data_8R31
# 
_entry.id   8R31 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R31         pdb_00008r31 10.2210/pdb8r31/pdb 
WWPDB D_1292134491 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R31 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              jim.spencer@bristol.ac.uk 
_pdbx_contact_author.name_first         James 
_pdbx_contact_author.name_last          Spencer 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8611-4743 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Tooke, C.L.'    1 ? 
'Hinchliffe, P.' 2 ? 
'Spencer, J.'    3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of CTX-M-15 complexed with benzoxaborole AK-412' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Tooke, C.L.'    1 ? 
primary 'Hinchliffe, P.' 2 ? 
primary 'Spencer, J.'    3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Beta-lactamase                                                                             28292.990 1   3.5.2.6 
? ? ? 
2 non-polymer syn '4-chloranyl-N-[[(3S)-1-oxidanyl-3H-2,1$l^{4}-benzoxaborol-3-yl]methyl]benzenesulfonamide' 337.586   1   ?       
? ? ? 
3 non-polymer syn 'SULFATE ION'                                                                              96.063    3   ?       
? ? ? 
4 non-polymer syn 'CHLORIDE ION'                                                                             35.453    1   ?       
? ? ? 
5 non-polymer syn 'SODIUM ION'                                                                               22.990    3   ?       
? ? ? 
6 water       nat water                                                                                      18.015    219 ?       
? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GPQTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLV
NYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSP
RAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYF
TQPQPKAESRRDVLASAAKIVTDGL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GPQTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLV
NYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSP
RAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYF
TQPQPKAESRRDVLASAAKIVTDGL
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '4-chloranyl-N-[[(3S)-1-oxidanyl-3H-2,1$l^{4}-benzoxaborol-3-yl]methyl]benzenesulfonamide' XQN 
3 'SULFATE ION'                                                                              SO4 
4 'CHLORIDE ION'                                                                             CL  
5 'SODIUM ION'                                                                               NA  
6 water                                                                                      HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLN n 
1 4   THR n 
1 5   ALA n 
1 6   ASP n 
1 7   VAL n 
1 8   GLN n 
1 9   GLN n 
1 10  LYS n 
1 11  LEU n 
1 12  ALA n 
1 13  GLU n 
1 14  LEU n 
1 15  GLU n 
1 16  ARG n 
1 17  GLN n 
1 18  SER n 
1 19  GLY n 
1 20  GLY n 
1 21  ARG n 
1 22  LEU n 
1 23  GLY n 
1 24  VAL n 
1 25  ALA n 
1 26  LEU n 
1 27  ILE n 
1 28  ASN n 
1 29  THR n 
1 30  ALA n 
1 31  ASP n 
1 32  ASN n 
1 33  SER n 
1 34  GLN n 
1 35  ILE n 
1 36  LEU n 
1 37  TYR n 
1 38  ARG n 
1 39  ALA n 
1 40  ASP n 
1 41  GLU n 
1 42  ARG n 
1 43  PHE n 
1 44  ALA n 
1 45  MET n 
1 46  CYS n 
1 47  SER n 
1 48  THR n 
1 49  SER n 
1 50  LYS n 
1 51  VAL n 
1 52  MET n 
1 53  ALA n 
1 54  ALA n 
1 55  ALA n 
1 56  ALA n 
1 57  VAL n 
1 58  LEU n 
1 59  LYS n 
1 60  LYS n 
1 61  SER n 
1 62  GLU n 
1 63  SER n 
1 64  GLU n 
1 65  PRO n 
1 66  ASN n 
1 67  LEU n 
1 68  LEU n 
1 69  ASN n 
1 70  GLN n 
1 71  ARG n 
1 72  VAL n 
1 73  GLU n 
1 74  ILE n 
1 75  LYS n 
1 76  LYS n 
1 77  SER n 
1 78  ASP n 
1 79  LEU n 
1 80  VAL n 
1 81  ASN n 
1 82  TYR n 
1 83  ASN n 
1 84  PRO n 
1 85  ILE n 
1 86  ALA n 
1 87  GLU n 
1 88  LYS n 
1 89  HIS n 
1 90  VAL n 
1 91  ASN n 
1 92  GLY n 
1 93  THR n 
1 94  MET n 
1 95  SER n 
1 96  LEU n 
1 97  ALA n 
1 98  GLU n 
1 99  LEU n 
1 100 SER n 
1 101 ALA n 
1 102 ALA n 
1 103 ALA n 
1 104 LEU n 
1 105 GLN n 
1 106 TYR n 
1 107 SER n 
1 108 ASP n 
1 109 ASN n 
1 110 VAL n 
1 111 ALA n 
1 112 MET n 
1 113 ASN n 
1 114 LYS n 
1 115 LEU n 
1 116 ILE n 
1 117 ALA n 
1 118 HIS n 
1 119 VAL n 
1 120 GLY n 
1 121 GLY n 
1 122 PRO n 
1 123 ALA n 
1 124 SER n 
1 125 VAL n 
1 126 THR n 
1 127 ALA n 
1 128 PHE n 
1 129 ALA n 
1 130 ARG n 
1 131 GLN n 
1 132 LEU n 
1 133 GLY n 
1 134 ASP n 
1 135 GLU n 
1 136 THR n 
1 137 PHE n 
1 138 ARG n 
1 139 LEU n 
1 140 ASP n 
1 141 ARG n 
1 142 THR n 
1 143 GLU n 
1 144 PRO n 
1 145 THR n 
1 146 LEU n 
1 147 ASN n 
1 148 THR n 
1 149 ALA n 
1 150 ILE n 
1 151 PRO n 
1 152 GLY n 
1 153 ASP n 
1 154 PRO n 
1 155 ARG n 
1 156 ASP n 
1 157 THR n 
1 158 THR n 
1 159 SER n 
1 160 PRO n 
1 161 ARG n 
1 162 ALA n 
1 163 MET n 
1 164 ALA n 
1 165 GLN n 
1 166 THR n 
1 167 LEU n 
1 168 ARG n 
1 169 ASN n 
1 170 LEU n 
1 171 THR n 
1 172 LEU n 
1 173 GLY n 
1 174 LYS n 
1 175 ALA n 
1 176 LEU n 
1 177 GLY n 
1 178 ASP n 
1 179 SER n 
1 180 GLN n 
1 181 ARG n 
1 182 ALA n 
1 183 GLN n 
1 184 LEU n 
1 185 VAL n 
1 186 THR n 
1 187 TRP n 
1 188 MET n 
1 189 LYS n 
1 190 GLY n 
1 191 ASN n 
1 192 THR n 
1 193 THR n 
1 194 GLY n 
1 195 ALA n 
1 196 ALA n 
1 197 SER n 
1 198 ILE n 
1 199 GLN n 
1 200 ALA n 
1 201 GLY n 
1 202 LEU n 
1 203 PRO n 
1 204 ALA n 
1 205 SER n 
1 206 TRP n 
1 207 VAL n 
1 208 VAL n 
1 209 GLY n 
1 210 ASP n 
1 211 LYS n 
1 212 THR n 
1 213 GLY n 
1 214 SER n 
1 215 GLY n 
1 216 GLY n 
1 217 TYR n 
1 218 GLY n 
1 219 THR n 
1 220 THR n 
1 221 ASN n 
1 222 ASP n 
1 223 ILE n 
1 224 ALA n 
1 225 VAL n 
1 226 ILE n 
1 227 TRP n 
1 228 PRO n 
1 229 LYS n 
1 230 ASP n 
1 231 ARG n 
1 232 ALA n 
1 233 PRO n 
1 234 LEU n 
1 235 ILE n 
1 236 LEU n 
1 237 VAL n 
1 238 THR n 
1 239 TYR n 
1 240 PHE n 
1 241 THR n 
1 242 GLN n 
1 243 PRO n 
1 244 GLN n 
1 245 PRO n 
1 246 LYS n 
1 247 ALA n 
1 248 GLU n 
1 249 SER n 
1 250 ARG n 
1 251 ARG n 
1 252 ASP n 
1 253 VAL n 
1 254 LEU n 
1 255 ALA n 
1 256 SER n 
1 257 ALA n 
1 258 ALA n 
1 259 LYS n 
1 260 ILE n 
1 261 VAL n 
1 262 THR n 
1 263 ASP n 
1 264 GLY n 
1 265 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   265 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 blaCTX-M-15 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Klebsiella pneumoniae' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     573 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              Solu 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                                    ? 
'C3 H7 N O2'             89.093  
ARG 'L-peptide linking' y ARGININE                                                                                   ? 
'C6 H15 N4 O2 1'         175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                                 ? 
'C4 H8 N2 O3'            132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                            ? 
'C4 H7 N O4'             133.103 
CL  non-polymer         . 'CHLORIDE ION'                                                                             ? 'Cl -1' 
35.453  
CYS 'L-peptide linking' y CYSTEINE                                                                                   ? 
'C3 H7 N O2 S'           121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                                                  ? 
'C5 H10 N2 O3'           146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                            ? 
'C5 H9 N O4'             147.129 
GLY 'peptide linking'   y GLYCINE                                                                                    ? 
'C2 H5 N O2'             75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                                  ? 
'C6 H10 N3 O2 1'         156.162 
HOH non-polymer         . WATER                                                                                      ? 'H2 O' 
18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                                                                 ? 
'C6 H13 N O2'            131.173 
LEU 'L-peptide linking' y LEUCINE                                                                                    ? 
'C6 H13 N O2'            131.173 
LYS 'L-peptide linking' y LYSINE                                                                                     ? 
'C6 H15 N2 O2 1'         147.195 
MET 'L-peptide linking' y METHIONINE                                                                                 ? 
'C5 H11 N O2 S'          149.211 
NA  non-polymer         . 'SODIUM ION'                                                                               ? 'Na 1' 
22.990  
PHE 'L-peptide linking' y PHENYLALANINE                                                                              ? 
'C9 H11 N O2'            165.189 
PRO 'L-peptide linking' y PROLINE                                                                                    ? 
'C5 H9 N O2'             115.130 
SER 'L-peptide linking' y SERINE                                                                                     ? 
'C3 H7 N O3'             105.093 
SO4 non-polymer         . 'SULFATE ION'                                                                              ? 'O4 S -2' 
96.063  
THR 'L-peptide linking' y THREONINE                                                                                  ? 
'C4 H9 N O3'             119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                                 ? 
'C11 H12 N2 O2'          204.225 
TYR 'L-peptide linking' y TYROSINE                                                                                   ? 
'C9 H11 N O3'            181.189 
VAL 'L-peptide linking' y VALINE                                                                                     ? 
'C5 H11 N O2'            117.146 
XQN non-polymer         . '4-chloranyl-N-[[(3S)-1-oxidanyl-3H-2,1$l^{4}-benzoxaborol-3-yl]methyl]benzenesulfonamide' ? 
'C14 H13 B Cl N O4 S -1' 337.586 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   24  ?   ?   ?   A . n 
A 1 2   PRO 2   25  ?   ?   ?   A . n 
A 1 3   GLN 3   26  ?   ?   ?   A . n 
A 1 4   THR 4   27  27  THR THR A . n 
A 1 5   ALA 5   28  28  ALA ALA A . n 
A 1 6   ASP 6   29  29  ASP ASP A . n 
A 1 7   VAL 7   30  30  VAL VAL A . n 
A 1 8   GLN 8   31  31  GLN GLN A . n 
A 1 9   GLN 9   32  32  GLN GLN A . n 
A 1 10  LYS 10  33  33  LYS LYS A . n 
A 1 11  LEU 11  34  34  LEU LEU A . n 
A 1 12  ALA 12  35  35  ALA ALA A . n 
A 1 13  GLU 13  36  36  GLU GLU A . n 
A 1 14  LEU 14  37  37  LEU LEU A . n 
A 1 15  GLU 15  38  38  GLU GLU A . n 
A 1 16  ARG 16  39  39  ARG ARG A . n 
A 1 17  GLN 17  40  40  GLN GLN A . n 
A 1 18  SER 18  41  41  SER SER A . n 
A 1 19  GLY 19  42  42  GLY GLY A . n 
A 1 20  GLY 20  43  43  GLY GLY A . n 
A 1 21  ARG 21  44  44  ARG ARG A . n 
A 1 22  LEU 22  45  45  LEU LEU A . n 
A 1 23  GLY 23  46  46  GLY GLY A . n 
A 1 24  VAL 24  47  47  VAL VAL A . n 
A 1 25  ALA 25  48  48  ALA ALA A . n 
A 1 26  LEU 26  49  49  LEU LEU A . n 
A 1 27  ILE 27  50  50  ILE ILE A . n 
A 1 28  ASN 28  51  51  ASN ASN A . n 
A 1 29  THR 29  52  52  THR THR A . n 
A 1 30  ALA 30  53  53  ALA ALA A . n 
A 1 31  ASP 31  54  54  ASP ASP A . n 
A 1 32  ASN 32  55  55  ASN ASN A . n 
A 1 33  SER 33  56  56  SER SER A . n 
A 1 34  GLN 34  57  57  GLN GLN A . n 
A 1 35  ILE 35  58  58  ILE ILE A . n 
A 1 36  LEU 36  59  59  LEU LEU A . n 
A 1 37  TYR 37  60  60  TYR TYR A . n 
A 1 38  ARG 38  61  61  ARG ARG A . n 
A 1 39  ALA 39  62  62  ALA ALA A . n 
A 1 40  ASP 40  63  63  ASP ASP A . n 
A 1 41  GLU 41  64  64  GLU GLU A . n 
A 1 42  ARG 42  65  65  ARG ARG A . n 
A 1 43  PHE 43  66  66  PHE PHE A . n 
A 1 44  ALA 44  67  67  ALA ALA A . n 
A 1 45  MET 45  68  68  MET MET A . n 
A 1 46  CYS 46  69  69  CYS CYS A . n 
A 1 47  SER 47  70  70  SER SER A . n 
A 1 48  THR 48  71  71  THR THR A . n 
A 1 49  SER 49  72  72  SER SER A . n 
A 1 50  LYS 50  73  73  LYS LYS A . n 
A 1 51  VAL 51  74  74  VAL VAL A . n 
A 1 52  MET 52  75  75  MET MET A . n 
A 1 53  ALA 53  76  76  ALA ALA A . n 
A 1 54  ALA 54  77  77  ALA ALA A . n 
A 1 55  ALA 55  78  78  ALA ALA A . n 
A 1 56  ALA 56  79  79  ALA ALA A . n 
A 1 57  VAL 57  80  80  VAL VAL A . n 
A 1 58  LEU 58  81  81  LEU LEU A . n 
A 1 59  LYS 59  82  82  LYS LYS A . n 
A 1 60  LYS 60  83  83  LYS LYS A . n 
A 1 61  SER 61  84  84  SER SER A . n 
A 1 62  GLU 62  85  85  GLU GLU A . n 
A 1 63  SER 63  86  86  SER SER A . n 
A 1 64  GLU 64  87  87  GLU GLU A . n 
A 1 65  PRO 65  88  88  PRO PRO A . n 
A 1 66  ASN 66  89  89  ASN ASN A . n 
A 1 67  LEU 67  90  90  LEU LEU A . n 
A 1 68  LEU 68  91  91  LEU LEU A . n 
A 1 69  ASN 69  92  92  ASN ASN A . n 
A 1 70  GLN 70  93  93  GLN GLN A . n 
A 1 71  ARG 71  94  94  ARG ARG A . n 
A 1 72  VAL 72  95  95  VAL VAL A . n 
A 1 73  GLU 73  96  96  GLU GLU A . n 
A 1 74  ILE 74  97  97  ILE ILE A . n 
A 1 75  LYS 75  98  98  LYS LYS A . n 
A 1 76  LYS 76  99  99  LYS LYS A . n 
A 1 77  SER 77  100 100 SER SER A . n 
A 1 78  ASP 78  101 101 ASP ASP A . n 
A 1 79  LEU 79  102 102 LEU LEU A . n 
A 1 80  VAL 80  103 103 VAL VAL A . n 
A 1 81  ASN 81  104 104 ASN ASN A . n 
A 1 82  TYR 82  105 105 TYR TYR A . n 
A 1 83  ASN 83  106 106 ASN ASN A . n 
A 1 84  PRO 84  107 107 PRO PRO A . n 
A 1 85  ILE 85  108 108 ILE ILE A . n 
A 1 86  ALA 86  109 109 ALA ALA A . n 
A 1 87  GLU 87  110 110 GLU GLU A . n 
A 1 88  LYS 88  111 111 LYS LYS A . n 
A 1 89  HIS 89  112 112 HIS HIS A . n 
A 1 90  VAL 90  113 113 VAL VAL A . n 
A 1 91  ASN 91  114 114 ASN ASN A . n 
A 1 92  GLY 92  115 115 GLY GLY A . n 
A 1 93  THR 93  116 116 THR THR A . n 
A 1 94  MET 94  117 117 MET MET A . n 
A 1 95  SER 95  118 118 SER SER A . n 
A 1 96  LEU 96  119 119 LEU LEU A . n 
A 1 97  ALA 97  120 120 ALA ALA A . n 
A 1 98  GLU 98  121 121 GLU GLU A . n 
A 1 99  LEU 99  122 122 LEU LEU A . n 
A 1 100 SER 100 123 123 SER SER A . n 
A 1 101 ALA 101 124 124 ALA ALA A . n 
A 1 102 ALA 102 125 125 ALA ALA A . n 
A 1 103 ALA 103 126 126 ALA ALA A . n 
A 1 104 LEU 104 127 127 LEU LEU A . n 
A 1 105 GLN 105 128 128 GLN GLN A . n 
A 1 106 TYR 106 129 129 TYR TYR A . n 
A 1 107 SER 107 130 130 SER SER A . n 
A 1 108 ASP 108 131 131 ASP ASP A . n 
A 1 109 ASN 109 132 132 ASN ASN A . n 
A 1 110 VAL 110 133 133 VAL VAL A . n 
A 1 111 ALA 111 134 134 ALA ALA A . n 
A 1 112 MET 112 135 135 MET MET A . n 
A 1 113 ASN 113 136 136 ASN ASN A . n 
A 1 114 LYS 114 137 137 LYS LYS A . n 
A 1 115 LEU 115 138 138 LEU LEU A . n 
A 1 116 ILE 116 139 139 ILE ILE A . n 
A 1 117 ALA 117 140 140 ALA ALA A . n 
A 1 118 HIS 118 141 141 HIS HIS A . n 
A 1 119 VAL 119 142 142 VAL VAL A . n 
A 1 120 GLY 120 143 143 GLY GLY A . n 
A 1 121 GLY 121 144 144 GLY GLY A . n 
A 1 122 PRO 122 145 145 PRO PRO A . n 
A 1 123 ALA 123 146 146 ALA ALA A . n 
A 1 124 SER 124 147 147 SER SER A . n 
A 1 125 VAL 125 148 148 VAL VAL A . n 
A 1 126 THR 126 149 149 THR THR A . n 
A 1 127 ALA 127 150 150 ALA ALA A . n 
A 1 128 PHE 128 151 151 PHE PHE A . n 
A 1 129 ALA 129 152 152 ALA ALA A . n 
A 1 130 ARG 130 153 153 ARG ARG A . n 
A 1 131 GLN 131 154 154 GLN GLN A . n 
A 1 132 LEU 132 155 155 LEU LEU A . n 
A 1 133 GLY 133 156 156 GLY GLY A . n 
A 1 134 ASP 134 157 157 ASP ASP A . n 
A 1 135 GLU 135 158 158 GLU GLU A . n 
A 1 136 THR 136 159 159 THR THR A . n 
A 1 137 PHE 137 160 160 PHE PHE A . n 
A 1 138 ARG 138 161 161 ARG ARG A . n 
A 1 139 LEU 139 162 162 LEU LEU A . n 
A 1 140 ASP 140 163 163 ASP ASP A . n 
A 1 141 ARG 141 164 164 ARG ARG A . n 
A 1 142 THR 142 165 165 THR THR A . n 
A 1 143 GLU 143 166 166 GLU GLU A . n 
A 1 144 PRO 144 167 167 PRO PRO A . n 
A 1 145 THR 145 168 168 THR THR A . n 
A 1 146 LEU 146 169 169 LEU LEU A . n 
A 1 147 ASN 147 170 170 ASN ASN A . n 
A 1 148 THR 148 171 171 THR THR A . n 
A 1 149 ALA 149 172 172 ALA ALA A . n 
A 1 150 ILE 150 173 173 ILE ILE A . n 
A 1 151 PRO 151 174 174 PRO PRO A . n 
A 1 152 GLY 152 175 175 GLY GLY A . n 
A 1 153 ASP 153 176 176 ASP ASP A . n 
A 1 154 PRO 154 177 177 PRO PRO A . n 
A 1 155 ARG 155 178 178 ARG ARG A . n 
A 1 156 ASP 156 179 179 ASP ASP A . n 
A 1 157 THR 157 180 180 THR THR A . n 
A 1 158 THR 158 181 181 THR THR A . n 
A 1 159 SER 159 182 182 SER SER A . n 
A 1 160 PRO 160 183 183 PRO PRO A . n 
A 1 161 ARG 161 184 184 ARG ARG A . n 
A 1 162 ALA 162 185 185 ALA ALA A . n 
A 1 163 MET 163 186 186 MET MET A . n 
A 1 164 ALA 164 187 187 ALA ALA A . n 
A 1 165 GLN 165 188 188 GLN GLN A . n 
A 1 166 THR 166 189 189 THR THR A . n 
A 1 167 LEU 167 190 190 LEU LEU A . n 
A 1 168 ARG 168 191 191 ARG ARG A . n 
A 1 169 ASN 169 192 192 ASN ASN A . n 
A 1 170 LEU 170 193 193 LEU LEU A . n 
A 1 171 THR 171 194 194 THR THR A . n 
A 1 172 LEU 172 195 195 LEU LEU A . n 
A 1 173 GLY 173 196 196 GLY GLY A . n 
A 1 174 LYS 174 197 197 LYS LYS A . n 
A 1 175 ALA 175 198 198 ALA ALA A . n 
A 1 176 LEU 176 199 199 LEU LEU A . n 
A 1 177 GLY 177 200 200 GLY GLY A . n 
A 1 178 ASP 178 201 201 ASP ASP A . n 
A 1 179 SER 179 202 202 SER SER A . n 
A 1 180 GLN 180 203 203 GLN GLN A . n 
A 1 181 ARG 181 204 204 ARG ARG A . n 
A 1 182 ALA 182 205 205 ALA ALA A . n 
A 1 183 GLN 183 206 206 GLN GLN A . n 
A 1 184 LEU 184 207 207 LEU LEU A . n 
A 1 185 VAL 185 208 208 VAL VAL A . n 
A 1 186 THR 186 209 209 THR THR A . n 
A 1 187 TRP 187 210 210 TRP TRP A . n 
A 1 188 MET 188 211 211 MET MET A . n 
A 1 189 LYS 189 212 212 LYS LYS A . n 
A 1 190 GLY 190 213 213 GLY GLY A . n 
A 1 191 ASN 191 214 214 ASN ASN A . n 
A 1 192 THR 192 215 215 THR THR A . n 
A 1 193 THR 193 216 216 THR THR A . n 
A 1 194 GLY 194 217 217 GLY GLY A . n 
A 1 195 ALA 195 218 218 ALA ALA A . n 
A 1 196 ALA 196 219 219 ALA ALA A . n 
A 1 197 SER 197 220 220 SER SER A . n 
A 1 198 ILE 198 221 221 ILE ILE A . n 
A 1 199 GLN 199 222 222 GLN GLN A . n 
A 1 200 ALA 200 223 223 ALA ALA A . n 
A 1 201 GLY 201 224 224 GLY GLY A . n 
A 1 202 LEU 202 225 225 LEU LEU A . n 
A 1 203 PRO 203 226 226 PRO PRO A . n 
A 1 204 ALA 204 227 227 ALA ALA A . n 
A 1 205 SER 205 228 228 SER SER A . n 
A 1 206 TRP 206 229 229 TRP TRP A . n 
A 1 207 VAL 207 230 230 VAL VAL A . n 
A 1 208 VAL 208 231 231 VAL VAL A . n 
A 1 209 GLY 209 232 232 GLY GLY A . n 
A 1 210 ASP 210 233 233 ASP ASP A . n 
A 1 211 LYS 211 234 234 LYS LYS A . n 
A 1 212 THR 212 235 235 THR THR A . n 
A 1 213 GLY 213 236 236 GLY GLY A . n 
A 1 214 SER 214 237 237 SER SER A . n 
A 1 215 GLY 215 238 238 GLY GLY A . n 
A 1 216 GLY 216 239 239 GLY GLY A . n 
A 1 217 TYR 217 240 240 TYR TYR A . n 
A 1 218 GLY 218 241 241 GLY GLY A . n 
A 1 219 THR 219 242 242 THR THR A . n 
A 1 220 THR 220 243 243 THR THR A . n 
A 1 221 ASN 221 244 244 ASN ASN A . n 
A 1 222 ASP 222 245 245 ASP ASP A . n 
A 1 223 ILE 223 246 246 ILE ILE A . n 
A 1 224 ALA 224 247 247 ALA ALA A . n 
A 1 225 VAL 225 248 248 VAL VAL A . n 
A 1 226 ILE 226 249 249 ILE ILE A . n 
A 1 227 TRP 227 250 250 TRP TRP A . n 
A 1 228 PRO 228 251 251 PRO PRO A . n 
A 1 229 LYS 229 252 252 LYS LYS A . n 
A 1 230 ASP 230 253 253 ASP ASP A . n 
A 1 231 ARG 231 254 254 ARG ARG A . n 
A 1 232 ALA 232 255 255 ALA ALA A . n 
A 1 233 PRO 233 256 256 PRO PRO A . n 
A 1 234 LEU 234 257 257 LEU LEU A . n 
A 1 235 ILE 235 258 258 ILE ILE A . n 
A 1 236 LEU 236 259 259 LEU LEU A . n 
A 1 237 VAL 237 260 260 VAL VAL A . n 
A 1 238 THR 238 261 261 THR THR A . n 
A 1 239 TYR 239 262 262 TYR TYR A . n 
A 1 240 PHE 240 263 263 PHE PHE A . n 
A 1 241 THR 241 264 264 THR THR A . n 
A 1 242 GLN 242 265 265 GLN GLN A . n 
A 1 243 PRO 243 266 266 PRO PRO A . n 
A 1 244 GLN 244 267 267 GLN GLN A . n 
A 1 245 PRO 245 268 268 PRO PRO A . n 
A 1 246 LYS 246 269 269 LYS LYS A . n 
A 1 247 ALA 247 270 270 ALA ALA A . n 
A 1 248 GLU 248 271 271 GLU GLU A . n 
A 1 249 SER 249 272 272 SER SER A . n 
A 1 250 ARG 250 273 273 ARG ARG A . n 
A 1 251 ARG 251 274 274 ARG ARG A . n 
A 1 252 ASP 252 275 275 ASP ASP A . n 
A 1 253 VAL 253 276 276 VAL VAL A . n 
A 1 254 LEU 254 277 277 LEU LEU A . n 
A 1 255 ALA 255 278 278 ALA ALA A . n 
A 1 256 SER 256 279 279 SER SER A . n 
A 1 257 ALA 257 280 280 ALA ALA A . n 
A 1 258 ALA 258 281 281 ALA ALA A . n 
A 1 259 LYS 259 282 282 LYS LYS A . n 
A 1 260 ILE 260 283 283 ILE ILE A . n 
A 1 261 VAL 261 284 284 VAL VAL A . n 
A 1 262 THR 262 285 285 THR THR A . n 
A 1 263 ASP 263 286 286 ASP ASP A . n 
A 1 264 GLY 264 287 287 GLY GLY A . n 
A 1 265 LEU 265 288 288 LEU LEU A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        XQN 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   XQN 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 XQN 1   301 301 XQN 412 A . 
C 3 SO4 1   302 4   SO4 SO4 A . 
D 3 SO4 1   303 5   SO4 SO4 A . 
E 3 SO4 1   304 6   SO4 SO4 A . 
F 4 CL  1   305 1   CL  CL  A . 
G 5 NA  1   306 1   NA  NA  A . 
H 5 NA  1   307 2   NA  NA  A . 
I 5 NA  1   308 3   NA  NA  A . 
J 6 HOH 1   401 50  HOH HOH A . 
J 6 HOH 2   402 132 HOH HOH A . 
J 6 HOH 3   403 150 HOH HOH A . 
J 6 HOH 4   404 115 HOH HOH A . 
J 6 HOH 5   405 39  HOH HOH A . 
J 6 HOH 6   406 100 HOH HOH A . 
J 6 HOH 7   407 215 HOH HOH A . 
J 6 HOH 8   408 124 HOH HOH A . 
J 6 HOH 9   409 16  HOH HOH A . 
J 6 HOH 10  410 146 HOH HOH A . 
J 6 HOH 11  411 96  HOH HOH A . 
J 6 HOH 12  412 147 HOH HOH A . 
J 6 HOH 13  413 47  HOH HOH A . 
J 6 HOH 14  414 140 HOH HOH A . 
J 6 HOH 15  415 90  HOH HOH A . 
J 6 HOH 16  416 38  HOH HOH A . 
J 6 HOH 17  417 155 HOH HOH A . 
J 6 HOH 18  418 99  HOH HOH A . 
J 6 HOH 19  419 167 HOH HOH A . 
J 6 HOH 20  420 44  HOH HOH A . 
J 6 HOH 21  421 111 HOH HOH A . 
J 6 HOH 22  422 37  HOH HOH A . 
J 6 HOH 23  423 17  HOH HOH A . 
J 6 HOH 24  424 29  HOH HOH A . 
J 6 HOH 25  425 138 HOH HOH A . 
J 6 HOH 26  426 21  HOH HOH A . 
J 6 HOH 27  427 158 HOH HOH A . 
J 6 HOH 28  428 3   HOH HOH A . 
J 6 HOH 29  429 32  HOH HOH A . 
J 6 HOH 30  430 119 HOH HOH A . 
J 6 HOH 31  431 8   HOH HOH A . 
J 6 HOH 32  432 55  HOH HOH A . 
J 6 HOH 33  433 40  HOH HOH A . 
J 6 HOH 34  434 85  HOH HOH A . 
J 6 HOH 35  435 6   HOH HOH A . 
J 6 HOH 36  436 126 HOH HOH A . 
J 6 HOH 37  437 213 HOH HOH A . 
J 6 HOH 38  438 62  HOH HOH A . 
J 6 HOH 39  439 10  HOH HOH A . 
J 6 HOH 40  440 26  HOH HOH A . 
J 6 HOH 41  441 11  HOH HOH A . 
J 6 HOH 42  442 54  HOH HOH A . 
J 6 HOH 43  443 4   HOH HOH A . 
J 6 HOH 44  444 15  HOH HOH A . 
J 6 HOH 45  445 56  HOH HOH A . 
J 6 HOH 46  446 35  HOH HOH A . 
J 6 HOH 47  447 46  HOH HOH A . 
J 6 HOH 48  448 72  HOH HOH A . 
J 6 HOH 49  449 23  HOH HOH A . 
J 6 HOH 50  450 7   HOH HOH A . 
J 6 HOH 51  451 14  HOH HOH A . 
J 6 HOH 52  452 20  HOH HOH A . 
J 6 HOH 53  453 22  HOH HOH A . 
J 6 HOH 54  454 68  HOH HOH A . 
J 6 HOH 55  455 61  HOH HOH A . 
J 6 HOH 56  456 76  HOH HOH A . 
J 6 HOH 57  457 128 HOH HOH A . 
J 6 HOH 58  458 13  HOH HOH A . 
J 6 HOH 59  459 91  HOH HOH A . 
J 6 HOH 60  460 135 HOH HOH A . 
J 6 HOH 61  461 34  HOH HOH A . 
J 6 HOH 62  462 12  HOH HOH A . 
J 6 HOH 63  463 2   HOH HOH A . 
J 6 HOH 64  464 58  HOH HOH A . 
J 6 HOH 65  465 153 HOH HOH A . 
J 6 HOH 66  466 112 HOH HOH A . 
J 6 HOH 67  467 143 HOH HOH A . 
J 6 HOH 68  468 151 HOH HOH A . 
J 6 HOH 69  469 174 HOH HOH A . 
J 6 HOH 70  470 81  HOH HOH A . 
J 6 HOH 71  471 106 HOH HOH A . 
J 6 HOH 72  472 154 HOH HOH A . 
J 6 HOH 73  473 164 HOH HOH A . 
J 6 HOH 74  474 148 HOH HOH A . 
J 6 HOH 75  475 122 HOH HOH A . 
J 6 HOH 76  476 87  HOH HOH A . 
J 6 HOH 77  477 5   HOH HOH A . 
J 6 HOH 78  478 82  HOH HOH A . 
J 6 HOH 79  479 42  HOH HOH A . 
J 6 HOH 80  480 114 HOH HOH A . 
J 6 HOH 81  481 9   HOH HOH A . 
J 6 HOH 82  482 33  HOH HOH A . 
J 6 HOH 83  483 60  HOH HOH A . 
J 6 HOH 84  484 57  HOH HOH A . 
J 6 HOH 85  485 97  HOH HOH A . 
J 6 HOH 86  486 139 HOH HOH A . 
J 6 HOH 87  487 120 HOH HOH A . 
J 6 HOH 88  488 31  HOH HOH A . 
J 6 HOH 89  489 116 HOH HOH A . 
J 6 HOH 90  490 77  HOH HOH A . 
J 6 HOH 91  491 184 HOH HOH A . 
J 6 HOH 92  492 66  HOH HOH A . 
J 6 HOH 93  493 113 HOH HOH A . 
J 6 HOH 94  494 25  HOH HOH A . 
J 6 HOH 95  495 149 HOH HOH A . 
J 6 HOH 96  496 1   HOH HOH A . 
J 6 HOH 97  497 134 HOH HOH A . 
J 6 HOH 98  498 75  HOH HOH A . 
J 6 HOH 99  499 108 HOH HOH A . 
J 6 HOH 100 500 65  HOH HOH A . 
J 6 HOH 101 501 181 HOH HOH A . 
J 6 HOH 102 502 52  HOH HOH A . 
J 6 HOH 103 503 168 HOH HOH A . 
J 6 HOH 104 504 86  HOH HOH A . 
J 6 HOH 105 505 63  HOH HOH A . 
J 6 HOH 106 506 199 HOH HOH A . 
J 6 HOH 107 507 136 HOH HOH A . 
J 6 HOH 108 508 214 HOH HOH A . 
J 6 HOH 109 509 53  HOH HOH A . 
J 6 HOH 110 510 185 HOH HOH A . 
J 6 HOH 111 511 51  HOH HOH A . 
J 6 HOH 112 512 117 HOH HOH A . 
J 6 HOH 113 513 102 HOH HOH A . 
J 6 HOH 114 514 133 HOH HOH A . 
J 6 HOH 115 515 73  HOH HOH A . 
J 6 HOH 116 516 48  HOH HOH A . 
J 6 HOH 117 517 105 HOH HOH A . 
J 6 HOH 118 518 157 HOH HOH A . 
J 6 HOH 119 519 84  HOH HOH A . 
J 6 HOH 120 520 30  HOH HOH A . 
J 6 HOH 121 521 93  HOH HOH A . 
J 6 HOH 122 522 203 HOH HOH A . 
J 6 HOH 123 523 83  HOH HOH A . 
J 6 HOH 124 524 45  HOH HOH A . 
J 6 HOH 125 525 28  HOH HOH A . 
J 6 HOH 126 526 162 HOH HOH A . 
J 6 HOH 127 527 144 HOH HOH A . 
J 6 HOH 128 528 69  HOH HOH A . 
J 6 HOH 129 529 92  HOH HOH A . 
J 6 HOH 130 530 24  HOH HOH A . 
J 6 HOH 131 531 212 HOH HOH A . 
J 6 HOH 132 532 64  HOH HOH A . 
J 6 HOH 133 533 78  HOH HOH A . 
J 6 HOH 134 534 80  HOH HOH A . 
J 6 HOH 135 535 179 HOH HOH A . 
J 6 HOH 136 536 27  HOH HOH A . 
J 6 HOH 137 537 41  HOH HOH A . 
J 6 HOH 138 538 166 HOH HOH A . 
J 6 HOH 139 539 118 HOH HOH A . 
J 6 HOH 140 540 19  HOH HOH A . 
J 6 HOH 141 541 89  HOH HOH A . 
J 6 HOH 142 542 205 HOH HOH A . 
J 6 HOH 143 543 18  HOH HOH A . 
J 6 HOH 144 544 161 HOH HOH A . 
J 6 HOH 145 545 169 HOH HOH A . 
J 6 HOH 146 546 70  HOH HOH A . 
J 6 HOH 147 547 123 HOH HOH A . 
J 6 HOH 148 548 130 HOH HOH A . 
J 6 HOH 149 549 71  HOH HOH A . 
J 6 HOH 150 550 74  HOH HOH A . 
J 6 HOH 151 551 104 HOH HOH A . 
J 6 HOH 152 552 107 HOH HOH A . 
J 6 HOH 153 553 109 HOH HOH A . 
J 6 HOH 154 554 187 HOH HOH A . 
J 6 HOH 155 555 49  HOH HOH A . 
J 6 HOH 156 556 210 HOH HOH A . 
J 6 HOH 157 557 216 HOH HOH A . 
J 6 HOH 158 558 129 HOH HOH A . 
J 6 HOH 159 559 36  HOH HOH A . 
J 6 HOH 160 560 188 HOH HOH A . 
J 6 HOH 161 561 173 HOH HOH A . 
J 6 HOH 162 562 180 HOH HOH A . 
J 6 HOH 163 563 127 HOH HOH A . 
J 6 HOH 164 564 94  HOH HOH A . 
J 6 HOH 165 565 171 HOH HOH A . 
J 6 HOH 166 566 191 HOH HOH A . 
J 6 HOH 167 567 208 HOH HOH A . 
J 6 HOH 168 568 121 HOH HOH A . 
J 6 HOH 169 569 43  HOH HOH A . 
J 6 HOH 170 570 176 HOH HOH A . 
J 6 HOH 171 571 160 HOH HOH A . 
J 6 HOH 172 572 175 HOH HOH A . 
J 6 HOH 173 573 182 HOH HOH A . 
J 6 HOH 174 574 211 HOH HOH A . 
J 6 HOH 175 575 218 HOH HOH A . 
J 6 HOH 176 576 98  HOH HOH A . 
J 6 HOH 177 577 190 HOH HOH A . 
J 6 HOH 178 578 178 HOH HOH A . 
J 6 HOH 179 579 125 HOH HOH A . 
J 6 HOH 180 580 204 HOH HOH A . 
J 6 HOH 181 581 207 HOH HOH A . 
J 6 HOH 182 582 196 HOH HOH A . 
J 6 HOH 183 583 79  HOH HOH A . 
J 6 HOH 184 584 186 HOH HOH A . 
J 6 HOH 185 585 200 HOH HOH A . 
J 6 HOH 186 586 198 HOH HOH A . 
J 6 HOH 187 587 170 HOH HOH A . 
J 6 HOH 188 588 202 HOH HOH A . 
J 6 HOH 189 589 152 HOH HOH A . 
J 6 HOH 190 590 189 HOH HOH A . 
J 6 HOH 191 591 219 HOH HOH A . 
J 6 HOH 192 592 163 HOH HOH A . 
J 6 HOH 193 593 110 HOH HOH A . 
J 6 HOH 194 594 137 HOH HOH A . 
J 6 HOH 195 595 221 HOH HOH A . 
J 6 HOH 196 596 59  HOH HOH A . 
J 6 HOH 197 597 195 HOH HOH A . 
J 6 HOH 198 598 95  HOH HOH A . 
J 6 HOH 199 599 101 HOH HOH A . 
J 6 HOH 200 600 220 HOH HOH A . 
J 6 HOH 201 601 217 HOH HOH A . 
J 6 HOH 202 602 67  HOH HOH A . 
J 6 HOH 203 603 193 HOH HOH A . 
J 6 HOH 204 604 131 HOH HOH A . 
J 6 HOH 205 605 141 HOH HOH A . 
J 6 HOH 206 606 142 HOH HOH A . 
J 6 HOH 207 607 103 HOH HOH A . 
J 6 HOH 208 608 172 HOH HOH A . 
J 6 HOH 209 609 209 HOH HOH A . 
J 6 HOH 210 610 201 HOH HOH A . 
J 6 HOH 211 611 192 HOH HOH A . 
J 6 HOH 212 612 183 HOH HOH A . 
J 6 HOH 213 613 206 HOH HOH A . 
J 6 HOH 214 614 194 HOH HOH A . 
J 6 HOH 215 615 145 HOH HOH A . 
J 6 HOH 216 616 156 HOH HOH A . 
J 6 HOH 217 617 159 HOH HOH A . 
J 6 HOH 218 618 88  HOH HOH A . 
J 6 HOH 219 619 197 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .           3 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R31 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     44.490 
_cell.length_a_esd                 ? 
_cell.length_b                     45.580 
_cell.length_b_esd                 ? 
_cell.length_c                     117.650 
_cell.length_c_esd                 ? 
_cell.volume                       238577.047 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R31 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R31 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.11 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          41.65 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '2.0 M ammonium sulphate, 0.1 M Tris 8.0' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            292.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-07-16 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.6741 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.6741 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          19.13 
_reflns.entry_id                                       8R31 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.65 
_reflns.d_resolution_low                               35.48 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     29612 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.3 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.2 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.078 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.65 
_reflns_shell.d_res_low                                     1.69 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.9 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2163 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               13.7 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.943 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.293 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100.0 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               24.96 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8R31 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.65 
_refine.ls_d_res_low                             35.48 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     29540 
_refine.ls_number_reflns_R_free                  1460 
_refine.ls_number_reflns_R_work                  28080 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.80 
_refine.ls_percent_reflns_R_free                 4.94 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1768 
_refine.ls_R_factor_R_free                       0.2119 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1750 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'FOURIER SYNTHESIS' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 22.4114 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2104 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.65 
_refine_hist.d_res_low                        35.48 
_refine_hist.number_atoms_solvent             219 
_refine_hist.number_atoms_total               2223 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1963 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         41 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0091  ? 2114 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0612  ? 2884 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0573  ? 331  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0122  ? 381  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 11.8301 ? 811  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.65 1.71  . . 131 2763 99.79  . . . . 0.3063 . . . . . . . . . . . 0.3455 
'X-RAY DIFFRACTION' 1.71 1.78  . . 145 2779 99.86  . . . . 0.2961 . . . . . . . . . . . 0.3616 
'X-RAY DIFFRACTION' 1.78 1.86  . . 143 2774 99.93  . . . . 0.2513 . . . . . . . . . . . 0.3041 
'X-RAY DIFFRACTION' 1.86 1.96  . . 150 2738 99.83  . . . . 0.2188 . . . . . . . . . . . 0.2343 
'X-RAY DIFFRACTION' 1.96 2.08  . . 154 2780 100.00 . . . . 0.1885 . . . . . . . . . . . 0.2418 
'X-RAY DIFFRACTION' 2.08 2.24  . . 157 2774 100.00 . . . . 0.1693 . . . . . . . . . . . 0.2145 
'X-RAY DIFFRACTION' 2.24 2.46  . . 148 2805 99.80  . . . . 0.1479 . . . . . . . . . . . 0.1979 
'X-RAY DIFFRACTION' 2.46 2.82  . . 137 2796 98.82  . . . . 0.1410 . . . . . . . . . . . 0.1783 
'X-RAY DIFFRACTION' 2.82 3.55  . . 119 2887 100.00 . . . . 0.1354 . . . . . . . . . . . 0.1631 
'X-RAY DIFFRACTION' 3.55 35.48 . . 176 2984 99.97  . . . . 0.1715 . . . . . . . . . . . 0.1952 
# 
_struct.entry_id                     8R31 
_struct.title                        'Structure of CTX-M-15 complexed with benzoxaborole AK-412' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R31 
_struct_keywords.text            'Inhibitor, beta-lactamase, SBL, antibiotic resistance, boronate, ANTIMICROBIAL PROTEIN' 
_struct_keywords.pdbx_keywords   'ANTIMICROBIAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 4 ? 
G N N 5 ? 
H N N 5 ? 
I N N 5 ? 
J N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    G3G192_KLEPN 
_struct_ref.pdbx_db_accession          G3G192 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;QTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLVNY
NPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRA
MAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ
PQPKAESRRDVLASAAKIVTDGL
;
_struct_ref.pdbx_align_begin           49 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8R31 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 3 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 265 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             G3G192 
_struct_ref_seq.db_align_beg                  49 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  311 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       26 
_struct_ref_seq.pdbx_auth_seq_align_end       288 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8R31 GLY A 1 ? UNP G3G192 ? ? 'expression tag' 24 1 
1 8R31 PRO A 2 ? UNP G3G192 ? ? 'expression tag' 25 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 570   ? 
1 MORE         -39   ? 
1 'SSA (A^2)'  11050 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 4   ? GLY A 19  ? THR A 27  GLY A 42  1 ? 16 
HELX_P HELX_P2  AA2 CYS A 46  ? THR A 48  ? CYS A 69  THR A 71  5 ? 3  
HELX_P HELX_P3  AA3 SER A 49  ? GLU A 62  ? SER A 72  GLU A 85  1 ? 14 
HELX_P HELX_P4  AA4 ASN A 66  ? ASN A 69  ? ASN A 89  ASN A 92  5 ? 4  
HELX_P HELX_P5  AA5 LYS A 75  ? LEU A 79  ? LYS A 98  LEU A 102 5 ? 5  
HELX_P HELX_P6  AA6 ILE A 85  ? VAL A 90  ? ILE A 108 VAL A 113 5 ? 6  
HELX_P HELX_P7  AA7 LEU A 96  ? TYR A 106 ? LEU A 119 TYR A 129 1 ? 11 
HELX_P HELX_P8  AA8 ASP A 108 ? GLY A 120 ? ASP A 131 GLY A 143 1 ? 13 
HELX_P HELX_P9  AA9 GLY A 121 ? LEU A 132 ? GLY A 144 LEU A 155 1 ? 12 
HELX_P HELX_P10 AB1 PRO A 144 ? THR A 148 ? PRO A 167 THR A 171 5 ? 5  
HELX_P HELX_P11 AB2 SER A 159 ? LEU A 172 ? SER A 182 LEU A 195 1 ? 14 
HELX_P HELX_P12 AB3 GLY A 177 ? GLY A 190 ? GLY A 200 GLY A 213 1 ? 14 
HELX_P HELX_P13 AB4 SER A 197 ? LEU A 202 ? SER A 220 LEU A 225 5 ? 6  
HELX_P HELX_P14 AB5 ARG A 250 ? ASP A 263 ? ARG A 273 ASP A 286 1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale none ? A SER 47  OG  ? ? ? 1_555 B XQN . B2 ? ? A SER 70  A XQN 301 1_555 ? ? ? ? ? ? ? 1.443 ? ? 
metalc1 metalc ?    ? A ASP 134 OD2 ? ? ? 1_555 G NA  . NA ? ? A ASP 157 A NA  306 1_555 ? ? ? ? ? ? ? 2.675 ? ? 
metalc2 metalc ?    ? A THR 158 OG1 ? ? ? 1_555 G NA  . NA ? ? A THR 181 A NA  306 1_555 ? ? ? ? ? ? ? 2.659 ? ? 
metalc3 metalc ?    ? A GLY 194 O   ? ? ? 1_555 H NA  . NA ? ? A GLY 217 A NA  307 1_555 ? ? ? ? ? ? ? 2.775 ? ? 
metalc4 metalc ?    ? A THR 212 OG1 ? ? ? 1_555 I NA  . NA ? ? A THR 235 A NA  308 1_555 ? ? ? ? ? ? ? 2.961 ? ? 
metalc5 metalc ?    ? A ASP 222 OD2 ? ? ? 1_555 H NA  . NA ? ? A ASP 245 A NA  307 1_555 ? ? ? ? ? ? ? 2.764 ? ? 
metalc6 metalc ?    ? I NA  .   NA  ? ? ? 1_555 J HOH . O  ? ? A NA  308 A HOH 515 1_555 ? ? ? ? ? ? ? 3.035 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OD2 ? A ASP 134 ? A ASP 157 ? 1_555 NA ? G NA . ? A NA 306 ? 1_555 OG1 ? A THR 158 ? A THR 181 ? 1_555 121.9 ? 
2 O   ? A GLY 194 ? A GLY 217 ? 1_555 NA ? H NA . ? A NA 307 ? 1_555 OD2 ? A ASP 222 ? A ASP 245 ? 1_555 108.3 ? 
3 OG1 ? A THR 212 ? A THR 235 ? 1_555 NA ? I NA . ? A NA 308 ? 1_555 O   ? J HOH .   ? A HOH 515 ? 1_555 90.0  ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      XQN 
_pdbx_modification_feature.label_asym_id                      B 
_pdbx_modification_feature.label_seq_id                       . 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     SER 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      47 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       XQN 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        301 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      SER 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       70 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               B2 
_pdbx_modification_feature.modified_residue_id_linking_atom   OG 
_pdbx_modification_feature.modified_residue_id                SER 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        XQN 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Covalent chemical modification' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLU 
_struct_mon_prot_cis.label_seq_id           143 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLU 
_struct_mon_prot_cis.auth_seq_id            166 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    144 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     167 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       4.71 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 33  ? TYR A 37  ? SER A 56  TYR A 60  
AA1 2 ARG A 21  ? ASN A 28  ? ARG A 44  ASN A 51  
AA1 3 LEU A 234 ? THR A 241 ? LEU A 257 THR A 264 
AA1 4 THR A 219 ? TRP A 227 ? THR A 242 TRP A 250 
AA1 5 VAL A 207 ? GLY A 215 ? VAL A 230 GLY A 238 
AA2 1 PHE A 43  ? ALA A 44  ? PHE A 66  ALA A 67  
AA2 2 THR A 157 ? THR A 158 ? THR A 180 THR A 181 
AA3 1 ARG A 71  ? GLU A 73  ? ARG A 94  GLU A 96  
AA3 2 THR A 93  ? SER A 95  ? THR A 116 SER A 118 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ILE A 35  ? O ILE A 58  N LEU A 26  ? N LEU A 49  
AA1 2 3 N GLY A 23  ? N GLY A 46  O TYR A 239 ? O TYR A 262 
AA1 3 4 O LEU A 234 ? O LEU A 257 N ILE A 226 ? N ILE A 249 
AA1 4 5 O ASN A 221 ? O ASN A 244 N GLY A 213 ? N GLY A 236 
AA2 1 2 N PHE A 43  ? N PHE A 66  O THR A 158 ? O THR A 181 
AA3 1 2 N VAL A 72  ? N VAL A 95  O MET A 94  ? O MET A 117 
# 
_pdbx_entry_details.entry_id                   8R31 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 HZ3 A LYS 99  ? ? O    A HOH 405 ? ? 1.46 
2  1 OD1 A ASP 201 ? ? HH22 A ARG 204 ? B 1.47 
3  1 O   A LEU 81  ? ? HG   A SER 84  ? ? 1.60 
4  1 O   A HOH 538 ? ? O    A HOH 562 ? ? 2.03 
5  1 O   A HOH 465 ? ? O    A HOH 573 ? ? 2.11 
6  1 O   A HOH 523 ? ? O    A HOH 539 ? ? 2.14 
7  1 O   A HOH 560 ? ? O    A HOH 584 ? ? 2.16 
8  1 O   A HOH 486 ? ? O    A HOH 594 ? ? 2.17 
9  1 OD1 A ASP 201 ? ? NH2  A ARG 204 ? B 2.17 
10 1 O   A HOH 565 ? ? O    A HOH 603 ? ? 2.17 
11 1 OE1 A GLU 110 ? ? O    A HOH 401 ? ? 2.17 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    HOH 
_pdbx_validate_symm_contact.auth_seq_id_1     487 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O 
_pdbx_validate_symm_contact.auth_asym_id_2    A 
_pdbx_validate_symm_contact.auth_comp_id_2    HOH 
_pdbx_validate_symm_contact.auth_seq_id_2     582 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   4_445 
_pdbx_validate_symm_contact.dist              2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 CYS A 69  ? ? 47.50   -141.68 
2 1 VAL A 103 ? ? -123.74 -132.13 
3 1 TYR A 105 ? ? -166.26 95.07   
4 1 SER A 220 ? ? -104.56 -123.40 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined 5.52242975386  -21.8163997904 4.1690264071  0.233322205367 ? 0.0265012907236   ? 0.035008930355   
? 0.224807470374 ? -0.0281726816333   ? 0.224777113744  ? 4.70616345556 ? 3.71402512503   ? -4.2757446238   ? 4.22397082957  ? 
-2.5452738112   ? 5.67790730835  ? -0.428713260205  ? 0.287305631408  ? -0.717470366397  ? -0.675515560853  ? 0.131112948054  ? 
-0.629602674762    ? 0.645588806378   ? 0.129205920344   ? 0.294599459952   ? 
2 'X-RAY DIFFRACTION' ? refined -1.95054637429 -14.9361994049 21.6024967588 0.166804161155 ? 0.00448292186938  ? -0.0136951702146 
? 0.160864265882 ? 0.0172152902542    ? 0.0967266018918 ? 1.65126140265 ? -0.261859298859 ? -0.584799011305 ? 1.76111775521  ? 
0.389434602236  ? 1.2313355267   ? -0.0740639515954 ? -0.183749701131 ? -0.0861040656231 ? 0.193210220037   ? 0.0315604081296 ? 
0.0515996762847    ? 0.134643878319   ? 0.133811981559   ? 0.0416975370636  ? 
3 'X-RAY DIFFRACTION' ? refined -17.0963163743 2.41809053696  29.9899098804 0.249233845587 ? 0.0217207613035   ? 0.0777504547002  
? 0.218026063299 ? -0.0572061713011   ? 0.232734037763  ? 5.86203333975 ? 3.09605047386   ? -1.50323015866  ? 2.00105221983  ? 
-4.95525343048  ? 5.5668557787   ? 0.188306398724   ? -0.32602768674  ? 0.286592265489   ? 1.11184049954    ? 0.240268028753  ? 
1.06123740358      ? -0.641448512176  ? -0.345950660928  ? -0.422280341964  ? 
4 'X-RAY DIFFRACTION' ? refined -16.1460748328 5.98620838742  16.7552138739 0.240860334665 ? 0.0346260331826   ? -0.0663979533327 
? 0.18324312289  ? 0.0377391481977    ? 0.268639343442  ? 3.58905062444 ? -0.381484660309 ? -3.48384546768  ? 6.75348228719  ? 
3.90213586929   ? 9.50949684785  ? 0.0703553406545  ? 0.390314104961  ? 0.210775241621   ? -0.46918571802   ? -0.171014487133 ? 
0.806621357024     ? -0.618867931858  ? -0.524861430552  ? 0.0997810419041  ? 
5 'X-RAY DIFFRACTION' ? refined -3.09062821033 -6.85386141874 22.8484515273 0.167913358291 ? -0.00879301456003 ? 0.00567292509531 
? 0.171808721985 ? -3.57125969504e-06 ? 0.111498340598  ? 1.10807035117 ? -0.285636646814 ? -0.142475040943 ? 1.88660890339  ? 
0.284129768753  ? 0.480499916942 ? 0.00309202376111 ? -0.123139734262 ? 0.0213205375837  ? 0.100835394602   ? 0.0228506027524 ? 
-0.000704158769864 ? -0.0475888825663 ? 0.0656693230618  ? -0.0252529563909 ? 
6 'X-RAY DIFFRACTION' ? refined -14.0638773979 -17.9016906531 25.962390159  0.172129650045 ? -0.0497787463423  ? 0.0187629945886  
? 0.133842997251 ? 0.0120959265481    ? 0.188731146874  ? 4.70717763931 ? -2.66825298562  ? -0.333812718183 ? 4.31234449461  ? 
0.0104668276069 ? 6.14123538853  ? 0.0277705666263  ? -0.183903820367 ? -0.47147584567   ? 0.316343091715   ? 0.125601450674  ? 
0.570239278702     ? 0.434901631689   ? -0.315814882575  ? -0.154092947757  ? 
7 'X-RAY DIFFRACTION' ? refined -8.78311467592 -14.9148955543 9.77869274938 0.17640290701  ? 0.00552071956112  ? -0.0142752273023 
? 0.189029811142 ? -0.000415629307357 ? 0.161439373555  ? 1.12318716014 ? -0.106286685139 ? 0.225618981567  ? 0.980331370527 ? 
0.361960657259  ? 1.84966184229  ? 0.00164064380292 ? 0.0234186735182 ? 0.018140469705   ? -0.0760461475153 ? 0.0106332860712 ? 
0.186882761695     ? 0.0381237086975  ? -0.205454441601  ? -0.0136824631394 ? 
8 'X-RAY DIFFRACTION' ? refined -2.55370667536 -15.8058689375 7.75258050422 0.215352779014 ? 0.0220567034786   ? 0.0337213347146  
? 0.168744801497 ? -0.0386234991858   ? 0.160729279432  ? 5.02028454319 ? 5.61081605385   ? -2.88473187958  ? 2.00564489486  ? 
-4.43119484454  ? 3.89587397311  ? -0.156924146277  ? 0.242317425078  ? 0.0257963306646  ? -0.669513473953  ? 0.240491461954  ? 
0.146432222742     ? 0.276584779239   ? -0.0810219897475 ? -0.0638066158394 ? 
9 'X-RAY DIFFRACTION' ? refined -3.65497541343 -21.5552249216 3.30288745016 0.195057181062 ? -0.019591595329   ? -0.01738425381   
? 0.202450227073 ? -0.0397480638312   ? 0.125224662187  ? 7.23425134927 ? -2.08279640045  ? -1.83662080376  ? 2.00007527076  ? 
-0.212492374256 ? 9.55366581692  ? -0.144101398632  ? 0.35408660428   ? -0.49110633607   ? -0.82064154219   ? 0.125182240532  ? 
0.257447852295     ? 0.781083014904   ? -0.261483305563  ? 0.0200247169088  ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 A 1   A 27  ? A 25  A 51  ? ? 
;chain 'A' and (resid 27 through 51 )
;
2 'X-RAY DIFFRACTION' 2 A 26  A 52  ? A 60  A 86  ? ? 
;chain 'A' and (resid 52 through 86 )
;
3 'X-RAY DIFFRACTION' 3 A 61  A 87  ? A 75  A 101 ? ? 
;chain 'A' and (resid 87 through 101 )
;
4 'X-RAY DIFFRACTION' 4 A 76  A 102 ? A 89  A 115 ? ? 
;chain 'A' and (resid 102 through 115 )
;
5 'X-RAY DIFFRACTION' 5 A 90  A 116 ? A 168 A 194 ? ? 
;chain 'A' and (resid 116 through 194 )
;
6 'X-RAY DIFFRACTION' 6 A 169 A 195 ? A 186 A 212 ? ? 
;chain 'A' and (resid 195 through 212 )
;
7 'X-RAY DIFFRACTION' 7 A 187 A 213 ? A 224 A 250 ? ? 
;chain 'A' and (resid 213 through 250 )
;
8 'X-RAY DIFFRACTION' 8 A 225 A 251 ? A 247 A 273 ? ? 
;chain 'A' and (resid 251 through 273 )
;
9 'X-RAY DIFFRACTION' 9 A 248 A 274 ? A 262 A 288 ? ? 
;chain 'A' and (resid 274 through 288 )
;
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLY 24 ? A GLY 1 
2 1 Y 1 A PRO 25 ? A PRO 2 
3 1 Y 1 A GLN 26 ? A GLN 3 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
HOH O    O  N N 159 
HOH H1   H  N N 160 
HOH H2   H  N N 161 
ILE N    N  N N 162 
ILE CA   C  N S 163 
ILE C    C  N N 164 
ILE O    O  N N 165 
ILE CB   C  N S 166 
ILE CG1  C  N N 167 
ILE CG2  C  N N 168 
ILE CD1  C  N N 169 
ILE OXT  O  N N 170 
ILE H    H  N N 171 
ILE H2   H  N N 172 
ILE HA   H  N N 173 
ILE HB   H  N N 174 
ILE HG12 H  N N 175 
ILE HG13 H  N N 176 
ILE HG21 H  N N 177 
ILE HG22 H  N N 178 
ILE HG23 H  N N 179 
ILE HD11 H  N N 180 
ILE HD12 H  N N 181 
ILE HD13 H  N N 182 
ILE HXT  H  N N 183 
LEU N    N  N N 184 
LEU CA   C  N S 185 
LEU C    C  N N 186 
LEU O    O  N N 187 
LEU CB   C  N N 188 
LEU CG   C  N N 189 
LEU CD1  C  N N 190 
LEU CD2  C  N N 191 
LEU OXT  O  N N 192 
LEU H    H  N N 193 
LEU H2   H  N N 194 
LEU HA   H  N N 195 
LEU HB2  H  N N 196 
LEU HB3  H  N N 197 
LEU HG   H  N N 198 
LEU HD11 H  N N 199 
LEU HD12 H  N N 200 
LEU HD13 H  N N 201 
LEU HD21 H  N N 202 
LEU HD22 H  N N 203 
LEU HD23 H  N N 204 
LEU HXT  H  N N 205 
LYS N    N  N N 206 
LYS CA   C  N S 207 
LYS C    C  N N 208 
LYS O    O  N N 209 
LYS CB   C  N N 210 
LYS CG   C  N N 211 
LYS CD   C  N N 212 
LYS CE   C  N N 213 
LYS NZ   N  N N 214 
LYS OXT  O  N N 215 
LYS H    H  N N 216 
LYS H2   H  N N 217 
LYS HA   H  N N 218 
LYS HB2  H  N N 219 
LYS HB3  H  N N 220 
LYS HG2  H  N N 221 
LYS HG3  H  N N 222 
LYS HD2  H  N N 223 
LYS HD3  H  N N 224 
LYS HE2  H  N N 225 
LYS HE3  H  N N 226 
LYS HZ1  H  N N 227 
LYS HZ2  H  N N 228 
LYS HZ3  H  N N 229 
LYS HXT  H  N N 230 
MET N    N  N N 231 
MET CA   C  N S 232 
MET C    C  N N 233 
MET O    O  N N 234 
MET CB   C  N N 235 
MET CG   C  N N 236 
MET SD   S  N N 237 
MET CE   C  N N 238 
MET OXT  O  N N 239 
MET H    H  N N 240 
MET H2   H  N N 241 
MET HA   H  N N 242 
MET HB2  H  N N 243 
MET HB3  H  N N 244 
MET HG2  H  N N 245 
MET HG3  H  N N 246 
MET HE1  H  N N 247 
MET HE2  H  N N 248 
MET HE3  H  N N 249 
MET HXT  H  N N 250 
NA  NA   NA N N 251 
PHE N    N  N N 252 
PHE CA   C  N S 253 
PHE C    C  N N 254 
PHE O    O  N N 255 
PHE CB   C  N N 256 
PHE CG   C  Y N 257 
PHE CD1  C  Y N 258 
PHE CD2  C  Y N 259 
PHE CE1  C  Y N 260 
PHE CE2  C  Y N 261 
PHE CZ   C  Y N 262 
PHE OXT  O  N N 263 
PHE H    H  N N 264 
PHE H2   H  N N 265 
PHE HA   H  N N 266 
PHE HB2  H  N N 267 
PHE HB3  H  N N 268 
PHE HD1  H  N N 269 
PHE HD2  H  N N 270 
PHE HE1  H  N N 271 
PHE HE2  H  N N 272 
PHE HZ   H  N N 273 
PHE HXT  H  N N 274 
PRO N    N  N N 275 
PRO CA   C  N S 276 
PRO C    C  N N 277 
PRO O    O  N N 278 
PRO CB   C  N N 279 
PRO CG   C  N N 280 
PRO CD   C  N N 281 
PRO OXT  O  N N 282 
PRO H    H  N N 283 
PRO HA   H  N N 284 
PRO HB2  H  N N 285 
PRO HB3  H  N N 286 
PRO HG2  H  N N 287 
PRO HG3  H  N N 288 
PRO HD2  H  N N 289 
PRO HD3  H  N N 290 
PRO HXT  H  N N 291 
SER N    N  N N 292 
SER CA   C  N S 293 
SER C    C  N N 294 
SER O    O  N N 295 
SER CB   C  N N 296 
SER OG   O  N N 297 
SER OXT  O  N N 298 
SER H    H  N N 299 
SER H2   H  N N 300 
SER HA   H  N N 301 
SER HB2  H  N N 302 
SER HB3  H  N N 303 
SER HG   H  N N 304 
SER HXT  H  N N 305 
SO4 S    S  N N 306 
SO4 O1   O  N N 307 
SO4 O2   O  N N 308 
SO4 O3   O  N N 309 
SO4 O4   O  N N 310 
THR N    N  N N 311 
THR CA   C  N S 312 
THR C    C  N N 313 
THR O    O  N N 314 
THR CB   C  N R 315 
THR OG1  O  N N 316 
THR CG2  C  N N 317 
THR OXT  O  N N 318 
THR H    H  N N 319 
THR H2   H  N N 320 
THR HA   H  N N 321 
THR HB   H  N N 322 
THR HG1  H  N N 323 
THR HG21 H  N N 324 
THR HG22 H  N N 325 
THR HG23 H  N N 326 
THR HXT  H  N N 327 
TRP N    N  N N 328 
TRP CA   C  N S 329 
TRP C    C  N N 330 
TRP O    O  N N 331 
TRP CB   C  N N 332 
TRP CG   C  Y N 333 
TRP CD1  C  Y N 334 
TRP CD2  C  Y N 335 
TRP NE1  N  Y N 336 
TRP CE2  C  Y N 337 
TRP CE3  C  Y N 338 
TRP CZ2  C  Y N 339 
TRP CZ3  C  Y N 340 
TRP CH2  C  Y N 341 
TRP OXT  O  N N 342 
TRP H    H  N N 343 
TRP H2   H  N N 344 
TRP HA   H  N N 345 
TRP HB2  H  N N 346 
TRP HB3  H  N N 347 
TRP HD1  H  N N 348 
TRP HE1  H  N N 349 
TRP HE3  H  N N 350 
TRP HZ2  H  N N 351 
TRP HZ3  H  N N 352 
TRP HH2  H  N N 353 
TRP HXT  H  N N 354 
TYR N    N  N N 355 
TYR CA   C  N S 356 
TYR C    C  N N 357 
TYR O    O  N N 358 
TYR CB   C  N N 359 
TYR CG   C  Y N 360 
TYR CD1  C  Y N 361 
TYR CD2  C  Y N 362 
TYR CE1  C  Y N 363 
TYR CE2  C  Y N 364 
TYR CZ   C  Y N 365 
TYR OH   O  N N 366 
TYR OXT  O  N N 367 
TYR H    H  N N 368 
TYR H2   H  N N 369 
TYR HA   H  N N 370 
TYR HB2  H  N N 371 
TYR HB3  H  N N 372 
TYR HD1  H  N N 373 
TYR HD2  H  N N 374 
TYR HE1  H  N N 375 
TYR HE2  H  N N 376 
TYR HH   H  N N 377 
TYR HXT  H  N N 378 
VAL N    N  N N 379 
VAL CA   C  N S 380 
VAL C    C  N N 381 
VAL O    O  N N 382 
VAL CB   C  N N 383 
VAL CG1  C  N N 384 
VAL CG2  C  N N 385 
VAL OXT  O  N N 386 
VAL H    H  N N 387 
VAL H2   H  N N 388 
VAL HA   H  N N 389 
VAL HB   H  N N 390 
VAL HG11 H  N N 391 
VAL HG12 H  N N 392 
VAL HG13 H  N N 393 
VAL HG21 H  N N 394 
VAL HG22 H  N N 395 
VAL HG23 H  N N 396 
VAL HXT  H  N N 397 
XQN C11  C  Y N 398 
XQN C14  C  Y N 399 
XQN O15  O  N N 400 
XQN C17  C  Y N 401 
XQN B2   B  N N 402 
XQN C10  C  Y N 403 
XQN C13  C  Y N 404 
XQN C18  C  Y N 405 
XQN C19  C  Y N 406 
XQN C20  C  Y N 407 
XQN C21  C  Y N 408 
XQN C22  C  Y N 409 
XQN C4   C  N S 410 
XQN C5   C  N N 411 
XQN C8   C  Y N 412 
XQN C9   C  Y N 413 
XQN N6   N  N N 414 
XQN O1   O  N N 415 
XQN O16  O  N N 416 
XQN O3   O  N N 417 
XQN S7   S  N N 418 
XQN CL12 CL N N 419 
XQN H14  H  N N 420 
XQN H10  H  N N 421 
XQN H13  H  N N 422 
XQN H18  H  N N 423 
XQN H19  H  N N 424 
XQN H20  H  N N 425 
XQN H21  H  N N 426 
XQN H4   H  N N 427 
XQN H5B  H  N N 428 
XQN H5A  H  N N 429 
XQN H9   H  N N 430 
XQN H6   H  N N 431 
XQN H1   H  N N 432 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
SO4 S   O1   doub N N 290 
SO4 S   O2   doub N N 291 
SO4 S   O3   sing N N 292 
SO4 S   O4   sing N N 293 
THR N   CA   sing N N 294 
THR N   H    sing N N 295 
THR N   H2   sing N N 296 
THR CA  C    sing N N 297 
THR CA  CB   sing N N 298 
THR CA  HA   sing N N 299 
THR C   O    doub N N 300 
THR C   OXT  sing N N 301 
THR CB  OG1  sing N N 302 
THR CB  CG2  sing N N 303 
THR CB  HB   sing N N 304 
THR OG1 HG1  sing N N 305 
THR CG2 HG21 sing N N 306 
THR CG2 HG22 sing N N 307 
THR CG2 HG23 sing N N 308 
THR OXT HXT  sing N N 309 
TRP N   CA   sing N N 310 
TRP N   H    sing N N 311 
TRP N   H2   sing N N 312 
TRP CA  C    sing N N 313 
TRP CA  CB   sing N N 314 
TRP CA  HA   sing N N 315 
TRP C   O    doub N N 316 
TRP C   OXT  sing N N 317 
TRP CB  CG   sing N N 318 
TRP CB  HB2  sing N N 319 
TRP CB  HB3  sing N N 320 
TRP CG  CD1  doub Y N 321 
TRP CG  CD2  sing Y N 322 
TRP CD1 NE1  sing Y N 323 
TRP CD1 HD1  sing N N 324 
TRP CD2 CE2  doub Y N 325 
TRP CD2 CE3  sing Y N 326 
TRP NE1 CE2  sing Y N 327 
TRP NE1 HE1  sing N N 328 
TRP CE2 CZ2  sing Y N 329 
TRP CE3 CZ3  doub Y N 330 
TRP CE3 HE3  sing N N 331 
TRP CZ2 CH2  doub Y N 332 
TRP CZ2 HZ2  sing N N 333 
TRP CZ3 CH2  sing Y N 334 
TRP CZ3 HZ3  sing N N 335 
TRP CH2 HH2  sing N N 336 
TRP OXT HXT  sing N N 337 
TYR N   CA   sing N N 338 
TYR N   H    sing N N 339 
TYR N   H2   sing N N 340 
TYR CA  C    sing N N 341 
TYR CA  CB   sing N N 342 
TYR CA  HA   sing N N 343 
TYR C   O    doub N N 344 
TYR C   OXT  sing N N 345 
TYR CB  CG   sing N N 346 
TYR CB  HB2  sing N N 347 
TYR CB  HB3  sing N N 348 
TYR CG  CD1  doub Y N 349 
TYR CG  CD2  sing Y N 350 
TYR CD1 CE1  sing Y N 351 
TYR CD1 HD1  sing N N 352 
TYR CD2 CE2  doub Y N 353 
TYR CD2 HD2  sing N N 354 
TYR CE1 CZ   doub Y N 355 
TYR CE1 HE1  sing N N 356 
TYR CE2 CZ   sing Y N 357 
TYR CE2 HE2  sing N N 358 
TYR CZ  OH   sing N N 359 
TYR OH  HH   sing N N 360 
TYR OXT HXT  sing N N 361 
VAL N   CA   sing N N 362 
VAL N   H    sing N N 363 
VAL N   H2   sing N N 364 
VAL CA  C    sing N N 365 
VAL CA  CB   sing N N 366 
VAL CA  HA   sing N N 367 
VAL C   O    doub N N 368 
VAL C   OXT  sing N N 369 
VAL CB  CG1  sing N N 370 
VAL CB  CG2  sing N N 371 
VAL CB  HB   sing N N 372 
VAL CG1 HG11 sing N N 373 
VAL CG1 HG12 sing N N 374 
VAL CG1 HG13 sing N N 375 
VAL CG2 HG21 sing N N 376 
VAL CG2 HG22 sing N N 377 
VAL CG2 HG23 sing N N 378 
VAL OXT HXT  sing N N 379 
XQN O1  B2   sing N N 380 
XQN B2  O3   sing N N 381 
XQN O3  C4   sing N N 382 
XQN C4  C5   sing N N 383 
XQN C5  N6   sing N N 384 
XQN N6  S7   sing N N 385 
XQN S7  C8   sing N N 386 
XQN C8  C9   doub Y N 387 
XQN C9  C10  sing Y N 388 
XQN C10 C11  doub Y N 389 
XQN C11 CL12 sing N N 390 
XQN C11 C13  sing Y N 391 
XQN C13 C14  doub Y N 392 
XQN S7  O15  doub N N 393 
XQN S7  O16  doub N N 394 
XQN C4  C17  sing N N 395 
XQN C17 C18  doub Y N 396 
XQN C18 C19  sing Y N 397 
XQN C19 C20  doub Y N 398 
XQN C20 C21  sing Y N 399 
XQN C21 C22  doub Y N 400 
XQN C22 B2   sing N N 401 
XQN C14 C8   sing Y N 402 
XQN C22 C17  sing Y N 403 
XQN C14 H14  sing N N 404 
XQN C10 H10  sing N N 405 
XQN C13 H13  sing N N 406 
XQN C18 H18  sing N N 407 
XQN C19 H19  sing N N 408 
XQN C20 H20  sing N N 409 
XQN C21 H21  sing N N 410 
XQN C4  H4   sing N N 411 
XQN C5  H5B  sing N N 412 
XQN C5  H5A  sing N N 413 
XQN C9  H9   sing N N 414 
XQN N6  H6   sing N N 415 
XQN O1  H1   sing N N 416 
# 
_pdbx_audit_support.funding_organization   'Medical Research Council (MRC, United Kingdom)' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           MR/T016035/1 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6qw8 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8R31 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.022477 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.021939 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008500 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
B  ? ? 2.74417 2.23879 ? ? 37.84921 1.85376  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
C  ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CL ? ? 9.50761 7.44341 ? ? 1.04373  23.83732 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
NA ? ? 9.38062 1.54875 ? ? 3.38349  72.32734 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . THR A 1 4   ? 5.47855   -32.42228 8.01535  1.000 71.24783 ? 27  THR A N    1 
ATOM   2    C  CA   . THR A 1 4   ? 5.79381   -32.66174 6.61409  1.000 62.29945 ? 27  THR A CA   1 
ATOM   3    C  C    . THR A 1 4   ? 6.87050   -31.67958 6.14788  1.000 59.12635 ? 27  THR A C    1 
ATOM   4    O  O    . THR A 1 4   ? 6.81148   -30.47351 6.40310  1.000 59.54532 ? 27  THR A O    1 
ATOM   5    C  CB   . THR A 1 4   ? 4.54116   -32.53393 5.72496  1.000 62.54246 ? 27  THR A CB   1 
ATOM   6    O  OG1  . THR A 1 4   ? 3.48493   -33.34874 6.27020  1.000 82.28779 ? 27  THR A OG1  1 
ATOM   7    C  CG2  . THR A 1 4   ? 4.83670   -32.99665 4.31509  1.000 66.20049 ? 27  THR A CG2  1 
ATOM   8    H  HA   . THR A 1 4   ? 6.13477   -33.56236 6.49773  1.000 74.73925 ? 27  THR A HA   1 
ATOM   9    H  HB   . THR A 1 4   ? 4.26235   -31.60542 5.69279  1.000 75.03088 ? 27  THR A HB   1 
ATOM   10   H  HG1  . THR A 1 4   ? 3.03364   -32.90324 6.82108  1.000 98.72527 ? 27  THR A HG1  1 
ATOM   11   H  HG21 . THR A 1 4   ? 4.14253   -33.60286 4.01251  1.000 79.42051 ? 27  THR A HG21 1 
ATOM   12   H  HG22 . THR A 1 4   ? 4.87192   -32.23438 3.71626  1.000 79.42051 ? 27  THR A HG22 1 
ATOM   13   H  HG23 . THR A 1 4   ? 5.69004   -33.45711 4.28906  1.000 79.42051 ? 27  THR A HG23 1 
ATOM   14   N  N    . ALA A 1 5   ? 7.89830   -32.21084 5.49905  1.000 66.37136 ? 28  ALA A N    1 
ATOM   15   C  CA   . ALA A 1 5   ? 8.86962   -31.32155 4.88647  1.000 64.70146 ? 28  ALA A CA   1 
ATOM   16   C  C    . ALA A 1 5   ? 8.27299   -30.64282 3.66837  1.000 59.08795 ? 28  ALA A C    1 
ATOM   17   O  O    . ALA A 1 5   ? 8.71234   -29.55357 3.28754  1.000 60.86671 ? 28  ALA A O    1 
ATOM   18   C  CB   . ALA A 1 5   ? 10.13401  -32.09080 4.50345  1.000 62.68024 ? 28  ALA A CB   1 
ATOM   19   H  H    . ALA A 1 5   ? 8.05002   -33.05188 5.40296  1.000 79.62555 ? 28  ALA A H    1 
ATOM   20   H  HA   . ALA A 1 5   ? 9.13061   -30.64209 5.52766  1.000 77.62168 ? 28  ALA A HA   1 
ATOM   21   H  HB1  . ALA A 1 5   ? 10.80948  -31.46073 4.20737  1.000 75.19620 ? 28  ALA A HB1  1 
ATOM   22   H  HB2  . ALA A 1 5   ? 10.45379  -32.57867 5.27845  1.000 75.19620 ? 28  ALA A HB2  1 
ATOM   23   H  HB3  . ALA A 1 5   ? 9.92233   -32.70970 3.78718  1.000 75.19620 ? 28  ALA A HB3  1 
ATOM   24   N  N    . ASP A 1 6   ? 7.27307   -31.27028 3.04675  1.000 51.90215 ? 29  ASP A N    1 
ATOM   25   C  CA   . ASP A 1 6   ? 6.63680   -30.65021 1.89317  1.000 52.78670 ? 29  ASP A CA   1 
ATOM   26   C  C    . ASP A 1 6   ? 5.90378   -29.37727 2.29156  1.000 44.11143 ? 29  ASP A C    1 
ATOM   27   O  O    . ASP A 1 6   ? 5.99385   -28.36200 1.59203  1.000 38.99938 ? 29  ASP A O    1 
ATOM   28   C  CB   . ASP A 1 6   ? 5.67766   -31.62606 1.21968  1.000 50.25960 ? 29  ASP A CB   1 
ATOM   29   C  CG   . ASP A 1 6   ? 5.42977   -31.27599 -0.24056 1.000 63.75328 ? 29  ASP A CG   1 
ATOM   30   O  OD1  . ASP A 1 6   ? 6.19745   -30.46545 -0.80634 1.000 76.92176 ? 29  ASP A OD1  1 
ATOM   31   O  OD2  . ASP A 1 6   ? 4.46196   -31.80424 -0.82251 1.000 73.57339 ? 29  ASP A OD2  1 
ATOM   32   H  H    . ASP A 1 6   ? 6.95397   -32.03712 3.26973  1.000 62.26250 ? 29  ASP A H    1 
ATOM   33   H  HA   . ASP A 1 6   ? 7.32504   -30.42084 1.24925  1.000 63.32395 ? 29  ASP A HA   1 
ATOM   34   H  HB2  . ASP A 1 6   ? 6.05480   -32.51898 1.25636  1.000 60.29144 ? 29  ASP A HB2  1 
ATOM   35   H  HB3  . ASP A 1 6   ? 4.82610   -31.60627 1.68375  1.000 60.29144 ? 29  ASP A HB3  1 
ATOM   36   N  N    A VAL A 1 7   ? 5.16906   -29.39654 3.40615  0.284 37.73312 ? 30  VAL A N    1 
ATOM   37   N  N    B VAL A 1 7   ? 5.17222   -29.40874 3.40872  0.716 37.48856 ? 30  VAL A N    1 
ATOM   38   C  CA   A VAL A 1 7   ? 4.48768   -28.17407 3.82843  0.284 33.91383 ? 30  VAL A CA   1 
ATOM   39   C  CA   B VAL A 1 7   ? 4.49111   -28.19816 3.86430  0.716 33.85213 ? 30  VAL A CA   1 
ATOM   40   C  C    A VAL A 1 7   ? 5.50616   -27.07139 4.08680  0.284 33.41914 ? 30  VAL A C    1 
ATOM   41   C  C    B VAL A 1 7   ? 5.50344   -27.08372 4.08813  0.716 33.37721 ? 30  VAL A C    1 
ATOM   42   O  O    A VAL A 1 7   ? 5.26826   -25.89522 3.77731  0.284 28.17210 ? 30  VAL A O    1 
ATOM   43   O  O    B VAL A 1 7   ? 5.26354   -25.91545 3.74525  0.716 27.81628 ? 30  VAL A O    1 
ATOM   44   C  CB   A VAL A 1 7   ? 3.61163   -28.43843 5.06656  0.284 31.94496 ? 30  VAL A CB   1 
ATOM   45   C  CB   B VAL A 1 7   ? 3.67670   -28.49002 5.13967  0.716 31.75493 ? 30  VAL A CB   1 
ATOM   46   C  CG1  A VAL A 1 7   ? 4.46137   -28.89805 6.23097  0.284 36.38246 ? 30  VAL A CG1  1 
ATOM   47   C  CG1  B VAL A 1 7   ? 3.10916   -27.20640 5.70964  0.716 33.51711 ? 30  VAL A CG1  1 
ATOM   48   C  CG2  A VAL A 1 7   ? 2.82202   -27.18416 5.43377  0.284 32.56426 ? 30  VAL A CG2  1 
ATOM   49   C  CG2  B VAL A 1 7   ? 2.54456   -29.46386 4.84107  0.716 40.14524 ? 30  VAL A CG2  1 
ATOM   50   H  H    A VAL A 1 7   ? 5.05367   -30.07926 3.91622  0.284 45.25967 ? 30  VAL A H    1 
ATOM   51   H  H    B VAL A 1 7   ? 5.05786   -30.10024 3.90707  0.716 44.96619 ? 30  VAL A H    1 
ATOM   52   H  HA   A VAL A 1 7   ? 3.90109   -27.88569 3.11174  0.284 40.67651 ? 30  VAL A HA   1 
ATOM   53   H  HA   B VAL A 1 7   ? 3.87116   -27.91064 3.17590  0.716 40.60247 ? 30  VAL A HA   1 
ATOM   54   H  HB   A VAL A 1 7   ? 2.97971   -29.14519 4.86144  0.284 38.31387 ? 30  VAL A HB   1 
ATOM   55   H  HB   B VAL A 1 7   ? 4.26653   -28.89123 5.79697  0.716 38.08584 ? 30  VAL A HB   1 
ATOM   56   H  HG11 A VAL A 1 7   ? 3.88866   -29.05158 6.99865  0.284 43.63887 ? 30  VAL A HG11 1 
ATOM   57   H  HG11 B VAL A 1 7   ? 2.38415   -27.42365 6.31632  0.716 40.20045 ? 30  VAL A HG11 1 
ATOM   58   H  HG12 A VAL A 1 7   ? 4.91412   -29.72029 5.98635  0.284 43.63887 ? 30  VAL A HG12 1 
ATOM   59   H  HG12 B VAL A 1 7   ? 3.81020   -26.73577 6.18709  0.716 40.20045 ? 30  VAL A HG12 1 
ATOM   60   H  HG13 A VAL A 1 7   ? 5.11341   -28.21010 6.43703  0.284 43.63887 ? 30  VAL A HG13 1 
ATOM   61   H  HG13 B VAL A 1 7   ? 2.77819   -26.65695 4.98200  0.716 40.20045 ? 30  VAL A HG13 1 
ATOM   62   H  HG21 A VAL A 1 7   ? 2.20500   -27.39813 6.15100  0.284 39.05703 ? 30  VAL A HG21 1 
ATOM   63   H  HG21 B VAL A 1 7   ? 2.07148   -29.66030 5.66479  0.716 48.15421 ? 30  VAL A HG21 1 
ATOM   64   H  HG22 A VAL A 1 7   ? 3.44035   -26.49537 5.72383  0.284 39.05703 ? 30  VAL A HG22 1 
ATOM   65   H  HG22 B VAL A 1 7   ? 1.93944   -29.05791 4.20082  0.716 48.15421 ? 30  VAL A HG22 1 
ATOM   66   H  HG23 A VAL A 1 7   ? 2.33078   -26.88076 4.65432  0.284 39.05703 ? 30  VAL A HG23 1 
ATOM   67   H  HG23 B VAL A 1 7   ? 2.91847   -30.27920 4.47186  0.716 48.15421 ? 30  VAL A HG23 1 
ATOM   68   N  N    . GLN A 1 8   ? 6.65730   -27.43333 4.66073  1.000 39.14052 ? 31  GLN A N    1 
ATOM   69   C  CA   . GLN A 1 8   ? 7.72250   -26.46401 4.85887  1.000 38.98647 ? 31  GLN A CA   1 
ATOM   70   C  C    . GLN A 1 8   ? 8.14028   -25.85660 3.53446  1.000 33.61689 ? 31  GLN A C    1 
ATOM   71   O  O    . GLN A 1 8   ? 8.25125   -24.63479 3.39940  1.000 35.74162 ? 31  GLN A O    1 
ATOM   72   C  CB   . GLN A 1 8   ? 8.91607   -27.14885 5.52021  1.000 48.74325 ? 31  GLN A CB   1 
ATOM   73   C  CG   . GLN A 1 8   ? 8.66315   -27.50113 6.95251  1.000 52.98196 ? 31  GLN A CG   1 
ATOM   74   C  CD   . GLN A 1 8   ? 8.41920   -26.26124 7.76690  1.000 47.30748 ? 31  GLN A CD   1 
ATOM   75   O  OE1  . GLN A 1 8   ? 9.03420   -25.22559 7.52681  1.000 40.83835 ? 31  GLN A OE1  1 
ATOM   76   N  NE2  . GLN A 1 8   ? 7.50743   -26.34511 8.71037  1.000 44.27801 ? 31  GLN A NE2  1 
ATOM   77   H  H    A GLN A 1 8   ? 6.83970   -28.22621 4.93944  0.284 46.94855 ? 31  GLN A H    1 
ATOM   78   H  H    B GLN A 1 8   ? 6.84396   -28.22457 4.94127  0.716 46.94855 ? 31  GLN A H    1 
ATOM   79   H  HA   . GLN A 1 8   ? 7.40810   -25.75492 5.44132  1.000 46.76369 ? 31  GLN A HA   1 
ATOM   80   H  HB2  . GLN A 1 8   ? 9.11532   -27.96799 5.04041  1.000 58.47182 ? 31  GLN A HB2  1 
ATOM   81   H  HB3  . GLN A 1 8   ? 9.67975   -26.55162 5.48844  1.000 58.47182 ? 31  GLN A HB3  1 
ATOM   82   H  HG2  . GLN A 1 8   ? 7.87972   -28.06985 7.01320  1.000 63.55827 ? 31  GLN A HG2  1 
ATOM   83   H  HG3  . GLN A 1 8   ? 9.43625   -27.96162 7.31468  1.000 63.55827 ? 31  GLN A HG3  1 
ATOM   84   H  HE21 . GLN A 1 8   ? 7.08515   -27.08371 8.83583  1.000 53.11353 ? 31  GLN A HE21 1 
ATOM   85   H  HE22 . GLN A 1 8   ? 7.33330   -25.66136 9.20207  1.000 53.11353 ? 31  GLN A HE22 1 
ATOM   86   N  N    . GLN A 1 9   ? 8.42356   -26.71089 2.55540  1.000 37.68505 ? 32  GLN A N    1 
ATOM   87   C  CA   . GLN A 1 9   ? 8.85083   -26.21598 1.25821  1.000 42.62039 ? 32  GLN A CA   1 
ATOM   88   C  C    . GLN A 1 9   ? 7.77815   -25.33265 0.64178  1.000 32.34231 ? 32  GLN A C    1 
ATOM   89   O  O    . GLN A 1 9   ? 8.08474   -24.30115 0.03831  1.000 32.43533 ? 32  GLN A O    1 
ATOM   90   C  CB   . GLN A 1 9   ? 9.17805   -27.38945 0.34178  1.000 44.81509 ? 32  GLN A CB   1 
ATOM   91   C  CG   . GLN A 1 9   ? 9.44456   -26.95882 -1.08441 1.000 48.07280 ? 32  GLN A CG   1 
ATOM   92   C  CD   . GLN A 1 9   ? 10.07859  -28.05170 -1.92029 1.000 64.14844 ? 32  GLN A CD   1 
ATOM   93   O  OE1  . GLN A 1 9   ? 10.48022  -29.09573 -1.39990 1.000 76.56223 ? 32  GLN A OE1  1 
ATOM   94   N  NE2  . GLN A 1 9   ? 10.17446  -27.81527 -3.22694 1.000 54.52111 ? 32  GLN A NE2  1 
ATOM   95   H  H    . GLN A 1 9   ? 8.37650   -27.56734 2.61757  1.000 45.20198 ? 32  GLN A H    1 
ATOM   96   H  HA   . GLN A 1 9   ? 9.65620   -25.68564 1.36321  1.000 51.12439 ? 32  GLN A HA   1 
ATOM   97   H  HB2  . GLN A 1 9   ? 9.97141   -27.83806 0.67378  1.000 53.75803 ? 32  GLN A HB2  1 
ATOM   98   H  HB3  . GLN A 1 9   ? 8.42766   -28.00408 0.33516  1.000 53.75803 ? 32  GLN A HB3  1 
ATOM   99   H  HG2  . GLN A 1 9   ? 8.60456   -26.71170 -1.50180 1.000 57.66727 ? 32  GLN A HG2  1 
ATOM   100  H  HG3  . GLN A 1 9   ? 10.04766  -26.19913 -1.07736 1.000 57.66727 ? 32  GLN A HG3  1 
ATOM   101  H  HE21 . GLN A 1 9   ? 9.88418   -27.07397 -3.55222 1.000 65.40525 ? 32  GLN A HE21 1 
ATOM   102  H  HE22 . GLN A 1 9   ? 10.52667  -28.40384 -3.74572 1.000 65.40525 ? 32  GLN A HE22 1 
ATOM   103  N  N    . LYS A 1 10  ? 6.50783   -25.71581 0.79303  1.000 30.99053 ? 33  LYS A N    1 
ATOM   104  C  CA   . LYS A 1 10  ? 5.44429   -24.91861 0.20011  1.000 29.54887 ? 33  LYS A CA   1 
ATOM   105  C  C    . LYS A 1 10  ? 5.37228   -23.55275 0.86602  1.000 28.38789 ? 33  LYS A C    1 
ATOM   106  O  O    . LYS A 1 10  ? 5.19021   -22.54055 0.19735  1.000 23.63749 ? 33  LYS A O    1 
ATOM   107  C  CB   . LYS A 1 10  ? 4.10028   -25.64340 0.30099  1.000 28.90424 ? 33  LYS A CB   1 
ATOM   108  C  CG   . LYS A 1 10  ? 3.86988   -26.78116 -0.70433 1.000 33.82571 ? 33  LYS A CG   1 
ATOM   109  C  CD   . LYS A 1 10  ? 2.43073   -27.32518 -0.57698 1.000 55.01913 ? 33  LYS A CD   1 
ATOM   110  C  CE   . LYS A 1 10  ? 1.95905   -28.08623 -1.81500 1.000 56.18111 ? 33  LYS A CE   1 
ATOM   111  N  NZ   . LYS A 1 10  ? 2.67837   -29.37160 -1.99946 1.000 68.18754 ? 33  LYS A NZ   1 
ATOM   112  H  H    . LYS A 1 10  ? 6.24655   -26.41357 1.22251  1.000 37.16855 ? 33  LYS A H    1 
ATOM   113  H  HA   . LYS A 1 10  ? 5.63119   -24.79639 -0.74383 1.000 35.43857 ? 33  LYS A HA   1 
ATOM   114  H  HB2  . LYS A 1 10  ? 4.02922   -26.02731 1.18894  1.000 34.66501 ? 33  LYS A HB2  1 
ATOM   115  H  HB3  . LYS A 1 10  ? 3.39426   -24.99261 0.16345  1.000 34.66501 ? 33  LYS A HB3  1 
ATOM   116  H  HG2  . LYS A 1 10  ? 3.99697   -26.44923 -1.60686 1.000 40.57077 ? 33  LYS A HG2  1 
ATOM   117  H  HG3  . LYS A 1 10  ? 4.49141   -27.50425 -0.52618 1.000 40.57077 ? 33  LYS A HG3  1 
ATOM   118  H  HD2  . LYS A 1 10  ? 2.39008   -27.93246 0.17830  1.000 66.00288 ? 33  LYS A HD2  1 
ATOM   119  H  HD3  . LYS A 1 10  ? 1.82468   -26.58083 -0.43718 1.000 66.00288 ? 33  LYS A HD3  1 
ATOM   120  H  HE2  . LYS A 1 10  ? 1.01291   -28.28091 -1.72652 1.000 67.39725 ? 33  LYS A HE2  1 
ATOM   121  H  HE3  . LYS A 1 10  ? 2.11316   -27.53965 -2.60139 1.000 67.39725 ? 33  LYS A HE3  1 
ATOM   122  H  HZ1  . LYS A 1 10  ? 3.55096   -29.22181 -2.09019 1.000 81.80497 ? 33  LYS A HZ1  1 
ATOM   123  H  HZ2  . LYS A 1 10  ? 2.54747   -29.89769 -1.29362 1.000 81.80497 ? 33  LYS A HZ2  1 
ATOM   124  H  HZ3  . LYS A 1 10  ? 2.37916   -29.78604 -2.72803 1.000 81.80497 ? 33  LYS A HZ3  1 
ATOM   125  N  N    . LEU A 1 11  ? 5.51924   -23.48656 2.18418  1.000 23.69485 ? 34  LEU A N    1 
ATOM   126  C  CA   . LEU A 1 11  ? 5.48650   -22.17939 2.82133  1.000 24.44665 ? 34  LEU A CA   1 
ATOM   127  C  C    . LEU A 1 11  ? 6.68843   -21.33441 2.40335  1.000 19.98609 ? 34  LEU A C    1 
ATOM   128  O  O    . LEU A 1 11  ? 6.57322   -20.10862 2.26854  1.000 21.58531 ? 34  LEU A O    1 
ATOM   129  C  CB   . LEU A 1 11  ? 5.44136   -22.34306 4.33973  1.000 21.54572 ? 34  LEU A CB   1 
ATOM   130  C  CG   . LEU A 1 11  ? 4.14451   -22.90035 4.91904  1.000 23.46040 ? 34  LEU A CG   1 
ATOM   131  C  CD1  . LEU A 1 11  ? 4.36609   -23.13592 6.43688  1.000 25.31158 ? 34  LEU A CD1  1 
ATOM   132  C  CD2  . LEU A 1 11  ? 2.93536   -21.99780 4.64214  1.000 22.02410 ? 34  LEU A CD2  1 
ATOM   133  H  H    . LEU A 1 11  ? 5.63463   -24.15660 2.71080  1.000 28.41374 ? 34  LEU A H    1 
ATOM   134  H  HA   . LEU A 1 11  ? 4.68212   -21.71218 2.54638  1.000 29.31590 ? 34  LEU A HA   1 
ATOM   135  H  HB2  . LEU A 1 11  ? 6.15399   -22.94781 4.59920  1.000 25.83478 ? 34  LEU A HB2  1 
ATOM   136  H  HB3  . LEU A 1 11  ? 5.58311   -21.47156 4.74135  1.000 25.83478 ? 34  LEU A HB3  1 
ATOM   137  H  HG   . LEU A 1 11  ? 3.92226   -23.74013 4.48745  1.000 28.13240 ? 34  LEU A HG   1 
ATOM   138  H  HD11 . LEU A 1 11  ? 3.55662   -23.50846 6.82012  1.000 30.35382 ? 34  LEU A HD11 1 
ATOM   139  H  HD12 . LEU A 1 11  ? 5.10362   -23.75459 6.55608  1.000 30.35382 ? 34  LEU A HD12 1 
ATOM   140  H  HD13 . LEU A 1 11  ? 4.57331   -22.28855 6.86103  1.000 30.35382 ? 34  LEU A HD13 1 
ATOM   141  H  HD21 . LEU A 1 11  ? 2.14972   -22.38595 5.05808  1.000 26.40884 ? 34  LEU A HD21 1 
ATOM   142  H  HD22 . LEU A 1 11  ? 3.10605   -21.11828 5.01392  1.000 26.40884 ? 34  LEU A HD22 1 
ATOM   143  H  HD23 . LEU A 1 11  ? 2.80355   -21.93176 3.68341  1.000 26.40884 ? 34  LEU A HD23 1 
ATOM   144  N  N    . ALA A 1 12  ? 7.86015   -21.96394 2.23982  1.000 22.72750 ? 35  ALA A N    1 
ATOM   145  C  CA   . ALA A 1 12  ? 9.01881   -21.21315 1.77211  1.000 25.89433 ? 35  ALA A CA   1 
ATOM   146  C  C    . ALA A 1 12  ? 8.77370   -20.64725 0.37851  1.000 28.65223 ? 35  ALA A C    1 
ATOM   147  O  O    . ALA A 1 12  ? 9.16024   -19.51247 0.08161  1.000 26.82107 ? 35  ALA A O    1 
ATOM   148  C  CB   . ALA A 1 12  ? 10.26482  -22.09780 1.77403  1.000 28.75596 ? 35  ALA A CB   1 
ATOM   149  H  H    . ALA A 1 12  ? 8.00112   -22.79903 2.38935  1.000 27.25292 ? 35  ALA A H    1 
ATOM   150  H  HA   . ALA A 1 12  ? 9.17736   -20.47543 2.38165  1.000 31.05312 ? 35  ALA A HA   1 
ATOM   151  H  HB1  . ALA A 1 12  ? 11.02601  -21.57181 1.48278  1.000 34.48707 ? 35  ALA A HB1  1 
ATOM   152  H  HB2  . ALA A 1 12  ? 10.41593  -22.42853 2.67330  1.000 34.48707 ? 35  ALA A HB2  1 
ATOM   153  H  HB3  . ALA A 1 12  ? 10.12503  -22.84152 1.16721  1.000 34.48707 ? 35  ALA A HB3  1 
ATOM   154  N  N    . GLU A 1 13  ? 8.15414   -21.43635 -0.49704 1.000 25.45802 ? 36  GLU A N    1 
ATOM   155  C  CA   . GLU A 1 13  ? 7.84943   -20.96287 -1.84410 1.000 27.33924 ? 36  GLU A CA   1 
ATOM   156  C  C    . GLU A 1 13  ? 6.83281   -19.82551 -1.81780 1.000 26.33133 ? 36  GLU A C    1 
ATOM   157  O  O    . GLU A 1 13  ? 6.97665   -18.83681 -2.55040 1.000 24.69319 ? 36  GLU A O    1 
ATOM   158  C  CB   . GLU A 1 13  ? 7.34180   -22.12929 -2.69698 1.000 28.71852 ? 36  GLU A CB   1 
ATOM   159  C  CG   . GLU A 1 13  ? 8.39639   -23.20812 -2.95330 1.000 41.78718 ? 36  GLU A CG   1 
ATOM   160  C  CD   . GLU A 1 13  ? 7.81132   -24.50327 -3.51337 1.000 44.38089 ? 36  GLU A CD   1 
ATOM   161  O  OE1  . GLU A 1 13  ? 6.57090   -24.66480 -3.48151 1.000 48.55424 ? 36  GLU A OE1  1 
ATOM   162  O  OE2  . GLU A 1 13  ? 8.59683   -25.36506 -3.97045 1.000 54.95338 ? 36  GLU A OE2  1 
ATOM   163  H  H    . GLU A 1 13  ? 7.90158   -22.24293 -0.33814 1.000 30.52955 ? 36  GLU A H    1 
ATOM   164  H  HA   . GLU A 1 13  ? 8.66081   -20.62106 -2.25121 1.000 32.78700 ? 36  GLU A HA   1 
ATOM   165  H  HB2  . GLU A 1 13  ? 6.59478   -22.54742 -2.24087 1.000 34.44215 ? 36  GLU A HB2  1 
ATOM   166  H  HB3  . GLU A 1 13  ? 7.05470   -21.78509 -3.55721 1.000 34.44215 ? 36  GLU A HB3  1 
ATOM   167  H  HG2  . GLU A 1 13  ? 9.04122   -22.87091 -3.59469 1.000 50.12454 ? 36  GLU A HG2  1 
ATOM   168  H  HG3  . GLU A 1 13  ? 8.83974   -23.41902 -2.11672 1.000 50.12454 ? 36  GLU A HG3  1 
ATOM   169  N  N    . LEU A 1 14  ? 5.80154   -19.94150 -0.98368 1.000 23.67831 ? 37  LEU A N    1 
ATOM   170  C  CA   . LEU A 1 14  ? 4.87926   -18.82673 -0.80743 1.000 25.38077 ? 37  LEU A CA   1 
ATOM   171  C  C    . LEU A 1 14  ? 5.60756   -17.57281 -0.34929 1.000 21.06851 ? 37  LEU A C    1 
ATOM   172  O  O    . LEU A 1 14  ? 5.38456   -16.47947 -0.89231 1.000 21.33515 ? 37  LEU A O    1 
ATOM   173  C  CB   . LEU A 1 14  ? 3.80330   -19.19567 0.20636  1.000 23.11432 ? 37  LEU A CB   1 
ATOM   174  C  CG   . LEU A 1 14  ? 2.83340   -18.08648 0.56844  1.000 21.97767 ? 37  LEU A CG   1 
ATOM   175  C  CD1  . LEU A 1 14  ? 2.05059   -17.66170 -0.67169 1.000 25.26289 ? 37  LEU A CD1  1 
ATOM   176  C  CD2  . LEU A 1 14  ? 1.90662   -18.59356 1.67133  1.000 20.01448 ? 37  LEU A CD2  1 
ATOM   177  H  H    . LEU A 1 14  ? 5.61805   -20.64081 -0.51796 1.000 28.39389 ? 37  LEU A H    1 
ATOM   178  H  HA   . LEU A 1 14  ? 4.45635   -18.64358 -1.66095 1.000 30.43684 ? 37  LEU A HA   1 
ATOM   179  H  HB2  . LEU A 1 14  ? 3.28151   -19.92796 -0.15750 1.000 27.71711 ? 37  LEU A HB2  1 
ATOM   180  H  HB3  . LEU A 1 14  ? 4.24100   -19.47518 1.02562  1.000 27.71711 ? 37  LEU A HB3  1 
ATOM   181  H  HG   . LEU A 1 14  ? 3.30200   -17.30287 0.89597  1.000 26.35312 ? 37  LEU A HG   1 
ATOM   182  H  HD11 . LEU A 1 14  ? 1.40172   -16.98621 -0.41953 1.000 30.29539 ? 37  LEU A HD11 1 
ATOM   183  H  HD12 . LEU A 1 14  ? 2.66806   -17.29927 -1.32611 1.000 30.29539 ? 37  LEU A HD12 1 
ATOM   184  H  HD13 . LEU A 1 14  ? 1.59625   -18.43604 -1.03893 1.000 30.29539 ? 37  LEU A HD13 1 
ATOM   185  H  HD21 . LEU A 1 14  ? 1.29892   -17.88148 1.92537  1.000 23.99729 ? 37  LEU A HD21 1 
ATOM   186  H  HD22 . LEU A 1 14  ? 1.40463   -19.35344 1.33743  1.000 23.99729 ? 37  LEU A HD22 1 
ATOM   187  H  HD23 . LEU A 1 14  ? 2.44140   -18.86033 2.43537  1.000 23.99729 ? 37  LEU A HD23 1 
ATOM   188  N  N    . GLU A 1 15  ? 6.44642   -17.70011 0.68408  1.000 23.72377 ? 38  GLU A N    1 
ATOM   189  C  CA   . GLU A 1 15  ? 7.13287   -16.52331 1.19464  1.000 20.72814 ? 38  GLU A CA   1 
ATOM   190  C  C    . GLU A 1 15  ? 7.98004   -15.88456 0.10514  1.000 24.39562 ? 38  GLU A C    1 
ATOM   191  O  O    . GLU A 1 15  ? 7.95215   -14.65920 -0.08668 1.000 20.28211 ? 38  GLU A O    1 
ATOM   192  C  CB   . GLU A 1 15  ? 7.98544   -16.88247 2.39479  1.000 20.89800 ? 38  GLU A CB   1 
ATOM   193  C  CG   . GLU A 1 15  ? 8.84066   -15.72408 2.86326  1.000 23.71411 ? 38  GLU A CG   1 
ATOM   194  C  CD   . GLU A 1 15  ? 9.72009   -16.07698 4.03526  1.000 23.13767 ? 38  GLU A CD   1 
ATOM   195  O  OE1  . GLU A 1 15  ? 10.68219  -16.85066 3.83167  1.000 23.32194 ? 38  GLU A OE1  1 
ATOM   196  O  OE2  . GLU A 1 15  ? 9.45260   -15.57455 5.16451  1.000 22.11776 ? 38  GLU A OE2  1 
ATOM   197  H  H    . GLU A 1 15  ? 6.62651   -18.43591 1.09123  1.000 28.44844 ? 38  GLU A H    1 
ATOM   198  H  HA   . GLU A 1 15  ? 6.47062   -15.87902 1.48994  1.000 24.85369 ? 38  GLU A HA   1 
ATOM   199  H  HB2  . GLU A 1 15  ? 7.40666   -17.14587 3.12728  1.000 25.05752 ? 38  GLU A HB2  1 
ATOM   200  H  HB3  . GLU A 1 15  ? 8.57439   -17.61566 2.15716  1.000 25.05752 ? 38  GLU A HB3  1 
ATOM   201  H  HG2  . GLU A 1 15  ? 9.41408   -15.44066 2.13404  1.000 28.43686 ? 38  GLU A HG2  1 
ATOM   202  H  HG3  . GLU A 1 15  ? 8.26182   -14.99401 3.13314  1.000 28.43686 ? 38  GLU A HG3  1 
ATOM   203  N  N    . ARG A 1 16  ? 8.74098   -16.71318 -0.62189 1.000 24.44666 ? 39  ARG A N    1 
ATOM   204  C  CA   . ARG A 1 16  ? 9.60956   -16.20920 -1.67816 1.000 24.79627 ? 39  ARG A CA   1 
ATOM   205  C  C    . ARG A 1 16  ? 8.81358   -15.43723 -2.71893 1.000 24.38379 ? 39  ARG A C    1 
ATOM   206  O  O    . ARG A 1 16  ? 9.19641   -14.33137 -3.11614 1.000 23.64397 ? 39  ARG A O    1 
ATOM   207  C  CB   . ARG A 1 16  ? 10.34841  -17.38153 -2.33165 1.000 24.80400 ? 39  ARG A CB   1 
ATOM   208  C  CG   . ARG A 1 16  ? 11.30788  -17.00758 -3.44125 1.000 25.49842 ? 39  ARG A CG   1 
ATOM   209  C  CD   . ARG A 1 16  ? 12.10443  -18.25775 -3.86531 1.000 29.24709 ? 39  ARG A CD   1 
ATOM   210  N  NE   . ARG A 1 16  ? 11.22734  -19.30063 -4.38072 1.000 29.73065 ? 39  ARG A NE   1 
ATOM   211  C  CZ   . ARG A 1 16  ? 11.61993  -20.51870 -4.74408 1.000 35.29790 ? 39  ARG A CZ   1 
ATOM   212  N  NH1  . ARG A 1 16  ? 12.88173  -20.90745 -4.63439 1.000 45.24923 ? 39  ARG A NH1  1 
ATOM   213  N  NH2  . ARG A 1 16  ? 10.72466  -21.36455 -5.24712 1.000 35.97490 ? 39  ARG A NH2  1 
ATOM   214  H  H    . ARG A 1 16  ? 8.76902   -17.56668 -0.52018 1.000 29.31591 ? 39  ARG A H    1 
ATOM   215  H  HA   . ARG A 1 16  ? 10.26343  -15.60593 -1.29161 1.000 29.73545 ? 39  ARG A HA   1 
ATOM   216  H  HB2  . ARG A 1 16  ? 10.86199  -17.83837 -1.64723 1.000 29.74472 ? 39  ARG A HB2  1 
ATOM   217  H  HB3  . ARG A 1 16  ? 9.68974   -17.98466 -2.71018 1.000 29.74472 ? 39  ARG A HB3  1 
ATOM   218  H  HG2  . ARG A 1 16  ? 10.81368  -16.67493 -4.20676 1.000 30.57803 ? 39  ARG A HG2  1 
ATOM   219  H  HG3  . ARG A 1 16  ? 11.92806  -16.33106 -3.12727 1.000 30.57803 ? 39  ARG A HG3  1 
ATOM   220  H  HD2  . ARG A 1 16  ? 12.73370  -18.01615 -4.56285 1.000 35.07643 ? 39  ARG A HD2  1 
ATOM   221  H  HD3  . ARG A 1 16  ? 12.58002  -18.61117 -3.09733 1.000 35.07643 ? 39  ARG A HD3  1 
ATOM   222  H  HE   . ARG A 1 16  ? 10.39111  -19.11443 -4.45588 1.000 35.65670 ? 39  ARG A HE   1 
ATOM   223  H  HH11 . ARG A 1 16  ? 13.47259  -20.36673 -4.32118 1.000 54.27900 ? 39  ARG A HH11 1 
ATOM   224  H  HH12 . ARG A 1 16  ? 13.10992  -21.70051 -4.87642 1.000 54.27900 ? 39  ARG A HH12 1 
ATOM   225  H  HH21 . ARG A 1 16  ? 9.90438   -21.12116 -5.33376 1.000 43.14981 ? 39  ARG A HH21 1 
ATOM   226  H  HH22 . ARG A 1 16  ? 10.96622  -22.15471 -5.48564 1.000 43.14981 ? 39  ARG A HH22 1 
ATOM   227  N  N    . GLN A 1 17  ? 7.72498   -16.02871 -3.20707 1.000 22.34457 ? 40  GLN A N    1 
ATOM   228  C  CA   . GLN A 1 17  ? 6.93230   -15.37110 -4.22933 1.000 28.87439 ? 40  GLN A CA   1 
ATOM   229  C  C    . GLN A 1 17  ? 6.27785   -14.09883 -3.69415 1.000 22.80000 ? 40  GLN A C    1 
ATOM   230  O  O    . GLN A 1 17  ? 6.09783   -13.14090 -4.45706 1.000 24.78200 ? 40  GLN A O    1 
ATOM   231  C  CB   . GLN A 1 17  ? 5.85660   -16.32553 -4.76298 1.000 26.57786 ? 40  GLN A CB   1 
ATOM   232  C  CG   . GLN A 1 17  ? 5.15256   -15.81944 -6.03077 1.000 29.29890 ? 40  GLN A CG   1 
ATOM   233  C  CD   . GLN A 1 17  ? 4.08927   -14.73731 -5.74623 1.000 53.29695 ? 40  GLN A CD   1 
ATOM   234  O  OE1  . GLN A 1 17  ? 3.55390   -14.63185 -4.63616 1.000 49.58806 ? 40  GLN A OE1  1 
ATOM   235  N  NE2  . GLN A 1 17  ? 3.79049   -13.92894 -6.76591 1.000 48.97107 ? 40  GLN A NE2  1 
ATOM   236  H  H    . GLN A 1 17  ? 7.43120   -16.79964 -2.96426 1.000 26.79340 ? 40  GLN A H    1 
ATOM   237  H  HA   . GLN A 1 17  ? 7.51522   -15.13114 -4.96657 1.000 34.62919 ? 40  GLN A HA   1 
ATOM   238  H  HB2  . GLN A 1 17  ? 6.27199   -17.17614 -4.97467 1.000 31.87335 ? 40  GLN A HB2  1 
ATOM   239  H  HB3  . GLN A 1 17  ? 5.18081   -16.44771 -4.07793 1.000 31.87335 ? 40  GLN A HB3  1 
ATOM   240  H  HG2  . GLN A 1 17  ? 5.81528   -15.43648 -6.62662 1.000 35.13860 ? 40  GLN A HG2  1 
ATOM   241  H  HG3  . GLN A 1 17  ? 4.70942   -16.56601 -6.46339 1.000 35.13860 ? 40  GLN A HG3  1 
ATOM   242  H  HE21 . GLN A 1 17  ? 4.18375   -14.02973 -7.52406 1.000 58.74520 ? 40  GLN A HE21 1 
ATOM   243  H  HE22 . GLN A 1 17  ? 3.20478   -13.30743 -6.66458 1.000 58.74520 ? 40  GLN A HE22 1 
ATOM   244  N  N    . SER A 1 18  ? 5.91156   -14.07883 -2.40477 1.000 21.36247 ? 41  SER A N    1 
ATOM   245  C  CA   . SER A 1 18  ? 5.20693   -12.92615 -1.84344 1.000 22.43253 ? 41  SER A CA   1 
ATOM   246  C  C    . SER A 1 18  ? 6.07915   -11.68516 -1.74704 1.000 24.63411 ? 41  SER A C    1 
ATOM   247  O  O    . SER A 1 18  ? 5.54805   -10.56400 -1.70875 1.000 22.56009 ? 41  SER A O    1 
ATOM   248  C  CB   . SER A 1 18  ? 4.67081   -13.27028 -0.45303 1.000 19.80498 ? 41  SER A CB   1 
ATOM   249  O  OG   . SER A 1 18  ? 5.75050   -13.28356 0.47479  1.000 19.73184 ? 41  SER A OG   1 
ATOM   250  H  H    A SER A 1 18  ? 6.05874   -14.71357 -1.84348 0.370 25.61488 ? 41  SER A H    1 
ATOM   251  H  H    B SER A 1 18  ? 6.05874   -14.71357 -1.84348 0.630 25.61488 ? 41  SER A H    1 
ATOM   252  H  HA   . SER A 1 18  ? 4.45952   -12.71924 -2.42607 1.000 26.89895 ? 41  SER A HA   1 
ATOM   253  H  HB2  . SER A 1 18  ? 4.02208   -12.60156 -0.18311 1.000 23.74590 ? 41  SER A HB2  1 
ATOM   254  H  HB3  . SER A 1 18  ? 4.25457   -14.14613 -0.47576 1.000 23.74590 ? 41  SER A HB3  1 
ATOM   255  H  HG   . SER A 1 18  ? 6.34303   -13.82093 0.21840  1.000 23.65813 ? 41  SER A HG   1 
ATOM   256  N  N    . GLY A 1 19  ? 7.39804   -11.85098 -1.68337 1.000 21.36768 ? 42  GLY A N    1 
ATOM   257  C  CA   . GLY A 1 19  ? 8.30318   -10.73419 -1.56331 1.000 22.70656 ? 42  GLY A CA   1 
ATOM   258  C  C    . GLY A 1 19  ? 8.53892   -10.27745 -0.14885 1.000 24.13098 ? 42  GLY A C    1 
ATOM   259  O  O    . GLY A 1 19  ? 9.39498   -9.39418  0.07839  1.000 22.08281 ? 42  GLY A O    1 
ATOM   260  H  H    . GLY A 1 19  ? 7.79014   -12.61597 -1.70884 1.000 25.62114 ? 42  GLY A H    1 
ATOM   261  H  HA2  . GLY A 1 19  ? 9.16020   -10.98397 -1.94282 1.000 27.22779 ? 42  GLY A HA2  1 
ATOM   262  H  HA3  . GLY A 1 19  ? 7.94308   -9.98462  -2.06267 1.000 27.22779 ? 42  GLY A HA3  1 
ATOM   263  N  N    . GLY A 1 20  ? 7.82385   -10.84800 0.80080  1.000 17.30310 ? 43  GLY A N    1 
ATOM   264  C  CA   . GLY A 1 20  ? 7.92968   -10.40308 2.17779  1.000 21.62814 ? 43  GLY A CA   1 
ATOM   265  C  C    . GLY A 1 20  ? 8.45266   -11.45654 3.12438  1.000 23.15135 ? 43  GLY A C    1 
ATOM   266  O  O    . GLY A 1 20  ? 9.19106   -12.36878 2.71358  1.000 20.56183 ? 43  GLY A O    1 
ATOM   267  H  H    . GLY A 1 20  ? 7.27022   -11.49409 0.67567  1.000 20.74364 ? 43  GLY A H    1 
ATOM   268  H  HA2  . GLY A 1 20  ? 8.52913   -9.64150  2.21719  1.000 25.93369 ? 43  GLY A HA2  1 
ATOM   269  H  HA3  . GLY A 1 20  ? 7.05218   -10.13070 2.48877  1.000 25.93369 ? 43  GLY A HA3  1 
ATOM   270  N  N    . ARG A 1 21  ? 8.07502   -11.31506 4.40456  1.000 19.07633 ? 44  ARG A N    1 
ATOM   271  C  CA   . ARG A 1 21  ? 8.48378   -12.18687 5.50067  1.000 15.91375 ? 44  ARG A CA   1 
ATOM   272  C  C    . ARG A 1 21  ? 7.23247   -12.77016 6.13492  1.000 16.05653 ? 44  ARG A C    1 
ATOM   273  O  O    . ARG A 1 21  ? 6.34811   -12.02646 6.57870  1.000 15.91399 ? 44  ARG A O    1 
ATOM   274  C  CB   . ARG A 1 21  ? 9.29727   -11.41619 6.54582  1.000 18.20039 ? 44  ARG A CB   1 
ATOM   275  C  CG   . ARG A 1 21  ? 9.78607   -12.27467 7.70211  1.000 18.68325 ? 44  ARG A CG   1 
ATOM   276  C  CD   . ARG A 1 21  ? 10.90312  -11.56126 8.47061  1.000 19.13985 ? 44  ARG A CD   1 
ATOM   277  N  NE   . ARG A 1 21  ? 10.34703  -10.42278 9.18760  1.000 20.86603 ? 44  ARG A NE   1 
ATOM   278  C  CZ   . ARG A 1 21  ? 9.87101   -10.47104 10.42354 1.000 19.93911 ? 44  ARG A CZ   1 
ATOM   279  N  NH1  . ARG A 1 21  ? 9.99184   -11.55471 11.17454 1.000 21.45339 ? 44  ARG A NH1  1 
ATOM   280  N  NH2  . ARG A 1 21  ? 9.30446   -9.37945  10.94530 1.000 22.00557 ? 44  ARG A NH2  1 
ATOM   281  H  H    . ARG A 1 21  ? 7.55362   -10.68477 4.67004  1.000 22.87151 ? 44  ARG A H    1 
ATOM   282  H  HA   . ARG A 1 21  ? 9.03230   -12.90917 5.15673  1.000 19.07642 ? 44  ARG A HA   1 
ATOM   283  H  HB2  . ARG A 1 21  ? 10.07589  -11.03236 6.11301  1.000 21.82039 ? 44  ARG A HB2  1 
ATOM   284  H  HB3  . ARG A 1 21  ? 8.74189   -10.71178 6.91494  1.000 21.82039 ? 44  ARG A HB3  1 
ATOM   285  H  HG2  . ARG A 1 21  ? 9.05190   -12.44512 8.31272  1.000 22.39981 ? 44  ARG A HG2  1 
ATOM   286  H  HG3  . ARG A 1 21  ? 10.13407  -13.11279 7.35955  1.000 22.39981 ? 44  ARG A HG3  1 
ATOM   287  H  HD2  . ARG A 1 21  ? 11.30283  -12.17045 9.11094  1.000 22.94774 ? 44  ARG A HD2  1 
ATOM   288  H  HD3  . ARG A 1 21  ? 11.57739  -11.24249 7.85041  1.000 22.94774 ? 44  ARG A HD3  1 
ATOM   289  H  HE   . ARG A 1 21  ? 10.32593  -9.66556  8.78045  1.000 25.01916 ? 44  ARG A HE   1 
ATOM   290  H  HH11 . ARG A 1 21  ? 10.38764  -12.25179 10.86307 1.000 25.72399 ? 44  ARG A HH11 1 
ATOM   291  H  HH12 . ARG A 1 21  ? 9.67451   -11.56153 11.97383 1.000 25.72399 ? 44  ARG A HH12 1 
ATOM   292  H  HH21 . ARG A 1 21  ? 9.25233   -8.65794  10.48021 1.000 26.38660 ? 44  ARG A HH21 1 
ATOM   293  H  HH22 . ARG A 1 21  ? 8.99188   -9.39827  11.74626 1.000 26.38660 ? 44  ARG A HH22 1 
ATOM   294  N  N    . LEU A 1 22  ? 7.16592   -14.10154 6.17900  1.000 19.19521 ? 45  LEU A N    1 
ATOM   295  C  CA   . LEU A 1 22  ? 5.97909   -14.83083 6.57828  1.000 17.32893 ? 45  LEU A CA   1 
ATOM   296  C  C    . LEU A 1 22  ? 6.23564   -15.61198 7.84411  1.000 18.00528 ? 45  LEU A C    1 
ATOM   297  O  O    . LEU A 1 22  ? 7.27429   -16.24701 7.97615  1.000 16.46156 ? 45  LEU A O    1 
ATOM   298  C  CB   . LEU A 1 22  ? 5.57993   -15.80203 5.47086  1.000 20.77018 ? 45  LEU A CB   1 
ATOM   299  C  CG   . LEU A 1 22  ? 4.44997   -16.78134 5.72886  1.000 17.78078 ? 45  LEU A CG   1 
ATOM   300  C  CD1  . LEU A 1 22  ? 3.12186   -16.03234 5.77661  1.000 17.99195 ? 45  LEU A CD1  1 
ATOM   301  C  CD2  . LEU A 1 22  ? 4.44590   -17.85124 4.62901  1.000 25.43585 ? 45  LEU A CD2  1 
ATOM   302  H  H    . LEU A 1 22  ? 7.82355   -14.61611 5.97321  1.000 23.01417 ? 45  LEU A H    1 
ATOM   303  H  HA   . LEU A 1 22  ? 5.25796   -14.20688 6.75588  1.000 20.77463 ? 45  LEU A HA   1 
ATOM   304  H  HB2  . LEU A 1 22  ? 5.31557   -15.27372 4.70150  1.000 24.90414 ? 45  LEU A HB2  1 
ATOM   305  H  HB3  . LEU A 1 22  ? 6.36136   -16.33459 5.25492  1.000 24.90414 ? 45  LEU A HB3  1 
ATOM   306  H  HG   . LEU A 1 22  ? 4.57050   -17.22531 6.58283  1.000 21.31686 ? 45  LEU A HG   1 
ATOM   307  H  HD11 . LEU A 1 22  ? 2.40676   -16.66747 5.93829  1.000 21.57026 ? 45  LEU A HD11 1 
ATOM   308  H  HD12 . LEU A 1 22  ? 3.15297   -15.37969 6.49353  1.000 21.57026 ? 45  LEU A HD12 1 
ATOM   309  H  HD13 . LEU A 1 22  ? 2.98105   -15.58471 4.92767  1.000 21.57026 ? 45  LEU A HD13 1 
ATOM   310  H  HD21 . LEU A 1 22  ? 3.68975   -18.44297 4.76685  1.000 30.50294 ? 45  LEU A HD21 1 
ATOM   311  H  HD22 . LEU A 1 22  ? 4.37217   -17.41598 3.76530  1.000 30.50294 ? 45  LEU A HD22 1 
ATOM   312  H  HD23 . LEU A 1 22  ? 5.27328   -18.35539 4.67580  1.000 30.50294 ? 45  LEU A HD23 1 
ATOM   313  N  N    . GLY A 1 23  ? 5.28250   -15.55711 8.77001  1.000 20.34403 ? 46  GLY A N    1 
ATOM   314  C  CA   . GLY A 1 23  ? 5.39824   -16.32385 9.98917  1.000 18.32293 ? 46  GLY A CA   1 
ATOM   315  C  C    . GLY A 1 23  ? 4.13847   -17.12582 10.21691 1.000 17.86359 ? 46  GLY A C    1 
ATOM   316  O  O    . GLY A 1 23  ? 3.03748   -16.59055 10.15408 1.000 15.49917 ? 46  GLY A O    1 
ATOM   317  H  H    . GLY A 1 23  ? 4.56652   -15.08452 8.70978  1.000 24.39276 ? 46  GLY A H    1 
ATOM   318  H  HA2  . GLY A 1 23  ? 6.15230   -16.93084 9.92704  1.000 21.96743 ? 46  GLY A HA2  1 
ATOM   319  H  HA3  . GLY A 1 23  ? 5.53385   -15.72782 10.74234 1.000 21.96743 ? 46  GLY A HA3  1 
ATOM   320  N  N    . VAL A 1 24  ? 4.28174   -18.41729 10.47185 1.000 16.44246 ? 47  VAL A N    1 
ATOM   321  C  CA   . VAL A 1 24  ? 3.13413   -19.31152 10.60644 1.000 17.10366 ? 47  VAL A CA   1 
ATOM   322  C  C    . VAL A 1 24  ? 3.35385   -20.20963 11.81563 1.000 17.03405 ? 47  VAL A C    1 
ATOM   323  O  O    . VAL A 1 24  ? 4.45306   -20.73229 12.03500 1.000 15.96062 ? 47  VAL A O    1 
ATOM   324  C  CB   . VAL A 1 24  ? 2.93618   -20.17929 9.33749  1.000 20.05260 ? 47  VAL A CB   1 
ATOM   325  C  CG1  . VAL A 1 24  ? 1.80094   -21.17077 9.53703  1.000 16.67421 ? 47  VAL A CG1  1 
ATOM   326  C  CG2  . VAL A 1 24  ? 2.67496   -19.33300 8.09293  1.000 18.68304 ? 47  VAL A CG2  1 
ATOM   327  H  H    . VAL A 1 24  ? 5.04160   -18.80717 10.57290 1.000 19.71087 ? 47  VAL A H    1 
ATOM   328  H  HA   . VAL A 1 24  ? 2.33744   -18.77769 10.75204 1.000 20.50431 ? 47  VAL A HA   1 
ATOM   329  H  HB   . VAL A 1 24  ? 3.76192   -20.66649 9.19018  1.000 24.04303 ? 47  VAL A HB   1 
ATOM   330  H  HG11 . VAL A 1 24  ? 1.55783   -21.54960 8.67780  1.000 19.98898 ? 47  VAL A HG11 1 
ATOM   331  H  HG12 . VAL A 1 24  ? 2.09711   -21.87350 10.13649 1.000 19.98898 ? 47  VAL A HG12 1 
ATOM   332  H  HG13 . VAL A 1 24  ? 1.04049   -20.70701 9.92115  1.000 19.98898 ? 47  VAL A HG13 1 
ATOM   333  H  HG21 . VAL A 1 24  ? 2.51024   -19.92155 7.33969  1.000 22.39957 ? 47  VAL A HG21 1 
ATOM   334  H  HG22 . VAL A 1 24  ? 1.89962   -18.77161 8.24980  1.000 22.39957 ? 47  VAL A HG22 1 
ATOM   335  H  HG23 . VAL A 1 24  ? 3.45299   -18.78094 7.91741  1.000 22.39957 ? 47  VAL A HG23 1 
ATOM   336  N  N    . ALA A 1 25  ? 2.30661   -20.38615 12.61691 1.000 16.41501 ? 48  ALA A N    1 
ATOM   337  C  CA   . ALA A 1 25  ? 2.29279   -21.43453 13.63618 1.000 15.42472 ? 48  ALA A CA   1 
ATOM   338  C  C    . ALA A 1 25  ? 0.92058   -22.07611 13.60987 1.000 16.35828 ? 48  ALA A C    1 
ATOM   339  O  O    . ALA A 1 25  ? -0.08501  -21.38078 13.81759 1.000 18.37057 ? 48  ALA A O    1 
ATOM   340  C  CB   . ALA A 1 25  ? 2.60965   -20.85934 15.03260 1.000 18.08527 ? 48  ALA A CB   1 
ATOM   341  H  H    . ALA A 1 25  ? 1.59033   -19.91093 12.59029 1.000 19.67793 ? 48  ALA A H    1 
ATOM   342  H  HA   . ALA A 1 25  ? 2.95995   -22.10984 13.43678 1.000 18.48959 ? 48  ALA A HA   1 
ATOM   343  H  HB1  . ALA A 1 25  ? 2.59496   -21.57996 15.68174 1.000 21.68224 ? 48  ALA A HB1  1 
ATOM   344  H  HB2  . ALA A 1 25  ? 3.48856   -20.44940 15.01329 1.000 21.68224 ? 48  ALA A HB2  1 
ATOM   345  H  HB3  . ALA A 1 25  ? 1.93997   -20.19551 15.26010 1.000 21.68224 ? 48  ALA A HB3  1 
ATOM   346  N  N    . LEU A 1 26  ? 0.86614   -23.37937 13.29206 1.000 18.69109 ? 49  LEU A N    1 
ATOM   347  C  CA   . LEU A 1 26  ? -0.35060  -24.18001 13.37482 1.000 17.33718 ? 49  LEU A CA   1 
ATOM   348  C  C    . LEU A 1 26  ? -0.20549  -25.15458 14.53953 1.000 19.89662 ? 49  LEU A C    1 
ATOM   349  O  O    . LEU A 1 26  ? 0.80244   -25.86942 14.62604 1.000 21.50348 ? 49  LEU A O    1 
ATOM   350  C  CB   . LEU A 1 26  ? -0.61346  -24.97999 12.09160 1.000 19.38741 ? 49  LEU A CB   1 
ATOM   351  C  CG   . LEU A 1 26  ? -1.79352  -25.96551 12.19459 1.000 19.34461 ? 49  LEU A CG   1 
ATOM   352  C  CD1  . LEU A 1 26  ? -3.09349  -25.23928 12.06386 1.000 21.50951 ? 49  LEU A CD1  1 
ATOM   353  C  CD2  . LEU A 1 26  ? -1.68972  -27.06956 11.13729 1.000 28.23822 ? 49  LEU A CD2  1 
ATOM   354  H  H    . LEU A 1 26  ? 1.54620   -23.82897 13.01823 1.000 22.40922 ? 49  LEU A H    1 
ATOM   355  H  HA   . LEU A 1 26  ? -1.10481  -23.58697 13.51751 1.000 20.78454 ? 49  LEU A HA   1 
ATOM   356  H  HB2  . LEU A 1 26  ? -0.81000  -24.35805 11.37364 1.000 23.24481 ? 49  LEU A HB2  1 
ATOM   357  H  HB3  . LEU A 1 26  ? 0.18169   -25.49280 11.87792 1.000 23.24481 ? 49  LEU A HB3  1 
ATOM   358  H  HG   . LEU A 1 26  ? -1.76432  -26.38986 13.06635 1.000 23.19345 ? 49  LEU A HG   1 
ATOM   359  H  HD11 . LEU A 1 26  ? -3.82082  -25.86837 12.19085 1.000 25.79133 ? 49  LEU A HD11 1 
ATOM   360  H  HD12 . LEU A 1 26  ? -3.13600  -24.54387 12.73877 1.000 25.79133 ? 49  LEU A HD12 1 
ATOM   361  H  HD13 . LEU A 1 26  ? -3.14756  -24.84533 11.17912 1.000 25.79133 ? 49  LEU A HD13 1 
ATOM   362  H  HD21 . LEU A 1 26  ? -2.45036  -27.66484 11.22657 1.000 33.86578 ? 49  LEU A HD21 1 
ATOM   363  H  HD22 . LEU A 1 26  ? -1.68877  -26.66393 10.25618 1.000 33.86578 ? 49  LEU A HD22 1 
ATOM   364  H  HD23 . LEU A 1 26  ? -0.86585  -27.56259 11.27536 1.000 33.86578 ? 49  LEU A HD23 1 
ATOM   365  N  N    . ILE A 1 27  ? -1.20837  -25.19803 15.41889 1.000 19.23544 ? 50  ILE A N    1 
ATOM   366  C  CA   . ILE A 1 27  ? -1.31050  -26.21947 16.46458 1.000 17.33147 ? 50  ILE A CA   1 
ATOM   367  C  C    . ILE A 1 27  ? -2.51214  -27.08982 16.12081 1.000 14.49227 ? 50  ILE A C    1 
ATOM   368  O  O    . ILE A 1 27  ? -3.61425  -26.56890 15.91300 1.000 18.51279 ? 50  ILE A O    1 
ATOM   369  C  CB   . ILE A 1 27  ? -1.46471  -25.60107 17.86810 1.000 14.93686 ? 50  ILE A CB   1 
ATOM   370  C  CG1  . ILE A 1 27  ? -0.21747  -24.81500 18.29270 1.000 20.51179 ? 50  ILE A CG1  1 
ATOM   371  C  CG2  . ILE A 1 27  ? -1.79769  -26.69866 18.87892 1.000 23.55975 ? 50  ILE A CG2  1 
ATOM   372  C  CD1  . ILE A 1 27  ? -0.42585  -23.92311 19.55459 1.000 22.32048 ? 50  ILE A CD1  1 
ATOM   373  H  H    . ILE A 1 27  ? -1.85675  -24.63316 15.42996 1.000 23.06245 ? 50  ILE A H    1 
ATOM   374  H  HA   . ILE A 1 27  ? -0.50775  -26.76398 16.46560 1.000 20.77769 ? 50  ILE A HA   1 
ATOM   375  H  HB   . ILE A 1 27  ? -2.19495  -24.96339 17.83612 1.000 17.90416 ? 50  ILE A HB   1 
ATOM   376  H  HG12 . ILE A 1 27  ? 0.49362   -25.44426 18.49090 1.000 24.59407 ? 50  ILE A HG12 1 
ATOM   377  H  HG13 . ILE A 1 27  ? 0.04734   -24.23446 17.56213 1.000 24.59407 ? 50  ILE A HG13 1 
ATOM   378  H  HG21 . ILE A 1 27  ? -1.71172  -26.33883 19.77560 1.000 28.25162 ? 50  ILE A HG21 1 
ATOM   379  H  HG22 . ILE A 1 27  ? -2.70738  -27.00030 18.72936 1.000 28.25162 ? 50  ILE A HG22 1 
ATOM   380  H  HG23 . ILE A 1 27  ? -1.18031  -27.43701 18.75820 1.000 28.25162 ? 50  ILE A HG23 1 
ATOM   381  H  HD11 . ILE A 1 27  ? 0.35037   -23.35298 19.67002 1.000 26.76450 ? 50  ILE A HD11 1 
ATOM   382  H  HD12 . ILE A 1 27  ? -1.21968  -23.37983 19.42973 1.000 26.76450 ? 50  ILE A HD12 1 
ATOM   383  H  HD13 . ILE A 1 27  ? -0.53486  -24.49461 20.33074 1.000 26.76450 ? 50  ILE A HD13 1 
ATOM   384  N  N    . ASN A 1 28  ? -2.30163  -28.40110 16.00012 1.000 18.24860 ? 51  ASN A N    1 
ATOM   385  C  CA   . ASN A 1 28  ? -3.37542  -29.32959 15.67453 1.000 24.18151 ? 51  ASN A CA   1 
ATOM   386  C  C    . ASN A 1 28  ? -3.67558  -30.12933 16.93421 1.000 18.46604 ? 51  ASN A C    1 
ATOM   387  O  O    . ASN A 1 28  ? -2.84827  -30.93472 17.37605 1.000 20.23744 ? 51  ASN A O    1 
ATOM   388  C  CB   . ASN A 1 28  ? -2.99934  -30.24790 14.52268 1.000 20.38463 ? 51  ASN A CB   1 
ATOM   389  C  CG   . ASN A 1 28  ? -4.14254  -31.12320 14.09700 1.000 31.30059 ? 51  ASN A CG   1 
ATOM   390  O  OD1  . ASN A 1 28  ? -5.16637  -31.20526 14.78260 1.000 23.32319 ? 51  ASN A OD1  1 
ATOM   391  N  ND2  . ASN A 1 28  ? -3.97975  -31.79434 12.96590 1.000 28.64543 ? 51  ASN A ND2  1 
ATOM   392  H  H    . ASN A 1 28  ? -1.53509  -28.77684 16.10421 1.000 21.87823 ? 51  ASN A H    1 
ATOM   393  H  HA   . ASN A 1 28  ? -4.16401  -28.83248 15.40638 1.000 28.99773 ? 51  ASN A HA   1 
ATOM   394  H  HB2  . ASN A 1 28  ? -2.73111  -29.70983 13.76147 1.000 24.44147 ? 51  ASN A HB2  1 
ATOM   395  H  HB3  . ASN A 1 28  ? -2.26679  -30.82069 14.79869 1.000 24.44147 ? 51  ASN A HB3  1 
ATOM   396  H  HD21 . ASN A 1 28  ? -4.60501  -32.30986 12.67799 1.000 34.35444 ? 51  ASN A HD21 1 
ATOM   397  H  HD22 . ASN A 1 28  ? -3.24886  -31.71434 12.51981 1.000 34.35444 ? 51  ASN A HD22 1 
ATOM   398  N  N    . THR A 1 29  ? -4.81982  -29.85290 17.55736 1.000 21.79970 ? 52  THR A N    1 
ATOM   399  C  CA   . THR A 1 29  ? -5.08669  -30.48322 18.84035 1.000 23.50329 ? 52  THR A CA   1 
ATOM   400  C  C    . THR A 1 29  ? -5.54142  -31.92735 18.68870 1.000 29.64504 ? 52  THR A C    1 
ATOM   401  O  O    . THR A 1 29  ? -5.63158  -32.64356 19.69037 1.000 24.68171 ? 52  THR A O    1 
ATOM   402  C  CB   . THR A 1 29  ? -6.11290  -29.67291 19.65141 1.000 22.25617 ? 52  THR A CB   1 
ATOM   403  O  OG1  . THR A 1 29  ? -7.43053  -29.82884 19.11711 1.000 21.51613 ? 52  THR A OG1  1 
ATOM   404  C  CG2  . THR A 1 29  ? -5.74237  -28.19782 19.70159 1.000 22.68207 ? 52  THR A CG2  1 
ATOM   405  H  H    . THR A 1 29  ? -5.43191  -29.32361 17.26616 1.000 26.13956 ? 52  THR A H    1 
ATOM   406  H  HA   . THR A 1 29  ? -4.27048  -30.48284 19.36447 1.000 28.18387 ? 52  THR A HA   1 
ATOM   407  H  HB   . THR A 1 29  ? -6.11160  -30.01015 20.56089 1.000 26.68732 ? 52  THR A HB   1 
ATOM   408  H  HG1  . THR A 1 29  ? -7.46951  -29.49583 18.34693 1.000 25.79928 ? 52  THR A HG1  1 
ATOM   409  H  HG21 . THR A 1 29  ? -6.38515  -27.71249 20.24213 1.000 27.19840 ? 52  THR A HG21 1 
ATOM   410  H  HG22 . THR A 1 29  ? -4.85989  -28.09045 20.08968 1.000 27.19840 ? 52  THR A HG22 1 
ATOM   411  H  HG23 . THR A 1 29  ? -5.73971  -27.82576 18.80579 1.000 27.19840 ? 52  THR A HG23 1 
ATOM   412  N  N    . ALA A 1 30  ? -5.77959  -32.39687 17.45967 1.000 25.22253 ? 53  ALA A N    1 
ATOM   413  C  CA   . ALA A 1 30  ? -6.04609  -33.81634 17.26654 1.000 26.11749 ? 53  ALA A CA   1 
ATOM   414  C  C    . ALA A 1 30  ? -4.87562  -34.66667 17.74022 1.000 25.97020 ? 53  ALA A C    1 
ATOM   415  O  O    . ALA A 1 30  ? -5.07920  -35.72965 18.32987 1.000 30.61344 ? 53  ALA A O    1 
ATOM   416  C  CB   . ALA A 1 30  ? -6.33748  -34.11365 15.80167 1.000 28.46732 ? 53  ALA A CB   1 
ATOM   417  H  H    . ALA A 1 30  ? -5.79148  -31.92361 16.74169 1.000 30.24695 ? 53  ALA A H    1 
ATOM   418  H  HA   . ALA A 1 30  ? -6.83193  -34.04860 17.78559 1.000 31.32090 ? 53  ALA A HA   1 
ATOM   419  H  HB1  . ALA A 1 30  ? -6.53953  -35.05745 15.70511 1.000 34.14070 ? 53  ALA A HB1  1 
ATOM   420  H  HB2  . ALA A 1 30  ? -7.09699  -33.58192 15.51652 1.000 34.14070 ? 53  ALA A HB2  1 
ATOM   421  H  HB3  . ALA A 1 30  ? -5.55720  -33.88654 15.27206 1.000 34.14070 ? 53  ALA A HB3  1 
ATOM   422  N  N    . ASP A 1 31  ? -3.64037  -34.22166 17.48532 1.000 27.71752 ? 54  ASP A N    1 
ATOM   423  C  CA   . ASP A 1 31  ? -2.47355  -35.03072 17.80613 1.000 26.29610 ? 54  ASP A CA   1 
ATOM   424  C  C    . ASP A 1 31  ? -1.38571  -34.23935 18.51514 1.000 24.80557 ? 54  ASP A C    1 
ATOM   425  O  O    . ASP A 1 31  ? -0.30255  -34.78103 18.73767 1.000 26.31582 ? 54  ASP A O    1 
ATOM   426  C  CB   . ASP A 1 31  ? -1.90076  -35.70031 16.54575 1.000 30.56600 ? 54  ASP A CB   1 
ATOM   427  C  CG   . ASP A 1 31  ? -1.43660  -34.70492 15.49952 1.000 27.41255 ? 54  ASP A CG   1 
ATOM   428  O  OD1  . ASP A 1 31  ? -1.59325  -33.48739 15.69550 1.000 23.04877 ? 54  ASP A OD1  1 
ATOM   429  O  OD2  . ASP A 1 31  ? -0.90158  -35.15737 14.47235 1.000 32.94623 ? 54  ASP A OD2  1 
ATOM   430  H  H    . ASP A 1 31  ? -3.45971  -33.45974 17.12974 1.000 33.24094 ? 54  ASP A H    1 
ATOM   431  H  HA   . ASP A 1 31  ? -2.75544  -35.73854 18.40650 1.000 31.53524 ? 54  ASP A HA   1 
ATOM   432  H  HB2  . ASP A 1 31  ? -1.13880  -36.24512 16.79774 1.000 36.65912 ? 54  ASP A HB2  1 
ATOM   433  H  HB3  . ASP A 1 31  ? -2.58763  -36.25568 16.14492 1.000 36.65912 ? 54  ASP A HB3  1 
ATOM   434  N  N    . ASN A 1 32  ? -1.67554  -32.99729 18.91972 1.000 23.28956 ? 55  ASN A N    1 
ATOM   435  C  CA   . ASN A 1 32  ? -0.73023  -32.10022 19.59391 1.000 24.80926 ? 55  ASN A CA   1 
ATOM   436  C  C    . ASN A 1 32  ? 0.47990   -31.79347 18.71575 1.000 26.84009 ? 55  ASN A C    1 
ATOM   437  O  O    . ASN A 1 32  ? 1.58542   -31.57873 19.21649 1.000 30.23742 ? 55  ASN A O    1 
ATOM   438  C  CB   . ASN A 1 32  ? -0.28234  -32.67558 20.94744 1.000 28.19850 ? 55  ASN A CB   1 
ATOM   439  C  CG   . ASN A 1 32  ? 0.14812   -31.59565 21.93218 1.000 25.57513 ? 55  ASN A CG   1 
ATOM   440  O  OD1  . ASN A 1 32  ? -0.31687  -30.46009 21.87001 1.000 29.03532 ? 55  ASN A OD1  1 
ATOM   441  N  ND2  . ASN A 1 32  ? 1.06569   -31.93923 22.83138 1.000 34.93267 ? 55  ASN A ND2  1 
ATOM   442  H  H    . ASN A 1 32  ? -2.44801  -32.63560 18.80990 1.000 27.92739 ? 55  ASN A H    1 
ATOM   443  H  HA   . ASN A 1 32  ? -1.18252  -31.25941 19.76525 1.000 29.75103 ? 55  ASN A HA   1 
ATOM   444  H  HB2  . ASN A 1 32  ? -1.02046  -33.16528 21.34277 1.000 33.81812 ? 55  ASN A HB2  1 
ATOM   445  H  HB3  . ASN A 1 32  ? 0.47127   -33.26942 20.80489 1.000 33.81812 ? 55  ASN A HB3  1 
ATOM   446  H  HD21 . ASN A 1 32  ? 1.33975   -31.36291 23.40787 1.000 41.89912 ? 55  ASN A HD21 1 
ATOM   447  H  HD22 . ASN A 1 32  ? 1.38501   -32.73774 22.83638 1.000 41.89912 ? 55  ASN A HD22 1 
ATOM   448  N  N    . SER A 1 33  ? 0.29228   -31.77493 17.39906 1.000 24.98167 ? 56  SER A N    1 
ATOM   449  C  CA   . SER A 1 33  ? 1.38385   -31.47733 16.48356 1.000 28.57711 ? 56  SER A CA   1 
ATOM   450  C  C    . SER A 1 33  ? 1.39753   -29.99082 16.14421 1.000 28.38991 ? 56  SER A C    1 
ATOM   451  O  O    . SER A 1 33  ? 0.43990   -29.26371 16.38301 1.000 23.42229 ? 56  SER A O    1 
ATOM   452  C  CB   . SER A 1 33  ? 1.29192   -32.31371 15.20063 1.000 24.20819 ? 56  SER A CB   1 
ATOM   453  O  OG   . SER A 1 33  ? 0.13106   -32.02007 14.43563 1.000 26.99866 ? 56  SER A OG   1 
ATOM   454  H  H    . SER A 1 33  ? -0.45998  -31.93194 17.01299 1.000 29.95792 ? 56  SER A H    1 
ATOM   455  H  HA   . SER A 1 33  ? 2.21891   -31.70912 16.91926 1.000 34.27245 ? 56  SER A HA   1 
ATOM   456  H  HB2  . SER A 1 33  ? 2.07389   -32.13055 14.65668 1.000 29.02974 ? 56  SER A HB2  1 
ATOM   457  H  HB3  . SER A 1 33  ? 1.27045   -33.25207 15.44540 1.000 29.02974 ? 56  SER A HB3  1 
ATOM   458  H  HG   . SER A 1 33  ? -0.55870  -32.21072 14.87550 1.000 32.37832 ? 56  SER A HG   1 
ATOM   459  N  N    . GLN A 1 34  ? 2.51028   -29.53977 15.57679 1.000 25.63765 ? 57  GLN A N    1 
ATOM   460  C  CA   . GLN A 1 34  ? 2.67003   -28.15636 15.15527 1.000 16.68780 ? 57  GLN A CA   1 
ATOM   461  C  C    . GLN A 1 34  ? 3.27378   -28.11907 13.76301 1.000 24.35974 ? 57  GLN A C    1 
ATOM   462  O  O    . GLN A 1 34  ? 4.07884   -28.98074 13.40341 1.000 24.76007 ? 57  GLN A O    1 
ATOM   463  C  CB   . GLN A 1 34  ? 3.61386   -27.37617 16.06722 1.000 27.08080 ? 57  GLN A CB   1 
ATOM   464  C  CG   . GLN A 1 34  ? 3.16729   -27.18392 17.49439 1.000 31.85627 ? 57  GLN A CG   1 
ATOM   465  C  CD   . GLN A 1 34  ? 4.22667   -26.47513 18.30621 1.000 42.12148 ? 57  GLN A CD   1 
ATOM   466  O  OE1  . GLN A 1 34  ? 3.98110   -25.40711 18.85882 1.000 43.50221 ? 57  GLN A OE1  1 
ATOM   467  N  NE2  . GLN A 1 34  ? 5.42554   -27.06295 18.36936 1.000 54.81818 ? 57  GLN A NE2  1 
ATOM   468  H  H    . GLN A 1 34  ? 3.20125   -30.02801 15.42258 1.000 30.74510 ? 57  GLN A H    1 
ATOM   469  H  HA   . GLN A 1 34  ? 1.79485   -27.73809 15.16031 1.000 20.00528 ? 57  GLN A HA   1 
ATOM   470  H  HB2  . GLN A 1 34  ? 4.46166   -27.84661 16.09584 1.000 32.47688 ? 57  GLN A HB2  1 
ATOM   471  H  HB3  . GLN A 1 34  ? 3.73748   -26.49247 15.68684 1.000 32.47688 ? 57  GLN A HB3  1 
ATOM   472  H  HG2  . GLN A 1 34  ? 2.35915   -26.64767 17.50976 1.000 38.20744 ? 57  GLN A HG2  1 
ATOM   473  H  HG3  . GLN A 1 34  ? 2.99889   -28.04939 17.89875 1.000 38.20744 ? 57  GLN A HG3  1 
ATOM   474  H  HE21 . GLN A 1 34  ? 5.56184   -27.80679 17.95982 1.000 65.76173 ? 57  GLN A HE21 1 
ATOM   475  H  HE22 . GLN A 1 34  ? 6.06055   -26.69730 18.81954 1.000 65.76173 ? 57  GLN A HE22 1 
ATOM   476  N  N    . ILE A 1 35  ? 2.90626   -27.09028 13.00482 1.000 19.17711 ? 58  ILE A N    1 
ATOM   477  C  CA   . ILE A 1 35  ? 3.60567   -26.67083 11.79754 1.000 20.88592 ? 58  ILE A CA   1 
ATOM   478  C  C    . ILE A 1 35  ? 4.10212   -25.24563 12.03202 1.000 17.55654 ? 58  ILE A C    1 
ATOM   479  O  O    . ILE A 1 35  ? 3.31864   -24.34355 12.36266 1.000 18.61494 ? 58  ILE A O    1 
ATOM   480  C  CB   . ILE A 1 35  ? 2.70049   -26.78081 10.56253 1.000 22.77499 ? 58  ILE A CB   1 
ATOM   481  C  CG1  . ILE A 1 35  ? 2.41083   -28.25968 10.31674 1.000 23.64896 ? 58  ILE A CG1  1 
ATOM   482  C  CG2  . ILE A 1 35  ? 3.39047   -26.17583 9.37200  1.000 25.13553 ? 58  ILE A CG2  1 
ATOM   483  C  CD1  . ILE A 1 35  ? 1.30941   -28.53015 9.33558  1.000 34.40299 ? 58  ILE A CD1  1 
ATOM   484  H  H    . ILE A 1 35  ? 2.22285   -26.59811 13.17893 1.000 22.99245 ? 58  ILE A H    1 
ATOM   485  H  HA   . ILE A 1 35  ? 4.38316   -27.22918 11.64054 1.000 25.04302 ? 58  ILE A HA   1 
ATOM   486  H  HB   . ILE A 1 35  ? 1.86957   -26.30231 10.70915 1.000 27.30990 ? 58  ILE A HB   1 
ATOM   487  H  HG12 . ILE A 1 35  ? 3.21596   -28.67828 9.97406  1.000 28.35867 ? 58  ILE A HG12 1 
ATOM   488  H  HG13 . ILE A 1 35  ? 2.15751   -28.66796 11.15938 1.000 28.35867 ? 58  ILE A HG13 1 
ATOM   489  H  HG21 . ILE A 1 35  ? 2.90582   -26.42037 8.56813  1.000 30.14256 ? 58  ILE A HG21 1 
ATOM   490  H  HG22 . ILE A 1 35  ? 3.40230   -25.21091 9.47047  1.000 30.14256 ? 58  ILE A HG22 1 
ATOM   491  H  HG23 . ILE A 1 35  ? 4.29816   -26.51489 9.32704  1.000 30.14256 ? 58  ILE A HG23 1 
ATOM   492  H  HD11 . ILE A 1 35  ? 1.04190   -29.45960 9.40941  1.000 41.26351 ? 58  ILE A HD11 1 
ATOM   493  H  HD12 . ILE A 1 35  ? 0.55709   -27.95232 9.53813  1.000 41.26351 ? 58  ILE A HD12 1 
ATOM   494  H  HD13 . ILE A 1 35  ? 1.63343   -28.34940 8.43934  1.000 41.26351 ? 58  ILE A HD13 1 
ATOM   495  N  N    . LEU A 1 36  ? 5.41035   -25.05028 11.89299 1.000 19.44494 ? 59  LEU A N    1 
ATOM   496  C  CA   . LEU A 1 36  ? 6.03441   -23.79435 12.26270 1.000 21.49260 ? 59  LEU A CA   1 
ATOM   497  C  C    . LEU A 1 36  ? 6.86240   -23.25660 11.11470 1.000 20.83026 ? 59  LEU A C    1 
ATOM   498  O  O    . LEU A 1 36  ? 7.58543   -24.00705 10.46707 1.000 23.41329 ? 59  LEU A O    1 
ATOM   499  C  CB   . LEU A 1 36  ? 6.92399   -23.97478 13.47210 1.000 23.28584 ? 59  LEU A CB   1 
ATOM   500  C  CG   . LEU A 1 36  ? 6.32376   -24.65936 14.69420 1.000 22.29383 ? 59  LEU A CG   1 
ATOM   501  C  CD1  . LEU A 1 36  ? 7.40415   -24.97786 15.69259 1.000 25.76103 ? 59  LEU A CD1  1 
ATOM   502  C  CD2  . LEU A 1 36  ? 5.27258   -23.76459 15.28345 1.000 21.97068 ? 59  LEU A CD2  1 
ATOM   503  H  H    . LEU A 1 36  ? 5.95715   -25.63774 11.58396 1.000 23.31384 ? 59  LEU A H    1 
ATOM   504  H  HA   . LEU A 1 36  ? 5.34275   -23.14443 12.46299 1.000 25.77104 ? 59  LEU A HA   1 
ATOM   505  H  HB2  . LEU A 1 36  ? 7.68872   -24.50615 13.20054 1.000 27.92293 ? 59  LEU A HB2  1 
ATOM   506  H  HB3  . LEU A 1 36  ? 7.21605   -23.09531 13.75870 1.000 27.92293 ? 59  LEU A HB3  1 
ATOM   507  H  HG   . LEU A 1 36  ? 5.90729   -25.50000 14.44770 1.000 26.73252 ? 59  LEU A HG   1 
ATOM   508  H  HD11 . LEU A 1 36  ? 7.00362   -25.40528 16.46576 1.000 30.89316 ? 59  LEU A HD11 1 
ATOM   509  H  HD12 . LEU A 1 36  ? 8.04828   -25.57511 15.28113 1.000 30.89316 ? 59  LEU A HD12 1 
ATOM   510  H  HD13 . LEU A 1 36  ? 7.84061   -24.15369 15.95932 1.000 30.89316 ? 59  LEU A HD13 1 
ATOM   511  H  HD21 . LEU A 1 36  ? 4.87422   -24.20713 16.04920 1.000 26.34474 ? 59  LEU A HD21 1 
ATOM   512  H  HD22 . LEU A 1 36  ? 5.68579   -22.93193 15.56061 1.000 26.34474 ? 59  LEU A HD22 1 
ATOM   513  H  HD23 . LEU A 1 36  ? 4.59420   -23.58994 14.61248 1.000 26.34474 ? 59  LEU A HD23 1 
ATOM   514  N  N    . TYR A 1 37  ? 6.78025   -21.95079 10.88412 1.000 17.39897 ? 60  TYR A N    1 
ATOM   515  C  CA   . TYR A 1 37  ? 7.57311   -21.31156 9.82977  1.000 15.27018 ? 60  TYR A CA   1 
ATOM   516  C  C    . TYR A 1 37  ? 7.95540   -19.93841 10.37853 1.000 16.48098 ? 60  TYR A C    1 
ATOM   517  O  O    . TYR A 1 37  ? 7.08044   -19.11354 10.62615 1.000 16.57878 ? 60  TYR A O    1 
ATOM   518  C  CB   . TYR A 1 37  ? 6.80628   -21.21294 8.49757  1.000 16.65017 ? 60  TYR A CB   1 
ATOM   519  C  CG   . TYR A 1 37  ? 7.70082   -20.72034 7.39461  1.000 18.68242 ? 60  TYR A CG   1 
ATOM   520  C  CD1  . TYR A 1 37  ? 8.44713   -21.62401 6.64478  1.000 21.09071 ? 60  TYR A CD1  1 
ATOM   521  C  CD2  . TYR A 1 37  ? 7.85676   -19.34457 7.13091  1.000 17.80876 ? 60  TYR A CD2  1 
ATOM   522  C  CE1  . TYR A 1 37  ? 9.29647   -21.20105 5.66432  1.000 24.05235 ? 60  TYR A CE1  1 
ATOM   523  C  CE2  . TYR A 1 37  ? 8.74352   -18.91183 6.14073  1.000 21.88184 ? 60  TYR A CE2  1 
ATOM   524  C  CZ   . TYR A 1 37  ? 9.44614   -19.84787 5.41154  1.000 28.33148 ? 60  TYR A CZ   1 
ATOM   525  O  OH   . TYR A 1 37  ? 10.31771  -19.45115 4.41189  1.000 21.41517 ? 60  TYR A OH   1 
ATOM   526  H  H    . TYR A 1 37  ? 6.27402   -21.41127 11.32259 1.000 20.85868 ? 60  TYR A H    1 
ATOM   527  H  HA   . TYR A 1 37  ? 8.37453   -21.82446 9.64119  1.000 18.30414 ? 60  TYR A HA   1 
ATOM   528  H  HB2  . TYR A 1 37  ? 6.47099   -22.08971 8.25310  1.000 19.96013 ? 60  TYR A HB2  1 
ATOM   529  H  HB3  . TYR A 1 37  ? 6.06833   -20.59110 8.59581  1.000 19.96013 ? 60  TYR A HB3  1 
ATOM   530  H  HD1  . TYR A 1 37  ? 8.36542   -22.53458 6.81530  1.000 25.28877 ? 60  TYR A HD1  1 
ATOM   531  H  HD2  . TYR A 1 37  ? 7.36730   -18.72165 7.61806  1.000 21.35043 ? 60  TYR A HD2  1 
ATOM   532  H  HE1  . TYR A 1 37  ? 9.77555   -21.82246 5.16508  1.000 28.84274 ? 60  TYR A HE1  1 
ATOM   533  H  HE2  . TYR A 1 37  ? 8.85822   -18.00379 5.97578  1.000 26.23813 ? 60  TYR A HE2  1 
ATOM   534  H  HH   . TYR A 1 37  ? 10.33855  -18.61272 4.36496  1.000 25.67812 ? 60  TYR A HH   1 
ATOM   535  N  N    . ARG A 1 38  ? 9.24440   -19.71074 10.63894 1.000 15.22647 ? 61  ARG A N    1 
ATOM   536  C  CA   . ARG A 1 38  ? 9.69006   -18.47807 11.30595 1.000 14.21827 ? 61  ARG A CA   1 
ATOM   537  C  C    . ARG A 1 38  ? 8.88885   -18.21296 12.58144 1.000 20.00648 ? 61  ARG A C    1 
ATOM   538  O  O    . ARG A 1 38  ? 8.63339   -17.06338 12.93784 1.000 19.23615 ? 61  ARG A O    1 
ATOM   539  C  CB   . ARG A 1 38  ? 9.57859   -17.26963 10.37138 1.000 16.95270 ? 61  ARG A CB   1 
ATOM   540  C  CG   . ARG A 1 38  ? 10.46248  -17.34292 9.12435  1.000 18.83017 ? 61  ARG A CG   1 
ATOM   541  C  CD   . ARG A 1 38  ? 10.51726  -15.99695 8.39729  1.000 18.26494 ? 61  ARG A CD   1 
ATOM   542  N  NE   . ARG A 1 38  ? 11.18291  -16.09774 7.10499  1.000 21.06268 ? 61  ARG A NE   1 
ATOM   543  C  CZ   . ARG A 1 38  ? 12.48041  -16.30964 6.92568  1.000 20.34570 ? 61  ARG A CZ   1 
ATOM   544  N  NH1  . ARG A 1 38  ? 13.32603  -16.37985 7.94303  1.000 23.11474 ? 61  ARG A NH1  1 
ATOM   545  N  NH2  . ARG A 1 38  ? 12.94021  -16.49218 5.69175  1.000 23.63461 ? 61  ARG A NH2  1 
ATOM   546  H  H    . ARG A 1 38  ? 9.88195   -20.25272 10.44046 1.000 18.25168 ? 61  ARG A H    1 
ATOM   547  H  HA   . ARG A 1 38  ? 10.62136  -18.59541 11.55054 1.000 17.04185 ? 61  ARG A HA   1 
ATOM   548  H  HB2  . ARG A 1 38  ? 8.65856   -17.19419 10.07346 1.000 20.32316 ? 61  ARG A HB2  1 
ATOM   549  H  HB3  . ARG A 1 38  ? 9.83399   -16.47418 10.86427 1.000 20.32316 ? 61  ARG A HB3  1 
ATOM   550  H  HG2  . ARG A 1 38  ? 11.36486  -17.58650 9.38373  1.000 22.57612 ? 61  ARG A HG2  1 
ATOM   551  H  HG3  . ARG A 1 38  ? 10.10264  -18.00511 8.51368  1.000 22.57612 ? 61  ARG A HG3  1 
ATOM   552  H  HD2  . ARG A 1 38  ? 9.61330   -15.67848 8.24781  1.000 21.89784 ? 61  ARG A HD2  1 
ATOM   553  H  HD3  . ARG A 1 38  ? 11.00748  -15.36070 8.94114  1.000 21.89784 ? 61  ARG A HD3  1 
ATOM   554  H  HE   . ARG A 1 38  ? 10.69537  -16.01303 6.40161  1.000 25.25514 ? 61  ARG A HE   1 
ATOM   555  H  HH11 . ARG A 1 38  ? 13.03863  -16.28709 8.74826  1.000 27.71760 ? 61  ARG A HH11 1 
ATOM   556  H  HH12 . ARG A 1 38  ? 14.16239  -16.51819 7.79823  1.000 27.71760 ? 61  ARG A HH12 1 
ATOM   557  H  HH21 . ARG A 1 38  ? 12.39891  -16.47196 5.02378  1.000 28.34145 ? 61  ARG A HH21 1 
ATOM   558  H  HH22 . ARG A 1 38  ? 13.77896  -16.63048 5.56148  1.000 28.34145 ? 61  ARG A HH22 1 
ATOM   559  N  N    . ALA A 1 39  ? 8.48630   -19.27983 13.27428 1.000 20.73151 ? 62  ALA A N    1 
ATOM   560  C  CA   . ALA A 1 39  ? 7.53765   -19.16093 14.37794 1.000 15.51330 ? 62  ALA A CA   1 
ATOM   561  C  C    . ALA A 1 39  ? 8.15356   -18.52399 15.61056 1.000 19.74561 ? 62  ALA A C    1 
ATOM   562  O  O    . ALA A 1 39  ? 7.40946   -18.19443 16.54214 1.000 17.50230 ? 62  ALA A O    1 
ATOM   563  C  CB   . ALA A 1 39  ? 6.96492   -20.54086 14.71853 1.000 14.88425 ? 62  ALA A CB   1 
ATOM   564  H  H    . ALA A 1 39  ? 8.74915   -20.08468 13.12358 1.000 24.85774 ? 62  ALA A H    1 
ATOM   565  H  HA   . ALA A 1 39  ? 6.79800   -18.59742 14.10176 1.000 18.59588 ? 62  ALA A HA   1 
ATOM   566  H  HB1  . ALA A 1 39  ? 6.33609   -20.44966 15.45144 1.000 17.84102 ? 62  ALA A HB1  1 
ATOM   567  H  HB2  . ALA A 1 39  ? 6.51317   -20.89685 13.93745 1.000 17.84102 ? 62  ALA A HB2  1 
ATOM   568  H  HB3  . ALA A 1 39  ? 7.69141   -21.12922 14.97729 1.000 17.84102 ? 62  ALA A HB3  1 
ATOM   569  N  N    . ASP A 1 40  ? 9.47757   -18.37099 15.65989 1.000 16.62273 ? 63  ASP A N    1 
ATOM   570  C  CA   . ASP A 1 40  ? 10.14775  -17.70113 16.76651 1.000 19.15534 ? 63  ASP A CA   1 
ATOM   571  C  C    . ASP A 1 40  ? 10.65982  -16.32002 16.38858 1.000 21.60805 ? 63  ASP A C    1 
ATOM   572  O  O    . ASP A 1 40  ? 11.33798  -15.68338 17.19539 1.000 22.63161 ? 63  ASP A O    1 
ATOM   573  C  CB   . ASP A 1 40  ? 11.30086  -18.55586 17.29768 1.000 17.02806 ? 63  ASP A CB   1 
ATOM   574  C  CG   . ASP A 1 40  ? 10.82489  -19.85892 17.86907 1.000 26.73820 ? 63  ASP A CG   1 
ATOM   575  O  OD1  . ASP A 1 40  ? 9.84796   -19.82255 18.65903 1.000 20.55945 ? 63  ASP A OD1  1 
ATOM   576  O  OD2  . ASP A 1 40  ? 11.39588  -20.91309 17.50176 1.000 22.15462 ? 63  ASP A OD2  1 
ATOM   577  H  H    . ASP A 1 40  ? 10.01582  -18.65306 15.05135 1.000 19.92719 ? 63  ASP A H    1 
ATOM   578  H  HA   . ASP A 1 40  ? 9.50484   -17.59506 17.48506 1.000 22.96632 ? 63  ASP A HA   1 
ATOM   579  H  HB2  . ASP A 1 40  ? 11.91364  -18.75025 16.57130 1.000 20.41359 ? 63  ASP A HB2  1 
ATOM   580  H  HB3  . ASP A 1 40  ? 11.76131  -18.06867 17.99877 1.000 20.41359 ? 63  ASP A HB3  1 
ATOM   581  N  N    . GLU A 1 41  ? 10.35823  -15.83903 15.19536 1.000 20.90305 ? 64  GLU A N    1 
ATOM   582  C  CA   . GLU A 1 41  ? 10.72822  -14.47392 14.84316 1.000 19.77015 ? 64  GLU A CA   1 
ATOM   583  C  C    . GLU A 1 41  ? 9.62083   -13.53997 15.29433 1.000 20.67767 ? 64  GLU A C    1 
ATOM   584  O  O    . GLU A 1 41  ? 8.46190   -13.94286 15.43751 1.000 19.07152 ? 64  GLU A O    1 
ATOM   585  C  CB   . GLU A 1 41  ? 10.94412  -14.31077 13.34468 1.000 22.31592 ? 64  GLU A CB   1 
ATOM   586  C  CG   . GLU A 1 41  ? 12.02083  -15.23073 12.80789 1.000 17.24685 ? 64  GLU A CG   1 
ATOM   587  C  CD   . GLU A 1 41  ? 12.37546  -14.91175 11.36588 1.000 22.62955 ? 64  GLU A CD   1 
ATOM   588  O  OE1  . GLU A 1 41  ? 11.99170  -13.81280 10.88158 1.000 18.78483 ? 64  GLU A OE1  1 
ATOM   589  O  OE2  . GLU A 1 41  ? 13.06732  -15.74903 10.73917 1.000 21.87729 ? 64  GLU A OE2  1 
ATOM   590  H  H    . GLU A 1 41  ? 9.94579   -16.27453 14.57906 1.000 25.06358 ? 64  GLU A H    1 
ATOM   591  H  HA   . GLU A 1 41  ? 11.56390  -14.24224 15.27774 1.000 23.70410 ? 64  GLU A HA   1 
ATOM   592  H  HB2  . GLU A 1 41  ? 10.11623  -14.51417 12.88193 1.000 26.75902 ? 64  GLU A HB2  1 
ATOM   593  H  HB3  . GLU A 1 41  ? 11.21064  -13.39631 13.16132 1.000 26.75902 ? 64  GLU A HB3  1 
ATOM   594  H  HG2  . GLU A 1 41  ? 12.82190  -15.13215 13.34591 1.000 20.67614 ? 64  GLU A HG2  1 
ATOM   595  H  HG3  . GLU A 1 41  ? 11.70574  -16.14730 12.84685 1.000 20.67614 ? 64  GLU A HG3  1 
ATOM   596  N  N    . ARG A 1 42  ? 9.98729   -12.28611 15.53932 1.000 16.58271 ? 65  ARG A N    1 
ATOM   597  C  CA   . ARG A 1 42  ? 9.01225   -11.29194 15.96055 1.000 18.36399 ? 65  ARG A CA   1 
ATOM   598  C  C    . ARG A 1 42  ? 8.35176   -10.64150 14.74917 1.000 16.71109 ? 65  ARG A C    1 
ATOM   599  O  O    . ARG A 1 42  ? 9.01330   -10.36831 13.74372 1.000 15.85347 ? 65  ARG A O    1 
ATOM   600  C  CB   . ARG A 1 42  ? 9.68321   -10.22701 16.80747 1.000 16.74699 ? 65  ARG A CB   1 
ATOM   601  C  CG   . ARG A 1 42  ? 9.97395   -10.71235 18.21610 1.000 18.80918 ? 65  ARG A CG   1 
ATOM   602  C  CD   . ARG A 1 42  ? 10.41055  -9.59882  19.13412 1.000 22.80337 ? 65  ARG A CD   1 
ATOM   603  N  NE   . ARG A 1 42  ? 10.58656  -10.11856 20.48910 1.000 24.32614 ? 65  ARG A NE   1 
ATOM   604  C  CZ   . ARG A 1 42  ? 9.60632   -10.21472 21.37424 1.000 19.57533 ? 65  ARG A CZ   1 
ATOM   605  N  NH1  . ARG A 1 42  ? 8.38588   -9.80006  21.09362 1.000 16.36406 ? 65  ARG A NH1  1 
ATOM   606  N  NH2  . ARG A 1 42  ? 9.85836   -10.74893 22.55777 1.000 20.62206 ? 65  ARG A NH2  1 
ATOM   607  H  H    . ARG A 1 42  ? 10.79155  -11.98989 15.46849 1.000 19.87917 ? 65  ARG A H    1 
ATOM   608  H  HA   . ARG A 1 42  ? 8.32116   -11.72305 16.48727 1.000 22.01670 ? 65  ARG A HA   1 
ATOM   609  H  HB2  . ARG A 1 42  ? 10.52410  -9.97571  16.39438 1.000 20.07631 ? 65  ARG A HB2  1 
ATOM   610  H  HB3  . ARG A 1 42  ? 9.09942   -9.45471  16.86795 1.000 20.07631 ? 65  ARG A HB3  1 
ATOM   611  H  HG2  . ARG A 1 42  ? 9.17035   -11.10940 18.58687 1.000 22.55094 ? 65  ARG A HG2  1 
ATOM   612  H  HG3  . ARG A 1 42  ? 10.68513  -11.37120 18.18401 1.000 22.55094 ? 65  ARG A HG3  1 
ATOM   613  H  HD2  . ARG A 1 42  ? 11.25489  -9.23286  18.82743 1.000 27.34396 ? 65  ARG A HD2  1 
ATOM   614  H  HD3  . ARG A 1 42  ? 9.73432   -8.90361  19.15125 1.000 27.34396 ? 65  ARG A HD3  1 
ATOM   615  H  HE   . ARG A 1 42  ? 11.37220  -10.37682 20.72503 1.000 29.17129 ? 65  ARG A HE   1 
ATOM   616  H  HH11 . ARG A 1 42  ? 8.21412   -9.45913  20.32300 1.000 19.61680 ? 65  ARG A HH11 1 
ATOM   617  H  HH12 . ARG A 1 42  ? 7.76198   -9.87066  21.68131 1.000 19.61680 ? 65  ARG A HH12 1 
ATOM   618  H  HH21 . ARG A 1 42  ? 10.65024  -11.02813 22.74370 1.000 24.72639 ? 65  ARG A HH21 1 
ATOM   619  H  HH22 . ARG A 1 42  ? 9.23033   -10.81707 23.14134 1.000 24.72639 ? 65  ARG A HH22 1 
ATOM   620  N  N    . PHE A 1 43  ? 7.05086   -10.37809 14.87246 1.000 15.26490 ? 66  PHE A N    1 
ATOM   621  C  CA   . PHE A 1 43  ? 6.25068   -9.64499  13.89406 1.000 17.20190 ? 66  PHE A CA   1 
ATOM   622  C  C    . PHE A 1 43  ? 5.40886   -8.61639  14.64712 1.000 16.45021 ? 66  PHE A C    1 
ATOM   623  O  O    . PHE A 1 43  ? 4.90933   -8.90847  15.73712 1.000 16.19414 ? 66  PHE A O    1 
ATOM   624  C  CB   . PHE A 1 43  ? 5.29199   -10.56894 13.12754 1.000 17.74157 ? 66  PHE A CB   1 
ATOM   625  C  CG   . PHE A 1 43  ? 5.97593   -11.56986 12.26089 1.000 18.18751 ? 66  PHE A CG   1 
ATOM   626  C  CD1  . PHE A 1 43  ? 6.58948   -12.67916 12.81814 1.000 15.94762 ? 66  PHE A CD1  1 
ATOM   627  C  CD2  . PHE A 1 43  ? 6.01453   -11.38630 10.88099 1.000 17.86310 ? 66  PHE A CD2  1 
ATOM   628  C  CE1  . PHE A 1 43  ? 7.24667   -13.61100 12.02586 1.000 19.59412 ? 66  PHE A CE1  1 
ATOM   629  C  CE2  . PHE A 1 43  ? 6.67322   -12.32302 10.06680 1.000 18.44154 ? 66  PHE A CE2  1 
ATOM   630  C  CZ   . PHE A 1 43  ? 7.27095   -13.44130 10.63470 1.000 16.76884 ? 66  PHE A CZ   1 
ATOM   631  H  H    . PHE A 1 43  ? 6.58532   -10.62758 15.55116 1.000 18.29780 ? 66  PHE A H    1 
ATOM   632  H  HA   . PHE A 1 43  ? 6.83935   -9.21075  13.25703 1.000 20.62220 ? 66  PHE A HA   1 
ATOM   633  H  HB2  . PHE A 1 43  ? 4.75027   -11.05529 13.76855 1.000 21.26981 ? 66  PHE A HB2  1 
ATOM   634  H  HB3  . PHE A 1 43  ? 4.72481   -10.02518 12.55874 1.000 21.26981 ? 66  PHE A HB3  1 
ATOM   635  H  HD1  . PHE A 1 43  ? 6.56086   -12.80224 13.73952 1.000 19.11707 ? 66  PHE A HD1  1 
ATOM   636  H  HD2  . PHE A 1 43  ? 5.60461   -10.64423 10.49864 1.000 21.41564 ? 66  PHE A HD2  1 
ATOM   637  H  HE1  . PHE A 1 43  ? 7.66791   -14.34282 12.41560 1.000 23.49287 ? 66  PHE A HE1  1 
ATOM   638  H  HE2  . PHE A 1 43  ? 6.70916   -12.19430 9.14645  1.000 22.10977 ? 66  PHE A HE2  1 
ATOM   639  H  HZ   . PHE A 1 43  ? 7.68537   -14.07451 10.09415 1.000 20.10253 ? 66  PHE A HZ   1 
ATOM   640  N  N    . ALA A 1 44  ? 5.19415   -7.44688  14.04996 1.000 14.28396 ? 67  ALA A N    1 
ATOM   641  C  CA   . ALA A 1 44  ? 4.28304   -6.47784  14.64332 1.000 15.21214 ? 67  ALA A CA   1 
ATOM   642  C  C    . ALA A 1 44  ? 2.86048   -7.02302  14.64271 1.000 16.12506 ? 67  ALA A C    1 
ATOM   643  O  O    . ALA A 1 44  ? 2.33492   -7.42837  13.60997 1.000 15.47452 ? 67  ALA A O    1 
ATOM   644  C  CB   . ALA A 1 44  ? 4.35368   -5.16341  13.88155 1.000 21.81253 ? 67  ALA A CB   1 
ATOM   645  H  H    . ALA A 1 44  ? 5.55846   -7.19565  13.31256 1.000 17.12068 ? 67  ALA A H    1 
ATOM   646  H  HA   . ALA A 1 44  ? 4.53979   -6.30881  15.56332 1.000 18.23449 ? 67  ALA A HA   1 
ATOM   647  H  HB1  . ALA A 1 44  ? 3.75334   -4.52487  14.29719 1.000 26.15496 ? 67  ALA A HB1  1 
ATOM   648  H  HB2  . ALA A 1 44  ? 5.26394   -4.82958  13.91150 1.000 26.15496 ? 67  ALA A HB2  1 
ATOM   649  H  HB3  . ALA A 1 44  ? 4.08779   -5.31696  12.96143 1.000 26.15496 ? 67  ALA A HB3  1 
ATOM   650  N  N    . MET A 1 45  ? 2.22811   -7.03805  15.81321 1.000 13.84858 ? 68  MET A N    1 
ATOM   651  C  CA   . MET A 1 45  ? 0.93382   -7.71098  15.91787 1.000 12.90084 ? 68  MET A CA   1 
ATOM   652  C  C    . MET A 1 45  ? -0.19070  -6.92019  15.27426 1.000 12.71434 ? 68  MET A C    1 
ATOM   653  O  O    . MET A 1 45  ? -1.18946  -7.50322  14.80627 1.000 14.87436 ? 68  MET A O    1 
ATOM   654  C  CB   . MET A 1 45  ? 0.58099   -7.92817  17.39033 1.000 13.24326 ? 68  MET A CB   1 
ATOM   655  C  CG   . MET A 1 45  ? 1.41469   -8.94462  18.13313 1.000 14.44155 ? 68  MET A CG   1 
ATOM   656  S  SD   . MET A 1 45  ? 0.92113   -8.98807  19.87904 1.000 16.07724 ? 68  MET A SD   1 
ATOM   657  C  CE   . MET A 1 45  ? 1.74925   -7.52739  20.49001 1.000 15.09891 ? 68  MET A CE   1 
ATOM   658  H  H    . MET A 1 45  ? 2.51560   -6.67845  16.53960 1.000 16.59821 ? 68  MET A H    1 
ATOM   659  H  HA   . MET A 1 45  ? 1.01922   -8.56723  15.47016 1.000 15.46092 ? 68  MET A HA   1 
ATOM   660  H  HB2  . MET A 1 45  ? 0.68280   -7.08199  17.85348 1.000 15.87183 ? 68  MET A HB2  1 
ATOM   661  H  HB3  . MET A 1 45  ? -0.34133  -8.22446  17.43957 1.000 15.87183 ? 68  MET A HB3  1 
ATOM   662  H  HG2  . MET A 1 45  ? 1.27799   -9.82432  17.74800 1.000 17.30978 ? 68  MET A HG2  1 
ATOM   663  H  HG3  . MET A 1 45  ? 2.35208   -8.70103  18.07959 1.000 17.30978 ? 68  MET A HG3  1 
ATOM   664  H  HE1  . MET A 1 45  ? 1.60583   -7.46005  21.44698 1.000 18.09861 ? 68  MET A HE1  1 
ATOM   665  H  HE2  . MET A 1 45  ? 2.69806   -7.60039  20.30205 1.000 18.09861 ? 68  MET A HE2  1 
ATOM   666  H  HE3  . MET A 1 45  ? 1.38294   -6.74725  20.04493 1.000 18.09861 ? 68  MET A HE3  1 
ATOM   667  N  N    . CYS A 1 46  ? -0.06386  -5.59742  15.24124 1.000 15.64429 ? 69  CYS A N    1 
ATOM   668  C  CA   . CYS A 1 46  ? -1.17214  -4.73953  14.83587 1.000 17.11993 ? 69  CYS A CA   1 
ATOM   669  C  C    . CYS A 1 46  ? -2.44771  -5.16430  15.56504 1.000 16.96012 ? 69  CYS A C    1 
ATOM   670  O  O    . CYS A 1 46  ? -2.41528  -5.49573  16.76828 1.000 14.46329 ? 69  CYS A O    1 
ATOM   671  C  CB   . CYS A 1 46  ? -1.32426  -4.74990  13.30631 1.000 15.21321 ? 69  CYS A CB   1 
ATOM   672  S  SG   . CYS A 1 46  ? 0.24155   -4.10742  12.55170 1.000 16.73059 ? 69  CYS A SG   1 
ATOM   673  H  H    . CYS A 1 46  ? 0.65404   -5.17190  15.44897 1.000 18.75307 ? 69  CYS A H    1 
ATOM   674  H  HA   . CYS A 1 46  ? -1.00005  -3.81687  15.08077 1.000 20.52383 ? 69  CYS A HA   1 
ATOM   675  H  HB2  . CYS A 1 46  ? -1.47887  -5.65542  12.99481 1.000 18.23577 ? 69  CYS A HB2  1 
ATOM   676  H  HB3  . CYS A 1 46  ? -2.06200  -4.17789  13.04279 1.000 18.23577 ? 69  CYS A HB3  1 
ATOM   677  H  HG   . CYS A 1 46  ? 0.16431   -4.19506  11.35740 1.000 20.05663 ? 69  CYS A HG   1 
ATOM   678  N  N    . SER A 1 47  ? -3.58489  -5.12446  14.87813 1.000 14.77024 ? 70  SER A N    1 
ATOM   679  C  CA   . SER A 1 47  ? -4.83690  -5.34114  15.59755 1.000 14.95223 ? 70  SER A CA   1 
ATOM   680  C  C    . SER A 1 47  ? -5.00036  -6.75680  16.15716 1.000 14.32475 ? 70  SER A C    1 
ATOM   681  O  O    . SER A 1 47  ? -5.92900  -6.97204  16.94493 1.000 16.74149 ? 70  SER A O    1 
ATOM   682  C  CB   . SER A 1 47  ? -6.04043  -5.01943  14.69876 1.000 14.19654 ? 70  SER A CB   1 
ATOM   683  O  OG   . SER A 1 47  ? -6.09024  -3.62775  14.44442 1.000 13.77775 ? 70  SER A OG   1 
ATOM   684  H  H    . SER A 1 47  ? -3.65608  -4.98039  14.03328 1.000 17.70420 ? 70  SER A H    1 
ATOM   685  H  HA   . SER A 1 47  ? -4.83997  -4.72737  16.34866 1.000 17.92259 ? 70  SER A HA   1 
ATOM   686  H  HB2  . SER A 1 47  ? -5.94845  -5.49517  13.85846 1.000 17.01577 ? 70  SER A HB2  1 
ATOM   687  H  HB3  . SER A 1 47  ? -6.85635  -5.29219  15.14685 1.000 17.01577 ? 70  SER A HB3  1 
ATOM   688  N  N    . THR A 1 48  ? -4.12235  -7.71207  15.84013 1.000 14.36396 ? 71  THR A N    1 
ATOM   689  C  CA   . THR A 1 48  ? -4.28852  -9.01036  16.49655 1.000 13.15538 ? 71  THR A CA   1 
ATOM   690  C  C    . THR A 1 48  ? -4.05950  -8.89061  17.99678 1.000 14.15726 ? 71  THR A C    1 
ATOM   691  O  O    . THR A 1 48  ? -4.49280  -9.76708  18.75458 1.000 14.13816 ? 71  THR A O    1 
ATOM   692  C  CB   . THR A 1 48  ? -3.39086  -10.11435 15.90794 1.000 17.26508 ? 71  THR A CB   1 
ATOM   693  O  OG1  . THR A 1 48  ? -1.99348  -9.84362  16.06454 1.000 15.22514 ? 71  THR A OG1  1 
ATOM   694  C  CG2  . THR A 1 48  ? -3.70238  -10.30753 14.41962 1.000 16.02619 ? 71  THR A CG2  1 
ATOM   695  H  H    . THR A 1 48  ? -3.46780  -7.63890  15.28712 1.000 17.21667 ? 71  THR A H    1 
ATOM   696  H  HA   . THR A 1 48  ? -5.19407  -9.31137  16.32255 1.000 15.76637 ? 71  THR A HA   1 
ATOM   697  H  HB   . THR A 1 48  ? -3.57823  -10.93135 16.39609 1.000 20.69802 ? 71  THR A HB   1 
ATOM   698  H  HG1  . THR A 1 48  ? -1.77900  -9.16928  15.61192 1.000 18.25008 ? 71  THR A HG1  1 
ATOM   699  H  HG21 . THR A 1 48  ? -3.25187  -11.09931 14.08641 1.000 19.21134 ? 71  THR A HG21 1 
ATOM   700  H  HG22 . THR A 1 48  ? -4.65822  -10.41185 14.29155 1.000 19.21134 ? 71  THR A HG22 1 
ATOM   701  H  HG23 . THR A 1 48  ? -3.39935  -9.53687  13.91448 1.000 19.21134 ? 71  THR A HG23 1 
ATOM   702  N  N    . SER A 1 49  ? -3.41821  -7.80223  18.43902 1.000 13.85457 ? 72  SER A N    1 
ATOM   703  C  CA   . SER A 1 49  ? -3.19678  -7.56010  19.86301 1.000 14.09512 ? 72  SER A CA   1 
ATOM   704  C  C    . SER A 1 49  ? -4.50462  -7.29397  20.60963 1.000 16.01127 ? 72  SER A C    1 
ATOM   705  O  O    . SER A 1 49  ? -4.52933  -7.38296  21.84071 1.000 15.76163 ? 72  SER A O    1 
ATOM   706  C  CB   . SER A 1 49  ? -2.22154  -6.39819  20.06540 1.000 16.45012 ? 72  SER A CB   1 
ATOM   707  O  OG   . SER A 1 49  ? -2.71771  -5.17210  19.56934 1.000 17.61890 ? 72  SER A OG   1 
ATOM   708  H  H    . SER A 1 49  ? -3.10074  -7.18682  17.92904 1.000 16.60540 ? 72  SER A H    1 
ATOM   709  H  HA   . SER A 1 49  ? -2.78218  -8.34460  20.25488 1.000 16.89407 ? 72  SER A HA   1 
ATOM   710  H  HB2  . SER A 1 49  ? -2.05307  -6.29997  21.01559 1.000 19.72006 ? 72  SER A HB2  1 
ATOM   711  H  HB3  . SER A 1 49  ? -1.39525  -6.60581  19.60168 1.000 19.72006 ? 72  SER A HB3  1 
ATOM   712  H  HG   . SER A 1 49  ? -2.92368  -5.25231  18.75895 1.000 21.12260 ? 72  SER A HG   1 
ATOM   713  N  N    . LYS A 1 50  ? -5.60236  -7.01105  19.90089 1.000 14.71847 ? 73  LYS A N    1 
ATOM   714  C  CA   . LYS A 1 50  ? -6.85887  -6.70495  20.59428 1.000 16.34188 ? 73  LYS A CA   1 
ATOM   715  C  C    . LYS A 1 50  ? -7.40189  -7.91965  21.34038 1.000 14.65565 ? 73  LYS A C    1 
ATOM   716  O  O    . LYS A 1 50  ? -8.16149  -7.76851  22.32077 1.000 15.63053 ? 73  LYS A O    1 
ATOM   717  C  CB   . LYS A 1 50  ? -7.87221  -6.15955  19.56505 1.000 16.40135 ? 73  LYS A CB   1 
ATOM   718  C  CG   . LYS A 1 50  ? -7.44379  -4.77703  19.01410 1.000 19.00053 ? 73  LYS A CG   1 
ATOM   719  C  CD   . LYS A 1 50  ? -8.23301  -4.29393  17.80639 1.000 15.70940 ? 73  LYS A CD   1 
ATOM   720  C  CE   . LYS A 1 50  ? -7.80647  -2.83358  17.46931 1.000 17.44355 ? 73  LYS A CE   1 
ATOM   721  N  NZ   . LYS A 1 50  ? -8.05882  -2.30231  16.10208 1.000 18.54678 ? 73  LYS A NZ   1 
ATOM   722  H  H    . LYS A 1 50  ? -5.64576  -6.99007  19.04224 1.000 17.64209 ? 73  LYS A H    1 
ATOM   723  H  HA   . LYS A 1 50  ? -6.72371  -6.01263  21.26010 1.000 19.59018 ? 73  LYS A HA   1 
ATOM   724  H  HB2  . LYS A 1 50  ? -7.93533  -6.77789  18.82036 1.000 19.66154 ? 73  LYS A HB2  1 
ATOM   725  H  HB3  . LYS A 1 50  ? -8.73866  -6.06275  19.99024 1.000 19.66154 ? 73  LYS A HB3  1 
ATOM   726  H  HG2  . LYS A 1 50  ? -7.55584  -4.11747  19.71648 1.000 22.78056 ? 73  LYS A HG2  1 
ATOM   727  H  HG3  . LYS A 1 50  ? -6.51154  -4.82598  18.75063 1.000 22.78056 ? 73  LYS A HG3  1 
ATOM   728  H  HD2  . LYS A 1 50  ? -8.04671  -4.86084  17.04166 1.000 18.83120 ? 73  LYS A HD2  1 
ATOM   729  H  HD3  . LYS A 1 50  ? -9.18229  -4.30670  18.00541 1.000 18.83120 ? 73  LYS A HD3  1 
ATOM   730  H  HE2  . LYS A 1 50  ? -8.27526  -2.24445  18.08091 1.000 20.91218 ? 73  LYS A HE2  1 
ATOM   731  H  HE3  . LYS A 1 50  ? -6.84953  -2.76864  17.61407 1.000 20.91218 ? 73  LYS A HE3  1 
ATOM   732  H  HZ1  . LYS A 1 50  ? -7.99338  -1.41472  16.10354 1.000 22.23606 ? 73  LYS A HZ1  1 
ATOM   733  H  HZ2  . LYS A 1 50  ? -7.46240  -2.63497  15.53137 1.000 22.23606 ? 73  LYS A HZ2  1 
ATOM   734  H  HZ3  . LYS A 1 50  ? -8.87552  -2.53127  15.83248 1.000 22.23606 ? 73  LYS A HZ3  1 
ATOM   735  N  N    . VAL A 1 51  ? -7.03910  -9.11984  20.89690 1.000 18.59420 ? 74  VAL A N    1 
ATOM   736  C  CA   . VAL A 1 51  ? -7.43520  -10.32042 21.62305 1.000 18.13098 ? 74  VAL A CA   1 
ATOM   737  C  C    . VAL A 1 51  ? -6.86548  -10.29495 23.03560 1.000 14.75476 ? 74  VAL A C    1 
ATOM   738  O  O    . VAL A 1 51  ? -7.56489  -10.60365 24.00914 1.000 15.02963 ? 74  VAL A O    1 
ATOM   739  C  CB   . VAL A 1 51  ? -6.99253  -11.58413 20.86358 1.000 18.03453 ? 74  VAL A CB   1 
ATOM   740  C  CG1  . VAL A 1 51  ? -7.17742  -12.80005 21.75523 1.000 17.77219 ? 74  VAL A CG1  1 
ATOM   741  C  CG2  . VAL A 1 51  ? -7.80846  -11.73595 19.56505 1.000 14.42249 ? 74  VAL A CG2  1 
ATOM   742  H  H    . VAL A 1 51  ? -6.57128  -9.26396  20.18981 1.000 22.29296 ? 74  VAL A H    1 
ATOM   743  H  HA   . VAL A 1 51  ? -8.40300  -10.33340 21.68698 1.000 21.73709 ? 74  VAL A HA   1 
ATOM   744  H  HB   . VAL A 1 51  ? -6.05550  -11.51200 20.62343 1.000 21.62136 ? 74  VAL A HB   1 
ATOM   745  H  HG11 . VAL A 1 51  ? -7.14771  -13.60040 21.20801 1.000 21.30655 ? 74  VAL A HG11 1 
ATOM   746  H  HG12 . VAL A 1 51  ? -6.46376  -12.82162 22.41184 1.000 21.30655 ? 74  VAL A HG12 1 
ATOM   747  H  HG13 . VAL A 1 51  ? -8.03608  -12.73646 22.20194 1.000 21.30655 ? 74  VAL A HG13 1 
ATOM   748  H  HG21 . VAL A 1 51  ? -7.46509  -12.49145 19.06284 1.000 17.28691 ? 74  VAL A HG21 1 
ATOM   749  H  HG22 . VAL A 1 51  ? -8.73939  -11.88570 19.79272 1.000 17.28691 ? 74  VAL A HG22 1 
ATOM   750  H  HG23 . VAL A 1 51  ? -7.72249  -10.92403 19.04131 1.000 17.28691 ? 74  VAL A HG23 1 
ATOM   751  N  N    A MET A 1 52  ? -5.57618  -9.95758  23.17054 0.435 13.78232 ? 75  MET A N    1 
ATOM   752  N  N    B MET A 1 52  ? -5.58421  -9.94174  23.16912 0.565 13.73798 ? 75  MET A N    1 
ATOM   753  C  CA   A MET A 1 52  ? -4.97075  -9.96114  24.50632 0.435 15.62105 ? 75  MET A CA   1 
ATOM   754  C  CA   B MET A 1 52  ? -4.97570  -9.96774  24.50050 0.565 15.60113 ? 75  MET A CA   1 
ATOM   755  C  C    A MET A 1 52  ? -5.61030  -8.90138  25.39010 0.435 17.81171 ? 75  MET A C    1 
ATOM   756  C  C    B MET A 1 52  ? -5.57916  -8.89261  25.39381 0.565 17.82526 ? 75  MET A C    1 
ATOM   757  O  O    A MET A 1 52  ? -5.85981  -9.14553  26.57760 0.435 17.71140 ? 75  MET A O    1 
ATOM   758  O  O    B MET A 1 52  ? -5.77023  -9.11663  26.59557 0.565 17.72047 ? 75  MET A O    1 
ATOM   759  C  CB   A MET A 1 52  ? -3.45480  -9.74978  24.43028 0.435 17.08740 ? 75  MET A CB   1 
ATOM   760  C  CB   B MET A 1 52  ? -3.45969  -9.80412  24.41660 0.565 17.06093 ? 75  MET A CB   1 
ATOM   761  C  CG   A MET A 1 52  ? -2.68296  -9.98475  25.76408 0.435 23.66720 ? 75  MET A CG   1 
ATOM   762  C  CG   B MET A 1 52  ? -2.72382  -10.26959 25.67524 0.565 24.79374 ? 75  MET A CG   1 
ATOM   763  S  SD   A MET A 1 52  ? -2.44722  -11.73305 26.28539 0.435 23.43461 ? 75  MET A SD   1 
ATOM   764  S  SD   B MET A 1 52  ? -2.55865  -12.08768 25.80951 0.565 20.75215 ? 75  MET A SD   1 
ATOM   765  C  CE   A MET A 1 52  ? -3.07875  -12.56307 24.84112 0.435 12.73597 ? 75  MET A CE   1 
ATOM   766  C  CE   B MET A 1 52  ? -1.17740  -12.36137 24.71581 0.565 15.01075 ? 75  MET A CE   1 
ATOM   767  H  H    A MET A 1 52  ? -5.05035  -9.73128  22.52875 0.435 16.51871 ? 75  MET A H    1 
ATOM   768  H  H    B MET A 1 52  ? -5.06537  -9.69281  22.53002 0.565 16.46549 ? 75  MET A H    1 
ATOM   769  H  HA   A MET A 1 52  ? -5.11252  -10.83792 24.89626 0.435 18.72518 ? 75  MET A HA   1 
ATOM   770  H  HA   B MET A 1 52  ? -5.14386  -10.84042 24.88916 0.565 18.70127 ? 75  MET A HA   1 
ATOM   771  H  HB2  A MET A 1 52  ? -3.09262  -10.36506 23.77366 0.435 20.48480 ? 75  MET A HB2  1 
ATOM   772  H  HB2  B MET A 1 52  ? -3.12974  -10.32697 23.66916 0.565 20.45303 ? 75  MET A HB2  1 
ATOM   773  H  HB3  A MET A 1 52  ? -3.28681  -8.83477  24.15562 0.435 20.48480 ? 75  MET A HB3  1 
ATOM   774  H  HB3  B MET A 1 52  ? -3.25352  -8.86591  24.28186 0.565 20.45303 ? 75  MET A HB3  1 
ATOM   775  H  HG2  A MET A 1 52  ? -1.79941  -9.59495  25.67302 0.435 28.38056 ? 75  MET A HG2  1 
ATOM   776  H  HG2  B MET A 1 52  ? -1.83044  -9.89177  25.67143 0.565 29.73240 ? 75  MET A HG2  1 
ATOM   777  H  HG3  A MET A 1 52  ? -3.16988  -9.54041  26.47568 0.435 28.38056 ? 75  MET A HG3  1 
ATOM   778  H  HG3  B MET A 1 52  ? -3.21186  -9.95947  26.45405 0.565 29.73240 ? 75  MET A HG3  1 
ATOM   779  H  HE1  A MET A 1 52  ? -2.99902  -13.52149 24.96753 0.435 15.26308 ? 75  MET A HE1  1 
ATOM   780  H  HE1  B MET A 1 52  ? -0.92938  -13.29855 24.74874 0.565 17.99282 ? 75  MET A HE1  1 
ATOM   781  H  HE2  A MET A 1 52  ? -4.01045  -12.32174 24.72029 0.435 15.26308 ? 75  MET A HE2  1 
ATOM   782  H  HE2  B MET A 1 52  ? -1.43668  -12.11935 23.81298 0.565 17.99282 ? 75  MET A HE2  1 
ATOM   783  H  HE3  A MET A 1 52  ? -2.56263  -12.28740 24.06748 0.435 15.26308 ? 75  MET A HE3  1 
ATOM   784  H  HE3  B MET A 1 52  ? -0.43220  -11.81165 25.00455 0.565 17.99282 ? 75  MET A HE3  1 
ATOM   785  N  N    . ALA A 1 53  ? -5.91480  -7.73114  24.82323 1.000 16.96442 ? 76  ALA A N    1 
ATOM   786  C  CA   . ALA A 1 53  ? -6.52004  -6.66766  25.61907 1.000 16.57017 ? 76  ALA A CA   1 
ATOM   787  C  C    . ALA A 1 53  ? -7.92528  -7.05042  26.07182 1.000 14.20410 ? 76  ALA A C    1 
ATOM   788  O  O    . ALA A 1 53  ? -8.28699  -6.85397  27.23705 1.000 15.16362 ? 76  ALA A O    1 
ATOM   789  C  CB   . ALA A 1 53  ? -6.55863  -5.35922  24.83763 1.000 15.82630 ? 76  ALA A CB   1 
ATOM   790  H  H    A ALA A 1 53  ? -5.78313  -7.53344  23.99668 0.435 20.33723 ? 76  ALA A H    1 
ATOM   791  H  H    B ALA A 1 53  ? -5.80362  -7.53963  23.99223 0.565 20.33723 ? 76  ALA A H    1 
ATOM   792  H  HA   . ALA A 1 53  ? -5.96735  -6.52940  26.40414 1.000 19.86412 ? 76  ALA A HA   1 
ATOM   793  H  HB1  . ALA A 1 53  ? -6.97370  -4.67565  25.38659 1.000 18.97147 ? 76  ALA A HB1  1 
ATOM   794  H  HB2  . ALA A 1 53  ? -5.65162  -5.09815  24.61387 1.000 18.97147 ? 76  ALA A HB2  1 
ATOM   795  H  HB3  . ALA A 1 53  ? -7.07456  -5.49073  24.02681 1.000 18.97147 ? 76  ALA A HB3  1 
ATOM   796  N  N    . ALA A 1 54  ? -8.74938  -7.56517  25.15539 1.000 16.50724 ? 77  ALA A N    1 
ATOM   797  C  CA   . ALA A 1 54  ? -10.07092 -8.05089  25.56049 1.000 17.37612 ? 77  ALA A CA   1 
ATOM   798  C  C    . ALA A 1 54  ? -9.96473  -9.16900  26.59565 1.000 18.22227 ? 77  ALA A C    1 
ATOM   799  O  O    . ALA A 1 54  ? -10.76534 -9.24431  27.53587 1.000 17.31119 ? 77  ALA A O    1 
ATOM   800  C  CB   . ALA A 1 54  ? -10.86416 -8.54831  24.34281 1.000 15.87479 ? 77  ALA A CB   1 
ATOM   801  H  H    . ALA A 1 54  ? -8.57351  -7.64266  24.31714 1.000 19.78861 ? 77  ALA A H    1 
ATOM   802  H  HA   . ALA A 1 54  ? -10.55203 -7.30674  25.95504 1.000 20.83126 ? 77  ALA A HA   1 
ATOM   803  H  HB1  . ALA A 1 54  ? -11.73128 -8.86634  24.63924 1.000 19.02966 ? 77  ALA A HB1  1 
ATOM   804  H  HB2  . ALA A 1 54  ? -10.97671 -7.81481  23.71814 1.000 19.02966 ? 77  ALA A HB2  1 
ATOM   805  H  HB3  . ALA A 1 54  ? -10.37376 -9.27057  23.92002 1.000 19.02966 ? 77  ALA A HB3  1 
ATOM   806  N  N    . ALA A 1 55  ? -8.99839  -10.07050 26.42569 1.000 16.28600 ? 78  ALA A N    1 
ATOM   807  C  CA   . ALA A 1 55  ? -8.82788  -11.15443 27.37510 1.000 17.22399 ? 78  ALA A CA   1 
ATOM   808  C  C    . ALA A 1 55  ? -8.42610  -10.62319 28.74821 1.000 14.47023 ? 78  ALA A C    1 
ATOM   809  O  O    . ALA A 1 55  ? -8.84049  -11.15807 29.78703 1.000 16.39600 ? 78  ALA A O    1 
ATOM   810  C  CB   . ALA A 1 55  ? -7.78488  -12.12534 26.84236 1.000 17.10381 ? 78  ALA A CB   1 
ATOM   811  H  H    . ALA A 1 55  ? -8.43648  -10.07327 25.77465 1.000 19.52312 ? 78  ALA A H    1 
ATOM   812  H  HA   . ALA A 1 55  ? -9.66592  -11.63175 27.47877 1.000 20.64871 ? 78  ALA A HA   1 
ATOM   813  H  HB1  . ALA A 1 55  ? -7.67138  -12.84786 27.47953 1.000 20.50449 ? 78  ALA A HB1  1 
ATOM   814  H  HB2  . ALA A 1 55  ? -8.08815  -12.47915 25.99162 1.000 20.50449 ? 78  ALA A HB2  1 
ATOM   815  H  HB3  . ALA A 1 55  ? -6.94556  -11.65367 26.72414 1.000 20.50449 ? 78  ALA A HB3  1 
ATOM   816  N  N    . ALA A 1 56  ? -7.59046  -9.59019  28.77126 1.000 16.29912 ? 79  ALA A N    1 
ATOM   817  C  CA   . ALA A 1 56  ? -7.21630  -8.97475  30.05233 1.000 18.17193 ? 79  ALA A CA   1 
ATOM   818  C  C    . ALA A 1 56  ? -8.43346  -8.42429  30.79275 1.000 16.42017 ? 79  ALA A C    1 
ATOM   819  O  O    . ALA A 1 56  ? -8.53836  -8.57675  32.01484 1.000 17.78823 ? 79  ALA A O    1 
ATOM   820  C  CB   . ALA A 1 56  ? -6.17859  -7.88072  29.80999 1.000 20.70849 ? 79  ALA A CB   1 
ATOM   821  H  H    . ALA A 1 56  ? -7.23047  -9.22976  28.07836 1.000 19.53886 ? 79  ALA A H    1 
ATOM   822  H  HA   . ALA A 1 56  ? -6.81701  -9.65041  30.62236 1.000 21.78623 ? 79  ALA A HA   1 
ATOM   823  H  HB1  . ALA A 1 56  ? -5.95873  -7.46092  30.65635 1.000 24.83010 ? 79  ALA A HB1  1 
ATOM   824  H  HB2  . ALA A 1 56  ? -5.38390  -8.27953  29.42227 1.000 24.83010 ? 79  ALA A HB2  1 
ATOM   825  H  HB3  . ALA A 1 56  ? -6.54940  -7.22304  29.20100 1.000 24.83010 ? 79  ALA A HB3  1 
ATOM   826  N  N    . VAL A 1 57  ? -9.34336  -7.75314  30.07261 1.000 18.97274 ? 80  VAL A N    1 
ATOM   827  C  CA   . VAL A 1 57  ? -10.56815 -7.23466  30.68269 1.000 18.60178 ? 80  VAL A CA   1 
ATOM   828  C  C    . VAL A 1 57  ? -11.43400 -8.38189  31.16822 1.000 16.68802 ? 80  VAL A C    1 
ATOM   829  O  O    . VAL A 1 57  ? -11.93478 -8.37515  32.29355 1.000 17.68727 ? 80  VAL A O    1 
ATOM   830  C  CB   . VAL A 1 57  ? -11.33115 -6.33813  29.69124 1.000 21.20737 ? 80  VAL A CB   1 
ATOM   831  C  CG1  . VAL A 1 57  ? -12.68573 -5.97679  30.23206 1.000 20.57509 ? 80  VAL A CG1  1 
ATOM   832  C  CG2  . VAL A 1 57  ? -10.52504 -5.07366  29.42915 1.000 23.66743 ? 80  VAL A CG2  1 
ATOM   833  H  H    . VAL A 1 57  ? -9.27309  -7.58652  29.23183 1.000 22.74721 ? 80  VAL A H    1 
ATOM   834  H  HA   . VAL A 1 57  ? -10.32397 -6.69125  31.44819 1.000 22.30206 ? 80  VAL A HA   1 
ATOM   835  H  HB   . VAL A 1 57  ? -11.45770 -6.82032  28.85914 1.000 25.42877 ? 80  VAL A HB   1 
ATOM   836  H  HG11 . VAL A 1 57  ? -13.04094 -5.23198  29.72218 1.000 24.67003 ? 80  VAL A HG11 1 
ATOM   837  H  HG12 . VAL A 1 57  ? -13.27349 -6.74406  30.14999 1.000 24.67003 ? 80  VAL A HG12 1 
ATOM   838  H  HG13 . VAL A 1 57  ? -12.59682 -5.72652  31.16499 1.000 24.67003 ? 80  VAL A HG13 1 
ATOM   839  H  HG21 . VAL A 1 57  ? -11.02304 -4.50125  28.82479 1.000 28.38084 ? 80  VAL A HG21 1 
ATOM   840  H  HG22 . VAL A 1 57  ? -10.37459 -4.61499  30.27051 1.000 28.38084 ? 80  VAL A HG22 1 
ATOM   841  H  HG23 . VAL A 1 57  ? -9.67580  -5.31780  29.02903 1.000 28.38084 ? 80  VAL A HG23 1 
ATOM   842  N  N    . LEU A 1 58  ? -11.59733 -9.40299  30.33017 1.000 18.84596 ? 81  LEU A N    1 
ATOM   843  C  CA   . LEU A 1 58  ? -12.36392 -10.57354 30.74866 1.000 16.81128 ? 81  LEU A CA   1 
ATOM   844  C  C    . LEU A 1 58  ? -11.79760 -11.20139 32.01876 1.000 17.63406 ? 81  LEU A C    1 
ATOM   845  O  O    . LEU A 1 58  ? -12.55891 -11.57160 32.92404 1.000 19.61001 ? 81  LEU A O    1 
ATOM   846  C  CB   . LEU A 1 58  ? -12.41067 -11.58749 29.61855 1.000 18.76708 ? 81  LEU A CB   1 
ATOM   847  C  CG   . LEU A 1 58  ? -13.45403 -11.33434 28.52343 1.000 17.76843 ? 81  LEU A CG   1 
ATOM   848  C  CD1  . LEU A 1 58  ? -13.13005 -12.24138 27.35494 1.000 18.85227 ? 81  LEU A CD1  1 
ATOM   849  C  CD2  . LEU A 1 58  ? -14.91210 -11.55158 28.99149 1.000 21.63506 ? 81  LEU A CD2  1 
ATOM   850  H  H    . LEU A 1 58  ? -11.28190 -9.44305  29.53111 1.000 22.59507 ? 81  LEU A H    1 
ATOM   851  H  HA   . LEU A 1 58  ? -13.27188 -10.29500 30.94598 1.000 20.15345 ? 81  LEU A HA   1 
ATOM   852  H  HB2  . LEU A 1 58  ? -11.54139 -11.59971 29.18832 1.000 22.50041 ? 81  LEU A HB2  1 
ATOM   853  H  HB3  . LEU A 1 58  ? -12.60339 -12.45746 30.00185 1.000 22.50041 ? 81  LEU A HB3  1 
ATOM   854  H  HG   . LEU A 1 58  ? -13.41127 -10.40080 28.26350 1.000 21.30204 ? 81  LEU A HG   1 
ATOM   855  H  HD11 . LEU A 1 58  ? -13.77922 -12.09210 26.64981 1.000 22.60264 ? 81  LEU A HD11 1 
ATOM   856  H  HD12 . LEU A 1 58  ? -12.23859 -12.03530 27.03288 1.000 22.60264 ? 81  LEU A HD12 1 
ATOM   857  H  HD13 . LEU A 1 58  ? -13.16966 -13.16423 27.65105 1.000 22.60264 ? 81  LEU A HD13 1 
ATOM   858  H  HD21 . LEU A 1 58  ? -15.50492 -11.46461 28.22867 1.000 25.94199 ? 81  LEU A HD21 1 
ATOM   859  H  HD22 . LEU A 1 58  ? -14.99225 -12.43974 29.37314 1.000 25.94199 ? 81  LEU A HD22 1 
ATOM   860  H  HD23 . LEU A 1 58  ? -15.13224 -10.88346 29.65936 1.000 25.94199 ? 81  LEU A HD23 1 
ATOM   861  N  N    B LYS A 1 59  ? -10.47141 -11.33159 32.10715 0.542 18.65182 ? 82  LYS A N    1 
ATOM   862  N  N    C LYS A 1 59  ? -10.47083 -11.32975 32.10775 0.458 18.64670 ? 82  LYS A N    1 
ATOM   863  C  CA   B LYS A 1 59  ? -9.85968  -11.89332 33.31513 0.542 21.75167 ? 82  LYS A CA   1 
ATOM   864  C  CA   C LYS A 1 59  ? -9.85941  -11.89345 33.31368 0.458 21.75508 ? 82  LYS A CA   1 
ATOM   865  C  C    B LYS A 1 59  ? -10.16945 -11.03400 34.53368 0.542 22.36509 ? 82  LYS A C    1 
ATOM   866  C  C    C LYS A 1 59  ? -10.16722 -11.03451 34.53368 0.458 22.35848 ? 82  LYS A C    1 
ATOM   867  O  O    B LYS A 1 59  ? -10.53892 -11.54013 35.60413 0.542 21.63392 ? 82  LYS A O    1 
ATOM   868  O  O    C LYS A 1 59  ? -10.53620 -11.54187 35.60366 0.458 21.65860 ? 82  LYS A O    1 
ATOM   869  C  CB   B LYS A 1 59  ? -8.34872  -12.01129 33.11817 0.542 19.86315 ? 82  LYS A CB   1 
ATOM   870  C  CB   C LYS A 1 59  ? -8.34859  -12.01400 33.11717 0.458 19.88753 ? 82  LYS A CB   1 
ATOM   871  C  CG   B LYS A 1 59  ? -7.57022  -12.44322 34.35993 0.542 23.56782 ? 82  LYS A CG   1 
ATOM   872  C  CG   C LYS A 1 59  ? -7.58218  -12.50540 34.34255 0.458 23.59628 ? 82  LYS A CG   1 
ATOM   873  C  CD   B LYS A 1 59  ? -7.87623  -13.87828 34.74302 0.542 29.48846 ? 82  LYS A CD   1 
ATOM   874  C  CD   C LYS A 1 59  ? -7.93791  -13.94090 34.67749 0.458 29.47499 ? 82  LYS A CD   1 
ATOM   875  C  CE   B LYS A 1 59  ? -7.04087  -14.30504 35.94182 0.542 37.63577 ? 82  LYS A CE   1 
ATOM   876  C  CE   C LYS A 1 59  ? -7.18928  -14.41123 35.91350 0.458 37.70536 ? 82  LYS A CE   1 
ATOM   877  N  NZ   B LYS A 1 59  ? -7.36851  -15.68395 36.41542 0.542 38.90789 ? 82  LYS A NZ   1 
ATOM   878  N  NZ   C LYS A 1 59  ? -5.71564  -14.47585 35.68696 0.458 42.63036 ? 82  LYS A NZ   1 
ATOM   879  H  H    B LYS A 1 59  ? -9.91245  -11.10669 31.49348 0.542 22.36210 ? 82  LYS A H    1 
ATOM   880  H  H    C LYS A 1 59  ? -9.91182  -11.10225 31.49510 0.458 22.35596 ? 82  LYS A H    1 
ATOM   881  H  HA   B LYS A 1 59  ? -10.22112 -12.78017 33.46925 0.542 26.08193 ? 82  LYS A HA   1 
ATOM   882  H  HA   C LYS A 1 59  ? -10.22217 -12.78006 33.46607 0.458 26.08602 ? 82  LYS A HA   1 
ATOM   883  H  HB2  B LYS A 1 59  ? -8.17945  -12.66841 32.42503 0.542 23.81570 ? 82  LYS A HB2  1 
ATOM   884  H  HB2  C LYS A 1 59  ? -8.18082  -12.64161 32.39685 0.458 23.84496 ? 82  LYS A HB2  1 
ATOM   885  H  HB3  B LYS A 1 59  ? -8.00573  -11.14583 32.84572 0.542 23.81570 ? 82  LYS A HB3  1 
ATOM   886  H  HB3  C LYS A 1 59  ? -7.99760  -11.14022 32.88435 0.458 23.84496 ? 82  LYS A HB3  1 
ATOM   887  H  HG2  B LYS A 1 59  ? -6.61919  -12.37211 34.18277 0.542 28.26131 ? 82  LYS A HG2  1 
ATOM   888  H  HG2  C LYS A 1 59  ? -6.62950  -12.46009 34.16580 0.458 28.29545 ? 82  LYS A HG2  1 
ATOM   889  H  HG3  B LYS A 1 59  ? -7.81255  -11.87144 35.10508 0.542 28.26131 ? 82  LYS A HG3  1 
ATOM   890  H  HG3  C LYS A 1 59  ? -7.80484  -11.94953 35.10565 0.458 28.29545 ? 82  LYS A HG3  1 
ATOM   891  H  HD2  B LYS A 1 59  ? -8.81423  -13.95863 34.97669 0.542 35.36607 ? 82  LYS A HD2  1 
ATOM   892  H  HD2  C LYS A 1 59  ? -8.88994  -14.00611 34.85149 0.458 35.34991 ? 82  LYS A HD2  1 
ATOM   893  H  HD3  B LYS A 1 59  ? -7.66848  -14.46412 33.99835 0.542 35.36607 ? 82  LYS A HD3  1 
ATOM   894  H  HD3  C LYS A 1 59  ? -7.69630  -14.51586 33.93455 0.458 35.34991 ? 82  LYS A HD3  1 
ATOM   895  H  HE2  B LYS A 1 59  ? -6.10282  -14.28806 35.69550 0.542 45.14284 ? 82  LYS A HE2  1 
ATOM   896  H  HE2  C LYS A 1 59  ? -7.35648  -13.79297 36.64198 0.458 45.22635 ? 82  LYS A HE2  1 
ATOM   897  H  HE3  B LYS A 1 59  ? -7.20263  -13.69044 36.67463 0.542 45.14284 ? 82  LYS A HE3  1 
ATOM   898  H  HE3  C LYS A 1 59  ? -7.49748  -15.29887 36.15435 0.458 45.22635 ? 82  LYS A HE3  1 
ATOM   899  H  HZ1  B LYS A 1 59  ? -8.22550  -15.72920 36.65128 0.542 46.66939 ? 82  LYS A HZ1  1 
ATOM   900  H  HZ1  C LYS A 1 59  ? -5.40435  -13.66906 35.47653 0.458 51.13635 ? 82  LYS A HZ1  1 
ATOM   901  H  HZ2  B LYS A 1 59  ? -7.21619  -16.27309 35.76595 0.542 46.66939 ? 82  LYS A HZ2  1 
ATOM   902  H  HZ2  C LYS A 1 59  ? -5.30646  -14.75999 36.42448 0.458 51.13635 ? 82  LYS A HZ2  1 
ATOM   903  H  HZ3  B LYS A 1 59  ? -6.86407  -15.89223 37.11846 0.542 46.66939 ? 82  LYS A HZ3  1 
ATOM   904  H  HZ3  C LYS A 1 59  ? -5.53437  -15.03805 35.02125 0.458 51.13635 ? 82  LYS A HZ3  1 
ATOM   905  N  N    . LYS A 1 60  ? -9.98727  -9.72547  34.39907 1.000 19.17629 ? 83  LYS A N    1 
ATOM   906  C  CA   . LYS A 1 60  ? -10.32767 -8.79609  35.47832 1.000 21.99094 ? 83  LYS A CA   1 
ATOM   907  C  C    . LYS A 1 60  ? -11.77196 -8.96801  35.91476 1.000 22.88373 ? 83  LYS A C    1 
ATOM   908  O  O    . LYS A 1 60  ? -12.08772 -8.86509  37.10369 1.000 27.43782 ? 83  LYS A O    1 
ATOM   909  C  CB   . LYS A 1 60  ? -10.06643 -7.37433  34.98287 1.000 20.61890 ? 83  LYS A CB   1 
ATOM   910  C  CG   . LYS A 1 60  ? -10.17404 -6.25769  36.03110 1.000 27.75313 ? 83  LYS A CG   1 
ATOM   911  C  CD   . LYS A 1 60  ? -9.79869  -4.89759  35.39959 1.000 30.51674 ? 83  LYS A CD   1 
ATOM   912  C  CE   . LYS A 1 60  ? -9.75887  -3.74283  36.42293 1.000 41.42329 ? 83  LYS A CE   1 
ATOM   913  N  NZ   . LYS A 1 60  ? -11.11672 -3.28414  36.84044 1.000 44.35471 ? 83  LYS A NZ   1 
ATOM   914  H  H    . LYS A 1 60  ? -9.66862  -9.34903  33.69455 1.000 22.99146 ? 83  LYS A H    1 
ATOM   915  H  HA   . LYS A 1 60  ? -9.77328  -8.96368  36.25643 1.000 26.36905 ? 83  LYS A HA   1 
ATOM   916  H  HB2  . LYS A 1 60  ? -9.16663  -7.34099  34.62210 1.000 24.72260 ? 83  LYS A HB2  1 
ATOM   917  H  HB3  . LYS A 1 60  ? -10.71088 -7.17435  34.28603 1.000 24.72260 ? 83  LYS A HB3  1 
ATOM   918  H  HG2  . LYS A 1 60  ? -11.08474 -6.20622  36.36107 1.000 33.28367 ? 83  LYS A HG2  1 
ATOM   919  H  HG3  . LYS A 1 60  ? -9.56523  -6.43833  36.76433 1.000 33.28367 ? 83  LYS A HG3  1 
ATOM   920  H  HD2  . LYS A 1 60  ? -8.91897  -4.96932  34.99727 1.000 36.60001 ? 83  LYS A HD2  1 
ATOM   921  H  HD3  . LYS A 1 60  ? -10.45584 -4.67278  34.72245 1.000 36.60001 ? 83  LYS A HD3  1 
ATOM   922  H  HE2  . LYS A 1 60  ? -9.28759  -4.04117  37.21652 1.000 49.68786 ? 83  LYS A HE2  1 
ATOM   923  H  HE3  . LYS A 1 60  ? -9.29714  -2.98703  36.02737 1.000 49.68786 ? 83  LYS A HE3  1 
ATOM   924  H  HZ1  . LYS A 1 60  ? -11.37154 -2.59307  36.34085 1.000 53.20557 ? 83  LYS A HZ1  1 
ATOM   925  H  HZ2  . LYS A 1 60  ? -11.70495 -3.94464  36.74137 1.000 53.20557 ? 83  LYS A HZ2  1 
ATOM   926  H  HZ3  . LYS A 1 60  ? -11.10430 -3.03411  37.69451 1.000 53.20557 ? 83  LYS A HZ3  1 
ATOM   927  N  N    . SER A 1 61  ? -12.66557 -9.25695  34.96221 1.000 21.69518 ? 84  SER A N    1 
ATOM   928  C  CA   . SER A 1 61  ? -14.08165 -9.44448  35.26821 1.000 21.00662 ? 84  SER A CA   1 
ATOM   929  C  C    . SER A 1 61  ? -14.35867 -10.65613 36.15100 1.000 25.89666 ? 84  SER A C    1 
ATOM   930  O  O    . SER A 1 61  ? -15.40895 -10.70157 36.79467 1.000 26.03158 ? 84  SER A O    1 
ATOM   931  C  CB   . SER A 1 61  ? -14.88707 -9.57495  33.97019 1.000 21.04390 ? 84  SER A CB   1 
ATOM   932  O  OG   . SER A 1 61  ? -14.84951 -10.87389 33.37748 1.000 22.78795 ? 84  SER A OG   1 
ATOM   933  H  H    . SER A 1 61  ? -12.47437 -9.34958  34.12887 1.000 26.01414 ? 84  SER A H    1 
ATOM   934  H  HA   . SER A 1 61  ? -14.38320 -8.65785  35.74903 1.000 25.18787 ? 84  SER A HA   1 
ATOM   935  H  HB2  . SER A 1 61  ? -15.81236 -9.36079  34.16737 1.000 25.23260 ? 84  SER A HB2  1 
ATOM   936  H  HB3  . SER A 1 61  ? -14.52922 -8.94114  33.32900 1.000 25.23260 ? 84  SER A HB3  1 
ATOM   937  H  HG   . SER A 1 61  ? -14.05290 -11.11787 33.27035 1.000 27.32546 ? 84  SER A HG   1 
ATOM   938  N  N    . GLU A 1 62  ? -13.46612 -11.64544 36.18948 1.000 23.00681 ? 85  GLU A N    1 
ATOM   939  C  CA   . GLU A 1 62  ? -13.70130 -12.81605 37.03404 1.000 25.03124 ? 85  GLU A CA   1 
ATOM   940  C  C    . GLU A 1 62  ? -13.83284 -12.42395 38.49318 1.000 33.23329 ? 85  GLU A C    1 
ATOM   941  O  O    . GLU A 1 62  ? -14.57030 -13.06549 39.24591 1.000 36.68377 ? 85  GLU A O    1 
ATOM   942  C  CB   . GLU A 1 62  ? -12.57113 -13.84032 36.85482 1.000 22.95382 ? 85  GLU A CB   1 
ATOM   943  C  CG   . GLU A 1 62  ? -12.58302 -14.41223 35.45130 1.000 25.27159 ? 85  GLU A CG   1 
ATOM   944  C  CD   . GLU A 1 62  ? -11.42604 -15.33521 35.15007 1.000 27.84318 ? 85  GLU A CD   1 
ATOM   945  O  OE1  . GLU A 1 62  ? -10.72835 -15.77059 36.09132 1.000 34.62772 ? 85  GLU A OE1  1 
ATOM   946  O  OE2  . GLU A 1 62  ? -11.24104 -15.62123 33.94423 1.000 26.06547 ? 85  GLU A OE2  1 
ATOM   947  H  H    . GLU A 1 62  ? -12.73007 -11.66398 35.74509 1.000 27.58809 ? 85  GLU A H    1 
ATOM   948  H  HA   . GLU A 1 62  ? -14.52876 -13.23985 36.75725 1.000 30.01741 ? 85  GLU A HA   1 
ATOM   949  H  HB2  . GLU A 1 62  ? -11.71593 -13.40790 37.00496 1.000 27.52450 ? 85  GLU A HB2  1 
ATOM   950  H  HB3  . GLU A 1 62  ? -12.69054 -14.56740 37.48569 1.000 27.52450 ? 85  GLU A HB3  1 
ATOM   951  H  HG2  . GLU A 1 62  ? -13.40184 -14.91759 35.32866 1.000 30.30583 ? 85  GLU A HG2  1 
ATOM   952  H  HG3  . GLU A 1 62  ? -12.54729 -13.67935 34.81686 1.000 30.30583 ? 85  GLU A HG3  1 
ATOM   953  N  N    A SER A 1 63  ? -13.13780 -11.37888 38.91416 0.728 30.50059 ? 86  SER A N    1 
ATOM   954  N  N    B SER A 1 63  ? -13.14423 -11.36596 38.90938 0.272 30.57315 ? 86  SER A N    1 
ATOM   955  C  CA   A SER A 1 63  ? -13.22040 -10.91744 40.29215 0.728 35.53883 ? 86  SER A CA   1 
ATOM   956  C  CA   B SER A 1 63  ? -13.19664 -10.89394 40.28595 0.272 35.61441 ? 86  SER A CA   1 
ATOM   957  C  C    A SER A 1 63  ? -14.04417 -9.64672  40.45237 0.728 37.41725 ? 86  SER A C    1 
ATOM   958  C  C    B SER A 1 63  ? -14.07139 -9.65942  40.45905 0.272 37.44852 ? 86  SER A C    1 
ATOM   959  O  O    A SER A 1 63  ? -14.14213 -9.13645  41.57425 0.728 35.22688 ? 86  SER A O    1 
ATOM   960  O  O    B SER A 1 63  ? -14.22695 -9.18251  41.58793 0.272 35.39306 ? 86  SER A O    1 
ATOM   961  C  CB   A SER A 1 63  ? -11.80993 -10.68660 40.85118 0.728 32.93016 ? 86  SER A CB   1 
ATOM   962  C  CB   B SER A 1 63  ? -11.78080 -10.58734 40.78706 0.272 33.09017 ? 86  SER A CB   1 
ATOM   963  O  OG   A SER A 1 63  ? -11.01089 -9.96096  39.92409 0.728 32.87566 ? 86  SER A OG   1 
ATOM   964  O  OG   B SER A 1 63  ? -10.89029 -11.64956 40.48495 0.272 30.67020 ? 86  SER A OG   1 
ATOM   965  H  H    A SER A 1 63  ? -12.60804 -10.91728 38.41829 0.728 36.58062 ? 86  SER A H    1 
ATOM   966  H  H    B SER A 1 63  ? -12.63075 -10.89756 38.40288 0.272 36.66770 ? 86  SER A H    1 
ATOM   967  H  HA   A SER A 1 63  ? -13.64692 -11.60986 40.82086 0.728 42.62652 ? 86  SER A HA   1 
ATOM   968  H  HA   B SER A 1 63  ? -13.56798 -11.59940 40.83852 0.272 42.71722 ? 86  SER A HA   1 
ATOM   969  H  HB2  A SER A 1 63  ? -11.87598 -10.17983 41.67563 0.728 39.49611 ? 86  SER A HB2  1 
ATOM   970  H  HB2  B SER A 1 63  ? -11.46300 -9.77827  40.35656 0.272 39.68813 ? 86  SER A HB2  1 
ATOM   971  H  HB3  A SER A 1 63  ? -11.39350 -11.54578 41.02233 0.728 39.49611 ? 86  SER A HB3  1 
ATOM   972  H  HB3  B SER A 1 63  ? -11.80744 -10.46296 41.74868 0.272 39.68813 ? 86  SER A HB3  1 
ATOM   973  H  HG   A SER A 1 63  ? -11.31744 -9.18504  39.82627 0.728 39.43071 ? 86  SER A HG   1 
ATOM   974  H  HG   B SER A 1 63  ? -10.85734 -11.76936 39.65419 0.272 36.78416 ? 86  SER A HG   1 
ATOM   975  N  N    . GLU A 1 64  ? -14.65811 -9.14595  39.37903 1.000 39.31353 ? 87  GLU A N    1 
ATOM   976  C  CA   . GLU A 1 64  ? -15.46185 -7.92371  39.42619 1.000 38.35118 ? 87  GLU A CA   1 
ATOM   977  C  C    . GLU A 1 64  ? -16.70032 -8.14108  38.56591 1.000 36.50873 ? 87  GLU A C    1 
ATOM   978  O  O    . GLU A 1 64  ? -16.71550 -7.79478  37.37498 1.000 37.77091 ? 87  GLU A O    1 
ATOM   979  C  CB   . GLU A 1 64  ? -14.67699 -6.70869  38.93567 1.000 32.30031 ? 87  GLU A CB   1 
ATOM   980  C  CG   . GLU A 1 64  ? -13.36246 -6.48245  39.62804 1.000 43.12445 ? 87  GLU A CG   1 
ATOM   981  C  CD   . GLU A 1 64  ? -12.56209 -5.34810  38.99817 1.000 52.08215 ? 87  GLU A CD   1 
ATOM   982  O  OE1  . GLU A 1 64  ? -13.17246 -4.41689  38.42605 1.000 43.32529 ? 87  GLU A OE1  1 
ATOM   983  O  OE2  . GLU A 1 64  ? -11.31867 -5.38795  39.07942 1.000 50.16384 ? 87  GLU A OE2  1 
ATOM   984  H  H    . GLU A 1 64  ? -14.62427 -9.50183  38.59685 1.000 47.15615 ? 87  GLU A H    1 
ATOM   985  H  HA   . GLU A 1 64  ? -15.73346 -7.75539  40.34205 1.000 46.00134 ? 87  GLU A HA   1 
ATOM   986  H  HB2  . GLU A 1 64  ? -14.49225 -6.82336  37.99035 1.000 38.74029 ? 87  GLU A HB2  1 
ATOM   987  H  HB3  . GLU A 1 64  ? -15.21913 -5.91633  39.07403 1.000 38.74029 ? 87  GLU A HB3  1 
ATOM   988  H  HG2  . GLU A 1 64  ? -13.52756 -6.25556  40.55656 1.000 51.72926 ? 87  GLU A HG2  1 
ATOM   989  H  HG3  . GLU A 1 64  ? -12.83148 -7.29240  39.57379 1.000 51.72926 ? 87  GLU A HG3  1 
ATOM   990  N  N    . PRO A 1 65  ? -17.77524 -8.68018  39.14953 1.000 43.10329 ? 88  PRO A N    1 
ATOM   991  C  CA   . PRO A 1 65  ? -18.91922 -9.11384  38.32405 1.000 53.35396 ? 88  PRO A CA   1 
ATOM   992  C  C    . PRO A 1 65  ? -19.64362 -7.98937  37.59978 1.000 48.22255 ? 88  PRO A C    1 
ATOM   993  O  O    . PRO A 1 65  ? -20.27413 -8.24494  36.56541 1.000 53.47295 ? 88  PRO A O    1 
ATOM   994  C  CB   . PRO A 1 65  ? -19.85437 -9.78720  39.33616 1.000 56.04254 ? 88  PRO A CB   1 
ATOM   995  C  CG   . PRO A 1 65  ? -19.06192 -9.92719  40.61393 1.000 54.32599 ? 88  PRO A CG   1 
ATOM   996  C  CD   . PRO A 1 65  ? -18.03234 -8.84570  40.58652 1.000 56.05409 ? 88  PRO A CD   1 
ATOM   997  H  HA   . PRO A 1 65  ? -18.60157 -9.75887  37.67295 1.000 64.00467 ? 88  PRO A HA   1 
ATOM   998  H  HB2  . PRO A 1 65  ? -20.63615 -9.23052  39.47698 1.000 67.23096 ? 88  PRO A HB2  1 
ATOM   999  H  HB3  . PRO A 1 65  ? -20.12259 -10.65748 39.00214 1.000 67.23096 ? 88  PRO A HB3  1 
ATOM   1000 H  HG2  . PRO A 1 65  ? -19.65166 -9.81903  41.37643 1.000 65.17111 ? 88  PRO A HG2  1 
ATOM   1001 H  HG3  . PRO A 1 65  ? -18.64040 -10.80037 40.64176 1.000 65.17111 ? 88  PRO A HG3  1 
ATOM   1002 H  HD2  . PRO A 1 65  ? -18.37844 -8.02664  40.97414 1.000 67.24483 ? 88  PRO A HD2  1 
ATOM   1003 H  HD3  . PRO A 1 65  ? -17.22790 -9.11993  41.05405 1.000 67.24483 ? 88  PRO A HD3  1 
ATOM   1004 N  N    . ASN A 1 66  ? -19.61582 -6.76668  38.11769 1.000 45.97656 ? 89  ASN A N    1 
ATOM   1005 C  CA   . ASN A 1 66  ? -20.23164 -5.67032  37.38712 1.000 54.73155 ? 89  ASN A CA   1 
ATOM   1006 C  C    . ASN A 1 66  ? -19.37258 -5.18254  36.23361 1.000 34.21676 ? 89  ASN A C    1 
ATOM   1007 O  O    . ASN A 1 66  ? -19.82941 -4.33079  35.46236 1.000 34.57358 ? 89  ASN A O    1 
ATOM   1008 C  CB   . ASN A 1 66  ? -20.50387 -4.48376  38.31588 1.000 59.43177 ? 89  ASN A CB   1 
ATOM   1009 C  CG   . ASN A 1 66  ? -21.61950 -4.75526  39.29542 1.000 62.53925 ? 89  ASN A CG   1 
ATOM   1010 O  OD1  . ASN A 1 66  ? -22.55691 -5.49112  38.99345 1.000 77.34023 ? 89  ASN A OD1  1 
ATOM   1011 N  ND2  . ASN A 1 66  ? -21.52796 -4.15661  40.48071 1.000 74.87808 ? 89  ASN A ND2  1 
ATOM   1012 H  H    . ASN A 1 66  ? -19.25628 -6.55381  38.86937 1.000 55.15179 ? 89  ASN A H    1 
ATOM   1013 H  HA   . ASN A 1 66  ? -21.08127 -5.98444  37.04021 1.000 65.65778 ? 89  ASN A HA   1 
ATOM   1014 H  HB2  . ASN A 1 66  ? -19.70035 -4.28788  38.82273 1.000 71.29804 ? 89  ASN A HB2  1 
ATOM   1015 H  HB3  . ASN A 1 66  ? -20.75455 -3.71435  37.78102 1.000 71.29804 ? 89  ASN A HB3  1 
ATOM   1016 H  HD21 . ASN A 1 66  ? -22.13911 -4.27994  41.07307 1.000 89.83361 ? 89  ASN A HD21 1 
ATOM   1017 H  HD22 . ASN A 1 66  ? -20.85768 -3.64649  40.65417 1.000 89.83361 ? 89  ASN A HD22 1 
ATOM   1018 N  N    . LEU A 1 67  ? -18.14435 -5.68982  36.10030 1.000 27.96052 ? 90  LEU A N    1 
ATOM   1019 C  CA   . LEU A 1 67  ? -17.15337 -4.98064  35.30351 1.000 25.15827 ? 90  LEU A CA   1 
ATOM   1020 C  C    . LEU A 1 67  ? -17.62485 -4.79043  33.86614 1.000 22.53837 ? 90  LEU A C    1 
ATOM   1021 O  O    . LEU A 1 67  ? -17.52585 -3.69023  33.31114 1.000 23.26656 ? 90  LEU A O    1 
ATOM   1022 C  CB   . LEU A 1 67  ? -15.80539 -5.70530  35.33956 1.000 25.14470 ? 90  LEU A CB   1 
ATOM   1023 C  CG   . LEU A 1 67  ? -14.65492 -4.93990  34.67679 1.000 27.55364 ? 90  LEU A CG   1 
ATOM   1024 C  CD1  . LEU A 1 67  ? -14.38001 -3.60466  35.38052 1.000 40.38663 ? 90  LEU A CD1  1 
ATOM   1025 C  CD2  . LEU A 1 67  ? -13.37777 -5.80416  34.62004 1.000 29.30190 ? 90  LEU A CD2  1 
ATOM   1026 H  H    . LEU A 1 67  ? -17.87011 -6.42446  36.45343 1.000 33.53254 ? 90  LEU A H    1 
ATOM   1027 H  HA   . LEU A 1 67  ? -17.02559 -4.10323  35.69687 1.000 30.16984 ? 90  LEU A HA   1 
ATOM   1028 H  HB2  . LEU A 1 67  ? -15.56174 -5.85732  36.26608 1.000 30.15356 ? 90  LEU A HB2  1 
ATOM   1029 H  HB3  . LEU A 1 67  ? -15.89867 -6.55314  34.87765 1.000 30.15356 ? 90  LEU A HB3  1 
ATOM   1030 H  HG   . LEU A 1 67  ? -14.91838 -4.73394  33.76625 1.000 33.04429 ? 90  LEU A HG   1 
ATOM   1031 H  HD11 . LEU A 1 67  ? -14.47798 -2.88360  34.73913 1.000 48.44388 ? 90  LEU A HD11 1 
ATOM   1032 H  HD12 . LEU A 1 67  ? -15.01601 -3.49230  36.10424 1.000 48.44388 ? 90  LEU A HD12 1 
ATOM   1033 H  HD13 . LEU A 1 67  ? -13.47627 -3.61353  35.73275 1.000 48.44388 ? 90  LEU A HD13 1 
ATOM   1034 H  HD21 . LEU A 1 67  ? -12.65728 -5.27831  34.23889 1.000 35.14220 ? 90  LEU A HD21 1 
ATOM   1035 H  HD22 . LEU A 1 67  ? -13.14434 -6.08215  35.51956 1.000 35.14220 ? 90  LEU A HD22 1 
ATOM   1036 H  HD23 . LEU A 1 67  ? -13.54758 -6.58264  34.06683 1.000 35.14220 ? 90  LEU A HD23 1 
ATOM   1037 N  N    . LEU A 1 68  ? -18.14254 -5.84723  33.24083 1.000 24.26062 ? 91  LEU A N    1 
ATOM   1038 C  CA   . LEU A 1 68  ? -18.45860 -5.74789  31.81732 1.000 23.08038 ? 91  LEU A CA   1 
ATOM   1039 C  C    . LEU A 1 68  ? -19.61367 -4.77492  31.56051 1.000 21.10892 ? 91  LEU A C    1 
ATOM   1040 O  O    . LEU A 1 68  ? -19.74229 -4.25750  30.44527 1.000 25.17720 ? 91  LEU A O    1 
ATOM   1041 C  CB   . LEU A 1 68  ? -18.77499 -7.13914  31.25461 1.000 22.94124 ? 91  LEU A CB   1 
ATOM   1042 C  CG   . LEU A 1 68  ? -17.59393 -8.12442  31.24418 1.000 26.36078 ? 91  LEU A CG   1 
ATOM   1043 C  CD1  . LEU A 1 68  ? -17.98236 -9.48560  30.63735 1.000 31.40873 ? 91  LEU A CD1  1 
ATOM   1044 C  CD2  . LEU A 1 68  ? -16.41099 -7.56604  30.50306 1.000 24.95104 ? 91  LEU A CD2  1 
ATOM   1045 H  H    . LEU A 1 68  ? -18.31447 -6.60702  33.60519 1.000 29.09266 ? 91  LEU A H    1 
ATOM   1046 H  HA   . LEU A 1 68  ? -17.68572 -5.41521  31.33475 1.000 27.67638 ? 91  LEU A HA   1 
ATOM   1047 H  HB2  . LEU A 1 68  ? -19.47839 -7.53404  31.79330 1.000 27.50940 ? 91  LEU A HB2  1 
ATOM   1048 H  HB3  . LEU A 1 68  ? -19.07656 -7.03695  30.33836 1.000 27.50940 ? 91  LEU A HB3  1 
ATOM   1049 H  HG   . LEU A 1 68  ? -17.34041 -8.26604  32.16969 1.000 31.61286 ? 91  LEU A HG   1 
ATOM   1050 H  HD11 . LEU A 1 68  ? -17.20874 -10.07057 30.65281 1.000 37.67040 ? 91  LEU A HD11 1 
ATOM   1051 H  HD12 . LEU A 1 68  ? -18.70007 -9.87240  31.16288 1.000 37.67040 ? 91  LEU A HD12 1 
ATOM   1052 H  HD13 . LEU A 1 68  ? -18.27720 -9.35119  29.72307 1.000 37.67040 ? 91  LEU A HD13 1 
ATOM   1053 H  HD21 . LEU A 1 68  ? -15.76997 -8.27765  30.34944 1.000 29.92116 ? 91  LEU A HD21 1 
ATOM   1054 H  HD22 . LEU A 1 68  ? -16.71199 -7.20328  29.65529 1.000 29.92116 ? 91  LEU A HD22 1 
ATOM   1055 H  HD23 . LEU A 1 68  ? -16.00560 -6.86532  31.03743 1.000 29.92116 ? 91  LEU A HD23 1 
ATOM   1056 N  N    . ASN A 1 69  ? -20.42155 -4.48353  32.56931 1.000 23.28666 ? 92  ASN A N    1 
ATOM   1057 C  CA   . ASN A 1 69  ? -21.49736 -3.51801  32.42071 1.000 24.43827 ? 92  ASN A CA   1 
ATOM   1058 C  C    . ASN A 1 69  ? -21.07152 -2.09500  32.72698 1.000 28.43781 ? 92  ASN A C    1 
ATOM   1059 O  O    . ASN A 1 69  ? -21.86914 -1.17096  32.51786 1.000 26.07638 ? 92  ASN A O    1 
ATOM   1060 C  CB   . ASN A 1 69  ? -22.65155 -3.91272  33.31910 1.000 27.08266 ? 92  ASN A CB   1 
ATOM   1061 C  CG   . ASN A 1 69  ? -23.36899 -5.11726  32.80185 1.000 38.74271 ? 92  ASN A CG   1 
ATOM   1062 O  OD1  . ASN A 1 69  ? -23.55460 -5.26044  31.59451 1.000 41.23498 ? 92  ASN A OD1  1 
ATOM   1063 N  ND2  . ASN A 1 69  ? -23.75277 -6.01028  33.70234 1.000 46.26619 ? 92  ASN A ND2  1 
ATOM   1064 H  H    . ASN A 1 69  ? -20.36634 -4.83346  33.35295 1.000 27.92391 ? 92  ASN A H    1 
ATOM   1065 H  HA   . ASN A 1 69  ? -21.81011 -3.52872  31.50258 1.000 29.30584 ? 92  ASN A HA   1 
ATOM   1066 H  HB2  . ASN A 1 69  ? -22.31233 -4.11754  34.20447 1.000 32.47912 ? 92  ASN A HB2  1 
ATOM   1067 H  HB3  . ASN A 1 69  ? -23.28445 -3.17926  33.36780 1.000 32.47912 ? 92  ASN A HB3  1 
ATOM   1068 H  HD21 . ASN A 1 69  ? -24.16923 -6.72033  33.45339 1.000 55.49935 ? 92  ASN A HD21 1 
ATOM   1069 H  HD22 . ASN A 1 69  ? -23.58540 -5.87984  34.53575 1.000 55.49935 ? 92  ASN A HD22 1 
ATOM   1070 N  N    . GLN A 1 70  ? -19.84448 -1.89919  33.19407 1.000 23.54103 ? 93  GLN A N    1 
ATOM   1071 C  CA   . GLN A 1 70  ? -19.37753 -0.55717  33.51167 1.000 25.33387 ? 93  GLN A CA   1 
ATOM   1072 C  C    . GLN A 1 70  ? -19.36503 0.30967   32.26391 1.000 25.05843 ? 93  GLN A C    1 
ATOM   1073 O  O    . GLN A 1 70  ? -18.87246 -0.09751  31.19930 1.000 21.31675 ? 93  GLN A O    1 
ATOM   1074 C  CB   . GLN A 1 70  ? -17.97885 -0.60265  34.12998 1.000 32.82902 ? 93  GLN A CB   1 
ATOM   1075 C  CG   . GLN A 1 70  ? -17.38544 0.76958   34.46242 1.000 48.95463 ? 93  GLN A CG   1 
ATOM   1076 C  CD   . GLN A 1 70  ? -15.95587 0.69115   35.01060 1.000 45.89236 ? 93  GLN A CD   1 
ATOM   1077 O  OE1  . GLN A 1 70  ? -15.58953 -0.25428  35.72157 1.000 47.06769 ? 93  GLN A OE1  1 
ATOM   1078 N  NE2  . GLN A 1 70  ? -15.15084 1.69741   34.68960 1.000 52.03257 ? 93  GLN A NE2  1 
ATOM   1079 H  H    . GLN A 1 70  ? -19.26742 -2.52108  33.33496 1.000 28.22915 ? 93  GLN A H    1 
ATOM   1080 H  HA   . GLN A 1 70  ? -19.97862 -0.15893  34.16052 1.000 30.38056 ? 93  GLN A HA   1 
ATOM   1081 H  HB2  . GLN A 1 70  ? -18.02246 -1.11053  34.95525 1.000 39.37474 ? 93  GLN A HB2  1 
ATOM   1082 H  HB3  . GLN A 1 70  ? -17.37862 -1.03742  33.50420 1.000 39.37474 ? 93  GLN A HB3  1 
ATOM   1083 H  HG2  . GLN A 1 70  ? -17.36647 1.30793   33.65575 1.000 58.72547 ? 93  GLN A HG2  1 
ATOM   1084 H  HG3  . GLN A 1 70  ? -17.93934 1.19756   35.13394 1.000 58.72547 ? 93  GLN A HG3  1 
ATOM   1085 H  HE21 . GLN A 1 70  ? -15.44234 2.34222   34.20088 1.000 62.41900 ? 93  GLN A HE21 1 
ATOM   1086 H  HE22 . GLN A 1 70  ? -14.33802 1.70423   34.97046 1.000 62.41900 ? 93  GLN A HE22 1 
ATOM   1087 N  N    . ARG A 1 71  ? -19.87020 1.53185   32.41151 1.000 29.65886 ? 94  ARG A N    1 
ATOM   1088 C  CA   . ARG A 1 71  ? -19.98289 2.45853   31.29539 1.000 29.38925 ? 94  ARG A CA   1 
ATOM   1089 C  C    . ARG A 1 71  ? -18.71005 3.29347   31.13870 1.000 32.81849 ? 94  ARG A C    1 
ATOM   1090 O  O    . ARG A 1 71  ? -18.13985 3.77367   32.12740 1.000 28.38002 ? 94  ARG A O    1 
ATOM   1091 C  CB   . ARG A 1 71  ? -21.16700 3.40741   31.49460 1.000 33.52481 ? 94  ARG A CB   1 
ATOM   1092 C  CG   . ARG A 1 71  ? -22.50505 2.76789   31.91900 1.000 32.97077 ? 94  ARG A CG   1 
ATOM   1093 C  CD   . ARG A 1 71  ? -23.00723 1.78607   30.86571 1.000 31.73049 ? 94  ARG A CD   1 
ATOM   1094 N  NE   . ARG A 1 71  ? -23.21388 2.39003   29.55012 1.000 28.53431 ? 94  ARG A NE   1 
ATOM   1095 C  CZ   . ARG A 1 71  ? -23.80056 1.76582   28.53549 1.000 36.00735 ? 94  ARG A CZ   1 
ATOM   1096 N  NH1  . ARG A 1 71  ? -24.29759 0.54890   28.66805 1.000 27.82776 ? 94  ARG A NH1  1 
ATOM   1097 N  NH2  . ARG A 1 71  ? -23.86698 2.36370   27.35583 1.000 29.91042 ? 94  ARG A NH2  1 
ATOM   1098 H  H    . ARG A 1 71  ? -20.15708 1.84889   33.15769 1.000 35.57056 ? 94  ARG A H    1 
ATOM   1099 H  HA   . ARG A 1 71  ? -20.11714 1.94157   30.48568 1.000 35.24702 ? 94  ARG A HA   1 
ATOM   1100 H  HB2  . ARG A 1 71  ? -20.92706 4.04624   32.18396 1.000 40.20969 ? 94  ARG A HB2  1 
ATOM   1101 H  HB3  . ARG A 1 71  ? -21.32663 3.86836   30.65618 1.000 40.20969 ? 94  ARG A HB3  1 
ATOM   1102 H  HG2  . ARG A 1 71  ? -22.38218 2.28643   32.75207 1.000 39.54485 ? 94  ARG A HG2  1 
ATOM   1103 H  HG3  . ARG A 1 71  ? -23.17250 3.46251   32.03260 1.000 39.54485 ? 94  ARG A HG3  1 
ATOM   1104 H  HD2  . ARG A 1 71  ? -22.35547 1.07469   30.76543 1.000 38.05651 ? 94  ARG A HD2  1 
ATOM   1105 H  HD3  . ARG A 1 71  ? -23.85591 1.41948   31.15940 1.000 38.05651 ? 94  ARG A HD3  1 
ATOM   1106 H  HE   . ARG A 1 71  ? -22.93973 3.19572   29.42642 1.000 34.22110 ? 94  ARG A HE   1 
ATOM   1107 H  HH11 . ARG A 1 71  ? -24.24514 0.14303   29.42443 1.000 33.37323 ? 94  ARG A HH11 1 
ATOM   1108 H  HH12 . ARG A 1 71  ? -24.67358 0.16263   27.99795 1.000 33.37323 ? 94  ARG A HH12 1 
ATOM   1109 H  HH21 . ARG A 1 71  ? -23.53195 3.14896   27.25227 1.000 35.87242 ? 94  ARG A HH21 1 
ATOM   1110 H  HH22 . ARG A 1 71  ? -24.24514 1.96674   26.69325 1.000 35.87242 ? 94  ARG A HH22 1 
ATOM   1111 N  N    . VAL A 1 72  ? -18.33291 3.52782   29.87842 1.000 22.95106 ? 95  VAL A N    1 
ATOM   1112 C  CA   . VAL A 1 72  ? -17.14053 4.26659   29.47437 1.000 24.81152 ? 95  VAL A CA   1 
ATOM   1113 C  C    . VAL A 1 72  ? -17.55796 5.38241   28.51712 1.000 20.39450 ? 95  VAL A C    1 
ATOM   1114 O  O    . VAL A 1 72  ? -18.14317 5.10753   27.46470 1.000 22.84275 ? 95  VAL A O    1 
ATOM   1115 C  CB   . VAL A 1 72  ? -16.13045 3.32861   28.78322 1.000 26.66577 ? 95  VAL A CB   1 
ATOM   1116 C  CG1  . VAL A 1 72  ? -14.90282 4.08531   28.31387 1.000 30.18490 ? 95  VAL A CG1  1 
ATOM   1117 C  CG2  . VAL A 1 72  ? -15.75375 2.17064   29.70102 1.000 26.72606 ? 95  VAL A CG2  1 
ATOM   1118 H  H    . VAL A 1 72  ? -18.78224 3.24992   29.19984 1.000 27.52119 ? 95  VAL A H    1 
ATOM   1119 H  HA   . VAL A 1 72  ? -16.73209 4.67885   30.25162 1.000 29.75374 ? 95  VAL A HA   1 
ATOM   1120 H  HB   . VAL A 1 72  ? -16.55199 2.95486   27.99359 1.000 31.97885 ? 95  VAL A HB   1 
ATOM   1121 H  HG11 . VAL A 1 72  ? -14.20417 3.44901   28.09498 1.000 36.20180 ? 95  VAL A HG11 1 
ATOM   1122 H  HG12 . VAL A 1 72  ? -15.13381 4.60601   27.52875 1.000 36.20180 ? 95  VAL A HG12 1 
ATOM   1123 H  HG13 . VAL A 1 72  ? -14.60356 4.67362   29.02467 1.000 36.20180 ? 95  VAL A HG13 1 
ATOM   1124 H  HG21 . VAL A 1 72  ? -15.05185 1.64975   29.28041 1.000 32.05119 ? 95  VAL A HG21 1 
ATOM   1125 H  HG22 . VAL A 1 72  ? -15.43954 2.52721   30.54661 1.000 32.05119 ? 95  VAL A HG22 1 
ATOM   1126 H  HG23 . VAL A 1 72  ? -16.53581 1.61550   29.84627 1.000 32.05119 ? 95  VAL A HG23 1 
ATOM   1127 N  N    . GLU A 1 73  ? -17.21337 6.62109   28.84482 1.000 22.09311 ? 96  GLU A N    1 
ATOM   1128 C  CA   . GLU A 1 73  ? -17.56913 7.74939   27.99668 1.000 24.52048 ? 96  GLU A CA   1 
ATOM   1129 C  C    . GLU A 1 73  ? -16.76644 7.70546   26.70534 1.000 21.78325 ? 96  GLU A C    1 
ATOM   1130 O  O    . GLU A 1 73  ? -15.57663 7.39700   26.71627 1.000 22.93341 ? 96  GLU A O    1 
ATOM   1131 C  CB   . GLU A 1 73  ? -17.28178 9.09039   28.69301 1.000 27.28970 ? 96  GLU A CB   1 
ATOM   1132 C  CG   . GLU A 1 73  ? -17.99057 9.31677   30.02155 1.000 41.31953 ? 96  GLU A CG   1 
ATOM   1133 C  CD   . GLU A 1 73  ? -19.29930 10.07044  29.87856 1.000 59.76682 ? 96  GLU A CD   1 
ATOM   1134 O  OE1  . GLU A 1 73  ? -19.61421 10.51007  28.74533 1.000 67.27475 ? 96  GLU A OE1  1 
ATOM   1135 O  OE2  . GLU A 1 73  ? -20.01130 10.22201  30.90312 1.000 56.98998 ? 96  GLU A OE2  1 
ATOM   1136 H  H    . GLU A 1 73  ? -16.77373 6.83514   29.55228 1.000 26.49165 ? 96  GLU A H    1 
ATOM   1137 H  HA   . GLU A 1 73  ? -18.51868 7.69769   27.80540 1.000 29.40450 ? 96  GLU A HA   1 
ATOM   1138 H  HB2  . GLU A 1 73  ? -16.32848 9.14533   28.86363 1.000 32.72756 ? 96  GLU A HB2  1 
ATOM   1139 H  HB3  . GLU A 1 73  ? -17.55396 9.80587   28.09727 1.000 32.72756 ? 96  GLU A HB3  1 
ATOM   1140 H  HG2  . GLU A 1 73  ? -18.18447 8.45635   30.42526 1.000 49.56335 ? 96  GLU A HG2  1 
ATOM   1141 H  HG3  . GLU A 1 73  ? -17.41105 9.83313   30.60329 1.000 49.56335 ? 96  GLU A HG3  1 
ATOM   1142 N  N    . ILE A 1 74  ? -17.41120 8.06160   25.60085 1.000 20.61853 ? 97  ILE A N    1 
ATOM   1143 C  CA   . ILE A 1 74  ? -16.75439 8.21283   24.30946 1.000 26.96239 ? 97  ILE A CA   1 
ATOM   1144 C  C    . ILE A 1 74  ? -16.80575 9.69651   23.95051 1.000 22.54756 ? 97  ILE A C    1 
ATOM   1145 O  O    . ILE A 1 74  ? -17.89201 10.25394  23.76170 1.000 27.32817 ? 97  ILE A O    1 
ATOM   1146 C  CB   . ILE A 1 74  ? -17.43207 7.34847   23.23088 1.000 20.27949 ? 97  ILE A CB   1 
ATOM   1147 C  CG1  . ILE A 1 74  ? -17.56465 5.88469   23.67032 1.000 27.24541 ? 97  ILE A CG1  1 
ATOM   1148 C  CG2  . ILE A 1 74  ? -16.65649 7.46534   21.90854 1.000 22.63456 ? 97  ILE A CG2  1 
ATOM   1149 C  CD1  . ILE A 1 74  ? -16.24375 5.14333   23.94796 1.000 27.15690 ? 97  ILE A CD1  1 
ATOM   1150 H  H    . ILE A 1 74  ? -18.25496 8.22582   25.57448 1.000 24.72216 ? 97  ILE A H    1 
ATOM   1151 H  HA   . ILE A 1 74  ? -15.82535 7.94104   24.37205 1.000 32.33478 ? 97  ILE A HA   1 
ATOM   1152 H  HB   . ILE A 1 74  ? -18.33332 7.68252   23.10029 1.000 24.31531 ? 97  ILE A HB   1 
ATOM   1153 H  HG12 . ILE A 1 74  ? -18.08523 5.85933   24.48840 1.000 32.67441 ? 97  ILE A HG12 1 
ATOM   1154 H  HG13 . ILE A 1 74  ? -18.02493 5.39773   22.96896 1.000 32.67441 ? 97  ILE A HG13 1 
ATOM   1155 H  HG21 . ILE A 1 74  ? -17.00164 6.81106   21.28110 1.000 27.14140 ? 97  ILE A HG21 1 
ATOM   1156 H  HG22 . ILE A 1 74  ? -16.77359 8.35969   21.55172 1.000 27.14140 ? 97  ILE A HG22 1 
ATOM   1157 H  HG23 . ILE A 1 74  ? -15.71630 7.29728   22.07796 1.000 27.14140 ? 97  ILE A HG23 1 
ATOM   1158 H  HD11 . ILE A 1 74  ? -16.44035 4.21905   24.16693 1.000 32.56819 ? 97  ILE A HD11 1 
ATOM   1159 H  HD12 . ILE A 1 74  ? -15.68610 5.18407   23.15533 1.000 32.56819 ? 97  ILE A HD12 1 
ATOM   1160 H  HD13 . ILE A 1 74  ? -15.79215 5.57078   24.69244 1.000 32.56819 ? 97  ILE A HD13 1 
ATOM   1161 N  N    . LYS A 1 75  ? -15.64230 10.33690  23.85322 1.000 27.82768 ? 98  LYS A N    1 
ATOM   1162 C  CA   . LYS A 1 75  ? -15.54181 11.75858  23.54719 1.000 34.52945 ? 98  LYS A CA   1 
ATOM   1163 C  C    . LYS A 1 75  ? -14.93632 11.94824  22.16081 1.000 28.45348 ? 98  LYS A C    1 
ATOM   1164 O  O    . LYS A 1 75  ? -14.26317 11.06413  21.62865 1.000 24.99439 ? 98  LYS A O    1 
ATOM   1165 C  CB   . LYS A 1 75  ? -14.69707 12.50135  24.60095 1.000 28.68378 ? 98  LYS A CB   1 
ATOM   1166 C  CG   . LYS A 1 75  ? -15.25292 12.37749  26.03328 1.000 31.65835 ? 98  LYS A CG   1 
ATOM   1167 C  CD   . LYS A 1 75  ? -14.24993 12.81412  27.10981 1.000 44.39326 ? 98  LYS A CD   1 
ATOM   1168 C  CE   . LYS A 1 75  ? -12.98061 11.94441  27.12533 1.000 50.80764 ? 98  LYS A CE   1 
ATOM   1169 N  NZ   . LYS A 1 75  ? -13.22547 10.49609  27.43830 1.000 48.20504 ? 98  LYS A NZ   1 
ATOM   1170 H  H    . LYS A 1 75  ? -14.87856 9.95728   23.96361 1.000 33.37314 ? 98  LYS A H    1 
ATOM   1171 H  HA   . LYS A 1 75  ? -16.42865 12.15151  23.55146 1.000 41.41525 ? 98  LYS A HA   1 
ATOM   1172 H  HB2  . LYS A 1 75  ? -13.79936 12.13391  24.59774 1.000 34.40046 ? 98  LYS A HB2  1 
ATOM   1173 H  HB3  . LYS A 1 75  ? -14.67062 13.44379  24.37290 1.000 34.40046 ? 98  LYS A HB3  1 
ATOM   1174 H  HG2  . LYS A 1 75  ? -16.04040 12.93792  26.11508 1.000 37.96994 ? 98  LYS A HG2  1 
ATOM   1175 H  HG3  . LYS A 1 75  ? -15.48606 11.45110  26.20163 1.000 37.96994 ? 98  LYS A HG3  1 
ATOM   1176 H  HD2  . LYS A 1 75  ? -13.98304 13.73125  26.94089 1.000 53.25183 ? 98  LYS A HD2  1 
ATOM   1177 H  HD3  . LYS A 1 75  ? -14.67072 12.74616  27.98114 1.000 53.25183 ? 98  LYS A HD3  1 
ATOM   1178 H  HE2  . LYS A 1 75  ? -12.56375 11.98855  26.25059 1.000 60.94909 ? 98  LYS A HE2  1 
ATOM   1179 H  HE3  . LYS A 1 75  ? -12.37525 12.29132  27.79920 1.000 60.94909 ? 98  LYS A HE3  1 
ATOM   1180 H  HZ1  . LYS A 1 75  ? -13.79904 10.15071  26.85192 1.000 57.82596 ? 98  LYS A HZ1  1 
ATOM   1181 H  HZ2  . LYS A 1 75  ? -12.46109 10.04215  27.39638 1.000 57.82596 ? 98  LYS A HZ2  1 
ATOM   1182 H  HZ3  . LYS A 1 75  ? -13.56518 10.41476  28.25688 1.000 57.82596 ? 98  LYS A HZ3  1 
ATOM   1183 N  N    . LYS A 1 76  ? -15.23597 13.09906  21.55487 1.000 26.25969 ? 99  LYS A N    1 
ATOM   1184 C  CA   . LYS A 1 76  ? -14.58858 13.46233  20.30084 1.000 33.23930 ? 99  LYS A CA   1 
ATOM   1185 C  C    . LYS A 1 76  ? -13.07923 13.34043  20.41606 1.000 28.23188 ? 99  LYS A C    1 
ATOM   1186 O  O    . LYS A 1 76  ? -12.39734 12.94280  19.46079 1.000 24.60569 ? 99  LYS A O    1 
ATOM   1187 C  CB   . LYS A 1 76  ? -14.97168 14.88973  19.89650 1.000 28.65801 ? 99  LYS A CB   1 
ATOM   1188 C  CG   . LYS A 1 76  ? -16.06258 14.93811  18.87951 1.000 36.28539 ? 99  LYS A CG   1 
ATOM   1189 C  CD   . LYS A 1 76  ? -16.28372 16.35995  18.39540 1.000 68.00011 ? 99  LYS A CD   1 
ATOM   1190 C  CE   . LYS A 1 76  ? -17.45488 16.44205  17.43250 1.000 68.70233 ? 99  LYS A CE   1 
ATOM   1191 N  NZ   . LYS A 1 76  ? -17.22901 15.56547  16.24936 1.000 76.56003 ? 99  LYS A NZ   1 
ATOM   1192 H  H    . LYS A 1 76  ? -15.80239 13.67666  21.84666 1.000 31.49154 ? 99  LYS A H    1 
ATOM   1193 H  HA   . LYS A 1 76  ? -14.89781 12.86133  19.60508 1.000 39.86708 ? 99  LYS A HA   1 
ATOM   1194 H  HB2  . LYS A 1 76  ? -15.27547 15.36843  20.68355 1.000 34.36953 ? 99  LYS A HB2  1 
ATOM   1195 H  HB3  . LYS A 1 76  ? -14.19308 15.32953  19.52066 1.000 34.36953 ? 99  LYS A HB3  1 
ATOM   1196 H  HG2  . LYS A 1 76  ? -15.82080 14.38763  18.11831 1.000 43.52239 ? 99  LYS A HG2  1 
ATOM   1197 H  HG3  . LYS A 1 76  ? -16.88788 14.61507  19.27375 1.000 43.52239 ? 99  LYS A HG3  1 
ATOM   1198 H  HD2  . LYS A 1 76  ? -16.47256 16.93267  19.15516 1.000 81.58005 ? 99  LYS A HD2  1 
ATOM   1199 H  HD3  . LYS A 1 76  ? -15.48815 16.67050  17.93549 1.000 81.58005 ? 99  LYS A HD3  1 
ATOM   1200 H  HE2  . LYS A 1 76  ? -18.26413 16.15123  17.88132 1.000 82.42271 ? 99  LYS A HE2  1 
ATOM   1201 H  HE3  . LYS A 1 76  ? -17.55686 17.35594  17.12379 1.000 82.42271 ? 99  LYS A HE3  1 
ATOM   1202 H  HZ1  . LYS A 1 76  ? -17.18839 14.71387  16.50478 1.000 91.85196 ? 99  LYS A HZ1  1 
ATOM   1203 H  HZ2  . LYS A 1 76  ? -17.89598 15.66111  15.66789 1.000 91.85196 ? 99  LYS A HZ2  1 
ATOM   1204 H  HZ3  . LYS A 1 76  ? -16.46419 15.78407  15.85014 1.000 91.85196 ? 99  LYS A HZ3  1 
ATOM   1205 N  N    . SER A 1 77  ? -12.53974 13.67458  21.58185 1.000 25.05612 ? 100 SER A N    1 
ATOM   1206 C  CA   . SER A 1 77  ? -11.10114 13.62367  21.77966 1.000 23.24731 ? 100 SER A CA   1 
ATOM   1207 C  C    . SER A 1 77  ? -10.56735 12.19634  21.79470 1.000 25.48038 ? 100 SER A C    1 
ATOM   1208 O  O    . SER A 1 77  ? -9.34447  12.02462  21.74105 1.000 22.68371 ? 100 SER A O    1 
ATOM   1209 C  CB   . SER A 1 77  ? -10.73115 14.33068  23.08701 1.000 26.08181 ? 100 SER A CB   1 
ATOM   1210 O  OG   . SER A 1 77  ? -11.51271 13.79688  24.14842 1.000 31.20381 ? 100 SER A OG   1 
ATOM   1211 H  H    . SER A 1 77  ? -12.98478 13.93309  22.27084 1.000 30.04726 ? 100 SER A H    1 
ATOM   1212 H  HA   . SER A 1 77  ? -10.66597 14.09640  21.05299 1.000 27.87669 ? 100 SER A HA   1 
ATOM   1213 H  HB2  . SER A 1 77  ? -9.79071  14.18645  23.27584 1.000 31.27810 ? 100 SER A HB2  1 
ATOM   1214 H  HB3  . SER A 1 77  ? -10.91052 15.28010  23.00130 1.000 31.27810 ? 100 SER A HB3  1 
ATOM   1215 H  HG   . SER A 1 77  ? -11.30825 12.99276  24.27949 1.000 37.42450 ? 100 SER A HG   1 
ATOM   1216 N  N    . ASP A 1 78  ? -11.44020 11.18786  21.90808 1.000 23.17930 ? 101 ASP A N    1 
ATOM   1217 C  CA   . ASP A 1 78  ? -11.00648 9.78845   21.89287 1.000 23.28429 ? 101 ASP A CA   1 
ATOM   1218 C  C    . ASP A 1 78  ? -10.83034 9.24363   20.48284 1.000 24.78163 ? 101 ASP A C    1 
ATOM   1219 O  O    . ASP A 1 78  ? -10.18119 8.20001   20.31042 1.000 20.05530 ? 101 ASP A O    1 
ATOM   1220 C  CB   . ASP A 1 78  ? -12.01041 8.85976   22.59698 1.000 18.41892 ? 101 ASP A CB   1 
ATOM   1221 C  CG   . ASP A 1 78  ? -12.06444 9.06355   24.09587 1.000 20.59251 ? 101 ASP A CG   1 
ATOM   1222 O  OD1  . ASP A 1 78  ? -11.00672 9.10484   24.73459 1.000 21.79917 ? 101 ASP A OD1  1 
ATOM   1223 O  OD2  . ASP A 1 78  ? -13.17939 9.16879   24.64895 1.000 27.58020 ? 101 ASP A OD2  1 
ATOM   1224 H  H    . ASP A 1 78  ? -12.28982 11.28885  21.99502 1.000 27.79508 ? 101 ASP A H    1 
ATOM   1225 H  HA   . ASP A 1 78  ? -10.16689 9.76193   22.37794 1.000 27.92106 ? 101 ASP A HA   1 
ATOM   1226 H  HB2  . ASP A 1 78  ? -12.89701 9.02843   22.24146 1.000 22.08262 ? 101 ASP A HB2  1 
ATOM   1227 H  HB3  . ASP A 1 78  ? -11.75605 7.93857   22.43077 1.000 22.08262 ? 101 ASP A HB3  1 
ATOM   1228 N  N    . LEU A 1 79  ? -11.44585 9.87761   19.48683 1.000 19.16234 ? 102 LEU A N    1 
ATOM   1229 C  CA   . LEU A 1 79  ? -11.39894 9.34671   18.13256 1.000 20.93532 ? 102 LEU A CA   1 
ATOM   1230 C  C    . LEU A 1 79  ? -9.94513  9.22144   17.67999 1.000 21.51978 ? 102 LEU A C    1 
ATOM   1231 O  O    . LEU A 1 79  ? -9.09440  10.05328  18.00978 1.000 20.62022 ? 102 LEU A O    1 
ATOM   1232 C  CB   . LEU A 1 79  ? -12.20131 10.24379  17.18671 1.000 22.76192 ? 102 LEU A CB   1 
ATOM   1233 C  CG   . LEU A 1 79  ? -13.70744 10.27131  17.48918 1.000 24.48673 ? 102 LEU A CG   1 
ATOM   1234 C  CD1  . LEU A 1 79  ? -14.39566 11.13095  16.46875 1.000 26.77442 ? 102 LEU A CD1  1 
ATOM   1235 C  CD2  . LEU A 1 79  ? -14.30914 8.88400   17.53059 1.000 35.26940 ? 102 LEU A CD2  1 
ATOM   1236 H  H    . LEU A 1 79  ? -11.89168 10.60831  19.57001 1.000 22.97473 ? 102 LEU A H    1 
ATOM   1237 H  HA   . LEU A 1 79  ? -11.80145 8.46475   18.10046 1.000 25.10230 ? 102 LEU A HA   1 
ATOM   1238 H  HB2  . LEU A 1 79  ? -11.86712 11.15141  17.26040 1.000 27.29422 ? 102 LEU A HB2  1 
ATOM   1239 H  HB3  . LEU A 1 79  ? -12.08663 9.92067   16.27933 1.000 27.29422 ? 102 LEU A HB3  1 
ATOM   1240 H  HG   . LEU A 1 79  ? -13.84657 10.64752  18.37236 1.000 29.36399 ? 102 LEU A HG   1 
ATOM   1241 H  HD11 . LEU A 1 79  ? -15.35103 11.11609  16.63595 1.000 32.10922 ? 102 LEU A HD11 1 
ATOM   1242 H  HD12 . LEU A 1 79  ? -14.06097 12.03836  16.54283 1.000 32.10922 ? 102 LEU A HD12 1 
ATOM   1243 H  HD13 . LEU A 1 79  ? -14.20930 10.78088  15.58353 1.000 32.10922 ? 102 LEU A HD13 1 
ATOM   1244 H  HD21 . LEU A 1 79  ? -15.27549 8.95986   17.56702 1.000 42.30320 ? 102 LEU A HD21 1 
ATOM   1245 H  HD22 . LEU A 1 79  ? -14.04512 8.40129   16.73173 1.000 42.30320 ? 102 LEU A HD22 1 
ATOM   1246 H  HD23 . LEU A 1 79  ? -13.98366 8.42202   18.31896 1.000 42.30320 ? 102 LEU A HD23 1 
ATOM   1247 N  N    . VAL A 1 80  ? -9.65254  8.13391   16.97649 1.000 21.87269 ? 103 VAL A N    1 
ATOM   1248 C  CA   . VAL A 1 80  ? -8.34406  7.94352   16.36133 1.000 20.02705 ? 103 VAL A CA   1 
ATOM   1249 C  C    . VAL A 1 80  ? -8.58650  7.71576   14.86810 1.000 27.67599 ? 103 VAL A C    1 
ATOM   1250 O  O    . VAL A 1 80  ? -9.33947  8.47370   14.23938 1.000 29.57885 ? 103 VAL A O    1 
ATOM   1251 C  CB   . VAL A 1 80  ? -7.55934  6.81510   17.05563 1.000 24.07083 ? 103 VAL A CB   1 
ATOM   1252 C  CG1  . VAL A 1 80  ? -7.03722  7.31298   18.39563 1.000 33.31360 ? 103 VAL A CG1  1 
ATOM   1253 C  CG2  . VAL A 1 80  ? -8.39838  5.59077   17.29130 1.000 19.59635 ? 103 VAL A CG2  1 
ATOM   1254 H  H    . VAL A 1 80  ? -10.20007 7.48507   16.83935 1.000 26.22715 ? 103 VAL A H    1 
ATOM   1255 H  HA   . VAL A 1 80  ? -7.78535  8.73121   16.45240 1.000 24.01238 ? 103 VAL A HA   1 
ATOM   1256 H  HB   . VAL A 1 80  ? -6.82810  6.56381   16.46993 1.000 28.86491 ? 103 VAL A HB   1 
ATOM   1257 H  HG11 . VAL A 1 80  ? -6.41723  6.65953   18.75551 1.000 39.95624 ? 103 VAL A HG11 1 
ATOM   1258 H  HG12 . VAL A 1 80  ? -6.58445  8.16051   18.26297 1.000 39.95624 ? 103 VAL A HG12 1 
ATOM   1259 H  HG13 . VAL A 1 80  ? -7.78493  7.42885   19.00258 1.000 39.95624 ? 103 VAL A HG13 1 
ATOM   1260 H  HG21 . VAL A 1 80  ? -7.85400  4.91286   17.72139 1.000 23.49554 ? 103 VAL A HG21 1 
ATOM   1261 H  HG22 . VAL A 1 80  ? -9.14642  5.82570   17.86239 1.000 23.49554 ? 103 VAL A HG22 1 
ATOM   1262 H  HG23 . VAL A 1 80  ? -8.72366  5.26193   16.43868 1.000 23.49554 ? 103 VAL A HG23 1 
ATOM   1263 N  N    . ASN A 1 81  ? -7.97055  6.69268   14.27377 1.000 28.02212 ? 104 ASN A N    1 
ATOM   1264 C  CA   . ASN A 1 81  ? -7.94987  6.56211   12.81642 1.000 24.79939 ? 104 ASN A CA   1 
ATOM   1265 C  C    . ASN A 1 81  ? -8.88649  5.49202   12.27448 1.000 26.31478 ? 104 ASN A C    1 
ATOM   1266 O  O    . ASN A 1 81  ? -8.88095  5.24017   11.06336 1.000 30.95350 ? 104 ASN A O    1 
ATOM   1267 C  CB   . ASN A 1 81  ? -6.51574  6.26277   12.34430 1.000 23.63365 ? 104 ASN A CB   1 
ATOM   1268 C  CG   . ASN A 1 81  ? -5.99472  4.94825   12.88080 1.000 31.53645 ? 104 ASN A CG   1 
ATOM   1269 O  OD1  . ASN A 1 81  ? -6.52616  4.41459   13.84439 1.000 28.76968 ? 104 ASN A OD1  1 
ATOM   1270 N  ND2  . ASN A 1 81  ? -4.93818  4.41701   12.25645 1.000 37.48103 ? 104 ASN A ND2  1 
ATOM   1271 H  H    . ASN A 1 81  ? -7.55915  6.06394   14.69214 1.000 33.60647 ? 104 ASN A H    1 
ATOM   1272 H  HA   . ASN A 1 81  ? -8.23667  7.40830   12.43878 1.000 29.73919 ? 104 ASN A HA   1 
ATOM   1273 H  HB2  . ASN A 1 81  ? -6.50314  6.21909   11.37537 1.000 28.34030 ? 104 ASN A HB2  1 
ATOM   1274 H  HB3  . ASN A 1 81  ? -5.92627  6.96888   12.65226 1.000 28.34030 ? 104 ASN A HB3  1 
ATOM   1275 H  HD21 . ASN A 1 81  ? -4.60887  3.67040   12.52798 1.000 44.95715 ? 104 ASN A HD21 1 
ATOM   1276 H  HD22 . ASN A 1 81  ? -4.58802  4.82198   11.58340 1.000 44.95715 ? 104 ASN A HD22 1 
ATOM   1277 N  N    . TYR A 1 82  ? -9.66196  4.83115   13.12670 1.000 20.47139 ? 105 TYR A N    1 
ATOM   1278 C  CA   . TYR A 1 82  ? -10.52363 3.73233   12.68849 1.000 23.35394 ? 105 TYR A CA   1 
ATOM   1279 C  C    . TYR A 1 82  ? -11.50032 3.44675   13.81928 1.000 20.31081 ? 105 TYR A C    1 
ATOM   1280 O  O    . TYR A 1 82  ? -11.18817 2.68871   14.76017 1.000 18.45146 ? 105 TYR A O    1 
ATOM   1281 C  CB   . TYR A 1 82  ? -9.73930  2.46656   12.33871 1.000 19.14065 ? 105 TYR A CB   1 
ATOM   1282 C  CG   . TYR A 1 82  ? -10.61854 1.48126   11.59107 1.000 19.84578 ? 105 TYR A CG   1 
ATOM   1283 C  CD1  . TYR A 1 82  ? -11.02081 1.75364   10.29454 1.000 24.55969 ? 105 TYR A CD1  1 
ATOM   1284 C  CD2  . TYR A 1 82  ? -11.10012 0.33470   12.19515 1.000 22.43451 ? 105 TYR A CD2  1 
ATOM   1285 C  CE1  . TYR A 1 82  ? -11.82643 0.89882   9.59775  1.000 31.41738 ? 105 TYR A CE1  1 
ATOM   1286 C  CE2  . TYR A 1 82  ? -11.92657 -0.51955  11.51979 1.000 23.70632 ? 105 TYR A CE2  1 
ATOM   1287 C  CZ   . TYR A 1 82  ? -12.28927 -0.24013  10.21634 1.000 24.94061 ? 105 TYR A CZ   1 
ATOM   1288 O  OH   . TYR A 1 82  ? -13.11271 -1.09028  9.51102  1.000 26.04829 ? 105 TYR A OH   1 
ATOM   1289 H  H    . TYR A 1 82  ? -9.70958  4.99842   13.96893 1.000 24.54559 ? 105 TYR A H    1 
ATOM   1290 H  HA   . TYR A 1 82  ? -10.98602 3.98366   11.87368 1.000 28.00465 ? 105 TYR A HA   1 
ATOM   1291 H  HB2  . TYR A 1 82  ? -8.98548  2.69847   11.77403 1.000 22.94870 ? 105 TYR A HB2  1 
ATOM   1292 H  HB3  . TYR A 1 82  ? -9.42575  2.04439   13.15380 1.000 22.94870 ? 105 TYR A HB3  1 
ATOM   1293 H  HD1  . TYR A 1 82  ? -10.73490 2.53940   9.88742  1.000 29.45154 ? 105 TYR A HD1  1 
ATOM   1294 H  HD2  . TYR A 1 82  ? -10.85871 0.14207   13.07237 1.000 26.90133 ? 105 TYR A HD2  1 
ATOM   1295 H  HE1  . TYR A 1 82  ? -12.05925 1.08399   8.71661  1.000 37.68077 ? 105 TYR A HE1  1 
ATOM   1296 H  HE2  . TYR A 1 82  ? -12.24413 -1.28758  11.93713 1.000 28.42750 ? 105 TYR A HE2  1 
ATOM   1297 H  HH   . TYR A 1 82  ? -13.31636 -1.75258  9.98587  1.000 31.23787 ? 105 TYR A HH   1 
ATOM   1298 N  N    . ASN A 1 83  ? -12.68803 4.05227   13.72421 1.000 20.24854 ? 106 ASN A N    1 
ATOM   1299 C  CA   . ASN A 1 83  ? -13.61909 4.14110   14.84791 1.000 20.57062 ? 106 ASN A CA   1 
ATOM   1300 C  C    . ASN A 1 83  ? -15.02693 3.77917   14.39700 1.000 19.28422 ? 106 ASN A C    1 
ATOM   1301 O  O    . ASN A 1 83  ? -15.97680 4.51902   14.66057 1.000 23.91845 ? 106 ASN A O    1 
ATOM   1302 C  CB   . ASN A 1 83  ? -13.63642 5.55631   15.42081 1.000 31.43762 ? 106 ASN A CB   1 
ATOM   1303 C  CG   . ASN A 1 83  ? -12.33571 6.29255   15.22335 1.000 27.08036 ? 106 ASN A CG   1 
ATOM   1304 O  OD1  . ASN A 1 83  ? -11.30826 5.88209   15.74445 1.000 22.69802 ? 106 ASN A OD1  1 
ATOM   1305 N  ND2  . ASN A 1 83  ? -12.36837 7.37955   14.47166 1.000 30.97124 ? 106 ASN A ND2  1 
ATOM   1306 H  H    . ASN A 1 83  ? -12.98016 4.42485   13.00626 1.000 24.27817 ? 106 ASN A H    1 
ATOM   1307 H  HA   . ASN A 1 83  ? -13.32709 3.52056   15.53389 1.000 24.66466 ? 106 ASN A HA   1 
ATOM   1308 H  HB2  . ASN A 1 83  ? -14.33632 6.06467   14.98193 1.000 37.70506 ? 106 ASN A HB2  1 
ATOM   1309 H  HB3  . ASN A 1 83  ? -13.80969 5.50761   16.37397 1.000 37.70506 ? 106 ASN A HB3  1 
ATOM   1310 H  HD21 . ASN A 1 83  ? -11.64813 7.82884   14.33383 1.000 37.14541 ? 106 ASN A HD21 1 
ATOM   1311 H  HD22 . ASN A 1 83  ? -13.10985 7.63739   14.12049 1.000 37.14541 ? 106 ASN A HD22 1 
ATOM   1312 N  N    . PRO A 1 84  ? -15.19144 2.67102   13.65853 1.000 20.90538 ? 107 PRO A N    1 
ATOM   1313 C  CA   . PRO A 1 84  ? -16.49477 2.40041   13.02563 1.000 23.12547 ? 107 PRO A CA   1 
ATOM   1314 C  C    . PRO A 1 84  ? -17.66511 2.32265   13.99630 1.000 21.55424 ? 107 PRO A C    1 
ATOM   1315 O  O    . PRO A 1 84  ? -18.79191 2.67730   13.62774 1.000 27.54670 ? 107 PRO A O    1 
ATOM   1316 C  CB   . PRO A 1 84  ? -16.26454 1.05115   12.31556 1.000 29.30968 ? 107 PRO A CB   1 
ATOM   1317 C  CG   . PRO A 1 84  ? -15.09105 0.43938   13.03730 1.000 27.40777 ? 107 PRO A CG   1 
ATOM   1318 C  CD   . PRO A 1 84  ? -14.21105 1.61257   13.35443 1.000 21.47524 ? 107 PRO A CD   1 
ATOM   1319 H  HA   . PRO A 1 84  ? -16.67904 3.09216   12.37109 1.000 27.73048 ? 107 PRO A HA   1 
ATOM   1320 H  HB2  . PRO A 1 84  ? -17.05400 0.49360   12.39797 1.000 35.15154 ? 107 PRO A HB2  1 
ATOM   1321 H  HB3  . PRO A 1 84  ? -16.05941 1.19947   11.37917 1.000 35.15154 ? 107 PRO A HB3  1 
ATOM   1322 H  HG2  . PRO A 1 84  ? -15.38966 -0.00388  13.84678 1.000 32.86924 ? 107 PRO A HG2  1 
ATOM   1323 H  HG3  . PRO A 1 84  ? -14.63631 -0.19423  12.46054 1.000 32.86924 ? 107 PRO A HG3  1 
ATOM   1324 H  HD2  . PRO A 1 84  ? -13.64765 1.42825   14.12222 1.000 25.75021 ? 107 PRO A HD2  1 
ATOM   1325 H  HD3  . PRO A 1 84  ? -13.66317 1.85376   12.59117 1.000 25.75021 ? 107 PRO A HD3  1 
ATOM   1326 N  N    . ILE A 1 85  ? -17.43868 1.84038   15.20963 1.000 20.17125 ? 108 ILE A N    1 
ATOM   1327 C  CA   . ILE A 1 85  ? -18.47984 1.72200   16.21968 1.000 23.57296 ? 108 ILE A CA   1 
ATOM   1328 C  C    . ILE A 1 85  ? -18.47373 2.93736   17.13443 1.000 23.32804 ? 108 ILE A C    1 
ATOM   1329 O  O    . ILE A 1 85  ? -19.51400 3.51931   17.42305 1.000 22.83500 ? 108 ILE A O    1 
ATOM   1330 C  CB   . ILE A 1 85  ? -18.30374 0.42044   17.04334 1.000 20.50842 ? 108 ILE A CB   1 
ATOM   1331 C  CG1  . ILE A 1 85  ? -18.36363 -0.85130  16.17061 1.000 21.78957 ? 108 ILE A CG1  1 
ATOM   1332 C  CG2  . ILE A 1 85  ? -19.37675 0.34229   18.12700 1.000 22.11002 ? 108 ILE A CG2  1 
ATOM   1333 C  CD1  . ILE A 1 85  ? -19.56579 -0.92982  15.29345 1.000 24.91501 ? 108 ILE A CD1  1 
ATOM   1334 H  H    . ILE A 1 85  ? -16.66893 1.56760   15.47923 1.000 24.18542 ? 108 ILE A H    1 
ATOM   1335 H  HA   . ILE A 1 85  ? -19.33768 1.66995   15.76991 1.000 28.26747 ? 108 ILE A HA   1 
ATOM   1336 H  HB   . ILE A 1 85  ? -17.41983 0.45931   17.44094 1.000 24.59002 ? 108 ILE A HB   1 
ATOM   1337 H  HG12 . ILE A 1 85  ? -17.57996 -0.87339  15.59941 1.000 26.12740 ? 108 ILE A HG12 1 
ATOM   1338 H  HG13 . ILE A 1 85  ? -18.37205 -1.62737  16.75246 1.000 26.12740 ? 108 ILE A HG13 1 
ATOM   1339 H  HG21 . ILE A 1 85  ? -19.40923 -0.56271  18.47458 1.000 26.51194 ? 108 ILE A HG21 1 
ATOM   1340 H  HG22 . ILE A 1 85  ? -19.15258 0.96211   18.83867 1.000 26.51194 ? 108 ILE A HG22 1 
ATOM   1341 H  HG23 . ILE A 1 85  ? -20.23417 0.57900   17.74008 1.000 26.51194 ? 108 ILE A HG23 1 
ATOM   1342 H  HD11 . ILE A 1 85  ? -19.62653 -1.82304  14.92013 1.000 29.87793 ? 108 ILE A HD11 1 
ATOM   1343 H  HD12 . ILE A 1 85  ? -20.35584 -0.73801  15.82253 1.000 29.87793 ? 108 ILE A HD12 1 
ATOM   1344 H  HD13 . ILE A 1 85  ? -19.47926 -0.27832  14.58003 1.000 29.87793 ? 108 ILE A HD13 1 
ATOM   1345 N  N    . ALA A 1 86  ? -17.29265 3.32980   17.59671 1.000 22.42619 ? 109 ALA A N    1 
ATOM   1346 C  CA   . ALA A 1 86  ? -17.19968 4.40698   18.57597 1.000 18.83285 ? 109 ALA A CA   1 
ATOM   1347 C  C    . ALA A 1 86  ? -17.66064 5.73124   18.00146 1.000 24.19573 ? 109 ALA A C    1 
ATOM   1348 O  O    . ALA A 1 86  ? -18.28231 6.53307   18.70858 1.000 25.68051 ? 109 ALA A O    1 
ATOM   1349 C  CB   . ALA A 1 86  ? -15.76860 4.52247   19.09412 1.000 21.03347 ? 109 ALA A CB   1 
ATOM   1350 H  H    . ALA A 1 86  ? -16.53644 2.99340   17.36310 1.000 26.89135 ? 109 ALA A H    1 
ATOM   1351 H  HA   . ALA A 1 86  ? -17.77901 4.19028   19.32317 1.000 22.57934 ? 109 ALA A HA   1 
ATOM   1352 H  HB1  . ALA A 1 86  ? -15.72564 5.23955   19.74592 1.000 25.22008 ? 109 ALA A HB1  1 
ATOM   1353 H  HB2  . ALA A 1 86  ? -15.51406 3.68316   19.50845 1.000 25.22008 ? 109 ALA A HB2  1 
ATOM   1354 H  HB3  . ALA A 1 86  ? -15.17785 4.71637   18.34960 1.000 25.22008 ? 109 ALA A HB3  1 
ATOM   1355 N  N    . GLU A 1 87  ? -17.37557 5.98540   16.71689 1.000 25.83439 ? 110 GLU A N    1 
ATOM   1356 C  CA   . GLU A 1 87  ? -17.81625 7.24496   16.12523 1.000 34.17500 ? 110 GLU A CA   1 
ATOM   1357 C  C    . GLU A 1 87  ? -19.32824 7.39394   16.19996 1.000 33.49298 ? 110 GLU A C    1 
ATOM   1358 O  O    . GLU A 1 87  ? -19.82644 8.51615   16.12896 1.000 30.20096 ? 110 GLU A O    1 
ATOM   1359 C  CB   . GLU A 1 87  ? -17.33997 7.36722   14.67195 1.000 26.76691 ? 110 GLU A CB   1 
ATOM   1360 C  CG   . GLU A 1 87  ? -18.09205 6.51177   13.67808 1.000 36.43783 ? 110 GLU A CG   1 
ATOM   1361 C  CD   . GLU A 1 87  ? -17.51746 6.60797   12.27031 1.000 38.03694 ? 110 GLU A CD   1 
ATOM   1362 O  OE1  . GLU A 1 87  ? -16.43168 7.18375   12.10097 1.000 42.01898 ? 110 GLU A OE1  1 
ATOM   1363 O  OE2  . GLU A 1 87  ? -18.15950 6.09568   11.33940 1.000 50.48294 ? 110 GLU A OE2  1 
ATOM   1364 H  H    . GLU A 1 87  ? -16.94379 5.46127   16.18921 1.000 30.98119 ? 110 GLU A H    1 
ATOM   1365 H  HA   . GLU A 1 87  ? -17.40968 7.97729   16.61440 1.000 40.98992 ? 110 GLU A HA   1 
ATOM   1366 H  HB2  . GLU A 1 87  ? -17.43862 8.29113   14.39345 1.000 32.10021 ? 110 GLU A HB2  1 
ATOM   1367 H  HB3  . GLU A 1 87  ? -16.40651 7.10655   14.63204 1.000 32.10021 ? 110 GLU A HB3  1 
ATOM   1368 H  HG2  . GLU A 1 87  ? -18.04543 5.58455   13.95913 1.000 43.70531 ? 110 GLU A HG2  1 
ATOM   1369 H  HG3  . GLU A 1 87  ? -19.01687 6.80257   13.64585 1.000 43.70531 ? 110 GLU A HG3  1 
ATOM   1370 N  N    . LYS A 1 88  ? -20.06416 6.30053   16.38730 1.000 30.86134 ? 111 LYS A N    1 
ATOM   1371 C  CA   . LYS A 1 88  ? -21.52003 6.35638   16.51077 1.000 36.00425 ? 111 LYS A CA   1 
ATOM   1372 C  C    . LYS A 1 88  ? -21.99998 6.62956   17.93952 1.000 32.56286 ? 111 LYS A C    1 
ATOM   1373 O  O    . LYS A 1 88  ? -23.19941 6.84228   18.14797 1.000 32.57744 ? 111 LYS A O    1 
ATOM   1374 C  CB   . LYS A 1 88  ? -22.14268 5.03689   16.04273 1.000 35.42853 ? 111 LYS A CB   1 
ATOM   1375 C  CG   . LYS A 1 88  ? -21.79770 4.58736   14.62906 1.000 44.90446 ? 111 LYS A CG   1 
ATOM   1376 C  CD   . LYS A 1 88  ? -22.44372 3.21685   14.36806 1.000 54.32675 ? 111 LYS A CD   1 
ATOM   1377 C  CE   . LYS A 1 88  ? -21.85440 2.47877   13.16976 1.000 62.95232 ? 111 LYS A CE   1 
ATOM   1378 N  NZ   . LYS A 1 88  ? -22.40199 1.08265   13.07383 1.000 68.03033 ? 111 LYS A NZ   1 
ATOM   1379 H  H    . LYS A 1 88  ? -19.74083 5.50587   16.44702 1.000 37.01353 ? 111 LYS A H    1 
ATOM   1380 H  HA   . LYS A 1 88  ? -21.83914 7.07240   15.93947 1.000 43.18502 ? 111 LYS A HA   1 
ATOM   1381 H  HB2  . LYS A 1 88  ? -21.84862 4.33497   16.64419 1.000 42.49416 ? 111 LYS A HB2  1 
ATOM   1382 H  HB3  . LYS A 1 88  ? -23.10752 5.12738   16.08501 1.000 42.49416 ? 111 LYS A HB3  1 
ATOM   1383 H  HG2  . LYS A 1 88  ? -22.14230 5.22608   13.98549 1.000 53.86528 ? 111 LYS A HG2  1 
ATOM   1384 H  HG3  . LYS A 1 88  ? -20.83588 4.50595   14.53329 1.000 53.86528 ? 111 LYS A HG3  1 
ATOM   1385 H  HD2  . LYS A 1 88  ? -22.31787 2.65761   15.15056 1.000 65.17202 ? 111 LYS A HD2  1 
ATOM   1386 H  HD3  . LYS A 1 88  ? -23.39054 3.34423   14.20012 1.000 65.17202 ? 111 LYS A HD3  1 
ATOM   1387 H  HE2  . LYS A 1 88  ? -22.08037 2.95387   12.35483 1.000 75.52271 ? 111 LYS A HE2  1 
ATOM   1388 H  HE3  . LYS A 1 88  ? -20.89069 2.42465   13.26587 1.000 75.52271 ? 111 LYS A HE3  1 
ATOM   1389 H  HZ1  . LYS A 1 88  ? -22.01590 0.64997   12.39868 1.000 81.61632 ? 111 LYS A HZ1  1 
ATOM   1390 H  HZ2  . LYS A 1 88  ? -22.24213 0.64039   13.82944 1.000 81.61632 ? 111 LYS A HZ2  1 
ATOM   1391 H  HZ3  . LYS A 1 88  ? -23.28070 1.10920   12.93507 1.000 81.61632 ? 111 LYS A HZ3  1 
ATOM   1392 N  N    . HIS A 1 89  ? -21.10867 6.60363   18.92786 1.000 32.22460 ? 112 HIS A N    1 
ATOM   1393 C  CA   . HIS A 1 89  ? -21.49088 6.78213   20.32406 1.000 37.73366 ? 112 HIS A CA   1 
ATOM   1394 C  C    . HIS A 1 89  ? -20.78080 7.97361   20.95247 1.000 31.64817 ? 112 HIS A C    1 
ATOM   1395 O  O    . HIS A 1 89  ? -20.69237 8.06576   22.17769 1.000 29.60577 ? 112 HIS A O    1 
ATOM   1396 C  CB   . HIS A 1 89  ? -21.19626 5.51497   21.13208 1.000 26.99923 ? 112 HIS A CB   1 
ATOM   1397 C  CG   . HIS A 1 89  ? -21.96150 4.31888   20.68187 1.000 33.01418 ? 112 HIS A CG   1 
ATOM   1398 N  ND1  . HIS A 1 89  ? -23.15004 3.93721   21.26289 1.000 38.00362 ? 112 HIS A ND1  1 
ATOM   1399 C  CD2  . HIS A 1 89  ? -21.72060 3.42869   19.69086 1.000 28.70218 ? 112 HIS A CD2  1 
ATOM   1400 C  CE1  . HIS A 1 89  ? -23.60887 2.85917   20.65216 1.000 37.80285 ? 112 HIS A CE1  1 
ATOM   1401 N  NE2  . HIS A 1 89  ? -22.76089 2.53091   19.69538 1.000 40.17723 ? 112 HIS A NE2  1 
ATOM   1402 H  H    . HIS A 1 89  ? -20.26517 6.48241   18.81202 1.000 38.64944 ? 112 HIS A H    1 
ATOM   1403 H  HA   . HIS A 1 89  ? -22.44644 6.94470   20.36120 1.000 45.26032 ? 112 HIS A HA   1 
ATOM   1404 H  HB2  . HIS A 1 89  ? -20.25187 5.30815   21.05303 1.000 32.37900 ? 112 HIS A HB2  1 
ATOM   1405 H  HB3  . HIS A 1 89  ? -21.42348 5.67839   22.06083 1.000 32.37900 ? 112 HIS A HB3  1 
ATOM   1406 H  HD2  . HIS A 1 89  ? -20.98959 3.42538   19.11596 1.000 34.42254 ? 112 HIS A HD2  1 
ATOM   1407 H  HE1  . HIS A 1 89  ? -24.39518 2.40852   20.86081 1.000 45.34333 ? 112 HIS A HE1  1 
ATOM   1408 H  HE2  . HIS A 1 89  ? -22.84581 1.86263   19.16079 1.000 48.19260 ? 112 HIS A HE2  1 
ATOM   1409 N  N    . VAL A 1 90  ? -20.26183 8.88434   20.13190 1.000 34.23023 ? 113 VAL A N    1 
ATOM   1410 C  CA   . VAL A 1 90  ? -19.61431 10.07714  20.65590 1.000 31.67326 ? 113 VAL A CA   1 
ATOM   1411 C  C    . VAL A 1 90  ? -20.59337 10.84356  21.52550 1.000 31.29549 ? 113 VAL A C    1 
ATOM   1412 O  O    . VAL A 1 90  ? -21.73485 11.10680  21.12490 1.000 32.21037 ? 113 VAL A O    1 
ATOM   1413 C  CB   . VAL A 1 90  ? -19.08579 10.93731  19.49782 1.000 32.31097 ? 113 VAL A CB   1 
ATOM   1414 C  CG1  . VAL A 1 90  ? -18.63899 12.31163  20.00064 1.000 46.24440 ? 113 VAL A CG1  1 
ATOM   1415 C  CG2  . VAL A 1 90  ? -17.95967 10.21356  18.78829 1.000 33.58636 ? 113 VAL A CG2  1 
ATOM   1416 H  H    . VAL A 1 90  ? -20.27252 8.83363   19.27346 1.000 41.05620 ? 113 VAL A H    1 
ATOM   1417 H  HA   . VAL A 1 90  ? -18.86187 9.81724   21.21015 1.000 37.98783 ? 113 VAL A HA   1 
ATOM   1418 H  HB   . VAL A 1 90  ? -19.79873 11.08552  18.85700 1.000 38.75308 ? 113 VAL A HB   1 
ATOM   1419 H  HG11 . VAL A 1 90  ? -18.08307 12.72982  19.32464 1.000 55.47320 ? 113 VAL A HG11 1 
ATOM   1420 H  HG12 . VAL A 1 90  ? -19.42347 12.85717  20.16763 1.000 55.47320 ? 113 VAL A HG12 1 
ATOM   1421 H  HG13 . VAL A 1 90  ? -18.13379 12.19885  20.82098 1.000 55.47320 ? 113 VAL A HG13 1 
ATOM   1422 H  HG21 . VAL A 1 90  ? -17.62969 10.77254  18.06749 1.000 40.28355 ? 113 VAL A HG21 1 
ATOM   1423 H  HG22 . VAL A 1 90  ? -17.24765 10.03792  19.42318 1.000 40.28355 ? 113 VAL A HG22 1 
ATOM   1424 H  HG23 . VAL A 1 90  ? -18.29747 9.37762   18.43051 1.000 40.28355 ? 113 VAL A HG23 1 
ATOM   1425 N  N    . ASN A 1 91  ? -20.14453 11.22296  22.72340 1.000 30.87050 ? 114 ASN A N    1 
ATOM   1426 C  CA   . ASN A 1 91  ? -20.92740 12.00480  23.70636 1.000 31.14756 ? 114 ASN A CA   1 
ATOM   1427 C  C    . ASN A 1 91  ? -21.91640 11.12021  24.45542 1.000 32.55753 ? 114 ASN A C    1 
ATOM   1428 O  O    . ASN A 1 91  ? -22.73952 11.64088  25.23618 1.000 36.34108 ? 114 ASN A O    1 
ATOM   1429 C  CB   . ASN A 1 91  ? -21.64851 13.18328  23.04959 1.000 37.48658 ? 114 ASN A CB   1 
ATOM   1430 C  CG   . ASN A 1 91  ? -20.67858 14.28484  22.61231 1.000 37.91560 ? 114 ASN A CG   1 
ATOM   1431 O  OD1  . ASN A 1 91  ? -19.60745 14.45224  23.19554 1.000 43.03570 ? 114 ASN A OD1  1 
ATOM   1432 N  ND2  . ASN A 1 91  ? -21.03492 15.00326  21.56919 1.000 46.41198 ? 114 ASN A ND2  1 
ATOM   1433 H  H    . ASN A 1 91  ? -19.35496 11.03333  23.00663 1.000 37.02452 ? 114 ASN A H    1 
ATOM   1434 H  HA   . ASN A 1 91  ? -20.32864 12.37860  24.37169 1.000 37.35700 ? 114 ASN A HA   1 
ATOM   1435 H  HB2  . ASN A 1 91  ? -22.12237 12.86847  22.26394 1.000 44.96381 ? 114 ASN A HB2  1 
ATOM   1436 H  HB3  . ASN A 1 91  ? -22.27489 13.56628  23.68352 1.000 44.96381 ? 114 ASN A HB3  1 
ATOM   1437 H  HD21 . ASN A 1 91  ? -20.52294 15.63357  21.28601 1.000 55.67429 ? 114 ASN A HD21 1 
ATOM   1438 H  HD22 . ASN A 1 91  ? -21.77981 14.84252  21.17056 1.000 55.67429 ? 114 ASN A HD22 1 
ATOM   1439 N  N    . GLY A 1 92  ? -21.85676 9.80340   24.25208 1.000 28.43505 ? 115 GLY A N    1 
ATOM   1440 C  CA   . GLY A 1 92  ? -22.51492 8.84010   25.11575 1.000 38.01512 ? 115 GLY A CA   1 
ATOM   1441 C  C    . GLY A 1 92  ? -21.49521 7.91025   25.75010 1.000 27.11279 ? 115 GLY A C    1 
ATOM   1442 O  O    . GLY A 1 92  ? -20.29022 8.18226   25.71518 1.000 28.13208 ? 115 GLY A O    1 
ATOM   1443 H  H    . GLY A 1 92  ? -21.42853 9.43824   23.60178 1.000 34.10198 ? 115 GLY A H    1 
ATOM   1444 H  HA2  . GLY A 1 92  ? -22.99611 9.30441   25.81844 1.000 45.59806 ? 115 GLY A HA2  1 
ATOM   1445 H  HA3  . GLY A 1 92  ? -23.14298 8.31147   24.59904 1.000 45.59806 ? 115 GLY A HA3  1 
ATOM   1446 N  N    . THR A 1 93  ? -21.96665 6.82507   26.36105 1.000 25.77442 ? 116 THR A N    1 
ATOM   1447 C  CA   . THR A 1 93  ? -21.11331 5.79523   26.92585 1.000 25.00326 ? 116 THR A CA   1 
ATOM   1448 C  C    . THR A 1 93  ? -21.34756 4.48297   26.19509 1.000 24.68158 ? 116 THR A C    1 
ATOM   1449 O  O    . THR A 1 93  ? -22.38541 4.27604   25.56703 1.000 26.81943 ? 116 THR A O    1 
ATOM   1450 C  CB   . THR A 1 93  ? -21.36314 5.59459   28.43117 1.000 27.75974 ? 116 THR A CB   1 
ATOM   1451 O  OG1  . THR A 1 93  ? -22.67974 5.07236   28.64185 1.000 24.91207 ? 116 THR A OG1  1 
ATOM   1452 C  CG2  . THR A 1 93  ? -21.19260 6.91078   29.17243 1.000 26.27884 ? 116 THR A CG2  1 
ATOM   1453 H  H    . THR A 1 93  ? -22.80513 6.66241   26.46150 1.000 30.90922 ? 116 THR A H    1 
ATOM   1454 H  HA   . THR A 1 93  ? -20.18710 6.06023   26.81266 1.000 29.98383 ? 116 THR A HA   1 
ATOM   1455 H  HB   . THR A 1 93  ? -20.72058 4.96245   28.78951 1.000 33.29160 ? 116 THR A HB   1 
ATOM   1456 H  HG1  . THR A 1 93  ? -23.25147 5.59468   28.31643 1.000 29.87440 ? 116 THR A HG1  1 
ATOM   1457 H  HG21 . THR A 1 93  ? -21.30384 6.77139   30.12589 1.000 31.51453 ? 116 THR A HG21 1 
ATOM   1458 H  HG22 . THR A 1 93  ? -20.30735 7.27172   29.00823 1.000 31.51453 ? 116 THR A HG22 1 
ATOM   1459 H  HG23 . THR A 1 93  ? -21.85493 7.55096   28.86848 1.000 31.51453 ? 116 THR A HG23 1 
ATOM   1460 N  N    . MET A 1 94  ? -20.33115 3.61632   26.24042 1.000 21.12083 ? 117 MET A N    1 
ATOM   1461 C  CA   . MET A 1 94  ? -20.44963 2.21132   25.85899 1.000 20.58148 ? 117 MET A CA   1 
ATOM   1462 C  C    . MET A 1 94  ? -19.99617 1.36459   27.04235 1.000 22.45287 ? 117 MET A C    1 
ATOM   1463 O  O    . MET A 1 94  ? -19.13871 1.78146   27.81841 1.000 22.52885 ? 117 MET A O    1 
ATOM   1464 C  CB   . MET A 1 94  ? -19.61063 1.88140   24.62445 1.000 26.47972 ? 117 MET A CB   1 
ATOM   1465 C  CG   . MET A 1 94  ? -20.01281 2.66120   23.35991 1.000 26.42721 ? 117 MET A CG   1 
ATOM   1466 S  SD   . MET A 1 94  ? -18.75743 2.42447   22.08384 1.000 24.77355 ? 117 MET A SD   1 
ATOM   1467 C  CE   . MET A 1 94  ? -18.84577 0.65846   21.80549 1.000 26.81486 ? 117 MET A CE   1 
ATOM   1468 H  H    . MET A 1 94  ? -19.53844 3.82861   26.49760 1.000 25.32491 ? 117 MET A H    1 
ATOM   1469 H  HA   . MET A 1 94  ? -21.36936 2.00406   25.63086 1.000 24.67769 ? 117 MET A HA   1 
ATOM   1470 H  HB2  . MET A 1 94  ? -18.68276 2.08970   24.81567 1.000 31.75558 ? 117 MET A HB2  1 
ATOM   1471 H  HB3  . MET A 1 94  ? -19.70499 0.93593   24.42930 1.000 31.75558 ? 117 MET A HB3  1 
ATOM   1472 H  HG2  . MET A 1 94  ? -20.86338 2.33350   23.02818 1.000 31.69257 ? 117 MET A HG2  1 
ATOM   1473 H  HG3  . MET A 1 94  ? -20.07854 3.60720   23.56401 1.000 31.69257 ? 117 MET A HG3  1 
ATOM   1474 H  HE1  . MET A 1 94  ? -18.20354 0.41416   21.12084 1.000 32.15775 ? 117 MET A HE1  1 
ATOM   1475 H  HE2  . MET A 1 94  ? -18.63819 0.19751   22.63333 1.000 32.15775 ? 117 MET A HE2  1 
ATOM   1476 H  HE3  . MET A 1 94  ? -19.74235 0.42902   21.51497 1.000 32.15775 ? 117 MET A HE3  1 
ATOM   1477 N  N    . SER A 1 95  ? -20.59609 0.19214   27.20069 1.000 21.30841 ? 118 SER A N    1 
ATOM   1478 C  CA   . SER A 1 95  ? -20.12827 -0.72397  28.22999 1.000 25.78615 ? 118 SER A CA   1 
ATOM   1479 C  C    . SER A 1 95  ? -18.79459 -1.35913  27.83083 1.000 21.08823 ? 118 SER A C    1 
ATOM   1480 O  O    . SER A 1 95  ? -18.42227 -1.44115  26.65601 1.000 19.85714 ? 118 SER A O    1 
ATOM   1481 C  CB   . SER A 1 95  ? -21.16833 -1.81252  28.47983 1.000 23.21509 ? 118 SER A CB   1 
ATOM   1482 O  OG   . SER A 1 95  ? -21.18910 -2.69715  27.38094 1.000 22.47952 ? 118 SER A OG   1 
ATOM   1483 H  H    . SER A 1 95  ? -21.26166 -0.09061  26.73523 1.000 25.55001 ? 118 SER A H    1 
ATOM   1484 H  HA   . SER A 1 95  ? -19.99075 -0.23468  29.05618 1.000 30.92330 ? 118 SER A HA   1 
ATOM   1485 H  HB2  . SER A 1 95  ? -20.93476 -2.30275  29.28359 1.000 27.83803 ? 118 SER A HB2  1 
ATOM   1486 H  HB3  . SER A 1 95  ? -22.04271 -1.40520  28.58198 1.000 27.83803 ? 118 SER A HB3  1 
ATOM   1487 H  HG   . SER A 1 95  ? -21.73341 -3.32067  27.52431 1.000 26.95535 ? 118 SER A HG   1 
ATOM   1488 N  N    . LEU A 1 96  ? -18.08206 -1.86678  28.83034 1.000 19.93322 ? 119 LEU A N    1 
ATOM   1489 C  CA   . LEU A 1 96  ? -16.86855 -2.61477  28.52345 1.000 16.62098 ? 119 LEU A CA   1 
ATOM   1490 C  C    . LEU A 1 96  ? -17.14127 -3.87847  27.70003 1.000 16.31748 ? 119 LEU A C    1 
ATOM   1491 O  O    . LEU A 1 96  ? -16.30012 -4.27019  26.88638 1.000 21.07523 ? 119 LEU A O    1 
ATOM   1492 C  CB   . LEU A 1 96  ? -16.13865 -2.96068  29.81643 1.000 21.38833 ? 119 LEU A CB   1 
ATOM   1493 C  CG   . LEU A 1 96  ? -15.28322 -1.80265  30.33952 1.000 25.09317 ? 119 LEU A CG   1 
ATOM   1494 C  CD1  . LEU A 1 96  ? -14.81919 -2.08678  31.75150 1.000 28.05891 ? 119 LEU A CD1  1 
ATOM   1495 C  CD2  . LEU A 1 96  ? -14.06976 -1.53537  29.42385 1.000 22.29891 ? 119 LEU A CD2  1 
ATOM   1496 H  H    . LEU A 1 96  ? -18.27181 -1.79554  29.66611 1.000 23.89979 ? 119 LEU A H    1 
ATOM   1497 H  HA   . LEU A 1 96  ? -16.29083 -2.05111  27.98547 1.000 19.92509 ? 119 LEU A HA   1 
ATOM   1498 H  HB2  . LEU A 1 96  ? -16.79223 -3.18415  30.49745 1.000 25.64592 ? 119 LEU A HB2  1 
ATOM   1499 H  HB3  . LEU A 1 96  ? -15.55455 -3.71827  29.65587 1.000 25.64592 ? 119 LEU A HB3  1 
ATOM   1500 H  HG   . LEU A 1 96  ? -15.82827 -1.00028  30.34477 1.000 30.09173 ? 119 LEU A HG   1 
ATOM   1501 H  HD11 . LEU A 1 96  ? -14.31231 -1.32624  32.07640 1.000 33.65061 ? 119 LEU A HD11 1 
ATOM   1502 H  HD12 . LEU A 1 96  ? -15.59479 -2.23267  32.31547 1.000 33.65061 ? 119 LEU A HD12 1 
ATOM   1503 H  HD13 . LEU A 1 96  ? -14.25995 -2.87932  31.74666 1.000 33.65061 ? 119 LEU A HD13 1 
ATOM   1504 H  HD21 . LEU A 1 96  ? -13.47343 -0.90989  29.86437 1.000 26.73861 ? 119 LEU A HD21 1 
ATOM   1505 H  HD22 . LEU A 1 96  ? -13.60810 -2.37239  29.25900 1.000 26.73861 ? 119 LEU A HD22 1 
ATOM   1506 H  HD23 . LEU A 1 96  ? -14.38293 -1.15978  28.58614 1.000 26.73861 ? 119 LEU A HD23 1 
ATOM   1507 N  N    . ALA A 1 97  ? -18.29619 -4.52448  27.88170 1.000 18.14343 ? 120 ALA A N    1 
ATOM   1508 C  CA   . ALA A 1 97  ? -18.68041 -5.61073  26.98218 1.000 22.33461 ? 120 ALA A CA   1 
ATOM   1509 C  C    . ALA A 1 97  ? -18.79916 -5.11360  25.54617 1.000 19.60704 ? 120 ALA A C    1 
ATOM   1510 O  O    . ALA A 1 97  ? -18.26284 -5.72717  24.61171 1.000 19.32525 ? 120 ALA A O    1 
ATOM   1511 C  CB   . ALA A 1 97  ? -20.01297 -6.21554  27.41219 1.000 21.20906 ? 120 ALA A CB   1 
ATOM   1512 H  H    . ALA A 1 97  ? -18.86315 -4.35591  28.50599 1.000 21.75204 ? 120 ALA A H    1 
ATOM   1513 H  HA   . ALA A 1 97  ? -17.99570 -6.29608  27.03085 1.000 26.78145 ? 120 ALA A HA   1 
ATOM   1514 H  HB1  . ALA A 1 97  ? -20.25040 -6.92654  26.79656 1.000 25.43079 ? 120 ALA A HB1  1 
ATOM   1515 H  HB2  . ALA A 1 97  ? -19.92310 -6.57164  28.30998 1.000 25.43079 ? 120 ALA A HB2  1 
ATOM   1516 H  HB3  . ALA A 1 97  ? -20.69311 -5.52411  27.39715 1.000 25.43079 ? 120 ALA A HB3  1 
ATOM   1517 N  N    . GLU A 1 98  ? -19.51990 -3.99753  25.35226 1.000 18.48214 ? 121 GLU A N    1 
ATOM   1518 C  CA   . GLU A 1 98  ? -19.64671 -3.41936  24.01394 1.000 20.84001 ? 121 GLU A CA   1 
ATOM   1519 C  C    . GLU A 1 98  ? -18.29564 -3.03778  23.43449 1.000 21.27436 ? 121 GLU A C    1 
ATOM   1520 O  O    . GLU A 1 98  ? -18.03808 -3.27393  22.24507 1.000 20.34462 ? 121 GLU A O    1 
ATOM   1521 C  CB   . GLU A 1 98  ? -20.55999 -2.18937  24.04125 1.000 20.48850 ? 121 GLU A CB   1 
ATOM   1522 C  CG   . GLU A 1 98  ? -21.97791 -2.52140  24.39181 1.000 22.82821 ? 121 GLU A CG   1 
ATOM   1523 C  CD   . GLU A 1 98  ? -22.81944 -1.33005  24.69271 1.000 27.63609 ? 121 GLU A CD   1 
ATOM   1524 O  OE1  . GLU A 1 98  ? -22.27563 -0.27041  25.04799 1.000 25.52601 ? 121 GLU A OE1  1 
ATOM   1525 O  OE2  . GLU A 1 98  ? -24.04721 -1.46260  24.59784 1.000 39.08613 ? 121 GLU A OE2  1 
ATOM   1526 H  H    . GLU A 1 98  ? -19.93602 -3.56658  25.96929 1.000 22.15849 ? 121 GLU A H    1 
ATOM   1527 H  HA   . GLU A 1 98  ? -20.04983 -4.08983  23.44047 1.000 24.98793 ? 121 GLU A HA   1 
ATOM   1528 H  HB2  . GLU A 1 98  ? -20.22632 -1.56419  24.70360 1.000 24.56612 ? 121 GLU A HB2  1 
ATOM   1529 H  HB3  . GLU A 1 98  ? -20.55744 -1.77587  23.16380 1.000 24.56612 ? 121 GLU A HB3  1 
ATOM   1530 H  HG2  . GLU A 1 98  ? -22.38301 -2.98759  23.64384 1.000 27.37377 ? 121 GLU A HG2  1 
ATOM   1531 H  HG3  . GLU A 1 98  ? -21.97980 -3.09015  25.17757 1.000 27.37377 ? 121 GLU A HG3  1 
ATOM   1532 N  N    . LEU A 1 99  ? -17.42006 -2.41688  24.23969 1.000 18.71632 ? 122 LEU A N    1 
ATOM   1533 C  CA   . LEU A 1 99  ? -16.09910 -2.05416  23.72102 1.000 16.15018 ? 122 LEU A CA   1 
ATOM   1534 C  C    . LEU A 1 99  ? -15.28670 -3.29457  23.36027 1.000 17.48135 ? 122 LEU A C    1 
ATOM   1535 O  O    . LEU A 1 99  ? -14.58640 -3.31462  22.34071 1.000 18.30920 ? 122 LEU A O    1 
ATOM   1536 C  CB   . LEU A 1 99  ? -15.34463 -1.19098  24.73210 1.000 21.33826 ? 122 LEU A CB   1 
ATOM   1537 C  CG   . LEU A 1 99  ? -16.04221 0.14887   24.90223 1.000 19.36546 ? 122 LEU A CG   1 
ATOM   1538 C  CD1  . LEU A 1 99  ? -15.77379 0.76180   26.24253 1.000 17.45258 ? 122 LEU A CD1  1 
ATOM   1539 C  CD2  . LEU A 1 99  ? -15.57733 1.09238   23.83453 1.000 20.68163 ? 122 LEU A CD2  1 
ATOM   1540 H  H    . LEU A 1 99  ? -17.56338 -2.20315  25.06029 1.000 22.43950 ? 122 LEU A H    1 
ATOM   1541 H  HA   . LEU A 1 99  ? -16.21903 -1.52715  22.91555 1.000 19.36013 ? 122 LEU A HA   1 
ATOM   1542 H  HB2  . LEU A 1 99  ? -15.32151 -1.64163  25.59075 1.000 25.58583 ? 122 LEU A HB2  1 
ATOM   1543 H  HB3  . LEU A 1 99  ? -14.44133 -1.03413  24.41533 1.000 25.58583 ? 122 LEU A HB3  1 
ATOM   1544 H  HG   . LEU A 1 99  ? -16.99821 0.00010   24.83274 1.000 23.21847 ? 122 LEU A HG   1 
ATOM   1545 H  HD11 . LEU A 1 99  ? -16.19760 1.63343   26.28177 1.000 20.92302 ? 122 LEU A HD11 1 
ATOM   1546 H  HD12 . LEU A 1 99  ? -16.13846 0.18533   26.93216 1.000 20.92302 ? 122 LEU A HD12 1 
ATOM   1547 H  HD13 . LEU A 1 99  ? -14.81554 0.85428   26.36130 1.000 20.92302 ? 122 LEU A HD13 1 
ATOM   1548 H  HD21 . LEU A 1 99  ? -16.12630 1.89172   23.85857 1.000 24.79788 ? 122 LEU A HD21 1 
ATOM   1549 H  HD22 . LEU A 1 99  ? -14.64965 1.32314   23.99907 1.000 24.79788 ? 122 LEU A HD22 1 
ATOM   1550 H  HD23 . LEU A 1 99  ? -15.66216 0.65869   22.97105 1.000 24.79788 ? 122 LEU A HD23 1 
ATOM   1551 N  N    . SER A 1 100 ? -15.35939 -4.34042  24.18169 1.000 17.29154 ? 123 SER A N    1 
ATOM   1552 C  CA   . SER A 1 100 ? -14.65978 -5.57757  23.87219 1.000 17.45722 ? 123 SER A CA   1 
ATOM   1553 C  C    . SER A 1 100 ? -15.14021 -6.13802  22.54391 1.000 18.72660 ? 123 SER A C    1 
ATOM   1554 O  O    . SER A 1 100 ? -14.33649 -6.45206  21.65661 1.000 17.62656 ? 123 SER A O    1 
ATOM   1555 C  CB   . SER A 1 100 ? -14.87637 -6.60384  24.99667 1.000 16.26603 ? 123 SER A CB   1 
ATOM   1556 O  OG   . SER A 1 100 ? -14.25733 -6.18206  26.21285 1.000 16.46634 ? 123 SER A OG   1 
ATOM   1557 H  H    . SER A 1 100 ? -15.80391 -4.35695  24.91771 1.000 20.72977 ? 123 SER A H    1 
ATOM   1558 H  HA   . SER A 1 100 ? -13.70855 -5.39796  23.81055 1.000 20.92858 ? 123 SER A HA   1 
ATOM   1559 H  HB2  . SER A 1 100 ? -15.82891 -6.70618  25.14868 1.000 19.49916 ? 123 SER A HB2  1 
ATOM   1560 H  HB3  . SER A 1 100 ? -14.49063 -7.45170  24.72604 1.000 19.49916 ? 123 SER A HB3  1 
ATOM   1561 H  HG   . SER A 1 100 ? -14.58195 -5.44813  26.46097 1.000 19.73952 ? 123 SER A HG   1 
ATOM   1562 N  N    . ALA A 1 101 ? -16.46297 -6.24931  22.38370 1.000 15.46415 ? 124 ALA A N    1 
ATOM   1563 C  CA   . ALA A 1 101 ? -17.02022 -6.74193  21.12828 1.000 15.24725 ? 124 ALA A CA   1 
ATOM   1564 C  C    . ALA A 1 101 ? -16.64444 -5.85183  19.94610 1.000 18.54532 ? 124 ALA A C    1 
ATOM   1565 O  O    . ALA A 1 101 ? -16.36916 -6.34745  18.85049 1.000 20.92341 ? 124 ALA A O    1 
ATOM   1566 C  CB   . ALA A 1 101 ? -18.54091 -6.86200  21.25501 1.000 18.83927 ? 124 ALA A CB   1 
ATOM   1567 H  H    . ALA A 1 101 ? -17.04927 -6.04829  22.97990 1.000 18.53690 ? 124 ALA A H    1 
ATOM   1568 H  HA   . ALA A 1 101 ? -16.65451 -7.62268  20.95094 1.000 18.27662 ? 124 ALA A HA   1 
ATOM   1569 H  HB1  . ALA A 1 101 ? -18.90202 -7.19660  20.41922 1.000 22.58704 ? 124 ALA A HB1  1 
ATOM   1570 H  HB2  . ALA A 1 101 ? -18.75021 -7.47683  21.97547 1.000 22.58704 ? 124 ALA A HB2  1 
ATOM   1571 H  HB3  . ALA A 1 101 ? -18.91173 -5.98687  21.44876 1.000 22.58704 ? 124 ALA A HB3  1 
ATOM   1572 N  N    . ALA A 1 102 ? -16.63006 -4.54010  20.13964 1.000 16.12059 ? 125 ALA A N    1 
ATOM   1573 C  CA   . ALA A 1 102 ? -16.29662 -3.64216  19.04558 1.000 15.01219 ? 125 ALA A CA   1 
ATOM   1574 C  C    . ALA A 1 102 ? -14.84634 -3.80521  18.64648 1.000 19.13588 ? 125 ALA A C    1 
ATOM   1575 O  O    . ALA A 1 102 ? -14.50104 -3.79199  17.45241 1.000 16.62188 ? 125 ALA A O    1 
ATOM   1576 C  CB   . ALA A 1 102 ? -16.56127 -2.19530  19.46030 1.000 16.80819 ? 125 ALA A CB   1 
ATOM   1577 H  H    . ALA A 1 102 ? -16.80718 -4.14913  20.88488 1.000 19.32462 ? 125 ALA A H    1 
ATOM   1578 H  HA   . ALA A 1 102 ? -16.85842 -3.84988  18.28260 1.000 17.99455 ? 125 ALA A HA   1 
ATOM   1579 H  HB1  . ALA A 1 102 ? -16.32106 -1.60760  18.72695 1.000 20.14975 ? 125 ALA A HB1  1 
ATOM   1580 H  HB2  . ALA A 1 102 ? -17.50282 -2.09419  19.67044 1.000 20.14975 ? 125 ALA A HB2  1 
ATOM   1581 H  HB3  . ALA A 1 102 ? -16.02399 -1.98713  20.24062 1.000 20.14975 ? 125 ALA A HB3  1 
ATOM   1582 N  N    . ALA A 1 103 ? -13.98087 -3.97511  19.63751 1.000 17.95678 ? 126 ALA A N    1 
ATOM   1583 C  CA   . ALA A 1 103 ? -12.56467 -4.18198  19.33806 1.000 18.65435 ? 126 ALA A CA   1 
ATOM   1584 C  C    . ALA A 1 103 ? -12.34771 -5.49458  18.59521 1.000 16.93292 ? 126 ALA A C    1 
ATOM   1585 O  O    . ALA A 1 103 ? -11.55466 -5.56251  17.65424 1.000 15.23309 ? 126 ALA A O    1 
ATOM   1586 C  CB   . ALA A 1 103 ? -11.77549 -4.15015  20.64841 1.000 15.45571 ? 126 ALA A CB   1 
ATOM   1587 H  H    . ALA A 1 103 ? -14.17926 -3.97556  20.47431 1.000 21.52806 ? 126 ALA A H    1 
ATOM   1588 H  HA   . ALA A 1 103 ? -12.23862 -3.46986  18.76580 1.000 22.36514 ? 126 ALA A HA   1 
ATOM   1589 H  HB1  . ALA A 1 103 ? -10.84149 -4.33093  20.45902 1.000 18.52677 ? 126 ALA A HB1  1 
ATOM   1590 H  HB2  . ALA A 1 103 ? -11.86747 -3.27255  21.05123 1.000 18.52677 ? 126 ALA A HB2  1 
ATOM   1591 H  HB3  . ALA A 1 103 ? -12.12882 -4.82725  21.24640 1.000 18.52677 ? 126 ALA A HB3  1 
ATOM   1592 N  N    . LEU A 1 104 ? -13.03207 -6.54662  19.00884 1.000 19.36721 ? 127 LEU A N    1 
ATOM   1593 C  CA   . LEU A 1 104 ? -12.78122 -7.87093  18.47216 1.000 15.30219 ? 127 LEU A CA   1 
ATOM   1594 C  C    . LEU A 1 104 ? -13.45543 -8.09783  17.12600 1.000 14.56663 ? 127 LEU A C    1 
ATOM   1595 O  O    . LEU A 1 104 ? -12.91846 -8.82941  16.28979 1.000 18.90739 ? 127 LEU A O    1 
ATOM   1596 C  CB   . LEU A 1 104 ? -13.27265 -8.93021  19.46205 1.000 14.85940 ? 127 LEU A CB   1 
ATOM   1597 C  CG   . LEU A 1 104 ? -12.41202 -9.07765  20.70799 1.000 14.01524 ? 127 LEU A CG   1 
ATOM   1598 C  CD1  . LEU A 1 104 ? -12.95813 -10.13461 21.66650 1.000 21.64831 ? 127 LEU A CD1  1 
ATOM   1599 C  CD2  . LEU A 1 104 ? -10.99209 -9.45365  20.27142 1.000 16.37846 ? 127 LEU A CD2  1 
ATOM   1600 H  H    . LEU A 1 104 ? -13.65225 -6.52124  19.60410 1.000 23.22057 ? 127 LEU A H    1 
ATOM   1601 H  HA   . LEU A 1 104 ? -11.82431 -7.97020  18.34812 1.000 18.34254 ? 127 LEU A HA   1 
ATOM   1602 H  HB2  . LEU A 1 104 ? -14.16757 -8.69128  19.75004 1.000 17.81120 ? 127 LEU A HB2  1 
ATOM   1603 H  HB3  . LEU A 1 104 ? -13.28726 -9.78937  19.01202 1.000 17.81120 ? 127 LEU A HB3  1 
ATOM   1604 H  HG   . LEU A 1 104 ? -12.40976 -8.23770  21.19314 1.000 16.79821 ? 127 LEU A HG   1 
ATOM   1605 H  HD11 . LEU A 1 104 ? -12.41241 -10.14589 22.46835 1.000 25.95789 ? 127 LEU A HD11 1 
ATOM   1606 H  HD12 . LEU A 1 104 ? -13.87461 -9.91197  21.89322 1.000 25.95789 ? 127 LEU A HD12 1 
ATOM   1607 H  HD13 . LEU A 1 104 ? -12.92602 -11.00142 21.23232 1.000 25.95789 ? 127 LEU A HD13 1 
ATOM   1608 H  HD21 . LEU A 1 104 ? -10.53601 -9.88019  21.01369 1.000 19.63407 ? 127 LEU A HD21 1 
ATOM   1609 H  HD22 . LEU A 1 104 ? -11.04415 -10.06479 19.51996 1.000 19.63407 ? 127 LEU A HD22 1 
ATOM   1610 H  HD23 . LEU A 1 104 ? -10.51822 -8.64844  20.01071 1.000 19.63407 ? 127 LEU A HD23 1 
ATOM   1611 N  N    . GLN A 1 105 ? -14.62927 -7.51367  16.92947 1.000 17.04249 ? 128 GLN A N    1 
ATOM   1612 C  CA   . GLN A 1 105 ? -15.48163 -7.84987  15.79929 1.000 18.16268 ? 128 GLN A CA   1 
ATOM   1613 C  C    . GLN A 1 105 ? -15.47996 -6.79720  14.70270 1.000 21.23884 ? 128 GLN A C    1 
ATOM   1614 O  O    . GLN A 1 105 ? -15.78221 -7.12396  13.54414 1.000 19.28180 ? 128 GLN A O    1 
ATOM   1615 C  CB   . GLN A 1 105 ? -16.91758 -8.06051  16.27673 1.000 20.07758 ? 128 GLN A CB   1 
ATOM   1616 C  CG   . GLN A 1 105 ? -17.05192 -9.21883  17.27730 1.000 19.69052 ? 128 GLN A CG   1 
ATOM   1617 C  CD   . GLN A 1 105 ? -18.48169 -9.46974  17.65142 1.000 23.45888 ? 128 GLN A CD   1 
ATOM   1618 O  OE1  . GLN A 1 105 ? -19.28645 -8.54480  17.70435 1.000 23.16198 ? 128 GLN A OE1  1 
ATOM   1619 N  NE2  . GLN A 1 105 ? -18.81589 -10.72715 17.91376 1.000 22.41777 ? 128 GLN A NE2  1 
ATOM   1620 H  H    . GLN A 1 105 ? -14.95963 -6.90973  17.44496 1.000 20.43091 ? 128 GLN A H    1 
ATOM   1621 H  HA   . GLN A 1 105 ? -15.16480 -8.67936  15.40881 1.000 21.77513 ? 128 GLN A HA   1 
ATOM   1622 H  HB2  . GLN A 1 105 ? -17.22664 -7.25084  16.71240 1.000 24.07302 ? 128 GLN A HB2  1 
ATOM   1623 H  HB3  . GLN A 1 105 ? -17.47822 -8.25975  15.51064 1.000 24.07302 ? 128 GLN A HB3  1 
ATOM   1624 H  HG2  . GLN A 1 105 ? -16.69561 -10.02827 16.87886 1.000 23.60854 ? 128 GLN A HG2  1 
ATOM   1625 H  HG3  . GLN A 1 105 ? -16.56010 -9.00227  18.08483 1.000 23.60854 ? 128 GLN A HG3  1 
ATOM   1626 H  HE21 . GLN A 1 105 ? -18.22357 -11.34871 17.86462 1.000 26.88124 ? 128 GLN A HE21 1 
ATOM   1627 H  HE22 . GLN A 1 105 ? -19.62476 -10.92033 18.13289 1.000 26.88124 ? 128 GLN A HE22 1 
ATOM   1628 N  N    . TYR A 1 106 ? -15.16507 -5.55378  15.03948 1.000 21.30157 ? 129 TYR A N    1 
ATOM   1629 C  CA   . TYR A 1 106 ? -15.00613 -4.49688  14.05554 1.000 19.35920 ? 129 TYR A CA   1 
ATOM   1630 C  C    . TYR A 1 106 ? -13.61472 -3.89452  14.08901 1.000 20.60193 ? 129 TYR A C    1 
ATOM   1631 O  O    . TYR A 1 106 ? -13.33403 -2.98694  13.31333 1.000 23.62713 ? 129 TYR A O    1 
ATOM   1632 C  CB   . TYR A 1 106 ? -16.06514 -3.41561  14.27361 1.000 15.66549 ? 129 TYR A CB   1 
ATOM   1633 C  CG   . TYR A 1 106 ? -17.46993 -3.91928  14.00343 1.000 23.01690 ? 129 TYR A CG   1 
ATOM   1634 C  CD1  . TYR A 1 106 ? -18.20038 -4.57443  14.99937 1.000 22.43098 ? 129 TYR A CD1  1 
ATOM   1635 C  CD2  . TYR A 1 106 ? -18.04453 -3.77798  12.76247 1.000 29.05076 ? 129 TYR A CD2  1 
ATOM   1636 C  CE1  . TYR A 1 106 ? -19.48085 -5.05472  14.75814 1.000 28.65387 ? 129 TYR A CE1  1 
ATOM   1637 C  CE2  . TYR A 1 106 ? -19.35001 -4.25381  12.50213 1.000 26.56010 ? 129 TYR A CE2  1 
ATOM   1638 C  CZ   . TYR A 1 106 ? -20.04562 -4.90516  13.50060 1.000 28.50511 ? 129 TYR A CZ   1 
ATOM   1639 O  OH   . TYR A 1 106 ? -21.31898 -5.39969  13.26017 1.000 38.14264 ? 129 TYR A OH   1 
ATOM   1640 H  H    . TYR A 1 106 ? -15.03590 -5.29342  15.84888 1.000 25.54180 ? 129 TYR A H    1 
ATOM   1641 H  HA   . TYR A 1 106 ? -15.15015 -4.85226  13.16456 1.000 23.21096 ? 129 TYR A HA   1 
ATOM   1642 H  HB2  . TYR A 1 106 ? -16.02477 -3.11342  15.19445 1.000 18.77851 ? 129 TYR A HB2  1 
ATOM   1643 H  HB3  . TYR A 1 106 ? -15.88964 -2.67428  13.67317 1.000 18.77851 ? 129 TYR A HB3  1 
ATOM   1644 H  HD1  . TYR A 1 106 ? -17.82105 -4.69095  15.84046 1.000 26.89710 ? 129 TYR A HD1  1 
ATOM   1645 H  HD2  . TYR A 1 106 ? -17.56590 -3.36198  12.08220 1.000 34.84083 ? 129 TYR A HD2  1 
ATOM   1646 H  HE1  . TYR A 1 106 ? -19.95759 -5.47490  15.43716 1.000 34.36456 ? 129 TYR A HE1  1 
ATOM   1647 H  HE2  . TYR A 1 106 ? -19.73668 -4.12908  11.66558 1.000 31.85204 ? 129 TYR A HE2  1 
ATOM   1648 H  HH   . TYR A 1 106 ? -21.61847 -5.77057  13.95180 1.000 45.75108 ? 129 TYR A HH   1 
ATOM   1649 N  N    . SER A 1 107 ? -12.74300 -4.36079  14.97479 1.000 18.27461 ? 130 SER A N    1 
ATOM   1650 C  CA   . SER A 1 107 ? -11.37037 -3.86792  15.06669 1.000 20.38953 ? 130 SER A CA   1 
ATOM   1651 C  C    . SER A 1 107 ? -11.34868 -2.37197  15.35782 1.000 18.00098 ? 130 SER A C    1 
ATOM   1652 O  O    . SER A 1 107 ? -10.49284 -1.63548  14.87701 1.000 16.59154 ? 130 SER A O    1 
ATOM   1653 C  CB   . SER A 1 107 ? -10.58476 -4.19363  13.79521 1.000 20.14614 ? 130 SER A CB   1 
ATOM   1654 O  OG   . SER A 1 107 ? -9.21186  -4.33387  14.10278 1.000 20.98591 ? 130 SER A OG   1 
ATOM   1655 H  H    . SER A 1 107 ? -12.92447 -4.97646  15.54717 1.000 21.90945 ? 130 SER A H    1 
ATOM   1656 H  HA   . SER A 1 107 ? -10.92878 -4.31290  15.80688 1.000 24.44736 ? 130 SER A HA   1 
ATOM   1657 H  HB2  . SER A 1 107 ? -10.91485 -5.02469  13.41933 1.000 24.15528 ? 130 SER A HB2  1 
ATOM   1658 H  HB3  . SER A 1 107 ? -10.69734 -3.47264  13.15614 1.000 24.15528 ? 130 SER A HB3  1 
ATOM   1659 H  HG   . SER A 1 107 ? -8.87189  -3.57993  14.24977 1.000 25.16301 ? 130 SER A HG   1 
ATOM   1660 N  N    . ASP A 1 108 ? -12.31695 -1.91145  16.15030 1.000 15.22624 ? 131 ASP A N    1 
ATOM   1661 C  CA   . ASP A 1 108 ? -12.42747 -0.50131  16.47858 1.000 15.09512 ? 131 ASP A CA   1 
ATOM   1662 C  C    . ASP A 1 108 ? -11.25155 -0.08835  17.34925 1.000 17.32725 ? 131 ASP A C    1 
ATOM   1663 O  O    . ASP A 1 108 ? -10.97551 -0.72941  18.37031 1.000 18.71004 ? 131 ASP A O    1 
ATOM   1664 C  CB   . ASP A 1 108 ? -13.78148 -0.26377  17.17479 1.000 18.51394 ? 131 ASP A CB   1 
ATOM   1665 C  CG   . ASP A 1 108 ? -14.08968 1.19992   17.41545 1.000 20.38253 ? 131 ASP A CG   1 
ATOM   1666 O  OD1  . ASP A 1 108 ? -13.37939 1.85276   18.21787 1.000 15.37358 ? 131 ASP A OD1  1 
ATOM   1667 O  OD2  . ASP A 1 108 ? -15.05193 1.71687   16.81068 1.000 20.67974 ? 131 ASP A OD2  1 
ATOM   1668 H  H    . ASP A 1 108 ? -12.92423 -2.40226  16.51074 1.000 18.25141 ? 131 ASP A H    1 
ATOM   1669 H  HA   . ASP A 1 108 ? -12.40044 0.05470   15.68421 1.000 18.09406 ? 131 ASP A HA   1 
ATOM   1670 H  HB2  . ASP A 1 108 ? -14.48770 -0.62800  16.61848 1.000 22.19665 ? 131 ASP A HB2  1 
ATOM   1671 H  HB3  . ASP A 1 108 ? -13.77349 -0.71063  18.03569 1.000 22.19665 ? 131 ASP A HB3  1 
ATOM   1672 N  N    . ASN A 1 109 ? -10.54476 0.98347   16.93573 1.000 17.82131 ? 132 ASN A N    1 
ATOM   1673 C  CA   . ASN A 1 109 ? -9.32779  1.39423   17.63542 1.000 15.57426 ? 132 ASN A CA   1 
ATOM   1674 C  C    . ASN A 1 109 ? -9.61665  2.20931   18.89135 1.000 14.62602 ? 132 ASN A C    1 
ATOM   1675 O  O    . ASN A 1 109 ? -8.79801  2.20571   19.82775 1.000 17.16991 ? 132 ASN A O    1 
ATOM   1676 C  CB   . ASN A 1 109 ? -8.41839  2.19859   16.68721 1.000 19.14149 ? 132 ASN A CB   1 
ATOM   1677 C  CG   . ASN A 1 109 ? -7.55042  1.30558   15.82603 1.000 18.80630 ? 132 ASN A CG   1 
ATOM   1678 O  OD1  . ASN A 1 109 ? -7.41540  0.12227   16.10258 1.000 18.66926 ? 132 ASN A OD1  1 
ATOM   1679 N  ND2  . ASN A 1 109 ? -6.93483  1.87419   14.78402 1.000 19.60551 ? 132 ASN A ND2  1 
ATOM   1680 H  H    . ASN A 1 109 ? -10.75159 1.47702   16.26250 1.000 21.36549 ? 132 ASN A H    1 
ATOM   1681 H  HA   . ASN A 1 109 ? -8.85197  0.59442   17.90893 1.000 18.66903 ? 132 ASN A HA   1 
ATOM   1682 H  HB2  . ASN A 1 109 ? -8.97022  2.73924   16.10062 1.000 22.94971 ? 132 ASN A HB2  1 
ATOM   1683 H  HB3  . ASN A 1 109 ? -7.83601  2.76861   17.21333 1.000 22.94971 ? 132 ASN A HB3  1 
ATOM   1684 H  HD21 . ASN A 1 109 ? -6.43288  1.40096   14.27051 1.000 23.50653 ? 132 ASN A HD21 1 
ATOM   1685 H  HD22 . ASN A 1 109 ? -7.04086  2.71313   14.62737 1.000 23.50653 ? 132 ASN A HD22 1 
ATOM   1686 N  N    . VAL A 1 110 ? -10.74295 2.92634   18.94221 1.000 15.79067 ? 133 VAL A N    1 
ATOM   1687 C  CA   . VAL A 1 110 ? -11.12627 3.59156   20.18504 1.000 18.58870 ? 133 VAL A CA   1 
ATOM   1688 C  C    . VAL A 1 110 ? -11.43494 2.53862   21.24432 1.000 17.15774 ? 133 VAL A C    1 
ATOM   1689 O  O    . VAL A 1 110 ? -10.99171 2.63089   22.39975 1.000 16.77653 ? 133 VAL A O    1 
ATOM   1690 C  CB   . VAL A 1 110 ? -12.34259 4.51772   19.97180 1.000 15.09735 ? 133 VAL A CB   1 
ATOM   1691 C  CG1  . VAL A 1 110 ? -12.75740 5.15559   21.33341 1.000 15.08521 ? 133 VAL A CG1  1 
ATOM   1692 C  CG2  . VAL A 1 110 ? -12.04102 5.58857   18.96058 1.000 20.41400 ? 133 VAL A CG2  1 
ATOM   1693 H  H    . VAL A 1 110 ? -11.28786 3.03946   18.28655 1.000 18.92873 ? 133 VAL A H    1 
ATOM   1694 H  HA   . VAL A 1 110 ? -10.38392 4.14280   20.47820 1.000 22.28637 ? 133 VAL A HA   1 
ATOM   1695 H  HB   . VAL A 1 110 ? -13.08179 3.99263   19.62717 1.000 18.09674 ? 133 VAL A HB   1 
ATOM   1696 H  HG11 . VAL A 1 110 ? -13.41680 5.84795   21.16994 1.000 18.08218 ? 133 VAL A HG11 1 
ATOM   1697 H  HG12 . VAL A 1 110 ? -13.13498 4.46697   21.90274 1.000 18.08218 ? 133 VAL A HG12 1 
ATOM   1698 H  HG13 . VAL A 1 110 ? -11.97236 5.53929   21.75458 1.000 18.08218 ? 133 VAL A HG13 1 
ATOM   1699 H  HG21 . VAL A 1 110 ? -12.81010 6.17447   18.88217 1.000 24.47672 ? 133 VAL A HG21 1 
ATOM   1700 H  HG22 . VAL A 1 110 ? -11.26855 6.09464   19.25736 1.000 24.47672 ? 133 VAL A HG22 1 
ATOM   1701 H  HG23 . VAL A 1 110 ? -11.85439 5.17142   18.10498 1.000 24.47672 ? 133 VAL A HG23 1 
ATOM   1702 N  N    . ALA A 1 111 ? -12.18533 1.50808   20.84739 1.000 17.73174 ? 134 ALA A N    1 
ATOM   1703 C  CA   . ALA A 1 111 ? -12.51293 0.40520   21.73974 1.000 16.30171 ? 134 ALA A CA   1 
ATOM   1704 C  C    . ALA A 1 111 ? -11.25132 -0.21042  22.33138 1.000 17.12545 ? 134 ALA A C    1 
ATOM   1705 O  O    . ALA A 1 111 ? -11.17397 -0.44070  23.54563 1.000 16.05322 ? 134 ALA A O    1 
ATOM   1706 C  CB   . ALA A 1 111 ? -13.32686 -0.65480  20.99022 1.000 19.60639 ? 134 ALA A CB   1 
ATOM   1707 H  H    . ALA A 1 111 ? -12.51840 1.42595   20.05877 1.000 21.25801 ? 134 ALA A H    1 
ATOM   1708 H  HA   . ALA A 1 111 ? -13.05801 0.74314   22.46746 1.000 19.54197 ? 134 ALA A HA   1 
ATOM   1709 H  HB1  . ALA A 1 111 ? -13.55020 -1.37296  21.60281 1.000 23.50759 ? 134 ALA A HB1  1 
ATOM   1710 H  HB2  . ALA A 1 111 ? -14.13804 -0.24700  20.64878 1.000 23.50759 ? 134 ALA A HB2  1 
ATOM   1711 H  HB3  . ALA A 1 111 ? -12.79558 -0.99984  20.25565 1.000 23.50759 ? 134 ALA A HB3  1 
ATOM   1712 N  N    . MET A 1 112 ? -10.24079 -0.46588  21.48780 1.000 15.08638 ? 135 MET A N    1 
ATOM   1713 C  CA   . MET A 1 112 ? -8.96443  -0.98517  21.98487 1.000 16.30952 ? 135 MET A CA   1 
ATOM   1714 C  C    . MET A 1 112 ? -8.34120  -0.04277  23.01386 1.000 14.68654 ? 135 MET A C    1 
ATOM   1715 O  O    . MET A 1 112 ? -7.86901  -0.48567  24.07203 1.000 15.25632 ? 135 MET A O    1 
ATOM   1716 C  CB   . MET A 1 112 ? -8.01267  -1.22014  20.80779 1.000 16.52519 ? 135 MET A CB   1 
ATOM   1717 C  CG   . MET A 1 112 ? -6.57604  -1.60386  21.21868 1.000 15.07153 ? 135 MET A CG   1 
ATOM   1718 S  SD   . MET A 1 112 ? -6.50965  -3.11275  22.18504 1.000 16.23767 ? 135 MET A SD   1 
ATOM   1719 C  CE   . MET A 1 112 ? -4.81862  -3.61308  21.73874 1.000 17.57319 ? 135 MET A CE   1 
ATOM   1720 H  H    . MET A 1 112 ? -10.27014 -0.34823  20.63639 1.000 18.08358 ? 135 MET A H    1 
ATOM   1721 H  HA   . MET A 1 112 ? -9.12357  -1.83921  22.41636 1.000 19.55134 ? 135 MET A HA   1 
ATOM   1722 H  HB2  . MET A 1 112 ? -8.36523  -1.94181  20.26393 1.000 19.81015 ? 135 MET A HB2  1 
ATOM   1723 H  HB3  . MET A 1 112 ? -7.96063  -0.40516  20.28433 1.000 19.81015 ? 135 MET A HB3  1 
ATOM   1724 H  HG2  . MET A 1 112 ? -6.04341  -1.73634  20.41890 1.000 18.06576 ? 135 MET A HG2  1 
ATOM   1725 H  HG3  . MET A 1 112 ? -6.19868  -0.88823  21.75382 1.000 18.06576 ? 135 MET A HG3  1 
ATOM   1726 H  HE1  . MET A 1 112 ? -4.52899  -4.31783  22.33902 1.000 21.06774 ? 135 MET A HE1  1 
ATOM   1727 H  HE2  . MET A 1 112 ? -4.81581  -3.93579  20.82400 1.000 21.06774 ? 135 MET A HE2  1 
ATOM   1728 H  HE3  . MET A 1 112 ? -4.23036  -2.84619  21.82075 1.000 21.06774 ? 135 MET A HE3  1 
ATOM   1729 N  N    . ASN A 1 113 ? -8.32387  1.26000   22.73189 1.000 14.52185 ? 136 ASN A N    1 
ATOM   1730 C  CA   . ASN A 1 113 ? -7.70724  2.19097   23.67383 1.000 17.24420 ? 136 ASN A CA   1 
ATOM   1731 C  C    . ASN A 1 113 ? -8.44154  2.20412   25.00967 1.000 15.59647 ? 136 ASN A C    1 
ATOM   1732 O  O    . ASN A 1 113 ? -7.81649  2.38326   26.05835 1.000 16.59411 ? 136 ASN A O    1 
ATOM   1733 C  CB   . ASN A 1 113 ? -7.66346  3.59622   23.08488 1.000 14.58918 ? 136 ASN A CB   1 
ATOM   1734 C  CG   . ASN A 1 113 ? -6.43753  3.80563   22.17181 1.000 13.85296 ? 136 ASN A CG   1 
ATOM   1735 O  OD1  . ASN A 1 113 ? -5.53567  2.97180   22.14692 1.000 16.83939 ? 136 ASN A OD1  1 
ATOM   1736 N  ND2  . ASN A 1 113 ? -6.39822  4.92544   21.46042 1.000 15.69003 ? 136 ASN A ND2  1 
ATOM   1737 H  H    . ASN A 1 113 ? -8.65237  1.61994   22.02328 1.000 17.40614 ? 136 ASN A H    1 
ATOM   1738 H  HA   . ASN A 1 113 ? -6.79332  1.90674   23.83151 1.000 20.67295 ? 136 ASN A HA   1 
ATOM   1739 H  HB2  . ASN A 1 113 ? -8.46323  3.74525   22.55661 1.000 17.48693 ? 136 ASN A HB2  1 
ATOM   1740 H  HB3  . ASN A 1 113 ? -7.61727  4.24274   23.80653 1.000 17.48693 ? 136 ASN A HB3  1 
ATOM   1741 H  HD21 . ASN A 1 113 ? -5.73211  5.08048   20.93902 1.000 18.80795 ? 136 ASN A HD21 1 
ATOM   1742 H  HD22 . ASN A 1 113 ? -7.03886  5.49599   21.52087 1.000 18.80795 ? 136 ASN A HD22 1 
ATOM   1743 N  N    . LYS A 1 114 ? -9.76345  2.02501   24.99604 1.000 14.87743 ? 137 LYS A N    1 
ATOM   1744 C  CA   . LYS A 1 114 ? -10.49032 1.97592   26.25839 1.000 16.10656 ? 137 LYS A CA   1 
ATOM   1745 C  C    . LYS A 1 114 ? -10.17711 0.69902   27.02612 1.000 17.26619 ? 137 LYS A C    1 
ATOM   1746 O  O    . LYS A 1 114 ? -10.07302 0.72383   28.26490 1.000 18.21567 ? 137 LYS A O    1 
ATOM   1747 C  CB   . LYS A 1 114 ? -11.98696 2.11582   25.99382 1.000 17.49311 ? 137 LYS A CB   1 
ATOM   1748 C  CG   . LYS A 1 114 ? -12.40412 3.46014   25.37882 1.000 20.31545 ? 137 LYS A CG   1 
ATOM   1749 C  CD   . LYS A 1 114 ? -11.95069 4.64613   26.21672 1.000 23.99808 ? 137 LYS A CD   1 
ATOM   1750 C  CE   . LYS A 1 114 ? -12.54992 5.96656   25.78317 1.000 24.71412 ? 137 LYS A CE   1 
ATOM   1751 N  NZ   . LYS A 1 114 ? -11.97539 7.03694   26.64959 1.000 22.39280 ? 137 LYS A NZ   1 
ATOM   1752 H  H    . LYS A 1 114 ? -10.24622 1.93235   24.29038 1.000 17.83283 ? 137 LYS A H    1 
ATOM   1753 H  HA   . LYS A 1 114 ? -10.21828 2.72137   26.81624 1.000 19.30779 ? 137 LYS A HA   1 
ATOM   1754 H  HB2  . LYS A 1 114 ? -12.25846 1.41610   25.37935 1.000 20.97165 ? 137 LYS A HB2  1 
ATOM   1755 H  HB3  . LYS A 1 114 ? -12.45944 2.01990   26.83552 1.000 20.97165 ? 137 LYS A HB3  1 
ATOM   1756 H  HG2  . LYS A 1 114 ? -12.00625 3.54398   24.49816 1.000 24.35846 ? 137 LYS A HG2  1 
ATOM   1757 H  HG3  . LYS A 1 114 ? -13.37118 3.49200   25.31037 1.000 24.35846 ? 137 LYS A HG3  1 
ATOM   1758 H  HD2  . LYS A 1 114 ? -12.20910 4.49378   27.13917 1.000 28.77761 ? 137 LYS A HD2  1 
ATOM   1759 H  HD3  . LYS A 1 114 ? -10.98609 4.72435   26.15099 1.000 28.77761 ? 137 LYS A HD3  1 
ATOM   1760 H  HE2  . LYS A 1 114 ? -12.32450 6.14867   24.85747 1.000 29.63686 ? 137 LYS A HE2  1 
ATOM   1761 H  HE3  . LYS A 1 114 ? -13.51356 5.94895   25.89268 1.000 29.63686 ? 137 LYS A HE3  1 
ATOM   1762 H  HZ1  . LYS A 1 114 ? -11.09035 7.05990   26.55858 1.000 26.85128 ? 137 LYS A HZ1  1 
ATOM   1763 H  HZ2  . LYS A 1 114 ? -12.31019 7.82840   26.41806 1.000 26.85128 ? 137 LYS A HZ2  1 
ATOM   1764 H  HZ3  . LYS A 1 114 ? -12.17401 6.87760   27.50239 1.000 26.85128 ? 137 LYS A HZ3  1 
ATOM   1765 N  N    . LEU A 1 115 ? -10.05726 -0.43485  26.33057 1.000 16.35879 ? 138 LEU A N    1 
ATOM   1766 C  CA   . LEU A 1 115 ? -9.67982  -1.66584  27.02298 1.000 16.49163 ? 138 LEU A CA   1 
ATOM   1767 C  C    . LEU A 1 115 ? -8.30421  -1.50827  27.63377 1.000 16.09913 ? 138 LEU A C    1 
ATOM   1768 O  O    . LEU A 1 115 ? -8.07903  -1.84600  28.80332 1.000 17.84607 ? 138 LEU A O    1 
ATOM   1769 C  CB   . LEU A 1 115 ? -9.67483  -2.83782  26.04727 1.000 18.14710 ? 138 LEU A CB   1 
ATOM   1770 C  CG   . LEU A 1 115 ? -10.98274 -3.13136  25.32758 1.000 15.17297 ? 138 LEU A CG   1 
ATOM   1771 C  CD1  . LEU A 1 115 ? -10.72953 -4.26967  24.35818 1.000 17.82823 ? 138 LEU A CD1  1 
ATOM   1772 C  CD2  . LEU A 1 115 ? -12.07921 -3.47744  26.32275 1.000 17.60556 ? 138 LEU A CD2  1 
ATOM   1773 H  H    . LEU A 1 115 ? -10.18509 -0.51481  25.48389 1.000 19.61047 ? 138 LEU A H    1 
ATOM   1774 H  HA   . LEU A 1 115 ? -10.32874 -1.85217  27.71945 1.000 19.76988 ? 138 LEU A HA   1 
ATOM   1775 H  HB2  . LEU A 1 115 ? -9.00907  -2.65747  25.36526 1.000 21.75644 ? 138 LEU A HB2  1 
ATOM   1776 H  HB3  . LEU A 1 115 ? -9.43587  -3.63796  26.54080 1.000 21.75644 ? 138 LEU A HB3  1 
ATOM   1777 H  HG   . LEU A 1 115 ? -11.29466 -2.35404  24.83832 1.000 18.18749 ? 138 LEU A HG   1 
ATOM   1778 H  HD11 . LEU A 1 115 ? -11.55309 -4.47293  23.88772 1.000 21.37380 ? 138 LEU A HD11 1 
ATOM   1779 H  HD12 . LEU A 1 115 ? -10.04534 -3.99966  23.72582 1.000 21.37380 ? 138 LEU A HD12 1 
ATOM   1780 H  HD13 . LEU A 1 115 ? -10.43196 -5.04760  24.85537 1.000 21.37380 ? 138 LEU A HD13 1 
ATOM   1781 H  HD21 . LEU A 1 115 ? -12.90680 -3.63013  25.84038 1.000 21.10659 ? 138 LEU A HD21 1 
ATOM   1782 H  HD22 . LEU A 1 115 ? -11.82537 -4.27917  26.80617 1.000 21.10659 ? 138 LEU A HD22 1 
ATOM   1783 H  HD23 . LEU A 1 115 ? -12.18859 -2.73865  26.94172 1.000 21.10659 ? 138 LEU A HD23 1 
ATOM   1784 N  N    . ILE A 1 116 ? -7.36401  -0.99720  26.83435 1.000 18.56541 ? 139 ILE A N    1 
ATOM   1785 C  CA   . ILE A 1 116 ? -6.01655  -0.74800  27.32494 1.000 17.22948 ? 139 ILE A CA   1 
ATOM   1786 C  C    . ILE A 1 116 ? -6.06132  0.15354   28.55289 1.000 18.48988 ? 139 ILE A C    1 
ATOM   1787 O  O    . ILE A 1 116 ? -5.43173  -0.12961  29.57793 1.000 18.19004 ? 139 ILE A O    1 
ATOM   1788 C  CB   . ILE A 1 116 ? -5.14419  -0.12399  26.22282 1.000 14.68278 ? 139 ILE A CB   1 
ATOM   1789 C  CG1  . ILE A 1 116 ? -4.83101  -1.14031  25.13501 1.000 14.80444 ? 139 ILE A CG1  1 
ATOM   1790 C  CG2  . ILE A 1 116 ? -3.86387  0.44324   26.85569 1.000 16.68817 ? 139 ILE A CG2  1 
ATOM   1791 C  CD1  . ILE A 1 116 ? -4.18493  -0.50971  23.91280 1.000 18.15730 ? 139 ILE A CD1  1 
ATOM   1792 H  H    . ILE A 1 116 ? -7.48413  -0.78850  26.00875 1.000 22.25841 ? 139 ILE A H    1 
ATOM   1793 H  HA   . ILE A 1 116 ? -5.62528  -1.59858  27.57853 1.000 20.65530 ? 139 ILE A HA   1 
ATOM   1794 H  HB   . ILE A 1 116 ? -5.63190  0.59939   25.79885 1.000 17.59925 ? 139 ILE A HB   1 
ATOM   1795 H  HG12 . ILE A 1 116 ? -4.21929  -1.80439  25.48953 1.000 17.74525 ? 139 ILE A HG12 1 
ATOM   1796 H  HG13 . ILE A 1 116 ? -5.65582  -1.56595  24.85319 1.000 17.74525 ? 139 ILE A HG13 1 
ATOM   1797 H  HG21 . ILE A 1 116 ? -3.20067  0.57732   26.16065 1.000 20.00572 ? 139 ILE A HG21 1 
ATOM   1798 H  HG22 . ILE A 1 116 ? -4.07082  1.28909   27.28304 1.000 20.00572 ? 139 ILE A HG22 1 
ATOM   1799 H  HG23 . ILE A 1 116 ? -3.53081  -0.18697  27.51356 1.000 20.00572 ? 139 ILE A HG23 1 
ATOM   1800 H  HD11 . ILE A 1 116 ? -4.25832  -1.12306  23.16493 1.000 21.76868 ? 139 ILE A HD11 1 
ATOM   1801 H  HD12 . ILE A 1 116 ? -4.64286  0.32007   23.70624 1.000 21.76868 ? 139 ILE A HD12 1 
ATOM   1802 H  HD13 . ILE A 1 116 ? -3.25078  -0.33295  24.10519 1.000 21.76868 ? 139 ILE A HD13 1 
ATOM   1803 N  N    . ALA A 1 117 ? -6.75142  1.29438   28.44921 1.000 18.60382 ? 140 ALA A N    1 
ATOM   1804 C  CA   . ALA A 1 117 ? -6.76029  2.22177   29.57850 1.000 15.61654 ? 140 ALA A CA   1 
ATOM   1805 C  C    . ALA A 1 117 ? -7.34521  1.56439   30.81630 1.000 16.11241 ? 140 ALA A C    1 
ATOM   1806 O  O    . ALA A 1 117 ? -6.85722  1.76688   31.94797 1.000 18.47610 ? 140 ALA A O    1 
ATOM   1807 C  CB   . ALA A 1 117 ? -7.54861  3.48555   29.21204 1.000 18.65368 ? 140 ALA A CB   1 
ATOM   1808 H  H    . ALA A 1 117 ? -7.20451  1.54364   27.76206 1.000 22.30450 ? 140 ALA A H    1 
ATOM   1809 H  HA   . ALA A 1 117 ? -5.84889  2.48604   29.77952 1.000 18.71977 ? 140 ALA A HA   1 
ATOM   1810 H  HB1  . ALA A 1 117 ? -7.56834  4.07896   29.97910 1.000 22.36434 ? 140 ALA A HB1  1 
ATOM   1811 H  HB2  . ALA A 1 117 ? -7.11211  3.92461   28.46532 1.000 22.36434 ? 140 ALA A HB2  1 
ATOM   1812 H  HB3  . ALA A 1 117 ? -8.45227  3.23365   28.96538 1.000 22.36434 ? 140 ALA A HB3  1 
ATOM   1813 N  N    . HIS A 1 118 ? -8.40978  0.80103   30.62008 1.000 17.50651 ? 141 HIS A N    1 
ATOM   1814 C  CA   . HIS A 1 118 ? -9.12213  0.25044   31.74795 1.000 17.89349 ? 141 HIS A CA   1 
ATOM   1815 C  C    . HIS A 1 118 ? -8.24088  -0.68997  32.54783 1.000 21.62146 ? 141 HIS A C    1 
ATOM   1816 O  O    . HIS A 1 118 ? -8.26918  -0.66437  33.77957 1.000 26.52927 ? 141 HIS A O    1 
ATOM   1817 C  CB   . HIS A 1 118 ? -10.38108 -0.47030  31.32132 1.000 25.18744 ? 141 HIS A CB   1 
ATOM   1818 C  CG   . HIS A 1 118 ? -11.12063 -1.01397  32.48982 1.000 31.28076 ? 141 HIS A CG   1 
ATOM   1819 N  ND1  . HIS A 1 118 ? -11.91889 -0.22261  33.28895 1.000 40.11139 ? 141 HIS A ND1  1 
ATOM   1820 C  CD2  . HIS A 1 118 ? -11.11372 -2.24309  33.05936 1.000 46.31204 ? 141 HIS A CD2  1 
ATOM   1821 C  CE1  . HIS A 1 118 ? -12.40915 -0.95072  34.27543 1.000 40.07285 ? 141 HIS A CE1  1 
ATOM   1822 N  NE2  . HIS A 1 118 ? -11.93735 -2.18153  34.15798 1.000 41.37233 ? 141 HIS A NE2  1 
ATOM   1823 H  H    . HIS A 1 118 ? -8.73316  0.59156   29.85122 1.000 20.98773 ? 141 HIS A H    1 
ATOM   1824 H  HA   . HIS A 1 118 ? -9.39024  0.99423   32.30992 1.000 21.45210 ? 141 HIS A HA   1 
ATOM   1825 H  HB2  . HIS A 1 118 ? -10.96226 0.14952   30.85340 1.000 30.20485 ? 141 HIS A HB2  1 
ATOM   1826 H  HB3  . HIS A 1 118 ? -10.14558 -1.20886  30.73826 1.000 30.20485 ? 141 HIS A HB3  1 
ATOM   1827 H  HD1  . HIS A 1 118 ? -12.07322 0.61420   33.16428 1.000 48.11359 ? 141 HIS A HD1  1 
ATOM   1828 H  HD2  . HIS A 1 118 ? -10.64128 -2.98738  32.76316 1.000 55.55437 ? 141 HIS A HD2  1 
ATOM   1829 H  HE1  . HIS A 1 118 ? -12.98707 -0.65004  34.93913 1.000 48.06734 ? 141 HIS A HE1  1 
ATOM   1830 N  N    . VAL A 1 119 ? -7.40512  -1.49206  31.88049 1.000 16.67826 ? 142 VAL A N    1 
ATOM   1831 C  CA   . VAL A 1 119 ? -6.63040  -2.48304  32.62741 1.000 20.37392 ? 142 VAL A CA   1 
ATOM   1832 C  C    . VAL A 1 119 ? -5.30266  -1.93344  33.11777 1.000 21.76913 ? 142 VAL A C    1 
ATOM   1833 O  O    . VAL A 1 119 ? -4.58847  -2.63463  33.84967 1.000 23.53998 ? 142 VAL A O    1 
ATOM   1834 C  CB   . VAL A 1 119 ? -6.39241  -3.77757  31.82172 1.000 27.47619 ? 142 VAL A CB   1 
ATOM   1835 C  CG1  . VAL A 1 119 ? -7.71307  -4.43630  31.47341 1.000 29.58259 ? 142 VAL A CG1  1 
ATOM   1836 C  CG2  . VAL A 1 119 ? -5.60800  -3.52780  30.55386 1.000 22.13102 ? 142 VAL A CG2  1 
ATOM   1837 H  H    A VAL A 1 119 ? -7.27551  -1.48113  31.03038 0.540 19.99383 ? 142 VAL A H    1 
ATOM   1838 H  H    B VAL A 1 119 ? -7.27551  -1.48113  31.03038 0.460 19.99383 ? 142 VAL A H    1 
ATOM   1839 H  HA   . VAL A 1 119 ? -7.16425  -2.72224  33.40116 1.000 24.42862 ? 142 VAL A HA   1 
ATOM   1840 H  HB   . VAL A 1 119 ? -5.86874  -4.37152  32.38199 1.000 32.95135 ? 142 VAL A HB   1 
ATOM   1841 H  HG11 . VAL A 1 119 ? -7.53744  -5.27552  31.01981 1.000 35.47903 ? 142 VAL A HG11 1 
ATOM   1842 H  HG12 . VAL A 1 119 ? -8.20974  -4.59953  32.29046 1.000 35.47903 ? 142 VAL A HG12 1 
ATOM   1843 H  HG13 . VAL A 1 119 ? -8.21715  -3.84540  30.89234 1.000 35.47903 ? 142 VAL A HG13 1 
ATOM   1844 H  HG21 . VAL A 1 119 ? -5.57526  -4.34741  30.03612 1.000 26.53715 ? 142 VAL A HG21 1 
ATOM   1845 H  HG22 . VAL A 1 119 ? -6.04799  -2.83084  30.04243 1.000 26.53715 ? 142 VAL A HG22 1 
ATOM   1846 H  HG23 . VAL A 1 119 ? -4.70916  -3.24859  30.78844 1.000 26.53715 ? 142 VAL A HG23 1 
ATOM   1847 N  N    . GLY A 1 120 ? -4.95358  -0.69554  32.76135 1.000 20.52287 ? 143 GLY A N    1 
ATOM   1848 C  CA   . GLY A 1 120 ? -3.75830  -0.07498  33.28492 1.000 22.21966 ? 143 GLY A CA   1 
ATOM   1849 C  C    . GLY A 1 120 ? -2.70987  0.28431   32.24153 1.000 20.93565 ? 143 GLY A C    1 
ATOM   1850 O  O    . GLY A 1 120 ? -1.60514  0.67434   32.59939 1.000 24.63538 ? 143 GLY A O    1 
ATOM   1851 H  H    . GLY A 1 120 ? -5.39899  -0.20122  32.21650 1.000 24.60737 ? 143 GLY A H    1 
ATOM   1852 H  HA2  . GLY A 1 120 ? -4.00827  0.74172   33.74471 1.000 26.64351 ? 143 GLY A HA2  1 
ATOM   1853 H  HA3  . GLY A 1 120 ? -3.34617  -0.68143  33.91995 1.000 26.64351 ? 143 GLY A HA3  1 
ATOM   1854 N  N    . GLY A 1 121 ? -3.02130  0.18745   30.96059 1.000 16.05011 ? 144 GLY A N    1 
ATOM   1855 C  CA   . GLY A 1 121 ? -2.06553  0.56818   29.94580 1.000 16.68644 ? 144 GLY A CA   1 
ATOM   1856 C  C    . GLY A 1 121 ? -1.34321  -0.61356  29.33553 1.000 15.89056 ? 144 GLY A C    1 
ATOM   1857 O  O    . GLY A 1 121 ? -1.53249  -1.77083  29.73171 1.000 21.15739 ? 144 GLY A O    1 
ATOM   1858 H  H    . GLY A 1 121 ? -3.77560  -0.09441  30.65863 1.000 19.24006 ? 144 GLY A H    1 
ATOM   1859 H  HA2  . GLY A 1 121 ? -2.52710  1.04027   29.23518 1.000 20.00365 ? 144 GLY A HA2  1 
ATOM   1860 H  HA3  . GLY A 1 121 ? -1.40282  1.15787   30.33818 1.000 20.00365 ? 144 GLY A HA3  1 
ATOM   1861 N  N    . PRO A 1 122 ? -0.50441  -0.33898  28.32536 1.000 17.69596 ? 145 PRO A N    1 
ATOM   1862 C  CA   . PRO A 1 122 ? 0.10650   -1.44176  27.58028 1.000 16.01737 ? 145 PRO A CA   1 
ATOM   1863 C  C    . PRO A 1 122 ? 0.96601   -2.34863  28.43928 1.000 16.72583 ? 145 PRO A C    1 
ATOM   1864 O  O    . PRO A 1 122 ? 0.98941   -3.56409  28.18666 1.000 19.00529 ? 145 PRO A O    1 
ATOM   1865 C  CB   . PRO A 1 122 ? 0.95185   -0.73649  26.50342 1.000 18.06622 ? 145 PRO A CB   1 
ATOM   1866 C  CG   . PRO A 1 122 ? 0.27782   0.62865   26.30085 1.000 15.40797 ? 145 PRO A CG   1 
ATOM   1867 C  CD   . PRO A 1 122 ? -0.21175  0.97725   27.73246 1.000 19.17170 ? 145 PRO A CD   1 
ATOM   1868 H  HA   . PRO A 1 122 ? -0.59100  -1.96108  27.15051 1.000 19.20076 ? 145 PRO A HA   1 
ATOM   1869 H  HB2  . PRO A 1 122 ? 1.86379   -0.63043  26.81649 1.000 21.65938 ? 145 PRO A HB2  1 
ATOM   1870 H  HB3  . PRO A 1 122 ? 0.94075   -1.25433  25.68329 1.000 21.65938 ? 145 PRO A HB3  1 
ATOM   1871 H  HG2  . PRO A 1 122 ? 0.91868   1.28009   25.97554 1.000 18.46948 ? 145 PRO A HG2  1 
ATOM   1872 H  HG3  . PRO A 1 122 ? -0.46349  0.55377   25.67975 1.000 18.46948 ? 145 PRO A HG3  1 
ATOM   1873 H  HD2  . PRO A 1 122 ? 0.48293   1.43358   28.23254 1.000 22.98596 ? 145 PRO A HD2  1 
ATOM   1874 H  HD3  . PRO A 1 122 ? -1.01122  1.52556   27.69919 1.000 22.98596 ? 145 PRO A HD3  1 
ATOM   1875 N  N    . ALA A 1 123 ? 1.65293   -1.81585  29.45090 1.000 19.49976 ? 146 ALA A N    1 
ATOM   1876 C  CA   . ALA A 1 123 ? 2.46304   -2.67793  30.30232 1.000 19.17060 ? 146 ALA A CA   1 
ATOM   1877 C  C    . ALA A 1 123 ? 1.60143   -3.61261  31.15239 1.000 18.05980 ? 146 ALA A C    1 
ATOM   1878 O  O    . ALA A 1 123 ? 2.07855   -4.65239  31.61153 1.000 17.31220 ? 146 ALA A O    1 
ATOM   1879 C  CB   . ALA A 1 123 ? 3.36900   -1.85917  31.22836 1.000 21.59426 ? 146 ALA A CB   1 
ATOM   1880 H  H    . ALA A 1 123 ? 1.66531   -0.98131  29.65822 1.000 23.37964 ? 146 ALA A H    1 
ATOM   1881 H  HA   . ALA A 1 123 ? 3.02791   -3.20701  29.71761 1.000 22.98463 ? 146 ALA A HA   1 
ATOM   1882 H  HB1  . ALA A 1 123 ? 3.90674   -2.46569  31.76117 1.000 25.89303 ? 146 ALA A HB1  1 
ATOM   1883 H  HB2  . ALA A 1 123 ? 3.94407   -1.29422  30.68889 1.000 25.89303 ? 146 ALA A HB2  1 
ATOM   1884 H  HB3  . ALA A 1 123 ? 2.81627   -1.31146  31.80750 1.000 25.89303 ? 146 ALA A HB3  1 
ATOM   1885 N  N    . SER A 1 124 ? 0.36205   -3.22426  31.44206 1.000 20.63098 ? 147 SER A N    1 
ATOM   1886 C  CA   A SER A 1 124 ? -0.52791  -4.12579  32.16253 0.664 18.20963 ? 147 SER A CA   1 
ATOM   1887 C  CA   B SER A 1 124 ? -0.53071  -4.12247  32.16053 0.336 18.26249 ? 147 SER A CA   1 
ATOM   1888 C  C    . SER A 1 124 ? -1.04931  -5.21663  31.24384 1.000 16.12955 ? 147 SER A C    1 
ATOM   1889 O  O    . SER A 1 124 ? -1.21570  -6.36019  31.67660 1.000 19.73464 ? 147 SER A O    1 
ATOM   1890 C  CB   A SER A 1 124 ? -1.69017  -3.35506  32.78398 0.664 19.11516 ? 147 SER A CB   1 
ATOM   1891 C  CB   B SER A 1 124 ? -1.68173  -3.33253  32.77110 0.336 19.18895 ? 147 SER A CB   1 
ATOM   1892 O  OG   A SER A 1 124 ? -2.59504  -4.24902  33.42043 0.664 20.16214 ? 147 SER A OG   1 
ATOM   1893 O  OG   B SER A 1 124 ? -1.17863  -2.39451  33.70482 0.336 18.70012 ? 147 SER A OG   1 
ATOM   1894 H  H    A SER A 1 124 ? 0.02081   -2.46189  31.23726 0.664 24.73710 ? 147 SER A H    1 
ATOM   1895 H  H    B SER A 1 124 ? 0.02194   -2.46132  31.23749 0.336 24.73710 ? 147 SER A H    1 
ATOM   1896 H  HA   A SER A 1 124 ? -0.03412  -4.53818  32.88847 0.664 21.83148 ? 147 SER A HA   1 
ATOM   1897 H  HA   B SER A 1 124 ? -0.04837  -4.54391  32.88897 0.336 21.89491 ? 147 SER A HA   1 
ATOM   1898 H  HB2  A SER A 1 124 ? -1.34268  -2.73314  33.44229 0.664 22.91811 ? 147 SER A HB2  1 
ATOM   1899 H  HB2  B SER A 1 124 ? -2.15477  -2.86119  32.06756 0.336 23.00666 ? 147 SER A HB2  1 
ATOM   1900 H  HB3  A SER A 1 124 ? -2.15961  -2.87166  32.08625 0.664 22.91811 ? 147 SER A HB3  1 
ATOM   1901 H  HB3  B SER A 1 124 ? -2.28386  -3.94329  33.22419 0.336 23.00666 ? 147 SER A HB3  1 
ATOM   1902 H  HG   A SER A 1 124 ? -3.23430  -3.81992  33.75633 0.664 24.17448 ? 147 SER A HG   1 
ATOM   1903 H  HG   B SER A 1 124 ? -1.81182  -2.05247  34.13803 0.336 22.42007 ? 147 SER A HG   1 
ATOM   1904 N  N    . VAL A 1 125 ? -1.31775  -4.88877  29.97673 1.000 15.60788 ? 148 VAL A N    1 
ATOM   1905 C  CA   . VAL A 1 125 ? -1.69679  -5.96340  29.05850 1.000 15.48002 ? 148 VAL A CA   1 
ATOM   1906 C  C    . VAL A 1 125 ? -0.53706  -6.94404  28.93341 1.000 20.56345 ? 148 VAL A C    1 
ATOM   1907 O  O    . VAL A 1 125 ? -0.72495  -8.16808  28.92878 1.000 16.68897 ? 148 VAL A O    1 
ATOM   1908 C  CB   . VAL A 1 125 ? -2.11942  -5.42359  27.67360 1.000 17.15125 ? 148 VAL A CB   1 
ATOM   1909 C  CG1  . VAL A 1 125 ? -2.50083  -6.60373  26.77623 1.000 14.13130 ? 148 VAL A CG1  1 
ATOM   1910 C  CG2  . VAL A 1 125 ? -3.27818  -4.45865  27.80005 1.000 19.05271 ? 148 VAL A CG2  1 
ATOM   1911 H  H    . VAL A 1 125 ? -1.28922  -4.09668  29.64299 1.000 18.70937 ? 148 VAL A H    1 
ATOM   1912 H  HA   . VAL A 1 125 ? -2.47172  -6.41436  29.42866 1.000 18.55595 ? 148 VAL A HA   1 
ATOM   1913 H  HB   . VAL A 1 125 ? -1.38025  -4.93888  27.27412 1.000 20.56142 ? 148 VAL A HB   1 
ATOM   1914 H  HG11 . VAL A 1 125 ? -3.00072  -6.27218  26.01394 1.000 16.93748 ? 148 VAL A HG11 1 
ATOM   1915 H  HG12 . VAL A 1 125 ? -1.69167  -7.04539  26.47441 1.000 16.93748 ? 148 VAL A HG12 1 
ATOM   1916 H  HG13 . VAL A 1 125 ? -3.04615  -7.22398  27.28497 1.000 16.93748 ? 148 VAL A HG13 1 
ATOM   1917 H  HG21 . VAL A 1 125 ? -3.53419  -4.15489  26.91513 1.000 22.84317 ? 148 VAL A HG21 1 
ATOM   1918 H  HG22 . VAL A 1 125 ? -4.02358  -4.91385  28.22203 1.000 22.84317 ? 148 VAL A HG22 1 
ATOM   1919 H  HG23 . VAL A 1 125 ? -3.00224  -3.70309  28.34215 1.000 22.84317 ? 148 VAL A HG23 1 
ATOM   1920 N  N    . THR A 1 126 ? 0.69292   -6.41437  28.86982 1.000 17.80554 ? 149 THR A N    1 
ATOM   1921 C  CA   . THR A 1 126 ? 1.86776   -7.26642  28.79241 1.000 15.42626 ? 149 THR A CA   1 
ATOM   1922 C  C    . THR A 1 126 ? 2.03271   -8.10328  30.05515 1.000 17.65451 ? 149 THR A C    1 
ATOM   1923 O  O    . THR A 1 126 ? 2.42239   -9.26717  29.97767 1.000 15.81118 ? 149 THR A O    1 
ATOM   1924 C  CB   . THR A 1 126 ? 3.11557   -6.41158  28.53822 1.000 19.53149 ? 149 THR A CB   1 
ATOM   1925 O  OG1  . THR A 1 126 ? 2.94484   -5.72834  27.28431 1.000 17.84897 ? 149 THR A OG1  1 
ATOM   1926 C  CG2  . THR A 1 126 ? 4.38832   -7.26372  28.49876 1.000 16.16783 ? 149 THR A CG2  1 
ATOM   1927 H  H    . THR A 1 126 ? 0.86498   -5.57176  28.87036 1.000 21.34656 ? 149 THR A H    1 
ATOM   1928 H  HA   . THR A 1 126 ? 1.76403   -7.87727  28.04609 1.000 18.49143 ? 149 THR A HA   1 
ATOM   1929 H  HB   . THR A 1 126 ? 3.22899   -5.77295  29.25945 1.000 23.41771 ? 149 THR A HB   1 
ATOM   1930 H  HG1  . THR A 1 126 ? 2.29565   -5.19746  27.33247 1.000 21.39868 ? 149 THR A HG1  1 
ATOM   1931 H  HG21 . THR A 1 126 ? 5.14206   -6.72147  28.21815 1.000 19.38132 ? 149 THR A HG21 1 
ATOM   1932 H  HG22 . THR A 1 126 ? 4.57208   -7.62656  29.37937 1.000 19.38132 ? 149 THR A HG22 1 
ATOM   1933 H  HG23 . THR A 1 126 ? 4.27758   -7.99667  27.87312 1.000 19.38132 ? 149 THR A HG23 1 
ATOM   1934 N  N    . ALA A 1 127 ? 1.77766   -7.52150  31.22539 1.000 16.82843 ? 150 ALA A N    1 
ATOM   1935 C  CA   . ALA A 1 127 ? 1.89701   -8.27589  32.46439 1.000 18.99679 ? 150 ALA A CA   1 
ATOM   1936 C  C    . ALA A 1 127 ? 0.87552   -9.40088  32.50876 1.000 19.04600 ? 150 ALA A C    1 
ATOM   1937 O  O    . ALA A 1 127 ? 1.15406   -10.47561 33.04803 1.000 18.97131 ? 150 ALA A O    1 
ATOM   1938 C  CB   . ALA A 1 127 ? 1.73116   -7.34771  33.67171 1.000 20.86428 ? 150 ALA A CB   1 
ATOM   1939 H  H    . ALA A 1 127 ? 1.53707   -6.70203  31.32632 1.000 20.17404 ? 150 ALA A H    1 
ATOM   1940 H  HA   . ALA A 1 127 ? 2.78443   -8.66371  32.51897 1.000 22.77607 ? 150 ALA A HA   1 
ATOM   1941 H  HB1  . ALA A 1 127 ? 1.76430   -7.87702  34.48389 1.000 25.01706 ? 150 ALA A HB1  1 
ATOM   1942 H  HB2  . ALA A 1 127 ? 2.45076   -6.69727  33.67120 1.000 25.01706 ? 150 ALA A HB2  1 
ATOM   1943 H  HB3  . ALA A 1 127 ? 0.87586   -6.89480  33.60672 1.000 25.01706 ? 150 ALA A HB3  1 
ATOM   1944 N  N    . PHE A 1 128 ? -0.28466  -9.19454  31.90074 1.000 16.30676 ? 151 PHE A N    1 
ATOM   1945 C  CA   . PHE A 1 128 ? -1.29096  -10.24190 31.82890 1.000 19.72878 ? 151 PHE A CA   1 
ATOM   1946 C  C    . PHE A 1 128 ? -0.80244  -11.41073 30.98146 1.000 18.73321 ? 151 PHE A C    1 
ATOM   1947 O  O    . PHE A 1 128 ? -0.93086  -12.57231 31.37512 1.000 19.80893 ? 151 PHE A O    1 
ATOM   1948 C  CB   . PHE A 1 128 ? -2.58160  -9.66070  31.26764 1.000 17.46785 ? 151 PHE A CB   1 
ATOM   1949 C  CG   . PHE A 1 128 ? -3.60621  -10.70894 30.89826 1.000 15.51718 ? 151 PHE A CG   1 
ATOM   1950 C  CD1  . PHE A 1 128 ? -4.20732  -11.46818 31.88702 1.000 20.60645 ? 151 PHE A CD1  1 
ATOM   1951 C  CD2  . PHE A 1 128 ? -3.95998  -10.93187 29.58842 1.000 23.24263 ? 151 PHE A CD2  1 
ATOM   1952 C  CE1  . PHE A 1 128 ? -5.14466  -12.42892 31.55948 1.000 23.41432 ? 151 PHE A CE1  1 
ATOM   1953 C  CE2  . PHE A 1 128 ? -4.88291  -11.89990 29.26376 1.000 20.80021 ? 151 PHE A CE2  1 
ATOM   1954 C  CZ   . PHE A 1 128 ? -5.47899  -12.62700 30.28190 1.000 16.93766 ? 151 PHE A CZ   1 
ATOM   1955 H  H    . PHE A 1 128 ? -0.51428  -8.45747  31.52179 1.000 19.54803 ? 151 PHE A H    1 
ATOM   1956 H  HA   . PHE A 1 128 ? -1.47149  -10.58038 32.71982 1.000 23.65445 ? 151 PHE A HA   1 
ATOM   1957 H  HB2  . PHE A 1 128 ? -2.97885  -9.07948  31.93493 1.000 20.94134 ? 151 PHE A HB2  1 
ATOM   1958 H  HB3  . PHE A 1 128 ? -2.37397  -9.15356  30.46727 1.000 20.94134 ? 151 PHE A HB3  1 
ATOM   1959 H  HD1  . PHE A 1 128 ? -3.97875  -11.33075 32.77796 1.000 24.70766 ? 151 PHE A HD1  1 
ATOM   1960 H  HD2  . PHE A 1 128 ? -3.57123  -10.42277 28.91419 1.000 27.87107 ? 151 PHE A HD2  1 
ATOM   1961 H  HE1  . PHE A 1 128 ? -5.54268  -12.93757 32.22862 1.000 28.07710 ? 151 PHE A HE1  1 
ATOM   1962 H  HE2  . PHE A 1 128 ? -5.10306  -12.06351 28.37513 1.000 24.94017 ? 151 PHE A HE2  1 
ATOM   1963 H  HZ   . PHE A 1 128 ? -6.12313  -13.26403 30.07171 1.000 20.30512 ? 151 PHE A HZ   1 
ATOM   1964 N  N    . ALA A 1 129 ? -0.26130  -11.11757 29.79692 1.000 17.26786 ? 152 ALA A N    1 
ATOM   1965 C  CA   . ALA A 1 129 ? 0.39629   -12.15130 29.01325 1.000 19.16178 ? 152 ALA A CA   1 
ATOM   1966 C  C    . ALA A 1 129 ? 1.39481   -12.93425 29.85663 1.000 17.60003 ? 152 ALA A C    1 
ATOM   1967 O  O    . ALA A 1 129 ? 1.40186   -14.16881 29.84161 1.000 17.49166 ? 152 ALA A O    1 
ATOM   1968 C  CB   . ALA A 1 129 ? 1.08725   -11.50785 27.80397 1.000 17.14458 ? 152 ALA A CB   1 
ATOM   1969 H  H    . ALA A 1 129 ? -0.26357  -10.33811 29.43355 1.000 20.70136 ? 152 ALA A H    1 
ATOM   1970 H  HA   . ALA A 1 129 ? -0.26856  -12.77880 28.68903 1.000 22.97406 ? 152 ALA A HA   1 
ATOM   1971 H  HB1  . ALA A 1 129 ? 1.49112   -12.20462 27.26333 1.000 20.55341 ? 152 ALA A HB1  1 
ATOM   1972 H  HB2  . ALA A 1 129 ? 0.42667   -11.02560 27.28247 1.000 20.55341 ? 152 ALA A HB2  1 
ATOM   1973 H  HB3  . ALA A 1 129 ? 1.77066   -10.89598 28.11938 1.000 20.55341 ? 152 ALA A HB3  1 
ATOM   1974 N  N    . ARG A 1 130 ? 2.25884   -12.23293 30.60776 1.000 16.06868 ? 153 ARG A N    1 
ATOM   1975 C  CA   . ARG A 1 130 ? 3.26725   -12.93073 31.39521 1.000 16.91277 ? 153 ARG A CA   1 
ATOM   1976 C  C    . ARG A 1 130 ? 2.60121   -13.85620 32.40261 1.000 18.14737 ? 153 ARG A C    1 
ATOM   1977 O  O    . ARG A 1 130 ? 3.03267   -15.00605 32.59799 1.000 22.59428 ? 153 ARG A O    1 
ATOM   1978 C  CB   . ARG A 1 130 ? 4.15512   -11.92031 32.11654 1.000 17.58905 ? 153 ARG A CB   1 
ATOM   1979 C  CG   . ARG A 1 130 ? 4.97840   -11.02259 31.19909 1.000 19.64522 ? 153 ARG A CG   1 
ATOM   1980 C  CD   . ARG A 1 130 ? 6.07788   -11.79914 30.49619 1.000 21.90008 ? 153 ARG A CD   1 
ATOM   1981 N  NE   . ARG A 1 130 ? 6.80181   -10.90638 29.59626 1.000 22.08798 ? 153 ARG A NE   1 
ATOM   1982 C  CZ   . ARG A 1 130 ? 6.34847   -10.54172 28.40710 1.000 21.92594 ? 153 ARG A CZ   1 
ATOM   1983 N  NH1  . ARG A 1 130 ? 5.29462   -11.13990 27.84948 1.000 19.39394 ? 153 ARG A NH1  1 
ATOM   1984 N  NH2  . ARG A 1 130 ? 6.96183   -9.55036  27.75852 1.000 22.42969 ? 153 ARG A NH2  1 
ATOM   1985 H  H    . ARG A 1 130 ? 2.27653   -11.37557 30.67272 1.000 19.26233 ? 153 ARG A H    1 
ATOM   1986 H  HA   . ARG A 1 130 ? 3.82841   -13.45828 30.80556 1.000 20.27525 ? 153 ARG A HA   1 
ATOM   1987 H  HB2  . ARG A 1 130 ? 3.59092   -11.34572 32.65730 1.000 21.08678 ? 153 ARG A HB2  1 
ATOM   1988 H  HB3  . ARG A 1 130 ? 4.77521   -12.40505 32.68347 1.000 21.08678 ? 153 ARG A HB3  1 
ATOM   1989 H  HG2  . ARG A 1 130 ? 4.39904   -10.63639 30.52375 1.000 23.55418 ? 153 ARG A HG2  1 
ATOM   1990 H  HG3  . ARG A 1 130 ? 5.39073   -10.31896 31.72425 1.000 23.55418 ? 153 ARG A HG3  1 
ATOM   1991 H  HD2  . ARG A 1 130 ? 6.69857   -12.15629 31.15048 1.000 26.26001 ? 153 ARG A HD2  1 
ATOM   1992 H  HD3  . ARG A 1 130 ? 5.69066   -12.52150 29.97738 1.000 26.26001 ? 153 ARG A HD3  1 
ATOM   1993 H  HE   . ARG A 1 130 ? 7.56383   -10.60087 29.85238 1.000 26.48550 ? 153 ARG A HE   1 
ATOM   1994 H  HH11 . ARG A 1 130 ? 4.89345   -11.77802 28.26357 1.000 23.25264 ? 153 ARG A HH11 1 
ATOM   1995 H  HH12 . ARG A 1 130 ? 5.01637   -10.88744 27.07589 1.000 23.25264 ? 153 ARG A HH12 1 
ATOM   1996 H  HH21 . ARG A 1 130 ? 7.64037   -9.15916  28.11370 1.000 26.89555 ? 153 ARG A HH21 1 
ATOM   1997 H  HH22 . ARG A 1 130 ? 6.67871   -9.30247  26.98522 1.000 26.89555 ? 153 ARG A HH22 1 
ATOM   1998 N  N    . GLN A 1 131 ? 1.52082   -13.37333 33.02862 1.000 17.97366 ? 154 GLN A N    1 
ATOM   1999 C  CA   . GLN A 1 131 ? 0.78653   -14.17832 34.00415 1.000 22.35926 ? 154 GLN A CA   1 
ATOM   2000 C  C    . GLN A 1 131 ? 0.28548   -15.48221 33.40312 1.000 20.83344 ? 154 GLN A C    1 
ATOM   2001 O  O    . GLN A 1 131 ? 0.19150   -16.48468 34.11326 1.000 22.22660 ? 154 GLN A O    1 
ATOM   2002 C  CB   . GLN A 1 131 ? -0.37132  -13.35098 34.59109 1.000 25.02374 ? 154 GLN A CB   1 
ATOM   2003 C  CG   . GLN A 1 131 ? -1.05057  -13.95255 35.79874 1.000 36.98915 ? 154 GLN A CG   1 
ATOM   2004 C  CD   . GLN A 1 131 ? -2.16475  -13.07173 36.37515 1.000 46.60648 ? 154 GLN A CD   1 
ATOM   2005 O  OE1  . GLN A 1 131 ? -2.49627  -11.99907 35.83985 1.000 44.66724 ? 154 GLN A OE1  1 
ATOM   2006 N  NE2  . GLN A 1 131 ? -2.74344  -13.52797 37.48525 1.000 54.56023 ? 154 GLN A NE2  1 
ATOM   2007 H  H    . GLN A 1 131 ? 1.19559   -12.58673 32.90581 1.000 21.54831 ? 154 GLN A H    1 
ATOM   2008 H  HA   . GLN A 1 131 ? 1.38060   -14.41442 34.73370 1.000 26.81103 ? 154 GLN A HA   1 
ATOM   2009 H  HB2  . GLN A 1 131 ? -0.02409  -12.48493 34.85622 1.000 30.00841 ? 154 GLN A HB2  1 
ATOM   2010 H  HB3  . GLN A 1 131 ? -1.04720  -13.24124 33.90403 1.000 30.00841 ? 154 GLN A HB3  1 
ATOM   2011 H  HG2  . GLN A 1 131 ? -1.44469  -14.80200 35.54574 1.000 44.36690 ? 154 GLN A HG2  1 
ATOM   2012 H  HG3  . GLN A 1 131 ? -0.38908  -14.08803 36.49514 1.000 44.36690 ? 154 GLN A HG3  1 
ATOM   2013 H  HE21 . GLN A 1 131 ? -2.48489  -14.27206 37.83034 1.000 65.45219 ? 154 GLN A HE21 1 
ATOM   2014 H  HE22 . GLN A 1 131 ? -3.37550  -13.07836 37.85667 1.000 65.45219 ? 154 GLN A HE22 1 
ATOM   2015 N  N    . LEU A 1 132 ? -0.02146  -15.49183 32.10525 1.000 20.61374 ? 155 LEU A N    1 
ATOM   2016 C  CA   . LEU A 1 132 ? -0.47613  -16.68135 31.39378 1.000 22.27873 ? 155 LEU A CA   1 
ATOM   2017 C  C    . LEU A 1 132 ? 0.66159   -17.58275 30.93479 1.000 27.94516 ? 155 LEU A C    1 
ATOM   2018 O  O    . LEU A 1 132 ? 0.40458   -18.60399 30.28447 1.000 25.77854 ? 155 LEU A O    1 
ATOM   2019 C  CB   . LEU A 1 132 ? -1.26882  -16.29435 30.15030 1.000 21.52623 ? 155 LEU A CB   1 
ATOM   2020 C  CG   . LEU A 1 132 ? -2.52988  -15.45747 30.28593 1.000 27.53199 ? 155 LEU A CG   1 
ATOM   2021 C  CD1  . LEU A 1 132 ? -3.16004  -15.29866 28.91698 1.000 25.27208 ? 155 LEU A CD1  1 
ATOM   2022 C  CD2  . LEU A 1 132 ? -3.47761  -16.10084 31.28354 1.000 33.31974 ? 155 LEU A CD2  1 
ATOM   2023 H  H    . LEU A 1 132 ? 0.02781   -14.79771 31.59991 1.000 24.71641 ? 155 LEU A H    1 
ATOM   2024 H  HA   . LEU A 1 132 ? -1.05004  -17.17186 32.00282 1.000 26.71440 ? 155 LEU A HA   1 
ATOM   2025 H  HB2  . LEU A 1 132 ? -0.67172  -15.79181 29.57425 1.000 25.81139 ? 155 LEU A HB2  1 
ATOM   2026 H  HB3  . LEU A 1 132 ? -1.53670  -17.11770 29.71300 1.000 25.81139 ? 155 LEU A HB3  1 
ATOM   2027 H  HG   . LEU A 1 132 ? -2.32617  -14.57239 30.62657 1.000 33.01831 ? 155 LEU A HG   1 
ATOM   2028 H  HD11 . LEU A 1 132 ? -3.95455  -14.74798 28.99701 1.000 30.30642 ? 155 LEU A HD11 1 
ATOM   2029 H  HD12 . LEU A 1 132 ? -2.52168  -14.87396 28.32282 1.000 30.30642 ? 155 LEU A HD12 1 
ATOM   2030 H  HD13 . LEU A 1 132 ? -3.39786  -16.17477 28.57524 1.000 30.30642 ? 155 LEU A HD13 1 
ATOM   2031 H  HD21 . LEU A 1 132 ? -4.31288  -15.60768 31.28893 1.000 39.96360 ? 155 LEU A HD21 1 
ATOM   2032 H  HD22 . LEU A 1 132 ? -3.63800  -17.02021 31.01910 1.000 39.96360 ? 155 LEU A HD22 1 
ATOM   2033 H  HD23 . LEU A 1 132 ? -3.07306  -16.07590 32.16480 1.000 39.96360 ? 155 LEU A HD23 1 
ATOM   2034 N  N    . GLY A 1 133 ? 1.90914   -17.19231 31.16220 1.000 21.13361 ? 156 GLY A N    1 
ATOM   2035 C  CA   . GLY A 1 133 ? 3.02075   -17.94882 30.65321 1.000 20.57922 ? 156 GLY A CA   1 
ATOM   2036 C  C    . GLY A 1 133 ? 3.52209   -17.53815 29.29073 1.000 18.05565 ? 156 GLY A C    1 
ATOM   2037 O  O    . GLY A 1 133 ? 4.32351   -18.27460 28.70216 1.000 24.96462 ? 156 GLY A O    1 
ATOM   2038 H  H    . GLY A 1 133 ? 2.12834   -16.49134 31.60962 1.000 25.34025 ? 156 GLY A H    1 
ATOM   2039 H  HA2  . GLY A 1 133 ? 3.76057   -17.86380 31.27476 1.000 24.67499 ? 156 GLY A HA2  1 
ATOM   2040 H  HA3  . GLY A 1 133 ? 2.75895   -18.88127 30.59952 1.000 24.67499 ? 156 GLY A HA3  1 
ATOM   2041 N  N    . ASP A 1 134 ? 3.10252   -16.38519 28.77003 1.000 17.75873 ? 157 ASP A N    1 
ATOM   2042 C  CA   . ASP A 1 134 ? 3.59926   -15.87848 27.49645 1.000 16.87861 ? 157 ASP A CA   1 
ATOM   2043 C  C    . ASP A 1 134 ? 4.68575   -14.84644 27.81237 1.000 20.93422 ? 157 ASP A C    1 
ATOM   2044 O  O    . ASP A 1 134 ? 4.38888   -13.75261 28.28293 1.000 16.83548 ? 157 ASP A O    1 
ATOM   2045 C  CB   . ASP A 1 134 ? 2.44450   -15.30619 26.69061 1.000 14.39713 ? 157 ASP A CB   1 
ATOM   2046 C  CG   . ASP A 1 134 ? 2.84937   -14.85863 25.29941 1.000 15.18182 ? 157 ASP A CG   1 
ATOM   2047 O  OD1  . ASP A 1 134 ? 4.02729   -14.48655 25.07103 1.000 14.51901 ? 157 ASP A OD1  1 
ATOM   2048 O  OD2  . ASP A 1 134 ? 1.95999   -14.84788 24.45460 1.000 15.27800 ? 157 ASP A OD2  1 
ATOM   2049 H  H    . ASP A 1 134 ? 2.52161   -15.87284 29.14370 1.000 21.29040 ? 157 ASP A H    1 
ATOM   2050 H  HA   . ASP A 1 134 ? 4.00676   -16.57838 26.96261 1.000 20.23425 ? 157 ASP A HA   1 
ATOM   2051 H  HB2  . ASP A 1 134 ? 1.75914   -15.98622 26.59707 1.000 17.25648 ? 157 ASP A HB2  1 
ATOM   2052 H  HB3  . ASP A 1 134 ? 2.08594   -14.53599 27.15872 1.000 17.25648 ? 157 ASP A HB3  1 
ATOM   2053 N  N    . GLU A 1 135 ? 5.94619   -15.20323 27.57864 1.000 19.69987 ? 158 GLU A N    1 
ATOM   2054 C  CA   . GLU A 1 135 ? 7.07324   -14.32326 27.87400 1.000 17.28612 ? 158 GLU A CA   1 
ATOM   2055 C  C    . GLU A 1 135 ? 7.58948   -13.64552 26.61071 1.000 23.71465 ? 158 GLU A C    1 
ATOM   2056 O  O    . GLU A 1 135 ? 8.63221   -12.99491 26.64886 1.000 20.00199 ? 158 GLU A O    1 
ATOM   2057 C  CB   . GLU A 1 135 ? 8.15929   -15.11673 28.63965 1.000 23.18037 ? 158 GLU A CB   1 
ATOM   2058 C  CG   . GLU A 1 135 ? 7.54326   -15.63363 30.00928 1.000 26.46784 ? 158 GLU A CG   1 
ATOM   2059 C  CD   . GLU A 1 135 ? 8.51571   -16.09957 31.11006 1.000 44.65298 ? 158 GLU A CD   1 
ATOM   2060 O  OE1  . GLU A 1 135 ? 9.72443   -16.22656 30.85025 1.000 28.44279 ? 158 GLU A OE1  1 
ATOM   2061 O  OE2  . GLU A 1 135 ? 8.05187   -16.36178 32.26137 1.000 31.06830 ? 158 GLU A OE2  1 
ATOM   2062 H  H    . GLU A 1 135 ? 6.17696   -15.96129 27.24444 1.000 23.61977 ? 158 GLU A H    1 
ATOM   2063 H  HA   . GLU A 1 135 ? 6.81202   -13.60631 28.47288 1.000 20.72326 ? 158 GLU A HA   1 
ATOM   2064 H  HB2  . GLU A 1 135 ? 8.44532   -15.87925 28.11273 1.000 27.79636 ? 158 GLU A HB2  1 
ATOM   2065 H  HB3  . GLU A 1 135 ? 8.91705   -14.54177 28.82968 1.000 27.79636 ? 158 GLU A HB3  1 
ATOM   2066 H  HG2  . GLU A 1 135 ? 7.01987   -14.91087 30.38949 1.000 31.74133 ? 158 GLU A HG2  1 
ATOM   2067 H  HG3  . GLU A 1 135 ? 6.96900   -16.38920 29.80868 1.000 31.74133 ? 158 GLU A HG3  1 
ATOM   2068 N  N    . THR A 1 136 ? 6.81268   -13.69827 25.52524 1.000 15.16098 ? 159 THR A N    1 
ATOM   2069 C  CA   . THR A 1 136 ? 7.21028   -13.15120 24.23385 1.000 16.32017 ? 159 THR A CA   1 
ATOM   2070 C  C    . THR A 1 136 ? 6.40551   -11.92119 23.85841 1.000 19.19090 ? 159 THR A C    1 
ATOM   2071 O  O    . THR A 1 136 ? 6.96877   -10.92981 23.41629 1.000 17.34923 ? 159 THR A O    1 
ATOM   2072 C  CB   . THR A 1 136 ? 7.05513   -14.21845 23.13903 1.000 21.10694 ? 159 THR A CB   1 
ATOM   2073 O  OG1  . THR A 1 136 ? 7.75453   -15.40253 23.52830 1.000 19.95034 ? 159 THR A OG1  1 
ATOM   2074 C  CG2  . THR A 1 136 ? 7.63405   -13.70585 21.78256 1.000 20.40036 ? 159 THR A CG2  1 
ATOM   2075 H  H    . THR A 1 136 ? 6.03086   -14.05641 25.51608 1.000 18.17309 ? 159 THR A H    1 
ATOM   2076 H  HA   . THR A 1 136 ? 8.14651   -12.90091 24.27528 1.000 19.56412 ? 159 THR A HA   1 
ATOM   2077 H  HB   . THR A 1 136 ? 6.11414   -14.41807 23.01417 1.000 25.30825 ? 159 THR A HB   1 
ATOM   2078 H  HG1  . THR A 1 136 ? 8.57539   -15.24020 23.60205 1.000 23.92033 ? 159 THR A HG1  1 
ATOM   2079 H  HG21 . THR A 1 136 ? 7.66888   -14.43251 21.14095 1.000 24.46035 ? 159 THR A HG21 1 
ATOM   2080 H  HG22 . THR A 1 136 ? 7.07200   -12.99934 21.42780 1.000 24.46035 ? 159 THR A HG22 1 
ATOM   2081 H  HG23 . THR A 1 136 ? 8.53027   -13.35896 21.91426 1.000 24.46035 ? 159 THR A HG23 1 
ATOM   2082 N  N    . PHE A 1 137 ? 5.08588   -11.99905 24.00928 1.000 15.41187 ? 160 PHE A N    1 
ATOM   2083 C  CA   . PHE A 1 137 ? 4.18365   -10.89986 23.74074 1.000 15.46570 ? 160 PHE A CA   1 
ATOM   2084 C  C    . PHE A 1 137 ? 4.65627   -9.61342  24.40606 1.000 15.22163 ? 160 PHE A C    1 
ATOM   2085 O  O    . PHE A 1 137 ? 4.94715   -9.58525  25.61382 1.000 15.59093 ? 160 PHE A O    1 
ATOM   2086 C  CB   . PHE A 1 137 ? 2.79664   -11.29734 24.25282 1.000 13.22687 ? 160 PHE A CB   1 
ATOM   2087 C  CG   . PHE A 1 137 ? 1.77514   -10.20917 24.16498 1.000 16.83023 ? 160 PHE A CG   1 
ATOM   2088 C  CD1  . PHE A 1 137 ? 1.74474   -9.19559  25.12349 1.000 19.41932 ? 160 PHE A CD1  1 
ATOM   2089 C  CD2  . PHE A 1 137 ? 0.81827   -10.21677 23.15660 1.000 17.14959 ? 160 PHE A CD2  1 
ATOM   2090 C  CE1  . PHE A 1 137 ? 0.79171   -8.18688  25.07031 1.000 14.91806 ? 160 PHE A CE1  1 
ATOM   2091 C  CE2  . PHE A 1 137 ? -0.13941  -9.24357  23.08174 1.000 17.30312 ? 160 PHE A CE2  1 
ATOM   2092 C  CZ   . PHE A 1 137 ? -0.16212  -8.20789  24.01553 1.000 18.14503 ? 160 PHE A CZ   1 
ATOM   2093 H  H    . PHE A 1 137 ? 4.67787   -12.70734 24.27661 1.000 18.47416 ? 160 PHE A H    1 
ATOM   2094 H  HA   . PHE A 1 137 ? 4.14285   -10.72230 22.78801 1.000 18.53876 ? 160 PHE A HA   1 
ATOM   2095 H  HB2  . PHE A 1 137 ? 2.47471   -12.04601 23.72674 1.000 15.85216 ? 160 PHE A HB2  1 
ATOM   2096 H  HB3  . PHE A 1 137 ? 2.87236   -11.55503 25.18490 1.000 15.85216 ? 160 PHE A HB3  1 
ATOM   2097 H  HD1  . PHE A 1 137 ? 2.37300   -9.19555  25.80920 1.000 23.28310 ? 160 PHE A HD1  1 
ATOM   2098 H  HD2  . PHE A 1 137 ? 0.82965   -10.89600 22.52146 1.000 20.55943 ? 160 PHE A HD2  1 
ATOM   2099 H  HE1  . PHE A 1 137 ? 0.77751   -7.51237  25.71042 1.000 17.88160 ? 160 PHE A HE1  1 
ATOM   2100 H  HE2  . PHE A 1 137 ? -0.77766  -9.27239  22.40594 1.000 20.74366 ? 160 PHE A HE2  1 
ATOM   2101 H  HZ   . PHE A 1 137 ? -0.79881  -7.53330  23.94872 1.000 21.75396 ? 160 PHE A HZ   1 
ATOM   2102 N  N    . ARG A 1 138 ? 4.71103   -8.53392  23.62608 1.000 15.31355 ? 161 ARG A N    1 
ATOM   2103 C  CA   . ARG A 1 138 ? 4.85797   -7.21036  24.22756 1.000 16.57877 ? 161 ARG A CA   1 
ATOM   2104 C  C    . ARG A 1 138 ? 3.92836   -6.20495  23.55448 1.000 19.08258 ? 161 ARG A C    1 
ATOM   2105 O  O    . ARG A 1 138 ? 3.90087   -6.07662  22.32738 1.000 19.48295 ? 161 ARG A O    1 
ATOM   2106 C  CB   . ARG A 1 138 ? 6.31242   -6.69667  24.19688 1.000 18.29649 ? 161 ARG A CB   1 
ATOM   2107 C  CG   . ARG A 1 138 ? 6.94514   -6.68368  22.84876 1.000 16.58658 ? 161 ARG A CG   1 
ATOM   2108 C  CD   . ARG A 1 138 ? 8.42303   -6.40855  22.97974 1.000 16.90994 ? 161 ARG A CD   1 
ATOM   2109 N  NE   . ARG A 1 138 ? 8.60557   -4.98773  23.23742 1.000 17.03229 ? 161 ARG A NE   1 
ATOM   2110 C  CZ   . ARG A 1 138 ? 9.77310   -4.37313  23.36390 1.000 16.40420 ? 161 ARG A CZ   1 
ATOM   2111 N  NH1  . ARG A 1 138 ? 10.91687  -5.04209  23.34923 1.000 19.52069 ? 161 ARG A NH1  1 
ATOM   2112 N  NH2  . ARG A 1 138 ? 9.78833   -3.05256  23.48399 1.000 22.66329 ? 161 ARG A NH2  1 
ATOM   2113 H  H    . ARG A 1 138 ? 4.66623   -8.54313  22.76730 1.000 18.35618 ? 161 ARG A H    1 
ATOM   2114 H  HA   . ARG A 1 138 ? 4.58961   -7.28428  25.15676 1.000 19.87445 ? 161 ARG A HA   1 
ATOM   2115 H  HB2  . ARG A 1 138 ? 6.32406   -5.78675  24.53274 1.000 21.93571 ? 161 ARG A HB2  1 
ATOM   2116 H  HB3  . ARG A 1 138 ? 6.85191   -7.26738  24.76621 1.000 21.93571 ? 161 ARG A HB3  1 
ATOM   2117 H  HG2  . ARG A 1 138 ? 6.82514   -7.54652  22.42214 1.000 19.88381 ? 161 ARG A HG2  1 
ATOM   2118 H  HG3  . ARG A 1 138 ? 6.54506   -5.98658  22.30572 1.000 19.88381 ? 161 ARG A HG3  1 
ATOM   2119 H  HD2  . ARG A 1 138 ? 8.79156   -6.91574  23.71991 1.000 20.27185 ? 161 ARG A HD2  1 
ATOM   2120 H  HD3  . ARG A 1 138 ? 8.87943   -6.64353  22.15671 1.000 20.27185 ? 161 ARG A HD3  1 
ATOM   2121 H  HE   . ARG A 1 138 ? 7.89672   -4.50683  23.31400 1.000 20.41866 ? 161 ARG A HE   1 
ATOM   2122 H  HH11 . ARG A 1 138 ? 10.91383  -5.89700  23.25588 1.000 23.40475 ? 161 ARG A HH11 1 
ATOM   2123 H  HH12 . ARG A 1 138 ? 11.66221  -4.62134  23.43307 1.000 23.40475 ? 161 ARG A HH12 1 
ATOM   2124 H  HH21 . ARG A 1 138 ? 9.04990   -2.61177  23.47885 1.000 27.17587 ? 161 ARG A HH21 1 
ATOM   2125 H  HH22 . ARG A 1 138 ? 10.53664  -2.63694  23.56701 1.000 27.17587 ? 161 ARG A HH22 1 
ATOM   2126 N  N    . LEU A 1 139 ? 3.13172   -5.52250  24.37384 1.000 17.80750 ? 162 LEU A N    1 
ATOM   2127 C  CA   . LEU A 1 139 ? 2.31453   -4.40194  23.94375 1.000 15.97783 ? 162 LEU A CA   1 
ATOM   2128 C  C    . LEU A 1 139 ? 2.93857   -3.16687  24.56709 1.000 17.94851 ? 162 LEU A C    1 
ATOM   2129 O  O    . LEU A 1 139 ? 3.09961   -3.09918  25.80033 1.000 16.21134 ? 162 LEU A O    1 
ATOM   2130 C  CB   . LEU A 1 139 ? 0.84735   -4.56683  24.34612 1.000 15.95741 ? 162 LEU A CB   1 
ATOM   2131 C  CG   . LEU A 1 139 ? -0.06549  -3.54147  23.63438 1.000 16.20316 ? 162 LEU A CG   1 
ATOM   2132 C  CD1  . LEU A 1 139 ? -0.17359  -3.81670  22.11635 1.000 16.23929 ? 162 LEU A CD1  1 
ATOM   2133 C  CD2  . LEU A 1 139 ? -1.44024  -3.53812  24.29049 1.000 18.79938 ? 162 LEU A CD2  1 
ATOM   2134 H  H    . LEU A 1 139 ? 3.04821   -5.69967  25.21124 1.000 21.34892 ? 162 LEU A H    1 
ATOM   2135 H  HA   . LEU A 1 139 ? 2.31400   -4.32168  22.97708 1.000 19.15331 ? 162 LEU A HA   1 
ATOM   2136 H  HB2  . LEU A 1 139 ? 0.54962   -5.45810  24.10552 1.000 19.12882 ? 162 LEU A HB2  1 
ATOM   2137 H  HB3  . LEU A 1 139 ? 0.76335   -4.43618  25.30361 1.000 19.12882 ? 162 LEU A HB3  1 
ATOM   2138 H  HG   . LEU A 1 139 ? 0.32698   -2.65895  23.72401 1.000 19.42372 ? 162 LEU A HG   1 
ATOM   2139 H  HD11 . LEU A 1 139 ? -0.88744  -3.27366  21.74699 1.000 19.46706 ? 162 LEU A HD11 1 
ATOM   2140 H  HD12 . LEU A 1 139 ? 0.66876   -3.58808  21.69317 1.000 19.46706 ? 162 LEU A HD12 1 
ATOM   2141 H  HD13 . LEU A 1 139 ? -0.36832  -4.75697  21.97896 1.000 19.46706 ? 162 LEU A HD13 1 
ATOM   2142 H  HD21 . LEU A 1 139 ? -1.99795  -2.87679  23.85174 1.000 22.53918 ? 162 LEU A HD21 1 
ATOM   2143 H  HD22 . LEU A 1 139 ? -1.83642  -4.41870  24.19807 1.000 22.53918 ? 162 LEU A HD22 1 
ATOM   2144 H  HD23 . LEU A 1 139 ? -1.34138  -3.31681  25.22971 1.000 22.53918 ? 162 LEU A HD23 1 
ATOM   2145 N  N    . ASP A 1 140 ? 3.38462   -2.24964  23.70885 1.000 16.56795 ? 163 ASP A N    1 
ATOM   2146 C  CA   . ASP A 1 140 ? 4.20914   -1.10420  24.06623 1.000 15.75243 ? 163 ASP A CA   1 
ATOM   2147 C  C    . ASP A 1 140 ? 3.46396   0.20694   23.98769 1.000 16.08306 ? 163 ASP A C    1 
ATOM   2148 O  O    . ASP A 1 140 ? 3.71333   1.11423   24.78955 1.000 18.87948 ? 163 ASP A O    1 
ATOM   2149 C  CB   . ASP A 1 140 ? 5.42152   -0.93238  23.13884 1.000 19.15799 ? 163 ASP A CB   1 
ATOM   2150 C  CG   . ASP A 1 140 ? 6.50936   -1.96807  23.34199 1.000 26.93350 ? 163 ASP A CG   1 
ATOM   2151 O  OD1  . ASP A 1 140 ? 6.28127   -3.14011  22.96939 1.000 16.07093 ? 163 ASP A OD1  1 
ATOM   2152 O  OD2  . ASP A 1 140 ? 7.61652   -1.58273  23.78856 1.000 30.14251 ? 163 ASP A OD2  1 
ATOM   2153 H  H    . ASP A 1 140 ? 3.21099   -2.27388  22.86691 1.000 19.86146 ? 163 ASP A H    1 
ATOM   2154 H  HA   . ASP A 1 140 ? 4.52860   -1.27909  24.96526 1.000 18.88283 ? 163 ASP A HA   1 
ATOM   2155 H  HB2  . ASP A 1 140 ? 5.12090   -0.99831  22.21896 1.000 22.96950 ? 163 ASP A HB2  1 
ATOM   2156 H  HB3  . ASP A 1 140 ? 5.81329   -0.05941  23.29808 1.000 22.96950 ? 163 ASP A HB3  1 
ATOM   2157 N  N    . ARG A 1 141 ? 2.58307   0.32568   23.00186 1.000 17.48825 ? 164 ARG A N    1 
ATOM   2158 C  CA   . ARG A 1 141 ? 1.94737   1.57740   22.64448 1.000 14.86907 ? 164 ARG A CA   1 
ATOM   2159 C  C    . ARG A 1 141 ? 0.43769   1.38243   22.55603 1.000 13.89650 ? 164 ARG A C    1 
ATOM   2160 O  O    . ARG A 1 141 ? -0.07708  0.25889   22.55558 1.000 16.66565 ? 164 ARG A O    1 
ATOM   2161 C  CB   . ARG A 1 141 ? 2.48539   2.12364   21.30842 1.000 15.93391 ? 164 ARG A CB   1 
ATOM   2162 C  CG   . ARG A 1 141 ? 3.90824   2.65758   21.41638 1.000 17.72834 ? 164 ARG A CG   1 
ATOM   2163 C  CD   . ARG A 1 141 ? 4.54299   2.94919   20.03205 1.000 21.54292 ? 164 ARG A CD   1 
ATOM   2164 N  NE   . ARG A 1 141 ? 4.66642   1.72214   19.26534 1.000 20.90625 ? 164 ARG A NE   1 
ATOM   2165 C  CZ   . ARG A 1 141 ? 5.06104   1.64981   17.99689 1.000 17.89593 ? 164 ARG A CZ   1 
ATOM   2166 N  NH1  . ARG A 1 141 ? 5.42933   2.73343   17.31542 1.000 16.67455 ? 164 ARG A NH1  1 
ATOM   2167 N  NH2  . ARG A 1 141 ? 5.06264   0.47574   17.39250 1.000 17.33965 ? 164 ARG A NH2  1 
ATOM   2168 H  H    . ARG A 1 141 ? 2.33074   -0.33257  22.50928 1.000 20.96582 ? 164 ARG A H    1 
ATOM   2169 H  HA   . ARG A 1 141 ? 2.12958   2.22893   23.33961 1.000 17.82280 ? 164 ARG A HA   1 
ATOM   2170 H  HB2  . ARG A 1 141 ? 2.48211   1.40963   20.65185 1.000 19.10061 ? 164 ARG A HB2  1 
ATOM   2171 H  HB3  . ARG A 1 141 ? 1.91443   2.84959   21.01196 1.000 19.10061 ? 164 ARG A HB3  1 
ATOM   2172 H  HG2  . ARG A 1 141 ? 3.89870   3.48509   21.92237 1.000 21.25393 ? 164 ARG A HG2  1 
ATOM   2173 H  HG3  . ARG A 1 141 ? 4.46037   1.99954   21.86698 1.000 21.25393 ? 164 ARG A HG3  1 
ATOM   2174 H  HD2  . ARG A 1 141 ? 3.98045   3.56720   19.53960 1.000 25.83142 ? 164 ARG A HD2  1 
ATOM   2175 H  HD3  . ARG A 1 141 ? 5.42711   3.32951   20.15287 1.000 25.83142 ? 164 ARG A HD3  1 
ATOM   2176 H  HE   . ARG A 1 141 ? 4.46911   0.98504   19.66200 1.000 25.06742 ? 164 ARG A HE   1 
ATOM   2177 H  HH11 . ARG A 1 141 ? 5.41575   3.50514   17.69471 1.000 19.98938 ? 164 ARG A HH11 1 
ATOM   2178 H  HH12 . ARG A 1 141 ? 5.68068   2.66133   16.49613 1.000 19.98938 ? 164 ARG A HH12 1 
ATOM   2179 H  HH21 . ARG A 1 141 ? 4.81103   -0.22760  17.81865 1.000 20.78749 ? 164 ARG A HH21 1 
ATOM   2180 H  HH22 . ARG A 1 141 ? 5.31530   0.41445   16.57274 1.000 20.78749 ? 164 ARG A HH22 1 
ATOM   2181 N  N    . THR A 1 142 ? -0.24724  2.52250   22.51440 1.000 16.50573 ? 165 THR A N    1 
ATOM   2182 C  CA   . THR A 1 142 ? -1.67301  2.60092   22.29427 1.000 16.17243 ? 165 THR A CA   1 
ATOM   2183 C  C    . THR A 1 142 ? -1.99009  2.73888   20.80915 1.000 15.58257 ? 165 THR A C    1 
ATOM   2184 O  O    . THR A 1 142 ? -1.10027  2.78695   19.95584 1.000 17.12132 ? 165 THR A O    1 
ATOM   2185 C  CB   . THR A 1 142 ? -2.25044  3.79351   23.04047 1.000 15.70870 ? 165 THR A CB   1 
ATOM   2186 O  OG1  . THR A 1 142 ? -1.63227  4.98934   22.56504 1.000 15.74719 ? 165 THR A OG1  1 
ATOM   2187 C  CG2  . THR A 1 142 ? -2.05169  3.68797   24.54826 1.000 16.51524 ? 165 THR A CG2  1 
ATOM   2188 H  H    . THR A 1 142 ? 0.11490   3.29583   22.61646 1.000 19.78679 ? 165 THR A H    1 
ATOM   2189 H  HA   . THR A 1 142 ? -2.06683  1.77860   22.62533 1.000 19.38683 ? 165 THR A HA   1 
ATOM   2190 H  HB   . THR A 1 142 ? -3.20707  3.82105   22.88235 1.000 18.83036 ? 165 THR A HB   1 
ATOM   2191 H  HG1  . THR A 1 142 ? -1.87028  5.14080   21.77383 1.000 18.87654 ? 165 THR A HG1  1 
ATOM   2192 H  HG21 . THR A 1 142 ? -2.48650  4.43225   24.99311 1.000 19.79820 ? 165 THR A HG21 1 
ATOM   2193 H  HG22 . THR A 1 142 ? -2.43358  2.85872   24.87599 1.000 19.79820 ? 165 THR A HG22 1 
ATOM   2194 H  HG23 . THR A 1 142 ? -1.10523  3.70403   24.76007 1.000 19.79820 ? 165 THR A HG23 1 
ATOM   2195 N  N    . GLU A 1 143 ? -3.30037  2.77008   20.48639 1.000 16.42205 ? 166 GLU A N    1 
ATOM   2196 C  CA   . GLU A 1 143 ? -3.70112  3.07487   19.11224 1.000 17.53344 ? 166 GLU A CA   1 
ATOM   2197 C  C    . GLU A 1 143 ? -3.63049  4.58435   18.87224 1.000 16.23022 ? 166 GLU A C    1 
ATOM   2198 O  O    . GLU A 1 143 ? -3.99518  5.36260   19.74985 1.000 17.00949 ? 166 GLU A O    1 
ATOM   2199 C  CB   . GLU A 1 143 ? -5.13365  2.58697   18.85046 1.000 16.25085 ? 166 GLU A CB   1 
ATOM   2200 C  CG   . GLU A 1 143 ? -5.36280  1.08927   19.07832 1.000 18.24872 ? 166 GLU A CG   1 
ATOM   2201 C  CD   . GLU A 1 143 ? -4.88222  0.22715   17.94050 1.000 17.50932 ? 166 GLU A CD   1 
ATOM   2202 O  OE1  . GLU A 1 143 ? -4.35860  0.80803   16.96959 1.000 15.50833 ? 166 GLU A OE1  1 
ATOM   2203 O  OE2  . GLU A 1 143 ? -5.04801  -1.02277  17.98469 1.000 15.26006 ? 166 GLU A OE2  1 
ATOM   2204 H  H    . GLU A 1 143 ? -3.94893  2.62236   21.03150 1.000 19.68639 ? 166 GLU A H    1 
ATOM   2205 H  HA   . GLU A 1 143 ? -3.10387  2.62862   18.49171 1.000 21.02004 ? 166 GLU A HA   1 
ATOM   2206 H  HB2  . GLU A 1 143 ? -5.73366  3.06592   19.44334 1.000 19.48093 ? 166 GLU A HB2  1 
ATOM   2207 H  HB3  . GLU A 1 143 ? -5.35827  2.77768   17.92630 1.000 19.48093 ? 166 GLU A HB3  1 
ATOM   2208 H  HG2  . GLU A 1 143 ? -4.88590  0.81771   19.87814 1.000 21.87838 ? 166 GLU A HG2  1 
ATOM   2209 H  HG3  . GLU A 1 143 ? -6.31341  0.93129   19.18914 1.000 21.87838 ? 166 GLU A HG3  1 
ATOM   2210 N  N    . PRO A 1 144 ? -3.23287  5.02602   17.66698 1.000 19.39223 ? 167 PRO A N    1 
ATOM   2211 C  CA   . PRO A 1 144 ? -2.94612  4.18511   16.50927 1.000 18.88006 ? 167 PRO A CA   1 
ATOM   2212 C  C    . PRO A 1 144 ? -1.46753  3.86433   16.30804 1.000 21.48822 ? 167 PRO A C    1 
ATOM   2213 O  O    . PRO A 1 144 ? -1.14433  3.14126   15.37658 1.000 19.44486 ? 167 PRO A O    1 
ATOM   2214 C  CB   . PRO A 1 144 ? -3.48820  5.03912   15.35453 1.000 18.81837 ? 167 PRO A CB   1 
ATOM   2215 C  CG   . PRO A 1 144 ? -3.09730  6.44260   15.78385 1.000 21.32441 ? 167 PRO A CG   1 
ATOM   2216 C  CD   . PRO A 1 144 ? -3.29113  6.45347   17.29081 1.000 17.75791 ? 167 PRO A CD   1 
ATOM   2217 H  HA   . PRO A 1 144 ? -3.43290  3.35048   16.59493 1.000 22.63599 ? 167 PRO A HA   1 
ATOM   2218 H  HB2  . PRO A 1 144 ? -3.06506  4.79023   14.51793 1.000 22.56197 ? 167 PRO A HB2  1 
ATOM   2219 H  HB3  . PRO A 1 144 ? -4.45060  4.94269   15.28111 1.000 22.56197 ? 167 PRO A HB3  1 
ATOM   2220 H  HG2  . PRO A 1 144 ? -2.17156  6.61480   15.55093 1.000 25.56921 ? 167 PRO A HG2  1 
ATOM   2221 H  HG3  . PRO A 1 144 ? -3.67409  7.09347   15.35422 1.000 25.56921 ? 167 PRO A HG3  1 
ATOM   2222 H  HD2  . PRO A 1 144 ? -2.58053  6.95152   17.72429 1.000 21.28942 ? 167 PRO A HD2  1 
ATOM   2223 H  HD3  . PRO A 1 144 ? -4.15251  6.83431   17.52294 1.000 21.28942 ? 167 PRO A HD3  1 
ATOM   2224 N  N    . THR A 1 145 ? -0.56102  4.32394   17.17087 1.000 17.58242 ? 168 THR A N    1 
ATOM   2225 C  CA   . THR A 1 145 ? 0.86629   4.19760   16.88983 1.000 16.95967 ? 168 THR A CA   1 
ATOM   2226 C  C    . THR A 1 145 ? 1.38760   2.75701   17.03094 1.000 14.76151 ? 168 THR A C    1 
ATOM   2227 O  O    . THR A 1 145 ? 2.46586   2.43186   16.51175 1.000 20.36891 ? 168 THR A O    1 
ATOM   2228 C  CB   . THR A 1 145 ? 1.68346   5.13797   17.79626 1.000 23.92471 ? 168 THR A CB   1 
ATOM   2229 O  OG1  . THR A 1 145 ? 1.50499   4.82442   19.19274 1.000 18.73565 ? 168 THR A OG1  1 
ATOM   2230 C  CG2  . THR A 1 145 ? 1.30691   6.58303   17.56274 1.000 28.62998 ? 168 THR A CG2  1 
ATOM   2231 H  H    . THR A 1 145 ? -0.74497  4.70863   17.91772 1.000 21.07882 ? 168 THR A H    1 
ATOM   2232 H  HA   . THR A 1 145 ? 1.00853   4.47013   15.96983 1.000 20.33153 ? 168 THR A HA   1 
ATOM   2233 H  HB   . THR A 1 145 ? 2.61965   5.01662   17.57328 1.000 28.68958 ? 168 THR A HB   1 
ATOM   2234 H  HG1  . THR A 1 145 ? 1.93284   5.37024   19.66670 1.000 22.46270 ? 168 THR A HG1  1 
ATOM   2235 H  HG21 . THR A 1 145 ? 1.80022   7.15667   18.16976 1.000 34.33590 ? 168 THR A HG21 1 
ATOM   2236 H  HG22 . THR A 1 145 ? 1.51562   6.83694   16.65013 1.000 34.33590 ? 168 THR A HG22 1 
ATOM   2237 H  HG23 . THR A 1 145 ? 0.35692   6.70702   17.71456 1.000 34.33590 ? 168 THR A HG23 1 
ATOM   2238 N  N    . LEU A 1 146 ? 0.65213   1.86292   17.68278 1.000 16.36559 ? 169 LEU A N    1 
ATOM   2239 C  CA   . LEU A 1 146 ? 1.18799   0.51295   17.85385 1.000 17.86670 ? 169 LEU A CA   1 
ATOM   2240 C  C    . LEU A 1 146 ? 1.27607   -0.25885  16.53433 1.000 16.09251 ? 169 LEU A C    1 
ATOM   2241 O  O    . LEU A 1 146 ? 1.83095   -1.37264  16.52593 1.000 17.54564 ? 169 LEU A O    1 
ATOM   2242 C  CB   . LEU A 1 146 ? 0.33852   -0.24942  18.87497 1.000 17.90365 ? 169 LEU A CB   1 
ATOM   2243 C  CG   . LEU A 1 146 ? -1.07567  -0.65366  18.51544 1.000 13.99553 ? 169 LEU A CG   1 
ATOM   2244 C  CD1  . LEU A 1 146 ? -1.04734  -2.02845  17.82724 1.000 18.08651 ? 169 LEU A CD1  1 
ATOM   2245 C  CD2  . LEU A 1 146 ? -1.93081  -0.72319  19.77285 1.000 16.10645 ? 169 LEU A CD2  1 
ATOM   2246 H  H    . LEU A 1 146 ? -0.12569  2.00438   18.02129 1.000 19.61863 ? 169 LEU A H    1 
ATOM   2247 H  HA   . LEU A 1 146 ? 2.08914   0.56750   18.20861 1.000 21.41997 ? 169 LEU A HA   1 
ATOM   2248 H  HB2  . LEU A 1 146 ? 0.81018   -1.06998  19.08738 1.000 21.46430 ? 169 LEU A HB2  1 
ATOM   2249 H  HB3  . LEU A 1 146 ? 0.26927   0.30771   19.66599 1.000 21.46430 ? 169 LEU A HB3  1 
ATOM   2250 H  HG   . LEU A 1 146 ? -1.46550  -0.00092  17.91306 1.000 16.77455 ? 169 LEU A HG   1 
ATOM   2251 H  HD11 . LEU A 1 146 ? -1.95759  -2.34433  17.71516 1.000 21.68373 ? 169 LEU A HD11 1 
ATOM   2252 H  HD12 . LEU A 1 146 ? -0.61913  -1.93944  16.96143 1.000 21.68373 ? 169 LEU A HD12 1 
ATOM   2253 H  HD13 . LEU A 1 146 ? -0.54783  -2.64864  18.38111 1.000 21.68373 ? 169 LEU A HD13 1 
ATOM   2254 H  HD21 . LEU A 1 146 ? -2.83855  -0.95854  19.52482 1.000 19.30766 ? 169 LEU A HD21 1 
ATOM   2255 H  HD22 . LEU A 1 146 ? -1.56488  -1.39719  20.36676 1.000 19.30766 ? 169 LEU A HD22 1 
ATOM   2256 H  HD23 . LEU A 1 146 ? -1.92123  0.14288   20.20957 1.000 19.30766 ? 169 LEU A HD23 1 
ATOM   2257 N  N    . ASN A 1 147 ? 0.77892   0.32114   15.42806 1.000 19.37038 ? 170 ASN A N    1 
ATOM   2258 C  CA   . ASN A 1 147 ? 0.75447   -0.33441  14.12841 1.000 20.60285 ? 170 ASN A CA   1 
ATOM   2259 C  C    . ASN A 1 147 ? 1.84478   0.11198   13.16818 1.000 20.15698 ? 170 ASN A C    1 
ATOM   2260 O  O    . ASN A 1 147 ? 1.77195   -0.24299  11.98710 1.000 18.66943 ? 170 ASN A O    1 
ATOM   2261 C  CB   . ASN A 1 147 ? -0.59666  -0.10320  13.45616 1.000 17.92140 ? 170 ASN A CB   1 
ATOM   2262 C  CG   . ASN A 1 147 ? -1.76208  -0.48745  14.35776 1.000 20.47258 ? 170 ASN A CG   1 
ATOM   2263 O  OD1  . ASN A 1 147 ? -2.01562  -1.66433  14.58672 1.000 19.33025 ? 170 ASN A OD1  1 
ATOM   2264 N  ND2  . ASN A 1 147 ? -2.44400  0.50687   14.89702 1.000 20.16798 ? 170 ASN A ND2  1 
ATOM   2265 H  H    . ASN A 1 147 ? 0.44432   1.11327   15.41482 1.000 23.22437 ? 170 ASN A H    1 
ATOM   2266 H  HA   . ASN A 1 147 ? 0.88694   -1.28068  14.29554 1.000 24.70333 ? 170 ASN A HA   1 
ATOM   2267 H  HB2  . ASN A 1 147 ? -0.68431  0.83673   13.23314 1.000 21.48560 ? 170 ASN A HB2  1 
ATOM   2268 H  HB3  . ASN A 1 147 ? -0.64749  -0.64141  12.65077 1.000 21.48560 ? 170 ASN A HB3  1 
ATOM   2269 H  HD21 . ASN A 1 147 ? -3.11109  0.34038   15.41361 1.000 24.18150 ? 170 ASN A HD21 1 
ATOM   2270 H  HD22 . ASN A 1 147 ? -2.22092  1.32078   14.73155 1.000 24.18150 ? 170 ASN A HD22 1 
ATOM   2271 N  N    . THR A 1 148 ? 2.86422   0.85715   13.62067 1.000 15.94071 ? 171 THR A N    1 
ATOM   2272 C  CA   . THR A 1 148 ? 3.86849   1.34984   12.67207 1.000 16.11290 ? 171 THR A CA   1 
ATOM   2273 C  C    . THR A 1 148 ? 4.63172   0.20889   11.99207 1.000 15.93992 ? 171 THR A C    1 
ATOM   2274 O  O    . THR A 1 148 ? 5.03179   0.33614   10.82219 1.000 16.61944 ? 171 THR A O    1 
ATOM   2275 C  CB   . THR A 1 148 ? 4.83875   2.31223   13.36950 1.000 17.56350 ? 171 THR A CB   1 
ATOM   2276 O  OG1  . THR A 1 148 ? 5.34284   1.74197   14.58732 1.000 18.95555 ? 171 THR A OG1  1 
ATOM   2277 C  CG2  . THR A 1 148 ? 4.13613   3.61591   13.72456 1.000 21.37950 ? 171 THR A CG2  1 
ATOM   2278 H  H    . THR A 1 148 ? 2.99133   1.08228   14.44089 1.000 19.10877 ? 171 THR A H    1 
ATOM   2279 H  HA   . THR A 1 148 ? 3.40983   1.84687   11.97674 1.000 19.31540 ? 171 THR A HA   1 
ATOM   2280 H  HB   . THR A 1 148 ? 5.57486   2.48729   12.76254 1.000 21.05612 ? 171 THR A HB   1 
ATOM   2281 H  HG1  . THR A 1 148 ? 5.80011   1.05831   14.41670 1.000 22.72658 ? 171 THR A HG1  1 
ATOM   2282 H  HG21 . THR A 1 148 ? 4.76000   4.22325   14.15214 1.000 25.63532 ? 171 THR A HG21 1 
ATOM   2283 H  HG22 . THR A 1 148 ? 3.78896   4.03504   12.92163 1.000 25.63532 ? 171 THR A HG22 1 
ATOM   2284 H  HG23 . THR A 1 148 ? 3.40025   3.44143   14.33196 1.000 25.63532 ? 171 THR A HG23 1 
ATOM   2285 N  N    . ALA A 1 149 ? 4.84039   -0.90097  12.68730 1.000 16.12266 ? 172 ALA A N    1 
ATOM   2286 C  CA   . ALA A 1 149 ? 5.40748   -2.13387  12.10619 1.000 18.39993 ? 172 ALA A CA   1 
ATOM   2287 C  C    . ALA A 1 149 ? 6.72135   -1.89765  11.36778 1.000 21.94094 ? 172 ALA A C    1 
ATOM   2288 O  O    . ALA A 1 149 ? 6.97788   -2.46095  10.29313 1.000 19.79764 ? 172 ALA A O    1 
ATOM   2289 C  CB   . ALA A 1 149 ? 4.38769   -2.82827  11.20233 1.000 17.86258 ? 172 ALA A CB   1 
ATOM   2290 H  H    . ALA A 1 149 ? 4.65947   -0.97809  13.52451 1.000 19.32711 ? 172 ALA A H    1 
ATOM   2291 H  HA   . ALA A 1 149 ? 5.62063   -2.72435  12.84565 1.000 22.05983 ? 172 ALA A HA   1 
ATOM   2292 H  HB1  . ALA A 1 149 ? 4.80781   -3.59579  10.78362 1.000 21.41502 ? 172 ALA A HB1  1 
ATOM   2293 H  HB2  . ALA A 1 149 ? 3.63360   -3.11639  11.74013 1.000 21.41502 ? 172 ALA A HB2  1 
ATOM   2294 H  HB3  . ALA A 1 149 ? 4.08996   -2.20278  10.52335 1.000 21.41502 ? 172 ALA A HB3  1 
ATOM   2295 N  N    . ILE A 1 150 ? 7.58680   -1.08838  11.96519 1.000 18.73652 ? 173 ILE A N    1 
ATOM   2296 C  CA   . ILE A 1 150 ? 8.87676   -0.78187  11.33885 1.000 18.33470 ? 173 ILE A CA   1 
ATOM   2297 C  C    . ILE A 1 150 ? 9.77637   -2.01916  11.38965 1.000 21.96750 ? 173 ILE A C    1 
ATOM   2298 O  O    . ILE A 1 150 ? 9.95714   -2.60931  12.46879 1.000 20.94182 ? 173 ILE A O    1 
ATOM   2299 C  CB   . ILE A 1 150 ? 9.53714   0.40675   12.04291 1.000 24.60572 ? 173 ILE A CB   1 
ATOM   2300 C  CG1  . ILE A 1 150 ? 8.64618   1.64021   11.91837 1.000 22.35321 ? 173 ILE A CG1  1 
ATOM   2301 C  CG2  . ILE A 1 150 ? 10.92299  0.61791   11.45669 1.000 27.88448 ? 173 ILE A CG2  1 
ATOM   2302 C  CD1  . ILE A 1 150 ? 8.98370   2.77296   12.94250 1.000 25.49417 ? 173 ILE A CD1  1 
ATOM   2303 H  H    . ILE A 1 150 ? 7.45811   -0.70563  12.72449 1.000 22.46374 ? 173 ILE A H    1 
ATOM   2304 H  HA   . ILE A 1 150 ? 8.73254   -0.55013  10.40804 1.000 21.98156 ? 173 ILE A HA   1 
ATOM   2305 H  HB   . ILE A 1 150 ? 9.64017   0.23002   12.99110 1.000 29.50678 ? 173 ILE A HB   1 
ATOM   2306 H  HG12 . ILE A 1 150 ? 8.74750   2.00850   11.02675 1.000 26.80378 ? 173 ILE A HG12 1 
ATOM   2307 H  HG13 . ILE A 1 150 ? 7.72483   1.37461   12.06490 1.000 26.80378 ? 173 ILE A HG13 1 
ATOM   2308 H  HG21 . ILE A 1 150 ? 11.21305  1.52314   11.64990 1.000 33.44130 ? 173 ILE A HG21 1 
ATOM   2309 H  HG22 . ILE A 1 150 ? 11.53571  -0.01840  11.85744 1.000 33.44130 ? 173 ILE A HG22 1 
ATOM   2310 H  HG23 . ILE A 1 150 ? 10.88431  0.48063   10.49724 1.000 33.44130 ? 173 ILE A HG23 1 
ATOM   2311 H  HD11 . ILE A 1 150 ? 8.38735   3.52298   12.79172 1.000 30.57293 ? 173 ILE A HD11 1 
ATOM   2312 H  HD12 . ILE A 1 150 ? 8.86418   2.43103   13.84233 1.000 30.57293 ? 173 ILE A HD12 1 
ATOM   2313 H  HD13 . ILE A 1 150 ? 9.90403   3.05107   12.81384 1.000 30.57293 ? 173 ILE A HD13 1 
ATOM   2314 N  N    . PRO A 1 151 ? 10.38873  -2.43080  10.28248 1.000 19.38442 ? 174 PRO A N    1 
ATOM   2315 C  CA   . PRO A 1 151 ? 11.31780  -3.57021  10.33565 1.000 24.02365 ? 174 PRO A CA   1 
ATOM   2316 C  C    . PRO A 1 151 ? 12.41709  -3.30457  11.35025 1.000 19.45443 ? 174 PRO A C    1 
ATOM   2317 O  O    . PRO A 1 151 ? 12.95462  -2.20587  11.41994 1.000 26.18143 ? 174 PRO A O    1 
ATOM   2318 C  CB   . PRO A 1 151 ? 11.86177  -3.64099  8.90351  1.000 24.72078 ? 174 PRO A CB   1 
ATOM   2319 C  CG   . PRO A 1 151 ? 10.72327  -3.09894  8.08467  1.000 26.24970 ? 174 PRO A CG   1 
ATOM   2320 C  CD   . PRO A 1 151 ? 10.13420  -1.98678  8.89630  1.000 26.39042 ? 174 PRO A CD   1 
ATOM   2321 H  HA   . PRO A 1 151 ? 10.85975  -4.39806  10.54960 1.000 28.80830 ? 174 PRO A HA   1 
ATOM   2322 H  HB2  . PRO A 1 151 ? 12.65566  -3.09067  8.81529  1.000 29.64486 ? 174 PRO A HB2  1 
ATOM   2323 H  HB3  . PRO A 1 151 ? 12.06578  -4.55849  8.66378  1.000 29.64486 ? 174 PRO A HB3  1 
ATOM   2324 H  HG2  . PRO A 1 151 ? 11.05817  -2.76647  7.23720  1.000 31.47956 ? 174 PRO A HG2  1 
ATOM   2325 H  HG3  . PRO A 1 151 ? 10.06800  -3.79753  7.93138  1.000 31.47956 ? 174 PRO A HG3  1 
ATOM   2326 H  HD2  . PRO A 1 151 ? 10.58238  -1.14645  8.71221  1.000 31.64842 ? 174 PRO A HD2  1 
ATOM   2327 H  HD3  . PRO A 1 151 ? 9.18293   -1.89924  8.72804  1.000 31.64842 ? 174 PRO A HD3  1 
ATOM   2328 N  N    . GLY A 1 152 ? 12.70221  -4.30879  12.17390 1.000 21.92700 ? 175 GLY A N    1 
ATOM   2329 C  CA   . GLY A 1 152 ? 13.68863  -4.18969  13.22727 1.000 32.08096 ? 175 GLY A CA   1 
ATOM   2330 C  C    . GLY A 1 152 ? 13.15990  -3.67728  14.55266 1.000 28.39949 ? 175 GLY A C    1 
ATOM   2331 O  O    . GLY A 1 152 ? 13.87541  -3.75599  15.56042 1.000 28.09293 ? 175 GLY A O    1 
ATOM   2332 H  H    . GLY A 1 152 ? 12.32738  -5.08195  12.13748 1.000 26.29231 ? 175 GLY A H    1 
ATOM   2333 H  HA2  . GLY A 1 152 ? 14.07998  -5.06320  13.38450 1.000 38.47707 ? 175 GLY A HA2  1 
ATOM   2334 H  HA3  . GLY A 1 152 ? 14.38367  -3.58066  12.93249 1.000 38.47707 ? 175 GLY A HA3  1 
ATOM   2335 N  N    . ASP A 1 153 ? 11.95118  -3.14721  14.58796 1.000 22.22275 ? 176 ASP A N    1 
ATOM   2336 C  CA   . ASP A 1 153 ? 11.41467  -2.54250  15.80823 1.000 19.11173 ? 176 ASP A CA   1 
ATOM   2337 C  C    . ASP A 1 153 ? 10.69906  -3.60994  16.63086 1.000 22.04678 ? 176 ASP A C    1 
ATOM   2338 O  O    . ASP A 1 153 ? 9.76149   -4.23433  16.12466 1.000 20.05047 ? 176 ASP A O    1 
ATOM   2339 C  CB   . ASP A 1 153 ? 10.47018  -1.41334  15.43087 1.000 20.35958 ? 176 ASP A CB   1 
ATOM   2340 C  CG   . ASP A 1 153 ? 9.98850   -0.59023  16.60401 1.000 22.31889 ? 176 ASP A CG   1 
ATOM   2341 O  OD1  . ASP A 1 153 ? 10.22148  -0.99938  17.76156 1.000 24.65819 ? 176 ASP A OD1  1 
ATOM   2342 O  OD2  . ASP A 1 153 ? 9.35508   0.47053   16.35048 1.000 23.92479 ? 176 ASP A OD2  1 
ATOM   2343 H  H    . ASP A 1 153 ? 11.41278  -3.12143  13.91785 1.000 26.64722 ? 176 ASP A H    1 
ATOM   2344 H  HA   . ASP A 1 153 ? 12.12359  -2.17992  16.36219 1.000 22.91400 ? 176 ASP A HA   1 
ATOM   2345 H  HB2  . ASP A 1 153 ? 10.92950  -0.81501  14.82101 1.000 24.41141 ? 176 ASP A HB2  1 
ATOM   2346 H  HB3  . ASP A 1 153 ? 9.68951   -1.79302  14.99808 1.000 24.41141 ? 176 ASP A HB3  1 
ATOM   2347 N  N    . PRO A 1 154 ? 11.11950  -3.88401  17.87339 1.000 18.87956 ? 177 PRO A N    1 
ATOM   2348 C  CA   . PRO A 1 154 ? 10.45290  -4.93523  18.65000 1.000 17.30408 ? 177 PRO A CA   1 
ATOM   2349 C  C    . PRO A 1 154 ? 9.17148   -4.49078  19.31394 1.000 20.59604 ? 177 PRO A C    1 
ATOM   2350 O  O    . PRO A 1 154 ? 8.44363   -5.33464  19.84989 1.000 19.62552 ? 177 PRO A O    1 
ATOM   2351 C  CB   . PRO A 1 154 ? 11.53374  -5.32552  19.69132 1.000 21.95835 ? 177 PRO A CB   1 
ATOM   2352 C  CG   . PRO A 1 154 ? 12.21196  -4.03696  19.96411 1.000 19.76486 ? 177 PRO A CG   1 
ATOM   2353 C  CD   . PRO A 1 154 ? 12.31366  -3.36816  18.58129 1.000 22.71201 ? 177 PRO A CD   1 
ATOM   2354 H  HA   . PRO A 1 154 ? 10.26159  -5.70597  18.09299 1.000 20.74481 ? 177 PRO A HA   1 
ATOM   2355 H  HB2  . PRO A 1 154 ? 11.11898  -5.68430  20.49141 1.000 26.32994 ? 177 PRO A HB2  1 
ATOM   2356 H  HB3  . PRO A 1 154 ? 12.14683  -5.97628  19.31512 1.000 26.32994 ? 177 PRO A HB3  1 
ATOM   2357 H  HG2  . PRO A 1 154 ? 11.68027  -3.50162  20.57371 1.000 23.69775 ? 177 PRO A HG2  1 
ATOM   2358 H  HG3  . PRO A 1 154 ? 13.09119  -4.19519  20.34202 1.000 23.69775 ? 177 PRO A HG3  1 
ATOM   2359 H  HD2  . PRO A 1 154 ? 12.27899  -2.40201  18.66040 1.000 27.23434 ? 177 PRO A HD2  1 
ATOM   2360 H  HD3  . PRO A 1 154 ? 13.12795  -3.63478  18.12660 1.000 27.23434 ? 177 PRO A HD3  1 
ATOM   2361 N  N    . ARG A 1 155 ? 8.84862   -3.20619  19.27157 1.000 15.54222 ? 178 ARG A N    1 
ATOM   2362 C  CA   . ARG A 1 155 ? 7.65922   -2.74699  19.96068 1.000 15.09079 ? 178 ARG A CA   1 
ATOM   2363 C  C    . ARG A 1 155 ? 6.40299   -3.39297  19.39424 1.000 21.66549 ? 178 ARG A C    1 
ATOM   2364 O  O    . ARG A 1 155 ? 6.24488   -3.54166  18.18345 1.000 18.50825 ? 178 ARG A O    1 
ATOM   2365 C  CB   . ARG A 1 155 ? 7.56658   -1.21725  19.87023 1.000 16.72571 ? 178 ARG A CB   1 
ATOM   2366 C  CG   . ARG A 1 155 ? 8.70124   -0.47879  20.53051 1.000 19.62277 ? 178 ARG A CG   1 
ATOM   2367 C  CD   . ARG A 1 155 ? 8.50045   1.04046   20.44117 1.000 19.67929 ? 178 ARG A CD   1 
ATOM   2368 N  NE   . ARG A 1 155 ? 8.69281   1.50200   19.06898 1.000 22.45897 ? 178 ARG A NE   1 
ATOM   2369 C  CZ   . ARG A 1 155 ? 8.58867   2.76058   18.67468 1.000 22.58505 ? 178 ARG A CZ   1 
ATOM   2370 N  NH1  . ARG A 1 155 ? 8.21402   3.70976   19.50849 1.000 20.79105 ? 178 ARG A NH1  1 
ATOM   2371 N  NH2  . ARG A 1 155 ? 8.88031   3.07354   17.40947 1.000 17.60447 ? 178 ARG A NH2  1 
ATOM   2372 H  H    . ARG A 1 155 ? 9.29261   -2.59562  18.85966 1.000 18.63059 ? 178 ARG A H    1 
ATOM   2373 H  HA   . ARG A 1 155 ? 7.71457   -2.99909  20.89571 1.000 18.08887 ? 178 ARG A HA   1 
ATOM   2374 H  HB2  . ARG A 1 155 ? 7.55840   -0.96371  18.93399 1.000 20.05077 ? 178 ARG A HB2  1 
ATOM   2375 H  HB3  . ARG A 1 155 ? 6.74408   -0.93236  20.29829 1.000 20.05077 ? 178 ARG A HB3  1 
ATOM   2376 H  HG2  . ARG A 1 155 ? 8.74608   -0.72721  21.46709 1.000 23.52724 ? 178 ARG A HG2  1 
ATOM   2377 H  HG3  . ARG A 1 155 ? 9.53407   -0.70421  20.08725 1.000 23.52724 ? 178 ARG A HG3  1 
ATOM   2378 H  HD2  . ARG A 1 155 ? 7.59913   1.26600   20.71983 1.000 23.59507 ? 178 ARG A HD2  1 
ATOM   2379 H  HD3  . ARG A 1 155 ? 9.14558   1.48751   21.01113 1.000 23.59507 ? 178 ARG A HD3  1 
ATOM   2380 H  HE   . ARG A 1 155 ? 8.88802   0.91267   18.47385 1.000 26.93069 ? 178 ARG A HE   1 
ATOM   2381 H  HH11 . ARG A 1 155 ? 8.03178   3.51633   20.32640 1.000 24.92917 ? 178 ARG A HH11 1 
ATOM   2382 H  HH12 . ARG A 1 155 ? 8.15175   4.52265   19.23474 1.000 24.92917 ? 178 ARG A HH12 1 
ATOM   2383 H  HH21 . ARG A 1 155 ? 9.13231   2.46012   16.86192 1.000 21.10528 ? 178 ARG A HH21 1 
ATOM   2384 H  HH22 . ARG A 1 155 ? 8.81610   3.88847   17.14234 1.000 21.10528 ? 178 ARG A HH22 1 
ATOM   2385 N  N    . ASP A 1 156 ? 5.49513   -3.78346  20.28820 1.000 14.50145 ? 179 ASP A N    1 
ATOM   2386 C  CA   . ASP A 1 156 ? 4.16849   -4.24458  19.86345 1.000 15.77234 ? 179 ASP A CA   1 
ATOM   2387 C  C    . ASP A 1 156 ? 4.29260   -5.45561  18.95217 1.000 15.79887 ? 179 ASP A C    1 
ATOM   2388 O  O    . ASP A 1 156 ? 3.56463   -5.59440  17.95838 1.000 14.94240 ? 179 ASP A O    1 
ATOM   2389 C  CB   . ASP A 1 156 ? 3.40343   -3.11792  19.18132 1.000 17.66411 ? 179 ASP A CB   1 
ATOM   2390 C  CG   . ASP A 1 156 ? 3.37418   -1.86558  20.02586 1.000 14.68718 ? 179 ASP A CG   1 
ATOM   2391 O  OD1  . ASP A 1 156 ? 2.70261   -1.90720  21.09510 1.000 15.97572 ? 179 ASP A OD1  1 
ATOM   2392 O  OD2  . ASP A 1 156 ? 4.00733   -0.85604  19.61819 1.000 15.09006 ? 179 ASP A OD2  1 
ATOM   2393 H  H    . ASP A 1 156 ? 5.62021   -3.79127  21.13902 1.000 17.38166 ? 179 ASP A H    1 
ATOM   2394 H  HA   . ASP A 1 156 ? 3.65942   -4.51823  20.64246 1.000 18.90673 ? 179 ASP A HA   1 
ATOM   2395 H  HB2  . ASP A 1 156 ? 3.83249   -2.90537  18.33774 1.000 21.17685 ? 179 ASP A HB2  1 
ATOM   2396 H  HB3  . ASP A 1 156 ? 2.48872   -3.40103  19.02623 1.000 21.17685 ? 179 ASP A HB3  1 
ATOM   2397 N  N    . THR A 1 157 ? 5.22224   -6.33897  19.30022 1.000 13.45366 ? 180 THR A N    1 
ATOM   2398 C  CA   . THR A 1 157 ? 5.45898   -7.56422  18.56684 1.000 14.48681 ? 180 THR A CA   1 
ATOM   2399 C  C    . THR A 1 157 ? 5.22816   -8.79903  19.43575 1.000 15.91222 ? 180 THR A C    1 
ATOM   2400 O  O    . THR A 1 157 ? 5.20492   -8.74603  20.68075 1.000 15.82062 ? 180 THR A O    1 
ATOM   2401 C  CB   . THR A 1 157 ? 6.87099   -7.65383  18.03019 1.000 19.03606 ? 180 THR A CB   1 
ATOM   2402 O  OG1  . THR A 1 157 ? 7.79470   -7.68253  19.12442 1.000 17.25879 ? 180 THR A OG1  1 
ATOM   2403 C  CG2  . THR A 1 157 ? 7.23389   -6.49126  17.12479 1.000 15.54025 ? 180 THR A CG2  1 
ATOM   2404 H  H    . THR A 1 157 ? 5.74130   -6.24255  19.97910 1.000 16.12431 ? 180 THR A H    1 
ATOM   2405 H  HA   . THR A 1 157 ? 4.82585   -7.56810  17.83197 1.000 17.36409 ? 180 THR A HA   1 
ATOM   2406 H  HB   . THR A 1 157 ? 6.93445   -8.46320  17.49935 1.000 22.82319 ? 180 THR A HB   1 
ATOM   2407 H  HG1  . THR A 1 157 ? 7.71944   -6.98238  19.58237 1.000 20.69047 ? 180 THR A HG1  1 
ATOM   2408 H  HG21 . THR A 1 157 ? 8.12979   -6.61181  16.77302 1.000 18.62822 ? 180 THR A HG21 1 
ATOM   2409 H  HG22 . THR A 1 157 ? 6.60928   -6.43979  16.38444 1.000 18.62822 ? 180 THR A HG22 1 
ATOM   2410 H  HG23 . THR A 1 157 ? 7.20062   -5.65971  17.62312 1.000 18.62822 ? 180 THR A HG23 1 
ATOM   2411 N  N    . THR A 1 158 ? 5.09233   -9.92932  18.75292 1.000 12.98240 ? 181 THR A N    1 
ATOM   2412 C  CA   . THR A 1 158 ? 5.18533   -11.25081 19.34232 1.000 14.04879 ? 181 THR A CA   1 
ATOM   2413 C  C    . THR A 1 158 ? 5.61954   -12.19494 18.23044 1.000 15.73596 ? 181 THR A C    1 
ATOM   2414 O  O    . THR A 1 158 ? 5.83112   -11.77591 17.08451 1.000 15.65434 ? 181 THR A O    1 
ATOM   2415 C  CB   . THR A 1 158 ? 3.85774   -11.68473 19.97867 1.000 15.32189 ? 181 THR A CB   1 
ATOM   2416 O  OG1  . THR A 1 158 ? 4.09297   -12.78195 20.86098 1.000 14.80450 ? 181 THR A OG1  1 
ATOM   2417 C  CG2  . THR A 1 158 ? 2.85021   -12.08296 18.93858 1.000 13.31218 ? 181 THR A CG2  1 
ATOM   2418 H  H    . THR A 1 158 ? 4.93858   -9.95480  17.90716 1.000 15.55880 ? 181 THR A H    1 
ATOM   2419 H  HA   . THR A 1 158 ? 5.85031   -11.25246 20.04851 1.000 16.83846 ? 181 THR A HA   1 
ATOM   2420 H  HB   . THR A 1 158 ? 3.48512   -10.93796 20.47303 1.000 18.36619 ? 181 THR A HB   1 
ATOM   2421 H  HG1  . THR A 1 158 ? 3.36887   -13.03653 21.20225 1.000 17.74532 ? 181 THR A HG1  1 
ATOM   2422 H  HG21 . THR A 1 158 ? 1.96910   -12.14984 19.33867 1.000 15.95454 ? 181 THR A HG21 1 
ATOM   2423 H  HG22 . THR A 1 158 ? 2.82492   -11.42057 18.23041 1.000 15.95454 ? 181 THR A HG22 1 
ATOM   2424 H  HG23 . THR A 1 158 ? 3.08890   -12.94238 18.55737 1.000 15.95454 ? 181 THR A HG23 1 
ATOM   2425 N  N    . SER A 1 159 ? 5.80721   -13.47487 18.58278 1.000 15.43115 ? 182 SER A N    1 
ATOM   2426 C  CA   . SER A 1 159 ? 6.17588   -14.48424 17.59750 1.000 13.39319 ? 182 SER A CA   1 
ATOM   2427 C  C    . SER A 1 159 ? 4.95105   -15.31659 17.25917 1.000 17.01797 ? 182 SER A C    1 
ATOM   2428 O  O    . SER A 1 159 ? 4.00114   -15.38611 18.05019 1.000 17.99806 ? 182 SER A O    1 
ATOM   2429 C  CB   . SER A 1 159 ? 7.26889   -15.41264 18.13551 1.000 15.76724 ? 182 SER A CB   1 
ATOM   2430 O  OG   . SER A 1 159 ? 6.68585   -16.25163 19.11144 1.000 15.91391 ? 182 SER A OG   1 
ATOM   2431 H  H    . SER A 1 159 ? 5.72550   -13.77474 19.38465 1.000 18.49730 ? 182 SER A H    1 
ATOM   2432 H  HA   . SER A 1 159 ? 6.52276   -14.05239 16.80120 1.000 16.05174 ? 182 SER A HA   1 
ATOM   2433 H  HB2  . SER A 1 159 ? 7.62608   -15.95121 17.41214 1.000 18.90061 ? 182 SER A HB2  1 
ATOM   2434 H  HB3  . SER A 1 159 ? 7.97703   -14.88574 18.53777 1.000 18.90061 ? 182 SER A HB3  1 
ATOM   2435 H  HG   . SER A 1 159 ? 7.26343   -16.77758 19.42028 1.000 19.07661 ? 182 SER A HG   1 
ATOM   2436 N  N    . PRO A 1 160 ? 4.93689   -16.00332 16.11286 1.000 16.93382 ? 183 PRO A N    1 
ATOM   2437 C  CA   . PRO A 1 160 ? 3.79716   -16.89967 15.83678 1.000 14.08894 ? 183 PRO A CA   1 
ATOM   2438 C  C    . PRO A 1 160 ? 3.62801   -18.03481 16.83822 1.000 14.72163 ? 183 PRO A C    1 
ATOM   2439 O  O    . PRO A 1 160 ? 2.50160   -18.33181 17.25329 1.000 17.76481 ? 183 PRO A O    1 
ATOM   2440 C  CB   . PRO A 1 160 ? 4.10367   -17.42463 14.41271 1.000 14.15629 ? 183 PRO A CB   1 
ATOM   2441 C  CG   . PRO A 1 160 ? 4.88104   -16.28065 13.76429 1.000 17.67542 ? 183 PRO A CG   1 
ATOM   2442 C  CD   . PRO A 1 160 ? 5.79086   -15.80078 14.91973 1.000 17.33017 ? 183 PRO A CD   1 
ATOM   2443 H  HA   . PRO A 1 160 ? 2.98007   -16.37705 15.82537 1.000 16.88665 ? 183 PRO A HA   1 
ATOM   2444 H  HB2  . PRO A 1 160 ? 4.64000   -18.23143 14.46099 1.000 16.96747 ? 183 PRO A HB2  1 
ATOM   2445 H  HB3  . PRO A 1 160 ? 3.27786   -17.60324 13.93623 1.000 16.96747 ? 183 PRO A HB3  1 
ATOM   2446 H  HG2  . PRO A 1 160 ? 5.40126   -16.60481 13.01249 1.000 21.19043 ? 183 PRO A HG2  1 
ATOM   2447 H  HG3  . PRO A 1 160 ? 4.27692   -15.58018 13.47227 1.000 21.19043 ? 183 PRO A HG3  1 
ATOM   2448 H  HD2  . PRO A 1 160 ? 6.59646   -16.33834 14.97378 1.000 20.77612 ? 183 PRO A HD2  1 
ATOM   2449 H  HD3  . PRO A 1 160 ? 6.02298   -14.86497 14.81344 1.000 20.77612 ? 183 PRO A HD3  1 
ATOM   2450 N  N    . ARG A 1 161 ? 4.71863   -18.67557 17.25646 1.000 15.79108 ? 184 ARG A N    1 
ATOM   2451 C  CA   . ARG A 1 161 ? 4.62537   -19.75544 18.22425 1.000 13.63226 ? 184 ARG A CA   1 
ATOM   2452 C  C    . ARG A 1 161 ? 3.97079   -19.28202 19.52096 1.000 18.00954 ? 184 ARG A C    1 
ATOM   2453 O  O    . ARG A 1 161 ? 3.10307   -19.96120 20.09009 1.000 18.01709 ? 184 ARG A O    1 
ATOM   2454 C  CB   . ARG A 1 161 ? 6.01966   -20.29272 18.51092 1.000 14.19871 ? 184 ARG A CB   1 
ATOM   2455 C  CG   . ARG A 1 161 ? 6.03984   -21.56245 19.38948 1.000 19.05553 ? 184 ARG A CG   1 
ATOM   2456 C  CD   . ARG A 1 161 ? 7.41239   -21.83814 20.05738 1.000 20.43521 ? 184 ARG A CD   1 
ATOM   2457 N  NE   . ARG A 1 161 ? 8.49524   -22.14246 19.12145 1.000 20.16725 ? 184 ARG A NE   1 
ATOM   2458 C  CZ   . ARG A 1 161 ? 8.84863   -23.36059 18.72626 1.000 29.06121 ? 184 ARG A CZ   1 
ATOM   2459 N  NH1  . ARG A 1 161 ? 8.17728   -24.43200 19.10511 1.000 23.57919 ? 184 ARG A NH1  1 
ATOM   2460 N  NH2  . ARG A 1 161 ? 9.92141   -23.50925 17.94701 1.000 22.68317 ? 184 ARG A NH2  1 
ATOM   2461 H  H    . ARG A 1 161 ? 5.51930   -18.50263 16.99450 1.000 18.92922 ? 184 ARG A H    1 
ATOM   2462 H  HA   . ARG A 1 161 ? 4.08015   -20.46639 17.85251 1.000 16.33864 ? 184 ARG A HA   1 
ATOM   2463 H  HB2  . ARG A 1 161 ? 6.44725   -20.51112 17.66809 1.000 17.01837 ? 184 ARG A HB2  1 
ATOM   2464 H  HB3  . ARG A 1 161 ? 6.52735   -19.60719 18.97265 1.000 17.01837 ? 184 ARG A HB3  1 
ATOM   2465 H  HG2  . ARG A 1 161 ? 5.38214   -21.46454 20.09569 1.000 22.84656 ? 184 ARG A HG2  1 
ATOM   2466 H  HG3  . ARG A 1 161 ? 5.82128   -22.32883 18.83650 1.000 22.84656 ? 184 ARG A HG3  1 
ATOM   2467 H  HD2  . ARG A 1 161 ? 7.67451   -21.05182 20.56126 1.000 24.50217 ? 184 ARG A HD2  1 
ATOM   2468 H  HD3  . ARG A 1 161 ? 7.31928   -22.59804 20.65302 1.000 24.50217 ? 184 ARG A HD3  1 
ATOM   2469 H  HE   . ARG A 1 161 ? 8.93887   -21.47894 18.80122 1.000 24.18062 ? 184 ARG A HE   1 
ATOM   2470 H  HH11 . ARG A 1 161 ? 7.49319   -24.35104 19.61996 1.000 28.27494 ? 184 ARG A HH11 1 
ATOM   2471 H  HH12 . ARG A 1 161 ? 8.42394   -25.21106 18.83709 1.000 28.27494 ? 184 ARG A HH12 1 
ATOM   2472 H  HH21 . ARG A 1 161 ? 10.37631  -22.82049 17.70562 1.000 27.19972 ? 184 ARG A HH21 1 
ATOM   2473 H  HH22 . ARG A 1 161 ? 10.15797  -24.29384 17.68612 1.000 27.19972 ? 184 ARG A HH22 1 
ATOM   2474 N  N    . ALA A 1 162 ? 4.42735   -18.14350 20.03703 1.000 16.93295 ? 185 ALA A N    1 
ATOM   2475 C  CA   . ALA A 1 162 ? 3.88671   -17.65164 21.30105 1.000 17.86029 ? 185 ALA A CA   1 
ATOM   2476 C  C    . ALA A 1 162 ? 2.41324   -17.28496 21.17521 1.000 14.37592 ? 185 ALA A C    1 
ATOM   2477 O  O    . ALA A 1 162 ? 1.61704   -17.56972 22.07377 1.000 16.98292 ? 185 ALA A O    1 
ATOM   2478 C  CB   . ALA A 1 162 ? 4.67183   -16.43467 21.79165 1.000 16.51479 ? 185 ALA A CB   1 
ATOM   2479 H  H    . ALA A 1 162 ? 5.03528   -17.64792 19.68430 1.000 20.29946 ? 185 ALA A H    1 
ATOM   2480 H  HA   . ALA A 1 162 ? 3.97955   -18.36131 21.95577 1.000 21.41227 ? 185 ALA A HA   1 
ATOM   2481 H  HB1  . ALA A 1 162 ? 4.30361   -16.14236 22.64010 1.000 19.79767 ? 185 ALA A HB1  1 
ATOM   2482 H  HB2  . ALA A 1 162 ? 5.60274   -16.68340 21.90317 1.000 19.79767 ? 185 ALA A HB2  1 
ATOM   2483 H  HB3  . ALA A 1 162 ? 4.59557   -15.72423 21.13563 1.000 19.79767 ? 185 ALA A HB3  1 
ATOM   2484 N  N    A MET A 1 163 ? 2.02845   -16.61571 20.08733 0.302 14.95392 ? 186 MET A N    1 
ATOM   2485 N  N    B MET A 1 163 ? 2.02767   -16.61744 20.08523 0.698 14.91366 ? 186 MET A N    1 
ATOM   2486 C  CA   A MET A 1 163 ? 0.63590   -16.19971 19.98093 0.302 16.46892 ? 186 MET A CA   1 
ATOM   2487 C  CA   B MET A 1 163 ? 0.63625   -16.20494 19.98032 0.698 16.47305 ? 186 MET A CA   1 
ATOM   2488 C  C    A MET A 1 163 ? -0.28287  -17.39272 19.76247 0.302 16.15316 ? 186 MET A C    1 
ATOM   2489 C  C    B MET A 1 163 ? -0.27963  -17.39903 19.77360 0.698 16.14936 ? 186 MET A C    1 
ATOM   2490 O  O    A MET A 1 163 ? -1.42869  -17.38514 20.23261 0.302 15.67902 ? 186 MET A O    1 
ATOM   2491 O  O    B MET A 1 163 ? -1.42236  -17.39223 20.25680 0.698 15.69136 ? 186 MET A O    1 
ATOM   2492 C  CB   A MET A 1 163 ? 0.47047   -15.17864 18.85282 0.302 14.31533 ? 186 MET A CB   1 
ATOM   2493 C  CB   B MET A 1 163 ? 0.47106   -15.18660 18.84225 0.698 14.26445 ? 186 MET A CB   1 
ATOM   2494 C  CG   A MET A 1 163 ? -0.91211  -14.53255 18.80981 0.302 12.93245 ? 186 MET A CG   1 
ATOM   2495 C  CG   B MET A 1 163 ? -0.85015  -14.40368 18.87210 0.698 12.79323 ? 186 MET A CG   1 
ATOM   2496 S  SD   A MET A 1 163 ? -1.33954  -13.68225 20.34937 0.302 16.69805 ? 186 MET A SD   1 
ATOM   2497 S  SD   B MET A 1 163 ? -1.06171  -13.48522 20.42709 0.698 16.35129 ? 186 MET A SD   1 
ATOM   2498 C  CE   A MET A 1 163 ? -1.10401  -11.98576 19.85529 0.302 12.58798 ? 186 MET A CE   1 
ATOM   2499 C  CE   B MET A 1 163 ? -2.49837  -14.26033 21.15921 0.698 17.27658 ? 186 MET A CE   1 
ATOM   2500 H  H    A MET A 1 163 ? 2.53412   -16.40018 19.42594 0.302 17.92462 ? 186 MET A H    1 
ATOM   2501 H  H    B MET A 1 163 ? 2.53277   -16.40216 19.42332 0.698 17.87631 ? 186 MET A H    1 
ATOM   2502 H  HA   A MET A 1 163 ? 0.38148   -15.75873 20.80658 0.302 19.74262 ? 186 MET A HA   1 
ATOM   2503 H  HA   B MET A 1 163 ? 0.37963   -15.75965 20.80298 0.698 19.74758 ? 186 MET A HA   1 
ATOM   2504 H  HB2  A MET A 1 163 ? 1.12440   -14.47228 18.97262 0.302 17.15831 ? 186 MET A HB2  1 
ATOM   2505 H  HB2  B MET A 1 163 ? 1.19421   -14.54244 18.89718 0.698 17.09726 ? 186 MET A HB2  1 
ATOM   2506 H  HB3  A MET A 1 163 ? 0.61591   -15.62489 18.00393 0.302 17.15831 ? 186 MET A HB3  1 
ATOM   2507 H  HB3  B MET A 1 163 ? 0.51177   -15.65975 17.99646 0.698 17.09726 ? 186 MET A HB3  1 
ATOM   2508 H  HG2  A MET A 1 163 ? -0.93370  -13.88076 18.09176 0.302 15.49886 ? 186 MET A HG2  1 
ATOM   2509 H  HG2  B MET A 1 163 ? -0.86053  -13.76727 18.14013 0.698 15.33180 ? 186 MET A HG2  1 
ATOM   2510 H  HG3  A MET A 1 163 ? -1.57740  -15.22086 18.65320 0.302 15.49886 ? 186 MET A HG3  1 
ATOM   2511 H  HG3  B MET A 1 163 ? -1.59064  -15.02388 18.78302 0.698 15.33180 ? 186 MET A HG3  1 
ATOM   2512 H  HE1  A MET A 1 163 ? -1.12223  -11.42165 20.64418 0.302 15.08550 ? 186 MET A HE1  1 
ATOM   2513 H  HE1  B MET A 1 163 ? -2.73745  -13.78181 21.96839 0.698 20.71182 ? 186 MET A HE1  1 
ATOM   2514 H  HE2  A MET A 1 163 ? -0.24671  -11.90289 19.40912 0.302 15.08550 ? 186 MET A HE2  1 
ATOM   2515 H  HE2  B MET A 1 163 ? -3.23241  -14.22681 20.52599 0.698 20.71182 ? 186 MET A HE2  1 
ATOM   2516 H  HE3  A MET A 1 163 ? -1.81791  -11.73110 19.24999 0.302 15.08550 ? 186 MET A HE3  1 
ATOM   2517 H  HE3  B MET A 1 163 ? -2.28604  -15.18281 21.37095 0.698 20.71182 ? 186 MET A HE3  1 
ATOM   2518 N  N    . ALA A 1 164 ? 0.19509   -18.42268 19.05888 1.000 14.66679 ? 187 ALA A N    1 
ATOM   2519 C  CA   . ALA A 1 164 ? -0.61619  -19.62320 18.85981 1.000 12.67341 ? 187 ALA A CA   1 
ATOM   2520 C  C    . ALA A 1 164 ? -0.78641  -20.35172 20.18671 1.000 18.31974 ? 187 ALA A C    1 
ATOM   2521 O  O    . ALA A 1 164 ? -1.89595  -20.73070 20.56822 1.000 15.58454 ? 187 ALA A O    1 
ATOM   2522 C  CB   . ALA A 1 164 ? 0.01911   -20.52498 17.79472 1.000 17.36820 ? 187 ALA A CB   1 
ATOM   2523 H  H    A ALA A 1 164 ? 0.97274   -18.45074 18.69270 0.302 17.58007 ? 187 ALA A H    1 
ATOM   2524 H  H    B ALA A 1 164 ? 0.96950   -18.44648 18.68562 0.698 17.58007 ? 187 ALA A H    1 
ATOM   2525 H  HA   . ALA A 1 164 ? -1.49457  -19.38103 18.52707 1.000 15.18801 ? 187 ALA A HA   1 
ATOM   2526 H  HB1  . ALA A 1 164 ? -0.53408  -21.31308 17.67737 1.000 20.82176 ? 187 ALA A HB1  1 
ATOM   2527 H  HB2  . ALA A 1 164 ? 0.07765   -20.03463 16.95983 1.000 20.82176 ? 187 ALA A HB2  1 
ATOM   2528 H  HB3  . ALA A 1 164 ? 0.90628   -20.78438 18.08888 1.000 20.82176 ? 187 ALA A HB3  1 
ATOM   2529 N  N    . GLN A 1 165 ? 0.28876   -20.48407 20.94141 1.000 15.46657 ? 188 GLN A N    1 
ATOM   2530 C  CA   . GLN A 1 165 ? 0.17905   -21.14158 22.23800 1.000 16.22249 ? 188 GLN A CA   1 
ATOM   2531 C  C    . GLN A 1 165 ? -0.71340  -20.34147 23.17229 1.000 17.47388 ? 188 GLN A C    1 
ATOM   2532 O  O    . GLN A 1 165 ? -1.55078  -20.91353 23.88924 1.000 17.74412 ? 188 GLN A O    1 
ATOM   2533 C  CB   . GLN A 1 165 ? 1.57503   -21.33301 22.83041 1.000 15.51690 ? 188 GLN A CB   1 
ATOM   2534 C  CG   . GLN A 1 165 ? 2.38672   -22.31373 22.09153 1.000 14.38558 ? 188 GLN A CG   1 
ATOM   2535 C  CD   . GLN A 1 165 ? 1.94162   -23.77628 22.33729 1.000 31.99363 ? 188 GLN A CD   1 
ATOM   2536 O  OE1  . GLN A 1 165 ? 0.99841   -24.04317 23.09362 1.000 24.89024 ? 188 GLN A OE1  1 
ATOM   2537 N  NE2  . GLN A 1 165 ? 2.63202   -24.71774 21.70182 1.000 40.70362 ? 188 GLN A NE2  1 
ATOM   2538 H  H    . GLN A 1 165 ? 1.07755   -20.21015 20.73557 1.000 18.53980 ? 188 GLN A H    1 
ATOM   2539 H  HA   . GLN A 1 165 ? -0.21981  -22.01916 22.13007 1.000 19.44691 ? 188 GLN A HA   1 
ATOM   2540 H  HB2  . GLN A 1 165 ? 2.04315   -20.48363 22.81268 1.000 18.60020 ? 188 GLN A HB2  1 
ATOM   2541 H  HB3  . GLN A 1 165 ? 1.48835   -21.64502 23.74475 1.000 18.60020 ? 188 GLN A HB3  1 
ATOM   2542 H  HG2  . GLN A 1 165 ? 2.31050   -22.13386 21.14141 1.000 17.24262 ? 188 GLN A HG2  1 
ATOM   2543 H  HG3  . GLN A 1 165 ? 3.31182   -22.23189 22.37152 1.000 17.24262 ? 188 GLN A HG3  1 
ATOM   2544 H  HE21 . GLN A 1 165 ? 3.28586   -24.49854 21.18798 1.000 48.82426 ? 188 GLN A HE21 1 
ATOM   2545 H  HE22 . GLN A 1 165 ? 2.42485   -25.54608 21.80452 1.000 48.82426 ? 188 GLN A HE22 1 
ATOM   2546 N  N    . THR A 1 166 ? -0.57803  -19.01536 23.16215 1.000 17.54199 ? 189 THR A N    1 
ATOM   2547 C  CA   . THR A 1 166 ? -1.43048  -18.20207 24.02639 1.000 14.07676 ? 189 THR A CA   1 
ATOM   2548 C  C    . THR A 1 166 ? -2.87774  -18.24363 23.55027 1.000 16.99679 ? 189 THR A C    1 
ATOM   2549 O  O    . THR A 1 166 ? -3.78871  -18.40106 24.35858 1.000 16.39676 ? 189 THR A O    1 
ATOM   2550 C  CB   . THR A 1 166 ? -0.89253  -16.77348 24.10071 1.000 15.54614 ? 189 THR A CB   1 
ATOM   2551 O  OG1  . THR A 1 166 ? 0.35401   -16.83103 24.82717 1.000 18.25125 ? 189 THR A OG1  1 
ATOM   2552 C  CG2  . THR A 1 166 ? -1.88201  -15.87914 24.86806 1.000 22.51936 ? 189 THR A CG2  1 
ATOM   2553 H  H    . THR A 1 166 ? -0.01821  -18.57561 22.67963 1.000 21.03030 ? 189 THR A H    1 
ATOM   2554 H  HA   . THR A 1 166 ? -1.41164  -18.55596 24.92933 1.000 16.87204 ? 189 THR A HA   1 
ATOM   2555 H  HB   . THR A 1 166 ? -0.76616  -16.39462 23.21674 1.000 18.63529 ? 189 THR A HB   1 
ATOM   2556 H  HG1  . THR A 1 166 ? 0.70611   -16.06888 24.85441 1.000 21.88142 ? 189 THR A HG1  1 
ATOM   2557 H  HG21 . THR A 1 166 ? -1.40036  -15.18785 25.34871 1.000 27.00315 ? 189 THR A HG21 1 
ATOM   2558 H  HG22 . THR A 1 166 ? -2.49946  -15.45987 24.24849 1.000 27.00315 ? 189 THR A HG22 1 
ATOM   2559 H  HG23 . THR A 1 166 ? -2.38621  -16.41124 25.50332 1.000 27.00315 ? 189 THR A HG23 1 
ATOM   2560 N  N    . LEU A 1 167 ? -3.11401  -18.20678 22.24265 1.000 15.17487 ? 190 LEU A N    1 
ATOM   2561 C  CA   . LEU A 1 167 ? -4.49723  -18.26282 21.78032 1.000 13.97759 ? 190 LEU A CA   1 
ATOM   2562 C  C    . LEU A 1 167 ? -5.12068  -19.60099 22.13000 1.000 14.72722 ? 190 LEU A C    1 
ATOM   2563 O  O    . LEU A 1 167 ? -6.31266  -19.67107 22.44427 1.000 19.04859 ? 190 LEU A O    1 
ATOM   2564 C  CB   . LEU A 1 167 ? -4.59292  -18.00371 20.27858 1.000 14.70618 ? 190 LEU A CB   1 
ATOM   2565 C  CG   . LEU A 1 167 ? -6.00988  -17.72444 19.79271 1.000 16.22539 ? 190 LEU A CG   1 
ATOM   2566 C  CD1  . LEU A 1 167 ? -6.62826  -16.44976 20.34046 1.000 20.08433 ? 190 LEU A CD1  1 
ATOM   2567 C  CD2  . LEU A 1 167 ? -5.96323  -17.66005 18.21883 1.000 17.02605 ? 190 LEU A CD2  1 
ATOM   2568 H  H    . LEU A 1 167 ? -2.51664  -18.15176 21.62644 1.000 18.18976 ? 190 LEU A H    1 
ATOM   2569 H  HA   . LEU A 1 167 ? -4.99666  -17.55611 22.21851 1.000 16.75302 ? 190 LEU A HA   1 
ATOM   2570 H  HB2  . LEU A 1 167 ? -4.04697  -17.23215 20.06057 1.000 17.62733 ? 190 LEU A HB2  1 
ATOM   2571 H  HB3  . LEU A 1 167 ? -4.26602  -18.78550 19.80651 1.000 17.62733 ? 190 LEU A HB3  1 
ATOM   2572 H  HG   . LEU A 1 167 ? -6.58487  -18.43556 20.11610 1.000 19.45038 ? 190 LEU A HG   1 
ATOM   2573 H  HD11 . LEU A 1 167 ? -7.46971  -16.28651 19.88635 1.000 24.08111 ? 190 LEU A HD11 1 
ATOM   2574 H  HD12 . LEU A 1 167 ? -6.78140  -16.55674 21.29230 1.000 24.08111 ? 190 LEU A HD12 1 
ATOM   2575 H  HD13 . LEU A 1 167 ? -6.01938  -15.71097 20.18437 1.000 24.08111 ? 190 LEU A HD13 1 
ATOM   2576 H  HD21 . LEU A 1 167 ? -6.86116  -17.51470 17.88196 1.000 20.41118 ? 190 LEU A HD21 1 
ATOM   2577 H  HD22 . LEU A 1 167 ? -5.38644  -16.92809 17.94967 1.000 20.41118 ? 190 LEU A HD22 1 
ATOM   2578 H  HD23 . LEU A 1 167 ? -5.61403  -18.49865 17.87867 1.000 20.41118 ? 190 LEU A HD23 1 
ATOM   2579 N  N    A ARG A 1 168 ? -4.32862  -20.67521 22.11178 0.478 16.30472 ? 191 ARG A N    1 
ATOM   2580 N  N    C ARG A 1 168 ? -4.33092  -20.68232 22.06934 0.522 16.32763 ? 191 ARG A N    1 
ATOM   2581 C  CA   A ARG A 1 168 ? -4.86855  -21.97032 22.49695 0.478 17.46956 ? 191 ARG A CA   1 
ATOM   2582 C  CA   C ARG A 1 168 ? -4.83650  -21.98076 22.49885 0.522 17.44721 ? 191 ARG A CA   1 
ATOM   2583 C  C    A ARG A 1 168 ? -5.26559  -21.98116 23.96784 0.478 18.71775 ? 191 ARG A C    1 
ATOM   2584 C  C    C ARG A 1 168 ? -5.29263  -21.91234 23.95127 0.522 18.71442 ? 191 ARG A C    1 
ATOM   2585 O  O    A ARG A 1 168 ? -6.31883  -22.51467 24.33267 0.478 19.11660 ? 191 ARG A O    1 
ATOM   2586 O  O    C ARG A 1 168 ? -6.41419  -22.30386 24.28904 0.522 19.08626 ? 191 ARG A O    1 
ATOM   2587 C  CB   A ARG A 1 168 ? -3.85547  -23.06688 22.20758 0.478 17.26475 ? 191 ARG A CB   1 
ATOM   2588 C  CB   C ARG A 1 168 ? -3.76965  -23.06534 22.32418 0.522 17.29447 ? 191 ARG A CB   1 
ATOM   2589 C  CG   A ARG A 1 168 ? -4.39374  -24.43426 22.56910 0.478 17.65343 ? 191 ARG A CG   1 
ATOM   2590 C  CG   C ARG A 1 168 ? -4.26285  -24.43973 22.81774 0.522 17.87441 ? 191 ARG A CG   1 
ATOM   2591 C  CD   A ARG A 1 168 ? -3.83893  -24.90585 23.89489 0.478 20.15168 ? 191 ARG A CD   1 
ATOM   2592 C  CD   C ARG A 1 168 ? -3.23415  -25.59134 22.75721 0.522 15.23902 ? 191 ARG A CD   1 
ATOM   2593 N  NE   A ARG A 1 168 ? -2.42431  -25.22169 23.73961 0.478 21.34908 ? 191 ARG A NE   1 
ATOM   2594 N  NE   C ARG A 1 168 ? -3.87661  -26.85902 23.09433 0.522 20.04015 ? 191 ARG A NE   1 
ATOM   2595 C  CZ   A ARG A 1 168 ? -1.97297  -26.32447 23.16592 0.478 19.38154 ? 191 ARG A CZ   1 
ATOM   2596 C  CZ   C ARG A 1 168 ? -3.41732  -28.05796 22.76241 0.522 23.75735 ? 191 ARG A CZ   1 
ATOM   2597 N  NH1  A ARG A 1 168 ? -2.79716  -27.26985 22.75675 0.478 20.16892 ? 191 ARG A NH1  1 
ATOM   2598 N  NH1  C ARG A 1 168 ? -2.22498  -28.21315 22.20196 0.522 19.68833 ? 191 ARG A NH1  1 
ATOM   2599 N  NH2  A ARG A 1 168 ? -0.66330  -26.47582 22.99048 0.478 21.04837 ? 191 ARG A NH2  1 
ATOM   2600 N  NH2  C ARG A 1 168 ? -4.17498  -29.12943 22.98980 0.522 27.54885 ? 191 ARG A NH2  1 
ATOM   2601 H  H    A ARG A 1 168 ? -3.49875  -20.67725 21.88613 0.478 19.54559 ? 191 ARG A H    1 
ATOM   2602 H  H    C ARG A 1 168 ? -3.51788  -20.68553 21.78906 0.522 19.57307 ? 191 ARG A H    1 
ATOM   2603 H  HA   A ARG A 1 168 ? -5.66132  -22.15038 21.96781 0.478 20.94339 ? 191 ARG A HA   1 
ATOM   2604 H  HA   C ARG A 1 168 ? -5.59064  -22.22335 21.93910 0.522 20.91657 ? 191 ARG A HA   1 
ATOM   2605 H  HB2  A ARG A 1 168 ? -3.64197  -23.06354 21.26137 0.478 20.69761 ? 191 ARG A HB2  1 
ATOM   2606 H  HB2  C ARG A 1 168 ? -3.54413  -23.14272 21.38394 0.522 20.73328 ? 191 ARG A HB2  1 
ATOM   2607 H  HB3  A ARG A 1 168 ? -3.05342  -22.90714 22.72921 0.478 20.69761 ? 191 ARG A HB3  1 
ATOM   2608 H  HB3  C ARG A 1 168 ? -2.98171  -22.82328 22.83551 0.522 20.73328 ? 191 ARG A HB3  1 
ATOM   2609 H  HG2  A ARG A 1 168 ? -5.36032  -24.39241 22.63894 0.478 21.16403 ? 191 ARG A HG2  1 
ATOM   2610 H  HG2  C ARG A 1 168 ? -4.53633  -24.34970 23.74402 0.522 21.42921 ? 191 ARG A HG2  1 
ATOM   2611 H  HG3  A ARG A 1 168 ? -4.13785  -25.07290 21.88532 0.478 21.16403 ? 191 ARG A HG3  1 
ATOM   2612 H  HG3  C ARG A 1 168 ? -5.02014  -24.70453 22.27248 0.522 21.42921 ? 191 ARG A HG3  1 
ATOM   2613 H  HD2  A ARG A 1 168 ? -3.93360  -24.20570 24.55952 0.478 24.16194 ? 191 ARG A HD2  1 
ATOM   2614 H  HD2  C ARG A 1 168 ? -2.86993  -25.65650 21.86055 0.522 18.26674 ? 191 ARG A HD2  1 
ATOM   2615 H  HD3  A ARG A 1 168 ? -4.30923  -25.70345 24.18395 0.478 24.16194 ? 191 ARG A HD3  1 
ATOM   2616 H  HD3  C ARG A 1 168 ? -2.52117  -25.42554 23.39367 0.522 18.26674 ? 191 ARG A HD3  1 
ATOM   2617 H  HE   A ARG A 1 168 ? -1.84881  -24.65709 24.03899 0.478 25.59882 ? 191 ARG A HE   1 
ATOM   2618 H  HE   C ARG A 1 168 ? -4.60959  -26.82528 23.54288 0.522 24.02809 ? 191 ARG A HE   1 
ATOM   2619 H  HH11 A ARG A 1 168 ? -3.64557  -27.17544 22.86111 0.478 24.18262 ? 191 ARG A HH11 1 
ATOM   2620 H  HH11 C ARG A 1 168 ? -1.73056  -27.52698 22.04602 0.522 23.60591 ? 191 ARG A HH11 1 
ATOM   2621 H  HH12 A ARG A 1 168 ? -2.48602  -27.98054 22.38565 0.478 24.18262 ? 191 ARG A HH12 1 
ATOM   2622 H  HH12 C ARG A 1 168 ? -1.94644  -28.99992 21.99458 0.522 23.60591 ? 191 ARG A HH12 1 
ATOM   2623 H  HH21 A ARG A 1 168 ? -0.12089  -25.86054 23.24900 0.478 25.23796 ? 191 ARG A HH21 1 
ATOM   2624 H  HH21 C ARG A 1 168 ? -4.95167  -29.03875 23.34775 0.522 33.03855 ? 191 ARG A HH21 1 
ATOM   2625 H  HH22 A ARG A 1 168 ? -0.35886  -27.18895 22.61852 0.478 25.23796 ? 191 ARG A HH22 1 
ATOM   2626 H  HH22 C ARG A 1 168 ? -3.88753  -29.91199 22.77868 0.522 33.03855 ? 191 ARG A HH22 1 
ATOM   2627 N  N    . ASN A 1 169 ? -4.42426  -21.40858 24.82531 1.000 17.92723 ? 192 ASN A N    1 
ATOM   2628 C  CA   . ASN A 1 169 ? -4.76874  -21.28503 26.23869 1.000 18.26294 ? 192 ASN A CA   1 
ATOM   2629 C  C    . ASN A 1 169 ? -6.02829  -20.46143 26.44737 1.000 14.89111 ? 192 ASN A C    1 
ATOM   2630 O  O    . ASN A 1 169 ? -6.89332  -20.82336 27.25050 1.000 18.64671 ? 192 ASN A O    1 
ATOM   2631 C  CB   . ASN A 1 169 ? -3.58139  -20.67177 26.94736 1.000 19.84436 ? 192 ASN A CB   1 
ATOM   2632 C  CG   . ASN A 1 169 ? -3.70139  -20.70885 28.43743 1.000 23.95611 ? 192 ASN A CG   1 
ATOM   2633 O  OD1  . ASN A 1 169 ? -4.54821  -21.40853 29.00649 1.000 29.14429 ? 192 ASN A OD1  1 
ATOM   2634 N  ND2  . ASN A 1 169 ? -2.82628  -19.94297 29.10340 1.000 26.97862 ? 192 ASN A ND2  1 
ATOM   2635 H  H    A ASN A 1 169 ? -3.65462  -21.08617 24.61720 0.478 21.49260 ? 192 ASN A H    1 
ATOM   2636 H  HA   . ASN A 1 169 ? -4.95378  -22.15870 26.61732 1.000 21.89545 ? 192 ASN A HA   1 
ATOM   2637 H  HB2  . ASN A 1 169 ? -2.78089  -21.16082 26.70050 1.000 23.79316 ? 192 ASN A HB2  1 
ATOM   2638 H  HB3  . ASN A 1 169 ? -3.49942  -19.74356 26.67791 1.000 23.79316 ? 192 ASN A HB3  1 
ATOM   2639 H  HD21 . ASN A 1 169 ? -2.84236  -19.91959 29.96293 1.000 32.35426 ? 192 ASN A HD21 1 
ATOM   2640 H  HD22 . ASN A 1 169 ? -2.24860  -19.47485 28.67125 1.000 32.35426 ? 192 ASN A HD22 1 
ATOM   2641 N  N    . LEU A 1 170 ? -6.17039  -19.37006 25.69487 1.000 17.20892 ? 193 LEU A N    1 
ATOM   2642 C  CA   . LEU A 1 170 ? -7.29521  -18.46964 25.89944 1.000 17.07517 ? 193 LEU A CA   1 
ATOM   2643 C  C    . LEU A 1 170 ? -8.61099  -19.06171 25.39136 1.000 17.44333 ? 193 LEU A C    1 
ATOM   2644 O  O    . LEU A 1 170 ? -9.65925  -18.89155 26.02105 1.000 16.42769 ? 193 LEU A O    1 
ATOM   2645 C  CB   . LEU A 1 170 ? -7.00399  -17.16005 25.19950 1.000 17.20281 ? 193 LEU A CB   1 
ATOM   2646 C  CG   . LEU A 1 170 ? -5.96819  -16.19510 25.77634 1.000 15.14051 ? 193 LEU A CG   1 
ATOM   2647 C  CD1  . LEU A 1 170 ? -5.76796  -15.05874 24.80699 1.000 19.71082 ? 193 LEU A CD1  1 
ATOM   2648 C  CD2  . LEU A 1 170 ? -6.43048  -15.73829 27.15538 1.000 20.16986 ? 193 LEU A CD2  1 
ATOM   2649 H  H    . LEU A 1 170 ? -5.63351  -19.13294 25.06627 1.000 20.63062 ? 193 LEU A H    1 
ATOM   2650 H  HA   . LEU A 1 170 ? -7.40197  -18.31162 26.85051 1.000 20.47013 ? 193 LEU A HA   1 
ATOM   2651 H  HB2  . LEU A 1 170 ? -6.70121  -17.37580 24.30358 1.000 20.62329 ? 193 LEU A HB2  1 
ATOM   2652 H  HB3  . LEU A 1 170 ? -7.83793  -16.66637 25.15798 1.000 20.62329 ? 193 LEU A HB3  1 
ATOM   2653 H  HG   . LEU A 1 170 ? -5.10284  -16.61623 25.89765 1.000 18.14853 ? 193 LEU A HG   1 
ATOM   2654 H  HD11 . LEU A 1 170 ? -5.12251  -14.43704 25.17818 1.000 23.63290 ? 193 LEU A HD11 1 
ATOM   2655 H  HD12 . LEU A 1 170 ? -5.43903  -15.41466 23.96674 1.000 23.63290 ? 193 LEU A HD12 1 
ATOM   2656 H  HD13 . LEU A 1 170 ? -6.61647  -14.61013 24.66667 1.000 23.63290 ? 193 LEU A HD13 1 
ATOM   2657 H  HD21 . LEU A 1 170 ? -5.81800  -15.06268 27.48601 1.000 24.18375 ? 193 LEU A HD21 1 
ATOM   2658 H  HD22 . LEU A 1 170 ? -7.32383  -15.36751 27.08220 1.000 24.18375 ? 193 LEU A HD22 1 
ATOM   2659 H  HD23 . LEU A 1 170 ? -6.43690  -16.50079 27.75492 1.000 24.18375 ? 193 LEU A HD23 1 
ATOM   2660 N  N    . THR A 1 171 ? -8.58928  -19.73081 24.24615 1.000 17.72883 ? 194 THR A N    1 
ATOM   2661 C  CA   . THR A 1 171 ? -9.84438  -20.14747 23.63191 1.000 20.90319 ? 194 THR A CA   1 
ATOM   2662 C  C    . THR A 1 171 ? -10.17873 -21.60142 23.86739 1.000 16.91442 ? 194 THR A C    1 
ATOM   2663 O  O    . THR A 1 171 ? -11.36565 -21.94776 23.86120 1.000 23.38985 ? 194 THR A O    1 
ATOM   2664 C  CB   . THR A 1 171 ? -9.81921  -19.94082 22.12501 1.000 15.24990 ? 194 THR A CB   1 
ATOM   2665 O  OG1  . THR A 1 171 ? -8.77991  -20.73708 21.54269 1.000 16.23978 ? 194 THR A OG1  1 
ATOM   2666 C  CG2  . THR A 1 171 ? -9.61892  -18.48698 21.79858 1.000 16.43475 ? 194 THR A CG2  1 
ATOM   2667 H  H    . THR A 1 171 ? -7.87824  -19.95055 23.81517 1.000 21.25452 ? 194 THR A H    1 
ATOM   2668 H  HA   . THR A 1 171 ? -10.54236 -19.59065 24.01096 1.000 25.06375 ? 194 THR A HA   1 
ATOM   2669 H  HB   . THR A 1 171 ? -10.66650 -20.21487 21.74044 1.000 18.27980 ? 194 THR A HB   1 
ATOM   2670 H  HG1  . THR A 1 171 ? -8.03567  -20.51843 21.86503 1.000 19.46765 ? 194 THR A HG1  1 
ATOM   2671 H  HG21 . THR A 1 171 ? -9.62294  -18.35924 20.83703 1.000 19.70162 ? 194 THR A HG21 1 
ATOM   2672 H  HG22 . THR A 1 171 ? -10.33184 -17.95793 22.18941 1.000 19.70162 ? 194 THR A HG22 1 
ATOM   2673 H  HG23 . THR A 1 171 ? -8.76938  -18.18132 22.15320 1.000 19.70162 ? 194 THR A HG23 1 
ATOM   2674 N  N    . LEU A 1 172 ? -9.16874  -22.46468 24.02187 1.000 17.71207 ? 195 LEU A N    1 
ATOM   2675 C  CA   . LEU A 1 172 ? -9.37117  -23.88639 24.24693 1.000 21.47160 ? 195 LEU A CA   1 
ATOM   2676 C  C    . LEU A 1 172 ? -8.90453  -24.37297 25.61760 1.000 20.47814 ? 195 LEU A C    1 
ATOM   2677 O  O    . LEU A 1 172 ? -9.34799  -25.44420 26.07350 1.000 21.01098 ? 195 LEU A O    1 
ATOM   2678 C  CB   . LEU A 1 172 ? -8.63775  -24.69270 23.16568 1.000 23.59386 ? 195 LEU A CB   1 
ATOM   2679 C  CG   . LEU A 1 172 ? -9.04465  -24.36265 21.72080 1.000 18.16685 ? 195 LEU A CG   1 
ATOM   2680 C  CD1  . LEU A 1 172 ? -8.17463  -25.17743 20.75892 1.000 20.46810 ? 195 LEU A CD1  1 
ATOM   2681 C  CD2  . LEU A 1 172 ? -10.53362 -24.66856 21.47756 1.000 24.28058 ? 195 LEU A CD2  1 
ATOM   2682 H  H    . LEU A 1 172 ? -8.33923  -22.23891 23.99868 1.000 21.23440 ? 195 LEU A H    1 
ATOM   2683 H  HA   . LEU A 1 172 ? -10.31979 -24.07787 24.18097 1.000 25.74584 ? 195 LEU A HA   1 
ATOM   2684 H  HB2  . LEU A 1 172 ? -7.68671  -24.52018 23.24726 1.000 28.29255 ? 195 LEU A HB2  1 
ATOM   2685 H  HB3  . LEU A 1 172 ? -8.81773  -25.63468 23.31119 1.000 28.29255 ? 195 LEU A HB3  1 
ATOM   2686 H  HG   . LEU A 1 172 ? -8.91296  -23.41565 21.55722 1.000 21.78014 ? 195 LEU A HG   1 
ATOM   2687 H  HD11 . LEU A 1 172 ? -8.48981  -25.03736 19.85231 1.000 24.54164 ? 195 LEU A HD11 1 
ATOM   2688 H  HD12 . LEU A 1 172 ? -7.25412  -24.88206 20.83844 1.000 24.54164 ? 195 LEU A HD12 1 
ATOM   2689 H  HD13 . LEU A 1 172 ? -8.24180  -26.11685 20.99104 1.000 24.54164 ? 195 LEU A HD13 1 
ATOM   2690 H  HD21 . LEU A 1 172 ? -10.74346 -24.49598 20.54639 1.000 29.11662 ? 195 LEU A HD21 1 
ATOM   2691 H  HD22 . LEU A 1 172 ? -10.70302 -25.60026 21.68764 1.000 29.11662 ? 195 LEU A HD22 1 
ATOM   2692 H  HD23 . LEU A 1 172 ? -11.07075 -24.09769 22.04897 1.000 29.11662 ? 195 LEU A HD23 1 
ATOM   2693 N  N    . GLY A 1 173 ? -7.99895  -23.64574 26.25198 1.000 21.91424 ? 196 GLY A N    1 
ATOM   2694 C  CA   . GLY A 1 173 ? -7.51151  -23.98091 27.57004 1.000 21.97626 ? 196 GLY A CA   1 
ATOM   2695 C  C    . GLY A 1 173 ? -8.28567  -23.24791 28.64330 1.000 24.17296 ? 196 GLY A C    1 
ATOM   2696 O  O    . GLY A 1 173 ? -9.42846  -22.82617 28.44925 1.000 20.71067 ? 196 GLY A O    1 
ATOM   2697 H  H    . GLY A 1 173 ? -7.64383  -22.93332 25.92648 1.000 26.27700 ? 196 GLY A H    1 
ATOM   2698 H  HA2  . GLY A 1 173 ? -7.60300  -24.93518 27.71800 1.000 26.35143 ? 196 GLY A HA2  1 
ATOM   2699 H  HA3  . GLY A 1 173 ? -6.57507  -23.73850 27.64216 1.000 26.35143 ? 196 GLY A HA3  1 
ATOM   2700 N  N    . LYS A 1 174 ? -7.62925  -23.07913 29.79727 1.000 22.91687 ? 197 LYS A N    1 
ATOM   2701 C  CA   . LYS A 1 174 ? -8.29208  -22.62335 31.00976 1.000 24.68941 ? 197 LYS A CA   1 
ATOM   2702 C  C    . LYS A 1 174 ? -7.71105  -21.31765 31.52457 1.000 23.71196 ? 197 LYS A C    1 
ATOM   2703 O  O    . LYS A 1 174 ? -7.84247  -21.00884 32.71603 1.000 24.88997 ? 197 LYS A O    1 
ATOM   2704 C  CB   . LYS A 1 174 ? -8.20023  -23.69484 32.08951 1.000 33.98489 ? 197 LYS A CB   1 
ATOM   2705 C  CG   . LYS A 1 174 ? -8.74323  -25.04903 31.64983 1.000 36.67308 ? 197 LYS A CG   1 
ATOM   2706 C  CD   . LYS A 1 174 ? -7.95237  -26.21063 32.27141 1.000 34.54355 ? 197 LYS A CD   1 
ATOM   2707 C  CE   . LYS A 1 174 ? -8.58359  -27.56186 31.93183 1.000 44.76691 ? 197 LYS A CE   1 
ATOM   2708 N  NZ   . LYS A 1 174 ? -8.49531  -27.92094 30.47882 1.000 50.95771 ? 197 LYS A NZ   1 
ATOM   2709 H  H    . LYS A 1 174 ? -6.78782  -23.22597 29.89744 1.000 27.48016 ? 197 LYS A H    1 
ATOM   2710 H  HA   . LYS A 1 174 ? -9.22811  -22.46765 30.80849 1.000 29.60722 ? 197 LYS A HA   1 
ATOM   2711 H  HB2  . LYS A 1 174 ? -7.26910  -23.81324 32.33421 1.000 40.76179 ? 197 LYS A HB2  1 
ATOM   2712 H  HB3  . LYS A 1 174 ? -8.71190  -23.40583 32.86124 1.000 40.76179 ? 197 LYS A HB3  1 
ATOM   2713 H  HG2  . LYS A 1 174 ? -9.66889  -25.12857 31.92865 1.000 43.98762 ? 197 LYS A HG2  1 
ATOM   2714 H  HG3  . LYS A 1 174 ? -8.68014  -25.12111 30.68457 1.000 43.98762 ? 197 LYS A HG3  1 
ATOM   2715 H  HD2  . LYS A 1 174 ? -7.04544  -26.20252 31.92745 1.000 41.43218 ? 197 LYS A HD2  1 
ATOM   2716 H  HD3  . LYS A 1 174 ? -7.94211  -26.11258 33.23639 1.000 41.43218 ? 197 LYS A HD3  1 
ATOM   2717 H  HE2  . LYS A 1 174 ? -8.12876  -28.25478 32.43570 1.000 53.70022 ? 197 LYS A HE2  1 
ATOM   2718 H  HE3  . LYS A 1 174 ? -9.52261  -27.53783 32.17384 1.000 53.70022 ? 197 LYS A HE3  1 
ATOM   2719 H  HZ1  . LYS A 1 174 ? -8.89196  -27.29498 29.98592 1.000 61.12917 ? 197 LYS A HZ1  1 
ATOM   2720 H  HZ2  . LYS A 1 174 ? -7.64252  -27.98525 30.23242 1.000 61.12917 ? 197 LYS A HZ2  1 
ATOM   2721 H  HZ3  . LYS A 1 174 ? -8.89770  -28.70130 30.33312 1.000 61.12917 ? 197 LYS A HZ3  1 
ATOM   2722 N  N    . ALA A 1 175 ? -7.07221  -20.54448 30.65142 1.000 24.66392 ? 198 ALA A N    1 
ATOM   2723 C  CA   . ALA A 1 175 ? -6.62165  -19.21556 31.05156 1.000 22.37903 ? 198 ALA A CA   1 
ATOM   2724 C  C    . ALA A 1 175 ? -7.74965  -18.38520 31.66402 1.000 21.33795 ? 198 ALA A C    1 
ATOM   2725 O  O    . ALA A 1 175 ? -7.53247  -17.63729 32.62271 1.000 21.63752 ? 198 ALA A O    1 
ATOM   2726 C  CB   . ALA A 1 175 ? -6.04886  -18.49444 29.83942 1.000 18.71986 ? 198 ALA A CB   1 
ATOM   2727 H  H    . ALA A 1 175 ? -6.89068  -20.76010 29.83892 1.000 29.57662 ? 198 ALA A H    1 
ATOM   2728 H  HA   . ALA A 1 175 ? -5.92978  -19.31346 31.72435 1.000 26.83476 ? 198 ALA A HA   1 
ATOM   2729 H  HB1  . ALA A 1 175 ? -5.86287  -17.57304 30.07885 1.000 22.44375 ? 198 ALA A HB1  1 
ATOM   2730 H  HB2  . ALA A 1 175 ? -5.23001  -18.93702 29.56646 1.000 22.44375 ? 198 ALA A HB2  1 
ATOM   2731 H  HB3  . ALA A 1 175 ? -6.69722  -18.52447 29.11857 1.000 22.44375 ? 198 ALA A HB3  1 
ATOM   2732 N  N    . LEU A 1 176 ? -8.94277  -18.47365 31.08750 1.000 17.41040 ? 199 LEU A N    1 
ATOM   2733 C  CA   . LEU A 1 176 ? -10.12305 -17.71945 31.47930 1.000 18.18376 ? 199 LEU A CA   1 
ATOM   2734 C  C    . LEU A 1 176 ? -11.15843 -18.64430 32.10144 1.000 19.33397 ? 199 LEU A C    1 
ATOM   2735 O  O    . LEU A 1 176 ? -11.19270 -19.84702 31.81705 1.000 19.50351 ? 199 LEU A O    1 
ATOM   2736 C  CB   . LEU A 1 176 ? -10.72538 -17.01276 30.25269 1.000 17.66196 ? 199 LEU A CB   1 
ATOM   2737 C  CG   . LEU A 1 176 ? -9.83536  -15.96966 29.56620 1.000 17.22308 ? 199 LEU A CG   1 
ATOM   2738 C  CD1  . LEU A 1 176 ? -10.53885 -15.43940 28.34072 1.000 18.08070 ? 199 LEU A CD1  1 
ATOM   2739 C  CD2  . LEU A 1 176 ? -9.53218  -14.86618 30.55952 1.000 20.08588 ? 199 LEU A CD2  1 
ATOM   2740 H  H    . LEU A 1 176 ? -9.10186  -18.99805 30.42471 1.000 20.87239 ? 199 LEU A H    1 
ATOM   2741 H  HA   . LEU A 1 176 ? -9.88635  -17.05303 32.14319 1.000 21.80043 ? 199 LEU A HA   1 
ATOM   2742 H  HB2  . LEU A 1 176 ? -10.93798 -17.68828 29.58983 1.000 21.17427 ? 199 LEU A HB2  1 
ATOM   2743 H  HB3  . LEU A 1 176 ? -11.53455 -16.55782 30.53407 1.000 21.17427 ? 199 LEU A HB3  1 
ATOM   2744 H  HG   . LEU A 1 176 ? -8.99500  -16.35653 29.27460 1.000 20.64761 ? 199 LEU A HG   1 
ATOM   2745 H  HD11 . LEU A 1 176 ? -9.96475  -14.79197 27.90237 1.000 21.67676 ? 199 LEU A HD11 1 
ATOM   2746 H  HD12 . LEU A 1 176 ? -10.72482 -16.17732 27.73924 1.000 21.67676 ? 199 LEU A HD12 1 
ATOM   2747 H  HD13 . LEU A 1 176 ? -11.36858 -15.01603 28.61129 1.000 21.67676 ? 199 LEU A HD13 1 
ATOM   2748 H  HD21 . LEU A 1 176 ? -9.08397  -14.14022 30.09801 1.000 24.08297 ? 199 LEU A HD21 1 
ATOM   2749 H  HD22 . LEU A 1 176 ? -10.36467 -14.54980 30.94391 1.000 24.08297 ? 199 LEU A HD22 1 
ATOM   2750 H  HD23 . LEU A 1 176 ? -8.95834  -15.21861 31.25766 1.000 24.08297 ? 199 LEU A HD23 1 
ATOM   2751 N  N    . GLY A 1 177 ? -11.95619 -18.09817 33.01342 1.000 21.94723 ? 200 GLY A N    1 
ATOM   2752 C  CA   . GLY A 1 177 ? -13.08322 -18.85476 33.53070 1.000 24.55773 ? 200 GLY A CA   1 
ATOM   2753 C  C    . GLY A 1 177 ? -14.01642 -19.28894 32.41454 1.000 21.87098 ? 200 GLY A C    1 
ATOM   2754 O  O    . GLY A 1 177 ? -14.01531 -18.73792 31.32517 1.000 22.58774 ? 200 GLY A O    1 
ATOM   2755 H  H    . GLY A 1 177 ? -11.86692 -17.30800 33.34094 1.000 26.31659 ? 200 GLY A H    1 
ATOM   2756 H  HA2  . GLY A 1 177 ? -12.76043 -19.64567 33.99024 1.000 29.44919 ? 200 GLY A HA2  1 
ATOM   2757 H  HA3  . GLY A 1 177 ? -13.58238 -18.30735 34.15687 1.000 29.44919 ? 200 GLY A HA3  1 
ATOM   2758 N  N    . ASP A 1 178 ? -14.85515 -20.27416 32.72230 1.000 27.71451 ? 201 ASP A N    1 
ATOM   2759 C  CA   . ASP A 1 178 ? -15.71023 -20.85836 31.69368 1.000 29.09495 ? 201 ASP A CA   1 
ATOM   2760 C  C    . ASP A 1 178 ? -16.60150 -19.80162 31.04298 1.000 23.03938 ? 201 ASP A C    1 
ATOM   2761 O  O    . ASP A 1 178 ? -16.72223 -19.74705 29.81375 1.000 24.20941 ? 201 ASP A O    1 
ATOM   2762 C  CB   . ASP A 1 178 ? -16.54780 -21.98779 32.29328 1.000 29.45598 ? 201 ASP A CB   1 
ATOM   2763 C  CG   . ASP A 1 178 ? -15.82501 -23.32667 32.27141 1.000 36.21494 ? 201 ASP A CG   1 
ATOM   2764 O  OD1  . ASP A 1 178 ? -14.62492 -23.37914 31.90028 1.000 34.28991 ? 201 ASP A OD1  1 
ATOM   2765 O  OD2  . ASP A 1 178 ? -16.47072 -24.32849 32.58725 1.000 33.99990 ? 201 ASP A OD2  1 
ATOM   2766 H  H    . ASP A 1 178 ? -14.94753 -20.61725 33.50547 1.000 33.23733 ? 201 ASP A H    1 
ATOM   2767 H  HA   . ASP A 1 178 ? -15.14897 -21.23651 30.99877 1.000 34.89385 ? 201 ASP A HA   1 
ATOM   2768 H  HB2  . ASP A 1 178 ? -16.75481 -21.77295 33.21626 1.000 35.32710 ? 201 ASP A HB2  1 
ATOM   2769 H  HB3  . ASP A 1 178 ? -17.36715 -22.08010 31.78235 1.000 35.32710 ? 201 ASP A HB3  1 
ATOM   2770 N  N    . SER A 1 179 ? -17.23119 -18.93924 31.84403 1.000 23.14065 ? 202 SER A N    1 
ATOM   2771 C  CA   . SER A 1 179 ? -18.07550 -17.90005 31.23870 1.000 22.05791 ? 202 SER A CA   1 
ATOM   2772 C  C    . SER A 1 179 ? -17.26147 -16.98903 30.33285 1.000 22.15652 ? 202 SER A C    1 
ATOM   2773 O  O    . SER A 1 179 ? -17.68540 -16.63785 29.21767 1.000 21.08345 ? 202 SER A O    1 
ATOM   2774 C  CB   . SER A 1 179 ? -18.76776 -17.10313 32.34725 1.000 25.99413 ? 202 SER A CB   1 
ATOM   2775 O  OG   . SER A 1 179 ? -19.59237 -16.07440 31.82648 1.000 29.59556 ? 202 SER A OG   1 
ATOM   2776 H  H    . SER A 1 179 ? -17.19023 -18.93180 32.70302 1.000 27.74870 ? 202 SER A H    1 
ATOM   2777 H  HA   . SER A 1 179 ? -18.76054 -18.31511 30.69158 1.000 26.44941 ? 202 SER A HA   1 
ATOM   2778 H  HB2  . SER A 1 179 ? -19.31768 -17.70862 32.86865 1.000 31.17288 ? 202 SER A HB2  1 
ATOM   2779 H  HB3  . SER A 1 179 ? -18.08898 -16.70173 32.91210 1.000 31.17288 ? 202 SER A HB3  1 
ATOM   2780 H  HG   . SER A 1 179 ? -19.11782 -15.46861 31.48969 1.000 35.49459 ? 202 SER A HG   1 
ATOM   2781 N  N    . GLN A 1 180 ? -16.06935 -16.62658 30.78434 1.000 23.49483 ? 203 GLN A N    1 
ATOM   2782 C  CA   . GLN A 1 180 ? -15.25863 -15.65690 30.06934 1.000 20.46024 ? 203 GLN A CA   1 
ATOM   2783 C  C    . GLN A 1 180 ? -14.65757 -16.25992 28.81486 1.000 20.66752 ? 203 GLN A C    1 
ATOM   2784 O  O    . GLN A 1 180 ? -14.55545 -15.58108 27.77086 1.000 17.56779 ? 203 GLN A O    1 
ATOM   2785 C  CB   . GLN A 1 180 ? -14.17058 -15.12921 31.01109 1.000 17.06848 ? 203 GLN A CB   1 
ATOM   2786 C  CG   . GLN A 1 180 ? -14.66795 -14.26077 32.16543 1.000 19.80575 ? 203 GLN A CG   1 
ATOM   2787 C  CD   . GLN A 1 180 ? -15.32344 -15.04622 33.26274 1.000 24.17266 ? 203 GLN A CD   1 
ATOM   2788 O  OE1  . GLN A 1 180 ? -15.08439 -16.24947 33.41823 1.000 25.03969 ? 203 GLN A OE1  1 
ATOM   2789 N  NE2  . GLN A 1 180 ? -16.13907 -14.36634 34.06484 1.000 29.60273 ? 203 GLN A NE2  1 
ATOM   2790 H  H    . GLN A 1 180 ? -15.70627 -16.92771 31.50343 1.000 28.17371 ? 203 GLN A H    1 
ATOM   2791 H  HA   . GLN A 1 180 ? -15.80983 -14.90912 29.79023 1.000 24.53220 ? 203 GLN A HA   1 
ATOM   2792 H  HB2  . GLN A 1 180 ? -13.70786 -15.88839 31.39896 1.000 20.46210 ? 203 GLN A HB2  1 
ATOM   2793 H  HB3  . GLN A 1 180 ? -13.55106 -14.59296 30.49193 1.000 20.46210 ? 203 GLN A HB3  1 
ATOM   2794 H  HG2  . GLN A 1 180 ? -13.91350 -13.78690 32.54903 1.000 23.74682 ? 203 GLN A HG2  1 
ATOM   2795 H  HG3  . GLN A 1 180 ? -15.31851 -13.62757 31.82378 1.000 23.74682 ? 203 GLN A HG3  1 
ATOM   2796 H  HE21 . GLN A 1 180 ? -16.26443 -13.52508 33.93769 1.000 35.50320 ? 203 GLN A HE21 1 
ATOM   2797 H  HE22 . GLN A 1 180 ? -16.54082 -14.76822 34.71035 1.000 35.50320 ? 203 GLN A HE22 1 
ATOM   2798 N  N    . ARG A 1 181 ? -14.23960 -17.52601 28.89311 1.000 20.45098 ? 204 ARG A N    1 
ATOM   2799 C  CA   A ARG A 1 181 ? -13.71941 -18.20466 27.70949 0.635 20.28180 ? 204 ARG A CA   1 
ATOM   2800 C  CA   B ARG A 1 181 ? -13.72015 -18.20307 27.70930 0.365 20.30694 ? 204 ARG A CA   1 
ATOM   2801 C  C    . ARG A 1 181 ? -14.79486 -18.31121 26.63680 1.000 21.06574 ? 204 ARG A C    1 
ATOM   2802 O  O    . ARG A 1 181 ? -14.55291 -18.01430 25.45444 1.000 21.27536 ? 204 ARG A O    1 
ATOM   2803 C  CB   A ARG A 1 181 ? -13.20299 -19.59838 28.07227 0.635 19.64534 ? 204 ARG A CB   1 
ATOM   2804 C  CB   B ARG A 1 181 ? -13.20004 -19.58941 28.08840 0.365 19.77428 ? 204 ARG A CB   1 
ATOM   2805 C  CG   A ARG A 1 181 ? -12.80419 -20.41478 26.86103 0.635 26.78165 ? 204 ARG A CG   1 
ATOM   2806 C  CG   B ARG A 1 181 ? -12.77220 -20.42685 26.91083 0.365 26.70056 ? 204 ARG A CG   1 
ATOM   2807 C  CD   A ARG A 1 181 ? -12.33019 -21.79108 27.25952 0.635 24.96718 ? 204 ARG A CD   1 
ATOM   2808 C  CD   B ARG A 1 181 ? -12.09017 -21.69517 27.37939 0.365 25.33484 ? 204 ARG A CD   1 
ATOM   2809 N  NE   A ARG A 1 181 ? -13.41647 -22.65718 27.70996 0.635 27.80678 ? 204 ARG A NE   1 
ATOM   2810 N  NE   B ARG A 1 181 ? -12.98903 -22.60188 28.08917 0.365 29.71826 ? 204 ARG A NE   1 
ATOM   2811 C  CZ   A ARG A 1 181 ? -13.25254 -23.91696 28.08973 0.635 29.33644 ? 204 ARG A CZ   1 
ATOM   2812 C  CZ   B ARG A 1 181 ? -12.97987 -22.81092 29.40077 0.365 29.16054 ? 204 ARG A CZ   1 
ATOM   2813 N  NH1  A ARG A 1 181 ? -12.05048 -24.47318 28.14500 0.635 38.10257 ? 204 ARG A NH1  1 
ATOM   2814 N  NH1  B ARG A 1 181 ? -12.16064 -22.15086 30.20482 0.365 24.64134 ? 204 ARG A NH1  1 
ATOM   2815 N  NH2  A ARG A 1 181 ? -14.32075 -24.64023 28.42126 0.635 37.65615 ? 204 ARG A NH2  1 
ATOM   2816 N  NH2  B ARG A 1 181 ? -13.81138 -23.71244 29.91875 0.365 33.14864 ? 204 ARG A NH2  1 
ATOM   2817 H  H    A ARG A 1 181 ? -14.24717 -18.00449 29.60768 0.635 24.52109 ? 204 ARG A H    1 
ATOM   2818 H  H    B ARG A 1 181 ? -14.24691 -18.00473 29.60752 0.365 24.52109 ? 204 ARG A H    1 
ATOM   2819 H  HA   A ARG A 1 181 ? -12.97457 -17.68968 27.36176 0.635 24.31808 ? 204 ARG A HA   1 
ATOM   2820 H  HA   B ARG A 1 181 ? -12.97907 -17.69042 27.35030 0.365 24.34824 ? 204 ARG A HA   1 
ATOM   2821 H  HB2  A ARG A 1 181 ? -12.42304 -19.50675 28.64164 0.635 23.55432 ? 204 ARG A HB2  1 
ATOM   2822 H  HB2  B ARG A 1 181 ? -12.43138 -19.48449 28.67069 0.365 23.70906 ? 204 ARG A HB2  1 
ATOM   2823 H  HB3  A ARG A 1 181 ? -13.90157 -20.08063 28.54165 0.635 23.55432 ? 204 ARG A HB3  1 
ATOM   2824 H  HB3  B ARG A 1 181 ? -13.90412 -20.06956 28.55168 0.365 23.70906 ? 204 ARG A HB3  1 
ATOM   2825 H  HG2  A ARG A 1 181 ? -13.56926 -20.51332 26.27293 0.635 32.11790 ? 204 ARG A HG2  1 
ATOM   2826 H  HG2  B ARG A 1 181 ? -13.55052 -20.67073 26.38582 0.365 32.02059 ? 204 ARG A HG2  1 
ATOM   2827 H  HG3  A ARG A 1 181 ? -12.08217 -19.96618 26.39376 0.635 32.11790 ? 204 ARG A HG3  1 
ATOM   2828 H  HG3  B ARG A 1 181 ? -12.14776 -19.92425 26.36460 0.365 32.02059 ? 204 ARG A HG3  1 
ATOM   2829 H  HD2  A ARG A 1 181 ? -11.90810 -22.21339 26.49506 0.635 29.94053 ? 204 ARG A HD2  1 
ATOM   2830 H  HD2  B ARG A 1 181 ? -11.73878 -22.16699 26.60815 0.365 30.38173 ? 204 ARG A HD2  1 
ATOM   2831 H  HD3  A ARG A 1 181 ? -11.69307 -21.70761 27.98616 0.635 29.94053 ? 204 ARG A HD3  1 
ATOM   2832 H  HD3  B ARG A 1 181 ? -11.36739 -21.45976 27.98194 0.365 30.38173 ? 204 ARG A HD3  1 
ATOM   2833 H  HE   A ARG A 1 181 ? -14.21151 -22.32990 27.73013 0.635 33.34806 ? 204 ARG A HE   1 
ATOM   2834 H  HE   B ARG A 1 181 ? -13.56827 -23.03319 27.62220 0.365 35.64183 ? 204 ARG A HE   1 
ATOM   2835 H  HH11 A ARG A 1 181 ? -11.35452 -24.01517 27.93175 0.635 45.70301 ? 204 ARG A HH11 1 
ATOM   2836 H  HH11 B ARG A 1 181 ? -11.61605 -21.56945 29.88079 0.365 29.54952 ? 204 ARG A HH11 1 
ATOM   2837 H  HH12 A ARG A 1 181 ? -11.96662 -25.29203 28.39411 0.635 45.70301 ? 204 ARG A HH12 1 
ATOM   2838 H  HH12 B ARG A 1 181 ? -12.17314 -22.30357 31.05106 0.365 29.54952 ? 204 ARG A HH12 1 
ATOM   2839 H  HH21 A ARG A 1 181 ? -15.10510 -24.28915 28.38755 0.635 45.16730 ? 204 ARG A HH21 1 
ATOM   2840 H  HH21 B ARG A 1 181 ? -14.34484 -24.15027 29.40559 0.365 39.75828 ? 204 ARG A HH21 1 
ATOM   2841 H  HH22 A ARG A 1 181 ? -14.22611 -25.45831 28.66903 0.635 45.16730 ? 204 ARG A HH22 1 
ATOM   2842 H  HH22 B ARG A 1 181 ? -13.81506 -23.85697 30.76651 0.365 39.75828 ? 204 ARG A HH22 1 
ATOM   2843 N  N    . ALA A 1 182 ? -15.98401 -18.72988 27.03233 1.000 18.96678 ? 205 ALA A N    1 
ATOM   2844 C  CA   . ALA A 1 182 ? -17.08875 -18.81461 26.09281 1.000 20.59140 ? 205 ALA A CA   1 
ATOM   2845 C  C    . ALA A 1 182 ? -17.34324 -17.45485 25.47231 1.000 21.27845 ? 205 ALA A C    1 
ATOM   2846 O  O    . ALA A 1 182 ? -17.63029 -17.35560 24.28173 1.000 22.53837 ? 205 ALA A O    1 
ATOM   2847 C  CB   . ALA A 1 182 ? -18.34127 -19.34360 26.80032 1.000 23.70899 ? 205 ALA A CB   1 
ATOM   2848 H  H    . ALA A 1 182 ? -16.17891 -18.97019 27.83475 1.000 22.74005 ? 205 ALA A H    1 
ATOM   2849 H  HA   . ALA A 1 182 ? -16.87353 -19.44174 25.38479 1.000 24.68960 ? 205 ALA A HA   1 
ATOM   2850 H  HB1  . ALA A 1 182 ? -19.06829 -19.39346 26.16012 1.000 28.43070 ? 205 ALA A HB1  1 
ATOM   2851 H  HB2  . ALA A 1 182 ? -18.15358 -20.22588 27.15706 1.000 28.43070 ? 205 ALA A HB2  1 
ATOM   2852 H  HB3  . ALA A 1 182 ? -18.57615 -18.73846 27.52110 1.000 28.43070 ? 205 ALA A HB3  1 
ATOM   2853 N  N    . GLN A 1 183 ? -17.26986 -16.38986 26.27284 1.000 19.56419 ? 206 GLN A N    1 
ATOM   2854 C  CA   . GLN A 1 183 ? -17.54226 -15.05920 25.74149 1.000 18.84586 ? 206 GLN A CA   1 
ATOM   2855 C  C    . GLN A 1 183 ? -16.49877 -14.66505 24.71215 1.000 16.74498 ? 206 GLN A C    1 
ATOM   2856 O  O    . GLN A 1 183 ? -16.83273 -14.11635 23.64775 1.000 16.70846 ? 206 GLN A O    1 
ATOM   2857 C  CB   . GLN A 1 183 ? -17.58900 -14.03833 26.88749 1.000 21.55867 ? 206 GLN A CB   1 
ATOM   2858 C  CG   . GLN A 1 183 ? -17.87852 -12.62673 26.42258 1.000 16.47287 ? 206 GLN A CG   1 
ATOM   2859 C  CD   . GLN A 1 183 ? -19.25876 -12.49431 25.83771 1.000 21.05790 ? 206 GLN A CD   1 
ATOM   2860 O  OE1  . GLN A 1 183 ? -20.23304 -12.29668 26.55031 1.000 25.47901 ? 206 GLN A OE1  1 
ATOM   2861 N  NE2  . GLN A 1 183 ? -19.35277 -12.65475 24.52012 1.000 21.98884 ? 206 GLN A NE2  1 
ATOM   2862 H  H    . GLN A 1 183 ? -17.06874 -16.41187 27.10870 1.000 23.45695 ? 206 GLN A H    1 
ATOM   2863 H  HA   . GLN A 1 183 ? -18.40960 -15.05963 25.30717 1.000 22.59495 ? 206 GLN A HA   1 
ATOM   2864 H  HB2  . GLN A 1 183 ? -18.28776 -14.29649 27.50878 1.000 25.85032 ? 206 GLN A HB2  1 
ATOM   2865 H  HB3  . GLN A 1 183 ? -16.72990 -14.03328 27.33785 1.000 25.85032 ? 206 GLN A HB3  1 
ATOM   2866 H  HG2  . GLN A 1 183 ? -17.81084 -12.02234 27.17825 1.000 19.74736 ? 206 GLN A HG2  1 
ATOM   2867 H  HG3  . GLN A 1 183 ? -17.23558 -12.37798 25.74019 1.000 19.74736 ? 206 GLN A HG3  1 
ATOM   2868 H  HE21 . GLN A 1 183 ? -18.64858 -12.82341 24.05615 1.000 26.36653 ? 206 GLN A HE21 1 
ATOM   2869 H  HE22 . GLN A 1 183 ? -20.11772 -12.58978 24.13253 1.000 26.36653 ? 206 GLN A HE22 1 
ATOM   2870 N  N    . LEU A 1 184 ? -15.22858 -14.92541 25.00357 1.000 17.20708 ? 207 LEU A N    1 
ATOM   2871 C  CA   . LEU A 1 184 ? -14.17599 -14.58785 24.04466 1.000 19.76495 ? 207 LEU A CA   1 
ATOM   2872 C  C    . LEU A 1 184 ? -14.40527 -15.31208 22.73061 1.000 19.57776 ? 207 LEU A C    1 
ATOM   2873 O  O    . LEU A 1 184 ? -14.32568 -14.71833 21.64483 1.000 17.94851 ? 207 LEU A O    1 
ATOM   2874 C  CB   . LEU A 1 184 ? -12.81088 -14.94154 24.61906 1.000 15.55620 ? 207 LEU A CB   1 
ATOM   2875 C  CG   . LEU A 1 184 ? -11.60037 -14.79940 23.67643 1.000 14.45371 ? 207 LEU A CG   1 
ATOM   2876 C  CD1  . LEU A 1 184 ? -11.47243 -13.36159 23.24924 1.000 18.87895 ? 207 LEU A CD1  1 
ATOM   2877 C  CD2  . LEU A 1 184 ? -10.28154 -15.21166 24.35998 1.000 19.21710 ? 207 LEU A CD2  1 
ATOM   2878 H  H    . LEU A 1 184 ? -14.95239 -15.28878 25.73246 1.000 20.62842 ? 207 LEU A H    1 
ATOM   2879 H  HA   . LEU A 1 184 ? -14.19071 -13.63217 23.87927 1.000 23.69786 ? 207 LEU A HA   1 
ATOM   2880 H  HB2  . LEU A 1 184 ? -12.64736 -14.36215 25.37963 1.000 18.64736 ? 207 LEU A HB2  1 
ATOM   2881 H  HB3  . LEU A 1 184 ? -12.83854 -15.86736 24.90716 1.000 18.64736 ? 207 LEU A HB3  1 
ATOM   2882 H  HG   . LEU A 1 184 ? -11.74429 -15.38200 22.91435 1.000 17.32438 ? 207 LEU A HG   1 
ATOM   2883 H  HD11 . LEU A 1 184 ? -10.68908 -13.26835 22.68481 1.000 22.63466 ? 207 LEU A HD11 1 
ATOM   2884 H  HD12 . LEU A 1 184 ? -12.26779 -13.10674 22.75594 1.000 22.63466 ? 207 LEU A HD12 1 
ATOM   2885 H  HD13 . LEU A 1 184 ? -11.37989 -12.80480 24.03811 1.000 22.63466 ? 207 LEU A HD13 1 
ATOM   2886 H  HD21 . LEU A 1 184 ? -9.55539  -15.12654 23.72251 1.000 23.04044 ? 207 LEU A HD21 1 
ATOM   2887 H  HD22 . LEU A 1 184 ? -10.12441 -14.62977 25.11998 1.000 23.04044 ? 207 LEU A HD22 1 
ATOM   2888 H  HD23 . LEU A 1 184 ? -10.35431 -16.13203 24.65752 1.000 23.04044 ? 207 LEU A HD23 1 
ATOM   2889 N  N    . VAL A 1 185 ? -14.71973 -16.59984 22.80929 1.000 16.03690 ? 208 VAL A N    1 
ATOM   2890 C  CA   . VAL A 1 185 ? -14.88560 -17.40775 21.60514 1.000 17.88377 ? 208 VAL A CA   1 
ATOM   2891 C  C    . VAL A 1 185 ? -16.11905 -16.96097 20.83704 1.000 17.61053 ? 208 VAL A C    1 
ATOM   2892 O  O    . VAL A 1 185 ? -16.08958 -16.81026 19.61349 1.000 21.92167 ? 208 VAL A O    1 
ATOM   2893 C  CB   . VAL A 1 185 ? -14.93789 -18.89364 22.00597 1.000 24.42752 ? 208 VAL A CB   1 
ATOM   2894 C  CG1  . VAL A 1 185 ? -15.29610 -19.77649 20.82514 1.000 30.97554 ? 208 VAL A CG1  1 
ATOM   2895 C  CG2  . VAL A 1 185 ? -13.58593 -19.29133 22.60832 1.000 22.71489 ? 208 VAL A CG2  1 
ATOM   2896 H  H    . VAL A 1 185 ? -14.84253 -17.03003 23.54377 1.000 19.22421 ? 208 VAL A H    1 
ATOM   2897 H  HA   . VAL A 1 185 ? -14.12732 -17.28236 21.01338 1.000 21.44044 ? 208 VAL A HA   1 
ATOM   2898 H  HB   . VAL A 1 185 ? -15.63393 -19.02682 22.66830 1.000 29.29294 ? 208 VAL A HB   1 
ATOM   2899 H  HG11 . VAL A 1 185 ? -15.07575 -20.69632 21.04023 1.000 37.15057 ? 208 VAL A HG11 1 
ATOM   2900 H  HG12 . VAL A 1 185 ? -16.24645 -19.69674 20.64803 1.000 37.15057 ? 208 VAL A HG12 1 
ATOM   2901 H  HG13 . VAL A 1 185 ? -14.78976 -19.48767 20.04983 1.000 37.15057 ? 208 VAL A HG13 1 
ATOM   2902 H  HG21 . VAL A 1 185 ? -13.62130 -20.22297 22.87609 1.000 27.23779 ? 208 VAL A HG21 1 
ATOM   2903 H  HG22 . VAL A 1 185 ? -12.89344 -19.16504 21.94094 1.000 27.23779 ? 208 VAL A HG22 1 
ATOM   2904 H  HG23 . VAL A 1 185 ? -13.40731 -18.73184 23.38031 1.000 27.23779 ? 208 VAL A HG23 1 
ATOM   2905 N  N    . THR A 1 186 ? -17.21046 -16.68393 21.54497 1.000 19.86255 ? 209 THR A N    1 
ATOM   2906 C  CA   . THR A 1 186 ? -18.38834 -16.13924 20.87850 1.000 21.93884 ? 209 THR A CA   1 
ATOM   2907 C  C    . THR A 1 186 ? -18.07551 -14.82814 20.16560 1.000 21.96712 ? 209 THR A C    1 
ATOM   2908 O  O    . THR A 1 186 ? -18.51575 -14.60470 19.03812 1.000 19.22777 ? 209 THR A O    1 
ATOM   2909 C  CB   . THR A 1 186 ? -19.49100 -15.95090 21.90986 1.000 21.95698 ? 209 THR A CB   1 
ATOM   2910 O  OG1  . THR A 1 186 ? -19.88895 -17.24295 22.39462 1.000 28.85514 ? 209 THR A OG1  1 
ATOM   2911 C  CG2  . THR A 1 186 ? -20.70262 -15.17904 21.29720 1.000 21.08869 ? 209 THR A CG2  1 
ATOM   2912 H  H    . THR A 1 186 ? -17.29366 -16.79922 22.39314 1.000 23.81498 ? 209 THR A H    1 
ATOM   2913 H  HA   . THR A 1 186 ? -18.69640 -16.76273 20.20230 1.000 26.30653 ? 209 THR A HA   1 
ATOM   2914 H  HB   . THR A 1 186 ? -19.17329 -15.41713 22.65488 1.000 26.32830 ? 209 THR A HB   1 
ATOM   2915 H  HG1  . THR A 1 186 ? -20.47218 -17.15811 22.99316 1.000 34.60608 ? 209 THR A HG1  1 
ATOM   2916 H  HG21 . THR A 1 186 ? -21.48398 -15.28605 21.86193 1.000 25.28635 ? 209 THR A HG21 1 
ATOM   2917 H  HG22 . THR A 1 186 ? -20.49264 -14.23473 21.22595 1.000 25.28635 ? 209 THR A HG22 1 
ATOM   2918 H  HG23 . THR A 1 186 ? -20.90335 -15.52446 20.41330 1.000 25.28635 ? 209 THR A HG23 1 
ATOM   2919 N  N    . TRP A 1 187 ? -17.33650 -13.93415 20.81379 1.000 17.93203 ? 210 TRP A N    1 
ATOM   2920 C  CA   . TRP A 1 187 ? -16.96383 -12.68249 20.15633 1.000 21.21560 ? 210 TRP A CA   1 
ATOM   2921 C  C    . TRP A 1 187 ? -16.13328 -12.92718 18.89855 1.000 20.50512 ? 210 TRP A C    1 
ATOM   2922 O  O    . TRP A 1 187 ? -16.39658 -12.33321 17.83539 1.000 17.76430 ? 210 TRP A O    1 
ATOM   2923 C  CB   . TRP A 1 187 ? -16.20808 -11.80577 21.15068 1.000 19.50730 ? 210 TRP A CB   1 
ATOM   2924 C  CG   . TRP A 1 187 ? -17.10426 -11.01272 22.10848 1.000 18.45938 ? 210 TRP A CG   1 
ATOM   2925 C  CD1  . TRP A 1 187 ? -18.38539 -10.60982 21.89800 1.000 21.65111 ? 210 TRP A CD1  1 
ATOM   2926 C  CD2  . TRP A 1 187 ? -16.73080 -10.53275 23.40492 1.000 16.05373 ? 210 TRP A CD2  1 
ATOM   2927 N  NE1  . TRP A 1 187 ? -18.84276 -9.90310  22.99932 1.000 22.10236 ? 210 TRP A NE1  1 
ATOM   2928 C  CE2  . TRP A 1 187 ? -17.84181 -9.84518  23.93240 1.000 18.28847 ? 210 TRP A CE2  1 
ATOM   2929 C  CE3  . TRP A 1 187 ? -15.55635 -10.61615 24.16817 1.000 21.80423 ? 210 TRP A CE3  1 
ATOM   2930 C  CZ2  . TRP A 1 187 ? -17.81062 -9.23328  25.17759 1.000 22.26199 ? 210 TRP A CZ2  1 
ATOM   2931 C  CZ3  . TRP A 1 187 ? -15.54176 -10.03279 25.41768 1.000 22.02855 ? 210 TRP A CZ3  1 
ATOM   2932 C  CH2  . TRP A 1 187 ? -16.65280 -9.34031  25.90012 1.000 18.28078 ? 210 TRP A CH2  1 
ATOM   2933 H  H    . TRP A 1 187 ? -17.04305 -14.02343 21.61723 1.000 21.49836 ? 210 TRP A H    1 
ATOM   2934 H  HA   . TRP A 1 187 ? -17.76832 -12.21768 19.87767 1.000 25.43864 ? 210 TRP A HA   1 
ATOM   2935 H  HB2  . TRP A 1 187 ? -15.63415 -12.37307 21.68888 1.000 23.38868 ? 210 TRP A HB2  1 
ATOM   2936 H  HB3  . TRP A 1 187 ? -15.67236 -11.16713 20.65464 1.000 23.38868 ? 210 TRP A HB3  1 
ATOM   2937 H  HD1  . TRP A 1 187 ? -18.88081 -10.78247 21.13012 1.000 25.96125 ? 210 TRP A HD1  1 
ATOM   2938 H  HE1  . TRP A 1 187 ? -19.62598 -9.55788  23.08292 1.000 26.50275 ? 210 TRP A HE1  1 
ATOM   2939 H  HE3  . TRP A 1 187 ? -14.80517 -11.05468 23.83904 1.000 26.14500 ? 210 TRP A HE3  1 
ATOM   2940 H  HZ2  . TRP A 1 187 ? -18.54609 -8.76954  25.50764 1.000 26.69431 ? 210 TRP A HZ2  1 
ATOM   2941 H  HZ3  . TRP A 1 187 ? -14.77998 -10.10198 25.94663 1.000 26.41418 ? 210 TRP A HZ3  1 
ATOM   2942 H  HH2  . TRP A 1 187 ? -16.60537 -8.93932  26.73789 1.000 21.91685 ? 210 TRP A HH2  1 
ATOM   2943 N  N    . MET A 1 188 ? -15.11568 -13.80057 18.99543 1.000 17.95664 ? 211 MET A N    1 
ATOM   2944 C  CA   . MET A 1 188 ? -14.24473 -14.03485 17.84999 1.000 19.86561 ? 211 MET A CA   1 
ATOM   2945 C  C    . MET A 1 188 ? -14.99906 -14.72253 16.71094 1.000 20.56914 ? 211 MET A C    1 
ATOM   2946 O  O    . MET A 1 188 ? -14.75206 -14.42998 15.53760 1.000 19.72668 ? 211 MET A O    1 
ATOM   2947 C  CB   . MET A 1 188 ? -13.02735 -14.85556 18.25912 1.000 16.39820 ? 211 MET A CB   1 
ATOM   2948 C  CG   . MET A 1 188 ? -12.06944 -14.14076 19.21550 1.000 16.62333 ? 211 MET A CG   1 
ATOM   2949 S  SD   . MET A 1 188 ? -10.53993 -15.00522 19.65448 1.000 15.63754 ? 211 MET A SD   1 
ATOM   2950 C  CE   . MET A 1 188 ? -9.75038  -14.90483 18.05473 1.000 14.83894 ? 211 MET A CE   1 
ATOM   2951 H  H    . MET A 1 188 ? -14.91911 -14.25522 19.69846 1.000 21.52789 ? 211 MET A H    1 
ATOM   2952 H  HA   . MET A 1 188 ? -13.92141 -13.17536 17.53753 1.000 23.81865 ? 211 MET A HA   1 
ATOM   2953 H  HB2  . MET A 1 188 ? -13.33379 -15.66282 18.70108 1.000 19.65776 ? 211 MET A HB2  1 
ATOM   2954 H  HB3  . MET A 1 188 ? -12.52677 -15.08426 17.46036 1.000 19.65776 ? 211 MET A HB3  1 
ATOM   2955 H  HG2  . MET A 1 188 ? -11.80962 -13.30081 18.80577 1.000 19.92791 ? 211 MET A HG2  1 
ATOM   2956 H  HG3  . MET A 1 188 ? -12.54475 -13.97262 20.04418 1.000 19.92791 ? 211 MET A HG3  1 
ATOM   2957 H  HE1  . MET A 1 188 ? -8.85151  -15.26295 18.12316 1.000 17.78665 ? 211 MET A HE1  1 
ATOM   2958 H  HE2  . MET A 1 188 ? -10.26484 -15.42229 17.41562 1.000 17.78665 ? 211 MET A HE2  1 
ATOM   2959 H  HE3  . MET A 1 188 ? -9.71614  -13.97601 17.77718 1.000 17.78665 ? 211 MET A HE3  1 
ATOM   2960 N  N    . LYS A 1 189 ? -15.92524 -15.63658 17.02929 1.000 22.31274 ? 212 LYS A N    1 
ATOM   2961 C  CA   . LYS A 1 189 ? -16.71593 -16.28441 15.97725 1.000 23.45588 ? 212 LYS A CA   1 
ATOM   2962 C  C    . LYS A 1 189 ? -17.60194 -15.29218 15.24325 1.000 22.42269 ? 212 LYS A C    1 
ATOM   2963 O  O    . LYS A 1 189 ? -18.00774 -15.54834 14.10736 1.000 21.76363 ? 212 LYS A O    1 
ATOM   2964 C  CB   . LYS A 1 189 ? -17.58963 -17.40345 16.55786 1.000 25.58928 ? 212 LYS A CB   1 
ATOM   2965 C  CG   . LYS A 1 189 ? -16.78090 -18.63853 16.92238 1.000 32.08775 ? 212 LYS A CG   1 
ATOM   2966 C  CD   . LYS A 1 189 ? -17.55517 -19.63485 17.76914 1.000 39.33272 ? 212 LYS A CD   1 
ATOM   2967 C  CE   . LYS A 1 189 ? -18.77926 -20.16954 17.05940 1.000 47.87699 ? 212 LYS A CE   1 
ATOM   2968 N  NZ   . LYS A 1 189 ? -19.52342 -21.08192 17.97573 1.000 63.54601 ? 212 LYS A NZ   1 
ATOM   2969 H  H    . LYS A 1 189 ? -16.11056 -15.89314 17.82894 1.000 26.75521 ? 212 LYS A H    1 
ATOM   2970 H  HA   . LYS A 1 189 ? -16.10031 -16.68650 15.34462 1.000 28.12698 ? 212 LYS A HA   1 
ATOM   2971 H  HB2  . LYS A 1 189 ? -18.02635 -17.08031 17.36145 1.000 30.68706 ? 212 LYS A HB2  1 
ATOM   2972 H  HB3  . LYS A 1 189 ? -18.25413 -17.66086 15.89977 1.000 30.68706 ? 212 LYS A HB3  1 
ATOM   2973 H  HG2  . LYS A 1 189 ? -16.50961 -19.08874 16.10714 1.000 38.48522 ? 212 LYS A HG2  1 
ATOM   2974 H  HG3  . LYS A 1 189 ? -15.99856 -18.36478 17.42628 1.000 38.48522 ? 212 LYS A HG3  1 
ATOM   2975 H  HD2  . LYS A 1 189 ? -16.97918 -20.38570 17.98212 1.000 47.17919 ? 212 LYS A HD2  1 
ATOM   2976 H  HD3  . LYS A 1 189 ? -17.84714 -19.19884 18.58495 1.000 47.17919 ? 212 LYS A HD3  1 
ATOM   2977 H  HE2  . LYS A 1 189 ? -19.36067 -19.43517 16.80728 1.000 57.43230 ? 212 LYS A HE2  1 
ATOM   2978 H  HE3  . LYS A 1 189 ? -18.51161 -20.66665 16.27064 1.000 57.43230 ? 212 LYS A HE3  1 
ATOM   2979 H  HZ1  . LYS A 1 189 ? -20.25226 -21.39249 17.57021 1.000 76.23513 ? 212 LYS A HZ1  1 
ATOM   2980 H  HZ2  . LYS A 1 189 ? -19.00679 -21.76871 18.20707 1.000 76.23513 ? 212 LYS A HZ2  1 
ATOM   2981 H  HZ3  . LYS A 1 189 ? -19.76670 -20.64303 18.71077 1.000 76.23513 ? 212 LYS A HZ3  1 
ATOM   2982 N  N    . GLY A 1 190 ? -17.91286 -14.17210 15.86316 1.000 20.80160 ? 213 GLY A N    1 
ATOM   2983 C  CA   . GLY A 1 190 ? -18.68002 -13.11842 15.25432 1.000 21.87497 ? 213 GLY A CA   1 
ATOM   2984 C  C    . GLY A 1 190 ? -17.84841 -12.03042 14.62465 1.000 20.42353 ? 213 GLY A C    1 
ATOM   2985 O  O    . GLY A 1 190 ? -18.39398 -10.98258 14.27278 1.000 24.21099 ? 213 GLY A O    1 
ATOM   2986 H  H    . GLY A 1 190 ? -17.67876 -13.99565 16.67165 1.000 24.94184 ? 213 GLY A H    1 
ATOM   2987 H  HA2  . GLY A 1 190 ? -19.24353 -13.50078 14.56355 1.000 26.22988 ? 213 GLY A HA2  1 
ATOM   2988 H  HA3  . GLY A 1 190 ? -19.24269 -12.71015 15.93079 1.000 26.22988 ? 213 GLY A HA3  1 
ATOM   2989 N  N    . ASN A 1 191 ? -16.54270 -12.21594 14.51513 1.000 22.30847 ? 214 ASN A N    1 
ATOM   2990 C  CA   . ASN A 1 191 ? -15.71252 -11.21677 13.86465 1.000 17.69158 ? 214 ASN A CA   1 
ATOM   2991 C  C    . ASN A 1 191 ? -16.25327 -10.93462 12.46851 1.000 26.06860 ? 214 ASN A C    1 
ATOM   2992 O  O    . ASN A 1 191 ? -16.63465 -11.85459 11.74186 1.000 22.35997 ? 214 ASN A O    1 
ATOM   2993 C  CB   . ASN A 1 191 ? -14.28325 -11.70472 13.74003 1.000 22.96565 ? 214 ASN A CB   1 
ATOM   2994 C  CG   . ASN A 1 191 ? -13.40097 -10.72079 13.04261 1.000 18.44679 ? 214 ASN A CG   1 
ATOM   2995 O  OD1  . ASN A 1 191 ? -13.57880 -9.49808  13.17139 1.000 18.66335 ? 214 ASN A OD1  1 
ATOM   2996 N  ND2  . ASN A 1 191 ? -12.45200 -11.23322 12.27191 1.000 18.54132 ? 214 ASN A ND2  1 
ATOM   2997 H  H    . ASN A 1 191 ? -16.11692 -12.90427 14.80585 1.000 26.75008 ? 214 ASN A H    1 
ATOM   2998 H  HA   . ASN A 1 191 ? -15.71612 -10.40586 14.39692 1.000 21.20982 ? 214 ASN A HA   1 
ATOM   2999 H  HB2  . ASN A 1 191 ? -13.92180 -11.85692 14.62721 1.000 27.53870 ? 214 ASN A HB2  1 
ATOM   3000 H  HB3  . ASN A 1 191 ? -14.27353 -12.53075 13.23163 1.000 27.53870 ? 214 ASN A HB3  1 
ATOM   3001 H  HD21 . ASN A 1 191 ? -11.91550 -10.71260 11.84679 1.000 22.22950 ? 214 ASN A HD21 1 
ATOM   3002 H  HD22 . ASN A 1 191 ? -12.37284 -12.08628 12.19701 1.000 22.22950 ? 214 ASN A HD22 1 
ATOM   3003 N  N    . THR A 1 192 ? -16.22756 -9.65914  12.07286 1.000 22.69351 ? 215 THR A N    1 
ATOM   3004 C  CA   . THR A 1 192 ? -16.66380 -9.27928  10.73590 1.000 25.99438 ? 215 THR A CA   1 
ATOM   3005 C  C    . THR A 1 192 ? -15.52459 -8.99550  9.76108  1.000 24.36013 ? 215 THR A C    1 
ATOM   3006 O  O    . THR A 1 192 ? -15.79929 -8.73477  8.58221  1.000 25.46307 ? 215 THR A O    1 
ATOM   3007 C  CB   . THR A 1 192 ? -17.54179 -8.03372  10.79622 1.000 22.82249 ? 215 THR A CB   1 
ATOM   3008 O  OG1  . THR A 1 192 ? -16.72475 -6.88279  11.11053 1.000 21.88712 ? 215 THR A OG1  1 
ATOM   3009 C  CG2  . THR A 1 192 ? -18.64989 -8.17719  11.84971 1.000 22.00978 ? 215 THR A CG2  1 
ATOM   3010 H  H    . THR A 1 192 ? -15.96242 -9.00271  12.56111 1.000 27.21214 ? 215 THR A H    1 
ATOM   3011 H  HA   . THR A 1 192 ? -17.18307 -10.01976 10.38527 1.000 31.17318 ? 215 THR A HA   1 
ATOM   3012 H  HB   . THR A 1 192 ? -17.96986 -7.90777  9.93495  1.000 27.36691 ? 215 THR A HB   1 
ATOM   3013 H  HG1  . THR A 1 192 ? -16.42227 -6.94978  11.89131 1.000 26.24446 ? 215 THR A HG1  1 
ATOM   3014 H  HG21 . THR A 1 192 ? -19.27843 -7.44246  11.77226 1.000 26.39166 ? 215 THR A HG21 1 
ATOM   3015 H  HG22 . THR A 1 192 ? -19.12494 -9.01287  11.71984 1.000 26.39166 ? 215 THR A HG22 1 
ATOM   3016 H  HG23 . THR A 1 192 ? -18.26446 -8.16923  12.73982 1.000 26.39166 ? 215 THR A HG23 1 
ATOM   3017 N  N    . THR A 1 193 ? -14.27047 -9.01991  10.20512 1.000 19.87795 ? 216 THR A N    1 
ATOM   3018 C  CA   . THR A 1 193 ? -13.16560 -8.49733  9.40544  1.000 23.10195 ? 216 THR A CA   1 
ATOM   3019 C  C    . THR A 1 193 ? -12.27732 -9.58202  8.80083  1.000 21.53581 ? 216 THR A C    1 
ATOM   3020 O  O    . THR A 1 193 ? -11.21558 -9.25302  8.24567  1.000 23.74431 ? 216 THR A O    1 
ATOM   3021 C  CB   . THR A 1 193 ? -12.27112 -7.58092  10.24956 1.000 19.97905 ? 216 THR A CB   1 
ATOM   3022 O  OG1  . THR A 1 193 ? -11.53942 -8.38424  11.19709 1.000 22.35983 ? 216 THR A OG1  1 
ATOM   3023 C  CG2  . THR A 1 193 ? -13.08006 -6.51827  10.98896 1.000 21.35055 ? 216 THR A CG2  1 
ATOM   3024 H  H    . THR A 1 193 ? -14.03360 -9.33534  10.96931 1.000 23.83345 ? 216 THR A H    1 
ATOM   3025 H  HA   . THR A 1 193 ? -13.56732 -7.98773  8.68444  1.000 27.70226 ? 216 THR A HA   1 
ATOM   3026 H  HB   . THR A 1 193 ? -11.65570 -7.11113  9.66522  1.000 23.95478 ? 216 THR A HB   1 
ATOM   3027 H  HG1  . THR A 1 193 ? -10.89296 -8.76115  10.81548 1.000 26.81171 ? 216 THR A HG1  1 
ATOM   3028 H  HG21 . THR A 1 193 ? -12.48300 -5.88115  11.41145 1.000 25.60058 ? 216 THR A HG21 1 
ATOM   3029 H  HG22 . THR A 1 193 ? -13.65485 -6.04608  10.36643 1.000 25.60058 ? 216 THR A HG22 1 
ATOM   3030 H  HG23 . THR A 1 193 ? -13.62973 -6.93476  11.67109 1.000 25.60058 ? 216 THR A HG23 1 
ATOM   3031 N  N    . GLY A 1 194 ? -12.63845 -10.85754 8.92519  1.000 17.17985 ? 217 GLY A N    1 
ATOM   3032 C  CA   . GLY A 1 194 ? -11.68750 -11.89982 8.59332  1.000 20.12569 ? 217 GLY A CA   1 
ATOM   3033 C  C    . GLY A 1 194 ? -11.93223 -12.71138 7.33701  1.000 15.74771 ? 217 GLY A C    1 
ATOM   3034 O  O    . GLY A 1 194 ? -11.18185 -13.65580 7.07381  1.000 17.07399 ? 217 GLY A O    1 
ATOM   3035 H  H    . GLY A 1 194 ? -13.40831 -11.13201 9.19274  1.000 20.59574 ? 217 GLY A H    1 
ATOM   3036 H  HA2  . GLY A 1 194 ? -10.81447 -11.48817 8.49705  1.000 24.13075 ? 217 GLY A HA2  1 
ATOM   3037 H  HA3  . GLY A 1 194 ? -11.66117 -12.52684 9.33295  1.000 24.13075 ? 217 GLY A HA3  1 
ATOM   3038 N  N    . ALA A 1 195 ? -12.96622 -12.38308 6.55738  1.000 16.42817 ? 218 ALA A N    1 
ATOM   3039 C  CA   . ALA A 1 195 ? -13.37912 -13.30338 5.50749  1.000 19.05159 ? 218 ALA A CA   1 
ATOM   3040 C  C    . ALA A 1 195 ? -12.31774 -13.46321 4.42574  1.000 19.79545 ? 218 ALA A C    1 
ATOM   3041 O  O    . ALA A 1 195 ? -12.25075 -14.52139 3.77345  1.000 18.54447 ? 218 ALA A O    1 
ATOM   3042 C  CB   . ALA A 1 195 ? -14.68330 -12.81950 4.89573  1.000 18.83339 ? 218 ALA A CB   1 
ATOM   3043 H  H    . ALA A 1 195 ? -13.42633 -11.65893 6.61652  1.000 19.69373 ? 218 ALA A H    1 
ATOM   3044 H  HA   . ALA A 1 195 ? -13.52379 -14.17799 5.90123  1.000 22.84183 ? 218 ALA A HA   1 
ATOM   3045 H  HB1  . ALA A 1 195 ? -14.96590 -13.45006 4.21498  1.000 22.57999 ? 218 ALA A HB1  1 
ATOM   3046 H  HB2  . ALA A 1 195 ? -15.35610 -12.76081 5.59200  1.000 22.57999 ? 218 ALA A HB2  1 
ATOM   3047 H  HB3  . ALA A 1 195 ? -14.54098 -11.94594 4.49881  1.000 22.57999 ? 218 ALA A HB3  1 
ATOM   3048 N  N    . ALA A 1 196 ? -11.47577 -12.45508 4.22594  1.000 18.68292 ? 219 ALA A N    1 
ATOM   3049 C  CA   . ALA A 1 196 ? -10.45904 -12.52344 3.18006  1.000 16.42868 ? 219 ALA A CA   1 
ATOM   3050 C  C    . ALA A 1 196 ? -9.15132  -13.13005 3.65499  1.000 17.81015 ? 219 ALA A C    1 
ATOM   3051 O  O    . ALA A 1 196 ? -8.23006  -13.28809 2.84583  1.000 17.17087 ? 219 ALA A O    1 
ATOM   3052 C  CB   . ALA A 1 196 ? -10.18918 -11.13260 2.60926  1.000 21.32729 ? 219 ALA A CB   1 
ATOM   3053 H  H    . ALA A 1 196 ? -11.47284 -11.72476 4.68006  1.000 22.39943 ? 219 ALA A H    1 
ATOM   3054 H  HA   . ALA A 1 196 ? -10.80284 -13.08056 2.46430  1.000 19.69433 ? 219 ALA A HA   1 
ATOM   3055 H  HB1  . ALA A 1 196 ? -9.49684  -11.19765 1.93300  1.000 25.57267 ? 219 ALA A HB1  1 
ATOM   3056 H  HB2  . ALA A 1 196 ? -11.00600 -10.78933 2.21446  1.000 25.57267 ? 219 ALA A HB2  1 
ATOM   3057 H  HB3  . ALA A 1 196 ? -9.89732  -10.54814 3.32629  1.000 25.57267 ? 219 ALA A HB3  1 
ATOM   3058 N  N    . SER A 1 197 ? -9.04642  -13.48928 4.93442  1.000 16.37077 ? 220 SER A N    1 
ATOM   3059 C  CA   . SER A 1 197 ? -7.76581  -13.91042 5.48463  1.000 15.83043 ? 220 SER A CA   1 
ATOM   3060 C  C    . SER A 1 197 ? -7.72532  -15.42296 5.66519  1.000 16.15139 ? 220 SER A C    1 
ATOM   3061 O  O    . SER A 1 197 ? -7.93266  -16.16481 4.69189  1.000 18.42988 ? 220 SER A O    1 
ATOM   3062 C  CB   . SER A 1 197 ? -7.48797  -13.12556 6.76826  1.000 17.29282 ? 220 SER A CB   1 
ATOM   3063 O  OG   . SER A 1 197 ? -7.26980  -11.75662 6.42003  1.000 18.86247 ? 220 SER A OG   1 
ATOM   3064 H  H    . SER A 1 197 ? -9.69748  -13.49657 5.49625  1.000 19.62484 ? 220 SER A H    1 
ATOM   3065 H  HA   . SER A 1 197 ? -7.03858  -13.70909 4.87511  1.000 18.97643 ? 220 SER A HA   1 
ATOM   3066 H  HB2  . SER A 1 197 ? -8.25149  -13.19270 7.36277  1.000 20.73131 ? 220 SER A HB2  1 
ATOM   3067 H  HB3  . SER A 1 197 ? -6.69695  -13.48117 7.20269  1.000 20.73131 ? 220 SER A HB3  1 
ATOM   3068 H  HG   . SER A 1 197 ? -7.08723  -11.31072 7.10810  1.000 22.61488 ? 220 SER A HG   1 
ATOM   3069 N  N    . ILE A 1 198 ? -7.46322  -15.90692 6.88466  1.000 13.97327 ? 221 ILE A N    1 
ATOM   3070 C  CA   . ILE A 1 198 ? -7.37439  -17.35591 7.08523  1.000 14.87669 ? 221 ILE A CA   1 
ATOM   3071 C  C    . ILE A 1 198 ? -8.61902  -18.05617 6.55972  1.000 20.53720 ? 221 ILE A C    1 
ATOM   3072 O  O    . ILE A 1 198 ? -8.53639  -19.11831 5.92386  1.000 16.34100 ? 221 ILE A O    1 
ATOM   3073 C  CB   . ILE A 1 198 ? -7.13655  -17.67423 8.57494  1.000 16.61550 ? 221 ILE A CB   1 
ATOM   3074 C  CG1  . ILE A 1 198 ? -5.67975  -17.39038 8.92852  1.000 17.29122 ? 221 ILE A CG1  1 
ATOM   3075 C  CG2  . ILE A 1 198 ? -7.45441  -19.10466 8.88364  1.000 14.09199 ? 221 ILE A CG2  1 
ATOM   3076 C  CD1  . ILE A 1 198 ? -5.43666  -17.37611 10.46594 1.000 15.24591 ? 221 ILE A CD1  1 
ATOM   3077 H  H    . ILE A 1 198 ? -7.33673  -15.43207 7.59043  1.000 16.74784 ? 221 ILE A H    1 
ATOM   3078 H  HA   . ILE A 1 198 ? -6.61557  -17.68503 6.57851  1.000 17.83194 ? 221 ILE A HA   1 
ATOM   3079 H  HB   . ILE A 1 198 ? -7.72489  -17.10994 9.10061  1.000 19.91851 ? 221 ILE A HB   1 
ATOM   3080 H  HG12 . ILE A 1 198 ? -5.11870  -18.07987 8.54028  1.000 20.72939 ? 221 ILE A HG12 1 
ATOM   3081 H  HG13 . ILE A 1 198 ? -5.43071  -16.52203 8.57516  1.000 20.72939 ? 221 ILE A HG13 1 
ATOM   3082 H  HG21 . ILE A 1 198 ? -7.10046  -19.32490 9.75949  1.000 16.89030 ? 221 ILE A HG21 1 
ATOM   3083 H  HG22 . ILE A 1 198 ? -8.41716  -19.22283 8.87666  1.000 16.89030 ? 221 ILE A HG22 1 
ATOM   3084 H  HG23 . ILE A 1 198 ? -7.04671  -19.67122 8.21008  1.000 16.89030 ? 221 ILE A HG23 1 
ATOM   3085 H  HD11 . ILE A 1 198 ? -4.55250  -17.01840 10.64256 1.000 18.27501 ? 221 ILE A HD11 1 
ATOM   3086 H  HD12 . ILE A 1 198 ? -6.10934  -16.81824 10.88686 1.000 18.27501 ? 221 ILE A HD12 1 
ATOM   3087 H  HD13 . ILE A 1 198 ? -5.50019  -18.28302 10.80414 1.000 18.27501 ? 221 ILE A HD13 1 
ATOM   3088 N  N    . GLN A 1 199 ? -9.78953  -17.47138 6.81157  1.000 16.45600 ? 222 GLN A N    1 
ATOM   3089 C  CA   . GLN A 1 199 ? -11.03621 -18.09907 6.39152  1.000 15.61962 ? 222 GLN A CA   1 
ATOM   3090 C  C    . GLN A 1 199 ? -11.07095 -18.36235 4.89098  1.000 18.24653 ? 222 GLN A C    1 
ATOM   3091 O  O    . GLN A 1 199 ? -11.74386 -19.30099 4.44738  1.000 18.79900 ? 222 GLN A O    1 
ATOM   3092 C  CB   . GLN A 1 199 ? -12.23384 -17.20658 6.73190  1.000 18.98538 ? 222 GLN A CB   1 
ATOM   3093 C  CG   . GLN A 1 199 ? -12.61479 -17.06726 8.20347  1.000 21.79688 ? 222 GLN A CG   1 
ATOM   3094 C  CD   . GLN A 1 199 ? -13.69299 -15.97896 8.41305  1.000 30.31374 ? 222 GLN A CD   1 
ATOM   3095 O  OE1  . GLN A 1 199 ? -14.65070 -15.89514 7.65176  1.000 28.00907 ? 222 GLN A OE1  1 
ATOM   3096 N  NE2  . GLN A 1 199 ? -13.52376 -15.14330 9.44545  1.000 24.15025 ? 222 GLN A NE2  1 
ATOM   3097 H  H    . GLN A 1 199 ? -9.88697  -16.72036 7.21909  1.000 19.72711 ? 222 GLN A H    1 
ATOM   3098 H  HA   . GLN A 1 199 ? -11.10642 -18.93859 6.87234  1.000 18.72346 ? 222 GLN A HA   1 
ATOM   3099 H  HB2  . GLN A 1 199 ? -12.04027 -16.31326 6.40722  1.000 22.76238 ? 222 GLN A HB2  1 
ATOM   3100 H  HB3  . GLN A 1 199 ? -13.01063 -17.56474 6.27450  1.000 22.76238 ? 222 GLN A HB3  1 
ATOM   3101 H  HG2  . GLN A 1 199 ? -12.96802 -17.91178 8.52427  1.000 26.13618 ? 222 GLN A HG2  1 
ATOM   3102 H  HG3  . GLN A 1 199 ? -11.82903 -16.82026 8.71579  1.000 26.13618 ? 222 GLN A HG3  1 
ATOM   3103 H  HE21 . GLN A 1 199 ? -12.83780 -15.22590 9.95754  1.000 28.96022 ? 222 GLN A HE21 1 
ATOM   3104 H  HE22 . GLN A 1 199 ? -14.10102 -14.52397 9.59645  1.000 28.96022 ? 222 GLN A HE22 1 
ATOM   3105 N  N    . ALA A 1 200 ? -10.42467 -17.50669 4.08966  1.000 18.94307 ? 223 ALA A N    1 
ATOM   3106 C  CA   . ALA A 1 200 ? -10.49790 -17.66900 2.63740  1.000 16.24555 ? 223 ALA A CA   1 
ATOM   3107 C  C    . ALA A 1 200 ? -9.68306  -18.85429 2.14099  1.000 18.09786 ? 223 ALA A C    1 
ATOM   3108 O  O    . ALA A 1 200 ? -9.86372  -19.27190 0.99238  1.000 20.57636 ? 223 ALA A O    1 
ATOM   3109 C  CB   . ALA A 1 200 ? -10.01968 -16.39106 1.92785  1.000 16.18421 ? 223 ALA A CB   1 
ATOM   3110 H  H    . ALA A 1 200 ? -9.94964  -16.84149 4.35699  1.000 22.71160 ? 223 ALA A H    1 
ATOM   3111 H  HA   . ALA A 1 200 ? -11.42640 -17.81768 2.39933  1.000 19.47458 ? 223 ALA A HA   1 
ATOM   3112 H  HB1  . ALA A 1 200 ? -10.02292 -16.54182 0.96965  1.000 19.40097 ? 223 ALA A HB1  1 
ATOM   3113 H  HB2  . ALA A 1 200 ? -10.62053 -15.66274 2.15014  1.000 19.40097 ? 223 ALA A HB2  1 
ATOM   3114 H  HB3  . ALA A 1 200 ? -9.12099  -16.18140 2.22667  1.000 19.40097 ? 223 ALA A HB3  1 
ATOM   3115 N  N    . GLY A 1 201 ? -8.77850  -19.38638 2.95875  1.000 17.86159 ? 224 GLY A N    1 
ATOM   3116 C  CA   . GLY A 1 201 ? -8.02379  -20.58503 2.64689  1.000 17.24803 ? 224 GLY A CA   1 
ATOM   3117 C  C    . GLY A 1 201 ? -8.54205  -21.88123 3.23380  1.000 20.91727 ? 224 GLY A C    1 
ATOM   3118 O  O    . GLY A 1 201 ? -7.87441  -22.91170 3.09712  1.000 20.57933 ? 224 GLY A O    1 
ATOM   3119 H  H    . GLY A 1 201 ? -8.58080  -19.05492 3.72729  1.000 21.41383 ? 224 GLY A H    1 
ATOM   3120 H  HA2  . GLY A 1 201 ? -8.00630  -20.69109 1.68287  1.000 20.67756 ? 224 GLY A HA2  1 
ATOM   3121 H  HA3  . GLY A 1 201 ? -7.11634  -20.46507 2.96792  1.000 20.67756 ? 224 GLY A HA3  1 
ATOM   3122 N  N    . LEU A 1 202 ? -9.72774  -21.88267 3.84700  1.000 17.34044 ? 225 LEU A N    1 
ATOM   3123 C  CA   . LEU A 1 202 ? -10.29798 -23.05781 4.47051  1.000 18.00108 ? 225 LEU A CA   1 
ATOM   3124 C  C    . LEU A 1 202 ? -11.62192 -23.40509 3.80966  1.000 22.44907 ? 225 LEU A C    1 
ATOM   3125 O  O    . LEU A 1 202 ? -12.26349 -22.52939 3.22158  1.000 19.21439 ? 225 LEU A O    1 
ATOM   3126 C  CB   . LEU A 1 202 ? -10.51663 -22.81054 5.97380  1.000 18.75278 ? 225 LEU A CB   1 
ATOM   3127 C  CG   . LEU A 1 202 ? -9.37314  -22.30663 6.80503  1.000 18.47736 ? 225 LEU A CG   1 
ATOM   3128 C  CD1  . LEU A 1 202 ? -9.86096  -22.02856 8.22782  1.000 19.45876 ? 225 LEU A CD1  1 
ATOM   3129 C  CD2  . LEU A 1 202 ? -8.27252  -23.28873 6.84618  1.000 19.12320 ? 225 LEU A CD2  1 
ATOM   3130 H  H    . LEU A 1 202 ? -10.23058 -21.18808 3.91253  1.000 20.78844 ? 225 LEU A H    1 
ATOM   3131 H  HA   . LEU A 1 202 ? -9.70284  -23.81700 4.36883  1.000 21.58121 ? 225 LEU A HA   1 
ATOM   3132 H  HB2  . LEU A 1 202 ? -11.22685 -22.15548 6.05971  1.000 22.48325 ? 225 LEU A HB2  1 
ATOM   3133 H  HB3  . LEU A 1 202 ? -10.79215 -23.65238 6.36915  1.000 22.48325 ? 225 LEU A HB3  1 
ATOM   3134 H  HG   . LEU A 1 202 ? -9.03267  -21.48919 6.40910  1.000 22.15275 ? 225 LEU A HG   1 
ATOM   3135 H  HD11 . LEU A 1 202 ? -9.10506  -21.76289 8.77457  1.000 23.33043 ? 225 LEU A HD11 1 
ATOM   3136 H  HD12 . LEU A 1 202 ? -10.51791 -21.31534 8.20269  1.000 23.33043 ? 225 LEU A HD12 1 
ATOM   3137 H  HD13 . LEU A 1 202 ? -10.26205 -22.83521 8.58747  1.000 23.33043 ? 225 LEU A HD13 1 
ATOM   3138 H  HD21 . LEU A 1 202 ? -7.56011  -22.94142 7.40542  1.000 22.92776 ? 225 LEU A HD21 1 
ATOM   3139 H  HD22 . LEU A 1 202 ? -8.60613  -24.12167 7.21471  1.000 22.92776 ? 225 LEU A HD22 1 
ATOM   3140 H  HD23 . LEU A 1 202 ? -7.94470  -23.43362 5.94483  1.000 22.92776 ? 225 LEU A HD23 1 
ATOM   3141 N  N    . PRO A 1 203 ? -12.04588 -24.67271 3.85768  1.000 19.75372 ? 226 PRO A N    1 
ATOM   3142 C  CA   . PRO A 1 203 ? -13.36613 -25.01683 3.33348  1.000 19.59703 ? 226 PRO A CA   1 
ATOM   3143 C  C    . PRO A 1 203 ? -14.44099 -24.12142 3.94407  1.000 22.39697 ? 226 PRO A C    1 
ATOM   3144 O  O    . PRO A 1 203 ? -14.34650 -23.68891 5.08655  1.000 19.22048 ? 226 PRO A O    1 
ATOM   3145 C  CB   . PRO A 1 203 ? -13.54895 -26.49178 3.73979  1.000 20.35820 ? 226 PRO A CB   1 
ATOM   3146 C  CG   . PRO A 1 203 ? -12.13445 -27.00533 3.87630  1.000 19.84616 ? 226 PRO A CG   1 
ATOM   3147 C  CD   . PRO A 1 203 ? -11.32514 -25.84561 4.37010  1.000 21.64812 ? 226 PRO A CD   1 
ATOM   3148 H  HA   . PRO A 1 203 ? -13.38677 -24.94759 2.36617  1.000 23.49635 ? 226 PRO A HA   1 
ATOM   3149 H  HB2  . PRO A 1 203 ? -14.02714 -26.55064 4.58168  1.000 24.40976 ? 226 PRO A HB2  1 
ATOM   3150 H  HB3  . PRO A 1 203 ? -14.03228 -26.97210 3.04944  1.000 24.40976 ? 226 PRO A HB3  1 
ATOM   3151 H  HG2  . PRO A 1 203 ? -12.11169 -27.73641 4.51341  1.000 23.79531 ? 226 PRO A HG2  1 
ATOM   3152 H  HG3  . PRO A 1 203 ? -11.81112 -27.30734 3.01308  1.000 23.79531 ? 226 PRO A HG3  1 
ATOM   3153 H  HD2  . PRO A 1 203 ? -11.29677 -25.83468 5.33962  1.000 25.95766 ? 226 PRO A HD2  1 
ATOM   3154 H  HD3  . PRO A 1 203 ? -10.42418 -25.87841 4.01218  1.000 25.95766 ? 226 PRO A HD3  1 
ATOM   3155 N  N    . ALA A 1 204 ? -15.47245 -23.84199 3.15635  1.000 20.40000 ? 227 ALA A N    1 
ATOM   3156 C  CA   . ALA A 1 204 ? -16.57395 -23.01856 3.63815  1.000 20.74348 ? 227 ALA A CA   1 
ATOM   3157 C  C    . ALA A 1 204 ? -17.27947 -23.63507 4.84816  1.000 21.62516 ? 227 ALA A C    1 
ATOM   3158 O  O    . ALA A 1 204 ? -17.86618 -22.91181 5.65073  1.000 22.77507 ? 227 ALA A O    1 
ATOM   3159 C  CB   . ALA A 1 204 ? -17.58557 -22.81707 2.51117  1.000 23.99915 ? 227 ALA A CB   1 
ATOM   3160 H  H    . ALA A 1 204 ? -15.55929 -24.11407 2.34515  1.000 24.45992 ? 227 ALA A H    1 
ATOM   3161 H  HA   . ALA A 1 204 ? -16.21544 -22.15919 3.90994  1.000 24.87209 ? 227 ALA A HA   1 
ATOM   3162 H  HB1  . ALA A 1 204 ? -18.31423 -22.26519 2.83579  1.000 28.77890 ? 227 ALA A HB1  1 
ATOM   3163 H  HB2  . ALA A 1 204 ? -17.14526 -22.37889 1.76617  1.000 28.77890 ? 227 ALA A HB2  1 
ATOM   3164 H  HB3  . ALA A 1 204 ? -17.92454 -23.68219 2.23267  1.000 28.77890 ? 227 ALA A HB3  1 
ATOM   3165 N  N    . SER A 1 205 ? -17.24554 -24.95297 5.00025  1.000 22.95141 ? 228 SER A N    1 
ATOM   3166 C  CA   . SER A 1 205 ? -17.99881 -25.57005 6.08487  1.000 27.42453 ? 228 SER A CA   1 
ATOM   3167 C  C    . SER A 1 205 ? -17.36309 -25.35421 7.44925  1.000 25.46967 ? 228 SER A C    1 
ATOM   3168 O  O    . SER A 1 205 ? -18.02510 -25.59293 8.46890  1.000 26.02924 ? 228 SER A O    1 
ATOM   3169 C  CB   . SER A 1 205 ? -18.14754 -27.07693 5.85222  1.000 24.98299 ? 228 SER A CB   1 
ATOM   3170 O  OG   . SER A 1 205 ? -16.88634 -27.72083 5.94615  1.000 28.26673 ? 228 SER A OG   1 
ATOM   3171 H  H    . SER A 1 205 ? -16.80555 -25.49866 4.50201  1.000 27.52161 ? 228 SER A H    1 
ATOM   3172 H  HA   . SER A 1 205 ? -18.88322 -25.17167 6.08805  1.000 32.88935 ? 228 SER A HA   1 
ATOM   3173 H  HB2  . SER A 1 205 ? -18.74222 -27.44452 6.52463  1.000 29.95950 ? 228 SER A HB2  1 
ATOM   3174 H  HB3  . SER A 1 205 ? -18.51488 -27.22647 4.96700  1.000 29.95950 ? 228 SER A HB3  1 
ATOM   3175 H  HG   . SER A 1 205 ? -16.42010 -27.53925 5.27143  1.000 33.90000 ? 228 SER A HG   1 
ATOM   3176 N  N    . TRP A 1 206 ? -16.11276 -24.92675 7.49775  1.000 20.62909 ? 229 TRP A N    1 
ATOM   3177 C  CA   . TRP A 1 206 ? -15.39880 -24.87293 8.76291  1.000 20.90135 ? 229 TRP A CA   1 
ATOM   3178 C  C    . TRP A 1 206 ? -15.73949 -23.59767 9.52018  1.000 24.25022 ? 229 TRP A C    1 
ATOM   3179 O  O    . TRP A 1 206 ? -15.87202 -22.52450 8.94012  1.000 23.88827 ? 229 TRP A O    1 
ATOM   3180 C  CB   . TRP A 1 206 ? -13.89113 -24.95027 8.53315  1.000 20.20868 ? 229 TRP A CB   1 
ATOM   3181 C  CG   . TRP A 1 206 ? -13.40240 -26.26642 7.98856  1.000 23.51417 ? 229 TRP A CG   1 
ATOM   3182 C  CD1  . TRP A 1 206 ? -14.15432 -27.27925 7.45523  1.000 26.57499 ? 229 TRP A CD1  1 
ATOM   3183 C  CD2  . TRP A 1 206 ? -12.04145 -26.70954 7.93439  1.000 19.05808 ? 229 TRP A CD2  1 
ATOM   3184 N  NE1  . TRP A 1 206 ? -13.34884 -28.31442 7.07901  1.000 21.95616 ? 229 TRP A NE1  1 
ATOM   3185 C  CE2  . TRP A 1 206 ? -12.04435 -27.98769 7.35865  1.000 22.36718 ? 229 TRP A CE2  1 
ATOM   3186 C  CE3  . TRP A 1 206 ? -10.82549 -26.15394 8.33990  1.000 18.11597 ? 229 TRP A CE3  1 
ATOM   3187 C  CZ2  . TRP A 1 206 ? -10.87706 -28.72048 7.15725  1.000 23.20983 ? 229 TRP A CZ2  1 
ATOM   3188 C  CZ3  . TRP A 1 206 ? -9.66135  -26.88310 8.13071  1.000 18.91431 ? 229 TRP A CZ3  1 
ATOM   3189 C  CH2  . TRP A 1 206 ? -9.69567  -28.15062 7.55110  1.000 21.56150 ? 229 TRP A CH2  1 
ATOM   3190 H  H    . TRP A 1 206 ? -15.65742 -24.66375 6.81724  1.000 24.73483 ? 229 TRP A H    1 
ATOM   3191 H  HA   . TRP A 1 206 ? -15.66323 -25.63080 9.30753  1.000 25.06154 ? 229 TRP A HA   1 
ATOM   3192 H  HB2  . TRP A 1 206 ? -13.64057 -24.26092 7.89839  1.000 24.23034 ? 229 TRP A HB2  1 
ATOM   3193 H  HB3  . TRP A 1 206 ? -13.44246 -24.80040 9.37999  1.000 24.23034 ? 229 TRP A HB3  1 
ATOM   3194 H  HD1  . TRP A 1 206 ? -15.07959 -27.26374 7.36288  1.000 31.86991 ? 229 TRP A HD1  1 
ATOM   3195 H  HE1  . TRP A 1 206 ? -13.61468 -29.05148 6.72450  1.000 26.32732 ? 229 TRP A HE1  1 
ATOM   3196 H  HE3  . TRP A 1 206 ? -10.79589 -25.31525 8.74068  1.000 21.71908 ? 229 TRP A HE3  1 
ATOM   3197 H  HZ2  . TRP A 1 206 ? -10.89913 -29.56556 6.76963  1.000 27.83171 ? 229 TRP A HZ2  1 
ATOM   3198 H  HZ3  . TRP A 1 206 ? -8.84354  -26.51861 8.38217  1.000 22.67710 ? 229 TRP A HZ3  1 
ATOM   3199 H  HH2  . TRP A 1 206 ? -8.90098  -28.61817 7.42958  1.000 25.85372 ? 229 TRP A HH2  1 
ATOM   3200 N  N    . VAL A 1 207 ? -15.84910 -23.72480 10.83230 1.000 25.11390 ? 230 VAL A N    1 
ATOM   3201 C  CA   . VAL A 1 207 ? -16.17603 -22.61292 11.70308 1.000 21.55511 ? 230 VAL A CA   1 
ATOM   3202 C  C    . VAL A 1 207 ? -14.87903 -21.99807 12.21307 1.000 25.83454 ? 230 VAL A C    1 
ATOM   3203 O  O    . VAL A 1 207 ? -13.94698 -22.71115 12.60410 1.000 23.37067 ? 230 VAL A O    1 
ATOM   3204 C  CB   . VAL A 1 207 ? -17.06680 -23.07715 12.86386 1.000 26.57563 ? 230 VAL A CB   1 
ATOM   3205 C  CG1  . VAL A 1 207 ? -17.40319 -21.91363 13.76985 1.000 25.11521 ? 230 VAL A CG1  1 
ATOM   3206 C  CG2  . VAL A 1 207 ? -18.32485 -23.70303 12.31668 1.000 33.02290 ? 230 VAL A CG2  1 
ATOM   3207 H  H    . VAL A 1 207 ? -15.73526 -24.46646 11.25251 1.000 30.11660 ? 230 VAL A H    1 
ATOM   3208 H  HA   . VAL A 1 207 ? -16.65685 -21.93591 11.20171 1.000 25.84606 ? 230 VAL A HA   1 
ATOM   3209 H  HB   . VAL A 1 207 ? -16.59233 -23.73864 13.39132 1.000 31.87067 ? 230 VAL A HB   1 
ATOM   3210 H  HG11 . VAL A 1 207 ? -18.12869 -22.17204 14.35957 1.000 30.11817 ? 230 VAL A HG11 1 
ATOM   3211 H  HG12 . VAL A 1 207 ? -16.61887 -21.68279 14.29183 1.000 30.11817 ? 230 VAL A HG12 1 
ATOM   3212 H  HG13 . VAL A 1 207 ? -17.67271 -21.15726 13.22563 1.000 30.11817 ? 230 VAL A HG13 1 
ATOM   3213 H  HG21 . VAL A 1 207 ? -18.90942 -23.93460 13.05529 1.000 39.60740 ? 230 VAL A HG21 1 
ATOM   3214 H  HG22 . VAL A 1 207 ? -18.76604 -23.06648 11.73267 1.000 39.60740 ? 230 VAL A HG22 1 
ATOM   3215 H  HG23 . VAL A 1 207 ? -18.08951 -24.50122 11.81828 1.000 39.60740 ? 230 VAL A HG23 1 
ATOM   3216 N  N    . VAL A 1 208 ? -14.80164 -20.67381 12.16054 1.000 19.54665 ? 231 VAL A N    1 
ATOM   3217 C  CA   . VAL A 1 208 ? -13.59007 -19.94521 12.50218 1.000 19.65845 ? 231 VAL A CA   1 
ATOM   3218 C  C    . VAL A 1 208 ? -13.93680 -18.80054 13.44385 1.000 23.44485 ? 231 VAL A C    1 
ATOM   3219 O  O    . VAL A 1 208 ? -14.94617 -18.12368 13.25953 1.000 19.61078 ? 231 VAL A O    1 
ATOM   3220 C  CB   . VAL A 1 208 ? -12.89703 -19.40412 11.24274 1.000 24.58720 ? 231 VAL A CB   1 
ATOM   3221 C  CG1  . VAL A 1 208 ? -11.72832 -18.52204 11.60613 1.000 22.74709 ? 231 VAL A CG1  1 
ATOM   3222 C  CG2  . VAL A 1 208 ? -12.50650 -20.57077 10.32019 1.000 27.12839 ? 231 VAL A CG2  1 
ATOM   3223 H  H    . VAL A 1 208 ? -15.45374 -20.16535 11.92425 1.000 23.43590 ? 231 VAL A H    1 
ATOM   3224 H  HA   . VAL A 1 208 ? -12.98452 -20.54226 12.96881 1.000 23.57006 ? 231 VAL A HA   1 
ATOM   3225 H  HB   . VAL A 1 208 ? -13.50967 -18.84022 10.74516 1.000 29.48456 ? 231 VAL A HB   1 
ATOM   3226 H  HG11 . VAL A 1 208 ? -11.14215 -18.44190 10.83744 1.000 27.27643 ? 231 VAL A HG11 1 
ATOM   3227 H  HG12 . VAL A 1 208 ? -12.06039 -17.64716 11.86152 1.000 27.27643 ? 231 VAL A HG12 1 
ATOM   3228 H  HG13 . VAL A 1 208 ? -11.24850 -18.92311 12.34762 1.000 27.27643 ? 231 VAL A HG13 1 
ATOM   3229 H  HG21 . VAL A 1 208 ? -12.05054 -20.21765 9.54025  1.000 32.53399 ? 231 VAL A HG21 1 
ATOM   3230 H  HG22 . VAL A 1 208 ? -11.91826 -21.17207 10.80322 1.000 32.53399 ? 231 VAL A HG22 1 
ATOM   3231 H  HG23 . VAL A 1 208 ? -13.31008 -21.04137 10.04873 1.000 32.53399 ? 231 VAL A HG23 1 
ATOM   3232 N  N    . GLY A 1 209 ? -13.08109 -18.57936 14.43141 1.000 16.46087 ? 232 GLY A N    1 
ATOM   3233 C  CA   . GLY A 1 209 ? -13.08747 -17.38697 15.26003 1.000 20.19742 ? 232 GLY A CA   1 
ATOM   3234 C  C    . GLY A 1 209 ? -11.70752 -16.77997 15.08540 1.000 18.44085 ? 232 GLY A C    1 
ATOM   3235 O  O    . GLY A 1 209 ? -10.70512 -17.43106 15.41096 1.000 18.51244 ? 232 GLY A O    1 
ATOM   3236 H  H    . GLY A 1 209 ? -12.45863 -19.13055 14.65125 1.000 19.73296 ? 232 GLY A H    1 
ATOM   3237 H  HA2  . GLY A 1 209 ? -13.76948 -16.76226 14.96762 1.000 24.21682 ? 232 GLY A HA2  1 
ATOM   3238 H  HA3  . GLY A 1 209 ? -13.24179 -17.60985 16.19138 1.000 24.21682 ? 232 GLY A HA3  1 
ATOM   3239 N  N    . ASP A 1 210 ? -11.62497 -15.57661 14.53322 1.000 15.67210 ? 233 ASP A N    1 
ATOM   3240 C  CA   . ASP A 1 210 ? -10.33537 -14.99625 14.21378 1.000 15.89356 ? 233 ASP A CA   1 
ATOM   3241 C  C    . ASP A 1 210 ? -10.30813 -13.52484 14.56676 1.000 14.98582 ? 233 ASP A C    1 
ATOM   3242 O  O    . ASP A 1 210 ? -11.35205 -12.88307 14.73998 1.000 17.73409 ? 233 ASP A O    1 
ATOM   3243 C  CB   . ASP A 1 210 ? -9.99731  -15.17183 12.71211 1.000 14.33944 ? 233 ASP A CB   1 
ATOM   3244 C  CG   . ASP A 1 210 ? -10.63415 -14.12176 11.84277 1.000 16.28950 ? 233 ASP A CG   1 
ATOM   3245 O  OD1  . ASP A 1 210 ? -11.88124 -14.14138 11.72371 1.000 18.10488 ? 233 ASP A OD1  1 
ATOM   3246 O  OD2  . ASP A 1 210 ? -9.90214  -13.25790 11.28188 1.000 16.84872 ? 233 ASP A OD2  1 
ATOM   3247 H  H    . ASP A 1 210 ? -12.30008 -15.08161 14.33624 1.000 18.78644 ? 233 ASP A H    1 
ATOM   3248 H  HA   . ASP A 1 210 ? -9.66041  -15.43841 14.75213 1.000 19.05219 ? 233 ASP A HA   1 
ATOM   3249 H  HB2  . ASP A 1 210 ? -9.03601  -15.11399 12.59608 1.000 17.18725 ? 233 ASP A HB2  1 
ATOM   3250 H  HB3  . ASP A 1 210 ? -10.31562 -16.03900 12.41616 1.000 17.18725 ? 233 ASP A HB3  1 
ATOM   3251 N  N    . LYS A 1 211 ? -9.07669  -13.00096 14.64724 1.000 19.08538 ? 234 LYS A N    1 
ATOM   3252 C  CA   . LYS A 1 211 ? -8.81608  -11.57225 14.76646 1.000 15.76548 ? 234 LYS A CA   1 
ATOM   3253 C  C    . LYS A 1 211 ? -7.74408  -11.19342 13.75498 1.000 14.08587 ? 234 LYS A C    1 
ATOM   3254 O  O    . LYS A 1 211 ? -6.61094  -11.67087 13.84872 1.000 13.79968 ? 234 LYS A O    1 
ATOM   3255 C  CB   . LYS A 1 211 ? -8.32680  -11.17986 16.15489 1.000 16.28766 ? 234 LYS A CB   1 
ATOM   3256 C  CG   . LYS A 1 211 ? -8.02418  -9.67000  16.25420 1.000 17.73499 ? 234 LYS A CG   1 
ATOM   3257 C  CD   . LYS A 1 211 ? -9.29730  -8.85298  16.34023 1.000 19.65932 ? 234 LYS A CD   1 
ATOM   3258 C  CE   . LYS A 1 211 ? -9.07510  -7.38666  15.90276 1.000 19.42713 ? 234 LYS A CE   1 
ATOM   3259 N  NZ   . LYS A 1 211 ? -9.06070  -7.10790  14.44528 1.000 19.39402 ? 234 LYS A NZ   1 
ATOM   3260 H  H    . LYS A 1 211 ? -8.35838  -13.47367 14.63383 1.000 22.88237 ? 234 LYS A H    1 
ATOM   3261 H  HA   . LYS A 1 211 ? -9.64323  -11.10059 14.58139 1.000 18.89849 ? 234 LYS A HA   1 
ATOM   3262 H  HB2  . LYS A 1 211 ? -9.01150  -11.39604 16.80708 1.000 19.52511 ? 234 LYS A HB2  1 
ATOM   3263 H  HB3  . LYS A 1 211 ? -7.51219  -11.66683 16.35526 1.000 19.52511 ? 234 LYS A HB3  1 
ATOM   3264 H  HG2  . LYS A 1 211 ? -7.49809  -9.49948  17.05111 1.000 21.26191 ? 234 LYS A HG2  1 
ATOM   3265 H  HG3  . LYS A 1 211 ? -7.53370  -9.38810  15.46626 1.000 21.26191 ? 234 LYS A HG3  1 
ATOM   3266 H  HD2  . LYS A 1 211 ? -9.96778  -9.24417  15.75857 1.000 23.57111 ? 234 LYS A HD2  1 
ATOM   3267 H  HD3  . LYS A 1 211 ? -9.61403  -8.85071  17.25706 1.000 23.57111 ? 234 LYS A HD3  1 
ATOM   3268 H  HE2  . LYS A 1 211 ? -9.78731  -6.84970  16.28399 1.000 23.29248 ? 234 LYS A HE2  1 
ATOM   3269 H  HE3  . LYS A 1 211 ? -8.21783  -7.09701  16.25219 1.000 23.29248 ? 234 LYS A HE3  1 
ATOM   3270 H  HZ1  . LYS A 1 211 ? -9.85904  -7.28441  14.09371 1.000 23.25274 ? 234 LYS A HZ1  1 
ATOM   3271 H  HZ2  . LYS A 1 211 ? -8.86443  -6.25189  14.30101 1.000 23.25274 ? 234 LYS A HZ2  1 
ATOM   3272 H  HZ3  . LYS A 1 211 ? -8.44978  -7.61587  14.04424 1.000 23.25274 ? 234 LYS A HZ3  1 
ATOM   3273 N  N    . THR A 1 212 ? -8.09142  -10.31731 12.82524 1.000 16.79943 ? 235 THR A N    1 
ATOM   3274 C  CA   . THR A 1 212 ? -7.10021  -9.85214  11.86286 1.000 15.46110 ? 235 THR A CA   1 
ATOM   3275 C  C    . THR A 1 212 ? -6.26606  -8.70458  12.41505 1.000 16.61740 ? 235 THR A C    1 
ATOM   3276 O  O    . THR A 1 212 ? -6.58585  -8.09485  13.44324 1.000 16.26896 ? 235 THR A O    1 
ATOM   3277 C  CB   . THR A 1 212 ? -7.80868  -9.39647  10.58560 1.000 17.85144 ? 235 THR A CB   1 
ATOM   3278 O  OG1  . THR A 1 212 ? -8.75950  -8.38809  10.93603 1.000 20.20211 ? 235 THR A OG1  1 
ATOM   3279 C  CG2  . THR A 1 212 ? -8.53572  -10.58416 9.99939  1.000 17.09594 ? 235 THR A CG2  1 
ATOM   3280 H  H    . THR A 1 212 ? -8.87787  -9.98245  12.73052 1.000 20.13924 ? 235 THR A H    1 
ATOM   3281 H  HA   . THR A 1 212 ? -6.49499  -10.58397 11.66528 1.000 18.53324 ? 235 THR A HA   1 
ATOM   3282 H  HB   . THR A 1 212 ? -7.18345  -9.04317  9.93356  1.000 21.40164 ? 235 THR A HB   1 
ATOM   3283 H  HG1  . THR A 1 212 ? -8.36121  -7.69380  11.19082 1.000 24.22245 ? 235 THR A HG1  1 
ATOM   3284 H  HG21 . THR A 1 212 ? -8.92995  -10.34383 9.14632  1.000 20.49505 ? 235 THR A HG21 1 
ATOM   3285 H  HG22 . THR A 1 212 ? -7.91658  -11.31854 9.86433  1.000 20.49505 ? 235 THR A HG22 1 
ATOM   3286 H  HG23 . THR A 1 212 ? -9.23956  -10.87247 10.60138 1.000 20.49505 ? 235 THR A HG23 1 
ATOM   3287 N  N    . GLY A 1 213 ? -5.18755  -8.40840  11.70325 1.000 14.98038 ? 236 GLY A N    1 
ATOM   3288 C  CA   . GLY A 1 213 ? -4.42072  -7.20137  11.96145 1.000 14.49432 ? 236 GLY A CA   1 
ATOM   3289 C  C    . GLY A 1 213 ? -3.79178  -6.69945  10.68246 1.000 19.82262 ? 236 GLY A C    1 
ATOM   3290 O  O    . GLY A 1 213 ? -3.45622  -7.48111  9.79587  1.000 16.38933 ? 236 GLY A O    1 
ATOM   3291 H  H    . GLY A 1 213 ? -4.87853  -8.89235  11.06302 1.000 17.95638 ? 236 GLY A H    1 
ATOM   3292 H  HA2  . GLY A 1 213 ? -5.00163  -6.51130  12.31817 1.000 17.37311 ? 236 GLY A HA2  1 
ATOM   3293 H  HA3  . GLY A 1 213 ? -3.71919  -7.38739  12.60499 1.000 17.37311 ? 236 GLY A HA3  1 
ATOM   3294 N  N    . SER A 1 214 ? -3.64621  -5.38399  10.57778 1.000 16.53259 ? 237 SER A N    1 
ATOM   3295 C  CA   . SER A 1 214 ? -2.87816  -4.82294  9.46949  1.000 25.83225 ? 237 SER A CA   1 
ATOM   3296 C  C    . SER A 1 214 ? -2.26784  -3.49768  9.89225  1.000 16.85410 ? 237 SER A C    1 
ATOM   3297 O  O    . SER A 1 214 ? -2.74579  -2.82666  10.81152 1.000 20.17709 ? 237 SER A O    1 
ATOM   3298 C  CB   . SER A 1 214 ? -3.72412  -4.66155  8.20920  1.000 24.42202 ? 237 SER A CB   1 
ATOM   3299 O  OG   . SER A 1 214 ? -4.91344  -3.97098  8.48456  1.000 31.32025 ? 237 SER A OG   1 
ATOM   3300 H  H    . SER A 1 214 ? -3.97488  -4.80611  11.12335 1.000 19.81902 ? 237 SER A H    1 
ATOM   3301 H  HA   . SER A 1 214 ? -2.14836  -5.42610  9.25855  1.000 30.97862 ? 237 SER A HA   1 
ATOM   3302 H  HB2  . SER A 1 214 ? -3.21578  -4.16275  7.55064  1.000 29.28634 ? 237 SER A HB2  1 
ATOM   3303 H  HB3  . SER A 1 214 ? -3.94355  -5.54057  7.86270  1.000 29.28634 ? 237 SER A HB3  1 
ATOM   3304 H  HG   . SER A 1 214 ? -5.27589  -3.72580  7.76754  1.000 37.56422 ? 237 SER A HG   1 
ATOM   3305 N  N    . GLY A 1 215 ? -1.17671  -3.12935  9.22324  1.000 23.35752 ? 238 GLY A N    1 
ATOM   3306 C  CA   . GLY A 1 215 ? -0.51681  -1.88739  9.58314  1.000 16.76638 ? 238 GLY A CA   1 
ATOM   3307 C  C    . GLY A 1 215 ? 0.56578   -1.48805  8.60727  1.000 20.82296 ? 238 GLY A C    1 
ATOM   3308 O  O    . GLY A 1 215 ? 0.48061   -1.82398  7.42479  1.000 18.13893 ? 238 GLY A O    1 
ATOM   3309 H  H    . GLY A 1 215 ? -0.81460  -3.56961  8.57931  1.000 28.00895 ? 238 GLY A H    1 
ATOM   3310 H  HA2  . GLY A 1 215 ? -1.17443  -1.17503  9.61435  1.000 20.09958 ? 238 GLY A HA2  1 
ATOM   3311 H  HA3  . GLY A 1 215 ? -0.11371  -1.98371  10.46014 1.000 20.09958 ? 238 GLY A HA3  1 
ATOM   3312 N  N    . GLY A 1 216 ? 1.55760   -0.73454  9.08106  1.000 19.96356 ? 239 GLY A N    1 
ATOM   3313 C  CA   . GLY A 1 216 ? 2.61424   -0.25124  8.21001  1.000 18.87126 ? 239 GLY A CA   1 
ATOM   3314 C  C    . GLY A 1 216 ? 3.41447   -1.38789  7.59507  1.000 17.88805 ? 239 GLY A C    1 
ATOM   3315 O  O    . GLY A 1 216 ? 3.36408   -2.53320  8.01879  1.000 17.03642 ? 239 GLY A O    1 
ATOM   3316 H  H    . GLY A 1 216 ? 1.63818   -0.49161  9.90209  1.000 23.93619 ? 239 GLY A H    1 
ATOM   3317 H  HA2  . GLY A 1 216 ? 2.22555   0.27334   7.49263  1.000 22.62543 ? 239 GLY A HA2  1 
ATOM   3318 H  HA3  . GLY A 1 216 ? 3.21993   0.30986   8.71914  1.000 22.62543 ? 239 GLY A HA3  1 
ATOM   3319 N  N    . TYR A 1 217 ? 4.16762   -1.04765  6.54893  1.000 18.62166 ? 240 TYR A N    1 
ATOM   3320 C  CA   . TYR A 1 217 ? 4.95286   -2.03002  5.80082  1.000 20.67748 ? 240 TYR A CA   1 
ATOM   3321 C  C    . TYR A 1 217 ? 4.08916   -3.19610  5.32429  1.000 17.81171 ? 240 TYR A C    1 
ATOM   3322 O  O    . TYR A 1 217 ? 4.51028   -4.34899  5.29450  1.000 19.34780 ? 240 TYR A O    1 
ATOM   3323 C  CB   . TYR A 1 217 ? 6.15568   -2.49139  6.63794  1.000 19.82778 ? 240 TYR A CB   1 
ATOM   3324 C  CG   . TYR A 1 217 ? 7.22070   -1.39154  6.74637  1.000 19.74347 ? 240 TYR A CG   1 
ATOM   3325 C  CD1  . TYR A 1 217 ? 7.09560   -0.36407  7.66513  1.000 19.70570 ? 240 TYR A CD1  1 
ATOM   3326 C  CD2  . TYR A 1 217 ? 8.32051   -1.37157  5.90343  1.000 21.15545 ? 240 TYR A CD2  1 
ATOM   3327 C  CE1  . TYR A 1 217 ? 8.03312   0.63681   7.75981  1.000 21.28716 ? 240 TYR A CE1  1 
ATOM   3328 C  CE2  . TYR A 1 217 ? 9.26987   -0.34555  5.97776  1.000 21.57178 ? 240 TYR A CE2  1 
ATOM   3329 C  CZ   . TYR A 1 217 ? 9.12507   0.64098   6.91320  1.000 25.10226 ? 240 TYR A CZ   1 
ATOM   3330 O  OH   . TYR A 1 217 ? 10.06771  1.65607   7.00195  1.000 28.01274 ? 240 TYR A OH   1 
ATOM   3331 H  H    . TYR A 1 217 ? 4.24140   -0.24492  6.24930  1.000 22.32591 ? 240 TYR A H    1 
ATOM   3332 H  HA   . TYR A 1 217 ? 5.29805   -1.61499  4.99491  1.000 24.79289 ? 240 TYR A HA   1 
ATOM   3333 H  HB2  . TYR A 1 217 ? 5.85616   -2.71605  7.53277  1.000 23.77326 ? 240 TYR A HB2  1 
ATOM   3334 H  HB3  . TYR A 1 217 ? 6.55930   -3.26737  6.21860  1.000 23.77326 ? 240 TYR A HB3  1 
ATOM   3335 H  HD1  . TYR A 1 217 ? 6.35892   -0.35043  8.23258  1.000 23.62676 ? 240 TYR A HD1  1 
ATOM   3336 H  HD2  . TYR A 1 217 ? 8.42966   -2.05112  5.27797  1.000 25.36646 ? 240 TYR A HD2  1 
ATOM   3337 H  HE1  . TYR A 1 217 ? 7.93252   1.31044   8.39306  1.000 25.52451 ? 240 TYR A HE1  1 
ATOM   3338 H  HE2  . TYR A 1 217 ? 9.99431   -0.33501  5.39468  1.000 25.86605 ? 240 TYR A HE2  1 
ATOM   3339 H  HH   . TYR A 1 217 ? 10.68839  1.52062   6.45239  1.000 33.59521 ? 240 TYR A HH   1 
ATOM   3340 N  N    . GLY A 1 218 ? 2.87851   -2.88311  4.90394  1.000 18.83038 ? 241 GLY A N    1 
ATOM   3341 C  CA   . GLY A 1 218 ? 1.96883   -3.88528  4.37627  1.000 19.77073 ? 241 GLY A CA   1 
ATOM   3342 C  C    . GLY A 1 218 ? 1.79333   -5.07592  5.29458  1.000 19.86807 ? 241 GLY A C    1 
ATOM   3343 O  O    . GLY A 1 218 ? 1.57939   -6.19902  4.84597  1.000 17.86405 ? 241 GLY A O    1 
ATOM   3344 H  H    . GLY A 1 218 ? 2.55317   -2.08707  4.91284  1.000 22.57638 ? 241 GLY A H    1 
ATOM   3345 H  HA2  . GLY A 1 218 ? 1.09827   -3.48122  4.23569  1.000 23.70479 ? 241 GLY A HA2  1 
ATOM   3346 H  HA3  . GLY A 1 218 ? 2.30878   -4.20661  3.52652  1.000 23.70479 ? 241 GLY A HA3  1 
ATOM   3347 N  N    . THR A 1 219 ? 1.91483   -4.84570  6.59510  1.000 16.74747 ? 242 THR A N    1 
ATOM   3348 C  CA   . THR A 1 219 ? 1.75814   -5.92862  7.55039  1.000 19.57623 ? 242 THR A CA   1 
ATOM   3349 C  C    . THR A 1 219 ? 0.32090   -6.40285  7.49877  1.000 18.61309 ? 242 THR A C    1 
ATOM   3350 O  O    . THR A 1 219 ? -0.60234  -5.59889  7.54761  1.000 16.91393 ? 242 THR A O    1 
ATOM   3351 C  CB   . THR A 1 219 ? 2.15478   -5.45407  8.94356  1.000 19.65217 ? 242 THR A CB   1 
ATOM   3352 O  OG1  . THR A 1 219 ? 3.56734   -5.13384  8.94595  1.000 18.23615 ? 242 THR A OG1  1 
ATOM   3353 C  CG2  . THR A 1 219 ? 1.85156   -6.52147  9.99269  1.000 15.96777 ? 242 THR A CG2  1 
ATOM   3354 H  H    . THR A 1 219 ? 2.08595   -4.07908  6.94528  1.000 20.07689 ? 242 THR A H    1 
ATOM   3355 H  HA   . THR A 1 219 ? 2.33632   -6.67785  7.33761  1.000 23.47139 ? 242 THR A HA   1 
ATOM   3356 H  HB   . THR A 1 219 ? 1.64411   -4.66466  9.18220  1.000 23.56253 ? 242 THR A HB   1 
ATOM   3357 H  HG1  . THR A 1 219 ? 3.72102   -4.50825  8.40685  1.000 21.86330 ? 242 THR A HG1  1 
ATOM   3358 H  HG21 . THR A 1 219 ? 2.47357   -6.44509  10.73308 1.000 19.14124 ? 242 THR A HG21 1 
ATOM   3359 H  HG22 . THR A 1 219 ? 0.94811   -6.41010  10.32778 1.000 19.14124 ? 242 THR A HG22 1 
ATOM   3360 H  HG23 . THR A 1 219 ? 1.93537   -7.40490  9.60100  1.000 19.14124 ? 242 THR A HG23 1 
ATOM   3361 N  N    . THR A 1 220 ? 0.14072   -7.71638  7.34920  1.000 16.07044 ? 243 THR A N    1 
ATOM   3362 C  CA   . THR A 1 220 ? -1.16768  -8.34367  7.18062  1.000 16.77722 ? 243 THR A CA   1 
ATOM   3363 C  C    . THR A 1 220 ? -1.16921  -9.62199  8.00646  1.000 15.43676 ? 243 THR A C    1 
ATOM   3364 O  O    . THR A 1 220 ? -0.35087  -10.50990 7.76075  1.000 15.23292 ? 243 THR A O    1 
ATOM   3365 C  CB   . THR A 1 220 ? -1.42310  -8.66056  5.70462  1.000 20.57776 ? 243 THR A CB   1 
ATOM   3366 O  OG1  . THR A 1 220 ? -1.01984  -7.54381  4.89182  1.000 18.16094 ? 243 THR A OG1  1 
ATOM   3367 C  CG2  . THR A 1 220 ? -2.87199  -8.94149  5.49279  1.000 17.86987 ? 243 THR A CG2  1 
ATOM   3368 H  H    . THR A 1 220 ? 0.78599   -8.28486  7.34195  1.000 19.26445 ? 243 THR A H    1 
ATOM   3369 H  HA   . THR A 1 220 ? -1.87291  -7.75830  7.49827  1.000 20.11258 ? 243 THR A HA   1 
ATOM   3370 H  HB   . THR A 1 220 ? -0.91314  -9.44173  5.43888  1.000 24.67323 ? 243 THR A HB   1 
ATOM   3371 H  HG1  . THR A 1 220 ? -0.20200  -7.38787  5.00323  1.000 21.77305 ? 243 THR A HG1  1 
ATOM   3372 H  HG21 . THR A 1 220 ? -3.05038  -9.06982  4.54801  1.000 21.42377 ? 243 THR A HG21 1 
ATOM   3373 H  HG22 . THR A 1 220 ? -3.12800  -9.74424  5.97336  1.000 21.42377 ? 243 THR A HG22 1 
ATOM   3374 H  HG23 . THR A 1 220 ? -3.40475  -8.19795  5.81559  1.000 21.42377 ? 243 THR A HG23 1 
ATOM   3375 N  N    . ASN A 1 221 ? -2.04903  -9.69843  9.01999  1.000 15.31893 ? 244 ASN A N    1 
ATOM   3376 C  CA   . ASN A 1 221 ? -1.98140  -10.71115 10.06011 1.000 17.91627 ? 244 ASN A CA   1 
ATOM   3377 C  C    . ASN A 1 221 ? -3.35689  -11.31388 10.31223 1.000 15.45776 ? 244 ASN A C    1 
ATOM   3378 O  O    . ASN A 1 221 ? -4.37020  -10.66676 10.07480 1.000 15.31821 ? 244 ASN A O    1 
ATOM   3379 C  CB   . ASN A 1 221 ? -1.52199  -10.09046 11.39859 1.000 13.12247 ? 244 ASN A CB   1 
ATOM   3380 C  CG   . ASN A 1 221 ? -0.11465  -9.55115  11.37283 1.000 16.92103 ? 244 ASN A CG   1 
ATOM   3381 O  OD1  . ASN A 1 221 ? 0.73351   -9.98131  10.58407 1.000 16.06901 ? 244 ASN A OD1  1 
ATOM   3382 N  ND2  . ASN A 1 221 ? 0.15519   -8.63502  12.29132 1.000 15.37038 ? 244 ASN A ND2  1 
ATOM   3383 H  H    . ASN A 1 221 ? -2.70804  -9.15497  9.11981  1.000 18.36263 ? 244 ASN A H    1 
ATOM   3384 H  HA   . ASN A 1 221 ? -1.37160  -11.40654 9.76775  1.000 21.47945 ? 244 ASN A HA   1 
ATOM   3385 H  HB2  . ASN A 1 221 ? -2.11509  -9.35582  11.62097 1.000 15.72688 ? 244 ASN A HB2  1 
ATOM   3386 H  HB3  . ASN A 1 221 ? -1.56412  -10.77127 12.08824 1.000 15.72688 ? 244 ASN A HB3  1 
ATOM   3387 H  HD21 . ASN A 1 221 ? 0.93987   -8.28547  12.33247 1.000 18.42438 ? 244 ASN A HD21 1 
ATOM   3388 H  HD22 . ASN A 1 221 ? -0.45435  -8.38998  12.84631 1.000 18.42438 ? 244 ASN A HD22 1 
ATOM   3389 N  N    . ASP A 1 222 ? -3.39119  -12.54163 10.82822 1.000 15.77781 ? 245 ASP A N    1 
ATOM   3390 C  CA   . ASP A 1 222 ? -4.64070  -13.14194 11.28053 1.000 14.80513 ? 245 ASP A CA   1 
ATOM   3391 C  C    . ASP A 1 222 ? -4.28825  -14.23249 12.28966 1.000 14.55950 ? 245 ASP A C    1 
ATOM   3392 O  O    . ASP A 1 222 ? -3.29595  -14.93996 12.12795 1.000 14.92418 ? 245 ASP A O    1 
ATOM   3393 C  CB   . ASP A 1 222 ? -5.43902  -13.71556 10.09131 1.000 14.67668 ? 245 ASP A CB   1 
ATOM   3394 C  CG   . ASP A 1 222 ? -6.91332  -13.93568 10.38967 1.000 16.03099 ? 245 ASP A CG   1 
ATOM   3395 O  OD1  . ASP A 1 222 ? -7.45108  -13.46090 11.42457 1.000 14.45758 ? 245 ASP A OD1  1 
ATOM   3396 O  OD2  . ASP A 1 222 ? -7.55564  -14.60713 9.54536  1.000 13.57990 ? 245 ASP A OD2  1 
ATOM   3397 H  H    . ASP A 1 222 ? -2.70221  -13.04685 10.92647 1.000 18.91329 ? 245 ASP A H    1 
ATOM   3398 H  HA   . ASP A 1 222 ? -5.20278  -12.48523 11.72064 1.000 17.74607 ? 245 ASP A HA   1 
ATOM   3399 H  HB2  . ASP A 1 222 ? -5.37758  -13.09670 9.34692  1.000 17.59194 ? 245 ASP A HB2  1 
ATOM   3400 H  HB3  . ASP A 1 222 ? -5.05690  -14.57191 9.84322  1.000 17.59194 ? 245 ASP A HB3  1 
ATOM   3401 N  N    . ILE A 1 223 ? -5.09228  -14.34468 13.33262 1.000 13.17541 ? 246 ILE A N    1 
ATOM   3402 C  CA   . ILE A 1 223 ? -4.93597  -15.39685 14.32674 1.000 12.81022 ? 246 ILE A CA   1 
ATOM   3403 C  C    . ILE A 1 223 ? -6.31001  -16.00197 14.55876 1.000 13.52840 ? 246 ILE A C    1 
ATOM   3404 O  O    . ILE A 1 223 ? -7.30448  -15.27642 14.66604 1.000 15.44261 ? 246 ILE A O    1 
ATOM   3405 C  CB   . ILE A 1 223 ? -4.31212  -14.90876 15.64700 1.000 16.19380 ? 246 ILE A CB   1 
ATOM   3406 C  CG1  . ILE A 1 223 ? -5.22260  -14.01554 16.49063 1.000 14.90883 ? 246 ILE A CG1  1 
ATOM   3407 C  CG2  . ILE A 1 223 ? -2.98336  -14.18570 15.37158 1.000 15.37101 ? 246 ILE A CG2  1 
ATOM   3408 C  CD1  . ILE A 1 223 ? -4.56958  -13.54542 17.82907 1.000 15.06212 ? 246 ILE A CD1  1 
ATOM   3409 H  H    . ILE A 1 223 ? -5.74972  -13.81339 13.49109 1.000 15.79041 ? 246 ILE A H    1 
ATOM   3410 H  HA   . ILE A 1 223 ? -4.33513  -16.07489 13.98011 1.000 15.35218 ? 246 ILE A HA   1 
ATOM   3411 H  HB   . ILE A 1 223 ? -4.16612  -15.71130 16.17188 1.000 19.41248 ? 246 ILE A HB   1 
ATOM   3412 H  HG12 . ILE A 1 223 ? -5.44818  -13.22457 15.97645 1.000 17.87052 ? 246 ILE A HG12 1 
ATOM   3413 H  HG13 . ILE A 1 223 ? -6.02813  -14.50913 16.71060 1.000 17.87052 ? 246 ILE A HG13 1 
ATOM   3414 H  HG21 . ILE A 1 223 ? -2.47267  -14.13899 16.19493 1.000 18.42513 ? 246 ILE A HG21 1 
ATOM   3415 H  HG22 . ILE A 1 223 ? -2.48679  -14.68171 14.70203 1.000 18.42513 ? 246 ILE A HG22 1 
ATOM   3416 H  HG23 . ILE A 1 223 ? -3.17189  -13.29088 15.04807 1.000 18.42513 ? 246 ILE A HG23 1 
ATOM   3417 H  HD11 . ILE A 1 223 ? -5.23778  -13.08761 18.36276 1.000 18.05446 ? 246 ILE A HD11 1 
ATOM   3418 H  HD12 . ILE A 1 223 ? -4.23807  -14.32094 18.30820 1.000 18.05446 ? 246 ILE A HD12 1 
ATOM   3419 H  HD13 . ILE A 1 223 ? -3.83674  -12.94250 17.62823 1.000 18.05446 ? 246 ILE A HD13 1 
ATOM   3420 N  N    . ALA A 1 224 ? -6.37348  -17.32745 14.65107 1.000 14.42808 ? 247 ALA A N    1 
ATOM   3421 C  CA   . ALA A 1 224 ? -7.66661  -17.96231 14.60863 1.000 13.88251 ? 247 ALA A CA   1 
ATOM   3422 C  C    . ALA A 1 224 ? -7.71159  -19.23280 15.43804 1.000 14.90165 ? 247 ALA A C    1 
ATOM   3423 O  O    . ALA A 1 224 ? -6.73198  -19.98576 15.53242 1.000 16.44142 ? 247 ALA A O    1 
ATOM   3424 C  CB   . ALA A 1 224 ? -8.04133  -18.30987 13.16189 1.000 15.02510 ? 247 ALA A CB   1 
ATOM   3425 H  H    . ALA A 1 224 ? -5.69958  -17.85497 14.73578 1.000 17.29362 ? 247 ALA A H    1 
ATOM   3426 H  HA   . ALA A 1 224 ? -8.30727  -17.34968 15.00252 1.000 16.63894 ? 247 ALA A HA   1 
ATOM   3427 H  HB1  . ALA A 1 224 ? -8.90275  -18.75578 13.15721 1.000 18.01004 ? 247 ALA A HB1  1 
ATOM   3428 H  HB2  . ALA A 1 224 ? -8.08951  -17.49180 12.64291 1.000 18.01004 ? 247 ALA A HB2  1 
ATOM   3429 H  HB3  . ALA A 1 224 ? -7.36311  -18.89663 12.79226 1.000 18.01004 ? 247 ALA A HB3  1 
ATOM   3430 N  N    . VAL A 1 225 ? -8.89218  -19.50542 15.97257 1.000 15.26980 ? 248 VAL A N    1 
ATOM   3431 C  CA   . VAL A 1 225 ? -9.25407  -20.82322 16.46533 1.000 17.04058 ? 248 VAL A CA   1 
ATOM   3432 C  C    . VAL A 1 225 ? -10.21886 -21.40700 15.43522 1.000 19.94031 ? 248 VAL A C    1 
ATOM   3433 O  O    . VAL A 1 225 ? -11.13395 -20.71627 14.98245 1.000 16.89912 ? 248 VAL A O    1 
ATOM   3434 C  CB   . VAL A 1 225 ? -9.85177  -20.76450 17.88436 1.000 19.33802 ? 248 VAL A CB   1 
ATOM   3435 C  CG1  . VAL A 1 225 ? -11.04096 -19.81553 17.93932 1.000 25.05849 ? 248 VAL A CG1  1 
ATOM   3436 C  CG2  . VAL A 1 225 ? -10.26403 -22.16039 18.32505 1.000 21.46331 ? 248 VAL A CG2  1 
ATOM   3437 H  H    . VAL A 1 225 ? -9.51937  -18.92399 16.06300 1.000 18.30368 ? 248 VAL A H    1 
ATOM   3438 H  HA   . VAL A 1 225 ? -8.47721  -21.40060 16.52870 1.000 20.42861 ? 248 VAL A HA   1 
ATOM   3439 H  HB   . VAL A 1 225 ? -9.17905  -20.42600 18.49573 1.000 23.18554 ? 248 VAL A HB   1 
ATOM   3440 H  HG11 . VAL A 1 225 ? -11.41328 -19.82734 18.83494 1.000 30.05011 ? 248 VAL A HG11 1 
ATOM   3441 H  HG12 . VAL A 1 225 ? -10.74098 -18.92013 17.71758 1.000 30.05011 ? 248 VAL A HG12 1 
ATOM   3442 H  HG13 . VAL A 1 225 ? -11.70867 -20.10859 17.29964 1.000 30.05011 ? 248 VAL A HG13 1 
ATOM   3443 H  HG21 . VAL A 1 225 ? -10.56269 -22.12509 19.24725 1.000 25.73589 ? 248 VAL A HG21 1 
ATOM   3444 H  HG22 . VAL A 1 225 ? -10.98506 -22.47130 17.75552 1.000 25.73589 ? 248 VAL A HG22 1 
ATOM   3445 H  HG23 . VAL A 1 225 ? -9.50118  -22.75441 18.24692 1.000 25.73589 ? 248 VAL A HG23 1 
ATOM   3446 N  N    . ILE A 1 226 ? -9.99409  -22.65957 15.04362 1.000 16.37780 ? 249 ILE A N    1 
ATOM   3447 C  CA   . ILE A 1 226 ? -10.68932 -23.26661 13.91377 1.000 19.86270 ? 249 ILE A CA   1 
ATOM   3448 C  C    . ILE A 1 226 ? -11.28231 -24.59942 14.32793 1.000 23.30840 ? 249 ILE A C    1 
ATOM   3449 O  O    . ILE A 1 226 ? -10.58019 -25.45375 14.88255 1.000 18.72394 ? 249 ILE A O    1 
ATOM   3450 C  CB   . ILE A 1 226 ? -9.74473  -23.47765 12.72515 1.000 17.91090 ? 249 ILE A CB   1 
ATOM   3451 C  CG1  . ILE A 1 226 ? -9.10418  -22.17562 12.28274 1.000 15.46437 ? 249 ILE A CG1  1 
ATOM   3452 C  CG2  . ILE A 1 226 ? -10.50418 -24.10726 11.52094 1.000 22.94706 ? 249 ILE A CG2  1 
ATOM   3453 C  CD1  . ILE A 1 226 ? -7.85760  -22.40652 11.46604 1.000 19.74247 ? 249 ILE A CD1  1 
ATOM   3454 H  H    . ILE A 1 226 ? -9.43196  -23.18671 15.42537 1.000 19.63328 ? 249 ILE A H    1 
ATOM   3455 H  HA   . ILE A 1 226 ? -11.41890 -22.68108 13.65729 1.000 23.81516 ? 249 ILE A HA   1 
ATOM   3456 H  HB   . ILE A 1 226 ? -9.04778  -24.08221 13.02460 1.000 21.47300 ? 249 ILE A HB   1 
ATOM   3457 H  HG12 . ILE A 1 226 ? -9.73535  -21.67889 11.73888 1.000 18.53716 ? 249 ILE A HG12 1 
ATOM   3458 H  HG13 . ILE A 1 226 ? -8.86179  -21.65764 13.06623 1.000 18.53716 ? 249 ILE A HG13 1 
ATOM   3459 H  HG21 . ILE A 1 226 ? -9.93648  -24.07018 10.73529 1.000 27.51639 ? 249 ILE A HG21 1 
ATOM   3460 H  HG22 . ILE A 1 226 ? -10.71909 -25.02965 11.73050 1.000 27.51639 ? 249 ILE A HG22 1 
ATOM   3461 H  HG23 . ILE A 1 226 ? -11.31916 -23.60515 11.36414 1.000 27.51639 ? 249 ILE A HG23 1 
ATOM   3462 H  HD11 . ILE A 1 226 ? -7.47931  -21.54854 11.21773 1.000 23.67089 ? 249 ILE A HD11 1 
ATOM   3463 H  HD12 . ILE A 1 226 ? -7.21986  -22.90771 11.99801 1.000 23.67089 ? 249 ILE A HD12 1 
ATOM   3464 H  HD13 . ILE A 1 226 ? -8.09051  -22.90838 10.66930 1.000 23.67089 ? 249 ILE A HD13 1 
ATOM   3465 N  N    . TRP A 1 227 ? -12.58199 -24.76398 14.06784 1.000 18.44292 ? 250 TRP A N    1 
ATOM   3466 C  CA   . TRP A 1 227 ? -13.28365 -26.02206 14.23733 1.000 20.26579 ? 250 TRP A CA   1 
ATOM   3467 C  C    . TRP A 1 227 ? -13.55566 -26.63368 12.87888 1.000 25.92840 ? 250 TRP A C    1 
ATOM   3468 O  O    . TRP A 1 227 ? -14.55841 -26.29882 12.23756 1.000 23.61347 ? 250 TRP A O    1 
ATOM   3469 C  CB   . TRP A 1 227 ? -14.58595 -25.80781 15.00258 1.000 24.72642 ? 250 TRP A CB   1 
ATOM   3470 C  CG   . TRP A 1 227 ? -14.31298 -25.37316 16.42538 1.000 34.98569 ? 250 TRP A CG   1 
ATOM   3471 C  CD1  . TRP A 1 227 ? -14.08376 -26.18238 17.50393 1.000 32.56144 ? 250 TRP A CD1  1 
ATOM   3472 C  CD2  . TRP A 1 227 ? -14.22509 -24.02405 16.91014 1.000 31.67143 ? 250 TRP A CD2  1 
ATOM   3473 N  NE1  . TRP A 1 227 ? -13.88984 -25.41445 18.63593 1.000 32.66546 ? 250 TRP A NE1  1 
ATOM   3474 C  CE2  . TRP A 1 227 ? -13.96635 -24.09028 18.29032 1.000 30.73578 ? 250 TRP A CE2  1 
ATOM   3475 C  CE3  . TRP A 1 227 ? -14.35615 -22.76953 16.30854 1.000 33.64040 ? 250 TRP A CE3  1 
ATOM   3476 C  CZ2  . TRP A 1 227 ? -13.82693 -22.95380 19.07201 1.000 32.17187 ? 250 TRP A CZ2  1 
ATOM   3477 C  CZ3  . TRP A 1 227 ? -14.22345 -21.65173 17.08074 1.000 37.94731 ? 250 TRP A CZ3  1 
ATOM   3478 C  CH2  . TRP A 1 227 ? -13.95710 -21.74643 18.45258 1.000 38.52532 ? 250 TRP A CH2  1 
ATOM   3479 H  H    . TRP A 1 227 ? -13.09166 -24.13321 13.78156 1.000 22.11143 ? 250 TRP A H    1 
ATOM   3480 H  HA   . TRP A 1 227 ? -12.72786 -26.63536 14.74315 1.000 24.29887 ? 250 TRP A HA   1 
ATOM   3481 H  HB2  . TRP A 1 227 ? -15.10762 -25.11722 14.56459 1.000 29.65162 ? 250 TRP A HB2  1 
ATOM   3482 H  HB3  . TRP A 1 227 ? -15.08713 -26.63800 15.02525 1.000 29.65162 ? 250 TRP A HB3  1 
ATOM   3483 H  HD1  . TRP A 1 227 ? -14.06171 -27.11179 17.47900 1.000 39.05365 ? 250 TRP A HD1  1 
ATOM   3484 H  HE1  . TRP A 1 227 ? -13.74490 -25.71755 19.42759 1.000 39.17847 ? 250 TRP A HE1  1 
ATOM   3485 H  HE3  . TRP A 1 227 ? -14.53074 -22.69747 15.39792 1.000 40.34840 ? 250 TRP A HE3  1 
ATOM   3486 H  HZ2  . TRP A 1 227 ? -13.65144 -23.01281 19.98339 1.000 38.58616 ? 250 TRP A HZ2  1 
ATOM   3487 H  HZ3  . TRP A 1 227 ? -14.31142 -20.81277 16.68918 1.000 45.51669 ? 250 TRP A HZ3  1 
ATOM   3488 H  HH2  . TRP A 1 227 ? -13.86695 -20.96744 18.95254 1.000 46.21030 ? 250 TRP A HH2  1 
ATOM   3489 N  N    . PRO A 1 228 ? -12.71640 -27.54498 12.41157 1.000 22.07523 ? 251 PRO A N    1 
ATOM   3490 C  CA   . PRO A 1 228 ? -12.97844 -28.19227 11.13078 1.000 31.51616 ? 251 PRO A CA   1 
ATOM   3491 C  C    . PRO A 1 228 ? -14.16356 -29.12444 11.25771 1.000 29.87887 ? 251 PRO A C    1 
ATOM   3492 O  O    . PRO A 1 228 ? -14.53470 -29.56563 12.35069 1.000 29.43649 ? 251 PRO A O    1 
ATOM   3493 C  CB   . PRO A 1 228 ? -11.68084 -28.95248 10.84194 1.000 27.12422 ? 251 PRO A CB   1 
ATOM   3494 C  CG   . PRO A 1 228 ? -10.68788 -28.46521 11.85297 1.000 29.24098 ? 251 PRO A CG   1 
ATOM   3495 C  CD   . PRO A 1 228 ? -11.48370 -28.04746 13.03641 1.000 21.74317 ? 251 PRO A CD   1 
ATOM   3496 H  HA   . PRO A 1 228 ? -13.12862 -27.55108 10.41858 1.000 37.79931 ? 251 PRO A HA   1 
ATOM   3497 H  HB2  . PRO A 1 228 ? -11.83189 -29.90565 10.93966 1.000 32.52899 ? 251 PRO A HB2  1 
ATOM   3498 H  HB3  . PRO A 1 228 ? -11.37996 -28.75489 9.94120  1.000 32.52899 ? 251 PRO A HB3  1 
ATOM   3499 H  HG2  . PRO A 1 228 ? -10.07840 -29.18323 12.08509 1.000 35.06910 ? 251 PRO A HG2  1 
ATOM   3500 H  HG3  . PRO A 1 228 ? -10.19288 -27.71433 11.48958 1.000 35.06910 ? 251 PRO A HG3  1 
ATOM   3501 H  HD2  . PRO A 1 228 ? -11.66797 -28.80114 13.61857 1.000 26.07172 ? 251 PRO A HD2  1 
ATOM   3502 H  HD3  . PRO A 1 228 ? -11.03200 -27.34730 13.53305 1.000 26.07172 ? 251 PRO A HD3  1 
ATOM   3503 N  N    . LYS A 1 229 ? -14.78314 -29.41190 10.12249 1.000 31.68229 ? 252 LYS A N    1 
ATOM   3504 C  CA   . LYS A 1 229 ? -15.90231 -30.33088 10.13748 1.000 28.24794 ? 252 LYS A CA   1 
ATOM   3505 C  C    . LYS A 1 229 ? -15.44223 -31.68268 10.68419 1.000 30.84794 ? 252 LYS A C    1 
ATOM   3506 O  O    . LYS A 1 229 ? -14.47155 -32.25766 10.19003 1.000 33.21757 ? 252 LYS A O    1 
ATOM   3507 C  CB   . LYS A 1 229 ? -16.48823 -30.49091 8.73169  1.000 36.46664 ? 252 LYS A CB   1 
ATOM   3508 C  CG   . LYS A 1 229 ? -17.75694 -31.33047 8.73998  1.000 42.30833 ? 252 LYS A CG   1 
ATOM   3509 C  CD   . LYS A 1 229 ? -18.27715 -31.62459 7.32876  1.000 44.75542 ? 252 LYS A CD   1 
ATOM   3510 C  CE   . LYS A 1 229 ? -19.52572 -32.50547 7.38140  1.000 58.00296 ? 252 LYS A CE   1 
ATOM   3511 N  NZ   . LYS A 1 229 ? -20.02434 -32.89601 6.03127  1.000 75.81523 ? 252 LYS A NZ   1 
ATOM   3512 H  H    . LYS A 1 229 ? -14.57788 -29.09440 9.35005  1.000 37.99867 ? 252 LYS A H    1 
ATOM   3513 H  HA   . LYS A 1 229 ? -16.60337 -29.97749 10.70715 1.000 33.87744 ? 252 LYS A HA   1 
ATOM   3514 H  HB2  . LYS A 1 229 ? -16.70495 -29.61547 8.37459  1.000 43.73988 ? 252 LYS A HB2  1 
ATOM   3515 H  HB3  . LYS A 1 229 ? -15.83679 -30.92949 8.16233  1.000 43.73988 ? 252 LYS A HB3  1 
ATOM   3516 H  HG2  . LYS A 1 229 ? -17.57373 -32.17781 9.17513  1.000 50.74991 ? 252 LYS A HG2  1 
ATOM   3517 H  HG3  . LYS A 1 229 ? -18.45011 -30.85298 9.22208  1.000 50.74991 ? 252 LYS A HG3  1 
ATOM   3518 H  HD2  . LYS A 1 229 ? -18.50689 -30.79148 6.88824  1.000 53.68642 ? 252 LYS A HD2  1 
ATOM   3519 H  HD3  . LYS A 1 229 ? -17.59342 -32.09018 6.82217  1.000 53.68642 ? 252 LYS A HD3  1 
ATOM   3520 H  HE2  . LYS A 1 229 ? -19.31761 -33.31786 7.86886  1.000 69.58347 ? 252 LYS A HE2  1 
ATOM   3521 H  HE3  . LYS A 1 229 ? -20.23453 -32.02042 7.83219  1.000 69.58347 ? 252 LYS A HE3  1 
ATOM   3522 H  HZ1  . LYS A 1 229 ? -20.75294 -33.40100 6.11020  1.000 90.95819 ? 252 LYS A HZ1  1 
ATOM   3523 H  HZ2  . LYS A 1 229 ? -20.22654 -32.16898 5.55942  1.000 90.95819 ? 252 LYS A HZ2  1 
ATOM   3524 H  HZ3  . LYS A 1 229 ? -19.39888 -33.35719 5.59744  1.000 90.95819 ? 252 LYS A HZ3  1 
ATOM   3525 N  N    . ASP A 1 230 ? -16.10503 -32.14283 11.74499 1.000 32.33665 ? 253 ASP A N    1 
ATOM   3526 C  CA   . ASP A 1 230 ? -15.83511 -33.42940 12.39158 1.000 34.06466 ? 253 ASP A CA   1 
ATOM   3527 C  C    . ASP A 1 230 ? -14.36366 -33.66922 12.72633 1.000 39.40505 ? 253 ASP A C    1 
ATOM   3528 O  O    . ASP A 1 230 ? -13.85589 -34.78537 12.60631 1.000 32.08948 ? 253 ASP A O    1 
ATOM   3529 C  CB   . ASP A 1 230 ? -16.36696 -34.57543 11.53222 1.000 51.39278 ? 253 ASP A CB   1 
ATOM   3530 C  CG   . ASP A 1 230 ? -17.86780 -34.60177 11.47143 1.000 47.13878 ? 253 ASP A CG   1 
ATOM   3531 O  OD1  . ASP A 1 230 ? -18.50871 -34.52840 12.54175 1.000 58.89721 ? 253 ASP A OD1  1 
ATOM   3532 O  OD2  . ASP A 1 230 ? -18.40214 -34.69804 10.35177 1.000 52.74923 ? 253 ASP A OD2  1 
ATOM   3533 H  H    . ASP A 1 230 ? -16.74342 -31.71069 12.12619 1.000 38.78390 ? 253 ASP A H    1 
ATOM   3534 H  HA   . ASP A 1 230 ? -16.29620 -33.40492 13.24463 1.000 40.85752 ? 253 ASP A HA   1 
ATOM   3535 H  HB2  . ASP A 1 230 ? -16.03101 -34.47558 10.62775 1.000 61.65126 ? 253 ASP A HB2  1 
ATOM   3536 H  HB3  . ASP A 1 230 ? -16.06626 -35.41821 11.90666 1.000 61.65126 ? 253 ASP A HB3  1 
ATOM   3537 N  N    . ARG A 1 231 ? -13.67292 -32.64441 13.21112 1.000 29.88778 ? 254 ARG A N    1 
ATOM   3538 C  CA   A ARG A 1 231 ? -12.29292 -32.81965 13.62729 0.505 34.41444 ? 254 ARG A CA   1 
ATOM   3539 C  CA   B ARG A 1 231 ? -12.27724 -32.78179 13.59508 0.495 34.40806 ? 254 ARG A CA   1 
ATOM   3540 C  C    . ARG A 1 231 ? -12.01917 -31.98662 14.86705 1.000 24.43322 ? 254 ARG A C    1 
ATOM   3541 O  O    . ARG A 1 231 ? -12.78030 -31.08531 15.21857 1.000 24.81729 ? 254 ARG A O    1 
ATOM   3542 C  CB   A ARG A 1 231 ? -11.31305 -32.44300 12.51229 0.505 34.80637 ? 254 ARG A CB   1 
ATOM   3543 C  CB   B ARG A 1 231 ? -11.31439 -32.28669 12.50629 0.495 34.81626 ? 254 ARG A CB   1 
ATOM   3544 C  CG   A ARG A 1 231 ? -11.14269 -33.52928 11.46481 0.505 37.65198 ? 254 ARG A CG   1 
ATOM   3545 C  CG   B ARG A 1 231 ? -11.29710 -33.09596 11.21720 0.495 37.50960 ? 254 ARG A CG   1 
ATOM   3546 C  CD   A ARG A 1 231 ? -10.88493 -32.93630 10.09173 0.505 43.75428 ? 254 ARG A CD   1 
ATOM   3547 C  CD   B ARG A 1 231 ? -10.20160 -32.56414 10.28599 0.495 39.00395 ? 254 ARG A CD   1 
ATOM   3548 N  NE   A ARG A 1 231 ? -12.08790 -32.33238 9.52804  0.505 45.82330 ? 254 ARG A NE   1 
ATOM   3549 N  NE   B ARG A 1 231 ? -10.11137 -33.30242 9.02911  0.495 45.92719 ? 254 ARG A NE   1 
ATOM   3550 C  CZ   A ARG A 1 231 ? -12.29612 -32.14220 8.23121  0.505 33.40486 ? 254 ARG A CZ   1 
ATOM   3551 C  CZ   B ARG A 1 231 ? -9.36630  -34.38506 8.84014  0.495 51.54197 ? 254 ARG A CZ   1 
ATOM   3552 N  NH1  A ARG A 1 231 ? -11.40397 -32.50838 7.32619  0.505 43.38756 ? 254 ARG A NH1  1 
ATOM   3553 N  NH1  B ARG A 1 231 ? -8.62600  -34.89802 9.81097  0.495 44.00557 ? 254 ARG A NH1  1 
ATOM   3554 N  NH2  A ARG A 1 231 ? -13.43175 -31.57963 7.83484  0.505 40.84004 ? 254 ARG A NH2  1 
ATOM   3555 N  NH2  B ARG A 1 231 ? -9.36690  -34.97246 7.64627  0.495 55.33188 ? 254 ARG A NH2  1 
ATOM   3556 H  H    A ARG A 1 231 ? -13.98060 -31.84705 13.30679 0.505 35.84526 ? 254 ARG A H    1 
ATOM   3557 H  H    B ARG A 1 231 ? -13.99382 -31.85502 13.32724 0.495 35.84526 ? 254 ARG A H    1 
ATOM   3558 H  HA   A ARG A 1 231 ? -12.15110 -33.75099 13.85834 0.505 41.27725 ? 254 ARG A HA   1 
ATOM   3559 H  HA   B ARG A 1 231 ? -12.10472 -33.72184 13.76073 0.495 41.26960 ? 254 ARG A HA   1 
ATOM   3560 H  HB2  A ARG A 1 231 ? -11.63937 -31.64673 12.06466 0.505 41.74756 ? 254 ARG A HB2  1 
ATOM   3561 H  HB2  B ARG A 1 231 ? -11.56220 -31.37863 12.27192 0.495 41.75944 ? 254 ARG A HB2  1 
ATOM   3562 H  HB3  A ARG A 1 231 ? -10.44331 -32.26978 12.90530 0.505 41.74756 ? 254 ARG A HB3  1 
ATOM   3563 H  HB3  B ARG A 1 231 ? -10.41416 -32.30227 12.86716 0.495 41.75944 ? 254 ARG A HB3  1 
ATOM   3564 H  HG2  A ARG A 1 231 ? -10.38758 -34.08994 11.70222 0.505 45.16230 ? 254 ARG A HG2  1 
ATOM   3565 H  HG2  B ARG A 1 231 ? -11.11213 -34.02697 11.41697 0.495 44.99144 ? 254 ARG A HG2  1 
ATOM   3566 H  HG3  A ARG A 1 231 ? -11.95128 -34.06323 11.42022 0.505 45.16230 ? 254 ARG A HG3  1 
ATOM   3567 H  HG3  B ARG A 1 231 ? -12.15356 -33.01669 10.76877 0.495 44.99144 ? 254 ARG A HG3  1 
ATOM   3568 H  HD2  A ARG A 1 231 ? -10.20441 -32.24873 10.16272 0.505 52.48506 ? 254 ARG A HD2  1 
ATOM   3569 H  HD2  B ARG A 1 231 ? -10.39073 -31.63657 10.07442 0.495 46.78465 ? 254 ARG A HD2  1 
ATOM   3570 H  HD3  A ARG A 1 231 ? -10.58688 -33.63734 9.49123  0.505 52.48506 ? 254 ARG A HD3  1 
ATOM   3571 H  HD3  B ARG A 1 231 ? -9.34479  -32.63389 10.73532 0.495 46.78465 ? 254 ARG A HD3  1 
ATOM   3572 H  HE   A ARG A 1 231 ? -12.70407 -32.08263 10.07353 0.505 54.96788 ? 254 ARG A HE   1 
ATOM   3573 H  HE   B ARG A 1 231 ? -10.57411 -33.01527 8.36351  0.495 55.09254 ? 254 ARG A HE   1 
ATOM   3574 H  HH11 A ARG A 1 231 ? -10.66836 -32.87927 7.57303  0.505 52.04499 ? 254 ARG A HH11 1 
ATOM   3575 H  HH11 B ARG A 1 231 ? -8.61977  -34.52900 10.58775 0.495 52.78660 ? 254 ARG A HH11 1 
ATOM   3576 H  HH12 A ARG A 1 231 ? -11.55943 -32.37561 6.49084  0.505 52.04499 ? 254 ARG A HH12 1 
ATOM   3577 H  HH12 B ARG A 1 231 ? -8.15146  -35.60016 9.66466  0.495 52.78660 ? 254 ARG A HH12 1 
ATOM   3578 H  HH21 A ARG A 1 231 ? -14.02050 -31.34389 8.41571  0.505 48.98796 ? 254 ARG A HH21 1 
ATOM   3579 H  HH21 B ARG A 1 231 ? -9.84592  -34.65034 7.00879  0.495 66.37817 ? 254 ARG A HH21 1 
ATOM   3580 H  HH22 A ARG A 1 231 ? -13.57850 -31.45103 6.99727  0.505 48.98796 ? 254 ARG A HH22 1 
ATOM   3581 H  HH22 B ARG A 1 231 ? -8.88826  -35.67425 7.51209  0.495 66.37817 ? 254 ARG A HH22 1 
ATOM   3582 N  N    . ALA A 1 232 ? -10.92110 -32.32873 15.53943 1.000 24.10958 ? 255 ALA A N    1 
ATOM   3583 C  CA   . ALA A 1 232 ? -10.48032 -31.57925 16.70230 1.000 20.16734 ? 255 ALA A CA   1 
ATOM   3584 C  C    . ALA A 1 232 ? -10.04866 -30.18919 16.25708 1.000 21.55839 ? 255 ALA A C    1 
ATOM   3585 O  O    . ALA A 1 232 ? -9.62448  -29.99812 15.11316 1.000 22.55199 ? 255 ALA A O    1 
ATOM   3586 C  CB   . ALA A 1 232 ? -9.31318  -32.27390 17.39199 1.000 20.22036 ? 255 ALA A CB   1 
ATOM   3587 H  H    . ALA A 1 232 ? -10.41443 -32.99402 15.33872 1.000 28.91141 ? 255 ALA A H    1 
ATOM   3588 H  HA   . ALA A 1 232 ? -11.20311 -31.51025 17.34551 1.000 24.18073 ? 255 ALA A HA   1 
ATOM   3589 H  HB1  . ALA A 1 232 ? -9.02130  -31.73180 18.14155 1.000 24.24435 ? 255 ALA A HB1  1 
ATOM   3590 H  HB2  . ALA A 1 232 ? -9.60475  -33.14388 17.70666 1.000 24.24435 ? 255 ALA A HB2  1 
ATOM   3591 H  HB3  . ALA A 1 232 ? -8.58759  -32.37805 16.75671 1.000 24.24435 ? 255 ALA A HB3  1 
ATOM   3592 N  N    . PRO A 1 233 ? -10.15406 -29.20247 17.13449 1.000 25.37150 ? 256 PRO A N    1 
ATOM   3593 C  CA   . PRO A 1 233 ? -9.88564  -27.82315 16.71578 1.000 17.92868 ? 256 PRO A CA   1 
ATOM   3594 C  C    . PRO A 1 233 ? -8.41088  -27.57704 16.43313 1.000 14.64794 ? 256 PRO A C    1 
ATOM   3595 O  O    . PRO A 1 233 ? -7.51221  -28.27090 16.91985 1.000 17.12400 ? 256 PRO A O    1 
ATOM   3596 C  CB   . PRO A 1 233 ? -10.36240 -26.96942 17.89339 1.000 29.08026 ? 256 PRO A CB   1 
ATOM   3597 C  CG   . PRO A 1 233 ? -10.72874 -27.89220 18.96422 1.000 26.86724 ? 256 PRO A CG   1 
ATOM   3598 C  CD   . PRO A 1 233 ? -10.77803 -29.29468 18.46854 1.000 23.96688 ? 256 PRO A CD   1 
ATOM   3599 H  HA   . PRO A 1 233 ? -10.40928 -27.61529 15.92616 1.000 21.49433 ? 256 PRO A HA   1 
ATOM   3600 H  HB2  . PRO A 1 233 ? -9.64362  -26.38424 18.17943 1.000 34.87623 ? 256 PRO A HB2  1 
ATOM   3601 H  HB3  . PRO A 1 233 ? -11.13000 -26.44301 17.62027 1.000 34.87623 ? 256 PRO A HB3  1 
ATOM   3602 H  HG2  . PRO A 1 233 ? -10.06619 -27.82067 19.66907 1.000 32.22061 ? 256 PRO A HG2  1 
ATOM   3603 H  HG3  . PRO A 1 233 ? -11.60145 -27.63702 19.30211 1.000 32.22061 ? 256 PRO A HG3  1 
ATOM   3604 H  HD2  . PRO A 1 233 ? -10.26999 -29.88401 19.04774 1.000 28.74018 ? 256 PRO A HD2  1 
ATOM   3605 H  HD3  . PRO A 1 233 ? -11.69446 -29.60528 18.40074 1.000 28.74018 ? 256 PRO A HD3  1 
ATOM   3606 N  N    . LEU A 1 234 ? -8.18624  -26.54797 15.62375 1.000 19.26389 ? 257 LEU A N    1 
ATOM   3607 C  CA   . LEU A 1 234 ? -6.87274  -26.03880 15.28932 1.000 14.98629 ? 257 LEU A CA   1 
ATOM   3608 C  C    . LEU A 1 234 ? -6.71709  -24.62431 15.83230 1.000 15.22589 ? 257 LEU A C    1 
ATOM   3609 O  O    . LEU A 1 234 ? -7.69398  -23.89648 16.00826 1.000 16.48619 ? 257 LEU A O    1 
ATOM   3610 C  CB   . LEU A 1 234 ? -6.71415  -26.03783 13.76267 1.000 16.56836 ? 257 LEU A CB   1 
ATOM   3611 C  CG   . LEU A 1 234 ? -7.11759  -27.26630 12.99737 1.000 19.51302 ? 257 LEU A CG   1 
ATOM   3612 C  CD1  . LEU A 1 234 ? -7.09247  -26.98138 11.49008 1.000 25.39018 ? 257 LEU A CD1  1 
ATOM   3613 C  CD2  . LEU A 1 234 ? -6.13150  -28.32966 13.30436 1.000 20.96575 ? 257 LEU A CD2  1 
ATOM   3614 H  H    . LEU A 1 234 ? -8.81640  -26.10802 15.23783 1.000 23.09658 ? 257 LEU A H    1 
ATOM   3615 H  HA   . LEU A 1 234 ? -6.17367  -26.58032 15.68802 1.000 17.96347 ? 257 LEU A HA   1 
ATOM   3616 H  HB2  . LEU A 1 234 ? -7.24865  -25.30741 13.41382 1.000 19.86195 ? 257 LEU A HB2  1 
ATOM   3617 H  HB3  . LEU A 1 234 ? -5.77643  -25.88595 13.56640 1.000 19.86195 ? 257 LEU A HB3  1 
ATOM   3618 H  HG   . LEU A 1 234 ? -8.01422  -27.54322 13.24284 1.000 23.39554 ? 257 LEU A HG   1 
ATOM   3619 H  HD11 . LEU A 1 234 ? -7.40617  -27.76673 11.01497 1.000 30.44813 ? 257 LEU A HD11 1 
ATOM   3620 H  HD12 . LEU A 1 234 ? -7.67247  -26.22710 11.30155 1.000 30.44813 ? 257 LEU A HD12 1 
ATOM   3621 H  HD13 . LEU A 1 234 ? -6.18325  -26.77439 11.22292 1.000 30.44813 ? 257 LEU A HD13 1 
ATOM   3622 H  HD21 . LEU A 1 234 ? -6.38374  -29.13960 12.83396 1.000 25.13882 ? 257 LEU A HD21 1 
ATOM   3623 H  HD22 . LEU A 1 234 ? -5.25277  -28.03875 13.01436 1.000 25.13882 ? 257 LEU A HD22 1 
ATOM   3624 H  HD23 . LEU A 1 234 ? -6.12777  -28.49026 14.26097 1.000 25.13882 ? 257 LEU A HD23 1 
ATOM   3625 N  N    . ILE A 1 235 ? -5.47834  -24.24896 16.11574 1.000 16.44605 ? 258 ILE A N    1 
ATOM   3626 C  CA   . ILE A 1 235 ? -5.08529  -22.85698 16.27675 1.000 15.65822 ? 258 ILE A CA   1 
ATOM   3627 C  C    . ILE A 1 235 ? -4.13308  -22.50686 15.14494 1.000 12.35008 ? 258 ILE A C    1 
ATOM   3628 O  O    . ILE A 1 235 ? -3.19070  -23.26105 14.86529 1.000 16.91018 ? 258 ILE A O    1 
ATOM   3629 C  CB   . ILE A 1 235 ? -4.38784  -22.62952 17.63455 1.000 17.37201 ? 258 ILE A CB   1 
ATOM   3630 C  CG1  . ILE A 1 235 ? -5.33150  -23.00121 18.77297 1.000 17.61876 ? 258 ILE A CG1  1 
ATOM   3631 C  CG2  . ILE A 1 235 ? -3.93109  -21.19767 17.77684 1.000 17.34755 ? 258 ILE A CG2  1 
ATOM   3632 C  CD1  . ILE A 1 235 ? -6.48835  -22.08918 18.93036 1.000 21.56730 ? 258 ILE A CD1  1 
ATOM   3633 H  H    . ILE A 1 235 ? -4.82709  -24.80030 16.22294 1.000 19.71517 ? 258 ILE A H    1 
ATOM   3634 H  HA   . ILE A 1 235 ? -5.87114  -22.29052 16.22713 1.000 18.76978 ? 258 ILE A HA   1 
ATOM   3635 H  HB   . ILE A 1 235 ? -3.60448  -23.20036 17.67197 1.000 20.82633 ? 258 ILE A HB   1 
ATOM   3636 H  HG12 . ILE A 1 235 ? -5.67989  -23.89135 18.60810 1.000 21.12243 ? 258 ILE A HG12 1 
ATOM   3637 H  HG13 . ILE A 1 235 ? -4.83283  -22.98894 19.60488 1.000 21.12243 ? 258 ILE A HG13 1 
ATOM   3638 H  HG21 . ILE A 1 235 ? -3.71398  -21.02636 18.70658 1.000 20.79698 ? 258 ILE A HG21 1 
ATOM   3639 H  HG22 . ILE A 1 235 ? -3.14663  -21.05992 17.22318 1.000 20.79698 ? 258 ILE A HG22 1 
ATOM   3640 H  HG23 . ILE A 1 235 ? -4.64602  -20.60815 17.49007 1.000 20.79698 ? 258 ILE A HG23 1 
ATOM   3641 H  HD11 . ILE A 1 235 ? -7.04101  -22.40361 19.66290 1.000 25.86067 ? 258 ILE A HD11 1 
ATOM   3642 H  HD12 . ILE A 1 235 ? -6.16245  -21.19583 19.12170 1.000 25.86067 ? 258 ILE A HD12 1 
ATOM   3643 H  HD13 . ILE A 1 235 ? -7.00139  -22.08487 18.10715 1.000 25.86067 ? 258 ILE A HD13 1 
ATOM   3644 N  N    . LEU A 1 236 ? -4.34774  -21.34205 14.52635 1.000 16.59238 ? 259 LEU A N    1 
ATOM   3645 C  CA   . LEU A 1 236 ? -3.49329  -20.94148 13.40944 1.000 17.63983 ? 259 LEU A CA   1 
ATOM   3646 C  C    . LEU A 1 236 ? -3.16644  -19.45675 13.52560 1.000 11.96388 ? 259 LEU A C    1 
ATOM   3647 O  O    . LEU A 1 236 ? -4.06845  -18.61880 13.62735 1.000 13.78155 ? 259 LEU A O    1 
ATOM   3648 C  CB   . LEU A 1 236 ? -4.16152  -21.24526 12.07100 1.000 14.25411 ? 259 LEU A CB   1 
ATOM   3649 C  CG   . LEU A 1 236 ? -3.37327  -20.74391 10.85285 1.000 21.15721 ? 259 LEU A CG   1 
ATOM   3650 C  CD1  . LEU A 1 236 ? -1.97683  -21.32413 10.77813 1.000 15.53914 ? 259 LEU A CD1  1 
ATOM   3651 C  CD2  . LEU A 1 236 ? -4.07742  -21.06273 9.54278  1.000 18.28616 ? 259 LEU A CD2  1 
ATOM   3652 H  H    . LEU A 1 236 ? -4.96717  -20.78195 14.73175 1.000 19.89078 ? 259 LEU A H    1 
ATOM   3653 H  HA   . LEU A 1 236 ? -2.65645  -21.43039 13.44893 1.000 21.14772 ? 259 LEU A HA   1 
ATOM   3654 H  HB2  . LEU A 1 236 ? -4.26037  -22.20632 11.98446 1.000 17.08485 ? 259 LEU A HB2  1 
ATOM   3655 H  HB3  . LEU A 1 236 ? -5.03290  -20.81938 12.05537 1.000 17.08485 ? 259 LEU A HB3  1 
ATOM   3656 H  HG   . LEU A 1 236 ? -3.31149  -19.78256 10.96642 1.000 25.36857 ? 259 LEU A HG   1 
ATOM   3657 H  HD11 . LEU A 1 236 ? -1.55120  -21.01867 9.96178  1.000 18.62688 ? 259 LEU A HD11 1 
ATOM   3658 H  HD12 . LEU A 1 236 ? -1.46874  -21.02451 11.54818 1.000 18.62688 ? 259 LEU A HD12 1 
ATOM   3659 H  HD13 . LEU A 1 236 ? -2.03673  -22.29227 10.77768 1.000 18.62688 ? 259 LEU A HD13 1 
ATOM   3660 H  HD21 . LEU A 1 236 ? -3.52983  -20.75007 8.80570  1.000 21.92331 ? 259 LEU A HD21 1 
ATOM   3661 H  HD22 . LEU A 1 236 ? -4.20350  -22.02227 9.47739  1.000 21.92331 ? 259 LEU A HD22 1 
ATOM   3662 H  HD23 . LEU A 1 236 ? -4.93750  -20.61441 9.52929  1.000 21.92331 ? 259 LEU A HD23 1 
ATOM   3663 N  N    . VAL A 1 237 ? -1.87014  -19.14812 13.50902 1.000 16.13359 ? 260 VAL A N    1 
ATOM   3664 C  CA   . VAL A 1 237 ? -1.36027  -17.78880 13.43506 1.000 14.63065 ? 260 VAL A CA   1 
ATOM   3665 C  C    . VAL A 1 237 ? -0.64715  -17.63827 12.10796 1.000 13.60685 ? 260 VAL A C    1 
ATOM   3666 O  O    . VAL A 1 237 ? 0.24247   -18.42698 11.79135 1.000 14.08708 ? 260 VAL A O    1 
ATOM   3667 C  CB   . VAL A 1 237 ? -0.41931  -17.45663 14.60781 1.000 13.73037 ? 260 VAL A CB   1 
ATOM   3668 C  CG1  . VAL A 1 237 ? 0.27086   -16.10385 14.38192 1.000 18.21212 ? 260 VAL A CG1  1 
ATOM   3669 C  CG2  . VAL A 1 237 ? -1.21305  -17.42740 15.90040 1.000 17.58627 ? 260 VAL A CG2  1 
ATOM   3670 H  H    . VAL A 1 237 ? -1.24456  -19.73737 13.54123 1.000 19.34023 ? 260 VAL A H    1 
ATOM   3671 H  HA   . VAL A 1 237 ? -2.10281  -17.16560 13.46902 1.000 17.53670 ? 260 VAL A HA   1 
ATOM   3672 H  HB   . VAL A 1 237 ? 0.26807   -18.13825 14.66959 1.000 16.45637 ? 260 VAL A HB   1 
ATOM   3673 H  HG11 . VAL A 1 237 ? 0.64823   -15.79777 15.22145 1.000 21.83447 ? 260 VAL A HG11 1 
ATOM   3674 H  HG12 . VAL A 1 237 ? 0.97470   -16.21442 13.72367 1.000 21.83447 ? 260 VAL A HG12 1 
ATOM   3675 H  HG13 . VAL A 1 237 ? -0.38448  -15.46463 14.06126 1.000 21.83447 ? 260 VAL A HG13 1 
ATOM   3676 H  HG21 . VAL A 1 237 ? -0.61022  -17.24058 16.63701 1.000 21.08345 ? 260 VAL A HG21 1 
ATOM   3677 H  HG22 . VAL A 1 237 ? -1.88785  -16.73313 15.84098 1.000 21.08345 ? 260 VAL A HG22 1 
ATOM   3678 H  HG23 . VAL A 1 237 ? -1.63674  -18.29023 16.03040 1.000 21.08345 ? 260 VAL A HG23 1 
ATOM   3679 N  N    . THR A 1 238 ? -1.06088  -16.63584 11.32718 1.000 15.78448 ? 261 THR A N    1 
ATOM   3680 C  CA   . THR A 1 238 ? -0.38549  -16.25893 10.09203 1.000 13.83231 ? 261 THR A CA   1 
ATOM   3681 C  C    . THR A 1 238 ? -0.05446  -14.77298 10.14989 1.000 13.41971 ? 261 THR A C    1 
ATOM   3682 O  O    . THR A 1 238 ? -0.96520  -13.93583 10.22114 1.000 14.73810 ? 261 THR A O    1 
ATOM   3683 C  CB   . THR A 1 238 ? -1.24125  -16.56343 8.85626  1.000 16.00321 ? 261 THR A CB   1 
ATOM   3684 O  OG1  . THR A 1 238 ? -2.46795  -15.84651 8.94085  1.000 17.79359 ? 261 THR A OG1  1 
ATOM   3685 C  CG2  . THR A 1 238 ? -1.52520  -18.07558 8.70799  1.000 14.57679 ? 261 THR A CG2  1 
ATOM   3686 H  H    . THR A 1 238 ? -1.74874  -16.14960 11.50046 1.000 18.92129 ? 261 THR A H    1 
ATOM   3687 H  HA   . THR A 1 238 ? 0.44021   -16.76280 10.01974 1.000 16.57870 ? 261 THR A HA   1 
ATOM   3688 H  HB   . THR A 1 238 ? -0.75510  -16.28761 8.06349  1.000 19.18377 ? 261 THR A HB   1 
ATOM   3689 H  HG1  . THR A 1 238 ? -2.31905  -15.01990 8.92867  1.000 21.33222 ? 261 THR A HG1  1 
ATOM   3690 H  HG21 . THR A 1 238 ? -2.07593  -18.23456 7.92548  1.000 17.47206 ? 261 THR A HG21 1 
ATOM   3691 H  HG22 . THR A 1 238 ? -0.69150  -18.56167 8.61022  1.000 17.47206 ? 261 THR A HG22 1 
ATOM   3692 H  HG23 . THR A 1 238 ? -1.99101  -18.40418 9.49281  1.000 17.47206 ? 261 THR A HG23 1 
ATOM   3693 N  N    . TYR A 1 239 ? 1.25684   -14.46324 10.11369 1.000 15.12868 ? 262 TYR A N    1 
ATOM   3694 C  CA   . TYR A 1 239 ? 1.79398   -13.11746 10.25085 1.000 15.48561 ? 262 TYR A CA   1 
ATOM   3695 C  C    . TYR A 1 239 ? 2.56347   -12.81855 8.97139  1.000 14.73216 ? 262 TYR A C    1 
ATOM   3696 O  O    . TYR A 1 239 ? 3.26838   -13.69333 8.43938  1.000 16.63844 ? 262 TYR A O    1 
ATOM   3697 C  CB   . TYR A 1 239 ? 2.70954   -12.98842 11.47426 1.000 14.82512 ? 262 TYR A CB   1 
ATOM   3698 C  CG   . TYR A 1 239 ? 2.00234   -12.76133 12.79722 1.000 18.16108 ? 262 TYR A CG   1 
ATOM   3699 C  CD1  . TYR A 1 239 ? 0.64530   -12.50959 12.85860 1.000 14.63095 ? 262 TYR A CD1  1 
ATOM   3700 C  CD2  . TYR A 1 239 ? 2.70711   -12.79027 13.96994 1.000 23.03153 ? 262 TYR A CD2  1 
ATOM   3701 C  CE1  . TYR A 1 239 ? 0.00674   -12.29294 14.08536 1.000 17.23552 ? 262 TYR A CE1  1 
ATOM   3702 C  CE2  . TYR A 1 239 ? 2.08417   -12.57379 15.18609 1.000 22.08541 ? 262 TYR A CE2  1 
ATOM   3703 C  CZ   . TYR A 1 239 ? 0.72736   -12.33235 15.22259 1.000 16.63599 ? 262 TYR A CZ   1 
ATOM   3704 O  OH   . TYR A 1 239 ? 0.12775   -12.07045 16.45673 1.000 20.72963 ? 262 TYR A OH   1 
ATOM   3705 H  H    . TYR A 1 239 ? 1.87435   -15.05186 10.00505 1.000 18.13433 ? 262 TYR A H    1 
ATOM   3706 H  HA   . TYR A 1 239 ? 1.08401   -12.46773 10.37205 1.000 18.56266 ? 262 TYR A HA   1 
ATOM   3707 H  HB2  . TYR A 1 239 ? 3.22367   -13.80665 11.55838 1.000 17.77006 ? 262 TYR A HB2  1 
ATOM   3708 H  HB3  . TYR A 1 239 ? 3.30470   -12.23579 11.33205 1.000 17.77006 ? 262 TYR A HB3  1 
ATOM   3709 H  HD1  . TYR A 1 239 ? 0.14842   -12.48368 12.07289 1.000 17.53706 ? 262 TYR A HD1  1 
ATOM   3710 H  HD2  . TYR A 1 239 ? 3.62152   -12.95853 13.94897 1.000 27.61776 ? 262 TYR A HD2  1 
ATOM   3711 H  HE1  . TYR A 1 239 ? -0.90718  -12.12326 14.11487 1.000 20.66255 ? 262 TYR A HE1  1 
ATOM   3712 H  HE2  . TYR A 1 239 ? 2.57767   -12.59104 15.97416 1.000 26.48242 ? 262 TYR A HE2  1 
ATOM   3713 H  HH   . TYR A 1 239 ? -0.63634  -11.74132 16.34083 1.000 24.85548 ? 262 TYR A HH   1 
ATOM   3714 N  N    . PHE A 1 240 ? 2.40331   -11.61913 8.44266  1.000 17.47775 ? 263 PHE A N    1 
ATOM   3715 C  CA   . PHE A 1 240 ? 3.07923   -11.28660 7.19552  1.000 17.78230 ? 263 PHE A CA   1 
ATOM   3716 C  C    . PHE A 1 240 ? 3.40914   -9.79471  7.17949  1.000 16.13024 ? 263 PHE A C    1 
ATOM   3717 O  O    . PHE A 1 240 ? 2.57211   -8.97470  7.55089  1.000 16.29380 ? 263 PHE A O    1 
ATOM   3718 C  CB   . PHE A 1 240 ? 2.19317   -11.66978 5.98348  1.000 16.08002 ? 263 PHE A CB   1 
ATOM   3719 C  CG   . PHE A 1 240 ? 2.85663   -11.40888 4.65203  1.000 15.52462 ? 263 PHE A CG   1 
ATOM   3720 C  CD1  . PHE A 1 240 ? 3.93650   -12.17201 4.24505  1.000 16.03493 ? 263 PHE A CD1  1 
ATOM   3721 C  CD2  . PHE A 1 240 ? 2.40303   -10.40160 3.82528  1.000 14.74931 ? 263 PHE A CD2  1 
ATOM   3722 C  CE1  . PHE A 1 240 ? 4.57252   -11.91585 3.05917  1.000 19.11506 ? 263 PHE A CE1  1 
ATOM   3723 C  CE2  . PHE A 1 240 ? 3.03363   -10.13342 2.61965  1.000 16.30932 ? 263 PHE A CE2  1 
ATOM   3724 C  CZ   . PHE A 1 240 ? 4.12418   -10.89523 2.23293  1.000 19.87017 ? 263 PHE A CZ   1 
ATOM   3725 H  H    A PHE A 1 240 ? 1.91957   -10.99163 8.77709  0.740 20.95322 ? 263 PHE A H    1 
ATOM   3726 H  H    B PHE A 1 240 ? 1.91957   -10.99163 8.77709  0.260 20.95322 ? 263 PHE A H    1 
ATOM   3727 H  HA   . PHE A 1 240 ? 3.91958   -11.76668 7.13029  1.000 21.31868 ? 263 PHE A HA   1 
ATOM   3728 H  HB2  . PHE A 1 240 ? 1.98631   -12.61617 6.03295  1.000 19.27595 ? 263 PHE A HB2  1 
ATOM   3729 H  HB3  . PHE A 1 240 ? 1.37528   -11.14928 6.01590  1.000 19.27595 ? 263 PHE A HB3  1 
ATOM   3730 H  HD1  . PHE A 1 240 ? 4.23477   -12.86865 4.78414  1.000 19.22183 ? 263 PHE A HD1  1 
ATOM   3731 H  HD2  . PHE A 1 240 ? 1.66505   -9.89612  4.07980  1.000 17.67910 ? 263 PHE A HD2  1 
ATOM   3732 H  HE1  . PHE A 1 240 ? 5.30703   -12.42755 2.80708  1.000 22.91800 ? 263 PHE A HE1  1 
ATOM   3733 H  HE2  . PHE A 1 240 ? 2.72617   -9.44607  2.07384  1.000 19.55111 ? 263 PHE A HE2  1 
ATOM   3734 H  HZ   . PHE A 1 240 ? 4.55263   -10.72385 1.42549  1.000 23.82413 ? 263 PHE A HZ   1 
ATOM   3735 N  N    . THR A 1 241 ? 4.60942   -9.45868  6.70018  1.000 17.28859 ? 264 THR A N    1 
ATOM   3736 C  CA   . THR A 1 241 ? 5.03651   -8.06151  6.58363  1.000 17.66246 ? 264 THR A CA   1 
ATOM   3737 C  C    . THR A 1 241 ? 6.03102   -7.92595  5.43002  1.000 19.40916 ? 264 THR A C    1 
ATOM   3738 O  O    . THR A 1 241 ? 6.63621   -8.90414  4.98476  1.000 18.84344 ? 264 THR A O    1 
ATOM   3739 C  CB   . THR A 1 241 ? 5.64567   -7.56187  7.91308  1.000 20.27550 ? 264 THR A CB   1 
ATOM   3740 O  OG1  . THR A 1 241 ? 5.83578   -6.13119  7.86365  1.000 21.40058 ? 264 THR A OG1  1 
ATOM   3741 C  CG2  . THR A 1 241 ? 6.95513   -8.27010  8.16366  1.000 22.62669 ? 264 THR A CG2  1 
ATOM   3742 H  H    . THR A 1 241 ? 5.19901   -10.02528 6.43382  1.000 20.72623 ? 264 THR A H    1 
ATOM   3743 H  HA   . THR A 1 241 ? 4.27434   -7.50192  6.36719  1.000 21.17487 ? 264 THR A HA   1 
ATOM   3744 H  HB   . THR A 1 241 ? 5.04903   -7.75559  8.65294  1.000 24.31052 ? 264 THR A HB   1 
ATOM   3745 H  HG1  . THR A 1 241 ? 5.10108   -5.74836  7.72492  1.000 25.66061 ? 264 THR A HG1  1 
ATOM   3746 H  HG21 . THR A 1 241 ? 7.22723   -8.14764  9.08662  1.000 27.13195 ? 264 THR A HG21 1 
ATOM   3747 H  HG22 . THR A 1 241 ? 6.85815   -9.21899  7.98731  1.000 27.13195 ? 264 THR A HG22 1 
ATOM   3748 H  HG23 . THR A 1 241 ? 7.64332   -7.91059  7.58224  1.000 27.13195 ? 264 THR A HG23 1 
ATOM   3749 N  N    . GLN A 1 242 ? 6.18553   -6.70580  4.93345  1.000 18.61877 ? 265 GLN A N    1 
ATOM   3750 C  CA   . GLN A 1 242 ? 6.80781   -6.45193  3.64515  1.000 15.43385 ? 265 GLN A CA   1 
ATOM   3751 C  C    . GLN A 1 242 ? 7.89811   -5.40191  3.74124  1.000 16.77430 ? 265 GLN A C    1 
ATOM   3752 O  O    . GLN A 1 242 ? 8.01749   -4.70767  4.75351  1.000 22.41415 ? 265 GLN A O    1 
ATOM   3753 C  CB   . GLN A 1 242 ? 5.73867   -6.02263  2.62711  1.000 19.87872 ? 265 GLN A CB   1 
ATOM   3754 C  CG   . GLN A 1 242 ? 4.74383   -7.14908  2.37428  1.000 21.92499 ? 265 GLN A CG   1 
ATOM   3755 C  CD   . GLN A 1 242 ? 3.65092   -6.76067  1.42912  1.000 17.91974 ? 265 GLN A CD   1 
ATOM   3756 O  OE1  . GLN A 1 242 ? 3.85808   -6.68469  0.21398  1.000 20.61354 ? 265 GLN A OE1  1 
ATOM   3757 N  NE2  . GLN A 1 242 ? 2.46903   -6.48095  1.98321  1.000 20.13128 ? 265 GLN A NE2  1 
ATOM   3758 H  H    . GLN A 1 242 ? 5.92970   -5.99134  5.33805  1.000 22.32244 ? 265 GLN A H    1 
ATOM   3759 H  HA   . GLN A 1 242 ? 7.23901   -7.26640  3.34248  1.000 18.50054 ? 265 GLN A HA   1 
ATOM   3760 H  HB2  . GLN A 1 242 ? 5.25471   -5.25577  2.97151  1.000 23.83438 ? 265 GLN A HB2  1 
ATOM   3761 H  HB3  . GLN A 1 242 ? 6.16633   -5.79497  1.78676  1.000 23.83438 ? 265 GLN A HB3  1 
ATOM   3762 H  HG2  . GLN A 1 242 ? 5.21488   -7.90602  1.99211  1.000 26.28991 ? 265 GLN A HG2  1 
ATOM   3763 H  HG3  . GLN A 1 242 ? 4.33484   -7.40355  3.21623  1.000 26.28991 ? 265 GLN A HG3  1 
ATOM   3764 H  HE21 . GLN A 1 242 ? 2.37172   -6.52980  2.83629  1.000 24.13745 ? 265 GLN A HE21 1 
ATOM   3765 H  HE22 . GLN A 1 242 ? 1.80496   -6.25190  1.48708  1.000 24.13745 ? 265 GLN A HE22 1 
ATOM   3766 N  N    . PRO A 1 243 ? 8.73925   -5.28513  2.70112  1.000 20.74131 ? 266 PRO A N    1 
ATOM   3767 C  CA   . PRO A 1 243 ? 9.89271   -4.37709  2.77270  1.000 25.29484 ? 266 PRO A CA   1 
ATOM   3768 C  C    . PRO A 1 243 ? 9.56265   -2.89935  2.60943  1.000 21.40740 ? 266 PRO A C    1 
ATOM   3769 O  O    . PRO A 1 243 ? 10.33405  -2.04283  3.06368  1.000 25.67665 ? 266 PRO A O    1 
ATOM   3770 C  CB   . PRO A 1 243 ? 10.80787  -4.84311  1.61775  1.000 19.83306 ? 266 PRO A CB   1 
ATOM   3771 C  CG   . PRO A 1 243 ? 10.23688  -6.06666  1.09302  1.000 22.78396 ? 266 PRO A CG   1 
ATOM   3772 C  CD   . PRO A 1 243 ? 8.84658   -6.26436  1.60731  1.000 23.81439 ? 266 PRO A CD   1 
ATOM   3773 H  HA   . PRO A 1 243 ? 10.32056  -4.51335  3.63252  1.000 30.33373 ? 266 PRO A HA   1 
ATOM   3774 H  HB2  . PRO A 1 243 ? 10.83391  -4.15840  0.93117  1.000 23.77959 ? 266 PRO A HB2  1 
ATOM   3775 H  HB3  . PRO A 1 243 ? 11.70120  -5.00422  1.95967  1.000 23.77959 ? 266 PRO A HB3  1 
ATOM   3776 H  HG2  . PRO A 1 243 ? 10.22046  -6.00734  0.12497  1.000 27.32067 ? 266 PRO A HG2  1 
ATOM   3777 H  HG3  . PRO A 1 243 ? 10.79528  -6.80972  1.37044  1.000 27.32067 ? 266 PRO A HG3  1 
ATOM   3778 H  HD2  . PRO A 1 243 ? 8.19379   -6.07888  0.91424  1.000 28.55719 ? 266 PRO A HD2  1 
ATOM   3779 H  HD3  . PRO A 1 243 ? 8.72847   -7.16740  1.94120  1.000 28.55719 ? 266 PRO A HD3  1 
ATOM   3780 N  N    . GLN A 1 244 ? 8.45892   -2.57857  1.92228  1.000 19.46615 ? 267 GLN A N    1 
ATOM   3781 C  CA   . GLN A 1 244 ? 8.19223   -1.17903  1.57771  1.000 18.23786 ? 267 GLN A CA   1 
ATOM   3782 C  C    . GLN A 1 244 ? 7.25567   -0.53969  2.59495  1.000 21.06541 ? 267 GLN A C    1 
ATOM   3783 O  O    . GLN A 1 244 ? 6.24511   -1.14952  2.96062  1.000 19.21750 ? 267 GLN A O    1 
ATOM   3784 C  CB   . GLN A 1 244 ? 7.54269   -1.07473  0.20073  1.000 19.66135 ? 267 GLN A CB   1 
ATOM   3785 C  CG   . GLN A 1 244 ? 8.28819   -1.80579  -0.93816 1.000 21.22726 ? 267 GLN A CG   1 
ATOM   3786 C  CD   . GLN A 1 244 ? 7.87626   -3.25884  -1.10539 1.000 20.87885 ? 267 GLN A CD   1 
ATOM   3787 O  OE1  . GLN A 1 244 ? 7.12630   -3.80066  -0.32257 1.000 27.94801 ? 267 GLN A OE1  1 
ATOM   3788 N  NE2  . GLN A 1 244 ? 8.32719   -3.87386  -2.20050 1.000 23.65636 ? 267 GLN A NE2  1 
ATOM   3789 H  H    . GLN A 1 244 ? 7.86494   -3.13841  1.65142  1.000 23.33930 ? 267 GLN A H    1 
ATOM   3790 H  HA   . GLN A 1 244 ? 9.03084   -0.69166  1.56809  1.000 21.86535 ? 267 GLN A HA   1 
ATOM   3791 H  HB2  . GLN A 1 244 ? 6.65144   -1.45394  0.25353  1.000 23.57354 ? 267 GLN A HB2  1 
ATOM   3792 H  HB3  . GLN A 1 244 ? 7.49044   -0.13718  -0.04250 1.000 23.57354 ? 267 GLN A HB3  1 
ATOM   3793 H  HG2  . GLN A 1 244 ? 8.10633   -1.34878  -1.77420 1.000 25.45263 ? 267 GLN A HG2  1 
ATOM   3794 H  HG3  . GLN A 1 244 ? 9.23969   -1.78790  -0.75044 1.000 25.45263 ? 267 GLN A HG3  1 
ATOM   3795 H  HE21 . GLN A 1 244 ? 8.82036   -3.44711  -2.76109 1.000 28.36755 ? 267 GLN A HE21 1 
ATOM   3796 H  HE22 . GLN A 1 244 ? 8.12462   -4.69697  -2.34564 1.000 28.36755 ? 267 GLN A HE22 1 
ATOM   3797 N  N    . PRO A 1 245 ? 7.53326   0.69912   3.03310  1.000 20.56257 ? 268 PRO A N    1 
ATOM   3798 C  CA   . PRO A 1 245 ? 6.64165   1.31796   4.02342  1.000 18.82068 ? 268 PRO A CA   1 
ATOM   3799 C  C    . PRO A 1 245 ? 5.20081   1.39575   3.57866  1.000 20.58662 ? 268 PRO A C    1 
ATOM   3800 O  O    . PRO A 1 245 ? 4.31357   1.23790   4.41507  1.000 21.98412 ? 268 PRO A O    1 
ATOM   3801 C  CB   . PRO A 1 245 ? 7.23700   2.72299   4.21492  1.000 26.67016 ? 268 PRO A CB   1 
ATOM   3802 C  CG   . PRO A 1 245 ? 8.61966   2.61762   3.77532  1.000 22.30907 ? 268 PRO A CG   1 
ATOM   3803 C  CD   . PRO A 1 245 ? 8.68047   1.57244   2.72515  1.000 19.50020 ? 268 PRO A CD   1 
ATOM   3804 H  HA   . PRO A 1 245 ? 6.70013   0.82011   4.85386  1.000 22.56474 ? 268 PRO A HA   1 
ATOM   3805 H  HB2  . PRO A 1 245 ? 6.74960   3.36329   3.67330  1.000 31.98412 ? 268 PRO A HB2  1 
ATOM   3806 H  HB3  . PRO A 1 245 ? 7.18963   2.97554   5.15027  1.000 31.98412 ? 268 PRO A HB3  1 
ATOM   3807 H  HG2  . PRO A 1 245 ? 8.90709   3.47200   3.41711  1.000 26.75081 ? 268 PRO A HG2  1 
ATOM   3808 H  HG3  . PRO A 1 245 ? 9.17682   2.36980   4.52968  1.000 26.75081 ? 268 PRO A HG3  1 
ATOM   3809 H  HD2  . PRO A 1 245 ? 8.58597   1.96554   1.84342  1.000 23.38016 ? 268 PRO A HD2  1 
ATOM   3810 H  HD3  . PRO A 1 245 ? 9.51316   1.07799   2.78044  1.000 23.38016 ? 268 PRO A HD3  1 
ATOM   3811 N  N    . LYS A 1 246 ? 4.92858   1.65251   2.29424  1.000 19.31578 ? 269 LYS A N    1 
ATOM   3812 C  CA   . LYS A 1 246 ? 3.55668   1.81333   1.83634  1.000 21.22416 ? 269 LYS A CA   1 
ATOM   3813 C  C    . LYS A 1 246 ? 3.05394   0.60313   1.05482  1.000 20.53543 ? 269 LYS A C    1 
ATOM   3814 O  O    . LYS A 1 246 ? 2.11197   0.72280   0.25428  1.000 22.30167 ? 269 LYS A O    1 
ATOM   3815 C  CB   . LYS A 1 246 ? 3.42553   3.08737   1.00409  1.000 24.46869 ? 269 LYS A CB   1 
ATOM   3816 C  CG   . LYS A 1 246 ? 3.83888   4.35509   1.72785  1.000 27.22950 ? 269 LYS A CG   1 
ATOM   3817 C  CD   . LYS A 1 246 ? 3.56661   5.60202   0.85945  1.000 41.19587 ? 269 LYS A CD   1 
ATOM   3818 C  CE   . LYS A 1 246 ? 4.05286   6.87884   1.52129  1.000 52.37436 ? 269 LYS A CE   1 
ATOM   3819 N  NZ   . LYS A 1 246 ? 4.06957   8.03636   0.57834  1.000 65.33626 ? 269 LYS A NZ   1 
ATOM   3820 H  H    . LYS A 1 246 ? 5.52263   1.73630   1.67806  1.000 23.15886 ? 269 LYS A H    1 
ATOM   3821 H  HA   . LYS A 1 246 ? 2.98393   1.90637   2.61365  1.000 25.44891 ? 269 LYS A HA   1 
ATOM   3822 H  HB2  . LYS A 1 246 ? 3.98714   3.00220   0.21781  1.000 29.34234 ? 269 LYS A HB2  1 
ATOM   3823 H  HB3  . LYS A 1 246 ? 2.49790   3.18982   0.73970  1.000 29.34234 ? 269 LYS A HB3  1 
ATOM   3824 H  HG2  . LYS A 1 246 ? 3.33181   4.43743   2.55065  1.000 32.65532 ? 269 LYS A HG2  1 
ATOM   3825 H  HG3  . LYS A 1 246 ? 4.78794   4.31976   1.92516  1.000 32.65532 ? 269 LYS A HG3  1 
ATOM   3826 H  HD2  . LYS A 1 246 ? 4.02802   5.50680   0.01155  1.000 49.41497 ? 269 LYS A HD2  1 
ATOM   3827 H  HD3  . LYS A 1 246 ? 2.61170   5.68407   0.71013  1.000 49.41497 ? 269 LYS A HD3  1 
ATOM   3828 H  HE2  . LYS A 1 246 ? 3.46258   7.09931   2.25876  1.000 62.82915 ? 269 LYS A HE2  1 
ATOM   3829 H  HE3  . LYS A 1 246 ? 4.95598   6.74336   1.84828  1.000 62.82915 ? 269 LYS A HE3  1 
ATOM   3830 H  HZ1  . LYS A 1 246 ? 4.37005   8.76353   0.99431  1.000 78.38344 ? 269 LYS A HZ1  1 
ATOM   3831 H  HZ2  . LYS A 1 246 ? 4.60144   7.85838   -0.11271 1.000 78.38344 ? 269 LYS A HZ2  1 
ATOM   3832 H  HZ3  . LYS A 1 246 ? 3.24744   8.19513   0.27668  1.000 78.38344 ? 269 LYS A HZ3  1 
ATOM   3833 N  N    . ALA A 1 247 ? 3.65669   -0.55969  1.27153  1.000 18.51337 ? 270 ALA A N    1 
ATOM   3834 C  CA   . ALA A 1 247 ? 3.16546   -1.77227  0.63326  1.000 21.34232 ? 270 ALA A CA   1 
ATOM   3835 C  C    . ALA A 1 247 ? 1.69202   -1.97808  0.94518  1.000 25.21025 ? 270 ALA A C    1 
ATOM   3836 O  O    . ALA A 1 247 ? 1.21890   -1.67000  2.04034  1.000 21.34815 ? 270 ALA A O    1 
ATOM   3837 C  CB   . ALA A 1 247 ? 3.96415   -3.00366  1.10701  1.000 21.92638 ? 270 ALA A CB   1 
ATOM   3838 H  H    . ALA A 1 247 ? 4.34310   -0.67202  1.77732  1.000 22.19597 ? 270 ALA A H    1 
ATOM   3839 H  HA   . ALA A 1 247 ? 3.27614   -1.68825  -0.32673 1.000 25.59071 ? 270 ALA A HA   1 
ATOM   3840 H  HB1  . ALA A 1 247 ? 3.61332   -3.79508  0.66944  1.000 26.29158 ? 270 ALA A HB1  1 
ATOM   3841 H  HB2  . ALA A 1 247 ? 4.89796   -2.88324  0.87377  1.000 26.29158 ? 270 ALA A HB2  1 
ATOM   3842 H  HB3  . ALA A 1 247 ? 3.87180   -3.08906  2.06881  1.000 26.29158 ? 270 ALA A HB3  1 
ATOM   3843 N  N    . GLU A 1 248 ? 0.96398   -2.53334  -0.01792 1.000 24.24778 ? 271 GLU A N    1 
ATOM   3844 C  CA   . GLU A 1 248 ? -0.43910  -2.81961  0.21856  1.000 22.62194 ? 271 GLU A CA   1 
ATOM   3845 C  C    . GLU A 1 248 ? -0.63732  -4.15333  0.93846  1.000 21.30334 ? 271 GLU A C    1 
ATOM   3846 O  O    . GLU A 1 248 ? 0.21870   -5.02901  0.94730  1.000 21.61007 ? 271 GLU A O    1 
ATOM   3847 C  CB   . GLU A 1 248 ? -1.19633  -2.80907  -1.10734 1.000 29.48065 ? 271 GLU A CB   1 
ATOM   3848 C  CG   . GLU A 1 248 ? -1.10565  -1.45635  -1.80979 1.000 51.58760 ? 271 GLU A CG   1 
ATOM   3849 C  CD   . GLU A 1 248 ? -2.04020  -1.33664  -2.98801 1.000 61.36597 ? 271 GLU A CD   1 
ATOM   3850 O  OE1  . GLU A 1 248 ? -3.09208  -2.01195  -2.98709 1.000 63.14709 ? 271 GLU A OE1  1 
ATOM   3851 O  OE2  . GLU A 1 248 ? -1.71936  -0.56524  -3.91289 1.000 77.15217 ? 271 GLU A OE2  1 
ATOM   3852 H  H    . GLU A 1 248 ? 1.25535   -2.74775  -0.79813 1.000 29.07726 ? 271 GLU A H    1 
ATOM   3853 H  HA   . GLU A 1 248 ? -0.81049  -2.13561  0.79745  1.000 27.12625 ? 271 GLU A HA   1 
ATOM   3854 H  HB2  . GLU A 1 248 ? -0.81829  -3.48183  -1.69504 1.000 35.35669 ? 271 GLU A HB2  1 
ATOM   3855 H  HB3  . GLU A 1 248 ? -2.13223  -3.00210  -0.94083 1.000 35.35669 ? 271 GLU A HB3  1 
ATOM   3856 H  HG2  . GLU A 1 248 ? -1.33252  -0.75725  -1.17679 1.000 61.88504 ? 271 GLU A HG2  1 
ATOM   3857 H  HG3  . GLU A 1 248 ? -0.19998  -1.32986  -2.13329 1.000 61.88504 ? 271 GLU A HG3  1 
ATOM   3858 N  N    . SER A 1 249 ? -1.78000  -4.27645  1.59782  1.000 22.37698 ? 272 SER A N    1 
ATOM   3859 C  CA   . SER A 1 249 ? -2.10141  -5.50884  2.29943  1.000 22.72429 ? 272 SER A CA   1 
ATOM   3860 C  C    . SER A 1 249 ? -2.12495  -6.71434  1.36168  1.000 22.64586 ? 272 SER A C    1 
ATOM   3861 O  O    . SER A 1 249 ? -2.45461  -6.60481  0.18567  1.000 22.85176 ? 272 SER A O    1 
ATOM   3862 C  CB   . SER A 1 249 ? -3.47231  -5.37589  2.97933  1.000 40.18657 ? 272 SER A CB   1 
ATOM   3863 O  OG   . SER A 1 249 ? -3.36310  -4.63110  4.18021  1.000 51.93869 ? 272 SER A OG   1 
ATOM   3864 H  H    . SER A 1 249 ? -2.38266  -3.66555  1.65434  1.000 26.83230 ? 272 SER A H    1 
ATOM   3865 H  HA   . SER A 1 249 ? -1.41684  -5.66875  2.96777  1.000 27.24906 ? 272 SER A HA   1 
ATOM   3866 H  HB2  . SER A 1 249 ? -4.08126  -4.91951  2.37783  1.000 48.20380 ? 272 SER A HB2  1 
ATOM   3867 H  HB3  . SER A 1 249 ? -3.81088  -6.26122  3.18537  1.000 48.20380 ? 272 SER A HB3  1 
ATOM   3868 H  HG   . SER A 1 249 ? -3.13036  -3.84237  4.00894  1.000 62.30635 ? 272 SER A HG   1 
ATOM   3869 N  N    . ARG A 1 250 ? -1.77506  -7.87687  1.91366  1.000 19.72941 ? 273 ARG A N    1 
ATOM   3870 C  CA   . ARG A 1 250 ? -1.74858  -9.13376  1.16457  1.000 20.80892 ? 273 ARG A CA   1 
ATOM   3871 C  C    . ARG A 1 250 ? -2.50064  -10.20527 1.95639  1.000 20.33794 ? 273 ARG A C    1 
ATOM   3872 O  O    . ARG A 1 250 ? -1.90743  -11.16314 2.47914  1.000 19.44572 ? 273 ARG A O    1 
ATOM   3873 C  CB   . ARG A 1 250 ? -0.32036  -9.57161  0.87160  1.000 22.54078 ? 273 ARG A CB   1 
ATOM   3874 C  CG   . ARG A 1 250 ? 0.41152   -8.67200  -0.10399 1.000 25.52350 ? 273 ARG A CG   1 
ATOM   3875 C  CD   . ARG A 1 250 ? -0.20687  -8.70297  -1.49496 1.000 26.69195 ? 273 ARG A CD   1 
ATOM   3876 N  NE   . ARG A 1 250 ? -0.26647  -10.04649 -2.05975 1.000 26.31109 ? 273 ARG A NE   1 
ATOM   3877 C  CZ   . ARG A 1 250 ? 0.72741   -10.62544 -2.71752 1.000 35.86630 ? 273 ARG A CZ   1 
ATOM   3878 N  NH1  . ARG A 1 250 ? 1.87796   -10.00125 -2.92271 1.000 29.17257 ? 273 ARG A NH1  1 
ATOM   3879 N  NH2  . ARG A 1 250 ? 0.56216   -11.85935 -3.18440 1.000 30.94050 ? 273 ARG A NH2  1 
ATOM   3880 H  H    . ARG A 1 250 ? -1.54428  -7.96405  2.73752  1.000 23.65521 ? 273 ARG A H    1 
ATOM   3881 H  HA   . ARG A 1 250 ? -2.21252  -8.99685  0.32380  1.000 24.95062 ? 273 ARG A HA   1 
ATOM   3882 H  HB2  . ARG A 1 250 ? 0.18035   -9.57538  1.70237  1.000 27.02885 ? 273 ARG A HB2  1 
ATOM   3883 H  HB3  . ARG A 1 250 ? -0.34034  -10.46412 0.49224  1.000 27.02885 ? 273 ARG A HB3  1 
ATOM   3884 H  HG2  . ARG A 1 250 ? 0.37902   -7.75828  0.21997  1.000 30.60812 ? 273 ARG A HG2  1 
ATOM   3885 H  HG3  . ARG A 1 250 ? 1.33317   -8.96540  -0.17734 1.000 30.60812 ? 273 ARG A HG3  1 
ATOM   3886 H  HD2  . ARG A 1 250 ? -1.11239  -8.35874  -1.44567 1.000 32.01026 ? 273 ARG A HD2  1 
ATOM   3887 H  HD3  . ARG A 1 250 ? 0.32565   -8.15185  -2.08959 1.000 32.01026 ? 273 ARG A HD3  1 
ATOM   3888 H  HE   . ARG A 1 250 ? -0.99494  -10.49238 -1.95916 1.000 31.55322 ? 273 ARG A HE   1 
ATOM   3889 H  HH11 . ARG A 1 250 ? 1.99242   -9.20208  -2.62637 1.000 34.98701 ? 273 ARG A HH11 1 
ATOM   3890 H  HH12 . ARG A 1 250 ? 2.51030   -10.39527 -3.35224 1.000 34.98701 ? 273 ARG A HH12 1 
ATOM   3891 H  HH21 . ARG A 1 250 ? -0.18231  -12.27087 -3.05784 1.000 37.10852 ? 273 ARG A HH21 1 
ATOM   3892 H  HH22 . ARG A 1 250 ? 1.19973   -12.24593 -3.61294 1.000 37.10852 ? 273 ARG A HH22 1 
ATOM   3893 N  N    . ARG A 1 251 ? -3.81463  -10.02482 2.09390  1.000 19.66413 ? 274 ARG A N    1 
ATOM   3894 C  CA   . ARG A 1 251 ? -4.58949  -11.03642 2.79785  1.000 17.21407 ? 274 ARG A CA   1 
ATOM   3895 C  C    . ARG A 1 251 ? -4.55077  -12.37123 2.05955  1.000 22.05938 ? 274 ARG A C    1 
ATOM   3896 O  O    . ARG A 1 251 ? -4.67088  -13.42777 2.67888  1.000 18.24901 ? 274 ARG A O    1 
ATOM   3897 C  CB   . ARG A 1 251 ? -6.03458  -10.56165 2.97663  1.000 19.90921 ? 274 ARG A CB   1 
ATOM   3898 C  CG   . ARG A 1 251 ? -6.11799  -9.31952  3.88458  1.000 20.52801 ? 274 ARG A CG   1 
ATOM   3899 C  CD   . ARG A 1 251 ? -7.44176  -8.64606  3.88854  1.000 32.61863 ? 274 ARG A CD   1 
ATOM   3900 N  NE   . ARG A 1 251 ? -7.30813  -7.47154  4.73965  1.000 32.45876 ? 274 ARG A NE   1 
ATOM   3901 C  CZ   . ARG A 1 251 ? -7.01332  -6.25612  4.30556  1.000 43.51960 ? 274 ARG A CZ   1 
ATOM   3902 N  NH1  . ARG A 1 251 ? -7.02744  -5.95754  3.01075  1.000 36.42836 ? 274 ARG A NH1  1 
ATOM   3903 N  NH2  . ARG A 1 251 ? -6.69787  -5.31647  5.19201  1.000 36.27933 ? 274 ARG A NH2  1 
ATOM   3904 H  H    . ARG A 1 251 ? -4.26143  -9.35146  1.79971  1.000 23.57688 ? 274 ARG A H    1 
ATOM   3905 H  HA   . ARG A 1 251 ? -4.21164  -11.16901 3.68133  1.000 20.63681 ? 274 ARG A HA   1 
ATOM   3906 H  HB2  . ARG A 1 251 ? -6.40496  -10.33136 2.11021  1.000 23.87097 ? 274 ARG A HB2  1 
ATOM   3907 H  HB3  . ARG A 1 251 ? -6.55643  -11.27149 3.38245  1.000 23.87097 ? 274 ARG A HB3  1 
ATOM   3908 H  HG2  . ARG A 1 251 ? -5.92477  -9.58881  4.79620  1.000 24.61353 ? 274 ARG A HG2  1 
ATOM   3909 H  HG3  . ARG A 1 251 ? -5.46176  -8.67157  3.58389  1.000 24.61353 ? 274 ARG A HG3  1 
ATOM   3910 H  HD2  . ARG A 1 251 ? -7.68573  -8.37136  2.99081  1.000 39.12227 ? 274 ARG A HD2  1 
ATOM   3911 H  HD3  . ARG A 1 251 ? -8.12148  -9.23529  4.25143  1.000 39.12227 ? 274 ARG A HD3  1 
ATOM   3912 H  HE   . ARG A 1 251 ? -7.42944  -7.57508  5.58473  1.000 38.93043 ? 274 ARG A HE   1 
ATOM   3913 H  HH11 . ARG A 1 251 ? -7.23152  -6.56061  2.43260  1.000 43.69395 ? 274 ARG A HH11 1 
ATOM   3914 H  HH12 . ARG A 1 251 ? -6.83251  -5.16123  2.75094  1.000 43.69395 ? 274 ARG A HH12 1 
ATOM   3915 H  HH21 . ARG A 1 251 ? -6.68781  -5.50322  6.03143  1.000 43.51512 ? 274 ARG A HH21 1 
ATOM   3916 H  HH22 . ARG A 1 251 ? -6.50391  -4.52202  4.92589  1.000 43.51512 ? 274 ARG A HH22 1 
ATOM   3917 N  N    . ASP A 1 252 ? -4.36601  -12.34140 0.73348  1.000 17.93626 ? 275 ASP A N    1 
ATOM   3918 C  CA   . ASP A 1 252 ? -4.29674  -13.58484 -0.02742 1.000 21.25832 ? 275 ASP A CA   1 
ATOM   3919 C  C    . ASP A 1 252 ? -3.12310  -14.44993 0.40019  1.000 22.53077 ? 275 ASP A C    1 
ATOM   3920 O  O    . ASP A 1 252 ? -3.18336  -15.68832 0.30262  1.000 17.26591 ? 275 ASP A O    1 
ATOM   3921 C  CB   . ASP A 1 252 ? -4.15936  -13.25437 -1.51311 1.000 20.40466 ? 275 ASP A CB   1 
ATOM   3922 C  CG   . ASP A 1 252 ? -2.90001  -12.44448 -1.80326 1.000 28.53194 ? 275 ASP A CG   1 
ATOM   3923 O  OD1  . ASP A 1 252 ? -2.76221  -11.33473 -1.25640 1.000 26.84691 ? 275 ASP A OD1  1 
ATOM   3924 O  OD2  . ASP A 1 252 ? -2.02059  -12.92220 -2.56052 1.000 31.91617 ? 275 ASP A OD2  1 
ATOM   3925 H  H    . ASP A 1 252 ? -4.27996  -11.62659 0.26313  1.000 21.50344 ? 275 ASP A H    1 
ATOM   3926 H  HA   . ASP A 1 252 ? -5.11321  -14.08676 0.12213  1.000 25.48991 ? 275 ASP A HA   1 
ATOM   3927 H  HB2  . ASP A 1 252 ? -4.11284  -14.07968 -2.02066 1.000 24.46551 ? 275 ASP A HB2  1 
ATOM   3928 H  HB3  . ASP A 1 252 ? -4.92697  -12.73344 -1.79649 1.000 24.46551 ? 275 ASP A HB3  1 
ATOM   3929 N  N    . VAL A 1 253 ? -2.03923  -13.82144 0.87054  1.000 18.81881 ? 276 VAL A N    1 
ATOM   3930 C  CA   . VAL A 1 253 ? -0.90741  -14.58121 1.40060  1.000 21.00003 ? 276 VAL A CA   1 
ATOM   3931 C  C    . VAL A 1 253 ? -1.31321  -15.37076 2.64500  1.000 22.09118 ? 276 VAL A C    1 
ATOM   3932 O  O    . VAL A 1 253 ? -0.95007  -16.54675 2.80931  1.000 18.46506 ? 276 VAL A O    1 
ATOM   3933 C  CB   . VAL A 1 253 ? 0.27323   -13.63113 1.66589  1.000 21.40363 ? 276 VAL A CB   1 
ATOM   3934 C  CG1  . VAL A 1 253 ? 1.37799   -14.34988 2.43382  1.000 20.87458 ? 276 VAL A CG1  1 
ATOM   3935 C  CG2  . VAL A 1 253 ? 0.79958   -13.08730 0.33469  1.000 22.70788 ? 276 VAL A CG2  1 
ATOM   3936 H  H    . VAL A 1 253 ? -1.93737  -12.96778 0.89290  1.000 22.56249 ? 276 VAL A H    1 
ATOM   3937 H  HA   . VAL A 1 253 ? -0.62662  -15.23140 0.73778  1.000 25.17995 ? 276 VAL A HA   1 
ATOM   3938 H  HB   . VAL A 1 253 ? -0.02502  -12.88606 2.21070  1.000 25.66427 ? 276 VAL A HB   1 
ATOM   3939 H  HG11 . VAL A 1 253 ? 2.18497   -13.81253 2.40311  1.000 25.02942 ? 276 VAL A HG11 1 
ATOM   3940 H  HG12 . VAL A 1 253 ? 1.09583   -14.47066 3.35398  1.000 25.02942 ? 276 VAL A HG12 1 
ATOM   3941 H  HG13 . VAL A 1 253 ? 1.53932   -15.21285 2.02132  1.000 25.02942 ? 276 VAL A HG13 1 
ATOM   3942 H  HG21 . VAL A 1 253 ? 1.48935   -12.42905 0.51307  1.000 27.22938 ? 276 VAL A HG21 1 
ATOM   3943 H  HG22 . VAL A 1 253 ? 1.16796   -13.82060 -0.18249 1.000 27.22938 ? 276 VAL A HG22 1 
ATOM   3944 H  HG23 . VAL A 1 253 ? 0.06709   -12.67581 -0.15010 1.000 27.22938 ? 276 VAL A HG23 1 
ATOM   3945 N  N    . LEU A 1 254 ? -2.12633  -14.77555 3.50997  1.000 17.99053 ? 277 LEU A N    1 
ATOM   3946 C  CA   . LEU A 1 254 ? -2.59087  -15.52168 4.67384  1.000 16.59118 ? 277 LEU A CA   1 
ATOM   3947 C  C    . LEU A 1 254 ? -3.55917  -16.63217 4.28096  1.000 16.96765 ? 277 LEU A C    1 
ATOM   3948 O  O    . LEU A 1 254 ? -3.52402  -17.71998 4.86413  1.000 16.90152 ? 277 LEU A O    1 
ATOM   3949 C  CB   . LEU A 1 254 ? -3.26389  -14.58314 5.66793  1.000 19.76392 ? 277 LEU A CB   1 
ATOM   3950 C  CG   . LEU A 1 254 ? -2.52056  -13.29522 6.00357  1.000 16.17810 ? 277 LEU A CG   1 
ATOM   3951 C  CD1  . LEU A 1 254 ? -3.32659  -12.53569 7.07591  1.000 17.84015 ? 277 LEU A CD1  1 
ATOM   3952 C  CD2  . LEU A 1 254 ? -1.07848  -13.57836 6.41009  1.000 14.54451 ? 277 LEU A CD2  1 
ATOM   3953 H  H    . LEU A 1 254 ? -2.41510  -13.96774 3.44940  1.000 21.56855 ? 277 LEU A H    1 
ATOM   3954 H  HA   . LEU A 1 254 ? -1.81835  -15.92442 5.10036  1.000 19.88934 ? 277 LEU A HA   1 
ATOM   3955 H  HB2  . LEU A 1 254 ? -4.12536  -14.32736 5.30278  1.000 23.69662 ? 277 LEU A HB2  1 
ATOM   3956 H  HB3  . LEU A 1 254 ? -3.38647  -15.06589 6.50029  1.000 23.69662 ? 277 LEU A HB3  1 
ATOM   3957 H  HG   . LEU A 1 254 ? -2.44728  -12.72055 5.22556  1.000 19.39364 ? 277 LEU A HG   1 
ATOM   3958 H  HD11 . LEU A 1 254 ? -2.82733  -11.75007 7.34873  1.000 21.38810 ? 277 LEU A HD11 1 
ATOM   3959 H  HD12 . LEU A 1 254 ? -4.18077  -12.27081 6.70025  1.000 21.38810 ? 277 LEU A HD12 1 
ATOM   3960 H  HD13 . LEU A 1 254 ? -3.46704  -13.11942 7.83778  1.000 21.38810 ? 277 LEU A HD13 1 
ATOM   3961 H  HD21 . LEU A 1 254 ? -0.66138  -12.74937 6.69239  1.000 17.43333 ? 277 LEU A HD21 1 
ATOM   3962 H  HD22 . LEU A 1 254 ? -1.07583  -14.21574 7.14128  1.000 17.43333 ? 277 LEU A HD22 1 
ATOM   3963 H  HD23 . LEU A 1 254 ? -0.60222  -13.94590 5.64917  1.000 17.43333 ? 277 LEU A HD23 1 
ATOM   3964 N  N    . ALA A 1 255 ? -4.44795  -16.38067 3.31664  1.000 17.95912 ? 278 ALA A N    1 
ATOM   3965 C  CA   . ALA A 1 255 ? -5.33791  -17.44125 2.85548  1.000 17.48627 ? 278 ALA A CA   1 
ATOM   3966 C  C    . ALA A 1 255 ? -4.53104  -18.59704 2.28062  1.000 19.83921 ? 278 ALA A C    1 
ATOM   3967 O  O    . ALA A 1 255 ? -4.84094  -19.77145 2.53888  1.000 17.44931 ? 278 ALA A O    1 
ATOM   3968 C  CB   . ALA A 1 255 ? -6.33203  -16.89471 1.82507  1.000 17.71694 ? 278 ALA A CB   1 
ATOM   3969 H  H    . ALA A 1 255 ? -4.55192  -15.62273 2.92380  1.000 21.53087 ? 278 ALA A H    1 
ATOM   3970 H  HA   . ALA A 1 255 ? -5.85730  -17.77350 3.60431  1.000 20.96344 ? 278 ALA A HA   1 
ATOM   3971 H  HB1  . ALA A 1 255 ? -6.94623  -17.60185 1.57287  1.000 21.24025 ? 278 ALA A HB1  1 
ATOM   3972 H  HB2  . ALA A 1 255 ? -6.82184  -16.15625 2.21961  1.000 21.24025 ? 278 ALA A HB2  1 
ATOM   3973 H  HB3  . ALA A 1 255 ? -5.84256  -16.58816 1.04574  1.000 21.24025 ? 278 ALA A HB3  1 
ATOM   3974 N  N    . SER A 1 256 ? -3.47307  -18.28015 1.53291  1.000 18.57180 ? 279 SER A N    1 
ATOM   3975 C  CA   . SER A 1 256 ? -2.61406  -19.30727 0.94393  1.000 18.17994 ? 279 SER A CA   1 
ATOM   3976 C  C    . SER A 1 256 ? -1.87311  -20.10213 2.01451  1.000 16.48280 ? 279 SER A C    1 
ATOM   3977 O  O    . SER A 1 256 ? -1.75106  -21.32729 1.91431  1.000 18.08111 ? 279 SER A O    1 
ATOM   3978 C  CB   . SER A 1 256 ? -1.61547  -18.66025 -0.01604 1.000 19.69213 ? 279 SER A CB   1 
ATOM   3979 O  OG   . SER A 1 256 ? -2.27408  -18.18198 -1.17608 1.000 23.52622 ? 279 SER A OG   1 
ATOM   3980 H  H    . SER A 1 256 ? -3.22940  -17.47584 1.35038  1.000 22.26608 ? 279 SER A H    1 
ATOM   3981 H  HA   . SER A 1 256 ? -3.17042  -19.92436 0.44335  1.000 21.79585 ? 279 SER A HA   1 
ATOM   3982 H  HB2  . SER A 1 256 ? -1.18284  -17.91633 0.43153  1.000 23.61048 ? 279 SER A HB2  1 
ATOM   3983 H  HB3  . SER A 1 256 ? -0.95433  -19.32030 -0.27704 1.000 23.61048 ? 279 SER A HB3  1 
ATOM   3984 H  HG   . SER A 1 256 ? -2.87318  -17.63391 -0.96094 1.000 28.21138 ? 279 SER A HG   1 
ATOM   3985 N  N    . ALA A 1 257 ? -1.35435  -19.43057 3.03343  1.000 17.43819 ? 280 ALA A N    1 
ATOM   3986 C  CA   . ALA A 1 257 ? -0.69178  -20.16423 4.10308  1.000 16.08887 ? 280 ALA A CA   1 
ATOM   3987 C  C    . ALA A 1 257 ? -1.67369  -21.07458 4.82301  1.000 19.04148 ? 280 ALA A C    1 
ATOM   3988 O  O    . ALA A 1 257 ? -1.35706  -22.23273 5.12205  1.000 17.89909 ? 280 ALA A O    1 
ATOM   3989 C  CB   . ALA A 1 257 ? -0.05396  -19.20606 5.10723  1.000 17.34607 ? 280 ALA A CB   1 
ATOM   3990 H  H    . ALA A 1 257 ? -1.37119  -18.57595 3.12797  1.000 20.90575 ? 280 ALA A H    1 
ATOM   3991 H  HA   . ALA A 1 257 ? 0.01389   -20.70065 3.70914  1.000 19.28657 ? 280 ALA A HA   1 
ATOM   3992 H  HB1  . ALA A 1 257 ? 0.40402   -19.72205 5.78908  1.000 20.79520 ? 280 ALA A HB1  1 
ATOM   3993 H  HB2  . ALA A 1 257 ? 0.57903   -18.63677 4.64233  1.000 20.79520 ? 280 ALA A HB2  1 
ATOM   3994 H  HB3  . ALA A 1 257 ? -0.74931  -18.66508 5.51309  1.000 20.79520 ? 280 ALA A HB3  1 
ATOM   3995 N  N    . ALA A 1 258 ? -2.87727  -20.57028 5.09453  1.000 15.88561 ? 281 ALA A N    1 
ATOM   3996 C  CA   . ALA A 1 258 ? -3.89591  -21.40020 5.72099  1.000 16.84676 ? 281 ALA A CA   1 
ATOM   3997 C  C    . ALA A 1 258 ? -4.18625  -22.63745 4.87612  1.000 21.19511 ? 281 ALA A C    1 
ATOM   3998 O  O    . ALA A 1 258 ? -4.26466  -23.75786 5.39754  1.000 17.86670 ? 281 ALA A O    1 
ATOM   3999 C  CB   . ALA A 1 258 ? -5.18360  -20.60208 5.95031  1.000 17.88444 ? 281 ALA A CB   1 
ATOM   4000 H  H    . ALA A 1 258 ? -3.12306  -19.76321 4.92775  1.000 19.04265 ? 281 ALA A H    1 
ATOM   4001 H  HA   . ALA A 1 258 ? -3.56459  -21.68388 6.58739  1.000 20.19603 ? 281 ALA A HA   1 
ATOM   4002 H  HB1  . ALA A 1 258 ? -5.83477  -21.17225 6.38824  1.000 21.44124 ? 281 ALA A HB1  1 
ATOM   4003 H  HB2  . ALA A 1 258 ? -4.98466  -19.83593 6.51097  1.000 21.44124 ? 281 ALA A HB2  1 
ATOM   4004 H  HB3  . ALA A 1 258 ? -5.52756  -20.30458 5.09353  1.000 21.44124 ? 281 ALA A HB3  1 
ATOM   4005 N  N    A LYS A 1 259 ? -4.37091  -22.45015 3.56444  0.511 16.44192 ? 282 LYS A N    1 
ATOM   4006 N  N    B LYS A 1 259 ? -4.37450  -22.45207 3.56495  0.489 16.44899 ? 282 LYS A N    1 
ATOM   4007 C  CA   A LYS A 1 259 ? -4.62069  -23.57835 2.68234  0.511 20.53059 ? 282 LYS A CA   1 
ATOM   4008 C  CA   B LYS A 1 259 ? -4.62343  -23.59030 2.69627  0.489 20.51939 ? 282 LYS A CA   1 
ATOM   4009 C  C    A LYS A 1 259 ? -3.47120  -24.57807 2.72039  0.511 20.42215 ? 282 LYS A C    1 
ATOM   4010 C  C    B LYS A 1 259 ? -3.46952  -24.58361 2.74305  0.489 20.42340 ? 282 LYS A C    1 
ATOM   4011 O  O    A LYS A 1 259 ? -3.69547  -25.79111 2.75387  0.511 21.87253 ? 282 LYS A O    1 
ATOM   4012 O  O    B LYS A 1 259 ? -3.68818  -25.79650 2.81037  0.489 21.81413 ? 282 LYS A O    1 
ATOM   4013 C  CB   A LYS A 1 259 ? -4.83837  -23.06787 1.25525  0.511 23.12441 ? 282 LYS A CB   1 
ATOM   4014 C  CB   B LYS A 1 259 ? -4.85216  -23.10971 1.26214  0.489 23.14675 ? 282 LYS A CB   1 
ATOM   4015 C  CG   A LYS A 1 259 ? -5.05620  -24.16044 0.22501  0.511 29.63606 ? 282 LYS A CG   1 
ATOM   4016 C  CG   B LYS A 1 259 ? -5.07720  -24.24032 0.27522  0.489 29.62561 ? 282 LYS A CG   1 
ATOM   4017 C  CD   A LYS A 1 259 ? -6.46306  -24.73386 0.30670  0.511 25.47884 ? 282 LYS A CD   1 
ATOM   4018 C  CD   B LYS A 1 259 ? -5.08310  -23.74772 -1.17179 0.489 26.72328 ? 282 LYS A CD   1 
ATOM   4019 C  CE   A LYS A 1 259 ? -6.73097  -25.71894 -0.83522 0.511 34.80224 ? 282 LYS A CE   1 
ATOM   4020 C  CE   B LYS A 1 259 ? -5.34589  -24.90004 -2.11285 0.489 38.29426 ? 282 LYS A CE   1 
ATOM   4021 N  NZ   A LYS A 1 259 ? -6.55880  -25.08345 -2.17424 0.511 54.68637 ? 282 LYS A NZ   1 
ATOM   4022 N  NZ   B LYS A 1 259 ? -6.74820  -25.36941 -1.94622 0.489 53.80645 ? 282 LYS A NZ   1 
ATOM   4023 H  H    A LYS A 1 259 ? -4.35555  -21.68606 3.17008  0.511 19.71022 ? 282 LYS A H    1 
ATOM   4024 H  HA   A LYS A 1 259 ? -5.42333  -24.03849 2.97379  0.511 24.61663 ? 282 LYS A HA   1 
ATOM   4025 H  HA   B LYS A 1 259 ? -5.42545  -24.04471 2.99821  0.489 24.60318 ? 282 LYS A HA   1 
ATOM   4026 H  HB2  A LYS A 1 259 ? -5.62228  -22.49662 1.24731  0.511 27.72921 ? 282 LYS A HB2  1 
ATOM   4027 H  HB2  B LYS A 1 259 ? -5.63631  -22.53901 1.24458  0.489 27.75602 ? 282 LYS A HB2  1 
ATOM   4028 H  HB3  A LYS A 1 259 ? -4.05625  -22.56166 0.98517  0.511 27.72921 ? 282 LYS A HB3  1 
ATOM   4029 H  HB3  B LYS A 1 259 ? -4.07257  -22.61138 0.97092  0.489 27.75602 ? 282 LYS A HB3  1 
ATOM   4030 H  HG2  A LYS A 1 259 ? -4.92792  -23.79377 -0.66381 0.511 35.54319 ? 282 LYS A HG2  1 
ATOM   4031 H  HG2  B LYS A 1 259 ? -4.36551  -24.89261 0.36965  0.489 35.53065 ? 282 LYS A HG2  1 
ATOM   4032 H  HG3  A LYS A 1 259 ? -4.42457  -24.87978 0.38148  0.511 35.54319 ? 282 LYS A HG3  1 
ATOM   4033 H  HG3  B LYS A 1 259 ? -5.93457  -24.65616 0.45654  0.489 35.53065 ? 282 LYS A HG3  1 
ATOM   4034 H  HD2  A LYS A 1 259 ? -6.57034  -25.20482 1.14789  0.511 30.55453 ? 282 LYS A HD2  1 
ATOM   4035 H  HD2  B LYS A 1 259 ? -5.78254  -23.08585 -1.28844 0.489 32.04786 ? 282 LYS A HD2  1 
ATOM   4036 H  HD3  A LYS A 1 259 ? -7.10870  -24.01252 0.24566  0.511 30.55453 ? 282 LYS A HD3  1 
ATOM   4037 H  HD3  B LYS A 1 259 ? -4.22049  -23.36052 -1.38831 0.489 32.04786 ? 282 LYS A HD3  1 
ATOM   4038 H  HE2  A LYS A 1 259 ? -6.10894  -26.46035 -0.76964 0.511 41.74261 ? 282 LYS A HE2  1 
ATOM   4039 H  HE2  B LYS A 1 259 ? -5.21942  -24.61059 -3.02998 0.489 45.93303 ? 282 LYS A HE2  1 
ATOM   4040 H  HE3  A LYS A 1 259 ? -7.64254  -26.04383 -0.76915 0.511 41.74261 ? 282 LYS A HE3  1 
ATOM   4041 H  HE3  B LYS A 1 259 ? -4.74406  -25.63333 -1.91040 0.489 45.93303 ? 282 LYS A HE3  1 
ATOM   4042 H  HZ1  A LYS A 1 259 ? -6.85212  -25.63145 -2.81123 0.511 65.60356 ? 282 LYS A HZ1  1 
ATOM   4043 H  HZ1  B LYS A 1 259 ? -6.93271  -25.99735 -2.54934 0.489 64.54766 ? 282 LYS A HZ1  1 
ATOM   4044 H  HZ2  A LYS A 1 259 ? -7.02028  -24.32338 -2.21206 0.511 65.60356 ? 282 LYS A HZ2  1 
ATOM   4045 H  HZ2  B LYS A 1 259 ? -6.86057  -25.70953 -1.13149 0.489 64.54766 ? 282 LYS A HZ2  1 
ATOM   4046 H  HZ3  A LYS A 1 259 ? -5.69863  -24.90660 -2.31891 0.511 65.60356 ? 282 LYS A HZ3  1 
ATOM   4047 H  HZ3  B LYS A 1 259 ? -7.31184  -24.68937 -2.05559 0.489 64.54766 ? 282 LYS A HZ3  1 
ATOM   4048 N  N    . ILE A 1 260 ? -2.23161  -24.08959 2.70833  1.000 21.29369 ? 283 ILE A N    1 
ATOM   4049 C  CA   . ILE A 1 260 ? -1.08609  -24.98688 2.67515  1.000 19.68996 ? 283 ILE A CA   1 
ATOM   4050 C  C    . ILE A 1 260 ? -1.01464  -25.83467 3.94249  1.000 20.47216 ? 283 ILE A C    1 
ATOM   4051 O  O    . ILE A 1 260 ? -0.71506  -27.03263 3.88554  1.000 23.04901 ? 283 ILE A O    1 
ATOM   4052 C  CB   . ILE A 1 260 ? 0.20061   -24.16982 2.48275  1.000 23.95385 ? 283 ILE A CB   1 
ATOM   4053 C  CG1  . ILE A 1 260 ? 0.29306   -23.63839 1.04102  1.000 22.11058 ? 283 ILE A CG1  1 
ATOM   4054 C  CG2  . ILE A 1 260 ? 1.41629   -25.02917 2.81080  1.000 26.01888 ? 283 ILE A CG2  1 
ATOM   4055 C  CD1  . ILE A 1 260 ? 1.32930   -22.51389 0.91532  1.000 22.24883 ? 283 ILE A CD1  1 
ATOM   4056 H  H    . ILE A 1 260 ? -2.03447  -23.25256 2.71883  1.000 25.53235 ? 283 ILE A H    1 
ATOM   4057 H  HA   . ILE A 1 260 ? -1.19290  -25.59210 1.92468  1.000 23.60788 ? 283 ILE A HA   1 
ATOM   4058 H  HB   . ILE A 1 260 ? 0.17736   -23.41085 3.08633  1.000 28.72454 ? 283 ILE A HB   1 
ATOM   4059 H  HG12 . ILE A 1 260 ? 0.55506   -24.36152 0.44996  1.000 26.51261 ? 283 ILE A HG12 1 
ATOM   4060 H  HG13 . ILE A 1 260 ? -0.57089  -23.28777 0.77355  1.000 26.51261 ? 283 ILE A HG13 1 
ATOM   4061 H  HG21 . ILE A 1 260 ? 2.20114   -24.63702 2.39712  1.000 31.20257 ? 283 ILE A HG21 1 
ATOM   4062 H  HG22 . ILE A 1 260 ? 1.53049   -25.06032 3.77355  1.000 31.20257 ? 283 ILE A HG22 1 
ATOM   4063 H  HG23 . ILE A 1 260 ? 1.27275   -25.92423 2.46560  1.000 31.20257 ? 283 ILE A HG23 1 
ATOM   4064 H  HD11 . ILE A 1 260 ? 1.26756   -22.12521 0.02875  1.000 26.67851 ? 283 ILE A HD11 1 
ATOM   4065 H  HD12 . ILE A 1 260 ? 1.14495   -21.83811 1.58633  1.000 26.67851 ? 283 ILE A HD12 1 
ATOM   4066 H  HD13 . ILE A 1 260 ? 2.21525   -22.88398 1.05328  1.000 26.67851 ? 283 ILE A HD13 1 
ATOM   4067 N  N    . VAL A 1 261 ? -1.26990  -25.23786 5.10685  1.000 21.61032 ? 284 VAL A N    1 
ATOM   4068 C  CA   . VAL A 1 261 ? -1.00281  -25.98612 6.33651  1.000 21.34121 ? 284 VAL A CA   1 
ATOM   4069 C  C    . VAL A 1 261 ? -2.17355  -26.85756 6.74423  1.000 23.43982 ? 284 VAL A C    1 
ATOM   4070 O  O    . VAL A 1 261 ? -2.01286  -27.71121 7.63038  1.000 23.17818 ? 284 VAL A O    1 
ATOM   4071 C  CB   . VAL A 1 261 ? -0.60387  -25.06118 7.50806  1.000 21.50959 ? 284 VAL A CB   1 
ATOM   4072 C  CG1  . VAL A 1 261 ? 0.65517   -24.30935 7.13900  1.000 23.54616 ? 284 VAL A CG1  1 
ATOM   4073 C  CG2  . VAL A 1 261 ? -1.71309  -24.08293 7.87055  1.000 19.99065 ? 284 VAL A CG2  1 
ATOM   4074 H  H    . VAL A 1 261 ? -1.58148  -24.44256 5.20694  1.000 25.91231 ? 284 VAL A H    1 
ATOM   4075 H  HA   . VAL A 1 261 ? -0.24326  -26.56419 6.16378  1.000 25.58937 ? 284 VAL A HA   1 
ATOM   4076 H  HB   . VAL A 1 261 ? -0.44498  -25.60874 8.29280  1.000 25.79142 ? 284 VAL A HB   1 
ATOM   4077 H  HG11 . VAL A 1 261 ? 0.94147   -23.78014 7.89984  1.000 28.23531 ? 284 VAL A HG11 1 
ATOM   4078 H  HG12 . VAL A 1 261 ? 1.34589   -24.94755 6.90129  1.000 28.23531 ? 284 VAL A HG12 1 
ATOM   4079 H  HG13 . VAL A 1 261 ? 0.46698   -23.72931 6.38466  1.000 28.23531 ? 284 VAL A HG13 1 
ATOM   4080 H  HG21 . VAL A 1 261 ? -1.39884  -23.49663 8.57653  1.000 23.96870 ? 284 VAL A HG21 1 
ATOM   4081 H  HG22 . VAL A 1 261 ? -1.94338  -23.56161 7.08563  1.000 23.96870 ? 284 VAL A HG22 1 
ATOM   4082 H  HG23 . VAL A 1 261 ? -2.48719  -24.58190 8.17503  1.000 23.96870 ? 284 VAL A HG23 1 
ATOM   4083 N  N    . THR A 1 262 ? -3.34231  -26.69421 6.12590  1.000 20.74520 ? 285 THR A N    1 
ATOM   4084 C  CA   . THR A 1 262 ? -4.48733  -27.52677 6.44569  1.000 23.46249 ? 285 THR A CA   1 
ATOM   4085 C  C    . THR A 1 262 ? -4.77045  -28.57295 5.38368  1.000 27.55405 ? 285 THR A C    1 
ATOM   4086 O  O    . THR A 1 262 ? -5.63391  -29.43162 5.59262  1.000 34.18692 ? 285 THR A O    1 
ATOM   4087 C  CB   . THR A 1 262 ? -5.73213  -26.66874 6.68879  1.000 23.95393 ? 285 THR A CB   1 
ATOM   4088 O  OG1  . THR A 1 262 ? -6.02331  -25.86444 5.53881  1.000 21.48691 ? 285 THR A OG1  1 
ATOM   4089 C  CG2  . THR A 1 262 ? -5.52675  -25.79244 7.91695  1.000 19.16231 ? 285 THR A CG2  1 
ATOM   4090 H  H    . THR A 1 262 ? -3.49152  -26.10526 5.51724  1.000 24.87416 ? 285 THR A H    1 
ATOM   4091 H  HA   . THR A 1 262 ? -4.30170  -27.99468 7.27485  1.000 28.13491 ? 285 THR A HA   1 
ATOM   4092 H  HB   . THR A 1 262 ? -6.49751  -27.24281 6.84861  1.000 28.72464 ? 285 THR A HB   1 
ATOM   4093 H  HG1  . THR A 1 262 ? -5.40038  -25.31677 5.40606  1.000 25.76421 ? 285 THR A HG1  1 
ATOM   4094 H  HG21 . THR A 1 262 ? -6.31428  -25.24754 8.07117  1.000 22.97469 ? 285 THR A HG21 1 
ATOM   4095 H  HG22 . THR A 1 262 ? -5.36963  -26.34662 8.69740  1.000 22.97469 ? 285 THR A HG22 1 
ATOM   4096 H  HG23 . THR A 1 262 ? -4.76210  -25.21036 7.78508  1.000 22.97469 ? 285 THR A HG23 1 
ATOM   4097 N  N    . ASP A 1 263 ? -4.03696  -28.54424 4.27254  1.000 29.08824 ? 286 ASP A N    1 
ATOM   4098 C  CA   . ASP A 1 263 ? -4.18522  -29.53318 3.21239  1.000 38.12052 ? 286 ASP A CA   1 
ATOM   4099 C  C    . ASP A 1 263 ? -3.94446  -30.93845 3.74603  1.000 39.86871 ? 286 ASP A C    1 
ATOM   4100 O  O    . ASP A 1 263 ? -2.89242  -31.22338 4.32158  1.000 56.98259 ? 286 ASP A O    1 
ATOM   4101 C  CB   . ASP A 1 263 ? -3.20033  -29.19803 2.09306  1.000 38.05487 ? 286 ASP A CB   1 
ATOM   4102 C  CG   . ASP A 1 263 ? -3.31003  -30.13865 0.91516  1.000 53.20151 ? 286 ASP A CG   1 
ATOM   4103 O  OD1  . ASP A 1 263 ? -4.36763  -30.12610 0.25240  1.000 57.40639 ? 286 ASP A OD1  1 
ATOM   4104 O  OD2  . ASP A 1 263 ? -2.33879  -30.87722 0.64653  1.000 70.24150 ? 286 ASP A OD2  1 
ATOM   4105 H  H    . ASP A 1 263 ? -3.43639  -27.95145 4.10667  1.000 34.88581 ? 286 ASP A H    1 
ATOM   4106 H  HA   . ASP A 1 263 ? -5.08834  -29.50940 2.85923  1.000 45.72454 ? 286 ASP A HA   1 
ATOM   4107 H  HB2  . ASP A 1 263 ? -3.37682  -28.29854 1.77579  1.000 45.64576 ? 286 ASP A HB2  1 
ATOM   4108 H  HB3  . ASP A 1 263 ? -2.29629  -29.25610 2.43982  1.000 45.64576 ? 286 ASP A HB3  1 
ATOM   4109 N  N    . GLY A 1 264 ? -4.91798  -31.82591 3.54796  1.000 51.57463 ? 287 GLY A N    1 
ATOM   4110 C  CA   . GLY A 1 264 ? -4.86098  -33.18015 4.05628  1.000 55.97917 ? 287 GLY A CA   1 
ATOM   4111 C  C    . GLY A 1 264 ? -5.76932  -33.42417 5.24854  1.000 64.95648 ? 287 GLY A C    1 
ATOM   4112 O  O    . GLY A 1 264 ? -6.19330  -34.56292 5.46853  1.000 58.02396 ? 287 GLY A O    1 
ATOM   4113 H  H    . GLY A 1 264 ? -5.63750  -31.65435 3.10927  1.000 61.86947 ? 287 GLY A H    1 
ATOM   4114 H  HA2  . GLY A 1 264 ? -5.12045  -33.79309 3.35067  1.000 67.15493 ? 287 GLY A HA2  1 
ATOM   4115 H  HA3  . GLY A 1 264 ? -3.95064  -33.37739 4.32699  1.000 67.15493 ? 287 GLY A HA3  1 
ATOM   4116 N  N    . LEU A 1 265 ? -6.07241  -32.38558 6.01892  1.000 61.71659 ? 288 LEU A N    1 
ATOM   4117 C  CA   . LEU A 1 265 ? -7.06044  -32.51137 7.08884  1.000 68.64817 ? 288 LEU A CA   1 
ATOM   4118 C  C    . LEU A 1 265 ? -8.47733  -32.48726 6.49648  1.000 66.71281 ? 288 LEU A C    1 
ATOM   4119 O  O    . LEU A 1 265 ? -8.83572  -31.58477 5.72501  1.000 78.46070 ? 288 LEU A O    1 
ATOM   4120 C  CB   . LEU A 1 265 ? -6.88777  -31.39068 8.10974  1.000 51.96515 ? 288 LEU A CB   1 
ATOM   4121 C  CG   . LEU A 1 265 ? -5.44903  -31.03982 8.49188  1.000 44.93778 ? 288 LEU A CG   1 
ATOM   4122 C  CD1  . LEU A 1 265 ? -5.45553  -29.72759 9.26203  1.000 42.52685 ? 288 LEU A CD1  1 
ATOM   4123 C  CD2  . LEU A 1 265 ? -4.78766  -32.13626 9.30346  1.000 57.85323 ? 288 LEU A CD2  1 
ATOM   4124 H  H    . LEU A 1 265 ? -5.72377  -31.60296 5.94442  1.000 74.03982 ? 288 LEU A H    1 
ATOM   4125 H  HA   . LEU A 1 265 ? -6.93589  -33.35171 7.55706  1.000 82.35772 ? 288 LEU A HA   1 
ATOM   4126 H  HB2  . LEU A 1 265 ? -7.29142  -30.58701 7.74631  1.000 62.33810 ? 288 LEU A HB2  1 
ATOM   4127 H  HB3  . LEU A 1 265 ? -7.34461  -31.65210 8.92451  1.000 62.33810 ? 288 LEU A HB3  1 
ATOM   4128 H  HG   . LEU A 1 265 ? -4.91905  -30.94517 7.68499  1.000 53.90525 ? 288 LEU A HG   1 
ATOM   4129 H  HD11 . LEU A 1 265 ? -4.54532  -29.50307 9.51106  1.000 51.01214 ? 288 LEU A HD11 1 
ATOM   4130 H  HD12 . LEU A 1 265 ? -5.82508  -29.03141 8.69664  1.000 51.01214 ? 288 LEU A HD12 1 
ATOM   4131 H  HD13 . LEU A 1 265 ? -6.00023  -29.83123 10.05794 1.000 51.01214 ? 288 LEU A HD13 1 
ATOM   4132 H  HD21 . LEU A 1 265 ? -3.88334  -31.86379 9.52451  1.000 69.40380 ? 288 LEU A HD21 1 
ATOM   4133 H  HD22 . LEU A 1 265 ? -5.29794  -32.27935 10.11588 1.000 69.40380 ? 288 LEU A HD22 1 
ATOM   4134 H  HD23 . LEU A 1 265 ? -4.76838  -32.95084 8.77716  1.000 69.40380 ? 288 LEU A HD23 1 
HETATM 4135 C  C11  . XQN B 2 .   ? -11.92336 -5.21200  7.36812  1.000 24.20353 ? 301 XQN A C11  1 
HETATM 4136 C  C14  . XQN B 2 .   ? -10.99763 -3.13100  8.08291  1.000 25.65988 ? 301 XQN A C14  1 
HETATM 4137 O  O15  . XQN B 2 .   ? -8.72534  -1.29273  8.05234  1.000 25.75288 ? 301 XQN A O15  1 
HETATM 4138 C  C17  . XQN B 2 .   ? -7.03988  -1.11541  12.15022 1.000 17.71702 ? 301 XQN A C17  1 
HETATM 4139 B  B2   . XQN B 2 .   ? -6.13134  -3.06656  13.11601 1.000 19.83369 ? 301 XQN A B2   1 
HETATM 4140 C  C10  . XQN B 2 .   ? -10.66383 -5.76031  7.24492  1.000 20.45988 ? 301 XQN A C10  1 
HETATM 4141 C  C13  . XQN B 2 .   ? -12.10098 -3.90958  7.78391  1.000 28.38826 ? 301 XQN A C13  1 
HETATM 4142 C  C18  . XQN B 2 .   ? -7.10722  0.16820   11.61232 1.000 18.21387 ? 301 XQN A C18  1 
HETATM 4143 C  C19  . XQN B 2 .   ? -5.99074  0.97974   11.65500 1.000 27.11694 ? 301 XQN A C19  1 
HETATM 4144 C  C20  . XQN B 2 .   ? -4.81989  0.52204   12.22617 1.000 22.87106 ? 301 XQN A C20  1 
HETATM 4145 C  C21  . XQN B 2 .   ? -4.75940  -0.75590  12.75786 1.000 27.80865 ? 301 XQN A C21  1 
HETATM 4146 C  C22  . XQN B 2 .   ? -5.87491  -1.60259  12.72610 1.000 15.96968 ? 301 XQN A C22  1 
HETATM 4147 C  C4   . XQN B 2 .   ? -8.14577  -2.13597  12.12698 1.000 21.15522 ? 301 XQN A C4   1 
HETATM 4148 C  C5   . XQN B 2 .   ? -8.81183  -2.38953  10.78096 1.000 24.19714 ? 301 XQN A C5   1 
HETATM 4149 C  C8   . XQN B 2 .   ? -9.72532  -3.67538  7.95680  1.000 29.72023 ? 301 XQN A C8   1 
HETATM 4150 C  C9   . XQN B 2 .   ? -9.55760  -4.98669  7.54177  1.000 26.15541 ? 301 XQN A C9   1 
HETATM 4151 N  N6   . XQN B 2 .   ? -7.86101  -2.81444  9.75311  1.000 28.20680 ? 301 XQN A N6   1 
HETATM 4152 O  O1   . XQN B 2 .   ? -5.17675  -3.93929  12.45860 1.000 22.61264 ? 301 XQN A O1   1 
HETATM 4153 O  O16  . XQN B 2 .   ? -7.23526  -3.17226  7.42899  1.000 30.72991 ? 301 XQN A O16  1 
HETATM 4154 O  O3   . XQN B 2 .   ? -7.55181  -3.30102  12.68587 1.000 20.87532 ? 301 XQN A O3   1 
HETATM 4155 S  S7   . XQN B 2 .   ? -8.31421  -2.65751  8.21690  1.000 28.82855 ? 301 XQN A S7   1 
HETATM 4156 CL CL12 . XQN B 2 .   ? -13.31189 -6.15956  6.89348  1.000 31.60432 ? 301 XQN A CL12 1 
HETATM 4157 H  H14  . XQN B 2 .   ? -11.12054 -2.20626  8.37986  1.000 30.77178 ? 301 XQN A H14  1 
HETATM 4158 H  H10  . XQN B 2 .   ? -10.55019 -6.68711  6.95070  1.000 24.53177 ? 301 XQN A H10  1 
HETATM 4159 H  H13  . XQN B 2 .   ? -13.00118 -3.53416  7.86837  1.000 34.04583 ? 301 XQN A H13  1 
HETATM 4160 H  H18  . XQN B 2 .   ? -7.93704  0.49372   11.20750 1.000 21.83657 ? 301 XQN A H18  1 
HETATM 4161 H  H19  . XQN B 2 .   ? -6.03031  1.88268   11.27874 1.000 32.52025 ? 301 XQN A H19  1 
HETATM 4162 H  H20  . XQN B 2 .   ? -4.03129  1.10143   12.25547 1.000 27.42520 ? 301 XQN A H20  1 
HETATM 4163 H  H21  . XQN B 2 .   ? -3.91186  -1.06210  13.13597 1.000 33.35030 ? 301 XQN A H21  1 
HETATM 4164 H  H4   . XQN B 2 .   ? -8.82210  -1.81926  12.76000 1.000 25.36618 ? 301 XQN A H4   1 
HETATM 4165 H  H5B  . XQN B 2 .   ? -9.26860  -1.58164  10.46931 1.000 29.01649 ? 301 XQN A H5B  1 
HETATM 4166 H  H5A  . XQN B 2 .   ? -9.50528  -3.07511  10.86776 1.000 29.01649 ? 301 XQN A H5A  1 
HETATM 4167 H  H9   . XQN B 2 .   ? -8.66228  -5.37331  7.45589  1.000 31.36641 ? 301 XQN A H9   1 
HETATM 4168 H  H6   . XQN B 2 .   ? -7.57404  -3.63648  9.90000  1.000 33.82808 ? 301 XQN A H6   1 
HETATM 4169 H  H1   . XQN B 2 .   ? -4.41845  -3.57202  12.57081 1.000 27.11508 ? 301 XQN A H1   1 
HETATM 4170 S  S    . SO4 C 3 .   ? 9.46520   -8.18758  30.27400 1.000 58.77557 ? 302 SO4 A S    1 
HETATM 4171 O  O1   . SO4 C 3 .   ? 10.89573  -7.88790  30.21280 1.000 59.21972 ? 302 SO4 A O1   1 
HETATM 4172 O  O2   . SO4 C 3 .   ? 8.88373   -7.92388  28.95793 1.000 41.80979 ? 302 SO4 A O2   1 
HETATM 4173 O  O3   . SO4 C 3 .   ? 9.27753   -9.58985  30.67392 1.000 39.92408 ? 302 SO4 A O3   1 
HETATM 4174 O  O4   . SO4 C 3 .   ? 8.82106   -7.32873  31.25637 1.000 49.05824 ? 302 SO4 A O4   1 
HETATM 4175 S  S    . SO4 D 3 .   ? 15.61269  -20.02910 -2.24281 1.000 62.95524 ? 303 SO4 A S    1 
HETATM 4176 O  O1   . SO4 D 3 .   ? 16.52172  -21.17817 -2.18142 1.000 71.31376 ? 303 SO4 A O1   1 
HETATM 4177 O  O2   . SO4 D 3 .   ? 15.53887  -19.59071 -3.63743 1.000 54.80429 ? 303 SO4 A O2   1 
HETATM 4178 O  O3   . SO4 D 3 .   ? 14.27107  -20.40629 -1.77851 1.000 75.44524 ? 303 SO4 A O3   1 
HETATM 4179 O  O4   . SO4 D 3 .   ? 16.11735  -18.95247 -1.38601 1.000 55.20014 ? 303 SO4 A O4   1 
HETATM 4180 S  S    . SO4 E 3 .   ? 12.71827  -12.93181 4.42267  1.000 58.51457 ? 304 SO4 A S    1 
HETATM 4181 O  O1   . SO4 E 3 .   ? 13.89409  -13.50374 3.76430  1.000 72.25438 ? 304 SO4 A O1   1 
HETATM 4182 O  O2   . SO4 E 3 .   ? 11.71703  -12.64621 3.40595  1.000 48.75278 ? 304 SO4 A O2   1 
HETATM 4183 O  O3   . SO4 E 3 .   ? 12.16667  -13.90436 5.36436  1.000 59.68803 ? 304 SO4 A O3   1 
HETATM 4184 O  O4   . SO4 E 3 .   ? 13.08448  -11.70899 5.15066  1.000 48.68789 ? 304 SO4 A O4   1 
HETATM 4185 CL CL   . CL  F 4 .   ? -15.46672 -25.37523 0.23943  1.000 24.15034 ? 305 CL  A CL   1 
HETATM 4186 NA NA   . NA  G 5 .   ? 1.92246   -13.83445 21.97934 1.000 22.69857 ? 306 NA  A NA   1 
HETATM 4187 NA NA   . NA  H 5 .   ? -10.10221 -15.45615 8.88870  1.000 22.12293 ? 307 NA  A NA   1 
HETATM 4188 NA NA   . NA  I 5 .   ? -7.23053  -5.96587  10.18401 1.000 22.01146 ? 308 NA  A NA   1 
HETATM 4189 O  O    . HOH J 6 .   ? -14.53684 7.81163   12.95842 1.000 36.15036 ? 401 HOH A O    1 
HETATM 4190 O  O    . HOH J 6 .   ? -1.14108  -29.91785 4.89493  1.000 39.33081 ? 402 HOH A O    1 
HETATM 4191 O  O    . HOH J 6 .   ? -8.73804  -30.18644 3.92097  1.000 45.99345 ? 403 HOH A O    1 
HETATM 4192 O  O    . HOH J 6 .   ? -8.65482  -16.75752 34.78064 1.000 36.66468 ? 404 HOH A O    1 
HETATM 4193 O  O    . HOH J 6 .   ? -15.241   16.112    15.125   1.000 39.66624 ? 405 HOH A O    1 
HETATM 4194 O  O    . HOH J 6 .   ? -17.88200 13.26025  15.95890 1.000 46.06245 ? 406 HOH A O    1 
HETATM 4195 O  O    . HOH J 6 .   ? 10.65163  -17.37138 28.93389 1.000 28.58481 ? 407 HOH A O    1 
HETATM 4196 O  O    . HOH J 6 .   ? -25.484   -1.490    26.559   1.000 36.45514 ? 408 HOH A O    1 
HETATM 4197 O  O    . HOH J 6 .   ? -9.49767  10.94967  14.35134 1.000 24.13926 ? 409 HOH A O    1 
HETATM 4198 O  O    . HOH J 6 .   ? -23.05974 -4.79332  36.60975 1.000 45.59804 ? 410 HOH A O    1 
HETATM 4199 O  O    . HOH J 6 .   ? -22.127   10.805    28.494   1.000 38.09970 ? 411 HOH A O    1 
HETATM 4200 O  O    . HOH J 6 .   ? -0.69665  5.91306   19.87388 1.000 18.73928 ? 412 HOH A O    1 
HETATM 4201 O  O    . HOH J 6 .   ? 13.56161  -18.01772 11.79575 1.000 31.36431 ? 413 HOH A O    1 
HETATM 4202 O  O    . HOH J 6 .   ? -19.81243 4.03359   11.71918 1.000 37.82866 ? 414 HOH A O    1 
HETATM 4203 O  O    . HOH J 6 .   ? 5.77575   -24.80904 20.59399 1.000 28.76921 ? 415 HOH A O    1 
HETATM 4204 O  O    . HOH J 6 .   ? -0.10702  -19.45853 27.91478 1.000 26.61521 ? 416 HOH A O    1 
HETATM 4205 O  O    . HOH J 6 .   ? -4.12618  -2.36747  15.99674 1.000 15.00738 ? 417 HOH A O    1 
HETATM 4206 O  O    . HOH J 6 .   ? -18.85213 -8.40742  34.42892 1.000 36.44766 ? 418 HOH A O    1 
HETATM 4207 O  O    . HOH J 6 .   ? 10.294    -13.146   -5.121   1.000 21.85843 ? 419 HOH A O    1 
HETATM 4208 O  O    . HOH J 6 .   ? -20.63692 -15.23757 17.69258 1.000 35.08388 ? 420 HOH A O    1 
HETATM 4209 O  O    . HOH J 6 .   ? 2.98597   -7.33040  -2.14217 1.000 34.42911 ? 421 HOH A O    1 
HETATM 4210 O  O    . HOH J 6 .   ? -4.71477  -22.37888 31.41234 1.000 23.51914 ? 422 HOH A O    1 
HETATM 4211 O  O    . HOH J 6 .   ? -20.170   -16.117   28.651   1.000 21.61569 ? 423 HOH A O    1 
HETATM 4212 O  O    . HOH J 6 .   ? 9.51945   -16.03514 34.39861 1.000 24.16254 ? 424 HOH A O    1 
HETATM 4213 O  O    . HOH J 6 .   ? -23.51139 -3.86941  27.78046 1.000 38.12229 ? 425 HOH A O    1 
HETATM 4214 O  O    . HOH J 6 .   ? 7.49145   -5.17458  9.69811  1.000 21.57118 ? 426 HOH A O    1 
HETATM 4215 O  O    . HOH J 6 .   ? -9.55412  -4.08971  40.57949 1.000 33.44353 ? 427 HOH A O    1 
HETATM 4216 O  O    . HOH J 6 .   ? 7.33890   -0.14818  14.73366 1.000 17.12798 ? 428 HOH A O    1 
HETATM 4217 O  O    . HOH J 6 .   ? -18.41192 -13.79311 31.14220 1.000 27.47227 ? 429 HOH A O    1 
HETATM 4218 O  O    . HOH J 6 .   ? -12.07541 15.79300  25.82137 1.000 38.54920 ? 430 HOH A O    1 
HETATM 4219 O  O    . HOH J 6 .   ? -11.54629 -7.95765  13.99588 1.000 25.34930 ? 431 HOH A O    1 
HETATM 4220 O  O    . HOH J 6 .   ? -4.97739  3.24052   33.13490 1.000 31.79950 ? 432 HOH A O    1 
HETATM 4221 O  O    . HOH J 6 .   ? -8.90519  -21.91209 34.99038 1.000 30.26716 ? 433 HOH A O    1 
HETATM 4222 O  O    . HOH J 6 .   ? -17.93347 -30.74989 13.10583 1.000 44.88638 ? 434 HOH A O    1 
HETATM 4223 O  O    . HOH J 6 .   ? 6.79482   -2.69818  15.70659 1.000 18.35486 ? 435 HOH A O    1 
HETATM 4224 O  O    . HOH J 6 .   ? -18.51670 -27.42695 10.35925 1.000 42.72773 ? 436 HOH A O    1 
HETATM 4225 O  O    . HOH J 6 .   ? -12.65418 2.10652   32.18135 1.000 27.74057 ? 437 HOH A O    1 
HETATM 4226 O  O    . HOH J 6 .   ? -14.21659 -16.11041 2.86689  1.000 30.57308 ? 438 HOH A O    1 
HETATM 4227 O  O    . HOH J 6 .   ? -0.99831  -23.34343 25.04952 1.000 26.48861 ? 439 HOH A O    1 
HETATM 4228 O  O    . HOH J 6 .   ? 10.17979  -12.94401 0.26978  1.000 18.79595 ? 440 HOH A O    1 
HETATM 4229 O  O    . HOH J 6 .   ? -8.71474  6.60647   21.92360 1.000 18.50749 ? 441 HOH A O    1 
HETATM 4230 O  O    . HOH J 6 .   ? -9.51348  -11.46298 38.16154 1.000 36.39190 ? 442 HOH A O    1 
HETATM 4231 O  O    . HOH J 6 .   ? 2.00928   -4.11556  16.30759 1.000 15.26787 ? 443 HOH A O    1 
HETATM 4232 O  O    . HOH J 6 .   ? -7.79547  -31.45199 13.74102 1.000 22.77959 ? 444 HOH A O    1 
HETATM 4233 O  O    . HOH J 6 .   ? -0.540    -36.981   20.304   1.000 32.82601 ? 445 HOH A O    1 
HETATM 4234 O  O    . HOH J 6 .   ? -24.09672 -1.32927  30.96849 1.000 28.04146 ? 446 HOH A O    1 
HETATM 4235 O  O    . HOH J 6 .   ? 3.05336   6.18401   20.97055 1.000 26.59845 ? 447 HOH A O    1 
HETATM 4236 O  O    . HOH J 6 .   ? -23.67498 5.57069   23.37735 1.000 37.50239 ? 448 HOH A O    1 
HETATM 4237 O  O    . HOH J 6 .   ? -7.45039  10.66630  20.33131 1.000 26.19926 ? 449 HOH A O    1 
HETATM 4238 O  O    . HOH J 6 .   ? 7.845     -12.882   -6.534   1.000 21.84375 ? 450 HOH A O    1 
HETATM 4239 O  O    . HOH J 6 .   ? -9.53247  -10.14858 6.29399  1.000 21.55955 ? 451 HOH A O    1 
HETATM 4240 O  O    . HOH J 6 .   ? 8.73493   -17.81131 20.13128 1.000 23.26715 ? 452 HOH A O    1 
HETATM 4241 O  O    . HOH J 6 .   ? 1.60903   -0.23315  4.33075  1.000 19.06146 ? 453 HOH A O    1 
HETATM 4242 O  O    . HOH J 6 .   ? 0.14401   -28.45592 1.71646  1.000 36.16759 ? 454 HOH A O    1 
HETATM 4243 O  O    . HOH J 6 .   ? 11.79280  -17.72127 1.48618  1.000 31.32428 ? 455 HOH A O    1 
HETATM 4244 O  O    . HOH J 6 .   ? -13.95801 -30.76816 5.27164  1.000 38.21618 ? 456 HOH A O    1 
HETATM 4245 O  O    . HOH J 6 .   ? 3.89404   -31.40173 12.13269 1.000 38.14719 ? 457 HOH A O    1 
HETATM 4246 O  O    . HOH J 6 .   ? 4.42142   -1.56907  15.31304 1.000 17.76887 ? 458 HOH A O    1 
HETATM 4247 O  O    . HOH J 6 .   ? 14.14730  -13.13924 9.32203  1.000 36.79946 ? 459 HOH A O    1 
HETATM 4248 O  O    . HOH J 6 .   ? -15.24258 -20.28046 7.48743  1.000 36.16536 ? 460 HOH A O    1 
HETATM 4249 O  O    . HOH J 6 .   ? -14.73961 -2.81555  10.90499 1.000 27.22348 ? 461 HOH A O    1 
HETATM 4250 O  O    . HOH J 6 .   ? 8.27581   -4.34227  13.80970 1.000 20.62509 ? 462 HOH A O    1 
HETATM 4251 O  O    . HOH J 6 .   ? -9.63694  -19.85130 28.60269 1.000 19.35599 ? 463 HOH A O    1 
HETATM 4252 O  O    . HOH J 6 .   ? 4.73926   -2.68860  27.97728 1.000 29.20424 ? 464 HOH A O    1 
HETATM 4253 O  O    . HOH J 6 .   ? -12.59566 -1.17304  37.82148 1.000 41.02699 ? 465 HOH A O    1 
HETATM 4254 O  O    . HOH J 6 .   ? 6.16215   -8.02982  -0.80982 1.000 29.62035 ? 466 HOH A O    1 
HETATM 4255 O  O    . HOH J 6 .   ? -5.43667  -27.71863 1.07221  1.000 43.04666 ? 467 HOH A O    1 
HETATM 4256 O  O    . HOH J 6 .   ? -7.93647  -25.83330 3.54333  1.000 31.37450 ? 468 HOH A O    1 
HETATM 4257 O  O    . HOH J 6 .   ? -14.09382 -0.55027  6.97927  1.000 35.23825 ? 469 HOH A O    1 
HETATM 4258 O  O    . HOH J 6 .   ? -18.31317 -34.77354 15.29300 1.000 42.94163 ? 470 HOH A O    1 
HETATM 4259 O  O    . HOH J 6 .   ? -11.03669 -27.17956 24.72479 1.000 36.17649 ? 471 HOH A O    1 
HETATM 4260 O  O    . HOH J 6 .   ? -8.030    -13.246   0.081    1.000 25.05555 ? 472 HOH A O    1 
HETATM 4261 O  O    . HOH J 6 .   ? -5.380    -16.371   38.226   1.000 35.29629 ? 473 HOH A O    1 
HETATM 4262 O  O    . HOH J 6 .   ? 8.49502   -19.45177 -4.87982 0.924 24.59168 ? 474 HOH A O    1 
HETATM 4263 O  O    . HOH J 6 .   ? -10.18998 -26.63852 28.44682 1.000 42.32719 ? 475 HOH A O    1 
HETATM 4264 O  O    . HOH J 6 .   ? 1.55349   -18.92401 26.22746 1.000 31.56630 ? 476 HOH A O    1 
HETATM 4265 O  O    . HOH J 6 .   ? -5.66174  -9.83069  7.64637  1.000 17.37434 ? 477 HOH A O    1 
HETATM 4266 O  O    . HOH J 6 .   ? -16.36534 15.22837  22.96682 1.000 33.37936 ? 478 HOH A O    1 
HETATM 4267 O  O    . HOH J 6 .   ? -20.37613 -13.32732 29.14339 1.000 27.13563 ? 479 HOH A O    1 
HETATM 4268 O  O    . HOH J 6 .   ? 4.04371   -11.26743 -4.77011 1.000 37.95115 ? 480 HOH A O    1 
HETATM 4269 O  O    . HOH J 6 .   ? -14.96982 -12.57314 9.61103  1.000 28.66758 ? 481 HOH A O    1 
HETATM 4270 O  O    . HOH J 6 .   ? -13.89437 -20.84745 5.35289  1.000 24.45536 ? 482 HOH A O    1 
HETATM 4271 O  O    . HOH J 6 .   ? -17.12117 -27.41848 12.40496 1.000 44.68513 ? 483 HOH A O    1 
HETATM 4272 O  O    . HOH J 6 .   ? -5.05693  -8.00138  0.60319  1.000 26.43549 ? 484 HOH A O    1 
HETATM 4273 O  O    . HOH J 6 .   ? -6.181    -20.078   34.776   1.000 31.07415 ? 485 HOH A O    1 
HETATM 4274 O  O    . HOH J 6 .   ? 10.97535  -14.40212 19.68315 1.000 38.29022 ? 486 HOH A O    1 
HETATM 4275 O  O    . HOH J 6 .   ? -16.85152 -14.13998 7.88689  1.000 37.32697 ? 487 HOH A O    1 
HETATM 4276 O  O    . HOH J 6 .   ? 4.83693   -5.23695  31.78961 1.000 30.05954 ? 488 HOH A O    1 
HETATM 4277 O  O    . HOH J 6 .   ? -20.90020 -7.01870  34.09568 1.000 41.97459 ? 489 HOH A O    1 
HETATM 4278 O  O    . HOH J 6 .   ? 4.09717   2.57865   6.89687  1.000 37.27270 ? 490 HOH A O    1 
HETATM 4279 O  O    . HOH J 6 .   ? 9.73976   -5.91826  6.64456  1.000 37.45867 ? 491 HOH A O    1 
HETATM 4280 O  O    . HOH J 6 .   ? 7.32850   3.82549   22.19785 1.000 25.17913 ? 492 HOH A O    1 
HETATM 4281 O  O    . HOH J 6 .   ? -1.13255  -3.42539  5.44752  1.000 31.92225 ? 493 HOH A O    1 
HETATM 4282 O  O    . HOH J 6 .   ? 5.09634   2.69279   9.24573  1.000 27.83812 ? 494 HOH A O    1 
HETATM 4283 O  O    . HOH J 6 .   ? -1.80556  -17.91089 35.54486 1.000 26.77539 ? 495 HOH A O    1 
HETATM 4284 O  O    . HOH J 6 .   ? -11.84142 -11.33152 17.10682 1.000 14.75377 ? 496 HOH A O    1 
HETATM 4285 O  O    . HOH J 6 .   ? 0.900     0.706     31.253   1.000 30.54763 ? 497 HOH A O    1 
HETATM 4286 O  O    . HOH J 6 .   ? 12.56305  -2.44207  4.78828  1.000 36.98392 ? 498 HOH A O    1 
HETATM 4287 O  O    . HOH J 6 .   ? -4.082    7.418     21.724   1.000 39.10414 ? 499 HOH A O    1 
HETATM 4288 O  O    . HOH J 6 .   ? 4.10476   -16.70950 34.62494 1.000 39.81951 ? 500 HOH A O    1 
HETATM 4289 O  O    . HOH J 6 .   ? -16.90567 -19.29913 10.80025 1.000 28.98212 ? 501 HOH A O    1 
HETATM 4290 O  O    . HOH J 6 .   ? 10.82689  -8.07534  7.62878  1.000 34.07872 ? 502 HOH A O    1 
HETATM 4291 O  O    . HOH J 6 .   ? -16.08646 -4.61722  9.48505  1.000 30.23459 ? 503 HOH A O    1 
HETATM 4292 O  O    . HOH J 6 .   ? 9.86275   -10.31338 25.38712 1.000 43.20265 ? 504 HOH A O    1 
HETATM 4293 O  O    . HOH J 6 .   ? 12.01594  -9.20029  1.22401  1.000 37.40483 ? 505 HOH A O    1 
HETATM 4294 O  O    . HOH J 6 .   ? -19.57938 7.37891   9.20449  1.000 53.05343 ? 506 HOH A O    1 
HETATM 4295 O  O    . HOH J 6 .   ? 7.004     -17.133   25.727   1.000 25.85904 ? 507 HOH A O    1 
HETATM 4296 O  O    . HOH J 6 .   ? -11.64200 2.47256   29.92391 1.000 33.66652 ? 508 HOH A O    1 
HETATM 4297 O  O    . HOH J 6 .   ? -2.22929  -7.11767  34.26208 1.000 28.94821 ? 509 HOH A O    1 
HETATM 4298 O  O    . HOH J 6 .   ? -7.63651  -33.89805 12.32241 1.000 36.69011 ? 510 HOH A O    1 
HETATM 4299 O  O    . HOH J 6 .   ? -6.13729  -26.83739 29.22439 1.000 29.30607 ? 511 HOH A O    1 
HETATM 4300 O  O    . HOH J 6 .   ? 9.014     -10.464   33.425   1.000 41.43916 ? 512 HOH A O    1 
HETATM 4301 O  O    . HOH J 6 .   ? -6.235    -27.587   24.616   1.000 42.80931 ? 513 HOH A O    1 
HETATM 4302 O  O    . HOH J 6 .   ? -4.51403  -5.05509  -1.15242 1.000 40.94120 ? 514 HOH A O    1 
HETATM 4303 O  O    . HOH J 6 .   ? -6.50948  -7.24445  7.52783  1.000 32.72228 ? 515 HOH A O    1 
HETATM 4304 O  O    . HOH J 6 .   ? -13.45167 5.54229   11.33468 1.000 30.63117 ? 516 HOH A O    1 
HETATM 4305 O  O    . HOH J 6 .   ? -19.63693 -5.65282  17.93434 1.000 34.29277 ? 517 HOH A O    1 
HETATM 4306 O  O    . HOH J 6 .   ? 7.33479   -6.42258  12.33675 1.000 26.26181 ? 518 HOH A O    1 
HETATM 4307 O  O    . HOH J 6 .   ? -16.27498 -22.20952 28.17634 1.000 34.31108 ? 519 HOH A O    1 
HETATM 4308 O  O    . HOH J 6 .   ? 5.815     -18.160   32.861   1.000 29.78092 ? 520 HOH A O    1 
HETATM 4309 O  O    . HOH J 6 .   ? -17.47943 -12.05995 32.83949 1.000 34.01256 ? 521 HOH A O    1 
HETATM 4310 O  O    A HOH J 6 .   ? 0.21692   -37.85532 14.03427 0.474 29.77187 ? 522 HOH A O    1 
HETATM 4311 O  O    B HOH J 6 .   ? 0.64148   -39.43498 13.42371 0.526 29.57108 ? 522 HOH A O    1 
HETATM 4312 O  O    . HOH J 6 .   ? 2.73396   3.15891   26.69405 1.000 28.15359 ? 523 HOH A O    1 
HETATM 4313 O  O    . HOH J 6 .   ? 11.76575  -7.87728  23.24174 1.000 36.11461 ? 524 HOH A O    1 
HETATM 4314 O  O    . HOH J 6 .   ? -17.06979 -26.70003 2.61212  1.000 23.54610 ? 525 HOH A O    1 
HETATM 4315 O  O    . HOH J 6 .   ? -20.68383 -24.37413 8.97275  1.000 46.44953 ? 526 HOH A O    1 
HETATM 4316 O  O    . HOH J 6 .   ? -15.76218 -16.71324 5.01124  1.000 38.96680 ? 527 HOH A O    1 
HETATM 4317 O  O    . HOH J 6 .   ? 12.26455  0.51679   19.32263 1.000 32.92197 ? 528 HOH A O    1 
HETATM 4318 O  O    . HOH J 6 .   ? 9.81781   -6.69515  9.74055  1.000 25.49483 ? 529 HOH A O    1 
HETATM 4319 O  O    . HOH J 6 .   ? 2.87589   -10.86769 35.46249 1.000 32.36873 ? 530 HOH A O    1 
HETATM 4320 O  O    . HOH J 6 .   ? -21.19243 -11.51065 19.55636 1.000 39.13860 ? 531 HOH A O    1 
HETATM 4321 O  O    . HOH J 6 .   ? -17.83654 -19.22685 34.76272 1.000 40.33908 ? 532 HOH A O    1 
HETATM 4322 O  O    . HOH J 6 .   ? -20.79663 2.39381   35.12610 1.000 33.89744 ? 533 HOH A O    1 
HETATM 4323 O  O    . HOH J 6 .   ? -21.89376 -12.09442 23.03389 1.000 35.69439 ? 534 HOH A O    1 
HETATM 4324 O  O    . HOH J 6 .   ? -1.48376  -31.04700 11.47615 1.000 38.54496 ? 535 HOH A O    1 
HETATM 4325 O  O    . HOH J 6 .   ? 12.89600  -11.61598 15.14075 1.000 30.06582 ? 536 HOH A O    1 
HETATM 4326 O  O    . HOH J 6 .   ? 11.49128  -21.60410 9.96999  1.000 28.81876 ? 537 HOH A O    1 
HETATM 4327 O  O    . HOH J 6 .   ? 5.29475   5.70578   17.83687 1.000 25.98787 ? 538 HOH A O    1 
HETATM 4328 O  O    . HOH J 6 .   ? 3.432     4.123     24.912   1.000 33.73217 ? 539 HOH A O    1 
HETATM 4329 O  O    . HOH J 6 .   ? 9.91531   -21.92512 12.94052 1.000 22.81313 ? 540 HOH A O    1 
HETATM 4330 O  O    . HOH J 6 .   ? -0.61501  1.66928   1.16020  1.000 45.13872 ? 541 HOH A O    1 
HETATM 4331 O  O    . HOH J 6 .   ? 7.07462   -27.57857 11.92565 1.000 34.56165 ? 542 HOH A O    1 
HETATM 4332 O  O    . HOH J 6 .   ? 11.83514  -19.13695 13.91872 1.000 23.02765 ? 543 HOH A O    1 
HETATM 4333 O  O    . HOH J 6 .   ? 3.56216   -29.65830 20.47597 1.000 45.58998 ? 544 HOH A O    1 
HETATM 4334 O  O    . HOH J 6 .   ? -15.52345 7.15421   31.30460 1.000 32.78247 ? 545 HOH A O    1 
HETATM 4335 O  O    . HOH J 6 .   ? -21.51932 -8.71275  23.80099 1.000 43.68216 ? 546 HOH A O    1 
HETATM 4336 O  O    . HOH J 6 .   ? 14.05400  -0.45327  13.64631 1.000 38.37173 ? 547 HOH A O    1 
HETATM 4337 O  O    . HOH J 6 .   ? 13.45694  -3.35220  23.44476 1.000 36.38859 ? 548 HOH A O    1 
HETATM 4338 O  O    . HOH J 6 .   ? -13.62498 7.25010   29.21685 1.000 37.44374 ? 549 HOH A O    1 
HETATM 4339 O  O    . HOH J 6 .   ? -0.67169  -15.66844 -2.58428 1.000 42.36103 ? 550 HOH A O    1 
HETATM 4340 O  O    . HOH J 6 .   ? -9.75169  1.35407   35.54211 1.000 40.12382 ? 551 HOH A O    1 
HETATM 4341 O  O    . HOH J 6 .   ? -18.69289 -20.00101 22.98378 1.000 40.14718 ? 552 HOH A O    1 
HETATM 4342 O  O    . HOH J 6 .   ? 2.52570   -3.18299  -2.58051 1.000 29.27878 ? 553 HOH A O    1 
HETATM 4343 O  O    . HOH J 6 .   ? -13.86355 -23.68065 23.42429 1.000 45.13834 ? 554 HOH A O    1 
HETATM 4344 O  O    . HOH J 6 .   ? -5.04703  -17.00385 -1.77612 1.000 38.92774 ? 555 HOH A O    1 
HETATM 4345 O  O    . HOH J 6 .   ? -22.72525 -0.52574  20.00560 1.000 46.83178 ? 556 HOH A O    1 
HETATM 4346 O  O    . HOH J 6 .   ? -14.53810 -21.49166 35.53105 1.000 40.02378 ? 557 HOH A O    1 
HETATM 4347 O  O    . HOH J 6 .   ? 7.96801   5.71189   16.11211 1.000 40.27627 ? 558 HOH A O    1 
HETATM 4348 O  O    . HOH J 6 .   ? 4.92918   -4.22675  -2.43624 1.000 43.49842 ? 559 HOH A O    1 
HETATM 4349 O  O    . HOH J 6 .   ? -9.97363  -21.96849 -0.50753 1.000 41.40741 ? 560 HOH A O    1 
HETATM 4350 O  O    . HOH J 6 .   ? 4.95355   -31.34510 16.14604 1.000 37.42405 ? 561 HOH A O    1 
HETATM 4351 O  O    . HOH J 6 .   ? 6.89073   6.43726   18.84907 1.000 37.29806 ? 562 HOH A O    1 
HETATM 4352 O  O    . HOH J 6 .   ? -21.59348 8.43546   32.89127 1.000 45.67402 ? 563 HOH A O    1 
HETATM 4353 O  O    . HOH J 6 .   ? -14.84208 -15.09585 12.50142 1.000 37.71441 ? 564 HOH A O    1 
HETATM 4354 O  O    . HOH J 6 .   ? -20.81720 -19.11572 20.03984 1.000 46.31241 ? 565 HOH A O    1 
HETATM 4355 O  O    . HOH J 6 .   ? -20.36981 -3.29183  20.12964 1.000 39.95869 ? 566 HOH A O    1 
HETATM 4356 O  O    . HOH J 6 .   ? -13.11792 -17.52303 37.26362 1.000 40.13402 ? 567 HOH A O    1 
HETATM 4357 O  O    . HOH J 6 .   ? -5.36663  -34.56533 12.09429 1.000 33.78634 ? 568 HOH A O    1 
HETATM 4358 O  O    . HOH J 6 .   ? -13.99404 15.90553  23.41570 1.000 31.69435 ? 569 HOH A O    1 
HETATM 4359 O  O    . HOH J 6 .   ? 14.76153  -12.17806 0.91962  1.000 34.71211 ? 570 HOH A O    1 
HETATM 4360 O  O    . HOH J 6 .   ? 2.71235   -35.30603 17.57973 1.000 46.32586 ? 571 HOH A O    1 
HETATM 4361 O  O    . HOH J 6 .   ? -13.837   -27.247   21.377   1.000 36.23875 ? 572 HOH A O    1 
HETATM 4362 O  O    . HOH J 6 .   ? -10.92259 -0.01456  37.28053 1.000 42.49110 ? 573 HOH A O    1 
HETATM 4363 O  O    . HOH J 6 .   ? -21.38863 -9.61381  14.59373 1.000 50.45315 ? 574 HOH A O    1 
HETATM 4364 O  O    . HOH J 6 .   ? -16.55733 -29.71137 3.31383  1.000 42.04982 ? 575 HOH A O    1 
HETATM 4365 O  O    . HOH J 6 .   ? -5.969    0.115     36.047   1.000 34.77290 ? 576 HOH A O    1 
HETATM 4366 O  O    . HOH J 6 .   ? 2.48310   -28.02305 22.01777 1.000 38.07250 ? 577 HOH A O    1 
HETATM 4367 O  O    . HOH J 6 .   ? -4.80709  -0.68348  9.05320  1.000 36.48426 ? 578 HOH A O    1 
HETATM 4368 O  O    . HOH J 6 .   ? 1.51708   -1.38427  -4.44452 1.000 42.57823 ? 579 HOH A O    1 
HETATM 4369 O  O    . HOH J 6 .   ? -5.861    -8.392    34.172   1.000 41.81025 ? 580 HOH A O    1 
HETATM 4370 O  O    . HOH J 6 .   ? -2.06692  2.68878   11.29100 1.000 36.53734 ? 581 HOH A O    1 
HETATM 4371 O  O    . HOH J 6 .   ? 5.088     -10.797   -7.660   1.000 30.80936 ? 582 HOH A O    1 
HETATM 4372 O  O    . HOH J 6 .   ? 5.938     -3.366    -4.786   1.000 35.33950 ? 583 HOH A O    1 
HETATM 4373 O  O    . HOH J 6 .   ? -10.71804 -23.83665 0.27288  1.000 39.03570 ? 584 HOH A O    1 
HETATM 4374 O  O    . HOH J 6 .   ? 5.88902   -35.48105 9.85331  1.000 52.88743 ? 585 HOH A O    1 
HETATM 4375 O  O    . HOH J 6 .   ? 4.28929   -8.26524  -4.95518 1.000 45.59739 ? 586 HOH A O    1 
HETATM 4376 O  O    . HOH J 6 .   ? -18.913   -15.730   36.018   1.000 45.77531 ? 587 HOH A O    1 
HETATM 4377 O  O    . HOH J 6 .   ? -6.27661  -31.99804 23.90674 1.000 45.20646 ? 588 HOH A O    1 
HETATM 4378 O  O    . HOH J 6 .   ? 12.85051  -13.78817 0.08186  1.000 40.15322 ? 589 HOH A O    1 
HETATM 4379 O  O    . HOH J 6 .   ? 1.79182   3.32385   6.12663  1.000 47.65081 ? 590 HOH A O    1 
HETATM 4380 O  O    . HOH J 6 .   ? 16.55468  -17.09078 6.20631  1.000 42.09247 ? 591 HOH A O    1 
HETATM 4381 O  O    . HOH J 6 .   ? 13.51545  -8.17157  21.73742 1.000 47.91250 ? 592 HOH A O    1 
HETATM 4382 O  O    . HOH J 6 .   ? 7.82272   -19.05969 22.64145 1.000 38.63889 ? 593 HOH A O    1 
HETATM 4383 O  O    . HOH J 6 .   ? 10.56679  -16.18338 20.84725 1.000 43.10273 ? 594 HOH A O    1 
HETATM 4384 O  O    . HOH J 6 .   ? 3.51439   -20.07178 -4.02996 1.000 55.51745 ? 595 HOH A O    1 
HETATM 4385 O  O    . HOH J 6 .   ? -2.266    -36.146   21.738   1.000 28.73590 ? 596 HOH A O    1 
HETATM 4386 O  O    . HOH J 6 .   ? -3.21310  -0.58763  7.13116  1.000 44.59090 ? 597 HOH A O    1 
HETATM 4387 O  O    . HOH J 6 .   ? -21.139   -16.403   26.074   1.000 30.28482 ? 598 HOH A O    1 
HETATM 4388 O  O    . HOH J 6 .   ? 5.50919   -20.36551 23.10104 1.000 32.32753 ? 599 HOH A O    1 
HETATM 4389 O  O    . HOH J 6 .   ? -2.06167  -22.23691 -1.89089 1.000 49.24680 ? 600 HOH A O    1 
HETATM 4390 O  O    . HOH J 6 .   ? -6.50908  -20.00860 -1.03237 1.000 39.79185 ? 601 HOH A O    1 
HETATM 4391 O  O    . HOH J 6 .   ? -6.53804  8.81731   22.23383 1.000 33.82079 ? 602 HOH A O    1 
HETATM 4392 O  O    . HOH J 6 .   ? -22.35662 -18.35753 18.71018 1.000 52.30614 ? 603 HOH A O    1 
HETATM 4393 O  O    . HOH J 6 .   ? -16.37989 -21.89148 24.60541 1.000 45.45807 ? 604 HOH A O    1 
HETATM 4394 O  O    . HOH J 6 .   ? -17.72149 -23.50662 26.60110 1.000 48.18524 ? 605 HOH A O    1 
HETATM 4395 O  O    . HOH J 6 .   ? -9.59103  4.74886   32.29816 1.000 35.52879 ? 606 HOH A O    1 
HETATM 4396 O  O    . HOH J 6 .   ? -11.68251 17.59076  22.38770 1.000 39.58642 ? 607 HOH A O    1 
HETATM 4397 O  O    . HOH J 6 .   ? -19.75603 -27.00712 2.50641  1.000 34.17767 ? 608 HOH A O    1 
HETATM 4398 O  O    . HOH J 6 .   ? -20.55809 -4.87041  9.27015  1.000 46.19100 ? 609 HOH A O    1 
HETATM 4399 O  O    . HOH J 6 .   ? -1.60185  -27.05840 -0.76762 1.000 38.65822 ? 610 HOH A O    1 
HETATM 4400 O  O    . HOH J 6 .   ? 3.44774   5.15938   5.47277  1.000 46.81858 ? 611 HOH A O    1 
HETATM 4401 O  O    . HOH J 6 .   ? -15.303   -3.563    6.967    1.000 38.67095 ? 612 HOH A O    1 
HETATM 4402 O  O    . HOH J 6 .   ? 15.02681  -17.76673 17.84729 1.000 45.65918 ? 613 HOH A O    1 
HETATM 4403 O  O    . HOH J 6 .   ? 14.28654  -17.76471 14.81032 1.000 42.50539 ? 614 HOH A O    1 
HETATM 4404 O  O    . HOH J 6 .   ? -22.609   13.720    29.276   1.000 45.54282 ? 615 HOH A O    1 
HETATM 4405 O  O    . HOH J 6 .   ? -7.25531  -15.36582 -1.50021 1.000 40.60148 ? 616 HOH A O    1 
HETATM 4406 O  O    . HOH J 6 .   ? 4.51022   6.96283   15.87071 1.000 45.03930 ? 617 HOH A O    1 
HETATM 4407 O  O    . HOH J 6 .   ? 12.58794  -5.42990  5.72569  1.000 44.65864 ? 618 HOH A O    1 
HETATM 4408 O  O    . HOH J 6 .   ? 6.88888   6.26649   14.04729 1.000 45.67780 ? 619 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . THR A 4   ? 0.96152 0.67962 1.06595 0.10509  0.20529  0.02454  27  THR A N   
2    C CA  . THR A 4   ? 0.87066 0.54947 0.94696 0.08975  0.24399  -0.00218 27  THR A CA  
3    C C   . THR A 4   ? 0.80666 0.52696 0.91291 0.10350  0.23795  0.00581  27  THR A C   
4    O O   . THR A 4   ? 0.79429 0.56072 0.90745 0.10657  0.20138  0.00882  27  THR A O   
5    C CB  . THR A 4   ? 0.91158 0.55349 0.91125 0.04613  0.24330  -0.04547 27  THR A CB  
6    O OG1 . THR A 4   ? 1.17981 0.79395 1.15280 0.03050  0.24247  -0.05125 27  THR A OG1 
7    C CG2 . THR A 4   ? 0.98372 0.58487 0.94672 0.02125  0.28552  -0.07015 27  THR A CG2 
14   N N   . ALA A 5   ? 0.89708 0.60087 1.02386 0.11185  0.27703  0.01163  28  ALA A N   
15   C CA  . ALA A 5   ? 0.85845 0.59465 1.00527 0.11889  0.27511  0.01374  28  ALA A CA  
16   C C   . ALA A 5   ? 0.81612 0.52906 0.89989 0.08628  0.27540  -0.02786 28  ALA A C   
17   O O   . ALA A 5   ? 0.82532 0.57355 0.91378 0.08782  0.25945  -0.03109 28  ALA A O   
18   C CB  . ALA A 5   ? 0.82430 0.54584 1.01142 0.13536  0.31954  0.03291  28  ALA A CB  
24   N N   . ASP A 6   ? 0.76365 0.42328 0.78512 0.05203  0.29220  -0.05808 29  ASP A N   
25   C CA  . ASP A 6   ? 0.80017 0.44984 0.75565 0.01221  0.28602  -0.09269 29  ASP A CA  
26   C C   . ASP A 6   ? 0.67951 0.37494 0.62159 0.00891  0.23678  -0.09657 29  ASP A C   
27   O O   . ASP A 6   ? 0.61395 0.33322 0.53463 -0.00332 0.22364  -0.10780 29  ASP A O   
28   C CB  . ASP A 6   ? 0.80685 0.40458 0.69821 -0.03149 0.30911  -0.11793 29  ASP A CB  
29   C CG  . ASP A 6   ? 1.00126 0.58962 0.83145 -0.07697 0.31543  -0.14471 29  ASP A CG  
30   O OD1 . ASP A 6   ? 1.15787 0.76626 0.99855 -0.07020 0.31293  -0.14462 29  ASP A OD1 
31   O OD2 . ASP A 6   ? 1.15234 0.71869 0.92442 -0.12197 0.32142  -0.16302 29  ASP A OD2 
36   N N   A VAL A 7   ? 0.59137 0.29797 0.54435 0.01819  0.21124  -0.08605 30  VAL A N   
37   N N   B VAL A 7   ? 0.58832 0.29459 0.54149 0.01829  0.21152  -0.08594 30  VAL A N   
38   C CA  A VAL A 7   ? 0.52416 0.29261 0.47181 0.01125  0.15669  -0.07777 30  VAL A CA  
39   C CA  B VAL A 7   ? 0.52307 0.29118 0.47198 0.01203  0.15684  -0.07717 30  VAL A CA  
40   C C   A VAL A 7   ? 0.48434 0.30779 0.47764 0.03665  0.13872  -0.05633 30  VAL A C   
41   C C   B VAL A 7   ? 0.48399 0.30695 0.47723 0.03664  0.13898  -0.05639 30  VAL A C   
42   O O   A VAL A 7   ? 0.41038 0.27264 0.38739 0.02488  0.11057  -0.05775 30  VAL A O   
43   O O   B VAL A 7   ? 0.40672 0.26760 0.38257 0.02430  0.11146  -0.05848 30  VAL A O   
44   C CB  A VAL A 7   ? 0.49137 0.27251 0.44988 0.01495  0.12935  -0.06276 30  VAL A CB  
45   C CB  B VAL A 7   ? 0.48785 0.26815 0.45054 0.01769  0.13061  -0.06099 30  VAL A CB  
46   C CG1 A VAL A 7   ? 0.52441 0.31224 0.54571 0.05357  0.13540  -0.03140 30  VAL A CG1 
47   C CG1 B VAL A 7   ? 0.48752 0.33090 0.45508 0.01503  0.08110  -0.04765 30  VAL A CG1 
48   C CG2 A VAL A 7   ? 0.48175 0.32187 0.43367 0.00515  0.08032  -0.05446 30  VAL A CG2 
49   C CG2 B VAL A 7   ? 0.62750 0.35933 0.53850 -0.01489 0.14474  -0.08444 30  VAL A CG2 
68   N N   . GLN A 8   ? 0.53475 0.36487 0.58755 0.07068  0.15638  -0.03299 31  GLN A N   
69   C CA  . GLN A 8   ? 0.50007 0.38610 0.59514 0.08866  0.14276  -0.01306 31  GLN A CA  
70   C C   . GLN A 8   ? 0.44356 0.32258 0.51115 0.07470  0.15856  -0.03524 31  GLN A C   
71   O O   . GLN A 8   ? 0.45897 0.37922 0.51983 0.06752  0.13283  -0.03371 31  GLN A O   
72   C CB  . GLN A 8   ? 0.59558 0.49612 0.76033 0.12271  0.16241  0.01989  31  GLN A CB  
73   C CG  . GLN A 8   ? 0.63128 0.55854 0.82325 0.13275  0.13626  0.04971  31  GLN A CG  
74   C CD  . GLN A 8   ? 0.53893 0.52627 0.73227 0.12469  0.09018  0.06100  31  GLN A CD  
75   O OE1 . GLN A 8   ? 0.44173 0.46908 0.64086 0.12029  0.07903  0.06189  31  GLN A OE1 
76   N NE2 . GLN A 8   ? 0.50482 0.49449 0.68305 0.11547  0.06473  0.06620  31  GLN A NE2 
86   N N   . GLN A 9   ? 0.52023 0.34169 0.56994 0.06942  0.20616  -0.05609 32  GLN A N   
87   C CA  . GLN A 9   ? 0.59621 0.40930 0.61387 0.05038  0.22129  -0.07655 32  GLN A CA  
88   C C   . GLN A 9   ? 0.48423 0.30813 0.43650 0.01504  0.19146  -0.09593 32  GLN A C   
89   O O   . GLN A 9   ? 0.48062 0.33139 0.42038 0.00716  0.18032  -0.09822 32  GLN A O   
90   C CB  . GLN A 9   ? 0.64942 0.40491 0.64845 0.03530  0.26349  -0.08873 32  GLN A CB  
91   C CG  . GLN A 9   ? 0.71005 0.45104 0.66545 0.00661  0.27716  -0.11099 32  GLN A CG  
92   C CD  . GLN A 9   ? 0.93347 0.61892 0.88496 -0.00403 0.32656  -0.11795 32  GLN A CD  
93   O OE1 . GLN A 9   ? 1.08614 0.74721 1.07567 0.01584  0.35371  -0.10213 32  GLN A OE1 
94   N NE2 . GLN A 9   ? 0.83393 0.49850 0.73912 -0.03711 0.34061  -0.13914 32  GLN A NE2 
103  N N   . LYS A 10  ? 0.48452 0.29480 0.39818 -0.00740 0.17511  -0.10402 33  LYS A N   
104  C CA  . LYS A 10  ? 0.47557 0.31040 0.33675 -0.04068 0.14290  -0.11127 33  LYS A CA  
105  C C   . LYS A 10  ? 0.43087 0.32662 0.32112 -0.02420 0.10112  -0.08666 33  LYS A C   
106  O O   . LYS A 10  ? 0.37023 0.29065 0.23723 -0.03745 0.08597  -0.08536 33  LYS A O   
107  C CB  . LYS A 10  ? 0.48591 0.30406 0.30825 -0.06857 0.13378  -0.12045 33  LYS A CB  
108  C CG  . LYS A 10  ? 0.58251 0.34726 0.35545 -0.10502 0.16891  -0.14528 33  LYS A CG  
109  C CD  . LYS A 10  ? 0.86055 0.62979 0.60014 -0.13712 0.15015  -0.14728 33  LYS A CD  
110  C CE  . LYS A 10  ? 0.89837 0.64676 0.58949 -0.18547 0.16934  -0.15992 33  LYS A CE  
111  N NZ  . LYS A 10  ? 1.07249 0.75324 0.76509 -0.18477 0.22294  -0.17251 33  LYS A NZ  
125  N N   . LEU A 11  ? 0.34833 0.26590 0.28606 0.00205  0.08533  -0.06616 34  LEU A N   
126  C CA  . LEU A 11  ? 0.33598 0.30027 0.29261 0.01099  0.05465  -0.04764 34  LEU A CA  
127  C C   . LEU A 11  ? 0.26846 0.25050 0.24041 0.01951  0.06360  -0.04526 34  LEU A C   
128  O O   . LEU A 11  ? 0.28388 0.29006 0.24621 0.01451  0.04794  -0.03944 34  LEU A O   
129  C CB  . LEU A 11  ? 0.28083 0.26203 0.27578 0.02846  0.03910  -0.02885 34  LEU A CB  
130  C CG  . LEU A 11  ? 0.31322 0.28413 0.29405 0.01939  0.02504  -0.02870 34  LEU A CG  
131  C CD1 . LEU A 11  ? 0.31933 0.30446 0.33793 0.03608  0.01426  -0.00938 34  LEU A CD1 
132  C CD2 . LEU A 11  ? 0.29753 0.28817 0.25112 0.00238  0.00276  -0.02736 34  LEU A CD2 
144  N N   . ALA A 12  ? 0.29764 0.26797 0.29793 0.03384  0.09206  -0.04710 35  ALA A N   
145  C CA  . ALA A 12  ? 0.32592 0.31606 0.34188 0.03935  0.10291  -0.04568 35  ALA A CA  
146  C C   . ALA A 12  ? 0.38372 0.35765 0.34729 0.01596  0.10985  -0.06467 35  ALA A C   
147  O O   . ALA A 12  ? 0.35459 0.35105 0.31343 0.01275  0.10250  -0.06121 35  ALA A O   
148  C CB  . ALA A 12  ? 0.34871 0.33176 0.41213 0.06092  0.13732  -0.04043 35  ALA A CB  
154  N N   . GLU A 13  ? 0.37109 0.30546 0.29074 -0.00483 0.12570  -0.08433 36  GLU A N   
155  C CA  . GLU A 13  ? 0.41725 0.34191 0.27961 -0.03477 0.12931  -0.09929 36  GLU A CA  
156  C C   . GLU A 13  ? 0.39944 0.36000 0.24103 -0.04518 0.09076  -0.08321 36  GLU A C   
157  O O   . GLU A 13  ? 0.38094 0.35561 0.20168 -0.05441 0.08635  -0.07951 36  GLU A O   
158  C CB  . GLU A 13  ? 0.46770 0.34391 0.27956 -0.06484 0.15495  -0.12434 36  GLU A CB  
159  C CG  . GLU A 13  ? 0.63823 0.47231 0.47718 -0.05406 0.19733  -0.13327 36  GLU A CG  
160  C CD  . GLU A 13  ? 0.69888 0.48420 0.50319 -0.08295 0.21758  -0.14812 36  GLU A CD  
161  O OE1 . GLU A 13  ? 0.76236 0.55249 0.52998 -0.10778 0.19608  -0.15077 36  GLU A OE1 
162  O OE2 . GLU A 13  ? 0.84263 0.58679 0.65856 -0.08257 0.25676  -0.15477 36  GLU A OE2 
169  N N   . LEU A 14  ? 0.35841 0.33277 0.20849 -0.04217 0.06625  -0.07088 37  LEU A N   
170  C CA  . LEU A 14  ? 0.36987 0.37869 0.21579 -0.04391 0.03639  -0.04959 37  LEU A CA  
171  C C   . LEU A 14  ? 0.30006 0.32693 0.17352 -0.02471 0.03385  -0.03664 37  LEU A C   
172  O O   . LEU A 14  ? 0.30399 0.34478 0.16187 -0.02961 0.02756  -0.02470 37  LEU A O   
173  C CB  . LEU A 14  ? 0.33275 0.35123 0.19427 -0.03923 0.01699  -0.03889 37  LEU A CB  
174  C CG  . LEU A 14  ? 0.30464 0.35565 0.17476 -0.03472 -0.00617 -0.01349 37  LEU A CG  
175  C CD1 . LEU A 14  ? 0.35065 0.42391 0.18531 -0.05768 -0.01611 -0.00207 37  LEU A CD1 
176  C CD2 . LEU A 14  ? 0.27178 0.32731 0.16136 -0.02933 -0.01919 -0.00672 37  LEU A CD2 
188  N N   . GLU A 15  ? 0.31968 0.34868 0.23303 -0.00556 0.03905  -0.03586 38  GLU A N   
189  C CA  . GLU A 15  ? 0.26946 0.31644 0.20167 0.00312  0.03782  -0.02614 38  GLU A CA  
190  C C   . GLU A 15  ? 0.32237 0.36692 0.23763 -0.00365 0.05355  -0.03322 38  GLU A C   
191  O O   . GLU A 15  ? 0.27215 0.32278 0.17570 -0.00672 0.05177  -0.02462 38  GLU A O   
192  C CB  . GLU A 15  ? 0.25308 0.31386 0.22708 0.01600  0.03900  -0.02201 38  GLU A CB  
193  C CG  . GLU A 15  ? 0.27765 0.35985 0.26353 0.01422  0.04049  -0.01562 38  GLU A CG  
194  C CD  . GLU A 15  ? 0.24741 0.35858 0.27314 0.01929  0.03729  -0.00612 38  GLU A CD  
195  O OE1 . GLU A 15  ? 0.23556 0.35913 0.29143 0.02923  0.04920  -0.00480 38  GLU A OE1 
196  O OE2 . GLU A 15  ? 0.22981 0.35320 0.25737 0.01176  0.02500  0.00256  38  GLU A OE2 
203  N N   . ARG A 16  ? 0.32851 0.35859 0.24176 -0.00613 0.07427  -0.04898 39  ARG A N   
204  C CA  . ARG A 16  ? 0.34016 0.36532 0.23667 -0.01431 0.09321  -0.05833 39  ARG A CA  
205  C C   . ARG A 16  ? 0.35283 0.37398 0.19967 -0.03328 0.08482  -0.05448 39  ARG A C   
206  O O   . ARG A 16  ? 0.34494 0.37202 0.18140 -0.03600 0.08789  -0.04865 39  ARG A O   
207  C CB  . ARG A 16  ? 0.34758 0.34813 0.24673 -0.01559 0.12389  -0.07730 39  ARG A CB  
208  C CG  . ARG A 16  ? 0.36499 0.35626 0.24757 -0.02535 0.14968  -0.09018 39  ARG A CG  
209  C CD  . ARG A 16  ? 0.41490 0.37837 0.31798 -0.02013 0.18038  -0.10222 39  ARG A CD  
210  N NE  . ARG A 16  ? 0.44596 0.37112 0.31255 -0.03815 0.18564  -0.11486 39  ARG A NE  
211  C CZ  . ARG A 16  ? 0.52651 0.41376 0.40089 -0.03940 0.21516  -0.12570 39  ARG A CZ  
212  N NH1 . ARG A 16  ? 0.63685 0.52194 0.56048 -0.01831 0.24147  -0.12161 39  ARG A NH1 
213  N NH2 . ARG A 16  ? 0.56068 0.41289 0.39331 -0.06497 0.21938  -0.13811 39  ARG A NH2 
227  N N   . GLN A 17  ? 0.33990 0.35411 0.15498 -0.04921 0.07501  -0.05514 40  GLN A N   
228  C CA  . GLN A 17  ? 0.43388 0.45821 0.20500 -0.07004 0.06327  -0.04301 40  GLN A CA  
229  C C   . GLN A 17  ? 0.34354 0.39148 0.13128 -0.05561 0.04453  -0.01262 40  GLN A C   
230  O O   . GLN A 17  ? 0.37204 0.42803 0.14153 -0.06106 0.04189  0.00440  40  GLN A O   
231  C CB  . GLN A 17  ? 0.41388 0.43671 0.15925 -0.09299 0.05159  -0.04506 40  GLN A CB  
232  C CG  . GLN A 17  ? 0.45136 0.49169 0.17017 -0.11553 0.03669  -0.02860 40  GLN A CG  
233  C CD  . GLN A 17  ? 0.73704 0.81513 0.47287 -0.10348 0.01126  0.00927  40  GLN A CD  
234  O OE1 . GLN A 17  ? 0.67719 0.76690 0.44003 -0.08506 0.00165  0.02175  40  GLN A OE1 
235  N NE2 . GLN A 17  ? 0.68033 0.77601 0.40433 -0.11293 0.00353  0.02919  40  GLN A NE2 
244  N N   . SER A 18  ? 0.31112 0.36492 0.13564 -0.03666 0.03514  -0.00434 41  SER A N   
245  C CA  . SER A 18  ? 0.31563 0.38117 0.15553 -0.02375 0.02686  0.02271  41  SER A CA  
246  C C   . SER A 18  ? 0.34580 0.40045 0.18973 -0.01661 0.04390  0.02526  41  SER A C   
247  O O   . SER A 18  ? 0.31941 0.37319 0.16458 -0.00934 0.04732  0.04899  41  SER A O   
248  C CB  . SER A 18  ? 0.27116 0.33833 0.14301 -0.01071 0.01844  0.02545  41  SER A CB  
249  O OG  . SER A 18  ? 0.26625 0.32384 0.15963 -0.00336 0.02887  0.01076  41  SER A OG  
256  N N   . GLY A 19  ? 0.30553 0.35194 0.15441 -0.01863 0.05810  0.00354  42  GLY A N   
257  C CA  . GLY A 19  ? 0.32473 0.36359 0.17442 -0.01854 0.07501  0.00259  42  GLY A CA  
258  C C   . GLY A 19  ? 0.33498 0.37311 0.20877 -0.01402 0.07857  0.00279  42  GLY A C   
259  O O   . GLY A 19  ? 0.31169 0.34420 0.18316 -0.02129 0.09437  -0.00187 42  GLY A O   
263  N N   . GLY A 20  ? 0.24078 0.28402 0.13264 -0.00758 0.06541  0.00676  43  GLY A N   
264  C CA  . GLY A 20  ? 0.29184 0.33246 0.19748 -0.01026 0.06941  0.00698  43  GLY A CA  
265  C C   . GLY A 20  ? 0.29542 0.35761 0.22661 -0.01132 0.05766  -0.00162 43  GLY A C   
266  O O   . GLY A 20  ? 0.25276 0.33060 0.19789 -0.00798 0.05519  -0.00940 43  GLY A O   
270  N N   . ARG A 21  ? 0.24192 0.30303 0.17986 -0.01623 0.05427  0.00212  44  ARG A N   
271  C CA  . ARG A 21  ? 0.18613 0.27146 0.14705 -0.01992 0.04132  0.00113  44  ARG A CA  
272  C C   . ARG A 21  ? 0.19014 0.26511 0.15482 -0.01232 0.02928  0.00720  44  ARG A C   
273  O O   . ARG A 21  ? 0.19976 0.25311 0.15178 -0.01555 0.03686  0.01192  44  ARG A O   
274  C CB  . ARG A 21  ? 0.21225 0.31078 0.16850 -0.04464 0.04842  -0.00066 44  ARG A CB  
275  C CG  . ARG A 21  ? 0.19764 0.33403 0.17821 -0.05253 0.03129  0.00613  44  ARG A CG  
276  C CD  . ARG A 21  ? 0.19495 0.36288 0.16941 -0.08574 0.03550  0.00627  44  ARG A CD  
277  N NE  . ARG A 21  ? 0.24344 0.37016 0.17922 -0.10859 0.04897  -0.00305 44  ARG A NE  
278  C CZ  . ARG A 21  ? 0.23779 0.35683 0.16297 -0.12348 0.04199  -0.00290 44  ARG A CZ  
279  N NH1 . ARG A 21  ? 0.23522 0.39913 0.18079 -0.12776 0.02157  0.01119  44  ARG A NH1 
280  N NH2 . ARG A 21  ? 0.29097 0.35698 0.18816 -0.13345 0.05694  -0.01563 44  ARG A NH2 
294  N N   . LEU A 22  ? 0.21964 0.30651 0.20318 -0.00200 0.01548  0.00754  45  LEU A N   
295  C CA  . LEU A 22  ? 0.19847 0.27567 0.18428 0.00458  0.00408  0.01148  45  LEU A CA  
296  C C   . LEU A 22  ? 0.19577 0.28785 0.20050 0.00179  -0.00649 0.01594  45  LEU A C   
297  O O   . LEU A 22  ? 0.16126 0.27603 0.18818 0.00482  -0.00853 0.01934  45  LEU A O   
298  C CB  . LEU A 22  ? 0.24533 0.31600 0.22785 0.01353  0.00075  0.00687  45  LEU A CB  
299  C CG  . LEU A 22  ? 0.20982 0.27303 0.19274 0.01596  -0.01036 0.00826  45  LEU A CG  
300  C CD1 . LEU A 22  ? 0.21651 0.27731 0.18979 0.01409  -0.01446 0.01884  45  LEU A CD1 
301  C CD2 . LEU A 22  ? 0.31380 0.36675 0.28589 0.01508  -0.00651 -0.00237 45  LEU A CD2 
313  N N   . GLY A 23  ? 0.23077 0.31249 0.22972 -0.00337 -0.01153 0.01960  46  GLY A N   
314  C CA  . GLY A 23  ? 0.19653 0.29147 0.20819 -0.00864 -0.02312 0.02614  46  GLY A CA  
315  C C   . GLY A 23  ? 0.19651 0.27425 0.20798 -0.00119 -0.03067 0.02686  46  GLY A C   
316  O O   . GLY A 23  ? 0.17626 0.23687 0.17577 -0.00208 -0.02614 0.02579  46  GLY A O   
320  N N   . VAL A 24  ? 0.17129 0.25411 0.19934 0.00695  -0.03935 0.03132  47  VAL A N   
321  C CA  . VAL A 24  ? 0.18675 0.25119 0.21192 0.01122  -0.04480 0.02976  47  VAL A CA  
322  C C   . VAL A 24  ? 0.17891 0.25045 0.21786 0.00989  -0.05365 0.04115  47  VAL A C   
323  O O   . VAL A 24  ? 0.15107 0.24266 0.21270 0.01628  -0.05488 0.05331  47  VAL A O   
324  C CB  . VAL A 24  ? 0.22999 0.27965 0.25227 0.02061  -0.03948 0.02069  47  VAL A CB  
325  C CG1 . VAL A 24  ? 0.19540 0.22744 0.21070 0.01809  -0.04401 0.01777  47  VAL A CG1 
326  C CG2 . VAL A 24  ? 0.21861 0.26779 0.22347 0.01794  -0.03425 0.01403  47  VAL A CG2 
336  N N   . ALA A 25  ? 0.17858 0.23760 0.20752 0.00212  -0.05901 0.04139  48  ALA A N   
337  C CA  . ALA A 25  ? 0.16285 0.22237 0.20085 0.00148  -0.06736 0.05283  48  ALA A CA  
338  C C   . ALA A 25  ? 0.18709 0.22013 0.21432 0.00145  -0.06741 0.04460  48  ALA A C   
339  O O   . ALA A 25  ? 0.21890 0.24594 0.23316 -0.00801 -0.06614 0.03886  48  ALA A O   
340  C CB  . ALA A 25  ? 0.19532 0.26835 0.22348 -0.01900 -0.06925 0.05932  48  ALA A CB  
346  N N   . LEU A 26  ? 0.22015 0.23599 0.25404 0.01146  -0.06426 0.04441  49  LEU A N   
347  C CA  . LEU A 26  ? 0.21517 0.20700 0.23657 0.00598  -0.06397 0.03687  49  LEU A CA  
348  C C   . LEU A 26  ? 0.24779 0.23096 0.27723 0.00722  -0.06721 0.05126  49  LEU A C   
349  O O   . LEU A 26  ? 0.26104 0.24494 0.31105 0.02130  -0.06205 0.06601  49  LEU A O   
350  C CB  . LEU A 26  ? 0.25216 0.22130 0.26318 0.00766  -0.05211 0.02218  49  LEU A CB  
351  C CG  . LEU A 26  ? 0.26538 0.21007 0.25955 -0.00464 -0.05008 0.01353  49  LEU A CG  
352  C CD1 . LEU A 26  ? 0.28964 0.25411 0.27351 -0.01931 -0.06059 0.00942  49  LEU A CD1 
353  C CD2 . LEU A 26  ? 0.39498 0.30520 0.37274 -0.00865 -0.03018 -0.00161 49  LEU A CD2 
365  N N   . ILE A 27  ? 0.24591 0.22219 0.26275 -0.00609 -0.07346 0.05054  50  ILE A N   
366  C CA  . ILE A 27  ? 0.22599 0.18858 0.24394 -0.00785 -0.07607 0.06344  50  ILE A CA  
367  C C   . ILE A 27  ? 0.20577 0.13627 0.20860 -0.01371 -0.06858 0.04828  50  ILE A C   
368  O O   . ILE A 27  ? 0.25913 0.19407 0.25020 -0.02623 -0.07085 0.03529  50  ILE A O   
369  C CB  . ILE A 27  ? 0.19361 0.17222 0.20170 -0.02615 -0.08727 0.07353  50  ILE A CB  
370  C CG1 . ILE A 27  ? 0.25008 0.26309 0.26619 -0.03032 -0.08720 0.08215  50  ILE A CG1 
371  C CG2 . ILE A 27  ? 0.30987 0.27176 0.31353 -0.03083 -0.09041 0.08641  50  ILE A CG2 
372  C CD1 . ILE A 27  ? 0.27744 0.29864 0.27199 -0.05891 -0.08795 0.08160  50  ILE A CD1 
384  N N   . ASN A 28  ? 0.26302 0.16227 0.26808 -0.00544 -0.05628 0.05154  51  ASN A N   
385  C CA  . ASN A 28  ? 0.35702 0.22109 0.34068 -0.01782 -0.04547 0.03479  51  ASN A CA  
386  C C   . ASN A 28  ? 0.29170 0.13678 0.27314 -0.02102 -0.04658 0.04856  51  ASN A C   
387  O O   . ASN A 28  ? 0.31434 0.14332 0.31127 -0.00500 -0.03810 0.06964  51  ASN A O   
388  C CB  . ASN A 28  ? 0.32351 0.15078 0.30023 -0.01278 -0.02071 0.02248  51  ASN A CB  
389  C CG  . ASN A 28  ? 0.48435 0.27660 0.42833 -0.03676 -0.00806 0.00057  51  ASN A CG  
390  O OD1 . ASN A 28  ? 0.38539 0.18161 0.31918 -0.05233 -0.01839 -0.00103 51  ASN A OD1 
391  N ND2 . ASN A 28  ? 0.46930 0.22599 0.39311 -0.04452 0.01721  -0.01788 51  ASN A ND2 
398  N N   . THR A 29  ? 0.33218 0.18159 0.31452 0.00100  0.05636  0.01855  52  THR A N   
399  C CA  . THR A 29  ? 0.36060 0.19390 0.33852 0.00403  0.06679  0.03018  52  THR A CA  
400  C C   . THR A 29  ? 0.44274 0.25287 0.43076 0.00057  0.07946  0.02851  52  THR A C   
401  O O   . THR A 29  ? 0.38744 0.17961 0.37074 0.00431  0.09013  0.03962  52  THR A O   
402  C CB  . THR A 29  ? 0.34259 0.18321 0.31983 -0.00134 0.06788  0.03266  52  THR A CB  
403  O OG1 . THR A 29  ? 0.32748 0.16827 0.32177 -0.01329 0.07178  0.02239  52  THR A OG1 
404  C CG2 . THR A 29  ? 0.34331 0.20581 0.31269 0.00083  0.05578  0.03225  52  THR A CG2 
412  N N   . ALA A 30  ? 0.38294 0.19180 0.38360 -0.00609 0.07897  0.01495  53  ALA A N   
413  C CA  . ALA A 30  ? 0.39873 0.18406 0.40955 -0.00902 0.09124  0.01211  53  ALA A CA  
414  C C   . ALA A 30  ? 0.40584 0.17358 0.40732 0.00388  0.09689  0.02360  53  ALA A C   
415  O O   . ALA A 30  ? 0.47190 0.21563 0.47564 0.00521  0.11003  0.03059  53  ALA A O   
416  C CB  . ALA A 30  ? 0.42303 0.21199 0.44661 -0.01740 0.08786  -0.00609 53  ALA A CB  
422  N N   . ASP A 31  ? 0.42728 0.20648 0.41939 0.01377  0.08759  0.02592  54  ASP A N   
423  C CA  . ASP A 31  ? 0.41582 0.18122 0.40209 0.02704  0.09156  0.03542  54  ASP A CA  
424  C C   . ASP A 31  ? 0.39660 0.17715 0.36874 0.03923  0.08216  0.04666  54  ASP A C   
425  O O   . ASP A 31  ? 0.41909 0.19336 0.38744 0.05166  0.08281  0.05415  54  ASP A O   
426  C CB  . ASP A 31  ? 0.46860 0.22923 0.46354 0.02746  0.09227  0.02361  54  ASP A CB  
427  C CG  . ASP A 31  ? 0.42080 0.20614 0.41461 0.02553  0.07977  0.01288  54  ASP A CG  
428  O OD1 . ASP A 31  ? 0.36074 0.16627 0.34874 0.02326  0.07043  0.01411  54  ASP A OD1 
429  O OD2 . ASP A 31  ? 0.49011 0.27327 0.48842 0.02647  0.08032  0.00327  54  ASP A OD2 
434  N N   . ASN A 32  ? 0.37312 0.17313 0.33865 0.03608  0.07376  0.04772  55  ASN A N   
435  C CA  . ASN A 32  ? 0.39077 0.20775 0.34412 0.04548  0.06386  0.05588  55  ASN A CA  
436  C C   . ASN A 32  ? 0.41059 0.24212 0.36710 0.05077  0.05545  0.05008  55  ASN A C   
437  O O   . ASN A 32  ? 0.45272 0.29289 0.40328 0.06171  0.04981  0.05738  55  ASN A O   
438  C CB  . ASN A 32  ? 0.44218 0.24623 0.38301 0.05756  0.06839  0.07262  55  ASN A CB  
439  C CG  . ASN A 32  ? 0.40772 0.22967 0.33434 0.06311  0.05878  0.07995  55  ASN A CG  
440  O OD1 . ASN A 32  ? 0.44624 0.28466 0.37231 0.05538  0.05264  0.07397  55  ASN A OD1 
441  N ND2 . ASN A 32  ? 0.53095 0.35007 0.44626 0.07707  0.05693  0.09244  55  ASN A ND2 
448  N N   . SER A 33  ? 0.38269 0.21785 0.34865 0.04318  0.05466  0.03661  56  SER A N   
449  C CA  . SER A 33  ? 0.42298 0.27123 0.39159 0.04718  0.04870  0.03048  56  SER A CA  
450  C C   . SER A 33  ? 0.41370 0.28562 0.37937 0.04192  0.03837  0.02571  56  SER A C   
451  O O   . SER A 33  ? 0.34976 0.22690 0.31329 0.03416  0.03593  0.02458  56  SER A O   
452  C CB  . SER A 33  ? 0.36812 0.20607 0.34562 0.04301  0.05433  0.01843  56  SER A CB  
453  O OG  . SER A 33  ? 0.40159 0.24161 0.38263 0.02992  0.05360  0.00706  56  SER A OG  
459  N N   . GLN A 34  ? 0.37385 0.25966 0.34060 0.04643  0.03321  0.02297  57  GLN A N   
460  C CA  . GLN A 34  ? 0.25436 0.16067 0.21903 0.04184  0.02488  0.01866  57  GLN A CA  
461  C C   . GLN A 34  ? 0.34835 0.26037 0.31684 0.04056  0.02496  0.00902  57  GLN A C   
462  O O   . GLN A 34  ? 0.35390 0.25993 0.32694 0.04708  0.02959  0.00788  57  GLN A O   
463  C CB  . GLN A 34  ? 0.38207 0.30339 0.34349 0.04890  0.01825  0.02633  57  GLN A CB  
464  C CG  . GLN A 34  ? 0.44580 0.36500 0.39959 0.05094  0.01682  0.03573  57  GLN A CG  
465  C CD  . GLN A 34  ? 0.57136 0.50690 0.52216 0.05828  0.00913  0.04111  57  GLN A CD  
466  O OE1 . GLN A 34  ? 0.58694 0.53324 0.53271 0.05467  0.00374  0.04154  57  GLN A OE1 
467  N NE2 . GLN A 34  ? 0.72974 0.66803 0.68506 0.06875  0.00844  0.04432  57  GLN A NE2 
476  N N   . ILE A 35  ? 0.27982 0.20316 0.24566 0.03290  0.02029  0.00269  58  ILE A N   
477  C CA  . ILE A 35  ? 0.29840 0.23110 0.26406 0.03204  0.01946  -0.00440 58  ILE A CA  
478  C C   . ILE A 35  ? 0.25093 0.20155 0.21459 0.03140  0.01299  -0.00119 58  ILE A C   
479  O O   . ILE A 35  ? 0.26407 0.21921 0.22400 0.02595  0.00842  0.00020  58  ILE A O   
480  C CB  . ILE A 35  ? 0.32504 0.25294 0.28737 0.02372  0.02035  -0.01493 58  ILE A CB  
481  C CG1 . ILE A 35  ? 0.34066 0.25063 0.30726 0.02437  0.02768  -0.01980 58  ILE A CG1 
482  C CG2 . ILE A 35  ? 0.35306 0.29093 0.31105 0.02295  0.01961  -0.02072 58  ILE A CG2 
483  C CD1 . ILE A 35  ? 0.47930 0.38370 0.44416 0.01545  0.02773  -0.03106 58  ILE A CD1 
495  N N   . LEU A 36  ? 0.27002 0.23077 0.23803 0.03697  0.01321  -0.00039 59  LEU A N   
496  C CA  . LEU A 36  ? 0.28996 0.26739 0.25927 0.03662  0.00799  0.00248  59  LEU A CA  
497  C C   . LEU A 36  ? 0.27780 0.26464 0.24901 0.03506  0.01033  -0.00285 59  LEU A C   
498  O O   . LEU A 36  ? 0.30976 0.29464 0.28519 0.03929  0.01588  -0.00632 59  LEU A O   
499  C CB  . LEU A 36  ? 0.30843 0.29256 0.28376 0.04517  0.00533  0.00942  59  LEU A CB  
500  C CG  . LEU A 36  ? 0.30071 0.27419 0.27216 0.04914  0.00457  0.01658  59  LEU A CG  
501  C CD1 . LEU A 36  ? 0.34065 0.32138 0.31677 0.05991  0.00161  0.02324  59  LEU A CD1 
502  C CD2 . LEU A 36  ? 0.29875 0.27311 0.26292 0.04218  0.00057  0.01816  59  LEU A CD2 
514  N N   . TYR A 37  ? 0.23222 0.22842 0.20044 0.02926  0.00719  -0.00322 60  TYR A N   
515  C CA  . TYR A 37  ? 0.20225 0.20671 0.17124 0.02721  0.01076  -0.00696 60  TYR A CA  
516  C C   . TYR A 37  ? 0.21193 0.22937 0.18491 0.02420  0.00672  -0.00390 60  TYR A C   
517  O O   . TYR A 37  ? 0.21576 0.23157 0.18258 0.01906  0.00262  -0.00227 60  TYR A O   
518  C CB  . TYR A 37  ? 0.22643 0.22309 0.18312 0.02161  0.01324  -0.01220 60  TYR A CB  
519  C CG  . TYR A 37  ? 0.25060 0.25353 0.20571 0.02061  0.01908  -0.01525 60  TYR A CG  
520  C CD1 . TYR A 37  ? 0.28118 0.28192 0.23825 0.02462  0.02655  -0.02018 60  TYR A CD1 
521  C CD2 . TYR A 37  ? 0.23800 0.24828 0.19037 0.01587  0.01855  -0.01300 60  TYR A CD2 
522  C CE1 . TYR A 37  ? 0.31727 0.32374 0.27287 0.02380  0.03360  -0.02288 60  TYR A CE1 
523  C CE2 . TYR A 37  ? 0.28840 0.30348 0.23953 0.01485  0.02598  -0.01495 60  TYR A CE2 
524  C CZ  . TYR A 37  ? 0.37018 0.38376 0.32252 0.01874  0.03359  -0.01991 60  TYR A CZ  
525  O OH  . TYR A 37  ? 0.28172 0.29973 0.23223 0.01767  0.04265  -0.02200 60  TYR A OH  
535  N N   . ARG A 38  ? 0.18757 0.21823 0.17274 0.02748  0.00778  -0.00370 61  ARG A N   
536  C CA  . ARG A 38  ? 0.16821 0.21192 0.16010 0.02433  0.00372  -0.00219 61  ARG A CA  
537  C C   . ARG A 38  ? 0.24354 0.28530 0.23132 0.02393  -0.00391 0.00156  61  ARG A C   
538  O O   . ARG A 38  ? 0.23272 0.27858 0.21959 0.01862  -0.00700 0.00180  61  ARG A O   
539  C CB  . ARG A 38  ? 0.20419 0.24853 0.19140 0.01644  0.00721  -0.00381 61  ARG A CB  
540  C CG  . ARG A 38  ? 0.22613 0.27333 0.21600 0.01617  0.01629  -0.00716 61  ARG A CG  
541  C CD  . ARG A 38  ? 0.21989 0.26828 0.20582 0.00876  0.02037  -0.00684 61  ARG A CD  
542  N NE  . ARG A 38  ? 0.25622 0.30427 0.23980 0.00823  0.03056  -0.00936 61  ARG A NE  
543  C CZ  . ARG A 38  ? 0.23835 0.29773 0.23696 0.01045  0.03722  -0.01210 61  ARG A CZ  
544  N NH1 . ARG A 38  ? 0.26189 0.33587 0.28050 0.01346  0.03355  -0.01279 61  ARG A NH1 
545  N NH2 . ARG A 38  ? 0.28260 0.33941 0.27600 0.01015  0.04774  -0.01459 61  ARG A NH2 
559  N N   . ALA A 39  ? 0.25619 0.29041 0.24111 0.02958  -0.00583 0.00451  62  ALA A N   
560  C CA  . ALA A 39  ? 0.19419 0.22324 0.17201 0.02896  -0.01084 0.00830  62  ALA A CA  
561  C C   . ALA A 39  ? 0.24185 0.28402 0.22438 0.03101  -0.01711 0.01001  62  ALA A C   
562  O O   . ALA A 39  ? 0.21682 0.25602 0.19216 0.02969  -0.02082 0.01237  62  ALA A O   
563  C CB  . ALA A 39  ? 0.19232 0.20769 0.16553 0.03420  -0.00904 0.01151  62  ALA A CB  
569  N N   . ASP A 40  ? 0.19317 0.25045 0.18797 0.03425  -0.01835 0.00813  63  ASP A N   
570  C CA  . ASP A 40  ? 0.21807 0.29082 0.21892 0.03555  -0.02551 0.00766  63  ASP A CA  
571  C C   . ASP A 40  ? 0.24220 0.32668 0.25213 0.02737  -0.02513 0.00209  63  ASP A C   
572  O O   . ASP A 40  ? 0.24750 0.34687 0.26553 0.02707  -0.03088 -0.00064 63  ASP A O   
573  C CB  . ASP A 40  ? 0.18399 0.26806 0.19493 0.04607  -0.02889 0.00931  63  ASP A CB  
574  C CG  . ASP A 40  ? 0.31460 0.38546 0.31586 0.05489  -0.02915 0.01623  63  ASP A CG  
575  O OD1 . ASP A 40  ? 0.24415 0.30533 0.23169 0.05383  -0.03129 0.02001  63  ASP A OD1 
576  O OD2 . ASP A 40  ? 0.25511 0.32394 0.26272 0.06265  -0.02593 0.01789  63  ASP A OD2 
581  N N   . GLU A 41  ? 0.23599 0.31384 0.24439 0.02076  -0.01846 0.00022  64  GLU A N   
582  C CA  . GLU A 41  ? 0.21689 0.30199 0.23230 0.01257  -0.01652 -0.00371 64  GLU A CA  
583  C C   . GLU A 41  ? 0.23454 0.31136 0.23975 0.00681  -0.01911 -0.00304 64  GLU A C   
584  O O   . GLU A 41  ? 0.22267 0.28677 0.21519 0.00789  -0.02005 0.00025  64  GLU A O   
585  C CB  . GLU A 41  ? 0.25033 0.33106 0.26651 0.00880  -0.00732 -0.00481 64  GLU A CB  
586  C CG  . GLU A 41  ? 0.18009 0.26836 0.20685 0.01447  -0.00289 -0.00631 64  GLU A CG  
587  C CD  . GLU A 41  ? 0.24903 0.33467 0.27612 0.01010  0.00746  -0.00810 64  GLU A CD  
588  O OE1 . GLU A 41  ? 0.20394 0.28442 0.22538 0.00257  0.01058  -0.00770 64  GLU A OE1 
589  O OE2 . GLU A 41  ? 0.23674 0.32508 0.26942 0.01471  0.01302  -0.00964 64  GLU A OE2 
596  N N   . ARG A 42  ? 0.17771 0.26198 0.19038 0.00051  -0.01969 -0.00680 65  ARG A N   
597  C CA  . ARG A 42  ? 0.20546 0.28183 0.21045 -0.00479 -0.02123 -0.00696 65  ARG A CA  
598  C C   . ARG A 42  ? 0.19070 0.25451 0.18974 -0.00995 -0.01459 -0.00493 65  ARG A C   
599  O O   . ARG A 42  ? 0.17754 0.24286 0.18196 -0.01259 -0.00829 -0.00540 65  ARG A O   
600  C CB  . ARG A 42  ? 0.17732 0.26589 0.19310 -0.00933 -0.02465 -0.01288 65  ARG A CB  
601  C CG  . ARG A 42  ? 0.19999 0.29919 0.21548 -0.00382 -0.03359 -0.01457 65  ARG A CG  
602  C CD  . ARG A 42  ? 0.24440 0.35453 0.26750 -0.00902 -0.03814 -0.02207 65  ARG A CD  
603  N NE  . ARG A 42  ? 0.26223 0.38182 0.28023 -0.00262 -0.04756 -0.02311 65  ARG A NE  
604  C CZ  . ARG A 42  ? 0.21045 0.32130 0.21202 -0.00039 -0.05053 -0.02087 65  ARG A CZ  
605  N NH1 . ARG A 42  ? 0.17853 0.27286 0.17037 -0.00421 -0.04543 -0.01844 65  ARG A NH1 
606  N NH2 . ARG A 42  ? 0.22320 0.34245 0.21790 0.00637  -0.05856 -0.02079 65  ARG A NH2 
620  N N   . PHE A 43  ? 0.18004 0.23201 0.16795 -0.01091 -0.01587 -0.00246 66  PHE A N   
621  C CA  . PHE A 43  ? 0.21071 0.25103 0.19185 -0.01458 -0.01175 0.00008  66  PHE A CA  
622  C C   . PHE A 43  ? 0.20335 0.23884 0.18284 -0.01763 -0.01403 -0.00062 66  PHE A C   
623  O O   . PHE A 43  ? 0.20060 0.23712 0.17758 -0.01553 -0.01859 -0.00158 66  PHE A O   
624  C CB  . PHE A 43  ? 0.22456 0.25524 0.19430 -0.01114 -0.01160 0.00351  66  PHE A CB  
625  C CG  . PHE A 43  ? 0.22967 0.26221 0.19916 -0.00820 -0.00827 0.00341  66  PHE A CG  
626  C CD1 . PHE A 43  ? 0.19756 0.23645 0.17192 -0.00336 -0.00998 0.00228  66  PHE A CD1 
627  C CD2 . PHE A 43  ? 0.22937 0.25662 0.19273 -0.00964 -0.00298 0.00463  66  PHE A CD2 
628  C CE1 . PHE A 43  ? 0.24298 0.28300 0.21851 -0.00010 -0.00601 0.00153  66  PHE A CE1 
629  C CE2 . PHE A 43  ? 0.23651 0.26523 0.19895 -0.00689 0.00118  0.00341  66  PHE A CE2 
630  C CZ  . PHE A 43  ? 0.21092 0.24581 0.18041 -0.00221 -0.00011 0.00147  66  PHE A CZ  
640  N N   . ALA A 44  ? 0.17810 0.20678 0.15785 -0.02199 -0.01003 0.00038  67  ALA A N   
641  C CA  . ALA A 44  ? 0.19255 0.21447 0.17097 -0.02403 -0.01122 -0.00011 67  ALA A CA  
642  C C   . ALA A 44  ? 0.20968 0.22428 0.17873 -0.02010 -0.01426 0.00314  67  ALA A C   
643  O O   . ALA A 44  ? 0.20542 0.21460 0.16794 -0.01806 -0.01360 0.00695  67  ALA A O   
644  C CB  . ALA A 44  ? 0.27809 0.29192 0.25877 -0.02845 -0.00534 0.00162  67  ALA A CB  
650  N N   . MET A 45  ? 0.18080 0.19597 0.14941 -0.01925 -0.01742 0.00096  68  MET A N   
651  C CA  . MET A 45  ? 0.17241 0.18265 0.13511 -0.01596 -0.01940 0.00332  68  MET A CA  
652  C C   . MET A 45  ? 0.17323 0.17499 0.13486 -0.01615 -0.01850 0.00586  68  MET A C   
653  O O   . MET A 45  ? 0.20258 0.20150 0.16108 -0.01367 -0.02019 0.00806  68  MET A O   
654  C CB  . MET A 45  ? 0.17624 0.18904 0.13791 -0.01495 -0.02135 0.00067  68  MET A CB  
655  C CG  . MET A 45  ? 0.18948 0.20985 0.14938 -0.01228 -0.02365 -0.00012 68  MET A CG  
656  S SD  . MET A 45  ? 0.21174 0.23327 0.16585 -0.01077 -0.02523 -0.00237 68  MET A SD  
657  C CE  . MET A 45  ? 0.19555 0.22316 0.15498 -0.01538 -0.02635 -0.00954 68  MET A CE  
667  N N   . CYS A 46  ? 0.21044 0.20821 0.17576 -0.01884 -0.01598 0.00534  69  CYS A N   
668  C CA  . CYS A 46  ? 0.23193 0.22123 0.19732 -0.01763 -0.01537 0.00813  69  CYS A CA  
669  C C   . CYS A 46  ? 0.22950 0.21929 0.19562 -0.01504 -0.01781 0.00698  69  CYS A C   
670  O O   . CYS A 46  ? 0.19634 0.19004 0.16315 -0.01566 -0.01790 0.00312  69  CYS A O   
671  C CB  . CYS A 46  ? 0.21129 0.19592 0.17083 -0.01559 -0.01523 0.01394  69  CYS A CB  
672  S SG  . CYS A 46  ? 0.23107 0.21401 0.19060 -0.01960 -0.00910 0.01539  69  CYS A SG  
678  N N   . SER A 47  ? 0.20289 0.18930 0.16901 -0.01199 -0.01959 0.01018  70  SER A N   
679  C CA  . SER A 47  ? 0.20329 0.19084 0.17398 -0.01019 -0.02048 0.00841  70  SER A CA  
680  C C   . SER A 47  ? 0.19412 0.18693 0.16322 -0.01020 -0.02135 0.00664  70  SER A C   
681  O O   . SER A 47  ? 0.22311 0.21678 0.19622 -0.00963 -0.02012 0.00486  70  SER A O   
682  C CB  . SER A 47  ? 0.19334 0.17880 0.16727 -0.00646 -0.02328 0.01168  70  SER A CB  
683  O OG  . SER A 47  ? 0.18965 0.16799 0.16586 -0.00527 -0.02140 0.01406  70  SER A OG  
688  N N   . THR A 48  ? 0.19546 0.19090 0.15941 -0.01068 -0.02222 0.00715  71  THR A N   
689  C CA  . THR A 48  ? 0.17981 0.17757 0.14247 -0.01018 -0.02184 0.00618  71  THR A CA  
690  C C   . THR A 48  ? 0.19262 0.19150 0.15379 -0.01063 -0.01947 0.00411  71  THR A C   
691  O O   . THR A 48  ? 0.19305 0.19168 0.15246 -0.00976 -0.01771 0.00427  71  THR A O   
692  C CB  . THR A 48  ? 0.23286 0.23211 0.19102 -0.00960 -0.02267 0.00707  71  THR A CB  
693  O OG1 . THR A 48  ? 0.20670 0.20897 0.16282 -0.01014 -0.02218 0.00676  71  THR A OG1 
694  C CG2 . THR A 48  ? 0.21801 0.21600 0.17491 -0.00911 -0.02492 0.00804  71  THR A CG2 
702  N N   . SER A 49  ? 0.18856 0.18802 0.14982 -0.01216 -0.01898 0.00189  72  SER A N   
703  C CA  . SER A 49  ? 0.19207 0.19335 0.15013 -0.01265 -0.01760 -0.00156 72  SER A CA  
704  C C   . SER A 49  ? 0.21689 0.21488 0.17659 -0.01215 -0.01419 -0.00296 72  SER A C   
705  O O   . SER A 49  ? 0.21541 0.21414 0.16932 -0.01186 -0.01211 -0.00532 72  SER A O   
706  C CB  . SER A 49  ? 0.22070 0.22377 0.18056 -0.01548 -0.01800 -0.00556 72  SER A CB  
707  O OG  . SER A 49  ? 0.23543 0.23263 0.20138 -0.01701 -0.01596 -0.00617 72  SER A OG  
713  N N   . LYS A 50  ? 0.19895 0.19412 0.16617 -0.01152 -0.01354 -0.00159 73  LYS A N   
714  C CA  . LYS A 50  ? 0.21841 0.21195 0.19055 -0.01083 -0.00951 -0.00352 73  LYS A CA  
715  C C   . LYS A 50  ? 0.19779 0.19220 0.16685 -0.01035 -0.00621 -0.00262 73  LYS A C   
716  O O   . LYS A 50  ? 0.21035 0.20367 0.17987 -0.01024 -0.00083 -0.00476 73  LYS A O   
717  C CB  . LYS A 50  ? 0.21586 0.20836 0.19896 -0.00924 -0.01091 -0.00199 73  LYS A CB  
718  C CG  . LYS A 50  ? 0.24953 0.23774 0.23467 -0.00909 -0.01194 -0.00185 73  LYS A CG  
719  C CD  . LYS A 50  ? 0.20586 0.19260 0.19842 -0.00588 -0.01491 0.00183  73  LYS A CD  
720  C CE  . LYS A 50  ? 0.23002 0.20908 0.22367 -0.00544 -0.01360 0.00286  73  LYS A CE  
721  N NZ  . LYS A 50  ? 0.24485 0.22017 0.23968 -0.00179 -0.01696 0.00886  73  LYS A NZ  
735  N N   . VAL A 51  ? 0.24845 0.24363 0.21441 -0.01006 -0.00809 0.00051  74  VAL A N   
736  C CA  . VAL A 51  ? 0.24439 0.23779 0.20672 -0.00968 -0.00373 0.00230  74  VAL A CA  
737  C C   . VAL A 51  ? 0.20622 0.19865 0.15575 -0.00856 -0.00089 0.00196  74  VAL A C   
738  O O   . VAL A 51  ? 0.21182 0.20147 0.15776 -0.00827 0.00547  0.00229  74  VAL A O   
739  C CB  . VAL A 51  ? 0.24384 0.23639 0.20500 -0.00929 -0.00598 0.00534  74  VAL A CB  
740  C CG1 . VAL A 51  ? 0.24395 0.23191 0.19940 -0.00847 -0.00039 0.00824  74  VAL A CG1 
741  C CG2 . VAL A 51  ? 0.19380 0.18780 0.16639 -0.01057 -0.00857 0.00437  74  VAL A CG2 
751  N N   A MET A 52  ? 0.19536 0.19075 0.13755 -0.00787 -0.00548 0.00110  75  MET A N   
752  N N   B MET A 52  ? 0.19477 0.19016 0.13705 -0.00790 -0.00547 0.00104  75  MET A N   
753  C CA  A MET A 52  ? 0.22274 0.21927 0.15151 -0.00619 -0.00484 0.00007  75  MET A CA  
754  C CA  B MET A 52  ? 0.22248 0.21899 0.15130 -0.00618 -0.00482 0.00011  75  MET A CA  
755  C C   A MET A 52  ? 0.25136 0.24680 0.17860 -0.00752 -0.00074 -0.00519 75  MET A C   
756  C C   B MET A 52  ? 0.25154 0.24710 0.17863 -0.00751 -0.00088 -0.00525 75  MET A C   
757  O O   A MET A 52  ? 0.25456 0.24817 0.17022 -0.00603 0.00361  -0.00535 75  MET A O   
758  O O   B MET A 52  ? 0.25474 0.24870 0.16986 -0.00599 0.00315  -0.00554 75  MET A O   
759  C CB  A MET A 52  ? 0.24045 0.24339 0.16540 -0.00550 -0.01165 -0.00137 75  MET A CB  
760  C CB  B MET A 52  ? 0.24017 0.24300 0.16506 -0.00540 -0.01161 -0.00112 75  MET A CB  
761  C CG  A MET A 52  ? 0.32749 0.33426 0.23750 -0.00242 -0.01362 -0.00209 75  MET A CG  
762  C CG  B MET A 52  ? 0.34208 0.34800 0.25197 -0.00181 -0.01329 -0.00051 75  MET A CG  
763  S SD  A MET A 52  ? 0.32976 0.33325 0.22740 0.00387  -0.01263 0.00678  75  MET A SD  
764  S SD  B MET A 52  ? 0.29502 0.29667 0.19680 0.00378  -0.01199 0.00873  75  MET A SD  
765  C CE  A MET A 52  ? 0.19173 0.18914 0.10304 0.00230  -0.00977 0.01101  75  MET A CE  
766  C CE  B MET A 52  ? 0.21711 0.22603 0.12720 0.00491  -0.01925 0.00913  75  MET A CE  
785  N N   . ALA A 53  ? 0.23706 0.23244 0.17507 -0.00983 -0.00123 -0.00924 76  ALA A N   
786  C CA  . ALA A 53  ? 0.23271 0.22595 0.17093 -0.01080 0.00340  -0.01513 76  ALA A CA  
787  C C   . ALA A 53  ? 0.20286 0.19284 0.14399 -0.00992 0.01144  -0.01394 76  ALA A C   
788  O O   . ALA A 53  ? 0.21848 0.20665 0.15101 -0.00950 0.01739  -0.01715 76  ALA A O   
789  C CB  . ALA A 53  ? 0.21972 0.21145 0.17017 -0.01265 0.00190  -0.01857 76  ALA A CB  
796  N N   . ALA A 54  ? 0.22780 0.21771 0.18169 -0.00989 0.01204  -0.01019 77  ALA A N   
797  C CA  . ALA A 54  ? 0.23716 0.22579 0.19726 -0.00983 0.02013  -0.00948 77  ALA A CA  
798  C C   . ALA A 54  ? 0.25389 0.23933 0.19914 -0.00917 0.02571  -0.00599 77  ALA A C   
799  O O   . ALA A 54  ? 0.24417 0.22704 0.18654 -0.00918 0.03498  -0.00690 77  ALA A O   
800  C CB  . ALA A 54  ? 0.21158 0.20281 0.18878 -0.01039 0.01806  -0.00699 77  ALA A CB  
806  N N   . ALA A 55  ? 0.23277 0.21762 0.16840 -0.00805 0.02103  -0.00136 78  ALA A N   
807  C CA  . ALA A 55  ? 0.25140 0.23150 0.17154 -0.00605 0.02602  0.00366  78  ALA A CA  
808  C C   . ALA A 55  ? 0.22306 0.20265 0.12410 -0.00406 0.02817  0.00107  78  ALA A C   
809  O O   . ALA A 55  ? 0.25350 0.22789 0.14158 -0.00253 0.03646  0.00403  78  ALA A O   
810  C CB  . ALA A 55  ? 0.25160 0.23138 0.16688 -0.00404 0.01967  0.00887  78  ALA A CB  
816  N N   . ALA A 56  ? 0.24547 0.23013 0.14369 -0.00426 0.02105  -0.00469 79  ALA A N   
817  C CA  . ALA A 56  ? 0.27480 0.26027 0.15538 -0.00302 0.02200  -0.00970 79  ALA A CA  
818  C C   . ALA A 56  ? 0.25392 0.23527 0.13470 -0.00417 0.03293  -0.01391 79  ALA A C   
819  O O   . ALA A 56  ? 0.27857 0.25707 0.14023 -0.00223 0.03871  -0.01431 79  ALA A O   
820  C CB  . ALA A 56  ? 0.30399 0.29591 0.18693 -0.00467 0.01293  -0.01705 79  ALA A CB  
826  N N   . VAL A 57  ? 0.27928 0.26064 0.18096 -0.00668 0.03588  -0.01714 80  VAL A N   
827  C CA  . VAL A 57  ? 0.27392 0.25249 0.18037 -0.00729 0.04697  -0.02140 80  VAL A CA  
828  C C   . VAL A 57  ? 0.25211 0.22664 0.15532 -0.00679 0.05751  -0.01514 80  VAL A C   
829  O O   . VAL A 57  ? 0.27017 0.24093 0.16094 -0.00606 0.06782  -0.01659 80  VAL A O   
830  C CB  . VAL A 57  ? 0.29774 0.27828 0.22977 -0.00865 0.04649  -0.02500 80  VAL A CB  
831  C CG1 . VAL A 57  ? 0.28708 0.26622 0.22846 -0.00851 0.05847  -0.02864 80  VAL A CG1 
832  C CG2 . VAL A 57  ? 0.32830 0.30952 0.26143 -0.00938 0.03934  -0.03142 80  VAL A CG2 
842  N N   . LEU A 58  ? 0.27596 0.25042 0.18969 -0.00751 0.05588  -0.00836 81  LEU A N   
843  C CA  . LEU A 58  ? 0.25241 0.22159 0.16475 -0.00801 0.06669  -0.00226 81  LEU A CA  
844  C C   . LEU A 58  ? 0.27498 0.23735 0.15768 -0.00483 0.07134  0.00267  81  LEU A C   
845  O O   . LEU A 58  ? 0.30460 0.26111 0.17938 -0.00485 0.08460  0.00484  81  LEU A O   
846  C CB  . LEU A 58  ? 0.27226 0.24173 0.19907 -0.00961 0.06267  0.00297  81  LEU A CB  
847  C CG  . LEU A 58  ? 0.24770 0.22339 0.20403 -0.01273 0.06212  -0.00064 81  LEU A CG  
848  C CD1 . LEU A 58  ? 0.25832 0.23474 0.22324 -0.01393 0.05468  0.00296  81  LEU A CD1 
849  C CD2 . LEU A 58  ? 0.29198 0.26767 0.26239 -0.01527 0.07600  -0.00207 81  LEU A CD2 
861  N N   B LYS A 59  ? 0.29305 0.25655 0.15908 -0.00164 0.06083  0.00477  82  LYS A N   
862  N N   C LYS A 59  ? 0.29299 0.25649 0.15901 -0.00163 0.06083  0.00475  82  LYS A N   
863  C CA  B LYS A 59  ? 0.34399 0.30239 0.18008 0.00301  0.06298  0.00988  82  LYS A CA  
864  C CA  C LYS A 59  ? 0.34402 0.30243 0.18014 0.00301  0.06297  0.00988  82  LYS A CA  
865  C C   B LYS A 59  ? 0.35748 0.31535 0.17694 0.00366  0.06963  0.00336  82  LYS A C   
866  C C   C LYS A 59  ? 0.35740 0.31528 0.17684 0.00367  0.06961  0.00337  82  LYS A C   
867  O O   B LYS A 59  ? 0.35742 0.30793 0.15664 0.00602  0.08028  0.00785  82  LYS A O   
868  O O   C LYS A 59  ? 0.35775 0.30825 0.15694 0.00603  0.08025  0.00786  82  LYS A O   
869  C CB  B LYS A 59  ? 0.32183 0.28540 0.14749 0.00670  0.04844  0.01133  82  LYS A CB  
870  C CB  C LYS A 59  ? 0.32214 0.28570 0.14780 0.00671  0.04845  0.01135  82  LYS A CB  
871  C CG  B LYS A 59  ? 0.38004 0.34143 0.17400 0.01304  0.04704  0.01579  82  LYS A CG  
872  C CG  C LYS A 59  ? 0.38047 0.34148 0.17460 0.01311  0.04727  0.01631  82  LYS A CG  
873  C CD  B LYS A 59  ? 0.46282 0.41237 0.24523 0.01672  0.05609  0.02861  82  LYS A CD  
874  C CD  C LYS A 59  ? 0.46231 0.41131 0.24630 0.01646  0.05667  0.02904  82  LYS A CD  
875  C CE  B LYS A 59  ? 0.57797 0.52532 0.32670 0.02482  0.05323  0.03454  82  LYS A CE  
876  C CE  C LYS A 59  ? 0.57898 0.52472 0.32894 0.02446  0.05513  0.03547  82  LYS A CE  
877  N NZ  B LYS A 59  ? 0.60223 0.53606 0.34003 0.02864  0.06314  0.04806  82  LYS A NZ  
878  N NZ  C LYS A 59  ? 0.63985 0.59508 0.38482 0.02955  0.03851  0.03578  82  LYS A NZ  
905  N N   . LYS A 60  ? 0.31258 0.27711 0.13892 0.00171  0.06405  -0.00734 83  LYS A N   
906  C CA  . LYS A 60  ? 0.35293 0.31668 0.16595 0.00172  0.07074  -0.01597 83  LYS A CA  
907  C C   . LYS A 60  ? 0.36443 0.32209 0.18296 0.00028  0.08816  -0.01505 83  LYS A C   
908  O O   . LYS A 60  ? 0.43067 0.38381 0.22804 0.00190  0.09816  -0.01693 83  LYS A O   
909  C CB  . LYS A 60  ? 0.32855 0.29840 0.15648 -0.00119 0.06343  -0.02759 83  LYS A CB  
910  C CG  . LYS A 60  ? 0.42352 0.39277 0.23820 -0.00152 0.06799  -0.03933 83  LYS A CG  
911  C CD  . LYS A 60  ? 0.45138 0.42462 0.28350 -0.00475 0.06042  -0.05005 83  LYS A CD  
912  C CE  . LYS A 60  ? 0.59421 0.56616 0.41352 -0.00566 0.06401  -0.06378 83  LYS A CE  
913  N NZ  . LYS A 60  ? 0.63092 0.59708 0.45728 -0.00580 0.07952  -0.06811 83  LYS A NZ  
927  N N   . SER A 61  ? 0.33968 0.29796 0.18668 -0.00277 0.09218  -0.01249 84  SER A N   
928  C CA  . SER A 61  ? 0.32812 0.28320 0.18683 -0.00481 0.10877  -0.01229 84  SER A CA  
929  C C   . SER A 61  ? 0.39973 0.34540 0.23883 -0.00356 0.12138  -0.00274 84  SER A C   
930  O O   . SER A 61  ? 0.40213 0.34412 0.24283 -0.00496 0.13774  -0.00349 84  SER A O   
931  C CB  . SER A 61  ? 0.31475 0.27510 0.20972 -0.00822 0.10760  -0.01195 84  SER A CB  
932  O OG  . SER A 61  ? 0.33580 0.29363 0.23641 -0.00943 0.10653  -0.00293 84  SER A OG  
938  N N   . GLU A 62  ? 0.37052 0.31154 0.19210 -0.00066 0.11530  0.00666  85  GLU A N   
939  C CA  . GLU A 62  ? 0.40681 0.33615 0.20811 0.00137  0.12803  0.01743  85  GLU A CA  
940  C C   . GLU A 62  ? 0.52214 0.44701 0.29356 0.00438  0.13777  0.01544  85  GLU A C   
941  O O   . GLU A 62  ? 0.56865 0.48773 0.33743 0.00407  0.14974  0.02101  85  GLU A O   
942  C CB  . GLU A 62  ? 0.38708 0.31197 0.17309 0.00581  0.11803  0.02780  85  GLU A CB  
943  C CG  . GLU A 62  ? 0.40586 0.33329 0.22105 0.00243  0.11137  0.02999  85  GLU A CG  
944  C CD  . GLU A 62  ? 0.44334 0.36725 0.24733 0.00708  0.10104  0.03868  85  GLU A CD  
945  O OE1 . GLU A 62  ? 0.54140 0.45919 0.31511 0.01358  0.10084  0.04577  85  GLU A OE1 
946  O OE2 . GLU A 62  ? 0.41228 0.33989 0.23820 0.00467  0.09317  0.03821  85  GLU A OE2 
953  N N   A SER A 63  ? 0.49059 0.42149 0.24680 0.00666  0.12858  0.00638  86  SER A N   
954  N N   B SER A 63  ? 0.49143 0.42237 0.24783 0.00662  0.12862  0.00625  86  SER A N   
955  C CA  A SER A 63  ? 0.56094 0.49314 0.29624 0.00901  0.13203  0.00211  86  SER A CA  
956  C CA  B SER A 63  ? 0.56188 0.49426 0.29704 0.00903  0.13168  0.00188  86  SER A CA  
957  C C   A SER A 63  ? 0.57977 0.51519 0.32673 0.00583  0.14030  -0.01137 86  SER A C   
958  C C   B SER A 63  ? 0.58012 0.51543 0.32732 0.00579  0.14066  -0.01126 86  SER A C   
959  O O   A SER A 63  ? 0.55711 0.49398 0.28737 0.00757  0.14355  -0.01681 86  SER A O   
960  O O   B SER A 63  ? 0.55909 0.49556 0.29013 0.00744  0.14470  -0.01635 86  SER A O   
961  C CB  A SER A 63  ? 0.53429 0.47288 0.24402 0.01377  0.11533  0.00028  86  SER A CB  
962  C CB  B SER A 63  ? 0.53582 0.47494 0.24652 0.01356  0.11465  -0.00076 86  SER A CB  
963  O OG  A SER A 63  ? 0.52885 0.47334 0.24693 0.01271  0.10213  -0.00723 86  SER A OG  
964  O OG  B SER A 63  ? 0.50755 0.44568 0.21210 0.01710  0.10467  0.01053  86  SER A OG  
975  N N   . GLU A 64  ? 0.43472 0.60952 0.44949 -0.08621 0.06662  0.16889  87  GLU A N   
976  C CA  . GLU A 64  ? 0.44349 0.60190 0.41178 -0.08437 0.08252  0.13594  87  GLU A CA  
977  C C   . GLU A 64  ? 0.41148 0.55086 0.42482 -0.06462 0.08512  0.12242  87  GLU A C   
978  O O   . GLU A 64  ? 0.43550 0.54359 0.45603 -0.05206 0.07798  0.09886  87  GLU A O   
979  C CB  . GLU A 64  ? 0.39649 0.52414 0.30664 -0.08567 0.07951  0.10689  87  GLU A CB  
980  C CG  . GLU A 64  ? 0.54352 0.67814 0.41688 -0.10121 0.06619  0.11422  87  GLU A CG  
981  C CD  . GLU A 64  ? 0.68229 0.78533 0.51127 -0.10069 0.05661  0.08870  87  GLU A CD  
982  O OE1 . GLU A 64  ? 0.59040 0.66290 0.39287 -0.09404 0.06786  0.05991  87  GLU A OE1 
983  O OE2 . GLU A 64  ? 0.65515 0.76668 0.48417 -0.10549 0.03771  0.09823  87  GLU A OE2 
990  N N   . PRO A 65  ? 0.47606 0.64208 0.51959 -0.06535 0.09404  0.14096  88  PRO A N   
991  C CA  . PRO A 65  ? 0.59207 0.75052 0.68462 -0.05416 0.09111  0.14069  88  PRO A CA  
992  C C   . PRO A 65  ? 0.53756 0.67819 0.61648 -0.03975 0.10278  0.11448  88  PRO A C   
993  O O   . PRO A 65  ? 0.59420 0.72745 0.71008 -0.03571 0.09393  0.11290  88  PRO A O   
994  C CB  . PRO A 65  ? 0.60225 0.80506 0.72204 -0.06094 0.09850  0.17315  88  PRO A CB  
995  C CG  . PRO A 65  ? 0.57964 0.81175 0.67275 -0.07618 0.10060  0.18954  88  PRO A CG  
996  C CD  . PRO A 65  ? 0.62938 0.84067 0.65976 -0.08035 0.10657  0.16509  88  PRO A CD  
1004 N N   . ASN A 66  ? 0.52830 0.66224 0.55636 -0.03461 0.12407  0.09679  89  ASN A N   
1005 C CA  . ASN A 66  ? 0.64706 0.76138 0.67111 -0.01751 0.13791  0.07661  89  ASN A CA  
1006 C C   . ASN A 66  ? 0.40103 0.48315 0.41590 -0.01595 0.11998  0.05262  89  ASN A C   
1007 O O   . ASN A 66  ? 0.40644 0.47770 0.42950 -0.00350 0.12678  0.04040  89  ASN A O   
1008 C CB  . ASN A 66  ? 0.72793 0.83197 0.69824 -0.01037 0.17319  0.06281  89  ASN A CB  
1009 C CG  . ASN A 66  ? 0.75060 0.89162 0.73399 -0.00510 0.19794  0.08539  89  ASN A CG  
1010 O OD1 . ASN A 66  ? 0.90724 1.08188 0.94946 0.00039  0.19159  0.11253  89  ASN A OD1 
1011 N ND2 . ASN A 66  ? 0.92807 1.06486 0.85211 -0.01034 0.22617  0.07498  89  ASN A ND2 
1018 N N   . LEU A 67  ? 0.32868 0.40206 0.33164 -0.02723 0.09843  0.05079  90  LEU A N   
1019 C CA  . LEU A 67  ? 0.31036 0.35854 0.28700 -0.02638 0.08515  0.02871  90  LEU A CA  
1020 C C   . LEU A 67  ? 0.26627 0.30903 0.28105 -0.01712 0.07513  0.01723  90  LEU A C   
1021 O O   . LEU A 67  ? 0.28507 0.31467 0.28428 -0.01075 0.07670  -0.00009 90  LEU A O   
1022 C CB  . LEU A 67  ? 0.31192 0.36238 0.28108 -0.03666 0.06518  0.03862  90  LEU A CB  
1023 C CG  . LEU A 67  ? 0.35909 0.39332 0.29450 -0.03752 0.05037  0.02231  90  LEU A CG  
1024 C CD1 . LEU A 67  ? 0.54925 0.56883 0.41643 -0.04706 0.06180  0.00880  90  LEU A CD1 
1025 C CD2 . LEU A 67  ? 0.37523 0.42093 0.31717 -0.04228 0.03353  0.04210  90  LEU A CD2 
1037 N N   . LEU A 68  ? 0.26813 0.32189 0.33177 -0.02072 0.06424  0.02824  91  LEU A N   
1038 C CA  . LEU A 68  ? 0.24296 0.29768 0.33631 -0.02210 0.05130  0.01803  91  LEU A CA  
1039 C C   . LEU A 68  ? 0.20554 0.27910 0.31740 -0.01399 0.06636  0.02297  91  LEU A C   
1040 O O   . LEU A 68  ? 0.24791 0.33026 0.37845 -0.01549 0.05727  0.01616  91  LEU A O   
1041 C CB  . LEU A 68  ? 0.22894 0.28362 0.35911 -0.03602 0.03836  0.02694  91  LEU A CB  
1042 C CG  . LEU A 68  ? 0.28298 0.31258 0.40603 -0.03861 0.02802  0.02331  91  LEU A CG  
1043 C CD1 . LEU A 68  ? 0.34195 0.35450 0.49693 -0.05353 0.02082  0.02721  91  LEU A CD1 
1044 C CD2 . LEU A 68  ? 0.27695 0.29480 0.37628 -0.03260 0.01739  0.00236  91  LEU A CD2 
1056 N N   . ASN A 69  ? 0.23030 0.31471 0.33978 -0.00448 0.09136  0.03786  92  ASN A N   
1057 C CA  . ASN A 69  ? 0.23173 0.33371 0.36311 0.01024  0.11388  0.04874  92  ASN A CA  
1058 C C   . ASN A 69  ? 0.30619 0.37735 0.39697 0.02605  0.13422  0.02862  92  ASN A C   
1059 O O   . ASN A 69  ? 0.26660 0.34470 0.37948 0.04307  0.15739  0.03765  92  ASN A O   
1060 C CB  . ASN A 69  ? 0.24906 0.37946 0.40051 0.01618  0.13572  0.07769  92  ASN A CB  
1061 C CG  . ASN A 69  ? 0.36974 0.53342 0.56889 -0.00229 0.11585  0.10378  92  ASN A CG  
1062 O OD1 . ASN A 69  ? 0.38739 0.56357 0.61578 -0.01612 0.09697  0.10633  92  ASN A OD1 
1063 N ND2 . ASN A 69  ? 0.45837 0.63714 0.66240 -0.00779 0.11833  0.12365  92  ASN A ND2 
1070 N N   . GLN A 70  ? 0.27430 0.31203 0.30813 0.01915  0.12689  0.00578  93  GLN A N   
1071 C CA  . GLN A 70  ? 0.32671 0.32574 0.31012 0.02621  0.14404  -0.01538 93  GLN A CA  
1072 C C   . GLN A 70  ? 0.31427 0.31232 0.32552 0.03345  0.13463  -0.02082 93  GLN A C   
1073 O O   . GLN A 70  ? 0.25237 0.26932 0.28825 0.02319  0.10213  -0.02208 93  GLN A O   
1074 C CB  . GLN A 70  ? 0.45230 0.42624 0.36881 0.00767  0.12962  -0.03158 93  GLN A CB  
1075 C CG  . GLN A 70  ? 0.69430 0.62095 0.54481 0.00471  0.14281  -0.05497 93  GLN A CG  
1076 C CD  . GLN A 70  ? 0.68142 0.59620 0.46608 -0.02186 0.12195  -0.06170 93  GLN A CD  
1077 O OE1 . GLN A 70  ? 0.69215 0.62989 0.46632 -0.03626 0.11554  -0.04749 93  GLN A OE1 
1078 N NE2 . GLN A 70  ? 0.77262 0.66735 0.53703 -0.02741 0.10199  -0.07103 93  GLN A NE2 
1087 N N   . ARG A 71  ? 0.38199 0.35664 0.38827 0.05104  0.16561  -0.02391 94  ARG A N   
1088 C CA  . ARG A 71  ? 0.36461 0.34407 0.40798 0.05972  0.16090  -0.02129 94  ARG A CA  
1089 C C   . ARG A 71  ? 0.44051 0.37761 0.42884 0.04960  0.14433  -0.04806 94  ARG A C   
1090 O O   . ARG A 71  ? 0.42548 0.31221 0.34062 0.04326  0.15783  -0.06780 94  ARG A O   
1091 C CB  . ARG A 71  ? 0.40951 0.38295 0.48133 0.08352  0.19739  -0.00363 94  ARG A CB  
1092 C CG  . ARG A 71  ? 0.37709 0.38773 0.48792 0.09242  0.21264  0.02745  94  ARG A CG  
1093 C CD  . ARG A 71  ? 0.31628 0.39453 0.49480 0.08018  0.18578  0.05544  94  ARG A CD  
1094 N NE  . ARG A 71  ? 0.25181 0.35657 0.47579 0.07663  0.16755  0.07007  94  ARG A NE  
1095 C CZ  . ARG A 71  ? 0.31487 0.47125 0.58200 0.05834  0.13977  0.09386  94  ARG A CZ  
1096 N NH1 . ARG A 71  ? 0.19940 0.38248 0.47545 0.04393  0.12894  0.10664  94  ARG A NH1 
1097 N NH2 . ARG A 71  ? 0.22335 0.39894 0.51416 0.05026  0.12044  0.10279  94  ARG A NH2 
1111 N N   . VAL A 72  ? 0.29506 0.25802 0.31895 0.04433  0.11406  -0.04524 95  VAL A N   
1112 C CA  . VAL A 72  ? 0.33927 0.27876 0.32469 0.03320  0.08974  -0.06287 95  VAL A CA  
1113 C C   . VAL A 72  ? 0.26276 0.21297 0.29917 0.04470  0.09290  -0.05193 95  VAL A C   
1114 O O   . VAL A 72  ? 0.24907 0.25957 0.35928 0.04527  0.07979  -0.03009 95  VAL A O   
1115 C CB  . VAL A 72  ? 0.35150 0.32548 0.33619 0.01471  0.04519  -0.06576 95  VAL A CB  
1116 C CG1 . VAL A 72  ? 0.41149 0.37426 0.36114 0.00369  0.01745  -0.07680 95  VAL A CG1 
1117 C CG2 . VAL A 72  ? 0.36581 0.33434 0.31532 0.00597  0.04452  -0.06765 95  VAL A CG2 
1127 N N   . GLU A 73  ? 0.31640 0.21017 0.31287 0.04897  0.10828  -0.06506 96  GLU A N   
1128 C CA  . GLU A 73  ? 0.32754 0.22714 0.37698 0.06137  0.11363  -0.05070 96  GLU A CA  
1129 C C   . GLU A 73  ? 0.26528 0.21870 0.34369 0.04343  0.06189  -0.04536 96  GLU A C   
1130 O O   . GLU A 73  ? 0.29962 0.24751 0.32424 0.02384  0.02882  -0.06247 96  GLU A O   
1131 C CB  . GLU A 73  ? 0.41140 0.22441 0.40107 0.06596  0.14093  -0.06912 96  GLU A CB  
1132 C CG  . GLU A 73  ? 0.61465 0.38882 0.56648 0.07248  0.17812  -0.07112 96  GLU A CG  
1133 C CD  . GLU A 73  ? 0.82675 0.60379 0.84033 0.09882  0.21580  -0.04465 96  GLU A CD  
1134 O OE1 . GLU A 73  ? 0.88455 0.69912 0.97246 0.10892  0.20983  -0.02007 96  GLU A OE1 
1135 O OE2 . GLU A 73  ? 0.80917 0.55660 0.79959 0.10751  0.25020  -0.04430 96  GLU A OE2 
1142 N N   . ILE A 74  ? 0.20234 0.21382 0.36725 0.04944  0.05639  -0.01719 97  ILE A N   
1143 C CA  . ILE A 74  ? 0.25211 0.32164 0.45069 0.03194  0.01082  -0.00954 97  ILE A CA  
1144 C C   . ILE A 74  ? 0.19205 0.24433 0.42032 0.04173  0.01929  0.00419  97  ILE A C   
1145 O O   . ILE A 74  ? 0.22371 0.29194 0.52270 0.06115  0.05068  0.03428  97  ILE A O   
1146 C CB  . ILE A 74  ? 0.12864 0.27388 0.36800 0.01842  -0.00616 0.01265  97  ILE A CB  
1147 C CG1 . ILE A 74  ? 0.22132 0.37271 0.44116 0.01170  -0.00654 0.00261  97  ILE A CG1 
1148 C CG2 . ILE A 74  ? 0.17261 0.33436 0.35303 0.00033  -0.03260 0.00543  97  ILE A CG2 
1149 C CD1 . ILE A 74  ? 0.24583 0.37669 0.40932 -0.00016 -0.03134 -0.02476 97  ILE A CD1 
1161 N N   . LYS A 75  ? 0.28544 0.30777 0.46412 0.02837  -0.00793 -0.01226 98  LYS A N   
1162 C CA  . LYS A 75  ? 0.37277 0.36785 0.57134 0.03378  -0.00380 -0.00126 98  LYS A CA  
1163 C C   . LYS A 75  ? 0.25064 0.33046 0.50000 0.01496  -0.05611 0.01741  98  LYS A C   
1164 O O   . LYS A 75  ? 0.22309 0.32795 0.39864 -0.00285 -0.07073 0.00709  98  LYS A O   
1165 C CB  . LYS A 75  ? 0.37068 0.25626 0.46291 0.02684  0.00661  -0.03319 98  LYS A CB  
1166 C CG  . LYS A 75  ? 0.45712 0.25744 0.48831 0.04079  0.06091  -0.05540 98  LYS A CG  
1167 C CD  . LYS A 75  ? 0.69258 0.39633 0.59782 0.01810  0.06268  -0.09077 98  LYS A CD  
1168 C CE  . LYS A 75  ? 0.78130 0.52173 0.62742 -0.01337 0.01122  -0.09990 98  LYS A CE  
1169 N NZ  . LYS A 75  ? 0.73049 0.51724 0.58384 -0.00997 0.01161  -0.09981 98  LYS A NZ  
1183 N N   . LYS A 76  ? 0.20055 0.28985 0.50735 0.02107  -0.05161 0.04393  99  LYS A N   
1184 C CA  . LYS A 76  ? 0.30202 0.41236 0.54856 -0.00020 -0.07100 0.04613  99  LYS A CA  
1185 C C   . LYS A 76  ? 0.27300 0.36546 0.43422 -0.01244 -0.08806 0.02151  99  LYS A C   
1186 O O   . LYS A 76  ? 0.23431 0.33150 0.36909 -0.02067 -0.09198 0.02528  99  LYS A O   
1187 C CB  . LYS A 76  ? 0.22279 0.32743 0.53865 0.00493  -0.06581 0.07645  99  LYS A CB  
1188 C CG  . LYS A 76  ? 0.30363 0.43978 0.63527 0.00443  -0.04870 0.09991  99  LYS A CG  
1189 C CD  . LYS A 76  ? 0.68662 0.81816 1.07892 0.00575  -0.04366 0.13384  99  LYS A CD  
1190 C CE  . LYS A 76  ? 0.67389 0.83166 1.10482 0.00231  -0.03119 0.17751  99  LYS A CE  
1191 N NZ  . LYS A 76  ? 0.77993 0.96227 1.16673 -0.01794 -0.05387 0.18609  99  LYS A NZ  
1205 N N   . SER A 77  ? 0.25453 0.29130 0.40620 -0.01866 -0.11550 0.00798  100 SER A N   
1206 C CA  . SER A 77  ? 0.26967 0.28939 0.32423 -0.02989 -0.11034 -0.00549 100 SER A CA  
1207 C C   . SER A 77  ? 0.30116 0.33899 0.32799 -0.02692 -0.09566 -0.00988 100 SER A C   
1208 O O   . SER A 77  ? 0.27823 0.30674 0.27691 -0.03119 -0.09692 -0.00629 100 SER A O   
1209 C CB  . SER A 77  ? 0.36394 0.27955 0.34750 -0.04607 -0.12862 -0.02766 100 SER A CB  
1210 O OG  . SER A 77  ? 0.46049 0.31154 0.41358 -0.03763 -0.09571 -0.05202 100 SER A OG  
1216 N N   . ASP A 78  ? 0.25907 0.31808 0.30355 -0.02177 -0.08545 -0.01358 101 ASP A N   
1217 C CA  . ASP A 78  ? 0.26232 0.33277 0.28961 -0.02090 -0.07631 -0.01661 101 ASP A CA  
1218 C C   . ASP A 78  ? 0.26684 0.36384 0.31091 -0.01706 -0.07352 -0.01324 101 ASP A C   
1219 O O   . ASP A 78  ? 0.21228 0.30432 0.24541 -0.01226 -0.06900 -0.01907 101 ASP A O   
1220 C CB  . ASP A 78  ? 0.19882 0.26920 0.23181 -0.02081 -0.06965 -0.02014 101 ASP A CB  
1221 C CG  . ASP A 78  ? 0.25503 0.27794 0.24945 -0.02451 -0.07112 -0.04053 101 ASP A CG  
1222 O OD1 . ASP A 78  ? 0.28812 0.29816 0.24200 -0.02989 -0.06492 -0.04477 101 ASP A OD1 
1223 O OD2 . ASP A 78  ? 0.34733 0.33615 0.36444 -0.00987 -0.06480 -0.05892 101 ASP A OD2 
1228 N N   . LEU A 79  ? 0.32195 0.16713 0.23900 -0.04014 0.01865  0.01770  102 LEU A N   
1229 C CA  . LEU A 79  ? 0.34921 0.19143 0.25481 -0.03480 0.00705  0.02854  102 LEU A CA  
1230 C C   . LEU A 79  ? 0.35474 0.21569 0.24722 -0.06098 0.01850  0.01485  102 LEU A C   
1231 O O   . LEU A 79  ? 0.34977 0.20407 0.22963 -0.08736 0.03971  -0.00188 102 LEU A O   
1232 C CB  . LEU A 79  ? 0.40494 0.18463 0.27528 -0.01935 0.00521  0.04533  102 LEU A CB  
1233 C CG  . LEU A 79  ? 0.41681 0.19876 0.31482 0.01303  -0.01050 0.05399  102 LEU A CG  
1234 C CD1 . LEU A 79  ? 0.47795 0.20389 0.33546 0.03895  -0.01882 0.07061  102 LEU A CD1 
1235 C CD2 . LEU A 79  ? 0.51799 0.35949 0.46260 0.02202  -0.02992 0.05106  102 LEU A CD2 
1247 N N   . VAL A 80  ? 0.34662 0.23716 0.24729 -0.05596 0.00722  0.01674  103 VAL A N   
1248 C CA  . VAL A 80  ? 0.31822 0.23102 0.21170 -0.07711 0.01954  0.00215  103 VAL A CA  
1249 C C   . VAL A 80  ? 0.43844 0.31517 0.29795 -0.07419 0.01647  0.01573  103 VAL A C   
1250 O O   . VAL A 80  ? 0.49607 0.31204 0.31575 -0.06753 0.01525  0.03201  103 VAL A O   
1251 C CB  . VAL A 80  ? 0.33247 0.31802 0.26409 -0.06960 0.01156  -0.01277 103 VAL A CB  
1252 C CG1 . VAL A 80  ? 0.43188 0.45277 0.38111 -0.07776 0.01583  -0.03163 103 VAL A CG1 
1253 C CG2 . VAL A 80  ? 0.26907 0.26099 0.21451 -0.04087 -0.00719 0.00146  103 VAL A CG2 
1263 N N   . ASN A 81  ? 0.42907 0.33858 0.29706 -0.07502 0.01458  0.00914  104 ASN A N   
1264 C CA  . ASN A 81  ? 0.41429 0.28800 0.23997 -0.07987 0.01760  0.01639  104 ASN A CA  
1265 C C   . ASN A 81  ? 0.43172 0.30827 0.25986 -0.05773 -0.00711 0.02780  104 ASN A C   
1266 O O   . ASN A 81  ? 0.51120 0.36330 0.30159 -0.06090 -0.00792 0.03122  104 ASN A O   
1267 C CB  . ASN A 81  ? 0.38824 0.29269 0.21704 -0.10293 0.04100  -0.00528 104 ASN A CB  
1268 C CG  . ASN A 81  ? 0.44784 0.42300 0.32741 -0.08696 0.03180  -0.01808 104 ASN A CG  
1269 O OD1 . ASN A 81  ? 0.39645 0.39272 0.30394 -0.06478 0.01395  -0.01235 104 ASN A OD1 
1270 N ND2 . ASN A 81  ? 0.51088 0.51643 0.39680 -0.09598 0.04749  -0.03577 104 ASN A ND2 
1277 N N   . TYR A 82  ? 0.33552 0.23933 0.20298 -0.03989 -0.02334 0.03009  105 TYR A N   
1278 C CA  . TYR A 82  ? 0.36688 0.27792 0.24255 -0.02789 -0.04012 0.03251  105 TYR A CA  
1279 C C   . TYR A 82  ? 0.30943 0.23778 0.22451 -0.01540 -0.04833 0.03357  105 TYR A C   
1280 O O   . TYR A 82  ? 0.27206 0.21986 0.20915 -0.01165 -0.04045 0.02821  105 TYR A O   
1281 C CB  . TYR A 82  ? 0.30613 0.23612 0.18501 -0.03075 -0.03150 0.02182  105 TYR A CB  
1282 C CG  . TYR A 82  ? 0.31948 0.24243 0.19214 -0.02798 -0.04349 0.02025  105 TYR A CG  
1283 C CD1 . TYR A 82  ? 0.39952 0.30034 0.23330 -0.03298 -0.05498 0.02272  105 TYR A CD1 
1284 C CD2 . TYR A 82  ? 0.34039 0.27347 0.23855 -0.02211 -0.04195 0.01444  105 TYR A CD2 
1285 C CE1 . TYR A 82  ? 0.48682 0.39090 0.31600 -0.03426 -0.06838 0.01482  105 TYR A CE1 
1286 C CE2 . TYR A 82  ? 0.35950 0.28733 0.25390 -0.02819 -0.04833 0.00599  105 TYR A CE2 
1287 C CZ  . TYR A 82  ? 0.38728 0.30834 0.25200 -0.03518 -0.06383 0.00389  105 TYR A CZ  
1288 O OH  . TYR A 82  ? 0.40056 0.32653 0.26263 -0.04469 -0.07292 -0.01108 105 TYR A OH  
1298 N N   . ASN A 83  ? 0.31020 0.22930 0.22986 -0.00591 -0.06283 0.03980  106 ASN A N   
1299 C CA  . ASN A 83  ? 0.29639 0.23035 0.25486 0.00293  -0.06400 0.03824  106 ASN A CA  
1300 C C   . ASN A 83  ? 0.26516 0.21915 0.24840 0.01140  -0.08221 0.03243  106 ASN A C   
1301 O O   . ASN A 83  ? 0.31447 0.27585 0.31847 0.02573  -0.09136 0.03316  106 ASN A O   
1302 C CB  . ASN A 83  ? 0.44359 0.35585 0.39505 0.00794  -0.05867 0.04504  106 ASN A CB  
1303 C CG  . ASN A 83  ? 0.40870 0.29646 0.32377 -0.00682 -0.04337 0.04622  106 ASN A CG  
1304 O OD1 . ASN A 83  ? 0.34330 0.25317 0.26595 -0.01867 -0.03150 0.03686  106 ASN A OD1 
1305 N ND2 . ASN A 83  ? 0.48740 0.32900 0.36036 -0.00531 -0.04191 0.05548  106 ASN A ND2 
1312 N N   . PRO A 84  ? 0.28108 0.24875 0.26448 0.00286  -0.08763 0.02247  107 PRO A N   
1313 C CA  . PRO A 84  ? 0.29011 0.29032 0.29823 0.00660  -0.10896 0.00913  107 PRO A CA  
1314 C C   . PRO A 84  ? 0.23868 0.27384 0.30644 0.00811  -0.10468 -0.00446 107 PRO A C   
1315 O O   . PRO A 84  ? 0.29075 0.36578 0.39011 0.02070  -0.12654 -0.01573 107 PRO A O   
1316 C CB  . PRO A 84  ? 0.37151 0.37414 0.36799 -0.01263 -0.10435 -0.00476 107 PRO A CB  
1317 C CG  . PRO A 84  ? 0.36167 0.33579 0.34390 -0.01991 -0.07580 0.00143  107 PRO A CG  
1318 C CD  . PRO A 84  ? 0.29851 0.25624 0.26122 -0.00976 -0.07407 0.01866  107 PRO A CD  
1326 N N   . ILE A 85  ? 0.22030 0.24389 0.30222 -0.00255 -0.07679 -0.00586 108 ILE A N   
1327 C CA  . ILE A 85  ? 0.23932 0.28601 0.37034 -0.00670 -0.06250 -0.02008 108 ILE A CA  
1328 C C   . ILE A 85  ? 0.23816 0.27410 0.37410 0.00988  -0.05826 -0.00807 108 ILE A C   
1329 O O   . ILE A 85  ? 0.20805 0.27338 0.38620 0.02065  -0.06212 -0.01773 108 ILE A O   
1330 C CB  . ILE A 85  ? 0.21090 0.23238 0.33595 -0.02808 -0.02845 -0.02792 108 ILE A CB  
1331 C CG1 . ILE A 85  ? 0.23063 0.25048 0.34680 -0.04818 -0.02466 -0.04366 108 ILE A CG1 
1332 C CG2 . ILE A 85  ? 0.21229 0.24790 0.37989 -0.03761 -0.00506 -0.04385 108 ILE A CG2 
1333 C CD1 . ILE A 85  ? 0.23559 0.31391 0.39716 -0.05868 -0.04391 -0.07085 108 ILE A CD1 
1345 N N   . ALA A 86  ? 0.25269 0.25111 0.34829 0.01162  -0.04918 0.00887  109 ALA A N   
1346 C CA  . ALA A 86  ? 0.21286 0.19556 0.30714 0.02021  -0.03965 0.01557  109 ALA A CA  
1347 C C   . ALA A 86  ? 0.28162 0.26089 0.37682 0.04055  -0.05667 0.02167  109 ALA A C   
1348 O O   . ALA A 86  ? 0.29430 0.27174 0.40970 0.05221  -0.04929 0.01928  109 ALA A O   
1349 C CB  . ALA A 86  ? 0.26326 0.21945 0.31647 0.01421  -0.02941 0.02501  109 ALA A CB  
1355 N N   . GLU A 87  ? 0.31580 0.28510 0.38069 0.04811  -0.07710 0.03024  110 GLU A N   
1356 C CA  . GLU A 87  ? 0.43491 0.38242 0.48116 0.07508  -0.09250 0.04037  110 GLU A CA  
1357 C C   . GLU A 87  ? 0.39223 0.38616 0.49419 0.10017  -0.10778 0.02765  110 GLU A C   
1358 O O   . GLU A 87  ? 0.35931 0.33419 0.45400 0.13163  -0.11552 0.03507  110 GLU A O   
1359 C CB  . GLU A 87  ? 0.36818 0.28972 0.35912 0.08024  -0.11095 0.05206  110 GLU A CB  
1360 C CG  . GLU A 87  ? 0.46931 0.43743 0.47773 0.08632  -0.13898 0.04107  110 GLU A CG  
1361 C CD  . GLU A 87  ? 0.52436 0.45746 0.46341 0.08911  -0.15403 0.05297  110 GLU A CD  
1362 O OE1 . GLU A 87  ? 0.61353 0.48724 0.49576 0.07929  -0.13586 0.06787  110 GLU A OE1 
1363 O OE2 . GLU A 87  ? 0.66957 0.63748 0.61107 0.09675  -0.17974 0.04337  110 GLU A OE2 
1370 N N   . LYS A 88  ? 0.32041 0.37361 0.47857 0.08680  -0.10814 0.00567  111 LYS A N   
1371 C CA  . LYS A 88  ? 0.34062 0.45857 0.56880 0.10452  -0.11895 -0.01659 111 LYS A CA  
1372 C C   . LYS A 88  ? 0.28127 0.40407 0.55190 0.10078  -0.08787 -0.02676 111 LYS A C   
1373 O O   . LYS A 88  ? 0.24110 0.42015 0.57655 0.11756  -0.09133 -0.04789 111 LYS A O   
1374 C CB  . LYS A 88  ? 0.29696 0.47949 0.56967 0.08163  -0.12618 -0.04456 111 LYS A CB  
1375 C CG  . LYS A 88  ? 0.42900 0.61436 0.66280 0.08056  -0.15546 -0.04177 111 LYS A CG  
1376 C CD  . LYS A 88  ? 0.51237 0.75818 0.79362 0.04833  -0.15294 -0.07683 111 LYS A CD  
1377 C CE  . LYS A 88  ? 0.64221 0.87478 0.87491 0.03374  -0.16848 -0.07614 111 LYS A CE  
1378 N NZ  . LYS A 88  ? 0.67894 0.95418 0.95173 -0.00628 -0.15436 -0.11327 111 LYS A NZ  
1392 N N   . HIS A 89  ? 0.30514 0.37707 0.54218 0.07992  -0.05799 -0.01581 112 HIS A N   
1393 C CA  . HIS A 89  ? 0.36777 0.43561 0.63033 0.07273  -0.02582 -0.02564 112 HIS A CA  
1394 C C   . HIS A 89  ? 0.32567 0.33393 0.54289 0.08196  -0.01402 -0.00876 112 HIS A C   
1395 O O   . HIS A 89  ? 0.30730 0.29647 0.52111 0.06947  0.01437  -0.01360 112 HIS A O   
1396 C CB  . HIS A 89  ? 0.23636 0.29645 0.49304 0.03767  0.00289  -0.03354 112 HIS A CB  
1397 C CG  . HIS A 89  ? 0.28283 0.38961 0.58194 0.01913  0.00436  -0.05632 112 HIS A CG  
1398 N ND1 . HIS A 89  ? 0.31143 0.46019 0.67235 0.00558  0.02833  -0.08579 112 HIS A ND1 
1399 C CD2 . HIS A 89  ? 0.22780 0.34583 0.51692 0.00726  -0.01094 -0.05887 112 HIS A CD2 
1400 C CE1 . HIS A 89  ? 0.28762 0.47268 0.67604 -0.01730 0.02837  -0.10755 112 HIS A CE1 
1401 N NE2 . HIS A 89  ? 0.33953 0.50424 0.68279 -0.01550 0.00368  -0.09088 112 HIS A NE2 
1409 N N   . VAL A 90  ? 0.38473 0.35672 0.55915 0.10038  -0.03191 0.00898  113 VAL A N   
1410 C CA  . VAL A 90  ? 0.38843 0.29764 0.51737 0.10298  -0.01518 0.01970  113 VAL A CA  
1411 C C   . VAL A 90  ? 0.37221 0.28134 0.53553 0.12248  0.00208  0.00874  113 VAL A C   
1412 O O   . VAL A 90  ? 0.35740 0.30106 0.56539 0.15583  -0.01191 0.00167  113 VAL A O   
1413 C CB  . VAL A 90  ? 0.43232 0.29110 0.50425 0.11922  -0.03076 0.03870  113 VAL A CB  
1414 C CG1 . VAL A 90  ? 0.64935 0.43327 0.67446 0.12132  -0.00649 0.04491  113 VAL A CG1 
1415 C CG2 . VAL A 90  ? 0.46108 0.31735 0.49769 0.09356  -0.03842 0.04572  113 VAL A CG2 
1425 N N   . ASN A 91  ? 0.38490 0.26003 0.52800 0.10390  0.03179  0.00432  114 ASN A N   
1426 C CA  . ASN A 91  ? 0.38505 0.24778 0.55063 0.11719  0.05687  -0.00801 114 ASN A CA  
1427 C C   . ASN A 91  ? 0.36224 0.28325 0.59155 0.10948  0.07161  -0.02917 114 ASN A C   
1428 O O   . ASN A 91  ? 0.39874 0.32241 0.65965 0.12091  0.09510  -0.04424 114 ASN A O   
1429 C CB  . ASN A 91  ? 0.47216 0.31086 0.64129 0.16355  0.04723  -0.00194 114 ASN A CB  
1430 C CG  . ASN A 91  ? 0.53361 0.28839 0.61862 0.16065  0.04866  0.01530  114 ASN A CG  
1431 O OD1 . ASN A 91  ? 0.62550 0.34202 0.66764 0.12498  0.06948  0.01437  114 ASN A OD1 
1432 N ND2 . ASN A 91  ? 0.65479 0.38893 0.71972 0.19199  0.02628  0.02720  114 ASN A ND2 
1439 N N   . GLY A 92  ? 0.29161 0.25205 0.53674 0.08811  0.06466  -0.03286 115 GLY A N   
1440 C CA  . GLY A 92  ? 0.39097 0.38163 0.67180 0.06650  0.09145  -0.05260 115 GLY A CA  
1441 C C   . GLY A 92  ? 0.28353 0.24031 0.50632 0.03579  0.10408  -0.04403 115 GLY A C   
1442 O O   . GLY A 92  ? 0.32698 0.24887 0.49304 0.03243  0.09305  -0.02786 115 GLY A O   
1446 N N   . THR A 93  ? 0.29974 0.26478 0.41479 0.02346  0.06548  -0.04472 116 THR A N   
1447 C CA  . THR A 93  ? 0.29613 0.26360 0.39028 0.01930  0.06871  -0.04259 116 THR A CA  
1448 C C   . THR A 93  ? 0.28740 0.26180 0.38859 0.01887  0.06298  -0.03742 116 THR A C   
1449 O O   . THR A 93  ? 0.30528 0.28387 0.42987 0.02164  0.05954  -0.03705 116 THR A O   
1450 C CB  . THR A 93  ? 0.33299 0.30064 0.42111 0.01820  0.08369  -0.04688 116 THR A CB  
1451 O OG1 . THR A 93  ? 0.28728 0.26047 0.39879 0.02010  0.09128  -0.04763 116 THR A OG1 
1452 C CG2 . THR A 93  ? 0.31887 0.27921 0.40039 0.01891  0.08930  -0.05349 116 THR A CG2 
1460 N N   . MET A 94  ? 0.24852 0.22394 0.33004 0.01552  0.06093  -0.03388 117 MET A N   
1461 C CA  . MET A 94  ? 0.23841 0.21992 0.32368 0.01439  0.05839  -0.02974 117 MET A CA  
1462 C C   . MET A 94  ? 0.26702 0.24936 0.33673 0.01151  0.06819  -0.02900 117 MET A C   
1463 O O   . MET A 94  ? 0.27626 0.25432 0.32542 0.01002  0.07158  -0.03057 117 MET A O   
1464 C CB  . MET A 94  ? 0.31631 0.29738 0.39242 0.01371  0.04548  -0.02541 117 MET A CB  
1465 C CG  . MET A 94  ? 0.31284 0.29123 0.40004 0.01716  0.03481  -0.02492 117 MET A CG  
1466 S SD  . MET A 94  ? 0.29942 0.27440 0.36746 0.01599  0.02284  -0.01990 117 MET A SD  
1467 C CE  . MET A 94  ? 0.32188 0.30425 0.39272 0.01450  0.02066  -0.01748 117 MET A CE  
1477 N N   . SER A 95  ? 0.24748 0.23472 0.32742 0.01095  0.07259  -0.02675 118 SER A N   
1478 C CA  . SER A 95  ? 0.30985 0.29656 0.37335 0.00863  0.08111  -0.02442 118 SER A CA  
1479 C C   . SER A 95  ? 0.25710 0.24348 0.30068 0.00650  0.07246  -0.02033 118 SER A C   
1480 O O   . SER A 95  ? 0.24008 0.22799 0.28641 0.00651  0.06120  -0.01862 118 SER A O   
1481 C CB  . SER A 95  ? 0.26958 0.26071 0.35177 0.00844  0.08922  -0.02259 118 SER A CB  
1482 O OG  . SER A 95  ? 0.25504 0.25076 0.34832 0.00792  0.07932  -0.01952 118 SER A OG  
1488 N N   . LEU A 96  ? 0.25008 0.23413 0.27317 0.00501  0.07806  -0.01865 119 LEU A N   
1489 C CA  . LEU A 96  ? 0.21318 0.19776 0.22058 0.00329  0.07057  -0.01470 119 LEU A CA  
1490 C C   . LEU A 96  ? 0.20353 0.19265 0.22381 0.00278  0.06653  -0.01045 119 LEU A C   
1491 O O   . LEU A 96  ? 0.26523 0.25557 0.27996 0.00195  0.05726  -0.00831 119 LEU A O   
1492 C CB  . LEU A 96  ? 0.28262 0.26356 0.26648 0.00260  0.07667  -0.01363 119 LEU A CB  
1493 C CG  . LEU A 96  ? 0.33684 0.31357 0.30302 0.00248  0.07457  -0.01828 119 LEU A CG  
1494 C CD1 . LEU A 96  ? 0.38358 0.35590 0.32663 0.00276  0.08108  -0.01829 119 LEU A CD1 
1495 C CD2 . LEU A 96  ? 0.30273 0.28078 0.26375 0.00104  0.06223  -0.01795 119 LEU A CD2 
1507 N N   . ALA A 97  ? 0.21976 0.21127 0.25834 0.00316  0.07368  -0.00971 120 ALA A N   
1508 C CA  . ALA A 97  ? 0.26584 0.26175 0.32102 0.00268  0.06867  -0.00726 120 ALA A CA  
1509 C C   . ALA A 97  ? 0.22681 0.22499 0.29318 0.00395  0.05588  -0.00944 120 ALA A C   
1510 O O   . ALA A 97  ? 0.22359 0.22300 0.28768 0.00350  0.04670  -0.00769 120 ALA A O   
1511 C CB  . ALA A 97  ? 0.24324 0.24155 0.32106 0.00269  0.07893  -0.00724 120 ALA A CB  
1517 N N   . GLU A 98  ? 0.20880 0.20673 0.28670 0.00599  0.05531  -0.01324 121 GLU A N   
1518 C CA  . GLU A 98  ? 0.23596 0.23419 0.32168 0.00802  0.04287  -0.01465 121 GLU A CA  
1519 C C   . GLU A 98  ? 0.25018 0.24458 0.31357 0.00732  0.03490  -0.01295 121 GLU A C   
1520 O O   . GLU A 98  ? 0.23854 0.23291 0.30156 0.00805  0.02473  -0.01181 121 GLU A O   
1521 C CB  . GLU A 98  ? 0.22698 0.22431 0.32717 0.01079  0.04415  -0.01854 121 GLU A CB  
1522 C CG  . GLU A 98  ? 0.24579 0.24792 0.37365 0.01183  0.05099  -0.02085 121 GLU A CG  
1523 C CD  . GLU A 98  ? 0.30230 0.30354 0.44421 0.01455  0.05509  -0.02499 121 GLU A CD  
1524 O OE1 . GLU A 98  ? 0.28235 0.27827 0.40925 0.01498  0.05669  -0.02622 121 GLU A OE1 
1525 O OE2 . GLU A 98  ? 0.43632 0.44233 0.60645 0.01626  0.05700  -0.02750 121 GLU A OE2 
1532 N N   . LEU A 99  ? 0.22513 0.21594 0.27006 0.00598  0.03939  -0.01322 122 LEU A N   
1533 C CA  . LEU A 99  ? 0.19968 0.18741 0.22654 0.00485  0.03274  -0.01193 122 LEU A CA  
1534 C C   . LEU A 99  ? 0.21847 0.20853 0.23721 0.00319  0.02916  -0.00852 122 LEU A C   
1535 O O   . LEU A 99  ? 0.23137 0.22028 0.24402 0.00308  0.02153  -0.00720 122 LEU A O   
1536 C CB  . LEU A 99  ? 0.27166 0.25581 0.28328 0.00355  0.03781  -0.01402 122 LEU A CB  
1537 C CG  . LEU A 99  ? 0.24513 0.22586 0.26481 0.00536  0.04030  -0.01791 122 LEU A CG  
1538 C CD1 . LEU A 99  ? 0.22544 0.20332 0.23436 0.00448  0.04846  -0.02154 122 LEU A CD1 
1539 C CD2 . LEU A 99  ? 0.26387 0.24034 0.28160 0.00601  0.03221  -0.01758 122 LEU A CD2 
1551 N N   . SER A 100 ? 0.21544 0.20792 0.23363 0.00208  0.03524  -0.00685 123 SER A N   
1552 C CA  . SER A 100 ? 0.21871 0.21306 0.23152 0.00088  0.03215  -0.00363 123 SER A CA  
1553 C C   . SER A 100 ? 0.22986 0.22615 0.25552 0.00189  0.02443  -0.00361 123 SER A C   
1554 O O   . SER A 100 ? 0.21860 0.21436 0.23677 0.00164  0.01764  -0.00260 123 SER A O   
1555 C CB  . SER A 100 ? 0.20350 0.19876 0.21577 0.00007  0.04077  -0.00118 123 SER A CB  
1556 O OG  . SER A 100 ? 0.21268 0.20511 0.20786 -0.00039 0.04639  -0.00115 123 SER A OG  
1562 N N   . ALA A 101 ? 0.18118 0.17961 0.22677 0.00321  0.02529  -0.00531 124 ALA A N   
1563 C CA  . ALA A 101 ? 0.17348 0.17366 0.23218 0.00462  0.01638  -0.00649 124 ALA A CA  
1564 C C   . ALA A 101 ? 0.21916 0.21571 0.26977 0.00657  0.00658  -0.00729 124 ALA A C   
1565 O O   . ALA A 101 ? 0.25057 0.24631 0.29811 0.00733  -0.00156 -0.00720 124 ALA A O   
1566 C CB  . ALA A 101 ? 0.20917 0.21290 0.29374 0.00583  0.01874  -0.00905 124 ALA A CB  
1572 N N   . ALA A 102 ? 0.19097 0.18428 0.23726 0.00754  0.00770  -0.00802 125 ALA A N   
1573 C CA  . ALA A 102 ? 0.18138 0.16954 0.21947 0.00953  -0.00043 -0.00775 125 ALA A CA  
1574 C C   . ALA A 102 ? 0.24128 0.22664 0.25916 0.00764  -0.00201 -0.00536 125 ALA A C   
1575 O O   . ALA A 102 ? 0.21314 0.19485 0.22357 0.00901  -0.00919 -0.00439 125 ALA A O   
1576 C CB  . ALA A 102 ? 0.20500 0.18954 0.24409 0.01071  0.00244  -0.00891 125 ALA A CB  
1582 N N   . ALA A 103 ? 0.22892 0.21570 0.23766 0.00476  0.00469  -0.00455 126 ALA A N   
1583 C CA  . ALA A 103 ? 0.24341 0.22886 0.23651 0.00287  0.00357  -0.00277 126 ALA A CA  
1584 C C   . ALA A 103 ? 0.22092 0.20843 0.21402 0.00295  -0.00043 -0.00180 126 ALA A C   
1585 O O   . ALA A 103 ? 0.20353 0.18833 0.18693 0.00301  -0.00427 -0.00093 126 ALA A O   
1586 C CB  . ALA A 103 ? 0.20484 0.19208 0.19033 0.00033  0.01018  -0.00276 126 ALA A CB  
1592 N N   . LEU A 104 ? 0.24667 0.23834 0.25085 0.00287  0.00128  -0.00211 127 LEU A N   
1593 C CA  . LEU A 104 ? 0.19421 0.18767 0.19953 0.00261  -0.00160 -0.00168 127 LEU A CA  
1594 C C   . LEU A 104 ? 0.18343 0.17529 0.19474 0.00505  -0.01017 -0.00380 127 LEU A C   
1595 O O   . LEU A 104 ? 0.24075 0.23150 0.24615 0.00529  -0.01427 -0.00413 127 LEU A O   
1596 C CB  . LEU A 104 ? 0.18377 0.18117 0.19964 0.00146  0.00417  -0.00087 127 LEU A CB  
1597 C CG  . LEU A 104 ? 0.17630 0.17432 0.18190 -0.00036 0.01111  0.00175  127 LEU A CG  
1598 C CD1 . LEU A 104 ? 0.26956 0.26939 0.28359 -0.00102 0.01762  0.00373  127 LEU A CD1 
1599 C CD2 . LEU A 104 ? 0.21059 0.20819 0.20353 -0.00110 0.00808  0.00294  127 LEU A CD2 
1611 N N   . GLN A 105 ? 0.21089 0.20255 0.23410 0.00718  -0.01319 -0.00567 128 GLN A N   
1612 C CA  . GLN A 105 ? 0.22229 0.21329 0.25453 0.00998  -0.02264 -0.00848 128 GLN A CA  
1613 C C   . GLN A 105 ? 0.26691 0.25138 0.28869 0.01325  -0.03041 -0.00842 128 GLN A C   
1614 O O   . GLN A 105 ? 0.24359 0.22531 0.26372 0.01599  -0.03980 -0.01037 128 GLN A O   
1615 C CB  . GLN A 105 ? 0.23663 0.23251 0.29372 0.01064  -0.02193 -0.01104 128 GLN A CB  
1616 C CG  . GLN A 105 ? 0.22633 0.22719 0.29463 0.00762  -0.01363 -0.01048 128 GLN A CG  
1617 C CD  . GLN A 105 ? 0.26356 0.26903 0.35874 0.00799  -0.01187 -0.01314 128 GLN A CD  
1618 O OE1 . GLN A 105 ? 0.25628 0.26229 0.36148 0.00995  -0.01276 -0.01474 128 GLN A OE1 
1619 N NE2 . GLN A 105 ? 0.24468 0.25339 0.35370 0.00610  -0.00889 -0.01370 128 GLN A NE2 
1628 N N   . TYR A 106 ? 0.27139 0.25243 0.28555 0.01326  -0.02691 -0.00632 129 TYR A N   
1629 C CA  . TYR A 106 ? 0.25359 0.22655 0.25542 0.01618  -0.03265 -0.00484 129 TYR A CA  
1630 C C   . TYR A 106 ? 0.27724 0.24553 0.26001 0.01387  -0.02724 -0.00165 129 TYR A C   
1631 O O   . TYR A 106 ? 0.32216 0.28243 0.29314 0.01576  -0.02993 0.00054  129 TYR A O   
1632 C CB  . TYR A 106 ? 0.20308 0.17487 0.21726 0.01892  -0.03437 -0.00552 129 TYR A CB  
1633 C CG  . TYR A 106 ? 0.28767 0.26384 0.32302 0.02185  -0.04154 -0.00914 129 TYR A CG  
1634 C CD1 . TYR A 106 ? 0.27041 0.25501 0.32686 0.01988  -0.03584 -0.01166 129 TYR A CD1 
1635 C CD2 . TYR A 106 ? 0.36594 0.33754 0.40032 0.02661  -0.05388 -0.01014 129 TYR A CD2 
1636 C CE1 . TYR A 106 ? 0.33987 0.32922 0.41962 0.02209  -0.04182 -0.01550 129 TYR A CE1 
1637 C CE2 . TYR A 106 ? 0.32525 0.30176 0.38216 0.02939  -0.06197 -0.01450 129 TYR A CE2 
1638 C CZ  . TYR A 106 ? 0.33868 0.32460 0.41978 0.02678  -0.05558 -0.01736 129 TYR A CZ  
1639 O OH  . TYR A 106 ? 0.45023 0.44174 0.55728 0.02899  -0.06283 -0.02215 129 TYR A OH  
1649 N N   . SER A 107 ? 0.24711 0.21983 0.22741 0.01000  -0.01976 -0.00122 130 SER A N   
1650 C CA  . SER A 107 ? 0.27962 0.24946 0.24563 0.00745  -0.01491 0.00090  130 SER A CA  
1651 C C   . SER A 107 ? 0.25160 0.21658 0.21577 0.00746  -0.01239 0.00184  130 SER A C   
1652 O O   . SER A 107 ? 0.23951 0.19845 0.19244 0.00672  -0.01101 0.00389  130 SER A O   
1653 C CB  . SER A 107 ? 0.28301 0.24773 0.23473 0.00823  -0.01799 0.00226  130 SER A CB  
1654 O OG  . SER A 107 ? 0.29568 0.26180 0.23988 0.00489  -0.01208 0.00326  130 SER A OG  
1660 N N   . ASP A 108 ? 0.21160 0.17879 0.18814 0.00826  -0.01102 0.00013  131 ASP A N   
1661 C CA  . ASP A 108 ? 0.21135 0.17372 0.18847 0.00860  -0.00864 0.00018  131 ASP A CA  
1662 C C   . ASP A 108 ? 0.24174 0.20474 0.21188 0.00455  -0.00182 -0.00026 131 ASP A C   
1663 O O   . ASP A 108 ? 0.25660 0.22593 0.22836 0.00225  0.00225  -0.00189 131 ASP A O   
1664 C CB  . ASP A 108 ? 0.24796 0.21352 0.24197 0.01056  -0.00792 -0.00244 131 ASP A CB  
1665 C CG  . ASP A 108 ? 0.27251 0.23241 0.26953 0.01184  -0.00621 -0.00298 131 ASP A CG  
1666 O OD1 . ASP A 108 ? 0.21111 0.16982 0.20319 0.00903  -0.00009 -0.00404 131 ASP A OD1 
1667 O OD2 . ASP A 108 ? 0.27471 0.23111 0.27992 0.01591  -0.01155 -0.00274 131 ASP A OD2 
1672 N N   . ASN A 109 ? 0.25296 0.20880 0.21538 0.00380  -0.00085 0.00123  132 ASN A N   
1673 C CA  . ASN A 109 ? 0.22589 0.18240 0.18346 -0.00029 0.00445  0.00007  132 ASN A CA  
1674 C C   . ASN A 109 ? 0.21156 0.16889 0.17528 -0.00131 0.00852  -0.00371 132 ASN A C   
1675 O O   . ASN A 109 ? 0.24347 0.20423 0.20467 -0.00444 0.01191  -0.00633 132 ASN A O   
1676 C CB  . ASN A 109 ? 0.27671 0.22491 0.22567 -0.00124 0.00508  0.00298  132 ASN A CB  
1677 C CG  . ASN A 109 ? 0.27512 0.22404 0.21540 -0.00205 0.00447  0.00534  132 ASN A CG  
1678 O OD1 . ASN A 109 ? 0.27056 0.22691 0.21189 -0.00258 0.00373  0.00423  132 ASN A OD1 
1679 N ND2 . ASN A 109 ? 0.29100 0.23140 0.22253 -0.00208 0.00567  0.00875  132 ASN A ND2 
1686 N N   . VAL A 110 ? 0.22475 0.17875 0.19647 0.00153  0.00796  -0.00458 133 VAL A N   
1687 C CA  . VAL A 110 ? 0.25791 0.21281 0.23557 0.00095  0.01273  -0.00904 133 VAL A CA  
1688 C C   . VAL A 110 ? 0.23640 0.19954 0.21597 0.00033  0.01580  -0.01119 133 VAL A C   
1689 O O   . VAL A 110 ? 0.23227 0.19744 0.20772 -0.00178 0.02014  -0.01452 133 VAL A O   
1690 C CB  . VAL A 110 ? 0.21185 0.16169 0.20009 0.00471  0.01181  -0.00961 133 VAL A CB  
1691 C CG1 . VAL A 110 ? 0.20938 0.16013 0.20365 0.00420  0.01817  -0.01520 133 VAL A CG1 
1692 C CG2 . VAL A 110 ? 0.28366 0.22347 0.26850 0.00577  0.00907  -0.00648 133 VAL A CG2 
1702 N N   . ALA A 111 ? 0.24044 0.20764 0.22565 0.00227  0.01339  -0.00928 134 ALA A N   
1703 C CA  . ALA A 111 ? 0.21927 0.19315 0.20697 0.00170  0.01701  -0.01008 134 ALA A CA  
1704 C C   . ALA A 111 ? 0.23277 0.20951 0.20841 -0.00133 0.01850  -0.00976 134 ALA A C   
1705 O O   . ALA A 111 ? 0.21968 0.19865 0.19162 -0.00224 0.02329  -0.01159 134 ALA A O   
1706 C CB  . ALA A 111 ? 0.25700 0.23423 0.25373 0.00370  0.01310  -0.00800 134 ALA A CB  
1712 N N   . MET A 112 ? 0.20932 0.18557 0.17833 -0.00258 0.01449  -0.00749 135 MET A N   
1713 C CA  . MET A 112 ? 0.22669 0.20610 0.18690 -0.00517 0.01503  -0.00751 135 MET A CA  
1714 C C   . MET A 112 ? 0.20823 0.18626 0.16353 -0.00707 0.01768  -0.01137 135 MET A C   
1715 O O   . MET A 112 ? 0.21636 0.19757 0.16575 -0.00796 0.01910  -0.01285 135 MET A O   
1716 C CB  . MET A 112 ? 0.23105 0.20951 0.18732 -0.00608 0.01142  -0.00505 135 MET A CB  
1717 C CG  . MET A 112 ? 0.21338 0.19542 0.16386 -0.00870 0.01158  -0.00558 135 MET A CG  
1718 S SD  . MET A 112 ? 0.22647 0.21512 0.17536 -0.00826 0.01201  -0.00470 135 MET A SD  
1719 C CE  . MET A 112 ? 0.24332 0.23516 0.18922 -0.01021 0.00955  -0.00405 135 MET A CE  
1729 N N   . ASN A 113 ? 0.20733 0.17992 0.16452 -0.00748 0.01791  -0.01320 136 ASN A N   
1730 C CA  . ASN A 113 ? 0.24351 0.21439 0.19731 -0.00952 0.01985  -0.01804 136 ASN A CA  
1731 C C   . ASN A 113 ? 0.22297 0.19470 0.17492 -0.00833 0.02396  -0.02169 136 ASN A C   
1732 O O   . ASN A 113 ? 0.23789 0.21026 0.18235 -0.00966 0.02469  -0.02575 136 ASN A O   
1733 C CB  . ASN A 113 ? 0.21089 0.17452 0.16892 -0.01009 0.02002  -0.01913 136 ASN A CB  
1734 C CG  . ASN A 113 ? 0.20265 0.16449 0.15920 -0.01269 0.01814  -0.01699 136 ASN A CG  
1735 O OD1 . ASN A 113 ? 0.23986 0.20687 0.19308 -0.01426 0.01669  -0.01607 136 ASN A OD1 
1736 N ND2 . ASN A 113 ? 0.22747 0.18153 0.18715 -0.01305 0.01891  -0.01612 136 ASN A ND2 
1743 N N   . LYS A 114 ? 0.21170 0.18316 0.17042 -0.00568 0.02676  -0.02067 137 LYS A N   
1744 C CA  . LYS A 114 ? 0.22778 0.19957 0.18462 -0.00451 0.03274  -0.02382 137 LYS A CA  
1745 C C   . LYS A 114 ? 0.24409 0.22020 0.19175 -0.00470 0.03403  -0.02185 137 LYS A C   
1746 O O   . LYS A 114 ? 0.25985 0.23497 0.19729 -0.00457 0.03781  -0.02485 137 LYS A O   
1747 C CB  . LYS A 114 ? 0.24115 0.21212 0.21139 -0.00171 0.03605  -0.02335 137 LYS A CB  
1748 C CG  . LYS A 114 ? 0.27571 0.24117 0.25501 -0.00056 0.03483  -0.02528 137 LYS A CG  
1749 C CD  . LYS A 114 ? 0.32578 0.28644 0.29960 -0.00182 0.03775  -0.03128 137 LYS A CD  
1750 C CE  . LYS A 114 ? 0.33338 0.28768 0.31795 -0.00015 0.03810  -0.03336 137 LYS A CE  
1751 N NZ  . LYS A 114 ? 0.30749 0.25699 0.28635 -0.00192 0.04081  -0.04007 137 LYS A NZ  
1765 N N   . LEU A 115 ? 0.23049 0.21042 0.18065 -0.00463 0.03106  -0.01686 138 LEU A N   
1766 C CA  . LEU A 115 ? 0.23390 0.21696 0.17575 -0.00463 0.03198  -0.01429 138 LEU A CA  
1767 C C   . LEU A 115 ? 0.23302 0.21644 0.16223 -0.00614 0.02844  -0.01644 138 LEU A C   
1768 O O   . LEU A 115 ? 0.25923 0.24216 0.17668 -0.00546 0.03032  -0.01728 138 LEU A O   
1769 C CB  . LEU A 115 ? 0.25157 0.23815 0.19979 -0.00444 0.02865  -0.00933 138 LEU A CB  
1770 C CG  . LEU A 115 ? 0.20892 0.19601 0.17157 -0.00291 0.02992  -0.00773 138 LEU A CG  
1771 C CD1 . LEU A 115 ? 0.24032 0.23029 0.20678 -0.00297 0.02528  -0.00412 138 LEU A CD1 
1772 C CD2 . LEU A 115 ? 0.23849 0.22549 0.20495 -0.00172 0.03795  -0.00782 138 LEU A CD2 
1784 N N   . ILE A 116 ? 0.26326 0.24719 0.19495 -0.00802 0.02319  -0.01733 139 ILE A N   
1785 C CA  . ILE A 116 ? 0.24839 0.23356 0.17270 -0.00978 0.01908  -0.02035 139 ILE A CA  
1786 C C   . ILE A 116 ? 0.26825 0.24997 0.18431 -0.00971 0.02097  -0.02654 139 ILE A C   
1787 O O   . ILE A 116 ? 0.26803 0.25054 0.17257 -0.00932 0.01883  -0.02866 139 ILE A O   
1788 C CB  . ILE A 116 ? 0.21369 0.19894 0.14524 -0.01221 0.01543  -0.02080 139 ILE A CB  
1789 C CG1 . ILE A 116 ? 0.21273 0.20127 0.14850 -0.01211 0.01331  -0.01555 139 ILE A CG1 
1790 C CG2 . ILE A 116 ? 0.23984 0.22624 0.16799 -0.01445 0.01174  -0.02593 139 ILE A CG2 
1791 C CD1 . ILE A 116 ? 0.25382 0.24058 0.19550 -0.01407 0.01203  -0.01508 139 ILE A CD1 
1803 N N   . ALA A 117 ? 0.26941 0.24666 0.19079 -0.00982 0.02429  -0.02997 140 ALA A N   
1804 C CA  . ALA A 117 ? 0.23546 0.20871 0.14918 -0.00980 0.02622  -0.03708 140 ALA A CA  
1805 C C   . ALA A 117 ? 0.24646 0.21871 0.14702 -0.00724 0.03095  -0.03714 140 ALA A C   
1806 O O   . ALA A 117 ? 0.28185 0.25204 0.16811 -0.00682 0.02985  -0.04202 140 ALA A O   
1807 C CB  . ALA A 117 ? 0.27239 0.24043 0.19594 -0.00979 0.02991  -0.04026 140 ALA A CB  
1813 N N   . HIS A 118 ? 0.26238 0.23537 0.16742 -0.00541 0.03642  -0.03198 141 HIS A N   
1814 C CA  . HIS A 118 ? 0.27170 0.24234 0.16583 -0.00308 0.04361  -0.03141 141 HIS A CA  
1815 C C   . HIS A 118 ? 0.32439 0.29581 0.20132 -0.00232 0.04015  -0.02923 141 HIS A C   
1816 O O   . HIS A 118 ? 0.39382 0.36085 0.25332 -0.00056 0.04332  -0.03181 141 HIS A O   
1817 C CB  . HIS A 118 ? 0.35966 0.33162 0.26573 -0.00177 0.05017  -0.02613 141 HIS A CB  
1818 C CG  . HIS A 118 ? 0.44132 0.41004 0.33716 0.00032  0.05966  -0.02512 141 HIS A CG  
1819 N ND1 . HIS A 118 ? 0.55576 0.51964 0.44865 0.00161  0.06823  -0.03018 141 HIS A ND1 
1820 C CD2 . HIS A 118 ? 0.63505 0.60347 0.52112 0.00146  0.06271  -0.01961 141 HIS A CD2 
1821 C CE1 . HIS A 118 ? 0.56018 0.52088 0.44153 0.00339  0.07700  -0.02764 141 HIS A CE1 
1822 N NE2 . HIS A 118 ? 0.57735 0.54039 0.45422 0.00333  0.07374  -0.02083 141 HIS A NE2 
1830 N N   . VAL A 119 ? 0.25899 0.23529 0.13943 -0.00323 0.03330  -0.02478 142 VAL A N   
1831 C CA  . VAL A 119 ? 0.31052 0.28741 0.17619 -0.00176 0.02966  -0.02185 142 VAL A CA  
1832 C C   . VAL A 119 ? 0.33100 0.30858 0.18755 -0.00244 0.02070  -0.02755 142 VAL A C   
1833 O O   . VAL A 119 ? 0.35791 0.33556 0.20094 -0.00058 0.01597  -0.02604 142 VAL A O   
1834 C CB  . VAL A 119 ? 0.39618 0.37770 0.27009 -0.00175 0.02709  -0.01438 142 VAL A CB  
1835 C CG1 . VAL A 119 ? 0.42001 0.40078 0.30321 -0.00100 0.03531  -0.00941 142 VAL A CG1 
1836 C CG2 . VAL A 119 ? 0.32211 0.30869 0.21008 -0.00426 0.02037  -0.01502 142 VAL A CG2 
1847 N N   . GLY A 120 ? 0.31257 0.29030 0.17691 -0.00490 0.01790  -0.03414 143 GLY A N   
1848 C CA  . GLY A 120 ? 0.33578 0.31416 0.19430 -0.00594 0.00961  -0.04100 143 GLY A CA  
1849 C C   . GLY A 120 ? 0.31216 0.29594 0.18735 -0.00937 0.00306  -0.04224 143 GLY A C   
1850 O O   . GLY A 120 ? 0.35856 0.34439 0.23307 -0.01059 -0.00453 -0.04779 143 GLY A O   
1854 N N   . GLY A 121 ? 0.24462 0.23037 0.13484 -0.01090 0.00592  -0.03757 144 GLY A N   
1855 C CA  . GLY A 121 ? 0.24674 0.23608 0.15119 -0.01409 0.00183  -0.03830 144 GLY A CA  
1856 C C   . GLY A 121 ? 0.23314 0.22849 0.14214 -0.01387 -0.00172 -0.03271 144 GLY A C   
1857 O O   . GLY A 121 ? 0.30197 0.29867 0.20324 -0.01117 -0.00198 -0.02811 144 GLY A O   
1861 N N   . PRO A 122 ? 0.25061 0.24893 0.17283 -0.01670 -0.00359 -0.03283 145 PRO A N   
1862 C CA  . PRO A 122 ? 0.22564 0.22921 0.15374 -0.01641 -0.00542 -0.02771 145 PRO A CA  
1863 C C   . PRO A 122 ? 0.23477 0.24318 0.15756 -0.01448 -0.01202 -0.02791 145 PRO A C   
1864 O O   . PRO A 122 ? 0.26288 0.27384 0.18539 -0.01247 -0.01232 -0.02238 145 PRO A O   
1865 C CB  . PRO A 122 ? 0.24648 0.25122 0.18873 -0.02005 -0.00506 -0.02927 145 PRO A CB  
1866 C CG  . PRO A 122 ? 0.21452 0.21251 0.15840 -0.02174 -0.00083 -0.03205 145 PRO A CG  
1867 C CD  . PRO A 122 ? 0.26671 0.26242 0.19931 -0.02014 -0.00228 -0.03693 145 PRO A CD  
1875 N N   . ALA A 123 ? 0.27105 0.28031 0.18954 -0.01467 -0.01793 -0.03427 146 ALA A N   
1876 C CA  . ALA A 123 ? 0.26764 0.28090 0.17985 -0.01195 -0.02581 -0.03427 146 ALA A CA  
1877 C C   . ALA A 123 ? 0.26108 0.27019 0.15492 -0.00756 -0.02401 -0.02910 146 ALA A C   
1878 O O   . ALA A 123 ? 0.25276 0.26394 0.14108 -0.00449 -0.02893 -0.02566 146 ALA A O   
1879 C CB  . ALA A 123 ? 0.29830 0.31297 0.20922 -0.01274 -0.03414 -0.04321 146 ALA A CB  
1885 N N   . SER A 124 ? 0.29884 0.30159 0.18345 -0.00705 -0.01678 -0.02863 147 SER A N   
1886 C CA  A SER A 124 ? 0.27477 0.27303 0.14409 -0.00335 -0.01257 -0.02304 147 SER A CA  
1887 C CA  B SER A 124 ? 0.27543 0.27368 0.14478 -0.00336 -0.01255 -0.02305 147 SER A CA  
1888 C C   . SER A 124 ? 0.24505 0.24481 0.12299 -0.00294 -0.00783 -0.01502 147 SER A C   
1889 O O   . SER A 124 ? 0.29370 0.29213 0.16400 0.00002  -0.00729 -0.00920 147 SER A O   
1890 C CB  A SER A 124 ? 0.29197 0.28331 0.15101 -0.00297 -0.00521 -0.02574 147 SER A CB  
1891 C CB  B SER A 124 ? 0.29280 0.28419 0.15210 -0.00304 -0.00525 -0.02586 147 SER A CB  
1892 O OG  A SER A 124 ? 0.31106 0.29775 0.15726 0.00025  0.00099  -0.01979 147 SER A OG  
1893 O OG  B SER A 124 ? 0.29066 0.27984 0.14002 -0.00305 -0.01011 -0.03409 147 SER A OG  
1904 N N   . VAL A 125 ? 0.23277 0.23438 0.12588 -0.00566 -0.00455 -0.01464 148 VAL A N   
1905 C CA  . VAL A 125 ? 0.22792 0.23110 0.12915 -0.00515 -0.00172 -0.00826 148 VAL A CA  
1906 C C   . VAL A 125 ? 0.28954 0.29760 0.19418 -0.00409 -0.00784 -0.00597 148 VAL A C   
1907 O O   . VAL A 125 ? 0.24079 0.24869 0.14462 -0.00189 -0.00700 -0.00036 148 VAL A O   
1908 C CB  . VAL A 125 ? 0.24465 0.24807 0.15895 -0.00765 0.00154  -0.00858 148 VAL A CB  
1909 C CG1 . VAL A 125 ? 0.20373 0.20838 0.12482 -0.00674 0.00331  -0.00307 148 VAL A CG1 
1910 C CG2 . VAL A 125 ? 0.27076 0.26943 0.18372 -0.00807 0.00687  -0.01074 148 VAL A CG2 
1920 N N   . THR A 126 ? 0.25128 0.26371 0.16154 -0.00559 -0.01401 -0.01060 149 THR A N   
1921 C CA  . THR A 126 ? 0.21733 0.23523 0.13357 -0.00436 -0.02023 -0.00933 149 THR A CA  
1922 C C   . THR A 126 ? 0.25072 0.26699 0.15308 -0.00009 -0.02499 -0.00653 149 THR A C   
1923 O O   . THR A 126 ? 0.22592 0.24399 0.13084 0.00237  -0.02733 -0.00183 149 THR A O   
1924 C CB  . THR A 126 ? 0.26369 0.28694 0.19148 -0.00713 -0.02536 -0.01573 149 THR A CB  
1925 O OG1 . THR A 126 ? 0.23873 0.26171 0.17773 -0.01075 -0.01961 -0.01668 149 THR A OG1 
1926 C CG2 . THR A 126 ? 0.21572 0.24570 0.15288 -0.00560 -0.03211 -0.01520 149 THR A CG2 
1934 N N   . ALA A 127 ? 0.24690 0.25892 0.13358 0.00117  -0.02655 -0.00940 150 ALA A N   
1935 C CA  . ALA A 127 ? 0.28143 0.28982 0.15054 0.00584  -0.03084 -0.00618 150 ALA A CA  
1936 C C   . ALA A 127 ? 0.28600 0.28902 0.14864 0.00815  -0.02319 0.00255  150 ALA A C   
1937 O O   . ALA A 127 ? 0.28824 0.28923 0.14335 0.01200  -0.02619 0.00818  150 ALA A O   
1938 C CB  . ALA A 127 ? 0.31285 0.31624 0.16366 0.00679  -0.03292 -0.01172 150 ALA A CB  
1944 N N   . PHE A 128 ? 0.25042 0.25114 0.11803 0.00589  -0.01365 0.00381  151 PHE A N   
1945 C CA  . PHE A 128 ? 0.29555 0.29200 0.16206 0.00732  -0.00599 0.01125  151 PHE A CA  
1946 C C   . PHE A 128 ? 0.27719 0.27747 0.15712 0.00783  -0.00823 0.01570  151 PHE A C   
1947 O O   . PHE A 128 ? 0.29347 0.29027 0.16890 0.01075  -0.00712 0.02226  151 PHE A O   
1948 C CB  . PHE A 128 ? 0.26532 0.25995 0.13843 0.00468  0.00306  0.01011  151 PHE A CB  
1949 C CG  . PHE A 128 ? 0.23931 0.23146 0.11881 0.00516  0.01043  0.01645  151 PHE A CG  
1950 C CD1 . PHE A 128 ? 0.30994 0.29558 0.17743 0.00783  0.01599  0.02213  151 PHE A CD1 
1951 C CD2 . PHE A 128 ? 0.33020 0.32576 0.22715 0.00305  0.01184  0.01656  151 PHE A CD2 
1952 C CE1 . PHE A 128 ? 0.34332 0.32666 0.21965 0.00779  0.02320  0.02757  151 PHE A CE1 
1953 C CE2 . PHE A 128 ? 0.29738 0.29093 0.20200 0.00336  0.01750  0.02124  151 PHE A CE2 
1954 C CZ  . PHE A 128 ? 0.25345 0.24113 0.14897 0.00549  0.02344  0.02661  151 PHE A CZ  
1964 N N   . ALA A 129 ? 0.25113 0.25764 0.14733 0.00509  -0.01053 0.01228  152 ALA A N   
1965 C CA  . ALA A 129 ? 0.26974 0.28010 0.17822 0.00580  -0.01312 0.01502  152 ALA A CA  
1966 C C   . ALA A 129 ? 0.25162 0.26259 0.15451 0.00970  -0.02050 0.01773  152 ALA A C   
1967 O O   . ALA A 129 ? 0.25016 0.25935 0.15510 0.01228  -0.02015 0.02350  152 ALA A O   
1968 C CB  . ALA A 129 ? 0.23726 0.25369 0.16046 0.00256  -0.01473 0.00991  152 ALA A CB  
1974 N N   . ARG A 130 ? 0.23362 0.24681 0.13010 0.01046  -0.02802 0.01336  153 ARG A N   
1975 C CA  . ARG A 130 ? 0.24555 0.25968 0.13738 0.01481  -0.03715 0.01544  153 ARG A CA  
1976 C C   . ARG A 130 ? 0.27030 0.27537 0.14384 0.01919  -0.03476 0.02342  153 ARG A C   
1977 O O   . ARG A 130 ? 0.32690 0.33061 0.20097 0.02302  -0.03818 0.02923  153 ARG A O   
1978 C CB  . ARG A 130 ? 0.25464 0.27204 0.14163 0.01489  -0.04633 0.00832  153 ARG A CB  
1979 C CG  . ARG A 130 ? 0.27111 0.29720 0.17811 0.01050  -0.04859 0.00069  153 ARG A CG  
1980 C CD  . ARG A 130 ? 0.29076 0.32423 0.21712 0.01133  -0.05293 0.00133  153 ARG A CD  
1981 N NE  . ARG A 130 ? 0.28440 0.32514 0.22970 0.00676  -0.05261 -0.00554 153 ARG A NE  
1982 C CZ  . ARG A 130 ? 0.27943 0.32015 0.23351 0.00273  -0.04367 -0.00603 153 ARG A CZ  
1983 N NH1 . ARG A 130 ? 0.25048 0.28621 0.20018 0.00288  -0.03587 -0.00073 153 ARG A NH1 
1984 N NH2 . ARG A 130 ? 0.27979 0.32503 0.24741 -0.00145 -0.04269 -0.01199 153 ARG A NH2 
1998 N N   . GLN A 131 ? 0.27563 0.27375 0.13354 0.01872  -0.02783 0.02407  154 GLN A N   
1999 C CA  . GLN A 131 ? 0.34068 0.32876 0.18010 0.02250  -0.02288 0.03203  154 GLN A CA  
2000 C C   . GLN A 131 ? 0.31845 0.30432 0.16881 0.02293  -0.01662 0.03965  154 GLN A C   
2001 O O   . GLN A 131 ? 0.34214 0.32067 0.18170 0.02698  -0.01564 0.04755  154 GLN A O   
2002 C CB  . GLN A 131 ? 0.38130 0.36313 0.20637 0.02110  -0.01396 0.03037  154 GLN A CB  
2003 C CG  . GLN A 131 ? 0.54445 0.51474 0.34623 0.02510  -0.00792 0.03770  154 GLN A CG  
2004 C CD  . GLN A 131 ? 0.67250 0.63698 0.46136 0.02373  0.00203  0.03501  154 GLN A CD  
2005 O OE1 . GLN A 131 ? 0.64308 0.61224 0.44183 0.01979  0.00412  0.02771  154 GLN A OE1 
2006 N NE2 . GLN A 131 ? 0.78443 0.73783 0.55078 0.02727  0.00881  0.04122  154 GLN A NE2 
2015 N N   . LEU A 132 ? 0.30700 0.29825 0.17798 0.01902  -0.01265 0.03736  155 LEU A N   
2016 C CA  . LEU A 132 ? 0.32422 0.31404 0.20822 0.01894  -0.00758 0.04264  155 LEU A CA  
2017 C C   . LEU A 132 ? 0.39077 0.38470 0.28632 0.02115  -0.01484 0.04402  155 LEU A C   
2018 O O   . LEU A 132 ? 0.35967 0.35249 0.26731 0.02120  -0.01142 0.04746  155 LEU A O   
2019 C CB  . LEU A 132 ? 0.30816 0.30162 0.20812 0.01433  -0.00167 0.03859  155 LEU A CB  
2020 C CG  . LEU A 132 ? 0.38650 0.37715 0.28244 0.01182  0.00620  0.03666  155 LEU A CG  
2021 C CD1 . LEU A 132 ? 0.35071 0.34513 0.26438 0.00834  0.00929  0.03326  155 LEU A CD1 
2022 C CD2 . LEU A 132 ? 0.46640 0.44818 0.35142 0.01381  0.01425  0.04350  155 LEU A CD2 
2034 N N   . GLY A 133 ? 0.30283 0.30219 0.19796 0.02268  -0.02471 0.04034  156 GLY A N   
2035 C CA  . GLY A 133 ? 0.28924 0.29380 0.19888 0.02465  -0.03120 0.04052  156 GLY A CA  
2036 C C   . GLY A 133 ? 0.24761 0.26106 0.17737 0.02081  -0.03111 0.03374  156 GLY A C   
2037 O O   . GLY A 133 ? 0.32898 0.34642 0.27314 0.02219  -0.03403 0.03376  156 GLY A O   
2041 N N   . ASP A 134 ? 0.24265 0.25860 0.17350 0.01634  -0.02746 0.02811  157 ASP A N   
2042 C CA  . ASP A 134 ? 0.22392 0.24670 0.17069 0.01283  -0.02664 0.02217  157 ASP A CA  
2043 C C   . ASP A 134 ? 0.27255 0.30155 0.22130 0.01192  -0.03346 0.01620  157 ASP A C   
2044 O O   . ASP A 134 ? 0.22397 0.25196 0.16374 0.01004  -0.03355 0.01295  157 ASP A O   
2045 C CB  . ASP A 134 ? 0.19323 0.21360 0.14020 0.00900  -0.01874 0.02051  157 ASP A CB  
2046 C CG  . ASP A 134 ? 0.19735 0.22229 0.15720 0.00589  -0.01686 0.01559  157 ASP A CG  
2047 O OD1 . ASP A 134 ? 0.18431 0.21508 0.15227 0.00530  -0.02054 0.01183  157 ASP A OD1 
2048 O OD2 . ASP A 134 ? 0.19890 0.22116 0.16043 0.00412  -0.01155 0.01545  157 ASP A OD2 
2053 N N   . GLU A 135 ? 0.25026 0.28574 0.21251 0.01331  -0.03915 0.01430  158 GLU A N   
2054 C CA  . GLU A 135 ? 0.21519 0.25761 0.18400 0.01242  -0.04630 0.00810  158 GLU A CA  
2055 C C   . GLU A 135 ? 0.28893 0.33717 0.27495 0.00785  -0.04176 0.00250  158 GLU A C   
2056 O O   . GLU A 135 ? 0.23587 0.29080 0.23332 0.00648  -0.04628 -0.00297 158 GLU A O   
2057 C CB  . GLU A 135 ? 0.28726 0.33313 0.26036 0.01757  -0.05674 0.00958  158 GLU A CB  
2058 C CG  . GLU A 135 ? 0.33953 0.37679 0.28934 0.02235  -0.06061 0.01601  158 GLU A CG  
2059 C CD  . GLU A 135 ? 0.57077 0.60918 0.51667 0.02827  -0.07358 0.01735  158 GLU A CD  
2060 O OE1 . GLU A 135 ? 0.35630 0.40328 0.32112 0.02935  -0.08072 0.01364  158 GLU A OE1 
2061 O OE2 . GLU A 135 ? 0.40904 0.43914 0.33227 0.03227  -0.07661 0.02237  158 GLU A OE2 
2068 N N   . THR A 136 ? 0.18138 0.22636 0.16830 0.00538  -0.03273 0.00361  159 THR A N   
2069 C CA  . THR A 136 ? 0.19088 0.23893 0.19028 0.00162  -0.02700 -0.00042 159 THR A CA  
2070 C C   . THR A 136 ? 0.23112 0.27513 0.22292 -0.00234 -0.02174 -0.00240 159 THR A C   
2071 O O   . THR A 136 ? 0.20448 0.25105 0.20366 -0.00566 -0.02001 -0.00672 159 THR A O   
2072 C CB  . THR A 136 ? 0.24990 0.29650 0.25557 0.00261  -0.02154 0.00188  159 THR A CB  
2073 O OG1 . THR A 136 ? 0.23168 0.28121 0.24514 0.00673  -0.02634 0.00404  159 THR A OG1 
2074 C CG2 . THR A 136 ? 0.23645 0.28544 0.25323 -0.00067 -0.01505 -0.00225 159 THR A CG2 
2082 N N   . PHE A 137 ? 0.18978 0.22725 0.16855 -0.00193 -0.01877 0.00089  160 PHE A N   
2083 C CA  . PHE A 137 ? 0.19429 0.22738 0.16596 -0.00479 -0.01444 -0.00048 160 PHE A CA  
2084 C C   . PHE A 137 ? 0.19086 0.22571 0.16178 -0.00696 -0.01746 -0.00512 160 PHE A C   
2085 O O   . PHE A 137 ? 0.19687 0.23306 0.16246 -0.00525 -0.02358 -0.00603 160 PHE A O   
2086 C CB  . PHE A 137 ? 0.17185 0.19907 0.13164 -0.00312 -0.01257 0.00353  160 PHE A CB  
2087 C CG  . PHE A 137 ? 0.22111 0.24395 0.17441 -0.00525 -0.00883 0.00217  160 PHE A CG  
2088 C CD1 . PHE A 137 ? 0.25644 0.27851 0.20290 -0.00605 -0.01065 -0.00063 160 PHE A CD1 
2089 C CD2 . PHE A 137 ? 0.22611 0.24528 0.18021 -0.00600 -0.00416 0.00327  160 PHE A CD2 
2090 C CE1 . PHE A 137 ? 0.20241 0.22016 0.14425 -0.00766 -0.00693 -0.00210 160 PHE A CE1 
2091 C CE2 . PHE A 137 ? 0.23082 0.24602 0.18059 -0.00730 -0.00144 0.00221  160 PHE A CE2 
2092 C CZ  . PHE A 137 ? 0.24355 0.25800 0.18787 -0.00821 -0.00227 -0.00036 160 PHE A CZ  
2102 N N   . ARG A 138 ? 0.19092 0.22475 0.16617 -0.01053 -0.01330 -0.00811 161 ARG A N   
2103 C CA  . ARG A 138 ? 0.20753 0.24095 0.18144 -0.01296 -0.01501 -0.01265 161 ARG A CA  
2104 C C   . ARG A 138 ? 0.24280 0.26980 0.21246 -0.01534 -0.00884 -0.01269 161 ARG A C   
2105 O O   . ARG A 138 ? 0.24721 0.27205 0.22101 -0.01674 -0.00361 -0.01145 161 ARG A O   
2106 C CB  . ARG A 138 ? 0.22210 0.26199 0.21110 -0.01529 -0.01799 -0.01774 161 ARG A CB  
2107 C CG  . ARG A 138 ? 0.19567 0.23702 0.19753 -0.01757 -0.01176 -0.01771 161 ARG A CG  
2108 C CD  . ARG A 138 ? 0.19108 0.24024 0.21119 -0.01944 -0.01479 -0.02266 161 ARG A CD  
2109 N NE  . ARG A 138 ? 0.19178 0.23968 0.21569 -0.02333 -0.01461 -0.02755 161 ARG A NE  
2110 C CZ  . ARG A 138 ? 0.17595 0.22967 0.21766 -0.02627 -0.01661 -0.03320 161 ARG A CZ  
2111 N NH1 . ARG A 138 ? 0.20701 0.26934 0.26534 -0.02546 -0.01984 -0.03501 161 ARG A NH1 
2112 N NH2 . ARG A 138 ? 0.25511 0.30591 0.30008 -0.03015 -0.01512 -0.03739 161 ARG A NH2 
2126 N N   . LEU A 139 ? 0.23108 0.25425 0.19128 -0.01524 -0.00946 -0.01395 162 LEU A N   
2127 C CA  . LEU A 139 ? 0.21076 0.22792 0.16840 -0.01715 -0.00484 -0.01481 162 LEU A CA  
2128 C C   . LEU A 139 ? 0.23445 0.25200 0.19551 -0.01981 -0.00708 -0.02085 162 LEU A C   
2129 O O   . LEU A 139 ? 0.21375 0.23288 0.16933 -0.01876 -0.01220 -0.02410 162 LEU A O   
2130 C CB  . LEU A 139 ? 0.21562 0.22798 0.16271 -0.01493 -0.00280 -0.01223 162 LEU A CB  
2131 C CG  . LEU A 139 ? 0.22080 0.22699 0.16786 -0.01615 0.00177  -0.01230 162 LEU A CG  
2132 C CD1 . LEU A 139 ? 0.22063 0.22480 0.17159 -0.01629 0.00468  -0.00893 162 LEU A CD1 
2133 C CD2 . LEU A 139 ? 0.25730 0.25993 0.19706 -0.01409 0.00360  -0.01137 162 LEU A CD2 
2145 N N   . ASP A 140 ? 0.21454 0.23033 0.18463 -0.02314 -0.00345 -0.02248 163 ASP A N   
2146 C CA  . ASP A 140 ? 0.20103 0.21765 0.17984 -0.02657 -0.00493 -0.02860 163 ASP A CA  
2147 C C   . ASP A 140 ? 0.20870 0.21750 0.18488 -0.02830 -0.00112 -0.03028 163 ASP A C   
2148 O O   . ASP A 140 ? 0.24362 0.25180 0.22192 -0.03004 -0.00378 -0.03637 163 ASP A O   
2149 C CB  . ASP A 140 ? 0.23782 0.25758 0.23252 -0.02978 -0.00200 -0.02934 163 ASP A CB  
2150 C CG  . ASP A 140 ? 0.33028 0.35922 0.33385 -0.02873 -0.00659 -0.03010 163 ASP A CG  
2151 O OD1 . ASP A 140 ? 0.19369 0.22401 0.19292 -0.02581 -0.00602 -0.02537 163 ASP A OD1 
2152 O OD2 . ASP A 140 ? 0.36452 0.39917 0.38159 -0.03093 -0.01064 -0.03572 163 ASP A OD2 
2157 N N   . ARG A 141 ? 0.22991 0.23243 0.20213 -0.02761 0.00449  -0.02532 164 ARG A N   
2158 C CA  . ARG A 141 ? 0.19961 0.19380 0.17155 -0.02894 0.00858  -0.02571 164 ARG A CA  
2159 C C   . ARG A 141 ? 0.19223 0.18167 0.15410 -0.02550 0.00990  -0.02204 164 ARG A C   
2160 O O   . ARG A 141 ? 0.22820 0.22043 0.18458 -0.02267 0.00872  -0.01868 164 ARG A O   
2161 C CB  . ARG A 141 ? 0.21222 0.20184 0.19136 -0.03151 0.01440  -0.02292 164 ARG A CB  
2162 C CG  . ARG A 141 ? 0.22893 0.22217 0.22250 -0.03584 0.01483  -0.02753 164 ARG A CG  
2163 C CD  . ARG A 141 ? 0.27648 0.26533 0.27672 -0.03827 0.02265  -0.02363 164 ARG A CD  
2164 N NE  . ARG A 141 ? 0.26880 0.26070 0.26484 -0.03599 0.02401  -0.01901 164 ARG A NE  
2165 C CZ  . ARG A 141 ? 0.23194 0.21961 0.22841 -0.03671 0.03115  -0.01481 164 ARG A CZ  
2166 N NH1 . ARG A 141 ? 0.21751 0.19734 0.21871 -0.03984 0.03837  -0.01363 164 ARG A NH1 
2167 N NH2 . ARG A 141 ? 0.22584 0.21603 0.21696 -0.03412 0.03165  -0.01165 164 ARG A NH2 
2181 N N   . THR A 142 ? 0.22773 0.20997 0.18945 -0.02586 0.01237  -0.02317 165 THR A N   
2182 C CA  . THR A 142 ? 0.22697 0.20414 0.18337 -0.02277 0.01392  -0.02024 165 THR A CA  
2183 C C   . THR A 142 ? 0.22156 0.19260 0.17791 -0.02193 0.01652  -0.01456 165 THR A C   
2184 O O   . THR A 142 ? 0.24065 0.21051 0.19937 -0.02386 0.01852  -0.01260 165 THR A O   
2185 C CB  . THR A 142 ? 0.22252 0.19468 0.17966 -0.02301 0.01501  -0.02483 165 THR A CB  
2186 O OG1 . THR A 142 ? 0.22255 0.18904 0.18673 -0.02609 0.01722  -0.02636 165 THR A OG1 
2187 C CG2 . THR A 142 ? 0.23259 0.20914 0.18577 -0.02313 0.01236  -0.03095 165 THR A CG2 
2195 N N   . GLU A 143 ? 0.23461 0.20143 0.18792 -0.01865 0.01649  -0.01192 166 GLU A N   
2196 C CA  . GLU A 143 ? 0.25194 0.21113 0.20312 -0.01704 0.01750  -0.00688 166 GLU A CA  
2197 C C   . GLU A 143 ? 0.23748 0.18750 0.19170 -0.01839 0.02034  -0.00724 166 GLU A C   
2198 O O   . GLU A 143 ? 0.24640 0.19521 0.20468 -0.01877 0.02070  -0.01139 166 GLU A O   
2199 C CB  . GLU A 143 ? 0.23659 0.19496 0.18591 -0.01274 0.01489  -0.00456 166 GLU A CB  
2200 C CG  . GLU A 143 ? 0.25968 0.22595 0.20773 -0.01139 0.01260  -0.00404 166 GLU A CG  
2201 C CD  . GLU A 143 ? 0.25174 0.21811 0.19543 -0.01089 0.01152  -0.00063 166 GLU A CD  
2202 O OE1 . GLU A 143 ? 0.22975 0.18973 0.16977 -0.01152 0.01320  0.00163  166 GLU A OE1 
2203 O OE2 . GLU A 143 ? 0.22149 0.19331 0.16501 -0.00974 0.00962  -0.00015 166 GLU A OE2 
2210 N N   . PRO A 144 ? 0.28103 0.22322 0.23257 -0.01876 0.02292  -0.00270 167 PRO A N   
2211 C CA  . PRO A 144 ? 0.27727 0.21866 0.22142 -0.01753 0.02313  0.00214  167 PRO A CA  
2212 C C   . PRO A 144 ? 0.30825 0.25334 0.25486 -0.02138 0.02702  0.00161  167 PRO A C   
2213 O O   . PRO A 144 ? 0.28465 0.22909 0.22507 -0.02045 0.02828  0.00494  167 PRO A O   
2214 C CB  . PRO A 144 ? 0.28304 0.21127 0.22070 -0.01497 0.02426  0.00758  167 PRO A CB  
2215 C CG  . PRO A 144 ? 0.31427 0.23659 0.25937 -0.01803 0.02832  0.00576  167 PRO A CG  
2216 C CD  . PRO A 144 ? 0.26329 0.19435 0.21709 -0.01941 0.02609  -0.00139 167 PRO A CD  
2224 N N   . THR A 145 ? 0.25407 0.20355 0.21043 -0.02549 0.02860  -0.00318 168 THR A N   
2225 C CA  . THR A 145 ? 0.24307 0.19558 0.20574 -0.02930 0.03275  -0.00388 168 THR A CA  
2226 C C   . THR A 145 ? 0.21162 0.17473 0.17452 -0.02872 0.03030  -0.00477 168 THR A C   
2227 O O   . THR A 145 ? 0.28035 0.24576 0.24781 -0.03079 0.03424  -0.00432 168 THR A O   
2228 C CB  . THR A 145 ? 0.32617 0.28081 0.30205 -0.03386 0.03374  -0.00987 168 THR A CB  
2229 O OG1 . THR A 145 ? 0.25675 0.22004 0.23508 -0.03355 0.02748  -0.01594 168 THR A OG1 
2230 C CG2 . THR A 145 ? 0.38909 0.33209 0.36663 -0.03482 0.03730  -0.00890 168 THR A CG2 
2238 N N   . LEU A 146 ? 0.23124 0.20034 0.19023 -0.02585 0.02472  -0.00575 169 LEU A N   
2239 C CA  . LEU A 146 ? 0.24683 0.22500 0.20702 -0.02521 0.02250  -0.00629 169 LEU A CA  
2240 C C   . LEU A 146 ? 0.22734 0.20274 0.18137 -0.02348 0.02526  -0.00199 169 LEU A C   
2241 O O   . LEU A 146 ? 0.24274 0.22486 0.19906 -0.02300 0.02440  -0.00248 169 LEU A O   
2242 C CB  . LEU A 146 ? 0.24656 0.23012 0.20358 -0.02256 0.01700  -0.00760 169 LEU A CB  
2243 C CG  . LEU A 146 ? 0.20073 0.18068 0.15035 -0.01885 0.01543  -0.00450 169 LEU A CG  
2244 C CD1 . LEU A 146 ? 0.25255 0.23534 0.19932 -0.01684 0.01445  -0.00196 169 LEU A CD1 
2245 C CD2 . LEU A 146 ? 0.22660 0.20946 0.17591 -0.01755 0.01271  -0.00677 169 LEU A CD2 
2257 N N   . ASN A 147 ? 0.27513 0.24009 0.22077 -0.02224 0.02836  0.00201  170 ASN A N   
2258 C CA  . ASN A 147 ? 0.29558 0.25582 0.23141 -0.01995 0.03055  0.00569  170 ASN A CA  
2259 C C   . ASN A 147 ? 0.29208 0.24660 0.22720 -0.02230 0.03904  0.00774  170 ASN A C   
2260 O O   . ASN A 147 ? 0.27950 0.22717 0.20268 -0.02005 0.04188  0.01108  170 ASN A O   
2261 C CB  . ASN A 147 ? 0.26849 0.21989 0.19255 -0.01590 0.02723  0.00903  170 ASN A CB  
2262 C CG  . ASN A 147 ? 0.29804 0.25468 0.22515 -0.01372 0.02034  0.00705  170 ASN A CG  
2263 O OD1 . ASN A 147 ? 0.28108 0.24423 0.20915 -0.01227 0.01700  0.00590  170 ASN A OD1 
2264 N ND2 . ASN A 147 ? 0.29432 0.24784 0.22412 -0.01361 0.01917  0.00655  170 ASN A ND2 
2271 N N   . THR A 148 ? 0.23376 0.19052 0.18139 -0.02674 0.04354  0.00552  171 THR A N   
2272 C CA  . THR A 148 ? 0.23771 0.18808 0.18643 -0.02934 0.05353  0.00790  171 THR A CA  
2273 C C   . THR A 148 ? 0.23450 0.18884 0.18230 -0.02870 0.05753  0.00793  171 THR A C   
2274 O O   . THR A 148 ? 0.24884 0.19439 0.18823 -0.02859 0.06613  0.01154  171 THR A O   
2275 C CB  . THR A 148 ? 0.24898 0.20247 0.21588 -0.03471 0.05717  0.00434  171 THR A CB  
2276 O OG1 . THR A 148 ? 0.25718 0.22477 0.23827 -0.03612 0.05099  -0.00186 171 THR A OG1 
2277 C CG2 . THR A 148 ? 0.30024 0.24581 0.26628 -0.03533 0.05588  0.00491  171 THR A CG2 
2285 N N   . ALA A 149 ? 0.23027 0.19662 0.18569 -0.02798 0.05206  0.00417  172 ALA A N   
2286 C CA  . ALA A 149 ? 0.25793 0.22834 0.21285 -0.02650 0.05455  0.00368  172 ALA A CA  
2287 C C   . ALA A 149 ? 0.30075 0.26958 0.26333 -0.02951 0.06602  0.00383  172 ALA A C   
2288 O O   . ALA A 149 ? 0.27824 0.24225 0.23174 -0.02783 0.07245  0.00558  172 ALA A O   
2289 C CB  . ALA A 149 ? 0.25999 0.22324 0.19547 -0.02174 0.05214  0.00657  172 ALA A CB  
2295 N N   . ILE A 150 ? 0.25276 0.22586 0.23328 -0.03406 0.06895  0.00131  173 ILE A N   
2296 C CA  . ILE A 150 ? 0.24389 0.21626 0.23648 -0.03766 0.08096  0.00106  173 ILE A CA  
2297 C C   . ILE A 150 ? 0.28192 0.26564 0.28711 -0.03701 0.08157  -0.00259 173 ILE A C   
2298 O O   . ILE A 150 ? 0.26058 0.25660 0.27851 -0.03662 0.07223  -0.00686 173 ILE A O   
2299 C CB  . ILE A 150 ? 0.31592 0.29080 0.32819 -0.04299 0.08273  -0.00177 173 ILE A CB  
2300 C CG1 . ILE A 150 ? 0.29565 0.25789 0.29578 -0.04332 0.08302  0.00206  173 ILE A CG1 
2301 C CG2 . ILE A 150 ? 0.35131 0.32725 0.38092 -0.04708 0.09557  -0.00268 173 ILE A CG2 
2302 C CD1 . ILE A 150 ? 0.32814 0.29363 0.34689 -0.04796 0.08054  -0.00236 173 ILE A CD1 
2314 N N   . PRO A 151 ? 0.25155 0.23117 0.25380 -0.03663 0.09253  -0.00113 174 PRO A N   
2315 C CA  . PRO A 151 ? 0.30156 0.29220 0.31904 -0.03596 0.09388  -0.00514 174 PRO A CA  
2316 C C   . PRO A 151 ? 0.22893 0.23299 0.27726 -0.03992 0.09166  -0.01047 174 PRO A C   
2317 O O   . PRO A 151 ? 0.31051 0.31300 0.37126 -0.04451 0.09733  -0.01104 174 PRO A O   
2318 C CB  . PRO A 151 ? 0.31622 0.29744 0.32562 -0.03592 0.10949  -0.00262 174 PRO A CB  
2319 C CG  . PRO A 151 ? 0.35123 0.31593 0.33020 -0.03353 0.11058  0.00335  174 PRO A CG  
2320 C CD  . PRO A 151 ? 0.35270 0.31615 0.33387 -0.03567 0.10358  0.00451  174 PRO A CD  
2328 N N   . GLY A 152 ? 0.25192 0.26868 0.31252 -0.03789 0.08231  -0.01444 175 GLY A N   
2329 C CA  . GLY A 152 ? 0.36667 0.39688 0.45539 -0.04045 0.07680  -0.02005 175 GLY A CA  
2330 C C   . GLY A 152 ? 0.31874 0.35274 0.40757 -0.04088 0.06346  -0.02205 175 GLY A C   
2331 O O   . GLY A 152 ? 0.30439 0.34984 0.41317 -0.04174 0.05546  -0.02721 175 GLY A O   
2335 N N   . ASP A 153 ? 0.25076 0.27538 0.31823 -0.04003 0.06067  -0.01856 176 ASP A N   
2336 C CA  . ASP A 153 ? 0.21102 0.23773 0.27741 -0.04057 0.04996  -0.02080 176 ASP A CA  
2337 C C   . ASP A 153 ? 0.25000 0.28147 0.30621 -0.03584 0.03848  -0.02054 176 ASP A C   
2338 O O   . ASP A 153 ? 0.23264 0.25831 0.27087 -0.03250 0.03887  -0.01637 176 ASP A O   
2339 C CB  . ASP A 153 ? 0.23632 0.25031 0.28694 -0.04182 0.05364  -0.01723 176 ASP A CB  
2340 C CG  . ASP A 153 ? 0.26073 0.27553 0.31176 -0.04296 0.04504  -0.02033 176 ASP A CG  
2341 O OD1 . ASP A 153 ? 0.28468 0.30916 0.34306 -0.04204 0.03501  -0.02481 176 ASP A OD1 
2342 O OD2 . ASP A 153 ? 0.28720 0.29195 0.32988 -0.04437 0.04840  -0.01819 176 ASP A OD2 
2347 N N   . PRO A 154 ? 0.20299 0.24435 0.27000 -0.03522 0.02818  -0.02481 177 PRO A N   
2348 C CA  . PRO A 154 ? 0.18571 0.23000 0.24177 -0.03053 0.01865  -0.02344 177 PRO A CA  
2349 C C   . PRO A 154 ? 0.23538 0.27373 0.27344 -0.02945 0.01372  -0.02189 177 PRO A C   
2350 O O   . PRO A 154 ? 0.22666 0.26535 0.25368 -0.02573 0.00807  -0.01970 177 PRO A O   
2351 C CB  . PRO A 154 ? 0.23460 0.29078 0.30894 -0.02997 0.00974  -0.02840 177 PRO A CB  
2352 C CG  . PRO A 154 ? 0.20136 0.25931 0.29030 -0.03478 0.01035  -0.03357 177 PRO A CG  
2353 C CD  . PRO A 154 ? 0.24057 0.29102 0.33136 -0.03837 0.02463  -0.03115 177 PRO A CD  
2361 N N   . ARG A 155 ? 0.17421 0.20655 0.20977 -0.03251 0.01658  -0.02279 178 ARG A N   
2362 C CA  . ARG A 155 ? 0.17516 0.20234 0.19588 -0.03133 0.01230  -0.02212 178 ARG A CA  
2363 C C   . ARG A 155 ? 0.26620 0.28711 0.26988 -0.02793 0.01401  -0.01658 178 ARG A C   
2364 O O   . ARG A 155 ? 0.22932 0.24501 0.22890 -0.02768 0.02050  -0.01322 178 ARG A O   
2365 C CB  . ARG A 155 ? 0.19723 0.21808 0.22019 -0.03517 0.01609  -0.02409 178 ARG A CB  
2366 C CG  . ARG A 155 ? 0.22585 0.25258 0.26715 -0.03895 0.01344  -0.03082 178 ARG A CG  
2367 C CD  . ARG A 155 ? 0.22842 0.24735 0.27195 -0.04278 0.01762  -0.03270 178 ARG A CD  
2368 N NE  . ARG A 155 ? 0.26525 0.27672 0.31137 -0.04511 0.02911  -0.02835 178 ARG A NE  
2369 C CZ  . ARG A 155 ? 0.26905 0.27163 0.31745 -0.04835 0.03528  -0.02795 178 ARG A CZ  
2370 N NH1 . ARG A 155 ? 0.24700 0.24700 0.29597 -0.04969 0.03112  -0.03214 178 ARG A NH1 
2371 N NH2 . ARG A 155 ? 0.20810 0.20324 0.25755 -0.05010 0.04638  -0.02318 178 ARG A NH2 
2385 N N   . ASP A 156 ? 0.17877 0.19984 0.17239 -0.02518 0.00816  -0.01592 179 ASP A N   
2386 C CA  . ASP A 156 ? 0.20125 0.21650 0.18154 -0.02238 0.00932  -0.01155 179 ASP A CA  
2387 C C   . ASP A 156 ? 0.20138 0.21750 0.18141 -0.02032 0.01142  -0.00867 179 ASP A C   
2388 O O   . ASP A 156 ? 0.19520 0.20514 0.16741 -0.01915 0.01469  -0.00585 179 ASP A O   
2389 C CB  . ASP A 156 ? 0.23023 0.23645 0.20448 -0.02358 0.01377  -0.01021 179 ASP A CB  
2390 C CG  . ASP A 156 ? 0.19226 0.19705 0.16873 -0.02585 0.01244  -0.01386 179 ASP A CG  
2391 O OD1 . ASP A 156 ? 0.21005 0.21586 0.18110 -0.02431 0.00814  -0.01525 179 ASP A OD1 
2392 O OD2 . ASP A 156 ? 0.19595 0.19793 0.17947 -0.02914 0.01637  -0.01541 179 ASP A OD2 
2397 N N   . THR A 157 ? 0.16629 0.18984 0.15505 -0.01952 0.00884  -0.00985 180 THR A N   
2398 C CA  . THR A 157 ? 0.17830 0.20327 0.16886 -0.01737 0.01059  -0.00807 180 THR A CA  
2399 C C   . THR A 157 ? 0.19528 0.22432 0.18500 -0.01401 0.00459  -0.00670 180 THR A C   
2400 O O   . THR A 157 ? 0.19350 0.22545 0.18216 -0.01329 -0.00108 -0.00729 180 THR A O   
2401 C CB  . THR A 157 ? 0.22965 0.25938 0.23426 -0.01895 0.01438  -0.01034 180 THR A CB  
2402 O OG1 . THR A 157 ? 0.20017 0.23847 0.21711 -0.01928 0.00842  -0.01349 180 THR A OG1 
2403 C CG2 . THR A 157 ? 0.18641 0.21124 0.19281 -0.02248 0.02223  -0.01099 180 THR A CG2 
2411 N N   . THR A 158 ? 0.15851 0.18679 0.14798 -0.01178 0.00616  -0.00488 181 THR A N   
2412 C CA  . THR A 158 ? 0.16981 0.20168 0.16230 -0.00862 0.00195  -0.00332 181 THR A CA  
2413 C C   . THR A 158 ? 0.18939 0.22118 0.18732 -0.00739 0.00588  -0.00360 181 THR A C   
2414 O O   . THR A 158 ? 0.18964 0.21835 0.18680 -0.00891 0.01188  -0.00496 181 THR A O   
2415 C CB  . THR A 158 ? 0.19062 0.21860 0.17294 -0.00671 -0.00061 -0.00014 181 THR A CB  
2416 O OG1 . THR A 158 ? 0.18221 0.21315 0.16714 -0.00382 -0.00493 0.00201  181 THR A OG1 
2417 C CG2 . THR A 158 ? 0.16881 0.19103 0.14596 -0.00610 0.00268  0.00104  181 THR A CG2 
2425 N N   . SER A 159 ? 0.18298 0.21740 0.18593 -0.00437 0.00287  -0.00229 182 SER A N   
2426 C CA  . SER A 159 ? 0.15546 0.18940 0.16402 -0.00276 0.00645  -0.00320 182 SER A CA  
2427 C C   . SER A 159 ? 0.20608 0.23398 0.20655 -0.00096 0.00623  -0.00128 182 SER A C   
2428 O O   . SER A 159 ? 0.22109 0.24705 0.21570 -0.00042 0.00284  0.00150  182 SER A O   
2429 C CB  . SER A 159 ? 0.17856 0.21922 0.20131 -0.00028 0.00322  -0.00349 182 SER A CB  
2430 O OG  . SER A 159 ? 0.18184 0.22151 0.20131 0.00255  -0.00243 0.00030  182 SER A OG  
2436 N N   . PRO A 160 ? 0.20601 0.23066 0.20674 0.00005  0.00998  -0.00316 183 PRO A N   
2437 C CA  . PRO A 160 ? 0.17326 0.19269 0.16936 0.00175  0.00856  -0.00235 183 PRO A CA  
2438 C C   . PRO A 160 ? 0.17850 0.19956 0.18130 0.00410  0.00454  0.00073  183 PRO A C   
2439 O O   . PRO A 160 ? 0.21941 0.23711 0.21846 0.00441  0.00264  0.00311  183 PRO A O   
2440 C CB  . PRO A 160 ? 0.17548 0.19137 0.17103 0.00264  0.01314  -0.00627 183 PRO A CB  
2441 C CG  . PRO A 160 ? 0.22111 0.23713 0.21334 0.00045  0.01850  -0.00799 183 PRO A CG  
2442 C CD  . PRO A 160 ? 0.21052 0.23455 0.21339 -0.00072 0.01650  -0.00658 183 PRO A CD  
2450 N N   . ARG A 161 ? 0.18691 0.21270 0.20038 0.00593  0.00343  0.00105  184 ARG A N   
2451 C CA  . ARG A 161 ? 0.15780 0.18373 0.17643 0.00874  -0.00047 0.00501  184 ARG A CA  
2452 C C   . ARG A 161 ? 0.21613 0.24145 0.22670 0.00842  -0.00400 0.00951  184 ARG A C   
2453 O O   . ARG A 161 ? 0.21843 0.23959 0.22654 0.00963  -0.00473 0.01340  184 ARG A O   
2454 C CB  . ARG A 161 ? 0.15875 0.19039 0.19035 0.01115  -0.00224 0.00463  184 ARG A CB  
2455 C CG  . ARG A 161 ? 0.21880 0.24913 0.25610 0.01505  -0.00632 0.00931  184 ARG A CG  
2456 C CD  . ARG A 161 ? 0.23017 0.26699 0.27928 0.01806  -0.01104 0.01001  184 ARG A CD  
2457 N NE  . ARG A 161 ? 0.22039 0.26159 0.28428 0.01875  -0.00775 0.00497  184 ARG A NE  
2458 C CZ  . ARG A 161 ? 0.32967 0.36960 0.40492 0.02190  -0.00652 0.00437  184 ARG A CZ  
2459 N NH1 . ARG A 161 ? 0.26269 0.29646 0.33675 0.02441  -0.00824 0.00864  184 ARG A NH1 
2460 N NH2 . ARG A 161 ? 0.24261 0.28726 0.33198 0.02255  -0.00278 -0.00072 184 ARG A NH2 
2474 N N   . ALA A 162 ? 0.20241 0.23151 0.20946 0.00684  -0.00567 0.00882  185 ALA A N   
2475 C CA  . ALA A 162 ? 0.21759 0.24566 0.21536 0.00683  -0.00877 0.01219  185 ALA A CA  
2476 C C   . ALA A 162 ? 0.17827 0.20087 0.16708 0.00511  -0.00575 0.01313  185 ALA A C   
2477 O O   . ALA A 162 ? 0.21424 0.23354 0.19749 0.00607  -0.00604 0.01709  185 ALA A O   
2478 C CB  . ALA A 162 ? 0.19931 0.23225 0.19593 0.00521  -0.01145 0.00968  185 ALA A CB  
2484 N N   A MET A 163 ? 0.18657 0.20779 0.17382 0.00278  -0.00266 0.00968  186 MET A N   
2485 N N   B MET A 163 ? 0.18606 0.20727 0.17332 0.00278  -0.00266 0.00968  186 MET A N   
2486 C CA  A MET A 163 ? 0.20938 0.22612 0.19025 0.00156  -0.00100 0.01017  186 MET A CA  
2487 C CA  B MET A 163 ? 0.20942 0.22616 0.19032 0.00157  -0.00100 0.01017  186 MET A CA  
2488 C C   A MET A 163 ? 0.20528 0.21823 0.19023 0.00289  -0.00016 0.01178  186 MET A C   
2489 C C   B MET A 163 ? 0.20522 0.21819 0.19019 0.00290  -0.00017 0.01182  186 MET A C   
2490 O O   A MET A 163 ? 0.20085 0.21096 0.18392 0.00258  0.00084  0.01379  186 MET A O   
2491 O O   B MET A 163 ? 0.20101 0.21113 0.18406 0.00260  0.00084  0.01387  186 MET A O   
2492 C CB  A MET A 163 ? 0.18379 0.19901 0.16112 -0.00053 0.00096  0.00654  186 MET A CB  
2493 C CB  B MET A 163 ? 0.18314 0.19835 0.16050 -0.00053 0.00097  0.00653  186 MET A CB  
2494 C CG  A MET A 163 ? 0.16937 0.18067 0.14134 -0.00143 0.00147  0.00676  186 MET A CG  
2495 C CG  B MET A 163 ? 0.16768 0.17922 0.13919 -0.00159 0.00147  0.00674  186 MET A CG  
2496 S SD  A MET A 163 ? 0.21859 0.23062 0.18524 -0.00211 0.00118  0.00899  186 MET A SD  
2497 S SD  B MET A 163 ? 0.21413 0.22694 0.18021 -0.00236 0.00094  0.00866  186 MET A SD  
2498 C CE  A MET A 163 ? 0.16833 0.17971 0.13024 -0.00450 0.00195  0.00588  186 MET A CE  
2499 C CE  B MET A 163 ? 0.22666 0.23633 0.19345 -0.00112 0.00239  0.01206  186 MET A CE  
2518 N N   . ALA A 164 ? 0.18412 0.19691 0.17624 0.00426  -0.00007 0.01047  187 ALA A N   
2519 C CA  . ALA A 164 ? 0.15813 0.16702 0.15639 0.00536  0.00048  0.01133  187 ALA A CA  
2520 C C   . ALA A 164 ? 0.22947 0.23712 0.22948 0.00692  0.00042  0.01733  187 ALA A C   
2521 O O   . ALA A 164 ? 0.19553 0.19947 0.19713 0.00660  0.00230  0.01980  187 ALA A O   
2522 C CB  . ALA A 164 ? 0.21545 0.22385 0.22061 0.00664  0.00079  0.00767  187 ALA A CB  
2529 N N   . GLN A 165 ? 0.19265 0.20301 0.19200 0.00874  -0.00164 0.01992  188 GLN A N   
2530 C CA  . GLN A 165 ? 0.20385 0.21143 0.20110 0.01098  -0.00211 0.02648  188 GLN A CA  
2531 C C   . GLN A 165 ? 0.22398 0.22947 0.21048 0.00976  -0.00029 0.02915  188 GLN A C   
2532 O O   . GLN A 165 ? 0.22959 0.22994 0.21467 0.01044  0.00288  0.03405  188 GLN A O   
2533 C CB  . GLN A 165 ? 0.19350 0.20466 0.19141 0.01379  -0.00660 0.02812  188 GLN A CB  
2534 C CG  . GLN A 165 ? 0.17455 0.18703 0.18500 0.01569  -0.00738 0.02633  188 GLN A CG  
2535 C CD  . GLN A 165 ? 0.39754 0.40369 0.41439 0.01814  -0.00597 0.03108  188 GLN A CD  
2536 O OE1 . GLN A 165 ? 0.31116 0.31172 0.32284 0.01816  -0.00371 0.03630  188 GLN A OE1 
2537 N NE2 . GLN A 165 ? 0.50368 0.51022 0.53265 0.02015  -0.00645 0.02920  188 GLN A NE2 
2546 N N   . THR A 166 ? 0.22606 0.23483 0.20563 0.00788  -0.00126 0.02588  189 THR A N   
2547 C CA  . THR A 166 ? 0.18620 0.19275 0.15590 0.00687  0.00098  0.02745  189 THR A CA  
2548 C C   . THR A 166 ? 0.22271 0.22609 0.19701 0.00508  0.00555  0.02682  189 THR A C   
2549 O O   . THR A 166 ? 0.21725 0.21681 0.18894 0.00523  0.00964  0.03043  189 THR A O   
2550 C CB  . THR A 166 ? 0.20574 0.21614 0.16880 0.00529  -0.00136 0.02346  189 THR A CB  
2551 O OG1 . THR A 166 ? 0.24003 0.25335 0.20008 0.00728  -0.00632 0.02430  189 THR A OG1 
2552 C CG2 . THR A 166 ? 0.29808 0.30569 0.25187 0.00420  0.00172  0.02390  189 THR A CG2 
2560 N N   . LEU A 167 ? 0.19677 0.20124 0.17856 0.00373  0.00498  0.02231  190 LEU A N   
2561 C CA  . LEU A 167 ? 0.18035 0.18235 0.16839 0.00243  0.00749  0.02100  190 LEU A CA  
2562 C C   . LEU A 167 ? 0.18811 0.18638 0.18508 0.00324  0.01045  0.02469  190 LEU A C   
2563 O O   . LEU A 167 ? 0.24193 0.23786 0.24397 0.00229  0.01436  0.02588  190 LEU A O   
2564 C CB  . LEU A 167 ? 0.18799 0.19083 0.17995 0.00156  0.00483  0.01527  190 LEU A CB  
2565 C CG  . LEU A 167 ? 0.20591 0.20705 0.20354 0.00054  0.00520  0.01288  190 LEU A CG  
2566 C CD1 . LEU A 167 ? 0.25639 0.25796 0.24877 -0.00042 0.00681  0.01311  190 LEU A CD1 
2567 C CD2 . LEU A 167 ? 0.21596 0.21646 0.21449 0.00068  0.00107  0.00728  190 LEU A CD2 
2579 N N   A ARG A 168 ? 0.20715 0.20457 0.20779 0.00500  0.00922  0.02664  191 ARG A N   
2580 N N   C ARG A 168 ? 0.20733 0.20479 0.20825 0.00498  0.00915  0.02646  191 ARG A N   
2581 C CA  A ARG A 168 ? 0.22049 0.21311 0.23016 0.00579  0.01257  0.03084  191 ARG A CA  
2582 C CA  C ARG A 168 ? 0.22023 0.21287 0.22981 0.00584  0.01249  0.03088  191 ARG A CA  
2583 C C   A ARG A 168 ? 0.24017 0.22884 0.24217 0.00656  0.01747  0.03803  191 ARG A C   
2584 C C   C ARG A 168 ? 0.24014 0.22900 0.24192 0.00644  0.01746  0.03778  191 ARG A C   
2585 O O   A ARG A 168 ? 0.24433 0.22866 0.25335 0.00574  0.02320  0.04102  191 ARG A O   
2586 O O   C ARG A 168 ? 0.24391 0.22889 0.25238 0.00539  0.02317  0.04024  191 ARG A O   
2587 C CB  A ARG A 168 ? 0.21635 0.20828 0.23135 0.00802  0.01011  0.03159  191 ARG A CB  
2588 C CB  C ARG A 168 ? 0.21707 0.20896 0.23108 0.00825  0.01007  0.03219  191 ARG A CB  
2589 C CG  A ARG A 168 ? 0.21982 0.20559 0.24533 0.00881  0.01382  0.03616  191 ARG A CG  
2590 C CG  C ARG A 168 ? 0.22345 0.20887 0.24683 0.00929  0.01396  0.03760  191 ARG A CG  
2591 C CD  A ARG A 168 ? 0.25547 0.23723 0.27297 0.01175  0.01524  0.04485  191 ARG A CD  
2592 C CD  C ARG A 168 ? 0.18884 0.17237 0.21781 0.01230  0.01175  0.03973  191 ARG A CD  
2593 N NE  A ARG A 168 ? 0.27006 0.25440 0.28670 0.01464  0.00985  0.04454  191 ARG A NE  
2594 N NE  C ARG A 168 ? 0.24851 0.22466 0.28827 0.01277  0.01618  0.04451  191 ARG A NE  
2595 C CZ  A ARG A 168 ? 0.24170 0.22438 0.27033 0.01620  0.00874  0.04366  191 ARG A CZ  
2596 C CZ  C ARG A 168 ? 0.29300 0.26582 0.34385 0.01466  0.01544  0.04495  191 ARG A CZ  
2597 N NH1 A ARG A 168 ? 0.24898 0.22672 0.29063 0.01513  0.01224  0.04328  191 ARG A NH1 
2598 N NH1 C ARG A 168 ? 0.23986 0.21630 0.29191 0.01684  0.01065  0.04153  191 ARG A NH1 
2599 N NH2 A ARG A 168 ? 0.26139 0.24761 0.29074 0.01885  0.00409  0.04252  191 ARG A NH2 
2600 N NH2 C ARG A 168 ? 0.33952 0.30502 0.40219 0.01428  0.02028  0.04867  191 ARG A NH2 
2627 N N   . ASN A 169 ? 0.23462 0.22430 0.22223 0.00820  0.01551  0.04062  192 ASN A N   
2628 C CA  . ASN A 169 ? 0.24453 0.22943 0.21994 0.00940  0.01993  0.04689  192 ASN A CA  
2629 C C   . ASN A 169 ? 0.20227 0.18653 0.17699 0.00697  0.02574  0.04537  192 ASN A C   
2630 O O   . ASN A 169 ? 0.25198 0.23065 0.22586 0.00703  0.03327  0.05028  192 ASN A O   
2631 C CB  . ASN A 169 ? 0.26893 0.25597 0.22910 0.01162  0.01444  0.04756  192 ASN A CB  
2632 C CG  . ASN A 169 ? 0.32863 0.30934 0.27226 0.01407  0.01742  0.05425  192 ASN A CG  
2633 O OD1 . ASN A 169 ? 0.39683 0.37037 0.34015 0.01453  0.02477  0.06016  192 ASN A OD1 
2634 N ND2 . ASN A 169 ? 0.37107 0.35381 0.30018 0.01575  0.01181  0.05321  192 ASN A ND2 
2641 N N   . LEU A 170 ? 0.22939 0.21884 0.20564 0.00494  0.02299  0.03875  193 LEU A N   
2642 C CA  . LEU A 170 ? 0.22770 0.21701 0.20406 0.00315  0.02769  0.03683  193 LEU A CA  
2643 C C   . LEU A 170 ? 0.22680 0.21483 0.22114 0.00149  0.03224  0.03613  193 LEU A C   
2644 O O   . LEU A 170 ? 0.21381 0.19941 0.21096 0.00071  0.03953  0.03782  193 LEU A O   
2645 C CB  . LEU A 170 ? 0.22865 0.22291 0.20207 0.00191  0.02280  0.03051  193 LEU A CB  
2646 C CG  . LEU A 170 ? 0.20700 0.20304 0.16523 0.00258  0.01930  0.02952  193 LEU A CG  
2647 C CD1 . LEU A 170 ? 0.26300 0.26296 0.22297 0.00087  0.01544  0.02349  193 LEU A CD1 
2648 C CD2 . LEU A 170 ? 0.27611 0.26827 0.22198 0.00334  0.02459  0.03225  193 LEU A CD2 
2660 N N   . THR A 171 ? 0.22548 0.21516 0.23298 0.00094  0.02812  0.03289  194 THR A N   
2661 C CA  . THR A 171 ? 0.25947 0.24898 0.28578 -0.00077 0.03020  0.03016  194 THR A CA  
2662 C C   . THR A 171 ? 0.20630 0.19128 0.24509 -0.00083 0.03461  0.03416  194 THR A C   
2663 O O   . THR A 171 ? 0.28327 0.26711 0.33833 -0.00253 0.03942  0.03365  194 THR A O   
2664 C CB  . THR A 171 ? 0.18430 0.17744 0.21769 -0.00129 0.02232  0.02276  194 THR A CB  
2665 O OG1 . THR A 171 ? 0.19737 0.19017 0.22949 -0.00016 0.01802  0.02217  194 THR A OG1 
2666 C CG2 . THR A 171 ? 0.20176 0.19808 0.22461 -0.00136 0.01872  0.01924  194 THR A CG2 
2674 N N   . LEU A 172 ? 0.29782 0.14973 0.22542 0.00283  -0.03468 -0.01584 195 LEU A N   
2675 C CA  . LEU A 172 ? 0.36740 0.16743 0.28100 0.00378  -0.03736 -0.01105 195 LEU A CA  
2676 C C   . LEU A 172 ? 0.37018 0.14949 0.25841 0.01545  -0.02894 0.00647  195 LEU A C   
2677 O O   . LEU A 172 ? 0.39689 0.12688 0.27455 0.01127  -0.02435 0.01858  195 LEU A O   
2678 C CB  . LEU A 172 ? 0.40711 0.18562 0.30373 0.02251  -0.05143 -0.02679 195 LEU A CB  
2679 C CG  . LEU A 172 ? 0.32828 0.12323 0.23874 0.01790  -0.06176 -0.04528 195 LEU A CG  
2680 C CD1 . LEU A 172 ? 0.37353 0.14705 0.25711 0.04415  -0.07381 -0.06118 195 LEU A CD1 
2681 C CD2 . LEU A 172 ? 0.40297 0.18082 0.33877 -0.01004 -0.06605 -0.04854 195 LEU A CD2 
2693 N N   . GLY A 173 ? 0.38057 0.19433 0.25774 0.03050  -0.02771 0.00777  196 GLY A N   
2694 C CA  . GLY A 173 ? 0.39448 0.19781 0.24271 0.04684  -0.02290 0.02230  196 GLY A CA  
2695 C C   . GLY A 173 ? 0.41689 0.23426 0.26732 0.03433  -0.00925 0.03418  196 GLY A C   
2696 O O   . GLY A 173 ? 0.36308 0.18528 0.23856 0.01152  -0.00044 0.03624  196 GLY A O   
2700 N N   . LYS A 174 ? 0.40682 0.23524 0.22868 0.05345  -0.00862 0.04061  197 LYS A N   
2701 C CA  . LYS A 174 ? 0.43248 0.26501 0.24059 0.05083  0.00548  0.05384  197 LYS A CA  
2702 C C   . LYS A 174 ? 0.40580 0.28437 0.21077 0.05690  -0.00161 0.03850  197 LYS A C   
2703 O O   . LYS A 174 ? 0.42847 0.31145 0.20578 0.06735  0.00459  0.04513  197 LYS A O   
2704 C CB  . LYS A 174 ? 0.57732 0.37126 0.34269 0.07104  0.01401  0.07760  197 LYS A CB  
2705 C CG  . LYS A 174 ? 0.63022 0.36566 0.39753 0.06258  0.02176  0.09340  197 LYS A CG  
2706 C CD  . LYS A 174 ? 0.62692 0.32959 0.35599 0.09122  0.01983  0.10565  197 LYS A CD  
2707 C CE  . LYS A 174 ? 0.76962 0.41952 0.51180 0.07602  0.02803  0.11689  197 LYS A CE  
2708 N NZ  . LYS A 174 ? 0.84678 0.47764 0.61174 0.06591  0.01392  0.09780  197 LYS A NZ  
2722 N N   . ALA A 175 ? 0.39849 0.30894 0.22968 0.05053  -0.01387 0.01797  198 ALA A N   
2723 C CA  . ALA A 175 ? 0.35565 0.30301 0.19164 0.04830  -0.02000 0.00158  198 ALA A CA  
2724 C C   . ALA A 175 ? 0.34461 0.28837 0.17777 0.03775  -0.00592 0.00470  198 ALA A C   
2725 O O   . ALA A 175 ? 0.35069 0.30749 0.16395 0.04541  -0.00874 -0.00394 198 ALA A O   
2726 C CB  . ALA A 175 ? 0.28848 0.26255 0.16024 0.03585  -0.02771 -0.01481 198 ALA A CB  
2732 N N   . LEU A 176 ? 0.29263 0.22244 0.14645 0.02190  0.00762  0.01426  199 LEU A N   
2733 C CA  . LEU A 176 ? 0.29990 0.23251 0.15849 0.01392  0.02312  0.01849  199 LEU A CA  
2734 C C   . LEU A 176 ? 0.32398 0.23690 0.17371 0.01385  0.04180  0.04308  199 LEU A C   
2735 O O   . LEU A 176 ? 0.33316 0.22244 0.18544 0.01081  0.04257  0.05575  199 LEU A O   
2736 C CB  . LEU A 176 ? 0.27713 0.22022 0.17373 -0.00315 0.02402  0.01084  199 LEU A CB  
2737 C CG  . LEU A 176 ? 0.26239 0.22133 0.17068 -0.00627 0.01212  -0.00830 199 LEU A CG  
2738 C CD1 . LEU A 176 ? 0.26200 0.22556 0.19942 -0.01760 0.01563  -0.00953 199 LEU A CD1 
2739 C CD2 . LEU A 176 ? 0.30305 0.26768 0.19245 -0.00071 0.01136  -0.02029 199 LEU A CD2 
2751 N N   . GLY A 177 ? 0.35897 0.27910 0.19583 0.01855  0.05829  0.05042  200 GLY A N   
2752 C CA  . GLY A 177 ? 0.39480 0.30470 0.23358 0.01440  0.08186  0.07706  200 GLY A CA  
2753 C C   . GLY A 177 ? 0.34293 0.25465 0.23342 -0.01118 0.08540  0.08200  200 GLY A C   
2754 O O   . GLY A 177 ? 0.33768 0.26355 0.25699 -0.02095 0.07260  0.06490  200 GLY A O   
2758 N N   . ASP A 178 ? 0.41763 0.31575 0.31965 -0.02208 0.10355  0.10634  201 ASP A N   
2759 C CA  . ASP A 178 ? 0.41737 0.31649 0.37162 -0.04950 0.10262  0.10823  201 ASP A CA  
2760 C C   . ASP A 178 ? 0.31271 0.25578 0.30690 -0.05794 0.10250  0.09617  201 ASP A C   
2761 O O   . ASP A 178 ? 0.31419 0.26589 0.33977 -0.06998 0.08552  0.08065  201 ASP A O   
2762 C CB  . ASP A 178 ? 0.42103 0.31073 0.38743 -0.06206 0.11425  0.12849  201 ASP A CB  
2763 C CG  . ASP A 178 ? 0.53021 0.36917 0.47662 -0.06199 0.10623  0.13598  201 ASP A CG  
2764 O OD1 . ASP A 178 ? 0.52353 0.33730 0.44203 -0.04708 0.09219  0.12582  201 ASP A OD1 
2765 O OD2 . ASP A 178 ? 0.50363 0.32669 0.46151 -0.07644 0.11395  0.15139  201 ASP A OD2 
2770 N N   . SER A 179 ? 0.30643 0.27796 0.29485 -0.04667 0.11890  0.10116  202 SER A N   
2771 C CA  . SER A 179 ? 0.26836 0.27917 0.29057 -0.04842 0.11974  0.09111  202 SER A CA  
2772 C C   . SER A 179 ? 0.27337 0.28103 0.28745 -0.04102 0.09799  0.06660  202 SER A C   
2773 O O   . SER A 179 ? 0.24284 0.26907 0.28917 -0.04802 0.08744  0.05657  202 SER A O   
2774 C CB  . SER A 179 ? 0.31573 0.34993 0.32199 -0.03041 0.13754  0.09619  202 SER A CB  
2775 O OG  . SER A 179 ? 0.34071 0.40952 0.37427 -0.02600 0.13908  0.08739  202 SER A OG  
2781 N N   . GLN A 180 ? 0.31163 0.29787 0.28319 -0.02671 0.08972  0.05674  203 GLN A N   
2782 C CA  . GLN A 180 ? 0.27590 0.26021 0.24128 -0.02169 0.07279  0.03554  203 GLN A CA  
2783 C C   . GLN A 180 ? 0.27571 0.25199 0.25758 -0.03241 0.05431  0.02795  203 GLN A C   
2784 O O   . GLN A 180 ? 0.22919 0.21381 0.22449 -0.03327 0.04511  0.01674  203 GLN A O   
2785 C CB  . GLN A 180 ? 0.25199 0.22232 0.17421 -0.00684 0.06848  0.02566  203 GLN A CB  
2786 C CG  . GLN A 180 ? 0.29382 0.26869 0.19002 0.00938  0.08325  0.02528  203 GLN A CG  
2787 C CD  . GLN A 180 ? 0.35355 0.33114 0.23376 0.01676  0.10336  0.04708  203 GLN A CD  
2788 O OE1 . GLN A 180 ? 0.36960 0.33523 0.24656 0.01137  0.10408  0.06180  203 GLN A OE1 
2789 N NE2 . GLN A 180 ? 0.42283 0.41297 0.28897 0.03191  0.12209  0.05085  203 GLN A NE2 
2798 N N   . ARG A 181 ? 0.28155 0.23809 0.25741 -0.03705 0.04988  0.03471  204 ARG A N   
2799 C CA  A ARG A 181 ? 0.27936 0.22513 0.26613 -0.04312 0.03294  0.02605  204 ARG A CA  
2800 C CA  B ARG A 181 ? 0.27966 0.22547 0.26645 -0.04312 0.03295  0.02604  204 ARG A CA  
2801 C C   . ARG A 181 ? 0.27153 0.23260 0.29627 -0.05660 0.02911  0.02328  204 ARG A C   
2802 O O   . ARG A 181 ? 0.26932 0.23757 0.30147 -0.05488 0.01568  0.01037  204 ARG A O   
2803 C CB  A ARG A 181 ? 0.28768 0.20127 0.25748 -0.04227 0.03046  0.03451  204 ARG A CB  
2804 C CB  B ARG A 181 ? 0.28938 0.20308 0.25887 -0.04212 0.03061  0.03460  204 ARG A CB  
2805 C CG  A ARG A 181 ? 0.38089 0.27788 0.35881 -0.04572 0.01379  0.02406  204 ARG A CG  
2806 C CG  B ARG A 181 ? 0.38055 0.27684 0.35710 -0.04519 0.01406  0.02448  204 ARG A CG  
2807 C CD  A ARG A 181 ? 0.37875 0.23426 0.33562 -0.04134 0.01247  0.03289  204 ARG A CD  
2808 C CD  B ARG A 181 ? 0.38505 0.24201 0.33555 -0.03709 0.01211  0.03251  204 ARG A CD  
2809 N NE  A ARG A 181 ? 0.41704 0.25036 0.38913 -0.05900 0.02511  0.04990  204 ARG A NE  
2810 N NE  B ARG A 181 ? 0.44778 0.27823 0.40315 -0.04975 0.02649  0.05244  204 ARG A NE  
2811 C CZ  A ARG A 181 ? 0.45765 0.24362 0.41339 -0.05903 0.02824  0.06240  204 ARG A CZ  
2812 C CZ  B ARG A 181 ? 0.45313 0.27166 0.38318 -0.04145 0.04274  0.07258  204 ARG A CZ  
2813 N NH1 A ARG A 181 ? 0.59016 0.34800 0.50957 -0.03690 0.01883  0.05967  204 ARG A NH1 
2814 N NH1 B ARG A 181 ? 0.40190 0.23520 0.29916 -0.01989 0.04290  0.07147  204 ARG A NH1 
2815 N NH2 A ARG A 181 ? 0.56143 0.32926 0.54008 -0.08099 0.04182  0.07911  204 ARG A NH2 
2816 N NH2 B ARG A 181 ? 0.51021 0.30153 0.44776 -0.05533 0.05918  0.09437  204 ARG A NH2 
2843 N N   . ALA A 182 ? 0.23343 0.20412 0.28311 -0.06905 0.04089  0.03567  205 ALA A N   
2844 C CA  . ALA A 182 ? 0.23121 0.22729 0.32387 -0.08269 0.03458  0.03101  205 ALA A CA  
2845 C C   . ALA A 182 ? 0.22780 0.25482 0.32586 -0.07008 0.03149  0.02172  205 ALA A C   
2846 O O   . ALA A 182 ? 0.23311 0.27499 0.34826 -0.07066 0.01635  0.01048  205 ALA A O   
2847 C CB  . ALA A 182 ? 0.25383 0.26662 0.38038 -0.09962 0.05208  0.04841  205 ALA A CB  
2853 N N   . GLN A 183 ? 0.21015 0.24349 0.28971 -0.05616 0.04548  0.02600  206 GLN A N   
2854 C CA  . GLN A 183 ? 0.19442 0.24633 0.27530 -0.04229 0.04505  0.01933  206 GLN A CA  
2855 C C   . GLN A 183 ? 0.17914 0.21489 0.24220 -0.03612 0.03033  0.00739  206 GLN A C   
2856 O O   . GLN A 183 ? 0.17096 0.22080 0.24309 -0.02901 0.02311  0.00278  206 GLN A O   
2857 C CB  . GLN A 183 ? 0.23707 0.28680 0.29526 -0.02786 0.06250  0.02334  206 GLN A CB  
2858 C CG  . GLN A 183 ? 0.17154 0.22811 0.22624 -0.01131 0.06418  0.01747  206 GLN A CG  
2859 C CD  . GLN A 183 ? 0.20369 0.30125 0.29516 -0.00698 0.06588  0.02222  206 GLN A CD  
2860 O OE1 . GLN A 183 ? 0.24629 0.37013 0.35167 -0.00009 0.08157  0.03060  206 GLN A OE1 
2861 N NE2 . GLN A 183 ? 0.20621 0.31513 0.31414 -0.00907 0.04904  0.01652  206 GLN A NE2 
2870 N N   . LEU A 184 ? 0.20190 0.21236 0.23953 -0.03633 0.02680  0.00386  207 LEU A N   
2871 C CA  . LEU A 184 ? 0.24114 0.24318 0.26666 -0.03131 0.01677  -0.00480 207 LEU A CA  
2872 C C   . LEU A 184 ? 0.23241 0.24125 0.27021 -0.03262 0.00270  -0.00995 207 LEU A C   
2873 O O   . LEU A 184 ? 0.21012 0.22656 0.24528 -0.02348 -0.00198 -0.01350 207 LEU A O   
2874 C CB  . LEU A 184 ? 0.20035 0.18579 0.20493 -0.03132 0.01418  -0.00787 207 LEU A CB  
2875 C CG  . LEU A 184 ? 0.18868 0.17369 0.18681 -0.02723 0.00638  -0.01472 207 LEU A CG  
2876 C CD1 . LEU A 184 ? 0.24365 0.23164 0.24203 -0.02451 0.01319  -0.01526 207 LEU A CD1 
2877 C CD2 . LEU A 184 ? 0.25509 0.23563 0.23944 -0.02551 0.00267  -0.01811 207 LEU A CD2 
2889 N N   . VAL A 185 ? 0.18622 0.18873 0.23438 -0.04286 -0.00409 -0.01055 208 VAL A N   
2890 C CA  . VAL A 185 ? 0.20722 0.20944 0.26283 -0.04431 -0.02143 -0.02113 208 VAL A CA  
2891 C C   . VAL A 185 ? 0.18496 0.21882 0.26534 -0.04345 -0.02776 -0.02456 208 VAL A C   
2892 O O   . VAL A 185 ? 0.23872 0.28156 0.31264 -0.03234 -0.04094 -0.03409 208 VAL A O   
2893 C CB  . VAL A 185 ? 0.29699 0.27376 0.35738 -0.05792 -0.02655 -0.02155 208 VAL A CB  
2894 C CG1 . VAL A 185 ? 0.37857 0.34994 0.44842 -0.06207 -0.04727 -0.03736 208 VAL A CG1 
2895 C CG2 . VAL A 185 ? 0.29494 0.24366 0.32446 -0.04963 -0.02314 -0.01868 208 VAL A CG2 
2905 N N   . THR A 186 ? 0.19719 0.25339 0.30411 -0.05087 -0.01773 -0.01607 209 THR A N   
2906 C CA  . THR A 186 ? 0.20129 0.29763 0.33466 -0.04532 -0.02369 -0.01865 209 THR A CA  
2907 C C   . THR A 186 ? 0.20830 0.30879 0.31756 -0.02092 -0.02221 -0.01809 209 THR A C   
2908 O O   . THR A 186 ? 0.16577 0.28726 0.27754 -0.00837 -0.03603 -0.02468 209 THR A O   
2909 C CB  . THR A 186 ? 0.18164 0.30591 0.34672 -0.05311 -0.00755 -0.00665 209 THR A CB  
2910 O OG1 . THR A 186 ? 0.26101 0.38184 0.45352 -0.07863 -0.00786 -0.00425 209 THR A OG1 
2911 C CG2 . THR A 186 ? 0.14422 0.31944 0.33761 -0.04023 -0.01207 -0.00797 209 THR A CG2 
2919 N N   . TRP A 187 ? 0.17259 0.25149 0.25726 -0.01357 -0.00584 -0.01019 210 TRP A N   
2920 C CA  . TRP A 187 ? 0.22415 0.29596 0.28599 0.00591  -0.00128 -0.00704 210 TRP A CA  
2921 C C   . TRP A 187 ? 0.22473 0.28789 0.26648 0.01331  -0.01255 -0.01238 210 TRP A C   
2922 O O   . TRP A 187 ? 0.19021 0.26343 0.22132 0.03198  -0.01665 -0.01051 210 TRP A O   
2923 C CB  . TRP A 187 ? 0.21823 0.26214 0.26082 0.00562  0.01601  -0.00164 210 TRP A CB  
2924 C CG  . TRP A 187 ? 0.20089 0.25103 0.24945 0.01253  0.02992  0.00372  210 TRP A CG  
2925 C CD1 . TRP A 187 ? 0.22553 0.30521 0.29191 0.02612  0.03155  0.00765  210 TRP A CD1 
2926 C CD2 . TRP A 187 ? 0.18264 0.21122 0.21612 0.01025  0.04315  0.00384  210 TRP A CD2 
2927 N NE1 . TRP A 187 ? 0.23366 0.31000 0.29612 0.03407  0.04799  0.01160  210 TRP A NE1 
2928 C CE2 . TRP A 187 ? 0.20442 0.24670 0.24375 0.02446  0.05461  0.00819  210 TRP A CE2 
2929 C CE3 . TRP A 187 ? 0.27037 0.27315 0.28494 0.00028  0.04465  -0.00112 210 TRP A CE3 
2930 C CZ2 . TRP A 187 ? 0.26685 0.29141 0.28760 0.03018  0.06825  0.00668  210 TRP A CZ2 
2931 C CZ3 . TRP A 187 ? 0.28336 0.27177 0.28185 0.00388  0.05506  -0.00378 210 TRP A CZ3 
2932 C CH2 . TRP A 187 ? 0.23333 0.22929 0.23197 0.01918  0.06711  -0.00042 210 TRP A CH2 
2943 N N   . MET A 188 ? 0.20145 0.24698 0.23384 0.00340  -0.01651 -0.01783 211 MET A N   
2944 C CA  . MET A 188 ? 0.23474 0.27475 0.24531 0.01430  -0.02366 -0.02233 211 MET A CA  
2945 C C   . MET A 188 ? 0.23710 0.29474 0.24969 0.02300  -0.04454 -0.03424 211 MET A C   
2946 O O   . MET A 188 ? 0.23241 0.29524 0.22187 0.04284  -0.04900 -0.03517 211 MET A O   
2947 C CB  . MET A 188 ? 0.19979 0.22195 0.20132 0.00641  -0.02348 -0.02631 211 MET A CB  
2948 C CG  . MET A 188 ? 0.20739 0.21895 0.20527 0.00007  -0.00774 -0.01866 211 MET A CG  
2949 S SD  . MET A 188 ? 0.20040 0.20408 0.18967 -0.00280 -0.00938 -0.02308 211 MET A SD  
2950 C CE  . MET A 188 ? 0.19190 0.20655 0.16537 0.01492  -0.00926 -0.02327 211 MET A CE  
2960 N N   . LYS A 189 ? 0.24674 0.31439 0.28665 0.00818  -0.05759 -0.04370 212 LYS A N   
2961 C CA  . LYS A 189 ? 0.25213 0.33933 0.29976 0.01274  -0.08227 -0.06030 212 LYS A CA  
2962 C C   . LYS A 189 ? 0.22688 0.34880 0.27629 0.03307  -0.08656 -0.05708 212 LYS A C   
2963 O O   . LYS A 189 ? 0.21503 0.35572 0.25617 0.04760  -0.10822 -0.07091 212 LYS A O   
2964 C CB  . LYS A 189 ? 0.26446 0.35622 0.35160 -0.01410 -0.09352 -0.06982 212 LYS A CB  
2965 C CG  . LYS A 189 ? 0.36413 0.41407 0.44099 -0.02782 -0.09615 -0.07644 212 LYS A CG  
2966 C CD  . LYS A 189 ? 0.44664 0.48888 0.55895 -0.05713 -0.09565 -0.07529 212 LYS A CD  
2967 C CE  . LYS A 189 ? 0.53928 0.60477 0.67506 -0.06670 -0.11076 -0.08580 212 LYS A CE  
2968 N NZ  . LYS A 189 ? 0.72928 0.78802 0.89716 -0.09710 -0.10261 -0.07885 212 LYS A NZ  
2982 N N   . GLY A 190 ? 0.18891 0.33607 0.26538 0.00227  0.00929  -0.00779 213 GLY A N   
2983 C CA  . GLY A 190 ? 0.19418 0.35453 0.28244 0.01193  0.00457  -0.01109 213 GLY A CA  
2984 C C   . GLY A 190 ? 0.18469 0.32683 0.26447 0.02220  -0.00059 -0.01136 213 GLY A C   
2985 O O   . GLY A 190 ? 0.22795 0.37704 0.31492 0.03233  -0.00432 -0.01382 213 GLY A O   
2989 N N   . ASN A 191 ? 0.22124 0.34048 0.28590 0.02013  -0.00072 -0.00897 214 ASN A N   
2990 C CA  . ASN A 191 ? 0.17127 0.27332 0.22762 0.02771  -0.00505 -0.00874 214 ASN A CA  
2991 C C   . ASN A 191 ? 0.27531 0.37970 0.33547 0.03075  -0.01316 -0.00786 214 ASN A C   
2992 O O   . ASN A 191 ? 0.22582 0.33550 0.28825 0.02395  -0.01643 -0.00665 214 ASN A O   
2993 C CB  . ASN A 191 ? 0.24993 0.33127 0.29139 0.02292  -0.00444 -0.00635 214 ASN A CB  
2994 C CG  . ASN A 191 ? 0.20093 0.26591 0.23405 0.02854  -0.00803 -0.00577 214 ASN A CG  
2995 O OD1 . ASN A 191 ? 0.20339 0.26707 0.23866 0.03676  -0.00888 -0.00744 214 ASN A OD1 
2996 N ND2 . ASN A 191 ? 0.20981 0.26173 0.23294 0.02411  -0.01010 -0.00349 214 ASN A ND2 
3003 N N   . THR A 192 ? 0.23504 0.33316 0.29404 0.04093  -0.01690 -0.00839 215 THR A N   
3004 C CA  . THR A 192 ? 0.27676 0.37453 0.33638 0.04523  -0.02525 -0.00677 215 THR A CA  
3005 C C   . THR A 192 ? 0.26904 0.34369 0.31285 0.04475  -0.02868 -0.00302 215 THR A C   
3006 O O   . THR A 192 ? 0.28462 0.35709 0.32577 0.04772  -0.03566 -0.00086 215 THR A O   
3007 C CB  . THR A 192 ? 0.23106 0.33688 0.29921 0.05802  -0.02838 -0.00913 215 THR A CB  
3008 O OG1 . THR A 192 ? 0.22914 0.31493 0.28755 0.06481  -0.02718 -0.00903 215 THR A OG1 
3009 C CG2 . THR A 192 ? 0.20671 0.33821 0.29135 0.05974  -0.02378 -0.01379 215 THR A CG2 
3017 N N   . THR A 193 ? 0.22105 0.27993 0.25430 0.04122  -0.02407 -0.00227 216 THR A N   
3018 C CA  . THR A 193 ? 0.27317 0.31195 0.29264 0.04143  -0.02609 0.00079  216 THR A CA  
3019 C C   . THR A 193 ? 0.25853 0.29079 0.26895 0.03271  -0.02567 0.00252  216 THR A C   
3020 O O   . THR A 193 ? 0.29511 0.31284 0.29423 0.03161  -0.02568 0.00461  216 THR A O   
3021 C CB  . THR A 193 ? 0.23970 0.26551 0.25391 0.04405  -0.02173 -0.00040 216 THR A CB  
3022 O OG1 . THR A 193 ? 0.27008 0.29669 0.28280 0.03774  -0.01577 -0.00221 216 THR A OG1 
3023 C CG2 . THR A 193 ? 0.25284 0.28338 0.27499 0.05346  -0.02159 -0.00347 216 THR A CG2 
3031 N N   . GLY A 194 ? 0.19868 0.24070 0.21337 0.02633  -0.02492 0.00142  217 GLY A N   
3032 C CA  . GLY A 194 ? 0.24182 0.27555 0.24731 0.01933  -0.02377 0.00193  217 GLY A CA  
3033 C C   . GLY A 194 ? 0.18731 0.22183 0.18920 0.01552  -0.02910 0.00254  217 GLY A C   
3034 O O   . GLY A 194 ? 0.20899 0.23655 0.20320 0.01043  -0.02825 0.00203  217 GLY A O   
3038 N N   . ALA A 195 ? 0.19137 0.23449 0.19834 0.01854  -0.03509 0.00301  218 ALA A N   
3039 C CA  . ALA A 195 ? 0.22395 0.27085 0.22908 0.01403  -0.04055 0.00231  218 ALA A CA  
3040 C C   . ALA A 195 ? 0.24329 0.27615 0.23269 0.01291  -0.04218 0.00360  218 ALA A C   
3041 O O   . ALA A 195 ? 0.22936 0.26122 0.21403 0.00775  -0.04467 0.00175  218 ALA A O   
3042 C CB  . ALA A 195 ? 0.21365 0.27437 0.22757 0.01855  -0.04746 0.00223  218 ALA A CB  
3048 N N   . ALA A 196 ? 0.23568 0.25764 0.21655 0.01712  -0.04053 0.00636  219 ALA A N   
3049 C CA  . ALA A 196 ? 0.21576 0.22672 0.18174 0.01575  -0.04107 0.00778  219 ALA A CA  
3050 C C   . ALA A 196 ? 0.23758 0.24117 0.19795 0.01180  -0.03492 0.00601  219 ALA A C   
3051 O O   . ALA A 196 ? 0.23552 0.23243 0.18447 0.01049  -0.03433 0.00623  219 ALA A O   
3052 C CB  . ALA A 196 ? 0.28316 0.28566 0.24152 0.02093  -0.04231 0.01233  219 ALA A CB  
3058 N N   . SER A 197 ? 0.21619 0.22192 0.18390 0.01033  -0.03042 0.00409  220 SER A N   
3059 C CA  . SER A 197 ? 0.21319 0.21244 0.17586 0.00837  -0.02520 0.00252  220 SER A CA  
3060 C C   . SER A 197 ? 0.21757 0.21666 0.17944 0.00427  -0.02526 -0.00048 220 SER A C   
3061 O O   . SER A 197 ? 0.24836 0.24653 0.20537 0.00220  -0.02918 -0.00184 220 SER A O   
3062 C CB  . SER A 197 ? 0.22994 0.22901 0.19810 0.01051  -0.02057 0.00269  220 SER A CB  
3063 O OG  . SER A 197 ? 0.25228 0.24660 0.21781 0.01371  -0.02075 0.00520  220 SER A OG  
3069 N N   . ILE A 198 ? 0.18910 0.18757 0.15425 0.00317  -0.02137 -0.00157 221 ILE A N   
3070 C CA  . ILE A 198 ? 0.20288 0.19725 0.16512 -0.00051 -0.02165 -0.00371 221 ILE A CA  
3071 C C   . ILE A 198 ? 0.27186 0.27042 0.23804 -0.00488 -0.02622 -0.00423 221 ILE A C   
3072 O O   . ILE A 198 ? 0.22272 0.21533 0.18283 -0.00792 -0.02911 -0.00660 221 ILE A O   
3073 C CB  . ILE A 198 ? 0.22442 0.21766 0.18923 -0.00085 -0.01723 -0.00350 221 ILE A CB  
3074 C CG1 . ILE A 198 ? 0.23657 0.22491 0.19551 0.00278  -0.01408 -0.00462 221 ILE A CG1 
3075 C CG2 . ILE A 198 ? 0.19493 0.18294 0.15756 -0.00547 -0.01804 -0.00420 221 ILE A CG2 
3076 C CD1 . ILE A 198 ? 0.20976 0.19860 0.17091 0.00382  -0.01015 -0.00427 221 ILE A CD1 
3088 N N   . GLN A 199 ? 0.21299 0.22251 0.18976 -0.00510 -0.02721 -0.00275 222 GLN A N   
3089 C CA  . GLN A 199 ? 0.19766 0.21497 0.18084 -0.01002 -0.03162 -0.00375 222 GLN A CA  
3090 C C   . GLN A 199 ? 0.23404 0.24897 0.21028 -0.01041 -0.03792 -0.00552 222 GLN A C   
3091 O O   . GLN A 199 ? 0.24009 0.25664 0.21754 -0.01606 -0.04202 -0.00792 222 GLN A O   
3092 C CB  . GLN A 199 ? 0.23058 0.26356 0.22722 -0.00799 -0.03220 -0.00251 222 GLN A CB  
3093 C CG  . GLN A 199 ? 0.26087 0.30091 0.26640 -0.00866 -0.02634 -0.00167 222 GLN A CG  
3094 C CD  . GLN A 199 ? 0.35901 0.41535 0.37742 -0.00382 -0.02706 -0.00147 222 GLN A CD  
3095 O OE1 . GLN A 199 ? 0.32388 0.39117 0.34917 -0.00381 -0.03246 -0.00232 222 GLN A OE1 
3096 N NE2 . GLN A 199 ? 0.27936 0.33750 0.30074 0.00107  -0.02207 -0.00099 222 GLN A NE2 
3105 N N   . ALA A 200 ? 0.24647 0.25808 0.21520 -0.00506 -0.03890 -0.00437 223 ALA A N   
3106 C CA  . ALA A 200 ? 0.21546 0.22586 0.17593 -0.00492 -0.04481 -0.00572 223 ALA A CA  
3107 C C   . ALA A 200 ? 0.24625 0.24600 0.19539 -0.00769 -0.04504 -0.00961 223 ALA A C   
3108 O O   . ALA A 200 ? 0.28029 0.27918 0.22233 -0.00868 -0.05029 -0.01219 223 ALA A O   
3109 C CB  . ALA A 200 ? 0.21756 0.22620 0.17116 0.00101  -0.04510 -0.00236 223 ALA A CB  
3115 N N   . GLY A 201 ? 0.24684 0.23844 0.19337 -0.00797 -0.03995 -0.01052 224 GLY A N   
3116 C CA  . GLY A 201 ? 0.24607 0.22669 0.18259 -0.00917 -0.04028 -0.01480 224 GLY A CA  
3117 C C   . GLY A 201 ? 0.29383 0.26826 0.23267 -0.01503 -0.04152 -0.01696 224 GLY A C   
3118 O O   . GLY A 201 ? 0.29666 0.25885 0.22641 -0.01506 -0.04192 -0.02061 224 GLY A O   
3122 N N   . LEU A 202 ? 0.24209 0.22435 0.19242 -0.02014 -0.04219 -0.01498 225 LEU A N   
3123 C CA  . LEU A 202 ? 0.25157 0.22806 0.20433 -0.02770 -0.04257 -0.01591 225 LEU A CA  
3124 C C   . LEU A 202 ? 0.30278 0.28782 0.26236 -0.03482 -0.04857 -0.01798 225 LEU A C   
3125 O O   . LEU A 202 ? 0.25490 0.25421 0.22095 -0.03272 -0.05163 -0.01740 225 LEU A O   
3126 C CB  . LEU A 202 ? 0.25700 0.23748 0.21803 -0.02899 -0.03662 -0.01163 225 LEU A CB  
3127 C CG  . LEU A 202 ? 0.25637 0.23233 0.21335 -0.02231 -0.03106 -0.00958 225 LEU A CG  
3128 C CD1 . LEU A 202 ? 0.26384 0.24633 0.22918 -0.02425 -0.02598 -0.00583 225 LEU A CD1 
3129 C CD2 . LEU A 202 ? 0.27431 0.23337 0.21891 -0.02042 -0.03083 -0.01179 225 LEU A CD2 
3141 N N   . PRO A 203 ? 0.27218 0.24831 0.23006 -0.04327 -0.05096 -0.02060 226 PRO A N   
3142 C CA  . PRO A 203 ? 0.26377 0.25043 0.23040 -0.05177 -0.05667 -0.02304 226 PRO A CA  
3143 C C   . PRO A 203 ? 0.28582 0.29512 0.27005 -0.05309 -0.05473 -0.01947 226 PRO A C   
3144 O O   . PRO A 203 ? 0.24268 0.25542 0.23219 -0.05146 -0.04813 -0.01528 226 PRO A O   
3145 C CB  . PRO A 203 ? 0.28010 0.25074 0.24268 -0.06204 -0.05710 -0.02489 226 PRO A CB  
3146 C CG  . PRO A 203 ? 0.28646 0.23469 0.23291 -0.05561 -0.05471 -0.02566 226 PRO A CG  
3147 C CD  . PRO A 203 ? 0.30668 0.26179 0.25406 -0.04535 -0.04911 -0.02163 226 PRO A CD  
3155 N N   . ALA A 204 ? 0.25210 0.27782 0.24519 -0.05526 -0.06096 -0.02178 227 ALA A N   
3156 C CA  . ALA A 204 ? 0.24248 0.29215 0.25352 -0.05534 -0.06006 -0.01960 227 ALA A CA  
3157 C C   . ALA A 204 ? 0.24805 0.30356 0.27005 -0.06556 -0.05471 -0.01796 227 ALA A C   
3158 O O   . ALA A 204 ? 0.25249 0.32536 0.28750 -0.06382 -0.05039 -0.01536 227 ALA A O   
3159 C CB  . ALA A 204 ? 0.27565 0.34219 0.29402 -0.05629 -0.06917 -0.02331 227 ALA A CB  
3165 N N   . SER A 205 ? 0.27170 0.31247 0.28789 -0.07622 -0.05472 -0.01940 228 SER A N   
3166 C CA  . SER A 205 ? 0.32338 0.36962 0.34901 -0.08783 -0.04956 -0.01710 228 SER A CA  
3167 C C   . SER A 205 ? 0.30236 0.34128 0.32409 -0.08440 -0.04017 -0.01144 228 SER A C   
3168 O O   . SER A 205 ? 0.30374 0.35141 0.33385 -0.09238 -0.03443 -0.00848 228 SER A O   
3169 C CB  . SER A 205 ? 0.30069 0.32929 0.31926 -0.10127 -0.05260 -0.01977 228 SER A CB  
3170 O OG  . SER A 205 ? 0.35884 0.35729 0.35788 -0.09759 -0.05133 -0.01910 228 SER A OG  
3176 N N   . TRP A 206 ? 0.25005 0.27449 0.25928 -0.07338 -0.03840 -0.01009 229 TRP A N   
3177 C CA  . TRP A 206 ? 0.25860 0.27370 0.26186 -0.07040 -0.03067 -0.00550 229 TRP A CA  
3178 C C   . TRP A 206 ? 0.29035 0.32587 0.30518 -0.06396 -0.02559 -0.00311 229 TRP A C   
3179 O O   . TRP A 206 ? 0.27952 0.32762 0.30051 -0.05589 -0.02828 -0.00464 229 TRP A O   
3180 C CB  . TRP A 206 ? 0.26262 0.25614 0.24908 -0.06133 -0.03113 -0.00592 229 TRP A CB  
3181 C CG  . TRP A 206 ? 0.31676 0.28702 0.28966 -0.06567 -0.03520 -0.00861 229 TRP A CG  
3182 C CD1 . TRP A 206 ? 0.35697 0.32236 0.33040 -0.07665 -0.03983 -0.01144 229 TRP A CD1 
3183 C CD2 . TRP A 206 ? 0.27287 0.22150 0.22975 -0.05862 -0.03530 -0.00952 229 TRP A CD2 
3184 N NE1 . TRP A 206 ? 0.31229 0.25205 0.26989 -0.07638 -0.04284 -0.01408 229 TRP A NE1 
3185 C CE2 . TRP A 206 ? 0.32409 0.25411 0.27165 -0.06469 -0.04010 -0.01301 229 TRP A CE2 
3186 C CE3 . TRP A 206 ? 0.26468 0.20878 0.21487 -0.04780 -0.03196 -0.00825 229 TRP A CE3 
3187 C CZ2 . TRP A 206 ? 0.34775 0.25481 0.27930 -0.05876 -0.04168 -0.01545 229 TRP A CZ2 
3188 C CZ3 . TRP A 206 ? 0.28635 0.21032 0.22199 -0.04256 -0.03348 -0.01059 229 TRP A CZ3 
3189 C CH2 . TRP A 206 ? 0.32907 0.23474 0.25543 -0.04729 -0.03824 -0.01417 229 TRP A CH2 
3200 N N   . VAL A 207 ? 0.30042 0.33736 0.31643 -0.06710 -0.01830 0.00067  230 VAL A N   
3201 C CA  . VAL A 207 ? 0.24601 0.30120 0.27178 -0.06123 -0.01275 0.00220  230 VAL A CA  
3202 C C   . VAL A 207 ? 0.30816 0.35071 0.32273 -0.05051 -0.00984 0.00361  230 VAL A C   
3203 O O   . VAL A 207 ? 0.28815 0.31090 0.28894 -0.05098 -0.00847 0.00540  230 VAL A O   
3204 C CB  . VAL A 207 ? 0.30348 0.36982 0.33645 -0.07111 -0.00587 0.00511  230 VAL A CB  
3205 C CG1 . VAL A 207 ? 0.27527 0.36127 0.31773 -0.06387 0.00007  0.00553  230 VAL A CG1 
3206 C CG2 . VAL A 207 ? 0.37626 0.45676 0.42170 -0.08318 -0.00890 0.00314  230 VAL A CG2 
3216 N N   . VAL A 208 ? 0.22298 0.27640 0.24330 -0.04063 -0.00963 0.00243  231 VAL A N   
3217 C CA  . VAL A 208 ? 0.23076 0.27403 0.24214 -0.03106 -0.00771 0.00281  231 VAL A CA  
3218 C C   . VAL A 208 ? 0.27122 0.32887 0.29071 -0.02518 -0.00283 0.00283  231 VAL A C   
3219 O O   . VAL A 208 ? 0.21237 0.28794 0.24481 -0.02342 -0.00364 0.00132  231 VAL A O   
3220 C CB  . VAL A 208 ? 0.29702 0.33352 0.30366 -0.02454 -0.01339 0.00078  231 VAL A CB  
3221 C CG1 . VAL A 208 ? 0.27834 0.30764 0.27831 -0.01601 -0.01100 0.00091  231 VAL A CG1 
3222 C CG2 . VAL A 208 ? 0.33708 0.35928 0.33440 -0.02944 -0.01800 -0.00038 231 VAL A CG2 
3232 N N   . GLY A 209 ? 0.18799 0.23789 0.19956 -0.02130 0.00164  0.00386  232 GLY A N   
3233 C CA  . GLY A 209 ? 0.23095 0.28979 0.24667 -0.01390 0.00553  0.00265  232 GLY A CA  
3234 C C   . GLY A 209 ? 0.21656 0.26146 0.22264 -0.00683 0.00402  0.00163  232 GLY A C   
3235 O O   . GLY A 209 ? 0.22557 0.25724 0.22057 -0.00776 0.00472  0.00267  232 GLY A O   
3239 N N   . ASP A 210 ? 0.17942 0.22673 0.18931 -0.00003 0.00161  -0.00030 233 ASP A N   
3240 C CA  . ASP A 210 ? 0.18915 0.22403 0.19070 0.00467  0.00019  -0.00114 233 ASP A CA  
3241 C C   . ASP A 210 ? 0.17544 0.21334 0.18061 0.01183  0.00125  -0.00320 233 ASP A C   
3242 O O   . ASP A 210 ? 0.20332 0.25263 0.21787 0.01490  0.00161  -0.00425 233 ASP A O   
3243 C CB  . ASP A 210 ? 0.17300 0.20088 0.17095 0.00391  -0.00526 -0.00073 233 ASP A CB  
3244 C CG  . ASP A 210 ? 0.19383 0.22723 0.19786 0.00811  -0.00892 -0.00092 233 ASP A CG  
3245 O OD1 . ASP A 210 ? 0.20945 0.25529 0.22316 0.00745  -0.01041 -0.00102 233 ASP A OD1 
3246 O OD2 . ASP A 210 ? 0.20514 0.23080 0.20424 0.01206  -0.01043 -0.00083 233 ASP A OD2 
3251 N N   . LYS A 211 ? 0.23329 0.26078 0.23108 0.01452  0.00149  -0.00425 234 LYS A N   
3252 C CA  . LYS A 211 ? 0.19174 0.21670 0.19057 0.02026  0.00149  -0.00632 234 LYS A CA  
3253 C C   . LYS A 211 ? 0.17647 0.19009 0.16864 0.01999  -0.00126 -0.00562 234 LYS A C   
3254 O O   . LYS A 211 ? 0.17693 0.18492 0.16247 0.01769  -0.00034 -0.00609 234 LYS A O   
3255 C CB  . LYS A 211 ? 0.19914 0.22406 0.19566 0.02253  0.00562  -0.00924 234 LYS A CB  
3256 C CG  . LYS A 211 ? 0.21915 0.23867 0.21603 0.02784  0.00511  -0.01219 234 LYS A CG  
3257 C CD  . LYS A 211 ? 0.23820 0.26519 0.24357 0.03346  0.00477  -0.01355 234 LYS A CD  
3258 C CE  . LYS A 211 ? 0.23923 0.25538 0.24353 0.03871  0.00204  -0.01504 234 LYS A CE  
3259 N NZ  . LYS A 211 ? 0.24198 0.25042 0.24448 0.03835  -0.00275 -0.01117 234 LYS A NZ  
3273 N N   . THR A 212 ? 0.21124 0.22219 0.20487 0.02265  -0.00449 -0.00447 235 THR A N   
3274 C CA  . THR A 212 ? 0.20028 0.20060 0.18657 0.02157  -0.00623 -0.00313 235 THR A CA  
3275 C C   . THR A 212 ? 0.21838 0.21090 0.20210 0.02315  -0.00427 -0.00516 235 THR A C   
3276 O O   . THR A 212 ? 0.21217 0.20635 0.19962 0.02661  -0.00251 -0.00798 235 THR A O   
3277 C CB  . THR A 212 ? 0.23106 0.22981 0.21740 0.02347  -0.01089 -0.00009 235 THR A CB  
3278 O OG1 . THR A 212 ? 0.25799 0.25898 0.25061 0.02960  -0.01205 -0.00070 235 THR A OG1 
3279 C CG2 . THR A 212 ? 0.21808 0.22477 0.20672 0.02072  -0.01339 0.00092  235 THR A CG2 
3287 N N   . GLY A 213 ? 0.20254 0.18698 0.17967 0.02011  -0.00445 -0.00413 236 GLY A N   
3288 C CA  . GLY A 213 ? 0.20026 0.17569 0.17477 0.01983  -0.00326 -0.00555 236 GLY A CA  
3289 C C   . GLY A 213 ? 0.27304 0.23953 0.24060 0.01637  -0.00441 -0.00195 236 GLY A C   
3290 O O   . GLY A 213 ? 0.22991 0.19913 0.19368 0.01343  -0.00481 0.00003  236 GLY A O   
3294 N N   . SER A 214 ? 0.23620 0.19096 0.20100 0.01665  -0.00485 -0.00111 237 SER A N   
3295 C CA  . SER A 214 ? 0.36000 0.30497 0.31653 0.01160  -0.00478 0.00282  237 SER A CA  
3296 C C   . SER A 214 ? 0.25141 0.18337 0.20560 0.00907  -0.00350 0.00157  237 SER A C   
3297 O O   . SER A 214 ? 0.29378 0.22124 0.25162 0.01351  -0.00422 -0.00169 237 SER A O   
3298 C CB  . SER A 214 ? 0.34551 0.28545 0.29697 0.01428  -0.00880 0.00876  237 SER A CB  
3299 O OG  . SER A 214 ? 0.43315 0.36880 0.38808 0.02180  -0.01231 0.00919  237 SER A OG  
3305 N N   . GLY A 215 ? 0.33778 0.26401 0.28568 0.00134  -0.00132 0.00369  238 GLY A N   
3306 C CA  . GLY A 215 ? 0.25959 0.17245 0.20501 -0.00332 -0.00000 0.00246  238 GLY A CA  
3307 C C   . GLY A 215 ? 0.31545 0.22251 0.25322 -0.01327 0.00280  0.00643  238 GLY A C   
3308 O O   . GLY A 215 ? 0.28350 0.19102 0.21467 -0.01441 0.00262  0.01210  238 GLY A O   
3312 N N   . GLY A 216 ? 0.30617 0.20801 0.24435 -0.02094 0.00544  0.00337  239 GLY A N   
3313 C CA  . GLY A 216 ? 0.29614 0.19319 0.22769 -0.03220 0.00903  0.00713  239 GLY A CA  
3314 C C   . GLY A 216 ? 0.27651 0.19373 0.20943 -0.03598 0.01260  0.00683  239 GLY A C   
3315 O O   . GLY A 216 ? 0.25798 0.19176 0.19757 -0.03077 0.01225  0.00256  239 GLY A O   
3319 N N   . TYR A 217 ? 0.28914 0.20388 0.21452 -0.04518 0.01627  0.01163  240 TYR A N   
3320 C CA  . TYR A 217 ? 0.30894 0.24256 0.23415 -0.04852 0.02019  0.01128  240 TYR A CA  
3321 C C   . TYR A 217 ? 0.27072 0.21165 0.19439 -0.03885 0.01713  0.01245  240 TYR A C   
3322 O O   . TYR A 217 ? 0.28295 0.24135 0.21083 -0.03677 0.01846  0.00832  240 TYR A O   
3323 C CB  . TYR A 217 ? 0.28782 0.24112 0.22442 -0.05259 0.02346  0.00270  240 TYR A CB  
3324 C CG  . TYR A 217 ? 0.28773 0.23731 0.22512 -0.06563 0.02747  0.00191  240 TYR A CG  
3325 C CD1 . TYR A 217 ? 0.29133 0.22636 0.23104 -0.06792 0.02538  -0.00046 240 TYR A CD1 
3326 C CD2 . TYR A 217 ? 0.30260 0.26313 0.23808 -0.07609 0.03350  0.00328  240 TYR A CD2 
3327 C CE1 . TYR A 217 ? 0.31286 0.24285 0.25310 -0.08096 0.02860  -0.00151 240 TYR A CE1 
3328 C CE2 . TYR A 217 ? 0.30851 0.26595 0.24516 -0.08992 0.03752  0.00284  240 TYR A CE2 
3329 C CZ  . TYR A 217 ? 0.35769 0.29926 0.29683 -0.09265 0.03478  0.00039  240 TYR A CZ  
3330 O OH  . TYR A 217 ? 0.39557 0.33284 0.33594 -0.10764 0.03840  -0.00057 240 TYR A OH  
3340 N N   . GLY A 218 ? 0.29039 0.21741 0.20767 -0.03293 0.01262  0.01794  241 GLY A N   
3341 C CA  . GLY A 218 ? 0.30086 0.23384 0.21650 -0.02500 0.00904  0.01918  241 GLY A CA  
3342 C C   . GLY A 218 ? 0.29356 0.24134 0.22000 -0.01911 0.00794  0.01225  241 GLY A C   
3343 O O   . GLY A 218 ? 0.26526 0.22241 0.19108 -0.01580 0.00690  0.01130  241 GLY A O   
3347 N N   . THR A 219 ? 0.25076 0.19962 0.18595 -0.01808 0.00810  0.00729  242 THR A N   
3348 C CA  . THR A 219 ? 0.27974 0.24077 0.22329 -0.01277 0.00719  0.00162  242 THR A CA  
3349 C C   . THR A 219 ? 0.26795 0.22710 0.21216 -0.00537 0.00283  0.00364  242 THR A C   
3350 O O   . THR A 219 ? 0.24992 0.19913 0.19361 -0.00220 0.00013  0.00639  242 THR A O   
3351 C CB  . THR A 219 ? 0.27807 0.23983 0.22879 -0.01324 0.00806  -0.00374 242 THR A CB  
3352 O OG1 . THR A 219 ? 0.25800 0.22523 0.20967 -0.02105 0.01186  -0.00649 242 THR A OG1 
3353 C CG2 . THR A 219 ? 0.22587 0.19790 0.18293 -0.00719 0.00684  -0.00833 242 THR A CG2 
3361 N N   . THR A 220 ? 0.23215 0.20094 0.17751 -0.00271 0.00195  0.00205  243 THR A N   
3362 C CA  . THR A 220 ? 0.24043 0.21001 0.18702 0.00241  -0.00203 0.00357  243 THR A CA  
3363 C C   . THR A 220 ? 0.21871 0.19733 0.17049 0.00455  -0.00181 -0.00071 243 THR A C   
3364 O O   . THR A 220 ? 0.21510 0.19909 0.16459 0.00333  -0.00046 -0.00304 243 THR A O   
3365 C CB  . THR A 220 ? 0.29168 0.26007 0.23010 0.00175  -0.00411 0.00737  243 THR A CB  
3366 O OG1 . THR A 220 ? 0.26670 0.22614 0.19720 -0.00178 -0.00305 0.01188  243 THR A OG1 
3367 C CG2 . THR A 220 ? 0.25664 0.22517 0.19716 0.00635  -0.00912 0.00917  243 THR A CG2 
3375 N N   . ASN A 221 ? 0.21467 0.19462 0.17276 0.00798  -0.00289 -0.00180 244 ASN A N   
3376 C CA  . ASN A 221 ? 0.24434 0.23040 0.20600 0.00935  -0.00198 -0.00511 244 ASN A CA  
3377 C C   . ASN A 221 ? 0.21095 0.19976 0.17661 0.01158  -0.00412 -0.00394 244 ASN A C   
3378 O O   . ASN A 221 ? 0.20843 0.19651 0.17709 0.01341  -0.00602 -0.00187 244 ASN A O   
3379 C CB  . ASN A 221 ? 0.18220 0.16896 0.14744 0.01009  0.00031  -0.00832 244 ASN A CB  
3380 C CG  . ASN A 221 ? 0.23090 0.21765 0.19437 0.00677  0.00248  -0.01066 244 ASN A CG  
3381 O OD1 . ASN A 221 ? 0.22027 0.20985 0.18043 0.00436  0.00327  -0.01083 244 ASN A OD1 
3382 N ND2 . ASN A 221 ? 0.21098 0.19594 0.17708 0.00652  0.00357  -0.01329 244 ASN A ND2 
3389 N N   . ASP A 222 ? 0.21387 0.20594 0.17967 0.01140  -0.00387 -0.00530 245 ASP A N   
3390 C CA  . ASP A 222 ? 0.19882 0.19459 0.16912 0.01167  -0.00480 -0.00432 245 ASP A CA  
3391 C C   . ASP A 222 ? 0.19624 0.19237 0.16458 0.01119  -0.00307 -0.00570 245 ASP A C   
3392 O O   . ASP A 222 ? 0.20378 0.19675 0.16652 0.01112  -0.00320 -0.00709 245 ASP A O   
3393 C CB  . ASP A 222 ? 0.19722 0.19347 0.16696 0.00998  -0.00851 -0.00248 245 ASP A CB  
3394 C CG  . ASP A 222 ? 0.20956 0.21263 0.18692 0.00952  -0.00979 -0.00146 245 ASP A CG  
3395 O OD1 . ASP A 222 ? 0.18589 0.19407 0.16936 0.01128  -0.00745 -0.00183 245 ASP A OD1 
3396 O OD2 . ASP A 222 ? 0.17797 0.18260 0.15541 0.00716  -0.01321 -0.00081 245 ASP A OD2 
3401 N N   . ILE A 223 ? 0.17605 0.17618 0.14837 0.01139  -0.00142 -0.00526 246 ILE A N   
3402 C CA  . ILE A 223 ? 0.17304 0.17201 0.14169 0.01056  0.00017  -0.00517 246 ILE A CA  
3403 C C   . ILE A 223 ? 0.17930 0.18253 0.15218 0.00722  0.00059  -0.00283 246 ILE A C   
3404 O O   . ILE A 223 ? 0.19823 0.20957 0.17895 0.00773  0.00137  -0.00261 246 ILE A O   
3405 C CB  . ILE A 223 ? 0.21587 0.21639 0.18303 0.01343  0.00297  -0.00712 246 ILE A CB  
3406 C CG1 . ILE A 223 ? 0.19536 0.20267 0.16844 0.01487  0.00553  -0.00761 246 ILE A CG1 
3407 C CG2 . ILE A 223 ? 0.20669 0.20542 0.17193 0.01536  0.00245  -0.01007 246 ILE A CG2 
3408 C CD1 . ILE A 223 ? 0.19793 0.20649 0.16788 0.01784  0.00793  -0.01052 246 ILE A CD1 
3420 N N   . ALA A 224 ? 0.19413 0.19204 0.16203 0.00377  0.00006  -0.00131 247 ALA A N   
3421 C CA  . ALA A 224 ? 0.18435 0.18629 0.15683 -0.00165 0.00007  0.00085  247 ALA A CA  
3422 C C   . ALA A 224 ? 0.20191 0.19682 0.16746 -0.00573 0.00175  0.00332  247 ALA A C   
3423 O O   . ALA A 224 ? 0.22872 0.21172 0.18426 -0.00417 0.00049  0.00329  247 ALA A O   
3424 C CB  . ALA A 224 ? 0.19881 0.19925 0.17282 -0.00435 -0.00453 0.00044  247 ALA A CB  
3430 N N   . VAL A 225 ? 0.20235 0.20466 0.17317 -0.01111 0.00440  0.00557  248 VAL A N   
3431 C CA  . VAL A 225 ? 0.22940 0.22395 0.19411 -0.01811 0.00560  0.00903  248 VAL A CA  
3432 C C   . VAL A 225 ? 0.26341 0.25991 0.23432 -0.02546 0.00244  0.00895  248 VAL A C   
3433 O O   . VAL A 225 ? 0.21576 0.22744 0.19889 -0.02626 0.00199  0.00756  248 VAL A O   
3434 C CB  . VAL A 225 ? 0.25576 0.25811 0.22089 -0.02050 0.01178  0.01186  248 VAL A CB  
3435 C CG1 . VAL A 225 ? 0.31628 0.33952 0.29630 -0.02113 0.01452  0.01038  248 VAL A CG1 
3436 C CG2 . VAL A 225 ? 0.28862 0.28085 0.24604 -0.02944 0.01323  0.01660  248 VAL A CG2 
3446 N N   . ILE A 226 ? 0.22643 0.20723 0.18863 -0.03012 -0.00045 0.00988  249 ILE A N   
3447 C CA  . ILE A 226 ? 0.26965 0.24939 0.23565 -0.03671 -0.00491 0.00839  249 ILE A CA  
3448 C C   . ILE A 226 ? 0.31833 0.28777 0.27951 -0.04740 -0.00406 0.01160  249 ILE A C   
3449 O O   . ILE A 226 ? 0.27107 0.22171 0.21865 -0.04720 -0.00364 0.01403  249 ILE A O   
3450 C CB  . ILE A 226 ? 0.25128 0.21923 0.21002 -0.03177 -0.01049 0.00472  249 ILE A CB  
3451 C CG1 . ILE A 226 ? 0.21628 0.19287 0.17843 -0.02278 -0.01083 0.00235  249 ILE A CG1 
3452 C CG2 . ILE A 226 ? 0.31442 0.28143 0.27603 -0.03856 -0.01576 0.00230  249 ILE A CG2 
3453 C CD1 . ILE A 226 ? 0.27750 0.24260 0.23002 -0.01716 -0.01404 -0.00068 249 ILE A CD1 
3465 N N   . TRP A 227 ? 0.24886 0.23071 0.22118 -0.05684 -0.00403 0.01168  250 TRP A N   
3466 C CA  . TRP A 227 ? 0.27585 0.24877 0.24539 -0.06974 -0.00377 0.01423  250 TRP A CA  
3467 C C   . TRP A 227 ? 0.34926 0.31611 0.31979 -0.07452 -0.01102 0.00996  250 TRP A C   
3468 O O   . TRP A 227 ? 0.30918 0.29441 0.29362 -0.07909 -0.01320 0.00734  250 TRP A O   
3469 C CB  . TRP A 227 ? 0.32089 0.31516 0.30345 -0.07857 0.00213  0.01688  250 TRP A CB  
3470 C CG  . TRP A 227 ? 0.45103 0.44886 0.42940 -0.07460 0.00961  0.02099  250 TRP A CG  
3471 C CD1 . TRP A 227 ? 0.42963 0.41279 0.39477 -0.07941 0.01406  0.02677  250 TRP A CD1 
3472 C CD2 . TRP A 227 ? 0.40061 0.41640 0.38636 -0.06467 0.01301  0.01940  250 TRP A CD2 
3473 N NE1 . TRP A 227 ? 0.42791 0.42116 0.39207 -0.07319 0.02014  0.02862  250 TRP A NE1 
3474 C CE2 . TRP A 227 ? 0.39262 0.40554 0.36966 -0.06418 0.01954  0.02367  250 TRP A CE2 
3475 C CE3 . TRP A 227 ? 0.41602 0.44844 0.41373 -0.05615 0.01083  0.01485  250 TRP A CE3 
3476 C CZ2 . TRP A 227 ? 0.40503 0.43185 0.38550 -0.05556 0.02384  0.02243  250 TRP A CZ2 
3477 C CZ3 . TRP A 227 ? 0.46554 0.50967 0.46662 -0.04780 0.01506  0.01407  250 TRP A CZ3 
3478 C CH2 . TRP A 227 ? 0.47641 0.51815 0.46923 -0.04756 0.02150  0.01732  250 TRP A CH2 
3489 N N   . PRO A 228 ? 0.31699 0.30473 0.21704 -0.04391 -0.08949 0.00336  251 PRO A N   
3490 C CA  . PRO A 228 ? 0.46910 0.41612 0.31225 -0.06815 -0.08762 0.00565  251 PRO A CA  
3491 C C   . PRO A 228 ? 0.45627 0.39453 0.28446 -0.08658 -0.09460 0.01957  251 PRO A C   
3492 O O   . PRO A 228 ? 0.43477 0.39118 0.29250 -0.07660 -0.09965 0.02207  251 PRO A O   
3493 C CB  . PRO A 228 ? 0.44489 0.33799 0.24772 -0.07747 -0.07893 -0.01323 251 PRO A CB  
3494 C CG  . PRO A 228 ? 0.44729 0.36411 0.29963 -0.05571 -0.08392 -0.02190 251 PRO A CG  
3495 C CD  . PRO A 228 ? 0.30370 0.29719 0.22526 -0.03388 -0.08528 -0.01136 251 PRO A CD  
3503 N N   . LYS A 229 ? 0.50367 0.41491 0.28521 -0.11954 -0.09351 0.02948  252 LYS A N   
3504 C CA  . LYS A 229 ? 0.46911 0.37124 0.23295 -0.14540 -0.10002 0.04301  252 LYS A CA  
3505 C C   . LYS A 229 ? 0.51585 0.39106 0.26517 -0.13888 -0.09644 0.03044  252 LYS A C   
3506 O O   . LYS A 229 ? 0.57125 0.40683 0.28403 -0.14073 -0.08176 0.01261  252 LYS A O   
3507 C CB  . LYS A 229 ? 0.59875 0.47544 0.31138 -0.19392 -0.09787 0.05408  252 LYS A CB  
3508 C CG  . LYS A 229 ? 0.67754 0.55325 0.37674 -0.22828 -0.10713 0.07059  252 LYS A CG  
3509 C CD  . LYS A 229 ? 0.73445 0.58559 0.38046 -0.28955 -0.10560 0.07951  252 LYS A CD  
3510 C CE  . LYS A 229 ? 0.90368 0.76107 0.53909 -0.32120 -0.11595 0.09349  252 LYS A CE  
3511 N NZ  . LYS A 229 ? 1.14941 0.99559 0.73563 -0.36696 -0.11421 0.09424  252 LYS A NZ  
3525 N N   . ASP A 230 ? 0.51694 0.41424 0.29746 -0.13057 -0.10616 0.03812  253 ASP A N   
3526 C CA  . ASP A 230 ? 0.54561 0.42678 0.32191 -0.12515 -0.10704 0.03112  253 ASP A CA  
3527 C C   . ASP A 230 ? 0.60968 0.48753 0.40000 -0.10103 -0.10024 0.00971  253 ASP A C   
3528 O O   . ASP A 230 ? 0.54023 0.37924 0.29978 -0.10829 -0.09379 -0.00276 253 ASP A O   
3529 C CB  . ASP A 230 ? 0.80427 0.63413 0.51428 -0.16304 -0.10264 0.03525  253 ASP A CB  
3530 C CG  . ASP A 230 ? 0.74574 0.58971 0.45561 -0.19198 -0.11362 0.05735  253 ASP A CG  
3531 O OD1 . ASP A 230 ? 0.86692 0.74819 0.62272 -0.17716 -0.12291 0.06599  253 ASP A OD1 
3532 O OD2 . ASP A 230 ? 0.84058 0.65945 0.50420 -0.23444 -0.11071 0.06538  253 ASP A OD2 
3537 N N   . ARG A 231 ? 0.46115 0.37579 0.29866 -0.07777 -0.10024 0.00424  254 ARG A N   
3538 C CA  A ARG A 231 ? 0.51418 0.42226 0.37115 -0.06819 -0.10047 -0.01052 254 ARG A CA  
3539 C CA  B ARG A 231 ? 0.51467 0.42201 0.37067 -0.06835 -0.10021 -0.01074 254 ARG A CA  
3540 C C   . ARG A 231 ? 0.33770 0.31716 0.27349 -0.04282 -0.09940 -0.00556 254 ARG A C   
3541 O O   . ARG A 231 ? 0.33287 0.33075 0.27932 -0.03930 -0.09904 0.00386  254 ARG A O   
3542 C CB  A ARG A 231 ? 0.56377 0.39734 0.36137 -0.08416 -0.08512 -0.02848 254 ARG A CB  
3543 C CB  B ARG A 231 ? 0.56080 0.40016 0.36190 -0.08260 -0.08576 -0.02765 254 ARG A CB  
3544 C CG  A ARG A 231 ? 0.65788 0.39614 0.37658 -0.10991 -0.04997 -0.04491 254 ARG A CG  
3545 C CG  B ARG A 231 ? 0.65303 0.40480 0.36736 -0.11091 -0.05278 -0.04081 254 ARG A CG  
3546 C CD  A ARG A 231 ? 0.76384 0.46666 0.43196 -0.12508 -0.02062 -0.05173 254 ARG A CD  
3547 C CD  B ARG A 231 ? 0.69561 0.39532 0.39104 -0.11106 -0.01218 -0.05995 254 ARG A CD  
3548 N NE  A ARG A 231 ? 0.78023 0.52641 0.43444 -0.14132 -0.04279 -0.02689 254 ARG A NE  
3549 N NE  B ARG A 231 ? 0.82722 0.46164 0.45617 -0.13672 0.02954  -0.06939 254 ARG A NE  
3550 C CZ  A ARG A 231 ? 0.65025 0.36620 0.25279 -0.17277 -0.02620 -0.02357 254 ARG A CZ  
3551 C CZ  B ARG A 231 ? 0.91757 0.49287 0.54792 -0.13284 0.07632  -0.08453 254 ARG A CZ  
3552 N NH1 A ARG A 231 ? 0.81645 0.46483 0.36725 -0.18992 0.01581  -0.04375 254 ARG A NH1 
3553 N NH1 B ARG A 231 ? 0.79679 0.36993 0.50529 -0.10128 0.08881  -0.08494 254 ARG A NH1 
3554 N NH2 A ARG A 231 ? 0.72522 0.48367 0.34285 -0.18670 -0.04634 -0.00088 254 ARG A NH2 
3555 N NH2 B ARG A 231 ? 1.00582 0.52818 0.56836 -0.16268 0.11448  -0.09245 254 ARG A NH2 
3582 N N   . ALA A 232 ? 0.31694 0.30371 0.29540 -0.03872 -0.10664 -0.00450 255 ALA A N   
3583 C CA  . ALA A 232 ? 0.23083 0.27218 0.26326 -0.02349 -0.09257 0.00177  255 ALA A CA  
3584 C C   . ALA A 232 ? 0.24579 0.29619 0.27714 -0.01918 -0.08510 -0.00353 255 ALA A C   
3585 O O   . ALA A 232 ? 0.28059 0.28783 0.28845 -0.02625 -0.09943 -0.01047 255 ALA A O   
3586 C CB  . ALA A 232 ? 0.20595 0.26514 0.29719 -0.01923 -0.09084 0.01262  255 ALA A CB  
3592 N N   . PRO A 233 ? 0.28224 0.35336 0.32840 -0.01524 -0.07848 -0.00061 256 PRO A N   
3593 C CA  . PRO A 233 ? 0.18656 0.26499 0.22966 -0.01238 -0.07212 -0.00512 256 PRO A CA  
3594 C C   . PRO A 233 ? 0.13323 0.22243 0.20090 -0.00933 -0.06503 -0.00438 256 PRO A C   
3595 O O   . PRO A 233 ? 0.14921 0.24950 0.25193 -0.00622 -0.06071 0.00238  256 PRO A O   
3596 C CB  . PRO A 233 ? 0.31927 0.41405 0.37160 -0.01134 -0.06765 -0.00636 256 PRO A CB  
3597 C CG  . PRO A 233 ? 0.28859 0.38411 0.34814 -0.01525 -0.07139 -0.00076 256 PRO A CG  
3598 C CD  . PRO A 233 ? 0.25822 0.33966 0.31275 -0.01750 -0.07835 0.00445  256 PRO A CD  
3606 N N   . LEU A 234 ? 0.19761 0.27552 0.25881 -0.00840 -0.06762 -0.00842 257 LEU A N   
3607 C CA  . LEU A 234 ? 0.12797 0.20820 0.23324 0.00119  -0.06395 -0.01222 257 LEU A CA  
3608 C C   . LEU A 234 ? 0.12652 0.22978 0.22222 -0.00324 -0.04972 -0.00668 257 LEU A C   
3609 O O   . LEU A 234 ? 0.15402 0.25062 0.22176 -0.01004 -0.04993 -0.00292 257 LEU A O   
3610 C CB  . LEU A 234 ? 0.19267 0.20021 0.23664 0.00473  -0.04172 -0.02381 257 LEU A CB  
3611 C CG  . LEU A 234 ? 0.26618 0.21435 0.26087 -0.00376 -0.03483 -0.03048 257 LEU A CG  
3612 C CD1 . LEU A 234 ? 0.38482 0.27090 0.30899 -0.01420 -0.01520 -0.04378 257 LEU A CD1 
3613 C CD2 . LEU A 234 ? 0.27420 0.20974 0.31267 0.00764  -0.00722 -0.02357 257 LEU A CD2 
3625 N N   . ILE A 235 ? 0.12593 0.24923 0.24972 -0.00053 -0.03465 -0.00196 258 ILE A N   
3626 C CA  . ILE A 235 ? 0.11651 0.24291 0.23552 -0.00539 -0.02625 0.00101  258 ILE A CA  
3627 C C   . ILE A 235 ? 0.07208 0.18854 0.20863 0.00956  -0.00962 -0.01149 258 ILE A C   
3628 O O   . ILE A 235 ? 0.12853 0.23398 0.28000 0.01838  0.00857  -0.00003 258 ILE A O   
3629 C CB  . ILE A 235 ? 0.13431 0.25775 0.26799 -0.01240 -0.02016 -0.00836 258 ILE A CB  
3630 C CG1 . ILE A 235 ? 0.13823 0.26627 0.26493 -0.01946 -0.03076 -0.00569 258 ILE A CG1 
3631 C CG2 . ILE A 235 ? 0.13316 0.26014 0.26582 -0.01995 -0.01208 -0.00183 258 ILE A CG2 
3632 C CD1 . ILE A 235 ? 0.19730 0.31487 0.30729 -0.02239 -0.03518 -0.00661 258 ILE A CD1 
3644 N N   . LEU A 236 ? 0.14294 0.23843 0.24907 0.01170  -0.00599 -0.02274 259 LEU A N   
3645 C CA  . LEU A 236 ? 0.17702 0.23606 0.25715 0.02178  0.01403  -0.02528 259 LEU A CA  
3646 C C   . LEU A 236 ? 0.10137 0.17325 0.17995 0.01766  0.02082  -0.02847 259 LEU A C   
3647 O O   . LEU A 236 ? 0.12591 0.19803 0.19970 0.01400  0.01303  -0.03518 259 LEU A O   
3648 C CB  . LEU A 236 ? 0.16818 0.17429 0.19912 0.02432  0.01122  -0.03462 259 LEU A CB  
3649 C CG  . LEU A 236 ? 0.27726 0.24907 0.27754 0.02827  0.02974  -0.03985 259 LEU A CG  
3650 C CD1 . LEU A 236 ? 0.20338 0.16778 0.21926 0.03847  0.05671  -0.03482 259 LEU A CD1 
3651 C CD2 . LEU A 236 ? 0.27372 0.20088 0.22019 0.01665  0.02628  -0.04722 259 LEU A CD2 
3663 N N   . VAL A 237 ? 0.14888 0.23049 0.23363 0.01823  0.03831  -0.02043 260 VAL A N   
3664 C CA  . VAL A 237 ? 0.13304 0.21767 0.20519 0.01280  0.04798  -0.02349 260 VAL A CA  
3665 C C   . VAL A 237 ? 0.14150 0.19065 0.18485 0.02641  0.05843  -0.02474 260 VAL A C   
3666 O O   . VAL A 237 ? 0.14724 0.19217 0.19584 0.03474  0.07101  -0.01486 260 VAL A O   
3667 C CB  . VAL A 237 ? 0.10219 0.22757 0.19193 -0.00694 0.05400  -0.00676 260 VAL A CB  
3668 C CG1 . VAL A 237 ? 0.17257 0.28490 0.23451 -0.01250 0.06287  -0.00779 260 VAL A CG1 
3669 C CG2 . VAL A 237 ? 0.14708 0.27818 0.24294 -0.02290 0.03892  -0.00677 260 VAL A CG2 
3679 N N   . THR A 238 ? 0.18526 0.21067 0.20382 0.02792  0.05531  -0.03443 261 THR A N   
3680 C CA  . THR A 238 ? 0.17855 0.17846 0.16855 0.03401  0.06221  -0.03636 261 THR A CA  
3681 C C   . THR A 238 ? 0.17263 0.17994 0.15732 0.02906  0.06575  -0.03685 261 THR A C   
3682 O O   . THR A 238 ? 0.18875 0.19139 0.17984 0.02620  0.06076  -0.04037 261 THR A O   
3683 C CB  . THR A 238 ? 0.22644 0.19255 0.18906 0.03285  0.05238  -0.04279 261 THR A CB  
3684 O OG1 . THR A 238 ? 0.24414 0.21623 0.21570 0.02815  0.03767  -0.03955 261 THR A OG1 
3685 C CG2 . THR A 238 ? 0.21777 0.16414 0.17194 0.03223  0.05446  -0.04599 261 THR A CG2 
3693 N N   . TYR A 239 ? 0.19376 0.21201 0.16905 0.02820  0.07716  -0.02993 262 TYR A N   
3694 C CA  . TYR A 239 ? 0.19900 0.22568 0.16370 0.01860  0.07661  -0.02777 262 TYR A CA  
3695 C C   . TYR A 239 ? 0.20158 0.21452 0.14366 0.02459  0.07442  -0.02731 262 TYR A C   
3696 O O   . TYR A 239 ? 0.22757 0.23778 0.16683 0.03087  0.07774  -0.02264 262 TYR A O   
3697 C CB  . TYR A 239 ? 0.17692 0.23721 0.14915 0.00508  0.07760  -0.01027 262 TYR A CB  
3698 C CG  . TYR A 239 ? 0.21251 0.27812 0.19941 -0.01172 0.07682  -0.01298 262 TYR A CG  
3699 C CD1 . TYR A 239 ? 0.16981 0.22035 0.16575 -0.01181 0.07829  -0.03053 262 TYR A CD1 
3700 C CD2 . TYR A 239 ? 0.26677 0.34790 0.26043 -0.02731 0.07381  0.00123  262 TYR A CD2 
3701 C CE1 . TYR A 239 ? 0.19690 0.25315 0.20482 -0.02868 0.07871  -0.03570 262 TYR A CE1 
3702 C CE2 . TYR A 239 ? 0.25108 0.33728 0.25079 -0.04531 0.06961  -0.00664 262 TYR A CE2 
3703 C CZ  . TYR A 239 ? 0.18455 0.25819 0.18936 -0.04657 0.07339  -0.02614 262 TYR A CZ  
3704 O OH  . TYR A 239 ? 0.23595 0.30959 0.24209 -0.06456 0.07266  -0.03619 262 TYR A OH  
3714 N N   . PHE A 240 ? 0.24448 0.24591 0.17368 0.02244  0.07159  -0.03136 263 PHE A N   
3715 C CA  . PHE A 240 ? 0.25820 0.25162 0.16582 0.02455  0.06665  -0.03079 263 PHE A CA  
3716 C C   . PHE A 240 ? 0.23846 0.23559 0.13883 0.01748  0.06460  -0.02876 263 PHE A C   
3717 O O   . PHE A 240 ? 0.24296 0.22558 0.15055 0.01559  0.07241  -0.03237 263 PHE A O   
3718 C CB  . PHE A 240 ? 0.24979 0.21761 0.14357 0.02767  0.06053  -0.03718 263 PHE A CB  
3719 C CG  . PHE A 240 ? 0.25394 0.21619 0.11973 0.02285  0.05521  -0.03845 263 PHE A CG  
3720 C CD1 . PHE A 240 ? 0.26012 0.22728 0.12186 0.02395  0.06097  -0.03922 263 PHE A CD1 
3721 C CD2 . PHE A 240 ? 0.24302 0.20775 0.10964 0.01316  0.03981  -0.03322 263 PHE A CD2 
3722 C CE1 . PHE A 240 ? 0.30473 0.27325 0.14830 0.01723  0.05614  -0.04168 263 PHE A CE1 
3723 C CE2 . PHE A 240 ? 0.27054 0.23761 0.11153 0.00310  0.03188  -0.03413 263 PHE A CE2 
3724 C CZ  . PHE A 240 ? 0.32152 0.28818 0.14527 0.00583  0.04159  -0.04156 263 PHE A CZ  
3735 N N   . THR A 241 ? 0.25091 0.26410 0.14187 0.01203  0.05771  -0.02338 264 THR A N   
3736 C CA  . THR A 241 ? 0.25611 0.27510 0.13988 0.00764  0.05275  -0.01982 264 THR A CA  
3737 C C   . THR A 241 ? 0.27901 0.30259 0.15586 -0.00084 0.04181  -0.01730 264 THR A C   
3738 O O   . THR A 241 ? 0.27647 0.29187 0.14763 -0.00170 0.04418  -0.01610 264 THR A O   
3739 C CB  . THR A 241 ? 0.28458 0.31202 0.17377 0.00665  0.05512  -0.00804 264 THR A CB  
3740 O OG1 . THR A 241 ? 0.30706 0.32194 0.18412 -0.00149 0.05720  -0.00969 264 THR A OG1 
3741 C CG2 . THR A 241 ? 0.32101 0.33708 0.20163 0.00934  0.05759  0.00670  264 THR A CG2 
3749 N N   . GLN A 242 ? 0.26842 0.29769 0.14132 0.00187  0.03402  -0.01434 265 GLN A N   
3750 C CA  . GLN A 242 ? 0.25117 0.23755 0.09770 -0.01215 0.02680  -0.01213 265 GLN A CA  
3751 C C   . GLN A 242 ? 0.27393 0.25451 0.10891 0.00772  0.02213  -0.00286 265 GLN A C   
3752 O O   . GLN A 242 ? 0.33589 0.33695 0.17880 0.00882  0.02779  -0.00025 265 GLN A O   
3753 C CB  . GLN A 242 ? 0.30640 0.30605 0.14286 0.00833  0.01586  -0.01266 265 GLN A CB  
3754 C CG  . GLN A 242 ? 0.33677 0.33213 0.16415 0.00182  0.01877  -0.02016 265 GLN A CG  
3755 C CD  . GLN A 242 ? 0.27673 0.27637 0.12776 -0.01079 0.00083  -0.00956 265 GLN A CD  
3756 O OE1 . GLN A 242 ? 0.31070 0.32452 0.14800 -0.02725 -0.01613 -0.00628 265 GLN A OE1 
3757 N NE2 . GLN A 242 ? 0.29227 0.28707 0.18556 -0.00661 0.00467  0.00064  265 GLN A NE2 
3766 N N   . PRO A 243 ? 0.32481 0.31047 0.15280 0.00234  0.01228  -0.00178 266 PRO A N   
3767 C CA  . PRO A 243 ? 0.37905 0.37824 0.20381 0.00014  0.00840  0.00348  266 PRO A CA  
3768 C C   . PRO A 243 ? 0.32857 0.33072 0.15409 -0.00148 0.00317  0.00287  266 PRO A C   
3769 O O   . PRO A 243 ? 0.37997 0.39052 0.20510 -0.01017 0.00430  0.00595  266 PRO A O   
3770 C CB  . PRO A 243 ? 0.30543 0.31672 0.13141 -0.00145 0.00168  0.00448  266 PRO A CB  
3771 C CG  . PRO A 243 ? 0.34904 0.34850 0.16815 0.00003  0.00573  -0.00086 266 PRO A CG  
3772 C CD  . PRO A 243 ? 0.36521 0.35088 0.18875 0.00032  0.00925  -0.00518 266 PRO A CD  
3780 N N   . GLN A 244 ? 0.30420 0.30275 0.13267 0.00135  -0.00290 0.00062  267 GLN A N   
3781 C CA  . GLN A 244 ? 0.28745 0.28936 0.11615 -0.00282 -0.00795 0.00388  267 GLN A CA  
3782 C C   . GLN A 244 ? 0.32931 0.32208 0.14900 -0.01271 0.01124  0.00460  267 GLN A C   
3783 O O   . GLN A 244 ? 0.31406 0.29036 0.12576 -0.01863 0.02432  0.00241  267 GLN A O   
3784 C CB  . GLN A 244 ? 0.29862 0.31000 0.13842 -0.00749 -0.02682 0.00833  267 GLN A CB  
3785 C CG  . GLN A 244 ? 0.31013 0.33734 0.15907 -0.01463 -0.03593 0.00557  267 GLN A CG  
3786 C CD  . GLN A 244 ? 0.30843 0.33210 0.15277 -0.01224 -0.03338 -0.00003 267 GLN A CD  
3787 O OE1 . GLN A 244 ? 0.40486 0.41478 0.24225 -0.00456 -0.02610 -0.00205 267 GLN A OE1 
3788 N NE2 . GLN A 244 ? 0.33920 0.37502 0.18462 -0.02098 -0.03724 -0.00289 267 GLN A NE2 
3797 N N   . PRO A 245 ? 0.33190 0.30874 0.14064 -0.02389 0.02171  0.00487  268 PRO A N   
3798 C CA  . PRO A 245 ? 0.33389 0.25662 0.12459 -0.03927 0.06059  -0.00147 268 PRO A CA  
3799 C C   . PRO A 245 ? 0.33956 0.24801 0.19463 -0.02643 0.06867  0.01058  268 PRO A C   
3800 O O   . PRO A 245 ? 0.35488 0.23838 0.24203 -0.02086 0.09767  0.00474  268 PRO A O   
3801 C CB  . PRO A 245 ? 0.44472 0.34725 0.22137 -0.05209 0.06809  -0.00288 268 PRO A CB  
3802 C CG  . PRO A 245 ? 0.36533 0.32231 0.16000 -0.03971 0.03284  0.00215  268 PRO A CG  
3803 C CD  . PRO A 245 ? 0.31448 0.30066 0.12579 -0.02282 0.01074  0.00673  268 PRO A CD  
3811 N N   . LYS A 246 ? 0.30066 0.23762 0.19563 -0.02208 0.03844  0.03206  269 LYS A N   
3812 C CA  . LYS A 246 ? 0.29317 0.23708 0.27617 -0.01176 0.03884  0.05741  269 LYS A CA  
3813 C C   . LYS A 246 ? 0.26498 0.25072 0.26455 -0.01272 0.00863  0.06754  269 LYS A C   
3814 O O   . LYS A 246 ? 0.25627 0.27058 0.32052 -0.01554 -0.00656 0.09962  269 LYS A O   
3815 C CB  . LYS A 246 ? 0.31556 0.26774 0.34641 -0.01457 0.03007  0.08551  269 LYS A CB  
3816 C CG  . LYS A 246 ? 0.37358 0.27338 0.38765 -0.01663 0.06635  0.07503  269 LYS A CG  
3817 C CD  . LYS A 246 ? 0.52552 0.43393 0.60581 -0.01602 0.05964  0.10939  269 LYS A CD  
3818 C CE  . LYS A 246 ? 0.69641 0.54323 0.75035 -0.02163 0.09941  0.09578  269 LYS A CE  
3819 N NZ  . LYS A 246 ? 0.83803 0.69887 0.94558 -0.02294 0.08530  0.12880  269 LYS A NZ  
3833 N N   . ALA A 247 ? 0.25628 0.24716 0.19998 -0.01436 0.00237  0.04482  270 ALA A N   
3834 C CA  . ALA A 247 ? 0.28161 0.29796 0.23134 -0.01899 -0.01677 0.04841  270 ALA A CA  
3835 C C   . ALA A 247 ? 0.31066 0.32439 0.32282 -0.01226 -0.00622 0.06620  270 ALA A C   
3836 O O   . ALA A 247 ? 0.26420 0.24804 0.29889 0.00162  0.02387  0.06140  270 ALA A O   
3837 C CB  . ALA A 247 ? 0.31073 0.32021 0.20216 -0.01575 -0.01105 0.02174  270 ALA A CB  
3843 N N   . GLU A 248 ? 0.27947 0.32664 0.31519 -0.02717 -0.02982 0.08779  271 GLU A N   
3844 C CA  . GLU A 248 ? 0.23801 0.29187 0.32965 -0.02375 -0.02381 0.11203  271 GLU A CA  
3845 C C   . GLU A 248 ? 0.23852 0.27465 0.29626 -0.01794 -0.01478 0.08733  271 GLU A C   
3846 O O   . GLU A 248 ? 0.26545 0.29222 0.26341 -0.02122 -0.01717 0.05837  271 GLU A O   
3847 C CB  . GLU A 248 ? 0.29451 0.40096 0.42466 -0.05215 -0.05454 0.15518  271 GLU A CB  
3848 C CG  . GLU A 248 ? 0.54845 0.68189 0.72976 -0.05866 -0.06534 0.18892  271 GLU A CG  
3849 C CD  . GLU A 248 ? 0.63084 0.82995 0.87084 -0.09148 -0.09456 0.24656  271 GLU A CD  
3850 O OE1 . GLU A 248 ? 0.64241 0.85719 0.89970 -0.09792 -0.09736 0.26731  271 GLU A OE1 
3851 O OE2 . GLU A 248 ? 0.82624 1.04024 1.06495 -0.10482 -0.10982 0.26352  271 GLU A OE2 
3858 N N   . SER A 249 ? 0.23848 0.27016 0.34158 -0.00714 -0.00133 0.10188  272 SER A N   
3859 C CA  . SER A 249 ? 0.25533 0.27451 0.33358 -0.00270 0.00431  0.08266  272 SER A CA  
3860 C C   . SER A 249 ? 0.26244 0.29877 0.29923 -0.02702 -0.01950 0.08127  272 SER A C   
3861 O O   . SER A 249 ? 0.25213 0.32000 0.29614 -0.05369 -0.04162 0.10754  272 SER A O   
3862 C CB  . SER A 249 ? 0.45562 0.47606 0.59523 0.00952  0.01819  0.10602  272 SER A CB  
3863 O OG  . SER A 249 ? 0.60931 0.59677 0.76735 0.02927  0.05277  0.08965  272 SER A OG  
3869 N N   . ARG A 250 ? 0.24699 0.26207 0.24057 -0.02225 -0.01169 0.05156  273 ARG A N   
3870 C CA  . ARG A 250 ? 0.27635 0.29078 0.22351 -0.04509 -0.02227 0.04232  273 ARG A CA  
3871 C C   . ARG A 250 ? 0.27518 0.27679 0.22078 -0.03880 -0.01578 0.03623  273 ARG A C   
3872 O O   . ARG A 250 ? 0.28207 0.26038 0.19639 -0.02981 -0.00302 0.00927  273 ARG A O   
3873 C CB  . ARG A 250 ? 0.32171 0.31844 0.21630 -0.04508 -0.01432 0.01204  273 ARG A CB  
3874 C CG  . ARG A 250 ? 0.35666 0.37047 0.24265 -0.05794 -0.02624 0.01749  273 ARG A CG  
3875 C CD  . ARG A 250 ? 0.36380 0.40560 0.24477 -0.09964 -0.04876 0.03845  273 ARG A CD  
3876 N NE  . ARG A 250 ? 0.38223 0.40682 0.21066 -0.12706 -0.04351 0.02077  273 ARG A NE  
3877 C CZ  . ARG A 250 ? 0.52713 0.53278 0.30285 -0.14090 -0.03241 -0.00673 273 ARG A CZ  
3878 N NH1 . ARG A 250 ? 0.43919 0.44853 0.22070 -0.12395 -0.02903 -0.01503 273 ARG A NH1 
3879 N NH2 . ARG A 250 ? 0.48362 0.46355 0.22842 -0.16192 -0.01663 -0.02208 273 ARG A NH2 
3893 N N   . ARG A 251 ? 0.30259 0.22363 0.22093 0.03924  0.02532  0.05307  274 ARG A N   
3894 C CA  . ARG A 251 ? 0.24547 0.22213 0.18646 0.04501  0.00265  0.03963  274 ARG A CA  
3895 C C   . ARG A 251 ? 0.30127 0.30905 0.22783 0.03551  -0.00764 0.03712  274 ARG A C   
3896 O O   . ARG A 251 ? 0.23498 0.27583 0.18257 0.02779  -0.01754 0.02248  274 ARG A O   
3897 C CB  . ARG A 251 ? 0.27597 0.26577 0.21472 0.07476  -0.01310 0.05222  274 ARG A CB  
3898 C CG  . ARG A 251 ? 0.29189 0.24482 0.24326 0.08944  -0.00279 0.04790  274 ARG A CG  
3899 C CD  . ARG A 251 ? 0.44755 0.40485 0.38697 0.12885  -0.01277 0.06510  274 ARG A CD  
3900 N NE  . ARG A 251 ? 0.46107 0.36560 0.40661 0.14169  0.00134  0.05477  274 ARG A NE  
3901 C CZ  . ARG A 251 ? 0.63897 0.45797 0.55660 0.15096  0.02209  0.06743  274 ARG A CZ  
3902 N NH1 . ARG A 251 ? 0.57323 0.35883 0.45205 0.15987  0.03043  0.09998  274 ARG A NH1 
3903 N NH2 . ARG A 251 ? 0.56282 0.32632 0.48930 0.15119  0.03609  0.04673  274 ARG A NH2 
3917 N N   . ASP A 252 ? 0.26697 0.26027 0.15425 0.03707  -0.00350 0.05120  275 ASP A N   
3918 C CA  . ASP A 252 ? 0.30826 0.32442 0.17503 0.02902  -0.01281 0.04218  275 ASP A CA  
3919 C C   . ASP A 252 ? 0.31927 0.33654 0.20026 0.01243  -0.00100 0.02263  275 ASP A C   
3920 O O   . ASP A 252 ? 0.25027 0.27999 0.12577 0.00711  -0.00970 0.00807  275 ASP A O   
3921 C CB  . ASP A 252 ? 0.31745 0.32242 0.13541 0.03789  -0.00716 0.06012  275 ASP A CB  
3922 C CG  . ASP A 252 ? 0.43502 0.40414 0.24492 0.03108  0.02242  0.07254  275 ASP A CG  
3923 O OD1 . ASP A 252 ? 0.41895 0.35555 0.24557 0.03076  0.03573  0.08290  275 ASP A OD1 
3924 O OD2 . ASP A 252 ? 0.48380 0.45769 0.27118 0.02422  0.03385  0.07022  275 ASP A OD2 
3929 N N   . VAL A 253 ? 0.27062 0.27552 0.16889 0.00447  0.01981  0.02133  276 VAL A N   
3930 C CA  . VAL A 253 ? 0.28624 0.30979 0.20188 -0.00496 0.03115  0.00427  276 VAL A CA  
3931 C C   . VAL A 253 ? 0.28115 0.32922 0.22899 -0.00203 0.01958  -0.00931 276 VAL A C   
3932 O O   . VAL A 253 ? 0.23212 0.29084 0.17863 0.00002  0.02043  -0.01885 276 VAL A O   
3933 C CB  . VAL A 253 ? 0.28621 0.30806 0.21897 -0.01878 0.05424  0.00416  276 VAL A CB  
3934 C CG1 . VAL A 253 ? 0.25718 0.32068 0.21527 -0.02345 0.06363  -0.01408 276 VAL A CG1 
3935 C CG2 . VAL A 253 ? 0.32132 0.32216 0.21932 -0.02344 0.07067  0.02284  276 VAL A CG2 
3945 N N   . LEU A 254 ? 0.21858 0.27352 0.19146 0.00222  0.01011  -0.00785 277 LEU A N   
3946 C CA  . LEU A 254 ? 0.18104 0.26646 0.18289 0.00668  0.00066  -0.01536 277 LEU A CA  
3947 C C   . LEU A 254 ? 0.18936 0.27654 0.17879 0.00531  -0.01521 -0.01205 277 LEU A C   
3948 O O   . LEU A 254 ? 0.18163 0.27840 0.18215 0.00376  -0.01513 -0.01651 277 LEU A O   
3949 C CB  . LEU A 254 ? 0.20769 0.30692 0.23633 0.01500  -0.00500 -0.01555 277 LEU A CB  
3950 C CG  . LEU A 254 ? 0.16434 0.24793 0.20242 0.01094  0.00904  -0.02392 277 LEU A CG  
3951 C CD1 . LEU A 254 ? 0.17433 0.26933 0.23419 0.02507  0.00159  -0.02971 277 LEU A CD1 
3952 C CD2 . LEU A 254 ? 0.13084 0.23810 0.18368 -0.00153 0.02445  -0.03936 277 LEU A CD2 
3964 N N   . ALA A 255 ? 0.21208 0.29190 0.17839 0.00518  -0.02820 -0.00399 278 ALA A N   
3965 C CA  . ALA A 255 ? 0.20705 0.29508 0.16227 -0.00460 -0.04458 -0.00740 278 ALA A CA  
3966 C C   . ALA A 255 ? 0.25504 0.31426 0.18449 -0.01300 -0.03651 -0.02101 278 ALA A C   
3967 O O   . ALA A 255 ? 0.22630 0.27766 0.15904 -0.02398 -0.04065 -0.02937 278 ALA A O   
3968 C CB  . ALA A 255 ? 0.21336 0.31463 0.14517 -0.00047 -0.06071 0.00146  278 ALA A CB  
3974 N N   . SER A 256 ? 0.25405 0.29452 0.15707 -0.00697 -0.02221 -0.02237 279 SER A N   
3975 C CA  . SER A 256 ? 0.26713 0.28315 0.14048 -0.00638 -0.01193 -0.03600 279 SER A CA  
3976 C C   . SER A 256 ? 0.23939 0.25257 0.13431 -0.00001 0.00181  -0.04078 279 SER A C   
3977 O O   . SER A 256 ? 0.27522 0.25939 0.15239 0.00119  0.00481  -0.05141 279 SER A O   
3978 C CB  . SER A 256 ? 0.29697 0.30957 0.14167 0.00144  0.00320  -0.03165 279 SER A CB  
3979 O OG  . SER A 256 ? 0.35608 0.36936 0.16845 0.00160  -0.00791 -0.02512 279 SER A OG  
3985 N N   . ALA A 257 ? 0.23044 0.27214 0.15999 0.00638  0.01126  -0.03393 280 ALA A N   
3986 C CA  . ALA A 257 ? 0.20244 0.25720 0.15166 0.01855  0.02336  -0.03548 280 ALA A CA  
3987 C C   . ALA A 257 ? 0.23863 0.28352 0.20134 0.01485  0.01423  -0.03122 280 ALA A C   
3988 O O   . ALA A 257 ? 0.23484 0.25656 0.18868 0.02424  0.02422  -0.03133 280 ALA A O   
3989 C CB  . ALA A 257 ? 0.19212 0.28852 0.17844 0.02212  0.02970  -0.03202 280 ALA A CB  
3995 N N   . ALA A 258 ? 0.18631 0.24802 0.16925 0.00266  -0.00247 -0.02491 281 ALA A N   
3996 C CA  . ALA A 258 ? 0.19288 0.25480 0.19241 -0.00716 -0.01028 -0.01805 281 ALA A CA  
3997 C C   . ALA A 258 ? 0.27616 0.28516 0.24400 -0.02348 -0.01264 -0.02799 281 ALA A C   
3998 O O   . ALA A 258 ? 0.24298 0.22312 0.21276 -0.02657 -0.00411 -0.02403 281 ALA A O   
3999 C CB  . ALA A 258 ? 0.18496 0.28588 0.20868 -0.01610 -0.02863 -0.01036 281 ALA A CB  
4005 N N   A LYS A 259 ? 0.23209 0.22496 0.16767 -0.03388 -0.02325 -0.04140 282 LYS A N   
4006 N N   B LYS A 259 ? 0.23217 0.22504 0.16778 -0.03395 -0.02329 -0.04140 282 LYS A N   
4007 C CA  A LYS A 259 ? 0.31228 0.25515 0.21263 -0.05109 -0.02725 -0.05996 282 LYS A CA  
4008 C CA  B LYS A 259 ? 0.31212 0.25475 0.21278 -0.05116 -0.02714 -0.05986 282 LYS A CA  
4009 C C   A LYS A 259 ? 0.33826 0.22577 0.21192 -0.03277 -0.00467 -0.06726 282 LYS A C   
4010 C C   B LYS A 259 ? 0.33806 0.22565 0.21229 -0.03262 -0.00447 -0.06696 282 LYS A C   
4011 O O   A LYS A 259 ? 0.38025 0.21157 0.23923 -0.04367 0.00016  -0.07579 282 LYS A O   
4012 O O   B LYS A 259 ? 0.37884 0.21067 0.23932 -0.04314 0.00071  -0.07481 282 LYS A O   
4013 C CB  A LYS A 259 ? 0.35441 0.30442 0.21979 -0.05669 -0.04151 -0.07373 282 LYS A CB  
4014 C CB  B LYS A 259 ? 0.35512 0.30392 0.22043 -0.05730 -0.04155 -0.07412 282 LYS A CB  
4015 C CG  A LYS A 259 ? 0.46657 0.37045 0.28901 -0.07443 -0.04803 -0.10195 282 LYS A CG  
4016 C CG  B LYS A 259 ? 0.46704 0.36818 0.29042 -0.07559 -0.04771 -0.10231 282 LYS A CG  
4017 C CD  A LYS A 259 ? 0.40146 0.31861 0.24800 -0.10776 -0.06644 -0.10765 282 LYS A CD  
4018 C CD  B LYS A 259 ? 0.43215 0.35618 0.22704 -0.06615 -0.05735 -0.11165 282 LYS A CD  
4019 C CE  A LYS A 259 ? 0.53853 0.42490 0.35889 -0.11921 -0.07285 -0.13593 282 LYS A CE  
4020 C CE  B LYS A 259 ? 0.59712 0.48975 0.36814 -0.07679 -0.06343 -0.14028 282 LYS A CE  
4021 N NZ  A LYS A 259 ? 0.79014 0.70632 0.58137 -0.10014 -0.08219 -0.14448 282 LYS A NZ  
4022 N NZ  B LYS A 259 ? 0.77913 0.68762 0.57765 -0.10865 -0.08245 -0.14611 282 LYS A NZ  
4048 N N   . ILE A 260 ? 0.34681 0.24905 0.21321 -0.00461 0.01093  -0.06378 283 ILE A N   
4049 C CA  . ILE A 260 ? 0.34871 0.21235 0.18707 0.02162  0.03313  -0.06947 283 ILE A CA  
4050 C C   . ILE A 260 ? 0.35747 0.20439 0.21599 0.03444  0.04717  -0.05388 283 ILE A C   
4051 O O   . ILE A 260 ? 0.42183 0.20325 0.25067 0.04698  0.06174  -0.05854 283 ILE A O   
4052 C CB  . ILE A 260 ? 0.38855 0.29673 0.22486 0.04595  0.04664  -0.06620 283 ILE A CB  
4053 C CG1 . ILE A 260 ? 0.37282 0.28567 0.18161 0.03737  0.03914  -0.07658 283 ILE A CG1 
4054 C CG2 . ILE A 260 ? 0.41502 0.32142 0.25216 0.07404  0.06512  -0.06078 283 ILE A CG2 
4055 C CD1 . ILE A 260 ? 0.34682 0.31654 0.18200 0.04041  0.04813  -0.06330 283 ILE A CD1 
4067 N N   . VAL A 261 ? 0.33793 0.24048 0.24268 0.03566  0.04511  -0.03428 284 VAL A N   
4068 C CA  . VAL A 261 ? 0.33011 0.23064 0.25013 0.05764  0.06221  -0.01450 284 VAL A CA  
4069 C C   . VAL A 261 ? 0.36844 0.22531 0.29686 0.03283  0.05909  -0.00425 284 VAL A C   
4070 O O   . VAL A 261 ? 0.37189 0.20575 0.30303 0.05078  0.07752  0.01628  284 VAL A O   
4071 C CB  . VAL A 261 ? 0.28893 0.27715 0.25120 0.07553  0.06429  -0.00009 284 VAL A CB  
4072 C CG1 . VAL A 261 ? 0.30200 0.32976 0.26289 0.08434  0.06417  -0.01012 284 VAL A CG1 
4073 C CG2 . VAL A 261 ? 0.24301 0.27522 0.24133 0.05022  0.04396  0.00299  284 VAL A CG2 
4083 N N   . THR A 262 ? 0.33541 0.18481 0.26800 -0.00772 0.03795  -0.01557 285 THR A N   
4084 C CA  . THR A 262 ? 0.37648 0.19333 0.32166 -0.04095 0.03494  -0.00789 285 THR A CA  
4085 C C   . THR A 262 ? 0.47213 0.19875 0.37604 -0.06876 0.03368  -0.03386 285 THR A C   
4086 O O   . THR A 262 ? 0.56773 0.25220 0.47902 -0.10341 0.03487  -0.03098 285 THR A O   
4087 C CB  . THR A 262 ? 0.34400 0.23519 0.33096 -0.06883 0.01184  -0.00152 285 THR A CB  
4088 O OG1 . THR A 262 ? 0.30985 0.22336 0.28319 -0.08183 -0.00993 -0.02358 285 THR A OG1 
4089 C CG2 . THR A 262 ? 0.24463 0.21348 0.26997 -0.04084 0.01579  0.02144  285 THR A CG2 
4097 N N   . ASP A 263 ? 0.51632 0.21267 0.37623 -0.05550 0.03307  -0.06024 286 ASP A N   
4098 C CA  . ASP A 263 ? 0.67585 0.28465 0.48791 -0.07637 0.03216  -0.09281 286 ASP A CA  
4099 C C   . ASP A 263 ? 0.73178 0.25225 0.53081 -0.06762 0.05693  -0.08336 286 ASP A C   
4100 O O   . ASP A 263 ? 0.95899 0.46040 0.74568 -0.02034 0.08169  -0.06497 286 ASP A O   
4101 C CB  . ASP A 263 ? 0.68904 0.29903 0.45785 -0.04757 0.03243  -0.11530 286 ASP A CB  
4102 C CG  . ASP A 263 ? 0.90339 0.47295 0.64507 -0.05760 0.02601  -0.14397 286 ASP A CG  
4103 O OD1 . ASP A 263 ? 0.94662 0.53668 0.69788 -0.09488 0.00278  -0.16204 286 ASP A OD1 
4104 O OD2 . ASP A 263 ? 1.14318 0.66954 0.85613 -0.02543 0.04374  -0.14904 286 ASP A OD2 
4109 N N   . GLY A 264 ? 0.88768 0.37463 0.69729 -0.10860 0.04860  -0.09260 287 GLY A N   
4110 C CA  . GLY A 264 ? 0.97144 0.37972 0.77579 -0.10569 0.06937  -0.08036 287 GLY A CA  
4111 C C   . GLY A 264 ? 1.06653 0.48514 0.91637 -0.13308 0.07477  -0.04633 287 GLY A C   
4112 O O   . GLY A 264 ? 0.99763 0.35611 0.85091 -0.15244 0.08343  -0.04085 287 GLY A O   
4116 N N   . LEU A 265 ? 0.98807 0.48341 0.87347 -0.13497 0.07073  -0.02223 288 LEU A N   
4117 C CA  . LEU A 265 ? 1.04754 0.57830 0.98248 -0.16315 0.07297  0.01150  288 LEU A CA  
4118 C C   . LEU A 265 ? 0.99712 0.57266 0.96501 -0.22229 0.04440  -0.00896 288 LEU A C   
4119 O O   . LEU A 265 ? 1.12296 0.76363 1.09456 -0.23391 0.01892  -0.03311 288 LEU A O   
4120 C CB  . LEU A 265 ? 0.79506 0.41655 0.76283 -0.13637 0.07742  0.04360  288 LEU A CB  
4121 C CG  . LEU A 265 ? 0.70747 0.34360 0.65636 -0.06725 0.09335  0.05449  288 LEU A CG  
4122 C CD1 . LEU A 265 ? 0.61977 0.38382 0.61223 -0.04578 0.08070  0.07027  288 LEU A CD1 
4123 C CD2 . LEU A 265 ? 0.90183 0.46597 0.83036 -0.03112 0.12932  0.08578  288 LEU A CD2 
# 
