data_8R73
# 
_entry.id   8R73 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R73         pdb_00008r73 10.2210/pdb8r73/pdb 
WWPDB D_1292133811 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2024-12-04 ? 
2 'Structure model' 1 1 2025-02-05 ? 
3 'Structure model' 1 2 2025-02-26 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Structure summary'   
2 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' struct          
2 3 'Structure model' citation        
3 3 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_struct.title'                  
2 3 'Structure model' '_citation.country'              
3 3 'Structure model' '_citation.journal_abbrev'       
4 3 'Structure model' '_citation.journal_id_ASTM'      
5 3 'Structure model' '_citation.journal_id_CSD'       
6 3 'Structure model' '_citation.journal_id_ISSN'      
7 3 'Structure model' '_citation.pdbx_database_id_DOI' 
8 3 'Structure model' '_citation.title'                
9 3 'Structure model' '_citation.year'                 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R73 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              alan.cartmell@york.ac.uk 
_pdbx_contact_author.name_first         Alan 
_pdbx_contact_author.name_last          Cartmell 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-5512-249X 
# 
_audit_author.name               'Cartmell, A.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0002-5512-249X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Proc.Natl.Acad.Sci.USA 
_citation.journal_id_ASTM           PNASA6 
_citation.journal_id_CSD            0040 
_citation.journal_id_ISSN           1091-6490 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Bacterial polysaccharide lyase family 33: Specificity from an evolutionarily conserved binding tunnel' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1073/pnas.2421623122 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Loiodice, M.'   1  ? 
primary 'Drula, E.'      2  ? 
primary 'McIver, Z.'     3  ? 
primary 'Antonyuk, S.'   4  ? 
primary 'Basle, A.'      5  ? 
primary 'Lima, M.'       6  ? 
primary 'Yates, E.A.'    7  ? 
primary 'Byrne, D.P.'    8  ? 
primary 'Coughlan, J.'   9  ? 
primary 'Leech, A.'      10 ? 
primary 'Mesdaghi, S.'   11 ? 
primary 'Rigden, D.J.'   12 ? 
primary 'Drouillard, S.' 13 ? 
primary 'Helbert, W.'    14 ? 
primary 'Henrissat, B.'  15 ? 
primary 'Terrapon, N.'   16 ? 
primary 'Wright, G.S.A.' 17 ? 
primary 'Couturier, M.'  18 ? 
primary 'Cartmell, A.'   19 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Heparinase II/III-like protein' 72777.875 1   ? ? ? ? 
2 non-polymer syn 'ZINC ION'                       65.409    1   ? ? ? ? 
3 water       nat water                            18.015    312 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGSSHHHHHHSSGPQQGLRYTERNLLQKAAGSEEQLKEALVMNQKWVPYPAYNDRAGWNELLGTNKESLIRAGEKMLNYE
WKVIRATDYLEYERSGERNIMQNPYEANRKAINALMLAELAEGKGRFIDQLINGAFYSCEMTSWVLSAHLVRQSTKRSLP
DYREQVIDLGSGNFGSMLSWVYYFFHDSFDKIDPVISQRLRHTLQERILDPYMNNDREWWMAFQWKPGMIINNWNPWCNS
NVLQCYLLLENDRDRLAKAVWRSMQSVDKFINFVKADGACEEGPSYWGHAAGKMYDYLQILSDGTDGKVSLFKEPMIRRM
GEYISRTYVGNGWVVNFADASAKGGGDAPLIYRYGRAVGSEEMMQFAAYLLDGKRPSVPLGNDTFRSLQSILWNGELEKT
TAAHTIPACTWYPETEFCYLTNKSGWFLATKGGFNNESHNHNDVGTFSLYVNTIPVLIDAGVGTYTRQTFSSERYTIWTM
QSNYHNLPMINGVPQSFGQNYKATDVVCQPKKRFFSANIATAYPKEAEVNSWTRAYSLGDKQLTITDNFSLKSAKESNQV
NFLTWGKVDISVPGKVTIDVQGQKVTLEYPGEFTATVETINLPDTRLSNVWGTEIYRIALKDKDARLTGKYKFVIK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGSSHHHHHHSSGPQQGLRYTERNLLQKAAGSEEQLKEALVMNQKWVPYPAYNDRAGWNELLGTNKESLIRAGEKMLNYE
WKVIRATDYLEYERSGERNIMQNPYEANRKAINALMLAELAEGKGRFIDQLINGAFYSCEMTSWVLSAHLVRQSTKRSLP
DYREQVIDLGSGNFGSMLSWVYYFFHDSFDKIDPVISQRLRHTLQERILDPYMNNDREWWMAFQWKPGMIINNWNPWCNS
NVLQCYLLLENDRDRLAKAVWRSMQSVDKFINFVKADGACEEGPSYWGHAAGKMYDYLQILSDGTDGKVSLFKEPMIRRM
GEYISRTYVGNGWVVNFADASAKGGGDAPLIYRYGRAVGSEEMMQFAAYLLDGKRPSVPLGNDTFRSLQSILWNGELEKT
TAAHTIPACTWYPETEFCYLTNKSGWFLATKGGFNNESHNHNDVGTFSLYVNTIPVLIDAGVGTYTRQTFSSERYTIWTM
QSNYHNLPMINGVPQSFGQNYKATDVVCQPKKRFFSANIATAYPKEAEVNSWTRAYSLGDKQLTITDNFSLKSAKESNQV
NFLTWGKVDISVPGKVTIDVQGQKVTLEYPGEFTATVETINLPDTRLSNVWGTEIYRIALKDKDARLTGKYKFVIK
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'ZINC ION' ZN  
3 water      HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  SER n 
1 12  SER n 
1 13  GLY n 
1 14  PRO n 
1 15  GLN n 
1 16  GLN n 
1 17  GLY n 
1 18  LEU n 
1 19  ARG n 
1 20  TYR n 
1 21  THR n 
1 22  GLU n 
1 23  ARG n 
1 24  ASN n 
1 25  LEU n 
1 26  LEU n 
1 27  GLN n 
1 28  LYS n 
1 29  ALA n 
1 30  ALA n 
1 31  GLY n 
1 32  SER n 
1 33  GLU n 
1 34  GLU n 
1 35  GLN n 
1 36  LEU n 
1 37  LYS n 
1 38  GLU n 
1 39  ALA n 
1 40  LEU n 
1 41  VAL n 
1 42  MET n 
1 43  ASN n 
1 44  GLN n 
1 45  LYS n 
1 46  TRP n 
1 47  VAL n 
1 48  PRO n 
1 49  TYR n 
1 50  PRO n 
1 51  ALA n 
1 52  TYR n 
1 53  ASN n 
1 54  ASP n 
1 55  ARG n 
1 56  ALA n 
1 57  GLY n 
1 58  TRP n 
1 59  ASN n 
1 60  GLU n 
1 61  LEU n 
1 62  LEU n 
1 63  GLY n 
1 64  THR n 
1 65  ASN n 
1 66  LYS n 
1 67  GLU n 
1 68  SER n 
1 69  LEU n 
1 70  ILE n 
1 71  ARG n 
1 72  ALA n 
1 73  GLY n 
1 74  GLU n 
1 75  LYS n 
1 76  MET n 
1 77  LEU n 
1 78  ASN n 
1 79  TYR n 
1 80  GLU n 
1 81  TRP n 
1 82  LYS n 
1 83  VAL n 
1 84  ILE n 
1 85  ARG n 
1 86  ALA n 
1 87  THR n 
1 88  ASP n 
1 89  TYR n 
1 90  LEU n 
1 91  GLU n 
1 92  TYR n 
1 93  GLU n 
1 94  ARG n 
1 95  SER n 
1 96  GLY n 
1 97  GLU n 
1 98  ARG n 
1 99  ASN n 
1 100 ILE n 
1 101 MET n 
1 102 GLN n 
1 103 ASN n 
1 104 PRO n 
1 105 TYR n 
1 106 GLU n 
1 107 ALA n 
1 108 ASN n 
1 109 ARG n 
1 110 LYS n 
1 111 ALA n 
1 112 ILE n 
1 113 ASN n 
1 114 ALA n 
1 115 LEU n 
1 116 MET n 
1 117 LEU n 
1 118 ALA n 
1 119 GLU n 
1 120 LEU n 
1 121 ALA n 
1 122 GLU n 
1 123 GLY n 
1 124 LYS n 
1 125 GLY n 
1 126 ARG n 
1 127 PHE n 
1 128 ILE n 
1 129 ASP n 
1 130 GLN n 
1 131 LEU n 
1 132 ILE n 
1 133 ASN n 
1 134 GLY n 
1 135 ALA n 
1 136 PHE n 
1 137 TYR n 
1 138 SER n 
1 139 CYS n 
1 140 GLU n 
1 141 MET n 
1 142 THR n 
1 143 SER n 
1 144 TRP n 
1 145 VAL n 
1 146 LEU n 
1 147 SER n 
1 148 ALA n 
1 149 HIS n 
1 150 LEU n 
1 151 VAL n 
1 152 ARG n 
1 153 GLN n 
1 154 SER n 
1 155 THR n 
1 156 LYS n 
1 157 ARG n 
1 158 SER n 
1 159 LEU n 
1 160 PRO n 
1 161 ASP n 
1 162 TYR n 
1 163 ARG n 
1 164 GLU n 
1 165 GLN n 
1 166 VAL n 
1 167 ILE n 
1 168 ASP n 
1 169 LEU n 
1 170 GLY n 
1 171 SER n 
1 172 GLY n 
1 173 ASN n 
1 174 PHE n 
1 175 GLY n 
1 176 SER n 
1 177 MET n 
1 178 LEU n 
1 179 SER n 
1 180 TRP n 
1 181 VAL n 
1 182 TYR n 
1 183 TYR n 
1 184 PHE n 
1 185 PHE n 
1 186 HIS n 
1 187 ASP n 
1 188 SER n 
1 189 PHE n 
1 190 ASP n 
1 191 LYS n 
1 192 ILE n 
1 193 ASP n 
1 194 PRO n 
1 195 VAL n 
1 196 ILE n 
1 197 SER n 
1 198 GLN n 
1 199 ARG n 
1 200 LEU n 
1 201 ARG n 
1 202 HIS n 
1 203 THR n 
1 204 LEU n 
1 205 GLN n 
1 206 GLU n 
1 207 ARG n 
1 208 ILE n 
1 209 LEU n 
1 210 ASP n 
1 211 PRO n 
1 212 TYR n 
1 213 MET n 
1 214 ASN n 
1 215 ASN n 
1 216 ASP n 
1 217 ARG n 
1 218 GLU n 
1 219 TRP n 
1 220 TRP n 
1 221 MET n 
1 222 ALA n 
1 223 PHE n 
1 224 GLN n 
1 225 TRP n 
1 226 LYS n 
1 227 PRO n 
1 228 GLY n 
1 229 MET n 
1 230 ILE n 
1 231 ILE n 
1 232 ASN n 
1 233 ASN n 
1 234 TRP n 
1 235 ASN n 
1 236 PRO n 
1 237 TRP n 
1 238 CYS n 
1 239 ASN n 
1 240 SER n 
1 241 ASN n 
1 242 VAL n 
1 243 LEU n 
1 244 GLN n 
1 245 CYS n 
1 246 TYR n 
1 247 LEU n 
1 248 LEU n 
1 249 LEU n 
1 250 GLU n 
1 251 ASN n 
1 252 ASP n 
1 253 ARG n 
1 254 ASP n 
1 255 ARG n 
1 256 LEU n 
1 257 ALA n 
1 258 LYS n 
1 259 ALA n 
1 260 VAL n 
1 261 TRP n 
1 262 ARG n 
1 263 SER n 
1 264 MET n 
1 265 GLN n 
1 266 SER n 
1 267 VAL n 
1 268 ASP n 
1 269 LYS n 
1 270 PHE n 
1 271 ILE n 
1 272 ASN n 
1 273 PHE n 
1 274 VAL n 
1 275 LYS n 
1 276 ALA n 
1 277 ASP n 
1 278 GLY n 
1 279 ALA n 
1 280 CYS n 
1 281 GLU n 
1 282 GLU n 
1 283 GLY n 
1 284 PRO n 
1 285 SER n 
1 286 TYR n 
1 287 TRP n 
1 288 GLY n 
1 289 HIS n 
1 290 ALA n 
1 291 ALA n 
1 292 GLY n 
1 293 LYS n 
1 294 MET n 
1 295 TYR n 
1 296 ASP n 
1 297 TYR n 
1 298 LEU n 
1 299 GLN n 
1 300 ILE n 
1 301 LEU n 
1 302 SER n 
1 303 ASP n 
1 304 GLY n 
1 305 THR n 
1 306 ASP n 
1 307 GLY n 
1 308 LYS n 
1 309 VAL n 
1 310 SER n 
1 311 LEU n 
1 312 PHE n 
1 313 LYS n 
1 314 GLU n 
1 315 PRO n 
1 316 MET n 
1 317 ILE n 
1 318 ARG n 
1 319 ARG n 
1 320 MET n 
1 321 GLY n 
1 322 GLU n 
1 323 TYR n 
1 324 ILE n 
1 325 SER n 
1 326 ARG n 
1 327 THR n 
1 328 TYR n 
1 329 VAL n 
1 330 GLY n 
1 331 ASN n 
1 332 GLY n 
1 333 TRP n 
1 334 VAL n 
1 335 VAL n 
1 336 ASN n 
1 337 PHE n 
1 338 ALA n 
1 339 ASP n 
1 340 ALA n 
1 341 SER n 
1 342 ALA n 
1 343 LYS n 
1 344 GLY n 
1 345 GLY n 
1 346 GLY n 
1 347 ASP n 
1 348 ALA n 
1 349 PRO n 
1 350 LEU n 
1 351 ILE n 
1 352 TYR n 
1 353 ARG n 
1 354 TYR n 
1 355 GLY n 
1 356 ARG n 
1 357 ALA n 
1 358 VAL n 
1 359 GLY n 
1 360 SER n 
1 361 GLU n 
1 362 GLU n 
1 363 MET n 
1 364 MET n 
1 365 GLN n 
1 366 PHE n 
1 367 ALA n 
1 368 ALA n 
1 369 TYR n 
1 370 LEU n 
1 371 LEU n 
1 372 ASP n 
1 373 GLY n 
1 374 LYS n 
1 375 ARG n 
1 376 PRO n 
1 377 SER n 
1 378 VAL n 
1 379 PRO n 
1 380 LEU n 
1 381 GLY n 
1 382 ASN n 
1 383 ASP n 
1 384 THR n 
1 385 PHE n 
1 386 ARG n 
1 387 SER n 
1 388 LEU n 
1 389 GLN n 
1 390 SER n 
1 391 ILE n 
1 392 LEU n 
1 393 TRP n 
1 394 ASN n 
1 395 GLY n 
1 396 GLU n 
1 397 LEU n 
1 398 GLU n 
1 399 LYS n 
1 400 THR n 
1 401 THR n 
1 402 ALA n 
1 403 ALA n 
1 404 HIS n 
1 405 THR n 
1 406 ILE n 
1 407 PRO n 
1 408 ALA n 
1 409 CYS n 
1 410 THR n 
1 411 TRP n 
1 412 TYR n 
1 413 PRO n 
1 414 GLU n 
1 415 THR n 
1 416 GLU n 
1 417 PHE n 
1 418 CYS n 
1 419 TYR n 
1 420 LEU n 
1 421 THR n 
1 422 ASN n 
1 423 LYS n 
1 424 SER n 
1 425 GLY n 
1 426 TRP n 
1 427 PHE n 
1 428 LEU n 
1 429 ALA n 
1 430 THR n 
1 431 LYS n 
1 432 GLY n 
1 433 GLY n 
1 434 PHE n 
1 435 ASN n 
1 436 ASN n 
1 437 GLU n 
1 438 SER n 
1 439 HIS n 
1 440 ASN n 
1 441 HIS n 
1 442 ASN n 
1 443 ASP n 
1 444 VAL n 
1 445 GLY n 
1 446 THR n 
1 447 PHE n 
1 448 SER n 
1 449 LEU n 
1 450 TYR n 
1 451 VAL n 
1 452 ASN n 
1 453 THR n 
1 454 ILE n 
1 455 PRO n 
1 456 VAL n 
1 457 LEU n 
1 458 ILE n 
1 459 ASP n 
1 460 ALA n 
1 461 GLY n 
1 462 VAL n 
1 463 GLY n 
1 464 THR n 
1 465 TYR n 
1 466 THR n 
1 467 ARG n 
1 468 GLN n 
1 469 THR n 
1 470 PHE n 
1 471 SER n 
1 472 SER n 
1 473 GLU n 
1 474 ARG n 
1 475 TYR n 
1 476 THR n 
1 477 ILE n 
1 478 TRP n 
1 479 THR n 
1 480 MET n 
1 481 GLN n 
1 482 SER n 
1 483 ASN n 
1 484 TYR n 
1 485 HIS n 
1 486 ASN n 
1 487 LEU n 
1 488 PRO n 
1 489 MET n 
1 490 ILE n 
1 491 ASN n 
1 492 GLY n 
1 493 VAL n 
1 494 PRO n 
1 495 GLN n 
1 496 SER n 
1 497 PHE n 
1 498 GLY n 
1 499 GLN n 
1 500 ASN n 
1 501 TYR n 
1 502 LYS n 
1 503 ALA n 
1 504 THR n 
1 505 ASP n 
1 506 VAL n 
1 507 VAL n 
1 508 CYS n 
1 509 GLN n 
1 510 PRO n 
1 511 LYS n 
1 512 LYS n 
1 513 ARG n 
1 514 PHE n 
1 515 PHE n 
1 516 SER n 
1 517 ALA n 
1 518 ASN n 
1 519 ILE n 
1 520 ALA n 
1 521 THR n 
1 522 ALA n 
1 523 TYR n 
1 524 PRO n 
1 525 LYS n 
1 526 GLU n 
1 527 ALA n 
1 528 GLU n 
1 529 VAL n 
1 530 ASN n 
1 531 SER n 
1 532 TRP n 
1 533 THR n 
1 534 ARG n 
1 535 ALA n 
1 536 TYR n 
1 537 SER n 
1 538 LEU n 
1 539 GLY n 
1 540 ASP n 
1 541 LYS n 
1 542 GLN n 
1 543 LEU n 
1 544 THR n 
1 545 ILE n 
1 546 THR n 
1 547 ASP n 
1 548 ASN n 
1 549 PHE n 
1 550 SER n 
1 551 LEU n 
1 552 LYS n 
1 553 SER n 
1 554 ALA n 
1 555 LYS n 
1 556 GLU n 
1 557 SER n 
1 558 ASN n 
1 559 GLN n 
1 560 VAL n 
1 561 ASN n 
1 562 PHE n 
1 563 LEU n 
1 564 THR n 
1 565 TRP n 
1 566 GLY n 
1 567 LYS n 
1 568 VAL n 
1 569 ASP n 
1 570 ILE n 
1 571 SER n 
1 572 VAL n 
1 573 PRO n 
1 574 GLY n 
1 575 LYS n 
1 576 VAL n 
1 577 THR n 
1 578 ILE n 
1 579 ASP n 
1 580 VAL n 
1 581 GLN n 
1 582 GLY n 
1 583 GLN n 
1 584 LYS n 
1 585 VAL n 
1 586 THR n 
1 587 LEU n 
1 588 GLU n 
1 589 TYR n 
1 590 PRO n 
1 591 GLY n 
1 592 GLU n 
1 593 PHE n 
1 594 THR n 
1 595 ALA n 
1 596 THR n 
1 597 VAL n 
1 598 GLU n 
1 599 THR n 
1 600 ILE n 
1 601 ASN n 
1 602 LEU n 
1 603 PRO n 
1 604 ASP n 
1 605 THR n 
1 606 ARG n 
1 607 LEU n 
1 608 SER n 
1 609 ASN n 
1 610 VAL n 
1 611 TRP n 
1 612 GLY n 
1 613 THR n 
1 614 GLU n 
1 615 ILE n 
1 616 TYR n 
1 617 ARG n 
1 618 ILE n 
1 619 ALA n 
1 620 LEU n 
1 621 LYS n 
1 622 ASP n 
1 623 LYS n 
1 624 ASP n 
1 625 ALA n 
1 626 ARG n 
1 627 LEU n 
1 628 THR n 
1 629 GLY n 
1 630 LYS n 
1 631 TYR n 
1 632 LYS n 
1 633 PHE n 
1 634 VAL n 
1 635 ILE n 
1 636 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   636 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 BcellWH2_04512 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Bacteroides cellulosilyticus WH2' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1268240 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
ZN  non-polymer         . 'ZINC ION'      ? 'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   7   ?   ?   ?   A . n 
A 1 2   GLY 2   8   ?   ?   ?   A . n 
A 1 3   SER 3   9   ?   ?   ?   A . n 
A 1 4   SER 4   10  ?   ?   ?   A . n 
A 1 5   HIS 5   11  ?   ?   ?   A . n 
A 1 6   HIS 6   12  ?   ?   ?   A . n 
A 1 7   HIS 7   13  ?   ?   ?   A . n 
A 1 8   HIS 8   14  ?   ?   ?   A . n 
A 1 9   HIS 9   15  ?   ?   ?   A . n 
A 1 10  HIS 10  16  ?   ?   ?   A . n 
A 1 11  SER 11  17  ?   ?   ?   A . n 
A 1 12  SER 12  18  ?   ?   ?   A . n 
A 1 13  GLY 13  19  ?   ?   ?   A . n 
A 1 14  PRO 14  20  ?   ?   ?   A . n 
A 1 15  GLN 15  21  ?   ?   ?   A . n 
A 1 16  GLN 16  22  ?   ?   ?   A . n 
A 1 17  GLY 17  23  ?   ?   ?   A . n 
A 1 18  LEU 18  24  ?   ?   ?   A . n 
A 1 19  ARG 19  25  ?   ?   ?   A . n 
A 1 20  TYR 20  26  26  TYR TYR A . n 
A 1 21  THR 21  27  27  THR THR A . n 
A 1 22  GLU 22  28  28  GLU GLU A . n 
A 1 23  ARG 23  29  29  ARG ARG A . n 
A 1 24  ASN 24  30  30  ASN ASN A . n 
A 1 25  LEU 25  31  31  LEU LEU A . n 
A 1 26  LEU 26  32  32  LEU LEU A . n 
A 1 27  GLN 27  33  33  GLN GLN A . n 
A 1 28  LYS 28  34  34  LYS LYS A . n 
A 1 29  ALA 29  35  35  ALA ALA A . n 
A 1 30  ALA 30  36  36  ALA ALA A . n 
A 1 31  GLY 31  37  37  GLY GLY A . n 
A 1 32  SER 32  38  38  SER SER A . n 
A 1 33  GLU 33  39  39  GLU GLU A . n 
A 1 34  GLU 34  40  40  GLU GLU A . n 
A 1 35  GLN 35  41  41  GLN GLN A . n 
A 1 36  LEU 36  42  42  LEU LEU A . n 
A 1 37  LYS 37  43  43  LYS LYS A . n 
A 1 38  GLU 38  44  44  GLU GLU A . n 
A 1 39  ALA 39  45  45  ALA ALA A . n 
A 1 40  LEU 40  46  46  LEU LEU A . n 
A 1 41  VAL 41  47  47  VAL VAL A . n 
A 1 42  MET 42  48  48  MET MET A . n 
A 1 43  ASN 43  49  49  ASN ASN A . n 
A 1 44  GLN 44  50  50  GLN GLN A . n 
A 1 45  LYS 45  51  51  LYS LYS A . n 
A 1 46  TRP 46  52  52  TRP TRP A . n 
A 1 47  VAL 47  53  53  VAL VAL A . n 
A 1 48  PRO 48  54  54  PRO PRO A . n 
A 1 49  TYR 49  55  55  TYR TYR A . n 
A 1 50  PRO 50  56  56  PRO PRO A . n 
A 1 51  ALA 51  57  57  ALA ALA A . n 
A 1 52  TYR 52  58  58  TYR TYR A . n 
A 1 53  ASN 53  59  59  ASN ASN A . n 
A 1 54  ASP 54  60  60  ASP ASP A . n 
A 1 55  ARG 55  61  61  ARG ARG A . n 
A 1 56  ALA 56  62  62  ALA ALA A . n 
A 1 57  GLY 57  63  63  GLY GLY A . n 
A 1 58  TRP 58  64  64  TRP TRP A . n 
A 1 59  ASN 59  65  65  ASN ASN A . n 
A 1 60  GLU 60  66  66  GLU GLU A . n 
A 1 61  LEU 61  67  67  LEU LEU A . n 
A 1 62  LEU 62  68  68  LEU LEU A . n 
A 1 63  GLY 63  69  69  GLY GLY A . n 
A 1 64  THR 64  70  70  THR THR A . n 
A 1 65  ASN 65  71  71  ASN ASN A . n 
A 1 66  LYS 66  72  72  LYS LYS A . n 
A 1 67  GLU 67  73  73  GLU GLU A . n 
A 1 68  SER 68  74  74  SER SER A . n 
A 1 69  LEU 69  75  75  LEU LEU A . n 
A 1 70  ILE 70  76  76  ILE ILE A . n 
A 1 71  ARG 71  77  77  ARG ARG A . n 
A 1 72  ALA 72  78  78  ALA ALA A . n 
A 1 73  GLY 73  79  79  GLY GLY A . n 
A 1 74  GLU 74  80  80  GLU GLU A . n 
A 1 75  LYS 75  81  81  LYS LYS A . n 
A 1 76  MET 76  82  82  MET MET A . n 
A 1 77  LEU 77  83  83  LEU LEU A . n 
A 1 78  ASN 78  84  84  ASN ASN A . n 
A 1 79  TYR 79  85  85  TYR TYR A . n 
A 1 80  GLU 80  86  86  GLU GLU A . n 
A 1 81  TRP 81  87  87  TRP TRP A . n 
A 1 82  LYS 82  88  88  LYS LYS A . n 
A 1 83  VAL 83  89  89  VAL VAL A . n 
A 1 84  ILE 84  90  90  ILE ILE A . n 
A 1 85  ARG 85  91  91  ARG ARG A . n 
A 1 86  ALA 86  92  92  ALA ALA A . n 
A 1 87  THR 87  93  93  THR THR A . n 
A 1 88  ASP 88  94  94  ASP ASP A . n 
A 1 89  TYR 89  95  95  TYR TYR A . n 
A 1 90  LEU 90  96  96  LEU LEU A . n 
A 1 91  GLU 91  97  97  GLU GLU A . n 
A 1 92  TYR 92  98  98  TYR TYR A . n 
A 1 93  GLU 93  99  99  GLU GLU A . n 
A 1 94  ARG 94  100 100 ARG ARG A . n 
A 1 95  SER 95  101 101 SER SER A . n 
A 1 96  GLY 96  102 102 GLY GLY A . n 
A 1 97  GLU 97  103 103 GLU GLU A . n 
A 1 98  ARG 98  104 104 ARG ARG A . n 
A 1 99  ASN 99  105 105 ASN ASN A . n 
A 1 100 ILE 100 106 106 ILE ILE A . n 
A 1 101 MET 101 107 107 MET MET A . n 
A 1 102 GLN 102 108 108 GLN GLN A . n 
A 1 103 ASN 103 109 109 ASN ASN A . n 
A 1 104 PRO 104 110 110 PRO PRO A . n 
A 1 105 TYR 105 111 111 TYR TYR A . n 
A 1 106 GLU 106 112 112 GLU GLU A . n 
A 1 107 ALA 107 113 113 ALA ALA A . n 
A 1 108 ASN 108 114 114 ASN ASN A . n 
A 1 109 ARG 109 115 115 ARG ARG A . n 
A 1 110 LYS 110 116 116 LYS LYS A . n 
A 1 111 ALA 111 117 117 ALA ALA A . n 
A 1 112 ILE 112 118 118 ILE ILE A . n 
A 1 113 ASN 113 119 119 ASN ASN A . n 
A 1 114 ALA 114 120 120 ALA ALA A . n 
A 1 115 LEU 115 121 121 LEU LEU A . n 
A 1 116 MET 116 122 122 MET MET A . n 
A 1 117 LEU 117 123 123 LEU LEU A . n 
A 1 118 ALA 118 124 124 ALA ALA A . n 
A 1 119 GLU 119 125 125 GLU GLU A . n 
A 1 120 LEU 120 126 126 LEU LEU A . n 
A 1 121 ALA 121 127 127 ALA ALA A . n 
A 1 122 GLU 122 128 128 GLU GLU A . n 
A 1 123 GLY 123 129 129 GLY GLY A . n 
A 1 124 LYS 124 130 130 LYS LYS A . n 
A 1 125 GLY 125 131 131 GLY GLY A . n 
A 1 126 ARG 126 132 132 ARG ARG A . n 
A 1 127 PHE 127 133 133 PHE PHE A . n 
A 1 128 ILE 128 134 134 ILE ILE A . n 
A 1 129 ASP 129 135 135 ASP ASP A . n 
A 1 130 GLN 130 136 136 GLN GLN A . n 
A 1 131 LEU 131 137 137 LEU LEU A . n 
A 1 132 ILE 132 138 138 ILE ILE A . n 
A 1 133 ASN 133 139 139 ASN ASN A . n 
A 1 134 GLY 134 140 140 GLY GLY A . n 
A 1 135 ALA 135 141 141 ALA ALA A . n 
A 1 136 PHE 136 142 142 PHE PHE A . n 
A 1 137 TYR 137 143 143 TYR TYR A . n 
A 1 138 SER 138 144 144 SER SER A . n 
A 1 139 CYS 139 145 145 CYS CYS A . n 
A 1 140 GLU 140 146 146 GLU GLU A . n 
A 1 141 MET 141 147 147 MET MET A . n 
A 1 142 THR 142 148 148 THR THR A . n 
A 1 143 SER 143 149 149 SER SER A . n 
A 1 144 TRP 144 150 150 TRP TRP A . n 
A 1 145 VAL 145 151 151 VAL VAL A . n 
A 1 146 LEU 146 152 152 LEU LEU A . n 
A 1 147 SER 147 153 153 SER SER A . n 
A 1 148 ALA 148 154 154 ALA ALA A . n 
A 1 149 HIS 149 155 155 HIS HIS A . n 
A 1 150 LEU 150 156 156 LEU LEU A . n 
A 1 151 VAL 151 157 157 VAL VAL A . n 
A 1 152 ARG 152 158 158 ARG ARG A . n 
A 1 153 GLN 153 159 159 GLN GLN A . n 
A 1 154 SER 154 160 160 SER SER A . n 
A 1 155 THR 155 161 161 THR THR A . n 
A 1 156 LYS 156 162 162 LYS LYS A . n 
A 1 157 ARG 157 163 163 ARG ARG A . n 
A 1 158 SER 158 164 164 SER SER A . n 
A 1 159 LEU 159 165 165 LEU LEU A . n 
A 1 160 PRO 160 166 166 PRO PRO A . n 
A 1 161 ASP 161 167 167 ASP ASP A . n 
A 1 162 TYR 162 168 168 TYR TYR A . n 
A 1 163 ARG 163 169 169 ARG ARG A . n 
A 1 164 GLU 164 170 170 GLU GLU A . n 
A 1 165 GLN 165 171 171 GLN GLN A . n 
A 1 166 VAL 166 172 172 VAL VAL A . n 
A 1 167 ILE 167 173 173 ILE ILE A . n 
A 1 168 ASP 168 174 174 ASP ASP A . n 
A 1 169 LEU 169 175 175 LEU LEU A . n 
A 1 170 GLY 170 176 176 GLY GLY A . n 
A 1 171 SER 171 177 177 SER SER A . n 
A 1 172 GLY 172 178 178 GLY GLY A . n 
A 1 173 ASN 173 179 179 ASN ASN A . n 
A 1 174 PHE 174 180 180 PHE PHE A . n 
A 1 175 GLY 175 181 181 GLY GLY A . n 
A 1 176 SER 176 182 182 SER SER A . n 
A 1 177 MET 177 183 183 MET MET A . n 
A 1 178 LEU 178 184 184 LEU LEU A . n 
A 1 179 SER 179 185 185 SER SER A . n 
A 1 180 TRP 180 186 186 TRP TRP A . n 
A 1 181 VAL 181 187 187 VAL VAL A . n 
A 1 182 TYR 182 188 188 TYR TYR A . n 
A 1 183 TYR 183 189 189 TYR TYR A . n 
A 1 184 PHE 184 190 190 PHE PHE A . n 
A 1 185 PHE 185 191 191 PHE PHE A . n 
A 1 186 HIS 186 192 192 HIS HIS A . n 
A 1 187 ASP 187 193 193 ASP ASP A . n 
A 1 188 SER 188 194 194 SER SER A . n 
A 1 189 PHE 189 195 195 PHE PHE A . n 
A 1 190 ASP 190 196 196 ASP ASP A . n 
A 1 191 LYS 191 197 197 LYS LYS A . n 
A 1 192 ILE 192 198 198 ILE ILE A . n 
A 1 193 ASP 193 199 199 ASP ASP A . n 
A 1 194 PRO 194 200 200 PRO PRO A . n 
A 1 195 VAL 195 201 201 VAL VAL A . n 
A 1 196 ILE 196 202 202 ILE ILE A . n 
A 1 197 SER 197 203 203 SER SER A . n 
A 1 198 GLN 198 204 204 GLN GLN A . n 
A 1 199 ARG 199 205 205 ARG ARG A . n 
A 1 200 LEU 200 206 206 LEU LEU A . n 
A 1 201 ARG 201 207 207 ARG ARG A . n 
A 1 202 HIS 202 208 208 HIS HIS A . n 
A 1 203 THR 203 209 209 THR THR A . n 
A 1 204 LEU 204 210 210 LEU LEU A . n 
A 1 205 GLN 205 211 211 GLN GLN A . n 
A 1 206 GLU 206 212 212 GLU GLU A . n 
A 1 207 ARG 207 213 213 ARG ARG A . n 
A 1 208 ILE 208 214 214 ILE ILE A . n 
A 1 209 LEU 209 215 215 LEU LEU A . n 
A 1 210 ASP 210 216 216 ASP ASP A . n 
A 1 211 PRO 211 217 217 PRO PRO A . n 
A 1 212 TYR 212 218 218 TYR TYR A . n 
A 1 213 MET 213 219 219 MET MET A . n 
A 1 214 ASN 214 220 220 ASN ASN A . n 
A 1 215 ASN 215 221 221 ASN ASN A . n 
A 1 216 ASP 216 222 222 ASP ASP A . n 
A 1 217 ARG 217 223 223 ARG ARG A . n 
A 1 218 GLU 218 224 224 GLU GLU A . n 
A 1 219 TRP 219 225 225 TRP TRP A . n 
A 1 220 TRP 220 226 226 TRP TRP A . n 
A 1 221 MET 221 227 227 MET MET A . n 
A 1 222 ALA 222 228 228 ALA ALA A . n 
A 1 223 PHE 223 229 229 PHE PHE A . n 
A 1 224 GLN 224 230 230 GLN GLN A . n 
A 1 225 TRP 225 231 231 TRP TRP A . n 
A 1 226 LYS 226 232 232 LYS LYS A . n 
A 1 227 PRO 227 233 233 PRO PRO A . n 
A 1 228 GLY 228 234 234 GLY GLY A . n 
A 1 229 MET 229 235 235 MET MET A . n 
A 1 230 ILE 230 236 236 ILE ILE A . n 
A 1 231 ILE 231 237 237 ILE ILE A . n 
A 1 232 ASN 232 238 238 ASN ASN A . n 
A 1 233 ASN 233 239 239 ASN ASN A . n 
A 1 234 TRP 234 240 240 TRP TRP A . n 
A 1 235 ASN 235 241 241 ASN ASN A . n 
A 1 236 PRO 236 242 242 PRO PRO A . n 
A 1 237 TRP 237 243 243 TRP TRP A . n 
A 1 238 CYS 238 244 244 CYS CYS A . n 
A 1 239 ASN 239 245 245 ASN ASN A . n 
A 1 240 SER 240 246 246 SER SER A . n 
A 1 241 ASN 241 247 247 ASN ASN A . n 
A 1 242 VAL 242 248 248 VAL VAL A . n 
A 1 243 LEU 243 249 249 LEU LEU A . n 
A 1 244 GLN 244 250 250 GLN GLN A . n 
A 1 245 CYS 245 251 251 CYS CYS A . n 
A 1 246 TYR 246 252 252 TYR TYR A . n 
A 1 247 LEU 247 253 253 LEU LEU A . n 
A 1 248 LEU 248 254 254 LEU LEU A . n 
A 1 249 LEU 249 255 255 LEU LEU A . n 
A 1 250 GLU 250 256 256 GLU GLU A . n 
A 1 251 ASN 251 257 257 ASN ASN A . n 
A 1 252 ASP 252 258 258 ASP ASP A . n 
A 1 253 ARG 253 259 259 ARG ARG A . n 
A 1 254 ASP 254 260 260 ASP ASP A . n 
A 1 255 ARG 255 261 261 ARG ARG A . n 
A 1 256 LEU 256 262 262 LEU LEU A . n 
A 1 257 ALA 257 263 263 ALA ALA A . n 
A 1 258 LYS 258 264 264 LYS LYS A . n 
A 1 259 ALA 259 265 265 ALA ALA A . n 
A 1 260 VAL 260 266 266 VAL VAL A . n 
A 1 261 TRP 261 267 267 TRP TRP A . n 
A 1 262 ARG 262 268 268 ARG ARG A . n 
A 1 263 SER 263 269 269 SER SER A . n 
A 1 264 MET 264 270 270 MET MET A . n 
A 1 265 GLN 265 271 271 GLN GLN A . n 
A 1 266 SER 266 272 272 SER SER A . n 
A 1 267 VAL 267 273 273 VAL VAL A . n 
A 1 268 ASP 268 274 274 ASP ASP A . n 
A 1 269 LYS 269 275 275 LYS LYS A . n 
A 1 270 PHE 270 276 276 PHE PHE A . n 
A 1 271 ILE 271 277 277 ILE ILE A . n 
A 1 272 ASN 272 278 278 ASN ASN A . n 
A 1 273 PHE 273 279 279 PHE PHE A . n 
A 1 274 VAL 274 280 280 VAL VAL A . n 
A 1 275 LYS 275 281 281 LYS LYS A . n 
A 1 276 ALA 276 282 282 ALA ALA A . n 
A 1 277 ASP 277 283 283 ASP ASP A . n 
A 1 278 GLY 278 284 284 GLY GLY A . n 
A 1 279 ALA 279 285 285 ALA ALA A . n 
A 1 280 CYS 280 286 286 CYS CYS A . n 
A 1 281 GLU 281 287 287 GLU GLU A . n 
A 1 282 GLU 282 288 288 GLU GLU A . n 
A 1 283 GLY 283 289 289 GLY GLY A . n 
A 1 284 PRO 284 290 290 PRO PRO A . n 
A 1 285 SER 285 291 291 SER SER A . n 
A 1 286 TYR 286 292 292 TYR TYR A . n 
A 1 287 TRP 287 293 293 TRP TRP A . n 
A 1 288 GLY 288 294 294 GLY GLY A . n 
A 1 289 HIS 289 295 295 HIS HIS A . n 
A 1 290 ALA 290 296 296 ALA ALA A . n 
A 1 291 ALA 291 297 297 ALA ALA A . n 
A 1 292 GLY 292 298 298 GLY GLY A . n 
A 1 293 LYS 293 299 299 LYS LYS A . n 
A 1 294 MET 294 300 300 MET MET A . n 
A 1 295 TYR 295 301 301 TYR TYR A . n 
A 1 296 ASP 296 302 302 ASP ASP A . n 
A 1 297 TYR 297 303 303 TYR TYR A . n 
A 1 298 LEU 298 304 304 LEU LEU A . n 
A 1 299 GLN 299 305 305 GLN GLN A . n 
A 1 300 ILE 300 306 306 ILE ILE A . n 
A 1 301 LEU 301 307 307 LEU LEU A . n 
A 1 302 SER 302 308 308 SER SER A . n 
A 1 303 ASP 303 309 309 ASP ASP A . n 
A 1 304 GLY 304 310 310 GLY GLY A . n 
A 1 305 THR 305 311 311 THR THR A . n 
A 1 306 ASP 306 312 312 ASP ASP A . n 
A 1 307 GLY 307 313 313 GLY GLY A . n 
A 1 308 LYS 308 314 314 LYS LYS A . n 
A 1 309 VAL 309 315 315 VAL VAL A . n 
A 1 310 SER 310 316 316 SER SER A . n 
A 1 311 LEU 311 317 317 LEU LEU A . n 
A 1 312 PHE 312 318 318 PHE PHE A . n 
A 1 313 LYS 313 319 319 LYS LYS A . n 
A 1 314 GLU 314 320 320 GLU GLU A . n 
A 1 315 PRO 315 321 321 PRO PRO A . n 
A 1 316 MET 316 322 322 MET MET A . n 
A 1 317 ILE 317 323 323 ILE ILE A . n 
A 1 318 ARG 318 324 324 ARG ARG A . n 
A 1 319 ARG 319 325 325 ARG ARG A . n 
A 1 320 MET 320 326 326 MET MET A . n 
A 1 321 GLY 321 327 327 GLY GLY A . n 
A 1 322 GLU 322 328 328 GLU GLU A . n 
A 1 323 TYR 323 329 329 TYR TYR A . n 
A 1 324 ILE 324 330 330 ILE ILE A . n 
A 1 325 SER 325 331 331 SER SER A . n 
A 1 326 ARG 326 332 332 ARG ARG A . n 
A 1 327 THR 327 333 333 THR THR A . n 
A 1 328 TYR 328 334 334 TYR TYR A . n 
A 1 329 VAL 329 335 335 VAL VAL A . n 
A 1 330 GLY 330 336 336 GLY GLY A . n 
A 1 331 ASN 331 337 337 ASN ASN A . n 
A 1 332 GLY 332 338 338 GLY GLY A . n 
A 1 333 TRP 333 339 339 TRP TRP A . n 
A 1 334 VAL 334 340 340 VAL VAL A . n 
A 1 335 VAL 335 341 341 VAL VAL A . n 
A 1 336 ASN 336 342 342 ASN ASN A . n 
A 1 337 PHE 337 343 343 PHE PHE A . n 
A 1 338 ALA 338 344 344 ALA ALA A . n 
A 1 339 ASP 339 345 345 ASP ASP A . n 
A 1 340 ALA 340 346 346 ALA ALA A . n 
A 1 341 SER 341 347 347 SER SER A . n 
A 1 342 ALA 342 348 348 ALA ALA A . n 
A 1 343 LYS 343 349 349 LYS LYS A . n 
A 1 344 GLY 344 350 350 GLY GLY A . n 
A 1 345 GLY 345 351 351 GLY GLY A . n 
A 1 346 GLY 346 352 352 GLY GLY A . n 
A 1 347 ASP 347 353 353 ASP ASP A . n 
A 1 348 ALA 348 354 354 ALA ALA A . n 
A 1 349 PRO 349 355 355 PRO PRO A . n 
A 1 350 LEU 350 356 356 LEU LEU A . n 
A 1 351 ILE 351 357 357 ILE ILE A . n 
A 1 352 TYR 352 358 358 TYR TYR A . n 
A 1 353 ARG 353 359 359 ARG ARG A . n 
A 1 354 TYR 354 360 360 TYR TYR A . n 
A 1 355 GLY 355 361 361 GLY GLY A . n 
A 1 356 ARG 356 362 362 ARG ARG A . n 
A 1 357 ALA 357 363 363 ALA ALA A . n 
A 1 358 VAL 358 364 364 VAL VAL A . n 
A 1 359 GLY 359 365 365 GLY GLY A . n 
A 1 360 SER 360 366 366 SER SER A . n 
A 1 361 GLU 361 367 367 GLU GLU A . n 
A 1 362 GLU 362 368 368 GLU GLU A . n 
A 1 363 MET 363 369 369 MET MET A . n 
A 1 364 MET 364 370 370 MET MET A . n 
A 1 365 GLN 365 371 371 GLN GLN A . n 
A 1 366 PHE 366 372 372 PHE PHE A . n 
A 1 367 ALA 367 373 373 ALA ALA A . n 
A 1 368 ALA 368 374 374 ALA ALA A . n 
A 1 369 TYR 369 375 375 TYR TYR A . n 
A 1 370 LEU 370 376 376 LEU LEU A . n 
A 1 371 LEU 371 377 377 LEU LEU A . n 
A 1 372 ASP 372 378 378 ASP ASP A . n 
A 1 373 GLY 373 379 379 GLY GLY A . n 
A 1 374 LYS 374 380 380 LYS LYS A . n 
A 1 375 ARG 375 381 381 ARG ARG A . n 
A 1 376 PRO 376 382 382 PRO PRO A . n 
A 1 377 SER 377 383 383 SER SER A . n 
A 1 378 VAL 378 384 384 VAL VAL A . n 
A 1 379 PRO 379 385 385 PRO PRO A . n 
A 1 380 LEU 380 386 386 LEU LEU A . n 
A 1 381 GLY 381 387 387 GLY GLY A . n 
A 1 382 ASN 382 388 388 ASN ASN A . n 
A 1 383 ASP 383 389 389 ASP ASP A . n 
A 1 384 THR 384 390 390 THR THR A . n 
A 1 385 PHE 385 391 391 PHE PHE A . n 
A 1 386 ARG 386 392 392 ARG ARG A . n 
A 1 387 SER 387 393 393 SER SER A . n 
A 1 388 LEU 388 394 394 LEU LEU A . n 
A 1 389 GLN 389 395 395 GLN GLN A . n 
A 1 390 SER 390 396 396 SER SER A . n 
A 1 391 ILE 391 397 397 ILE ILE A . n 
A 1 392 LEU 392 398 398 LEU LEU A . n 
A 1 393 TRP 393 399 399 TRP TRP A . n 
A 1 394 ASN 394 400 400 ASN ASN A . n 
A 1 395 GLY 395 401 401 GLY GLY A . n 
A 1 396 GLU 396 402 402 GLU GLU A . n 
A 1 397 LEU 397 403 403 LEU LEU A . n 
A 1 398 GLU 398 404 404 GLU GLU A . n 
A 1 399 LYS 399 405 405 LYS LYS A . n 
A 1 400 THR 400 406 406 THR THR A . n 
A 1 401 THR 401 407 407 THR THR A . n 
A 1 402 ALA 402 408 408 ALA ALA A . n 
A 1 403 ALA 403 409 409 ALA ALA A . n 
A 1 404 HIS 404 410 410 HIS HIS A . n 
A 1 405 THR 405 411 411 THR THR A . n 
A 1 406 ILE 406 412 412 ILE ILE A . n 
A 1 407 PRO 407 413 413 PRO PRO A . n 
A 1 408 ALA 408 414 414 ALA ALA A . n 
A 1 409 CYS 409 415 415 CYS CYS A . n 
A 1 410 THR 410 416 416 THR THR A . n 
A 1 411 TRP 411 417 417 TRP TRP A . n 
A 1 412 TYR 412 418 418 TYR TYR A . n 
A 1 413 PRO 413 419 419 PRO PRO A . n 
A 1 414 GLU 414 420 420 GLU GLU A . n 
A 1 415 THR 415 421 421 THR THR A . n 
A 1 416 GLU 416 422 422 GLU GLU A . n 
A 1 417 PHE 417 423 423 PHE PHE A . n 
A 1 418 CYS 418 424 424 CYS CYS A . n 
A 1 419 TYR 419 425 425 TYR TYR A . n 
A 1 420 LEU 420 426 426 LEU LEU A . n 
A 1 421 THR 421 427 427 THR THR A . n 
A 1 422 ASN 422 428 428 ASN ASN A . n 
A 1 423 LYS 423 429 429 LYS LYS A . n 
A 1 424 SER 424 430 430 SER SER A . n 
A 1 425 GLY 425 431 431 GLY GLY A . n 
A 1 426 TRP 426 432 432 TRP TRP A . n 
A 1 427 PHE 427 433 433 PHE PHE A . n 
A 1 428 LEU 428 434 434 LEU LEU A . n 
A 1 429 ALA 429 435 435 ALA ALA A . n 
A 1 430 THR 430 436 436 THR THR A . n 
A 1 431 LYS 431 437 437 LYS LYS A . n 
A 1 432 GLY 432 438 438 GLY GLY A . n 
A 1 433 GLY 433 439 439 GLY GLY A . n 
A 1 434 PHE 434 440 440 PHE PHE A . n 
A 1 435 ASN 435 441 441 ASN ASN A . n 
A 1 436 ASN 436 442 442 ASN ASN A . n 
A 1 437 GLU 437 443 443 GLU GLU A . n 
A 1 438 SER 438 444 444 SER SER A . n 
A 1 439 HIS 439 445 445 HIS HIS A . n 
A 1 440 ASN 440 446 446 ASN ASN A . n 
A 1 441 HIS 441 447 447 HIS HIS A . n 
A 1 442 ASN 442 448 448 ASN ASN A . n 
A 1 443 ASP 443 449 449 ASP ASP A . n 
A 1 444 VAL 444 450 450 VAL VAL A . n 
A 1 445 GLY 445 451 451 GLY GLY A . n 
A 1 446 THR 446 452 452 THR THR A . n 
A 1 447 PHE 447 453 453 PHE PHE A . n 
A 1 448 SER 448 454 454 SER SER A . n 
A 1 449 LEU 449 455 455 LEU LEU A . n 
A 1 450 TYR 450 456 456 TYR TYR A . n 
A 1 451 VAL 451 457 457 VAL VAL A . n 
A 1 452 ASN 452 458 458 ASN ASN A . n 
A 1 453 THR 453 459 459 THR THR A . n 
A 1 454 ILE 454 460 460 ILE ILE A . n 
A 1 455 PRO 455 461 461 PRO PRO A . n 
A 1 456 VAL 456 462 462 VAL VAL A . n 
A 1 457 LEU 457 463 463 LEU LEU A . n 
A 1 458 ILE 458 464 464 ILE ILE A . n 
A 1 459 ASP 459 465 465 ASP ASP A . n 
A 1 460 ALA 460 466 466 ALA ALA A . n 
A 1 461 GLY 461 467 467 GLY GLY A . n 
A 1 462 VAL 462 468 468 VAL VAL A . n 
A 1 463 GLY 463 469 469 GLY GLY A . n 
A 1 464 THR 464 470 470 THR THR A . n 
A 1 465 TYR 465 471 471 TYR TYR A . n 
A 1 466 THR 466 472 472 THR THR A . n 
A 1 467 ARG 467 473 473 ARG ARG A . n 
A 1 468 GLN 468 474 474 GLN GLN A . n 
A 1 469 THR 469 475 475 THR THR A . n 
A 1 470 PHE 470 476 476 PHE PHE A . n 
A 1 471 SER 471 477 477 SER SER A . n 
A 1 472 SER 472 478 478 SER SER A . n 
A 1 473 GLU 473 479 479 GLU GLU A . n 
A 1 474 ARG 474 480 480 ARG ARG A . n 
A 1 475 TYR 475 481 481 TYR TYR A . n 
A 1 476 THR 476 482 482 THR THR A . n 
A 1 477 ILE 477 483 483 ILE ILE A . n 
A 1 478 TRP 478 484 484 TRP TRP A . n 
A 1 479 THR 479 485 485 THR THR A . n 
A 1 480 MET 480 486 486 MET MET A . n 
A 1 481 GLN 481 487 487 GLN GLN A . n 
A 1 482 SER 482 488 488 SER SER A . n 
A 1 483 ASN 483 489 489 ASN ASN A . n 
A 1 484 TYR 484 490 490 TYR TYR A . n 
A 1 485 HIS 485 491 491 HIS HIS A . n 
A 1 486 ASN 486 492 492 ASN ASN A . n 
A 1 487 LEU 487 493 493 LEU LEU A . n 
A 1 488 PRO 488 494 494 PRO PRO A . n 
A 1 489 MET 489 495 495 MET MET A . n 
A 1 490 ILE 490 496 496 ILE ILE A . n 
A 1 491 ASN 491 497 497 ASN ASN A . n 
A 1 492 GLY 492 498 498 GLY GLY A . n 
A 1 493 VAL 493 499 499 VAL VAL A . n 
A 1 494 PRO 494 500 500 PRO PRO A . n 
A 1 495 GLN 495 501 501 GLN GLN A . n 
A 1 496 SER 496 502 502 SER SER A . n 
A 1 497 PHE 497 503 503 PHE PHE A . n 
A 1 498 GLY 498 504 504 GLY GLY A . n 
A 1 499 GLN 499 505 505 GLN GLN A . n 
A 1 500 ASN 500 506 506 ASN ASN A . n 
A 1 501 TYR 501 507 507 TYR TYR A . n 
A 1 502 LYS 502 508 508 LYS LYS A . n 
A 1 503 ALA 503 509 509 ALA ALA A . n 
A 1 504 THR 504 510 510 THR THR A . n 
A 1 505 ASP 505 511 511 ASP ASP A . n 
A 1 506 VAL 506 512 512 VAL VAL A . n 
A 1 507 VAL 507 513 513 VAL VAL A . n 
A 1 508 CYS 508 514 514 CYS CYS A . n 
A 1 509 GLN 509 515 515 GLN GLN A . n 
A 1 510 PRO 510 516 516 PRO PRO A . n 
A 1 511 LYS 511 517 517 LYS LYS A . n 
A 1 512 LYS 512 518 518 LYS LYS A . n 
A 1 513 ARG 513 519 519 ARG ARG A . n 
A 1 514 PHE 514 520 520 PHE PHE A . n 
A 1 515 PHE 515 521 521 PHE PHE A . n 
A 1 516 SER 516 522 522 SER SER A . n 
A 1 517 ALA 517 523 523 ALA ALA A . n 
A 1 518 ASN 518 524 524 ASN ASN A . n 
A 1 519 ILE 519 525 525 ILE ILE A . n 
A 1 520 ALA 520 526 526 ALA ALA A . n 
A 1 521 THR 521 527 527 THR THR A . n 
A 1 522 ALA 522 528 528 ALA ALA A . n 
A 1 523 TYR 523 529 529 TYR TYR A . n 
A 1 524 PRO 524 530 530 PRO PRO A . n 
A 1 525 LYS 525 531 531 LYS LYS A . n 
A 1 526 GLU 526 532 532 GLU GLU A . n 
A 1 527 ALA 527 533 533 ALA ALA A . n 
A 1 528 GLU 528 534 534 GLU GLU A . n 
A 1 529 VAL 529 535 535 VAL VAL A . n 
A 1 530 ASN 530 536 536 ASN ASN A . n 
A 1 531 SER 531 537 537 SER SER A . n 
A 1 532 TRP 532 538 538 TRP TRP A . n 
A 1 533 THR 533 539 539 THR THR A . n 
A 1 534 ARG 534 540 540 ARG ARG A . n 
A 1 535 ALA 535 541 541 ALA ALA A . n 
A 1 536 TYR 536 542 542 TYR TYR A . n 
A 1 537 SER 537 543 543 SER SER A . n 
A 1 538 LEU 538 544 544 LEU LEU A . n 
A 1 539 GLY 539 545 545 GLY GLY A . n 
A 1 540 ASP 540 546 546 ASP ASP A . n 
A 1 541 LYS 541 547 547 LYS LYS A . n 
A 1 542 GLN 542 548 548 GLN GLN A . n 
A 1 543 LEU 543 549 549 LEU LEU A . n 
A 1 544 THR 544 550 550 THR THR A . n 
A 1 545 ILE 545 551 551 ILE ILE A . n 
A 1 546 THR 546 552 552 THR THR A . n 
A 1 547 ASP 547 553 553 ASP ASP A . n 
A 1 548 ASN 548 554 554 ASN ASN A . n 
A 1 549 PHE 549 555 555 PHE PHE A . n 
A 1 550 SER 550 556 556 SER SER A . n 
A 1 551 LEU 551 557 557 LEU LEU A . n 
A 1 552 LYS 552 558 558 LYS LYS A . n 
A 1 553 SER 553 559 559 SER SER A . n 
A 1 554 ALA 554 560 560 ALA ALA A . n 
A 1 555 LYS 555 561 561 LYS LYS A . n 
A 1 556 GLU 556 562 562 GLU GLU A . n 
A 1 557 SER 557 563 563 SER SER A . n 
A 1 558 ASN 558 564 564 ASN ASN A . n 
A 1 559 GLN 559 565 565 GLN GLN A . n 
A 1 560 VAL 560 566 566 VAL VAL A . n 
A 1 561 ASN 561 567 567 ASN ASN A . n 
A 1 562 PHE 562 568 568 PHE PHE A . n 
A 1 563 LEU 563 569 569 LEU LEU A . n 
A 1 564 THR 564 570 570 THR THR A . n 
A 1 565 TRP 565 571 571 TRP TRP A . n 
A 1 566 GLY 566 572 572 GLY GLY A . n 
A 1 567 LYS 567 573 573 LYS LYS A . n 
A 1 568 VAL 568 574 574 VAL VAL A . n 
A 1 569 ASP 569 575 575 ASP ASP A . n 
A 1 570 ILE 570 576 576 ILE ILE A . n 
A 1 571 SER 571 577 577 SER SER A . n 
A 1 572 VAL 572 578 578 VAL VAL A . n 
A 1 573 PRO 573 579 579 PRO PRO A . n 
A 1 574 GLY 574 580 580 GLY GLY A . n 
A 1 575 LYS 575 581 581 LYS LYS A . n 
A 1 576 VAL 576 582 582 VAL VAL A . n 
A 1 577 THR 577 583 583 THR THR A . n 
A 1 578 ILE 578 584 584 ILE ILE A . n 
A 1 579 ASP 579 585 585 ASP ASP A . n 
A 1 580 VAL 580 586 586 VAL VAL A . n 
A 1 581 GLN 581 587 587 GLN GLN A . n 
A 1 582 GLY 582 588 588 GLY GLY A . n 
A 1 583 GLN 583 589 589 GLN GLN A . n 
A 1 584 LYS 584 590 590 LYS LYS A . n 
A 1 585 VAL 585 591 591 VAL VAL A . n 
A 1 586 THR 586 592 592 THR THR A . n 
A 1 587 LEU 587 593 593 LEU LEU A . n 
A 1 588 GLU 588 594 594 GLU GLU A . n 
A 1 589 TYR 589 595 595 TYR TYR A . n 
A 1 590 PRO 590 596 596 PRO PRO A . n 
A 1 591 GLY 591 597 597 GLY GLY A . n 
A 1 592 GLU 592 598 598 GLU GLU A . n 
A 1 593 PHE 593 599 599 PHE PHE A . n 
A 1 594 THR 594 600 600 THR THR A . n 
A 1 595 ALA 595 601 601 ALA ALA A . n 
A 1 596 THR 596 602 602 THR THR A . n 
A 1 597 VAL 597 603 603 VAL VAL A . n 
A 1 598 GLU 598 604 604 GLU GLU A . n 
A 1 599 THR 599 605 605 THR THR A . n 
A 1 600 ILE 600 606 606 ILE ILE A . n 
A 1 601 ASN 601 607 607 ASN ASN A . n 
A 1 602 LEU 602 608 608 LEU LEU A . n 
A 1 603 PRO 603 609 609 PRO PRO A . n 
A 1 604 ASP 604 610 610 ASP ASP A . n 
A 1 605 THR 605 611 611 THR THR A . n 
A 1 606 ARG 606 612 612 ARG ARG A . n 
A 1 607 LEU 607 613 613 LEU LEU A . n 
A 1 608 SER 608 614 614 SER SER A . n 
A 1 609 ASN 609 615 615 ASN ASN A . n 
A 1 610 VAL 610 616 616 VAL VAL A . n 
A 1 611 TRP 611 617 617 TRP TRP A . n 
A 1 612 GLY 612 618 618 GLY GLY A . n 
A 1 613 THR 613 619 619 THR THR A . n 
A 1 614 GLU 614 620 620 GLU GLU A . n 
A 1 615 ILE 615 621 621 ILE ILE A . n 
A 1 616 TYR 616 622 622 TYR TYR A . n 
A 1 617 ARG 617 623 623 ARG ARG A . n 
A 1 618 ILE 618 624 624 ILE ILE A . n 
A 1 619 ALA 619 625 625 ALA ALA A . n 
A 1 620 LEU 620 626 626 LEU LEU A . n 
A 1 621 LYS 621 627 627 LYS LYS A . n 
A 1 622 ASP 622 628 628 ASP ASP A . n 
A 1 623 LYS 623 629 629 LYS LYS A . n 
A 1 624 ASP 624 630 630 ASP ASP A . n 
A 1 625 ALA 625 631 631 ALA ALA A . n 
A 1 626 ARG 626 632 632 ARG ARG A . n 
A 1 627 LEU 627 633 633 LEU LEU A . n 
A 1 628 THR 628 634 634 THR THR A . n 
A 1 629 GLY 629 635 635 GLY GLY A . n 
A 1 630 LYS 630 636 636 LYS LYS A . n 
A 1 631 TYR 631 637 637 TYR TYR A . n 
A 1 632 LYS 632 638 638 LYS LYS A . n 
A 1 633 PHE 633 639 639 PHE PHE A . n 
A 1 634 VAL 634 640 640 VAL VAL A . n 
A 1 635 ILE 635 641 641 ILE ILE A . n 
A 1 636 LYS 636 642 642 LYS LYS A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 ZN  1   701  1   ZN  ZN  A . 
C 3 HOH 1   801  26  HOH HOH A . 
C 3 HOH 2   802  191 HOH HOH A . 
C 3 HOH 3   803  369 HOH HOH A . 
C 3 HOH 4   804  431 HOH HOH A . 
C 3 HOH 5   805  215 HOH HOH A . 
C 3 HOH 6   806  117 HOH HOH A . 
C 3 HOH 7   807  186 HOH HOH A . 
C 3 HOH 8   808  98  HOH HOH A . 
C 3 HOH 9   809  328 HOH HOH A . 
C 3 HOH 10  810  166 HOH HOH A . 
C 3 HOH 11  811  479 HOH HOH A . 
C 3 HOH 12  812  403 HOH HOH A . 
C 3 HOH 13  813  77  HOH HOH A . 
C 3 HOH 14  814  451 HOH HOH A . 
C 3 HOH 15  815  177 HOH HOH A . 
C 3 HOH 16  816  452 HOH HOH A . 
C 3 HOH 17  817  2   HOH HOH A . 
C 3 HOH 18  818  67  HOH HOH A . 
C 3 HOH 19  819  71  HOH HOH A . 
C 3 HOH 20  820  213 HOH HOH A . 
C 3 HOH 21  821  380 HOH HOH A . 
C 3 HOH 22  822  249 HOH HOH A . 
C 3 HOH 23  823  4   HOH HOH A . 
C 3 HOH 24  824  382 HOH HOH A . 
C 3 HOH 25  825  105 HOH HOH A . 
C 3 HOH 26  826  330 HOH HOH A . 
C 3 HOH 27  827  173 HOH HOH A . 
C 3 HOH 28  828  352 HOH HOH A . 
C 3 HOH 29  829  70  HOH HOH A . 
C 3 HOH 30  830  241 HOH HOH A . 
C 3 HOH 31  831  23  HOH HOH A . 
C 3 HOH 32  832  79  HOH HOH A . 
C 3 HOH 33  833  234 HOH HOH A . 
C 3 HOH 34  834  394 HOH HOH A . 
C 3 HOH 35  835  126 HOH HOH A . 
C 3 HOH 36  836  69  HOH HOH A . 
C 3 HOH 37  837  371 HOH HOH A . 
C 3 HOH 38  838  459 HOH HOH A . 
C 3 HOH 39  839  61  HOH HOH A . 
C 3 HOH 40  840  35  HOH HOH A . 
C 3 HOH 41  841  404 HOH HOH A . 
C 3 HOH 42  842  413 HOH HOH A . 
C 3 HOH 43  843  483 HOH HOH A . 
C 3 HOH 44  844  414 HOH HOH A . 
C 3 HOH 45  845  598 HOH HOH A . 
C 3 HOH 46  846  89  HOH HOH A . 
C 3 HOH 47  847  336 HOH HOH A . 
C 3 HOH 48  848  43  HOH HOH A . 
C 3 HOH 49  849  33  HOH HOH A . 
C 3 HOH 50  850  538 HOH HOH A . 
C 3 HOH 51  851  199 HOH HOH A . 
C 3 HOH 52  852  407 HOH HOH A . 
C 3 HOH 53  853  149 HOH HOH A . 
C 3 HOH 54  854  206 HOH HOH A . 
C 3 HOH 55  855  93  HOH HOH A . 
C 3 HOH 56  856  319 HOH HOH A . 
C 3 HOH 57  857  86  HOH HOH A . 
C 3 HOH 58  858  15  HOH HOH A . 
C 3 HOH 59  859  289 HOH HOH A . 
C 3 HOH 60  860  103 HOH HOH A . 
C 3 HOH 61  861  402 HOH HOH A . 
C 3 HOH 62  862  425 HOH HOH A . 
C 3 HOH 63  863  434 HOH HOH A . 
C 3 HOH 64  864  560 HOH HOH A . 
C 3 HOH 65  865  245 HOH HOH A . 
C 3 HOH 66  866  143 HOH HOH A . 
C 3 HOH 67  867  294 HOH HOH A . 
C 3 HOH 68  868  152 HOH HOH A . 
C 3 HOH 69  869  100 HOH HOH A . 
C 3 HOH 70  870  32  HOH HOH A . 
C 3 HOH 71  871  12  HOH HOH A . 
C 3 HOH 72  872  22  HOH HOH A . 
C 3 HOH 73  873  600 HOH HOH A . 
C 3 HOH 74  874  252 HOH HOH A . 
C 3 HOH 75  875  357 HOH HOH A . 
C 3 HOH 76  876  561 HOH HOH A . 
C 3 HOH 77  877  405 HOH HOH A . 
C 3 HOH 78  878  107 HOH HOH A . 
C 3 HOH 79  879  201 HOH HOH A . 
C 3 HOH 80  880  392 HOH HOH A . 
C 3 HOH 81  881  592 HOH HOH A . 
C 3 HOH 82  882  137 HOH HOH A . 
C 3 HOH 83  883  398 HOH HOH A . 
C 3 HOH 84  884  310 HOH HOH A . 
C 3 HOH 85  885  176 HOH HOH A . 
C 3 HOH 86  886  466 HOH HOH A . 
C 3 HOH 87  887  115 HOH HOH A . 
C 3 HOH 88  888  324 HOH HOH A . 
C 3 HOH 89  889  255 HOH HOH A . 
C 3 HOH 90  890  162 HOH HOH A . 
C 3 HOH 91  891  597 HOH HOH A . 
C 3 HOH 92  892  37  HOH HOH A . 
C 3 HOH 93  893  593 HOH HOH A . 
C 3 HOH 94  894  118 HOH HOH A . 
C 3 HOH 95  895  203 HOH HOH A . 
C 3 HOH 96  896  140 HOH HOH A . 
C 3 HOH 97  897  95  HOH HOH A . 
C 3 HOH 98  898  304 HOH HOH A . 
C 3 HOH 99  899  125 HOH HOH A . 
C 3 HOH 100 900  393 HOH HOH A . 
C 3 HOH 101 901  504 HOH HOH A . 
C 3 HOH 102 902  282 HOH HOH A . 
C 3 HOH 103 903  485 HOH HOH A . 
C 3 HOH 104 904  453 HOH HOH A . 
C 3 HOH 105 905  49  HOH HOH A . 
C 3 HOH 106 906  385 HOH HOH A . 
C 3 HOH 107 907  478 HOH HOH A . 
C 3 HOH 108 908  205 HOH HOH A . 
C 3 HOH 109 909  372 HOH HOH A . 
C 3 HOH 110 910  381 HOH HOH A . 
C 3 HOH 111 911  410 HOH HOH A . 
C 3 HOH 112 912  214 HOH HOH A . 
C 3 HOH 113 913  136 HOH HOH A . 
C 3 HOH 114 914  430 HOH HOH A . 
C 3 HOH 115 915  207 HOH HOH A . 
C 3 HOH 116 916  595 HOH HOH A . 
C 3 HOH 117 917  94  HOH HOH A . 
C 3 HOH 118 918  134 HOH HOH A . 
C 3 HOH 119 919  165 HOH HOH A . 
C 3 HOH 120 920  209 HOH HOH A . 
C 3 HOH 121 921  171 HOH HOH A . 
C 3 HOH 122 922  147 HOH HOH A . 
C 3 HOH 123 923  36  HOH HOH A . 
C 3 HOH 124 924  68  HOH HOH A . 
C 3 HOH 125 925  148 HOH HOH A . 
C 3 HOH 126 926  6   HOH HOH A . 
C 3 HOH 127 927  377 HOH HOH A . 
C 3 HOH 128 928  599 HOH HOH A . 
C 3 HOH 129 929  110 HOH HOH A . 
C 3 HOH 130 930  21  HOH HOH A . 
C 3 HOH 131 931  211 HOH HOH A . 
C 3 HOH 132 932  153 HOH HOH A . 
C 3 HOH 133 933  19  HOH HOH A . 
C 3 HOH 134 934  106 HOH HOH A . 
C 3 HOH 135 935  170 HOH HOH A . 
C 3 HOH 136 936  331 HOH HOH A . 
C 3 HOH 137 937  119 HOH HOH A . 
C 3 HOH 138 938  25  HOH HOH A . 
C 3 HOH 139 939  358 HOH HOH A . 
C 3 HOH 140 940  491 HOH HOH A . 
C 3 HOH 141 941  3   HOH HOH A . 
C 3 HOH 142 942  531 HOH HOH A . 
C 3 HOH 143 943  322 HOH HOH A . 
C 3 HOH 144 944  128 HOH HOH A . 
C 3 HOH 145 945  73  HOH HOH A . 
C 3 HOH 146 946  123 HOH HOH A . 
C 3 HOH 147 947  114 HOH HOH A . 
C 3 HOH 148 948  281 HOH HOH A . 
C 3 HOH 149 949  274 HOH HOH A . 
C 3 HOH 150 950  225 HOH HOH A . 
C 3 HOH 151 951  97  HOH HOH A . 
C 3 HOH 152 952  82  HOH HOH A . 
C 3 HOH 153 953  47  HOH HOH A . 
C 3 HOH 154 954  104 HOH HOH A . 
C 3 HOH 155 955  355 HOH HOH A . 
C 3 HOH 156 956  122 HOH HOH A . 
C 3 HOH 157 957  437 HOH HOH A . 
C 3 HOH 158 958  396 HOH HOH A . 
C 3 HOH 159 959  506 HOH HOH A . 
C 3 HOH 160 960  235 HOH HOH A . 
C 3 HOH 161 961  50  HOH HOH A . 
C 3 HOH 162 962  196 HOH HOH A . 
C 3 HOH 163 963  56  HOH HOH A . 
C 3 HOH 164 964  401 HOH HOH A . 
C 3 HOH 165 965  8   HOH HOH A . 
C 3 HOH 166 966  39  HOH HOH A . 
C 3 HOH 167 967  273 HOH HOH A . 
C 3 HOH 168 968  65  HOH HOH A . 
C 3 HOH 169 969  594 HOH HOH A . 
C 3 HOH 170 970  127 HOH HOH A . 
C 3 HOH 171 971  424 HOH HOH A . 
C 3 HOH 172 972  343 HOH HOH A . 
C 3 HOH 173 973  302 HOH HOH A . 
C 3 HOH 174 974  66  HOH HOH A . 
C 3 HOH 175 975  13  HOH HOH A . 
C 3 HOH 176 976  45  HOH HOH A . 
C 3 HOH 177 977  101 HOH HOH A . 
C 3 HOH 178 978  194 HOH HOH A . 
C 3 HOH 179 979  146 HOH HOH A . 
C 3 HOH 180 980  179 HOH HOH A . 
C 3 HOH 181 981  131 HOH HOH A . 
C 3 HOH 182 982  10  HOH HOH A . 
C 3 HOH 183 983  41  HOH HOH A . 
C 3 HOH 184 984  267 HOH HOH A . 
C 3 HOH 185 985  88  HOH HOH A . 
C 3 HOH 186 986  426 HOH HOH A . 
C 3 HOH 187 987  85  HOH HOH A . 
C 3 HOH 188 988  387 HOH HOH A . 
C 3 HOH 189 989  124 HOH HOH A . 
C 3 HOH 190 990  92  HOH HOH A . 
C 3 HOH 191 991  216 HOH HOH A . 
C 3 HOH 192 992  9   HOH HOH A . 
C 3 HOH 193 993  473 HOH HOH A . 
C 3 HOH 194 994  379 HOH HOH A . 
C 3 HOH 195 995  339 HOH HOH A . 
C 3 HOH 196 996  580 HOH HOH A . 
C 3 HOH 197 997  411 HOH HOH A . 
C 3 HOH 198 998  499 HOH HOH A . 
C 3 HOH 199 999  423 HOH HOH A . 
C 3 HOH 200 1000 54  HOH HOH A . 
C 3 HOH 201 1001 44  HOH HOH A . 
C 3 HOH 202 1002 299 HOH HOH A . 
C 3 HOH 203 1003 261 HOH HOH A . 
C 3 HOH 204 1004 334 HOH HOH A . 
C 3 HOH 205 1005 266 HOH HOH A . 
C 3 HOH 206 1006 40  HOH HOH A . 
C 3 HOH 207 1007 288 HOH HOH A . 
C 3 HOH 208 1008 450 HOH HOH A . 
C 3 HOH 209 1009 120 HOH HOH A . 
C 3 HOH 210 1010 445 HOH HOH A . 
C 3 HOH 211 1011 63  HOH HOH A . 
C 3 HOH 212 1012 383 HOH HOH A . 
C 3 HOH 213 1013 90  HOH HOH A . 
C 3 HOH 214 1014 109 HOH HOH A . 
C 3 HOH 215 1015 18  HOH HOH A . 
C 3 HOH 216 1016 374 HOH HOH A . 
C 3 HOH 217 1017 275 HOH HOH A . 
C 3 HOH 218 1018 46  HOH HOH A . 
C 3 HOH 219 1019 11  HOH HOH A . 
C 3 HOH 220 1020 222 HOH HOH A . 
C 3 HOH 221 1021 17  HOH HOH A . 
C 3 HOH 222 1022 138 HOH HOH A . 
C 3 HOH 223 1023 154 HOH HOH A . 
C 3 HOH 224 1024 7   HOH HOH A . 
C 3 HOH 225 1025 231 HOH HOH A . 
C 3 HOH 226 1026 113 HOH HOH A . 
C 3 HOH 227 1027 60  HOH HOH A . 
C 3 HOH 228 1028 182 HOH HOH A . 
C 3 HOH 229 1029 27  HOH HOH A . 
C 3 HOH 230 1030 112 HOH HOH A . 
C 3 HOH 231 1031 1   HOH HOH A . 
C 3 HOH 232 1032 80  HOH HOH A . 
C 3 HOH 233 1033 38  HOH HOH A . 
C 3 HOH 234 1034 505 HOH HOH A . 
C 3 HOH 235 1035 129 HOH HOH A . 
C 3 HOH 236 1036 187 HOH HOH A . 
C 3 HOH 237 1037 76  HOH HOH A . 
C 3 HOH 238 1038 297 HOH HOH A . 
C 3 HOH 239 1039 432 HOH HOH A . 
C 3 HOH 240 1040 596 HOH HOH A . 
C 3 HOH 241 1041 185 HOH HOH A . 
C 3 HOH 242 1042 498 HOH HOH A . 
C 3 HOH 243 1043 192 HOH HOH A . 
C 3 HOH 244 1044 390 HOH HOH A . 
C 3 HOH 245 1045 172 HOH HOH A . 
C 3 HOH 246 1046 74  HOH HOH A . 
C 3 HOH 247 1047 409 HOH HOH A . 
C 3 HOH 248 1048 448 HOH HOH A . 
C 3 HOH 249 1049 155 HOH HOH A . 
C 3 HOH 250 1050 438 HOH HOH A . 
C 3 HOH 251 1051 99  HOH HOH A . 
C 3 HOH 252 1052 439 HOH HOH A . 
C 3 HOH 253 1053 444 HOH HOH A . 
C 3 HOH 254 1054 158 HOH HOH A . 
C 3 HOH 255 1055 391 HOH HOH A . 
C 3 HOH 256 1056 321 HOH HOH A . 
C 3 HOH 257 1057 388 HOH HOH A . 
C 3 HOH 258 1058 142 HOH HOH A . 
C 3 HOH 259 1059 30  HOH HOH A . 
C 3 HOH 260 1060 465 HOH HOH A . 
C 3 HOH 261 1061 373 HOH HOH A . 
C 3 HOH 262 1062 164 HOH HOH A . 
C 3 HOH 263 1063 121 HOH HOH A . 
C 3 HOH 264 1064 193 HOH HOH A . 
C 3 HOH 265 1065 399 HOH HOH A . 
C 3 HOH 266 1066 240 HOH HOH A . 
C 3 HOH 267 1067 160 HOH HOH A . 
C 3 HOH 268 1068 467 HOH HOH A . 
C 3 HOH 269 1069 53  HOH HOH A . 
C 3 HOH 270 1070 190 HOH HOH A . 
C 3 HOH 271 1071 150 HOH HOH A . 
C 3 HOH 272 1072 20  HOH HOH A . 
C 3 HOH 273 1073 589 HOH HOH A . 
C 3 HOH 274 1074 132 HOH HOH A . 
C 3 HOH 275 1075 5   HOH HOH A . 
C 3 HOH 276 1076 375 HOH HOH A . 
C 3 HOH 277 1077 349 HOH HOH A . 
C 3 HOH 278 1078 208 HOH HOH A . 
C 3 HOH 279 1079 248 HOH HOH A . 
C 3 HOH 280 1080 48  HOH HOH A . 
C 3 HOH 281 1081 217 HOH HOH A . 
C 3 HOH 282 1082 464 HOH HOH A . 
C 3 HOH 283 1083 408 HOH HOH A . 
C 3 HOH 284 1084 420 HOH HOH A . 
C 3 HOH 285 1085 582 HOH HOH A . 
C 3 HOH 286 1086 348 HOH HOH A . 
C 3 HOH 287 1087 227 HOH HOH A . 
C 3 HOH 288 1088 590 HOH HOH A . 
C 3 HOH 289 1089 517 HOH HOH A . 
C 3 HOH 290 1090 351 HOH HOH A . 
C 3 HOH 291 1091 263 HOH HOH A . 
C 3 HOH 292 1092 111 HOH HOH A . 
C 3 HOH 293 1093 239 HOH HOH A . 
C 3 HOH 294 1094 581 HOH HOH A . 
C 3 HOH 295 1095 389 HOH HOH A . 
C 3 HOH 296 1096 587 HOH HOH A . 
C 3 HOH 297 1097 344 HOH HOH A . 
C 3 HOH 298 1098 586 HOH HOH A . 
C 3 HOH 299 1099 180 HOH HOH A . 
C 3 HOH 300 1100 279 HOH HOH A . 
C 3 HOH 301 1101 360 HOH HOH A . 
C 3 HOH 302 1102 350 HOH HOH A . 
C 3 HOH 303 1103 236 HOH HOH A . 
C 3 HOH 304 1104 354 HOH HOH A . 
C 3 HOH 305 1105 542 HOH HOH A . 
C 3 HOH 306 1106 228 HOH HOH A . 
C 3 HOH 307 1107 157 HOH HOH A . 
C 3 HOH 308 1108 244 HOH HOH A . 
C 3 HOH 309 1109 584 HOH HOH A . 
C 3 HOH 310 1110 198 HOH HOH A . 
C 3 HOH 311 1111 306 HOH HOH A . 
C 3 HOH 312 1112 591 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0419 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   109.28 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R73 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     103.63 
_cell.length_a_esd                 ? 
_cell.length_b                     91.39 
_cell.length_b_esd                 ? 
_cell.length_c                     84.77 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R73 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R73 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.60 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.75 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;10 % PEG 8000
8 % Ethylene glycol
0.1 M HEPES pH 7.5
28 mg/ml
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            295 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-03-23 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    0.96 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9763 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9763 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8R73 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.11 
_reflns.d_resolution_low                               40.01 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     42837 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.7 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          10.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1.00 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.11 
_reflns_shell.d_res_low                                     2.17 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.5 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3507 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.70 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.029 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            0.781 
_refine.aniso_B[2][2]                            1.831 
_refine.aniso_B[2][3]                            0.000 
_refine.aniso_B[3][3]                            -1.933 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               42.933 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.961 
_refine.correlation_coeff_Fo_to_Fc_free          0.928 
_refine.details                                  'Hydrogens have been added in their riding positions' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8R73 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.110 
_refine.ls_d_res_low                             40.008 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     42836 
_refine.ls_number_reflns_R_free                  2098 
_refine.ls_number_reflns_R_work                  40738 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.721 
_refine.ls_percent_reflns_R_free                 4.898 
_refine.ls_R_factor_all                          0.192 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.2502 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1888 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.211 
_refine.pdbx_overall_ESU_R_Free                  0.194 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             6.432 
_refine.overall_SU_ML                            0.161 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        4981 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         1 
_refine_hist.number_atoms_solvent             312 
_refine_hist.number_atoms_total               5294 
_refine_hist.d_res_high                       2.110 
_refine_hist.d_res_low                        40.008 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  5109  ? r_bond_refined_d               ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  4709  ? r_bond_other_d                 ? ? 
'X-RAY DIFFRACTION' ? 1.826  1.817  6929  ? r_angle_refined_deg            ? ? 
'X-RAY DIFFRACTION' ? 0.613  1.765  10816 ? r_angle_other_deg              ? ? 
'X-RAY DIFFRACTION' ? 7.155  5.000  616   ? r_dihedral_angle_1_deg         ? ? 
'X-RAY DIFFRACTION' ? 11.723 5.000  32    ? r_dihedral_angle_2_deg         ? ? 
'X-RAY DIFFRACTION' ? 14.869 10.000 859   ? r_dihedral_angle_3_deg         ? ? 
'X-RAY DIFFRACTION' ? 14.934 10.000 253   ? r_dihedral_angle_6_deg         ? ? 
'X-RAY DIFFRACTION' ? 0.090  0.200  726   ? r_chiral_restr                 ? ? 
'X-RAY DIFFRACTION' ? 0.009  0.020  6170  ? r_gen_planes_refined           ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  1278  ? r_gen_planes_other             ? ? 
'X-RAY DIFFRACTION' ? 0.215  0.200  1042  ? r_nbd_refined                  ? ? 
'X-RAY DIFFRACTION' ? 0.192  0.200  4329  ? r_symmetry_nbd_other           ? ? 
'X-RAY DIFFRACTION' ? 0.188  0.200  2486  ? r_nbtor_refined                ? ? 
'X-RAY DIFFRACTION' ? 0.081  0.200  2729  ? r_symmetry_nbtor_other         ? ? 
'X-RAY DIFFRACTION' ? 0.156  0.200  283   ? r_xyhbond_nbd_refined          ? ? 
'X-RAY DIFFRACTION' ? 0.153  0.200  5     ? r_symmetry_nbd_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.138  0.200  69    ? r_nbd_other                    ? ? 
'X-RAY DIFFRACTION' ? 0.160  0.200  28    ? r_symmetry_xyhbond_nbd_refined ? ? 
'X-RAY DIFFRACTION' ? 3.774  4.045  2467  ? r_mcbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 3.771  4.045  2467  ? r_mcbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 4.812  7.272  3082  ? r_mcangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 4.813  7.273  3083  ? r_mcangle_other                ? ? 
'X-RAY DIFFRACTION' ? 4.791  4.426  2642  ? r_scbond_it                    ? ? 
'X-RAY DIFFRACTION' ? 4.790  4.427  2643  ? r_scbond_other                 ? ? 
'X-RAY DIFFRACTION' ? 6.721  7.942  3847  ? r_scangle_it                   ? ? 
'X-RAY DIFFRACTION' ? 6.721  7.943  3848  ? r_scangle_other                ? ? 
'X-RAY DIFFRACTION' ? 7.955  39.831 5953  ? r_lrange_it                    ? ? 
'X-RAY DIFFRACTION' ? 7.966  39.415 5898  ? r_lrange_other                 ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.110 2.165  3153 . 156 2996 99.9683  . 0.307 . . 0.306 . . . . . 0.287 . 20 . 0.929 0.923 0.327 
'X-RAY DIFFRACTION' 2.165 2.224  3069 . 148 2920 99.9674  . 0.279 . . 0.276 . . . . . 0.251 . 20 . 0.946 0.931 0.324 
'X-RAY DIFFRACTION' 2.224 2.288  2979 . 135 2837 99.7650  . 0.263 . . 0.259 . . . . . 0.231 . 20 . 0.954 0.928 0.355 
'X-RAY DIFFRACTION' 2.288 2.358  2910 . 143 2767 100.0000 . 0.234 . . 0.231 . . . . . 0.198 . 20 . 0.963 0.942 0.296 
'X-RAY DIFFRACTION' 2.358 2.435  2808 . 151 2656 99.9644  . 0.234 . . 0.229 . . . . . 0.195 . 20 . 0.966 0.937 0.317 
'X-RAY DIFFRACTION' 2.435 2.520  2721 . 130 2590 99.9632  . 0.222 . . 0.219 . . . . . 0.186 . 20 . 0.971 0.944 0.285 
'X-RAY DIFFRACTION' 2.520 2.615  2640 . 114 2521 99.8106  . 0.190 . . 0.187 . . . . . 0.158 . 20 . 0.979 0.952 0.276 
'X-RAY DIFFRACTION' 2.615 2.722  2539 . 123 2408 99.6849  . 0.188 . . 0.184 . . . . . 0.158 . 20 . 0.980 0.961 0.258 
'X-RAY DIFFRACTION' 2.722 2.842  2438 . 114 2308 99.3437  . 0.199 . . 0.195 . . . . . 0.170 . 20 . 0.977 0.955 0.265 
'X-RAY DIFFRACTION' 2.842 2.980  2334 . 114 2208 99.4859  . 0.177 . . 0.174 . . . . . 0.158 . 20 . 0.982 0.965 0.236 
'X-RAY DIFFRACTION' 2.980 3.140  2249 . 105 2133 99.5109  . 0.194 . . 0.191 . . . . . 0.179 . 20 . 0.981 0.957 0.263 
'X-RAY DIFFRACTION' 3.140 3.329  2072 . 111 1953 99.6139  . 0.216 . . 0.213 . . . . . 0.203 . 20 . 0.976 0.947 0.276 
'X-RAY DIFFRACTION' 3.329 3.557  1969 . 91  1875 99.8476  . 0.212 . . 0.211 . . . . . 0.205 . 20 . 0.979 0.968 0.247 
'X-RAY DIFFRACTION' 3.557 3.840  1853 . 81  1770 99.8921  . 0.181 . . 0.179 . . . . . 0.179 . 20 . 0.984 0.974 0.218 
'X-RAY DIFFRACTION' 3.840 4.203  1678 . 76  1601 99.9404  . 0.148 . . 0.145 . . . . . 0.151 . 20 . 0.988 0.976 0.198 
'X-RAY DIFFRACTION' 4.203 4.692  1550 . 89  1453 99.4839  . 0.140 . . 0.136 . . . . . 0.150 . 20 . 0.990 0.980 0.210 
'X-RAY DIFFRACTION' 4.692 5.406  1375 . 81  1269 98.1818  . 0.154 . . 0.150 . . . . . 0.167 . 20 . 0.989 0.976 0.218 
'X-RAY DIFFRACTION' 5.406 6.591  1151 . 62  1086 99.7394  . 0.194 . . 0.188 . . . . . 0.203 . 20 . 0.983 0.952 0.293 
'X-RAY DIFFRACTION' 6.591 9.197  918  . 47  871  100.0000 . 0.178 . . 0.177 . . . . . 0.205 . 20 . 0.983 0.980 0.186 
'X-RAY DIFFRACTION' 9.197 40.008 543  . 27  516  100.0000 . 0.171 . . 0.167 . . . . . 0.200 . 20 . 0.985 0.965 0.251 
# 
_struct.entry_id                     8R73 
_struct.title                        'Polysaccharide lyase BcPL33HA (BcellWH2_04512) Apo form' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R73 
_struct_keywords.text            'Polysaccharide lyase, glycosaminoglycan, Hyaluronic acid, conformational change, LYASE' 
_struct_keywords.pdbx_keywords   LYASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A0P0GKX0_9BACE 
_struct_ref.pdbx_db_accession          A0A0P0GKX0 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;YTERNLLQKAAGSEEQLKEALVMNQKWVPYPAYNDRAGWNELLGTNKESLIRAGEKMLNYEWKVIRATDYLEYERSGERN
IMQNPYEANRKAINALMLAELAEGKGRFIDQLINGAFYSCEMTSWVLSAHLVRQSTKRSLPDYREQVIDLGSGNFGSMLS
WVYYFFHDSFDKIDPVISQRLRHTLQERILDPYMNNDREWWMAFQWKPGMIINNWNPWCNSNVLQCYLLLENDRDRLAKA
VWRSMQSVDKFINFVKADGACEEGPSYWGHAAGKMYDYLQILSDGTDGKVSLFKEPMIRRMGEYISRTYVGNGWVVNFAD
ASAKGGGDAPLIYRYGRAVGSEEMMQFAAYLLDGKRPSVPLGNDTFRSLQSILWNGELEKTTAAHTIPACTWYPETEFCY
LTNKSGWFLATKGGFNNESHNHNDVGTFSLYVNTIPVLIDAGVGTYTRQTFSSERYTIWTMQSNYHNLPMINGVPQSFGQ
NYKATDVVCQPKKRFFSANIATAYPKEAEVNSWTRAYSLGDKQLTITDNFSLKSAKESNQVNFLTWGKVDISVPGKVTID
VQGQKVTLEYPGEFTATVETINLPDTRLSNVWGTEIYRIALKDKDARLTGKYKFVIK
;
_struct_ref.pdbx_align_begin           26 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8R73 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 20 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 636 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A0P0GKX0 
_struct_ref_seq.db_align_beg                  26 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  642 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       26 
_struct_ref_seq.pdbx_auth_seq_align_end       642 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8R73 MET A 1  ? UNP A0A0P0GKX0 ? ? 'initiating methionine' 7  1  
1 8R73 GLY A 2  ? UNP A0A0P0GKX0 ? ? 'expression tag'        8  2  
1 8R73 SER A 3  ? UNP A0A0P0GKX0 ? ? 'expression tag'        9  3  
1 8R73 SER A 4  ? UNP A0A0P0GKX0 ? ? 'expression tag'        10 4  
1 8R73 HIS A 5  ? UNP A0A0P0GKX0 ? ? 'expression tag'        11 5  
1 8R73 HIS A 6  ? UNP A0A0P0GKX0 ? ? 'expression tag'        12 6  
1 8R73 HIS A 7  ? UNP A0A0P0GKX0 ? ? 'expression tag'        13 7  
1 8R73 HIS A 8  ? UNP A0A0P0GKX0 ? ? 'expression tag'        14 8  
1 8R73 HIS A 9  ? UNP A0A0P0GKX0 ? ? 'expression tag'        15 9  
1 8R73 HIS A 10 ? UNP A0A0P0GKX0 ? ? 'expression tag'        16 10 
1 8R73 SER A 11 ? UNP A0A0P0GKX0 ? ? 'expression tag'        17 11 
1 8R73 SER A 12 ? UNP A0A0P0GKX0 ? ? 'expression tag'        18 12 
1 8R73 GLY A 13 ? UNP A0A0P0GKX0 ? ? 'expression tag'        19 13 
1 8R73 PRO A 14 ? UNP A0A0P0GKX0 ? ? 'expression tag'        20 14 
1 8R73 GLN A 15 ? UNP A0A0P0GKX0 ? ? 'expression tag'        21 15 
1 8R73 GLN A 16 ? UNP A0A0P0GKX0 ? ? 'expression tag'        22 16 
1 8R73 GLY A 17 ? UNP A0A0P0GKX0 ? ? 'expression tag'        23 17 
1 8R73 LEU A 18 ? UNP A0A0P0GKX0 ? ? 'expression tag'        24 18 
1 8R73 ARG A 19 ? UNP A0A0P0GKX0 ? ? 'expression tag'        25 19 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   SAXS 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASN A 24  ? GLY A 31  ? ASN A 30  GLY A 37  1 ? 8  
HELX_P HELX_P2  AA2 SER A 32  ? LEU A 40  ? SER A 38  LEU A 46  1 ? 9  
HELX_P HELX_P3  AA3 ASP A 54  ? GLY A 63  ? ASP A 60  GLY A 69  1 ? 10 
HELX_P HELX_P4  AA4 THR A 64  ? MET A 76  ? THR A 70  MET A 82  1 ? 13 
HELX_P HELX_P5  AA5 LEU A 77  ? TYR A 79  ? LEU A 83  TYR A 85  5 ? 3  
HELX_P HELX_P6  AA6 ARG A 85  ? GLY A 96  ? ARG A 91  GLY A 102 1 ? 12 
HELX_P HELX_P7  AA7 ARG A 98  ? GLY A 123 ? ARG A 104 GLY A 129 1 ? 26 
HELX_P HELX_P8  AA8 PHE A 127 ? MET A 141 ? PHE A 133 MET A 147 1 ? 15 
HELX_P HELX_P9  AA9 LEU A 146 ? GLN A 153 ? LEU A 152 GLN A 159 5 ? 8  
HELX_P HELX_P10 AB1 ASP A 168 ? ASP A 193 ? ASP A 174 ASP A 199 1 ? 26 
HELX_P HELX_P11 AB2 PRO A 194 ? ILE A 208 ? PRO A 200 ILE A 214 1 ? 15 
HELX_P HELX_P12 AB3 ILE A 208 ? ASN A 215 ? ILE A 214 ASN A 221 1 ? 8  
HELX_P HELX_P13 AB4 GLU A 218 ? ALA A 222 ? GLU A 224 ALA A 228 5 ? 5  
HELX_P HELX_P14 AB5 ASN A 233 ? GLU A 250 ? ASN A 239 GLU A 256 1 ? 18 
HELX_P HELX_P15 AB6 ASP A 252 ? VAL A 274 ? ASP A 258 VAL A 280 1 ? 23 
HELX_P HELX_P16 AB7 TYR A 286 ? HIS A 289 ? TYR A 292 HIS A 295 5 ? 4  
HELX_P HELX_P17 AB8 ALA A 290 ? THR A 305 ? ALA A 296 THR A 311 1 ? 16 
HELX_P HELX_P18 AB9 GLU A 314 ? THR A 327 ? GLU A 320 THR A 333 1 ? 14 
HELX_P HELX_P19 AC1 ASP A 347 ? GLY A 359 ? ASP A 353 GLY A 365 1 ? 13 
HELX_P HELX_P20 AC2 SER A 360 ? LEU A 371 ? SER A 366 LEU A 377 1 ? 12 
HELX_P HELX_P21 AC3 ASP A 383 ? THR A 400 ? ASP A 389 THR A 406 1 ? 18 
HELX_P HELX_P22 AC4 GLU A 473 ? HIS A 485 ? GLU A 479 HIS A 491 5 ? 13 
HELX_P HELX_P23 AC5 ILE A 490 ? VAL A 493 ? ILE A 496 VAL A 499 5 ? 4  
HELX_P HELX_P24 AC6 PRO A 510 ? LYS A 512 ? PRO A 516 LYS A 518 5 ? 3  
HELX_P HELX_P25 AC7 ALA A 520 ? TYR A 523 ? ALA A 526 TYR A 529 5 ? 4  
HELX_P HELX_P26 AC8 PRO A 524 ? ALA A 527 ? PRO A 530 ALA A 533 5 ? 4  
HELX_P HELX_P27 AC9 ASP A 604 ? GLY A 612 ? ASP A 610 GLY A 618 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A HIS 441 ND1 ? ? ? 1_555 B ZN  . ZN ? ? A HIS 447 A ZN  701 1_555 ? ? ? ? ? ? ? 2.225 ? ? 
metalc2 metalc ? ? A ASP 459 OD1 ? ? ? 1_555 B ZN  . ZN ? ? A ASP 465 A ZN  701 1_555 ? ? ? ? ? ? ? 2.076 ? ? 
metalc3 metalc ? ? A HIS 485 NE2 ? ? ? 1_555 B ZN  . ZN ? ? A HIS 491 A ZN  701 1_555 ? ? ? ? ? ? ? 2.249 ? ? 
metalc4 metalc ? ? B ZN  .   ZN  ? ? ? 1_555 C HOH . O  ? ? A ZN  701 A HOH 881 1_555 ? ? ? ? ? ? ? 2.163 ? ? 
metalc5 metalc ? ? B ZN  .   ZN  ? ? ? 1_555 C HOH . O  ? ? A ZN  701 A HOH 893 1_555 ? ? ? ? ? ? ? 2.174 ? ? 
metalc6 metalc ? ? B ZN  .   ZN  ? ? ? 1_555 C HOH . O  ? ? A ZN  701 A HOH 969 1_555 ? ? ? ? ? ? ? 2.303 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  ND1 ? A HIS 441 ? A HIS 447 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 OD1 ? A ASP 459 ? A ASP 465 ? 1_555 162.6 ? 
2  ND1 ? A HIS 441 ? A HIS 447 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 NE2 ? A HIS 485 ? A HIS 491 ? 1_555 101.4 ? 
3  OD1 ? A ASP 459 ? A ASP 465 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 NE2 ? A HIS 485 ? A HIS 491 ? 1_555 93.6  ? 
4  ND1 ? A HIS 441 ? A HIS 447 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 881 ? 1_555 87.0  ? 
5  OD1 ? A ASP 459 ? A ASP 465 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 881 ? 1_555 77.7  ? 
6  NE2 ? A HIS 485 ? A HIS 491 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 881 ? 1_555 171.2 ? 
7  ND1 ? A HIS 441 ? A HIS 447 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 893 ? 1_555 99.3  ? 
8  OD1 ? A ASP 459 ? A ASP 465 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 893 ? 1_555 88.5  ? 
9  NE2 ? A HIS 485 ? A HIS 491 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 893 ? 1_555 93.4  ? 
10 O   ? C HOH .   ? A HOH 881 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 893 ? 1_555 87.6  ? 
11 ND1 ? A HIS 441 ? A HIS 447 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 969 ? 1_555 91.7  ? 
12 OD1 ? A ASP 459 ? A ASP 465 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 969 ? 1_555 80.4  ? 
13 NE2 ? A HIS 485 ? A HIS 491 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 969 ? 1_555 86.6  ? 
14 O   ? C HOH .   ? A HOH 881 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 969 ? 1_555 90.7  ? 
15 O   ? C HOH .   ? A HOH 893 ? 1_555 ZN ? B ZN . ? A ZN 701 ? 1_555 O   ? C HOH .   ? A HOH 969 ? 1_555 168.8 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 5 ? 
AA3 ? 2 ? 
AA4 ? 4 ? 
AA5 ? 8 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
AA5 7 8 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TYR A 328 ? GLY A 330 ? TYR A 334 GLY A 336 
AA1 2 TRP A 333 ? VAL A 334 ? TRP A 339 VAL A 340 
AA2 1 CYS A 409 ? TYR A 412 ? CYS A 415 TYR A 418 
AA2 2 PHE A 417 ? THR A 421 ? PHE A 423 THR A 427 
AA2 3 TRP A 426 ? LYS A 431 ? TRP A 432 LYS A 437 
AA2 4 PHE A 447 ? VAL A 451 ? PHE A 453 VAL A 457 
AA2 5 ILE A 454 ? LEU A 457 ? ILE A 460 LEU A 463 
AA3 1 PHE A 434 ? ASN A 435 ? PHE A 440 ASN A 441 
AA3 2 GLY A 498 ? LYS A 502 ? GLY A 504 LYS A 508 
AA4 1 PRO A 488 ? MET A 489 ? PRO A 494 MET A 495 
AA4 2 GLN A 559 ? THR A 564 ? GLN A 565 THR A 570 
AA4 3 GLU A 614 ? ASP A 622 ? GLU A 620 ASP A 628 
AA4 4 PHE A 593 ? ASN A 601 ? PHE A 599 ASN A 607 
AA5 1 THR A 504 ? GLN A 509 ? THR A 510 GLN A 515 
AA5 2 PHE A 514 ? ASN A 518 ? PHE A 520 ASN A 524 
AA5 3 VAL A 529 ? LEU A 538 ? VAL A 535 LEU A 544 
AA5 4 LEU A 543 ? LEU A 551 ? LEU A 549 LEU A 557 
AA5 5 THR A 628 ? LYS A 636 ? THR A 634 LYS A 642 
AA5 6 GLN A 583 ? GLU A 588 ? GLN A 589 GLU A 594 
AA5 7 LYS A 575 ? VAL A 580 ? LYS A 581 VAL A 586 
AA5 8 LYS A 567 ? ASP A 569 ? LYS A 573 ASP A 575 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLY A 330 ? N GLY A 336 O TRP A 333 ? O TRP A 339 
AA2 1 2 N TYR A 412 ? N TYR A 418 O PHE A 417 ? O PHE A 423 
AA2 2 3 N LEU A 420 ? N LEU A 426 O LEU A 428 ? O LEU A 434 
AA2 3 4 N ALA A 429 ? N ALA A 435 O SER A 448 ? O SER A 454 
AA2 4 5 N VAL A 451 ? N VAL A 457 O ILE A 454 ? O ILE A 460 
AA3 1 2 N ASN A 435 ? N ASN A 441 O GLY A 498 ? O GLY A 504 
AA4 1 2 N MET A 489 ? N MET A 495 O GLN A 559 ? O GLN A 565 
AA4 2 3 N VAL A 560 ? N VAL A 566 O LEU A 620 ? O LEU A 626 
AA4 3 4 O ILE A 615 ? O ILE A 621 N ILE A 600 ? N ILE A 606 
AA5 1 2 N THR A 504 ? N THR A 510 O ASN A 518 ? O ASN A 524 
AA5 2 3 N PHE A 515 ? N PHE A 521 O TYR A 536 ? O TYR A 542 
AA5 3 4 N ASN A 530 ? N ASN A 536 O SER A 550 ? O SER A 556 
AA5 4 5 N ASP A 547 ? N ASP A 553 O TYR A 631 ? O TYR A 637 
AA5 5 6 O VAL A 634 ? O VAL A 640 N GLU A 588 ? N GLU A 594 
AA5 6 7 O LEU A 587 ? O LEU A 593 N VAL A 576 ? N VAL A 582 
AA5 7 8 O ASP A 579 ? O ASP A 585 N LYS A 567 ? N LYS A 573 
# 
_pdbx_entry_details.entry_id                   8R73 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 HG1 A THR 570 ? ? H   A TRP 571 ? ? 1.21 
2 1 HG  A SER 488 ? ? H   A GLN 501 ? ? 1.33 
3 1 HD1 A HIS 447 ? ? ZN  A ZN  701 ? ? 1.36 
4 1 HE2 A HIS 491 ? ? ZN  A ZN  701 ? ? 1.43 
5 1 O   A GLU 479 ? ? HG1 A THR 482 ? ? 1.45 
6 1 O   A GLU 479 ? ? OG1 A THR 482 ? ? 2.19 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CG A MET 82  ? ? SD A MET 82  ? ? CE  A MET 82  ? ? 111.12 100.20 10.92  1.60 N 
2 1 N  A ARG 115 ? ? CA A ARG 115 ? ? CB  A ARG 115 ? ? 99.62  110.60 -10.98 1.80 N 
3 1 NE A ARG 392 ? ? CZ A ARG 392 ? ? NH1 A ARG 392 ? ? 123.39 120.30 3.09   0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER A 101 ? ? -148.11 -3.03   
2  1 ASP A 199 ? ? -167.18 115.99  
3  1 ILE A 214 ? ? -124.75 -55.78  
4  1 ALA A 296 ? ? -104.50 -84.55  
5  1 ALA A 344 ? ? 63.43   -168.19 
6  1 LEU A 386 ? ? -87.61  -94.91  
7  1 ASN A 441 ? ? -94.93  48.37   
8  1 ASN A 442 ? ? -148.20 40.17   
9  1 ASP A 449 ? ? -153.68 32.70   
10 1 THR A 459 ? ? 76.13   -7.51   
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   ASN 
_pdbx_validate_peptide_omega.auth_asym_id_1   A 
_pdbx_validate_peptide_omega.auth_seq_id_1    446 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   HIS 
_pdbx_validate_peptide_omega.auth_asym_id_2   A 
_pdbx_validate_peptide_omega.auth_seq_id_2    447 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            146.80 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 104 ? ? 0.101 'SIDE CHAIN' 
2 1 ARG A 115 ? ? 0.108 'SIDE CHAIN' 
3 1 ARG A 158 ? ? 0.209 'SIDE CHAIN' 
4 1 ARG A 381 ? ? 0.124 'SIDE CHAIN' 
5 1 ARG A 632 ? ? 0.104 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 A HOH 917  ? C HOH . 
2 1 A HOH 1093 ? C HOH . 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      A 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       1112 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.77 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 7  ? A MET 1  
2  1 Y 1 A GLY 8  ? A GLY 2  
3  1 Y 1 A SER 9  ? A SER 3  
4  1 Y 1 A SER 10 ? A SER 4  
5  1 Y 1 A HIS 11 ? A HIS 5  
6  1 Y 1 A HIS 12 ? A HIS 6  
7  1 Y 1 A HIS 13 ? A HIS 7  
8  1 Y 1 A HIS 14 ? A HIS 8  
9  1 Y 1 A HIS 15 ? A HIS 9  
10 1 Y 1 A HIS 16 ? A HIS 10 
11 1 Y 1 A SER 17 ? A SER 11 
12 1 Y 1 A SER 18 ? A SER 12 
13 1 Y 1 A GLY 19 ? A GLY 13 
14 1 Y 1 A PRO 20 ? A PRO 14 
15 1 Y 1 A GLN 21 ? A GLN 15 
16 1 Y 1 A GLN 22 ? A GLN 16 
17 1 Y 1 A GLY 23 ? A GLY 17 
18 1 Y 1 A LEU 24 ? A LEU 18 
19 1 Y 1 A ARG 25 ? A ARG 19 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
HOH O    O  N N 158 
HOH H1   H  N N 159 
HOH H2   H  N N 160 
ILE N    N  N N 161 
ILE CA   C  N S 162 
ILE C    C  N N 163 
ILE O    O  N N 164 
ILE CB   C  N S 165 
ILE CG1  C  N N 166 
ILE CG2  C  N N 167 
ILE CD1  C  N N 168 
ILE OXT  O  N N 169 
ILE H    H  N N 170 
ILE H2   H  N N 171 
ILE HA   H  N N 172 
ILE HB   H  N N 173 
ILE HG12 H  N N 174 
ILE HG13 H  N N 175 
ILE HG21 H  N N 176 
ILE HG22 H  N N 177 
ILE HG23 H  N N 178 
ILE HD11 H  N N 179 
ILE HD12 H  N N 180 
ILE HD13 H  N N 181 
ILE HXT  H  N N 182 
LEU N    N  N N 183 
LEU CA   C  N S 184 
LEU C    C  N N 185 
LEU O    O  N N 186 
LEU CB   C  N N 187 
LEU CG   C  N N 188 
LEU CD1  C  N N 189 
LEU CD2  C  N N 190 
LEU OXT  O  N N 191 
LEU H    H  N N 192 
LEU H2   H  N N 193 
LEU HA   H  N N 194 
LEU HB2  H  N N 195 
LEU HB3  H  N N 196 
LEU HG   H  N N 197 
LEU HD11 H  N N 198 
LEU HD12 H  N N 199 
LEU HD13 H  N N 200 
LEU HD21 H  N N 201 
LEU HD22 H  N N 202 
LEU HD23 H  N N 203 
LEU HXT  H  N N 204 
LYS N    N  N N 205 
LYS CA   C  N S 206 
LYS C    C  N N 207 
LYS O    O  N N 208 
LYS CB   C  N N 209 
LYS CG   C  N N 210 
LYS CD   C  N N 211 
LYS CE   C  N N 212 
LYS NZ   N  N N 213 
LYS OXT  O  N N 214 
LYS H    H  N N 215 
LYS H2   H  N N 216 
LYS HA   H  N N 217 
LYS HB2  H  N N 218 
LYS HB3  H  N N 219 
LYS HG2  H  N N 220 
LYS HG3  H  N N 221 
LYS HD2  H  N N 222 
LYS HD3  H  N N 223 
LYS HE2  H  N N 224 
LYS HE3  H  N N 225 
LYS HZ1  H  N N 226 
LYS HZ2  H  N N 227 
LYS HZ3  H  N N 228 
LYS HXT  H  N N 229 
MET N    N  N N 230 
MET CA   C  N S 231 
MET C    C  N N 232 
MET O    O  N N 233 
MET CB   C  N N 234 
MET CG   C  N N 235 
MET SD   S  N N 236 
MET CE   C  N N 237 
MET OXT  O  N N 238 
MET H    H  N N 239 
MET H2   H  N N 240 
MET HA   H  N N 241 
MET HB2  H  N N 242 
MET HB3  H  N N 243 
MET HG2  H  N N 244 
MET HG3  H  N N 245 
MET HE1  H  N N 246 
MET HE2  H  N N 247 
MET HE3  H  N N 248 
MET HXT  H  N N 249 
PHE N    N  N N 250 
PHE CA   C  N S 251 
PHE C    C  N N 252 
PHE O    O  N N 253 
PHE CB   C  N N 254 
PHE CG   C  Y N 255 
PHE CD1  C  Y N 256 
PHE CD2  C  Y N 257 
PHE CE1  C  Y N 258 
PHE CE2  C  Y N 259 
PHE CZ   C  Y N 260 
PHE OXT  O  N N 261 
PHE H    H  N N 262 
PHE H2   H  N N 263 
PHE HA   H  N N 264 
PHE HB2  H  N N 265 
PHE HB3  H  N N 266 
PHE HD1  H  N N 267 
PHE HD2  H  N N 268 
PHE HE1  H  N N 269 
PHE HE2  H  N N 270 
PHE HZ   H  N N 271 
PHE HXT  H  N N 272 
PRO N    N  N N 273 
PRO CA   C  N S 274 
PRO C    C  N N 275 
PRO O    O  N N 276 
PRO CB   C  N N 277 
PRO CG   C  N N 278 
PRO CD   C  N N 279 
PRO OXT  O  N N 280 
PRO H    H  N N 281 
PRO HA   H  N N 282 
PRO HB2  H  N N 283 
PRO HB3  H  N N 284 
PRO HG2  H  N N 285 
PRO HG3  H  N N 286 
PRO HD2  H  N N 287 
PRO HD3  H  N N 288 
PRO HXT  H  N N 289 
SER N    N  N N 290 
SER CA   C  N S 291 
SER C    C  N N 292 
SER O    O  N N 293 
SER CB   C  N N 294 
SER OG   O  N N 295 
SER OXT  O  N N 296 
SER H    H  N N 297 
SER H2   H  N N 298 
SER HA   H  N N 299 
SER HB2  H  N N 300 
SER HB3  H  N N 301 
SER HG   H  N N 302 
SER HXT  H  N N 303 
THR N    N  N N 304 
THR CA   C  N S 305 
THR C    C  N N 306 
THR O    O  N N 307 
THR CB   C  N R 308 
THR OG1  O  N N 309 
THR CG2  C  N N 310 
THR OXT  O  N N 311 
THR H    H  N N 312 
THR H2   H  N N 313 
THR HA   H  N N 314 
THR HB   H  N N 315 
THR HG1  H  N N 316 
THR HG21 H  N N 317 
THR HG22 H  N N 318 
THR HG23 H  N N 319 
THR HXT  H  N N 320 
TRP N    N  N N 321 
TRP CA   C  N S 322 
TRP C    C  N N 323 
TRP O    O  N N 324 
TRP CB   C  N N 325 
TRP CG   C  Y N 326 
TRP CD1  C  Y N 327 
TRP CD2  C  Y N 328 
TRP NE1  N  Y N 329 
TRP CE2  C  Y N 330 
TRP CE3  C  Y N 331 
TRP CZ2  C  Y N 332 
TRP CZ3  C  Y N 333 
TRP CH2  C  Y N 334 
TRP OXT  O  N N 335 
TRP H    H  N N 336 
TRP H2   H  N N 337 
TRP HA   H  N N 338 
TRP HB2  H  N N 339 
TRP HB3  H  N N 340 
TRP HD1  H  N N 341 
TRP HE1  H  N N 342 
TRP HE3  H  N N 343 
TRP HZ2  H  N N 344 
TRP HZ3  H  N N 345 
TRP HH2  H  N N 346 
TRP HXT  H  N N 347 
TYR N    N  N N 348 
TYR CA   C  N S 349 
TYR C    C  N N 350 
TYR O    O  N N 351 
TYR CB   C  N N 352 
TYR CG   C  Y N 353 
TYR CD1  C  Y N 354 
TYR CD2  C  Y N 355 
TYR CE1  C  Y N 356 
TYR CE2  C  Y N 357 
TYR CZ   C  Y N 358 
TYR OH   O  N N 359 
TYR OXT  O  N N 360 
TYR H    H  N N 361 
TYR H2   H  N N 362 
TYR HA   H  N N 363 
TYR HB2  H  N N 364 
TYR HB3  H  N N 365 
TYR HD1  H  N N 366 
TYR HD2  H  N N 367 
TYR HE1  H  N N 368 
TYR HE2  H  N N 369 
TYR HH   H  N N 370 
TYR HXT  H  N N 371 
VAL N    N  N N 372 
VAL CA   C  N S 373 
VAL C    C  N N 374 
VAL O    O  N N 375 
VAL CB   C  N N 376 
VAL CG1  C  N N 377 
VAL CG2  C  N N 378 
VAL OXT  O  N N 379 
VAL H    H  N N 380 
VAL H2   H  N N 381 
VAL HA   H  N N 382 
VAL HB   H  N N 383 
VAL HG11 H  N N 384 
VAL HG12 H  N N 385 
VAL HG13 H  N N 386 
VAL HG21 H  N N 387 
VAL HG22 H  N N 388 
VAL HG23 H  N N 389 
VAL HXT  H  N N 390 
ZN  ZN   ZN N N 391 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Royal Society'  'United Kingdom' 212050     1 
'Wellcome Trust' 'United Kingdom' 1065163470 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8R73 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009650 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.003376 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010942 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012498 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C  6  6  2.3103  20.8439 1.0201 10.2075 1.5888 0.5687  0.8651 51.6512 0.2156   
H  1  1  0.4930  10.5109 0.3229 26.1257 0.1402 3.1424  0.0408 57.7997 0.0030   
N  7  7  12.2220 0.0057  3.1346 9.8933  2.0141 28.9975 1.1672 0.5826  -11.5379 
O  8  8  3.0487  13.2771 2.2870 5.7011  1.5464 0.3239  0.8671 32.9089 0.2508   
S  16 16 6.9054  1.4679  5.2035 22.2151 1.4379 0.2536  1.5863 56.1720 1.0487   
ZN 30 30 14.0812 3.2655  7.0352 0.2333  5.1677 10.3163 2.4112 58.7097 1.0032   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1     N  N    . TYR A 1 20  ? 13.847  -15.726 19.628  1   60.969  ? 26   TYR A N    1 ? 
ATOM   2     C  CA   . TYR A 1 20  ? 14.306  -16.703 18.601  1   61.045  ? 26   TYR A CA   1 ? 
ATOM   3     C  C    . TYR A 1 20  ? 13.164  -17.66  18.262  1   67.422  ? 26   TYR A C    1 ? 
ATOM   4     O  O    . TYR A 1 20  ? 12.575  -18.254 19.166  1   65.283  ? 26   TYR A O    1 ? 
ATOM   5     C  CB   . TYR A 1 20  ? 15.518  -17.558 18.997  1   63.618  ? 26   TYR A CB   1 ? 
ATOM   6     C  CG   . TYR A 1 20  ? 16.202  -18.213 17.799  1   62.556  ? 26   TYR A CG   1 ? 
ATOM   7     C  CD1  . TYR A 1 20  ? 17.153  -17.517 17.044  1   64.235  ? 26   TYR A CD1  1 ? 
ATOM   8     C  CD2  . TYR A 1 20  ? 15.889  -19.511 17.41   1   58.862  ? 26   TYR A CD2  1 ? 
ATOM   9     C  CE1  . TYR A 1 20  ? 17.765  -18.091 15.937  1   65.197  ? 26   TYR A CE1  1 ? 
ATOM   10    C  CE2  . TYR A 1 20  ? 16.513  -20.102 16.318  1   62.555  ? 26   TYR A CE2  1 ? 
ATOM   11    C  CZ   . TYR A 1 20  ? 17.442  -19.388 15.576  1   61.866  ? 26   TYR A CZ   1 ? 
ATOM   12    O  OH   . TYR A 1 20  ? 18.039  -19.982 14.515  1   59.212  ? 26   TYR A OH   1 ? 
ATOM   13    H  H    . TYR A 1 20  ? 14.528  -15.18  19.854  1   61.009  ? 26   TYR A H    1 c 
ATOM   14    H  HA   . TYR A 1 20  ? 14.543  -16.194 17.781  1   62.711  ? 26   TYR A HA   1 c 
ATOM   15    H  HB2  . TYR A 1 20  ? 16.167  -16.987 19.464  1   62.793  ? 26   TYR A HB2  1 c 
ATOM   16    H  HB3  . TYR A 1 20  ? 15.221  -18.259 19.62   1   62.824  ? 26   TYR A HB3  1 c 
ATOM   17    H  HD1  . TYR A 1 20  ? 17.371  -16.63  17.28   1   64.003  ? 26   TYR A HD1  1 c 
ATOM   18    H  HD2  . TYR A 1 20  ? 15.255  -20.005 17.904  1   60.618  ? 26   TYR A HD2  1 c 
ATOM   19    H  HE1  . TYR A 1 20  ? 18.407  -17.608 15.444  1   64.108  ? 26   TYR A HE1  1 c 
ATOM   20    H  HE2  . TYR A 1 20  ? 16.291  -20.981 16.068  1   61.55   ? 26   TYR A HE2  1 c 
ATOM   21    H  HH   . TYR A 1 20  ? 18.808  -20.362 14.657  0   57.73   ? 26   TYR A HH   1 c 
ATOM   22    N  N    . THR A 1 21  ? 12.929  -17.827 16.946  1   70.169  ? 27   THR A N    1 ? 
ATOM   23    C  CA   . THR A 1 21  ? 11.863  -18.646 16.376  1   66.107  ? 27   THR A CA   1 ? 
ATOM   24    C  C    . THR A 1 21  ? 12.439  -19.418 15.192  1   62.425  ? 27   THR A C    1 ? 
ATOM   25    O  O    . THR A 1 21  ? 13.11   -18.824 14.354  1   47.807  ? 27   THR A O    1 ? 
ATOM   26    C  CB   . THR A 1 21  ? 10.711  -17.759 15.893  1   60.201  ? 27   THR A CB   1 ? 
ATOM   27    O  OG1  . THR A 1 21  ? 10.457  -16.825 16.939  1   54.144  ? 27   THR A OG1  1 ? 
ATOM   28    C  CG2  . THR A 1 21  ? 9.497   -18.559 15.45   1   56.216  ? 27   THR A CG2  1 ? 
ATOM   29    H  H    . THR A 1 21  ? 13.482  -17.393 16.361  1   68.417  ? 27   THR A H    1 c 
ATOM   30    H  HA   . THR A 1 21  ? 11.534  -19.274 17.055  1   65.012  ? 27   THR A HA   1 c 
ATOM   31    H  HB   . THR A 1 21  ? 11.025  -17.257 15.103  1   59.184  ? 27   THR A HB   1 c 
ATOM   32    H  HG1  . THR A 1 21  ? 10.145  -17.554 17.76   0   56.75   ? 27   THR A HG1  1 c 
ATOM   33    H  HG21 . THR A 1 21  ? 8.753   -17.956 15.286  1   57.371  ? 27   THR A HG21 1 c 
ATOM   34    H  HG22 . THR A 1 21  ? 9.253   -19.191 16.148  1   57.371  ? 27   THR A HG22 1 c 
ATOM   35    H  HG23 . THR A 1 21  ? 9.706   -19.044 14.634  1   57.388  ? 27   THR A HG23 1 c 
ATOM   36    N  N    . GLU A 1 22  ? 12.112  -20.715 15.096  1   59.789  ? 28   GLU A N    1 ? 
ATOM   37    C  CA   . GLU A 1 22  ? 12.668  -21.577 14.061  1   58.573  ? 28   GLU A CA   1 ? 
ATOM   38    C  C    . GLU A 1 22  ? 11.858  -21.444 12.763  1   53.567  ? 28   GLU A C    1 ? 
ATOM   39    O  O    . GLU A 1 22  ? 11.145  -22.352 12.371  1   52.223  ? 28   GLU A O    1 ? 
ATOM   40    C  CB   . GLU A 1 22  ? 12.742  -22.957 14.718  1   60.961  ? 28   GLU A CB   1 ? 
ATOM   41    C  CG   . GLU A 1 22  ? 13.773  -23.917 14.138  1   70.894  ? 28   GLU A CG   1 ? 
ATOM   42    C  CD   . GLU A 1 22  ? 15.26   -23.648 14.332  1   69.876  ? 28   GLU A CD   1 ? 
ATOM   43    O  OE1  . GLU A 1 22  ? 15.964  -23.875 13.325  1   59.077  ? 28   GLU A OE1  1 ? 
ATOM   44    O  OE2  . GLU A 1 22  ? 15.727  -23.263 15.42   1   62.781  ? 28   GLU A OE2  1 ? 
ATOM   45    H  H    . GLU A 1 22  ? 11.517  -21.07  15.693  1   60.231  ? 28   GLU A H    1 c 
ATOM   46    H  HA   . GLU A 1 22  ? 13.595  -21.28  13.877  1   58.286  ? 28   GLU A HA   1 c 
ATOM   47    H  HB2  . GLU A 1 22  ? 12.967  -22.841 15.663  1   62.484  ? 28   GLU A HB2  1 c 
ATOM   48    H  HB3  . GLU A 1 22  ? 11.858  -23.377 14.672  1   62.463  ? 28   GLU A HB3  1 c 
ATOM   49    H  HG2  . GLU A 1 22  ? 13.589  -24.81  14.501  1   68.183  ? 28   GLU A HG2  1 c 
ATOM   50    H  HG3  . GLU A 1 22  ? 13.609  -23.982 13.175  1   67.883  ? 28   GLU A HG3  1 c 
ATOM   51    N  N    . ARG A 1 23  ? 12.008  -20.324 12.044  1   42.684  ? 29   ARG A N    1 ? 
ATOM   52    C  CA   . ARG A 1 23  ? 11.276  -20.129 10.799  1   43.048  ? 29   ARG A CA   1 ? 
ATOM   53    C  C    . ARG A 1 23  ? 11.934  -20.873 9.628   1   41.439  ? 29   ARG A C    1 ? 
ATOM   54    O  O    . ARG A 1 23  ? 11.276  -21.566 8.827   1   42.216  ? 29   ARG A O    1 ? 
ATOM   55    C  CB   . ARG A 1 23  ? 11.189  -18.633 10.511  1   39.71   ? 29   ARG A CB   1 ? 
ATOM   56    C  CG   . ARG A 1 23  ? 10.658  -17.833 11.693  1   41.647  ? 29   ARG A CG   1 ? 
ATOM   57    C  CD   . ARG A 1 23  ? 10.41   -16.359 11.41   1   45.04   ? 29   ARG A CD   1 ? 
ATOM   58    N  NE   . ARG A 1 23  ? 9.76    -15.673 12.537  1   45.666  ? 29   ARG A NE   1 ? 
ATOM   59    C  CZ   . ARG A 1 23  ? 10.24   -14.665 13.268  1   43.086  ? 29   ARG A CZ   1 ? 
ATOM   60    N  NH1  . ARG A 1 23  ? 11.433  -14.147 13.063  1   45.364  ? 29   ARG A NH1  1 ? 
ATOM   61    N  NH2  . ARG A 1 23  ? 9.516   -14.173 14.252  1   50.583  ? 29   ARG A NH2  1 ? 
ATOM   62    H  H    . ARG A 1 23  ? 12.592  -19.68  12.325  1   45.171  ? 29   ARG A H    1 c 
ATOM   63    H  HA   . ARG A 1 23  ? 10.356  -20.477 10.918  1   42.161  ? 29   ARG A HA   1 c 
ATOM   64    H  HB2  . ARG A 1 23  ? 12.08   -18.298 10.274  1   40.875  ? 29   ARG A HB2  1 c 
ATOM   65    H  HB3  . ARG A 1 23  ? 10.6    -18.49  9.74    1   40.885  ? 29   ARG A HB3  1 c 
ATOM   66    H  HG2  . ARG A 1 23  ? 9.816   -18.239 11.994  1   41.947  ? 29   ARG A HG2  1 c 
ATOM   67    H  HG3  . ARG A 1 23  ? 11.294  -17.903 12.436  1   41.972  ? 29   ARG A HG3  1 c 
ATOM   68    H  HD2  . ARG A 1 23  ? 11.263  -15.925 11.211  1   44.394  ? 29   ARG A HD2  1 c 
ATOM   69    H  HD3  . ARG A 1 23  ? 9.843   -16.279 10.617  1   44.394  ? 29   ARG A HD3  1 c 
ATOM   70    H  HE   . ARG A 1 23  ? 8.965   -15.956 12.755  1   44.965  ? 29   ARG A HE   1 c 
ATOM   71    H  HH11 . ARG A 1 23  ? 12.012  -14.548 12.528  1   44.667  ? 29   ARG A HH11 1 c 
ATOM   72    H  HH12 . ARG A 1 23  ? 11.658  -13.392 13.467  1   44.723  ? 29   ARG A HH12 1 c 
ATOM   73    H  HH21 . ARG A 1 23  ? 8.846   -14.646 14.587  1   48.084  ? 29   ARG A HH21 1 c 
ATOM   74    H  HH22 . ARG A 1 23  ? 9.699   -13.371 14.579  1   48.08   ? 29   ARG A HH22 1 c 
ATOM   75    N  N    . ASN A 1 24  ? 13.224  -20.634 9.469   1   39.232  ? 30   ASN A N    1 ? 
ATOM   76    C  CA   . ASN A 1 24  ? 14.026  -21.259 8.433   1   42.463  ? 30   ASN A CA   1 ? 
ATOM   77    C  C    . ASN A 1 24  ? 13.433  -20.996 7.057   1   38.084  ? 30   ASN A C    1 ? 
ATOM   78    O  O    . ASN A 1 24  ? 13.272  -21.921 6.257   1   40.501  ? 30   ASN A O    1 ? 
ATOM   79    C  CB   . ASN A 1 24  ? 14.215  -22.736 8.754   1   45.631  ? 30   ASN A CB   1 ? 
ATOM   80    C  CG   . ASN A 1 24  ? 15.028  -22.891 10.017  1   47.657  ? 30   ASN A CG   1 ? 
ATOM   81    O  OD1  . ASN A 1 24  ? 16.019  -22.181 10.209  1   50.899  ? 30   ASN A OD1  1 ? 
ATOM   82    N  ND2  . ASN A 1 24  ? 14.615  -23.775 10.907  1   56.683  ? 30   ASN A ND2  1 ? 
ATOM   83    H  H    . ASN A 1 24  ? 13.635  -20.045 10.036  1   40.478  ? 30   ASN A H    1 c 
ATOM   84    H  HA   . ASN A 1 24  ? 14.916  -20.842 8.455   1   41.595  ? 30   ASN A HA   1 c 
ATOM   85    H  HB2  . ASN A 1 24  ? 13.344  -23.164 8.868   1   45.417  ? 30   ASN A HB2  1 c 
ATOM   86    H  HB3  . ASN A 1 24  ? 14.68   -23.175 8.014   1   45.33   ? 30   ASN A HB3  1 c 
ATOM   87    H  HD21 . ASN A 1 24  ? 15.197  -24.137 11.47   1   53.889  ? 30   ASN A HD21 1 c 
ATOM   88    H  HD22 . ASN A 1 24  ? 13.76   -24.011 10.936  1   53.746  ? 30   ASN A HD22 1 c 
ATOM   89    N  N    . LEU A 1 25  ? 13.105  -19.725 6.796   1   38.857  ? 31   LEU A N    1 ? 
ATOM   90    C  CA   . LEU A 1 25  ? 12.323  -19.391 5.614   1   38.036  ? 31   LEU A CA   1 ? 
ATOM   91    C  C    . LEU A 1 25  ? 13.114  -19.702 4.354   1   38.316  ? 31   LEU A C    1 ? 
ATOM   92    O  O    . LEU A 1 25  ? 12.545  -20.155 3.375   1   35.324  ? 31   LEU A O    1 ? 
ATOM   93    C  CB   . LEU A 1 25  ? 11.86   -17.936 5.63    1   40.16   ? 31   LEU A CB   1 ? 
ATOM   94    C  CG   . LEU A 1 25  ? 10.921  -17.576 6.792   1   41.964  ? 31   LEU A CG   1 ? 
ATOM   95    C  CD1  . LEU A 1 25  ? 10.483  -16.134 6.711   1   38.444  ? 31   LEU A CD1  1 ? 
ATOM   96    C  CD2  . LEU A 1 25  ? 9.715   -18.524 6.854   1   39.59   ? 31   LEU A CD2  1 ? 
ATOM   97    H  H    . LEU A 1 25  ? 13.375  -19.056 7.357   1   38.541  ? 31   LEU A H    1 c 
ATOM   98    H  HA   . LEU A 1 25  ? 11.524  -19.975 5.61    1   38.628  ? 31   LEU A HA   1 c 
ATOM   99    H  HB2  . LEU A 1 25  ? 12.657  -17.358 5.681   1   40.059  ? 31   LEU A HB2  1 c 
ATOM   100   H  HB3  . LEU A 1 25  ? 11.396  -17.748 4.782   1   40.051  ? 31   LEU A HB3  1 c 
ATOM   101   H  HG   . LEU A 1 25  ? 11.43   -17.686 7.637   1   40.492  ? 31   LEU A HG   1 c 
ATOM   102   H  HD11 . LEU A 1 25  ? 11.263  -15.554 6.748   1   39.459  ? 31   LEU A HD11 1 c 
ATOM   103   H  HD12 . LEU A 1 25  ? 9.894   -15.93  7.456   1   39.463  ? 31   LEU A HD12 1 c 
ATOM   104   H  HD13 . LEU A 1 25  ? 10.01   -15.984 5.875   1   39.459  ? 31   LEU A HD13 1 c 
ATOM   105   H  HD21 . LEU A 1 25  ? 10      -19.395 7.179   1   40.244  ? 31   LEU A HD21 1 c 
ATOM   106   H  HD22 . LEU A 1 25  ? 9.331   -18.62  5.966   1   40.263  ? 31   LEU A HD22 1 c 
ATOM   107   H  HD23 . LEU A 1 25  ? 9.046   -18.158 7.457   1   40.259  ? 31   LEU A HD23 1 c 
ATOM   108   N  N    . LEU A 1 26  ? 14.414  -19.399 4.359   1   36.959  ? 32   LEU A N    1 ? 
ATOM   109   C  CA   . LEU A 1 26  ? 15.199  -19.569 3.151   1   40.917  ? 32   LEU A CA   1 ? 
ATOM   110   C  C    . LEU A 1 26  ? 15.274  -21.052 2.783   1   34.321  ? 32   LEU A C    1 ? 
ATOM   111   O  O    . LEU A 1 26  ? 15.03   -21.401 1.633   1   37.672  ? 32   LEU A O    1 ? 
ATOM   112   C  CB   . LEU A 1 26  ? 16.578  -18.925 3.299   1   37.697  ? 32   LEU A CB   1 ? 
ATOM   113   C  CG   . LEU A 1 26  ? 16.598  -17.39  3.278   1   34.994  ? 32   LEU A CG   1 ? 
ATOM   114   C  CD1  . LEU A 1 26  ? 17.943  -16.799 3.672   1   34.383  ? 32   LEU A CD1  1 ? 
ATOM   115   C  CD2  . LEU A 1 26  ? 16.222  -16.941 1.899   1   35.401  ? 32   LEU A CD2  1 ? 
ATOM   116   H  H    . LEU A 1 26  ? 14.81   -19.065 5.112   1   38.134  ? 32   LEU A H    1 c 
ATOM   117   H  HA   . LEU A 1 26  ? 14.717  -19.11  2.418   1   38.199  ? 32   LEU A HA   1 c 
ATOM   118   H  HB2  . LEU A 1 26  ? 16.976  -19.232 4.144   1   37.744  ? 32   LEU A HB2  1 c 
ATOM   119   H  HB3  . LEU A 1 26  ? 17.151  -19.254 2.569   1   37.708  ? 32   LEU A HB3  1 c 
ATOM   120   H  HG   . LEU A 1 26  ? 15.911  -17.059 3.913   1   35.436  ? 32   LEU A HG   1 c 
ATOM   121   H  HD11 . LEU A 1 26  ? 18.17   -17.08  4.574   1   34.563  ? 32   LEU A HD11 1 c 
ATOM   122   H  HD12 . LEU A 1 26  ? 17.894  -15.829 3.639   1   34.567  ? 32   LEU A HD12 1 c 
ATOM   123   H  HD13 . LEU A 1 26  ? 18.627  -17.109 3.055   1   34.563  ? 32   LEU A HD13 1 c 
ATOM   124   H  HD21 . LEU A 1 26  ? 15.282  -17.126 1.739   1   35.33   ? 32   LEU A HD21 1 c 
ATOM   125   H  HD22 . LEU A 1 26  ? 16.761  -17.415 1.243   1   35.316  ? 32   LEU A HD22 1 c 
ATOM   126   H  HD23 . LEU A 1 26  ? 16.38   -15.986 1.815   1   35.279  ? 32   LEU A HD23 1 c 
ATOM   127   N  N    . GLN A 1 27  ? 15.664  -21.891 3.74    1   38.371  ? 33   GLN A N    1 ? 
ATOM   128   C  CA   . GLN A 1 27  ? 15.782  -23.332 3.538   1   43.555  ? 33   GLN A CA   1 ? 
ATOM   129   C  C    . GLN A 1 27  ? 14.444  -23.956 3.111   1   39.634  ? 33   GLN A C    1 ? 
ATOM   130   O  O    . GLN A 1 27  ? 14.438  -24.849 2.291   1   39.199  ? 33   GLN A O    1 ? 
ATOM   131   C  CB   . GLN A 1 27  ? 16.301  -23.984 4.822   1   48.697  ? 33   GLN A CB   1 ? 
ATOM   132   C  CG   . GLN A 1 27  ? 17.783  -23.745 5.094   1   52.242  ? 33   GLN A CG   1 ? 
ATOM   133   C  CD   . GLN A 1 27  ? 18.19   -24.027 6.524   1   49.667  ? 33   GLN A CD   1 ? 
ATOM   134   O  OE1  . GLN A 1 27  ? 18.776  -25.074 6.822   1   51.891  ? 33   GLN A OE1  1 ? 
ATOM   135   N  NE2  . GLN A 1 27  ? 17.909  -23.086 7.42    1   44.022  ? 33   GLN A NE2  1 ? 
ATOM   136   H  H    . GLN A 1 27  ? 15.873  -21.55  4.561   1   38.585  ? 33   GLN A H    1 c 
ATOM   137   H  HA   . GLN A 1 27  ? 16.444  -23.488 2.818   1   42.63   ? 33   GLN A HA   1 c 
ATOM   138   H  HB2  . GLN A 1 27  ? 15.781  -23.642 5.579   1   48.166  ? 33   GLN A HB2  1 c 
ATOM   139   H  HB3  . GLN A 1 27  ? 16.143  -24.95  4.767   1   48.176  ? 33   GLN A HB3  1 c 
ATOM   140   H  HG2  . GLN A 1 27  ? 18.315  -24.314 4.5     1   50.696  ? 33   GLN A HG2  1 c 
ATOM   141   H  HG3  . GLN A 1 27  ? 18.001  -22.812 4.885   1   50.765  ? 33   GLN A HG3  1 c 
ATOM   142   H  HE21 . GLN A 1 27  ? 18.153  -23.194 8.266   1   45.752  ? 33   GLN A HE21 1 c 
ATOM   143   H  HE22 . GLN A 1 27  ? 17.479  -22.351 7.172   1   45.78   ? 33   GLN A HE22 1 c 
ATOM   144   N  N    . LYS A 1 28  ? 13.3    -23.445 3.59    1   41.3    ? 34   LYS A N    1 ? 
ATOM   145   C  CA   . LYS A 1 28  ? 12.004  -23.975 3.192   1   43.657  ? 34   LYS A CA   1 ? 
ATOM   146   C  C    . LYS A 1 28  ? 11.66   -23.564 1.769   1   47.784  ? 34   LYS A C    1 ? 
ATOM   147   O  O    . LYS A 1 28  ? 11.033  -24.333 1.057   1   42.733  ? 34   LYS A O    1 ? 
ATOM   148   C  CB   . LYS A 1 28  ? 10.84   -23.517 4.069   1   44.468  ? 34   LYS A CB   1 ? 
ATOM   149   C  CG   . LYS A 1 28  ? 10.84   -24.207 5.387   1   43.489  ? 34   LYS A CG   1 ? 
ATOM   150   C  CD   . LYS A 1 28  ? 9.94    -23.567 6.429   1   44.377  ? 34   LYS A CD   1 ? 
ATOM   151   C  CE   . LYS A 1 28  ? 10.364  -24.12  7.768   1   50.532  ? 34   LYS A CE   1 ? 
ATOM   152   N  NZ   . LYS A 1 28  ? 9.254   -24.188 8.72    1   54.59   ? 34   LYS A NZ   1 ? 
ATOM   153   H  H    . LYS A 1 28  ? 13.329  -22.752 4.185   1   41.35   ? 34   LYS A H    1 c 
ATOM   154   H  HA   . LYS A 1 28  ? 12.049  -24.965 3.23    1   44.004  ? 34   LYS A HA   1 c 
ATOM   155   H  HB2  . LYS A 1 28  ? 10.903  -22.549 4.215   1   44.068  ? 34   LYS A HB2  1 c 
ATOM   156   H  HB3  . LYS A 1 28  ? 9.991   -23.704 3.613   1   44.078  ? 34   LYS A HB3  1 c 
ATOM   157   H  HG2  . LYS A 1 28  ? 10.557  -25.137 5.251   1   43.928  ? 34   LYS A HG2  1 c 
ATOM   158   H  HG3  . LYS A 1 28  ? 11.761  -24.222 5.728   1   43.975  ? 34   LYS A HG3  1 c 
ATOM   159   H  HD2  . LYS A 1 28  ? 10.05   -22.591 6.423   1   45.507  ? 34   LYS A HD2  1 c 
ATOM   160   H  HD3  . LYS A 1 28  ? 9.001   -23.797 6.256   1   45.552  ? 34   LYS A HD3  1 c 
ATOM   161   H  HE2  . LYS A 1 28  ? 10.715  -25.022 7.646   1   49.876  ? 34   LYS A HE2  1 c 
ATOM   162   H  HE3  . LYS A 1 28  ? 11.078  -23.578 8.142   1   49.893  ? 34   LYS A HE3  1 c 
ATOM   163   H  HZ1  . LYS A 1 28  ? 8.611   -24.742 8.404   1   53.251  ? 34   LYS A HZ1  1 c 
ATOM   164   H  HZ2  . LYS A 1 28  ? 8.902   -23.361 8.84    1   53.294  ? 34   LYS A HZ2  1 c 
ATOM   165   H  HZ3  . LYS A 1 28  ? 9.552   -24.502 9.516   1   53.294  ? 34   LYS A HZ3  1 c 
ATOM   166   N  N    . ALA A 1 29  ? 12.045  -22.347 1.381   1   44.589  ? 35   ALA A N    1 ? 
ATOM   167   C  CA   . ALA A 1 29  ? 11.747  -21.836 0.056   1   45.428  ? 35   ALA A CA   1 ? 
ATOM   168   C  C    . ALA A 1 29  ? 12.52   -22.589 -1.03   1   44.657  ? 35   ALA A C    1 ? 
ATOM   169   O  O    . ALA A 1 29  ? 11.991  -22.854 -2.109  1   45.516  ? 35   ALA A O    1 ? 
ATOM   170   C  CB   . ALA A 1 29  ? 12.037  -20.344 0.042   1   44.858  ? 35   ALA A CB   1 ? 
ATOM   171   H  H    . ALA A 1 29  ? 12.506  -21.815 1.964   1   45.469  ? 35   ALA A H    1 c 
ATOM   172   H  HA   . ALA A 1 29  ? 10.774  -21.972 -0.113  1   45.02   ? 35   ALA A HA   1 c 
ATOM   173   H  HB1  . ALA A 1 29  ? 11.477  -19.895 0.697   1   45.026  ? 35   ALA A HB1  1 c 
ATOM   174   H  HB2  . ALA A 1 29  ? 12.972  -20.19  0.26    1   45.028  ? 35   ALA A HB2  1 c 
ATOM   175   H  HB3  . ALA A 1 29  ? 11.85   -19.983 -0.841  1   45.026  ? 35   ALA A HB3  1 c 
ATOM   176   N  N    . ALA A 1 30  ? 13.783  -22.923 -0.769  1   45.89   ? 36   ALA A N    1 ? 
ATOM   177   C  CA   . ALA A 1 30  ? 14.593  -23.659 -1.733  1   45.344  ? 36   ALA A CA   1 ? 
ATOM   178   C  C    . ALA A 1 30  ? 14.36   -25.165 -1.637  1   46.999  ? 36   ALA A C    1 ? 
ATOM   179   O  O    . ALA A 1 30  ? 14.514  -25.861 -2.638  1   48.052  ? 36   ALA A O    1 ? 
ATOM   180   C  CB   . ALA A 1 30  ? 16.056  -23.369 -1.525  1   41.705  ? 36   ALA A CB   1 ? 
ATOM   181   H  H    . ALA A 1 30  ? 14.157  -22.685 0.03    1   45.438  ? 36   ALA A H    1 c 
ATOM   182   H  HA   . ALA A 1 30  ? 14.334  -23.364 -2.65   1   45.047  ? 36   ALA A HA   1 c 
ATOM   183   H  HB1  . ALA A 1 30  ? 16.229  -22.428 -1.696  1   42.717  ? 36   ALA A HB1  1 c 
ATOM   184   H  HB2  . ALA A 1 30  ? 16.303  -23.581 -0.61   1   42.701  ? 36   ALA A HB2  1 c 
ATOM   185   H  HB3  . ALA A 1 30  ? 16.587  -23.909 -2.135  1   42.759  ? 36   ALA A HB3  1 c 
ATOM   186   N  N    . GLY A 1 31  ? 14.112  -25.673 -0.42   1   45.563  ? 37   GLY A N    1 ? 
ATOM   187   C  CA   . GLY A 1 31  ? 13.87   -27.095 -0.208  1   45.995  ? 37   GLY A CA   1 ? 
ATOM   188   C  C    . GLY A 1 31  ? 15.124  -27.799 0.325   1   43.93   ? 37   GLY A C    1 ? 
ATOM   189   O  O    . GLY A 1 31  ? 15.113  -28.411 1.384   1   50.614  ? 37   GLY A O    1 ? 
ATOM   190   H  H    . GLY A 1 31  ? 14.099  -25.115 0.304   1   45.994  ? 37   GLY A H    1 c 
ATOM   191   H  HA2  . GLY A 1 31  ? 13.133  -27.203 0.438   1   45.435  ? 37   GLY A HA2  1 c 
ATOM   192   H  HA3  . GLY A 1 31  ? 13.592  -27.51  -1.056  1   45.47   ? 37   GLY A HA3  1 c 
ATOM   193   N  N    . SER A 1 32  ? 16.226  -27.651 -0.397  1   44.305  ? 38   SER A N    1 ? 
ATOM   194   C  CA   . SER A 1 32  ? 17.472  -28.354 -0.139  1   47.358  ? 38   SER A CA   1 ? 
ATOM   195   C  C    . SER A 1 32  ? 18.557  -27.768 -1.039  1   46.266  ? 38   SER A C    1 ? 
ATOM   196   O  O    . SER A 1 32  ? 18.256  -27.129 -2.046  1   40.73   ? 38   SER A O    1 ? 
ATOM   197   C  CB   . SER A 1 32  ? 17.366  -29.838 -0.425  1   47.731  ? 38   SER A CB   1 ? 
ATOM   198   O  OG   . SER A 1 32  ? 16.884  -30.067 -1.75   1   45.03   ? 38   SER A OG   1 ? 
ATOM   199   H  H    . SER A 1 32  ? 16.2    -27.077 -1.108  1   44.924  ? 38   SER A H    1 c 
ATOM   200   H  HA   . SER A 1 32  ? 17.728  -28.221 0.807   1   46.586  ? 38   SER A HA   1 c 
ATOM   201   H  HB2  . SER A 1 32  ? 18.241  -30.252 -0.32   1   47.017  ? 38   SER A HB2  1 c 
ATOM   202   H  HB3  . SER A 1 32  ? 16.755  -30.248 0.218   1   46.982  ? 38   SER A HB3  1 c 
ATOM   203   H  HG   . SER A 1 32  ? 16.857  -30.888 -1.871  0   44.83   ? 38   SER A HG   1 c 
ATOM   204   N  N    . GLU A 1 33  ? 19.797  -28.126 -0.707  1   43.761  ? 39   GLU A N    1 ? 
ATOM   205   C  CA   . GLU A 1 33  ? 20.955  -27.762 -1.494  1   49.815  ? 39   GLU A CA   1 ? 
ATOM   206   C  C    . GLU A 1 33  ? 20.8    -28.278 -2.922  1   47.37   ? 39   GLU A C    1 ? 
ATOM   207   O  O    . GLU A 1 33  ? 21.154  -27.581 -3.868  1   47.205  ? 39   GLU A O    1 ? 
ATOM   208   C  CB   . GLU A 1 33  ? 22.179  -28.374 -0.818  1   51.349  ? 39   GLU A CB   1 ? 
ATOM   209   C  CG   . GLU A 1 33  ? 23.487  -27.932 -1.461  1   56.365  ? 39   GLU A CG   1 ? 
ATOM   210   C  CD   . GLU A 1 33  ? 24.695  -28.507 -0.763  1   52.332  ? 39   GLU A CD   1 ? 
ATOM   211   O  OE1  . GLU A 1 33  ? 25.657  -28.952 -1.431  1   51.589  ? 39   GLU A OE1  1 ? 
ATOM   212   O  OE2  . GLU A 1 33  ? 24.615  -28.523 0.473   1   42.834  ? 39   GLU A OE2  1 ? 
ATOM   213   H  H    . GLU A 1 33  ? 19.923  -28.623 0.05    1   45.792  ? 39   GLU A H    1 c 
ATOM   214   H  HA   . GLU A 1 33  ? 21.034  -26.774 -1.509  1   48.385  ? 39   GLU A HA   1 c 
ATOM   215   H  HB2  . GLU A 1 33  ? 22.178  -28.115 0.127   1   51.977  ? 39   GLU A HB2  1 c 
ATOM   216   H  HB3  . GLU A 1 33  ? 22.11   -29.351 -0.861  1   52.066  ? 39   GLU A HB3  1 c 
ATOM   217   H  HG2  . GLU A 1 33  ? 23.502  -28.215 -2.4    1   54.218  ? 39   GLU A HG2  1 c 
ATOM   218   H  HG3  . GLU A 1 33  ? 23.546  -26.953 -1.437  1   54.247  ? 39   GLU A HG3  1 c 
ATOM   219   N  N    . GLU A 1 34  ? 20.256  -29.495 -3.066  1   44.274  ? 40   GLU A N    1 ? 
ATOM   220   C  CA   . GLU A 1 34  ? 20.196  -30.151 -4.359  1   45.512  ? 40   GLU A CA   1 ? 
ATOM   221   C  C    . GLU A 1 34  ? 19.175  -29.401 -5.203  1   43.536  ? 40   GLU A C    1 ? 
ATOM   222   O  O    . GLU A 1 34  ? 19.405  -29.155 -6.373  1   45.769  ? 40   GLU A O    1 ? 
ATOM   223   C  CB   . GLU A 1 34  ? 19.963  -31.668 -4.384  1   47.93   ? 40   GLU A CB   1 ? 
ATOM   224   C  CG   . GLU A 1 34  ? 19.311  -32.265 -3.146  1   62.73   ? 40   GLU A CG   1 ? 
ATOM   225   C  CD   . GLU A 1 34  ? 20.273  -32.465 -1.993  1   62.041  ? 40   GLU A CD   1 ? 
ATOM   226   O  OE1  . GLU A 1 34  ? 20.093  -31.801 -0.949  1   58.136  ? 40   GLU A OE1  1 ? 
ATOM   227   O  OE2  . GLU A 1 34  ? 21.206  -33.274 -2.163  1   68.375  ? 40   GLU A OE2  1 ? 
ATOM   228   H  H    . GLU A 1 34  ? 19.911  -29.921 -2.336  1   45.586  ? 40   GLU A H    1 c 
ATOM   229   H  HA   . GLU A 1 34  ? 21.079  -30.018 -4.79   1   45.359  ? 40   GLU A HA   1 c 
ATOM   230   H  HB2  . GLU A 1 34  ? 19.4    -31.884 -5.156  1   50.402  ? 40   GLU A HB2  1 c 
ATOM   231   H  HB3  . GLU A 1 34  ? 20.826  -32.111 -4.516  1   50.549  ? 40   GLU A HB3  1 c 
ATOM   232   H  HG2  . GLU A 1 34  ? 18.584  -31.677 -2.85   1   58.564  ? 40   GLU A HG2  1 c 
ATOM   233   H  HG3  . GLU A 1 34  ? 18.915  -33.133 -3.378  1   58.793  ? 40   GLU A HG3  1 c 
ATOM   234   N  N    . GLN A 1 35  ? 18.071  -28.99  -4.592  1   44.254  ? 41   GLN A N    1 ? 
ATOM   235   C  CA   . GLN A 1 35  ? 17.082  -28.2   -5.314  1   46.686  ? 41   GLN A CA   1 ? 
ATOM   236   C  C    . GLN A 1 35  ? 17.624  -26.805 -5.621  1   42.331  ? 41   GLN A C    1 ? 
ATOM   237   O  O    . GLN A 1 35  ? 17.521  -26.371 -6.762  1   42.643  ? 41   GLN A O    1 ? 
ATOM   238   C  CB   . GLN A 1 35  ? 15.79   -28.209 -4.518  1   51.474  ? 41   GLN A CB   1 ? 
ATOM   239   C  CG   . GLN A 1 35  ? 15.202  -29.61  -4.408  1   52.839  ? 41   GLN A CG   1 ? 
ATOM   240   C  CD   . GLN A 1 35  ? 13.973  -29.612 -3.539  1   49.253  ? 41   GLN A CD   1 ? 
ATOM   241   O  OE1  . GLN A 1 35  ? 14.045  -29.651 -2.311  1   48.891  ? 41   GLN A OE1  1 ? 
ATOM   242   N  NE2  . GLN A 1 35  ? 12.83   -29.5   -4.198  1   56.445  ? 41   GLN A NE2  1 ? 
ATOM   243   H  H    . GLN A 1 35  ? 17.923  -29.202 -3.716  1   44.792  ? 41   GLN A H    1 c 
ATOM   244   H  HA   . GLN A 1 35  ? 16.901  -28.654 -6.176  1   46.176  ? 41   GLN A HA   1 c 
ATOM   245   H  HB2  . GLN A 1 35  ? 15.964  -27.861 -3.619  1   50.584  ? 41   GLN A HB2  1 c 
ATOM   246   H  HB3  . GLN A 1 35  ? 15.14   -27.618 -4.952  1   50.628  ? 41   GLN A HB3  1 c 
ATOM   247   H  HG2  . GLN A 1 35  ? 14.968  -29.937 -5.303  1   51.71   ? 41   GLN A HG2  1 c 
ATOM   248   H  HG3  . GLN A 1 35  ? 15.869  -30.219 -4.029  1   51.594  ? 41   GLN A HG3  1 c 
ATOM   249   H  HE21 . GLN A 1 35  ? 12.086  -29.839 -3.851  1   54.118  ? 41   GLN A HE21 1 c 
ATOM   250   H  HE22 . GLN A 1 35  ? 12.806  -29.085 -4.983  1   54.095  ? 41   GLN A HE22 1 c 
ATOM   251   N  N    . LEU A 1 36  ? 18.327  -26.195 -4.646  1   39.81   ? 42   LEU A N    1 ? 
ATOM   252   C  CA   . LEU A 1 36  ? 19.029  -24.941 -4.881  1   39.547  ? 42   LEU A CA   1 ? 
ATOM   253   C  C    . LEU A 1 36  ? 19.973  -25.029 -6.075  1   42.091  ? 42   LEU A C    1 ? 
ATOM   254   O  O    . LEU A 1 36  ? 20.019  -24.129 -6.91   1   38.349  ? 42   LEU A O    1 ? 
ATOM   255   C  CB   . LEU A 1 36  ? 19.805  -24.542 -3.645  1   42.449  ? 42   LEU A CB   1 ? 
ATOM   256   C  CG   . LEU A 1 36  ? 20.655  -23.286 -3.822  1   38.533  ? 42   LEU A CG   1 ? 
ATOM   257   C  CD1  . LEU A 1 36  ? 19.769  -22.054 -3.92   1   37.862  ? 42   LEU A CD1  1 ? 
ATOM   258   C  CD2  . LEU A 1 36  ? 21.588  -23.207 -2.684  1   39.267  ? 42   LEU A CD2  1 ? 
ATOM   259   H  H    . LEU A 1 36  ? 18.362  -26.571 -3.814  1   40.415  ? 42   LEU A H    1 c 
ATOM   260   H  HA   . LEU A 1 36  ? 18.35   -24.245 -5.073  1   40.548  ? 42   LEU A HA   1 c 
ATOM   261   H  HB2  . LEU A 1 36  ? 19.166  -24.388 -2.912  1   40.86   ? 42   LEU A HB2  1 c 
ATOM   262   H  HB3  . LEU A 1 36  ? 20.395  -25.289 -3.393  1   40.871  ? 42   LEU A HB3  1 c 
ATOM   263   H  HG   . LEU A 1 36  ? 21.184  -23.368 -4.656  1   39.247  ? 42   LEU A HG   1 c 
ATOM   264   H  HD11 . LEU A 1 36  ? 19.217  -22.112 -4.718  1   38.083  ? 42   LEU A HD11 1 c 
ATOM   265   H  HD12 . LEU A 1 36  ? 20.323  -21.257 -3.968  1   38.064  ? 42   LEU A HD12 1 c 
ATOM   266   H  HD13 . LEU A 1 36  ? 19.197  -22.002 -3.136  1   38.064  ? 42   LEU A HD13 1 c 
ATOM   267   H  HD21 . LEU A 1 36  ? 22.175  -23.982 -2.69   1   39.059  ? 42   LEU A HD21 1 c 
ATOM   268   H  HD22 . LEU A 1 36  ? 21.085  -23.19  -1.853  1   39.061  ? 42   LEU A HD22 1 c 
ATOM   269   H  HD23 . LEU A 1 36  ? 22.121  -22.398 -2.756  1   39.049  ? 42   LEU A HD23 1 c 
ATOM   270   N  N    . LYS A 1 37  ? 20.73   -26.13  -6.161  1   41.923  ? 43   LYS A N    1 ? 
ATOM   271   C  CA   . LYS A 1 37  ? 21.732  -26.261 -7.205  1   45.637  ? 43   LYS A CA   1 ? 
ATOM   272   C  C    . LYS A 1 37  ? 21.084  -26.201 -8.585  1   39.551  ? 43   LYS A C    1 ? 
ATOM   273   O  O    . LYS A 1 37  ? 21.612  -25.553 -9.491  1   47.576  ? 43   LYS A O    1 ? 
ATOM   274   C  CB   . LYS A 1 37  ? 22.609  -27.489 -6.938  1   45.794  ? 43   LYS A CB   1 ? 
ATOM   275   C  CG   . LYS A 1 37  ? 23.662  -27.682 -7.979  1   50.338  ? 43   LYS A CG   1 ? 
ATOM   276   C  CD   . LYS A 1 37  ? 24.706  -28.72  -7.598  1   54.883  ? 43   LYS A CD   1 ? 
ATOM   277   C  CE   . LYS A 1 37  ? 24.122  -29.978 -7.042  1   56.399  ? 43   LYS A CE   1 ? 
ATOM   278   N  NZ   . LYS A 1 37  ? 25.196  -30.971 -6.914  1   58.743  ? 43   LYS A NZ   1 ? 
ATOM   279   H  H    . LYS A 1 37  ? 20.624  -26.808 -5.558  1   42.75   ? 43   LYS A H    1 c 
ATOM   280   H  HA   . LYS A 1 37  ? 22.331  -25.479 -7.133  1   43.753  ? 43   LYS A HA   1 c 
ATOM   281   H  HB2  . LYS A 1 37  ? 23.04   -27.397 -6.063  1   46.549  ? 43   LYS A HB2  1 c 
ATOM   282   H  HB3  . LYS A 1 37  ? 22.039  -28.288 -6.913  1   46.778  ? 43   LYS A HB3  1 c 
ATOM   283   H  HG2  . LYS A 1 37  ? 23.231  -27.956 -8.817  1   50.159  ? 43   LYS A HG2  1 c 
ATOM   284   H  HG3  . LYS A 1 37  ? 24.108  -26.821 -8.135  1   50.212  ? 43   LYS A HG3  1 c 
ATOM   285   H  HD2  . LYS A 1 37  ? 25.239  -28.94  -8.393  1   54.155  ? 43   LYS A HD2  1 c 
ATOM   286   H  HD3  . LYS A 1 37  ? 25.312  -28.33  -6.931  1   54.157  ? 43   LYS A HD3  1 c 
ATOM   287   H  HE2  . LYS A 1 37  ? 23.73   -29.815 -6.166  1   56.531  ? 43   LYS A HE2  1 c 
ATOM   288   H  HE3  . LYS A 1 37  ? 23.433  -30.321 -7.638  1   56.578  ? 43   LYS A HE3  1 c 
ATOM   289   H  HZ1  . LYS A 1 37  ? 25.85   -30.649 -6.376  1   57.982  ? 43   LYS A HZ1  1 c 
ATOM   290   H  HZ2  . LYS A 1 37  ? 25.545  -31.157 -7.729  1   57.961  ? 43   LYS A HZ2  1 c 
ATOM   291   H  HZ3  . LYS A 1 37  ? 24.864  -31.733 -6.553  1   57.997  ? 43   LYS A HZ3  1 c 
ATOM   292   N  N    . GLU A 1 38  ? 19.899  -26.796 -8.739  1   37.519  ? 44   GLU A N    1 ? 
ATOM   293   C  CA   . GLU A 1 38  ? 19.189  -26.716 -10.008 1   40.553  ? 44   GLU A CA   1 ? 
ATOM   294   C  C    . GLU A 1 38  ? 18.688  -25.296 -10.308 1   38.093  ? 44   GLU A C    1 ? 
ATOM   295   O  O    . GLU A 1 38  ? 18.58   -24.941 -11.461 1   43.973  ? 44   GLU A O    1 ? 
ATOM   296   C  CB   . GLU A 1 38  ? 18.026  -27.713 -10.057 1   45.914  ? 44   GLU A CB   1 ? 
ATOM   297   C  CG   . GLU A 1 38  ? 18.438  -29.163 -9.81   1   41.392  ? 44   GLU A CG   1 ? 
ATOM   298   C  CD   . GLU A 1 38  ? 19.497  -29.678 -10.774 1   44.261  ? 44   GLU A CD   1 ? 
ATOM   299   O  OE1  . GLU A 1 38  ? 20.459  -30.34  -10.321 1   55.84   ? 44   GLU A OE1  1 ? 
ATOM   300   O  OE2  . GLU A 1 38  ? 19.397  -29.365 -11.975 1   48.925  ? 44   GLU A OE2  1 ? 
ATOM   301   H  H    . GLU A 1 38  ? 19.524  -27.256 -8.045  1   38.817  ? 44   GLU A H    1 c 
ATOM   302   H  HA   . GLU A 1 38  ? 19.824  -26.966 -10.724 1   40.555  ? 44   GLU A HA   1 c 
ATOM   303   H  HB2  . GLU A 1 38  ? 17.363  -27.456 -9.382  1   43.601  ? 44   GLU A HB2  1 c 
ATOM   304   H  HB3  . GLU A 1 38  ? 17.595  -27.651 -10.935 1   43.623  ? 44   GLU A HB3  1 c 
ATOM   305   H  HG2  . GLU A 1 38  ? 18.781  -29.248 -8.896  1   43.054  ? 44   GLU A HG2  1 c 
ATOM   306   H  HG3  . GLU A 1 38  ? 17.646  -29.737 -9.883  1   43.036  ? 44   GLU A HG3  1 c 
ATOM   307   N  N    . ALA A 1 39  ? 18.371  -24.496 -9.289  1   36.659  ? 45   ALA A N    1 ? 
ATOM   308   C  CA   . ALA A 1 39  ? 17.877  -23.143 -9.461  1   38.764  ? 45   ALA A CA   1 ? 
ATOM   309   C  C    . ALA A 1 39  ? 18.979  -22.138 -9.818  1   40.98   ? 45   ALA A C    1 ? 
ATOM   310   O  O    . ALA A 1 39  ? 18.663  -21.066 -10.336 1   39.315  ? 45   ALA A O    1 ? 
ATOM   311   C  CB   . ALA A 1 39  ? 17.205  -22.694 -8.193  1   38.277  ? 45   ALA A CB   1 ? 
ATOM   312   H  H    . ALA A 1 39  ? 18.46   -24.818 -8.438  1   37.516  ? 45   ALA A H    1 c 
ATOM   313   H  HA   . ALA A 1 39  ? 17.207  -23.146 -10.199 1   38.667  ? 45   ALA A HA   1 c 
ATOM   314   H  HB1  . ALA A 1 39  ? 16.477  -23.3   -7.976  1   38.425  ? 45   ALA A HB1  1 c 
ATOM   315   H  HB2  . ALA A 1 39  ? 17.848  -22.69  -7.465  1   38.424  ? 45   ALA A HB2  1 c 
ATOM   316   H  HB3  . ALA A 1 39  ? 16.85   -21.796 -8.312  1   38.435  ? 45   ALA A HB3  1 c 
ATOM   317   N  N    . LEU A 1 40  ? 20.249  -22.456 -9.524  1   38.886  ? 46   LEU A N    1 ? 
ATOM   318   C  CA   . LEU A 1 40  ? 21.329  -21.474 -9.57   1   38.247  ? 46   LEU A CA   1 ? 
ATOM   319   C  C    . LEU A 1 40  ? 21.582  -21.069 -11.011 1   37.653  ? 46   LEU A C    1 ? 
ATOM   320   O  O    . LEU A 1 40  ? 21.431  -21.893 -11.906 1   43.758  ? 46   LEU A O    1 ? 
ATOM   321   C  CB   . LEU A 1 40  ? 22.602  -22.027 -8.922  1   40.142  ? 46   LEU A CB   1 ? 
ATOM   322   C  CG   . LEU A 1 40  ? 22.654  -21.951 -7.39   1   44.682  ? 46   LEU A CG   1 ? 
ATOM   323   C  CD1  . LEU A 1 40  ? 23.714  -22.879 -6.809  1   47.434  ? 46   LEU A CD1  1 ? 
ATOM   324   C  CD2  . LEU A 1 40  ? 22.882  -20.528 -6.894  1   43.859  ? 46   LEU A CD2  1 ? 
ATOM   325   H  H    . LEU A 1 40  ? 20.45   -23.314 -9.283  1   39.218  ? 46   LEU A H    1 c 
ATOM   326   H  HA   . LEU A 1 40  ? 21.034  -20.673 -9.068  1   38.649  ? 46   LEU A HA   1 c 
ATOM   327   H  HB2  . LEU A 1 40  ? 22.702  -22.969 -9.192  1   40.735  ? 46   LEU A HB2  1 c 
ATOM   328   H  HB3  . LEU A 1 40  ? 23.372  -21.53  -9.283  1   40.673  ? 46   LEU A HB3  1 c 
ATOM   329   H  HG   . LEU A 1 40  ? 21.775  -22.249 -7.043  1   44.112  ? 46   LEU A HG   1 c 
ATOM   330   H  HD11 . LEU A 1 40  ? 23.583  -23.778 -7.151  1   46.515  ? 46   LEU A HD11 1 c 
ATOM   331   H  HD12 . LEU A 1 40  ? 23.64   -22.887 -5.841  1   46.493  ? 46   LEU A HD12 1 c 
ATOM   332   H  HD13 . LEU A 1 40  ? 24.597  -22.563 -7.064  1   46.567  ? 46   LEU A HD13 1 c 
ATOM   333   H  HD21 . LEU A 1 40  ? 22.138  -19.965 -7.166  1   44.058  ? 46   LEU A HD21 1 c 
ATOM   334   H  HD22 . LEU A 1 40  ? 23.706  -20.18  -7.273  1   44.09   ? 46   LEU A HD22 1 c 
ATOM   335   H  HD23 . LEU A 1 40  ? 22.948  -20.529 -5.924  1   44.09   ? 46   LEU A HD23 1 c 
ATOM   336   N  N    . VAL A 1 41  ? 21.94   -19.799 -11.234 1   35.641  ? 47   VAL A N    1 ? 
ATOM   337   C  CA   . VAL A 1 41  ? 22.159  -19.291 -12.586 1   35.564  ? 47   VAL A CA   1 ? 
ATOM   338   C  C    . VAL A 1 41  ? 23.655  -19.237 -12.811 1   36.404  ? 47   VAL A C    1 ? 
ATOM   339   O  O    . VAL A 1 41  ? 24.324  -18.494 -12.103 1   37.596  ? 47   VAL A O    1 ? 
ATOM   340   C  CB   . VAL A 1 41  ? 21.567  -17.89  -12.841 1   38.789  ? 47   VAL A CB   1 ? 
ATOM   341   C  CG1  . VAL A 1 41  ? 21.881  -17.385 -14.25  1   37.812  ? 47   VAL A CG1  1 ? 
ATOM   342   C  CG2  . VAL A 1 41  ? 20.066  -17.881 -12.63  1   42.649  ? 47   VAL A CG2  1 ? 
ATOM   343   H  H    . VAL A 1 41  ? 22.054  -19.232 -10.526 1   36.128  ? 47   VAL A H    1 c 
ATOM   344   H  HA   . VAL A 1 41  ? 21.766  -19.916 -13.226 1   36.366  ? 47   VAL A HA   1 c 
ATOM   345   H  HB   . VAL A 1 41  ? 21.975  -17.272 -12.19  1   38.668  ? 47   VAL A HB   1 c 
ATOM   346   H  HG11 . VAL A 1 41  ? 21.624  -18.059 -14.902 1   38.105  ? 47   VAL A HG11 1 c 
ATOM   347   H  HG12 . VAL A 1 41  ? 22.833  -17.205 -14.329 1   38.098  ? 47   VAL A HG12 1 c 
ATOM   348   H  HG13 . VAL A 1 41  ? 21.385  -16.566 -14.42  1   38.141  ? 47   VAL A HG13 1 c 
ATOM   349   H  HG21 . VAL A 1 41  ? 19.717  -16.992 -12.81  1   41.436  ? 47   VAL A HG21 1 c 
ATOM   350   H  HG22 . VAL A 1 41  ? 19.865  -18.127 -11.712 1   41.429  ? 47   VAL A HG22 1 c 
ATOM   351   H  HG23 . VAL A 1 41  ? 19.649  -18.519 -13.234 1   41.454  ? 47   VAL A HG23 1 c 
ATOM   352   N  N    . MET A 1 42  ? 24.175  -20.038 -13.742 1   37.275  ? 48   MET A N    1 ? 
ATOM   353   C  CA   . MET A 1 42  ? 25.621  -20.174 -13.864 1   41.171  ? 48   MET A CA   1 ? 
ATOM   354   C  C    . MET A 1 42  ? 26.148  -19.141 -14.853 1   36.981  ? 48   MET A C    1 ? 
ATOM   355   O  O    . MET A 1 42  ? 25.358  -18.425 -15.466 1   36.529  ? 48   MET A O    1 ? 
ATOM   356   C  CB   . MET A 1 42  ? 26.02   -21.585 -14.304 1   41.502  ? 48   MET A CB   1 ? 
ATOM   357   C  CG   . MET A 1 42  ? 25.584  -22.668 -13.316 1   47.819  ? 48   MET A CG   1 ? 
ATOM   358   S  SD   . MET A 1 42  ? 26.323  -22.518 -11.68  1   51.149  ? 48   MET A SD   1 ? 
ATOM   359   C  CE   . MET A 1 42  ? 28.099  -22.698 -11.942 1   51.379  ? 48   MET A CE   1 ? 
ATOM   360   H  H    . MET A 1 42  ? 23.631  -20.504 -14.31  1   37.87   ? 48   MET A H    1 c 
ATOM   361   H  HA   . MET A 1 42  ? 26.026  -19.985 -12.979 1   39.659  ? 48   MET A HA   1 c 
ATOM   362   H  HB2  . MET A 1 42  ? 25.617  -21.768 -15.179 1   42.777  ? 48   MET A HB2  1 c 
ATOM   363   H  HB3  . MET A 1 42  ? 26.994  -21.622 -14.408 1   42.762  ? 48   MET A HB3  1 c 
ATOM   364   H  HG2  . MET A 1 42  ? 24.611  -22.639 -13.22  1   46.774  ? 48   MET A HG2  1 c 
ATOM   365   H  HG3  . MET A 1 42  ? 25.819  -23.544 -13.681 1   46.819  ? 48   MET A HG3  1 c 
ATOM   366   H  HE1  . MET A 1 42  ? 28.558  -22.678 -11.082 1   51.296  ? 48   MET A HE1  1 c 
ATOM   367   H  HE2  . MET A 1 42  ? 28.277  -23.548 -12.387 1   51.267  ? 48   MET A HE2  1 c 
ATOM   368   H  HE3  . MET A 1 42  ? 28.42   -21.967 -12.5   1   51.246  ? 48   MET A HE3  1 c 
ATOM   369   N  N    . ASN A 1 43  ? 27.485  -19.051 -14.932 1   36.608  ? 49   ASN A N    1 ? 
ATOM   370   C  CA   . ASN A 1 43  ? 28.223  -18.209 -15.877 1   41.851  ? 49   ASN A CA   1 ? 
ATOM   371   C  C    . ASN A 1 43  ? 27.826  -16.73  -15.79  1   35.521  ? 49   ASN A C    1 ? 
ATOM   372   O  O    . ASN A 1 43  ? 27.927  -16.007 -16.779 1   33.198  ? 49   ASN A O    1 ? 
ATOM   373   C  CB   . ASN A 1 43  ? 28.052  -18.729 -17.306 1   42.683  ? 49   ASN A CB   1 ? 
ATOM   374   C  CG   . ASN A 1 43  ? 28.46   -20.175 -17.402 1   42.067  ? 49   ASN A CG   1 ? 
ATOM   375   O  OD1  . ASN A 1 43  ? 29.567  -20.49  -16.975 1   41.308  ? 49   ASN A OD1  1 ? 
ATOM   376   N  ND2  . ASN A 1 43  ? 27.59   -21.054 -17.889 1   42.823  ? 49   ASN A ND2  1 ? 
ATOM   377   H  H    . ASN A 1 43  ? 27.976  -19.549 -14.343 1   37.904  ? 49   ASN A H    1 c 
ATOM   378   H  HA   . ASN A 1 43  ? 29.179  -18.276 -15.655 1   39.72   ? 49   ASN A HA   1 c 
ATOM   379   H  HB2  . ASN A 1 43  ? 27.118  -18.635 -17.577 1   42.321  ? 49   ASN A HB2  1 c 
ATOM   380   H  HB3  . ASN A 1 43  ? 28.603  -18.198 -17.915 1   42.29   ? 49   ASN A HB3  1 c 
ATOM   381   H  HD21 . ASN A 1 43  ? 27.809  -21.912 -17.931 1   42.579  ? 49   ASN A HD21 1 c 
ATOM   382   H  HD22 . ASN A 1 43  ? 26.794  -20.785 -18.172 1   42.585  ? 49   ASN A HD22 1 c 
ATOM   383   N  N    . GLN A 1 44  ? 27.352  -16.295 -14.617 1   33.062  ? 50   GLN A N    1 ? 
ATOM   384   C  CA   . GLN A 1 44  ? 27.089  -14.894 -14.313 1   33.199  ? 50   GLN A CA   1 ? 
ATOM   385   C  C    . GLN A 1 44  ? 26.044  -14.292 -15.25  1   36.059  ? 50   GLN A C    1 ? 
ATOM   386   O  O    . GLN A 1 44  ? 26.039  -13.078 -15.481 1   29.892  ? 50   GLN A O    1 ? 
ATOM   387   C  CB   . GLN A 1 44  ? 28.356  -14.039 -14.324 1   34.406  ? 50   GLN A CB   1 ? 
ATOM   388   C  CG   . GLN A 1 44  ? 29.306  -14.349 -13.176 1   35.723  ? 50   GLN A CG   1 ? 
ATOM   389   C  CD   . GLN A 1 44  ? 30.161  -15.558 -13.482 1   35.79   ? 50   GLN A CD   1 ? 
ATOM   390   O  OE1  . GLN A 1 44  ? 30.746  -15.628 -14.566 1   31.785  ? 50   GLN A OE1  1 ? 
ATOM   391   N  NE2  . GLN A 1 44  ? 30.197  -16.527 -12.577 1   31.646  ? 50   GLN A NE2  1 ? 
ATOM   392   H  H    . GLN A 1 44  ? 27.198  -16.908 -13.957 1   33.753  ? 50   GLN A H    1 c 
ATOM   393   H  HA   . GLN A 1 44  ? 26.722  -14.855 -13.396 1   33.834  ? 50   GLN A HA   1 c 
ATOM   394   H  HB2  . GLN A 1 44  ? 28.823  -14.17  -15.174 1   34.407  ? 50   GLN A HB2  1 c 
ATOM   395   H  HB3  . GLN A 1 44  ? 28.1    -13.095 -14.27  1   34.399  ? 50   GLN A HB3  1 c 
ATOM   396   H  HG2  . GLN A 1 44  ? 29.889  -13.576 -13.017 1   35.415  ? 50   GLN A HG2  1 c 
ATOM   397   H  HG3  . GLN A 1 44  ? 28.79   -14.512 -12.36  1   35.329  ? 50   GLN A HG3  1 c 
ATOM   398   H  HE21 . GLN A 1 44  ? 30.658  -17.266 -12.743 1   32.869  ? 50   GLN A HE21 1 c 
ATOM   399   H  HE22 . GLN A 1 44  ? 29.763  -16.439 -11.809 1   32.907  ? 50   GLN A HE22 1 c 
ATOM   400   N  N    . LYS A 1 45  ? 25.108  -15.139 -15.689 1   35.013  ? 51   LYS A N    1 ? 
ATOM   401   C  CA   . LYS A 1 45  ? 24.045  -14.719 -16.58  1   38.366  ? 51   LYS A CA   1 ? 
ATOM   402   C  C    . LYS A 1 45  ? 22.943  -14.021 -15.794 1   39.947  ? 51   LYS A C    1 ? 
ATOM   403   O  O    . LYS A 1 45  ? 22.037  -13.469 -16.392 1   42.464  ? 51   LYS A O    1 ? 
ATOM   404   C  CB   . LYS A 1 45  ? 23.479  -15.923 -17.338 1   42.798  ? 51   LYS A CB   1 ? 
ATOM   405   C  CG   . LYS A 1 45  ? 24.376  -16.354 -18.503 1   54.297  ? 51   LYS A CG   1 ? 
ATOM   406   C  CD   . LYS A 1 45  ? 23.597  -17.151 -19.541 1   76.385  ? 51   LYS A CD   1 ? 
ATOM   407   C  CE   . LYS A 1 45  ? 24.249  -17.237 -20.898 1   85.109  ? 51   LYS A CE   1 ? 
ATOM   408   N  NZ   . LYS A 1 45  ? 23.596  -18.247 -21.749 1   80.162  ? 51   LYS A NZ   1 ? 
ATOM   409   H  H    . LYS A 1 45  ? 25.124  -16.009 -15.408 1   36.053  ? 51   LYS A H    1 c 
ATOM   410   H  HA   . LYS A 1 45  ? 24.421  -14.077 -17.235 1   38.756  ? 51   LYS A HA   1 c 
ATOM   411   H  HB2  . LYS A 1 45  ? 23.378  -16.678 -16.72  1   44.074  ? 51   LYS A HB2  1 c 
ATOM   412   H  HB3  . LYS A 1 45  ? 22.591  -15.696 -17.688 1   44.343  ? 51   LYS A HB3  1 c 
ATOM   413   H  HG2  . LYS A 1 45  ? 24.759  -15.556 -18.926 1   55.37   ? 51   LYS A HG2  1 c 
ATOM   414   H  HG3  . LYS A 1 45  ? 25.111  -16.904 -18.154 1   55.574  ? 51   LYS A HG3  1 c 
ATOM   415   H  HD2  . LYS A 1 45  ? 23.461  -18.06  -19.198 1   72.287  ? 51   LYS A HD2  1 c 
ATOM   416   H  HD3  . LYS A 1 45  ? 22.709  -16.745 -19.647 1   71.92   ? 51   LYS A HD3  1 c 
ATOM   417   H  HE2  . LYS A 1 45  ? 24.201  -16.37  -21.339 1   81.88   ? 51   LYS A HE2  1 c 
ATOM   418   H  HE3  . LYS A 1 45  ? 25.187  -17.47  -20.787 1   81.874  ? 51   LYS A HE3  1 c 
ATOM   419   H  HZ1  . LYS A 1 45  ? 22.721  -18.039 -21.854 1   81.637  ? 51   LYS A HZ1  1 c 
ATOM   420   H  HZ2  . LYS A 1 45  ? 23.664  -19.064 -21.363 1   81.587  ? 51   LYS A HZ2  1 c 
ATOM   421   H  HZ3  . LYS A 1 45  ? 23.996  -18.268 -22.562 1   81.637  ? 51   LYS A HZ3  1 c 
ATOM   422   N  N    . TRP A 1 46  ? 23.025  -14.064 -14.459 1   33.508  ? 52   TRP A N    1 ? 
ATOM   423   C  CA   . TRP A 1 46  ? 22.122  -13.326 -13.593 1   34.166  ? 52   TRP A CA   1 ? 
ATOM   424   C  C    . TRP A 1 46  ? 22.475  -11.832 -13.535 1   37.446  ? 52   TRP A C    1 ? 
ATOM   425   O  O    . TRP A 1 46  ? 21.716  -11.04  -12.981 1   40.24   ? 52   TRP A O    1 ? 
ATOM   426   C  CB   . TRP A 1 46  ? 22.164  -13.959 -12.191 1   30.164  ? 52   TRP A CB   1 ? 
ATOM   427   C  CG   . TRP A 1 46  ? 23.563  -14.016 -11.622 1   30.441  ? 52   TRP A CG   1 ? 
ATOM   428   C  CD1  . TRP A 1 46  ? 24.397  -15.097 -11.695 1   29.952  ? 52   TRP A CD1  1 ? 
ATOM   429   C  CD2  . TRP A 1 46  ? 24.341  -12.951 -11.026 1   28.064  ? 52   TRP A CD2  1 ? 
ATOM   430   N  NE1  . TRP A 1 46  ? 25.615  -14.786 -11.168 1   28.293  ? 52   TRP A NE1  1 ? 
ATOM   431   C  CE2  . TRP A 1 46  ? 25.616  -13.49  -10.734 1   32.27   ? 52   TRP A CE2  1 ? 
ATOM   432   C  CE3  . TRP A 1 46  ? 24.087  -11.626 -10.671 1   32.993  ? 52   TRP A CE3  1 ? 
ATOM   433   C  CZ2  . TRP A 1 46  ? 26.63   -12.746 -10.129 1   31.199  ? 52   TRP A CZ2  1 ? 
ATOM   434   C  CZ3  . TRP A 1 46  ? 25.089  -10.883 -10.082 1   33.392  ? 52   TRP A CZ3  1 ? 
ATOM   435   C  CH2  . TRP A 1 46  ? 26.35   -11.434 -9.824  1   32.785  ? 52   TRP A CH2  1 ? 
ATOM   436   H  H    . TRP A 1 46  ? 23.658  -14.597 -14.074 1   35.017  ? 52   TRP A H    1 c 
ATOM   437   H  HA   . TRP A 1 46  ? 21.198  -13.421 -13.949 1   33.902  ? 52   TRP A HA   1 c 
ATOM   438   H  HB2  . TRP A 1 46  ? 21.598  -13.428 -11.591 1   31.11   ? 52   TRP A HB2  1 c 
ATOM   439   H  HB3  . TRP A 1 46  ? 21.802  -14.869 -12.245 1   31.093  ? 52   TRP A HB3  1 c 
ATOM   440   H  HD1  . TRP A 1 46  ? 24.174  -15.935 -12.065 1   29.734  ? 52   TRP A HD1  1 c 
ATOM   441   H  HE1  . TRP A 1 46  ? 26.285  -15.341 -11.094 1   29.62   ? 52   TRP A HE1  1 c 
ATOM   442   H  HE3  . TRP A 1 46  ? 23.245  -11.241 -10.843 1   31.945  ? 52   TRP A HE3  1 c 
ATOM   443   H  HZ2  . TRP A 1 46  ? 27.478  -13.116 -9.967  1   31.744  ? 52   TRP A HZ2  1 c 
ATOM   444   H  HZ3  . TRP A 1 46  ? 24.923  -9.984  -9.849  1   33.092  ? 52   TRP A HZ3  1 c 
ATOM   445   H  HH2  . TRP A 1 46  ? 27.011  -10.905 -9.414  1   32.513  ? 52   TRP A HH2  1 c 
ATOM   446   N  N    . VAL A 1 47  ? 23.642  -11.431 -14.055 1   37.18   ? 53   VAL A N    1 ? 
ATOM   447   C  CA   . VAL A 1 47  ? 24.111  -10.067 -13.859 1   39.752  ? 53   VAL A CA   1 ? 
ATOM   448   C  C    . VAL A 1 47  ? 23.121  -9.113  -14.526 1   35.266  ? 53   VAL A C    1 ? 
ATOM   449   O  O    . VAL A 1 47  ? 22.85   -9.24   -15.701 1   39.156  ? 53   VAL A O    1 ? 
ATOM   450   C  CB   . VAL A 1 47  ? 25.543  -9.831  -14.362 1   36.141  ? 53   VAL A CB   1 ? 
ATOM   451   C  CG1  . VAL A 1 47  ? 25.826  -8.347  -14.591 1   34.279  ? 53   VAL A CG1  1 ? 
ATOM   452   C  CG2  . VAL A 1 47  ? 26.556  -10.443 -13.394 1   34.98   ? 53   VAL A CG2  1 ? 
ATOM   453   H  H    . VAL A 1 47  ? 24.16   -12.013 -14.531 1   37.739  ? 53   VAL A H    1 c 
ATOM   454   H  HA   . VAL A 1 47  ? 24.103  -9.89   -12.901 1   37.467  ? 53   VAL A HA   1 c 
ATOM   455   H  HB   . VAL A 1 47  ? 25.629  -10.295 -15.228 1   36.218  ? 53   VAL A HB   1 c 
ATOM   456   H  HG11 . VAL A 1 47  ? 25.527  -7.836  -13.819 1   34.796  ? 53   VAL A HG11 1 c 
ATOM   457   H  HG12 . VAL A 1 47  ? 25.355  -8.042  -15.384 1   34.796  ? 53   VAL A HG12 1 c 
ATOM   458   H  HG13 . VAL A 1 47  ? 26.781  -8.215  -14.713 1   34.811  ? 53   VAL A HG13 1 c 
ATOM   459   H  HG21 . VAL A 1 47  ? 27.457  -10.287 -13.725 1   35.32   ? 53   VAL A HG21 1 c 
ATOM   460   H  HG22 . VAL A 1 47  ? 26.399  -11.399 -13.321 1   35.32   ? 53   VAL A HG22 1 c 
ATOM   461   H  HG23 . VAL A 1 47  ? 26.458  -10.032 -12.518 1   35.331  ? 53   VAL A HG23 1 c 
ATOM   462   N  N    . PRO A 1 48  ? 22.503  -8.167  -13.791 1   31.033  ? 54   PRO A N    1 ? 
ATOM   463   C  CA   . PRO A 1 48  ? 21.498  -7.289  -14.383 1   33.609  ? 54   PRO A CA   1 ? 
ATOM   464   C  C    . PRO A 1 48  ? 21.987  -6.023  -15.063 1   34.242  ? 54   PRO A C    1 ? 
ATOM   465   O  O    . PRO A 1 48  ? 21.16   -5.287  -15.62  1   41.521  ? 54   PRO A O    1 ? 
ATOM   466   C  CB   . PRO A 1 48  ? 20.62   -6.955  -13.183 1   28.818  ? 54   PRO A CB   1 ? 
ATOM   467   C  CG   . PRO A 1 48  ? 21.612  -6.879  -12.04  1   28.387  ? 54   PRO A CG   1 ? 
ATOM   468   C  CD   . PRO A 1 48  ? 22.608  -7.998  -12.335 1   29.35   ? 54   PRO A CD   1 ? 
ATOM   469   H  HA   . PRO A 1 48  ? 20.966  -7.817  -15.029 1   32.335  ? 54   PRO A HA   1 c 
ATOM   470   H  HB2  . PRO A 1 48  ? 20.157  -6.093  -13.309 1   29.805  ? 54   PRO A HB2  1 c 
ATOM   471   H  HB3  . PRO A 1 48  ? 19.952  -7.662  -13.026 1   29.743  ? 54   PRO A HB3  1 c 
ATOM   472   H  HG2  . PRO A 1 48  ? 22.06   -6.008  -12.022 1   28.695  ? 54   PRO A HG2  1 c 
ATOM   473   H  HG3  . PRO A 1 48  ? 21.167  -7.026  -11.179 1   28.697  ? 54   PRO A HG3  1 c 
ATOM   474   H  HD2  . PRO A 1 48  ? 23.519  -7.737  -12.074 1   29.581  ? 54   PRO A HD2  1 c 
ATOM   475   H  HD3  . PRO A 1 48  ? 22.36   -8.822  -11.862 1   29.625  ? 54   PRO A HD3  1 c 
ATOM   476   N  N    . TYR A 1 49  ? 23.297  -5.775  -15.012 1   31.682  ? 55   TYR A N    1 ? 
ATOM   477   C  CA   . TYR A 1 49  ? 23.847  -4.579  -15.642 1   30.96   ? 55   TYR A CA   1 ? 
ATOM   478   C  C    . TYR A 1 49  ? 24.287  -4.898  -17.058 1   35.862  ? 55   TYR A C    1 ? 
ATOM   479   O  O    . TYR A 1 49  ? 24.505  -6.061  -17.375 1   35.963  ? 55   TYR A O    1 ? 
ATOM   480   C  CB   . TYR A 1 49  ? 24.989  -3.981  -14.828 1   30.577  ? 55   TYR A CB   1 ? 
ATOM   481   C  CG   . TYR A 1 49  ? 24.684  -4.103  -13.347 1   27.982  ? 55   TYR A CG   1 ? 
ATOM   482   C  CD1  . TYR A 1 49  ? 23.672  -3.367  -12.786 1   25.217  ? 55   TYR A CD1  1 ? 
ATOM   483   C  CD2  . TYR A 1 49  ? 25.333  -5.038  -12.547 1   29.413  ? 55   TYR A CD2  1 ? 
ATOM   484   C  CE1  . TYR A 1 49  ? 23.36   -3.491  -11.447 1   28.39   ? 55   TYR A CE1  1 ? 
ATOM   485   C  CE2  . TYR A 1 49  ? 24.98   -5.225  -11.211 1   29.336  ? 55   TYR A CE2  1 ? 
ATOM   486   C  CZ   . TYR A 1 49  ? 24.011  -4.412  -10.655 1   28.48   ? 55   TYR A CZ   1 ? 
ATOM   487   O  OH   . TYR A 1 49  ? 23.674  -4.483  -9.328  1   30.792  ? 55   TYR A OH   1 ? 
ATOM   488   H  H    . TYR A 1 49  ? 23.861  -6.356  -14.59  1   32.136  ? 55   TYR A H    1 c 
ATOM   489   H  HA   . TYR A 1 49  ? 23.123  -3.902  -15.689 1   31.996  ? 55   TYR A HA   1 c 
ATOM   490   H  HB2  . TYR A 1 49  ? 25.821  -4.462  -15.034 1   30.074  ? 55   TYR A HB2  1 c 
ATOM   491   H  HB3  . TYR A 1 49  ? 25.094  -3.033  -15.065 1   30.076  ? 55   TYR A HB3  1 c 
ATOM   492   H  HD1  . TYR A 1 49  ? 23.221  -2.723  -13.308 1   26.639  ? 55   TYR A HD1  1 c 
ATOM   493   H  HD2  . TYR A 1 49  ? 25.993  -5.594  -12.93  1   29.047  ? 55   TYR A HD2  1 c 
ATOM   494   H  HE1  . TYR A 1 49  ? 22.688  -2.948  -11.072 1   27.676  ? 55   TYR A HE1  1 c 
ATOM   495   H  HE2  . TYR A 1 49  ? 25.46   -5.827  -10.67  1   29.129  ? 55   TYR A HE2  1 c 
ATOM   496   H  HH   . TYR A 1 49  ? 23.032  -5.042  -9.217  0   30.56   ? 55   TYR A HH   1 c 
ATOM   497   N  N    . PRO A 1 50  ? 24.419  -3.873  -17.938 1   38.196  ? 56   PRO A N    1 ? 
ATOM   498   C  CA   . PRO A 1 50  ? 24.953  -4.074  -19.285 1   41.951  ? 56   PRO A CA   1 ? 
ATOM   499   C  C    . PRO A 1 50  ? 26.421  -4.467  -19.241 1   41.647  ? 56   PRO A C    1 ? 
ATOM   500   O  O    . PRO A 1 50  ? 27.148  -3.996  -18.383 1   42.671  ? 56   PRO A O    1 ? 
ATOM   501   C  CB   . PRO A 1 50  ? 24.771  -2.732  -20.006 1   39.266  ? 56   PRO A CB   1 ? 
ATOM   502   C  CG   . PRO A 1 50  ? 23.833  -1.943  -19.112 1   39.382  ? 56   PRO A CG   1 ? 
ATOM   503   C  CD   . PRO A 1 50  ? 24.078  -2.468  -17.697 1   35.237  ? 56   PRO A CD   1 ? 
ATOM   504   H  HA   . PRO A 1 50  ? 24.426  -4.775  -19.744 1   40.678  ? 56   PRO A HA   1 c 
ATOM   505   H  HB2  . PRO A 1 50  ? 25.634  -2.266  -20.107 1   39.88   ? 56   PRO A HB2  1 c 
ATOM   506   H  HB3  . PRO A 1 50  ? 24.376  -2.864  -20.9   1   39.876  ? 56   PRO A HB3  1 c 
ATOM   507   H  HG2  . PRO A 1 50  ? 24.03   -0.984  -19.164 1   38.385  ? 56   PRO A HG2  1 c 
ATOM   508   H  HG3  . PRO A 1 50  ? 22.9    -2.086  -19.377 1   38.385  ? 56   PRO A HG3  1 c 
ATOM   509   H  HD2  . PRO A 1 50  ? 24.82   -1.99   -17.264 1   36.785  ? 56   PRO A HD2  1 c 
ATOM   510   H  HD3  . PRO A 1 50  ? 23.269  -2.382  -17.146 1   36.726  ? 56   PRO A HD3  1 c 
ATOM   511   N  N    . ALA A 1 51  ? 26.851  -5.253  -20.233 1   41.494  ? 57   ALA A N    1 ? 
ATOM   512   C  CA   . ALA A 1 51  ? 28.255  -5.606  -20.41  1   39.817  ? 57   ALA A CA   1 ? 
ATOM   513   C  C    . ALA A 1 51  ? 29.11   -4.342  -20.495 1   37.251  ? 57   ALA A C    1 ? 
ATOM   514   O  O    . ALA A 1 51  ? 28.646  -3.295  -20.949 1   35.458  ? 57   ALA A O    1 ? 
ATOM   515   C  CB   . ALA A 1 51  ? 28.401  -6.453  -21.667 1   40.89   ? 57   ALA A CB   1 ? 
ATOM   516   H  H    . ALA A 1 51  ? 26.242  -5.584  -20.829 1   41.145  ? 57   ALA A H    1 c 
ATOM   517   H  HA   . ALA A 1 51  ? 28.547  -6.134  -19.618 1   39.848  ? 57   ALA A HA   1 c 
ATOM   518   H  HB1  . ALA A 1 51  ? 27.872  -7.264  -21.578 1   40.571  ? 57   ALA A HB1  1 c 
ATOM   519   H  HB2  . ALA A 1 51  ? 28.091  -5.95   -22.438 1   40.571  ? 57   ALA A HB2  1 c 
ATOM   520   H  HB3  . ALA A 1 51  ? 29.335  -6.691  -21.794 1   40.571  ? 57   ALA A HB3  1 c 
ATOM   521   N  N    . TYR A 1 52  ? 30.345  -4.446  -19.999 1   33.673  ? 58   TYR A N    1 ? 
ATOM   522   C  CA   . TYR A 1 52  ? 31.328  -3.375  -20.048 1   35.063  ? 58   TYR A CA   1 ? 
ATOM   523   C  C    . TYR A 1 52  ? 31.453  -2.851  -21.472 1   35.664  ? 58   TYR A C    1 ? 
ATOM   524   O  O    . TYR A 1 52  ? 31.452  -1.64   -21.687 1   39.522  ? 58   TYR A O    1 ? 
ATOM   525   C  CB   . TYR A 1 52  ? 32.695  -3.858  -19.538 1   33.042  ? 58   TYR A CB   1 ? 
ATOM   526   C  CG   . TYR A 1 52  ? 33.859  -2.889  -19.707 1   34.154  ? 58   TYR A CG   1 ? 
ATOM   527   C  CD1  . TYR A 1 52  ? 33.713  -1.535  -19.472 1   35.473  ? 58   TYR A CD1  1 ? 
ATOM   528   C  CD2  . TYR A 1 52  ? 35.109  -3.326  -20.146 1   35.99   ? 58   TYR A CD2  1 ? 
ATOM   529   C  CE1  . TYR A 1 52  ? 34.768  -0.647  -19.645 1   41.489  ? 58   TYR A CE1  1 ? 
ATOM   530   C  CE2  . TYR A 1 52  ? 36.183  -2.453  -20.274 1   33.882  ? 58   TYR A CE2  1 ? 
ATOM   531   C  CZ   . TYR A 1 52  ? 36.026  -1.109  -20.009 1   35.55   ? 58   TYR A CZ   1 ? 
ATOM   532   O  OH   . TYR A 1 52  ? 37.069  -0.197  -20.151 1   37.134  ? 58   TYR A OH   1 ? 
ATOM   533   H  H    . TYR A 1 52  ? 30.59   -5.235  -19.607 1   34.87   ? 58   TYR A H    1 c 
ATOM   534   H  HA   . TYR A 1 52  ? 31.015  -2.635  -19.464 1   34.535  ? 58   TYR A HA   1 c 
ATOM   535   H  HB2  . TYR A 1 52  ? 32.606  -4.074  -18.584 1   33.758  ? 58   TYR A HB2  1 c 
ATOM   536   H  HB3  . TYR A 1 52  ? 32.917  -4.695  -20.005 1   33.816  ? 58   TYR A HB3  1 c 
ATOM   537   H  HD1  . TYR A 1 52  ? 32.875  -1.202  -19.194 1   36.419  ? 58   TYR A HD1  1 c 
ATOM   538   H  HD2  . TYR A 1 52  ? 35.247  -4.247  -20.298 1   35.074  ? 58   TYR A HD2  1 c 
ATOM   539   H  HE1  . TYR A 1 52  ? 34.648  0.266   -19.446 1   38.502  ? 58   TYR A HE1  1 c 
ATOM   540   H  HE2  . TYR A 1 52  ? 37.022  -2.779  -20.549 1   34.834  ? 58   TYR A HE2  1 c 
ATOM   541   H  HH   . TYR A 1 52  ? 37.474  -0.089  -19.394 0   36.22   ? 58   TYR A HH   1 c 
ATOM   542   N  N    . ASN A 1 53  ? 31.505  -3.765  -22.437 1   38.7    ? 59   ASN A N    1 ? 
ATOM   543   C  CA   . ASN A 1 53  ? 31.613  -3.38   -23.839 1   46.141  ? 59   ASN A CA   1 ? 
ATOM   544   C  C    . ASN A 1 53  ? 30.276  -3.013  -24.49  1   49.315  ? 59   ASN A C    1 ? 
ATOM   545   O  O    . ASN A 1 53  ? 30.244  -2.822  -25.695 1   53.047  ? 59   ASN A O    1 ? 
ATOM   546   C  CB   . ASN A 1 53  ? 32.219  -4.5    -24.678 1   51.933  ? 59   ASN A CB   1 ? 
ATOM   547   C  CG   . ASN A 1 53  ? 31.263  -5.659  -24.814 1   56.538  ? 59   ASN A CG   1 ? 
ATOM   548   O  OD1  . ASN A 1 53  ? 30.08   -5.535  -24.48  1   67.373  ? 59   ASN A OD1  1 ? 
ATOM   549   N  ND2  . ASN A 1 53  ? 31.745  -6.79   -25.298 1   64.666  ? 59   ASN A ND2  1 ? 
ATOM   550   H  H    . ASN A 1 53  ? 31.481  -4.653  -22.222 1   39.549  ? 59   ASN A H    1 c 
ATOM   551   H  HA   . ASN A 1 53  ? 32.216  -2.604  -23.902 1   46.025  ? 59   ASN A HA   1 c 
ATOM   552   H  HB2  . ASN A 1 53  ? 32.442  -4.158  -25.567 1   51.565  ? 59   ASN A HB2  1 c 
ATOM   553   H  HB3  . ASN A 1 53  ? 33.044  -4.81   -24.255 1   51.558  ? 59   ASN A HB3  1 c 
ATOM   554   H  HD21 . ASN A 1 53  ? 31.211  -7.492  -25.397 1   62.067  ? 59   ASN A HD21 1 c 
ATOM   555   H  HD22 . ASN A 1 53  ? 32.601  -6.848  -25.523 1   61.976  ? 59   ASN A HD22 1 c 
ATOM   556   N  N    . ASP A 1 54  ? 29.156  -2.976  -23.758 1   48.497  ? 60   ASP A N    1 ? 
ATOM   557   C  CA   . ASP A 1 54  ? 27.904  -2.533  -24.346 1   45.07   ? 60   ASP A CA   1 ? 
ATOM   558   C  C    . ASP A 1 54  ? 27.725  -1.054  -24.04  1   43.624  ? 60   ASP A C    1 ? 
ATOM   559   O  O    . ASP A 1 54  ? 26.922  -0.675  -23.189 1   37.153  ? 60   ASP A O    1 ? 
ATOM   560   C  CB   . ASP A 1 54  ? 26.723  -3.398  -23.938 1   47.075  ? 60   ASP A CB   1 ? 
ATOM   561   C  CG   . ASP A 1 54  ? 25.34   -2.812  -24.223 1   58.778  ? 60   ASP A CG   1 ? 
ATOM   562   O  OD1  . ASP A 1 54  ? 25.248  -1.815  -24.97  1   54.829  ? 60   ASP A OD1  1 ? 
ATOM   563   O  OD2  . ASP A 1 54  ? 24.348  -3.32   -23.645 1   63.633  ? 60   ASP A OD2  1 ? 
ATOM   564   H  H    . ASP A 1 54  ? 29.168  -3.236  -22.883 1   47.661  ? 60   ASP A H    1 c 
ATOM   565   H  HA   . ASP A 1 54  ? 27.974  -2.631  -25.322 1   45.851  ? 60   ASP A HA   1 c 
ATOM   566   H  HB2  . ASP A 1 54  ? 26.79   -4.257  -24.403 1   49.044  ? 60   ASP A HB2  1 c 
ATOM   567   H  HB3  . ASP A 1 54  ? 26.784  -3.573  -22.975 1   49.045  ? 60   ASP A HB3  1 c 
ATOM   568   N  N    . ARG A 1 55  ? 28.429  -0.212  -24.799 1   41.894  ? 61   ARG A N    1 ? 
ATOM   569   C  CA   . ARG A 1 55  ? 28.41   1.212   -24.531 1   40.213  ? 61   ARG A CA   1 ? 
ATOM   570   C  C    . ARG A 1 55  ? 26.99   1.768   -24.619 1   45.823  ? 61   ARG A C    1 ? 
ATOM   571   O  O    . ARG A 1 55  ? 26.596  2.579   -23.779 1   54.575  ? 61   ARG A O    1 ? 
ATOM   572   C  CB   . ARG A 1 55  ? 29.347  1.96    -25.483 1   42.808  ? 61   ARG A CB   1 ? 
ATOM   573   C  CG   . ARG A 1 55  ? 30.837  1.67    -25.326 1   45.374  ? 61   ARG A CG   1 ? 
ATOM   574   C  CD   . ARG A 1 55  ? 31.411  2.36    -24.065 1   40.599  ? 61   ARG A CD   1 ? 
ATOM   575   N  NE   . ARG A 1 55  ? 31.271  1.44    -22.939 1   36.653  ? 61   ARG A NE   1 ? 
ATOM   576   C  CZ   . ARG A 1 55  ? 30.865  1.697   -21.698 1   37.22   ? 61   ARG A CZ   1 ? 
ATOM   577   N  NH1  . ARG A 1 55  ? 30.515  2.901   -21.285 1   33.151  ? 61   ARG A NH1  1 ? 
ATOM   578   N  NH2  . ARG A 1 55  ? 30.868  0.699   -20.841 1   39.099  ? 61   ARG A NH2  1 ? 
ATOM   579   H  H    . ARG A 1 55  ? 28.93   -0.53   -25.495 1   41.979  ? 61   ARG A H    1 c 
ATOM   580   H  HA   . ARG A 1 55  ? 28.735  1.351   -23.607 1   41.949  ? 61   ARG A HA   1 c 
ATOM   581   H  HB2  . ARG A 1 55  ? 29.086  1.74    -26.403 1   42.767  ? 61   ARG A HB2  1 c 
ATOM   582   H  HB3  . ARG A 1 55  ? 29.204  2.923   -25.362 1   42.767  ? 61   ARG A HB3  1 c 
ATOM   583   H  HG2  . ARG A 1 55  ? 30.977  0.701   -25.259 1   43.564  ? 61   ARG A HG2  1 c 
ATOM   584   H  HG3  . ARG A 1 55  ? 31.318  1.996   -26.118 1   43.654  ? 61   ARG A HG3  1 c 
ATOM   585   H  HD2  . ARG A 1 55  ? 32.357  2.574   -24.198 1   40.585  ? 61   ARG A HD2  1 c 
ATOM   586   H  HD3  . ARG A 1 55  ? 30.925  3.188   -23.878 1   40.52   ? 61   ARG A HD3  1 c 
ATOM   587   H  HE   . ARG A 1 55  ? 31.486  0.61    -23.095 1   37.789  ? 61   ARG A HE   1 c 
ATOM   588   H  HH11 . ARG A 1 55  ? 30.905  3.62    -21.629 1   34.454  ? 61   ARG A HH11 1 c 
ATOM   589   H  HH12 . ARG A 1 55  ? 29.892  2.985   -20.658 1   34.438  ? 61   ARG A HH12 1 c 
ATOM   590   H  HH21 . ARG A 1 55  ? 31.358  -0.02   -20.997 1   38.456  ? 61   ARG A HH21 1 c 
ATOM   591   H  HH22 . ARG A 1 55  ? 30.383  0.754   -20.103 1   38.425  ? 61   ARG A HH22 1 c 
ATOM   592   N  N    . ALA A 1 56  ? 26.237  1.351   -25.641 1   44.594  ? 62   ALA A N    1 ? 
ATOM   593   C  CA   . ALA A 1 56  ? 24.879  1.863   -25.864 1   46.088  ? 62   ALA A CA   1 ? 
ATOM   594   C  C    . ALA A 1 56  ? 23.999  1.574   -24.646 1   39.784  ? 62   ALA A C    1 ? 
ATOM   595   O  O    . ALA A 1 56  ? 23.273  2.435   -24.145 1   41.639  ? 62   ALA A O    1 ? 
ATOM   596   C  CB   . ALA A 1 56  ? 24.305  1.237   -27.136 1   39.43   ? 62   ALA A CB   1 ? 
ATOM   597   H  H    . ALA A 1 56  ? 26.574  0.734   -26.225 1   45.115  ? 62   ALA A H    1 c 
ATOM   598   H  HA   . ALA A 1 56  ? 24.934  2.851   -25.982 1   43.333  ? 62   ALA A HA   1 c 
ATOM   599   H  HB1  . ALA A 1 56  ? 24.867  1.466   -27.895 1   41.278  ? 62   ALA A HB1  1 c 
ATOM   600   H  HB2  . ALA A 1 56  ? 24.274  0.27    -27.04  1   41.278  ? 62   ALA A HB2  1 c 
ATOM   601   H  HB3  . ALA A 1 56  ? 23.406  1.574   -27.289 1   41.278  ? 62   ALA A HB3  1 c 
ATOM   602   N  N    . GLY A 1 57  ? 24.114  0.35    -24.127 1   43.888  ? 63   GLY A N    1 ? 
ATOM   603   C  CA   . GLY A 1 57  ? 23.401  -0.026  -22.908 1   48.022  ? 63   GLY A CA   1 ? 
ATOM   604   C  C    . GLY A 1 57  ? 23.737  0.873   -21.715 1   42.07   ? 63   GLY A C    1 ? 
ATOM   605   O  O    . GLY A 1 57  ? 22.84   1.327   -21.002 1   46.788  ? 63   GLY A O    1 ? 
ATOM   606   H  H    . GLY A 1 57  ? 24.642  -0.269  -24.541 1   43.844  ? 63   GLY A H    1 c 
ATOM   607   H  HA2  . GLY A 1 57  ? 22.431  0.015   -23.082 1   45.656  ? 63   GLY A HA2  1 c 
ATOM   608   H  HA3  . GLY A 1 57  ? 23.625  -0.959  -22.684 1   45.721  ? 63   GLY A HA3  1 c 
ATOM   609   N  N    . TRP A 1 58  ? 25.04   1.122   -21.487 1   37.461  ? 64   TRP A N    1 ? 
ATOM   610   C  CA   . TRP A 1 58  ? 25.448  1.948   -20.361 1   36.244  ? 64   TRP A CA   1 ? 
ATOM   611   C  C    . TRP A 1 58  ? 24.948  3.38    -20.512 1   43.605  ? 64   TRP A C    1 ? 
ATOM   612   O  O    . TRP A 1 58  ? 24.579  3.987   -19.505 1   41.507  ? 64   TRP A O    1 ? 
ATOM   613   C  CB   . TRP A 1 58  ? 26.964  1.879   -20.121 1   34.754  ? 64   TRP A CB   1 ? 
ATOM   614   C  CG   . TRP A 1 58  ? 27.342  0.637   -19.358 1   34.526  ? 64   TRP A CG   1 ? 
ATOM   615   C  CD1  . TRP A 1 58  ? 27.854  -0.528  -19.842 1   38.834  ? 64   TRP A CD1  1 ? 
ATOM   616   C  CD2  . TRP A 1 58  ? 27.126  0.413   -17.946 1   32.462  ? 64   TRP A CD2  1 ? 
ATOM   617   N  NE1  . TRP A 1 58  ? 28.007  -1.448  -18.826 1   41.797  ? 64   TRP A NE1  1 ? 
ATOM   618   C  CE2  . TRP A 1 58  ? 27.561  -0.895  -17.654 1   34.783  ? 64   TRP A CE2  1 ? 
ATOM   619   C  CE3  . TRP A 1 58  ? 26.613  1.19    -16.906 1   37.512  ? 64   TRP A CE3  1 ? 
ATOM   620   C  CZ2  . TRP A 1 58  ? 27.508  -1.426  -16.368 1   36.77   ? 64   TRP A CZ2  1 ? 
ATOM   621   C  CZ3  . TRP A 1 58  ? 26.552  0.663   -15.629 1   38.161  ? 64   TRP A CZ3  1 ? 
ATOM   622   C  CH2  . TRP A 1 58  ? 27.01   -0.623  -15.368 1   35.065  ? 64   TRP A CH2  1 ? 
ATOM   623   H  H    . TRP A 1 58  ? 25.677  0.769   -22.038 1   38.269  ? 64   TRP A H    1 c 
ATOM   624   H  HA   . TRP A 1 58  ? 25.01   1.57    -19.551 1   37.508  ? 64   TRP A HA   1 c 
ATOM   625   H  HB2  . TRP A 1 58  ? 27.424  1.879   -20.988 1   35.061  ? 64   TRP A HB2  1 c 
ATOM   626   H  HB3  . TRP A 1 58  ? 27.241  2.669   -19.609 1   35.079  ? 64   TRP A HB3  1 c 
ATOM   627   H  HD1  . TRP A 1 58  ? 28.095  -0.683  -20.741 1   38.348  ? 64   TRP A HD1  1 c 
ATOM   628   H  HE1  . TRP A 1 58  ? 28.336  -2.25   -18.913 1   39.255  ? 64   TRP A HE1  1 c 
ATOM   629   H  HE3  . TRP A 1 58  ? 26.319  2.069   -17.073 1   36.423  ? 64   TRP A HE3  1 c 
ATOM   630   H  HZ2  . TRP A 1 58  ? 27.804  -2.302  -16.191 1   35.94   ? 64   TRP A HZ2  1 c 
ATOM   631   H  HZ3  . TRP A 1 58  ? 26.216  1.19    -14.923 1   37.179  ? 64   TRP A HZ3  1 c 
ATOM   632   H  HH2  . TRP A 1 58  ? 26.949  -0.965  -14.493 1   36.163  ? 64   TRP A HH2  1 c 
ATOM   633   N  N    . ASN A 1 59  ? 24.956  3.92    -21.748 1   47.842  ? 65   ASN A N    1 ? 
ATOM   634   C  CA   . ASN A 1 59  ? 24.458  5.271   -21.993 1   50.469  ? 65   ASN A CA   1 ? 
ATOM   635   C  C    . ASN A 1 59  ? 22.968  5.369   -21.675 1   49.097  ? 65   ASN A C    1 ? 
ATOM   636   O  O    . ASN A 1 59  ? 22.525  6.302   -20.996 1   46.732  ? 65   ASN A O    1 ? 
ATOM   637   C  CB   . ASN A 1 59  ? 24.645  5.713   -23.438 1   53.358  ? 65   ASN A CB   1 ? 
ATOM   638   C  CG   . ASN A 1 59  ? 26.093  5.945   -23.781 1   55.491  ? 65   ASN A CG   1 ? 
ATOM   639   O  OD1  . ASN A 1 59  ? 26.903  6.265   -22.899 1   51.936  ? 65   ASN A OD1  1 ? 
ATOM   640   N  ND2  . ASN A 1 59  ? 26.419  5.837   -25.063 1   49.909  ? 65   ASN A ND2  1 ? 
ATOM   641   H  H    . ASN A 1 59  ? 25.285  3.436   -22.45  1   47.236  ? 65   ASN A H    1 c 
ATOM   642   H  HA   . ASN A 1 59  ? 24.949  5.898   -21.415 1   50.248  ? 65   ASN A HA   1 c 
ATOM   643   H  HB2  . ASN A 1 59  ? 24.282  5.027   -24.033 1   53.161  ? 65   ASN A HB2  1 c 
ATOM   644   H  HB3  . ASN A 1 59  ? 24.145  6.54    -23.59  1   53.142  ? 65   ASN A HB3  1 c 
ATOM   645   H  HD21 . ASN A 1 59  ? 27.264  5.703   -25.293 1   51.567  ? 65   ASN A HD21 1 c 
ATOM   646   H  HD22 . ASN A 1 59  ? 25.791  5.902   -25.686 1   51.577  ? 65   ASN A HD22 1 c 
ATOM   647   N  N    . GLU A 1 60  ? 22.196  4.409   -22.192 1   47.603  ? 66   GLU A N    1 ? 
ATOM   648   C  CA   . GLU A 1 60  ? 20.769  4.392   -21.914 1   55.818  ? 66   GLU A CA   1 ? 
ATOM   649   C  C    . GLU A 1 60  ? 20.502  4.329   -20.404 1   48.097  ? 66   GLU A C    1 ? 
ATOM   650   O  O    . GLU A 1 60  ? 19.664  5.059   -19.877 1   46.142  ? 66   GLU A O    1 ? 
ATOM   651   C  CB   . GLU A 1 60  ? 20.07   3.254   -22.668 1   63.471  ? 66   GLU A CB   1 ? 
ATOM   652   C  CG   . GLU A 1 60  ? 18.569  3.514   -22.811 1   73.409  ? 66   GLU A CG   1 ? 
ATOM   653   C  CD   . GLU A 1 60  ? 17.759  2.29    -23.169 1   77.3    ? 66   GLU A CD   1 ? 
ATOM   654   O  OE1  . GLU A 1 60  ? 16.686  2.085   -22.561 1   71.445  ? 66   GLU A OE1  1 ? 
ATOM   655   O  OE2  . GLU A 1 60  ? 18.239  1.527   -24.035 1   88.403  ? 66   GLU A OE2  1 ? 
ATOM   656   H  H    . GLU A 1 60  ? 22.558  3.761   -22.726 1   49.871  ? 66   GLU A H    1 c 
ATOM   657   H  HA   . GLU A 1 60  ? 20.389  5.243   -22.252 1   53.95   ? 66   GLU A HA   1 c 
ATOM   658   H  HB2  . GLU A 1 60  ? 20.471  3.167   -23.558 1   63.587  ? 66   GLU A HB2  1 c 
ATOM   659   H  HB3  . GLU A 1 60  ? 20.218  2.412   -22.187 1   63.587  ? 66   GLU A HB3  1 c 
ATOM   660   H  HG2  . GLU A 1 60  ? 18.225  3.876   -21.965 1   71.745  ? 66   GLU A HG2  1 c 
ATOM   661   H  HG3  . GLU A 1 60  ? 18.426  4.196   -23.503 1   71.861  ? 66   GLU A HG3  1 c 
ATOM   662   N  N    . LEU A 1 61  ? 21.235  3.47    -19.696 1   41.575  ? 67   LEU A N    1 ? 
ATOM   663   C  CA   . LEU A 1 61  ? 21.01   3.272   -18.269 1   42.532  ? 67   LEU A CA   1 ? 
ATOM   664   C  C    . LEU A 1 61  ? 21.457  4.449   -17.424 1   44.888  ? 67   LEU A C    1 ? 
ATOM   665   O  O    . LEU A 1 61  ? 20.808  4.797   -16.445 1   49.054  ? 67   LEU A O    1 ? 
ATOM   666   C  CB   . LEU A 1 61  ? 21.765  2.025   -17.84  1   46.646  ? 67   LEU A CB   1 ? 
ATOM   667   C  CG   . LEU A 1 61  ? 21.384  1.5     -16.465 1   44.059  ? 67   LEU A CG   1 ? 
ATOM   668   C  CD1  . LEU A 1 61  ? 19.884  1.397   -16.371 1   48.267  ? 67   LEU A CD1  1 ? 
ATOM   669   C  CD2  . LEU A 1 61  ? 22.083  0.15    -16.279 1   45.539  ? 67   LEU A CD2  1 ? 
ATOM   670   H  H    . LEU A 1 61  ? 21.894  2.991   -20.11  1   43.405  ? 67   LEU A H    1 c 
ATOM   671   H  HA   . LEU A 1 61  ? 20.041  3.135   -18.13  1   43.597  ? 67   LEU A HA   1 c 
ATOM   672   H  HB2  . LEU A 1 61  ? 21.595  1.317   -18.503 1   45.05   ? 67   LEU A HB2  1 c 
ATOM   673   H  HB3  . LEU A 1 61  ? 22.729  2.228   -17.843 1   45.074  ? 67   LEU A HB3  1 c 
ATOM   674   H  HG   . LEU A 1 61  ? 21.712  2.134   -15.777 1   45.386  ? 67   LEU A HG   1 c 
ATOM   675   H  HD11 . LEU A 1 61  ? 19.506  2.275   -16.192 1   46.884  ? 67   LEU A HD11 1 c 
ATOM   676   H  HD12 . LEU A 1 61  ? 19.646  0.793   -15.647 1   46.833  ? 67   LEU A HD12 1 c 
ATOM   677   H  HD13 . LEU A 1 61  ? 19.526  1.053   -17.207 1   46.889  ? 67   LEU A HD13 1 c 
ATOM   678   H  HD21 . LEU A 1 61  ? 23.044  0.268   -16.354 1   45.1    ? 67   LEU A HD21 1 c 
ATOM   679   H  HD22 . LEU A 1 61  ? 21.779  -0.471  -16.963 1   45.1    ? 67   LEU A HD22 1 c 
ATOM   680   H  HD23 . LEU A 1 61  ? 21.869  -0.208  -15.401 1   45.1    ? 67   LEU A HD23 1 c 
ATOM   681   N  N    . LEU A 1 62  ? 22.608  5.037   -17.739 1   44.794  ? 68   LEU A N    1 ? 
ATOM   682   C  CA   . LEU A 1 62  ? 23.083  6.145   -16.917 1   49.671  ? 68   LEU A CA   1 ? 
ATOM   683   C  C    . LEU A 1 62  ? 22.31   7.45    -17.145 1   44.961  ? 68   LEU A C    1 ? 
ATOM   684   O  O    . LEU A 1 62  ? 22.178  8.252   -16.237 1   56.923  ? 68   LEU A O    1 ? 
ATOM   685   C  CB   . LEU A 1 62  ? 24.581  6.321   -17.166 1   50.378  ? 68   LEU A CB   1 ? 
ATOM   686   C  CG   . LEU A 1 62  ? 25.475  5.28    -16.486 1   48.462  ? 68   LEU A CG   1 ? 
ATOM   687   C  CD1  . LEU A 1 62  ? 26.854  5.143   -17.108 1   46.739  ? 68   LEU A CD1  1 ? 
ATOM   688   C  CD2  . LEU A 1 62  ? 25.544  5.671   -15.041 1   46.729  ? 68   LEU A CD2  1 ? 
ATOM   689   H  H    . LEU A 1 62  ? 23.099  4.758   -18.458 1   45.869  ? 68   LEU A H    1 c 
ATOM   690   H  HA   . LEU A 1 62  ? 22.953  5.888   -15.97  1   47.898  ? 68   LEU A HA   1 c 
ATOM   691   H  HB2  . LEU A 1 62  ? 24.741  6.285   -18.137 1   49.688  ? 68   LEU A HB2  1 c 
ATOM   692   H  HB3  . LEU A 1 62  ? 24.845  7.217   -16.852 1   49.696  ? 68   LEU A HB3  1 c 
ATOM   693   H  HG   . LEU A 1 62  ? 25.023  4.399   -16.545 1   48.149  ? 68   LEU A HG   1 c 
ATOM   694   H  HD11 . LEU A 1 62  ? 26.766  4.865   -18.036 1   47.226  ? 68   LEU A HD11 1 c 
ATOM   695   H  HD12 . LEU A 1 62  ? 27.367  4.479   -16.619 1   47.226  ? 68   LEU A HD12 1 c 
ATOM   696   H  HD13 . LEU A 1 62  ? 27.313  5.999   -17.07  1   47.175  ? 68   LEU A HD13 1 c 
ATOM   697   H  HD21 . LEU A 1 62  ? 24.667  5.578   -14.634 1   47.242  ? 68   LEU A HD21 1 c 
ATOM   698   H  HD22 . LEU A 1 62  ? 25.839  6.594   -14.965 1   47.212  ? 68   LEU A HD22 1 c 
ATOM   699   H  HD23 . LEU A 1 62  ? 26.175  5.093   -14.579 1   47.199  ? 68   LEU A HD23 1 c 
ATOM   700   N  N    . GLY A 1 63  ? 21.899  7.75    -18.368 1   47.986  ? 69   GLY A N    1 ? 
ATOM   701   C  CA   . GLY A 1 63  ? 21.339  9.069   -18.641 1   53.369  ? 69   GLY A CA   1 ? 
ATOM   702   C  C    . GLY A 1 63  ? 22.29   10.21   -18.266 1   54.677  ? 69   GLY A C    1 ? 
ATOM   703   O  O    . GLY A 1 63  ? 23.471  10.198  -18.601 1   53.224  ? 69   GLY A O    1 ? 
ATOM   704   H  H    . GLY A 1 63  ? 21.965  7.14    -19.044 1   48.366  ? 69   GLY A H    1 c 
ATOM   705   H  HA2  . GLY A 1 63  ? 21.124  9.129   -19.602 1   52.321  ? 69   GLY A HA2  1 c 
ATOM   706   H  HA3  . GLY A 1 63  ? 20.496  9.165   -18.14  1   52.354  ? 69   GLY A HA3  1 c 
ATOM   707   N  N    . THR A 1 64  ? 21.759  11.178  -17.515 1   52.867  ? 70   THR A N    1 ? 
ATOM   708   C  CA   . THR A 1 64  ? 22.493  12.366  -17.11  1   57.851  ? 70   THR A CA   1 ? 
ATOM   709   C  C    . THR A 1 64  ? 23.496  12.052  -15.994 1   56.357  ? 70   THR A C    1 ? 
ATOM   710   O  O    . THR A 1 64  ? 24.368  12.873  -15.72  1   67.014  ? 70   THR A O    1 ? 
ATOM   711   C  CB   . THR A 1 64  ? 21.533  13.493  -16.696 1   65.395  ? 70   THR A CB   1 ? 
ATOM   712   O  OG1  . THR A 1 64  ? 20.852  13.181  -15.479 1   64.621  ? 70   THR A OG1  1 ? 
ATOM   713   C  CG2  . THR A 1 64  ? 20.484  13.786  -17.754 1   65.341  ? 70   THR A CG2  1 ? 
ATOM   714   H  H    . THR A 1 64  ? 20.896  11.084  -17.227 1   54.565  ? 70   THR A H    1 c 
ATOM   715   H  HA   . THR A 1 64  ? 22.998  12.68   -17.89  1   57.768  ? 70   THR A HA   1 c 
ATOM   716   H  HB   . THR A 1 64  ? 22.06   14.316  -16.559 1   63.797  ? 70   THR A HB   1 c 
ATOM   717   H  HG1  . THR A 1 64  ? 20.416  12.527  -15.624 0   69.42   ? 70   THR A HG1  1 c 
ATOM   718   H  HG21 . THR A 1 64  ? 19.985  14.583  -17.505 1   65.318  ? 70   THR A HG21 1 c 
ATOM   719   H  HG22 . THR A 1 64  ? 19.873  13.033  -17.826 1   65.193  ? 70   THR A HG22 1 c 
ATOM   720   H  HG23 . THR A 1 64  ? 20.919  13.932  -18.611 1   65.318  ? 70   THR A HG23 1 c 
ATOM   721   N  N    . ASN A 1 65  ? 23.416  10.883  -15.352 1   50.267  ? 71   ASN A N    1 ? 
ATOM   722   C  CA   . ASN A 1 65  ? 24.391  10.561  -14.322 1   49.41   ? 71   ASN A CA   1 ? 
ATOM   723   C  C    . ASN A 1 65  ? 25.781  10.306  -14.903 1   45.308  ? 71   ASN A C    1 ? 
ATOM   724   O  O    . ASN A 1 65  ? 26.76   10.383  -14.17  1   58.893  ? 71   ASN A O    1 ? 
ATOM   725   C  CB   . ASN A 1 65  ? 24.037  9.295   -13.558 1   57.184  ? 71   ASN A CB   1 ? 
ATOM   726   C  CG   . ASN A 1 65  ? 22.987  9.522   -12.5   1   51.944  ? 71   ASN A CG   1 ? 
ATOM   727   O  OD1  . ASN A 1 65  ? 23.157  10.372  -11.616 1   55.411  ? 71   ASN A OD1  1 ? 
ATOM   728   N  ND2  . ASN A 1 65  ? 21.93   8.73    -12.555 1   54.142  ? 71   ASN A ND2  1 ? 
ATOM   729   H  H    . ASN A 1 65  ? 22.749  10.288  -15.542 1   51.544  ? 71   ASN A H    1 c 
ATOM   730   H  HA   . ASN A 1 65  ? 24.437  11.305  -13.68  1   50.284  ? 71   ASN A HA   1 c 
ATOM   731   H  HB2  . ASN A 1 65  ? 23.716  8.622   -14.19  1   54.09   ? 71   ASN A HB2  1 c 
ATOM   732   H  HB3  . ASN A 1 65  ? 24.842  8.942   -13.13  1   54.067  ? 71   ASN A HB3  1 c 
ATOM   733   H  HD21 . ASN A 1 65  ? 21.269  8.841   -11.974 1   53.478  ? 71   ASN A HD21 1 c 
ATOM   734   H  HD22 . ASN A 1 65  ? 21.877  8.089   -13.166 1   53.491  ? 71   ASN A HD22 1 c 
ATOM   735   N  N    . LYS A 1 66  ? 25.853  9.948   -16.193 1   42.418  ? 72   LYS A N    1 ? 
ATOM   736   C  CA   . LYS A 1 66  ? 27.082  9.552   -16.865 1   44.832  ? 72   LYS A CA   1 ? 
ATOM   737   C  C    . LYS A 1 66  ? 28.204  10.543  -16.573 1   46.85   ? 72   LYS A C    1 ? 
ATOM   738   O  O    . LYS A 1 66  ? 29.3    10.152  -16.176 1   43.672  ? 72   LYS A O    1 ? 
ATOM   739   C  CB   . LYS A 1 66  ? 26.862  9.514   -18.383 1   45.104  ? 72   LYS A CB   1 ? 
ATOM   740   C  CG   . LYS A 1 66  ? 28.021  9.014   -19.2   1   42.783  ? 72   LYS A CG   1 ? 
ATOM   741   C  CD   . LYS A 1 66  ? 27.776  9.041   -20.703 1   46.142  ? 72   LYS A CD   1 ? 
ATOM   742   C  CE   . LYS A 1 66  ? 28.978  8.517   -21.425 1   47.034  ? 72   LYS A CE   1 ? 
ATOM   743   N  NZ   . LYS A 1 66  ? 28.834  8.514   -22.877 1   49.751  ? 72   LYS A NZ   1 ? 
ATOM   744   H  H    . LYS A 1 66  ? 25.082  9.941   -16.683 1   43.798  ? 72   LYS A H    1 c 
ATOM   745   H  HA   . LYS A 1 66  ? 27.347  8.653   -16.541 1   44.757  ? 72   LYS A HA   1 c 
ATOM   746   H  HB2  . LYS A 1 66  ? 26.087  8.943   -18.57  1   44.493  ? 72   LYS A HB2  1 c 
ATOM   747   H  HB3  . LYS A 1 66  ? 26.64   10.42   -18.688 1   44.518  ? 72   LYS A HB3  1 c 
ATOM   748   H  HG2  . LYS A 1 66  ? 28.809  9.564   -18.997 1   44.072  ? 72   LYS A HG2  1 c 
ATOM   749   H  HG3  . LYS A 1 66  ? 28.221  8.092   -18.925 1   44.06   ? 72   LYS A HG3  1 c 
ATOM   750   H  HD2  . LYS A 1 66  ? 26.997  8.483   -20.92  1   45.564  ? 72   LYS A HD2  1 c 
ATOM   751   H  HD3  . LYS A 1 66  ? 27.597  9.962   -20.992 1   45.564  ? 72   LYS A HD3  1 c 
ATOM   752   H  HE2  . LYS A 1 66  ? 29.752  9.059   -21.189 1   47.451  ? 72   LYS A HE2  1 c 
ATOM   753   H  HE3  . LYS A 1 66  ? 29.149  7.607   -21.13  1   47.427  ? 72   LYS A HE3  1 c 
ATOM   754   H  HZ1  . LYS A 1 66  ? 28.637  9.349   -23.168 1   48.899  ? 72   LYS A HZ1  1 c 
ATOM   755   H  HZ2  . LYS A 1 66  ? 28.167  7.949   -23.117 1   48.899  ? 72   LYS A HZ2  1 c 
ATOM   756   H  HZ3  . LYS A 1 66  ? 29.608  8.24    -23.261 1   48.899  ? 72   LYS A HZ3  1 c 
ATOM   757   N  N    . GLU A 1 67  ? 27.905  11.828  -16.767 1   47.387  ? 73   GLU A N    1 ? 
ATOM   758   C  CA   . GLU A 1 67  ? 28.937  12.838  -16.733 1   50.418  ? 73   GLU A CA   1 ? 
ATOM   759   C  C    . GLU A 1 67  ? 29.491  12.913  -15.326 1   44.905  ? 73   GLU A C    1 ? 
ATOM   760   O  O    . GLU A 1 67  ? 30.694  13.02   -15.205 1   44.913  ? 73   GLU A O    1 ? 
ATOM   761   C  CB   . GLU A 1 67  ? 28.536  14.229  -17.239 1   54.444  ? 73   GLU A CB   1 ? 
ATOM   762   C  CG   . GLU A 1 67  ? 28.525  14.355  -18.765 1   62.287  ? 73   GLU A CG   1 ? 
ATOM   763   C  CD   . GLU A 1 67  ? 29.696  13.794  -19.575 1   62.512  ? 73   GLU A CD   1 ? 
ATOM   764   O  OE1  . GLU A 1 67  ? 29.393  13.021  -20.52  1   60.558  ? 73   GLU A OE1  1 ? 
ATOM   765   O  OE2  . GLU A 1 67  ? 30.898  14.087  -19.29  1   58.376  ? 73   GLU A OE2  1 ? 
ATOM   766   H  H    . GLU A 1 67  ? 27.041  12.079  -16.928 1   47.866  ? 73   GLU A H    1 c 
ATOM   767   H  HA   . GLU A 1 67  ? 29.671  12.525  -17.319 1   49.436  ? 73   GLU A HA   1 c 
ATOM   768   H  HB2  . GLU A 1 67  ? 27.644  14.445  -16.895 1   55.268  ? 73   GLU A HB2  1 c 
ATOM   769   H  HB3  . GLU A 1 67  ? 29.161  14.888  -16.878 1   55.703  ? 73   GLU A HB3  1 c 
ATOM   770   H  HG2  . GLU A 1 67  ? 27.707  13.927  -19.097 1   60.381  ? 73   GLU A HG2  1 c 
ATOM   771   H  HG3  . GLU A 1 67  ? 28.442  15.307  -18.988 1   60.439  ? 73   GLU A HG3  1 c 
ATOM   772   N  N    . SER A 1 68  ? 28.634  12.81   -14.294 1   45.811  ? 74   SER A N    1 ? 
ATOM   773   C  CA   . SER A 1 68  ? 29.078  13.027  -12.929 1   36.09   ? 74   SER A CA   1 ? 
ATOM   774   C  C    . SER A 1 68  ? 29.984  11.886  -12.46  1   37.771  ? 74   SER A C    1 ? 
ATOM   775   O  O    . SER A 1 68  ? 30.947  12.121  -11.728 1   42.534  ? 74   SER A O    1 ? 
ATOM   776   C  CB   . SER A 1 68  ? 27.919  13.306  -11.985 1   41.447  ? 74   SER A CB   1 ? 
ATOM   777   O  OG   . SER A 1 68  ? 26.958  12.266  -12.024 1   45.595  ? 74   SER A OG   1 ? 
ATOM   778   H  H    . SER A 1 68  ? 27.757  12.604  -14.449 1   43.26   ? 74   SER A H    1 c 
ATOM   779   H  HA   . SER A 1 68  ? 29.637  13.845  -12.94  1   39.169  ? 74   SER A HA   1 c 
ATOM   780   H  HB2  . SER A 1 68  ? 28.26   13.398  -11.075 1   41.099  ? 74   SER A HB2  1 c 
ATOM   781   H  HB3  . SER A 1 68  ? 27.494  14.148  -12.236 1   41.099  ? 74   SER A HB3  1 c 
ATOM   782   H  HG   . SER A 1 68  ? 26.361  12.477  -11.486 0   46.42   ? 74   SER A HG   1 c 
ATOM   783   N  N    . LEU A 1 69  ? 29.718  10.669  -12.952 1   40.406  ? 75   LEU A N    1 ? 
ATOM   784   C  CA   . LEU A 1 69  ? 30.558  9.511   -12.678 1   41.347  ? 75   LEU A CA   1 ? 
ATOM   785   C  C    . LEU A 1 69  ? 31.928  9.674   -13.335 1   40.214  ? 75   LEU A C    1 ? 
ATOM   786   O  O    . LEU A 1 69  ? 32.925  9.24    -12.772 1   34.929  ? 75   LEU A O    1 ? 
ATOM   787   C  CB   . LEU A 1 69  ? 29.877  8.228   -13.15  1   36.201  ? 75   LEU A CB   1 ? 
ATOM   788   C  CG   . LEU A 1 69  ? 28.634  7.798   -12.356 1   39.685  ? 75   LEU A CG   1 ? 
ATOM   789   C  CD1  . LEU A 1 69  ? 28.07   6.516   -12.969 1   39.366  ? 75   LEU A CD1  1 ? 
ATOM   790   C  CD2  . LEU A 1 69  ? 28.876  7.588   -10.86  1   37.566  ? 75   LEU A CD2  1 ? 
ATOM   791   H  H    . LEU A 1 69  ? 28.976  10.555  -13.473 1   39.941  ? 75   LEU A H    1 c 
ATOM   792   H  HA   . LEU A 1 69  ? 30.695  9.459   -11.699 1   39.949  ? 75   LEU A HA   1 c 
ATOM   793   H  HB2  . LEU A 1 69  ? 29.618  8.347   -14.093 1   38.117  ? 75   LEU A HB2  1 c 
ATOM   794   H  HB3  . LEU A 1 69  ? 30.537  7.498   -13.112 1   38.116  ? 75   LEU A HB3  1 c 
ATOM   795   H  HG   . LEU A 1 69  ? 27.948  8.508   -12.455 1   38.565  ? 75   LEU A HG   1 c 
ATOM   796   H  HD11 . LEU A 1 69  ? 27.937  6.645   -13.923 1   39.543  ? 75   LEU A HD11 1 c 
ATOM   797   H  HD12 . LEU A 1 69  ? 27.22   6.301   -12.55  1   39.479  ? 75   LEU A HD12 1 c 
ATOM   798   H  HD13 . LEU A 1 69  ? 28.695  5.785   -12.827 1   39.479  ? 75   LEU A HD13 1 c 
ATOM   799   H  HD21 . LEU A 1 69  ? 29.092  8.439   -10.442 1   38.203  ? 75   LEU A HD21 1 c 
ATOM   800   H  HD22 . LEU A 1 69  ? 29.615  6.969   -10.734 1   38.183  ? 75   LEU A HD22 1 c 
ATOM   801   H  HD23 . LEU A 1 69  ? 28.074  7.222   -10.45  1   38.183  ? 75   LEU A HD23 1 c 
ATOM   802   N  N    . ILE A 1 70  ? 31.969  10.244  -14.545 1   39.106  ? 76   ILE A N    1 ? 
ATOM   803   C  CA   . ILE A 1 70  ? 33.244  10.394  -15.227 1   38.523  ? 76   ILE A CA   1 ? 
ATOM   804   C  C    . ILE A 1 70  ? 34.105  11.415  -14.511 1   37.68   ? 76   ILE A C    1 ? 
ATOM   805   O  O    . ILE A 1 70  ? 35.318  11.238  -14.461 1   46.095  ? 76   ILE A O    1 ? 
ATOM   806   C  CB   . ILE A 1 70  ? 33.06   10.755  -16.701 1   41.504  ? 76   ILE A CB   1 ? 
ATOM   807   C  CG1  . ILE A 1 70  ? 32.375  9.612   -17.414 1   45.335  ? 76   ILE A CG1  1 ? 
ATOM   808   C  CG2  . ILE A 1 70  ? 34.403  11.129  -17.334 1   44.252  ? 76   ILE A CG2  1 ? 
ATOM   809   C  CD1  . ILE A 1 70  ? 31.892  9.93    -18.819 1   49.355  ? 76   ILE A CD1  1 ? 
ATOM   810   H  H    . ILE A 1 70  ? 31.204  10.54   -14.947 1   39.343  ? 76   ILE A H    1 c 
ATOM   811   H  HA   . ILE A 1 70  ? 33.705  9.533   -15.189 1   39.061  ? 76   ILE A HA   1 c 
ATOM   812   H  HB   . ILE A 1 70  ? 32.473  11.535  -16.75  1   42.118  ? 76   ILE A HB   1 c 
ATOM   813   H  HG12 . ILE A 1 70  ? 32.998  8.859   -17.461 1   45.233  ? 76   ILE A HG12 1 c 
ATOM   814   H  HG13 . ILE A 1 70  ? 31.607  9.325   -16.88  1   45.16   ? 76   ILE A HG13 1 c 
ATOM   815   H  HG21 . ILE A 1 70  ? 34.304  11.191  -18.299 1   43.484  ? 76   ILE A HG21 1 c 
ATOM   816   H  HG22 . ILE A 1 70  ? 35.064  10.448  -17.122 1   43.437  ? 76   ILE A HG22 1 c 
ATOM   817   H  HG23 . ILE A 1 70  ? 34.701  11.987  -16.988 1   43.421  ? 76   ILE A HG23 1 c 
ATOM   818   H  HD11 . ILE A 1 70  ? 31.305  10.709  -18.794 1   48.121  ? 76   ILE A HD11 1 c 
ATOM   819   H  HD12 . ILE A 1 70  ? 31.399  9.165   -19.173 1   48.12   ? 76   ILE A HD12 1 c 
ATOM   820   H  HD13 . ILE A 1 70  ? 32.655  10.117  -19.397 1   48.08   ? 76   ILE A HD13 1 c 
ATOM   821   N  N    . ARG A 1 71  ? 33.499  12.462  -13.936 1   42.53   ? 77   ARG A N    1 ? 
ATOM   822   C  CA   . ARG A 1 71  ? 34.294  13.525  -13.325 1   45.353  ? 77   ARG A CA   1 ? 
ATOM   823   C  C    . ARG A 1 71  ? 34.818  13.039  -11.986 1   41.343  ? 77   ARG A C    1 ? 
ATOM   824   O  O    . ARG A 1 71  ? 35.819  13.53   -11.487 1   41.642  ? 77   ARG A O    1 ? 
ATOM   825   C  CB   . ARG A 1 71  ? 33.524  14.839  -13.168 1   48.634  ? 77   ARG A CB   1 ? 
ATOM   826   C  CG   . ARG A 1 71  ? 33.33   15.513  -14.522 1   60.404  ? 77   ARG A CG   1 ? 
ATOM   827   C  CD   . ARG A 1 71  ? 32.942  16.98   -14.396 1   72.619  ? 77   ARG A CD   1 ? 
ATOM   828   N  NE   . ARG A 1 71  ? 31.634  17.117  -13.746 1   90.64   ? 77   ARG A NE   1 ? 
ATOM   829   C  CZ   . ARG A 1 71  ? 30.452  16.836  -14.307 1   92.846  ? 77   ARG A CZ   1 ? 
ATOM   830   N  NH1  . ARG A 1 71  ? 30.368  16.629  -15.616 1   95.814  ? 77   ARG A NH1  1 ? 
ATOM   831   N  NH2  . ARG A 1 71  ? 29.359  16.796  -13.552 1   75.656  ? 77   ARG A NH2  1 ? 
ATOM   832   H  H    . ARG A 1 71  ? 32.587  12.523  -13.927 1   41.887  ? 77   ARG A H    1 c 
ATOM   833   H  HA   . ARG A 1 71  ? 35.073  13.701  -13.912 1   44.728  ? 77   ARG A HA   1 c 
ATOM   834   H  HB2  . ARG A 1 71  ? 32.647  14.66   -12.765 1   50.291  ? 77   ARG A HB2  1 c 
ATOM   835   H  HB3  . ARG A 1 71  ? 34.019  15.442  -12.573 1   50.248  ? 77   ARG A HB3  1 c 
ATOM   836   H  HG2  . ARG A 1 71  ? 34.163  15.449  -15.038 1   59.813  ? 77   ARG A HG2  1 c 
ATOM   837   H  HG3  . ARG A 1 71  ? 32.631  15.038  -15.021 1   60.239  ? 77   ARG A HG3  1 c 
ATOM   838   H  HD2  . ARG A 1 71  ? 33.617  17.452  -13.868 1   73.447  ? 77   ARG A HD2  1 c 
ATOM   839   H  HD3  . ARG A 1 71  ? 32.908  17.389  -15.285 1   73.53   ? 77   ARG A HD3  1 c 
ATOM   840   H  HE   . ARG A 1 71  ? 31.624  17.408  -12.925 1   86.445  ? 77   ARG A HE   1 c 
ATOM   841   H  HH11 . ARG A 1 71  ? 30.931  16.079  -16.018 1   93.581  ? 77   ARG A HH11 1 c 
ATOM   842   H  HH12 . ARG A 1 71  ? 29.744  17.046  -16.083 1   94.181  ? 77   ARG A HH12 1 c 
ATOM   843   H  HH21 . ARG A 1 71  ? 29.432  16.765  -12.669 1   80.728  ? 77   ARG A HH21 1 c 
ATOM   844   H  HH22 . ARG A 1 71  ? 28.561  16.798  -13.936 1   80.717  ? 77   ARG A HH22 1 c 
ATOM   845   N  N    . ALA A 1 72  ? 34.116  12.057  -11.402 1   47.836  ? 78   ALA A N    1 ? 
ATOM   846   C  CA   . ALA A 1 72  ? 34.549  11.43   -10.167 1   40.224  ? 78   ALA A CA   1 ? 
ATOM   847   C  C    . ALA A 1 72  ? 35.788  10.577  -10.435 1   37.438  ? 78   ALA A C    1 ? 
ATOM   848   O  O    . ALA A 1 72  ? 36.674  10.488  -9.594  1   40.519  ? 78   ALA A O    1 ? 
ATOM   849   C  CB   . ALA A 1 72  ? 33.41   10.62   -9.591  1   43.431  ? 78   ALA A CB   1 ? 
ATOM   850   H  H    . ALA A 1 72  ? 33.331  11.78   -11.779 1   44.352  ? 78   ALA A H    1 c 
ATOM   851   H  HA   . ALA A 1 72  ? 34.798  12.148  -9.521  1   41.646  ? 78   ALA A HA   1 c 
ATOM   852   H  HB1  . ALA A 1 72  ? 32.648  11.2    -9.423  1   42.444  ? 78   ALA A HB1  1 c 
ATOM   853   H  HB2  . ALA A 1 72  ? 33.151  9.925   -10.22  1   42.409  ? 78   ALA A HB2  1 c 
ATOM   854   H  HB3  . ALA A 1 72  ? 33.69   10.208  -8.756  1   42.444  ? 78   ALA A HB3  1 c 
ATOM   855   N  N    . GLY A 1 73  ? 35.842  9.945   -11.611 1   38.209  ? 79   GLY A N    1 ? 
ATOM   856   C  CA   . GLY A 1 73  ? 37.001  9.163   -12.014 1   45.106  ? 79   GLY A CA   1 ? 
ATOM   857   C  C    . GLY A 1 73  ? 38.213  10.039  -12.362 1   47.457  ? 79   GLY A C    1 ? 
ATOM   858   O  O    . GLY A 1 73  ? 39.36   9.632   -12.149 1   42.337  ? 79   GLY A O    1 ? 
ATOM   859   H  H    . GLY A 1 73  ? 35.128  9.992   -12.179 1   39.529  ? 79   GLY A H    1 c 
ATOM   860   H  HA2  . GLY A 1 73  ? 37.242  8.547   -11.283 1   43.763  ? 79   GLY A HA2  1 c 
ATOM   861   H  HA3  . GLY A 1 73  ? 36.761  8.619   -12.797 1   43.705  ? 79   GLY A HA3  1 c 
ATOM   862   N  N    . GLU A 1 74  ? 37.961  11.224  -12.92  1   45.155  ? 80   GLU A N    1 ? 
ATOM   863   C  CA   . GLU A 1 74  ? 39.039  12.122  -13.311 1   46.434  ? 80   GLU A CA   1 ? 
ATOM   864   C  C    . GLU A 1 74  ? 39.763  12.58   -12.054 1   39.656  ? 80   GLU A C    1 ? 
ATOM   865   O  O    . GLU A 1 74  ? 40.976  12.615  -12.034 1   48.983  ? 80   GLU A O    1 ? 
ATOM   866   C  CB   . GLU A 1 74  ? 38.551  13.315  -14.131 1   37.872  ? 80   GLU A CB   1 ? 
ATOM   867   C  CG   . GLU A 1 74  ? 38.075  12.917  -15.526 1   40.986  ? 80   GLU A CG   1 ? 
ATOM   868   C  CD   . GLU A 1 74  ? 37.29   13.974  -16.316 1   43.866  ? 80   GLU A CD   1 ? 
ATOM   869   O  OE1  . GLU A 1 74  ? 37.072  13.76   -17.528 1   48.89   ? 80   GLU A OE1  1 ? 
ATOM   870   O  OE2  . GLU A 1 74  ? 36.887  14.999  -15.733 1   41.679  ? 80   GLU A OE2  1 ? 
ATOM   871   H  H    . GLU A 1 74  ? 37.096  11.481  -13.067 1   45.857  ? 80   GLU A H    1 c 
ATOM   872   H  HA   . GLU A 1 74  ? 39.679  11.609  -13.868 1   43.281  ? 80   GLU A HA   1 c 
ATOM   873   H  HB2  . GLU A 1 74  ? 37.816  13.749  -13.65  1   40.398  ? 80   GLU A HB2  1 c 
ATOM   874   H  HB3  . GLU A 1 74  ? 39.28   13.965  -14.213 1   40.387  ? 80   GLU A HB3  1 c 
ATOM   875   H  HG2  . GLU A 1 74  ? 38.858  12.661  -16.059 1   40.89   ? 80   GLU A HG2  1 c 
ATOM   876   H  HG3  . GLU A 1 74  ? 37.514  12.118  -15.447 1   40.929  ? 80   GLU A HG3  1 c 
ATOM   877   N  N    . LYS A 1 75  ? 39.013  12.845  -10.98  1   47.033  ? 81   LYS A N    1 ? 
ATOM   878   C  CA   . LYS A 1 75  ? 39.624  13.183  -9.714  1   46.43   ? 81   LYS A CA   1 ? 
ATOM   879   C  C    . LYS A 1 75  ? 40.572  12.067  -9.291  1   44.756  ? 81   LYS A C    1 ? 
ATOM   880   O  O    . LYS A 1 75  ? 41.603  12.372  -8.721  1   49.439  ? 81   LYS A O    1 ? 
ATOM   881   C  CB   . LYS A 1 75  ? 38.62   13.53   -8.615  1   58.322  ? 81   LYS A CB   1 ? 
ATOM   882   C  CG   . LYS A 1 75  ? 38.096  14.953  -8.61   1   67.062  ? 81   LYS A CG   1 ? 
ATOM   883   C  CD   . LYS A 1 75  ? 37.182  15.229  -7.423  1   78.6    ? 81   LYS A CD   1 ? 
ATOM   884   C  CE   . LYS A 1 75  ? 36.423  16.517  -7.588  1   91.707  ? 81   LYS A CE   1 ? 
ATOM   885   N  NZ   . LYS A 1 75  ? 35.084  16.417  -7.004  1   99.019  ? 81   LYS A NZ   1 ? 
ATOM   886   H  H    . LYS A 1 75  ? 38.101  12.824  -11.042 1   45.192  ? 81   LYS A H    1 c 
ATOM   887   H  HA   . LYS A 1 75  ? 40.172  13.996  -9.861  1   48.202  ? 81   LYS A HA   1 c 
ATOM   888   H  HB2  . LYS A 1 75  ? 37.854  12.923  -8.693  1   57.06   ? 81   LYS A HB2  1 c 
ATOM   889   H  HB3  . LYS A 1 75  ? 39.043  13.36   -7.746  1   57.018  ? 81   LYS A HB3  1 c 
ATOM   890   H  HG2  . LYS A 1 75  ? 38.859  15.571  -8.581  1   67.357  ? 81   LYS A HG2  1 c 
ATOM   891   H  HG3  . LYS A 1 75  ? 37.604  15.111  -9.444  1   67.47   ? 81   LYS A HG3  1 c 
ATOM   892   H  HD2  . LYS A 1 75  ? 36.544  14.488  -7.329  1   78.784  ? 81   LYS A HD2  1 c 
ATOM   893   H  HD3  . LYS A 1 75  ? 37.721  15.276  -6.604  1   78.61   ? 81   LYS A HD3  1 c 
ATOM   894   H  HE2  . LYS A 1 75  ? 36.907  17.24   -7.149  1   90.105  ? 81   LYS A HE2  1 c 
ATOM   895   H  HE3  . LYS A 1 75  ? 36.339  16.737  -8.534  1   89.838  ? 81   LYS A HE3  1 c 
ATOM   896   H  HZ1  . LYS A 1 75  ? 35.146  16.173  -6.134  1   96.562  ? 81   LYS A HZ1  1 c 
ATOM   897   H  HZ2  . LYS A 1 75  ? 34.6    15.796  -7.454  1   96.543  ? 81   LYS A HZ2  1 c 
ATOM   898   H  HZ3  . LYS A 1 75  ? 34.663  17.217  -7.06   1   96.649  ? 81   LYS A HZ3  1 c 
ATOM   899   N  N    . MET A 1 76  ? 40.259  10.796  -9.581  1   37.631  ? 82   MET A N    1 ? 
ATOM   900   C  CA   . MET A 1 76  ? 41.077  9.692   -9.088  1   39.459  ? 82   MET A CA   1 ? 
ATOM   901   C  C    . MET A 1 76  ? 42.234  9.364   -10.032 1   40.456  ? 82   MET A C    1 ? 
ATOM   902   O  O    . MET A 1 76  ? 43.039  8.48    -9.738  1   37.851  ? 82   MET A O    1 ? 
ATOM   903   C  CB   . MET A 1 76  ? 40.223  8.431   -8.887  1   38.187  ? 82   MET A CB   1 ? 
ATOM   904   C  CG   . MET A 1 76  ? 39.123  8.589   -7.844  1   37.478  ? 82   MET A CG   1 ? 
ATOM   905   S  SD   . MET A 1 76  ? 39.7    9.147   -6.223  1   41.087  ? 82   MET A SD   1 ? 
ATOM   906   C  CE   . MET A 1 76  ? 39.121  10.811  -5.867  1   51.33   ? 82   MET A CE   1 ? 
ATOM   907   H  H    . MET A 1 76  ? 39.514  10.61   -10.075 1   39.763  ? 82   MET A H    1 c 
ATOM   908   H  HA   . MET A 1 76  ? 41.463  9.962   -8.218  1   39.109  ? 82   MET A HA   1 c 
ATOM   909   H  HB2  . MET A 1 76  ? 39.813  8.192   -9.745  1   38.161  ? 82   MET A HB2  1 c 
ATOM   910   H  HB3  . MET A 1 76  ? 40.81   7.692   -8.619  1   38.287  ? 82   MET A HB3  1 c 
ATOM   911   H  HG2  . MET A 1 76  ? 38.464  9.231   -8.173  1   38.323  ? 82   MET A HG2  1 c 
ATOM   912   H  HG3  . MET A 1 76  ? 38.668  7.731   -7.731  1   38.313  ? 82   MET A HG3  1 c 
ATOM   913   H  HE1  . MET A 1 76  ? 39.471  11.099  -5.004  1   48.565  ? 82   MET A HE1  1 c 
ATOM   914   H  HE2  . MET A 1 76  ? 39.432  11.418  -6.564  1   48.608  ? 82   MET A HE2  1 c 
ATOM   915   H  HE3  . MET A 1 76  ? 38.146  10.817  -5.842  1   48.564  ? 82   MET A HE3  1 c 
ATOM   916   N  N    . LEU A 1 77  ? 42.31   10.054  -11.178 1   49.327  ? 83   LEU A N    1 ? 
ATOM   917   C  CA   . LEU A 1 77  ? 43.38   9.816   -12.14  1   46.337  ? 83   LEU A CA   1 ? 
ATOM   918   C  C    . LEU A 1 77  ? 44.726  10.092  -11.473 1   40.653  ? 83   LEU A C    1 ? 
ATOM   919   O  O    . LEU A 1 77  ? 45.681  9.378   -11.726 1   41.925  ? 83   LEU A O    1 ? 
ATOM   920   C  CB   . LEU A 1 77  ? 43.202  10.616  -13.424 1   44.322  ? 83   LEU A CB   1 ? 
ATOM   921   C  CG   . LEU A 1 77  ? 42.204  10.043  -14.435 1   47.073  ? 83   LEU A CG   1 ? 
ATOM   922   C  CD1  . LEU A 1 77  ? 41.996  11.029  -15.567 1   47.865  ? 83   LEU A CD1  1 ? 
ATOM   923   C  CD2  . LEU A 1 77  ? 42.686  8.717   -14.971 1   45.013  ? 83   LEU A CD2  1 ? 
ATOM   924   H  H    . LEU A 1 77  ? 41.677  10.682  -11.374 1   46.193  ? 83   LEU A H    1 c 
ATOM   925   H  HA   . LEU A 1 77  ? 43.36   8.853   -12.367 1   45.321  ? 83   LEU A HA   1 c 
ATOM   926   H  HB2  . LEU A 1 77  ? 42.915  11.527  -13.183 1   45.411  ? 83   LEU A HB2  1 c 
ATOM   927   H  HB3  . LEU A 1 77  ? 44.08   10.691  -13.864 1   45.368  ? 83   LEU A HB3  1 c 
ATOM   928   H  HG   . LEU A 1 77  ? 41.336  9.902   -13.976 1   46.271  ? 83   LEU A HG   1 c 
ATOM   929   H  HD11 . LEU A 1 77  ? 41.665  11.87   -15.21  1   47.629  ? 83   LEU A HD11 1 c 
ATOM   930   H  HD12 . LEU A 1 77  ? 41.35   10.669  -16.197 1   47.629  ? 83   LEU A HD12 1 c 
ATOM   931   H  HD13 . LEU A 1 77  ? 42.841  11.183  -16.024 1   47.629  ? 83   LEU A HD13 1 c 
ATOM   932   H  HD21 . LEU A 1 77  ? 42.651  8.047   -14.268 1   45.604  ? 83   LEU A HD21 1 c 
ATOM   933   H  HD22 . LEU A 1 77  ? 43.6    8.806   -15.288 1   45.603  ? 83   LEU A HD22 1 c 
ATOM   934   H  HD23 . LEU A 1 77  ? 42.115  8.439   -15.708 1   45.563  ? 83   LEU A HD23 1 c 
ATOM   935   N  N    . ASN A 1 78  ? 44.762  11.035  -10.54  1   38.203  ? 84   ASN A N    1 ? 
ATOM   936   C  CA   . ASN A 1 78  ? 45.998  11.325  -9.828  1   51.857  ? 84   ASN A CA   1 ? 
ATOM   937   C  C    . ASN A 1 78  ? 45.902  10.908  -8.361  1   47.154  ? 84   ASN A C    1 ? 
ATOM   938   O  O    . ASN A 1 78  ? 46.649  11.434  -7.56   1   49.457  ? 84   ASN A O    1 ? 
ATOM   939   C  CB   . ASN A 1 78  ? 46.378  12.804  -9.878  1   50.496  ? 84   ASN A CB   1 ? 
ATOM   940   C  CG   . ASN A 1 78  ? 46.759  13.266  -11.269 1   61.663  ? 84   ASN A CG   1 ? 
ATOM   941   O  OD1  . ASN A 1 78  ? 47.615  12.671  -11.942 1   62.725  ? 84   ASN A OD1  1 ? 
ATOM   942   N  ND2  . ASN A 1 78  ? 46.127  14.335  -11.726 1   69.001  ? 84   ASN A ND2  1 ? 
ATOM   943   H  H    . ASN A 1 78  ? 44.014  11.523  -10.348 1   41.62   ? 84   ASN A H    1 c 
ATOM   944   H  HA   . ASN A 1 78  ? 46.729  10.818  -10.247 1   47.754  ? 84   ASN A HA   1 c 
ATOM   945   H  HB2  . ASN A 1 78  ? 45.624  13.337  -9.558  1   53.353  ? 84   ASN A HB2  1 c 
ATOM   946   H  HB3  . ASN A 1 78  ? 47.134  12.962  -9.278  1   53.169  ? 84   ASN A HB3  1 c 
ATOM   947   H  HD21 . ASN A 1 78  ? 46.216  14.568  -12.578 1   66.559  ? 84   ASN A HD21 1 c 
ATOM   948   H  HD22 . ASN A 1 78  ? 45.617  14.821  -11.186 1   66.375  ? 84   ASN A HD22 1 c 
ATOM   949   N  N    . TYR A 1 79  ? 45.034  9.947   -8.006  1   40.128  ? 85   TYR A N    1 ? 
ATOM   950   C  CA   . TYR A 1 79  ? 44.921  9.506   -6.624  1   34.781  ? 85   TYR A CA   1 ? 
ATOM   951   C  C    . TYR A 1 79  ? 46.195  8.756   -6.223  1   33.915  ? 85   TYR A C    1 ? 
ATOM   952   O  O    . TYR A 1 79  ? 46.631  7.871   -6.931  1   35.894  ? 85   TYR A O    1 ? 
ATOM   953   C  CB   . TYR A 1 79  ? 43.662  8.646   -6.415  1   37.023  ? 85   TYR A CB   1 ? 
ATOM   954   C  CG   . TYR A 1 79  ? 43.603  8.153   -4.974  1   32.009  ? 85   TYR A CG   1 ? 
ATOM   955   C  CD1  . TYR A 1 79  ? 43.212  9       -3.945  1   30.371  ? 85   TYR A CD1  1 ? 
ATOM   956   C  CD2  . TYR A 1 79  ? 44.03   6.867   -4.634  1   33.931  ? 85   TYR A CD2  1 ? 
ATOM   957   C  CE1  . TYR A 1 79  ? 43.206  8.58    -2.618  1   29.932  ? 85   TYR A CE1  1 ? 
ATOM   958   C  CE2  . TYR A 1 79  ? 44.01   6.431   -3.311  1   33.198  ? 85   TYR A CE2  1 ? 
ATOM   959   C  CZ   . TYR A 1 79  ? 43.623  7.297   -2.301  1   28.394  ? 85   TYR A CZ   1 ? 
ATOM   960   O  OH   . TYR A 1 79  ? 43.605  6.837   -1.007  1   31.659  ? 85   TYR A OH   1 ? 
ATOM   961   H  H    . TYR A 1 79  ? 44.513  9.548   -8.64   1   40.343  ? 85   TYR A H    1 c 
ATOM   962   H  HA   . TYR A 1 79  ? 44.841  10.313  -6.05   1   36.133  ? 85   TYR A HA   1 c 
ATOM   963   H  HB2  . TYR A 1 79  ? 42.866  9.188   -6.61   1   35.344  ? 85   TYR A HB2  1 c 
ATOM   964   H  HB3  . TYR A 1 79  ? 43.69   7.877   -7.026  1   35.324  ? 85   TYR A HB3  1 c 
ATOM   965   H  HD1  . TYR A 1 79  ? 42.946  9.882   -4.149  1   30.693  ? 85   TYR A HD1  1 c 
ATOM   966   H  HD2  . TYR A 1 79  ? 44.312  6.275   -5.313  1   33.258  ? 85   TYR A HD2  1 c 
ATOM   967   H  HE1  . TYR A 1 79  ? 42.923  9.166   -1.937  1   30.029  ? 85   TYR A HE1  1 c 
ATOM   968   H  HE2  . TYR A 1 79  ? 44.29   5.557   -3.099  1   32.212  ? 85   TYR A HE2  1 c 
ATOM   969   H  HH   . TYR A 1 79  ? 42.844  6.486   -0.826  0   32.47   ? 85   TYR A HH   1 c 
ATOM   970   N  N    . GLU A 1 80  ? 46.751  9.049   -5.038  1   38.599  ? 86   GLU A N    1 ? 
ATOM   971   C  CA   . GLU A 1 80  ? 47.944  8.384   -4.526  1   39.01   ? 86   GLU A CA   1 ? 
ATOM   972   C  C    . GLU A 1 80  ? 47.558  7.338   -3.478  1   38.164  ? 86   GLU A C    1 ? 
ATOM   973   O  O    . GLU A 1 80  ? 47.088  7.671   -2.393  1   34.862  ? 86   GLU A O    1 ? 
ATOM   974   C  CB   . GLU A 1 80  ? 48.787  9.506   -3.933  1   39.613  ? 86   GLU A CB   1 ? 
ATOM   975   C  CG   . GLU A 1 80  ? 50.151  9.121   -3.38   1   48.596  ? 86   GLU A CG   1 ? 
ATOM   976   C  CD   . GLU A 1 80  ? 50.727  10.345  -2.665  1   55.894  ? 86   GLU A CD   1 ? 
ATOM   977   O  OE1  . GLU A 1 80  ? 51.073  11.306  -3.372  1   66.214  ? 86   GLU A OE1  1 ? 
ATOM   978   O  OE2  . GLU A 1 80  ? 50.747  10.4    -1.419  1   60.668  ? 86   GLU A OE2  1 ? 
ATOM   979   H  H    . GLU A 1 80  ? 46.36   9.693   -4.52   1   37.528  ? 86   GLU A H    1 c 
ATOM   980   H  HA   . GLU A 1 80  ? 48.426  7.951   -5.275  1   38.782  ? 86   GLU A HA   1 c 
ATOM   981   H  HB2  . GLU A 1 80  ? 48.919  10.189  -4.623  1   41.455  ? 86   GLU A HB2  1 c 
ATOM   982   H  HB3  . GLU A 1 80  ? 48.278  9.92    -3.205  1   41.404  ? 86   GLU A HB3  1 c 
ATOM   983   H  HG2  . GLU A 1 80  ? 50.061  8.381   -2.742  1   47.847  ? 86   GLU A HG2  1 c 
ATOM   984   H  HG3  . GLU A 1 80  ? 50.749  8.853   -4.109  1   47.937  ? 86   GLU A HG3  1 c 
ATOM   985   N  N    . TRP A 1 81  ? 47.81   6.074   -3.801  1   33.444  ? 87   TRP A N    1 ? 
ATOM   986   C  CA   . TRP A 1 81  ? 47.509  4.971   -2.911  1   40.07   ? 87   TRP A CA   1 ? 
ATOM   987   C  C    . TRP A 1 81  ? 48.302  5.125   -1.617  1   39.478  ? 87   TRP A C    1 ? 
ATOM   988   O  O    . TRP A 1 81  ? 49.489  5.456   -1.665  1   40.812  ? 87   TRP A O    1 ? 
ATOM   989   C  CB   . TRP A 1 81  ? 47.81   3.655   -3.641  1   44.64   ? 87   TRP A CB   1 ? 
ATOM   990   C  CG   . TRP A 1 81  ? 47.13   3.643   -4.983  1   43.393  ? 87   TRP A CG   1 ? 
ATOM   991   C  CD1  . TRP A 1 81  ? 47.644  4.087   -6.168  1   39.382  ? 87   TRP A CD1  1 ? 
ATOM   992   C  CD2  . TRP A 1 81  ? 45.742  3.345   -5.233  1   37.989  ? 87   TRP A CD2  1 ? 
ATOM   993   N  NE1  . TRP A 1 81  ? 46.712  3.964   -7.158  1   36.234  ? 87   TRP A NE1  1 ? 
ATOM   994   C  CE2  . TRP A 1 81  ? 45.526  3.555   -6.61   1   35.684  ? 87   TRP A CE2  1 ? 
ATOM   995   C  CE3  . TRP A 1 81  ? 44.68   2.918   -4.434  1   35.545  ? 87   TRP A CE3  1 ? 
ATOM   996   C  CZ2  . TRP A 1 81  ? 44.286  3.352   -7.214  1   37.08   ? 87   TRP A CZ2  1 ? 
ATOM   997   C  CZ3  . TRP A 1 81  ? 43.449  2.751   -5.022  1   38.011  ? 87   TRP A CZ3  1 ? 
ATOM   998   C  CH2  . TRP A 1 81  ? 43.254  2.968   -6.391  1   38.865  ? 87   TRP A CH2  1 ? 
ATOM   999   H  H    . TRP A 1 81  ? 48.22   5.898   -4.598  1   36.143  ? 87   TRP A H    1 c 
ATOM   1000  H  HA   . TRP A 1 81  ? 46.539  4.997   -2.697  1   39.245  ? 87   TRP A HA   1 c 
ATOM   1001  H  HB2  . TRP A 1 81  ? 48.78   3.574   -3.767  1   43.283  ? 87   TRP A HB2  1 c 
ATOM   1002  H  HB3  . TRP A 1 81  ? 47.478  2.907   -3.1    1   43.283  ? 87   TRP A HB3  1 c 
ATOM   1003  H  HD1  . TRP A 1 81  ? 48.545  4.328   -6.313  1   39.439  ? 87   TRP A HD1  1 c 
ATOM   1004  H  HE1  . TRP A 1 81  ? 46.836  4.175   -7.996  1   36.884  ? 87   TRP A HE1  1 c 
ATOM   1005  H  HE3  . TRP A 1 81  ? 44.798  2.782   -3.509  1   36.706  ? 87   TRP A HE3  1 c 
ATOM   1006  H  HZ2  . TRP A 1 81  ? 44.154  3.514   -8.132  1   37.161  ? 87   TRP A HZ2  1 c 
ATOM   1007  H  HZ3  . TRP A 1 81  ? 42.724  2.461   -4.494  1   37.483  ? 87   TRP A HZ3  1 c 
ATOM   1008  H  HH2  . TRP A 1 81  ? 42.402  2.819   -6.763  1   38.203  ? 87   TRP A HH2  1 c 
ATOM   1009  N  N    . LYS A 1 82  ? 47.631  4.897   -0.474  1   35.676  ? 88   LYS A N    1 ? 
ATOM   1010  C  CA   . LYS A 1 82  ? 48.256  5.098   0.823   1   37.596  ? 88   LYS A CA   1 ? 
ATOM   1011  C  C    . LYS A 1 82  ? 48.604  3.759   1.456   1   34.19   ? 88   LYS A C    1 ? 
ATOM   1012  O  O    . LYS A 1 82  ? 47.793  2.819   1.475   1   36.106  ? 88   LYS A O    1 ? 
ATOM   1013  C  CB   . LYS A 1 82  ? 47.369  5.932   1.75    1   41.613  ? 88   LYS A CB   1 ? 
ATOM   1014  C  CG   . LYS A 1 82  ? 47.229  7.382   1.31    1   47.812  ? 88   LYS A CG   1 ? 
ATOM   1015  C  CD   . LYS A 1 82  ? 45.836  7.901   1.639   1   58.861  ? 88   LYS A CD   1 ? 
ATOM   1016  C  CE   . LYS A 1 82  ? 45.421  9.07    0.78    1   65.876  ? 88   LYS A CE   1 ? 
ATOM   1017  N  NZ   . LYS A 1 82  ? 43.972  9.192   0.633   1   50.902  ? 88   LYS A NZ   1 ? 
ATOM   1018  H  H    . LYS A 1 82  ? 46.765  4.608   -0.507  1   36.997  ? 88   LYS A H    1 c 
ATOM   1019  H  HA   . LYS A 1 82  ? 49.096  5.604   0.684   1   37.212  ? 88   LYS A HA   1 c 
ATOM   1020  H  HB2  . LYS A 1 82  ? 46.478  5.523   1.789   1   42.164  ? 88   LYS A HB2  1 c 
ATOM   1021  H  HB3  . LYS A 1 82  ? 47.748  5.914   2.655   1   41.973  ? 88   LYS A HB3  1 c 
ATOM   1022  H  HG2  . LYS A 1 82  ? 47.902  7.927   1.775   1   48.565  ? 88   LYS A HG2  1 c 
ATOM   1023  H  HG3  . LYS A 1 82  ? 47.386  7.443   0.343   1   48.572  ? 88   LYS A HG3  1 c 
ATOM   1024  H  HD2  . LYS A 1 82  ? 45.184  7.176   1.524   1   57.353  ? 88   LYS A HD2  1 c 
ATOM   1025  H  HD3  . LYS A 1 82  ? 45.82   8.174   2.58    1   57.5    ? 88   LYS A HD3  1 c 
ATOM   1026  H  HE2  . LYS A 1 82  ? 45.765  9.892   1.173   1   60.352  ? 88   LYS A HE2  1 c 
ATOM   1027  H  HE3  . LYS A 1 82  ? 45.814  8.977   -0.106  1   60.213  ? 88   LYS A HE3  1 c 
ATOM   1028  H  HZ1  . LYS A 1 82  ? 43.584  9.245   1.449   1   54.573  ? 88   LYS A HZ1  1 c 
ATOM   1029  H  HZ2  . LYS A 1 82  ? 43.659  8.466   0.198   1   53.712  ? 88   LYS A HZ2  1 c 
ATOM   1030  H  HZ3  . LYS A 1 82  ? 43.771  9.937   0.157   1   54.534  ? 88   LYS A HZ3  1 c 
ATOM   1031  N  N    . VAL A 1 83  ? 49.825  3.704   1.992   1   30.44   ? 89   VAL A N    1 ? 
ATOM   1032  C  CA   . VAL A 1 83  ? 50.242  2.562   2.776   1   35.295  ? 89   VAL A CA   1 ? 
ATOM   1033  C  C    . VAL A 1 83  ? 49.43   2.638   4.067   1   33.075  ? 89   VAL A C    1 ? 
ATOM   1034  O  O    . VAL A 1 83  ? 49.271  3.722   4.614   1   36.044  ? 89   VAL A O    1 ? 
ATOM   1035  C  CB   . VAL A 1 83  ? 51.767  2.539   3.017   1   32.128  ? 89   VAL A CB   1 ? 
ATOM   1036  C  CG1  . VAL A 1 83  ? 52.183  1.489   4.067   1   34.149  ? 89   VAL A CG1  1 ? 
ATOM   1037  C  CG2  . VAL A 1 83  ? 52.527  2.267   1.726   1   35.476  ? 89   VAL A CG2  1 ? 
ATOM   1038  H  H    . VAL A 1 83  ? 50.412  4.393   1.865   1   32.442  ? 89   VAL A H    1 c 
ATOM   1039  H  HA   . VAL A 1 83  ? 49.991  1.749   2.295   1   33.322  ? 89   VAL A HA   1 c 
ATOM   1040  H  HB   . VAL A 1 83  ? 52.027  3.43    3.349   1   33.67   ? 89   VAL A HB   1 c 
ATOM   1041  H  HG11 . VAL A 1 83  ? 51.797  0.627   3.836   1   33.551  ? 89   VAL A HG11 1 c 
ATOM   1042  H  HG12 . VAL A 1 83  ? 51.866  1.761   4.945   1   33.549  ? 89   VAL A HG12 1 c 
ATOM   1043  H  HG13 . VAL A 1 83  ? 53.152  1.414   4.085   1   33.564  ? 89   VAL A HG13 1 c 
ATOM   1044  H  HG21 . VAL A 1 83  ? 53.482  2.262   1.906   1   34.448  ? 89   VAL A HG21 1 c 
ATOM   1045  H  HG22 . VAL A 1 83  ? 52.325  2.963   1.077   1   34.453  ? 89   VAL A HG22 1 c 
ATOM   1046  H  HG23 . VAL A 1 83  ? 52.261  1.404   1.367   1   34.453  ? 89   VAL A HG23 1 c 
ATOM   1047  N  N    . ILE A 1 84  ? 48.838  1.517   4.491   1   32.598  ? 90   ILE A N    1 ? 
ATOM   1048  C  CA   . ILE A 1 84  ? 48.265  1.435   5.829   1   33.947  ? 90   ILE A CA   1 ? 
ATOM   1049  C  C    . ILE A 1 84  ? 49.337  0.841   6.736   1   32.915  ? 90   ILE A C    1 ? 
ATOM   1050  O  O    . ILE A 1 84  ? 49.725  -0.315  6.575   1   34.27   ? 90   ILE A O    1 ? 
ATOM   1051  C  CB   . ILE A 1 84  ? 46.942  0.634   5.775   1   41.486  ? 90   ILE A CB   1 ? 
ATOM   1052  C  CG1  . ILE A 1 84  ? 46.03   1.282   4.745   1   41.806  ? 90   ILE A CG1  1 ? 
ATOM   1053  C  CG2  . ILE A 1 84  ? 46.244  0.546   7.14    1   38.562  ? 90   ILE A CG2  1 ? 
ATOM   1054  C  CD1  . ILE A 1 84  ? 45.027  0.322   4.167   1   53.433  ? 90   ILE A CD1  1 ? 
ATOM   1055  H  H    . ILE A 1 84  ? 48.788  0.789   3.939   1   33.099  ? 90   ILE A H    1 c 
ATOM   1056  H  HA   . ILE A 1 84  ? 48.06   2.339   6.136   1   34.69   ? 90   ILE A HA   1 c 
ATOM   1057  H  HB   . ILE A 1 84  ? 47.147  -0.274  5.474   1   39.569  ? 90   ILE A HB   1 c 
ATOM   1058  H  HG12 . ILE A 1 84  ? 45.552  2.025   5.166   1   44.064  ? 90   ILE A HG12 1 c 
ATOM   1059  H  HG13 . ILE A 1 84  ? 46.573  1.646   4.017   1   43.926  ? 90   ILE A HG13 1 c 
ATOM   1060  H  HG21 . ILE A 1 84  ? 45.477  -0.047  7.076   1   39.434  ? 90   ILE A HG21 1 c 
ATOM   1061  H  HG22 . ILE A 1 84  ? 45.946  1.431   7.411   1   39.41   ? 90   ILE A HG22 1 c 
ATOM   1062  H  HG23 . ILE A 1 84  ? 46.864  0.2     7.803   1   39.287  ? 90   ILE A HG23 1 c 
ATOM   1063  H  HD11 . ILE A 1 84  ? 45.498  -0.34   3.626   1   49.36   ? 90   ILE A HD11 1 c 
ATOM   1064  H  HD12 . ILE A 1 84  ? 44.394  0.807   3.605   1   49.399  ? 90   ILE A HD12 1 c 
ATOM   1065  H  HD13 . ILE A 1 84  ? 44.545  -0.129  4.886   1   49.49   ? 90   ILE A HD13 1 c 
ATOM   1066  N  N    . ARG A 1 85  ? 49.882  1.668   7.628   1   30.732  ? 91   ARG A N    1 ? 
ATOM   1067  C  CA   . ARG A 1 85  ? 51.101  1.299   8.339   1   32.445  ? 91   ARG A CA   1 ? 
ATOM   1068  C  C    . ARG A 1 85  ? 50.818  0.236   9.393   1   32.207  ? 91   ARG A C    1 ? 
ATOM   1069  O  O    . ARG A 1 85  ? 49.735  0.223   9.969   1   35.176  ? 91   ARG A O    1 ? 
ATOM   1070  C  CB   . ARG A 1 85  ? 51.732  2.532   8.989   1   30.789  ? 91   ARG A CB   1 ? 
ATOM   1071  C  CG   . ARG A 1 85  ? 52.138  3.605   7.982   1   32.324  ? 91   ARG A CG   1 ? 
ATOM   1072  C  CD   . ARG A 1 85  ? 52.623  4.924   8.549   1   34.528  ? 91   ARG A CD   1 ? 
ATOM   1073  N  NE   . ARG A 1 85  ? 51.562  5.524   9.357   1   42.322  ? 91   ARG A NE   1 ? 
ATOM   1074  C  CZ   . ARG A 1 85  ? 51.052  6.727   9.266   1   46.43   ? 91   ARG A CZ   1 ? 
ATOM   1075  N  NH1  . ARG A 1 85  ? 51.683  7.633   8.568   1   53.27   ? 91   ARG A NH1  1 ? 
ATOM   1076  N  NH2  . ARG A 1 85  ? 49.921  7.021   9.889   1   38.59   ? 91   ARG A NH2  1 ? 
ATOM   1077  H  H    . ARG A 1 85  ? 49.492  2.476   7.801   1   31.708  ? 91   ARG A H    1 c 
ATOM   1078  H  HA   . ARG A 1 85  ? 51.74   0.931   7.681   1   31.764  ? 91   ARG A HA   1 c 
ATOM   1079  H  HB2  . ARG A 1 85  ? 51.092  2.915   9.625   1   31.655  ? 91   ARG A HB2  1 c 
ATOM   1080  H  HB3  . ARG A 1 85  ? 52.525  2.255   9.493   1   31.538  ? 91   ARG A HB3  1 c 
ATOM   1081  H  HG2  . ARG A 1 85  ? 52.845  3.238   7.409   1   32.454  ? 91   ARG A HG2  1 c 
ATOM   1082  H  HG3  . ARG A 1 85  ? 51.372  3.787   7.396   1   32.443  ? 91   ARG A HG3  1 c 
ATOM   1083  H  HD2  . ARG A 1 85  ? 53.415  4.777   9.106   1   35.744  ? 91   ARG A HD2  1 c 
ATOM   1084  H  HD3  . ARG A 1 85  ? 52.865  5.53    7.819   1   35.915  ? 91   ARG A HD3  1 c 
ATOM   1085  H  HE   . ARG A 1 85  ? 51.231  5.029   9.991   1   41.047  ? 91   ARG A HE   1 c 
ATOM   1086  H  HH11 . ARG A 1 85  ? 52.555  7.741   8.669   1   50.797  ? 91   ARG A HH11 1 c 
ATOM   1087  H  HH12 . ARG A 1 85  ? 51.232  8.139   7.998   1   51      ? 91   ARG A HH12 1 c 
ATOM   1088  H  HH21 . ARG A 1 85  ? 49.458  6.385   10.292  1   40.885  ? 91   ARG A HH21 1 c 
ATOM   1089  H  HH22 . ARG A 1 85  ? 49.632  7.857   9.899   1   40.939  ? 91   ARG A HH22 1 c 
ATOM   1090  N  N    . ALA A 1 86  ? 51.832  -0.575  9.718   1   28.98   ? 92   ALA A N    1 ? 
ATOM   1091  C  CA   . ALA A 1 86  ? 51.762  -1.503  10.836  1   32.24   ? 92   ALA A CA   1 ? 
ATOM   1092  C  C    . ALA A 1 86  ? 51.294  -0.808  12.105  1   32.511  ? 92   ALA A C    1 ? 
ATOM   1093  O  O    . ALA A 1 86  ? 50.41   -1.344  12.76   1   41.771  ? 92   ALA A O    1 ? 
ATOM   1094  C  CB   . ALA A 1 86  ? 53.075  -2.225  11.096  1   35.238  ? 92   ALA A CB   1 ? 
ATOM   1095  H  H    . ALA A 1 86  ? 52.599  -0.547  9.222   1   30.495  ? 92   ALA A H    1 c 
ATOM   1096  H  HA   . ALA A 1 86  ? 51.075  -2.188  10.605  1   32.199  ? 92   ALA A HA   1 c 
ATOM   1097  H  HB1  . ALA A 1 86  ? 53.403  -2.613  10.269  1   34.325  ? 92   ALA A HB1  1 c 
ATOM   1098  H  HB2  . ALA A 1 86  ? 53.732  -1.597  11.44   1   34.326  ? 92   ALA A HB2  1 c 
ATOM   1099  H  HB3  . ALA A 1 86  ? 52.935  -2.931  11.749  1   34.326  ? 92   ALA A HB3  1 c 
ATOM   1100  N  N    . THR A 1 87  ? 51.873  0.351   12.448  1   31.115  ? 93   THR A N    1 ? 
ATOM   1101  C  CA   . THR A 1 87  ? 51.468  1.136   13.607  1   33.607  ? 93   THR A CA   1 ? 
ATOM   1102  C  C    . THR A 1 87  ? 50.034  1.66    13.475  1   34.307  ? 93   THR A C    1 ? 
ATOM   1103  O  O    . THR A 1 87  ? 49.42   2.001   14.485  1   37.422  ? 93   THR A O    1 ? 
ATOM   1104  C  CB   . THR A 1 87  ? 52.425  2.314   13.879  1   35.821  ? 93   THR A CB   1 ? 
ATOM   1105  O  OG1  . THR A 1 87  ? 52.483  3.162   12.749  1   29.362  ? 93   THR A OG1  1 ? 
ATOM   1106  C  CG2  . THR A 1 87  ? 53.858  1.894   14.165  1   39.898  ? 93   THR A CG2  1 ? 
ATOM   1107  H  H    . THR A 1 87  ? 52.556  0.667   11.928  1   32.083  ? 93   THR A H    1 c 
ATOM   1108  H  HA   . THR A 1 87  ? 51.5    0.544   14.387  1   33.696  ? 93   THR A HA   1 c 
ATOM   1109  H  HB   . THR A 1 87  ? 52.09   2.829   14.651  1   34.741  ? 93   THR A HB   1 c 
ATOM   1110  H  HG1  . THR A 1 87  ? 52.759  2.728   12.077  0   29.57   ? 93   THR A HG1  1 c 
ATOM   1111  H  HG21 . THR A 1 87  ? 54.418  2.685   14.243  1   38.625  ? 93   THR A HG21 1 c 
ATOM   1112  H  HG22 . THR A 1 87  ? 54.187  1.337   13.443  1   38.553  ? 93   THR A HG22 1 c 
ATOM   1113  H  HG23 . THR A 1 87  ? 53.889  1.393   14.998  1   38.625  ? 93   THR A HG23 1 c 
ATOM   1114  N  N    . ASP A 1 88  ? 49.509  1.804   12.255  1   34.188  ? 94   ASP A N    1 ? 
ATOM   1115  C  CA   . ASP A 1 88  ? 48.111  2.197   12.088  1   34.497  ? 94   ASP A CA   1 ? 
ATOM   1116  C  C    . ASP A 1 88  ? 47.166  1.121   12.634  1   33.131  ? 94   ASP A C    1 ? 
ATOM   1117  O  O    . ASP A 1 88  ? 46.161  1.485   13.211  1   36.603  ? 94   ASP A O    1 ? 
ATOM   1118  C  CB   . ASP A 1 88  ? 47.678  2.472   10.665  1   32.923  ? 94   ASP A CB   1 ? 
ATOM   1119  C  CG   . ASP A 1 88  ? 48.323  3.684   10.019  1   40.377  ? 94   ASP A CG   1 ? 
ATOM   1120  O  OD1  . ASP A 1 88  ? 48.78   4.57    10.778  1   38.735  ? 94   ASP A OD1  1 ? 
ATOM   1121  O  OD2  . ASP A 1 88  ? 48.396  3.705   8.76    1   37.559  ? 94   ASP A OD2  1 ? 
ATOM   1122  H  H    . ASP A 1 88  ? 50.028  1.678   11.513  1   34.235  ? 94   ASP A H    1 c 
ATOM   1123  H  HA   . ASP A 1 88  ? 47.964  3.023   12.603  1   33.946  ? 94   ASP A HA   1 c 
ATOM   1124  H  HB2  . ASP A 1 88  ? 47.866  1.688   10.111  1   34.877  ? 94   ASP A HB2  1 c 
ATOM   1125  H  HB3  . ASP A 1 88  ? 46.708  2.615   10.657  1   34.874  ? 94   ASP A HB3  1 c 
ATOM   1126  N  N    . TYR A 1 89  ? 47.544  -0.156  12.521  1   30.97   ? 95   TYR A N    1 ? 
ATOM   1127  C  CA   . TYR A 1 89  ? 46.834  -1.271  13.136  1   31.673  ? 95   TYR A CA   1 ? 
ATOM   1128  C  C    . TYR A 1 89  ? 47.151  -1.396  14.635  1   43.033  ? 95   TYR A C    1 ? 
ATOM   1129  O  O    . TYR A 1 89  ? 46.235  -1.612  15.459  1   39.899  ? 95   TYR A O    1 ? 
ATOM   1130  C  CB   . TYR A 1 89  ? 47.207  -2.573  12.419  1   33.825  ? 95   TYR A CB   1 ? 
ATOM   1131  C  CG   . TYR A 1 89  ? 46.7    -2.668  10.993  1   33.912  ? 95   TYR A CG   1 ? 
ATOM   1132  C  CD1  . TYR A 1 89  ? 45.41   -3.129  10.699  1   34.263  ? 95   TYR A CD1  1 ? 
ATOM   1133  C  CD2  . TYR A 1 89  ? 47.504  -2.265  9.939   1   33.097  ? 95   TYR A CD2  1 ? 
ATOM   1134  C  CE1  . TYR A 1 89  ? 44.959  -3.211  9.388   1   36.479  ? 95   TYR A CE1  1 ? 
ATOM   1135  C  CE2  . TYR A 1 89  ? 47.067  -2.358  8.629   1   31.475  ? 95   TYR A CE2  1 ? 
ATOM   1136  C  CZ   . TYR A 1 89  ? 45.796  -2.839  8.345   1   36.214  ? 95   TYR A CZ   1 ? 
ATOM   1137  O  OH   . TYR A 1 89  ? 45.386  -2.81   7.031   1   32.86   ? 95   TYR A OH   1 ? 
ATOM   1138  H  H    . TYR A 1 89  ? 48.287  -0.344  12.023  1   31.694  ? 95   TYR A H    1 c 
ATOM   1139  H  HA   . TYR A 1 89  ? 45.858  -1.12   13.03   1   33.765  ? 95   TYR A HA   1 c 
ATOM   1140  H  HB2  . TYR A 1 89  ? 48.186  -2.658  12.414  1   33.429  ? 95   TYR A HB2  1 c 
ATOM   1141  H  HB3  . TYR A 1 89  ? 46.845  -3.326  12.934  1   33.483  ? 95   TYR A HB3  1 c 
ATOM   1142  H  HD1  . TYR A 1 89  ? 44.843  -3.403  11.402  1   34.665  ? 95   TYR A HD1  1 c 
ATOM   1143  H  HD2  . TYR A 1 89  ? 48.379  -1.959  10.115  1   32.956  ? 95   TYR A HD2  1 c 
ATOM   1144  H  HE1  . TYR A 1 89  ? 44.087  -3.517  9.206   1   35.81   ? 95   TYR A HE1  1 c 
ATOM   1145  H  HE2  . TYR A 1 89  ? 47.626  -2.072  7.927   1   32.976  ? 95   TYR A HE2  1 c 
ATOM   1146  H  HH   . TYR A 1 89  ? 45.059  -2.023  6.845   0   32.69   ? 95   TYR A HH   1 c 
ATOM   1147  N  N    . LEU A 1 90  ? 48.442  -1.25   14.995  1   35.425  ? 96   LEU A N    1 ? 
ATOM   1148  C  CA   . LEU A 1 90  ? 48.838  -1.423  16.384  1   35.093  ? 96   LEU A CA   1 ? 
ATOM   1149  C  C    . LEU A 1 90  ? 48.152  -0.402  17.303  1   33.704  ? 96   LEU A C    1 ? 
ATOM   1150  O  O    . LEU A 1 90  ? 47.934  -0.68   18.481  1   39.297  ? 96   LEU A O    1 ? 
ATOM   1151  C  CB   . LEU A 1 90  ? 50.355  -1.393  16.536  1   37.232  ? 96   LEU A CB   1 ? 
ATOM   1152  C  CG   . LEU A 1 90  ? 51.091  -2.606  15.953  1   37.262  ? 96   LEU A CG   1 ? 
ATOM   1153  C  CD1  . LEU A 1 90  ? 52.48   -2.176  15.571  1   35.766  ? 96   LEU A CD1  1 ? 
ATOM   1154  C  CD2  . LEU A 1 90  ? 51.127  -3.777  16.921  1   35.725  ? 96   LEU A CD2  1 ? 
ATOM   1155  H  H    . LEU A 1 90  ? 49.076  -1.046  14.37   1   36.955  ? 96   LEU A H    1 c 
ATOM   1156  H  HA   . LEU A 1 90  ? 48.522  -2.32   16.664  1   35.336  ? 96   LEU A HA   1 c 
ATOM   1157  H  HB2  . LEU A 1 90  ? 50.692  -0.579  16.098  1   36.7    ? 96   LEU A HB2  1 c 
ATOM   1158  H  HB3  . LEU A 1 90  ? 50.568  -1.331  17.496  1   36.709  ? 96   LEU A HB3  1 c 
ATOM   1159  H  HG   . LEU A 1 90  ? 50.616  -2.894  15.131  1   36.677  ? 96   LEU A HG   1 c 
ATOM   1160  H  HD11 . LEU A 1 90  ? 52.433  -1.526  14.849  1   36.191  ? 96   LEU A HD11 1 c 
ATOM   1161  H  HD12 . LEU A 1 90  ? 52.99   -2.949  15.276  1   36.202  ? 96   LEU A HD12 1 c 
ATOM   1162  H  HD13 . LEU A 1 90  ? 52.919  -1.774  16.339  1   36.202  ? 96   LEU A HD13 1 c 
ATOM   1163  H  HD21 . LEU A 1 90  ? 50.22   -4.051  17.135  1   36.172  ? 96   LEU A HD21 1 c 
ATOM   1164  H  HD22 . LEU A 1 90  ? 51.585  -3.512  17.736  1   36.172  ? 96   LEU A HD22 1 c 
ATOM   1165  H  HD23 . LEU A 1 90  ? 51.601  -4.521  16.512  1   36.172  ? 96   LEU A HD23 1 c 
ATOM   1166  N  N    . GLU A 1 91  ? 47.811  0.764   16.773  1   36.191  ? 97   GLU A N    1 ? 
ATOM   1167  C  CA   . GLU A 1 91  ? 47.172  1.82    17.533  1   41.616  ? 97   GLU A CA   1 ? 
ATOM   1168  C  C    . GLU A 1 91  ? 45.874  1.337   18.188  1   45.084  ? 97   GLU A C    1 ? 
ATOM   1169  O  O    . GLU A 1 91  ? 45.546  1.812   19.279  1   39.353  ? 97   GLU A O    1 ? 
ATOM   1170  C  CB   . GLU A 1 91  ? 46.92   3.058   16.674  1   37.177  ? 97   GLU A CB   1 ? 
ATOM   1171  C  CG   . GLU A 1 91  ? 46.7    4.351   17.47   1   48.757  ? 97   GLU A CG   1 ? 
ATOM   1172  C  CD   . GLU A 1 91  ? 47.754  4.72    18.53   1   55.182  ? 97   GLU A CD   1 ? 
ATOM   1173  O  OE1  . GLU A 1 91  ? 47.416  5.318   19.587  1   56.503  ? 97   GLU A OE1  1 ? 
ATOM   1174  O  OE2  . GLU A 1 91  ? 48.936  4.371   18.328  1   48.794  ? 97   GLU A OE2  1 ? 
ATOM   1175  H  H    . GLU A 1 91  ? 47.997  0.919   15.892  1   36.777  ? 97   GLU A H    1 c 
ATOM   1176  H  HA   . GLU A 1 91  ? 47.794  2.078   18.258  1   40.363  ? 97   GLU A HA   1 c 
ATOM   1177  H  HB2  . GLU A 1 91  ? 47.687  3.189   16.079  1   40.537  ? 97   GLU A HB2  1 c 
ATOM   1178  H  HB3  . GLU A 1 91  ? 46.133  2.896   16.112  1   40.585  ? 97   GLU A HB3  1 c 
ATOM   1179  H  HG2  . GLU A 1 91  ? 46.639  5.097   16.835  1   47.135  ? 97   GLU A HG2  1 c 
ATOM   1180  H  HG3  . GLU A 1 91  ? 45.83   4.293   17.919  1   47.135  ? 97   GLU A HG3  1 c 
ATOM   1181  N  N    . TYR A 1 92  ? 45.146  0.418   17.535  1   42.655  ? 98   TYR A N    1 ? 
ATOM   1182  C  CA   . TYR A 1 92  ? 43.867  -0.018  18.059  1   42.522  ? 98   TYR A CA   1 ? 
ATOM   1183  C  C    . TYR A 1 92  ? 44.103  -0.66   19.421  1   43.871  ? 98   TYR A C    1 ? 
ATOM   1184  O  O    . TYR A 1 92  ? 43.375  -0.389  20.364  1   45.685  ? 98   TYR A O    1 ? 
ATOM   1185  C  CB   . TYR A 1 92  ? 43.06   -0.966  17.174  1   45.376  ? 98   TYR A CB   1 ? 
ATOM   1186  C  CG   . TYR A 1 92  ? 41.787  -1.384  17.894  1   39.365  ? 98   TYR A CG   1 ? 
ATOM   1187  C  CD1  . TYR A 1 92  ? 40.797  -0.445  18.15   1   49.479  ? 98   TYR A CD1  1 ? 
ATOM   1188  C  CD2  . TYR A 1 92  ? 41.587  -2.668  18.349  1   41.728  ? 98   TYR A CD2  1 ? 
ATOM   1189  C  CE1  . TYR A 1 92  ? 39.626  -0.777  18.803  1   45.251  ? 98   TYR A CE1  1 ? 
ATOM   1190  C  CE2  . TYR A 1 92  ? 40.416  -3.025  19.006  1   39.53   ? 98   TYR A CE2  1 ? 
ATOM   1191  C  CZ   . TYR A 1 92  ? 39.444  -2.07   19.241  1   39.787  ? 98   TYR A CZ   1 ? 
ATOM   1192  O  OH   . TYR A 1 92  ? 38.302  -2.353  19.896  1   43.727  ? 98   TYR A OH   1 ? 
ATOM   1193  H  H    . TYR A 1 92  ? 45.445  0.07    16.744  1   43.068  ? 98   TYR A H    1 c 
ATOM   1194  H  HA   . TYR A 1 92  ? 43.315  0.795   18.202  1   43.361  ? 98   TYR A HA   1 c 
ATOM   1195  H  HB2  . TYR A 1 92  ? 42.829  -0.508  16.335  1   43.291  ? 98   TYR A HB2  1 c 
ATOM   1196  H  HB3  . TYR A 1 92  ? 43.601  -1.762  16.972  1   43.277  ? 98   TYR A HB3  1 c 
ATOM   1197  H  HD1  . TYR A 1 92  ? 40.918  0.442   17.851  1   45.838  ? 98   TYR A HD1  1 c 
ATOM   1198  H  HD2  . TYR A 1 92  ? 42.247  -3.325  18.191  1   40.761  ? 98   TYR A HD2  1 c 
ATOM   1199  H  HE1  . TYR A 1 92  ? 38.967  -0.125  18.964  1   44.778  ? 98   TYR A HE1  1 c 
ATOM   1200  H  HE2  . TYR A 1 92  ? 40.293  -3.908  19.311  1   40.19   ? 98   TYR A HE2  1 c 
ATOM   1201  H  HH   . TYR A 1 92  ? 37.701  -2.607  19.358  0   43.65   ? 98   TYR A HH   1 c 
ATOM   1202  N  N    . GLU A 1 93  ? 45.148  -1.486  19.5    1   45.687  ? 99   GLU A N    1 ? 
ATOM   1203  C  CA   . GLU A 1 93  ? 45.591  -2.154  20.709  1   42.807  ? 99   GLU A CA   1 ? 
ATOM   1204  C  C    . GLU A 1 93  ? 46.129  -1.188  21.759  1   42.584  ? 99   GLU A C    1 ? 
ATOM   1205  O  O    . GLU A 1 93  ? 46.063  -1.467  22.951  1   44.036  ? 99   GLU A O    1 ? 
ATOM   1206  C  CB   . GLU A 1 93  ? 46.777  -3.068  20.398  1   41.884  ? 99   GLU A CB   1 ? 
ATOM   1207  C  CG   . GLU A 1 93  ? 46.378  -4.505  20.111  1   38.08   ? 99   GLU A CG   1 ? 
ATOM   1208  C  CD   . GLU A 1 93  ? 47.572  -5.359  19.747  1   36.715  ? 99   GLU A CD   1 ? 
ATOM   1209  O  OE1  . GLU A 1 93  ? 47.29   -6.524  19.521  1   45.08   ? 99   GLU A OE1  1 ? 
ATOM   1210  O  OE2  . GLU A 1 93  ? 48.754  -4.929  19.717  1   40.413  ? 99   GLU A OE2  1 ? 
ATOM   1211  H  H    . GLU A 1 93  ? 45.613  -1.652  18.731  1   44.502  ? 99   GLU A H    1 c 
ATOM   1212  H  HA   . GLU A 1 93  ? 44.838  -2.675  21.089  1   43.116  ? 99   GLU A HA   1 c 
ATOM   1213  H  HB2  . GLU A 1 93  ? 47.262  -2.714  19.626  1   41.218  ? 99   GLU A HB2  1 c 
ATOM   1214  H  HB3  . GLU A 1 93  ? 47.391  -3.065  21.162  1   41.195  ? 99   GLU A HB3  1 c 
ATOM   1215  H  HG2  . GLU A 1 93  ? 45.947  -4.885  20.906  1   38.596  ? 99   GLU A HG2  1 c 
ATOM   1216  H  HG3  . GLU A 1 93  ? 45.732  -4.526  19.375  1   38.584  ? 99   GLU A HG3  1 c 
ATOM   1217  N  N    . ARG A 1 94  ? 46.754  -0.108  21.312  1   40.803  ? 100  ARG A N    1 ? 
ATOM   1218  C  CA   . ARG A 1 94  ? 47.478  0.75    22.222  1   46.304  ? 100  ARG A CA   1 ? 
ATOM   1219  C  C    . ARG A 1 94  ? 46.477  1.652   22.933  1   50.134  ? 100  ARG A C    1 ? 
ATOM   1220  O  O    . ARG A 1 94  ? 46.624  1.888   24.124  1   51.029  ? 100  ARG A O    1 ? 
ATOM   1221  C  CB   . ARG A 1 94  ? 48.594  1.491   21.476  1   43.322  ? 100  ARG A CB   1 ? 
ATOM   1222  C  CG   . ARG A 1 94  ? 49.73   0.581   21.022  1   48.707  ? 100  ARG A CG   1 ? 
ATOM   1223  C  CD   . ARG A 1 94  ? 50.759  1.276   20.112  1   47.281  ? 100  ARG A CD   1 ? 
ATOM   1224  N  NE   . ARG A 1 94  ? 51.853  0.368   19.749  1   51.663  ? 100  ARG A NE   1 ? 
ATOM   1225  C  CZ   . ARG A 1 94  ? 52.954  0.763   19.107  1   52.605  ? 100  ARG A CZ   1 ? 
ATOM   1226  N  NH1  . ARG A 1 94  ? 53.063  2.022   18.742  1   51.007  ? 100  ARG A NH1  1 ? 
ATOM   1227  N  NH2  . ARG A 1 94  ? 53.926  -0.091  18.819  1   47.577  ? 100  ARG A NH2  1 ? 
ATOM   1228  H  H    . ARG A 1 94  ? 46.741  0.096   20.422  1   42.508  ? 100  ARG A H    1 c 
ATOM   1229  H  HA   . ARG A 1 94  ? 47.912  0.177   22.905  1   45.294  ? 100  ARG A HA   1 c 
ATOM   1230  H  HB2  . ARG A 1 94  ? 48.21   1.935   20.69   1   45.153  ? 100  ARG A HB2  1 c 
ATOM   1231  H  HB3  . ARG A 1 94  ? 48.961  2.186   22.064  1   45.168  ? 100  ARG A HB3  1 c 
ATOM   1232  H  HG2  . ARG A 1 94  ? 50.194  0.233   21.814  1   47.089  ? 100  ARG A HG2  1 c 
ATOM   1233  H  HG3  . ARG A 1 94  ? 49.352  -0.188  20.543  1   47.024  ? 100  ARG A HG3  1 c 
ATOM   1234  H  HD2  . ARG A 1 94  ? 50.315  1.59    19.298  1   48.608  ? 100  ARG A HD2  1 c 
ATOM   1235  H  HD3  . ARG A 1 94  ? 51.126  2.054   20.578  1   48.623  ? 100  ARG A HD3  1 c 
ATOM   1236  H  HE   . ARG A 1 94  ? 51.781  -0.473  19.964  1   50.786  ? 100  ARG A HE   1 c 
ATOM   1237  H  HH11 . ARG A 1 94  ? 52.433  2.393   18.239  1   51.466  ? 100  ARG A HH11 1 c 
ATOM   1238  H  HH12 . ARG A 1 94  ? 53.772  2.491   18.997  1   51.487  ? 100  ARG A HH12 1 c 
ATOM   1239  H  HH21 . ARG A 1 94  ? 53.855  -0.939  19.06   1   49.108  ? 100  ARG A HH21 1 c 
ATOM   1240  H  HH22 . ARG A 1 94  ? 54.643  0.19    18.386  1   49.094  ? 100  ARG A HH22 1 c 
ATOM   1241  N  N    . SER A 1 95  ? 45.448  2.096   22.204  1   43.788  ? 101  SER A N    1 ? 
ATOM   1242  C  CA   . SER A 1 95  ? 44.67   3.253   22.609  1   43.439  ? 101  SER A CA   1 ? 
ATOM   1243  C  C    . SER A 1 95  ? 43.196  3.16    22.18   1   40.961  ? 101  SER A C    1 ? 
ATOM   1244  O  O    . SER A 1 95  ? 42.423  4.09    22.418  1   42.226  ? 101  SER A O    1 ? 
ATOM   1245  C  CB   . SER A 1 95  ? 45.293  4.483   22.006  1   41.571  ? 101  SER A CB   1 ? 
ATOM   1246  O  OG   . SER A 1 95  ? 44.937  4.568   20.622  1   45.194  ? 101  SER A OG   1 ? 
ATOM   1247  H  H    . SER A 1 95  ? 45.254  1.689   21.41   1   44.936  ? 101  SER A H    1 c 
ATOM   1248  H  HA   . SER A 1 95  ? 44.705  3.33    23.597  1   42.78   ? 101  SER A HA   1 c 
ATOM   1249  H  HB2  . SER A 1 95  ? 44.973  5.276   22.477  1   42.837  ? 101  SER A HB2  1 c 
ATOM   1250  H  HB3  . SER A 1 95  ? 46.263  4.437   22.095  1   42.865  ? 101  SER A HB3  1 c 
ATOM   1251  H  HG   . SER A 1 95  ? 45.3    5.246   20.245  0   43.95   ? 101  SER A HG   1 c 
ATOM   1252  N  N    . GLY A 1 96  ? 42.83   2.098   21.457  1   37.109  ? 102  GLY A N    1 ? 
ATOM   1253  C  CA   . GLY A 1 96  ? 41.528  1.978   20.819  1   39.235  ? 102  GLY A CA   1 ? 
ATOM   1254  C  C    . GLY A 1 96  ? 41.245  2.959   19.673  1   46.638  ? 102  GLY A C    1 ? 
ATOM   1255  O  O    . GLY A 1 96  ? 40.107  2.997   19.174  1   44.077  ? 102  GLY A O    1 ? 
ATOM   1256  H  H    . GLY A 1 96  ? 43.412  1.4     21.371  1   38.634  ? 102  GLY A H    1 c 
ATOM   1257  H  HA2  . GLY A 1 96  ? 41.436  1.06    20.476  1   40.312  ? 102  GLY A HA2  1 c 
ATOM   1258  H  HA3  . GLY A 1 96  ? 40.836  2.098   21.511  1   40.264  ? 102  GLY A HA3  1 c 
ATOM   1259  N  N    . GLU A 1 97  ? 42.236  3.743   19.218  1   40.683  ? 103  GLU A N    1 ? 
ATOM   1260  C  CA   . GLU A 1 97  ? 41.974  4.675   18.124  1   47.074  ? 103  GLU A CA   1 ? 
ATOM   1261  C  C    . GLU A 1 97  ? 41.86   3.873   16.822  1   46.574  ? 103  GLU A C    1 ? 
ATOM   1262  O  O    . GLU A 1 97  ? 42.56   2.881   16.632  1   49.06   ? 103  GLU A O    1 ? 
ATOM   1263  C  CB   . GLU A 1 97  ? 42.981  5.827   18.206  1   50.501  ? 103  GLU A CB   1 ? 
ATOM   1264  C  CG   . GLU A 1 97  ? 43.315  6.51    16.885  1   59.516  ? 103  GLU A CG   1 ? 
ATOM   1265  C  CD   . GLU A 1 97  ? 42.217  7.226   16.123  1   62.816  ? 103  GLU A CD   1 ? 
ATOM   1266  O  OE1  . GLU A 1 97  ? 41.014  7.241   16.485  1   74.392  ? 103  GLU A OE1  1 ? 
ATOM   1267  O  OE2  . GLU A 1 97  ? 42.636  7.755   15.078  1   50.449  ? 103  GLU A OE2  1 ? 
ATOM   1268  H  H    . GLU A 1 97  ? 43.076  3.689   19.574  1   43.471  ? 103  GLU A H    1 c 
ATOM   1269  H  HA   . GLU A 1 97  ? 41.087  5.085   18.293  1   46.233  ? 103  GLU A HA   1 c 
ATOM   1270  H  HB2  . GLU A 1 97  ? 42.634  6.503   18.825  1   51.579  ? 103  GLU A HB2  1 c 
ATOM   1271  H  HB3  . GLU A 1 97  ? 43.819  5.486   18.58   1   51.447  ? 103  GLU A HB3  1 c 
ATOM   1272  H  HG2  . GLU A 1 97  ? 44.027  7.163   17.056  1   58.026  ? 103  GLU A HG2  1 c 
ATOM   1273  H  HG3  . GLU A 1 97  ? 43.702  5.838   16.284  1   57.978  ? 103  GLU A HG3  1 c 
ATOM   1274  N  N    . ARG A 1 98  ? 40.904  4.246   15.966  1   42.859  ? 104  ARG A N    1 ? 
ATOM   1275  C  CA   . ARG A 1 98  ? 40.653  3.467   14.772  1   47.321  ? 104  ARG A CA   1 ? 
ATOM   1276  C  C    . ARG A 1 98  ? 40.698  4.3     13.497  1   41.091  ? 104  ARG A C    1 ? 
ATOM   1277  O  O    . ARG A 1 98  ? 40.971  3.735   12.444  1   36.459  ? 104  ARG A O    1 ? 
ATOM   1278  C  CB   . ARG A 1 98  ? 39.377  2.643   14.953  1   52.613  ? 104  ARG A CB   1 ? 
ATOM   1279  C  CG   . ARG A 1 98  ? 38.045  3.322   15.209  1   58.315  ? 104  ARG A CG   1 ? 
ATOM   1280  C  CD   . ARG A 1 98  ? 37.098  2.35    15.947  1   55.396  ? 104  ARG A CD   1 ? 
ATOM   1281  N  NE   . ARG A 1 98  ? 36.814  1.226   15.061  1   59.977  ? 104  ARG A NE   1 ? 
ATOM   1282  C  CZ   . ARG A 1 98  ? 35.718  0.495   15.003  1   60.782  ? 104  ARG A CZ   1 ? 
ATOM   1283  N  NH1  . ARG A 1 98  ? 34.959  0.337   16.064  1   59.17   ? 104  ARG A NH1  1 ? 
ATOM   1284  N  NH2  . ARG A 1 98  ? 35.463  -0.19   13.908  1   58.166  ? 104  ARG A NH2  1 ? 
ATOM   1285  H  H    . ARG A 1 98  ? 40.388  4.979   16.144  1   44.821  ? 104  ARG A H    1 c 
ATOM   1286  H  HA   . ARG A 1 98  ? 41.383  2.803   14.696  1   46.152  ? 104  ARG A HA   1 c 
ATOM   1287  H  HB2  . ARG A 1 98  ? 39.278  2.094   14.146  1   52.635  ? 104  ARG A HB2  1 c 
ATOM   1288  H  HB3  . ARG A 1 98  ? 39.541  2.023   15.696  1   52.635  ? 104  ARG A HB3  1 c 
ATOM   1289  H  HG2  . ARG A 1 98  ? 38.182  4.125   15.758  1   56.149  ? 104  ARG A HG2  1 c 
ATOM   1290  H  HG3  . ARG A 1 98  ? 37.64   3.587   14.355  1   56.278  ? 104  ARG A HG3  1 c 
ATOM   1291  H  HD2  . ARG A 1 98  ? 37.514  2.025   16.772  1   57.065  ? 104  ARG A HD2  1 c 
ATOM   1292  H  HD3  . ARG A 1 98  ? 36.262  2.806   16.177  1   57.108  ? 104  ARG A HD3  1 c 
ATOM   1293  H  HE   . ARG A 1 98  ? 37.445  0.991   14.508  1   58.945  ? 104  ARG A HE   1 c 
ATOM   1294  H  HH11 . ARG A 1 98  ? 35.312  0.396   16.881  1   59.636  ? 104  ARG A HH11 1 c 
ATOM   1295  H  HH12 . ARG A 1 98  ? 34.093  0.174   15.958  1   59.641  ? 104  ARG A HH12 1 c 
ATOM   1296  H  HH21 . ARG A 1 98  ? 36.124  -0.421  13.368  1   58.968  ? 104  ARG A HH21 1 c 
ATOM   1297  H  HH22 . ARG A 1 98  ? 34.63   -0.421  13.717  1   58.968  ? 104  ARG A HH22 1 c 
ATOM   1298  N  N    . ASN A 1 99  ? 40.399  5.605   13.585  1   40.411  ? 105  ASN A N    1 ? 
ATOM   1299  C  CA   . ASN A 1 99  ? 40.407  6.49    12.431  1   44.139  ? 105  ASN A CA   1 ? 
ATOM   1300  C  C    . ASN A 1 99  ? 41.777  6.593   11.768  1   41.06   ? 105  ASN A C    1 ? 
ATOM   1301  O  O    . ASN A 1 99  ? 41.839  6.876   10.575  1   45.173  ? 105  ASN A O    1 ? 
ATOM   1302  C  CB   . ASN A 1 99  ? 39.952  7.905   12.768  1   47.212  ? 105  ASN A CB   1 ? 
ATOM   1303  C  CG   . ASN A 1 99  ? 38.48   7.942   13.106  1   49.423  ? 105  ASN A CG   1 ? 
ATOM   1304  O  OD1  . ASN A 1 99  ? 37.719  7.009   12.815  1   53.51   ? 105  ASN A OD1  1 ? 
ATOM   1305  N  ND2  . ASN A 1 99  ? 38.057  9.025   13.72   1   53.464  ? 105  ASN A ND2  1 ? 
ATOM   1306  H  H    . ASN A 1 99  ? 40.172  5.955   14.397  1   41.544  ? 105  ASN A H    1 c 
ATOM   1307  H  HA   . ASN A 1 99  ? 39.778  6.128   11.768  1   43.436  ? 105  ASN A HA   1 c 
ATOM   1308  H  HB2  . ASN A 1 99  ? 40.467  8.238   13.53   1   47.029  ? 105  ASN A HB2  1 c 
ATOM   1309  H  HB3  . ASN A 1 99  ? 40.123  8.493   12.005  1   46.961  ? 105  ASN A HB3  1 c 
ATOM   1310  H  HD21 . ASN A 1 99  ? 37.202  9.097   13.949  1   52.177  ? 105  ASN A HD21 1 c 
ATOM   1311  H  HD22 . ASN A 1 99  ? 38.622  9.682   13.906  1   52.107  ? 105  ASN A HD22 1 c 
ATOM   1312  N  N    . ILE A 1 100 ? 42.842  6.402   12.547  1   44.76   ? 106  ILE A N    1 ? 
ATOM   1313  C  CA   . ILE A 1 100 ? 44.21   6.464   12.058  1   43.708  ? 106  ILE A CA   1 ? 
ATOM   1314  C  C    . ILE A 1 100 ? 44.356  5.408   10.977  1   38.688  ? 106  ILE A C    1 ? 
ATOM   1315  O  O    . ILE A 1 100 ? 45.024  5.669   10.005  1   35.704  ? 106  ILE A O    1 ? 
ATOM   1316  C  CB   . ILE A 1 100 ? 45.239  6.264   13.191  1   47.843  ? 106  ILE A CB   1 ? 
ATOM   1317  C  CG1  . ILE A 1 100 ? 46.652  6.606   12.748  1   51.518  ? 106  ILE A CG1  1 ? 
ATOM   1318  C  CG2  . ILE A 1 100 ? 45.179  4.85    13.765  1   50.351  ? 106  ILE A CG2  1 ? 
ATOM   1319  C  CD1  . ILE A 1 100 ? 47.667  6.672   13.881  1   52.33   ? 106  ILE A CD1  1 ? 
ATOM   1320  H  H    . ILE A 1 100 ? 42.711  6.242   13.437  1   43.762  ? 106  ILE A H    1 c 
ATOM   1321  H  HA   . ILE A 1 100 ? 44.355  7.343   11.658  1   43.629  ? 106  ILE A HA   1 c 
ATOM   1322  H  HB   . ILE A 1 100 ? 45.002  6.883   13.91   1   48.169  ? 106  ILE A HB   1 c 
ATOM   1323  H  HG12 . ILE A 1 100 ? 46.948  5.934   12.102  1   50.687  ? 106  ILE A HG12 1 c 
ATOM   1324  H  HG13 . ILE A 1 100 ? 46.635  7.472   12.292  1   50.755  ? 106  ILE A HG13 1 c 
ATOM   1325  H  HG21 . ILE A 1 100 ? 45.666  4.819   14.606  1   49.565  ? 106  ILE A HG21 1 c 
ATOM   1326  H  HG22 . ILE A 1 100 ? 45.581  4.225   13.138  1   49.448  ? 106  ILE A HG22 1 c 
ATOM   1327  H  HG23 . ILE A 1 100 ? 44.254  4.598   13.922  1   49.424  ? 106  ILE A HG23 1 c 
ATOM   1328  H  HD11 . ILE A 1 100 ? 47.347  7.283   14.572  1   52.083  ? 106  ILE A HD11 1 c 
ATOM   1329  H  HD12 . ILE A 1 100 ? 48.521  6.995   13.534  1   52.083  ? 106  ILE A HD12 1 c 
ATOM   1330  H  HD13 . ILE A 1 100 ? 47.791  5.784   14.268  1   52.063  ? 106  ILE A HD13 1 c 
ATOM   1331  N  N    . MET A 1 101 ? 43.677  4.255   11.136  1   39.294  ? 107  MET A N    1 ? 
ATOM   1332  C  CA   . MET A 1 101 ? 43.706  3.172   10.161  1   37.518  ? 107  MET A CA   1 ? 
ATOM   1333  C  C    . MET A 1 101 ? 42.575  3.297   9.135   1   37.028  ? 107  MET A C    1 ? 
ATOM   1334  O  O    . MET A 1 101 ? 42.805  3.087   7.949   1   37.9    ? 107  MET A O    1 ? 
ATOM   1335  C  CB   . MET A 1 101 ? 43.678  1.841   10.901  1   33.438  ? 107  MET A CB   1 ? 
ATOM   1336  C  CG   . MET A 1 101 ? 43.442  0.619   10.043  1   39.381  ? 107  MET A CG   1 ? 
ATOM   1337  S  SD   . MET A 1 101 ? 41.756  0.324   9.458   1   40.028  ? 107  MET A SD   1 ? 
ATOM   1338  C  CE   . MET A 1 101 ? 41.929  -1.007  8.271   1   34.103  ? 107  MET A CE   1 ? 
ATOM   1339  H  H    . MET A 1 101 ? 43.178  4.14    11.893  1   38.872  ? 107  MET A H    1 c 
ATOM   1340  H  HA   . MET A 1 101 ? 44.562  3.237   9.666   1   36.984  ? 107  MET A HA   1 c 
ATOM   1341  H  HB2  . MET A 1 101 ? 44.533  1.733   11.367  1   35.657  ? 107  MET A HB2  1 c 
ATOM   1342  H  HB3  . MET A 1 101 ? 42.975  1.883   11.583  1   35.669  ? 107  MET A HB3  1 c 
ATOM   1343  H  HG2  . MET A 1 101 ? 44.023  0.679   9.258   1   37.95   ? 107  MET A HG2  1 c 
ATOM   1344  H  HG3  . MET A 1 101 ? 43.725  -0.169  10.547  1   37.887  ? 107  MET A HG3  1 c 
ATOM   1345  H  HE1  . MET A 1 101 ? 41.061  -1.202  7.873   1   35.481  ? 107  MET A HE1  1 c 
ATOM   1346  H  HE2  . MET A 1 101 ? 42.554  -0.739  7.572   1   35.496  ? 107  MET A HE2  1 c 
ATOM   1347  H  HE3  . MET A 1 101 ? 42.267  -1.802  8.722   1   35.496  ? 107  MET A HE3  1 c 
ATOM   1348  N  N    . GLN A 1 102 ? 41.367  3.696   9.571   1   36.54   ? 108  GLN A N    1 ? 
ATOM   1349  C  CA   . GLN A 1 102 ? 40.174  3.669   8.732   1   36.7    ? 108  GLN A CA   1 ? 
ATOM   1350  C  C    . GLN A 1 102 ? 40.241  4.716   7.627   1   39      ? 108  GLN A C    1 ? 
ATOM   1351  O  O    . GLN A 1 102 ? 39.748  4.489   6.525   1   38.414  ? 108  GLN A O    1 ? 
ATOM   1352  C  CB   . GLN A 1 102 ? 38.902  3.71    9.585   1   36.797  ? 108  GLN A CB   1 ? 
ATOM   1353  C  CG   . GLN A 1 102 ? 38.717  2.378   10.32   1   43.892  ? 108  GLN A CG   1 ? 
ATOM   1354  C  CD   . GLN A 1 102 ? 37.541  2.246   11.269  1   40.91   ? 108  GLN A CD   1 ? 
ATOM   1355  O  OE1  . GLN A 1 102 ? 37.388  1.208   11.923  1   40.909  ? 108  GLN A OE1  1 ? 
ATOM   1356  N  NE2  . GLN A 1 102 ? 36.715  3.272   11.372  1   36.86   ? 108  GLN A NE2  1 ? 
ATOM   1357  H  H    . GLN A 1 102 ? 41.286  3.996   10.431  1   36.742  ? 108  GLN A H    1 c 
ATOM   1358  H  HA   . GLN A 1 102 ? 40.161  2.786   8.282   1   37.167  ? 108  GLN A HA   1 c 
ATOM   1359  H  HB2  . GLN A 1 102 ? 38.966  4.44    10.236  1   38.26   ? 108  GLN A HB2  1 c 
ATOM   1360  H  HB3  . GLN A 1 102 ? 38.127  3.878   9.009   1   38.268  ? 108  GLN A HB3  1 c 
ATOM   1361  H  HG2  . GLN A 1 102 ? 38.633  1.665   9.651   1   41.45   ? 108  GLN A HG2  1 c 
ATOM   1362  H  HG3  . GLN A 1 102 ? 39.531  2.192   10.834  1   41.431  ? 108  GLN A HG3  1 c 
ATOM   1363  H  HE21 . GLN A 1 102 ? 36.086  3.263   12      1   38.09   ? 108  GLN A HE21 1 c 
ATOM   1364  H  HE22 . GLN A 1 102 ? 36.774  3.966   10.825  1   38.098  ? 108  GLN A HE22 1 c 
ATOM   1365  N  N    . ASN A 1 103 ? 40.817  5.877   7.932   1   41.753  ? 109  ASN A N    1 ? 
ATOM   1366  C  CA   . ASN A 1 103 ? 40.751  7.004   7.02    1   42.153  ? 109  ASN A CA   1 ? 
ATOM   1367  C  C    . ASN A 1 103 ? 41.508  6.698   5.721   1   40.603  ? 109  ASN A C    1 ? 
ATOM   1368  O  O    . ASN A 1 103 ? 40.942  6.919   4.665   1   41.259  ? 109  ASN A O    1 ? 
ATOM   1369  C  CB   . ASN A 1 103 ? 41.216  8.281   7.7     1   46.376  ? 109  ASN A CB   1 ? 
ATOM   1370  C  CG   . ASN A 1 103 ? 40.213  8.826   8.694   1   50.069  ? 109  ASN A CG   1 ? 
ATOM   1371  O  OD1  . ASN A 1 103 ? 39.109  8.299   8.87    1   50.246  ? 109  ASN A OD1  1 ? 
ATOM   1372  N  ND2  . ASN A 1 103 ? 40.606  9.879   9.388   1   53.351  ? 109  ASN A ND2  1 ? 
ATOM   1373  H  H    . ASN A 1 103 ? 41.254  5.975   8.728   1   41.137  ? 109  ASN A H    1 c 
ATOM   1374  H  HA   . ASN A 1 103 ? 39.805  7.136   6.782   1   42.568  ? 109  ASN A HA   1 c 
ATOM   1375  H  HB2  . ASN A 1 103 ? 42.061  8.109   8.161   1   46.118  ? 109  ASN A HB2  1 c 
ATOM   1376  H  HB3  . ASN A 1 103 ? 41.38   8.96    7.017   1   46.226  ? 109  ASN A HB3  1 c 
ATOM   1377  H  HD21 . ASN A 1 103 ? 40.055  10.252  9.975   1   52.292  ? 109  ASN A HD21 1 c 
ATOM   1378  H  HD22 . ASN A 1 103 ? 41.419  10.214  9.268   1   52.269  ? 109  ASN A HD22 1 c 
ATOM   1379  N  N    . PRO A 1 104 ? 42.793  6.242   5.716   1   38.005  ? 110  PRO A N    1 ? 
ATOM   1380  C  CA   . PRO A 1 104 ? 43.456  5.872   4.46    1   36.322  ? 110  PRO A CA   1 ? 
ATOM   1381  C  C    . PRO A 1 104 ? 42.877  4.634   3.79    1   35.077  ? 110  PRO A C    1 ? 
ATOM   1382  O  O    . PRO A 1 104 ? 42.885  4.507   2.556   1   38.906  ? 110  PRO A O    1 ? 
ATOM   1383  C  CB   . PRO A 1 104 ? 44.931  5.714   4.839   1   34.19   ? 110  PRO A CB   1 ? 
ATOM   1384  C  CG   . PRO A 1 104 ? 44.913  5.415   6.334   1   33.339  ? 110  PRO A CG   1 ? 
ATOM   1385  C  CD   . PRO A 1 104 ? 43.724  6.191   6.862   1   38.171  ? 110  PRO A CD   1 ? 
ATOM   1386  H  HA   . PRO A 1 104 ? 43.371  6.639   3.839   1   36.037  ? 110  PRO A HA   1 c 
ATOM   1387  H  HB2  . PRO A 1 104 ? 45.346  4.974   4.338   1   34.462  ? 110  PRO A HB2  1 c 
ATOM   1388  H  HB3  . PRO A 1 104 ? 45.431  6.543   4.654   1   34.46   ? 110  PRO A HB3  1 c 
ATOM   1389  H  HG2  . PRO A 1 104 ? 44.801  4.455   6.497   1   34.579  ? 110  PRO A HG2  1 c 
ATOM   1390  H  HG3  . PRO A 1 104 ? 45.742  5.715   6.761   1   34.603  ? 110  PRO A HG3  1 c 
ATOM   1391  H  HD2  . PRO A 1 104 ? 43.318  5.729   7.627   1   37.046  ? 110  PRO A HD2  1 c 
ATOM   1392  H  HD3  . PRO A 1 104 ? 43.991  7.095   7.139   1   37.002  ? 110  PRO A HD3  1 c 
ATOM   1393  N  N    . TYR A 1 105 ? 42.371  3.711   4.601   1   28.838  ? 111  TYR A N    1 ? 
ATOM   1394  C  CA   . TYR A 1 105 ? 41.762  2.514   4.047   1   28.72   ? 111  TYR A CA   1 ? 
ATOM   1395  C  C    . TYR A 1 105 ? 40.54   2.849   3.196   1   30.496  ? 111  TYR A C    1 ? 
ATOM   1396  O  O    . TYR A 1 105 ? 40.446  2.4     2.061   1   33.368  ? 111  TYR A O    1 ? 
ATOM   1397  C  CB   . TYR A 1 105 ? 41.472  1.588   5.229   1   28.501  ? 111  TYR A CB   1 ? 
ATOM   1398  C  CG   . TYR A 1 105 ? 40.622  0.352   5.021   1   28.296  ? 111  TYR A CG   1 ? 
ATOM   1399  C  CD1  . TYR A 1 105 ? 39.249  0.45    5.122   1   30.334  ? 111  TYR A CD1  1 ? 
ATOM   1400  C  CD2  . TYR A 1 105 ? 41.169  -0.9    4.728   1   29.69   ? 111  TYR A CD2  1 ? 
ATOM   1401  C  CE1  . TYR A 1 105 ? 38.43   -0.646  4.955   1   29.585  ? 111  TYR A CE1  1 ? 
ATOM   1402  C  CE2  . TYR A 1 105 ? 40.355  -2.03   4.654   1   26.76   ? 111  TYR A CE2  1 ? 
ATOM   1403  C  CZ   . TYR A 1 105 ? 38.979  -1.889  4.73    1   32.67   ? 111  TYR A CZ   1 ? 
ATOM   1404  O  OH   . TYR A 1 105 ? 38.064  -2.924  4.626   1   38.311  ? 111  TYR A OH   1 ? 
ATOM   1405  H  H    . TYR A 1 105 ? 42.411  3.818   5.508   1   30.253  ? 111  TYR A H    1 c 
ATOM   1406  H  HA   . TYR A 1 105 ? 42.433  2.069   3.464   1   29.219  ? 111  TYR A HA   1 c 
ATOM   1407  H  HB2  . TYR A 1 105 ? 42.337  1.3     5.597   1   28.508  ? 111  TYR A HB2  1 c 
ATOM   1408  H  HB3  . TYR A 1 105 ? 41.045  2.129   5.931   1   28.527  ? 111  TYR A HB3  1 c 
ATOM   1409  H  HD1  . TYR A 1 105 ? 38.859  1.292   5.293   1   29.686  ? 111  TYR A HD1  1 c 
ATOM   1410  H  HD2  . TYR A 1 105 ? 42.107  -1.003  4.706   1   28.712  ? 111  TYR A HD2  1 c 
ATOM   1411  H  HE1  . TYR A 1 105 ? 37.498  -0.555  5.05    1   30.488  ? 111  TYR A HE1  1 c 
ATOM   1412  H  HE2  . TYR A 1 105 ? 40.731  -2.872  4.459   1   28.773  ? 111  TYR A HE2  1 c 
ATOM   1413  H  HH   . TYR A 1 105 ? 37.822  -3.02   3.795   0   38.87   ? 111  TYR A HH   1 c 
ATOM   1414  N  N    . GLU A 1 106 ? 39.624  3.647   3.747   1   30.474  ? 112  GLU A N    1 ? 
ATOM   1415  C  CA   . GLU A 1 106 ? 38.444  4.113   3.047   1   27.903  ? 112  GLU A CA   1 ? 
ATOM   1416  C  C    . GLU A 1 106 ? 38.798  4.925   1.813   1   27.92   ? 112  GLU A C    1 ? 
ATOM   1417  O  O    . GLU A 1 106 ? 38.093  4.79    0.801   1   32.045  ? 112  GLU A O    1 ? 
ATOM   1418  C  CB   . GLU A 1 106 ? 37.561  4.995   3.941   1   34.254  ? 112  GLU A CB   1 ? 
ATOM   1419  C  CG   . GLU A 1 106 ? 36.857  4.219   5.043   1   42.981  ? 112  GLU A CG   1 ? 
ATOM   1420  C  CD   . GLU A 1 106 ? 35.962  3.099   4.541   1   47.87   ? 112  GLU A CD   1 ? 
ATOM   1421  O  OE1  . GLU A 1 106 ? 35.645  2.313   5.472   1   44.968  ? 112  GLU A OE1  1 ? 
ATOM   1422  O  OE2  . GLU A 1 106 ? 35.587  3.008   3.321   1   41.72   ? 112  GLU A OE2  1 ? 
ATOM   1423  H  H    . GLU A 1 106 ? 39.744  3.913   4.614   1   29.887  ? 112  GLU A H    1 c 
ATOM   1424  H  HA   . GLU A 1 106 ? 37.928  3.321   2.758   1   29.612  ? 112  GLU A HA   1 c 
ATOM   1425  H  HB2  . GLU A 1 106 ? 38.119  5.692   4.347   1   34.435  ? 112  GLU A HB2  1 c 
ATOM   1426  H  HB3  . GLU A 1 106 ? 36.887  5.438   3.384   1   34.405  ? 112  GLU A HB3  1 c 
ATOM   1427  H  HG2  . GLU A 1 106 ? 37.529  3.832   5.641   1   41.83   ? 112  GLU A HG2  1 c 
ATOM   1428  H  HG3  . GLU A 1 106 ? 36.311  4.839   5.572   1   41.831  ? 112  GLU A HG3  1 c 
ATOM   1429  N  N    . ALA A 1 107 ? 39.789  5.842   1.929   1   24.869  ? 113  ALA A N    1 ? 
ATOM   1430  C  CA   . ALA A 1 107 ? 40.181  6.626   0.765   1   27.749  ? 113  ALA A CA   1 ? 
ATOM   1431  C  C    . ALA A 1 107 ? 40.624  5.706   -0.362  1   26.49   ? 113  ALA A C    1 ? 
ATOM   1432  O  O    . ALA A 1 107 ? 40.18   5.842   -1.504  1   29.515  ? 113  ALA A O    1 ? 
ATOM   1433  C  CB   . ALA A 1 107 ? 41.282  7.621   1.12    1   28.477  ? 113  ALA A CB   1 ? 
ATOM   1434  H  H    . ALA A 1 107 ? 40.211  5.976   2.728   1   26.251  ? 113  ALA A H    1 c 
ATOM   1435  H  HA   . ALA A 1 107 ? 39.381  7.131   0.452   1   27.081  ? 113  ALA A HA   1 c 
ATOM   1436  H  HB1  . ALA A 1 107 ? 41.003  8.16    1.88    1   28.352  ? 113  ALA A HB1  1 c 
ATOM   1437  H  HB2  . ALA A 1 107 ? 42.096  7.141   1.348   1   28.455  ? 113  ALA A HB2  1 c 
ATOM   1438  H  HB3  . ALA A 1 107 ? 41.452  8.203   0.36    1   28.539  ? 113  ALA A HB3  1 c 
ATOM   1439  N  N    . ASN A 1 108 ? 41.454  4.71    -0.022  1   26.874  ? 114  ASN A N    1 ? 
ATOM   1440  C  CA   . ASN A 1 108 ? 41.886  3.763   -1.024  1   30.777  ? 114  ASN A CA   1 ? 
ATOM   1441  C  C    . ASN A 1 108 ? 40.699  3.05    -1.683  1   29.221  ? 114  ASN A C    1 ? 
ATOM   1442  O  O    . ASN A 1 108 ? 40.664  2.901   -2.881  1   29.006  ? 114  ASN A O    1 ? 
ATOM   1443  C  CB   . ASN A 1 108 ? 42.846  2.747   -0.438  1   26.365  ? 114  ASN A CB   1 ? 
ATOM   1444  C  CG   . ASN A 1 108 ? 44.19   3.338   -0.125  1   32.612  ? 114  ASN A CG   1 ? 
ATOM   1445  O  OD1  . ASN A 1 108 ? 44.542  4.421   -0.619  1   31.038  ? 114  ASN A OD1  1 ? 
ATOM   1446  N  ND2  . ASN A 1 108 ? 44.964  2.617   0.679   1   34.851  ? 114  ASN A ND2  1 ? 
ATOM   1447  H  H    . ASN A 1 108 ? 41.755  4.627   0.837   1   27.619  ? 114  ASN A H    1 c 
ATOM   1448  H  HA   . ASN A 1 108 ? 42.37   4.258   -1.724  1   28.872  ? 114  ASN A HA   1 c 
ATOM   1449  H  HB2  . ASN A 1 108 ? 42.46   2.38    0.382   1   28.735  ? 114  ASN A HB2  1 c 
ATOM   1450  H  HB3  . ASN A 1 108 ? 42.961  2.011   -1.072  1   28.699  ? 114  ASN A HB3  1 c 
ATOM   1451  H  HD21 . ASN A 1 108 ? 45.757  2.929   0.924   1   34.096  ? 114  ASN A HD21 1 c 
ATOM   1452  H  HD22 . ASN A 1 108 ? 44.69   1.825   0.97    1   34.029  ? 114  ASN A HD22 1 c 
ATOM   1453  N  N    . ARG A 1 109 ? 39.755  2.573   -0.88   1   32.724  ? 115  ARG A N    1 ? 
ATOM   1454  C  CA   . ARG A 1 109 ? 38.621  1.758   -1.31   1   34.951  ? 115  ARG A CA   1 ? 
ATOM   1455  C  C    . ARG A 1 109 ? 37.621  2.552   -2.17   1   34.31   ? 115  ARG A C    1 ? 
ATOM   1456  O  O    . ARG A 1 109 ? 37.147  2.122   -3.232  1   30.133  ? 115  ARG A O    1 ? 
ATOM   1457  C  CB   . ARG A 1 109 ? 38.016  1.415   0.062   1   37.847  ? 115  ARG A CB   1 ? 
ATOM   1458  C  CG   . ARG A 1 109 ? 37.485  0.027   0.218   1   39.801  ? 115  ARG A CG   1 ? 
ATOM   1459  C  CD   . ARG A 1 109 ? 37.257  -0.294  1.647   1   41.229  ? 115  ARG A CD   1 ? 
ATOM   1460  N  NE   . ARG A 1 109 ? 36.125  0.294   2.362   1   39.102  ? 115  ARG A NE   1 ? 
ATOM   1461  C  CZ   . ARG A 1 109 ? 35.321  -0.452  3.102   1   37.324  ? 115  ARG A CZ   1 ? 
ATOM   1462  N  NH1  . ARG A 1 109 ? 34.62   0.087   4.048   1   37.508  ? 115  ARG A NH1  1 ? 
ATOM   1463  N  NH2  . ARG A 1 109 ? 35.299  -1.758  3.001   1   39.176  ? 115  ARG A NH2  1 ? 
ATOM   1464  H  H    . ARG A 1 109 ? 39.82   2.779   0.008   1   32.372  ? 115  ARG A H    1 c 
ATOM   1465  H  HA   . ARG A 1 109 ? 38.945  0.955   -1.792  1   34.88   ? 115  ARG A HA   1 c 
ATOM   1466  H  HB2  . ARG A 1 109 ? 38.694  1.562   0.753   1   37.527  ? 115  ARG A HB2  1 c 
ATOM   1467  H  HB3  . ARG A 1 109 ? 37.281  2.042   0.24    1   37.533  ? 115  ARG A HB3  1 c 
ATOM   1468  H  HG2  . ARG A 1 109 ? 36.642  -0.057  -0.273  1   39.628  ? 115  ARG A HG2  1 c 
ATOM   1469  H  HG3  . ARG A 1 109 ? 38.13   -0.614  -0.157  1   39.66   ? 115  ARG A HG3  1 c 
ATOM   1470  H  HD2  . ARG A 1 109 ? 37.185  -1.268  1.7     1   40.337  ? 115  ARG A HD2  1 c 
ATOM   1471  H  HD3  . ARG A 1 109 ? 38.076  -0.054  2.127   1   40.339  ? 115  ARG A HD3  1 c 
ATOM   1472  H  HE   . ARG A 1 109 ? 35.978  1.15    2.295   1   39.121  ? 115  ARG A HE   1 c 
ATOM   1473  H  HH11 . ARG A 1 109 ? 34.544  0.963   4.098   1   37.571  ? 115  ARG A HH11 1 c 
ATOM   1474  H  HH12 . ARG A 1 109 ? 34.216  -0.427  4.644   1   37.492  ? 115  ARG A HH12 1 c 
ATOM   1475  H  HH21 . ARG A 1 109 ? 35.053  -2.134  2.239   1   38.498  ? 115  ARG A HH21 1 c 
ATOM   1476  H  HH22 . ARG A 1 109 ? 35.538  -2.254  3.691   1   38.407  ? 115  ARG A HH22 1 c 
ATOM   1477  N  N    . LYS A 1 110 ? 37.314  3.764   -1.706  1   33.655  ? 116  LYS A N    1 ? 
ATOM   1478  C  CA   . LYS A 1 110 ? 36.437  4.651   -2.444  1   33.387  ? 116  LYS A CA   1 ? 
ATOM   1479  C  C    . LYS A 1 110 ? 37.048  5.024   -3.787  1   31.657  ? 116  LYS A C    1 ? 
ATOM   1480  O  O    . LYS A 1 110 ? 36.299  5.298   -4.721  1   30.949  ? 116  LYS A O    1 ? 
ATOM   1481  C  CB   . LYS A 1 110 ? 36.172  5.93    -1.642  1   31.833  ? 116  LYS A CB   1 ? 
ATOM   1482  C  CG   . LYS A 1 110 ? 35.314  5.677   -0.4    1   39.042  ? 116  LYS A CG   1 ? 
ATOM   1483  C  CD   . LYS A 1 110 ? 35.039  6.902   0.456   1   48.571  ? 116  LYS A CD   1 ? 
ATOM   1484  C  CE   . LYS A 1 110 ? 33.87   6.602   1.371   1   67.054  ? 116  LYS A CE   1 ? 
ATOM   1485  N  NZ   . LYS A 1 110 ? 33.834  7.507   2.524   1   71.93   ? 116  LYS A NZ   1 ? 
ATOM   1486  H  H    . LYS A 1 110 ? 37.659  4.047   -0.909  1   33.82   ? 116  LYS A H    1 c 
ATOM   1487  H  HA   . LYS A 1 110 ? 35.578  4.183   -2.602  1   32.816  ? 116  LYS A HA   1 c 
ATOM   1488  H  HB2  . LYS A 1 110 ? 37.028  6.319   -1.361  1   33.708  ? 116  LYS A HB2  1 c 
ATOM   1489  H  HB3  . LYS A 1 110 ? 35.716  6.583   -2.215  1   33.698  ? 116  LYS A HB3  1 c 
ATOM   1490  H  HG2  . LYS A 1 110 ? 34.456  5.3     -0.693  1   39.256  ? 116  LYS A HG2  1 c 
ATOM   1491  H  HG3  . LYS A 1 110 ? 35.758  4.999   0.152   1   39.087  ? 116  LYS A HG3  1 c 
ATOM   1492  H  HD2  . LYS A 1 110 ? 35.831  7.118   0.995   1   49.779  ? 116  LYS A HD2  1 c 
ATOM   1493  H  HD3  . LYS A 1 110 ? 34.82   7.669   -0.118  1   49.779  ? 116  LYS A HD3  1 c 
ATOM   1494  H  HE2  . LYS A 1 110 ? 33.039  6.698   0.873   1   63.002  ? 116  LYS A HE2  1 c 
ATOM   1495  H  HE3  . LYS A 1 110 ? 33.928  5.683   1.69    1   63.121  ? 116  LYS A HE3  1 c 
ATOM   1496  H  HZ1  . LYS A 1 110 ? 33.827  8.367   2.239   1   70.393  ? 116  LYS A HZ1  1 c 
ATOM   1497  H  HZ2  . LYS A 1 110 ? 34.566  7.372   3.041   1   70.393  ? 116  LYS A HZ2  1 c 
ATOM   1498  H  HZ3  . LYS A 1 110 ? 33.09   7.349   3.015   1   70.393  ? 116  LYS A HZ3  1 c 
ATOM   1499  N  N    . ALA A 1 111 ? 38.382  5.091   -3.87   1   32.626  ? 117  ALA A N    1 ? 
ATOM   1500  C  CA   . ALA A 1 111 ? 39.026  5.534   -5.116  1   35.431  ? 117  ALA A CA   1 ? 
ATOM   1501  C  C    . ALA A 1 111 ? 38.759  4.491   -6.183  1   31.77   ? 117  ALA A C    1 ? 
ATOM   1502  O  O    . ALA A 1 111 ? 38.406  4.814   -7.32   1   31.167  ? 117  ALA A O    1 ? 
ATOM   1503  C  CB   . ALA A 1 111 ? 40.508  5.724   -4.952  1   33.381  ? 117  ALA A CB   1 ? 
ATOM   1504  H  H    . ALA A 1 111 ? 38.903  4.873   -3.151  1   33.007  ? 117  ALA A H    1 c 
ATOM   1505  H  HA   . ALA A 1 111 ? 38.61   6.394   -5.401  1   33.809  ? 117  ALA A HA   1 c 
ATOM   1506  H  HB1  . ALA A 1 111 ? 40.678  6.386   -4.262  1   33.972  ? 117  ALA A HB1  1 c 
ATOM   1507  H  HB2  . ALA A 1 111 ? 40.919  4.881   -4.697  1   33.951  ? 117  ALA A HB2  1 c 
ATOM   1508  H  HB3  . ALA A 1 111 ? 40.894  6.028   -5.791  1   33.972  ? 117  ALA A HB3  1 c 
ATOM   1509  N  N    . ILE A 1 112 ? 38.927  3.235   -5.756  1   30.758  ? 118  ILE A N    1 ? 
ATOM   1510  C  CA   . ILE A 1 112 ? 38.704  2.102   -6.62   1   33.431  ? 118  ILE A CA   1 ? 
ATOM   1511  C  C    . ILE A 1 112 ? 37.251  2.051   -7.107  1   33.477  ? 118  ILE A C    1 ? 
ATOM   1512  O  O    . ILE A 1 112 ? 37.009  1.79    -8.29   1   27.321  ? 118  ILE A O    1 ? 
ATOM   1513  C  CB   . ILE A 1 112 ? 39.109  0.795   -5.934  1   29.203  ? 118  ILE A CB   1 ? 
ATOM   1514  C  CG1  . ILE A 1 112 ? 40.593  0.713   -5.744  1   30.608  ? 118  ILE A CG1  1 ? 
ATOM   1515  C  CG2  . ILE A 1 112 ? 38.578  -0.399  -6.728  1   30.77   ? 118  ILE A CG2  1 ? 
ATOM   1516  C  CD1  . ILE A 1 112 ? 41.049  -0.441  -4.85   1   32.815  ? 118  ILE A CD1  1 ? 
ATOM   1517  H  H    . ILE A 1 112 ? 39.197  3.085   -4.896  1   31.586  ? 118  ILE A H    1 c 
ATOM   1518  H  HA   . ILE A 1 112 ? 39.277  2.213   -7.404  1   32.08   ? 118  ILE A HA   1 c 
ATOM   1519  H  HB   . ILE A 1 112 ? 38.692  0.779   -5.05   1   30.514  ? 118  ILE A HB   1 c 
ATOM   1520  H  HG12 . ILE A 1 112 ? 41.016  0.617   -6.621  1   30.775  ? 118  ILE A HG12 1 c 
ATOM   1521  H  HG13 . ILE A 1 112 ? 40.905  1.554   -5.353  1   30.85   ? 118  ILE A HG13 1 c 
ATOM   1522  H  HG21 . ILE A 1 112 ? 38.941  -1.223  -6.363  1   30.336  ? 118  ILE A HG21 1 c 
ATOM   1523  H  HG22 . ILE A 1 112 ? 38.845  -0.316  -7.66   1   30.326  ? 118  ILE A HG22 1 c 
ATOM   1524  H  HG23 . ILE A 1 112 ? 37.608  -0.426  -6.672  1   30.33   ? 118  ILE A HG23 1 c 
ATOM   1525  H  HD11 . ILE A 1 112 ? 40.55   -0.421  -4.012  1   32.147  ? 118  ILE A HD11 1 c 
ATOM   1526  H  HD12 . ILE A 1 112 ? 42.002  -0.345  -4.661  1   32.147  ? 118  ILE A HD12 1 c 
ATOM   1527  H  HD13 . ILE A 1 112 ? 40.894  -1.293  -5.3    1   32.132  ? 118  ILE A HD13 1 c 
ATOM   1528  N  N    . ASN A 1 113 ? 36.3    2.245   -6.193  1   34.592  ? 119  ASN A N    1 ? 
ATOM   1529  C  CA   . ASN A 1 113 ? 34.884  2.125   -6.548  1   35.782  ? 119  ASN A CA   1 ? 
ATOM   1530  C  C    . ASN A 1 113 ? 34.527  3.228   -7.545  1   32.206  ? 119  ASN A C    1 ? 
ATOM   1531  O  O    . ASN A 1 113 ? 33.841  2.958   -8.522  1   32.78   ? 119  ASN A O    1 ? 
ATOM   1532  C  CB   . ASN A 1 113 ? 33.951  2.183   -5.338  1   32.961  ? 119  ASN A CB   1 ? 
ATOM   1533  C  CG   . ASN A 1 113 ? 32.521  1.778   -5.635  1   31.14   ? 119  ASN A CG   1 ? 
ATOM   1534  O  OD1  . ASN A 1 113 ? 32.257  0.814   -6.356  1   30.527  ? 119  ASN A OD1  1 ? 
ATOM   1535  N  ND2  . ASN A 1 113 ? 31.567  2.562   -5.163  1   38.344  ? 119  ASN A ND2  1 ? 
ATOM   1536  H  H    . ASN A 1 113 ? 36.527  2.451   -5.332  1   34.537  ? 119  ASN A H    1 c 
ATOM   1537  H  HA   . ASN A 1 113 ? 34.75   1.254   -6.984  1   34.271  ? 119  ASN A HA   1 c 
ATOM   1538  H  HB2  . ASN A 1 113 ? 34.304  1.595   -4.641  1   33.155  ? 119  ASN A HB2  1 c 
ATOM   1539  H  HB3  . ASN A 1 113 ? 33.953  3.095   -4.984  1   33.191  ? 119  ASN A HB3  1 c 
ATOM   1540  H  HD21 . ASN A 1 113 ? 30.718  2.391   -5.361  1   35.905  ? 119  ASN A HD21 1 c 
ATOM   1541  H  HD22 . ASN A 1 113 ? 31.769  3.258   -4.651  1   35.903  ? 119  ASN A HD22 1 c 
ATOM   1542  N  N    . ALA A 1 114 ? 35.042  4.442   -7.32   1   35.087  ? 120  ALA A N    1 ? 
ATOM   1543  C  CA   . ALA A 1 114 ? 34.76   5.564   -8.211  1   36.43   ? 120  ALA A CA   1 ? 
ATOM   1544  C  C    . ALA A 1 114 ? 35.454  5.361   -9.561  1   36.178  ? 120  ALA A C    1 ? 
ATOM   1545  O  O    . ALA A 1 114 ? 34.864  5.691   -10.586 1   35.014  ? 120  ALA A O    1 ? 
ATOM   1546  C  CB   . ALA A 1 114 ? 35.162  6.878   -7.552  1   35.599  ? 120  ALA A CB   1 ? 
ATOM   1547  H  H    . ALA A 1 114 ? 35.576  4.579   -6.591  1   34.68   ? 120  ALA A H    1 c 
ATOM   1548  H  HA   . ALA A 1 114 ? 33.777  5.582   -8.376  1   35.924  ? 120  ALA A HA   1 c 
ATOM   1549  H  HB1  . ALA A 1 114 ? 34.659  6.998   -6.728  1   35.842  ? 120  ALA A HB1  1 c 
ATOM   1550  H  HB2  . ALA A 1 114 ? 36.112  6.865   -7.348  1   35.842  ? 120  ALA A HB2  1 c 
ATOM   1551  H  HB3  . ALA A 1 114 ? 34.972  7.617   -8.154  1   35.842  ? 120  ALA A HB3  1 c 
ATOM   1552  N  N    . LEU A 1 115 ? 36.669  4.769   -9.593  1   35.283  ? 121  LEU A N    1 ? 
ATOM   1553  C  CA   . LEU A 1 115 ? 37.325  4.492   -10.889 1   31.827  ? 121  LEU A CA   1 ? 
ATOM   1554  C  C    . LEU A 1 115 ? 36.517  3.467   -11.669 1   32.317  ? 121  LEU A C    1 ? 
ATOM   1555  O  O    . LEU A 1 115 ? 36.376  3.589   -12.877 1   34.043  ? 121  LEU A O    1 ? 
ATOM   1556  C  CB   . LEU A 1 115 ? 38.776  4.01    -10.759 1   28.531  ? 121  LEU A CB   1 ? 
ATOM   1557  C  CG   . LEU A 1 115 ? 39.753  5.064   -10.235 1   28.167  ? 121  LEU A CG   1 ? 
ATOM   1558  C  CD1  . LEU A 1 115 ? 40.941  4.422   -9.52   1   30.451  ? 121  LEU A CD1  1 ? 
ATOM   1559  C  CD2  . LEU A 1 115 ? 40.182  5.934   -11.409 1   27.185  ? 121  LEU A CD2  1 ? 
ATOM   1560  H  H    . LEU A 1 115 ? 37.094  4.54    -8.817  1   34.7    ? 121  LEU A H    1 c 
ATOM   1561  H  HA   . LEU A 1 115 ? 37.322  5.336   -11.41  1   31.934  ? 121  LEU A HA   1 c 
ATOM   1562  H  HB2  . LEU A 1 115 ? 38.789  3.24    -10.145 1   29.285  ? 121  LEU A HB2  1 c 
ATOM   1563  H  HB3  . LEU A 1 115 ? 39.084  3.706   -11.644 1   29.26   ? 121  LEU A HB3  1 c 
ATOM   1564  H  HG   . LEU A 1 115 ? 39.273  5.639   -9.585  1   28.499  ? 121  LEU A HG   1 c 
ATOM   1565  H  HD11 . LEU A 1 115 ? 40.632  3.973   -8.715  1   29.764  ? 121  LEU A HD11 1 c 
ATOM   1566  H  HD12 . LEU A 1 115 ? 41.586  5.109   -9.279  1   29.765  ? 121  LEU A HD12 1 c 
ATOM   1567  H  HD13 . LEU A 1 115 ? 41.363  3.775   -10.109 1   29.775  ? 121  LEU A HD13 1 c 
ATOM   1568  H  HD21 . LEU A 1 115 ? 39.405  6.386   -11.779 1   27.518  ? 121  LEU A HD21 1 c 
ATOM   1569  H  HD22 . LEU A 1 115 ? 40.59   5.378   -12.094 1   27.506  ? 121  LEU A HD22 1 c 
ATOM   1570  H  HD23 . LEU A 1 115 ? 40.826  6.595   -11.105 1   27.546  ? 121  LEU A HD23 1 c 
ATOM   1571  N  N    . MET A 1 116 ? 35.959  2.466   -10.978 1   32.147  ? 122  MET A N    1 ? 
ATOM   1572  C  CA   . MET A 1 116 ? 35.161  1.441   -11.635 1   29.944  ? 122  MET A CA   1 ? 
ATOM   1573  C  C    . MET A 1 116 ? 33.89   2.072   -12.235 1   32.085  ? 122  MET A C    1 ? 
ATOM   1574  O  O    . MET A 1 116 ? 33.566  1.887   -13.415 1   34.966  ? 122  MET A O    1 ? 
ATOM   1575  C  CB   . MET A 1 116 ? 34.839  0.315   -10.641 1   32.377  ? 122  MET A CB   1 ? 
ATOM   1576  C  CG   . MET A 1 116 ? 33.691  -0.63   -11.063 1   33.555  ? 122  MET A CG   1 ? 
ATOM   1577  S  SD   . MET A 1 116 ? 33.672  -2.229  -10.207 1   34.292  ? 122  MET A SD   1 ? 
ATOM   1578  C  CE   . MET A 1 116 ? 33.887  -1.675  -8.51   1   35.988  ? 122  MET A CE   1 ? 
ATOM   1579  H  H    . MET A 1 116 ? 36.085  2.417   -10.075 1   31.71   ? 122  MET A H    1 c 
ATOM   1580  H  HA   . MET A 1 116 ? 35.699  1.069   -12.38  1   31.205  ? 122  MET A HA   1 c 
ATOM   1581  H  HB2  . MET A 1 116 ? 35.651  -0.219  -10.507 1   32.066  ? 122  MET A HB2  1 c 
ATOM   1582  H  HB3  . MET A 1 116 ? 34.609  0.721   -9.779  1   32.081  ? 122  MET A HB3  1 c 
ATOM   1583  H  HG2  . MET A 1 116 ? 32.836  -0.184  -10.898 1   33.402  ? 122  MET A HG2  1 c 
ATOM   1584  H  HG3  . MET A 1 116 ? 33.755  -0.798  -12.025 1   33.394  ? 122  MET A HG3  1 c 
ATOM   1585  H  HE1  . MET A 1 116 ? 33.81   -2.439  -7.909  1   35.552  ? 122  MET A HE1  1 c 
ATOM   1586  H  HE2  . MET A 1 116 ? 34.767  -1.27   -8.408  1   35.539  ? 122  MET A HE2  1 c 
ATOM   1587  H  HE3  . MET A 1 116 ? 33.198  -1.021  -8.293  1   35.553  ? 122  MET A HE3  1 c 
ATOM   1588  N  N    . LEU A 1 117 ? 33.179  2.89    -11.46  1   31.648  ? 123  LEU A N    1 ? 
ATOM   1589  C  CA   . LEU A 1 117 ? 31.952  3.509   -11.97  1   29.88   ? 123  LEU A CA   1 ? 
ATOM   1590  C  C    . LEU A 1 117 ? 32.245  4.423   -13.153 1   29.263  ? 123  LEU A C    1 ? 
ATOM   1591  O  O    . LEU A 1 117 ? 31.518  4.414   -14.159 1   33.159  ? 123  LEU A O    1 ? 
ATOM   1592  C  CB   . LEU A 1 117 ? 31.21   4.229   -10.84  1   29.464  ? 123  LEU A CB   1 ? 
ATOM   1593  C  CG   . LEU A 1 117 ? 30.898  3.339   -9.633  1   29.76   ? 123  LEU A CG   1 ? 
ATOM   1594  C  CD1  . LEU A 1 117 ? 30.334  4.077   -8.434  1   34.933  ? 123  LEU A CD1  1 ? 
ATOM   1595  C  CD2  . LEU A 1 117 ? 29.928  2.273   -10.094 1   29.31   ? 123  LEU A CD2  1 ? 
ATOM   1596  H  H    . LEU A 1 117 ? 33.461  3.08    -10.612 1   31.315  ? 123  LEU A H    1 c 
ATOM   1597  H  HA   . LEU A 1 117 ? 31.373  2.78    -12.307 1   30.048  ? 123  LEU A HA   1 c 
ATOM   1598  H  HB2  . LEU A 1 117 ? 31.763  4.987   -10.538 1   29.624  ? 123  LEU A HB2  1 c 
ATOM   1599  H  HB3  . LEU A 1 117 ? 30.364  4.583   -11.199 1   29.622  ? 123  LEU A HB3  1 c 
ATOM   1600  H  HG   . LEU A 1 117 ? 31.731  2.889   -9.351  1   30.55   ? 123  LEU A HG   1 c 
ATOM   1601  H  HD11 . LEU A 1 117 ? 30.97   4.751   -8.14   1   33.299  ? 123  LEU A HD11 1 c 
ATOM   1602  H  HD12 . LEU A 1 117 ? 30.173  3.448   -7.711  1   33.252  ? 123  LEU A HD12 1 c 
ATOM   1603  H  HD13 . LEU A 1 117 ? 29.498  4.508   -8.681  1   33.299  ? 123  LEU A HD13 1 c 
ATOM   1604  H  HD21 . LEU A 1 117 ? 30.384  1.646   -10.68  1   29.462  ? 123  LEU A HD21 1 c 
ATOM   1605  H  HD22 . LEU A 1 117 ? 29.191  2.687   -10.574 1   29.458  ? 123  LEU A HD22 1 c 
ATOM   1606  H  HD23 . LEU A 1 117 ? 29.58   1.795   -9.322  1   29.498  ? 123  LEU A HD23 1 c 
ATOM   1607  N  N    . ALA A 1 118 ? 33.365  5.144   -13.062 1   31.954  ? 124  ALA A N    1 ? 
ATOM   1608  C  CA   . ALA A 1 118 ? 33.777  6.056   -14.118 1   33.295  ? 124  ALA A CA   1 ? 
ATOM   1609  C  C    . ALA A 1 118 ? 34.108  5.283   -15.383 1   33.633  ? 124  ALA A C    1 ? 
ATOM   1610  O  O    . ALA A 1 118 ? 33.739  5.724   -16.46  1   34.2    ? 124  ALA A O    1 ? 
ATOM   1611  C  CB   . ALA A 1 118 ? 34.947  6.934   -13.677 1   34.563  ? 124  ALA A CB   1 ? 
ATOM   1612  H  H    . ALA A 1 118 ? 33.887  5.073   -12.315 1   31.59   ? 124  ALA A H    1 c 
ATOM   1613  H  HA   . ALA A 1 118 ? 33.001  6.649   -14.322 1   33.299  ? 124  ALA A HA   1 c 
ATOM   1614  H  HB1  . ALA A 1 118 ? 34.725  7.382   -12.844 1   34.248  ? 124  ALA A HB1  1 c 
ATOM   1615  H  HB2  . ALA A 1 118 ? 35.737  6.382   -13.543 1   34.201  ? 124  ALA A HB2  1 c 
ATOM   1616  H  HB3  . ALA A 1 118 ? 35.133  7.6     -14.36  1   34.201  ? 124  ALA A HB3  1 c 
ATOM   1617  N  N    . GLU A 1 119 ? 34.774  4.129   -15.261 1   34.926  ? 125  GLU A N    1 ? 
ATOM   1618  C  CA   . GLU A 1 119 ? 35.119  3.362   -16.44  1   32.596  ? 125  GLU A CA   1 ? 
ATOM   1619  C  C    . GLU A 1 119 ? 33.883  2.719   -17.078 1   34.692  ? 125  GLU A C    1 ? 
ATOM   1620  O  O    . GLU A 1 119 ? 33.787  2.579   -18.297 1   34.082  ? 125  GLU A O    1 ? 
ATOM   1621  C  CB   . GLU A 1 119 ? 36.21   2.357   -16.059 1   32.277  ? 125  GLU A CB   1 ? 
ATOM   1622  C  CG   . GLU A 1 119 ? 36.763  1.592   -17.259 1   30.764  ? 125  GLU A CG   1 ? 
ATOM   1623  C  CD   . GLU A 1 119 ? 37.286  2.454   -18.419 1   35.065  ? 125  GLU A CD   1 ? 
ATOM   1624  O  OE1  . GLU A 1 119 ? 37.042  2.061   -19.594 1   35.214  ? 125  GLU A OE1  1 ? 
ATOM   1625  O  OE2  . GLU A 1 119 ? 37.924  3.498   -18.158 1   36.232  ? 125  GLU A OE2  1 ? 
ATOM   1626  H  H    . GLU A 1 119 ? 35.018  3.819   -14.436 1   34.047  ? 125  GLU A H    1 c 
ATOM   1627  H  HA   . GLU A 1 119 ? 35.507  3.988   -17.102 1   33.395  ? 125  GLU A HA   1 c 
ATOM   1628  H  HB2  . GLU A 1 119 ? 36.94   2.835   -15.616 1   32      ? 125  GLU A HB2  1 c 
ATOM   1629  H  HB3  . GLU A 1 119 ? 35.839  1.717   -15.416 1   31.998  ? 125  GLU A HB3  1 c 
ATOM   1630  H  HG2  . GLU A 1 119 ? 37.495  1.016   -16.953 1   32.048  ? 125  GLU A HG2  1 c 
ATOM   1631  H  HG3  . GLU A 1 119 ? 36.06   1.003   -17.608 1   32.072  ? 125  GLU A HG3  1 c 
ATOM   1632  N  N    . LEU A 1 120 ? 32.923  2.261   -16.273 1   30.223  ? 126  LEU A N    1 ? 
ATOM   1633  C  CA   . LEU A 1 120 ? 31.686  1.76    -16.841 1   31.814  ? 126  LEU A CA   1 ? 
ATOM   1634  C  C    . LEU A 1 120 ? 30.932  2.884   -17.581 1   35.679  ? 126  LEU A C    1 ? 
ATOM   1635  O  O    . LEU A 1 120 ? 30.258  2.649   -18.581 1   34.37   ? 126  LEU A O    1 ? 
ATOM   1636  C  CB   . LEU A 1 120 ? 30.851  1.207   -15.697 1   34.404  ? 126  LEU A CB   1 ? 
ATOM   1637  C  CG   . LEU A 1 120 ? 31.367  -0.05   -15     1   33.78   ? 126  LEU A CG   1 ? 
ATOM   1638  C  CD1  . LEU A 1 120 ? 30.582  -0.35   -13.691 1   33.818  ? 126  LEU A CD1  1 ? 
ATOM   1639  C  CD2  . LEU A 1 120 ? 31.261  -1.206  -16.006 1   30.753  ? 126  LEU A CD2  1 ? 
ATOM   1640  H  H    . LEU A 1 120 ? 33.039  2.256   -15.367 1   31.681  ? 126  LEU A H    1 c 
ATOM   1641  H  HA   . LEU A 1 120 ? 31.898  1.035   -17.481 1   32.617  ? 126  LEU A HA   1 c 
ATOM   1642  H  HB2  . LEU A 1 120 ? 30.755  1.916   -15.02  1   33.634  ? 126  LEU A HB2  1 c 
ATOM   1643  H  HB3  . LEU A 1 120 ? 29.948  1.019   -16.043 1   33.629  ? 126  LEU A HB3  1 c 
ATOM   1644  H  HG   . LEU A 1 120 ? 32.323  0.083   -14.773 1   33.301  ? 126  LEU A HG   1 c 
ATOM   1645  H  HD11 . LEU A 1 120 ? 30.668  0.402   -13.081 1   33.807  ? 126  LEU A HD11 1 c 
ATOM   1646  H  HD12 . LEU A 1 120 ? 30.942  -1.149  -13.272 1   33.807  ? 126  LEU A HD12 1 c 
ATOM   1647  H  HD13 . LEU A 1 120 ? 29.643  -0.49   -13.901 1   33.807  ? 126  LEU A HD13 1 c 
ATOM   1648  H  HD21 . LEU A 1 120 ? 31.895  -1.069  -16.73  1   31.635  ? 126  LEU A HD21 1 c 
ATOM   1649  H  HD22 . LEU A 1 120 ? 30.36   -1.242  -16.368 1   31.668  ? 126  LEU A HD22 1 c 
ATOM   1650  H  HD23 . LEU A 1 120 ? 31.462  -2.045  -15.558 1   31.646  ? 126  LEU A HD23 1 c 
ATOM   1651  N  N    . ALA A 1 121 ? 31.029  4.115   -17.094 1   35.146  ? 127  ALA A N    1 ? 
ATOM   1652  C  CA   . ALA A 1 121 ? 30.291  5.21    -17.706 1   38.153  ? 127  ALA A CA   1 ? 
ATOM   1653  C  C    . ALA A 1 121 ? 30.968  5.664   -18.999 1   41.517  ? 127  ALA A C    1 ? 
ATOM   1654  O  O    . ALA A 1 121 ? 30.305  5.916   -20.013 1   43.406  ? 127  ALA A O    1 ? 
ATOM   1655  C  CB   . ALA A 1 121 ? 30.158  6.358   -16.727 1   35.128  ? 127  ALA A CB   1 ? 
ATOM   1656  H  H    . ALA A 1 121 ? 31.552  4.283   -16.363 1   35.832  ? 127  ALA A H    1 c 
ATOM   1657  H  HA   . ALA A 1 121 ? 29.381  4.879   -17.937 1   37.572  ? 127  ALA A HA   1 c 
ATOM   1658  H  HB1  . ALA A 1 121 ? 29.682  6.058   -15.934 1   35.997  ? 127  ALA A HB1  1 c 
ATOM   1659  H  HB2  . ALA A 1 121 ? 31.041  6.673   -16.471 1   35.997  ? 127  ALA A HB2  1 c 
ATOM   1660  H  HB3  . ALA A 1 121 ? 29.665  7.086   -17.141 1   35.997  ? 127  ALA A HB3  1 c 
ATOM   1661  N  N    . GLU A 1 122 ? 32.3    5.738   -19.006 1   40.776  ? 128  GLU A N    1 ? 
ATOM   1662  C  CA   . GLU A 1 122 ? 32.977  6.269   -20.187 1   41.51   ? 128  GLU A CA   1 ? 
ATOM   1663  C  C    . GLU A 1 122 ? 33.346  5.14    -21.152 1   41.427  ? 128  GLU A C    1 ? 
ATOM   1664  O  O    . GLU A 1 122 ? 33.038  5.211   -22.337 1   43.445  ? 128  GLU A O    1 ? 
ATOM   1665  C  CB   . GLU A 1 122 ? 34.162  7.136   -19.764 1   40.608  ? 128  GLU A CB   1 ? 
ATOM   1666  C  CG   . GLU A 1 122 ? 34.971  7.681   -20.945 1   41.126  ? 128  GLU A CG   1 ? 
ATOM   1667  C  CD   . GLU A 1 122 ? 36.076  8.588   -20.452 1   38.784  ? 128  GLU A CD   1 ? 
ATOM   1668  O  OE1  . GLU A 1 122 ? 35.89   9.772   -20.68  1   42.96   ? 128  GLU A OE1  1 ? 
ATOM   1669  O  OE2  . GLU A 1 122 ? 37.018  8.16    -19.728 1   44.731  ? 128  GLU A OE2  1 ? 
ATOM   1670  H  H    . GLU A 1 122 ? 32.791  5.468   -18.284 1   41.051  ? 128  GLU A H    1 c 
ATOM   1671  H  HA   . GLU A 1 122 ? 32.344  6.868   -20.658 1   41.212  ? 128  GLU A HA   1 c 
ATOM   1672  H  HB2  . GLU A 1 122 ? 33.83   7.888   -19.234 1   40.984  ? 128  GLU A HB2  1 c 
ATOM   1673  H  HB3  . GLU A 1 122 ? 34.754  6.604   -19.191 1   40.94   ? 128  GLU A HB3  1 c 
ATOM   1674  H  HG2  . GLU A 1 122 ? 35.367  6.937   -21.447 1   40.468  ? 128  GLU A HG2  1 c 
ATOM   1675  H  HG3  . GLU A 1 122 ? 34.38   8.185   -21.545 1   40.478  ? 128  GLU A HG3  1 c 
ATOM   1676  N  N    . GLY A 1 123 ? 34.05   4.11    -20.654 1   39.931  ? 129  GLY A N    1 ? 
ATOM   1677  C  CA   . GLY A 1 123 ? 34.317  2.923   -21.456 1   39.022  ? 129  GLY A CA   1 ? 
ATOM   1678  C  C    . GLY A 1 123 ? 35.359  3.151   -22.555 1   39.364  ? 129  GLY A C    1 ? 
ATOM   1679  O  O    . GLY A 1 123 ? 35.33   2.454   -23.563 1   43.531  ? 129  GLY A O    1 ? 
ATOM   1680  H  H    . GLY A 1 123 ? 34.37   4.151   -19.799 1   40.089  ? 129  GLY A H    1 c 
ATOM   1681  H  HA2  . GLY A 1 123 ? 34.629  2.203   -20.859 1   39.309  ? 129  GLY A HA2  1 c 
ATOM   1682  H  HA3  . GLY A 1 123 ? 33.475  2.623   -21.868 1   39.319  ? 129  GLY A HA3  1 c 
ATOM   1683  N  N    . LYS A 1 124 ? 36.322  4.063   -22.331 1   40.221  ? 130  LYS A N    1 ? 
ATOM   1684  C  CA   . LYS A 1 124 ? 37.399  4.296   -23.286 1   41.947  ? 130  LYS A CA   1 ? 
ATOM   1685  C  C    . LYS A 1 124 ? 38.74   3.785   -22.78  1   45.655  ? 130  LYS A C    1 ? 
ATOM   1686  O  O    . LYS A 1 124 ? 39.729  4.066   -23.438 1   42.324  ? 130  LYS A O    1 ? 
ATOM   1687  C  CB   . LYS A 1 124 ? 37.57   5.78    -23.602 1   42.627  ? 130  LYS A CB   1 ? 
ATOM   1688  C  CG   . LYS A 1 124 ? 36.409  6.356   -24.43  1   44.774  ? 130  LYS A CG   1 ? 
ATOM   1689  C  CD   . LYS A 1 124 ? 36.262  7.856   -24.322 1   42.737  ? 130  LYS A CD   1 ? 
ATOM   1690  C  CE   . LYS A 1 124 ? 37.434  8.527   -24.946 1   53.423  ? 130  LYS A CE   1 ? 
ATOM   1691  N  NZ   . LYS A 1 124 ? 37.283  9.988   -25.037 1   60.637  ? 130  LYS A NZ   1 ? 
ATOM   1692  H  H    . LYS A 1 124 ? 36.305  4.555   -21.561 1   40.39   ? 130  LYS A H    1 c 
ATOM   1693  H  HA   . LYS A 1 124 ? 37.181  3.822   -24.128 1   42.374  ? 130  LYS A HA   1 c 
ATOM   1694  H  HB2  . LYS A 1 124 ? 37.636  6.281   -22.761 1   42.949  ? 130  LYS A HB2  1 c 
ATOM   1695  H  HB3  . LYS A 1 124 ? 38.404  5.914   -24.1   1   42.959  ? 130  LYS A HB3  1 c 
ATOM   1696  H  HG2  . LYS A 1 124 ? 36.549  6.116   -25.372 1   43.855  ? 130  LYS A HG2  1 c 
ATOM   1697  H  HG3  . LYS A 1 124 ? 35.574  5.933   -24.134 1   43.789  ? 130  LYS A HG3  1 c 
ATOM   1698  H  HD2  . LYS A 1 124 ? 35.441  8.14    -24.78  1   45.488  ? 130  LYS A HD2  1 c 
ATOM   1699  H  HD3  . LYS A 1 124 ? 36.204  8.115   -23.378 1   45.472  ? 130  LYS A HD3  1 c 
ATOM   1700  H  HE2  . LYS A 1 124 ? 38.233  8.331   -24.425 1   52.205  ? 130  LYS A HE2  1 c 
ATOM   1701  H  HE3  . LYS A 1 124 ? 37.568  8.172   -25.843 1   52.16   ? 130  LYS A HE3  1 c 
ATOM   1702  H  HZ1  . LYS A 1 124 ? 37.187  10.338  -24.207 1   58.317  ? 130  LYS A HZ1  1 c 
ATOM   1703  H  HZ2  . LYS A 1 124 ? 36.552  10.19   -25.533 1   58.317  ? 130  LYS A HZ2  1 c 
ATOM   1704  H  HZ3  . LYS A 1 124 ? 38.017  10.347  -25.429 1   58.317  ? 130  LYS A HZ3  1 c 
ATOM   1705  N  N    . GLY A 1 125 ? 38.761  3.103   -21.607 1   42.86   ? 131  GLY A N    1 ? 
ATOM   1706  C  CA   . GLY A 1 125 ? 39.958  2.497   -21.022 1   34.234  ? 131  GLY A CA   1 ? 
ATOM   1707  C  C    . GLY A 1 125 ? 40.861  3.485   -20.259 1   35.259  ? 131  GLY A C    1 ? 
ATOM   1708  O  O    . GLY A 1 125 ? 41.941  3.14    -19.805 1   34.508  ? 131  GLY A O    1 ? 
ATOM   1709  H  H    . GLY A 1 125 ? 37.976  3.012   -21.149 1   41.296  ? 131  GLY A H    1 c 
ATOM   1710  H  HA2  . GLY A 1 125 ? 39.677  1.78    -20.407 1   36.373  ? 131  GLY A HA2  1 c 
ATOM   1711  H  HA3  . GLY A 1 125 ? 40.481  2.078   -21.746 1   36.431  ? 131  GLY A HA3  1 c 
ATOM   1712  N  N    . ARG A 1 126 ? 40.388  4.702   -20.037 1   33.658  ? 132  ARG A N    1 ? 
ATOM   1713  C  CA   . ARG A 1 126 ? 41.19   5.761   -19.463 1   35.486  ? 132  ARG A CA   1 ? 
ATOM   1714  C  C    . ARG A 1 126 ? 41.362  5.629   -17.946 1   39.53   ? 132  ARG A C    1 ? 
ATOM   1715  O  O    . ARG A 1 126 ? 42.22   6.315   -17.362 1   36.697  ? 132  ARG A O    1 ? 
ATOM   1716  C  CB   . ARG A 1 126 ? 40.435  7.01    -19.935 1   41.935  ? 132  ARG A CB   1 ? 
ATOM   1717  C  CG   . ARG A 1 126 ? 40.907  8.357   -19.417 1   48.352  ? 132  ARG A CG   1 ? 
ATOM   1718  C  CD   . ARG A 1 126 ? 40.394  9.503   -20.292 1   49.868  ? 132  ARG A CD   1 ? 
ATOM   1719  N  NE   . ARG A 1 126 ? 39.063  9.971   -19.894 1   50.605  ? 132  ARG A NE   1 ? 
ATOM   1720  C  CZ   . ARG A 1 126 ? 38.797  11.072  -19.201 1   50.929  ? 132  ARG A CZ   1 ? 
ATOM   1721  N  NH1  . ARG A 1 126 ? 39.773  11.872  -18.818 1   49.902  ? 132  ARG A NH1  1 ? 
ATOM   1722  N  NH2  . ARG A 1 126 ? 37.542  11.396  -18.914 1   45.044  ? 132  ARG A NH2  1 ? 
ATOM   1723  H  H    . ARG A 1 126 ? 39.515  4.877   -20.239 1   34.665  ? 132  ARG A H    1 c 
ATOM   1724  H  HA   . ARG A 1 126 ? 42.085  5.745   -19.889 1   36.899  ? 132  ARG A HA   1 c 
ATOM   1725  H  HB2  . ARG A 1 126 ? 40.475  7.028   -20.916 1   41.784  ? 132  ARG A HB2  1 c 
ATOM   1726  H  HB3  . ARG A 1 126 ? 39.491  6.907   -19.687 1   41.615  ? 132  ARG A HB3  1 c 
ATOM   1727  H  HG2  . ARG A 1 126 ? 40.582  8.484   -18.497 1   47.131  ? 132  ARG A HG2  1 c 
ATOM   1728  H  HG3  . ARG A 1 126 ? 41.888  8.377   -19.403 1   47.125  ? 132  ARG A HG3  1 c 
ATOM   1729  H  HD2  . ARG A 1 126 ? 41.024  10.246  -20.248 1   49.718  ? 132  ARG A HD2  1 c 
ATOM   1730  H  HD3  . ARG A 1 126 ? 40.361  9.203   -21.222 1   49.592  ? 132  ARG A HD3  1 c 
ATOM   1731  H  HE   . ARG A 1 126 ? 38.387  9.486   -20.137 1   50.344  ? 132  ARG A HE   1 c 
ATOM   1732  H  HH11 . ARG A 1 126 ? 40.455  11.546  -18.353 1   50.21   ? 132  ARG A HH11 1 c 
ATOM   1733  H  HH12 . ARG A 1 126 ? 39.739  12.735  -19.025 1   50.215  ? 132  ARG A HH12 1 c 
ATOM   1734  H  HH21 . ARG A 1 126 ? 36.913  10.77   -18.903 1   46.786  ? 132  ARG A HH21 1 c 
ATOM   1735  H  HH22 . ARG A 1 126 ? 37.34   12.24   -18.73  1   46.787  ? 132  ARG A HH22 1 c 
ATOM   1736  N  N    . PHE A 1 127 ? 40.559  4.773   -17.281 1   32.738  ? 133  PHE A N    1 ? 
ATOM   1737  C  CA   . PHE A 1 127 ? 40.706  4.611   -15.843 1   32.707  ? 133  PHE A CA   1 ? 
ATOM   1738  C  C    . PHE A 1 127 ? 41.341  3.256   -15.516 1   34.17   ? 133  PHE A C    1 ? 
ATOM   1739  O  O    . PHE A 1 127 ? 41.407  2.878   -14.345 1   30.463  ? 133  PHE A O    1 ? 
ATOM   1740  C  CB   . PHE A 1 127 ? 39.358  4.778   -15.114 1   32.3    ? 133  PHE A CB   1 ? 
ATOM   1741  C  CG   . PHE A 1 127 ? 38.668  6.093   -15.455 1   31.635  ? 133  PHE A CG   1 ? 
ATOM   1742  C  CD1  . PHE A 1 127 ? 39.101  7.277   -14.9   1   33.29   ? 133  PHE A CD1  1 ? 
ATOM   1743  C  CD2  . PHE A 1 127 ? 37.626  6.145   -16.376 1   36.561  ? 133  PHE A CD2  1 ? 
ATOM   1744  C  CE1  . PHE A 1 127 ? 38.536  8.479   -15.269 1   32.938  ? 133  PHE A CE1  1 ? 
ATOM   1745  C  CE2  . PHE A 1 127 ? 37.032  7.349   -16.705 1   35.374  ? 133  PHE A CE2  1 ? 
ATOM   1746  C  CZ   . PHE A 1 127 ? 37.493  8.508   -16.141 1   34.045  ? 133  PHE A CZ   1 ? 
ATOM   1747  H  H    . PHE A 1 127 ? 39.913  4.299   -17.722 1   34.238  ? 133  PHE A H    1 c 
ATOM   1748  H  HA   . PHE A 1 127 ? 41.317  5.321   -15.512 1   32.962  ? 133  PHE A HA   1 c 
ATOM   1749  H  HB2  . PHE A 1 127 ? 38.77   4.032   -15.363 1   32.234  ? 133  PHE A HB2  1 c 
ATOM   1750  H  HB3  . PHE A 1 127 ? 39.514  4.739   -14.144 1   32.228  ? 133  PHE A HB3  1 c 
ATOM   1751  H  HD1  . PHE A 1 127 ? 39.833  7.269   -14.304 1   32.856  ? 133  PHE A HD1  1 c 
ATOM   1752  H  HD2  . PHE A 1 127 ? 37.308  5.347   -16.764 1   35.035  ? 133  PHE A HD2  1 c 
ATOM   1753  H  HE1  . PHE A 1 127 ? 38.835  9.279   -14.869 1   33.368  ? 133  PHE A HE1  1 c 
ATOM   1754  H  HE2  . PHE A 1 127 ? 36.316  7.372   -17.319 1   35.317  ? 133  PHE A HE2  1 c 
ATOM   1755  H  HZ   . PHE A 1 127 ? 37.089  9.331   -16.363 1   34.083  ? 133  PHE A HZ   1 c 
ATOM   1756  N  N    . ILE A 1 128 ? 41.715  2.488   -16.543 1   32.948  ? 134  ILE A N    1 ? 
ATOM   1757  C  CA   . ILE A 1 128 ? 42.083  1.085   -16.362 1   35.086  ? 134  ILE A CA   1 ? 
ATOM   1758  C  C    . ILE A 1 128 ? 43.428  1.023   -15.627 1   36.792  ? 134  ILE A C    1 ? 
ATOM   1759  O  O    . ILE A 1 128 ? 43.665  0.112   -14.841 1   37.182  ? 134  ILE A O    1 ? 
ATOM   1760  C  CB   . ILE A 1 128 ? 42.05   0.362   -17.732 1   31.121  ? 134  ILE A CB   1 ? 
ATOM   1761  C  CG1  . ILE A 1 128 ? 40.638  0.088   -18.138 1   36.013  ? 134  ILE A CG1  1 ? 
ATOM   1762  C  CG2  . ILE A 1 128 ? 42.853  -0.939  -17.806 1   33.453  ? 134  ILE A CG2  1 ? 
ATOM   1763  C  CD1  . ILE A 1 128 ? 40.009  -1.1    -17.419 1   36.315  ? 134  ILE A CD1  1 ? 
ATOM   1764  H  H    . ILE A 1 128 ? 41.753  2.846   -17.382 1   33.703  ? 134  ILE A H    1 c 
ATOM   1765  H  HA   . ILE A 1 128 ? 41.41   0.672   -15.788 1   34.241  ? 134  ILE A HA   1 c 
ATOM   1766  H  HB   . ILE A 1 128 ? 42.428  0.975   -18.393 1   33.17   ? 134  ILE A HB   1 c 
ATOM   1767  H  HG12 . ILE A 1 128 ? 40.098  0.886   -17.962 1   34.866  ? 134  ILE A HG12 1 c 
ATOM   1768  H  HG13 . ILE A 1 128 ? 40.617  -0.08   -19.102 1   34.872  ? 134  ILE A HG13 1 c 
ATOM   1769  H  HG21 . ILE A 1 128 ? 42.585  -1.444  -18.593 1   32.796  ? 134  ILE A HG21 1 c 
ATOM   1770  H  HG22 . ILE A 1 128 ? 42.688  -1.472  -17.01  1   32.783  ? 134  ILE A HG22 1 c 
ATOM   1771  H  HG23 . ILE A 1 128 ? 43.801  -0.734  -17.864 1   32.783  ? 134  ILE A HG23 1 c 
ATOM   1772  H  HD11 . ILE A 1 128 ? 40.396  -1.932  -17.751 1   36.205  ? 134  ILE A HD11 1 c 
ATOM   1773  H  HD12 . ILE A 1 128 ? 39.047  -1.103  -17.589 1   36.217  ? 134  ILE A HD12 1 c 
ATOM   1774  H  HD13 . ILE A 1 128 ? 40.165  -1.031  -16.458 1   36.201  ? 134  ILE A HD13 1 c 
ATOM   1775  N  N    . ASP A 1 129 ? 44.301  2.02    -15.844 1   34.322  ? 135  ASP A N    1 ? 
ATOM   1776  C  CA   . ASP A 1 129 ? 45.65   1.945   -15.308 1   33.853  ? 135  ASP A CA   1 ? 
ATOM   1777  C  C    . ASP A 1 129 ? 45.578  2.069   -13.784 1   35.716  ? 135  ASP A C    1 ? 
ATOM   1778  O  O    . ASP A 1 129 ? 46.285  1.36    -13.056 1   35.139  ? 135  ASP A O    1 ? 
ATOM   1779  C  CB   . ASP A 1 129 ? 46.603  2.964   -15.928 1   30.815  ? 135  ASP A CB   1 ? 
ATOM   1780  C  CG   . ASP A 1 129 ? 47.502  2.496   -17.078 1   33.054  ? 135  ASP A CG   1 ? 
ATOM   1781  O  OD1  . ASP A 1 129 ? 47.41   1.324   -17.52  1   36.865  ? 135  ASP A OD1  1 ? 
ATOM   1782  O  OD2  . ASP A 1 129 ? 48.345  3.29    -17.5   1   37.486  ? 135  ASP A OD2  1 ? 
ATOM   1783  H  H    . ASP A 1 129 ? 44.057  2.748   -16.338 1   34.722  ? 135  ASP A H    1 c 
ATOM   1784  H  HA   . ASP A 1 129 ? 46.009  1.054   -15.52  1   33.731  ? 135  ASP A HA   1 c 
ATOM   1785  H  HB2  . ASP A 1 129 ? 46.073  3.719   -16.259 1   32.03   ? 135  ASP A HB2  1 c 
ATOM   1786  H  HB3  . ASP A 1 129 ? 47.187  3.31    -15.221 1   32.021  ? 135  ASP A HB3  1 c 
ATOM   1787  N  N    . GLN A 1 130 ? 44.771  3.009   -13.316 1   29.089  ? 136  GLN A N    1 ? 
ATOM   1788  C  CA   . GLN A 1 130 ? 44.552  3.159   -11.897 1   30.771  ? 136  GLN A CA   1 ? 
ATOM   1789  C  C    . GLN A 1 130 ? 43.715  2.019   -11.309 1   30.165  ? 136  GLN A C    1 ? 
ATOM   1790  O  O    . GLN A 1 130 ? 43.85   1.695   -10.13  1   34.567  ? 136  GLN A O    1 ? 
ATOM   1791  C  CB   . GLN A 1 130 ? 43.89   4.521   -11.724 1   30.964  ? 136  GLN A CB   1 ? 
ATOM   1792  C  CG   . GLN A 1 130 ? 44.867  5.685   -11.696 1   34.314  ? 136  GLN A CG   1 ? 
ATOM   1793  C  CD   . GLN A 1 130 ? 45.657  5.757   -10.398 1   33.021  ? 136  GLN A CD   1 ? 
ATOM   1794  O  OE1  . GLN A 1 130 ? 46.557  4.947   -10.134 1   31.698  ? 136  GLN A OE1  1 ? 
ATOM   1795  N  NE2  . GLN A 1 130 ? 45.355  6.776   -9.598  1   36.081  ? 136  GLN A NE2  1 ? 
ATOM   1796  H  H    . GLN A 1 130 ? 44.35   3.577   -13.896 1   30.987  ? 136  GLN A H    1 c 
ATOM   1797  H  HA   . GLN A 1 130 ? 45.432  3.167   -11.446 1   30.457  ? 136  GLN A HA   1 c 
ATOM   1798  H  HB2  . GLN A 1 130 ? 43.25   4.661   -12.453 1   31.629  ? 136  GLN A HB2  1 c 
ATOM   1799  H  HB3  . GLN A 1 130 ? 43.386  4.517   -10.885 1   31.631  ? 136  GLN A HB3  1 c 
ATOM   1800  H  HG2  . GLN A 1 130 ? 45.497  5.596   -12.443 1   33.234  ? 136  GLN A HG2  1 c 
ATOM   1801  H  HG3  . GLN A 1 130 ? 44.375  6.524   -11.821 1   33.259  ? 136  GLN A HG3  1 c 
ATOM   1802  H  HE21 . GLN A 1 130 ? 45.815  6.897   -8.849  1   35.078  ? 136  GLN A HE21 1 c 
ATOM   1803  H  HE22 . GLN A 1 130 ? 44.697  7.333   -9.806  1   35.08   ? 136  GLN A HE22 1 c 
ATOM   1804  N  N    . LEU A 1 131 ? 42.812  1.429   -12.092 1   29.627  ? 137  LEU A N    1 ? 
ATOM   1805  C  CA   . LEU A 1 131 ? 42.084  0.273   -11.605 1   31.541  ? 137  LEU A CA   1 ? 
ATOM   1806  C  C    . LEU A 1 131 ? 43.131  -0.808  -11.31  1   32.454  ? 137  LEU A C    1 ? 
ATOM   1807  O  O    . LEU A 1 131 ? 43.058  -1.472  -10.262 1   33.908  ? 137  LEU A O    1 ? 
ATOM   1808  C  CB   . LEU A 1 131 ? 41.047  -0.239  -12.608 1   36.945  ? 137  LEU A CB   1 ? 
ATOM   1809  C  CG   . LEU A 1 131 ? 39.55   0.049   -12.399 1   47.736  ? 137  LEU A CG   1 ? 
ATOM   1810  C  CD1  . LEU A 1 131 ? 39.107  0.339   -10.99  1   44.829  ? 137  LEU A CD1  1 ? 
ATOM   1811  C  CD2  . LEU A 1 131 ? 39.014  1.085   -13.358 1   44.382  ? 137  LEU A CD2  1 ? 
ATOM   1812  H  H    . LEU A 1 131 ? 42.639  1.754   -12.928 1   30.301  ? 137  LEU A H    1 c 
ATOM   1813  H  HA   . LEU A 1 131 ? 41.634  0.518   -10.758 1   32.436  ? 137  LEU A HA   1 c 
ATOM   1814  H  HB2  . LEU A 1 131 ? 41.298  0.103   -13.496 1   37.694  ? 137  LEU A HB2  1 c 
ATOM   1815  H  HB3  . LEU A 1 131 ? 41.155  -1.215  -12.674 1   37.651  ? 137  LEU A HB3  1 c 
ATOM   1816  H  HG   . LEU A 1 131 ? 39.078  -0.789  -12.642 1   44.362  ? 137  LEU A HG   1 c 
ATOM   1817  H  HD11 . LEU A 1 131 ? 39.437  -0.357  -10.396 1   45.478  ? 137  LEU A HD11 1 c 
ATOM   1818  H  HD12 . LEU A 1 131 ? 38.137  0.362   -10.952 1   45.561  ? 137  LEU A HD12 1 c 
ATOM   1819  H  HD13 . LEU A 1 131 ? 39.463  1.198   -10.709 1   45.273  ? 137  LEU A HD13 1 c 
ATOM   1820  H  HD21 . LEU A 1 131 ? 39.206  0.814   -14.272 1   45.233  ? 137  LEU A HD21 1 c 
ATOM   1821  H  HD22 . LEU A 1 131 ? 39.434  1.942   -13.179 1   45.085  ? 137  LEU A HD22 1 c 
ATOM   1822  H  HD23 . LEU A 1 131 ? 38.052  1.167   -13.241 1   45.278  ? 137  LEU A HD23 1 c 
ATOM   1823  N  N    . ILE A 1 132 ? 44.09   -0.986  -12.241 1   27.943  ? 138  ILE A N    1 ? 
ATOM   1824  C  CA   . ILE A 1 132 ? 45.112  -2.031  -12.119 1   33.488  ? 138  ILE A CA   1 ? 
ATOM   1825  C  C    . ILE A 1 132 ? 45.942  -1.758  -10.869 1   30.699  ? 138  ILE A C    1 ? 
ATOM   1826  O  O    . ILE A 1 132 ? 46.164  -2.652  -10.061 1   27.982  ? 138  ILE A O    1 ? 
ATOM   1827  C  CB   . ILE A 1 132 ? 46.033  -2.082  -13.351 1   33.388  ? 138  ILE A CB   1 ? 
ATOM   1828  C  CG1  . ILE A 1 132 ? 45.31   -2.614  -14.564 1   32.95   ? 138  ILE A CG1  1 ? 
ATOM   1829  C  CG2  . ILE A 1 132 ? 47.303  -2.887  -13.047 1   32.002  ? 138  ILE A CG2  1 ? 
ATOM   1830  C  CD1  . ILE A 1 132 ? 46.028  -2.295  -15.868 1   35.969  ? 138  ILE A CD1  1 ? 
ATOM   1831  H  H    . ILE A 1 132 ? 44.104  -0.446  -12.978 1   30.204  ? 138  ILE A H    1 c 
ATOM   1832  H  HA   . ILE A 1 132 ? 44.667  -2.895  -12.022 1   31.799  ? 138  ILE A HA   1 c 
ATOM   1833  H  HB   . ILE A 1 132 ? 46.306  -1.166  -13.552 1   33.069  ? 138  ILE A HB   1 c 
ATOM   1834  H  HG12 . ILE A 1 132 ? 45.224  -3.586  -14.48  1   33.711  ? 138  ILE A HG12 1 c 
ATOM   1835  H  HG13 . ILE A 1 132 ? 44.409  -2.234  -14.593 1   33.689  ? 138  ILE A HG13 1 c 
ATOM   1836  H  HG21 . ILE A 1 132 ? 47.777  -3.076  -13.873 1   32.434  ? 138  ILE A HG21 1 c 
ATOM   1837  H  HG22 . ILE A 1 132 ? 47.063  -3.725  -12.616 1   32.399  ? 138  ILE A HG22 1 c 
ATOM   1838  H  HG23 . ILE A 1 132 ? 47.882  -2.376  -12.457 1   32.398  ? 138  ILE A HG23 1 c 
ATOM   1839  H  HD11 . ILE A 1 132 ? 46.086  -1.327  -15.979 1   35.044  ? 138  ILE A HD11 1 c 
ATOM   1840  H  HD12 . ILE A 1 132 ? 45.525  -2.676  -16.614 1   35.043  ? 138  ILE A HD12 1 c 
ATOM   1841  H  HD13 . ILE A 1 132 ? 46.926  -2.675  -15.859 1   35.018  ? 138  ILE A HD13 1 c 
ATOM   1842  N  N    . ASN A 1 133 ? 46.303  -0.484  -10.686 1   30.986  ? 139  ASN A N    1 ? 
ATOM   1843  C  CA   . ASN A 1 133 ? 47.097  -0.082  -9.555  1   30.901  ? 139  ASN A CA   1 ? 
ATOM   1844  C  C    . ASN A 1 133 ? 46.358  -0.405  -8.259  1   30.68   ? 139  ASN A C    1 ? 
ATOM   1845  O  O    . ASN A 1 133 ? 46.967  -0.826  -7.28   1   32.475  ? 139  ASN A O    1 ? 
ATOM   1846  C  CB   . ASN A 1 133 ? 47.464  1.393   -9.617  1   32.361  ? 139  ASN A CB   1 ? 
ATOM   1847  C  CG   . ASN A 1 133 ? 48.547  1.725   -10.612 1   33.144  ? 139  ASN A CG   1 ? 
ATOM   1848  O  OD1  . ASN A 1 133 ? 49.373  0.883   -10.969 1   33.811  ? 139  ASN A OD1  1 ? 
ATOM   1849  N  ND2  . ASN A 1 133 ? 48.619  2.987   -10.99  1   30.4    ? 139  ASN A ND2  1 ? 
ATOM   1850  H  H    . ASN A 1 133 ? 46.049  0.149   -11.294 1   30.912  ? 139  ASN A H    1 c 
ATOM   1851  H  HA   . ASN A 1 133 ? 47.934  -0.598  -9.57   1   31.165  ? 139  ASN A HA   1 c 
ATOM   1852  H  HB2  . ASN A 1 133 ? 46.663  1.906   -9.843  1   32.171  ? 139  ASN A HB2  1 c 
ATOM   1853  H  HB3  . ASN A 1 133 ? 47.758  1.68    -8.729  1   32.186  ? 139  ASN A HB3  1 c 
ATOM   1854  H  HD21 . ASN A 1 133 ? 49.194  3.226   -11.622 1   31.242  ? 139  ASN A HD21 1 c 
ATOM   1855  H  HD22 . ASN A 1 133 ? 48.096  3.597   -10.614 1   31.24   ? 139  ASN A HD22 1 c 
ATOM   1856  N  N    . GLY A 1 134 ? 45.049  -0.189  -8.242  1   33.975  ? 140  GLY A N    1 ? 
ATOM   1857  C  CA   . GLY A 1 134 ? 44.251  -0.373  -7.031  1   35.611  ? 140  GLY A CA   1 ? 
ATOM   1858  C  C    . GLY A 1 134 ? 44.078  -1.853  -6.718  1   31.072  ? 140  GLY A C    1 ? 
ATOM   1859  O  O    . GLY A 1 134 ? 44.184  -2.293  -5.577  1   29.488  ? 140  GLY A O    1 ? 
ATOM   1860  H  H    . GLY A 1 134 ? 44.629  0.093   -9.003  1   33.453  ? 140  GLY A H    1 c 
ATOM   1861  H  HA2  . GLY A 1 134 ? 44.697  0.077   -6.275  1   34.132  ? 140  GLY A HA2  1 c 
ATOM   1862  H  HA3  . GLY A 1 134 ? 43.367  0.044   -7.158  1   34.155  ? 140  GLY A HA3  1 c 
ATOM   1863  N  N    . ALA A 1 135 ? 43.903  -2.629  -7.77   1   33.037  ? 141  ALA A N    1 ? 
ATOM   1864  C  CA   . ALA A 1 135 ? 43.767  -4.055  -7.612  1   34.033  ? 141  ALA A CA   1 ? 
ATOM   1865  C  C    . ALA A 1 135 ? 45.106  -4.619  -7.134  1   42.152  ? 141  ALA A C    1 ? 
ATOM   1866  O  O    . ALA A 1 135 ? 45.143  -5.514  -6.28   1   35.043  ? 141  ALA A O    1 ? 
ATOM   1867  C  CB   . ALA A 1 135 ? 43.343  -4.657  -8.91   1   37.855  ? 141  ALA A CB   1 ? 
ATOM   1868  H  H    . ALA A 1 135 ? 43.857  -2.267  -8.608  1   32.866  ? 141  ALA A H    1 c 
ATOM   1869  H  HA   . ALA A 1 135 ? 43.076  -4.237  -6.917  1   35.81   ? 141  ALA A HA   1 c 
ATOM   1870  H  HB1  . ALA A 1 135 ? 42.475  -4.304  -9.167  1   36.654  ? 141  ALA A HB1  1 c 
ATOM   1871  H  HB2  . ALA A 1 135 ? 43.994  -4.441  -9.599  1   36.633  ? 141  ALA A HB2  1 c 
ATOM   1872  H  HB3  . ALA A 1 135 ? 43.282  -5.623  -8.818  1   36.638  ? 141  ALA A HB3  1 c 
ATOM   1873  N  N    . PHE A 1 136 ? 46.208  -4.047  -7.655  1   38.622  ? 142  PHE A N    1 ? 
ATOM   1874  C  CA   . PHE A 1 136 ? 47.53   -4.625  -7.449  1   35.262  ? 142  PHE A CA   1 ? 
ATOM   1875  C  C    . PHE A 1 136 ? 47.922  -4.346  -5.998  1   36.227  ? 142  PHE A C    1 ? 
ATOM   1876  O  O    . PHE A 1 136 ? 48.247  -5.257  -5.223  1   34.01   ? 142  PHE A O    1 ? 
ATOM   1877  C  CB   . PHE A 1 136 ? 48.545  -4.063  -8.46   1   29.843  ? 142  PHE A CB   1 ? 
ATOM   1878  C  CG   . PHE A 1 136 ? 49.823  -4.882  -8.566  1   34.252  ? 142  PHE A CG   1 ? 
ATOM   1879  C  CD1  . PHE A 1 136 ? 49.897  -6.007  -9.378  1   38.222  ? 142  PHE A CD1  1 ? 
ATOM   1880  C  CD2  . PHE A 1 136 ? 50.936  -4.558  -7.81   1   35.636  ? 142  PHE A CD2  1 ? 
ATOM   1881  C  CE1  . PHE A 1 136 ? 51.062  -6.766  -9.446  1   39.275  ? 142  PHE A CE1  1 ? 
ATOM   1882  C  CE2  . PHE A 1 136 ? 52.097  -5.301  -7.895  1   36.061  ? 142  PHE A CE2  1 ? 
ATOM   1883  C  CZ   . PHE A 1 136 ? 52.162  -6.4    -8.702  1   39.192  ? 142  PHE A CZ   1 ? 
ATOM   1884  H  H    . PHE A 1 136 ? 46.132  -3.289  -8.159  1   38.406  ? 142  PHE A H    1 c 
ATOM   1885  H  HA   . PHE A 1 136 ? 47.468  -5.609  -7.578  1   35.026  ? 142  PHE A HA   1 c 
ATOM   1886  H  HB2  . PHE A 1 136 ? 48.118  -4.028  -9.344  1   31.957  ? 142  PHE A HB2  1 c 
ATOM   1887  H  HB3  . PHE A 1 136 ? 48.775  -3.144  -8.198  1   31.982  ? 142  PHE A HB3  1 c 
ATOM   1888  H  HD1  . PHE A 1 136 ? 49.145  -6.259  -9.89   1   37.445  ? 142  PHE A HD1  1 c 
ATOM   1889  H  HD2  . PHE A 1 136 ? 50.91   -3.798  -7.251  1   35.437  ? 142  PHE A HD2  1 c 
ATOM   1890  H  HE1  . PHE A 1 136 ? 51.102  -7.519  -10.013 1   38.915  ? 142  PHE A HE1  1 c 
ATOM   1891  H  HE2  . PHE A 1 136 ? 52.848  -5.054  -7.379  1   36.673  ? 142  PHE A HE2  1 c 
ATOM   1892  H  HZ   . PHE A 1 136 ? 52.957  -6.908  -8.749  1   38.39   ? 142  PHE A HZ   1 c 
ATOM   1893  N  N    . TYR A 1 137 ? 47.841  -3.064  -5.644  1   29.441  ? 143  TYR A N    1 ? 
ATOM   1894  C  CA   . TYR A 1 137 ? 48.021  -2.621  -4.274  1   33.74   ? 143  TYR A CA   1 ? 
ATOM   1895  C  C    . TYR A 1 137 ? 47.145  -3.466  -3.328  1   31.987  ? 143  TYR A C    1 ? 
ATOM   1896  O  O    . TYR A 1 137 ? 47.629  -3.926  -2.295  1   38.717  ? 143  TYR A O    1 ? 
ATOM   1897  C  CB   . TYR A 1 137 ? 47.719  -1.111  -4.212  1   33.839  ? 143  TYR A CB   1 ? 
ATOM   1898  C  CG   . TYR A 1 137 ? 47.494  -0.718  -2.763  1   36.305  ? 143  TYR A CG   1 ? 
ATOM   1899  C  CD1  . TYR A 1 137 ? 48.551  -0.606  -1.881  1   36.775  ? 143  TYR A CD1  1 ? 
ATOM   1900  C  CD2  . TYR A 1 137 ? 46.222  -0.564  -2.251  1   33.483  ? 143  TYR A CD2  1 ? 
ATOM   1901  C  CE1  . TYR A 1 137 ? 48.343  -0.331  -0.537  1   37.668  ? 143  TYR A CE1  1 ? 
ATOM   1902  C  CE2  . TYR A 1 137 ? 46.003  -0.334  -0.904  1   34.645  ? 143  TYR A CE2  1 ? 
ATOM   1903  C  CZ   . TYR A 1 137 ? 47.066  -0.209  -0.043  1   37.585  ? 143  TYR A CZ   1 ? 
ATOM   1904  O  OH   . TYR A 1 137 ? 46.835  0.024   1.287   1   42.615  ? 143  TYR A OH   1 ? 
ATOM   1905  H  H    . TYR A 1 137 ? 47.673  -2.436  -6.287  1   31.983  ? 143  TYR A H    1 c 
ATOM   1906  H  HA   . TYR A 1 137 ? 48.973  -2.76   -4.026  1   32.55   ? 143  TYR A HA   1 c 
ATOM   1907  H  HB2  . TYR A 1 137 ? 48.481  -0.61   -4.579  1   34.357  ? 143  TYR A HB2  1 c 
ATOM   1908  H  HB3  . TYR A 1 137 ? 46.91   -0.918  -4.735  1   34.335  ? 143  TYR A HB3  1 c 
ATOM   1909  H  HD1  . TYR A 1 137 ? 49.433  -0.719  -2.198  1   36.838  ? 143  TYR A HD1  1 c 
ATOM   1910  H  HD2  . TYR A 1 137 ? 45.479  -0.686  -2.821  1   34.456  ? 143  TYR A HD2  1 c 
ATOM   1911  H  HE1  . TYR A 1 137 ? 49.079  -0.265  0.048   1   37.417  ? 143  TYR A HE1  1 c 
ATOM   1912  H  HE2  . TYR A 1 137 ? 45.124  -0.234  -0.581  1   35.101  ? 143  TYR A HE2  1 c 
ATOM   1913  H  HH   . TYR A 1 137 ? 46.797  0.849   1.437   0   41.6    ? 143  TYR A HH   1 c 
ATOM   1914  N  N    . SER A 1 138 ? 45.86   -3.65   -3.673  1   30.508  ? 144  SER A N    1 ? 
ATOM   1915  C  CA   . SER A 1 138 ? 44.902  -4.391  -2.85   1   31.605  ? 144  SER A CA   1 ? 
ATOM   1916  C  C    . SER A 1 138 ? 45.395  -5.808  -2.607  1   33.769  ? 144  SER A C    1 ? 
ATOM   1917  O  O    . SER A 1 138 ? 45.094  -6.347  -1.552  1   29.988  ? 144  SER A O    1 ? 
ATOM   1918  C  CB   . SER A 1 138 ? 43.488  -4.391  -3.427  1   34.456  ? 144  SER A CB   1 ? 
ATOM   1919  O  OG   . SER A 1 138 ? 42.919  -3.07   -3.354  1   36.811  ? 144  SER A OG   1 ? 
ATOM   1920  H  H    . SER A 1 138 ? 45.565  -3.292  -4.46   1   31.127  ? 144  SER A H    1 c 
ATOM   1921  H  HA   . SER A 1 138 ? 44.863  -3.938  -1.969  1   32.271  ? 144  SER A HA   1 c 
ATOM   1922  H  HB2  . SER A 1 138 ? 43.517  -4.684  -4.357  1   34.338  ? 144  SER A HB2  1 c 
ATOM   1923  H  HB3  . SER A 1 138 ? 42.931  -5.015  -2.924  1   34.333  ? 144  SER A HB3  1 c 
ATOM   1924  H  HG   . SER A 1 138 ? 42.11   -3.127  -3.664  0   36.47   ? 144  SER A HG   1 c 
ATOM   1925  N  N    . CYS A 1 139 ? 46.134  -6.409  -3.559  1   35.483  ? 145  CYS A N    1 ? 
ATOM   1926  C  CA   . CYS A 1 139 ? 46.616  -7.77   -3.369  1   32.724  ? 145  CYS A CA   1 ? 
ATOM   1927  C  C    . CYS A 1 139 ? 47.862  -7.779  -2.476  1   35.933  ? 145  CYS A C    1 ? 
ATOM   1928  O  O    . CYS A 1 139 ? 48.177  -8.816  -1.887  1   35.349  ? 145  CYS A O    1 ? 
ATOM   1929  C  CB   . CYS A 1 139 ? 46.888  -8.481  -4.701  1   35.306  ? 145  CYS A CB   1 ? 
ATOM   1930  S  SG   . CYS A 1 139 ? 45.458  -8.687  -5.816  1   34.237  ? 145  CYS A SG   1 ? 
ATOM   1931  H  H    . CYS A 1 139 ? 46.325  -5.973  -4.339  1   34.388  ? 145  CYS A H    1 c 
ATOM   1932  H  HA   . CYS A 1 139 ? 45.903  -8.28   -2.906  1   34.264  ? 145  CYS A HA   1 c 
ATOM   1933  H  HB2  . CYS A 1 139 ? 47.579  -7.978  -5.187  1   34.472  ? 145  CYS A HB2  1 c 
ATOM   1934  H  HB3  . CYS A 1 139 ? 47.253  -9.373  -4.51   1   34.472  ? 145  CYS A HB3  1 c 
ATOM   1935  H  HG   . CYS A 1 139 ? 46.048  -9.253  -6.714  0   34.07   ? 145  CYS A HG   1 c 
ATOM   1936  N  N    . GLU A 1 140 ? 48.632  -6.663  -2.446  1   29.499  ? 146  GLU A N    1 ? 
ATOM   1937  C  CA   . GLU A 1 140 ? 49.79   -6.505  -1.57   1   30.904  ? 146  GLU A CA   1 ? 
ATOM   1938  C  C    . GLU A 1 140 ? 49.411  -6.26   -0.095  1   33.142  ? 146  GLU A C    1 ? 
ATOM   1939  O  O    . GLU A 1 140 ? 50.095  -6.739  0.807   1   32.397  ? 146  GLU A O    1 ? 
ATOM   1940  C  CB   . GLU A 1 140 ? 50.68   -5.365  -2.073  1   31.463  ? 146  GLU A CB   1 ? 
ATOM   1941  C  CG   . GLU A 1 140 ? 51.328  -5.675  -3.417  1   34.092  ? 146  GLU A CG   1 ? 
ATOM   1942  C  CD   . GLU A 1 140 ? 52.215  -4.556  -3.896  1   36.653  ? 146  GLU A CD   1 ? 
ATOM   1943  O  OE1  . GLU A 1 140 ? 53.245  -4.884  -4.515  1   35.226  ? 146  GLU A OE1  1 ? 
ATOM   1944  O  OE2  . GLU A 1 140 ? 51.882  -3.388  -3.614  1   32.999  ? 146  GLU A OE2  1 ? 
ATOM   1945  H  H    . GLU A 1 140 ? 48.425  -5.975  -3.011  1   31.297  ? 146  GLU A H    1 c 
ATOM   1946  H  HA   . GLU A 1 140 ? 50.32   -7.341  -1.614  1   31.162  ? 146  GLU A HA   1 c 
ATOM   1947  H  HB2  . GLU A 1 140 ? 50.139  -4.552  -2.151  1   31.949  ? 146  GLU A HB2  1 c 
ATOM   1948  H  HB3  . GLU A 1 140 ? 51.383  -5.194  -1.411  1   31.929  ? 146  GLU A HB3  1 c 
ATOM   1949  H  HG2  . GLU A 1 140 ? 51.863  -6.492  -3.336  1   34.048  ? 146  GLU A HG2  1 c 
ATOM   1950  H  HG3  . GLU A 1 140 ? 50.629  -5.833  -4.087  1   34.021  ? 146  GLU A HG3  1 c 
ATOM   1951  N  N    . MET A 1 141 ? 48.34   -5.492  0.162   1   32.078  ? 147  MET A N    1 ? 
ATOM   1952  C  CA   . MET A 1 141 ? 47.85   -5.275  1.516   1   33.403  ? 147  MET A CA   1 ? 
ATOM   1953  C  C    . MET A 1 141 ? 47.735  -6.616  2.205   1   35.092  ? 147  MET A C    1 ? 
ATOM   1954  O  O    . MET A 1 141 ? 47.338  -7.585  1.563   1   38.973  ? 147  MET A O    1 ? 
ATOM   1955  C  CB   . MET A 1 141 ? 46.403  -4.767  1.557   1   38.154  ? 147  MET A CB   1 ? 
ATOM   1956  C  CG   . MET A 1 141 ? 46.237  -3.357  1.143   1   36.388  ? 147  MET A CG   1 ? 
ATOM   1957  S  SD   . MET A 1 141 ? 44.503  -2.864  1.278   1   35.53   ? 147  MET A SD   1 ? 
ATOM   1958  C  CE   . MET A 1 141 ? 44.345  -2.822  3.065   1   35.908  ? 147  MET A CE   1 ? 
ATOM   1959  H  H    . MET A 1 141 ? 47.904  -5.087  -0.532  1   32.625  ? 147  MET A H    1 c 
ATOM   1960  H  HA   . MET A 1 141 ? 48.459  -4.67   2.011   1   34.253  ? 147  MET A HA   1 c 
ATOM   1961  H  HB2  . MET A 1 141 ? 45.858  -5.334  0.971   1   36.606  ? 147  MET A HB2  1 c 
ATOM   1962  H  HB3  . MET A 1 141 ? 46.063  -4.87   2.47    1   36.598  ? 147  MET A HB3  1 c 
ATOM   1963  H  HG2  . MET A 1 141 ? 46.782  -2.778  1.713   1   36.649  ? 147  MET A HG2  1 c 
ATOM   1964  H  HG3  . MET A 1 141 ? 46.532  -3.246  0.218   1   36.649  ? 147  MET A HG3  1 c 
ATOM   1965  H  HE1  . MET A 1 141 ? 43.546  -2.316  3.309   1   35.855  ? 147  MET A HE1  1 c 
ATOM   1966  H  HE2  . MET A 1 141 ? 44.267  -3.733  3.403   1   35.84   ? 147  MET A HE2  1 c 
ATOM   1967  H  HE3  . MET A 1 141 ? 45.134  -2.401  3.452   1   35.996  ? 147  MET A HE3  1 c 
ATOM   1968  N  N    . THR A 1 142 ? 48.089  -6.664  3.497   1   34.55   ? 148  THR A N    1 ? 
ATOM   1969  C  CA   . THR A 1 142 ? 48.122  -7.939  4.18    1   36.451  ? 148  THR A CA   1 ? 
ATOM   1970  C  C    . THR A 1 142 ? 46.704  -8.437  4.37    1   31.673  ? 148  THR A C    1 ? 
ATOM   1971  O  O    . THR A 1 142 ? 46.49   -9.643  4.319   1   30.779  ? 148  THR A O    1 ? 
ATOM   1972  C  CB   . THR A 1 142 ? 48.875  -7.86   5.506   1   41.473  ? 148  THR A CB   1 ? 
ATOM   1973  O  OG1  . THR A 1 142 ? 50.195  -7.376  5.227   1   39.336  ? 148  THR A OG1  1 ? 
ATOM   1974  C  CG2  . THR A 1 142 ? 48.961  -9.226  6.155   1   35.988  ? 148  THR A CG2  1 ? 
ATOM   1975  H  H    . THR A 1 142 ? 48.307  -5.902  3.951   1   35.119  ? 148  THR A H    1 c 
ATOM   1976  H  HA   . THR A 1 142 ? 48.596  -8.578  3.603   1   35.971  ? 148  THR A HA   1 c 
ATOM   1977  H  HB   . THR A 1 142 ? 48.417  -7.233  6.115   1   39.071  ? 148  THR A HB   1 c 
ATOM   1978  H  HG1  . THR A 1 142 ? 50.599  -7.93   4.678   0   39.71   ? 148  THR A HG1  1 c 
ATOM   1979  H  HG21 . THR A 1 142 ? 49.581  -9.192  6.903   1   37.517  ? 148  THR A HG21 1 c 
ATOM   1980  H  HG22 . THR A 1 142 ? 49.276  -9.876  5.504   1   37.516  ? 148  THR A HG22 1 c 
ATOM   1981  H  HG23 . THR A 1 142 ? 48.082  -9.491  6.477   1   37.459  ? 148  THR A HG23 1 c 
ATOM   1982  N  N    . SER A 1 143 ? 45.774  -7.489  4.596   1   36.197  ? 149  SER A N    1 ? 
ATOM   1983  C  CA   . SER A 1 143 ? 44.419  -7.759  5.052   1   33.807  ? 149  SER A CA   1 ? 
ATOM   1984  C  C    . SER A 1 143 ? 43.482  -6.618  4.643   1   31.806  ? 149  SER A C    1 ? 
ATOM   1985  O  O    . SER A 1 143 ? 43.853  -5.448  4.67    1   32.944  ? 149  SER A O    1 ? 
ATOM   1986  C  CB   . SER A 1 143 ? 44.37   -7.935  6.537   1   36.232  ? 149  SER A CB   1 ? 
ATOM   1987  O  OG   . SER A 1 143 ? 43.05   -8.237  6.958   1   33.384  ? 149  SER A OG   1 ? 
ATOM   1988  H  H    . SER A 1 143 ? 46.01   -6.616  4.464   1   34.523  ? 149  SER A H    1 c 
ATOM   1989  H  HA   . SER A 1 143 ? 44.105  -8.594  4.622   1   34.194  ? 149  SER A HA   1 c 
ATOM   1990  H  HB2  . SER A 1 143 ? 44.97   -8.658  6.799   1   35.02   ? 149  SER A HB2  1 c 
ATOM   1991  H  HB3  . SER A 1 143 ? 44.67   -7.113  6.971   1   35.022  ? 149  SER A HB3  1 c 
ATOM   1992  H  HG   . SER A 1 143 ? 43.037  -8.364  7.778   0   34.83   ? 149  SER A HG   1 c 
ATOM   1993  N  N    . TRP A 1 144 ? 42.238  -6.989  4.328   1   26.774  ? 150  TRP A N    1 ? 
ATOM   1994  C  CA   . TRP A 1 144 ? 41.166  -6.043  4.068   1   29.033  ? 150  TRP A CA   1 ? 
ATOM   1995  C  C    . TRP A 1 144 ? 40.302  -5.778  5.314   1   29.898  ? 150  TRP A C    1 ? 
ATOM   1996  O  O    . TRP A 1 144 ? 39.299  -5.054  5.228   1   32.949  ? 150  TRP A O    1 ? 
ATOM   1997  C  CB   . TRP A 1 144 ? 40.329  -6.596  2.904   1   28.222  ? 150  TRP A CB   1 ? 
ATOM   1998  C  CG   . TRP A 1 144 ? 41.07   -6.841  1.615   1   29.17   ? 150  TRP A CG   1 ? 
ATOM   1999  C  CD1  . TRP A 1 144 ? 42.175  -6.177  1.154   1   33.697  ? 150  TRP A CD1  1 ? 
ATOM   2000  C  CD2  . TRP A 1 144 ? 40.684  -7.746  0.555   1   32.948  ? 150  TRP A CD2  1 ? 
ATOM   2001  N  NE1  . TRP A 1 144 ? 42.533  -6.631  -0.086  1   32.478  ? 150  TRP A NE1  1 ? 
ATOM   2002  C  CE2  . TRP A 1 144 ? 41.639  -7.599  -0.477  1   31.621  ? 150  TRP A CE2  1 ? 
ATOM   2003  C  CE3  . TRP A 1 144 ? 39.65   -8.679  0.383   1   29.342  ? 150  TRP A CE3  1 ? 
ATOM   2004  C  CZ2  . TRP A 1 144 ? 41.592  -8.36   -1.639  1   30.725  ? 150  TRP A CZ2  1 ? 
ATOM   2005  C  CZ3  . TRP A 1 144 ? 39.613  -9.428  -0.775  1   32.252  ? 150  TRP A CZ3  1 ? 
ATOM   2006  C  CH2  . TRP A 1 144 ? 40.571  -9.268  -1.776  1   30.688  ? 150  TRP A CH2  1 ? 
ATOM   2007  H  H    . TRP A 1 144 ? 42.047  -7.881  4.275   1   28.491  ? 150  TRP A H    1 c 
ATOM   2008  H  HA   . TRP A 1 144 ? 41.57   -5.182  3.777   1   28.642  ? 150  TRP A HA   1 c 
ATOM   2009  H  HB2  . TRP A 1 144 ? 39.92   -7.439  3.193   1   28.662  ? 150  TRP A HB2  1 c 
ATOM   2010  H  HB3  . TRP A 1 144 ? 39.596  -5.968  2.727   1   28.649  ? 150  TRP A HB3  1 c 
ATOM   2011  H  HD1  . TRP A 1 144 ? 42.645  -5.513  1.632   1   32.283  ? 150  TRP A HD1  1 c 
ATOM   2012  H  HE1  . TRP A 1 144 ? 43.227  -6.364  -0.544  1   32.513  ? 150  TRP A HE1  1 c 
ATOM   2013  H  HE3  . TRP A 1 144 ? 39.008  -8.81   1.06    1   30.801  ? 150  TRP A HE3  1 c 
ATOM   2014  H  HZ2  . TRP A 1 144 ? 42.231  -8.241  -2.321  1   30.934  ? 150  TRP A HZ2  1 c 
ATOM   2015  H  HZ3  . TRP A 1 144 ? 38.922  -10.058 -0.895  1   31.217  ? 150  TRP A HZ3  1 c 
ATOM   2016  H  HH2  . TRP A 1 144 ? 40.509  -9.78   -2.563  1   31.051  ? 150  TRP A HH2  1 c 
ATOM   2017  N  N    . VAL A 1 145 ? 40.688  -6.318  6.481   1   31.774  ? 151  VAL A N    1 ? 
ATOM   2018  C  CA   . VAL A 1 145 ? 39.872  -6.242  7.702   1   31.142  ? 151  VAL A CA   1 ? 
ATOM   2019  C  C    . VAL A 1 145 ? 40.221  -5.016  8.54    1   33.825  ? 151  VAL A C    1 ? 
ATOM   2020  O  O    . VAL A 1 145 ? 41.36   -4.563  8.545   1   36.748  ? 151  VAL A O    1 ? 
ATOM   2021  C  CB   . VAL A 1 145 ? 40.122  -7.548  8.454   1   32.496  ? 151  VAL A CB   1 ? 
ATOM   2022  C  CG1  . VAL A 1 145 ? 39.437  -7.589  9.824   1   34.588  ? 151  VAL A CG1  1 ? 
ATOM   2023  C  CG2  . VAL A 1 145 ? 39.691  -8.723  7.594   1   32.193  ? 151  VAL A CG2  1 ? 
ATOM   2024  H  H    . VAL A 1 145 ? 41.495  -6.743  6.526   1   31.16   ? 151  VAL A H    1 c 
ATOM   2025  H  HA   . VAL A 1 145 ? 38.932  -6.197  7.45    1   32.01   ? 151  VAL A HA   1 c 
ATOM   2026  H  HB   . VAL A 1 145 ? 41.093  -7.619  8.602   1   32.551  ? 151  VAL A HB   1 c 
ATOM   2027  H  HG11 . VAL A 1 145 ? 38.478  -7.493  9.711   1   33.956  ? 151  VAL A HG11 1 c 
ATOM   2028  H  HG12 . VAL A 1 145 ? 39.77   -6.865  10.379  1   33.977  ? 151  VAL A HG12 1 c 
ATOM   2029  H  HG13 . VAL A 1 145 ? 39.628  -8.438  10.256  1   33.963  ? 151  VAL A HG13 1 c 
ATOM   2030  H  HG21 . VAL A 1 145 ? 39.938  -9.553  8.035   1   32.335  ? 151  VAL A HG21 1 c 
ATOM   2031  H  HG22 . VAL A 1 145 ? 40.129  -8.676  6.729   1   32.287  ? 151  VAL A HG22 1 c 
ATOM   2032  H  HG23 . VAL A 1 145 ? 38.727  -8.699  7.471   1   32.31   ? 151  VAL A HG23 1 c 
ATOM   2033  N  N    . LEU A 1 146 ? 39.231  -4.442  9.237   1   36.408  ? 152  LEU A N    1 ? 
ATOM   2034  C  CA   . LEU A 1 146 ? 39.442  -3.216  10      1   32.338  ? 152  LEU A CA   1 ? 
ATOM   2035  C  C    . LEU A 1 146 ? 40.269  -3.57   11.23   1   29.862  ? 152  LEU A C    1 ? 
ATOM   2036  O  O    . LEU A 1 146 ? 40.157  -4.688  11.74   1   30.307  ? 152  LEU A O    1 ? 
ATOM   2037  C  CB   . LEU A 1 146 ? 38.151  -2.501  10.392  1   34.566  ? 152  LEU A CB   1 ? 
ATOM   2038  C  CG   . LEU A 1 146 ? 37.162  -2.165  9.261   1   37.849  ? 152  LEU A CG   1 ? 
ATOM   2039  C  CD1  . LEU A 1 146 ? 35.89   -1.525  9.821   1   35.313  ? 152  LEU A CD1  1 ? 
ATOM   2040  C  CD2  . LEU A 1 146 ? 37.707  -1.245  8.184   1   38.189  ? 152  LEU A CD2  1 ? 
ATOM   2041  H  H    . LEU A 1 146 ? 38.401  -4.825  9.238   1   34.787  ? 152  LEU A H    1 c 
ATOM   2042  H  HA   . LEU A 1 146 ? 39.978  -2.603  9.438   1   32.943  ? 152  LEU A HA   1 c 
ATOM   2043  H  HB2  . LEU A 1 146 ? 37.682  -3.061  11.054  1   34.758  ? 152  LEU A HB2  1 c 
ATOM   2044  H  HB3  . LEU A 1 146 ? 38.394  -1.662  10.847  1   34.75   ? 152  LEU A HB3  1 c 
ATOM   2045  H  HG   . LEU A 1 146 ? 36.902  -3.015  8.823   1   36.754  ? 152  LEU A HG   1 c 
ATOM   2046  H  HD11 . LEU A 1 146 ? 35.472  -2.132  10.449  1   36.156  ? 152  LEU A HD11 1 c 
ATOM   2047  H  HD12 . LEU A 1 146 ? 35.273  -1.338  9.093   1   36.091  ? 152  LEU A HD12 1 c 
ATOM   2048  H  HD13 . LEU A 1 146 ? 36.115  -0.696  10.275  1   36.072  ? 152  LEU A HD13 1 c 
ATOM   2049  H  HD21 . LEU A 1 146 ? 38.477  -1.661  7.761   1   38.056  ? 152  LEU A HD21 1 c 
ATOM   2050  H  HD22 . LEU A 1 146 ? 37.976  -0.4    8.584   1   38.078  ? 152  LEU A HD22 1 c 
ATOM   2051  H  HD23 . LEU A 1 146 ? 37.02   -1.082  7.517   1   38.068  ? 152  LEU A HD23 1 c 
ATOM   2052  N  N    . SER A 1 147 ? 41.145  -2.643  11.636  1   23.689  ? 153  SER A N    1 ? 
ATOM   2053  C  CA   . SER A 1 147 ? 42.024  -2.831  12.786  1   31.041  ? 153  SER A CA   1 ? 
ATOM   2054  C  C    . SER A 1 147 ? 41.264  -3.28   14.029  1   31.784  ? 153  SER A C    1 ? 
ATOM   2055  O  O    . SER A 1 147 ? 41.755  -4.159  14.746  1   40.024  ? 153  SER A O    1 ? 
ATOM   2056  C  CB   . SER A 1 147 ? 42.852  -1.6    13.112  1   25.972  ? 153  SER A CB   1 ? 
ATOM   2057  O  OG   . SER A 1 147 ? 42.04   -0.436  13.234  1   33.009  ? 153  SER A OG   1 ? 
ATOM   2058  H  H    . SER A 1 147 ? 41.195  -1.854  11.176  1   26.686  ? 153  SER A H    1 c 
ATOM   2059  H  HA   . SER A 1 147 ? 42.654  -3.557  12.552  1   28.715  ? 153  SER A HA   1 c 
ATOM   2060  H  HB2  . SER A 1 147 ? 43.333  -1.747  13.949  1   28.655  ? 153  SER A HB2  1 c 
ATOM   2061  H  HB3  . SER A 1 147 ? 43.512  -1.461  12.407  1   28.689  ? 153  SER A HB3  1 c 
ATOM   2062  H  HG   . SER A 1 147 ? 42.531  0.222   13.428  0   33.39   ? 153  SER A HG   1 c 
ATOM   2063  N  N    . ALA A 1 148 ? 40.095  -2.675  14.29   1   33.524  ? 154  ALA A N    1 ? 
ATOM   2064  C  CA   . ALA A 1 148 ? 39.283  -3.057  15.448  1   36.699  ? 154  ALA A CA   1 ? 
ATOM   2065  C  C    . ALA A 1 148 ? 38.694  -4.468  15.332  1   38.77   ? 154  ALA A C    1 ? 
ATOM   2066  O  O    . ALA A 1 148 ? 38.276  -5.033  16.346  1   36.937  ? 154  ALA A O    1 ? 
ATOM   2067  C  CB   . ALA A 1 148 ? 38.174  -2.044  15.668  1   41.355  ? 154  ALA A CB   1 ? 
ATOM   2068  H  H    . ALA A 1 148 ? 39.796  -2.01   13.739  1   33.724  ? 154  ALA A H    1 c 
ATOM   2069  H  HA   . ALA A 1 148 ? 39.878  -3.046  16.246  1   37.245  ? 154  ALA A HA   1 c 
ATOM   2070  H  HB1  . ALA A 1 148 ? 38.56   -1.165  15.822  1   39.921  ? 154  ALA A HB1  1 c 
ATOM   2071  H  HB2  . ALA A 1 148 ? 37.602  -2.011  14.883  1   39.921  ? 154  ALA A HB2  1 c 
ATOM   2072  H  HB3  . ALA A 1 148 ? 37.644  -2.302  16.441  1   39.921  ? 154  ALA A HB3  1 c 
ATOM   2073  N  N    . HIS A 1 149 ? 38.696  -5.063  14.13   1   35.672  ? 155  HIS A N    1 ? 
ATOM   2074  C  CA   . HIS A 1 149 ? 38.038  -6.354  13.891  1   38.258  ? 155  HIS A CA   1 ? 
ATOM   2075  C  C    . HIS A 1 149 ? 39.075  -7.474  13.763  1   36.754  ? 155  HIS A C    1 ? 
ATOM   2076  O  O    . HIS A 1 149 ? 38.743  -8.682  13.781  1   36.881  ? 155  HIS A O    1 ? 
ATOM   2077  C  CB   . HIS A 1 149 ? 37.094  -6.289  12.674  1   38.173  ? 155  HIS A CB   1 ? 
ATOM   2078  C  CG   . HIS A 1 149 ? 35.974  -5.315  12.82   1   41.804  ? 155  HIS A CG   1 ? 
ATOM   2079  N  ND1  . HIS A 1 149 ? 35.477  -4.548  11.785  1   43.467  ? 155  HIS A ND1  1 ? 
ATOM   2080  C  CD2  . HIS A 1 149 ? 35.292  -4.941  13.909  1   42.082  ? 155  HIS A CD2  1 ? 
ATOM   2081  C  CE1  . HIS A 1 149 ? 34.548  -3.724  12.243  1   41.175  ? 155  HIS A CE1  1 ? 
ATOM   2082  N  NE2  . HIS A 1 149 ? 34.436  -3.93   13.529  1   43.767  ? 155  HIS A NE2  1 ? 
ATOM   2083  H  H    . HIS A 1 149 ? 39.095  -4.644  13.424  1   36.857  ? 155  HIS A H    1 c 
ATOM   2084  H  HA   . HIS A 1 149 ? 37.479  -6.552  14.682  1   37.471  ? 155  HIS A HA   1 c 
ATOM   2085  H  HB2  . HIS A 1 149 ? 37.622  -6.049  11.881  1   39.01   ? 155  HIS A HB2  1 c 
ATOM   2086  H  HB3  . HIS A 1 149 ? 36.719  -7.184  12.52   1   39.01   ? 155  HIS A HB3  1 c 
ATOM   2087  H  HD1  . HIS A 1 149 ? 35.72   -4.612  10.924  0   43.61   ? 155  HIS A HD1  1 c 
ATOM   2088  H  HD2  . HIS A 1 149 ? 35.415  -5.255  14.783  1   42.366  ? 155  HIS A HD2  1 c 
ATOM   2089  H  HE1  . HIS A 1 149 ? 34.042  -3.116  11.733  1   42.222  ? 155  HIS A HE1  1 c 
ATOM   2090  H  HE2  . HIS A 1 149 ? 33.893  -3.485  14.046  0   42.87   ? 155  HIS A HE2  1 c 
ATOM   2091  N  N    . LEU A 1 150 ? 40.358  -7.086  13.754  1   36.677  ? 156  LEU A N    1 ? 
ATOM   2092  C  CA   . LEU A 1 150 ? 41.43   -8.065  13.572  1   38.868  ? 156  LEU A CA   1 ? 
ATOM   2093  C  C    . LEU A 1 150 ? 41.725  -8.823  14.868  1   30.583  ? 156  LEU A C    1 ? 
ATOM   2094  O  O    . LEU A 1 150 ? 42.362  -9.87   14.832  1   33.551  ? 156  LEU A O    1 ? 
ATOM   2095  C  CB   . LEU A 1 150 ? 42.675  -7.373  13.006  1   42.048  ? 156  LEU A CB   1 ? 
ATOM   2096  C  CG   . LEU A 1 150 ? 42.746  -7.231  11.48   1   37.049  ? 156  LEU A CG   1 ? 
ATOM   2097  C  CD1  . LEU A 1 150 ? 43.791  -6.169  11.094  1   33.732  ? 156  LEU A CD1  1 ? 
ATOM   2098  C  CD2  . LEU A 1 150 ? 43.119  -8.573  10.822  1   40.249  ? 156  LEU A CD2  1 ? 
ATOM   2099  H  H    . LEU A 1 150 ? 40.575  -6.207  13.87   1   37.218  ? 156  LEU A H    1 c 
ATOM   2100  H  HA   . LEU A 1 150 ? 41.116  -8.729  12.907  1   37.311  ? 156  LEU A HA   1 c 
ATOM   2101  H  HB2  . LEU A 1 150 ? 42.735  -6.475  13.405  1   40      ? 156  LEU A HB2  1 c 
ATOM   2102  H  HB3  . LEU A 1 150 ? 43.467  -7.876  13.305  1   40.041  ? 156  LEU A HB3  1 c 
ATOM   2103  H  HG   . LEU A 1 150 ? 41.859  -6.944  11.145  1   37.802  ? 156  LEU A HG   1 c 
ATOM   2104  H  HD11 . LEU A 1 150 ? 43.557  -5.32   11.503  1   34.662  ? 156  LEU A HD11 1 c 
ATOM   2105  H  HD12 . LEU A 1 150 ? 43.809  -6.068  10.127  1   34.674  ? 156  LEU A HD12 1 c 
ATOM   2106  H  HD13 . LEU A 1 150 ? 44.668  -6.448  11.406  1   34.702  ? 156  LEU A HD13 1 c 
ATOM   2107  H  HD21 . LEU A 1 150 ? 42.419  -9.225  10.994  1   39.274  ? 156  LEU A HD21 1 c 
ATOM   2108  H  HD22 . LEU A 1 150 ? 43.958  -8.895  11.193  1   39.287  ? 156  LEU A HD22 1 c 
ATOM   2109  H  HD23 . LEU A 1 150 ? 43.216  -8.45   9.863   1   39.285  ? 156  LEU A HD23 1 c 
ATOM   2110  N  N    . VAL A 1 151 ? 41.202  -8.34   15.992  1   32.774  ? 157  VAL A N    1 ? 
ATOM   2111  C  CA   . VAL A 1 151 ? 41.369  -8.985  17.284  1   41.558  ? 157  VAL A CA   1 ? 
ATOM   2112  C  C    . VAL A 1 151 ? 40.55   -10.266 17.381  1   47.694  ? 157  VAL A C    1 ? 
ATOM   2113  O  O    . VAL A 1 151 ? 40.638  -10.945 18.404  1   54.834  ? 157  VAL A O    1 ? 
ATOM   2114  C  CB   . VAL A 1 151 ? 41.058  -8.056  18.472  1   46.011  ? 157  VAL A CB   1 ? 
ATOM   2115  C  CG1  . VAL A 1 151 ? 41.983  -6.843  18.472  1   45.958  ? 157  VAL A CG1  1 ? 
ATOM   2116  C  CG2  . VAL A 1 151 ? 39.599  -7.632  18.531  1   48.841  ? 157  VAL A CG2  1 ? 
ATOM   2117  H  H    . VAL A 1 151 ? 40.732  -7.557  15.958  1   34.447  ? 157  VAL A H    1 c 
ATOM   2118  H  HA   . VAL A 1 151 ? 42.31   -9.238  17.357  1   41.367  ? 157  VAL A HA   1 c 
ATOM   2119  H  HB   . VAL A 1 151 ? 41.248  -8.567  19.293  1   45.694  ? 157  VAL A HB   1 c 
ATOM   2120  H  HG11 . VAL A 1 151 ? 41.846  -6.329  17.658  1   45.798  ? 157  VAL A HG11 1 c 
ATOM   2121  H  HG12 . VAL A 1 151 ? 42.908  -7.14   18.515  1   45.932  ? 157  VAL A HG12 1 c 
ATOM   2122  H  HG13 . VAL A 1 151 ? 41.787  -6.285  19.243  1   45.932  ? 157  VAL A HG13 1 c 
ATOM   2123  H  HG21 . VAL A 1 151 ? 39.475  -7      19.258  1   47.958  ? 157  VAL A HG21 1 c 
ATOM   2124  H  HG22 . VAL A 1 151 ? 39.038  -8.411  18.682  1   47.958  ? 157  VAL A HG22 1 c 
ATOM   2125  H  HG23 . VAL A 1 151 ? 39.347  -7.211  17.692  1   47.865  ? 157  VAL A HG23 1 c 
ATOM   2126  N  N    . ARG A 1 152 ? 39.838  -10.637 16.308  1   43.863  ? 158  ARG A N    1 ? 
ATOM   2127  C  CA   . ARG A 1 152 ? 39.178  -11.94  16.228  1   47.389  ? 158  ARG A CA   1 ? 
ATOM   2128  C  C    . ARG A 1 152 ? 40.059  -12.968 15.53   1   42.194  ? 158  ARG A C    1 ? 
ATOM   2129  O  O    . ARG A 1 152 ? 39.572  -14.041 15.19   1   45.641  ? 158  ARG A O    1 ? 
ATOM   2130  C  CB   . ARG A 1 152 ? 37.846  -11.933 15.452  1   45.293  ? 158  ARG A CB   1 ? 
ATOM   2131  C  CG   . ARG A 1 152 ? 36.792  -10.926 15.905  1   53.096  ? 158  ARG A CG   1 ? 
ATOM   2132  C  CD   . ARG A 1 152 ? 35.91   -11.193 17.156  1   59.261  ? 158  ARG A CD   1 ? 
ATOM   2133  N  NE   . ARG A 1 152 ? 34.686  -10.393 16.961  1   72.883  ? 158  ARG A NE   1 ? 
ATOM   2134  C  CZ   . ARG A 1 152 ? 34.584  -9.048  16.978  1   81.598  ? 158  ARG A CZ   1 ? 
ATOM   2135  N  NH1  . ARG A 1 152 ? 33.934  -8.415  16.017  1   78.173  ? 158  ARG A NH1  1 ? 
ATOM   2136  N  NH2  . ARG A 1 152 ? 35.299  -8.307  17.805  1   90.594  ? 158  ARG A NH2  1 ? 
ATOM   2137  H  H    . ARG A 1 152 ? 39.736  -10.056 15.611  1   45.25   ? 158  ARG A H    1 c 
ATOM   2138  H  HA   . ARG A 1 152 ? 38.998  -12.256 17.149  1   45.387  ? 158  ARG A HA   1 c 
ATOM   2139  H  HB2  . ARG A 1 152 ? 38.045  -11.765 14.506  1   47.418  ? 158  ARG A HB2  1 c 
ATOM   2140  H  HB3  . ARG A 1 152 ? 37.454  -12.83  15.511  1   47.413  ? 158  ARG A HB3  1 c 
ATOM   2141  H  HG2  . ARG A 1 152 ? 37.248  -10.068 16.045  1   52.436  ? 158  ARG A HG2  1 c 
ATOM   2142  H  HG3  . ARG A 1 152 ? 36.189  -10.773 15.145  1   52.565  ? 158  ARG A HG3  1 c 
ATOM   2143  H  HD2  . ARG A 1 152 ? 35.68   -12.142 17.228  1   60.763  ? 158  ARG A HD2  1 c 
ATOM   2144  H  HD3  . ARG A 1 152 ? 36.367  -10.909 17.974  1   60.763  ? 158  ARG A HD3  1 c 
ATOM   2145  H  HE   . ARG A 1 152 ? 33.948  -10.828 16.837  1   70.968  ? 158  ARG A HE   1 c 
ATOM   2146  H  HH11 . ARG A 1 152 ? 34.13   -8.583  15.17   1   79.013  ? 158  ARG A HH11 1 c 
ATOM   2147  H  HH12 . ARG A 1 152 ? 33.308  -7.825  16.223  1   79.165  ? 158  ARG A HH12 1 c 
ATOM   2148  H  HH21 . ARG A 1 152 ? 35.621  -8.664  18.546  1   87.705  ? 158  ARG A HH21 1 c 
ATOM   2149  H  HH22 . ARG A 1 152 ? 35.452  -7.456  17.615  1   87.645  ? 158  ARG A HH22 1 c 
ATOM   2150  N  N    . GLN A 1 153 ? 41.311  -12.625 15.211  1   40.586  ? 159  GLN A N    1 ? 
ATOM   2151  C  CA   . GLN A 1 153 ? 42.274  -13.644 14.803  1   45.569  ? 159  GLN A CA   1 ? 
ATOM   2152  C  C    . GLN A 1 153 ? 42.553  -14.55  16.007  1   36.707  ? 159  GLN A C    1 ? 
ATOM   2153  O  O    . GLN A 1 153 ? 42.282  -14.13  17.141  1   40.082  ? 159  GLN A O    1 ? 
ATOM   2154  C  CB   . GLN A 1 153 ? 43.581  -13.016 14.305  1   43.31   ? 159  GLN A CB   1 ? 
ATOM   2155  C  CG   . GLN A 1 153 ? 43.418  -12.094 13.107  1   38.965  ? 159  GLN A CG   1 ? 
ATOM   2156  C  CD   . GLN A 1 153 ? 44.659  -11.29  12.771  1   39.225  ? 159  GLN A CD   1 ? 
ATOM   2157  O  OE1  . GLN A 1 153 ? 45.142  -11.313 11.634  1   34.295  ? 159  GLN A OE1  1 ? 
ATOM   2158  N  NE2  . GLN A 1 153 ? 45.151  -10.519 13.725  1   39.093  ? 159  GLN A NE2  1 ? 
ATOM   2159  H  H    . GLN A 1 153 ? 41.574  -11.751 15.243  1   42.089  ? 159  GLN A H    1 c 
ATOM   2160  H  HA   . GLN A 1 153 ? 41.874  -14.185 14.075  1   42.487  ? 159  GLN A HA   1 c 
ATOM   2161  H  HB2  . GLN A 1 153 ? 43.981  -12.508 15.042  1   42.724  ? 159  GLN A HB2  1 c 
ATOM   2162  H  HB3  . GLN A 1 153 ? 44.204  -13.734 14.069  1   42.77   ? 159  GLN A HB3  1 c 
ATOM   2163  H  HG2  . GLN A 1 153 ? 43.18   -12.633 12.322  1   39.932  ? 159  GLN A HG2  1 c 
ATOM   2164  H  HG3  . GLN A 1 153 ? 42.678  -11.476 13.271  1   39.934  ? 159  GLN A HG3  1 c 
ATOM   2165  H  HE21 . GLN A 1 153 ? 45.982  -10.213 13.662  1   39.101  ? 159  GLN A HE21 1 c 
ATOM   2166  H  HE22 . GLN A 1 153 ? 44.651  -10.306 14.426  1   39.151  ? 159  GLN A HE22 1 c 
ATOM   2167  N  N    . SER A 1 154 ? 43.078  -15.76  15.73   1   37.227  ? 160  SER A N    1 ? 
ATOM   2168  C  CA   . SER A 1 154 ? 43.582  -16.728 16.717  1   45.884  ? 160  SER A CA   1 ? 
ATOM   2169  C  C    . SER A 1 154 ? 44.313  -16.068 17.873  1   47.779  ? 160  SER A C    1 ? 
ATOM   2170  O  O    . SER A 1 154 ? 44.193  -16.505 19.006  1   45.652  ? 160  SER A O    1 ? 
ATOM   2171  C  CB   . SER A 1 154 ? 44.612  -17.681 16.129  1   44.07   ? 160  SER A CB   1 ? 
ATOM   2172  O  OG   . SER A 1 154 ? 44.02   -18.483 15.143  1   55.864  ? 160  SER A OG   1 ? 
ATOM   2173  H  H    . SER A 1 154 ? 43.121  -16.001 14.85   1   39.019  ? 160  SER A H    1 c 
ATOM   2174  H  HA   . SER A 1 154 ? 42.82   -17.251 17.074  1   44.079  ? 160  SER A HA   1 c 
ATOM   2175  H  HB2  . SER A 1 154 ? 45.347  -17.172 15.743  1   47.052  ? 160  SER A HB2  1 c 
ATOM   2176  H  HB3  . SER A 1 154 ? 44.971  -18.25  16.837  1   47.108  ? 160  SER A HB3  1 c 
ATOM   2177  H  HG   . SER A 1 154 ? 44.588  -18.997 14.814  0   57.94   ? 160  SER A HG   1 c 
ATOM   2178  N  N    . THR A 1 155 ? 45.227  -15.165 17.511  1   39.416  ? 161  THR A N    1 ? 
ATOM   2179  C  CA   . THR A 1 155 ? 46.144  -14.539 18.443  1   40.226  ? 161  THR A CA   1 ? 
ATOM   2180  C  C    . THR A 1 155 ? 45.501  -13.34  19.134  1   36.981  ? 161  THR A C    1 ? 
ATOM   2181  O  O    . THR A 1 155 ? 46.099  -12.796 20.04   1   45.542  ? 161  THR A O    1 ? 
ATOM   2182  C  CB   . THR A 1 155 ? 47.357  -14.064 17.63   1   46.884  ? 161  THR A CB   1 ? 
ATOM   2183  O  OG1  . THR A 1 155 ? 46.735  -13.12  16.751  1   42.027  ? 161  THR A OG1  1 ? 
ATOM   2184  C  CG2  . THR A 1 155 ? 48.078  -15.193 16.908  1   44.831  ? 161  THR A CG2  1 ? 
ATOM   2185  H  H    . THR A 1 155 ? 45.279  -14.926 16.631  1   41.522  ? 161  THR A H    1 c 
ATOM   2186  H  HA   . THR A 1 155 ? 46.433  -15.196 19.113  1   40.632  ? 161  THR A HA   1 c 
ATOM   2187  H  HB   . THR A 1 155 ? 47.994  -13.595 18.22   1   44.24   ? 161  THR A HB   1 c 
ATOM   2188  H  HG1  . THR A 1 155 ? 46.15   -13.517 16.28   0   41.43   ? 161  THR A HG1  1 c 
ATOM   2189  H  HG21 . THR A 1 155 ? 48.877  -14.844 16.477  1   45.412  ? 161  THR A HG21 1 c 
ATOM   2190  H  HG22 . THR A 1 155 ? 47.492  -15.577 16.235  1   45.362  ? 161  THR A HG22 1 c 
ATOM   2191  H  HG23 . THR A 1 155 ? 48.33   -15.879 17.548  1   45.412  ? 161  THR A HG23 1 c 
ATOM   2192  N  N    . LYS A 1 156 ? 44.399  -12.814 18.604  1   36.835  ? 162  LYS A N    1 ? 
ATOM   2193  C  CA   . LYS A 1 156 ? 43.695  -11.676 19.188  1   35.921  ? 162  LYS A CA   1 ? 
ATOM   2194  C  C    . LYS A 1 156 ? 44.485  -10.376 19.072  1   43.63   ? 162  LYS A C    1 ? 
ATOM   2195  O  O    . LYS A 1 156 ? 44.232  -9.455  19.864  1   42.714  ? 162  LYS A O    1 ? 
ATOM   2196  C  CB   . LYS A 1 156 ? 43.231  -11.918 20.628  1   43.923  ? 162  LYS A CB   1 ? 
ATOM   2197  C  CG   . LYS A 1 156 ? 42.725  -13.334 20.875  1   51.081  ? 162  LYS A CG   1 ? 
ATOM   2198  C  CD   . LYS A 1 156 ? 41.844  -13.555 22.094  1   57.916  ? 162  LYS A CD   1 ? 
ATOM   2199  C  CE   . LYS A 1 156 ? 41.146  -14.885 21.969  1   58.727  ? 162  LYS A CE   1 ? 
ATOM   2200  N  NZ   . LYS A 1 156 ? 40.197  -14.954 23.074  1   71.739  ? 162  LYS A NZ   1 ? 
ATOM   2201  H  H    . LYS A 1 156 ? 44.07   -13.172 17.831  1   36.754  ? 162  LYS A H    1 c 
ATOM   2202  H  HA   . LYS A 1 156 ? 42.87   -11.554 18.659  1   38.975  ? 162  LYS A HA   1 c 
ATOM   2203  H  HB2  . LYS A 1 156 ? 43.978  -11.74  21.24   1   43.449  ? 162  LYS A HB2  1 c 
ATOM   2204  H  HB3  . LYS A 1 156 ? 42.511  -11.286 20.841  1   43.439  ? 162  LYS A HB3  1 c 
ATOM   2205  H  HG2  . LYS A 1 156 ? 42.228  -13.619 20.078  1   50.682  ? 162  LYS A HG2  1 c 
ATOM   2206  H  HG3  . LYS A 1 156 ? 43.506  -13.925 20.951  1   50.612  ? 162  LYS A HG3  1 c 
ATOM   2207  H  HD2  . LYS A 1 156 ? 42.394  -13.549 22.908  1   56.551  ? 162  LYS A HD2  1 c 
ATOM   2208  H  HD3  . LYS A 1 156 ? 41.176  -12.838 22.154  1   56.553  ? 162  LYS A HD3  1 c 
ATOM   2209  H  HE2  . LYS A 1 156 ? 40.669  -14.948 21.122  1   61.341  ? 162  LYS A HE2  1 c 
ATOM   2210  H  HE3  . LYS A 1 156 ? 41.786  -15.617 22.035  1   61.383  ? 162  LYS A HE3  1 c 
ATOM   2211  H  HZ1  . LYS A 1 156 ? 39.568  -14.308 22.983  1   67.272  ? 162  LYS A HZ1  1 c 
ATOM   2212  H  HZ2  . LYS A 1 156 ? 40.63   -14.841 23.862  1   67.273  ? 162  LYS A HZ2  1 c 
ATOM   2213  H  HZ3  . LYS A 1 156 ? 39.79   -15.764 23.075  1   67.381  ? 162  LYS A HZ3  1 c 
ATOM   2214  N  N    . ARG A 1 157 ? 45.301  -10.241 17.994  1   42.577  ? 163  ARG A N    1 ? 
ATOM   2215  C  CA   . ARG A 1 157 ? 46.14   -9.059  17.777  1   37.811  ? 163  ARG A CA   1 ? 
ATOM   2216  C  C    . ARG A 1 157 ? 45.463  -8.111  16.792  1   37.208  ? 163  ARG A C    1 ? 
ATOM   2217  O  O    . ARG A 1 157 ? 44.709  -8.554  15.934  1   34.323  ? 163  ARG A O    1 ? 
ATOM   2218  C  CB   . ARG A 1 157 ? 47.486  -9.521  17.206  1   40.916  ? 163  ARG A CB   1 ? 
ATOM   2219  C  CG   . ARG A 1 157 ? 48.306  -10.434 18.113  1   39.445  ? 163  ARG A CG   1 ? 
ATOM   2220  C  CD   . ARG A 1 157 ? 48.241  -10.056 19.614  1   36.279  ? 163  ARG A CD   1 ? 
ATOM   2221  N  NE   . ARG A 1 157 ? 48.802  -8.712  19.816  1   34.965  ? 163  ARG A NE   1 ? 
ATOM   2222  C  CZ   . ARG A 1 157 ? 50.074  -8.443  20.104  1   36.904  ? 163  ARG A CZ   1 ? 
ATOM   2223  N  NH1  . ARG A 1 157 ? 50.95   -9.42   20.294  1   37.324  ? 163  ARG A NH1  1 ? 
ATOM   2224  N  NH2  . ARG A 1 157 ? 50.486  -7.196  20.171  1   34.711  ? 163  ARG A NH2  1 ? 
ATOM   2225  H  H    . ARG A 1 157 ? 45.327  -10.911 17.373  1   41.616  ? 163  ARG A H    1 c 
ATOM   2226  H  HA   . ARG A 1 157 ? 46.27   -8.592  18.638  1   39.121  ? 163  ARG A HA   1 c 
ATOM   2227  H  HB2  . ARG A 1 157 ? 47.319  -9.99   16.361  1   39.851  ? 163  ARG A HB2  1 c 
ATOM   2228  H  HB3  . ARG A 1 157 ? 48.022  -8.726  16.999  1   39.839  ? 163  ARG A HB3  1 c 
ATOM   2229  H  HG2  . ARG A 1 157 ? 47.987  -11.354 18.008  1   39.122  ? 163  ARG A HG2  1 c 
ATOM   2230  H  HG3  . ARG A 1 157 ? 49.243  -10.413 17.822  1   39.053  ? 163  ARG A HG3  1 c 
ATOM   2231  H  HD2  . ARG A 1 157 ? 47.314  -10.073 19.927  1   36.661  ? 163  ARG A HD2  1 c 
ATOM   2232  H  HD3  . ARG A 1 157 ? 48.748  -10.704 20.142  1   36.672  ? 163  ARG A HD3  1 c 
ATOM   2233  H  HE   . ARG A 1 157 ? 48.259  -8.036  19.745  1   35.738  ? 163  ARG A HE   1 c 
ATOM   2234  H  HH11 . ARG A 1 157 ? 50.992  -10.096 19.722  1   37.184  ? 163  ARG A HH11 1 c 
ATOM   2235  H  HH12 . ARG A 1 157 ? 51.495  -9.388  20.992  1   37.192  ? 163  ARG A HH12 1 c 
ATOM   2236  H  HH21 . ARG A 1 157 ? 50.118  -6.582  19.652  1   35.383  ? 163  ARG A HH21 1 c 
ATOM   2237  H  HH22 . ARG A 1 157 ? 51.135  -6.979  20.733  1   35.388  ? 163  ARG A HH22 1 c 
ATOM   2238  N  N    . SER A 1 158 ? 45.744  -6.808  16.879  1   33.833  ? 164  SER A N    1 ? 
ATOM   2239  C  CA   . SER A 1 158 ? 45.118  -5.912  15.94   1   36.634  ? 164  SER A CA   1 ? 
ATOM   2240  C  C    . SER A 1 158 ? 45.964  -5.803  14.673  1   36.131  ? 164  SER A C    1 ? 
ATOM   2241  O  O    . SER A 1 158 ? 45.49   -5.302  13.661  1   42.081  ? 164  SER A O    1 ? 
ATOM   2242  C  CB   . SER A 1 158 ? 44.755  -4.59   16.552  1   34.568  ? 164  SER A CB   1 ? 
ATOM   2243  O  OG   . SER A 1 158 ? 45.893  -3.908  17.061  1   37.715  ? 164  SER A OG   1 ? 
ATOM   2244  H  H    . SER A 1 158 ? 46.317  -6.485  17.513  1   35.304  ? 164  SER A H    1 c 
ATOM   2245  H  HA   . SER A 1 158 ? 44.264  -6.335  15.669  1   35.592  ? 164  SER A HA   1 c 
ATOM   2246  H  HB2  . SER A 1 158 ? 44.321  -4.033  15.878  1   35.761  ? 164  SER A HB2  1 c 
ATOM   2247  H  HB3  . SER A 1 158 ? 44.118  -4.736  17.277  1   35.761  ? 164  SER A HB3  1 c 
ATOM   2248  H  HG   . SER A 1 158 ? 45.649  -3.188  17.379  0   37.41   ? 164  SER A HG   1 c 
ATOM   2249  N  N    . LEU A 1 159 ? 47.178  -6.336  14.705  1   38.1    ? 165  LEU A N    1 ? 
ATOM   2250  C  CA   . LEU A 1 159 ? 48.055  -6.303  13.549  1   38.941  ? 165  LEU A CA   1 ? 
ATOM   2251  C  C    . LEU A 1 159 ? 47.656  -7.477  12.672  1   39.368  ? 165  LEU A C    1 ? 
ATOM   2252  O  O    . LEU A 1 159 ? 47.524  -8.596  13.138  1   38.426  ? 165  LEU A O    1 ? 
ATOM   2253  C  CB   . LEU A 1 159 ? 49.543  -6.382  13.904  1   40.599  ? 165  LEU A CB   1 ? 
ATOM   2254  C  CG   . LEU A 1 159 ? 50.572  -6.176  12.774  1   38.948  ? 165  LEU A CG   1 ? 
ATOM   2255  C  CD1  . LEU A 1 159 ? 50.666  -4.717  12.34   1   38.894  ? 165  LEU A CD1  1 ? 
ATOM   2256  C  CD2  . LEU A 1 159 ? 51.957  -6.627  13.254  1   42.725  ? 165  LEU A CD2  1 ? 
ATOM   2257  H  H    . LEU A 1 159 ? 47.483  -6.726  15.473  1   37.741  ? 165  LEU A H    1 c 
ATOM   2258  H  HA   . LEU A 1 159 ? 47.888  -5.46   13.061  1   39.103  ? 165  LEU A HA   1 c 
ATOM   2259  H  HB2  . LEU A 1 159 ? 49.722  -5.713  14.604  1   39.843  ? 165  LEU A HB2  1 c 
ATOM   2260  H  HB3  . LEU A 1 159 ? 49.709  -7.263  14.311  1   39.863  ? 165  LEU A HB3  1 c 
ATOM   2261  H  HG   . LEU A 1 159 ? 50.307  -6.728  11.994  1   39.907  ? 165  LEU A HG   1 c 
ATOM   2262  H  HD11 . LEU A 1 159 ? 49.781  -4.386  12.113  1   38.874  ? 165  LEU A HD11 1 c 
ATOM   2263  H  HD12 . LEU A 1 159 ? 51.246  -4.646  11.564  1   38.901  ? 165  LEU A HD12 1 c 
ATOM   2264  H  HD13 . LEU A 1 159 ? 51.032  -4.186  13.067  1   38.901  ? 165  LEU A HD13 1 c 
ATOM   2265  H  HD21 . LEU A 1 159 ? 51.915  -7.555  13.538  1   41.569  ? 165  LEU A HD21 1 c 
ATOM   2266  H  HD22 . LEU A 1 159 ? 52.237  -6.074  14.002  1   41.579  ? 165  LEU A HD22 1 c 
ATOM   2267  H  HD23 . LEU A 1 159 ? 52.597  -6.539  12.529  1   41.579  ? 165  LEU A HD23 1 c 
ATOM   2268  N  N    . PRO A 1 160 ? 47.441  -7.246  11.37   1   38.136  ? 166  PRO A N    1 ? 
ATOM   2269  C  CA   . PRO A 1 160 ? 47.088  -8.322  10.461  1   38.188  ? 166  PRO A CA   1 ? 
ATOM   2270  C  C    . PRO A 1 160 ? 48.246  -9.3    10.487  1   38.9    ? 166  PRO A C    1 ? 
ATOM   2271  O  O    . PRO A 1 160 ? 49.416  -8.888  10.375  1   33.372  ? 166  PRO A O    1 ? 
ATOM   2272  C  CB   . PRO A 1 160 ? 46.889  -7.677  9.07    1   41.861  ? 166  PRO A CB   1 ? 
ATOM   2273  C  CG   . PRO A 1 160 ? 47.268  -6.22   9.241   1   42.583  ? 166  PRO A CG   1 ? 
ATOM   2274  C  CD   . PRO A 1 160 ? 47.561  -5.949  10.717  1   38.648  ? 166  PRO A CD   1 ? 
ATOM   2275  H  HA   . PRO A 1 160 ? 46.252  -8.758  10.761  1   38.888  ? 166  PRO A HA   1 c 
ATOM   2276  H  HB2  . PRO A 1 160 ? 47.464  -8.11   8.397   1   41.143  ? 166  PRO A HB2  1 c 
ATOM   2277  H  HB3  . PRO A 1 160 ? 45.952  -7.76   8.781   1   41.06   ? 166  PRO A HB3  1 c 
ATOM   2278  H  HG2  . PRO A 1 160 ? 48.059  -6.014  8.701   1   41.5    ? 166  PRO A HG2  1 c 
ATOM   2279  H  HG3  . PRO A 1 160 ? 46.535  -5.645  8.936   1   41.5    ? 166  PRO A HG3  1 c 
ATOM   2280  H  HD2  . PRO A 1 160 ? 48.465  -5.584  10.827  1   39.344  ? 166  PRO A HD2  1 c 
ATOM   2281  H  HD3  . PRO A 1 160 ? 46.914  -5.313  11.087  1   39.301  ? 166  PRO A HD3  1 c 
ATOM   2282  N  N    . ASP A 1 161 ? 47.872  -10.583 10.601  1   34.928  ? 167  ASP A N    1 ? 
ATOM   2283  C  CA   . ASP A 1 161 ? 48.8    -11.699 10.708  1   33.734  ? 167  ASP A CA   1 ? 
ATOM   2284  C  C    . ASP A 1 161 ? 48.721  -12.448 9.388   1   34.407  ? 167  ASP A C    1 ? 
ATOM   2285  O  O    . ASP A 1 161 ? 47.725  -13.114 9.114   1   39.607  ? 167  ASP A O    1 ? 
ATOM   2286  C  CB   . ASP A 1 161 ? 48.509  -12.588 11.915  1   32.971  ? 167  ASP A CB   1 ? 
ATOM   2287  C  CG   . ASP A 1 161 ? 49.419  -13.819 12.09   1   33.611  ? 167  ASP A CG   1 ? 
ATOM   2288  O  OD1  . ASP A 1 161 ? 50.098  -14.242 11.124  1   33.255  ? 167  ASP A OD1  1 ? 
ATOM   2289  O  OD2  . ASP A 1 161 ? 49.484  -14.349 13.209  1   40.363  ? 167  ASP A OD2  1 ? 
ATOM   2290  H  H    . ASP A 1 161 ? 46.978  -10.772 10.61   1   35.601  ? 167  ASP A H    1 c 
ATOM   2291  H  HA   . ASP A 1 161 ? 49.709  -11.34  10.816  1   33.96   ? 167  ASP A HA   1 c 
ATOM   2292  H  HB2  . ASP A 1 161 ? 48.581  -12.042 12.726  1   33.289  ? 167  ASP A HB2  1 c 
ATOM   2293  H  HB3  . ASP A 1 161 ? 47.583  -12.904 11.85   1   33.289  ? 167  ASP A HB3  1 c 
ATOM   2294  N  N    . TYR A 1 162 ? 49.774  -12.353 8.571   1   36.184  ? 168  TYR A N    1 ? 
ATOM   2295  C  CA   . TYR A 1 162 ? 49.718  -12.836 7.198   1   36.946  ? 168  TYR A CA   1 ? 
ATOM   2296  C  C    . TYR A 1 162 ? 49.32   -14.309 7.116   1   37.172  ? 168  TYR A C    1 ? 
ATOM   2297  O  O    . TYR A 1 162 ? 49.093  -14.804 6.018   1   39.382  ? 168  TYR A O    1 ? 
ATOM   2298  C  CB   . TYR A 1 162 ? 51.046  -12.669 6.444   1   38.489  ? 168  TYR A CB   1 ? 
ATOM   2299  C  CG   . TYR A 1 162 ? 52.162  -13.617 6.843   1   36.349  ? 168  TYR A CG   1 ? 
ATOM   2300  C  CD1  . TYR A 1 162 ? 52.737  -13.56  8.109   1   43.265  ? 168  TYR A CD1  1 ? 
ATOM   2301  C  CD2  . TYR A 1 162 ? 52.701  -14.509 5.933   1   32.994  ? 168  TYR A CD2  1 ? 
ATOM   2302  C  CE1  . TYR A 1 162 ? 53.775  -14.403 8.479   1   38.756  ? 168  TYR A CE1  1 ? 
ATOM   2303  C  CE2  . TYR A 1 162 ? 53.728  -15.361 6.293   1   34.653  ? 168  TYR A CE2  1 ? 
ATOM   2304  C  CZ   . TYR A 1 162 ? 54.259  -15.324 7.569   1   37.111  ? 168  TYR A CZ   1 ? 
ATOM   2305  O  OH   . TYR A 1 162 ? 55.292  -16.164 7.906   1   36.816  ? 168  TYR A OH   1 ? 
ATOM   2306  H  H    . TYR A 1 162 ? 50.543  -11.962 8.871   1   35.979  ? 168  TYR A H    1 c 
ATOM   2307  H  HA   . TYR A 1 162 ? 49.027  -12.305 6.719   1   37.113  ? 168  TYR A HA   1 c 
ATOM   2308  H  HB2  . TYR A 1 162 ? 50.869  -12.778 5.484   1   37.663  ? 168  TYR A HB2  1 c 
ATOM   2309  H  HB3  . TYR A 1 162 ? 51.357  -11.748 6.58    1   37.638  ? 168  TYR A HB3  1 c 
ATOM   2310  H  HD1  . TYR A 1 162 ? 52.4    -12.947 8.741   1   40.304  ? 168  TYR A HD1  1 c 
ATOM   2311  H  HD2  . TYR A 1 162 ? 52.335  -14.567 5.065   1   34.275  ? 168  TYR A HD2  1 c 
ATOM   2312  H  HE1  . TYR A 1 162 ? 54.128  -14.363 9.347   1   39.27   ? 168  TYR A HE1  1 c 
ATOM   2313  H  HE2  . TYR A 1 162 ? 54.062  -15.982 5.667   1   34.892  ? 168  TYR A HE2  1 c 
ATOM   2314  H  HH   . TYR A 1 162 ? 54.969  -16.895 8.252   0   37.11   ? 168  TYR A HH   1 c 
ATOM   2315  N  N    . ARG A 1 163 ? 49.314  -15.041 8.236   1   41.027  ? 169  ARG A N    1 ? 
ATOM   2316  C  CA   . ARG A 1 163 ? 49.156  -16.49  8.173   1   38.217  ? 169  ARG A CA   1 ? 
ATOM   2317  C  C    . ARG A 1 163 ? 47.698  -16.896 8.355   1   38.638  ? 169  ARG A C    1 ? 
ATOM   2318  O  O    . ARG A 1 163 ? 47.419  -18.075 8.321   1   37.177  ? 169  ARG A O    1 ? 
ATOM   2319  C  CB   . ARG A 1 163 ? 49.993  -17.26  9.202   1   37.52   ? 169  ARG A CB   1 ? 
ATOM   2320  C  CG   . ARG A 1 163 ? 51.481  -17.029 9.033   1   40.211  ? 169  ARG A CG   1 ? 
ATOM   2321  C  CD   . ARG A 1 163 ? 52.283  -17.326 10.292  1   40.302  ? 169  ARG A CD   1 ? 
ATOM   2322  N  NE   . ARG A 1 163 ? 51.952  -16.461 11.423  1   38.402  ? 169  ARG A NE   1 ? 
ATOM   2323  C  CZ   . ARG A 1 163 ? 52.515  -16.537 12.604  1   35.445  ? 169  ARG A CZ   1 ? 
ATOM   2324  N  NH1  . ARG A 1 163 ? 53.407  -17.477 12.84   1   39.656  ? 169  ARG A NH1  1 ? 
ATOM   2325  N  NH2  . ARG A 1 163 ? 52.163  -15.681 13.543  1   33.345  ? 169  ARG A NH2  1 ? 
ATOM   2326  H  H    . ARG A 1 163 ? 49.427  -14.645 9.05    1   39.37   ? 169  ARG A H    1 c 
ATOM   2327  H  HA   . ARG A 1 163 ? 49.447  -16.792 7.275   1   38.69   ? 169  ARG A HA   1 c 
ATOM   2328  H  HB2  . ARG A 1 163 ? 49.724  -16.983 10.104  1   38.287  ? 169  ARG A HB2  1 c 
ATOM   2329  H  HB3  . ARG A 1 163 ? 49.809  -18.22  9.114   1   38.277  ? 169  ARG A HB3  1 c 
ATOM   2330  H  HG2  . ARG A 1 163 ? 51.813  -17.598 8.305   1   39.602  ? 169  ARG A HG2  1 c 
ATOM   2331  H  HG3  . ARG A 1 163 ? 51.633  -16.096 8.774   1   39.611  ? 169  ARG A HG3  1 c 
ATOM   2332  H  HD2  . ARG A 1 163 ? 52.126  -18.258 10.546  1   39.81   ? 169  ARG A HD2  1 c 
ATOM   2333  H  HD3  . ARG A 1 163 ? 53.236  -17.23  10.086  1   39.811  ? 169  ARG A HD3  1 c 
ATOM   2334  H  HE   . ARG A 1 163 ? 51.342  -15.851 11.303  1   38.021  ? 169  ARG A HE   1 c 
ATOM   2335  H  HH11 . ARG A 1 163 ? 53.574  -18.107 12.244  1   38.331  ? 169  ARG A HH11 1 c 
ATOM   2336  H  HH12 . ARG A 1 163 ? 53.844  -17.476 13.609  1   38.24   ? 169  ARG A HH12 1 c 
ATOM   2337  H  HH21 . ARG A 1 163 ? 51.658  -14.985 13.344  1   34.058  ? 169  ARG A HH21 1 c 
ATOM   2338  H  HH22 . ARG A 1 163 ? 52.436  -15.807 14.375  1   34.066  ? 169  ARG A HH22 1 c 
ATOM   2339  N  N    . GLU A 1 164 ? 46.786  -15.935 8.517   1   39.232  ? 170  GLU A N    1 ? 
ATOM   2340  C  CA   . GLU A 1 164 ? 45.4    -16.193 8.88    1   45.345  ? 170  GLU A CA   1 ? 
ATOM   2341  C  C    . GLU A 1 164 ? 44.519  -15.225 8.106   1   45.944  ? 170  GLU A C    1 ? 
ATOM   2342  O  O    . GLU A 1 164 ? 44.967  -14.13  7.771   1   43.113  ? 170  GLU A O    1 ? 
ATOM   2343  C  CB   . GLU A 1 164 ? 45.075  -15.757 10.312  1   44.133  ? 170  GLU A CB   1 ? 
ATOM   2344  C  CG   . GLU A 1 164 ? 45.543  -16.722 11.377  1   48.503  ? 170  GLU A CG   1 ? 
ATOM   2345  C  CD   . GLU A 1 164 ? 45.081  -16.344 12.766  1   42.96   ? 170  GLU A CD   1 ? 
ATOM   2346  O  OE1  . GLU A 1 164 ? 45.907  -16.382 13.678  1   48.997  ? 170  GLU A OE1  1 ? 
ATOM   2347  O  OE2  . GLU A 1 164 ? 43.891  -16.049 12.918  1   45.347  ? 170  GLU A OE2  1 ? 
ATOM   2348  H  H    . GLU A 1 164 ? 47.041  -15.067 8.396   1   40.403  ? 170  GLU A H    1 c 
ATOM   2349  H  HA   . GLU A 1 164 ? 45.155  -17.133 8.688   1   43.908  ? 170  GLU A HA   1 c 
ATOM   2350  H  HB2  . GLU A 1 164 ? 45.492  -14.885 10.478  1   45.386  ? 170  GLU A HB2  1 c 
ATOM   2351  H  HB3  . GLU A 1 164 ? 44.106  -15.645 10.398  1   45.382  ? 170  GLU A HB3  1 c 
ATOM   2352  H  HG2  . GLU A 1 164 ? 45.206  -17.62  11.168  1   46.168  ? 170  GLU A HG2  1 c 
ATOM   2353  H  HG3  . GLU A 1 164 ? 46.523  -16.76  11.37   1   46.182  ? 170  GLU A HG3  1 c 
ATOM   2354  N  N    . GLN A 1 165 ? 43.26   -15.613 7.875   1   44.378  ? 171  GLN A N    1 ? 
ATOM   2355  C  CA   . GLN A 1 165 ? 42.264  -14.708 7.325   1   39.427  ? 171  GLN A CA   1 ? 
ATOM   2356  C  C    . GLN A 1 165 ? 41.025  -14.659 8.227   1   42.377  ? 171  GLN A C    1 ? 
ATOM   2357  O  O    . GLN A 1 165 ? 40.601  -15.657 8.792   1   49.971  ? 171  GLN A O    1 ? 
ATOM   2358  C  CB   . GLN A 1 165 ? 41.923  -15.099 5.887   1   42.799  ? 171  GLN A CB   1 ? 
ATOM   2359  C  CG   . GLN A 1 165 ? 43.009  -14.857 4.836   1   37.551  ? 171  GLN A CG   1 ? 
ATOM   2360  C  CD   . GLN A 1 165 ? 43.578  -13.464 4.778   1   42.809  ? 171  GLN A CD   1 ? 
ATOM   2361  O  OE1  . GLN A 1 165 ? 42.93   -12.434 4.993   1   55.217  ? 171  GLN A OE1  1 ? 
ATOM   2362  N  NE2  . GLN A 1 165 ? 44.855  -13.413 4.46    1   61.634  ? 171  GLN A NE2  1 ? 
ATOM   2363  H  H    . GLN A 1 165 ? 43.014  -16.471 8.07    1   43.581  ? 171  GLN A H    1 c 
ATOM   2364  H  HA   . GLN A 1 165 ? 42.656  -13.8   7.304   1   41.628  ? 171  GLN A HA   1 c 
ATOM   2365  H  HB2  . GLN A 1 165 ? 41.694  -16.051 5.88    1   40.772  ? 171  GLN A HB2  1 c 
ATOM   2366  H  HB3  . GLN A 1 165 ? 41.12   -14.605 5.62    1   40.779  ? 171  GLN A HB3  1 c 
ATOM   2367  H  HG2  . GLN A 1 165 ? 43.748  -15.481 5.001   1   40.073  ? 171  GLN A HG2  1 c 
ATOM   2368  H  HG3  . GLN A 1 165 ? 42.644  -15.07  3.952   1   39.878  ? 171  GLN A HG3  1 c 
ATOM   2369  H  HE21 . GLN A 1 165 ? 45.328  -12.685 4.658   1   54.99   ? 171  GLN A HE21 1 c 
ATOM   2370  H  HE22 . GLN A 1 165 ? 45.244  -14.099 4.046   1   54.749  ? 171  GLN A HE22 1 c 
ATOM   2371  N  N    . VAL A 1 166 ? 40.436  -13.47  8.335   1   43.108  ? 172  VAL A N    1 ? 
ATOM   2372  C  CA   . VAL A 1 166 ? 39.151  -13.234 8.967   1   47.317  ? 172  VAL A CA   1 ? 
ATOM   2373  C  C    . VAL A 1 166 ? 38.256  -12.44  8.006   1   48.886  ? 172  VAL A C    1 ? 
ATOM   2374  O  O    . VAL A 1 166 ? 38.766  -11.744 7.129   1   42.886  ? 172  VAL A O    1 ? 
ATOM   2375  C  CB   . VAL A 1 166 ? 39.487  -12.482 10.273  1   53.53   ? 172  VAL A CB   1 ? 
ATOM   2376  C  CG1  . VAL A 1 166 ? 38.366  -11.588 10.788  1   56.527  ? 172  VAL A CG1  1 ? 
ATOM   2377  C  CG2  . VAL A 1 166 ? 39.915  -13.463 11.345  1   60.286  ? 172  VAL A CG2  1 ? 
ATOM   2378  H  H    . VAL A 1 166 ? 40.872  -12.748 7.983   1   43.903  ? 172  VAL A H    1 c 
ATOM   2379  H  HA   . VAL A 1 166 ? 38.728  -14.088 9.18    1   47.854  ? 172  VAL A HA   1 c 
ATOM   2380  H  HB   . VAL A 1 166 ? 40.26   -11.899 10.081  1   53.907  ? 172  VAL A HB   1 c 
ATOM   2381  H  HG11 . VAL A 1 166 ? 37.536  -12.094 10.82   1   55.596  ? 172  VAL A HG11 1 c 
ATOM   2382  H  HG12 . VAL A 1 166 ? 38.257  -10.826 10.194  1   55.592  ? 172  VAL A HG12 1 c 
ATOM   2383  H  HG13 . VAL A 1 166 ? 38.586  -11.271 11.68   1   55.653  ? 172  VAL A HG13 1 c 
ATOM   2384  H  HG21 . VAL A 1 166 ? 40.137  -12.979 12.159  1   58.143  ? 172  VAL A HG21 1 c 
ATOM   2385  H  HG22 . VAL A 1 166 ? 40.695  -13.957 11.041  1   58.092  ? 172  VAL A HG22 1 c 
ATOM   2386  H  HG23 . VAL A 1 166 ? 39.19   -14.084 11.526  1   58.097  ? 172  VAL A HG23 1 c 
ATOM   2387  N  N    . ILE A 1 167 ? 36.923  -12.575 8.139   1   41.461  ? 173  ILE A N    1 ? 
ATOM   2388  C  CA   . ILE A 1 167 ? 35.972  -11.787 7.359   1   38.036  ? 173  ILE A CA   1 ? 
ATOM   2389  C  C    . ILE A 1 167 ? 35.254  -10.816 8.29    1   38.296  ? 173  ILE A C    1 ? 
ATOM   2390  O  O    . ILE A 1 167 ? 34.766  -11.232 9.329   1   39.156  ? 173  ILE A O    1 ? 
ATOM   2391  C  CB   . ILE A 1 167 ? 34.956  -12.686 6.611   1   36.92   ? 173  ILE A CB   1 ? 
ATOM   2392  C  CG1  . ILE A 1 167 ? 35.611  -13.572 5.558   1   36.68   ? 173  ILE A CG1  1 ? 
ATOM   2393  C  CG2  . ILE A 1 167 ? 33.844  -11.861 5.96    1   34.077  ? 173  ILE A CG2  1 ? 
ATOM   2394  C  CD1  . ILE A 1 167 ? 34.666  -14.615 4.973   1   36.606  ? 173  ILE A CD1  1 ? 
ATOM   2395  H  H    . ILE A 1 167 ? 36.598  -13.182 8.74    1   42.37   ? 173  ILE A H    1 c 
ATOM   2396  H  HA   . ILE A 1 167 ? 36.468  -11.273 6.697   1   38.533  ? 173  ILE A HA   1 c 
ATOM   2397  H  HB   . ILE A 1 167 ? 34.542  -13.274 7.272   1   36.587  ? 173  ILE A HB   1 c 
ATOM   2398  H  HG12 . ILE A 1 167 ? 35.946  -13.006 4.833   1   36.722  ? 173  ILE A HG12 1 c 
ATOM   2399  H  HG13 . ILE A 1 167 ? 36.377  -14.03  5.961   1   36.741  ? 173  ILE A HG13 1 c 
ATOM   2400  H  HG21 . ILE A 1 167 ? 33.23   -12.449 5.492   1   34.915  ? 173  ILE A HG21 1 c 
ATOM   2401  H  HG22 . ILE A 1 167 ? 34.232  -11.232 5.329   1   34.898  ? 173  ILE A HG22 1 c 
ATOM   2402  H  HG23 . ILE A 1 167 ? 33.357  -11.371 6.643   1   34.912  ? 173  ILE A HG23 1 c 
ATOM   2403  H  HD11 . ILE A 1 167 ? 34.23   -15.102 5.698   1   36.621  ? 173  ILE A HD11 1 c 
ATOM   2404  H  HD12 . ILE A 1 167 ? 35.177  -15.24  4.425   1   36.621  ? 173  ILE A HD12 1 c 
ATOM   2405  H  HD13 . ILE A 1 167 ? 33.988  -14.183 4.42    1   36.6    ? 173  ILE A HD13 1 c 
ATOM   2406  N  N    . ASP A 1 168 ? 35.129  -9.546  7.888   1   36.028  ? 174  ASP A N    1 ? 
ATOM   2407  C  CA   . ASP A 1 168 ? 34.45   -8.572  8.716   1   34.157  ? 174  ASP A CA   1 ? 
ATOM   2408  C  C    . ASP A 1 168 ? 33.625  -7.686  7.803   1   31.045  ? 174  ASP A C    1 ? 
ATOM   2409  O  O    . ASP A 1 168 ? 33.68   -7.846  6.606   1   41.614  ? 174  ASP A O    1 ? 
ATOM   2410  C  CB   . ASP A 1 168 ? 35.415  -7.762  9.575   1   33.185  ? 174  ASP A CB   1 ? 
ATOM   2411  C  CG   . ASP A 1 168 ? 36.104  -6.618  8.839   1   32.339  ? 174  ASP A CG   1 ? 
ATOM   2412  O  OD1  . ASP A 1 168 ? 36.6    -6.919  7.744   1   33.307  ? 174  ASP A OD1  1 ? 
ATOM   2413  O  OD2  . ASP A 1 168 ? 36.143  -5.441  9.343   1   29.785  ? 174  ASP A OD2  1 ? 
ATOM   2414  H  H    . ASP A 1 168 ? 35.477  -9.284  7.085   1   36.114  ? 174  ASP A H    1 c 
ATOM   2415  H  HA   . ASP A 1 168 ? 33.836  -9.048  9.32    1   33.784  ? 174  ASP A HA   1 c 
ATOM   2416  H  HB2  . ASP A 1 168 ? 34.924  -7.387  10.336  1   33.194  ? 174  ASP A HB2  1 c 
ATOM   2417  H  HB3  . ASP A 1 168 ? 36.106  -8.362  9.926   1   33.204  ? 174  ASP A HB3  1 c 
ATOM   2418  N  N    . LEU A 1 169 ? 32.93   -6.71   8.381   1   30.134  ? 175  LEU A N    1 ? 
ATOM   2419  C  CA   . LEU A 1 169 ? 32.183  -5.731  7.611   1   33.935  ? 175  LEU A CA   1 ? 
ATOM   2420  C  C    . LEU A 1 169 ? 33.05   -5.154  6.488   1   30.788  ? 175  LEU A C    1 ? 
ATOM   2421  O  O    . LEU A 1 169 ? 32.62   -5.125  5.339   1   34.331  ? 175  LEU A O    1 ? 
ATOM   2422  C  CB   . LEU A 1 169 ? 31.713  -4.616  8.542   1   34.517  ? 175  LEU A CB   1 ? 
ATOM   2423  C  CG   . LEU A 1 169 ? 30.793  -5.042  9.684   1   40.338  ? 175  LEU A CG   1 ? 
ATOM   2424  C  CD1  . LEU A 1 169 ? 30.414  -3.817  10.469  1   39.089  ? 175  LEU A CD1  1 ? 
ATOM   2425  C  CD2  . LEU A 1 169 ? 29.57   -5.755  9.121   1   43.442  ? 175  LEU A CD2  1 ? 
ATOM   2426  H  H    . LEU A 1 169 ? 32.925  -6.651  9.293   1   31.353  ? 175  LEU A H    1 c 
ATOM   2427  H  HA   . LEU A 1 169 ? 31.397  -6.179  7.212   1   32.787  ? 175  LEU A HA   1 c 
ATOM   2428  H  HB2  . LEU A 1 169 ? 32.509  -4.184  8.93    1   35.564  ? 175  LEU A HB2  1 c 
ATOM   2429  H  HB3  . LEU A 1 169 ? 31.243  -3.941  8       1   35.615  ? 175  LEU A HB3  1 c 
ATOM   2430  H  HG   . LEU A 1 169 ? 31.285  -5.664  10.279  1   39.386  ? 175  LEU A HG   1 c 
ATOM   2431  H  HD11 . LEU A 1 169 ? 31.216  -3.39   10.814  1   39.457  ? 175  LEU A HD11 1 c 
ATOM   2432  H  HD12 . LEU A 1 169 ? 29.839  -4.07   11.21   1   39.457  ? 175  LEU A HD12 1 c 
ATOM   2433  H  HD13 . LEU A 1 169 ? 29.94   -3.195  9.891   1   39.457  ? 175  LEU A HD13 1 c 
ATOM   2434  H  HD21 . LEU A 1 169 ? 29.813  -6.656  8.854   1   42.31   ? 175  LEU A HD21 1 c 
ATOM   2435  H  HD22 . LEU A 1 169 ? 29.238  -5.268  8.349   1   42.268  ? 175  LEU A HD22 1 c 
ATOM   2436  H  HD23 . LEU A 1 169 ? 28.876  -5.795  9.801   1   42.39   ? 175  LEU A HD23 1 c 
ATOM   2437  N  N    . GLY A 1 170 ? 34.239  -4.675  6.859   1   30.297  ? 176  GLY A N    1 ? 
ATOM   2438  C  CA   . GLY A 1 170 ? 35.176  -3.999  5.959   1   30.974  ? 176  GLY A CA   1 ? 
ATOM   2439  C  C    . GLY A 1 170 ? 35.655  -4.921  4.835   1   30.26   ? 176  GLY A C    1 ? 
ATOM   2440  O  O    . GLY A 1 170 ? 35.446  -4.608  3.662   1   33.538  ? 176  GLY A O    1 ? 
ATOM   2441  H  H    . GLY A 1 170 ? 34.48   -4.761  7.736   1   30.649  ? 176  GLY A H    1 c 
ATOM   2442  H  HA2  . GLY A 1 170 ? 34.732  -3.209  5.571   1   30.704  ? 176  GLY A HA2  1 c 
ATOM   2443  H  HA3  . GLY A 1 170 ? 35.952  -3.685  6.48    1   30.663  ? 176  GLY A HA3  1 c 
ATOM   2444  N  N    . SER A 1 171 ? 36.163  -6.112  5.189   1   32.129  ? 177  SER A N    1 ? 
ATOM   2445  C  CA   . SER A 1 171 ? 36.693  -7.046  4.205   1   34.017  ? 177  SER A CA   1 ? 
ATOM   2446  C  C    . SER A 1 171 ? 35.596  -7.568  3.268   1   36.362  ? 177  SER A C    1 ? 
ATOM   2447  O  O    . SER A 1 171 ? 35.844  -7.835  2.079   1   34.047  ? 177  SER A O    1 ? 
ATOM   2448  C  CB   . SER A 1 171 ? 37.489  -8.182  4.854   1   35.52   ? 177  SER A CB   1 ? 
ATOM   2449  O  OG   . SER A 1 171 ? 36.682  -9.257  5.339   1   33.356  ? 177  SER A OG   1 ? 
ATOM   2450  H  H    . SER A 1 171 ? 36.179  -6.346  6.071   1   32.105  ? 177  SER A H    1 c 
ATOM   2451  H  HA   . SER A 1 171 ? 37.328  -6.535  3.642   1   34.305  ? 177  SER A HA   1 c 
ATOM   2452  H  HB2  . SER A 1 171 ? 38.122  -8.534  4.2     1   34.587  ? 177  SER A HB2  1 c 
ATOM   2453  H  HB3  . SER A 1 171 ? 38.007  -7.816  5.593   1   34.596  ? 177  SER A HB3  1 c 
ATOM   2454  H  HG   . SER A 1 171 ? 37.205  -9.851  5.67    0   32.79   ? 177  SER A HG   1 c 
ATOM   2455  N  N    . GLY A 1 172 ? 34.387  -7.772  3.794   1   34.849  ? 178  GLY A N    1 ? 
ATOM   2456  C  CA   . GLY A 1 172 ? 33.264  -8.135  2.933   1   34.878  ? 178  GLY A CA   1 ? 
ATOM   2457  C  C    . GLY A 1 172 ? 33.019  -7.116  1.81    1   32.933  ? 178  GLY A C    1 ? 
ATOM   2458  O  O    . GLY A 1 172 ? 32.945  -7.486  0.634   1   30.205  ? 178  GLY A O    1 ? 
ATOM   2459  H  H    . GLY A 1 172 ? 34.254  -7.694  4.695   1   35.182  ? 178  GLY A H    1 c 
ATOM   2460  H  HA2  . GLY A 1 172 ? 33.441  -9.019  2.535   1   34.428  ? 178  GLY A HA2  1 c 
ATOM   2461  H  HA3  . GLY A 1 172 ? 32.452  -8.212  3.484   1   34.429  ? 178  GLY A HA3  1 c 
ATOM   2462  N  N    . ASN A 1 173 ? 32.918  -5.821  2.159   1   33.012  ? 179  ASN A N    1 ? 
ATOM   2463  C  CA   . ASN A 1 173 ? 32.675  -4.773  1.169   1   29.228  ? 179  ASN A CA   1 ? 
ATOM   2464  C  C    . ASN A 1 173 ? 33.814  -4.698  0.157   1   31.773  ? 179  ASN A C    1 ? 
ATOM   2465  O  O    . ASN A 1 173 ? 33.581  -4.406  -1.017  1   36.875  ? 179  ASN A O    1 ? 
ATOM   2466  C  CB   . ASN A 1 173 ? 32.522  -3.393  1.783   1   33.532  ? 179  ASN A CB   1 ? 
ATOM   2467  C  CG   . ASN A 1 173 ? 31.098  -3.064  2.176   1   39.548  ? 179  ASN A CG   1 ? 
ATOM   2468  O  OD1  . ASN A 1 173 ? 30.332  -3.95   2.575   1   37.115  ? 179  ASN A OD1  1 ? 
ATOM   2469  N  ND2  . ASN A 1 173 ? 30.723  -1.794  2.048   1   38.115  ? 179  ASN A ND2  1 ? 
ATOM   2470  H  H    . ASN A 1 173 ? 33      -5.587  3.038   1   32.159  ? 179  ASN A H    1 c 
ATOM   2471  H  HA   . ASN A 1 173 ? 31.842  -4.985  0.69    1   31.24   ? 179  ASN A HA   1 c 
ATOM   2472  H  HB2  . ASN A 1 173 ? 33.089  -3.334  2.577   1   33.804  ? 179  ASN A HB2  1 c 
ATOM   2473  H  HB3  . ASN A 1 173 ? 32.836  -2.723  1.143   1   33.805  ? 179  ASN A HB3  1 c 
ATOM   2474  H  HD21 . ASN A 1 173 ? 29.882  -1.565  2.218   1   38.515  ? 179  ASN A HD21 1 c 
ATOM   2475  H  HD22 . ASN A 1 173 ? 31.308  -1.178  1.797   1   38.444  ? 179  ASN A HD22 1 c 
ATOM   2476  N  N    . PHE A 1 174 ? 35.041  -4.928  0.645   1   31.861  ? 180  PHE A N    1 ? 
ATOM   2477  C  CA   . PHE A 1 174 ? 36.257  -4.748  -0.115  1   30.936  ? 180  PHE A CA   1 ? 
ATOM   2478  C  C    . PHE A 1 174 ? 36.301  -5.899  -1.099  1   25.905  ? 180  PHE A C    1 ? 
ATOM   2479  O  O    . PHE A 1 174 ? 36.693  -5.718  -2.234  1   28.303  ? 180  PHE A O    1 ? 
ATOM   2480  C  CB   . PHE A 1 174 ? 37.444  -4.638  0.861   1   30.23   ? 180  PHE A CB   1 ? 
ATOM   2481  C  CG   . PHE A 1 174 ? 38.7    -3.896  0.401   1   27.937  ? 180  PHE A CG   1 ? 
ATOM   2482  C  CD1  . PHE A 1 174 ? 39.124  -3.911  -0.92   1   29.667  ? 180  PHE A CD1  1 ? 
ATOM   2483  C  CD2  . PHE A 1 174 ? 39.465  -3.164  1.318   1   37.974  ? 180  PHE A CD2  1 ? 
ATOM   2484  C  CE1  . PHE A 1 174 ? 40.232  -3.177  -1.324  1   27.182  ? 180  PHE A CE1  1 ? 
ATOM   2485  C  CE2  . PHE A 1 174 ? 40.616  -2.473  0.926   1   28.602  ? 180  PHE A CE2  1 ? 
ATOM   2486  C  CZ   . PHE A 1 174 ? 41.009  -2.51   -0.395  1   29.766  ? 180  PHE A CZ   1 ? 
ATOM   2487  H  H    . PHE A 1 174 ? 35.116  -5.209  1.511   1   31.6    ? 180  PHE A H    1 c 
ATOM   2488  H  HA   . PHE A 1 174 ? 36.187  -3.897  -0.625  1   30.026  ? 180  PHE A HA   1 c 
ATOM   2489  H  HB2  . PHE A 1 174 ? 37.12   -4.202  1.68    1   29.941  ? 180  PHE A HB2  1 c 
ATOM   2490  H  HB3  . PHE A 1 174 ? 37.706  -5.55   1.117   1   29.843  ? 180  PHE A HB3  1 c 
ATOM   2491  H  HD1  . PHE A 1 174 ? 38.613  -4.368  -1.566  1   28.72   ? 180  PHE A HD1  1 c 
ATOM   2492  H  HD2  . PHE A 1 174 ? 39.208  -3.155  2.226   1   33.013  ? 180  PHE A HD2  1 c 
ATOM   2493  H  HE1  . PHE A 1 174 ? 40.512  -3.216  -2.224  1   28.427  ? 180  PHE A HE1  1 c 
ATOM   2494  H  HE2  . PHE A 1 174 ? 41.124  -1.993  1.561   1   30.772  ? 180  PHE A HE2  1 c 
ATOM   2495  H  HZ   . PHE A 1 174 ? 41.771  -2.029  -0.675  1   28.931  ? 180  PHE A HZ   1 c 
ATOM   2496  N  N    . GLY A 1 175 ? 35.835  -7.065  -0.668  1   32.52   ? 181  GLY A N    1 ? 
ATOM   2497  C  CA   . GLY A 1 175 ? 35.786  -8.255  -1.51   1   34.813  ? 181  GLY A CA   1 ? 
ATOM   2498  C  C    . GLY A 1 175 ? 34.722  -8.182  -2.603  1   37.751  ? 181  GLY A C    1 ? 
ATOM   2499  O  O    . GLY A 1 175 ? 34.978  -8.569  -3.769  1   33.787  ? 181  GLY A O    1 ? 
ATOM   2500  H  H    . GLY A 1 175 ? 35.543  -7.134  0.195   1   31.281  ? 181  GLY A H    1 c 
ATOM   2501  H  HA2  . GLY A 1 175 ? 36.67   -8.385  -1.927  1   34.786  ? 181  GLY A HA2  1 c 
ATOM   2502  H  HA3  . GLY A 1 175 ? 35.609  -9.039  -0.938  1   34.86   ? 181  GLY A HA3  1 c 
ATOM   2503  N  N    . SER A 1 176 ? 33.523  -7.703  -2.219  1   34.718  ? 182  SER A N    1 ? 
ATOM   2504  C  CA   . SER A 1 176 ? 32.453  -7.525  -3.197  1   33.596  ? 182  SER A CA   1 ? 
ATOM   2505  C  C    . SER A 1 176 ? 32.877  -6.508  -4.269  1   30.931  ? 182  SER A C    1 ? 
ATOM   2506  O  O    . SER A 1 176 ? 32.738  -6.782  -5.456  1   30.153  ? 182  SER A O    1 ? 
ATOM   2507  C  CB   . SER A 1 176 ? 31.125  -7.21   -2.574  1   31.668  ? 182  SER A CB   1 ? 
ATOM   2508  O  OG   . SER A 1 176 ? 31.217  -6.097  -1.714  1   31.706  ? 182  SER A OG   1 ? 
ATOM   2509  H  H    . SER A 1 176 ? 33.37   -7.489  -1.343  1   35.117  ? 182  SER A H    1 c 
ATOM   2510  H  HA   . SER A 1 176 ? 32.348  -8.396  -3.659  1   32.942  ? 182  SER A HA   1 c 
ATOM   2511  H  HB2  . SER A 1 176 ? 30.476  -7.022  -3.278  1   32.1    ? 182  SER A HB2  1 c 
ATOM   2512  H  HB3  . SER A 1 176 ? 30.813  -7.985  -2.07   1   32.105  ? 182  SER A HB3  1 c 
ATOM   2513  H  HG   . SER A 1 176 ? 30.477  -5.927  -1.361  0   30.63   ? 182  SER A HG   1 c 
ATOM   2514  N  N    . MET A 1 177 ? 33.524  -5.407  -3.862  1   28.92   ? 183  MET A N    1 ? 
ATOM   2515  C  CA   . MET A 1 177 ? 33.986  -4.415  -4.819  1   26.946  ? 183  MET A CA   1 ? 
ATOM   2516  C  C    . MET A 1 177 ? 35.003  -5.012  -5.804  1   26.299  ? 183  MET A C    1 ? 
ATOM   2517  O  O    . MET A 1 177 ? 34.924  -4.793  -7.001  1   27.846  ? 183  MET A O    1 ? 
ATOM   2518  C  CB   . MET A 1 177 ? 34.594  -3.232  -4.069  1   26.542  ? 183  MET A CB   1 ? 
ATOM   2519  C  CG   . MET A 1 177 ? 35.267  -2.215  -4.976  1   27.334  ? 183  MET A CG   1 ? 
ATOM   2520  S  SD   . MET A 1 177 ? 35.992  -0.9    -3.981  1   33.76   ? 183  MET A SD   1 ? 
ATOM   2521  C  CE   . MET A 1 177 ? 37.335  -1.755  -3.156  1   34.006  ? 183  MET A CE   1 ? 
ATOM   2522  H  H    . MET A 1 177 ? 33.675  -5.271  -2.971  1   28.954  ? 183  MET A H    1 c 
ATOM   2523  H  HA   . MET A 1 177 ? 33.202  -4.103  -5.337  1   27.127  ? 183  MET A HA   1 c 
ATOM   2524  H  HB2  . MET A 1 177 ? 33.885  -2.786  -3.559  1   26.83   ? 183  MET A HB2  1 c 
ATOM   2525  H  HB3  . MET A 1 177 ? 35.253  -3.575  -3.429  1   26.904  ? 183  MET A HB3  1 c 
ATOM   2526  H  HG2  . MET A 1 177 ? 35.97   -2.645  -5.501  1   28.247  ? 183  MET A HG2  1 c 
ATOM   2527  H  HG3  . MET A 1 177 ? 34.61   -1.831  -5.591  1   28.25   ? 183  MET A HG3  1 c 
ATOM   2528  H  HE1  . MET A 1 177 ? 37.85   -1.117  -2.628  1   33.928  ? 183  MET A HE1  1 c 
ATOM   2529  H  HE2  . MET A 1 177 ? 36.971  -2.442  -2.568  1   33.879  ? 183  MET A HE2  1 c 
ATOM   2530  H  HE3  . MET A 1 177 ? 37.914  -2.169  -3.822  1   33.928  ? 183  MET A HE3  1 c 
ATOM   2531  N  N    . LEU A 1 178 ? 35.994  -5.75   -5.295  1   31.922  ? 184  LEU A N    1 ? 
ATOM   2532  C  CA   . LEU A 1 178 ? 37.075  -6.282  -6.111  1   29.668  ? 184  LEU A CA   1 ? 
ATOM   2533  C  C    . LEU A 1 178 ? 36.575  -7.413  -6.983  1   29.133  ? 184  LEU A C    1 ? 
ATOM   2534  O  O    . LEU A 1 178 ? 37.058  -7.577  -8.116  1   35.502  ? 184  LEU A O    1 ? 
ATOM   2535  C  CB   . LEU A 1 178 ? 38.28   -6.692  -5.272  1   30.029  ? 184  LEU A CB   1 ? 
ATOM   2536  C  CG   . LEU A 1 178 ? 39.045  -5.568  -4.574  1   28.968  ? 184  LEU A CG   1 ? 
ATOM   2537  C  CD1  . LEU A 1 178 ? 39.987  -6.257  -3.609  1   34.42   ? 184  LEU A CD1  1 ? 
ATOM   2538  C  CD2  . LEU A 1 178 ? 39.832  -4.619  -5.454  1   30.9    ? 184  LEU A CD2  1 ? 
ATOM   2539  H  H    . LEU A 1 178 ? 35.997  -5.927  -4.398  1   29.953  ? 184  LEU A H    1 c 
ATOM   2540  H  HA   . LEU A 1 178 ? 37.364  -5.555  -6.72   1   30.048  ? 184  LEU A HA   1 c 
ATOM   2541  H  HB2  . LEU A 1 178 ? 37.97   -7.329  -4.586  1   29.748  ? 184  LEU A HB2  1 c 
ATOM   2542  H  HB3  . LEU A 1 178 ? 38.909  -7.177  -5.855  1   29.712  ? 184  LEU A HB3  1 c 
ATOM   2543  H  HG   . LEU A 1 178 ? 38.398  -5.033  -4.046  1   30.469  ? 184  LEU A HG   1 c 
ATOM   2544  H  HD11 . LEU A 1 178 ? 39.473  -6.746  -2.944  1   32.675  ? 184  LEU A HD11 1 c 
ATOM   2545  H  HD12 . LEU A 1 178 ? 40.54   -5.593  -3.165  1   32.684  ? 184  LEU A HD12 1 c 
ATOM   2546  H  HD13 . LEU A 1 178 ? 40.556  -6.876  -4.096  1   32.68   ? 184  LEU A HD13 1 c 
ATOM   2547  H  HD21 . LEU A 1 178 ? 39.229  -4.175  -6.074  1   30.314  ? 184  LEU A HD21 1 c 
ATOM   2548  H  HD22 . LEU A 1 178 ? 40.499  -5.118  -5.955  1   30.314  ? 184  LEU A HD22 1 c 
ATOM   2549  H  HD23 . LEU A 1 178 ? 40.274  -3.953  -4.901  1   30.314  ? 184  LEU A HD23 1 c 
ATOM   2550  N  N    . SER A 1 179 ? 35.568  -8.142  -6.495  1   27.66   ? 185  SER A N    1 ? 
ATOM   2551  C  CA   . SER A 1 179 ? 34.9    -9.125  -7.344  1   29.558  ? 185  SER A CA   1 ? 
ATOM   2552  C  C    . SER A 1 179 ? 34.231  -8.489  -8.574  1   34.242  ? 185  SER A C    1 ? 
ATOM   2553  O  O    . SER A 1 179 ? 34.295  -9.034  -9.686  1   37.398  ? 185  SER A O    1 ? 
ATOM   2554  C  CB   . SER A 1 179 ? 33.938  -9.984  -6.569  1   30.292  ? 185  SER A CB   1 ? 
ATOM   2555  O  OG   . SER A 1 179 ? 34.582  -10.704 -5.514  1   33.534  ? 185  SER A OG   1 ? 
ATOM   2556  H  H    . SER A 1 179 ? 35.297  -8.04   -5.628  1   28.468  ? 185  SER A H    1 c 
ATOM   2557  H  HA   . SER A 1 179 ? 35.608  -9.729  -7.687  1   30.139  ? 185  SER A HA   1 c 
ATOM   2558  H  HB2  . SER A 1 179 ? 33.239  -9.417  -6.191  1   30.864  ? 185  SER A HB2  1 c 
ATOM   2559  H  HB3  . SER A 1 179 ? 33.514  -10.617 -7.178  1   30.878  ? 185  SER A HB3  1 c 
ATOM   2560  H  HG   . SER A 1 179 ? 34.003  -11.172 -5.104  0   33.09   ? 185  SER A HG   1 c 
ATOM   2561  N  N    . TRP A 1 180 ? 33.592  -7.334  -8.405  1   30.74   ? 186  TRP A N    1 ? 
ATOM   2562  C  CA   . TRP A 1 180 ? 32.982  -6.662  -9.536  1   30.024  ? 186  TRP A CA   1 ? 
ATOM   2563  C  C    . TRP A 1 180 ? 34.039  -6.122  -10.495 1   28.585  ? 186  TRP A C    1 ? 
ATOM   2564  O  O    . TRP A 1 180 ? 33.834  -6.168  -11.722 1   32.261  ? 186  TRP A O    1 ? 
ATOM   2565  C  CB   . TRP A 1 180 ? 32.051  -5.538  -9.053  1   30.351  ? 186  TRP A CB   1 ? 
ATOM   2566  C  CG   . TRP A 1 180 ? 30.736  -6.046  -8.564  1   30.909  ? 186  TRP A CG   1 ? 
ATOM   2567  C  CD1  . TRP A 1 180 ? 30.265  -6.101  -7.281  1   29.848  ? 186  TRP A CD1  1 ? 
ATOM   2568  C  CD2  . TRP A 1 180 ? 29.711  -6.607  -9.403  1   28.682  ? 186  TRP A CD2  1 ? 
ATOM   2569  N  NE1  . TRP A 1 180 ? 29.02   -6.655  -7.264  1   27.705  ? 186  TRP A NE1  1 ? 
ATOM   2570  C  CE2  . TRP A 1 180 ? 28.641  -6.955  -8.552  1   28.224  ? 186  TRP A CE2  1 ? 
ATOM   2571  C  CE3  . TRP A 1 180 ? 29.606  -6.83   -10.78  1   26.23   ? 186  TRP A CE3  1 ? 
ATOM   2572  C  CZ2  . TRP A 1 180 ? 27.469  -7.527  -9.045  1   25.223  ? 186  TRP A CZ2  1 ? 
ATOM   2573  C  CZ3  . TRP A 1 180 ? 28.444  -7.38   -11.267 1   26.578  ? 186  TRP A CZ3  1 ? 
ATOM   2574  C  CH2  . TRP A 1 180 ? 27.383  -7.713  -10.409 1   28.341  ? 186  TRP A CH2  1 ? 
ATOM   2575  H  H    . TRP A 1 180 ? 33.53   -6.959  -7.574  1   31.323  ? 186  TRP A H    1 c 
ATOM   2576  H  HA   . TRP A 1 180 ? 32.429  -7.328  -10.027 1   30.008  ? 186  TRP A HA   1 c 
ATOM   2577  H  HB2  . TRP A 1 180 ? 32.496  -5.05   -8.328  1   30.41   ? 186  TRP A HB2  1 c 
ATOM   2578  H  HB3  . TRP A 1 180 ? 31.897  -4.916  -9.796  1   30.396  ? 186  TRP A HB3  1 c 
ATOM   2579  H  HD1  . TRP A 1 180 ? 30.724  -5.802  -6.514  1   29.545  ? 186  TRP A HD1  1 c 
ATOM   2580  H  HE1  . TRP A 1 180 ? 28.527  -6.766  -6.553  1   28.322  ? 186  TRP A HE1  1 c 
ATOM   2581  H  HE3  . TRP A 1 180 ? 30.307  -6.586  -11.36  1   26.882  ? 186  TRP A HE3  1 c 
ATOM   2582  H  HZ2  . TRP A 1 180 ? 26.759  -7.76   -8.471  1   26.616  ? 186  TRP A HZ2  1 c 
ATOM   2583  H  HZ3  . TRP A 1 180 ? 28.353  -7.527  -12.194 1   26.903  ? 186  TRP A HZ3  1 c 
ATOM   2584  H  HH2  . TRP A 1 180 ? 26.607  -8.104  -10.769 1   27.176  ? 186  TRP A HH2  1 c 
ATOM   2585  N  N    . VAL A 1 181 ? 35.142  -5.609  -9.918  1   28.946  ? 187  VAL A N    1 ? 
ATOM   2586  C  CA   . VAL A 1 181 ? 36.296  -5.105  -10.644 1   32.931  ? 187  VAL A CA   1 ? 
ATOM   2587  C  C    . VAL A 1 181 ? 36.858  -6.205  -11.538 1   36.778  ? 187  VAL A C    1 ? 
ATOM   2588  O  O    . VAL A 1 181 ? 37.061  -5.982  -12.748 1   33.119  ? 187  VAL A O    1 ? 
ATOM   2589  C  CB   . VAL A 1 181 ? 37.414  -4.57   -9.734  1   33.75   ? 187  VAL A CB   1 ? 
ATOM   2590  C  CG1  . VAL A 1 181 ? 38.722  -4.322  -10.493 1   37.665  ? 187  VAL A CG1  1 ? 
ATOM   2591  C  CG2  . VAL A 1 181 ? 36.981  -3.314  -9.004  1   33.477  ? 187  VAL A CG2  1 ? 
ATOM   2592  H  H    . VAL A 1 181 ? 35.166  -5.567  -9.005  1   29.798  ? 187  VAL A H    1 c 
ATOM   2593  H  HA   . VAL A 1 181 ? 35.994  -4.373  -11.217 1   32.925  ? 187  VAL A HA   1 c 
ATOM   2594  H  HB   . VAL A 1 181 ? 37.591  -5.262  -9.056  1   34.215  ? 187  VAL A HB   1 c 
ATOM   2595  H  HG11 . VAL A 1 181 ? 38.541  -3.796  -11.289 1   36.429  ? 187  VAL A HG11 1 c 
ATOM   2596  H  HG12 . VAL A 1 181 ? 39.118  -5.172  -10.749 1   36.461  ? 187  VAL A HG12 1 c 
ATOM   2597  H  HG13 . VAL A 1 181 ? 39.341  -3.838  -9.921  1   36.445  ? 187  VAL A HG13 1 c 
ATOM   2598  H  HG21 . VAL A 1 181 ? 37.665  -3.059  -8.362  1   33.535  ? 187  VAL A HG21 1 c 
ATOM   2599  H  HG22 . VAL A 1 181 ? 36.146  -3.478  -8.538  1   33.462  ? 187  VAL A HG22 1 c 
ATOM   2600  H  HG23 . VAL A 1 181 ? 36.856  -2.593  -9.645  1   33.535  ? 187  VAL A HG23 1 c 
ATOM   2601  N  N    . TYR A 1 182 ? 37      -7.397  -10.944 1   33.643  ? 188  TYR A N    1 ? 
ATOM   2602  C  CA   . TYR A 1 182 ? 37.426  -8.572  -11.691 1   35.552  ? 188  TYR A CA   1 ? 
ATOM   2603  C  C    . TYR A 1 182 ? 36.427  -8.875  -12.797 1   35.019  ? 188  TYR A C    1 ? 
ATOM   2604  O  O    . TYR A 1 182 ? 36.828  -9.034  -13.946 1   37.784  ? 188  TYR A O    1 ? 
ATOM   2605  C  CB   . TYR A 1 182 ? 37.653  -9.765  -10.762 1   33.234  ? 188  TYR A CB   1 ? 
ATOM   2606  C  CG   . TYR A 1 182 ? 37.98   -11.066 -11.474 1   37.112  ? 188  TYR A CG   1 ? 
ATOM   2607  C  CD1  . TYR A 1 182 ? 36.949  -11.895 -11.919 1   43.814  ? 188  TYR A CD1  1 ? 
ATOM   2608  C  CD2  . TYR A 1 182 ? 39.284  -11.542 -11.592 1   36.153  ? 188  TYR A CD2  1 ? 
ATOM   2609  C  CE1  . TYR A 1 182 ? 37.215  -13.096 -12.557 1   45.499  ? 188  TYR A CE1  1 ? 
ATOM   2610  C  CE2  . TYR A 1 182 ? 39.562  -12.739 -12.25  1   38.447  ? 188  TYR A CE2  1 ? 
ATOM   2611  C  CZ   . TYR A 1 182 ? 38.521  -13.515 -12.727 1   38.625  ? 188  TYR A CZ   1 ? 
ATOM   2612  O  OH   . TYR A 1 182 ? 38.676  -14.714 -13.331 1   47.821  ? 188  TYR A OH   1 ? 
ATOM   2613  H  H    . TYR A 1 182 ? 36.834  -7.479  -10.049 1   34.728  ? 188  TYR A H    1 c 
ATOM   2614  H  HA   . TYR A 1 182 ? 38.296  -8.354  -12.12  1   34.662  ? 188  TYR A HA   1 c 
ATOM   2615  H  HB2  . TYR A 1 182 ? 38.389  -9.546  -10.15  1   34.61   ? 188  TYR A HB2  1 c 
ATOM   2616  H  HB3  . TYR A 1 182 ? 36.843  -9.895  -10.221 1   34.61   ? 188  TYR A HB3  1 c 
ATOM   2617  H  HD1  . TYR A 1 182 ? 36.054  -11.608 -11.831 1   42.367  ? 188  TYR A HD1  1 c 
ATOM   2618  H  HD2  . TYR A 1 182 ? 40      -11.002 -11.297 1   36.984  ? 188  TYR A HD2  1 c 
ATOM   2619  H  HE1  . TYR A 1 182 ? 36.506  -13.627 -12.879 1   43.31   ? 188  TYR A HE1  1 c 
ATOM   2620  H  HE2  . TYR A 1 182 ? 40.452  -13.029 -12.35  1   38.026  ? 188  TYR A HE2  1 c 
ATOM   2621  H  HH   . TYR A 1 182 ? 38.735  -14.589 -14.191 0   48.17   ? 188  TYR A HH   1 c 
ATOM   2622  N  N    . TYR A 1 183 ? 35.131  -8.93   -12.464 1   39.414  ? 189  TYR A N    1 ? 
ATOM   2623  C  CA   . TYR A 1 183 ? 34.112  -9.373  -13.414 1   34.026  ? 189  TYR A CA   1 ? 
ATOM   2624  C  C    . TYR A 1 183 ? 34.093  -8.453  -14.63  1   33.693  ? 189  TYR A C    1 ? 
ATOM   2625  O  O    . TYR A 1 183 ? 33.988  -8.893  -15.743 1   32.139  ? 189  TYR A O    1 ? 
ATOM   2626  C  CB   . TYR A 1 183 ? 32.717  -9.372  -12.782 1   36.335  ? 189  TYR A CB   1 ? 
ATOM   2627  C  CG   . TYR A 1 183 ? 31.59   -9.524  -13.789 1   36.093  ? 189  TYR A CG   1 ? 
ATOM   2628  C  CD1  . TYR A 1 183 ? 31.261  -10.759 -14.332 1   38.217  ? 189  TYR A CD1  1 ? 
ATOM   2629  C  CD2  . TYR A 1 183 ? 30.898  -8.411  -14.239 1   38.664  ? 189  TYR A CD2  1 ? 
ATOM   2630  C  CE1  . TYR A 1 183 ? 30.268  -10.885 -15.292 1   35.549  ? 189  TYR A CE1  1 ? 
ATOM   2631  C  CE2  . TYR A 1 183 ? 29.88   -8.528  -15.172 1   38.307  ? 189  TYR A CE2  1 ? 
ATOM   2632  C  CZ   . TYR A 1 183 ? 29.565  -9.765  -15.694 1   36.114  ? 189  TYR A CZ   1 ? 
ATOM   2633  O  OH   . TYR A 1 183 ? 28.537  -9.838  -16.588 1   38.959  ? 189  TYR A OH   1 ? 
ATOM   2634  H  H    . TYR A 1 183 ? 34.873  -8.691  -11.62  1   36.979  ? 189  TYR A H    1 c 
ATOM   2635  H  HA   . TYR A 1 183 ? 34.33   -10.297 -13.71  1   35.366  ? 189  TYR A HA   1 c 
ATOM   2636  H  HB2  . TYR A 1 183 ? 32.668  -10.11  -12.135 1   35.728  ? 189  TYR A HB2  1 c 
ATOM   2637  H  HB3  . TYR A 1 183 ? 32.595  -8.529  -12.292 1   35.776  ? 189  TYR A HB3  1 c 
ATOM   2638  H  HD1  . TYR A 1 183 ? 31.74   -11.527 -14.061 1   37.087  ? 189  TYR A HD1  1 c 
ATOM   2639  H  HD2  . TYR A 1 183 ? 31.104  -7.561  -13.884 1   37.924  ? 189  TYR A HD2  1 c 
ATOM   2640  H  HE1  . TYR A 1 183 ? 30.037  -11.734 -15.628 1   36.325  ? 189  TYR A HE1  1 c 
ATOM   2641  H  HE2  . TYR A 1 183 ? 29.402  -7.765  -15.449 1   37.849  ? 189  TYR A HE2  1 c 
ATOM   2642  H  HH   . TYR A 1 183 ? 27.816  -9.951  -16.18  0   39.25   ? 189  TYR A HH   1 c 
ATOM   2643  N  N    . PHE A 1 184 ? 34.16   -7.154  -14.413 1   36.681  ? 190  PHE A N    1 ? 
ATOM   2644  C  CA   . PHE A 1 184 ? 33.982  -6.233  -15.512 1   34.5    ? 190  PHE A CA   1 ? 
ATOM   2645  C  C    . PHE A 1 184 ? 35.265  -6.12   -16.336 1   39.083  ? 190  PHE A C    1 ? 
ATOM   2646  O  O    . PHE A 1 184 ? 35.176  -5.761  -17.505 1   32.563  ? 190  PHE A O    1 ? 
ATOM   2647  C  CB   . PHE A 1 184 ? 33.627  -4.838  -14.978 1   32.266  ? 190  PHE A CB   1 ? 
ATOM   2648  C  CG   . PHE A 1 184 ? 32.201  -4.636  -14.502 1   34.646  ? 190  PHE A CG   1 ? 
ATOM   2649  C  CD1  . PHE A 1 184 ? 31.136  -4.87   -15.359 1   33.626  ? 190  PHE A CD1  1 ? 
ATOM   2650  C  CD2  . PHE A 1 184 ? 31.926  -4.197  -13.207 1   32.774  ? 190  PHE A CD2  1 ? 
ATOM   2651  C  CE1  . PHE A 1 184 ? 29.84   -4.682  -14.935 1   36.146  ? 190  PHE A CE1  1 ? 
ATOM   2652  C  CE2  . PHE A 1 184 ? 30.624  -4.057  -12.777 1   34.796  ? 190  PHE A CE2  1 ? 
ATOM   2653  C  CZ   . PHE A 1 184 ? 29.576  -4.294  -13.65  1   33.737  ? 190  PHE A CZ   1 ? 
ATOM   2654  H  H    . PHE A 1 184 ? 34.314  -6.829  -13.572 1   35.429  ? 190  PHE A H    1 c 
ATOM   2655  H  HA   . PHE A 1 184 ? 33.245  -6.556  -16.096 1   35.25   ? 190  PHE A HA   1 c 
ATOM   2656  H  HB2  . PHE A 1 184 ? 34.235  -4.632  -14.234 1   33.319  ? 190  PHE A HB2  1 c 
ATOM   2657  H  HB3  . PHE A 1 184 ? 33.811  -4.184  -15.688 1   33.334  ? 190  PHE A HB3  1 c 
ATOM   2658  H  HD1  . PHE A 1 184 ? 31.303  -5.151  -16.245 1   34.415  ? 190  PHE A HD1  1 c 
ATOM   2659  H  HD2  . PHE A 1 184 ? 32.637  -4.052  -12.603 1   33.661  ? 190  PHE A HD2  1 c 
ATOM   2660  H  HE1  . PHE A 1 184 ? 29.126  -4.857  -15.527 1   34.946  ? 190  PHE A HE1  1 c 
ATOM   2661  H  HE2  . PHE A 1 184 ? 30.449  -3.763  -11.897 1   34.078  ? 190  PHE A HE2  1 c 
ATOM   2662  H  HZ   . PHE A 1 184 ? 28.685  -4.167  -13.367 1   34.515  ? 190  PHE A HZ   1 c 
ATOM   2663  N  N    . PHE A 1 185 ? 36.445  -6.233  -15.683 1   42.303  ? 191  PHE A N    1 ? 
ATOM   2664  C  CA   . PHE A 1 185 ? 37.678  -5.66   -16.221 1   35.359  ? 191  PHE A CA   1 ? 
ATOM   2665  C  C    . PHE A 1 185 ? 38.778  -6.705  -16.377 1   34.171  ? 191  PHE A C    1 ? 
ATOM   2666  O  O    . PHE A 1 185 ? 39.841  -6.363  -16.849 1   31.528  ? 191  PHE A O    1 ? 
ATOM   2667  C  CB   . PHE A 1 185 ? 38.233  -4.525  -15.367 1   32.21   ? 191  PHE A CB   1 ? 
ATOM   2668  C  CG   . PHE A 1 185 ? 37.28   -3.353  -15.16  1   33.224  ? 191  PHE A CG   1 ? 
ATOM   2669  C  CD1  . PHE A 1 185 ? 36.617  -2.754  -16.238 1   36.017  ? 191  PHE A CD1  1 ? 
ATOM   2670  C  CD2  . PHE A 1 185 ? 37.007  -2.883  -13.87  1   31.338  ? 191  PHE A CD2  1 ? 
ATOM   2671  C  CE1  . PHE A 1 185 ? 35.726  -1.69   -16.048 1   31.528  ? 191  PHE A CE1  1 ? 
ATOM   2672  C  CE2  . PHE A 1 185 ? 36.058  -1.872  -13.666 1   30.897  ? 191  PHE A CE2  1 ? 
ATOM   2673  C  CZ   . PHE A 1 185 ? 35.417  -1.279  -14.751 1   34.606  ? 191  PHE A CZ   1 ? 
ATOM   2674  H  H    . PHE A 1 185 ? 36.476  -6.667  -14.879 1   39.791  ? 191  PHE A H    1 c 
ATOM   2675  H  HA   . PHE A 1 185 ? 37.479  -5.293  -17.122 1   35.753  ? 191  PHE A HA   1 c 
ATOM   2676  H  HB2  . PHE A 1 185 ? 38.485  -4.889  -14.491 1   33.121  ? 191  PHE A HB2  1 c 
ATOM   2677  H  HB3  . PHE A 1 185 ? 39.052  -4.188  -15.793 1   33.13   ? 191  PHE A HB3  1 c 
ATOM   2678  H  HD1  . PHE A 1 185 ? 36.802  -3.05   -17.115 1   34.241  ? 191  PHE A HD1  1 c 
ATOM   2679  H  HD2  . PHE A 1 185 ? 37.403  -3.308  -13.128 1   31.754  ? 191  PHE A HD2  1 c 
ATOM   2680  H  HE1  . PHE A 1 185 ? 35.285  -1.303  -16.787 1   33.195  ? 191  PHE A HE1  1 c 
ATOM   2681  H  HE2  . PHE A 1 185 ? 35.887  -1.561  -12.792 1   31.867  ? 191  PHE A HE2  1 c 
ATOM   2682  H  HZ   . PHE A 1 185 ? 34.826  -0.556  -14.613 1   32.992  ? 191  PHE A HZ   1 c 
ATOM   2683  N  N    . HIS A 1 186 ? 38.527  -7.986  -16.082 1   35.614  ? 192  HIS A N    1 ? 
ATOM   2684  C  CA   . HIS A 1 186 ? 39.619  -8.942  -16.137 1   39.401  ? 192  HIS A CA   1 ? 
ATOM   2685  C  C    . HIS A 1 186 ? 40.181  -9.061  -17.556 1   44.045  ? 192  HIS A C    1 ? 
ATOM   2686  O  O    . HIS A 1 186 ? 41.393  -9.255  -17.703 1   41.141  ? 192  HIS A O    1 ? 
ATOM   2687  C  CB   . HIS A 1 186 ? 39.24   -10.305 -15.565 1   36.07   ? 192  HIS A CB   1 ? 
ATOM   2688  C  CG   . HIS A 1 186 ? 38.134  -10.995 -16.246 1   41.971  ? 192  HIS A CG   1 ? 
ATOM   2689  N  ND1  . HIS A 1 186 ? 36.819  -10.681 -15.97  1   46.68   ? 192  HIS A ND1  1 ? 
ATOM   2690  C  CD2  . HIS A 1 186 ? 38.114  -11.991 -17.163 1   43.7    ? 192  HIS A CD2  1 ? 
ATOM   2691  C  CE1  . HIS A 1 186 ? 36.03   -11.443 -16.715 1   46.863  ? 192  HIS A CE1  1 ? 
ATOM   2692  N  NE2  . HIS A 1 186 ? 36.796  -12.245 -17.455 1   45.803  ? 192  HIS A NE2  1 ? 
ATOM   2693  H  H    . HIS A 1 186 ? 37.688  -8.263  -15.851 1   36.234  ? 192  HIS A H    1 c 
ATOM   2694  H  HA   . HIS A 1 186 ? 40.336  -8.579  -15.561 1   38.728  ? 192  HIS A HA   1 c 
ATOM   2695  H  HB2  . HIS A 1 186 ? 40.033  -10.884 -15.593 1   38.138  ? 192  HIS A HB2  1 c 
ATOM   2696  H  HB3  . HIS A 1 186 ? 39.006  -10.191 -14.619 1   38.135  ? 192  HIS A HB3  1 c 
ATOM   2697  H  HD1  . HIS A 1 186 ? 36.463  -10.074 -15.385 0   46.1    ? 192  HIS A HD1  1 c 
ATOM   2698  H  HD2  . HIS A 1 186 ? 38.855  -12.414 -17.553 1   43.753  ? 192  HIS A HD2  1 c 
ATOM   2699  H  HE1  . HIS A 1 186 ? 35.088  -11.421 -16.717 1   46.505  ? 192  HIS A HE1  1 c 
ATOM   2700  H  HE2  . HIS A 1 186 ? 36.379  -12.719 -18.11  0   45.77   ? 192  HIS A HE2  1 c 
ATOM   2701  N  N    . ASP A 1 187 ? 39.306  -8.929  -18.568 1   43.772  ? 193  ASP A N    1 ? 
ATOM   2702  C  CA   . ASP A 1 187 ? 39.681  -9.061  -19.977 1   40.957  ? 193  ASP A CA   1 ? 
ATOM   2703  C  C    . ASP A 1 187 ? 40.577  -7.894  -20.371 1   40.041  ? 193  ASP A C    1 ? 
ATOM   2704  O  O    . ASP A 1 187 ? 41.537  -8.057  -21.104 1   41.917  ? 193  ASP A O    1 ? 
ATOM   2705  C  CB   . ASP A 1 187 ? 38.472  -9.261  -20.881 1   38.6    ? 193  ASP A CB   1 ? 
ATOM   2706  C  CG   . ASP A 1 187 ? 37.817  -10.645 -20.829 1   42.124  ? 193  ASP A CG   1 ? 
ATOM   2707  O  OD1  . ASP A 1 187 ? 38.503  -11.628 -20.532 1   55.333  ? 193  ASP A OD1  1 ? 
ATOM   2708  O  OD2  . ASP A 1 187 ? 36.595  -10.755 -21.026 1   52.218  ? 193  ASP A OD2  1 ? 
ATOM   2709  H  H    . ASP A 1 187 ? 38.43   -8.758  -18.371 1   42.99   ? 193  ASP A H    1 c 
ATOM   2710  H  HA   . ASP A 1 187 ? 40.217  -9.882  -20.062 1   40.948  ? 193  ASP A HA   1 c 
ATOM   2711  H  HB2  . ASP A 1 187 ? 37.792  -8.596  -20.645 1   39.934  ? 193  ASP A HB2  1 c 
ATOM   2712  H  HB3  . ASP A 1 187 ? 38.745  -9.093  -21.807 1   39.919  ? 193  ASP A HB3  1 c 
ATOM   2713  N  N    . SER A 1 188 ? 40.28   -6.703  -19.872 1   35.553  ? 194  SER A N    1 ? 
ATOM   2714  C  CA   . SER A 1 188 ? 41.107  -5.555  -20.146 1   38.432  ? 194  SER A CA   1 ? 
ATOM   2715  C  C    . SER A 1 188 ? 42.455  -5.686  -19.428 1   42.296  ? 194  SER A C    1 ? 
ATOM   2716  O  O    . SER A 1 188 ? 43.469  -5.191  -19.917 1   40.761  ? 194  SER A O    1 ? 
ATOM   2717  C  CB   . SER A 1 188 ? 40.426  -4.298  -19.731 1   40.125  ? 194  SER A CB   1 ? 
ATOM   2718  O  OG   . SER A 1 188 ? 39.29   -4.039  -20.526 1   41.277  ? 194  SER A OG   1 ? 
ATOM   2719  H  H    . SER A 1 188 ? 39.536  -6.6    -19.352 1   37.33   ? 194  SER A H    1 c 
ATOM   2720  H  HA   . SER A 1 188 ? 41.274  -5.515  -21.123 1   38.852  ? 194  SER A HA   1 c 
ATOM   2721  H  HB2  . SER A 1 188 ? 40.157  -4.371  -18.796 1   39.982  ? 194  SER A HB2  1 c 
ATOM   2722  H  HB3  . SER A 1 188 ? 41.052  -3.552  -19.809 1   40.006  ? 194  SER A HB3  1 c 
ATOM   2723  H  HG   . SER A 1 188 ? 38.922  -3.314  -20.253 0   40.92   ? 194  SER A HG   1 c 
ATOM   2724  N  N    . PHE A 1 189 ? 42.445  -6.272  -18.224 1   38.928  ? 195  PHE A N    1 ? 
ATOM   2725  C  CA   . PHE A 1 189 ? 43.645  -6.341  -17.403 1   38.511  ? 195  PHE A CA   1 ? 
ATOM   2726  C  C    . PHE A 1 189 ? 44.596  -7.324  -18.088 1   44.046  ? 195  PHE A C    1 ? 
ATOM   2727  O  O    . PHE A 1 189 ? 45.801  -7.092  -18.106 1   36.302  ? 195  PHE A O    1 ? 
ATOM   2728  C  CB   . PHE A 1 189 ? 43.404  -6.797  -15.95  1   30.945  ? 195  PHE A CB   1 ? 
ATOM   2729  C  CG   . PHE A 1 189 ? 42.698  -5.812  -15.008 1   27.891  ? 195  PHE A CG   1 ? 
ATOM   2730  C  CD1  . PHE A 1 189 ? 42.456  -4.491  -15.364 1   25.381  ? 195  PHE A CD1  1 ? 
ATOM   2731  C  CD2  . PHE A 1 189 ? 42.293  -6.228  -13.752 1   32.141  ? 195  PHE A CD2  1 ? 
ATOM   2732  C  CE1  . PHE A 1 189 ? 41.864  -3.607  -14.479 1   31.008  ? 195  PHE A CE1  1 ? 
ATOM   2733  C  CE2  . PHE A 1 189 ? 41.684  -5.357  -12.868 1   31.826  ? 195  PHE A CE2  1 ? 
ATOM   2734  C  CZ   . PHE A 1 189 ? 41.486  -4.039  -13.214 1   31.365  ? 195  PHE A CZ   1 ? 
ATOM   2735  H  H    . PHE A 1 189 ? 41.669  -6.63   -17.9   1   39.593  ? 195  PHE A H    1 c 
ATOM   2736  H  HA   . PHE A 1 189 ? 44.074  -5.444  -17.39  1   37.884  ? 195  PHE A HA   1 c 
ATOM   2737  H  HB2  . PHE A 1 189 ? 42.877  -7.625  -15.979 1   31.815  ? 195  PHE A HB2  1 c 
ATOM   2738  H  HB3  . PHE A 1 189 ? 44.275  -7.028  -15.557 1   31.831  ? 195  PHE A HB3  1 c 
ATOM   2739  H  HD1  . PHE A 1 189 ? 42.739  -4.178  -16.208 1   27.435  ? 195  PHE A HD1  1 c 
ATOM   2740  H  HD2  . PHE A 1 189 ? 42.451  -7.121  -13.489 1   30.994  ? 195  PHE A HD2  1 c 
ATOM   2741  H  HE1  . PHE A 1 189 ? 41.712  -2.712  -14.738 1   29.686  ? 195  PHE A HE1  1 c 
ATOM   2742  H  HE2  . PHE A 1 189 ? 41.424  -5.663  -12.013 1   31.723  ? 195  PHE A HE2  1 c 
ATOM   2743  H  HZ   . PHE A 1 189 ? 41.045  -3.452  -12.622 1   31.378  ? 195  PHE A HZ   1 c 
ATOM   2744  N  N    . ASP A 1 190 ? 44.009  -8.408  -18.62  1   39.706  ? 196  ASP A N    1 ? 
ATOM   2745  C  CA   . ASP A 1 190 ? 44.734  -9.489  -19.267 1   45.683  ? 196  ASP A CA   1 ? 
ATOM   2746  C  C    . ASP A 1 190 ? 45.485  -8.973  -20.505 1   44.455  ? 196  ASP A C    1 ? 
ATOM   2747  O  O    . ASP A 1 190 ? 46.576  -9.44   -20.806 1   40.706  ? 196  ASP A O    1 ? 
ATOM   2748  C  CB   . ASP A 1 190 ? 43.803  -10.626 -19.661 1   41.375  ? 196  ASP A CB   1 ? 
ATOM   2749  C  CG   . ASP A 1 190 ? 43.289  -11.53  -18.55  1   42.796  ? 196  ASP A CG   1 ? 
ATOM   2750  O  OD1  . ASP A 1 190 ? 43.761  -11.429 -17.38  1   39.505  ? 196  ASP A OD1  1 ? 
ATOM   2751  O  OD2  . ASP A 1 190 ? 42.404  -12.333 -18.867 1   41.258  ? 196  ASP A OD2  1 ? 
ATOM   2752  H  H    . ASP A 1 190 ? 43.1    -8.478  -18.565 1   41.966  ? 196  ASP A H    1 c 
ATOM   2753  H  HA   . ASP A 1 190 ? 45.393  -9.841  -18.629 1   43.355  ? 196  ASP A HA   1 c 
ATOM   2754  H  HB2  . ASP A 1 190 ? 43.025  -10.242 -20.116 1   42.651  ? 196  ASP A HB2  1 c 
ATOM   2755  H  HB3  . ASP A 1 190 ? 44.271  -11.195 -20.308 1   42.663  ? 196  ASP A HB3  1 c 
ATOM   2756  N  N    . LYS A 1 191 ? 44.909  -8.015  -21.229 1   40.766  ? 197  LYS A N    1 ? 
ATOM   2757  C  CA   . LYS A 1 191 ? 45.587  -7.431  -22.372 1   46.67   ? 197  LYS A CA   1 ? 
ATOM   2758  C  C    . LYS A 1 191 ? 46.867  -6.738  -21.923 1   52.68   ? 197  LYS A C    1 ? 
ATOM   2759  O  O    . LYS A 1 191 ? 47.778  -6.575  -22.736 1   57.468  ? 197  LYS A O    1 ? 
ATOM   2760  C  CB   . LYS A 1 191 ? 44.785  -6.374  -23.13  1   49.287  ? 197  LYS A CB   1 ? 
ATOM   2761  C  CG   . LYS A 1 191 ? 43.693  -6.903  -24.038 1   61.242  ? 197  LYS A CG   1 ? 
ATOM   2762  C  CD   . LYS A 1 191 ? 42.891  -5.768  -24.664 1   66.3    ? 197  LYS A CD   1 ? 
ATOM   2763  C  CE   . LYS A 1 191 ? 41.484  -6.152  -24.995 1   75.19   ? 197  LYS A CE   1 ? 
ATOM   2764  N  NZ   . LYS A 1 191 ? 40.58   -5.001  -24.857 1   78.795  ? 197  LYS A NZ   1 ? 
ATOM   2765  H  H    . LYS A 1 191 ? 44.07   -7.722  -21.013 1   42.899  ? 197  LYS A H    1 c 
ATOM   2766  H  HA   . LYS A 1 191 ? 45.825  -8.161  -22.999 1   46.887  ? 197  LYS A HA   1 c 
ATOM   2767  H  HB2  . LYS A 1 191 ? 44.375  -5.77   -22.475 1   51.289  ? 197  LYS A HB2  1 c 
ATOM   2768  H  HB3  . LYS A 1 191 ? 45.403  -5.842  -23.675 1   51.248  ? 197  LYS A HB3  1 c 
ATOM   2769  H  HG2  . LYS A 1 191 ? 44.102  -7.445  -24.747 1   59.347  ? 197  LYS A HG2  1 c 
ATOM   2770  H  HG3  . LYS A 1 191 ? 43.095  -7.479  -23.513 1   59.486  ? 197  LYS A HG3  1 c 
ATOM   2771  H  HD2  . LYS A 1 191 ? 42.876  -5.007  -24.044 1   66.939  ? 197  LYS A HD2  1 c 
ATOM   2772  H  HD3  . LYS A 1 191 ? 43.343  -5.476  -25.486 1   67.029  ? 197  LYS A HD3  1 c 
ATOM   2773  H  HE2  . LYS A 1 191 ? 41.442  -6.481  -25.911 1   73.828  ? 197  LYS A HE2  1 c 
ATOM   2774  H  HE3  . LYS A 1 191 ? 41.181  -6.862  -24.402 1   73.678  ? 197  LYS A HE3  1 c 
ATOM   2775  H  HZ1  . LYS A 1 191 ? 40.885  -4.31   -25.358 1   77.578  ? 197  LYS A HZ1  1 c 
ATOM   2776  H  HZ2  . LYS A 1 191 ? 40.538  -4.744  -23.99  1   77.571  ? 197  LYS A HZ2  1 c 
ATOM   2777  H  HZ3  . LYS A 1 191 ? 39.75   -5.229  -25.14  1   77.632  ? 197  LYS A HZ3  1 c 
ATOM   2778  N  N    . ILE A 1 192 ? 46.918  -6.28   -20.665 1   43.578  ? 198  ILE A N    1 ? 
ATOM   2779  C  CA   . ILE A 1 192 ? 48.094  -5.565  -20.192 1   41.881  ? 198  ILE A CA   1 ? 
ATOM   2780  C  C    . ILE A 1 192 ? 49.065  -6.522  -19.508 1   40.518  ? 198  ILE A C    1 ? 
ATOM   2781  O  O    . ILE A 1 192 ? 50.243  -6.505  -19.821 1   41.908  ? 198  ILE A O    1 ? 
ATOM   2782  C  CB   . ILE A 1 192 ? 47.663  -4.362  -19.355 1   41.9    ? 198  ILE A CB   1 ? 
ATOM   2783  C  CG1  . ILE A 1 192 ? 46.941  -3.373  -20.304 1   50.814  ? 198  ILE A CG1  1 ? 
ATOM   2784  C  CG2  . ILE A 1 192 ? 48.842  -3.695  -18.653 1   35.937  ? 198  ILE A CG2  1 ? 
ATOM   2785  C  CD1  . ILE A 1 192 ? 46.129  -2.308  -19.608 1   51.916  ? 198  ILE A CD1  1 ? 
ATOM   2786  H  H    . ILE A 1 192 ? 46.209  -6.392  -20.101 1   45.135  ? 198  ILE A H    1 c 
ATOM   2787  H  HA   . ILE A 1 192 ? 48.552  -5.21   -20.979 1   42.13   ? 198  ILE A HA   1 c 
ATOM   2788  H  HB   . ILE A 1 192 ? 47.025  -4.666  -18.679 1   42.2    ? 198  ILE A HB   1 c 
ATOM   2789  H  HG12 . ILE A 1 192 ? 47.613  -2.935  -20.866 1   48.89   ? 198  ILE A HG12 1 c 
ATOM   2790  H  HG13 . ILE A 1 192 ? 46.347  -3.879  -20.894 1   48.831  ? 198  ILE A HG13 1 c 
ATOM   2791  H  HG21 . ILE A 1 192 ? 48.544  -2.878  -18.219 1   37.746  ? 198  ILE A HG21 1 c 
ATOM   2792  H  HG22 . ILE A 1 192 ? 49.531  -3.481  -19.304 1   37.635  ? 198  ILE A HG22 1 c 
ATOM   2793  H  HG23 . ILE A 1 192 ? 49.208  -4.297  -17.983 1   37.646  ? 198  ILE A HG23 1 c 
ATOM   2794  H  HD11 . ILE A 1 192 ? 45.46   -2.73   -19.036 1   51.558  ? 198  ILE A HD11 1 c 
ATOM   2795  H  HD12 . ILE A 1 192 ? 45.682  -1.752  -20.273 1   51.558  ? 198  ILE A HD12 1 c 
ATOM   2796  H  HD13 . ILE A 1 192 ? 46.716  -1.75   -19.062 1   51.468  ? 198  ILE A HD13 1 c 
ATOM   2797  N  N    . ASP A 1 193 ? 48.568  -7.394  -18.625 1   36.834  ? 199  ASP A N    1 ? 
ATOM   2798  C  CA   . ASP A 1 193 ? 49.391  -8.468  -18.099 1   38.206  ? 199  ASP A CA   1 ? 
ATOM   2799  C  C    . ASP A 1 193 ? 48.486  -9.467  -17.384 1   37.781  ? 199  ASP A C    1 ? 
ATOM   2800  O  O    . ASP A 1 193 ? 47.885  -9.142  -16.372 1   44.376  ? 199  ASP A O    1 ? 
ATOM   2801  C  CB   . ASP A 1 193 ? 50.507  -7.914  -17.212 1   32.085  ? 199  ASP A CB   1 ? 
ATOM   2802  C  CG   . ASP A 1 193 ? 51.512  -8.945  -16.726 1   32.334  ? 199  ASP A CG   1 ? 
ATOM   2803  O  OD1  . ASP A 1 193 ? 51.094  -10.104 -16.513 1   35.879  ? 199  ASP A OD1  1 ? 
ATOM   2804  O  OD2  . ASP A 1 193 ? 52.684  -8.566  -16.505 1   36.916  ? 199  ASP A OD2  1 ? 
ATOM   2805  H  H    . ASP A 1 193 ? 47.703  -7.313  -18.341 1   38.047  ? 199  ASP A H    1 c 
ATOM   2806  H  HA   . ASP A 1 193 ? 49.825  -8.918  -18.856 1   36.771  ? 199  ASP A HA   1 c 
ATOM   2807  H  HB2  . ASP A 1 193 ? 51.004  -7.221  -17.692 1   33.53   ? 199  ASP A HB2  1 c 
ATOM   2808  H  HB3  . ASP A 1 193 ? 50.099  -7.496  -16.424 1   33.461  ? 199  ASP A HB3  1 c 
ATOM   2809  N  N    . PRO A 1 194 ? 48.373  -10.723 -17.848 1   39.395  ? 200  PRO A N    1 ? 
ATOM   2810  C  CA   . PRO A 1 194 ? 47.489  -11.679 -17.198 1   38.982  ? 200  PRO A CA   1 ? 
ATOM   2811  C  C    . PRO A 1 194 ? 47.67   -11.919 -15.704 1   36.806  ? 200  PRO A C    1 ? 
ATOM   2812  O  O    . PRO A 1 194 ? 46.793  -12.533 -15.085 1   34.314  ? 200  PRO A O    1 ? 
ATOM   2813  C  CB   . PRO A 1 194 ? 47.74   -12.979 -17.984 1   40.079  ? 200  PRO A CB   1 ? 
ATOM   2814  C  CG   . PRO A 1 194 ? 48.252  -12.532 -19.344 1   41.868  ? 200  PRO A CG   1 ? 
ATOM   2815  C  CD   . PRO A 1 194 ? 49.003  -11.256 -19.07  1   42.784  ? 200  PRO A CD   1 ? 
ATOM   2816  H  HA   . PRO A 1 194 ? 46.559  -11.386 -17.362 1   38.879  ? 200  PRO A HA   1 c 
ATOM   2817  H  HB2  . PRO A 1 194 ? 48.408  -13.541 -17.527 1   40.207  ? 200  PRO A HB2  1 c 
ATOM   2818  H  HB3  . PRO A 1 194 ? 46.906  -13.496 -18.078 1   40.223  ? 200  PRO A HB3  1 c 
ATOM   2819  H  HG2  . PRO A 1 194 ? 48.845  -13.208 -19.733 1   41.664  ? 200  PRO A HG2  1 c 
ATOM   2820  H  HG3  . PRO A 1 194 ? 47.508  -12.371 -19.961 1   41.664  ? 200  PRO A HG3  1 c 
ATOM   2821  H  HD2  . PRO A 1 194 ? 49.958  -11.436 -18.924 1   41.76   ? 200  PRO A HD2  1 c 
ATOM   2822  H  HD3  . PRO A 1 194 ? 48.906  -10.629 -19.82  1   41.712  ? 200  PRO A HD3  1 c 
ATOM   2823  N  N    . VAL A 1 195 ? 48.834  -11.552 -15.149 1   33.562  ? 201  VAL A N    1 ? 
ATOM   2824  C  CA   . VAL A 1 195 ? 49.073  -11.827 -13.739 1   35.944  ? 201  VAL A CA   1 ? 
ATOM   2825  C  C    . VAL A 1 195 ? 48.167  -10.977 -12.841 1   29.873  ? 201  VAL A C    1 ? 
ATOM   2826  O  O    . VAL A 1 195 ? 47.814  -11.399 -11.747 1   33.707  ? 201  VAL A O    1 ? 
ATOM   2827  C  CB   . VAL A 1 195 ? 50.545  -11.714 -13.309 1   39.084  ? 201  VAL A CB   1 ? 
ATOM   2828  C  CG1  . VAL A 1 195 ? 51.021  -10.267 -13.125 1   36.806  ? 201  VAL A CG1  1 ? 
ATOM   2829  C  CG2  . VAL A 1 195 ? 50.75   -12.52  -12.04  1   33.562  ? 201  VAL A CG2  1 ? 
ATOM   2830  H  H    . VAL A 1 195 ? 49.486  -11.147 -15.645 1   34.913  ? 201  VAL A H    1 c 
ATOM   2831  H  HA   . VAL A 1 195 ? 48.814  -12.758 -13.594 1   34.808  ? 201  VAL A HA   1 c 
ATOM   2832  H  HB   . VAL A 1 195 ? 51.089  -12.124 -14.021 1   36.985  ? 201  VAL A HB   1 c 
ATOM   2833  H  HG11 . VAL A 1 195 ? 50.63   -9.894  -12.316 1   37.411  ? 201  VAL A HG11 1 c 
ATOM   2834  H  HG12 . VAL A 1 195 ? 50.747  -9.735  -13.891 1   37.439  ? 201  VAL A HG12 1 c 
ATOM   2835  H  HG13 . VAL A 1 195 ? 51.99   -10.251 -13.051 1   37.446  ? 201  VAL A HG13 1 c 
ATOM   2836  H  HG21 . VAL A 1 195 ? 51.674  -12.44  -11.753 1   35.101  ? 201  VAL A HG21 1 c 
ATOM   2837  H  HG22 . VAL A 1 195 ? 50.545  -13.455 -12.211 1   35.098  ? 201  VAL A HG22 1 c 
ATOM   2838  H  HG23 . VAL A 1 195 ? 50.167  -12.184 -11.34  1   35.071  ? 201  VAL A HG23 1 c 
ATOM   2839  N  N    . ILE A 1 196 ? 47.722  -9.819  -13.321 1   29.693  ? 202  ILE A N    1 ? 
ATOM   2840  C  CA   . ILE A 1 196 ? 46.887  -8.929  -12.516 1   32.518  ? 202  ILE A CA   1 ? 
ATOM   2841  C  C    . ILE A 1 196 ? 45.6    -9.627  -12.097 1   31.845  ? 202  ILE A C    1 ? 
ATOM   2842  O  O    . ILE A 1 196 ? 45.35   -9.844  -10.911 1   35.431  ? 202  ILE A O    1 ? 
ATOM   2843  C  CB   . ILE A 1 196 ? 46.599  -7.629  -13.27  1   35.599  ? 202  ILE A CB   1 ? 
ATOM   2844  C  CG1  . ILE A 1 196 ? 47.888  -6.953  -13.693 1   32.984  ? 202  ILE A CG1  1 ? 
ATOM   2845  C  CG2  . ILE A 1 196 ? 45.738  -6.714  -12.39  1   35.953  ? 202  ILE A CG2  1 ? 
ATOM   2846  C  CD1  . ILE A 1 196 ? 47.76   -5.994  -14.857 1   36.065  ? 202  ILE A CD1  1 ? 
ATOM   2847  H  H    . ILE A 1 196 ? 47.928  -9.578  -14.177 1   30.518  ? 202  ILE A H    1 c 
ATOM   2848  H  HA   . ILE A 1 196 ? 47.385  -8.702  -11.707 1   32.379  ? 202  ILE A HA   1 c 
ATOM   2849  H  HB   . ILE A 1 196 ? 46.091  -7.848  -14.076 1   34.618  ? 202  ILE A HB   1 c 
ATOM   2850  H  HG12 . ILE A 1 196 ? 48.244  -6.461  -12.925 1   34.257  ? 202  ILE A HG12 1 c 
ATOM   2851  H  HG13 . ILE A 1 196 ? 48.543  -7.639  -13.93  1   34.188  ? 202  ILE A HG13 1 c 
ATOM   2852  H  HG21 . ILE A 1 196 ? 45.688  -5.83   -12.791 1   35.844  ? 202  ILE A HG21 1 c 
ATOM   2853  H  HG22 . ILE A 1 196 ? 46.136  -6.644  -11.505 1   35.844  ? 202  ILE A HG22 1 c 
ATOM   2854  H  HG23 . ILE A 1 196 ? 44.841  -7.082  -12.312 1   35.826  ? 202  ILE A HG23 1 c 
ATOM   2855  H  HD11 . ILE A 1 196 ? 47.434  -6.474  -15.642 1   35.121  ? 202  ILE A HD11 1 c 
ATOM   2856  H  HD12 . ILE A 1 196 ? 48.631  -5.602  -15.057 1   35.121  ? 202  ILE A HD12 1 c 
ATOM   2857  H  HD13 . ILE A 1 196 ? 47.13   -5.284  -14.629 1   35.109  ? 202  ILE A HD13 1 c 
ATOM   2858  N  N    . SER A 1 197 ? 44.826  -10.049 -13.099 1   38.341  ? 203  SER A N    1 ? 
ATOM   2859  C  CA   . SER A 1 197 ? 43.597  -10.781 -12.886 1   34.393  ? 203  SER A CA   1 ? 
ATOM   2860  C  C    . SER A 1 197 ? 43.873  -12.067 -12.156 1   33.683  ? 203  SER A C    1 ? 
ATOM   2861  O  O    . SER A 1 197 ? 43.058  -12.497 -11.349 1   41.982  ? 203  SER A O    1 ? 
ATOM   2862  C  CB   . SER A 1 197 ? 42.896  -11.094 -14.176 1   36.461  ? 203  SER A CB   1 ? 
ATOM   2863  O  OG   . SER A 1 197 ? 42.488  -9.895  -14.785 1   39.221  ? 203  SER A OG   1 ? 
ATOM   2864  H  H    . SER A 1 197 ? 45.083  -9.876  -13.959 1   35.722  ? 203  SER A H    1 c 
ATOM   2865  H  HA   . SER A 1 197 ? 42.997  -10.226 -12.326 1   35.37   ? 203  SER A HA   1 c 
ATOM   2866  H  HB2  . SER A 1 197 ? 43.502  -11.576 -14.77  1   36.622  ? 203  SER A HB2  1 c 
ATOM   2867  H  HB3  . SER A 1 197 ? 42.117  -11.655 -14     1   36.597  ? 203  SER A HB3  1 c 
ATOM   2868  H  HG   . SER A 1 197 ? 42.091  -10.088 -15.498 0   37.43   ? 203  SER A HG   1 c 
ATOM   2869  N  N    . GLN A 1 198 ? 44.96   -12.723 -12.555 1   34.203  ? 204  GLN A N    1 ? 
ATOM   2870  C  CA   . GLN A 1 198 ? 45.213  -14.06  -12.047 1   37.007  ? 204  GLN A CA   1 ? 
ATOM   2871  C  C    . GLN A 1 198 ? 45.378  -13.97  -10.54  1   30.773  ? 204  GLN A C    1 ? 
ATOM   2872  O  O    . GLN A 1 198 ? 44.795  -14.771 -9.798  1   29.776  ? 204  GLN A O    1 ? 
ATOM   2873  C  CB   . GLN A 1 198 ? 46.396  -14.787 -12.697 1   39.293  ? 204  GLN A CB   1 ? 
ATOM   2874  C  CG   . GLN A 1 198 ? 46.354  -16.291 -12.449 1   44.882  ? 204  GLN A CG   1 ? 
ATOM   2875  C  CD   . GLN A 1 198 ? 47.017  -16.788 -11.172 1   44.212  ? 204  GLN A CD   1 ? 
ATOM   2876  O  OE1  . GLN A 1 198 ? 46.993  -17.99  -10.876 1   45.283  ? 204  GLN A OE1  1 ? 
ATOM   2877  N  NE2  . GLN A 1 198 ? 47.67   -15.915 -10.427 1   39.143  ? 204  GLN A NE2  1 ? 
ATOM   2878  H  H    . GLN A 1 198 ? 45.544  -12.348 -13.149 1   34.695  ? 204  GLN A H    1 c 
ATOM   2879  H  HA   . GLN A 1 198 ? 44.405  -14.604 -12.228 1   35.684  ? 204  GLN A HA   1 c 
ATOM   2880  H  HB2  . GLN A 1 198 ? 46.377  -14.622 -13.662 1   39.911  ? 204  GLN A HB2  1 c 
ATOM   2881  H  HB3  . GLN A 1 198 ? 47.233  -14.419 -12.347 1   39.891  ? 204  GLN A HB3  1 c 
ATOM   2882  H  HG2  . GLN A 1 198 ? 45.418  -16.583 -12.435 1   43.295  ? 204  GLN A HG2  1 c 
ATOM   2883  H  HG3  . GLN A 1 198 ? 46.786  -16.744 -13.205 1   43.374  ? 204  GLN A HG3  1 c 
ATOM   2884  H  HE21 . GLN A 1 198 ? 47.41   -15.763 -9.59   1   40.574  ? 204  GLN A HE21 1 c 
ATOM   2885  H  HE22 . GLN A 1 198 ? 48.368  -15.488 -10.771 1   40.609  ? 204  GLN A HE22 1 c 
ATOM   2886  N  N    . ARG A 1 199 ? 46.15   -12.968 -10.111 1   31.492  ? 205  ARG A N    1 ? 
ATOM   2887  C  CA   . ARG A 1 199 ? 46.436  -12.797 -8.697  1   33.179  ? 205  ARG A CA   1 ? 
ATOM   2888  C  C    . ARG A 1 199 ? 45.219  -12.298 -7.911  1   33.823  ? 205  ARG A C    1 ? 
ATOM   2889  O  O    . ARG A 1 199 ? 44.998  -12.699 -6.759  1   32.56   ? 205  ARG A O    1 ? 
ATOM   2890  C  CB   . ARG A 1 199 ? 47.555  -11.768 -8.533  1   34.235  ? 205  ARG A CB   1 ? 
ATOM   2891  C  CG   . ARG A 1 199 ? 48.037  -11.625 -7.103  1   32.363  ? 205  ARG A CG   1 ? 
ATOM   2892  C  CD   . ARG A 1 199 ? 49.116  -10.564 -7.06   1   32.409  ? 205  ARG A CD   1 ? 
ATOM   2893  N  NE   . ARG A 1 199 ? 49.825  -10.51  -5.778  1   33.724  ? 205  ARG A NE   1 ? 
ATOM   2894  C  CZ   . ARG A 1 199 ? 50.762  -9.623  -5.505  1   28.315  ? 205  ARG A CZ   1 ? 
ATOM   2895  N  NH1  . ARG A 1 199 ? 51.23   -8.803  -6.41   1   29.09   ? 205  ARG A NH1  1 ? 
ATOM   2896  N  NH2  . ARG A 1 199 ? 51.221  -9.573  -4.315  1   29.233  ? 205  ARG A NH2  1 ? 
ATOM   2897  H  H    . ARG A 1 199 ? 46.513  -12.382 -10.711 1   31.758  ? 205  ARG A H    1 c 
ATOM   2898  H  HA   . ARG A 1 199 ? 46.73   -13.667 -8.324  1   33.114  ? 205  ARG A HA   1 c 
ATOM   2899  H  HB2  . ARG A 1 199 ? 48.312  -12.032 -9.099  1   33.552  ? 205  ARG A HB2  1 c 
ATOM   2900  H  HB3  . ARG A 1 199 ? 47.234  -10.897 -8.849  1   33.558  ? 205  ARG A HB3  1 c 
ATOM   2901  H  HG2  . ARG A 1 199 ? 47.293  -11.356 -6.521  1   32.792  ? 205  ARG A HG2  1 c 
ATOM   2902  H  HG3  . ARG A 1 199 ? 48.403  -12.479 -6.786  1   32.789  ? 205  ARG A HG3  1 c 
ATOM   2903  H  HD2  . ARG A 1 199 ? 49.762  -10.743 -7.774  1   32.685  ? 205  ARG A HD2  1 c 
ATOM   2904  H  HD3  . ARG A 1 199 ? 48.709  -9.692  -7.238  1   32.676  ? 205  ARG A HD3  1 c 
ATOM   2905  H  HE   . ARG A 1 199 ? 49.615  -11.096 -5.168  1   32.011  ? 205  ARG A HE   1 c 
ATOM   2906  H  HH11 . ARG A 1 199 ? 50.941  -8.842  -7.244  1   28.964  ? 205  ARG A HH11 1 c 
ATOM   2907  H  HH12 . ARG A 1 199 ? 51.84   -8.203  -6.188  1   28.879  ? 205  ARG A HH12 1 c 
ATOM   2908  H  HH21 . ARG A 1 199 ? 50.88   -10.091 -3.685  1   29.01   ? 205  ARG A HH21 1 c 
ATOM   2909  H  HH22 . ARG A 1 199 ? 51.882  -9.019  -4.119  1   28.962  ? 205  ARG A HH22 1 c 
ATOM   2910  N  N    . LEU A 1 200 ? 44.461  -11.38  -8.511  1   29.958  ? 206  LEU A N    1 ? 
ATOM   2911  C  CA   . LEU A 1 200 ? 43.281  -10.859 -7.846  1   27.415  ? 206  LEU A CA   1 ? 
ATOM   2912  C  C    . LEU A 1 200 ? 42.303  -11.998 -7.554  1   29.675  ? 206  LEU A C    1 ? 
ATOM   2913  O  O    . LEU A 1 200 ? 41.804  -12.111 -6.445  1   27.844  ? 206  LEU A O    1 ? 
ATOM   2914  C  CB   . LEU A 1 200 ? 42.673  -9.785  -8.733  1   29.582  ? 206  LEU A CB   1 ? 
ATOM   2915  C  CG   . LEU A 1 200 ? 41.451  -9.064  -8.15   1   32.601  ? 206  LEU A CG   1 ? 
ATOM   2916  C  CD1  . LEU A 1 200 ? 41.723  -8.598  -6.743  1   29.372  ? 206  LEU A CD1  1 ? 
ATOM   2917  C  CD2  . LEU A 1 200 ? 40.952  -7.94   -9.041  1   34.392  ? 206  LEU A CD2  1 ? 
ATOM   2918  H  H    . LEU A 1 200 ? 44.682  -11.069 -9.341  1   30.248  ? 206  LEU A H    1 c 
ATOM   2919  H  HA   . LEU A 1 200 ? 43.562  -10.457 -6.989  1   28.773  ? 206  LEU A HA   1 c 
ATOM   2920  H  HB2  . LEU A 1 200 ? 43.368  -9.114  -8.925  1   29.72   ? 206  LEU A HB2  1 c 
ATOM   2921  H  HB3  . LEU A 1 200 ? 42.411  -10.201 -9.587  1   29.717  ? 206  LEU A HB3  1 c 
ATOM   2922  H  HG   . LEU A 1 200 ? 40.717  -9.728  -8.093  1   31.704  ? 206  LEU A HG   1 c 
ATOM   2923  H  HD11 . LEU A 1 200 ? 41.737  -9.362  -6.142  1   30.284  ? 206  LEU A HD11 1 c 
ATOM   2924  H  HD12 . LEU A 1 200 ? 41.024  -7.983  -6.465  1   30.337  ? 206  LEU A HD12 1 c 
ATOM   2925  H  HD13 . LEU A 1 200 ? 42.582  -8.145  -6.711  1   30.317  ? 206  LEU A HD13 1 c 
ATOM   2926  H  HD21 . LEU A 1 200 ? 40.692  -8.301  -9.906  1   33.852  ? 206  LEU A HD21 1 c 
ATOM   2927  H  HD22 . LEU A 1 200 ? 41.658  -7.284  -9.165  1   33.866  ? 206  LEU A HD22 1 c 
ATOM   2928  H  HD23 . LEU A 1 200 ? 40.184  -7.512  -8.627  1   33.832  ? 206  LEU A HD23 1 c 
ATOM   2929  N  N    . ARG A 1 201 ? 42.047  -12.846 -8.556  1   32.329  ? 207  ARG A N    1 ? 
ATOM   2930  C  CA   . ARG A 1 201 ? 41.212  -14.028 -8.377  1   35.092  ? 207  ARG A CA   1 ? 
ATOM   2931  C  C    . ARG A 1 201 ? 41.747  -14.918 -7.252  1   38.421  ? 207  ARG A C    1 ? 
ATOM   2932  O  O    . ARG A 1 201 ? 40.985  -15.421 -6.422  1   37.654  ? 207  ARG A O    1 ? 
ATOM   2933  C  CB   . ARG A 1 201 ? 41.112  -14.736 -9.733  1   35.249  ? 207  ARG A CB   1 ? 
ATOM   2934  C  CG   . ARG A 1 201 ? 40.219  -15.973 -9.791  1   37.431  ? 207  ARG A CG   1 ? 
ATOM   2935  C  CD   . ARG A 1 201 ? 38.858  -15.758 -9.133  1   41.247  ? 207  ARG A CD   1 ? 
ATOM   2936  N  NE   . ARG A 1 201 ? 38.029  -16.967 -9.183  1   36.338  ? 207  ARG A NE   1 ? 
ATOM   2937  C  CZ   . ARG A 1 201 ? 37.81   -17.875 -8.22   1   38.167  ? 207  ARG A CZ   1 ? 
ATOM   2938  N  NH1  . ARG A 1 201 ? 38.521  -17.91  -7.106  1   43.091  ? 207  ARG A NH1  1 ? 
ATOM   2939  N  NH2  . ARG A 1 201 ? 36.846  -18.773 -8.374  1   39.321  ? 207  ARG A NH2  1 ? 
ATOM   2940  H  H    . ARG A 1 201 ? 42.402  -12.68  -9.382  1   32.26   ? 207  ARG A H    1 c 
ATOM   2941  H  HA   . ARG A 1 201 ? 40.307  -13.718 -8.121  1   35.195  ? 207  ARG A HA   1 c 
ATOM   2942  H  HB2  . ARG A 1 201 ? 40.782  -14.088 -10.389 1   35.711  ? 207  ARG A HB2  1 c 
ATOM   2943  H  HB3  . ARG A 1 201 ? 42.017  -14.995 -10.01  1   35.723  ? 207  ARG A HB3  1 c 
ATOM   2944  H  HG2  . ARG A 1 201 ? 40.082  -16.228 -10.729 1   37.749  ? 207  ARG A HG2  1 c 
ATOM   2945  H  HG3  . ARG A 1 201 ? 40.674  -16.719 -9.342  1   37.749  ? 207  ARG A HG3  1 c 
ATOM   2946  H  HD2  . ARG A 1 201 ? 38.983  -15.497 -8.199  1   39.139  ? 207  ARG A HD2  1 c 
ATOM   2947  H  HD3  . ARG A 1 201 ? 38.391  -15.029 -9.59   1   39.161  ? 207  ARG A HD3  1 c 
ATOM   2948  H  HE   . ARG A 1 201 ? 37.625  -17.12  -9.939  1   37.889  ? 207  ARG A HE   1 c 
ATOM   2949  H  HH11 . ARG A 1 201 ? 39.362  -17.635 -7.114  1   41.424  ? 207  ARG A HH11 1 c 
ATOM   2950  H  HH12 . ARG A 1 201 ? 38.152  -18.206 -6.358  1   41.394  ? 207  ARG A HH12 1 c 
ATOM   2951  H  HH21 . ARG A 1 201 ? 36.313  -18.735 -9.078  1   38.952  ? 207  ARG A HH21 1 c 
ATOM   2952  H  HH22 . ARG A 1 201 ? 36.737  -19.41  -7.77   1   39.007  ? 207  ARG A HH22 1 c 
ATOM   2953  N  N    . HIS A 1 202 ? 43.076  -15.096 -7.204  1   45.396  ? 208  HIS A N    1 ? 
ATOM   2954  C  CA   . HIS A 1 202 ? 43.667  -15.999 -6.227  1   36.535  ? 208  HIS A CA   1 ? 
ATOM   2955  C  C    . HIS A 1 202 ? 43.498  -15.397 -4.842  1   34.312  ? 208  HIS A C    1 ? 
ATOM   2956  O  O    . HIS A 1 202 ? 43.099  -16.132 -3.936  1   27.461  ? 208  HIS A O    1 ? 
ATOM   2957  C  CB   . HIS A 1 202 ? 45.122  -16.344 -6.553  1   40.013  ? 208  HIS A CB   1 ? 
ATOM   2958  C  CG   . HIS A 1 202 ? 45.823  -17.024 -5.419  1   44.469  ? 208  HIS A CG   1 ? 
ATOM   2959  N  ND1  . HIS A 1 202 ? 45.828  -18.392 -5.209  1   46.203  ? 208  HIS A ND1  1 ? 
ATOM   2960  C  CD2  . HIS A 1 202 ? 46.534  -16.479 -4.404  1   47.667  ? 208  HIS A CD2  1 ? 
ATOM   2961  C  CE1  . HIS A 1 202 ? 46.522  -18.658 -4.104  1   49.011  ? 208  HIS A CE1  1 ? 
ATOM   2962  N  NE2  . HIS A 1 202 ? 46.944  -17.511 -3.582  1   49.699  ? 208  HIS A NE2  1 ? 
ATOM   2963  H  H    . HIS A 1 202 ? 43.621  -14.659 -7.793  1   41.367  ? 208  HIS A H    1 c 
ATOM   2964  H  HA   . HIS A 1 202 ? 43.149  -16.841 -6.258  1   38.23   ? 208  HIS A HA   1 c 
ATOM   2965  H  HB2  . HIS A 1 202 ? 45.144  -16.923 -7.342  1   40.24   ? 208  HIS A HB2  1 c 
ATOM   2966  H  HB3  . HIS A 1 202 ? 45.601  -15.515 -6.774  1   40.192  ? 208  HIS A HB3  1 c 
ATOM   2967  H  HD1  . HIS A 1 202 ? 45.494  -18.985 -5.746  0   46.46   ? 208  HIS A HD1  1 c 
ATOM   2968  H  HD2  . HIS A 1 202 ? 46.696  -15.567 -4.259  1   47.321  ? 208  HIS A HD2  1 c 
ATOM   2969  H  HE1  . HIS A 1 202 ? 46.675  -19.516 -3.747  1   48.456  ? 208  HIS A HE1  1 c 
ATOM   2970  H  HE2  . HIS A 1 202 ? 47.384  -17.426 -2.808  0   50.84   ? 208  HIS A HE2  1 c 
ATOM   2971  N  N    . THR A 1 203 ? 43.746  -14.074 -4.716  1   31.288  ? 209  THR A N    1 ? 
ATOM   2972  C  CA   . THR A 1 203 ? 43.496  -13.321 -3.487  1   36.632  ? 209  THR A CA   1 ? 
ATOM   2973  C  C    . THR A 1 203 ? 42.029  -13.383 -3.002  1   36.575  ? 209  THR A C    1 ? 
ATOM   2974  O  O    . THR A 1 203 ? 41.78   -13.627 -1.821  1   35.307  ? 209  THR A O    1 ? 
ATOM   2975  C  CB   . THR A 1 203 ? 43.981  -11.878 -3.647  1   37.488  ? 209  THR A CB   1 ? 
ATOM   2976  O  OG1  . THR A 1 203 ? 45.38   -11.912 -3.945  1   33.853  ? 209  THR A OG1  1 ? 
ATOM   2977  C  CG2  . THR A 1 203 ? 43.8    -11.059 -2.379  1   34.229  ? 209  THR A CG2  1 ? 
ATOM   2978  H  H    . THR A 1 203 ? 44.094  -13.626 -5.433  1   33.262  ? 209  THR A H    1 c 
ATOM   2979  H  HA   . THR A 1 203 ? 44.049  -13.733 -2.787  1   35.665  ? 209  THR A HA   1 c 
ATOM   2980  H  HB   . THR A 1 203 ? 43.497  -11.444 -4.39   1   35.99   ? 209  THR A HB   1 c 
ATOM   2981  H  HG1  . THR A 1 203 ? 45.805  -12.321 -3.309  0   33.62   ? 209  THR A HG1  1 c 
ATOM   2982  H  HG21 . THR A 1 203 ? 44.237  -10.197 -2.485  1   35.153  ? 209  THR A HG21 1 c 
ATOM   2983  H  HG22 . THR A 1 203 ? 44.196  -11.531 -1.628  1   35.142  ? 209  THR A HG22 1 c 
ATOM   2984  H  HG23 . THR A 1 203 ? 42.852  -10.921 -2.212  1   35.141  ? 209  THR A HG23 1 c 
ATOM   2985  N  N    . LEU A 1 204 ? 41.052  -13.092 -3.856  1   35.915  ? 210  LEU A N    1 ? 
ATOM   2986  C  CA   . LEU A 1 204 ? 39.641  -13.287 -3.493  1   40.39   ? 210  LEU A CA   1 ? 
ATOM   2987  C  C    . LEU A 1 204 ? 39.335  -14.705 -2.98   1   34.609  ? 210  LEU A C    1 ? 
ATOM   2988  O  O    . LEU A 1 204 ? 38.612  -14.876 -1.978  1   33.376  ? 210  LEU A O    1 ? 
ATOM   2989  C  CB   . LEU A 1 204 ? 38.737  -12.917 -4.666  1   36.384  ? 210  LEU A CB   1 ? 
ATOM   2990  C  CG   . LEU A 1 204 ? 38.74   -11.428 -4.998  1   35.541  ? 210  LEU A CG   1 ? 
ATOM   2991  C  CD1  . LEU A 1 204 ? 38.186  -11.151 -6.385  1   36.757  ? 210  LEU A CD1  1 ? 
ATOM   2992  C  CD2  . LEU A 1 204 ? 37.942  -10.697 -3.936  1   35.736  ? 210  LEU A CD2  1 ? 
ATOM   2993  H  H    . LEU A 1 204 ? 41.259  -12.77  -4.687  1   37.003  ? 210  LEU A H    1 c 
ATOM   2994  H  HA   . LEU A 1 204 ? 39.447  -12.666 -2.747  1   37.607  ? 210  LEU A HA   1 c 
ATOM   2995  H  HB2  . LEU A 1 204 ? 39.037  -13.417 -5.46   1   37.051  ? 210  LEU A HB2  1 c 
ATOM   2996  H  HB3  . LEU A 1 204 ? 37.816  -13.192 -4.451  1   37.031  ? 210  LEU A HB3  1 c 
ATOM   2997  H  HG   . LEU A 1 204 ? 39.676  -11.101 -4.965  1   35.962  ? 210  LEU A HG   1 c 
ATOM   2998  H  HD11 . LEU A 1 204 ? 38.669  -11.682 -7.041  1   36.396  ? 210  LEU A HD11 1 c 
ATOM   2999  H  HD12 . LEU A 1 204 ? 38.291  -10.207 -6.594  1   36.392  ? 210  LEU A HD12 1 c 
ATOM   3000  H  HD13 . LEU A 1 204 ? 37.244  -11.384 -6.412  1   36.385  ? 210  LEU A HD13 1 c 
ATOM   3001  H  HD21 . LEU A 1 204 ? 38.395  -10.768 -3.08   1   35.683  ? 210  LEU A HD21 1 c 
ATOM   3002  H  HD22 . LEU A 1 204 ? 37.056  -11.09  -3.867  1   35.688  ? 210  LEU A HD22 1 c 
ATOM   3003  H  HD23 . LEU A 1 204 ? 37.861  -9.76   -4.181  1   35.681  ? 210  LEU A HD23 1 c 
ATOM   3004  N  N    . GLN A 1 205 ? 39.906  -15.731 -3.617  1   32.036  ? 211  GLN A N    1 ? 
ATOM   3005  C  CA   . GLN A 1 205 ? 39.757  -17.102 -3.118  1   34.886  ? 211  GLN A CA   1 ? 
ATOM   3006  C  C    . GLN A 1 205 ? 40.288  -17.229 -1.687  1   37.471  ? 211  GLN A C    1 ? 
ATOM   3007  O  O    . GLN A 1 205 ? 39.703  -17.902 -0.813  1   36.05   ? 211  GLN A O    1 ? 
ATOM   3008  C  CB   . GLN A 1 205 ? 40.505  -18.077 -4.025  1   37.007  ? 211  GLN A CB   1 ? 
ATOM   3009  C  CG   . GLN A 1 205 ? 40.212  -19.546 -3.727  1   37.22   ? 211  GLN A CG   1 ? 
ATOM   3010  C  CD   . GLN A 1 205 ? 38.873  -20.042 -4.199  1   31.187  ? 211  GLN A CD   1 ? 
ATOM   3011  O  OE1  . GLN A 1 205 ? 38.398  -19.702 -5.278  1   34.988  ? 211  GLN A OE1  1 ? 
ATOM   3012  N  NE2  . GLN A 1 205 ? 38.261  -20.877 -3.391  1   30.432  ? 211  GLN A NE2  1 ? 
ATOM   3013  H  H    . GLN A 1 205 ? 40.393  -15.583 -4.376  1   33.364  ? 211  GLN A H    1 c 
ATOM   3014  H  HA   . GLN A 1 205 ? 38.797  -17.333 -3.125  1   35.074  ? 211  GLN A HA   1 c 
ATOM   3015  H  HB2  . GLN A 1 205 ? 40.267  -17.887 -4.956  1   36.549  ? 211  GLN A HB2  1 c 
ATOM   3016  H  HB3  . GLN A 1 205 ? 41.466  -17.922 -3.927  1   36.499  ? 211  GLN A HB3  1 c 
ATOM   3017  H  HG2  . GLN A 1 205 ? 40.905  -20.098 -4.149  1   35.658  ? 211  GLN A HG2  1 c 
ATOM   3018  H  HG3  . GLN A 1 205 ? 40.272  -19.693 -2.76   1   35.61   ? 211  GLN A HG3  1 c 
ATOM   3019  H  HE21 . GLN A 1 205 ? 37.396  -21.046 -3.507  1   30.713  ? 211  GLN A HE21 1 c 
ATOM   3020  H  HE22 . GLN A 1 205 ? 38.706  -21.275 -2.733  1   30.755  ? 211  GLN A HE22 1 c 
ATOM   3021  N  N    . GLU A 1 206 ? 41.401  -16.544 -1.436  1   33.888  ? 212  GLU A N    1 ? 
ATOM   3022  C  CA   . GLU A 1 206 ? 42.109  -16.739 -0.185  1   39.764  ? 212  GLU A CA   1 ? 
ATOM   3023  C  C    . GLU A 1 206 ? 41.48   -15.928 0.948   1   38.513  ? 212  GLU A C    1 ? 
ATOM   3024  O  O    . GLU A 1 206 ? 41.549  -16.352 2.087   1   34.122  ? 212  GLU A O    1 ? 
ATOM   3025  C  CB   . GLU A 1 206 ? 43.578  -16.39  -0.389  1   48.006  ? 212  GLU A CB   1 ? 
ATOM   3026  C  CG   . GLU A 1 206 ? 44.488  -17.004 0.668   1   56.199  ? 212  GLU A CG   1 ? 
ATOM   3027  C  CD   . GLU A 1 206 ? 45.955  -16.66  0.472   1   59.459  ? 212  GLU A CD   1 ? 
ATOM   3028  O  OE1  . GLU A 1 206 ? 46.475  -15.865 1.3     1   60.898  ? 212  GLU A OE1  1 ? 
ATOM   3029  O  OE2  . GLU A 1 206 ? 46.554  -17.161 -0.5    1   54.035  ? 212  GLU A OE2  1 ? 
ATOM   3030  H  H    . GLU A 1 206 ? 41.734  -15.958 -2.053  1   36.086  ? 212  GLU A H    1 c 
ATOM   3031  H  HA   . GLU A 1 206 ? 42.056  -17.7   0.054   1   39.643  ? 212  GLU A HA   1 c 
ATOM   3032  H  HB2  . GLU A 1 206 ? 43.859  -16.705 -1.274  1   47.469  ? 212  GLU A HB2  1 c 
ATOM   3033  H  HB3  . GLU A 1 206 ? 43.678  -15.415 -0.373  1   47.573  ? 212  GLU A HB3  1 c 
ATOM   3034  H  HG2  . GLU A 1 206 ? 44.208  -16.689 1.554   1   54.858  ? 212  GLU A HG2  1 c 
ATOM   3035  H  HG3  . GLU A 1 206 ? 44.387  -17.976 0.653   1   54.827  ? 212  GLU A HG3  1 c 
ATOM   3036  N  N    . ARG A 1 207 ? 40.808  -14.816 0.622   1   39.288  ? 213  ARG A N    1 ? 
ATOM   3037  C  CA   . ARG A 1 207 ? 40.408  -13.855 1.625   1   39.137  ? 213  ARG A CA   1 ? 
ATOM   3038  C  C    . ARG A 1 207 ? 38.917  -13.834 1.863   1   34.098  ? 213  ARG A C    1 ? 
ATOM   3039  O  O    . ARG A 1 207 ? 38.516  -13.339 2.908   1   35.357  ? 213  ARG A O    1 ? 
ATOM   3040  C  CB   . ARG A 1 207 ? 40.852  -12.443 1.244   1   36.398  ? 213  ARG A CB   1 ? 
ATOM   3041  C  CG   . ARG A 1 207 ? 42.345  -12.306 1.472   1   32.25   ? 213  ARG A CG   1 ? 
ATOM   3042  C  CD   . ARG A 1 207 ? 42.851  -10.909 1.141   1   30.991  ? 213  ARG A CD   1 ? 
ATOM   3043  N  NE   . ARG A 1 207 ? 44.32   -10.896 1.023   1   32.298  ? 213  ARG A NE   1 ? 
ATOM   3044  C  CZ   . ARG A 1 207 ? 45.109  -9.822  0.959   1   32.03   ? 213  ARG A CZ   1 ? 
ATOM   3045  N  NH1  . ARG A 1 207 ? 44.608  -8.597  1.014   1   31.526  ? 213  ARG A NH1  1 ? 
ATOM   3046  N  NH2  . ARG A 1 207 ? 46.418  -9.994  0.955   1   33.762  ? 213  ARG A NH2  1 ? 
ATOM   3047  H  H    . ARG A 1 207 ? 40.611  -14.647 -0.254  1   38.994  ? 213  ARG A H    1 c 
ATOM   3048  H  HA   . ARG A 1 207 ? 40.851  -14.093 2.478   1   37.59   ? 213  ARG A HA   1 c 
ATOM   3049  H  HB2  . ARG A 1 207 ? 40.647  -12.273 0.299   1   35.985  ? 213  ARG A HB2  1 c 
ATOM   3050  H  HB3  . ARG A 1 207 ? 40.375  -11.782 1.79    1   35.972  ? 213  ARG A HB3  1 c 
ATOM   3051  H  HG2  . ARG A 1 207 ? 42.548  -12.505 2.409   1   33.021  ? 213  ARG A HG2  1 c 
ATOM   3052  H  HG3  . ARG A 1 207 ? 42.818  -12.959 0.912   1   32.881  ? 213  ARG A HG3  1 c 
ATOM   3053  H  HD2  . ARG A 1 207 ? 42.455  -10.608 0.298   1   31.575  ? 213  ARG A HD2  1 c 
ATOM   3054  H  HD3  . ARG A 1 207 ? 42.577  -10.287 1.846   1   31.576  ? 213  ARG A HD3  1 c 
ATOM   3055  H  HE   . ARG A 1 207 ? 44.72   -11.669 0.99    1   31.961  ? 213  ARG A HE   1 c 
ATOM   3056  H  HH11 . ARG A 1 207 ? 43.978  -8.402  1.605   1   31.686  ? 213  ARG A HH11 1 c 
ATOM   3057  H  HH12 . ARG A 1 207 ? 44.909  -7.976  0.46    1   31.682  ? 213  ARG A HH12 1 c 
ATOM   3058  H  HH21 . ARG A 1 207 ? 46.767  -10.756 1.242   1   33.198  ? 213  ARG A HH21 1 c 
ATOM   3059  H  HH22 . ARG A 1 207 ? 46.943  -9.342  0.667   1   33.202  ? 213  ARG A HH22 1 c 
ATOM   3060  N  N    . ILE A 1 208 ? 38.125  -14.375 0.935   1   36.893  ? 214  ILE A N    1 ? 
ATOM   3061  C  CA   . ILE A 1 208 ? 36.688  -14.427 1.086   1   33.138  ? 214  ILE A CA   1 ? 
ATOM   3062  C  C    . ILE A 1 208 ? 36.174  -15.841 0.953   1   28.962  ? 214  ILE A C    1 ? 
ATOM   3063  O  O    . ILE A 1 208 ? 35.468  -16.334 1.826   1   33.574  ? 214  ILE A O    1 ? 
ATOM   3064  C  CB   . ILE A 1 208 ? 35.969  -13.517 0.08    1   33.402  ? 214  ILE A CB   1 ? 
ATOM   3065  C  CG1  . ILE A 1 208 ? 36.513  -12.094 0.138   1   34.252  ? 214  ILE A CG1  1 ? 
ATOM   3066  C  CG2  . ILE A 1 208 ? 34.468  -13.58  0.369   1   32.584  ? 214  ILE A CG2  1 ? 
ATOM   3067  C  CD1  . ILE A 1 208 ? 36.302  -11.429 1.479   1   39.479  ? 214  ILE A CD1  1 ? 
ATOM   3068  H  H    . ILE A 1 208 ? 38.496  -14.714 0.172   1   35.34   ? 214  ILE A H    1 c 
ATOM   3069  H  HA   . ILE A 1 208 ? 36.467  -14.116 1.983   1   33.116  ? 214  ILE A HA   1 c 
ATOM   3070  H  HB   . ILE A 1 208 ? 36.126  -13.869 -0.819  1   33.341  ? 214  ILE A HB   1 c 
ATOM   3071  H  HG12 . ILE A 1 208 ? 37.471  -12.111 -0.061  1   35.199  ? 214  ILE A HG12 1 c 
ATOM   3072  H  HG13 . ILE A 1 208 ? 36.072  -11.559 -0.553  1   35.192  ? 214  ILE A HG13 1 c 
ATOM   3073  H  HG21 . ILE A 1 208 ? 34.02   -12.84  -0.076  1   32.822  ? 214  ILE A HG21 1 c 
ATOM   3074  H  HG22 . ILE A 1 208 ? 34.316  -13.516 1.327   1   32.848  ? 214  ILE A HG22 1 c 
ATOM   3075  H  HG23 . ILE A 1 208 ? 34.104  -14.419 0.039   1   32.806  ? 214  ILE A HG23 1 c 
ATOM   3076  H  HD11 . ILE A 1 208 ? 35.347  -11.314 1.639   1   37.798  ? 214  ILE A HD11 1 c 
ATOM   3077  H  HD12 . ILE A 1 208 ? 36.733  -10.553 1.468   1   37.817  ? 214  ILE A HD12 1 c 
ATOM   3078  H  HD13 . ILE A 1 208 ? 36.686  -11.966 2.195   1   37.751  ? 214  ILE A HD13 1 c 
ATOM   3079  N  N    . LEU A 1 209 ? 36.495  -16.474 -0.167  1   30.395  ? 215  LEU A N    1 ? 
ATOM   3080  C  CA   . LEU A 1 209 ? 35.839  -17.721 -0.517  1   31.306  ? 215  LEU A CA   1 ? 
ATOM   3081  C  C    . LEU A 1 209 ? 36.224  -18.845 0.458   1   34.936  ? 215  LEU A C    1 ? 
ATOM   3082  O  O    . LEU A 1 209 ? 35.34   -19.543 0.938   1   39.381  ? 215  LEU A O    1 ? 
ATOM   3083  C  CB   . LEU A 1 209 ? 36.252  -17.984 -1.962  1   32.428  ? 215  LEU A CB   1 ? 
ATOM   3084  C  CG   . LEU A 1 209 ? 35.304  -17.568 -3.079  1   33.942  ? 215  LEU A CG   1 ? 
ATOM   3085  C  CD1  . LEU A 1 209 ? 34.54   -16.27  -2.974  1   31.149  ? 215  LEU A CD1  1 ? 
ATOM   3086  C  CD2  . LEU A 1 209 ? 36.09   -17.62  -4.351  1   34.449  ? 215  LEU A CD2  1 ? 
ATOM   3087  H  H    . LEU A 1 209 ? 37.125  -16.123 -0.728  1   30.384  ? 215  LEU A H    1 c 
ATOM   3088  H  HA   . LEU A 1 209 ? 34.859  -17.583 -0.475  1   31.982  ? 215  LEU A HA   1 c 
ATOM   3089  H  HB2  . LEU A 1 209 ? 37.118  -17.546 -2.116  1   32.529  ? 215  LEU A HB2  1 c 
ATOM   3090  H  HB3  . LEU A 1 209 ? 36.42   -18.951 -2.055  1   32.524  ? 215  LEU A HB3  1 c 
ATOM   3091  H  HG   . LEU A 1 209 ? 34.617  -18.28  -3.149  1   33.207  ? 215  LEU A HG   1 c 
ATOM   3092  H  HD11 . LEU A 1 209 ? 33.932  -16.311 -2.217  1   31.958  ? 215  LEU A HD11 1 c 
ATOM   3093  H  HD12 . LEU A 1 209 ? 34.03   -16.125 -3.789  1   31.97   ? 215  LEU A HD12 1 c 
ATOM   3094  H  HD13 . LEU A 1 209 ? 35.163  -15.535 -2.848  1   31.958  ? 215  LEU A HD13 1 c 
ATOM   3095  H  HD21 . LEU A 1 209 ? 36.437  -18.517 -4.479  1   34.264  ? 215  LEU A HD21 1 c 
ATOM   3096  H  HD22 . LEU A 1 209 ? 36.828  -16.99  -4.306  1   34.275  ? 215  LEU A HD22 1 c 
ATOM   3097  H  HD23 . LEU A 1 209 ? 35.513  -17.388 -5.098  1   34.254  ? 215  LEU A HD23 1 c 
ATOM   3098  N  N    . ASP A 1 210 ? 37.531  -19.053 0.721   1   35.149  ? 216  ASP A N    1 ? 
ATOM   3099  C  CA   . ASP A 1 210 ? 37.991  -20.171 1.537   1   37.896  ? 216  ASP A CA   1 ? 
ATOM   3100  C  C    . ASP A 1 210 ? 37.644  -19.961 3.01    1   38.781  ? 216  ASP A C    1 ? 
ATOM   3101  O  O    . ASP A 1 210 ? 37.076  -20.82  3.68    1   41.031  ? 216  ASP A O    1 ? 
ATOM   3102  C  CB   . ASP A 1 210 ? 39.471  -20.432 1.339   1   37.271  ? 216  ASP A CB   1 ? 
ATOM   3103  C  CG   . ASP A 1 210 ? 39.847  -21.136 0.036   1   45.035  ? 216  ASP A CG   1 ? 
ATOM   3104  O  OD1  . ASP A 1 210 ? 38.949  -21.774 -0.591  1   37.498  ? 216  ASP A OD1  1 ? 
ATOM   3105  O  OD2  . ASP A 1 210 ? 41.051  -21.082 -0.324  1   48.092  ? 216  ASP A OD2  1 ? 
ATOM   3106  H  H    . ASP A 1 210 ? 38.151  -18.483 0.366   1   35.676  ? 216  ASP A H    1 c 
ATOM   3107  H  HA   . ASP A 1 210 ? 37.519  -20.979 1.233   1   37.423  ? 216  ASP A HA   1 c 
ATOM   3108  H  HB2  . ASP A 1 210 ? 39.957  -19.583 1.364   1   39.039  ? 216  ASP A HB2  1 c 
ATOM   3109  H  HB3  . ASP A 1 210 ? 39.795  -20.983 2.081   1   39.066  ? 216  ASP A HB3  1 c 
ATOM   3110  N  N    . PRO A 1 211 ? 37.949  -18.801 3.596   1   37.437  ? 217  PRO A N    1 ? 
ATOM   3111  C  CA   . PRO A 1 211 ? 37.618  -18.595 5       1   39.929  ? 217  PRO A CA   1 ? 
ATOM   3112  C  C    . PRO A 1 211 ? 36.133  -18.745 5.337   1   36.891  ? 217  PRO A C    1 ? 
ATOM   3113  O  O    . PRO A 1 211 ? 35.781  -19.08  6.465   1   36.69   ? 217  PRO A O    1 ? 
ATOM   3114  C  CB   . PRO A 1 211 ? 38.115  -17.174 5.295   1   40.867  ? 217  PRO A CB   1 ? 
ATOM   3115  C  CG   . PRO A 1 211 ? 38.996  -16.81  4.119   1   40.465  ? 217  PRO A CG   1 ? 
ATOM   3116  C  CD   . PRO A 1 211 ? 38.573  -17.642 2.945   1   37.331  ? 217  PRO A CD   1 ? 
ATOM   3117  H  HA   . PRO A 1 211 ? 38.142  -19.239 5.54    1   39.04   ? 217  PRO A HA   1 c 
ATOM   3118  H  HB2  . PRO A 1 211 ? 37.358  -16.546 5.372   1   40.538  ? 217  PRO A HB2  1 c 
ATOM   3119  H  HB3  . PRO A 1 211 ? 38.628  -17.151 6.137   1   40.535  ? 217  PRO A HB3  1 c 
ATOM   3120  H  HG2  . PRO A 1 211 ? 38.902  -15.858 3.909   1   39.785  ? 217  PRO A HG2  1 c 
ATOM   3121  H  HG3  . PRO A 1 211 ? 39.936  -16.985 4.334   1   39.808  ? 217  PRO A HG3  1 c 
ATOM   3122  H  HD2  . PRO A 1 211 ? 37.931  -17.159 2.384   1   37.94   ? 217  PRO A HD2  1 c 
ATOM   3123  H  HD3  . PRO A 1 211 ? 39.347  -17.906 2.404   1   37.994  ? 217  PRO A HD3  1 c 
ATOM   3124  N  N    . TYR A 1 212 ? 35.264  -18.4   4.389   1   41.44   ? 218  TYR A N    1 ? 
ATOM   3125  C  CA   . TYR A 1 212 ? 33.83   -18.505 4.581   1   38.352  ? 218  TYR A CA   1 ? 
ATOM   3126  C  C    . TYR A 1 212 ? 33.46   -19.967 4.851   1   42.475  ? 218  TYR A C    1 ? 
ATOM   3127  O  O    . TYR A 1 212 ? 32.784  -20.247 5.837   1   36.537  ? 218  TYR A O    1 ? 
ATOM   3128  C  CB   . TYR A 1 212 ? 33.058  -17.95  3.38    1   40.271  ? 218  TYR A CB   1 ? 
ATOM   3129  C  CG   . TYR A 1 212 ? 31.56   -17.93  3.657   1   36.292  ? 218  TYR A CG   1 ? 
ATOM   3130  C  CD1  . TYR A 1 212 ? 31.039  -17.076 4.62    1   36.415  ? 218  TYR A CD1  1 ? 
ATOM   3131  C  CD2  . TYR A 1 212 ? 30.681  -18.769 2.981   1   34.912  ? 218  TYR A CD2  1 ? 
ATOM   3132  C  CE1  . TYR A 1 212 ? 29.686  -17.057 4.915   1   34.118  ? 218  TYR A CE1  1 ? 
ATOM   3133  C  CE2  . TYR A 1 212 ? 29.327  -18.761 3.266   1   38.716  ? 218  TYR A CE2  1 ? 
ATOM   3134  C  CZ   . TYR A 1 212 ? 28.832  -17.902 4.239   1   39.923  ? 218  TYR A CZ   1 ? 
ATOM   3135  O  OH   . TYR A 1 212 ? 27.513  -17.853 4.572   1   43.368  ? 218  TYR A OH   1 ? 
ATOM   3136  H  H    . TYR A 1 212 ? 35.576  -18.076 3.593   1   39.595  ? 218  TYR A H    1 c 
ATOM   3137  H  HA   . TYR A 1 212 ? 33.587  -17.969 5.381   1   39.968  ? 218  TYR A HA   1 c 
ATOM   3138  H  HB2  . TYR A 1 212 ? 33.367  -17.036 3.195   1   38.859  ? 218  TYR A HB2  1 c 
ATOM   3139  H  HB3  . TYR A 1 212 ? 33.238  -18.513 2.595   1   38.852  ? 218  TYR A HB3  1 c 
ATOM   3140  H  HD1  . TYR A 1 212 ? 31.622  -16.505 5.095   1   35.907  ? 218  TYR A HD1  1 c 
ATOM   3141  H  HD2  . TYR A 1 212 ? 31.014  -19.364 2.328   1   36.167  ? 218  TYR A HD2  1 c 
ATOM   3142  H  HE1  . TYR A 1 212 ? 29.351  -16.477 5.576   1   36.15   ? 218  TYR A HE1  1 c 
ATOM   3143  H  HE2  . TYR A 1 212 ? 28.743  -19.338 2.805   1   38.047  ? 218  TYR A HE2  1 c 
ATOM   3144  H  HH   . TYR A 1 212 ? 27.111  -17.299 4.045   0   43.04   ? 218  TYR A HH   1 c 
ATOM   3145  N  N    . MET A 1 213 ? 33.999  -20.876 4.022   1   39.306  ? 219  MET A N    1 ? 
ATOM   3146  C  CA   . MET A 1 213 ? 33.643  -22.278 4.061   1   42.124  ? 219  MET A CA   1 ? 
ATOM   3147  C  C    . MET A 1 213 ? 34.367  -23.027 5.173   1   47.002  ? 219  MET A C    1 ? 
ATOM   3148  O  O    . MET A 1 213 ? 33.791  -23.955 5.744   1   48.237  ? 219  MET A O    1 ? 
ATOM   3149  C  CB   . MET A 1 213 ? 33.936  -22.955 2.716   1   45.218  ? 219  MET A CB   1 ? 
ATOM   3150  C  CG   . MET A 1 213 ? 32.99   -22.497 1.618   1   47.843  ? 219  MET A CG   1 ? 
ATOM   3151  S  SD   . MET A 1 213 ? 31.254  -22.602 2.097   1   49.262  ? 219  MET A SD   1 ? 
ATOM   3152  C  CE   . MET A 1 213 ? 30.889  -24.354 2.248   1   47.202  ? 219  MET A CE   1 ? 
ATOM   3153  H  H    . MET A 1 213 ? 34.614  -20.601 3.405   1   40.721  ? 219  MET A H    1 c 
ATOM   3154  H  HA   . MET A 1 213 ? 32.673  -22.336 4.247   1   42.952  ? 219  MET A HA   1 c 
ATOM   3155  H  HB2  . MET A 1 213 ? 34.86   -22.755 2.453   1   45.047  ? 219  MET A HB2  1 c 
ATOM   3156  H  HB3  . MET A 1 213 ? 33.855  -23.926 2.826   1   45.081  ? 219  MET A HB3  1 c 
ATOM   3157  H  HG2  . MET A 1 213 ? 33.194  -21.571 1.388   1   47.388  ? 219  MET A HG2  1 c 
ATOM   3158  H  HG3  . MET A 1 213 ? 33.131  -23.044 0.819   1   47.449  ? 219  MET A HG3  1 c 
ATOM   3159  H  HE1  . MET A 1 213 ? 29.957  -24.47  2.509   1   47.708  ? 219  MET A HE1  1 c 
ATOM   3160  H  HE2  . MET A 1 213 ? 31.044  -24.793 1.391   1   47.708  ? 219  MET A HE2  1 c 
ATOM   3161  H  HE3  . MET A 1 213 ? 31.469  -24.748 2.925   1   47.708  ? 219  MET A HE3  1 c 
ATOM   3162  N  N    . ASN A 1 214 ? 35.614  -22.629 5.462   1   45.025  ? 220  ASN A N    1 ? 
ATOM   3163  C  CA   . ASN A 1 214 ? 36.527  -23.44  6.257   1   47.531  ? 220  ASN A CA   1 ? 
ATOM   3164  C  C    . ASN A 1 214 ? 36.488  -23.048 7.725   1   45.009  ? 220  ASN A C    1 ? 
ATOM   3165  O  O    . ASN A 1 214 ? 37.124  -23.704 8.542   1   44.175  ? 220  ASN A O    1 ? 
ATOM   3166  C  CB   . ASN A 1 214 ? 37.989  -23.257 5.863   1   45.242  ? 220  ASN A CB   1 ? 
ATOM   3167  C  CG   . ASN A 1 214 ? 38.276  -23.826 4.507   1   48.889  ? 220  ASN A CG   1 ? 
ATOM   3168  O  OD1  . ASN A 1 214 ? 37.453  -24.579 3.955   1   47.416  ? 220  ASN A OD1  1 ? 
ATOM   3169  N  ND2  . ASN A 1 214 ? 39.421  -23.434 3.97    1   51.657  ? 220  ASN A ND2  1 ? 
ATOM   3170  H  H    . ASN A 1 214 ? 35.91   -21.824 5.147   1   45.929  ? 220  ASN A H    1 c 
ATOM   3171  H  HA   . ASN A 1 214 ? 36.293  -24.391 6.16    1   46.186  ? 220  ASN A HA   1 c 
ATOM   3172  H  HB2  . ASN A 1 214 ? 38.206  -22.303 5.864   1   46.592  ? 220  ASN A HB2  1 c 
ATOM   3173  H  HB3  . ASN A 1 214 ? 38.562  -23.698 6.521   1   46.558  ? 220  ASN A HB3  1 c 
ATOM   3174  H  HD21 . ASN A 1 214 ? 39.64   -23.704 3.155   1   50.771  ? 220  ASN A HD21 1 c 
ATOM   3175  H  HD22 . ASN A 1 214 ? 39.969  -22.902 4.423   1   50.71   ? 220  ASN A HD22 1 c 
ATOM   3176  N  N    . ASN A 1 215 ? 35.784  -21.971 8.048   1   37.818  ? 221  ASN A N    1 ? 
ATOM   3177  C  CA   . ASN A 1 215 ? 35.741  -21.531 9.428   1   46.202  ? 221  ASN A CA   1 ? 
ATOM   3178  C  C    . ASN A 1 215 ? 34.275  -21.35  9.806   1   49.583  ? 221  ASN A C    1 ? 
ATOM   3179  O  O    . ASN A 1 215 ? 33.634  -20.373 9.388   1   57.863  ? 221  ASN A O    1 ? 
ATOM   3180  C  CB   . ASN A 1 215 ? 36.64   -20.308 9.618   1   44.521  ? 221  ASN A CB   1 ? 
ATOM   3181  C  CG   . ASN A 1 215 ? 36.575  -19.739 11.017  1   52.387  ? 221  ASN A CG   1 ? 
ATOM   3182  O  OD1  . ASN A 1 215 ? 35.984  -20.317 11.95   1   48.026  ? 221  ASN A OD1  1 ? 
ATOM   3183  N  ND2  . ASN A 1 215 ? 37.198  -18.587 11.179  1   47.129  ? 221  ASN A ND2  1 ? 
ATOM   3184  H  H    . ASN A 1 215 ? 35.328  -21.499 7.412   1   41.416  ? 221  ASN A H    1 c 
ATOM   3185  H  HA   . ASN A 1 215 ? 36.112  -22.247 9.99    1   44.811  ? 221  ASN A HA   1 c 
ATOM   3186  H  HB2  . ASN A 1 215 ? 37.564  -20.557 9.419   1   46.598  ? 221  ASN A HB2  1 c 
ATOM   3187  H  HB3  . ASN A 1 215 ? 36.372  -19.615 8.982   1   46.551  ? 221  ASN A HB3  1 c 
ATOM   3188  H  HD21 . ASN A 1 215 ? 37.197  -18.192 11.973  1   48.677  ? 221  ASN A HD21 1 c 
ATOM   3189  H  HD22 . ASN A 1 215 ? 37.618  -18.208 10.496  1   48.656  ? 221  ASN A HD22 1 c 
ATOM   3190  N  N    . ASP A 1 216 ? 33.776  -22.29  10.614  1   52.346  ? 222  ASP A N    1 ? 
ATOM   3191  C  CA   . ASP A 1 216 ? 32.408  -22.287 11.123  1   60.524  ? 222  ASP A CA   1 ? 
ATOM   3192  C  C    . ASP A 1 216 ? 32.16   -21.351 12.306  1   57.137  ? 222  ASP A C    1 ? 
ATOM   3193  O  O    . ASP A 1 216 ? 31.012  -21.231 12.752  1   53.512  ? 222  ASP A O    1 ? 
ATOM   3194  C  CB   . ASP A 1 216 ? 32.045  -23.655 11.675  1   58.156  ? 222  ASP A CB   1 ? 
ATOM   3195  C  CG   . ASP A 1 216 ? 31.858  -24.711 10.614  1   53.975  ? 222  ASP A CG   1 ? 
ATOM   3196  O  OD1  . ASP A 1 216 ? 31.916  -24.343 9.429   1   49.48   ? 222  ASP A OD1  1 ? 
ATOM   3197  O  OD2  . ASP A 1 216 ? 31.668  -25.877 10.996  1   65.979  ? 222  ASP A OD2  1 ? 
ATOM   3198  H  H    . ASP A 1 216 ? 34.323  -22.978 10.865  1   53.322  ? 222  ASP A H    1 c 
ATOM   3199  H  HA   . ASP A 1 216 ? 31.796  -22.049 10.39   1   57.755  ? 222  ASP A HA   1 c 
ATOM   3200  H  HB2  . ASP A 1 216 ? 32.747  -23.952 12.29   1   57.636  ? 222  ASP A HB2  1 c 
ATOM   3201  H  HB3  . ASP A 1 216 ? 31.208  -23.597 12.18   1   57.632  ? 222  ASP A HB3  1 c 
ATOM   3202  N  N    . ARG A 1 217 ? 33.222  -20.731 12.834  1   56.941  ? 223  ARG A N    1 ? 
ATOM   3203  C  CA   . ARG A 1 217 ? 33.173  -20.144 14.156  1   57.695  ? 223  ARG A CA   1 ? 
ATOM   3204  C  C    . ARG A 1 217 ? 33.109  -18.616 14.108  1   59.983  ? 223  ARG A C    1 ? 
ATOM   3205  O  O    . ARG A 1 217 ? 33.066  -17.975 15.162  1   65.532  ? 223  ARG A O    1 ? 
ATOM   3206  C  CB   . ARG A 1 217 ? 34.401  -20.59  14.955  1   68.728  ? 223  ARG A CB   1 ? 
ATOM   3207  C  CG   . ARG A 1 217 ? 34.587  -22.077 15.24   1   77.497  ? 223  ARG A CG   1 ? 
ATOM   3208  C  CD   . ARG A 1 217 ? 35.836  -22.244 16.132  1   93.137  ? 223  ARG A CD   1 ? 
ATOM   3209  N  NE   . ARG A 1 217 ? 36.158  -23.607 16.583  1   115.569 ? 223  ARG A NE   1 ? 
ATOM   3210  C  CZ   . ARG A 1 217 ? 37.261  -23.988 17.253  1   122.347 ? 223  ARG A CZ   1 ? 
ATOM   3211  N  NH1  . ARG A 1 217 ? 38.171  -23.105 17.642  1   122.593 ? 223  ARG A NH1  1 ? 
ATOM   3212  N  NH2  . ARG A 1 217 ? 37.452  -25.267 17.536  1   116.672 ? 223  ARG A NH2  1 ? 
ATOM   3213  H  H    . ARG A 1 217 ? 33.997  -20.67  12.356  1   57.081  ? 223  ARG A H    1 c 
ATOM   3214  H  HA   . ARG A 1 217 ? 32.365  -20.477 14.62   1   59.882  ? 223  ARG A HA   1 c 
ATOM   3215  H  HB2  . ARG A 1 217 ? 35.196  -20.273 14.476  1   67.759  ? 223  ARG A HB2  1 c 
ATOM   3216  H  HB3  . ARG A 1 217 ? 34.381  -20.119 15.816  1   67.936  ? 223  ARG A HB3  1 c 
ATOM   3217  H  HG2  . ARG A 1 217 ? 33.799  -22.43  15.708  1   78.594  ? 223  ARG A HG2  1 c 
ATOM   3218  H  HG3  . ARG A 1 217 ? 34.713  -22.567 14.399  1   78.593  ? 223  ARG A HG3  1 c 
ATOM   3219  H  HD2  . ARG A 1 217 ? 36.603  -21.892 15.635  1   94.027  ? 223  ARG A HD2  1 c 
ATOM   3220  H  HD3  . ARG A 1 217 ? 35.72   -21.675 16.92   1   93.867  ? 223  ARG A HD3  1 c 
ATOM   3221  H  HE   . ARG A 1 217 ? 35.579  -24.23  16.397  1   111.495 ? 223  ARG A HE   1 c 
ATOM   3222  H  HH11 . ARG A 1 217 ? 37.929  -22.26  17.822  1   122.277 ? 223  ARG A HH11 1 c 
ATOM   3223  H  HH12 . ARG A 1 217 ? 39.024  -23.365 17.72   1   122.386 ? 223  ARG A HH12 1 c 
ATOM   3224  H  HH21 . ARG A 1 217 ? 36.794  -25.847 17.425  1   118.321 ? 223  ARG A HH21 1 c 
ATOM   3225  H  HH22 . ARG A 1 217 ? 38.239  -25.54  17.834  1   118.436 ? 223  ARG A HH22 1 c 
ATOM   3226  N  N    . GLU A 1 218 ? 33.089  -18.004 12.918  1   55.342  ? 224  GLU A N    1 ? 
ATOM   3227  C  CA   . GLU A 1 218 ? 32.905  -16.557 12.882  1   52.492  ? 224  GLU A CA   1 ? 
ATOM   3228  C  C    . GLU A 1 218 ? 31.618  -16.221 13.633  1   50.016  ? 224  GLU A C    1 ? 
ATOM   3229  O  O    . GLU A 1 218 ? 30.586  -16.84  13.391  1   48.412  ? 224  GLU A O    1 ? 
ATOM   3230  C  CB   . GLU A 1 218 ? 32.825  -15.953 11.483  1   48.395  ? 224  GLU A CB   1 ? 
ATOM   3231  C  CG   . GLU A 1 218 ? 34.151  -15.873 10.739  1   50.599  ? 224  GLU A CG   1 ? 
ATOM   3232  C  CD   . GLU A 1 218 ? 34.961  -14.641 11.119  1   56.244  ? 224  GLU A CD   1 ? 
ATOM   3233  O  OE1  . GLU A 1 218 ? 35.724  -14.212 10.25   1   50.482  ? 224  GLU A OE1  1 ? 
ATOM   3234  O  OE2  . GLU A 1 218 ? 34.834  -14.108 12.237  1   49.965  ? 224  GLU A OE2  1 ? 
ATOM   3235  H  H    . GLU A 1 218 ? 33.19   -18.47  12.139  1   55.776  ? 224  GLU A H    1 c 
ATOM   3236  H  HA   . GLU A 1 218 ? 33.666  -16.14  13.36   1   51.788  ? 224  GLU A HA   1 c 
ATOM   3237  H  HB2  . GLU A 1 218 ? 32.203  -16.489 10.95   1   49.939  ? 224  GLU A HB2  1 c 
ATOM   3238  H  HB3  . GLU A 1 218 ? 32.452  -15.049 11.553  1   49.863  ? 224  GLU A HB3  1 c 
ATOM   3239  H  HG2  . GLU A 1 218 ? 34.683  -16.674 10.936  1   51.341  ? 224  GLU A HG2  1 c 
ATOM   3240  H  HG3  . GLU A 1 218 ? 33.979  -15.852 9.774   1   51.444  ? 224  GLU A HG3  1 c 
ATOM   3241  N  N    . TRP A 1 219 ? 31.674  -15.238 14.539  1   42.7    ? 225  TRP A N    1 ? 
ATOM   3242  C  CA   . TRP A 1 219 ? 30.55   -15.022 15.435  1   50.981  ? 225  TRP A CA   1 ? 
ATOM   3243  C  C    . TRP A 1 219 ? 29.312  -14.581 14.637  1   51.098  ? 225  TRP A C    1 ? 
ATOM   3244  O  O    . TRP A 1 219 ? 28.188  -15.014 14.904  1   46.481  ? 225  TRP A O    1 ? 
ATOM   3245  C  CB   . TRP A 1 219 ? 30.941  -14.028 16.546  1   55.616  ? 225  TRP A CB   1 ? 
ATOM   3246  C  CG   . TRP A 1 219 ? 31.028  -12.599 16.08   1   60.392  ? 225  TRP A CG   1 ? 
ATOM   3247  C  CD1  . TRP A 1 219 ? 32.123  -11.957 15.567  1   51.053  ? 225  TRP A CD1  1 ? 
ATOM   3248  C  CD2  . TRP A 1 219 ? 29.925  -11.66  16.017  1   59.391  ? 225  TRP A CD2  1 ? 
ATOM   3249  N  NE1  . TRP A 1 219 ? 31.78   -10.673 15.226  1   62.843  ? 225  TRP A NE1  1 ? 
ATOM   3250  C  CE2  . TRP A 1 219 ? 30.443  -10.462 15.474  1   57.065  ? 225  TRP A CE2  1 ? 
ATOM   3251  C  CE3  . TRP A 1 219 ? 28.566  -11.715 16.353  1   56.707  ? 225  TRP A CE3  1 ? 
ATOM   3252  C  CZ2  . TRP A 1 219 ? 29.642  -9.337  15.267  1   59.289  ? 225  TRP A CZ2  1 ? 
ATOM   3253  C  CZ3  . TRP A 1 219 ? 27.775  -10.605 16.126  1   56.675  ? 225  TRP A CZ3  1 ? 
ATOM   3254  C  CH2  . TRP A 1 219 ? 28.305  -9.435  15.584  1   52.718  ? 225  TRP A CH2  1 ? 
ATOM   3255  H  H    . TRP A 1 219 ? 32.41   -14.7   14.598  1   46.343  ? 225  TRP A H    1 c 
ATOM   3256  H  HA   . TRP A 1 219 ? 30.339  -15.891 15.87   1   50.04   ? 225  TRP A HA   1 c 
ATOM   3257  H  HB2  . TRP A 1 219 ? 30.278  -14.088 17.266  1   55.585  ? 225  TRP A HB2  1 c 
ATOM   3258  H  HB3  . TRP A 1 219 ? 31.811  -14.296 16.912  1   55.585  ? 225  TRP A HB3  1 c 
ATOM   3259  H  HD1  . TRP A 1 219 ? 32.989  -12.322 15.486  1   55.786  ? 225  TRP A HD1  1 c 
ATOM   3260  H  HE1  . TRP A 1 219 ? 32.326  -10.085 14.885  1   58.737  ? 225  TRP A HE1  1 c 
ATOM   3261  H  HE3  . TRP A 1 219 ? 28.195  -12.504 16.704  1   57.278  ? 225  TRP A HE3  1 c 
ATOM   3262  H  HZ2  . TRP A 1 219 ? 30      -8.549  14.898  1   57.034  ? 225  TRP A HZ2  1 c 
ATOM   3263  H  HZ3  . TRP A 1 219 ? 26.86   -10.635 16.354  1   55.805  ? 225  TRP A HZ3  1 c 
ATOM   3264  H  HH2  . TRP A 1 219 ? 27.747  -8.687  15.463  1   55.154  ? 225  TRP A HH2  1 c 
ATOM   3265  N  N    . TRP A 1 220 ? 29.523  -13.782 13.579  1   49.086  ? 226  TRP A N    1 ? 
ATOM   3266  C  CA   . TRP A 1 220 ? 28.406  -13.206 12.844  1   43.724  ? 226  TRP A CA   1 ? 
ATOM   3267  C  C    . TRP A 1 220 ? 27.642  -14.258 12.043  1   41.38   ? 226  TRP A C    1 ? 
ATOM   3268  O  O    . TRP A 1 220 ? 26.527  -13.965 11.63   1   39.759  ? 226  TRP A O    1 ? 
ATOM   3269  C  CB   . TRP A 1 220 ? 28.887  -12.088 11.914  1   40.76   ? 226  TRP A CB   1 ? 
ATOM   3270  C  CG   . TRP A 1 220 ? 29.985  -12.453 10.954  1   39.133  ? 226  TRP A CG   1 ? 
ATOM   3271  C  CD1  . TRP A 1 220 ? 31.288  -12.058 11.047  1   46.475  ? 226  TRP A CD1  1 ? 
ATOM   3272  C  CD2  . TRP A 1 220 ? 29.883  -13.177 9.716   1   42.153  ? 226  TRP A CD2  1 ? 
ATOM   3273  N  NE1  . TRP A 1 220 ? 32.01   -12.506 9.982   1   40.7    ? 226  TRP A NE1  1 ? 
ATOM   3274  C  CE2  . TRP A 1 220 ? 31.17   -13.176 9.138   1   43.638  ? 226  TRP A CE2  1 ? 
ATOM   3275  C  CE3  . TRP A 1 220 ? 28.834  -13.796 9.021   1   46.042  ? 226  TRP A CE3  1 ? 
ATOM   3276  C  CZ2  . TRP A 1 220 ? 31.435  -13.797 7.918   1   46.539  ? 226  TRP A CZ2  1 ? 
ATOM   3277  C  CZ3  . TRP A 1 220 ? 29.093  -14.399 7.81    1   44.457  ? 226  TRP A CZ3  1 ? 
ATOM   3278  C  CH2  . TRP A 1 220 ? 30.378  -14.392 7.267   1   50.64   ? 226  TRP A CH2  1 ? 
ATOM   3279  H  H    . TRP A 1 220 ? 30.376  -13.586 13.319  1   48.145  ? 226  TRP A H    1 c 
ATOM   3280  H  HA   . TRP A 1 220 ? 27.779  -12.804 13.505  1   43.761  ? 226  TRP A HA   1 c 
ATOM   3281  H  HB2  . TRP A 1 220 ? 28.117  -11.764 11.399  1   41.011  ? 226  TRP A HB2  1 c 
ATOM   3282  H  HB3  . TRP A 1 220 ? 29.194  -11.339 12.468  1   41.009  ? 226  TRP A HB3  1 c 
ATOM   3283  H  HD1  . TRP A 1 220 ? 31.652  -11.564 11.765  1   43.334  ? 226  TRP A HD1  1 c 
ATOM   3284  H  HE1  . TRP A 1 220 ? 32.864  -12.376 9.855   1   42.692  ? 226  TRP A HE1  1 c 
ATOM   3285  H  HE3  . TRP A 1 220 ? 27.964  -13.802 9.38    1   44.708  ? 226  TRP A HE3  1 c 
ATOM   3286  H  HZ2  . TRP A 1 220 ? 32.299  -13.789 7.545   1   46.594  ? 226  TRP A HZ2  1 c 
ATOM   3287  H  HZ3  . TRP A 1 220 ? 28.393  -14.825 7.344   1   46.143  ? 226  TRP A HZ3  1 c 
ATOM   3288  H  HH2  . TRP A 1 220 ? 30.53   -14.815 6.442   1   47.851  ? 226  TRP A HH2  1 c 
ATOM   3289  N  N    . MET A 1 221 ? 28.254  -15.426 11.77   1   43.433  ? 227  MET A N    1 ? 
ATOM   3290  C  CA   . MET A 1 221 ? 27.63   -16.494 10.99   1   45.303  ? 227  MET A CA   1 ? 
ATOM   3291  C  C    . MET A 1 221 ? 26.531  -17.196 11.793  1   44.471  ? 227  MET A C    1 ? 
ATOM   3292  O  O    . MET A 1 221 ? 25.609  -17.794 11.225  1   42.829  ? 227  MET A O    1 ? 
ATOM   3293  C  CB   . MET A 1 221 ? 28.627  -17.603 10.64   1   52.279  ? 227  MET A CB   1 ? 
ATOM   3294  C  CG   . MET A 1 221 ? 29.477  -17.385 9.411   1   68.527  ? 227  MET A CG   1 ? 
ATOM   3295  S  SD   . MET A 1 221 ? 30.639  -18.752 9.188   1   70.074  ? 227  MET A SD   1 ? 
ATOM   3296  C  CE   . MET A 1 221 ? 31.921  -17.886 8.267   1   70.471  ? 227  MET A CE   1 ? 
ATOM   3297  H  H    . MET A 1 221 ? 29.105  -15.557 12.075  1   43.557  ? 227  MET A H    1 c 
ATOM   3298  H  HA   . MET A 1 221 ? 27.245  -16.108 10.164  1   45.853  ? 227  MET A HA   1 c 
ATOM   3299  H  HB2  . MET A 1 221 ? 29.223  -17.732 11.408  1   53.707  ? 227  MET A HB2  1 c 
ATOM   3300  H  HB3  . MET A 1 221 ? 28.126  -18.438 10.521  1   53.728  ? 227  MET A HB3  1 c 
ATOM   3301  H  HG2  . MET A 1 221 ? 28.904  -17.318 8.621   1   64.446  ? 227  MET A HG2  1 c 
ATOM   3302  H  HG3  . MET A 1 221 ? 29.977  -16.55  9.499   1   64.355  ? 227  MET A HG3  1 c 
ATOM   3303  H  HE1  . MET A 1 221 ? 32.629  -18.511 8.027   1   70.194  ? 227  MET A HE1  1 c 
ATOM   3304  H  HE2  . MET A 1 221 ? 31.537  -17.506 7.456   1   70.26   ? 227  MET A HE2  1 c 
ATOM   3305  H  HE3  . MET A 1 221 ? 32.29   -17.17  8.817   1   69.991  ? 227  MET A HE3  1 c 
ATOM   3306  N  N    . ALA A 1 222 ? 26.732  -17.219 13.118  1   46.928  ? 228  ALA A N    1 ? 
ATOM   3307  C  CA   . ALA A 1 222 ? 25.757  -17.663 14.104  1   42.819  ? 228  ALA A CA   1 ? 
ATOM   3308  C  C    . ALA A 1 222 ? 25.457  -19.165 14.016  1   47.446  ? 228  ALA A C    1 ? 
ATOM   3309  O  O    . ALA A 1 222 ? 24.327  -19.603 14.258  1   48.724  ? 228  ALA A O    1 ? 
ATOM   3310  C  CB   . ALA A 1 222 ? 24.529  -16.788 13.981  1   42.41   ? 228  ALA A CB   1 ? 
ATOM   3311  H  H    . ALA A 1 222 ? 27.547  -16.948 13.428  1   45.36   ? 228  ALA A H    1 c 
ATOM   3312  H  HA   . ALA A 1 222 ? 26.157  -17.5   15.003  1   44.339  ? 228  ALA A HA   1 c 
ATOM   3313  H  HB1  . ALA A 1 222 ? 24.793  -15.853 13.967  1   42.541  ? 228  ALA A HB1  1 c 
ATOM   3314  H  HB2  . ALA A 1 222 ? 24.055  -17     13.158  1   42.549  ? 228  ALA A HB2  1 c 
ATOM   3315  H  HB3  . ALA A 1 222 ? 23.939  -16.944 14.738  1   42.564  ? 228  ALA A HB3  1 c 
ATOM   3316  N  N    . PHE A 1 223 ? 26.484  -19.966 13.689  1   49.449  ? 229  PHE A N    1 ? 
ATOM   3317  C  CA   . PHE A 1 223 ? 26.371  -21.42  13.718  1   49.339  ? 229  PHE A CA   1 ? 
ATOM   3318  C  C    . PHE A 1 223 ? 26.666  -21.952 15.134  1   55.701  ? 229  PHE A C    1 ? 
ATOM   3319  O  O    . PHE A 1 223 ? 26.47   -23.135 15.386  1   53.172  ? 229  PHE A O    1 ? 
ATOM   3320  C  CB   . PHE A 1 223 ? 27.301  -22.039 12.666  1   41.277  ? 229  PHE A CB   1 ? 
ATOM   3321  C  CG   . PHE A 1 223 ? 26.969  -21.737 11.201  1   52.625  ? 229  PHE A CG   1 ? 
ATOM   3322  C  CD1  . PHE A 1 223 ? 25.67   -21.858 10.712  1   53.558  ? 229  PHE A CD1  1 ? 
ATOM   3323  C  CD2  . PHE A 1 223 ? 27.95   -21.313 10.311  1   52.263  ? 229  PHE A CD2  1 ? 
ATOM   3324  C  CE1  . PHE A 1 223 ? 25.386  -21.618 9.376   1   54.962  ? 229  PHE A CE1  1 ? 
ATOM   3325  C  CE2  . PHE A 1 223 ? 27.651  -21.044 8.986   1   53.094  ? 229  PHE A CE2  1 ? 
ATOM   3326  C  CZ   . PHE A 1 223 ? 26.377  -21.206 8.513   1   49.627  ? 229  PHE A CZ   1 ? 
ATOM   3327  H  H    . PHE A 1 223 ? 27.282  -19.594 13.445  1   48.827  ? 229  PHE A H    1 c 
ATOM   3328  H  HA   . PHE A 1 223 ? 25.437  -21.664 13.485  1   48.879  ? 229  PHE A HA   1 c 
ATOM   3329  H  HB2  . PHE A 1 223 ? 28.216  -21.729 12.848  1   45.517  ? 229  PHE A HB2  1 c 
ATOM   3330  H  HB3  . PHE A 1 223 ? 27.297  -23.014 12.791  1   45.494  ? 229  PHE A HB3  1 c 
ATOM   3331  H  HD1  . PHE A 1 223 ? 24.984  -22.16  11.286  1   53.48   ? 229  PHE A HD1  1 c 
ATOM   3332  H  HD2  . PHE A 1 223 ? 28.837  -21.212 10.616  1   52.406  ? 229  PHE A HD2  1 c 
ATOM   3333  H  HE1  . PHE A 1 223 ? 24.5    -21.711 9.063   1   53.295  ? 229  PHE A HE1  1 c 
ATOM   3334  H  HE2  . PHE A 1 223 ? 28.337  -20.768 8.399   1   52.068  ? 229  PHE A HE2  1 c 
ATOM   3335  H  HZ   . PHE A 1 223 ? 26.175  -21.014 7.611   1   51.642  ? 229  PHE A HZ   1 c 
ATOM   3336  N  N    . GLN A 1 224 ? 27.188  -21.103 16.041  1   57.202  ? 230  GLN A N    1 ? 
ATOM   3337  C  CA   . GLN A 1 224 ? 27.411  -21.458 17.441  1   58.771  ? 230  GLN A CA   1 ? 
ATOM   3338  C  C    . GLN A 1 224 ? 26.386  -20.756 18.339  1   63.88   ? 230  GLN A C    1 ? 
ATOM   3339  O  O    . GLN A 1 224 ? 26.533  -20.73  19.555  1   60.674  ? 230  GLN A O    1 ? 
ATOM   3340  C  CB   . GLN A 1 224 ? 28.824  -21.087 17.898  1   60.968  ? 230  GLN A CB   1 ? 
ATOM   3341  C  CG   . GLN A 1 224 ? 29.865  -22.18  17.682  1   69.576  ? 230  GLN A CG   1 ? 
ATOM   3342  C  CD   . GLN A 1 224 ? 30.289  -22.345 16.239  1   73.89   ? 230  GLN A CD   1 ? 
ATOM   3343  O  OE1  . GLN A 1 224 ? 30.164  -21.432 15.42   1   78.95   ? 230  GLN A OE1  1 ? 
ATOM   3344  N  NE2  . GLN A 1 224 ? 30.834  -23.507 15.917  1   84.406  ? 230  GLN A NE2  1 ? 
ATOM   3345  H  H    . GLN A 1 224 ? 27.426  -20.264 15.769  1   57.05   ? 230  GLN A H    1 c 
ATOM   3346  H  HA   . GLN A 1 224 ? 27.295  -22.437 17.54   1   59.796  ? 230  GLN A HA   1 c 
ATOM   3347  H  HB2  . GLN A 1 224 ? 29.106  -20.282 17.416  1   62.329  ? 230  GLN A HB2  1 c 
ATOM   3348  H  HB3  . GLN A 1 224 ? 28.8    -20.865 18.852  1   62.32   ? 230  GLN A HB3  1 c 
ATOM   3349  H  HG2  . GLN A 1 224 ? 30.66   -21.976 18.219  1   68.468  ? 230  GLN A HG2  1 c 
ATOM   3350  H  HG3  . GLN A 1 224 ? 29.504  -23.035 18.001  1   68.479  ? 230  GLN A HG3  1 c 
ATOM   3351  H  HE21 . GLN A 1 224 ? 31.027  -23.684 15.069  1   80.955  ? 230  GLN A HE21 1 c 
ATOM   3352  H  HE22 . GLN A 1 224 ? 31.008  -24.108 16.546  1   80.814  ? 230  GLN A HE22 1 c 
ATOM   3353  N  N    . TRP A 1 225 ? 25.323  -20.202 17.747  1   67.575  ? 231  TRP A N    1 ? 
ATOM   3354  C  CA   . TRP A 1 225 ? 24.408  -19.354 18.495  1   68.043  ? 231  TRP A CA   1 ? 
ATOM   3355  C  C    . TRP A 1 225 ? 23.663  -20.177 19.547  1   64.793  ? 231  TRP A C    1 ? 
ATOM   3356  O  O    . TRP A 1 225 ? 23.27   -21.306 19.287  1   62.775  ? 231  TRP A O    1 ? 
ATOM   3357  C  CB   . TRP A 1 225 ? 23.422  -18.624 17.562  1   64.838  ? 231  TRP A CB   1 ? 
ATOM   3358  C  CG   . TRP A 1 225 ? 22.399  -17.833 18.328  1   59.922  ? 231  TRP A CG   1 ? 
ATOM   3359  C  CD1  . TRP A 1 225 ? 22.515  -16.551 18.782  1   60.848  ? 231  TRP A CD1  1 ? 
ATOM   3360  C  CD2  . TRP A 1 225 ? 21.128  -18.319 18.808  1   67.126  ? 231  TRP A CD2  1 ? 
ATOM   3361  N  NE1  . TRP A 1 225 ? 21.393  -16.187 19.476  1   65.765  ? 231  TRP A NE1  1 ? 
ATOM   3362  C  CE2  . TRP A 1 225 ? 20.529  -17.252 19.522  1   73.872  ? 231  TRP A CE2  1 ? 
ATOM   3363  C  CE3  . TRP A 1 225 ? 20.441  -19.537 18.697  1   70.245  ? 231  TRP A CE3  1 ? 
ATOM   3364  C  CZ2  . TRP A 1 225 ? 19.27   -17.371 20.113  1   76.401  ? 231  TRP A CZ2  1 ? 
ATOM   3365  C  CZ3  . TRP A 1 225 ? 19.201  -19.653 19.284  1   77.935  ? 231  TRP A CZ3  1 ? 
ATOM   3366  C  CH2  . TRP A 1 225 ? 18.629  -18.587 19.99   1   84.115  ? 231  TRP A CH2  1 ? 
ATOM   3367  H  H    . TRP A 1 225 ? 25.156  -20.36  16.863  1   66.562  ? 231  TRP A H    1 c 
ATOM   3368  H  HA   . TRP A 1 225 ? 24.95   -18.663 18.964  1   66.761  ? 231  TRP A HA   1 c 
ATOM   3369  H  HB2  . TRP A 1 225 ? 23.928  -18.017 16.981  1   64.36   ? 231  TRP A HB2  1 c 
ATOM   3370  H  HB3  . TRP A 1 225 ? 22.964  -19.288 17.006  1   64.36   ? 231  TRP A HB3  1 c 
ATOM   3371  H  HD1  . TRP A 1 225 ? 23.251  -15.981 18.621  1   61.89   ? 231  TRP A HD1  1 c 
ATOM   3372  H  HE1  . TRP A 1 225 ? 21.257  -15.406 19.842  1   66.35   ? 231  TRP A HE1  1 c 
ATOM   3373  H  HE3  . TRP A 1 225 ? 20.821  -20.258 18.225  1   71.301  ? 231  TRP A HE3  1 c 
ATOM   3374  H  HZ2  . TRP A 1 225 ? 18.883  -16.657 20.589  1   77.353  ? 231  TRP A HZ2  1 c 
ATOM   3375  H  HZ3  . TRP A 1 225 ? 18.732  -20.469 19.22   1   77.258  ? 231  TRP A HZ3  1 c 
ATOM   3376  H  HH2  . TRP A 1 225 ? 17.781  -18.698 20.381  1   80.431  ? 231  TRP A HH2  1 c 
ATOM   3377  N  N    . LYS A 1 226 ? 23.495  -19.567 20.726  1   70.286  ? 232  LYS A N    1 ? 
ATOM   3378  C  CA   . LYS A 1 226 ? 22.707  -20.079 21.833  1   78.116  ? 232  LYS A CA   1 ? 
ATOM   3379  C  C    . LYS A 1 226 ? 21.966  -18.895 22.452  1   77.629  ? 232  LYS A C    1 ? 
ATOM   3380  O  O    . LYS A 1 226 ? 22.452  -17.765 22.384  1   70.753  ? 232  LYS A O    1 ? 
ATOM   3381  C  CB   . LYS A 1 226 ? 23.637  -20.7   22.884  1   84.433  ? 232  LYS A CB   1 ? 
ATOM   3382  C  CG   . LYS A 1 226 ? 24.488  -21.843 22.36   1   90.18   ? 232  LYS A CG   1 ? 
ATOM   3383  C  CD   . LYS A 1 226 ? 25.231  -22.682 23.396  1   95.97   ? 232  LYS A CD   1 ? 
ATOM   3384  C  CE   . LYS A 1 226 ? 25.948  -23.814 22.696  1   100.294 ? 232  LYS A CE   1 ? 
ATOM   3385  N  NZ   . LYS A 1 226 ? 26.46   -24.862 23.582  1   93.231  ? 232  LYS A NZ   1 ? 
ATOM   3386  H  H    . LYS A 1 226 ? 23.913  -18.764 20.847  1   70.615  ? 232  LYS A H    1 c 
ATOM   3387  H  HA   . LYS A 1 226 ? 22.06   -20.747 21.491  1   77.345  ? 232  LYS A HA   1 c 
ATOM   3388  H  HB2  . LYS A 1 226 ? 24.232  -20.002 23.233  1   84.192  ? 232  LYS A HB2  1 c 
ATOM   3389  H  HB3  . LYS A 1 226 ? 23.094  -21.032 23.631  1   84.221  ? 232  LYS A HB3  1 c 
ATOM   3390  H  HG2  . LYS A 1 226 ? 23.906  -22.438 21.839  1   90.057  ? 232  LYS A HG2  1 c 
ATOM   3391  H  HG3  . LYS A 1 226 ? 25.147  -21.468 21.736  1   89.677  ? 232  LYS A HG3  1 c 
ATOM   3392  H  HD2  . LYS A 1 226 ? 25.885  -22.123 23.869  1   95.593  ? 232  LYS A HD2  1 c 
ATOM   3393  H  HD3  . LYS A 1 226 ? 24.594  -23.05  24.046  1   95.593  ? 232  LYS A HD3  1 c 
ATOM   3394  H  HE2  . LYS A 1 226 ? 25.341  -24.225 22.055  1   97.489  ? 232  LYS A HE2  1 c 
ATOM   3395  H  HE3  . LYS A 1 226 ? 26.696  -23.444 22.193  1   97.566  ? 232  LYS A HE3  1 c 
ATOM   3396  H  HZ1  . LYS A 1 226 ? 25.777  -25.229 24.05   1   95.35   ? 232  LYS A HZ1  1 c 
ATOM   3397  H  HZ2  . LYS A 1 226 ? 27.061  -24.507 24.16   1   95.35   ? 232  LYS A HZ2  1 c 
ATOM   3398  H  HZ3  . LYS A 1 226 ? 26.865  -25.507 23.091  1   95.35   ? 232  LYS A HZ3  1 c 
ATOM   3399  N  N    . PRO A 1 227 ? 20.776  -19.108 23.062  1   75.284  ? 233  PRO A N    1 ? 
ATOM   3400  C  CA   . PRO A 1 227 ? 20.062  -18.047 23.783  1   71.488  ? 233  PRO A CA   1 ? 
ATOM   3401  C  C    . PRO A 1 227 ? 20.966  -17.174 24.642  1   62.544  ? 233  PRO A C    1 ? 
ATOM   3402  O  O    . PRO A 1 227 ? 21.775  -17.699 25.392  1   67.274  ? 233  PRO A O    1 ? 
ATOM   3403  C  CB   . PRO A 1 227 ? 19.077  -18.862 24.635  1   74.404  ? 233  PRO A CB   1 ? 
ATOM   3404  C  CG   . PRO A 1 227 ? 18.712  -20.025 23.732  1   78.862  ? 233  PRO A CG   1 ? 
ATOM   3405  C  CD   . PRO A 1 227 ? 20.026  -20.377 23.042  1   78.778  ? 233  PRO A CD   1 ? 
ATOM   3406  H  HA   . PRO A 1 227 ? 19.563  -17.49  23.135  1   70.854  ? 233  PRO A HA   1 c 
ATOM   3407  H  HB2  . PRO A 1 227 ? 19.505  -19.179 25.465  1   74.61   ? 233  PRO A HB2  1 c 
ATOM   3408  H  HB3  . PRO A 1 227 ? 18.281  -18.327 24.863  1   74.7    ? 233  PRO A HB3  1 c 
ATOM   3409  H  HG2  . PRO A 1 227 ? 18.376  -20.784 24.254  1   77.814  ? 233  PRO A HG2  1 c 
ATOM   3410  H  HG3  . PRO A 1 227 ? 18.032  -19.762 23.077  1   77.814  ? 233  PRO A HG3  1 c 
ATOM   3411  H  HD2  . PRO A 1 227 ? 20.506  -21.079 23.534  1   77.971  ? 233  PRO A HD2  1 c 
ATOM   3412  H  HD3  . PRO A 1 227 ? 19.868  -20.68  22.12   1   77.967  ? 233  PRO A HD3  1 c 
ATOM   3413  N  N    . GLY A 1 228 ? 20.831  -15.847 24.496  1   62.843  ? 234  GLY A N    1 ? 
ATOM   3414  C  CA   . GLY A 1 228 ? 21.628  -14.867 25.221  1   57.672  ? 234  GLY A CA   1 ? 
ATOM   3415  C  C    . GLY A 1 228 ? 22.679  -14.205 24.333  1   63.339  ? 234  GLY A C    1 ? 
ATOM   3416  O  O    . GLY A 1 228 ? 23.133  -13.115 24.652  1   69.403  ? 234  GLY A O    1 ? 
ATOM   3417  H  H    . GLY A 1 228 ? 20.203  -15.537 23.908  1   61.702  ? 234  GLY A H    1 c 
ATOM   3418  H  HA2  . GLY A 1 228 ? 21.027  -14.176 25.586  1   60.117  ? 234  GLY A HA2  1 c 
ATOM   3419  H  HA3  . GLY A 1 228 ? 22.073  -15.31  25.98   1   60.159  ? 234  GLY A HA3  1 c 
ATOM   3420  N  N    . MET A 1 229 ? 23.049  -14.855 23.217  1   73.079  ? 235  MET A N    1 ? 
ATOM   3421  C  CA   . MET A 1 229 ? 24.002  -14.297 22.265  1   76.599  ? 235  MET A CA   1 ? 
ATOM   3422  C  C    . MET A 1 229 ? 23.285  -13.456 21.208  1   78.642  ? 235  MET A C    1 ? 
ATOM   3423  O  O    . MET A 1 229 ? 22.161  -13.763 20.817  1   76.715  ? 235  MET A O    1 ? 
ATOM   3424  C  CB   . MET A 1 229 ? 24.778  -15.404 21.544  1   76.829  ? 235  MET A CB   1 ? 
ATOM   3425  C  CG   . MET A 1 229 ? 25.714  -16.182 22.451  1   79.521  ? 235  MET A CG   1 ? 
ATOM   3426  S  SD   . MET A 1 229 ? 26.469  -17.596 21.621  1   85.689  ? 235  MET A SD   1 ? 
ATOM   3427  C  CE   . MET A 1 229 ? 27.151  -16.982 20.068  1   82.507  ? 235  MET A CE   1 ? 
ATOM   3428  H  H    . MET A 1 229 ? 22.699  -15.681 23.046  1   71.194  ? 235  MET A H    1 c 
ATOM   3429  H  HA   . MET A 1 229 ? 24.637  -13.719 22.758  1   76.218  ? 235  MET A HA   1 c 
ATOM   3430  H  HB2  . MET A 1 229 ? 24.136  -16.026 21.14   1   77.362  ? 235  MET A HB2  1 c 
ATOM   3431  H  HB3  . MET A 1 229 ? 25.3    -14.999 20.819  1   77.444  ? 235  MET A HB3  1 c 
ATOM   3432  H  HG2  . MET A 1 229 ? 26.423  -15.589 22.77   1   79.987  ? 235  MET A HG2  1 c 
ATOM   3433  H  HG3  . MET A 1 229 ? 25.218  -16.503 23.23   1   79.958  ? 235  MET A HG3  1 c 
ATOM   3434  H  HE1  . MET A 1 229 ? 27.588  -17.713 19.593  1   83.267  ? 235  MET A HE1  1 c 
ATOM   3435  H  HE2  . MET A 1 229 ? 26.432  -16.621 19.517  1   83.21   ? 235  MET A HE2  1 c 
ATOM   3436  H  HE3  . MET A 1 229 ? 27.802  -16.28  20.254  1   83.267  ? 235  MET A HE3  1 c 
ATOM   3437  N  N    . ILE A 1 230 ? 23.98   -12.416 20.732  1   79.185  ? 236  ILE A N    1 ? 
ATOM   3438  C  CA   . ILE A 1 230 ? 23.451  -11.468 19.764  1   75.551  ? 236  ILE A CA   1 ? 
ATOM   3439  C  C    . ILE A 1 230 ? 23.647  -12.021 18.356  1   62.193  ? 236  ILE A C    1 ? 
ATOM   3440  O  O    . ILE A 1 230 ? 24.661  -12.655 18.051  1   56.947  ? 236  ILE A O    1 ? 
ATOM   3441  C  CB   . ILE A 1 230 ? 24.122  -10.085 19.921  1   89.611  ? 236  ILE A CB   1 ? 
ATOM   3442  C  CG1  . ILE A 1 230 ? 23.588  -9.334  21.16   1   100.175 ? 236  ILE A CG1  1 ? 
ATOM   3443  C  CG2  . ILE A 1 230 ? 23.986  -9.238  18.649  1   87.911  ? 236  ILE A CG2  1 ? 
ATOM   3444  C  CD1  . ILE A 1 230 ? 24.253  -7.989  21.437  1   101.99  ? 236  ILE A CD1  1 ? 
ATOM   3445  H  H    . ILE A 1 230 ? 24.837  -12.297 21.026  1   78.336  ? 236  ILE A H    1 c 
ATOM   3446  H  HA   . ILE A 1 230 ? 22.493  -11.363 19.929  1   75.591  ? 236  ILE A HA   1 c 
ATOM   3447  H  HB   . ILE A 1 230 ? 25.077  -10.241 20.066  1   88.242  ? 236  ILE A HB   1 c 
ATOM   3448  H  HG12 . ILE A 1 230 ? 22.627  -9.188  21.045  1   98.09   ? 236  ILE A HG12 1 c 
ATOM   3449  H  HG13 . ILE A 1 230 ? 23.708  -9.907  21.945  1   98.09   ? 236  ILE A HG13 1 c 
ATOM   3450  H  HG21 . ILE A 1 230 ? 24.353  -8.352  18.805  1   88.487  ? 236  ILE A HG21 1 c 
ATOM   3451  H  HG22 . ILE A 1 230 ? 23.047  -9.159  18.409  1   88.255  ? 236  ILE A HG22 1 c 
ATOM   3452  H  HG23 . ILE A 1 230 ? 24.471  -9.659  17.92   1   88.217  ? 236  ILE A HG23 1 c 
ATOM   3453  H  HD11 . ILE A 1 230 ? 25.223  -8.089  21.397  1   101.412 ? 236  ILE A HD11 1 c 
ATOM   3454  H  HD12 . ILE A 1 230 ? 23.997  -7.678  22.326  1   101.411 ? 236  ILE A HD12 1 c 
ATOM   3455  H  HD13 . ILE A 1 230 ? 23.967  -7.334  20.772  1   101.278 ? 236  ILE A HD13 1 c 
ATOM   3456  N  N    . ILE A 1 231 ? 22.629  -11.774 17.527  1   55.849  ? 237  ILE A N    1 ? 
ATOM   3457  C  CA   . ILE A 1 231 ? 22.756  -11.744 16.076  1   52.132  ? 237  ILE A CA   1 ? 
ATOM   3458  C  C    . ILE A 1 231 ? 22.241  -10.38  15.621  1   53.604  ? 237  ILE A C    1 ? 
ATOM   3459  O  O    . ILE A 1 231 ? 21.237  -9.889  16.148  1   51.479  ? 237  ILE A O    1 ? 
ATOM   3460  C  CB   . ILE A 1 231 ? 21.957  -12.891 15.429  1   47.734  ? 237  ILE A CB   1 ? 
ATOM   3461  C  CG1  . ILE A 1 231 ? 22.354  -14.268 15.983  1   48.698  ? 237  ILE A CG1  1 ? 
ATOM   3462  C  CG2  . ILE A 1 231 ? 22.083  -12.848 13.913  1   43.97   ? 237  ILE A CG2  1 ? 
ATOM   3463  C  CD1  . ILE A 1 231 ? 21.378  -15.378 15.611  1   53.832  ? 237  ILE A CD1  1 ? 
ATOM   3464  H  H    . ILE A 1 231 ? 21.803  -11.62  17.887  1   56.659  ? 237  ILE A H    1 c 
ATOM   3465  H  HA   . ILE A 1 231 ? 23.698  -11.832 15.833  1   52.248  ? 237  ILE A HA   1 c 
ATOM   3466  H  HB   . ILE A 1 231 ? 21.014  -12.75  15.649  1   47.955  ? 237  ILE A HB   1 c 
ATOM   3467  H  HG12 . ILE A 1 231 ? 23.242  -14.5   15.643  1   49.619  ? 237  ILE A HG12 1 c 
ATOM   3468  H  HG13 . ILE A 1 231 ? 22.41   -14.213 16.959  1   49.689  ? 237  ILE A HG13 1 c 
ATOM   3469  H  HG21 . ILE A 1 231 ? 21.573  -13.576 13.52   1   45.12   ? 237  ILE A HG21 1 c 
ATOM   3470  H  HG22 . ILE A 1 231 ? 23.018  -12.938 13.661  1   45.051  ? 237  ILE A HG22 1 c 
ATOM   3471  H  HG23 . ILE A 1 231 ? 21.741  -12.003 13.579  1   44.99   ? 237  ILE A HG23 1 c 
ATOM   3472  H  HD11 . ILE A 1 231 ? 20.475  -15.122 15.879  1   52.262  ? 237  ILE A HD11 1 c 
ATOM   3473  H  HD12 . ILE A 1 231 ? 21.63   -16.201 16.07   1   52.316  ? 237  ILE A HD12 1 c 
ATOM   3474  H  HD13 . ILE A 1 231 ? 21.398  -15.528 14.647  1   52.187  ? 237  ILE A HD13 1 c 
ATOM   3475  N  N    . ASN A 1 232 ? 22.922  -9.776  14.638  1   43.827  ? 238  ASN A N    1 ? 
ATOM   3476  C  CA   . ASN A 1 232 ? 22.626  -8.404  14.27   1   46.849  ? 238  ASN A CA   1 ? 
ATOM   3477  C  C    . ASN A 1 232 ? 23.029  -8.167  12.81   1   47.092  ? 238  ASN A C    1 ? 
ATOM   3478  O  O    . ASN A 1 232 ? 23.322  -9.138  12.098  1   38.815  ? 238  ASN A O    1 ? 
ATOM   3479  C  CB   . ASN A 1 232 ? 23.342  -7.45   15.221  1   50.47   ? 238  ASN A CB   1 ? 
ATOM   3480  C  CG   . ASN A 1 232 ? 24.85   -7.506  15.083  1   52.243  ? 238  ASN A CG   1 ? 
ATOM   3481  O  OD1  . ASN A 1 232 ? 25.398  -8.123  14.155  1   46.055  ? 238  ASN A OD1  1 ? 
ATOM   3482  N  ND2  . ASN A 1 232 ? 25.538  -6.838  15.993  1   51.604  ? 238  ASN A ND2  1 ? 
ATOM   3483  H  H    . ASN A 1 232 ? 23.58   -10.228 14.192  1   46.761  ? 238  ASN A H    1 c 
ATOM   3484  H  HA   . ASN A 1 232 ? 21.658  -8.253  14.36   1   46.989  ? 238  ASN A HA   1 c 
ATOM   3485  H  HB2  . ASN A 1 232 ? 23.037  -6.537  15.055  1   49.833  ? 238  ASN A HB2  1 c 
ATOM   3486  H  HB3  . ASN A 1 232 ? 23.101  -7.682  16.14   1   49.997  ? 238  ASN A HB3  1 c 
ATOM   3487  H  HD21 . ASN A 1 232 ? 26.42   -6.776  15.923  1   51.778  ? 238  ASN A HD21 1 c 
ATOM   3488  H  HD22 . ASN A 1 232 ? 25.119  -6.452  16.673  1   51.785  ? 238  ASN A HD22 1 c 
ATOM   3489  N  N    . ASN A 1 233 ? 23.175  -6.872  12.465  1   36.262  ? 239  ASN A N    1 ? 
ATOM   3490  C  CA   . ASN A 1 233 ? 23.424  -6.401  11.11   1   41.054  ? 239  ASN A CA   1 ? 
ATOM   3491  C  C    . ASN A 1 233 ? 24.618  -7.117  10.444  1   34.127  ? 239  ASN A C    1 ? 
ATOM   3492  O  O    . ASN A 1 233 ? 24.656  -7.233  9.237   1   38.113  ? 239  ASN A O    1 ? 
ATOM   3493  C  CB   . ASN A 1 233 ? 23.519  -4.876  11.105  1   41.449  ? 239  ASN A CB   1 ? 
ATOM   3494  C  CG   . ASN A 1 233 ? 24.765  -4.333  11.77   1   39.34   ? 239  ASN A CG   1 ? 
ATOM   3495  O  OD1  . ASN A 1 233 ? 25.775  -4.122  11.109  1   46.884  ? 239  ASN A OD1  1 ? 
ATOM   3496  N  ND2  . ASN A 1 233 ? 24.695  -3.98   13.041  1   49.452  ? 239  ASN A ND2  1 ? 
ATOM   3497  H  H    . ASN A 1 233 ? 23.099  -6.242  13.121  1   40.017  ? 239  ASN A H    1 c 
ATOM   3498  H  HA   . ASN A 1 233 ? 22.628  -6.63   10.579  1   38.809  ? 239  ASN A HA   1 c 
ATOM   3499  H  HB2  . ASN A 1 233 ? 23.501  -4.565  10.181  1   40.846  ? 239  ASN A HB2  1 c 
ATOM   3500  H  HB3  . ASN A 1 233 ? 22.734  -4.509  11.557  1   40.834  ? 239  ASN A HB3  1 c 
ATOM   3501  H  HD21 . ASN A 1 233 ? 25.414  -3.66   13.451  1   46.088  ? 239  ASN A HD21 1 c 
ATOM   3502  H  HD22 . ASN A 1 233 ? 23.932  -4.06   13.485  1   46.076  ? 239  ASN A HD22 1 c 
ATOM   3503  N  N    . TRP A 1 234 ? 25.603  -7.563  11.218  1   35.992  ? 240  TRP A N    1 ? 
ATOM   3504  C  CA   . TRP A 1 234 ? 26.805  -8.186  10.691  1   40.412  ? 240  TRP A CA   1 ? 
ATOM   3505  C  C    . TRP A 1 234 ? 26.429  -9.376  9.823   1   34.804  ? 240  TRP A C    1 ? 
ATOM   3506  O  O    . TRP A 1 234 ? 26.962  -9.578  8.726   1   34.827  ? 240  TRP A O    1 ? 
ATOM   3507  C  CB   . TRP A 1 234 ? 27.73   -8.636  11.846  1   37.486  ? 240  TRP A CB   1 ? 
ATOM   3508  C  CG   . TRP A 1 234 ? 28.646  -7.558  12.377  1   41.541  ? 240  TRP A CG   1 ? 
ATOM   3509  C  CD1  . TRP A 1 234 ? 28.292  -6.416  13.048  1   46.036  ? 240  TRP A CD1  1 ? 
ATOM   3510  C  CD2  . TRP A 1 234 ? 30.096  -7.583  12.383  1   44.775  ? 240  TRP A CD2  1 ? 
ATOM   3511  N  NE1  . TRP A 1 234 ? 29.408  -5.701  13.405  1   44.641  ? 240  TRP A NE1  1 ? 
ATOM   3512  C  CE2  . TRP A 1 234 ? 30.523  -6.397  13.019  1   41.084  ? 240  TRP A CE2  1 ? 
ATOM   3513  C  CE3  . TRP A 1 234 ? 31.06   -8.485  11.904  1   41.762  ? 240  TRP A CE3  1 ? 
ATOM   3514  C  CZ2  . TRP A 1 234 ? 31.865  -6.093  13.163  1   43.005  ? 240  TRP A CZ2  1 ? 
ATOM   3515  C  CZ3  . TRP A 1 234 ? 32.387  -8.204  12.093  1   37.533  ? 240  TRP A CZ3  1 ? 
ATOM   3516  C  CH2  . TRP A 1 234 ? 32.776  -7.024  12.71   1   44.234  ? 240  TRP A CH2  1 ? 
ATOM   3517  H  H    . TRP A 1 234 ? 25.534  -7.456  12.123  1   36.593  ? 240  TRP A H    1 c 
ATOM   3518  H  HA   . TRP A 1 234 ? 27.291  -7.521  10.134  1   37.97   ? 240  TRP A HA   1 c 
ATOM   3519  H  HB2  . TRP A 1 234 ? 27.174  -8.971  12.581  1   39.058  ? 240  TRP A HB2  1 c 
ATOM   3520  H  HB3  . TRP A 1 234 ? 28.279  -9.384  11.529  1   39.05   ? 240  TRP A HB3  1 c 
ATOM   3521  H  HD1  . TRP A 1 234 ? 27.405  -6.125  13.194  1   44.586  ? 240  TRP A HD1  1 c 
ATOM   3522  H  HE1  . TRP A 1 234 ? 29.406  -4.931  13.817  1   44.065  ? 240  TRP A HE1  1 c 
ATOM   3523  H  HE3  . TRP A 1 234 ? 30.796  -9.285  11.483  1   41.422  ? 240  TRP A HE3  1 c 
ATOM   3524  H  HZ2  . TRP A 1 234 ? 32.142  -5.313  13.611  1   42.811  ? 240  TRP A HZ2  1 c 
ATOM   3525  H  HZ3  . TRP A 1 234 ? 33.042  -8.796  11.762  1   40.055  ? 240  TRP A HZ3  1 c 
ATOM   3526  H  HH2  . TRP A 1 234 ? 33.693  -6.845  12.807  1   42.274  ? 240  TRP A HH2  1 c 
ATOM   3527  N  N    . ASN A 1 235 ? 25.502  -10.18  10.351  1   33.731  ? 241  ASN A N    1 ? 
ATOM   3528  C  CA   . ASN A 1 235 ? 25.105  -11.409 9.7     1   31.934  ? 241  ASN A CA   1 ? 
ATOM   3529  C  C    . ASN A 1 235 ? 24.634  -11.164 8.274   1   29.453  ? 241  ASN A C    1 ? 
ATOM   3530  O  O    . ASN A 1 235 ? 25.151  -11.749 7.324   1   31.959  ? 241  ASN A O    1 ? 
ATOM   3531  C  CB   . ASN A 1 235 ? 24.106  -12.156 10.57   1   37.081  ? 241  ASN A CB   1 ? 
ATOM   3532  C  CG   . ASN A 1 235 ? 23.601  -13.394 9.886   1   40.559  ? 241  ASN A CG   1 ? 
ATOM   3533  O  OD1  . ASN A 1 235 ? 23.014  -13.285 8.8     1   35.132  ? 241  ASN A OD1  1 ? 
ATOM   3534  N  ND2  . ASN A 1 235 ? 23.827  -14.548 10.498  1   42.473  ? 241  ASN A ND2  1 ? 
ATOM   3535  H  H    . ASN A 1 235 ? 25.11   -9.956  11.146  1   33.647  ? 241  ASN A H    1 c 
ATOM   3536  H  HA   . ASN A 1 235 ? 25.906  -11.977 9.644   1   32.689  ? 241  ASN A HA   1 c 
ATOM   3537  H  HB2  . ASN A 1 235 ? 24.536  -12.404 11.412  1   36.672  ? 241  ASN A HB2  1 c 
ATOM   3538  H  HB3  . ASN A 1 235 ? 23.353  -11.572 10.779  1   36.582  ? 241  ASN A HB3  1 c 
ATOM   3539  H  HD21 . ASN A 1 235 ? 23.517  -15.3   10.143  1   41.854  ? 241  ASN A HD21 1 c 
ATOM   3540  H  HD22 . ASN A 1 235 ? 24.285  -14.573 11.257  1   41.786  ? 241  ASN A HD22 1 c 
ATOM   3541  N  N    . PRO A 1 236 ? 23.543  -10.417 8.02    1   33.171  ? 242  PRO A N    1 ? 
ATOM   3542  C  CA   . PRO A 1 236 ? 23.118  -10.231 6.639   1   25.17   ? 242  PRO A CA   1 ? 
ATOM   3543  C  C    . PRO A 1 236 ? 24.103  -9.421  5.811   1   30.034  ? 242  PRO A C    1 ? 
ATOM   3544  O  O    . PRO A 1 236 ? 24.246  -9.653  4.598   1   33.577  ? 242  PRO A O    1 ? 
ATOM   3545  C  CB   . PRO A 1 236 ? 21.781  -9.533  6.755   1   33.087  ? 242  PRO A CB   1 ? 
ATOM   3546  C  CG   . PRO A 1 236 ? 21.719  -9.009  8.153   1   34.055  ? 242  PRO A CG   1 ? 
ATOM   3547  C  CD   . PRO A 1 236 ? 22.593  -9.887  9.003   1   34.86   ? 242  PRO A CD   1 ? 
ATOM   3548  H  HA   . PRO A 1 236 ? 22.986  -11.119 6.223   1   28.857  ? 242  PRO A HA   1 c 
ATOM   3549  H  HB2  . PRO A 1 236 ? 21.713  -8.795  6.103   1   31.302  ? 242  PRO A HB2  1 c 
ATOM   3550  H  HB3  . PRO A 1 236 ? 21.043  -10.165 6.587   1   31.306  ? 242  PRO A HB3  1 c 
ATOM   3551  H  HG2  . PRO A 1 236 ? 22.037  -8.083  8.184   1   34.011  ? 242  PRO A HG2  1 c 
ATOM   3552  H  HG3  . PRO A 1 236 ? 20.796  -9.028  8.483   1   34.011  ? 242  PRO A HG3  1 c 
ATOM   3553  H  HD2  . PRO A 1 236 ? 23.049  -9.367  9.697   1   34.315  ? 242  PRO A HD2  1 c 
ATOM   3554  H  HD3  . PRO A 1 236 ? 22.069  -10.606 9.419   1   34.316  ? 242  PRO A HD3  1 c 
ATOM   3555  N  N    . TRP A 1 237 ? 24.764  -8.46   6.485   1   31.77   ? 243  TRP A N    1 ? 
ATOM   3556  C  CA   . TRP A 1 237 ? 25.739  -7.623  5.812   1   30.809  ? 243  TRP A CA   1 ? 
ATOM   3557  C  C    . TRP A 1 237 ? 26.921  -8.463  5.323   1   30.57   ? 243  TRP A C    1 ? 
ATOM   3558  O  O    . TRP A 1 237 ? 27.178  -8.488  4.117   1   31.466  ? 243  TRP A O    1 ? 
ATOM   3559  C  CB   . TRP A 1 237 ? 26.128  -6.462  6.715   1   29.74   ? 243  TRP A CB   1 ? 
ATOM   3560  C  CG   . TRP A 1 237 ? 26.932  -5.379  6.056   1   33.917  ? 243  TRP A CG   1 ? 
ATOM   3561  C  CD1  . TRP A 1 237 ? 27.531  -5.354  4.821   1   36.068  ? 243  TRP A CD1  1 ? 
ATOM   3562  C  CD2  . TRP A 1 237 ? 27.314  -4.161  6.713   1   30.304  ? 243  TRP A CD2  1 ? 
ATOM   3563  N  NE1  . TRP A 1 237 ? 28.24   -4.186  4.668   1   35.336  ? 243  TRP A NE1  1 ? 
ATOM   3564  C  CE2  . TRP A 1 237 ? 28.119  -3.439  5.805   1   30.61   ? 243  TRP A CE2  1 ? 
ATOM   3565  C  CE3  . TRP A 1 237 ? 27.042  -3.621  7.972   1   31.03   ? 243  TRP A CE3  1 ? 
ATOM   3566  C  CZ2  . TRP A 1 237 ? 28.672  -2.207  6.132   1   32.419  ? 243  TRP A CZ2  1 ? 
ATOM   3567  C  CZ3  . TRP A 1 237 ? 27.543  -2.377  8.273   1   30.119  ? 243  TRP A CZ3  1 ? 
ATOM   3568  C  CH2  . TRP A 1 237 ? 28.363  -1.696  7.375   1   32.243  ? 243  TRP A CH2  1 ? 
ATOM   3569  H  H    . TRP A 1 237 ? 24.597  -8.323  7.373   1   31.09   ? 243  TRP A H    1 c 
ATOM   3570  H  HA   . TRP A 1 237 ? 25.295  -7.236  5.011   1   30.753  ? 243  TRP A HA   1 c 
ATOM   3571  H  HB2  . TRP A 1 237 ? 25.307  -6.064  7.076   1   30.952  ? 243  TRP A HB2  1 c 
ATOM   3572  H  HB3  . TRP A 1 237 ? 26.64   -6.817  7.473   1   30.947  ? 243  TRP A HB3  1 c 
ATOM   3573  H  HD1  . TRP A 1 237 ? 27.468  -6.025  4.163   1   35.219  ? 243  TRP A HD1  1 c 
ATOM   3574  H  HE1  . TRP A 1 237 ? 28.682  -3.953  3.952   1   34.283  ? 243  TRP A HE1  1 c 
ATOM   3575  H  HE3  . TRP A 1 237 ? 26.485  -4.078  8.579   1   30.775  ? 243  TRP A HE3  1 c 
ATOM   3576  H  HZ2  . TRP A 1 237 ? 29.206  -1.73   5.519   1   31.953  ? 243  TRP A HZ2  1 c 
ATOM   3577  H  HZ3  . TRP A 1 237 ? 27.379  -2.004  9.123   1   30.837  ? 243  TRP A HZ3  1 c 
ATOM   3578  H  HH2  . TRP A 1 237 ? 28.711  -0.857  7.621   1   31.768  ? 243  TRP A HH2  1 c 
ATOM   3579  N  N    . CYS A 1 238 ? 27.565  -9.222  6.219   1   31.529  ? 244  CYS A N    1 ? 
ATOM   3580  C  CA   . CYS A 1 238 ? 28.667  -10.075 5.804   1   32.916  ? 244  CYS A CA   1 ? 
ATOM   3581  C  C    . CYS A 1 238 ? 28.186  -11.081 4.771   1   32.533  ? 244  CYS A C    1 ? 
ATOM   3582  O  O    . CYS A 1 238 ? 28.829  -11.299 3.738   1   35.347  ? 244  CYS A O    1 ? 
ATOM   3583  C  CB   . CYS A 1 238 ? 29.405  -10.656 7.013   1   34.197  ? 244  CYS A CB   1 ? 
ATOM   3584  S  SG   . CYS A 1 238 ? 30.378  -9.379  7.865   1   39.725  ? 244  CYS A SG   1 ? 
ATOM   3585  H  H    . CYS A 1 238 ? 27.315  -9.207  7.098   1   31.652  ? 244  CYS A H    1 c 
ATOM   3586  H  HA   . CYS A 1 238 ? 29.327  -9.489  5.352   1   32.817  ? 244  CYS A HA   1 c 
ATOM   3587  H  HB2  . CYS A 1 238 ? 28.756  -11.04  7.643   1   34.838  ? 244  CYS A HB2  1 c 
ATOM   3588  H  HB3  . CYS A 1 238 ? 30.009  -11.372 6.716   1   34.856  ? 244  CYS A HB3  1 c 
ATOM   3589  H  HG   . CYS A 1 238 ? 30.838  -10.066 8.74    0   39.57   ? 244  CYS A HG   1 c 
ATOM   3590  N  N    . ASN A 1 239 ? 27.044  -11.711 5.04    1   36.39   ? 245  ASN A N    1 ? 
ATOM   3591  C  CA   . ASN A 1 239 ? 26.601  -12.743 4.126   1   31.792  ? 245  ASN A CA   1 ? 
ATOM   3592  C  C    . ASN A 1 239 ? 26.327  -12.171 2.741   1   30.776  ? 245  ASN A C    1 ? 
ATOM   3593  O  O    . ASN A 1 239 ? 26.534  -12.892 1.752   1   26.882  ? 245  ASN A O    1 ? 
ATOM   3594  C  CB   . ASN A 1 239 ? 25.433  -13.545 4.672   1   30.925  ? 245  ASN A CB   1 ? 
ATOM   3595  C  CG   . ASN A 1 239 ? 25.858  -14.653 5.605   1   32.328  ? 245  ASN A CG   1 ? 
ATOM   3596  O  OD1  . ASN A 1 239 ? 26.563  -15.607 5.208   1   32.762  ? 245  ASN A OD1  1 ? 
ATOM   3597  N  ND2  . ASN A 1 239 ? 25.368  -14.592 6.832   1   33.434  ? 245  ASN A ND2  1 ? 
ATOM   3598  H  H    . ASN A 1 239 ? 26.549  -11.51  5.782   1   34.297  ? 245  ASN A H    1 c 
ATOM   3599  H  HA   . ASN A 1 239 ? 27.348  -13.377 4.026   1   32.254  ? 245  ASN A HA   1 c 
ATOM   3600  H  HB2  . ASN A 1 239 ? 24.826  -12.942 5.144   1   31.484  ? 245  ASN A HB2  1 c 
ATOM   3601  H  HB3  . ASN A 1 239 ? 24.94   -13.937 3.924   1   31.445  ? 245  ASN A HB3  1 c 
ATOM   3602  H  HD21 . ASN A 1 239 ? 25.666  -15.152 7.452   1   33.088  ? 245  ASN A HD21 1 c 
ATOM   3603  H  HD22 . ASN A 1 239 ? 24.745  -13.996 7.04    1   33.059  ? 245  ASN A HD22 1 c 
ATOM   3604  N  N    . SER A 1 240 ? 25.768  -10.947 2.648   1   30.597  ? 246  SER A N    1 ? 
ATOM   3605  C  CA   . SER A 1 240 ? 25.417  -10.402 1.347   1   29.328  ? 246  SER A CA   1 ? 
ATOM   3606  C  C    . SER A 1 240 ? 26.658  -10.262 0.477   1   30.448  ? 246  SER A C    1 ? 
ATOM   3607  O  O    . SER A 1 240 ? 26.618  -10.464 -0.758  1   33.028  ? 246  SER A O    1 ? 
ATOM   3608  C  CB   . SER A 1 240 ? 24.622  -9.065  1.436   1   29.213  ? 246  SER A CB   1 ? 
ATOM   3609  O  OG   . SER A 1 240 ? 25.444  -7.977  1.84    1   33.356  ? 246  SER A OG   1 ? 
ATOM   3610  H  H    . SER A 1 240 ? 25.602  -10.455 3.4     1   30.389  ? 246  SER A H    1 c 
ATOM   3611  H  HA   . SER A 1 240 ? 24.828  -11.063 0.905   1   29.756  ? 246  SER A HA   1 c 
ATOM   3612  H  HB2  . SER A 1 240 ? 24.232  -8.866  0.563   1   30.191  ? 246  SER A HB2  1 c 
ATOM   3613  H  HB3  . SER A 1 240 ? 23.892  -9.168  2.073   1   30.213  ? 246  SER A HB3  1 c 
ATOM   3614  H  HG   . SER A 1 240 ? 25.016  -7.27   1.852   0   32.75   ? 246  SER A HG   1 c 
ATOM   3615  N  N    . ASN A 1 241 ? 27.756  -9.855  1.125   1   32.403  ? 247  ASN A N    1 ? 
ATOM   3616  C  CA   . ASN A 1 241 ? 29.002  -9.652  0.418   1   30.854  ? 247  ASN A CA   1 ? 
ATOM   3617  C  C    . ASN A 1 241 ? 29.608  -10.985 -0.019  1   32.414  ? 247  ASN A C    1 ? 
ATOM   3618  O  O    . ASN A 1 241 ? 30.04   -11.129 -1.175  1   29.07   ? 247  ASN A O    1 ? 
ATOM   3619  C  CB   . ASN A 1 241 ? 30.001  -8.881  1.257   1   31.628  ? 247  ASN A CB   1 ? 
ATOM   3620  C  CG   . ASN A 1 241 ? 29.688  -7.415  1.268   1   30.497  ? 247  ASN A CG   1 ? 
ATOM   3621  O  OD1  . ASN A 1 241 ? 29.552  -6.812  0.2     1   31.718  ? 247  ASN A OD1  1 ? 
ATOM   3622  N  ND2  . ASN A 1 241 ? 29.693  -6.806  2.443   1   32.007  ? 247  ASN A ND2  1 ? 
ATOM   3623  H  H    . ASN A 1 241 ? 27.724  -9.692  2.024   1   31.546  ? 247  ASN A H    1 c 
ATOM   3624  H  HA   . ASN A 1 241 ? 28.815  -9.12   -0.388  1   31.573  ? 247  ASN A HA   1 c 
ATOM   3625  H  HB2  . ASN A 1 241 ? 29.987  -9.223  2.173   1   31.197  ? 247  ASN A HB2  1 c 
ATOM   3626  H  HB3  . ASN A 1 241 ? 30.899  -9.016  0.895   1   31.19   ? 247  ASN A HB3  1 c 
ATOM   3627  H  HD21 . ASN A 1 241 ? 29.333  -5.998  2.521   1   31.535  ? 247  ASN A HD21 1 c 
ATOM   3628  H  HD22 . ASN A 1 241 ? 30.055  -7.201  3.151   1   31.532  ? 247  ASN A HD22 1 c 
ATOM   3629  N  N    . VAL A 1 242 ? 29.587  -11.958 0.888   1   31.772  ? 248  VAL A N    1 ? 
ATOM   3630  C  CA   . VAL A 1 242 ? 30.052  -13.289 0.557   1   33.634  ? 248  VAL A CA   1 ? 
ATOM   3631  C  C    . VAL A 1 242 ? 29.308  -13.843 -0.647  1   33.397  ? 248  VAL A C    1 ? 
ATOM   3632  O  O    . VAL A 1 242 ? 29.953  -14.364 -1.552  1   36.721  ? 248  VAL A O    1 ? 
ATOM   3633  C  CB   . VAL A 1 242 ? 30.063  -14.287 1.712   1   34.444  ? 248  VAL A CB   1 ? 
ATOM   3634  C  CG1  . VAL A 1 242 ? 30.406  -15.69  1.232   1   42.018  ? 248  VAL A CG1  1 ? 
ATOM   3635  C  CG2  . VAL A 1 242 ? 31.076  -13.859 2.734   1   34.013  ? 248  VAL A CG2  1 ? 
ATOM   3636  H  H    . VAL A 1 242 ? 29.28   -11.791 1.733   1   32.34   ? 248  VAL A H    1 c 
ATOM   3637  H  HA   . VAL A 1 242 ? 30.983  -13.186 0.279   1   33.372  ? 248  VAL A HA   1 c 
ATOM   3638  H  HB   . VAL A 1 242 ? 29.166  -14.29  2.121   1   35.488  ? 248  VAL A HB   1 c 
ATOM   3639  H  HG11 . VAL A 1 242 ? 31.237  -15.668 0.727   1   39.584  ? 248  VAL A HG11 1 c 
ATOM   3640  H  HG12 . VAL A 1 242 ? 29.692  -16.027 0.665   1   39.535  ? 248  VAL A HG12 1 c 
ATOM   3641  H  HG13 . VAL A 1 242 ? 30.51   -16.274 1.997   1   39.506  ? 248  VAL A HG13 1 c 
ATOM   3642  H  HG21 . VAL A 1 242 ? 31.059  -14.475 3.486   1   34.144  ? 248  VAL A HG21 1 c 
ATOM   3643  H  HG22 . VAL A 1 242 ? 30.867  -12.963 3.046   1   34.117  ? 248  VAL A HG22 1 c 
ATOM   3644  H  HG23 . VAL A 1 242 ? 31.963  -13.863 2.335   1   34.132  ? 248  VAL A HG23 1 c 
ATOM   3645  N  N    . LEU A 1 243 ? 27.994  -13.644 -0.709  1   33.639  ? 249  LEU A N    1 ? 
ATOM   3646  C  CA   . LEU A 1 243 ? 27.188  -14.224 -1.766  1   31.723  ? 249  LEU A CA   1 ? 
ATOM   3647  C  C    . LEU A 1 243 ? 27.562  -13.598 -3.12   1   32.823  ? 249  LEU A C    1 ? 
ATOM   3648  O  O    . LEU A 1 243 ? 27.752  -14.296 -4.095  1   30.027  ? 249  LEU A O    1 ? 
ATOM   3649  C  CB   . LEU A 1 243 ? 25.704  -14.078 -1.458  1   29.673  ? 249  LEU A CB   1 ? 
ATOM   3650  C  CG   . LEU A 1 243 ? 24.764  -14.628 -2.524  1   29.182  ? 249  LEU A CG   1 ? 
ATOM   3651  C  CD1  . LEU A 1 243 ? 25.104  -16.083 -2.808  1   31.781  ? 249  LEU A CD1  1 ? 
ATOM   3652  C  CD2  . LEU A 1 243 ? 23.297  -14.412 -2.114  1   33.027  ? 249  LEU A CD2  1 ? 
ATOM   3653  H  H    . LEU A 1 243 ? 27.584  -13.134 -0.07   1   33.108  ? 249  LEU A H    1 c 
ATOM   3654  H  HA   . LEU A 1 243 ? 27.407  -15.189 -1.809  1   31.918  ? 249  LEU A HA   1 c 
ATOM   3655  H  HB2  . LEU A 1 243 ? 25.518  -14.54  -0.609  1   30.015  ? 249  LEU A HB2  1 c 
ATOM   3656  H  HB3  . LEU A 1 243 ? 25.507  -13.121 -1.333  1   30.015  ? 249  LEU A HB3  1 c 
ATOM   3657  H  HG   . LEU A 1 243 ? 24.918  -14.119 -3.36   1   30.476  ? 249  LEU A HG   1 c 
ATOM   3658  H  HD11 . LEU A 1 243 ? 25.917  -16.131 -3.338  1   30.994  ? 249  LEU A HD11 1 c 
ATOM   3659  H  HD12 . LEU A 1 243 ? 24.374  -16.497 -3.298  1   30.989  ? 249  LEU A HD12 1 c 
ATOM   3660  H  HD13 . LEU A 1 243 ? 25.237  -16.555 -1.968  1   30.984  ? 249  LEU A HD13 1 c 
ATOM   3661  H  HD21 . LEU A 1 243 ? 23.144  -13.469 -1.935  1   31.876  ? 249  LEU A HD21 1 c 
ATOM   3662  H  HD22 . LEU A 1 243 ? 23.104  -14.928 -1.312  1   31.866  ? 249  LEU A HD22 1 c 
ATOM   3663  H  HD23 . LEU A 1 243 ? 22.711  -14.704 -2.833  1   31.86   ? 249  LEU A HD23 1 c 
ATOM   3664  N  N    . GLN A 1 244 ? 27.69   -12.278 -3.188  1   30.934  ? 250  GLN A N    1 ? 
ATOM   3665  C  CA   . GLN A 1 244 ? 28.106  -11.634 -4.435  1   29.087  ? 250  GLN A CA   1 ? 
ATOM   3666  C  C    . GLN A 1 244 ? 29.404  -12.271 -4.948  1   30.002  ? 250  GLN A C    1 ? 
ATOM   3667  O  O    . GLN A 1 244 ? 29.458  -12.687 -6.075  1   32.529  ? 250  GLN A O    1 ? 
ATOM   3668  C  CB   . GLN A 1 244 ? 28.342  -10.137 -4.268  1   26.561  ? 250  GLN A CB   1 ? 
ATOM   3669  C  CG   . GLN A 1 244 ? 27.161  -9.294  -3.76   1   29.555  ? 250  GLN A CG   1 ? 
ATOM   3670  C  CD   . GLN A 1 244 ? 27.486  -7.802  -3.695  1   32.624  ? 250  GLN A CD   1 ? 
ATOM   3671  O  OE1  . GLN A 1 244 ? 27.762  -7.16   -4.712  1   36.896  ? 250  GLN A OE1  1 ? 
ATOM   3672  N  NE2  . GLN A 1 244 ? 27.503  -7.191  -2.526  1   31.116  ? 250  GLN A NE2  1 ? 
ATOM   3673  H  H    . GLN A 1 244 ? 27.519  -11.763 -2.453  1   30.919  ? 250  GLN A H    1 c 
ATOM   3674  H  HA   . GLN A 1 244 ? 27.394  -11.774 -5.11   1   29.134  ? 250  GLN A HA   1 c 
ATOM   3675  H  HB2  . GLN A 1 244 ? 29.092  -10.019 -3.649  1   27.8    ? 250  GLN A HB2  1 c 
ATOM   3676  H  HB3  . GLN A 1 244 ? 28.624  -9.779  -5.135  1   27.799  ? 250  GLN A HB3  1 c 
ATOM   3677  H  HG2  . GLN A 1 244 ? 26.391  -9.423  -4.354  1   29.522  ? 250  GLN A HG2  1 c 
ATOM   3678  H  HG3  . GLN A 1 244 ? 26.903  -9.601  -2.868  1   29.57   ? 250  GLN A HG3  1 c 
ATOM   3679  H  HE21 . GLN A 1 244 ? 27.841  -6.373  -2.459  1   31.583  ? 250  GLN A HE21 1 c 
ATOM   3680  H  HE22 . GLN A 1 244 ? 27.177  -7.596  -1.807  1   31.544  ? 250  GLN A HE22 1 c 
ATOM   3681  N  N    . CYS A 1 245 ? 30.419  -12.394 -4.077  1   35.016  ? 251  CYS A N    1 ? 
ATOM   3682  C  CA   . CYS A 1 245 ? 31.705  -12.98  -4.406  1   37.565  ? 251  CYS A CA   1 ? 
ATOM   3683  C  C    . CYS A 1 245 ? 31.539  -14.376 -5.019  1   32.813  ? 251  CYS A C    1 ? 
ATOM   3684  O  O    . CYS A 1 245 ? 32.112  -14.654 -6.081  1   33.854  ? 251  CYS A O    1 ? 
ATOM   3685  C  CB   . CYS A 1 245 ? 32.667  -12.936 -3.211  1   36.514  ? 251  CYS A CB   1 ? 
ATOM   3686  S  SG   . CYS A 1 245 ? 33.151  -11.282 -2.62   1   32.171  ? 251  CYS A SG   1 ? 
ATOM   3687  H  H    . CYS A 1 245 ? 30.295  -12.085 -3.226  1   34.25   ? 251  CYS A H    1 c 
ATOM   3688  H  HA   . CYS A 1 245 ? 32.115  -12.402 -5.099  1   35.946  ? 251  CYS A HA   1 c 
ATOM   3689  H  HB2  . CYS A 1 245 ? 32.253  -13.415 -2.459  1   35.894  ? 251  CYS A HB2  1 c 
ATOM   3690  H  HB3  . CYS A 1 245 ? 33.487  -13.421 -3.453  1   35.891  ? 251  CYS A HB3  1 c 
ATOM   3691  H  HG   . CYS A 1 245 ? 33.779  -11.582 -1.74   0   32.3    ? 251  CYS A HG   1 c 
ATOM   3692  N  N    . TYR A 1 246 ? 30.745  -15.249 -4.379  1   31.881  ? 252  TYR A N    1 ? 
ATOM   3693  C  CA   . TYR A 1 246 ? 30.493  -16.597 -4.91   1   33.892  ? 252  TYR A CA   1 ? 
ATOM   3694  C  C    . TYR A 1 246 ? 29.8    -16.568 -6.272  1   36.657  ? 252  TYR A C    1 ? 
ATOM   3695  O  O    . TYR A 1 246 ? 30.219  -17.285 -7.186  1   32.378  ? 252  TYR A O    1 ? 
ATOM   3696  C  CB   . TYR A 1 246 ? 29.725  -17.501 -3.944  1   34.005  ? 252  TYR A CB   1 ? 
ATOM   3697  C  CG   . TYR A 1 246 ? 30.69   -18.235 -3.022  1   34.208  ? 252  TYR A CG   1 ? 
ATOM   3698  C  CD1  . TYR A 1 246 ? 31.418  -19.324 -3.477  1   33.123  ? 252  TYR A CD1  1 ? 
ATOM   3699  C  CD2  . TYR A 1 246 ? 30.873  -17.846 -1.703  1   37.337  ? 252  TYR A CD2  1 ? 
ATOM   3700  C  CE1  . TYR A 1 246 ? 32.305  -20.003 -2.657  1   35.612  ? 252  TYR A CE1  1 ? 
ATOM   3701  C  CE2  . TYR A 1 246 ? 31.778  -18.491 -0.878  1   34.155  ? 252  TYR A CE2  1 ? 
ATOM   3702  C  CZ   . TYR A 1 246 ? 32.496  -19.576 -1.358  1   36.31   ? 252  TYR A CZ   1 ? 
ATOM   3703  O  OH   . TYR A 1 246 ? 33.352  -20.257 -0.542  1   37.865  ? 252  TYR A OH   1 ? 
ATOM   3704  H  H    . TYR A 1 246 ? 30.35   -15.004 -3.592  1   32.608  ? 252  TYR A H    1 c 
ATOM   3705  H  HA   . TYR A 1 246 ? 31.383  -17.016 -5.051  1   33.983  ? 252  TYR A HA   1 c 
ATOM   3706  H  HB2  . TYR A 1 246 ? 29.111  -16.953 -3.408  1   34.018  ? 252  TYR A HB2  1 c 
ATOM   3707  H  HB3  . TYR A 1 246 ? 29.204  -18.155 -4.459  1   34.035  ? 252  TYR A HB3  1 c 
ATOM   3708  H  HD1  . TYR A 1 246 ? 31.304  -19.613 -4.368  1   34.008  ? 252  TYR A HD1  1 c 
ATOM   3709  H  HD2  . TYR A 1 246 ? 30.404  -17.096 -1.374  1   35.833  ? 252  TYR A HD2  1 c 
ATOM   3710  H  HE1  . TYR A 1 246 ? 32.79   -20.739 -2.99   1   35.184  ? 252  TYR A HE1  1 c 
ATOM   3711  H  HE2  . TYR A 1 246 ? 31.886  -18.212 0.015   1   35.368  ? 252  TYR A HE2  1 c 
ATOM   3712  H  HH   . TYR A 1 246 ? 34.15   -19.927 -0.617  0   37.62   ? 252  TYR A HH   1 c 
ATOM   3713  N  N    . LEU A 1 247 ? 28.777  -15.714 -6.421  1   31.996  ? 253  LEU A N    1 ? 
ATOM   3714  C  CA   . LEU A 1 247 ? 28.017  -15.623 -7.668  1   34.162  ? 253  LEU A CA   1 ? 
ATOM   3715  C  C    . LEU A 1 247 ? 28.866  -15.073 -8.803  1   30.399  ? 253  LEU A C    1 ? 
ATOM   3716  O  O    . LEU A 1 247 ? 28.616  -15.385 -9.973  1   27.225  ? 253  LEU A O    1 ? 
ATOM   3717  C  CB   . LEU A 1 247 ? 26.733  -14.792 -7.505  1   31.59   ? 253  LEU A CB   1 ? 
ATOM   3718  C  CG   . LEU A 1 247 ? 25.625  -15.443 -6.672  1   28.224  ? 253  LEU A CG   1 ? 
ATOM   3719  C  CD1  . LEU A 1 247 ? 24.386  -14.549 -6.567  1   28.625  ? 253  LEU A CD1  1 ? 
ATOM   3720  C  CD2  . LEU A 1 247 ? 25.186  -16.801 -7.212  1   25.728  ? 253  LEU A CD2  1 ? 
ATOM   3721  H  H    . LEU A 1 247 ? 28.542  -15.172 -5.724  1   33.52   ? 253  LEU A H    1 c 
ATOM   3722  H  HA   . LEU A 1 247 ? 27.761  -16.545 -7.921  1   32.473  ? 253  LEU A HA   1 c 
ATOM   3723  H  HB2  . LEU A 1 247 ? 26.973  -13.932 -7.089  1   31.341  ? 253  LEU A HB2  1 c 
ATOM   3724  H  HB3  . LEU A 1 247 ? 26.373  -14.608 -8.401  1   31.339  ? 253  LEU A HB3  1 c 
ATOM   3725  H  HG   . LEU A 1 247 ? 25.975  -15.582 -5.754  1   28.4    ? 253  LEU A HG   1 c 
ATOM   3726  H  HD11 . LEU A 1 247 ? 24.633  -13.699 -6.164  1   28.503  ? 253  LEU A HD11 1 c 
ATOM   3727  H  HD12 . LEU A 1 247 ? 23.716  -14.984 -6.014  1   28.492  ? 253  LEU A HD12 1 c 
ATOM   3728  H  HD13 . LEU A 1 247 ? 24.022  -14.392 -7.454  1   28.503  ? 253  LEU A HD13 1 c 
ATOM   3729  H  HD21 . LEU A 1 247 ? 25.903  -17.446 -7.093  1   26.565  ? 253  LEU A HD21 1 c 
ATOM   3730  H  HD22 . LEU A 1 247 ? 24.975  -16.722 -8.157  1   26.473  ? 253  LEU A HD22 1 c 
ATOM   3731  H  HD23 . LEU A 1 247 ? 24.399  -17.104 -6.73   1   26.493  ? 253  LEU A HD23 1 c 
ATOM   3732  N  N    . LEU A 1 248 ? 29.86   -14.241 -8.485  1   30.152  ? 254  LEU A N    1 ? 
ATOM   3733  C  CA   . LEU A 1 248 ? 30.696  -13.656 -9.523  1   29.453  ? 254  LEU A CA   1 ? 
ATOM   3734  C  C    . LEU A 1 248 ? 31.917  -14.513 -9.871  1   29.167  ? 254  LEU A C    1 ? 
ATOM   3735  O  O    . LEU A 1 248 ? 32.449  -14.358 -10.968 1   29.109  ? 254  LEU A O    1 ? 
ATOM   3736  C  CB   . LEU A 1 248 ? 31.147  -12.274 -9.055  1   31.482  ? 254  LEU A CB   1 ? 
ATOM   3737  C  CG   . LEU A 1 248 ? 30.104  -11.161 -9.196  1   32.942  ? 254  LEU A CG   1 ? 
ATOM   3738  C  CD1  . LEU A 1 248 ? 30.5    -9.946  -8.389  1   33.61   ? 254  LEU A CD1  1 ? 
ATOM   3739  C  CD2  . LEU A 1 248 ? 29.877  -10.793 -10.67  1   32.793  ? 254  LEU A CD2  1 ? 
ATOM   3740  H  H    . LEU A 1 248 ? 30.018  -14.028 -7.611  1   30.141  ? 254  LEU A H    1 c 
ATOM   3741  H  HA   . LEU A 1 248 ? 30.149  -13.553 -10.341 1   29.914  ? 254  LEU A HA   1 c 
ATOM   3742  H  HB2  . LEU A 1 248 ? 31.411  -12.339 -8.108  1   31.334  ? 254  LEU A HB2  1 c 
ATOM   3743  H  HB3  . LEU A 1 248 ? 31.946  -12.019 -9.572  1   31.316  ? 254  LEU A HB3  1 c 
ATOM   3744  H  HG   . LEU A 1 248 ? 29.245  -11.498 -8.832  1   32.763  ? 254  LEU A HG   1 c 
ATOM   3745  H  HD11 . LEU A 1 248 ? 30.665  -10.207 -7.467  1   33.382  ? 254  LEU A HD11 1 c 
ATOM   3746  H  HD12 . LEU A 1 248 ? 29.783  -9.293  -8.415  1   33.351  ? 254  LEU A HD12 1 c 
ATOM   3747  H  HD13 . LEU A 1 248 ? 31.307  -9.555  -8.764  1   33.394  ? 254  LEU A HD13 1 c 
ATOM   3748  H  HD21 . LEU A 1 248 ? 29.531  -11.564 -11.149 1   32.797  ? 254  LEU A HD21 1 c 
ATOM   3749  H  HD22 . LEU A 1 248 ? 30.718  -10.516 -11.068 1   32.856  ? 254  LEU A HD22 1 c 
ATOM   3750  H  HD23 . LEU A 1 248 ? 29.237  -10.064 -10.728 1   32.802  ? 254  LEU A HD23 1 c 
ATOM   3751  N  N    . LEU A 1 249 ? 32.417  -15.35  -8.948  1   32.872  ? 255  LEU A N    1 ? 
ATOM   3752  C  CA   . LEU A 1 249 ? 33.703  -16.009 -9.155  1   34.918  ? 255  LEU A CA   1 ? 
ATOM   3753  C  C    . LEU A 1 249 ? 33.654  -17.542 -9.242  1   40.501  ? 255  LEU A C    1 ? 
ATOM   3754  O  O    . LEU A 1 249 ? 34.586  -18.148 -9.828  1   36.17   ? 255  LEU A O    1 ? 
ATOM   3755  C  CB   . LEU A 1 249 ? 34.591  -15.607 -7.992  1   35.044  ? 255  LEU A CB   1 ? 
ATOM   3756  C  CG   . LEU A 1 249 ? 34.808  -14.111 -7.793  1   32.128  ? 255  LEU A CG   1 ? 
ATOM   3757  C  CD1  . LEU A 1 249 ? 35.653  -13.928 -6.549  1   36.557  ? 255  LEU A CD1  1 ? 
ATOM   3758  C  CD2  . LEU A 1 249 ? 35.464  -13.462 -8.957  1   33.138  ? 255  LEU A CD2  1 ? 
ATOM   3759  H  H    . LEU A 1 249 ? 31.957  -15.504 -8.174  1   32.408  ? 255  LEU A H    1 c 
ATOM   3760  H  HA   . LEU A 1 249 ? 34.1    -15.667 -9.993  1   35.384  ? 255  LEU A HA   1 c 
ATOM   3761  H  HB2  . LEU A 1 249 ? 34.2    -15.976 -7.167  1   34.35   ? 255  LEU A HB2  1 c 
ATOM   3762  H  HB3  . LEU A 1 249 ? 35.471  -16.033 -8.118  1   34.362  ? 255  LEU A HB3  1 c 
ATOM   3763  H  HG   . LEU A 1 249 ? 33.928  -13.679 -7.644  1   33.629  ? 255  LEU A HG   1 c 
ATOM   3764  H  HD11 . LEU A 1 249 ? 35.237  -14.389 -5.801  1   35.177  ? 255  LEU A HD11 1 c 
ATOM   3765  H  HD12 . LEU A 1 249 ? 35.725  -12.982 -6.343  1   35.182  ? 255  LEU A HD12 1 c 
ATOM   3766  H  HD13 . LEU A 1 249 ? 36.54   -14.295 -6.701  1   35.182  ? 255  LEU A HD13 1 c 
ATOM   3767  H  HD21 . LEU A 1 249 ? 34.869  -13.488 -9.724  1   32.858  ? 255  LEU A HD21 1 c 
ATOM   3768  H  HD22 . LEU A 1 249 ? 36.288  -13.933 -9.17   1   32.837  ? 255  LEU A HD22 1 c 
ATOM   3769  H  HD23 . LEU A 1 249 ? 35.669  -12.537 -8.739  1   32.837  ? 255  LEU A HD23 1 c 
ATOM   3770  N  N    . GLU A 1 250 ? 32.658  -18.177 -8.572  1   36.369  ? 256  GLU A N    1 ? 
ATOM   3771  C  CA   . GLU A 1 250 ? 32.677  -19.621 -8.425  1   38.582  ? 256  GLU A CA   1 ? 
ATOM   3772  C  C    . GLU A 1 250 ? 31.939  -20.294 -9.585  1   36.806  ? 256  GLU A C    1 ? 
ATOM   3773  O  O    . GLU A 1 250 ? 30.73   -20.34  -9.588  1   33.964  ? 256  GLU A O    1 ? 
ATOM   3774  C  CB   . GLU A 1 250 ? 32.133  -20.056 -7.071  1   37.87   ? 256  GLU A CB   1 ? 
ATOM   3775  C  CG   . GLU A 1 250 ? 32.201  -21.57  -6.884  1   35.419  ? 256  GLU A CG   1 ? 
ATOM   3776  C  CD   . GLU A 1 250 ? 33.578  -22.191 -7.064  1   34.26   ? 256  GLU A CD   1 ? 
ATOM   3777  O  OE1  . GLU A 1 250 ? 33.842  -22.654 -8.182  1   32.517  ? 256  GLU A OE1  1 ? 
ATOM   3778  O  OE2  . GLU A 1 250 ? 34.397  -22.236 -6.111  1   36.273  ? 256  GLU A OE2  1 ? 
ATOM   3779  H  H    . GLU A 1 250 ? 31.968  -17.701 -8.209  1   37.726  ? 256  GLU A H    1 c 
ATOM   3780  H  HA   . GLU A 1 250 ? 33.623  -19.912 -8.459  1   37.684  ? 256  GLU A HA   1 c 
ATOM   3781  H  HB2  . GLU A 1 250 ? 32.651  -19.617 -6.364  1   37.445  ? 256  GLU A HB2  1 c 
ATOM   3782  H  HB3  . GLU A 1 250 ? 31.204  -19.759 -6.99   1   37.386  ? 256  GLU A HB3  1 c 
ATOM   3783  H  HG2  . GLU A 1 250 ? 31.882  -21.789 -5.982  1   35.685  ? 256  GLU A HG2  1 c 
ATOM   3784  H  HG3  . GLU A 1 250 ? 31.585  -21.996 -7.517  1   35.672  ? 256  GLU A HG3  1 c 
ATOM   3785  N  N    . ASN A 1 251 ? 32.678  -20.894 -10.529 1   39.29   ? 257  ASN A N    1 ? 
ATOM   3786  C  CA   . ASN A 1 251 ? 32.081  -21.452 -11.729 1   36.332  ? 257  ASN A CA   1 ? 
ATOM   3787  C  C    . ASN A 1 251 ? 31.965  -22.963 -11.69  1   42.199  ? 257  ASN A C    1 ? 
ATOM   3788  O  O    . ASN A 1 251 ? 31.635  -23.535 -12.727 1   40.868  ? 257  ASN A O    1 ? 
ATOM   3789  C  CB   . ASN A 1 251 ? 32.86   -21.123 -12.996 1   38.344  ? 257  ASN A CB   1 ? 
ATOM   3790  C  CG   . ASN A 1 251 ? 32.772  -19.648 -13.269 1   39.038  ? 257  ASN A CG   1 ? 
ATOM   3791  O  OD1  . ASN A 1 251 ? 31.662  -19.109 -13.348 1   42.905  ? 257  ASN A OD1  1 ? 
ATOM   3792  N  ND2  . ASN A 1 251 ? 33.909  -18.971 -13.288 1   36.535  ? 257  ASN A ND2  1 ? 
ATOM   3793  H  H    . ASN A 1 251 ? 33.583  -20.957 -10.419 1   38.007  ? 257  ASN A H    1 c 
ATOM   3794  H  HA   . ASN A 1 251 ? 31.178  -21.077 -11.832 1   38.294  ? 257  ASN A HA   1 c 
ATOM   3795  H  HB2  . ASN A 1 251 ? 33.796  -21.384 -12.884 1   38.029  ? 257  ASN A HB2  1 c 
ATOM   3796  H  HB3  . ASN A 1 251 ? 32.489  -21.615 -13.754 1   38.076  ? 257  ASN A HB3  1 c 
ATOM   3797  H  HD21 . ASN A 1 251 ? 33.903  -18.109 -13.5   1   37.331  ? 257  ASN A HD21 1 c 
ATOM   3798  H  HD22 . ASN A 1 251 ? 34.675  -19.372 -13.091 1   37.311  ? 257  ASN A HD22 1 c 
ATOM   3799  N  N    . ASP A 1 252 ? 32.208  -23.576 -10.521 1   40.755  ? 258  ASP A N    1 ? 
ATOM   3800  C  CA   . ASP A 1 252 ? 31.884  -24.971 -10.272 1   36.278  ? 258  ASP A CA   1 ? 
ATOM   3801  C  C    . ASP A 1 252 ? 30.555  -25.067 -9.529  1   36.006  ? 258  ASP A C    1 ? 
ATOM   3802  O  O    . ASP A 1 252 ? 30.4    -24.581 -8.41   1   36.368  ? 258  ASP A O    1 ? 
ATOM   3803  C  CB   . ASP A 1 252 ? 32.975  -25.669 -9.471  1   41.99   ? 258  ASP A CB   1 ? 
ATOM   3804  C  CG   . ASP A 1 252 ? 32.666  -27.127 -9.148  1   43.98   ? 258  ASP A CG   1 ? 
ATOM   3805  O  OD1  . ASP A 1 252 ? 31.971  -27.385 -8.128  1   34.877  ? 258  ASP A OD1  1 ? 
ATOM   3806  O  OD2  . ASP A 1 252 ? 33.061  -27.99  -9.97   1   47.307  ? 258  ASP A OD2  1 ? 
ATOM   3807  H  H    . ASP A 1 252 ? 32.602  -23.1   -9.847  1   39.974  ? 258  ASP A H    1 c 
ATOM   3808  H  HA   . ASP A 1 252 ? 31.802  -25.432 -11.136 1   38.132  ? 258  ASP A HA   1 c 
ATOM   3809  H  HB2  . ASP A 1 252 ? 33.814  -25.635 -9.977  1   41.037  ? 258  ASP A HB2  1 c 
ATOM   3810  H  HB3  . ASP A 1 252 ? 33.108  -25.188 -8.628  1   40.997  ? 258  ASP A HB3  1 c 
ATOM   3811  N  N    . ARG A 1 253 ? 29.58   -25.725 -10.138 1   37.583  ? 259  ARG A N    1 ? 
ATOM   3812  C  CA   . ARG A 1 253 ? 28.21   -25.607 -9.666  1   41.706  ? 259  ARG A CA   1 ? 
ATOM   3813  C  C    . ARG A 1 253 ? 28.118  -26.249 -8.277  1   40.098  ? 259  ARG A C    1 ? 
ATOM   3814  O  O    . ARG A 1 253 ? 27.523  -25.69  -7.365  1   36.912  ? 259  ARG A O    1 ? 
ATOM   3815  C  CB   . ARG A 1 253 ? 27.306  -26.132 -10.8   1   45.997  ? 259  ARG A CB   1 ? 
ATOM   3816  C  CG   . ARG A 1 253 ? 25.808  -26.164 -10.542 1   52.3    ? 259  ARG A CG   1 ? 
ATOM   3817  C  CD   . ARG A 1 253 ? 24.975  -26.596 -11.744 1   56.646  ? 259  ARG A CD   1 ? 
ATOM   3818  N  NE   . ARG A 1 253 ? 24.672  -28.031 -11.714 1   62.317  ? 259  ARG A NE   1 ? 
ATOM   3819  C  CZ   . ARG A 1 253 ? 23.483  -28.568 -11.936 1   57.367  ? 259  ARG A CZ   1 ? 
ATOM   3820  N  NH1  . ARG A 1 253 ? 23.343  -29.87  -11.908 1   61.564  ? 259  ARG A NH1  1 ? 
ATOM   3821  N  NH2  . ARG A 1 253 ? 22.432  -27.818 -12.205 1   61.716  ? 259  ARG A NH2  1 ? 
ATOM   3822  H  H    . ARG A 1 253 ? 29.764  -26.259 -10.857 1   38.178  ? 259  ARG A H    1 c 
ATOM   3823  H  HA   . ARG A 1 253 ? 28.009  -24.642 -9.563  1   41.255  ? 259  ARG A HA   1 c 
ATOM   3824  H  HB2  . ARG A 1 253 ? 27.468  -25.58  -11.594 1   46.421  ? 259  ARG A HB2  1 c 
ATOM   3825  H  HB3  . ARG A 1 253 ? 27.596  -27.044 -11.018 1   46.296  ? 259  ARG A HB3  1 c 
ATOM   3826  H  HG2  . ARG A 1 253 ? 25.63   -26.779 -9.799  1   51.757  ? 259  ARG A HG2  1 c 
ATOM   3827  H  HG3  . ARG A 1 253 ? 25.515  -25.27  -10.261 1   51.727  ? 259  ARG A HG3  1 c 
ATOM   3828  H  HD2  . ARG A 1 253 ? 24.14   -26.086 -11.75  1   56.926  ? 259  ARG A HD2  1 c 
ATOM   3829  H  HD3  . ARG A 1 253 ? 25.462  -26.387 -12.568 1   56.775  ? 259  ARG A HD3  1 c 
ATOM   3830  H  HE   . ARG A 1 253 ? 25.328  -28.574 -11.534 1   59.79   ? 259  ARG A HE   1 c 
ATOM   3831  H  HH11 . ARG A 1 253 ? 24.053  -30.393 -11.838 1   60.255  ? 259  ARG A HH11 1 c 
ATOM   3832  H  HH12 . ARG A 1 253 ? 22.533  -30.225 -11.959 1   60.255  ? 259  ARG A HH12 1 c 
ATOM   3833  H  HH21 . ARG A 1 253 ? 22.465  -27.233 -12.869 1   60.244  ? 259  ARG A HH21 1 c 
ATOM   3834  H  HH22 . ARG A 1 253 ? 21.696  -27.909 -11.722 1   60.127  ? 259  ARG A HH22 1 c 
ATOM   3835  N  N    . ASP A 1 254 ? 28.793  -27.39  -8.065  1   46.979  ? 260  ASP A N    1 ? 
ATOM   3836  C  CA   . ASP A 1 254 ? 28.73   -28.052 -6.763  1   45.913  ? 260  ASP A CA   1 ? 
ATOM   3837  C  C    . ASP A 1 254 ? 29.317  -27.144 -5.673  1   40.755  ? 260  ASP A C    1 ? 
ATOM   3838  O  O    . ASP A 1 254 ? 28.791  -27.023 -4.566  1   39.874  ? 260  ASP A O    1 ? 
ATOM   3839  C  CB   . ASP A 1 254 ? 29.334  -29.459 -6.816  1   45.692  ? 260  ASP A CB   1 ? 
ATOM   3840  C  CG   . ASP A 1 254 ? 28.672  -30.444 -7.778  1   46.111  ? 260  ASP A CG   1 ? 
ATOM   3841  O  OD1  . ASP A 1 254 ? 27.437  -30.445 -7.866  1   48.944  ? 260  ASP A OD1  1 ? 
ATOM   3842  O  OD2  . ASP A 1 254 ? 29.395  -31.22  -8.44   1   49.675  ? 260  ASP A OD2  1 ? 
ATOM   3843  H  H    . ASP A 1 254 ? 29.291  -27.764 -8.734  1   44.933  ? 260  ASP A H    1 c 
ATOM   3844  H  HA   . ASP A 1 254 ? 27.779  -28.188 -6.549  1   45.026  ? 260  ASP A HA   1 c 
ATOM   3845  H  HB2  . ASP A 1 254 ? 30.278  -29.381 -7.067  1   45.86   ? 260  ASP A HB2  1 c 
ATOM   3846  H  HB3  . ASP A 1 254 ? 29.296  -29.846 -5.917  1   45.842  ? 260  ASP A HB3  1 c 
ATOM   3847  N  N    . ARG A 1 255 ? 30.478  -26.557 -5.925  1   40.65   ? 261  ARG A N    1 ? 
ATOM   3848  C  CA   . ARG A 1 255 ? 31.059  -25.699 -4.903  1   41.3    ? 261  ARG A CA   1 ? 
ATOM   3849  C  C    . ARG A 1 255 ? 30.148  -24.489 -4.68   1   38.628  ? 261  ARG A C    1 ? 
ATOM   3850  O  O    . ARG A 1 255 ? 29.944  -24.104 -3.541  1   37.98   ? 261  ARG A O    1 ? 
ATOM   3851  C  CB   . ARG A 1 255 ? 32.509  -25.348 -5.244  1   43.363  ? 261  ARG A CB   1 ? 
ATOM   3852  C  CG   . ARG A 1 255 ? 33.498  -26.487 -5.027  1   39.916  ? 261  ARG A CG   1 ? 
ATOM   3853  C  CD   . ARG A 1 255 ? 34.915  -25.913 -4.996  1   39.999  ? 261  ARG A CD   1 ? 
ATOM   3854  N  NE   . ARG A 1 255 ? 35.204  -25.022 -6.134  1   44.947  ? 261  ARG A NE   1 ? 
ATOM   3855  C  CZ   . ARG A 1 255 ? 35.876  -25.33  -7.256  1   49.888  ? 261  ARG A CZ   1 ? 
ATOM   3856  N  NH1  . ARG A 1 255 ? 36.181  -24.361 -8.134  1   42.594  ? 261  ARG A NH1  1 ? 
ATOM   3857  N  NH2  . ARG A 1 255 ? 36.287  -26.59  -7.463  1   43.7    ? 261  ARG A NH2  1 ? 
ATOM   3858  H  H    . ARG A 1 255 ? 30.913  -26.684 -6.718  1   40.912  ? 261  ARG A H    1 c 
ATOM   3859  H  HA   . ARG A 1 255 ? 31.084  -26.215 -4.057  1   41.012  ? 261  ARG A HA   1 c 
ATOM   3860  H  HB2  . ARG A 1 255 ? 32.55   -25.068 -6.183  1   42.084  ? 261  ARG A HB2  1 c 
ATOM   3861  H  HB3  . ARG A 1 255 ? 32.783  -24.583 -4.694  1   42.053  ? 261  ARG A HB3  1 c 
ATOM   3862  H  HG2  . ARG A 1 255 ? 33.308  -26.938 -4.176  1   40.692  ? 261  ARG A HG2  1 c 
ATOM   3863  H  HG3  . ARG A 1 255 ? 33.424  -27.137 -5.76   1   40.691  ? 261  ARG A HG3  1 c 
ATOM   3864  H  HD2  . ARG A 1 255 ? 35.03   -25.411 -4.163  1   41.115  ? 261  ARG A HD2  1 c 
ATOM   3865  H  HD3  . ARG A 1 255 ? 35.56   -26.649 -4.988  1   41.198  ? 261  ARG A HD3  1 c 
ATOM   3866  H  HE   . ARG A 1 255 ? 34.919  -24.205 -6.07   1   44.737  ? 261  ARG A HE   1 c 
ATOM   3867  H  HH11 . ARG A 1 255 ? 36.106  -23.512 -7.9    1   44.723  ? 261  ARG A HH11 1 c 
ATOM   3868  H  HH12 . ARG A 1 255 ? 36.458  -24.578 -8.945  1   44.726  ? 261  ARG A HH12 1 c 
ATOM   3869  H  HH21 . ARG A 1 255 ? 35.875  -27.27  -7.071  1   45.43   ? 261  ARG A HH21 1 c 
ATOM   3870  H  HH22 . ARG A 1 255 ? 36.97   -26.734 -8.008  1   45.471  ? 261  ARG A HH22 1 c 
ATOM   3871  N  N    . LEU A 1 256 ? 29.519  -23.965 -5.742  1   39.392  ? 262  LEU A N    1 ? 
ATOM   3872  C  CA   . LEU A 1 256 ? 28.643  -22.794 -5.622  1   37.921  ? 262  LEU A CA   1 ? 
ATOM   3873  C  C    . LEU A 1 256 ? 27.433  -23.134 -4.752  1   39.501  ? 262  LEU A C    1 ? 
ATOM   3874  O  O    . LEU A 1 256 ? 27.144  -22.421 -3.794  1   41.44   ? 262  LEU A O    1 ? 
ATOM   3875  C  CB   . LEU A 1 256 ? 28.231  -22.262 -6.994  1   36.451  ? 262  LEU A CB   1 ? 
ATOM   3876  C  CG   . LEU A 1 256 ? 27.351  -21.008 -7.03   1   33.972  ? 262  LEU A CG   1 ? 
ATOM   3877  C  CD1  . LEU A 1 256 ? 28.079  -19.805 -6.44   1   33.637  ? 262  LEU A CD1  1 ? 
ATOM   3878  C  CD2  . LEU A 1 256 ? 26.94   -20.726 -8.446  1   34.391  ? 262  LEU A CD2  1 ? 
ATOM   3879  H  H    . LEU A 1 256 ? 29.641  -24.339 -6.567  1   38.887  ? 262  LEU A H    1 c 
ATOM   3880  H  HA   . LEU A 1 256 ? 29.158  -22.088 -5.154  1   38.182  ? 262  LEU A HA   1 c 
ATOM   3881  H  HB2  . LEU A 1 256 ? 29.052  -22.075 -7.506  1   36.194  ? 262  LEU A HB2  1 c 
ATOM   3882  H  HB3  . LEU A 1 256 ? 27.758  -22.983 -7.469  1   36.179  ? 262  LEU A HB3  1 c 
ATOM   3883  H  HG   . LEU A 1 256 ? 26.534  -21.178 -6.494  1   34.452  ? 262  LEU A HG   1 c 
ATOM   3884  H  HD11 . LEU A 1 256 ? 28.287  -19.977 -5.506  1   33.777  ? 262  LEU A HD11 1 c 
ATOM   3885  H  HD12 . LEU A 1 256 ? 27.512  -19.019 -6.504  1   33.694  ? 262  LEU A HD12 1 c 
ATOM   3886  H  HD13 . LEU A 1 256 ? 28.902  -19.65  -6.931  1   33.752  ? 262  LEU A HD13 1 c 
ATOM   3887  H  HD21 . LEU A 1 256 ? 26.441  -21.483 -8.797  1   34.336  ? 262  LEU A HD21 1 c 
ATOM   3888  H  HD22 . LEU A 1 256 ? 27.732  -20.582 -8.992  1   34.282  ? 262  LEU A HD22 1 c 
ATOM   3889  H  HD23 . LEU A 1 256 ? 26.382  -19.931 -8.471  1   34.282  ? 262  LEU A HD23 1 c 
ATOM   3890  N  N    . ALA A 1 257 ? 26.745  -24.247 -5.061  1   36.924  ? 263  ALA A N    1 ? 
ATOM   3891  C  CA   . ALA A 1 257 ? 25.565  -24.633 -4.3    1   36.501  ? 263  ALA A CA   1 ? 
ATOM   3892  C  C    . ALA A 1 257 ? 25.891  -24.843 -2.826  1   35.485  ? 263  ALA A C    1 ? 
ATOM   3893  O  O    . ALA A 1 257 ? 25.121  -24.479 -1.939  1   36.956  ? 263  ALA A O    1 ? 
ATOM   3894  C  CB   . ALA A 1 257 ? 24.958  -25.866 -4.904  1   34.696  ? 263  ALA A CB   1 ? 
ATOM   3895  H  H    . ALA A 1 257 ? 27.015  -24.77  -5.76   1   37.422  ? 263  ALA A H    1 c 
ATOM   3896  H  HA   . ALA A 1 257 ? 24.906  -23.889 -4.361  1   36.123  ? 263  ALA A HA   1 c 
ATOM   3897  H  HB1  . ALA A 1 257 ? 24.679  -25.68  -5.816  1   35.322  ? 263  ALA A HB1  1 c 
ATOM   3898  H  HB2  . ALA A 1 257 ? 25.612  -26.584 -4.909  1   35.315  ? 263  ALA A HB2  1 c 
ATOM   3899  H  HB3  . ALA A 1 257 ? 24.185  -26.14  -4.381  1   35.322  ? 263  ALA A HB3  1 c 
ATOM   3900  N  N    . LYS A 1 258 ? 27.039  -25.453 -2.56   1   35.336  ? 264  LYS A N    1 ? 
ATOM   3901  C  CA   . LYS A 1 258 ? 27.434  -25.662 -1.185  1   40.732  ? 264  LYS A CA   1 ? 
ATOM   3902  C  C    . LYS A 1 258 ? 27.586  -24.318 -0.458  1   38.872  ? 264  LYS A C    1 ? 
ATOM   3903  O  O    . LYS A 1 258 ? 27.139  -24.175 0.667   1   36.621  ? 264  LYS A O    1 ? 
ATOM   3904  C  CB   . LYS A 1 258 ? 28.662  -26.571 -1.205  1   43.975  ? 264  LYS A CB   1 ? 
ATOM   3905  C  CG   . LYS A 1 258 ? 29.022  -27.084 0.162   1   60.175  ? 264  LYS A CG   1 ? 
ATOM   3906  C  CD   . LYS A 1 258 ? 30.295  -27.919 0.227   1   69.788  ? 264  LYS A CD   1 ? 
ATOM   3907  C  CE   . LYS A 1 258 ? 30.682  -28.096 1.658   1   78.839  ? 264  LYS A CE   1 ? 
ATOM   3908  N  NZ   . LYS A 1 258 ? 31.826  -29     1.749   1   100.559 ? 264  LYS A NZ   1 ? 
ATOM   3909  H  H    . LYS A 1 258 ? 27.579  -25.746 -3.236  1   36.643  ? 264  LYS A H    1 c 
ATOM   3910  H  HA   . LYS A 1 258 ? 26.708  -26.166 -0.737  1   39.806  ? 264  LYS A HA   1 c 
ATOM   3911  H  HB2  . LYS A 1 258 ? 28.487  -27.337 -1.793  1   46.427  ? 264  LYS A HB2  1 c 
ATOM   3912  H  HB3  . LYS A 1 258 ? 29.426  -26.076 -1.57   1   46.484  ? 264  LYS A HB3  1 c 
ATOM   3913  H  HG2  . LYS A 1 258 ? 29.123  -26.314 0.763   1   57.835  ? 264  LYS A HG2  1 c 
ATOM   3914  H  HG3  . LYS A 1 258 ? 28.273  -27.624 0.498   1   57.842  ? 264  LYS A HG3  1 c 
ATOM   3915  H  HD2  . LYS A 1 258 ? 30.14   -28.798 -0.184  1   69.564  ? 264  LYS A HD2  1 c 
ATOM   3916  H  HD3  . LYS A 1 258 ? 31.018  -27.462 -0.256  1   69.457  ? 264  LYS A HD3  1 c 
ATOM   3917  H  HE2  . LYS A 1 258 ? 30.922  -27.235 2.046   1   81.043  ? 264  LYS A HE2  1 c 
ATOM   3918  H  HE3  . LYS A 1 258 ? 29.938  -28.469 2.163   1   81.212  ? 264  LYS A HE3  1 c 
ATOM   3919  H  HZ1  . LYS A 1 258 ? 32.51   -28.675 1.253   1   93.048  ? 264  LYS A HZ1  1 c 
ATOM   3920  H  HZ2  . LYS A 1 258 ? 31.595  -29.815 1.426   1   92.909  ? 264  LYS A HZ2  1 c 
ATOM   3921  H  HZ3  . LYS A 1 258 ? 32.08   -29.088 2.614   1   93.169  ? 264  LYS A HZ3  1 c 
ATOM   3922  N  N    . ALA A 1 259 ? 28.272  -23.35  -1.068  1   32.026  ? 265  ALA A N    1 ? 
ATOM   3923  C  CA   . ALA A 1 259 ? 28.461  -22.058 -0.44   1   33.744  ? 265  ALA A CA   1 ? 
ATOM   3924  C  C    . ALA A 1 259 ? 27.153  -21.255 -0.356  1   29.895  ? 265  ALA A C    1 ? 
ATOM   3925  O  O    . ALA A 1 259 ? 26.954  -20.584 0.647   1   31.458  ? 265  ALA A O    1 ? 
ATOM   3926  C  CB   . ALA A 1 259 ? 29.532  -21.272 -1.16   1   32.312  ? 265  ALA A CB   1 ? 
ATOM   3927  H  H    . ALA A 1 259 ? 28.633  -23.5   -1.894  1   33.977  ? 265  ALA A H    1 c 
ATOM   3928  H  HA   . ALA A 1 259 ? 28.771  -22.221 0.493   1   32.513  ? 265  ALA A HA   1 c 
ATOM   3929  H  HB1  . ALA A 1 259 ? 30.373  -21.758 -1.126  1   32.732  ? 265  ALA A HB1  1 c 
ATOM   3930  H  HB2  . ALA A 1 259 ? 29.274  -21.142 -2.088  1   32.732  ? 265  ALA A HB2  1 c 
ATOM   3931  H  HB3  . ALA A 1 259 ? 29.644  -20.406 -0.734  1   32.737  ? 265  ALA A HB3  1 c 
ATOM   3932  N  N    . VAL A 1 260 ? 26.284  -21.301 -1.378  1   32.441  ? 266  VAL A N    1 ? 
ATOM   3933  C  CA   . VAL A 1 260 ? 25.069  -20.483 -1.346  1   34.751  ? 266  VAL A CA   1 ? 
ATOM   3934  C  C    . VAL A 1 260 ? 24.127  -21.075 -0.29   1   38.294  ? 266  VAL A C    1 ? 
ATOM   3935  O  O    . VAL A 1 260 ? 23.555  -20.342 0.537   1   36.821  ? 266  VAL A O    1 ? 
ATOM   3936  C  CB   . VAL A 1 260 ? 24.437  -20.287 -2.735  1   34.571  ? 266  VAL A CB   1 ? 
ATOM   3937  C  CG1  . VAL A 1 260 ? 23.124  -19.493 -2.74   1   38.938  ? 266  VAL A CG1  1 ? 
ATOM   3938  C  CG2  . VAL A 1 260 ? 25.407  -19.627 -3.689  1   34.843  ? 266  VAL A CG2  1 ? 
ATOM   3939  H  H    . VAL A 1 260 ? 26.445  -21.839 -2.1    1   32.32   ? 266  VAL A H    1 c 
ATOM   3940  H  HA   . VAL A 1 260 ? 25.332  -19.596 -1.03   1   34.831  ? 266  VAL A HA   1 c 
ATOM   3941  H  HB   . VAL A 1 260 ? 24.239  -21.186 -3.09   1   35.428  ? 266  VAL A HB   1 c 
ATOM   3942  H  HG11 . VAL A 1 260 ? 23.267  -18.627 -2.323  1   37.596  ? 266  VAL A HG11 1 c 
ATOM   3943  H  HG12 . VAL A 1 260 ? 22.445  -19.982 -2.246  1   37.599  ? 266  VAL A HG12 1 c 
ATOM   3944  H  HG13 . VAL A 1 260 ? 22.825  -19.365 -3.656  1   37.568  ? 266  VAL A HG13 1 c 
ATOM   3945  H  HG21 . VAL A 1 260 ? 24.98   -19.502 -4.553  1   34.802  ? 266  VAL A HG21 1 c 
ATOM   3946  H  HG22 . VAL A 1 260 ? 26.192  -20.188 -3.797  1   34.778  ? 266  VAL A HG22 1 c 
ATOM   3947  H  HG23 . VAL A 1 260 ? 25.675  -18.764 -3.333  1   34.758  ? 266  VAL A HG23 1 c 
ATOM   3948  N  N    . TRP A 1 261 ? 24.09   -22.411 -0.214  1   37.687  ? 267  TRP A N    1 ? 
ATOM   3949  C  CA   . TRP A 1 261 ? 23.321  -23.076 0.831   1   38.596  ? 267  TRP A CA   1 ? 
ATOM   3950  C  C    . TRP A 1 261 ? 23.775  -22.669 2.237   1   41.113  ? 267  TRP A C    1 ? 
ATOM   3951  O  O    . TRP A 1 261 ? 22.95   -22.395 3.117   1   41.982  ? 267  TRP A O    1 ? 
ATOM   3952  C  CB   . TRP A 1 261 ? 23.379  -24.597 0.64    1   39.57   ? 267  TRP A CB   1 ? 
ATOM   3953  C  CG   . TRP A 1 261 ? 22.457  -25.324 1.59    1   38.839  ? 267  TRP A CG   1 ? 
ATOM   3954  C  CD1  . TRP A 1 261 ? 22.839  -26.033 2.678   1   40.029  ? 267  TRP A CD1  1 ? 
ATOM   3955  C  CD2  . TRP A 1 261 ? 21.01   -25.365 1.575   1   38.06   ? 267  TRP A CD2  1 ? 
ATOM   3956  N  NE1  . TRP A 1 261 ? 21.746  -26.569 3.309   1   48.126  ? 267  TRP A NE1  1 ? 
ATOM   3957  C  CE2  . TRP A 1 261 ? 20.609  -26.159 2.672   1   41.795  ? 267  TRP A CE2  1 ? 
ATOM   3958  C  CE3  . TRP A 1 261 ? 20.016  -24.81  0.756   1   38.917  ? 267  TRP A CE3  1 ? 
ATOM   3959  C  CZ2  . TRP A 1 261 ? 19.272  -26.43  2.953   1   40.853  ? 267  TRP A CZ2  1 ? 
ATOM   3960  C  CZ3  . TRP A 1 261 ? 18.694  -25.055 1.05    1   40.76   ? 267  TRP A CZ3  1 ? 
ATOM   3961  C  CH2  . TRP A 1 261 ? 18.331  -25.891 2.105   1   37.883  ? 267  TRP A CH2  1 ? 
ATOM   3962  H  H    . TRP A 1 261 ? 24.542  -22.919 -0.826  1   37.977  ? 267  TRP A H    1 c 
ATOM   3963  H  HA   . TRP A 1 261 ? 22.372  -22.797 0.726   1   39.041  ? 267  TRP A HA   1 c 
ATOM   3964  H  HB2  . TRP A 1 261 ? 23.121  -24.809 -0.282  1   39.167  ? 267  TRP A HB2  1 c 
ATOM   3965  H  HB3  . TRP A 1 261 ? 24.3    -24.899 0.791   1   39.177  ? 267  TRP A HB3  1 c 
ATOM   3966  H  HD1  . TRP A 1 261 ? 23.734  -26.2   2.93    1   41.451  ? 267  TRP A HD1  1 c 
ATOM   3967  H  HE1  . TRP A 1 261 ? 21.773  -27.068 4.025   1   44.46   ? 267  TRP A HE1  1 c 
ATOM   3968  H  HE3  . TRP A 1 261 ? 20.251  -24.271 0.022   1   39.173  ? 267  TRP A HE3  1 c 
ATOM   3969  H  HZ2  . TRP A 1 261 ? 19.025  -26.97  3.684   1   40.365  ? 267  TRP A HZ2  1 c 
ATOM   3970  H  HZ3  . TRP A 1 261 ? 18.023  -24.705 0.488   1   39.678  ? 267  TRP A HZ3  1 c 
ATOM   3971  H  HH2  . TRP A 1 261 ? 17.418  -26.031 2.287   1   39.253  ? 267  TRP A HH2  1 c 
ATOM   3972  N  N    . ARG A 1 262 ? 25.086  -22.651 2.491   1   36.503  ? 268  ARG A N    1 ? 
ATOM   3973  C  CA   . ARG A 1 262 ? 25.551  -22.226 3.807   1   43.986  ? 268  ARG A CA   1 ? 
ATOM   3974  C  C    . ARG A 1 262 ? 25.111  -20.781 4.144   1   38.877  ? 268  ARG A C    1 ? 
ATOM   3975  O  O    . ARG A 1 262 ? 24.552  -20.509 5.208   1   39.272  ? 268  ARG A O    1 ? 
ATOM   3976  C  CB   . ARG A 1 262 ? 27.052  -22.519 3.862   1   40.594  ? 268  ARG A CB   1 ? 
ATOM   3977  C  CG   . ARG A 1 262 ? 27.768  -21.807 4.994   1   41.692  ? 268  ARG A CG   1 ? 
ATOM   3978  C  CD   . ARG A 1 262 ? 29.225  -22.183 4.857   1   54.761  ? 268  ARG A CD   1 ? 
ATOM   3979  N  NE   . ARG A 1 262 ? 30.012  -21.895 6.059   1   61.048  ? 268  ARG A NE   1 ? 
ATOM   3980  C  CZ   . ARG A 1 262 ? 30.614  -22.814 6.781   1   58.537  ? 268  ARG A CZ   1 ? 
ATOM   3981  N  NH1  . ARG A 1 262 ? 30.344  -24.082 6.568   1   56.64   ? 268  ARG A NH1  1 ? 
ATOM   3982  N  NH2  . ARG A 1 262 ? 31.445  -22.454 7.737   1   69.253  ? 268  ARG A NH2  1 ? 
ATOM   3983  H  H    . ARG A 1 262 ? 25.69   -22.905 1.853   1   39.168  ? 268  ARG A H    1 c 
ATOM   3984  H  HA   . ARG A 1 262 ? 25.129  -22.821 4.475   1   40.917  ? 268  ARG A HA   1 c 
ATOM   3985  H  HB2  . ARG A 1 262 ? 27.18   -23.486 3.963   1   41.731  ? 268  ARG A HB2  1 c 
ATOM   3986  H  HB3  . ARG A 1 262 ? 27.46   -22.249 3.012   1   41.632  ? 268  ARG A HB3  1 c 
ATOM   3987  H  HG2  . ARG A 1 262 ? 27.666  -20.834 4.909   1   44.089  ? 268  ARG A HG2  1 c 
ATOM   3988  H  HG3  . ARG A 1 262 ? 27.423  -22.11  5.862   1   44.109  ? 268  ARG A HG3  1 c 
ATOM   3989  H  HD2  . ARG A 1 262 ? 29.298  -23.135 4.641   1   52.706  ? 268  ARG A HD2  1 c 
ATOM   3990  H  HD3  . ARG A 1 262 ? 29.599  -21.679 4.107   1   52.739  ? 268  ARG A HD3  1 c 
ATOM   3991  H  HE   . ARG A 1 262 ? 30.084  -21.063 6.309   1   59.069  ? 268  ARG A HE   1 c 
ATOM   3992  H  HH11 . ARG A 1 262 ? 29.517  -24.379 6.673   1   57.165  ? 268  ARG A HH11 1 c 
ATOM   3993  H  HH12 . ARG A 1 262 ? 30.992  -24.633 6.321   1   57.205  ? 268  ARG A HH12 1 c 
ATOM   3994  H  HH21 . ARG A 1 262 ? 31.539  -21.599 7.944   1   65.626  ? 268  ARG A HH21 1 c 
ATOM   3995  H  HH22 . ARG A 1 262 ? 31.906  -23.07  8.171   1   65.593  ? 268  ARG A HH22 1 c 
ATOM   3996  N  N    . SER A 1 263 ? 25.27   -19.855 3.198   1   35.399  ? 269  SER A N    1 ? 
ATOM   3997  C  CA   . SER A 1 263 ? 24.813  -18.473 3.377   1   35.526  ? 269  SER A CA   1 ? 
ATOM   3998  C  C    . SER A 1 263 ? 23.317  -18.39  3.686   1   36.134  ? 269  SER A C    1 ? 
ATOM   3999  O  O    . SER A 1 263 ? 22.905  -17.565 4.506   1   33.868  ? 269  SER A O    1 ? 
ATOM   4000  C  CB   . SER A 1 263 ? 25.17   -17.616 2.153   1   37.841  ? 269  SER A CB   1 ? 
ATOM   4001  O  OG   . SER A 1 263 ? 24.267  -17.842 1.078   1   36.263  ? 269  SER A OG   1 ? 
ATOM   4002  H  H    . SER A 1 263 ? 25.677  -20.084 2.413   1   36.294  ? 269  SER A H    1 c 
ATOM   4003  H  HA   . SER A 1 263 ? 25.294  -18.1   4.156   1   36.073  ? 269  SER A HA   1 c 
ATOM   4004  H  HB2  . SER A 1 263 ? 25.145  -16.673 2.403   1   36.934  ? 269  SER A HB2  1 c 
ATOM   4005  H  HB3  . SER A 1 263 ? 26.077  -17.829 1.864   1   36.93   ? 269  SER A HB3  1 c 
ATOM   4006  H  HG   . SER A 1 263 ? 24.484  -17.338 0.45    0   36.51   ? 269  SER A HG   1 c 
ATOM   4007  N  N    . MET A 1 264 ? 22.503  -19.247 3.047   1   35.587  ? 270  MET A N    1 ? 
ATOM   4008  C  CA   . MET A 1 264 ? 21.077  -19.317 3.377   1   35.071  ? 270  MET A CA   1 ? 
ATOM   4009  C  C    . MET A 1 264 ? 20.852  -19.821 4.812   1   38.135  ? 270  MET A C    1 ? 
ATOM   4010  O  O    . MET A 1 264 ? 20.06   -19.225 5.545   1   31.977  ? 270  MET A O    1 ? 
ATOM   4011  C  CB   . MET A 1 264 ? 20.288  -20.173 2.377   1   36.196  ? 270  MET A CB   1 ? 
ATOM   4012  C  CG   . MET A 1 264 ? 20.381  -19.664 0.955   1   35.81   ? 270  MET A CG   1 ? 
ATOM   4013  S  SD   . MET A 1 264 ? 19.86   -20.811 -0.347  1   38.049  ? 270  MET A SD   1 ? 
ATOM   4014  C  CE   . MET A 1 264 ? 18.349  -21.355 0.459   1   38.76   ? 270  MET A CE   1 ? 
ATOM   4015  H  H    . MET A 1 264 ? 22.838  -19.799 2.4     1   35.61   ? 270  MET A H    1 c 
ATOM   4016  H  HA   . MET A 1 264 ? 20.723  -18.392 3.336   1   35.875  ? 270  MET A HA   1 c 
ATOM   4017  H  HB2  . MET A 1 264 ? 20.628  -21.093 2.412   1   35.859  ? 270  MET A HB2  1 c 
ATOM   4018  H  HB3  . MET A 1 264 ? 19.347  -20.188 2.652   1   35.894  ? 270  MET A HB3  1 c 
ATOM   4019  H  HG2  . MET A 1 264 ? 19.834  -18.857 0.88    1   36.317  ? 270  MET A HG2  1 c 
ATOM   4020  H  HG3  . MET A 1 264 ? 21.303  -19.403 0.775   1   36.313  ? 270  MET A HG3  1 c 
ATOM   4021  H  HE1  . MET A 1 264 ? 17.822  -21.883 -0.167  1   38.647  ? 270  MET A HE1  1 c 
ATOM   4022  H  HE2  . MET A 1 264 ? 18.571  -21.903 1.234   1   38.564  ? 270  MET A HE2  1 c 
ATOM   4023  H  HE3  . MET A 1 264 ? 17.834  -20.577 0.744   1   38.585  ? 270  MET A HE3  1 c 
ATOM   4024  N  N    . GLN A 1 265 ? 21.604  -20.841 5.26    1   32.437  ? 271  GLN A N    1 ? 
ATOM   4025  C  CA   . GLN A 1 265 ? 21.437  -21.341 6.621   1   35.689  ? 271  GLN A CA   1 ? 
ATOM   4026  C  C    . GLN A 1 265 ? 21.874  -20.265 7.616   1   37.925  ? 271  GLN A C    1 ? 
ATOM   4027  O  O    . GLN A 1 265 ? 21.32   -20.182 8.708   1   36.037  ? 271  GLN A O    1 ? 
ATOM   4028  C  CB   . GLN A 1 265 ? 22.234  -22.603 6.968   1   36.807  ? 271  GLN A CB   1 ? 
ATOM   4029  C  CG   . GLN A 1 265 ? 21.927  -23.835 6.126   1   37.382  ? 271  GLN A CG   1 ? 
ATOM   4030  C  CD   . GLN A 1 265 ? 23.044  -24.857 6.199   1   44.849  ? 271  GLN A CD   1 ? 
ATOM   4031  O  OE1  . GLN A 1 265 ? 24.199  -24.632 5.821   1   50.057  ? 271  GLN A OE1  1 ? 
ATOM   4032  N  NE2  . GLN A 1 265 ? 22.727  -26.006 6.739   1   49.299  ? 271  GLN A NE2  1 ? 
ATOM   4033  H  H    . GLN A 1 265 ? 22.223  -21.232 4.712   1   34.456  ? 271  GLN A H    1 c 
ATOM   4034  H  HA   . GLN A 1 265 ? 20.475  -21.53  6.765   1   35.614  ? 271  GLN A HA   1 c 
ATOM   4035  H  HB2  . GLN A 1 265 ? 23.188  -22.395 6.88    1   36.788  ? 271  GLN A HB2  1 c 
ATOM   4036  H  HB3  . GLN A 1 265 ? 22.07   -22.821 7.909   1   36.707  ? 271  GLN A HB3  1 c 
ATOM   4037  H  HG2  . GLN A 1 265 ? 21.094  -24.242 6.439   1   39.062  ? 271  GLN A HG2  1 c 
ATOM   4038  H  HG3  . GLN A 1 265 ? 21.798  -23.567 5.192   1   38.866  ? 271  GLN A HG3  1 c 
ATOM   4039  H  HE21 . GLN A 1 265 ? 23.313  -26.673 6.731   1   47.859  ? 271  GLN A HE21 1 c 
ATOM   4040  H  HE22 . GLN A 1 265 ? 21.931  -26.124 7.114   1   47.708  ? 271  GLN A HE22 1 c 
ATOM   4041  N  N    . SER A 1 266 ? 22.889  -19.455 7.253   1   32.483  ? 272  SER A N    1 ? 
ATOM   4042  C  CA   . SER A 1 266 ? 23.389  -18.454 8.183   1   32.4    ? 272  SER A CA   1 ? 
ATOM   4043  C  C    . SER A 1 266 ? 22.38   -17.328 8.299   1   33.287  ? 272  SER A C    1 ? 
ATOM   4044  O  O    . SER A 1 266 ? 22.104  -16.835 9.392   1   36.906  ? 272  SER A O    1 ? 
ATOM   4045  C  CB   . SER A 1 266 ? 24.764  -17.891 7.779   1   34.592  ? 272  SER A CB   1 ? 
ATOM   4046  O  OG   . SER A 1 266 ? 25.258  -16.965 8.747   1   34.396  ? 272  SER A OG   1 ? 
ATOM   4047  H  H    . SER A 1 266 ? 23.274  -19.534 6.428   1   33.719  ? 272  SER A H    1 c 
ATOM   4048  H  HA   . SER A 1 266 ? 23.479  -18.88  9.074   1   33.008  ? 272  SER A HA   1 c 
ATOM   4049  H  HB2  . SER A 1 266 ? 25.397  -18.628 7.683   1   34.104  ? 272  SER A HB2  1 c 
ATOM   4050  H  HB3  . SER A 1 266 ? 24.686  -17.445 6.914   1   34.058  ? 272  SER A HB3  1 c 
ATOM   4051  H  HG   . SER A 1 266 ? 26.025  -16.69  8.478   0   33.83   ? 272  SER A HG   1 c 
ATOM   4052  N  N    . VAL A 1 267 ? 21.883  -16.868 7.159   1   33.378  ? 273  VAL A N    1 ? 
ATOM   4053  C  CA   . VAL A 1 267 ? 20.986  -15.714 7.155   1   35.715  ? 273  VAL A CA   1 ? 
ATOM   4054  C  C    . VAL A 1 267 ? 19.659  -16.107 7.811   1   37.176  ? 273  VAL A C    1 ? 
ATOM   4055  O  O    . VAL A 1 267 ? 18.991  -15.281 8.455   1   36.373  ? 273  VAL A O    1 ? 
ATOM   4056  C  CB   . VAL A 1 267 ? 20.786  -15.161 5.728   1   36.801  ? 273  VAL A CB   1 ? 
ATOM   4057  C  CG1  . VAL A 1 267 ? 19.532  -14.3   5.591   1   38.167  ? 273  VAL A CG1  1 ? 
ATOM   4058  C  CG2  . VAL A 1 267 ? 22      -14.368 5.251   1   37.157  ? 273  VAL A CG2  1 ? 
ATOM   4059  H  H    . VAL A 1 267 ? 22.105  -17.265 6.366   1   33.887  ? 273  VAL A H    1 c 
ATOM   4060  H  HA   . VAL A 1 267 ? 21.396  -15.012 7.696   1   35.693  ? 273  VAL A HA   1 c 
ATOM   4061  H  HB   . VAL A 1 267 ? 20.681  -15.937 5.128   1   36.892  ? 273  VAL A HB   1 c 
ATOM   4062  H  HG11 . VAL A 1 267 ? 19.51   -13.641 6.306   1   37.751  ? 273  VAL A HG11 1 c 
ATOM   4063  H  HG12 . VAL A 1 267 ? 18.741  -14.862 5.645   1   37.738  ? 273  VAL A HG12 1 c 
ATOM   4064  H  HG13 . VAL A 1 267 ? 19.543  -13.844 4.733   1   37.747  ? 273  VAL A HG13 1 c 
ATOM   4065  H  HG21 . VAL A 1 267 ? 21.847  -14.053 4.344   1   37.057  ? 273  VAL A HG21 1 c 
ATOM   4066  H  HG22 . VAL A 1 267 ? 22.787  -14.938 5.266   1   37.053  ? 273  VAL A HG22 1 c 
ATOM   4067  H  HG23 . VAL A 1 267 ? 22.141  -13.606 5.837   1   37.053  ? 273  VAL A HG23 1 c 
ATOM   4068  N  N    . ASP A 1 268 ? 19.26   -17.38  7.654   1   36.357  ? 274  ASP A N    1 ? 
ATOM   4069  C  CA   . ASP A 1 268 ? 18.043  -17.849 8.311   1   38.292  ? 274  ASP A CA   1 ? 
ATOM   4070  C  C    . ASP A 1 268 ? 18.128  -17.669 9.825   1   35.14   ? 274  ASP A C    1 ? 
ATOM   4071  O  O    . ASP A 1 268 ? 17.118  -17.407 10.473  1   39.717  ? 274  ASP A O    1 ? 
ATOM   4072  C  CB   . ASP A 1 268 ? 17.68   -19.278 7.959   1   36.913  ? 274  ASP A CB   1 ? 
ATOM   4073  C  CG   . ASP A 1 268 ? 16.741  -19.432 6.78    1   37.497  ? 274  ASP A CG   1 ? 
ATOM   4074  O  OD1  . ASP A 1 268 ? 16.017  -18.432 6.456   1   37.089  ? 274  ASP A OD1  1 ? 
ATOM   4075  O  OD2  . ASP A 1 268 ? 16.788  -20.532 6.18    1   36.44   ? 274  ASP A OD2  1 ? 
ATOM   4076  H  H    . ASP A 1 268 ? 19.737  -17.955 7.128   1   36.944  ? 274  ASP A H    1 c 
ATOM   4077  H  HA   . ASP A 1 268 ? 17.303  -17.287 7.993   1   37.058  ? 274  ASP A HA   1 c 
ATOM   4078  H  HB2  . ASP A 1 268 ? 18.502  -19.774 7.76    1   37.347  ? 274  ASP A HB2  1 c 
ATOM   4079  H  HB3  . ASP A 1 268 ? 17.257  -19.701 8.735   1   37.342  ? 274  ASP A HB3  1 c 
ATOM   4080  N  N    . LYS A 1 269 ? 19.329  -17.813 10.374  1   37.969  ? 275  LYS A N    1 ? 
ATOM   4081  C  CA   . LYS A 1 269 ? 19.574  -17.522 11.778  1   34.654  ? 275  LYS A CA   1 ? 
ATOM   4082  C  C    . LYS A 1 269 ? 19.16   -16.103 12.113  1   36.289  ? 275  LYS A C    1 ? 
ATOM   4083  O  O    . LYS A 1 269 ? 18.551  -15.875 13.145  1   41.269  ? 275  LYS A O    1 ? 
ATOM   4084  C  CB   . LYS A 1 269 ? 21.049  -17.633 12.177  1   36.71   ? 275  LYS A CB   1 ? 
ATOM   4085  C  CG   . LYS A 1 269 ? 21.734  -18.959 11.917  1   34.811  ? 275  LYS A CG   1 ? 
ATOM   4086  C  CD   . LYS A 1 269 ? 21.062  -20.153 12.567  1   38.445  ? 275  LYS A CD   1 ? 
ATOM   4087  C  CE   . LYS A 1 269 ? 21.548  -21.441 12.01   1   46.274  ? 275  LYS A CE   1 ? 
ATOM   4088  N  NZ   . LYS A 1 269 ? 20.981  -22.563 12.775  1   50.869  ? 275  LYS A NZ   1 ? 
ATOM   4089  H  H    . LYS A 1 269 ? 20.024  -18.11  9.86    1   36.501  ? 275  LYS A H    1 c 
ATOM   4090  H  HA   . LYS A 1 269 ? 19.035  -18.147 12.327  1   36.012  ? 275  LYS A HA   1 c 
ATOM   4091  H  HB2  . LYS A 1 269 ? 21.549  -16.934 11.706  1   35.802  ? 275  LYS A HB2  1 c 
ATOM   4092  H  HB3  . LYS A 1 269 ? 21.118  -17.443 13.137  1   35.795  ? 275  LYS A HB3  1 c 
ATOM   4093  H  HG2  . LYS A 1 269 ? 21.773  -19.104 10.948  1   36.109  ? 275  LYS A HG2  1 c 
ATOM   4094  H  HG3  . LYS A 1 269 ? 22.658  -18.899 12.244  1   36.111  ? 275  LYS A HG3  1 c 
ATOM   4095  H  HD2  . LYS A 1 269 ? 21.238  -20.134 13.533  1   39.301  ? 275  LYS A HD2  1 c 
ATOM   4096  H  HD3  . LYS A 1 269 ? 20.092  -20.094 12.433  1   39.22   ? 275  LYS A HD3  1 c 
ATOM   4097  H  HE2  . LYS A 1 269 ? 21.281  -21.521 11.077  1   45.333  ? 275  LYS A HE2  1 c 
ATOM   4098  H  HE3  . LYS A 1 269 ? 22.52   -21.478 12.058  1   45.333  ? 275  LYS A HE3  1 c 
ATOM   4099  H  HZ1  . LYS A 1 269 ? 20.076  -22.534 12.738  1   49.302  ? 275  LYS A HZ1  1 c 
ATOM   4100  H  HZ2  . LYS A 1 269 ? 21.245  -22.51  13.64   1   49.245  ? 275  LYS A HZ2  1 c 
ATOM   4101  H  HZ3  . LYS A 1 269 ? 21.267  -23.348 12.425  1   49.357  ? 275  LYS A HZ3  1 c 
ATOM   4102  N  N    . PHE A 1 270 ? 19.503  -15.145 11.245  1   34.279  ? 276  PHE A N    1 ? 
ATOM   4103  C  CA   . PHE A 1 270 ? 19.149  -13.754 11.487  1   36.445  ? 276  PHE A CA   1 ? 
ATOM   4104  C  C    . PHE A 1 270 ? 17.63   -13.571 11.334  1   38.129  ? 276  PHE A C    1 ? 
ATOM   4105  O  O    . PHE A 1 270 ? 16.972  -12.91  12.129  1   37.022  ? 276  PHE A O    1 ? 
ATOM   4106  C  CB   . PHE A 1 270 ? 19.96   -12.813 10.569  1   35.264  ? 276  PHE A CB   1 ? 
ATOM   4107  C  CG   . PHE A 1 270 ? 19.459  -11.368 10.547  1   34.443  ? 276  PHE A CG   1 ? 
ATOM   4108  C  CD1  . PHE A 1 270 ? 19.871  -10.452 11.505  1   31.855  ? 276  PHE A CD1  1 ? 
ATOM   4109  C  CD2  . PHE A 1 270 ? 18.562  -10.938 9.595   1   33.816  ? 276  PHE A CD2  1 ? 
ATOM   4110  C  CE1  . PHE A 1 270 ? 19.433  -9.151  11.496  1   29.226  ? 276  PHE A CE1  1 ? 
ATOM   4111  C  CE2  . PHE A 1 270 ? 18.109  -9.622  9.593   1   39.998  ? 276  PHE A CE2  1 ? 
ATOM   4112  C  CZ   . PHE A 1 270 ? 18.558  -8.733  10.542  1   34.405  ? 276  PHE A CZ   1 ? 
ATOM   4113  H  H    . PHE A 1 270 ? 19.977  -15.358 10.494  1   35.255  ? 276  PHE A H    1 c 
ATOM   4114  H  HA   . PHE A 1 270 ? 19.389  -13.539 12.428  1   36.119  ? 276  PHE A HA   1 c 
ATOM   4115  H  HB2  . PHE A 1 270 ? 20.897  -12.819 10.868  1   35.359  ? 276  PHE A HB2  1 c 
ATOM   4116  H  HB3  . PHE A 1 270 ? 19.935  -13.171 9.655   1   35.346  ? 276  PHE A HB3  1 c 
ATOM   4117  H  HD1  . PHE A 1 270 ? 20.487  -10.726 12.165  1   31.957  ? 276  PHE A HD1  1 c 
ATOM   4118  H  HD2  . PHE A 1 270 ? 18.258  -11.539 8.935   1   35.256  ? 276  PHE A HD2  1 c 
ATOM   4119  H  HE1  . PHE A 1 270 ? 19.737  -8.547  12.155  1   31.1    ? 276  PHE A HE1  1 c 
ATOM   4120  H  HE2  . PHE A 1 270 ? 17.503  -9.335  8.929   1   37.012  ? 276  PHE A HE2  1 c 
ATOM   4121  H  HZ   . PHE A 1 270 ? 18.246  -7.842  10.542  1   34.268  ? 276  PHE A HZ   1 c 
ATOM   4122  N  N    . ILE A 1 271 ? 17.052  -14.168 10.304  1   38.458  ? 277  ILE A N    1 ? 
ATOM   4123  C  CA   . ILE A 1 271 ? 15.627  -14.001 10.071  1   39.733  ? 277  ILE A CA   1 ? 
ATOM   4124  C  C    . ILE A 1 271 ? 14.827  -14.678 11.2    1   45.849  ? 277  ILE A C    1 ? 
ATOM   4125  O  O    . ILE A 1 271 ? 13.736  -14.215 11.536  1   37.452  ? 277  ILE A O    1 ? 
ATOM   4126  C  CB   . ILE A 1 271 ? 15.28   -14.514 8.664   1   34.873  ? 277  ILE A CB   1 ? 
ATOM   4127  C  CG1  . ILE A 1 271 ? 16.057  -13.699 7.557   1   35.922  ? 277  ILE A CG1  1 ? 
ATOM   4128  C  CG2  . ILE A 1 271 ? 13.776  -14.496 8.441   1   37.098  ? 277  ILE A CG2  1 ? 
ATOM   4129  C  CD1  . ILE A 1 271 ? 15.852  -14.195 6.132   1   30.626  ? 277  ILE A CD1  1 ? 
ATOM   4130  H  H    . ILE A 1 271 ? 17.543  -14.691 9.738   1   38.52   ? 277  ILE A H    1 c 
ATOM   4131  H  HA   . ILE A 1 271 ? 15.43   -13.044 10.094  1   39.548  ? 277  ILE A HA   1 c 
ATOM   4132  H  HB   . ILE A 1 271 ? 15.577  -15.444 8.608   1   36.361  ? 277  ILE A HB   1 c 
ATOM   4133  H  HG12 . ILE A 1 271 ? 15.772  -12.764 7.604   1   34.407  ? 277  ILE A HG12 1 c 
ATOM   4134  H  HG13 . ILE A 1 271 ? 17.013  -13.727 7.76    1   34.454  ? 277  ILE A HG13 1 c 
ATOM   4135  H  HG21 . ILE A 1 271 ? 13.577  -14.757 7.527   1   36.373  ? 277  ILE A HG21 1 c 
ATOM   4136  H  HG22 . ILE A 1 271 ? 13.434  -13.6   8.601   1   36.424  ? 277  ILE A HG22 1 c 
ATOM   4137  H  HG23 . ILE A 1 271 ? 13.346  -15.118 9.051   1   36.464  ? 277  ILE A HG23 1 c 
ATOM   4138  H  HD11 . ILE A 1 271 ? 16.034  -15.154 6.091   1   32.112  ? 277  ILE A HD11 1 c 
ATOM   4139  H  HD12 . ILE A 1 271 ? 16.463  -13.725 5.533   1   32.112  ? 277  ILE A HD12 1 c 
ATOM   4140  H  HD13 . ILE A 1 271 ? 14.933  -14.027 5.852   1   32.149  ? 277  ILE A HD13 1 c 
ATOM   4141  N  N    . ASN A 1 272 ? 15.404  -15.734 11.805  1   40.735  ? 278  ASN A N    1 ? 
ATOM   4142  C  CA   . ASN A 1 272 ? 14.785  -16.474 12.892  1   42.16   ? 278  ASN A CA   1 ? 
ATOM   4143  C  C    . ASN A 1 272 ? 14.788  -15.67  14.187  1   44.678  ? 278  ASN A C    1 ? 
ATOM   4144  O  O    . ASN A 1 272 ? 13.925  -15.895 15.036  1   42.645  ? 278  ASN A O    1 ? 
ATOM   4145  C  CB   . ASN A 1 272 ? 15.53   -17.775 13.189  1   39.36   ? 278  ASN A CB   1 ? 
ATOM   4146  C  CG   . ASN A 1 272 ? 15.286  -18.841 12.157  1   36.899  ? 278  ASN A CG   1 ? 
ATOM   4147  O  OD1  . ASN A 1 272 ? 14.438  -18.68  11.286  1   40.961  ? 278  ASN A OD1  1 ? 
ATOM   4148  N  ND2  . ASN A 1 272 ? 16.014  -19.938 12.233  1   39.578  ? 278  ASN A ND2  1 ? 
ATOM   4149  H  H    . ASN A 1 272 ? 16.223  -16.012 11.509  1   42.115  ? 278  ASN A H    1 c 
ATOM   4150  H  HA   . ASN A 1 272 ? 13.858  -16.693 12.645  1   41.74   ? 278  ASN A HA   1 c 
ATOM   4151  H  HB2  . ASN A 1 272 ? 16.489  -17.589 13.229  1   39.426  ? 278  ASN A HB2  1 c 
ATOM   4152  H  HB3  . ASN A 1 272 ? 15.256  -18.11  14.065  1   39.471  ? 278  ASN A HB3  1 c 
ATOM   4153  H  HD21 . ASN A 1 272 ? 15.863  -20.609 11.673  1   38.817  ? 278  ASN A HD21 1 c 
ATOM   4154  H  HD22 . ASN A 1 272 ? 16.655  -20.004 12.843  1   38.853  ? 278  ASN A HD22 1 c 
ATOM   4155  N  N    . PHE A 1 273 ? 15.808  -14.811 14.35   1   45.196  ? 279  PHE A N    1 ? 
ATOM   4156  C  CA   . PHE A 1 273 ? 16.044  -14.039 15.557  1   45.759  ? 279  PHE A CA   1 ? 
ATOM   4157  C  C    . PHE A 1 273 ? 15.197  -12.77  15.601  1   45.075  ? 279  PHE A C    1 ? 
ATOM   4158  O  O    . PHE A 1 273 ? 14.902  -12.225 16.661  1   42.015  ? 279  PHE A O    1 ? 
ATOM   4159  C  CB   . PHE A 1 273 ? 17.537  -13.681 15.591  1   47.66   ? 279  PHE A CB   1 ? 
ATOM   4160  C  CG   . PHE A 1 273 ? 17.99   -12.887 16.81   1   50.634  ? 279  PHE A CG   1 ? 
ATOM   4161  C  CD1  . PHE A 1 273 ? 18.288  -13.524 18.015  1   58.597  ? 279  PHE A CD1  1 ? 
ATOM   4162  C  CD2  . PHE A 1 273 ? 18.114  -11.502 16.755  1   50.293  ? 279  PHE A CD2  1 ? 
ATOM   4163  C  CE1  . PHE A 1 273 ? 18.691  -12.791 19.135  1   60.567  ? 279  PHE A CE1  1 ? 
ATOM   4164  C  CE2  . PHE A 1 273 ? 18.539  -10.779 17.863  1   50.141  ? 279  PHE A CE2  1 ? 
ATOM   4165  C  CZ   . PHE A 1 273 ? 18.824  -11.42  19.059  1   51.898  ? 279  PHE A CZ   1 ? 
ATOM   4166  H  H    . PHE A 1 273 ? 16.397  -14.709 13.659  1   45.142  ? 279  PHE A H    1 c 
ATOM   4167  H  HA   . PHE A 1 273 ? 15.828  -14.602 16.347  1   45.837  ? 279  PHE A HA   1 c 
ATOM   4168  H  HB2  . PHE A 1 273 ? 18.055  -14.516 15.55   1   47.876  ? 279  PHE A HB2  1 c 
ATOM   4169  H  HB3  . PHE A 1 273 ? 17.749  -13.164 14.783  1   47.861  ? 279  PHE A HB3  1 c 
ATOM   4170  H  HD1  . PHE A 1 273 ? 18.2    -14.462 18.078  1   56.909  ? 279  PHE A HD1  1 c 
ATOM   4171  H  HD2  . PHE A 1 273 ? 17.928  -11.05  15.947  1   50.426  ? 279  PHE A HD2  1 c 
ATOM   4172  H  HE1  . PHE A 1 273 ? 18.892  -13.238 19.942  1   57.783  ? 279  PHE A HE1  1 c 
ATOM   4173  H  HE2  . PHE A 1 273 ? 18.617  -9.84   17.806  1   50.682  ? 279  PHE A HE2  1 c 
ATOM   4174  H  HZ   . PHE A 1 273 ? 19.102  -10.924 19.812  1   53.374  ? 279  PHE A HZ   1 c 
ATOM   4175  N  N    . VAL A 1 274 ? 14.887  -12.225 14.439  1   41.784  ? 280  VAL A N    1 ? 
ATOM   4176  C  CA   . VAL A 1 274 ? 14.222  -10.929 14.393  1   47.606  ? 280  VAL A CA   1 ? 
ATOM   4177  C  C    . VAL A 1 274 ? 12.776  -11.05  14.878  1   40.641  ? 280  VAL A C    1 ? 
ATOM   4178  O  O    . VAL A 1 274 ? 12.157  -12.107 14.777  1   39.795  ? 280  VAL A O    1 ? 
ATOM   4179  C  CB   . VAL A 1 274 ? 14.358  -10.382 12.96   1   47.344  ? 280  VAL A CB   1 ? 
ATOM   4180  C  CG1  . VAL A 1 274 ? 13.133  -9.626  12.483  1   57.601  ? 280  VAL A CG1  1 ? 
ATOM   4181  C  CG2  . VAL A 1 274 ? 15.602  -9.51   12.861  1   49.51   ? 280  VAL A CG2  1 ? 
ATOM   4182  H  H    . VAL A 1 274 ? 15.088  -12.656 13.658  1   43.907  ? 280  VAL A H    1 c 
ATOM   4183  H  HA   . VAL A 1 274 ? 14.696  -10.324 14.996  1   45.035  ? 280  VAL A HA   1 c 
ATOM   4184  H  HB   . VAL A 1 274 ? 14.482  -11.153 12.36   1   49.487  ? 280  VAL A HB   1 c 
ATOM   4185  H  HG11 . VAL A 1 274 ? 13.009  -8.836  13.034  1   54.083  ? 280  VAL A HG11 1 c 
ATOM   4186  H  HG12 . VAL A 1 274 ? 12.351  -10.194 12.552  1   54.185  ? 280  VAL A HG12 1 c 
ATOM   4187  H  HG13 . VAL A 1 274 ? 13.257  -9.358  11.558  1   54.007  ? 280  VAL A HG13 1 c 
ATOM   4188  H  HG21 . VAL A 1 274 ? 15.702  -9.191  11.948  1   48.855  ? 280  VAL A HG21 1 c 
ATOM   4189  H  HG22 . VAL A 1 274 ? 16.384  -10.031 13.109  1   48.855  ? 280  VAL A HG22 1 c 
ATOM   4190  H  HG23 . VAL A 1 274 ? 15.516  -8.75   13.461  1   48.834  ? 280  VAL A HG23 1 c 
ATOM   4191  N  N    . LYS A 1 275 ? 12.224  -9.95   15.38   1   39.052  ? 281  LYS A N    1 ? 
ATOM   4192  C  CA   . LYS A 1 275 ? 10.825  -9.928  15.775  1   44.769  ? 281  LYS A CA   1 ? 
ATOM   4193  C  C    . LYS A 1 275 ? 9.943   -9.84   14.544  1   46.018  ? 281  LYS A C    1 ? 
ATOM   4194  O  O    . LYS A 1 275 ? 10.258  -9.13   13.591  1   48.085  ? 281  LYS A O    1 ? 
ATOM   4195  C  CB   . LYS A 1 275 ? 10.567  -8.858  16.843  1   49.118  ? 281  LYS A CB   1 ? 
ATOM   4196  C  CG   . LYS A 1 275 ? 10.836  -9.521  18.183  1   55.611  ? 281  LYS A CG   1 ? 
ATOM   4197  C  CD   . LYS A 1 275 ? 11.523  -8.743  19.287  1   61.304  ? 281  LYS A CD   1 ? 
ATOM   4198  C  CE   . LYS A 1 275 ? 11.906  -9.779  20.297  1   58.496  ? 281  LYS A CE   1 ? 
ATOM   4199  N  NZ   . LYS A 1 275 ? 12.593  -9.179  21.434  1   67.467  ? 281  LYS A NZ   1 ? 
ATOM   4200  H  H    . LYS A 1 275 ? 12.726  -9.193  15.476  1   40.847  ? 281  LYS A H    1 c 
ATOM   4201  H  HA   . LYS A 1 275 ? 10.63   -10.799 16.204  1   44.662  ? 281  LYS A HA   1 c 
ATOM   4202  H  HB2  . LYS A 1 275 ? 11.168  -8.093  16.723  1   49.423  ? 281  LYS A HB2  1 c 
ATOM   4203  H  HB3  . LYS A 1 275 ? 9.638   -8.548  16.805  1   49.461  ? 281  LYS A HB3  1 c 
ATOM   4204  H  HG2  . LYS A 1 275 ? 9.972   -9.834  18.531  1   55.243  ? 281  LYS A HG2  1 c 
ATOM   4205  H  HG3  . LYS A 1 275 ? 11.37   -10.327 18.011  1   55.149  ? 281  LYS A HG3  1 c 
ATOM   4206  H  HD2  . LYS A 1 275 ? 12.325  -8.29   18.947  1   59.332  ? 281  LYS A HD2  1 c 
ATOM   4207  H  HD3  . LYS A 1 275 ? 10.906  -8.093  19.689  1   59.332  ? 281  LYS A HD3  1 c 
ATOM   4208  H  HE2  . LYS A 1 275 ? 11.109  -10.239 20.615  1   61.117  ? 281  LYS A HE2  1 c 
ATOM   4209  H  HE3  . LYS A 1 275 ? 12.496  -10.438 19.889  1   61.079  ? 281  LYS A HE3  1 c 
ATOM   4210  H  HZ1  . LYS A 1 275 ? 12.04   -8.597  21.854  1   64.562  ? 281  LYS A HZ1  1 c 
ATOM   4211  H  HZ2  . LYS A 1 275 ? 13.33   -8.735  21.148  1   64.548  ? 281  LYS A HZ2  1 c 
ATOM   4212  H  HZ3  . LYS A 1 275 ? 12.843  -9.825  22.018  1   64.562  ? 281  LYS A HZ3  1 c 
ATOM   4213  N  N    . ALA A 1 276 ? 8.832   -10.581 14.609  1   43.591  ? 282  ALA A N    1 ? 
ATOM   4214  C  CA   . ALA A 1 276 ? 7.95    -10.775 13.481  1   42.041  ? 282  ALA A CA   1 ? 
ATOM   4215  C  C    . ALA A 1 276 ? 7.182   -9.504  13.17   1   36.928  ? 282  ALA A C    1 ? 
ATOM   4216  O  O    . ALA A 1 276 ? 6.675   -9.394  12.062  1   43.987  ? 282  ALA A O    1 ? 
ATOM   4217  C  CB   . ALA A 1 276 ? 6.985   -11.921 13.749  1   48.548  ? 282  ALA A CB   1 ? 
ATOM   4218  H  H    . ALA A 1 276 ? 8.614   -10.979 15.403  1   43.839  ? 282  ALA A H    1 c 
ATOM   4219  H  HA   . ALA A 1 276 ? 8.507   -11.001 12.688  1   42.494  ? 282  ALA A HA   1 c 
ATOM   4220  H  HB1  . ALA A 1 276 ? 7.482   -12.743 13.889  1   46.59   ? 282  ALA A HB1  1 c 
ATOM   4221  H  HB2  . ALA A 1 276 ? 6.459   -11.726 14.543  1   46.686  ? 282  ALA A HB2  1 c 
ATOM   4222  H  HB3  . ALA A 1 276 ? 6.389   -12.031 12.989  1   46.572  ? 282  ALA A HB3  1 c 
ATOM   4223  N  N    . ASP A 1 277 ? 7.02    -8.596  14.141  1   36.067  ? 283  ASP A N    1 ? 
ATOM   4224  C  CA   . ASP A 1 277 ? 6.264   -7.386  13.862  1   36.79   ? 283  ASP A CA   1 ? 
ATOM   4225  C  C    . ASP A 1 277 ? 7.061   -6.487  12.914  1   40.419  ? 283  ASP A C    1 ? 
ATOM   4226  O  O    . ASP A 1 277 ? 6.496   -5.582  12.316  1   42.254  ? 283  ASP A O    1 ? 
ATOM   4227  C  CB   . ASP A 1 277 ? 5.884   -6.613  15.107  1   37.436  ? 283  ASP A CB   1 ? 
ATOM   4228  C  CG   . ASP A 1 277 ? 7.024   -6.187  16.019  1   43.792  ? 283  ASP A CG   1 ? 
ATOM   4229  O  OD1  . ASP A 1 277 ? 8.187   -6.102  15.547  1   42.702  ? 283  ASP A OD1  1 ? 
ATOM   4230  O  OD2  . ASP A 1 277 ? 6.724   -5.946  17.194  1   44.266  ? 283  ASP A OD2  1 ? 
ATOM   4231  H  H    . ASP A 1 277 ? 7.364   -8.734  14.976  1   36.603  ? 283  ASP A H    1 c 
ATOM   4232  H  HA   . ASP A 1 277 ? 5.426   -7.643  13.415  1   37.435  ? 283  ASP A HA   1 c 
ATOM   4233  H  HB2  . ASP A 1 277 ? 5.395   -5.808  14.837  1   38.679  ? 283  ASP A HB2  1 c 
ATOM   4234  H  HB3  . ASP A 1 277 ? 5.273   -7.17   15.634  1   38.732  ? 283  ASP A HB3  1 c 
ATOM   4235  N  N    . GLY A 1 278 ? 8.379   -6.678  12.853  1   37.99   ? 284  GLY A N    1 ? 
ATOM   4236  C  CA   . GLY A 1 278 ? 9.175   -6.076  11.79   1   41.719  ? 284  GLY A CA   1 ? 
ATOM   4237  C  C    . GLY A 1 278 ? 9.877   -4.784  12.216  1   37.617  ? 284  GLY A C    1 ? 
ATOM   4238  O  O    . GLY A 1 278 ? 10.506  -4.12   11.386  1   37.134  ? 284  GLY A O    1 ? 
ATOM   4239  H  H    . GLY A 1 278 ? 8.8     -7.177  13.493  1   39.318  ? 284  GLY A H    1 c 
ATOM   4240  H  HA2  . GLY A 1 278 ? 9.848   -6.729  11.491  1   39.951  ? 284  GLY A HA2  1 c 
ATOM   4241  H  HA3  . GLY A 1 278 ? 8.588   -5.885  11.021  1   39.901  ? 284  GLY A HA3  1 c 
ATOM   4242  N  N    . ALA A 1 279 ? 9.753   -4.411  13.497  1   35.093  ? 285  ALA A N    1 ? 
ATOM   4243  C  CA   . ALA A 1 279 ? 10.463  -3.254  13.971  1   37.007  ? 285  ALA A CA   1 ? 
ATOM   4244  C  C    . ALA A 1 279 ? 11.954  -3.57   14.019  1   43.468  ? 285  ALA A C    1 ? 
ATOM   4245  O  O    . ALA A 1 279 ? 12.323  -4.706  14.297  1   37.931  ? 285  ALA A O    1 ? 
ATOM   4246  C  CB   . ALA A 1 279 ? 9.938   -2.836  15.321  1   40.877  ? 285  ALA A CB   1 ? 
ATOM   4247  H  H    . ALA A 1 279 ? 9.223   -4.882  14.073  1   36.209  ? 285  ALA A H    1 c 
ATOM   4248  H  HA   . ALA A 1 279 ? 10.319  -2.512  13.322  1   38.476  ? 285  ALA A HA   1 c 
ATOM   4249  H  HB1  . ALA A 1 279 ? 8.995   -2.616  15.253  1   39.652  ? 285  ALA A HB1  1 c 
ATOM   4250  H  HB2  . ALA A 1 279 ? 10.053  -3.563  15.954  1   39.674  ? 285  ALA A HB2  1 c 
ATOM   4251  H  HB3  . ALA A 1 279 ? 10.427  -2.056  15.635  1   39.677  ? 285  ALA A HB3  1 c 
ATOM   4252  N  N    . CYS A 1 280 ? 12.784  -2.556  13.712  1   45.489  ? 286  CYS A N    1 ? 
ATOM   4253  C  CA   . CYS A 1 280 ? 14.227  -2.625  13.855  1   47.983  ? 286  CYS A CA   1 ? 
ATOM   4254  C  C    . CYS A 1 280 ? 14.571  -2.221  15.287  1   46.996  ? 286  CYS A C    1 ? 
ATOM   4255  O  O    . CYS A 1 280 ? 14.457  -1.045  15.632  1   45.768  ? 286  CYS A O    1 ? 
ATOM   4256  C  CB   . CYS A 1 280 ? 14.93   -1.679  12.874  1   49.656  ? 286  CYS A CB   1 ? 
ATOM   4257  S  SG   . CYS A 1 280 ? 16.746  -1.72   12.899  1   44.673  ? 286  CYS A SG   1 ? 
ATOM   4258  H  H    . CYS A 1 280 ? 12.421  -1.779  13.395  1   45.444  ? 286  CYS A H    1 c 
ATOM   4259  H  HA   . CYS A 1 280 ? 14.519  -3.559  13.7    1   47.609  ? 286  CYS A HA   1 c 
ATOM   4260  H  HB2  . CYS A 1 280 ? 14.636  -1.897  11.963  1   48.199  ? 286  CYS A HB2  1 c 
ATOM   4261  H  HB3  . CYS A 1 280 ? 14.645  -0.759  13.065  1   48.198  ? 286  CYS A HB3  1 c 
ATOM   4262  H  HG   . CYS A 1 280 ? 16.932  -0.881  12.041  0   44.22   ? 286  CYS A HG   1 c 
ATOM   4263  N  N    . GLU A 1 281 ? 15.048  -3.169  16.098  1   54.825  ? 287  GLU A N    1 ? 
ATOM   4264  C  CA   . GLU A 1 281 ? 15.378  -2.861  17.493  1   71.443  ? 287  GLU A CA   1 ? 
ATOM   4265  C  C    . GLU A 1 281 ? 16.572  -1.894  17.57   1   72.831  ? 287  GLU A C    1 ? 
ATOM   4266  O  O    . GLU A 1 281 ? 16.594  -1.039  18.462  1   71.349  ? 287  GLU A O    1 ? 
ATOM   4267  C  CB   . GLU A 1 281 ? 15.566  -4.109  18.364  1   80.462  ? 287  GLU A CB   1 ? 
ATOM   4268  C  CG   . GLU A 1 281 ? 16.963  -4.728  18.32   1   100.261 ? 287  GLU A CG   1 ? 
ATOM   4269  C  CD   . GLU A 1 281 ? 17.419  -5.327  16.995  1   109.615 ? 287  GLU A CD   1 ? 
ATOM   4270  O  OE1  . GLU A 1 281 ? 17.864  -6.498  17.025  1   111.257 ? 287  GLU A OE1  1 ? 
ATOM   4271  O  OE2  . GLU A 1 281 ? 17.347  -4.64   15.946  1   107.661 ? 287  GLU A OE2  1 ? 
ATOM   4272  H  H    . GLU A 1 281 ? 15.169  -4.02   15.788  1   56.144  ? 287  GLU A H    1 c 
ATOM   4273  H  HA   . GLU A 1 281 ? 14.598  -2.385  17.876  1   69.315  ? 287  GLU A HA   1 c 
ATOM   4274  H  HB2  . GLU A 1 281 ? 15.36   -3.876  19.294  1   82.371  ? 287  GLU A HB2  1 c 
ATOM   4275  H  HB3  . GLU A 1 281 ? 14.919  -4.788  18.08   1   82.374  ? 287  GLU A HB3  1 c 
ATOM   4276  H  HG2  . GLU A 1 281 ? 17.613  -4.044  18.58   1   96.953  ? 287  GLU A HG2  1 c 
ATOM   4277  H  HG3  . GLU A 1 281 ? 17.01   -5.432  19.001  1   97.331  ? 287  GLU A HG3  1 c 
ATOM   4278  N  N    . GLU A 1 282 ? 17.532  -1.997  16.619  1   68.907  ? 288  GLU A N    1 ? 
ATOM   4279  C  CA   . GLU A 1 282 ? 18.67   -1.082  16.542  1   61.822  ? 288  GLU A CA   1 ? 
ATOM   4280  C  C    . GLU A 1 282 ? 18.17   0.356   16.322  1   52.601  ? 288  GLU A C    1 ? 
ATOM   4281  O  O    . GLU A 1 282 ? 18.78   1.295   16.799  1   63.158  ? 288  GLU A O    1 ? 
ATOM   4282  C  CB   . GLU A 1 282 ? 19.687  -1.531  15.488  1   66.486  ? 288  GLU A CB   1 ? 
ATOM   4283  C  CG   . GLU A 1 282 ? 20.265  -2.937  15.682  1   70.275  ? 288  GLU A CG   1 ? 
ATOM   4284  C  CD   . GLU A 1 282 ? 21.352  -3.409  14.7    1   75.349  ? 288  GLU A CD   1 ? 
ATOM   4285  O  OE1  . GLU A 1 282 ? 21.194  -4.486  14.073  1   59.928  ? 288  GLU A OE1  1 ? 
ATOM   4286  O  OE2  . GLU A 1 282 ? 22.392  -2.724  14.561  1   73.759  ? 288  GLU A OE2  1 ? 
ATOM   4287  H  H    . GLU A 1 282 ? 17.465  -2.661  15.995  1   68.252  ? 288  GLU A H    1 c 
ATOM   4288  H  HA   . GLU A 1 282 ? 19.131  -1.107  17.418  1   62.13   ? 288  GLU A HA   1 c 
ATOM   4289  H  HB2  . GLU A 1 282 ? 19.261  -1.494  14.607  1   65.932  ? 288  GLU A HB2  1 c 
ATOM   4290  H  HB3  . GLU A 1 282 ? 20.431  -0.895  15.484  1   65.927  ? 288  GLU A HB3  1 c 
ATOM   4291  H  HG2  . GLU A 1 282 ? 20.635  -2.994  16.589  1   70.522  ? 288  GLU A HG2  1 c 
ATOM   4292  H  HG3  . GLU A 1 282 ? 19.529  -3.58   15.642  1   70.599  ? 288  GLU A HG3  1 c 
ATOM   4293  N  N    . GLY A 1 283 ? 17.041  0.542   15.626  1   50.445  ? 289  GLY A N    1 ? 
ATOM   4294  C  CA   . GLY A 1 283 ? 16.447  1.86    15.411  1   44.641  ? 289  GLY A CA   1 ? 
ATOM   4295  C  C    . GLY A 1 283 ? 16.688  2.354   13.982  1   43.535  ? 289  GLY A C    1 ? 
ATOM   4296  O  O    . GLY A 1 283 ? 17.384  1.699   13.205  1   37.793  ? 289  GLY A O    1 ? 
ATOM   4297  H  H    . GLY A 1 283 ? 16.627  -0.183  15.254  1   49.841  ? 289  GLY A H    1 c 
ATOM   4298  H  HA2  . GLY A 1 283 ? 15.478  1.804   15.582  1   45.741  ? 289  GLY A HA2  1 c 
ATOM   4299  H  HA3  . GLY A 1 283 ? 16.832  2.502   16.053  1   45.832  ? 289  GLY A HA3  1 c 
ATOM   4300  N  N    . PRO A 1 284 ? 16.12   3.516   13.586  1   44.039  ? 290  PRO A N    1 ? 
ATOM   4301  C  CA   . PRO A 1 284 ? 16.186  3.995   12.205  1   43.936  ? 290  PRO A CA   1 ? 
ATOM   4302  C  C    . PRO A 1 284 ? 17.581  4.252   11.646  1   43.256  ? 290  PRO A C    1 ? 
ATOM   4303  O  O    . PRO A 1 284 ? 17.782  4.136   10.449  1   45.159  ? 290  PRO A O    1 ? 
ATOM   4304  C  CB   . PRO A 1 284 ? 15.366  5.316   12.209  1   45.894  ? 290  PRO A CB   1 ? 
ATOM   4305  C  CG   . PRO A 1 284 ? 14.531  5.236   13.452  1   47.008  ? 290  PRO A CG   1 ? 
ATOM   4306  C  CD   . PRO A 1 284 ? 15.345  4.418   14.455  1   47.39   ? 290  PRO A CD   1 ? 
ATOM   4307  H  HA   . PRO A 1 284 ? 15.725  3.334   11.631  1   44.174  ? 290  PRO A HA   1 c 
ATOM   4308  H  HB2  . PRO A 1 284 ? 15.963  6.101   12.238  1   45.695  ? 290  PRO A HB2  1 c 
ATOM   4309  H  HB3  . PRO A 1 284 ? 14.796  5.378   11.407  1   45.706  ? 290  PRO A HB3  1 c 
ATOM   4310  H  HG2  . PRO A 1 284 ? 14.351  6.132   13.806  1   46.765  ? 290  PRO A HG2  1 c 
ATOM   4311  H  HG3  . PRO A 1 284 ? 13.676  4.796   13.265  1   46.821  ? 290  PRO A HG3  1 c 
ATOM   4312  H  HD2  . PRO A 1 284 ? 15.938  4.996   14.985  1   46.504  ? 290  PRO A HD2  1 c 
ATOM   4313  H  HD3  . PRO A 1 284 ? 14.756  3.915   15.059  1   46.492  ? 290  PRO A HD3  1 c 
ATOM   4314  N  N    . SER A 1 285 ? 18.52   4.652   12.506  1   42.517  ? 291  SER A N    1 ? 
ATOM   4315  C  CA   . SER A 1 285 ? 19.893  4.886   12.11   1   45.062  ? 291  SER A CA   1 ? 
ATOM   4316  C  C    . SER A 1 285 ? 20.565  3.6     11.643  1   40.738  ? 291  SER A C    1 ? 
ATOM   4317  O  O    . SER A 1 285 ? 21.461  3.648   10.822  1   41.47   ? 291  SER A O    1 ? 
ATOM   4318  C  CB   . SER A 1 285 ? 20.65   5.501   13.261  1   59.479  ? 291  SER A CB   1 ? 
ATOM   4319  O  OG   . SER A 1 285 ? 20.209  4.955   14.503  1   69.244  ? 291  SER A OG   1 ? 
ATOM   4320  H  H    . SER A 1 285 ? 18.289  4.79    13.38   1   43.367  ? 291  SER A H    1 c 
ATOM   4321  H  HA   . SER A 1 285 ? 19.892  5.529   11.356  1   46.062  ? 291  SER A HA   1 c 
ATOM   4322  H  HB2  . SER A 1 285 ? 21.605  5.331   13.151  1   57.781  ? 291  SER A HB2  1 c 
ATOM   4323  H  HB3  . SER A 1 285 ? 20.509  6.467   13.262  1   57.873  ? 291  SER A HB3  1 c 
ATOM   4324  H  HG   . SER A 1 285 ? 20.644  5.252   15.141  0   67.18   ? 291  SER A HG   1 c 
ATOM   4325  N  N    . TYR A 1 286 ? 20.12   2.439   12.117  1   37.267  ? 292  TYR A N    1 ? 
ATOM   4326  C  CA   . TYR A 1 286 ? 20.766  1.192   11.733  1   40.35   ? 292  TYR A CA   1 ? 
ATOM   4327  C  C    . TYR A 1 286 ? 19.95   0.433   10.689  1   36.606  ? 292  TYR A C    1 ? 
ATOM   4328  O  O    . TYR A 1 286 ? 20.393  -0.593  10.171  1   39.388  ? 292  TYR A O    1 ? 
ATOM   4329  C  CB   . TYR A 1 286 ? 20.997  0.356   12.998  1   48.867  ? 292  TYR A CB   1 ? 
ATOM   4330  C  CG   . TYR A 1 286 ? 22.03   0.95    13.949  1   59.903  ? 292  TYR A CG   1 ? 
ATOM   4331  C  CD1  . TYR A 1 286 ? 21.683  2.011   14.78   1   68.154  ? 292  TYR A CD1  1 ? 
ATOM   4332  C  CD2  . TYR A 1 286 ? 23.329  0.454   14.038  1   66.322  ? 292  TYR A CD2  1 ? 
ATOM   4333  C  CE1  . TYR A 1 286 ? 22.591  2.575   15.662  1   72.26   ? 292  TYR A CE1  1 ? 
ATOM   4334  C  CE2  . TYR A 1 286 ? 24.249  1       14.929  1   72.766  ? 292  TYR A CE2  1 ? 
ATOM   4335  C  CZ   . TYR A 1 286 ? 23.875  2.064   15.744  1   80.502  ? 292  TYR A CZ   1 ? 
ATOM   4336  O  OH   . TYR A 1 286 ? 24.706  2.664   16.654  1   71.425  ? 292  TYR A OH   1 ? 
ATOM   4337  H  H    . TYR A 1 286 ? 19.416  2.415   12.7    1   38.88   ? 292  TYR A H    1 c 
ATOM   4338  H  HA   . TYR A 1 286 ? 21.653  1.405   11.339  1   40.433  ? 292  TYR A HA   1 c 
ATOM   4339  H  HB2  . TYR A 1 286 ? 20.141  0.271   13.472  1   49.183  ? 292  TYR A HB2  1 c 
ATOM   4340  H  HB3  . TYR A 1 286 ? 21.288  -0.544  12.731  1   48.92   ? 292  TYR A HB3  1 c 
ATOM   4341  H  HD1  . TYR A 1 286 ? 20.809  2.362   14.736  1   66.826  ? 292  TYR A HD1  1 c 
ATOM   4342  H  HD2  . TYR A 1 286 ? 23.588  -0.272  13.493  1   66.219  ? 292  TYR A HD2  1 c 
ATOM   4343  H  HE1  . TYR A 1 286 ? 22.33   3.289   16.218  1   72.72   ? 292  TYR A HE1  1 c 
ATOM   4344  H  HE2  . TYR A 1 286 ? 25.124  0.653   14.979  1   72.699  ? 292  TYR A HE2  1 c 
ATOM   4345  H  HH   . TYR A 1 286 ? 24.665  2.213   17.419  0   69.6    ? 292  TYR A HH   1 c 
ATOM   4346  N  N    . TRP A 1 287 ? 18.741  0.915   10.368  1   35.714  ? 293  TRP A N    1 ? 
ATOM   4347  C  CA   . TRP A 1 287 ? 17.85   0.127   9.539   1   32.495  ? 293  TRP A CA   1 ? 
ATOM   4348  C  C    . TRP A 1 287 ? 18.549  -0.267  8.233   1   35.063  ? 293  TRP A C    1 ? 
ATOM   4349  O  O    . TRP A 1 287 ? 18.394  -1.381  7.743   1   32.225  ? 293  TRP A O    1 ? 
ATOM   4350  C  CB   . TRP A 1 287 ? 16.565  0.924   9.264   1   35.955  ? 293  TRP A CB   1 ? 
ATOM   4351  C  CG   . TRP A 1 287 ? 15.69   0.302   8.201   1   29.476  ? 293  TRP A CG   1 ? 
ATOM   4352  C  CD1  . TRP A 1 287 ? 14.765  -0.677  8.414   1   33.204  ? 293  TRP A CD1  1 ? 
ATOM   4353  C  CD2  . TRP A 1 287 ? 15.686  0.582   6.789   1   29.409  ? 293  TRP A CD2  1 ? 
ATOM   4354  N  NE1  . TRP A 1 287 ? 14.154  -1.001  7.234   1   34.465  ? 293  TRP A NE1  1 ? 
ATOM   4355  C  CE2  . TRP A 1 287 ? 14.712  -0.263  6.218   1   31.108  ? 293  TRP A CE2  1 ? 
ATOM   4356  C  CE3  . TRP A 1 287 ? 16.417  1.447   5.949   1   30.741  ? 293  TRP A CE3  1 ? 
ATOM   4357  C  CZ2  . TRP A 1 287 ? 14.454  -0.273  4.851   1   27.619  ? 293  TRP A CZ2  1 ? 
ATOM   4358  C  CZ3  . TRP A 1 287 ? 16.189  1.42    4.59    1   27.687  ? 293  TRP A CZ3  1 ? 
ATOM   4359  C  CH2  . TRP A 1 287 ? 15.216  0.568   4.051   1   30.82   ? 293  TRP A CH2  1 ? 
ATOM   4360  H  H    . TRP A 1 287 ? 18.472  1.736   10.663  1   35.273  ? 293  TRP A H    1 c 
ATOM   4361  H  HA   . TRP A 1 287 ? 17.608  -0.701  10.034  1   34.183  ? 293  TRP A HA   1 c 
ATOM   4362  H  HB2  . TRP A 1 287 ? 16.054  0.992   10.099  1   33.573  ? 293  TRP A HB2  1 c 
ATOM   4363  H  HB3  . TRP A 1 287 ? 16.815  1.83    8.982   1   33.58   ? 293  TRP A HB3  1 c 
ATOM   4364  H  HD1  . TRP A 1 287 ? 14.538  -1.045  9.253   1   32.578  ? 293  TRP A HD1  1 c 
ATOM   4365  H  HE1  . TRP A 1 287 ? 13.532  -1.607  7.138   1   33.278  ? 293  TRP A HE1  1 c 
ATOM   4366  H  HE3  . TRP A 1 287 ? 17.084  2.006   6.31    1   29.703  ? 293  TRP A HE3  1 c 
ATOM   4367  H  HZ2  . TRP A 1 287 ? 13.808  -0.849  4.481   1   29.136  ? 293  TRP A HZ2  1 c 
ATOM   4368  H  HZ3  . TRP A 1 287 ? 16.668  2.001   4.023   1   29.097  ? 293  TRP A HZ3  1 c 
ATOM   4369  H  HH2  . TRP A 1 287 ? 15.05   0.59    3.125   1   29.329  ? 293  TRP A HH2  1 c 
ATOM   4370  N  N    . GLY A 1 288 ? 19.329  0.657   7.652   1   30.63   ? 294  GLY A N    1 ? 
ATOM   4371  C  CA   . GLY A 1 288 ? 19.84   0.488   6.304   1   30.218  ? 294  GLY A CA   1 ? 
ATOM   4372  C  C    . GLY A 1 288 ? 20.87   -0.632  6.16    1   29.863  ? 294  GLY A C    1 ? 
ATOM   4373  O  O    . GLY A 1 288 ? 21.057  -1.111  5.044   1   31.782  ? 294  GLY A O    1 ? 
ATOM   4374  H  H    . GLY A 1 288 ? 19.539  1.421   8.107   1   31.597  ? 294  GLY A H    1 c 
ATOM   4375  H  HA2  . GLY A 1 288 ? 19.081  0.305   5.702   1   30.252  ? 294  GLY A HA2  1 c 
ATOM   4376  H  HA3  . GLY A 1 288 ? 20.247  1.336   6.017   1   30.317  ? 294  GLY A HA3  1 c 
ATOM   4377  N  N    . HIS A 1 289 ? 21.525  -0.994  7.282   1   31.499  ? 295  HIS A N    1 ? 
ATOM   4378  C  CA   . HIS A 1 289 ? 22.508  -2.059  7.335   1   35.575  ? 295  HIS A CA   1 ? 
ATOM   4379  C  C    . HIS A 1 289 ? 22.008  -3.313  8.064   1   37.435  ? 295  HIS A C    1 ? 
ATOM   4380  O  O    . HIS A 1 289 ? 22.717  -4.33   8.117   1   41.319  ? 295  HIS A O    1 ? 
ATOM   4381  C  CB   . HIS A 1 289 ? 23.842  -1.484  7.833   1   34.288  ? 295  HIS A CB   1 ? 
ATOM   4382  C  CG   . HIS A 1 289 ? 24.423  -0.646  6.734   1   33.158  ? 295  HIS A CG   1 ? 
ATOM   4383  N  ND1  . HIS A 1 289 ? 25.18   -1.211  5.722   1   34.884  ? 295  HIS A ND1  1 ? 
ATOM   4384  C  CD2  . HIS A 1 289 ? 24.218  0.65    6.393   1   33.645  ? 295  HIS A CD2  1 ? 
ATOM   4385  C  CE1  . HIS A 1 289 ? 25.509  -0.251  4.847   1   38.531  ? 295  HIS A CE1  1 ? 
ATOM   4386  N  NE2  . HIS A 1 289 ? 24.893  0.882   5.205   1   36.09   ? 295  HIS A NE2  1 ? 
ATOM   4387  H  H    . HIS A 1 289 ? 21.355  -0.532  8.052   1   31.987  ? 295  HIS A H    1 c 
ATOM   4388  H  HA   . HIS A 1 289 ? 22.668  -2.321  6.395   1   34.74   ? 295  HIS A HA   1 c 
ATOM   4389  H  HB2  . HIS A 1 289 ? 23.683  -0.927  8.626   1   34.306  ? 295  HIS A HB2  1 c 
ATOM   4390  H  HB3  . HIS A 1 289 ? 24.456  -2.219  8.049   1   34.306  ? 295  HIS A HB3  1 c 
ATOM   4391  H  HD1  . HIS A 1 289 ? 25.392  -2.067  5.65    0   35.28   ? 295  HIS A HD1  1 c 
ATOM   4392  H  HD2  . HIS A 1 289 ? 23.712  1.281   6.867   1   34.098  ? 295  HIS A HD2  1 c 
ATOM   4393  H  HE1  . HIS A 1 289 ? 26.033  -0.372  4.082   1   37.039  ? 295  HIS A HE1  1 c 
ATOM   4394  H  HE2  . HIS A 1 289 ? 24.92   1.633   4.771   0   36.29   ? 295  HIS A HE2  1 c 
ATOM   4395  N  N    . ALA A 1 290 ? 20.807  -3.281  8.613   1   33.206  ? 296  ALA A N    1 ? 
ATOM   4396  C  CA   . ALA A 1 290 ? 20.246  -4.461  9.261   1   33.004  ? 296  ALA A CA   1 ? 
ATOM   4397  C  C    . ALA A 1 290 ? 19.202  -5.042  8.323   1   32.016  ? 296  ALA A C    1 ? 
ATOM   4398  O  O    . ALA A 1 290 ? 19.545  -5.82   7.431   1   38.335  ? 296  ALA A O    1 ? 
ATOM   4399  C  CB   . ALA A 1 290 ? 19.703  -4.12   10.651  1   32.84   ? 296  ALA A CB   1 ? 
ATOM   4400  H  H    . ALA A 1 290 ? 20.314  -2.511  8.593   1   34.099  ? 296  ALA A H    1 c 
ATOM   4401  H  HA   . ALA A 1 290 ? 20.971  -5.136  9.363   1   32.905  ? 296  ALA A HA   1 c 
ATOM   4402  H  HB1  . ALA A 1 290 ? 20.443  -3.923  11.251  1   32.934  ? 296  ALA A HB1  1 c 
ATOM   4403  H  HB2  . ALA A 1 290 ? 19.122  -3.343  10.595  1   32.89   ? 296  ALA A HB2  1 c 
ATOM   4404  H  HB3  . ALA A 1 290 ? 19.199  -4.874  11      1   32.897  ? 296  ALA A HB3  1 c 
ATOM   4405  N  N    . ALA A 1 291 ? 17.97   -4.531  8.367   1   31.093  ? 297  ALA A N    1 ? 
ATOM   4406  C  CA   . ALA A 1 291 ? 16.945  -5.021  7.447   1   32.546  ? 297  ALA A CA   1 ? 
ATOM   4407  C  C    . ALA A 1 291 ? 17.305  -4.655  5.999   1   31.432  ? 297  ALA A C    1 ? 
ATOM   4408  O  O    . ALA A 1 291 ? 16.961  -5.35   5.037   1   32.266  ? 297  ALA A O    1 ? 
ATOM   4409  C  CB   . ALA A 1 291 ? 15.588  -4.481  7.854   1   34.461  ? 297  ALA A CB   1 ? 
ATOM   4410  H  H    . ALA A 1 291 ? 17.76   -3.869  8.961   1   31.694  ? 297  ALA A H    1 c 
ATOM   4411  H  HA   . ALA A 1 291 ? 16.924  -6.016  7.514   1   32.419  ? 297  ALA A HA   1 c 
ATOM   4412  H  HB1  . ALA A 1 291 ? 15.311  -4.889  8.692   1   33.968  ? 297  ALA A HB1  1 c 
ATOM   4413  H  HB2  . ALA A 1 291 ? 15.639  -3.517  7.968   1   33.889  ? 297  ALA A HB2  1 c 
ATOM   4414  H  HB3  . ALA A 1 291 ? 14.933  -4.689  7.166   1   33.901  ? 297  ALA A HB3  1 c 
ATOM   4415  N  N    . GLY A 1 292 ? 17.964  -3.518  5.821   1   30.37   ? 298  GLY A N    1 ? 
ATOM   4416  C  CA   . GLY A 1 292 ? 18.417  -3.098  4.495   1   28.381  ? 298  GLY A CA   1 ? 
ATOM   4417  C  C    . GLY A 1 292 ? 19.476  -4.008  3.845   1   25.638  ? 298  GLY A C    1 ? 
ATOM   4418  O  O    . GLY A 1 292 ? 19.465  -4.17   2.639   1   28.59   ? 298  GLY A O    1 ? 
ATOM   4419  H  H    . GLY A 1 292 ? 18.134  -2.974  6.536   1   30.19   ? 298  GLY A H    1 c 
ATOM   4420  H  HA2  . GLY A 1 292 ? 17.632  -3.051  3.9     1   28.223  ? 298  GLY A HA2  1 c 
ATOM   4421  H  HA3  . GLY A 1 292 ? 18.783  -2.186  4.567   1   28.222  ? 298  GLY A HA3  1 c 
ATOM   4422  N  N    . LYS A 1 293 ? 20.408  -4.578  4.614   1   25.443  ? 299  LYS A N    1 ? 
ATOM   4423  C  CA   . LYS A 1 293 ? 21.366  -5.535  4.061   1   28.132  ? 299  LYS A CA   1 ? 
ATOM   4424  C  C    . LYS A 1 293 ? 20.777  -6.929  3.913   1   29.74   ? 299  LYS A C    1 ? 
ATOM   4425  O  O    . LYS A 1 293 ? 21.229  -7.678  3.046   1   34.422  ? 299  LYS A O    1 ? 
ATOM   4426  C  CB   . LYS A 1 293 ? 22.666  -5.644  4.86    1   29.957  ? 299  LYS A CB   1 ? 
ATOM   4427  C  CG   . LYS A 1 293 ? 23.644  -4.512  4.516   1   29.601  ? 299  LYS A CG   1 ? 
ATOM   4428  C  CD   . LYS A 1 293 ? 24.22   -4.717  3.115   1   30.047  ? 299  LYS A CD   1 ? 
ATOM   4429  C  CE   . LYS A 1 293 ? 25.2    -3.664  2.614   1   32.899  ? 299  LYS A CE   1 ? 
ATOM   4430  N  NZ   . LYS A 1 293 ? 25.462  -3.894  1.177   1   30.851  ? 299  LYS A NZ   1 ? 
ATOM   4431  H  H    . LYS A 1 293 ? 20.454  -4.367  5.502   1   26.118  ? 299  LYS A H    1 c 
ATOM   4432  H  HA   . LYS A 1 293 ? 21.606  -5.223  3.155   1   28.222  ? 299  LYS A HA   1 c 
ATOM   4433  H  HB2  . LYS A 1 293 ? 22.462  -5.608  5.819   1   29.487  ? 299  LYS A HB2  1 c 
ATOM   4434  H  HB3  . LYS A 1 293 ? 23.096  -6.504  4.671   1   29.47   ? 299  LYS A HB3  1 c 
ATOM   4435  H  HG2  . LYS A 1 293 ? 23.171  -3.653  4.555   1   29.82   ? 299  LYS A HG2  1 c 
ATOM   4436  H  HG3  . LYS A 1 293 ? 24.372  -4.502  5.174   1   29.806  ? 299  LYS A HG3  1 c 
ATOM   4437  H  HD2  . LYS A 1 293 ? 24.668  -5.59   3.097   1   30.567  ? 299  LYS A HD2  1 c 
ATOM   4438  H  HD3  . LYS A 1 293 ? 23.476  -4.769  2.479   1   30.546  ? 299  LYS A HD3  1 c 
ATOM   4439  H  HE2  . LYS A 1 293 ? 24.824  -2.774  2.736   1   31.76   ? 299  LYS A HE2  1 c 
ATOM   4440  H  HE3  . LYS A 1 293 ? 26.036  -3.72   3.109   1   31.79   ? 299  LYS A HE3  1 c 
ATOM   4441  H  HZ1  . LYS A 1 293 ? 24.726  -3.679  0.693   1   31.47   ? 299  LYS A HZ1  1 c 
ATOM   4442  H  HZ2  . LYS A 1 293 ? 25.667  -4.766  1.037   1   31.464  ? 299  LYS A HZ2  1 c 
ATOM   4443  H  HZ3  . LYS A 1 293 ? 26.156  -3.381  0.91    1   31.485  ? 299  LYS A HZ3  1 c 
ATOM   4444  N  N    . MET A 1 294 ? 19.782  -7.265  4.736   1   29.653  ? 300  MET A N    1 ? 
ATOM   4445  C  CA   . MET A 1 294 ? 19.022  -8.486  4.532   1   33.047  ? 300  MET A CA   1 ? 
ATOM   4446  C  C    . MET A 1 294 ? 18.374  -8.413  3.164   1   31.373  ? 300  MET A C    1 ? 
ATOM   4447  O  O    . MET A 1 294 ? 18.421  -9.384  2.438   1   35.478  ? 300  MET A O    1 ? 
ATOM   4448  C  CB   . MET A 1 294 ? 17.916  -8.685  5.57    1   32.109  ? 300  MET A CB   1 ? 
ATOM   4449  C  CG   . MET A 1 294 ? 16.973  -9.824  5.214   1   36.209  ? 300  MET A CG   1 ? 
ATOM   4450  S  SD   . MET A 1 294 ? 15.582  -9.89   6.354   1   35.581  ? 300  MET A SD   1 ? 
ATOM   4451  C  CE   . MET A 1 294 ? 14.494  -8.63   5.687   1   43.429  ? 300  MET A CE   1 ? 
ATOM   4452  H  H    . MET A 1 294 ? 19.577  -6.728  5.447   1   30.364  ? 300  MET A H    1 c 
ATOM   4453  H  HA   . MET A 1 294 ? 19.646  -9.255  4.555   1   31.914  ? 300  MET A HA   1 c 
ATOM   4454  H  HB2  . MET A 1 294 ? 18.328  -8.868  6.441   1   33.217  ? 300  MET A HB2  1 c 
ATOM   4455  H  HB3  . MET A 1 294 ? 17.401  -7.854  5.648   1   33.213  ? 300  MET A HB3  1 c 
ATOM   4456  H  HG2  . MET A 1 294 ? 16.632  -9.703  4.307   1   35.049  ? 300  MET A HG2  1 c 
ATOM   4457  H  HG3  . MET A 1 294 ? 17.456  -10.673 5.249   1   35.066  ? 300  MET A HG3  1 c 
ATOM   4458  H  HE1  . MET A 1 294 ? 13.645  -8.644  6.167   1   41.277  ? 300  MET A HE1  1 c 
ATOM   4459  H  HE2  . MET A 1 294 ? 14.912  -7.754  5.789   1   41.29   ? 300  MET A HE2  1 c 
ATOM   4460  H  HE3  . MET A 1 294 ? 14.336  -8.806  4.741   1   41.239  ? 300  MET A HE3  1 c 
ATOM   4461  N  N    . TYR A 1 295 ? 17.738  -7.253  2.872   1   33.408  ? 301  TYR A N    1 ? 
ATOM   4462  C  CA   . TYR A 1 295 ? 17.04   -7.009  1.632   1   32.792  ? 301  TYR A CA   1 ? 
ATOM   4463  C  C    . TYR A 1 295 ? 18.046  -7.219  0.501   1   29.314  ? 301  TYR A C    1 ? 
ATOM   4464  O  O    . TYR A 1 295 ? 17.713  -7.762  -0.545  1   31.831  ? 301  TYR A O    1 ? 
ATOM   4465  C  CB   . TYR A 1 295 ? 16.338  -5.634  1.522   1   31.976  ? 301  TYR A CB   1 ? 
ATOM   4466  C  CG   . TYR A 1 295 ? 16.262  -5.271  0.06    1   28.313  ? 301  TYR A CG   1 ? 
ATOM   4467  C  CD1  . TYR A 1 295 ? 15.397  -5.969  -0.775  1   30.452  ? 301  TYR A CD1  1 ? 
ATOM   4468  C  CD2  . TYR A 1 295 ? 17.043  -4.268  -0.516  1   33.474  ? 301  TYR A CD2  1 ? 
ATOM   4469  C  CE1  . TYR A 1 295 ? 15.354  -5.742  -2.143  1   27.364  ? 301  TYR A CE1  1 ? 
ATOM   4470  C  CE2  . TYR A 1 295 ? 17.022  -4.039  -1.902  1   28.286  ? 301  TYR A CE2  1 ? 
ATOM   4471  C  CZ   . TYR A 1 295 ? 16.184  -4.799  -2.719  1   28.351  ? 301  TYR A CZ   1 ? 
ATOM   4472  O  OH   . TYR A 1 295 ? 16.082  -4.663  -4.092  1   28.205  ? 301  TYR A OH   1 ? 
ATOM   4473  H  H    . TYR A 1 295 ? 17.743  -6.586  3.498   1   32.741  ? 301  TYR A H    1 c 
ATOM   4474  H  HA   . TYR A 1 295 ? 16.339  -7.709  1.545   1   32.091  ? 301  TYR A HA   1 c 
ATOM   4475  H  HB2  . TYR A 1 295 ? 15.432  -5.696  1.899   1   31.272  ? 301  TYR A HB2  1 c 
ATOM   4476  H  HB3  . TYR A 1 295 ? 16.861  -4.958  2.008   1   31.279  ? 301  TYR A HB3  1 c 
ATOM   4477  H  HD1  . TYR A 1 295 ? 14.873  -6.665  -0.412  1   29.256  ? 301  TYR A HD1  1 c 
ATOM   4478  H  HD2  . TYR A 1 295 ? 17.66   -3.796  0.02    1   30.929  ? 301  TYR A HD2  1 c 
ATOM   4479  H  HE1  . TYR A 1 295 ? 14.79   -6.263  -2.688  1   28.358  ? 301  TYR A HE1  1 c 
ATOM   4480  H  HE2  . TYR A 1 295 ? 17.582  -3.384  -2.281  1   29.412  ? 301  TYR A HE2  1 c 
ATOM   4481  H  HH   . TYR A 1 295 ? 15.483  -4.073  -4.289  0   29.01   ? 301  TYR A HH   1 c 
ATOM   4482  N  N    . ASP A 1 296 ? 19.26   -6.728  0.697   1   30.585  ? 302  ASP A N    1 ? 
ATOM   4483  C  CA   . ASP A 1 296 ? 20.252  -6.791  -0.364  1   32.589  ? 302  ASP A CA   1 ? 
ATOM   4484  C  C    . ASP A 1 296 ? 20.661  -8.23   -0.601  1   30      ? 302  ASP A C    1 ? 
ATOM   4485  O  O    . ASP A 1 296 ? 20.757  -8.635  -1.738  1   35.735  ? 302  ASP A O    1 ? 
ATOM   4486  C  CB   . ASP A 1 296 ? 21.544  -6.067  -0.041  1   30.457  ? 302  ASP A CB   1 ? 
ATOM   4487  C  CG   . ASP A 1 296 ? 21.515  -4.556  -0.064  1   27.864  ? 302  ASP A CG   1 ? 
ATOM   4488  O  OD1  . ASP A 1 296 ? 20.421  -3.983  -0.204  1   35.404  ? 302  ASP A OD1  1 ? 
ATOM   4489  O  OD2  . ASP A 1 296 ? 22.598  -3.965  0.084   1   31.662  ? 302  ASP A OD2  1 ? 
ATOM   4490  H  H    . ASP A 1 296 ? 19.478  -6.331  1.49    1   30.741  ? 302  ASP A H    1 c 
ATOM   4491  H  HA   . ASP A 1 296 ? 19.863  -6.422  -1.189  1   31.349  ? 302  ASP A HA   1 c 
ATOM   4492  H  HB2  . ASP A 1 296 ? 21.837  -6.343  0.852   1   30.33   ? 302  ASP A HB2  1 c 
ATOM   4493  H  HB3  . ASP A 1 296 ? 22.231  -6.355  -0.678  1   30.302  ? 302  ASP A HB3  1 c 
ATOM   4494  N  N    . TYR A 1 297 ? 20.943  -8.949  0.474   1   31.759  ? 303  TYR A N    1 ? 
ATOM   4495  C  CA   . TYR A 1 297 ? 21.187  -10.392 0.432   1   34.544  ? 303  TYR A CA   1 ? 
ATOM   4496  C  C    . TYR A 1 297 ? 20.057  -11.058 -0.363  1   30.718  ? 303  TYR A C    1 ? 
ATOM   4497  O  O    . TYR A 1 297 ? 20.34   -11.789 -1.294  1   32.713  ? 303  TYR A O    1 ? 
ATOM   4498  C  CB   . TYR A 1 297 ? 21.399  -11.001 1.841   1   29.744  ? 303  TYR A CB   1 ? 
ATOM   4499  C  CG   . TYR A 1 297 ? 21.508  -12.518 1.804   1   33.603  ? 303  TYR A CG   1 ? 
ATOM   4500  C  CD1  . TYR A 1 297 ? 22.734  -13.146 1.62    1   28.661  ? 303  TYR A CD1  1 ? 
ATOM   4501  C  CD2  . TYR A 1 297 ? 20.361  -13.32  1.85    1   34.922  ? 303  TYR A CD2  1 ? 
ATOM   4502  C  CE1  . TYR A 1 297 ? 22.82   -14.528 1.556   1   33.707  ? 303  TYR A CE1  1 ? 
ATOM   4503  C  CE2  . TYR A 1 297 ? 20.43   -14.704 1.77    1   33.2    ? 303  TYR A CE2  1 ? 
ATOM   4504  C  CZ   . TYR A 1 297 ? 21.668  -15.306 1.618   1   38.818  ? 303  TYR A CZ   1 ? 
ATOM   4505  O  OH   . TYR A 1 297 ? 21.724  -16.658 1.534   1   33.032  ? 303  TYR A OH   1 ? 
ATOM   4506  H  H    . TYR A 1 297 ? 20.993  -8.527  1.283   1   31.89   ? 303  TYR A H    1 c 
ATOM   4507  H  HA   . TYR A 1 297 ? 22.029  -10.532 -0.077  1   32.367  ? 303  TYR A HA   1 c 
ATOM   4508  H  HB2  . TYR A 1 297 ? 22.22   -10.628 2.228   1   31.621  ? 303  TYR A HB2  1 c 
ATOM   4509  H  HB3  . TYR A 1 297 ? 20.642  -10.746 2.413   1   31.646  ? 303  TYR A HB3  1 c 
ATOM   4510  H  HD1  . TYR A 1 297 ? 23.522  -12.63  1.577   1   30.951  ? 303  TYR A HD1  1 c 
ATOM   4511  H  HD2  . TYR A 1 297 ? 19.516  -12.909 1.948   1   34.162  ? 303  TYR A HD2  1 c 
ATOM   4512  H  HE1  . TYR A 1 297 ? 23.659  -14.942 1.446   1   33.512  ? 303  TYR A HE1  1 c 
ATOM   4513  H  HE2  . TYR A 1 297 ? 19.648  -15.227 1.818   1   34.759  ? 303  TYR A HE2  1 c 
ATOM   4514  H  HH   . TYR A 1 297 ? 21.815  -16.998 2.321   0   32.34   ? 303  TYR A HH   1 c 
ATOM   4515  N  N    . LEU A 1 298 ? 18.789  -10.71  -0.1    1   33.407  ? 304  LEU A N    1 ? 
ATOM   4516  C  CA   . LEU A 1 298 ? 17.647  -11.396 -0.718  1   31.097  ? 304  LEU A CA   1 ? 
ATOM   4517  C  C    . LEU A 1 298 ? 17.539  -10.989 -2.191  1   34.335  ? 304  LEU A C    1 ? 
ATOM   4518  O  O    . LEU A 1 298 ? 17.202  -11.789 -3.073  1   31.343  ? 304  LEU A O    1 ? 
ATOM   4519  C  CB   . LEU A 1 298 ? 16.371  -11.092 0.049   1   30.791  ? 304  LEU A CB   1 ? 
ATOM   4520  C  CG   . LEU A 1 298 ? 16.277  -11.669 1.469   1   35.012  ? 304  LEU A CG   1 ? 
ATOM   4521  C  CD1  . LEU A 1 298 ? 15.079  -11.117 2.216   1   38.013  ? 304  LEU A CD1  1 ? 
ATOM   4522  C  CD2  . LEU A 1 298 ? 16.186  -13.209 1.445   1   33.811  ? 304  LEU A CD2  1 ? 
ATOM   4523  H  H    . LEU A 1 298 ? 18.626  -10.031 0.489   1   32.195  ? 304  LEU A H    1 c 
ATOM   4524  H  HA   . LEU A 1 298 ? 17.819  -12.371 -0.681  1   32.069  ? 304  LEU A HA   1 c 
ATOM   4525  H  HB2  . LEU A 1 298 ? 16.274  -10.114 0.106   1   31.776  ? 304  LEU A HB2  1 c 
ATOM   4526  H  HB3  . LEU A 1 298 ? 15.61   -11.433 -0.475  1   31.785  ? 304  LEU A HB3  1 c 
ATOM   4527  H  HG   . LEU A 1 298 ? 17.096  -11.417 1.965   1   34.508  ? 304  LEU A HG   1 c 
ATOM   4528  H  HD11 . LEU A 1 298 ? 15.16   -10.152 2.291   1   37.093  ? 304  LEU A HD11 1 c 
ATOM   4529  H  HD12 . LEU A 1 298 ? 15.042  -11.509 3.105   1   37.077  ? 304  LEU A HD12 1 c 
ATOM   4530  H  HD13 . LEU A 1 298 ? 14.265  -11.336 1.732   1   37.093  ? 304  LEU A HD13 1 c 
ATOM   4531  H  HD21 . LEU A 1 298 ? 17.009  -13.578 1.085   1   34.13   ? 304  LEU A HD21 1 c 
ATOM   4532  H  HD22 . LEU A 1 298 ? 15.438  -13.482 0.887   1   34.154  ? 304  LEU A HD22 1 c 
ATOM   4533  H  HD23 . LEU A 1 298 ? 16.052  -13.54  2.349   1   34.168  ? 304  LEU A HD23 1 c 
ATOM   4534  N  N    . GLN A 1 299 ? 17.901  -9.748  -2.505  1   28.443  ? 305  GLN A N    1 ? 
ATOM   4535  C  CA   . GLN A 1 299 ? 17.907  -9.388  -3.909  1   31.42   ? 305  GLN A CA   1 ? 
ATOM   4536  C  C    . GLN A 1 299 ? 18.934  -10.27  -4.633  1   29.917  ? 305  GLN A C    1 ? 
ATOM   4537  O  O    . GLN A 1 299 ? 18.687  -10.819 -5.699  1   34.718  ? 305  GLN A O    1 ? 
ATOM   4538  C  CB   . GLN A 1 299 ? 18.122  -7.871  -4.006  1   34.645  ? 305  GLN A CB   1 ? 
ATOM   4539  C  CG   . GLN A 1 299 ? 17.865  -7.28   -5.385  1   34.739  ? 305  GLN A CG   1 ? 
ATOM   4540  C  CD   . GLN A 1 299 ? 16.425  -7.448  -5.859  1   37.708  ? 305  GLN A CD   1 ? 
ATOM   4541  O  OE1  . GLN A 1 299 ? 15.479  -6.806  -5.381  1   35.923  ? 305  GLN A OE1  1 ? 
ATOM   4542  N  NE2  . GLN A 1 299 ? 16.248  -8.276  -6.87   1   34.492  ? 305  GLN A NE2  1 ? 
ATOM   4543  H  H    . GLN A 1 299 ? 18.133  -9.135  -1.867  1   30.499  ? 305  GLN A H    1 c 
ATOM   4544  H  HA   . GLN A 1 299 ? 17.011  -9.591  -4.28   1   31.139  ? 305  GLN A HA   1 c 
ATOM   4545  H  HB2  . GLN A 1 299 ? 17.529  -7.432  -3.36   1   33.847  ? 305  GLN A HB2  1 c 
ATOM   4546  H  HB3  . GLN A 1 299 ? 19.044  -7.671  -3.744  1   33.895  ? 305  GLN A HB3  1 c 
ATOM   4547  H  HG2  . GLN A 1 299 ? 18.078  -6.323  -5.368  1   35.373  ? 305  GLN A HG2  1 c 
ATOM   4548  H  HG3  . GLN A 1 299 ? 18.466  -7.706  -6.034  1   35.367  ? 305  GLN A HG3  1 c 
ATOM   4549  H  HE21 . GLN A 1 299 ? 15.475  -8.276  -7.309  1   35.454  ? 305  GLN A HE21 1 c 
ATOM   4550  H  HE22 . GLN A 1 299 ? 16.895  -8.833  -7.112  1   35.446  ? 305  GLN A HE22 1 c 
ATOM   4551  N  N    . ILE A 1 300 ? 20.126  -10.343 -4.061  1   34.651  ? 306  ILE A N    1 ? 
ATOM   4552  C  CA   . ILE A 1 300 ? 21.271  -11.011 -4.656  1   33.862  ? 306  ILE A CA   1 ? 
ATOM   4553  C  C    . ILE A 1 300 ? 20.946  -12.484 -4.854  1   25.658  ? 306  ILE A C    1 ? 
ATOM   4554  O  O    . ILE A 1 300 ? 21.353  -13.081 -5.845  1   29.623  ? 306  ILE A O    1 ? 
ATOM   4555  C  CB   . ILE A 1 300 ? 22.531  -10.783 -3.783  1   33.702  ? 306  ILE A CB   1 ? 
ATOM   4556  C  CG1  . ILE A 1 300 ? 23.033  -9.315  -3.873  1   32.253  ? 306  ILE A CG1  1 ? 
ATOM   4557  C  CG2  . ILE A 1 300 ? 23.657  -11.755 -4.143  1   33.649  ? 306  ILE A CG2  1 ? 
ATOM   4558  C  CD1  . ILE A 1 300 ? 23.712  -8.839  -2.595  1   31.636  ? 306  ILE A CD1  1 ? 
ATOM   4559  H  H    . ILE A 1 300 ? 20.239  -9.944  -3.247  1   33.24   ? 306  ILE A H    1 c 
ATOM   4560  H  HA   . ILE A 1 300 ? 21.433  -10.612 -5.533  1   32.271  ? 306  ILE A HA   1 c 
ATOM   4561  H  HB   . ILE A 1 300 ? 22.281  -10.953 -2.854  1   33.424  ? 306  ILE A HB   1 c 
ATOM   4562  H  HG12 . ILE A 1 300 ? 23.665  -9.239  -4.616  1   32.448  ? 306  ILE A HG12 1 c 
ATOM   4563  H  HG13 . ILE A 1 300 ? 22.271  -8.73   -4.064  1   32.462  ? 306  ILE A HG13 1 c 
ATOM   4564  H  HG21 . ILE A 1 300 ? 24.392  -11.648 -3.516  1   33.63   ? 306  ILE A HG21 1 c 
ATOM   4565  H  HG22 . ILE A 1 300 ? 23.973  -11.568 -5.043  1   33.627  ? 306  ILE A HG22 1 c 
ATOM   4566  H  HG23 . ILE A 1 300 ? 23.331  -12.667 -4.102  1   33.523  ? 306  ILE A HG23 1 c 
ATOM   4567  H  HD11 . ILE A 1 300 ? 23.15   -9.036  -1.822  1   31.836  ? 306  ILE A HD11 1 c 
ATOM   4568  H  HD12 . ILE A 1 300 ? 23.866  -7.876  -2.646  1   31.816  ? 306  ILE A HD12 1 c 
ATOM   4569  H  HD13 . ILE A 1 300 ? 24.568  -9.298  -2.496  1   31.796  ? 306  ILE A HD13 1 c 
ATOM   4570  N  N    . LEU A 1 301 ? 20.27   -13.087 -3.882  1   27.386  ? 307  LEU A N    1 ? 
ATOM   4571  C  CA   . LEU A 1 301 ? 19.911  -14.495 -3.98   1   27.723  ? 307  LEU A CA   1 ? 
ATOM   4572  C  C    . LEU A 1 301 ? 18.802  -14.695 -5.001  1   30.677  ? 307  LEU A C    1 ? 
ATOM   4573  O  O    . LEU A 1 301 ? 18.862  -15.591 -5.847  1   32.579  ? 307  LEU A O    1 ? 
ATOM   4574  C  CB   . LEU A 1 301 ? 19.531  -15.009 -2.59   1   32.663  ? 307  LEU A CB   1 ? 
ATOM   4575  C  CG   . LEU A 1 301 ? 19.066  -16.462 -2.532  1   32.72   ? 307  LEU A CG   1 ? 
ATOM   4576  C  CD1  . LEU A 1 301 ? 20.193  -17.419 -2.945  1   33.857  ? 307  LEU A CD1  1 ? 
ATOM   4577  C  CD2  . LEU A 1 301 ? 18.541  -16.749 -1.142  1   34.406  ? 307  LEU A CD2  1 ? 
ATOM   4578  H  H    . LEU A 1 301 ? 20.029  -12.618 -3.135  1   27.193  ? 307  LEU A H    1 c 
ATOM   4579  H  HA   . LEU A 1 301 ? 20.709  -14.991 -4.293  1   29.063  ? 307  LEU A HA   1 c 
ATOM   4580  H  HB2  . LEU A 1 301 ? 20.313  -14.909 -2      1   31.476  ? 307  LEU A HB2  1 c 
ATOM   4581  H  HB3  . LEU A 1 301 ? 18.811  -14.437 -2.237  1   31.477  ? 307  LEU A HB3  1 c 
ATOM   4582  H  HG   . LEU A 1 301 ? 18.316  -16.576 -3.171  1   33.215  ? 307  LEU A HG   1 c 
ATOM   4583  H  HD11 . LEU A 1 301 ? 20.409  -17.283 -3.882  1   33.455  ? 307  LEU A HD11 1 c 
ATOM   4584  H  HD12 . LEU A 1 301 ? 19.904  -18.338 -2.81   1   33.504  ? 307  LEU A HD12 1 c 
ATOM   4585  H  HD13 . LEU A 1 301 ? 20.981  -17.246 -2.403  1   33.505  ? 307  LEU A HD13 1 c 
ATOM   4586  H  HD21 . LEU A 1 301 ? 17.805  -16.147 -0.941  1   33.88   ? 307  LEU A HD21 1 c 
ATOM   4587  H  HD22 . LEU A 1 301 ? 19.253  -16.617 -0.492  1   33.893  ? 307  LEU A HD22 1 c 
ATOM   4588  H  HD23 . LEU A 1 301 ? 18.229  -17.668 -1.095  1   33.893  ? 307  LEU A HD23 1 c 
ATOM   4589  N  N    . SER A 1 302 ? 17.805  -13.809 -4.996  1   25.743  ? 308  SER A N    1 ? 
ATOM   4590  C  CA   . SER A 1 302 ? 16.759  -13.9   -5.996  1   27.859  ? 308  SER A CA   1 ? 
ATOM   4591  C  C    . SER A 1 302 ? 17.351  -13.859 -7.411  1   29.921  ? 308  SER A C    1 ? 
ATOM   4592  O  O    . SER A 1 302 ? 17.061  -14.701 -8.241  1   31.495  ? 308  SER A O    1 ? 
ATOM   4593  C  CB   . SER A 1 302 ? 15.708  -12.837 -5.758  1   29.468  ? 308  SER A CB   1 ? 
ATOM   4594  O  OG   . SER A 1 302 ? 14.719  -12.83  -6.777  1   31.634  ? 308  SER A OG   1 ? 
ATOM   4595  H  H    . SER A 1 302 ? 17.769  -13.149 -4.364  1   27.342  ? 308  SER A H    1 c 
ATOM   4596  H  HA   . SER A 1 302 ? 16.321  -14.782 -5.885  1   28.121  ? 308  SER A HA   1 c 
ATOM   4597  H  HB2  . SER A 1 302 ? 15.281  -12.998 -4.895  1   29.592  ? 308  SER A HB2  1 c 
ATOM   4598  H  HB3  . SER A 1 302 ? 16.14   -11.963 -5.722  1   29.592  ? 308  SER A HB3  1 c 
ATOM   4599  H  HG   . SER A 1 302 ? 14.145  -12.251 -6.596  0   31.34   ? 308  SER A HG   1 c 
ATOM   4600  N  N    . ASP A 1 303 ? 18.198  -12.873 -7.706  1   28.871  ? 309  ASP A N    1 ? 
ATOM   4601  C  CA   . ASP A 1 303 ? 18.715  -12.698 -9.049  1   27.029  ? 309  ASP A CA   1 ? 
ATOM   4602  C  C    . ASP A 1 303 ? 19.577  -13.907 -9.413  1   28.728  ? 309  ASP A C    1 ? 
ATOM   4603  O  O    . ASP A 1 303 ? 19.521  -14.377 -10.528 1   34.75   ? 309  ASP A O    1 ? 
ATOM   4604  C  CB   . ASP A 1 303 ? 19.507  -11.399 -9.146  1   32.389  ? 309  ASP A CB   1 ? 
ATOM   4605  C  CG   . ASP A 1 303 ? 18.708  -10.111 -8.966  1   35.253  ? 309  ASP A CG   1 ? 
ATOM   4606  O  OD1  . ASP A 1 303 ? 17.462  -10.177 -8.883  1   34.671  ? 309  ASP A OD1  1 ? 
ATOM   4607  O  OD2  . ASP A 1 303 ? 19.339  -9.041  -8.92   1   39.353  ? 309  ASP A OD2  1 ? 
ATOM   4608  H  H    . ASP A 1 303 ? 18.46   -12.291 -7.051  1   28.717  ? 309  ASP A H    1 c 
ATOM   4609  H  HA   . ASP A 1 303 ? 17.955  -12.651 -9.673  1   28.669  ? 309  ASP A HA   1 c 
ATOM   4610  H  HB2  . ASP A 1 303 ? 20.212  -11.414 -8.465  1   31.683  ? 309  ASP A HB2  1 c 
ATOM   4611  H  HB3  . ASP A 1 303 ? 19.941  -11.364 -10.024 1   31.67   ? 309  ASP A HB3  1 c 
ATOM   4612  N  N    . GLY A 1 304 ? 20.353  -14.411 -8.447  1   27.187  ? 310  GLY A N    1 ? 
ATOM   4613  C  CA   . GLY A 1 304 ? 21.197  -15.572 -8.645  1   32.667  ? 310  GLY A CA   1 ? 
ATOM   4614  C  C    . GLY A 1 304 ? 20.437  -16.895 -8.802  1   35.949  ? 310  GLY A C    1 ? 
ATOM   4615  O  O    . GLY A 1 304 ? 21.074  -17.892 -9.188  1   39.172  ? 310  GLY A O    1 ? 
ATOM   4616  H  H    . GLY A 1 304 ? 20.361  -14.004 -7.629  1   28.71   ? 310  GLY A H    1 c 
ATOM   4617  H  HA2  . GLY A 1 304 ? 21.749  -15.424 -9.448  1   31.929  ? 310  GLY A HA2  1 c 
ATOM   4618  H  HA3  . GLY A 1 304 ? 21.81   -15.646 -7.876  1   31.932  ? 310  GLY A HA3  1 c 
ATOM   4619  N  N    . THR A 1 305 ? 19.118  -16.901 -8.528  1   35.928  ? 311  THR A N    1 ? 
ATOM   4620  C  CA   . THR A 1 305 ? 18.268  -18.084 -8.691  1   33.68   ? 311  THR A CA   1 ? 
ATOM   4621  C  C    . THR A 1 305 ? 17.119  -17.845 -9.656  1   35.425  ? 311  THR A C    1 ? 
ATOM   4622  O  O    . THR A 1 305 ? 16.132  -18.573 -9.596  1   42.133  ? 311  THR A O    1 ? 
ATOM   4623  C  CB   . THR A 1 305 ? 17.674  -18.519 -7.356  1   34.487  ? 311  THR A CB   1 ? 
ATOM   4624  O  OG1  . THR A 1 305 ? 17.019  -17.408 -6.726  1   32.842  ? 311  THR A OG1  1 ? 
ATOM   4625  C  CG2  . THR A 1 305 ? 18.729  -19.089 -6.424  1   33.733  ? 311  THR A CG2  1 ? 
ATOM   4626  H  H    . THR A 1 305 ? 18.732  -16.137 -8.209  1   35.247  ? 311  THR A H    1 c 
ATOM   4627  H  HA   . THR A 1 305 ? 18.819  -18.817 -9.037  1   34.63   ? 311  THR A HA   1 c 
ATOM   4628  H  HB   . THR A 1 305 ? 17.009  -19.231 -7.513  1   33.93   ? 311  THR A HB   1 c 
ATOM   4629  H  HG1  . THR A 1 305 ? 17.596  -16.772 -6.586  0   32.54   ? 311  THR A HG1  1 c 
ATOM   4630  H  HG21 . THR A 1 305 ? 18.329  -19.291 -5.563  1   34.005  ? 311  THR A HG21 1 c 
ATOM   4631  H  HG22 . THR A 1 305 ? 19.441  -18.437 -6.303  1   33.976  ? 311  THR A HG22 1 c 
ATOM   4632  H  HG23 . THR A 1 305 ? 19.098  -19.902 -6.809  1   33.968  ? 311  THR A HG23 1 c 
ATOM   4633  N  N    . ASP A 1 306 ? 17.233  -16.856 -10.545 1   41.574  ? 312  ASP A N    1 ? 
ATOM   4634  C  CA   . ASP A 1 306 ? 16.156  -16.476 -11.464 1   46.179  ? 312  ASP A CA   1 ? 
ATOM   4635  C  C    . ASP A 1 306 ? 14.835  -16.253 -10.74  1   41.451  ? 312  ASP A C    1 ? 
ATOM   4636  O  O    . ASP A 1 306 ? 13.797  -16.529 -11.31  1   42.317  ? 312  ASP A O    1 ? 
ATOM   4637  C  CB   . ASP A 1 306 ? 15.879  -17.522 -12.541 1   47.563  ? 312  ASP A CB   1 ? 
ATOM   4638  C  CG   . ASP A 1 306 ? 16.691  -17.356 -13.807 1   55.412  ? 312  ASP A CG   1 ? 
ATOM   4639  O  OD1  . ASP A 1 306 ? 17.255  -16.255 -13.987 1   52.914  ? 312  ASP A OD1  1 ? 
ATOM   4640  O  OD2  . ASP A 1 306 ? 16.772  -18.335 -14.581 1   69.214  ? 312  ASP A OD2  1 ? 
ATOM   4641  H  H    . ASP A 1 306 ? 18.021  -16.395 -10.592 1   40.876  ? 312  ASP A H    1 c 
ATOM   4642  H  HA   . ASP A 1 306 ? 16.411  -15.633 -11.902 1   44.695  ? 312  ASP A HA   1 c 
ATOM   4643  H  HB2  . ASP A 1 306 ? 16.067  -18.413 -12.181 1   48.824  ? 312  ASP A HB2  1 c 
ATOM   4644  H  HB3  . ASP A 1 306 ? 14.936  -17.502 -12.805 1   48.846  ? 312  ASP A HB3  1 c 
ATOM   4645  N  N    . GLY A 1 307 ? 14.869  -15.755 -9.505  1   39.611  ? 313  GLY A N    1 ? 
ATOM   4646  C  CA   . GLY A 1 307 ? 13.657  -15.529 -8.729  1   38.131  ? 313  GLY A CA   1 ? 
ATOM   4647  C  C    . GLY A 1 307 ? 13.055  -16.806 -8.143  1   40.275  ? 313  GLY A C    1 ? 
ATOM   4648  O  O    . GLY A 1 307 ? 12.035  -16.745 -7.47   1   38.931  ? 313  GLY A O    1 ? 
ATOM   4649  H  H    . GLY A 1 307 ? 15.674  -15.532 -9.134  1   39.67   ? 313  GLY A H    1 c 
ATOM   4650  H  HA2  . GLY A 1 307 ? 13.867  -14.907 -7.995  1   38.912  ? 313  GLY A HA2  1 c 
ATOM   4651  H  HA3  . GLY A 1 307 ? 12.988  -15.091 -9.306  1   38.973  ? 313  GLY A HA3  1 c 
ATOM   4652  N  N    . LYS A 1 308 ? 13.716  -17.95  -8.318  1   37.767  ? 314  LYS A N    1 ? 
ATOM   4653  C  CA   . LYS A 1 308 ? 13.19   -19.194 -7.79   1   41.741  ? 314  LYS A CA   1 ? 
ATOM   4654  C  C    . LYS A 1 308 ? 13.252  -19.203 -6.272  1   37.257  ? 314  LYS A C    1 ? 
ATOM   4655  O  O    . LYS A 1 308 ? 12.373  -19.791 -5.664  1   35.034  ? 314  LYS A O    1 ? 
ATOM   4656  C  CB   . LYS A 1 308 ? 13.852  -20.429 -8.411  1   41.12   ? 314  LYS A CB   1 ? 
ATOM   4657  C  CG   . LYS A 1 308 ? 13.488  -20.547 -9.877  1   40.558  ? 314  LYS A CG   1 ? 
ATOM   4658  C  CD   . LYS A 1 308 ? 14.296  -21.546 -10.697 1   46.134  ? 314  LYS A CD   1 ? 
ATOM   4659  C  CE   . LYS A 1 308 ? 13.853  -21.383 -12.14  1   55.547  ? 314  LYS A CE   1 ? 
ATOM   4660  N  NZ   . LYS A 1 308 ? 14.546  -22.25  -13.095 1   58.856  ? 314  LYS A NZ   1 ? 
ATOM   4661  H  H    . LYS A 1 308 ? 14.513  -17.959 -8.761  1   39.225  ? 314  LYS A H    1 c 
ATOM   4662  H  HA   . LYS A 1 308 ? 12.232  -19.24  -8.044  1   39.944  ? 314  LYS A HA   1 c 
ATOM   4663  H  HB2  . LYS A 1 308 ? 14.826  -20.364 -8.323  1   41.13   ? 314  LYS A HB2  1 c 
ATOM   4664  H  HB3  . LYS A 1 308 ? 13.552  -21.236 -7.94   1   41.108  ? 314  LYS A HB3  1 c 
ATOM   4665  H  HG2  . LYS A 1 308 ? 12.539  -20.791 -9.936  1   41.92   ? 314  LYS A HG2  1 c 
ATOM   4666  H  HG3  . LYS A 1 308 ? 13.584  -19.659 -10.286 1   42.013  ? 314  LYS A HG3  1 c 
ATOM   4667  H  HD2  . LYS A 1 308 ? 15.256  -21.354 -10.62  1   46.753  ? 314  LYS A HD2  1 c 
ATOM   4668  H  HD3  . LYS A 1 308 ? 14.114  -22.463 -10.395 1   46.753  ? 314  LYS A HD3  1 c 
ATOM   4669  H  HE2  . LYS A 1 308 ? 12.898  -21.564 -12.196 1   53.96   ? 314  LYS A HE2  1 c 
ATOM   4670  H  HE3  . LYS A 1 308 ? 13.992  -20.457 -12.41  1   53.82   ? 314  LYS A HE3  1 c 
ATOM   4671  H  HZ1  . LYS A 1 308 ? 14.424  -23.118 -12.865 1   57.817  ? 314  LYS A HZ1  1 c 
ATOM   4672  H  HZ2  . LYS A 1 308 ? 15.432  -22.062 -13.092 1   57.817  ? 314  LYS A HZ2  1 c 
ATOM   4673  H  HZ3  . LYS A 1 308 ? 14.215  -22.114 -13.928 1   57.817  ? 314  LYS A HZ3  1 c 
ATOM   4674  N  N    . VAL A 1 309 ? 14.246  -18.545 -5.66   1   38.39   ? 315  VAL A N    1 ? 
ATOM   4675  C  CA   . VAL A 1 309 ? 14.326  -18.496 -4.202  1   38.063  ? 315  VAL A CA   1 ? 
ATOM   4676  C  C    . VAL A 1 309 ? 14.062  -17.061 -3.747  1   38.273  ? 315  VAL A C    1 ? 
ATOM   4677  O  O    . VAL A 1 309 ? 14.86   -16.183 -4.058  1   42.568  ? 315  VAL A O    1 ? 
ATOM   4678  C  CB   . VAL A 1 309 ? 15.668  -19.03  -3.696  1   36.638  ? 315  VAL A CB   1 ? 
ATOM   4679  C  CG1  . VAL A 1 309 ? 15.672  -19.263 -2.179  1   38.575  ? 315  VAL A CG1  1 ? 
ATOM   4680  C  CG2  . VAL A 1 309 ? 16.039  -20.331 -4.414  1   38.517  ? 315  VAL A CG2  1 ? 
ATOM   4681  H  H    . VAL A 1 309 ? 14.89   -18.126 -6.155  1   38.064  ? 315  VAL A H    1 c 
ATOM   4682  H  HA   . VAL A 1 309 ? 13.621  -19.065 -3.838  1   37.884  ? 315  VAL A HA   1 c 
ATOM   4683  H  HB   . VAL A 1 309 ? 16.354  -18.355 -3.908  1   37.626  ? 315  VAL A HB   1 c 
ATOM   4684  H  HG11 . VAL A 1 309 ? 14.958  -19.88  -1.943  1   37.998  ? 315  VAL A HG11 1 c 
ATOM   4685  H  HG12 . VAL A 1 309 ? 15.533  -18.418 -1.719  1   37.999  ? 315  VAL A HG12 1 c 
ATOM   4686  H  HG13 . VAL A 1 309 ? 16.526  -19.64  -1.91   1   37.998  ? 315  VAL A HG13 1 c 
ATOM   4687  H  HG21 . VAL A 1 309 ? 16.853  -20.695 -4.027  1   37.95   ? 315  VAL A HG21 1 c 
ATOM   4688  H  HG22 . VAL A 1 309 ? 16.182  -20.154 -5.359  1   37.93   ? 315  VAL A HG22 1 c 
ATOM   4689  H  HG23 . VAL A 1 309 ? 15.318  -20.976 -4.312  1   37.95   ? 315  VAL A HG23 1 c 
ATOM   4690  N  N    . SER A 1 310 ? 12.911  -16.834 -3.083  1   38.189  ? 316  SER A N    1 ? 
ATOM   4691  C  CA   . SER A 1 310 ? 12.394  -15.49  -2.814  1   42.083  ? 316  SER A CA   1 ? 
ATOM   4692  C  C    . SER A 1 310 ? 11.534  -15.461 -1.545  1   36.801  ? 316  SER A C    1 ? 
ATOM   4693  O  O    . SER A 1 310 ? 10.69   -16.315 -1.323  1   39.562  ? 316  SER A O    1 ? 
ATOM   4694  C  CB   . SER A 1 310 ? 11.598  -14.947 -3.982  1   42.786  ? 316  SER A CB   1 ? 
ATOM   4695  O  OG   . SER A 1 310 ? 11.262  -13.585 -3.743  1   44.192  ? 316  SER A OG   1 ? 
ATOM   4696  H  H    . SER A 1 310 ? 12.429  -17.55  -2.784  1   39.02   ? 316  SER A H    1 c 
ATOM   4697  H  HA   . SER A 1 310 ? 13.17   -14.892 -2.668  1   40.33   ? 316  SER A HA   1 c 
ATOM   4698  H  HB2  . SER A 1 310 ? 12.127  -15.016 -4.799  1   42.957  ? 316  SER A HB2  1 c 
ATOM   4699  H  HB3  . SER A 1 310 ? 10.782  -15.472 -4.094  1   42.957  ? 316  SER A HB3  1 c 
ATOM   4700  H  HG   . SER A 1 310 ? 10.814  -13.283 -4.387  0   43.13   ? 316  SER A HG   1 c 
ATOM   4701  N  N    . LEU A 1 311 ? 11.728  -14.444 -0.711  1   33.867  ? 317  LEU A N    1 ? 
ATOM   4702  C  CA   . LEU A 1 311 ? 10.889  -14.229 0.452   1   31.79   ? 317  LEU A CA   1 ? 
ATOM   4703  C  C    . LEU A 1 311 ? 10.087  -12.94  0.298   1   36.535  ? 317  LEU A C    1 ? 
ATOM   4704  O  O    . LEU A 1 311 ? 9.498   -12.469 1.283   1   35.836  ? 317  LEU A O    1 ? 
ATOM   4705  C  CB   . LEU A 1 311 ? 11.758  -14.138 1.694   1   32.269  ? 317  LEU A CB   1 ? 
ATOM   4706  C  CG   . LEU A 1 311 ? 12.655  -15.349 1.954   1   34.141  ? 317  LEU A CG   1 ? 
ATOM   4707  C  CD1  . LEU A 1 311 ? 13.322  -15.022 3.281   1   33.56   ? 317  LEU A CD1  1 ? 
ATOM   4708  C  CD2  . LEU A 1 311 ? 11.927  -16.691 1.918   1   27.68   ? 317  LEU A CD2  1 ? 
ATOM   4709  H  H    . LEU A 1 311 ? 12.41   -13.857 -0.872  1   34.152  ? 317  LEU A H    1 c 
ATOM   4710  H  HA   . LEU A 1 311 ? 10.261  -14.989 0.544   1   33.11   ? 317  LEU A HA   1 c 
ATOM   4711  H  HB2  . LEU A 1 311 ? 12.327  -13.339 1.613   1   32.611  ? 317  LEU A HB2  1 c 
ATOM   4712  H  HB3  . LEU A 1 311 ? 11.168  -14.014 2.473   1   32.609  ? 317  LEU A HB3  1 c 
ATOM   4713  H  HG   . LEU A 1 311 ? 13.359  -15.365 1.256   1   32.398  ? 317  LEU A HG   1 c 
ATOM   4714  H  HD11 . LEU A 1 311 ? 13.82   -14.191 3.2     1   33.71   ? 317  LEU A HD11 1 c 
ATOM   4715  H  HD12 . LEU A 1 311 ? 13.931  -15.74  3.523   1   33.722  ? 317  LEU A HD12 1 c 
ATOM   4716  H  HD13 . LEU A 1 311 ? 12.646  -14.927 3.972   1   33.709  ? 317  LEU A HD13 1 c 
ATOM   4717  H  HD21 . LEU A 1 311 ? 11.622  -16.873 1.014   1   29.558  ? 317  LEU A HD21 1 c 
ATOM   4718  H  HD22 . LEU A 1 311 ? 11.161  -16.662 2.517   1   29.471  ? 317  LEU A HD22 1 c 
ATOM   4719  H  HD23 . LEU A 1 311 ? 12.532  -17.397 2.202   1   29.472  ? 317  LEU A HD23 1 c 
ATOM   4720  N  N    . PHE A 1 312 ? 10.012  -12.415 -0.932  1   37.991  ? 318  PHE A N    1 ? 
ATOM   4721  C  CA   . PHE A 1 312 ? 9.54    -11.053 -1.116  1   39.532  ? 318  PHE A CA   1 ? 
ATOM   4722  C  C    . PHE A 1 312 ? 8.019   -10.971 -0.976  1   38.499  ? 318  PHE A C    1 ? 
ATOM   4723  O  O    . PHE A 1 312 ? 7.497   -9.87   -0.786  1   35.377  ? 318  PHE A O    1 ? 
ATOM   4724  C  CB   . PHE A 1 312 ? 10.037  -10.492 -2.445  1   38.309  ? 318  PHE A CB   1 ? 
ATOM   4725  C  CG   . PHE A 1 312 ? 11.508  -10.09  -2.484  1   31.678  ? 318  PHE A CG   1 ? 
ATOM   4726  C  CD1  . PHE A 1 312 ? 12.134  -9.521  -1.389  1   33.398  ? 318  PHE A CD1  1 ? 
ATOM   4727  C  CD2  . PHE A 1 312 ? 12.256  -10.267 -3.652  1   28.297  ? 318  PHE A CD2  1 ? 
ATOM   4728  C  CE1  . PHE A 1 312 ? 13.469  -9.146  -1.46   1   34.796  ? 318  PHE A CE1  1 ? 
ATOM   4729  C  CE2  . PHE A 1 312 ? 13.57   -9.891  -3.711  1   29.943  ? 318  PHE A CE2  1 ? 
ATOM   4730  C  CZ   . PHE A 1 312 ? 14.182  -9.354  -2.607  1   30.427  ? 318  PHE A CZ   1 ? 
ATOM   4731  H  H    . PHE A 1 312 ? 10.241  -12.911 -1.664  1   37.886  ? 318  PHE A H    1 c 
ATOM   4732  H  HA   . PHE A 1 312 ? 9.931   -10.502 -0.39   1   38.705  ? 318  PHE A HA   1 c 
ATOM   4733  H  HB2  . PHE A 1 312 ? 9.878   -11.165 -3.143  1   36.847  ? 318  PHE A HB2  1 c 
ATOM   4734  H  HB3  . PHE A 1 312 ? 9.492   -9.705  -2.669  1   36.925  ? 318  PHE A HB3  1 c 
ATOM   4735  H  HD1  . PHE A 1 312 ? 11.652  -9.383  -0.59   1   33.346  ? 318  PHE A HD1  1 c 
ATOM   4736  H  HD2  . PHE A 1 312 ? 11.845  -10.647 -4.413  1   29.612  ? 318  PHE A HD2  1 c 
ATOM   4737  H  HE1  . PHE A 1 312 ? 13.891  -8.771  -0.704  1   33.299  ? 318  PHE A HE1  1 c 
ATOM   4738  H  HE2  . PHE A 1 312 ? 14.064  -10.031 -4.503  1   29.742  ? 318  PHE A HE2  1 c 
ATOM   4739  H  HZ   . PHE A 1 312 ? 15.088  -9.093  -2.651  1   31.293  ? 318  PHE A HZ   1 c 
ATOM   4740  N  N    . LYS A 1 313 ? 7.314   -12.104 -1.026  1   35.648  ? 319  LYS A N    1 ? 
ATOM   4741  C  CA   . LYS A 1 313 ? 5.878   -12.105 -0.737  1   41.749  ? 319  LYS A CA   1 ? 
ATOM   4742  C  C    . LYS A 1 313 ? 5.553   -12.264 0.759   1   39.369  ? 319  LYS A C    1 ? 
ATOM   4743  O  O    . LYS A 1 313 ? 4.395   -12.275 1.14    1   38.974  ? 319  LYS A O    1 ? 
ATOM   4744  C  CB   . LYS A 1 313 ? 5.181   -13.148 -1.617  1   42.533  ? 319  LYS A CB   1 ? 
ATOM   4745  C  CG   . LYS A 1 313 ? 5.293   -12.782 -3.093  1   51.378  ? 319  LYS A CG   1 ? 
ATOM   4746  C  CD   . LYS A 1 313 ? 4.396   -13.542 -4.062  1   61.891  ? 319  LYS A CD   1 ? 
ATOM   4747  C  CE   . LYS A 1 313 ? 4.108   -12.665 -5.261  1   69.786  ? 319  LYS A CE   1 ? 
ATOM   4748  N  NZ   . LYS A 1 313 ? 3.259   -13.336 -6.25   1   74.685  ? 319  LYS A NZ   1 ? 
ATOM   4749  H  H    . LYS A 1 313 ? 7.72    -12.889 -1.256  1   37.653  ? 319  LYS A H    1 c 
ATOM   4750  H  HA   . LYS A 1 313 ? 5.518   -11.226 -1.019  1   40.271  ? 319  LYS A HA   1 c 
ATOM   4751  H  HB2  . LYS A 1 313 ? 5.587   -14.028 -1.473  1   44.221  ? 319  LYS A HB2  1 c 
ATOM   4752  H  HB3  . LYS A 1 313 ? 4.233   -13.203 -1.372  1   44.196  ? 319  LYS A HB3  1 c 
ATOM   4753  H  HG2  . LYS A 1 313 ? 5.102   -11.822 -3.181  1   51.374  ? 319  LYS A HG2  1 c 
ATOM   4754  H  HG3  . LYS A 1 313 ? 6.226   -12.914 -3.368  1   51.255  ? 319  LYS A HG3  1 c 
ATOM   4755  H  HD2  . LYS A 1 313 ? 4.846   -14.363 -4.357  1   60.989  ? 319  LYS A HD2  1 c 
ATOM   4756  H  HD3  . LYS A 1 313 ? 3.553   -13.779 -3.619  1   60.989  ? 319  LYS A HD3  1 c 
ATOM   4757  H  HE2  . LYS A 1 313 ? 3.663   -11.85  -4.968  1   68.876  ? 319  LYS A HE2  1 c 
ATOM   4758  H  HE3  . LYS A 1 313 ? 4.948   -12.414 -5.686  1   68.988  ? 319  LYS A HE3  1 c 
ATOM   4759  H  HZ1  . LYS A 1 313 ? 2.482   -13.594 -5.862  1   73.142  ? 319  LYS A HZ1  1 c 
ATOM   4760  H  HZ2  . LYS A 1 313 ? 3.686   -14.066 -6.575  1   73.142  ? 319  LYS A HZ2  1 c 
ATOM   4761  H  HZ3  . LYS A 1 313 ? 3.077   -12.769 -6.933  1   73.142  ? 319  LYS A HZ3  1 c 
ATOM   4762  N  N    . GLU A 1 314 ? 6.57    -12.38  1.617   1   39.849  ? 320  GLU A N    1 ? 
ATOM   4763  C  CA   . GLU A 1 314 ? 6.38    -12.633 3.028   1   39.01   ? 320  GLU A CA   1 ? 
ATOM   4764  C  C    . GLU A 1 314 ? 6.114   -11.318 3.759   1   46.832  ? 320  GLU A C    1 ? 
ATOM   4765  O  O    . GLU A 1 314 ? 6.968   -10.43  3.728   1   41.272  ? 320  GLU A O    1 ? 
ATOM   4766  C  CB   . GLU A 1 314 ? 7.599   -13.302 3.647   1   39.126  ? 320  GLU A CB   1 ? 
ATOM   4767  C  CG   . GLU A 1 314 ? 7.694   -14.779 3.301   1   48.628  ? 320  GLU A CG   1 ? 
ATOM   4768  C  CD   . GLU A 1 314 ? 6.686   -15.63  4.073   1   53.242  ? 320  GLU A CD   1 ? 
ATOM   4769  O  OE1  . GLU A 1 314 ? 6.592   -16.796 3.659   1   49.673  ? 320  GLU A OE1  1 ? 
ATOM   4770  O  OE2  . GLU A 1 314 ? 6.035   -15.157 5.065   1   54.081  ? 320  GLU A OE2  1 ? 
ATOM   4771  H  H    . GLU A 1 314 ? 7.425   -12.297 1.304   1   39.512  ? 320  GLU A H    1 c 
ATOM   4772  H  HA   . GLU A 1 314 ? 5.602   -13.233 3.137   1   40.589  ? 320  GLU A HA   1 c 
ATOM   4773  H  HB2  . GLU A 1 314 ? 8.406   -12.842 3.34    1   41.068  ? 320  GLU A HB2  1 c 
ATOM   4774  H  HB3  . GLU A 1 314 ? 7.555   -13.203 4.621   1   41.234  ? 320  GLU A HB3  1 c 
ATOM   4775  H  HG2  . GLU A 1 314 ? 7.536   -14.897 2.339   1   47.236  ? 320  GLU A HG2  1 c 
ATOM   4776  H  HG3  . GLU A 1 314 ? 8.599   -15.102 3.501   1   47.236  ? 320  GLU A HG3  1 c 
ATOM   4777  N  N    . PRO A 1 315 ? 4.93    -11.168 4.421   1   44.677  ? 321  PRO A N    1 ? 
ATOM   4778  C  CA   . PRO A 1 315 ? 4.571   -9.94   5.135   1   38.089  ? 321  PRO A CA   1 ? 
ATOM   4779  C  C    . PRO A 1 315 ? 5.649   -9.421  6.073   1   37.295  ? 321  PRO A C    1 ? 
ATOM   4780  O  O    . PRO A 1 315 ? 5.852   -8.217  6.162   1   40.25   ? 321  PRO A O    1 ? 
ATOM   4781  C  CB   . PRO A 1 315 ? 3.283   -10.378 5.921   1   41.322  ? 321  PRO A CB   1 ? 
ATOM   4782  C  CG   . PRO A 1 315 ? 2.636   -11.435 5.046   1   40.57   ? 321  PRO A CG   1 ? 
ATOM   4783  C  CD   . PRO A 1 315 ? 3.827   -12.155 4.429   1   41.595  ? 321  PRO A CD   1 ? 
ATOM   4784  H  HA   . PRO A 1 315 ? 4.334   -9.241  4.475   1   39.706  ? 321  PRO A HA   1 c 
ATOM   4785  H  HB2  . PRO A 1 315 ? 3.52    -10.751 6.802   1   40.453  ? 321  PRO A HB2  1 c 
ATOM   4786  H  HB3  . PRO A 1 315 ? 2.676   -9.613  6.053   1   40.433  ? 321  PRO A HB3  1 c 
ATOM   4787  H  HG2  . PRO A 1 315 ? 2.09    -12.05  5.579   1   40.968  ? 321  PRO A HG2  1 c 
ATOM   4788  H  HG3  . PRO A 1 315 ? 2.076   -11.026 4.354   1   40.968  ? 321  PRO A HG3  1 c 
ATOM   4789  H  HD2  . PRO A 1 315 ? 4.068   -12.944 4.962   1   42.023  ? 321  PRO A HD2  1 c 
ATOM   4790  H  HD3  . PRO A 1 315 ? 3.613   -12.448 3.517   1   42.004  ? 321  PRO A HD3  1 c 
ATOM   4791  N  N    . MET A 1 316 ? 6.297   -10.325 6.817   1   38.678  ? 322  MET A N    1 ? 
ATOM   4792  C  CA   . MET A 1 316 ? 7.31    -9.925  7.766   1   37.709  ? 322  MET A CA   1 ? 
ATOM   4793  C  C    . MET A 1 316 ? 8.468   -9.189  7.066   1   38.123  ? 322  MET A C    1 ? 
ATOM   4794  O  O    . MET A 1 316 ? 9.036   -8.257  7.639   1   39.424  ? 322  MET A O    1 ? 
ATOM   4795  C  CB   . MET A 1 316 ? 7.866   -11.119 8.543   1   37.626  ? 322  MET A CB   1 ? 
ATOM   4796  C  CG   . MET A 1 316 ? 8.947   -10.71  9.505   1   41.217  ? 322  MET A CG   1 ? 
ATOM   4797  S  SD   . MET A 1 316 ? 9.679   -12.146 10.292  1   46.562  ? 322  MET A SD   1 ? 
ATOM   4798  C  CE   . MET A 1 316 ? 11.413  -11.721 10.446  1   63.655  ? 322  MET A CE   1 ? 
ATOM   4799  H  H    . MET A 1 316 ? 6.096   -11.213 6.731   1   38.16   ? 322  MET A H    1 c 
ATOM   4800  H  HA   . MET A 1 316 ? 6.891   -9.295  8.405   1   37.964  ? 322  MET A HA   1 c 
ATOM   4801  H  HB2  . MET A 1 316 ? 7.135   -11.546 9.039   1   38.443  ? 322  MET A HB2  1 c 
ATOM   4802  H  HB3  . MET A 1 316 ? 8.226   -11.774 7.908   1   38.443  ? 322  MET A HB3  1 c 
ATOM   4803  H  HG2  . MET A 1 316 ? 9.646   -10.221 9.031   1   41.245  ? 322  MET A HG2  1 c 
ATOM   4804  H  HG3  . MET A 1 316 ? 8.573   -10.123 10.192  1   41.265  ? 322  MET A HG3  1 c 
ATOM   4805  H  HE1  . MET A 1 316 ? 11.838  -12.326 11.085  1   58.585  ? 322  MET A HE1  1 c 
ATOM   4806  H  HE2  . MET A 1 316 ? 11.849  -11.804 9.574   1   58.765  ? 322  MET A HE2  1 c 
ATOM   4807  H  HE3  . MET A 1 316 ? 11.49   -10.798 10.762  1   58.714  ? 322  MET A HE3  1 c 
ATOM   4808  N  N    . ILE A 1 317 ? 8.805   -9.577  5.838   1   32.922  ? 323  ILE A N    1 ? 
ATOM   4809  C  CA   . ILE A 1 317 ? 9.89    -8.919  5.114   1   34.402  ? 323  ILE A CA   1 ? 
ATOM   4810  C  C    . ILE A 1 317 ? 9.42    -7.521  4.711   1   34.213  ? 323  ILE A C    1 ? 
ATOM   4811  O  O    . ILE A 1 317 ? 10.195  -6.561  4.695   1   41.203  ? 323  ILE A O    1 ? 
ATOM   4812  C  CB   . ILE A 1 317 ? 10.367  -9.787  3.926   1   32.842  ? 323  ILE A CB   1 ? 
ATOM   4813  C  CG1  . ILE A 1 317 ? 10.794  -11.191 4.372   1   35.725  ? 323  ILE A CG1  1 ? 
ATOM   4814  C  CG2  . ILE A 1 317 ? 11.48   -9.125  3.11    1   32.766  ? 323  ILE A CG2  1 ? 
ATOM   4815  C  CD1  . ILE A 1 317 ? 11.923  -11.234 5.393   1   36.259  ? 323  ILE A CD1  1 ? 
ATOM   4816  H  H    . ILE A 1 317 ? 8.354   -10.263 5.436   1   34.497  ? 323  ILE A H    1 c 
ATOM   4817  H  HA   . ILE A 1 317 ? 10.642  -8.817  5.728   1   33.862  ? 323  ILE A HA   1 c 
ATOM   4818  H  HB   . ILE A 1 317 ? 9.601   -9.9    3.33    1   33.671  ? 323  ILE A HB   1 c 
ATOM   4819  H  HG12 . ILE A 1 317 ? 10.016  -11.648 4.75    1   35.148  ? 323  ILE A HG12 1 c 
ATOM   4820  H  HG13 . ILE A 1 317 ? 11.074  -11.694 3.58    1   35.149  ? 323  ILE A HG13 1 c 
ATOM   4821  H  HG21 . ILE A 1 317 ? 11.818  -9.753  2.449   1   32.823  ? 323  ILE A HG21 1 c 
ATOM   4822  H  HG22 . ILE A 1 317 ? 12.204  -8.859  3.701   1   32.868  ? 323  ILE A HG22 1 c 
ATOM   4823  H  HG23 . ILE A 1 317 ? 11.13   -8.34   2.656   1   32.817  ? 323  ILE A HG23 1 c 
ATOM   4824  H  HD11 . ILE A 1 317 ? 12.694  -10.74  5.055   1   36.086  ? 323  ILE A HD11 1 c 
ATOM   4825  H  HD12 . ILE A 1 317 ? 12.18   -12.162 5.55    1   36.093  ? 323  ILE A HD12 1 c 
ATOM   4826  H  HD13 . ILE A 1 317 ? 11.627  -10.835 6.233   1   36.074  ? 323  ILE A HD13 1 c 
ATOM   4827  N  N    . ARG A 1 318 ? 8.138   -7.4    4.389   1   29.325  ? 324  ARG A N    1 ? 
ATOM   4828  C  CA   . ARG A 1 318 ? 7.581   -6.117  4.014   1   36.712  ? 324  ARG A CA   1 ? 
ATOM   4829  C  C    . ARG A 1 318 ? 7.54    -5.177  5.219   1   35.528  ? 324  ARG A C    1 ? 
ATOM   4830  O  O    . ARG A 1 318 ? 7.888   -3.998  5.121   1   37.689  ? 324  ARG A O    1 ? 
ATOM   4831  C  CB   . ARG A 1 318 ? 6.204   -6.268  3.359   1   35.413  ? 324  ARG A CB   1 ? 
ATOM   4832  C  CG   . ARG A 1 318 ? 5.556   -4.912  3.152   1   36.344  ? 324  ARG A CG   1 ? 
ATOM   4833  C  CD   . ARG A 1 318 ? 4.359   -5.047  2.236   1   41.61   ? 324  ARG A CD   1 ? 
ATOM   4834  N  NE   . ARG A 1 318 ? 3.565   -3.815  2.291   1   52.355  ? 324  ARG A NE   1 ? 
ATOM   4835  C  CZ   . ARG A 1 318 ? 2.565   -3.435  1.463   1   61.086  ? 324  ARG A CZ   1 ? 
ATOM   4836  N  NH1  . ARG A 1 318 ? 2.197   -4.183  0.427   1   51.868  ? 324  ARG A NH1  1 ? 
ATOM   4837  N  NH2  . ARG A 1 318 ? 1.954   -2.265  1.668   1   61.255  ? 324  ARG A NH2  1 ? 
ATOM   4838  H  H    . ARG A 1 318 ? 7.595   -8.135  4.389   1   32.076  ? 324  ARG A H    1 c 
ATOM   4839  H  HA   . ARG A 1 318 ? 8.181   -5.713  3.336   1   34.725  ? 324  ARG A HA   1 c 
ATOM   4840  H  HB2  . ARG A 1 318 ? 6.301   -6.717  2.492   1   35.948  ? 324  ARG A HB2  1 c 
ATOM   4841  H  HB3  . ARG A 1 318 ? 5.628   -6.82   3.929   1   35.941  ? 324  ARG A HB3  1 c 
ATOM   4842  H  HG2  . ARG A 1 318 ? 5.262   -4.551  4.016   1   37.343  ? 324  ARG A HG2  1 c 
ATOM   4843  H  HG3  . ARG A 1 318 ? 6.204   -4.293  2.752   1   37.274  ? 324  ARG A HG3  1 c 
ATOM   4844  H  HD2  . ARG A 1 318 ? 4.658   -5.202  1.317   1   42.676  ? 324  ARG A HD2  1 c 
ATOM   4845  H  HD3  . ARG A 1 318 ? 3.806   -5.806  2.515   1   42.586  ? 324  ARG A HD3  1 c 
ATOM   4846  H  HE   . ARG A 1 318 ? 3.749   -3.263  2.934   1   51.225  ? 324  ARG A HE   1 c 
ATOM   4847  H  HH11 . ARG A 1 318 ? 2.549   -4.986  0.313   1   54.365  ? 324  ARG A HH11 1 c 
ATOM   4848  H  HH12 . ARG A 1 318 ? 1.599   -3.879  -0.148  1   54.6    ? 324  ARG A HH12 1 c 
ATOM   4849  H  HH21 . ARG A 1 318 ? 2.212   -1.744  2.334   1   61.004  ? 324  ARG A HH21 1 c 
ATOM   4850  H  HH22 . ARG A 1 318 ? 1.292   -2.011  1.139   1   61.029  ? 324  ARG A HH22 1 c 
ATOM   4851  N  N    . ARG A 1 319 ? 7.129   -5.699  6.364   1   34.99   ? 325  ARG A N    1 ? 
ATOM   4852  C  CA   . ARG A 1 319 ? 7.016   -4.858  7.55    1   39.075  ? 325  ARG A CA   1 ? 
ATOM   4853  C  C    . ARG A 1 319 ? 8.401   -4.385  8.005   1   35.134  ? 325  ARG A C    1 ? 
ATOM   4854  O  O    . ARG A 1 319 ? 8.512   -3.294  8.514   1   29.604  ? 325  ARG A O    1 ? 
ATOM   4855  C  CB   . ARG A 1 319 ? 6.331   -5.573  8.725   1   38.393  ? 325  ARG A CB   1 ? 
ATOM   4856  C  CG   . ARG A 1 319 ? 4.931   -6.12   8.459   1   36.277  ? 325  ARG A CG   1 ? 
ATOM   4857  C  CD   . ARG A 1 319 ? 4.185   -6.445  9.774   1   39.517  ? 325  ARG A CD   1 ? 
ATOM   4858  N  NE   . ARG A 1 319 ? 4.618   -7.744  10.311  1   44.494  ? 325  ARG A NE   1 ? 
ATOM   4859  C  CZ   . ARG A 1 319 ? 4.157   -8.931  9.87    1   45.739  ? 325  ARG A CZ   1 ? 
ATOM   4860  N  NH1  . ARG A 1 319 ? 3.112   -8.999  9.091   1   42.219  ? 325  ARG A NH1  1 ? 
ATOM   4861  N  NH2  . ARG A 1 319 ? 4.714   -10.059 10.23   1   45.667  ? 325  ARG A NH2  1 ? 
ATOM   4862  H  H    . ARG A 1 319 ? 6.908   -6.584  6.419   1   35.968  ? 325  ARG A H    1 c 
ATOM   4863  H  HA   . ARG A 1 319 ? 6.475   -4.062  7.314   1   37.379  ? 325  ARG A HA   1 c 
ATOM   4864  H  HB2  . ARG A 1 319 ? 6.905   -6.318  9.005   1   38.035  ? 325  ARG A HB2  1 c 
ATOM   4865  H  HB3  . ARG A 1 319 ? 6.281   -4.944  9.476   1   38.052  ? 325  ARG A HB3  1 c 
ATOM   4866  H  HG2  . ARG A 1 319 ? 4.414   -5.457  7.952   1   37.47   ? 325  ARG A HG2  1 c 
ATOM   4867  H  HG3  . ARG A 1 319 ? 4.997   -6.935  7.919   1   37.512  ? 325  ARG A HG3  1 c 
ATOM   4868  H  HD2  . ARG A 1 319 ? 4.368   -5.746  10.434  1   39.882  ? 325  ARG A HD2  1 c 
ATOM   4869  H  HD3  . ARG A 1 319 ? 3.221   -6.462  9.613   1   39.948  ? 325  ARG A HD3  1 c 
ATOM   4870  H  HE   . ARG A 1 319 ? 5.207   -7.747  10.953  1   43.611  ? 325  ARG A HE   1 c 
ATOM   4871  H  HH11 . ARG A 1 319 ? 2.842   -8.286  8.632   1   43.227  ? 325  ARG A HH11 1 c 
ATOM   4872  H  HH12 . ARG A 1 319 ? 2.669   -9.771  9.018   1   43.299  ? 325  ARG A HH12 1 c 
ATOM   4873  H  HH21 . ARG A 1 319 ? 5.422   -10.048 10.76   1   45.651  ? 325  ARG A HH21 1 c 
ATOM   4874  H  HH22 . ARG A 1 319 ? 4.387   -10.83  9.946   1   45.632  ? 325  ARG A HH22 1 c 
ATOM   4875  N  N    . MET A 1 320 ? 9.439   -5.23   7.853   1   32.116  ? 326  MET A N    1 ? 
ATOM   4876  C  CA   . MET A 1 320 ? 10.812  -4.888  8.174   1   32.37   ? 326  MET A CA   1 ? 
ATOM   4877  C  C    . MET A 1 320 ? 11.268  -3.702  7.323   1   32.528  ? 326  MET A C    1 ? 
ATOM   4878  O  O    . MET A 1 320 ? 12.1    -2.921  7.754   1   31.411  ? 326  MET A O    1 ? 
ATOM   4879  C  CB   . MET A 1 320 ? 11.748  -6.094  7.972   1   31.663  ? 326  MET A CB   1 ? 
ATOM   4880  C  CG   . MET A 1 320 ? 11.656  -7.124  9.099   1   29.539  ? 326  MET A CG   1 ? 
ATOM   4881  S  SD   . MET A 1 320 ? 12.585  -8.651  8.813   1   37.501  ? 326  MET A SD   1 ? 
ATOM   4882  C  CE   . MET A 1 320 ? 14.226  -8.017  9.226   1   40.344  ? 326  MET A CE   1 ? 
ATOM   4883  H  H    . MET A 1 320 ? 9.27    -6.071  7.537   1   32.9    ? 326  MET A H    1 c 
ATOM   4884  H  HA   . MET A 1 320 ? 10.843  -4.613  9.122   1   32.251  ? 326  MET A HA   1 c 
ATOM   4885  H  HB2  . MET A 1 320 ? 11.525  -6.528  7.121   1   31.335  ? 326  MET A HB2  1 c 
ATOM   4886  H  HB3  . MET A 1 320 ? 12.672  -5.769  7.911   1   31.332  ? 326  MET A HB3  1 c 
ATOM   4887  H  HG2  . MET A 1 320 ? 11.985  -6.716  9.924   1   31.532  ? 326  MET A HG2  1 c 
ATOM   4888  H  HG3  . MET A 1 320 ? 10.718  -7.356  9.24    1   31.494  ? 326  MET A HG3  1 c 
ATOM   4889  H  HE1  . MET A 1 320 ? 14.882  -8.733  9.14    1   39.642  ? 326  MET A HE1  1 c 
ATOM   4890  H  HE2  . MET A 1 320 ? 14.457  -7.29   8.618   1   39.642  ? 326  MET A HE2  1 c 
ATOM   4891  H  HE3  . MET A 1 320 ? 14.225  -7.685  10.143  1   39.708  ? 326  MET A HE3  1 c 
ATOM   4892  N  N    . GLY A 1 321 ? 10.734  -3.564  6.113   1   39.827  ? 327  GLY A N    1 ? 
ATOM   4893  C  CA   . GLY A 1 321 ? 11.04   -2.432  5.254   1   41.389  ? 327  GLY A CA   1 ? 
ATOM   4894  C  C    . GLY A 1 321 ? 10.279  -1.162  5.649   1   33.497  ? 327  GLY A C    1 ? 
ATOM   4895  O  O    . GLY A 1 321 ? 10.84   -0.067  5.656   1   31.562  ? 327  GLY A O    1 ? 
ATOM   4896  H  H    . GLY A 1 321 ? 10.168  -4.209  5.798   1   38.155  ? 327  GLY A H    1 c 
ATOM   4897  H  HA2  . GLY A 1 321 ? 12.01   -2.255  5.289   1   39.032  ? 327  GLY A HA2  1 c 
ATOM   4898  H  HA3  . GLY A 1 321 ? 10.814  -2.67   4.325   1   39.08   ? 327  GLY A HA3  1 c 
ATOM   4899  N  N    . GLU A 1 322 ? 8.983   -1.289  5.883   1   35.44   ? 328  GLU A N    1 ? 
ATOM   4900  C  CA   . GLU A 1 322 ? 8.124   -0.131  6.122   1   38.891  ? 328  GLU A CA   1 ? 
ATOM   4901  C  C    . GLU A 1 322 ? 8.45    0.593   7.432   1   31.817  ? 328  GLU A C    1 ? 
ATOM   4902  O  O    . GLU A 1 322 ? 8.029   1.725   7.624   1   35.417  ? 328  GLU A O    1 ? 
ATOM   4903  C  CB   . GLU A 1 322 ? 6.643   -0.523  6.1     1   35.962  ? 328  GLU A CB   1 ? 
ATOM   4904  C  CG   . GLU A 1 322 ? 6.19    -0.867  4.686   1   41.447  ? 328  GLU A CG   1 ? 
ATOM   4905  C  CD   . GLU A 1 322 ? 4.828   -1.496  4.473   1   37.201  ? 328  GLU A CD   1 ? 
ATOM   4906  O  OE1  . GLU A 1 322 ? 4.361   -1.549  3.314   1   34.066  ? 328  GLU A OE1  1 ? 
ATOM   4907  O  OE2  . GLU A 1 322 ? 4.271   -1.94   5.473   1   33.565  ? 328  GLU A OE2  1 ? 
ATOM   4908  H  H    . GLU A 1 322 ? 8.608   -2.123  5.893   1   35.781  ? 328  GLU A H    1 c 
ATOM   4909  H  HA   . GLU A 1 322 ? 8.27    0.508   5.379   1   36.272  ? 328  GLU A HA   1 c 
ATOM   4910  H  HB2  . GLU A 1 322 ? 6.507   -1.293  6.69    1   37.756  ? 328  GLU A HB2  1 c 
ATOM   4911  H  HB3  . GLU A 1 322 ? 6.108   0.222   6.446   1   37.746  ? 328  GLU A HB3  1 c 
ATOM   4912  H  HG2  . GLU A 1 322 ? 6.22    -0.045  4.152   1   39.075  ? 328  GLU A HG2  1 c 
ATOM   4913  H  HG3  . GLU A 1 322 ? 6.856   -1.47   4.294   1   39.102  ? 328  GLU A HG3  1 c 
ATOM   4914  N  N    . TYR A 1 323 ? 9.149   -0.056  8.354   1   29.075  ? 329  TYR A N    1 ? 
ATOM   4915  C  CA   . TYR A 1 323 ? 9.554   0.555   9.607   1   33.751  ? 329  TYR A CA   1 ? 
ATOM   4916  C  C    . TYR A 1 323 ? 10.273  1.894   9.377   1   32.586  ? 329  TYR A C    1 ? 
ATOM   4917  O  O    . TYR A 1 323 ? 10.141  2.823   10.181  1   29.352  ? 329  TYR A O    1 ? 
ATOM   4918  C  CB   . TYR A 1 323 ? 10.421  -0.435  10.405  1   36.964  ? 329  TYR A CB   1 ? 
ATOM   4919  C  CG   . TYR A 1 323 ? 11.014  0.161   11.672  1   36.876  ? 329  TYR A CG   1 ? 
ATOM   4920  C  CD1  . TYR A 1 323 ? 10.313  0.173   12.879  1   36.688  ? 329  TYR A CD1  1 ? 
ATOM   4921  C  CD2  . TYR A 1 323 ? 12.259  0.782   11.636  1   37.059  ? 329  TYR A CD2  1 ? 
ATOM   4922  C  CE1  . TYR A 1 323 ? 10.869  0.725   14.022  1   37.81   ? 329  TYR A CE1  1 ? 
ATOM   4923  C  CE2  . TYR A 1 323 ? 12.821  1.337   12.766  1   39.202  ? 329  TYR A CE2  1 ? 
ATOM   4924  C  CZ   . TYR A 1 323 ? 12.132  1.289   13.965  1   42.898  ? 329  TYR A CZ   1 ? 
ATOM   4925  O  OH   . TYR A 1 323 ? 12.741  1.86    15.037  1   48.827  ? 329  TYR A OH   1 ? 
ATOM   4926  H  H    . TYR A 1 323 ? 9.373   -0.929  8.207   1   30.863  ? 329  TYR A H    1 c 
ATOM   4927  H  HA   . TYR A 1 323 ? 8.733   0.737   10.135  1   33.123  ? 329  TYR A HA   1 c 
ATOM   4928  H  HB2  . TYR A 1 323 ? 9.869   -1.212  10.645  1   36.193  ? 329  TYR A HB2  1 c 
ATOM   4929  H  HB3  . TYR A 1 323 ? 11.152  -0.748  9.827   1   36.193  ? 329  TYR A HB3  1 c 
ATOM   4930  H  HD1  . TYR A 1 323 ? 9.464   -0.236  12.928  1   37.053  ? 329  TYR A HD1  1 c 
ATOM   4931  H  HD2  . TYR A 1 323 ? 12.747  0.792   10.828  1   37.561  ? 329  TYR A HD2  1 c 
ATOM   4932  H  HE1  . TYR A 1 323 ? 10.398  0.7     14.837  1   38.694  ? 329  TYR A HE1  1 c 
ATOM   4933  H  HE2  . TYR A 1 323 ? 13.679  1.725   12.729  1   39.513  ? 329  TYR A HE2  1 c 
ATOM   4934  H  HH   . TYR A 1 323 ? 13.18   1.3     15.461  0   47.07   ? 329  TYR A HH   1 c 
ATOM   4935  N  N    . ILE A 1 324 ? 11.001  2.032   8.264   1   31.224  ? 330  ILE A N    1 ? 
ATOM   4936  C  CA   . ILE A 1 324 ? 11.782  3.238   8.044   1   28.799  ? 330  ILE A CA   1 ? 
ATOM   4937  C  C    . ILE A 1 324 ? 10.833  4.38    7.654   1   28.557  ? 330  ILE A C    1 ? 
ATOM   4938  O  O    . ILE A 1 324 ? 11.101  5.552   7.906   1   31.433  ? 330  ILE A O    1 ? 
ATOM   4939  C  CB   . ILE A 1 324 ? 12.882  2.984   6.997   1   29.244  ? 330  ILE A CB   1 ? 
ATOM   4940  C  CG1  . ILE A 1 324 ? 13.945  4.102   6.973   1   30.593  ? 330  ILE A CG1  1 ? 
ATOM   4941  C  CG2  . ILE A 1 324 ? 12.263  2.826   5.619   1   31.249  ? 330  ILE A CG2  1 ? 
ATOM   4942  C  CD1  . ILE A 1 324 ? 14.843  4.149   8.19    1   34.373  ? 330  ILE A CD1  1 ? 
ATOM   4943  H  H    . ILE A 1 324 ? 11.033  1.359   7.648   1   30.971  ? 330  ILE A H    1 c 
ATOM   4944  H  HA   . ILE A 1 324 ? 12.215  3.476   8.886   1   29.357  ? 330  ILE A HA   1 c 
ATOM   4945  H  HB   . ILE A 1 324 ? 13.33   2.146   7.228   1   29.772  ? 330  ILE A HB   1 c 
ATOM   4946  H  HG12 . ILE A 1 324 ? 14.504  3.983   6.178   1   31.11   ? 330  ILE A HG12 1 c 
ATOM   4947  H  HG13 . ILE A 1 324 ? 13.49   4.965   6.888   1   31.101  ? 330  ILE A HG13 1 c 
ATOM   4948  H  HG21 . ILE A 1 324 ? 12.913  2.427   5.015   1   30.643  ? 330  ILE A HG21 1 c 
ATOM   4949  H  HG22 . ILE A 1 324 ? 12      3.698   5.277   1   30.635  ? 330  ILE A HG22 1 c 
ATOM   4950  H  HG23 . ILE A 1 324 ? 11.481  2.253   5.673   1   30.653  ? 330  ILE A HG23 1 c 
ATOM   4951  H  HD11 . ILE A 1 324 ? 14.314  4.356   8.984   1   33.182  ? 330  ILE A HD11 1 c 
ATOM   4952  H  HD12 . ILE A 1 324 ? 15.523  4.837   8.066   1   33.204  ? 330  ILE A HD12 1 c 
ATOM   4953  H  HD13 . ILE A 1 324 ? 15.276  3.283   8.306   1   33.215  ? 330  ILE A HD13 1 c 
ATOM   4954  N  N    . SER A 1 325 ? 9.686   4.029   7.074   1   29.395  ? 331  SER A N    1 ? 
ATOM   4955  C  CA   . SER A 1 325 ? 8.639   4.985   6.773   1   27.719  ? 331  SER A CA   1 ? 
ATOM   4956  C  C    . SER A 1 325 ? 7.905   5.432   8.031   1   33.081  ? 331  SER A C    1 ? 
ATOM   4957  O  O    . SER A 1 325 ? 7.592   6.62    8.151   1   37.014  ? 331  SER A O    1 ? 
ATOM   4958  C  CB   . SER A 1 325 ? 7.646   4.392   5.77    1   31.175  ? 331  SER A CB   1 ? 
ATOM   4959  O  OG   . SER A 1 325 ? 6.626   5.351   5.523   1   31.942  ? 331  SER A OG   1 ? 
ATOM   4960  H  H    . SER A 1 325 ? 9.555   3.155   6.84    1   28.873  ? 331  SER A H    1 c 
ATOM   4961  H  HA   . SER A 1 325 ? 9.059   5.782   6.361   1   29.636  ? 331  SER A HA   1 c 
ATOM   4962  H  HB2  . SER A 1 325 ? 8.107   4.176   4.937   1   30.558  ? 331  SER A HB2  1 c 
ATOM   4963  H  HB3  . SER A 1 325 ? 7.253   3.578   6.135   1   30.599  ? 331  SER A HB3  1 c 
ATOM   4964  H  HG   . SER A 1 325 ? 6.066   5.019   4.97    0   32.2    ? 331  SER A HG   1 c 
ATOM   4965  N  N    . ARG A 1 326 ? 7.567   4.472   8.927   1   33.252  ? 332  ARG A N    1 ? 
ATOM   4966  C  CA   . ARG A 1 326 ? 6.73    4.749   10.094  1   33.041  ? 332  ARG A CA   1 ? 
ATOM   4967  C  C    . ARG A 1 326 ? 7.442   5.505   11.21   1   35.529  ? 332  ARG A C    1 ? 
ATOM   4968  O  O    . ARG A 1 326 ? 6.792   6.213   11.996  1   32.279  ? 332  ARG A O    1 ? 
ATOM   4969  C  CB   . ARG A 1 326 ? 6.225   3.469   10.752  1   32.749  ? 332  ARG A CB   1 ? 
ATOM   4970  C  CG   . ARG A 1 326 ? 5.389   2.665   9.77    1   32.055  ? 332  ARG A CG   1 ? 
ATOM   4971  C  CD   . ARG A 1 326 ? 4.186   3.391   9.239   1   31.29   ? 332  ARG A CD   1 ? 
ATOM   4972  N  NE   . ARG A 1 326 ? 3.535   2.623   8.175   1   33.954  ? 332  ARG A NE   1 ? 
ATOM   4973  C  CZ   . ARG A 1 326 ? 2.454   1.86    8.283   1   32.999  ? 332  ARG A CZ   1 ? 
ATOM   4974  N  NH1  . ARG A 1 326 ? 1.888   1.594   9.439   1   34.61   ? 332  ARG A NH1  1 ? 
ATOM   4975  N  NH2  . ARG A 1 326 ? 1.931   1.334   7.208   1   32.654  ? 332  ARG A NH2  1 ? 
ATOM   4976  H  H    . ARG A 1 326 ? 7.877   3.621   8.803   1   33.081  ? 332  ARG A H    1 c 
ATOM   4977  H  HA   . ARG A 1 326 ? 5.958   5.293   9.799   1   33.466  ? 332  ARG A HA   1 c 
ATOM   4978  H  HB2  . ARG A 1 326 ? 6.987   2.929   11.051  1   32.673  ? 332  ARG A HB2  1 c 
ATOM   4979  H  HB3  . ARG A 1 326 ? 5.679   3.694   11.536  1   32.674  ? 332  ARG A HB3  1 c 
ATOM   4980  H  HG2  . ARG A 1 326 ? 5.953   2.398   9.013   1   32.062  ? 332  ARG A HG2  1 c 
ATOM   4981  H  HG3  . ARG A 1 326 ? 5.088   1.842   10.212  1   32.038  ? 332  ARG A HG3  1 c 
ATOM   4982  H  HD2  . ARG A 1 326 ? 3.55    3.543   9.966   1   32.093  ? 332  ARG A HD2  1 c 
ATOM   4983  H  HD3  . ARG A 1 326 ? 4.451   4.262   8.884   1   32.096  ? 332  ARG A HD3  1 c 
ATOM   4984  H  HE   . ARG A 1 326 ? 3.901   2.666   7.388   1   33.105  ? 332  ARG A HE   1 c 
ATOM   4985  H  HH11 . ARG A 1 326 ? 2.39    1.366   10.133  1   34.088  ? 332  ARG A HH11 1 c 
ATOM   4986  H  HH12 . ARG A 1 326 ? 1.006   1.643   9.517   1   34.081  ? 332  ARG A HH12 1 c 
ATOM   4987  H  HH21 . ARG A 1 326 ? 2.34    1.414   6.429   1   32.8    ? 332  ARG A HH21 1 c 
ATOM   4988  H  HH22 . ARG A 1 326 ? 1.165   0.895   7.263   1   32.792  ? 332  ARG A HH22 1 c 
ATOM   4989  N  N    . THR A 1 327 ? 8.769   5.347   11.293  1   38.348  ? 333  THR A N    1 ? 
ATOM   4990  C  CA   . THR A 1 327 ? 9.557   6.08    12.276  1   40.229  ? 333  THR A CA   1 ? 
ATOM   4991  C  C    . THR A 1 327 ? 9.926   7.478   11.799  1   35.761  ? 333  THR A C    1 ? 
ATOM   4992  O  O    . THR A 1 327 ? 10.638  8.151   12.516  1   35.117  ? 333  THR A O    1 ? 
ATOM   4993  C  CB   . THR A 1 327 ? 10.821  5.301   12.635  1   43.598  ? 333  THR A CB   1 ? 
ATOM   4994  O  OG1  . THR A 1 327 ? 11.505  4.963   11.432  1   48.919  ? 333  THR A OG1  1 ? 
ATOM   4995  C  CG2  . THR A 1 327 ? 10.476  4.025   13.374  1   49.911  ? 333  THR A CG2  1 ? 
ATOM   4996  H  H    . THR A 1 327 ? 9.195   4.767   10.73   1   38.024  ? 333  THR A H    1 c 
ATOM   4997  H  HA   . THR A 1 327 ? 9.017   6.168   13.091  1   39.56   ? 333  THR A HA   1 c 
ATOM   4998  H  HB   . THR A 1 327 ? 11.41   5.853   13.203  1   44.942  ? 333  THR A HB   1 c 
ATOM   4999  H  HG1  . THR A 1 327 ? 10.973  4.48    10.903  0   50.01   ? 333  THR A HG1  1 c 
ATOM   5000  H  HG21 . THR A 1 327 ? 11.291  3.616   13.704  1   47.8    ? 333  THR A HG21 1 c 
ATOM   5001  H  HG22 . THR A 1 327 ? 10.024  3.41    12.772  1   47.717  ? 333  THR A HG22 1 c 
ATOM   5002  H  HG23 . THR A 1 327 ? 9.893   4.231   14.123  1   47.762  ? 333  THR A HG23 1 c 
ATOM   5003  N  N    . TYR A 1 328 ? 9.499   7.912   10.611  1   38.594  ? 334  TYR A N    1 ? 
ATOM   5004  C  CA   . TYR A 1 328 ? 9.95    9.196   10.074  1   38.645  ? 334  TYR A CA   1 ? 
ATOM   5005  C  C    . TYR A 1 328 ? 8.877   10.248  10.352  1   36.746  ? 334  TYR A C    1 ? 
ATOM   5006  O  O    . TYR A 1 328 ? 7.801   10.185  9.78    1   40.899  ? 334  TYR A O    1 ? 
ATOM   5007  C  CB   . TYR A 1 328 ? 10.227  9.161   8.566   1   37.817  ? 334  TYR A CB   1 ? 
ATOM   5008  C  CG   . TYR A 1 328 ? 10.861  10.423  7.994   1   37.665  ? 334  TYR A CG   1 ? 
ATOM   5009  C  CD1  . TYR A 1 328 ? 12.232  10.631  8.073   1   35.959  ? 334  TYR A CD1  1 ? 
ATOM   5010  C  CD2  . TYR A 1 328 ? 10.082  11.443  7.421   1   42.685  ? 334  TYR A CD2  1 ? 
ATOM   5011  C  CE1  . TYR A 1 328 ? 12.813  11.787  7.558   1   39.468  ? 334  TYR A CE1  1 ? 
ATOM   5012  C  CE2  . TYR A 1 328 ? 10.65   12.613  6.93    1   38.562  ? 334  TYR A CE2  1 ? 
ATOM   5013  C  CZ   . TYR A 1 328 ? 12.027  12.779  6.988   1   39.023  ? 334  TYR A CZ   1 ? 
ATOM   5014  O  OH   . TYR A 1 328 ? 12.624  13.928  6.554   1   38.709  ? 334  TYR A OH   1 ? 
ATOM   5015  H  H    . TYR A 1 328 ? 8.92    7.406   10.118  1   37.897  ? 334  TYR A H    1 c 
ATOM   5016  H  HA   . TYR A 1 328 ? 10.786  9.462   10.54   1   38.064  ? 334  TYR A HA   1 c 
ATOM   5017  H  HB2  . TYR A 1 328 ? 10.821  8.399   8.38    1   37.968  ? 334  TYR A HB2  1 c 
ATOM   5018  H  HB3  . TYR A 1 328 ? 9.38    8.994   8.098   1   37.968  ? 334  TYR A HB3  1 c 
ATOM   5019  H  HD1  . TYR A 1 328 ? 12.783  9.963   8.448   1   37.239  ? 334  TYR A HD1  1 c 
ATOM   5020  H  HD2  . TYR A 1 328 ? 9.146   11.334  7.374   1   40.436  ? 334  TYR A HD2  1 c 
ATOM   5021  H  HE1  . TYR A 1 328 ? 13.745  11.911  7.622   1   38.531  ? 334  TYR A HE1  1 c 
ATOM   5022  H  HE2  . TYR A 1 328 ? 10.108  13.281  6.547   1   39.553  ? 334  TYR A HE2  1 c 
ATOM   5023  H  HH   . TYR A 1 328 ? 12.874  13.853  5.746   0   38.44   ? 334  TYR A HH   1 c 
ATOM   5024  N  N    . VAL A 1 329 ? 9.169   11.228  11.206  1   35.788  ? 335  VAL A N    1 ? 
ATOM   5025  C  CA   . VAL A 1 329 ? 8.145   12.215  11.554  1   33.466  ? 335  VAL A CA   1 ? 
ATOM   5026  C  C    . VAL A 1 329 ? 7.976   13.314  10.5    1   35.392  ? 335  VAL A C    1 ? 
ATOM   5027  O  O    . VAL A 1 329 ? 6.839   13.659  10.14   1   36.095  ? 335  VAL A O    1 ? 
ATOM   5028  C  CB   . VAL A 1 329 ? 8.435   12.858  12.914  1   31.81   ? 335  VAL A CB   1 ? 
ATOM   5029  C  CG1  . VAL A 1 329 ? 7.403   13.935  13.216  1   32.46   ? 335  VAL A CG1  1 ? 
ATOM   5030  C  CG2  . VAL A 1 329 ? 8.473   11.833  14.035  1   35.077  ? 335  VAL A CG2  1 ? 
ATOM   5031  H  H    . VAL A 1 329 ? 10.002  11.292  11.576  1   35.497  ? 335  VAL A H    1 c 
ATOM   5032  H  HA   . VAL A 1 329 ? 7.293   11.743  11.629  1   34      ? 335  VAL A HA   1 c 
ATOM   5033  H  HB   . VAL A 1 329 ? 9.321   13.286  12.855  1   32.824  ? 335  VAL A HB   1 c 
ATOM   5034  H  HG11 . VAL A 1 329 ? 6.51    13.584  13.057  1   32.286  ? 335  VAL A HG11 1 c 
ATOM   5035  H  HG12 . VAL A 1 329 ? 7.555   14.703  12.641  1   32.325  ? 335  VAL A HG12 1 c 
ATOM   5036  H  HG13 . VAL A 1 329 ? 7.482   14.209  14.145  1   32.305  ? 335  VAL A HG13 1 c 
ATOM   5037  H  HG21 . VAL A 1 329 ? 8.64    12.282  14.881  1   34.069  ? 335  VAL A HG21 1 c 
ATOM   5038  H  HG22 . VAL A 1 329 ? 9.181   11.19   13.865  1   34.085  ? 335  VAL A HG22 1 c 
ATOM   5039  H  HG23 . VAL A 1 329 ? 7.62    11.369  14.08   1   34.078  ? 335  VAL A HG23 1 c 
ATOM   5040  N  N    . GLY A 1 330 ? 9.09    13.964  10.116  1   37.947  ? 336  GLY A N    1 ? 
ATOM   5041  C  CA   . GLY A 1 330 ? 9.076   15.013  9.087   1   35.878  ? 336  GLY A CA   1 ? 
ATOM   5042  C  C    . GLY A 1 330 ? 10.291  15.938  9.206   1   35.595  ? 336  GLY A C    1 ? 
ATOM   5043  O  O    . GLY A 1 330 ? 10.929  15.966  10.256  1   41.202  ? 336  GLY A O    1 ? 
ATOM   5044  H  H    . GLY A 1 330 ? 9.887   13.747  10.508  1   36.817  ? 336  GLY A H    1 c 
ATOM   5045  H  HA2  . GLY A 1 330 ? 9.068   14.591  8.197   1   36.347  ? 336  GLY A HA2  1 c 
ATOM   5046  H  HA3  . GLY A 1 330 ? 8.25    15.545  9.178   1   36.296  ? 336  GLY A HA3  1 c 
ATOM   5047  N  N    . ASN A 1 331 ? 10.683  16.561  8.084   1   42.946  ? 337  ASN A N    1 ? 
ATOM   5048  C  CA   . ASN A 1 331 ? 11.754  17.558  8.001   1   39.568  ? 337  ASN A CA   1 ? 
ATOM   5049  C  C    . ASN A 1 331 ? 12.998  17.091  8.732   1   34.314  ? 337  ASN A C    1 ? 
ATOM   5050  O  O    . ASN A 1 331 ? 13.587  17.852  9.487   1   33.793  ? 337  ASN A O    1 ? 
ATOM   5051  C  CB   . ASN A 1 331 ? 11.338  18.924  8.531   1   49.679  ? 337  ASN A CB   1 ? 
ATOM   5052  C  CG   . ASN A 1 331 ? 10.209  19.471  7.697   1   66.37   ? 337  ASN A CG   1 ? 
ATOM   5053  O  OD1  . ASN A 1 331 ? 10.37   19.636  6.477   1   86.915  ? 337  ASN A OD1  1 ? 
ATOM   5054  N  ND2  . ASN A 1 331 ? 9.052   19.689  8.309   1   67.548  ? 337  ASN A ND2  1 ? 
ATOM   5055  H  H    . ASN A 1 331 ? 10.247  16.348  7.31    1   40.247  ? 337  ASN A H    1 c 
ATOM   5056  H  HA   . ASN A 1 331 ? 11.986  17.671  7.052   1   41.126  ? 337  ASN A HA   1 c 
ATOM   5057  H  HB2  . ASN A 1 331 ? 11.053  18.843  9.463   1   50.591  ? 337  ASN A HB2  1 c 
ATOM   5058  H  HB3  . ASN A 1 331 ? 12.098  19.539  8.491   1   50.26   ? 337  ASN A HB3  1 c 
ATOM   5059  H  HD21 . ASN A 1 331 ? 8.338   19.913  7.832   1   67.195  ? 337  ASN A HD21 1 c 
ATOM   5060  H  HD22 . ASN A 1 331 ? 8.989   19.613  9.191   1   66.702  ? 337  ASN A HD22 1 c 
ATOM   5061  N  N    . GLY A 1 332 ? 13.376  15.831  8.511   1   34.494  ? 338  GLY A N    1 ? 
ATOM   5062  C  CA   . GLY A 1 332 ? 14.58   15.274  9.096   1   33.316  ? 338  GLY A CA   1 ? 
ATOM   5063  C  C    . GLY A 1 332 ? 14.414  14.728  10.515  1   35.934  ? 338  GLY A C    1 ? 
ATOM   5064  O  O    . GLY A 1 332 ? 15.397  14.221  11.084  1   43.921  ? 338  GLY A O    1 ? 
ATOM   5065  H  H    . GLY A 1 332 ? 12.867  15.299  7.97    1   34.299  ? 338  GLY A H    1 c 
ATOM   5066  H  HA2  . GLY A 1 332 ? 14.899  14.546  8.512   1   34.166  ? 338  GLY A HA2  1 c 
ATOM   5067  H  HA3  . GLY A 1 332 ? 15.278  15.971  9.102   1   34.165  ? 338  GLY A HA3  1 c 
ATOM   5068  N  N    . TRP A 1 333 ? 13.248  14.882  11.16   1   36.243  ? 339  TRP A N    1 ? 
ATOM   5069  C  CA   . TRP A 1 333 ? 13.121  14.304  12.504  1   34.175  ? 339  TRP A CA   1 ? 
ATOM   5070  C  C    . TRP A 1 333 ? 12.616  12.867  12.427  1   33.727  ? 339  TRP A C    1 ? 
ATOM   5071  O  O    . TRP A 1 333 ? 11.658  12.566  11.699  1   32.713  ? 339  TRP A O    1 ? 
ATOM   5072  C  CB   . TRP A 1 333 ? 12.191  15.127  13.396  1   35.242  ? 339  TRP A CB   1 ? 
ATOM   5073  C  CG   . TRP A 1 333 ? 12.631  16.549  13.544  1   33.118  ? 339  TRP A CG   1 ? 
ATOM   5074  C  CD1  . TRP A 1 333 ? 12.123  17.647  12.926  1   31.377  ? 339  TRP A CD1  1 ? 
ATOM   5075  C  CD2  . TRP A 1 333 ? 13.654  17.016  14.437  1   32.196  ? 339  TRP A CD2  1 ? 
ATOM   5076  N  NE1  . TRP A 1 333 ? 12.784  18.761  13.35   1   28.694  ? 339  TRP A NE1  1 ? 
ATOM   5077  C  CE2  . TRP A 1 333 ? 13.724  18.405  14.27   1   31.257  ? 339  TRP A CE2  1 ? 
ATOM   5078  C  CE3  . TRP A 1 333 ? 14.495  16.391  15.358  1   32.484  ? 339  TRP A CE3  1 ? 
ATOM   5079  C  CZ2  . TRP A 1 333 ? 14.607  19.185  14.995  1   35.763  ? 339  TRP A CZ2  1 ? 
ATOM   5080  C  CZ3  . TRP A 1 333 ? 15.349  17.171  16.092  1   39.343  ? 339  TRP A CZ3  1 ? 
ATOM   5081  C  CH2  . TRP A 1 333 ? 15.393  18.546  15.918  1   35.236  ? 339  TRP A CH2  1 ? 
ATOM   5082  H  H    . TRP A 1 333 ? 12.545  15.33   10.786  1   35.684  ? 339  TRP A H    1 c 
ATOM   5083  H  HA   . TRP A 1 333 ? 14.021  14.3    12.927  1   34.789  ? 339  TRP A HA   1 c 
ATOM   5084  H  HB2  . TRP A 1 333 ? 11.29   15.11   13.009  1   34.497  ? 339  TRP A HB2  1 c 
ATOM   5085  H  HB3  . TRP A 1 333 ? 12.157  14.709  14.283  1   34.497  ? 339  TRP A HB3  1 c 
ATOM   5086  H  HD1  . TRP A 1 333 ? 11.445  17.645  12.271  1   31.264  ? 339  TRP A HD1  1 c 
ATOM   5087  H  HE1  . TRP A 1 333 ? 12.633  19.573  13.069  1   29.978  ? 339  TRP A HE1  1 c 
ATOM   5088  H  HE3  . TRP A 1 333 ? 14.458  15.459  15.488  1   33.916  ? 339  TRP A HE3  1 c 
ATOM   5089  H  HZ2  . TRP A 1 333 ? 14.63   20.121  14.894  1   34.531  ? 339  TRP A HZ2  1 c 
ATOM   5090  H  HZ3  . TRP A 1 333 ? 15.934  16.764  16.71   1   36.567  ? 339  TRP A HZ3  1 c 
ATOM   5091  H  HH2  . TRP A 1 333 ? 16.014  19.05   16.414  1   36.183  ? 339  TRP A HH2  1 c 
ATOM   5092  N  N    . VAL A 1 334 ? 13.28   11.989  13.197  1   37.755  ? 340  VAL A N    1 ? 
ATOM   5093  C  CA   . VAL A 1 334 ? 12.854  10.602  13.343  1   33.577  ? 340  VAL A CA   1 ? 
ATOM   5094  C  C    . VAL A 1 334 ? 12.688  10.261  14.831  1   32.66   ? 340  VAL A C    1 ? 
ATOM   5095  O  O    . VAL A 1 334 ? 13.374  10.82   15.695  1   33.297  ? 340  VAL A O    1 ? 
ATOM   5096  C  CB   . VAL A 1 334 ? 13.832  9.654   12.617  1   36.439  ? 340  VAL A CB   1 ? 
ATOM   5097  C  CG1  . VAL A 1 334 ? 14.011  10.064  11.155  1   44.728  ? 340  VAL A CG1  1 ? 
ATOM   5098  C  CG2  . VAL A 1 334 ? 15.209  9.595   13.253  1   37.744  ? 340  VAL A CG2  1 ? 
ATOM   5099  H  H    . VAL A 1 334 ? 14.025  12.266  13.648  1   35.786  ? 340  VAL A H    1 c 
ATOM   5100  H  HA   . VAL A 1 334 ? 11.98   10.51   12.918  1   34.648  ? 340  VAL A HA   1 c 
ATOM   5101  H  HB   . VAL A 1 334 ? 13.44   8.75    12.64   1   37.531  ? 340  VAL A HB   1 c 
ATOM   5102  H  HG11 . VAL A 1 334 ? 14.473  10.918  11.11   1   42.062  ? 340  VAL A HG11 1 c 
ATOM   5103  H  HG12 . VAL A 1 334 ? 13.14   10.144  10.732  1   42.027  ? 340  VAL A HG12 1 c 
ATOM   5104  H  HG13 . VAL A 1 334 ? 14.535  9.39    10.69   1   42.055  ? 340  VAL A HG13 1 c 
ATOM   5105  H  HG21 . VAL A 1 334 ? 15.799  9.056   12.699  1   37.414  ? 340  VAL A HG21 1 c 
ATOM   5106  H  HG22 . VAL A 1 334 ? 15.143  9.195   14.136  1   37.342  ? 340  VAL A HG22 1 c 
ATOM   5107  H  HG23 . VAL A 1 334 ? 15.57   10.494  13.331  1   37.355  ? 340  VAL A HG23 1 c 
ATOM   5108  N  N    . VAL A 1 335 ? 11.866  9.241   15.111  1   29.947  ? 341  VAL A N    1 ? 
ATOM   5109  C  CA   . VAL A 1 335 ? 11.715  8.68    16.445  1   30.254  ? 341  VAL A CA   1 ? 
ATOM   5110  C  C    . VAL A 1 335 ? 13.06   8.091   16.873  1   36.045  ? 341  VAL A C    1 ? 
ATOM   5111  O  O    . VAL A 1 335 ? 13.617  7.251   16.15   1   35.109  ? 341  VAL A O    1 ? 
ATOM   5112  C  CB   . VAL A 1 335 ? 10.663  7.545   16.454  1   32.644  ? 341  VAL A CB   1 ? 
ATOM   5113  C  CG1  . VAL A 1 335 ? 10.489  6.967   17.855  1   37.806  ? 341  VAL A CG1  1 ? 
ATOM   5114  C  CG2  . VAL A 1 335 ? 9.318   7.954   15.872  1   32.297  ? 341  VAL A CG2  1 ? 
ATOM   5115  H  H    . VAL A 1 335 ? 11.387  8.87    14.427  1   30.729  ? 341  VAL A H    1 c 
ATOM   5116  H  HA   . VAL A 1 335 ? 11.447  9.384   17.068  1   31.604  ? 341  VAL A HA   1 c 
ATOM   5117  H  HB   . VAL A 1 335 ? 11.017  6.823   15.883  1   33.046  ? 341  VAL A HB   1 c 
ATOM   5118  H  HG11 . VAL A 1 335 ? 10.302  7.686   18.482  1   36.202  ? 341  VAL A HG11 1 c 
ATOM   5119  H  HG12 . VAL A 1 335 ? 11.303  6.508   18.123  1   36.202  ? 341  VAL A HG12 1 c 
ATOM   5120  H  HG13 . VAL A 1 335 ? 9.749   6.337   17.857  1   36.185  ? 341  VAL A HG13 1 c 
ATOM   5121  H  HG21 . VAL A 1 335 ? 8.673   7.24    16.014  1   32.421  ? 341  VAL A HG21 1 c 
ATOM   5122  H  HG22 . VAL A 1 335 ? 9.41    8.12    14.92   1   32.391  ? 341  VAL A HG22 1 c 
ATOM   5123  H  HG23 . VAL A 1 335 ? 9.006   8.762   16.313  1   32.402  ? 341  VAL A HG23 1 c 
ATOM   5124  N  N    . ASN A 1 336 ? 13.525  8.451   18.074  1   30.379  ? 342  ASN A N    1 ? 
ATOM   5125  C  CA   . ASN A 1 336 ? 14.887  8.161   18.495  1   34.671  ? 342  ASN A CA   1 ? 
ATOM   5126  C  C    . ASN A 1 336 ? 14.905  7.641   19.924  1   35.735  ? 342  ASN A C    1 ? 
ATOM   5127  O  O    . ASN A 1 336 ? 15.454  8.27    20.82   1   36.088  ? 342  ASN A O    1 ? 
ATOM   5128  C  CB   . ASN A 1 336 ? 15.808  9.371   18.347  1   32.606  ? 342  ASN A CB   1 ? 
ATOM   5129  C  CG   . ASN A 1 336 ? 15.462  10.503  19.283  1   38.922  ? 342  ASN A CG   1 ? 
ATOM   5130  O  OD1  . ASN A 1 336 ? 14.279  10.829  19.427  1   40.313  ? 342  ASN A OD1  1 ? 
ATOM   5131  N  ND2  . ASN A 1 336 ? 16.463  11.091  19.951  1   40.018  ? 342  ASN A ND2  1 ? 
ATOM   5132  H  H    . ASN A 1 336 ? 12.971  8.89    18.654  1   32.594  ? 342  ASN A H    1 c 
ATOM   5133  H  HA   . ASN A 1 336 ? 15.244  7.453   17.913  1   33.62   ? 342  ASN A HA   1 c 
ATOM   5134  H  HB2  . ASN A 1 336 ? 16.729  9.09    18.514  1   34.514  ? 342  ASN A HB2  1 c 
ATOM   5135  H  HB3  . ASN A 1 336 ? 15.756  9.695   17.427  1   34.469  ? 342  ASN A HB3  1 c 
ATOM   5136  H  HD21 . ASN A 1 336 ? 16.282  11.677  20.592  1   39.646  ? 342  ASN A HD21 1 c 
ATOM   5137  H  HD22 . ASN A 1 336 ? 17.306  10.899  19.752  1   39.579  ? 342  ASN A HD22 1 c 
ATOM   5138  N  N    . PHE A 1 337 ? 14.289  6.478   20.109  1   41.808  ? 343  PHE A N    1 ? 
ATOM   5139  C  CA   . PHE A 1 337 ? 14.408  5.707   21.333  1   45.596  ? 343  PHE A CA   1 ? 
ATOM   5140  C  C    . PHE A 1 337 ? 15.832  5.164   21.378  1   43.966  ? 343  PHE A C    1 ? 
ATOM   5141  O  O    . PHE A 1 337 ? 16.439  4.979   20.331  1   42.065  ? 343  PHE A O    1 ? 
ATOM   5142  C  CB   . PHE A 1 337 ? 13.381  4.554   21.387  1   42.745  ? 343  PHE A CB   1 ? 
ATOM   5143  C  CG   . PHE A 1 337 ? 11.932  5.003   21.439  1   35.411  ? 343  PHE A CG   1 ? 
ATOM   5144  C  CD1  . PHE A 1 337 ? 11.566  6.189   22.056  1   40.723  ? 343  PHE A CD1  1 ? 
ATOM   5145  C  CD2  . PHE A 1 337 ? 10.937  4.245   20.848  1   37.788  ? 343  PHE A CD2  1 ? 
ATOM   5146  C  CE1  . PHE A 1 337 ? 10.236  6.598   22.084  1   40.522  ? 343  PHE A CE1  1 ? 
ATOM   5147  C  CE2  . PHE A 1 337 ? 9.613   4.645   20.903  1   35.096  ? 343  PHE A CE2  1 ? 
ATOM   5148  C  CZ   . PHE A 1 337 ? 9.269   5.822   21.495  1   37.647  ? 343  PHE A CZ   1 ? 
ATOM   5149  H  H    . PHE A 1 337 ? 13.765  6.147   19.436  1   40.961  ? 343  PHE A H    1 c 
ATOM   5150  H  HA   . PHE A 1 337 ? 14.267  6.309   22.109  1   43.77   ? 343  PHE A HA   1 c 
ATOM   5151  H  HB2  . PHE A 1 337 ? 13.509  3.987   20.594  1   41.512  ? 343  PHE A HB2  1 c 
ATOM   5152  H  HB3  . PHE A 1 337 ? 13.571  4.006   22.18   1   41.529  ? 343  PHE A HB3  1 c 
ATOM   5153  H  HD1  . PHE A 1 337 ? 12.227  6.731   22.455  1   39.373  ? 343  PHE A HD1  1 c 
ATOM   5154  H  HD2  . PHE A 1 337 ? 11.162  3.429   20.429  1   36.668  ? 343  PHE A HD2  1 c 
ATOM   5155  H  HE1  . PHE A 1 337 ? 10      7.406   22.51   1   39.797  ? 343  PHE A HE1  1 c 
ATOM   5156  H  HE2  . PHE A 1 337 ? 8.948   4.116   20.492  1   36.362  ? 343  PHE A HE2  1 c 
ATOM   5157  H  HZ   . PHE A 1 337 ? 8.365   6.09    21.525  1   37.657  ? 343  PHE A HZ   1 c 
ATOM   5158  N  N    . ALA A 1 338 ? 16.327  4.91    22.588  1   36.469  ? 344  ALA A N    1 ? 
ATOM   5159  C  CA   . ALA A 1 338 ? 17.639  4.313   22.789  1   40.722  ? 344  ALA A CA   1 ? 
ATOM   5160  C  C    . ALA A 1 338 ? 18.725  5.254   22.251  1   39.954  ? 344  ALA A C    1 ? 
ATOM   5161  O  O    . ALA A 1 338 ? 18.446  6.424   22.007  1   37.488  ? 344  ALA A O    1 ? 
ATOM   5162  C  CB   . ALA A 1 338 ? 17.667  2.939   22.196  1   38.715  ? 344  ALA A CB   1 ? 
ATOM   5163  H  H    . ALA A 1 338 ? 15.826  5.117   23.324  1   39.17   ? 344  ALA A H    1 c 
ATOM   5164  H  HA   . ALA A 1 338 ? 17.78   4.228   23.772  1   39.375  ? 344  ALA A HA   1 c 
ATOM   5165  H  HB1  . ALA A 1 338 ? 16.843  2.471   22.416  1   39.322  ? 344  ALA A HB1  1 c 
ATOM   5166  H  HB2  . ALA A 1 338 ? 17.753  3       21.229  1   39.35   ? 344  ALA A HB2  1 c 
ATOM   5167  H  HB3  . ALA A 1 338 ? 18.421  2.442   22.554  1   39.352  ? 344  ALA A HB3  1 c 
ATOM   5168  N  N    . ASP A 1 339 ? 19.968  4.779   22.128  1   42.29   ? 345  ASP A N    1 ? 
ATOM   5169  C  CA   . ASP A 1 339 ? 21.094  5.684   21.93   1   45.548  ? 345  ASP A CA   1 ? 
ATOM   5170  C  C    . ASP A 1 339 ? 21.209  6.003   20.44   1   41.864  ? 345  ASP A C    1 ? 
ATOM   5171  O  O    . ASP A 1 339 ? 22.109  5.543   19.756  1   43.068  ? 345  ASP A O    1 ? 
ATOM   5172  C  CB   . ASP A 1 339 ? 22.345  5.184   22.639  1   44.723  ? 345  ASP A CB   1 ? 
ATOM   5173  C  CG   . ASP A 1 339 ? 23.356  6.273   22.995  1   49.855  ? 345  ASP A CG   1 ? 
ATOM   5174  O  OD1  . ASP A 1 339 ? 22.969  7.304   23.662  1   45.129  ? 345  ASP A OD1  1 ? 
ATOM   5175  O  OD2  . ASP A 1 339 ? 24.533  6.087   22.596  1   45.845  ? 345  ASP A OD2  1 ? 
ATOM   5176  H  H    . ASP A 1 339 ? 20.123  3.88    22.169  1   42.359  ? 345  ASP A H    1 c 
ATOM   5177  H  HA   . ASP A 1 339 ? 20.876  6.527   22.389  1   44.009  ? 345  ASP A HA   1 c 
ATOM   5178  H  HB2  . ASP A 1 339 ? 22.08   4.732   23.467  1   46.022  ? 345  ASP A HB2  1 c 
ATOM   5179  H  HB3  . ASP A 1 339 ? 22.795  4.529   22.067  1   46.051  ? 345  ASP A HB3  1 c 
ATOM   5180  N  N    . ALA A 1 340 ? 20.259  6.808   19.954  1   40.631  ? 346  ALA A N    1 ? 
ATOM   5181  C  CA   . ALA A 1 340 ? 20.094  7.078   18.544  1   36.81   ? 346  ALA A CA   1 ? 
ATOM   5182  C  C    . ALA A 1 340 ? 19.854  8.569   18.316  1   42.072  ? 346  ALA A C    1 ? 
ATOM   5183  O  O    . ALA A 1 340 ? 19.314  9.302   19.165  1   35.574  ? 346  ALA A O    1 ? 
ATOM   5184  C  CB   . ALA A 1 340 ? 18.946  6.245   18.076  1   39.244  ? 346  ALA A CB   1 ? 
ATOM   5185  H  H    . ALA A 1 340 ? 19.689  7.216   20.541  1   40.088  ? 346  ALA A H    1 c 
ATOM   5186  H  HA   . ALA A 1 340 ? 20.924  6.808   18.062  1   39.024  ? 346  ALA A HA   1 c 
ATOM   5187  H  HB1  . ALA A 1 340 ? 19.144  5.304   18.218  1   38.498  ? 346  ALA A HB1  1 c 
ATOM   5188  H  HB2  . ALA A 1 340 ? 18.145  6.483   18.573  1   38.498  ? 346  ALA A HB2  1 c 
ATOM   5189  H  HB3  . ALA A 1 340 ? 18.793  6.401   17.129  1   38.498  ? 346  ALA A HB3  1 c 
ATOM   5190  N  N    . SER A 1 341 ? 20.265  9.016   17.128  1   44.775  ? 347  SER A N    1 ? 
ATOM   5191  C  CA   . SER A 1 341 ? 20.074  10.384  16.693  1   39.965  ? 347  SER A CA   1 ? 
ATOM   5192  C  C    . SER A 1 341 ? 18.596  10.707  16.493  1   36.199  ? 347  SER A C    1 ? 
ATOM   5193  O  O    . SER A 1 341 ? 17.868  9.964   15.838  1   34.54   ? 347  SER A O    1 ? 
ATOM   5194  C  CB   . SER A 1 341 ? 20.818  10.628  15.409  1   40.612  ? 347  SER A CB   1 ? 
ATOM   5195  O  OG   . SER A 1 341 ? 20.688  12.005  15.088  1   43.608  ? 347  SER A OG   1 ? 
ATOM   5196  H  H    . SER A 1 341 ? 20.682  8.434   16.559  1   42.893  ? 347  SER A H    1 c 
ATOM   5197  H  HA   . SER A 1 341 ? 20.44   10.987  17.39   1   40.172  ? 347  SER A HA   1 c 
ATOM   5198  H  HB2  . SER A 1 341 ? 21.76   10.399  15.522  1   41.156  ? 347  SER A HB2  1 c 
ATOM   5199  H  HB3  . SER A 1 341 ? 20.438  10.081  14.696  1   41.156  ? 347  SER A HB3  1 c 
ATOM   5200  H  HG   . SER A 1 341 ? 21.094  12.115  14.323  0   45.21   ? 347  SER A HG   1 c 
ATOM   5201  N  N    . ALA A 1 342 ? 18.206  11.893  16.939  1   36.41   ? 348  ALA A N    1 ? 
ATOM   5202  C  CA   . ALA A 1 342 ? 16.885  12.428  16.629  1   36.318  ? 348  ALA A CA   1 ? 
ATOM   5203  C  C    . ALA A 1 342 ? 16.73   12.778  15.146  1   39.871  ? 348  ALA A C    1 ? 
ATOM   5204  O  O    . ALA A 1 342 ? 15.595  12.985  14.696  1   40.441  ? 348  ALA A O    1 ? 
ATOM   5205  C  CB   . ALA A 1 342 ? 16.628  13.656  17.483  1   32.17   ? 348  ALA A CB   1 ? 
ATOM   5206  H  H    . ALA A 1 342 ? 18.774  12.392  17.453  1   36.365  ? 348  ALA A H    1 c 
ATOM   5207  H  HA   . ALA A 1 342 ? 16.209  11.735  16.853  1   36.124  ? 348  ALA A HA   1 c 
ATOM   5208  H  HB1  . ALA A 1 342 ? 16.648  13.412  18.423  1   33.371  ? 348  ALA A HB1  1 c 
ATOM   5209  H  HB2  . ALA A 1 342 ? 17.313  14.323  17.31   1   33.412  ? 348  ALA A HB2  1 c 
ATOM   5210  H  HB3  . ALA A 1 342 ? 15.757  14.028  17.267  1   33.416  ? 348  ALA A HB3  1 c 
ATOM   5211  N  N    . LYS A 1 343 ? 17.859  12.912  14.413  1   38.746  ? 349  LYS A N    1 ? 
ATOM   5212  C  CA   . LYS A 1 343 ? 17.858  13.277  12.998  1   40.719  ? 349  LYS A CA   1 ? 
ATOM   5213  C  C    . LYS A 1 343 ? 18.138  12.07   12.092  1   37.263  ? 349  LYS A C    1 ? 
ATOM   5214  O  O    . LYS A 1 343 ? 18.839  11.145  12.461  1   40.231  ? 349  LYS A O    1 ? 
ATOM   5215  C  CB   . LYS A 1 343 ? 18.825  14.457  12.819  1   41.194  ? 349  LYS A CB   1 ? 
ATOM   5216  C  CG   . LYS A 1 343 ? 18.326  15.764  13.441  1   41.681  ? 349  LYS A CG   1 ? 
ATOM   5217  C  CD   . LYS A 1 343 ? 17.167  16.441  12.701  1   49.718  ? 349  LYS A CD   1 ? 
ATOM   5218  C  CE   . LYS A 1 343 ? 17.256  17.952  12.662  1   52.728  ? 349  LYS A CE   1 ? 
ATOM   5219  N  NZ   . LYS A 1 343 ? 16.381  18.539  11.639  1   64.665  ? 349  LYS A NZ   1 ? 
ATOM   5220  H  H    . LYS A 1 343 ? 18.666  12.784  14.822  1   39.398  ? 349  LYS A H    1 c 
ATOM   5221  H  HA   . LYS A 1 343 ? 16.956  13.612  12.778  1   39.83   ? 349  LYS A HA   1 c 
ATOM   5222  H  HB2  . LYS A 1 343 ? 19.688  14.226  13.225  1   41.193  ? 349  LYS A HB2  1 c 
ATOM   5223  H  HB3  . LYS A 1 343 ? 18.975  14.603  11.86   1   41.237  ? 349  LYS A HB3  1 c 
ATOM   5224  H  HG2  . LYS A 1 343 ? 18.044  15.578  14.363  1   43.267  ? 349  LYS A HG2  1 c 
ATOM   5225  H  HG3  . LYS A 1 343 ? 19.081  16.389  13.486  1   43.382  ? 349  LYS A HG3  1 c 
ATOM   5226  H  HD2  . LYS A 1 343 ? 17.142  16.103  11.779  1   48.285  ? 349  LYS A HD2  1 c 
ATOM   5227  H  HD3  . LYS A 1 343 ? 16.324  16.184  13.134  1   48.309  ? 349  LYS A HD3  1 c 
ATOM   5228  H  HE2  . LYS A 1 343 ? 17.004  18.309  13.532  1   54.493  ? 349  LYS A HE2  1 c 
ATOM   5229  H  HE3  . LYS A 1 343 ? 18.174  18.221  12.483  1   54.511  ? 349  LYS A HE3  1 c 
ATOM   5230  H  HZ1  . LYS A 1 343 ? 15.526  18.276  11.78   1   60.722  ? 349  LYS A HZ1  1 c 
ATOM   5231  H  HZ2  . LYS A 1 343 ? 16.646  18.265  10.817  1   60.722  ? 349  LYS A HZ2  1 c 
ATOM   5232  H  HZ3  . LYS A 1 343 ? 16.426  19.443  11.681  1   60.722  ? 349  LYS A HZ3  1 c 
ATOM   5233  N  N    . GLY A 1 344 ? 17.506  12.034  10.912  1   40.498  ? 350  GLY A N    1 ? 
ATOM   5234  C  CA   . GLY A 1 344 ? 17.607  10.895  10.005  1   40.462  ? 350  GLY A CA   1 ? 
ATOM   5235  C  C    . GLY A 1 344 ? 16.977  11.245  8.657   1   48.828  ? 350  GLY A C    1 ? 
ATOM   5236  O  O    . GLY A 1 344 ? 16.65   12.403  8.431   1   53.56   ? 350  GLY A O    1 ? 
ATOM   5237  H  H    . GLY A 1 344 ? 16.992  12.748  10.663  1   39.758  ? 350  GLY A H    1 c 
ATOM   5238  H  HA2  . GLY A 1 344 ? 18.556  10.658  9.879   1   42.189  ? 350  GLY A HA2  1 c 
ATOM   5239  H  HA3  . GLY A 1 344 ? 17.144  10.119  10.4    1   42.197  ? 350  GLY A HA3  1 c 
ATOM   5240  N  N    . GLY A 1 345 ? 16.743  10.244  7.798   1   58.196  ? 351  GLY A N    1 ? 
ATOM   5241  C  CA   . GLY A 1 345 ? 16.227  10.474  6.455   1   54.549  ? 351  GLY A CA   1 ? 
ATOM   5242  C  C    . GLY A 1 345 ? 17.04   9.696   5.421   1   60.835  ? 351  GLY A C    1 ? 
ATOM   5243  O  O    . GLY A 1 345 ? 17.782  10.28   4.632   1   56.331  ? 351  GLY A O    1 ? 
ATOM   5244  H  H    . GLY A 1 345 ? 16.912  9.385   8.061   1   54.887  ? 351  GLY A H    1 c 
ATOM   5245  H  HA2  . GLY A 1 345 ? 15.283  10.19   6.417   1   56.773  ? 351  GLY A HA2  1 c 
ATOM   5246  H  HA3  . GLY A 1 345 ? 16.265  11.436  6.247   1   56.691  ? 351  GLY A HA3  1 c 
ATOM   5247  N  N    . GLY A 1 346 ? 16.796  8.383   5.388   1   64.712  ? 352  GLY A N    1 ? 
ATOM   5248  C  CA   . GLY A 1 346 ? 17.76   7.402   4.929   1   56.792  ? 352  GLY A CA   1 ? 
ATOM   5249  C  C    . GLY A 1 346 ? 18.051  7.415   3.432   1   46.517  ? 352  GLY A C    1 ? 
ATOM   5250  O  O    . GLY A 1 346 ? 18.014  8.44    2.768   1   46.176  ? 352  GLY A O    1 ? 
ATOM   5251  H  H    . GLY A 1 346 ? 15.979  8.086   5.667   1   61.809  ? 352  GLY A H    1 c 
ATOM   5252  H  HA2  . GLY A 1 346 ? 18.605  7.549   5.416   1   55.996  ? 352  GLY A HA2  1 c 
ATOM   5253  H  HA3  . GLY A 1 346 ? 17.43   6.508   5.181   1   55.89   ? 352  GLY A HA3  1 c 
ATOM   5254  N  N    . ASP A 1 347 ? 18.525  6.254   2.961   1   48.16   ? 353  ASP A N    1 ? 
ATOM   5255  C  CA   . ASP A 1 347 ? 19.034  6.079   1.613   1   39.002  ? 353  ASP A CA   1 ? 
ATOM   5256  C  C    . ASP A 1 347 ? 17.828  5.899   0.702   1   33.013  ? 353  ASP A C    1 ? 
ATOM   5257  O  O    . ASP A 1 347 ? 17.339  4.788   0.561   1   34.01   ? 353  ASP A O    1 ? 
ATOM   5258  C  CB   . ASP A 1 347 ? 20.025  4.907   1.593   1   47.532  ? 353  ASP A CB   1 ? 
ATOM   5259  C  CG   . ASP A 1 347 ? 20.676  4.522   0.254   1   43.773  ? 353  ASP A CG   1 ? 
ATOM   5260  O  OD1  . ASP A 1 347 ? 20.238  4.985   -0.799  1   39.842  ? 353  ASP A OD1  1 ? 
ATOM   5261  O  OD2  . ASP A 1 347 ? 21.631  3.72    0.258   1   59.642  ? 353  ASP A OD2  1 ? 
ATOM   5262  H  H    . ASP A 1 347 ? 18.53   5.529   3.518   1   45.68   ? 353  ASP A H    1 c 
ATOM   5263  H  HA   . ASP A 1 347 ? 19.515  6.896   1.35    1   40.857  ? 353  ASP A HA   1 c 
ATOM   5264  H  HB2  . ASP A 1 347 ? 20.748  5.115   2.221   1   44.559  ? 353  ASP A HB2  1 c 
ATOM   5265  H  HB3  . ASP A 1 347 ? 19.562  4.113   1.934   1   44.45   ? 353  ASP A HB3  1 c 
ATOM   5266  N  N    . ALA A 1 348 ? 17.331  6.986   0.099   1   32.716  ? 354  ALA A N    1 ? 
ATOM   5267  C  CA   . ALA A 1 348 ? 16.175  6.893   -0.786  1   31.797  ? 354  ALA A CA   1 ? 
ATOM   5268  C  C    . ALA A 1 348 ? 16.336  5.833   -1.887  1   29.293  ? 354  ALA A C    1 ? 
ATOM   5269  O  O    . ALA A 1 348 ? 15.435  5.017   -2.113  1   29.902  ? 354  ALA A O    1 ? 
ATOM   5270  C  CB   . ALA A 1 348 ? 15.83   8.245   -1.327  1   28.029  ? 354  ALA A CB   1 ? 
ATOM   5271  H  H    . ALA A 1 348 ? 17.719  7.801   0.241   1   32.643  ? 354  ALA A H    1 c 
ATOM   5272  H  HA   . ALA A 1 348 ? 15.409  6.597   -0.22   1   30.753  ? 354  ALA A HA   1 c 
ATOM   5273  H  HB1  . ALA A 1 348 ? 15.53   8.819   -0.602  1   29.115  ? 354  ALA A HB1  1 c 
ATOM   5274  H  HB2  . ALA A 1 348 ? 16.612  8.642   -1.745  1   29.139  ? 354  ALA A HB2  1 c 
ATOM   5275  H  HB3  . ALA A 1 348 ? 15.12   8.163   -1.986  1   29.116  ? 354  ALA A HB3  1 c 
ATOM   5276  N  N    . PRO A 1 349 ? 17.459  5.753   -2.63   1   29.961  ? 355  PRO A N    1 ? 
ATOM   5277  C  CA   . PRO A 1 349 ? 17.576  4.727   -3.674  1   28.642  ? 355  PRO A CA   1 ? 
ATOM   5278  C  C    . PRO A 1 349 ? 17.364  3.294   -3.164  1   34.68   ? 355  PRO A C    1 ? 
ATOM   5279  O  O    . PRO A 1 349 ? 16.653  2.474   -3.788  1   33.57   ? 355  PRO A O    1 ? 
ATOM   5280  C  CB   . PRO A 1 349 ? 18.991  4.942   -4.244  1   30.864  ? 355  PRO A CB   1 ? 
ATOM   5281  C  CG   . PRO A 1 349 ? 19.333  6.447   -3.931  1   29.737  ? 355  PRO A CG   1 ? 
ATOM   5282  C  CD   . PRO A 1 349 ? 18.578  6.721   -2.625  1   32.398  ? 355  PRO A CD   1 ? 
ATOM   5283  H  HA   . PRO A 1 349 ? 16.912  4.923   -4.379  1   30.361  ? 355  PRO A HA   1 c 
ATOM   5284  H  HB2  . PRO A 1 349 ? 19.639  4.339   -3.809  1   30.148  ? 355  PRO A HB2  1 c 
ATOM   5285  H  HB3  . PRO A 1 349 ? 19.008  4.772   -5.213  1   30.11   ? 355  PRO A HB3  1 c 
ATOM   5286  H  HG2  . PRO A 1 349 ? 20.297  6.574   -3.814  1   30.601  ? 355  PRO A HG2  1 c 
ATOM   5287  H  HG3  . PRO A 1 349 ? 19.018  7.036   -4.649  1   30.571  ? 355  PRO A HG3  1 c 
ATOM   5288  H  HD2  . PRO A 1 349 ? 19.16   6.584   -1.848  1   31.278  ? 355  PRO A HD2  1 c 
ATOM   5289  H  HD3  . PRO A 1 349 ? 18.245  7.644   -2.608  1   31.198  ? 355  PRO A HD3  1 c 
ATOM   5290  N  N    . LEU A 1 350 ? 18.018  3.004   -2.042  1   34.073  ? 356  LEU A N    1 ? 
ATOM   5291  C  CA   . LEU A 1 350 ? 17.822  1.767   -1.279  1   36.358  ? 356  LEU A CA   1 ? 
ATOM   5292  C  C    . LEU A 1 350 ? 16.356  1.508   -0.932  1   31.367  ? 356  LEU A C    1 ? 
ATOM   5293  O  O    . LEU A 1 350 ? 15.855  0.402   -1.145  1   31.913  ? 356  LEU A O    1 ? 
ATOM   5294  C  CB   . LEU A 1 350 ? 18.57   1.873   0.05    1   32.342  ? 356  LEU A CB   1 ? 
ATOM   5295  C  CG   . LEU A 1 350 ? 18.328  0.668   0.967   1   31.909  ? 356  LEU A CG   1 ? 
ATOM   5296  C  CD1  . LEU A 1 350 ? 18.823  -0.587  0.237   1   31.438  ? 356  LEU A CD1  1 ? 
ATOM   5297  C  CD2  . LEU A 1 350 ? 19.07   0.85    2.278   1   34.323  ? 356  LEU A CD2  1 ? 
ATOM   5298  H  H    . LEU A 1 350 ? 18.632  3.606   -1.731  1   34.603  ? 356  LEU A H    1 c 
ATOM   5299  H  HA   . LEU A 1 350 ? 18.177  1.008   -1.806  1   34.231  ? 356  LEU A HA   1 c 
ATOM   5300  H  HB2  . LEU A 1 350 ? 19.535  1.937   -0.139  1   33.161  ? 356  LEU A HB2  1 c 
ATOM   5301  H  HB3  . LEU A 1 350 ? 18.279  2.689   0.515   1   33.189  ? 356  LEU A HB3  1 c 
ATOM   5302  H  HG   . LEU A 1 350 ? 17.358  0.583   1.15    1   32.331  ? 356  LEU A HG   1 c 
ATOM   5303  H  HD11 . LEU A 1 350 ? 18.198  -0.824  -0.469  1   31.621  ? 356  LEU A HD11 1 c 
ATOM   5304  H  HD12 . LEU A 1 350 ? 18.89   -1.324  0.868   1   31.589  ? 356  LEU A HD12 1 c 
ATOM   5305  H  HD13 . LEU A 1 350 ? 19.699  -0.415  -0.15   1   31.6    ? 356  LEU A HD13 1 c 
ATOM   5306  H  HD21 . LEU A 1 350 ? 18.753  1.655   2.723   1   33.591  ? 356  LEU A HD21 1 c 
ATOM   5307  H  HD22 . LEU A 1 350 ? 20.023  0.933   2.104   1   33.591  ? 356  LEU A HD22 1 c 
ATOM   5308  H  HD23 . LEU A 1 350 ? 18.912  0.081   2.851   1   33.591  ? 356  LEU A HD23 1 c 
ATOM   5309  N  N    . ILE A 1 351 ? 15.73   2.479   -0.225  1   33.543  ? 357  ILE A N    1 ? 
ATOM   5310  C  CA   . ILE A 1 351 ? 14.355  2.348   0.25    1   32.855  ? 357  ILE A CA   1 ? 
ATOM   5311  C  C    . ILE A 1 351 ? 13.41   2.096   -0.935  1   30.59   ? 357  ILE A C    1 ? 
ATOM   5312  O  O    . ILE A 1 351 ? 12.514  1.261   -0.883  1   25.776  ? 357  ILE A O    1 ? 
ATOM   5313  C  CB   . ILE A 1 351 ? 13.945  3.6     1.064   1   31.542  ? 357  ILE A CB   1 ? 
ATOM   5314  C  CG1  . ILE A 1 351 ? 14.702  3.693   2.344   1   27.295  ? 357  ILE A CG1  1 ? 
ATOM   5315  C  CG2  . ILE A 1 351 ? 12.437  3.66    1.288   1   27.284  ? 357  ILE A CG2  1 ? 
ATOM   5316  C  CD1  . ILE A 1 351 ? 14.744  5.124   2.908   1   30.212  ? 357  ILE A CD1  1 ? 
ATOM   5317  H  H    . ILE A 1 351 ? 16.178  3.256   -0.051  1   32.792  ? 357  ILE A H    1 c 
ATOM   5318  H  HA   . ILE A 1 351 ? 14.313  1.573   0.845   1   32.318  ? 357  ILE A HA   1 c 
ATOM   5319  H  HB   . ILE A 1 351 ? 14.189  4.382   0.529   1   30.091  ? 357  ILE A HB   1 c 
ATOM   5320  H  HG12 . ILE A 1 351 ? 14.283  3.103   3.004   1   28.895  ? 357  ILE A HG12 1 c 
ATOM   5321  H  HG13 . ILE A 1 351 ? 15.618  3.382   2.199   1   28.951  ? 357  ILE A HG13 1 c 
ATOM   5322  H  HG21 . ILE A 1 351 ? 12.224  4.398   1.882   1   28.499  ? 357  ILE A HG21 1 c 
ATOM   5323  H  HG22 . ILE A 1 351 ? 12.135  2.828   1.689   1   28.494  ? 357  ILE A HG22 1 c 
ATOM   5324  H  HG23 . ILE A 1 351 ? 11.984  3.792   0.439   1   28.552  ? 357  ILE A HG23 1 c 
ATOM   5325  H  HD11 . ILE A 1 351 ? 15.149  5.722   2.251   1   29.333  ? 357  ILE A HD11 1 c 
ATOM   5326  H  HD12 . ILE A 1 351 ? 15.275  5.135   3.726   1   29.328  ? 357  ILE A HD12 1 c 
ATOM   5327  H  HD13 . ILE A 1 351 ? 13.838  5.428   3.107   1   29.317  ? 357  ILE A HD13 1 c 
ATOM   5328  N  N    . TYR A 1 352 ? 13.642  2.803   -2.042  1   32.241  ? 358  TYR A N    1 ? 
ATOM   5329  C  CA   . TYR A 1 352 ? 12.931  2.54    -3.279  1   27.997  ? 358  TYR A CA   1 ? 
ATOM   5330  C  C    . TYR A 1 352 ? 13.031  1.076   -3.719  1   29.946  ? 358  TYR A C    1 ? 
ATOM   5331  O  O    . TYR A 1 352 ? 12.006  0.421   -3.971  1   29.286  ? 358  TYR A O    1 ? 
ATOM   5332  C  CB   . TYR A 1 352 ? 13.456  3.406   -4.412  1   29.657  ? 358  TYR A CB   1 ? 
ATOM   5333  C  CG   . TYR A 1 352 ? 12.634  3.09    -5.641  1   31.152  ? 358  TYR A CG   1 ? 
ATOM   5334  C  CD1  . TYR A 1 352 ? 11.38   3.659   -5.807  1   34.469  ? 358  TYR A CD1  1 ? 
ATOM   5335  C  CD2  . TYR A 1 352 ? 13.124  2.247   -6.63   1   34.048  ? 358  TYR A CD2  1 ? 
ATOM   5336  C  CE1  . TYR A 1 352 ? 10.592  3.353   -6.898  1   34.29   ? 358  TYR A CE1  1 ? 
ATOM   5337  C  CE2  . TYR A 1 352 ? 12.346  1.922   -7.721  1   32.222  ? 358  TYR A CE2  1 ? 
ATOM   5338  C  CZ   . TYR A 1 352 ? 11.085  2.483   -7.859  1   38.156  ? 358  TYR A CZ   1 ? 
ATOM   5339  O  OH   . TYR A 1 352 ? 10.311  2.17    -8.943  1   40.033  ? 358  TYR A OH   1 ? 
ATOM   5340  H  H    . TYR A 1 352 ? 14.26   3.476   -2.024  1   30.862  ? 358  TYR A H    1 c 
ATOM   5341  H  HA   . TYR A 1 352 ? 11.972  2.76    -3.137  1   29.472  ? 358  TYR A HA   1 c 
ATOM   5342  H  HB2  . TYR A 1 352 ? 13.356  4.354   -4.175  1   29.665  ? 358  TYR A HB2  1 c 
ATOM   5343  H  HB3  . TYR A 1 352 ? 14.401  3.195   -4.578  1   29.657  ? 358  TYR A HB3  1 c 
ATOM   5344  H  HD1  . TYR A 1 352 ? 11.038  4.231   -5.138  1   33.641  ? 358  TYR A HD1  1 c 
ATOM   5345  H  HD2  . TYR A 1 352 ? 13.971  1.843   -6.524  1   32.967  ? 358  TYR A HD2  1 c 
ATOM   5346  H  HE1  . TYR A 1 352 ? 9.734   3.73    -6.991  1   35.153  ? 358  TYR A HE1  1 c 
ATOM   5347  H  HE2  . TYR A 1 352 ? 12.675  1.335   -8.381  1   33.954  ? 358  TYR A HE2  1 c 
ATOM   5348  H  HH   . TYR A 1 352 ? 10.436  2.741   -9.576  0   39.66   ? 358  TYR A HH   1 c 
ATOM   5349  N  N    . ARG A 1 353 ? 14.246  0.533   -3.784  1   28.104  ? 359  ARG A N    1 ? 
ATOM   5350  C  CA   . ARG A 1 353 ? 14.449  -0.814  -4.325  1   28.274  ? 359  ARG A CA   1 ? 
ATOM   5351  C  C    . ARG A 1 353 ? 13.816  -1.869  -3.404  1   29.779  ? 359  ARG A C    1 ? 
ATOM   5352  O  O    . ARG A 1 353 ? 13.19   -2.831  -3.868  1   31.702  ? 359  ARG A O    1 ? 
ATOM   5353  C  CB   . ARG A 1 353 ? 15.94   -1.117  -4.542  1   28.879  ? 359  ARG A CB   1 ? 
ATOM   5354  C  CG   . ARG A 1 353 ? 16.691  -0.28   -5.595  1   38.169  ? 359  ARG A CG   1 ? 
ATOM   5355  C  CD   . ARG A 1 353 ? 18.234  -0.494  -5.573  1   36.764  ? 359  ARG A CD   1 ? 
ATOM   5356  N  NE   . ARG A 1 353 ? 19.09   0.501   -4.89   1   38.871  ? 359  ARG A NE   1 ? 
ATOM   5357  C  CZ   . ARG A 1 353 ? 19.925  0.194   -3.92   1   46.622  ? 359  ARG A CZ   1 ? 
ATOM   5358  N  NH1  . ARG A 1 353 ? 19.975  -1.025  -3.383  1   69.193  ? 359  ARG A NH1  1 ? 
ATOM   5359  N  NH2  . ARG A 1 353 ? 20.682  1.121   -3.387  1   56.2    ? 359  ARG A NH2  1 ? 
ATOM   5360  H  H    . ARG A 1 353 ? 14.97   1.005   -3.487  1   28.605  ? 359  ARG A H    1 c 
ATOM   5361  H  HA   . ARG A 1 353 ? 13.996  -0.86   -5.205  1   28.63   ? 359  ARG A HA   1 c 
ATOM   5362  H  HB2  . ARG A 1 353 ? 16.397  -1.005  -3.681  1   30.625  ? 359  ARG A HB2  1 c 
ATOM   5363  H  HB3  . ARG A 1 353 ? 16.022  -2.062  -4.791  1   30.611  ? 359  ARG A HB3  1 c 
ATOM   5364  H  HG2  . ARG A 1 353 ? 16.352  -0.513  -6.487  1   35.52   ? 359  ARG A HG2  1 c 
ATOM   5365  H  HG3  . ARG A 1 353 ? 16.499  0.67    -5.446  1   35.512  ? 359  ARG A HG3  1 c 
ATOM   5366  H  HD2  . ARG A 1 353 ? 18.402  -1.376  -5.184  1   37.831  ? 359  ARG A HD2  1 c 
ATOM   5367  H  HD3  . ARG A 1 353 ? 18.513  -0.543  -6.51   1   37.581  ? 359  ARG A HD3  1 c 
ATOM   5368  H  HE   . ARG A 1 353 ? 19.037  1.333   -5.143  1   40.273  ? 359  ARG A HE   1 c 
ATOM   5369  H  HH11 . ARG A 1 353 ? 19.238  -1.385  -3.037  1   60.775  ? 359  ARG A HH11 1 c 
ATOM   5370  H  HH12 . ARG A 1 353 ? 20.75   -1.466  -3.373  1   61.123  ? 359  ARG A HH12 1 c 
ATOM   5371  H  HH21 . ARG A 1 353 ? 20.621  1.959   -3.664  1   52.825  ? 359  ARG A HH21 1 c 
ATOM   5372  H  HH22 . ARG A 1 353 ? 21.255  0.906   -2.748  1   53.108  ? 359  ARG A HH22 1 c 
ATOM   5373  N  N    . TYR A 1 354 ? 13.94   -1.661  -2.082  1   27.702  ? 360  TYR A N    1 ? 
ATOM   5374  C  CA   . TYR A 1 354 ? 13.327  -2.576  -1.137  1   31.364  ? 360  TYR A CA   1 ? 
ATOM   5375  C  C    . TYR A 1 354 ? 11.82   -2.511  -1.371  1   27.783  ? 360  TYR A C    1 ? 
ATOM   5376  O  O    . TYR A 1 354 ? 11.15   -3.525  -1.498  1   28.807  ? 360  TYR A O    1 ? 
ATOM   5377  C  CB   . TYR A 1 354 ? 13.862  -2.228  0.265   1   31.209  ? 360  TYR A CB   1 ? 
ATOM   5378  C  CG   . TYR A 1 354 ? 13.581  -3.177  1.416   1   27.707  ? 360  TYR A CG   1 ? 
ATOM   5379  C  CD1  . TYR A 1 354 ? 12.705  -4.259  1.316   1   30.468  ? 360  TYR A CD1  1 ? 
ATOM   5380  C  CD2  . TYR A 1 354 ? 14.19   -2.968  2.626   1   28.193  ? 360  TYR A CD2  1 ? 
ATOM   5381  C  CE1  . TYR A 1 354 ? 12.405  -5.059  2.407   1   26.305  ? 360  TYR A CE1  1 ? 
ATOM   5382  C  CE2  . TYR A 1 354 ? 13.98   -3.82   3.698   1   30.502  ? 360  TYR A CE2  1 ? 
ATOM   5383  C  CZ   . TYR A 1 354 ? 13.052  -4.837  3.615   1   31.068  ? 360  TYR A CZ   1 ? 
ATOM   5384  O  OH   . TYR A 1 354 ? 12.894  -5.613  4.741   1   30.547  ? 360  TYR A OH   1 ? 
ATOM   5385  H  H    . TYR A 1 354 ? 14.414  -0.945  -1.77   1   28.997  ? 360  TYR A H    1 c 
ATOM   5386  H  HA   . TYR A 1 354 ? 13.633  -3.496  -1.359  1   29.92   ? 360  TYR A HA   1 c 
ATOM   5387  H  HB2  . TYR A 1 354 ? 14.837  -2.121  0.193   1   30.372  ? 360  TYR A HB2  1 c 
ATOM   5388  H  HB3  . TYR A 1 354 ? 13.507  -1.344  0.507   1   30.394  ? 360  TYR A HB3  1 c 
ATOM   5389  H  HD1  . TYR A 1 354 ? 12.234  -4.397  0.512   1   28.833  ? 360  TYR A HD1  1 c 
ATOM   5390  H  HD2  . TYR A 1 354 ? 14.812  -2.264  2.714   1   28.636  ? 360  TYR A HD2  1 c 
ATOM   5391  H  HE1  . TYR A 1 354 ? 11.811  -5.785  2.315   1   28.317  ? 360  TYR A HE1  1 c 
ATOM   5392  H  HE2  . TYR A 1 354 ? 14.402  -3.644  4.522   1   30.04   ? 360  TYR A HE2  1 c 
ATOM   5393  H  HH   . TYR A 1 354 ? 13.455  -6.272  4.727   0   29.2    ? 360  TYR A HH   1 c 
ATOM   5394  N  N    . GLY A 1 355 ? 11.274  -1.298  -1.398  1   34.125  ? 361  GLY A N    1 ? 
ATOM   5395  C  CA   . GLY A 1 355 ? 9.853   -1.111  -1.616  1   32.465  ? 361  GLY A CA   1 ? 
ATOM   5396  C  C    . GLY A 1 355 ? 9.378   -1.751  -2.907  1   33.825  ? 361  GLY A C    1 ? 
ATOM   5397  O  O    . GLY A 1 355 ? 8.37    -2.463  -2.898  1   33.452  ? 361  GLY A O    1 ? 
ATOM   5398  H  H    . GLY A 1 355 ? 11.801  -0.562  -1.27   1   32.09   ? 361  GLY A H    1 c 
ATOM   5399  H  HA2  . GLY A 1 355 ? 9.359   -1.501  -0.856  1   33.158  ? 361  GLY A HA2  1 c 
ATOM   5400  H  HA3  . GLY A 1 355 ? 9.657   -0.145  -1.639  1   33.157  ? 361  GLY A HA3  1 c 
ATOM   5401  N  N    . ARG A 1 356 ? 10.105  -1.554  -4.015  1   30.299  ? 362  ARG A N    1 ? 
ATOM   5402  C  CA   . ARG A 1 356 ? 9.689   -2.204  -5.253  1   34.426  ? 362  ARG A CA   1 ? 
ATOM   5403  C  C    . ARG A 1 356 ? 9.662   -3.739  -5.12   1   37.505  ? 362  ARG A C    1 ? 
ATOM   5404  O  O    . ARG A 1 356 ? 8.715   -4.389  -5.548  1   31.827  ? 362  ARG A O    1 ? 
ATOM   5405  C  CB   . ARG A 1 356 ? 10.593  -1.875  -6.436  1   37.578  ? 362  ARG A CB   1 ? 
ATOM   5406  C  CG   . ARG A 1 356 ? 9.94    -2.391  -7.707  1   40.055  ? 362  ARG A CG   1 ? 
ATOM   5407  C  CD   . ARG A 1 356 ? 10.834  -2.239  -8.912  1   50.299  ? 362  ARG A CD   1 ? 
ATOM   5408  N  NE   . ARG A 1 356 ? 10.443  -0.989  -9.565  1   68.308  ? 362  ARG A NE   1 ? 
ATOM   5409  C  CZ   . ARG A 1 356 ? 9.661   -0.866  -10.652 1   63.23   ? 362  ARG A CZ   1 ? 
ATOM   5410  N  NH1  . ARG A 1 356 ? 9.132   -1.921  -11.247 1   60.896  ? 362  ARG A NH1  1 ? 
ATOM   5411  N  NH2  . ARG A 1 356 ? 9.414   0.335   -11.146 1   57.838  ? 362  ARG A NH2  1 ? 
ATOM   5412  H  H    . ARG A 1 356 ? 10.847  -1.021  -4.005  1   32.053  ? 362  ARG A H    1 c 
ATOM   5413  H  HA   . ARG A 1 356 ? 8.773   -1.896  -5.469  1   34.682  ? 362  ARG A HA   1 c 
ATOM   5414  H  HB2  . ARG A 1 356 ? 10.72   -0.904  -6.501  1   37.396  ? 362  ARG A HB2  1 c 
ATOM   5415  H  HB3  . ARG A 1 356 ? 11.47   -2.299  -6.318  1   37.461  ? 362  ARG A HB3  1 c 
ATOM   5416  H  HG2  . ARG A 1 356 ? 9.718   -3.34   -7.6    1   41.556  ? 362  ARG A HG2  1 c 
ATOM   5417  H  HG3  . ARG A 1 356 ? 9.103   -1.902  -7.863  1   41.734  ? 362  ARG A HG3  1 c 
ATOM   5418  H  HD2  . ARG A 1 356 ? 11.774  -2.192  -8.644  1   51.221  ? 362  ARG A HD2  1 c 
ATOM   5419  H  HD3  . ARG A 1 356 ? 10.717  -2.989  -9.529  1   51.509  ? 362  ARG A HD3  1 c 
ATOM   5420  H  HE   . ARG A 1 356 ? 10.746  -0.25   -9.216  1   62.378  ? 362  ARG A HE   1 c 
ATOM   5421  H  HH11 . ARG A 1 356 ? 8.748   -2.556  -10.762 1   61.435  ? 362  ARG A HH11 1 c 
ATOM   5422  H  HH12 . ARG A 1 356 ? 9.163   -1.984  -12.131 1   61.549  ? 362  ARG A HH12 1 c 
ATOM   5423  H  HH21 . ARG A 1 356 ? 9.765   1.052   -10.765 1   59.54   ? 362  ARG A HH21 1 c 
ATOM   5424  H  HH22 . ARG A 1 356 ? 8.897   0.417   -11.858 1   59.494  ? 362  ARG A HH22 1 c 
ATOM   5425  N  N    . ALA A 1 357 ? 10.68   -4.32   -4.474  1   36.142  ? 363  ALA A N    1 ? 
ATOM   5426  C  CA   . ALA A 1 357 ? 10.784  -5.763  -4.391  1   37.122  ? 363  ALA A CA   1 ? 
ATOM   5427  C  C    . ALA A 1 357 ? 9.616   -6.367  -3.615  1   34.718  ? 363  ALA A C    1 ? 
ATOM   5428  O  O    . ALA A 1 357 ? 9.219   -7.457  -3.949  1   35.08   ? 363  ALA A O    1 ? 
ATOM   5429  C  CB   . ALA A 1 357 ? 12.094  -6.176  -3.743  1   37.109  ? 363  ALA A CB   1 ? 
ATOM   5430  H  H    . ALA A 1 357 ? 11.324  -3.804  -4.08   1   36.625  ? 363  ALA A H    1 c 
ATOM   5431  H  HA   . ALA A 1 357 ? 10.757  -6.126  -5.319  1   36.449  ? 363  ALA A HA   1 c 
ATOM   5432  H  HB1  . ALA A 1 357 ? 12.839  -5.834  -4.265  1   37.113  ? 363  ALA A HB1  1 c 
ATOM   5433  H  HB2  . ALA A 1 357 ? 12.141  -5.814  -2.842  1   37.113  ? 363  ALA A HB2  1 c 
ATOM   5434  H  HB3  . ALA A 1 357 ? 12.148  -7.145  -3.703  1   37.113  ? 363  ALA A HB3  1 c 
ATOM   5435  N  N    . VAL A 1 358 ? 9.142   -5.721  -2.542  1   36.49   ? 364  VAL A N    1 ? 
ATOM   5436  C  CA   . VAL A 1 358 ? 8.097   -6.283  -1.683  1   36.224  ? 364  VAL A CA   1 ? 
ATOM   5437  C  C    . VAL A 1 358 ? 6.72    -5.715  -2.056  1   37.73   ? 364  VAL A C    1 ? 
ATOM   5438  O  O    . VAL A 1 358 ? 5.773   -5.957  -1.338  1   37.03   ? 364  VAL A O    1 ? 
ATOM   5439  C  CB   . VAL A 1 358 ? 8.342   -6.048  -0.172  1   36.995  ? 364  VAL A CB   1 ? 
ATOM   5440  C  CG1  . VAL A 1 358 ? 9.583   -6.747  0.347   1   36.407  ? 364  VAL A CG1  1 ? 
ATOM   5441  C  CG2  . VAL A 1 358 ? 8.432   -4.564  0.184   1   36.965  ? 364  VAL A CG2  1 ? 
ATOM   5442  H  H    . VAL A 1 358 ? 9.481   -4.898  -2.338  1   36.021  ? 364  VAL A H    1 c 
ATOM   5443  H  HA   . VAL A 1 358 ? 8.073   -7.248  -1.833  1   36.669  ? 364  VAL A HA   1 c 
ATOM   5444  H  HB   . VAL A 1 358 ? 7.569   -6.425  0.31    1   36.742  ? 364  VAL A HB   1 c 
ATOM   5445  H  HG11 . VAL A 1 358 ? 10.365  -6.415  -0.126  1   36.58   ? 364  VAL A HG11 1 c 
ATOM   5446  H  HG12 . VAL A 1 358 ? 9.501   -7.705  0.203   1   36.58   ? 364  VAL A HG12 1 c 
ATOM   5447  H  HG13 . VAL A 1 358 ? 9.682   -6.571  1.298   1   36.582  ? 364  VAL A HG13 1 c 
ATOM   5448  H  HG21 . VAL A 1 358 ? 8.601   -4.469  1.136   1   36.955  ? 364  VAL A HG21 1 c 
ATOM   5449  H  HG22 . VAL A 1 358 ? 7.596   -4.123  -0.04   1   36.96   ? 364  VAL A HG22 1 c 
ATOM   5450  H  HG23 . VAL A 1 358 ? 9.157   -4.153  -0.313  1   36.902  ? 364  VAL A HG23 1 c 
ATOM   5451  N  N    . GLY A 1 359 ? 6.608   -4.93   -3.124  1   34.861  ? 365  GLY A N    1 ? 
ATOM   5452  C  CA   . GLY A 1 359 ? 5.349   -4.304  -3.508  1   39.632  ? 365  GLY A CA   1 ? 
ATOM   5453  C  C    . GLY A 1 359 ? 4.795   -3.349  -2.446  1   38.227  ? 365  GLY A C    1 ? 
ATOM   5454  O  O    . GLY A 1 359 ? 3.588   -3.311  -2.223  1   34.301  ? 365  GLY A O    1 ? 
ATOM   5455  H  H    . GLY A 1 359 ? 7.345   -4.773  -3.64   1   36.559  ? 365  GLY A H    1 c 
ATOM   5456  H  HA2  . GLY A 1 359 ? 5.487   -3.808  -4.349  1   38.129  ? 365  GLY A HA2  1 c 
ATOM   5457  H  HA3  . GLY A 1 359 ? 4.685   -5.011  -3.684  1   38.129  ? 365  GLY A HA3  1 c 
ATOM   5458  N  N    . SER A 1 360 ? 5.662   -2.56   -1.8    1   36.441  ? 366  SER A N    1 ? 
ATOM   5459  C  CA   . SER A 1 360 ? 5.226   -1.54   -0.846  1   37.715  ? 366  SER A CA   1 ? 
ATOM   5460  C  C    . SER A 1 360 ? 5.171   -0.171  -1.524  1   34.442  ? 366  SER A C    1 ? 
ATOM   5461  O  O    . SER A 1 360 ? 6.205   0.476   -1.695  1   33.543  ? 366  SER A O    1 ? 
ATOM   5462  C  CB   . SER A 1 360 ? 6.095   -1.501  0.377   1   35.482  ? 366  SER A CB   1 ? 
ATOM   5463  O  OG   . SER A 1 360 ? 5.764   -0.354  1.147   1   39.888  ? 366  SER A OG   1 ? 
ATOM   5464  H  H    . SER A 1 360 ? 6.557   -2.656  -1.96   1   37.145  ? 366  SER A H    1 c 
ATOM   5465  H  HA   . SER A 1 360 ? 4.308   -1.77   -0.554  1   36.345  ? 366  SER A HA   1 c 
ATOM   5466  H  HB2  . SER A 1 360 ? 5.952   -2.308  0.907   1   36.986  ? 366  SER A HB2  1 c 
ATOM   5467  H  HB3  . SER A 1 360 ? 7.033   -1.463  0.112   1   36.956  ? 366  SER A HB3  1 c 
ATOM   5468  H  HG   . SER A 1 360 ? 6.25    -0.332  1.84    0   39.11   ? 366  SER A HG   1 c 
ATOM   5469  N  N    . GLU A 1 361 ? 3.972   0.27    -1.912  1   29.097  ? 367  GLU A N    1 ? 
ATOM   5470  C  CA   . GLU A 1 361 ? 3.844   1.585   -2.508  1   35.801  ? 367  GLU A CA   1 ? 
ATOM   5471  C  C    . GLU A 1 361 ? 4.267   2.65    -1.506  1   28.289  ? 367  GLU A C    1 ? 
ATOM   5472  O  O    . GLU A 1 361 ? 4.819   3.652   -1.923  1   29.293  ? 367  GLU A O    1 ? 
ATOM   5473  C  CB   . GLU A 1 361 ? 2.473   2.009   -3.058  1   30.959  ? 367  GLU A CB   1 ? 
ATOM   5474  C  CG   . GLU A 1 361 ? 1.996   1.104   -4.179  1   36.144  ? 367  GLU A CG   1 ? 
ATOM   5475  C  CD   . GLU A 1 361 ? 2.717   1.299   -5.502  1   46.25   ? 367  GLU A CD   1 ? 
ATOM   5476  O  OE1  . GLU A 1 361 ? 2.641   0.299   -6.254  1   50.818  ? 367  GLU A OE1  1 ? 
ATOM   5477  O  OE2  . GLU A 1 361 ? 3.302   2.369   -5.801  1   42.393  ? 367  GLU A OE2  1 ? 
ATOM   5478  H  H    . GLU A 1 361 ? 3.228   -0.251  -1.807  1   31.81   ? 367  GLU A H    1 c 
ATOM   5479  H  HA   . GLU A 1 361 ? 4.477   1.626   -3.27   1   32.108  ? 367  GLU A HA   1 c 
ATOM   5480  H  HB2  . GLU A 1 361 ? 1.819   1.99    -2.329  1   33.149  ? 367  GLU A HB2  1 c 
ATOM   5481  H  HB3  . GLU A 1 361 ? 2.531   2.932   -3.384  1   33.158  ? 367  GLU A HB3  1 c 
ATOM   5482  H  HG2  . GLU A 1 361 ? 2.106   0.17    -3.901  1   36.956  ? 367  GLU A HG2  1 c 
ATOM   5483  H  HG3  . GLU A 1 361 ? 1.038   1.257   -4.323  1   36.931  ? 367  GLU A HG3  1 c 
ATOM   5484  N  N    . GLU A 1 362 ? 3.964   2.428   -0.235  1   29.918  ? 368  GLU A N    1 ? 
ATOM   5485  C  CA   . GLU A 1 362 ? 4.361   3.291   0.85    1   33.374  ? 368  GLU A CA   1 ? 
ATOM   5486  C  C    . GLU A 1 362 ? 5.869   3.534   0.812   1   31.918  ? 368  GLU A C    1 ? 
ATOM   5487  O  O    . GLU A 1 362 ? 6.331   4.686   0.919   1   29.584  ? 368  GLU A O    1 ? 
ATOM   5488  C  CB   . GLU A 1 362 ? 3.985   2.659   2.204   1   33.302  ? 368  GLU A CB   1 ? 
ATOM   5489  C  CG   . GLU A 1 362 ? 4.385   3.55    3.385   1   31.921  ? 368  GLU A CG   1 ? 
ATOM   5490  C  CD   . GLU A 1 362 ? 4.035   3.043   4.787   1   37.048  ? 368  GLU A CD   1 ? 
ATOM   5491  O  OE1  . GLU A 1 362 ? 4.594   3.488   5.829   1   35.835  ? 368  GLU A OE1  1 ? 
ATOM   5492  O  OE2  . GLU A 1 362 ? 3.238   2.102   4.844   1   34.64   ? 368  GLU A OE2  1 ? 
ATOM   5493  H  H    . GLU A 1 362 ? 3.464   1.691   -0.032  1   30.338  ? 368  GLU A H    1 c 
ATOM   5494  H  HA   . GLU A 1 362 ? 3.892   4.158   0.751   1   32.388  ? 368  GLU A HA   1 c 
ATOM   5495  H  HB2  . GLU A 1 362 ? 3.018   2.504   2.224   1   33.009  ? 368  GLU A HB2  1 c 
ATOM   5496  H  HB3  . GLU A 1 362 ? 4.432   1.791   2.285   1   33.002  ? 368  GLU A HB3  1 c 
ATOM   5497  H  HG2  . GLU A 1 362 ? 5.354   3.695   3.354   1   33.341  ? 368  GLU A HG2  1 c 
ATOM   5498  H  HG3  . GLU A 1 362 ? 3.964   4.428   3.268   1   33.346  ? 368  GLU A HG3  1 c 
ATOM   5499  N  N    . MET A 1 363 ? 6.634   2.433   0.729   1   29.626  ? 369  MET A N    1 ? 
ATOM   5500  C  CA   . MET A 1 363 ? 8.09    2.526   0.713   1   30.411  ? 369  MET A CA   1 ? 
ATOM   5501  C  C    . MET A 1 363 ? 8.601   3.324   -0.494  1   34.135  ? 369  MET A C    1 ? 
ATOM   5502  O  O    . MET A 1 363 ? 9.446   4.233   -0.327  1   34.703  ? 369  MET A O    1 ? 
ATOM   5503  C  CB   . MET A 1 363 ? 8.694   1.117   0.771   1   33.203  ? 369  MET A CB   1 ? 
ATOM   5504  C  CG   . MET A 1 363 ? 8.739   0.577   2.196   1   30.738  ? 369  MET A CG   1 ? 
ATOM   5505  S  SD   . MET A 1 363 ? 9.674   -0.962  2.254   1   33.337  ? 369  MET A SD   1 ? 
ATOM   5506  C  CE   . MET A 1 363 ? 11.307  -0.219  2.317   1   29.685  ? 369  MET A CE   1 ? 
ATOM   5507  H  H    . MET A 1 363 ? 6.241   1.609   0.687   1   30.384  ? 369  MET A H    1 c 
ATOM   5508  H  HA   . MET A 1 363 ? 8.362   3.02    1.528   1   31.415  ? 369  MET A HA   1 c 
ATOM   5509  H  HB2  . MET A 1 363 ? 8.161   0.516   0.21    1   32.019  ? 369  MET A HB2  1 c 
ATOM   5510  H  HB3  . MET A 1 363 ? 9.604   1.145   0.406   1   31.983  ? 369  MET A HB3  1 c 
ATOM   5511  H  HG2  . MET A 1 363 ? 9.161   1.232   2.786   1   31.799  ? 369  MET A HG2  1 c 
ATOM   5512  H  HG3  . MET A 1 363 ? 7.831   0.414   2.517   1   31.878  ? 369  MET A HG3  1 c 
ATOM   5513  H  HE1  . MET A 1 363 ? 11.978  -0.919  2.42    1   30.565  ? 369  MET A HE1  1 c 
ATOM   5514  H  HE2  . MET A 1 363 ? 11.473  0.272   1.491   1   30.572  ? 369  MET A HE2  1 c 
ATOM   5515  H  HE3  . MET A 1 363 ? 11.357  0.392   3.075   1   30.575  ? 369  MET A HE3  1 c 
ATOM   5516  N  N    . MET A 1 364 ? 8.021   3.083   -1.691  1   31.713  ? 370  MET A N    1 ? 
ATOM   5517  C  CA   . MET A 1 364 ? 8.468   3.794   -2.892  1   32.161  ? 370  MET A CA   1 ? 
ATOM   5518  C  C    . MET A 1 364 ? 8.124   5.293   -2.837  1   35.979  ? 370  MET A C    1 ? 
ATOM   5519  O  O    . MET A 1 364 ? 8.989   6.153   -3.102  1   34.593  ? 370  MET A O    1 ? 
ATOM   5520  C  CB   . MET A 1 364 ? 7.922   3.146   -4.164  1   32.085  ? 370  MET A CB   1 ? 
ATOM   5521  C  CG   . MET A 1 364 ? 8.428   1.703   -4.34   1   36.963  ? 370  MET A CG   1 ? 
ATOM   5522  S  SD   . MET A 1 364 ? 7.896   0.881   -5.847  1   36.757  ? 370  MET A SD   1 ? 
ATOM   5523  C  CE   . MET A 1 364 ? 6.436   -0.047  -5.382  1   40.763  ? 370  MET A CE   1 ? 
ATOM   5524  H  H    . MET A 1 364 ? 7.345   2.472   -1.759  1   32.368  ? 370  MET A H    1 c 
ATOM   5525  H  HA   . MET A 1 364 ? 9.456   3.727   -2.916  1   32.746  ? 370  MET A HA   1 c 
ATOM   5526  H  HB2  . MET A 1 364 ? 6.941   3.144   -4.125  1   33.144  ? 370  MET A HB2  1 c 
ATOM   5527  H  HB3  . MET A 1 364 ? 8.195   3.683   -4.938  1   33.156  ? 370  MET A HB3  1 c 
ATOM   5528  H  HG2  . MET A 1 364 ? 9.406   1.709   -4.325  1   35.697  ? 370  MET A HG2  1 c 
ATOM   5529  H  HG3  . MET A 1 364 ? 8.127   1.168   -3.579  1   35.661  ? 370  MET A HG3  1 c 
ATOM   5530  H  HE1  . MET A 1 364 ? 6.088   -0.517  -6.161  1   39.72   ? 370  MET A HE1  1 c 
ATOM   5531  H  HE2  . MET A 1 364 ? 6.67    -0.693  -4.689  1   39.72   ? 370  MET A HE2  1 c 
ATOM   5532  H  HE3  . MET A 1 364 ? 5.758   0.565   -5.04   1   39.72   ? 370  MET A HE3  1 c 
ATOM   5533  N  N    . GLN A 1 365 ? 6.858   5.631   -2.529  1   40.426  ? 371  GLN A N    1 ? 
ATOM   5534  C  CA   . GLN A 1 365 ? 6.438   7.027   -2.378  1   35.215  ? 371  GLN A CA   1 ? 
ATOM   5535  C  C    . GLN A 1 365 ? 7.327   7.798   -1.387  1   32.004  ? 371  GLN A C    1 ? 
ATOM   5536  O  O    . GLN A 1 365 ? 7.655   8.959   -1.587  1   34.165  ? 371  GLN A O    1 ? 
ATOM   5537  C  CB   . GLN A 1 365 ? 5.05    7.058   -1.758  1   34.861  ? 371  GLN A CB   1 ? 
ATOM   5538  C  CG   . GLN A 1 365 ? 3.941   6.629   -2.693  1   40.082  ? 371  GLN A CG   1 ? 
ATOM   5539  C  CD   . GLN A 1 365 ? 2.645   6.357   -1.956  1   40.819  ? 371  GLN A CD   1 ? 
ATOM   5540  O  OE1  . GLN A 1 365 ? 2.454   6.658   -0.761  1   44.362  ? 371  GLN A OE1  1 ? 
ATOM   5541  N  NE2  . GLN A 1 365 ? 1.723   5.782   -2.7    1   35.171  ? 371  GLN A NE2  1 ? 
ATOM   5542  H  H    . GLN A 1 365 ? 6.239   4.97    -2.41   1   38.017  ? 371  GLN A H    1 c 
ATOM   5543  H  HA   . GLN A 1 365 ? 6.447   7.473   -3.263  1   35.475  ? 371  GLN A HA   1 c 
ATOM   5544  H  HB2  . GLN A 1 365 ? 5.048   6.471   -0.973  1   36.15   ? 371  GLN A HB2  1 c 
ATOM   5545  H  HB3  . GLN A 1 365 ? 4.865   7.969   -1.448  1   36.069  ? 371  GLN A HB3  1 c 
ATOM   5546  H  HG2  . GLN A 1 365 ? 3.788   7.332   -3.36   1   38.97   ? 371  GLN A HG2  1 c 
ATOM   5547  H  HG3  . GLN A 1 365 ? 4.213   5.818   -3.172  1   38.911  ? 371  GLN A HG3  1 c 
ATOM   5548  H  HE21 . GLN A 1 365 ? 0.944   5.557   -2.341  1   36.883  ? 371  GLN A HE21 1 c 
ATOM   5549  H  HE22 . GLN A 1 365 ? 1.879   5.619   -3.558  1   36.873  ? 371  GLN A HE22 1 c 
ATOM   5550  N  N    . PHE A 1 366 ? 7.655   7.148   -0.27   1   34.49   ? 372  PHE A N    1 ? 
ATOM   5551  C  CA   . PHE A 1 366 ? 8.467   7.706   0.807   1   34.927  ? 372  PHE A CA   1 ? 
ATOM   5552  C  C    . PHE A 1 366 ? 9.898   7.956   0.345   1   30.384  ? 372  PHE A C    1 ? 
ATOM   5553  O  O    . PHE A 1 366 ? 10.449  8.988   0.635   1   31.486  ? 372  PHE A O    1 ? 
ATOM   5554  C  CB   . PHE A 1 366 ? 8.489   6.765   2.001   1   26.801  ? 372  PHE A CB   1 ? 
ATOM   5555  C  CG   . PHE A 1 366 ? 9.389   7.176   3.155   1   31.047  ? 372  PHE A CG   1 ? 
ATOM   5556  C  CD1  . PHE A 1 366 ? 9.217   8.399   3.79    1   30.813  ? 372  PHE A CD1  1 ? 
ATOM   5557  C  CD2  . PHE A 1 366 ? 10.427  6.354   3.576   1   26.098  ? 372  PHE A CD2  1 ? 
ATOM   5558  C  CE1  . PHE A 1 366 ? 10.007  8.75    4.865   1   28.405  ? 372  PHE A CE1  1 ? 
ATOM   5559  C  CE2  . PHE A 1 366 ? 11.237  6.724   4.627   1   26.596  ? 372  PHE A CE2  1 ? 
ATOM   5560  C  CZ   . PHE A 1 366 ? 11.018  7.921   5.28    1   31.849  ? 372  PHE A CZ   1 ? 
ATOM   5561  H  H    . PHE A 1 366 ? 7.346   6.294   -0.168  1   33.939  ? 372  PHE A H    1 c 
ATOM   5562  H  HA   . PHE A 1 366 ? 8.067   8.57    1.091   1   32.373  ? 372  PHE A HA   1 c 
ATOM   5563  H  HB2  . PHE A 1 366 ? 7.57    6.676   2.338   1   29.457  ? 372  PHE A HB2  1 c 
ATOM   5564  H  HB3  . PHE A 1 366 ? 8.77    5.877   1.686   1   29.47   ? 372  PHE A HB3  1 c 
ATOM   5565  H  HD1  . PHE A 1 366 ? 8.507   8.963   3.527   1   30.243  ? 372  PHE A HD1  1 c 
ATOM   5566  H  HD2  . PHE A 1 366 ? 10.566  5.524   3.148   1   27.365  ? 372  PHE A HD2  1 c 
ATOM   5567  H  HE1  . PHE A 1 366 ? 9.872   9.58    5.294   1   29.756  ? 372  PHE A HE1  1 c 
ATOM   5568  H  HE2  . PHE A 1 366 ? 11.928  6.148   4.915   1   27.66   ? 372  PHE A HE2  1 c 
ATOM   5569  H  HZ   . PHE A 1 366 ? 11.581  8.181   5.991   1   29.706  ? 372  PHE A HZ   1 c 
ATOM   5570  N  N    . ALA A 1 367 ? 10.486  7.024   -0.406  1   33.558  ? 373  ALA A N    1 ? 
ATOM   5571  C  CA   . ALA A 1 367 ? 11.777  7.265   -1.007  1   31.819  ? 373  ALA A CA   1 ? 
ATOM   5572  C  C    . ALA A 1 367 ? 11.733  8.516   -1.878  1   30.546  ? 373  ALA A C    1 ? 
ATOM   5573  O  O    . ALA A 1 367 ? 12.644  9.332   -1.778  1   27.016  ? 373  ALA A O    1 ? 
ATOM   5574  C  CB   . ALA A 1 367 ? 12.213  6.063   -1.811  1   34.598  ? 373  ALA A CB   1 ? 
ATOM   5575  H  H    . ALA A 1 367 ? 10.074  6.219   -0.54   1   32.425  ? 373  ALA A H    1 c 
ATOM   5576  H  HA   . ALA A 1 367 ? 12.435  7.421   -0.275  1   32.365  ? 373  ALA A HA   1 c 
ATOM   5577  H  HB1  . ALA A 1 367 ? 12.304  5.293   -1.225  1   33.703  ? 373  ALA A HB1  1 c 
ATOM   5578  H  HB2  . ALA A 1 367 ? 11.552  5.869   -2.496  1   33.739  ? 373  ALA A HB2  1 c 
ATOM   5579  H  HB3  . ALA A 1 367 ? 13.069  6.246   -2.234  1   33.718  ? 373  ALA A HB3  1 c 
ATOM   5580  N  N    . ALA A 1 368 ? 10.727  8.633   -2.775  1   30.301  ? 374  ALA A N    1 ? 
ATOM   5581  C  CA   . ALA A 1 368 ? 10.547  9.849   -3.56   1   29.047  ? 374  ALA A CA   1 ? 
ATOM   5582  C  C    . ALA A 1 368 ? 10.379  11.066  -2.657  1   31.061  ? 374  ALA A C    1 ? 
ATOM   5583  O  O    . ALA A 1 368 ? 10.899  12.134  -2.976  1   31.702  ? 374  ALA A O    1 ? 
ATOM   5584  C  CB   . ALA A 1 368 ? 9.397   9.756   -4.525  1   28.644  ? 374  ALA A CB   1 ? 
ATOM   5585  H  H    . ALA A 1 368 ? 10.148  7.937   -2.897  1   30.094  ? 374  ALA A H    1 c 
ATOM   5586  H  HA   . ALA A 1 368 ? 11.381  9.986   -4.088  1   29.572  ? 374  ALA A HA   1 c 
ATOM   5587  H  HB1  . ALA A 1 368 ? 9.588   9.08    -5.196  1   28.788  ? 374  ALA A HB1  1 c 
ATOM   5588  H  HB2  . ALA A 1 368 ? 8.588   9.512   -4.046  1   28.838  ? 374  ALA A HB2  1 c 
ATOM   5589  H  HB3  . ALA A 1 368 ? 9.265   10.614  -4.963  1   28.817  ? 374  ALA A HB3  1 c 
ATOM   5590  N  N    . TYR A 1 369 ? 9.646   10.912  -1.552  1   29.576  ? 375  TYR A N    1 ? 
ATOM   5591  C  CA   . TYR A 1 369 ? 9.432   12.006  -0.602  1   34.507  ? 375  TYR A CA   1 ? 
ATOM   5592  C  C    . TYR A 1 369 ? 10.745  12.501  0.033   1   39.684  ? 375  TYR A C    1 ? 
ATOM   5593  O  O    . TYR A 1 369 ? 10.944  13.712  0.198   1   35.387  ? 375  TYR A O    1 ? 
ATOM   5594  C  CB   . TYR A 1 369 ? 8.491   11.499  0.497   1   36.852  ? 375  TYR A CB   1 ? 
ATOM   5595  C  CG   . TYR A 1 369 ? 8.082   12.506  1.561   1   40.075  ? 375  TYR A CG   1 ? 
ATOM   5596  C  CD1  . TYR A 1 369 ? 7.084   13.428  1.3     1   42.364  ? 375  TYR A CD1  1 ? 
ATOM   5597  C  CD2  . TYR A 1 369 ? 8.674   12.501  2.827   1   42.584  ? 375  TYR A CD2  1 ? 
ATOM   5598  C  CE1  . TYR A 1 369 ? 6.664   14.32   2.279   1   50.921  ? 375  TYR A CE1  1 ? 
ATOM   5599  C  CE2  . TYR A 1 369 ? 8.267   13.386  3.81    1   42.398  ? 375  TYR A CE2  1 ? 
ATOM   5600  C  CZ   . TYR A 1 369 ? 7.261   14.295  3.531   1   42.766  ? 375  TYR A CZ   1 ? 
ATOM   5601  O  OH   . TYR A 1 369 ? 6.859   15.153  4.506   1   64.473  ? 375  TYR A OH   1 ? 
ATOM   5602  H  H    . TYR A 1 369 ? 9.254   10.104  -1.386  1   31.034  ? 375  TYR A H    1 c 
ATOM   5603  H  HA   . TYR A 1 369 ? 8.998   12.763  -1.075  1   34.812  ? 375  TYR A HA   1 c 
ATOM   5604  H  HB2  . TYR A 1 369 ? 7.678   11.154  0.067   1   36.958  ? 375  TYR A HB2  1 c 
ATOM   5605  H  HB3  . TYR A 1 369 ? 8.924   10.74   0.943   1   36.958  ? 375  TYR A HB3  1 c 
ATOM   5606  H  HD1  . TYR A 1 369 ? 6.665   13.435  0.455   1   43.645  ? 375  TYR A HD1  1 c 
ATOM   5607  H  HD2  . TYR A 1 369 ? 9.347   11.869  3.023   1   42.008  ? 375  TYR A HD2  1 c 
ATOM   5608  H  HE1  . TYR A 1 369 ? 5.98    14.941  2.094   1   46.833  ? 375  TYR A HE1  1 c 
ATOM   5609  H  HE2  . TYR A 1 369 ? 8.668   13.369  4.662   1   42.638  ? 375  TYR A HE2  1 c 
ATOM   5610  H  HH   . TYR A 1 369 ? 6.213   14.809  4.941   0   62.7    ? 375  TYR A HH   1 c 
ATOM   5611  N  N    . LEU A 1 370 ? 11.634  11.566  0.386   1   33.657  ? 376  LEU A N    1 ? 
ATOM   5612  C  CA   . LEU A 1 370 ? 12.912  11.907  0.976   1   31.581  ? 376  LEU A CA   1 ? 
ATOM   5613  C  C    . LEU A 1 370 ? 13.734  12.764  0.026   1   33.429  ? 376  LEU A C    1 ? 
ATOM   5614  O  O    . LEU A 1 370 ? 14.568  13.508  0.508   1   32.441  ? 376  LEU A O    1 ? 
ATOM   5615  C  CB   . LEU A 1 370 ? 13.714  10.673  1.412   1   32.78   ? 376  LEU A CB   1 ? 
ATOM   5616  C  CG   . LEU A 1 370 ? 13.128  9.919   2.619   1   31.177  ? 376  LEU A CG   1 ? 
ATOM   5617  C  CD1  . LEU A 1 370 ? 13.875  8.638   2.905   1   28.652  ? 376  LEU A CD1  1 ? 
ATOM   5618  C  CD2  . LEU A 1 370 ? 13.066  10.809  3.869   1   33.422  ? 376  LEU A CD2  1 ? 
ATOM   5619  H  H    . LEU A 1 370 ? 11.432  10.684  0.258   1   34.459  ? 376  LEU A H    1 c 
ATOM   5620  H  HA   . LEU A 1 370 ? 12.727  12.459  1.777   1   32.586  ? 376  LEU A HA   1 c 
ATOM   5621  H  HB2  . LEU A 1 370 ? 13.765  10.052  0.65    1   32.139  ? 376  LEU A HB2  1 c 
ATOM   5622  H  HB3  . LEU A 1 370 ? 14.628  10.961  1.637   1   32.145  ? 376  LEU A HB3  1 c 
ATOM   5623  H  HG   . LEU A 1 370 ? 12.196  9.67    2.393   1   31.368  ? 376  LEU A HG   1 c 
ATOM   5624  H  HD11 . LEU A 1 370 ? 13.812  8.047   2.136   1   29.382  ? 376  LEU A HD11 1 c 
ATOM   5625  H  HD12 . LEU A 1 370 ? 13.486  8.201   3.681   1   29.388  ? 376  LEU A HD12 1 c 
ATOM   5626  H  HD13 . LEU A 1 370 ? 14.809  8.839   3.083   1   29.382  ? 376  LEU A HD13 1 c 
ATOM   5627  H  HD21 . LEU A 1 370 ? 12.386  11.494  3.749   1   32.736  ? 376  LEU A HD21 1 c 
ATOM   5628  H  HD22 . LEU A 1 370 ? 13.929  11.232  4.011   1   32.741  ? 376  LEU A HD22 1 c 
ATOM   5629  H  HD23 . LEU A 1 370 ? 12.841  10.266  4.643   1   32.722  ? 376  LEU A HD23 1 c 
ATOM   5630  N  N    . LEU A 1 371 ? 13.537  12.659  -1.298  1   37.799  ? 377  LEU A N    1 ? 
ATOM   5631  C  CA   . LEU A 1 371 ? 14.322  13.448  -2.232  1   36.451  ? 377  LEU A CA   1 ? 
ATOM   5632  C  C    . LEU A 1 371 ? 13.951  14.936  -2.189  1   40.676  ? 377  LEU A C    1 ? 
ATOM   5633  O  O    . LEU A 1 371 ? 14.755  15.79   -2.598  1   42.228  ? 377  LEU A O    1 ? 
ATOM   5634  C  CB   . LEU A 1 371 ? 14.226  12.877  -3.632  1   34.856  ? 377  LEU A CB   1 ? 
ATOM   5635  C  CG   . LEU A 1 371 ? 14.836  11.48   -3.809  1   42.132  ? 377  LEU A CG   1 ? 
ATOM   5636  C  CD1  . LEU A 1 371 ? 14.703  11.039  -5.253  1   40.273  ? 377  LEU A CD1  1 ? 
ATOM   5637  C  CD2  . LEU A 1 371 ? 16.284  11.425  -3.388  1   38.601  ? 377  LEU A CD2  1 ? 
ATOM   5638  H  H    . LEU A 1 371 ? 12.913  12.077  -1.624  1   36.366  ? 377  LEU A H    1 c 
ATOM   5639  H  HA   . LEU A 1 371 ? 15.266  13.386  -1.942  1   37.129  ? 377  LEU A HA   1 c 
ATOM   5640  H  HB2  . LEU A 1 371 ? 13.276  12.839  -3.887  1   36.744  ? 377  LEU A HB2  1 c 
ATOM   5641  H  HB3  . LEU A 1 371 ? 14.682  13.495  -4.247  1   36.823  ? 377  LEU A HB3  1 c 
ATOM   5642  H  HG   . LEU A 1 371 ? 14.325  10.844  -3.244  1   39.615  ? 377  LEU A HG   1 c 
ATOM   5643  H  HD11 . LEU A 1 371 ? 13.764  11.026  -5.503  1   40.813  ? 377  LEU A HD11 1 c 
ATOM   5644  H  HD12 . LEU A 1 371 ? 15.077  10.149  -5.358  1   40.807  ? 377  LEU A HD12 1 c 
ATOM   5645  H  HD13 . LEU A 1 371 ? 15.181  11.66   -5.827  1   40.815  ? 377  LEU A HD13 1 c 
ATOM   5646  H  HD21 . LEU A 1 371 ? 16.346  11.492  -2.421  1   39.585  ? 377  LEU A HD21 1 c 
ATOM   5647  H  HD22 . LEU A 1 371 ? 16.769  12.163  -3.795  1   39.613  ? 377  LEU A HD22 1 c 
ATOM   5648  H  HD23 . LEU A 1 371 ? 16.675  10.583  -3.678  1   39.622  ? 377  LEU A HD23 1 c 
ATOM   5649  N  N    . ASP A 1 372 ? 12.767  15.255  -1.667  1   44.251  ? 378  ASP A N    1 ? 
ATOM   5650  C  CA   . ASP A 1 372 ? 12.339  16.631  -1.402  1   45.894  ? 378  ASP A CA   1 ? 
ATOM   5651  C  C    . ASP A 1 372 ? 12.391  17.476  -2.676  1   45.602  ? 378  ASP A C    1 ? 
ATOM   5652  O  O    . ASP A 1 372 ? 12.775  18.635  -2.627  1   50.824  ? 378  ASP A O    1 ? 
ATOM   5653  C  CB   . ASP A 1 372 ? 13.149  17.211  -0.249  1   50.352  ? 378  ASP A CB   1 ? 
ATOM   5654  C  CG   . ASP A 1 372 ? 12.729  18.565  0.328   1   54.634  ? 378  ASP A CG   1 ? 
ATOM   5655  O  OD1  . ASP A 1 372 ? 11.597  19.016  0.082   1   58.317  ? 378  ASP A OD1  1 ? 
ATOM   5656  O  OD2  . ASP A 1 372 ? 13.56   19.183  1.016   1   62.801  ? 378  ASP A OD2  1 ? 
ATOM   5657  H  H    . ASP A 1 372 ? 12.179  14.581  -1.476  1   43.543  ? 378  ASP A H    1 c 
ATOM   5658  H  HA   . ASP A 1 372 ? 11.404  16.6    -1.098  1   46.386  ? 378  ASP A HA   1 c 
ATOM   5659  H  HB2  . ASP A 1 372 ? 13.135  16.562  0.485   1   50.223  ? 378  ASP A HB2  1 c 
ATOM   5660  H  HB3  . ASP A 1 372 ? 14.079  17.298  -0.543  1   50.223  ? 378  ASP A HB3  1 c 
ATOM   5661  N  N    . GLY A 1 373 ? 11.994  16.906  -3.818  1   48.556  ? 379  GLY A N    1 ? 
ATOM   5662  C  CA   . GLY A 1 373 ? 11.991  17.617  -5.089  1   53.098  ? 379  GLY A CA   1 ? 
ATOM   5663  C  C    . GLY A 1 373 ? 13.366  17.693  -5.765  1   56.981  ? 379  GLY A C    1 ? 
ATOM   5664  O  O    . GLY A 1 373 ? 13.59   18.533  -6.632  1   53.834  ? 379  GLY A O    1 ? 
ATOM   5665  H  H    . GLY A 1 373 ? 11.707  16.038  -3.806  1   48.758  ? 379  GLY A H    1 c 
ATOM   5666  H  HA2  . GLY A 1 373 ? 11.359  17.167  -5.697  1   52.786  ? 379  GLY A HA2  1 c 
ATOM   5667  H  HA3  . GLY A 1 373 ? 11.655  18.532  -4.938  1   52.744  ? 379  GLY A HA3  1 c 
ATOM   5668  N  N    . LYS A 1 374 ? 14.292  16.795  -5.408  1   57.96   ? 380  LYS A N    1 ? 
ATOM   5669  C  CA   . LYS A 1 374 ? 15.601  16.766  -6.044  1   48.807  ? 380  LYS A CA   1 ? 
ATOM   5670  C  C    . LYS A 1 374 ? 15.756  15.428  -6.75   1   45.707  ? 380  LYS A C    1 ? 
ATOM   5671  O  O    . LYS A 1 374 ? 15.075  14.447  -6.446  1   45.243  ? 380  LYS A O    1 ? 
ATOM   5672  C  CB   . LYS A 1 374 ? 16.756  16.991  -5.056  1   52.793  ? 380  LYS A CB   1 ? 
ATOM   5673  C  CG   . LYS A 1 374 ? 16.55   18.156  -4.066  1   62.566  ? 380  LYS A CG   1 ? 
ATOM   5674  C  CD   . LYS A 1 374 ? 17.407  18.155  -2.799  1   62.711  ? 380  LYS A CD   1 ? 
ATOM   5675  C  CE   . LYS A 1 374 ? 16.732  18.657  -1.541  1   63.812  ? 380  LYS A CE   1 ? 
ATOM   5676  N  NZ   . LYS A 1 374 ? 15.841  19.82   -1.718  1   66.995  ? 380  LYS A NZ   1 ? 
ATOM   5677  H  H    . LYS A 1 374 ? 14.103  16.181  -4.758  1   55.368  ? 380  LYS A H    1 c 
ATOM   5678  H  HA   . LYS A 1 374 ? 15.635  17.484  -6.726  1   50.618  ? 380  LYS A HA   1 c 
ATOM   5679  H  HB2  . LYS A 1 374 ? 16.892  16.167  -4.541  1   53.907  ? 380  LYS A HB2  1 c 
ATOM   5680  H  HB3  . LYS A 1 374 ? 17.577  17.161  -5.567  1   53.9    ? 380  LYS A HB3  1 c 
ATOM   5681  H  HG2  . LYS A 1 374 ? 16.714  18.995  -4.549  1   60.243  ? 380  LYS A HG2  1 c 
ATOM   5682  H  HG3  . LYS A 1 374 ? 15.605  18.162  -3.799  1   60.305  ? 380  LYS A HG3  1 c 
ATOM   5683  H  HD2  . LYS A 1 374 ? 17.701  17.235  -2.643  1   62.804  ? 380  LYS A HD2  1 c 
ATOM   5684  H  HD3  . LYS A 1 374 ? 18.208  18.698  -2.964  1   62.905  ? 380  LYS A HD3  1 c 
ATOM   5685  H  HE2  . LYS A 1 374 ? 16.212  17.928  -1.16   1   64.182  ? 380  LYS A HE2  1 c 
ATOM   5686  H  HE3  . LYS A 1 374 ? 17.419  18.894  -0.892  1   64.274  ? 380  LYS A HE3  1 c 
ATOM   5687  H  HZ1  . LYS A 1 374 ? 15.032  19.544  -2.023  1   65.94   ? 380  LYS A HZ1  1 c 
ATOM   5688  H  HZ2  . LYS A 1 374 ? 16.203  20.398  -2.315  1   65.984  ? 380  LYS A HZ2  1 c 
ATOM   5689  H  HZ3  . LYS A 1 374 ? 15.73   20.242  -0.923  1   65.985  ? 380  LYS A HZ3  1 c 
ATOM   5690  N  N    . ARG A 1 375 ? 16.67   15.417  -7.707  1   47.007  ? 381  ARG A N    1 ? 
ATOM   5691  C  CA   . ARG A 1 375 ? 16.982  14.232  -8.484  1   52.306  ? 381  ARG A CA   1 ? 
ATOM   5692  C  C    . ARG A 1 375 ? 17.801  13.272  -7.622  1   42.445  ? 381  ARG A C    1 ? 
ATOM   5693  O  O    . ARG A 1 375 ? 18.653  13.69   -6.855  1   37.928  ? 381  ARG A O    1 ? 
ATOM   5694  C  CB   . ARG A 1 375 ? 17.745  14.648  -9.751  1   56.465  ? 381  ARG A CB   1 ? 
ATOM   5695  C  CG   . ARG A 1 375 ? 16.903  15.075  -10.954 1   67.338  ? 381  ARG A CG   1 ? 
ATOM   5696  C  CD   . ARG A 1 375 ? 17.713  15.214  -12.258 1   72.541  ? 381  ARG A CD   1 ? 
ATOM   5697  N  NE   . ARG A 1 375 ? 18.789  14.214  -12.239 1   82.931  ? 381  ARG A NE   1 ? 
ATOM   5698  C  CZ   . ARG A 1 375 ? 18.818  13.031  -12.848 1   88.633  ? 381  ARG A CZ   1 ? 
ATOM   5699  N  NH1  . ARG A 1 375 ? 18.177  12.842  -13.989 1   97.116  ? 381  ARG A NH1  1 ? 
ATOM   5700  N  NH2  . ARG A 1 375 ? 19.565  12.062  -12.341 1   85.271  ? 381  ARG A NH2  1 ? 
ATOM   5701  H  H    . ARG A 1 375 ? 17.129  16.188  -7.885  1   48.001  ? 381  ARG A H    1 c 
ATOM   5702  H  HA   . ARG A 1 375 ? 16.131  13.797  -8.743  1   49.821  ? 381  ARG A HA   1 c 
ATOM   5703  H  HB2  . ARG A 1 375 ? 18.346  15.388  -9.519  1   57.658  ? 381  ARG A HB2  1 c 
ATOM   5704  H  HB3  . ARG A 1 375 ? 18.307  13.891  -10.02  1   57.931  ? 381  ARG A HB3  1 c 
ATOM   5705  H  HG2  . ARG A 1 375 ? 16.191  14.413  -11.095 1   65.783  ? 381  ARG A HG2  1 c 
ATOM   5706  H  HG3  . ARG A 1 375 ? 16.472  15.935  -10.756 1   65.785  ? 381  ARG A HG3  1 c 
ATOM   5707  H  HD2  . ARG A 1 375 ? 17.135  15.062  -13.033 1   73.955  ? 381  ARG A HD2  1 c 
ATOM   5708  H  HD3  . ARG A 1 375 ? 18.098  16.111  -12.325 1   73.717  ? 381  ARG A HD3  1 c 
ATOM   5709  H  HE   . ARG A 1 375 ? 19.51   14.425  -11.797 1   81.298  ? 381  ARG A HE   1 c 
ATOM   5710  H  HH11 . ARG A 1 375 ? 18.089  13.51   -14.561 1   94.101  ? 381  ARG A HH11 1 c 
ATOM   5711  H  HH12 . ARG A 1 375 ? 17.842  12.045  -14.176 1   94.347  ? 381  ARG A HH12 1 c 
ATOM   5712  H  HH21 . ARG A 1 375 ? 19.818  12.1    -11.493 1   86.243  ? 381  ARG A HH21 1 c 
ATOM   5713  H  HH22 . ARG A 1 375 ? 19.805  11.377  -12.847 1   86.353  ? 381  ARG A HH22 1 c 
ATOM   5714  N  N    . PRO A 1 376 ? 17.562  11.95   -7.705  1   41.422  ? 382  PRO A N    1 ? 
ATOM   5715  C  CA   . PRO A 1 376 ? 18.36   10.99   -6.946  1   39.137  ? 382  PRO A CA   1 ? 
ATOM   5716  C  C    . PRO A 1 376 ? 19.808  10.97   -7.42   1   42.045  ? 382  PRO A C    1 ? 
ATOM   5717  O  O    . PRO A 1 376 ? 20.085  11.289  -8.562  1   37.552  ? 382  PRO A O    1 ? 
ATOM   5718  C  CB   . PRO A 1 376 ? 17.659  9.647   -7.222  1   40.834  ? 382  PRO A CB   1 ? 
ATOM   5719  C  CG   . PRO A 1 376 ? 16.841  9.865   -8.478  1   42.219  ? 382  PRO A CG   1 ? 
ATOM   5720  C  CD   . PRO A 1 376 ? 16.506  11.333  -8.518  1   40.487  ? 382  PRO A CD   1 ? 
ATOM   5721  H  HA   . PRO A 1 376 ? 18.316  11.204  -5.98   1   40.381  ? 382  PRO A HA   1 c 
ATOM   5722  H  HB2  . PRO A 1 376 ? 18.319  8.928   -7.356  1   40.735  ? 382  PRO A HB2  1 c 
ATOM   5723  H  HB3  . PRO A 1 376 ? 17.076  9.398   -6.466  1   40.724  ? 382  PRO A HB3  1 c 
ATOM   5724  H  HG2  . PRO A 1 376 ? 17.356  9.61    -9.272  1   41.504  ? 382  PRO A HG2  1 c 
ATOM   5725  H  HG3  . PRO A 1 376 ? 16.022  9.327   -8.453  1   41.504  ? 382  PRO A HG3  1 c 
ATOM   5726  H  HD2  . PRO A 1 376 ? 16.526  11.671  -9.441  1   41.202  ? 382  PRO A HD2  1 c 
ATOM   5727  H  HD3  . PRO A 1 376 ? 15.618  11.503  -8.133  1   41.159  ? 382  PRO A HD3  1 c 
ATOM   5728  N  N    . SER A 1 377 ? 20.733  10.5    -6.578  1   41.723  ? 383  SER A N    1 ? 
ATOM   5729  C  CA   . SER A 1 377 ? 22.098  10.378  -7.062  1   39.602  ? 383  SER A CA   1 ? 
ATOM   5730  C  C    . SER A 1 377 ? 22.655  8.956   -6.896  1   41.619  ? 383  SER A C    1 ? 
ATOM   5731  O  O    . SER A 1 377 ? 22.257  8.158   -6.033  1   33.833  ? 383  SER A O    1 ? 
ATOM   5732  C  CB   . SER A 1 377 ? 22.969  11.438  -6.452  1   42.557  ? 383  SER A CB   1 ? 
ATOM   5733  O  OG   . SER A 1 377 ? 22.882  11.4    -5.044  1   50.852  ? 383  SER A OG   1 ? 
ATOM   5734  H  H    . SER A 1 377 ? 20.523  10.258  -5.722  1   41.302  ? 383  SER A H    1 c 
ATOM   5735  H  HA   . SER A 1 377 ? 22.075  10.557  -8.035  1   40.863  ? 383  SER A HA   1 c 
ATOM   5736  H  HB2  . SER A 1 377 ? 23.895  11.294  -6.726  1   43.669  ? 383  SER A HB2  1 c 
ATOM   5737  H  HB3  . SER A 1 377 ? 22.686  12.315  -6.773  1   43.678  ? 383  SER A HB3  1 c 
ATOM   5738  H  HG   . SER A 1 377 ? 23.369  12.044  -4.76   0   50.23   ? 383  SER A HG   1 c 
ATOM   5739  N  N    . VAL A 1 378 ? 23.54   8.616   -7.834  1   37.275  ? 384  VAL A N    1 ? 
ATOM   5740  C  CA   . VAL A 1 378 ? 24.344  7.423   -7.73   1   38.248  ? 384  VAL A CA   1 ? 
ATOM   5741  C  C    . VAL A 1 378 ? 25.378  7.634   -6.63   1   37.241  ? 384  VAL A C    1 ? 
ATOM   5742  O  O    . VAL A 1 378 ? 26.202  8.539   -6.748  1   34.616  ? 384  VAL A O    1 ? 
ATOM   5743  C  CB   . VAL A 1 378 ? 25.042  7.058   -9.047  1   36.205  ? 384  VAL A CB   1 ? 
ATOM   5744  C  CG1  . VAL A 1 378 ? 25.907  5.83    -8.816  1   38.266  ? 384  VAL A CG1  1 ? 
ATOM   5745  C  CG2  . VAL A 1 378 ? 24.029  6.834   -10.162 1   36.691  ? 384  VAL A CG2  1 ? 
ATOM   5746  H  H    . VAL A 1 378 ? 23.65   9.156   -8.563  1   38.479  ? 384  VAL A H    1 c 
ATOM   5747  H  HA   . VAL A 1 378 ? 23.761  6.683   -7.477  1   37.423  ? 384  VAL A HA   1 c 
ATOM   5748  H  HB   . VAL A 1 378 ? 25.625  7.814   -9.295  1   37.033  ? 384  VAL A HB   1 c 
ATOM   5749  H  HG11 . VAL A 1 378 ? 25.391  5.151   -8.348  1   37.649  ? 384  VAL A HG11 1 c 
ATOM   5750  H  HG12 . VAL A 1 378 ? 26.683  6.071   -8.282  1   37.645  ? 384  VAL A HG12 1 c 
ATOM   5751  H  HG13 . VAL A 1 378 ? 26.203  5.477   -9.672  1   37.646  ? 384  VAL A HG13 1 c 
ATOM   5752  H  HG21 . VAL A 1 378 ? 24.494  6.572   -10.975 1   36.565  ? 384  VAL A HG21 1 c 
ATOM   5753  H  HG22 . VAL A 1 378 ? 23.535  7.655   -10.324 1   36.623  ? 384  VAL A HG22 1 c 
ATOM   5754  H  HG23 . VAL A 1 378 ? 23.411  6.131   -9.903  1   36.565  ? 384  VAL A HG23 1 c 
ATOM   5755  N  N    . PRO A 1 379 ? 25.357  6.819   -5.54   1   34.667  ? 385  PRO A N    1 ? 
ATOM   5756  C  CA   . PRO A 1 379 ? 26.307  6.979   -4.438  1   37.575  ? 385  PRO A CA   1 ? 
ATOM   5757  C  C    . PRO A 1 379 ? 27.688  6.444   -4.816  1   37.539  ? 385  PRO A C    1 ? 
ATOM   5758  O  O    . PRO A 1 379 ? 27.797  5.46    -5.535  1   30.821  ? 385  PRO A O    1 ? 
ATOM   5759  C  CB   . PRO A 1 379 ? 25.626  6.15    -3.316  1   35.139  ? 385  PRO A CB   1 ? 
ATOM   5760  C  CG   . PRO A 1 379 ? 24.996  4.989   -4.074  1   33.57   ? 385  PRO A CG   1 ? 
ATOM   5761  C  CD   . PRO A 1 379 ? 24.463  5.643   -5.346  1   35.09   ? 385  PRO A CD   1 ? 
ATOM   5762  H  HA   . PRO A 1 379 ? 26.361  7.931   -4.174  1   36.562  ? 385  PRO A HA   1 c 
ATOM   5763  H  HB2  . PRO A 1 379 ? 26.29   5.828   -2.662  1   35.307  ? 385  PRO A HB2  1 c 
ATOM   5764  H  HB3  . PRO A 1 379 ? 24.941  6.683   -2.849  1   35.298  ? 385  PRO A HB3  1 c 
ATOM   5765  H  HG2  . PRO A 1 379 ? 25.662  4.302   -4.285  1   34.266  ? 385  PRO A HG2  1 c 
ATOM   5766  H  HG3  . PRO A 1 379 ? 24.27   4.582   -3.557  1   34.309  ? 385  PRO A HG3  1 c 
ATOM   5767  H  HD2  . PRO A 1 379 ? 24.524  5.025   -6.107  1   34.588  ? 385  PRO A HD2  1 c 
ATOM   5768  H  HD3  . PRO A 1 379 ? 23.528  5.923   -5.232  1   34.65   ? 385  PRO A HD3  1 c 
ATOM   5769  N  N    . LEU A 1 380 ? 28.739  7.104   -4.321  1   41.798  ? 386  LEU A N    1 ? 
ATOM   5770  C  CA   . LEU A 1 380 ? 30.1    6.649   -4.558  1   39.23   ? 386  LEU A CA   1 ? 
ATOM   5771  C  C    . LEU A 1 380 ? 30.459  5.645   -3.459  1   34.804  ? 386  LEU A C    1 ? 
ATOM   5772  O  O    . LEU A 1 380 ? 30.121  4.478   -3.593  1   41.556  ? 386  LEU A O    1 ? 
ATOM   5773  C  CB   . LEU A 1 380 ? 31.021  7.867   -4.683  1   39.13   ? 386  LEU A CB   1 ? 
ATOM   5774  C  CG   . LEU A 1 380 ? 30.661  8.795   -5.865  1   45.011  ? 386  LEU A CG   1 ? 
ATOM   5775  C  CD1  . LEU A 1 380 ? 31.533  10.044  -5.922  1   46.55   ? 386  LEU A CD1  1 ? 
ATOM   5776  C  CD2  . LEU A 1 380 ? 30.731  8.089   -7.219  1   38.249  ? 386  LEU A CD2  1 ? 
ATOM   5777  H  H    . LEU A 1 380 ? 28.606  7.857   -3.82   1   40.107  ? 386  LEU A H    1 c 
ATOM   5778  H  HA   . LEU A 1 380 ? 30.111  6.16    -5.419  1   38.776  ? 386  LEU A HA   1 c 
ATOM   5779  H  HB2  . LEU A 1 380 ? 30.966  8.388   -3.849  1   40.357  ? 386  LEU A HB2  1 c 
ATOM   5780  H  HB3  . LEU A 1 380 ? 31.944  7.552   -4.803  1   40.366  ? 386  LEU A HB3  1 c 
ATOM   5781  H  HG   . LEU A 1 380 ? 29.725  9.096   -5.737  1   42.822  ? 386  LEU A HG   1 c 
ATOM   5782  H  HD11 . LEU A 1 380 ? 31.442  10.543  -5.093  1   46.081  ? 386  LEU A HD11 1 c 
ATOM   5783  H  HD12 . LEU A 1 380 ? 31.254  10.603  -6.667  1   46.047  ? 386  LEU A HD12 1 c 
ATOM   5784  H  HD13 . LEU A 1 380 ? 32.463  9.786   -6.043  1   46.081  ? 386  LEU A HD13 1 c 
ATOM   5785  H  HD21 . LEU A 1 380 ? 29.996  7.458   -7.296  1   40.127  ? 386  LEU A HD21 1 c 
ATOM   5786  H  HD22 . LEU A 1 380 ? 31.575  7.613   -7.294  1   40.138  ? 386  LEU A HD22 1 c 
ATOM   5787  H  HD23 . LEU A 1 380 ? 30.667  8.746   -7.933  1   40.195  ? 386  LEU A HD23 1 c 
ATOM   5788  N  N    . GLY A 1 381 ? 31.104  6.061   -2.373  1   36.402  ? 387  GLY A N    1 ? 
ATOM   5789  C  CA   . GLY A 1 381 ? 31.169  5.19    -1.202  1   31.866  ? 387  GLY A CA   1 ? 
ATOM   5790  C  C    . GLY A 1 381 ? 31.973  3.913   -1.478  1   32.789  ? 387  GLY A C    1 ? 
ATOM   5791  O  O    . GLY A 1 381 ? 32.728  3.827   -2.458  1   32.125  ? 387  GLY A O    1 ? 
ATOM   5792  H  H    . GLY A 1 381 ? 31.51   6.88    -2.349  1   35.03   ? 387  GLY A H    1 c 
ATOM   5793  H  HA2  . GLY A 1 381 ? 31.584  5.683   -0.458  1   33.278  ? 387  GLY A HA2  1 c 
ATOM   5794  H  HA3  . GLY A 1 381 ? 30.252  4.949   -0.931  1   33.178  ? 387  GLY A HA3  1 c 
ATOM   5795  N  N    . ASN A 1 382 ? 31.732  2.889   -0.651  1   32.207  ? 388  ASN A N    1 ? 
ATOM   5796  C  CA   . ASN A 1 382 ? 32.516  1.665   -0.652  1   35.2    ? 388  ASN A CA   1 ? 
ATOM   5797  C  C    . ASN A 1 382 ? 31.613  0.453   -0.919  1   35.195  ? 388  ASN A C    1 ? 
ATOM   5798  O  O    . ASN A 1 382 ? 32.073  -0.693  -0.825  1   36.176  ? 388  ASN A O    1 ? 
ATOM   5799  C  CB   . ASN A 1 382 ? 33.307  1.578   0.645   1   31.628  ? 388  ASN A CB   1 ? 
ATOM   5800  C  CG   . ASN A 1 382 ? 32.352  1.546   1.81    1   34.769  ? 388  ASN A CG   1 ? 
ATOM   5801  O  OD1  . ASN A 1 382 ? 31.287  0.941   1.733   1   34.005  ? 388  ASN A OD1  1 ? 
ATOM   5802  N  ND2  . ASN A 1 382 ? 32.693  2.179   2.903   1   40.699  ? 388  ASN A ND2  1 ? 
ATOM   5803  H  H    . ASN A 1 382 ? 31.045  2.964   -0.053  1   33.056  ? 388  ASN A H    1 c 
ATOM   5804  H  HA   . ASN A 1 382 ? 33.168  1.721   -1.385  1   33.896  ? 388  ASN A HA   1 c 
ATOM   5805  H  HB2  . ASN A 1 382 ? 33.853  0.766   0.644   1   33.13   ? 388  ASN A HB2  1 c 
ATOM   5806  H  HB3  . ASN A 1 382 ? 33.9    2.352   0.723   1   33.191  ? 388  ASN A HB3  1 c 
ATOM   5807  H  HD21 . ASN A 1 382 ? 32.194  2.102   3.633   1   38.705  ? 388  ASN A HD21 1 c 
ATOM   5808  H  HD22 . ASN A 1 382 ? 33.421  2.687   2.916   1   38.646  ? 388  ASN A HD22 1 c 
ATOM   5809  N  N    . ASP A 1 383 ? 30.359  0.7     -1.32   1   36.624  ? 389  ASP A N    1 ? 
ATOM   5810  C  CA   . ASP A 1 383 ? 29.372  -0.377  -1.514  1   38.68   ? 389  ASP A CA   1 ? 
ATOM   5811  C  C    . ASP A 1 383 ? 28.998  -0.536  -2.992  1   32.367  ? 389  ASP A C    1 ? 
ATOM   5812  O  O    . ASP A 1 383 ? 28.077  0.128   -3.483  1   32.326  ? 389  ASP A O    1 ? 
ATOM   5813  C  CB   . ASP A 1 383 ? 28.115  -0.112  -0.699  1   32.785  ? 389  ASP A CB   1 ? 
ATOM   5814  C  CG   . ASP A 1 383 ? 27.23   -1.338  -0.518  1   35.45   ? 389  ASP A CG   1 ? 
ATOM   5815  O  OD1  . ASP A 1 383 ? 27.082  -2.082  -1.501  1   34.201  ? 389  ASP A OD1  1 ? 
ATOM   5816  O  OD2  . ASP A 1 383 ? 26.638  -1.49   0.592   1   30.895  ? 389  ASP A OD2  1 ? 
ATOM   5817  H  H    . ASP A 1 383 ? 30.103  1.56    -1.494  1   36.638  ? 389  ASP A H    1 c 
ATOM   5818  H  HA   . ASP A 1 383 ? 29.761  -1.221  -1.194  1   35.829  ? 389  ASP A HA   1 c 
ATOM   5819  H  HB2  . ASP A 1 383 ? 28.382  0.204   0.19    1   34.632  ? 389  ASP A HB2  1 c 
ATOM   5820  H  HB3  . ASP A 1 383 ? 27.586  0.596   -1.122  1   34.619  ? 389  ASP A HB3  1 c 
ATOM   5821  N  N    . THR A 1 384 ? 29.707  -1.415  -3.717  1   31.037  ? 390  THR A N    1 ? 
ATOM   5822  C  CA   . THR A 1 384 ? 29.573  -1.455  -5.16   1   28.925  ? 390  THR A CA   1 ? 
ATOM   5823  C  C    . THR A 1 384 ? 28.163  -1.898  -5.538  1   31.542  ? 390  THR A C    1 ? 
ATOM   5824  O  O    . THR A 1 384 ? 27.578  -1.369  -6.495  1   27.459  ? 390  THR A O    1 ? 
ATOM   5825  C  CB   . THR A 1 384 ? 30.622  -2.397  -5.761  1   31.439  ? 390  THR A CB   1 ? 
ATOM   5826  O  OG1  . THR A 1 384 ? 31.905  -1.894  -5.444  1   27.273  ? 390  THR A OG1  1 ? 
ATOM   5827  C  CG2  . THR A 1 384 ? 30.633  -2.39   -7.283  1   33.751  ? 390  THR A CG2  1 ? 
ATOM   5828  H  H    . THR A 1 384 ? 30.279  -1.996  -3.303  1   30.942  ? 390  THR A H    1 c 
ATOM   5829  H  HA   . THR A 1 384 ? 29.726  -0.551  -5.511  1   30.272  ? 390  THR A HA   1 c 
ATOM   5830  H  HB   . THR A 1 384 ? 30.521  -3.315  -5.412  1   30.507  ? 390  THR A HB   1 c 
ATOM   5831  H  HG1  . THR A 1 384 ? 31.994  -1.08   -5.794  0   26.93   ? 390  THR A HG1  1 c 
ATOM   5832  H  HG21 . THR A 1 384 ? 31.374  -2.931  -7.605  1   33.01   ? 390  THR A HG21 1 c 
ATOM   5833  H  HG22 . THR A 1 384 ? 30.738  -1.477  -7.602  1   33.041  ? 390  THR A HG22 1 c 
ATOM   5834  H  HG23 . THR A 1 384 ? 29.797  -2.756  -7.617  1   33.035  ? 390  THR A HG23 1 c 
ATOM   5835  N  N    . PHE A 1 385 ? 27.622  -2.891  -4.808  1   29.789  ? 391  PHE A N    1 ? 
ATOM   5836  C  CA   . PHE A 1 385 ? 26.279  -3.408  -5.059  1   26.943  ? 391  PHE A CA   1 ? 
ATOM   5837  C  C    . PHE A 1 385 ? 25.286  -2.236  -5.072  1   26.504  ? 391  PHE A C    1 ? 
ATOM   5838  O  O    . PHE A 1 385 ? 24.449  -2.088  -5.982  1   27.394  ? 391  PHE A O    1 ? 
ATOM   5839  C  CB   . PHE A 1 385 ? 25.86   -4.489  -4.05   1   28.467  ? 391  PHE A CB   1 ? 
ATOM   5840  C  CG   . PHE A 1 385 ? 24.461  -5.042  -4.307  1   32.508  ? 391  PHE A CG   1 ? 
ATOM   5841  C  CD1  . PHE A 1 385 ? 24.186  -5.744  -5.478  1   31.229  ? 391  PHE A CD1  1 ? 
ATOM   5842  C  CD2  . PHE A 1 385 ? 23.419  -4.848  -3.401  1   34.262  ? 391  PHE A CD2  1 ? 
ATOM   5843  C  CE1  . PHE A 1 385 ? 22.919  -6.254  -5.741  1   30.609  ? 391  PHE A CE1  1 ? 
ATOM   5844  C  CE2  . PHE A 1 385 ? 22.126  -5.299  -3.705  1   33.072  ? 391  PHE A CE2  1 ? 
ATOM   5845  C  CZ   . PHE A 1 385 ? 21.887  -6.013  -4.854  1   35.52   ? 391  PHE A CZ   1 ? 
ATOM   5846  H  H    . PHE A 1 385 ? 28.113  -3.264  -4.133  1   29.523  ? 391  PHE A H    1 c 
ATOM   5847  H  HA   . PHE A 1 385 ? 26.278  -3.82   -5.963  1   27.686  ? 391  PHE A HA   1 c 
ATOM   5848  H  HB2  . PHE A 1 385 ? 26.508  -5.224  -4.091  1   29.075  ? 391  PHE A HB2  1 c 
ATOM   5849  H  HB3  . PHE A 1 385 ? 25.892  -4.104  -3.146  1   29.048  ? 391  PHE A HB3  1 c 
ATOM   5850  H  HD1  . PHE A 1 385 ? 24.884  -5.902  -6.094  1   31.408  ? 391  PHE A HD1  1 c 
ATOM   5851  H  HD2  . PHE A 1 385 ? 23.568  -4.339  -2.62   1   33.488  ? 391  PHE A HD2  1 c 
ATOM   5852  H  HE1  . PHE A 1 385 ? 22.755  -6.724  -6.543  1   31.86   ? 391  PHE A HE1  1 c 
ATOM   5853  H  HE2  . PHE A 1 385 ? 21.429  -5.17   -3.082  1   33.849  ? 391  PHE A HE2  1 c 
ATOM   5854  H  HZ   . PHE A 1 385 ? 21.024  -6.354  -5.028  1   33.706  ? 391  PHE A HZ   1 c 
ATOM   5855  N  N    . ARG A 1 386 ? 25.426  -1.337  -4.101  1   29.225  ? 392  ARG A N    1 ? 
ATOM   5856  C  CA   . ARG A 1 386 ? 24.464  -0.246  -3.983  1   29.873  ? 392  ARG A CA   1 ? 
ATOM   5857  C  C    . ARG A 1 386 ? 24.713  0.835   -5.044  1   30.381  ? 392  ARG A C    1 ? 
ATOM   5858  O  O    . ARG A 1 386 ? 23.742  1.45    -5.526  1   35.096  ? 392  ARG A O    1 ? 
ATOM   5859  C  CB   . ARG A 1 386 ? 24.4    0.312   -2.561  1   24.105  ? 392  ARG A CB   1 ? 
ATOM   5860  C  CG   . ARG A 1 386 ? 23.814  -0.66   -1.54   1   25.155  ? 392  ARG A CG   1 ? 
ATOM   5861  C  CD   . ARG A 1 386 ? 23.447  -0.078  -0.161  1   25.521  ? 392  ARG A CD   1 ? 
ATOM   5862  N  NE   . ARG A 1 386 ? 22.74   -1.129  0.574   1   29.747  ? 392  ARG A NE   1 ? 
ATOM   5863  C  CZ   . ARG A 1 386 ? 22.377  -1.105  1.852   1   28.543  ? 392  ARG A CZ   1 ? 
ATOM   5864  N  NH1  . ARG A 1 386 ? 22.664  -0.105  2.673   1   30.094  ? 392  ARG A NH1  1 ? 
ATOM   5865  N  NH2  . ARG A 1 386 ? 21.672  -2.104  2.314   1   31.259  ? 392  ARG A NH2  1 ? 
ATOM   5866  H  H    . ARG A 1 386 ? 26.114  -1.398  -3.502  1   28.668  ? 392  ARG A H    1 c 
ATOM   5867  H  HA   . ARG A 1 386 ? 23.566  -0.626  -4.162  1   28.616  ? 392  ARG A HA   1 c 
ATOM   5868  H  HB2  . ARG A 1 386 ? 25.306  0.559   -2.278  1   25.564  ? 392  ARG A HB2  1 c 
ATOM   5869  H  HB3  . ARG A 1 386 ? 23.856  1.129   -2.567  1   25.582  ? 392  ARG A HB3  1 c 
ATOM   5870  H  HG2  . ARG A 1 386 ? 23.008  -1.065  -1.928  1   25.053  ? 392  ARG A HG2  1 c 
ATOM   5871  H  HG3  . ARG A 1 386 ? 24.456  -1.391  -1.404  1   25.08   ? 392  ARG A HG3  1 c 
ATOM   5872  H  HD2  . ARG A 1 386 ? 24.253  0.184   0.329   1   26.402  ? 392  ARG A HD2  1 c 
ATOM   5873  H  HD3  . ARG A 1 386 ? 22.866  0.704   -0.26   1   26.387  ? 392  ARG A HD3  1 c 
ATOM   5874  H  HE   . ARG A 1 386 ? 22.535  -1.852  0.133   1   28.403  ? 392  ARG A HE   1 c 
ATOM   5875  H  HH11 . ARG A 1 386 ? 23.102  0.603   2.376   1   29.557  ? 392  ARG A HH11 1 c 
ATOM   5876  H  HH12 . ARG A 1 386 ? 22.414  -0.148  3.52    1   29.613  ? 392  ARG A HH12 1 c 
ATOM   5877  H  HH21 . ARG A 1 386 ? 21.021  -2.448  1.823   1   30.351  ? 392  ARG A HH21 1 c 
ATOM   5878  H  HH22 . ARG A 1 386 ? 21.845  -2.428  3.118   1   30.348  ? 392  ARG A HH22 1 c 
ATOM   5879  N  N    . SER A 1 387 ? 25.979  1.039   -5.447  1   31.118  ? 393  SER A N    1 ? 
ATOM   5880  C  CA   . SER A 1 387 ? 26.263  1.988   -6.524  1   33.548  ? 393  SER A CA   1 ? 
ATOM   5881  C  C    . SER A 1 387 ? 25.566  1.489   -7.783  1   32.342  ? 393  SER A C    1 ? 
ATOM   5882  O  O    . SER A 1 387 ? 24.794  2.203   -8.373  1   31.703  ? 393  SER A O    1 ? 
ATOM   5883  C  CB   . SER A 1 387 ? 27.739  2.234   -6.817  1   26.74   ? 393  SER A CB   1 ? 
ATOM   5884  O  OG   . SER A 1 387 ? 28.468  2.54    -5.642  1   26.144  ? 393  SER A OG   1 ? 
ATOM   5885  H  H    . SER A 1 387 ? 26.67   0.594   -5.048  1   31.438  ? 393  SER A H    1 c 
ATOM   5886  H  HA   . SER A 1 387 ? 25.854  2.856   -6.275  1   31.508  ? 393  SER A HA   1 c 
ATOM   5887  H  HB2  . SER A 1 387 ? 28.121  1.437   -7.233  1   28.065  ? 393  SER A HB2  1 c 
ATOM   5888  H  HB3  . SER A 1 387 ? 27.822  2.973   -7.45   1   28.005  ? 393  SER A HB3  1 c 
ATOM   5889  H  HG   . SER A 1 387 ? 29.265  2.674   -5.852  0   26.52   ? 393  SER A HG   1 c 
ATOM   5890  N  N    . LEU A 1 388 ? 25.867  0.252   -8.167  1   33.478  ? 394  LEU A N    1 ? 
ATOM   5891  C  CA   . LEU A 1 388 ? 25.316  -0.381  -9.34   1   32.669  ? 394  LEU A CA   1 ? 
ATOM   5892  C  C    . LEU A 1 388 ? 23.786  -0.471  -9.312  1   35.648  ? 394  LEU A C    1 ? 
ATOM   5893  O  O    . LEU A 1 388 ? 23.152  -0.276  -10.367 1   29.84   ? 394  LEU A O    1 ? 
ATOM   5894  C  CB   . LEU A 1 388 ? 25.932  -1.775  -9.463  1   36.413  ? 394  LEU A CB   1 ? 
ATOM   5895  C  CG   . LEU A 1 388 ? 27.404  -1.842  -9.867  1   36.096  ? 394  LEU A CG   1 ? 
ATOM   5896  C  CD1  . LEU A 1 388 ? 27.822  -3.316  -9.935  1   34.516  ? 394  LEU A CD1  1 ? 
ATOM   5897  C  CD2  . LEU A 1 388 ? 27.651  -1.19   -11.197 1   34.097  ? 394  LEU A CD2  1 ? 
ATOM   5898  H  H    . LEU A 1 388 ? 26.461  -0.224  -7.661  1   32.992  ? 394  LEU A H    1 c 
ATOM   5899  H  HA   . LEU A 1 388 ? 25.576  0.158   -10.128 1   34.024  ? 394  LEU A HA   1 c 
ATOM   5900  H  HB2  . LEU A 1 388 ? 25.825  -2.235  -8.599  1   35.419  ? 394  LEU A HB2  1 c 
ATOM   5901  H  HB3  . LEU A 1 388 ? 25.411  -2.278  -10.128 1   35.367  ? 394  LEU A HB3  1 c 
ATOM   5902  H  HG   . LEU A 1 388 ? 27.948  -1.384  -9.175  1   35.432  ? 394  LEU A HG   1 c 
ATOM   5903  H  HD11 . LEU A 1 388 ? 27.64   -3.745  -9.082  1   34.964  ? 394  LEU A HD11 1 c 
ATOM   5904  H  HD12 . LEU A 1 388 ? 28.772  -3.375  -10.132 1   34.964  ? 394  LEU A HD12 1 c 
ATOM   5905  H  HD13 . LEU A 1 388 ? 27.319  -3.763  -10.636 1   34.941  ? 394  LEU A HD13 1 c 
ATOM   5906  H  HD21 . LEU A 1 388 ? 27.546  -0.227  -11.114 1   34.666  ? 394  LEU A HD21 1 c 
ATOM   5907  H  HD22 . LEU A 1 388 ? 27.015  -1.529  -11.849 1   34.678  ? 394  LEU A HD22 1 c 
ATOM   5908  H  HD23 . LEU A 1 388 ? 28.555  -1.39   -11.494 1   34.677  ? 394  LEU A HD23 1 c 
ATOM   5909  N  N    . GLN A 1 389 ? 23.195  -0.835  -8.161  1   33.275  ? 395  GLN A N    1 ? 
ATOM   5910  C  CA   . GLN A 1 389 ? 21.742  -0.941  -8.072  1   35.021  ? 395  GLN A CA   1 ? 
ATOM   5911  C  C    . GLN A 1 389 ? 21.111  0.459   -8.12   1   33.69   ? 395  GLN A C    1 ? 
ATOM   5912  O  O    . GLN A 1 389 ? 19.982  0.644   -8.597  1   34.342  ? 395  GLN A O    1 ? 
ATOM   5913  C  CB   . GLN A 1 389 ? 21.222  -1.675  -6.825  1   33.234  ? 395  GLN A CB   1 ? 
ATOM   5914  C  CG   . GLN A 1 389 ? 21.576  -3.156  -6.822  1   31.758  ? 395  GLN A CG   1 ? 
ATOM   5915  C  CD   . GLN A 1 389 ? 20.517  -3.963  -7.532  1   32.521  ? 395  GLN A CD   1 ? 
ATOM   5916  O  OE1  . GLN A 1 389 ? 19.333  -3.888  -7.168  1   34.996  ? 395  GLN A OE1  1 ? 
ATOM   5917  N  NE2  . GLN A 1 389 ? 20.911  -4.649  -8.608  1   34.763  ? 395  GLN A NE2  1 ? 
ATOM   5918  H  H    . GLN A 1 389 ? 23.703  -1.023  -7.425  1   34.202  ? 395  GLN A H    1 c 
ATOM   5919  H  HA   . GLN A 1 389 ? 21.426  -1.446  -8.864  1   34.083  ? 395  GLN A HA   1 c 
ATOM   5920  H  HB2  . GLN A 1 389 ? 21.602  -1.253  -6.026  1   33.294  ? 395  GLN A HB2  1 c 
ATOM   5921  H  HB3  . GLN A 1 389 ? 20.252  -1.579  -6.782  1   33.342  ? 395  GLN A HB3  1 c 
ATOM   5922  H  HG2  . GLN A 1 389 ? 22.442  -3.288  -7.263  1   32.276  ? 395  GLN A HG2  1 c 
ATOM   5923  H  HG3  . GLN A 1 389 ? 21.657  -3.471  -5.897  1   32.282  ? 395  GLN A HG3  1 c 
ATOM   5924  H  HE21 . GLN A 1 389 ? 20.31   -5.08   -9.098  1   34.049  ? 395  GLN A HE21 1 c 
ATOM   5925  H  HE22 . GLN A 1 389 ? 21.768  -4.678  -8.833  1   33.993  ? 395  GLN A HE22 1 c 
ATOM   5926  N  N    . SER A 1 390 ? 21.831  1.474   -7.656  1   30.824  ? 396  SER A N    1 ? 
ATOM   5927  C  CA   . SER A 1 390 ? 21.301  2.822   -7.79   1   29.234  ? 396  SER A CA   1 ? 
ATOM   5928  C  C    . SER A 1 390 ? 21.307  3.257   -9.267  1   34.403  ? 396  SER A C    1 ? 
ATOM   5929  O  O    . SER A 1 390 ? 20.398  3.984   -9.705  1   39.435  ? 396  SER A O    1 ? 
ATOM   5930  C  CB   . SER A 1 390 ? 22.049  3.78    -6.924  1   27.322  ? 396  SER A CB   1 ? 
ATOM   5931  O  OG   . SER A 1 390 ? 22.035  3.384   -5.561  1   32.425  ? 396  SER A OG   1 ? 
ATOM   5932  H  H    . SER A 1 390 ? 22.638  1.338   -7.251  1   31.128  ? 396  SER A H    1 c 
ATOM   5933  H  HA   . SER A 1 390 ? 20.359  2.81    -7.482  1   30.077  ? 396  SER A HA   1 c 
ATOM   5934  H  HB2  . SER A 1 390 ? 22.971  3.837   -7.235  1   28.951  ? 396  SER A HB2  1 c 
ATOM   5935  H  HB3  . SER A 1 390 ? 21.648  4.667   -7.006  1   28.91   ? 396  SER A HB3  1 c 
ATOM   5936  H  HG   . SER A 1 390 ? 22.472  3.954   -5.114  0   32.48   ? 396  SER A HG   1 c 
ATOM   5937  N  N    . ILE A 1 391 ? 22.329  2.851   -10.043 1   32.434  ? 397  ILE A N    1 ? 
ATOM   5938  C  CA   . ILE A 1 391 ? 22.35   3.128   -11.481 1   31.45   ? 397  ILE A CA   1 ? 
ATOM   5939  C  C    . ILE A 1 391 ? 21.122  2.44    -12.107 1   34.947  ? 397  ILE A C    1 ? 
ATOM   5940  O  O    . ILE A 1 391 ? 20.395  3.031   -12.919 1   35.999  ? 397  ILE A O    1 ? 
ATOM   5941  C  CB   . ILE A 1 391 ? 23.692  2.683   -12.121 1   30.995  ? 397  ILE A CB   1 ? 
ATOM   5942  C  CG1  . ILE A 1 391 ? 24.84   3.615   -11.758 1   37      ? 397  ILE A CG1  1 ? 
ATOM   5943  C  CG2  . ILE A 1 391 ? 23.582  2.581   -13.635 1   32.072  ? 397  ILE A CG2  1 ? 
ATOM   5944  C  CD1  . ILE A 1 391 ? 26.227  2.973   -11.755 1   34.026  ? 397  ILE A CD1  1 ? 
ATOM   5945  H  H    . ILE A 1 391 ? 23.031  2.4     -9.669  1   32.619  ? 397  ILE A H    1 c 
ATOM   5946  H  HA   . ILE A 1 391 ? 22.259  4.093   -11.606 1   32.205  ? 397  ILE A HA   1 c 
ATOM   5947  H  HB   . ILE A 1 391 ? 23.909  1.796   -11.775 1   32.335  ? 397  ILE A HB   1 c 
ATOM   5948  H  HG12 . ILE A 1 391 ? 24.846  4.363   -12.39  1   34.834  ? 397  ILE A HG12 1 c 
ATOM   5949  H  HG13 . ILE A 1 391 ? 24.669  3.984   -10.867 1   34.821  ? 397  ILE A HG13 1 c 
ATOM   5950  H  HG21 . ILE A 1 391 ? 24.471  2.512   -14.023 1   31.859  ? 397  ILE A HG21 1 c 
ATOM   5951  H  HG22 . ILE A 1 391 ? 23.139  3.373   -13.985 1   31.807  ? 397  ILE A HG22 1 c 
ATOM   5952  H  HG23 . ILE A 1 391 ? 23.067  1.791   -13.873 1   31.87   ? 397  ILE A HG23 1 c 
ATOM   5953  H  HD11 . ILE A 1 391 ? 26.251  2.248   -11.102 1   34.867  ? 397  ILE A HD11 1 c 
ATOM   5954  H  HD12 . ILE A 1 391 ? 26.897  3.642   -11.52  1   34.867  ? 397  ILE A HD12 1 c 
ATOM   5955  H  HD13 . ILE A 1 391 ? 26.424  2.615   -12.642 1   34.851  ? 397  ILE A HD13 1 c 
ATOM   5956  N  N    . LEU A 1 392 ? 20.861  1.188   -11.696 1   29.437  ? 398  LEU A N    1 ? 
ATOM   5957  C  CA   . LEU A 1 392 ? 19.806  0.404   -12.318 1   32.391  ? 398  LEU A CA   1 ? 
ATOM   5958  C  C    . LEU A 1 392 ? 18.433  1.03    -12.091 1   37.444  ? 398  LEU A C    1 ? 
ATOM   5959  O  O    . LEU A 1 392 ? 17.68   1.134   -13.057 1   38.84   ? 398  LEU A O    1 ? 
ATOM   5960  C  CB   . LEU A 1 392 ? 19.837  -1.049  -11.864 1   31.577  ? 398  LEU A CB   1 ? 
ATOM   5961  C  CG   . LEU A 1 392 ? 18.915  -2.034  -12.579 1   33.193  ? 398  LEU A CG   1 ? 
ATOM   5962  C  CD1  . LEU A 1 392 ? 19.105  -2.174  -14.065 1   35.54   ? 398  LEU A CD1  1 ? 
ATOM   5963  C  CD2  . LEU A 1 392 ? 19.129  -3.42   -11.938 1   36.234  ? 398  LEU A CD2  1 ? 
ATOM   5964  H  H    . LEU A 1 392 ? 21.354  0.815   -11.022 1   31.356  ? 398  LEU A H    1 c 
ATOM   5965  H  HA   . LEU A 1 392 ? 19.973  0.421   -13.295 1   32.671  ? 398  LEU A HA   1 c 
ATOM   5966  H  HB2  . LEU A 1 392 ? 20.762  -1.374  -11.954 1   32.125  ? 398  LEU A HB2  1 c 
ATOM   5967  H  HB3  . LEU A 1 392 ? 19.621  -1.07   -10.903 1   32.125  ? 398  LEU A HB3  1 c 
ATOM   5968  H  HG   . LEU A 1 392 ? 17.976  -1.76   -12.412 1   33.869  ? 398  LEU A HG   1 c 
ATOM   5969  H  HD11 . LEU A 1 392 ? 18.918  -1.324  -14.498 1   34.809  ? 398  LEU A HD11 1 c 
ATOM   5970  H  HD12 . LEU A 1 392 ? 18.499  -2.851  -14.409 1   34.823  ? 398  LEU A HD12 1 c 
ATOM   5971  H  HD13 . LEU A 1 392 ? 20.022  -2.436  -14.253 1   34.82   ? 398  LEU A HD13 1 c 
ATOM   5972  H  HD21 . LEU A 1 392 ? 18.902  -3.38   -10.994 1   35.319  ? 398  LEU A HD21 1 c 
ATOM   5973  H  HD22 . LEU A 1 392 ? 20.06   -3.683  -12.036 1   35.319  ? 398  LEU A HD22 1 c 
ATOM   5974  H  HD23 . LEU A 1 392 ? 18.561  -4.074  -12.379 1   35.318  ? 398  LEU A HD23 1 c 
ATOM   5975  N  N    . TRP A 1 393 ? 18.129  1.496   -10.866 1   33.559  ? 399  TRP A N    1 ? 
ATOM   5976  C  CA   . TRP A 1 393 ? 16.75   1.769   -10.487 1   38.098  ? 399  TRP A CA   1 ? 
ATOM   5977  C  C    . TRP A 1 393 ? 16.506  3.243   -10.213 1   34.325  ? 399  TRP A C    1 ? 
ATOM   5978  O  O    . TRP A 1 393 ? 15.367  3.626   -10.036 1   35.153  ? 399  TRP A O    1 ? 
ATOM   5979  C  CB   . TRP A 1 393 ? 16.296  0.949   -9.266  1   37.999  ? 399  TRP A CB   1 ? 
ATOM   5980  C  CG   . TRP A 1 393 ? 16.017  -0.5    -9.581  1   35.605  ? 399  TRP A CG   1 ? 
ATOM   5981  C  CD1  . TRP A 1 393 ? 16.84   -1.538  -9.28   1   34.998  ? 399  TRP A CD1  1 ? 
ATOM   5982  C  CD2  . TRP A 1 393 ? 14.927  -1.063  -10.342 1   37.593  ? 399  TRP A CD2  1 ? 
ATOM   5983  N  NE1  . TRP A 1 393 ? 16.306  -2.7    -9.728  1   33.369  ? 399  TRP A NE1  1 ? 
ATOM   5984  C  CE2  . TRP A 1 393 ? 15.142  -2.454  -10.381 1   34.081  ? 399  TRP A CE2  1 ? 
ATOM   5985  C  CE3  . TRP A 1 393 ? 13.783  -0.541  -10.959 1   39.52   ? 399  TRP A CE3  1 ? 
ATOM   5986  C  CZ2  . TRP A 1 393 ? 14.279  -3.329  -11.028 1   38.542  ? 399  TRP A CZ2  1 ? 
ATOM   5987  C  CZ3  . TRP A 1 393 ? 12.936  -1.402  -11.621 1   41.421  ? 399  TRP A CZ3  1 ? 
ATOM   5988  C  CH2  . TRP A 1 393 ? 13.2    -2.771  -11.68  1   43.04   ? 399  TRP A CH2  1 ? 
ATOM   5989  H  H    . TRP A 1 393 ? 18.793  1.63    -10.253 1   35.38   ? 399  TRP A H    1 c 
ATOM   5990  H  HA   . TRP A 1 393 ? 16.169  1.505   -11.249 1   36.489  ? 399  TRP A HA   1 c 
ATOM   5991  H  HB2  . TRP A 1 393 ? 16.996  0.996   -8.581  1   37.449  ? 399  TRP A HB2  1 c 
ATOM   5992  H  HB3  . TRP A 1 393 ? 15.482  1.355   -8.898  1   37.422  ? 399  TRP A HB3  1 c 
ATOM   5993  H  HD1  . TRP A 1 393 ? 17.635  -1.476  -8.776  1   34.789  ? 399  TRP A HD1  1 c 
ATOM   5994  H  HE1  . TRP A 1 393 ? 16.664  -3.489  -9.62   1   33.986  ? 399  TRP A HE1  1 c 
ATOM   5995  H  HE3  . TRP A 1 393 ? 13.614  0.385   -10.947 1   39.469  ? 399  TRP A HE3  1 c 
ATOM   5996  H  HZ2  . TRP A 1 393 ? 14.461  -4.252  -11.074 1   38.442  ? 399  TRP A HZ2  1 c 
ATOM   5997  H  HZ3  . TRP A 1 393 ? 12.169  -1.06   -12.049 1   41.323  ? 399  TRP A HZ3  1 c 
ATOM   5998  H  HH2  . TRP A 1 393 ? 12.585  -3.338  -12.111 1   41.452  ? 399  TRP A HH2  1 c 
ATOM   5999  N  N    . ASN A 1 394 ? 17.542  4.079   -10.239 1   32.535  ? 400  ASN A N    1 ? 
ATOM   6000  C  CA   . ASN A 1 394 ? 17.332  5.479   -9.914  1   33.804  ? 400  ASN A CA   1 ? 
ATOM   6001  C  C    . ASN A 1 394 ? 16.338  6.163   -10.864 1   32.904  ? 400  ASN A C    1 ? 
ATOM   6002  O  O    . ASN A 1 394 ? 15.604  7.048   -10.438 1   39.615  ? 400  ASN A O    1 ? 
ATOM   6003  C  CB   . ASN A 1 394 ? 18.653  6.219   -9.765  1   34.293  ? 400  ASN A CB   1 ? 
ATOM   6004  C  CG   . ASN A 1 394 ? 19.16   6.197   -8.361  1   31.635  ? 400  ASN A CG   1 ? 
ATOM   6005  O  OD1  . ASN A 1 394 ? 18.601  5.52    -7.498  1   29.405  ? 400  ASN A OD1  1 ? 
ATOM   6006  N  ND2  . ASN A 1 394 ? 20.113  7.064   -8.064  1   36.278  ? 400  ASN A ND2  1 ? 
ATOM   6007  H  H    . ASN A 1 394 ? 18.378  3.787   -10.462 1   33.296  ? 400  ASN A H    1 c 
ATOM   6008  H  HA   . ASN A 1 394 ? 16.907  5.498   -9.027  1   33.482  ? 400  ASN A HA   1 c 
ATOM   6009  H  HB2  . ASN A 1 394 ? 19.318  5.818   -10.357 1   33.581  ? 400  ASN A HB2  1 c 
ATOM   6010  H  HB3  . ASN A 1 394 ? 18.529  7.149   -10.041 1   33.556  ? 400  ASN A HB3  1 c 
ATOM   6011  H  HD21 . ASN A 1 394 ? 20.439  7.095   -7.239  1   34.766  ? 400  ASN A HD21 1 c 
ATOM   6012  H  HD22 . ASN A 1 394 ? 20.425  7.614   -8.686  1   34.764  ? 400  ASN A HD22 1 c 
ATOM   6013  N  N    . GLY A 1 395 ? 16.285  5.768   -12.133 1   37.532  ? 401  GLY A N    1 ? 
ATOM   6014  C  CA   . GLY A 1 395 ? 15.394  6.381   -13.111 1   38.495  ? 401  GLY A CA   1 ? 
ATOM   6015  C  C    . GLY A 1 395 ? 13.917  6.174   -12.781 1   38.468  ? 401  GLY A C    1 ? 
ATOM   6016  O  O    . GLY A 1 395 ? 13.126  7.114   -12.859 1   41.378  ? 401  GLY A O    1 ? 
ATOM   6017  H  H    . GLY A 1 395 ? 16.834  5.092   -12.41  1   36.52   ? 401  GLY A H    1 c 
ATOM   6018  H  HA2  . GLY A 1 395 ? 15.586  7.347   -13.153 1   38.258  ? 401  GLY A HA2  1 c 
ATOM   6019  H  HA3  . GLY A 1 395 ? 15.586  5.998   -13.999 1   38.258  ? 401  GLY A HA3  1 c 
ATOM   6020  N  N    . GLU A 1 396 ? 13.556  4.957   -12.371 1   32.081  ? 402  GLU A N    1 ? 
ATOM   6021  C  CA   . GLU A 1 396 ? 12.245  4.711   -11.803 1   34.78   ? 402  GLU A CA   1 ? 
ATOM   6022  C  C    . GLU A 1 396 ? 11.971  5.545   -10.54  1   38.378  ? 402  GLU A C    1 ? 
ATOM   6023  O  O    . GLU A 1 396 ? 10.891  6.114   -10.428 1   36.392  ? 402  GLU A O    1 ? 
ATOM   6024  C  CB   . GLU A 1 396 ? 12.125  3.213   -11.567 1   34.168  ? 402  GLU A CB   1 ? 
ATOM   6025  C  CG   . GLU A 1 396 ? 11.946  2.439   -12.865 1   40.303  ? 402  GLU A CG   1 ? 
ATOM   6026  C  CD   . GLU A 1 396 ? 10.635  2.733   -13.586 1   51.338  ? 402  GLU A CD   1 ? 
ATOM   6027  O  OE1  . GLU A 1 396 ? 9.641   1.99    -13.387 1   52.68   ? 402  GLU A OE1  1 ? 
ATOM   6028  O  OE2  . GLU A 1 396 ? 10.637  3.66    -14.419 1   62.666  ? 402  GLU A OE2  1 ? 
ATOM   6029  H  H    . GLU A 1 396 ? 14.143  4.261   -12.454 1   34.25   ? 402  GLU A H    1 c 
ATOM   6030  H  HA   . GLU A 1 396 ? 11.572  4.968   -12.48  1   34.999  ? 402  GLU A HA   1 c 
ATOM   6031  H  HB2  . GLU A 1 396 ? 12.926  2.896   -11.1   1   35.615  ? 402  GLU A HB2  1 c 
ATOM   6032  H  HB3  . GLU A 1 396 ? 11.354  3.045   -10.989 1   35.662  ? 402  GLU A HB3  1 c 
ATOM   6033  H  HG2  . GLU A 1 396 ? 12.688  2.651   -13.47  1   40.932  ? 402  GLU A HG2  1 c 
ATOM   6034  H  HG3  . GLU A 1 396 ? 11.986  1.478   -12.672 1   41.011  ? 402  GLU A HG3  1 c 
ATOM   6035  N  N    . LEU A 1 397 ? 12.924  5.631   -9.58   1   39.874  ? 403  LEU A N    1 ? 
ATOM   6036  C  CA   . LEU A 1 397 ? 12.772  6.502   -8.411  1   35.416  ? 403  LEU A CA   1 ? 
ATOM   6037  C  C    . LEU A 1 397 ? 12.495  7.952   -8.833  1   37.277  ? 403  LEU A C    1 ? 
ATOM   6038  O  O    . LEU A 1 397 ? 11.675  8.61    -8.191  1   33.546  ? 403  LEU A O    1 ? 
ATOM   6039  C  CB   . LEU A 1 397 ? 13.998  6.435   -7.499  1   36.061  ? 403  LEU A CB   1 ? 
ATOM   6040  C  CG   . LEU A 1 397 ? 14.064  7.415   -6.32   1   36.217  ? 403  LEU A CG   1 ? 
ATOM   6041  C  CD1  . LEU A 1 397 ? 12.882  7.314   -5.405  1   40.001  ? 403  LEU A CD1  1 ? 
ATOM   6042  C  CD2  . LEU A 1 397 ? 15.337  7.168   -5.522  1   36.347  ? 403  LEU A CD2  1 ? 
ATOM   6043  H  H    . LEU A 1 397 ? 13.685  5.132   -9.661  1   38.419  ? 403  LEU A H    1 c 
ATOM   6044  H  HA   . LEU A 1 397 ? 11.985  6.182   -7.902  1   36.703  ? 403  LEU A HA   1 c 
ATOM   6045  H  HB2  . LEU A 1 397 ? 14.058  5.52    -7.14   1   35.951  ? 403  LEU A HB2  1 c 
ATOM   6046  H  HB3  . LEU A 1 397 ? 14.799  6.572   -8.055  1   35.967  ? 403  LEU A HB3  1 c 
ATOM   6047  H  HG   . LEU A 1 397 ? 14.101  8.338   -6.681  1   36.901  ? 403  LEU A HG   1 c 
ATOM   6048  H  HD11 . LEU A 1 397 ? 12.073  7.548   -5.889  1   38.761  ? 403  LEU A HD11 1 c 
ATOM   6049  H  HD12 . LEU A 1 397 ? 12.998  7.924   -4.657  1   38.799  ? 403  LEU A HD12 1 c 
ATOM   6050  H  HD13 . LEU A 1 397 ? 12.806  6.405   -5.071  1   38.741  ? 403  LEU A HD13 1 c 
ATOM   6051  H  HD21 . LEU A 1 397 ? 16.109  7.242   -6.109  1   36.325  ? 403  LEU A HD21 1 c 
ATOM   6052  H  HD22 . LEU A 1 397 ? 15.31   6.278   -5.136  1   36.265  ? 403  LEU A HD22 1 c 
ATOM   6053  H  HD23 . LEU A 1 397 ? 15.408  7.827   -4.811  1   36.303  ? 403  LEU A HD23 1 c 
ATOM   6054  N  N    . GLU A 1 398 ? 13.175  8.438   -9.895  1   35.004  ? 404  GLU A N    1 ? 
ATOM   6055  C  CA   . GLU A 1 398 ? 13.093  9.831   -10.307 1   45.271  ? 404  GLU A CA   1 ? 
ATOM   6056  C  C    . GLU A 1 398 ? 11.667  10.18   -10.759 1   37.339  ? 404  GLU A C    1 ? 
ATOM   6057  O  O    . GLU A 1 398 ? 11.265  11.324  -10.613 1   35.616  ? 404  GLU A O    1 ? 
ATOM   6058  C  CB   . GLU A 1 398 ? 14.096  10.233  -11.406 1   46.255  ? 404  GLU A CB   1 ? 
ATOM   6059  C  CG   . GLU A 1 398 ? 13.727  11.554  -12.09  1   64.195  ? 404  GLU A CG   1 ? 
ATOM   6060  C  CD   . GLU A 1 398 ? 14.766  12.275  -12.953 1   82.366  ? 404  GLU A CD   1 ? 
ATOM   6061  O  OE1  . GLU A 1 398 ? 14.351  13.026  -13.875 1   88.155  ? 404  GLU A OE1  1 ? 
ATOM   6062  O  OE2  . GLU A 1 398 ? 15.981  12.136  -12.699 1   75.16   ? 404  GLU A OE2  1 ? 
ATOM   6063  H  H    . GLU A 1 398 ? 13.714  7.875   -10.372 1   37.718  ? 404  GLU A H    1 c 
ATOM   6064  H  HA   . GLU A 1 398 ? 13.299  10.387  -9.513  1   41.726  ? 404  GLU A HA   1 c 
ATOM   6065  H  HB2  . GLU A 1 398 ? 14.988  10.312  -11.007 1   49.704  ? 404  GLU A HB2  1 c 
ATOM   6066  H  HB3  . GLU A 1 398 ? 14.131  9.52    -12.078 1   49.583  ? 404  GLU A HB3  1 c 
ATOM   6067  H  HG2  . GLU A 1 398 ? 12.942  11.394  -12.655 1   62.622  ? 404  GLU A HG2  1 c 
ATOM   6068  H  HG3  . GLU A 1 398 ? 13.442  12.184  -11.395 1   62.617  ? 404  GLU A HG3  1 c 
ATOM   6069  N  N    . LYS A 1 399 ? 10.962  9.217   -11.354 1   34.816  ? 405  LYS A N    1 ? 
ATOM   6070  C  CA   . LYS A 1 399 ? 9.595   9.364   -11.836 1   42.997  ? 405  LYS A CA   1 ? 
ATOM   6071  C  C    . LYS A 1 399 ? 8.512   9.062   -10.783 1   39.853  ? 405  LYS A C    1 ? 
ATOM   6072  O  O    . LYS A 1 399 ? 7.367   9.408   -10.996 1   44.951  ? 405  LYS A O    1 ? 
ATOM   6073  C  CB   . LYS A 1 399 ? 9.372   8.395   -12.999 1   47.998  ? 405  LYS A CB   1 ? 
ATOM   6074  C  CG   . LYS A 1 399 ? 10.006  8.865   -14.285 1   51.14   ? 405  LYS A CG   1 ? 
ATOM   6075  C  CD   . LYS A 1 399 ? 9.911   7.918   -15.469 1   58.478  ? 405  LYS A CD   1 ? 
ATOM   6076  C  CE   . LYS A 1 399 ? 10.795  8.484   -16.56  1   72.566  ? 405  LYS A CE   1 ? 
ATOM   6077  N  NZ   . LYS A 1 399 ? 10.379  8.119   -17.918 1   78.927  ? 405  LYS A NZ   1 ? 
ATOM   6078  H  H    . LYS A 1 399 ? 11.368  8.407   -11.474 1   37.315  ? 405  LYS A H    1 c 
ATOM   6079  H  HA   . LYS A 1 399 ? 9.473   10.292  -12.162 1   41.463  ? 405  LYS A HA   1 c 
ATOM   6080  H  HB2  . LYS A 1 399 ? 9.745   7.518   -12.766 1   47.417  ? 405  LYS A HB2  1 c 
ATOM   6081  H  HB3  . LYS A 1 399 ? 8.409   8.284   -13.148 1   47.435  ? 405  LYS A HB3  1 c 
ATOM   6082  H  HG2  . LYS A 1 399 ? 9.589   9.719   -14.534 1   52.088  ? 405  LYS A HG2  1 c 
ATOM   6083  H  HG3  . LYS A 1 399 ? 10.954  9.049   -14.106 1   52.083  ? 405  LYS A HG3  1 c 
ATOM   6084  H  HD2  . LYS A 1 399 ? 10.229  7.024   -15.215 1   59.625  ? 405  LYS A HD2  1 c 
ATOM   6085  H  HD3  . LYS A 1 399 ? 8.984   7.862   -15.786 1   59.703  ? 405  LYS A HD3  1 c 
ATOM   6086  H  HE2  . LYS A 1 399 ? 10.804  9.458   -16.496 1   70.212  ? 405  LYS A HE2  1 c 
ATOM   6087  H  HE3  . LYS A 1 399 ? 11.708  8.172   -16.42  1   70.426  ? 405  LYS A HE3  1 c 
ATOM   6088  H  HZ1  . LYS A 1 399 ? 9.513   8.354   -18.049 1   76.781  ? 405  LYS A HZ1  1 c 
ATOM   6089  H  HZ2  . LYS A 1 399 ? 10.463  7.222   -18.032 1   76.882  ? 405  LYS A HZ2  1 c 
ATOM   6090  H  HZ3  . LYS A 1 399 ? 10.898  8.545   -18.526 1   76.884  ? 405  LYS A HZ3  1 c 
ATOM   6091  N  N    . THR A 1 400 ? 8.846   8.454   -9.648  1   35.508  ? 406  THR A N    1 ? 
ATOM   6092  C  CA   . THR A 1 400 ? 7.835   8.019   -8.7    1   39.372  ? 406  THR A CA   1 ? 
ATOM   6093  C  C    . THR A 1 400 ? 7.205   9.217   -7.968  1   39.411  ? 406  THR A C    1 ? 
ATOM   6094  O  O    . THR A 1 400 ? 7.886   10.128  -7.533  1   35.807  ? 406  THR A O    1 ? 
ATOM   6095  C  CB   . THR A 1 400 ? 8.497   7.046   -7.737  1   42.822  ? 406  THR A CB   1 ? 
ATOM   6096  O  OG1  . THR A 1 400 ? 9.039   6.033   -8.578  1   43.972  ? 406  THR A OG1  1 ? 
ATOM   6097  C  CG2  . THR A 1 400 ? 7.529   6.482   -6.714  1   43.951  ? 406  THR A CG2  1 ? 
ATOM   6098  H  H    . THR A 1 400 ? 9.727   8.306   -9.455  1   37.412  ? 406  THR A H    1 c 
ATOM   6099  H  HA   . THR A 1 400 ? 7.133   7.541   -9.193  1   39.23   ? 406  THR A HA   1 c 
ATOM   6100  H  HB   . THR A 1 400 ? 9.233   7.503   -7.263  1   42.559  ? 406  THR A HB   1 c 
ATOM   6101  H  HG1  . THR A 1 400 ? 8.424   5.648   -9.016  0   44.01   ? 406  THR A HG1  1 c 
ATOM   6102  H  HG21 . THR A 1 400 ? 7.978   5.801   -6.185  1   43.608  ? 406  THR A HG21 1 c 
ATOM   6103  H  HG22 . THR A 1 400 ? 6.768   6.086   -7.171  1   43.608  ? 406  THR A HG22 1 c 
ATOM   6104  H  HG23 . THR A 1 400 ? 7.221   7.193   -6.128  1   43.591  ? 406  THR A HG23 1 c 
ATOM   6105  N  N    . THR A 1 401 ? 5.877   9.228   -7.838  1   39.619  ? 407  THR A N    1 ? 
ATOM   6106  C  CA   . THR A 1 401 ? 5.177   10.314  -7.154  1   39.49   ? 407  THR A CA   1 ? 
ATOM   6107  C  C    . THR A 1 401 ? 5.47    10.209  -5.66   1   36.874  ? 407  THR A C    1 ? 
ATOM   6108  O  O    . THR A 1 401 ? 5.342   9.126   -5.086  1   33.334  ? 407  THR A O    1 ? 
ATOM   6109  C  CB   . THR A 1 401 ? 3.666   10.221  -7.39   1   44.144  ? 407  THR A CB   1 ? 
ATOM   6110  O  OG1  . THR A 1 401 ? 3.352   10.056  -8.765  1   42.103  ? 407  THR A OG1  1 ? 
ATOM   6111  C  CG2  . THR A 1 401 ? 2.918   11.433  -6.855  1   41.407  ? 407  THR A CG2  1 ? 
ATOM   6112  H  H    . THR A 1 401 ? 5.387   8.538   -8.183  1   39.566  ? 407  THR A H    1 c 
ATOM   6113  H  HA   . THR A 1 401 ? 5.506   11.174  -7.496  1   39.746  ? 407  THR A HA   1 c 
ATOM   6114  H  HB   . THR A 1 401 ? 3.328   9.435   -6.899  1   42.303  ? 407  THR A HB   1 c 
ATOM   6115  H  HG1  . THR A 1 401 ? 3.663   10.71   -9.22   0   40.99   ? 407  THR A HG1  1 c 
ATOM   6116  H  HG21 . THR A 1 401 ? 1.978   11.365  -7.094  1   42.19   ? 407  THR A HG21 1 c 
ATOM   6117  H  HG22 . THR A 1 401 ? 3.292   12.242  -7.243  1   42.19   ? 407  THR A HG22 1 c 
ATOM   6118  H  HG23 . THR A 1 401 ? 3.003   11.469  -5.888  1   42.167  ? 407  THR A HG23 1 c 
ATOM   6119  N  N    . ALA A 1 402 ? 5.788   11.356  -5.036  1   35.712  ? 408  ALA A N    1 ? 
ATOM   6120  C  CA   . ALA A 1 402 ? 6.227   11.415  -3.646  1   34.553  ? 408  ALA A CA   1 ? 
ATOM   6121  C  C    . ALA A 1 402 ? 5.049   11.525  -2.66   1   34.288  ? 408  ALA A C    1 ? 
ATOM   6122  O  O    . ALA A 1 402 ? 4.089   12.238  -2.882  1   33.464  ? 408  ALA A O    1 ? 
ATOM   6123  C  CB   . ALA A 1 402 ? 7.211   12.579  -3.496  1   32.134  ? 408  ALA A CB   1 ? 
ATOM   6124  H  H    . ALA A 1 402 ? 5.723   12.14   -5.502  1   35.728  ? 408  ALA A H    1 c 
ATOM   6125  H  HA   . ALA A 1 402 ? 6.709   10.569  -3.445  1   34.244  ? 408  ALA A HA   1 c 
ATOM   6126  H  HB1  . ALA A 1 402 ? 8.023   12.389  -3.996  1   32.806  ? 408  ALA A HB1  1 c 
ATOM   6127  H  HB2  . ALA A 1 402 ? 6.808   13.395  -3.837  1   32.843  ? 408  ALA A HB2  1 c 
ATOM   6128  H  HB3  . ALA A 1 402 ? 7.433   12.7    -2.558  1   32.847  ? 408  ALA A HB3  1 c 
ATOM   6129  N  N    . ALA A 1 403 ? 5.145   10.886  -1.495  1   36.594  ? 409  ALA A N    1 ? 
ATOM   6130  C  CA   . ALA A 1 403 ? 4.164   11.117  -0.435  1   32.914  ? 409  ALA A CA   1 ? 
ATOM   6131  C  C    . ALA A 1 403 ? 4.658   10.44   0.836   1   30.636  ? 409  ALA A C    1 ? 
ATOM   6132  O  O    . ALA A 1 403 ? 5.44    9.48    0.795   1   30.224  ? 409  ALA A O    1 ? 
ATOM   6133  C  CB   . ALA A 1 403 ? 2.8     10.558  -0.837  1   35.105  ? 409  ALA A CB   1 ? 
ATOM   6134  H  H    . ALA A 1 403 ? 5.828   10.296  -1.352  1   35.125  ? 409  ALA A H    1 c 
ATOM   6135  H  HA   . ALA A 1 403 ? 4.092   12.098  -0.27   1   33.531  ? 409  ALA A HA   1 c 
ATOM   6136  H  HB1  . ALA A 1 403 ? 2.487   10.995  -1.645  1   34.507  ? 409  ALA A HB1  1 c 
ATOM   6137  H  HB2  . ALA A 1 403 ? 2.874   9.603   -0.999  1   34.461  ? 409  ALA A HB2  1 c 
ATOM   6138  H  HB3  . ALA A 1 403 ? 2.161   10.712  -0.122  1   34.461  ? 409  ALA A HB3  1 c 
ATOM   6139  N  N    . HIS A 1 404 ? 4.19    10.944  1.976   1   31.243  ? 410  HIS A N    1 ? 
ATOM   6140  C  CA   . HIS A 1 404 ? 4.452   10.277  3.228   1   31.258  ? 410  HIS A CA   1 ? 
ATOM   6141  C  C    . HIS A 1 404 ? 3.163   10.359  4.01    1   34.994  ? 410  HIS A C    1 ? 
ATOM   6142  O  O    . HIS A 1 404 ? 2.956   11.308  4.744   1   43.77   ? 410  HIS A O    1 ? 
ATOM   6143  C  CB   . HIS A 1 404 ? 5.671   10.875  3.941   1   34.301  ? 410  HIS A CB   1 ? 
ATOM   6144  C  CG   . HIS A 1 404 ? 6.086   9.987   5.062   1   34.915  ? 410  HIS A CG   1 ? 
ATOM   6145  N  ND1  . HIS A 1 404 ? 6.415   10.428  6.315   1   33.617  ? 410  HIS A ND1  1 ? 
ATOM   6146  C  CD2  . HIS A 1 404 ? 6.159   8.655   5.113   1   34.557  ? 410  HIS A CD2  1 ? 
ATOM   6147  C  CE1  . HIS A 1 404 ? 6.745   9.4     7.063   1   35.977  ? 410  HIS A CE1  1 ? 
ATOM   6148  N  NE2  . HIS A 1 404 ? 6.579   8.313   6.37    1   32.523  ? 410  HIS A NE2  1 ? 
ATOM   6149  H  H    . HIS A 1 404 ? 3.704   11.719  1.973   1   31.157  ? 410  HIS A H    1 c 
ATOM   6150  H  HA   . HIS A 1 404 ? 4.632   9.324   3.035   1   32.515  ? 410  HIS A HA   1 c 
ATOM   6151  H  HB2  . HIS A 1 404 ? 6.409   10.958  3.301   1   33.806  ? 410  HIS A HB2  1 c 
ATOM   6152  H  HB3  . HIS A 1 404 ? 5.441   11.763  4.293   1   33.795  ? 410  HIS A HB3  1 c 
ATOM   6153  H  HD1  . HIS A 1 404 ? 6.416   11.264  6.566   0   33.69   ? 410  HIS A HD1  1 c 
ATOM   6154  H  HD2  . HIS A 1 404 ? 5.989   8.056   4.413   1   34.16   ? 410  HIS A HD2  1 c 
ATOM   6155  H  HE1  . HIS A 1 404 ? 7.005   9.441   7.961   1   34.633  ? 410  HIS A HE1  1 c 
ATOM   6156  H  HE2  . HIS A 1 404 ? 6.73    7.495   6.66    0   32.29   ? 410  HIS A HE2  1 c 
ATOM   6157  N  N    . THR A 1 405 ? 2.264   9.411   3.772   1   36.309  ? 411  THR A N    1 ? 
ATOM   6158  C  CA   . THR A 1 405 ? 0.979   9.439   4.435   1   38.773  ? 411  THR A CA   1 ? 
ATOM   6159  C  C    . THR A 1 405 ? 1.066   8.531   5.652   1   41.951  ? 411  THR A C    1 ? 
ATOM   6160  O  O    . THR A 1 405 ? 1.087   7.313   5.496   1   44.957  ? 411  THR A O    1 ? 
ATOM   6161  C  CB   . THR A 1 405 ? -0.115  8.952   3.486   1   40.201  ? 411  THR A CB   1 ? 
ATOM   6162  O  OG1  . THR A 1 405 ? 0.105   9.668   2.275   1   33.909  ? 411  THR A OG1  1 ? 
ATOM   6163  C  CG2  . THR A 1 405 ? -1.483  9.131   4.121   1   37.242  ? 411  THR A CG2  1 ? 
ATOM   6164  H  H    . THR A 1 405 ? 2.451   8.736   3.185   1   36.477  ? 411  THR A H    1 c 
ATOM   6165  H  HA   . THR A 1 405 ? 0.776   10.356  4.718   1   39.172  ? 411  THR A HA   1 c 
ATOM   6166  H  HB   . THR A 1 405 ? 0.015   7.989   3.31    1   38.144  ? 411  THR A HB   1 c 
ATOM   6167  H  HG1  . THR A 1 405 ? 0.051   10.526  2.413   0   33.98   ? 411  THR A HG1  1 c 
ATOM   6168  H  HG21 . THR A 1 405 ? -2.172  9.005   3.447   1   38.1    ? 411  THR A HG21 1 c 
ATOM   6169  H  HG22 . THR A 1 405 ? -1.555  10.028  4.491   1   38.104  ? 411  THR A HG22 1 c 
ATOM   6170  H  HG23 . THR A 1 405 ? -1.602  8.478   4.832   1   38.112  ? 411  THR A HG23 1 c 
ATOM   6171  N  N    . ILE A 1 406 ? 1.041   9.143   6.842   1   46.567  ? 412  ILE A N    1 ? 
ATOM   6172  C  CA   . ILE A 1 406 ? 1.268   8.442   8.097   1   48.501  ? 412  ILE A CA   1 ? 
ATOM   6173  C  C    . ILE A 1 406 ? -0.094  8.102   8.722   1   49.866  ? 412  ILE A C    1 ? 
ATOM   6174  O  O    . ILE A 1 406 ? -0.863  8.989   9.145   1   44.371  ? 412  ILE A O    1 ? 
ATOM   6175  C  CB   . ILE A 1 406 ? 2.153   9.313   9.025   1   51.145  ? 412  ILE A CB   1 ? 
ATOM   6176  C  CG1  . ILE A 1 406 ? 3.355   9.932   8.264   1   49.522  ? 412  ILE A CG1  1 ? 
ATOM   6177  C  CG2  . ILE A 1 406 ? 2.585   8.547   10.281  1   50.178  ? 412  ILE A CG2  1 ? 
ATOM   6178  C  CD1  . ILE A 1 406 ? 4.112   10.993  9.038   1   44.697  ? 412  ILE A CD1  1 ? 
ATOM   6179  H  H    . ILE A 1 406 ? 0.861   10.038  6.873   1   45.768  ? 412  ILE A H    1 c 
ATOM   6180  H  HA   . ILE A 1 406 ? 1.748   7.617   7.906   1   48.77   ? 412  ILE A HA   1 c 
ATOM   6181  H  HB   . ILE A 1 406 ? 1.596   10.059  9.325   1   50.131  ? 412  ILE A HB   1 c 
ATOM   6182  H  HG12 . ILE A 1 406 ? 3.977   9.214   8.029   1   48.707  ? 412  ILE A HG12 1 c 
ATOM   6183  H  HG13 . ILE A 1 406 ? 3.031   10.329  7.431   1   48.675  ? 412  ILE A HG13 1 c 
ATOM   6184  H  HG21 . ILE A 1 406 ? 3.099   9.132   10.861  1   50.226  ? 412  ILE A HG21 1 c 
ATOM   6185  H  HG22 . ILE A 1 406 ? 3.132   7.785   10.026  1   50.403  ? 412  ILE A HG22 1 c 
ATOM   6186  H  HG23 . ILE A 1 406 ? 1.799   8.232   10.759  1   50.4    ? 412  ILE A HG23 1 c 
ATOM   6187  H  HD11 . ILE A 1 406 ? 3.494   11.693  9.324   1   46.082  ? 412  ILE A HD11 1 c 
ATOM   6188  H  HD12 . ILE A 1 406 ? 4.8     11.384  8.466   1   46.083  ? 412  ILE A HD12 1 c 
ATOM   6189  H  HD13 . ILE A 1 406 ? 4.534   10.594  9.823   1   46.117  ? 412  ILE A HD13 1 c 
ATOM   6190  N  N    . PRO A 1 407 ? -0.414  6.8     8.863   1   45.738  ? 413  PRO A N    1 ? 
ATOM   6191  C  CA   . PRO A 1 407 ? -1.663  6.373   9.503   1   50.163  ? 413  PRO A CA   1 ? 
ATOM   6192  C  C    . PRO A 1 407 ? -1.866  6.822   10.956  1   57.684  ? 413  PRO A C    1 ? 
ATOM   6193  O  O    . PRO A 1 407 ? -0.926  7.252   11.636  1   53.026  ? 413  PRO A O    1 ? 
ATOM   6194  C  CB   . PRO A 1 407 ? -1.641  4.844   9.409   1   46.544  ? 413  PRO A CB   1 ? 
ATOM   6195  C  CG   . PRO A 1 407 ? -0.193  4.512   9.218   1   47.839  ? 413  PRO A CG   1 ? 
ATOM   6196  C  CD   . PRO A 1 407 ? 0.474   5.687   8.527   1   51.547  ? 413  PRO A CD   1 ? 
ATOM   6197  H  HA   . PRO A 1 407 ? -2.413  6.714   8.954   1   49.877  ? 413  PRO A HA   1 c 
ATOM   6198  H  HB2  . PRO A 1 407 ? -1.992  4.433   10.234  1   47.676  ? 413  PRO A HB2  1 c 
ATOM   6199  H  HB3  . PRO A 1 407 ? -2.178  4.531   8.643   1   47.633  ? 413  PRO A HB3  1 c 
ATOM   6200  H  HG2  . PRO A 1 407 ? 0.233   4.344   10.085  1   48.346  ? 413  PRO A HG2  1 c 
ATOM   6201  H  HG3  . PRO A 1 407 ? -0.101  3.704   8.672   1   48.346  ? 413  PRO A HG3  1 c 
ATOM   6202  H  HD2  . PRO A 1 407 ? 1.38    5.831   8.881   1   49.294  ? 413  PRO A HD2  1 c 
ATOM   6203  H  HD3  . PRO A 1 407 ? 0.521   5.548   7.555   1   49.302  ? 413  PRO A HD3  1 c 
ATOM   6204  N  N    . ALA A 1 408 ? -3.128  6.7     11.407  1   57.826  ? 414  ALA A N    1 ? 
ATOM   6205  C  CA   . ALA A 1 408 ? -3.58   7.096   12.737  1   44.652  ? 414  ALA A CA   1 ? 
ATOM   6206  C  C    . ALA A 1 408 ? -2.813  6.364   13.842  1   39.897  ? 414  ALA A C    1 ? 
ATOM   6207  O  O    . ALA A 1 408 ? -2.511  6.969   14.862  1   39.34   ? 414  ALA A O    1 ? 
ATOM   6208  C  CB   . ALA A 1 408 ? -5.077  6.862   12.851  1   41.955  ? 414  ALA A CB   1 ? 
ATOM   6209  H  H    . ALA A 1 408 ? -3.747  6.339   10.84   1   54.32   ? 414  ALA A H    1 c 
ATOM   6210  H  HA   . ALA A 1 408 ? -3.403  8.072   12.839  1   45.497  ? 414  ALA A HA   1 c 
ATOM   6211  H  HB1  . ALA A 1 408 ? -5.542  7.38    12.173  1   42.734  ? 414  ALA A HB1  1 c 
ATOM   6212  H  HB2  . ALA A 1 408 ? -5.271  5.918   12.723  1   42.734  ? 414  ALA A HB2  1 c 
ATOM   6213  H  HB3  . ALA A 1 408 ? -5.385  7.136   13.731  1   42.734  ? 414  ALA A HB3  1 c 
ATOM   6214  N  N    . CYS A 1 409 ? -2.475  5.084   13.625  1   37.247  ? 415  CYS A N    1 ? 
ATOM   6215  C  CA   . CYS A 1 409 ? -1.785  4.25    14.604  1   36.313  ? 415  CYS A CA   1 ? 
ATOM   6216  C  C    . CYS A 1 409 ? -0.886  3.218   13.911  1   39.049  ? 415  CYS A C    1 ? 
ATOM   6217  O  O    . CYS A 1 409 ? -1.325  2.559   12.987  1   36.311  ? 415  CYS A O    1 ? 
ATOM   6218  C  CB   . CYS A 1 409 ? -2.791  3.457   15.431  1   37.828  ? 415  CYS A CB   1 ? 
ATOM   6219  S  SG   . CYS A 1 409 ? -2.069  2.326   16.65   1   43.904  ? 415  CYS A SG   1 ? 
ATOM   6220  H  H    . CYS A 1 409 ? -2.695  4.709   12.821  1   37.895  ? 415  CYS A H    1 c 
ATOM   6221  H  HA   . CYS A 1 409 ? -1.231  4.828   15.183  1   37.335  ? 415  CYS A HA   1 c 
ATOM   6222  H  HB2  . CYS A 1 409 ? -3.375  4.088   15.908  1   38.536  ? 415  CYS A HB2  1 c 
ATOM   6223  H  HB3  . CYS A 1 409 ? -3.356  2.931   14.822  1   38.536  ? 415  CYS A HB3  1 c 
ATOM   6224  H  HG   . CYS A 1 409 ? -3.121  1.87    17.084  0   44.34   ? 415  CYS A HG   1 c 
ATOM   6225  N  N    . THR A 1 410 ? 0.362   3.054   14.376  1   37.657  ? 416  THR A N    1 ? 
ATOM   6226  C  CA   . THR A 1 410 ? 1.181   1.905   14.012  1   39.713  ? 416  THR A CA   1 ? 
ATOM   6227  C  C    . THR A 1 410 ? 1.578   1.176   15.292  1   39.165  ? 416  THR A C    1 ? 
ATOM   6228  O  O    . THR A 1 410 ? 2.179   1.785   16.17   1   40.868  ? 416  THR A O    1 ? 
ATOM   6229  C  CB   . THR A 1 410 ? 2.443   2.321   13.227  1   36.38   ? 416  THR A CB   1 ? 
ATOM   6230  O  OG1  . THR A 1 410 ? 2.101   2.96    11.992  1   31.671  ? 416  THR A OG1  1 ? 
ATOM   6231  C  CG2  . THR A 1 410 ? 3.25    1.086   12.88   1   34.877  ? 416  THR A CG2  1 ? 
ATOM   6232  H  H    . THR A 1 410 ? 0.714   3.681   14.939  1   38.384  ? 416  THR A H    1 c 
ATOM   6233  H  HA   . THR A 1 410 ? 0.65    1.303   13.453  1   38.58   ? 416  THR A HA   1 c 
ATOM   6234  H  HB   . THR A 1 410 ? 2.993   2.932   13.773  1   35.685  ? 416  THR A HB   1 c 
ATOM   6235  H  HG1  . THR A 1 410 ? 1.615   2.424   11.511  0   32.01   ? 416  THR A HG1  1 c 
ATOM   6236  H  HG21 . THR A 1 410 ? 3.969   1.329   12.272  1   35.318  ? 416  THR A HG21 1 c 
ATOM   6237  H  HG22 . THR A 1 410 ? 2.673   0.43    12.452  1   35.318  ? 416  THR A HG22 1 c 
ATOM   6238  H  HG23 . THR A 1 410 ? 3.629   0.704   13.69   1   35.327  ? 416  THR A HG23 1 c 
ATOM   6239  N  N    . TRP A 1 411 ? 1.337   -0.141  15.368  1   39.338  ? 417  TRP A N    1 ? 
ATOM   6240  C  CA   . TRP A 1 411 ? 1.531   -0.87   16.617  1   42.159  ? 417  TRP A CA   1 ? 
ATOM   6241  C  C    . TRP A 1 411 ? 2.421   -2.077  16.349  1   34.623  ? 417  TRP A C    1 ? 
ATOM   6242  O  O    . TRP A 1 411 ? 2.047   -2.953  15.581  1   40.381  ? 417  TRP A O    1 ? 
ATOM   6243  C  CB   . TRP A 1 411 ? 0.172   -1.25   17.248  1   46.187  ? 417  TRP A CB   1 ? 
ATOM   6244  C  CG   . TRP A 1 411 ? 0.182   -2.167  18.455  1   44.348  ? 417  TRP A CG   1 ? 
ATOM   6245  C  CD1  . TRP A 1 411 ? -0.684  -3.217  18.659  1   41.225  ? 417  TRP A CD1  1 ? 
ATOM   6246  C  CD2  . TRP A 1 411 ? 1.057   -2.135  19.615  1   33.154  ? 417  TRP A CD2  1 ? 
ATOM   6247  N  NE1  . TRP A 1 411 ? -0.405  -3.83   19.853  1   37.463  ? 417  TRP A NE1  1 ? 
ATOM   6248  C  CE2  . TRP A 1 411 ? 0.653   -3.188  20.461  1   36.947  ? 417  TRP A CE2  1 ? 
ATOM   6249  C  CE3  . TRP A 1 411 ? 2.111   -1.319  20.025  1   41.915  ? 417  TRP A CE3  1 ? 
ATOM   6250  C  CZ2  . TRP A 1 411 ? 1.268   -3.431  21.685  1   38.19   ? 417  TRP A CZ2  1 ? 
ATOM   6251  C  CZ3  . TRP A 1 411 ? 2.719   -1.557  21.239  1   45.988  ? 417  TRP A CZ3  1 ? 
ATOM   6252  C  CH2  . TRP A 1 411 ? 2.313   -2.612  22.052  1   42.312  ? 417  TRP A CH2  1 ? 
ATOM   6253  H  H    . TRP A 1 411 ? 1.049   -0.595  14.629  1   39.899  ? 417  TRP A H    1 c 
ATOM   6254  H  HA   . TRP A 1 411 ? 2.003   -0.272  17.254  1   40.663  ? 417  TRP A HA   1 c 
ATOM   6255  H  HB2  . TRP A 1 411 ? -0.288  -0.42   17.495  1   44.826  ? 417  TRP A HB2  1 c 
ATOM   6256  H  HB3  . TRP A 1 411 ? -0.379  -1.666  16.551  1   44.824  ? 417  TRP A HB3  1 c 
ATOM   6257  H  HD1  . TRP A 1 411 ? -1.365  -3.489  18.065  1   40.946  ? 417  TRP A HD1  1 c 
ATOM   6258  H  HE1  . TRP A 1 411 ? -0.833  -4.519  20.178  1   38.237  ? 417  TRP A HE1  1 c 
ATOM   6259  H  HE3  . TRP A 1 411 ? 2.394   -0.606  19.483  1   40.578  ? 417  TRP A HE3  1 c 
ATOM   6260  H  HZ2  . TRP A 1 411 ? 0.988   -4.142  22.236  1   38.869  ? 417  TRP A HZ2  1 c 
ATOM   6261  H  HZ3  . TRP A 1 411 ? 3.441   -1.014  21.511  1   43.97   ? 417  TRP A HZ3  1 c 
ATOM   6262  H  HH2  . TRP A 1 411 ? 2.748   -2.758  22.874  1   42.033  ? 417  TRP A HH2  1 c 
ATOM   6263  N  N    . TYR A 1 412 ? 3.591   -2.091  16.988  1   32.554  ? 418  TYR A N    1 ? 
ATOM   6264  C  CA   . TYR A 1 412 ? 4.541   -3.187  16.891  1   37.086  ? 418  TYR A CA   1 ? 
ATOM   6265  C  C    . TYR A 1 412 ? 4.495   -3.958  18.204  1   37.211  ? 418  TYR A C    1 ? 
ATOM   6266  O  O    . TYR A 1 412 ? 5.105   -3.545  19.191  1   37.923  ? 418  TYR A O    1 ? 
ATOM   6267  C  CB   . TYR A 1 412 ? 5.987   -2.728  16.631  1   39.185  ? 418  TYR A CB   1 ? 
ATOM   6268  C  CG   . TYR A 1 412 ? 6.196   -2.038  15.284  1   40.583  ? 418  TYR A CG   1 ? 
ATOM   6269  C  CD1  . TYR A 1 412 ? 6.471   -2.765  14.134  1   32.974  ? 418  TYR A CD1  1 ? 
ATOM   6270  C  CD2  . TYR A 1 412 ? 6.177   -0.647  15.194  1   37.676  ? 418  TYR A CD2  1 ? 
ATOM   6271  C  CE1  . TYR A 1 412 ? 6.641   -2.131  12.912  1   37.555  ? 418  TYR A CE1  1 ? 
ATOM   6272  C  CE2  . TYR A 1 412 ? 6.367   -0.001  13.989  1   33.658  ? 418  TYR A CE2  1 ? 
ATOM   6273  C  CZ   . TYR A 1 412 ? 6.597   -0.743  12.847  1   35.441  ? 418  TYR A CZ   1 ? 
ATOM   6274  O  OH   . TYR A 1 412 ? 6.784   -0.053  11.691  1   34.769  ? 418  TYR A OH   1 ? 
ATOM   6275  H  H    . TYR A 1 412 ? 3.811   -1.377  17.514  1   34.134  ? 418  TYR A H    1 c 
ATOM   6276  H  HA   . TYR A 1 412 ? 4.264   -3.788  16.152  1   36.734  ? 418  TYR A HA   1 c 
ATOM   6277  H  HB2  . TYR A 1 412 ? 6.25    -2.108  17.347  1   39.037  ? 418  TYR A HB2  1 c 
ATOM   6278  H  HB3  . TYR A 1 412 ? 6.578   -3.51   16.681  1   39.055  ? 418  TYR A HB3  1 c 
ATOM   6279  H  HD1  . TYR A 1 412 ? 6.484   -3.708  14.173  1   35.724  ? 418  TYR A HD1  1 c 
ATOM   6280  H  HD2  . TYR A 1 412 ? 6.004   -0.136  15.969  1   37.283  ? 418  TYR A HD2  1 c 
ATOM   6281  H  HE1  . TYR A 1 412 ? 6.813   -2.635  12.135  1   35.966  ? 418  TYR A HE1  1 c 
ATOM   6282  H  HE2  . TYR A 1 412 ? 6.328   0.937   13.942  1   35.109  ? 418  TYR A HE2  1 c 
ATOM   6283  H  HH   . TYR A 1 412 ? 6.042   0.045   11.277  0   35.11   ? 418  TYR A HH   1 c 
ATOM   6284  N  N    . PRO A 1 413 ? 3.708   -5.053  18.29   1   43.928  ? 419  PRO A N    1 ? 
ATOM   6285  C  CA   . PRO A 1 413 ? 3.396   -5.638  19.599  1   47.428  ? 419  PRO A CA   1 ? 
ATOM   6286  C  C    . PRO A 1 413 ? 4.484   -6.44   20.307  1   42.32   ? 419  PRO A C    1 ? 
ATOM   6287  O  O    . PRO A 1 413 ? 4.435   -6.597  21.515  1   46.358  ? 419  PRO A O    1 ? 
ATOM   6288  C  CB   . PRO A 1 413 ? 2.101   -6.448  19.338  1   47.416  ? 419  PRO A CB   1 ? 
ATOM   6289  C  CG   . PRO A 1 413 ? 2.076   -6.712  17.848  1   46.327  ? 419  PRO A CG   1 ? 
ATOM   6290  C  CD   . PRO A 1 413 ? 2.905   -5.614  17.194  1   45.72   ? 419  PRO A CD   1 ? 
ATOM   6291  H  HA   . PRO A 1 413 ? 3.158   -4.879  20.186  1   45.612  ? 419  PRO A HA   1 c 
ATOM   6292  H  HB2  . PRO A 1 413 ? 2.111   -7.295  19.842  1   47.129  ? 419  PRO A HB2  1 c 
ATOM   6293  H  HB3  . PRO A 1 413 ? 1.307   -5.932  19.614  1   47.107  ? 419  PRO A HB3  1 c 
ATOM   6294  H  HG2  . PRO A 1 413 ? 2.458   -7.592  17.65   1   46.434  ? 419  PRO A HG2  1 c 
ATOM   6295  H  HG3  . PRO A 1 413 ? 1.156   -6.691  17.512  1   46.434  ? 419  PRO A HG3  1 c 
ATOM   6296  H  HD2  . PRO A 1 413 ? 3.481   -5.984  16.49   1   45.239  ? 419  PRO A HD2  1 c 
ATOM   6297  H  HD3  . PRO A 1 413 ? 2.322   -4.932  16.801  1   45.206  ? 419  PRO A HD3  1 c 
ATOM   6298  N  N    . GLU A 1 414 ? 5.476   -6.938  19.585  1   38.278  ? 420  GLU A N    1 ? 
ATOM   6299  C  CA   . GLU A 1 414 ? 6.532   -7.703  20.236  1   46.011  ? 420  GLU A CA   1 ? 
ATOM   6300  C  C    . GLU A 1 414 ? 7.641   -6.753  20.699  1   46.978  ? 420  GLU A C    1 ? 
ATOM   6301  O  O    . GLU A 1 414 ? 8.103   -6.828  21.839  1   44.599  ? 420  GLU A O    1 ? 
ATOM   6302  C  CB   . GLU A 1 414 ? 7.014   -8.775  19.258  1   52.491  ? 420  GLU A CB   1 ? 
ATOM   6303  C  CG   . GLU A 1 414 ? 5.945   -9.821  18.955  1   63.343  ? 420  GLU A CG   1 ? 
ATOM   6304  C  CD   . GLU A 1 414 ? 5.738   -10.044 17.471  1   74.115  ? 420  GLU A CD   1 ? 
ATOM   6305  O  OE1  . GLU A 1 414 ? 4.568   -9.972  17.02   1   81.336  ? 420  GLU A OE1  1 ? 
ATOM   6306  O  OE2  . GLU A 1 414 ? 6.753   -10.248 16.77   1   82.444  ? 420  GLU A OE2  1 ? 
ATOM   6307  H  H    . GLU A 1 414 ? 5.504   -6.81   18.681  1   41.067  ? 420  GLU A H    1 c 
ATOM   6308  H  HA   . GLU A 1 414 ? 6.151   -8.156  21.031  1   45.634  ? 420  GLU A HA   1 c 
ATOM   6309  H  HB2  . GLU A 1 414 ? 7.296   -8.339  18.427  1   53.302  ? 420  GLU A HB2  1 c 
ATOM   6310  H  HB3  . GLU A 1 414 ? 7.797   -9.223  19.641  1   53.198  ? 420  GLU A HB3  1 c 
ATOM   6311  H  HG2  . GLU A 1 414 ? 6.203   -10.673 19.367  1   62.895  ? 420  GLU A HG2  1 c 
ATOM   6312  H  HG3  . GLU A 1 414 ? 5.094   -9.54   19.353  1   62.748  ? 420  GLU A HG3  1 c 
ATOM   6313  N  N    . THR A 1 415 ? 8.089   -5.885  19.774  1   41.821  ? 421  THR A N    1 ? 
ATOM   6314  C  CA   . THR A 1 415 ? 9.057   -4.849  20.074  1   40.798  ? 421  THR A CA   1 ? 
ATOM   6315  C  C    . THR A 1 415 ? 8.445   -3.859  21.074  1   37.8    ? 421  THR A C    1 ? 
ATOM   6316  O  O    . THR A 1 415 ? 9.192   -3.211  21.798  1   41.45   ? 421  THR A O    1 ? 
ATOM   6317  C  CB   . THR A 1 415 ? 9.45    -4.164  18.76   1   38.203  ? 421  THR A CB   1 ? 
ATOM   6318  O  OG1  . THR A 1 415 ? 9.782   -5.18   17.82   1   37.514  ? 421  THR A OG1  1 ? 
ATOM   6319  C  CG2  . THR A 1 415 ? 10.63   -3.228  18.928  1   42.619  ? 421  THR A CG2  1 ? 
ATOM   6320  H  H    . THR A 1 415 ? 7.775   -5.951  18.918  1   42.711  ? 421  THR A H    1 c 
ATOM   6321  H  HA   . THR A 1 415 ? 9.854   -5.263  20.472  1   39.973  ? 421  THR A HA   1 c 
ATOM   6322  H  HB   . THR A 1 415 ? 8.681   -3.648  18.42   1   39.308  ? 421  THR A HB   1 c 
ATOM   6323  H  HG1  . THR A 1 415 ? 10.46   -5.643  18.14   0   37.68   ? 421  THR A HG1  1 c 
ATOM   6324  H  HG21 . THR A 1 415 ? 10.899  -2.886  18.06   1   41.245  ? 421  THR A HG21 1 c 
ATOM   6325  H  HG22 . THR A 1 415 ? 11.372  -3.711  19.329  1   41.254  ? 421  THR A HG22 1 c 
ATOM   6326  H  HG23 . THR A 1 415 ? 10.378  -2.486  19.504  1   41.242  ? 421  THR A HG23 1 c 
ATOM   6327  N  N    . GLU A 1 416 ? 7.109   -3.668  21.02   1   38.659  ? 422  GLU A N    1 ? 
ATOM   6328  C  CA   . GLU A 1 416 ? 6.362   -2.736  21.884  1   41.434  ? 422  GLU A CA   1 ? 
ATOM   6329  C  C    . GLU A 1 416 ? 6.662   -1.272  21.559  1   40.079  ? 422  GLU A C    1 ? 
ATOM   6330  O  O    . GLU A 1 416 ? 6.879   -0.463  22.44   1   40.455  ? 422  GLU A O    1 ? 
ATOM   6331  C  CB   . GLU A 1 416 ? 6.566   -3.003  23.382  1   43.595  ? 422  GLU A CB   1 ? 
ATOM   6332  C  CG   . GLU A 1 416 ? 6.071   -4.394  23.751  1   41.035  ? 422  GLU A CG   1 ? 
ATOM   6333  C  CD   . GLU A 1 416 ? 5.992   -4.722  25.222  1   47.461  ? 422  GLU A CD   1 ? 
ATOM   6334  O  OE1  . GLU A 1 416 ? 5.22    -5.679  25.477  1   45.853  ? 422  GLU A OE1  1 ? 
ATOM   6335  O  OE2  . GLU A 1 416 ? 6.692   -4.09   26.056  1   41.831  ? 422  GLU A OE2  1 ? 
ATOM   6336  H  H    . GLU A 1 416 ? 6.634   -4.137  20.396  1   39.127  ? 422  GLU A H    1 c 
ATOM   6337  H  HA   . GLU A 1 416 ? 5.398   -2.882  21.706  1   41.014  ? 422  GLU A HA   1 c 
ATOM   6338  H  HB2  . GLU A 1 416 ? 7.515   -2.909  23.604  1   42.472  ? 422  GLU A HB2  1 c 
ATOM   6339  H  HB3  . GLU A 1 416 ? 6.068   -2.336  23.898  1   42.45   ? 422  GLU A HB3  1 c 
ATOM   6340  H  HG2  . GLU A 1 416 ? 5.178   -4.518  23.365  1   43.05   ? 422  GLU A HG2  1 c 
ATOM   6341  H  HG3  . GLU A 1 416 ? 6.657   -5.055  23.325  1   43.013  ? 422  GLU A HG3  1 c 
ATOM   6342  N  N    . PHE A 1 417 ? 6.675   -0.936  20.272  1   44.73   ? 423  PHE A N    1 ? 
ATOM   6343  C  CA   . PHE A 1 417 ? 6.693   0.443   19.842  1   42.39   ? 423  PHE A CA   1 ? 
ATOM   6344  C  C    . PHE A 1 417 ? 5.29    0.752   19.32   1   41.469  ? 423  PHE A C    1 ? 
ATOM   6345  O  O    . PHE A 1 417 ? 4.685   -0.079  18.637  1   37.577  ? 423  PHE A O    1 ? 
ATOM   6346  C  CB   . PHE A 1 417 ? 7.722   0.655   18.719  1   45.093  ? 423  PHE A CB   1 ? 
ATOM   6347  C  CG   . PHE A 1 417 ? 9.188   0.427   19.068  1   45.968  ? 423  PHE A CG   1 ? 
ATOM   6348  C  CD1  . PHE A 1 417 ? 9.639   0.518   20.38   1   45.163  ? 423  PHE A CD1  1 ? 
ATOM   6349  C  CD2  . PHE A 1 417 ? 10.136  0.233   18.056  1   45.683  ? 423  PHE A CD2  1 ? 
ATOM   6350  C  CE1  . PHE A 1 417 ? 10.995  0.37    20.691  1   46.047  ? 423  PHE A CE1  1 ? 
ATOM   6351  C  CE2  . PHE A 1 417 ? 11.48   0.091   18.365  1   42.246  ? 423  PHE A CE2  1 ? 
ATOM   6352  C  CZ   . PHE A 1 417 ? 11.91   0.168   19.688  1   40.443  ? 423  PHE A CZ   1 ? 
ATOM   6353  H  H    . PHE A 1 417 ? 6.67    -1.594  19.636  1   42.975  ? 423  PHE A H    1 c 
ATOM   6354  H  HA   . PHE A 1 417 ? 6.904   1.036   20.609  1   43.023  ? 423  PHE A HA   1 c 
ATOM   6355  H  HB2  . PHE A 1 417 ? 7.485   0.058   17.975  1   44.657  ? 423  PHE A HB2  1 c 
ATOM   6356  H  HB3  . PHE A 1 417 ? 7.623   1.575   18.387  1   44.643  ? 423  PHE A HB3  1 c 
ATOM   6357  H  HD1  . PHE A 1 417 ? 9.019   0.672   21.075  1   45.45   ? 423  PHE A HD1  1 c 
ATOM   6358  H  HD2  . PHE A 1 417 ? 9.856   0.194   17.156  1   44.885  ? 423  PHE A HD2  1 c 
ATOM   6359  H  HE1  . PHE A 1 417 ? 11.281  0.413   21.588  1   44.409  ? 423  PHE A HE1  1 c 
ATOM   6360  H  HE2  . PHE A 1 417 ? 12.107  -0.061  17.675  1   42.654  ? 423  PHE A HE2  1 c 
ATOM   6361  H  HZ   . PHE A 1 417 ? 12.823  0.049   19.897  1   42.19   ? 423  PHE A HZ   1 c 
ATOM   6362  N  N    . CYS A 1 418 ? 4.814   1.962   19.617  1   34.042  ? 424  CYS A N    1 ? 
ATOM   6363  C  CA   . CYS A 1 418 ? 3.512   2.398   19.173  1   36.691  ? 424  CYS A CA   1 ? 
ATOM   6364  C  C    . CYS A 1 418 ? 3.628   3.824   18.665  1   34.216  ? 424  CYS A C    1 ? 
ATOM   6365  O  O    . CYS A 1 418 ? 4.123   4.665   19.397  1   34.82   ? 424  CYS A O    1 ? 
ATOM   6366  C  CB   . CYS A 1 418 ? 2.528   2.405   20.342  1   43.113  ? 424  CYS A CB   1 ? 
ATOM   6367  S  SG   . CYS A 1 418 ? 0.912   3.103   19.91   1   43.237  ? 424  CYS A SG   1 ? 
ATOM   6368  H  H    . CYS A 1 418 ? 5.322   2.535   20.117  1   36.37   ? 424  CYS A H    1 c 
ATOM   6369  H  HA   . CYS A 1 418 ? 3.202   1.809   18.441  1   36.763  ? 424  CYS A HA   1 c 
ATOM   6370  H  HB2  . CYS A 1 418 ? 2.396   1.484   20.659  1   41.505  ? 424  CYS A HB2  1 c 
ATOM   6371  H  HB3  . CYS A 1 418 ? 2.908   2.929   21.081  1   41.498  ? 424  CYS A HB3  1 c 
ATOM   6372  H  HG   . CYS A 1 418 ? 0.38    2.981   20.983  0   42.67   ? 424  CYS A HG   1 c 
ATOM   6373  N  N    . TYR A 1 419 ? 3.146   4.096   17.453  1   34.178  ? 425  TYR A N    1 ? 
ATOM   6374  C  CA   . TYR A 1 419 ? 3.233   5.437   16.875  1   38.516  ? 425  TYR A CA   1 ? 
ATOM   6375  C  C    . TYR A 1 419 ? 1.806   5.853   16.594  1   32.049  ? 425  TYR A C    1 ? 
ATOM   6376  O  O    . TYR A 1 419 ? 1.071   5.107   15.989  1   39.591  ? 425  TYR A O    1 ? 
ATOM   6377  C  CB   . TYR A 1 419 ? 4.071   5.579   15.577  1   37.25   ? 425  TYR A CB   1 ? 
ATOM   6378  C  CG   . TYR A 1 419 ? 5.438   4.926   15.737  1   35.942  ? 425  TYR A CG   1 ? 
ATOM   6379  C  CD1  . TYR A 1 419 ? 6.243   5.198   16.84   1   31.023  ? 425  TYR A CD1  1 ? 
ATOM   6380  C  CD2  . TYR A 1 419 ? 5.904   3.991   14.827  1   41.399  ? 425  TYR A CD2  1 ? 
ATOM   6381  C  CE1  . TYR A 1 419 ? 7.453   4.545   17.045  1   38.944  ? 425  TYR A CE1  1 ? 
ATOM   6382  C  CE2  . TYR A 1 419 ? 7.127   3.348   15.009  1   42.099  ? 425  TYR A CE2  1 ? 
ATOM   6383  C  CZ   . TYR A 1 419 ? 7.911   3.623   16.115  1   39.639  ? 425  TYR A CZ   1 ? 
ATOM   6384  O  OH   . TYR A 1 419 ? 9.089   2.938   16.296  1   44.161  ? 425  TYR A OH   1 ? 
ATOM   6385  H  H    . TYR A 1 419 ? 2.751   3.431   16.965  1   35.119  ? 425  TYR A H    1 c 
ATOM   6386  H  HA   . TYR A 1 419 ? 3.611   6.05    17.557  1   36.082  ? 425  TYR A HA   1 c 
ATOM   6387  H  HB2  . TYR A 1 419 ? 3.59    5.15    14.835  1   37.234  ? 425  TYR A HB2  1 c 
ATOM   6388  H  HB3  . TYR A 1 419 ? 4.188   6.533   15.373  1   37.227  ? 425  TYR A HB3  1 c 
ATOM   6389  H  HD1  . TYR A 1 419 ? 5.938   5.808   17.493  1   34.048  ? 425  TYR A HD1  1 c 
ATOM   6390  H  HD2  . TYR A 1 419 ? 5.378   3.777   14.073  1   40.116  ? 425  TYR A HD2  1 c 
ATOM   6391  H  HE1  . TYR A 1 419 ? 7.974   4.745   17.804  1   37.147  ? 425  TYR A HE1  1 c 
ATOM   6392  H  HE2  . TYR A 1 419 ? 7.419   2.711   14.38   1   41.191  ? 425  TYR A HE2  1 c 
ATOM   6393  H  HH   . TYR A 1 419 ? 9.076   2.237   16.744  0   42.97   ? 425  TYR A HH   1 c 
ATOM   6394  N  N    . LEU A 1 420 ? 1.426   7.04    17.043  1   36.604  ? 426  LEU A N    1 ? 
ATOM   6395  C  CA   . LEU A 1 420 ? 0.063   7.512   16.903  1   38.689  ? 426  LEU A CA   1 ? 
ATOM   6396  C  C    . LEU A 1 420 ? 0.067   8.902   16.275  1   38.478  ? 426  LEU A C    1 ? 
ATOM   6397  O  O    . LEU A 1 420 ? 0.906   9.718   16.638  1   33.975  ? 426  LEU A O    1 ? 
ATOM   6398  C  CB   . LEU A 1 420 ? -0.524  7.536   18.323  1   40.175  ? 426  LEU A CB   1 ? 
ATOM   6399  C  CG   . LEU A 1 420 ? -0.899  6.186   18.947  1   40.388  ? 426  LEU A CG   1 ? 
ATOM   6400  C  CD1  . LEU A 1 420 ? -1.336  6.333   20.38   1   45.544  ? 426  LEU A CD1  1 ? 
ATOM   6401  C  CD2  . LEU A 1 420 ? -2.011  5.572   18.184  1   44.085  ? 426  LEU A CD2  1 ? 
ATOM   6402  H  H    . LEU A 1 420 ? 2.037   7.582   17.452  1   35.944  ? 426  LEU A H    1 c 
ATOM   6403  H  HA   . LEU A 1 420 ? -0.447  6.887   16.332  1   38.522  ? 426  LEU A HA   1 c 
ATOM   6404  H  HB2  . LEU A 1 420 ? 0.128   7.978   18.915  1   39.862  ? 426  LEU A HB2  1 c 
ATOM   6405  H  HB3  . LEU A 1 420 ? -1.329  8.102   18.31   1   39.888  ? 426  LEU A HB3  1 c 
ATOM   6406  H  HG   . LEU A 1 420 ? -0.111  5.587   18.908  1   41.959  ? 426  LEU A HG   1 c 
ATOM   6407  H  HD11 . LEU A 1 420 ? -0.596  6.671   20.912  1   43.964  ? 426  LEU A HD11 1 c 
ATOM   6408  H  HD12 . LEU A 1 420 ? -1.613  5.468   20.727  1   43.942  ? 426  LEU A HD12 1 c 
ATOM   6409  H  HD13 . LEU A 1 420 ? -2.081  6.955   20.431  1   43.946  ? 426  LEU A HD13 1 c 
ATOM   6410  H  HD21 . LEU A 1 420 ? -1.71   5.351   17.289  1   42.817  ? 426  LEU A HD21 1 c 
ATOM   6411  H  HD22 . LEU A 1 420 ? -2.752  6.199   18.13   1   42.917  ? 426  LEU A HD22 1 c 
ATOM   6412  H  HD23 . LEU A 1 420 ? -2.306  4.762   18.633  1   42.932  ? 426  LEU A HD23 1 c 
ATOM   6413  N  N    . THR A 1 421 ? -0.985  9.214   15.515  1   37.196  ? 427  THR A N    1 ? 
ATOM   6414  C  CA   . THR A 1 421 ? -1.048  10.426  14.719  1   43.118  ? 427  THR A CA   1 ? 
ATOM   6415  C  C    . THR A 1 421 ? -2.477  10.993  14.701  1   42.664  ? 427  THR A C    1 ? 
ATOM   6416  O  O    . THR A 1 421 ? -3.457  10.248  14.752  1   42.685  ? 427  THR A O    1 ? 
ATOM   6417  C  CB   . THR A 1 421 ? -0.518  9.969   13.351  1   53.172  ? 427  THR A CB   1 ? 
ATOM   6418  O  OG1  . THR A 1 421 ? 0.889   10.275  13.305  1   51.595  ? 427  THR A OG1  1 ? 
ATOM   6419  C  CG2  . THR A 1 421 ? -1.382  10.486  12.218  1   44.221  ? 427  THR A CG2  1 ? 
ATOM   6420  H  H    . THR A 1 421 ? -1.697  8.642   15.493  1   38.796  ? 427  THR A H    1 c 
ATOM   6421  H  HA   . THR A 1 421 ? -0.437  11.091  15.098  1   43.373  ? 427  THR A HA   1 c 
ATOM   6422  H  HB   . THR A 1 421 ? -0.608  8.987   13.321  1   49.051  ? 427  THR A HB   1 c 
ATOM   6423  H  HG1  . THR A 1 421 ? 0.919   11.416  13.495  0   50.13   ? 427  THR A HG1  1 c 
ATOM   6424  H  HG21 . THR A 1 421 ? -0.955  10.283  11.369  1   46.676  ? 427  THR A HG21 1 c 
ATOM   6425  H  HG22 . THR A 1 421 ? -1.486  11.45   12.301  1   46.646  ? 427  THR A HG22 1 c 
ATOM   6426  H  HG23 . THR A 1 421 ? -2.255  10.06   12.249  1   46.664  ? 427  THR A HG23 1 c 
ATOM   6427  N  N    . ASN A 1 422 ? -2.591  12.325  14.657  1   41.866  ? 428  ASN A N    1 ? 
ATOM   6428  C  CA   . ASN A 1 422 ? -3.86   13.009  14.46   1   43.703  ? 428  ASN A CA   1 ? 
ATOM   6429  C  C    . ASN A 1 422 ? -3.771  13.98   13.274  1   53.83   ? 428  ASN A C    1 ? 
ATOM   6430  O  O    . ASN A 1 422 ? -2.693  14.236  12.74   1   48.357  ? 428  ASN A O    1 ? 
ATOM   6431  C  CB   . ASN A 1 422 ? -4.368  13.651  15.749  1   42.147  ? 428  ASN A CB   1 ? 
ATOM   6432  C  CG   . ASN A 1 422 ? -3.735  14.975  16.102  1   50.828  ? 428  ASN A CG   1 ? 
ATOM   6433  O  OD1  . ASN A 1 422 ? -3.119  15.645  15.252  1   39.388  ? 428  ASN A OD1  1 ? 
ATOM   6434  N  ND2  . ASN A 1 422 ? -3.95   15.396  17.348  1   48.18   ? 428  ASN A ND2  1 ? 
ATOM   6435  H  H    . ASN A 1 422 ? -1.837  12.833  14.755  1   42.477  ? 428  ASN A H    1 c 
ATOM   6436  H  HA   . ASN A 1 422 ? -4.522  12.328  14.211  1   44.746  ? 428  ASN A HA   1 c 
ATOM   6437  H  HB2  . ASN A 1 422 ? -5.334  13.779  15.673  1   44.442  ? 428  ASN A HB2  1 c 
ATOM   6438  H  HB3  . ASN A 1 422 ? -4.213  13.027  16.487  1   44.418  ? 428  ASN A HB3  1 c 
ATOM   6439  H  HD21 . ASN A 1 422 ? -3.652  16.193  17.601  1   48.958  ? 428  ASN A HD21 1 c 
ATOM   6440  H  HD22 . ASN A 1 422 ? -4.39   14.884  17.923  1   48.888  ? 428  ASN A HD22 1 c 
ATOM   6441  N  N    . LYS A 1 423 ? -4.928  14.574  12.939  1   54.929  ? 429  LYS A N    1 ? 
ATOM   6442  C  CA   . LYS A 1 423 ? -5.097  15.42   11.776  1   52.909  ? 429  LYS A CA   1 ? 
ATOM   6443  C  C    . LYS A 1 423 ? -4.581  16.845  11.962  1   55.508  ? 429  LYS A C    1 ? 
ATOM   6444  O  O    . LYS A 1 423 ? -4.402  17.552  10.97   1   55.945  ? 429  LYS A O    1 ? 
ATOM   6445  C  CB   . LYS A 1 423 ? -6.577  15.433  11.39   1   52.835  ? 429  LYS A CB   1 ? 
ATOM   6446  C  CG   . LYS A 1 423 ? -6.92   14.194  10.566  1   57.961  ? 429  LYS A CG   1 ? 
ATOM   6447  C  CD   . LYS A 1 423 ? -8.31   14.165  9.937   1   58.504  ? 429  LYS A CD   1 ? 
ATOM   6448  C  CE   . LYS A 1 423 ? -8.406  12.959  9.06    1   64.281  ? 429  LYS A CE   1 ? 
ATOM   6449  N  NZ   . LYS A 1 423 ? -9.74   12.826  8.48    1   76.171  ? 429  LYS A NZ   1 ? 
ATOM   6450  H  H    . LYS A 1 423 ? -5.653  14.436  13.477  1   53.949  ? 429  LYS A H    1 c 
ATOM   6451  H  HA   . LYS A 1 423 ? -4.59   15.011  11.029  1   53.772  ? 429  LYS A HA   1 c 
ATOM   6452  H  HB2  . LYS A 1 423 ? -7.135  15.45   12.197  1   53.986  ? 429  LYS A HB2  1 c 
ATOM   6453  H  HB3  . LYS A 1 423 ? -6.775  16.235  10.86   1   53.997  ? 429  LYS A HB3  1 c 
ATOM   6454  H  HG2  . LYS A 1 423 ? -6.253  14.108  9.85    1   56.92   ? 429  LYS A HG2  1 c 
ATOM   6455  H  HG3  . LYS A 1 423 ? -6.825  13.408  11.146  1   56.811  ? 429  LYS A HG3  1 c 
ATOM   6456  H  HD2  . LYS A 1 423 ? -8.995  14.119  10.639  1   59.669  ? 429  LYS A HD2  1 c 
ATOM   6457  H  HD3  . LYS A 1 423 ? -8.451  14.975  9.399   1   59.669  ? 429  LYS A HD3  1 c 
ATOM   6458  H  HE2  . LYS A 1 423 ? -7.75   13.016  8.346   1   65.246  ? 429  LYS A HE2  1 c 
ATOM   6459  H  HE3  . LYS A 1 423 ? -8.21   12.162  9.586   1   65.45   ? 429  LYS A HE3  1 c 
ATOM   6460  H  HZ1  . LYS A 1 423 ? -9.906  13.528  7.932   1   72.27   ? 429  LYS A HZ1  1 c 
ATOM   6461  H  HZ2  . LYS A 1 423 ? -10.361 12.808  9.139   1   72.203  ? 429  LYS A HZ2  1 c 
ATOM   6462  H  HZ3  . LYS A 1 423 ? -9.791  12.057  8.003   1   72.27   ? 429  LYS A HZ3  1 c 
ATOM   6463  N  N    . SER A 1 424 ? -4.341  17.277  13.197  1   51.822  ? 430  SER A N    1 ? 
ATOM   6464  C  CA   . SER A 1 424 ? -3.724  18.576  13.429  1   52.876  ? 430  SER A CA   1 ? 
ATOM   6465  C  C    . SER A 1 424 ? -2.198  18.494  13.393  1   43.53   ? 430  SER A C    1 ? 
ATOM   6466  O  O    . SER A 1 424 ? -1.537  19.391  13.905  1   59.542  ? 430  SER A O    1 ? 
ATOM   6467  C  CB   . SER A 1 424 ? -4.185  19.175  14.737  1   56.622  ? 430  SER A CB   1 ? 
ATOM   6468  O  OG   . SER A 1 424 ? -5.598  19.118  14.822  1   66.835  ? 430  SER A OG   1 ? 
ATOM   6469  H  H    . SER A 1 424 ? -4.568  16.759  13.914  1   52.944  ? 430  SER A H    1 c 
ATOM   6470  H  HA   . SER A 1 424 ? -4.011  19.184  12.701  1   51.52   ? 430  SER A HA   1 c 
ATOM   6471  H  HB2  . SER A 1 424 ? -3.791  18.679  15.48   1   57.918  ? 430  SER A HB2  1 c 
ATOM   6472  H  HB3  . SER A 1 424 ? -3.891  20.104  14.793  1   57.996  ? 430  SER A HB3  1 c 
ATOM   6473  H  HG   . SER A 1 424 ? -5.857  19.508  15.494  0   67.41   ? 430  SER A HG   1 c 
ATOM   6474  N  N    . GLY A 1 425 ? -1.64   17.453  12.78   1   40.534  ? 431  GLY A N    1 ? 
ATOM   6475  C  CA   . GLY A 1 425 ? -0.195  17.333  12.612  1   45.859  ? 431  GLY A CA   1 ? 
ATOM   6476  C  C    . GLY A 1 425 ? 0.585   16.815  13.836  1   44.73   ? 431  GLY A C    1 ? 
ATOM   6477  O  O    . GLY A 1 425 ? 1.802   17.013  13.912  1   40.464  ? 431  GLY A O    1 ? 
ATOM   6478  H  H    . GLY A 1 425 ? -2.17   16.783  12.458  1   42.603  ? 431  GLY A H    1 c 
ATOM   6479  H  HA2  . GLY A 1 425 ? -0.026  16.726  11.853  1   44.293  ? 431  GLY A HA2  1 c 
ATOM   6480  H  HA3  . GLY A 1 425 ? 0.161   18.215  12.361  1   44.36   ? 431  GLY A HA3  1 c 
ATOM   6481  N  N    . TRP A 1 426 ? -0.085  16.106  14.763  1   41.143  ? 432  TRP A N    1 ? 
ATOM   6482  C  CA   . TRP A 1 426 ? 0.58    15.581  15.944  1   38.636  ? 432  TRP A CA   1 ? 
ATOM   6483  C  C    . TRP A 1 426 ? 1.081   14.171  15.682  1   35.114  ? 432  TRP A C    1 ? 
ATOM   6484  O  O    . TRP A 1 426 ? 0.38    13.387  15.042  1   41.298  ? 432  TRP A O    1 ? 
ATOM   6485  C  CB   . TRP A 1 426 ? -0.339  15.57   17.167  1   38.654  ? 432  TRP A CB   1 ? 
ATOM   6486  C  CG   . TRP A 1 426 ? -0.76   16.923  17.65   1   40.964  ? 432  TRP A CG   1 ? 
ATOM   6487  C  CD1  . TRP A 1 426 ? -0.976  18.041  16.913  1   44.325  ? 432  TRP A CD1  1 ? 
ATOM   6488  C  CD2  . TRP A 1 426 ? -0.968  17.304  19.031  1   44.988  ? 432  TRP A CD2  1 ? 
ATOM   6489  N  NE1  . TRP A 1 426 ? -1.335  19.076  17.734  1   48.217  ? 432  TRP A NE1  1 ? 
ATOM   6490  C  CE2  . TRP A 1 426 ? -1.35   18.661  19.032  1   38.026  ? 432  TRP A CE2  1 ? 
ATOM   6491  C  CE3  . TRP A 1 426 ? -0.85   16.635  20.251  1   38.138  ? 432  TRP A CE3  1 ? 
ATOM   6492  C  CZ2  . TRP A 1 426 ? -1.614  19.364  20.203  1   45.499  ? 432  TRP A CZ2  1 ? 
ATOM   6493  C  CZ3  . TRP A 1 426 ? -1.107  17.329  21.415  1   44.392  ? 432  TRP A CZ3  1 ? 
ATOM   6494  C  CH2  . TRP A 1 426 ? -1.507  18.668  21.389  1   46.208  ? 432  TRP A CH2  1 ? 
ATOM   6495  H  H    . TRP A 1 426 ? -0.977  15.946  14.652  1   41.402  ? 432  TRP A H    1 c 
ATOM   6496  H  HA   . TRP A 1 426 ? 1.358   16.162  16.149  1   38.417  ? 432  TRP A HA   1 c 
ATOM   6497  H  HB2  . TRP A 1 426 ? -1.14   15.048  16.949  1   39.221  ? 432  TRP A HB2  1 c 
ATOM   6498  H  HB3  . TRP A 1 426 ? 0.123   15.106  17.897  1   39.161  ? 432  TRP A HB3  1 c 
ATOM   6499  H  HD1  . TRP A 1 426 ? -0.937  18.098  15.975  1   44.374  ? 432  TRP A HD1  1 c 
ATOM   6500  H  HE1  . TRP A 1 426 ? -1.542  19.879  17.463  1   44.654  ? 432  TRP A HE1  1 c 
ATOM   6501  H  HE3  . TRP A 1 426 ? -0.603  15.727  20.276  1   41.031  ? 432  TRP A HE3  1 c 
ATOM   6502  H  HZ2  . TRP A 1 426 ? -1.861  20.273  20.185  1   43.829  ? 432  TRP A HZ2  1 c 
ATOM   6503  H  HZ3  . TRP A 1 426 ? -1.058  16.878  22.242  1   43.24   ? 432  TRP A HZ3  1 c 
ATOM   6504  H  HH2  . TRP A 1 426 ? -1.676  19.114  22.199  1   45.548  ? 432  TRP A HH2  1 c 
ATOM   6505  N  N    . PHE A 1 427 ? 2.252   13.857  16.261  1   35.105  ? 433  PHE A N    1 ? 
ATOM   6506  C  CA   . PHE A 1 427 ? 2.876   12.533  16.207  1   31.724  ? 433  PHE A CA   1 ? 
ATOM   6507  C  C    . PHE A 1 427 ? 3.362   12.183  17.605  1   33.579  ? 433  PHE A C    1 ? 
ATOM   6508  O  O    . PHE A 1 427 ? 4.2     12.875  18.19   1   33.5    ? 433  PHE A O    1 ? 
ATOM   6509  C  CB   . PHE A 1 427 ? 4.066   12.523  15.259  1   29.219  ? 433  PHE A CB   1 ? 
ATOM   6510  C  CG   . PHE A 1 427 ? 4.614   11.196  14.795  1   29.37   ? 433  PHE A CG   1 ? 
ATOM   6511  C  CD1  . PHE A 1 427 ? 5.323   10.382  15.665  1   34.183  ? 433  PHE A CD1  1 ? 
ATOM   6512  C  CD2  . PHE A 1 427 ? 4.596   10.866  13.44   1   32.667  ? 433  PHE A CD2  1 ? 
ATOM   6513  C  CE1  . PHE A 1 427 ? 5.836   9.185   15.214  1   36.925  ? 433  PHE A CE1  1 ? 
ATOM   6514  C  CE2  . PHE A 1 427 ? 5.132   9.686   12.992  1   29.566  ? 433  PHE A CE2  1 ? 
ATOM   6515  C  CZ   . PHE A 1 427 ? 5.721   8.835   13.88   1   36.221  ? 433  PHE A CZ   1 ? 
ATOM   6516  H  H    . PHE A 1 427 ? 2.691   14.514  16.722  1   34.372  ? 433  PHE A H    1 c 
ATOM   6517  H  HA   . PHE A 1 427 ? 2.207   11.863  15.907  1   32.319  ? 433  PHE A HA   1 c 
ATOM   6518  H  HB2  . PHE A 1 427 ? 3.815   13.043  14.463  1   29.845  ? 433  PHE A HB2  1 c 
ATOM   6519  H  HB3  . PHE A 1 427 ? 4.797   13.02   15.689  1   29.865  ? 433  PHE A HB3  1 c 
ATOM   6520  H  HD1  . PHE A 1 427 ? 5.36    10.594  16.584  1   33.576  ? 433  PHE A HD1  1 c 
ATOM   6521  H  HD2  . PHE A 1 427 ? 4.148   11.433  12.832  1   31.192  ? 433  PHE A HD2  1 c 
ATOM   6522  H  HE1  . PHE A 1 427 ? 6.267   8.602   15.818  1   35.965  ? 433  PHE A HE1  1 c 
ATOM   6523  H  HE2  . PHE A 1 427 ? 5.057   9.447   12.083  1   31.895  ? 433  PHE A HE2  1 c 
ATOM   6524  H  HZ   . PHE A 1 427 ? 6.113   8.035   13.572  1   34.6    ? 433  PHE A HZ   1 c 
ATOM   6525  N  N    . LEU A 1 428 ? 2.825   11.086  18.14   1   37.856  ? 434  LEU A N    1 ? 
ATOM   6526  C  CA   . LEU A 1 428 ? 3.166   10.635  19.479  1   32.472  ? 434  LEU A CA   1 ? 
ATOM   6527  C  C    . LEU A 1 428 ? 3.878   9.3     19.326  1   35.952  ? 434  LEU A C    1 ? 
ATOM   6528  O  O    . LEU A 1 428 ? 3.327   8.411   18.68   1   32.958  ? 434  LEU A O    1 ? 
ATOM   6529  C  CB   . LEU A 1 428 ? 1.871   10.504  20.28   1   38.361  ? 434  LEU A CB   1 ? 
ATOM   6530  C  CG   . LEU A 1 428 ? 1.983   9.757   21.611  1   42.579  ? 434  LEU A CG   1 ? 
ATOM   6531  C  CD1  . LEU A 1 428 ? 2.742   10.624  22.615  1   38.099  ? 434  LEU A CD1  1 ? 
ATOM   6532  C  CD2  . LEU A 1 428 ? 0.599   9.385   22.08   1   49.5    ? 434  LEU A CD2  1 ? 
ATOM   6533  H  H    . LEU A 1 428 ? 2.224   10.598  17.654  1   35.495  ? 434  LEU A H    1 c 
ATOM   6534  H  HA   . LEU A 1 428 ? 3.765   11.293  19.91   1   35.061  ? 434  LEU A HA   1 c 
ATOM   6535  H  HB2  . LEU A 1 428 ? 1.528   11.409  20.46   1   37.833  ? 434  LEU A HB2  1 c 
ATOM   6536  H  HB3  . LEU A 1 428 ? 1.208   10.04   19.718  1   37.859  ? 434  LEU A HB3  1 c 
ATOM   6537  H  HG   . LEU A 1 428 ? 2.497   8.922   21.464  1   42.126  ? 434  LEU A HG   1 c 
ATOM   6538  H  HD11 . LEU A 1 428 ? 3.639   10.797  22.283  1   39.326  ? 434  LEU A HD11 1 c 
ATOM   6539  H  HD12 . LEU A 1 428 ? 2.798   10.161  23.468  1   39.353  ? 434  LEU A HD12 1 c 
ATOM   6540  H  HD13 . LEU A 1 428 ? 2.274   11.467  22.736  1   39.345  ? 434  LEU A HD13 1 c 
ATOM   6541  H  HD21 . LEU A 1 428 ? 0.255   8.66    21.531  1   47.224  ? 434  LEU A HD21 1 c 
ATOM   6542  H  HD22 . LEU A 1 428 ? 0.012   10.154  22.001  1   47.045  ? 434  LEU A HD22 1 c 
ATOM   6543  H  HD23 . LEU A 1 428 ? 0.636   9.098   23.008  1   47.197  ? 434  LEU A HD23 1 c 
ATOM   6544  N  N    . ALA A 1 429 ? 5.092   9.161   19.899  1   31.739  ? 435  ALA A N    1 ? 
ATOM   6545  C  CA   . ALA A 1 429 ? 5.723   7.844   19.951  1   35.442  ? 435  ALA A CA   1 ? 
ATOM   6546  C  C    . ALA A 1 429 ? 5.836   7.431   21.412  1   31.732  ? 435  ALA A C    1 ? 
ATOM   6547  O  O    . ALA A 1 429 ? 6.148   8.263   22.256  1   34.454  ? 435  ALA A O    1 ? 
ATOM   6548  C  CB   . ALA A 1 429 ? 7.077   7.813   19.289  1   33.137  ? 435  ALA A CB   1 ? 
ATOM   6549  H  H    . ALA A 1 429 ? 5.525   9.884   20.254  1   33.519  ? 435  ALA A H    1 c 
ATOM   6550  H  HA   . ALA A 1 429 ? 5.127   7.193   19.49   1   33.624  ? 435  ALA A HA   1 c 
ATOM   6551  H  HB1  . ALA A 1 429 ? 6.99    8.065   18.355  1   33.806  ? 435  ALA A HB1  1 c 
ATOM   6552  H  HB2  . ALA A 1 429 ? 7.674   8.438   19.736  1   33.806  ? 435  ALA A HB2  1 c 
ATOM   6553  H  HB3  . ALA A 1 429 ? 7.449   6.917   19.347  1   33.806  ? 435  ALA A HB3  1 c 
ATOM   6554  N  N    . THR A 1 430 ? 5.544   6.15    21.662  1   36.267  ? 436  THR A N    1 ? 
ATOM   6555  C  CA   . THR A 1 430 ? 5.56    5.553   22.986  1   39.068  ? 436  THR A CA   1 ? 
ATOM   6556  C  C    . THR A 1 430 ? 6.158   4.16    22.869  1   35.583  ? 436  THR A C    1 ? 
ATOM   6557  O  O    . THR A 1 430 ? 6.233   3.589   21.792  1   38.246  ? 436  THR A O    1 ? 
ATOM   6558  C  CB   . THR A 1 430 ? 4.17    5.501   23.632  1   48.62   ? 436  THR A CB   1 ? 
ATOM   6559  O  OG1  . THR A 1 430 ? 3.272   4.665   22.901  1   45.966  ? 436  THR A OG1  1 ? 
ATOM   6560  C  CG2  . THR A 1 430 ? 3.479   6.849   23.664  1   53.853  ? 436  THR A CG2  1 ? 
ATOM   6561  H  H    . THR A 1 430 ? 5.321   5.614   20.956  1   35.708  ? 436  THR A H    1 c 
ATOM   6562  H  HA   . THR A 1 430 ? 6.145   6.093   23.558  1   39.289  ? 436  THR A HA   1 c 
ATOM   6563  H  HB   . THR A 1 430 ? 4.251   5.161   24.555  1   47.101  ? 436  THR A HB   1 c 
ATOM   6564  H  HG1  . THR A 1 430 ? 3.17    4.965   22.115  0   45.42   ? 436  THR A HG1  1 c 
ATOM   6565  H  HG21 . THR A 1 430 ? 2.616   6.761   24.102  1   51.952  ? 436  THR A HG21 1 c 
ATOM   6566  H  HG22 . THR A 1 430 ? 3.347   7.17    22.757  1   51.824  ? 436  THR A HG22 1 c 
ATOM   6567  H  HG23 . THR A 1 430 ? 4.027   7.483   24.154  1   51.803  ? 436  THR A HG23 1 c 
ATOM   6568  N  N    . LYS A 1 431 ? 6.598   3.623   23.999  1   39.893  ? 437  LYS A N    1 ? 
ATOM   6569  C  CA   . LYS A 1 431 ? 7.181   2.296   24.021  1   38.353  ? 437  LYS A CA   1 ? 
ATOM   6570  C  C    . LYS A 1 431 ? 6.868   1.642   25.359  1   38.891  ? 437  LYS A C    1 ? 
ATOM   6571  O  O    . LYS A 1 431 ? 6.569   2.352   26.303  1   32.244  ? 437  LYS A O    1 ? 
ATOM   6572  C  CB   . LYS A 1 431 ? 8.692   2.302   23.839  1   35.504  ? 437  LYS A CB   1 ? 
ATOM   6573  C  CG   . LYS A 1 431 ? 9.454   3.056   24.883  1   37.997  ? 437  LYS A CG   1 ? 
ATOM   6574  C  CD   . LYS A 1 431 ? 10.903  3.214   24.48   1   41.304  ? 437  LYS A CD   1 ? 
ATOM   6575  C  CE   . LYS A 1 431 ? 11.588  1.903   24.207  1   38.072  ? 437  LYS A CE   1 ? 
ATOM   6576  N  NZ   . LYS A 1 431 ? 11.766  1.223   25.476  1   40.265  ? 437  LYS A NZ   1 ? 
ATOM   6577  H  H    . LYS A 1 431 ? 6.538   4.095   24.779  1   38.49   ? 437  LYS A H    1 c 
ATOM   6578  H  HA   . LYS A 1 431 ? 6.768   1.76    23.3    1   38.207  ? 437  LYS A HA   1 c 
ATOM   6579  H  HB2  . LYS A 1 431 ? 9.003   1.372   23.838  1   36.752  ? 437  LYS A HB2  1 c 
ATOM   6580  H  HB3  . LYS A 1 431 ? 8.902   2.687   22.962  1   36.738  ? 437  LYS A HB3  1 c 
ATOM   6581  H  HG2  . LYS A 1 431 ? 9.049   3.943   24.997  1   38.107  ? 437  LYS A HG2  1 c 
ATOM   6582  H  HG3  . LYS A 1 431 ? 9.4     2.575   25.737  1   38.133  ? 437  LYS A HG3  1 c 
ATOM   6583  H  HD2  . LYS A 1 431 ? 10.95   3.772   23.675  1   39.741  ? 437  LYS A HD2  1 c 
ATOM   6584  H  HD3  . LYS A 1 431 ? 11.383  3.682   25.198  1   39.774  ? 437  LYS A HD3  1 c 
ATOM   6585  H  HE2  . LYS A 1 431 ? 11.065  1.347   23.606  1   39.3    ? 437  LYS A HE2  1 c 
ATOM   6586  H  HE3  . LYS A 1 431 ? 12.459  2.061   23.803  1   39.301  ? 437  LYS A HE3  1 c 
ATOM   6587  H  HZ1  . LYS A 1 431 ? 10.974  1.114   25.901  1   39.576  ? 437  LYS A HZ1  1 c 
ATOM   6588  H  HZ2  . LYS A 1 431 ? 12.325  1.698   26.006  1   39.599  ? 437  LYS A HZ2  1 c 
ATOM   6589  H  HZ3  . LYS A 1 431 ? 12.128  0.406   25.329  1   39.6    ? 437  LYS A HZ3  1 c 
ATOM   6590  N  N    . GLY A 1 432 ? 6.795   0.301   25.337  1   39.884  ? 438  GLY A N    1 ? 
ATOM   6591  C  CA   . GLY A 1 432 ? 6.944   -0.539  26.502  1   35.218  ? 438  GLY A CA   1 ? 
ATOM   6592  C  C    . GLY A 1 432 ? 8.377   -1.042  26.594  1   40.813  ? 438  GLY A C    1 ? 
ATOM   6593  O  O    . GLY A 1 432 ? 9.287   -0.261  26.893  1   44.319  ? 438  GLY A O    1 ? 
ATOM   6594  H  H    . GLY A 1 432 ? 6.639   -0.108  24.534  1   38.557  ? 438  GLY A H    1 c 
ATOM   6595  H  HA2  . GLY A 1 432 ? 6.718   -0.024  27.312  1   37.475  ? 438  GLY A HA2  1 c 
ATOM   6596  H  HA3  . GLY A 1 432 ? 6.322   -1.301  26.438  1   37.531  ? 438  GLY A HA3  1 c 
ATOM   6597  N  N    . GLY A 1 433 ? 8.56    -2.352  26.365  1   41.24   ? 439  GLY A N    1 ? 
ATOM   6598  C  CA   . GLY A 1 433 ? 9.881   -2.948  26.208  1   40.139  ? 439  GLY A CA   1 ? 
ATOM   6599  C  C    . GLY A 1 433 ? 10.577  -3.249  27.54   1   46.036  ? 439  GLY A C    1 ? 
ATOM   6600  O  O    . GLY A 1 433 ? 9.93    -3.583  28.536  1   45.503  ? 439  GLY A O    1 ? 
ATOM   6601  H  H    . GLY A 1 433 ? 7.828   -2.898  26.309  1   40.848  ? 439  GLY A H    1 c 
ATOM   6602  H  HA2  . GLY A 1 433 ? 9.792   -3.784  25.693  1   41.664  ? 439  GLY A HA2  1 c 
ATOM   6603  H  HA3  . GLY A 1 433 ? 10.44   -2.335  25.684  1   41.723  ? 439  GLY A HA3  1 c 
ATOM   6604  N  N    . PHE A 1 434 ? 11.909  -3.152  27.534  1   45.171  ? 440  PHE A N    1 ? 
ATOM   6605  C  CA   . PHE A 1 434 ? 12.743  -3.594  28.649  1   47.155  ? 440  PHE A CA   1 ? 
ATOM   6606  C  C    . PHE A 1 434 ? 14.091  -2.862  28.642  1   41.842  ? 440  PHE A C    1 ? 
ATOM   6607  O  O    . PHE A 1 434 ? 14.497  -2.294  27.635  1   44.866  ? 440  PHE A O    1 ? 
ATOM   6608  C  CB   . PHE A 1 434 ? 12.889  -5.116  28.558  1   45.312  ? 440  PHE A CB   1 ? 
ATOM   6609  C  CG   . PHE A 1 434 ? 13.522  -5.615  27.267  1   42.721  ? 440  PHE A CG   1 ? 
ATOM   6610  C  CD1  . PHE A 1 434 ? 12.782  -5.674  26.094  1   52.961  ? 440  PHE A CD1  1 ? 
ATOM   6611  C  CD2  . PHE A 1 434 ? 14.837  -6.059  27.242  1   50.079  ? 440  PHE A CD2  1 ? 
ATOM   6612  C  CE1  . PHE A 1 434 ? 13.361  -6.113  24.912  1   56.458  ? 440  PHE A CE1  1 ? 
ATOM   6613  C  CE2  . PHE A 1 434 ? 15.413  -6.524  26.063  1   42.225  ? 440  PHE A CE2  1 ? 
ATOM   6614  C  CZ   . PHE A 1 434 ? 14.68   -6.537  24.904  1   51.84   ? 440  PHE A CZ   1 ? 
ATOM   6615  H  H    . PHE A 1 434 ? 12.321  -2.794  26.801  1   45.702  ? 440  PHE A H    1 c 
ATOM   6616  H  HA   . PHE A 1 434 ? 12.275  -3.374  29.494  1   45.415  ? 440  PHE A HA   1 c 
ATOM   6617  H  HB2  . PHE A 1 434 ? 13.434  -5.422  29.317  1   45.152  ? 440  PHE A HB2  1 c 
ATOM   6618  H  HB3  . PHE A 1 434 ? 11.998  -5.52   28.65   1   45.135  ? 440  PHE A HB3  1 c 
ATOM   6619  H  HD1  . PHE A 1 434 ? 11.888  -5.371  26.091  1   50.999  ? 440  PHE A HD1  1 c 
ATOM   6620  H  HD2  . PHE A 1 434 ? 15.349  -6.037  28.034  1   46.488  ? 440  PHE A HD2  1 c 
ATOM   6621  H  HE1  . PHE A 1 434 ? 12.852  -6.139  24.117  1   54.292  ? 440  PHE A HE1  1 c 
ATOM   6622  H  HE2  . PHE A 1 434 ? 16.314  -6.807  26.057  1   46.182  ? 440  PHE A HE2  1 c 
ATOM   6623  H  HZ   . PHE A 1 434 ? 15.068  -6.857  24.105  1   50.347  ? 440  PHE A HZ   1 c 
ATOM   6624  N  N    . ASN A 1 435 ? 14.788  -2.846  29.779  1   41.783  ? 441  ASN A N    1 ? 
ATOM   6625  C  CA   . ASN A 1 435 ? 16.023  -2.075  29.888  1   39.818  ? 441  ASN A CA   1 ? 
ATOM   6626  C  C    . ASN A 1 435 ? 17.277  -2.931  29.608  1   46.677  ? 441  ASN A C    1 ? 
ATOM   6627  O  O    . ASN A 1 435 ? 18.261  -2.901  30.34   1   41.993  ? 441  ASN A O    1 ? 
ATOM   6628  C  CB   . ASN A 1 435 ? 16.014  -1.313  31.197  1   37.535  ? 441  ASN A CB   1 ? 
ATOM   6629  C  CG   . ASN A 1 435 ? 15.053  -0.155  31.12   1   42.206  ? 441  ASN A CG   1 ? 
ATOM   6630  O  OD1  . ASN A 1 435 ? 14.643  0.23    30.015  1   52.577  ? 441  ASN A OD1  1 ? 
ATOM   6631  N  ND2  . ASN A 1 435 ? 14.735  0.44    32.26   1   43.917  ? 441  ASN A ND2  1 ? 
ATOM   6632  H  H    . ASN A 1 435 ? 14.493  -3.323  30.502  1   41.367  ? 441  ASN A H    1 c 
ATOM   6633  H  HA   . ASN A 1 435 ? 15.998  -1.397  29.181  1   40.993  ? 441  ASN A HA   1 c 
ATOM   6634  H  HB2  . ASN A 1 435 ? 15.746  -1.911  31.923  1   39.102  ? 441  ASN A HB2  1 c 
ATOM   6635  H  HB3  . ASN A 1 435 ? 16.913  -0.978  31.389  1   39.116  ? 441  ASN A HB3  1 c 
ATOM   6636  H  HD21 . ASN A 1 435 ? 14.239  1.176   32.251  1   43.436  ? 441  ASN A HD21 1 c 
ATOM   6637  H  HD22 . ASN A 1 435 ? 15.016  0.103   33.031  1   43.353  ? 441  ASN A HD22 1 c 
ATOM   6638  N  N    . ASN A 1 436 ? 17.244  -3.686  28.511  1   50.219  ? 442  ASN A N    1 ? 
ATOM   6639  C  CA   . ASN A 1 436 ? 18.443  -4.233  27.909  1   54.369  ? 442  ASN A CA   1 ? 
ATOM   6640  C  C    . ASN A 1 436 ? 18.222  -4.319  26.399  1   55.176  ? 442  ASN A C    1 ? 
ATOM   6641  O  O    . ASN A 1 436 ? 18.609  -5.276  25.742  1   58.069  ? 442  ASN A O    1 ? 
ATOM   6642  C  CB   . ASN A 1 436 ? 18.794  -5.578  28.526  1   57.385  ? 442  ASN A CB   1 ? 
ATOM   6643  C  CG   . ASN A 1 436 ? 20.138  -6.096  28.076  1   52.745  ? 442  ASN A CG   1 ? 
ATOM   6644  O  OD1  . ASN A 1 436 ? 21.147  -5.403  28.207  1   48.064  ? 442  ASN A OD1  1 ? 
ATOM   6645  N  ND2  . ASN A 1 436 ? 20.173  -7.324  27.586  1   56.472  ? 442  ASN A ND2  1 ? 
ATOM   6646  H  H    . ASN A 1 436 ? 16.437  -3.882  28.13   1   50.076  ? 442  ASN A H    1 c 
ATOM   6647  H  HA   . ASN A 1 436 ? 19.191  -3.617  28.084  1   54.066  ? 442  ASN A HA   1 c 
ATOM   6648  H  HB2  . ASN A 1 436 ? 18.798  -5.489  29.5    1   55.596  ? 442  ASN A HB2  1 c 
ATOM   6649  H  HB3  . ASN A 1 436 ? 18.103  -6.227  28.287  1   55.599  ? 442  ASN A HB3  1 c 
ATOM   6650  H  HD21 . ASN A 1 436 ? 20.939  -7.656  27.286  1   55.243  ? 442  ASN A HD21 1 c 
ATOM   6651  H  HD22 . ASN A 1 436 ? 19.436  -7.817  27.556  1   55.301  ? 442  ASN A HD22 1 c 
ATOM   6652  N  N    . GLU A 1 437 ? 17.582  -3.288  25.858  1   48.72   ? 443  GLU A N    1 ? 
ATOM   6653  C  CA   . GLU A 1 437 ? 17.348  -3.173  24.431  1   48.013  ? 443  GLU A CA   1 ? 
ATOM   6654  C  C    . GLU A 1 437 ? 18.665  -2.775  23.765  1   41.768  ? 443  GLU A C    1 ? 
ATOM   6655  O  O    . GLU A 1 437 ? 19.563  -2.263  24.433  1   40.474  ? 443  GLU A O    1 ? 
ATOM   6656  C  CB   . GLU A 1 437 ? 16.209  -2.152  24.249  1   44.529  ? 443  GLU A CB   1 ? 
ATOM   6657  C  CG   . GLU A 1 437 ? 14.815  -2.743  24.46   1   41.271  ? 443  GLU A CG   1 ? 
ATOM   6658  C  CD   . GLU A 1 437 ? 13.625  -1.785  24.567  1   43.915  ? 443  GLU A CD   1 ? 
ATOM   6659  O  OE1  . GLU A 1 437 ? 12.49   -2.299  24.453  1   43.935  ? 443  GLU A OE1  1 ? 
ATOM   6660  O  OE2  . GLU A 1 437 ? 13.764  -0.579  24.852  1   41.454  ? 443  GLU A OE2  1 ? 
ATOM   6661  H  H    . GLU A 1 437 ? 17.29   -2.615  26.402  1   49.958  ? 443  GLU A H    1 c 
ATOM   6662  H  HA   . GLU A 1 437 ? 17.061  -4.055  24.083  1   46.41   ? 443  GLU A HA   1 c 
ATOM   6663  H  HB2  . GLU A 1 437 ? 16.342  -1.409  24.874  1   44.569  ? 443  GLU A HB2  1 c 
ATOM   6664  H  HB3  . GLU A 1 437 ? 16.257  -1.788  23.341  1   44.549  ? 443  GLU A HB3  1 c 
ATOM   6665  H  HG2  . GLU A 1 437 ? 14.632  -3.362  23.722  1   42.596  ? 443  GLU A HG2  1 c 
ATOM   6666  H  HG3  . GLU A 1 437 ? 14.834  -3.287  25.276  1   42.605  ? 443  GLU A HG3  1 c 
ATOM   6667  N  N    . SER A 1 438 ? 18.764  -2.973  22.444  1   43.628  ? 444  SER A N    1 ? 
ATOM   6668  C  CA   . SER A 1 438 ? 19.897  -2.463  21.68   1   47.172  ? 444  SER A CA   1 ? 
ATOM   6669  C  C    . SER A 1 438 ? 20.149  -0.993  22.015  1   50.575  ? 444  SER A C    1 ? 
ATOM   6670  O  O    . SER A 1 438 ? 19.218  -0.184  22.049  1   49.864  ? 444  SER A O    1 ? 
ATOM   6671  C  CB   . SER A 1 438 ? 19.684  -2.599  20.193  1   52.992  ? 444  SER A CB   1 ? 
ATOM   6672  O  OG   . SER A 1 438 ? 19.682  -3.955  19.78   1   67.055  ? 444  SER A OG   1 ? 
ATOM   6673  H  H    . SER A 1 438 ? 18.108  -3.437  22.008  1   44.022  ? 444  SER A H    1 c 
ATOM   6674  H  HA   . SER A 1 438 ? 20.7    -2.987  21.932  1   48.088  ? 444  SER A HA   1 c 
ATOM   6675  H  HB2  . SER A 1 438 ? 18.832  -2.188  19.953  1   54.591  ? 444  SER A HB2  1 c 
ATOM   6676  H  HB3  . SER A 1 438 ? 20.393  -2.12   19.722  1   54.574  ? 444  SER A HB3  1 c 
ATOM   6677  H  HG   . SER A 1 438 ? 19.593  -4.002  18.984  0   66.3    ? 444  SER A HG   1 c 
ATOM   6678  N  N    . HIS A 1 439 ? 21.42   -0.664  22.256  1   48.468  ? 445  HIS A N    1 ? 
ATOM   6679  C  CA   . HIS A 1 439 ? 21.859  0.676   22.625  1   48.153  ? 445  HIS A CA   1 ? 
ATOM   6680  C  C    . HIS A 1 439 ? 20.947  1.249   23.696  1   47.197  ? 445  HIS A C    1 ? 
ATOM   6681  O  O    . HIS A 1 439 ? 20.703  2.447   23.714  1   42.135  ? 445  HIS A O    1 ? 
ATOM   6682  C  CB   . HIS A 1 439 ? 21.897  1.628   21.42   1   50.245  ? 445  HIS A CB   1 ? 
ATOM   6683  C  CG   . HIS A 1 439 ? 22.562  1.066   20.223  1   52.845  ? 445  HIS A CG   1 ? 
ATOM   6684  N  ND1  . HIS A 1 439 ? 23.935  0.992   20.113  1   60.507  ? 445  HIS A ND1  1 ? 
ATOM   6685  C  CD2  . HIS A 1 439 ? 22.057  0.532   19.095  1   67.037  ? 445  HIS A CD2  1 ? 
ATOM   6686  C  CE1  . HIS A 1 439 ? 24.247  0.43    18.945  1   60.745  ? 445  HIS A CE1  1 ? 
ATOM   6687  N  NE2  . HIS A 1 439 ? 23.124  0.15    18.306  1   67.206  ? 445  HIS A NE2  1 ? 
ATOM   6688  H  H    . HIS A 1 439 ? 22.056  -1.317  22.185  1   48.87   ? 445  HIS A H    1 c 
ATOM   6689  H  HA   . HIS A 1 439 ? 22.771  0.603   23.001  1   48.407  ? 445  HIS A HA   1 c 
ATOM   6690  H  HB2  . HIS A 1 439 ? 20.976  1.874   21.183  1   50.275  ? 445  HIS A HB2  1 c 
ATOM   6691  H  HB3  . HIS A 1 439 ? 22.365  2.448   21.684  1   50.241  ? 445  HIS A HB3  1 c 
ATOM   6692  H  HD1  . HIS A 1 439 ? 24.528  1.288   20.757  0   61.81   ? 445  HIS A HD1  1 c 
ATOM   6693  H  HD2  . HIS A 1 439 ? 21.152  0.442   18.873  1   63.377  ? 445  HIS A HD2  1 c 
ATOM   6694  H  HE1  . HIS A 1 439 ? 25.119  0.273   18.626  1   62.087  ? 445  HIS A HE1  1 c 
ATOM   6695  H  HE2  . HIS A 1 439 ? 23.139  -0.17   17.512  0   68.09   ? 445  HIS A HE2  1 c 
ATOM   6696  N  N    . ASN A 1 440 ? 20.566  0.391   24.652  1   50.555  ? 446  ASN A N    1 ? 
ATOM   6697  C  CA   . ASN A 1 440 ? 19.56   0.68    25.656  1   39.608  ? 446  ASN A CA   1 ? 
ATOM   6698  C  C    . ASN A 1 440 ? 19.688  2.082   26.234  1   38.556  ? 446  ASN A C    1 ? 
ATOM   6699  O  O    . ASN A 1 440 ? 20.727  2.456   26.773  1   42.383  ? 446  ASN A O    1 ? 
ATOM   6700  C  CB   . ASN A 1 440 ? 19.635  -0.326  26.795  1   39.365  ? 446  ASN A CB   1 ? 
ATOM   6701  C  CG   . ASN A 1 440 ? 18.521  -0.147  27.785  1   34.444  ? 446  ASN A CG   1 ? 
ATOM   6702  O  OD1  . ASN A 1 440 ? 17.376  -0.527  27.507  1   34.982  ? 446  ASN A OD1  1 ? 
ATOM   6703  N  ND2  . ASN A 1 440 ? 18.84   0.379   28.966  1   39.317  ? 446  ASN A ND2  1 ? 
ATOM   6704  H  H    . ASN A 1 440 ? 20.977  -0.425  24.685  1   46.944  ? 446  ASN A H    1 c 
ATOM   6705  H  HA   . ASN A 1 440 ? 18.674  0.588   25.238  1   41.246  ? 446  ASN A HA   1 c 
ATOM   6706  H  HB2  . ASN A 1 440 ? 19.594  -1.23   26.431  1   38.286  ? 446  ASN A HB2  1 c 
ATOM   6707  H  HB3  . ASN A 1 440 ? 20.493  -0.225  27.255  1   38.239  ? 446  ASN A HB3  1 c 
ATOM   6708  H  HD21 . ASN A 1 440 ? 18.256  0.345   29.634  1   37.729  ? 446  ASN A HD21 1 c 
ATOM   6709  H  HD22 . ASN A 1 440 ? 19.631  0.763   29.086  1   37.758  ? 446  ASN A HD22 1 c 
ATOM   6710  N  N    . HIS A 1 441 ? 18.539  2.767   26.263  1   37.637  ? 447  HIS A N    1 ? 
ATOM   6711  C  CA   . HIS A 1 441 ? 18.216  3.731   27.307  1   39.561  ? 447  HIS A CA   1 ? 
ATOM   6712  C  C    . HIS A 1 441 ? 17.235  3.103   28.319  1   41.263  ? 447  HIS A C    1 ? 
ATOM   6713  O  O    . HIS A 1 441 ? 16.469  2.172   27.989  1   35.594  ? 447  HIS A O    1 ? 
ATOM   6714  C  CB   . HIS A 1 441 ? 17.643  5.007   26.665  1   39.721  ? 447  HIS A CB   1 ? 
ATOM   6715  C  CG   . HIS A 1 441 ? 18.679  5.851   25.984  1   46.353  ? 447  HIS A CG   1 ? 
ATOM   6716  N  ND1  . HIS A 1 441 ? 18.394  7.031   25.337  1   40.664  ? 447  HIS A ND1  1 ? 
ATOM   6717  C  CD2  . HIS A 1 441 ? 20.014  5.661   25.825  1   50.411  ? 447  HIS A CD2  1 ? 
ATOM   6718  C  CE1  . HIS A 1 441 ? 19.525  7.563   24.874  1   44.679  ? 447  HIS A CE1  1 ? 
ATOM   6719  N  NE2  . HIS A 1 441 ? 20.518  6.732   25.136  1   46.002  ? 447  HIS A NE2  1 ? 
ATOM   6720  H  H    . HIS A 1 441 ? 17.929  2.631   25.596  1   38.337  ? 447  HIS A H    1 c 
ATOM   6721  H  HA   . HIS A 1 441 ? 19.048  3.964   27.788  1   39.592  ? 447  HIS A HA   1 c 
ATOM   6722  H  HB2  . HIS A 1 441 ? 16.961  4.749   26.009  1   41.094  ? 447  HIS A HB2  1 c 
ATOM   6723  H  HB3  . HIS A 1 441 ? 17.205  5.541   27.362  1   41.126  ? 447  HIS A HB3  1 c 
ATOM   6724  H  HD1  . HIS A 1 441 ? 17.617  7.424   25.286  0   41.39   ? 447  HIS A HD1  1 c 
ATOM   6725  H  HD2  . HIS A 1 441 ? 20.519  4.943   26.151  1   48.221  ? 447  HIS A HD2  1 c 
ATOM   6726  H  HE1  . HIS A 1 441 ? 19.59   8.364   24.384  1   44.052  ? 447  HIS A HE1  1 c 
ATOM   6727  H  HE2  . HIS A 1 441 ? 21.373  6.846   24.888  0   45.5    ? 447  HIS A HE2  1 c 
ATOM   6728  N  N    . ASN A 1 442 ? 17.236  3.66    29.549  1   38.351  ? 448  ASN A N    1 ? 
ATOM   6729  C  CA   . ASN A 1 442 ? 16.246  3.313   30.564  1   38.719  ? 448  ASN A CA   1 ? 
ATOM   6730  C  C    . ASN A 1 442 ? 14.999  4.191   30.374  1   39.037  ? 448  ASN A C    1 ? 
ATOM   6731  O  O    . ASN A 1 442 ? 14.935  5.303   30.895  1   37.693  ? 448  ASN A O    1 ? 
ATOM   6732  C  CB   . ASN A 1 442 ? 16.818  3.472   31.973  1   34.468  ? 448  ASN A CB   1 ? 
ATOM   6733  C  CG   . ASN A 1 442 ? 17.874  2.453   32.346  1   36.631  ? 448  ASN A CG   1 ? 
ATOM   6734  O  OD1  . ASN A 1 442 ? 17.952  1.375   31.751  1   42.405  ? 448  ASN A OD1  1 ? 
ATOM   6735  N  ND2  . ASN A 1 442 ? 18.614  2.726   33.417  1   41.686  ? 448  ASN A ND2  1 ? 
ATOM   6736  H  H    . ASN A 1 442 ? 17.877  4.277   29.757  1   39.061  ? 448  ASN A H    1 c 
ATOM   6737  H  HA   . ASN A 1 442 ? 15.995  2.372   30.447  1   37.992  ? 448  ASN A HA   1 c 
ATOM   6738  H  HB2  . ASN A 1 442 ? 17.205  4.367   32.054  1   35.946  ? 448  ASN A HB2  1 c 
ATOM   6739  H  HB3  . ASN A 1 442 ? 16.084  3.41    32.617  1   35.916  ? 448  ASN A HB3  1 c 
ATOM   6740  H  HD21 . ASN A 1 442 ? 19.254  2.166   33.667  1   40.059  ? 448  ASN A HD21 1 c 
ATOM   6741  H  HD22 . ASN A 1 442 ? 18.466  3.467   33.882  1   39.987  ? 448  ASN A HD22 1 c 
ATOM   6742  N  N    . ASP A 1 443 ? 14.004  3.678   29.643  1   36.728  ? 449  ASP A N    1 ? 
ATOM   6743  C  CA   . ASP A 1 443 ? 12.965  4.528   29.069  1   40.243  ? 449  ASP A CA   1 ? 
ATOM   6744  C  C    . ASP A 1 443 ? 11.658  3.766   28.856  1   32.792  ? 449  ASP A C    1 ? 
ATOM   6745  O  O    . ASP A 1 443 ? 10.909  4.119   27.958  1   31.423  ? 449  ASP A O    1 ? 
ATOM   6746  C  CB   . ASP A 1 443 ? 13.407  5.08    27.715  1   40.585  ? 449  ASP A CB   1 ? 
ATOM   6747  C  CG   . ASP A 1 443 ? 13.767  3.985   26.728  1   41.391  ? 449  ASP A CG   1 ? 
ATOM   6748  O  OD1  . ASP A 1 443 ? 13.442  2.793   27.037  1   41.834  ? 449  ASP A OD1  1 ? 
ATOM   6749  O  OD2  . ASP A 1 443 ? 14.354  4.322   25.683  1   37.413  ? 449  ASP A OD2  1 ? 
ATOM   6750  H  H    . ASP A 1 443 ? 13.976  2.778   29.488  1   37.972  ? 449  ASP A H    1 c 
ATOM   6751  H  HA   . ASP A 1 443 ? 12.798  5.281   29.679  1   38.113  ? 449  ASP A HA   1 c 
ATOM   6752  H  HB2  . ASP A 1 443 ? 12.7    5.638   27.332  1   40.503  ? 449  ASP A HB2  1 c 
ATOM   6753  H  HB3  . ASP A 1 443 ? 14.197  5.644   27.848  1   40.654  ? 449  ASP A HB3  1 c 
ATOM   6754  N  N    . VAL A 1 444 ? 11.344  2.786   29.723  1   36.72   ? 450  VAL A N    1 ? 
ATOM   6755  C  CA   . VAL A 1 444 ? 10.116  2.002   29.598  1   32.967  ? 450  VAL A CA   1 ? 
ATOM   6756  C  C    . VAL A 1 444 ? 8.913   2.905   29.885  1   33.899  ? 450  VAL A C    1 ? 
ATOM   6757  O  O    . VAL A 1 444 ? 8.833   3.535   30.947  1   34.241  ? 450  VAL A O    1 ? 
ATOM   6758  C  CB   . VAL A 1 444 ? 10.169  0.768   30.526  1   33.624  ? 450  VAL A CB   1 ? 
ATOM   6759  C  CG1  . VAL A 1 444 ? 8.864   -0.015  30.534  1   37.129  ? 450  VAL A CG1  1 ? 
ATOM   6760  C  CG2  . VAL A 1 444 ? 11.318  -0.171  30.168  1   35.491  ? 450  VAL A CG2  1 ? 
ATOM   6761  H  H    . VAL A 1 444 ? 11.905  2.612   30.424  1   34.951  ? 450  VAL A H    1 c 
ATOM   6762  H  HA   . VAL A 1 444 ? 10.053  1.686   28.676  1   33.958  ? 450  VAL A HA   1 c 
ATOM   6763  H  HB   . VAL A 1 444 ? 10.326  1.099   31.442  1   34.514  ? 450  VAL A HB   1 c 
ATOM   6764  H  HG11 . VAL A 1 444 ? 8.607   -0.224  29.62   1   36.111  ? 450  VAL A HG11 1 c 
ATOM   6765  H  HG12 . VAL A 1 444 ? 8.166   0.516   30.953  1   36.059  ? 450  VAL A HG12 1 c 
ATOM   6766  H  HG13 . VAL A 1 444 ? 8.983   -0.841  31.033  1   36.059  ? 450  VAL A HG13 1 c 
ATOM   6767  H  HG21 . VAL A 1 444 ? 11.291  -0.954  30.744  1   34.963  ? 450  VAL A HG21 1 c 
ATOM   6768  H  HG22 . VAL A 1 444 ? 12.164  0.29    30.291  1   35.033  ? 450  VAL A HG22 1 c 
ATOM   6769  H  HG23 . VAL A 1 444 ? 11.234  -0.449  29.24   1   34.957  ? 450  VAL A HG23 1 c 
ATOM   6770  N  N    . GLY A 1 445 ? 8.007   2.979   28.895  1   35.248  ? 451  GLY A N    1 ? 
ATOM   6771  C  CA   . GLY A 1 445 ? 6.802   3.779   28.981  1   34.954  ? 451  GLY A CA   1 ? 
ATOM   6772  C  C    . GLY A 1 445 ? 6.998   5.229   28.557  1   36.281  ? 451  GLY A C    1 ? 
ATOM   6773  O  O    . GLY A 1 445 ? 6.035   5.996   28.62   1   40.189  ? 451  GLY A O    1 ? 
ATOM   6774  H  H    . GLY A 1 445 ? 8.154   2.503   28.129  1   34.834  ? 451  GLY A H    1 c 
ATOM   6775  H  HA2  . GLY A 1 445 ? 6.109   3.37    28.416  1   35.302  ? 451  GLY A HA2  1 c 
ATOM   6776  H  HA3  . GLY A 1 445 ? 6.475   3.759   29.91   1   35.343  ? 451  GLY A HA3  1 c 
ATOM   6777  N  N    . THR A 1 446 ? 8.218   5.621   28.144  1   36.185  ? 452  THR A N    1 ? 
ATOM   6778  C  CA   . THR A 1 446 ? 8.478   6.996   27.727  1   35.915  ? 452  THR A CA   1 ? 
ATOM   6779  C  C    . THR A 1 446 ? 7.556   7.388   26.566  1   37.144  ? 452  THR A C    1 ? 
ATOM   6780  O  O    . THR A 1 446 ? 6.938   6.534   25.926  1   33.831  ? 452  THR A O    1 ? 
ATOM   6781  C  CB   . THR A 1 446 ? 9.966   7.176   27.379  1   34.53   ? 452  THR A CB   1 ? 
ATOM   6782  O  OG1  . THR A 1 446 ? 10.171  8.573   27.391  1   31.048  ? 452  THR A OG1  1 ? 
ATOM   6783  C  CG2  . THR A 1 446 ? 10.395  6.651   26.024  1   34.599  ? 452  THR A CG2  1 ? 
ATOM   6784  H  H    . THR A 1 446 ? 8.902   5.016   28.115  1   36.092  ? 452  THR A H    1 c 
ATOM   6785  H  HA   . THR A 1 446 ? 8.273   7.581   28.489  1   35.894  ? 452  THR A HA   1 c 
ATOM   6786  H  HB   . THR A 1 446 ? 10.522  6.76    28.079  1   34.069  ? 452  THR A HB   1 c 
ATOM   6787  H  HG1  . THR A 1 446 ? 9.647   8.928   26.804  0   31.54   ? 452  THR A HG1  1 c 
ATOM   6788  H  HG21 . THR A 1 446 ? 11.353  6.771   25.918  1   34.625  ? 452  THR A HG21 1 c 
ATOM   6789  H  HG22 . THR A 1 446 ? 9.931   7.139   25.323  1   34.604  ? 452  THR A HG22 1 c 
ATOM   6790  H  HG23 . THR A 1 446 ? 10.178  5.707   25.958  1   34.598  ? 452  THR A HG23 1 c 
ATOM   6791  N  N    . PHE A 1 447 ? 7.425   8.7     26.331  1   35.105  ? 453  PHE A N    1 ? 
ATOM   6792  C  CA   . PHE A 1 447 ? 6.873   9.179   25.078  1   33.686  ? 453  PHE A CA   1 ? 
ATOM   6793  C  C    . PHE A 1 447 ? 7.689   10.346  24.531  1   31.924  ? 453  PHE A C    1 ? 
ATOM   6794  O  O    . PHE A 1 447 ? 8.456   11.003  25.231  1   30.724  ? 453  PHE A O    1 ? 
ATOM   6795  C  CB   . PHE A 1 447 ? 5.42    9.614   25.189  1   31.635  ? 453  PHE A CB   1 ? 
ATOM   6796  C  CG   . PHE A 1 447 ? 5.239   10.943  25.903  1   29.816  ? 453  PHE A CG   1 ? 
ATOM   6797  C  CD1  . PHE A 1 447 ? 5.434   11.041  27.28   1   32.675  ? 453  PHE A CD1  1 ? 
ATOM   6798  C  CD2  . PHE A 1 447 ? 4.882   12.089  25.208  1   31.244  ? 453  PHE A CD2  1 ? 
ATOM   6799  C  CE1  . PHE A 1 447 ? 5.259   12.254  27.937  1   32.213  ? 453  PHE A CE1  1 ? 
ATOM   6800  C  CE2  . PHE A 1 447 ? 4.69    13.303  25.871  1   31.347  ? 453  PHE A CE2  1 ? 
ATOM   6801  C  CZ   . PHE A 1 447 ? 4.868   13.38   27.231  1   32.603  ? 453  PHE A CZ   1 ? 
ATOM   6802  H  H    . PHE A 1 447 ? 7.688   9.305   26.964  1   35.246  ? 453  PHE A H    1 c 
ATOM   6803  H  HA   . PHE A 1 447 ? 6.922   8.438   24.422  1   33.272  ? 453  PHE A HA   1 c 
ATOM   6804  H  HB2  . PHE A 1 447 ? 5.043   9.683   24.284  1   31.691  ? 453  PHE A HB2  1 c 
ATOM   6805  H  HB3  . PHE A 1 447 ? 4.923   8.921   25.675  1   31.78   ? 453  PHE A HB3  1 c 
ATOM   6806  H  HD1  . PHE A 1 447 ? 5.68    10.274  27.772  1   31.911  ? 453  PHE A HD1  1 c 
ATOM   6807  H  HD2  . PHE A 1 447 ? 4.735   12.038  24.277  1   30.969  ? 453  PHE A HD2  1 c 
ATOM   6808  H  HE1  . PHE A 1 447 ? 5.384   12.304  28.871  1   32.379  ? 453  PHE A HE1  1 c 
ATOM   6809  H  HE2  . PHE A 1 447 ? 4.44    14.071  25.383  1   31.613  ? 453  PHE A HE2  1 c 
ATOM   6810  H  HZ   . PHE A 1 447 ? 4.763   14.206  27.676  1   32.198  ? 453  PHE A HZ   1 c 
ATOM   6811  N  N    . SER A 1 448 ? 7.482   10.579  23.241  1   34.635  ? 454  SER A N    1 ? 
ATOM   6812  C  CA   . SER A 1 448 ? 7.991   11.739  22.541  1   32.288  ? 454  SER A CA   1 ? 
ATOM   6813  C  C    . SER A 1 448 ? 6.802   12.318  21.776  1   33.198  ? 454  SER A C    1 ? 
ATOM   6814  O  O    . SER A 1 448 ? 6.04    11.58   21.178  1   29.606  ? 454  SER A O    1 ? 
ATOM   6815  C  CB   . SER A 1 448 ? 9.082   11.325  21.573  1   34.469  ? 454  SER A CB   1 ? 
ATOM   6816  O  OG   . SER A 1 448 ? 10.073  10.443  22.109  1   33.358  ? 454  SER A OG   1 ? 
ATOM   6817  H  H    . SER A 1 448 ? 6.993   9.971   22.764  1   33.431  ? 454  SER A H    1 c 
ATOM   6818  H  HA   . SER A 1 448 ? 8.337   12.403  23.188  1   33.248  ? 454  SER A HA   1 c 
ATOM   6819  H  HB2  . SER A 1 448 ? 8.667   10.893  20.802  1   33.695  ? 454  SER A HB2  1 c 
ATOM   6820  H  HB3  . SER A 1 448 ? 9.527   12.129  21.245  1   33.697  ? 454  SER A HB3  1 c 
ATOM   6821  H  HG   . SER A 1 448 ? 10.637  10.274  21.502  0   33.8    ? 454  SER A HG   1 c 
ATOM   6822  N  N    . LEU A 1 449 ? 6.609   13.623  21.801  1   31.212  ? 455  LEU A N    1 ? 
ATOM   6823  C  CA   . LEU A 1 449 ? 5.529   14.267  21.065  1   28.916  ? 455  LEU A CA   1 ? 
ATOM   6824  C  C    . LEU A 1 449 ? 6.119   15.319  20.118  1   32.149  ? 455  LEU A C    1 ? 
ATOM   6825  O  O    . LEU A 1 449 ? 6.938   16.136  20.542  1   34.231  ? 455  LEU A O    1 ? 
ATOM   6826  C  CB   . LEU A 1 449 ? 4.541   14.94   22.008  1   31.381  ? 455  LEU A CB   1 ? 
ATOM   6827  C  CG   . LEU A 1 449 ? 3.398   15.715  21.331  1   32.374  ? 455  LEU A CG   1 ? 
ATOM   6828  C  CD1  . LEU A 1 449 ? 2.38    14.813  20.638  1   32.939  ? 455  LEU A CD1  1 ? 
ATOM   6829  C  CD2  . LEU A 1 449 ? 2.7     16.63   22.304  1   37.259  ? 455  LEU A CD2  1 ? 
ATOM   6830  H  H    . LEU A 1 449 ? 7.171   14.146  22.296  1   31.157  ? 455  LEU A H    1 c 
ATOM   6831  H  HA   . LEU A 1 449 ? 5.056   13.582  20.531  1   30.439  ? 455  LEU A HA   1 c 
ATOM   6832  H  HB2  . LEU A 1 449 ? 4.146   14.247  22.586  1   31.022  ? 455  LEU A HB2  1 c 
ATOM   6833  H  HB3  . LEU A 1 449 ? 5.041   15.563  22.584  1   31.047  ? 455  LEU A HB3  1 c 
ATOM   6834  H  HG   . LEU A 1 449 ? 3.798   16.292  20.631  1   33.162  ? 455  LEU A HG   1 c 
ATOM   6835  H  HD11 . LEU A 1 449 ? 2.831   14.261  19.978  1   32.778  ? 455  LEU A HD11 1 c 
ATOM   6836  H  HD12 . LEU A 1 449 ? 1.708   15.36   20.198  1   32.845  ? 455  LEU A HD12 1 c 
ATOM   6837  H  HD13 . LEU A 1 449 ? 1.951   14.242  21.297  1   32.787  ? 455  LEU A HD13 1 c 
ATOM   6838  H  HD21 . LEU A 1 449 ? 3.336   17.273  22.66   1   35.732  ? 455  LEU A HD21 1 c 
ATOM   6839  H  HD22 . LEU A 1 449 ? 2.329   16.106  23.034  1   35.732  ? 455  LEU A HD22 1 c 
ATOM   6840  H  HD23 . LEU A 1 449 ? 1.983   17.103  21.849  1   35.732  ? 455  LEU A HD23 1 c 
ATOM   6841  N  N    . TYR A 1 450 ? 5.595   15.342  18.883  1   32.719  ? 456  TYR A N    1 ? 
ATOM   6842  C  CA   . TYR A 1 450 ? 5.974   16.267  17.829  1   32.85   ? 456  TYR A CA   1 ? 
ATOM   6843  C  C    . TYR A 1 450 ? 4.692   16.917  17.329  1   33.75   ? 456  TYR A C    1 ? 
ATOM   6844  O  O    . TYR A 1 450 ? 3.688   16.241  17.144  1   36.402  ? 456  TYR A O    1 ? 
ATOM   6845  C  CB   . TYR A 1 450 ? 6.635   15.527  16.645  1   31.043  ? 456  TYR A CB   1 ? 
ATOM   6846  C  CG   . TYR A 1 450 ? 7.775   14.571  16.976  1   31.957  ? 456  TYR A CG   1 ? 
ATOM   6847  C  CD1  . TYR A 1 450 ? 7.526   13.329  17.534  1   29.993  ? 456  TYR A CD1  1 ? 
ATOM   6848  C  CD2  . TYR A 1 450 ? 9.111   14.909  16.762  1   34.689  ? 456  TYR A CD2  1 ? 
ATOM   6849  C  CE1  . TYR A 1 450 ? 8.556   12.43   17.807  1   34.404  ? 456  TYR A CE1  1 ? 
ATOM   6850  C  CE2  . TYR A 1 450 ? 10.15   14.031  17.064  1   32.571  ? 456  TYR A CE2  1 ? 
ATOM   6851  C  CZ   . TYR A 1 450 ? 9.873   12.795  17.608  1   33.095  ? 456  TYR A CZ   1 ? 
ATOM   6852  O  OH   . TYR A 1 450 ? 10.843  11.906  17.946  1   38.933  ? 456  TYR A OH   1 ? 
ATOM   6853  H  H    . TYR A 1 450 ? 4.949   14.726  18.688  1   32.572  ? 456  TYR A H    1 c 
ATOM   6854  H  HA   . TYR A 1 450 ? 6.591   16.956  18.187  1   32.676  ? 456  TYR A HA   1 c 
ATOM   6855  H  HB2  . TYR A 1 450 ? 5.936   15.022  16.174  1   31.651  ? 456  TYR A HB2  1 c 
ATOM   6856  H  HB3  . TYR A 1 450 ? 6.972   16.203  16.015  1   31.652  ? 456  TYR A HB3  1 c 
ATOM   6857  H  HD1  . TYR A 1 450 ? 6.634   13.06   17.678  1   31.493  ? 456  TYR A HD1  1 c 
ATOM   6858  H  HD2  . TYR A 1 450 ? 9.317   15.754  16.395  1   33.511  ? 456  TYR A HD2  1 c 
ATOM   6859  H  HE1  . TYR A 1 450 ? 8.357   11.595  18.197  1   33.052  ? 456  TYR A HE1  1 c 
ATOM   6860  H  HE2  . TYR A 1 450 ? 11.043  14.289  16.915  1   33.252  ? 456  TYR A HE2  1 c 
ATOM   6861  H  HH   . TYR A 1 450 ? 11.042  11.412  17.284  0   37.58   ? 456  TYR A HH   1 c 
ATOM   6862  N  N    . VAL A 1 451 ? 4.754   18.199  16.997  1   32.082  ? 457  VAL A N    1 ? 
ATOM   6863  C  CA   . VAL A 1 451 ? 3.601   18.885  16.461  1   35.675  ? 457  VAL A CA   1 ? 
ATOM   6864  C  C    . VAL A 1 451 ? 4.049   19.624  15.198  1   36.733  ? 457  VAL A C    1 ? 
ATOM   6865  O  O    . VAL A 1 451 ? 4.93    20.478  15.269  1   33.015  ? 457  VAL A O    1 ? 
ATOM   6866  C  CB   . VAL A 1 451 ? 2.963   19.818  17.511  1   40.561  ? 457  VAL A CB   1 ? 
ATOM   6867  C  CG1  . VAL A 1 451 ? 1.763   20.576  16.941  1   43.839  ? 457  VAL A CG1  1 ? 
ATOM   6868  C  CG2  . VAL A 1 451 ? 2.54    19.056  18.768  1   38.06   ? 457  VAL A CG2  1 ? 
ATOM   6869  H  H    . VAL A 1 451 ? 5.535   18.661  17.107  1   33.275  ? 457  VAL A H    1 c 
ATOM   6870  H  HA   . VAL A 1 451 ? 2.937   18.217  16.205  1   35.992  ? 457  VAL A HA   1 c 
ATOM   6871  H  HB   . VAL A 1 451 ? 3.648   20.478  17.77   1   39.711  ? 457  VAL A HB   1 c 
ATOM   6872  H  HG11 . VAL A 1 451 ? 1.134   19.944  16.554  1   42.842  ? 457  VAL A HG11 1 c 
ATOM   6873  H  HG12 . VAL A 1 451 ? 2.064   21.195  16.255  1   42.812  ? 457  VAL A HG12 1 c 
ATOM   6874  H  HG13 . VAL A 1 451 ? 1.325   21.073  17.653  1   42.815  ? 457  VAL A HG13 1 c 
ATOM   6875  H  HG21 . VAL A 1 451 ? 2.093   19.664  19.381  1   38.794  ? 457  VAL A HG21 1 c 
ATOM   6876  H  HG22 . VAL A 1 451 ? 3.326   18.682  19.202  1   38.738  ? 457  VAL A HG22 1 c 
ATOM   6877  H  HG23 . VAL A 1 451 ? 1.933   18.338  18.524  1   38.773  ? 457  VAL A HG23 1 c 
ATOM   6878  N  N    . ASN A 1 452 ? 3.404   19.297  14.06   1   38.556  ? 458  ASN A N    1 ? 
ATOM   6879  C  CA   . ASN A 1 452 ? 3.789   19.798  12.734  1   42.733  ? 458  ASN A CA   1 ? 
ATOM   6880  C  C    . ASN A 1 452 ? 5.296   19.598  12.504  1   36.056  ? 458  ASN A C    1 ? 
ATOM   6881  O  O    . ASN A 1 452 ? 6.023   20.506  12.084  1   39.795  ? 458  ASN A O    1 ? 
ATOM   6882  C  CB   . ASN A 1 452 ? 3.316   21.232  12.529  1   39.085  ? 458  ASN A CB   1 ? 
ATOM   6883  C  CG   . ASN A 1 452 ? 1.811   21.326  12.594  1   48.49   ? 458  ASN A CG   1 ? 
ATOM   6884  O  OD1  . ASN A 1 452 ? 1.098   20.488  12.028  1   46.837  ? 458  ASN A OD1  1 ? 
ATOM   6885  N  ND2  . ASN A 1 452 ? 1.307   22.297  13.341  1   46.72   ? 458  ASN A ND2  1 ? 
ATOM   6886  H  H    . ASN A 1 452 ? 2.685   18.735  14.113  1   38.981  ? 458  ASN A H    1 c 
ATOM   6887  H  HA   . ASN A 1 452 ? 3.32    19.247  12.07   1   40.077  ? 458  ASN A HA   1 c 
ATOM   6888  H  HB2  . ASN A 1 452 ? 3.707   21.803  13.22   1   41.969  ? 458  ASN A HB2  1 c 
ATOM   6889  H  HB3  . ASN A 1 452 ? 3.623   21.553  11.658  1   41.911  ? 458  ASN A HB3  1 c 
ATOM   6890  H  HD21 . ASN A 1 452 ? 0.539   22.17   13.772  1   47.243  ? 458  ASN A HD21 1 c 
ATOM   6891  H  HD22 . ASN A 1 452 ? 1.733   23.074  13.404  1   47.197  ? 458  ASN A HD22 1 c 
ATOM   6892  N  N    . THR A 1 453 ? 5.744   18.39   12.84   1   35.627  ? 459  THR A N    1 ? 
ATOM   6893  C  CA   . THR A 1 453 ? 7.07    17.85   12.599  1   35.609  ? 459  THR A CA   1 ? 
ATOM   6894  C  C    . THR A 1 453 ? 8.065   18.449  13.587  1   39.988  ? 459  THR A C    1 ? 
ATOM   6895  O  O    . THR A 1 453 ? 9.176   17.945  13.686  1   43.44   ? 459  THR A O    1 ? 
ATOM   6896  C  CB   . THR A 1 453 ? 7.543   18.033  11.15   1   40.031  ? 459  THR A CB   1 ? 
ATOM   6897  O  OG1  . THR A 1 453 ? 8.052   19.355  11.036  1   38.018  ? 459  THR A OG1  1 ? 
ATOM   6898  C  CG2  . THR A 1 453 ? 6.463   17.74   10.128  1   35.792  ? 459  THR A CG2  1 ? 
ATOM   6899  H  H    . THR A 1 453 ? 5.15    17.837  13.26   1   35.795  ? 459  THR A H    1 c 
ATOM   6900  H  HA   . THR A 1 453 ? 7.024   16.886  12.773  1   37.143  ? 459  THR A HA   1 c 
ATOM   6901  H  HB   . THR A 1 453 ? 8.282   17.399  10.986  1   37.995  ? 459  THR A HB   1 c 
ATOM   6902  H  HG1  . THR A 1 453 ? 7.4     19.915  11.237  0   37.92   ? 459  THR A HG1  1 c 
ATOM   6903  H  HG21 . THR A 1 453 ? 6.856   17.713  9.239   1   36.997  ? 459  THR A HG21 1 c 
ATOM   6904  H  HG22 . THR A 1 453 ? 5.785   18.435  10.158  1   36.985  ? 459  THR A HG22 1 c 
ATOM   6905  H  HG23 . THR A 1 453 ? 6.053   16.88   10.326  1   36.996  ? 459  THR A HG23 1 c 
ATOM   6906  N  N    . ILE A 1 454 ? 7.643   19.444  14.38   1   37.419  ? 460  ILE A N    1 ? 
ATOM   6907  C  CA   . ILE A 1 454 ? 8.529   20.04   15.355  1   31.292  ? 460  ILE A CA   1 ? 
ATOM   6908  C  C    . ILE A 1 454 ? 8.493   19.223  16.644  1   38.232  ? 460  ILE A C    1 ? 
ATOM   6909  O  O    . ILE A 1 454 ? 7.42    19.007  17.197  1   34.692  ? 460  ILE A O    1 ? 
ATOM   6910  C  CB   . ILE A 1 454 ? 8.163   21.52   15.539  1   37.791  ? 460  ILE A CB   1 ? 
ATOM   6911  C  CG1  . ILE A 1 454 ? 8.41    22.278  14.194  1   37      ? 460  ILE A CG1  1 ? 
ATOM   6912  C  CG2  . ILE A 1 454 ? 8.957   22.13   16.71   1   36.074  ? 460  ILE A CG2  1 ? 
ATOM   6913  C  CD1  . ILE A 1 454 ? 7.831   23.66   14.13   1   46.94   ? 460  ILE A CD1  1 ? 
ATOM   6914  H  H    . ILE A 1 454 ? 6.785   19.751  14.32   1   36.489  ? 460  ILE A H    1 c 
ATOM   6915  H  HA   . ILE A 1 454 ? 9.434   20.006  14.996  1   34.903  ? 460  ILE A HA   1 c 
ATOM   6916  H  HB   . ILE A 1 454 ? 7.211   21.576  15.751  1   36.015  ? 460  ILE A HB   1 c 
ATOM   6917  H  HG12 . ILE A 1 454 ? 9.376   22.338  14.044  1   39.299  ? 460  ILE A HG12 1 c 
ATOM   6918  H  HG13 . ILE A 1 454 ? 8.03    21.75   13.463  1   39.252  ? 460  ILE A HG13 1 c 
ATOM   6919  H  HG21 . ILE A 1 454 ? 8.802   23.089  16.745  1   36.661  ? 460  ILE A HG21 1 c 
ATOM   6920  H  HG22 . ILE A 1 454 ? 9.906   21.962  16.583  1   36.59   ? 460  ILE A HG22 1 c 
ATOM   6921  H  HG23 . ILE A 1 454 ? 8.667   21.729  17.546  1   36.597  ? 460  ILE A HG23 1 c 
ATOM   6922  H  HD11 . ILE A 1 454 ? 6.86    23.608  14.203  1   43.719  ? 460  ILE A HD11 1 c 
ATOM   6923  H  HD12 . ILE A 1 454 ? 8.07    24.074  13.279  1   43.694  ? 460  ILE A HD12 1 c 
ATOM   6924  H  HD13 . ILE A 1 454 ? 8.182   24.2    14.862  1   43.607  ? 460  ILE A HD13 1 c 
ATOM   6925  N  N    . PRO A 1 455 ? 9.651   18.711  17.15   1   36.778  ? 461  PRO A N    1 ? 
ATOM   6926  C  CA   . PRO A 1 455 ? 9.703   18.09   18.461  1   32.887  ? 461  PRO A CA   1 ? 
ATOM   6927  C  C    . PRO A 1 455 ? 9.277   19.057  19.568  1   33.581  ? 461  PRO A C    1 ? 
ATOM   6928  O  O    . PRO A 1 455 ? 9.741   20.193  19.629  1   31.018  ? 461  PRO A O    1 ? 
ATOM   6929  C  CB   . PRO A 1 455 ? 11.172  17.608  18.599  1   31.334  ? 461  PRO A CB   1 ? 
ATOM   6930  C  CG   . PRO A 1 455 ? 11.694  17.518  17.162  1   32.385  ? 461  PRO A CG   1 ? 
ATOM   6931  C  CD   . PRO A 1 455 ? 10.943  18.625  16.456  1   36.497  ? 461  PRO A CD   1 ? 
ATOM   6932  H  HA   . PRO A 1 455 ? 9.102   17.304  18.459  1   33.44   ? 461  PRO A HA   1 c 
ATOM   6933  H  HB2  . PRO A 1 455 ? 11.704  18.251  19.125  1   31.921  ? 461  PRO A HB2  1 c 
ATOM   6934  H  HB3  . PRO A 1 455 ? 11.212  16.728  19.042  1   31.938  ? 461  PRO A HB3  1 c 
ATOM   6935  H  HG2  . PRO A 1 455 ? 12.661  17.67   17.126  1   33.031  ? 461  PRO A HG2  1 c 
ATOM   6936  H  HG3  . PRO A 1 455 ? 11.491  16.645  16.765  1   33.035  ? 461  PRO A HG3  1 c 
ATOM   6937  H  HD2  . PRO A 1 455 ? 11.433  19.475  16.522  1   35.596  ? 461  PRO A HD2  1 c 
ATOM   6938  H  HD3  . PRO A 1 455 ? 10.819  18.405  15.508  1   35.606  ? 461  PRO A HD3  1 c 
ATOM   6939  N  N    . VAL A 1 456 ? 8.439   18.583  20.499  1   30.98   ? 462  VAL A N    1 ? 
ATOM   6940  C  CA   . VAL A 1 456 ? 7.981   19.459  21.567  1   34.77   ? 462  VAL A CA   1 ? 
ATOM   6941  C  C    . VAL A 1 456 ? 8.225   18.794  22.92   1   35.123  ? 462  VAL A C    1 ? 
ATOM   6942  O  O    . VAL A 1 456 ? 8.719   19.433  23.823  1   37.118  ? 462  VAL A O    1 ? 
ATOM   6943  C  CB   . VAL A 1 456 ? 6.531   19.97   21.453  1   39.639  ? 462  VAL A CB   1 ? 
ATOM   6944  C  CG1  . VAL A 1 456 ? 6.403   21.053  20.403  1   42.27   ? 462  VAL A CG1  1 ? 
ATOM   6945  C  CG2  . VAL A 1 456 ? 5.521   18.847  21.203  1   42.501  ? 462  VAL A CG2  1 ? 
ATOM   6946  H  H    . VAL A 1 456 ? 8.146   17.719  20.464  1   32.462  ? 462  VAL A H    1 c 
ATOM   6947  H  HA   . VAL A 1 456 ? 8.553   20.25   21.544  1   34.917  ? 462  VAL A HA   1 c 
ATOM   6948  H  HB   . VAL A 1 456 ? 6.303   20.379  22.321  1   39.646  ? 462  VAL A HB   1 c 
ATOM   6949  H  HG11 . VAL A 1 456 ? 6.69    20.706  19.542  1   41.472  ? 462  VAL A HG11 1 c 
ATOM   6950  H  HG12 . VAL A 1 456 ? 6.959   21.811  20.649  1   41.472  ? 462  VAL A HG12 1 c 
ATOM   6951  H  HG13 . VAL A 1 456 ? 5.475   21.338  20.343  1   41.472  ? 462  VAL A HG13 1 c 
ATOM   6952  H  HG21 . VAL A 1 456 ? 4.627   19.224  21.14   1   41.565  ? 462  VAL A HG21 1 c 
ATOM   6953  H  HG22 . VAL A 1 456 ? 5.551   18.211  21.936  1   41.487  ? 462  VAL A HG22 1 c 
ATOM   6954  H  HG23 . VAL A 1 456 ? 5.738   18.395  20.371  1   41.494  ? 462  VAL A HG23 1 c 
ATOM   6955  N  N    . LEU A 1 457 ? 7.916   17.508  23.062  1   35.176  ? 463  LEU A N    1 ? 
ATOM   6956  C  CA   . LEU A 1 457 ? 8.463   16.744  24.172  1   36.259  ? 463  LEU A CA   1 ? 
ATOM   6957  C  C    . LEU A 1 457 ? 9.372   15.657  23.618  1   34.382  ? 463  LEU A C    1 ? 
ATOM   6958  O  O    . LEU A 1 457 ? 8.947   14.816  22.815  1   32.637  ? 463  LEU A O    1 ? 
ATOM   6959  C  CB   . LEU A 1 457 ? 7.306   16.203  25.019  1   37.841  ? 463  LEU A CB   1 ? 
ATOM   6960  C  CG   . LEU A 1 457 ? 6.544   17.351  25.692  1   39.151  ? 463  LEU A CG   1 ? 
ATOM   6961  C  CD1  . LEU A 1 457 ? 5.089   17.275  25.535  1   42.856  ? 463  LEU A CD1  1 ? 
ATOM   6962  C  CD2  . LEU A 1 457 ? 6.914   17.469  27.144  1   40.227  ? 463  LEU A CD2  1 ? 
ATOM   6963  H  H    . LEU A 1 457 ? 7.362   17.095  22.465  1   35.434  ? 463  LEU A H    1 c 
ATOM   6964  H  HA   . LEU A 1 457 ? 9.008   17.352  24.73   1   35.954  ? 463  LEU A HA   1 c 
ATOM   6965  H  HB2  . LEU A 1 457 ? 6.69    15.705  24.434  1   37.8    ? 463  LEU A HB2  1 c 
ATOM   6966  H  HB3  . LEU A 1 457 ? 7.672   15.607  25.713  1   37.8    ? 463  LEU A HB3  1 c 
ATOM   6967  H  HG   . LEU A 1 457 ? 6.83    18.195  25.258  1   39.717  ? 463  LEU A HG   1 c 
ATOM   6968  H  HD11 . LEU A 1 457 ? 4.863   17.266  24.59   1   41.686  ? 463  LEU A HD11 1 c 
ATOM   6969  H  HD12 . LEU A 1 457 ? 4.678   18.047  25.959  1   41.673  ? 463  LEU A HD12 1 c 
ATOM   6970  H  HD13 . LEU A 1 457 ? 4.761   16.462  25.954  1   41.692  ? 463  LEU A HD13 1 c 
ATOM   6971  H  HD21 . LEU A 1 457 ? 7.864   17.659  27.222  1   39.933  ? 463  LEU A HD21 1 c 
ATOM   6972  H  HD22 . LEU A 1 457 ? 6.713   16.635  27.597  1   39.941  ? 463  LEU A HD22 1 c 
ATOM   6973  H  HD23 . LEU A 1 457 ? 6.406   18.19   27.553  1   39.942  ? 463  LEU A HD23 1 c 
ATOM   6974  N  N    . ILE A 1 458 ? 10.628  15.673  24.091  1   33.574  ? 464  ILE A N    1 ? 
ATOM   6975  C  CA   . ILE A 1 458 ? 11.727  15.175  23.287  1   30.752  ? 464  ILE A CA   1 ? 
ATOM   6976  C  C    . ILE A 1 458 ? 12.475  14.122  24.079  1   31.912  ? 464  ILE A C    1 ? 
ATOM   6977  O  O    . ILE A 1 458 ? 12.272  13.96   25.303  1   31.44   ? 464  ILE A O    1 ? 
ATOM   6978  C  CB   . ILE A 1 458 ? 12.628  16.346  22.852  1   32.185  ? 464  ILE A CB   1 ? 
ATOM   6979  C  CG1  . ILE A 1 458 ? 13.439  16.906  24.037  1   32.592  ? 464  ILE A CG1  1 ? 
ATOM   6980  C  CG2  . ILE A 1 458 ? 11.777  17.437  22.199  1   29.996  ? 464  ILE A CG2  1 ? 
ATOM   6981  C  CD1  . ILE A 1 458 ? 14.525  17.9    23.655  1   33.843  ? 464  ILE A CD1  1 ? 
ATOM   6982  H  H    . ILE A 1 458 ? 10.799  15.994  24.929  1   33.146  ? 464  ILE A H    1 c 
ATOM   6983  H  HA   . ILE A 1 458 ? 11.36   14.757  22.484  1   31.793  ? 464  ILE A HA   1 c 
ATOM   6984  H  HB   . ILE A 1 458 ? 13.259  16.011  22.185  1   31.572  ? 464  ILE A HB   1 c 
ATOM   6985  H  HG12 . ILE A 1 458 ? 12.822  17.342  24.659  1   32.81   ? 464  ILE A HG12 1 c 
ATOM   6986  H  HG13 . ILE A 1 458 ? 13.859  16.159  24.511  1   32.846  ? 464  ILE A HG13 1 c 
ATOM   6987  H  HG21 . ILE A 1 458 ? 12.357  18.094  21.778  1   30.659  ? 464  ILE A HG21 1 c 
ATOM   6988  H  HG22 . ILE A 1 458 ? 11.232  17.876  22.875  1   30.646  ? 464  ILE A HG22 1 c 
ATOM   6989  H  HG23 . ILE A 1 458 ? 11.199  17.04   21.526  1   30.634  ? 464  ILE A HG23 1 c 
ATOM   6990  H  HD11 . ILE A 1 458 ? 15.123  17.495  22.999  1   33.461  ? 464  ILE A HD11 1 c 
ATOM   6991  H  HD12 . ILE A 1 458 ? 15.035  18.147  24.449  1   33.461  ? 464  ILE A HD12 1 c 
ATOM   6992  H  HD13 . ILE A 1 458 ? 14.117  18.699  23.271  1   33.432  ? 464  ILE A HD13 1 c 
ATOM   6993  N  N    . ASP A 1 459 ? 13.239  13.352  23.299  1   30.013  ? 465  ASP A N    1 ? 
ATOM   6994  C  CA   . ASP A 1 459 ? 14.104  12.282  23.765  1   32.291  ? 465  ASP A CA   1 ? 
ATOM   6995  C  C    . ASP A 1 459 ? 15.483  12.637  23.217  1   37.141  ? 465  ASP A C    1 ? 
ATOM   6996  O  O    . ASP A 1 459 ? 15.631  12.758  22      1   35.628  ? 465  ASP A O    1 ? 
ATOM   6997  C  CB   . ASP A 1 459 ? 13.543  10.936  23.338  1   29.833  ? 465  ASP A CB   1 ? 
ATOM   6998  C  CG   . ASP A 1 459 ? 14.068  9.657   23.976  1   31.53   ? 465  ASP A CG   1 ? 
ATOM   6999  O  OD1  . ASP A 1 459 ? 15.167  9.685   24.548  1   30.113  ? 465  ASP A OD1  1 ? 
ATOM   7000  O  OD2  . ASP A 1 459 ? 13.395  8.6     23.844  1   31.776  ? 465  ASP A OD2  1 ? 
ATOM   7001  H  H    . ASP A 1 459 ? 13.216  13.511  22.399  1   31.008  ? 465  ASP A H    1 c 
ATOM   7002  H  HA   . ASP A 1 459 ? 14.134  12.309  24.748  1   32.278  ? 465  ASP A HA   1 c 
ATOM   7003  H  HB2  . ASP A 1 459 ? 12.575  10.958  23.491  1   30.767  ? 465  ASP A HB2  1 c 
ATOM   7004  H  HB3  . ASP A 1 459 ? 13.68   10.853  22.371  1   30.771  ? 465  ASP A HB3  1 c 
ATOM   7005  N  N    . ALA A 1 460 ? 16.466  12.847  24.116  1   39.555  ? 466  ALA A N    1 ? 
ATOM   7006  C  CA   . ALA A 1 460 ? 17.716  13.538  23.79   1   37.725  ? 466  ALA A CA   1 ? 
ATOM   7007  C  C    . ALA A 1 460 ? 18.559  12.771  22.767  1   41.126  ? 466  ALA A C    1 ? 
ATOM   7008  O  O    . ALA A 1 460 ? 19.152  13.353  21.851  1   35.641  ? 466  ALA A O    1 ? 
ATOM   7009  C  CB   . ALA A 1 460 ? 18.514  13.74   25.066  1   44.183  ? 466  ALA A CB   1 ? 
ATOM   7010  H  H    . ALA A 1 460 ? 16.352  12.539  24.969  1   38.486  ? 466  ALA A H    1 c 
ATOM   7011  H  HA   . ALA A 1 460 ? 17.488  14.428  23.402  1   39.811  ? 466  ALA A HA   1 c 
ATOM   7012  H  HB1  . ALA A 1 460 ? 17.996  14.269  25.696  1   42.177  ? 466  ALA A HB1  1 c 
ATOM   7013  H  HB2  . ALA A 1 460 ? 18.719  12.877  25.464  1   42.17   ? 466  ALA A HB2  1 c 
ATOM   7014  H  HB3  . ALA A 1 460 ? 19.343  14.205  24.863  1   42.17   ? 466  ALA A HB3  1 c 
ATOM   7015  N  N    . GLY A 1 461 ? 18.677  11.457  22.977  1   40.545  ? 467  GLY A N    1 ? 
ATOM   7016  C  CA   . GLY A 1 461 ? 19.363  10.598  22.031  1   40.696  ? 467  GLY A CA   1 ? 
ATOM   7017  C  C    . GLY A 1 461 ? 20.871  10.513  22.287  1   39.829  ? 467  GLY A C    1 ? 
ATOM   7018  O  O    . GLY A 1 461 ? 21.316  10.611  23.424  1   39.379  ? 467  GLY A O    1 ? 
ATOM   7019  H  H    . GLY A 1 461 ? 18.325  11.086  23.735  1   40.688  ? 467  GLY A H    1 c 
ATOM   7020  H  HA2  . GLY A 1 461 ? 18.975  9.695   22.083  1   40.399  ? 467  GLY A HA2  1 c 
ATOM   7021  H  HA3  . GLY A 1 461 ? 19.205  10.939  21.121  1   40.378  ? 467  GLY A HA3  1 c 
ATOM   7022  N  N    . VAL A 1 462 ? 21.627  10.365  21.195  1   38.136  ? 468  VAL A N    1 ? 
ATOM   7023  C  CA   . VAL A 1 462 ? 22.991  9.854   21.192  1   43.288  ? 468  VAL A CA   1 ? 
ATOM   7024  C  C    . VAL A 1 462 ? 23.99   10.994  21.38   1   42.905  ? 468  VAL A C    1 ? 
ATOM   7025  O  O    . VAL A 1 462 ? 23.947  11.984  20.661  1   39.181  ? 468  VAL A O    1 ? 
ATOM   7026  C  CB   . VAL A 1 462 ? 23.25   9.088   19.88   1   43.695  ? 468  VAL A CB   1 ? 
ATOM   7027  C  CG1  . VAL A 1 462 ? 23.321  10.019  18.658  1   46.546  ? 468  VAL A CG1  1 ? 
ATOM   7028  C  CG2  . VAL A 1 462 ? 24.498  8.214   19.986  1   46.13   ? 468  VAL A CG2  1 ? 
ATOM   7029  H  H    . VAL A 1 462 ? 21.261  10.604  20.393  1   39.78   ? 468  VAL A H    1 c 
ATOM   7030  H  HA   . VAL A 1 462 ? 23.085  9.231   21.936  1   42.244  ? 468  VAL A HA   1 c 
ATOM   7031  H  HB   . VAL A 1 462 ? 22.481  8.487   19.745  1   44.571  ? 468  VAL A HB   1 c 
ATOM   7032  H  HG11 . VAL A 1 462 ? 24.176  10.482  18.648  1   45.614  ? 468  VAL A HG11 1 c 
ATOM   7033  H  HG12 . VAL A 1 462 ? 22.601  10.671  18.699  1   45.586  ? 468  VAL A HG12 1 c 
ATOM   7034  H  HG13 . VAL A 1 462 ? 23.231  9.492   17.845  1   45.658  ? 468  VAL A HG13 1 c 
ATOM   7035  H  HG21 . VAL A 1 462 ? 24.638  7.746   19.146  1   45.403  ? 468  VAL A HG21 1 c 
ATOM   7036  H  HG22 . VAL A 1 462 ? 24.382  7.568   20.699  1   45.42   ? 468  VAL A HG22 1 c 
ATOM   7037  H  HG23 . VAL A 1 462 ? 25.271  8.771   20.178  1   45.393  ? 468  VAL A HG23 1 c 
ATOM   7038  N  N    . GLY A 1 463 ? 24.904  10.795  22.332  1   43.949  ? 469  GLY A N    1 ? 
ATOM   7039  C  CA   . GLY A 1 463 ? 26.035  11.678  22.579  1   45.473  ? 469  GLY A CA   1 ? 
ATOM   7040  C  C    . GLY A 1 463 ? 27.345  11.039  22.093  1   47.559  ? 469  GLY A C    1 ? 
ATOM   7041  O  O    . GLY A 1 463 ? 27.361  9.916   21.579  1   48.071  ? 469  GLY A O    1 ? 
ATOM   7042  H  H    . GLY A 1 463 ? 24.817  10.058  22.865  1   44.015  ? 469  GLY A H    1 c 
ATOM   7043  H  HA2  . GLY A 1 463 ? 25.891  12.535  22.112  1   45.499  ? 469  GLY A HA2  1 c 
ATOM   7044  H  HA3  . GLY A 1 463 ? 26.096  11.863  23.545  1   45.544  ? 469  GLY A HA3  1 c 
ATOM   7045  N  N    . THR A 1 464 ? 28.452  11.77   22.278  1   46.46   ? 470  THR A N    1 ? 
ATOM   7046  C  CA   . THR A 1 464 ? 29.773  11.297  21.897  1   48.83   ? 470  THR A CA   1 ? 
ATOM   7047  C  C    . THR A 1 464 ? 30.166  10.122  22.788  1   45.776  ? 470  THR A C    1 ? 
ATOM   7048  O  O    . THR A 1 464 ? 29.951  10.142  24.002  1   41.568  ? 470  THR A O    1 ? 
ATOM   7049  C  CB   . THR A 1 464 ? 30.794  12.431  21.986  1   47.606  ? 470  THR A CB   1 ? 
ATOM   7050  O  OG1  . THR A 1 464 ? 30.313  13.471  21.133  1   44.153  ? 470  THR A OG1  1 ? 
ATOM   7051  C  CG2  . THR A 1 464 ? 32.163  11.966  21.518  1   46.572  ? 470  THR A CG2  1 ? 
ATOM   7052  H  H    . THR A 1 464 ? 28.378  12.594  22.665  1   47.248  ? 470  THR A H    1 c 
ATOM   7053  H  HA   . THR A 1 464 ? 29.732  10.989  20.965  1   47.558  ? 470  THR A HA   1 c 
ATOM   7054  H  HB   . THR A 1 464 ? 30.852  12.764  22.913  1   46.935  ? 470  THR A HB   1 c 
ATOM   7055  H  HG1  . THR A 1 464 ? 30.266  13.139  20.278  0   44.3    ? 470  THR A HG1  1 c 
ATOM   7056  H  HG21 . THR A 1 464 ? 32.759  12.731  21.447  1   46.874  ? 470  THR A HG21 1 c 
ATOM   7057  H  HG22 . THR A 1 464 ? 32.081  11.539  20.648  1   46.874  ? 470  THR A HG22 1 c 
ATOM   7058  H  HG23 . THR A 1 464 ? 32.529  11.332  22.157  1   46.869  ? 470  THR A HG23 1 c 
ATOM   7059  N  N    . TYR A 1 465 ? 30.722  9.078   22.174  1   45.443  ? 471  TYR A N    1 ? 
ATOM   7060  C  CA   . TYR A 1 465 ? 31.157  7.93    22.957  1   54.348  ? 471  TYR A CA   1 ? 
ATOM   7061  C  C    . TYR A 1 465 ? 32.334  8.337   23.837  1   47.913  ? 471  TYR A C    1 ? 
ATOM   7062  O  O    . TYR A 1 465 ? 33.208  9.084   23.39   1   46.889  ? 471  TYR A O    1 ? 
ATOM   7063  C  CB   . TYR A 1 465 ? 31.512  6.78    22.018  1   55.297  ? 471  TYR A CB   1 ? 
ATOM   7064  C  CG   . TYR A 1 465 ? 30.35   6.164   21.259  1   58.111  ? 471  TYR A CG   1 ? 
ATOM   7065  C  CD1  . TYR A 1 465 ? 29.024  6.316   21.669  1   58.891  ? 471  TYR A CD1  1 ? 
ATOM   7066  C  CD2  . TYR A 1 465 ? 30.603  5.375   20.147  1   59.253  ? 471  TYR A CD2  1 ? 
ATOM   7067  C  CE1  . TYR A 1 465 ? 27.989  5.707   20.974  1   59.485  ? 471  TYR A CE1  1 ? 
ATOM   7068  C  CE2  . TYR A 1 465 ? 29.58   4.77    19.44   1   67.691  ? 471  TYR A CE2  1 ? 
ATOM   7069  C  CZ   . TYR A 1 465 ? 28.274  4.933   19.86   1   64.015  ? 471  TYR A CZ   1 ? 
ATOM   7070  O  OH   . TYR A 1 465 ? 27.329  4.309   19.12   1   54.701  ? 471  TYR A OH   1 ? 
ATOM   7071  H  H    . TYR A 1 465 ? 30.835  9.075   21.267  1   47.504  ? 471  TYR A H    1 c 
ATOM   7072  H  HA   . TYR A 1 465 ? 30.408  7.644   23.542  1   51.515  ? 471  TYR A HA   1 c 
ATOM   7073  H  HB2  . TYR A 1 465 ? 32.172  7.108   21.367  1   55.642  ? 471  TYR A HB2  1 c 
ATOM   7074  H  HB3  . TYR A 1 465 ? 31.948  6.076   22.547  1   55.652  ? 471  TYR A HB3  1 c 
ATOM   7075  H  HD1  . TYR A 1 465 ? 28.825  6.834   22.431  1   58.789  ? 471  TYR A HD1  1 c 
ATOM   7076  H  HD2  . TYR A 1 465 ? 31.494  5.254   19.86   1   60.822  ? 471  TYR A HD2  1 c 
ATOM   7077  H  HE1  . TYR A 1 465 ? 27.097  5.822   21.254  1   60.332  ? 471  TYR A HE1  1 c 
ATOM   7078  H  HE2  . TYR A 1 465 ? 29.772  4.243   18.683  1   64.566  ? 471  TYR A HE2  1 c 
ATOM   7079  H  HH   . TYR A 1 465 ? 26.992  4.854   18.536  0   55.77   ? 471  TYR A HH   1 c 
ATOM   7080  N  N    . THR A 1 466 ? 32.295  7.877   25.099  1   58.501  ? 472  THR A N    1 ? 
ATOM   7081  C  CA   . THR A 1 466 ? 33.423  7.962   26.022  1   55.096  ? 472  THR A CA   1 ? 
ATOM   7082  C  C    . THR A 1 466 ? 33.746  6.573   26.587  1   62.349  ? 472  THR A C    1 ? 
ATOM   7083  O  O    . THR A 1 466 ? 33.191  5.547   26.175  1   52.682  ? 472  THR A O    1 ? 
ATOM   7084  C  CB   . THR A 1 466 ? 33.156  8.968   27.148  1   55.213  ? 472  THR A CB   1 ? 
ATOM   7085  O  OG1  . THR A 1 466 ? 32.208  8.305   27.989  1   55.825  ? 472  THR A OG1  1 ? 
ATOM   7086  C  CG2  . THR A 1 466 ? 32.739  10.338  26.636  1   50.687  ? 472  THR A CG2  1 ? 
ATOM   7087  H  H    . THR A 1 466 ? 31.524  7.491   25.399  1   54.992  ? 472  THR A H    1 c 
ATOM   7088  H  HA   . THR A 1 466 ? 34.205  8.274   25.517  1   56.924  ? 472  THR A HA   1 c 
ATOM   7089  H  HB   . THR A 1 466 ? 33.99   9.1     27.659  1   54.66   ? 472  THR A HB   1 c 
ATOM   7090  H  HG1  . THR A 1 466 ? 31.507  8.139   27.544  0   56.98   ? 472  THR A HG1  1 c 
ATOM   7091  H  HG21 . THR A 1 466 ? 32.643  10.949  27.385  1   51.991  ? 472  THR A HG21 1 c 
ATOM   7092  H  HG22 . THR A 1 466 ? 31.89   10.265  26.168  1   52.017  ? 472  THR A HG22 1 c 
ATOM   7093  H  HG23 . THR A 1 466 ? 33.416  10.677  26.026  1   51.991  ? 472  THR A HG23 1 c 
ATOM   7094  N  N    . ARG A 1 467 ? 34.681  6.559   27.548  1   76.188  ? 473  ARG A N    1 ? 
ATOM   7095  C  CA   . ARG A 1 467 ? 35.081  5.34    28.229  1   82.861  ? 473  ARG A CA   1 ? 
ATOM   7096  C  C    . ARG A 1 467 ? 33.912  4.783   29.049  1   70.671  ? 473  ARG A C    1 ? 
ATOM   7097  O  O    . ARG A 1 467 ? 33.796  3.575   29.214  1   68.115  ? 473  ARG A O    1 ? 
ATOM   7098  C  CB   . ARG A 1 467 ? 36.344  5.636   29.05   1   91.799  ? 473  ARG A CB   1 ? 
ATOM   7099  C  CG   . ARG A 1 467 ? 37.142  4.403   29.453  1   108.587 ? 473  ARG A CG   1 ? 
ATOM   7100  C  CD   . ARG A 1 467 ? 38.461  4.757   30.146  1   116.116 ? 473  ARG A CD   1 ? 
ATOM   7101  N  NE   . ARG A 1 467 ? 39.319  3.584   30.365  1   117.504 ? 473  ARG A NE   1 ? 
ATOM   7102  C  CZ   . ARG A 1 467 ? 40.634  3.619   30.583  1   106.535 ? 473  ARG A CZ   1 ? 
ATOM   7103  N  NH1  . ARG A 1 467 ? 41.244  4.776   30.75   1   89.66   ? 473  ARG A NH1  1 ? 
ATOM   7104  N  NH2  . ARG A 1 467 ? 41.34   2.499   30.631  1   106.525 ? 473  ARG A NH2  1 ? 
ATOM   7105  H  H    . ARG A 1 467 ? 35.095  7.341   27.777  1   73.767  ? 473  ARG A H    1 c 
ATOM   7106  H  HA   . ARG A 1 467 ? 35.319  4.669   27.539  1   80.394  ? 473  ARG A HA   1 c 
ATOM   7107  H  HB2  . ARG A 1 467 ? 36.926  6.228   28.528  1   92.948  ? 473  ARG A HB2  1 c 
ATOM   7108  H  HB3  . ARG A 1 467 ? 36.082  6.119   29.863  1   93.16   ? 473  ARG A HB3  1 c 
ATOM   7109  H  HG2  . ARG A 1 467 ? 36.601  3.852   30.06   1   106.106 ? 473  ARG A HG2  1 c 
ATOM   7110  H  HG3  . ARG A 1 467 ? 37.336  3.868   28.652  1   106.106 ? 473  ARG A HG3  1 c 
ATOM   7111  H  HD2  . ARG A 1 467 ? 38.943  5.408   29.596  1   114.556 ? 473  ARG A HD2  1 c 
ATOM   7112  H  HD3  . ARG A 1 467 ? 38.267  5.178   31.008  1   114.677 ? 473  ARG A HD3  1 c 
ATOM   7113  H  HE   . ARG A 1 467 ? 38.938  2.801   30.354  1   114.33  ? 473  ARG A HE   1 c 
ATOM   7114  H  HH11 . ARG A 1 467 ? 40.896  5.386   31.29   1   94.672  ? 473  ARG A HH11 1 c 
ATOM   7115  H  HH12 . ARG A 1 467 ? 42.004  4.936   30.322  1   94.581  ? 473  ARG A HH12 1 c 
ATOM   7116  H  HH21 . ARG A 1 467 ? 40.958  1.726   30.433  1   106.637 ? 473  ARG A HH21 1 c 
ATOM   7117  H  HH22 . ARG A 1 467 ? 42.193  2.528   30.863  1   106.421 ? 473  ARG A HH22 1 c 
ATOM   7118  N  N    . GLN A 1 468 ? 33.041  5.662   29.557  1   70.061  ? 474  GLN A N    1 ? 
ATOM   7119  C  CA   . GLN A 1 468 ? 31.904  5.234   30.36   1   65.304  ? 474  GLN A CA   1 ? 
ATOM   7120  C  C    . GLN A 1 468 ? 30.798  4.605   29.519  1   61.586  ? 474  GLN A C    1 ? 
ATOM   7121  O  O    . GLN A 1 468 ? 30.081  3.745   30.024  1   58.876  ? 474  GLN A O    1 ? 
ATOM   7122  C  CB   . GLN A 1 468 ? 31.253  6.393   31.104  1   63.078  ? 474  GLN A CB   1 ? 
ATOM   7123  C  CG   . GLN A 1 468 ? 32.156  7.018   32.155  1   61.608  ? 474  GLN A CG   1 ? 
ATOM   7124  C  CD   . GLN A 1 468 ? 31.468  8.124   32.918  1   65.159  ? 474  GLN A CD   1 ? 
ATOM   7125  O  OE1  . GLN A 1 468 ? 31.014  9.114   32.341  1   66.57   ? 474  GLN A OE1  1 ? 
ATOM   7126  N  NE2  . GLN A 1 468 ? 31.397  7.969   34.231  1   72.64   ? 474  GLN A NE2  1 ? 
ATOM   7127  H  H    . GLN A 1 468 ? 33.163  6.556   29.409  1   69.157  ? 474  GLN A H    1 c 
ATOM   7128  H  HA   . GLN A 1 468 ? 32.221  4.569   31.021  1   65.069  ? 474  GLN A HA   1 c 
ATOM   7129  H  HB2  . GLN A 1 468 ? 30.998  7.081   30.454  1   63.148  ? 474  GLN A HB2  1 c 
ATOM   7130  H  HB3  . GLN A 1 468 ? 30.434  6.073   31.537  1   63.21   ? 474  GLN A HB3  1 c 
ATOM   7131  H  HG2  . GLN A 1 468 ? 32.447  6.325   32.785  1   62.851  ? 474  GLN A HG2  1 c 
ATOM   7132  H  HG3  . GLN A 1 468 ? 32.956  7.382   31.72   1   62.763  ? 474  GLN A HG3  1 c 
ATOM   7133  H  HE21 . GLN A 1 468 ? 30.797  8.432   34.697  1   70.205  ? 474  GLN A HE21 1 c 
ATOM   7134  H  HE22 . GLN A 1 468 ? 31.949  7.41    34.645  1   70.176  ? 474  GLN A HE22 1 c 
ATOM   7135  N  N    . THR A 1 469 ? 30.652  5.025   28.25   1   62.919  ? 475  THR A N    1 ? 
ATOM   7136  C  CA   . THR A 1 469 ? 29.464  4.69    27.471  1   58.381  ? 475  THR A CA   1 ? 
ATOM   7137  C  C    . THR A 1 469 ? 29.16   3.193   27.546  1   60.891  ? 475  THR A C    1 ? 
ATOM   7138  O  O    . THR A 1 469 ? 28.004  2.818   27.751  1   54.011  ? 475  THR A O    1 ? 
ATOM   7139  C  CB   . THR A 1 469 ? 29.598  5.09    26      1   56.348  ? 475  THR A CB   1 ? 
ATOM   7140  O  OG1  . THR A 1 469 ? 29.923  6.478   25.958  1   48.77   ? 475  THR A OG1  1 ? 
ATOM   7141  C  CG2  . THR A 1 469 ? 28.328  4.756   25.223  1   49.124  ? 475  THR A CG2  1 ? 
ATOM   7142  H  H    . THR A 1 469 ? 31.306  5.533   27.863  1   61.605  ? 475  THR A H    1 c 
ATOM   7143  H  HA   . THR A 1 469 ? 28.704  5.18    27.853  1   59.278  ? 475  THR A HA   1 c 
ATOM   7144  H  HB   . THR A 1 469 ? 30.342  4.578   25.601  1   53.761  ? 475  THR A HB   1 c 
ATOM   7145  H  HG1  . THR A 1 469 ? 29.289  6.925   26.354  0   49.38   ? 475  THR A HG1  1 c 
ATOM   7146  H  HG21 . THR A 1 469 ? 28.37   5.166   24.342  1   51.162  ? 475  THR A HG21 1 c 
ATOM   7147  H  HG22 . THR A 1 469 ? 27.554  5.098   25.702  1   51.161  ? 475  THR A HG22 1 c 
ATOM   7148  H  HG23 . THR A 1 469 ? 28.248  3.792   25.125  1   51.198  ? 475  THR A HG23 1 c 
ATOM   7149  N  N    . PHE A 1 470 ? 30.189  2.362   27.305  1   58.094  ? 476  PHE A N    1 ? 
ATOM   7150  C  CA   . PHE A 1 470 ? 30.041  0.92    27.184  1   60.676  ? 476  PHE A CA   1 ? 
ATOM   7151  C  C    . PHE A 1 470 ? 30.575  0.234   28.447  1   61.736  ? 476  PHE A C    1 ? 
ATOM   7152  O  O    . PHE A 1 470 ? 30.84   -0.965  28.448  1   55.443  ? 476  PHE A O    1 ? 
ATOM   7153  C  CB   . PHE A 1 470 ? 30.748  0.501   25.887  1   61.134  ? 476  PHE A CB   1 ? 
ATOM   7154  C  CG   . PHE A 1 470 ? 30.11   1.071   24.623  1   59.233  ? 476  PHE A CG   1 ? 
ATOM   7155  C  CD1  . PHE A 1 470 ? 28.929  0.539   24.118  1   54.05   ? 476  PHE A CD1  1 ? 
ATOM   7156  C  CD2  . PHE A 1 470 ? 30.678  2.144   23.954  1   63.925  ? 476  PHE A CD2  1 ? 
ATOM   7157  C  CE1  . PHE A 1 470 ? 28.318  1.072   22.99   1   50.529  ? 476  PHE A CE1  1 ? 
ATOM   7158  C  CE2  . PHE A 1 470 ? 30.069  2.665   22.814  1   63.719  ? 476  PHE A CE2  1 ? 
ATOM   7159  C  CZ   . PHE A 1 470 ? 28.895  2.117   22.333  1   54.471  ? 476  PHE A CZ   1 ? 
ATOM   7160  H  H    . PHE A 1 470 ? 31.025  2.719   27.208  1   59.357  ? 476  PHE A H    1 c 
ATOM   7161  H  HA   . PHE A 1 470 ? 29.074  0.707   27.095  1   60.399  ? 476  PHE A HA   1 c 
ATOM   7162  H  HB2  . PHE A 1 470 ? 31.684  0.797   25.932  1   60.605  ? 476  PHE A HB2  1 c 
ATOM   7163  H  HB3  . PHE A 1 470 ? 30.743  -0.48   25.831  1   60.568  ? 476  PHE A HB3  1 c 
ATOM   7164  H  HD1  . PHE A 1 470 ? 28.52   -0.183  24.568  1   54.477  ? 476  PHE A HD1  1 c 
ATOM   7165  H  HD2  . PHE A 1 470 ? 31.479  2.526   24.276  1   62.554  ? 476  PHE A HD2  1 c 
ATOM   7166  H  HE1  . PHE A 1 470 ? 27.52   0.689   22.661  1   52.436  ? 476  PHE A HE1  1 c 
ATOM   7167  H  HE2  . PHE A 1 470 ? 30.467  3.392   22.362  1   61.313  ? 476  PHE A HE2  1 c 
ATOM   7168  H  HZ   . PHE A 1 470 ? 28.489  2.471   21.559  1   55.572  ? 476  PHE A HZ   1 c 
ATOM   7169  N  N    . SER A 1 471 ? 30.743  1.017   29.513  1   63.211  ? 477  SER A N    1 ? 
ATOM   7170  C  CA   . SER A 1 471 ? 31.174  0.535   30.812  1   63.519  ? 477  SER A CA   1 ? 
ATOM   7171  C  C    . SER A 1 471 ? 29.95   0.308   31.697  1   66.9    ? 477  SER A C    1 ? 
ATOM   7172  O  O    . SER A 1 471 ? 28.814  0.498   31.278  1   66.487  ? 477  SER A O    1 ? 
ATOM   7173  C  CB   . SER A 1 471 ? 32.087  1.54    31.472  1   63.672  ? 477  SER A CB   1 ? 
ATOM   7174  O  OG   . SER A 1 471 ? 31.34   2.516   32.193  1   54.897  ? 477  SER A OG   1 ? 
ATOM   7175  H  H    . SER A 1 471 ? 30.575  1.91    29.428  1   62.853  ? 477  SER A H    1 c 
ATOM   7176  H  HA   . SER A 1 471 ? 31.658  -0.323  30.7    1   64.022  ? 477  SER A HA   1 c 
ATOM   7177  H  HB2  . SER A 1 471 ? 32.69   1.077   32.084  1   61.462  ? 477  SER A HB2  1 c 
ATOM   7178  H  HB3  . SER A 1 471 ? 32.626  1.982   30.791  1   61.478  ? 477  SER A HB3  1 c 
ATOM   7179  H  HG   . SER A 1 471 ? 31.882  3.072   32.519  0   54.35   ? 477  SER A HG   1 c 
ATOM   7180  N  N    . SER A 1 472 ? 30.202  -0.058  32.951  1   66.873  ? 478  SER A N    1 ? 
ATOM   7181  C  CA   . SER A 1 472 ? 29.136  -0.245  33.917  1   62.047  ? 478  SER A CA   1 ? 
ATOM   7182  C  C    . SER A 1 472 ? 28.911  1.057   34.665  1   52.319  ? 478  SER A C    1 ? 
ATOM   7183  O  O    . SER A 1 472 ? 28.073  1.089   35.54   1   53.006  ? 478  SER A O    1 ? 
ATOM   7184  C  CB   . SER A 1 472 ? 29.437  -1.368  34.879  1   61.248  ? 478  SER A CB   1 ? 
ATOM   7185  O  OG   . SER A 1 472 ? 30.369  -0.922  35.855  1   54.538  ? 478  SER A OG   1 ? 
ATOM   7186  H  H    . SER A 1 472 ? 31.065  -0.207  33.214  1   65.694  ? 478  SER A H    1 c 
ATOM   7187  H  HA   . SER A 1 472 ? 28.305  -0.47   33.427  1   60.929  ? 478  SER A HA   1 c 
ATOM   7188  H  HB2  . SER A 1 472 ? 28.612  -1.653  35.317  1   59.752  ? 478  SER A HB2  1 c 
ATOM   7189  H  HB3  . SER A 1 472 ? 29.809  -2.126  34.39   1   59.752  ? 478  SER A HB3  1 c 
ATOM   7190  H  HG   . SER A 1 472 ? 30.514  -1.571  36.392  0   55.18   ? 478  SER A HG   1 c 
ATOM   7191  N  N    . GLU A 1 473 ? 29.634  2.128   34.309  1   54.627  ? 479  GLU A N    1 ? 
ATOM   7192  C  CA   . GLU A 1 473 ? 29.208  3.474   34.682  1   62.499  ? 479  GLU A CA   1 ? 
ATOM   7193  C  C    . GLU A 1 473 ? 28.273  4.105   33.63   1   53.099  ? 479  GLU A C    1 ? 
ATOM   7194  O  O    . GLU A 1 473 ? 28.019  5.305   33.68   1   48.938  ? 479  GLU A O    1 ? 
ATOM   7195  C  CB   . GLU A 1 473 ? 30.399  4.412   34.894  1   66.394  ? 479  GLU A CB   1 ? 
ATOM   7196  C  CG   . GLU A 1 473 ? 31.146  4.218   36.213  1   70.691  ? 479  GLU A CG   1 ? 
ATOM   7197  C  CD   . GLU A 1 473 ? 31.692  5.551   36.709  1   83.256  ? 479  GLU A CD   1 ? 
ATOM   7198  O  OE1  . GLU A 1 473 ? 30.869  6.423   37.092  1   83.998  ? 479  GLU A OE1  1 ? 
ATOM   7199  O  OE2  . GLU A 1 473 ? 32.925  5.748   36.67   1   71.912  ? 479  GLU A OE2  1 ? 
ATOM   7200  H  H    . GLU A 1 473 ? 30.413  2.023   33.844  1   55.941  ? 479  GLU A H    1 c 
ATOM   7201  H  HA   . GLU A 1 473 ? 28.712  3.416   35.538  1   59.754  ? 479  GLU A HA   1 c 
ATOM   7202  H  HB2  . GLU A 1 473 ? 31.034  4.281   34.16   1   66.274  ? 479  GLU A HB2  1 c 
ATOM   7203  H  HB3  . GLU A 1 473 ? 30.084  5.338   34.851  1   66.311  ? 479  GLU A HB3  1 c 
ATOM   7204  H  HG2  . GLU A 1 473 ? 30.537  3.848   36.887  1   72.252  ? 479  GLU A HG2  1 c 
ATOM   7205  H  HG3  . GLU A 1 473 ? 31.89   3.592   36.083  1   72.326  ? 479  GLU A HG3  1 c 
ATOM   7206  N  N    . ARG A 1 474 ? 27.752  3.315   32.681  1   55.004  ? 480  ARG A N    1 ? 
ATOM   7207  C  CA   . ARG A 1 474 ? 26.969  3.843   31.563  1   55.3    ? 480  ARG A CA   1 ? 
ATOM   7208  C  C    . ARG A 1 474 ? 25.802  4.705   32.043  1   51.464  ? 480  ARG A C    1 ? 
ATOM   7209  O  O    . ARG A 1 474 ? 25.548  5.726   31.424  1   49.134  ? 480  ARG A O    1 ? 
ATOM   7210  C  CB   . ARG A 1 474 ? 26.445  2.708   30.679  1   52.428  ? 480  ARG A CB   1 ? 
ATOM   7211  C  CG   . ARG A 1 474 ? 25.447  3.09    29.602  1   50.871  ? 480  ARG A CG   1 ? 
ATOM   7212  C  CD   . ARG A 1 474 ? 25.153  1.867   28.765  1   50.788  ? 480  ARG A CD   1 ? 
ATOM   7213  N  NE   . ARG A 1 474 ? 24.162  2.125   27.715  1   51.954  ? 480  ARG A NE   1 ? 
ATOM   7214  C  CZ   . ARG A 1 474 ? 24.398  2.347   26.415  1   51.949  ? 480  ARG A CZ   1 ? 
ATOM   7215  N  NH1  . ARG A 1 474 ? 25.617  2.567   25.951  1   51.163  ? 480  ARG A NH1  1 ? 
ATOM   7216  N  NH2  . ARG A 1 474 ? 23.382  2.388   25.576  1   47.302  ? 480  ARG A NH2  1 ? 
ATOM   7217  H  H    . ARG A 1 474 ? 27.883  2.412   32.729  1   54.612  ? 480  ARG A H    1 c 
ATOM   7218  H  HA   . ARG A 1 474 ? 27.568  4.41    31.013  1   53.96   ? 480  ARG A HA   1 c 
ATOM   7219  H  HB2  . ARG A 1 474 ? 27.215  2.28    30.247  1   52.756  ? 480  ARG A HB2  1 c 
ATOM   7220  H  HB3  . ARG A 1 474 ? 26.028  2.037   31.261  1   52.724  ? 480  ARG A HB3  1 c 
ATOM   7221  H  HG2  . ARG A 1 474 ? 24.616  3.413   30.012  1   51.203  ? 480  ARG A HG2  1 c 
ATOM   7222  H  HG3  . ARG A 1 474 ? 25.823  3.796   29.032  1   51.214  ? 480  ARG A HG3  1 c 
ATOM   7223  H  HD2  . ARG A 1 474 ? 25.981  1.546   28.355  1   51.102  ? 480  ARG A HD2  1 c 
ATOM   7224  H  HD3  . ARG A 1 474 ? 24.819  1.158   29.351  1   51.036  ? 480  ARG A HD3  1 c 
ATOM   7225  H  HE   . ARG A 1 474 ? 23.327  2.136   27.962  1   51.619  ? 480  ARG A HE   1 c 
ATOM   7226  H  HH11 . ARG A 1 474 ? 26.179  3.072   26.411  1   51.395  ? 480  ARG A HH11 1 c 
ATOM   7227  H  HH12 . ARG A 1 474 ? 25.864  2.21    25.181  1   51.381  ? 480  ARG A HH12 1 c 
ATOM   7228  H  HH21 . ARG A 1 474 ? 22.571  2.595   25.871  1   48.684  ? 480  ARG A HH21 1 c 
ATOM   7229  H  HH22 . ARG A 1 474 ? 23.515  2.21    24.717  1   48.723  ? 480  ARG A HH22 1 c 
ATOM   7230  N  N    . TYR A 1 475 ? 25.124  4.317   33.147  1   50.153  ? 481  TYR A N    1 ? 
ATOM   7231  C  CA   . TYR A 1 475 ? 23.865  4.94    33.55   1   44.047  ? 481  TYR A CA   1 ? 
ATOM   7232  C  C    . TYR A 1 475 ? 24.137  6.069   34.522  1   44.655  ? 481  TYR A C    1 ? 
ATOM   7233  O  O    . TYR A 1 475 ? 23.199  6.565   35.144  1   46.203  ? 481  TYR A O    1 ? 
ATOM   7234  C  CB   . TYR A 1 475 ? 22.828  3.928   34.059  1   47.367  ? 481  TYR A CB   1 ? 
ATOM   7235  C  CG   . TYR A 1 475 ? 22.507  2.972   32.924  1   44.001  ? 481  TYR A CG   1 ? 
ATOM   7236  C  CD1  . TYR A 1 475 ? 21.577  3.313   31.958  1   40.466  ? 481  TYR A CD1  1 ? 
ATOM   7237  C  CD2  . TYR A 1 475 ? 23.253  1.814   32.722  1   43.343  ? 481  TYR A CD2  1 ? 
ATOM   7238  C  CE1  . TYR A 1 475 ? 21.339  2.491   30.866  1   41.956  ? 481  TYR A CE1  1 ? 
ATOM   7239  C  CE2  . TYR A 1 475 ? 23.03   0.988   31.627  1   40.919  ? 481  TYR A CE2  1 ? 
ATOM   7240  C  CZ   . TYR A 1 475 ? 22.078  1.334   30.686  1   40.591  ? 481  TYR A CZ   1 ? 
ATOM   7241  O  OH   . TYR A 1 475 ? 21.798  0.534   29.607  1   46.267  ? 481  TYR A OH   1 ? 
ATOM   7242  H  H    . TYR A 1 475 ? 25.455  3.635   33.657  1   49.107  ? 481  TYR A H    1 c 
ATOM   7243  H  HA   . TYR A 1 475 ? 23.476  5.355   32.734  1   45.907  ? 481  TYR A HA   1 c 
ATOM   7244  H  HB2  . TYR A 1 475 ? 23.2    3.431   34.82   1   45.833  ? 481  TYR A HB2  1 c 
ATOM   7245  H  HB3  . TYR A 1 475 ? 22.013  4.403   34.335  1   45.828  ? 481  TYR A HB3  1 c 
ATOM   7246  H  HD1  . TYR A 1 475 ? 21.08   4.11    32.054  1   41.654  ? 481  TYR A HD1  1 c 
ATOM   7247  H  HD2  . TYR A 1 475 ? 23.922  1.581   33.345  1   42.907  ? 481  TYR A HD2  1 c 
ATOM   7248  H  HE1  . TYR A 1 475 ? 20.681  2.728   30.235  1   41.352  ? 481  TYR A HE1  1 c 
ATOM   7249  H  HE2  . TYR A 1 475 ? 23.525  0.194   31.525  1   41.45   ? 481  TYR A HE2  1 c 
ATOM   7250  H  HH   . TYR A 1 475 ? 22.283  0.776   28.919  0   45.29   ? 481  TYR A HH   1 c 
ATOM   7251  N  N    . THR A 1 476 ? 25.402  6.519   34.573  1   48.135  ? 482  THR A N    1 ? 
ATOM   7252  C  CA   . THR A 1 476 ? 25.759  7.817   35.146  1   52.34   ? 482  THR A CA   1 ? 
ATOM   7253  C  C    . THR A 1 476 ? 25.667  8.91    34.076  1   48.844  ? 482  THR A C    1 ? 
ATOM   7254  O  O    . THR A 1 476 ? 25.716  10.101  34.39   1   44.2    ? 482  THR A O    1 ? 
ATOM   7255  C  CB   . THR A 1 476 ? 27.162  7.763   35.78   1   58.611  ? 482  THR A CB   1 ? 
ATOM   7256  O  OG1  . THR A 1 476 ? 28.067  7.151   34.86   1   56.597  ? 482  THR A OG1  1 ? 
ATOM   7257  C  CG2  . THR A 1 476 ? 27.208  6.92    37.046  1   53.921  ? 482  THR A CG2  1 ? 
ATOM   7258  H  H    . THR A 1 476 ? 26.076  5.988   34.261  1   48.265  ? 482  THR A H    1 c 
ATOM   7259  H  HA   . THR A 1 476 ? 25.113  8.025   35.855  1   51.831  ? 482  THR A HA   1 c 
ATOM   7260  H  HB   . THR A 1 476 ? 27.471  8.678   35.985  1   56.135  ? 482  THR A HB   1 c 
ATOM   7261  H  HG1  . THR A 1 476 ? 27.792  6.282   34.734  0   54.68   ? 482  THR A HG1  1 c 
ATOM   7262  H  HG21 . THR A 1 476 ? 28.116  6.903   37.393  1   55.265  ? 482  THR A HG21 1 c 
ATOM   7263  H  HG22 . THR A 1 476 ? 26.922  6.013   36.843  1   55.264  ? 482  THR A HG22 1 c 
ATOM   7264  H  HG23 . THR A 1 476 ? 26.614  7.303   37.713  1   55.265  ? 482  THR A HG23 1 c 
ATOM   7265  N  N    . ILE A 1 477 ? 25.551  8.507   32.806  1   50.9    ? 483  ILE A N    1 ? 
ATOM   7266  C  CA   . ILE A 1 477 ? 25.376  9.448   31.706  1   49.033  ? 483  ILE A CA   1 ? 
ATOM   7267  C  C    . ILE A 1 477 ? 23.903  9.862   31.621  1   40.687  ? 483  ILE A C    1 ? 
ATOM   7268  O  O    . ILE A 1 477 ? 23.029  9.021   31.46   1   45.898  ? 483  ILE A O    1 ? 
ATOM   7269  C  CB   . ILE A 1 477 ? 25.896  8.821   30.398  1   50.802  ? 483  ILE A CB   1 ? 
ATOM   7270  C  CG1  . ILE A 1 477 ? 27.372  8.435   30.516  1   48.066  ? 483  ILE A CG1  1 ? 
ATOM   7271  C  CG2  . ILE A 1 477 ? 25.655  9.755   29.212  1   50.746  ? 483  ILE A CG2  1 ? 
ATOM   7272  C  CD1  . ILE A 1 477 ? 27.835  7.431   29.468  1   52.271  ? 483  ILE A CD1  1 ? 
ATOM   7273  H  H    . ILE A 1 477 ? 25.586  7.615   32.613  1   49.93   ? 483  ILE A H    1 c 
ATOM   7274  H  HA   . ILE A 1 477 ? 25.912  10.243  31.895  1   47.903  ? 483  ILE A HA   1 c 
ATOM   7275  H  HB   . ILE A 1 477 ? 25.389  8.004   30.242  1   49.837  ? 483  ILE A HB   1 c 
ATOM   7276  H  HG12 . ILE A 1 477 ? 27.915  9.245   30.436  1   49.618  ? 483  ILE A HG12 1 c 
ATOM   7277  H  HG13 . ILE A 1 477 ? 27.531  8.055   31.404  1   49.623  ? 483  ILE A HG13 1 c 
ATOM   7278  H  HG21 . ILE A 1 477 ? 26.061  9.379   28.413  1   50.745  ? 483  ILE A HG21 1 c 
ATOM   7279  H  HG22 . ILE A 1 477 ? 26.05   10.624  29.396  1   50.738  ? 483  ILE A HG22 1 c 
ATOM   7280  H  HG23 . ILE A 1 477 ? 24.7    9.86    29.066  1   50.651  ? 483  ILE A HG23 1 c 
ATOM   7281  H  HD11 . ILE A 1 477 ? 27.282  6.628   29.519  1   51.015  ? 483  ILE A HD11 1 c 
ATOM   7282  H  HD12 . ILE A 1 477 ? 28.767  7.193   29.635  1   51.072  ? 483  ILE A HD12 1 c 
ATOM   7283  H  HD13 . ILE A 1 477 ? 27.755  7.823   28.578  1   51.015  ? 483  ILE A HD13 1 c 
ATOM   7284  N  N    . TRP A 1 478 ? 23.626  11.161  31.747  1   38.844  ? 484  TRP A N    1 ? 
ATOM   7285  C  CA   . TRP A 1 478 ? 22.256  11.649  31.889  1   44.796  ? 484  TRP A CA   1 ? 
ATOM   7286  C  C    . TRP A 1 478 ? 21.35   11.232  30.722  1   45.684  ? 484  TRP A C    1 ? 
ATOM   7287  O  O    . TRP A 1 478 ? 20.209  10.899  30.973  1   42.678  ? 484  TRP A O    1 ? 
ATOM   7288  C  CB   . TRP A 1 478 ? 22.231  13.169  32.093  1   48.992  ? 484  TRP A CB   1 ? 
ATOM   7289  C  CG   . TRP A 1 478 ? 22.658  13.992  30.904  1   57.946  ? 484  TRP A CG   1 ? 
ATOM   7290  C  CD1  . TRP A 1 478 ? 23.922  14.419  30.641  1   58.224  ? 484  TRP A CD1  1 ? 
ATOM   7291  C  CD2  . TRP A 1 478 ? 21.832  14.526  29.841  1   58.773  ? 484  TRP A CD2  1 ? 
ATOM   7292  N  NE1  . TRP A 1 478 ? 23.947  15.154  29.488  1   63.059  ? 484  TRP A NE1  1 ? 
ATOM   7293  C  CE2  . TRP A 1 478 ? 22.684  15.24   28.974  1   60.964  ? 484  TRP A CE2  1 ? 
ATOM   7294  C  CE3  . TRP A 1 478 ? 20.471  14.475  29.533  1   54.714  ? 484  TRP A CE3  1 ? 
ATOM   7295  C  CZ2  . TRP A 1 478 ? 22.219  15.896  27.837  1   60.537  ? 484  TRP A CZ2  1 ? 
ATOM   7296  C  CZ3  . TRP A 1 478 ? 20.005  15.138  28.42   1   52.25   ? 484  TRP A CZ3  1 ? 
ATOM   7297  C  CH2  . TRP A 1 478 ? 20.869  15.836  27.579  1   52.443  ? 484  TRP A CH2  1 ? 
ATOM   7298  H  H    . TRP A 1 478 ? 24.31   11.768  31.743  1   40.866  ? 484  TRP A H    1 c 
ATOM   7299  H  HA   . TRP A 1 478 ? 21.884  11.236  32.714  1   44.438  ? 484  TRP A HA   1 c 
ATOM   7300  H  HB2  . TRP A 1 478 ? 21.319  13.431  32.344  1   49.871  ? 484  TRP A HB2  1 c 
ATOM   7301  H  HB3  . TRP A 1 478 ? 22.813  13.388  32.852  1   49.901  ? 484  TRP A HB3  1 c 
ATOM   7302  H  HD1  . TRP A 1 478 ? 24.683  14.221  31.162  1   59.085  ? 484  TRP A HD1  1 c 
ATOM   7303  H  HE1  . TRP A 1 478 ? 24.661  15.514  29.137  1   61.303  ? 484  TRP A HE1  1 c 
ATOM   7304  H  HE3  . TRP A 1 478 ? 19.875  14.011  30.096  1   54.972  ? 484  TRP A HE3  1 c 
ATOM   7305  H  HZ2  . TRP A 1 478 ? 22.805  16.376  27.277  1   58.449  ? 484  TRP A HZ2  1 c 
ATOM   7306  H  HZ3  . TRP A 1 478 ? 19.088  15.098  28.208  1   53.004  ? 484  TRP A HZ3  1 c 
ATOM   7307  H  HH2  . TRP A 1 478 ? 20.525  16.265  26.816  1   54.285  ? 484  TRP A HH2  1 c 
ATOM   7308  N  N    . THR A 1 479 ? 21.845  11.171  29.468  1   40.868  ? 485  THR A N    1 ? 
ATOM   7309  C  CA   . THR A 1 479 ? 21.005  10.802  28.335  1   41.346  ? 485  THR A CA   1 ? 
ATOM   7310  C  C    . THR A 1 479 ? 20.474  9.363   28.458  1   42.727  ? 485  THR A C    1 ? 
ATOM   7311  O  O    . THR A 1 479 ? 19.545  8.991   27.741  1   37.954  ? 485  THR A O    1 ? 
ATOM   7312  C  CB   . THR A 1 479 ? 21.784  10.957  27.027  1   42.954  ? 485  THR A CB   1 ? 
ATOM   7313  O  OG1  . THR A 1 479 ? 22.897  10.072  27.132  1   42.125  ? 485  THR A OG1  1 ? 
ATOM   7314  C  CG2  . THR A 1 479 ? 22.255  12.376  26.794  1   41.176  ? 485  THR A CG2  1 ? 
ATOM   7315  H  H    . THR A 1 479 ? 22.728  11.356  29.324  1   42.056  ? 485  THR A H    1 c 
ATOM   7316  H  HA   . THR A 1 479 ? 20.239  11.415  28.311  1   41.796  ? 485  THR A HA   1 c 
ATOM   7317  H  HB   . THR A 1 479 ? 21.216  10.677  26.27   1   42.166  ? 485  THR A HB   1 c 
ATOM   7318  H  HG1  . THR A 1 479 ? 23.372  10.299  27.802  0   42.13   ? 485  THR A HG1  1 c 
ATOM   7319  H  HG21 . THR A 1 479 ? 22.675  12.439  25.919  1   41.695  ? 485  THR A HG21 1 c 
ATOM   7320  H  HG22 . THR A 1 479 ? 22.899  12.623  27.478  1   41.693  ? 485  THR A HG22 1 c 
ATOM   7321  H  HG23 . THR A 1 479 ? 21.495  12.981  26.832  1   41.695  ? 485  THR A HG23 1 c 
ATOM   7322  N  N    . MET A 1 480 ? 21.095  8.541   29.318  1   36.681  ? 486  MET A N    1 ? 
ATOM   7323  C  CA   . MET A 1 480 ? 20.783  7.123   29.384  1   39.376  ? 486  MET A CA   1 ? 
ATOM   7324  C  C    . MET A 1 480 ? 19.77   6.84    30.495  1   37.166  ? 486  MET A C    1 ? 
ATOM   7325  O  O    . MET A 1 480 ? 19.264  5.722   30.604  1   40.789  ? 486  MET A O    1 ? 
ATOM   7326  C  CB   . MET A 1 480 ? 22.056  6.33    29.687  1   42.389  ? 486  MET A CB   1 ? 
ATOM   7327  C  CG   . MET A 1 480 ? 23.257  6.755   28.875  1   41.915  ? 486  MET A CG   1 ? 
ATOM   7328  S  SD   . MET A 1 480 ? 23.253  5.891   27.303  1   44.971  ? 486  MET A SD   1 ? 
ATOM   7329  C  CE   . MET A 1 480 ? 24.807  6.547   26.669  1   48.914  ? 486  MET A CE   1 ? 
ATOM   7330  H  H    . MET A 1 480 ? 21.736  8.873   29.878  1   38.805  ? 486  MET A H    1 c 
ATOM   7331  H  HA   . MET A 1 480 ? 20.406  6.833   28.514  1   38.96   ? 486  MET A HA   1 c 
ATOM   7332  H  HB2  . MET A 1 480 ? 22.267  6.431   30.64   1   41.555  ? 486  MET A HB2  1 c 
ATOM   7333  H  HB3  . MET A 1 480 ? 21.879  5.379   29.521  1   41.59   ? 486  MET A HB3  1 c 
ATOM   7334  H  HG2  . MET A 1 480 ? 23.239  7.717   28.717  1   42.538  ? 486  MET A HG2  1 c 
ATOM   7335  H  HG3  . MET A 1 480 ? 24.077  6.536   29.359  1   42.668  ? 486  MET A HG3  1 c 
ATOM   7336  H  HE1  . MET A 1 480 ? 24.98   6.175   25.784  1   47.902  ? 486  MET A HE1  1 c 
ATOM   7337  H  HE2  . MET A 1 480 ? 24.749  7.518   26.608  1   47.902  ? 486  MET A HE2  1 c 
ATOM   7338  H  HE3  . MET A 1 480 ? 25.533  6.302   27.271  1   47.902  ? 486  MET A HE3  1 c 
ATOM   7339  N  N    . GLN A 1 481 ? 19.517  7.856   31.329  1   39.331  ? 487  GLN A N    1 ? 
ATOM   7340  C  CA   . GLN A 1 481 ? 18.768  7.708   32.572  1   41.835  ? 487  GLN A CA   1 ? 
ATOM   7341  C  C    . GLN A 1 481 ? 17.298  8.094   32.393  1   43.194  ? 487  GLN A C    1 ? 
ATOM   7342  O  O    . GLN A 1 481 ? 16.975  9.124   31.797  1   40.199  ? 487  GLN A O    1 ? 
ATOM   7343  C  CB   . GLN A 1 481 ? 19.306  8.695   33.608  1   45.248  ? 487  GLN A CB   1 ? 
ATOM   7344  C  CG   . GLN A 1 481 ? 20.65   8.317   34.207  1   43.82   ? 487  GLN A CG   1 ? 
ATOM   7345  C  CD   . GLN A 1 481 ? 21.26   9.42    35.04   1   47.945  ? 487  GLN A CD   1 ? 
ATOM   7346  O  OE1  . GLN A 1 481 ? 20.772  10.559  35.124  1   40.638  ? 487  GLN A OE1  1 ? 
ATOM   7347  N  NE2  . GLN A 1 481 ? 22.374  9.066   35.665  1   52.076  ? 487  GLN A NE2  1 ? 
ATOM   7348  H  H    . GLN A 1 481 ? 19.819  8.689   31.11   1   39.41   ? 487  GLN A H    1 c 
ATOM   7349  H  HA   . GLN A 1 481 ? 18.843  6.774   32.896  1   42.085  ? 487  GLN A HA   1 c 
ATOM   7350  H  HB2  . GLN A 1 481 ? 19.384  9.575   33.186  1   44.07   ? 487  GLN A HB2  1 c 
ATOM   7351  H  HB3  . GLN A 1 481 ? 18.652  8.772   34.331  1   44.062  ? 487  GLN A HB3  1 c 
ATOM   7352  H  HG2  . GLN A 1 481 ? 20.54   7.521   34.769  1   45.097  ? 487  GLN A HG2  1 c 
ATOM   7353  H  HG3  . GLN A 1 481 ? 21.272  8.087   33.484  1   45.07   ? 487  GLN A HG3  1 c 
ATOM   7354  H  HE21 . GLN A 1 481 ? 22.898  9.69    36.016  1   50.651  ? 487  GLN A HE21 1 c 
ATOM   7355  H  HE22 . GLN A 1 481 ? 22.594  8.209   35.735  1   50.611  ? 487  GLN A HE22 1 c 
ATOM   7356  N  N    . SER A 1 482 ? 16.418  7.327   33.034  1   38.18   ? 488  SER A N    1 ? 
ATOM   7357  C  CA   . SER A 1 482 ? 14.992  7.569   32.948  1   38.521  ? 488  SER A CA   1 ? 
ATOM   7358  C  C    . SER A 1 482 ? 14.675  8.955   33.512  1   35.696  ? 488  SER A C    1 ? 
ATOM   7359  O  O    . SER A 1 482 ? 13.648  9.544   33.198  1   41.747  ? 488  SER A O    1 ? 
ATOM   7360  C  CB   . SER A 1 482 ? 14.203  6.446   33.618  1   37.43   ? 488  SER A CB   1 ? 
ATOM   7361  O  OG   . SER A 1 482 ? 14.178  6.55    35.033  1   36.717  ? 488  SER A OG   1 ? 
ATOM   7362  H  H    . SER A 1 482 ? 16.717  6.63    33.545  1   39.409  ? 488  SER A H    1 c 
ATOM   7363  H  HA   . SER A 1 482 ? 14.75   7.578   31.988  1   37.756  ? 488  SER A HA   1 c 
ATOM   7364  H  HB2  . SER A 1 482 ? 13.286  6.458   33.281  1   37.51   ? 488  SER A HB2  1 c 
ATOM   7365  H  HB3  . SER A 1 482 ? 14.597  5.589   33.37   1   37.553  ? 488  SER A HB3  1 c 
ATOM   7366  H  HG   . SER A 1 482 ? 13.755  5.91    35.366  0   35.83   ? 488  SER A HG   1 c 
ATOM   7367  N  N    . ASN A 1 483 ? 15.594  9.488   34.311  1   39.231  ? 489  ASN A N    1 ? 
ATOM   7368  C  CA   . ASN A 1 483 ? 15.501  10.821  34.892  1   38.278  ? 489  ASN A CA   1 ? 
ATOM   7369  C  C    . ASN A 1 483 ? 15.283  11.872  33.806  1   38.034  ? 489  ASN A C    1 ? 
ATOM   7370  O  O    . ASN A 1 483 ? 14.613  12.881  34.051  1   28.056  ? 489  ASN A O    1 ? 
ATOM   7371  C  CB   . ASN A 1 483 ? 16.787  11.2    35.632  1   42.727  ? 489  ASN A CB   1 ? 
ATOM   7372  C  CG   . ASN A 1 483 ? 17.21   10.225  36.721  1   46.215  ? 489  ASN A CG   1 ? 
ATOM   7373  O  OD1  . ASN A 1 483 ? 17.474  9.038   36.463  1   43.224  ? 489  ASN A OD1  1 ? 
ATOM   7374  N  ND2  . ASN A 1 483 ? 17.309  10.724  37.947  1   42.047  ? 489  ASN A ND2  1 ? 
ATOM   7375  H  H    . ASN A 1 483 ? 16.318  8.978   34.536  1   38.294  ? 489  ASN A H    1 c 
ATOM   7376  H  HA   . ASN A 1 483 ? 14.754  10.843  35.533  1   39.201  ? 489  ASN A HA   1 c 
ATOM   7377  H  HB2  . ASN A 1 483 ? 17.513  11.269  34.98   1   42.404  ? 489  ASN A HB2  1 c 
ATOM   7378  H  HB3  . ASN A 1 483 ? 16.667  12.085  36.031  1   42.419  ? 489  ASN A HB3  1 c 
ATOM   7379  H  HD21 . ASN A 1 483 ? 17.556  10.197  38.616  1   43.285  ? 489  ASN A HD21 1 c 
ATOM   7380  H  HD22 . ASN A 1 483 ? 17.13   11.579  38.101  1   43.276  ? 489  ASN A HD22 1 c 
ATOM   7381  N  N    . TYR A 1 484 ? 15.928  11.665  32.634  1   35.83   ? 490  TYR A N    1 ? 
ATOM   7382  C  CA   . TYR A 1 484 ? 15.932  12.634  31.549  1   35.843  ? 490  TYR A CA   1 ? 
ATOM   7383  C  C    . TYR A 1 484 ? 15.062  12.137  30.385  1   39.309  ? 490  TYR A C    1 ? 
ATOM   7384  O  O    . TYR A 1 484 ? 15.258  12.488  29.225  1   43.429  ? 490  TYR A O    1 ? 
ATOM   7385  C  CB   . TYR A 1 484 ? 17.41   12.939  31.25   1   37.952  ? 490  TYR A CB   1 ? 
ATOM   7386  C  CG   . TYR A 1 484 ? 17.984  13.873  32.308  1   38.143  ? 490  TYR A CG   1 ? 
ATOM   7387  C  CD1  . TYR A 1 484 ? 17.655  15.226  32.31   1   40.786  ? 490  TYR A CD1  1 ? 
ATOM   7388  C  CD2  . TYR A 1 484 ? 18.738  13.379  33.376  1   42.626  ? 490  TYR A CD2  1 ? 
ATOM   7389  C  CE1  . TYR A 1 484 ? 18.104  16.072  33.31   1   44.507  ? 490  TYR A CE1  1 ? 
ATOM   7390  C  CE2  . TYR A 1 484 ? 19.217  14.214  34.375  1   37.454  ? 490  TYR A CE2  1 ? 
ATOM   7391  C  CZ   . TYR A 1 484 ? 18.874  15.552  34.344  1   46.12   ? 490  TYR A CZ   1 ? 
ATOM   7392  O  OH   . TYR A 1 484 ? 19.315  16.371  35.319  1   48.017  ? 490  TYR A OH   1 ? 
ATOM   7393  H  H    . TYR A 1 484 ? 16.392  10.886  32.518  1   36.415  ? 490  TYR A H    1 c 
ATOM   7394  H  HA   . TYR A 1 484 ? 15.518  13.471  31.89   1   36.805  ? 490  TYR A HA   1 c 
ATOM   7395  H  HB2  . TYR A 1 484 ? 17.918  12.099  31.243  1   37.524  ? 490  TYR A HB2  1 c 
ATOM   7396  H  HB3  . TYR A 1 484 ? 17.479  13.365  30.366  1   37.541  ? 490  TYR A HB3  1 c 
ATOM   7397  H  HD1  . TYR A 1 484 ? 17.116  15.574  31.618  1   41.016  ? 490  TYR A HD1  1 c 
ATOM   7398  H  HD2  . TYR A 1 484 ? 18.956  12.461  33.401  1   40.361  ? 490  TYR A HD2  1 c 
ATOM   7399  H  HE1  . TYR A 1 484 ? 17.889  16.988  33.292  1   43.889  ? 490  TYR A HE1  1 c 
ATOM   7400  H  HE2  . TYR A 1 484 ? 19.734  13.87   35.083  1   40.554  ? 490  TYR A HE2  1 c 
ATOM   7401  H  HH   . TYR A 1 484 ? 18.764  16.396  35.981  0   47.19   ? 490  TYR A HH   1 c 
ATOM   7402  N  N    . HIS A 1 485 ? 14.118  11.257  30.692  1   36.93   ? 491  HIS A N    1 ? 
ATOM   7403  C  CA   . HIS A 1 485 ? 13.102  10.856  29.74   1   34.496  ? 491  HIS A CA   1 ? 
ATOM   7404  C  C    . HIS A 1 485 ? 11.78   11.317  30.319  1   37.231  ? 491  HIS A C    1 ? 
ATOM   7405  O  O    . HIS A 1 485 ? 11.754  11.873  31.436  1   34.162  ? 491  HIS A O    1 ? 
ATOM   7406  C  CB   . HIS A 1 485 ? 13.109  9.339   29.489  1   32.999  ? 491  HIS A CB   1 ? 
ATOM   7407  C  CG   . HIS A 1 485 ? 14.325  8.911   28.762  1   37.111  ? 491  HIS A CG   1 ? 
ATOM   7408  N  ND1  . HIS A 1 485 ? 15.532  8.773   29.4    1   36.149  ? 491  HIS A ND1  1 ? 
ATOM   7409  C  CD2  . HIS A 1 485 ? 14.551  8.667   27.462  1   38.087  ? 491  HIS A CD2  1 ? 
ATOM   7410  C  CE1  . HIS A 1 485 ? 16.438  8.401   28.497  1   43.436  ? 491  HIS A CE1  1 ? 
ATOM   7411  N  NE2  . HIS A 1 485 ? 15.872  8.341   27.314  1   32.507  ? 491  HIS A NE2  1 ? 
ATOM   7412  H  H    . HIS A 1 485 ? 14.1    10.888  31.527  1   36.891  ? 491  HIS A H    1 c 
ATOM   7413  H  HA   . HIS A 1 485 ? 13.252  11.331  28.89   1   35.285  ? 491  HIS A HA   1 c 
ATOM   7414  H  HB2  . HIS A 1 485 ? 13.068  8.873   30.352  1   34.258  ? 491  HIS A HB2  1 c 
ATOM   7415  H  HB3  . HIS A 1 485 ? 12.319  9.094   28.963  1   34.257  ? 491  HIS A HB3  1 c 
ATOM   7416  H  HD1  . HIS A 1 485 ? 15.687  8.918   30.242  0   36.23   ? 491  HIS A HD1  1 c 
ATOM   7417  H  HD2  . HIS A 1 485 ? 13.917  8.692   26.772  1   36.534  ? 491  HIS A HD2  1 c 
ATOM   7418  H  HE1  . HIS A 1 485 ? 17.344  8.228   28.683  1   38.851  ? 491  HIS A HE1  1 c 
ATOM   7419  H  HE2  . HIS A 1 485 ? 16.264  8.093   26.557  0   32.14   ? 491  HIS A HE2  1 c 
ATOM   7420  N  N    . ASN A 1 486 ? 10.708  11.024  29.576  1   33.997  ? 492  ASN A N    1 ? 
ATOM   7421  C  CA   . ASN A 1 486 ? 9.41    11.616  29.872  1   40.189  ? 492  ASN A CA   1 ? 
ATOM   7422  C  C    . ASN A 1 486 ? 8.612   10.646  30.734  1   37.527  ? 492  ASN A C    1 ? 
ATOM   7423  O  O    . ASN A 1 486 ? 7.675   10.025  30.251  1   30.947  ? 492  ASN A O    1 ? 
ATOM   7424  C  CB   . ASN A 1 486 ? 8.689   12.015  28.593  1   43.383  ? 492  ASN A CB   1 ? 
ATOM   7425  C  CG   . ASN A 1 486 ? 9.447   13.09   27.851  1   40.933  ? 492  ASN A CG   1 ? 
ATOM   7426  O  OD1  . ASN A 1 486 ? 9.903   14.059  28.478  1   47.144  ? 492  ASN A OD1  1 ? 
ATOM   7427  N  ND2  . ASN A 1 486 ? 9.582   12.918  26.543  1   43.355  ? 492  ASN A ND2  1 ? 
ATOM   7428  H  H    . ASN A 1 486 ? 10.784  10.46   28.862  1   36.026  ? 492  ASN A H    1 c 
ATOM   7429  H  HA   . ASN A 1 486 ? 9.558   12.437  30.391  1   38.967  ? 492  ASN A HA   1 c 
ATOM   7430  H  HB2  . ASN A 1 486 ? 8.589   11.23   28.018  1   41.959  ? 492  ASN A HB2  1 c 
ATOM   7431  H  HB3  . ASN A 1 486 ? 7.797   12.346  28.816  1   41.993  ? 492  ASN A HB3  1 c 
ATOM   7432  H  HD21 . ASN A 1 486 ? 10.019  13.524  26.064  1   42.579  ? 492  ASN A HD21 1 c 
ATOM   7433  H  HD22 . ASN A 1 486 ? 9.24    12.204  26.145  1   42.528  ? 492  ASN A HD22 1 c 
ATOM   7434  N  N    . LEU A 1 487 ? 9.013   10.559  32.005  1   34.638  ? 493  LEU A N    1 ? 
ATOM   7435  C  CA   . LEU A 1 487 ? 8.727   9.428   32.865  1   34.204  ? 493  LEU A CA   1 ? 
ATOM   7436  C  C    . LEU A 1 487 ? 8.654   9.957   34.29   1   34.131  ? 493  LEU A C    1 ? 
ATOM   7437  O  O    . LEU A 1 487 ? 9.219   11.011  34.58   1   33.332  ? 493  LEU A O    1 ? 
ATOM   7438  C  CB   . LEU A 1 487 ? 9.815   8.349   32.757  1   31.861  ? 493  LEU A CB   1 ? 
ATOM   7439  C  CG   . LEU A 1 487 ? 9.719   7.432   31.53   1   37.074  ? 493  LEU A CG   1 ? 
ATOM   7440  C  CD1  . LEU A 1 487 ? 10.855  6.464   31.365  1   35.459  ? 493  LEU A CD1  1 ? 
ATOM   7441  C  CD2  . LEU A 1 487 ? 8.385   6.676   31.513  1   37.613  ? 493  LEU A CD2  1 ? 
ATOM   7442  H  H    . LEU A 1 487 ? 9.498   11.251  32.353  1   35.257  ? 493  LEU A H    1 c 
ATOM   7443  H  HA   . LEU A 1 487 ? 7.849   9.049   32.613  1   33.917  ? 493  LEU A HA   1 c 
ATOM   7444  H  HB2  . LEU A 1 487 ? 10.692  8.796   32.743  1   33.52   ? 493  LEU A HB2  1 c 
ATOM   7445  H  HB3  . LEU A 1 487 ? 9.776   7.789   33.567  1   33.557  ? 493  LEU A HB3  1 c 
ATOM   7446  H  HG   . LEU A 1 487 ? 9.726   8.015   30.727  1   35.85   ? 493  LEU A HG   1 c 
ATOM   7447  H  HD11 . LEU A 1 487 ? 11.681  6.955   31.215  1   35.948  ? 493  LEU A HD11 1 c 
ATOM   7448  H  HD12 . LEU A 1 487 ? 10.682  5.884   30.605  1   35.962  ? 493  LEU A HD12 1 c 
ATOM   7449  H  HD13 . LEU A 1 487 ? 10.943  5.926   32.169  1   35.979  ? 493  LEU A HD13 1 c 
ATOM   7450  H  HD21 . LEU A 1 487 ? 7.659   7.298   31.341  1   37.394  ? 493  LEU A HD21 1 c 
ATOM   7451  H  HD22 . LEU A 1 487 ? 8.244   6.244   32.372  1   37.43   ? 493  LEU A HD22 1 c 
ATOM   7452  H  HD23 . LEU A 1 487 ? 8.402   6.004   30.813  1   37.388  ? 493  LEU A HD23 1 c 
ATOM   7453  N  N    . PRO A 1 488 ? 7.987   9.23    35.207  1   38.246  ? 494  PRO A N    1 ? 
ATOM   7454  C  CA   . PRO A 1 488 ? 8.093   9.509   36.638  1   43.223  ? 494  PRO A CA   1 ? 
ATOM   7455  C  C    . PRO A 1 488 ? 9.311   8.852   37.283  1   40.448  ? 494  PRO A C    1 ? 
ATOM   7456  O  O    . PRO A 1 488 ? 9.703   7.773   36.87   1   37.702  ? 494  PRO A O    1 ? 
ATOM   7457  C  CB   . PRO A 1 488 ? 6.782   8.877   37.161  1   42.707  ? 494  PRO A CB   1 ? 
ATOM   7458  C  CG   . PRO A 1 488 ? 6.65    7.606   36.334  1   44.648  ? 494  PRO A CG   1 ? 
ATOM   7459  C  CD   . PRO A 1 488 ? 7.107   8.084   34.934  1   40.226  ? 494  PRO A CD   1 ? 
ATOM   7460  H  HA   . PRO A 1 488 ? 8.091   10.483  36.798  1   41.494  ? 494  PRO A HA   1 c 
ATOM   7461  H  HB2  . PRO A 1 488 ? 6.847   8.669   38.123  1   43.229  ? 494  PRO A HB2  1 c 
ATOM   7462  H  HB3  . PRO A 1 488 ? 6.015   9.478   37.01   1   43.216  ? 494  PRO A HB3  1 c 
ATOM   7463  H  HG2  . PRO A 1 488 ? 7.231   6.895   36.675  1   43.135  ? 494  PRO A HG2  1 c 
ATOM   7464  H  HG3  . PRO A 1 488 ? 5.724   7.288   36.314  1   43.124  ? 494  PRO A HG3  1 c 
ATOM   7465  H  HD2  . PRO A 1 488 ? 7.594   7.371   34.463  1   40.59   ? 494  PRO A HD2  1 c 
ATOM   7466  H  HD3  . PRO A 1 488 ? 6.336   8.356   34.388  1   40.657  ? 494  PRO A HD3  1 c 
ATOM   7467  N  N    . MET A 1 489 ? 9.82    9.511   38.331  1   42.208  ? 495  MET A N    1 ? 
ATOM   7468  C  CA   . MET A 1 489 ? 10.684  8.95    39.366  1   45.661  ? 495  MET A CA   1 ? 
ATOM   7469  C  C    . MET A 1 489 ? 9.83    8.574   40.571  1   41.365  ? 495  MET A C    1 ? 
ATOM   7470  O  O    . MET A 1 489 ? 9.326   9.44    41.284  1   40.627  ? 495  MET A O    1 ? 
ATOM   7471  C  CB   . MET A 1 489 ? 11.736  9.98    39.798  1   40.353  ? 495  MET A CB   1 ? 
ATOM   7472  C  CG   . MET A 1 489 ? 12.663  10.397  38.642  1   39.63   ? 495  MET A CG   1 ? 
ATOM   7473  S  SD   . MET A 1 489 ? 13.668  11.833  39.057  1   46.048  ? 495  MET A SD   1 ? 
ATOM   7474  C  CE   . MET A 1 489 ? 14.908  11.01   40.065  1   53.976  ? 495  MET A CE   1 ? 
ATOM   7475  H  H    . MET A 1 489 ? 9.609   10.398  38.404  1   42.518  ? 495  MET A H    1 c 
ATOM   7476  H  HA   . MET A 1 489 ? 11.131  8.142   39.008  1   43.104  ? 495  MET A HA   1 c 
ATOM   7477  H  HB2  . MET A 1 489 ? 11.279  10.774  40.147  1   41.329  ? 495  MET A HB2  1 c 
ATOM   7478  H  HB3  . MET A 1 489 ? 12.275  9.597   40.523  1   41.333  ? 495  MET A HB3  1 c 
ATOM   7479  H  HG2  . MET A 1 489 ? 13.255  9.652   38.415  1   40.959  ? 495  MET A HG2  1 c 
ATOM   7480  H  HG3  . MET A 1 489 ? 12.126  10.606  37.852  1   40.966  ? 495  MET A HG3  1 c 
ATOM   7481  H  HE1  . MET A 1 489 ? 15.611  11.644  40.298  1   51.86   ? 495  MET A HE1  1 c 
ATOM   7482  H  HE2  . MET A 1 489 ? 14.492  10.672  40.879  1   51.86   ? 495  MET A HE2  1 c 
ATOM   7483  H  HE3  . MET A 1 489 ? 15.292  10.266  39.565  1   51.811  ? 495  MET A HE3  1 c 
ATOM   7484  N  N    . ILE A 1 490 ? 9.587   7.274   40.706  1   38.487  ? 496  ILE A N    1 ? 
ATOM   7485  C  CA   . ILE A 1 490 ? 8.611   6.738   41.64   1   40.504  ? 496  ILE A CA   1 ? 
ATOM   7486  C  C    . ILE A 1 490 ? 9.262   6.647   43.016  1   43.811  ? 496  ILE A C    1 ? 
ATOM   7487  O  O    . ILE A 1 490 ? 10.291  5.961   43.171  1   41.843  ? 496  ILE A O    1 ? 
ATOM   7488  C  CB   . ILE A 1 490 ? 8.117   5.365   41.159  1   38.487  ? 496  ILE A CB   1 ? 
ATOM   7489  C  CG1  . ILE A 1 490 ? 7.566   5.442   39.737  1   40.288  ? 496  ILE A CG1  1 ? 
ATOM   7490  C  CG2  . ILE A 1 490 ? 7.115   4.8     42.16   1   43.465  ? 496  ILE A CG2  1 ? 
ATOM   7491  C  CD1  . ILE A 1 490 ? 7.143   4.125   39.114  1   38.066  ? 496  ILE A CD1  1 ? 
ATOM   7492  H  H    . ILE A 1 490 ? 10.067  6.685   40.198  1   39.672  ? 496  ILE A H    1 c 
ATOM   7493  H  HA   . ILE A 1 490 ? 7.848   7.347   41.684  1   40.385  ? 496  ILE A HA   1 c 
ATOM   7494  H  HB   . ILE A 1 490 ? 8.89    4.765   41.141  1   40.089  ? 496  ILE A HB   1 c 
ATOM   7495  H  HG12 . ILE A 1 490 ? 6.793   6.042   39.741  1   39.337  ? 496  ILE A HG12 1 c 
ATOM   7496  H  HG13 . ILE A 1 490 ? 8.247   5.846   39.162  1   39.347  ? 496  ILE A HG13 1 c 
ATOM   7497  H  HG21 . ILE A 1 490 ? 6.769   3.953   41.833  1   41.895  ? 496  ILE A HG21 1 c 
ATOM   7498  H  HG22 . ILE A 1 490 ? 6.38    5.425   42.273  1   41.928  ? 496  ILE A HG22 1 c 
ATOM   7499  H  HG23 . ILE A 1 490 ? 7.552   4.657   43.016  1   41.937  ? 496  ILE A HG23 1 c 
ATOM   7500  H  HD11 . ILE A 1 490 ? 7.862   3.472   39.213  1   38.726  ? 496  ILE A HD11 1 c 
ATOM   7501  H  HD12 . ILE A 1 490 ? 6.954   4.258   38.166  1   38.72   ? 496  ILE A HD12 1 c 
ATOM   7502  H  HD13 . ILE A 1 490 ? 6.341   3.793   39.56   1   38.753  ? 496  ILE A HD13 1 c 
ATOM   7503  N  N    . ASN A 1 491 ? 8.653   7.357   43.984  1   47.068  ? 497  ASN A N    1 ? 
ATOM   7504  C  CA   . ASN A 1 491 ? 9.227   7.58    45.305  1   43.26   ? 497  ASN A CA   1 ? 
ATOM   7505  C  C    . ASN A 1 491 ? 10.6    8.242   45.135  1   52.71   ? 497  ASN A C    1 ? 
ATOM   7506  O  O    . ASN A 1 491 ? 11.497  7.966   45.917  1   52.515  ? 497  ASN A O    1 ? 
ATOM   7507  C  CB   . ASN A 1 491 ? 9.272   6.293   46.136  1   49.816  ? 497  ASN A CB   1 ? 
ATOM   7508  C  CG   . ASN A 1 491 ? 8.074   6.037   47.048  1   50.099  ? 497  ASN A CG   1 ? 
ATOM   7509  O  OD1  . ASN A 1 491 ? 7.483   6.956   47.633  1   40.505  ? 497  ASN A OD1  1 ? 
ATOM   7510  N  ND2  . ASN A 1 491 ? 7.692   4.77    47.185  1   46.733  ? 497  ASN A ND2  1 ? 
ATOM   7511  H  H    . ASN A 1 491 ? 7.831   7.717   43.808  1   45.312  ? 497  ASN A H    1 c 
ATOM   7512  H  HA   . ASN A 1 491 ? 8.645   8.214   45.78   1   46.837  ? 497  ASN A HA   1 c 
ATOM   7513  H  HB2  . ASN A 1 491 ? 9.36    5.534   45.526  1   48.233  ? 497  ASN A HB2  1 c 
ATOM   7514  H  HB3  . ASN A 1 491 ? 10.077  6.309   46.692  1   48.343  ? 497  ASN A HB3  1 c 
ATOM   7515  H  HD21 . ASN A 1 491 ? 7.069   4.56    47.781  1   47.695  ? 497  ASN A HD21 1 c 
ATOM   7516  H  HD22 . ASN A 1 491 ? 8.055   4.136   46.682  1   47.779  ? 497  ASN A HD22 1 c 
ATOM   7517  N  N    . GLY A 1 492 ? 10.77   9.083   44.089  1   48.248  ? 498  GLY A N    1 ? 
ATOM   7518  C  CA   . GLY A 1 492 ? 12.054  9.67    43.726  1   41.196  ? 498  GLY A CA   1 ? 
ATOM   7519  C  C    . GLY A 1 492 ? 13.099  8.645   43.262  1   41.064  ? 498  GLY A C    1 ? 
ATOM   7520  O  O    . GLY A 1 492 ? 14.283  8.884   43.337  1   43.756  ? 498  GLY A O    1 ? 
ATOM   7521  H  H    . GLY A 1 492 ? 10.039  9.311   43.589  1   47.487  ? 498  GLY A H    1 c 
ATOM   7522  H  HA2  . GLY A 1 492 ? 11.907  10.327  43.006  1   42.753  ? 498  GLY A HA2  1 c 
ATOM   7523  H  HA3  . GLY A 1 492 ? 12.408  10.158  44.506  1   42.753  ? 498  GLY A HA3  1 c 
ATOM   7524  N  N    . VAL A 1 493 ? 12.702  7.482   42.775  1   42.425  ? 499  VAL A N    1 ? 
ATOM   7525  C  CA   . VAL A 1 493 ? 13.674  6.524   42.27   1   45.234  ? 499  VAL A CA   1 ? 
ATOM   7526  C  C    . VAL A 1 493 ? 13.45   6.34    40.764  1   47.282  ? 499  VAL A C    1 ? 
ATOM   7527  O  O    . VAL A 1 493 ? 12.314  6.124   40.339  1   46.141  ? 499  VAL A O    1 ? 
ATOM   7528  C  CB   . VAL A 1 493 ? 13.506  5.196   43.027  1   43.716  ? 499  VAL A CB   1 ? 
ATOM   7529  C  CG1  . VAL A 1 493 ? 14.501  4.141   42.592  1   43.468  ? 499  VAL A CG1  1 ? 
ATOM   7530  C  CG2  . VAL A 1 493 ? 13.561  5.396   44.537  1   51.771  ? 499  VAL A CG2  1 ? 
ATOM   7531  H  H    . VAL A 1 493 ? 11.814  7.275   42.741  1   42.788  ? 499  VAL A H    1 c 
ATOM   7532  H  HA   . VAL A 1 493 ? 14.573  6.866   42.424  1   44.849  ? 499  VAL A HA   1 c 
ATOM   7533  H  HB   . VAL A 1 493 ? 12.608  4.854   42.809  1   45.337  ? 499  VAL A HB   1 c 
ATOM   7534  H  HG11 . VAL A 1 493 ? 15.404  4.487   42.69   1   43.588  ? 499  VAL A HG11 1 c 
ATOM   7535  H  HG12 . VAL A 1 493 ? 14.344  3.906   41.663  1   43.547  ? 499  VAL A HG12 1 c 
ATOM   7536  H  HG13 . VAL A 1 493 ? 14.398  3.349   43.146  1   43.585  ? 499  VAL A HG13 1 c 
ATOM   7537  H  HG21 . VAL A 1 493 ? 13.54   4.531   44.981  1   49.205  ? 499  VAL A HG21 1 c 
ATOM   7538  H  HG22 . VAL A 1 493 ? 12.798  5.923   44.825  1   49.218  ? 499  VAL A HG22 1 c 
ATOM   7539  H  HG23 . VAL A 1 493 ? 14.382  5.859   44.774  1   49.237  ? 499  VAL A HG23 1 c 
ATOM   7540  N  N    . PRO A 1 494 ? 14.523  6.376   39.934  1   52.376  ? 500  PRO A N    1 ? 
ATOM   7541  C  CA   . PRO A 1 494 ? 14.424  6.155   38.482  1   42.648  ? 500  PRO A CA   1 ? 
ATOM   7542  C  C    . PRO A 1 494 ? 14.393  4.672   38.154  1   37.73   ? 500  PRO A C    1 ? 
ATOM   7543  O  O    . PRO A 1 494 ? 14.513  3.858   39.06   1   38.458  ? 500  PRO A O    1 ? 
ATOM   7544  C  CB   . PRO A 1 494 ? 15.731  6.822   37.986  1   46.713  ? 500  PRO A CB   1 ? 
ATOM   7545  C  CG   . PRO A 1 494 ? 16.753  6.454   39.068  1   46.595  ? 500  PRO A CG   1 ? 
ATOM   7546  C  CD   . PRO A 1 494 ? 15.925  6.582   40.365  1   49.968  ? 500  PRO A CD   1 ? 
ATOM   7547  H  HA   . PRO A 1 494 ? 13.633  6.619   38.109  1   44.096  ? 500  PRO A HA   1 c 
ATOM   7548  H  HB2  . PRO A 1 494 ? 16      6.463   37.108  1   45.704  ? 500  PRO A HB2  1 c 
ATOM   7549  H  HB3  . PRO A 1 494 ? 15.624  7.799   37.918  1   45.732  ? 500  PRO A HB3  1 c 
ATOM   7550  H  HG2  . PRO A 1 494 ? 17.085  5.54    38.948  1   47.304  ? 500  PRO A HG2  1 c 
ATOM   7551  H  HG3  . PRO A 1 494 ? 17.51   7.077   39.068  1   47.342  ? 500  PRO A HG3  1 c 
ATOM   7552  H  HD2  . PRO A 1 494 ? 16.196  5.901   41.019  1   49.639  ? 500  PRO A HD2  1 c 
ATOM   7553  H  HD3  . PRO A 1 494 ? 16.042  7.472   40.766  1   49.689  ? 500  PRO A HD3  1 c 
ATOM   7554  N  N    . GLN A 1 495 ? 14.277  4.335   36.857  1   41.32   ? 501  GLN A N    1 ? 
ATOM   7555  C  CA   . GLN A 1 495 ? 14.329  2.96    36.381  1   45.324  ? 501  GLN A CA   1 ? 
ATOM   7556  C  C    . GLN A 1 495 ? 15.753  2.395   36.463  1   41.527  ? 501  GLN A C    1 ? 
ATOM   7557  O  O    . GLN A 1 495 ? 16.723  3.126   36.566  1   42.174  ? 501  GLN A O    1 ? 
ATOM   7558  C  CB   . GLN A 1 495 ? 13.775  2.871   34.961  1   44.421  ? 501  GLN A CB   1 ? 
ATOM   7559  C  CG   . GLN A 1 495 ? 12.3    3.257   34.863  1   42.953  ? 501  GLN A CG   1 ? 
ATOM   7560  C  CD   . GLN A 1 495 ? 11.718  3.129   33.469  1   45.481  ? 501  GLN A CD   1 ? 
ATOM   7561  O  OE1  . GLN A 1 495 ? 12.302  2.533   32.544  1   43.231  ? 501  GLN A OE1  1 ? 
ATOM   7562  N  NE2  . GLN A 1 495 ? 10.534  3.703   33.316  1   43.37   ? 501  GLN A NE2  1 ? 
ATOM   7563  H  H    . GLN A 1 495 ? 14.162  5.002   36.242  1   41.344  ? 501  GLN A H    1 c 
ATOM   7564  H  HA   . GLN A 1 495 ? 13.747  2.412   36.968  1   43.572  ? 501  GLN A HA   1 c 
ATOM   7565  H  HB2  . GLN A 1 495 ? 14.298  3.461   34.38   1   44.234  ? 501  GLN A HB2  1 c 
ATOM   7566  H  HB3  . GLN A 1 495 ? 13.887  1.954   34.635  1   44.256  ? 501  GLN A HB3  1 c 
ATOM   7567  H  HG2  . GLN A 1 495 ? 11.78   2.689   35.471  1   43.827  ? 501  GLN A HG2  1 c 
ATOM   7568  H  HG3  . GLN A 1 495 ? 12.192  4.185   35.162  1   43.821  ? 501  GLN A HG3  1 c 
ATOM   7569  H  HE21 . GLN A 1 495 ? 10.123  3.661   32.532  1   43.993  ? 501  GLN A HE21 1 c 
ATOM   7570  H  HE22 . GLN A 1 495 ? 10.151  4.127   33.995  1   43.965  ? 501  GLN A HE22 1 c 
ATOM   7571  N  N    . SER A 1 496 ? 15.859  1.075   36.445  1   38.729  ? 502  SER A N    1 ? 
ATOM   7572  C  CA   . SER A 1 496 ? 17.138  0.403   36.61   1   46.833  ? 502  SER A CA   1 ? 
ATOM   7573  C  C    . SER A 1 496 ? 17.441  -0.383  35.346  1   49.268  ? 502  SER A C    1 ? 
ATOM   7574  O  O    . SER A 1 496 ? 16.512  -0.85   34.671  1   49.36   ? 502  SER A O    1 ? 
ATOM   7575  C  CB   . SER A 1 496 ? 17.157  -0.52   37.824  1   52.615  ? 502  SER A CB   1 ? 
ATOM   7576  O  OG   . SER A 1 496 ? 17.321  0.199   39.048  1   56.978  ? 502  SER A OG   1 ? 
ATOM   7577  H  H    . SER A 1 496 ? 15.108  0.567   36.325  1   41.151  ? 502  SER A H    1 c 
ATOM   7578  H  HA   . SER A 1 496 ? 17.84   1.088   36.728  1   46.574  ? 502  SER A HA   1 c 
ATOM   7579  H  HB2  . SER A 1 496 ? 16.321  -1.022  37.856  1   52.237  ? 502  SER A HB2  1 c 
ATOM   7580  H  HB3  . SER A 1 496 ? 17.887  -1.16   37.728  1   52.224  ? 502  SER A HB3  1 c 
ATOM   7581  H  HG   . SER A 1 496 ? 17.299  -0.332  39.699  0   56.71   ? 502  SER A HG   1 c 
ATOM   7582  N  N    . PHE A 1 497 ? 18.743  -0.492  35.04   1   51.735  ? 503  PHE A N    1 ? 
ATOM   7583  C  CA   . PHE A 1 497 ? 19.222  -1.284  33.911  1   51.127  ? 503  PHE A CA   1 ? 
ATOM   7584  C  C    . PHE A 1 497 ? 18.947  -2.758  34.172  1   48.381  ? 503  PHE A C    1 ? 
ATOM   7585  O  O    . PHE A 1 497 ? 19.08   -3.207  35.302  1   53.569  ? 503  PHE A O    1 ? 
ATOM   7586  C  CB   . PHE A 1 497 ? 20.731  -1.102  33.668  1   53.44   ? 503  PHE A CB   1 ? 
ATOM   7587  C  CG   . PHE A 1 497 ? 21.332  -2.219  32.828  1   54.242  ? 503  PHE A CG   1 ? 
ATOM   7588  C  CD1  . PHE A 1 497 ? 21.098  -2.276  31.453  1   56.911  ? 503  PHE A CD1  1 ? 
ATOM   7589  C  CD2  . PHE A 1 497 ? 22.112  -3.219  33.417  1   56.937  ? 503  PHE A CD2  1 ? 
ATOM   7590  C  CE1  . PHE A 1 497 ? 21.64   -3.304  30.679  1   60.118  ? 503  PHE A CE1  1 ? 
ATOM   7591  C  CE2  . PHE A 1 497 ? 22.653  -4.242  32.642  1   63.535  ? 503  PHE A CE2  1 ? 
ATOM   7592  C  CZ   . PHE A 1 497 ? 22.418  -4.283  31.275  1   64.707  ? 503  PHE A CZ   1 ? 
ATOM   7593  H  H    . PHE A 1 497 ? 19.358  -0.055  35.557  1   50.963  ? 503  PHE A H    1 c 
ATOM   7594  H  HA   . PHE A 1 497 ? 18.73   -1.003  33.095  1   51.117  ? 503  PHE A HA   1 c 
ATOM   7595  H  HB2  . PHE A 1 497 ? 20.876  -0.244  33.213  1   53.096  ? 503  PHE A HB2  1 c 
ATOM   7596  H  HB3  . PHE A 1 497 ? 21.189  -1.072  34.537  1   53.124  ? 503  PHE A HB3  1 c 
ATOM   7597  H  HD1  . PHE A 1 497 ? 20.57   -1.61   31.043  1   57.076  ? 503  PHE A HD1  1 c 
ATOM   7598  H  HD2  . PHE A 1 497 ? 22.277  -3.195  34.346  1   57.767  ? 503  PHE A HD2  1 c 
ATOM   7599  H  HE1  . PHE A 1 497 ? 21.479  -3.328  29.75   1   60.149  ? 503  PHE A HE1  1 c 
ATOM   7600  H  HE2  . PHE A 1 497 ? 23.183  -4.909  33.049  1   62.086  ? 503  PHE A HE2  1 c 
ATOM   7601  H  HZ   . PHE A 1 497 ? 22.786  -4.978  30.753  1   63.177  ? 503  PHE A HZ   1 c 
ATOM   7602  N  N    . GLY A 1 498 ? 18.594  -3.503  33.121  1   49.743  ? 504  GLY A N    1 ? 
ATOM   7603  C  CA   . GLY A 1 498 ? 18.554  -4.954  33.197  1   45.174  ? 504  GLY A CA   1 ? 
ATOM   7604  C  C    . GLY A 1 498 ? 17.423  -5.507  32.339  1   45.855  ? 504  GLY A C    1 ? 
ATOM   7605  O  O    . GLY A 1 498 ? 16.405  -4.847  32.143  1   44.803  ? 504  GLY A O    1 ? 
ATOM   7606  H  H    . GLY A 1 498 ? 18.372  -3.096  32.333  1   48.369  ? 504  GLY A H    1 c 
ATOM   7607  H  HA2  . GLY A 1 498 ? 19.416  -5.318  32.886  1   46.405  ? 504  GLY A HA2  1 c 
ATOM   7608  H  HA3  . GLY A 1 498 ? 18.425  -5.233  34.133  1   46.469  ? 504  GLY A HA3  1 c 
ATOM   7609  N  N    . GLN A 1 499 ? 17.632  -6.714  31.813  1   46.095  ? 505  GLN A N    1 ? 
ATOM   7610  C  CA   . GLN A 1 499 ? 16.669  -7.42   30.98   1   54.046  ? 505  GLN A CA   1 ? 
ATOM   7611  C  C    . GLN A 1 499 ? 15.308  -7.556  31.68   1   48.496  ? 505  GLN A C    1 ? 
ATOM   7612  O  O    . GLN A 1 499 ? 14.279  -7.509  31.017  1   53.359  ? 505  GLN A O    1 ? 
ATOM   7613  C  CB   . GLN A 1 499 ? 17.274  -8.785  30.621  1   59.042  ? 505  GLN A CB   1 ? 
ATOM   7614  C  CG   . GLN A 1 499 ? 16.407  -9.66   29.715  1   59.734  ? 505  GLN A CG   1 ? 
ATOM   7615  C  CD   . GLN A 1 499 ? 16.739  -9.529  28.245  1   67.074  ? 505  GLN A CD   1 ? 
ATOM   7616  O  OE1  . GLN A 1 499 ? 17.732  -8.904  27.845  1   66.206  ? 505  GLN A OE1  1 ? 
ATOM   7617  N  NE2  . GLN A 1 499 ? 15.91   -10.149 27.423  1   66.884  ? 505  GLN A NE2  1 ? 
ATOM   7618  H  H    . GLN A 1 499 ? 18.429  -7.126  31.987  1   47.846  ? 505  GLN A H    1 c 
ATOM   7619  H  HA   . GLN A 1 499 ? 16.543  -6.9    30.146  1   52.197  ? 505  GLN A HA   1 c 
ATOM   7620  H  HB2  . GLN A 1 499 ? 18.139  -8.636  30.188  1   57.973  ? 505  GLN A HB2  1 c 
ATOM   7621  H  HB3  . GLN A 1 499 ? 17.444  -9.272  31.454  1   58.01   ? 505  GLN A HB3  1 c 
ATOM   7622  H  HG2  . GLN A 1 499 ? 16.519  -10.599 29.976  1   61.169  ? 505  GLN A HG2  1 c 
ATOM   7623  H  HG3  . GLN A 1 499 ? 15.464  -9.429  29.842  1   61.071  ? 505  GLN A HG3  1 c 
ATOM   7624  H  HE21 . GLN A 1 499 ? 16.03   -10.088 26.546  1   66.924  ? 505  GLN A HE21 1 c 
ATOM   7625  H  HE22 . GLN A 1 499 ? 15.235  -10.626 27.746  1   66.885  ? 505  GLN A HE22 1 c 
ATOM   7626  N  N    . ASN A 1 500 ? 15.286  -7.733  33.008  1   49.184  ? 506  ASN A N    1 ? 
ATOM   7627  C  CA   . ASN A 1 500 ? 14.049  -8.058  33.704  1   54.663  ? 506  ASN A CA   1 ? 
ATOM   7628  C  C    . ASN A 1 500 ? 13.412  -6.8    34.289  1   49.725  ? 506  ASN A C    1 ? 
ATOM   7629  O  O    . ASN A 1 500 ? 12.423  -6.903  35.005  1   53.615  ? 506  ASN A O    1 ? 
ATOM   7630  C  CB   . ASN A 1 500 ? 14.251  -9.179  34.724  1   63.611  ? 506  ASN A CB   1 ? 
ATOM   7631  C  CG   . ASN A 1 500 ? 14.645  -10.479 34.054  1   64.135  ? 506  ASN A CG   1 ? 
ATOM   7632  O  OD1  . ASN A 1 500 ? 14.029  -10.877 33.059  1   65.116  ? 506  ASN A OD1  1 ? 
ATOM   7633  N  ND2  . ASN A 1 500 ? 15.695  -11.128 34.534  1   61.225  ? 506  ASN A ND2  1 ? 
ATOM   7634  H  H    . ASN A 1 500 ? 16.059  -7.66   33.49   1   50.167  ? 506  ASN A H    1 c 
ATOM   7635  H  HA   . ASN A 1 500 ? 13.42   -8.406  33.033  1   54.197  ? 506  ASN A HA   1 c 
ATOM   7636  H  HB2  . ASN A 1 500 ? 14.948  -8.917  35.358  1   61.572  ? 506  ASN A HB2  1 c 
ATOM   7637  H  HB3  . ASN A 1 500 ? 13.421  -9.315  35.224  1   61.535  ? 506  ASN A HB3  1 c 
ATOM   7638  H  HD21 . ASN A 1 500 ? 15.962  -11.881 34.148  1   62.13   ? 506  ASN A HD21 1 c 
ATOM   7639  H  HD22 . ASN A 1 500 ? 16.132  -10.814 35.239  1   62.117  ? 506  ASN A HD22 1 c 
ATOM   7640  N  N    . TYR A 1 501 ? 13.949  -5.619  33.951  1   45.86   ? 507  TYR A N    1 ? 
ATOM   7641  C  CA   . TYR A 1 501 ? 13.233  -4.368  34.136  1   43.618  ? 507  TYR A CA   1 ? 
ATOM   7642  C  C    . TYR A 1 501 ? 12.453  -4.077  32.859  1   43.377  ? 507  TYR A C    1 ? 
ATOM   7643  O  O    . TYR A 1 501 ? 13.027  -3.599  31.874  1   47.686  ? 507  TYR A O    1 ? 
ATOM   7644  C  CB   . TYR A 1 501 ? 14.242  -3.3    34.561  1   48.849  ? 507  TYR A CB   1 ? 
ATOM   7645  C  CG   . TYR A 1 501 ? 14.854  -3.613  35.92   1   56.001  ? 507  TYR A CG   1 ? 
ATOM   7646  C  CD1  . TYR A 1 501 ? 14.088  -3.484  37.077  1   53.078  ? 507  TYR A CD1  1 ? 
ATOM   7647  C  CD2  . TYR A 1 501 ? 16.174  -4.047  36.054  1   52.882  ? 507  TYR A CD2  1 ? 
ATOM   7648  C  CE1  . TYR A 1 501 ? 14.615  -3.751  38.325  1   46.514  ? 507  TYR A CE1  1 ? 
ATOM   7649  C  CE2  . TYR A 1 501 ? 16.704  -4.347  37.303  1   50.872  ? 507  TYR A CE2  1 ? 
ATOM   7650  C  CZ   . TYR A 1 501 ? 15.918  -4.207  38.437  1   54.902  ? 507  TYR A CZ   1 ? 
ATOM   7651  O  OH   . TYR A 1 501 ? 16.398  -4.464  39.686  1   49.026  ? 507  TYR A OH   1 ? 
ATOM   7652  H  H    . TYR A 1 501 ? 14.794  -5.592  33.606  1   46.347  ? 507  TYR A H    1 c 
ATOM   7653  H  HA   . TYR A 1 501 ? 12.586  -4.487  34.877  1   45.039  ? 507  TYR A HA   1 c 
ATOM   7654  H  HB2  . TYR A 1 501 ? 14.956  -3.25   33.887  1   49.089  ? 507  TYR A HB2  1 c 
ATOM   7655  H  HB3  . TYR A 1 501 ? 13.788  -2.43   34.602  1   49.087  ? 507  TYR A HB3  1 c 
ATOM   7656  H  HD1  . TYR A 1 501 ? 13.196  -3.183  37.009  1   52.07   ? 507  TYR A HD1  1 c 
ATOM   7657  H  HD2  . TYR A 1 501 ? 16.707  -4.16   35.284  1   52.923  ? 507  TYR A HD2  1 c 
ATOM   7658  H  HE1  . TYR A 1 501 ? 14.079  -3.662  39.093  1   49.852  ? 507  TYR A HE1  1 c 
ATOM   7659  H  HE2  . TYR A 1 501 ? 17.596  -4.639  37.381  1   52.209  ? 507  TYR A HE2  1 c 
ATOM   7660  H  HH   . TYR A 1 501 ? 16.223  -5.271  39.912  0   49.57   ? 507  TYR A HH   1 c 
ATOM   7661  N  N    . LYS A 1 502 ? 11.155  -4.409  32.885  1   45.357  ? 508  LYS A N    1 ? 
ATOM   7662  C  CA   . LYS A 1 502 ? 10.312  -4.43   31.696  1   40.771  ? 508  LYS A CA   1 ? 
ATOM   7663  C  C    . LYS A 1 502 ? 8.911   -3.89   31.982  1   40.452  ? 508  LYS A C    1 ? 
ATOM   7664  O  O    . LYS A 1 502 ? 8.439   -3.888  33.116  1   46.106  ? 508  LYS A O    1 ? 
ATOM   7665  C  CB   . LYS A 1 502 ? 10.199  -5.846  31.13   1   45.761  ? 508  LYS A CB   1 ? 
ATOM   7666  C  CG   . LYS A 1 502 ? 9.729   -6.906  32.11   1   57.027  ? 508  LYS A CG   1 ? 
ATOM   7667  C  CD   . LYS A 1 502 ? 9.332   -8.261  31.515  1   63.198  ? 508  LYS A CD   1 ? 
ATOM   7668  C  CE   . LYS A 1 502 ? 8.582   -9.043  32.572  1   69.413  ? 508  LYS A CE   1 ? 
ATOM   7669  N  NZ   . LYS A 1 502 ? 7.822   -10.215 32.127  1   64.774  ? 508  LYS A NZ   1 ? 
ATOM   7670  H  H    . LYS A 1 502 ? 10.775  -4.633  33.686  1   43.797  ? 508  LYS A H    1 c 
ATOM   7671  H  HA   . LYS A 1 502 ? 10.73   -3.853  31.011  1   42.503  ? 508  LYS A HA   1 c 
ATOM   7672  H  HB2  . LYS A 1 502 ? 9.576   -5.831  30.372  1   46.859  ? 508  LYS A HB2  1 c 
ATOM   7673  H  HB3  . LYS A 1 502 ? 11.077  -6.115  30.785  1   46.88   ? 508  LYS A HB3  1 c 
ATOM   7674  H  HG2  . LYS A 1 502 ? 10.447  -7.053  32.764  1   55.429  ? 508  LYS A HG2  1 c 
ATOM   7675  H  HG3  . LYS A 1 502 ? 8.961   -6.544  32.603  1   55.522  ? 508  LYS A HG3  1 c 
ATOM   7676  H  HD2  . LYS A 1 502 ? 8.755   -8.128  30.732  1   63.097  ? 508  LYS A HD2  1 c 
ATOM   7677  H  HD3  . LYS A 1 502 ? 10.135  -8.758  31.245  1   63.098  ? 508  LYS A HD3  1 c 
ATOM   7678  H  HE2  . LYS A 1 502 ? 9.224   -9.338  33.243  1   66.807  ? 508  LYS A HE2  1 c 
ATOM   7679  H  HE3  . LYS A 1 502 ? 7.96    -8.441  33.02   1   66.685  ? 508  LYS A HE3  1 c 
ATOM   7680  H  HZ1  . LYS A 1 502 ? 8.384   -10.822 31.759  1   66.168  ? 508  LYS A HZ1  1 c 
ATOM   7681  H  HZ2  . LYS A 1 502 ? 7.208   -9.965  31.509  1   66.168  ? 508  LYS A HZ2  1 c 
ATOM   7682  H  HZ3  . LYS A 1 502 ? 7.397   -10.591 32.833  1   66.168  ? 508  LYS A HZ3  1 c 
ATOM   7683  N  N    . ALA A 1 503 ? 8.214   -3.481  30.921  1   37.265  ? 509  ALA A N    1 ? 
ATOM   7684  C  CA   . ALA A 1 503 ? 6.801   -3.172  31.018  1   43.794  ? 509  ALA A CA   1 ? 
ATOM   7685  C  C    . ALA A 1 503 ? 6.047   -4.494  31.156  1   42.036  ? 509  ALA A C    1 ? 
ATOM   7686  O  O    . ALA A 1 503 ? 6.477   -5.507  30.634  1   41.792  ? 509  ALA A O    1 ? 
ATOM   7687  C  CB   . ALA A 1 503 ? 6.327   -2.41   29.798  1   45.364  ? 509  ALA A CB   1 ? 
ATOM   7688  H  H    . ALA A 1 503 ? 8.633   -3.393  30.114  1   39.52   ? 509  ALA A H    1 c 
ATOM   7689  H  HA   . ALA A 1 503 ? 6.647   -2.625  31.837  1   42.384  ? 509  ALA A HA   1 c 
ATOM   7690  H  HB1  . ALA A 1 503 ? 6.712   -1.518  29.798  1   44.764  ? 509  ALA A HB1  1 c 
ATOM   7691  H  HB2  . ALA A 1 503 ? 6.602   -2.879  28.992  1   44.823  ? 509  ALA A HB2  1 c 
ATOM   7692  H  HB3  . ALA A 1 503 ? 5.358   -2.34   29.813  1   44.841  ? 509  ALA A HB3  1 c 
ATOM   7693  N  N    . THR A 1 504 ? 4.927   -4.458  31.869  1   39.916  ? 510  THR A N    1 ? 
ATOM   7694  C  CA   . THR A 1 504 ? 3.955   -5.542  31.869  1   37.46   ? 510  THR A CA   1 ? 
ATOM   7695  C  C    . THR A 1 504 ? 2.573   -4.93   31.639  1   38.926  ? 510  THR A C    1 ? 
ATOM   7696  O  O    . THR A 1 504 ? 2.402   -3.695  31.681  1   40.955  ? 510  THR A O    1 ? 
ATOM   7697  C  CB   . THR A 1 504 ? 4.021   -6.301  33.196  1   42.306  ? 510  THR A CB   1 ? 
ATOM   7698  O  OG1  . THR A 1 504 ? 3.842   -5.296  34.19   1   41.696  ? 510  THR A OG1  1 ? 
ATOM   7699  C  CG2  . THR A 1 504 ? 5.339   -7.022  33.43   1   42.774  ? 510  THR A CG2  1 ? 
ATOM   7700  H  H    . THR A 1 504 ? 4.756   -3.722  32.384  1   39.876  ? 510  THR A H    1 c 
ATOM   7701  H  HA   . THR A 1 504 ? 4.161   -6.16   31.135  1   39.102  ? 510  THR A HA   1 c 
ATOM   7702  H  HB   . THR A 1 504 ? 3.279   -6.95   33.247  1   41.351  ? 510  THR A HB   1 c 
ATOM   7703  H  HG1  . THR A 1 504 ? 4.493   -4.69   34.076  0   42.39   ? 510  THR A HG1  1 c 
ATOM   7704  H  HG21 . THR A 1 504 ? 5.308   -7.487  34.282  1   42.632  ? 510  THR A HG21 1 c 
ATOM   7705  H  HG22 . THR A 1 504 ? 6.066   -6.376  33.44   1   42.62   ? 510  THR A HG22 1 c 
ATOM   7706  H  HG23 . THR A 1 504 ? 5.489   -7.664  32.716  1   42.632  ? 510  THR A HG23 1 c 
ATOM   7707  N  N    . ASP A 1 505 ? 1.615   -5.82   31.356  1   41.852  ? 511  ASP A N    1 ? 
ATOM   7708  C  CA   . ASP A 1 505 ? 0.227   -5.466  31.098  1   48.295  ? 511  ASP A CA   1 ? 
ATOM   7709  C  C    . ASP A 1 505 ? 0.167   -4.416  29.996  1   42.374  ? 511  ASP A C    1 ? 
ATOM   7710  O  O    . ASP A 1 505 ? -0.571  -3.445  30.105  1   36.269  ? 511  ASP A O    1 ? 
ATOM   7711  C  CB   . ASP A 1 505 ? -0.478  -4.975  32.358  1   52.638  ? 511  ASP A CB   1 ? 
ATOM   7712  C  CG   . ASP A 1 505 ? -0.312  -5.884  33.568  1   55.231  ? 511  ASP A CG   1 ? 
ATOM   7713  O  OD1  . ASP A 1 505 ? -0.341  -7.105  33.369  1   49.902  ? 511  ASP A OD1  1 ? 
ATOM   7714  O  OD2  . ASP A 1 505 ? -0.15   -5.361  34.685  1   57.67   ? 511  ASP A OD2  1 ? 
ATOM   7715  H  H    . ASP A 1 505 ? 1.844   -6.705  31.323  1   42.431  ? 511  ASP A H    1 c 
ATOM   7716  H  HA   . ASP A 1 505 ? -0.242  -6.272  30.787  1   46.607  ? 511  ASP A HA   1 c 
ATOM   7717  H  HB2  . ASP A 1 505 ? -0.129  -4.09   32.594  1   51.982  ? 511  ASP A HB2  1 c 
ATOM   7718  H  HB3  . ASP A 1 505 ? -1.435  -4.885  32.172  1   52.053  ? 511  ASP A HB3  1 c 
ATOM   7719  N  N    . VAL A 1 506 ? 0.972   -4.615  28.945  1   50.881  ? 512  VAL A N    1 ? 
ATOM   7720  C  CA   . VAL A 1 506 ? 1.051   -3.662  27.845  1   44.833  ? 512  VAL A CA   1 ? 
ATOM   7721  C  C    . VAL A 1 506 ? -0.218  -3.773  27.005  1   45.585  ? 512  VAL A C    1 ? 
ATOM   7722  O  O    . VAL A 1 506 ? -0.587  -4.883  26.638  1   38.286  ? 512  VAL A O    1 ? 
ATOM   7723  C  CB   . VAL A 1 506 ? 2.326   -3.987  27.058  1   41.243  ? 512  VAL A CB   1 ? 
ATOM   7724  C  CG1  . VAL A 1 506 ? 2.46    -3.171  25.784  1   47.673  ? 512  VAL A CG1  1 ? 
ATOM   7725  C  CG2  . VAL A 1 506 ? 3.534   -3.795  27.941  1   41.992  ? 512  VAL A CG2  1 ? 
ATOM   7726  H  H    . VAL A 1 506 ? 1.469   -5.381  28.902  1   47.151  ? 512  VAL A H    1 c 
ATOM   7727  H  HA   . VAL A 1 506 ? 1.122   -2.76   28.211  1   45.269  ? 512  VAL A HA   1 c 
ATOM   7728  H  HB   . VAL A 1 506 ? 2.279   -4.939  26.805  1   43.205  ? 512  VAL A HB   1 c 
ATOM   7729  H  HG11 . VAL A 1 506 ? 2.377   -2.225  25.994  1   45.667  ? 512  VAL A HG11 1 c 
ATOM   7730  H  HG12 . VAL A 1 506 ? 1.761   -3.425  25.158  1   45.668  ? 512  VAL A HG12 1 c 
ATOM   7731  H  HG13 . VAL A 1 506 ? 3.329   -3.337  25.381  1   45.646  ? 512  VAL A HG13 1 c 
ATOM   7732  H  HG21 . VAL A 1 506 ? 4.343   -3.893  27.412  1   41.87   ? 512  VAL A HG21 1 c 
ATOM   7733  H  HG22 . VAL A 1 506 ? 3.531   -4.461  28.649  1   41.873  ? 512  VAL A HG22 1 c 
ATOM   7734  H  HG23 . VAL A 1 506 ? 3.511   -2.906  28.334  1   41.808  ? 512  VAL A HG23 1 c 
ATOM   7735  N  N    . VAL A 1 507 ? -0.881  -2.63   26.749  1   40.964  ? 513  VAL A N    1 ? 
ATOM   7736  C  CA   . VAL A 1 507 ? -2.106  -2.579  25.959  1   48.011  ? 513  VAL A CA   1 ? 
ATOM   7737  C  C    . VAL A 1 507 ? -1.998  -1.505  24.875  1   43.471  ? 513  VAL A C    1 ? 
ATOM   7738  O  O    . VAL A 1 507 ? -1.532  -0.405  25.128  1   41.297  ? 513  VAL A O    1 ? 
ATOM   7739  C  CB   . VAL A 1 507 ? -3.291  -2.29   26.907  1   59.032  ? 513  VAL A CB   1 ? 
ATOM   7740  C  CG1  . VAL A 1 507 ? -4.522  -1.77   26.172  1   56.907  ? 513  VAL A CG1  1 ? 
ATOM   7741  C  CG2  . VAL A 1 507 ? -3.639  -3.523  27.743  1   65.491  ? 513  VAL A CG2  1 ? 
ATOM   7742  H  H    . VAL A 1 507 ? -0.55   -1.847  27.085  1   43.577  ? 513  VAL A H    1 c 
ATOM   7743  H  HA   . VAL A 1 507 ? -2.246  -3.445  25.536  1   47.288  ? 513  VAL A HA   1 c 
ATOM   7744  H  HB   . VAL A 1 507 ? -2.997  -1.584  27.529  1   57.411  ? 513  VAL A HB   1 c 
ATOM   7745  H  HG11 . VAL A 1 507 ? -4.701  -2.331  25.398  1   57.446  ? 513  VAL A HG11 1 c 
ATOM   7746  H  HG12 . VAL A 1 507 ? -4.368  -0.856  25.881  1   57.434  ? 513  VAL A HG12 1 c 
ATOM   7747  H  HG13 . VAL A 1 507 ? -5.289  -1.792  26.769  1   57.567  ? 513  VAL A HG13 1 c 
ATOM   7748  H  HG21 . VAL A 1 507 ? -4.382  -3.316  28.334  1   63.458  ? 513  VAL A HG21 1 c 
ATOM   7749  H  HG22 . VAL A 1 507 ? -2.868  -3.785  28.273  1   63.417  ? 513  VAL A HG22 1 c 
ATOM   7750  H  HG23 . VAL A 1 507 ? -3.889  -4.254  27.153  1   63.49   ? 513  VAL A HG23 1 c 
ATOM   7751  N  N    . CYS A 1 508 ? -2.491  -1.804  23.676  1   38.065  ? 514  CYS A N    1 ? 
ATOM   7752  C  CA   . CYS A 1 508 ? -2.622  -0.803  22.633  1   41.323  ? 514  CYS A CA   1 ? 
ATOM   7753  C  C    . CYS A 1 508 ? -3.98   -0.994  21.998  1   34.641  ? 514  CYS A C    1 ? 
ATOM   7754  O  O    . CYS A 1 508 ? -4.248  -2.083  21.531  1   39.444  ? 514  CYS A O    1 ? 
ATOM   7755  C  CB   . CYS A 1 508 ? -1.55   -0.989  21.556  1   44.955  ? 514  CYS A CB   1 ? 
ATOM   7756  S  SG   . CYS A 1 508 ? -1.735  0.156   20.165  1   45.473  ? 514  CYS A SG   1 ? 
ATOM   7757  H  H    . CYS A 1 508 ? -2.752  -2.662  23.498  1   40.092  ? 514  CYS A H    1 c 
ATOM   7758  H  HA   . CYS A 1 508 ? -2.571  0.096   23.038  1   39.966  ? 514  CYS A HA   1 c 
ATOM   7759  H  HB2  . CYS A 1 508 ? -0.662  -0.858  21.956  1   44.14   ? 514  CYS A HB2  1 c 
ATOM   7760  H  HB3  . CYS A 1 508 ? -1.597  -1.908  21.213  1   44.052  ? 514  CYS A HB3  1 c 
ATOM   7761  H  HG   . CYS A 1 508 ? -0.793  -0.236  19.499  0   45.25   ? 514  CYS A HG   1 c 
ATOM   7762  N  N    . GLN A 1 509 ? -4.821  0.039   21.992  1   39.068  ? 515  GLN A N    1 ? 
ATOM   7763  C  CA   . GLN A 1 509 ? -6.105  -0.028  21.314  1   42.144  ? 515  GLN A CA   1 ? 
ATOM   7764  C  C    . GLN A 1 509 ? -6.105  0.971   20.157  1   38.224  ? 515  GLN A C    1 ? 
ATOM   7765  O  O    . GLN A 1 509 ? -6.391  2.154   20.343  1   37.863  ? 515  GLN A O    1 ? 
ATOM   7766  C  CB   . GLN A 1 509 ? -7.247  0.303   22.274  1   45.535  ? 515  GLN A CB   1 ? 
ATOM   7767  C  CG   . GLN A 1 509 ? -7.365  -0.608  23.489  1   53.529  ? 515  GLN A CG   1 ? 
ATOM   7768  C  CD   . GLN A 1 509 ? -8.535  -0.22   24.382  1   57.825  ? 515  GLN A CD   1 ? 
ATOM   7769  O  OE1  . GLN A 1 509 ? -9.437  0.534   23.99   1   62.466  ? 515  GLN A OE1  1 ? 
ATOM   7770  N  NE2  . GLN A 1 509 ? -8.549  -0.748  25.594  1   51.404  ? 515  GLN A NE2  1 ? 
ATOM   7771  H  H    . GLN A 1 509 ? -4.59   0.811   22.423  1   38.646  ? 515  GLN A H    1 c 
ATOM   7772  H  HA   . GLN A 1 509 ? -6.238  -0.942  20.959  1   41.311  ? 515  GLN A HA   1 c 
ATOM   7773  H  HB2  . GLN A 1 509 ? -7.133  1.224   22.585  1   46.298  ? 515  GLN A HB2  1 c 
ATOM   7774  H  HB3  . GLN A 1 509 ? -8.088  0.266   21.772  1   46.47   ? 515  GLN A HB3  1 c 
ATOM   7775  H  HG2  . GLN A 1 509 ? -7.484  -1.535  23.191  1   52.501  ? 515  GLN A HG2  1 c 
ATOM   7776  H  HG3  . GLN A 1 509 ? -6.536  -0.564  24.011  1   52.442  ? 515  GLN A HG3  1 c 
ATOM   7777  H  HE21 . GLN A 1 509 ? -9.227  -0.58   26.142  1   53.365  ? 515  GLN A HE21 1 c 
ATOM   7778  H  HE22 . GLN A 1 509 ? -7.883  -1.27   25.859  1   53.311  ? 515  GLN A HE22 1 c 
ATOM   7779  N  N    . PRO A 1 510 ? -5.727  0.546   18.929  1   39.531  ? 516  PRO A N    1 ? 
ATOM   7780  C  CA   . PRO A 1 510 ? -5.606  1.478   17.799  1   38.505  ? 516  PRO A CA   1 ? 
ATOM   7781  C  C    . PRO A 1 510 ? -6.81   2.38    17.568  1   44.7    ? 516  PRO A C    1 ? 
ATOM   7782  O  O    . PRO A 1 510 ? -6.658  3.592   17.403  1   42.151  ? 516  PRO A O    1 ? 
ATOM   7783  C  CB   . PRO A 1 510 ? -5.381  0.518   16.616  1   42.33   ? 516  PRO A CB   1 ? 
ATOM   7784  C  CG   . PRO A 1 510 ? -4.62   -0.63   17.226  1   38.71   ? 516  PRO A CG   1 ? 
ATOM   7785  C  CD   . PRO A 1 510 ? -5.296  -0.825  18.592  1   40.68   ? 516  PRO A CD   1 ? 
ATOM   7786  H  HA   . PRO A 1 510 ? -4.797  2.032   17.931  1   40.472  ? 516  PRO A HA   1 c 
ATOM   7787  H  HB2  . PRO A 1 510 ? -6.239  0.212   16.241  1   40.655  ? 516  PRO A HB2  1 c 
ATOM   7788  H  HB3  . PRO A 1 510 ? -4.854  0.952   15.905  1   40.625  ? 516  PRO A HB3  1 c 
ATOM   7789  H  HG2  . PRO A 1 510 ? -4.699  -1.437  16.676  1   39.945  ? 516  PRO A HG2  1 c 
ATOM   7790  H  HG3  . PRO A 1 510 ? -3.671  -0.407  17.333  1   39.945  ? 516  PRO A HG3  1 c 
ATOM   7791  H  HD2  . PRO A 1 510 ? -6.064  -1.435  18.525  1   39.969  ? 516  PRO A HD2  1 c 
ATOM   7792  H  HD3  . PRO A 1 510 ? -4.659  -1.173  19.252  1   39.96   ? 516  PRO A HD3  1 c 
ATOM   7793  N  N    . LYS A 1 511 ? -8.01   1.777   17.604  1   43.943  ? 517  LYS A N    1 ? 
ATOM   7794  C  CA   . LYS A 1 511 ? -9.261  2.501   17.43   1   45.269  ? 517  LYS A CA   1 ? 
ATOM   7795  C  C    . LYS A 1 511 ? -9.486  3.607   18.463  1   43.664  ? 517  LYS A C    1 ? 
ATOM   7796  O  O    . LYS A 1 511 ? -10.235 4.548   18.206  1   43.347  ? 517  LYS A O    1 ? 
ATOM   7797  C  CB   . LYS A 1 511 ? -10.487 1.606   17.618  1   48.087  ? 517  LYS A CB   1 ? 
ATOM   7798  C  CG   . LYS A 1 511 ? -10.66  0.428   16.689  1   52.52   ? 517  LYS A CG   1 ? 
ATOM   7799  C  CD   . LYS A 1 511 ? -11.95  -0.264  17.136  1   61.766  ? 517  LYS A CD   1 ? 
ATOM   7800  C  CE   . LYS A 1 511 ? -12.291 -1.556  16.489  1   62.268  ? 517  LYS A CE   1 ? 
ATOM   7801  N  NZ   . LYS A 1 511 ? -13.477 -2.09   17.173  1   64.983  ? 517  LYS A NZ   1 ? 
ATOM   7802  H  H    . LYS A 1 511 ? -8.046  0.875   17.742  1   44.469  ? 517  LYS A H    1 c 
ATOM   7803  H  HA   . LYS A 1 511 ? -9.272  2.898   16.524  1   45.203  ? 517  LYS A HA   1 c 
ATOM   7804  H  HB2  . LYS A 1 511 ? -10.468 1.263   18.537  1   48.534  ? 517  LYS A HB2  1 c 
ATOM   7805  H  HB3  . LYS A 1 511 ? -11.287 2.17    17.537  1   48.507  ? 517  LYS A HB3  1 c 
ATOM   7806  H  HG2  . LYS A 1 511 ? -10.742 0.74    15.761  1   53.363  ? 517  LYS A HG2  1 c 
ATOM   7807  H  HG3  . LYS A 1 511 ? -9.896  -0.183  16.773  1   53.31   ? 517  LYS A HG3  1 c 
ATOM   7808  H  HD2  . LYS A 1 511 ? -11.894 -0.412  18.106  1   59.538  ? 517  LYS A HD2  1 c 
ATOM   7809  H  HD3  . LYS A 1 511 ? -12.693 0.36    16.99   1   59.577  ? 517  LYS A HD3  1 c 
ATOM   7810  H  HE2  . LYS A 1 511 ? -12.483 -1.427  15.543  1   62.762  ? 517  LYS A HE2  1 c 
ATOM   7811  H  HE3  . LYS A 1 511 ? -11.551 -2.179  16.595  1   62.759  ? 517  LYS A HE3  1 c 
ATOM   7812  H  HZ1  . LYS A 1 511 ? -14.158 -1.494  17.125  1   64.078  ? 517  LYS A HZ1  1 c 
ATOM   7813  H  HZ2  . LYS A 1 511 ? -13.286 -2.256  18.043  1   64.077  ? 517  LYS A HZ2  1 c 
ATOM   7814  H  HZ3  . LYS A 1 511 ? -13.733 -2.863  16.775  1   64.113  ? 517  LYS A HZ3  1 c 
ATOM   7815  N  N    . LYS A 1 512 ? -8.885  3.504   19.652  1   43.117  ? 518  LYS A N    1 ? 
ATOM   7816  C  CA   . LYS A 1 512 ? -8.997  4.603   20.607  1   48.472  ? 518  LYS A CA   1 ? 
ATOM   7817  C  C    . LYS A 1 512 ? -7.714  5.436   20.71   1   44.64   ? 518  LYS A C    1 ? 
ATOM   7818  O  O    . LYS A 1 512 ? -7.67   6.351   21.523  1   40.366  ? 518  LYS A O    1 ? 
ATOM   7819  C  CB   . LYS A 1 512 ? -9.451  4.089   21.97   1   51.048  ? 518  LYS A CB   1 ? 
ATOM   7820  C  CG   . LYS A 1 512 ? -10.823 3.455   21.898  1   56.64   ? 518  LYS A CG   1 ? 
ATOM   7821  C  CD   . LYS A 1 512 ? -11.309 2.965   23.247  1   65.476  ? 518  LYS A CD   1 ? 
ATOM   7822  C  CE   . LYS A 1 512 ? -12.446 2.028   23.053  1   74.204  ? 518  LYS A CE   1 ? 
ATOM   7823  N  NZ   . LYS A 1 512 ? -12.642 1.259   24.279  1   79.056  ? 518  LYS A NZ   1 ? 
ATOM   7824  H  H    . LYS A 1 512 ? -8.416  2.754   19.879  1   44.358  ? 518  LYS A H    1 c 
ATOM   7825  H  HA   . LYS A 1 512 ? -9.714  5.207   20.289  1   47.079  ? 518  LYS A HA   1 c 
ATOM   7826  H  HB2  . LYS A 1 512 ? -8.809  3.424   22.299  1   51.652  ? 518  LYS A HB2  1 c 
ATOM   7827  H  HB3  . LYS A 1 512 ? -9.477  4.832   22.609  1   51.566  ? 518  LYS A HB3  1 c 
ATOM   7828  H  HG2  . LYS A 1 512 ? -11.458 4.116   21.546  1   57.185  ? 518  LYS A HG2  1 c 
ATOM   7829  H  HG3  . LYS A 1 512 ? -10.789 2.7     21.272  1   57.267  ? 518  LYS A HG3  1 c 
ATOM   7830  H  HD2  . LYS A 1 512 ? -10.581 2.509   23.717  1   65.359  ? 518  LYS A HD2  1 c 
ATOM   7831  H  HD3  . LYS A 1 512 ? -11.605 3.73    23.788  1   65.256  ? 518  LYS A HD3  1 c 
ATOM   7832  H  HE2  . LYS A 1 512 ? -13.259 2.526   22.851  1   73.149  ? 518  LYS A HE2  1 c 
ATOM   7833  H  HE3  . LYS A 1 512 ? -12.264 1.416   22.318  1   72.966  ? 518  LYS A HE3  1 c 
ATOM   7834  H  HZ1  . LYS A 1 512 ? -12.758 1.82    24.981  1   77.413  ? 518  LYS A HZ1  1 c 
ATOM   7835  H  HZ2  . LYS A 1 512 ? -11.92  0.734   24.433  1   77.346  ? 518  LYS A HZ2  1 c 
ATOM   7836  H  HZ3  . LYS A 1 512 ? -13.377 0.734   24.195  1   77.473  ? 518  LYS A HZ3  1 c 
ATOM   7837  N  N    . ARG A 1 513 ? -6.717  5.165   19.855  1   44.387  ? 519  ARG A N    1 ? 
ATOM   7838  C  CA   . ARG A 1 513 ? -5.41   5.825   19.89   1   45.035  ? 519  ARG A CA   1 ? 
ATOM   7839  C  C    . ARG A 1 513 ? -4.89   5.789   21.319  1   42.554  ? 519  ARG A C    1 ? 
ATOM   7840  O  O    . ARG A 1 513 ? -4.602  6.82    21.918  1   38.955  ? 519  ARG A O    1 ? 
ATOM   7841  C  CB   . ARG A 1 513 ? -5.419  7.21    19.226  1   47.036  ? 519  ARG A CB   1 ? 
ATOM   7842  C  CG   . ARG A 1 513 ? -5.611  7.083   17.708  1   48.557  ? 519  ARG A CG   1 ? 
ATOM   7843  C  CD   . ARG A 1 513 ? -5.468  8.353   16.876  1   44.624  ? 519  ARG A CD   1 ? 
ATOM   7844  N  NE   . ARG A 1 513 ? -6.414  9.39    17.31   1   41.798  ? 519  ARG A NE   1 ? 
ATOM   7845  C  CZ   . ARG A 1 513 ? -6.858  10.386  16.538  1   44.168  ? 519  ARG A CZ   1 ? 
ATOM   7846  N  NH1  . ARG A 1 513 ? -6.263  10.713  15.4    1   46.905  ? 519  ARG A NH1  1 ? 
ATOM   7847  N  NH2  . ARG A 1 513 ? -7.902  11.082  16.922  1   41.54   ? 519  ARG A NH2  1 ? 
ATOM   7848  H  H    . ARG A 1 513 ? -6.859  4.537   19.208  1   44.601  ? 519  ARG A H    1 c 
ATOM   7849  H  HA   . ARG A 1 513 ? -4.792  5.271   19.348  1   44.833  ? 519  ARG A HA   1 c 
ATOM   7850  H  HB2  . ARG A 1 513 ? -6.147  7.748   19.603  1   46.875  ? 519  ARG A HB2  1 c 
ATOM   7851  H  HB3  . ARG A 1 513 ? -4.571  7.668   19.408  1   46.862  ? 519  ARG A HB3  1 c 
ATOM   7852  H  HG2  . ARG A 1 513 ? -4.969  6.423   17.37   1   47.235  ? 519  ARG A HG2  1 c 
ATOM   7853  H  HG3  . ARG A 1 513 ? -6.504  6.709   17.543  1   47.274  ? 519  ARG A HG3  1 c 
ATOM   7854  H  HD2  . ARG A 1 513 ? -4.554  8.694   16.96   1   44.784  ? 519  ARG A HD2  1 c 
ATOM   7855  H  HD3  . ARG A 1 513 ? -5.628  8.142   15.934  1   44.79   ? 519  ARG A HD3  1 c 
ATOM   7856  H  HE   . ARG A 1 513 ? -6.707  9.36    18.129  1   43.06   ? 519  ARG A HE   1 c 
ATOM   7857  H  HH11 . ARG A 1 513 ? -5.419  10.487  15.264  1   46.009  ? 519  ARG A HH11 1 c 
ATOM   7858  H  HH12 . ARG A 1 513 ? -6.711  11.157  14.779  1   45.972  ? 519  ARG A HH12 1 c 
ATOM   7859  H  HH21 . ARG A 1 513 ? -8.362  10.832  17.635  1   42.348  ? 519  ARG A HH21 1 c 
ATOM   7860  H  HH22 . ARG A 1 513 ? -8.145  11.801  16.467  1   42.395  ? 519  ARG A HH22 1 c 
ATOM   7861  N  N    . PHE A 1 514 ? -4.807  4.559   21.845  1   46.036  ? 520  PHE A N    1 ? 
ATOM   7862  C  CA   . PHE A 1 514 ? -4.579  4.355   23.265  1   43.481  ? 520  PHE A CA   1 ? 
ATOM   7863  C  C    . PHE A 1 514 ? -3.419  3.385   23.45   1   36.376  ? 520  PHE A C    1 ? 
ATOM   7864  O  O    . PHE A 1 514 ? -3.361  2.343   22.823  1   39.738  ? 520  PHE A O    1 ? 
ATOM   7865  C  CB   . PHE A 1 514 ? -5.881  3.902   23.943  1   39.717  ? 520  PHE A CB   1 ? 
ATOM   7866  C  CG   . PHE A 1 514 ? -5.757  3.625   25.435  1   41.253  ? 520  PHE A CG   1 ? 
ATOM   7867  C  CD1  . PHE A 1 514 ? -5.939  4.637   26.366  1   40.634  ? 520  PHE A CD1  1 ? 
ATOM   7868  C  CD2  . PHE A 1 514 ? -5.361  2.369   25.891  1   46.55   ? 520  PHE A CD2  1 ? 
ATOM   7869  C  CE1  . PHE A 1 514 ? -5.775  4.384   27.72   1   45.564  ? 520  PHE A CE1  1 ? 
ATOM   7870  C  CE2  . PHE A 1 514 ? -5.217  2.123   27.241  1   40.918  ? 520  PHE A CE2  1 ? 
ATOM   7871  C  CZ   . PHE A 1 514 ? -5.434  3.124   28.151  1   41.084  ? 520  PHE A CZ   1 ? 
ATOM   7872  H  H    . PHE A 1 514 ? -4.89   3.829   21.302  1   44.549  ? 520  PHE A H    1 c 
ATOM   7873  H  HA   . PHE A 1 514 ? -4.319  5.225   23.661  1   41.777  ? 520  PHE A HA   1 c 
ATOM   7874  H  HB2  . PHE A 1 514 ? -6.561  4.597   23.806  1   40.922  ? 520  PHE A HB2  1 c 
ATOM   7875  H  HB3  . PHE A 1 514 ? -6.195  3.085   23.496  1   40.934  ? 520  PHE A HB3  1 c 
ATOM   7876  H  HD1  . PHE A 1 514 ? -6.184  5.501   26.076  1   41.889  ? 520  PHE A HD1  1 c 
ATOM   7877  H  HD2  . PHE A 1 514 ? -5.223  1.671   25.271  1   43.857  ? 520  PHE A HD2  1 c 
ATOM   7878  H  HE1  . PHE A 1 514 ? -5.93   5.071   28.349  1   43.275  ? 520  PHE A HE1  1 c 
ATOM   7879  H  HE2  . PHE A 1 514 ? -4.974  1.26    27.538  1   42.216  ? 520  PHE A HE2  1 c 
ATOM   7880  H  HZ   . PHE A 1 514 ? -5.326  2.954   29.073  1   42.067  ? 520  PHE A HZ   1 c 
ATOM   7881  N  N    . PHE A 1 515 ? -2.508  3.738   24.353  1   38.032  ? 521  PHE A N    1 ? 
ATOM   7882  C  CA   . PHE A 1 515 ? -1.476  2.809   24.786  1   37.603  ? 521  PHE A CA   1 ? 
ATOM   7883  C  C    . PHE A 1 515 ? -1.311  2.937   26.298  1   36.107  ? 521  PHE A C    1 ? 
ATOM   7884  O  O    . PHE A 1 515 ? -1.376  4.048   26.848  1   35.65   ? 521  PHE A O    1 ? 
ATOM   7885  C  CB   . PHE A 1 515 ? -0.201  3.143   23.995  1   39.846  ? 521  PHE A CB   1 ? 
ATOM   7886  C  CG   . PHE A 1 515 ? 1.021   2.399   24.479  1   34.106  ? 521  PHE A CG   1 ? 
ATOM   7887  C  CD1  . PHE A 1 515 ? 1.776   2.899   25.538  1   39.241  ? 521  PHE A CD1  1 ? 
ATOM   7888  C  CD2  . PHE A 1 515 ? 1.427   1.208   23.88   1   40.417  ? 521  PHE A CD2  1 ? 
ATOM   7889  C  CE1  . PHE A 1 515 ? 2.889   2.201   26.008  1   36.059  ? 521  PHE A CE1  1 ? 
ATOM   7890  C  CE2  . PHE A 1 515 ? 2.545   0.509   24.365  1   37.255  ? 521  PHE A CE2  1 ? 
ATOM   7891  C  CZ   . PHE A 1 515 ? 3.277   1.015   25.414  1   33.572  ? 521  PHE A CZ   1 ? 
ATOM   7892  H  H    . PHE A 1 515 ? -2.523  4.579   24.709  1   37.599  ? 521  PHE A H    1 c 
ATOM   7893  H  HA   . PHE A 1 515 ? -1.76   1.886   24.567  1   37.825  ? 521  PHE A HA   1 c 
ATOM   7894  H  HB2  . PHE A 1 515 ? -0.354  2.925   23.049  1   37.945  ? 521  PHE A HB2  1 c 
ATOM   7895  H  HB3  . PHE A 1 515 ? -0.034  4.109   24.063  1   37.945  ? 521  PHE A HB3  1 c 
ATOM   7896  H  HD1  . PHE A 1 515 ? 1.514   3.701   25.959  1   37.207  ? 521  PHE A HD1  1 c 
ATOM   7897  H  HD2  . PHE A 1 515 ? 0.924   0.849   23.167  1   38.102  ? 521  PHE A HD2  1 c 
ATOM   7898  H  HE1  . PHE A 1 515 ? 3.39    2.55    26.728  1   36.182  ? 521  PHE A HE1  1 c 
ATOM   7899  H  HE2  . PHE A 1 515 ? 2.811   -0.297  23.951  1   37.026  ? 521  PHE A HE2  1 c 
ATOM   7900  H  HZ   . PHE A 1 515 ? 4.039   0.554   25.728  1   35.049  ? 521  PHE A HZ   1 c 
ATOM   7901  N  N    . SER A 1 516 ? -1.091  1.802   26.977  1   36.629  ? 522  SER A N    1 ? 
ATOM   7902  C  CA   . SER A 1 516 ? -0.701  1.871   28.377  1   41.723  ? 522  SER A CA   1 ? 
ATOM   7903  C  C    . SER A 1 516 ? 0.207   0.702   28.749  1   45.415  ? 522  SER A C    1 ? 
ATOM   7904  O  O    . SER A 1 516 ? 0.229   -0.356  28.116  1   41.322  ? 522  SER A O    1 ? 
ATOM   7905  C  CB   . SER A 1 516 ? -1.88   1.988   29.329  1   42.866  ? 522  SER A CB   1 ? 
ATOM   7906  O  OG   . SER A 1 516 ? -2.74   0.859   29.265  1   42.743  ? 522  SER A OG   1 ? 
ATOM   7907  H  H    . SER A 1 516 ? -1.183  0.988   26.572  1   37.632  ? 522  SER A H    1 c 
ATOM   7908  H  HA   . SER A 1 516 ? -0.162  2.695   28.482  1   41.397  ? 522  SER A HA   1 c 
ATOM   7909  H  HB2  . SER A 1 516 ? -1.547  2.087   30.241  1   42.578  ? 522  SER A HB2  1 c 
ATOM   7910  H  HB3  . SER A 1 516 ? -2.39   2.79    29.108  1   42.582  ? 522  SER A HB3  1 c 
ATOM   7911  H  HG   . SER A 1 516 ? -3.386  0.928   29.809  0   42.93   ? 522  SER A HG   1 c 
ATOM   7912  N  N    . ALA A 1 517 ? 0.98    0.943   29.805  1   38      ? 523  ALA A N    1 ? 
ATOM   7913  C  CA   . ALA A 1 517 ? 1.903   -0.06   30.302  1   45.689  ? 523  ALA A CA   1 ? 
ATOM   7914  C  C    . ALA A 1 517 ? 2.049   0.114   31.805  1   44      ? 523  ALA A C    1 ? 
ATOM   7915  O  O    . ALA A 1 517 ? 2.233   1.241   32.279  1   38.813  ? 523  ALA A O    1 ? 
ATOM   7916  C  CB   . ALA A 1 517 ? 3.252   0.079   29.646  1   44.543  ? 523  ALA A CB   1 ? 
ATOM   7917  H  H    . ALA A 1 517 ? 0.932   1.751   30.229  1   41.353  ? 523  ALA A H    1 c 
ATOM   7918  H  HA   . ALA A 1 517 ? 1.529   -0.965  30.117  1   43.58   ? 523  ALA A HA   1 c 
ATOM   7919  H  HB1  . ALA A 1 517 ? 3.166   -0.062  28.688  1   44.88   ? 523  ALA A HB1  1 c 
ATOM   7920  H  HB2  . ALA A 1 517 ? 3.606   0.969   29.809  1   44.88   ? 523  ALA A HB2  1 c 
ATOM   7921  H  HB3  . ALA A 1 517 ? 3.863   -0.581  30.014  1   44.876  ? 523  ALA A HB3  1 c 
ATOM   7922  N  N    . ASN A 1 518 ? 2.018   -1.023  32.502  1   44.189  ? 524  ASN A N    1 ? 
ATOM   7923  C  CA   . ASN A 1 518 ? 2.422   -1.074  33.89   1   43.384  ? 524  ASN A CA   1 ? 
ATOM   7924  C  C    . ASN A 1 518 ? 3.938   -0.993  33.916  1   38.295  ? 524  ASN A C    1 ? 
ATOM   7925  O  O    . ASN A 1 518 ? 4.599   -1.962  33.596  1   40.915  ? 524  ASN A O    1 ? 
ATOM   7926  C  CB   . ASN A 1 518 ? 1.892   -2.338  34.55   1   46.941  ? 524  ASN A CB   1 ? 
ATOM   7927  C  CG   . ASN A 1 518 ? 2.07    -2.312  36.047  1   48.721  ? 524  ASN A CG   1 ? 
ATOM   7928  O  OD1  . ASN A 1 518 ? 2.897   -1.566  36.586  1   47.642  ? 524  ASN A OD1  1 ? 
ATOM   7929  N  ND2  . ASN A 1 518 ? 1.317   -3.16   36.724  1   57.577  ? 524  ASN A ND2  1 ? 
ATOM   7930  H  H    . ASN A 1 518 ? 1.734   -1.793  32.098  1   43.988  ? 524  ASN A H    1 c 
ATOM   7931  H  HA   . ASN A 1 518 ? 2.04    -0.301  34.361  1   43.125  ? 524  ASN A HA   1 c 
ATOM   7932  H  HB2  . ASN A 1 518 ? 0.941   -2.433  34.342  1   46.536  ? 524  ASN A HB2  1 c 
ATOM   7933  H  HB3  . ASN A 1 518 ? 2.36    -3.114  34.186  1   46.423  ? 524  ASN A HB3  1 c 
ATOM   7934  H  HD21 . ASN A 1 518 ? 1.404   -3.22   37.604  1   54.486  ? 524  ASN A HD21 1 c 
ATOM   7935  H  HD22 . ASN A 1 518 ? 0.727   -3.671  36.301  1   54.516  ? 524  ASN A HD22 1 c 
ATOM   7936  N  N    . ILE A 1 519 ? 4.467   0.173   34.286  1   40.347  ? 525  ILE A N    1 ? 
ATOM   7937  C  CA   . ILE A 1 519 ? 5.896   0.416   34.243  1   40.153  ? 525  ILE A CA   1 ? 
ATOM   7938  C  C    . ILE A 1 519 ? 6.562   0.141   35.595  1   41.229  ? 525  ILE A C    1 ? 
ATOM   7939  O  O    . ILE A 1 519 ? 7.778   0.266   35.698  1   37.352  ? 525  ILE A O    1 ? 
ATOM   7940  C  CB   . ILE A 1 519 ? 6.179   1.842   33.728  1   43.106  ? 525  ILE A CB   1 ? 
ATOM   7941  C  CG1  . ILE A 1 519 ? 5.677   2.925   34.67   1   46.078  ? 525  ILE A CG1  1 ? 
ATOM   7942  C  CG2  . ILE A 1 519 ? 5.625   2.026   32.312  1   41.926  ? 525  ILE A CG2  1 ? 
ATOM   7943  C  CD1  . ILE A 1 519 ? 6.216   4.298   34.31   1   40.403  ? 525  ILE A CD1  1 ? 
ATOM   7944  H  H    . ILE A 1 519 ? 3.916   0.839   34.581  1   39.922  ? 525  ILE A H    1 c 
ATOM   7945  H  HA   . ILE A 1 519 ? 6.281   -0.206  33.596  1   40.903  ? 525  ILE A HA   1 c 
ATOM   7946  H  HB   . ILE A 1 519 ? 7.151   1.939   33.673  1   42.826  ? 525  ILE A HB   1 c 
ATOM   7947  H  HG12 . ILE A 1 519 ? 4.699   2.949   34.638  1   43.958  ? 525  ILE A HG12 1 c 
ATOM   7948  H  HG13 . ILE A 1 519 ? 5.946   2.707   35.585  1   44.01   ? 525  ILE A HG13 1 c 
ATOM   7949  H  HG21 . ILE A 1 519 ? 5.952   2.862   31.94   1   42.194  ? 525  ILE A HG21 1 c 
ATOM   7950  H  HG22 . ILE A 1 519 ? 4.654   2.046   32.343  1   42.221  ? 525  ILE A HG22 1 c 
ATOM   7951  H  HG23 . ILE A 1 519 ? 5.915   1.288   31.75   1   42.245  ? 525  ILE A HG23 1 c 
ATOM   7952  H  HD11 . ILE A 1 519 ? 7.188   4.256   34.225  1   42.007  ? 525  ILE A HD11 1 c 
ATOM   7953  H  HD12 . ILE A 1 519 ? 5.981   4.933   35.012  1   42.004  ? 525  ILE A HD12 1 c 
ATOM   7954  H  HD13 . ILE A 1 519 ? 5.83    4.595   33.464  1   42.001  ? 525  ILE A HD13 1 c 
ATOM   7955  N  N    . ALA A 1 520 ? 5.777   -0.274  36.613  1   40.892  ? 526  ALA A N    1 ? 
ATOM   7956  C  CA   . ALA A 1 520 ? 6.271   -0.523  37.954  1   36.936  ? 526  ALA A CA   1 ? 
ATOM   7957  C  C    . ALA A 1 520 ? 7.471   -1.468  37.912  1   40.159  ? 526  ALA A C    1 ? 
ATOM   7958  O  O    . ALA A 1 520 ? 8.432   -1.303  38.677  1   40.576  ? 526  ALA A O    1 ? 
ATOM   7959  C  CB   . ALA A 1 520 ? 5.158   -1.1    38.831  1   37.463  ? 526  ALA A CB   1 ? 
ATOM   7960  H  H    . ALA A 1 520 ? 4.887   -0.403  36.454  1   40.009  ? 526  ALA A H    1 c 
ATOM   7961  H  HA   . ALA A 1 520 ? 6.573   0.346   38.34   1   38.359  ? 526  ALA A HA   1 c 
ATOM   7962  H  HB1  . ALA A 1 520 ? 4.453   -0.441  38.936  1   37.372  ? 526  ALA A HB1  1 c 
ATOM   7963  H  HB2  . ALA A 1 520 ? 4.793   -1.899  38.414  1   37.37   ? 526  ALA A HB2  1 c 
ATOM   7964  H  HB3  . ALA A 1 520 ? 5.516   -1.329  39.705  1   37.332  ? 526  ALA A HB3  1 c 
ATOM   7965  N  N    . THR A 1 521 ? 7.415   -2.422  36.975  1   42.679  ? 527  THR A N    1 ? 
ATOM   7966  C  CA   . THR A 1 521 ? 8.345   -3.538  36.924  1   42.048  ? 527  THR A CA   1 ? 
ATOM   7967  C  C    . THR A 1 521 ? 9.635   -3.171  36.215  1   42.919  ? 527  THR A C    1 ? 
ATOM   7968  O  O    . THR A 1 521 ? 10.503  -4.042  36.111  1   47.717  ? 527  THR A O    1 ? 
ATOM   7969  C  CB   . THR A 1 521 ? 7.669   -4.737  36.258  1   48.13   ? 527  THR A CB   1 ? 
ATOM   7970  O  OG1  . THR A 1 521 ? 6.834   -4.223  35.217  1   49.264  ? 527  THR A OG1  1 ? 
ATOM   7971  C  CG2  . THR A 1 521 ? 6.807   -5.517  37.241  1   45.955  ? 527  THR A CG2  1 ? 
ATOM   7972  H  H    . THR A 1 521 ? 6.754   -2.385  36.345  1   41.914  ? 527  THR A H    1 c 
ATOM   7973  H  HA   . THR A 1 521 ? 8.565   -3.789  37.848  1   43.394  ? 527  THR A HA   1 c 
ATOM   7974  H  HB   . THR A 1 521 ? 8.345   -5.341  35.869  1   46.774  ? 527  THR A HB   1 c 
ATOM   7975  H  HG1  . THR A 1 521 ? 6.26    -3.679  35.58   0   48.87   ? 527  THR A HG1  1 c 
ATOM   7976  H  HG21 . THR A 1 521 ? 6.395   -6.27   36.785  1   46.58   ? 527  THR A HG21 1 c 
ATOM   7977  H  HG22 . THR A 1 521 ? 6.114   -4.936  37.597  1   46.58   ? 527  THR A HG22 1 c 
ATOM   7978  H  HG23 . THR A 1 521 ? 7.36    -5.844  37.97   1   46.563  ? 527  THR A HG23 1 c 
ATOM   7979  N  N    . ALA A 1 522 ? 9.771   -1.906  35.78   1   40.619  ? 528  ALA A N    1 ? 
ATOM   7980  C  CA   . ALA A 1 522 ? 11.038  -1.388  35.273  1   46.734  ? 528  ALA A CA   1 ? 
ATOM   7981  C  C    . ALA A 1 522 ? 11.797  -0.643  36.371  1   45.583  ? 528  ALA A C    1 ? 
ATOM   7982  O  O    . ALA A 1 522 ? 12.891  -0.127  36.128  1   42.802  ? 528  ALA A O    1 ? 
ATOM   7983  C  CB   . ALA A 1 522 ? 10.806  -0.472  34.079  1   51.846  ? 528  ALA A CB   1 ? 
ATOM   7984  H  H    . ALA A 1 522 ? 9.045   -1.352  35.777  1   42.505  ? 528  ALA A H    1 c 
ATOM   7985  H  HA   . ALA A 1 522 ? 11.595  -2.159  34.981  1   46.137  ? 528  ALA A HA   1 c 
ATOM   7986  H  HB1  . ALA A 1 522 ? 10.349  -0.962  33.375  1   50.274  ? 528  ALA A HB1  1 c 
ATOM   7987  H  HB2  . ALA A 1 522 ? 10.259  0.285   34.349  1   50.274  ? 528  ALA A HB2  1 c 
ATOM   7988  H  HB3  . ALA A 1 522 ? 11.659  -0.149  33.743  1   50.241  ? 528  ALA A HB3  1 c 
ATOM   7989  N  N    . TYR A 1 523 ? 11.19   -0.545  37.562  1   39.965  ? 529  TYR A N    1 ? 
ATOM   7990  C  CA   . TYR A 1 523 ? 11.841  0.074   38.703  1   42.722  ? 529  TYR A CA   1 ? 
ATOM   7991  C  C    . TYR A 1 523 ? 12.336  -0.992  39.683  1   42.044  ? 529  TYR A C    1 ? 
ATOM   7992  O  O    . TYR A 1 523 ? 11.817  -2.1    39.773  1   43.075  ? 529  TYR A O    1 ? 
ATOM   7993  C  CB   . TYR A 1 523 ? 10.916  1.089   39.373  1   42.804  ? 529  TYR A CB   1 ? 
ATOM   7994  C  CG   . TYR A 1 523 ? 10.512  2.255   38.475  1   40.674  ? 529  TYR A CG   1 ? 
ATOM   7995  C  CD1  . TYR A 1 523 ? 9.595   2.087   37.443  1   40.216  ? 529  TYR A CD1  1 ? 
ATOM   7996  C  CD2  . TYR A 1 523 ? 11.004  3.528   38.691  1   35.869  ? 529  TYR A CD2  1 ? 
ATOM   7997  C  CE1  . TYR A 1 523 ? 9.218   3.143   36.627  1   39.325  ? 529  TYR A CE1  1 ? 
ATOM   7998  C  CE2  . TYR A 1 523 ? 10.637  4.593   37.882  1   41.884  ? 529  TYR A CE2  1 ? 
ATOM   7999  C  CZ   . TYR A 1 523 ? 9.743   4.396   36.844  1   38.214  ? 529  TYR A CZ   1 ? 
ATOM   8000  O  OH   . TYR A 1 523 ? 9.378   5.422   36.036  1   42.211  ? 529  TYR A OH   1 ? 
ATOM   8001  H  H    . TYR A 1 523 ? 10.342  -0.867  37.666  1   41.886  ? 529  TYR A H    1 c 
ATOM   8002  H  HA   . TYR A 1 523 ? 12.633  0.568   38.367  1   42.12   ? 529  TYR A HA   1 c 
ATOM   8003  H  HB2  . TYR A 1 523 ? 10.104  0.622   39.671  1   42.282  ? 529  TYR A HB2  1 c 
ATOM   8004  H  HB3  . TYR A 1 523 ? 11.367  1.444   40.171  1   42.241  ? 529  TYR A HB3  1 c 
ATOM   8005  H  HD1  . TYR A 1 523 ? 9.238   1.23    37.28   1   40.077  ? 529  TYR A HD1  1 c 
ATOM   8006  H  HD2  . TYR A 1 523 ? 11.624  3.671   39.388  1   38.379  ? 529  TYR A HD2  1 c 
ATOM   8007  H  HE1  . TYR A 1 523 ? 8.611   3.002   35.921  1   39.301  ? 529  TYR A HE1  1 c 
ATOM   8008  H  HE2  . TYR A 1 523 ? 11.002  5.449   38.034  1   39.576  ? 529  TYR A HE2  1 c 
ATOM   8009  H  HH   . TYR A 1 523 ? 8.693   5.826   36.379  0   42.33   ? 529  TYR A HH   1 c 
ATOM   8010  N  N    . PRO A 1 524 ? 13.402  -0.704  40.44   1   39.621  ? 530  PRO A N    1 ? 
ATOM   8011  C  CA   . PRO A 1 524 ? 13.897  -1.642  41.438  1   45.064  ? 530  PRO A CA   1 ? 
ATOM   8012  C  C    . PRO A 1 524 ? 13.065  -1.598  42.717  1   46.393  ? 530  PRO A C    1 ? 
ATOM   8013  O  O    . PRO A 1 524 ? 12.185  -0.743  42.886  1   48.56   ? 530  PRO A O    1 ? 
ATOM   8014  C  CB   . PRO A 1 524 ? 15.317  -1.115  41.633  1   45.248  ? 530  PRO A CB   1 ? 
ATOM   8015  C  CG   . PRO A 1 524 ? 15.115  0.378   41.573  1   45.02   ? 530  PRO A CG   1 ? 
ATOM   8016  C  CD   . PRO A 1 524 ? 14.194  0.525   40.366  1   46.045  ? 530  PRO A CD   1 ? 
ATOM   8017  H  HA   . PRO A 1 524 ? 13.918  -2.557  41.067  1   44.316  ? 530  PRO A HA   1 c 
ATOM   8018  H  HB2  . PRO A 1 524 ? 15.682  -1.392  42.505  1   45.257  ? 530  PRO A HB2  1 c 
ATOM   8019  H  HB3  . PRO A 1 524 ? 15.913  -1.424  40.911  1   45.175  ? 530  PRO A HB3  1 c 
ATOM   8020  H  HG2  . PRO A 1 524 ? 14.69   0.715   42.389  1   45.312  ? 530  PRO A HG2  1 c 
ATOM   8021  H  HG3  . PRO A 1 524 ? 15.964  0.846   41.432  1   45.343  ? 530  PRO A HG3  1 c 
ATOM   8022  H  HD2  . PRO A 1 524 ? 13.627  1.323   40.448  1   44.223  ? 530  PRO A HD2  1 c 
ATOM   8023  H  HD3  . PRO A 1 524 ? 14.707  0.571   39.53   1   44.275  ? 530  PRO A HD3  1 c 
ATOM   8024  N  N    . LYS A 1 525 ? 13.379  -2.515  43.626  1   49.101  ? 531  LYS A N    1 ? 
ATOM   8025  C  CA   . LYS A 1 525 ? 12.651  -2.684  44.882  1   49.174  ? 531  LYS A CA   1 ? 
ATOM   8026  C  C    . LYS A 1 525 ? 12.662  -1.414  45.714  1   45.108  ? 531  LYS A C    1 ? 
ATOM   8027  O  O    . LYS A 1 525 ? 11.695  -1.119  46.399  1   53.874  ? 531  LYS A O    1 ? 
ATOM   8028  C  CB   . LYS A 1 525 ? 13.314  -3.816  45.669  1   62.302  ? 531  LYS A CB   1 ? 
ATOM   8029  C  CG   . LYS A 1 525 ? 13.135  -5.183  45.002  1   82.001  ? 531  LYS A CG   1 ? 
ATOM   8030  C  CD   . LYS A 1 525 ? 13.673  -6.387  45.773  1   98.818  ? 531  LYS A CD   1 ? 
ATOM   8031  C  CE   . LYS A 1 525 ? 13.584  -7.686  45.017  1   101.136 ? 531  LYS A CE   1 ? 
ATOM   8032  N  NZ   . LYS A 1 525 ? 14.056  -8.814  45.831  1   99.291  ? 531  LYS A NZ   1 ? 
ATOM   8033  H  H    . LYS A 1 525 ? 14.093  -3.062  43.461  1   48.967  ? 531  LYS A H    1 c 
ATOM   8034  H  HA   . LYS A 1 525 ? 11.713  -2.927  44.674  1   50.513  ? 531  LYS A HA   1 c 
ATOM   8035  H  HB2  . LYS A 1 525 ? 14.273  -3.631  45.757  1   62.742  ? 531  LYS A HB2  1 c 
ATOM   8036  H  HB3  . LYS A 1 525 ? 12.928  -3.852  46.57   1   62.733  ? 531  LYS A HB3  1 c 
ATOM   8037  H  HG2  . LYS A 1 525 ? 12.175  -5.32   44.842  1   80.224  ? 531  LYS A HG2  1 c 
ATOM   8038  H  HG3  . LYS A 1 525 ? 13.573  -5.156  44.125  1   79.73   ? 531  LYS A HG3  1 c 
ATOM   8039  H  HD2  . LYS A 1 525 ? 14.612  -6.219  46.005  1   95.225  ? 531  LYS A HD2  1 c 
ATOM   8040  H  HD3  . LYS A 1 525 ? 13.17   -6.473  46.612  1   95.224  ? 531  LYS A HD3  1 c 
ATOM   8041  H  HE2  . LYS A 1 525 ? 12.66   -7.848  44.755  1   99.891  ? 531  LYS A HE2  1 c 
ATOM   8042  H  HE3  . LYS A 1 525 ? 14.124  -7.631  44.208  1   100.115 ? 531  LYS A HE3  1 c 
ATOM   8043  H  HZ1  . LYS A 1 525 ? 13.533  -8.899  46.567  1   99.855  ? 531  LYS A HZ1  1 c 
ATOM   8044  H  HZ2  . LYS A 1 525 ? 14.912  -8.668  46.09   1   99.855  ? 531  LYS A HZ2  1 c 
ATOM   8045  H  HZ3  . LYS A 1 525 ? 14.016  -9.579  45.348  1   99.855  ? 531  LYS A HZ3  1 c 
ATOM   8046  N  N    . GLU A 1 526 ? 13.736  -0.631  45.623  1   52.951  ? 532  GLU A N    1 ? 
ATOM   8047  C  CA   . GLU A 1 526 ? 13.84   0.614   46.37   1   53.163  ? 532  GLU A CA   1 ? 
ATOM   8048  C  C    . GLU A 1 526 ? 12.727  1.6     45.988  1   50.289  ? 532  GLU A C    1 ? 
ATOM   8049  O  O    . GLU A 1 526 ? 12.473  2.549   46.722  1   60.433  ? 532  GLU A O    1 ? 
ATOM   8050  C  CB   . GLU A 1 526 ? 15.205  1.276   46.146  1   60.921  ? 532  GLU A CB   1 ? 
ATOM   8051  C  CG   . GLU A 1 526 ? 16.391  0.529   46.743  1   64.113  ? 532  GLU A CG   1 ? 
ATOM   8052  C  CD   . GLU A 1 526 ? 16.879  -0.698  45.988  1   69.306  ? 532  GLU A CD   1 ? 
ATOM   8053  O  OE1  . GLU A 1 526 ? 17.254  -1.654  46.694  1   72.639  ? 532  GLU A OE1  1 ? 
ATOM   8054  O  OE2  . GLU A 1 526 ? 16.902  -0.72   44.732  1   66.284  ? 532  GLU A OE2  1 ? 
ATOM   8055  H  H    . GLU A 1 526 ? 14.426  -0.876  45.078  1   51.115  ? 532  GLU A H    1 c 
ATOM   8056  H  HA   . GLU A 1 526 ? 13.751  0.401   47.334  1   53.912  ? 532  GLU A HA   1 c 
ATOM   8057  H  HB2  . GLU A 1 526 ? 15.35   1.373   45.182  1   59.78   ? 532  GLU A HB2  1 c 
ATOM   8058  H  HB3  . GLU A 1 526 ? 15.182  2.176   46.533  1   59.711  ? 532  GLU A HB3  1 c 
ATOM   8059  H  HG2  . GLU A 1 526 ? 17.143  1.154   46.822  1   64.525  ? 532  GLU A HG2  1 c 
ATOM   8060  H  HG3  . GLU A 1 526 ? 16.156  0.252   47.654  1   64.563  ? 532  GLU A HG3  1 c 
ATOM   8061  N  N    . ALA A 1 527 ? 12.07   1.414   44.838  1   50.007  ? 533  ALA A N    1 ? 
ATOM   8062  C  CA   . ALA A 1 527 ? 10.945  2.265   44.463  1   51.512  ? 533  ALA A CA   1 ? 
ATOM   8063  C  C    . ALA A 1 527 ? 9.674   1.92    45.254  1   48.944  ? 533  ALA A C    1 ? 
ATOM   8064  O  O    . ALA A 1 527 ? 8.78    2.751   45.342  1   47.21   ? 533  ALA A O    1 ? 
ATOM   8065  C  CB   . ALA A 1 527 ? 10.689  2.161   42.98   1   46.421  ? 533  ALA A CB   1 ? 
ATOM   8066  H  H    . ALA A 1 527 ? 12.338  0.758   44.261  1   50.361  ? 533  ALA A H    1 c 
ATOM   8067  H  HA   . ALA A 1 527 ? 11.19   3.208   44.675  1   49.832  ? 533  ALA A HA   1 c 
ATOM   8068  H  HB1  . ALA A 1 527 ? 11.494  2.403   42.492  1   47.876  ? 533  ALA A HB1  1 c 
ATOM   8069  H  HB2  . ALA A 1 527 ? 10.439  1.249   42.755  1   47.866  ? 533  ALA A HB2  1 c 
ATOM   8070  H  HB3  . ALA A 1 527 ? 9.968   2.763   42.73   1   47.876  ? 533  ALA A HB3  1 c 
ATOM   8071  N  N    . GLU A 1 528 ? 9.569   0.69    45.779  1   49.799  ? 534  GLU A N    1 ? 
ATOM   8072  C  CA   . GLU A 1 528 ? 8.535   0.331   46.745  1   48.975  ? 534  GLU A CA   1 ? 
ATOM   8073  C  C    . GLU A 1 528 ? 7.169   0.554   46.122  1   42.942  ? 534  GLU A C    1 ? 
ATOM   8074  O  O    . GLU A 1 528 ? 6.322   1.247   46.69   1   46.492  ? 534  GLU A O    1 ? 
ATOM   8075  C  CB   . GLU A 1 528 ? 8.559   1.183   48.016  1   49.745  ? 534  GLU A CB   1 ? 
ATOM   8076  C  CG   . GLU A 1 528 ? 9.929   1.24    48.682  1   59.953  ? 534  GLU A CG   1 ? 
ATOM   8077  C  CD   . GLU A 1 528 ? 10.155  0.492   49.974  1   65.694  ? 534  GLU A CD   1 ? 
ATOM   8078  O  OE1  . GLU A 1 528 ? 11.333  0.534   50.37   1   79.61   ? 534  GLU A OE1  1 ? 
ATOM   8079  O  OE2  . GLU A 1 528 ? 9.235   -0.108  50.573  1   82.297  ? 534  GLU A OE2  1 ? 
ATOM   8080  H  H    . GLU A 1 528 ? 10.161  0.044   45.518  1   49.403  ? 534  GLU A H    1 c 
ATOM   8081  H  HA   . GLU A 1 528 ? 8.634   -0.626  46.979  1   48.096  ? 534  GLU A HA   1 c 
ATOM   8082  H  HB2  . GLU A 1 528 ? 8.288   2.098   47.795  1   51.613  ? 534  GLU A HB2  1 c 
ATOM   8083  H  HB3  . GLU A 1 528 ? 7.905   0.824   48.651  1   51.824  ? 534  GLU A HB3  1 c 
ATOM   8084  H  HG2  . GLU A 1 528 ? 10.596  0.921   48.038  1   58.585  ? 534  GLU A HG2  1 c 
ATOM   8085  H  HG3  . GLU A 1 528 ? 10.141  2.178   48.848  1   58.737  ? 534  GLU A HG3  1 c 
ATOM   8086  N  N    . VAL A 1 529 ? 6.996   -0.004  44.923  1   42.546  ? 535  VAL A N    1 ? 
ATOM   8087  C  CA   . VAL A 1 529 ? 5.814   0.265   44.129  1   44.764  ? 535  VAL A CA   1 ? 
ATOM   8088  C  C    . VAL A 1 529 ? 5.139   -1.068  43.862  1   45.997  ? 535  VAL A C    1 ? 
ATOM   8089  O  O    . VAL A 1 529 ? 5.819   -2.066  43.66   1   45.184  ? 535  VAL A O    1 ? 
ATOM   8090  C  CB   . VAL A 1 529 ? 6.192   1.018   42.834  1   44.249  ? 535  VAL A CB   1 ? 
ATOM   8091  C  CG1  . VAL A 1 529 ? 7.384   0.385   42.121  1   45.929  ? 535  VAL A CG1  1 ? 
ATOM   8092  C  CG2  . VAL A 1 529 ? 5.008   1.167   41.888  1   45.61   ? 535  VAL A CG2  1 ? 
ATOM   8093  H  H    . VAL A 1 529 ? 7.623   -0.585  44.602  1   43.258  ? 535  VAL A H    1 c 
ATOM   8094  H  HA   . VAL A 1 529 ? 5.207   0.824   44.648  1   44.509  ? 535  VAL A HA   1 c 
ATOM   8095  H  HB   . VAL A 1 529 ? 6.465   1.927   43.103  1   44.908  ? 535  VAL A HB   1 c 
ATOM   8096  H  HG11 . VAL A 1 529 ? 7.237   -0.571  42.025  1   45.428  ? 535  VAL A HG11 1 c 
ATOM   8097  H  HG12 . VAL A 1 529 ? 8.192   0.538   42.638  1   45.42   ? 535  VAL A HG12 1 c 
ATOM   8098  H  HG13 . VAL A 1 529 ? 7.484   0.785   41.241  1   45.427  ? 535  VAL A HG13 1 c 
ATOM   8099  H  HG21 . VAL A 1 529 ? 5.252   1.753   41.152  1   45.205  ? 535  VAL A HG21 1 c 
ATOM   8100  H  HG22 . VAL A 1 529 ? 4.254   1.548   42.368  1   45.206  ? 535  VAL A HG22 1 c 
ATOM   8101  H  HG23 . VAL A 1 529 ? 4.759   0.295   41.536  1   45.209  ? 535  VAL A HG23 1 c 
ATOM   8102  N  N    . ASN A 1 530 ? 3.804   -1.084  43.921  1   51.263  ? 536  ASN A N    1 ? 
ATOM   8103  C  CA   . ASN A 1 530 ? 3.052   -2.282  43.597  1   41.632  ? 536  ASN A CA   1 ? 
ATOM   8104  C  C    . ASN A 1 530 ? 2.721   -2.273  42.113  1   42.703  ? 536  ASN A C    1 ? 
ATOM   8105  O  O    . ASN A 1 530 ? 2.907   -3.273  41.434  1   42.119  ? 536  ASN A O    1 ? 
ATOM   8106  C  CB   . ASN A 1 530 ? 1.771   -2.379  44.407  1   48.604  ? 536  ASN A CB   1 ? 
ATOM   8107  C  CG   . ASN A 1 530 ? 2.051   -2.669  45.861  1   49.233  ? 536  ASN A CG   1 ? 
ATOM   8108  O  OD1  . ASN A 1 530 ? 2.855   -3.556  46.186  1   46.197  ? 536  ASN A OD1  1 ? 
ATOM   8109  N  ND2  . ASN A 1 530 ? 1.411   -1.91   46.732  1   46.61   ? 536  ASN A ND2  1 ? 
ATOM   8110  H  H    . ASN A 1 530 ? 3.351   -0.331  44.17   1   47.595  ? 536  ASN A H    1 c 
ATOM   8111  H  HA   . ASN A 1 530 ? 3.602   -3.072  43.8    1   44.859  ? 536  ASN A HA   1 c 
ATOM   8112  H  HB2  . ASN A 1 530 ? 1.279   -1.538  44.332  1   47.026  ? 536  ASN A HB2  1 c 
ATOM   8113  H  HB3  . ASN A 1 530 ? 1.211   -3.092  44.039  1   47.027  ? 536  ASN A HB3  1 c 
ATOM   8114  H  HD21 . ASN A 1 530 ? 1.614   -1.964  47.594  1   47.394  ? 536  ASN A HD21 1 c 
ATOM   8115  H  HD22 . ASN A 1 530 ? 0.779   -1.348  46.461  1   47.405  ? 536  ASN A HD22 1 c 
ATOM   8116  N  N    . SER A 1 531 ? 2.161   -1.154  41.647  1   43.868  ? 537  SER A N    1 ? 
ATOM   8117  C  CA   . SER A 1 531 ? 1.825   -0.985  40.244  1   47.406  ? 537  SER A CA   1 ? 
ATOM   8118  C  C    . SER A 1 531 ? 1.77    0.495   39.895  1   40.38   ? 537  SER A C    1 ? 
ATOM   8119  O  O    . SER A 1 531 ? 1.468   1.361   40.717  1   39.561  ? 537  SER A O    1 ? 
ATOM   8120  C  CB   . SER A 1 531 ? 0.547   -1.689  39.86   1   45.146  ? 537  SER A CB   1 ? 
ATOM   8121  O  OG   . SER A 1 531 ? -0.5    -1.194  40.661  1   53.691  ? 537  SER A OG   1 ? 
ATOM   8122  H  H    . SER A 1 531 ? 1.974   -0.473  42.228  1   44.377  ? 537  SER A H    1 c 
ATOM   8123  H  HA   . SER A 1 531 ? 2.557   -1.389  39.715  1   44.703  ? 537  SER A HA   1 c 
ATOM   8124  H  HB2  . SER A 1 531 ? 0.351   -1.525  38.918  1   47.615  ? 537  SER A HB2  1 c 
ATOM   8125  H  HB3  . SER A 1 531 ? 0.646   -2.65   40      1   47.582  ? 537  SER A HB3  1 c 
ATOM   8126  H  HG   . SER A 1 531 ? -1.221  -1.603  40.372  0   52.39   ? 537  SER A HG   1 c 
ATOM   8127  N  N    . TRP A 1 532 ? 2.123   0.767   38.645  1   36.848  ? 538  TRP A N    1 ? 
ATOM   8128  C  CA   . TRP A 1 532 ? 2.137   2.122   38.139  1   37.69   ? 538  TRP A CA   1 ? 
ATOM   8129  C  C    . TRP A 1 532 ? 1.883   2.052   36.643  1   37.843  ? 538  TRP A C    1 ? 
ATOM   8130  O  O    . TRP A 1 532 ? 2.736   1.564   35.901  1   35.297  ? 538  TRP A O    1 ? 
ATOM   8131  C  CB   . TRP A 1 532 ? 3.465   2.809   38.487  1   38.697  ? 538  TRP A CB   1 ? 
ATOM   8132  C  CG   . TRP A 1 532 ? 3.493   4.251   38.068  1   40.511  ? 538  TRP A CG   1 ? 
ATOM   8133  C  CD1  . TRP A 1 532 ? 3.243   4.751   36.82   1   41.14   ? 538  TRP A CD1  1 ? 
ATOM   8134  C  CD2  . TRP A 1 532 ? 3.716   5.393   38.922  1   38.144  ? 538  TRP A CD2  1 ? 
ATOM   8135  N  NE1  . TRP A 1 532 ? 3.288   6.119   36.832  1   35.584  ? 538  TRP A NE1  1 ? 
ATOM   8136  C  CE2  . TRP A 1 532 ? 3.594   6.544   38.102  1   39.058  ? 538  TRP A CE2  1 ? 
ATOM   8137  C  CE3  . TRP A 1 532 ? 4.004   5.551   40.282  1   35.929  ? 538  TRP A CE3  1 ? 
ATOM   8138  C  CZ2  . TRP A 1 532 ? 3.741   7.831   38.612  1   32.187  ? 538  TRP A CZ2  1 ? 
ATOM   8139  C  CZ3  . TRP A 1 532 ? 4.186   6.82    40.776  1   34.018  ? 538  TRP A CZ3  1 ? 
ATOM   8140  C  CH2  . TRP A 1 532 ? 4.046   7.94    39.95   1   36.126  ? 538  TRP A CH2  1 ? 
ATOM   8141  H  H    . TRP A 1 532 ? 2.359   0.085   38.085  1   37.964  ? 538  TRP A H    1 c 
ATOM   8142  H  HA   . TRP A 1 532 ? 1.397   2.63    38.568  1   37.82   ? 538  TRP A HA   1 c 
ATOM   8143  H  HB2  . TRP A 1 532 ? 3.603   2.755   39.457  1   38.879  ? 538  TRP A HB2  1 c 
ATOM   8144  H  HB3  . TRP A 1 532 ? 4.194   2.331   38.039  1   38.859  ? 538  TRP A HB3  1 c 
ATOM   8145  H  HD1  . TRP A 1 532 ? 3.05    4.237   36.054  1   39.556  ? 538  TRP A HD1  1 c 
ATOM   8146  H  HE1  . TRP A 1 532 ? 3.18    6.631   36.135  1   37.627  ? 538  TRP A HE1  1 c 
ATOM   8147  H  HE3  . TRP A 1 532 ? 4.109   4.799   40.839  1   35.969  ? 538  TRP A HE3  1 c 
ATOM   8148  H  HZ2  . TRP A 1 532 ? 3.659   8.591   38.06   1   34.594  ? 538  TRP A HZ2  1 c 
ATOM   8149  H  HZ3  . TRP A 1 532 ? 4.38    6.94    41.691  1   34.967  ? 538  TRP A HZ3  1 c 
ATOM   8150  H  HH2  . TRP A 1 532 ? 4.158   8.797   40.322  1   34.72   ? 538  TRP A HH2  1 c 
ATOM   8151  N  N    . THR A 1 533 ? 0.648   2.417   36.259  1   44.746  ? 539  THR A N    1 ? 
ATOM   8152  C  CA   . THR A 1 533 ? 0.193   2.398   34.878  1   37.77   ? 539  THR A CA   1 ? 
ATOM   8153  C  C    . THR A 1 533 ? 0.334   3.809   34.31   1   40.862  ? 539  THR A C    1 ? 
ATOM   8154  O  O    . THR A 1 533 ? -0.322  4.759   34.771  1   37.603  ? 539  THR A O    1 ? 
ATOM   8155  C  CB   . THR A 1 533 ? -1.256  1.934   34.781  1   39.47   ? 539  THR A CB   1 ? 
ATOM   8156  O  OG1  . THR A 1 533 ? -1.256  0.558   35.153  1   38.383  ? 539  THR A OG1  1 ? 
ATOM   8157  C  CG2  . THR A 1 533 ? -1.791  2.064   33.362  1   41.262  ? 539  THR A CG2  1 ? 
ATOM   8158  H  H    . THR A 1 533 ? 0.057   2.691   36.9    1   41.313  ? 539  THR A H    1 c 
ATOM   8159  H  HA   . THR A 1 533 ? 0.757   1.781   34.366  1   39.878  ? 539  THR A HA   1 c 
ATOM   8160  H  HB   . THR A 1 533 ? -1.823  2.448   35.405  1   39.259  ? 539  THR A HB   1 c 
ATOM   8161  H  HG1  . THR A 1 533 ? -0.727  0.118   34.606  0   38.42   ? 539  THR A HG1  1 c 
ATOM   8162  H  HG21 . THR A 1 533 ? -2.645  1.602   33.294  1   40.726  ? 539  THR A HG21 1 c 
ATOM   8163  H  HG22 . THR A 1 533 ? -1.159  1.667   32.739  1   40.726  ? 539  THR A HG22 1 c 
ATOM   8164  H  HG23 . THR A 1 533 ? -1.915  3.003   33.143  1   40.727  ? 539  THR A HG23 1 c 
ATOM   8165  N  N    . ARG A 1 534 ? 1.163   3.892   33.265  1   39.456  ? 540  ARG A N    1 ? 
ATOM   8166  C  CA   . ARG A 1 534 ? 1.314   5.088   32.454  1   39.332  ? 540  ARG A CA   1 ? 
ATOM   8167  C  C    . ARG A 1 534 ? 0.54    4.873   31.157  1   38.683  ? 540  ARG A C    1 ? 
ATOM   8168  O  O    . ARG A 1 534 ? 0.79    3.91    30.443  1   33.932  ? 540  ARG A O    1 ? 
ATOM   8169  C  CB   . ARG A 1 534 ? 2.801   5.318   32.143  1   39.52   ? 540  ARG A CB   1 ? 
ATOM   8170  C  CG   . ARG A 1 534 ? 3.129   6.456   31.174  1   37.708  ? 540  ARG A CG   1 ? 
ATOM   8171  C  CD   . ARG A 1 534 ? 2.673   7.805   31.726  1   36.374  ? 540  ARG A CD   1 ? 
ATOM   8172  N  NE   . ARG A 1 534 ? 3.595   8.795   31.199  1   53.597  ? 540  ARG A NE   1 ? 
ATOM   8173  C  CZ   . ARG A 1 534 ? 4.345   9.639   31.853  1   50.825  ? 540  ARG A CZ   1 ? 
ATOM   8174  N  NH1  . ARG A 1 534 ? 4.228   9.797   33.146  1   39.836  ? 540  ARG A NH1  1 ? 
ATOM   8175  N  NH2  . ARG A 1 534 ? 5.173   10.376  31.156  1   63.164  ? 540  ARG A NH2  1 ? 
ATOM   8176  H  H    . ARG A 1 534 ? 1.667   3.161   33.048  1   39.738  ? 540  ARG A H    1 c 
ATOM   8177  H  HA   . ARG A 1 534 ? 0.943   5.863   32.944  1   39.273  ? 540  ARG A HA   1 c 
ATOM   8178  H  HB2  . ARG A 1 534 ? 3.265   5.491   32.989  1   39.065  ? 540  ARG A HB2  1 c 
ATOM   8179  H  HB3  . ARG A 1 534 ? 3.167   4.486   31.775  1   39.062  ? 540  ARG A HB3  1 c 
ATOM   8180  H  HG2  . ARG A 1 534 ? 4.099   6.481   31.021  1   37.889  ? 540  ARG A HG2  1 c 
ATOM   8181  H  HG3  . ARG A 1 534 ? 2.688   6.293   30.312  1   37.821  ? 540  ARG A HG3  1 c 
ATOM   8182  H  HD2  . ARG A 1 534 ? 1.762   8.01    31.433  1   40.25   ? 540  ARG A HD2  1 c 
ATOM   8183  H  HD3  . ARG A 1 534 ? 2.701   7.803   32.7    1   40.256  ? 540  ARG A HD3  1 c 
ATOM   8184  H  HE   . ARG A 1 534 ? 3.654   8.835   30.334  1   48.175  ? 540  ARG A HE   1 c 
ATOM   8185  H  HH11 . ARG A 1 534 ? 3.557   9.434   33.581  1   42.954  ? 540  ARG A HH11 1 c 
ATOM   8186  H  HH12 . ARG A 1 534 ? 4.83    10.278  33.583  1   43.178  ? 540  ARG A HH12 1 c 
ATOM   8187  H  HH21 . ARG A 1 534 ? 5.265   10.246  30.286  1   58.829  ? 540  ARG A HH21 1 c 
ATOM   8188  H  HH22 . ARG A 1 534 ? 5.642   11.008  31.559  1   58.694  ? 540  ARG A HH22 1 c 
ATOM   8189  N  N    . ALA A 1 535 ? -0.366  5.805   30.835  1   40.985  ? 541  ALA A N    1 ? 
ATOM   8190  C  CA   . ALA A 1 535 ? -1.311  5.626   29.739  1   42.036  ? 541  ALA A CA   1 ? 
ATOM   8191  C  C    . ALA A 1 535 ? -1.347  6.881   28.855  1   38.613  ? 541  ALA A C    1 ? 
ATOM   8192  O  O    . ALA A 1 535 ? -1.192  7.99    29.349  1   36.261  ? 541  ALA A O    1 ? 
ATOM   8193  C  CB   . ALA A 1 535 ? -2.663  5.282   30.335  1   43.747  ? 541  ALA A CB   1 ? 
ATOM   8194  H  H    . ALA A 1 535 ? -0.395  6.583   31.314  1   40.634  ? 541  ALA A H    1 c 
ATOM   8195  H  HA   . ALA A 1 535 ? -1.001  4.863   29.181  1   41.386  ? 541  ALA A HA   1 c 
ATOM   8196  H  HB1  . ALA A 1 535 ? -2.59   4.469   30.863  1   43.224  ? 541  ALA A HB1  1 c 
ATOM   8197  H  HB2  . ALA A 1 535 ? -2.963  6.007   30.904  1   43.192  ? 541  ALA A HB2  1 c 
ATOM   8198  H  HB3  . ALA A 1 535 ? -3.309  5.145   29.623  1   43.224  ? 541  ALA A HB3  1 c 
ATOM   8199  N  N    . TYR A 1 536 ? -1.491  6.684   27.538  1   42.312  ? 542  TYR A N    1 ? 
ATOM   8200  C  CA   . TYR A 1 536 ? -1.548  7.786   26.578  1   41.92   ? 542  TYR A CA   1 ? 
ATOM   8201  C  C    . TYR A 1 536 ? -2.807  7.682   25.704  1   36.226  ? 542  TYR A C    1 ? 
ATOM   8202  O  O    . TYR A 1 536 ? -3.128  6.636   25.159  1   41.693  ? 542  TYR A O    1 ? 
ATOM   8203  C  CB   . TYR A 1 536 ? -0.276  7.784   25.712  1   40.565  ? 542  TYR A CB   1 ? 
ATOM   8204  C  CG   . TYR A 1 536 ? 1.025   7.844   26.497  1   32.688  ? 542  TYR A CG   1 ? 
ATOM   8205  C  CD1  . TYR A 1 536 ? 1.51    9.05    26.973  1   32.858  ? 542  TYR A CD1  1 ? 
ATOM   8206  C  CD2  . TYR A 1 536 ? 1.806   6.718   26.671  1   32.01   ? 542  TYR A CD2  1 ? 
ATOM   8207  C  CE1  . TYR A 1 536 ? 2.678   9.108   27.715  1   33.388  ? 542  TYR A CE1  1 ? 
ATOM   8208  C  CE2  . TYR A 1 536 ? 3       6.768   27.372  1   34.518  ? 542  TYR A CE2  1 ? 
ATOM   8209  C  CZ   . TYR A 1 536 ? 3.441   7.973   27.88   1   32.028  ? 542  TYR A CZ   1 ? 
ATOM   8210  O  OH   . TYR A 1 536 ? 4.566   8.033   28.623  1   32.273  ? 542  TYR A OH   1 ? 
ATOM   8211  H  H    . TYR A 1 536 ? -1.558  5.829   27.223  1   41.317  ? 542  TYR A H    1 c 
ATOM   8212  H  HA   . TYR A 1 536 ? -1.582  8.64    27.081  1   40.599  ? 542  TYR A HA   1 c 
ATOM   8213  H  HB2  . TYR A 1 536 ? -0.276  6.97    25.161  1   38.818  ? 542  TYR A HB2  1 c 
ATOM   8214  H  HB3  . TYR A 1 536 ? -0.313  8.556   25.104  1   38.925  ? 542  TYR A HB3  1 c 
ATOM   8215  H  HD1  . TYR A 1 536 ? 0.988   9.829   26.873  1   32.996  ? 542  TYR A HD1  1 c 
ATOM   8216  H  HD2  . TYR A 1 536 ? 1.507   5.892   26.328  1   32.858  ? 542  TYR A HD2  1 c 
ATOM   8217  H  HE1  . TYR A 1 536 ? 2.977   9.931   28.061  1   32.955  ? 542  TYR A HE1  1 c 
ATOM   8218  H  HE2  . TYR A 1 536 ? 3.501   5.983   27.515  1   33.333  ? 542  TYR A HE2  1 c 
ATOM   8219  H  HH   . TYR A 1 536 ? 4.393   7.845   29.426  0   33      ? 542  TYR A HH   1 c 
ATOM   8220  N  N    . SER A 1 537 ? -3.49   8.806   25.547  1   39.176  ? 543  SER A N    1 ? 
ATOM   8221  C  CA   . SER A 1 537 ? -4.691  8.92    24.733  1   43.311  ? 543  SER A CA   1 ? 
ATOM   8222  C  C    . SER A 1 537 ? -4.559  10.147  23.833  1   40.009  ? 543  SER A C    1 ? 
ATOM   8223  O  O    . SER A 1 537 ? -4.636  11.273  24.332  1   43.162  ? 543  SER A O    1 ? 
ATOM   8224  C  CB   . SER A 1 537 ? -5.89   9.044   25.645  1   47.911  ? 543  SER A CB   1 ? 
ATOM   8225  O  OG   . SER A 1 537 ? -7.009  8.379   25.104  1   60.21   ? 543  SER A OG   1 ? 
ATOM   8226  H  H    . SER A 1 537 ? -3.191  9.557   25.974  1   39.371  ? 543  SER A H    1 c 
ATOM   8227  H  HA   . SER A 1 537 ? -4.786  8.11    24.171  1   42.661  ? 543  SER A HA   1 c 
ATOM   8228  H  HB2  . SER A 1 537 ? -5.674  8.657   26.515  1   49.367  ? 543  SER A HB2  1 c 
ATOM   8229  H  HB3  . SER A 1 537 ? -6.105  9.986   25.778  1   49.348  ? 543  SER A HB3  1 c 
ATOM   8230  H  HG   . SER A 1 537 ? -7.671  8.559   25.635  0   59.47   ? 543  SER A HG   1 c 
ATOM   8231  N  N    . LEU A 1 538 ? -4.323  9.944   22.523  1   41.075  ? 544  LEU A N    1 ? 
ATOM   8232  C  CA   . LEU A 1 538 ? -4.198  11.065  21.596  1   35.958  ? 544  LEU A CA   1 ? 
ATOM   8233  C  C    . LEU A 1 538 ? -5.569  11.341  20.964  1   40.154  ? 544  LEU A C    1 ? 
ATOM   8234  O  O    . LEU A 1 538 ? -6.135  10.516  20.249  1   40.852  ? 544  LEU A O    1 ? 
ATOM   8235  C  CB   . LEU A 1 538 ? -3.126  10.784  20.544  1   38.018  ? 544  LEU A CB   1 ? 
ATOM   8236  C  CG   . LEU A 1 538 ? -2.882  11.86   19.48   1   39.397  ? 544  LEU A CG   1 ? 
ATOM   8237  C  CD1  . LEU A 1 538 ? -2.149  13.056  20.048  1   39.971  ? 544  LEU A CD1  1 ? 
ATOM   8238  C  CD2  . LEU A 1 538 ? -2.106  11.258  18.308  1   45.919  ? 544  LEU A CD2  1 ? 
ATOM   8239  H  H    . LEU A 1 538 ? -4.239  9.092   22.202  1   39.666  ? 544  LEU A H    1 c 
ATOM   8240  H  HA   . LEU A 1 538 ? -3.927  11.865  22.114  1   38.107  ? 544  LEU A HA   1 c 
ATOM   8241  H  HB2  . LEU A 1 538 ? -2.276  10.619  21.013  1   37.857  ? 544  LEU A HB2  1 c 
ATOM   8242  H  HB3  . LEU A 1 538 ? -3.365  9.946   20.085  1   37.92   ? 544  LEU A HB3  1 c 
ATOM   8243  H  HG   . LEU A 1 538 ? -3.76   12.169  19.139  1   40.417  ? 544  LEU A HG   1 c 
ATOM   8244  H  HD11 . LEU A 1 538 ? -2.676  13.45   20.764  1   39.824  ? 544  LEU A HD11 1 c 
ATOM   8245  H  HD12 . LEU A 1 538 ? -2.01   13.715  19.348  1   39.806  ? 544  LEU A HD12 1 c 
ATOM   8246  H  HD13 . LEU A 1 538 ? -1.288  12.772  20.4    1   39.806  ? 544  LEU A HD13 1 c 
ATOM   8247  H  HD21 . LEU A 1 538 ? -2.624  10.54   17.909  1   43.852  ? 544  LEU A HD21 1 c 
ATOM   8248  H  HD22 . LEU A 1 538 ? -1.257  10.906  18.626  1   43.886  ? 544  LEU A HD22 1 c 
ATOM   8249  H  HD23 . LEU A 1 538 ? -1.94   11.946  17.641  1   43.886  ? 544  LEU A HD23 1 c 
ATOM   8250  N  N    . GLY A 1 539 ? -6.12   12.508  21.276  1   39.246  ? 545  GLY A N    1 ? 
ATOM   8251  C  CA   . GLY A 1 539 ? -7.345  12.978  20.637  1   46.975  ? 545  GLY A CA   1 ? 
ATOM   8252  C  C    . GLY A 1 539 ? -7.004  13.781  19.388  1   48.11   ? 545  GLY A C    1 ? 
ATOM   8253  O  O    . GLY A 1 539 ? -5.84   13.829  19.002  1   48.867  ? 545  GLY A O    1 ? 
ATOM   8254  H  H    . GLY A 1 539 ? -5.727  13.035  21.911  1   41.026  ? 545  GLY A H    1 c 
ATOM   8255  H  HA2  . GLY A 1 539 ? -7.911  12.21   20.398  1   45.255  ? 545  GLY A HA2  1 c 
ATOM   8256  H  HA3  . GLY A 1 539 ? -7.847  13.544  21.27   1   45.253  ? 545  GLY A HA3  1 c 
ATOM   8257  N  N    . ASP A 1 540 ? -8.018  14.408  18.785  1   51.503  ? 546  ASP A N    1 ? 
ATOM   8258  C  CA   . ASP A 1 540 ? -7.874  15.076  17.499  1   49.196  ? 546  ASP A CA   1 ? 
ATOM   8259  C  C    . ASP A 1 540 ? -7.084  16.372  17.683  1   47.312  ? 546  ASP A C    1 ? 
ATOM   8260  O  O    . ASP A 1 540 ? -6.433  16.829  16.746  1   48.952  ? 546  ASP A O    1 ? 
ATOM   8261  C  CB   . ASP A 1 540 ? -9.22   15.377  16.867  1   53.61   ? 546  ASP A CB   1 ? 
ATOM   8262  C  CG   . ASP A 1 540 ? -10.06  14.167  16.501  1   54.632  ? 546  ASP A CG   1 ? 
ATOM   8263  O  OD1  . ASP A 1 540 ? -9.494  13.162  16.052  1   54.132  ? 546  ASP A OD1  1 ? 
ATOM   8264  O  OD2  . ASP A 1 540 ? -11.279 14.271  16.638  1   65.491  ? 546  ASP A OD2  1 ? 
ATOM   8265  H  H    . ASP A 1 540 ? -8.836  14.421  19.194  1   50.152  ? 546  ASP A H    1 c 
ATOM   8266  H  HA   . ASP A 1 540 ? -7.371  14.483  16.896  1   50.077  ? 546  ASP A HA   1 c 
ATOM   8267  H  HB2  . ASP A 1 540 ? -9.738  15.931  17.488  1   52.861  ? 546  ASP A HB2  1 c 
ATOM   8268  H  HB3  . ASP A 1 540 ? -9.073  15.9    16.052  1   52.779  ? 546  ASP A HB3  1 c 
ATOM   8269  N  N    . LYS A 1 541 ? -7.163  16.935  18.897  1   40.064  ? 547  LYS A N    1 ? 
ATOM   8270  C  CA   . LYS A 1 541 ? -6.52   18.193  19.219  1   51.793  ? 547  LYS A CA   1 ? 
ATOM   8271  C  C    . LYS A 1 541 ? -5.81   18.168  20.576  1   48.191  ? 547  LYS A C    1 ? 
ATOM   8272  O  O    . LYS A 1 541 ? -5.438  19.234  21.059  1   52.055  ? 547  LYS A O    1 ? 
ATOM   8273  C  CB   . LYS A 1 541 ? -7.594  19.296  19.211  1   61.58   ? 547  LYS A CB   1 ? 
ATOM   8274  C  CG   . LYS A 1 541 ? -8.448  19.308  17.949  1   69.926  ? 547  LYS A CG   1 ? 
ATOM   8275  C  CD   . LYS A 1 541 ? -8.465  20.631  17.199  1   74.82   ? 547  LYS A CD   1 ? 
ATOM   8276  C  CE   . LYS A 1 541 ? -8.538  20.413  15.719  1   76.552  ? 547  LYS A CE   1 ? 
ATOM   8277  N  NZ   . LYS A 1 541 ? -7.507  21.228  15.066  1   76.207  ? 547  LYS A NZ   1 ? 
ATOM   8278  H  H    . LYS A 1 541 ? -7.663  16.528  19.544  1   44.28   ? 547  LYS A H    1 c 
ATOM   8279  H  HA   . LYS A 1 541 ? -5.85   18.395  18.518  1   50.125  ? 547  LYS A HA   1 c 
ATOM   8280  H  HB2  . LYS A 1 541 ? -8.183  19.173  19.986  1   60.917  ? 547  LYS A HB2  1 c 
ATOM   8281  H  HB3  . LYS A 1 541 ? -7.156  20.169  19.304  1   61.066  ? 547  LYS A HB3  1 c 
ATOM   8282  H  HG2  . LYS A 1 541 ? -8.122  18.61   17.346  1   68.453  ? 547  LYS A HG2  1 c 
ATOM   8283  H  HG3  . LYS A 1 541 ? -9.369  19.075  18.198  1   68.876  ? 547  LYS A HG3  1 c 
ATOM   8284  H  HD2  . LYS A 1 541 ? -9.244  21.156  17.487  1   74.046  ? 547  LYS A HD2  1 c 
ATOM   8285  H  HD3  . LYS A 1 541 ? -7.654  21.14   17.414  1   73.934  ? 547  LYS A HD3  1 c 
ATOM   8286  H  HE2  . LYS A 1 541 ? -8.395  19.476  15.494  1   75.969  ? 547  LYS A HE2  1 c 
ATOM   8287  H  HE3  . LYS A 1 541 ? -9.415  20.679  15.388  1   76.053  ? 547  LYS A HE3  1 c 
ATOM   8288  H  HZ1  . LYS A 1 541 ? -6.684  20.956  15.33   1   76.29   ? 547  LYS A HZ1  1 c 
ATOM   8289  H  HZ2  . LYS A 1 541 ? -7.618  22.101  15.284  1   76.283  ? 547  LYS A HZ2  1 c 
ATOM   8290  H  HZ3  . LYS A 1 541 ? -7.573  21.138  14.167  1   76.303  ? 547  LYS A HZ3  1 c 
ATOM   8291  N  N    . GLN A 1 542 ? -5.609  16.992  21.207  1   42.09   ? 548  GLN A N    1 ? 
ATOM   8292  C  CA   . GLN A 1 542 ? -4.941  16.976  22.491  1   44.891  ? 548  GLN A CA   1 ? 
ATOM   8293  C  C    . GLN A 1 542 ? -4.3    15.613  22.759  1   41.118  ? 548  GLN A C    1 ? 
ATOM   8294  O  O    . GLN A 1 542 ? -4.685  14.61   22.166  1   44.559  ? 548  GLN A O    1 ? 
ATOM   8295  C  CB   . GLN A 1 542 ? -5.965  17.349  23.569  1   48.462  ? 548  GLN A CB   1 ? 
ATOM   8296  C  CG   . GLN A 1 542 ? -6.982  16.243  23.827  1   53.041  ? 548  GLN A CG   1 ? 
ATOM   8297  C  CD   . GLN A 1 542 ? -7.907  16.546  24.98   1   60.008  ? 548  GLN A CD   1 ? 
ATOM   8298  O  OE1  . GLN A 1 542 ? -7.842  17.606  25.609  1   56.721  ? 548  GLN A OE1  1 ? 
ATOM   8299  N  NE2  . GLN A 1 542 ? -8.789  15.599  25.262  1   67.114  ? 548  GLN A NE2  1 ? 
ATOM   8300  H  H    . GLN A 1 542 ? -5.881  16.205  20.83   1   44.057  ? 548  GLN A H    1 c 
ATOM   8301  H  HA   . GLN A 1 542 ? -4.225  17.661  22.48   1   44.258  ? 548  GLN A HA   1 c 
ATOM   8302  H  HB2  . GLN A 1 542 ? -5.488  17.546  24.402  1   48.66   ? 548  GLN A HB2  1 c 
ATOM   8303  H  HB3  . GLN A 1 542 ? -6.438  18.163  23.296  1   48.642  ? 548  GLN A HB3  1 c 
ATOM   8304  H  HG2  . GLN A 1 542 ? -7.52   16.104  23.018  1   53.446  ? 548  GLN A HG2  1 c 
ATOM   8305  H  HG3  . GLN A 1 542 ? -6.51   15.405  24.019  1   53.349  ? 548  GLN A HG3  1 c 
ATOM   8306  H  HE21 . GLN A 1 542 ? -9.356  15.71   25.934  1   64.753  ? 548  GLN A HE21 1 c 
ATOM   8307  H  HE22 . GLN A 1 542 ? -8.812  14.855  24.78   1   64.73   ? 548  GLN A HE22 1 c 
ATOM   8308  N  N    . LEU A 1 543 ? -3.361  15.592  23.711  1   37.413  ? 549  LEU A N    1 ? 
ATOM   8309  C  CA   . LEU A 1 543 ? -2.868  14.356  24.311  1   40.427  ? 549  LEU A CA   1 ? 
ATOM   8310  C  C    . LEU A 1 543 ? -3.26   14.346  25.788  1   37.847  ? 549  LEU A C    1 ? 
ATOM   8311  O  O    . LEU A 1 543 ? -3.106  15.359  26.458  1   45.728  ? 549  LEU A O    1 ? 
ATOM   8312  C  CB   . LEU A 1 543 ? -1.352  14.257  24.151  1   31.947  ? 549  LEU A CB   1 ? 
ATOM   8313  C  CG   . LEU A 1 543 ? -0.657  13.049  24.778  1   34.045  ? 549  LEU A CG   1 ? 
ATOM   8314  C  CD1  . LEU A 1 543 ? -0.86   11.801  23.965  1   34.572  ? 549  LEU A CD1  1 ? 
ATOM   8315  C  CD2  . LEU A 1 543 ? 0.818   13.284  24.994  1   31.952  ? 549  LEU A CD2  1 ? 
ATOM   8316  H  H    . LEU A 1 543 ? -3.011  16.385  24.001  1   39.016  ? 549  LEU A H    1 c 
ATOM   8317  H  HA   . LEU A 1 543 ? -3.296  13.586  23.857  1   37.768  ? 549  LEU A HA   1 c 
ATOM   8318  H  HB2  . LEU A 1 543 ? -1.148  14.263  23.187  1   34.224  ? 549  LEU A HB2  1 c 
ATOM   8319  H  HB3  . LEU A 1 543 ? -0.954  15.073  24.532  1   34.265  ? 549  LEU A HB3  1 c 
ATOM   8320  H  HG   . LEU A 1 543 ? -1.064  12.891  25.669  1   33.369  ? 549  LEU A HG   1 c 
ATOM   8321  H  HD11 . LEU A 1 543 ? -1.801  11.558  23.972  1   34.428  ? 549  LEU A HD11 1 c 
ATOM   8322  H  HD12 . LEU A 1 543 ? -0.336  11.075  24.343  1   34.407  ? 549  LEU A HD12 1 c 
ATOM   8323  H  HD13 . LEU A 1 543 ? -0.576  11.963  23.05   1   34.496  ? 549  LEU A HD13 1 c 
ATOM   8324  H  HD21 . LEU A 1 543 ? 0.942   14.024  25.611  1   32.626  ? 549  LEU A HD21 1 c 
ATOM   8325  H  HD22 . LEU A 1 543 ? 1.241   13.497  24.146  1   32.578  ? 549  LEU A HD22 1 c 
ATOM   8326  H  HD23 . LEU A 1 543 ? 1.225   12.483  25.366  1   32.588  ? 549  LEU A HD23 1 c 
ATOM   8327  N  N    . THR A 1 544 ? -3.736  13.193  26.272  1   36.954  ? 550  THR A N    1 ? 
ATOM   8328  C  CA   . THR A 1 544 ? -3.956  12.972  27.696  1   38.519  ? 550  THR A CA   1 ? 
ATOM   8329  C  C    . THR A 1 544 ? -2.974  11.902  28.178  1   37.421  ? 550  THR A C    1 ? 
ATOM   8330  O  O    . THR A 1 544 ? -2.861  10.815  27.599  1   42.344  ? 550  THR A O    1 ? 
ATOM   8331  C  CB   . THR A 1 544 ? -5.406  12.567  27.991  1   41.097  ? 550  THR A CB   1 ? 
ATOM   8332  O  OG1  . THR A 1 544 ? -6.302  13.498  27.392  1   41.247  ? 550  THR A OG1  1 ? 
ATOM   8333  C  CG2  . THR A 1 544 ? -5.723  12.587  29.472  1   41.663  ? 550  THR A CG2  1 ? 
ATOM   8334  H  H    . THR A 1 544 ? -3.934  12.515  25.691  1   37.535  ? 550  THR A H    1 c 
ATOM   8335  H  HA   . THR A 1 544 ? -3.769  13.809  28.171  1   38.522  ? 550  THR A HA   1 c 
ATOM   8336  H  HB   . THR A 1 544 ? -5.581  11.664  27.631  1   40.752  ? 550  THR A HB   1 c 
ATOM   8337  H  HG1  . THR A 1 544 ? -6.149  14.3    27.711  0   41.4    ? 550  THR A HG1  1 c 
ATOM   8338  H  HG21 . THR A 1 544 ? -6.664  12.384  29.605  1   41.49   ? 550  THR A HG21 1 c 
ATOM   8339  H  HG22 . THR A 1 544 ? -5.528  13.468  29.834  1   41.49   ? 550  THR A HG22 1 c 
ATOM   8340  H  HG23 . THR A 1 544 ? -5.182  11.922  29.931  1   41.474  ? 550  THR A HG23 1 c 
ATOM   8341  N  N    . ILE A 1 545 ? -2.257  12.227  29.257  1   36.47   ? 551  ILE A N    1 ? 
ATOM   8342  C  CA   . ILE A 1 545 ? -1.332  11.306  29.899  1   38.87   ? 551  ILE A CA   1 ? 
ATOM   8343  C  C    . ILE A 1 545 ? -1.871  11.034  31.303  1   36.386  ? 551  ILE A C    1 ? 
ATOM   8344  O  O    . ILE A 1 545 ? -2.226  11.965  32.02   1   38.956  ? 551  ILE A O    1 ? 
ATOM   8345  C  CB   . ILE A 1 545 ? 0.073   11.922  29.983  1   34.027  ? 551  ILE A CB   1 ? 
ATOM   8346  C  CG1  . ILE A 1 545 ? 0.561   12.386  28.625  1   35.988  ? 551  ILE A CG1  1 ? 
ATOM   8347  C  CG2  . ILE A 1 545 ? 1.043   10.956  30.663  1   36.45   ? 551  ILE A CG2  1 ? 
ATOM   8348  C  CD1  . ILE A 1 545 ? 1.652   13.434  28.69   1   34.393  ? 551  ILE A CD1  1 ? 
ATOM   8349  H  H    . ILE A 1 545 ? -2.349  13.065  29.611  1   37.248  ? 551  ILE A H    1 c 
ATOM   8350  H  HA   . ILE A 1 545 ? -1.292  10.474  29.394  1   37.055  ? 551  ILE A HA   1 c 
ATOM   8351  H  HB   . ILE A 1 545 ? 0.007   12.714  30.55   1   35.769  ? 551  ILE A HB   1 c 
ATOM   8352  H  HG12 . ILE A 1 545 ? 0.9     11.612  28.133  1   35.141  ? 551  ILE A HG12 1 c 
ATOM   8353  H  HG13 . ILE A 1 545 ? -0.195  12.752  28.123  1   35.194  ? 551  ILE A HG13 1 c 
ATOM   8354  H  HG21 . ILE A 1 545 ? 1.947   11.309  30.607  1   35.71   ? 551  ILE A HG21 1 c 
ATOM   8355  H  HG22 . ILE A 1 545 ? 1.007   10.092  30.218  1   35.719  ? 551  ILE A HG22 1 c 
ATOM   8356  H  HG23 . ILE A 1 545 ? 0.798   10.847  31.597  1   35.722  ? 551  ILE A HG23 1 c 
ATOM   8357  H  HD11 . ILE A 1 545 ? 1.325   14.215  29.176  1   34.859  ? 551  ILE A HD11 1 c 
ATOM   8358  H  HD12 . ILE A 1 545 ? 1.905   13.698  27.786  1   34.859  ? 551  ILE A HD12 1 c 
ATOM   8359  H  HD13 . ILE A 1 545 ? 2.431   13.069  29.151  1   34.863  ? 551  ILE A HD13 1 c 
ATOM   8360  N  N    . THR A 1 546 ? -1.911  9.773   31.707  1   37.577  ? 552  THR A N    1 ? 
ATOM   8361  C  CA   . THR A 1 546 ? -2.35   9.472   33.066  1   37.405  ? 552  THR A CA   1 ? 
ATOM   8362  C  C    . THR A 1 546 ? -1.342  8.544   33.731  1   36.105  ? 552  THR A C    1 ? 
ATOM   8363  O  O    . THR A 1 546 ? -0.749  7.685   33.067  1   38.847  ? 552  THR A O    1 ? 
ATOM   8364  C  CB   . THR A 1 546 ? -3.749  8.859   33.102  1   38.426  ? 552  THR A CB   1 ? 
ATOM   8365  O  OG1  . THR A 1 546 ? -3.719  7.638   32.369  1   37.831  ? 552  THR A OG1  1 ? 
ATOM   8366  C  CG2  . THR A 1 546 ? -4.833  9.815   32.62   1   41.717  ? 552  THR A CG2  1 ? 
ATOM   8367  H  H    . THR A 1 546 ? -1.669  9.092   31.148  1   37.259  ? 552  THR A H    1 c 
ATOM   8368  H  HA   . THR A 1 546 ? -2.374  10.311  33.569  1   37.433  ? 552  THR A HA   1 c 
ATOM   8369  H  HB   . THR A 1 546 ? -3.958  8.647   34.043  1   38.697  ? 552  THR A HB   1 c 
ATOM   8370  H  HG1  . THR A 1 546 ? -3.485  7.833   31.549  0   37.86   ? 552  THR A HG1  1 c 
ATOM   8371  H  HG21 . THR A 1 546 ? -5.699  9.377   32.671  1   40.719  ? 552  THR A HG21 1 c 
ATOM   8372  H  HG22 . THR A 1 546 ? -4.654  10.071  31.7    1   40.719  ? 552  THR A HG22 1 c 
ATOM   8373  H  HG23 . THR A 1 546 ? -4.838  10.609  33.181  1   40.719  ? 552  THR A HG23 1 c 
ATOM   8374  N  N    . ASP A 1 547 ? -1.143  8.781   35.032  1   37.133  ? 553  ASP A N    1 ? 
ATOM   8375  C  CA   . ASP A 1 547 ? -0.318  7.958   35.903  1   42.27   ? 553  ASP A CA   1 ? 
ATOM   8376  C  C    . ASP A 1 547 ? -1.208  7.484   37.05   1   43.291  ? 553  ASP A C    1 ? 
ATOM   8377  O  O    . ASP A 1 547 ? -1.797  8.318   37.743  1   48.955  ? 553  ASP A O    1 ? 
ATOM   8378  C  CB   . ASP A 1 547 ? 0.897   8.709   36.434  1   39.179  ? 553  ASP A CB   1 ? 
ATOM   8379  C  CG   . ASP A 1 547 ? 2.048   8.969   35.466  1   37.853  ? 553  ASP A CG   1 ? 
ATOM   8380  O  OD1  . ASP A 1 547 ? 2.611   7.971   34.93   1   34.468  ? 553  ASP A OD1  1 ? 
ATOM   8381  O  OD2  . ASP A 1 547 ? 2.436   10.16   35.325  1   31.296  ? 553  ASP A OD2  1 ? 
ATOM   8382  H  H    . ASP A 1 547 ? -1.552  9.51    35.401  1   38.011  ? 553  ASP A H    1 c 
ATOM   8383  H  HA   . ASP A 1 547 ? -0.003  7.179   35.395  1   40.807  ? 553  ASP A HA   1 c 
ATOM   8384  H  HB2  . ASP A 1 547 ? 0.593   9.575   36.776  1   39.553  ? 553  ASP A HB2  1 c 
ATOM   8385  H  HB3  . ASP A 1 547 ? 1.259   8.206   37.192  1   39.536  ? 553  ASP A HB3  1 c 
ATOM   8386  N  N    . ASN A 1 548 ? -1.289  6.16    37.219  1   44.849  ? 554  ASN A N    1 ? 
ATOM   8387  C  CA   . ASN A 1 548 ? -2.25   5.5     38.099  1   42.846  ? 554  ASN A CA   1 ? 
ATOM   8388  C  C    . ASN A 1 548 ? -1.547  4.435   38.932  1   41.357  ? 554  ASN A C    1 ? 
ATOM   8389  O  O    . ASN A 1 548 ? -1.287  3.338   38.445  1   39.832  ? 554  ASN A O    1 ? 
ATOM   8390  C  CB   . ASN A 1 548 ? -3.354  4.813   37.304  1   50.091  ? 554  ASN A CB   1 ? 
ATOM   8391  C  CG   . ASN A 1 548 ? -4.622  4.717   38.115  1   61.422  ? 554  ASN A CG   1 ? 
ATOM   8392  O  OD1  . ASN A 1 548 ? -4.805  3.759   38.862  1   58.362  ? 554  ASN A OD1  1 ? 
ATOM   8393  N  ND2  . ASN A 1 548 ? -5.504  5.697   37.991  1   70.232  ? 554  ASN A ND2  1 ? 
ATOM   8394  H  H    . ASN A 1 548 ? -0.704  5.632   36.757  1   43.956  ? 554  ASN A H    1 c 
ATOM   8395  H  HA   . ASN A 1 548 ? -2.662  6.169   38.691  1   44.339  ? 554  ASN A HA   1 c 
ATOM   8396  H  HB2  . ASN A 1 548 ? -3.53   5.324   36.489  1   50.749  ? 554  ASN A HB2  1 c 
ATOM   8397  H  HB3  . ASN A 1 548 ? -3.066  3.916   37.044  1   50.558  ? 554  ASN A HB3  1 c 
ATOM   8398  H  HD21 . ASN A 1 548 ? -6.092  5.845   38.639  1   67.261  ? 554  ASN A HD21 1 c 
ATOM   8399  H  HD22 . ASN A 1 548 ? -5.508  6.201   37.262  1   67.2    ? 554  ASN A HD22 1 c 
ATOM   8400  N  N    . PHE A 1 549 ? -1.298  4.742   40.208  1   47.423  ? 555  PHE A N    1 ? 
ATOM   8401  C  CA   . PHE A 1 549 ? -0.297  4.003   40.955  1   48.129  ? 555  PHE A CA   1 ? 
ATOM   8402  C  C    . PHE A 1 549 ? -0.741  3.632   42.365  1   41.963  ? 555  PHE A C    1 ? 
ATOM   8403  O  O    . PHE A 1 549 ? -1.48   4.369   43.007  1   38.067  ? 555  PHE A O    1 ? 
ATOM   8404  C  CB   . PHE A 1 549 ? 0.956   4.866   41.017  1   44.123  ? 555  PHE A CB   1 ? 
ATOM   8405  C  CG   . PHE A 1 549 ? 0.828   6.169   41.779  1   44.463  ? 555  PHE A CG   1 ? 
ATOM   8406  C  CD1  . PHE A 1 549 ? 1.016   6.207   43.165  1   45.963  ? 555  PHE A CD1  1 ? 
ATOM   8407  C  CD2  . PHE A 1 549 ? 0.527   7.351   41.115  1   41.357  ? 555  PHE A CD2  1 ? 
ATOM   8408  C  CE1  . PHE A 1 549 ? 0.918   7.401   43.866  1   38.742  ? 555  PHE A CE1  1 ? 
ATOM   8409  C  CE2  . PHE A 1 549 ? 0.42    8.537   41.819  1   44.617  ? 555  PHE A CE2  1 ? 
ATOM   8410  C  CZ   . PHE A 1 549 ? 0.626   8.561   43.199  1   43.548  ? 555  PHE A CZ   1 ? 
ATOM   8411  H  H    . PHE A 1 549 ? -1.757  5.416   40.62   1   46.006  ? 555  PHE A H    1 c 
ATOM   8412  H  HA   . PHE A 1 549 ? -0.084  3.171   40.46   1   45.896  ? 555  PHE A HA   1 c 
ATOM   8413  H  HB2  . PHE A 1 549 ? 1.675   4.334   41.425  1   45.022  ? 555  PHE A HB2  1 c 
ATOM   8414  H  HB3  . PHE A 1 549 ? 1.23    5.07    40.096  1   44.976  ? 555  PHE A HB3  1 c 
ATOM   8415  H  HD1  . PHE A 1 549 ? 1.227   5.411   43.625  1   43.78   ? 555  PHE A HD1  1 c 
ATOM   8416  H  HD2  . PHE A 1 549 ? 0.397   7.343   40.18   1   42.818  ? 555  PHE A HD2  1 c 
ATOM   8417  H  HE1  . PHE A 1 549 ? 1.048   7.411   44.801  1   41.483  ? 555  PHE A HE1  1 c 
ATOM   8418  H  HE2  . PHE A 1 549 ? 0.219   9.338   41.36   1   43.58   ? 555  PHE A HE2  1 c 
ATOM   8419  H  HZ   . PHE A 1 549 ? 0.545   9.372   43.675  1   42.622  ? 555  PHE A HZ   1 c 
ATOM   8420  N  N    . SER A 1 550 ? -0.167  2.515   42.828  1   41.349  ? 556  SER A N    1 ? 
ATOM   8421  C  CA   . SER A 1 550 ? -0.231  2.053   44.202  1   46.56   ? 556  SER A CA   1 ? 
ATOM   8422  C  C    . SER A 1 550 ? 1.187   1.776   44.708  1   40.729  ? 556  SER A C    1 ? 
ATOM   8423  O  O    . SER A 1 550 ? 1.907   0.985   44.107  1   42.586  ? 556  SER A O    1 ? 
ATOM   8424  C  CB   . SER A 1 550 ? -1.111  0.811   44.255  1   50.618  ? 556  SER A CB   1 ? 
ATOM   8425  O  OG   . SER A 1 550 ? -1.036  0.164   45.512  1   45.816  ? 556  SER A OG   1 ? 
ATOM   8426  H  H    . SER A 1 550 ? 0.301   2.001   42.234  1   42.688  ? 556  SER A H    1 c 
ATOM   8427  H  HA   . SER A 1 550 ? -0.639  2.762   44.761  1   44.948  ? 556  SER A HA   1 c 
ATOM   8428  H  HB2  . SER A 1 550 ? -2.037  1.066   44.079  1   48.51   ? 556  SER A HB2  1 c 
ATOM   8429  H  HB3  . SER A 1 550 ? -0.831  0.19    43.555  1   48.51   ? 556  SER A HB3  1 c 
ATOM   8430  H  HG   . SER A 1 550 ? -1.515  -0.51   45.516  0   45.72   ? 556  SER A HG   1 c 
ATOM   8431  N  N    . LEU A 1 551 ? 1.595   2.443   45.794  1   38.398  ? 557  LEU A N    1 ? 
ATOM   8432  C  CA   . LEU A 1 551 ? 2.921   2.252   46.369  1   43.919  ? 557  LEU A CA   1 ? 
ATOM   8433  C  C    . LEU A 1 551 ? 2.814   1.43    47.66   1   51.276  ? 557  LEU A C    1 ? 
ATOM   8434  O  O    . LEU A 1 551 ? 1.808   1.536   48.344  1   44.862  ? 557  LEU A O    1 ? 
ATOM   8435  C  CB   . LEU A 1 551 ? 3.524   3.62    46.673  1   42.135  ? 557  LEU A CB   1 ? 
ATOM   8436  C  CG   . LEU A 1 551 ? 3.46    4.656   45.55   1   41.161  ? 557  LEU A CG   1 ? 
ATOM   8437  C  CD1  . LEU A 1 551 ? 3.996   5.989   46.029  1   43.554  ? 557  LEU A CD1  1 ? 
ATOM   8438  C  CD2  . LEU A 1 551 ? 4.263   4.115   44.39   1   44.26   ? 557  LEU A CD2  1 ? 
ATOM   8439  H  H    . LEU A 1 551 ? 1.026   3.038   46.192  1   40.218  ? 557  LEU A H    1 c 
ATOM   8440  H  HA   . LEU A 1 551 ? 3.493   1.772   45.721  1   43.693  ? 557  LEU A HA   1 c 
ATOM   8441  H  HB2  . LEU A 1 551 ? 3.063   3.989   47.461  1   42.361  ? 557  LEU A HB2  1 c 
ATOM   8442  H  HB3  . LEU A 1 551 ? 4.469   3.489   46.921  1   42.327  ? 557  LEU A HB3  1 c 
ATOM   8443  H  HG   . LEU A 1 551 ? 2.516   4.768   45.269  1   42.33   ? 557  LEU A HG   1 c 
ATOM   8444  H  HD11 . LEU A 1 551 ? 3.592   6.214   46.883  1   42.898  ? 557  LEU A HD11 1 c 
ATOM   8445  H  HD12 . LEU A 1 551 ? 3.782   6.679   45.377  1   42.847  ? 557  LEU A HD12 1 c 
ATOM   8446  H  HD13 . LEU A 1 551 ? 4.961   5.932   46.134  1   42.847  ? 557  LEU A HD13 1 c 
ATOM   8447  H  HD21 . LEU A 1 551 ? 3.814   3.34    44.014  1   43.319  ? 557  LEU A HD21 1 c 
ATOM   8448  H  HD22 . LEU A 1 551 ? 5.149   3.858   44.699  1   43.304  ? 557  LEU A HD22 1 c 
ATOM   8449  H  HD23 . LEU A 1 551 ? 4.348   4.802   43.706  1   43.314  ? 557  LEU A HD23 1 c 
ATOM   8450  N  N    . LYS A 1 552 ? 3.883   0.693   48.025  1   48.888  ? 558  LYS A N    1 ? 
ATOM   8451  C  CA   . LYS A 1 552 ? 3.945   -0.029  49.286  1   46.989  ? 558  LYS A CA   1 ? 
ATOM   8452  C  C    . LYS A 1 552 ? 4.179   0.916   50.457  1   46.965  ? 558  LYS A C    1 ? 
ATOM   8453  O  O    . LYS A 1 552 ? 3.85    0.618   51.596  1   45.3    ? 558  LYS A O    1 ? 
ATOM   8454  C  CB   . LYS A 1 552 ? 5.081   -1.055  49.31   1   47.413  ? 558  LYS A CB   1 ? 
ATOM   8455  C  CG   . LYS A 1 552 ? 4.872   -2.211  48.393  1   46.874  ? 558  LYS A CG   1 ? 
ATOM   8456  C  CD   . LYS A 1 552 ? 6.12    -3.051  48.163  1   50.434  ? 558  LYS A CD   1 ? 
ATOM   8457  C  CE   . LYS A 1 552 ? 5.846   -4.166  47.19   1   55.481  ? 558  LYS A CE   1 ? 
ATOM   8458  N  NZ   . LYS A 1 552 ? 6.92    -5.164  47.264  1   58.958  ? 558  LYS A NZ   1 ? 
ATOM   8459  H  H    . LYS A 1 552 ? 4.598   0.643   47.458  1   48.884  ? 558  LYS A H    1 c 
ATOM   8460  H  HA   . LYS A 1 552 ? 3.083   -0.499  49.423  1   47.432  ? 558  LYS A HA   1 c 
ATOM   8461  H  HB2  . LYS A 1 552 ? 5.918   -0.607  49.063  1   47.191  ? 558  LYS A HB2  1 c 
ATOM   8462  H  HB3  . LYS A 1 552 ? 5.183   -1.397  50.224  1   47.19   ? 558  LYS A HB3  1 c 
ATOM   8463  H  HG2  . LYS A 1 552 ? 4.166   -2.782  48.767  1   47.785  ? 558  LYS A HG2  1 c 
ATOM   8464  H  HG3  . LYS A 1 552 ? 4.554   -1.87   47.528  1   47.789  ? 558  LYS A HG3  1 c 
ATOM   8465  H  HD2  . LYS A 1 552 ? 6.837   -2.481  47.81   1   50.714  ? 558  LYS A HD2  1 c 
ATOM   8466  H  HD3  . LYS A 1 552 ? 6.417   -3.433  49.018  1   50.749  ? 558  LYS A HD3  1 c 
ATOM   8467  H  HE2  . LYS A 1 552 ? 4.998   -4.593  47.403  1   54.983  ? 558  LYS A HE2  1 c 
ATOM   8468  H  HE3  . LYS A 1 552 ? 5.797   -3.813  46.284  1   55.061  ? 558  LYS A HE3  1 c 
ATOM   8469  H  HZ1  . LYS A 1 552 ? 6.935   -5.539  48.089  1   57.803  ? 558  LYS A HZ1  1 c 
ATOM   8470  H  HZ2  . LYS A 1 552 ? 7.719   -4.767  47.103  1   57.807  ? 558  LYS A HZ2  1 c 
ATOM   8471  H  HZ3  . LYS A 1 552 ? 6.779   -5.811  46.646  1   57.842  ? 558  LYS A HZ3  1 c 
ATOM   8472  N  N    . SER A 1 553 ? 4.788   2.055   50.18   1   49.214  ? 559  SER A N    1 ? 
ATOM   8473  C  CA   . SER A 1 553 ? 5.142   3.003   51.214  1   49.062  ? 559  SER A CA   1 ? 
ATOM   8474  C  C    . SER A 1 553 ? 5.299   4.352   50.526  1   51.748  ? 559  SER A C    1 ? 
ATOM   8475  O  O    . SER A 1 553 ? 5.871   4.396   49.443  1   39.876  ? 559  SER A O    1 ? 
ATOM   8476  C  CB   . SER A 1 553 ? 6.435   2.566   51.921  1   50.546  ? 559  SER A CB   1 ? 
ATOM   8477  O  OG   . SER A 1 553 ? 7.098   3.668   52.532  1   51.912  ? 559  SER A OG   1 ? 
ATOM   8478  H  H    . SER A 1 553 ? 5.008   2.249   49.314  1   48.66   ? 559  SER A H    1 c 
ATOM   8479  H  HA   . SER A 1 553 ? 4.405   3.057   51.874  1   49.787  ? 559  SER A HA   1 c 
ATOM   8480  H  HB2  . SER A 1 553 ? 6.219   1.901   52.603  1   50.532  ? 559  SER A HB2  1 c 
ATOM   8481  H  HB3  . SER A 1 553 ? 7.032   2.15    51.271  1   50.526  ? 559  SER A HB3  1 c 
ATOM   8482  H  HG   . SER A 1 553 ? 7.761   3.617   52.851  0   52.47   ? 559  SER A HG   1 c 
ATOM   8483  N  N    . ALA A 1 554 ? 4.813   5.422   51.163  1   47.056  ? 560  ALA A N    1 ? 
ATOM   8484  C  CA   . ALA A 1 554 ? 4.912   6.757   50.613  1   48.544  ? 560  ALA A CA   1 ? 
ATOM   8485  C  C    . ALA A 1 554 ? 6.143   7.438   51.182  1   52.882  ? 560  ALA A C    1 ? 
ATOM   8486  O  O    . ALA A 1 554 ? 6.032   8.234   52.112  1   58.998  ? 560  ALA A O    1 ? 
ATOM   8487  C  CB   . ALA A 1 554 ? 3.649   7.542   50.928  1   54.226  ? 560  ALA A CB   1 ? 
ATOM   8488  H  H    . ALA A 1 554 ? 4.404   5.312   51.973  1   48.524  ? 560  ALA A H    1 c 
ATOM   8489  H  HA   . ALA A 1 554 ? 5.017   6.689   49.624  1   49.989  ? 560  ALA A HA   1 c 
ATOM   8490  H  HB1  . ALA A 1 554 ? 2.889   7.128   50.485  1   52.486  ? 560  ALA A HB1  1 c 
ATOM   8491  H  HB2  . ALA A 1 554 ? 3.497   7.547   51.888  1   52.513  ? 560  ALA A HB2  1 c 
ATOM   8492  H  HB3  . ALA A 1 554 ? 3.745   8.456   50.612  1   52.471  ? 560  ALA A HB3  1 c 
ATOM   8493  N  N    . LYS A 1 555 ? 7.308   7.119   50.608  1   57.276  ? 561  LYS A N    1 ? 
ATOM   8494  C  CA   . LYS A 1 555 ? 8.583   7.496   51.205  1   53.889  ? 561  LYS A CA   1 ? 
ATOM   8495  C  C    . LYS A 1 555 ? 8.986   8.896   50.765  1   48.245  ? 561  LYS A C    1 ? 
ATOM   8496  O  O    . LYS A 1 555 ? 9.447   9.675   51.578  1   49.418  ? 561  LYS A O    1 ? 
ATOM   8497  C  CB   . LYS A 1 555 ? 9.823   6.698   50.796  1   55.704  ? 561  LYS A CB   1 ? 
ATOM   8498  C  CG   . LYS A 1 555 ? 9.628   5.254   50.519  1   60.599  ? 561  LYS A CG   1 ? 
ATOM   8499  C  CD   . LYS A 1 555 ? 10.742  4.781   49.605  1   65.858  ? 561  LYS A CD   1 ? 
ATOM   8500  C  CE   . LYS A 1 555 ? 12.081  4.771   50.227  1   63.342  ? 561  LYS A CE   1 ? 
ATOM   8501  N  NZ   . LYS A 1 555 ? 12.876  3.77    49.501  1   66.65   ? 561  LYS A NZ   1 ? 
ATOM   8502  H  H    . LYS A 1 555 ? 7.308   6.667   49.814  1   55.382  ? 561  LYS A H    1 c 
ATOM   8503  H  HA   . LYS A 1 555 ? 8.491   7.479   52.192  1   53.781  ? 561  LYS A HA   1 c 
ATOM   8504  H  HB2  . LYS A 1 555 ? 10.211  7.113   49.996  1   56.416  ? 561  LYS A HB2  1 c 
ATOM   8505  H  HB3  . LYS A 1 555 ? 10.485  6.779   51.516  1   56.43   ? 561  LYS A HB3  1 c 
ATOM   8506  H  HG2  . LYS A 1 555 ? 9.65    4.751   51.362  1   60.561  ? 561  LYS A HG2  1 c 
ATOM   8507  H  HG3  . LYS A 1 555 ? 8.76    5.115   50.082  1   60.492  ? 561  LYS A HG3  1 c 
ATOM   8508  H  HD2  . LYS A 1 555 ? 10.528  3.877   49.299  1   63.972  ? 561  LYS A HD2  1 c 
ATOM   8509  H  HD3  . LYS A 1 555 ? 10.767  5.357   48.809  1   63.922  ? 561  LYS A HD3  1 c 
ATOM   8510  H  HE2  . LYS A 1 555 ? 12.502  5.645   50.149  1   64.668  ? 561  LYS A HE2  1 c 
ATOM   8511  H  HE3  . LYS A 1 555 ? 12.021  4.525   51.167  1   64.628  ? 561  LYS A HE3  1 c 
ATOM   8512  H  HZ1  . LYS A 1 555 ? 12.836  3.926   48.609  1   65.613  ? 561  LYS A HZ1  1 c 
ATOM   8513  H  HZ2  . LYS A 1 555 ? 12.56   2.938   49.674  1   65.604  ? 561  LYS A HZ2  1 c 
ATOM   8514  H  HZ3  . LYS A 1 555 ? 13.74   3.816   49.77   1   65.612  ? 561  LYS A HZ3  1 c 
ATOM   8515  N  N    . GLU A 1 556 ? 8.9     9.172   49.463  1   50.73   ? 562  GLU A N    1 ? 
ATOM   8516  C  CA   . GLU A 1 556 ? 9.299   10.469  48.925  1   56.74   ? 562  GLU A CA   1 ? 
ATOM   8517  C  C    . GLU A 1 556 ? 8.249   10.913  47.909  1   50.204  ? 562  GLU A C    1 ? 
ATOM   8518  O  O    . GLU A 1 556 ? 7.581   10.066  47.312  1   58.235  ? 562  GLU A O    1 ? 
ATOM   8519  C  CB   . GLU A 1 556 ? 10.692  10.36   48.294  1   57.277  ? 562  GLU A CB   1 ? 
ATOM   8520  C  CG   . GLU A 1 556 ? 11.353  11.698  47.983  1   62.831  ? 562  GLU A CG   1 ? 
ATOM   8521  C  CD   . GLU A 1 556 ? 11.874  12.378  49.23   1   74.239  ? 562  GLU A CD   1 ? 
ATOM   8522  O  OE1  . GLU A 1 556 ? 11.499  13.545  49.481  1   79.526  ? 562  GLU A OE1  1 ? 
ATOM   8523  O  OE2  . GLU A 1 556 ? 12.634  11.704  49.966  1   69.323  ? 562  GLU A OE2  1 ? 
ATOM   8524  H  H    . GLU A 1 556 ? 8.59    8.533   48.887  1   51.447  ? 562  GLU A H    1 c 
ATOM   8525  H  HA   . GLU A 1 556 ? 9.325   11.126  49.666  1   54.334  ? 562  GLU A HA   1 c 
ATOM   8526  H  HB2  . GLU A 1 556 ? 11.27   9.848   48.896  1   58.486  ? 562  GLU A HB2  1 c 
ATOM   8527  H  HB3  . GLU A 1 556 ? 10.615  9.857   47.459  1   58.299  ? 562  GLU A HB3  1 c 
ATOM   8528  H  HG2  . GLU A 1 556 ? 12.101  11.555  47.365  1   63.907  ? 562  GLU A HG2  1 c 
ATOM   8529  H  HG3  . GLU A 1 556 ? 10.705  12.288  47.547  1   63.768  ? 562  GLU A HG3  1 c 
ATOM   8530  N  N    . SER A 1 557 ? 8.092   12.238  47.75   1   44.345  ? 563  SER A N    1 ? 
ATOM   8531  C  CA   . SER A 1 557 ? 7.24    12.81   46.718  1   49.874  ? 563  SER A CA   1 ? 
ATOM   8532  C  C    . SER A 1 557 ? 7.618   12.203  45.373  1   45.523  ? 563  SER A C    1 ? 
ATOM   8533  O  O    . SER A 1 557 ? 8.813   12.124  45.069  1   41.333  ? 563  SER A O    1 ? 
ATOM   8534  C  CB   . SER A 1 557 ? 7.403   14.297  46.618  1   53.1    ? 563  SER A CB   1 ? 
ATOM   8535  O  OG   . SER A 1 557 ? 6.802   14.952  47.715  1   68.147  ? 563  SER A OG   1 ? 
ATOM   8536  H  H    . SER A 1 557 ? 8.534   12.805  48.314  1   47.17   ? 563  SER A H    1 c 
ATOM   8537  H  HA   . SER A 1 557 ? 6.294   12.595  46.922  1   48.444  ? 563  SER A HA   1 c 
ATOM   8538  H  HB2  . SER A 1 557 ? 8.349   14.513  46.596  1   55.91   ? 563  SER A HB2  1 c 
ATOM   8539  H  HB3  . SER A 1 557 ? 6.998   14.612  45.789  1   55.507  ? 563  SER A HB3  1 c 
ATOM   8540  H  HG   . SER A 1 557 ? 6.966   15.788  47.667  0   67.44   ? 563  SER A HG   1 c 
ATOM   8541  N  N    . ASN A 1 558 ? 6.612   11.83   44.571  1   43.04   ? 564  ASN A N    1 ? 
ATOM   8542  C  CA   . ASN A 1 558 ? 6.891   11.418  43.2    1   43.322  ? 564  ASN A CA   1 ? 
ATOM   8543  C  C    . ASN A 1 558 ? 7.373   12.626  42.4    1   40.316  ? 564  ASN A C    1 ? 
ATOM   8544  O  O    . ASN A 1 558 ? 7.019   13.766  42.7    1   44.626  ? 564  ASN A O    1 ? 
ATOM   8545  C  CB   . ASN A 1 558 ? 5.684   10.789  42.527  1   42.011  ? 564  ASN A CB   1 ? 
ATOM   8546  C  CG   . ASN A 1 558 ? 5.258   9.495   43.171  1   41.507  ? 564  ASN A CG   1 ? 
ATOM   8547  O  OD1  . ASN A 1 558 ? 6.089   8.69    43.62   1   39.482  ? 564  ASN A OD1  1 ? 
ATOM   8548  N  ND2  . ASN A 1 558 ? 3.957   9.278   43.189  1   39.407  ? 564  ASN A ND2  1 ? 
ATOM   8549  H  H    . ASN A 1 558 ? 5.75    11.832  44.876  1   43.738  ? 564  ASN A H    1 c 
ATOM   8550  H  HA   . ASN A 1 558 ? 7.608   10.744  43.217  1   42.444  ? 564  ASN A HA   1 c 
ATOM   8551  H  HB2  . ASN A 1 558 ? 4.94    11.422  42.557  1   42.195  ? 564  ASN A HB2  1 c 
ATOM   8552  H  HB3  . ASN A 1 558 ? 5.896   10.62   41.587  1   42.18   ? 564  ASN A HB3  1 c 
ATOM   8553  H  HD21 . ASN A 1 558 ? 3.628   8.621   43.688  1   40.045  ? 564  ASN A HD21 1 c 
ATOM   8554  H  HD22 . ASN A 1 558 ? 3.41    9.782   42.704  1   40.073  ? 564  ASN A HD22 1 c 
ATOM   8555  N  N    . GLN A 1 559 ? 8.205   12.38   41.39   1   41.638  ? 565  GLN A N    1 ? 
ATOM   8556  C  CA   . GLN A 1 559 ? 8.627   13.461  40.508  1   40.777  ? 565  GLN A CA   1 ? 
ATOM   8557  C  C    . GLN A 1 559 ? 8.346   13.028  39.077  1   38.19   ? 565  GLN A C    1 ? 
ATOM   8558  O  O    . GLN A 1 559 ? 8.745   11.943  38.661  1   39.926  ? 565  GLN A O    1 ? 
ATOM   8559  C  CB   . GLN A 1 559 ? 10.083  13.872  40.749  1   37.255  ? 565  GLN A CB   1 ? 
ATOM   8560  C  CG   . GLN A 1 559 ? 10.69   14.707  39.634  1   42.311  ? 565  GLN A CG   1 ? 
ATOM   8561  C  CD   . GLN A 1 559 ? 12.069  15.221  39.989  1   41.962  ? 565  GLN A CD   1 ? 
ATOM   8562  O  OE1  . GLN A 1 559 ? 12.466  15.221  41.145  1   46.845  ? 565  GLN A OE1  1 ? 
ATOM   8563  N  NE2  . GLN A 1 559 ? 12.83   15.679  39.012  1   41.555  ? 565  GLN A NE2  1 ? 
ATOM   8564  H  H    . GLN A 1 559 ? 8.516   11.534  41.243  1   41.131  ? 565  GLN A H    1 c 
ATOM   8565  H  HA   . GLN A 1 559 ? 8.066   14.251  40.704  1   39.864  ? 565  GLN A HA   1 c 
ATOM   8566  H  HB2  . GLN A 1 559 ? 10.126  14.381  41.585  1   39.192  ? 565  GLN A HB2  1 c 
ATOM   8567  H  HB3  . GLN A 1 559 ? 10.621  13.062  40.867  1   39.158  ? 565  GLN A HB3  1 c 
ATOM   8568  H  HG2  . GLN A 1 559 ? 10.757  14.165  38.819  1   41.014  ? 565  GLN A HG2  1 c 
ATOM   8569  H  HG3  . GLN A 1 559 ? 10.104  15.47   39.441  1   41.025  ? 565  GLN A HG3  1 c 
ATOM   8570  H  HE21 . GLN A 1 559 ? 13.709  15.729  39.122  1   41.718  ? 565  GLN A HE21 1 c 
ATOM   8571  H  HE22 . GLN A 1 559 ? 12.461  15.938  38.248  1   41.689  ? 565  GLN A HE22 1 c 
ATOM   8572  N  N    . VAL A 1 560 ? 7.599   13.869  38.358  1   38.009  ? 566  VAL A N    1 ? 
ATOM   8573  C  CA   . VAL A 1 560 ? 7.277   13.594  36.977  1   36.78   ? 566  VAL A CA   1 ? 
ATOM   8574  C  C    . VAL A 1 560 ? 7.967   14.632  36.083  1   38.281  ? 566  VAL A C    1 ? 
ATOM   8575  O  O    . VAL A 1 560 ? 7.652   15.818  36.159  1   36.78   ? 566  VAL A O    1 ? 
ATOM   8576  C  CB   . VAL A 1 560 ? 5.749   13.548  36.777  1   38.832  ? 566  VAL A CB   1 ? 
ATOM   8577  C  CG1  . VAL A 1 560 ? 5.365   13.248  35.316  1   35.553  ? 566  VAL A CG1  1 ? 
ATOM   8578  C  CG2  . VAL A 1 560 ? 5.104   12.544  37.746  1   38.697  ? 566  VAL A CG2  1 ? 
ATOM   8579  H  H    . VAL A 1 560 ? 7.282   14.636  38.74   1   37.808  ? 566  VAL A H    1 c 
ATOM   8580  H  HA   . VAL A 1 560 ? 7.634   12.716  36.752  1   37.704  ? 566  VAL A HA   1 c 
ATOM   8581  H  HB   . VAL A 1 560 ? 5.402   14.444  37      1   37.795  ? 566  VAL A HB   1 c 
ATOM   8582  H  HG11 . VAL A 1 560 ? 5.793   12.424  35.03   1   36.487  ? 566  VAL A HG11 1 c 
ATOM   8583  H  HG12 . VAL A 1 560 ? 5.657   13.978  34.746  1   36.51   ? 566  VAL A HG12 1 c 
ATOM   8584  H  HG13 . VAL A 1 560 ? 4.4     13.151  35.248  1   36.487  ? 566  VAL A HG13 1 c 
ATOM   8585  H  HG21 . VAL A 1 560 ? 4.156   12.463  37.546  1   38.743  ? 566  VAL A HG21 1 c 
ATOM   8586  H  HG22 . VAL A 1 560 ? 5.215   12.854  38.66   1   38.74   ? 566  VAL A HG22 1 c 
ATOM   8587  H  HG23 . VAL A 1 560 ? 5.529   11.676  37.646  1   38.766  ? 566  VAL A HG23 1 c 
ATOM   8588  N  N    . ASN A 1 561 ? 8.763   14.118  35.124  1   37.24   ? 567  ASN A N    1 ? 
ATOM   8589  C  CA   . ASN A 1 561 ? 9.723   14.879  34.326  1   39.757  ? 567  ASN A CA   1 ? 
ATOM   8590  C  C    . ASN A 1 561 ? 9.298   14.914  32.859  1   37.752  ? 567  ASN A C    1 ? 
ATOM   8591  O  O    . ASN A 1 561 ? 8.762   13.941  32.332  1   41.631  ? 567  ASN A O    1 ? 
ATOM   8592  C  CB   . ASN A 1 561 ? 11.119  14.261  34.443  1   36.995  ? 567  ASN A CB   1 ? 
ATOM   8593  C  CG   . ASN A 1 561 ? 11.691  14.439  35.839  1   40.847  ? 567  ASN A CG   1 ? 
ATOM   8594  O  OD1  . ASN A 1 561 ? 11.541  15.514  36.433  1   34.256  ? 567  ASN A OD1  1 ? 
ATOM   8595  N  ND2  . ASN A 1 561 ? 12.348  13.423  36.382  1   34.765  ? 567  ASN A ND2  1 ? 
ATOM   8596  H  H    . ASN A 1 561 ? 8.694   13.222  34.955  1   38.033  ? 567  ASN A H    1 c 
ATOM   8597  H  HA   . ASN A 1 561 ? 9.766   15.795  34.673  1   38.381  ? 567  ASN A HA   1 c 
ATOM   8598  H  HB2  . ASN A 1 561 ? 11.068  13.307  34.233  1   38.457  ? 567  ASN A HB2  1 c 
ATOM   8599  H  HB3  . ASN A 1 561 ? 11.715  14.683  33.793  1   38.505  ? 567  ASN A HB3  1 c 
ATOM   8600  H  HD21 . ASN A 1 561 ? 12.619  13.473  37.225  1   36.522  ? 567  ASN A HD21 1 c 
ATOM   8601  H  HD22 . ASN A 1 561 ? 12.518  12.695  35.904  1   36.551  ? 567  ASN A HD22 1 c 
ATOM   8602  N  N    . PHE A 1 562 ? 9.507   16.059  32.212  1   37.808  ? 568  PHE A N    1 ? 
ATOM   8603  C  CA   . PHE A 1 562 ? 9.283   16.202  30.784  1   42.223  ? 568  PHE A CA   1 ? 
ATOM   8604  C  C    . PHE A 1 562 ? 10.506  16.905  30.189  1   42.981  ? 568  PHE A C    1 ? 
ATOM   8605  O  O    . PHE A 1 562 ? 10.884  17.954  30.681  1   44.99   ? 568  PHE A O    1 ? 
ATOM   8606  C  CB   . PHE A 1 562 ? 7.989   16.991  30.515  1   42.152  ? 568  PHE A CB   1 ? 
ATOM   8607  C  CG   . PHE A 1 562 ? 6.699   16.363  31.02   1   43.746  ? 568  PHE A CG   1 ? 
ATOM   8608  C  CD1  . PHE A 1 562 ? 6.296   16.538  32.344  1   47.81   ? 568  PHE A CD1  1 ? 
ATOM   8609  C  CD2  . PHE A 1 562 ? 5.886   15.616  30.173  1   41.589  ? 568  PHE A CD2  1 ? 
ATOM   8610  C  CE1  . PHE A 1 562 ? 5.136   15.947  32.82   1   41.034  ? 568  PHE A CE1  1 ? 
ATOM   8611  C  CE2  . PHE A 1 562 ? 4.714   15.037  30.643  1   41.139  ? 568  PHE A CE2  1 ? 
ATOM   8612  C  CZ   . PHE A 1 562 ? 4.342   15.206  31.968  1   45.51   ? 568  PHE A CZ   1 ? 
ATOM   8613  H  H    . PHE A 1 562 ? 9.802   16.786  32.682  1   38.781  ? 568  PHE A H    1 c 
ATOM   8614  H  HA   . PHE A 1 562 ? 9.198   15.301  30.38   1   41.461  ? 568  PHE A HA   1 c 
ATOM   8615  H  HB2  . PHE A 1 562 ? 8.082   17.88   30.924  1   42.531  ? 568  PHE A HB2  1 c 
ATOM   8616  H  HB3  . PHE A 1 562 ? 7.911   17.126  29.547  1   42.483  ? 568  PHE A HB3  1 c 
ATOM   8617  H  HD1  . PHE A 1 562 ? 6.842   17.035  32.933  1   45.127  ? 568  PHE A HD1  1 c 
ATOM   8618  H  HD2  . PHE A 1 562 ? 6.142   15.49   29.274  1   42.003  ? 568  PHE A HD2  1 c 
ATOM   8619  H  HE1  . PHE A 1 562 ? 4.877   16.07   33.718  1   43.573  ? 568  PHE A HE1  1 c 
ATOM   8620  H  HE2  . PHE A 1 562 ? 4.173   14.527  30.061  1   42.252  ? 568  PHE A HE2  1 c 
ATOM   8621  H  HZ   . PHE A 1 562 ? 3.542   14.819  32.287  1   43.403  ? 568  PHE A HZ   1 c 
ATOM   8622  N  N    . LEU A 1 563 ? 11.105  16.332  29.137  1   41.652  ? 569  LEU A N    1 ? 
ATOM   8623  C  CA   . LEU A 1 563 ? 12.198  16.958  28.41   1   41.771  ? 569  LEU A CA   1 ? 
ATOM   8624  C  C    . LEU A 1 563 ? 11.631  17.815  27.291  1   36.701  ? 569  LEU A C    1 ? 
ATOM   8625  O  O    . LEU A 1 563 ? 10.758  17.346  26.574  1   38.631  ? 569  LEU A O    1 ? 
ATOM   8626  C  CB   . LEU A 1 563 ? 13.103  15.862  27.826  1   41.524  ? 569  LEU A CB   1 ? 
ATOM   8627  C  CG   . LEU A 1 563 ? 14.568  16.252  27.565  1   42.569  ? 569  LEU A CG   1 ? 
ATOM   8628  C  CD1  . LEU A 1 563 ? 15.283  16.667  28.839  1   42.923  ? 569  LEU A CD1  1 ? 
ATOM   8629  C  CD2  . LEU A 1 563 ? 15.378  15.142  26.924  1   44.057  ? 569  LEU A CD2  1 ? 
ATOM   8630  H  H    . LEU A 1 563 ? 10.813  15.512  28.859  1   41.984  ? 569  LEU A H    1 c 
ATOM   8631  H  HA   . LEU A 1 563 ? 12.716  17.526  29.033  1   40.764  ? 569  LEU A HA   1 c 
ATOM   8632  H  HB2  . LEU A 1 563 ? 13.093  15.095  28.445  1   41.79   ? 569  LEU A HB2  1 c 
ATOM   8633  H  HB3  . LEU A 1 563 ? 12.708  15.56   26.978  1   41.687  ? 569  LEU A HB3  1 c 
ATOM   8634  H  HG   . LEU A 1 563 ? 14.573  17.027  26.947  1   42.715  ? 569  LEU A HG   1 c 
ATOM   8635  H  HD11 . LEU A 1 563 ? 14.898  17.493  29.176  1   42.799  ? 569  LEU A HD11 1 c 
ATOM   8636  H  HD12 . LEU A 1 563 ? 16.227  16.806  28.652  1   42.825  ? 569  LEU A HD12 1 c 
ATOM   8637  H  HD13 . LEU A 1 563 ? 15.186  15.969  29.509  1   42.816  ? 569  LEU A HD13 1 c 
ATOM   8638  H  HD21 . LEU A 1 563 ? 14.955  14.87   26.092  1   43.517  ? 569  LEU A HD21 1 c 
ATOM   8639  H  HD22 . LEU A 1 563 ? 15.421  14.382  27.527  1   43.585  ? 569  LEU A HD22 1 c 
ATOM   8640  H  HD23 . LEU A 1 563 ? 16.277  15.461  26.741  1   43.574  ? 569  LEU A HD23 1 c 
ATOM   8641  N  N    . THR A 1 564 ? 12.165  19.034  27.105  1   38.881  ? 570  THR A N    1 ? 
ATOM   8642  C  CA   . THR A 1 564 ? 11.742  19.904  26.01   1   36.253  ? 570  THR A CA   1 ? 
ATOM   8643  C  C    . THR A 1 564 ? 12.828  20.939  25.665  1   36.912  ? 570  THR A C    1 ? 
ATOM   8644  O  O    . THR A 1 564 ? 13.955  20.905  26.18   1   33.971  ? 570  THR A O    1 ? 
ATOM   8645  C  CB   . THR A 1 564 ? 10.442  20.596  26.431  1   35.756  ? 570  THR A CB   1 ? 
ATOM   8646  O  OG1  . THR A 1 564 ? 9.922   21.343  25.34   1   31.877  ? 570  THR A OG1  1 ? 
ATOM   8647  C  CG2  . THR A 1 564 ? 10.661  21.598  27.55   1   33.144  ? 570  THR A CG2  1 ? 
ATOM   8648  H  H    . THR A 1 564 ? 12.811  19.332  27.678  1   37.796  ? 570  THR A H    1 c 
ATOM   8649  H  HA   . THR A 1 564 ? 11.566  19.352  25.218  1   36.787  ? 570  THR A HA   1 c 
ATOM   8650  H  HB   . THR A 1 564 ? 9.777   19.924  26.715  1   34.572  ? 570  THR A HB   1 c 
ATOM   8651  H  HG1  . THR A 1 564 ? 10.495  21.925  25.083  0   31.68   ? 570  THR A HG1  1 c 
ATOM   8652  H  HG21 . THR A 1 564 ? 9.801   21.919  27.87   1   33.912  ? 570  THR A HG21 1 c 
ATOM   8653  H  HG22 . THR A 1 564 ? 11.181  22.349  27.219  1   33.94   ? 570  THR A HG22 1 c 
ATOM   8654  H  HG23 . THR A 1 564 ? 11.138  21.171  28.281  1   33.931  ? 570  THR A HG23 1 c 
ATOM   8655  N  N    . TRP A 1 565 ? 12.453  21.918  24.834  1   38.625  ? 571  TRP A N    1 ? 
ATOM   8656  C  CA   . TRP A 1 565 ? 13.402  22.924  24.363  1   39.283  ? 571  TRP A CA   1 ? 
ATOM   8657  C  C    . TRP A 1 565 ? 12.631  24.16   23.918  1   38.962  ? 571  TRP A C    1 ? 
ATOM   8658  O  O    . TRP A 1 565 ? 11.417  24.154  23.996  1   40.696  ? 571  TRP A O    1 ? 
ATOM   8659  C  CB   . TRP A 1 565 ? 14.336  22.366  23.27   1   36.542  ? 571  TRP A CB   1 ? 
ATOM   8660  C  CG   . TRP A 1 565 ? 13.727  21.964  21.955  1   33.777  ? 571  TRP A CG   1 ? 
ATOM   8661  C  CD1  . TRP A 1 565 ? 12.513  21.363  21.761  1   37.934  ? 571  TRP A CD1  1 ? 
ATOM   8662  C  CD2  . TRP A 1 565 ? 14.345  22.047  20.633  1   34.128  ? 571  TRP A CD2  1 ? 
ATOM   8663  N  NE1  . TRP A 1 565 ? 12.333  21.086  20.428  1   38.685  ? 571  TRP A NE1  1 ? 
ATOM   8664  C  CE2  . TRP A 1 565 ? 13.425  21.506  19.711  1   35.392  ? 571  TRP A CE2  1 ? 
ATOM   8665  C  CE3  . TRP A 1 565 ? 15.556  22.54   20.133  1   34.995  ? 571  TRP A CE3  1 ? 
ATOM   8666  C  CZ2  . TRP A 1 565 ? 13.696  21.433  18.345  1   36.827  ? 571  TRP A CZ2  1 ? 
ATOM   8667  C  CZ3  . TRP A 1 565 ? 15.831  22.47   18.782  1   36.14   ? 571  TRP A CZ3  1 ? 
ATOM   8668  C  CH2  . TRP A 1 565 ? 14.914  21.912  17.9    1   38.468  ? 571  TRP A CH2  1 ? 
ATOM   8669  H  H    . TRP A 1 565 ? 11.586  21.962  24.55   1   38.316  ? 571  TRP A H    1 c 
ATOM   8670  H  HA   . TRP A 1 565 ? 13.97   23.186  25.134  1   38.59   ? 571  TRP A HA   1 c 
ATOM   8671  H  HB2  . TRP A 1 565 ? 15.033  23.033  23.096  1   36.546  ? 571  TRP A HB2  1 c 
ATOM   8672  H  HB3  . TRP A 1 565 ? 14.804  21.588  23.642  1   36.487  ? 571  TRP A HB3  1 c 
ATOM   8673  H  HD1  . TRP A 1 565 ? 11.887  21.157  22.435  1   37.108  ? 571  TRP A HD1  1 c 
ATOM   8674  H  HE1  . TRP A 1 565 ? 11.617  20.722  20.086  1   37.637  ? 571  TRP A HE1  1 c 
ATOM   8675  H  HE3  . TRP A 1 565 ? 16.187  22.915  20.723  1   35.116  ? 571  TRP A HE3  1 c 
ATOM   8676  H  HZ2  . TRP A 1 565 ? 13.075  21.051  17.748  1   36.845  ? 571  TRP A HZ2  1 c 
ATOM   8677  H  HZ3  . TRP A 1 565 ? 16.652  22.801  18.455  1   36.378  ? 571  TRP A HZ3  1 c 
ATOM   8678  H  HH2  . TRP A 1 565 ? 15.115  21.88   16.981  1   37.476  ? 571  TRP A HH2  1 c 
ATOM   8679  N  N    . GLY A 1 566 ? 13.328  25.189  23.406  1   46.612  ? 572  GLY A N    1 ? 
ATOM   8680  C  CA   . GLY A 1 566 ? 12.704  26.444  23.001  1   43.862  ? 572  GLY A CA   1 ? 
ATOM   8681  C  C    . GLY A 1 566 ? 12.476  27.346  24.216  1   45.168  ? 572  GLY A C    1 ? 
ATOM   8682  O  O    . GLY A 1 566 ? 13.277  27.334  25.138  1   47.485  ? 572  GLY A O    1 ? 
ATOM   8683  H  H    . GLY A 1 566 ? 14.234  25.106  23.314  1   43.901  ? 572  GLY A H    1 c 
ATOM   8684  H  HA2  . GLY A 1 566 ? 13.288  26.903  22.353  1   44.795  ? 572  GLY A HA2  1 c 
ATOM   8685  H  HA3  . GLY A 1 566 ? 11.844  26.255  22.559  1   44.812  ? 572  GLY A HA3  1 c 
ATOM   8686  N  N    . LYS A 1 567 ? 11.333  28.038  24.261  1   47.707  ? 573  LYS A N    1 ? 
ATOM   8687  C  CA   . LYS A 1 567 ? 10.956  28.837  25.418  1   53.3    ? 573  LYS A CA   1 ? 
ATOM   8688  C  C    . LYS A 1 567 ? 9.907   28.101  26.242  1   49.623  ? 573  LYS A C    1 ? 
ATOM   8689  O  O    . LYS A 1 567 ? 8.918   27.626  25.696  1   48.581  ? 573  LYS A O    1 ? 
ATOM   8690  C  CB   . LYS A 1 567 ? 10.388  30.198  25.009  1   60.26   ? 573  LYS A CB   1 ? 
ATOM   8691  C  CG   . LYS A 1 567 ? 11.311  30.948  24.075  1   79.86   ? 573  LYS A CG   1 ? 
ATOM   8692  C  CD   . LYS A 1 567 ? 11.103  32.457  24.048  1   94.115  ? 573  LYS A CD   1 ? 
ATOM   8693  C  CE   . LYS A 1 567 ? 12.087  33.089  23.112  1   107.162 ? 573  LYS A CE   1 ? 
ATOM   8694  N  NZ   . LYS A 1 567 ? 12.635  34.348  23.63   1   118.338 ? 573  LYS A NZ   1 ? 
ATOM   8695  H  H    . LYS A 1 567 ? 10.767  28.013  23.543  1   48.222  ? 573  LYS A H    1 c 
ATOM   8696  H  HA   . LYS A 1 567 ? 11.76   28.986  25.975  1   52.528  ? 573  LYS A HA   1 c 
ATOM   8697  H  HB2  . LYS A 1 567 ? 9.523   30.069  24.564  1   62.486  ? 573  LYS A HB2  1 c 
ATOM   8698  H  HB3  . LYS A 1 567 ? 10.239  30.741  25.812  1   62.549  ? 573  LYS A HB3  1 c 
ATOM   8699  H  HG2  . LYS A 1 567 ? 12.237  30.761  24.341  1   77.659  ? 573  LYS A HG2  1 c 
ATOM   8700  H  HG3  . LYS A 1 567 ? 11.186  30.595  23.168  1   77.661  ? 573  LYS A HG3  1 c 
ATOM   8701  H  HD2  . LYS A 1 567 ? 10.19   32.658  23.747  1   93.501  ? 573  LYS A HD2  1 c 
ATOM   8702  H  HD3  . LYS A 1 567 ? 11.225  32.822  24.952  1   93.718  ? 573  LYS A HD3  1 c 
ATOM   8703  H  HE2  . LYS A 1 567 ? 12.82   32.474  22.936  1   105.607 ? 573  LYS A HE2  1 c 
ATOM   8704  H  HE3  . LYS A 1 567 ? 11.64   33.267  22.266  1   106.305 ? 573  LYS A HE3  1 c 
ATOM   8705  H  HZ1  . LYS A 1 567 ? 12.821  34.267  24.515  1   114.466 ? 573  LYS A HZ1  1 c 
ATOM   8706  H  HZ2  . LYS A 1 567 ? 12.032  35.017  23.512  1   114.705 ? 573  LYS A HZ2  1 c 
ATOM   8707  H  HZ3  . LYS A 1 567 ? 13.4    34.554  23.194  1   114.704 ? 573  LYS A HZ3  1 c 
ATOM   8708  N  N    . VAL A 1 568 ? 10.138  28.059  27.561  1   49.68   ? 574  VAL A N    1 ? 
ATOM   8709  C  CA   . VAL A 1 568 ? 9.33    27.32   28.516  1   48.671  ? 574  VAL A CA   1 ? 
ATOM   8710  C  C    . VAL A 1 568 ? 8.87    28.294  29.597  1   48.039  ? 574  VAL A C    1 ? 
ATOM   8711  O  O    . VAL A 1 568 ? 9.689   28.964  30.202  1   49.985  ? 574  VAL A O    1 ? 
ATOM   8712  C  CB   . VAL A 1 568 ? 10.148  26.181  29.145  1   50.247  ? 574  VAL A CB   1 ? 
ATOM   8713  C  CG1  . VAL A 1 568 ? 9.382   25.515  30.285  1   45.212  ? 574  VAL A CG1  1 ? 
ATOM   8714  C  CG2  . VAL A 1 568 ? 10.611  25.162  28.106  1   44.907  ? 574  VAL A CG2  1 ? 
ATOM   8715  H  H    . VAL A 1 568 ? 10.853  28.528  27.884  1   49.48   ? 574  VAL A H    1 c 
ATOM   8716  H  HA   . VAL A 1 568 ? 8.552   26.946  28.062  1   49.054  ? 574  VAL A HA   1 c 
ATOM   8717  H  HB   . VAL A 1 568 ? 10.956  26.59   29.534  1   47.959  ? 574  VAL A HB   1 c 
ATOM   8718  H  HG11 . VAL A 1 568 ? 8.482   25.297  29.989  1   46.64   ? 574  VAL A HG11 1 c 
ATOM   8719  H  HG12 . VAL A 1 568 ? 9.335   26.119  31.045  1   46.644  ? 574  VAL A HG12 1 c 
ATOM   8720  H  HG13 . VAL A 1 568 ? 9.841   24.699  30.551  1   46.639  ? 574  VAL A HG13 1 c 
ATOM   8721  H  HG21 . VAL A 1 568 ? 11.105  24.45   28.547  1   46.421  ? 574  VAL A HG21 1 c 
ATOM   8722  H  HG22 . VAL A 1 568 ? 11.186  25.598  27.455  1   46.433  ? 574  VAL A HG22 1 c 
ATOM   8723  H  HG23 . VAL A 1 568 ? 9.838   24.785  27.653  1   46.42   ? 574  VAL A HG23 1 c 
ATOM   8724  N  N    . ASP A 1 569 ? 7.561   28.401  29.797  1   49.402  ? 575  ASP A N    1 ? 
ATOM   8725  C  CA   . ASP A 1 569 ? 6.985   29.41   30.67   1   48.417  ? 575  ASP A CA   1 ? 
ATOM   8726  C  C    . ASP A 1 569 ? 6.128   28.718  31.735  1   53.258  ? 575  ASP A C    1 ? 
ATOM   8727  O  O    . ASP A 1 569 ? 5.059   28.172  31.424  1   47.002  ? 575  ASP A O    1 ? 
ATOM   8728  C  CB   . ASP A 1 569 ? 6.206   30.416  29.84   1   50.724  ? 575  ASP A CB   1 ? 
ATOM   8729  C  CG   . ASP A 1 569 ? 5.408   31.462  30.61   1   57.64   ? 575  ASP A CG   1 ? 
ATOM   8730  O  OD1  . ASP A 1 569 ? 5.567   31.528  31.844  1   54.255  ? 575  ASP A OD1  1 ? 
ATOM   8731  O  OD2  . ASP A 1 569 ? 4.606   32.183  29.965  1   59.167  ? 575  ASP A OD2  1 ? 
ATOM   8732  H  H    . ASP A 1 569 ? 6.998   27.818  29.375  1   48.852  ? 575  ASP A H    1 c 
ATOM   8733  H  HA   . ASP A 1 569 ? 7.715   29.893  31.114  1   49.98   ? 575  ASP A HA   1 c 
ATOM   8734  H  HB2  . ASP A 1 569 ? 6.836   30.888  29.256  1   51.684  ? 575  ASP A HB2  1 c 
ATOM   8735  H  HB3  . ASP A 1 569 ? 5.582   29.924  29.267  1   51.702  ? 575  ASP A HB3  1 c 
ATOM   8736  N  N    . ILE A 1 570 ? 6.598   28.777  32.992  1   59.287  ? 576  ILE A N    1 ? 
ATOM   8737  C  CA   . ILE A 1 570 ? 5.904   28.187  34.136  1   55.152  ? 576  ILE A CA   1 ? 
ATOM   8738  C  C    . ILE A 1 570 ? 5.315   29.256  35.057  1   59.38   ? 576  ILE A C    1 ? 
ATOM   8739  O  O    . ILE A 1 570 ? 5.053   28.953  36.209  1   55.918  ? 576  ILE A O    1 ? 
ATOM   8740  C  CB   . ILE A 1 570 ? 6.856   27.312  34.963  1   53.256  ? 576  ILE A CB   1 ? 
ATOM   8741  C  CG1  . ILE A 1 570 ? 8.045   28.132  35.46   1   56.591  ? 576  ILE A CG1  1 ? 
ATOM   8742  C  CG2  . ILE A 1 570 ? 7.286   26.073  34.18   1   52.52   ? 576  ILE A CG2  1 ? 
ATOM   8743  C  CD1  . ILE A 1 570 ? 8.82    27.489  36.594  1   62.948  ? 576  ILE A CD1  1 ? 
ATOM   8744  H  H    . ILE A 1 570 ? 7.384   29.218  33.142  1   56.731  ? 576  ILE A H    1 c 
ATOM   8745  H  HA   . ILE A 1 570 ? 5.177   27.624  33.807  1   56.209  ? 576  ILE A HA   1 c 
ATOM   8746  H  HB   . ILE A 1 570 ? 6.365   27.004  35.75   1   54.113  ? 576  ILE A HB   1 c 
ATOM   8747  H  HG12 . ILE A 1 570 ? 8.657   28.279  34.711  1   57.206  ? 576  ILE A HG12 1 c 
ATOM   8748  H  HG13 . ILE A 1 570 ? 7.725   29.007  35.759  1   57.203  ? 576  ILE A HG13 1 c 
ATOM   8749  H  HG21 . ILE A 1 570 ? 7.837   25.505  34.744  1   52.854  ? 576  ILE A HG21 1 c 
ATOM   8750  H  HG22 . ILE A 1 570 ? 7.796   26.342  33.397  1   52.794  ? 576  ILE A HG22 1 c 
ATOM   8751  H  HG23 . ILE A 1 570 ? 6.499   25.578  33.896  1   52.769  ? 576  ILE A HG23 1 c 
ATOM   8752  H  HD11 . ILE A 1 570 ? 8.268   27.484  37.399  1   60.958  ? 576  ILE A HD11 1 c 
ATOM   8753  H  HD12 . ILE A 1 570 ? 9.633   28.001  36.764  1   60.96   ? 576  ILE A HD12 1 c 
ATOM   8754  H  HD13 . ILE A 1 570 ? 9.058   26.572  36.361  1   60.838  ? 576  ILE A HD13 1 c 
ATOM   8755  N  N    . SER A 1 571 ? 5.107   30.487  34.577  1   60.139  ? 577  SER A N    1 ? 
ATOM   8756  C  CA   . SER A 1 571 ? 4.624   31.56   35.439  1   57.269  ? 577  SER A CA   1 ? 
ATOM   8757  C  C    . SER A 1 571 ? 3.232   31.218  35.962  1   58.241  ? 577  SER A C    1 ? 
ATOM   8758  O  O    . SER A 1 571 ? 3.034   31.213  37.17   1   72.519  ? 577  SER A O    1 ? 
ATOM   8759  C  CB   . SER A 1 571 ? 4.615   32.895  34.733  1   53.552  ? 577  SER A CB   1 ? 
ATOM   8760  O  OG   . SER A 1 571 ? 3.761   32.817  33.599  1   52.133  ? 577  SER A OG   1 ? 
ATOM   8761  H  H    . SER A 1 571 ? 5.263   30.665  33.694  1   59.203  ? 577  SER A H    1 c 
ATOM   8762  H  HA   . SER A 1 571 ? 5.236   31.626  36.216  1   57.362  ? 577  SER A HA   1 c 
ATOM   8763  H  HB2  . SER A 1 571 ? 4.294   33.586  35.342  1   54.022  ? 577  SER A HB2  1 c 
ATOM   8764  H  HB3  . SER A 1 571 ? 5.521   33.122  34.449  1   54.023  ? 577  SER A HB3  1 c 
ATOM   8765  H  HG   . SER A 1 571 ? 3.735   33.615  33.262  0   53.7    ? 577  SER A HG   1 c 
ATOM   8766  N  N    . VAL A 1 572 ? 2.288   30.93   35.053  1   53.078  ? 578  VAL A N    1 ? 
ATOM   8767  C  CA   . VAL A 1 572 ? 0.941   30.477  35.397  1   54.477  ? 578  VAL A CA   1 ? 
ATOM   8768  C  C    . VAL A 1 572 ? 0.99    29.134  36.14   1   60.099  ? 578  VAL A C    1 ? 
ATOM   8769  O  O    . VAL A 1 572 ? 1.602   28.188  35.645  1   65.814  ? 578  VAL A O    1 ? 
ATOM   8770  C  CB   . VAL A 1 572 ? 0.088   30.373  34.11   1   56.092  ? 578  VAL A CB   1 ? 
ATOM   8771  C  CG1  . VAL A 1 572 ? -1.243  29.671  34.343  1   61.308  ? 578  VAL A CG1  1 ? 
ATOM   8772  C  CG2  . VAL A 1 572 ? -0.14   31.725  33.444  1   53.63   ? 578  VAL A CG2  1 ? 
ATOM   8773  H  H    . VAL A 1 572 ? 2.501   31.018  34.168  1   54.643  ? 578  VAL A H    1 c 
ATOM   8774  H  HA   . VAL A 1 572 ? 0.535   31.145  35.979  1   55.575  ? 578  VAL A HA   1 c 
ATOM   8775  H  HB   . VAL A 1 572 ? 0.598   29.819  33.474  1   56.196  ? 578  VAL A HB   1 c 
ATOM   8776  H  HG11 . VAL A 1 572 ? -1.696  30.079  35.1    1   59.699  ? 578  VAL A HG11 1 c 
ATOM   8777  H  HG12 . VAL A 1 572 ? -1.089  28.73   34.527  1   59.686  ? 578  VAL A HG12 1 c 
ATOM   8778  H  HG13 . VAL A 1 572 ? -1.799  29.757  33.55   1   59.641  ? 578  VAL A HG13 1 c 
ATOM   8779  H  HG21 . VAL A 1 572 ? -0.698  31.609  32.656  1   54.378  ? 578  VAL A HG21 1 c 
ATOM   8780  H  HG22 . VAL A 1 572 ? 0.714   32.106  33.18   1   54.347  ? 578  VAL A HG22 1 c 
ATOM   8781  H  HG23 . VAL A 1 572 ? -0.582  32.324  34.068  1   54.351  ? 578  VAL A HG23 1 c 
ATOM   8782  N  N    . PRO A 1 573 ? 0.393   28.981  37.354  1   60.243  ? 579  PRO A N    1 ? 
ATOM   8783  C  CA   . PRO A 1 573 ? 0.305   27.671  38.014  1   54.07   ? 579  PRO A CA   1 ? 
ATOM   8784  C  C    . PRO A 1 573 ? -0.705  26.738  37.359  1   53.224  ? 579  PRO A C    1 ? 
ATOM   8785  O  O    . PRO A 1 573 ? -1.723  27.175  36.819  1   58.996  ? 579  PRO A O    1 ? 
ATOM   8786  C  CB   . PRO A 1 573 ? -0.076  28.001  39.473  1   66.48   ? 579  PRO A CB   1 ? 
ATOM   8787  C  CG   . PRO A 1 573 ? 0.263   29.481  39.602  1   68.429  ? 579  PRO A CG   1 ? 
ATOM   8788  C  CD   . PRO A 1 573 ? -0.095  30.061  38.227  1   62.957  ? 579  PRO A CD   1 ? 
ATOM   8789  H  HA   . PRO A 1 573 ? 1.201   27.25   38      1   57.095  ? 579  PRO A HA   1 c 
ATOM   8790  H  HB2  . PRO A 1 573 ? -1.036  27.844  39.633  1   63.847  ? 579  PRO A HB2  1 c 
ATOM   8791  H  HB3  . PRO A 1 573 ? 0.451   27.461  40.107  1   63.9    ? 579  PRO A HB3  1 c 
ATOM   8792  H  HG2  . PRO A 1 573 ? -0.268  29.903  40.31   1   66.731  ? 579  PRO A HG2  1 c 
ATOM   8793  H  HG3  . PRO A 1 573 ? 1.215   29.608  39.799  1   66.732  ? 579  PRO A HG3  1 c 
ATOM   8794  H  HD2  . PRO A 1 573 ? -1.065  30.194  38.133  1   63.448  ? 579  PRO A HD2  1 c 
ATOM   8795  H  HD3  . PRO A 1 573 ? 0.378   30.906  38.063  1   63.357  ? 579  PRO A HD3  1 c 
ATOM   8796  N  N    . GLY A 1 574 ? -0.394  25.438  37.354  1   48.624  ? 580  GLY A N    1 ? 
ATOM   8797  C  CA   . GLY A 1 574 ? -1.263  24.502  36.649  1   52.087  ? 580  GLY A CA   1 ? 
ATOM   8798  C  C    . GLY A 1 574 ? -0.923  24.316  35.161  1   43.734  ? 580  GLY A C    1 ? 
ATOM   8799  O  O    . GLY A 1 574 ? -1.47   23.411  34.547  1   42.644  ? 580  GLY A O    1 ? 
ATOM   8800  H  H    . GLY A 1 574 ? 0.345   25.13   37.794  1   50.527  ? 580  GLY A H    1 c 
ATOM   8801  H  HA2  . GLY A 1 574 ? -1.207  23.626  37.099  1   49.298  ? 580  GLY A HA2  1 c 
ATOM   8802  H  HA3  . GLY A 1 574 ? -2.196  24.812  36.728  1   49.364  ? 580  GLY A HA3  1 c 
ATOM   8803  N  N    . LYS A 1 575 ? 0.01    25.11   34.604  1   47.596  ? 581  LYS A N    1 ? 
ATOM   8804  C  CA   . LYS A 1 575 ? 0.249   25.205  33.165  1   46.955  ? 581  LYS A CA   1 ? 
ATOM   8805  C  C    . LYS A 1 575 ? 1.729   25.456  32.853  1   51.859  ? 581  LYS A C    1 ? 
ATOM   8806  O  O    . LYS A 1 575 ? 2.384   26.312  33.467  1   49.549  ? 581  LYS A O    1 ? 
ATOM   8807  C  CB   . LYS A 1 575 ? -0.475  26.383  32.496  1   57.904  ? 581  LYS A CB   1 ? 
ATOM   8808  C  CG   . LYS A 1 575 ? -1.986  26.284  32.432  1   65.296  ? 581  LYS A CG   1 ? 
ATOM   8809  C  CD   . LYS A 1 575 ? -2.688  27.287  31.514  1   82.278  ? 581  LYS A CD   1 ? 
ATOM   8810  C  CE   . LYS A 1 575 ? -4.141  26.902  31.311  1   93.137  ? 581  LYS A CE   1 ? 
ATOM   8811  N  NZ   . LYS A 1 575 ? -4.9    27.823  30.462  1   97.992  ? 581  LYS A NZ   1 ? 
ATOM   8812  H  H    . LYS A 1 575 ? 0.535   25.614  35.156  1   46.62   ? 581  LYS A H    1 c 
ATOM   8813  H  HA   . LYS A 1 575 ? -0.037  24.36   32.739  1   49.663  ? 581  LYS A HA   1 c 
ATOM   8814  H  HB2  . LYS A 1 575 ? -0.243  27.204  32.98   1   56.755  ? 581  LYS A HB2  1 c 
ATOM   8815  H  HB3  . LYS A 1 575 ? -0.137  26.476  31.579  1   56.74   ? 581  LYS A HB3  1 c 
ATOM   8816  H  HG2  . LYS A 1 575 ? -2.22   25.376  32.138  1   67.199  ? 581  LYS A HG2  1 c 
ATOM   8817  H  HG3  . LYS A 1 575 ? -2.338  26.394  33.342  1   66.992  ? 581  LYS A HG3  1 c 
ATOM   8818  H  HD2  . LYS A 1 575 ? -2.642  28.183  31.913  1   80.296  ? 581  LYS A HD2  1 c 
ATOM   8819  H  HD3  . LYS A 1 575 ? -2.233  27.306  30.645  1   80.182  ? 581  LYS A HD3  1 c 
ATOM   8820  H  HE2  . LYS A 1 575 ? -4.179  26.013  30.914  1   91.475  ? 581  LYS A HE2  1 c 
ATOM   8821  H  HE3  . LYS A 1 575 ? -4.577  26.854  32.181  1   91.622  ? 581  LYS A HE3  1 c 
ATOM   8822  H  HZ1  . LYS A 1 575 ? -4.53   27.853  29.636  1   96.471  ? 581  LYS A HZ1  1 c 
ATOM   8823  H  HZ2  . LYS A 1 575 ? -4.889  28.653  30.824  1   96.471  ? 581  LYS A HZ2  1 c 
ATOM   8824  H  HZ3  . LYS A 1 575 ? -5.758  27.54   30.393  1   96.471  ? 581  LYS A HZ3  1 c 
ATOM   8825  N  N    . VAL A 1 576 ? 2.225   24.716  31.846  1   46.403  ? 582  VAL A N    1 ? 
ATOM   8826  C  CA   . VAL A 1 576 ? 3.528   24.941  31.243  1   46.504  ? 582  VAL A CA   1 ? 
ATOM   8827  C  C    . VAL A 1 576 ? 3.285   25.198  29.759  1   46.297  ? 582  VAL A C    1 ? 
ATOM   8828  O  O    . VAL A 1 576 ? 2.749   24.336  29.058  1   39.419  ? 582  VAL A O    1 ? 
ATOM   8829  C  CB   . VAL A 1 576 ? 4.483   23.746  31.438  1   44.267  ? 582  VAL A CB   1 ? 
ATOM   8830  C  CG1  . VAL A 1 576 ? 5.92    24.081  31.059  1   45.204  ? 582  VAL A CG1  1 ? 
ATOM   8831  C  CG2  . VAL A 1 576 ? 4.432   23.217  32.855  1   41.558  ? 582  VAL A CG2  1 ? 
ATOM   8832  H  H    . VAL A 1 576 ? 1.717   24.028  31.522  1   47.675  ? 582  VAL A H    1 c 
ATOM   8833  H  HA   . VAL A 1 576 ? 3.93    25.735  31.643  1   46.098  ? 582  VAL A HA   1 c 
ATOM   8834  H  HB   . VAL A 1 576 ? 4.175   23.026  30.839  1   44.335  ? 582  VAL A HB   1 c 
ATOM   8835  H  HG11 . VAL A 1 576 ? 6.159   24.948  31.431  1   44.924  ? 582  VAL A HG11 1 c 
ATOM   8836  H  HG12 . VAL A 1 576 ? 6.002   24.111  30.091  1   44.922  ? 582  VAL A HG12 1 c 
ATOM   8837  H  HG13 . VAL A 1 576 ? 6.517   23.404  31.414  1   44.882  ? 582  VAL A HG13 1 c 
ATOM   8838  H  HG21 . VAL A 1 576 ? 5.097   22.516  32.964  1   42.384  ? 582  VAL A HG21 1 c 
ATOM   8839  H  HG22 . VAL A 1 576 ? 3.549   22.853  33.036  1   42.374  ? 582  VAL A HG22 1 c 
ATOM   8840  H  HG23 . VAL A 1 576 ? 4.619   23.939  33.478  1   42.357  ? 582  VAL A HG23 1 c 
ATOM   8841  N  N    . THR A 1 577 ? 3.646   26.404  29.311  1   47.023  ? 583  THR A N    1 ? 
ATOM   8842  C  CA   . THR A 1 577 ? 3.632   26.719  27.899  1   51.634  ? 583  THR A CA   1 ? 
ATOM   8843  C  C    . THR A 1 577 ? 5.006   26.433  27.296  1   49.386  ? 583  THR A C    1 ? 
ATOM   8844  O  O    . THR A 1 577 ? 6.045   26.806  27.848  1   52.713  ? 583  THR A O    1 ? 
ATOM   8845  C  CB   . THR A 1 577 ? 3.194   28.162  27.69   1   54.912  ? 583  THR A CB   1 ? 
ATOM   8846  O  OG1  . THR A 1 577 ? 1.863   28.228  28.18   1   54.906  ? 583  THR A OG1  1 ? 
ATOM   8847  C  CG2  . THR A 1 577 ? 3.103   28.526  26.224  1   59.81   ? 583  THR A CG2  1 ? 
ATOM   8848  H  H    . THR A 1 577 ? 3.906   27.049  29.904  1   47.87   ? 583  THR A H    1 c 
ATOM   8849  H  HA   . THR A 1 577 ? 2.973   26.137  27.463  1   50.679  ? 583  THR A HA   1 c 
ATOM   8850  H  HB   . THR A 1 577 ? 3.772   28.791  28.184  1   55.132  ? 583  THR A HB   1 c 
ATOM   8851  H  HG1  . THR A 1 577 ? 1.333   27.698  27.71   0   54.98   ? 583  THR A HG1  1 c 
ATOM   8852  H  HG21 . THR A 1 577 ? 2.804   29.446  26.138  1   58.647  ? 583  THR A HG21 1 c 
ATOM   8853  H  HG22 . THR A 1 577 ? 2.47    27.937  25.781  1   58.384  ? 583  THR A HG22 1 c 
ATOM   8854  H  HG23 . THR A 1 577 ? 3.977   28.433  25.809  1   58.345  ? 583  THR A HG23 1 c 
ATOM   8855  N  N    . ILE A 1 578 ? 4.986   25.74   26.156  1   44.113  ? 584  ILE A N    1 ? 
ATOM   8856  C  CA   . ILE A 1 578 ? 6.198   25.467  25.404  1   44.742  ? 584  ILE A CA   1 ? 
ATOM   8857  C  C    . ILE A 1 578 ? 6.047   26.093  24.022  1   40.124  ? 584  ILE A C    1 ? 
ATOM   8858  O  O    . ILE A 1 578 ? 5.131   25.739  23.283  1   38.957  ? 584  ILE A O    1 ? 
ATOM   8859  C  CB   . ILE A 1 578 ? 6.449   23.948  25.332  1   45.899  ? 584  ILE A CB   1 ? 
ATOM   8860  C  CG1  . ILE A 1 578 ? 6.543   23.303  26.724  1   40.993  ? 584  ILE A CG1  1 ? 
ATOM   8861  C  CG2  . ILE A 1 578 ? 7.682   23.622  24.501  1   45.399  ? 584  ILE A CG2  1 ? 
ATOM   8862  C  CD1  . ILE A 1 578 ? 6.351   21.801  26.69   1   38.498  ? 584  ILE A CD1  1 ? 
ATOM   8863  H  H    . ILE A 1 578 ? 4.19    25.426  25.835  1   45.547  ? 584  ILE A H    1 c 
ATOM   8864  H  HA   . ILE A 1 578 ? 6.953   25.884  25.859  1   44.022  ? 584  ILE A HA   1 c 
ATOM   8865  H  HB   . ILE A 1 578 ? 5.679   23.549  24.88   1   44.666  ? 584  ILE A HB   1 c 
ATOM   8866  H  HG12 . ILE A 1 578 ? 7.421   23.504  27.108  1   41.458  ? 584  ILE A HG12 1 c 
ATOM   8867  H  HG13 . ILE A 1 578 ? 5.862   23.696  27.306  1   41.495  ? 584  ILE A HG13 1 c 
ATOM   8868  H  HG21 . ILE A 1 578 ? 7.811   22.66   24.472  1   45.374  ? 584  ILE A HG21 1 c 
ATOM   8869  H  HG22 . ILE A 1 578 ? 8.463   24.04   24.9    1   45.511  ? 584  ILE A HG22 1 c 
ATOM   8870  H  HG23 . ILE A 1 578 ? 7.564   23.955  23.597  1   45.535  ? 584  ILE A HG23 1 c 
ATOM   8871  H  HD11 . ILE A 1 578 ? 5.502   21.591  26.258  1   39.236  ? 584  ILE A HD11 1 c 
ATOM   8872  H  HD12 . ILE A 1 578 ? 6.344   21.454  27.602  1   39.236  ? 584  ILE A HD12 1 c 
ATOM   8873  H  HD13 . ILE A 1 578 ? 7.079   21.384  26.192  1   39.288  ? 584  ILE A HD13 1 c 
ATOM   8874  N  N    . ASP A 1 579 ? 6.942   27.029  23.685  1   42.497  ? 585  ASP A N    1 ? 
ATOM   8875  C  CA   . ASP A 1 579 ? 7.019   27.575  22.329  1   47.702  ? 585  ASP A CA   1 ? 
ATOM   8876  C  C    . ASP A 1 579 ? 8.327   27.191  21.637  1   43.232  ? 585  ASP A C    1 ? 
ATOM   8877  O  O    . ASP A 1 579 ? 9.404   27.585  22.068  1   54.158  ? 585  ASP A O    1 ? 
ATOM   8878  C  CB   . ASP A 1 579 ? 6.974   29.092  22.279  1   47.719  ? 585  ASP A CB   1 ? 
ATOM   8879  C  CG   . ASP A 1 579 ? 5.648   29.751  22.627  1   59.827  ? 585  ASP A CG   1 ? 
ATOM   8880  O  OD1  . ASP A 1 579 ? 5.313   29.783  23.837  1   60.648  ? 585  ASP A OD1  1 ? 
ATOM   8881  O  OD2  . ASP A 1 579 ? 4.987   30.262  21.688  1   69.299  ? 585  ASP A OD2  1 ? 
ATOM   8882  H  H    . ASP A 1 579 ? 7.523   27.341  24.317  1   43.039  ? 585  ASP A H    1 c 
ATOM   8883  H  HA   . ASP A 1 579 ? 6.264   27.229  21.807  1   45.779  ? 585  ASP A HA   1 c 
ATOM   8884  H  HB2  . ASP A 1 579 ? 7.649   29.439  22.898  1   50.304  ? 585  ASP A HB2  1 c 
ATOM   8885  H  HB3  . ASP A 1 579 ? 7.222   29.383  21.376  1   50.336  ? 585  ASP A HB3  1 c 
ATOM   8886  N  N    . VAL A 1 580 ? 8.216   26.494  20.505  1   48.41   ? 586  VAL A N    1 ? 
ATOM   8887  C  CA   . VAL A 1 580 ? 9.38    26.056  19.752  1   44.932  ? 586  VAL A CA   1 ? 
ATOM   8888  C  C    . VAL A 1 580 ? 9.124   26.241  18.263  1   42.549  ? 586  VAL A C    1 ? 
ATOM   8889  O  O    . VAL A 1 580 ? 8.197   25.627  17.694  1   35.915  ? 586  VAL A O    1 ? 
ATOM   8890  C  CB   . VAL A 1 580 ? 9.707   24.572  19.979  1   49.533  ? 586  VAL A CB   1 ? 
ATOM   8891  C  CG1  . VAL A 1 580 ? 11.08   24.235  19.424  1   50.791  ? 586  VAL A CG1  1 ? 
ATOM   8892  C  CG2  . VAL A 1 580 ? 9.582   24.166  21.431  1   56.504  ? 586  VAL A CG2  1 ? 
ATOM   8893  H  H    . VAL A 1 580 ? 7.385   26.281  20.189  1   46.315  ? 586  VAL A H    1 c 
ATOM   8894  H  HA   . VAL A 1 580 ? 10.151  26.594  20.014  1   45.932  ? 586  VAL A HA   1 c 
ATOM   8895  H  HB   . VAL A 1 580 ? 9.044   24.046  19.472  1   49.967  ? 586  VAL A HB   1 c 
ATOM   8896  H  HG11 . VAL A 1 580 ? 11.745  24.823  19.82   1   50.326  ? 586  VAL A HG11 1 c 
ATOM   8897  H  HG12 . VAL A 1 580 ? 11.08   24.352  18.459  1   50.271  ? 586  VAL A HG12 1 c 
ATOM   8898  H  HG13 . VAL A 1 580 ? 11.297  23.314  19.635  1   50.243  ? 586  VAL A HG13 1 c 
ATOM   8899  H  HG21 . VAL A 1 580 ? 9.961   23.279  21.556  1   54.222  ? 586  VAL A HG21 1 c 
ATOM   8900  H  HG22 . VAL A 1 580 ? 8.645   24.154  21.685  1   54.174  ? 586  VAL A HG22 1 c 
ATOM   8901  H  HG23 . VAL A 1 580 ? 10.06   24.803  21.987  1   54.128  ? 586  VAL A HG23 1 c 
ATOM   8902  N  N    . GLN A 1 581 ? 10.028  26.992  17.629  1   40.772  ? 587  GLN A N    1 ? 
ATOM   8903  C  CA   . GLN A 1 581 ? 9.974   27.256  16.195  1   42.025  ? 587  GLN A CA   1 ? 
ATOM   8904  C  C    . GLN A 1 581 ? 8.558   27.587  15.714  1   39.946  ? 587  GLN A C    1 ? 
ATOM   8905  O  O    . GLN A 1 581 ? 8.115   27.059  14.68   1   40.724  ? 587  GLN A O    1 ? 
ATOM   8906  C  CB   . GLN A 1 581 ? 10.565  26.06   15.458  1   39.037  ? 587  GLN A CB   1 ? 
ATOM   8907  C  CG   . GLN A 1 581 ? 12.015  25.802  15.843  1   42.828  ? 587  GLN A CG   1 ? 
ATOM   8908  C  CD   . GLN A 1 581 ? 12.598  24.619  15.122  1   46.445  ? 587  GLN A CD   1 ? 
ATOM   8909  O  OE1  . GLN A 1 581 ? 12.034  24.121  14.145  1   49.573  ? 587  GLN A OE1  1 ? 
ATOM   8910  N  NE2  . GLN A 1 581 ? 13.715  24.129  15.625  1   52.653  ? 587  GLN A NE2  1 ? 
ATOM   8911  H  H    . GLN A 1 581 ? 10.712  27.361  18.111  1   41.534  ? 587  GLN A H    1 c 
ATOM   8912  H  HA   . GLN A 1 581 ? 10.551  28.041  16.009  1   40.834  ? 587  GLN A HA   1 c 
ATOM   8913  H  HB2  . GLN A 1 581 ? 10.032  25.264  15.661  1   40.593  ? 587  GLN A HB2  1 c 
ATOM   8914  H  HB3  . GLN A 1 581 ? 10.513  26.221  14.493  1   40.653  ? 587  GLN A HB3  1 c 
ATOM   8915  H  HG2  . GLN A 1 581 ? 12.552  26.597  15.637  1   42.749  ? 587  GLN A HG2  1 c 
ATOM   8916  H  HG3  . GLN A 1 581 ? 12.073  25.644  16.809  1   42.818  ? 587  GLN A HG3  1 c 
ATOM   8917  H  HE21 . GLN A 1 581 ? 14.093  23.419  15.252  1   50.619  ? 587  GLN A HE21 1 c 
ATOM   8918  H  HE22 . GLN A 1 581 ? 14.089  24.509  16.334  1   50.526  ? 587  GLN A HE22 1 c 
ATOM   8919  N  N    . GLY A 1 582 ? 7.874   28.465  16.466  1   37.344  ? 588  GLY A N    1 ? 
ATOM   8920  C  CA   . GLY A 1 582 ? 6.528   28.941  16.135  1   41.577  ? 588  GLY A CA   1 ? 
ATOM   8921  C  C    . GLY A 1 582 ? 5.422   27.905  16.401  1   45.569  ? 588  GLY A C    1 ? 
ATOM   8922  O  O    . GLY A 1 582 ? 4.254   28.144  16.089  1   39.14   ? 588  GLY A O    1 ? 
ATOM   8923  H  H    . GLY A 1 582 ? 8.269   28.79   17.223  1   38.928  ? 588  GLY A H    1 c 
ATOM   8924  H  HA2  . GLY A 1 582 ? 6.342   29.75   16.664  1   41.362  ? 588  GLY A HA2  1 c 
ATOM   8925  H  HA3  . GLY A 1 582 ? 6.509   29.197  15.183  1   41.359  ? 588  GLY A HA3  1 c 
ATOM   8926  N  N    . GLN A 1 583 ? 5.775   26.733  16.949  1   42.998  ? 589  GLN A N    1 ? 
ATOM   8927  C  CA   . GLN A 1 583 ? 4.769   25.81   17.467  1   46.484  ? 589  GLN A CA   1 ? 
ATOM   8928  C  C    . GLN A 1 583 ? 4.576   26.048  18.971  1   48.238  ? 589  GLN A C    1 ? 
ATOM   8929  O  O    . GLN A 1 583 ? 5.57    26.157  19.693  1   49.16   ? 589  GLN A O    1 ? 
ATOM   8930  C  CB   . GLN A 1 583 ? 5.299   24.404  17.22   1   48.448  ? 589  GLN A CB   1 ? 
ATOM   8931  C  CG   . GLN A 1 583 ? 4.312   23.438  16.591  1   62.014  ? 589  GLN A CG   1 ? 
ATOM   8932  C  CD   . GLN A 1 583 ? 3.592   23.978  15.371  1   56.218  ? 589  GLN A CD   1 ? 
ATOM   8933  O  OE1  . GLN A 1 583 ? 2.387   23.764  15.279  1   49.111  ? 589  GLN A OE1  1 ? 
ATOM   8934  N  NE2  . GLN A 1 583 ? 4.278   24.639  14.433  1   46.371  ? 589  GLN A NE2  1 ? 
ATOM   8935  H  H    . GLN A 1 583 ? 6.657   26.507  17.012  1   44.33   ? 589  GLN A H    1 c 
ATOM   8936  H  HA   . GLN A 1 583 ? 3.913   25.955  16.992  1   46.506  ? 589  GLN A HA   1 c 
ATOM   8937  H  HB2  . GLN A 1 583 ? 6.084   24.464  16.638  1   50.587  ? 589  GLN A HB2  1 c 
ATOM   8938  H  HB3  . GLN A 1 583 ? 5.598   24.03   18.075  1   50.736  ? 589  GLN A HB3  1 c 
ATOM   8939  H  HG2  . GLN A 1 583 ? 4.788   22.622  16.333  1   57.08   ? 589  GLN A HG2  1 c 
ATOM   8940  H  HG3  . GLN A 1 583 ? 3.641   23.187  17.262  1   57.211  ? 589  GLN A HG3  1 c 
ATOM   8941  H  HE21 . GLN A 1 583 ? 3.984   24.644  13.596  1   49.197  ? 589  GLN A HE21 1 c 
ATOM   8942  H  HE22 . GLN A 1 583 ? 5.024   25.071  14.642  1   49.167  ? 589  GLN A HE22 1 c 
ATOM   8943  N  N    . LYS A 1 584 ? 3.315   26.135  19.42   1   43.364  ? 590  LYS A N    1 ? 
ATOM   8944  C  CA   . LYS A 1 584 ? 2.946   26.163  20.826  1   52.093  ? 590  LYS A CA   1 ? 
ATOM   8945  C  C    . LYS A 1 584 ? 2.25    24.872  21.297  1   52.717  ? 590  LYS A C    1 ? 
ATOM   8946  O  O    . LYS A 1 584 ? 1.357   24.358  20.635  1   46.165  ? 590  LYS A O    1 ? 
ATOM   8947  C  CB   . LYS A 1 584 ? 1.884   27.229  21.105  1   62.266  ? 590  LYS A CB   1 ? 
ATOM   8948  C  CG   . LYS A 1 584 ? 2.409   28.501  21.71   1   80.14   ? 590  LYS A CG   1 ? 
ATOM   8949  C  CD   . LYS A 1 584 ? 1.408   29.273  22.554  1   80.443  ? 590  LYS A CD   1 ? 
ATOM   8950  C  CE   . LYS A 1 584 ? 2.084   30.471  23.166  1   89.285  ? 590  LYS A CE   1 ? 
ATOM   8951  N  NZ   . LYS A 1 584 ? 1.412   30.968  24.369  1   91.106  ? 590  LYS A NZ   1 ? 
ATOM   8952  H  H    . LYS A 1 584 ? 2.643   26.175  18.802  1   46.49   ? 590  LYS A H    1 c 
ATOM   8953  H  HA   . LYS A 1 584 ? 3.753   26.326  21.372  1   52.106  ? 590  LYS A HA   1 c 
ATOM   8954  H  HB2  . LYS A 1 584 ? 1.432   27.452  20.264  1   63.146  ? 590  LYS A HB2  1 c 
ATOM   8955  H  HB3  . LYS A 1 584 ? 1.21    26.856  21.713  1   63.385  ? 590  LYS A HB3  1 c 
ATOM   8956  H  HG2  . LYS A 1 584 ? 3.187   28.281  22.267  1   75.261  ? 590  LYS A HG2  1 c 
ATOM   8957  H  HG3  . LYS A 1 584 ? 2.722   29.082  20.982  1   75.528  ? 590  LYS A HG3  1 c 
ATOM   8958  H  HD2  . LYS A 1 584 ? 0.661   29.572  21.991  1   82.334  ? 590  LYS A HD2  1 c 
ATOM   8959  H  HD3  . LYS A 1 584 ? 1.058   28.694  23.265  1   82.375  ? 590  LYS A HD3  1 c 
ATOM   8960  H  HE2  . LYS A 1 584 ? 2.996   30.237  23.405  1   87.014  ? 590  LYS A HE2  1 c 
ATOM   8961  H  HE3  . LYS A 1 584 ? 2.122   31.188  22.508  1   87.493  ? 590  LYS A HE3  1 c 
ATOM   8962  H  HZ1  . LYS A 1 584 ? 1.175   30.276  24.903  1   90.105  ? 590  LYS A HZ1  1 c 
ATOM   8963  H  HZ2  . LYS A 1 584 ? 0.665   31.425  24.132  1   90.439  ? 590  LYS A HZ2  1 c 
ATOM   8964  H  HZ3  . LYS A 1 584 ? 1.966   31.522  24.824  1   90.439  ? 590  LYS A HZ3  1 c 
ATOM   8965  N  N    . VAL A 1 585 ? 2.587   24.39   22.504  1   45.023  ? 591  VAL A N    1 ? 
ATOM   8966  C  CA   . VAL A 1 585 ? 1.722   23.465  23.222  1   43.548  ? 591  VAL A CA   1 ? 
ATOM   8967  C  C    . VAL A 1 585 ? 1.56    23.987  24.649  1   45.223  ? 591  VAL A C    1 ? 
ATOM   8968  O  O    . VAL A 1 585 ? 2.396   24.745  25.151  1   43.201  ? 591  VAL A O    1 ? 
ATOM   8969  C  CB   . VAL A 1 585 ? 2.201   21.998  23.235  1   42.999  ? 591  VAL A CB   1 ? 
ATOM   8970  C  CG1  . VAL A 1 585 ? 2.138   21.328  21.873  1   42.396  ? 591  VAL A CG1  1 ? 
ATOM   8971  C  CG2  . VAL A 1 585 ? 3.61    21.854  23.806  1   51.373  ? 591  VAL A CG2  1 ? 
ATOM   8972  H  H    . VAL A 1 585 ? 3.378   24.642  22.886  1   46.474  ? 591  VAL A H    1 c 
ATOM   8973  H  HA   . VAL A 1 585 ? 0.842   23.487  22.797  1   44.107  ? 591  VAL A HA   1 c 
ATOM   8974  H  HB   . VAL A 1 585 ? 1.591   21.504  23.832  1   44.444  ? 591  VAL A HB   1 c 
ATOM   8975  H  HG11 . VAL A 1 585 ? 2.73    21.79   21.256  1   42.582  ? 591  VAL A HG11 1 c 
ATOM   8976  H  HG12 . VAL A 1 585 ? 1.227   21.363  21.535  1   42.582  ? 591  VAL A HG12 1 c 
ATOM   8977  H  HG13 . VAL A 1 585 ? 2.417   20.4    21.954  1   42.612  ? 591  VAL A HG13 1 c 
ATOM   8978  H  HG21 . VAL A 1 585 ? 3.9     20.93   23.726  1   48.658  ? 591  VAL A HG21 1 c 
ATOM   8979  H  HG22 . VAL A 1 585 ? 3.61    22.112  24.743  1   48.71   ? 591  VAL A HG22 1 c 
ATOM   8980  H  HG23 . VAL A 1 585 ? 4.221   22.427  23.313  1   48.707  ? 591  VAL A HG23 1 c 
ATOM   8981  N  N    . THR A 1 586 ? 0.485   23.556  25.317  1   45.894  ? 592  THR A N    1 ? 
ATOM   8982  C  CA   . THR A 1 586 ? 0.336   23.846  26.739  1   47.149  ? 592  THR A CA   1 ? 
ATOM   8983  C  C    . THR A 1 586 ? 0.147   22.536  27.506  1   40.7    ? 592  THR A C    1 ? 
ATOM   8984  O  O    . THR A 1 586 ? -0.705  21.728  27.143  1   41.597  ? 592  THR A O    1 ? 
ATOM   8985  C  CB   . THR A 1 586 ? -0.809  24.836  26.961  1   48.121  ? 592  THR A CB   1 ? 
ATOM   8986  O  OG1  . THR A 1 586 ? -0.283  26.051  26.444  1   45.835  ? 592  THR A OG1  1 ? 
ATOM   8987  C  CG2  . THR A 1 586 ? -1.143  25.02   28.43   1   47.85   ? 592  THR A CG2  1 ? 
ATOM   8988  H  H    . THR A 1 586 ? -0.163  23.075  24.887  1   45.977  ? 592  THR A H    1 c 
ATOM   8989  H  HA   . THR A 1 586 ? 1.163   24.268  27.051  1   45.745  ? 592  THR A HA   1 c 
ATOM   8990  H  HB   . THR A 1 586 ? -1.61   24.568  26.45   1   47.44   ? 592  THR A HB   1 c 
ATOM   8991  H  HG1  . THR A 1 586 ? 0.461   26.244  26.934  0   46.32   ? 592  THR A HG1  1 c 
ATOM   8992  H  HG21 . THR A 1 586 ? -1.76   25.765  28.53   1   47.92   ? 592  THR A HG21 1 c 
ATOM   8993  H  HG22 . THR A 1 586 ? -0.329  25.206  28.927  1   47.92   ? 592  THR A HG22 1 c 
ATOM   8994  H  HG23 . THR A 1 586 ? -1.556  24.211  28.775  1   47.888  ? 592  THR A HG23 1 c 
ATOM   8995  N  N    . LEU A 1 587 ? 0.994   22.325  28.524  1   44.338  ? 593  LEU A N    1 ? 
ATOM   8996  C  CA   . LEU A 1 587 ? 0.898   21.177  29.412  1   47.588  ? 593  LEU A CA   1 ? 
ATOM   8997  C  C    . LEU A 1 587 ? 0.216   21.594  30.722  1   47.39   ? 593  LEU A C    1 ? 
ATOM   8998  O  O    . LEU A 1 587 ? 0.726   22.427  31.463  1   46.592  ? 593  LEU A O    1 ? 
ATOM   8999  C  CB   . LEU A 1 587 ? 2.286   20.579  29.645  1   49.696  ? 593  LEU A CB   1 ? 
ATOM   9000  C  CG   . LEU A 1 587 ? 2.411   19.554  30.779  1   54.764  ? 593  LEU A CG   1 ? 
ATOM   9001  C  CD1  . LEU A 1 587 ? 1.394   18.455  30.702  1   60.264  ? 593  LEU A CD1  1 ? 
ATOM   9002  C  CD2  . LEU A 1 587 ? 3.795   18.937  30.748  1   63.556  ? 593  LEU A CD2  1 ? 
ATOM   9003  H  H    . LEU A 1 587 ? 1.664   22.93   28.671  1   44.223  ? 593  LEU A H    1 c 
ATOM   9004  H  HA   . LEU A 1 587 ? 0.332   20.495  28.971  1   47.231  ? 593  LEU A HA   1 c 
ATOM   9005  H  HB2  . LEU A 1 587 ? 2.577   20.149  28.808  1   50.352  ? 593  LEU A HB2  1 c 
ATOM   9006  H  HB3  . LEU A 1 587 ? 2.911   21.318  29.826  1   50.231  ? 593  LEU A HB3  1 c 
ATOM   9007  H  HG   . LEU A 1 587 ? 2.3     20.026  31.645  1   56.273  ? 593  LEU A HG   1 c 
ATOM   9008  H  HD11 . LEU A 1 587 ? 0.501   18.826  30.79   1   58.255  ? 593  LEU A HD11 1 c 
ATOM   9009  H  HD12 . LEU A 1 587 ? 1.551   17.821  31.42   1   58.377  ? 593  LEU A HD12 1 c 
ATOM   9010  H  HD13 . LEU A 1 587 ? 1.472   18      29.847  1   58.251  ? 593  LEU A HD13 1 c 
ATOM   9011  H  HD21 . LEU A 1 587 ? 4.464   19.633  30.861  1   60.809  ? 593  LEU A HD21 1 c 
ATOM   9012  H  HD22 . LEU A 1 587 ? 3.933   18.492  29.895  1   60.809  ? 593  LEU A HD22 1 c 
ATOM   9013  H  HD23 . LEU A 1 587 ? 3.879   18.289  31.467  1   60.797  ? 593  LEU A HD23 1 c 
ATOM   9014  N  N    . GLU A 1 588 ? -0.934  20.979  30.996  1   49.454  ? 594  GLU A N    1 ? 
ATOM   9015  C  CA   . GLU A 1 588 ? -1.711  21.239  32.197  1   55.647  ? 594  GLU A CA   1 ? 
ATOM   9016  C  C    . GLU A 1 588 ? -1.515  20.093  33.169  1   48.181  ? 594  GLU A C    1 ? 
ATOM   9017  O  O    . GLU A 1 588 ? -1.634  18.928  32.793  1   43.932  ? 594  GLU A O    1 ? 
ATOM   9018  C  CB   . GLU A 1 588 ? -3.222  21.25   31.954  1   55.957  ? 594  GLU A CB   1 ? 
ATOM   9019  C  CG   . GLU A 1 588 ? -3.718  22.439  31.146  1   53.468  ? 594  GLU A CG   1 ? 
ATOM   9020  C  CD   . GLU A 1 588 ? -5.105  22.198  30.586  1   58.136  ? 594  GLU A CD   1 ? 
ATOM   9021  O  OE1  . GLU A 1 588 ? -5.504  22.962  29.693  1   60.692  ? 594  GLU A OE1  1 ? 
ATOM   9022  O  OE2  . GLU A 1 588 ? -5.781  21.249  31.027  1   70.166  ? 594  GLU A OE2  1 ? 
ATOM   9023  H  H    . GLU A 1 588 ? -1.256  20.364  30.401  1   50.292  ? 594  GLU A H    1 c 
ATOM   9024  H  HA   . GLU A 1 588 ? -1.413  22.088  32.604  1   52.785  ? 594  GLU A HA   1 c 
ATOM   9025  H  HB2  . GLU A 1 588 ? -3.467  20.424  31.487  1   55.287  ? 594  GLU A HB2  1 c 
ATOM   9026  H  HB3  . GLU A 1 588 ? -3.682  21.251  32.82   1   55.258  ? 594  GLU A HB3  1 c 
ATOM   9027  H  HG2  . GLU A 1 588 ? -3.739  23.236  31.717  1   55.068  ? 594  GLU A HG2  1 c 
ATOM   9028  H  HG3  . GLU A 1 588 ? -3.1    22.609  30.403  1   55.069  ? 594  GLU A HG3  1 c 
ATOM   9029  N  N    . TYR A 1 589 ? -1.268  20.443  34.428  1   46.53   ? 595  TYR A N    1 ? 
ATOM   9030  C  CA   . TYR A 1 589 ? -0.967  19.447  35.437  1   44.494  ? 595  TYR A CA   1 ? 
ATOM   9031  C  C    . TYR A 1 589 ? -1.759  19.766  36.704  1   46.564  ? 595  TYR A C    1 ? 
ATOM   9032  O  O    . TYR A 1 589 ? -2.222  20.892  36.91   1   41.067  ? 595  TYR A O    1 ? 
ATOM   9033  C  CB   . TYR A 1 589 ? 0.546   19.438  35.648  1   41.358  ? 595  TYR A CB   1 ? 
ATOM   9034  C  CG   . TYR A 1 589 ? 1.091   20.767  36.15   1   49.685  ? 595  TYR A CG   1 ? 
ATOM   9035  C  CD1  . TYR A 1 589 ? 0.987   21.122  37.492  1   49.597  ? 595  TYR A CD1  1 ? 
ATOM   9036  C  CD2  . TYR A 1 589 ? 1.674   21.678  35.281  1   46.412  ? 595  TYR A CD2  1 ? 
ATOM   9037  C  CE1  . TYR A 1 589 ? 1.467   22.332  37.964  1   50.917  ? 595  TYR A CE1  1 ? 
ATOM   9038  C  CE2  . TYR A 1 589 ? 2.146   22.895  35.738  1   52.619  ? 595  TYR A CE2  1 ? 
ATOM   9039  C  CZ   . TYR A 1 589 ? 2.064   23.212  37.085  1   50.28   ? 595  TYR A CZ   1 ? 
ATOM   9040  O  OH   . TYR A 1 589 ? 2.534   24.411  37.508  1   50.947  ? 595  TYR A OH   1 ? 
ATOM   9041  H  H    . TYR A 1 589 ? -1.292  21.325  34.668  1   46.573  ? 595  TYR A H    1 c 
ATOM   9042  H  HA   . TYR A 1 589 ? -1.247  18.559  35.098  1   44.778  ? 595  TYR A HA   1 c 
ATOM   9043  H  HB2  . TYR A 1 589 ? 0.769   18.735  36.297  1   43.889  ? 595  TYR A HB2  1 c 
ATOM   9044  H  HB3  . TYR A 1 589 ? 0.981   19.216  34.795  1   43.877  ? 595  TYR A HB3  1 c 
ATOM   9045  H  HD1  . TYR A 1 589 ? 0.597   20.516  38.098  1   49.813  ? 595  TYR A HD1  1 c 
ATOM   9046  H  HD2  . TYR A 1 589 ? 1.745   21.467  34.364  1   48.549  ? 595  TYR A HD2  1 c 
ATOM   9047  H  HE1  . TYR A 1 589 ? 1.401   22.547  38.879  1   50.427  ? 595  TYR A HE1  1 c 
ATOM   9048  H  HE2  . TYR A 1 589 ? 2.553   23.498  35.138  1   50.529  ? 595  TYR A HE2  1 c 
ATOM   9049  H  HH   . TYR A 1 589 ? 3.388   24.33   37.77   0   49.89   ? 595  TYR A HH   1 c 
ATOM   9050  N  N    . PRO A 1 590 ? -1.986  18.758  37.566  1   51.078  ? 596  PRO A N    1 ? 
ATOM   9051  C  CA   . PRO A 1 590 ? -2.803  18.947  38.766  1   48.43   ? 596  PRO A CA   1 ? 
ATOM   9052  C  C    . PRO A 1 590 ? -2.163  19.896  39.78   1   45.953  ? 596  PRO A C    1 ? 
ATOM   9053  O  O    . PRO A 1 590 ? -0.93   19.981  39.878  1   45.234  ? 596  PRO A O    1 ? 
ATOM   9054  C  CB   . PRO A 1 590 ? -2.904  17.51   39.328  1   54.456  ? 596  PRO A CB   1 ? 
ATOM   9055  C  CG   . PRO A 1 590 ? -2.514  16.586  38.192  1   55.516  ? 596  PRO A CG   1 ? 
ATOM   9056  C  CD   . PRO A 1 590 ? -1.502  17.375  37.401  1   52.899  ? 596  PRO A CD   1 ? 
ATOM   9057  H  HA   . PRO A 1 590 ? -3.701  19.272  38.507  1   49.476  ? 596  PRO A HA   1 c 
ATOM   9058  H  HB2  . PRO A 1 590 ? -2.289  17.395  40.085  1   53.329  ? 596  PRO A HB2  1 c 
ATOM   9059  H  HB3  . PRO A 1 590 ? -3.821  17.319  39.634  1   53.331  ? 596  PRO A HB3  1 c 
ATOM   9060  H  HG2  . PRO A 1 590 ? -2.119  15.757  38.535  1   54.667  ? 596  PRO A HG2  1 c 
ATOM   9061  H  HG3  . PRO A 1 590 ? -3.291  16.363  37.639  1   54.645  ? 596  PRO A HG3  1 c 
ATOM   9062  H  HD2  . PRO A 1 590 ? -0.598  17.267  37.771  1   52.892  ? 596  PRO A HD2  1 c 
ATOM   9063  H  HD3  . PRO A 1 590 ? -1.503  17.101  36.459  1   52.839  ? 596  PRO A HD3  1 c 
ATOM   9064  N  N    . GLY A 1 591 ? -3.024  20.557  40.569  1   46.217  ? 597  GLY A N    1 ? 
ATOM   9065  C  CA   . GLY A 1 591 ? -2.626  21.473  41.636  1   49.45   ? 597  GLY A CA   1 ? 
ATOM   9066  C  C    . GLY A 1 591 ? -1.612  20.911  42.646  1   53.882  ? 597  GLY A C    1 ? 
ATOM   9067  O  O    . GLY A 1 591 ? -0.798  21.683  43.157  1   54.326  ? 597  GLY A O    1 ? 
ATOM   9068  H  H    . GLY A 1 591 ? -3.918  20.425  40.433  1   46.897  ? 597  GLY A H    1 c 
ATOM   9069  H  HA2  . GLY A 1 591 ? -2.243  22.281  41.221  1   49.596  ? 597  GLY A HA2  1 c 
ATOM   9070  H  HA3  . GLY A 1 591 ? -3.437  21.75   42.123  1   49.596  ? 597  GLY A HA3  1 c 
ATOM   9071  N  N    . GLU A 1 592 ? -1.616  19.587  42.91   1   48.737  ? 598  GLU A N    1 ? 
ATOM   9072  C  CA   . GLU A 1 592 ? -0.692  19.006  43.876  1   50.104  ? 598  GLU A CA   1 ? 
ATOM   9073  C  C    . GLU A 1 592 ? 0.788   19.192  43.51   1   51.986  ? 598  GLU A C    1 ? 
ATOM   9074  O  O    . GLU A 1 592 ? 1.645   19.02   44.384  1   46.356  ? 598  GLU A O    1 ? 
ATOM   9075  C  CB   . GLU A 1 592 ? -0.988  17.547  44.228  1   53.78   ? 598  GLU A CB   1 ? 
ATOM   9076  C  CG   . GLU A 1 592 ? -1.113  16.586  43.053  1   55.764  ? 598  GLU A CG   1 ? 
ATOM   9077  C  CD   . GLU A 1 592 ? -2.506  16.379  42.463  1   60.628  ? 598  GLU A CD   1 ? 
ATOM   9078  O  OE1  . GLU A 1 592 ? -2.828  15.205  42.136  1   54.737  ? 598  GLU A OE1  1 ? 
ATOM   9079  O  OE2  . GLU A 1 592 ? -3.24   17.385  42.264  1   59.766  ? 598  GLU A OE2  1 ? 
ATOM   9080  H  H    . GLU A 1 592 ? -2.216  19.043  42.486  1   50.265  ? 598  GLU A H    1 c 
ATOM   9081  H  HA   . GLU A 1 592 ? -0.83   19.5    44.724  1   50.884  ? 598  GLU A HA   1 c 
ATOM   9082  H  HB2  . GLU A 1 592 ? -0.28   17.219  44.818  1   53.301  ? 598  GLU A HB2  1 c 
ATOM   9083  H  HB3  . GLU A 1 592 ? -1.828  17.516  44.732  1   53.387  ? 598  GLU A HB3  1 c 
ATOM   9084  H  HG2  . GLU A 1 592 ? -0.526  16.9    42.333  1   56.353  ? 598  GLU A HG2  1 c 
ATOM   9085  H  HG3  . GLU A 1 592 ? -0.772  15.71   43.333  1   56.36   ? 598  GLU A HG3  1 c 
ATOM   9086  N  N    . PHE A 1 593 ? 1.123   19.563  42.261  1   47.258  ? 599  PHE A N    1 ? 
ATOM   9087  C  CA   . PHE A 1 593 ? 2.525   19.616  41.879  1   45.075  ? 599  PHE A CA   1 ? 
ATOM   9088  C  C    . PHE A 1 593 ? 3.051   21.051  41.9    1   47.19   ? 599  PHE A C    1 ? 
ATOM   9089  O  O    . PHE A 1 593 ? 2.317   21.998  41.591  1   44.637  ? 599  PHE A O    1 ? 
ATOM   9090  C  CB   . PHE A 1 593 ? 2.876   19.13   40.472  1   41.253  ? 599  PHE A CB   1 ? 
ATOM   9091  C  CG   . PHE A 1 593 ? 2.659   17.653  40.224  1   39.835  ? 599  PHE A CG   1 ? 
ATOM   9092  C  CD1  . PHE A 1 593 ? 1.45    17.177  39.76   1   43.814  ? 599  PHE A CD1  1 ? 
ATOM   9093  C  CD2  . PHE A 1 593 ? 3.694   16.754  40.413  1   40.652  ? 599  PHE A CD2  1 ? 
ATOM   9094  C  CE1  . PHE A 1 593 ? 1.263   15.819  39.534  1   46.407  ? 599  PHE A CE1  1 ? 
ATOM   9095  C  CE2  . PHE A 1 593 ? 3.496   15.394  40.196  1   46.64   ? 599  PHE A CE2  1 ? 
ATOM   9096  C  CZ   . PHE A 1 593 ? 2.293   14.934  39.731  1   44.207  ? 599  PHE A CZ   1 ? 
ATOM   9097  H  H    . PHE A 1 593 ? 0.481   19.768  41.643  1   47.879  ? 599  PHE A H    1 c 
ATOM   9098  H  HA   . PHE A 1 593 ? 3.048   19.079  42.53   1   45.167  ? 599  PHE A HA   1 c 
ATOM   9099  H  HB2  . PHE A 1 593 ? 2.337   19.639  39.826  1   41.79   ? 599  PHE A HB2  1 c 
ATOM   9100  H  HB3  . PHE A 1 593 ? 3.82    19.341  40.296  1   41.796  ? 599  PHE A HB3  1 c 
ATOM   9101  H  HD1  . PHE A 1 593 ? 0.737   17.779  39.617  1   43.494  ? 599  PHE A HD1  1 c 
ATOM   9102  H  HD2  . PHE A 1 593 ? 4.525   17.063  40.731  1   41.889  ? 599  PHE A HD2  1 c 
ATOM   9103  H  HE1  . PHE A 1 593 ? 0.428   15.507  39.221  1   45.213  ? 599  PHE A HE1  1 c 
ATOM   9104  H  HE2  . PHE A 1 593 ? 4.209   14.79   40.333  1   44.581  ? 599  PHE A HE2  1 c 
ATOM   9105  H  HZ   . PHE A 1 593 ? 2.165   14.014  39.579  1   45.239  ? 599  PHE A HZ   1 c 
ATOM   9106  N  N    . THR A 1 594 ? 4.356   21.15   42.198  1   44.033  ? 600  THR A N    1 ? 
ATOM   9107  C  CA   . THR A 1 594 ? 5.142   22.353  41.975  1   51.54   ? 600  THR A CA   1 ? 
ATOM   9108  C  C    . THR A 1 594 ? 6.037   22.114  40.759  1   50.131  ? 600  THR A C    1 ? 
ATOM   9109  O  O    . THR A 1 594 ? 6.688   21.072  40.69   1   52.148  ? 600  THR A O    1 ? 
ATOM   9110  C  CB   . THR A 1 594 ? 5.988   22.684  43.207  1   52.593  ? 600  THR A CB   1 ? 
ATOM   9111  O  OG1  . THR A 1 594 ? 5.176   22.521  44.371  1   62.562  ? 600  THR A OG1  1 ? 
ATOM   9112  C  CG2  . THR A 1 594 ? 6.485   24.12   43.185  1   56.345  ? 600  THR A CG2  1 ? 
ATOM   9113  H  H    . THR A 1 594 ? 4.777   20.425  42.563  1   46.372  ? 600  THR A H    1 c 
ATOM   9114  H  HA   . THR A 1 594 ? 4.536   23.103  41.792  1   49.818  ? 600  THR A HA   1 c 
ATOM   9115  H  HB   . THR A 1 594 ? 6.76    22.071  43.257  1   54.879  ? 600  THR A HB   1 c 
ATOM   9116  H  HG1  . THR A 1 594 ? 4.503   22.991  44.323  0   64.97   ? 600  THR A HG1  1 c 
ATOM   9117  H  HG21 . THR A 1 594 ? 7.003   24.296  43.988  1   55.203  ? 600  THR A HG21 1 c 
ATOM   9118  H  HG22 . THR A 1 594 ? 5.726   24.726  43.151  1   55.203  ? 600  THR A HG22 1 c 
ATOM   9119  H  HG23 . THR A 1 594 ? 7.045   24.258  42.403  1   55.185  ? 600  THR A HG23 1 c 
ATOM   9120  N  N    . ALA A 1 595 ? 6.117   23.123  39.881  1   42.872  ? 601  ALA A N    1 ? 
ATOM   9121  C  CA   . ALA A 1 595 ? 6.903   23.085  38.659  1   48.982  ? 601  ALA A CA   1 ? 
ATOM   9122  C  C    . ALA A 1 595 ? 8.214   23.87   38.783  1   54.762  ? 601  ALA A C    1 ? 
ATOM   9123  O  O    . ALA A 1 595 ? 8.21    25.031  39.185  1   54.241  ? 601  ALA A O    1 ? 
ATOM   9124  C  CB   . ALA A 1 595 ? 6.039   23.656  37.552  1   49.911  ? 601  ALA A CB   1 ? 
ATOM   9125  H  H    . ALA A 1 595 ? 5.652   23.889  40.063  1   45.986  ? 601  ALA A H    1 c 
ATOM   9126  H  HA   . ALA A 1 595 ? 7.118   22.136  38.45   1   48.882  ? 601  ALA A HA   1 c 
ATOM   9127  H  HB1  . ALA A 1 595 ? 5.236   23.116  37.453  1   49.628  ? 601  ALA A HB1  1 c 
ATOM   9128  H  HB2  . ALA A 1 595 ? 5.787   24.568  37.771  1   49.609  ? 601  ALA A HB2  1 c 
ATOM   9129  H  HB3  . ALA A 1 595 ? 6.533   23.651  36.715  1   49.628  ? 601  ALA A HB3  1 c 
ATOM   9130  N  N    . THR A 1 596 ? 9.336   23.242  38.401  1   50.784  ? 602  THR A N    1 ? 
ATOM   9131  C  CA   . THR A 1 596 ? 10.562  23.967  38.094  1   47.211  ? 602  THR A CA   1 ? 
ATOM   9132  C  C    . THR A 1 596 ? 11.016  23.62   36.672  1   47.437  ? 602  THR A C    1 ? 
ATOM   9133  O  O    . THR A 1 596 ? 10.578  22.628  36.096  1   38.2    ? 602  THR A O    1 ? 
ATOM   9134  C  CB   . THR A 1 596 ? 11.663  23.642  39.109  1   46.604  ? 602  THR A CB   1 ? 
ATOM   9135  O  OG1  . THR A 1 596 ? 11.773  22.236  38.994  1   50.207  ? 602  THR A OG1  1 ? 
ATOM   9136  C  CG2  . THR A 1 596 ? 11.322  24.07   40.526  1   48.214  ? 602  THR A CG2  1 ? 
ATOM   9137  H  H    . THR A 1 596 ? 9.338   22.331  38.332  1   50.833  ? 602  THR A H    1 c 
ATOM   9138  H  HA   . THR A 1 596 ? 10.375  24.93   38.136  1   47.888  ? 602  THR A HA   1 c 
ATOM   9139  H  HB   . THR A 1 596 ? 12.512  24.063  38.831  1   47.695  ? 602  THR A HB   1 c 
ATOM   9140  H  HG1  . THR A 1 596 ? 11.023  21.874  39.193  0   49.88   ? 602  THR A HG1  1 c 
ATOM   9141  H  HG21 . THR A 1 596 ? 12.027  23.783  41.131  1   47.73   ? 602  THR A HG21 1 c 
ATOM   9142  H  HG22 . THR A 1 596 ? 10.481  23.665  40.796  1   47.72   ? 602  THR A HG22 1 c 
ATOM   9143  H  HG23 . THR A 1 596 ? 11.24   25.038  40.562  1   47.729  ? 602  THR A HG23 1 c 
ATOM   9144  N  N    . VAL A 1 597 ? 11.905  24.456  36.121  1   47.443  ? 603  VAL A N    1 ? 
ATOM   9145  C  CA   . VAL A 1 597 ? 12.52   24.234  34.822  1   47.669  ? 603  VAL A CA   1 ? 
ATOM   9146  C  C    . VAL A 1 597 ? 14.026  24.329  34.993  1   46.441  ? 603  VAL A C    1 ? 
ATOM   9147  O  O    . VAL A 1 597 ? 14.529  25.401  35.3    1   44.249  ? 603  VAL A O    1 ? 
ATOM   9148  C  CB   . VAL A 1 597 ? 12.077  25.283  33.786  1   50.099  ? 603  VAL A CB   1 ? 
ATOM   9149  C  CG1  . VAL A 1 597 ? 12.361  24.806  32.373  1   54.423  ? 603  VAL A CG1  1 ? 
ATOM   9150  C  CG2  . VAL A 1 597 ? 10.621  25.676  33.941  1   55.737  ? 603  VAL A CG2  1 ? 
ATOM   9151  H  H    . VAL A 1 597 ? 12.139  25.208  36.585  1   47.487  ? 603  VAL A H    1 c 
ATOM   9152  H  HA   . VAL A 1 597 ? 12.284  23.345  34.5    1   47.82   ? 603  VAL A HA   1 c 
ATOM   9153  H  HB   . VAL A 1 597 ? 12.616  26.093  33.94   1   51.364  ? 603  VAL A HB   1 c 
ATOM   9154  H  HG11 . VAL A 1 597 ? 11.904  23.962  32.216  1   53.042  ? 603  VAL A HG11 1 c 
ATOM   9155  H  HG12 . VAL A 1 597 ? 13.318  24.683  32.257  1   52.975  ? 603  VAL A HG12 1 c 
ATOM   9156  H  HG13 . VAL A 1 597 ? 12.042  25.468  31.736  1   53.075  ? 603  VAL A HG13 1 c 
ATOM   9157  H  HG21 . VAL A 1 597 ? 10.352  26.229  33.188  1   54.01   ? 603  VAL A HG21 1 c 
ATOM   9158  H  HG22 . VAL A 1 597 ? 10.507  26.177  34.765  1   54.053  ? 603  VAL A HG22 1 c 
ATOM   9159  H  HG23 . VAL A 1 597 ? 10.069  24.876  33.969  1   54.015  ? 603  VAL A HG23 1 c 
ATOM   9160  N  N    . GLU A 1 598 ? 14.736  23.24   34.707  1   51.169  ? 604  GLU A N    1 ? 
ATOM   9161  C  CA   . GLU A 1 598 ? 16.186  23.185  34.848  1   52.491  ? 604  GLU A CA   1 ? 
ATOM   9162  C  C    . GLU A 1 598 ? 16.847  23.3    33.468  1   48.186  ? 604  GLU A C    1 ? 
ATOM   9163  O  O    . GLU A 1 598 ? 16.444  22.622  32.529  1   48.951  ? 604  GLU A O    1 ? 
ATOM   9164  C  CB   . GLU A 1 598 ? 16.488  21.845  35.526  1   58.399  ? 604  GLU A CB   1 ? 
ATOM   9165  C  CG   . GLU A 1 598 ? 15.553  21.51   36.694  1   62.282  ? 604  GLU A CG   1 ? 
ATOM   9166  C  CD   . GLU A 1 598 ? 15.854  20.215  37.443  1   56.862  ? 604  GLU A CD   1 ? 
ATOM   9167  O  OE1  . GLU A 1 598 ? 16.332  19.259  36.809  1   57.012  ? 604  GLU A OE1  1 ? 
ATOM   9168  O  OE2  . GLU A 1 598 ? 15.566  20.137  38.654  1   58.132  ? 604  GLU A OE2  1 ? 
ATOM   9169  H  H    . GLU A 1 598 ? 14.301  22.5    34.392  1   50.429  ? 604  GLU A H    1 c 
ATOM   9170  H  HA   . GLU A 1 598 ? 16.483  23.93   35.425  1   52.284  ? 604  GLU A HA   1 c 
ATOM   9171  H  HB2  . GLU A 1 598 ? 16.424  21.132  34.856  1   57.776  ? 604  GLU A HB2  1 c 
ATOM   9172  H  HB3  . GLU A 1 598 ? 17.411  21.861  35.855  1   57.825  ? 604  GLU A HB3  1 c 
ATOM   9173  H  HG2  . GLU A 1 598 ? 15.58   22.249  37.339  1   60.086  ? 604  GLU A HG2  1 c 
ATOM   9174  H  HG3  . GLU A 1 598 ? 14.634  21.455  36.358  1   59.974  ? 604  GLU A HG3  1 c 
ATOM   9175  N  N    . THR A 1 599 ? 17.862  24.156  33.328  1   44.407  ? 605  THR A N    1 ? 
ATOM   9176  C  CA   . THR A 1 599 ? 18.594  24.256  32.071  1   46.143  ? 605  THR A CA   1 ? 
ATOM   9177  C  C    . THR A 1 599 ? 19.588  23.089  31.966  1   43.879  ? 605  THR A C    1 ? 
ATOM   9178  O  O    . THR A 1 599 ? 20.242  22.723  32.925  1   49.372  ? 605  THR A O    1 ? 
ATOM   9179  C  CB   . THR A 1 599 ? 19.275  25.621  31.94   1   46.952  ? 605  THR A CB   1 ? 
ATOM   9180  O  OG1  . THR A 1 599 ? 18.336  26.681  32.128  1   40.577  ? 605  THR A OG1  1 ? 
ATOM   9181  C  CG2  . THR A 1 599 ? 19.854  25.821  30.55   1   49.653  ? 605  THR A CG2  1 ? 
ATOM   9182  H  H    . THR A 1 599 ? 18.107  24.689  34.029  1   45.774  ? 605  THR A H    1 c 
ATOM   9183  H  HA   . THR A 1 599 ? 17.945  24.174  31.338  1   45.512  ? 605  THR A HA   1 c 
ATOM   9184  H  HB   . THR A 1 599 ? 19.997  25.699  32.608  1   45.954  ? 605  THR A HB   1 c 
ATOM   9185  H  HG1  . THR A 1 599 ? 17.671  26.61   31.559  0   39.73   ? 605  THR A HG1  1 c 
ATOM   9186  H  HG21 . THR A 1 599 ? 20.215  26.72   30.476  1   48.833  ? 605  THR A HG21 1 c 
ATOM   9187  H  HG22 . THR A 1 599 ? 19.154  25.699  29.887  1   48.833  ? 605  THR A HG22 1 c 
ATOM   9188  H  HG23 . THR A 1 599 ? 20.563  25.175  30.396  1   48.813  ? 605  THR A HG23 1 c 
ATOM   9189  N  N    . ILE A 1 600 ? 19.635  22.437  30.805  1   41.53   ? 606  ILE A N    1 ? 
ATOM   9190  C  CA   . ILE A 1 600 ? 20.636  21.424  30.479  1   42.318  ? 606  ILE A CA   1 ? 
ATOM   9191  C  C    . ILE A 1 600 ? 21.512  21.941  29.331  1   43.436  ? 606  ILE A C    1 ? 
ATOM   9192  O  O    . ILE A 1 600 ? 21.049  21.978  28.185  1   42.886  ? 606  ILE A O    1 ? 
ATOM   9193  C  CB   . ILE A 1 600 ? 19.971  20.098  30.074  1   39.333  ? 606  ILE A CB   1 ? 
ATOM   9194  C  CG1  . ILE A 1 600 ? 18.954  19.632  31.135  1   37.731  ? 606  ILE A CG1  1 ? 
ATOM   9195  C  CG2  . ILE A 1 600 ? 21.02   19.018  29.753  1   39.503  ? 606  ILE A CG2  1 ? 
ATOM   9196  C  CD1  . ILE A 1 600 ? 17.999  18.572  30.627  1   38.972  ? 606  ILE A CD1  1 ? 
ATOM   9197  H  H    . ILE A 1 600 ? 19.005  22.634  30.173  1   42.31   ? 606  ILE A H    1 c 
ATOM   9198  H  HA   . ILE A 1 600 ? 21.197  21.266  31.262  1   41.864  ? 606  ILE A HA   1 c 
ATOM   9199  H  HB   . ILE A 1 600 ? 19.468  20.267  29.252  1   39.634  ? 606  ILE A HB   1 c 
ATOM   9200  H  HG12 . ILE A 1 600 ? 19.443  19.275  31.905  1   38.374  ? 606  ILE A HG12 1 c 
ATOM   9201  H  HG13 . ILE A 1 600 ? 18.435  20.404  31.44   1   38.389  ? 606  ILE A HG13 1 c 
ATOM   9202  H  HG21 . ILE A 1 600 ? 20.574  18.178  29.554  1   39.45   ? 606  ILE A HG21 1 c 
ATOM   9203  H  HG22 . ILE A 1 600 ? 21.607  18.896  30.518  1   39.456  ? 606  ILE A HG22 1 c 
ATOM   9204  H  HG23 . ILE A 1 600 ? 21.547  19.29   28.983  1   39.472  ? 606  ILE A HG23 1 c 
ATOM   9205  H  HD11 . ILE A 1 600 ? 17.515  18.912  29.851  1   38.598  ? 606  ILE A HD11 1 c 
ATOM   9206  H  HD12 . ILE A 1 600 ? 17.361  18.346  31.332  1   38.647  ? 606  ILE A HD12 1 c 
ATOM   9207  H  HD13 . ILE A 1 600 ? 18.496  17.771  30.374  1   38.619  ? 606  ILE A HD13 1 c 
ATOM   9208  N  N    . ASN A 1 601 ? 22.753  22.373  29.644  1   41.912  ? 607  ASN A N    1 ? 
ATOM   9209  C  CA   . ASN A 1 601 ? 23.655  22.87   28.62   1   45.015  ? 607  ASN A CA   1 ? 
ATOM   9210  C  C    . ASN A 1 601 ? 24.225  21.643  27.921  1   41.982  ? 607  ASN A C    1 ? 
ATOM   9211  O  O    . ASN A 1 601 ? 24.319  20.595  28.539  1   38.147  ? 607  ASN A O    1 ? 
ATOM   9212  C  CB   . ASN A 1 601 ? 24.741  23.799  29.156  1   49.349  ? 607  ASN A CB   1 ? 
ATOM   9213  C  CG   . ASN A 1 601 ? 24.182  24.997  29.889  1   51.055  ? 607  ASN A CG   1 ? 
ATOM   9214  O  OD1  . ASN A 1 601 ? 23.444  25.808  29.321  1   56.381  ? 607  ASN A OD1  1 ? 
ATOM   9215  N  ND2  . ASN A 1 601 ? 24.52   25.142  31.16   1   57.048  ? 607  ASN A ND2  1 ? 
ATOM   9216  H  H    . ASN A 1 601 ? 23.034  22.357  30.513  1   42.979  ? 607  ASN A H    1 c 
ATOM   9217  H  HA   . ASN A 1 601 ? 23.127  23.383  27.967  1   44.576  ? 607  ASN A HA   1 c 
ATOM   9218  H  HB2  . ASN A 1 601 ? 25.32   23.295  29.761  1   48.799  ? 607  ASN A HB2  1 c 
ATOM   9219  H  HB3  . ASN A 1 601 ? 25.288  24.112  28.408  1   48.726  ? 607  ASN A HB3  1 c 
ATOM   9220  H  HD21 . ASN A 1 601 ? 24.192  25.82   31.629  1   55.117  ? 607  ASN A HD21 1 c 
ATOM   9221  H  HD22 . ASN A 1 601 ? 25.073  24.566  31.547  1   55.029  ? 607  ASN A HD22 1 c 
ATOM   9222  N  N    . LEU A 1 602 ? 24.564  21.796  26.634  1   47.642  ? 608  LEU A N    1 ? 
ATOM   9223  C  CA   . LEU A 1 602 ? 24.982  20.696  25.771  1   45.532  ? 608  LEU A CA   1 ? 
ATOM   9224  C  C    . LEU A 1 602 ? 26.362  21.002  25.214  1   41.228  ? 608  LEU A C    1 ? 
ATOM   9225  O  O    . LEU A 1 602 ? 26.479  21.539  24.119  1   44.848  ? 608  LEU A O    1 ? 
ATOM   9226  C  CB   . LEU A 1 602 ? 23.946  20.554  24.643  1   47.327  ? 608  LEU A CB   1 ? 
ATOM   9227  C  CG   . LEU A 1 602 ? 22.52   20.169  25.072  1   38.614  ? 608  LEU A CG   1 ? 
ATOM   9228  C  CD1  . LEU A 1 602 ? 21.511  20.05   23.953  1   41.078  ? 608  LEU A CD1  1 ? 
ATOM   9229  C  CD2  . LEU A 1 602 ? 22.562  18.857  25.839  1   39.432  ? 608  LEU A CD2  1 ? 
ATOM   9230  H  H    . LEU A 1 602 ? 24.535  22.636  26.275  1   45.742  ? 608  LEU A H    1 c 
ATOM   9231  H  HA   . LEU A 1 602 ? 25.016  19.862  26.298  1   45.453  ? 608  LEU A HA   1 c 
ATOM   9232  H  HB2  . LEU A 1 602 ? 23.902  21.41   24.158  1   44.795  ? 608  LEU A HB2  1 c 
ATOM   9233  H  HB3  . LEU A 1 602 ? 24.274  19.873  24.011  1   44.796  ? 608  LEU A HB3  1 c 
ATOM   9234  H  HG   . LEU A 1 602 ? 22.192  20.868  25.694  1   40.746  ? 608  LEU A HG   1 c 
ATOM   9235  H  HD11 . LEU A 1 602 ? 21.366  20.923  23.552  1   40.345  ? 608  LEU A HD11 1 c 
ATOM   9236  H  HD12 . LEU A 1 602 ? 20.671  19.714  24.306  1   40.28   ? 608  LEU A HD12 1 c 
ATOM   9237  H  HD13 . LEU A 1 602 ? 21.846  19.436  23.278  1   40.323  ? 608  LEU A HD13 1 c 
ATOM   9238  H  HD21 . LEU A 1 602 ? 22.998  18.993  26.696  1   39.269  ? 608  LEU A HD21 1 c 
ATOM   9239  H  HD22 . LEU A 1 602 ? 23.057  18.196  25.326  1   39.212  ? 608  LEU A HD22 1 c 
ATOM   9240  H  HD23 . LEU A 1 602 ? 21.656  18.537  25.987  1   39.226  ? 608  LEU A HD23 1 c 
ATOM   9241  N  N    . PRO A 1 603 ? 27.445  20.752  25.98   1   51.462  ? 609  PRO A N    1 ? 
ATOM   9242  C  CA   . PRO A 1 603 ? 28.811  20.881  25.455  1   52.882  ? 609  PRO A CA   1 ? 
ATOM   9243  C  C    . PRO A 1 603 ? 29.121  19.899  24.325  1   54.58   ? 609  PRO A C    1 ? 
ATOM   9244  O  O    . PRO A 1 603 ? 29.811  20.25   23.376  1   60.123  ? 609  PRO A O    1 ? 
ATOM   9245  C  CB   . PRO A 1 603 ? 29.694  20.624  26.691  1   59.448  ? 609  PRO A CB   1 ? 
ATOM   9246  C  CG   . PRO A 1 603 ? 28.807  19.797  27.619  1   59.681  ? 609  PRO A CG   1 ? 
ATOM   9247  C  CD   . PRO A 1 603 ? 27.408  20.353  27.402  1   56.567  ? 609  PRO A CD   1 ? 
ATOM   9248  H  HA   . PRO A 1 603 ? 28.948  21.809  25.139  1   53.988  ? 609  PRO A HA   1 c 
ATOM   9249  H  HB2  . PRO A 1 603 ? 30.509  20.125  26.446  1   57.954  ? 609  PRO A HB2  1 c 
ATOM   9250  H  HB3  . PRO A 1 603 ? 29.956  21.473  27.119  1   57.97   ? 609  PRO A HB3  1 c 
ATOM   9251  H  HG2  . PRO A 1 603 ? 28.844  18.846  27.384  1   58.84   ? 609  PRO A HG2  1 c 
ATOM   9252  H  HG3  . PRO A 1 603 ? 29.082  19.903  28.554  1   58.898  ? 609  PRO A HG3  1 c 
ATOM   9253  H  HD2  . PRO A 1 603 ? 26.727  19.669  27.568  1   55.867  ? 609  PRO A HD2  1 c 
ATOM   9254  H  HD3  . PRO A 1 603 ? 27.24   21.128  27.984  1   55.98   ? 609  PRO A HD3  1 c 
ATOM   9255  N  N    . ASP A 1 604 ? 28.599  18.67   24.431  1   47.318  ? 610  ASP A N    1 ? 
ATOM   9256  C  CA   . ASP A 1 604 ? 28.741  17.651  23.4    1   48.177  ? 610  ASP A CA   1 ? 
ATOM   9257  C  C    . ASP A 1 604 ? 28.052  18.126  22.106  1   50.294  ? 610  ASP A C    1 ? 
ATOM   9258  O  O    . ASP A 1 604 ? 26.826  18.154  22.029  1   47.185  ? 610  ASP A O    1 ? 
ATOM   9259  C  CB   . ASP A 1 604 ? 28.243  16.32   23.953  1   43.99   ? 610  ASP A CB   1 ? 
ATOM   9260  C  CG   . ASP A 1 604 ? 28.439  15.12   23.051  1   48.958  ? 610  ASP A CG   1 ? 
ATOM   9261  O  OD1  . ASP A 1 604 ? 28.834  15.333  21.884  1   49.043  ? 610  ASP A OD1  1 ? 
ATOM   9262  O  OD2  . ASP A 1 604 ? 28.189  13.995  23.524  1   47.147  ? 610  ASP A OD2  1 ? 
ATOM   9263  H  H    . ASP A 1 604 ? 28.131  18.456  25.187  1   49.275  ? 610  ASP A H    1 c 
ATOM   9264  H  HA   . ASP A 1 604 ? 29.701  17.541  23.215  1   47.624  ? 610  ASP A HA   1 c 
ATOM   9265  H  HB2  . ASP A 1 604 ? 28.705  16.142  24.798  1   46.033  ? 610  ASP A HB2  1 c 
ATOM   9266  H  HB3  . ASP A 1 604 ? 27.286  16.402  24.146  1   46.033  ? 610  ASP A HB3  1 c 
ATOM   9267  N  N    . THR A 1 605 ? 28.843  18.492  21.079  1   47.645  ? 611  THR A N    1 ? 
ATOM   9268  C  CA   . THR A 1 605 ? 28.328  18.992  19.805  1   45.412  ? 611  THR A CA   1 ? 
ATOM   9269  C  C    . THR A 1 605 ? 27.492  17.911  19.081  1   44.63   ? 611  THR A C    1 ? 
ATOM   9270  O  O    . THR A 1 605 ? 26.747  18.207  18.154  1   45.166  ? 611  THR A O    1 ? 
ATOM   9271  C  CB   . THR A 1 605 ? 29.474  19.508  18.91   1   47.445  ? 611  THR A CB   1 ? 
ATOM   9272  O  OG1  . THR A 1 605 ? 30.329  18.396  18.659  1   45.776  ? 611  THR A OG1  1 ? 
ATOM   9273  C  CG2  . THR A 1 605 ? 30.339  20.606  19.519  1   47.871  ? 611  THR A CG2  1 ? 
ATOM   9274  H  H    . THR A 1 605 ? 29.749  18.417  21.179  1   47.745  ? 611  THR A H    1 c 
ATOM   9275  H  HA   . THR A 1 605 ? 27.74   19.746  20.003  1   46.038  ? 611  THR A HA   1 c 
ATOM   9276  H  HB   . THR A 1 605 ? 29.102  19.831  18.055  1   46.821  ? 611  THR A HB   1 c 
ATOM   9277  H  HG1  . THR A 1 605 ? 30.61   18.085  19.418  0   46.74   ? 611  THR A HG1  1 c 
ATOM   9278  H  HG21 . THR A 1 605 ? 31.009  20.887  18.873  1   47.745  ? 611  THR A HG21 1 c 
ATOM   9279  H  HG22 . THR A 1 605 ? 30.781  20.269  20.316  1   47.744  ? 611  THR A HG22 1 c 
ATOM   9280  H  HG23 . THR A 1 605 ? 29.781  21.365  19.756  1   47.745  ? 611  THR A HG23 1 c 
ATOM   9281  N  N    . ARG A 1 606 ? 27.628  16.637  19.431  1   39.793  ? 612  ARG A N    1 ? 
ATOM   9282  C  CA   . ARG A 1 606 ? 26.808  15.632  18.78   1   42.639  ? 612  ARG A CA   1 ? 
ATOM   9283  C  C    . ARG A 1 606 ? 25.337  15.826  19.177  1   44.085  ? 612  ARG A C    1 ? 
ATOM   9284  O  O    . ARG A 1 606 ? 24.447  15.329  18.49   1   46.126  ? 612  ARG A O    1 ? 
ATOM   9285  C  CB   . ARG A 1 606 ? 27.308  14.215  19.094  1   44.486  ? 612  ARG A CB   1 ? 
ATOM   9286  C  CG   . ARG A 1 606 ? 26.627  13.113  18.295  1   46.004  ? 612  ARG A CG   1 ? 
ATOM   9287  C  CD   . ARG A 1 606 ? 27.223  11.757  18.554  1   55.104  ? 612  ARG A CD   1 ? 
ATOM   9288  N  NE   . ARG A 1 606 ? 26.926  10.783  17.495  1   61.324  ? 612  ARG A NE   1 ? 
ATOM   9289  C  CZ   . ARG A 1 606 ? 27.224  9.485   17.543  1   68.711  ? 612  ARG A CZ   1 ? 
ATOM   9290  N  NH1  . ARG A 1 606 ? 27.799  8.954   18.615  1   61.196  ? 612  ARG A NH1  1 ? 
ATOM   9291  N  NH2  . ARG A 1 606 ? 26.931  8.714   16.512  1   69.679  ? 612  ARG A NH2  1 ? 
ATOM   9292  H  H    . ARG A 1 606 ? 28.242  16.382  20.059  1   41.645  ? 612  ARG A H    1 c 
ATOM   9293  H  HA   . ARG A 1 606 ? 26.882  15.763  17.8    1   42.679  ? 612  ARG A HA   1 c 
ATOM   9294  H  HB2  . ARG A 1 606 ? 28.273  14.178  18.92   1   44.46   ? 612  ARG A HB2  1 c 
ATOM   9295  H  HB3  . ARG A 1 606 ? 27.171  14.039  20.049  1   44.413  ? 612  ARG A HB3  1 c 
ATOM   9296  H  HG2  . ARG A 1 606 ? 25.673  13.087  18.525  1   47.598  ? 612  ARG A HG2  1 c 
ATOM   9297  H  HG3  . ARG A 1 606 ? 26.702  13.317  17.337  1   47.682  ? 612  ARG A HG3  1 c 
ATOM   9298  H  HD2  . ARG A 1 606 ? 28.194  11.846  18.644  1   54.088  ? 612  ARG A HD2  1 c 
ATOM   9299  H  HD3  . ARG A 1 606 ? 26.875  11.42   19.403  1   54.176  ? 612  ARG A HD3  1 c 
ATOM   9300  H  HE   . ARG A 1 606 ? 26.523  11.075  16.78   1   61.339  ? 612  ARG A HE   1 c 
ATOM   9301  H  HH11 . ARG A 1 606 ? 28.266  9.464   19.171  1   63.298  ? 612  ARG A HH11 1 c 
ATOM   9302  H  HH12 . ARG A 1 606 ? 27.714  8.083   18.77   1   63.477  ? 612  ARG A HH12 1 c 
ATOM   9303  H  HH21 . ARG A 1 606 ? 26.522  9.054   15.806  1   69.212  ? 612  ARG A HH21 1 c 
ATOM   9304  H  HH22 . ARG A 1 606 ? 27.146  7.856   16.529  1   69.229  ? 612  ARG A HH22 1 c 
ATOM   9305  N  N    . LEU A 1 607 ? 25.109  16.488  20.319  1   39.685  ? 613  LEU A N    1 ? 
ATOM   9306  C  CA   . LEU A 1 607 ? 23.794  16.827  20.832  1   38.626  ? 613  LEU A CA   1 ? 
ATOM   9307  C  C    . LEU A 1 607 ? 23.447  18.26   20.426  1   39.235  ? 613  LEU A C    1 ? 
ATOM   9308  O  O    . LEU A 1 607 ? 22.316  18.519  20.005  1   39.027  ? 613  LEU A O    1 ? 
ATOM   9309  C  CB   . LEU A 1 607 ? 23.718  16.666  22.362  1   35.48   ? 613  LEU A CB   1 ? 
ATOM   9310  C  CG   . LEU A 1 607 ? 23.72   15.233  22.919  1   40.982  ? 613  LEU A CG   1 ? 
ATOM   9311  C  CD1  . LEU A 1 607 ? 23.905  15.25   24.425  1   44.335  ? 613  LEU A CD1  1 ? 
ATOM   9312  C  CD2  . LEU A 1 607 ? 22.45   14.423  22.583  1   42.372  ? 613  LEU A CD2  1 ? 
ATOM   9313  H  H    . LEU A 1 607 ? 25.83   16.722  20.828  1   40.484  ? 613  LEU A H    1 c 
ATOM   9314  H  HA   . LEU A 1 607 ? 23.132  16.219  20.415  1   38.456  ? 613  LEU A HA   1 c 
ATOM   9315  H  HB2  . LEU A 1 607 ? 24.479  17.151  22.757  1   37.476  ? 613  LEU A HB2  1 c 
ATOM   9316  H  HB3  . LEU A 1 607 ? 22.899  17.116  22.675  1   37.404  ? 613  LEU A HB3  1 c 
ATOM   9317  H  HG   . LEU A 1 607 ? 24.495  14.754  22.526  1   40.748  ? 613  LEU A HG   1 c 
ATOM   9318  H  HD11 . LEU A 1 607 ? 24.756  15.668  24.644  1   43.313  ? 613  LEU A HD11 1 c 
ATOM   9319  H  HD12 . LEU A 1 607 ? 23.896  14.34   24.765  1   43.306  ? 613  LEU A HD12 1 c 
ATOM   9320  H  HD13 . LEU A 1 607 ? 23.183  15.755  24.836  1   43.313  ? 613  LEU A HD13 1 c 
ATOM   9321  H  HD21 . LEU A 1 607 ? 22.368  14.331  21.619  1   41.939  ? 613  LEU A HD21 1 c 
ATOM   9322  H  HD22 . LEU A 1 607 ? 21.668  14.885  22.931  1   41.959  ? 613  LEU A HD22 1 c 
ATOM   9323  H  HD23 . LEU A 1 607 ? 22.51   13.541  22.988  1   41.965  ? 613  LEU A HD23 1 c 
ATOM   9324  N  N    . SER A 1 608 ? 24.399  19.199  20.593  1   39.726  ? 614  SER A N    1 ? 
ATOM   9325  C  CA   . SER A 1 608 ? 24.153  20.61   20.309  1   39.416  ? 614  SER A CA   1 ? 
ATOM   9326  C  C    . SER A 1 608 ? 23.921  20.865  18.808  1   37.753  ? 614  SER A C    1 ? 
ATOM   9327  O  O    . SER A 1 608 ? 23.283  21.847  18.444  1   37.081  ? 614  SER A O    1 ? 
ATOM   9328  C  CB   . SER A 1 608 ? 25.281  21.482  20.86   1   40.212  ? 614  SER A CB   1 ? 
ATOM   9329  O  OG   . SER A 1 608 ? 26.403  21.433  19.995  1   42.935  ? 614  SER A OG   1 ? 
ATOM   9330  H  H    . SER A 1 608 ? 25.224  18.951  20.898  1   39.554  ? 614  SER A H    1 c 
ATOM   9331  H  HA   . SER A 1 608 ? 23.322  20.861  20.782  1   39.348  ? 614  SER A HA   1 c 
ATOM   9332  H  HB2  . SER A 1 608 ? 24.97   22.404  20.941  1   40.668  ? 614  SER A HB2  1 c 
ATOM   9333  H  HB3  . SER A 1 608 ? 25.535  21.162  21.745  1   40.679  ? 614  SER A HB3  1 c 
ATOM   9334  H  HG   . SER A 1 608 ? 27.035  21.896  20.342  0   41.4    ? 614  SER A HG   1 c 
ATOM   9335  N  N    . ASN A 1 609 ? 24.454  20.014  17.93   1   34.501  ? 615  ASN A N    1 ? 
ATOM   9336  C  CA   . ASN A 1 609 ? 24.202  20.115  16.495  1   41.177  ? 615  ASN A CA   1 ? 
ATOM   9337  C  C    . ASN A 1 609 ? 22.752  19.795  16.166  1   41.947  ? 615  ASN A C    1 ? 
ATOM   9338  O  O    . ASN A 1 609 ? 22.248  20.202  15.114  1   36.551  ? 615  ASN A O    1 ? 
ATOM   9339  C  CB   . ASN A 1 609 ? 25.025  19.133  15.66   1   39.613  ? 615  ASN A CB   1 ? 
ATOM   9340  C  CG   . ASN A 1 609 ? 26.476  19.567  15.561  1   42.3    ? 615  ASN A CG   1 ? 
ATOM   9341  O  OD1  . ASN A 1 609 ? 26.785  20.736  15.795  1   39.489  ? 615  ASN A OD1  1 ? 
ATOM   9342  N  ND2  . ASN A 1 609 ? 27.374  18.665  15.194  1   41.613  ? 615  ASN A ND2  1 ? 
ATOM   9343  H  H    . ASN A 1 609 ? 25.004  19.349  18.23   1   36.751  ? 615  ASN A H    1 c 
ATOM   9344  H  HA   . ASN A 1 609 ? 24.409  21.028  16.195  1   39.64   ? 615  ASN A HA   1 c 
ATOM   9345  H  HB2  . ASN A 1 609 ? 24.981  18.245  16.068  1   40.564  ? 615  ASN A HB2  1 c 
ATOM   9346  H  HB3  . ASN A 1 609 ? 24.646  19.073  14.76   1   40.553  ? 615  ASN A HB3  1 c 
ATOM   9347  H  HD21 . ASN A 1 609 ? 28.23   18.89   15.135  1   41.801  ? 615  ASN A HD21 1 c 
ATOM   9348  H  HD22 . ASN A 1 609 ? 27.119  17.836  15.007  1   41.803  ? 615  ASN A HD22 1 c 
ATOM   9349  N  N    . VAL A 1 610 ? 22.126  19.018  17.059  1   43.932  ? 616  VAL A N    1 ? 
ATOM   9350  C  CA   . VAL A 1 610 ? 20.755  18.584  16.897  1   38.308  ? 616  VAL A CA   1 ? 
ATOM   9351  C  C    . VAL A 1 610 ? 19.856  19.597  17.592  1   38.162  ? 616  VAL A C    1 ? 
ATOM   9352  O  O    . VAL A 1 610 ? 18.952  20.116  16.941  1   36.393  ? 616  VAL A O    1 ? 
ATOM   9353  C  CB   . VAL A 1 610 ? 20.556  17.156  17.45   1   43.015  ? 616  VAL A CB   1 ? 
ATOM   9354  C  CG1  . VAL A 1 610 ? 19.083  16.744  17.486  1   40.848  ? 616  VAL A CG1  1 ? 
ATOM   9355  C  CG2  . VAL A 1 610 ? 21.366  16.125  16.665  1   43.458  ? 616  VAL A CG2  1 ? 
ATOM   9356  H  H    . VAL A 1 610 ? 22.585  18.728  17.794  1   42.003  ? 616  VAL A H    1 c 
ATOM   9357  H  HA   . VAL A 1 610 ? 20.54   18.579  15.944  1   40.119  ? 616  VAL A HA   1 c 
ATOM   9358  H  HB   . VAL A 1 610 ? 20.889  17.154  18.377  1   41.765  ? 616  VAL A HB   1 c 
ATOM   9359  H  HG11 . VAL A 1 610 ? 18.688  16.872  16.607  1   41.455  ? 616  VAL A HG11 1 c 
ATOM   9360  H  HG12 . VAL A 1 610 ? 18.607  17.285  18.137  1   41.441  ? 616  VAL A HG12 1 c 
ATOM   9361  H  HG13 . VAL A 1 610 ? 19.016  15.807  17.736  1   41.415  ? 616  VAL A HG13 1 c 
ATOM   9362  H  HG21 . VAL A 1 610 ? 21.202  15.238  17.027  1   43.315  ? 616  VAL A HG21 1 c 
ATOM   9363  H  HG22 . VAL A 1 610 ? 22.313  16.333  16.735  1   43.327  ? 616  VAL A HG22 1 c 
ATOM   9364  H  HG23 . VAL A 1 610 ? 21.099  16.146  15.73   1   43.325  ? 616  VAL A HG23 1 c 
ATOM   9365  N  N    . TRP A 1 611 ? 20.107  19.875  18.894  1   36.692  ? 617  TRP A N    1 ? 
ATOM   9366  C  CA   . TRP A 1 611 ? 19.156  20.646  19.701  1   36.611  ? 617  TRP A CA   1 ? 
ATOM   9367  C  C    . TRP A 1 611 ? 19.558  22.1    19.966  1   35.177  ? 617  TRP A C    1 ? 
ATOM   9368  O  O    . TRP A 1 611 ? 18.851  22.798  20.697  1   38.516  ? 617  TRP A O    1 ? 
ATOM   9369  C  CB   . TRP A 1 611 ? 18.922  19.986  21.069  1   34.659  ? 617  TRP A CB   1 ? 
ATOM   9370  C  CG   . TRP A 1 611 ? 18.429  18.567  21.031  1   35.31   ? 617  TRP A CG   1 ? 
ATOM   9371  C  CD1  . TRP A 1 611 ? 19.103  17.449  21.416  1   34.571  ? 617  TRP A CD1  1 ? 
ATOM   9372  C  CD2  . TRP A 1 611 ? 17.141  18.128  20.575  1   32.829  ? 617  TRP A CD2  1 ? 
ATOM   9373  N  NE1  . TRP A 1 611 ? 18.328  16.344  21.237  1   35.622  ? 617  TRP A NE1  1 ? 
ATOM   9374  C  CE2  . TRP A 1 611 ? 17.122  16.727  20.717  1   32.648  ? 617  TRP A CE2  1 ? 
ATOM   9375  C  CE3  . TRP A 1 611 ? 16.016  18.786  20.074  1   34.352  ? 617  TRP A CE3  1 ? 
ATOM   9376  C  CZ2  . TRP A 1 611 ? 16.009  15.963  20.383  1   32.686  ? 617  TRP A CZ2  1 ? 
ATOM   9377  C  CZ3  . TRP A 1 611 ? 14.921  18.027  19.733  1   35.004  ? 617  TRP A CZ3  1 ? 
ATOM   9378  C  CH2  . TRP A 1 611 ? 14.927  16.642  19.876  1   36.595  ? 617  TRP A CH2  1 ? 
ATOM   9379  H  H    . TRP A 1 611 ? 20.879  19.578  19.282  1   37.069  ? 617  TRP A H    1 c 
ATOM   9380  H  HA   . TRP A 1 611 ? 18.285  20.654  19.221  1   36.011  ? 617  TRP A HA   1 c 
ATOM   9381  H  HB2  . TRP A 1 611 ? 19.765  20.011  21.57   1   35.245  ? 617  TRP A HB2  1 c 
ATOM   9382  H  HB3  . TRP A 1 611 ? 18.274  20.527  21.567  1   35.257  ? 617  TRP A HB3  1 c 
ATOM   9383  H  HD1  . TRP A 1 611 ? 19.983  17.432  21.757  1   34.947  ? 617  TRP A HD1  1 c 
ATOM   9384  H  HE1  . TRP A 1 611 ? 18.567  15.524  21.417  1   34.642  ? 617  TRP A HE1  1 c 
ATOM   9385  H  HE3  . TRP A 1 611 ? 16.011  19.722  19.967  1   34.168  ? 617  TRP A HE3  1 c 
ATOM   9386  H  HZ2  . TRP A 1 611 ? 16.007  15.025  20.477  1   33.584  ? 617  TRP A HZ2  1 c 
ATOM   9387  H  HZ3  . TRP A 1 611 ? 14.154  18.452  19.386  1   35.169  ? 617  TRP A HZ3  1 c 
ATOM   9388  H  HH2  . TRP A 1 611 ? 14.157  16.155  19.637  1   35.23   ? 617  TRP A HH2  1 c 
ATOM   9389  N  N    . GLY A 1 612 ? 20.688  22.574  19.444  1   41.34   ? 618  GLY A N    1 ? 
ATOM   9390  C  CA   . GLY A 1 612 ? 21.198  23.863  19.899  1   39.876  ? 618  GLY A CA   1 ? 
ATOM   9391  C  C    . GLY A 1 612 ? 21.903  23.76   21.263  1   43.963  ? 618  GLY A C    1 ? 
ATOM   9392  O  O    . GLY A 1 612 ? 22.239  22.671  21.74   1   45.882  ? 618  GLY A O    1 ? 
ATOM   9393  H  H    . GLY A 1 612 ? 21.144  22.107  18.805  1   39.434  ? 618  GLY A H    1 c 
ATOM   9394  H  HA2  . GLY A 1 612 ? 21.833  24.205  19.232  1   41.09   ? 618  GLY A HA2  1 c 
ATOM   9395  H  HA3  . GLY A 1 612 ? 20.452  24.504  19.96   1   41.045  ? 618  GLY A HA3  1 c 
ATOM   9396  N  N    . THR A 1 613 ? 22.139  24.902  21.92   1   44.265  ? 619  THR A N    1 ? 
ATOM   9397  C  CA   . THR A 1 613 ? 23.145  24.942  22.986  1   49.314  ? 619  THR A CA   1 ? 
ATOM   9398  C  C    . THR A 1 613 ? 22.571  24.485  24.334  1   47.028  ? 619  THR A C    1 ? 
ATOM   9399  O  O    . THR A 1 613 ? 23.327  24.23   25.27   1   49.223  ? 619  THR A O    1 ? 
ATOM   9400  C  CB   . THR A 1 613 ? 23.773  26.341  23.055  1   50.399  ? 619  THR A CB   1 ? 
ATOM   9401  O  OG1  . THR A 1 613 ? 22.78   27.35   23.112  1   44.994  ? 619  THR A OG1  1 ? 
ATOM   9402  C  CG2  . THR A 1 613 ? 24.524  26.694  21.784  1   54.63   ? 619  THR A CG2  1 ? 
ATOM   9403  H  H    . THR A 1 613 ? 21.675  25.661  21.709  1   45.262  ? 619  THR A H    1 c 
ATOM   9404  H  HA   . THR A 1 613 ? 23.859  24.314  22.739  1   48.026  ? 619  THR A HA   1 c 
ATOM   9405  H  HB   . THR A 1 613 ? 24.37   26.414  23.838  1   49.822  ? 619  THR A HB   1 c 
ATOM   9406  H  HG1  . THR A 1 613 ? 22.298  27.321  22.342  0   44.59   ? 619  THR A HG1  1 c 
ATOM   9407  H  HG21 . THR A 1 613 ? 24.852  27.606  21.846  1   53.27   ? 619  THR A HG21 1 c 
ATOM   9408  H  HG22 . THR A 1 613 ? 23.927  26.617  21.021  1   53.274  ? 619  THR A HG22 1 c 
ATOM   9409  H  HG23 . THR A 1 613 ? 25.275  26.087  21.67   1   53.316  ? 619  THR A HG23 1 c 
ATOM   9410  N  N    . GLU A 1 614 ? 21.245  24.307  24.421  1   50.215  ? 620  GLU A N    1 ? 
ATOM   9411  C  CA   . GLU A 1 614 ? 20.589  23.994  25.682  1   51.859  ? 620  GLU A CA   1 ? 
ATOM   9412  C  C    . GLU A 1 614 ? 19.158  23.484  25.48   1   44.632  ? 620  GLU A C    1 ? 
ATOM   9413  O  O    . GLU A 1 614 ? 18.391  23.995  24.65   1   42.914  ? 620  GLU A O    1 ? 
ATOM   9414  C  CB   . GLU A 1 614 ? 20.551  25.261  26.535  1   49.377  ? 620  GLU A CB   1 ? 
ATOM   9415  C  CG   . GLU A 1 614 ? 20.555  26.481  25.619  1   63.313  ? 620  GLU A CG   1 ? 
ATOM   9416  C  CD   . GLU A 1 614 ? 19.911  27.689  26.22   1   81.271  ? 620  GLU A CD   1 ? 
ATOM   9417  O  OE1  . GLU A 1 614 ? 19.679  28.607  25.4    1   91.295  ? 620  GLU A OE1  1 ? 
ATOM   9418  O  OE2  . GLU A 1 614 ? 19.661  27.699  27.454  1   82.057  ? 620  GLU A OE2  1 ? 
ATOM   9419  H  H    . GLU A 1 614 ? 20.731  24.381  23.669  1   49.835  ? 620  GLU A H    1 c 
ATOM   9420  H  HA   . GLU A 1 614 ? 21.118  23.299  26.145  1   49.518  ? 620  GLU A HA   1 c 
ATOM   9421  H  HB2  . GLU A 1 614 ? 19.749  25.249  27.098  1   53.021  ? 620  GLU A HB2  1 c 
ATOM   9422  H  HB3  . GLU A 1 614 ? 21.336  25.278  27.122  1   52.86   ? 620  GLU A HB3  1 c 
ATOM   9423  H  HG2  . GLU A 1 614 ? 21.481  26.708  25.388  1   63.153  ? 620  GLU A HG2  1 c 
ATOM   9424  H  HG3  . GLU A 1 614 ? 20.082  26.264  24.788  1   63.28   ? 620  GLU A HG3  1 c 
ATOM   9425  N  N    . ILE A 1 615 ? 18.788  22.531  26.349  1   40.469  ? 621  ILE A N    1 ? 
ATOM   9426  C  CA   . ILE A 1 615 ? 17.423  22.056  26.443  1   41.42   ? 621  ILE A CA   1 ? 
ATOM   9427  C  C    . ILE A 1 615 ? 16.981  22.198  27.902  1   45.15   ? 621  ILE A C    1 ? 
ATOM   9428  O  O    . ILE A 1 615 ? 17.735  22.709  28.724  1   44.72   ? 621  ILE A O    1 ? 
ATOM   9429  C  CB   . ILE A 1 615 ? 17.303  20.632  25.867  1   35.831  ? 621  ILE A CB   1 ? 
ATOM   9430  C  CG1  . ILE A 1 615 ? 18.082  19.622  26.687  1   36.478  ? 621  ILE A CG1  1 ? 
ATOM   9431  C  CG2  . ILE A 1 615 ? 17.722  20.598  24.387  1   34.637  ? 621  ILE A CG2  1 ? 
ATOM   9432  C  CD1  . ILE A 1 615 ? 18.032  18.202  26.155  1   35.905  ? 621  ILE A CD1  1 ? 
ATOM   9433  H  H    . ILE A 1 615 ? 19.415  22.169  26.907  1   41.715  ? 621  ILE A H    1 c 
ATOM   9434  H  HA   . ILE A 1 615 ? 16.86   22.643  25.902  1   40.829  ? 621  ILE A HA   1 c 
ATOM   9435  H  HB   . ILE A 1 615 ? 16.363  20.377  25.911  1   36.727  ? 621  ILE A HB   1 c 
ATOM   9436  H  HG12 . ILE A 1 615 ? 19.017  19.906  26.728  1   36.264  ? 621  ILE A HG12 1 c 
ATOM   9437  H  HG13 . ILE A 1 615 ? 17.73   19.622  27.6    1   36.264  ? 621  ILE A HG13 1 c 
ATOM   9438  H  HG21 . ILE A 1 615 ? 17.498  19.734  24.002  1   35.009  ? 621  ILE A HG21 1 c 
ATOM   9439  H  HG22 . ILE A 1 615 ? 18.679  20.745  24.315  1   35.049  ? 621  ILE A HG22 1 c 
ATOM   9440  H  HG23 . ILE A 1 615 ? 17.252  21.296  23.9    1   35      ? 621  ILE A HG23 1 c 
ATOM   9441  H  HD11 . ILE A 1 615 ? 17.108  17.959  25.958  1   36.069  ? 621  ILE A HD11 1 c 
ATOM   9442  H  HD12 . ILE A 1 615 ? 18.391  17.591  26.827  1   36.07   ? 621  ILE A HD12 1 c 
ATOM   9443  H  HD13 . ILE A 1 615 ? 18.566  18.133  25.34   1   36.058  ? 621  ILE A HD13 1 c 
ATOM   9444  N  N    . TYR A 1 616 ? 15.723  21.85   28.201  1   44.136  ? 622  TYR A N    1 ? 
ATOM   9445  C  CA   . TYR A 1 616 ? 15.171  22.046  29.531  1   42.095  ? 622  TYR A CA   1 ? 
ATOM   9446  C  C    . TYR A 1 616 ? 14.507  20.777  30.042  1   41.909  ? 622  TYR A C    1 ? 
ATOM   9447  O  O    . TYR A 1 616 ? 13.933  20.037  29.251  1   44.126  ? 622  TYR A O    1 ? 
ATOM   9448  C  CB   . TYR A 1 616 ? 14.175  23.199  29.498  1   40.456  ? 622  TYR A CB   1 ? 
ATOM   9449  C  CG   . TYR A 1 616 ? 14.81   24.444  28.897  1   44.7    ? 622  TYR A CG   1 ? 
ATOM   9450  C  CD1  . TYR A 1 616 ? 15.64   25.262  29.657  1   50.035  ? 622  TYR A CD1  1 ? 
ATOM   9451  C  CD2  . TYR A 1 616 ? 14.61   24.782  27.562  1   44.415  ? 622  TYR A CD2  1 ? 
ATOM   9452  C  CE1  . TYR A 1 616 ? 16.245  26.379  29.114  1   43.97   ? 622  TYR A CE1  1 ? 
ATOM   9453  C  CE2  . TYR A 1 616 ? 15.205  25.907  27.009  1   46.047  ? 622  TYR A CE2  1 ? 
ATOM   9454  C  CZ   . TYR A 1 616 ? 16.02   26.703  27.792  1   45.646  ? 622  TYR A CZ   1 ? 
ATOM   9455  O  OH   . TYR A 1 616 ? 16.612  27.817  27.296  1   50.347  ? 622  TYR A OH   1 ? 
ATOM   9456  H  H    . TYR A 1 616 ? 15.192  21.484  27.554  1   43.776  ? 622  TYR A H    1 c 
ATOM   9457  H  HA   . TYR A 1 616 ? 15.909  22.286  30.147  1   42.266  ? 622  TYR A HA   1 c 
ATOM   9458  H  HB2  . TYR A 1 616 ? 13.397  22.936  28.959  1   41.782  ? 622  TYR A HB2  1 c 
ATOM   9459  H  HB3  . TYR A 1 616 ? 13.879  23.393  30.414  1   41.878  ? 622  TYR A HB3  1 c 
ATOM   9460  H  HD1  . TYR A 1 616 ? 15.799  25.046  30.562  1   47.216  ? 622  TYR A HD1  1 c 
ATOM   9461  H  HD2  . TYR A 1 616 ? 14.056  24.241  27.025  1   44.813  ? 622  TYR A HD2  1 c 
ATOM   9462  H  HE1  . TYR A 1 616 ? 16.793  26.929  29.648  1   45.725  ? 622  TYR A HE1  1 c 
ATOM   9463  H  HE2  . TYR A 1 616 ? 15.056  26.127  26.107  1   45.604  ? 622  TYR A HE2  1 c 
ATOM   9464  H  HH   . TYR A 1 616 ? 17.384  27.597  26.958  0   50.81   ? 622  TYR A HH   1 c 
ATOM   9465  N  N    . ARG A 1 617 ? 14.59   20.554  31.375  1   48.268  ? 623  ARG A N    1 ? 
ATOM   9466  C  CA   . ARG A 1 617 ? 13.761  19.559  32.048  1   44.307  ? 623  ARG A CA   1 ? 
ATOM   9467  C  C    . ARG A 1 617 ? 12.718  20.266  32.915  1   42.653  ? 623  ARG A C    1 ? 
ATOM   9468  O  O    . ARG A 1 617 ? 13.061  21.08   33.758  1   41.122  ? 623  ARG A O    1 ? 
ATOM   9469  C  CB   . ARG A 1 617 ? 14.543  18.57   32.908  1   45.886  ? 623  ARG A CB   1 ? 
ATOM   9470  C  CG   . ARG A 1 617 ? 13.629  17.464  33.426  1   48.562  ? 623  ARG A CG   1 ? 
ATOM   9471  C  CD   . ARG A 1 617 ? 14.379  16.335  34.103  1   44.742  ? 623  ARG A CD   1 ? 
ATOM   9472  N  NE   . ARG A 1 617 ? 14.968  16.826  35.353  1   47.973  ? 623  ARG A NE   1 ? 
ATOM   9473  C  CZ   . ARG A 1 617 ? 15.543  16.076  36.263  1   44.721  ? 623  ARG A CZ   1 ? 
ATOM   9474  N  NH1  . ARG A 1 617 ? 15.451  14.768  36.25   1   48.469  ? 623  ARG A NH1  1 ? 
ATOM   9475  N  NH2  . ARG A 1 617 ? 16.164  16.657  37.252  1   50.828  ? 623  ARG A NH2  1 ? 
ATOM   9476  H  H    . ARG A 1 617 ? 15.184  21.039  31.874  1   45.722  ? 623  ARG A H    1 c 
ATOM   9477  H  HA   . ARG A 1 617 ? 13.285  19.037  31.354  1   44.978  ? 623  ARG A HA   1 c 
ATOM   9478  H  HB2  . ARG A 1 617 ? 15.265  18.173  32.377  1   46.055  ? 623  ARG A HB2  1 c 
ATOM   9479  H  HB3  . ARG A 1 617 ? 14.945  19.044  33.667  1   46.086  ? 623  ARG A HB3  1 c 
ATOM   9480  H  HG2  . ARG A 1 617 ? 12.991  17.847  34.067  1   47.024  ? 623  ARG A HG2  1 c 
ATOM   9481  H  HG3  . ARG A 1 617 ? 13.113  17.097  32.675  1   47.032  ? 623  ARG A HG3  1 c 
ATOM   9482  H  HD2  . ARG A 1 617 ? 13.766  15.599  34.295  1   46.263  ? 623  ARG A HD2  1 c 
ATOM   9483  H  HD3  . ARG A 1 617 ? 15.088  16.003  33.515  1   46.316  ? 623  ARG A HD3  1 c 
ATOM   9484  H  HE   . ARG A 1 617 ? 14.928  17.681  35.512  1   46.489  ? 623  ARG A HE   1 c 
ATOM   9485  H  HH11 . ARG A 1 617 ? 14.918  14.358  35.677  1   47.27   ? 623  ARG A HH11 1 c 
ATOM   9486  H  HH12 . ARG A 1 617 ? 15.928  14.291  36.824  1   47.318  ? 623  ARG A HH12 1 c 
ATOM   9487  H  HH21 . ARG A 1 617 ? 16.555  17.445  37.125  1   48.874  ? 623  ARG A HH21 1 c 
ATOM   9488  H  HH22 . ARG A 1 617 ? 16.194  16.259  38.047  1   48.85   ? 623  ARG A HH22 1 c 
ATOM   9489  N  N    . ILE A 1 618 ? 11.441  19.993  32.632  1   41.582  ? 624  ILE A N    1 ? 
ATOM   9490  C  CA   . ILE A 1 618 ? 10.331  20.393  33.477  1   44.026  ? 624  ILE A CA   1 ? 
ATOM   9491  C  C    . ILE A 1 618 ? 10.183  19.309  34.534  1   43.014  ? 624  ILE A C    1 ? 
ATOM   9492  O  O    . ILE A 1 618 ? 9.799   18.195  34.209  1   43.62   ? 624  ILE A O    1 ? 
ATOM   9493  C  CB   . ILE A 1 618 ? 9.014   20.582  32.689  1   45.216  ? 624  ILE A CB   1 ? 
ATOM   9494  C  CG1  . ILE A 1 618 ? 9.174   21.553  31.529  1   42.753  ? 624  ILE A CG1  1 ? 
ATOM   9495  C  CG2  . ILE A 1 618 ? 7.859   21.009  33.602  1   44.986  ? 624  ILE A CG2  1 ? 
ATOM   9496  C  CD1  . ILE A 1 618 ? 8.089   21.438  30.483  1   44.697  ? 624  ILE A CD1  1 ? 
ATOM   9497  H  H    . ILE A 1 618 ? 11.252  19.53   31.867  1   42.427  ? 624  ILE A H    1 c 
ATOM   9498  H  HA   . ILE A 1 618 ? 10.556  21.237  33.912  1   43.468  ? 624  ILE A HA   1 c 
ATOM   9499  H  HB   . ILE A 1 618 ? 8.778   19.713  32.307  1   44.462  ? 624  ILE A HB   1 c 
ATOM   9500  H  HG12 . ILE A 1 618 ? 9.175   22.466  31.882  1   43.743  ? 624  ILE A HG12 1 c 
ATOM   9501  H  HG13 . ILE A 1 618 ? 10.04   21.396  31.101  1   43.727  ? 624  ILE A HG13 1 c 
ATOM   9502  H  HG21 . ILE A 1 618 ? 7.06    21.16   33.07   1   45.023  ? 624  ILE A HG21 1 c 
ATOM   9503  H  HG22 . ILE A 1 618 ? 8.096   21.83   34.064  1   45.044  ? 624  ILE A HG22 1 c 
ATOM   9504  H  HG23 . ILE A 1 618 ? 7.682   20.312  34.254  1   45.036  ? 624  ILE A HG23 1 c 
ATOM   9505  H  HD11 . ILE A 1 618 ? 8.224   20.617  29.971  1   44.115  ? 624  ILE A HD11 1 c 
ATOM   9506  H  HD12 . ILE A 1 618 ? 8.136   22.205  29.881  1   44.116  ? 624  ILE A HD12 1 c 
ATOM   9507  H  HD13 . ILE A 1 618 ? 7.211   21.412  30.906  1   44.132  ? 624  ILE A HD13 1 c 
ATOM   9508  N  N    . ALA A 1 619 ? 10.468  19.68   35.789  1   39.112  ? 625  ALA A N    1 ? 
ATOM   9509  C  CA   . ALA A 1 619 ? 10.3    18.81   36.934  1   44.224  ? 625  ALA A CA   1 ? 
ATOM   9510  C  C    . ALA A 1 619 ? 9.009   19.202  37.644  1   44.858  ? 625  ALA A C    1 ? 
ATOM   9511  O  O    . ALA A 1 619 ? 8.845   20.36   38.037  1   42.71   ? 625  ALA A O    1 ? 
ATOM   9512  C  CB   . ALA A 1 619 ? 11.521  18.908  37.841  1   39.315  ? 625  ALA A CB   1 ? 
ATOM   9513  H  H    . ALA A 1 619 ? 10.787  20.524  35.933  1   41.18   ? 625  ALA A H    1 c 
ATOM   9514  H  HA   . ALA A 1 619 ? 10.211  17.872  36.609  1   42.423  ? 625  ALA A HA   1 c 
ATOM   9515  H  HB1  . ALA A 1 619 ? 12.315  18.634  37.351  1   40.713  ? 625  ALA A HB1  1 c 
ATOM   9516  H  HB2  . ALA A 1 619 ? 11.631  19.825  38.142  1   40.752  ? 625  ALA A HB2  1 c 
ATOM   9517  H  HB3  . ALA A 1 619 ? 11.403  18.329  38.612  1   40.713  ? 625  ALA A HB3  1 c 
ATOM   9518  N  N    . LEU A 1 620 ? 8.071   18.239  37.722  1   50.157  ? 626  LEU A N    1 ? 
ATOM   9519  C  CA   . LEU A 1 620 ? 6.842   18.376  38.498  1   47.742  ? 626  LEU A CA   1 ? 
ATOM   9520  C  C    . LEU A 1 620 ? 6.978   17.502  39.744  1   52.876  ? 626  LEU A C    1 ? 
ATOM   9521  O  O    . LEU A 1 620 ? 6.97    16.273  39.619  1   55.876  ? 626  LEU A O    1 ? 
ATOM   9522  C  CB   . LEU A 1 620 ? 5.59    17.993  37.71   1   50.579  ? 626  LEU A CB   1 ? 
ATOM   9523  C  CG   . LEU A 1 620 ? 5.45    18.612  36.32   1   45.369  ? 626  LEU A CG   1 ? 
ATOM   9524  C  CD1  . LEU A 1 620 ? 4.193   18.092  35.6    1   46.839  ? 626  LEU A CD1  1 ? 
ATOM   9525  C  CD2  . LEU A 1 620 ? 5.416   20.115  36.46   1   44.702  ? 626  LEU A CD2  1 ? 
ATOM   9526  H  H    . LEU A 1 620 ? 8.205   17.459  37.264  1   48.212  ? 626  LEU A H    1 c 
ATOM   9527  H  HA   . LEU A 1 620 ? 6.762   19.319  38.786  1   49.553  ? 626  LEU A HA   1 c 
ATOM   9528  H  HB2  . LEU A 1 620 ? 5.574   17.013  37.614  1   48.749  ? 626  LEU A HB2  1 c 
ATOM   9529  H  HB3  . LEU A 1 620 ? 4.803   18.251  38.244  1   48.668  ? 626  LEU A HB3  1 c 
ATOM   9530  H  HG   . LEU A 1 620 ? 6.246   18.363  35.783  1   46.449  ? 626  LEU A HG   1 c 
ATOM   9531  H  HD11 . LEU A 1 620 ? 4.191   17.12   35.612  1   46.383  ? 626  LEU A HD11 1 c 
ATOM   9532  H  HD12 . LEU A 1 620 ? 4.192   18.404  34.68   1   46.4    ? 626  LEU A HD12 1 c 
ATOM   9533  H  HD13 . LEU A 1 620 ? 3.399   18.421  36.054  1   46.4    ? 626  LEU A HD13 1 c 
ATOM   9534  H  HD21 . LEU A 1 620 ? 6.281   20.434  36.768  1   44.944  ? 626  LEU A HD21 1 c 
ATOM   9535  H  HD22 . LEU A 1 620 ? 4.732   20.366  37.103  1   44.909  ? 626  LEU A HD22 1 c 
ATOM   9536  H  HD23 . LEU A 1 620 ? 5.213   20.517  35.599  1   44.91   ? 626  LEU A HD23 1 c 
ATOM   9537  N  N    . LYS A 1 621 ? 7.105   18.139  40.929  1   52.213  ? 627  LYS A N    1 ? 
ATOM   9538  C  CA   . LYS A 1 621 ? 7.266   17.421  42.19   1   51.079  ? 627  LYS A CA   1 ? 
ATOM   9539  C  C    . LYS A 1 621 ? 5.983   17.501  43.019  1   41.362  ? 627  LYS A C    1 ? 
ATOM   9540  O  O    . LYS A 1 621 ? 5.519   18.578  43.372  1   42.239  ? 627  LYS A O    1 ? 
ATOM   9541  C  CB   . LYS A 1 621 ? 8.453   17.945  43.016  1   59.992  ? 627  LYS A CB   1 ? 
ATOM   9542  C  CG   . LYS A 1 621 ? 9.398   16.815  43.432  1   61.728  ? 627  LYS A CG   1 ? 
ATOM   9543  C  CD   . LYS A 1 621 ? 9.785   16.695  44.901  1   67.256  ? 627  LYS A CD   1 ? 
ATOM   9544  C  CE   . LYS A 1 621 ? 10.399  15.339  45.098  1   71.326  ? 627  LYS A CE   1 ? 
ATOM   9545  N  NZ   . LYS A 1 621 ? 10.849  15.089  46.466  1   74.681  ? 627  LYS A NZ   1 ? 
ATOM   9546  H  H    . LYS A 1 621 ? 7.09    19.053  40.946  1   52.059  ? 627  LYS A H    1 c 
ATOM   9547  H  HA   . LYS A 1 621 ? 7.436   16.47   41.978  1   50.931  ? 627  LYS A HA   1 c 
ATOM   9548  H  HB2  . LYS A 1 621 ? 8.955   18.599  42.485  1   58.153  ? 627  LYS A HB2  1 c 
ATOM   9549  H  HB3  . LYS A 1 621 ? 8.122   18.395  43.822  1   58.008  ? 627  LYS A HB3  1 c 
ATOM   9550  H  HG2  . LYS A 1 621 ? 8.991   15.966  43.155  1   62.455  ? 627  LYS A HG2  1 c 
ATOM   9551  H  HG3  . LYS A 1 621 ? 10.223  16.912  42.908  1   62.525  ? 627  LYS A HG3  1 c 
ATOM   9552  H  HD2  . LYS A 1 621 ? 10.436  17.391  45.137  1   66.87   ? 627  LYS A HD2  1 c 
ATOM   9553  H  HD3  . LYS A 1 621 ? 8.989   16.783  45.469  1   66.87   ? 627  LYS A HD3  1 c 
ATOM   9554  H  HE2  . LYS A 1 621 ? 9.755   14.652  44.85   1   70.723  ? 627  LYS A HE2  1 c 
ATOM   9555  H  HE3  . LYS A 1 621 ? 11.165  15.254  44.502  1   70.847  ? 627  LYS A HE3  1 c 
ATOM   9556  H  HZ1  . LYS A 1 621 ? 10.217  15.353  47.059  1   73.398  ? 627  LYS A HZ1  1 c 
ATOM   9557  H  HZ2  . LYS A 1 621 ? 11.61   15.557  46.624  1   73.562  ? 627  LYS A HZ2  1 c 
ATOM   9558  H  HZ3  . LYS A 1 621 ? 11.018  14.207  46.576  1   73.498  ? 627  LYS A HZ3  1 c 
ATOM   9559  N  N    . ASP A 1 622 ? 5.384   16.338  43.289  1   46.829  ? 628  ASP A N    1 ? 
ATOM   9560  C  CA   . ASP A 1 622 ? 4.145   16.272  44.049  1   46.871  ? 628  ASP A CA   1 ? 
ATOM   9561  C  C    . ASP A 1 622 ? 4.414   16.893  45.422  1   45.766  ? 628  ASP A C    1 ? 
ATOM   9562  O  O    . ASP A 1 622 ? 5.367   16.518  46.089  1   45.968  ? 628  ASP A O    1 ? 
ATOM   9563  C  CB   . ASP A 1 622 ? 3.652   14.831  44.109  1   42.01   ? 628  ASP A CB   1 ? 
ATOM   9564  C  CG   . ASP A 1 622 ? 2.244   14.635  44.638  1   46.541  ? 628  ASP A CG   1 ? 
ATOM   9565  O  OD1  . ASP A 1 622 ? 1.701   15.623  45.148  1   49.36   ? 628  ASP A OD1  1 ? 
ATOM   9566  O  OD2  . ASP A 1 622 ? 1.681   13.508  44.496  1   50.097  ? 628  ASP A OD2  1 ? 
ATOM   9567  H  H    . ASP A 1 622 ? 5.76    15.56   42.992  1   45.519  ? 628  ASP A H    1 c 
ATOM   9568  H  HA   . ASP A 1 622 ? 3.468   16.811  43.581  1   45.73   ? 628  ASP A HA   1 c 
ATOM   9569  H  HB2  . ASP A 1 622 ? 3.689   14.451  43.206  1   44.109  ? 628  ASP A HB2  1 c 
ATOM   9570  H  HB3  . ASP A 1 622 ? 4.263   14.316  44.676  1   44.102  ? 628  ASP A HB3  1 c 
ATOM   9571  N  N    . LYS A 1 623 ? 3.606   17.869  45.828  1   44.759  ? 629  LYS A N    1 ? 
ATOM   9572  C  CA   . LYS A 1 623 ? 3.755   18.479  47.149  1   53.59   ? 629  LYS A CA   1 ? 
ATOM   9573  C  C    . LYS A 1 623 ? 3.751   17.474  48.308  1   51.469  ? 629  LYS A C    1 ? 
ATOM   9574  O  O    . LYS A 1 623 ? 4.431   17.732  49.295  1   58.996  ? 629  LYS A O    1 ? 
ATOM   9575  C  CB   . LYS A 1 623 ? 2.662   19.514  47.417  1   57.502  ? 629  LYS A CB   1 ? 
ATOM   9576  C  CG   . LYS A 1 623 ? 2.882   20.809  46.671  1   63.301  ? 629  LYS A CG   1 ? 
ATOM   9577  C  CD   . LYS A 1 623 ? 1.658   21.717  46.628  1   66.639  ? 629  LYS A CD   1 ? 
ATOM   9578  C  CE   . LYS A 1 623 ? 1.815   22.729  45.534  1   70.781  ? 629  LYS A CE   1 ? 
ATOM   9579  N  NZ   . LYS A 1 623 ? 0.657   23.613  45.412  1   72      ? 629  LYS A NZ   1 ? 
ATOM   9580  H  H    . LYS A 1 623 ? 2.941   18.167  45.276  1   46.907  ? 629  LYS A H    1 c 
ATOM   9581  H  HA   . LYS A 1 623 ? 4.625   18.953  47.163  1   52.121  ? 629  LYS A HA   1 c 
ATOM   9582  H  HB2  . LYS A 1 623 ? 1.795   19.141  47.153  1   57.909  ? 629  LYS A HB2  1 c 
ATOM   9583  H  HB3  . LYS A 1 623 ? 2.629   19.708  48.379  1   57.834  ? 629  LYS A HB3  1 c 
ATOM   9584  H  HG2  . LYS A 1 623 ? 3.622   21.293  47.098  1   62.636  ? 629  LYS A HG2  1 c 
ATOM   9585  H  HG3  . LYS A 1 623 ? 3.156   20.597  45.752  1   62.623  ? 629  LYS A HG3  1 c 
ATOM   9586  H  HD2  . LYS A 1 623 ? 0.853   21.18   46.462  1   66.733  ? 629  LYS A HD2  1 c 
ATOM   9587  H  HD3  . LYS A 1 623 ? 1.56    22.18   47.488  1   66.784  ? 629  LYS A HD3  1 c 
ATOM   9588  H  HE2  . LYS A 1 623 ? 2.607   23.269  45.708  1   70.085  ? 629  LYS A HE2  1 c 
ATOM   9589  H  HE3  . LYS A 1 623 ? 1.947   22.268  44.686  1   70.043  ? 629  LYS A HE3  1 c 
ATOM   9590  H  HZ1  . LYS A 1 623 ? 0.532   24.061  46.189  1   71.623  ? 629  LYS A HZ1  1 c 
ATOM   9591  H  HZ2  . LYS A 1 623 ? -0.083  23.125  45.227  1   71.623  ? 629  LYS A HZ2  1 c 
ATOM   9592  H  HZ3  . LYS A 1 623 ? 0.796   24.209  44.744  1   71.623  ? 629  LYS A HZ3  1 c 
ATOM   9593  N  N    . ASP A 1 624 ? 2.98    16.371  48.237  1   53.992  ? 630  ASP A N    1 ? 
ATOM   9594  C  CA   . ASP A 1 624 ? 2.945   15.385  49.322  1   56.073  ? 630  ASP A CA   1 ? 
ATOM   9595  C  C    . ASP A 1 624 ? 3.073   13.961  48.796  1   61.024  ? 630  ASP A C    1 ? 
ATOM   9596  O  O    . ASP A 1 624 ? 2.649   13.635  47.682  1   59.716  ? 630  ASP A O    1 ? 
ATOM   9597  C  CB   . ASP A 1 624 ? 1.673   15.38   50.149  1   54.129  ? 630  ASP A CB   1 ? 
ATOM   9598  C  CG   . ASP A 1 624 ? 1.14    16.749  50.54   1   64.597  ? 630  ASP A CG   1 ? 
ATOM   9599  O  OD1  . ASP A 1 624 ? 0.634   17.458  49.642  1   72.456  ? 630  ASP A OD1  1 ? 
ATOM   9600  O  OD2  . ASP A 1 624 ? 1.234   17.094  51.737  1   82.488  ? 630  ASP A OD2  1 ? 
ATOM   9601  H  H    . ASP A 1 624 ? 2.461   16.231  47.498  1   53.723  ? 630  ASP A H    1 c 
ATOM   9602  H  HA   . ASP A 1 624 ? 3.699   15.562  49.928  1   56.111  ? 630  ASP A HA   1 c 
ATOM   9603  H  HB2  . ASP A 1 624 ? 0.969   14.92   49.646  1   56.891  ? 630  ASP A HB2  1 c 
ATOM   9604  H  HB3  . ASP A 1 624 ? 1.836   14.871  50.97   1   56.972  ? 630  ASP A HB3  1 c 
ATOM   9605  N  N    . ALA A 1 625 ? 3.642   13.105  49.643  1   51.863  ? 631  ALA A N    1 ? 
ATOM   9606  C  CA   . ALA A 1 625 ? 3.753   11.704  49.307  1   48.502  ? 631  ALA A CA   1 ? 
ATOM   9607  C  C    . ALA A 1 625 ? 2.396   11.044  49.553  1   53.837  ? 631  ALA A C    1 ? 
ATOM   9608  O  O    . ALA A 1 625 ? 1.695   11.441  50.483  1   44.778  ? 631  ALA A O    1 ? 
ATOM   9609  C  CB   . ALA A 1 625 ? 4.87    11.094  50.104  1   50.307  ? 631  ALA A CB   1 ? 
ATOM   9610  H  H    . ALA A 1 625 ? 3.966   13.4    50.445  1   53.13   ? 631  ALA A H    1 c 
ATOM   9611  H  HA   . ALA A 1 625 ? 3.968   11.629  48.337  1   50.513  ? 631  ALA A HA   1 c 
ATOM   9612  H  HB1  . ALA A 1 625 ? 5.678   11.623  49.993  1   49.766  ? 631  ALA A HB1  1 c 
ATOM   9613  H  HB2  . ALA A 1 625 ? 4.627   11.072  51.045  1   49.766  ? 631  ALA A HB2  1 c 
ATOM   9614  H  HB3  . ALA A 1 625 ? 5.036   10.188  49.794  1   49.781  ? 631  ALA A HB3  1 c 
ATOM   9615  N  N    . ARG A 1 626 ? 2.014   10.099  48.67   1   47.759  ? 632  ARG A N    1 ? 
ATOM   9616  C  CA   . ARG A 1 626 ? 0.732   9.415   48.724  1   48.712  ? 632  ARG A CA   1 ? 
ATOM   9617  C  C    . ARG A 1 626 ? 0.931   7.934   48.429  1   46.17   ? 632  ARG A C    1 ? 
ATOM   9618  O  O    . ARG A 1 626 ? 1.749   7.574   47.6    1   54.587  ? 632  ARG A O    1 ? 
ATOM   9619  C  CB   . ARG A 1 626 ? -0.281  9.956   47.703  1   57.933  ? 632  ARG A CB   1 ? 
ATOM   9620  C  CG   . ARG A 1 626 ? -1.176  11.059  48.249  1   68.517  ? 632  ARG A CG   1 ? 
ATOM   9621  C  CD   . ARG A 1 626 ? -2.275  11.552  47.27   1   77.897  ? 632  ARG A CD   1 ? 
ATOM   9622  N  NE   . ARG A 1 626 ? -2.048  12.984  47.044  1   68.035  ? 632  ARG A NE   1 ? 
ATOM   9623  C  CZ   . ARG A 1 626 ? -0.927  13.409  46.463  1   67.43   ? 632  ARG A CZ   1 ? 
ATOM   9624  N  NH1  . ARG A 1 626 ? -0.195  12.551  45.747  1   63.032  ? 632  ARG A NH1  1 ? 
ATOM   9625  N  NH2  . ARG A 1 626 ? -0.55   14.669  46.621  1   59.98   ? 632  ARG A NH2  1 ? 
ATOM   9626  H  H    . ARG A 1 626 ? 2.593   9.875   47.999  1   49.345  ? 632  ARG A H    1 c 
ATOM   9627  H  HA   . ARG A 1 626 ? 0.36    9.511   49.637  1   49.725  ? 632  ARG A HA   1 c 
ATOM   9628  H  HB2  . ARG A 1 626 ? 0.209   10.299  46.926  1   57.896  ? 632  ARG A HB2  1 c 
ATOM   9629  H  HB3  . ARG A 1 626 ? -0.847  9.216   47.395  1   57.815  ? 632  ARG A HB3  1 c 
ATOM   9630  H  HG2  . ARG A 1 626 ? -1.611  10.734  49.067  1   67.706  ? 632  ARG A HG2  1 c 
ATOM   9631  H  HG3  . ARG A 1 626 ? -0.614  11.821  48.508  1   67.812  ? 632  ARG A HG3  1 c 
ATOM   9632  H  HD2  . ARG A 1 626 ? -2.225  11.069  46.42   1   73.138  ? 632  ARG A HD2  1 c 
ATOM   9633  H  HD3  . ARG A 1 626 ? -3.164  11.416  47.658  1   73.308  ? 632  ARG A HD3  1 c 
ATOM   9634  H  HE   . ARG A 1 626 ? -2.653  13.559  47.292  1   69.878  ? 632  ARG A HE   1 c 
ATOM   9635  H  HH11 . ARG A 1 626 ? -0.564  12.112  45.073  1   64.492  ? 632  ARG A HH11 1 c 
ATOM   9636  H  HH12 . ARG A 1 626 ? 0.658   12.427  45.949  1   64.386  ? 632  ARG A HH12 1 c 
ATOM   9637  H  HH21 . ARG A 1 626 ? -1.078  15.236  47.046  1   62.259  ? 632  ARG A HH21 1 c 
ATOM   9638  H  HH22 . ARG A 1 626 ? 0.227   14.94   46.304  1   62.093  ? 632  ARG A HH22 1 c 
ATOM   9639  N  N    . LEU A 1 627 ? 0.125   7.085   49.071  1   45.644  ? 633  LEU A N    1 ? 
ATOM   9640  C  CA   . LEU A 1 627 ? 0.2     5.653   48.855  1   42.925  ? 633  LEU A CA   1 ? 
ATOM   9641  C  C    . LEU A 1 627 ? -0.371  5.293   47.498  1   44.991  ? 633  LEU A C    1 ? 
ATOM   9642  O  O    . LEU A 1 627 ? 0.165   4.377   46.872  1   44.833  ? 633  LEU A O    1 ? 
ATOM   9643  C  CB   . LEU A 1 627 ? -0.555  4.852   49.914  1   43.216  ? 633  LEU A CB   1 ? 
ATOM   9644  C  CG   . LEU A 1 627 ? 0.218   4.64    51.208  1   51.439  ? 633  LEU A CG   1 ? 
ATOM   9645  C  CD1  . LEU A 1 627 ? -0.739  4.141   52.293  1   52.926  ? 633  LEU A CD1  1 ? 
ATOM   9646  C  CD2  . LEU A 1 627 ? 1.358   3.663   50.94   1   53.556  ? 633  LEU A CD2  1 ? 
ATOM   9647  H  H    . LEU A 1 627 ? -0.49   7.41    49.663  1   45.183  ? 633  LEU A H    1 c 
ATOM   9648  H  HA   . LEU A 1 627 ? 1.154   5.391   48.869  1   44.046  ? 633  LEU A HA   1 c 
ATOM   9649  H  HB2  . LEU A 1 627 ? -1.394  5.324   50.122  1   45.009  ? 633  LEU A HB2  1 c 
ATOM   9650  H  HB3  . LEU A 1 627 ? -0.782  3.971   49.536  1   45.013  ? 633  LEU A HB3  1 c 
ATOM   9651  H  HG   . LEU A 1 627 ? 0.602   5.508   51.494  1   50.434  ? 633  LEU A HG   1 c 
ATOM   9652  H  HD11 . LEU A 1 627 ? -1.453  4.788   52.418  1   52.429  ? 633  LEU A HD11 1 c 
ATOM   9653  H  HD12 . LEU A 1 627 ? -0.253  4.031   53.128  1   52.472  ? 633  LEU A HD12 1 c 
ATOM   9654  H  HD13 . LEU A 1 627 ? -1.119  3.288   52.025  1   52.472  ? 633  LEU A HD13 1 c 
ATOM   9655  H  HD21 . LEU A 1 627 ? 2.002   4.068   50.336  1   52.764  ? 633  LEU A HD21 1 c 
ATOM   9656  H  HD22 . LEU A 1 627 ? 1.004   2.852   50.539  1   52.786  ? 633  LEU A HD22 1 c 
ATOM   9657  H  HD23 . LEU A 1 627 ? 1.798   3.442   51.778  1   52.866  ? 633  LEU A HD23 1 c 
ATOM   9658  N  N    . THR A 1 628 ? -1.529  5.895   47.16   1   40.336  ? 634  THR A N    1 ? 
ATOM   9659  C  CA   . THR A 1 628 ? -2.214  5.594   45.918  1   48.551  ? 634  THR A CA   1 ? 
ATOM   9660  C  C    . THR A 1 628 ? -2.647  6.923   45.321  1   46.418  ? 634  THR A C    1 ? 
ATOM   9661  O  O    . THR A 1 628 ? -2.873  7.893   46.023  1   47.885  ? 634  THR A O    1 ? 
ATOM   9662  C  CB   . THR A 1 628 ? -3.441  4.687   46.04   1   46.648  ? 634  THR A CB   1 ? 
ATOM   9663  O  OG1  . THR A 1 628 ? -4.355  5.59    46.641  1   52.003  ? 634  THR A OG1  1 ? 
ATOM   9664  C  CG2  . THR A 1 628 ? -3.233  3.416   46.837  1   45.521  ? 634  THR A CG2  1 ? 
ATOM   9665  H  H    . THR A 1 628 ? -1.903  6.503   47.732  1   43.207  ? 634  THR A H    1 c 
ATOM   9666  H  HA   . THR A 1 628 ? -1.575  5.171   45.308  1   46.043  ? 634  THR A HA   1 c 
ATOM   9667  H  HB   . THR A 1 628 ? -3.765  4.45    45.138  1   47.779  ? 634  THR A HB   1 c 
ATOM   9668  H  HG1  . THR A 1 628 ? -4.044  5.897   47.367  0   52.02   ? 634  THR A HG1  1 c 
ATOM   9669  H  HG21 . THR A 1 628 ? -4.053  2.895   46.838  1   45.845  ? 634  THR A HG21 1 c 
ATOM   9670  H  HG22 . THR A 1 628 ? -2.992  3.643   47.752  1   45.822  ? 634  THR A HG22 1 c 
ATOM   9671  H  HG23 . THR A 1 628 ? -2.518  2.894   46.436  1   45.845  ? 634  THR A HG23 1 c 
ATOM   9672  N  N    . GLY A 1 629 ? -2.793  6.953   44.005  1   45.979  ? 635  GLY A N    1 ? 
ATOM   9673  C  CA   . GLY A 1 629 ? -3.172  8.201   43.374  1   50.549  ? 635  GLY A CA   1 ? 
ATOM   9674  C  C    . GLY A 1 629 ? -3.251  8.067   41.866  1   43.492  ? 635  GLY A C    1 ? 
ATOM   9675  O  O    . GLY A 1 629 ? -2.895  7.033   41.299  1   45.036  ? 635  GLY A O    1 ? 
ATOM   9676  H  H    . GLY A 1 629 ? -2.66   6.205   43.497  1   47.051  ? 635  GLY A H    1 c 
ATOM   9677  H  HA2  . GLY A 1 629 ? -4.048  8.483   43.725  1   47.823  ? 635  GLY A HA2  1 c 
ATOM   9678  H  HA3  . GLY A 1 629 ? -2.512  8.895   43.609  1   47.784  ? 635  GLY A HA3  1 c 
ATOM   9679  N  N    . LYS A 1 630 ? -3.784  9.124   41.259  1   45.482  ? 636  LYS A N    1 ? 
ATOM   9680  C  CA   . LYS A 1 630 ? -3.958  9.199   39.821  1   51.049  ? 636  LYS A CA   1 ? 
ATOM   9681  C  C    . LYS A 1 630 ? -3.523  10.603  39.424  1   52.582  ? 636  LYS A C    1 ? 
ATOM   9682  O  O    . LYS A 1 630 ? -4.028  11.579  39.971  1   51.321  ? 636  LYS A O    1 ? 
ATOM   9683  C  CB   . LYS A 1 630 ? -5.39   8.851   39.392  1   57.133  ? 636  LYS A CB   1 ? 
ATOM   9684  C  CG   . LYS A 1 630 ? -5.645  9.015   37.9    1   70.838  ? 636  LYS A CG   1 ? 
ATOM   9685  C  CD   . LYS A 1 630 ? -7.015  8.593   37.381  1   75.739  ? 636  LYS A CD   1 ? 
ATOM   9686  C  CE   . LYS A 1 630 ? -7.03   8.563   35.878  1   76.211  ? 636  LYS A CE   1 ? 
ATOM   9687  N  NZ   . LYS A 1 630 ? -8.234  7.875   35.41   1   82.264  ? 636  LYS A NZ   1 ? 
ATOM   9688  H  H    . LYS A 1 630 ? -4.056  9.833   41.768  1   46.276  ? 636  LYS A H    1 c 
ATOM   9689  H  HA   . LYS A 1 630 ? -3.346  8.548   39.402  1   51.117  ? 636  LYS A HA   1 c 
ATOM   9690  H  HB2  . LYS A 1 630 ? -5.58   7.922   39.642  1   58.575  ? 636  LYS A HB2  1 c 
ATOM   9691  H  HB3  . LYS A 1 630 ? -6.017  9.426   39.881  1   58.532  ? 636  LYS A HB3  1 c 
ATOM   9692  H  HG2  . LYS A 1 630 ? -5.509  9.96    37.671  1   68.382  ? 636  LYS A HG2  1 c 
ATOM   9693  H  HG3  . LYS A 1 630 ? -4.96   8.503   37.419  1   68.522  ? 636  LYS A HG3  1 c 
ATOM   9694  H  HD2  . LYS A 1 630 ? -7.238  7.702   37.727  1   74.619  ? 636  LYS A HD2  1 c 
ATOM   9695  H  HD3  . LYS A 1 630 ? -7.694  9.228   37.699  1   74.692  ? 636  LYS A HD3  1 c 
ATOM   9696  H  HE2  . LYS A 1 630 ? -7.021  9.472   35.528  1   77.481  ? 636  LYS A HE2  1 c 
ATOM   9697  H  HE3  . LYS A 1 630 ? -6.244  8.094   35.545  1   77.43   ? 636  LYS A HE3  1 c 
ATOM   9698  H  HZ1  . LYS A 1 630 ? -8.971  8.303   35.719  1   80.309  ? 636  LYS A HZ1  1 c 
ATOM   9699  H  HZ2  . LYS A 1 630 ? -8.237  7.021   35.709  1   80.278  ? 636  LYS A HZ2  1 c 
ATOM   9700  H  HZ3  . LYS A 1 630 ? -8.251  7.873   34.504  1   80.33   ? 636  LYS A HZ3  1 c 
ATOM   9701  N  N    . TYR A 1 631 ? -2.525  10.703  38.542  1   50.307  ? 637  TYR A N    1 ? 
ATOM   9702  C  CA   . TYR A 1 631 ? -2.174  12      37.975  1   49.863  ? 637  TYR A CA   1 ? 
ATOM   9703  C  C    . TYR A 1 631 ? -2.674  12.063  36.539  1   45.268  ? 637  TYR A C    1 ? 
ATOM   9704  O  O    . TYR A 1 631 ? -2.583  11.078  35.817  1   45.538  ? 637  TYR A O    1 ? 
ATOM   9705  C  CB   . TYR A 1 631 ? -0.669  12.253  37.918  1   50.656  ? 637  TYR A CB   1 ? 
ATOM   9706  C  CG   . TYR A 1 631 ? 0.113   12.133  39.218  1   46.42   ? 637  TYR A CG   1 ? 
ATOM   9707  C  CD1  . TYR A 1 631 ? -0.327  12.738  40.394  1   41.983  ? 637  TYR A CD1  1 ? 
ATOM   9708  C  CD2  . TYR A 1 631 ? 1.311   11.423  39.249  1   44.413  ? 637  TYR A CD2  1 ? 
ATOM   9709  C  CE1  . TYR A 1 631 ? 0.423   12.648  41.558  1   47.458  ? 637  TYR A CE1  1 ? 
ATOM   9710  C  CE2  . TYR A 1 631 ? 2.073   11.339  40.404  1   46.958  ? 637  TYR A CE2  1 ? 
ATOM   9711  C  CZ   . TYR A 1 631 ? 1.622   11.945  41.565  1   50.634  ? 637  TYR A CZ   1 ? 
ATOM   9712  O  OH   . TYR A 1 631 ? 2.398   11.842  42.68   1   50.321  ? 637  TYR A OH   1 ? 
ATOM   9713  H  H    . TYR A 1 631 ? -2.053  9.962   38.291  1   50.704  ? 637  TYR A H    1 c 
ATOM   9714  H  HA   . TYR A 1 631 ? -2.605  12.721  38.506  1   49.232  ? 637  TYR A HA   1 c 
ATOM   9715  H  HB2  . TYR A 1 631 ? -0.282  11.627  37.267  1   49.312  ? 637  TYR A HB2  1 c 
ATOM   9716  H  HB3  . TYR A 1 631 ? -0.528  13.156  37.558  1   49.42   ? 637  TYR A HB3  1 c 
ATOM   9717  H  HD1  . TYR A 1 631 ? -1.133  13.229  40.395  1   44.318  ? 637  TYR A HD1  1 c 
ATOM   9718  H  HD2  . TYR A 1 631 ? 1.631   11.021  38.457  1   45.548  ? 637  TYR A HD2  1 c 
ATOM   9719  H  HE1  . TYR A 1 631 ? 0.12    13.067  42.346  1   46.841  ? 637  TYR A HE1  1 c 
ATOM   9720  H  HE2  . TYR A 1 631 ? 2.884   10.858  40.406  1   47.163  ? 637  TYR A HE2  1 c 
ATOM   9721  H  HH   . TYR A 1 631 ? 2.163   11.128  43.126  0   50.51   ? 637  TYR A HH   1 c 
ATOM   9722  N  N    . LYS A 1 632 ? -3.189  13.22   36.13   1   48.622  ? 638  LYS A N    1 ? 
ATOM   9723  C  CA   . LYS A 1 632 ? -3.679  13.391  34.772  1   48.025  ? 638  LYS A CA   1 ? 
ATOM   9724  C  C    . LYS A 1 632 ? -3.045  14.643  34.183  1   49.109  ? 638  LYS A C    1 ? 
ATOM   9725  O  O    . LYS A 1 632 ? -3.12   15.696  34.803  1   42.906  ? 638  LYS A O    1 ? 
ATOM   9726  C  CB   . LYS A 1 632 ? -5.203  13.471  34.762  1   46.322  ? 638  LYS A CB   1 ? 
ATOM   9727  C  CG   . LYS A 1 632 ? -5.746  13.783  33.392  1   53.837  ? 638  LYS A CG   1 ? 
ATOM   9728  C  CD   . LYS A 1 632 ? -7.259  13.714  33.306  1   57.642  ? 638  LYS A CD   1 ? 
ATOM   9729  C  CE   . LYS A 1 632 ? -7.743  14.937  32.603  1   64.88   ? 638  LYS A CE   1 ? 
ATOM   9730  N  NZ   . LYS A 1 632 ? -9.114  14.755  32.133  1   70.468  ? 638  LYS A NZ   1 ? 
ATOM   9731  H  H    . LYS A 1 632 ? -3.238  13.925  36.71   1   47.704  ? 638  LYS A H    1 c 
ATOM   9732  H  HA   . LYS A 1 632 ? -3.4    12.609  34.234  1   47.95   ? 638  LYS A HA   1 c 
ATOM   9733  H  HB2  . LYS A 1 632 ? -5.574  12.614  35.063  1   48.352  ? 638  LYS A HB2  1 c 
ATOM   9734  H  HB3  . LYS A 1 632 ? -5.496  14.168  35.387  1   48.357  ? 638  LYS A HB3  1 c 
ATOM   9735  H  HG2  . LYS A 1 632 ? -5.451  14.684  33.138  1   52.938  ? 638  LYS A HG2  1 c 
ATOM   9736  H  HG3  . LYS A 1 632 ? -5.359  13.148  32.75   1   52.837  ? 638  LYS A HG3  1 c 
ATOM   9737  H  HD2  . LYS A 1 632 ? -7.53   12.915  32.803  1   58.385  ? 638  LYS A HD2  1 c 
ATOM   9738  H  HD3  . LYS A 1 632 ? -7.647  13.677  34.207  1   58.272  ? 638  LYS A HD3  1 c 
ATOM   9739  H  HE2  . LYS A 1 632 ? -7.712  15.699  33.209  1   64.365  ? 638  LYS A HE2  1 c 
ATOM   9740  H  HE3  . LYS A 1 632 ? -7.174  15.13   31.836  1   64.244  ? 638  LYS A HE3  1 c 
ATOM   9741  H  HZ1  . LYS A 1 632 ? -9.656  14.564  32.834  1   68.612  ? 638  LYS A HZ1  1 c 
ATOM   9742  H  HZ2  . LYS A 1 632 ? -9.147  14.073  31.537  1   68.606  ? 638  LYS A HZ2  1 c 
ATOM   9743  H  HZ3  . LYS A 1 632 ? -9.404  15.514  31.732  1   68.664  ? 638  LYS A HZ3  1 c 
ATOM   9744  N  N    . PHE A 1 633 ? -2.38   14.491  33.02   1   50.17   ? 639  PHE A N    1 ? 
ATOM   9745  C  CA   . PHE A 1 633 ? -1.765  15.606  32.326  1   43.704  ? 639  PHE A CA   1 ? 
ATOM   9746  C  C    . PHE A 1 633 ? -2.471  15.764  30.986  1   46.151  ? 639  PHE A C    1 ? 
ATOM   9747  O  O    . PHE A 1 633 ? -2.775  14.772  30.344  1   48.113  ? 639  PHE A O    1 ? 
ATOM   9748  C  CB   . PHE A 1 633 ? -0.26   15.405  32.123  1   47.019  ? 639  PHE A CB   1 ? 
ATOM   9749  C  CG   . PHE A 1 633 ? 0.485   15.064  33.407  1   45.149  ? 639  PHE A CG   1 ? 
ATOM   9750  C  CD1  . PHE A 1 633 ? 0.879   16.056  34.289  1   47.092  ? 639  PHE A CD1  1 ? 
ATOM   9751  C  CD2  . PHE A 1 633 ? 0.763   13.75   33.736  1   41.48   ? 639  PHE A CD2  1 ? 
ATOM   9752  C  CE1  . PHE A 1 633 ? 1.549   15.734  35.454  1   50.979  ? 639  PHE A CE1  1 ? 
ATOM   9753  C  CE2  . PHE A 1 633 ? 1.445   13.438  34.889  1   41.381  ? 639  PHE A CE2  1 ? 
ATOM   9754  C  CZ   . PHE A 1 633 ? 1.816   14.426  35.759  1   43.574  ? 639  PHE A CZ   1 ? 
ATOM   9755  H  H    . PHE A 1 633 ? -2.312  13.657  32.652  1   48.371  ? 639  PHE A H    1 c 
ATOM   9756  H  HA   . PHE A 1 633 ? -1.905  16.43   32.86   1   45.929  ? 639  PHE A HA   1 c 
ATOM   9757  H  HB2  . PHE A 1 633 ? -0.125  14.682  31.473  1   45.761  ? 639  PHE A HB2  1 c 
ATOM   9758  H  HB3  . PHE A 1 633 ? 0.116   16.228  31.744  1   45.951  ? 639  PHE A HB3  1 c 
ATOM   9759  H  HD1  . PHE A 1 633 ? 0.692   16.96   34.09   1   47.379  ? 639  PHE A HD1  1 c 
ATOM   9760  H  HD2  . PHE A 1 633 ? 0.506   13.06   33.145  1   42.384  ? 639  PHE A HD2  1 c 
ATOM   9761  H  HE1  . PHE A 1 633 ? 1.815   16.418  36.047  1   48.109  ? 639  PHE A HE1  1 c 
ATOM   9762  H  HE2  . PHE A 1 633 ? 1.624   12.537  35.097  1   41.947  ? 639  PHE A HE2  1 c 
ATOM   9763  H  HZ   . PHE A 1 633 ? 2.281   14.209  36.552  1   44.666  ? 639  PHE A HZ   1 c 
ATOM   9764  N  N    . VAL A 1 634 ? -2.704  17.017  30.572  1   44.829  ? 640  VAL A N    1 ? 
ATOM   9765  C  CA   . VAL A 1 634 ? -3.314  17.325  29.293  1   45.432  ? 640  VAL A CA   1 ? 
ATOM   9766  C  C    . VAL A 1 634 ? -2.387  18.268  28.515  1   46.934  ? 640  VAL A C    1 ? 
ATOM   9767  O  O    . VAL A 1 634 ? -2.011  19.335  29.002  1   38.413  ? 640  VAL A O    1 ? 
ATOM   9768  C  CB   . VAL A 1 634 ? -4.703  17.973  29.464  1   54.317  ? 640  VAL A CB   1 ? 
ATOM   9769  C  CG1  . VAL A 1 634 ? -5.432  18.08   28.129  1   54.07   ? 640  VAL A CG1  1 ? 
ATOM   9770  C  CG2  . VAL A 1 634 ? -5.569  17.249  30.488  1   59.098  ? 640  VAL A CG2  1 ? 
ATOM   9771  H  H    . VAL A 1 634 ? -2.468  17.712  31.117  1   45.272  ? 640  VAL A H    1 c 
ATOM   9772  H  HA   . VAL A 1 634 ? -3.417  16.497  28.787  1   47.036  ? 640  VAL A HA   1 c 
ATOM   9773  H  HB   . VAL A 1 634 ? -4.555  18.89   29.796  1   53.214  ? 640  VAL A HB   1 c 
ATOM   9774  H  HG11 . VAL A 1 634 ? -5.488  17.201  27.718  1   54.139  ? 640  VAL A HG11 1 c 
ATOM   9775  H  HG12 . VAL A 1 634 ? -4.947  18.682  27.54   1   54.109  ? 640  VAL A HG12 1 c 
ATOM   9776  H  HG13 . VAL A 1 634 ? -6.328  18.425  28.276  1   54.156  ? 640  VAL A HG13 1 c 
ATOM   9777  H  HG21 . VAL A 1 634 ? -6.457  17.642  30.498  1   57.603  ? 640  VAL A HG21 1 c 
ATOM   9778  H  HG22 . VAL A 1 634 ? -5.169  17.333  31.37   1   57.558  ? 640  VAL A HG22 1 c 
ATOM   9779  H  HG23 . VAL A 1 634 ? -5.634  16.308  30.251  1   57.622  ? 640  VAL A HG23 1 c 
ATOM   9780  N  N    . ILE A 1 635 ? -2.055  17.874  27.28   1   41.635  ? 641  ILE A N    1 ? 
ATOM   9781  C  CA   . ILE A 1 635 ? -1.284  18.718  26.377  1   48.61   ? 641  ILE A CA   1 ? 
ATOM   9782  C  C    . ILE A 1 635 ? -2.156  19.102  25.182  1   43.746  ? 641  ILE A C    1 ? 
ATOM   9783  O  O    . ILE A 1 635 ? -2.623  18.216  24.466  1   43.761  ? 641  ILE A O    1 ? 
ATOM   9784  C  CB   . ILE A 1 635 ? -0.01   17.982  25.924  1   47.348  ? 641  ILE A CB   1 ? 
ATOM   9785  C  CG1  . ILE A 1 635 ? 0.857   17.613  27.134  1   40.54   ? 641  ILE A CG1  1 ? 
ATOM   9786  C  CG2  . ILE A 1 635 ? 0.771   18.794  24.881  1   47.08   ? 641  ILE A CG2  1 ? 
ATOM   9787  C  CD1  . ILE A 1 635 ? 2.097   16.837  26.738  1   42.758  ? 641  ILE A CD1  1 ? 
ATOM   9788  H  H    . ILE A 1 635 ? -2.318  17.049  26.988  1   44.395  ? 641  ILE A H    1 c 
ATOM   9789  H  HA   . ILE A 1 635 ? -1.021  19.525  26.85   1   45.954  ? 641  ILE A HA   1 c 
ATOM   9790  H  HB   . ILE A 1 635 ? -0.29   17.147  25.5    1   46.081  ? 641  ILE A HB   1 c 
ATOM   9791  H  HG12 . ILE A 1 635 ? 1.126   18.433  27.595  1   42.597  ? 641  ILE A HG12 1 c 
ATOM   9792  H  HG13 . ILE A 1 635 ? 0.328   17.073  27.756  1   42.516  ? 641  ILE A HG13 1 c 
ATOM   9793  H  HG21 . ILE A 1 635 ? 1.524   18.274  24.556  1   47.083  ? 641  ILE A HG21 1 c 
ATOM   9794  H  HG22 . ILE A 1 635 ? 1.097   19.616  25.285  1   47.136  ? 641  ILE A HG22 1 c 
ATOM   9795  H  HG23 . ILE A 1 635 ? 0.19    19.013  24.133  1   47.12   ? 641  ILE A HG23 1 c 
ATOM   9796  H  HD11 . ILE A 1 635 ? 1.838   16.019  26.275  1   42.024  ? 641  ILE A HD11 1 c 
ATOM   9797  H  HD12 . ILE A 1 635 ? 2.609   16.61   27.537  1   42.086  ? 641  ILE A HD12 1 c 
ATOM   9798  H  HD13 . ILE A 1 635 ? 2.645   17.383  26.148  1   42.133  ? 641  ILE A HD13 1 c 
ATOM   9799  N  N    . LYS A 1 636 ? -2.348  20.411  24.978  1   44.61   ? 642  LYS A N    1 ? 
ATOM   9800  C  CA   . LYS A 1 636 ? -3.219  20.918  23.926  1   53.549  ? 642  LYS A CA   1 ? 
ATOM   9801  C  C    . LYS A 1 636 ? -2.519  22.044  23.129  1   60.125  ? 642  LYS A C    1 ? 
ATOM   9802  O  O    . LYS A 1 636 ? -1.62   22.72   23.711  1   52.197  ? 642  LYS A O    1 ? 
ATOM   9803  C  CB   . LYS A 1 636 ? -4.538  21.416  24.528  1   60.134  ? 642  LYS A CB   1 ? 
ATOM   9804  C  CG   . LYS A 1 636 ? -4.355  22.486  25.603  1   74.837  ? 642  LYS A CG   1 ? 
ATOM   9805  C  CD   . LYS A 1 636 ? -5.621  22.919  26.33   1   75.464  ? 642  LYS A CD   1 ? 
ATOM   9806  C  CE   . LYS A 1 636 ? -6.255  21.794  27.06   1   85.729  ? 642  LYS A CE   1 ? 
ATOM   9807  N  NZ   . LYS A 1 636 ? -7.348  22.245  27.925  1   88.246  ? 642  LYS A NZ   1 ? 
ATOM   9808  O  OXT  . LYS A 1 636 ? -2.909  22.215  21.935  1   57.273  ? 642  LYS A OXT  1 ? 
ATOM   9809  H  H    . LYS A 1 636 ? -1.908  21.012  25.508  1   46.574  ? 642  LYS A H    1 c 
ATOM   9810  H  HA   . LYS A 1 636 ? -3.423  20.177  23.302  1   53.704  ? 642  LYS A HA   1 c 
ATOM   9811  H  HB2  . LYS A 1 636 ? -5.097  21.785  23.811  1   61.63   ? 642  LYS A HB2  1 c 
ATOM   9812  H  HB3  . LYS A 1 636 ? -5.014  20.654  24.919  1   61.817  ? 642  LYS A HB3  1 c 
ATOM   9813  H  HG2  . LYS A 1 636 ? -3.716  22.15   26.267  1   70.897  ? 642  LYS A HG2  1 c 
ATOM   9814  H  HG3  . LYS A 1 636 ? -3.95   23.277  25.184  1   71.182  ? 642  LYS A HG3  1 c 
ATOM   9815  H  HD2  . LYS A 1 636 ? -5.399  23.632  26.967  1   77.66   ? 642  LYS A HD2  1 c 
ATOM   9816  H  HD3  . LYS A 1 636 ? -6.261  23.279  25.677  1   77.613  ? 642  LYS A HD3  1 c 
ATOM   9817  H  HE2  . LYS A 1 636 ? -6.602  21.148  26.421  1   83.302  ? 642  LYS A HE2  1 c 
ATOM   9818  H  HE3  . LYS A 1 636 ? -5.584  21.345  27.606  1   83.573  ? 642  LYS A HE3  1 c 
ATOM   9819  H  HZ1  . LYS A 1 636 ? -8.011  22.6    27.42   1   87.392  ? 642  LYS A HZ1  1 c 
ATOM   9820  H  HZ2  . LYS A 1 636 ? -7.044  22.875  28.501  1   87.16   ? 642  LYS A HZ2  1 c 
ATOM   9821  H  HZ3  . LYS A 1 636 ? -7.675  21.544  28.396  1   87.392  ? 642  LYS A HZ3  1 c 
HETATM 9822  ZN ZN   . ZN  B 2 .   ? 16.555  8.273   25.172  1   41.603  ? 701  ZN  A ZN   1 ? 
HETATM 9823  O  O    . HOH C 3 .   ? 21.74   2.873   -2.421  1   27.95   ? 801  HOH A O    1 ? 
HETATM 9824  O  O    . HOH C 3 .   ? -4.97   21.437  20.557  1   44.081  ? 802  HOH A O    1 ? 
HETATM 9825  O  O    . HOH C 3 .   ? 15.057  0.484   27.266  1   13.063  ? 803  HOH A O    1 ? 
HETATM 9826  O  O    . HOH C 3 .   ? 11.543  8.204   -20.017 1   55.142  ? 804  HOH A O    1 ? 
HETATM 9827  O  O    . HOH C 3 .   ? 42.498  -18.427 2.984   1   54.148  ? 805  HOH A O    1 ? 
HETATM 9828  O  O    . HOH C 3 .   ? -8.294  6.512   24.129  1   45.177  ? 806  HOH A O    1 ? 
HETATM 9829  O  O    . HOH C 3 .   ? -8.951  20.773  26.72   1   60.819  ? 807  HOH A O    1 ? 
HETATM 9830  O  O    . HOH C 3 .   ? 3.21    -6.178  24.087  1   47.134  ? 808  HOH A O    1 ? 
HETATM 9831  O  O    . HOH C 3 .   ? 36.939  -23.232 -0.348  1   51.024  ? 809  HOH A O    1 ? 
HETATM 9832  O  O    . HOH C 3 .   ? 27.894  7.903   25.637  1   47.199  ? 810  HOH A O    1 ? 
HETATM 9833  O  O    . HOH C 3 .   ? 31.898  -18.349 17.346  1   56.767  ? 811  HOH A O    1 ? 
HETATM 9834  O  O    . HOH C 3 .   ? 15.293  -11.447 -8.859  1   42.357  ? 812  HOH A O    1 ? 
HETATM 9835  O  O    . HOH C 3 .   ? 28.628  2.802   -2.457  1   34.58   ? 813  HOH A O    1 ? 
HETATM 9836  O  O    . HOH C 3 .   ? 44.782  -3.446  23.834  1   52.096  ? 814  HOH A O    1 ? 
HETATM 9837  O  O    . HOH C 3 .   ? 29.495  -19.091 13.692  1   45.896  ? 815  HOH A O    1 ? 
HETATM 9838  O  O    . HOH C 3 .   ? 50.418  -3.234  20.562  1   54.642  ? 816  HOH A O    1 ? 
HETATM 9839  O  O    . HOH C 3 .   ? 44.611  -13.599 -16.414 1   33.494  ? 817  HOH A O    1 ? 
HETATM 9840  O  O    . HOH C 3 .   ? -10.875 10.913  7.287   1   47.151  ? 818  HOH A O    1 ? 
HETATM 9841  O  O    . HOH C 3 .   ? 26.62   -26.035 2.293   1   45.23   ? 819  HOH A O    1 ? 
HETATM 9842  O  O    . HOH C 3 .   ? 17.823  25.08   21.068  1   46.09   ? 820  HOH A O    1 ? 
HETATM 9843  O  O    . HOH C 3 .   ? -6.707  12.689  24.675  1   44.121  ? 821  HOH A O    1 ? 
HETATM 9844  O  O    . HOH C 3 .   ? 44.12   7.617   -18.414 1   45.343  ? 822  HOH A O    1 ? 
HETATM 9845  O  O    . HOH C 3 .   ? 14.426  -17.951 8.37    1   35.038  ? 823  HOH A O    1 ? 
HETATM 9846  O  O    . HOH C 3 .   ? 23.787  8.8     -20.698 1   39.22   ? 824  HOH A O    1 ? 
HETATM 9847  O  O    . HOH C 3 .   ? -1.436  -1.192  30.908  1   38.734  ? 825  HOH A O    1 ? 
HETATM 9848  O  O    . HOH C 3 .   ? 33.083  13.71   -20.539 1   54.443  ? 826  HOH A O    1 ? 
HETATM 9849  O  O    . HOH C 3 .   ? 32.649  6.307   4.431   1   54.476  ? 827  HOH A O    1 ? 
HETATM 9850  O  O    . HOH C 3 .   ? 11.105  -9.756  23.422  1   55.263  ? 828  HOH A O    1 ? 
HETATM 9851  O  O    . HOH C 3 .   ? 36.263  -16.057 8.575   1   56.375  ? 829  HOH A O    1 ? 
HETATM 9852  O  O    . HOH C 3 .   ? 50.404  2.866   16.88   1   43.93   ? 830  HOH A O    1 ? 
HETATM 9853  O  O    . HOH C 3 .   ? 27.554  -0.515  2.774   1   37.018  ? 831  HOH A O    1 ? 
HETATM 9854  O  O    . HOH C 3 .   ? 23.099  2.654   2.067   1   37.727  ? 832  HOH A O    1 ? 
HETATM 9855  O  O    . HOH C 3 .   ? 21.423  19.119  12.939  1   42.273  ? 833  HOH A O    1 ? 
HETATM 9856  O  O    . HOH C 3 .   ? 22.165  5.615   -2.374  1   37.59   ? 834  HOH A O    1 ? 
HETATM 9857  O  O    . HOH C 3 .   ? 51.019  10.768  -5.882  1   61.087  ? 835  HOH A O    1 ? 
HETATM 9858  O  O    . HOH C 3 .   ? 17.404  -20.838 -12.572 1   38.428  ? 836  HOH A O    1 ? 
HETATM 9859  O  O    . HOH C 3 .   ? 5.814   -13.312 6.853   1   38.202  ? 837  HOH A O    1 ? 
HETATM 9860  O  O    . HOH C 3 .   ? 41.696  -16.791 11.777  1   56.287  ? 838  HOH A O    1 ? 
HETATM 9861  O  O    . HOH C 3 .   ? 38.802  -11.132 4.616   1   31.984  ? 839  HOH A O    1 ? 
HETATM 9862  O  O    . HOH C 3 .   ? -2.728  5.654   33.712  1   37.902  ? 840  HOH A O    1 ? 
HETATM 9863  O  O    . HOH C 3 .   ? 44.673  -7.065  20.768  1   40.083  ? 841  HOH A O    1 ? 
HETATM 9864  O  O    . HOH C 3 .   ? 37.775  2.029   19.765  1   48.496  ? 842  HOH A O    1 ? 
HETATM 9865  O  O    . HOH C 3 .   ? -2.114  -2.595  42.13   1   54.468  ? 843  HOH A O    1 ? 
HETATM 9866  O  O    . HOH C 3 .   ? 20.373  20.645  34.473  1   54.276  ? 844  HOH A O    1 ? 
HETATM 9867  O  O    . HOH C 3 .   ? 30.871  -7.02   5.052   1   34.409  ? 845  HOH A O    1 ? 
HETATM 9868  O  O    . HOH C 3 .   ? -1.766  25.312  23.644  1   51.038  ? 846  HOH A O    1 ? 
HETATM 9869  O  O    . HOH C 3 .   ? 46.135  7.858   9.137   1   36.603  ? 847  HOH A O    1 ? 
HETATM 9870  O  O    . HOH C 3 .   ? 18.445  22.533  16.106  1   36.683  ? 848  HOH A O    1 ? 
HETATM 9871  O  O    . HOH C 3 .   ? 10.318  -1.098  23.648  1   41.963  ? 849  HOH A O    1 ? 
HETATM 9872  O  O    . HOH C 3 .   ? 24.071  10.466  37.068  1   52.409  ? 850  HOH A O    1 ? 
HETATM 9873  O  O    . HOH C 3 .   ? 12.921  21.523  1.98    1   50.596  ? 851  HOH A O    1 ? 
HETATM 9874  O  O    . HOH C 3 .   ? 7.885   -14.657 -0.994  1   44.636  ? 852  HOH A O    1 ? 
HETATM 9875  O  O    . HOH C 3 .   ? 3.615   26.162  35.892  1   52.697  ? 853  HOH A O    1 ? 
HETATM 9876  O  O    . HOH C 3 .   ? 43.912  -12.031 9.439   1   45.164  ? 854  HOH A O    1 ? 
HETATM 9877  O  O    . HOH C 3 .   ? 50.877  -8.971  1.928   1   42.022  ? 855  HOH A O    1 ? 
HETATM 9878  O  O    . HOH C 3 .   ? 45.982  -13.259 2.102   1   50.262  ? 856  HOH A O    1 ? 
HETATM 9879  O  O    . HOH C 3 .   ? 50.56   4.94    12.763  1   36.86   ? 857  HOH A O    1 ? 
HETATM 9880  O  O    . HOH C 3 .   ? 2.943   28.813  32.925  1   47.476  ? 858  HOH A O    1 ? 
HETATM 9881  O  O    . HOH C 3 .   ? 26.786  -6.168  0.5     1   33.915  ? 859  HOH A O    1 ? 
HETATM 9882  O  O    . HOH C 3 .   ? 11.787  10.224  20.134  1   44.131  ? 860  HOH A O    1 ? 
HETATM 9883  O  O    . HOH C 3 .   ? 37.088  6.528   10.313  1   53.856  ? 861  HOH A O    1 ? 
HETATM 9884  O  O    . HOH C 3 .   ? 49.452  -13.933 3.568   1   55.691  ? 862  HOH A O    1 ? 
HETATM 9885  O  O    . HOH C 3 .   ? 48.515  5.385   6.746   1   40.428  ? 863  HOH A O    1 ? 
HETATM 9886  O  O    . HOH C 3 .   ? 36.154  -20.170 -13.933 1   55.212  ? 864  HOH A O    1 ? 
HETATM 9887  O  O    . HOH C 3 .   ? 40.194  -16.22  13.863  1   54.569  ? 865  HOH A O    1 ? 
HETATM 9888  O  O    . HOH C 3 .   ? 47.288  -11.392 -2.211  1   35.761  ? 866  HOH A O    1 ? 
HETATM 9889  O  O    . HOH C 3 .   ? 42.713  -10.823 7.312   1   44.837  ? 867  HOH A O    1 ? 
HETATM 9890  O  O    . HOH C 3 .   ? 10.145  21.098  40.727  1   43.043  ? 868  HOH A O    1 ? 
HETATM 9891  O  O    . HOH C 3 .   ? 52.051  6.074   -1.728  1   37.346  ? 869  HOH A O    1 ? 
HETATM 9892  O  O    . HOH C 3 .   ? 19.149  3.416   8.311   1   39.172  ? 870  HOH A O    1 ? 
HETATM 9893  O  O    . HOH C 3 .   ? 4.17    7.109   -6.321  1   39.166  ? 871  HOH A O    1 ? 
HETATM 9894  O  O    . HOH C 3 .   ? 18.784  18.955  35.206  1   47.293  ? 872  HOH A O    1 ? 
HETATM 9895  O  O    . HOH C 3 .   ? 28.528  -4.233  -2.017  1   40.201  ? 873  HOH A O    1 ? 
HETATM 9896  O  O    . HOH C 3 .   ? -1.306  23.562  20.318  1   44.048  ? 874  HOH A O    1 ? 
HETATM 9897  O  O    . HOH C 3 .   ? -0.701  5.048   -1.928  1   47.926  ? 875  HOH A O    1 ? 
HETATM 9898  O  O    . HOH C 3 .   ? 18.892  7.592   -19.89  1   65.797  ? 876  HOH A O    1 ? 
HETATM 9899  O  O    . HOH C 3 .   ? 22.966  -29.395 2.359   1   51.322  ? 877  HOH A O    1 ? 
HETATM 9900  O  O    . HOH C 3 .   ? 27.682  -7.519  -17.565 1   49.428  ? 878  HOH A O    1 ? 
HETATM 9901  O  O    . HOH C 3 .   ? 22.809  13.039  16.313  1   45.282  ? 879  HOH A O    1 ? 
HETATM 9902  O  O    . HOH C 3 .   ? 31.716  -24.389 -1.577  1   40.481  ? 880  HOH A O    1 ? 
HETATM 9903  O  O    . HOH C 3 .   ? 17.008  8.463   23.066  1   32.494  ? 881  HOH A O    1 ? 
HETATM 9904  O  O    . HOH C 3 .   ? 18.049  3.919   -13.812 1   51.45   ? 882  HOH A O    1 ? 
HETATM 9905  O  O    . HOH C 3 .   ? 48.914  -16.95  13.187  1   48.059  ? 883  HOH A O    1 ? 
HETATM 9906  O  O    . HOH C 3 .   ? 19.062  -10.779 -12.949 1   47.725  ? 884  HOH A O    1 ? 
HETATM 9907  O  O    . HOH C 3 .   ? 12.937  6.753   9.423   1   41.98   ? 885  HOH A O    1 ? 
HETATM 9908  O  O    . HOH C 3 .   ? 10.324  14.824  -3.725  1   50.929  ? 886  HOH A O    1 ? 
HETATM 9909  O  O    . HOH C 3 .   ? 6.49    -1.754  9.334   1   37.786  ? 887  HOH A O    1 ? 
HETATM 9910  O  O    . HOH C 3 .   ? 26.668  -28.854 -3.901  1   47.678  ? 888  HOH A O    1 ? 
HETATM 9911  O  O    . HOH C 3 .   ? 14.299  22.252  39.865  1   54.361  ? 889  HOH A O    1 ? 
HETATM 9912  O  O    . HOH C 3 .   ? 54.864  -2.769  -4.747  1   29.959  ? 890  HOH A O    1 ? 
HETATM 9913  O  O    . HOH C 3 .   ? 37.377  5.536   -20.1   1   41.151  ? 891  HOH A O    1 ? 
HETATM 9914  O  O    . HOH C 3 .   ? 3.797   -2.084  -5.876  1   50.163  ? 892  HOH A O    1 ? 
HETATM 9915  O  O    . HOH C 3 .   ? 15.132  6.721   24.633  1   31.4    ? 893  HOH A O    1 ? 
HETATM 9916  O  O    . HOH C 3 .   ? 41.567  -10.247 -22.649 1   46.298  ? 894  HOH A O    1 ? 
HETATM 9917  O  O    . HOH C 3 .   ? 18.565  25.119  35.73   1   50.57   ? 895  HOH A O    1 ? 
HETATM 9918  O  O    . HOH C 3 .   ? 50.813  -12.071 19.906  1   41.365  ? 896  HOH A O    1 ? 
HETATM 9919  O  O    . HOH C 3 .   ? 34.292  -15.521 -12.535 1   38.014  ? 897  HOH A O    1 ? 
HETATM 9920  O  O    . HOH C 3 .   ? 9.882   14.776  20.299  1   38.12   ? 898  HOH A O    1 ? 
HETATM 9921  O  O    . HOH C 3 .   ? 15.575  2.752   -13.457 1   43.267  ? 899  HOH A O    1 ? 
HETATM 9922  O  O    . HOH C 3 .   ? 21.862  7.463   15.629  1   44.851  ? 900  HOH A O    1 ? 
HETATM 9923  O  O    . HOH C 3 .   ? 48.145  -9.851  -22.946 1   57.038  ? 901  HOH A O    1 ? 
HETATM 9924  O  O    . HOH C 3 .   ? 16.735  -0.614  21.119  1   52.485  ? 902  HOH A O    1 ? 
HETATM 9925  O  O    . HOH C 3 .   ? 9.962   -8.814  -6.146  1   47.685  ? 903  HOH A O    1 ? 
HETATM 9926  O  O    . HOH C 3 .   ? 9.843   -6.398  23.844  1   49.809  ? 904  HOH A O    1 ? 
HETATM 9927  O  O    . HOH C 3 .   ? 11.469  -22.208 17.242  1   57.292  ? 905  HOH A O    1 ? 
HETATM 9928  O  O    . HOH C 3 .   ? 12.076  -12.558 -6.339  1   35.351  ? 906  HOH A O    1 ? 
HETATM 9929  O  O    . HOH C 3 .   ? 35.272  -24.197 11.796  1   56.346  ? 907  HOH A O    1 ? 
HETATM 9930  O  O    . HOH C 3 .   ? 47.849  -11.811 3.466   1   51.335  ? 908  HOH A O    1 ? 
HETATM 9931  O  O    . HOH C 3 .   ? 6.147   25.988  13.031  1   51.175  ? 909  HOH A O    1 ? 
HETATM 9932  O  O    . HOH C 3 .   ? 26.31   7.973   23.348  1   44.004  ? 910  HOH A O    1 ? 
HETATM 9933  O  O    . HOH C 3 .   ? 20.831  8.851   -9.958  1   48.032  ? 911  HOH A O    1 ? 
HETATM 9934  O  O    . HOH C 3 .   ? 24.937  11.461  15.795  1   50.985  ? 912  HOH A O    1 ? 
HETATM 9935  O  O    . HOH C 3 .   ? 39.483  9.106   4.027   1   52.927  ? 913  HOH A O    1 ? 
HETATM 9936  O  O    . HOH C 3 .   ? 16.281  25.071  23.334  1   40.924  ? 914  HOH A O    1 ? 
HETATM 9937  O  O    . HOH C 3 .   ? 44.364  3.253   -18.579 1   41.911  ? 915  HOH A O    1 ? 
HETATM 9938  O  O    . HOH C 3 .   ? 15.781  11.65   26.688  1   36.299  ? 916  HOH A O    1 ? 
HETATM 9939  O  O    . HOH C 3 .   ? -0      8.174   0       0.5 37.653  ? 917  HOH A O    1 ? 
HETATM 9940  O  O    . HOH C 3 .   ? 50.4    -10.326 -1.415  1   40.102  ? 918  HOH A O    1 ? 
HETATM 9941  O  O    . HOH C 3 .   ? 21.082  11.948  37.453  1   54.028  ? 919  HOH A O    1 ? 
HETATM 9942  O  O    . HOH C 3 .   ? 6.624   11.354  -12.761 1   45.625  ? 920  HOH A O    1 ? 
HETATM 9943  O  O    . HOH C 3 .   ? 2.748   13.261  1.859   1   38.023  ? 921  HOH A O    1 ? 
HETATM 9944  O  O    . HOH C 3 .   ? 39.454  8.434   -1.972  1   35.126  ? 922  HOH A O    1 ? 
HETATM 9945  O  O    . HOH C 3 .   ? 45.616  1.176   -19.576 1   45.362  ? 923  HOH A O    1 ? 
HETATM 9946  O  O    . HOH C 3 .   ? 23.364  -1.609  28.956  1   44.645  ? 924  HOH A O    1 ? 
HETATM 9947  O  O    . HOH C 3 .   ? 53.945  -19.96  11.827  1   49.438  ? 925  HOH A O    1 ? 
HETATM 9948  O  O    . HOH C 3 .   ? 51.532  -1.58   -5.639  1   31.345  ? 926  HOH A O    1 ? 
HETATM 9949  O  O    . HOH C 3 .   ? 1.745   -11.342 8.719   1   49.615  ? 927  HOH A O    1 ? 
HETATM 9950  O  O    . HOH C 3 .   ? 45.209  -9.616  -15.922 1   39.452  ? 928  HOH A O    1 ? 
HETATM 9951  O  O    . HOH C 3 .   ? 8.725   -17.803 -0.121  1   41.252  ? 929  HOH A O    1 ? 
HETATM 9952  O  O    . HOH C 3 .   ? 33.043  -25.402 -14.160 1   40.531  ? 930  HOH A O    1 ? 
HETATM 9953  O  O    . HOH C 3 .   ? 12.45   21.694  12.937  1   48.466  ? 931  HOH A O    1 ? 
HETATM 9954  O  O    . HOH C 3 .   ? 25.424  -10.83  13.695  1   41.844  ? 932  HOH A O    1 ? 
HETATM 9955  O  O    . HOH C 3 .   ? 12.457  13.374  43.18   1   45.415  ? 933  HOH A O    1 ? 
HETATM 9956  O  O    . HOH C 3 .   ? 22.459  13.446  18.735  1   34.405  ? 934  HOH A O    1 ? 
HETATM 9957  O  O    . HOH C 3 .   ? 9.45    28.083  12.504  1   44.09   ? 935  HOH A O    1 ? 
HETATM 9958  O  O    . HOH C 3 .   ? 16.894  2.837   39.992  1   54.013  ? 936  HOH A O    1 ? 
HETATM 9959  O  O    . HOH C 3 .   ? 7.672   -5.632  28.116  1   57.863  ? 937  HOH A O    1 ? 
HETATM 9960  O  O    . HOH C 3 .   ? 30.951  -6.864  -18.82  1   47.329  ? 938  HOH A O    1 ? 
HETATM 9961  O  O    . HOH C 3 .   ? 33.852  11.278  -21.779 1   47      ? 939  HOH A O    1 ? 
HETATM 9962  O  O    . HOH C 3 .   ? 20.458  -0.069  -21.095 1   52.39   ? 940  HOH A O    1 ? 
HETATM 9963  O  O    . HOH C 3 .   ? 31.346  -3.108  -1.995  1   26.445  ? 941  HOH A O    1 ? 
HETATM 9964  O  O    . HOH C 3 .   ? 2.702   7.348   1.986   1   55.872  ? 942  HOH A O    1 ? 
HETATM 9965  O  O    . HOH C 3 .   ? 20.209  -7.712  31.69   1   45.57   ? 943  HOH A O    1 ? 
HETATM 9966  O  O    . HOH C 3 .   ? 12.759  28.455  28.361  1   51.348  ? 944  HOH A O    1 ? 
HETATM 9967  O  O    . HOH C 3 .   ? 30.613  -29.442 -10.182 1   42.449  ? 945  HOH A O    1 ? 
HETATM 9968  O  O    . HOH C 3 .   ? -0.299  -4.398  15.263  1   42.309  ? 946  HOH A O    1 ? 
HETATM 9969  O  O    . HOH C 3 .   ? 18.419  -5.713  -15.666 1   42.428  ? 947  HOH A O    1 ? 
HETATM 9970  O  O    . HOH C 3 .   ? 10.661  -14.334 -7.389  1   50.165  ? 948  HOH A O    1 ? 
HETATM 9971  O  O    . HOH C 3 .   ? 13.312  13.043  17.378  1   45.484  ? 949  HOH A O    1 ? 
HETATM 9972  O  O    . HOH C 3 .   ? 48.624  -13.761 20.684  1   44.318  ? 950  HOH A O    1 ? 
HETATM 9973  O  O    . HOH C 3 .   ? 38.546  -17.541 8.811   1   35.82   ? 951  HOH A O    1 ? 
HETATM 9974  O  O    . HOH C 3 .   ? 19.802  13.004  19.156  1   38.067  ? 952  HOH A O    1 ? 
HETATM 9975  O  O    . HOH C 3 .   ? 13.616  4.904   17.671  1   33.502  ? 953  HOH A O    1 ? 
HETATM 9976  O  O    . HOH C 3 .   ? 43.561  -3.139  -21.817 1   43.605  ? 954  HOH A O    1 ? 
HETATM 9977  O  O    . HOH C 3 .   ? 24.067  4.507   -0.878  1   41.948  ? 955  HOH A O    1 ? 
HETATM 9978  O  O    . HOH C 3 .   ? -1.844  0.613   37.894  1   49.662  ? 956  HOH A O    1 ? 
HETATM 9979  O  O    . HOH C 3 .   ? 19.006  -6.201  13.707  1   46.323  ? 957  HOH A O    1 ? 
HETATM 9980  O  O    . HOH C 3 .   ? 25.063  3.246   23.287  1   43.721  ? 958  HOH A O    1 ? 
HETATM 9981  O  O    . HOH C 3 .   ? 17.713  -3.312  44.028  1   62.135  ? 959  HOH A O    1 ? 
HETATM 9982  O  O    . HOH C 3 .   ? 12.82   -23.565 -14.878 1   61.109  ? 960  HOH A O    1 ? 
HETATM 9983  O  O    . HOH C 3 .   ? 33.621  6.054   -4.34   1   35.893  ? 961  HOH A O    1 ? 
HETATM 9984  O  O    . HOH C 3 .   ? 42.529  11.47   -19.208 1   54.174  ? 962  HOH A O    1 ? 
HETATM 9985  O  O    . HOH C 3 .   ? 13.091  -3.102  10.382  1   39.145  ? 963  HOH A O    1 ? 
HETATM 9986  O  O    . HOH C 3 .   ? 1.552   -1.507  -1.498  1   34.313  ? 964  HOH A O    1 ? 
HETATM 9987  O  O    . HOH C 3 .   ? 24.641  -5.718  -22.198 1   50.656  ? 965  HOH A O    1 ? 
HETATM 9988  O  O    . HOH C 3 .   ? 44.115  5.155   -15.024 1   37.443  ? 966  HOH A O    1 ? 
HETATM 9989  O  O    . HOH C 3 .   ? 27.606  10.379  -24.606 1   57.597  ? 967  HOH A O    1 ? 
HETATM 9990  O  O    . HOH C 3 .   ? 25.605  2.456   35.317  1   47.239  ? 968  HOH A O    1 ? 
HETATM 9991  O  O    . HOH C 3 .   ? 17.733  10.198  25.629  1   33.256  ? 969  HOH A O    1 ? 
HETATM 9992  O  O    . HOH C 3 .   ? 49.251  -12.417 -3.764  1   38.472  ? 970  HOH A O    1 ? 
HETATM 9993  O  O    . HOH C 3 .   ? -0.624  0.605   11.058  1   43.823  ? 971  HOH A O    1 ? 
HETATM 9994  O  O    . HOH C 3 .   ? 43.465  -17.243 -10.205 1   40.366  ? 972  HOH A O    1 ? 
HETATM 9995  O  O    . HOH C 3 .   ? 6.530   13.620  -6.581  1   43.618  ? 973  HOH A O    1 ? 
HETATM 9996  O  O    . HOH C 3 .   ? -5.006  14.295  38.033  1   49.53   ? 974  HOH A O    1 ? 
HETATM 9997  O  O    . HOH C 3 .   ? 51.67   -10.375 9.328   1   28.227  ? 975  HOH A O    1 ? 
HETATM 9998  O  O    . HOH C 3 .   ? 17.055  13.542  38.283  1   45.876  ? 976  HOH A O    1 ? 
HETATM 9999  O  O    . HOH C 3 .   ? 8.508   30.878  33.239  1   50.924  ? 977  HOH A O    1 ? 
HETATM 10000 O  O    . HOH C 3 .   ? 4.411   25.362  40.33   1   55.706  ? 978  HOH A O    1 ? 
HETATM 10001 O  O    . HOH C 3 .   ? 12.061  28.573  18.854  1   46.214  ? 979  HOH A O    1 ? 
HETATM 10002 O  O    . HOH C 3 .   ? 18.509  9.518   40.24   1   44.467  ? 980  HOH A O    1 ? 
HETATM 10003 O  O    . HOH C 3 .   ? 42.308  -22.822 -2.208  1   50.565  ? 981  HOH A O    1 ? 
HETATM 10004 O  O    . HOH C 3 .   ? 11.825  -6.955  12.589  1   52.688  ? 982  HOH A O    1 ? 
HETATM 10005 O  O    . HOH C 3 .   ? 15.217  -4.265  42.3    1   59.454  ? 983  HOH A O    1 ? 
HETATM 10006 O  O    . HOH C 3 .   ? 1.972   13.48   -1.4    1   47.589  ? 984  HOH A O    1 ? 
HETATM 10007 O  O    . HOH C 3 .   ? 4.44    15.906  13.721  1   34.558  ? 985  HOH A O    1 ? 
HETATM 10008 O  O    . HOH C 3 .   ? -5.764  19.929  39.999  1   57.614  ? 986  HOH A O    1 ? 
HETATM 10009 O  O    . HOH C 3 .   ? 35.472  -21.536 -10.686 1   37.197  ? 987  HOH A O    1 ? 
HETATM 10010 O  O    . HOH C 3 .   ? 25.579  12.737  33.142  1   45.097  ? 988  HOH A O    1 ? 
HETATM 10011 O  O    . HOH C 3 .   ? 27.311  -13.543 18.718  1   54.498  ? 989  HOH A O    1 ? 
HETATM 10012 O  O    . HOH C 3 .   ? 10.755  -18.704 -3.455  1   42.222  ? 990  HOH A O    1 ? 
HETATM 10013 O  O    . HOH C 3 .   ? 42.493  -18.223 8.822   1   48.343  ? 991  HOH A O    1 ? 
HETATM 10014 O  O    . HOH C 3 .   ? 17.648  5.259   34.865  1   39.754  ? 992  HOH A O    1 ? 
HETATM 10015 O  O    . HOH C 3 .   ? 13.279  12.844  -8.035  1   52.963  ? 993  HOH A O    1 ? 
HETATM 10016 O  O    . HOH C 3 .   ? 22.529  -21.68  -15.464 1   49.785  ? 994  HOH A O    1 ? 
HETATM 10017 O  O    . HOH C 3 .   ? 29.749  -1.383  -28.161 1   49.933  ? 995  HOH A O    1 ? 
HETATM 10018 O  O    . HOH C 3 .   ? 9.076   15.466  -1.156  1   49.976  ? 996  HOH A O    1 ? 
HETATM 10019 O  O    . HOH C 3 .   ? 35.416  10.927  23.017  1   54.498  ? 997  HOH A O    1 ? 
HETATM 10020 O  O    . HOH C 3 .   ? 22.206  -9.004  -8.445  1   41.133  ? 998  HOH A O    1 ? 
HETATM 10021 O  O    . HOH C 3 .   ? 30.102  16.596  -10.749 1   55.597  ? 999  HOH A O    1 ? 
HETATM 10022 O  O    . HOH C 3 .   ? 35.536  -29.074 -6.153  1   44.713  ? 1000 HOH A O    1 ? 
HETATM 10023 O  O    . HOH C 3 .   ? 49.858  -0.615  -7.503  1   29.504  ? 1001 HOH A O    1 ? 
HETATM 10024 O  O    . HOH C 3 .   ? 52.283  -1.592  -1.36   1   35.922  ? 1002 HOH A O    1 ? 
HETATM 10025 O  O    . HOH C 3 .   ? 36.976  -15.477 -15.568 1   52.946  ? 1003 HOH A O    1 ? 
HETATM 10026 O  O    . HOH C 3 .   ? 19.241  13.693  8.763   1   65.543  ? 1004 HOH A O    1 ? 
HETATM 10027 O  O    . HOH C 3 .   ? 34.477  -12.373 -19.849 1   60.05   ? 1005 HOH A O    1 ? 
HETATM 10028 O  O    . HOH C 3 .   ? 46.868  -4.744  5.432   1   32.854  ? 1006 HOH A O    1 ? 
HETATM 10029 O  O    . HOH C 3 .   ? 19.192  -22.436 -13.693 1   56.237  ? 1007 HOH A O    1 ? 
HETATM 10030 O  O    . HOH C 3 .   ? 33.394  -29.672 -7.005  1   49.094  ? 1008 HOH A O    1 ? 
HETATM 10031 O  O    . HOH C 3 .   ? 0.188   -0.78   -7.41   1   36.388  ? 1009 HOH A O    1 ? 
HETATM 10032 O  O    . HOH C 3 .   ? 15.368  -24.491 -5.077  1   54.676  ? 1010 HOH A O    1 ? 
HETATM 10033 O  O    . HOH C 3 .   ? 45.246  -19.777 -0.382  1   52.182  ? 1011 HOH A O    1 ? 
HETATM 10034 O  O    . HOH C 3 .   ? 44.093  9.343   3.56    1   50.882  ? 1012 HOH A O    1 ? 
HETATM 10035 O  O    . HOH C 3 .   ? 12.392  29.282  31.336  1   54.972  ? 1013 HOH A O    1 ? 
HETATM 10036 O  O    . HOH C 3 .   ? 25.465  12.875  -18.459 1   48.891  ? 1014 HOH A O    1 ? 
HETATM 10037 O  O    . HOH C 3 .   ? 15.009  32.665  24.119  1   52.029  ? 1015 HOH A O    1 ? 
HETATM 10038 O  O    . HOH C 3 .   ? 26.616  13.439  25.958  1   54.722  ? 1016 HOH A O    1 ? 
HETATM 10039 O  O    . HOH C 3 .   ? 4.222   14.167  11.421  1   41.423  ? 1017 HOH A O    1 ? 
HETATM 10040 O  O    . HOH C 3 .   ? -0.16   -0.807  12.905  1   37.844  ? 1018 HOH A O    1 ? 
HETATM 10041 O  O    . HOH C 3 .   ? 1.829   0.422   0.436   1   37.727  ? 1019 HOH A O    1 ? 
HETATM 10042 O  O    . HOH C 3 .   ? 8.939   -2.854  41.145  1   48.115  ? 1020 HOH A O    1 ? 
HETATM 10043 O  O    . HOH C 3 .   ? 49.191  -0.919  2.81    1   34.449  ? 1021 HOH A O    1 ? 
HETATM 10044 O  O    . HOH C 3 .   ? 38.893  -12.646 20.084  1   58.366  ? 1022 HOH A O    1 ? 
HETATM 10045 O  O    . HOH C 3 .   ? 13.665  -9.037  -8.099  1   48.651  ? 1023 HOH A O    1 ? 
HETATM 10046 O  O    . HOH C 3 .   ? 23.158  -11.529 -7.607  1   34.366  ? 1024 HOH A O    1 ? 
HETATM 10047 O  O    . HOH C 3 .   ? -1.351  20.707  10.376  1   53.673  ? 1025 HOH A O    1 ? 
HETATM 10048 O  O    . HOH C 3 .   ? -2.548  -4.761  23.487  1   49.187  ? 1026 HOH A O    1 ? 
HETATM 10049 O  O    . HOH C 3 .   ? 32.51   -6.522  -21.977 1   45.891  ? 1027 HOH A O    1 ? 
HETATM 10050 O  O    . HOH C 3 .   ? 9.662   -21.064 -2.624  1   50.302  ? 1028 HOH A O    1 ? 
HETATM 10051 O  O    . HOH C 3 .   ? 19.65   10.035  -3.835  1   46.788  ? 1029 HOH A O    1 ? 
HETATM 10052 O  O    . HOH C 3 .   ? 26.75   17.534  -14.824 1   60.186  ? 1030 HOH A O    1 ? 
HETATM 10053 O  O    . HOH C 3 .   ? 35.006  -1.286  -1.031  1   34.931  ? 1031 HOH A O    1 ? 
HETATM 10054 O  O    . HOH C 3 .   ? 41.427  -9.878  4.318   1   34.966  ? 1032 HOH A O    1 ? 
HETATM 10055 O  O    . HOH C 3 .   ? 30.965  9.282   19.189  1   48.108  ? 1033 HOH A O    1 ? 
HETATM 10056 O  O    . HOH C 3 .   ? 27.357  -0.513  -27.712 1   51.038  ? 1034 HOH A O    1 ? 
HETATM 10057 O  O    . HOH C 3 .   ? 53.49   -9.246  21.895  1   51.942  ? 1035 HOH A O    1 ? 
HETATM 10058 O  O    . HOH C 3 .   ? 12.237  26.91   37.845  1   43.969  ? 1036 HOH A O    1 ? 
HETATM 10059 O  O    . HOH C 3 .   ? -2.72   29.014  28.734  1   58.821  ? 1037 HOH A O    1 ? 
HETATM 10060 O  O    . HOH C 3 .   ? 14.044  -3.634  -6.66   1   45.24   ? 1038 HOH A O    1 ? 
HETATM 10061 O  O    . HOH C 3 .   ? 43.328  -20.145 1.439   1   44.322  ? 1039 HOH A O    1 ? 
HETATM 10062 O  O    . HOH C 3 .   ? 12.516  11.305  26.743  1   41.433  ? 1040 HOH A O    1 ? 
HETATM 10063 O  O    . HOH C 3 .   ? 22.779  -32.627 -6.135  1   51.933  ? 1041 HOH A O    1 ? 
HETATM 10064 O  O    . HOH C 3 .   ? 37.737  -22.034 -9.303  1   43.78   ? 1042 HOH A O    1 ? 
HETATM 10065 O  O    . HOH C 3 .   ? 28.21   9.368   -2.37   1   47.868  ? 1043 HOH A O    1 ? 
HETATM 10066 O  O    . HOH C 3 .   ? 32.685  -1.951  15.033  1   47.248  ? 1044 HOH A O    1 ? 
HETATM 10067 O  O    . HOH C 3 .   ? 9.346   -1.743  43.334  1   46.618  ? 1045 HOH A O    1 ? 
HETATM 10068 O  O    . HOH C 3 .   ? 36.435  -16.822 -11.857 1   37.055  ? 1046 HOH A O    1 ? 
HETATM 10069 O  O    . HOH C 3 .   ? 25.012  -20.124 -19.229 1   59.791  ? 1047 HOH A O    1 ? 
HETATM 10070 O  O    . HOH C 3 .   ? 23.592  22.179  32.576  1   57.296  ? 1048 HOH A O    1 ? 
HETATM 10071 O  O    . HOH C 3 .   ? 40.651  -16.175 18.743  1   66.316  ? 1049 HOH A O    1 ? 
HETATM 10072 O  O    . HOH C 3 .   ? 11.367  26.127  11.92   1   53.833  ? 1050 HOH A O    1 ? 
HETATM 10073 O  O    . HOH C 3 .   ? 47.979  -8.029  -25.438 1   54.022  ? 1051 HOH A O    1 ? 
HETATM 10074 O  O    . HOH C 3 .   ? 1.807   30.976  30.424  1   56.843  ? 1052 HOH A O    1 ? 
HETATM 10075 O  O    . HOH C 3 .   ? 10.751  20.724  11.639  1   53.65   ? 1053 HOH A O    1 ? 
HETATM 10076 O  O    . HOH C 3 .   ? 16.405  -23.881 -14.947 1   49.228  ? 1054 HOH A O    1 ? 
HETATM 10077 O  O    . HOH C 3 .   ? 2.481   18.857  9.797   1   54.235  ? 1055 HOH A O    1 ? 
HETATM 10078 O  O    . HOH C 3 .   ? 19.584  26.64   21.737  1   54.553  ? 1056 HOH A O    1 ? 
HETATM 10079 O  O    . HOH C 3 .   ? 42.417  5.436   -22.723 1   65.387  ? 1057 HOH A O    1 ? 
HETATM 10080 O  O    . HOH C 3 .   ? 23.518  5.515   16.964  1   51.459  ? 1058 HOH A O    1 ? 
HETATM 10081 O  O    . HOH C 3 .   ? 20.161  -29.535 2.049   1   51.927  ? 1059 HOH A O    1 ? 
HETATM 10082 O  O    . HOH C 3 .   ? -7.672  4.588   36.039  1   72.319  ? 1060 HOH A O    1 ? 
HETATM 10083 O  O    . HOH C 3 .   ? 18.985  3.936   5.003   1   51.536  ? 1061 HOH A O    1 ? 
HETATM 10084 O  O    . HOH C 3 .   ? 20.137  1.988   36.331  1   55.184  ? 1062 HOH A O    1 ? 
HETATM 10085 O  O    . HOH C 3 .   ? 12.436  -30.965 -6.954  1   51.594  ? 1063 HOH A O    1 ? 
HETATM 10086 O  O    . HOH C 3 .   ? 3.261   -15.185 1.663   1   61.615  ? 1064 HOH A O    1 ? 
HETATM 10087 O  O    . HOH C 3 .   ? 4.95    -13.097 16.646  1   62.793  ? 1065 HOH A O    1 ? 
HETATM 10088 O  O    . HOH C 3 .   ? 40.565  -14.503 26.199  1   62.974  ? 1066 HOH A O    1 ? 
HETATM 10089 O  O    . HOH C 3 .   ? 9.385   10.240  -20.069 1   55.99   ? 1067 HOH A O    1 ? 
HETATM 10090 O  O    . HOH C 3 .   ? 28.29   -4.901  16.279  1   57.435  ? 1068 HOH A O    1 ? 
HETATM 10091 O  O    . HOH C 3 .   ? -4.757  10.943  43.7    1   60.021  ? 1069 HOH A O    1 ? 
HETATM 10092 O  O    . HOH C 3 .   ? 16.14   -3.917  10.927  1   51.758  ? 1070 HOH A O    1 ? 
HETATM 10093 O  O    . HOH C 3 .   ? 33.962  13.396  -7.091  1   63.123  ? 1071 HOH A O    1 ? 
HETATM 10094 O  O    . HOH C 3 .   ? 31.937  17.602  21.36   1   58.388  ? 1072 HOH A O    1 ? 
HETATM 10095 O  O    . HOH C 3 .   ? 23.544  -5.444  18.124  1   54.022  ? 1073 HOH A O    1 ? 
HETATM 10096 O  O    . HOH C 3 .   ? 17.448  7.257   9.554   1   53.431  ? 1074 HOH A O    1 ? 
HETATM 10097 O  O    . HOH C 3 .   ? -4.651  8.483   29.35   1   43.686  ? 1075 HOH A O    1 ? 
HETATM 10098 O  O    . HOH C 3 .   ? -8.818  -0.964  19.214  1   46.662  ? 1076 HOH A O    1 ? 
HETATM 10099 O  O    . HOH C 3 .   ? 44.319  -18.791 -8.146  1   49.932  ? 1077 HOH A O    1 ? 
HETATM 10100 O  O    . HOH C 3 .   ? 51.557  4.633   20.368  1   49.884  ? 1078 HOH A O    1 ? 
HETATM 10101 O  O    . HOH C 3 .   ? -8.805  14.83   5.98    1   45.563  ? 1079 HOH A O    1 ? 
HETATM 10102 O  O    . HOH C 3 .   ? -2.488  -0.198  14.585  1   51.065  ? 1080 HOH A O    1 ? 
HETATM 10103 O  O    . HOH C 3 .   ? 43.169  9.698   5.781   1   60.938  ? 1081 HOH A O    1 ? 
HETATM 10104 O  O    . HOH C 3 .   ? 21.613  2.718   4.538   1   46.075  ? 1082 HOH A O    1 ? 
HETATM 10105 O  O    . HOH C 3 .   ? 25.978  17.536  26.718  1   57.09   ? 1083 HOH A O    1 ? 
HETATM 10106 O  O    . HOH C 3 .   ? -10.875 -3.248  14.914  1   60.763  ? 1084 HOH A O    1 ? 
HETATM 10107 O  O    . HOH C 3 .   ? 39.947  -20.554 -9.171  1   45.631  ? 1085 HOH A O    1 ? 
HETATM 10108 O  O    . HOH C 3 .   ? 15.453  -32.737 -3.797  1   58.395  ? 1086 HOH A O    1 ? 
HETATM 10109 O  O    . HOH C 3 .   ? 17.389  -8.103  -11.91  1   59.296  ? 1087 HOH A O    1 ? 
HETATM 10110 O  O    . HOH C 3 .   ? 13.717  -32.647 -6.023  1   55.779  ? 1088 HOH A O    1 ? 
HETATM 10111 O  O    . HOH C 3 .   ? 35.836  5.521   8.435   1   60.908  ? 1089 HOH A O    1 ? 
HETATM 10112 O  O    . HOH C 3 .   ? 20.41   11.49   40.023  1   52.855  ? 1090 HOH A O    1 ? 
HETATM 10113 O  O    . HOH C 3 .   ? 41.481  10.693  4.364   1   47.131  ? 1091 HOH A O    1 ? 
HETATM 10114 O  O    . HOH C 3 .   ? 33.067  3.567   17.075  1   64.25   ? 1092 HOH A O    1 ? 
HETATM 10115 O  O    . HOH C 3 .   ? -0      2.721   0       0.5 50.555  ? 1093 HOH A O    1 ? 
HETATM 10116 O  O    . HOH C 3 .   ? 30.87   11.428  17.667  1   53.815  ? 1094 HOH A O    1 ? 
HETATM 10117 O  O    . HOH C 3 .   ? 10.15   -7.908  45.724  1   59.427  ? 1095 HOH A O    1 ? 
HETATM 10118 O  O    . HOH C 3 .   ? 8.839   -7.529  -8.043  1   52.986  ? 1096 HOH A O    1 ? 
HETATM 10119 O  O    . HOH C 3 .   ? 11.535  -10.271 -7.204  1   45.694  ? 1097 HOH A O    1 ? 
HETATM 10120 O  O    . HOH C 3 .   ? 40.004  -19.593 7.649   1   38.86   ? 1098 HOH A O    1 ? 
HETATM 10121 O  O    . HOH C 3 .   ? 47.484  -19.052 17.453  1   55.783  ? 1099 HOH A O    1 ? 
HETATM 10122 O  O    . HOH C 3 .   ? 52.629  3.561   22.636  1   60.799  ? 1100 HOH A O    1 ? 
HETATM 10123 O  O    . HOH C 3 .   ? 47.434  7.789   6.577   1   40.822  ? 1101 HOH A O    1 ? 
HETATM 10124 O  O    . HOH C 3 .   ? 15.474  24.387  39.65   1   55.349  ? 1102 HOH A O    1 ? 
HETATM 10125 O  O    . HOH C 3 .   ? 41.888  -19.468 10.858  1   53.697  ? 1103 HOH A O    1 ? 
HETATM 10126 O  O    . HOH C 3 .   ? 0.731   -3.119  -8.576  1   46.84   ? 1104 HOH A O    1 ? 
HETATM 10127 O  O    . HOH C 3 .   ? 42.964  -4.72   21.848  1   54.999  ? 1105 HOH A O    1 ? 
HETATM 10128 O  O    . HOH C 3 .   ? 1.137   -4.856  9.529   1   46.014  ? 1106 HOH A O    1 ? 
HETATM 10129 O  O    . HOH C 3 .   ? 26.742  3.54    -0.578  1   38.272  ? 1107 HOH A O    1 ? 
HETATM 10130 O  O    . HOH C 3 .   ? -2.637  -3.182  15.527  1   49.938  ? 1108 HOH A O    1 ? 
HETATM 10131 O  O    . HOH C 3 .   ? -8.761  3.258   34.364  1   64.566  ? 1109 HOH A O    1 ? 
HETATM 10132 O  O    . HOH C 3 .   ? 40.206  10.87   -2.392  1   45.28   ? 1110 HOH A O    1 ? 
HETATM 10133 O  O    . HOH C 3 .   ? -1.367  -7.086  15.848  1   52.129  ? 1111 HOH A O    1 ? 
HETATM 10134 O  O    . HOH C 3 .   ? 7.661   -9.364  -10.258 1   59.426  ? 1112 HOH A O    1 ? 
# 
