594 0.7620 0.0250  0.1224  -0.0128 9   DC  D "O5'" 
492  C "C5'" . DC  B 9  ? 0.9338 0.8476 0.7356 0.0458  0.1255  -0.0014 9   DC  D "C5'" 
493  C "C4'" . DC  B 9  ? 0.8261 0.7934 0.6643 0.0371  0.1104  -0.0064 9   DC  D "C4'" 
494  O "O4'" . DC  B 9  ? 0.7603 0.7199 0.6096 0.0174  0.1032  -0.0211 9   DC  D "O4'" 
495  C "C3'" . DC  B 9  ? 0.8319 0.8314 0.6813 0.0300  0.1016  -0.0080 9   DC  D "C3'" 
496  O "O3'" . DC  B 9  ? 0.8774 0.9197 0.7338 0.0431  0.1005  0.0066  9   DC  D "O3'" 
497  C "C2'" . DC  B 9  ? 0.8719 0.8858 0.7411 0.0094  0.0909  -0.0229 9   DC  D "C2'" 
498  C "C1'" . DC  B 9  ? 0.7513 0.7465 0.6238 0.0070  0.0926  -0.0275 9   DC  D "C1'" 
499  N N1    . DC  B 9  ? 0.7668 0.7492 0.6461 -0.0086 0.0894  -0.0394 9   DC  D N1    
500  C C2    . DC  B 9  ? 0.8185 0.8160 0.7148 -0.0171 0.0845  -0.0464 9   DC  D C2    
501  O O2    . DC  B 9  ? 0.7973 0.8186 0.7015 -0.0172 0.0809  -0.0452 9   DC  D O2    
502  N N3    . DC  B 9  ? 0.8178 0.8057 0.7199 -0.0258 0.0847  -0.0526 9   DC  D N3    
503  C C4    . DC  B 9  ? 0.7608 0.7336 0.6551 -0.0296 0.0872  -0.0513 9   DC  D C4    
504  N N4    . DC  B 9  ? 0.7142 0.6896 0.6175 -0.0365 0.0874  -0.0528 9   DC  D N4    
505  C C5    . DC  B 9  ? 0.7746 0.7297 0.6492 -0.0267 0.0907  -0.0463 9   DC  D C5    
506  C C6    . DC  B 9  ? 0.7093 0.6651 0.5755 -0.0145 0.0931  -0.0408 9   DC  D C6    
507  P P     . DC  B 10 ? 0.9763 1.0578 0.8387 0.0348  0.0916  0.0081  10  DC  D P     
508  O OP1   . DC  B 10 ? 0.9020 1.0310 0.7682 0.0524  0.0930  0.0304  10  DC  D OP1   
509  O OP2   . DC  B 10 ? 1.0804 1.1306 0.9273 0.0316  0.0950  0.0024  10  DC  D OP2   
510  O "O5'" . DC  B 10 ? 0.9109 1.0105 0.7890 0.0090  0.0795  -0.0080 10  DC  D "O5'" 
511  C "C5'" . DC  B 10 ? 0.8920 1.0186 0.7844 0.0041  0.0747  -0.0066 10  DC  D "C5'" 
512  C "C4'" . DC  B 10 ? 0.8620 0.9918 0.7575 -0.0223 0.0669  -0.0231 10  DC  D "C4'" 
513  O "O4'" . DC  B 10 ? 0.8327 0.9194 0.7276 -0.0270 0.0709  -0.0375 10  DC  D "O4'" 
514  C "C3'" . DC  B 10 ? 0.9167 1.0579 0.8005 -0.0379 0.0623  -0.0281 10  DC  D "C3'" 
515  O "O3'" . DC  B 10 ? 0.9596 1.1332 0.8418 -0.0601 0.0545  -0.0302 10  DC  D "O3'" 
516  C "C2'" . DC  B 10 ? 0.9497 1.0454 0.8258 -0.0449 0.0673  -0.0445 10  DC  D "C2'" 
517  C "C1'" . DC  B 10 ? 0.8257 0.9006 0.7123 -0.0432 0.0702  -0.0501 10  DC  D "C1'" 
518  N N1    . DC  B 10 ? 0.8181 0.8575 0.7052 -0.0389 0.0766  -0.0563 10  DC  D N1    
519  C C2    . DC  B 10 ? 0.7385 0.7605 0.6287 -0.0458 0.0802  -0.0653 10  DC  D C2    
520  O O2    . DC  B 10 ? 0.8721 0.8971 0.7585 -0.0574 0.0796  -0.0712 10  DC  D O2    
521  N N3    . DC  B 10 ? 0.7561 0.7595 0.6506 -0.0409 0.0854  -0.0657 10  DC  D N3    
522  C C4    . DC  B 10 ? 0.8442 0.8424 0.7366 -0.0348 0.0861  -0.0600 10  DC  D C4    
523  N N4    . DC  B 10 ? 0.8105 0.7992 0.7066 -0.0352 0.0898  -0.0585 10  DC  D N4    
524  C C5    . DC  B 10 ? 0.7301 0.7343 0.6143 -0.0286 0.0841  -0.0534 10  DC  D C5    
525  C C6    . DC  B 10 ? 0.7522 0.7786 0.6355 -0.0284 0.0800  -0.0508 10  DC  D C6    
526  P P     . DG  B 11 ? 1.0141 1.2166 0.8787 -0.0818 0.0476  -0.0305 11  DG  D P     
527  O OP1   . DG  B 11 ? 0.9240 1.1831 0.7927 -0.0986 0.0381  -0.0203 11  DG  D OP1   
528  O OP2   . DG  B 11 ? 1.0254 1.2325 0.8860 -0.0660 0.0495  -0.0211 11  DG  D OP2   
529  O "O5'" . DG  B 11 ? 0.9966 1.1463 0.8414 -0.1010 0.0532  -0.0537 11  DG  D "O5'" 
530  C "C5'" . DG  B 11 ? 1.0529 1.1806 0.8988 -0.1106 0.0562  -0.0638 11  DG  D "C5'" 
531  C "C4'" . DG  B 11 ? 1.1201 1.1961 0.9413 -0.1237 0.0662  -0.0817 11  DG  D "C4'" 
532  O "O4'" . DG  B 11 ? 1.1091 1.1502 0.9419 -0.1017 0.0755  -0.0838 11  DG  D "O4'" 
533  C "C3'" . DG  B 11 ? 1.1423 1.2103 0.9338 -0.1389 0.0676  -0.0876 11  DG  D "C3'" 
534  O "O3'" . DG  B 11 ? 1.1613 1.1852 0.9191 -0.1602 0.0778  -0.1033 11  DG  D "O3'" 
535  C "C2'" . DG  B 11 ? 1.0781 1.1247 0.8783 -0.1147 0.0745  -0.0857 11  DG  D "C2'" 
536  C "C1'" . DG  B 11 ? 1.0339 1.0525 0.8506 -0.0998 0.0824  -0.0882 11  DG  D "C1'" 
537  N N9    . DG  B 11 ? 0.9233 0.9373 0.7595 -0.0771 0.0848  -0.0812 11  DG  D N9    
538  C C8    . DG  B 11 ? 0.8374 0.8676 0.6844 -0.0635 0.0806  -0.0710 11  DG  D C8    
539  N N7    . DG  B 11 ? 0.8762 0.8897 0.7330 -0.0513 0.0857  -0.0686 11  DG  D N7    
540  C C5    . DG  B 11 ? 0.7645 0.7579 0.6220 -0.0538 0.0930  -0.0752 11  DG  D C5    
541  C C6    . DG  B 11 ? 0.8721 0.8532 0.7402 -0.0453 0.0998  -0.0726 11  DG  D C6    
542  O O6    . DG  B 11 ? 0.8876 0.8720 0.7645 -0.0390 0.0993  -0.0657 11  DG  D O6    
543  N N1    . DG  B 11 ? 0.8658 0.8301 0.7299 -0.0466 0.1089  -0.0774 11  DG  D N1    
544  C C2    . DG  B 11 ? 0.9818 0.9327 0.8278 -0.0582 0.1118  -0.0864 11  DG  D C2    
545  N N2    . DG  B 11 ? 1.1124 1.0383 0.9503 -0.0565 0.1243  -0.0896 11  DG  D N2    
546  N N3    . DG  B 11 ? 0.9753 0.9384 0.8093 -0.0722 0.1035  -0.0905 11  DG  D N3    
547  C C4    . DG  B 11 ? 0.8692 0.8573 0.7123 -0.0676 0.0941  -0.0834 11  DG  D C4    
548  P P     . DT  B 12 ? 1.2627 1.2649 0.9738 -0.1858 0.0826  -0.1137 12  DT  D P     
549  O OP1   . DT  B 12 ? 1.2342 1.2329 0.9174 -0.2207 0.0809  -0.1216 12  DT  D OP1   
550  O OP2   . DT  B 12 ? 1.1302 1.1750 0.8482 -0.1822 0.0718  -0.1032 12  DT  D OP2   
551  O "O5'" . DT  B 12 ? 1.1722 1.1081 0.8684 -0.1688 0.1040  -0.1231 12  DT  D "O5'" 
552  C "C5'" . DT  B 12 ? 1.2651 1.1638 0.9601 -0.1633 0.1163  -0.1283 12  DT  D "C5'" 
553  C "C4'" . DT  B 12 ? 1.3184 1.1811 1.0183 -0.1350 0.1338  -0.1266 12  DT  D "C4'" 
554  O "O4'" . DT  B 12 ? 1.2585 1.1577 1.0034 -0.1102 0.1244  -0.1140 12  DT  D "O4'" 
555  C "C3'" . DT  B 12 ? 1.4056 1.2333 1.0681 -0.1372 0.1480  -0.1324 12  DT  D "C3'" 
556  O "O3'" . DT  B 12 ? 1.5003 1.2630 1.1200 -0.1403 0.1725  -0.1414 12  DT  D "O3'" 
557  C "C2'" . DT  B 12 ? 1.3036 1.1475 0.9991 -0.1066 0.1495  -0.1208 12  DT  D "C2'" 
558  C "C1'" . DT  B 12 ? 1.1824 1.0589 0.9247 -0.0914 0.1388  -0.1111 12  DT  D "C1'" 
559  N N1    . DT  B 12 ? 0.9720 0.8832 0.7477 -0.0754 0.1286  -0.0999 12  DT  D N1    
560  C C2    . DT  B 12 ? 1.0384 0.9499 0.8363 -0.0555 0.1356  -0.0909 12  DT  D C2    
561  O O2    . DT  B 12 ? 1.1274 1.0186 0.9235 -0.0465 0.1493  -0.0894 12  DT  D O2    
562  N N3    . DT  B 12 ? 0.9616 0.8993 0.7813 -0.0473 0.1268  -0.0819 12  DT  D N3    
563  C C4    . DT  B 12 ? 0.9349 0.8930 0.7562 -0.0520 0.1145  -0.0803 12  DT  D C4    
564  O O4    . DT  B 12 ? 0.9647 0.9355 0.8001 -0.0441 0.1107  -0.0721 12  DT  D O4    
565  C C5    . DT  B 12 ? 0.8852 0.8484 0.6874 -0.0677 0.1082  -0.0870 12  DT  D C5    
566  C C7    . DT  B 12 ? 0.9461 0.9390 0.7505 -0.0694 0.0962  -0.0807 12  DT  D C7    
567  C C6    . DT  B 12 ? 0.8478 0.7898 0.6282 -0.0813 0.1143  -0.0968 12  DT  D C6    
568  P P     . DT  B 13 ? 1.5383 1.2449 1.1027 -0.1441 0.1949  -0.1494 13  DT  D P     
569  O OP1   . DT  B 13 ? 1.5845 1.2194 1.0846 -0.1657 0.2166  -0.1634 13  DT  D OP1   
570  O OP2   . DT  B 13 ? 1.4006 1.1426 0.9641 -0.1575 0.1786  -0.1496 13  DT  D OP2   
571  O "O5'" . DT  B 13 ? 1.4321 1.1322 1.0252 -0.1013 0.2118  -0.1356 13  DT  D "O5'" 
572  C "C5'" . DT  B 13 ? 1.2959 1.0056 0.9240 -0.0803 0.2147  -0.1259 13  DT  D "C5'" 
573  C "C4'" . DT  B 13 ? 1.3029 1.0349 0.9665 -0.0458 0.2221  -0.1084 13  DT  D "C4'" 
574  O "O4'" . DT  B 13 ? 1.0972 0.8907 0.8082 -0.0437 0.1970  -0.1007 13  DT  D "O4'" 
575  C "C3'" . DT  B 13 ? 1.2692 0.9692 0.9023 -0.0320 0.2450  -0.1055 13  DT  D "C3'" 
576  O "O3'" . DT  B 13 ? 1.2479 0.9504 0.8998 0.0019  0.2645  -0.0870 13  DT  D "O3'" 
577  C "C2'" . DT  B 13 ? 1.2000 0.9470 0.8586 -0.0356 0.2247  -0.1023 13  DT  D "C2'" 
578  C "C1'" . DT  B 13 ? 1.0410 0.8435 0.7561 -0.0292 0.2033  -0.0922 13  DT  D "C1'" 
579  N N1    . DT  B 13 ? 0.9824 0.8287 0.7222 -0.0368 0.1802  -0.0903 13  DT  D N1    
580  C C2    . DT  B 13 ? 1.0063 0.8899 0.7837 -0.0231 0.1730  -0.0764 13  DT  D C2    
581  O O2    . DT  B 13 ? 0.9510 0.8444 0.7478 -0.0070 0.1816  -0.0641 13  DT  D O2    
582  N N3    . DT  B 13 ? 0.9747 0.8853 0.7635 -0.0306 0.1558  -0.0757 13  DT  D N3    
583  C C4    . DT  B 13 ? 0.9568 0.8696 0.7292 -0.0462 0.1448  -0.0843 13  DT  D C4    
584  O O4    . DT  B 13 ? 0.9184 0.8558 0.7028 -0.0471 0.1324  -0.0796 13  DT  D O4    
585  C C5    . DT  B 13 ? 0.9954 0.8799 0.7328 -0.0622 0.1504  -0.0971 13  DT  D C5    
586  C C7    . DT  B 13 ? 0.9348 0.8320 0.6531 -0.0834 0.1375  -0.1037 13  DT  D C7    
587  C C6    . DT  B 13 ? 1.0390 0.8873 0.7590 -0.0585 0.1680  -0.1008 13  DT  D C6    
588  P P     . DT  B 14 ? 1.3746 1.0309 0.9887 0.0268  0.3009  -0.0786 14  DT  D P     
589  O OP1   . DT  B 14 ? 1.4475 1.0718 1.0510 0.0532  0.3298  -0.0664 14  DT  D OP1   
590  O OP2   . DT  B 14 ? 1.3429 0.9504 0.8997 0.0022  0.3059  -0.0981 14  DT  D OP2   
591  O "O5'" . DT  B 14 ? 1.3520 1.0785 1.0214 0.0465  0.2898  -0.0578 14  DT  D "O5'" 
592  C "C5'" . DT  B 14 ? 1.2444 1.0237 0.9655 0.0607  0.2807  -0.0400 14  DT  D "C5'" 
593  C "C4'" . DT  B 14 ? 1.2928 1.1314 1.0523 0.0712  0.2723  -0.0218 14  DT  D "C4'" 
594  O "O4'" . DT  B 14 ? 1.1382 1.0051 0.9140 0.0470  0.2426  -0.0325 14  DT  D "O4'" 
595  C "C3'" . DT  B 14 ? 1.2970 1.1222 1.0356 0.0912  0.2969  -0.0109 14  DT  D "C3'" 
596  O "O3'" . DT  B 14 ? 1.2274 1.1165 1.0092 0.1094  0.2968  0.0163  14  DT  D "O3'" 
597  C "C2'" . DT  B 14 ? 1.2300 1.0519 0.9556 0.0686  0.2804  -0.0270 14  DT  D "C2'" 
598  C "C1'" . DT  B 14 ? 1.1074 0.9800 0.8754 0.0495  0.2463  -0.0292 14  DT  D "C1'" 
599  N N1    . DT  B 14 ? 0.9954 0.8666 0.7550 0.0244  0.2244  -0.0466 14  DT  D N1    
600  C C2    . DT  B 14 ? 0.9506 0.8654 0.7405 0.0170  0.2038  -0.0409 14  DT  D C2    
601  O O2    . DT  B 14 ? 0.9644 0.9173 0.7846 0.0247  0.2015  -0.0245 14  DT  D O2    
602  N N3    . DT  B 14 ? 0.9466 0.8595 0.7265 -0.0007 0.1873  -0.0535 14  DT  D N3    
603  C C4    . DT  B 14 ? 1.0008 0.8835 0.7473 -0.0149 0.1864  -0.0697 14  DT  D C4    
604  O O4    . DT  B 14 ? 0.9827 0.8779 0.7267 -0.0283 0.1708  -0.0752 14  DT  D O4    
605  C C5    . DT  B 14 ? 1.0732 0.9101 0.7856 -0.0131 0.2067  -0.0772 14  DT  D C5    
606  C C7    . DT  B 14 ? 1.0860 0.8877 0.7533 -0.0362 0.2065  -0.0953 14  DT  D C7    
607  C C6    . DT  B 14 ? 1.0393 0.8675 0.7581 0.0080  0.2261  -0.0658 14  DT  D C6    
608  P P     . DA  B 15 ? 1.2508 1.1478 1.0265 0.1435  0.3288  0.0421  15  DA  D P     
609  O OP1   . DA  B 15 ? 1.2346 1.1899 1.0496 0.1668  0.3360  0.0736  15  DA  D OP1   
610  O OP2   . DA  B 15 ? 1.2967 1.1068 1.0097 0.1516  0.3582  0.0274  15  DA  D OP2   
611  O "O5'" . DA  B 15 ? 1.1794 1.1198 0.9737 0.1329  0.3134  0.0464  15  DA  D "O5'" 
612  C "C5'" . DA  B 15 ? 1.1375 1.1502 0.9796 0.1175  0.2861  0.0575  15  DA  D "C5'" 
613  C "C4'" . DA  B 15 ? 1.1164 1.1355 0.9554 0.0984  0.2705  0.0477  15  DA  D "C4'" 
614  O "O4'" . DA  B 15 ? 1.1482 1.1200 0.9613 0.0764  0.2560  0.0177  15  DA  D "O4'" 
615  C "C3'" . DA  B 15 ? 1.2176 1.2253 1.0356 0.1171  0.2941  0.0570  15  DA  D "C3'" 
616  O "O3'" . DA  B 15 ? 1.2771 1.3352 1.1183 0.1075  0.2816  0.0686  15  DA  D "O3'" 
617  C "C2'" . DA  B 15 ? 1.2334 1.1721 1.0047 0.1045  0.2952  0.0278  15  DA  D "C2'" 
618  C "C1'" . DA  B 15 ? 1.1598 1.1114 0.9478 0.0739  0.2610  0.0107  15  DA  D "C1'" 
619  N N9    . DA  B 15 ? 1.1366 1.0402 0.8900 0.0551  0.2531  -0.0157 15  DA  D N9    
620  C C8    . DA  B 15 ? 1.1742 1.0180 0.8825 0.0534  0.2682  -0.0316 15  DA  D C8    
621  N N7    . DA  B 15 ? 1.1477 0.9739 0.8353 0.0287  0.2522  -0.0515 15  DA  D N7    
622  C C5    . DA  B 15 ? 0.9991 0.8719 0.7196 0.0194  0.2282  -0.0473 15  DA  D C5    
623  C C6    . DA  B 15 ? 0.9783 0.8617 0.6975 -0.0004 0.2063  -0.0576 15  DA  D C6    
624  N N6    . DA  B 15 ? 0.9874 0.8461 0.6748 -0.0181 0.2013  -0.0738 15  DA  D N6    
625  N N1    . DA  B 15 ? 0.9328 0.8546 0.6816 -0.0023 0.1908  -0.0485 15  DA  D N1    
626  C C2    . DA  B 15 ? 0.8473 0.7981 0.6241 0.0088  0.1947  -0.0316 15  DA  D C2    
627  N N3    . DA  B 15 ? 0.9252 0.8817 0.7113 0.0256  0.2116  -0.0190 15  DA  D N3    
628  C C4    . DA  B 15 ? 0.9886 0.9035 0.7458 0.0333  0.2291  -0.0271 15  DA  D C4    
629  P P     . DG  B 16 ? 1.2551 1.3866 1.1304 0.1260  0.2933  0.1065  16  DG  D P     
630  O OP1   . DG  B 16 ? 1.1808 1.3587 1.0899 0.1197  0.2805  0.1189  16  DG  D OP1   
631  O OP2   . DG  B 16 ? 1.4012 1.5075 1.2523 0.1628  0.3308  0.1204  16  DG  D OP2   
632  O "O5'" . DG  B 16 ? 1.2297 1.3911 1.1151 0.0999  0.2723  0.1043  16  DG  D "O5'" 
633  C "C5'" . DG  B 16 ? 1.1684 1.3664 1.0785 0.0689  0.2432  0.1029  16  DG  D "C5'" 
634  C "C4'" . DG  B 16 ? 1.0942 1.2764 0.9917 0.0442  0.2260  0.0869  16  DG  D "C4'" 
635  O "O4'" . DG  B 16 ? 1.0192 1.1369 0.8859 0.0435  0.2244  0.0589  16  DG  D "O4'" 
636  C "C3'" . DG  B 16 ? 1.0858 1.2921 0.9821 0.0484  0.2356  0.1015  16  DG  D "C3'" 
637  O "O3'" . DG  B 16 ? 1.1004 1.3219 0.9999 0.0177  0.2149  0.0984  16  DG  D "O3'" 
638  C "C2'" . DG  B 16 ? 1.1216 1.2667 0.9822 0.0631  0.2495  0.0832  16  DG  D "C2'" 
639  C "C1'" . DG  B 16 ? 1.0004 1.1008 0.8464 0.0457  0.2311  0.0549  16  DG  D "C1'" 
640  N N9    . DG  B 16 ? 1.0277 1.0691 0.8401 0.0526  0.2394  0.0338  16  DG  D N9    
641  C C8    . DG  B 16 ? 1.1360 1.1465 0.9324 0.0707  0.2587  0.0317  16  DG  D C8    
642  N N7    . DG  B 16 ? 1.1751 1.1324 0.9370 0.0629  0.2583  0.0084  16  DG  D N7    
643  C C5    . DG  B 16 ? 1.0592 1.0209 0.8203 0.0415  0.2362  -0.0032 16  DG  D C5    
644  C C6    . DG  B 16 ? 1.1571 1.0873 0.8912 0.0249  0.2250  -0.0244 16  DG  D C6    
645  O O6    . DG  B 16 ? 1.1401 1.0299 0.8419 0.0204  0.2314  -0.0394 16  DG  D O6    
646  N N1    . DG  B 16 ? 1.1054 1.0570 0.8503 0.0109  0.2052  -0.0254 16  DG  D N1    
647  C C2    . DG  B 16 ? 1.0365 1.0240 0.8076 0.0094  0.1982  -0.0109 16  DG  D C2    
648  N N2    . DG  B 16 ? 1.0047 0.9974 0.7743 -0.0029 0.1833  -0.0139 16  DG  D N2    
649  N N3    . DG  B 16 ? 1.0029 1.0210 0.7973 0.0187  0.2067  0.0072  16  DG  D N3    
650  C C4    . DG  B 16 ? 1.0661 1.0738 0.8567 0.0362  0.2253  0.0113  16  DG  D C4    
656  N N     . PRO C 2  ? 1.8121 1.6741 2.2107 0.2871  0.0448  0.2110  232 PRO A N     
657  C CA    . PRO C 2  ? 1.5249 1.4257 1.9928 0.2887  0.0724  0.1834  232 PRO A CA    
658  C C     . PRO C 2  ? 1.4148 1.3274 1.8457 0.2583  0.1002  0.1454  232 PRO A C     
659  O O     . PRO C 2  ? 1.6363 1.5667 2.1165 0.2593  0.1309  0.1231  232 PRO A O     
660  C CB    . PRO C 2  ? 1.4940 1.4593 2.0281 0.3027  0.0306  0.2028  232 PRO A CB    
661  C CG    . PRO C 2  ? 1.6167 1.5616 2.1544 0.3272  -0.0075 0.2456  232 PRO A CG    
662  C CD    . PRO C 2  ? 1.7597 1.6448 2.1860 0.3077  -0.0057 0.2500  232 PRO A CD    
663  N N     . ARG C 3  ? 1.2470 1.1499 1.5948 0.2323  0.0901  0.1391  233 ARG A N     
664  C CA    . ARG C 3  ? 1.1830 1.0872 1.4888 0.2055  0.1142  0.1074  233 ARG A CA    
665  C C     . ARG C 3  ? 1.0654 1.0225 1.3973 0.1968  0.1066  0.0972  233 ARG A C     
666  O O     . ARG C 3  ? 0.9945 0.9825 1.3993 0.2107  0.1115  0.0973  233 ARG A O     
667  C CB    . ARG C 3  ? 1.1535 1.0252 1.4632 0.2016  0.1612  0.0810  233 ARG A CB    
668  C CG    . ARG C 3  ? 1.0549 0.9269 1.3117 0.1729  0.1782  0.0524  233 ARG A CG    
669  C CD    . ARG C 3  ? 1.0534 0.8793 1.2822 0.1622  0.2142  0.0297  233 ARG A CD    
670  N NE    . ARG C 3  ? 1.0635 0.8940 1.2322 0.1343  0.2143  0.0106  233 ARG A NE    
671  C CZ    . ARG C 3  ? 1.1513 0.9628 1.2674 0.1173  0.2083  0.0056  233 ARG A CZ    
672  N NH1   . ARG C 3  ? 1.1204 0.8948 1.2280 0.1194  0.2148  0.0098  233 ARG A NH1   
673  N NH2   . ARG C 3  ? 1.1204 0.9495 1.1963 0.0980  0.1972  -0.0037 233 ARG A NH2   
674  N N     . LYS C 4  ? 1.0324 0.9982 1.3089 0.1736  0.0978  0.0875  234 LYS A N     
675  C CA    . LYS C 4  ? 1.1019 1.1117 1.3944 0.1635  0.0859  0.0822  234 LYS A CA    
676  C C     . LYS C 4  ? 0.9775 0.9856 1.2559 0.1471  0.1188  0.0559  234 LYS A C     
677  O O     . LYS C 4  ? 0.8012 0.7763 1.0368 0.1380  0.1397  0.0425  234 LYS A O     
678  C CB    . LYS C 4  ? 1.2761 1.2943 1.5226 0.1521  0.0502  0.0945  234 LYS A CB    
679  C CG    . LYS C 4  ? 1.4228 1.4376 1.6120 0.1286  0.0530  0.0801  234 LYS A CG    
680  C CD    . LYS C 4  ? 1.6344 1.6825 1.8416 0.1164  0.0537  0.0691  234 LYS A CD    
681  C CE    . LYS C 4  ? 1.6869 1.7742 1.9347 0.1180  0.0256  0.0794  234 LYS A CE    
682  N NZ    . LYS C 4  ? 1.6571 1.7391 1.8641 0.1130  -0.0072 0.0933  234 LYS A NZ    
683  N N     . ALA C 5  ? 1.0164 1.0605 1.3300 0.1415  0.1210  0.0495  235 ALA A N     
684  C CA    . ALA C 5  ? 0.9025 0.9463 1.2104 0.1270  0.1538  0.0280  235 ALA A CA    
685  C C     . ALA C 5  ? 0.8901 0.9071 1.1168 0.1073  0.1562  0.0191  235 ALA A C     
686  O O     . ALA C 5  ? 1.0725 1.0926 1.2641 0.1000  0.1307  0.0272  235 ALA A O     
687  C CB    . ALA C 5  ? 0.8823 0.9689 1.2360 0.1211  0.1498  0.0266  235 ALA A CB    
688  N N     . ARG C 6  ? 0.7252 0.7162 0.9240 0.0982  0.1872  0.0018  236 ARG A N     
689  C CA    . ARG C 6  ? 0.7869 0.7562 0.9143 0.0802  0.1868  -0.0056 236 ARG A CA    
690  C C     . ARG C 6  ? 0.8171 0.8027 0.9310 0.0676  0.1814  -0.0043 236 ARG A C     
691  O O     . ARG C 6  ? 0.8681 0.8650 1.0092 0.0638  0.2017  -0.0107 236 ARG A O     
692  C CB    . ARG C 6  ? 0.8197 0.7580 0.9175 0.0704  0.2195  -0.0252 236 ARG A CB    
693  C CG    . ARG C 6  ? 0.8310 0.7522 0.8565 0.0508  0.2138  -0.0311 236 ARG A CG    
694  C CD    . ARG C 6  ? 0.8889 0.7772 0.8795 0.0411  0.2345  -0.0492 236 ARG A CD    
695  N NE    . ARG C 6  ? 0.8525 0.7277 0.7743 0.0213  0.2252  -0.0541 236 ARG A NE    
696  C CZ    . ARG C 6  ? 0.9014 0.7595 0.7858 0.0109  0.2179  -0.0630 236 ARG A CZ    
697  N NH1   . ARG C 6  ? 0.8839 0.7294 0.7898 0.0167  0.2258  -0.0698 236 ARG A NH1   
698  N NH2   . ARG C 6  ? 0.9645 0.8186 0.7940 -0.0049 0.2010  -0.0634 236 ARG A NH2   
699  N N     . THR C 7  ? 0.7651 0.7508 0.8430 0.0613  0.1573  0.0036  237 THR A N     
700  C CA    . THR C 7  ? 0.7742 0.7678 0.8388 0.0498  0.1544  0.0056  237 THR A CA    
701  C C     . THR C 7  ? 0.7719 0.7405 0.7880 0.0361  0.1746  -0.0030 237 THR A C     
702  O O     . THR C 7  ? 0.8162 0.7640 0.7917 0.0327  0.1736  -0.0073 237 THR A O     
703  C CB    . THR C 7  ? 0.8361 0.8323 0.8801 0.0489  0.1262  0.0156  237 THR A CB    
704  O OG1   . THR C 7  ? 0.8248 0.8432 0.9062 0.0563  0.1091  0.0230  237 THR A OG1   
705  C CG2   . THR C 7  ? 0.8452 0.8375 0.8666 0.0373  0.1253  0.0176  237 THR A CG2   
706  N N     . ALA C 8  ? 0.7814 0.7508 0.7990 0.0260  0.1927  -0.0057 238 ALA A N     
707  C CA    . ALA C 8  ? 0.9182 0.8582 0.8747 0.0107  0.2069  -0.0085 238 ALA A CA    
708  C C     . ALA C 8  ? 0.8408 0.7779 0.7756 0.0055  0.1893  0.0045  238 ALA A C     
709  O O     . ALA C 8  ? 0.8278 0.7775 0.7921 0.0016  0.1953  0.0066  238 ALA A O     
710  C CB    . ALA C 8  ? 0.9124 0.8440 0.8754 0.0002  0.2472  -0.0209 238 ALA A CB    
711  N N     . PHE C 9  ? 0.8568 0.7798 0.7494 0.0064  0.1672  0.0126  239 PHE A N     
712  C CA    . PHE C 9  ? 0.8617 0.7799 0.7429 0.0058  0.1509  0.0255  239 PHE A CA    
713  C C     . PHE C 9  ? 0.8986 0.7901 0.7407 -0.0075 0.1683  0.0308  239 PHE A C     
714  O O     . PHE C 9  ? 0.9069 0.7798 0.7117 -0.0164 0.1848  0.0256  239 PHE A O     
715  C CB    . PHE C 9  ? 0.9205 0.8330 0.7772 0.0123  0.1248  0.0327  239 PHE A CB    
716  C CG    . PHE C 9  ? 0.8452 0.7782 0.7345 0.0228  0.1111  0.0282  239 PHE A CG    
717  C CD1   . PHE C 9  ? 0.8658 0.8144 0.7895 0.0279  0.1039  0.0301  239 PHE A CD1   
718  C CD2   . PHE C 9  ? 0.8760 0.8083 0.7556 0.0244  0.1065  0.0217  239 PHE A CD2   
719  C CE1   . PHE C 9  ? 0.9457 0.9060 0.8882 0.0354  0.0932  0.0280  239 PHE A CE1   
720  C CE2   . PHE C 9  ? 1.0004 0.9450 0.9056 0.0322  0.0973  0.0193  239 PHE A CE2   
721  C CZ    . PHE C 9  ? 0.8683 0.8253 0.8021 0.0381  0.0911  0.0237  239 PHE A CZ    
722  N N     . SER C 10 ? 0.9963 0.8808 0.8420 -0.0106 0.1666  0.0403  240 SER A N     
723  C CA    . SER C 10 ? 1.0056 0.8559 0.8077 -0.0236 0.1832  0.0495  240 SER A CA    
724  C C     . SER C 10 ? 1.0202 0.8439 0.7663 -0.0192 0.1607  0.0659  240 SER A C     
725  O O     . SER C 10 ? 0.9643 0.8027 0.7227 -0.0063 0.1342  0.0683  240 SER A O     
726  C CB    . SER C 10 ? 0.9251 0.7727 0.7528 -0.0303 0.1924  0.0531  240 SER A CB    
727  O OG    . SER C 10 ? 1.0244 0.8691 0.8584 -0.0206 0.1688  0.0625  240 SER A OG    
728  N N     . ASP C 11 ? 0.9856 0.7710 0.6727 -0.0308 0.1720  0.0774  241 ASP A N     
729  C CA    . ASP C 11 ? 1.0694 0.8270 0.7004 -0.0270 0.1472  0.0982  241 ASP A CA    
730  C C     . ASP C 11 ? 1.0338 0.7943 0.6962 -0.0108 0.1239  0.1125  241 ASP A C     
731  O O     . ASP C 11 ? 1.1250 0.8851 0.7763 0.0011  0.0940  0.1254  241 ASP A O     
732  C CB    . ASP C 11 ? 1.1828 0.8909 0.7424 -0.0432 0.1656  0.1128  241 ASP A CB    
733  C CG    . ASP C 11 ? 1.2482 0.9390 0.7491 -0.0615 0.1862  0.1019  241 ASP A CG    
734  O OD1   . ASP C 11 ? 1.2512 0.9647 0.7578 -0.0592 0.1766  0.0866  241 ASP A OD1   
735  O OD2   . ASP C 11 ? 1.3611 1.0112 0.8078 -0.0797 0.2147  0.1078  241 ASP A OD2   
736  N N     . HIS C 12 ? 1.0209 0.7824 0.7226 -0.0122 0.1394  0.1095  242 HIS A N     
737  C CA    . HIS C 12 ? 1.0411 0.7979 0.7704 0.0005  0.1248  0.1193  242 HIS A CA    
738  C C     . HIS C 12 ? 0.9460 0.7422 0.7206 0.0142  0.1049  0.1074  242 HIS A C     
739  O O     . HIS C 12 ? 0.9462 0.7418 0.7309 0.0285  0.0847  0.1168  242 HIS A O     
740  C CB    . HIS C 12 ? 1.0521 0.7961 0.8066 -0.0093 0.1479  0.1153  242 HIS A CB    
741  C CG    . HIS C 12 ? 1.1444 0.8774 0.9256 0.0018  0.1384  0.1212  242 HIS A CG    
742  N ND1   . HIS C 12 ? 1.1967 0.8947 0.9568 0.0149  0.1260  0.1446  242 HIS A ND1   
743  C CD2   . HIS C 12 ? 1.0743 0.8249 0.9012 0.0018  0.1404  0.1057  242 HIS A CD2   
744  C CE1   . HIS C 12 ? 1.1283 0.8210 0.9255 0.0230  0.1263  0.1415  242 HIS A CE1   
745  N NE2   . HIS C 12 ? 1.0979 0.8206 0.9305 0.0130  0.1357  0.1167  242 HIS A NE2   
746  N N     . GLN C 13 ? 0.9070 0.7353 0.7103 0.0100  0.1121  0.0879  243 GLN A N     
747  C CA    . GLN C 13 ? 0.8530 0.7122 0.6905 0.0203  0.0967  0.0777  243 GLN A CA    
748  C C     . GLN C 13 ? 0.9184 0.7818 0.7376 0.0285  0.0760  0.0830  243 GLN A C     
749  O O     . GLN C 13 ? 0.9816 0.8529 0.8211 0.0398  0.0598  0.0864  243 GLN A O     
750  C CB    . GLN C 13 ? 0.7870 0.6738 0.6541 0.0154  0.1068  0.0609  243 GLN A CB    
751  C CG    . GLN C 13 ? 0.8023 0.6948 0.6994 0.0077  0.1172  0.0549  243 GLN A CG    
752  C CD    . GLN C 13 ? 0.7754 0.6948 0.7035 0.0017  0.1276  0.0428  243 GLN A CD    
753  O OE1   . GLN C 13 ? 0.8553 0.7810 0.7799 0.0023  0.1357  0.0389  243 GLN A OE1   
754  N NE2   . GLN C 13 ? 0.7216 0.6577 0.6829 -0.0040 0.1261  0.0361  243 GLN A NE2   
755  N N     . LEU C 14 ? 0.9611 0.8176 0.7419 0.0208  0.0780  0.0827  244 LEU A N     
756  C CA    . LEU C 14 ? 0.9113 0.7746 0.6727 0.0235  0.0564  0.0841  244 LEU A CA    
757  C C     . LEU C 14 ? 1.0093 0.8605 0.7607 0.0334  0.0323  0.1052  244 LEU A C     
758  O O     . LEU C 14 ? 0.9239 0.7937 0.6920 0.0417  0.0085  0.1070  244 LEU A O     
759  C CB    . LEU C 14 ? 0.9841 0.8343 0.6947 0.0089  0.0651  0.0780  244 LEU A CB    
760  C CG    . LEU C 14 ? 0.9610 0.8224 0.6876 0.0019  0.0902  0.0567  244 LEU A CG    
761  C CD1   . LEU C 14 ? 1.0092 0.8511 0.6816 -0.0139 0.1034  0.0474  244 LEU A CD1   
762  C CD2   . LEU C 14 ? 0.9337 0.8235 0.7054 0.0110  0.0806  0.0454  244 LEU A CD2   
763  N N     . ASN C 15 ? 1.0135 0.8326 0.7403 0.0324  0.0390  0.1221  245 ASN A N     
764  C CA    . ASN C 15 ? 1.1098 0.9128 0.8303 0.0452  0.0155  0.1464  245 ASN A CA    
765  C C     . ASN C 15 ? 1.0625 0.8872 0.8495 0.0625  0.0077  0.1433  245 ASN A C     
766  O O     . ASN C 15 ? 1.0963 0.9385 0.9055 0.0750  -0.0178 0.1503  245 ASN A O     
767  C CB    . ASN C 15 ? 1.1533 0.9093 0.8339 0.0413  0.0277  0.1671  245 ASN A CB    
768  C CG    . ASN C 15 ? 1.3020 1.0396 0.9829 0.0592  0.0009  0.1958  245 ASN A CG    
769  O OD1   . ASN C 15 ? 1.4698 1.2164 1.1315 0.0647  -0.0316 0.2084  245 ASN A OD1   
770  N ND2   . ASN C 15 ? 1.3167 1.0304 1.0247 0.0689  0.0125  0.2056  245 ASN A ND2   
771  N N     . GLN C 16 ? 1.0569 0.8821 0.8763 0.0612  0.0304  0.1307  246 GLN A N     
772  C CA    . GLN C 16 ? 1.0231 0.8569 0.8946 0.0740  0.0306  0.1265  246 GLN A CA    
773  C C     . GLN C 16 ? 0.9431 0.8154 0.8486 0.0778  0.0216  0.1106  246 GLN A C     
774  O O     . GLN C 16 ? 0.9873 0.8704 0.9325 0.0905  0.0142  0.1113  246 GLN A O     
775  C CB    . GLN C 16 ? 1.0282 0.8467 0.9116 0.0659  0.0565  0.1160  246 GLN A CB    
776  C CG    . GLN C 16 ? 0.9717 0.7469 0.8329 0.0628  0.0690  0.1316  246 GLN A CG    
777  C CD    . GLN C 16 ? 1.1100 0.8590 0.9869 0.0813  0.0606  0.1512  246 GLN A CD    
778  O OE1   . GLN C 16 ? 1.2625 0.9772 1.1093 0.0858  0.0551  0.1758  246 GLN A OE1   
779  N NE2   . GLN C 16 ? 1.1491 0.9099 1.0737 0.0926  0.0618  0.1414  246 GLN A NE2   
780  N N     . LEU C 17 ? 0.8919 0.7826 0.7847 0.0668  0.0246  0.0964  247 LEU A N     
781  C CA    . LEU C 17 ? 0.8893 0.8098 0.8075 0.0681  0.0175  0.0832  247 LEU A CA    
782  C C     . LEU C 17 ? 0.8737 0.8093 0.7961 0.0738  -0.0084 0.0910  247 LEU A C     
783  O O     . LEU C 17 ? 0.8308 0.7893 0.7947 0.0801  -0.0153 0.0849  247 LEU A O     
784  C CB    . LEU C 17 ? 0.8632 0.7925 0.7667 0.0564  0.0283  0.0685  247 LEU A CB    
785  C CG    . LEU C 17 ? 0.8787 0.8035 0.7883 0.0513  0.0474  0.0608  247 LEU A CG    
786  C CD1   . LEU C 17 ? 0.8937 0.8236 0.7892 0.0428  0.0564  0.0525  247 LEU A CD1   
787  C CD2   . LEU C 17 ? 0.8569 0.7915 0.7961 0.0542  0.0512  0.0516  247 LEU A CD2   
788  N N     . GLU C 18 ? 0.9548 0.8786 0.8335 0.0693  -0.0231 0.1034  248 GLU A N     
789  C CA    . GLU C 18 ? 0.9849 0.9238 0.8637 0.0733  -0.0553 0.1138  248 GLU A CA    
790  C C     . GLU C 18 ? 1.0071 0.9505 0.9340 0.0938  -0.0696 0.1303  248 GLU A C     
791  O O     . GLU C 18 ? 0.9756 0.9503 0.9464 0.1016  -0.0909 0.1302  248 GLU A O     
792  C CB    . GLU C 18 ? 1.1422 1.0588 0.9529 0.0642  -0.0713 0.1291  248 GLU A CB    
793  C CG    . GLU C 18 ? 1.2443 1.1603 1.0080 0.0432  -0.0638 0.1114  248 GLU A CG    
794  C CD    . GLU C 18 ? 1.2626 1.2135 1.0596 0.0382  -0.0721 0.0912  248 GLU A CD    
795  O OE1   . GLU C 18 ? 1.2245 1.1734 1.0085 0.0256  -0.0511 0.0711  248 GLU A OE1   
796  O OE2   . GLU C 18 ? 1.2594 1.2386 1.1009 0.0474  -0.0971 0.0957  248 GLU A OE2   
797  N N     . ARG C 19 ? 1.0121 0.9241 0.9364 0.1021  -0.0559 0.1430  249 ARG A N     
798  C CA    . ARG C 19 ? 0.9926 0.9007 0.9656 0.1235  -0.0634 0.1584  249 ARG A CA    
799  C C     . ARG C 19 ? 0.8980 0.8345 0.9404 0.1302  -0.0503 0.1387  249 ARG A C     
800  O O     . ARG C 19 ? 0.9330 0.8972 1.0299 0.1435  -0.0674 0.1421  249 ARG A O     
801  C CB    . ARG C 19 ? 1.0989 0.9602 1.0518 0.1269  -0.0437 0.1715  249 ARG A CB    
802  C CG    . ARG C 19 ? 1.2403 1.0704 1.1249 0.1216  -0.0587 0.1959  249 ARG A CG    
803  C CD    . ARG C 19 ? 1.3084 1.0862 1.1685 0.1231  -0.0392 0.2125  249 ARG A CD    
804  N NE    . ARG C 19 ? 1.3169 1.0722 1.1933 0.1460  -0.0600 0.2440  249 ARG A NE    
805  C CZ    . ARG C 19 ? 1.3412 1.0430 1.1766 0.1477  -0.0544 0.2695  249 ARG A CZ    
806  N NH1   . ARG C 19 ? 1.4363 1.1061 1.2174 0.1258  -0.0262 0.2637  249 ARG A NH1   
807  N NH2   . ARG C 19 ? 1.2877 0.9680 1.1397 0.1713  -0.0764 0.3016  249 ARG A NH2   
808  N N     . SER C 20 ? 1.0039 0.9352 1.0435 0.1192  -0.0204 0.1176  250 SER A N     
809  C CA    . SER C 20 ? 0.8748 0.8239 0.9644 0.1212  -0.0029 0.0983  250 SER A CA    
810  C C     . SER C 20 ? 0.8470 0.8373 0.9683 0.1205  -0.0199 0.0908  250 SER A C     
811  O O     . SER C 20 ? 0.8823 0.8938 1.0649 0.1312  -0.0198 0.0872  250 SER A O     
812  C CB    . SER C 20 ? 0.7981 0.7355 0.8638 0.1062  0.0234  0.0800  250 SER A CB    
813  O OG    . SER C 20 ? 0.9448 0.8995 1.0395 0.1024  0.0374  0.0611  250 SER A OG    
814  N N     . PHE C 21 ? 0.8637 0.8644 0.9463 0.1071  -0.0335 0.0881  251 PHE A N     
815  C CA    . PHE C 21 ? 0.8654 0.9020 0.9721 0.1006  -0.0475 0.0772  251 PHE A CA    
816  C C     . PHE C 21 ? 0.8736 0.9379 1.0280 0.1142  -0.0785 0.0907  251 PHE A C     
817  O O     . PHE C 21 ? 0.9196 1.0199 1.1292 0.1139  -0.0840 0.0799  251 PHE A O     
818  C CB    . PHE C 21 ? 0.8570 0.8921 0.9075 0.0832  -0.0569 0.0725  251 PHE A CB    
819  C CG    . PHE C 21 ? 0.8065 0.8731 0.8799 0.0716  -0.0647 0.0559  251 PHE A CG    
820  C CD1   . PHE C 21 ? 0.7147 0.7878 0.8147 0.0657  -0.0400 0.0374  251 PHE A CD1   
821  C CD2   . PHE C 21 ? 0.8794 0.9663 0.9448 0.0646  -0.0968 0.0589  251 PHE A CD2   
822  C CE1   . PHE C 21 ? 0.7901 0.8873 0.9122 0.0530  -0.0429 0.0218  251 PHE A CE1   
823  C CE2   . PHE C 21 ? 0.9165 1.0323 1.0070 0.0507  -0.1024 0.0408  251 PHE A CE2   
824  C CZ    . PHE C 21 ? 0.8269 0.9460 0.9461 0.0446  -0.0731 0.0219  251 PHE A CZ    
825  N N     . GLU C 22 ? 1.0601 1.1070 1.1904 0.1245  -0.1003 0.1156  252 GLU A N     
826  C CA    . GLU C 22 ? 1.0468 1.1154 1.2192 0.1415  -0.1362 0.1361  252 GLU A CA    
827  C C     . GLU C 22 ? 1.0232 1.1030 1.2834 0.1625  -0.1199 0.1344  252 GLU A C     
828  O O     . GLU C 22 ? 1.1266 1.2488 1.4607 0.1727  -0.1384 0.1346  252 GLU A O     
829  C CB    . GLU C 22 ? 1.1754 1.2082 1.2851 0.1465  -0.1574 0.1659  252 GLU A CB    
830  C CG    . GLU C 22 ? 1.2864 1.3355 1.4306 0.1668  -0.2016 0.1952  252 GLU A CG    
831  C CD    . GLU C 22 ? 1.3028 1.4050 1.4708 0.1590  -0.2430 0.1913  252 GLU A CD    
832  O OE1   . GLU C 22 ? 1.2493 1.3784 1.4673 0.1773  -0.2828 0.2132  252 GLU A OE1   
833  O OE2   . GLU C 22 ? 1.3084 1.4250 1.4469 0.1342  -0.2369 0.1666  252 GLU A OE2   
834  N N     . ARG C 23 ? 0.9346 0.9771 1.1887 0.1672  -0.0843 0.1309  253 ARG A N     
835  C CA    . ARG C 23 ? 0.9359 0.9789 1.2647 0.1841  -0.0599 0.1248  253 ARG A CA    
836  C C     . ARG C 23 ? 0.8547 0.9312 1.2307 0.1739  -0.0383 0.0957  253 ARG A C     
837  O O     . ARG C 23 ? 0.7522 0.8554 1.2116 0.1869  -0.0322 0.0904  253 ARG A O     
838  C CB    . ARG C 23 ? 0.9358 0.9277 1.2389 0.1849  -0.0237 0.1217  253 ARG A CB    
839  C CG    . ARG C 23 ? 1.0501 1.0028 1.3345 0.2007  -0.0346 0.1507  253 ARG A CG    
840  C CD    . ARG C 23 ? 1.1287 1.0314 1.4012 0.1997  0.0048  0.1432  253 ARG A CD    
841  N NE    . ARG C 23 ? 1.1855 1.0737 1.4030 0.1737  0.0307  0.1201  253 ARG A NE    
842  C CZ    . ARG C 23 ? 1.2115 1.0840 1.3601 0.1570  0.0269  0.1236  253 ARG A CZ    
843  N NH1   . ARG C 23 ? 1.2620 1.1225 1.3743 0.1602  0.0029  0.1484  253 ARG A NH1   
844  N NH2   . ARG C 23 ? 1.1198 0.9883 1.2365 0.1366  0.0476  0.1024  253 ARG A NH2   
845  N N     . GLN C 24 ? 0.8251 0.8985 1.1499 0.1506  -0.0248 0.0776  254 GLN A N     
846  C CA    . GLN C 24 ? 0.7474 0.8358 1.0996 0.1384  0.0037  0.0516  254 GLN A CA    
847  C C     . GLN C 24 ? 0.7327 0.8269 1.0345 0.1157  0.0012  0.0399  254 GLN A C     
848  O O     . GLN C 24 ? 0.7267 0.7931 0.9614 0.1060  0.0060  0.0410  254 GLN A O     
849  C CB    . GLN C 24 ? 0.7703 0.8187 1.1021 0.1360  0.0431  0.0410  254 GLN A CB    
850  C CG    . GLN C 24 ? 0.7912 0.8257 1.1778 0.1553  0.0608  0.0437  254 GLN A CG    
851  C CD    . GLN C 24 ? 0.8735 0.8687 1.2286 0.1436  0.1024  0.0253  254 GLN A CD    
852  O OE1   . GLN C 24 ? 0.9161 0.8735 1.2335 0.1439  0.1098  0.0306  254 GLN A OE1   
853  N NE2   . GLN C 24 ? 0.8848 0.8866 1.2435 0.1286  0.1284  0.0031  254 GLN A NE2   
854  N N     . LYS C 25 ? 0.6820 0.8119 1.0239 0.1072  -0.0023 0.0271  255 LYS A N     
855  C CA    . LYS C 25 ? 0.7993 0.9334 1.1031 0.0861  -0.0033 0.0152  255 LYS A CA    
856  C C     . LYS C 25 ? 0.7520 0.8587 1.0275 0.0740  0.0347  0.0000  255 LYS A C     
857  O O     . LYS C 25 ? 0.6899 0.7813 0.9152 0.0603  0.0385  -0.0045 255 LYS A O     
858  C CB    . LYS C 25 ? 0.7774 0.9591 1.1407 0.0799  -0.0213 0.0067  255 LYS A CB    
859  C CG    . LYS C 25 ? 0.8605 1.0694 1.2402 0.0900  -0.0682 0.0247  255 LYS A CG    
860  C CD    . LYS C 25 ? 0.8847 1.0970 1.2075 0.0725  -0.0974 0.0250  255 LYS A CD    
861  C CE    . LYS C 25 ? 0.9867 1.2293 1.3278 0.0802  -0.1470 0.0427  255 LYS A CE    
862  N NZ    . LYS C 25 ? 1.0048 1.2199 1.3201 0.1014  -0.1584 0.0701  255 LYS A NZ    
863  N N     . TYR C 26 ? 0.7012 0.7995 1.0085 0.0793  0.0628  -0.0069 256 TYR A N     
864  C CA    . TYR C 26 ? 0.6790 0.7456 0.9489 0.0674  0.0968  -0.0185 256 TYR A CA    
865  C C     . TYR C 26 ? 0.6488 0.6866 0.9072 0.0766  0.1118  -0.0153 256 TYR A C     
866  O O     . TYR C 26 ? 0.6137 0.6596 0.9168 0.0931  0.1061  -0.0085 256 TYR A O     
867  C CB    . TYR C 26 ? 0.6932 0.7722 1.0024 0.0557  0.1236  -0.0365 256 TYR A CB    
868  C CG    . TYR C 26 ? 0.7039 0.8078 1.0248 0.0424  0.1118  -0.0426 256 TYR A CG    
869  C CD1   . TYR C 26 ? 0.6638 0.8130 1.0434 0.0459  0.0847  -0.0421 256 TYR A CD1   
870  C CD2   . TYR C 26 ? 0.7863 0.8658 1.0575 0.0252  0.1266  -0.0486 256 TYR A CD2   
871  C CE1   . TYR C 26 ? 0.6362 0.8056 1.0227 0.0289  0.0753  -0.0516 256 TYR A CE1   
872  C CE2   . TYR C 26 ? 0.7853 0.8797 1.0647 0.0109  0.1207  -0.0562 256 TYR A CE2   
873  C CZ    . TYR C 26 ? 0.6812 0.8206 1.0176 0.0109  0.0963  -0.0599 256 TYR A CZ    
874  O OH    . TYR C 26 ? 0.6958 0.8430 1.0312 -0.0078 0.0938  -0.0707 256 TYR A OH    
875  N N     . LEU C 27 ? 0.6078 0.6123 0.8046 0.0657  0.1261  -0.0183 257 LEU A N     
876  C CA    . LEU C 27 ? 0.6939 0.6665 0.8652 0.0663  0.1418  -0.0199 257 LEU A CA    
877  C C     . LEU C 27 ? 0.7535 0.7022 0.9001 0.0504  0.1752  -0.0366 257 LEU A C     
878  O O     . LEU C 27 ? 0.6737 0.6186 0.7889 0.0374  0.1787  -0.0394 257 LEU A O     
879  C CB    . LEU C 27 ? 0.7340 0.6905 0.8487 0.0632  0.1249  -0.0092 257 LEU A CB    
880  C CG    . LEU C 27 ? 0.7159 0.6788 0.8350 0.0756  0.0998  0.0074  257 LEU A CG    
881  C CD1   . LEU C 27 ? 0.8164 0.7605 0.8828 0.0672  0.0957  0.0115  257 LEU A CD1   
882  C CD2   . LEU C 27 ? 0.6304 0.5877 0.7877 0.0915  0.1002  0.0146  257 LEU A CD2   
883  N N     . SER C 28 ? 0.8319 0.7573 0.9834 0.0505  0.1996  -0.0464 258 SER A N     
884  C CA    . SER C 28 ? 0.8701 0.7611 0.9743 0.0316  0.2299  -0.0620 258 SER A CA    
885  C C     . SER C 28 ? 0.8856 0.7581 0.9159 0.0200  0.2120  -0.0546 258 SER A C     
886  O O     . SER C 28 ? 0.9429 0.8266 0.9693 0.0282  0.1843  -0.0407 258 SER A O     
887  C CB    . SER C 28 ? 0.8414 0.7078 0.9668 0.0331  0.2621  -0.0773 258 SER A CB    
888  O OG    . SER C 28 ? 0.8168 0.6778 0.9549 0.0468  0.2475  -0.0677 258 SER A OG    
889  N N     . VAL C 29 ? 0.8751 0.7190 0.8485 0.0003  0.2289  -0.0641 259 VAL A N     
890  C CA    . VAL C 29 ? 0.9039 0.7304 0.8116 -0.0120 0.2123  -0.0590 259 VAL A CA    
891  C C     . VAL C 29 ? 0.8259 0.6467 0.7408 -0.0081 0.2061  -0.0604 259 VAL A C     
892  O O     . VAL C 29 ? 0.8096 0.6395 0.7112 -0.0066 0.1803  -0.0493 259 VAL A O     
893  C CB    . VAL C 29 ? 1.0979 0.8883 0.9380 -0.0359 0.2320  -0.0701 259 VAL A CB    
894  C CG1   . VAL C 29 ? 1.1204 0.8999 0.8975 -0.0483 0.2059  -0.0624 259 VAL A CG1   
895  C CG2   . VAL C 29 ? 1.0996 0.8869 0.9312 -0.0415 0.2457  -0.0687 259 VAL A CG2   
896  N N     . GLN C 30 ? 0.8054 0.6084 0.7447 -0.0070 0.2336  -0.0750 260 GLN A N     
897  C CA    . GLN C 30 ? 0.9152 0.7011 0.8526 -0.0076 0.2336  -0.0786 260 GLN A CA    
898  C C     . GLN C 30 ? 0.8326 0.6422 0.8098 0.0127  0.2073  -0.0588 260 GLN A C     
899  O O     . GLN C 30 ? 0.9423 0.7495 0.8974 0.0076  0.1905  -0.0527 260 GLN A O     
900  C CB    . GLN C 30 ? 0.9226 0.6759 0.8759 -0.0114 0.2741  -0.1003 260 GLN A CB    
901  C CG    . GLN C 30 ? 0.9917 0.7134 0.9247 -0.0212 0.2808  -0.1100 260 GLN A CG    
902  C CD    . GLN C 30 ? 1.1888 0.9057 1.0525 -0.0450 0.2581  -0.1106 260 GLN A CD    
903  O OE1   . GLN C 30 ? 1.2128 0.9296 1.0257 -0.0611 0.2520  -0.1128 260 GLN A OE1   
904  N NE2   . GLN C 30 ? 1.1432 0.8591 1.0082 -0.0464 0.2425  -0.1055 260 GLN A NE2   
905  N N     . ASP C 31 ? 0.7893 0.6212 0.8235 0.0337  0.2036  -0.0492 261 ASP A N     
906  C CA    . ASP C 31 ? 0.8585 0.7071 0.9175 0.0506  0.1780  -0.0291 261 ASP A CA    
907  C C     . ASP C 31 ? 0.8307 0.6962 0.8538 0.0446  0.1507  -0.0174 261 ASP A C     
908  O O     . ASP C 31 ? 0.7416 0.6065 0.7572 0.0472  0.1362  -0.0062 261 ASP A O     
909  C CB    . ASP C 31 ? 0.7616 0.6354 0.8827 0.0716  0.1722  -0.0201 261 ASP A CB    
910  C CG    . ASP C 31 ? 0.8553 0.7138 1.0282 0.0839  0.1974  -0.0276 261 ASP A CG    
911  O OD1   . ASP C 31 ? 0.9291 0.7515 1.0834 0.0766  0.2184  -0.0380 261 ASP A OD1   
912  O OD2   . ASP C 31 ? 0.8333 0.7168 1.0682 0.1002  0.1956  -0.0236 261 ASP A OD2   
913  N N     . ARG C 32 ? 0.6916 0.5691 0.6949 0.0365  0.1473  -0.0202 262 ARG A N     
914  C CA    . ARG C 32 ? 0.7795 0.6725 0.7595 0.0341  0.1247  -0.0095 262 ARG A CA    
915  C C     . ARG C 32 ? 0.8106 0.6924 0.7582 0.0226  0.1188  -0.0101 262 ARG A C     
916  O O     . ARG C 32 ? 0.7381 0.6306 0.6867 0.0256  0.1042  -0.0002 262 ARG A O     
917  C CB    . ARG C 32 ? 0.8238 0.7247 0.7888 0.0285  0.1239  -0.0108 262 ARG A CB    
918  C CG    . ARG C 32 ? 0.8753 0.7876 0.8213 0.0281  0.1038  -0.0002 262 ARG A CG    
919  C CD    . ARG C 32 ? 0.9651 0.8811 0.9037 0.0262  0.1040  0.0010  262 ARG A CD    
920  N NE    . ARG C 32 ? 1.0055 0.9003 0.9089 0.0135  0.1150  -0.0041 262 ARG A NE    
921  C CZ    . ARG C 32 ? 1.1904 1.0734 1.0913 0.0073  0.1350  -0.0122 262 ARG A CZ    
922  N NH1   . ARG C 32 ? 1.1912 1.0487 1.0462 -0.0066 0.1446  -0.0151 262 ARG A NH1   
923  N NH2   . ARG C 32 ? 1.2207 1.1177 1.1642 0.0136  0.1447  -0.0172 262 ARG A NH2   
924  N N     . MET C 33 ? 0.7643 0.6252 0.6841 0.0073  0.1315  -0.0233 263 MET A N     
925  C CA    . MET C 33 ? 0.8583 0.7129 0.7463 -0.0086 0.1226  -0.0269 263 MET A CA    
926  C C     . MET C 33 ? 0.9351 0.7812 0.8389 -0.0085 0.1254  -0.0274 263 MET A C     
927  O O     . MET C 33 ? 0.9230 0.7781 0.8206 -0.0166 0.1123  -0.0245 263 MET A O     
928  C CB    . MET C 33 ? 0.9332 0.7618 0.7793 -0.0290 0.1361  -0.0435 263 MET A CB    
929  C CG    . MET C 33 ? 1.0919 0.9205 0.9001 -0.0369 0.1293  -0.0407 263 MET A CG    
930  S SD    . MET C 33 ? 1.2532 1.0443 0.9925 -0.0663 0.1431  -0.0597 263 MET A SD    
931  C CE    . MET C 33 ? 1.2195 1.0095 0.9135 -0.0703 0.1294  -0.0457 263 MET A CE    
932  N N     . ASP C 34 ? 0.8494 0.6763 0.7765 0.0000  0.1445  -0.0313 264 ASP A N     
933  C CA    . ASP C 34 ? 0.8287 0.6387 0.7719 0.0030  0.1503  -0.0282 264 ASP A CA    
934  C C     . ASP C 34 ? 0.8583 0.6867 0.8172 0.0165  0.1327  -0.0077 264 ASP A C     
935  O O     . ASP C 34 ? 0.8603 0.6808 0.8147 0.0101  0.1315  -0.0040 264 ASP A O     
936  C CB    . ASP C 34 ? 0.9046 0.6906 0.8793 0.0165  0.1719  -0.0307 264 ASP A CB    
937  C CG    . ASP C 34 ? 0.9739 0.7284 0.9376 0.0034  0.2011  -0.0544 264 ASP A CG    
938  O OD1   . ASP C 34 ? 0.9061 0.6577 0.8264 -0.0188 0.2016  -0.0689 264 ASP A OD1   
939  O OD2   . ASP C 34 ? 0.9924 0.7242 0.9905 0.0159  0.2228  -0.0573 264 ASP A OD2   
940  N N     . LEU C 35 ? 0.7411 0.5909 0.7158 0.0321  0.1218  0.0035  265 LEU A N     
941  C CA    . LEU C 35 ? 0.8047 0.6677 0.7820 0.0407  0.1062  0.0205  265 LEU A CA    
942  C C     . LEU C 35 ? 0.8470 0.7257 0.8049 0.0287  0.0972  0.0198  265 LEU A C     
943  O O     . LEU C 35 ? 0.7781 0.6557 0.7321 0.0264  0.0951  0.0273  265 LEU A O     
944  C CB    . LEU C 35 ? 0.6847 0.5671 0.6797 0.0555  0.0951  0.0290  265 LEU A CB    
945  C CG    . LEU C 35 ? 0.7719 0.6632 0.7596 0.0619  0.0790  0.0448  265 LEU A CG    
946  C CD1   . LEU C 35 ? 0.7526 0.6215 0.7423 0.0704  0.0779  0.0600  265 LEU A CD1   
947  C CD2   . LEU C 35 ? 0.7564 0.6714 0.7583 0.0694  0.0670  0.0460  265 LEU A CD2   
948  N N     . ALA C 36 ? 0.8424 0.7333 0.7895 0.0203  0.0936  0.0109  266 ALA A N     
949  C CA    . ALA C 36 ? 0.8688 0.7776 0.8087 0.0117  0.0830  0.0114  266 ALA A CA    
950  C C     . ALA C 36 ? 0.8801 0.7821 0.8199 -0.0025 0.0867  0.0062  266 ALA A C     
951  O O     . ALA C 36 ? 0.8451 0.7593 0.7949 -0.0050 0.0843  0.0108  266 ALA A O     
952  C CB    . ALA C 36 ? 0.8865 0.8036 0.8117 0.0063  0.0757  0.0065  266 ALA A CB    
953  N N     . ALA C 37 ? 0.7735 0.6546 0.7029 -0.0140 0.0960  -0.0059 267 ALA A N     
954  C CA    . ALA C 37 ? 0.8576 0.7314 0.7859 -0.0329 0.0997  -0.0151 267 ALA A CA    
955  C C     . ALA C 37 ? 0.8151 0.6747 0.7572 -0.0296 0.1110  -0.0066 267 ALA A C     
956  O O     . ALA C 37 ? 0.9778 0.8442 0.9280 -0.0435 0.1120  -0.0095 267 ALA A O     
957  C CB    . ALA C 37 ? 0.8969 0.7426 0.8050 -0.0477 0.1118  -0.0328 267 ALA A CB    
958  N N     . ALA C 38 ? 0.7571 0.5971 0.7024 -0.0121 0.1186  0.0044  268 ALA A N     
959  C CA    . ALA C 38 ? 0.8643 0.6788 0.8122 -0.0085 0.1293  0.0161  268 ALA A CA    
960  C C     . ALA C 38 ? 0.7737 0.6053 0.7194 -0.0076 0.1237  0.0282  268 ALA A C     
961  O O     . ALA C 38 ? 0.8307 0.6410 0.7707 -0.0126 0.1349  0.0362  268 ALA A O     
962  C CB    . ALA C 38 ? 0.7677 0.5591 0.7223 0.0121  0.1330  0.0278  268 ALA A CB    
963  N N     . LEU C 39 ? 0.7190 0.5828 0.6667 -0.0019 0.1104  0.0291  269 LEU A N     
964  C CA    . LEU C 39 ? 0.7417 0.6205 0.6869 0.0000  0.1088  0.0372  269 LEU A CA    
965  C C     . LEU C 39 ? 0.7593 0.6701 0.7237 -0.0108 0.1062  0.0275  269 LEU A C     
966  O O     . LEU C 39 ? 0.9123 0.8368 0.8819 -0.0099 0.1099  0.0305  269 LEU A O     
967  C CB    . LEU C 39 ? 0.6869 0.5762 0.6251 0.0159  0.0969  0.0439  269 LEU A CB    
968  C CG    . LEU C 39 ? 0.7221 0.5914 0.6521 0.0294  0.0926  0.0555  269 LEU A CG    
969  C CD1   . LEU C 39 ? 0.7787 0.6672 0.7058 0.0387  0.0797  0.0579  269 LEU A CD1   
970  C CD2   . LEU C 39 ? 0.7763 0.6160 0.6874 0.0306  0.0978  0.0713  269 LEU A CD2   
971  N N     . ASN C 40 ? 0.6910 0.6137 0.6660 -0.0208 0.0992  0.0159  270 ASN A N     
972  C CA    . ASN C 40 ? 0.7031 0.6611 0.7021 -0.0285 0.0885  0.0095  270 ASN A CA    
973  C C     . ASN C 40 ? 0.7558 0.7351 0.7608 -0.0132 0.0782  0.0157  270 ASN A C     
974  O O     . ASN C 40 ? 0.8337 0.8388 0.8667 -0.0126 0.0774  0.0160  270 ASN A O     
975  C CB    . ASN C 40 ? 0.7682 0.7379 0.7936 -0.0419 0.1004  0.0063  270 ASN A CB    
976  C CG    . ASN C 40 ? 0.9473 0.9124 0.9803 -0.0641 0.1026  -0.0060 270 ASN A CG    
977  O OD1   . ASN C 40 ? 0.9976 0.9822 1.0370 -0.0733 0.0844  -0.0151 270 ASN A OD1   
978  N ND2   . ASN C 40 ? 1.0959 1.0321 1.1236 -0.0745 0.1242  -0.0061 270 ASN A ND2   
979  N N     . LEU C 41 ? 0.6918 0.6594 0.6757 -0.0016 0.0732  0.0194  271 LEU A N     
980  C CA    . LEU C 41 ? 0.6989 0.6801 0.6843 0.0096  0.0634  0.0232  271 LEU A CA    
981  C C     . LEU C 41 ? 0.8046 0.7849 0.7760 0.0066  0.0507  0.0204  271 LEU A C     
982  O O     . LEU C 41 ? 0.7645 0.7283 0.7187 -0.0024 0.0534  0.0136  271 LEU A O     
983  C CB    . LEU C 41 ? 0.6793 0.6464 0.6498 0.0208  0.0693  0.0281  271 LEU A CB    
984  C CG    . LEU C 41 ? 0.7272 0.6870 0.6939 0.0212  0.0806  0.0322  271 LEU A CG    
985  C CD1   . LEU C 41 ? 0.7394 0.6884 0.6874 0.0296  0.0790  0.0370  271 LEU A CD1   
986  C CD2   . LEU C 41 ? 0.7598 0.7380 0.7476 0.0192  0.0871  0.0300  271 LEU A CD2   
987  N N     . THR C 42 ? 0.7876 0.7806 0.7630 0.0137  0.0395  0.0258  272 THR A N     
988  C CA    . THR C 42 ? 0.7690 0.7534 0.7189 0.0113  0.0291  0.0268  272 THR A CA    
989  C C     . THR C 42 ? 0.7517 0.7141 0.6817 0.0164  0.0418  0.0250  272 THR A C     
990  O O     . THR C 42 ? 0.8242 0.7856 0.7647 0.0252  0.0506  0.0263  272 THR A O     
991  C CB    . THR C 42 ? 0.7238 0.7220 0.6829 0.0193  0.0135  0.0375  272 THR A CB    
992  O OG1   . THR C 42 ? 0.7420 0.7366 0.7121 0.0330  0.0247  0.0412  272 THR A OG1   
993  C CG2   . THR C 42 ? 0.7472 0.7764 0.7435 0.0179  -0.0009 0.0404  272 THR A CG2   
994  N N     . ASP C 43 ? 0.7467 0.6925 0.6477 0.0090  0.0425  0.0213  273 ASP A N     
995  C CA    . ASP C 43 ? 0.6950 0.6241 0.5845 0.0124  0.0559  0.0187  273 ASP A CA    
996  C C     . ASP C 43 ? 0.6117 0.5471 0.5139 0.0241  0.0556  0.0262  273 ASP A C     
997  O O     . ASP C 43 ? 0.6448 0.5792 0.5588 0.0290  0.0654  0.0231  273 ASP A O     
998  C CB    . ASP C 43 ? 0.8781 0.7868 0.7285 0.0008  0.0584  0.0153  273 ASP A CB    
999  C CG    . ASP C 43 ? 1.2009 1.0889 1.0393 -0.0083 0.0786  0.0006  273 ASP A CG    
1000 O OD1   . ASP C 43 ? 1.2335 1.1182 1.0721 -0.0162 0.0797  -0.0073 273 ASP A OD1   
1001 O OD2   . ASP C 43 ? 1.3750 1.2499 1.2092 -0.0079 0.0960  -0.0038 273 ASP A OD2   
1002 N N     . THR C 44 ? 0.6465 0.5873 0.5479 0.0279  0.0440  0.0358  274 THR A N     
1003 C CA    . THR C 44 ? 0.7135 0.6516 0.6235 0.0371  0.0480  0.0409  274 THR A CA    
1004 C C     . THR C 44 ? 0.7026 0.6525 0.6378 0.0434  0.0543  0.0367  274 THR A C     
1005 O O     . THR C 44 ? 0.7694 0.7147 0.7075 0.0453  0.0625  0.0330  274 THR A O     
1006 C CB    . THR C 44 ? 0.7349 0.6750 0.6479 0.0437  0.0347  0.0538  274 THR A CB    
1007 O OG1   . THR C 44 ? 0.6895 0.6152 0.5668 0.0350  0.0257  0.0590  274 THR A OG1   
1008 C CG2   . THR C 44 ? 0.8166 0.7447 0.7367 0.0525  0.0433  0.0582  274 THR A CG2   
1009 N N     . GLN C 45 ? 0.6674 0.6317 0.6182 0.0440  0.0507  0.0367  275 GLN A N     
1010 C CA    . GLN C 45 ? 0.6397 0.6092 0.6024 0.0472  0.0585  0.0336  275 GLN A CA    
1011 C C     . GLN C 45 ? 0.6387 0.6013 0.5919 0.0453  0.0624  0.0293  275 GLN A C     
1012 O O     . GLN C 45 ? 0.7068 0.6685 0.6587 0.0466  0.0652  0.0268  275 GLN A O     
1013 C CB    . GLN C 45 ? 0.6447 0.6258 0.6213 0.0443  0.0594  0.0334  275 GLN A CB    
1014 C CG    . GLN C 45 ? 0.7157 0.7129 0.7192 0.0483  0.0558  0.0369  275 GLN A CG    
1015 C CD    . GLN C 45 ? 0.6894 0.7028 0.7142 0.0416  0.0574  0.0346  275 GLN A CD    
1016 O OE1   . GLN C 45 ? 0.6832 0.6957 0.6996 0.0319  0.0526  0.0324  275 GLN A OE1   
1017 N NE2   . GLN C 45 ? 0.7783 0.8029 0.8307 0.0446  0.0691  0.0327  275 GLN A NE2   
1018 N N     . VAL C 46 ? 0.6840 0.6421 0.6326 0.0416  0.0618  0.0280  276 VAL A N     
1019 C CA    . VAL C 46 ? 0.6674 0.6218 0.6191 0.0433  0.0643  0.0260  276 VAL A CA    
1020 C C     . VAL C 46 ? 0.6674 0.6221 0.6234 0.0439  0.0671  0.0218  276 VAL A C     
1021 O O     . VAL C 46 ? 0.6984 0.6598 0.6653 0.0462  0.0646  0.0204  276 VAL A O     
1022 C CB    . VAL C 46 ? 0.6241 0.5693 0.5772 0.0411  0.0682  0.0241  276 VAL A CB    
1023 C CG1   . VAL C 46 ? 0.6269 0.5717 0.5955 0.0479  0.0690  0.0250  276 VAL A CG1   
1024 C CG2   . VAL C 46 ? 0.6559 0.5984 0.6064 0.0373  0.0680  0.0268  276 VAL A CG2   
1025 N N     . LYS C 47 ? 0.7295 0.6766 0.6760 0.0402  0.0715  0.0204  277 LYS A N     
1026 C CA    . LYS C 47 ? 0.6997 0.6433 0.6504 0.0376  0.0794  0.0157  277 LYS A CA    
1027 C C     . LYS C 47 ? 0.6893 0.6379 0.6458 0.0390  0.0769  0.0150  277 LYS A C     
1028 O O     . LYS C 47 ? 0.6706 0.6262 0.6413 0.0361  0.0786  0.0085  277 LYS A O     
1029 C CB    . LYS C 47 ? 0.7129 0.6384 0.6402 0.0314  0.0864  0.0171  277 LYS A CB    
1030 C CG    . LYS C 47 ? 0.7613 0.6768 0.6893 0.0250  0.1014  0.0114  277 LYS A CG    
1031 C CD    . LYS C 47 ? 0.8850 0.7744 0.7796 0.0189  0.1078  0.0179  277 LYS A CD    
1032 C CE    . LYS C 47 ? 1.0547 0.9293 0.9123 0.0148  0.1012  0.0249  277 LYS A CE    
1033 N NZ    . LYS C 47 ? 1.1814 1.0568 1.0311 0.0224  0.0822  0.0394  277 LYS A NZ    
1034 N N     . THR C 48 ? 0.6969 0.6420 0.6457 0.0422  0.0742  0.0198  278 THR A N     
1035 C CA    . THR C 48 ? 0.6606 0.6029 0.6117 0.0420  0.0777  0.0160  278 THR A CA    
1036 C C     . THR C 48 ? 0.7582 0.7116 0.7106 0.0396  0.0725  0.0105  278 THR A C     
1037 O O     . THR C 48 ? 0.7235 0.6768 0.6756 0.0334  0.0737  0.0021  278 THR A O     
1038 C CB    . THR C 48 ? 0.7637 0.7003 0.7154 0.0483  0.0792  0.0218  278 THR A CB    
1039 O OG1   . THR C 48 ? 0.6190 0.5464 0.5644 0.0506  0.0766  0.0308  278 THR A OG1   
1040 C CG2   . THR C 48 ? 0.7963 0.7217 0.7505 0.0479  0.0896  0.0153  278 THR A CG2   
1041 N N     . TRP C 49 ? 0.6296 0.5897 0.5794 0.0424  0.0663  0.0155  279 TRP A N     
1042 C CA    . TRP C 49 ? 0.6519 0.6173 0.5939 0.0403  0.0585  0.0152  279 TRP A CA    
1043 C C     . TRP C 49 ? 0.6662 0.6430 0.6225 0.0384  0.0492  0.0121  279 TRP A C     
1044 O O     . TRP C 49 ? 0.7422 0.7245 0.6942 0.0320  0.0423  0.0062  279 TRP A O     
1045 C CB    . TRP C 49 ? 0.8216 0.7851 0.7571 0.0434  0.0558  0.0239  279 TRP A CB    
1046 C CG    . TRP C 49 ? 0.7667 0.7280 0.6830 0.0410  0.0468  0.0280  279 TRP A CG    
1047 C CD1   . TRP C 49 ? 0.8544 0.8060 0.7425 0.0345  0.0519  0.0265  279 TRP A CD1   
1048 C CD2   . TRP C 49 ? 0.7495 0.7160 0.6697 0.0444  0.0307  0.0352  279 TRP A CD2   
1049 N NE1   . TRP C 49 ? 0.7660 0.7131 0.6294 0.0315  0.0383  0.0335  279 TRP A NE1   
1050 C CE2   . TRP C 49 ? 0.8097 0.7678 0.6958 0.0392  0.0223  0.0406  279 TRP A CE2   
1051 C CE3   . TRP C 49 ? 0.7959 0.7725 0.7469 0.0518  0.0237  0.0380  279 TRP A CE3   
1052 C CZ2   . TRP C 49 ? 0.8717 0.8322 0.7518 0.0425  0.0010  0.0523  279 TRP A CZ2   
1053 C CZ3   . TRP C 49 ? 0.7490 0.7312 0.7064 0.0574  0.0055  0.0480  279 TRP A CZ3   
1054 C CH2   . TRP C 49 ? 0.8451 0.8205 0.7670 0.0534  -0.0090 0.0567  279 TRP A CH2   
1055 N N     . TYR C 50 ? 0.7227 0.7043 0.6993 0.0429  0.0495  0.0144  280 TYR A N     
1056 C CA    . TYR C 50 ? 0.6602 0.6578 0.6664 0.0431  0.0439  0.0107  280 TYR A CA    
1057 C C     . TYR C 50 ? 0.6335 0.6373 0.6495 0.0332  0.0482  -0.0008 280 TYR A C     
1058 O O     . TYR C 50 ? 0.7483 0.7713 0.7842 0.0287  0.0366  -0.0060 280 TYR A O     
1059 C CB    . TYR C 50 ? 0.6620 0.6574 0.6894 0.0479  0.0547  0.0106  280 TYR A CB    
1060 C CG    . TYR C 50 ? 0.6242 0.6259 0.6744 0.0581  0.0466  0.0178  280 TYR A CG    
1061 C CD1   . TYR C 50 ? 0.6312 0.6172 0.6657 0.0635  0.0466  0.0267  280 TYR A CD1   
1062 C CD2   . TYR C 50 ? 0.6321 0.6550 0.7265 0.0626  0.0405  0.0157  280 TYR A CD2   
1063 C CE1   . TYR C 50 ? 0.6548 0.6394 0.7110 0.0743  0.0412  0.0352  280 TYR A CE1   
1064 C CE2   . TYR C 50 ? 0.6807 0.7082 0.8043 0.0758  0.0326  0.0248  280 TYR A CE2   
1065 C CZ    . TYR C 50 ? 0.6386 0.6433 0.7404 0.0824  0.0334  0.0356  280 TYR A CZ    
1066 O OH    . TYR C 50 ? 0.6926 0.6966 0.8265 0.0972  0.0270  0.0463  280 TYR A OH    
1067 N N     . GLN C 51 ? 0.6488 0.6357 0.6511 0.0289  0.0633  -0.0044 281 GLN A N     
1068 C CA    . GLN C 51 ? 0.6273 0.6123 0.6378 0.0181  0.0719  -0.0151 281 GLN A CA    
1069 C C     . GLN C 51 ? 0.7155 0.7016 0.7130 0.0101  0.0642  -0.0226 281 GLN A C     
1070 O O     . GLN C 51 ? 0.7065 0.7029 0.7185 -0.0018 0.0619  -0.0344 281 GLN A O     
1071 C CB    . GLN C 51 ? 0.7028 0.6609 0.6943 0.0184  0.0887  -0.0113 281 GLN A CB    
1072 C CG    . GLN C 51 ? 0.7102 0.6540 0.7042 0.0072  0.1033  -0.0197 281 GLN A CG    
1073 C CD    . GLN C 51 ? 0.7563 0.7153 0.7815 -0.0021 0.1106  -0.0294 281 GLN A CD    
1074 O OE1   . GLN C 51 ? 0.7373 0.7037 0.7751 0.0016  0.1146  -0.0272 281 GLN A OE1   
1075 N NE2   . GLN C 51 ? 0.7079 0.6738 0.7509 -0.0156 0.1137  -0.0426 281 GLN A NE2   
1076 N N     . ASN C 52 ? 0.8334 0.8065 0.8028 0.0141  0.0637  -0.0181 282 ASN A N     
1077 C CA    . ASN C 52 ? 0.7593 0.7269 0.7063 0.0049  0.0610  -0.0269 282 ASN A CA    
1078 C C     . ASN C 52 ? 0.8652 0.8545 0.8101 0.0000  0.0372  -0.0268 282 ASN A C     
1079 O O     . ASN C 52 ? 0.9490 0.9399 0.8777 -0.0142 0.0294  -0.0382 282 ASN A O     
1080 C CB    . ASN C 52 ? 0.7857 0.7364 0.7089 0.0108  0.0701  -0.0223 282 ASN A CB    
1081 C CG    . ASN C 52 ? 0.7692 0.6988 0.6969 0.0147  0.0901  -0.0239 282 ASN A CG    
1082 O OD1   . ASN C 52 ? 0.6654 0.5825 0.5966 0.0070  0.0997  -0.0337 282 ASN A OD1   
1083 N ND2   . ASN C 52 ? 0.7272 0.6517 0.6577 0.0261  0.0962  -0.0144 282 ASN A ND2   
1084 N N     . ARG C 53 ? 0.7587 0.7622 0.7187 0.0114  0.0248  -0.0136 283 ARG A N     
1085 C CA    . ARG C 53 ? 0.7826 0.8033 0.7407 0.0113  -0.0011 -0.0069 283 ARG A CA    
1086 C C     . ARG C 53 ? 0.7805 0.8300 0.7774 0.0037  -0.0150 -0.0162 283 ARG A C     
1087 O O     . ARG C 53 ? 0.7932 0.8578 0.7817 -0.0058 -0.0390 -0.0188 283 ARG A O     
1088 C CB    . ARG C 53 ? 0.8930 0.9148 0.8596 0.0271  -0.0082 0.0108  283 ARG A CB    
1089 C CG    . ARG C 53 ? 1.0040 1.0364 0.9633 0.0301  -0.0373 0.0238  283 ARG A CG    
1090 C CD    . ARG C 53 ? 1.0159 1.0304 0.9129 0.0190  -0.0465 0.0263  283 ARG A CD    
1091 N NE    . ARG C 53 ? 1.0548 1.0777 0.9367 0.0200  -0.0804 0.0415  283 ARG A NE    
1092 C CZ    . ARG C 53 ? 1.0583 1.1088 0.9544 0.0131  -0.1109 0.0391  283 ARG A CZ    
1093 N NH1   . ARG C 53 ? 1.0564 1.1136 0.9417 0.0188  -0.1453 0.0594  283 ARG A NH1   
1094 N NH2   . ARG C 53 ? 1.0272 1.0986 0.9506 0.0003  -0.1086 0.0180  283 ARG A NH2   
1095 N N     . ARG C 54 ? 0.7685 0.8248 0.8056 0.0055  0.0009  -0.0220 284 ARG A N     
1096 C CA    . ARG C 54 ? 0.8170 0.9031 0.9029 -0.0033 -0.0051 -0.0335 284 ARG A CA    
1097 C C     . ARG C 54 ? 0.7863 0.8706 0.8558 -0.0254 -0.0063 -0.0514 284 ARG A C     
1098 O O     . ARG C 54 ? 0.8596 0.9742 0.9525 -0.0371 -0.0288 -0.0597 284 ARG A O     
1099 C CB    . ARG C 54 ? 0.7594 0.8448 0.8835 0.0005  0.0205  -0.0369 284 ARG A CB    
1100 C CG    . ARG C 54 ? 0.6873 0.7815 0.8401 0.0185  0.0194  -0.0249 284 ARG A CG    
1101 C CD    . ARG C 54 ? 0.7005 0.7918 0.8865 0.0185  0.0484  -0.0320 284 ARG A CD    
1102 N NE    . ARG C 54 ? 0.7008 0.7547 0.8447 0.0143  0.0743  -0.0327 284 ARG A NE    
1103 C CZ    . ARG C 54 ? 0.6456 0.6785 0.7687 0.0229  0.0855  -0.0251 284 ARG A CZ    
1104 N NH1   . ARG C 54 ? 0.6379 0.6794 0.7789 0.0357  0.0773  -0.0181 284 ARG A NH1   
1105 N NH2   . ARG C 54 ? 0.6278 0.6302 0.7125 0.0184  0.1027  -0.0238 284 ARG A NH2   
1106 N N     . THR C 55 ? 0.7980 0.8471 0.8299 -0.0313 0.0164  -0.0578 285 THR A N     
1107 C CA    . THR C 55 ? 0.8480 0.8859 0.8624 -0.0529 0.0220  -0.0773 285 THR A CA    
1108 C C     . THR C 55 ? 0.8872 0.9371 0.8711 -0.0647 -0.0066 -0.0817 285 THR A C     
1109 O O     . THR C 55 ? 0.8564 0.9216 0.8474 -0.0861 -0.0186 -0.0991 285 THR A O     
1110 C CB    . THR C 55 ? 0.8921 0.8861 0.8723 -0.0516 0.0509  -0.0796 285 THR A CB    
1111 O OG1   . THR C 55 ? 0.8990 0.8837 0.8904 -0.0334 0.0644  -0.0641 285 THR A OG1   
1112 C CG2   . THR C 55 ? 0.9880 0.9630 0.9725 -0.0705 0.0708  -0.0989 285 THR A CG2   
1113 N N     . LYS C 56 ? 0.9196 0.9607 0.8667 -0.0531 -0.0173 -0.0662 286 LYS A N     
1114 C CA    . LYS C 56 ? 1.1009 1.1465 1.0048 -0.0640 -0.0454 -0.0654 286 LYS A CA    
1115 C C     . LYS C 56 ? 1.0837 1.1750 1.0269 -0.0639 -0.0851 -0.0585 286 LYS A C     
1116 O O     . LYS C 56 ? 1.0816 1.1888 1.0087 -0.0838 -0.1121 -0.0685 286 LYS A O     
1117 C CB    . LYS C 56 ? 1.1016 1.1227 0.9576 -0.0520 -0.0425 -0.0482 286 LYS A CB    
1118 C CG    . LYS C 56 ? 1.1660 1.1817 0.9617 -0.0642 -0.0688 -0.0438 286 LYS A CG    
1119 C CD    . LYS C 56 ? 1.1796 1.1632 0.9244 -0.0563 -0.0557 -0.0294 286 LYS A CD    
1120 C CE    . LYS C 56 ? 1.2153 1.1964 0.9092 -0.0612 -0.0881 -0.0129 286 LYS A CE    
1121 N NZ    . LYS C 56 ? 1.2219 1.1696 0.8699 -0.0548 -0.0713 0.0019  286 LYS A NZ    
1122 N N     . TRP C 57 ? 0.9042 1.0160 0.9004 -0.0420 -0.0883 -0.0422 287 TRP A N     
1123 C CA    . TRP C 57 ? 1.0095 1.1675 1.0637 -0.0357 -0.1214 -0.0341 287 TRP A CA    
1124 C C     . TRP C 57 ? 0.9933 1.1860 1.0925 -0.0574 -0.1306 -0.0566 287 TRP A C     
1125 O O     . TRP C 57 ? 1.0155 1.2417 1.1240 -0.0680 -0.1705 -0.0573 287 TRP A O     
1126 C CB    . TRP C 57 ? 1.0329 1.1983 1.1429 -0.0108 -0.1063 -0.0210 287 TRP A CB    
1127 C CG    . TRP C 57 ? 0.9597 1.1733 1.1507 -0.0009 -0.1294 -0.0157 287 TRP A CG    
1128 C CD1   . TRP C 57 ? 0.9868 1.2330 1.1963 0.0036  -0.1746 -0.0022 287 TRP A CD1   
1129 C CD2   . TRP C 57 ? 1.0198 1.2537 1.2879 0.0067  -0.1062 -0.0231 287 TRP A CD2   
1130 N NE1   . TRP C 57 ? 1.0256 1.3160 1.3306 0.0162  -0.1820 -0.0006 287 TRP A NE1   
1131 C CE2   . TRP C 57 ? 1.0943 1.3772 1.4365 0.0172  -0.1372 -0.0152 287 TRP A CE2   
1132 C CE3   . TRP C 57 ? 1.0222 1.2361 1.3016 0.0051  -0.0624 -0.0347 287 TRP A CE3   
1133 C CZ2   . TRP C 57 ? 1.0428 1.3560 1.4764 0.0258  -0.1195 -0.0223 287 TRP A CZ2   
1134 C CZ3   . TRP C 57 ? 0.9622 1.2006 1.3179 0.0107  -0.0450 -0.0412 287 TRP A CZ3   
1135 C CH2   . TRP C 57 ? 0.9940 1.2821 1.4293 0.0208  -0.0705 -0.0368 287 TRP A CH2   
1136 N N     . LYS C 58 ? 1.0300 1.2135 1.1553 -0.0653 -0.0947 -0.0741 288 LYS A N     
1137 C CA    . LYS C 58 ? 1.0016 1.2128 1.1731 -0.0889 -0.0944 -0.0979 288 LYS A CA    
1138 C C     . LYS C 58 ? 0.9564 1.1637 1.0780 -0.1176 -0.1149 -0.1150 288 LYS A C     
1139 O O     . LYS C 58 ? 0.9268 1.1739 1.0855 -0.1381 -0.1394 -0.1301 288 LYS A O     
1140 C CB    . LYS C 58 ? 1.0030 1.1890 1.1915 -0.0955 -0.0473 -0.1121 288 LYS A CB    
1141 C CG    . LYS C 58 ? 1.0713 1.2584 1.3048 -0.0748 -0.0223 -0.1010 288 LYS A CG    
1142 C CD    . LYS C 58 ? 1.1668 1.3269 1.4099 -0.0855 0.0214  -0.1136 288 LYS A CD    
1143 C CE    . LYS C 58 ? 1.2434 1.3939 1.5097 -0.0689 0.0490  -0.1035 288 LYS A CE    
1144 N NZ    . LYS C 58 ? 1.3314 1.4378 1.5389 -0.0521 0.0623  -0.0871 288 LYS A NZ    
1145 N N     . ARG C 59 ? 1.0824 1.2419 1.1221 -0.1204 -0.1029 -0.1145 289 ARG A N     
1146 C CA    . ARG C 59 ? 1.2382 1.3817 1.2131 -0.1483 -0.1160 -0.1319 289 ARG A CA    
1147 C C     . ARG C 59 ? 1.2683 1.4472 1.2288 -0.1529 -0.1716 -0.1206 289 ARG A C     
1148 O O     . ARG C 59 ? 1.3264 1.5245 1.2751 -0.1820 -0.1984 -0.1390 289 ARG A O     
1149 C CB    . ARG C 59 ? 1.3117 1.3956 1.2104 -0.1455 -0.0843 -0.1320 289 ARG A CB    
1150 C CG    . ARG C 59 ? 1.4237 1.4769 1.2475 -0.1756 -0.0829 -0.1547 289 ARG A CG    
1151 C CD    . ARG C 59 ? 1.5478 1.5878 1.3817 -0.2048 -0.0606 -0.1887 289 ARG A CD    
1152 N NE    . ARG C 59 ? 1.5943 1.6760 1.4533 -0.2343 -0.0947 -0.2076 289 ARG A NE    
1153 C CZ    . ARG C 59 ? 1.6313 1.7267 1.4423 -0.2603 -0.1336 -0.2177 289 ARG A CZ    
1154 N NH1   . ARG C 59 ? 1.7050 1.7734 1.4330 -0.2599 -0.1441 -0.2078 289 ARG A NH1   
1155 N NH2   . ARG C 59 ? 1.6413 1.7778 1.4857 -0.2891 -0.1631 -0.2379 289 ARG A NH2   
1156 N N     . GLN C 60 ? 1.2544 1.4410 1.2164 -0.1252 -0.1907 -0.0896 290 GLN A N     
1157 C CA    . GLN C 60 ? 1.3449 1.5622 1.2962 -0.1243 -0.2463 -0.0715 290 GLN A CA    
1158 C C     . GLN C 60 ? 1.4505 1.7369 1.5005 -0.1233 -0.2817 -0.0719 290 GLN A C     
1159 O O     . GLN C 60 ? 1.6449 1.9655 1.6933 -0.1299 -0.3353 -0.0624 290 GLN A O     
1160 C CB    . GLN C 60 ? 1.3504 1.5469 1.2730 -0.0948 -0.2520 -0.0369 290 GLN A CB    
1161 C CG    . GLN C 60 ? 1.4150 1.5598 1.2245 -0.1065 -0.2485 -0.0329 290 GLN A CG    
1162 C CD    . GLN C 60 ? 1.4031 1.5068 1.1873 -0.0833 -0.2148 -0.0147 290 GLN A CD    
1163 O OE1   . GLN C 60 ? 1.4136 1.5279 1.2550 -0.0558 -0.2070 0.0024  290 GLN A OE1   
1164 N NE2   . GLN C 60 ? 1.4439 1.4997 1.1435 -0.0966 -0.1916 -0.0213 290 GLN A NE2   
1165 N N     . THR C 61 ? 1.5127 1.8203 1.6493 -0.1153 -0.2527 -0.0818 291 THR A N     
1166 C CA    . THR C 61 ? 1.5020 1.8770 1.7422 -0.1191 -0.2773 -0.0890 291 THR A CA    
1167 C C     . THR C 61 ? 1.5995 1.9907 1.8387 -0.1610 -0.2832 -0.1239 291 THR A C     
1168 O O     . THR C 61 ? 1.5742 2.0267 1.8778 -0.1745 -0.3226 -0.1315 291 THR A O     
1169 C CB    . THR C 61 ? 1.3663 1.7511 1.6919 -0.0974 -0.2374 -0.0878 291 THR A CB    
1170 O OG1   . THR C 61 ? 1.2364 1.6048 1.5532 -0.0627 -0.2390 -0.0569 291 THR A OG1   
1171 C CG2   . THR C 61 ? 1.2665 1.7214 1.7111 -0.1017 -0.2521 -0.0986 291 THR A CG2   
1172 N N     . ALA C 62 ? 1.7087 2.0448 1.8788 -0.1816 -0.2441 -0.1453 292 ALA A N     
1173 C CA    . ALA C 62 ? 1.8277 2.1631 1.9798 -0.2240 -0.2435 -0.1807 292 ALA A CA    
1174 C C     . ALA C 62 ? 2.1056 2.4258 2.1609 -0.2475 -0.2810 -0.1850 292 ALA A C     
1175 O O     . ALA C 62 ? 2.0190 2.3423 2.0534 -0.2869 -0.2897 -0.2159 292 ALA A O     
1176 C CB    . ALA C 62 ? 1.7790 2.0571 1.9084 -0.2326 -0.1803 -0.2004 292 ALA A CB    
1177 N N     . VAL C 63 ? 2.3645 2.6639 2.3565 -0.2263 -0.3004 -0.1555 293 VAL A N     
1178 C CA    . VAL C 63 ? 2.4163 2.6927 2.3022 -0.2479 -0.3330 -0.1556 293 VAL A CA    
1179 C C     . VAL C 63 ? 2.5366 2.8773 2.4492 -0.2550 -0.4083 -0.1428 293 VAL A C     
1180 O O     . VAL C 63 ? 2.5812 2.9089 2.4039 -0.2730 -0.4471 -0.1374 293 VAL A O     
1181 C CB    . VAL C 63 ? 2.2292 2.4471 2.0275 -0.2267 -0.3143 -0.1312 293 VAL A CB    
1182 C CG1   . VAL C 63 ? 2.0821 2.3213 1.8913 -0.1942 -0.3542 -0.0881 293 VAL A CG1   
1183 C CG2   . VAL C 63 ? 2.2720 2.4371 1.9456 -0.2593 -0.3097 -0.1489 293 VAL A CG2   
1188 N N     . LYS D 1  ? 1.3501 1.1926 1.7388 -0.2540 -0.1628 -0.0752 230 LYS E N     
1189 C CA    . LYS D 1  ? 1.3849 1.2992 1.8671 -0.2675 -0.1417 -0.0558 230 LYS E CA    
1190 C C     . LYS D 1  ? 1.2999 1.2536 1.7654 -0.2397 -0.1161 -0.0557 230 LYS E C     
1191 O O     . LYS D 1  ? 1.2348 1.2240 1.7414 -0.2332 -0.1341 -0.0591 230 LYS E O     
1192 C CB    . LYS D 1  ? 1.4443 1.3671 1.9670 -0.2926 -0.1072 -0.0320 230 LYS E CB    
1193 C CG    . LYS D 1  ? 1.4324 1.4248 2.0641 -0.3147 -0.0870 -0.0122 230 LYS E CG    
1194 C CD    . LYS D 1  ? 1.4766 1.4875 2.1968 -0.3383 -0.1327 -0.0154 230 LYS E CD    
1195 C CE    . LYS D 1  ? 1.4574 1.5520 2.2946 -0.3507 -0.1107 0.0014  230 LYS E CE    
1196 N NZ    . LYS D 1  ? 1.4463 1.5851 2.2808 -0.3190 -0.0891 -0.0041 230 LYS E NZ    
1197 N N     . LYS D 2  ? 1.2189 1.1630 1.6257 -0.2233 -0.0784 -0.0515 231 LYS E N     
1198 C CA    . LYS D 2  ? 1.2926 1.2580 1.6688 -0.1964 -0.0598 -0.0548 231 LYS E CA    
1199 C C     . LYS D 2  ? 1.1926 1.1143 1.4881 -0.1755 -0.0851 -0.0718 231 LYS E C     
1200 O O     . LYS D 2  ? 1.1447 1.0225 1.3794 -0.1703 -0.0822 -0.0769 231 LYS E O     
1201 C CB    . LYS D 2  ? 1.3502 1.3301 1.7073 -0.1909 -0.0101 -0.0426 231 LYS E CB    
1202 C CG    . LYS D 2  ? 1.4483 1.3984 1.7786 -0.2054 0.0086  -0.0302 231 LYS E CG    
1203 C CD    . LYS D 2  ? 1.4396 1.3317 1.6944 -0.1943 -0.0051 -0.0381 231 LYS E CD    
1204 C CE    . LYS D 2  ? 1.4894 1.3396 1.7441 -0.2137 -0.0152 -0.0307 231 LYS E CE    
1205 N NZ    . LYS D 2  ? 1.4669 1.2936 1.7504 -0.2284 -0.0547 -0.0417 231 LYS E NZ    
1206 N N     . PRO D 3  ? 1.0703 1.0007 1.3626 -0.1628 -0.1115 -0.0802 232 PRO E N     
1207 C CA    . PRO D 3  ? 1.1105 1.0008 1.3190 -0.1436 -0.1287 -0.0936 232 PRO E CA    
1208 C C     . PRO D 3  ? 1.0397 0.9239 1.1965 -0.1262 -0.0906 -0.0895 232 PRO E C     
1209 O O     . PRO D 3  ? 1.0456 0.9626 1.2286 -0.1237 -0.0599 -0.0785 232 PRO E O     
1210 C CB    . PRO D 3  ? 1.1010 1.0110 1.3231 -0.1345 -0.1575 -0.0950 232 PRO E CB    
1211 C CG    . PRO D 3  ? 1.1633 1.1145 1.4860 -0.1538 -0.1725 -0.0879 232 PRO E CG    
1212 C CD    . PRO D 3  ? 1.1271 1.1040 1.4952 -0.1660 -0.1277 -0.0759 232 PRO E CD    
1213 N N     . ARG D 4  ? 0.9450 0.7862 1.0307 -0.1149 -0.0936 -0.1000 233 ARG E N     
1214 C CA    . ARG D 4  ? 0.8654 0.7004 0.9037 -0.0974 -0.0646 -0.0970 233 ARG E CA    
1215 C C     . ARG D 4  ? 0.8422 0.7021 0.8743 -0.0836 -0.0596 -0.0918 233 ARG E C     
1216 O O     . ARG D 4  ? 0.9343 0.7965 0.9666 -0.0813 -0.0855 -0.0948 233 ARG E O     
1217 C CB    . ARG D 4  ? 0.9268 0.7133 0.9018 -0.0873 -0.0738 -0.1121 233 ARG E CB    
1218 C CG    . ARG D 4  ? 0.9896 0.7716 0.9225 -0.0683 -0.0459 -0.1094 233 ARG E CG    
1219 C CD    . ARG D 4  ? 0.9908 0.7291 0.8829 -0.0590 -0.0458 -0.1228 233 ARG E CD    
1220 N NE    . ARG D 4  ? 0.9316 0.6798 0.8044 -0.0423 -0.0173 -0.1155 233 ARG E NE    
1221 C CZ    . ARG D 4  ? 0.8748 0.6177 0.7580 -0.0401 -0.0023 -0.1086 233 ARG E CZ    
1222 N NH1   . ARG D 4  ? 0.9557 0.6746 0.8568 -0.0510 -0.0110 -0.1089 233 ARG E NH1   
1223 N NH2   . ARG D 4  ? 0.8626 0.6231 0.7408 -0.0281 0.0190  -0.0993 233 ARG E NH2   
1224 N N     . LYS D 5  ? 0.7886 0.6655 0.8182 -0.0760 -0.0299 -0.0827 234 LYS E N     
1225 C CA    . LYS D 5  ? 0.7672 0.6617 0.7941 -0.0643 -0.0266 -0.0773 234 LYS E CA    
1226 C C     . LYS D 5  ? 0.8845 0.7529 0.8473 -0.0507 -0.0337 -0.0810 234 LYS E C     
1227 O O     . LYS D 5  ? 0.9892 0.8340 0.9139 -0.0463 -0.0260 -0.0871 234 LYS E O     
1228 C CB    . LYS D 5  ? 0.7162 0.6308 0.7539 -0.0601 0.0029  -0.0689 234 LYS E CB    
1229 C CG    . LYS D 5  ? 0.8365 0.7727 0.9175 -0.0717 0.0222  -0.0654 234 LYS E CG    
1230 C CD    . LYS D 5  ? 0.9472 0.9060 1.0477 -0.0667 0.0432  -0.0623 234 LYS E CD    
1231 C CE    . LYS D 5  ? 0.9922 0.9573 1.0925 -0.0742 0.0706  -0.0596 234 LYS E CE    
1232 N NZ    . LYS D 5  ? 1.1180 1.0787 1.2268 -0.0896 0.0730  -0.0556 234 LYS E NZ    
1233 N N     . ALA D 6  ? 0.8748 0.7482 0.8282 -0.0431 -0.0456 -0.0755 235 ALA E N     
1234 C CA    . ALA D 6  ? 0.9063 0.7592 0.7969 -0.0311 -0.0458 -0.0737 235 ALA E CA    
1235 C C     . ALA D 6  ? 0.8784 0.7348 0.7546 -0.0248 -0.0127 -0.0685 235 ALA E C     
1236 O O     . ALA D 6  ? 0.8033 0.6796 0.7161 -0.0284 0.0036  -0.0628 235 ALA E O     
1237 C CB    . ALA D 6  ? 0.9138 0.7726 0.8036 -0.0262 -0.0627 -0.0621 235 ALA E CB    
1238 N N     . ARG D 7  ? 0.8839 0.7209 0.7072 -0.0154 -0.0036 -0.0716 236 ARG E N     
1239 C CA    . ARG D 7  ? 0.8188 0.6629 0.6360 -0.0088 0.0254  -0.0659 236 ARG E CA    
1240 C C     . ARG D 7  ? 0.8813 0.7398 0.6995 -0.0067 0.0339  -0.0489 236 ARG E C     
1241 O O     . ARG D 7  ? 1.0486 0.8966 0.8304 -0.0024 0.0266  -0.0429 236 ARG E O     
1242 C CB    . ARG D 7  ? 0.9360 0.7563 0.7036 0.0024  0.0334  -0.0773 236 ARG E CB    
1243 C CG    . ARG D 7  ? 0.9498 0.7797 0.7235 0.0111  0.0619  -0.0737 236 ARG E CG    
1244 C CD    . ARG D 7  ? 0.8859 0.7007 0.6098 0.0269  0.0783  -0.0810 236 ARG E CD    
1245 N NE    . ARG D 7  ? 0.7906 0.6300 0.5350 0.0342  0.1074  -0.0688 236 ARG E NE    
1246 C CZ    . ARG D 7  ? 0.8310 0.6754 0.6028 0.0415  0.1195  -0.0726 236 ARG E CZ    
1247 N NH1   . ARG D 7  ? 0.8929 0.7144 0.6698 0.0423  0.1065  -0.0875 236 ARG E NH1   
1248 N NH2   . ARG D 7  ? 0.8076 0.6798 0.6076 0.0466  0.1414  -0.0595 236 ARG E NH2   
1249 N N     . THR D 8  ? 0.9148 0.7930 0.7727 -0.0114 0.0454  -0.0410 237 THR E N     
1250 C CA    . THR D 8  ? 0.8636 0.7505 0.7301 -0.0117 0.0504  -0.0258 237 THR E CA    
1251 C C     . THR D 8  ? 0.8948 0.7778 0.7248 -0.0056 0.0659  -0.0156 237 THR E C     
1252 O O     . THR D 8  ? 0.9980 0.8845 0.8220 -0.0012 0.0824  -0.0200 237 THR E O     
1253 C CB    . THR D 8  ? 0.8413 0.7434 0.7466 -0.0177 0.0617  -0.0238 237 THR E CB    
1254 O OG1   . THR D 8  ? 0.7555 0.6634 0.6925 -0.0226 0.0536  -0.0317 237 THR E OG1   
1255 C CG2   . THR D 8  ? 0.8313 0.7363 0.7438 -0.0190 0.0671  -0.0091 237 THR E CG2   
1256 N N     . ALA D 9  ? 0.9317 0.8081 0.7409 -0.0048 0.0616  -0.0006 238 ALA E N     
1257 C CA    . ALA D 9  ? 0.9197 0.7978 0.7022 -0.0023 0.0824  0.0151  238 ALA E CA    
1258 C C     . ALA D 9  ? 0.8606 0.7499 0.6824 -0.0108 0.0878  0.0325  238 ALA E C     
1259 O O     . ALA D 9  ? 0.9107 0.7899 0.7389 -0.0141 0.0725  0.0434  238 ALA E O     
1260 C CB    . ALA D 9  ? 0.9845 0.8417 0.7044 0.0024  0.0756  0.0227  238 ALA E CB    
1261 N N     . PHE D 10 ? 0.8128 0.7207 0.6651 -0.0141 0.1055  0.0334  239 PHE E N     
1262 C CA    . PHE D 10 ? 0.8095 0.7256 0.6998 -0.0244 0.1084  0.0472  239 PHE E CA    
1263 C C     . PHE D 10 ? 0.9301 0.8445 0.8035 -0.0280 0.1208  0.0730  239 PHE E C     
1264 O O     . PHE D 10 ? 0.9043 0.8221 0.7416 -0.0217 0.1384  0.0783  239 PHE E O     
1265 C CB    . PHE D 10 ? 0.7565 0.6928 0.6803 -0.0274 0.1183  0.0407  239 PHE E CB    
1266 C CG    . PHE D 10 ? 0.8400 0.7748 0.7788 -0.0279 0.1064  0.0211  239 PHE E CG    
1267 C CD1   . PHE D 10 ? 0.8647 0.7921 0.8238 -0.0350 0.0941  0.0156  239 PHE E CD1   
1268 C CD2   . PHE D 10 ? 0.8208 0.7584 0.7509 -0.0209 0.1094  0.0084  239 PHE E CD2   
1269 C CE1   . PHE D 10 ? 0.7745 0.7015 0.7406 -0.0362 0.0887  -0.0003 239 PHE E CE1   
1270 C CE2   . PHE D 10 ? 0.7691 0.7039 0.7101 -0.0241 0.1004  -0.0043 239 PHE E CE2   
1271 C CZ    . PHE D 10 ? 0.7175 0.6488 0.6739 -0.0321 0.0919  -0.0080 239 PHE E CZ    
1272 N N     . SER D 11 ? 0.8504 0.7568 0.7478 -0.0384 0.1134  0.0891  240 SER E N     
1273 C CA    . SER D 11 ? 0.8664 0.7712 0.7558 -0.0462 0.1265  0.1184  240 SER E CA    
1274 C C     . SER D 11 ? 0.9281 0.8624 0.8577 -0.0548 0.1483  0.1260  240 SER E C     
1275 O O     . SER D 11 ? 0.8946 0.8425 0.8612 -0.0567 0.1434  0.1101  240 SER E O     
1276 C CB    . SER D 11 ? 0.8332 0.7126 0.7370 -0.0543 0.1071  0.1339  240 SER E CB    
1277 O OG    . SER D 11 ? 0.8647 0.7470 0.8225 -0.0660 0.1029  0.1315  240 SER E OG    
1278 N N     . ASP D 12 ? 1.0305 0.9760 0.9511 -0.0599 0.1725  0.1517  241 ASP E N     
1279 C CA    . ASP D 12 ? 1.0005 0.9780 0.9724 -0.0713 0.1932  0.1671  241 ASP E CA    
1280 C C     . ASP D 12 ? 0.9131 0.8890 0.9457 -0.0872 0.1711  0.1646  241 ASP E C     
1281 O O     . ASP D 12 ? 0.8589 0.8624 0.9376 -0.0914 0.1738  0.1588  241 ASP E O     
1282 C CB    . ASP D 12 ? 1.0458 1.0278 1.0015 -0.0799 0.2192  0.2021  241 ASP E CB    
1283 C CG    . ASP D 12 ? 1.1437 1.1389 1.0454 -0.0640 0.2523  0.2015  241 ASP E CG    
1284 O OD1   . ASP D 12 ? 1.0722 1.0793 0.9695 -0.0476 0.2561  0.1741  241 ASP E OD1   
1285 O OD2   . ASP D 12 ? 1.2922 1.2814 1.1518 -0.0677 0.2737  0.2279  241 ASP E OD2   
1286 N N     . HIS D 13 ? 0.8943 0.8356 0.9253 -0.0946 0.1478  0.1682  242 HIS E N     
1287 C CA    . HIS D 13 ? 0.9226 0.8518 1.0014 -0.1093 0.1264  0.1634  242 HIS E CA    
1288 C C     . HIS D 13 ? 0.9196 0.8502 1.0037 -0.1014 0.1109  0.1289  242 HIS E C     
1289 O O     . HIS D 13 ? 0.8658 0.8070 0.9858 -0.1111 0.1024  0.1206  242 HIS E O     
1290 C CB    . HIS D 13 ? 1.0214 0.9074 1.0931 -0.1139 0.1069  0.1727  242 HIS E CB    
1291 C CG    . HIS D 13 ? 1.0836 0.9475 1.1967 -0.1262 0.0841  0.1611  242 HIS E CG    
1292 N ND1   . HIS D 13 ? 1.0503 0.9293 1.2104 -0.1447 0.0824  0.1648  242 HIS E ND1   
1293 C CD2   . HIS D 13 ? 1.1184 0.9456 1.2330 -0.1218 0.0618  0.1436  242 HIS E CD2   
1294 C CE1   . HIS D 13 ? 1.0563 0.9031 1.2361 -0.1523 0.0577  0.1481  242 HIS E CE1   
1295 N NE2   . HIS D 13 ? 1.1503 0.9656 1.3025 -0.1371 0.0478  0.1342  242 HIS E NE2   
1296 N N     . GLN D 14 ? 0.8331 0.7531 0.8799 -0.0851 0.1061  0.1103  243 GLN E N     
1297 C CA    . GLN D 14 ? 0.7924 0.7131 0.8411 -0.0794 0.0952  0.0817  243 GLN E CA    
1298 C C     . GLN D 14 ? 0.7958 0.7480 0.8600 -0.0795 0.1052  0.0786  243 GLN E C     
1299 O O     . GLN D 14 ? 0.7274 0.6821 0.8110 -0.0856 0.0930  0.0661  243 GLN E O     
1300 C CB    . GLN D 14 ? 0.7571 0.6657 0.7729 -0.0644 0.0899  0.0657  243 GLN E CB    
1301 C CG    . GLN D 14 ? 0.7605 0.6404 0.7745 -0.0623 0.0755  0.0682  243 GLN E CG    
1302 C CD    . GLN D 14 ? 0.8607 0.7368 0.8507 -0.0482 0.0692  0.0570  243 GLN E CD    
1303 O OE1   . GLN D 14 ? 0.8740 0.7605 0.8347 -0.0417 0.0760  0.0583  243 GLN E OE1   
1304 N NE2   . GLN D 14 ? 0.8878 0.7490 0.8937 -0.0431 0.0558  0.0444  243 GLN E NE2   
1305 N N     . LEU D 15 ? 0.7841 0.7584 0.8400 -0.0726 0.1266  0.0908  244 LEU E N     
1306 C CA    . LEU D 15 ? 0.7495 0.7538 0.8256 -0.0675 0.1367  0.0871  244 LEU E CA    
1307 C C     . LEU D 15 ? 0.7525 0.7781 0.8858 -0.0837 0.1322  0.0998  244 LEU E C     
1308 O O     . LEU D 15 ? 0.6651 0.7058 0.8253 -0.0849 0.1214  0.0919  244 LEU E O     
1309 C CB    . LEU D 15 ? 0.7806 0.8009 0.8351 -0.0540 0.1643  0.0949  244 LEU E CB    
1310 C CG    . LEU D 15 ? 0.8822 0.8825 0.8805 -0.0376 0.1649  0.0783  244 LEU E CG    
1311 C CD1   . LEU D 15 ? 0.9362 0.9435 0.9009 -0.0272 0.1933  0.0886  244 LEU E CD1   
1312 C CD2   . LEU D 15 ? 0.8162 0.8171 0.8165 -0.0283 0.1561  0.0562  244 LEU E CD2   
1313 N N     . ASN D 16 ? 0.8094 0.8344 0.9625 -0.0978 0.1373  0.1218  245 ASN E N     
1314 C CA    . ASN D 16 ? 0.8001 0.8482 1.0161 -0.1164 0.1326  0.1370  245 ASN E CA    
1315 C C     . ASN D 16 ? 0.7809 0.8083 1.0084 -0.1271 0.0981  0.1180  245 ASN E C     
1316 O O     . ASN D 16 ? 0.7133 0.7627 0.9779 -0.1327 0.0855  0.1153  245 ASN E O     
1317 C CB    . ASN D 16 ? 0.8158 0.8678 1.0501 -0.1306 0.1494  0.1681  245 ASN E CB    
1318 C CG    . ASN D 16 ? 0.9232 1.0088 1.1500 -0.1186 0.1888  0.1841  245 ASN E CG    
1319 O OD1   . ASN D 16 ? 1.1179 1.1897 1.2996 -0.1141 0.2074  0.1973  245 ASN E OD1   
1320 N ND2   . ASN D 16 ? 0.8770 1.0050 1.1442 -0.1112 0.2017  0.1822  245 ASN E ND2   
1321 N N     . GLN D 17 ? 0.7858 0.7712 0.9775 -0.1267 0.0836  0.1035  246 GLN E N     
1322 C CA    . GLN D 17 ? 0.8631 0.8214 1.0517 -0.1345 0.0556  0.0814  246 GLN E CA    
1323 C C     . GLN D 17 ? 0.7894 0.7554 0.9557 -0.1237 0.0496  0.0607  246 GLN E C     
1324 O O     . GLN D 17 ? 0.7503 0.7129 0.9253 -0.1333 0.0282  0.0506  246 GLN E O     
1325 C CB    . GLN D 17 ? 0.9668 0.8805 1.1256 -0.1317 0.0465  0.0673  246 GLN E CB    
1326 C CG    . GLN D 17 ? 1.0535 0.9428 1.2333 -0.1446 0.0421  0.0850  246 GLN E CG    
1327 C CD    . GLN D 17 ? 1.0767 0.9783 1.3090 -0.1685 0.0338  0.1036  246 GLN E CD    
1328 O OE1   . GLN D 17 ? 1.3428 1.2814 1.6043 -0.1738 0.0517  0.1296  246 GLN E OE1   
1329 N NE2   . GLN D 17 ? 0.9790 0.8499 1.2263 -0.1835 0.0071  0.0898  246 GLN E NE2   
1330 N N     . LEU D 18 ? 0.8174 0.7908 0.9527 -0.1054 0.0658  0.0557  247 LEU E N     
1331 C CA    . LEU D 18 ? 0.7043 0.6835 0.8223 -0.0969 0.0608  0.0414  247 LEU E CA    
1332 C C     . LEU D 18 ? 0.7718 0.7827 0.9313 -0.1012 0.0553  0.0528  247 LEU E C     
1333 O O     . LEU D 18 ? 0.7107 0.7183 0.8693 -0.1063 0.0343  0.0447  247 LEU E O     
1334 C CB    . LEU D 18 ? 0.7384 0.7180 0.8234 -0.0788 0.0767  0.0351  247 LEU E CB    
1335 C CG    . LEU D 18 ? 0.8135 0.7666 0.8647 -0.0737 0.0769  0.0218  247 LEU E CG    
1336 C CD1   . LEU D 18 ? 0.8125 0.7690 0.8399 -0.0590 0.0901  0.0205  247 LEU E CD1   
1337 C CD2   . LEU D 18 ? 0.8206 0.7555 0.8534 -0.0769 0.0649  0.0020  247 LEU E CD2   
1338 N N     . GLU D 19 ? 0.7572 0.7992 0.9542 -0.0996 0.0737  0.0730  248 GLU E N     
1339 C CA    . GLU D 19 ? 0.7094 0.7897 0.9590 -0.0996 0.0718  0.0846  248 GLU E CA    
1340 C C     . GLU D 19 ? 0.6619 0.7451 0.9534 -0.1223 0.0422  0.0895  248 GLU E C     
1341 O O     . GLU D 19 ? 0.6796 0.7835 1.0051 -0.1245 0.0236  0.0923  248 GLU E O     
1342 C CB    . GLU D 19 ? 0.7429 0.8621 1.0312 -0.0921 0.1035  0.1047  248 GLU E CB    
1343 C CG    . GLU D 19 ? 0.7767 0.8935 1.0229 -0.0689 0.1330  0.0989  248 GLU E CG    
1344 C CD    . GLU D 19 ? 0.7566 0.8793 0.9990 -0.0498 0.1317  0.0869  248 GLU E CD    
1345 O OE1   . GLU D 19 ? 0.8190 0.9383 1.0317 -0.0307 0.1543  0.0802  248 GLU E OE1   
1346 O OE2   . GLU D 19 ? 0.7495 0.8755 1.0153 -0.0548 0.1054  0.0843  248 GLU E OE2   
1347 N N     . ARG D 20 ? 0.7066 0.7669 0.9981 -0.1394 0.0347  0.0912  249 ARG E N     
1348 C CA    . ARG D 20 ? 0.7235 0.7780 1.0510 -0.1632 0.0024  0.0923  249 ARG E CA    
1349 C C     . ARG D 20 ? 0.8452 0.8670 1.1271 -0.1649 -0.0284 0.0670  249 ARG E C     
1350 O O     . ARG D 20 ? 0.8982 0.9269 1.2038 -0.1773 -0.0591 0.0666  249 ARG E O     
1351 C CB    . ARG D 20 ? 0.7193 0.7464 1.0551 -0.1812 -0.0007 0.0979  249 ARG E CB    
1352 C CG    . ARG D 20 ? 0.7381 0.8035 1.1469 -0.1957 0.0126  0.1298  249 ARG E CG    
1353 C CD    . ARG D 20 ? 0.7456 0.7808 1.1630 -0.2141 0.0120  0.1415  249 ARG E CD    
1354 N NE    . ARG D 20 ? 0.8010 0.8185 1.2612 -0.2429 -0.0236 0.1415  249 ARG E NE    
1355 C CZ    . ARG D 20 ? 0.7810 0.7626 1.2494 -0.2598 -0.0289 0.1500  249 ARG E CZ    
1356 N NH1   . ARG D 20 ? 0.8102 0.7725 1.2443 -0.2488 -0.0031 0.1596  249 ARG E NH1   
1357 N NH2   . ARG D 20 ? 0.8016 0.7625 1.3097 -0.2872 -0.0630 0.1487  249 ARG E NH2   
1358 N N     . SER D 21 ? 0.8567 0.8447 1.0734 -0.1530 -0.0201 0.0471  250 SER E N     
1359 C CA    . SER D 21 ? 0.9381 0.8969 1.1030 -0.1528 -0.0401 0.0242  250 SER E CA    
1360 C C     . SER D 21 ? 0.7945 0.7774 0.9669 -0.1482 -0.0531 0.0303  250 SER E C     
1361 O O     . SER D 21 ? 0.8278 0.8008 0.9917 -0.1596 -0.0852 0.0248  250 SER E O     
1362 C CB    . SER D 21 ? 0.9908 0.9239 1.0989 -0.1378 -0.0203 0.0070  250 SER E CB    
1363 O OG    . SER D 21 ? 1.0227 0.9265 1.0786 -0.1396 -0.0341 -0.0148 250 SER E OG    
1364 N N     . PHE D 22 ? 0.7799 0.7920 0.9680 -0.1308 -0.0299 0.0422  251 PHE E N     
1365 C CA    . PHE D 22 ? 0.7358 0.7642 0.9275 -0.1206 -0.0386 0.0473  251 PHE E CA    
1366 C C     . PHE D 22 ? 0.8051 0.8644 1.0614 -0.1311 -0.0655 0.0631  251 PHE E C     
1367 O O     . PHE D 22 ? 0.9007 0.9630 1.1567 -0.1296 -0.0910 0.0661  251 PHE E O     
1368 C CB    . PHE D 22 ? 0.6355 0.6823 0.8323 -0.0987 -0.0055 0.0532  251 PHE E CB    
1369 C CG    . PHE D 22 ? 0.7016 0.7583 0.9029 -0.0850 -0.0128 0.0577  251 PHE E CG    
1370 C CD1   . PHE D 22 ? 0.8168 0.8432 0.9603 -0.0802 -0.0180 0.0472  251 PHE E CD1   
1371 C CD2   . PHE D 22 ? 0.7309 0.8269 0.9988 -0.0770 -0.0144 0.0740  251 PHE E CD2   
1372 C CE1   . PHE D 22 ? 0.8364 0.8655 0.9840 -0.0684 -0.0272 0.0545  251 PHE E CE1   
1373 C CE2   . PHE D 22 ? 0.8177 0.9180 1.0936 -0.0620 -0.0241 0.0787  251 PHE E CE2   
1374 C CZ    . PHE D 22 ? 0.8309 0.8946 1.0441 -0.0580 -0.0316 0.0696  251 PHE E CZ    
1375 N N     . GLU D 23 ? 0.9365 1.0196 1.2520 -0.1425 -0.0606 0.0758  252 GLU E N     
1376 C CA    . GLU D 23 ? 0.9015 1.0233 1.2977 -0.1545 -0.0835 0.0937  252 GLU E CA    
1377 C C     . GLU D 23 ? 0.9496 1.0433 1.3259 -0.1755 -0.1340 0.0833  252 GLU E C     
1378 O O     . GLU D 23 ? 0.9099 1.0241 1.3227 -0.1794 -0.1669 0.0926  252 GLU E O     
1379 C CB    . GLU D 23 ? 0.8521 1.0016 1.3111 -0.1656 -0.0621 0.1109  252 GLU E CB    
1380 C CG    . GLU D 23 ? 0.9007 1.1143 1.4501 -0.1573 -0.0447 0.1352  252 GLU E CG    
1381 C CD    . GLU D 23 ? 0.8495 1.0821 1.3896 -0.1300 0.0054  0.1389  252 GLU E CD    
1382 O OE1   . GLU D 23 ? 0.9477 1.1831 1.4857 -0.1326 0.0381  0.1470  252 GLU E OE1   
1383 O OE2   . GLU D 23 ? 0.8139 1.0553 1.3474 -0.1070 0.0102  0.1345  252 GLU E OE2   
1384 N N     . ARG D 24 ? 0.9731 1.0175 1.2886 -0.1873 -0.1407 0.0628  253 ARG E N     
1385 C CA    . ARG D 24 ? 1.1295 1.1358 1.4051 -0.2058 -0.1854 0.0460  253 ARG E CA    
1386 C C     . ARG D 24 ? 1.1446 1.1272 1.3443 -0.1946 -0.1963 0.0346  253 ARG E C     
1387 O O     . ARG D 24 ? 1.3064 1.2907 1.5056 -0.2017 -0.2354 0.0394  253 ARG E O     
1388 C CB    . ARG D 24 ? 1.1758 1.1326 1.4091 -0.2183 -0.1851 0.0241  253 ARG E CB    
1389 C CG    . ARG D 24 ? 1.2911 1.2457 1.5825 -0.2452 -0.2116 0.0292  253 ARG E CG    
1390 C CD    . ARG D 24 ? 1.4229 1.3169 1.6634 -0.2538 -0.2136 0.0030  253 ARG E CD    
1391 N NE    . ARG D 24 ? 1.4386 1.3210 1.6376 -0.2313 -0.1689 -0.0038 253 ARG E NE    
1392 C CZ    . ARG D 24 ? 1.4853 1.3707 1.7119 -0.2277 -0.1402 0.0069  253 ARG E CZ    
1393 N NH1   . ARG D 24 ? 1.4868 1.3712 1.7707 -0.2478 -0.1504 0.0204  253 ARG E NH1   
1394 N NH2   . ARG D 24 ? 1.4353 1.3212 1.6298 -0.2056 -0.1043 0.0050  253 ARG E NH2   
1395 N N     . GLN D 25 ? 1.1037 1.0650 1.2423 -0.1784 -0.1627 0.0223  254 GLN E N     
1396 C CA    . GLN D 25 ? 1.0377 0.9688 1.0954 -0.1720 -0.1674 0.0105  254 GLN E CA    
1397 C C     . GLN D 25 ? 0.9261 0.8725 0.9774 -0.1497 -0.1342 0.0190  254 GLN E C     
1398 O O     . GLN D 25 ? 0.8425 0.7883 0.8888 -0.1395 -0.0989 0.0133  254 GLN E O     
1399 C CB    . GLN D 25 ? 1.0436 0.9268 1.0303 -0.1774 -0.1588 -0.0177 254 GLN E CB    
1400 C CG    . GLN D 25 ? 1.1543 1.0087 1.1340 -0.1991 -0.1937 -0.0326 254 GLN E CG    
1401 C CD    . GLN D 25 ? 1.3230 1.1240 1.2165 -0.2002 -0.1867 -0.0649 254 GLN E CD    
1402 O OE1   . GLN D 25 ? 1.3595 1.1517 1.2389 -0.1876 -0.1499 -0.0759 254 GLN E OE1   
1403 N NE2   . GLN D 25 ? 1.4771 1.2427 1.3108 -0.2137 -0.2215 -0.0806 254 GLN E NE2   
1404 N N     . LYS D 26 ? 0.8900 0.8455 0.9402 -0.1430 -0.1501 0.0326  255 LYS E N     
1405 C CA    . LYS D 26 ? 0.9507 0.9118 0.9918 -0.1236 -0.1248 0.0397  255 LYS E CA    
1406 C C     . LYS D 26 ? 0.8903 0.8137 0.8495 -0.1237 -0.1066 0.0231  255 LYS E C     
1407 O O     . LYS D 26 ? 0.9308 0.8546 0.8820 -0.1113 -0.0771 0.0220  255 LYS E O     
1408 C CB    . LYS D 26 ? 1.0615 1.0344 1.1226 -0.1166 -0.1509 0.0594  255 LYS E CB    
1409 C CG    . LYS D 26 ? 1.1708 1.1862 1.3226 -0.1168 -0.1748 0.0771  255 LYS E CG    
1410 C CD    . LYS D 26 ? 1.1322 1.1916 1.3634 -0.1006 -0.1416 0.0857  255 LYS E CD    
1411 C CE    . LYS D 26 ? 1.1810 1.2860 1.5057 -0.1075 -0.1586 0.1005  255 LYS E CE    
1412 N NZ    . LYS D 26 ? 1.0879 1.1944 1.4252 -0.1276 -0.1550 0.0939  255 LYS E NZ    
1413 N N     . TYR D 27 ? 0.9411 0.8323 0.8408 -0.1382 -0.1238 0.0091  256 TYR E N     
1414 C CA    . TYR D 27 ? 0.9955 0.8548 0.8195 -0.1386 -0.1034 -0.0064 256 TYR E CA    
1415 C C     . TYR D 27 ? 0.9905 0.8285 0.7917 -0.1464 -0.0957 -0.0319 256 TYR E C     
1416 O O     . TYR D 27 ? 1.0451 0.8737 0.8519 -0.1589 -0.1233 -0.0386 256 TYR E O     
1417 C CB    . TYR D 27 ? 1.0865 0.9215 0.8465 -0.1460 -0.1279 0.0011  256 TYR E CB    
1418 C CG    . TYR D 27 ? 1.0610 0.9103 0.8447 -0.1356 -0.1340 0.0273  256 TYR E CG    
1419 C CD1   . TYR D 27 ? 1.0458 0.8928 0.8193 -0.1254 -0.1035 0.0322  256 TYR E CD1   
1420 C CD2   . TYR D 27 ? 1.1045 0.9691 0.9286 -0.1356 -0.1721 0.0469  256 TYR E CD2   
1421 C CE1   . TYR D 27 ? 1.0252 0.8782 0.8225 -0.1152 -0.1103 0.0541  256 TYR E CE1   
1422 C CE2   . TYR D 27 ? 1.0712 0.9456 0.9228 -0.1228 -0.1782 0.0697  256 TYR E CE2   
1423 C CZ    . TYR D 27 ? 1.0270 0.8922 0.8621 -0.1124 -0.1470 0.0725  256 TYR E CZ    
1424 O OH    . TYR D 27 ? 1.0057 0.8734 0.8685 -0.0994 -0.1552 0.0932  256 TYR E OH    
1425 N N     . LEU D 28 ? 0.9561 0.7873 0.7404 -0.1383 -0.0600 -0.0457 257 LEU E N     
1426 C CA    . LEU D 28 ? 1.0380 0.8436 0.7951 -0.1415 -0.0495 -0.0720 257 LEU E CA    
1427 C C     . LEU D 28 ? 1.1653 0.9434 0.8431 -0.1425 -0.0341 -0.0874 257 LEU E C     
1428 O O     . LEU D 28 ? 1.1338 0.9202 0.7959 -0.1370 -0.0134 -0.0776 257 LEU E O     
1429 C CB    . LEU D 28 ? 1.0784 0.8986 0.8807 -0.1298 -0.0207 -0.0753 257 LEU E CB    
1430 C CG    . LEU D 28 ? 0.9506 0.7961 0.8234 -0.1289 -0.0276 -0.0597 257 LEU E CG    
1431 C CD1   . LEU D 28 ? 1.0143 0.8637 0.9101 -0.1180 -0.0010 -0.0645 257 LEU E CD1   
1432 C CD2   . LEU D 28 ? 0.9915 0.8271 0.8827 -0.1438 -0.0574 -0.0619 257 LEU E CD2   
1433 N N     . SER D 29 ? 1.1809 0.9246 0.8101 -0.1502 -0.0430 -0.1121 258 SER E N     
1434 C CA    . SER D 29 ? 1.2567 0.9743 0.8171 -0.1474 -0.0156 -0.1352 258 SER E CA    
1435 C C     . SER D 29 ? 1.2632 0.9972 0.8636 -0.1319 0.0253  -0.1438 258 SER E C     
1436 O O     . SER D 29 ? 1.0966 0.8489 0.7647 -0.1255 0.0256  -0.1384 258 SER E O     
1437 C CB    . SER D 29 ? 1.3279 1.0024 0.8361 -0.1560 -0.0343 -0.1646 258 SER E CB    
1438 O OG    . SER D 29 ? 1.3103 0.9824 0.8771 -0.1534 -0.0397 -0.1762 258 SER E OG    
1439 N N     . VAL D 30 ? 1.2480 0.9753 0.8057 -0.1266 0.0598  -0.1567 259 VAL E N     
1440 C CA    . VAL D 30 ? 1.2452 0.9902 0.8454 -0.1118 0.0963  -0.1659 259 VAL E CA    
1441 C C     . VAL D 30 ? 1.2368 0.9688 0.8775 -0.1045 0.0892  -0.1849 259 VAL E C     
1442 O O     . VAL D 30 ? 1.1265 0.8802 0.8341 -0.0965 0.0906  -0.1742 259 VAL E O     
1443 C CB    . VAL D 30 ? 1.3110 1.0506 0.8603 -0.1084 0.1359  -0.1804 259 VAL E CB    
1444 C CG1   . VAL D 30 ? 1.3476 1.0989 0.9414 -0.0914 0.1705  -0.2002 259 VAL E CG1   
1445 C CG2   . VAL D 30 ? 1.3008 1.0616 0.8382 -0.1151 0.1482  -0.1530 259 VAL E CG2   
1446 N N     . GLN D 31 ? 1.2055 0.8973 0.8017 -0.1083 0.0780  -0.2119 260 GLN E N     
1447 C CA    . GLN D 31 ? 1.2580 0.9276 0.8878 -0.1013 0.0727  -0.2325 260 GLN E CA    
1448 C C     . GLN D 31 ? 1.1751 0.8623 0.8753 -0.1064 0.0458  -0.2078 260 GLN E C     
1449 O O     . GLN D 31 ? 1.1610 0.8547 0.9173 -0.0961 0.0531  -0.2057 260 GLN E O     
1450 C CB    . GLN D 31 ? 1.3976 1.0133 0.9611 -0.1068 0.0599  -0.2674 260 GLN E CB    
1451 C CG    . GLN D 31 ? 1.5935 1.1876 1.1289 -0.1286 0.0110  -0.2618 260 GLN E CG    
1452 C CD    . GLN D 31 ? 1.6212 1.2031 1.0690 -0.1411 -0.0003 -0.2604 260 GLN E CD    
1453 O OE1   . GLN D 31 ? 1.6914 1.2964 1.1135 -0.1382 0.0233  -0.2450 260 GLN E OE1   
1454 N NE2   . GLN D 31 ? 1.5562 1.0986 0.9563 -0.1569 -0.0406 -0.2746 260 GLN E NE2   
1455 N N     . ASP D 32 ? 1.1220 0.8184 0.8209 -0.1217 0.0155  -0.1871 261 ASP E N     
1456 C CA    . ASP D 32 ? 1.0893 0.8051 0.8545 -0.1274 -0.0052 -0.1637 261 ASP E CA    
1457 C C     . ASP D 32 ? 1.0039 0.7577 0.8194 -0.1143 0.0178  -0.1428 261 ASP E C     
1458 O O     . ASP D 32 ? 0.9994 0.7606 0.8657 -0.1109 0.0172  -0.1327 261 ASP E O     
1459 C CB    . ASP D 32 ? 1.1770 0.9027 0.9396 -0.1437 -0.0386 -0.1455 261 ASP E CB    
1460 C CG    . ASP D 32 ? 1.2516 0.9393 0.9751 -0.1606 -0.0739 -0.1632 261 ASP E CG    
1461 O OD1   . ASP D 32 ? 1.2973 0.9472 1.0097 -0.1615 -0.0766 -0.1892 261 ASP E OD1   
1462 O OD2   . ASP D 32 ? 1.3493 1.0424 1.0525 -0.1722 -0.1014 -0.1515 261 ASP E OD2   
1463 N N     . ARG D 33 ? 0.9837 0.7579 0.7805 -0.1081 0.0374  -0.1361 262 ARG E N     
1464 C CA    . ARG D 33 ? 0.8818 0.6878 0.7190 -0.0974 0.0548  -0.1188 262 ARG E CA    
1465 C C     . ARG D 33 ? 1.0030 0.8055 0.8679 -0.0841 0.0730  -0.1309 262 ARG E C     
1466 O O     . ARG D 33 ? 0.9284 0.7460 0.8362 -0.0780 0.0730  -0.1168 262 ARG E O     
1467 C CB    . ARG D 33 ? 0.9235 0.7457 0.7359 -0.0969 0.0677  -0.1096 262 ARG E CB    
1468 C CG    . ARG D 33 ? 0.9331 0.7843 0.7828 -0.0902 0.0745  -0.0895 262 ARG E CG    
1469 C CD    . ARG D 33 ? 1.0672 0.9252 0.8911 -0.0936 0.0793  -0.0788 262 ARG E CD    
1470 N NE    . ARG D 33 ? 0.9867 0.8423 0.7895 -0.0920 0.1048  -0.0904 262 ARG E NE    
1471 C CZ    . ARG D 33 ? 1.0807 0.9230 0.8323 -0.0993 0.1136  -0.0951 262 ARG E CZ    
1472 N NH1   . ARG D 33 ? 0.9998 0.8469 0.7446 -0.0967 0.1433  -0.1050 262 ARG E NH1   
1473 N NH2   . ARG D 33 ? 1.1068 0.9325 0.8155 -0.1092 0.0931  -0.0891 262 ARG E NH2   
1474 N N     . MET D 34 ? 1.1141 0.8948 0.9538 -0.0785 0.0875  -0.1571 263 MET E N     
1475 C CA    . MET D 34 ? 1.1448 0.9222 1.0191 -0.0628 0.1034  -0.1696 263 MET E CA    
1476 C C     . MET D 34 ? 1.1104 0.8674 1.0191 -0.0631 0.0828  -0.1667 263 MET E C     
1477 O O     . MET D 34 ? 1.0920 0.8586 1.0453 -0.0540 0.0831  -0.1545 263 MET E O     
1478 C CB    . MET D 34 ? 1.3113 1.0690 1.1535 -0.0545 0.1269  -0.2013 263 MET E CB    
1479 C CG    . MET D 34 ? 1.3720 1.1559 1.1974 -0.0516 0.1569  -0.2009 263 MET E CG    
1480 S SD    . MET D 34 ? 1.4085 1.1757 1.2028 -0.0388 0.1949  -0.2381 263 MET E SD    
1481 C CE    . MET D 34 ? 1.2875 1.1081 1.1257 -0.0336 0.2264  -0.2208 263 MET E CE    
1482 N N     . ASP D 35 ? 1.1021 0.8287 0.9893 -0.0755 0.0621  -0.1758 264 ASP E N     
1483 C CA    . ASP D 35 ? 1.1638 0.8677 1.0860 -0.0800 0.0417  -0.1705 264 ASP E CA    
1484 C C     . ASP D 35 ? 1.1279 0.8628 1.0927 -0.0834 0.0355  -0.1350 264 ASP E C     
1485 O O     . ASP D 35 ? 1.0941 0.8235 1.0953 -0.0776 0.0337  -0.1237 264 ASP E O     
1486 C CB    . ASP D 35 ? 1.2185 0.8910 1.1157 -0.0986 0.0149  -0.1808 264 ASP E CB    
1487 C CG    . ASP D 35 ? 1.3147 0.9470 1.1563 -0.0953 0.0195  -0.2200 264 ASP E CG    
1488 O OD1   . ASP D 35 ? 1.2095 0.8358 1.0496 -0.0761 0.0461  -0.2391 264 ASP E OD1   
1489 O OD2   . ASP D 35 ? 1.3878 0.9975 1.1882 -0.1114 -0.0030 -0.2306 264 ASP E OD2   
1490 N N     . LEU D 36 ? 0.9594 0.7244 0.9162 -0.0919 0.0326  -0.1171 265 LEU E N     
1491 C CA    . LEU D 36 ? 0.9038 0.6944 0.8955 -0.0955 0.0284  -0.0868 265 LEU E CA    
1492 C C     . LEU D 36 ? 0.8413 0.6490 0.8481 -0.0798 0.0450  -0.0775 265 LEU E C     
1493 O O     . LEU D 36 ? 0.9388 0.7496 0.9710 -0.0784 0.0429  -0.0586 265 LEU E O     
1494 C CB    . LEU D 36 ? 0.9118 0.7279 0.8959 -0.1051 0.0212  -0.0737 265 LEU E CB    
1495 C CG    . LEU D 36 ? 0.8445 0.6926 0.8617 -0.1056 0.0243  -0.0449 265 LEU E CG    
1496 C CD1   . LEU D 36 ? 0.8481 0.6909 0.9025 -0.1180 0.0128  -0.0297 265 LEU E CD1   
1497 C CD2   . LEU D 36 ? 0.8867 0.7591 0.8967 -0.1083 0.0207  -0.0373 265 LEU E CD2   
1498 N N     . ALA D 37 ? 0.8035 0.6203 0.7945 -0.0691 0.0604  -0.0902 266 ALA E N     
1499 C CA    . ALA D 37 ? 0.8085 0.6416 0.8182 -0.0560 0.0703  -0.0827 266 ALA E CA    
1500 C C     . ALA D 37 ? 0.7564 0.5682 0.7936 -0.0473 0.0654  -0.0847 266 ALA E C     
1501 O O     . ALA D 37 ? 0.7790 0.5960 0.8356 -0.0419 0.0605  -0.0666 266 ALA E O     
1502 C CB    . ALA D 37 ? 0.9030 0.7508 0.9008 -0.0493 0.0870  -0.0958 266 ALA E CB    
1503 N N     . ALA D 38 ? 0.8707 0.6545 0.9052 -0.0451 0.0658  -0.1075 267 ALA E N     
1504 C CA    . ALA D 38 ? 0.9376 0.6949 1.0020 -0.0337 0.0609  -0.1131 267 ALA E CA    
1505 C C     . ALA D 38 ? 0.8829 0.6219 0.9631 -0.0443 0.0417  -0.0897 267 ALA E C     
1506 O O     . ALA D 38 ? 0.8729 0.6060 0.9782 -0.0367 0.0351  -0.0727 267 ALA E O     
1507 C CB    . ALA D 38 ? 0.9459 0.6731 0.9994 -0.0273 0.0683  -0.1473 267 ALA E CB    
1508 N N     . ALA D 39 ? 0.9716 0.7064 1.0379 -0.0632 0.0325  -0.0848 268 ALA E N     
1509 C CA    . ALA D 39 ? 0.9906 0.7163 1.0771 -0.0779 0.0181  -0.0586 268 ALA E CA    
1510 C C     . ALA D 39 ? 0.9719 0.7237 1.0675 -0.0743 0.0234  -0.0268 268 ALA E C     
1511 O O     . ALA D 39 ? 0.9589 0.6943 1.0726 -0.0767 0.0159  -0.0049 268 ALA E O     
1512 C CB    . ALA D 39 ? 0.9411 0.6752 1.0191 -0.0981 0.0093  -0.0567 268 ALA E CB    
1513 N N     . LEU D 40 ? 0.8163 0.6032 0.8941 -0.0684 0.0356  -0.0250 269 LEU E N     
1514 C CA    . LEU D 40 ? 0.8540 0.6646 0.9273 -0.0663 0.0412  0.0003  269 LEU E CA    
1515 C C     . LEU D 40 ? 0.9437 0.7567 1.0151 -0.0496 0.0416  0.0006  269 LEU E C     
1516 O O     . LEU D 40 ? 0.8965 0.7232 0.9543 -0.0468 0.0433  0.0186  269 LEU E O     
1517 C CB    . LEU D 40 ? 0.7860 0.6279 0.8430 -0.0706 0.0506  -0.0004 269 LEU E CB    
1518 C CG    . LEU D 40 ? 0.8295 0.6762 0.8969 -0.0871 0.0456  0.0036  269 LEU E CG    
1519 C CD1   . LEU D 40 ? 0.7546 0.6339 0.8148 -0.0883 0.0530  0.0077  269 LEU E CD1   
1520 C CD2   . LEU D 40 ? 0.8155 0.6536 0.9080 -0.0989 0.0412  0.0285  269 LEU E CD2   
1521 N N     . ASN D 41 ? 0.9058 0.7063 0.9911 -0.0381 0.0399  -0.0202 270 ASN E N     
1522 C CA    . ASN D 41 ? 0.8604 0.6685 0.9579 -0.0223 0.0373  -0.0215 270 ASN E CA    
1523 C C     . ASN D 41 ? 0.7610 0.6014 0.8406 -0.0214 0.0457  -0.0239 270 ASN E C     
1524 O O     . ASN D 41 ? 0.7769 0.6268 0.8537 -0.0154 0.0384  -0.0129 270 ASN E O     
1525 C CB    . ASN D 41 ? 0.9988 0.7890 1.1059 -0.0178 0.0211  0.0036  270 ASN E CB    
1526 C CG    . ASN D 41 ? 1.1369 0.9383 1.2572 -0.0025 0.0115  0.0050  270 ASN E CG    
1527 O OD1   . ASN D 41 ? 1.2064 1.0190 1.3539 0.0083  0.0161  -0.0164 270 ASN E OD1   
1528 N ND2   . ASN D 41 ? 1.1899 0.9906 1.2909 -0.0023 -0.0014 0.0300  270 ASN E ND2   
1529 N N     . LEU D 42 ? 0.8022 0.6548 0.8672 -0.0280 0.0580  -0.0383 271 LEU E N     
1530 C CA    . LEU D 42 ? 0.7517 0.6287 0.8023 -0.0284 0.0659  -0.0419 271 LEU E CA    
1531 C C     . LEU D 42 ? 0.8008 0.6850 0.8592 -0.0257 0.0783  -0.0638 271 LEU E C     
1532 O O     . LEU D 42 ? 0.7199 0.5896 0.7840 -0.0241 0.0837  -0.0790 271 LEU E O     
1533 C CB    . LEU D 42 ? 0.8286 0.7123 0.8553 -0.0391 0.0698  -0.0345 271 LEU E CB    
1534 C CG    . LEU D 42 ? 0.8955 0.7808 0.9135 -0.0417 0.0665  -0.0123 271 LEU E CG    
1535 C CD1   . LEU D 42 ? 0.8332 0.7279 0.8458 -0.0513 0.0715  -0.0066 271 LEU E CD1   
1536 C CD2   . LEU D 42 ? 0.8563 0.7512 0.8589 -0.0344 0.0655  -0.0071 271 LEU E CD2   
1537 N N     . THR D 43 ? 0.7136 0.6180 0.7690 -0.0264 0.0845  -0.0657 272 THR E N     
1538 C CA    . THR D 43 ? 0.6831 0.5974 0.7419 -0.0274 0.1014  -0.0818 272 THR E CA    
1539 C C     . THR D 43 ? 0.7250 0.6328 0.7458 -0.0386 0.1078  -0.0843 272 THR E C     
1540 O O     . THR D 43 ? 0.7618 0.6679 0.7640 -0.0448 0.0995  -0.0725 272 THR E O     
1541 C CB    . THR D 43 ? 0.6268 0.5638 0.7028 -0.0275 0.1045  -0.0801 272 THR E CB    
1542 O OG1   . THR D 43 ? 0.5835 0.5208 0.6307 -0.0359 0.0997  -0.0701 272 THR E OG1   
1543 C CG2   . THR D 43 ? 0.5900 0.5359 0.7055 -0.0176 0.0906  -0.0757 272 THR E CG2   
1544 N N     . ASP D 44 ? 0.7307 0.6361 0.7403 -0.0405 0.1235  -0.0995 273 ASP E N     
1545 C CA    . ASP D 44 ? 0.8223 0.7194 0.7896 -0.0516 0.1263  -0.1008 273 ASP E CA    
1546 C C     . ASP D 44 ? 0.6929 0.6017 0.6499 -0.0583 0.1217  -0.0846 273 ASP E C     
1547 O O     . ASP D 44 ? 0.7607 0.6623 0.6918 -0.0655 0.1130  -0.0778 273 ASP E O     
1548 C CB    . ASP D 44 ? 0.9130 0.8051 0.8603 -0.0521 0.1478  -0.1192 273 ASP E CB    
1549 C CG    . ASP D 44 ? 1.1767 1.0494 1.0686 -0.0635 0.1447  -0.1230 273 ASP E CG    
1550 O OD1   . ASP D 44 ? 1.3649 1.2152 1.2430 -0.0652 0.1308  -0.1311 273 ASP E OD1   
1551 O OD2   . ASP D 44 ? 1.1921 1.0702 1.0560 -0.0719 0.1523  -0.1155 273 ASP E OD2   
1552 N N     . THR D 45 ? 0.6730 0.5979 0.6522 -0.0560 0.1260  -0.0799 274 THR E N     
1553 C CA    . THR D 45 ? 0.7130 0.6425 0.6836 -0.0618 0.1222  -0.0682 274 THR E CA    
1554 C C     . THR D 45 ? 0.6841 0.6096 0.6518 -0.0580 0.1060  -0.0577 274 THR E C     
1555 O O     . THR D 45 ? 0.6902 0.6113 0.6412 -0.0610 0.1012  -0.0496 274 THR E O     
1556 C CB    . THR D 45 ? 0.7293 0.6745 0.7310 -0.0618 0.1275  -0.0684 274 THR E CB    
1557 O OG1   . THR D 45 ? 0.7485 0.7033 0.7574 -0.0659 0.1491  -0.0761 274 THR E OG1   
1558 C CG2   . THR D 45 ? 0.6651 0.6080 0.6616 -0.0681 0.1202  -0.0584 274 THR E CG2   
1559 N N     . GLN D 46 ? 0.6732 0.6003 0.6581 -0.0504 0.0989  -0.0567 275 GLN E N     
1560 C CA    . GLN D 46 ? 0.7024 0.6267 0.6807 -0.0465 0.0899  -0.0463 275 GLN E CA    
1561 C C     . GLN D 46 ? 0.7237 0.6450 0.6912 -0.0513 0.0887  -0.0414 275 GLN E C     
1562 O O     . GLN D 46 ? 0.6888 0.6138 0.6516 -0.0500 0.0866  -0.0329 275 GLN E O     
1563 C CB    . GLN D 46 ? 0.6543 0.5760 0.6452 -0.0402 0.0835  -0.0426 275 GLN E CB    
1564 C CG    . GLN D 46 ? 0.6227 0.5483 0.6253 -0.0348 0.0765  -0.0440 275 GLN E CG    
1565 C CD    . GLN D 46 ? 0.7618 0.6810 0.7728 -0.0282 0.0657  -0.0366 275 GLN E CD    
1566 O OE1   . GLN D 46 ? 0.7640 0.6768 0.7912 -0.0264 0.0657  -0.0374 275 GLN E OE1   
1567 N NE2   . GLN D 46 ? 0.7142 0.6303 0.7096 -0.0244 0.0547  -0.0293 275 GLN E NE2   
1568 N N     . VAL D 47 ? 0.7028 0.6169 0.6688 -0.0563 0.0889  -0.0483 276 VAL E N     
1569 C CA    . VAL D 47 ? 0.6597 0.5702 0.6184 -0.0633 0.0813  -0.0443 276 VAL E CA    
1570 C C     . VAL D 47 ? 0.7528 0.6633 0.6908 -0.0683 0.0796  -0.0426 276 VAL E C     
1571 O O     . VAL D 47 ? 0.7789 0.6936 0.7191 -0.0710 0.0695  -0.0331 276 VAL E O     
1572 C CB    . VAL D 47 ? 0.6918 0.5868 0.6493 -0.0687 0.0768  -0.0545 276 VAL E CB    
1573 C CG1   . VAL D 47 ? 0.7134 0.6050 0.6642 -0.0790 0.0626  -0.0504 276 VAL E CG1   
1574 C CG2   . VAL D 47 ? 0.7505 0.6397 0.7316 -0.0641 0.0751  -0.0520 276 VAL E CG2   
1575 N N     . LYS D 48 ? 0.6892 0.5955 0.6100 -0.0705 0.0886  -0.0495 277 LYS E N     
1576 C CA    . LYS D 48 ? 0.7311 0.6321 0.6270 -0.0769 0.0850  -0.0432 277 LYS E CA    
1577 C C     . LYS D 48 ? 0.7506 0.6578 0.6596 -0.0713 0.0797  -0.0303 277 LYS E C     
1578 O O     . LYS D 48 ? 0.7735 0.6782 0.6768 -0.0725 0.0686  -0.0204 277 LYS E O     
1579 C CB    . LYS D 48 ? 0.8268 0.7235 0.7031 -0.0819 0.1005  -0.0485 277 LYS E CB    
1580 C CG    . LYS D 48 ? 0.8894 0.7736 0.7264 -0.0917 0.0981  -0.0406 277 LYS E CG    
1581 C CD    . LYS D 48 ? 0.8927 0.7772 0.7210 -0.0978 0.1168  -0.0372 277 LYS E CD    
1582 C CE    . LYS D 48 ? 0.9880 0.8883 0.8477 -0.0942 0.1363  -0.0487 277 LYS E CE    
1583 N NZ    . LYS D 48 ? 1.1508 1.0569 1.0156 -0.1027 0.1528  -0.0415 277 LYS E NZ    
1584 N N     . THR D 49 ? 0.8200 0.7326 0.7454 -0.0643 0.0862  -0.0319 278 THR E N     
1585 C CA    . THR D 49 ? 0.7830 0.6945 0.7149 -0.0572 0.0832  -0.0255 278 THR E CA    
1586 C C     . THR D 49 ? 0.7878 0.7079 0.7329 -0.0493 0.0782  -0.0184 278 THR E C     
1587 O O     . THR D 49 ? 0.8564 0.7758 0.8062 -0.0449 0.0726  -0.0109 278 THR E O     
1588 C CB    . THR D 49 ? 0.7627 0.6752 0.7037 -0.0526 0.0873  -0.0323 278 THR E CB    
1589 O OG1   . THR D 49 ? 0.7763 0.6897 0.7191 -0.0609 0.0938  -0.0378 278 THR E OG1   
1590 C CG2   . THR D 49 ? 0.8363 0.7390 0.7758 -0.0461 0.0836  -0.0317 278 THR E CG2   
1591 N N     . TRP D 50 ? 0.7261 0.6555 0.6823 -0.0475 0.0809  -0.0191 279 TRP E N     
1592 C CA    . TRP D 50 ? 0.6606 0.6039 0.6361 -0.0429 0.0809  -0.0099 279 TRP E CA    
1593 C C     . TRP D 50 ? 0.6788 0.6278 0.6652 -0.0470 0.0693  -0.0022 279 TRP E C     
1594 O O     . TRP D 50 ? 0.7164 0.6733 0.7185 -0.0383 0.0684  0.0047  279 TRP E O     
1595 C CB    . TRP D 50 ? 0.6529 0.6005 0.6376 -0.0470 0.0830  -0.0083 279 TRP E CB    
1596 C CG    . TRP D 50 ? 0.7034 0.6689 0.7117 -0.0439 0.0883  0.0045  279 TRP E CG    
1597 C CD1   . TRP D 50 ? 0.7409 0.7130 0.7473 -0.0345 0.1023  0.0098  279 TRP E CD1   
1598 C CD2   . TRP D 50 ? 0.7426 0.7235 0.7809 -0.0511 0.0809  0.0143  279 TRP E CD2   
1599 N NE1   . TRP D 50 ? 0.6927 0.6865 0.7285 -0.0350 0.1096  0.0233  279 TRP E NE1   
1600 C CE2   . TRP D 50 ? 0.7093 0.7111 0.7717 -0.0455 0.0952  0.0269  279 TRP E CE2   
1601 C CE3   . TRP D 50 ? 0.8926 0.8714 0.9383 -0.0626 0.0625  0.0138  279 TRP E CE3   
1602 C CZ2   . TRP D 50 ? 0.6741 0.7006 0.7809 -0.0517 0.0927  0.0406  279 TRP E CZ2   
1603 C CZ3   . TRP D 50 ? 0.8074 0.8061 0.8925 -0.0694 0.0537  0.0259  279 TRP E CZ3   
1604 C CH2   . TRP D 50 ? 0.7287 0.7541 0.8505 -0.0642 0.0692  0.0400  279 TRP E CH2   
1605 N N     . TYR D 51 ? 0.7230 0.6640 0.6973 -0.0593 0.0587  -0.0052 280 TYR E N     
1606 C CA    . TYR D 51 ? 0.6830 0.6251 0.6596 -0.0661 0.0404  0.0016  280 TYR E CA    
1607 C C     . TYR D 51 ? 0.6298 0.5659 0.5989 -0.0602 0.0352  0.0089  280 TYR E C     
1608 O O     . TYR D 51 ? 0.6979 0.6435 0.6892 -0.0566 0.0215  0.0203  280 TYR E O     
1609 C CB    . TYR D 51 ? 0.7642 0.6890 0.7102 -0.0802 0.0296  -0.0072 280 TYR E CB    
1610 C CG    . TYR D 51 ? 0.6843 0.6134 0.6499 -0.0896 0.0148  -0.0070 280 TYR E CG    
1611 C CD1   . TYR D 51 ? 0.7606 0.6950 0.7376 -0.0970 -0.0102 0.0019  280 TYR E CD1   
1612 C CD2   . TYR D 51 ? 0.6829 0.6088 0.6595 -0.0923 0.0220  -0.0142 280 TYR E CD2   
1613 C CE1   . TYR D 51 ? 0.7600 0.6985 0.7618 -0.1088 -0.0279 0.0026  280 TYR E CE1   
1614 C CE2   . TYR D 51 ? 0.6851 0.6096 0.6822 -0.1040 0.0061  -0.0133 280 TYR E CE2   
1615 C CZ    . TYR D 51 ? 0.7414 0.6731 0.7527 -0.1134 -0.0190 -0.0054 280 TYR E CZ    
1616 O OH    . TYR D 51 ? 0.7833 0.7147 0.8226 -0.1280 -0.0390 -0.0037 280 TYR E OH    
1617 N N     . GLN D 52 ? 0.6762 0.5967 0.6205 -0.0593 0.0447  0.0039  281 GLN E N     
1618 C CA    . GLN D 52 ? 0.7619 0.6698 0.6988 -0.0560 0.0374  0.0132  281 GLN E CA    
1619 C C     . GLN D 52 ? 0.7341 0.6517 0.7057 -0.0386 0.0400  0.0173  281 GLN E C     
1620 O O     . GLN D 52 ? 0.7001 0.6200 0.6908 -0.0319 0.0269  0.0285  281 GLN E O     
1621 C CB    . GLN D 52 ? 0.7550 0.6435 0.6635 -0.0622 0.0470  0.0098  281 GLN E CB    
1622 C CG    . GLN D 52 ? 0.7850 0.6533 0.6812 -0.0634 0.0363  0.0240  281 GLN E CG    
1623 C CD    . GLN D 52 ? 0.8870 0.7492 0.7646 -0.0702 0.0153  0.0375  281 GLN E CD    
1624 O OE1   . GLN D 52 ? 0.8682 0.7269 0.7120 -0.0830 0.0133  0.0345  281 GLN E OE1   
1625 N NE2   . GLN D 52 ? 0.8854 0.7437 0.7834 -0.0607 -0.0024 0.0519  281 GLN E NE2   
1626 N N     . ASN D 53 ? 0.7741 0.6963 0.7522 -0.0301 0.0567  0.0077  282 ASN E N     
1627 C CA    . ASN D 53 ? 0.7413 0.6711 0.7431 -0.0120 0.0653  0.0071  282 ASN E CA    
1628 C C     . ASN D 53 ? 0.7775 0.7358 0.8197 -0.0068 0.0618  0.0179  282 ASN E C     
1629 O O     . ASN D 53 ? 0.7256 0.6910 0.7973 0.0076  0.0600  0.0237  282 ASN E O     
1630 C CB    . ASN D 53 ? 0.6799 0.6070 0.6676 -0.0071 0.0813  -0.0051 282 ASN E CB    
1631 C CG    . ASN D 53 ? 0.6707 0.5708 0.6346 -0.0091 0.0793  -0.0143 282 ASN E CG    
1632 O OD1   . ASN D 53 ? 0.6355 0.5175 0.6001 -0.0060 0.0719  -0.0117 282 ASN E OD1   
1633 N ND2   . ASN D 53 ? 0.6718 0.5677 0.6198 -0.0142 0.0832  -0.0235 282 ASN E ND2   
1634 N N     . ARG D 54 ? 0.6849 0.6586 0.7342 -0.0196 0.0574  0.0214  283 ARG E N     
1635 C CA    . ARG D 54 ? 0.6844 0.6890 0.7808 -0.0182 0.0549  0.0324  283 ARG E CA    
1636 C C     . ARG D 54 ? 0.7644 0.7743 0.8861 -0.0173 0.0304  0.0443  283 ARG E C     
1637 O O     . ARG D 54 ? 0.7169 0.7551 0.8923 -0.0068 0.0297  0.0543  283 ARG E O     
1638 C CB    . ARG D 54 ? 0.7111 0.7234 0.8087 -0.0347 0.0534  0.0326  283 ARG E CB    
1639 C CG    . ARG D 54 ? 0.7516 0.7990 0.9067 -0.0367 0.0527  0.0463  283 ARG E CG    
1640 C CD    . ARG D 54 ? 0.7257 0.7966 0.9065 -0.0223 0.0830  0.0507  283 ARG E CD    
1641 N NE    . ARG D 54 ? 0.7881 0.8996 1.0368 -0.0247 0.0834  0.0671  283 ARG E NE    
1642 C CZ    . ARG D 54 ? 0.8729 1.0113 1.1738 -0.0120 0.0803  0.0755  283 ARG E CZ    
1643 N NH1   . ARG D 54 ? 0.8315 1.0118 1.2030 -0.0175 0.0798  0.0915  283 ARG E NH1   
1644 N NH2   . ARG D 54 ? 0.9482 1.0728 1.2388 0.0060  0.0770  0.0693  283 ARG E NH2   
1645 N N     . ARG D 55 ? 0.7576 0.7420 0.8420 -0.0283 0.0101  0.0449  284 ARG E N     
1646 C CA    . ARG D 55 ? 0.7310 0.7153 0.8300 -0.0292 -0.0191 0.0591  284 ARG E CA    
1647 C C     . ARG D 55 ? 0.7115 0.6921 0.8352 -0.0076 -0.0170 0.0653  284 ARG E C     
1648 O O     . ARG D 55 ? 0.8501 0.8436 1.0153 0.0005  -0.0373 0.0794  284 ARG E O     
1649 C CB    . ARG D 55 ? 0.8531 0.8056 0.8922 -0.0464 -0.0389 0.0598  284 ARG E CB    
1650 C CG    . ARG D 55 ? 0.8666 0.8175 0.8817 -0.0659 -0.0482 0.0522  284 ARG E CG    
1651 C CD    . ARG D 55 ? 0.9371 0.8574 0.8902 -0.0806 -0.0691 0.0537  284 ARG E CD    
1652 N NE    . ARG D 55 ? 0.9027 0.7983 0.8035 -0.0836 -0.0463 0.0446  284 ARG E NE    
1653 C CZ    . ARG D 55 ? 0.9277 0.8186 0.8055 -0.0899 -0.0262 0.0271  284 ARG E CZ    
1654 N NH1   . ARG D 55 ? 0.7997 0.6962 0.6832 -0.0973 -0.0304 0.0161  284 ARG E NH1   
1655 N NH2   . ARG D 55 ? 0.8807 0.7594 0.7330 -0.0896 -0.0036 0.0214  284 ARG E NH2   
1656 N N     . THR D 56 ? 0.7370 0.6978 0.8377 0.0015  0.0045  0.0541  285 THR E N     
1657 C CA    . THR D 56 ? 0.8208 0.7681 0.9394 0.0227  0.0078  0.0548  285 THR E CA    
1658 C C     . THR D 56 ? 0.8358 0.8187 1.0162 0.0440  0.0226  0.0547  285 THR E C     
1659 O O     . THR D 56 ? 0.8122 0.8036 1.0389 0.0608  0.0120  0.0643  285 THR E O     
1660 C CB    . THR D 56 ? 0.7668 0.6843 0.8459 0.0245  0.0265  0.0389  285 THR E CB    
1661 O OG1   . THR D 56 ? 0.8849 0.7778 0.9189 0.0038  0.0145  0.0431  285 THR E OG1   
1662 C CG2   . THR D 56 ? 0.7264 0.6226 0.8215 0.0470  0.0305  0.0344  285 THR E CG2   
1663 N N     . LYS D 57 ? 0.9024 0.9053 1.0828 0.0436  0.0488  0.0446  286 LYS E N     
1664 C CA    . LYS D 57 ? 0.8914 0.9310 1.1241 0.0615  0.0718  0.0450  286 LYS E CA    
1665 C C     . LYS D 57 ? 0.8762 0.9537 1.1772 0.0603  0.0518  0.0641  286 LYS E C     
1666 O O     . LYS D 57 ? 0.6857 0.7855 1.0470 0.0824  0.0553  0.0699  286 LYS E O     
1667 C CB    . LYS D 57 ? 0.8739 0.9239 1.0823 0.0528  0.0972  0.0373  286 LYS E CB    
1668 C CG    . LYS D 57 ? 0.9485 1.0347 1.1975 0.0693  0.1298  0.0384  286 LYS E CG    
1669 C CD    . LYS D 57 ? 0.8703 0.9682 1.0977 0.0560  0.1500  0.0393  286 LYS E CD    
1670 C CE    . LYS D 57 ? 0.8553 0.9973 1.1331 0.0673  0.1816  0.0484  286 LYS E CE    
1671 N NZ    . LYS D 57 ? 0.8448 0.9890 1.0906 0.0542  0.2009  0.0519  286 LYS E NZ    
1672 N N     . TRP D 58 ? 0.7828 0.8647 1.0747 0.0349  0.0278  0.0726  287 TRP E N     
1673 C CA    . TRP D 58 ? 0.8399 0.9569 1.1948 0.0285  0.0024  0.0901  287 TRP E CA    
1674 C C     . TRP D 58 ? 0.8695 0.9795 1.2516 0.0414  -0.0281 0.1023  287 TRP E C     
1675 O O     . TRP D 58 ? 0.8458 0.9939 1.3062 0.0508  -0.0408 0.1163  287 TRP E O     
1676 C CB    . TRP D 58 ? 0.8702 0.9821 1.1983 -0.0018 -0.0205 0.0920  287 TRP E CB    
1677 C CG    . TRP D 58 ? 0.9253 1.0649 1.3103 -0.0122 -0.0573 0.1087  287 TRP E CG    
1678 C CD1   . TRP D 58 ? 1.0148 1.2062 1.4872 -0.0115 -0.0547 0.1209  287 TRP E CD1   
1679 C CD2   . TRP D 58 ? 1.1008 1.2180 1.4593 -0.0261 -0.1042 0.1161  287 TRP E CD2   
1680 N NE1   . TRP D 58 ? 1.1604 1.3644 1.6694 -0.0245 -0.1012 0.1346  287 TRP E NE1   
1681 C CE2   . TRP D 58 ? 1.1802 1.3368 1.6147 -0.0333 -0.1336 0.1315  287 TRP E CE2   
1682 C CE3   . TRP D 58 ? 1.2256 1.2942 1.5025 -0.0343 -0.1235 0.1125  287 TRP E CE3   
1683 C CZ2   . TRP D 58 ? 1.3390 1.4835 1.7637 -0.0478 -0.1868 0.1417  287 TRP E CZ2   
1684 C CZ3   . TRP D 58 ? 1.3297 1.3857 1.5908 -0.0479 -0.1705 0.1237  287 TRP E CZ3   
1685 C CH2   . TRP D 58 ? 1.3776 1.4689 1.7086 -0.0543 -0.2043 0.1374  287 TRP E CH2   
1686 N N     . LYS D 59 ? 0.9118 0.9744 1.2363 0.0425  -0.0401 0.0994  288 LYS E N     
1687 C CA    . LYS D 59 ? 1.0435 1.0929 1.3925 0.0572  -0.0678 0.1136  288 LYS E CA    
1688 C C     . LYS D 59 ? 0.9657 1.0347 1.3818 0.0916  -0.0449 0.1104  288 LYS E C     
1689 O O     . LYS D 59 ? 0.8353 0.9234 1.3179 0.1071  -0.0668 0.1259  288 LYS E O     
1690 C CB    . LYS D 59 ? 1.1621 1.1545 1.4343 0.0476  -0.0841 0.1154  288 LYS E CB    
1691 C CG    . LYS D 59 ? 1.3458 1.3254 1.5669 0.0182  -0.1151 0.1243  288 LYS E CG    
1692 C CD    . LYS D 59 ? 1.5308 1.4581 1.6695 0.0048  -0.1234 0.1275  288 LYS E CD    
1693 C CE    . LYS D 59 ? 1.5877 1.5040 1.6595 -0.0229 -0.1267 0.1210  288 LYS E CE    
1694 N NZ    . LYS D 59 ? 1.5869 1.4592 1.5830 -0.0354 -0.1233 0.1232  288 LYS E NZ    
1695 N N     . ARG D 60 ? 0.9632 1.0288 1.3631 0.1041  -0.0022 0.0901  289 ARG E N     
1696 C CA    . ARG D 60 ? 1.0424 1.1247 1.4957 0.1381  0.0271  0.0812  289 ARG E CA    
1697 C C     . ARG D 60 ? 1.0213 1.1719 1.5673 0.1467  0.0390  0.0918  289 ARG E C     
1698 O O     . ARG D 60 ? 0.9722 1.1459 1.5883 0.1770  0.0512  0.0926  289 ARG E O     
1699 C CB    . ARG D 60 ? 1.1173 1.1783 1.5198 0.1471  0.0689  0.0553  289 ARG E CB    
1700 C CG    . ARG D 60 ? 1.2037 1.2005 1.5438 0.1510  0.0631  0.0416  289 ARG E CG    
1701 C CD    . ARG D 60 ? 1.2960 1.2739 1.5981 0.1654  0.1006  0.0142  289 ARG E CD    
1702 N NE    . ARG D 60 ? 1.3122 1.3067 1.5740 0.1462  0.1203  0.0082  289 ARG E NE    
1703 C CZ    . ARG D 60 ? 1.3717 1.3513 1.5855 0.1508  0.1478  -0.0122 289 ARG E CZ    
1704 N NH1   . ARG D 60 ? 1.3660 1.3076 1.5555 0.1721  0.1591  -0.0340 289 ARG E NH1   
1705 N NH2   . ARG D 60 ? 1.3412 1.3397 1.5282 0.1333  0.1607  -0.0109 289 ARG E NH2   
1706 N N     . GLN D 61 ? 1.0169 1.1993 1.5683 0.1204  0.0365  0.0999  290 GLN E N     
1707 C CA    . GLN D 61 ? 1.0246 1.2740 1.6701 0.1214  0.0447  0.1140  290 GLN E CA    
1708 C C     . GLN D 61 ? 0.9354 1.2069 1.6515 0.1199  -0.0047 0.1365  290 GLN E C     
1709 O O     . GLN D 61 ? 0.9439 1.2595 1.7567 0.1436  0.0002  0.1458  290 GLN E O     
1710 C CB    . GLN D 61 ? 1.1604 1.4324 1.7944 0.0915  0.0549  0.1173  290 GLN E CB    
1711 C CG    . GLN D 61 ? 1.1631 1.4582 1.7967 0.0988  0.1110  0.1089  290 GLN E CG    
1712 C CD    . GLN D 61 ? 1.1297 1.3740 1.6602 0.0986  0.1339  0.0876  290 GLN E CD    
1713 O OE1   . GLN D 61 ? 0.9512 1.1863 1.4351 0.0770  0.1417  0.0860  290 GLN E OE1   
1714 N NE2   . GLN D 61 ? 1.1853 1.3948 1.6837 0.1230  0.1423  0.0714  290 GLN E NE2   
1715 N N     . THR D 62 ? 0.9248 1.1667 1.5929 0.0930  -0.0519 0.1449  291 THR E N     
1716 C CA    . THR D 62 ? 1.0206 1.2758 1.7391 0.0878  -0.1072 0.1670  291 THR E CA    
1717 C C     . THR D 62 ? 1.1188 1.3672 1.8836 0.1225  -0.1169 0.1742  291 THR E C     
1718 O O     . THR D 62 ? 1.1770 1.4731 2.0476 0.1388  -0.1318 0.1900  291 THR E O     
1719 C CB    . THR D 62 ? 1.0679 1.2759 1.6989 0.0573  -0.1527 0.1708  291 THR E CB    
1720 O OG1   . THR D 62 ? 1.1179 1.3197 1.6951 0.0299  -0.1378 0.1582  291 THR E OG1   
1721 C CG2   . THR D 62 ? 1.0764 1.3023 1.7561 0.0470  -0.2133 0.1938  291 THR E CG2   
1722 N N     . ALA D 63 ? 1.1419 1.3297 1.8311 0.1323  -0.1110 0.1636  292 ALA E N     
1723 C CA    . ALA D 63 ? 1.1441 1.3113 1.8648 0.1676  -0.1101 0.1643  292 ALA E CA    
1724 C C     . ALA D 63 ? 1.0600 1.2868 1.9136 0.1951  -0.1181 0.1792  292 ALA E C     
1725 O O     . ALA D 63 ? 1.0410 1.2671 1.9336 0.1970  -0.1711 0.2031  292 ALA E O     
1726 C CB    . ALA D 63 ? 1.1445 1.2855 1.8231 0.1852  -0.0567 0.1362  292 ALA E CB    
# 
