data_9R2E
# 
_entry.id   9R2E 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9R2E         pdb_00009r2e 10.2210/pdb9r2e/pdb 
WWPDB D_1292147446 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-05-14 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9R2E 
_pdbx_database_status.recvd_initial_deposition_date   2025-04-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              epannecoucke@argenx.com 
_pdbx_contact_author.name_first         Erwin 
_pdbx_contact_author.name_last          Pannecoucke 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3014-1851 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Pannecoucke, E.' 1  0000-0003-3014-1851 
'Voet, S.'        2  ?                   
'Deweirdt, L.'    3  ?                   
'Verbeiren, J.'   4  ?                   
'Gabriels, S.'    5  ?                   
'Provost, M.'     6  0000-0002-7831-1170 
'Freier, R.'      7  0000-0002-8202-5599 
'Koenig, J.'      8  ?                   
'Lammens, A.'     9  0000-0002-4837-4277 
'Silence, K.'     10 ?                   
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of ARGX-121 Fab fragment in complex with the Fc fragment of IgA1' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Voet, S.'        1 ? 
primary 'Provost, M.'     2 ? 
primary 'Deweirdt, L.'    3 ? 
primary 'Verbeiren, J.'   4 ? 
primary 'Gabriels, S.'    5 ? 
primary 'Silence, K.'     6 ? 
primary 'Pannecoucke, E.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'ARGX-121 Fab fragment heavy chain'                  25904.072 2   ? ? ? ? 
2 polymer     man 'ARGX-121 Fab fragment light chain'                  24725.676 2   ? ? ? ? 
3 polymer     man 'Isoform 1 of Immunoglobulin heavy constant alpha 1' 23155.314 2   ? ? ? ? 
4 non-polymer syn 1,2-ETHANEDIOL                                       62.068    4   ? ? ? ? 
5 non-polymer syn 'DI(HYDROXYETHYL)ETHER'                              106.120   5   ? ? ? ? 
6 non-polymer syn 'MAGNESIUM ION'                                      24.305    3   ? ? ? ? 
7 water       nat water                                                18.015    377 ? ? ? ? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        'Ig alpha-1 chain C region,Ig alpha-1 chain C region BUR,Ig alpha-1 chain C region TRO' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGWSCIILFLVATATGVHSEVQLLESGGGLVQPGGSLRLSCAASGFTSSNYLMSWVRQAPGKGLEWVSSIYHYGHNAYYA
DSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKVDSAYDFGSWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTA
ALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
DKTH
;
;MGWSCIILFLVATATGVHSEVQLLESGGGLVQPGGSLRLSCAASGFTSSNYLMSWVRQAPGKGLEWVSSIYHYGHNAYYA
DSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKVDSAYDFGSWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTA
ALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
DKTH
;
H,A ? 
2 'polypeptide(L)' no no 
;MGWSCIILFLVATATGVHSQSVLTQPPSVSGAPGQRVTISCAGTSSDIGGRTYVSWYQQLPGTAPKLLIYKVTIRASGVP
DRFSGSKSGTSASLAITGLQAEDEADYYCASHRSNNNIVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLIS
DFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
;
;MGWSCIILFLVATATGVHSQSVLTQPPSVSGAPGQRVTISCAGTSSDIGGRTYVSWYQQLPGTAPKLLIYKVTIRASGVP
DRFSGSKSGTSASLAITGLQAEDEADYYCASHRSNNNIVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLIS
DFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
;
L,B ? 
3 'polypeptide(L)' no no 
;CHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGVTFTWTPSSGKSAVQGPPERDLCGCYSVSSVLPGCAEPWNHGKTF
TCTAAYPESKTPLTATLSKSGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASR
QEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGK
;
;CHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGVTFTWTPSSGKSAVQGPPERDLCGCYSVSSVLPGCAEPWNHGKTF
TCTAAYPESKTPLTATLSKSGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASR
QEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGK
;
P,Q ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 1,2-ETHANEDIOL          EDO 
5 'DI(HYDROXYETHYL)ETHER' PEG 
6 'MAGNESIUM ION'         MG  
7 water                   HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   TRP n 
1 4   SER n 
1 5   CYS n 
1 6   ILE n 
1 7   ILE n 
1 8   LEU n 
1 9   PHE n 
1 10  LEU n 
1 11  VAL n 
1 12  ALA n 
1 13  THR n 
1 14  ALA n 
1 15  THR n 
1 16  GLY n 
1 17  VAL n 
1 18  HIS n 
1 19  SER n 
1 20  GLU n 
1 21  VAL n 
1 22  GLN n 
1 23  LEU n 
1 24  LEU n 
1 25  GLU n 
1 26  SER n 
1 27  GLY n 
1 28  GLY n 
1 29  GLY n 
1 30  LEU n 
1 31  VAL n 
1 32  GLN n 
1 33  PRO n 
1 34  GLY n 
1 35  GLY n 
1 36  SER n 
1 37  LEU n 
1 38  ARG n 
1 39  LEU n 
1 40  SER n 
1 41  CYS n 
1 42  ALA n 
1 43  ALA n 
1 44  SER n 
1 45  GLY n 
1 46  PHE n 
1 47  THR n 
1 48  SER n 
1 49  SER n 
1 50  ASN n 
1 51  TYR n 
1 52  LEU n 
1 53  MET n 
1 54  SER n 
1 55  TRP n 
1 56  VAL n 
1 57  ARG n 
1 58  GLN n 
1 59  ALA n 
1 60  PRO n 
1 61  GLY n 
1 62  LYS n 
1 63  GLY n 
1 64  LEU n 
1 65  GLU n 
1 66  TRP n 
1 67  VAL n 
1 68  SER n 
1 69  SER n 
1 70  ILE n 
1 71  TYR n 
1 72  HIS n 
1 73  TYR n 
1 74  GLY n 
1 75  HIS n 
1 76  ASN n 
1 77  ALA n 
1 78  TYR n 
1 79  TYR n 
1 80  ALA n 
1 81  ASP n 
1 82  SER n 
1 83  VAL n 
1 84  LYS n 
1 85  GLY n 
1 86  ARG n 
1 87  PHE n 
1 88  THR n 
1 89  ILE n 
1 90  SER n 
1 91  ARG n 
1 92  ASP n 
1 93  ASN n 
1 94  SER n 
1 95  LYS n 
1 96  ASN n 
1 97  THR n 
1 98  LEU n 
1 99  TYR n 
1 100 LEU n 
1 101 GLN n 
1 102 MET n 
1 103 ASN n 
1 104 SER n 
1 105 LEU n 
1 106 ARG n 
1 107 ALA n 
1 108 GLU n 
1 109 ASP n 
1 110 THR n 
1 111 ALA n 
1 112 VAL n 
1 113 TYR n 
1 114 TYR n 
1 115 CYS n 
1 116 ALA n 
1 117 LYS n 
1 118 VAL n 
1 119 ASP n 
1 120 SER n 
1 121 ALA n 
1 122 TYR n 
1 123 ASP n 
1 124 PHE n 
1 125 GLY n 
1 126 SER n 
1 127 TRP n 
1 128 GLY n 
1 129 GLN n 
1 130 GLY n 
1 131 THR n 
1 132 LEU n 
1 133 VAL n 
1 134 THR n 
1 135 VAL n 
1 136 SER n 
1 137 SER n 
1 138 ALA n 
1 139 SER n 
1 140 THR n 
1 141 LYS n 
1 142 GLY n 
1 143 PRO n 
1 144 SER n 
1 145 VAL n 
1 146 PHE n 
1 147 PRO n 
1 148 LEU n 
1 149 ALA n 
1 150 PRO n 
1 151 SER n 
1 152 SER n 
1 153 LYS n 
1 154 SER n 
1 155 THR n 
1 156 SER n 
1 157 GLY n 
1 158 GLY n 
1 159 THR n 
1 160 ALA n 
1 161 ALA n 
1 162 LEU n 
1 163 GLY n 
1 164 CYS n 
1 165 LEU n 
1 166 VAL n 
1 167 LYS n 
1 168 ASP n 
1 169 TYR n 
1 170 PHE n 
1 171 PRO n 
1 172 GLU n 
1 173 PRO n 
1 174 VAL n 
1 175 THR n 
1 176 VAL n 
1 177 SER n 
1 178 TRP n 
1 179 ASN n 
1 180 SER n 
1 181 GLY n 
1 182 ALA n 
1 183 LEU n 
1 184 THR n 
1 185 SER n 
1 186 GLY n 
1 187 VAL n 
1 188 HIS n 
1 189 THR n 
1 190 PHE n 
1 191 PRO n 
1 192 ALA n 
1 193 VAL n 
1 194 LEU n 
1 195 GLN n 
1 196 SER n 
1 197 SER n 
1 198 GLY n 
1 199 LEU n 
1 200 TYR n 
1 201 SER n 
1 202 LEU n 
1 203 SER n 
1 204 SER n 
1 205 VAL n 
1 206 VAL n 
1 207 THR n 
1 208 VAL n 
1 209 PRO n 
1 210 SER n 
1 211 SER n 
1 212 SER n 
1 213 LEU n 
1 214 GLY n 
1 215 THR n 
1 216 GLN n 
1 217 THR n 
1 218 TYR n 
1 219 ILE n 
1 220 CYS n 
1 221 ASN n 
1 222 VAL n 
1 223 ASN n 
1 224 HIS n 
1 225 LYS n 
1 226 PRO n 
1 227 SER n 
1 228 ASN n 
1 229 THR n 
1 230 LYS n 
1 231 VAL n 
1 232 ASP n 
1 233 LYS n 
1 234 LYS n 
1 235 VAL n 
1 236 GLU n 
1 237 PRO n 
1 238 LYS n 
1 239 SER n 
1 240 CYS n 
1 241 ASP n 
1 242 LYS n 
1 243 THR n 
1 244 HIS n 
2 1   MET n 
2 2   GLY n 
2 3   TRP n 
2 4   SER n 
2 5   CYS n 
2 6   ILE n 
2 7   ILE n 
2 8   LEU n 
2 9   PHE n 
2 10  LEU n 
2 11  VAL n 
2 12  ALA n 
2 13  THR n 
2 14  ALA n 
2 15  THR n 
2 16  GLY n 
2 17  VAL n 
2 18  HIS n 
2 19  SER n 
2 20  GLN n 
2 21  SER n 
2 22  VAL n 
2 23  LEU n 
2 24  THR n 
2 25  GLN n 
2 26  PRO n 
2 27  PRO n 
2 28  SER n 
2 29  VAL n 
2 30  SER n 
2 31  GLY n 
2 32  ALA n 
2 33  PRO n 
2 34  GLY n 
2 35  GLN n 
2 36  ARG n 
2 37  VAL n 
2 38  THR n 
2 39  ILE n 
2 40  SER n 
2 41  CYS n 
2 42  ALA n 
2 43  GLY n 
2 44  THR n 
2 45  SER n 
2 46  SER n 
2 47  ASP n 
2 48  ILE n 
2 49  GLY n 
2 50  GLY n 
2 51  ARG n 
2 52  THR n 
2 53  TYR n 
2 54  VAL n 
2 55  SER n 
2 56  TRP n 
2 57  TYR n 
2 58  GLN n 
2 59  GLN n 
2 60  LEU n 
2 61  PRO n 
2 62  GLY n 
2 63  THR n 
2 64  ALA n 
2 65  PRO n 
2 66  LYS n 
2 67  LEU n 
2 68  LEU n 
2 69  ILE n 
2 70  TYR n 
2 71  LYS n 
2 72  VAL n 
2 73  THR n 
2 74  ILE n 
2 75  ARG n 
2 76  ALA n 
2 77  SER n 
2 78  GLY n 
2 79  VAL n 
2 80  PRO n 
2 81  ASP n 
2 82  ARG n 
2 83  PHE n 
2 84  SER n 
2 85  GLY n 
2 86  SER n 
2 87  LYS n 
2 88  SER n 
2 89  GLY n 
2 90  THR n 
2 91  SER n 
2 92  ALA n 
2 93  SER n 
2 94  LEU n 
2 95  ALA n 
2 96  ILE n 
2 97  THR n 
2 98  GLY n 
2 99  LEU n 
2 100 GLN n 
2 101 ALA n 
2 102 GLU n 
2 103 ASP n 
2 104 GLU n 
2 105 ALA n 
2 106 ASP n 
2 107 TYR n 
2 108 TYR n 
2 109 CYS n 
2 110 ALA n 
2 111 SER n 
2 112 HIS n 
2 113 ARG n 
2 114 SER n 
2 115 ASN n 
2 116 ASN n 
2 117 ASN n 
2 118 ILE n 
2 119 VAL n 
2 120 PHE n 
2 121 GLY n 
2 122 GLY n 
2 123 GLY n 
2 124 THR n 
2 125 LYS n 
2 126 LEU n 
2 127 THR n 
2 128 VAL n 
2 129 LEU n 
2 130 GLY n 
2 131 GLN n 
2 132 PRO n 
2 133 LYS n 
2 134 ALA n 
2 135 ALA n 
2 136 PRO n 
2 137 SER n 
2 138 VAL n 
2 139 THR n 
2 140 LEU n 
2 141 PHE n 
2 142 PRO n 
2 143 PRO n 
2 144 SER n 
2 145 SER n 
2 146 GLU n 
2 147 GLU n 
2 148 LEU n 
2 149 GLN n 
2 150 ALA n 
2 151 ASN n 
2 152 LYS n 
2 153 ALA n 
2 154 THR n 
2 155 LEU n 
2 156 VAL n 
2 157 CYS n 
2 158 LEU n 
2 159 ILE n 
2 160 SER n 
2 161 ASP n 
2 162 PHE n 
2 163 TYR n 
2 164 PRO n 
2 165 GLY n 
2 166 ALA n 
2 167 VAL n 
2 168 THR n 
2 169 VAL n 
2 170 ALA n 
2 171 TRP n 
2 172 LYS n 
2 173 ALA n 
2 174 ASP n 
2 175 SER n 
2 176 SER n 
2 177 PRO n 
2 178 VAL n 
2 179 LYS n 
2 180 ALA n 
2 181 GLY n 
2 182 VAL n 
2 183 GLU n 
2 184 THR n 
2 185 THR n 
2 186 THR n 
2 187 PRO n 
2 188 SER n 
2 189 LYS n 
2 190 GLN n 
2 191 SER n 
2 192 ASN n 
2 193 ASN n 
2 194 LYS n 
2 195 TYR n 
2 196 ALA n 
2 197 ALA n 
2 198 SER n 
2 199 SER n 
2 200 TYR n 
2 201 LEU n 
2 202 SER n 
2 203 LEU n 
2 204 THR n 
2 205 PRO n 
2 206 GLU n 
2 207 GLN n 
2 208 TRP n 
2 209 LYS n 
2 210 SER n 
2 211 HIS n 
2 212 ARG n 
2 213 SER n 
2 214 TYR n 
2 215 SER n 
2 216 CYS n 
2 217 GLN n 
2 218 VAL n 
2 219 THR n 
2 220 HIS n 
2 221 GLU n 
2 222 GLY n 
2 223 SER n 
2 224 THR n 
2 225 VAL n 
2 226 GLU n 
2 227 LYS n 
2 228 THR n 
2 229 VAL n 
2 230 ALA n 
2 231 PRO n 
2 232 THR n 
2 233 GLU n 
2 234 CYS n 
2 235 SER n 
3 1   CYS n 
3 2   HIS n 
3 3   PRO n 
3 4   ARG n 
3 5   LEU n 
3 6   SER n 
3 7   LEU n 
3 8   HIS n 
3 9   ARG n 
3 10  PRO n 
3 11  ALA n 
3 12  LEU n 
3 13  GLU n 
3 14  ASP n 
3 15  LEU n 
3 16  LEU n 
3 17  LEU n 
3 18  GLY n 
3 19  SER n 
3 20  GLU n 
3 21  ALA n 
3 22  ASN n 
3 23  LEU n 
3 24  THR n 
3 25  CYS n 
3 26  THR n 
3 27  LEU n 
3 28  THR n 
3 29  GLY n 
3 30  LEU n 
3 31  ARG n 
3 32  ASP n 
3 33  ALA n 
3 34  SER n 
3 35  GLY n 
3 36  VAL n 
3 37  THR n 
3 38  PHE n 
3 39  THR n 
3 40  TRP n 
3 41  THR n 
3 42  PRO n 
3 43  SER n 
3 44  SER n 
3 45  GLY n 
3 46  LYS n 
3 47  SER n 
3 48  ALA n 
3 49  VAL n 
3 50  GLN n 
3 51  GLY n 
3 52  PRO n 
3 53  PRO n 
3 54  GLU n 
3 55  ARG n 
3 56  ASP n 
3 57  LEU n 
3 58  CYS n 
3 59  GLY n 
3 60  CYS n 
3 61  TYR n 
3 62  SER n 
3 63  VAL n 
3 64  SER n 
3 65  SER n 
3 66  VAL n 
3 67  LEU n 
3 68  PRO n 
3 69  GLY n 
3 70  CYS n 
3 71  ALA n 
3 72  GLU n 
3 73  PRO n 
3 74  TRP n 
3 75  ASN n 
3 76  HIS n 
3 77  GLY n 
3 78  LYS n 
3 79  THR n 
3 80  PHE n 
3 81  THR n 
3 82  CYS n 
3 83  THR n 
3 84  ALA n 
3 85  ALA n 
3 86  TYR n 
3 87  PRO n 
3 88  GLU n 
3 89  SER n 
3 90  LYS n 
3 91  THR n 
3 92  PRO n 
3 93  LEU n 
3 94  THR n 
3 95  ALA n 
3 96  THR n 
3 97  LEU n 
3 98  SER n 
3 99  LYS n 
3 100 SER n 
3 101 GLY n 
3 102 ASN n 
3 103 THR n 
3 104 PHE n 
3 105 ARG n 
3 106 PRO n 
3 107 GLU n 
3 108 VAL n 
3 109 HIS n 
3 110 LEU n 
3 111 LEU n 
3 112 PRO n 
3 113 PRO n 
3 114 PRO n 
3 115 SER n 
3 116 GLU n 
3 117 GLU n 
3 118 LEU n 
3 119 ALA n 
3 120 LEU n 
3 121 ASN n 
3 122 GLU n 
3 123 LEU n 
3 124 VAL n 
3 125 THR n 
3 126 LEU n 
3 127 THR n 
3 128 CYS n 
3 129 LEU n 
3 130 ALA n 
3 131 ARG n 
3 132 GLY n 
3 133 PHE n 
3 134 SER n 
3 135 PRO n 
3 136 LYS n 
3 137 ASP n 
3 138 VAL n 
3 139 LEU n 
3 140 VAL n 
3 141 ARG n 
3 142 TRP n 
3 143 LEU n 
3 144 GLN n 
3 145 GLY n 
3 146 SER n 
3 147 GLN n 
3 148 GLU n 
3 149 LEU n 
3 150 PRO n 
3 151 ARG n 
3 152 GLU n 
3 153 LYS n 
3 154 TYR n 
3 155 LEU n 
3 156 THR n 
3 157 TRP n 
3 158 ALA n 
3 159 SER n 
3 160 ARG n 
3 161 GLN n 
3 162 GLU n 
3 163 PRO n 
3 164 SER n 
3 165 GLN n 
3 166 GLY n 
3 167 THR n 
3 168 THR n 
3 169 THR n 
3 170 PHE n 
3 171 ALA n 
3 172 VAL n 
3 173 THR n 
3 174 SER n 
3 175 ILE n 
3 176 LEU n 
3 177 ARG n 
3 178 VAL n 
3 179 ALA n 
3 180 ALA n 
3 181 GLU n 
3 182 ASP n 
3 183 TRP n 
3 184 LYS n 
3 185 LYS n 
3 186 GLY n 
3 187 ASP n 
3 188 THR n 
3 189 PHE n 
3 190 SER n 
3 191 CYS n 
3 192 MET n 
3 193 VAL n 
3 194 GLY n 
3 195 HIS n 
3 196 GLU n 
3 197 ALA n 
3 198 LEU n 
3 199 PRO n 
3 200 LEU n 
3 201 ALA n 
3 202 PHE n 
3 203 THR n 
3 204 GLN n 
3 205 LYS n 
3 206 THR n 
3 207 ILE n 
3 208 ASP n 
3 209 ARG n 
3 210 LEU n 
3 211 ALA n 
3 212 GLY n 
3 213 LYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 244 ?     ? ?     ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Cricetulus griseus' 10029 ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 235 ?     ? ?     ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Cricetulus griseus' 10029 ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 213 human ? IGHA1 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens'       9606  ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                 ?                 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                ?                 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE              ?                 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'         ?                 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                ?                 'C3 H7 N O2 S'   121.158 
EDO non-polymer         . 1,2-ETHANEDIOL          'ETHYLENE GLYCOL' 'C2 H6 O2'       62.068  
GLN 'L-peptide linking' y GLUTAMINE               ?                 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'         ?                 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                 ?                 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE               ?                 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                   ?                 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE              ?                 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                 ?                 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                  ?                 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE              ?                 'C5 H11 N O2 S'  149.211 
MG  non-polymer         . 'MAGNESIUM ION'         ?                 'Mg 2'           24.305  
PEG non-polymer         . 'DI(HYDROXYETHYL)ETHER' ?                 'C4 H10 O3'      106.120 
PHE 'L-peptide linking' y PHENYLALANINE           ?                 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                 ?                 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                  ?                 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE               ?                 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN              ?                 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                ?                 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                  ?                 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -17 ?   ?   ?   H . n 
A 1 2   GLY 2   -16 ?   ?   ?   H . n 
A 1 3   TRP 3   -15 ?   ?   ?   H . n 
A 1 4   SER 4   -14 ?   ?   ?   H . n 
A 1 5   CYS 5   -13 ?   ?   ?   H . n 
A 1 6   ILE 6   -12 ?   ?   ?   H . n 
A 1 7   ILE 7   -11 ?   ?   ?   H . n 
A 1 8   LEU 8   -10 ?   ?   ?   H . n 
A 1 9   PHE 9   -9  ?   ?   ?   H . n 
A 1 10  LEU 10  -8  ?   ?   ?   H . n 
A 1 11  VAL 11  -7  ?   ?   ?   H . n 
A 1 12  ALA 12  -6  ?   ?   ?   H . n 
A 1 13  THR 13  -5  ?   ?   ?   H . n 
A 1 14  ALA 14  -4  ?   ?   ?   H . n 
A 1 15  THR 15  -3  ?   ?   ?   H . n 
A 1 16  GLY 16  -2  ?   ?   ?   H . n 
A 1 17  VAL 17  -1  ?   ?   ?   H . n 
A 1 18  HIS 18  0   ?   ?   ?   H . n 
A 1 19  SER 19  1   ?   ?   ?   H . n 
A 1 20  GLU 20  2   2   GLU GLU H . n 
A 1 21  VAL 21  3   3   VAL VAL H . n 
A 1 22  GLN 22  4   4   GLN GLN H . n 
A 1 23  LEU 23  5   5   LEU LEU H . n 
A 1 24  LEU 24  6   6   LEU LEU H . n 
A 1 25  GLU 25  7   7   GLU GLU H . n 
A 1 26  SER 26  8   8   SER SER H . n 
A 1 27  GLY 27  9   9   GLY GLY H . n 
A 1 28  GLY 28  10  10  GLY GLY H . n 
A 1 29  GLY 29  11  11  GLY GLY H . n 
A 1 30  LEU 30  12  12  LEU LEU H . n 
A 1 31  VAL 31  13  13  VAL VAL H . n 
A 1 32  GLN 32  14  14  GLN GLN H . n 
A 1 33  PRO 33  15  15  PRO PRO H . n 
A 1 34  GLY 34  16  16  GLY GLY H . n 
A 1 35  GLY 35  17  17  GLY GLY H . n 
A 1 36  SER 36  18  18  SER SER H . n 
A 1 37  LEU 37  19  19  LEU LEU H . n 
A 1 38  ARG 38  20  20  ARG ARG H . n 
A 1 39  LEU 39  21  21  LEU LEU H . n 
A 1 40  SER 40  22  22  SER SER H . n 
A 1 41  CYS 41  23  23  CYS CYS H . n 
A 1 42  ALA 42  24  24  ALA ALA H . n 
A 1 43  ALA 43  25  25  ALA ALA H . n 
A 1 44  SER 44  26  26  SER SER H . n 
A 1 45  GLY 45  27  27  GLY GLY H . n 
A 1 46  PHE 46  28  28  PHE PHE H . n 
A 1 47  THR 47  29  29  THR THR H . n 
A 1 48  SER 48  30  30  SER SER H . n 
A 1 49  SER 49  31  31  SER SER H . n 
A 1 50  ASN 50  32  32  ASN ASN H . n 
A 1 51  TYR 51  33  33  TYR TYR H . n 
A 1 52  LEU 52  34  34  LEU LEU H . n 
A 1 53  MET 53  35  35  MET MET H . n 
A 1 54  SER 54  36  36  SER SER H . n 
A 1 55  TRP 55  37  37  TRP TRP H . n 
A 1 56  VAL 56  38  38  VAL VAL H . n 
A 1 57  ARG 57  39  39  ARG ARG H . n 
A 1 58  GLN 58  40  40  GLN GLN H . n 
A 1 59  ALA 59  41  41  ALA ALA H . n 
A 1 60  PRO 60  42  42  PRO PRO H . n 
A 1 61  GLY 61  43  43  GLY GLY H . n 
A 1 62  LYS 62  44  44  LYS LYS H . n 
A 1 63  GLY 63  45  45  GLY GLY H . n 
A 1 64  LEU 64  46  46  LEU LEU H . n 
A 1 65  GLU 65  47  47  GLU GLU H . n 
A 1 66  TRP 66  48  48  TRP TRP H . n 
A 1 67  VAL 67  49  49  VAL VAL H . n 
A 1 68  SER 68  50  50  SER SER H . n 
A 1 69  SER 69  51  51  SER SER H . n 
A 1 70  ILE 70  52  52  ILE ILE H . n 
A 1 71  TYR 71  53  53  TYR TYR H . n 
A 1 72  HIS 72  54  54  HIS HIS H . n 
A 1 73  TYR 73  55  55  TYR TYR H . n 
A 1 74  GLY 74  56  56  GLY GLY H . n 
A 1 75  HIS 75  57  57  HIS HIS H . n 
A 1 76  ASN 76  58  58  ASN ASN H . n 
A 1 77  ALA 77  59  59  ALA ALA H . n 
A 1 78  TYR 78  60  60  TYR TYR H . n 
A 1 79  TYR 79  61  61  TYR TYR H . n 
A 1 80  ALA 80  62  62  ALA ALA H . n 
A 1 81  ASP 81  63  63  ASP ASP H . n 
A 1 82  SER 82  64  64  SER SER H . n 
A 1 83  VAL 83  65  65  VAL VAL H . n 
A 1 84  LYS 84  66  66  LYS LYS H . n 
A 1 85  GLY 85  67  67  GLY GLY H . n 
A 1 86  ARG 86  68  68  ARG ARG H . n 
A 1 87  PHE 87  69  69  PHE PHE H . n 
A 1 88  THR 88  70  70  THR THR H . n 
A 1 89  ILE 89  71  71  ILE ILE H . n 
A 1 90  SER 90  72  72  SER SER H . n 
A 1 91  ARG 91  73  73  ARG ARG H . n 
A 1 92  ASP 92  74  74  ASP ASP H . n 
A 1 93  ASN 93  75  75  ASN ASN H . n 
A 1 94  SER 94  76  76  SER SER H . n 
A 1 95  LYS 95  77  77  LYS LYS H . n 
A 1 96  ASN 96  78  78  ASN ASN H . n 
A 1 97  THR 97  79  79  THR THR H . n 
A 1 98  LEU 98  80  80  LEU LEU H . n 
A 1 99  TYR 99  81  81  TYR TYR H . n 
A 1 100 LEU 100 82  82  LEU LEU H . n 
A 1 101 GLN 101 83  83  GLN GLN H . n 
A 1 102 MET 102 84  84  MET MET H . n 
A 1 103 ASN 103 85  85  ASN ASN H . n 
A 1 104 SER 104 86  86  SER SER H . n 
A 1 105 LEU 105 87  87  LEU LEU H . n 
A 1 106 ARG 106 88  88  ARG ARG H . n 
A 1 107 ALA 107 89  89  ALA ALA H . n 
A 1 108 GLU 108 90  90  GLU GLU H . n 
A 1 109 ASP 109 91  91  ASP ASP H . n 
A 1 110 THR 110 92  92  THR THR H . n 
A 1 111 ALA 111 93  93  ALA ALA H . n 
A 1 112 VAL 112 94  94  VAL VAL H . n 
A 1 113 TYR 113 95  95  TYR TYR H . n 
A 1 114 TYR 114 96  96  TYR TYR H . n 
A 1 115 CYS 115 97  97  CYS CYS H . n 
A 1 116 ALA 116 98  98  ALA ALA H . n 
A 1 117 LYS 117 99  99  LYS LYS H . n 
A 1 118 VAL 118 100 100 VAL VAL H . n 
A 1 119 ASP 119 101 101 ASP ASP H . n 
A 1 120 SER 120 102 102 SER SER H . n 
A 1 121 ALA 121 103 103 ALA ALA H . n 
A 1 122 TYR 122 104 104 TYR TYR H . n 
A 1 123 ASP 123 105 105 ASP ASP H . n 
A 1 124 PHE 124 106 106 PHE PHE H . n 
A 1 125 GLY 125 107 107 GLY GLY H . n 
A 1 126 SER 126 108 108 SER SER H . n 
A 1 127 TRP 127 109 109 TRP TRP H . n 
A 1 128 GLY 128 110 110 GLY GLY H . n 
A 1 129 GLN 129 111 111 GLN GLN H . n 
A 1 130 GLY 130 112 112 GLY GLY H . n 
A 1 131 THR 131 113 113 THR THR H . n 
A 1 132 LEU 132 114 114 LEU LEU H . n 
A 1 133 VAL 133 115 115 VAL VAL H . n 
A 1 134 THR 134 116 116 THR THR H . n 
A 1 135 VAL 135 117 117 VAL VAL H . n 
A 1 136 SER 136 118 118 SER SER H . n 
A 1 137 SER 137 119 119 SER SER H . n 
A 1 138 ALA 138 120 120 ALA ALA H . n 
A 1 139 SER 139 121 121 SER SER H . n 
A 1 140 THR 140 122 122 THR THR H . n 
A 1 141 LYS 141 123 123 LYS LYS H . n 
A 1 142 GLY 142 124 124 GLY GLY H . n 
A 1 143 PRO 143 125 125 PRO PRO H . n 
A 1 144 SER 144 126 126 SER SER H . n 
A 1 145 VAL 145 127 127 VAL VAL H . n 
A 1 146 PHE 146 128 128 PHE PHE H . n 
A 1 147 PRO 147 129 129 PRO PRO H . n 
A 1 148 LEU 148 130 130 LEU LEU H . n 
A 1 149 ALA 149 131 131 ALA ALA H . n 
A 1 150 PRO 150 132 132 PRO PRO H . n 
A 1 151 SER 151 133 133 SER SER H . n 
A 1 152 SER 152 134 134 SER SER H . n 
A 1 153 LYS 153 135 135 LYS LYS H . n 
A 1 154 SER 154 136 136 SER SER H . n 
A 1 155 THR 155 137 137 THR THR H . n 
A 1 156 SER 156 138 138 SER SER H . n 
A 1 157 GLY 157 139 139 GLY GLY H . n 
A 1 158 GLY 158 140 140 GLY GLY H . n 
A 1 159 THR 159 141 141 THR THR H . n 
A 1 160 ALA 160 142 142 ALA ALA H . n 
A 1 161 ALA 161 143 143 ALA ALA H . n 
A 1 162 LEU 162 144 144 LEU LEU H . n 
A 1 163 GLY 163 145 145 GLY GLY H . n 
A 1 164 CYS 164 146 146 CYS CYS H . n 
A 1 165 LEU 165 147 147 LEU LEU H . n 
A 1 166 VAL 166 148 148 VAL VAL H . n 
A 1 167 LYS 167 149 149 LYS LYS H . n 
A 1 168 ASP 168 150 150 ASP ASP H . n 
A 1 169 TYR 169 151 151 TYR TYR H . n 
A 1 170 PHE 170 152 152 PHE PHE H . n 
A 1 171 PRO 171 153 153 PRO PRO H . n 
A 1 172 GLU 172 154 154 GLU GLU H . n 
A 1 173 PRO 173 155 155 PRO PRO H . n 
A 1 174 VAL 174 156 156 VAL VAL H . n 
A 1 175 THR 175 157 157 THR THR H . n 
A 1 176 VAL 176 158 158 VAL VAL H . n 
A 1 177 SER 177 159 159 SER SER H . n 
A 1 178 TRP 178 160 160 TRP TRP H . n 
A 1 179 ASN 179 161 161 ASN ASN H . n 
A 1 180 SER 180 162 162 SER SER H . n 
A 1 181 GLY 181 163 163 GLY GLY H . n 
A 1 182 ALA 182 164 164 ALA ALA H . n 
A 1 183 LEU 183 165 165 LEU LEU H . n 
A 1 184 THR 184 166 166 THR THR H . n 
A 1 185 SER 185 167 167 SER SER H . n 
A 1 186 GLY 186 168 168 GLY GLY H . n 
A 1 187 VAL 187 169 169 VAL VAL H . n 
A 1 188 HIS 188 170 170 HIS HIS H . n 
A 1 189 THR 189 171 171 THR THR H . n 
A 1 190 PHE 190 172 172 PHE PHE H . n 
A 1 191 PRO 191 173 173 PRO PRO H . n 
A 1 192 ALA 192 174 174 ALA ALA H . n 
A 1 193 VAL 193 175 175 VAL VAL H . n 
A 1 194 LEU 194 176 176 LEU LEU H . n 
A 1 195 GLN 195 177 177 GLN GLN H . n 
A 1 196 SER 196 178 178 SER SER H . n 
A 1 197 SER 197 179 179 SER SER H . n 
A 1 198 GLY 198 180 180 GLY GLY H . n 
A 1 199 LEU 199 181 181 LEU LEU H . n 
A 1 200 TYR 200 182 182 TYR TYR H . n 
A 1 201 SER 201 183 183 SER SER H . n 
A 1 202 LEU 202 184 184 LEU LEU H . n 
A 1 203 SER 203 185 185 SER SER H . n 
A 1 204 SER 204 186 186 SER SER H . n 
A 1 205 VAL 205 187 187 VAL VAL H . n 
A 1 206 VAL 206 188 188 VAL VAL H . n 
A 1 207 THR 207 189 189 THR THR H . n 
A 1 208 VAL 208 190 190 VAL VAL H . n 
A 1 209 PRO 209 191 191 PRO PRO H . n 
A 1 210 SER 210 192 192 SER SER H . n 
A 1 211 SER 211 193 193 SER SER H . n 
A 1 212 SER 212 194 194 SER SER H . n 
A 1 213 LEU 213 195 195 LEU LEU H . n 
A 1 214 GLY 214 196 196 GLY GLY H . n 
A 1 215 THR 215 197 197 THR THR H . n 
A 1 216 GLN 216 198 198 GLN GLN H . n 
A 1 217 THR 217 199 199 THR THR H . n 
A 1 218 TYR 218 200 200 TYR TYR H . n 
A 1 219 ILE 219 201 201 ILE ILE H . n 
A 1 220 CYS 220 202 202 CYS CYS H . n 
A 1 221 ASN 221 203 203 ASN ASN H . n 
A 1 222 VAL 222 204 204 VAL VAL H . n 
A 1 223 ASN 223 205 205 ASN ASN H . n 
A 1 224 HIS 224 206 206 HIS HIS H . n 
A 1 225 LYS 225 207 207 LYS LYS H . n 
A 1 226 PRO 226 208 208 PRO PRO H . n 
A 1 227 SER 227 209 209 SER SER H . n 
A 1 228 ASN 228 210 210 ASN ASN H . n 
A 1 229 THR 229 211 211 THR THR H . n 
A 1 230 LYS 230 212 212 LYS LYS H . n 
A 1 231 VAL 231 213 213 VAL VAL H . n 
A 1 232 ASP 232 214 214 ASP ASP H . n 
A 1 233 LYS 233 215 215 LYS LYS H . n 
A 1 234 LYS 234 216 216 LYS LYS H . n 
A 1 235 VAL 235 217 217 VAL VAL H . n 
A 1 236 GLU 236 218 218 GLU GLU H . n 
A 1 237 PRO 237 219 219 PRO PRO H . n 
A 1 238 LYS 238 220 220 LYS LYS H . n 
A 1 239 SER 239 221 221 SER SER H . n 
A 1 240 CYS 240 222 222 CYS CYS H . n 
A 1 241 ASP 241 223 223 ASP ASP H . n 
A 1 242 LYS 242 224 224 LYS LYS H . n 
A 1 243 THR 243 225 225 THR THR H . n 
A 1 244 HIS 244 226 ?   ?   ?   H . n 
B 2 1   MET 1   -18 ?   ?   ?   L . n 
B 2 2   GLY 2   -17 ?   ?   ?   L . n 
B 2 3   TRP 3   -16 ?   ?   ?   L . n 
B 2 4   SER 4   -15 ?   ?   ?   L . n 
B 2 5   CYS 5   -14 ?   ?   ?   L . n 
B 2 6   ILE 6   -13 ?   ?   ?   L . n 
B 2 7   ILE 7   -12 ?   ?   ?   L . n 
B 2 8   LEU 8   -11 ?   ?   ?   L . n 
B 2 9   PHE 9   -10 ?   ?   ?   L . n 
B 2 10  LEU 10  -9  ?   ?   ?   L . n 
B 2 11  VAL 11  -8  ?   ?   ?   L . n 
B 2 12  ALA 12  -7  ?   ?   ?   L . n 
B 2 13  THR 13  -6  ?   ?   ?   L . n 
B 2 14  ALA 14  -5  ?   ?   ?   L . n 
B 2 15  THR 15  -4  ?   ?   ?   L . n 
B 2 16  GLY 16  -3  ?   ?   ?   L . n 
B 2 17  VAL 17  -2  ?   ?   ?   L . n 
B 2 18  HIS 18  -1  ?   ?   ?   L . n 
B 2 19  SER 19  0   ?   ?   ?   L . n 
B 2 20  GLN 20  1   ?   ?   ?   L . n 
B 2 21  SER 21  2   2   SER SER L . n 
B 2 22  VAL 22  3   3   VAL VAL L . n 
B 2 23  LEU 23  4   4   LEU LEU L . n 
B 2 24  THR 24  5   5   THR THR L . n 
B 2 25  GLN 25  6   6   GLN GLN L . n 
B 2 26  PRO 26  7   7   PRO PRO L . n 
B 2 27  PRO 27  8   8   PRO PRO L . n 
B 2 28  SER 28  9   9   SER SER L . n 
B 2 29  VAL 29  10  10  VAL VAL L . n 
B 2 30  SER 30  11  11  SER SER L . n 
B 2 31  GLY 31  12  12  GLY GLY L . n 
B 2 32  ALA 32  13  13  ALA ALA L . n 
B 2 33  PRO 33  14  14  PRO PRO L . n 
B 2 34  GLY 34  15  15  GLY GLY L . n 
B 2 35  GLN 35  16  16  GLN GLN L . n 
B 2 36  ARG 36  17  17  ARG ARG L . n 
B 2 37  VAL 37  18  18  VAL VAL L . n 
B 2 38  THR 38  19  19  THR THR L . n 
B 2 39  ILE 39  20  20  ILE ILE L . n 
B 2 40  SER 40  21  21  SER SER L . n 
B 2 41  CYS 41  22  22  CYS CYS L . n 
B 2 42  ALA 42  23  23  ALA ALA L . n 
B 2 43  GLY 43  24  24  GLY GLY L . n 
B 2 44  THR 44  25  25  THR THR L . n 
B 2 45  SER 45  26  26  SER SER L . n 
B 2 46  SER 46  27  27  SER SER L . n 
B 2 47  ASP 47  28  28  ASP ASP L . n 
B 2 48  ILE 48  29  29  ILE ILE L . n 
B 2 49  GLY 49  30  30  GLY GLY L . n 
B 2 50  GLY 50  31  31  GLY GLY L . n 
B 2 51  ARG 51  32  32  ARG ARG L . n 
B 2 52  THR 52  33  33  THR THR L . n 
B 2 53  TYR 53  34  34  TYR TYR L . n 
B 2 54  VAL 54  35  35  VAL VAL L . n 
B 2 55  SER 55  36  36  SER SER L . n 
B 2 56  TRP 56  37  37  TRP TRP L . n 
B 2 57  TYR 57  38  38  TYR TYR L . n 
B 2 58  GLN 58  39  39  GLN GLN L . n 
B 2 59  GLN 59  40  40  GLN GLN L . n 
B 2 60  LEU 60  41  41  LEU LEU L . n 
B 2 61  PRO 61  42  42  PRO PRO L . n 
B 2 62  GLY 62  43  43  GLY GLY L . n 
B 2 63  THR 63  44  44  THR THR L . n 
B 2 64  ALA 64  45  45  ALA ALA L . n 
B 2 65  PRO 65  46  46  PRO PRO L . n 
B 2 66  LYS 66  47  47  LYS LYS L . n 
B 2 67  LEU 67  48  48  LEU LEU L . n 
B 2 68  LEU 68  49  49  LEU LEU L . n 
B 2 69  ILE 69  50  50  ILE ILE L . n 
B 2 70  TYR 70  51  51  TYR TYR L . n 
B 2 71  LYS 71  52  52  LYS LYS L . n 
B 2 72  VAL 72  53  53  VAL VAL L . n 
B 2 73  THR 73  54  54  THR THR L . n 
B 2 74  ILE 74  55  55  ILE ILE L . n 
B 2 75  ARG 75  56  56  ARG ARG L . n 
B 2 76  ALA 76  57  57  ALA ALA L . n 
B 2 77  SER 77  58  58  SER SER L . n 
B 2 78  GLY 78  59  59  GLY GLY L . n 
B 2 79  VAL 79  60  60  VAL VAL L . n 
B 2 80  PRO 80  61  61  PRO PRO L . n 
B 2 81  ASP 81  62  62  ASP ASP L . n 
B 2 82  ARG 82  63  63  ARG ARG L . n 
B 2 83  PHE 83  64  64  PHE PHE L . n 
B 2 84  SER 84  65  65  SER SER L . n 
B 2 85  GLY 85  66  66  GLY GLY L . n 
B 2 86  SER 86  67  67  SER SER L . n 
B 2 87  LYS 87  68  68  LYS LYS L . n 
B 2 88  SER 88  69  69  SER SER L . n 
B 2 89  GLY 89  70  70  GLY GLY L . n 
B 2 90  THR 90  71  71  THR THR L . n 
B 2 91  SER 91  72  72  SER SER L . n 
B 2 92  ALA 92  73  73  ALA ALA L . n 
B 2 93  SER 93  74  74  SER SER L . n 
B 2 94  LEU 94  75  75  LEU LEU L . n 
B 2 95  ALA 95  76  76  ALA ALA L . n 
B 2 96  ILE 96  77  77  ILE ILE L . n 
B 2 97  THR 97  78  78  THR THR L . n 
B 2 98  GLY 98  79  79  GLY GLY L . n 
B 2 99  LEU 99  80  80  LEU LEU L . n 
B 2 100 GLN 100 81  81  GLN GLN L . n 
B 2 101 ALA 101 82  82  ALA ALA L . n 
B 2 102 GLU 102 83  83  GLU GLU L . n 
B 2 103 ASP 103 84  84  ASP ASP L . n 
B 2 104 GLU 104 85  85  GLU GLU L . n 
B 2 105 ALA 105 86  86  ALA ALA L . n 
B 2 106 ASP 106 87  87  ASP ASP L . n 
B 2 107 TYR 107 88  88  TYR TYR L . n 
B 2 108 TYR 108 89  89  TYR TYR L . n 
B 2 109 CYS 109 90  90  CYS CYS L . n 
B 2 110 ALA 110 91  91  ALA ALA L . n 
B 2 111 SER 111 92  92  SER SER L . n 
B 2 112 HIS 112 93  93  HIS HIS L . n 
B 2 113 ARG 113 94  94  ARG ARG L . n 
B 2 114 SER 114 95  95  SER SER L . n 
B 2 115 ASN 115 96  96  ASN ASN L . n 
B 2 116 ASN 116 97  97  ASN ASN L . n 
B 2 117 ASN 117 98  98  ASN ASN L . n 
B 2 118 ILE 118 99  99  ILE ILE L . n 
B 2 119 VAL 119 100 100 VAL VAL L . n 
B 2 120 PHE 120 101 101 PHE PHE L . n 
B 2 121 GLY 121 102 102 GLY GLY L . n 
B 2 122 GLY 122 103 103 GLY GLY L . n 
B 2 123 GLY 123 104 104 GLY GLY L . n 
B 2 124 THR 124 105 105 THR THR L . n 
B 2 125 LYS 125 106 106 LYS LYS L . n 
B 2 126 LEU 126 107 107 LEU LEU L . n 
B 2 127 THR 127 108 108 THR THR L . n 
B 2 128 VAL 128 109 109 VAL VAL L . n 
B 2 129 LEU 129 110 110 LEU LEU L . n 
B 2 130 GLY 130 111 111 GLY GLY L . n 
B 2 131 GLN 131 112 112 GLN GLN L . n 
B 2 132 PRO 132 113 113 PRO PRO L . n 
B 2 133 LYS 133 114 114 LYS LYS L . n 
B 2 134 ALA 134 115 115 ALA ALA L . n 
B 2 135 ALA 135 116 116 ALA ALA L . n 
B 2 136 PRO 136 117 117 PRO PRO L . n 
B 2 137 SER 137 118 118 SER SER L . n 
B 2 138 VAL 138 119 119 VAL VAL L . n 
B 2 139 THR 139 120 120 THR THR L . n 
B 2 140 LEU 140 121 121 LEU LEU L . n 
B 2 141 PHE 141 122 122 PHE PHE L . n 
B 2 142 PRO 142 123 123 PRO PRO L . n 
B 2 143 PRO 143 124 124 PRO PRO L . n 
B 2 144 SER 144 125 125 SER SER L . n 
B 2 145 SER 145 126 126 SER SER L . n 
B 2 146 GLU 146 127 127 GLU GLU L . n 
B 2 147 GLU 147 128 128 GLU GLU L . n 
B 2 148 LEU 148 129 129 LEU LEU L . n 
B 2 149 GLN 149 130 130 GLN GLN L . n 
B 2 150 ALA 150 131 131 ALA ALA L . n 
B 2 151 ASN 151 132 132 ASN ASN L . n 
B 2 152 LYS 152 133 133 LYS LYS L . n 
B 2 153 ALA 153 134 134 ALA ALA L . n 
B 2 154 THR 154 135 135 THR THR L . n 
B 2 155 LEU 155 136 136 LEU LEU L . n 
B 2 156 VAL 156 137 137 VAL VAL L . n 
B 2 157 CYS 157 138 138 CYS CYS L . n 
B 2 158 LEU 158 139 139 LEU LEU L . n 
B 2 159 ILE 159 140 140 ILE ILE L . n 
B 2 160 SER 160 141 141 SER SER L . n 
B 2 161 ASP 161 142 142 ASP ASP L . n 
B 2 162 PHE 162 143 143 PHE PHE L . n 
B 2 163 TYR 163 144 144 TYR TYR L . n 
B 2 164 PRO 164 145 145 PRO PRO L . n 
B 2 165 GLY 165 146 146 GLY GLY L . n 
B 2 166 ALA 166 147 147 ALA ALA L . n 
B 2 167 VAL 167 148 148 VAL VAL L . n 
B 2 168 THR 168 149 149 THR THR L . n 
B 2 169 VAL 169 150 150 VAL VAL L . n 
B 2 170 ALA 170 151 151 ALA ALA L . n 
B 2 171 TRP 171 152 152 TRP TRP L . n 
B 2 172 LYS 172 153 153 LYS LYS L . n 
B 2 173 ALA 173 154 154 ALA ALA L . n 
B 2 174 ASP 174 155 155 ASP ASP L . n 
B 2 175 SER 175 156 156 SER SER L . n 
B 2 176 SER 176 157 157 SER SER L . n 
B 2 177 PRO 177 158 158 PRO PRO L . n 
B 2 178 VAL 178 159 159 VAL VAL L . n 
B 2 179 LYS 179 160 160 LYS LYS L . n 
B 2 180 ALA 180 161 161 ALA ALA L . n 
B 2 181 GLY 181 162 162 GLY GLY L . n 
B 2 182 VAL 182 163 163 VAL VAL L . n 
B 2 183 GLU 183 164 164 GLU GLU L . n 
B 2 184 THR 184 165 165 THR THR L . n 
B 2 185 THR 185 166 166 THR THR L . n 
B 2 186 THR 186 167 167 THR THR L . n 
B 2 187 PRO 187 168 168 PRO PRO L . n 
B 2 188 SER 188 169 169 SER SER L . n 
B 2 189 LYS 189 170 170 LYS LYS L . n 
B 2 190 GLN 190 171 171 GLN GLN L . n 
B 2 191 SER 191 172 172 SER SER L . n 
B 2 192 ASN 192 173 173 ASN ASN L . n 
B 2 193 ASN 193 174 174 ASN ASN L . n 
B 2 194 LYS 194 175 175 LYS LYS L . n 
B 2 195 TYR 195 176 176 TYR TYR L . n 
B 2 196 ALA 196 177 177 ALA ALA L . n 
B 2 197 ALA 197 178 178 ALA ALA L . n 
B 2 198 SER 198 179 179 SER SER L . n 
B 2 199 SER 199 180 180 SER SER L . n 
B 2 200 TYR 200 181 181 TYR TYR L . n 
B 2 201 LEU 201 182 182 LEU LEU L . n 
B 2 202 SER 202 183 183 SER SER L . n 
B 2 203 LEU 203 184 184 LEU LEU L . n 
B 2 204 THR 204 185 185 THR THR L . n 
B 2 205 PRO 205 186 186 PRO PRO L . n 
B 2 206 GLU 206 187 187 GLU GLU L . n 
B 2 207 GLN 207 188 188 GLN GLN L . n 
B 2 208 TRP 208 189 189 TRP TRP L . n 
B 2 209 LYS 209 190 190 LYS LYS L . n 
B 2 210 SER 210 191 191 SER SER L . n 
B 2 211 HIS 211 192 192 HIS HIS L . n 
B 2 212 ARG 212 193 193 ARG ARG L . n 
B 2 213 SER 213 194 194 SER SER L . n 
B 2 214 TYR 214 195 195 TYR TYR L . n 
B 2 215 SER 215 196 196 SER SER L . n 
B 2 216 CYS 216 197 197 CYS CYS L . n 
B 2 217 GLN 217 198 198 GLN GLN L . n 
B 2 218 VAL 218 199 199 VAL VAL L . n 
B 2 219 THR 219 200 200 THR THR L . n 
B 2 220 HIS 220 201 201 HIS HIS L . n 
B 2 221 GLU 221 202 202 GLU GLU L . n 
B 2 222 GLY 222 203 203 GLY GLY L . n 
B 2 223 SER 223 204 204 SER SER L . n 
B 2 224 THR 224 205 205 THR THR L . n 
B 2 225 VAL 225 206 206 VAL VAL L . n 
B 2 226 GLU 226 207 207 GLU GLU L . n 
B 2 227 LYS 227 208 208 LYS LYS L . n 
B 2 228 THR 228 209 209 THR THR L . n 
B 2 229 VAL 229 210 210 VAL VAL L . n 
B 2 230 ALA 230 211 211 ALA ALA L . n 
B 2 231 PRO 231 212 212 PRO PRO L . n 
B 2 232 THR 232 213 213 THR THR L . n 
B 2 233 GLU 233 214 214 GLU GLU L . n 
B 2 234 CYS 234 215 215 CYS CYS L . n 
B 2 235 SER 235 216 ?   ?   ?   L . n 
C 3 1   CYS 1   242 242 CYS CYS P . n 
C 3 2   HIS 2   243 243 HIS HIS P . n 
C 3 3   PRO 3   244 244 PRO PRO P . n 
C 3 4   ARG 4   245 245 ARG ARG P . n 
C 3 5   LEU 5   246 246 LEU LEU P . n 
C 3 6   SER 6   247 247 SER SER P . n 
C 3 7   LEU 7   248 248 LEU LEU P . n 
C 3 8   HIS 8   249 249 HIS HIS P . n 
C 3 9   ARG 9   250 250 ARG ARG P . n 
C 3 10  PRO 10  251 251 PRO PRO P . n 
C 3 11  ALA 11  252 252 ALA ALA P . n 
C 3 12  LEU 12  253 253 LEU LEU P . n 
C 3 13  GLU 13  254 254 GLU GLU P . n 
C 3 14  ASP 14  255 255 ASP ASP P . n 
C 3 15  LEU 15  256 256 LEU LEU P . n 
C 3 16  LEU 16  257 257 LEU LEU P . n 
C 3 17  LEU 17  258 258 LEU LEU P . n 
C 3 18  GLY 18  259 259 GLY GLY P . n 
C 3 19  SER 19  260 260 SER SER P . n 
C 3 20  GLU 20  261 261 GLU GLU P . n 
C 3 21  ALA 21  262 262 ALA ALA P . n 
C 3 22  ASN 22  263 263 ASN ASN P . n 
C 3 23  LEU 23  264 264 LEU LEU P . n 
C 3 24  THR 24  265 265 THR THR P . n 
C 3 25  CYS 25  266 266 CYS CYS P . n 
C 3 26  THR 26  267 267 THR THR P . n 
C 3 27  LEU 27  268 268 LEU LEU P . n 
C 3 28  THR 28  269 269 THR THR P . n 
C 3 29  GLY 29  270 270 GLY GLY P . n 
C 3 30  LEU 30  271 ?   ?   ?   P . n 
C 3 31  ARG 31  272 ?   ?   ?   P . n 
C 3 32  ASP 32  273 ?   ?   ?   P . n 
C 3 33  ALA 33  274 ?   ?   ?   P . n 
C 3 34  SER 34  275 ?   ?   ?   P . n 
C 3 35  GLY 35  276 ?   ?   ?   P . n 
C 3 36  VAL 36  277 277 VAL VAL P . n 
C 3 37  THR 37  278 278 THR THR P . n 
C 3 38  PHE 38  279 279 PHE PHE P . n 
C 3 39  THR 39  280 280 THR THR P . n 
C 3 40  TRP 40  281 281 TRP TRP P . n 
C 3 41  THR 41  282 282 THR THR P . n 
C 3 42  PRO 42  283 283 PRO PRO P . n 
C 3 43  SER 43  284 284 SER SER P . n 
C 3 44  SER 44  285 285 SER SER P . n 
C 3 45  GLY 45  286 286 GLY GLY P . n 
C 3 46  LYS 46  287 287 LYS LYS P . n 
C 3 47  SER 47  288 288 SER SER P . n 
C 3 48  ALA 48  289 289 ALA ALA P . n 
C 3 49  VAL 49  290 290 VAL VAL P . n 
C 3 50  GLN 50  291 291 GLN GLN P . n 
C 3 51  GLY 51  292 292 GLY GLY P . n 
C 3 52  PRO 52  293 293 PRO PRO P . n 
C 3 53  PRO 53  294 294 PRO PRO P . n 
C 3 54  GLU 54  295 295 GLU GLU P . n 
C 3 55  ARG 55  296 ?   ?   ?   P . n 
C 3 56  ASP 56  297 ?   ?   ?   P . n 
C 3 57  LEU 57  298 ?   ?   ?   P . n 
C 3 58  CYS 58  299 299 CYS CYS P . n 
C 3 59  GLY 59  300 300 GLY GLY P . n 
C 3 60  CYS 60  301 301 CYS CYS P . n 
C 3 61  TYR 61  302 302 TYR TYR P . n 
C 3 62  SER 62  303 303 SER SER P . n 
C 3 63  VAL 63  304 304 VAL VAL P . n 
C 3 64  SER 64  305 305 SER SER P . n 
C 3 65  SER 65  306 306 SER SER P . n 
C 3 66  VAL 66  307 307 VAL VAL P . n 
C 3 67  LEU 67  308 308 LEU LEU P . n 
C 3 68  PRO 68  309 309 PRO PRO P . n 
C 3 69  GLY 69  310 310 GLY GLY P . n 
C 3 70  CYS 70  311 311 CYS CYS P . n 
C 3 71  ALA 71  312 312 ALA ALA P . n 
C 3 72  GLU 72  313 313 GLU GLU P . n 
C 3 73  PRO 73  314 314 PRO PRO P . n 
C 3 74  TRP 74  315 315 TRP TRP P . n 
C 3 75  ASN 75  316 316 ASN ASN P . n 
C 3 76  HIS 76  317 317 HIS HIS P . n 
C 3 77  GLY 77  318 318 GLY GLY P . n 
C 3 78  LYS 78  319 319 LYS LYS P . n 
C 3 79  THR 79  320 320 THR THR P . n 
C 3 80  PHE 80  321 321 PHE PHE P . n 
C 3 81  THR 81  322 322 THR THR P . n 
C 3 82  CYS 82  323 323 CYS CYS P . n 
C 3 83  THR 83  324 324 THR THR P . n 
C 3 84  ALA 84  325 325 ALA ALA P . n 
C 3 85  ALA 85  326 326 ALA ALA P . n 
C 3 86  TYR 86  327 327 TYR TYR P . n 
C 3 87  PRO 87  328 328 PRO PRO P . n 
C 3 88  GLU 88  329 329 GLU GLU P . n 
C 3 89  SER 89  330 330 SER SER P . n 
C 3 90  LYS 90  331 331 LYS LYS P . n 
C 3 91  THR 91  332 332 THR THR P . n 
C 3 92  PRO 92  333 333 PRO PRO P . n 
C 3 93  LEU 93  334 334 LEU LEU P . n 
C 3 94  THR 94  335 335 THR THR P . n 
C 3 95  ALA 95  336 336 ALA ALA P . n 
C 3 96  THR 96  337 337 THR THR P . n 
C 3 97  LEU 97  338 338 LEU LEU P . n 
C 3 98  SER 98  339 339 SER SER P . n 
C 3 99  LYS 99  340 340 LYS LYS P . n 
C 3 100 SER 100 341 341 SER SER P . n 
C 3 101 GLY 101 342 342 GLY GLY P . n 
C 3 102 ASN 102 343 343 ASN ASN P . n 
C 3 103 THR 103 344 344 THR THR P . n 
C 3 104 PHE 104 345 345 PHE PHE P . n 
C 3 105 ARG 105 346 346 ARG ARG P . n 
C 3 106 PRO 106 347 347 PRO PRO P . n 
C 3 107 GLU 107 348 348 GLU GLU P . n 
C 3 108 VAL 108 349 349 VAL VAL P . n 
C 3 109 HIS 109 350 350 HIS HIS P . n 
C 3 110 LEU 110 351 351 LEU LEU P . n 
C 3 111 LEU 111 352 352 LEU LEU P . n 
C 3 112 PRO 112 353 353 PRO PRO P . n 
C 3 113 PRO 113 354 354 PRO PRO P . n 
C 3 114 PRO 114 355 355 PRO PRO P . n 
C 3 115 SER 115 356 356 SER SER P . n 
C 3 116 GLU 116 357 357 GLU GLU P . n 
C 3 117 GLU 117 358 358 GLU GLU P . n 
C 3 118 LEU 118 359 359 LEU LEU P . n 
C 3 119 ALA 119 360 360 ALA ALA P . n 
C 3 120 LEU 120 361 361 LEU LEU P . n 
C 3 121 ASN 121 362 362 ASN ASN P . n 
C 3 122 GLU 122 363 363 GLU GLU P . n 
C 3 123 LEU 123 364 364 LEU LEU P . n 
C 3 124 VAL 124 365 365 VAL VAL P . n 
C 3 125 THR 125 366 366 THR THR P . n 
C 3 126 LEU 126 367 367 LEU LEU P . n 
C 3 127 THR 127 368 368 THR THR P . n 
C 3 128 CYS 128 369 369 CYS CYS P . n 
C 3 129 LEU 129 370 370 LEU LEU P . n 
C 3 130 ALA 130 371 371 ALA ALA P . n 
C 3 131 ARG 131 372 372 ARG ARG P . n 
C 3 132 GLY 132 373 373 GLY GLY P . n 
C 3 133 PHE 133 374 374 PHE PHE P . n 
C 3 134 SER 134 375 375 SER SER P . n 
C 3 135 PRO 135 376 376 PRO PRO P . n 
C 3 136 LYS 136 377 377 LYS LYS P . n 
C 3 137 ASP 137 378 378 ASP ASP P . n 
C 3 138 VAL 138 379 379 VAL VAL P . n 
C 3 139 LEU 139 380 380 LEU LEU P . n 
C 3 140 VAL 140 381 381 VAL VAL P . n 
C 3 141 ARG 141 382 382 ARG ARG P . n 
C 3 142 TRP 142 383 383 TRP TRP P . n 
C 3 143 LEU 143 384 384 LEU LEU P . n 
C 3 144 GLN 144 385 385 GLN GLN P . n 
C 3 145 GLY 145 386 386 GLY GLY P . n 
C 3 146 SER 146 387 387 SER SER P . n 
C 3 147 GLN 147 388 388 GLN GLN P . n 
C 3 148 GLU 148 389 389 GLU GLU P . n 
C 3 149 LEU 149 390 390 LEU LEU P . n 
C 3 150 PRO 150 391 391 PRO PRO P . n 
C 3 151 ARG 151 392 392 ARG ARG P . n 
C 3 152 GLU 152 393 393 GLU GLU P . n 
C 3 153 LYS 153 394 394 LYS LYS P . n 
C 3 154 TYR 154 395 395 TYR TYR P . n 
C 3 155 LEU 155 396 396 LEU LEU P . n 
C 3 156 THR 156 397 397 THR THR P . n 
C 3 157 TRP 157 398 398 TRP TRP P . n 
C 3 158 ALA 158 399 399 ALA ALA P . n 
C 3 159 SER 159 400 400 SER SER P . n 
C 3 160 ARG 160 401 401 ARG ARG P . n 
C 3 161 GLN 161 402 402 GLN GLN P . n 
C 3 162 GLU 162 403 403 GLU GLU P . n 
C 3 163 PRO 163 404 404 PRO PRO P . n 
C 3 164 SER 164 405 405 SER SER P . n 
C 3 165 GLN 165 406 406 GLN GLN P . n 
C 3 166 GLY 166 407 407 GLY GLY P . n 
C 3 167 THR 167 408 408 THR THR P . n 
C 3 168 THR 168 409 409 THR THR P . n 
C 3 169 THR 169 410 410 THR THR P . n 
C 3 170 PHE 170 411 411 PHE PHE P . n 
C 3 171 ALA 171 412 412 ALA ALA P . n 
C 3 172 VAL 172 413 413 VAL VAL P . n 
C 3 173 THR 173 414 414 THR THR P . n 
C 3 174 SER 174 415 415 SER SER P . n 
C 3 175 ILE 175 416 416 ILE ILE P . n 
C 3 176 LEU 176 417 417 LEU LEU P . n 
C 3 177 ARG 177 418 418 ARG ARG P . n 
C 3 178 VAL 178 419 419 VAL VAL P . n 
C 3 179 ALA 179 420 420 ALA ALA P . n 
C 3 180 ALA 180 421 421 ALA ALA P . n 
C 3 181 GLU 181 422 422 GLU GLU P . n 
C 3 182 ASP 182 423 423 ASP ASP P . n 
C 3 183 TRP 183 424 424 TRP TRP P . n 
C 3 184 LYS 184 425 425 LYS LYS P . n 
C 3 185 LYS 185 426 426 LYS LYS P . n 
C 3 186 GLY 186 427 427 GLY GLY P . n 
C 3 187 ASP 187 428 428 ASP ASP P . n 
C 3 188 THR 188 429 429 THR THR P . n 
C 3 189 PHE 189 430 430 PHE PHE P . n 
C 3 190 SER 190 431 431 SER SER P . n 
C 3 191 CYS 191 432 432 CYS CYS P . n 
C 3 192 MET 192 433 433 MET MET P . n 
C 3 193 VAL 193 434 434 VAL VAL P . n 
C 3 194 GLY 194 435 435 GLY GLY P . n 
C 3 195 HIS 195 436 436 HIS HIS P . n 
C 3 196 GLU 196 437 437 GLU GLU P . n 
C 3 197 ALA 197 438 438 ALA ALA P . n 
C 3 198 LEU 198 439 439 LEU LEU P . n 
C 3 199 PRO 199 440 440 PRO PRO P . n 
C 3 200 LEU 200 441 441 LEU LEU P . n 
C 3 201 ALA 201 442 442 ALA ALA P . n 
C 3 202 PHE 202 443 443 PHE PHE P . n 
C 3 203 THR 203 444 444 THR THR P . n 
C 3 204 GLN 204 445 445 GLN GLN P . n 
C 3 205 LYS 205 446 446 LYS LYS P . n 
C 3 206 THR 206 447 447 THR THR P . n 
C 3 207 ILE 207 448 448 ILE ILE P . n 
C 3 208 ASP 208 449 449 ASP ASP P . n 
C 3 209 ARG 209 450 450 ARG ARG P . n 
C 3 210 LEU 210 451 451 LEU LEU P . n 
C 3 211 ALA 211 452 452 ALA ALA P . n 
C 3 212 GLY 212 453 ?   ?   ?   P . n 
C 3 213 LYS 213 454 ?   ?   ?   P . n 
D 3 1   CYS 1   242 242 CYS CYS Q . n 
D 3 2   HIS 2   243 243 HIS HIS Q . n 
D 3 3   PRO 3   244 244 PRO PRO Q . n 
D 3 4   ARG 4   245 245 ARG ARG Q . n 
D 3 5   LEU 5   246 246 LEU LEU Q . n 
D 3 6   SER 6   247 247 SER SER Q . n 
D 3 7   LEU 7   248 248 LEU LEU Q . n 
D 3 8   HIS 8   249 249 HIS HIS Q . n 
D 3 9   ARG 9   250 250 ARG ARG Q . n 
D 3 10  PRO 10  251 251 PRO PRO Q . n 
D 3 11  ALA 11  252 252 ALA ALA Q . n 
D 3 12  LEU 12  253 253 LEU LEU Q . n 
D 3 13  GLU 13  254 254 GLU GLU Q . n 
D 3 14  ASP 14  255 255 ASP ASP Q . n 
D 3 15  LEU 15  256 256 LEU LEU Q . n 
D 3 16  LEU 16  257 257 LEU LEU Q . n 
D 3 17  LEU 17  258 258 LEU LEU Q . n 
D 3 18  GLY 18  259 259 GLY GLY Q . n 
D 3 19  SER 19  260 260 SER SER Q . n 
D 3 20  GLU 20  261 261 GLU GLU Q . n 
D 3 21  ALA 21  262 262 ALA ALA Q . n 
D 3 22  ASN 22  263 263 ASN ASN Q . n 
D 3 23  LEU 23  264 264 LEU LEU Q . n 
D 3 24  THR 24  265 265 THR THR Q . n 
D 3 25  CYS 25  266 266 CYS CYS Q . n 
D 3 26  THR 26  267 267 THR THR Q . n 
D 3 27  LEU 27  268 268 LEU LEU Q . n 
D 3 28  THR 28  269 269 THR THR Q . n 
D 3 29  GLY 29  270 270 GLY GLY Q . n 
D 3 30  LEU 30  271 ?   ?   ?   Q . n 
D 3 31  ARG 31  272 ?   ?   ?   Q . n 
D 3 32  ASP 32  273 273 ASP ASP Q . n 
D 3 33  ALA 33  274 274 ALA ALA Q . n 
D 3 34  SER 34  275 275 SER SER Q . n 
D 3 35  GLY 35  276 276 GLY GLY Q . n 
D 3 36  VAL 36  277 277 VAL VAL Q . n 
D 3 37  THR 37  278 278 THR THR Q . n 
D 3 38  PHE 38  279 279 PHE PHE Q . n 
D 3 39  THR 39  280 280 THR THR Q . n 
D 3 40  TRP 40  281 281 TRP TRP Q . n 
D 3 41  THR 41  282 282 THR THR Q . n 
D 3 42  PRO 42  283 283 PRO PRO Q . n 
D 3 43  SER 43  284 284 SER SER Q . n 
D 3 44  SER 44  285 285 SER SER Q . n 
D 3 45  GLY 45  286 286 GLY GLY Q . n 
D 3 46  LYS 46  287 287 LYS LYS Q . n 
D 3 47  SER 47  288 288 SER SER Q . n 
D 3 48  ALA 48  289 289 ALA ALA Q . n 
D 3 49  VAL 49  290 290 VAL VAL Q . n 
D 3 50  GLN 50  291 291 GLN GLN Q . n 
D 3 51  GLY 51  292 292 GLY GLY Q . n 
D 3 52  PRO 52  293 293 PRO PRO Q . n 
D 3 53  PRO 53  294 294 PRO PRO Q . n 
D 3 54  GLU 54  295 295 GLU GLU Q . n 
D 3 55  ARG 55  296 296 ARG ARG Q . n 
D 3 56  ASP 56  297 ?   ?   ?   Q . n 
D 3 57  LEU 57  298 ?   ?   ?   Q . n 
D 3 58  CYS 58  299 ?   ?   ?   Q . n 
D 3 59  GLY 59  300 300 GLY GLY Q . n 
D 3 60  CYS 60  301 301 CYS CYS Q . n 
D 3 61  TYR 61  302 302 TYR TYR Q . n 
D 3 62  SER 62  303 303 SER SER Q . n 
D 3 63  VAL 63  304 304 VAL VAL Q . n 
D 3 64  SER 64  305 305 SER SER Q . n 
D 3 65  SER 65  306 306 SER SER Q . n 
D 3 66  VAL 66  307 307 VAL VAL Q . n 
D 3 67  LEU 67  308 308 LEU LEU Q . n 
D 3 68  PRO 68  309 309 PRO PRO Q . n 
D 3 69  GLY 69  310 310 GLY GLY Q . n 
D 3 70  CYS 70  311 311 CYS CYS Q . n 
D 3 71  ALA 71  312 312 ALA ALA Q . n 
D 3 72  GLU 72  313 313 GLU GLU Q . n 
D 3 73  PRO 73  314 314 PRO PRO Q . n 
D 3 74  TRP 74  315 315 TRP TRP Q . n 
D 3 75  ASN 75  316 316 ASN ASN Q . n 
D 3 76  HIS 76  317 317 HIS HIS Q . n 
D 3 77  GLY 77  318 318 GLY GLY Q . n 
D 3 78  LYS 78  319 319 LYS LYS Q . n 
D 3 79  THR 79  320 320 THR THR Q . n 
D 3 80  PHE 80  321 321 PHE PHE Q . n 
D 3 81  THR 81  322 322 THR THR Q . n 
D 3 82  CYS 82  323 323 CYS CYS Q . n 
D 3 83  THR 83  324 324 THR THR Q . n 
D 3 84  ALA 84  325 325 ALA ALA Q . n 
D 3 85  ALA 85  326 326 ALA ALA Q . n 
D 3 86  TYR 86  327 327 TYR TYR Q . n 
D 3 87  PRO 87  328 328 PRO PRO Q . n 
D 3 88  GLU 88  329 329 GLU GLU Q . n 
D 3 89  SER 89  330 330 SER SER Q . n 
D 3 90  LYS 90  331 331 LYS LYS Q . n 
D 3 91  THR 91  332 332 THR THR Q . n 
D 3 92  PRO 92  333 333 PRO PRO Q . n 
D 3 93  LEU 93  334 334 LEU LEU Q . n 
D 3 94  THR 94  335 335 THR THR Q . n 
D 3 95  ALA 95  336 336 ALA ALA Q . n 
D 3 96  THR 96  337 337 THR THR Q . n 
D 3 97  LEU 97  338 338 LEU LEU Q . n 
D 3 98  SER 98  339 339 SER SER Q . n 
D 3 99  LYS 99  340 340 LYS LYS Q . n 
D 3 100 SER 100 341 341 SER SER Q . n 
D 3 101 GLY 101 342 342 GLY GLY Q . n 
D 3 102 ASN 102 343 343 ASN ASN Q . n 
D 3 103 THR 103 344 344 THR THR Q . n 
D 3 104 PHE 104 345 345 PHE PHE Q . n 
D 3 105 ARG 105 346 346 ARG ARG Q . n 
D 3 106 PRO 106 347 347 PRO PRO Q . n 
D 3 107 GLU 107 348 348 GLU GLU Q . n 
D 3 108 VAL 108 349 349 VAL VAL Q . n 
D 3 109 HIS 109 350 350 HIS HIS Q . n 
D 3 110 LEU 110 351 351 LEU LEU Q . n 
D 3 111 LEU 111 352 352 LEU LEU Q . n 
D 3 112 PRO 112 353 353 PRO PRO Q . n 
D 3 113 PRO 113 354 354 PRO PRO Q . n 
D 3 114 PRO 114 355 355 PRO PRO Q . n 
D 3 115 SER 115 356 356 SER SER Q . n 
D 3 116 GLU 116 357 357 GLU GLU Q . n 
D 3 117 GLU 117 358 358 GLU GLU Q . n 
D 3 118 LEU 118 359 359 LEU LEU Q . n 
D 3 119 ALA 119 360 360 ALA ALA Q . n 
D 3 120 LEU 120 361 361 LEU LEU Q . n 
D 3 121 ASN 121 362 362 ASN ASN Q . n 
D 3 122 GLU 122 363 363 GLU GLU Q . n 
D 3 123 LEU 123 364 364 LEU LEU Q . n 
D 3 124 VAL 124 365 365 VAL VAL Q . n 
D 3 125 THR 125 366 366 THR THR Q . n 
D 3 126 LEU 126 367 367 LEU LEU Q . n 
D 3 127 THR 127 368 368 THR THR Q . n 
D 3 128 CYS 128 369 369 CYS CYS Q . n 
D 3 129 LEU 129 370 370 LEU LEU Q . n 
D 3 130 ALA 130 371 371 ALA ALA Q . n 
D 3 131 ARG 131 372 372 ARG ARG Q . n 
D 3 132 GLY 132 373 373 GLY GLY Q . n 
D 3 133 PHE 133 374 374 PHE PHE Q . n 
D 3 134 SER 134 375 375 SER SER Q . n 
D 3 135 PRO 135 376 376 PRO PRO Q . n 
D 3 136 LYS 136 377 377 LYS LYS Q . n 
D 3 137 ASP 137 378 378 ASP ASP Q . n 
D 3 138 VAL 138 379 379 VAL VAL Q . n 
D 3 139 LEU 139 380 380 LEU LEU Q . n 
D 3 140 VAL 140 381 381 VAL VAL Q . n 
D 3 141 ARG 141 382 382 ARG ARG Q . n 
D 3 142 TRP 142 383 383 TRP TRP Q . n 
D 3 143 LEU 143 384 384 LEU LEU Q . n 
D 3 144 GLN 144 385 385 GLN GLN Q . n 
D 3 145 GLY 145 386 386 GLY GLY Q . n 
D 3 146 SER 146 387 387 SER SER Q . n 
D 3 147 GLN 147 388 388 GLN GLN Q . n 
D 3 148 GLU 148 389 389 GLU GLU Q . n 
D 3 149 LEU 149 390 390 LEU LEU Q . n 
D 3 150 PRO 150 391 391 PRO PRO Q . n 
D 3 151 ARG 151 392 392 ARG ARG Q . n 
D 3 152 GLU 152 393 393 GLU GLU Q . n 
D 3 153 LYS 153 394 394 LYS LYS Q . n 
D 3 154 TYR 154 395 395 TYR TYR Q . n 
D 3 155 LEU 155 396 396 LEU LEU Q . n 
D 3 156 THR 156 397 397 THR THR Q . n 
D 3 157 TRP 157 398 398 TRP TRP Q . n 
D 3 158 ALA 158 399 399 ALA ALA Q . n 
D 3 159 SER 159 400 400 SER SER Q . n 
D 3 160 ARG 160 401 401 ARG ARG Q . n 
D 3 161 GLN 161 402 402 GLN GLN Q . n 
D 3 162 GLU 162 403 403 GLU GLU Q . n 
D 3 163 PRO 163 404 404 PRO PRO Q . n 
D 3 164 SER 164 405 405 SER SER Q . n 
D 3 165 GLN 165 406 406 GLN GLN Q . n 
D 3 166 GLY 166 407 407 GLY GLY Q . n 
D 3 167 THR 167 408 408 THR THR Q . n 
D 3 168 THR 168 409 409 THR THR Q . n 
D 3 169 THR 169 410 410 THR THR Q . n 
D 3 170 PHE 170 411 411 PHE PHE Q . n 
D 3 171 ALA 171 412 412 ALA ALA Q . n 
D 3 172 VAL 172 413 413 VAL VAL Q . n 
D 3 173 THR 173 414 414 THR THR Q . n 
D 3 174 SER 174 415 415 SER SER Q . n 
D 3 175 ILE 175 416 416 ILE ILE Q . n 
D 3 176 LEU 176 417 417 LEU LEU Q . n 
D 3 177 ARG 177 418 418 ARG ARG Q . n 
D 3 178 VAL 178 419 419 VAL VAL Q . n 
D 3 179 ALA 179 420 420 ALA ALA Q . n 
D 3 180 ALA 180 421 421 ALA ALA Q . n 
D 3 181 GLU 181 422 422 GLU GLU Q . n 
D 3 182 ASP 182 423 423 ASP ASP Q . n 
D 3 183 TRP 183 424 424 TRP TRP Q . n 
D 3 184 LYS 184 425 425 LYS LYS Q . n 
D 3 185 LYS 185 426 426 LYS LYS Q . n 
D 3 186 GLY 186 427 427 GLY GLY Q . n 
D 3 187 ASP 187 428 428 ASP ASP Q . n 
D 3 188 THR 188 429 429 THR THR Q . n 
D 3 189 PHE 189 430 430 PHE PHE Q . n 
D 3 190 SER 190 431 431 SER SER Q . n 
D 3 191 CYS 191 432 432 CYS CYS Q . n 
D 3 192 MET 192 433 433 MET MET Q . n 
D 3 193 VAL 193 434 434 VAL VAL Q . n 
D 3 194 GLY 194 435 435 GLY GLY Q . n 
D 3 195 HIS 195 436 436 HIS HIS Q . n 
D 3 196 GLU 196 437 437 GLU GLU Q . n 
D 3 197 ALA 197 438 438 ALA ALA Q . n 
D 3 198 LEU 198 439 439 LEU LEU Q . n 
D 3 199 PRO 199 440 440 PRO PRO Q . n 
D 3 200 LEU 200 441 441 LEU LEU Q . n 
D 3 201 ALA 201 442 442 ALA ALA Q . n 
D 3 202 PHE 202 443 443 PHE PHE Q . n 
D 3 203 THR 203 444 444 THR THR Q . n 
D 3 204 GLN 204 445 445 GLN GLN Q . n 
D 3 205 LYS 205 446 446 LYS LYS Q . n 
D 3 206 THR 206 447 447 THR THR Q . n 
D 3 207 ILE 207 448 448 ILE ILE Q . n 
D 3 208 ASP 208 449 449 ASP ASP Q . n 
D 3 209 ARG 209 450 450 ARG ARG Q . n 
D 3 210 LEU 210 451 451 LEU LEU Q . n 
D 3 211 ALA 211 452 452 ALA ALA Q . n 
D 3 212 GLY 212 453 ?   ?   ?   Q . n 
D 3 213 LYS 213 454 ?   ?   ?   Q . n 
E 1 1   MET 1   -17 ?   ?   ?   A . n 
E 1 2   GLY 2   -16 ?   ?   ?   A . n 
E 1 3   TRP 3   -15 ?   ?   ?   A . n 
E 1 4   SER 4   -14 ?   ?   ?   A . n 
E 1 5   CYS 5   -13 ?   ?   ?   A . n 
E 1 6   ILE 6   -12 ?   ?   ?   A . n 
E 1 7   ILE 7   -11 ?   ?   ?   A . n 
E 1 8   LEU 8   -10 ?   ?   ?   A . n 
E 1 9   PHE 9   -9  ?   ?   ?   A . n 
E 1 10  LEU 10  -8  ?   ?   ?   A . n 
E 1 11  VAL 11  -7  ?   ?   ?   A . n 
E 1 12  ALA 12  -6  ?   ?   ?   A . n 
E 1 13  THR 13  -5  ?   ?   ?   A . n 
E 1 14  ALA 14  -4  ?   ?   ?   A . n 
E 1 15  THR 15  -3  ?   ?   ?   A . n 
E 1 16  GLY 16  -2  ?   ?   ?   A . n 
E 1 17  VAL 17  -1  ?   ?   ?   A . n 
E 1 18  HIS 18  0   ?   ?   ?   A . n 
E 1 19  SER 19  1   ?   ?   ?   A . n 
E 1 20  GLU 20  2   2   GLU GLU A . n 
E 1 21  VAL 21  3   3   VAL VAL A . n 
E 1 22  GLN 22  4   4   GLN GLN A . n 
E 1 23  LEU 23  5   5   LEU LEU A . n 
E 1 24  LEU 24  6   6   LEU LEU A . n 
E 1 25  GLU 25  7   7   GLU GLU A . n 
E 1 26  SER 26  8   8   SER SER A . n 
E 1 27  GLY 27  9   9   GLY GLY A . n 
E 1 28  GLY 28  10  10  GLY GLY A . n 
E 1 29  GLY 29  11  11  GLY GLY A . n 
E 1 30  LEU 30  12  12  LEU LEU A . n 
E 1 31  VAL 31  13  13  VAL VAL A . n 
E 1 32  GLN 32  14  14  GLN GLN A . n 
E 1 33  PRO 33  15  15  PRO PRO A . n 
E 1 34  GLY 34  16  16  GLY GLY A . n 
E 1 35  GLY 35  17  17  GLY GLY A . n 
E 1 36  SER 36  18  18  SER SER A . n 
E 1 37  LEU 37  19  19  LEU LEU A . n 
E 1 38  ARG 38  20  20  ARG ARG A . n 
E 1 39  LEU 39  21  21  LEU LEU A . n 
E 1 40  SER 40  22  22  SER SER A . n 
E 1 41  CYS 41  23  23  CYS CYS A . n 
E 1 42  ALA 42  24  24  ALA ALA A . n 
E 1 43  ALA 43  25  25  ALA ALA A . n 
E 1 44  SER 44  26  26  SER SER A . n 
E 1 45  GLY 45  27  27  GLY GLY A . n 
E 1 46  PHE 46  28  28  PHE PHE A . n 
E 1 47  THR 47  29  29  THR THR A . n 
E 1 48  SER 48  30  30  SER SER A . n 
E 1 49  SER 49  31  31  SER SER A . n 
E 1 50  ASN 50  32  32  ASN ASN A . n 
E 1 51  TYR 51  33  33  TYR TYR A . n 
E 1 52  LEU 52  34  34  LEU LEU A . n 
E 1 53  MET 53  35  35  MET MET A . n 
E 1 54  SER 54  36  36  SER SER A . n 
E 1 55  TRP 55  37  37  TRP TRP A . n 
E 1 56  VAL 56  38  38  VAL VAL A . n 
E 1 57  ARG 57  39  39  ARG ARG A . n 
E 1 58  GLN 58  40  40  GLN GLN A . n 
E 1 59  ALA 59  41  41  ALA ALA A . n 
E 1 60  PRO 60  42  42  PRO PRO A . n 
E 1 61  GLY 61  43  43  GLY GLY A . n 
E 1 62  LYS 62  44  44  LYS LYS A . n 
E 1 63  GLY 63  45  45  GLY GLY A . n 
E 1 64  LEU 64  46  46  LEU LEU A . n 
E 1 65  GLU 65  47  47  GLU GLU A . n 
E 1 66  TRP 66  48  48  TRP TRP A . n 
E 1 67  VAL 67  49  49  VAL VAL A . n 
E 1 68  SER 68  50  50  SER SER A . n 
E 1 69  SER 69  51  51  SER SER A . n 
E 1 70  ILE 70  52  52  ILE ILE A . n 
E 1 71  TYR 71  53  53  TYR TYR A . n 
E 1 72  HIS 72  54  54  HIS HIS A . n 
E 1 73  TYR 73  55  55  TYR TYR A . n 
E 1 74  GLY 74  56  56  GLY GLY A . n 
E 1 75  HIS 75  57  57  HIS HIS A . n 
E 1 76  ASN 76  58  58  ASN ASN A . n 
E 1 77  ALA 77  59  59  ALA ALA A . n 
E 1 78  TYR 78  60  60  TYR TYR A . n 
E 1 79  TYR 79  61  61  TYR TYR A . n 
E 1 80  ALA 80  62  62  ALA ALA A . n 
E 1 81  ASP 81  63  63  ASP ASP A . n 
E 1 82  SER 82  64  64  SER SER A . n 
E 1 83  VAL 83  65  65  VAL VAL A . n 
E 1 84  LYS 84  66  66  LYS LYS A . n 
E 1 85  GLY 85  67  67  GLY GLY A . n 
E 1 86  ARG 86  68  68  ARG ARG A . n 
E 1 87  PHE 87  69  69  PHE PHE A . n 
E 1 88  THR 88  70  70  THR THR A . n 
E 1 89  ILE 89  71  71  ILE ILE A . n 
E 1 90  SER 90  72  72  SER SER A . n 
E 1 91  ARG 91  73  73  ARG ARG A . n 
E 1 92  ASP 92  74  74  ASP ASP A . n 
E 1 93  ASN 93  75  75  ASN ASN A . n 
E 1 94  SER 94  76  76  SER SER A . n 
E 1 95  LYS 95  77  77  LYS LYS A . n 
E 1 96  ASN 96  78  78  ASN ASN A . n 
E 1 97  THR 97  79  79  THR THR A . n 
E 1 98  LEU 98  80  80  LEU LEU A . n 
E 1 99  TYR 99  81  81  TYR TYR A . n 
E 1 100 LEU 100 82  82  LEU LEU A . n 
E 1 101 GLN 101 83  83  GLN GLN A . n 
E 1 102 MET 102 84  84  MET MET A . n 
E 1 103 ASN 103 85  85  ASN ASN A . n 
E 1 104 SER 104 86  86  SER SER A . n 
E 1 105 LEU 105 87  87  LEU LEU A . n 
E 1 106 ARG 106 88  88  ARG ARG A . n 
E 1 107 ALA 107 89  89  ALA ALA A . n 
E 1 108 GLU 108 90  90  GLU GLU A . n 
E 1 109 ASP 109 91  91  ASP ASP A . n 
E 1 110 THR 110 92  92  THR THR A . n 
E 1 111 ALA 111 93  93  ALA ALA A . n 
E 1 112 VAL 112 94  94  VAL VAL A . n 
E 1 113 TYR 113 95  95  TYR TYR A . n 
E 1 114 TYR 114 96  96  TYR TYR A . n 
E 1 115 CYS 115 97  97  CYS CYS A . n 
E 1 116 ALA 116 98  98  ALA ALA A . n 
E 1 117 LYS 117 99  99  LYS LYS A . n 
E 1 118 VAL 118 100 100 VAL VAL A . n 
E 1 119 ASP 119 101 101 ASP ASP A . n 
E 1 120 SER 120 102 102 SER SER A . n 
E 1 121 ALA 121 103 103 ALA ALA A . n 
E 1 122 TYR 122 104 104 TYR TYR A . n 
E 1 123 ASP 123 105 105 ASP ASP A . n 
E 1 124 PHE 124 106 106 PHE PHE A . n 
E 1 125 GLY 125 107 107 GLY GLY A . n 
E 1 126 SER 126 108 108 SER SER A . n 
E 1 127 TRP 127 109 109 TRP TRP A . n 
E 1 128 GLY 128 110 110 GLY GLY A . n 
E 1 129 GLN 129 111 111 GLN GLN A . n 
E 1 130 GLY 130 112 112 GLY GLY A . n 
E 1 131 THR 131 113 113 THR THR A . n 
E 1 132 LEU 132 114 114 LEU LEU A . n 
E 1 133 VAL 133 115 115 VAL VAL A . n 
E 1 134 THR 134 116 116 THR THR A . n 
E 1 135 VAL 135 117 117 VAL VAL A . n 
E 1 136 SER 136 118 118 SER SER A . n 
E 1 137 SER 137 119 119 SER SER A . n 
E 1 138 ALA 138 120 120 ALA ALA A . n 
E 1 139 SER 139 121 121 SER SER A . n 
E 1 140 THR 140 122 122 THR THR A . n 
E 1 141 LYS 141 123 123 LYS LYS A . n 
E 1 142 GLY 142 124 124 GLY GLY A . n 
E 1 143 PRO 143 125 125 PRO PRO A . n 
E 1 144 SER 144 126 126 SER SER A . n 
E 1 145 VAL 145 127 127 VAL VAL A . n 
E 1 146 PHE 146 128 128 PHE PHE A . n 
E 1 147 PRO 147 129 129 PRO PRO A . n 
E 1 148 LEU 148 130 130 LEU LEU A . n 
E 1 149 ALA 149 131 131 ALA ALA A . n 
E 1 150 PRO 150 132 132 PRO PRO A . n 
E 1 151 SER 151 133 133 SER SER A . n 
E 1 152 SER 152 134 134 SER SER A . n 
E 1 153 LYS 153 135 135 LYS LYS A . n 
E 1 154 SER 154 136 136 SER SER A . n 
E 1 155 THR 155 137 137 THR THR A . n 
E 1 156 SER 156 138 138 SER SER A . n 
E 1 157 GLY 157 139 139 GLY GLY A . n 
E 1 158 GLY 158 140 140 GLY GLY A . n 
E 1 159 THR 159 141 141 THR THR A . n 
E 1 160 ALA 160 142 142 ALA ALA A . n 
E 1 161 ALA 161 143 143 ALA ALA A . n 
E 1 162 LEU 162 144 144 LEU LEU A . n 
E 1 163 GLY 163 145 145 GLY GLY A . n 
E 1 164 CYS 164 146 146 CYS CYS A . n 
E 1 165 LEU 165 147 147 LEU LEU A . n 
E 1 166 VAL 166 148 148 VAL VAL A . n 
E 1 167 LYS 167 149 149 LYS LYS A . n 
E 1 168 ASP 168 150 150 ASP ASP A . n 
E 1 169 TYR 169 151 151 TYR TYR A . n 
E 1 170 PHE 170 152 152 PHE PHE A . n 
E 1 171 PRO 171 153 153 PRO PRO A . n 
E 1 172 GLU 172 154 154 GLU GLU A . n 
E 1 173 PRO 173 155 155 PRO PRO A . n 
E 1 174 VAL 174 156 156 VAL VAL A . n 
E 1 175 THR 175 157 157 THR THR A . n 
E 1 176 VAL 176 158 158 VAL VAL A . n 
E 1 177 SER 177 159 159 SER SER A . n 
E 1 178 TRP 178 160 160 TRP TRP A . n 
E 1 179 ASN 179 161 161 ASN ASN A . n 
E 1 180 SER 180 162 162 SER SER A . n 
E 1 181 GLY 181 163 163 GLY GLY A . n 
E 1 182 ALA 182 164 164 ALA ALA A . n 
E 1 183 LEU 183 165 165 LEU LEU A . n 
E 1 184 THR 184 166 166 THR THR A . n 
E 1 185 SER 185 167 167 SER SER A . n 
E 1 186 GLY 186 168 168 GLY GLY A . n 
E 1 187 VAL 187 169 169 VAL VAL A . n 
E 1 188 HIS 188 170 170 HIS HIS A . n 
E 1 189 THR 189 171 171 THR THR A . n 
E 1 190 PHE 190 172 172 PHE PHE A . n 
E 1 191 PRO 191 173 173 PRO PRO A . n 
E 1 192 ALA 192 174 174 ALA ALA A . n 
E 1 193 VAL 193 175 175 VAL VAL A . n 
E 1 194 LEU 194 176 176 LEU LEU A . n 
E 1 195 GLN 195 177 177 GLN GLN A . n 
E 1 196 SER 196 178 178 SER SER A . n 
E 1 197 SER 197 179 179 SER SER A . n 
E 1 198 GLY 198 180 180 GLY GLY A . n 
E 1 199 LEU 199 181 181 LEU LEU A . n 
E 1 200 TYR 200 182 182 TYR TYR A . n 
E 1 201 SER 201 183 183 SER SER A . n 
E 1 202 LEU 202 184 184 LEU LEU A . n 
E 1 203 SER 203 185 185 SER SER A . n 
E 1 204 SER 204 186 186 SER SER A . n 
E 1 205 VAL 205 187 187 VAL VAL A . n 
E 1 206 VAL 206 188 188 VAL VAL A . n 
E 1 207 THR 207 189 189 THR THR A . n 
E 1 208 VAL 208 190 190 VAL VAL A . n 
E 1 209 PRO 209 191 191 PRO PRO A . n 
E 1 210 SER 210 192 192 SER SER A . n 
E 1 211 SER 211 193 193 SER SER A . n 
E 1 212 SER 212 194 194 SER SER A . n 
E 1 213 LEU 213 195 195 LEU LEU A . n 
E 1 214 GLY 214 196 196 GLY GLY A . n 
E 1 215 THR 215 197 197 THR THR A . n 
E 1 216 GLN 216 198 198 GLN GLN A . n 
E 1 217 THR 217 199 199 THR THR A . n 
E 1 218 TYR 218 200 200 TYR TYR A . n 
E 1 219 ILE 219 201 201 ILE ILE A . n 
E 1 220 CYS 220 202 202 CYS CYS A . n 
E 1 221 ASN 221 203 203 ASN ASN A . n 
E 1 222 VAL 222 204 204 VAL VAL A . n 
E 1 223 ASN 223 205 205 ASN ASN A . n 
E 1 224 HIS 224 206 206 HIS HIS A . n 
E 1 225 LYS 225 207 207 LYS LYS A . n 
E 1 226 PRO 226 208 208 PRO PRO A . n 
E 1 227 SER 227 209 209 SER SER A . n 
E 1 228 ASN 228 210 210 ASN ASN A . n 
E 1 229 THR 229 211 211 THR THR A . n 
E 1 230 LYS 230 212 212 LYS LYS A . n 
E 1 231 VAL 231 213 213 VAL VAL A . n 
E 1 232 ASP 232 214 214 ASP ASP A . n 
E 1 233 LYS 233 215 215 LYS LYS A . n 
E 1 234 LYS 234 216 216 LYS LYS A . n 
E 1 235 VAL 235 217 217 VAL VAL A . n 
E 1 236 GLU 236 218 218 GLU GLU A . n 
E 1 237 PRO 237 219 219 PRO PRO A . n 
E 1 238 LYS 238 220 220 LYS LYS A . n 
E 1 239 SER 239 221 221 SER SER A . n 
E 1 240 CYS 240 222 222 CYS CYS A . n 
E 1 241 ASP 241 223 223 ASP ASP A . n 
E 1 242 LYS 242 224 224 LYS LYS A . n 
E 1 243 THR 243 225 ?   ?   ?   A . n 
E 1 244 HIS 244 226 ?   ?   ?   A . n 
F 2 1   MET 1   -18 ?   ?   ?   B . n 
F 2 2   GLY 2   -17 ?   ?   ?   B . n 
F 2 3   TRP 3   -16 ?   ?   ?   B . n 
F 2 4   SER 4   -15 ?   ?   ?   B . n 
F 2 5   CYS 5   -14 ?   ?   ?   B . n 
F 2 6   ILE 6   -13 ?   ?   ?   B . n 
F 2 7   ILE 7   -12 ?   ?   ?   B . n 
F 2 8   LEU 8   -11 ?   ?   ?   B . n 
F 2 9   PHE 9   -10 ?   ?   ?   B . n 
F 2 10  LEU 10  -9  ?   ?   ?   B . n 
F 2 11  VAL 11  -8  ?   ?   ?   B . n 
F 2 12  ALA 12  -7  ?   ?   ?   B . n 
F 2 13  THR 13  -6  ?   ?   ?   B . n 
F 2 14  ALA 14  -5  ?   ?   ?   B . n 
F 2 15  THR 15  -4  ?   ?   ?   B . n 
F 2 16  GLY 16  -3  ?   ?   ?   B . n 
F 2 17  VAL 17  -2  ?   ?   ?   B . n 
F 2 18  HIS 18  -1  ?   ?   ?   B . n 
F 2 19  SER 19  0   ?   ?   ?   B . n 
F 2 20  GLN 20  1   ?   ?   ?   B . n 
F 2 21  SER 21  2   2   SER SER B . n 
F 2 22  VAL 22  3   3   VAL VAL B . n 
F 2 23  LEU 23  4   4   LEU LEU B . n 
F 2 24  THR 24  5   5   THR THR B . n 
F 2 25  GLN 25  6   6   GLN GLN B . n 
F 2 26  PRO 26  7   7   PRO PRO B . n 
F 2 27  PRO 27  8   8   PRO PRO B . n 
F 2 28  SER 28  9   9   SER SER B . n 
F 2 29  VAL 29  10  10  VAL VAL B . n 
F 2 30  SER 30  11  11  SER SER B . n 
F 2 31  GLY 31  12  12  GLY GLY B . n 
F 2 32  ALA 32  13  13  ALA ALA B . n 
F 2 33  PRO 33  14  14  PRO PRO B . n 
F 2 34  GLY 34  15  15  GLY GLY B . n 
F 2 35  GLN 35  16  16  GLN GLN B . n 
F 2 36  ARG 36  17  17  ARG ARG B . n 
F 2 37  VAL 37  18  18  VAL VAL B . n 
F 2 38  THR 38  19  19  THR THR B . n 
F 2 39  ILE 39  20  20  ILE ILE B . n 
F 2 40  SER 40  21  21  SER SER B . n 
F 2 41  CYS 41  22  22  CYS CYS B . n 
F 2 42  ALA 42  23  23  ALA ALA B . n 
F 2 43  GLY 43  24  24  GLY GLY B . n 
F 2 44  THR 44  25  25  THR THR B . n 
F 2 45  SER 45  26  26  SER SER B . n 
F 2 46  SER 46  27  27  SER SER B . n 
F 2 47  ASP 47  28  28  ASP ASP B . n 
F 2 48  ILE 48  29  29  ILE ILE B . n 
F 2 49  GLY 49  30  30  GLY GLY B . n 
F 2 50  GLY 50  31  31  GLY GLY B . n 
F 2 51  ARG 51  32  32  ARG ARG B . n 
F 2 52  THR 52  33  33  THR THR B . n 
F 2 53  TYR 53  34  34  TYR TYR B . n 
F 2 54  VAL 54  35  35  VAL VAL B . n 
F 2 55  SER 55  36  36  SER SER B . n 
F 2 56  TRP 56  37  37  TRP TRP B . n 
F 2 57  TYR 57  38  38  TYR TYR B . n 
F 2 58  GLN 58  39  39  GLN GLN B . n 
F 2 59  GLN 59  40  40  GLN GLN B . n 
F 2 60  LEU 60  41  41  LEU LEU B . n 
F 2 61  PRO 61  42  42  PRO PRO B . n 
F 2 62  GLY 62  43  43  GLY GLY B . n 
F 2 63  THR 63  44  44  THR THR B . n 
F 2 64  ALA 64  45  45  ALA ALA B . n 
F 2 65  PRO 65  46  46  PRO PRO B . n 
F 2 66  LYS 66  47  47  LYS LYS B . n 
F 2 67  LEU 67  48  48  LEU LEU B . n 
F 2 68  LEU 68  49  49  LEU LEU B . n 
F 2 69  ILE 69  50  50  ILE ILE B . n 
F 2 70  TYR 70  51  51  TYR TYR B . n 
F 2 71  LYS 71  52  52  LYS LYS B . n 
F 2 72  VAL 72  53  53  VAL VAL B . n 
F 2 73  THR 73  54  54  THR THR B . n 
F 2 74  ILE 74  55  55  ILE ILE B . n 
F 2 75  ARG 75  56  56  ARG ARG B . n 
F 2 76  ALA 76  57  57  ALA ALA B . n 
F 2 77  SER 77  58  58  SER SER B . n 
F 2 78  GLY 78  59  59  GLY GLY B . n 
F 2 79  VAL 79  60  60  VAL VAL B . n 
F 2 80  PRO 80  61  61  PRO PRO B . n 
F 2 81  ASP 81  62  62  ASP ASP B . n 
F 2 82  ARG 82  63  63  ARG ARG B . n 
F 2 83  PHE 83  64  64  PHE PHE B . n 
F 2 84  SER 84  65  65  SER SER B . n 
F 2 85  GLY 85  66  66  GLY GLY B . n 
F 2 86  SER 86  67  67  SER SER B . n 
F 2 87  LYS 87  68  68  LYS LYS B . n 
F 2 88  SER 88  69  69  SER SER B . n 
F 2 89  GLY 89  70  70  GLY GLY B . n 
F 2 90  THR 90  71  71  THR THR B . n 
F 2 91  SER 91  72  72  SER SER B . n 
F 2 92  ALA 92  73  73  ALA ALA B . n 
F 2 93  SER 93  74  74  SER SER B . n 
F 2 94  LEU 94  75  75  LEU LEU B . n 
F 2 95  ALA 95  76  76  ALA ALA B . n 
F 2 96  ILE 96  77  77  ILE ILE B . n 
F 2 97  THR 97  78  78  THR THR B . n 
F 2 98  GLY 98  79  79  GLY GLY B . n 
F 2 99  LEU 99  80  80  LEU LEU B . n 
F 2 100 GLN 100 81  81  GLN GLN B . n 
F 2 101 ALA 101 82  82  ALA ALA B . n 
F 2 102 GLU 102 83  83  GLU GLU B . n 
F 2 103 ASP 103 84  84  ASP ASP B . n 
F 2 104 GLU 104 85  85  GLU GLU B . n 
F 2 105 ALA 105 86  86  ALA ALA B . n 
F 2 106 ASP 106 87  87  ASP ASP B . n 
F 2 107 TYR 107 88  88  TYR TYR B . n 
F 2 108 TYR 108 89  89  TYR TYR B . n 
F 2 109 CYS 109 90  90  CYS CYS B . n 
F 2 110 ALA 110 91  91  ALA ALA B . n 
F 2 111 SER 111 92  92  SER SER B . n 
F 2 112 HIS 112 93  93  HIS HIS B . n 
F 2 113 ARG 113 94  94  ARG ARG B . n 
F 2 114 SER 114 95  95  SER SER B . n 
F 2 115 ASN 115 96  96  ASN ASN B . n 
F 2 116 ASN 116 97  97  ASN ASN B . n 
F 2 117 ASN 117 98  98  ASN ASN B . n 
F 2 118 ILE 118 99  99  ILE ILE B . n 
F 2 119 VAL 119 100 100 VAL VAL B . n 
F 2 120 PHE 120 101 101 PHE PHE B . n 
F 2 121 GLY 121 102 102 GLY GLY B . n 
F 2 122 GLY 122 103 103 GLY GLY B . n 
F 2 123 GLY 123 104 104 GLY GLY B . n 
F 2 124 THR 124 105 105 THR THR B . n 
F 2 125 LYS 125 106 106 LYS LYS B . n 
F 2 126 LEU 126 107 107 LEU LEU B . n 
F 2 127 THR 127 108 108 THR THR B . n 
F 2 128 VAL 128 109 109 VAL VAL B . n 
F 2 129 LEU 129 110 110 LEU LEU B . n 
F 2 130 GLY 130 111 111 GLY GLY B . n 
F 2 131 GLN 131 112 112 GLN GLN B . n 
F 2 132 PRO 132 113 113 PRO PRO B . n 
F 2 133 LYS 133 114 114 LYS LYS B . n 
F 2 134 ALA 134 115 115 ALA ALA B . n 
F 2 135 ALA 135 116 116 ALA ALA B . n 
F 2 136 PRO 136 117 117 PRO PRO B . n 
F 2 137 SER 137 118 118 SER SER B . n 
F 2 138 VAL 138 119 119 VAL VAL B . n 
F 2 139 THR 139 120 120 THR THR B . n 
F 2 140 LEU 140 121 121 LEU LEU B . n 
F 2 141 PHE 141 122 122 PHE PHE B . n 
F 2 142 PRO 142 123 123 PRO PRO B . n 
F 2 143 PRO 143 124 124 PRO PRO B . n 
F 2 144 SER 144 125 125 SER SER B . n 
F 2 145 SER 145 126 126 SER SER B . n 
F 2 146 GLU 146 127 127 GLU GLU B . n 
F 2 147 GLU 147 128 128 GLU GLU B . n 
F 2 148 LEU 148 129 129 LEU LEU B . n 
F 2 149 GLN 149 130 130 GLN GLN B . n 
F 2 150 ALA 150 131 131 ALA ALA B . n 
F 2 151 ASN 151 132 132 ASN ASN B . n 
F 2 152 LYS 152 133 133 LYS LYS B . n 
F 2 153 ALA 153 134 134 ALA ALA B . n 
F 2 154 THR 154 135 135 THR THR B . n 
F 2 155 LEU 155 136 136 LEU LEU B . n 
F 2 156 VAL 156 137 137 VAL VAL B . n 
F 2 157 CYS 157 138 138 CYS CYS B . n 
F 2 158 LEU 158 139 139 LEU LEU B . n 
F 2 159 ILE 159 140 140 ILE ILE B . n 
F 2 160 SER 160 141 141 SER SER B . n 
F 2 161 ASP 161 142 142 ASP ASP B . n 
F 2 162 PHE 162 143 143 PHE PHE B . n 
F 2 163 TYR 163 144 144 TYR TYR B . n 
F 2 164 PRO 164 145 145 PRO PRO B . n 
F 2 165 GLY 165 146 146 GLY GLY B . n 
F 2 166 ALA 166 147 147 ALA ALA B . n 
F 2 167 VAL 167 148 148 VAL VAL B . n 
F 2 168 THR 168 149 149 THR THR B . n 
F 2 169 VAL 169 150 150 VAL VAL B . n 
F 2 170 ALA 170 151 151 ALA ALA B . n 
F 2 171 TRP 171 152 152 TRP TRP B . n 
F 2 172 LYS 172 153 153 LYS LYS B . n 
F 2 173 ALA 173 154 154 ALA ALA B . n 
F 2 174 ASP 174 155 155 ASP ASP B . n 
F 2 175 SER 175 156 156 SER SER B . n 
F 2 176 SER 176 157 157 SER SER B . n 
F 2 177 PRO 177 158 158 PRO PRO B . n 
F 2 178 VAL 178 159 159 VAL VAL B . n 
F 2 179 LYS 179 160 160 LYS LYS B . n 
F 2 180 ALA 180 161 161 ALA ALA B . n 
F 2 181 GLY 181 162 162 GLY GLY B . n 
F 2 182 VAL 182 163 163 VAL VAL B . n 
F 2 183 GLU 183 164 164 GLU GLU B . n 
F 2 184 THR 184 165 165 THR THR B . n 
F 2 185 THR 185 166 166 THR THR B . n 
F 2 186 THR 186 167 167 THR THR B . n 
F 2 187 PRO 187 168 168 PRO PRO B . n 
F 2 188 SER 188 169 169 SER SER B . n 
F 2 189 LYS 189 170 170 LYS LYS B . n 
F 2 190 GLN 190 171 171 GLN GLN B . n 
F 2 191 SER 191 172 172 SER SER B . n 
F 2 192 ASN 192 173 173 ASN ASN B . n 
F 2 193 ASN 193 174 174 ASN ASN B . n 
F 2 194 LYS 194 175 175 LYS LYS B . n 
F 2 195 TYR 195 176 176 TYR TYR B . n 
F 2 196 ALA 196 177 177 ALA ALA B . n 
F 2 197 ALA 197 178 178 ALA ALA B . n 
F 2 198 SER 198 179 179 SER SER B . n 
F 2 199 SER 199 180 180 SER SER B . n 
F 2 200 TYR 200 181 181 TYR TYR B . n 
F 2 201 LEU 201 182 182 LEU LEU B . n 
F 2 202 SER 202 183 183 SER SER B . n 
F 2 203 LEU 203 184 184 LEU LEU B . n 
F 2 204 THR 204 185 185 THR THR B . n 
F 2 205 PRO 205 186 186 PRO PRO B . n 
F 2 206 GLU 206 187 187 GLU GLU B . n 
F 2 207 GLN 207 188 188 GLN GLN B . n 
F 2 208 TRP 208 189 189 TRP TRP B . n 
F 2 209 LYS 209 190 190 LYS LYS B . n 
F 2 210 SER 210 191 191 SER SER B . n 
F 2 211 HIS 211 192 192 HIS HIS B . n 
F 2 212 ARG 212 193 193 ARG ARG B . n 
F 2 213 SER 213 194 194 SER SER B . n 
F 2 214 TYR 214 195 195 TYR TYR B . n 
F 2 215 SER 215 196 196 SER SER B . n 
F 2 216 CYS 216 197 197 CYS CYS B . n 
F 2 217 GLN 217 198 198 GLN GLN B . n 
F 2 218 VAL 218 199 199 VAL VAL B . n 
F 2 219 THR 219 200 200 THR THR B . n 
F 2 220 HIS 220 201 201 HIS HIS B . n 
F 2 221 GLU 221 202 202 GLU GLU B . n 
F 2 222 GLY 222 203 203 GLY GLY B . n 
F 2 223 SER 223 204 204 SER SER B . n 
F 2 224 THR 224 205 205 THR THR B . n 
F 2 225 VAL 225 206 206 VAL VAL B . n 
F 2 226 GLU 226 207 207 GLU GLU B . n 
F 2 227 LYS 227 208 208 LYS LYS B . n 
F 2 228 THR 228 209 209 THR THR B . n 
F 2 229 VAL 229 210 210 VAL VAL B . n 
F 2 230 ALA 230 211 211 ALA ALA B . n 
F 2 231 PRO 231 212 212 PRO PRO B . n 
F 2 232 THR 232 213 213 THR THR B . n 
F 2 233 GLU 233 214 214 GLU GLU B . n 
F 2 234 CYS 234 215 215 CYS CYS B . n 
F 2 235 SER 235 216 ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 4 EDO 1  301 1   EDO EDO H . 
H 4 EDO 1  302 2   EDO EDO H . 
I 5 PEG 1  303 3   PEG PEG H . 
J 5 PEG 1  301 10  PEG PEG L . 
K 6 MG  1  302 16  MG  MG  L . 
L 6 MG  1  501 17  MG  MG  P . 
M 5 PEG 1  301 4   PEG PEG A . 
N 4 EDO 1  302 9   EDO EDO A . 
O 5 PEG 1  303 11  PEG PEG A . 
P 5 PEG 1  304 12  PEG PEG A . 
Q 4 EDO 1  305 13  EDO EDO A . 
R 6 MG  1  301 18  MG  MG  B . 
S 7 HOH 1  401 385 HOH HOH H . 
S 7 HOH 2  402 173 HOH HOH H . 
S 7 HOH 3  403 395 HOH HOH H . 
S 7 HOH 4  404 29  HOH HOH H . 
S 7 HOH 5  405 174 HOH HOH H . 
S 7 HOH 6  406 187 HOH HOH H . 
S 7 HOH 7  407 102 HOH HOH H . 
S 7 HOH 8  408 171 HOH HOH H . 
S 7 HOH 9  409 67  HOH HOH H . 
S 7 HOH 10 410 115 HOH HOH H . 
S 7 HOH 11 411 228 HOH HOH H . 
S 7 HOH 12 412 436 HOH HOH H . 
S 7 HOH 13 413 73  HOH HOH H . 
S 7 HOH 14 414 159 HOH HOH H . 
S 7 HOH 15 415 156 HOH HOH H . 
S 7 HOH 16 416 248 HOH HOH H . 
S 7 HOH 17 417 100 HOH HOH H . 
S 7 HOH 18 418 108 HOH HOH H . 
S 7 HOH 19 419 388 HOH HOH H . 
S 7 HOH 20 420 358 HOH HOH H . 
S 7 HOH 21 421 47  HOH HOH H . 
S 7 HOH 22 422 332 HOH HOH H . 
S 7 HOH 23 423 105 HOH HOH H . 
S 7 HOH 24 424 219 HOH HOH H . 
S 7 HOH 25 425 280 HOH HOH H . 
S 7 HOH 26 426 313 HOH HOH H . 
S 7 HOH 27 427 133 HOH HOH H . 
S 7 HOH 28 428 76  HOH HOH H . 
S 7 HOH 29 429 24  HOH HOH H . 
S 7 HOH 30 430 95  HOH HOH H . 
S 7 HOH 31 431 391 HOH HOH H . 
S 7 HOH 32 432 151 HOH HOH H . 
S 7 HOH 33 433 272 HOH HOH H . 
S 7 HOH 34 434 170 HOH HOH H . 
S 7 HOH 35 435 81  HOH HOH H . 
S 7 HOH 36 436 249 HOH HOH H . 
S 7 HOH 37 437 65  HOH HOH H . 
S 7 HOH 38 438 214 HOH HOH H . 
S 7 HOH 39 439 87  HOH HOH H . 
S 7 HOH 40 440 88  HOH HOH H . 
S 7 HOH 41 441 19  HOH HOH H . 
S 7 HOH 42 442 69  HOH HOH H . 
S 7 HOH 43 443 251 HOH HOH H . 
S 7 HOH 44 444 44  HOH HOH H . 
S 7 HOH 45 445 389 HOH HOH H . 
S 7 HOH 46 446 158 HOH HOH H . 
S 7 HOH 47 447 397 HOH HOH H . 
S 7 HOH 48 448 188 HOH HOH H . 
S 7 HOH 49 449 36  HOH HOH H . 
S 7 HOH 50 450 335 HOH HOH H . 
S 7 HOH 51 451 137 HOH HOH H . 
S 7 HOH 52 452 383 HOH HOH H . 
S 7 HOH 53 453 186 HOH HOH H . 
S 7 HOH 54 454 161 HOH HOH H . 
S 7 HOH 55 455 435 HOH HOH H . 
S 7 HOH 56 456 365 HOH HOH H . 
S 7 HOH 57 457 359 HOH HOH H . 
S 7 HOH 58 458 330 HOH HOH H . 
S 7 HOH 59 459 150 HOH HOH H . 
S 7 HOH 60 460 250 HOH HOH H . 
S 7 HOH 61 461 312 HOH HOH H . 
S 7 HOH 62 462 206 HOH HOH H . 
S 7 HOH 63 463 176 HOH HOH H . 
S 7 HOH 64 464 152 HOH HOH H . 
S 7 HOH 65 465 153 HOH HOH H . 
S 7 HOH 66 466 107 HOH HOH H . 
S 7 HOH 67 467 147 HOH HOH H . 
S 7 HOH 68 468 392 HOH HOH H . 
S 7 HOH 69 469 386 HOH HOH H . 
S 7 HOH 70 470 390 HOH HOH H . 
S 7 HOH 71 471 420 HOH HOH H . 
S 7 HOH 72 472 154 HOH HOH H . 
S 7 HOH 73 473 394 HOH HOH H . 
T 7 HOH 1  401 387 HOH HOH L . 
T 7 HOH 2  402 406 HOH HOH L . 
T 7 HOH 3  403 276 HOH HOH L . 
T 7 HOH 4  404 177 HOH HOH L . 
T 7 HOH 5  405 444 HOH HOH L . 
T 7 HOH 6  406 241 HOH HOH L . 
T 7 HOH 7  407 238 HOH HOH L . 
T 7 HOH 8  408 368 HOH HOH L . 
T 7 HOH 9  409 373 HOH HOH L . 
T 7 HOH 10 410 246 HOH HOH L . 
T 7 HOH 11 411 167 HOH HOH L . 
T 7 HOH 12 412 403 HOH HOH L . 
T 7 HOH 13 413 99  HOH HOH L . 
T 7 HOH 14 414 229 HOH HOH L . 
T 7 HOH 15 415 16  HOH HOH L . 
T 7 HOH 16 416 172 HOH HOH L . 
T 7 HOH 17 417 200 HOH HOH L . 
T 7 HOH 18 418 233 HOH HOH L . 
T 7 HOH 19 419 90  HOH HOH L . 
T 7 HOH 20 420 326 HOH HOH L . 
T 7 HOH 21 421 117 HOH HOH L . 
T 7 HOH 22 422 72  HOH HOH L . 
T 7 HOH 23 423 15  HOH HOH L . 
T 7 HOH 24 424 91  HOH HOH L . 
T 7 HOH 25 425 360 HOH HOH L . 
T 7 HOH 26 426 236 HOH HOH L . 
T 7 HOH 27 427 182 HOH HOH L . 
T 7 HOH 28 428 277 HOH HOH L . 
T 7 HOH 29 429 17  HOH HOH L . 
T 7 HOH 30 430 146 HOH HOH L . 
T 7 HOH 31 431 175 HOH HOH L . 
T 7 HOH 32 432 68  HOH HOH L . 
T 7 HOH 33 433 86  HOH HOH L . 
T 7 HOH 34 434 232 HOH HOH L . 
T 7 HOH 35 435 119 HOH HOH L . 
T 7 HOH 36 436 112 HOH HOH L . 
T 7 HOH 37 437 209 HOH HOH L . 
T 7 HOH 38 438 437 HOH HOH L . 
T 7 HOH 39 439 324 HOH HOH L . 
T 7 HOH 40 440 204 HOH HOH L . 
T 7 HOH 41 441 230 HOH HOH L . 
T 7 HOH 42 442 183 HOH HOH L . 
T 7 HOH 43 443 366 HOH HOH L . 
T 7 HOH 44 444 135 HOH HOH L . 
T 7 HOH 45 445 71  HOH HOH L . 
T 7 HOH 46 446 11  HOH HOH L . 
T 7 HOH 47 447 181 HOH HOH L . 
T 7 HOH 48 448 281 HOH HOH L . 
T 7 HOH 49 449 252 HOH HOH L . 
T 7 HOH 50 450 165 HOH HOH L . 
T 7 HOH 51 451 2   HOH HOH L . 
T 7 HOH 52 452 7   HOH HOH L . 
T 7 HOH 53 453 45  HOH HOH L . 
T 7 HOH 54 454 407 HOH HOH L . 
T 7 HOH 55 455 55  HOH HOH L . 
T 7 HOH 56 456 198 HOH HOH L . 
T 7 HOH 57 457 184 HOH HOH L . 
T 7 HOH 58 458 12  HOH HOH L . 
T 7 HOH 59 459 21  HOH HOH L . 
T 7 HOH 60 460 320 HOH HOH L . 
T 7 HOH 61 461 202 HOH HOH L . 
T 7 HOH 62 462 54  HOH HOH L . 
T 7 HOH 63 463 445 HOH HOH L . 
T 7 HOH 64 464 6   HOH HOH L . 
T 7 HOH 65 465 217 HOH HOH L . 
T 7 HOH 66 466 426 HOH HOH L . 
T 7 HOH 67 467 42  HOH HOH L . 
T 7 HOH 68 468 331 HOH HOH L . 
T 7 HOH 69 469 23  HOH HOH L . 
T 7 HOH 70 470 446 HOH HOH L . 
T 7 HOH 71 471 148 HOH HOH L . 
T 7 HOH 72 472 401 HOH HOH L . 
T 7 HOH 73 473 245 HOH HOH L . 
T 7 HOH 74 474 322 HOH HOH L . 
T 7 HOH 75 475 404 HOH HOH L . 
T 7 HOH 76 476 191 HOH HOH L . 
T 7 HOH 77 477 447 HOH HOH L . 
T 7 HOH 78 478 429 HOH HOH L . 
T 7 HOH 79 479 393 HOH HOH L . 
T 7 HOH 80 480 163 HOH HOH L . 
T 7 HOH 81 481 400 HOH HOH L . 
T 7 HOH 82 482 237 HOH HOH L . 
T 7 HOH 83 483 140 HOH HOH L . 
T 7 HOH 84 484 369 HOH HOH L . 
T 7 HOH 85 485 162 HOH HOH L . 
T 7 HOH 86 486 438 HOH HOH L . 
T 7 HOH 87 487 240 HOH HOH L . 
T 7 HOH 88 488 398 HOH HOH L . 
T 7 HOH 89 489 405 HOH HOH L . 
T 7 HOH 90 490 244 HOH HOH L . 
T 7 HOH 91 491 239 HOH HOH L . 
T 7 HOH 92 492 185 HOH HOH L . 
T 7 HOH 93 493 234 HOH HOH L . 
T 7 HOH 94 494 247 HOH HOH L . 
T 7 HOH 95 495 432 HOH HOH L . 
T 7 HOH 96 496 235 HOH HOH L . 
T 7 HOH 97 497 231 HOH HOH L . 
U 7 HOH 1  601 255 HOH HOH P . 
U 7 HOH 2  602 422 HOH HOH P . 
U 7 HOH 3  603 267 HOH HOH P . 
U 7 HOH 4  604 374 HOH HOH P . 
U 7 HOH 5  605 164 HOH HOH P . 
U 7 HOH 6  606 168 HOH HOH P . 
U 7 HOH 7  607 257 HOH HOH P . 
U 7 HOH 8  608 196 HOH HOH P . 
U 7 HOH 9  609 253 HOH HOH P . 
U 7 HOH 10 610 375 HOH HOH P . 
U 7 HOH 11 611 351 HOH HOH P . 
U 7 HOH 12 612 37  HOH HOH P . 
U 7 HOH 13 613 85  HOH HOH P . 
U 7 HOH 14 614 28  HOH HOH P . 
U 7 HOH 15 615 337 HOH HOH P . 
U 7 HOH 16 616 271 HOH HOH P . 
U 7 HOH 17 617 32  HOH HOH P . 
U 7 HOH 18 618 127 HOH HOH P . 
U 7 HOH 19 619 318 HOH HOH P . 
U 7 HOH 20 620 34  HOH HOH P . 
U 7 HOH 21 621 412 HOH HOH P . 
U 7 HOH 22 622 443 HOH HOH P . 
U 7 HOH 23 623 22  HOH HOH P . 
U 7 HOH 24 624 402 HOH HOH P . 
U 7 HOH 25 625 279 HOH HOH P . 
U 7 HOH 26 626 46  HOH HOH P . 
U 7 HOH 27 627 82  HOH HOH P . 
U 7 HOH 28 628 103 HOH HOH P . 
U 7 HOH 29 629 361 HOH HOH P . 
U 7 HOH 30 630 269 HOH HOH P . 
U 7 HOH 31 631 439 HOH HOH P . 
U 7 HOH 32 632 169 HOH HOH P . 
U 7 HOH 33 633 413 HOH HOH P . 
V 7 HOH 1  501 284 HOH HOH Q . 
V 7 HOH 2  502 268 HOH HOH Q . 
V 7 HOH 3  503 349 HOH HOH Q . 
V 7 HOH 4  504 434 HOH HOH Q . 
V 7 HOH 5  505 260 HOH HOH Q . 
V 7 HOH 6  506 372 HOH HOH Q . 
V 7 HOH 7  507 258 HOH HOH Q . 
V 7 HOH 8  508 270 HOH HOH Q . 
V 7 HOH 9  509 256 HOH HOH Q . 
V 7 HOH 10 510 352 HOH HOH Q . 
V 7 HOH 11 511 278 HOH HOH Q . 
V 7 HOH 12 512 48  HOH HOH Q . 
V 7 HOH 13 513 442 HOH HOH Q . 
V 7 HOH 14 514 227 HOH HOH Q . 
V 7 HOH 15 515 300 HOH HOH Q . 
V 7 HOH 16 516 419 HOH HOH Q . 
V 7 HOH 17 517 31  HOH HOH Q . 
V 7 HOH 18 518 129 HOH HOH Q . 
V 7 HOH 19 519 317 HOH HOH Q . 
V 7 HOH 20 520 66  HOH HOH Q . 
V 7 HOH 21 521 52  HOH HOH Q . 
V 7 HOH 22 522 424 HOH HOH Q . 
V 7 HOH 23 523 328 HOH HOH Q . 
V 7 HOH 24 524 348 HOH HOH Q . 
V 7 HOH 25 525 356 HOH HOH Q . 
V 7 HOH 26 526 114 HOH HOH Q . 
V 7 HOH 27 527 199 HOH HOH Q . 
V 7 HOH 28 528 353 HOH HOH Q . 
V 7 HOH 29 529 282 HOH HOH Q . 
V 7 HOH 30 530 63  HOH HOH Q . 
V 7 HOH 31 531 262 HOH HOH Q . 
V 7 HOH 32 532 201 HOH HOH Q . 
V 7 HOH 33 533 440 HOH HOH Q . 
V 7 HOH 34 534 350 HOH HOH Q . 
V 7 HOH 35 535 259 HOH HOH Q . 
V 7 HOH 36 536 265 HOH HOH Q . 
V 7 HOH 37 537 261 HOH HOH Q . 
V 7 HOH 38 538 441 HOH HOH Q . 
V 7 HOH 39 539 266 HOH HOH Q . 
W 7 HOH 1  401 289 HOH HOH A . 
W 7 HOH 2  402 286 HOH HOH A . 
W 7 HOH 3  403 288 HOH HOH A . 
W 7 HOH 4  404 70  HOH HOH A . 
W 7 HOH 5  405 377 HOH HOH A . 
W 7 HOH 6  406 319 HOH HOH A . 
W 7 HOH 7  407 93  HOH HOH A . 
W 7 HOH 8  408 20  HOH HOH A . 
W 7 HOH 9  409 311 HOH HOH A . 
W 7 HOH 10 410 292 HOH HOH A . 
W 7 HOH 11 411 124 HOH HOH A . 
W 7 HOH 12 412 354 HOH HOH A . 
W 7 HOH 13 413 298 HOH HOH A . 
W 7 HOH 14 414 60  HOH HOH A . 
W 7 HOH 15 415 295 HOH HOH A . 
W 7 HOH 16 416 376 HOH HOH A . 
W 7 HOH 17 417 101 HOH HOH A . 
W 7 HOH 18 418 79  HOH HOH A . 
W 7 HOH 19 419 50  HOH HOH A . 
W 7 HOH 20 420 104 HOH HOH A . 
W 7 HOH 21 421 290 HOH HOH A . 
W 7 HOH 22 422 380 HOH HOH A . 
W 7 HOH 23 423 327 HOH HOH A . 
W 7 HOH 24 424 27  HOH HOH A . 
W 7 HOH 25 425 3   HOH HOH A . 
W 7 HOH 26 426 25  HOH HOH A . 
W 7 HOH 27 427 299 HOH HOH A . 
W 7 HOH 28 428 75  HOH HOH A . 
W 7 HOH 29 429 30  HOH HOH A . 
W 7 HOH 30 430 203 HOH HOH A . 
W 7 HOH 31 431 194 HOH HOH A . 
W 7 HOH 32 432 296 HOH HOH A . 
W 7 HOH 33 433 302 HOH HOH A . 
W 7 HOH 34 434 89  HOH HOH A . 
W 7 HOH 35 435 59  HOH HOH A . 
W 7 HOH 36 436 35  HOH HOH A . 
W 7 HOH 37 437 74  HOH HOH A . 
W 7 HOH 38 438 58  HOH HOH A . 
W 7 HOH 39 439 128 HOH HOH A . 
W 7 HOH 40 440 364 HOH HOH A . 
W 7 HOH 41 441 362 HOH HOH A . 
W 7 HOH 42 442 40  HOH HOH A . 
W 7 HOH 43 443 51  HOH HOH A . 
W 7 HOH 44 444 423 HOH HOH A . 
W 7 HOH 45 445 130 HOH HOH A . 
W 7 HOH 46 446 355 HOH HOH A . 
W 7 HOH 47 447 5   HOH HOH A . 
W 7 HOH 48 448 197 HOH HOH A . 
W 7 HOH 49 449 297 HOH HOH A . 
W 7 HOH 50 450 195 HOH HOH A . 
W 7 HOH 51 451 323 HOH HOH A . 
W 7 HOH 52 452 316 HOH HOH A . 
W 7 HOH 53 453 287 HOH HOH A . 
W 7 HOH 54 454 57  HOH HOH A . 
W 7 HOH 55 455 213 HOH HOH A . 
W 7 HOH 56 456 378 HOH HOH A . 
W 7 HOH 57 457 379 HOH HOH A . 
W 7 HOH 58 458 425 HOH HOH A . 
W 7 HOH 59 459 291 HOH HOH A . 
W 7 HOH 60 460 310 HOH HOH A . 
W 7 HOH 61 461 38  HOH HOH A . 
X 7 HOH 1  401 382 HOH HOH B . 
X 7 HOH 2  402 263 HOH HOH B . 
X 7 HOH 3  403 344 HOH HOH B . 
X 7 HOH 4  404 145 HOH HOH B . 
X 7 HOH 5  405 339 HOH HOH B . 
X 7 HOH 6  406 345 HOH HOH B . 
X 7 HOH 7  407 346 HOH HOH B . 
X 7 HOH 8  408 142 HOH HOH B . 
X 7 HOH 9  409 218 HOH HOH B . 
X 7 HOH 10 410 211 HOH HOH B . 
X 7 HOH 11 411 342 HOH HOH B . 
X 7 HOH 12 412 225 HOH HOH B . 
X 7 HOH 13 413 416 HOH HOH B . 
X 7 HOH 14 414 301 HOH HOH B . 
X 7 HOH 15 415 418 HOH HOH B . 
X 7 HOH 16 416 131 HOH HOH B . 
X 7 HOH 17 417 371 HOH HOH B . 
X 7 HOH 18 418 341 HOH HOH B . 
X 7 HOH 19 419 303 HOH HOH B . 
X 7 HOH 20 420 293 HOH HOH B . 
X 7 HOH 21 421 120 HOH HOH B . 
X 7 HOH 22 422 223 HOH HOH B . 
X 7 HOH 23 423 125 HOH HOH B . 
X 7 HOH 24 424 33  HOH HOH B . 
X 7 HOH 25 425 305 HOH HOH B . 
X 7 HOH 26 426 64  HOH HOH B . 
X 7 HOH 27 427 208 HOH HOH B . 
X 7 HOH 28 428 113 HOH HOH B . 
X 7 HOH 29 429 43  HOH HOH B . 
X 7 HOH 30 430 415 HOH HOH B . 
X 7 HOH 31 431 381 HOH HOH B . 
X 7 HOH 32 432 321 HOH HOH B . 
X 7 HOH 33 433 329 HOH HOH B . 
X 7 HOH 34 434 308 HOH HOH B . 
X 7 HOH 35 435 121 HOH HOH B . 
X 7 HOH 36 436 109 HOH HOH B . 
X 7 HOH 37 437 141 HOH HOH B . 
X 7 HOH 38 438 62  HOH HOH B . 
X 7 HOH 39 439 18  HOH HOH B . 
X 7 HOH 40 440 283 HOH HOH B . 
X 7 HOH 41 441 136 HOH HOH B . 
X 7 HOH 42 442 110 HOH HOH B . 
X 7 HOH 43 443 370 HOH HOH B . 
X 7 HOH 44 444 215 HOH HOH B . 
X 7 HOH 45 445 61  HOH HOH B . 
X 7 HOH 46 446 13  HOH HOH B . 
X 7 HOH 47 447 205 HOH HOH B . 
X 7 HOH 48 448 78  HOH HOH B . 
X 7 HOH 49 449 427 HOH HOH B . 
X 7 HOH 50 450 49  HOH HOH B . 
X 7 HOH 51 451 325 HOH HOH B . 
X 7 HOH 52 452 4   HOH HOH B . 
X 7 HOH 53 453 417 HOH HOH B . 
X 7 HOH 54 454 336 HOH HOH B . 
X 7 HOH 55 455 334 HOH HOH B . 
X 7 HOH 56 456 273 HOH HOH B . 
X 7 HOH 57 457 275 HOH HOH B . 
X 7 HOH 58 458 221 HOH HOH B . 
X 7 HOH 59 459 338 HOH HOH B . 
X 7 HOH 60 460 207 HOH HOH B . 
X 7 HOH 61 461 433 HOH HOH B . 
X 7 HOH 62 462 421 HOH HOH B . 
X 7 HOH 63 463 343 HOH HOH B . 
X 7 HOH 64 464 14  HOH HOH B . 
X 7 HOH 65 465 53  HOH HOH B . 
X 7 HOH 66 466 8   HOH HOH B . 
X 7 HOH 67 467 26  HOH HOH B . 
X 7 HOH 68 468 430 HOH HOH B . 
X 7 HOH 69 469 363 HOH HOH B . 
X 7 HOH 70 470 340 HOH HOH B . 
X 7 HOH 71 471 224 HOH HOH B . 
X 7 HOH 72 472 306 HOH HOH B . 
X 7 HOH 73 473 304 HOH HOH B . 
X 7 HOH 74 474 414 HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 0 H LYS 44  ? NZ  ? A LYS 62  NZ  
2   1 Y 0 H SER 50  ? OG  ? A SER 68  OG  
3   1 Y 0 H LYS 66  ? CE  ? A LYS 84  CE  
4   1 Y 0 H LYS 66  ? NZ  ? A LYS 84  NZ  
5   1 Y 0 H LYS 135 ? CG  ? A LYS 153 CG  
6   1 Y 0 H LYS 135 ? CD  ? A LYS 153 CD  
7   1 Y 0 H LYS 135 ? CE  ? A LYS 153 CE  
8   1 Y 0 H LYS 135 ? NZ  ? A LYS 153 NZ  
9   1 Y 0 H SER 136 ? OG  ? A SER 154 OG  
10  1 Y 0 H SER 138 ? OG  ? A SER 156 OG  
11  1 Y 0 H ILE 201 ? CD1 ? A ILE 219 CD1 
12  1 Y 0 H LYS 212 ? NZ  ? A LYS 230 NZ  
13  1 Y 0 H LYS 224 ? CD  ? A LYS 242 CD  
14  1 Y 0 H LYS 224 ? CE  ? A LYS 242 CE  
15  1 Y 0 H LYS 224 ? NZ  ? A LYS 242 NZ  
16  1 Y 0 L LYS 47  ? CE  ? B LYS 66  CE  
17  1 Y 0 L LYS 47  ? NZ  ? B LYS 66  NZ  
18  1 Y 0 L LYS 160 ? NZ  ? B LYS 179 NZ  
19  1 Y 0 P GLU 261 ? CG  ? C GLU 20  CG  
20  1 Y 0 P GLU 261 ? CD  ? C GLU 20  CD  
21  1 Y 0 P GLU 261 ? OE1 ? C GLU 20  OE1 
22  1 Y 0 P GLU 261 ? OE2 ? C GLU 20  OE2 
23  1 Y 0 P LEU 264 ? CD1 ? C LEU 23  CD1 
24  1 Y 0 P LEU 264 ? CD2 ? C LEU 23  CD2 
25  1 Y 0 P LEU 268 ? CD1 ? C LEU 27  CD1 
26  1 Y 0 P LEU 268 ? CD2 ? C LEU 27  CD2 
27  1 Y 0 P THR 269 ? OG1 ? C THR 28  OG1 
28  1 Y 0 P THR 269 ? CG2 ? C THR 28  CG2 
29  1 Y 0 P VAL 277 ? CG1 ? C VAL 36  CG1 
30  1 Y 0 P VAL 277 ? CG2 ? C VAL 36  CG2 
31  1 Y 0 P SER 285 ? OG  ? C SER 44  OG  
32  1 Y 0 P LYS 287 ? CG  ? C LYS 46  CG  
33  1 Y 0 P LYS 287 ? CD  ? C LYS 46  CD  
34  1 Y 0 P LYS 287 ? CE  ? C LYS 46  CE  
35  1 Y 0 P LYS 287 ? NZ  ? C LYS 46  NZ  
36  1 Y 0 P GLU 295 ? CG  ? C GLU 54  CG  
37  1 Y 0 P GLU 295 ? CD  ? C GLU 54  CD  
38  1 Y 0 P GLU 295 ? OE1 ? C GLU 54  OE1 
39  1 Y 0 P GLU 295 ? OE2 ? C GLU 54  OE2 
40  1 Y 0 P TYR 302 ? CG  ? C TYR 61  CG  
41  1 Y 0 P TYR 302 ? CD1 ? C TYR 61  CD1 
42  1 Y 0 P TYR 302 ? CD2 ? C TYR 61  CD2 
43  1 Y 0 P TYR 302 ? CE1 ? C TYR 61  CE1 
44  1 Y 0 P TYR 302 ? CE2 ? C TYR 61  CE2 
45  1 Y 0 P TYR 302 ? CZ  ? C TYR 61  CZ  
46  1 Y 0 P TYR 302 ? OH  ? C TYR 61  OH  
47  1 Y 0 P SER 305 ? OG  ? C SER 64  OG  
48  1 Y 0 P LYS 319 ? CE  ? C LYS 78  CE  
49  1 Y 0 P LYS 319 ? NZ  ? C LYS 78  NZ  
50  1 Y 0 P LYS 331 ? CD  ? C LYS 90  CD  
51  1 Y 0 P LYS 331 ? CE  ? C LYS 90  CE  
52  1 Y 0 P LYS 331 ? NZ  ? C LYS 90  NZ  
53  1 Y 0 P ASN 343 ? CG  ? C ASN 102 CG  
54  1 Y 0 P ASN 343 ? OD1 ? C ASN 102 OD1 
55  1 Y 0 P ASN 343 ? ND2 ? C ASN 102 ND2 
56  1 Y 0 P ARG 392 ? CD  ? C ARG 151 CD  
57  1 Y 0 P ARG 392 ? NE  ? C ARG 151 NE  
58  1 Y 0 P ARG 392 ? CZ  ? C ARG 151 CZ  
59  1 Y 0 P ARG 392 ? NH1 ? C ARG 151 NH1 
60  1 Y 0 P ARG 392 ? NH2 ? C ARG 151 NH2 
61  1 Y 0 P GLN 406 ? CD  ? C GLN 165 CD  
62  1 Y 0 P GLN 406 ? OE1 ? C GLN 165 OE1 
63  1 Y 0 P GLN 406 ? NE2 ? C GLN 165 NE2 
64  1 Y 0 P ILE 416 ? CD1 ? C ILE 175 CD1 
65  1 Y 0 P LYS 425 ? NZ  ? C LYS 184 NZ  
66  1 Y 0 P ARG 450 ? CZ  ? C ARG 209 CZ  
67  1 Y 0 P ARG 450 ? NH1 ? C ARG 209 NH1 
68  1 Y 0 P ARG 450 ? NH2 ? C ARG 209 NH2 
69  1 Y 0 Q CYS 242 ? SG  ? D CYS 1   SG  
70  1 Y 0 Q ARG 245 ? NE  ? D ARG 4   NE  
71  1 Y 0 Q ARG 245 ? CZ  ? D ARG 4   CZ  
72  1 Y 0 Q ARG 245 ? NH1 ? D ARG 4   NH1 
73  1 Y 0 Q ARG 245 ? NH2 ? D ARG 4   NH2 
74  1 Y 0 Q LEU 248 ? CD1 ? D LEU 7   CD1 
75  1 Y 0 Q LEU 248 ? CD2 ? D LEU 7   CD2 
76  1 Y 0 Q GLU 261 ? CG  ? D GLU 20  CG  
77  1 Y 0 Q GLU 261 ? CD  ? D GLU 20  CD  
78  1 Y 0 Q GLU 261 ? OE1 ? D GLU 20  OE1 
79  1 Y 0 Q GLU 261 ? OE2 ? D GLU 20  OE2 
80  1 Y 0 Q THR 267 ? OG1 ? D THR 26  OG1 
81  1 Y 0 Q THR 267 ? CG2 ? D THR 26  CG2 
82  1 Y 0 Q LEU 268 ? CD1 ? D LEU 27  CD1 
83  1 Y 0 Q LEU 268 ? CD2 ? D LEU 27  CD2 
84  1 Y 0 Q THR 269 ? OG1 ? D THR 28  OG1 
85  1 Y 0 Q THR 269 ? CG2 ? D THR 28  CG2 
86  1 Y 0 Q VAL 277 ? CG1 ? D VAL 36  CG1 
87  1 Y 0 Q VAL 277 ? CG2 ? D VAL 36  CG2 
88  1 Y 0 Q THR 278 ? OG1 ? D THR 37  OG1 
89  1 Y 0 Q THR 278 ? CG2 ? D THR 37  CG2 
90  1 Y 0 Q SER 285 ? OG  ? D SER 44  OG  
91  1 Y 0 Q LYS 287 ? CD  ? D LYS 46  CD  
92  1 Y 0 Q LYS 287 ? CE  ? D LYS 46  CE  
93  1 Y 0 Q LYS 287 ? NZ  ? D LYS 46  NZ  
94  1 Y 0 Q SER 288 ? OG  ? D SER 47  OG  
95  1 Y 0 Q GLN 291 ? CD  ? D GLN 50  CD  
96  1 Y 0 Q GLN 291 ? OE1 ? D GLN 50  OE1 
97  1 Y 0 Q GLN 291 ? NE2 ? D GLN 50  NE2 
98  1 Y 0 Q GLU 295 ? CG  ? D GLU 54  CG  
99  1 Y 0 Q GLU 295 ? CD  ? D GLU 54  CD  
100 1 Y 0 Q GLU 295 ? OE1 ? D GLU 54  OE1 
101 1 Y 0 Q GLU 295 ? OE2 ? D GLU 54  OE2 
102 1 Y 0 Q ARG 296 ? CD  ? D ARG 55  CD  
103 1 Y 0 Q ARG 296 ? NE  ? D ARG 55  NE  
104 1 Y 0 Q ARG 296 ? CZ  ? D ARG 55  CZ  
105 1 Y 0 Q ARG 296 ? NH1 ? D ARG 55  NH1 
106 1 Y 0 Q ARG 296 ? NH2 ? D ARG 55  NH2 
107 1 Y 0 Q TYR 302 ? CG  ? D TYR 61  CG  
108 1 Y 0 Q TYR 302 ? CD1 ? D TYR 61  CD1 
109 1 Y 0 Q TYR 302 ? CD2 ? D TYR 61  CD2 
110 1 Y 0 Q TYR 302 ? CE1 ? D TYR 61  CE1 
111 1 Y 0 Q TYR 302 ? CE2 ? D TYR 61  CE2 
112 1 Y 0 Q TYR 302 ? CZ  ? D TYR 61  CZ  
113 1 Y 0 Q TYR 302 ? OH  ? D TYR 61  OH  
114 1 Y 0 Q SER 305 ? OG  ? D SER 64  OG  
115 1 Y 0 Q LYS 319 ? CD  ? D LYS 78  CD  
116 1 Y 0 Q LYS 319 ? CE  ? D LYS 78  CE  
117 1 Y 0 Q LYS 319 ? NZ  ? D LYS 78  NZ  
118 1 Y 0 Q LYS 331 ? CD  ? D LYS 90  CD  
119 1 Y 0 Q LYS 331 ? CE  ? D LYS 90  CE  
120 1 Y 0 Q LYS 331 ? NZ  ? D LYS 90  NZ  
121 1 Y 0 Q ASN 343 ? CG  ? D ASN 102 CG  
122 1 Y 0 Q ASN 343 ? OD1 ? D ASN 102 OD1 
123 1 Y 0 Q ASN 343 ? ND2 ? D ASN 102 ND2 
124 1 Y 0 Q LYS 377 ? NZ  ? D LYS 136 NZ  
125 1 Y 0 Q ARG 392 ? NE  ? D ARG 151 NE  
126 1 Y 0 Q ARG 392 ? CZ  ? D ARG 151 CZ  
127 1 Y 0 Q ARG 392 ? NH1 ? D ARG 151 NH1 
128 1 Y 0 Q ARG 392 ? NH2 ? D ARG 151 NH2 
129 1 Y 0 Q GLN 406 ? CD  ? D GLN 165 CD  
130 1 Y 0 Q GLN 406 ? OE1 ? D GLN 165 OE1 
131 1 Y 0 Q GLN 406 ? NE2 ? D GLN 165 NE2 
132 1 Y 0 Q LYS 425 ? CD  ? D LYS 184 CD  
133 1 Y 0 Q LYS 425 ? CE  ? D LYS 184 CE  
134 1 Y 0 Q LYS 425 ? NZ  ? D LYS 184 NZ  
135 1 Y 0 Q ILE 448 ? CD1 ? D ILE 207 CD1 
136 1 Y 0 Q LEU 451 ? CD1 ? D LEU 210 CD1 
137 1 Y 0 Q LEU 451 ? CD2 ? D LEU 210 CD2 
138 1 Y 0 A LYS 66  ? CE  ? E LYS 84  CE  
139 1 Y 0 A LYS 66  ? NZ  ? E LYS 84  NZ  
140 1 Y 0 A LYS 77  ? NZ  ? E LYS 95  NZ  
141 1 Y 0 A GLN 111 ? CD  ? E GLN 129 CD  
142 1 Y 0 A GLN 111 ? OE1 ? E GLN 129 OE1 
143 1 Y 0 A GLN 111 ? NE2 ? E GLN 129 NE2 
144 1 Y 0 A LYS 135 ? CD  ? E LYS 153 CD  
145 1 Y 0 A LYS 135 ? CE  ? E LYS 153 CE  
146 1 Y 0 A LYS 135 ? NZ  ? E LYS 153 NZ  
147 1 Y 0 A THR 137 ? OG1 ? E THR 155 OG1 
148 1 Y 0 A THR 137 ? CG2 ? E THR 155 CG2 
149 1 Y 0 A LYS 212 ? CE  ? E LYS 230 CE  
150 1 Y 0 A LYS 212 ? NZ  ? E LYS 230 NZ  
151 1 Y 0 A LYS 224 ? CD  ? E LYS 242 CD  
152 1 Y 0 A LYS 224 ? CE  ? E LYS 242 CE  
153 1 Y 0 A LYS 224 ? NZ  ? E LYS 242 NZ  
154 1 Y 0 B ILE 99  ? CD1 ? F ILE 118 CD1 
155 1 Y 0 B LYS 106 ? CE  ? F LYS 125 CE  
156 1 Y 0 B LYS 106 ? NZ  ? F LYS 125 NZ  
157 1 Y 0 B LYS 160 ? NZ  ? F LYS 179 NZ  
158 1 Y 0 B ARG 193 ? NE  ? F ARG 212 NE  
159 1 Y 0 B ARG 193 ? CZ  ? F ARG 212 CZ  
160 1 Y 0 B ARG 193 ? NH1 ? F ARG 212 NH1 
161 1 Y 0 B ARG 193 ? NH2 ? F ARG 212 NH2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_reference_DOI 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0267       ? 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .              ? 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS      ? ? ? 'Jun 30, 2023' ? 3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? 1.1.7          ? 4 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless  ? ? ? 0.7.13         ? 5 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .              ? 6 
# 
_cell.angle_alpha                  90 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.35 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9R2E 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     77.291 
_cell.length_a_esd                 ? 
_cell.length_b                     232.312 
_cell.length_b_esd                 ? 
_cell.length_c                     105.519 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9R2E 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9R2E 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.21 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          61.68 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;16% (w/v) PEG8000, 20% (v/v) Glycerol, 0.16 M MgAcetate, 0.08 M Na
Cacodylate pH 6.50
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 X CdTe 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-01-20 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.885603 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE ID23-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.885603 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ID23-1 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9R2E 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.539 
_reflns.d_resolution_low                               116.16 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     59436 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           97.2 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          4.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.129 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                0.129 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.539 
_reflns_shell.d_res_low                                     2.583 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.3 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3039 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               2.8 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.7 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.592 
_reflns_shell.pdbx_Rsym_value                               1.592 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.69 
_refine.aniso_B[1][2]                            0 
_refine.aniso_B[1][3]                            -0.13 
_refine.aniso_B[2][2]                            -0.9 
_refine.aniso_B[2][3]                            0 
_refine.aniso_B[3][3]                            1.59 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               53.97 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.936 
_refine.correlation_coeff_Fo_to_Fc_free          0.916 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9R2E 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.54 
_refine.ls_d_res_low                             116.16 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     55813 
_refine.ls_number_reflns_R_free                  2937 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    96.1 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.21306 
_refine.ls_R_factor_R_free                       0.25182 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.21095 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.54 
_refine_hist.d_res_low                        116.16 
_refine_hist.number_atoms_solvent             377 
_refine_hist.number_atoms_total               10042 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        9611 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         54 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
_refine_ls_shell.pdbx_refine_id                      'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                          2.54 
_refine_ls_shell.d_res_low                           2.583 
_refine_ls_shell.number_reflns_all                   ? 
_refine_ls_shell.number_reflns_obs                   ? 
_refine_ls_shell.number_reflns_R_free                ? 
_refine_ls_shell.number_reflns_R_work                ? 
_refine_ls_shell.percent_reflns_obs                  89.26 
_refine_ls_shell.percent_reflns_R_free               ? 
_refine_ls_shell.R_factor_all                        ? 
_refine_ls_shell.R_factor_obs                        ? 
_refine_ls_shell.R_factor_R_free_error               ? 
_refine_ls_shell.R_factor_R_work                     0.328 
_refine_ls_shell.redundancy_reflns_all               ? 
_refine_ls_shell.redundancy_reflns_obs               ? 
_refine_ls_shell.wR_factor_all                       ? 
_refine_ls_shell.wR_factor_obs                       ? 
_refine_ls_shell.wR_factor_R_free                    ? 
_refine_ls_shell.wR_factor_R_work                    ? 
_refine_ls_shell.pdbx_R_complete                     ? 
_refine_ls_shell.correlation_coeff_Fo_to_Fc          ? 
_refine_ls_shell.correlation_coeff_Fo_to_Fc_free     ? 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_work   ? 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_free   ? 
_refine_ls_shell.pdbx_total_number_of_bins_used      ? 
_refine_ls_shell.pdbx_phase_error                    ? 
_refine_ls_shell.pdbx_fsc_work                       ? 
_refine_ls_shell.pdbx_fsc_free                       ? 
_refine_ls_shell.R_factor_R_free                     0.338 
# 
_struct.entry_id                     9R2E 
_struct.title                        'Structure of ARGX-121 Fab fragment in complex with the Fc fragment of IgA1' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9R2E 
_struct_keywords.text            'Antibody, immune system, IgA mediated autoimmunity, immunoglobulin, PROTEROS BIOSTRUCTURES GMBH' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 1 ? 
F N N 2 ? 
G N N 4 ? 
H N N 4 ? 
I N N 5 ? 
J N N 5 ? 
K N N 6 ? 
L N N 6 ? 
M N N 5 ? 
N N N 4 ? 
O N N 5 ? 
P N N 5 ? 
Q N N 4 ? 
R N N 6 ? 
S N N 7 ? 
T N N 7 ? 
U N N 7 ? 
V N N 7 ? 
W N N 7 ? 
X N N 7 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9R2E        9R2E   ?        1 ? 1   
2 PDB 9R2E        9R2E   ?        2 ? 1   
3 UNP IGHA1_HUMAN P01876 P01876-1 3 
;CHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGVTFTWTPSSGKSAVQGPPERDLCGCYSVSSVLPGCAEPWNHGKTF
TCTAAYPESKTPLTATLSKSGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASR
QEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGK
;
123 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9R2E H 1 ? 244 ? 9R2E   -17 ? 226 ? -17 226 
2 2 9R2E L 1 ? 235 ? 9R2E   -18 ? 216 ? -18 216 
3 3 9R2E P 1 ? 213 ? P01876 123 ? 335 ? 242 454 
4 3 9R2E Q 1 ? 213 ? P01876 123 ? 335 ? 242 454 
5 1 9R2E A 1 ? 244 ? 9R2E   -17 ? 226 ? -17 226 
6 2 9R2E B 1 ? 235 ? 9R2E   -18 ? 216 ? -18 216 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 15390 ? 
1 MORE         -68   ? 
1 'SSA (A^2)'  57620 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 47  ? TYR A 51  ? THR H 29  TYR H 33  5 ? 5 
HELX_P HELX_P2  AA2 ARG A 106 ? THR A 110 ? ARG H 88  THR H 92  5 ? 5 
HELX_P HELX_P3  AA3 SER A 180 ? ALA A 182 ? SER H 162 ALA H 164 5 ? 3 
HELX_P HELX_P4  AA4 SER A 211 ? LEU A 213 ? SER H 193 LEU H 195 5 ? 3 
HELX_P HELX_P5  AA5 LYS A 225 ? ASN A 228 ? LYS H 207 ASN H 210 5 ? 4 
HELX_P HELX_P6  AA6 GLN B 100 ? GLU B 104 ? GLN L 81  GLU L 85  5 ? 5 
HELX_P HELX_P7  AA7 SER B 144 ? ALA B 150 ? SER L 125 ALA L 131 1 ? 7 
HELX_P HELX_P8  AA8 THR B 204 ? SER B 210 ? THR L 185 SER L 191 1 ? 7 
HELX_P HELX_P9  AA9 ALA C 11  ? GLY C 18  ? ALA P 252 GLY P 259 1 ? 8 
HELX_P HELX_P10 AB1 CYS C 70  ? GLY C 77  ? CYS P 311 GLY P 318 1 ? 8 
HELX_P HELX_P11 AB2 PRO C 114 ? ASN C 121 ? PRO P 355 ASN P 362 1 ? 8 
HELX_P HELX_P12 AB3 PRO C 150 ? TYR C 154 ? PRO P 391 TYR P 395 5 ? 5 
HELX_P HELX_P13 AB4 ALA C 180 ? LYS C 185 ? ALA P 421 LYS P 426 1 ? 6 
HELX_P HELX_P14 AB5 ALA D 11  ? GLY D 18  ? ALA Q 252 GLY Q 259 1 ? 8 
HELX_P HELX_P15 AB6 CYS D 70  ? GLY D 77  ? CYS Q 311 GLY Q 318 1 ? 8 
HELX_P HELX_P16 AB7 PRO D 114 ? ASN D 121 ? PRO Q 355 ASN Q 362 1 ? 8 
HELX_P HELX_P17 AB8 PRO D 150 ? GLU D 152 ? PRO Q 391 GLU Q 393 5 ? 3 
HELX_P HELX_P18 AB9 ALA D 180 ? GLY D 186 ? ALA Q 421 GLY Q 427 1 ? 7 
HELX_P HELX_P19 AC1 THR E 47  ? TYR E 51  ? THR A 29  TYR A 33  5 ? 5 
HELX_P HELX_P20 AC2 ARG E 106 ? THR E 110 ? ARG A 88  THR A 92  5 ? 5 
HELX_P HELX_P21 AC3 SER E 180 ? ALA E 182 ? SER A 162 ALA A 164 5 ? 3 
HELX_P HELX_P22 AC4 LYS E 225 ? ASN E 228 ? LYS A 207 ASN A 210 5 ? 4 
HELX_P HELX_P23 AC5 GLN F 100 ? GLU F 104 ? GLN B 81  GLU B 85  5 ? 5 
HELX_P HELX_P24 AC6 SER F 144 ? ALA F 150 ? SER B 125 ALA B 131 1 ? 7 
HELX_P HELX_P25 AC7 THR F 204 ? SER F 210 ? THR B 185 SER B 191 1 ? 7 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ? ? A CYS 41  SG  ? ? ? 1_555 A CYS 115 SG ? ? H CYS 23  H CYS 97  1_555 ? ? ? ? ? ? ? 2.042 ? ? 
disulf2  disulf ? ? A CYS 164 SG  ? ? ? 1_555 A CYS 220 SG ? ? H CYS 146 H CYS 202 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
disulf3  disulf ? ? A CYS 240 SG  ? ? ? 1_555 B CYS 234 SG ? ? H CYS 222 L CYS 215 1_555 ? ? ? ? ? ? ? 2.048 ? ? 
disulf4  disulf ? ? B CYS 41  SG  ? ? ? 1_555 B CYS 109 SG ? ? L CYS 22  L CYS 90  1_555 ? ? ? ? ? ? ? 2.057 ? ? 
disulf5  disulf ? ? B CYS 157 SG  ? ? ? 1_555 B CYS 216 SG ? ? L CYS 138 L CYS 197 1_555 ? ? ? ? ? ? ? 2.052 ? ? 
disulf6  disulf ? ? C CYS 25  SG  ? ? ? 1_555 C CYS 82  SG ? ? P CYS 266 P CYS 323 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf7  disulf ? ? C CYS 58  SG  ? ? ? 1_555 C CYS 60  SG ? ? P CYS 299 P CYS 301 1_555 ? ? ? ? ? ? ? 2.040 ? ? 
disulf8  disulf ? ? C CYS 128 SG  ? ? ? 1_555 C CYS 191 SG ? ? P CYS 369 P CYS 432 1_555 ? ? ? ? ? ? ? 2.046 ? ? 
disulf9  disulf ? ? D CYS 128 SG  ? ? ? 1_555 D CYS 191 SG ? ? Q CYS 369 Q CYS 432 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
disulf10 disulf ? ? E CYS 41  SG  ? ? ? 1_555 E CYS 115 SG ? ? A CYS 23  A CYS 97  1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf11 disulf ? ? E CYS 164 SG  ? ? ? 1_555 E CYS 220 SG ? ? A CYS 146 A CYS 202 1_555 ? ? ? ? ? ? ? 2.043 ? ? 
disulf12 disulf ? ? E CYS 240 SG  ? ? ? 1_555 F CYS 234 SG ? ? A CYS 222 B CYS 215 1_555 ? ? ? ? ? ? ? 2.035 ? ? 
disulf13 disulf ? ? F CYS 41  SG  ? ? ? 1_555 F CYS 109 SG ? ? B CYS 22  B CYS 90  1_555 ? ? ? ? ? ? ? 2.047 ? ? 
disulf14 disulf ? ? F CYS 157 SG  ? ? ? 1_555 F CYS 216 SG ? ? B CYS 138 B CYS 197 1_555 ? ? ? ? ? ? ? 2.042 ? ? 
metalc1  metalc ? ? B HIS 211 NE2 ? ? ? 1_555 K MG  .   MG ? ? L HIS 192 L MG  302 1_555 ? ? ? ? ? ? ? 2.216 ? ? 
metalc2  metalc ? ? B HIS 211 NE2 ? ? ? 1_555 K MG  .   MG ? ? L HIS 192 L MG  302 2_656 ? ? ? ? ? ? ? 2.382 ? ? 
metalc3  metalc ? ? K MG  .   MG  ? ? ? 1_555 T HOH .   O  ? ? L MG  302 L HOH 463 2_656 ? ? ? ? ? ? ? 2.379 ? ? 
metalc4  metalc ? ? K MG  .   MG  ? ? ? 1_555 T HOH .   O  ? ? L MG  302 L HOH 470 1_555 ? ? ? ? ? ? ? 2.798 ? ? 
metalc5  metalc ? ? K MG  .   MG  ? ? ? 1_555 T HOH .   O  ? ? L MG  302 L HOH 470 2_656 ? ? ? ? ? ? ? 2.555 ? ? 
metalc6  metalc ? ? C GLU 72  OE2 ? ? ? 1_555 L MG  .   MG ? ? P GLU 313 P MG  501 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
metalc7  metalc ? ? C GLU 72  OE2 ? ? ? 1_555 L MG  .   MG ? ? P GLU 313 P MG  501 2_556 ? ? ? ? ? ? ? 2.032 ? ? 
metalc8  metalc ? ? C HIS 76  NE2 ? ? ? 1_555 L MG  .   MG ? ? P HIS 317 P MG  501 1_555 ? ? ? ? ? ? ? 2.473 ? ? 
metalc9  metalc ? ? C HIS 76  NE2 ? ? ? 1_555 L MG  .   MG ? ? P HIS 317 P MG  501 2_556 ? ? ? ? ? ? ? 2.474 ? ? 
metalc10 metalc ? ? F HIS 211 NE2 ? ? ? 1_555 R MG  .   MG ? ? B HIS 192 B MG  301 1_555 ? ? ? ? ? ? ? 2.184 ? ? 
metalc11 metalc ? ? F HIS 211 NE2 ? ? ? 1_555 R MG  .   MG ? ? B HIS 192 B MG  301 2_655 ? ? ? ? ? ? ? 2.183 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? B HIS 211 ? L HIS 192 ? 1_555 MG ? K MG . ? L MG 302 ? 1_555 NE2 ? B HIS 211 ? L HIS 192 ? 1_555 0.0   ? 
2  NE2 ? B HIS 211 ? L HIS 192 ? 1_555 MG ? K MG . ? L MG 302 ? 1_555 O   ? T HOH .   ? L HOH 463 ? 2_656 116.1 ? 
3  NE2 ? B HIS 211 ? L HIS 192 ? 1_555 MG ? K MG . ? L MG 302 ? 1_555 O   ? T HOH .   ? L HOH 463 ? 2_656 116.1 ? 
4  NE2 ? B HIS 211 ? L HIS 192 ? 1_555 MG ? K MG . ? L MG 302 ? 1_555 O   ? T HOH .   ? L HOH 470 ? 1_555 98.7  ? 
5  NE2 ? B HIS 211 ? L HIS 192 ? 1_555 MG ? K MG . ? L MG 302 ? 1_555 O   ? T HOH .   ? L HOH 470 ? 1_555 98.7  ? 
6  O   ? T HOH .   ? L HOH 463 ? 2_656 MG ? K MG . ? L MG 302 ? 1_555 O   ? T HOH .   ? L HOH 470 ? 1_555 134.2 ? 
7  NE2 ? B HIS 211 ? L HIS 192 ? 1_555 MG ? K MG . ? L MG 302 ? 1_555 O   ? T HOH .   ? L HOH 470 ? 2_656 96.8  ? 
8  NE2 ? B HIS 211 ? L HIS 192 ? 1_555 MG ? K MG . ? L MG 302 ? 1_555 O   ? T HOH .   ? L HOH 470 ? 2_656 96.8  ? 
9  O   ? T HOH .   ? L HOH 463 ? 2_656 MG ? K MG . ? L MG 302 ? 1_555 O   ? T HOH .   ? L HOH 470 ? 2_656 125.2 ? 
10 O   ? T HOH .   ? L HOH 470 ? 1_555 MG ? K MG . ? L MG 302 ? 1_555 O   ? T HOH .   ? L HOH 470 ? 2_656 14.5  ? 
11 OE2 ? C GLU 72  ? P GLU 313 ? 1_555 MG ? L MG . ? P MG 501 ? 1_555 OE2 ? C GLU 72  ? P GLU 313 ? 1_555 0.0   ? 
12 OE2 ? C GLU 72  ? P GLU 313 ? 1_555 MG ? L MG . ? P MG 501 ? 1_555 NE2 ? C HIS 76  ? P HIS 317 ? 1_555 78.6  ? 
13 OE2 ? C GLU 72  ? P GLU 313 ? 1_555 MG ? L MG . ? P MG 501 ? 1_555 NE2 ? C HIS 76  ? P HIS 317 ? 1_555 78.6  ? 
14 OE2 ? C GLU 72  ? P GLU 313 ? 1_555 MG ? L MG . ? P MG 501 ? 1_555 NE2 ? C HIS 76  ? P HIS 317 ? 1_555 78.6  ? 
15 OE2 ? C GLU 72  ? P GLU 313 ? 1_555 MG ? L MG . ? P MG 501 ? 1_555 NE2 ? C HIS 76  ? P HIS 317 ? 1_555 78.6  ? 
16 NE2 ? C HIS 76  ? P HIS 317 ? 1_555 MG ? L MG . ? P MG 501 ? 1_555 NE2 ? C HIS 76  ? P HIS 317 ? 1_555 0.0   ? 
17 NE2 ? F HIS 211 ? B HIS 192 ? 1_555 MG ? R MG . ? B MG 301 ? 1_555 NE2 ? F HIS 211 ? B HIS 192 ? 1_555 0.0   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  CYS A 41  ? CYS A 115 ? CYS H 23  ? 1_555 CYS H 97  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2  CYS A 164 ? CYS A 220 ? CYS H 146 ? 1_555 CYS H 202 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3  CYS A 240 ? CYS B 234 ? CYS H 222 ? 1_555 CYS L 215 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4  CYS B 41  ? CYS B 109 ? CYS L 22  ? 1_555 CYS L 90  ? 1_555 SG SG . . . None 'Disulfide bridge' 
5  CYS B 157 ? CYS B 216 ? CYS L 138 ? 1_555 CYS L 197 ? 1_555 SG SG . . . None 'Disulfide bridge' 
6  CYS C 25  ? CYS C 82  ? CYS P 266 ? 1_555 CYS P 323 ? 1_555 SG SG . . . None 'Disulfide bridge' 
7  CYS C 58  ? CYS C 60  ? CYS P 299 ? 1_555 CYS P 301 ? 1_555 SG SG . . . None 'Disulfide bridge' 
8  CYS C 128 ? CYS C 191 ? CYS P 369 ? 1_555 CYS P 432 ? 1_555 SG SG . . . None 'Disulfide bridge' 
9  CYS D 128 ? CYS D 191 ? CYS Q 369 ? 1_555 CYS Q 432 ? 1_555 SG SG . . . None 'Disulfide bridge' 
10 CYS E 41  ? CYS E 115 ? CYS A 23  ? 1_555 CYS A 97  ? 1_555 SG SG . . . None 'Disulfide bridge' 
11 CYS E 164 ? CYS E 220 ? CYS A 146 ? 1_555 CYS A 202 ? 1_555 SG SG . . . None 'Disulfide bridge' 
12 CYS E 240 ? CYS F 234 ? CYS A 222 ? 1_555 CYS B 215 ? 1_555 SG SG . . . None 'Disulfide bridge' 
13 CYS F 41  ? CYS F 109 ? CYS B 22  ? 1_555 CYS B 90  ? 1_555 SG SG . . . None 'Disulfide bridge' 
14 CYS F 157 ? CYS F 216 ? CYS B 138 ? 1_555 CYS B 197 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 170 A . ? PHE 152 H PRO 171 A ? PRO 153 H 1 -5.00 
2 GLU 172 A . ? GLU 154 H PRO 173 A ? PRO 155 H 1 -3.99 
3 TYR 163 B . ? TYR 144 L PRO 164 B ? PRO 145 L 1 -8.20 
4 PHE 170 E . ? PHE 152 A PRO 171 E ? PRO 153 A 1 -7.02 
5 GLU 172 E . ? GLU 154 A PRO 173 E ? PRO 155 A 1 -5.26 
6 TYR 163 F . ? TYR 144 B PRO 164 F ? PRO 145 B 1 -6.56 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 6 ? 
AA8 ? 4 ? 
AA9 ? 3 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 4 ? 
AB5 ? 3 ? 
AB6 ? 4 ? 
AB7 ? 4 ? 
AB8 ? 4 ? 
AB9 ? 4 ? 
AC1 ? 3 ? 
AC2 ? 4 ? 
AC3 ? 4 ? 
AC4 ? 4 ? 
AC5 ? 4 ? 
AC6 ? 6 ? 
AC7 ? 4 ? 
AC8 ? 4 ? 
AC9 ? 4 ? 
AD1 ? 3 ? 
AD2 ? 6 ? 
AD3 ? 4 ? 
AD4 ? 3 ? 
AD5 ? 4 ? 
AD6 ? 4 ? 
AD7 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA7 5 6 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC6 1 2 ? parallel      
AC6 2 3 ? anti-parallel 
AC6 3 4 ? anti-parallel 
AC6 4 5 ? anti-parallel 
AC6 5 6 ? anti-parallel 
AC7 1 2 ? parallel      
AC7 2 3 ? anti-parallel 
AC7 3 4 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC8 2 3 ? anti-parallel 
AC8 3 4 ? anti-parallel 
AC9 1 2 ? anti-parallel 
AC9 2 3 ? anti-parallel 
AC9 3 4 ? anti-parallel 
AD1 1 2 ? anti-parallel 
AD1 2 3 ? anti-parallel 
AD2 1 2 ? parallel      
AD2 2 3 ? anti-parallel 
AD2 3 4 ? anti-parallel 
AD2 4 5 ? anti-parallel 
AD2 5 6 ? anti-parallel 
AD3 1 2 ? parallel      
AD3 2 3 ? anti-parallel 
AD3 3 4 ? anti-parallel 
AD4 1 2 ? anti-parallel 
AD4 2 3 ? anti-parallel 
AD5 1 2 ? anti-parallel 
AD5 2 3 ? anti-parallel 
AD5 3 4 ? anti-parallel 
AD6 1 2 ? anti-parallel 
AD6 2 3 ? anti-parallel 
AD6 3 4 ? anti-parallel 
AD7 1 2 ? anti-parallel 
AD7 2 3 ? anti-parallel 
AD7 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 22  ? SER A 26  ? GLN H 4   SER H 8   
AA1 2 LEU A 37  ? SER A 44  ? LEU H 19  SER H 26  
AA1 3 THR A 97  ? MET A 102 ? THR H 79  MET H 84  
AA1 4 PHE A 87  ? ASP A 92  ? PHE H 69  ASP H 74  
AA2 1 LEU A 30  ? VAL A 31  ? LEU H 12  VAL H 13  
AA2 2 THR A 131 ? VAL A 135 ? THR H 113 VAL H 117 
AA2 3 ALA A 111 ? VAL A 118 ? ALA H 93  VAL H 100 
AA2 4 MET A 53  ? GLN A 58  ? MET H 35  GLN H 40  
AA2 5 LEU A 64  ? ILE A 70  ? LEU H 46  ILE H 52  
AA2 6 ALA A 77  ? TYR A 79  ? ALA H 59  TYR H 61  
AA3 1 LEU A 30  ? VAL A 31  ? LEU H 12  VAL H 13  
AA3 2 THR A 131 ? VAL A 135 ? THR H 113 VAL H 117 
AA3 3 ALA A 111 ? VAL A 118 ? ALA H 93  VAL H 100 
AA3 4 PHE A 124 ? TRP A 127 ? PHE H 106 TRP H 109 
AA4 1 SER A 144 ? LEU A 148 ? SER H 126 LEU H 130 
AA4 2 THR A 159 ? TYR A 169 ? THR H 141 TYR H 151 
AA4 3 TYR A 200 ? PRO A 209 ? TYR H 182 PRO H 191 
AA4 4 VAL A 187 ? THR A 189 ? VAL H 169 THR H 171 
AA5 1 SER A 144 ? LEU A 148 ? SER H 126 LEU H 130 
AA5 2 THR A 159 ? TYR A 169 ? THR H 141 TYR H 151 
AA5 3 TYR A 200 ? PRO A 209 ? TYR H 182 PRO H 191 
AA5 4 VAL A 193 ? LEU A 194 ? VAL H 175 LEU H 176 
AA6 1 THR A 175 ? TRP A 178 ? THR H 157 TRP H 160 
AA6 2 ILE A 219 ? HIS A 224 ? ILE H 201 HIS H 206 
AA6 3 THR A 229 ? LYS A 234 ? THR H 211 LYS H 216 
AA7 1 SER B 28  ? GLY B 31  ? SER L 9   GLY L 12  
AA7 2 THR B 124 ? VAL B 128 ? THR L 105 VAL L 109 
AA7 3 ALA B 105 ? HIS B 112 ? ALA L 86  HIS L 93  
AA7 4 VAL B 54  ? GLN B 59  ? VAL L 35  GLN L 40  
AA7 5 LYS B 66  ? TYR B 70  ? LYS L 47  TYR L 51  
AA7 6 ILE B 74  ? ARG B 75  ? ILE L 55  ARG L 56  
AA8 1 SER B 28  ? GLY B 31  ? SER L 9   GLY L 12  
AA8 2 THR B 124 ? VAL B 128 ? THR L 105 VAL L 109 
AA8 3 ALA B 105 ? HIS B 112 ? ALA L 86  HIS L 93  
AA8 4 ILE B 118 ? PHE B 120 ? ILE L 99  PHE L 101 
AA9 1 VAL B 37  ? ALA B 42  ? VAL L 18  ALA L 23  
AA9 2 SER B 91  ? ILE B 96  ? SER L 72  ILE L 77  
AA9 3 PHE B 83  ? SER B 88  ? PHE L 64  SER L 69  
AB1 1 SER B 137 ? PHE B 141 ? SER L 118 PHE L 122 
AB1 2 ALA B 153 ? PHE B 162 ? ALA L 134 PHE L 143 
AB1 3 TYR B 195 ? LEU B 203 ? TYR L 176 LEU L 184 
AB1 4 VAL B 182 ? THR B 184 ? VAL L 163 THR L 165 
AB2 1 SER B 137 ? PHE B 141 ? SER L 118 PHE L 122 
AB2 2 ALA B 153 ? PHE B 162 ? ALA L 134 PHE L 143 
AB2 3 TYR B 195 ? LEU B 203 ? TYR L 176 LEU L 184 
AB2 4 SER B 188 ? LYS B 189 ? SER L 169 LYS L 170 
AB3 1 SER B 176 ? VAL B 178 ? SER L 157 VAL L 159 
AB3 2 THR B 168 ? ALA B 173 ? THR L 149 ALA L 154 
AB3 3 TYR B 214 ? HIS B 220 ? TYR L 195 HIS L 201 
AB3 4 SER B 223 ? VAL B 229 ? SER L 204 VAL L 210 
AB4 1 LEU C 5   ? HIS C 8   ? LEU P 246 HIS P 249 
AB4 2 LEU C 23  ? LEU C 27  ? LEU P 264 LEU P 268 
AB4 3 VAL C 63  ? LEU C 67  ? VAL P 304 LEU P 308 
AB4 4 VAL C 49  ? GLN C 50  ? VAL P 290 GLN P 291 
AB5 1 THR C 37  ? TRP C 40  ? THR P 278 TRP P 281 
AB5 2 PHE C 80  ? ALA C 85  ? PHE P 321 ALA P 326 
AB5 3 THR C 96  ? LEU C 97  ? THR P 337 LEU P 338 
AB6 1 GLU C 107 ? LEU C 111 ? GLU P 348 LEU P 352 
AB6 2 LEU C 123 ? PHE C 133 ? LEU P 364 PHE P 374 
AB6 3 PHE C 170 ? ALA C 179 ? PHE P 411 ALA P 420 
AB6 4 LEU C 155 ? THR C 156 ? LEU P 396 THR P 397 
AB7 1 GLU C 107 ? LEU C 111 ? GLU P 348 LEU P 352 
AB7 2 LEU C 123 ? PHE C 133 ? LEU P 364 PHE P 374 
AB7 3 PHE C 170 ? ALA C 179 ? PHE P 411 ALA P 420 
AB7 4 ARG C 160 ? GLN C 161 ? ARG P 401 GLN P 402 
AB8 1 GLN C 147 ? GLU C 148 ? GLN P 388 GLU P 389 
AB8 2 LEU C 139 ? GLN C 144 ? LEU P 380 GLN P 385 
AB8 3 PHE C 189 ? GLY C 194 ? PHE P 430 GLY P 435 
AB8 4 PHE C 202 ? ILE C 207 ? PHE P 443 ILE P 448 
AB9 1 ARG D 4   ? HIS D 8   ? ARG Q 245 HIS Q 249 
AB9 2 LEU D 23  ? THR D 28  ? LEU Q 264 THR Q 269 
AB9 3 SER D 62  ? LEU D 67  ? SER Q 303 LEU Q 308 
AB9 4 VAL D 49  ? GLU D 54  ? VAL Q 290 GLU Q 295 
AC1 1 THR D 37  ? TRP D 40  ? THR Q 278 TRP Q 281 
AC1 2 PHE D 80  ? ALA D 85  ? PHE Q 321 ALA Q 326 
AC1 3 THR D 96  ? LEU D 97  ? THR Q 337 LEU Q 338 
AC2 1 GLU D 107 ? LEU D 111 ? GLU Q 348 LEU Q 352 
AC2 2 LEU D 123 ? PHE D 133 ? LEU Q 364 PHE Q 374 
AC2 3 PHE D 170 ? ALA D 179 ? PHE Q 411 ALA Q 420 
AC2 4 TYR D 154 ? THR D 156 ? TYR Q 395 THR Q 397 
AC3 1 GLU D 107 ? LEU D 111 ? GLU Q 348 LEU Q 352 
AC3 2 LEU D 123 ? PHE D 133 ? LEU Q 364 PHE Q 374 
AC3 3 PHE D 170 ? ALA D 179 ? PHE Q 411 ALA Q 420 
AC3 4 ARG D 160 ? GLN D 161 ? ARG Q 401 GLN Q 402 
AC4 1 GLN D 147 ? GLU D 148 ? GLN Q 388 GLU Q 389 
AC4 2 LEU D 139 ? GLN D 144 ? LEU Q 380 GLN Q 385 
AC4 3 PHE D 189 ? GLY D 194 ? PHE Q 430 GLY Q 435 
AC4 4 PHE D 202 ? ILE D 207 ? PHE Q 443 ILE Q 448 
AC5 1 GLN E 22  ? SER E 26  ? GLN A 4   SER A 8   
AC5 2 LEU E 37  ? SER E 44  ? LEU A 19  SER A 26  
AC5 3 THR E 97  ? MET E 102 ? THR A 79  MET A 84  
AC5 4 THR E 88  ? ASP E 92  ? THR A 70  ASP A 74  
AC6 1 LEU E 30  ? VAL E 31  ? LEU A 12  VAL A 13  
AC6 2 THR E 131 ? VAL E 135 ? THR A 113 VAL A 117 
AC6 3 ALA E 111 ? VAL E 118 ? ALA A 93  VAL A 100 
AC6 4 MET E 53  ? GLN E 58  ? MET A 35  GLN A 40  
AC6 5 LEU E 64  ? ILE E 70  ? LEU A 46  ILE A 52  
AC6 6 ALA E 77  ? TYR E 79  ? ALA A 59  TYR A 61  
AC7 1 LEU E 30  ? VAL E 31  ? LEU A 12  VAL A 13  
AC7 2 THR E 131 ? VAL E 135 ? THR A 113 VAL A 117 
AC7 3 ALA E 111 ? VAL E 118 ? ALA A 93  VAL A 100 
AC7 4 PHE E 124 ? TRP E 127 ? PHE A 106 TRP A 109 
AC8 1 SER E 144 ? LEU E 148 ? SER A 126 LEU A 130 
AC8 2 THR E 159 ? TYR E 169 ? THR A 141 TYR A 151 
AC8 3 TYR E 200 ? PRO E 209 ? TYR A 182 PRO A 191 
AC8 4 VAL E 187 ? THR E 189 ? VAL A 169 THR A 171 
AC9 1 SER E 144 ? LEU E 148 ? SER A 126 LEU A 130 
AC9 2 THR E 159 ? TYR E 169 ? THR A 141 TYR A 151 
AC9 3 TYR E 200 ? PRO E 209 ? TYR A 182 PRO A 191 
AC9 4 VAL E 193 ? LEU E 194 ? VAL A 175 LEU A 176 
AD1 1 THR E 175 ? TRP E 178 ? THR A 157 TRP A 160 
AD1 2 ILE E 219 ? HIS E 224 ? ILE A 201 HIS A 206 
AD1 3 THR E 229 ? LYS E 234 ? THR A 211 LYS A 216 
AD2 1 SER F 28  ? GLY F 31  ? SER B 9   GLY B 12  
AD2 2 THR F 124 ? VAL F 128 ? THR B 105 VAL B 109 
AD2 3 ASP F 106 ? HIS F 112 ? ASP B 87  HIS B 93  
AD2 4 VAL F 54  ? GLN F 59  ? VAL B 35  GLN B 40  
AD2 5 LYS F 66  ? TYR F 70  ? LYS B 47  TYR B 51  
AD2 6 ILE F 74  ? ARG F 75  ? ILE B 55  ARG B 56  
AD3 1 SER F 28  ? GLY F 31  ? SER B 9   GLY B 12  
AD3 2 THR F 124 ? VAL F 128 ? THR B 105 VAL B 109 
AD3 3 ASP F 106 ? HIS F 112 ? ASP B 87  HIS B 93  
AD3 4 ILE F 118 ? PHE F 120 ? ILE B 99  PHE B 101 
AD4 1 VAL F 37  ? ALA F 42  ? VAL B 18  ALA B 23  
AD4 2 SER F 91  ? ILE F 96  ? SER B 72  ILE B 77  
AD4 3 PHE F 83  ? SER F 88  ? PHE B 64  SER B 69  
AD5 1 SER F 137 ? PHE F 141 ? SER B 118 PHE B 122 
AD5 2 ALA F 153 ? PHE F 162 ? ALA B 134 PHE B 143 
AD5 3 TYR F 195 ? LEU F 203 ? TYR B 176 LEU B 184 
AD5 4 VAL F 182 ? THR F 184 ? VAL B 163 THR B 165 
AD6 1 SER F 137 ? PHE F 141 ? SER B 118 PHE B 122 
AD6 2 ALA F 153 ? PHE F 162 ? ALA B 134 PHE B 143 
AD6 3 TYR F 195 ? LEU F 203 ? TYR B 176 LEU B 184 
AD6 4 SER F 188 ? LYS F 189 ? SER B 169 LYS B 170 
AD7 1 SER F 176 ? VAL F 178 ? SER B 157 VAL B 159 
AD7 2 THR F 168 ? ALA F 173 ? THR B 149 ALA B 154 
AD7 3 TYR F 214 ? HIS F 220 ? TYR B 195 HIS B 201 
AD7 4 SER F 223 ? VAL F 229 ? SER B 204 VAL B 210 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 26  ? N SER H 8   O SER A 40  ? O SER H 22  
AA1 2 3 N LEU A 39  ? N LEU H 21  O LEU A 100 ? O LEU H 82  
AA1 3 4 O GLN A 101 ? O GLN H 83  N THR A 88  ? N THR H 70  
AA2 1 2 N VAL A 31  ? N VAL H 13  O THR A 134 ? O THR H 116 
AA2 2 3 O VAL A 133 ? O VAL H 115 N ALA A 111 ? N ALA H 93  
AA2 3 4 O TYR A 114 ? O TYR H 96  N VAL A 56  ? N VAL H 38  
AA2 4 5 N ARG A 57  ? N ARG H 39  O GLU A 65  ? O GLU H 47  
AA2 5 6 N SER A 69  ? N SER H 51  O TYR A 78  ? O TYR H 60  
AA3 1 2 N VAL A 31  ? N VAL H 13  O THR A 134 ? O THR H 116 
AA3 2 3 O VAL A 133 ? O VAL H 115 N ALA A 111 ? N ALA H 93  
AA3 3 4 N LYS A 117 ? N LYS H 99  O SER A 126 ? O SER H 108 
AA4 1 2 N SER A 144 ? N SER H 126 O LYS A 167 ? O LYS H 149 
AA4 2 3 N TYR A 169 ? N TYR H 151 O TYR A 200 ? O TYR H 182 
AA4 3 4 O VAL A 205 ? O VAL H 187 N HIS A 188 ? N HIS H 170 
AA5 1 2 N SER A 144 ? N SER H 126 O LYS A 167 ? O LYS H 149 
AA5 2 3 N TYR A 169 ? N TYR H 151 O TYR A 200 ? O TYR H 182 
AA5 3 4 O SER A 201 ? O SER H 183 N VAL A 193 ? N VAL H 175 
AA6 1 2 N SER A 177 ? N SER H 159 O ASN A 221 ? O ASN H 203 
AA6 2 3 N VAL A 222 ? N VAL H 204 O VAL A 231 ? O VAL H 213 
AA7 1 2 N VAL B 29  ? N VAL L 10  O LYS B 125 ? O LYS L 106 
AA7 2 3 O THR B 124 ? O THR L 105 N TYR B 107 ? N TYR L 88  
AA7 3 4 O TYR B 108 ? O TYR L 89  N TYR B 57  ? N TYR L 38  
AA7 4 5 N TRP B 56  ? N TRP L 37  O LEU B 68  ? O LEU L 49  
AA7 5 6 N TYR B 70  ? N TYR L 51  O ILE B 74  ? O ILE L 55  
AA8 1 2 N VAL B 29  ? N VAL L 10  O LYS B 125 ? O LYS L 106 
AA8 2 3 O THR B 124 ? O THR L 105 N TYR B 107 ? N TYR L 88  
AA8 3 4 N SER B 111 ? N SER L 92  O VAL B 119 ? O VAL L 100 
AA9 1 2 N VAL B 37  ? N VAL L 18  O ILE B 96  ? O ILE L 77  
AA9 2 3 O ALA B 95  ? O ALA L 76  N SER B 84  ? N SER L 65  
AB1 1 2 N SER B 137 ? N SER L 118 O SER B 160 ? O SER L 141 
AB1 2 3 N CYS B 157 ? N CYS L 138 O SER B 199 ? O SER L 180 
AB1 3 4 O TYR B 200 ? O TYR L 181 N GLU B 183 ? N GLU L 164 
AB2 1 2 N SER B 137 ? N SER L 118 O SER B 160 ? O SER L 141 
AB2 2 3 N CYS B 157 ? N CYS L 138 O SER B 199 ? O SER L 180 
AB2 3 4 O ALA B 196 ? O ALA L 177 N SER B 188 ? N SER L 169 
AB3 1 2 O SER B 176 ? O SER L 157 N ALA B 173 ? N ALA L 154 
AB3 2 3 N ALA B 170 ? N ALA L 151 O GLN B 217 ? O GLN L 198 
AB3 3 4 N TYR B 214 ? N TYR L 195 O VAL B 229 ? O VAL L 210 
AB4 1 2 N HIS C 8   ? N HIS P 249 O THR C 24  ? O THR P 265 
AB4 2 3 N LEU C 27  ? N LEU P 268 O VAL C 63  ? O VAL P 304 
AB4 3 4 O VAL C 66  ? O VAL P 307 N VAL C 49  ? N VAL P 290 
AB5 1 2 N THR C 39  ? N THR P 280 O THR C 83  ? O THR P 324 
AB5 2 3 N PHE C 80  ? N PHE P 321 O LEU C 97  ? O LEU P 338 
AB6 1 2 N GLU C 107 ? N GLU P 348 O ARG C 131 ? O ARG P 372 
AB6 2 3 N CYS C 128 ? N CYS P 369 O SER C 174 ? O SER P 415 
AB6 3 4 O ILE C 175 ? O ILE P 416 N LEU C 155 ? N LEU P 396 
AB7 1 2 N GLU C 107 ? N GLU P 348 O ARG C 131 ? O ARG P 372 
AB7 2 3 N CYS C 128 ? N CYS P 369 O SER C 174 ? O SER P 415 
AB7 3 4 O ALA C 171 ? O ALA P 412 N ARG C 160 ? N ARG P 401 
AB8 1 2 O GLN C 147 ? O GLN P 388 N GLN C 144 ? N GLN P 385 
AB8 2 3 N ARG C 141 ? N ARG P 382 O MET C 192 ? O MET P 433 
AB8 3 4 N PHE C 189 ? N PHE P 430 O ILE C 207 ? O ILE P 448 
AB9 1 2 N HIS D 8   ? N HIS Q 249 O THR D 24  ? O THR Q 265 
AB9 2 3 N CYS D 25  ? N CYS Q 266 O SER D 65  ? O SER Q 306 
AB9 3 4 O VAL D 66  ? O VAL Q 307 N VAL D 49  ? N VAL Q 290 
AC1 1 2 N THR D 37  ? N THR Q 278 O ALA D 85  ? O ALA Q 326 
AC1 2 3 N PHE D 80  ? N PHE Q 321 O LEU D 97  ? O LEU Q 338 
AC2 1 2 N GLU D 107 ? N GLU Q 348 O ARG D 131 ? O ARG Q 372 
AC2 2 3 N CYS D 128 ? N CYS Q 369 O SER D 174 ? O SER Q 415 
AC2 3 4 O ILE D 175 ? O ILE Q 416 N LEU D 155 ? N LEU Q 396 
AC3 1 2 N GLU D 107 ? N GLU Q 348 O ARG D 131 ? O ARG Q 372 
AC3 2 3 N CYS D 128 ? N CYS Q 369 O SER D 174 ? O SER Q 415 
AC3 3 4 O ALA D 171 ? O ALA Q 412 N ARG D 160 ? N ARG Q 401 
AC4 1 2 O GLN D 147 ? O GLN Q 388 N GLN D 144 ? N GLN Q 385 
AC4 2 3 N ARG D 141 ? N ARG Q 382 O MET D 192 ? O MET Q 433 
AC4 3 4 N VAL D 193 ? N VAL Q 434 O THR D 203 ? O THR Q 444 
AC5 1 2 N SER E 26  ? N SER A 8   O SER E 40  ? O SER A 22  
AC5 2 3 N LEU E 37  ? N LEU A 19  O MET E 102 ? O MET A 84  
AC5 3 4 O GLN E 101 ? O GLN A 83  N THR E 88  ? N THR A 70  
AC6 1 2 N VAL E 31  ? N VAL A 13  O THR E 134 ? O THR A 116 
AC6 2 3 O THR E 131 ? O THR A 113 N TYR E 113 ? N TYR A 95  
AC6 3 4 O TYR E 114 ? O TYR A 96  N VAL E 56  ? N VAL A 38  
AC6 4 5 N ARG E 57  ? N ARG A 39  O GLU E 65  ? O GLU A 47  
AC6 5 6 N SER E 69  ? N SER A 51  O TYR E 78  ? O TYR A 60  
AC7 1 2 N VAL E 31  ? N VAL A 13  O THR E 134 ? O THR A 116 
AC7 2 3 O THR E 131 ? O THR A 113 N TYR E 113 ? N TYR A 95  
AC7 3 4 N LYS E 117 ? N LYS A 99  O SER E 126 ? O SER A 108 
AC8 1 2 N SER E 144 ? N SER A 126 O LYS E 167 ? O LYS A 149 
AC8 2 3 N LEU E 162 ? N LEU A 144 O VAL E 206 ? O VAL A 188 
AC8 3 4 O VAL E 205 ? O VAL A 187 N HIS E 188 ? N HIS A 170 
AC9 1 2 N SER E 144 ? N SER A 126 O LYS E 167 ? O LYS A 149 
AC9 2 3 N LEU E 162 ? N LEU A 144 O VAL E 206 ? O VAL A 188 
AC9 3 4 O SER E 201 ? O SER A 183 N VAL E 193 ? N VAL A 175 
AD1 1 2 N SER E 177 ? N SER A 159 O ASN E 221 ? O ASN A 203 
AD1 2 3 N VAL E 222 ? N VAL A 204 O VAL E 231 ? O VAL A 213 
AD2 1 2 N VAL F 29  ? N VAL B 10  O THR F 127 ? O THR B 108 
AD2 2 3 O THR F 124 ? O THR B 105 N TYR F 107 ? N TYR B 88  
AD2 3 4 O TYR F 108 ? O TYR B 89  N TYR F 57  ? N TYR B 38  
AD2 4 5 N TRP F 56  ? N TRP B 37  O LEU F 68  ? O LEU B 49  
AD2 5 6 N TYR F 70  ? N TYR B 51  O ILE F 74  ? O ILE B 55  
AD3 1 2 N VAL F 29  ? N VAL B 10  O THR F 127 ? O THR B 108 
AD3 2 3 O THR F 124 ? O THR B 105 N TYR F 107 ? N TYR B 88  
AD3 3 4 N SER F 111 ? N SER B 92  O VAL F 119 ? O VAL B 100 
AD4 1 2 N VAL F 37  ? N VAL B 18  O ILE F 96  ? O ILE B 77  
AD4 2 3 O ALA F 95  ? O ALA B 76  N SER F 84  ? N SER B 65  
AD5 1 2 N PHE F 141 ? N PHE B 122 O VAL F 156 ? O VAL B 137 
AD5 2 3 N PHE F 162 ? N PHE B 143 O TYR F 195 ? O TYR B 176 
AD5 3 4 O TYR F 200 ? O TYR B 181 N GLU F 183 ? N GLU B 164 
AD6 1 2 N PHE F 141 ? N PHE B 122 O VAL F 156 ? O VAL B 137 
AD6 2 3 N PHE F 162 ? N PHE B 143 O TYR F 195 ? O TYR B 176 
AD6 3 4 O ALA F 196 ? O ALA B 177 N SER F 188 ? N SER B 169 
AD7 1 2 O SER F 176 ? O SER B 157 N ALA F 173 ? N ALA B 154 
AD7 2 3 N ALA F 170 ? N ALA B 151 O GLN F 217 ? O GLN B 198 
AD7 3 4 N VAL F 218 ? N VAL B 199 O VAL F 225 ? O VAL B 206 
# 
_pdbx_entry_details.entry_id                   9R2E 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    L 
_pdbx_validate_symm_contact.auth_comp_id_1    HOH 
_pdbx_validate_symm_contact.auth_seq_id_1     470 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O 
_pdbx_validate_symm_contact.auth_asym_id_2    L 
_pdbx_validate_symm_contact.auth_comp_id_2    HOH 
_pdbx_validate_symm_contact.auth_seq_id_2     470 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   2_656 
_pdbx_validate_symm_contact.dist              0.72 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TYR H 55  ? ? 72.31   -45.12  
2  1 ASP H 101 ? ? -94.30  -130.91 
3  1 ALA H 103 ? ? -141.72 41.24   
4  1 LYS H 135 ? ? -36.75  123.27  
5  1 THR H 137 ? ? 31.73   74.25   
6  1 ASP H 150 ? ? 61.84   62.96   
7  1 THR H 166 ? ? -134.38 -41.11  
8  1 ASP L 28  ? ? -126.28 -89.69  
9  1 TYR L 34  ? ? -98.83  46.31   
10 1 VAL L 53  ? ? 70.22   -57.46  
11 1 ASP L 155 ? ? 58.26   -123.49 
12 1 ASN L 174 ? ? 77.16   -11.61  
13 1 SER P 285 ? ? -117.73 66.71   
14 1 TYR P 302 ? ? 70.09   85.17   
15 1 GLU P 363 ? ? -116.46 -129.71 
16 1 SER P 405 ? ? -171.34 149.15  
17 1 ALA P 442 ? ? 69.30   -51.70  
18 1 LEU P 451 ? ? -91.06  40.96   
19 1 THR Q 282 ? ? -81.54  -72.52  
20 1 SER Q 288 ? ? 52.05   71.59   
21 1 GLU Q 363 ? ? -106.52 -109.47 
22 1 SER Q 405 ? ? -173.32 133.70  
23 1 ALA Q 442 ? ? 71.16   -53.03  
24 1 VAL A 49  ? ? -108.57 -61.02  
25 1 TYR A 55  ? ? 72.60   -60.03  
26 1 ARG A 68  ? ? -128.66 -57.86  
27 1 ASP A 101 ? ? -89.51  -127.26 
28 1 LYS A 135 ? ? -61.52  99.90   
29 1 ASP A 150 ? ? 63.29   64.90   
30 1 ASP B 28  ? ? -127.90 -94.56  
31 1 TYR B 34  ? ? -101.58 53.79   
32 1 LEU B 49  ? ? -97.42  -61.33  
33 1 VAL B 53  ? ? 74.04   -53.27  
34 1 ASP B 155 ? ? 58.54   -120.58 
35 1 ASN B 174 ? ? 81.66   -18.00  
36 1 SER B 191 ? ? -96.47  35.44   
37 1 THR B 213 ? ? -105.40 47.47   
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 P MG 501 ? L MG . 
2 1 B MG 301 ? R MG . 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      B 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       474 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.63 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 H MET -17 ? A MET 1   
2   1 Y 1 H GLY -16 ? A GLY 2   
3   1 Y 1 H TRP -15 ? A TRP 3   
4   1 Y 1 H SER -14 ? A SER 4   
5   1 Y 1 H CYS -13 ? A CYS 5   
6   1 Y 1 H ILE -12 ? A ILE 6   
7   1 Y 1 H ILE -11 ? A ILE 7   
8   1 Y 1 H LEU -10 ? A LEU 8   
9   1 Y 1 H PHE -9  ? A PHE 9   
10  1 Y 1 H LEU -8  ? A LEU 10  
11  1 Y 1 H VAL -7  ? A VAL 11  
12  1 Y 1 H ALA -6  ? A ALA 12  
13  1 Y 1 H THR -5  ? A THR 13  
14  1 Y 1 H ALA -4  ? A ALA 14  
15  1 Y 1 H THR -3  ? A THR 15  
16  1 Y 1 H GLY -2  ? A GLY 16  
17  1 Y 1 H VAL -1  ? A VAL 17  
18  1 Y 1 H HIS 0   ? A HIS 18  
19  1 Y 1 H SER 1   ? A SER 19  
20  1 Y 1 H HIS 226 ? A HIS 244 
21  1 Y 1 L MET -18 ? B MET 1   
22  1 Y 1 L GLY -17 ? B GLY 2   
23  1 Y 1 L TRP -16 ? B TRP 3   
24  1 Y 1 L SER -15 ? B SER 4   
25  1 Y 1 L CYS -14 ? B CYS 5   
26  1 Y 1 L ILE -13 ? B ILE 6   
27  1 Y 1 L ILE -12 ? B ILE 7   
28  1 Y 1 L LEU -11 ? B LEU 8   
29  1 Y 1 L PHE -10 ? B PHE 9   
30  1 Y 1 L LEU -9  ? B LEU 10  
31  1 Y 1 L VAL -8  ? B VAL 11  
32  1 Y 1 L ALA -7  ? B ALA 12  
33  1 Y 1 L THR -6  ? B THR 13  
34  1 Y 1 L ALA -5  ? B ALA 14  
35  1 Y 1 L THR -4  ? B THR 15  
36  1 Y 1 L GLY -3  ? B GLY 16  
37  1 Y 1 L VAL -2  ? B VAL 17  
38  1 Y 1 L HIS -1  ? B HIS 18  
39  1 Y 1 L SER 0   ? B SER 19  
40  1 Y 1 L GLN 1   ? B GLN 20  
41  1 Y 1 L SER 216 ? B SER 235 
42  1 Y 1 P LEU 271 ? C LEU 30  
43  1 Y 1 P ARG 272 ? C ARG 31  
44  1 Y 1 P ASP 273 ? C ASP 32  
45  1 Y 1 P ALA 274 ? C ALA 33  
46  1 Y 1 P SER 275 ? C SER 34  
47  1 Y 1 P GLY 276 ? C GLY 35  
48  1 Y 1 P ARG 296 ? C ARG 55  
49  1 Y 1 P ASP 297 ? C ASP 56  
50  1 Y 1 P LEU 298 ? C LEU 57  
51  1 Y 1 P GLY 453 ? C GLY 212 
52  1 Y 1 P LYS 454 ? C LYS 213 
53  1 Y 1 Q LEU 271 ? D LEU 30  
54  1 Y 1 Q ARG 272 ? D ARG 31  
55  1 Y 1 Q ASP 297 ? D ASP 56  
56  1 Y 1 Q LEU 298 ? D LEU 57  
57  1 Y 1 Q CYS 299 ? D CYS 58  
58  1 Y 1 Q GLY 453 ? D GLY 212 
59  1 Y 1 Q LYS 454 ? D LYS 213 
60  1 Y 1 A MET -17 ? E MET 1   
61  1 Y 1 A GLY -16 ? E GLY 2   
62  1 Y 1 A TRP -15 ? E TRP 3   
63  1 Y 1 A SER -14 ? E SER 4   
64  1 Y 1 A CYS -13 ? E CYS 5   
65  1 Y 1 A ILE -12 ? E ILE 6   
66  1 Y 1 A ILE -11 ? E ILE 7   
67  1 Y 1 A LEU -10 ? E LEU 8   
68  1 Y 1 A PHE -9  ? E PHE 9   
69  1 Y 1 A LEU -8  ? E LEU 10  
70  1 Y 1 A VAL -7  ? E VAL 11  
71  1 Y 1 A ALA -6  ? E ALA 12  
72  1 Y 1 A THR -5  ? E THR 13  
73  1 Y 1 A ALA -4  ? E ALA 14  
74  1 Y 1 A THR -3  ? E THR 15  
75  1 Y 1 A GLY -2  ? E GLY 16  
76  1 Y 1 A VAL -1  ? E VAL 17  
77  1 Y 1 A HIS 0   ? E HIS 18  
78  1 Y 1 A SER 1   ? E SER 19  
79  1 Y 1 A THR 225 ? E THR 243 
80  1 Y 1 A HIS 226 ? E HIS 244 
81  1 Y 1 B MET -18 ? F MET 1   
82  1 Y 1 B GLY -17 ? F GLY 2   
83  1 Y 1 B TRP -16 ? F TRP 3   
84  1 Y 1 B SER -15 ? F SER 4   
85  1 Y 1 B CYS -14 ? F CYS 5   
86  1 Y 1 B ILE -13 ? F ILE 6   
87  1 Y 1 B ILE -12 ? F ILE 7   
88  1 Y 1 B LEU -11 ? F LEU 8   
89  1 Y 1 B PHE -10 ? F PHE 9   
90  1 Y 1 B LEU -9  ? F LEU 10  
91  1 Y 1 B VAL -8  ? F VAL 11  
92  1 Y 1 B ALA -7  ? F ALA 12  
93  1 Y 1 B THR -6  ? F THR 13  
94  1 Y 1 B ALA -5  ? F ALA 14  
95  1 Y 1 B THR -4  ? F THR 15  
96  1 Y 1 B GLY -3  ? F GLY 16  
97  1 Y 1 B VAL -2  ? F VAL 17  
98  1 Y 1 B HIS -1  ? F HIS 18  
99  1 Y 1 B SER 0   ? F SER 19  
100 1 Y 1 B GLN 1   ? F GLN 20  
101 1 Y 1 B SER 216 ? F SER 235 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
EDO C1   C  N N 88  
EDO O1   O  N N 89  
EDO C2   C  N N 90  
EDO O2   O  N N 91  
EDO H11  H  N N 92  
EDO H12  H  N N 93  
EDO HO1  H  N N 94  
EDO H21  H  N N 95  
EDO H22  H  N N 96  
EDO HO2  H  N N 97  
GLN N    N  N N 98  
GLN CA   C  N S 99  
GLN C    C  N N 100 
GLN O    O  N N 101 
GLN CB   C  N N 102 
GLN CG   C  N N 103 
GLN CD   C  N N 104 
GLN OE1  O  N N 105 
GLN NE2  N  N N 106 
GLN OXT  O  N N 107 
GLN H    H  N N 108 
GLN H2   H  N N 109 
GLN HA   H  N N 110 
GLN HB2  H  N N 111 
GLN HB3  H  N N 112 
GLN HG2  H  N N 113 
GLN HG3  H  N N 114 
GLN HE21 H  N N 115 
GLN HE22 H  N N 116 
GLN HXT  H  N N 117 
GLU N    N  N N 118 
GLU CA   C  N S 119 
GLU C    C  N N 120 
GLU O    O  N N 121 
GLU CB   C  N N 122 
GLU CG   C  N N 123 
GLU CD   C  N N 124 
GLU OE1  O  N N 125 
GLU OE2  O  N N 126 
GLU OXT  O  N N 127 
GLU H    H  N N 128 
GLU H2   H  N N 129 
GLU HA   H  N N 130 
GLU HB2  H  N N 131 
GLU HB3  H  N N 132 
GLU HG2  H  N N 133 
GLU HG3  H  N N 134 
GLU HE2  H  N N 135 
GLU HXT  H  N N 136 
GLY N    N  N N 137 
GLY CA   C  N N 138 
GLY C    C  N N 139 
GLY O    O  N N 140 
GLY OXT  O  N N 141 
GLY H    H  N N 142 
GLY H2   H  N N 143 
GLY HA2  H  N N 144 
GLY HA3  H  N N 145 
GLY HXT  H  N N 146 
HIS N    N  N N 147 
HIS CA   C  N S 148 
HIS C    C  N N 149 
HIS O    O  N N 150 
HIS CB   C  N N 151 
HIS CG   C  Y N 152 
HIS ND1  N  Y N 153 
HIS CD2  C  Y N 154 
HIS CE1  C  Y N 155 
HIS NE2  N  Y N 156 
HIS OXT  O  N N 157 
HIS H    H  N N 158 
HIS H2   H  N N 159 
HIS HA   H  N N 160 
HIS HB2  H  N N 161 
HIS HB3  H  N N 162 
HIS HD1  H  N N 163 
HIS HD2  H  N N 164 
HIS HE1  H  N N 165 
HIS HE2  H  N N 166 
HIS HXT  H  N N 167 
HOH O    O  N N 168 
HOH H1   H  N N 169 
HOH H2   H  N N 170 
ILE N    N  N N 171 
ILE CA   C  N S 172 
ILE C    C  N N 173 
ILE O    O  N N 174 
ILE CB   C  N S 175 
ILE CG1  C  N N 176 
ILE CG2  C  N N 177 
ILE CD1  C  N N 178 
ILE OXT  O  N N 179 
ILE H    H  N N 180 
ILE H2   H  N N 181 
ILE HA   H  N N 182 
ILE HB   H  N N 183 
ILE HG12 H  N N 184 
ILE HG13 H  N N 185 
ILE HG21 H  N N 186 
ILE HG22 H  N N 187 
ILE HG23 H  N N 188 
ILE HD11 H  N N 189 
ILE HD12 H  N N 190 
ILE HD13 H  N N 191 
ILE HXT  H  N N 192 
LEU N    N  N N 193 
LEU CA   C  N S 194 
LEU C    C  N N 195 
LEU O    O  N N 196 
LEU CB   C  N N 197 
LEU CG   C  N N 198 
LEU CD1  C  N N 199 
LEU CD2  C  N N 200 
LEU OXT  O  N N 201 
LEU H    H  N N 202 
LEU H2   H  N N 203 
LEU HA   H  N N 204 
LEU HB2  H  N N 205 
LEU HB3  H  N N 206 
LEU HG   H  N N 207 
LEU HD11 H  N N 208 
LEU HD12 H  N N 209 
LEU HD13 H  N N 210 
LEU HD21 H  N N 211 
LEU HD22 H  N N 212 
LEU HD23 H  N N 213 
LEU HXT  H  N N 214 
LYS N    N  N N 215 
LYS CA   C  N S 216 
LYS C    C  N N 217 
LYS O    O  N N 218 
LYS CB   C  N N 219 
LYS CG   C  N N 220 
LYS CD   C  N N 221 
LYS CE   C  N N 222 
LYS NZ   N  N N 223 
LYS OXT  O  N N 224 
LYS H    H  N N 225 
LYS H2   H  N N 226 
LYS HA   H  N N 227 
LYS HB2  H  N N 228 
LYS HB3  H  N N 229 
LYS HG2  H  N N 230 
LYS HG3  H  N N 231 
LYS HD2  H  N N 232 
LYS HD3  H  N N 233 
LYS HE2  H  N N 234 
LYS HE3  H  N N 235 
LYS HZ1  H  N N 236 
LYS HZ2  H  N N 237 
LYS HZ3  H  N N 238 
LYS HXT  H  N N 239 
MET N    N  N N 240 
MET CA   C  N S 241 
MET C    C  N N 242 
MET O    O  N N 243 
MET CB   C  N N 244 
MET CG   C  N N 245 
MET SD   S  N N 246 
MET CE   C  N N 247 
MET OXT  O  N N 248 
MET H    H  N N 249 
MET H2   H  N N 250 
MET HA   H  N N 251 
MET HB2  H  N N 252 
MET HB3  H  N N 253 
MET HG2  H  N N 254 
MET HG3  H  N N 255 
MET HE1  H  N N 256 
MET HE2  H  N N 257 
MET HE3  H  N N 258 
MET HXT  H  N N 259 
MG  MG   MG N N 260 
PEG C1   C  N N 261 
PEG O1   O  N N 262 
PEG C2   C  N N 263 
PEG O2   O  N N 264 
PEG C3   C  N N 265 
PEG C4   C  N N 266 
PEG O4   O  N N 267 
PEG H11  H  N N 268 
PEG H12  H  N N 269 
PEG HO1  H  N N 270 
PEG H21  H  N N 271 
PEG H22  H  N N 272 
PEG H31  H  N N 273 
PEG H32  H  N N 274 
PEG H41  H  N N 275 
PEG H42  H  N N 276 
PEG HO4  H  N N 277 
PHE N    N  N N 278 
PHE CA   C  N S 279 
PHE C    C  N N 280 
PHE O    O  N N 281 
PHE CB   C  N N 282 
PHE CG   C  Y N 283 
PHE CD1  C  Y N 284 
PHE CD2  C  Y N 285 
PHE CE1  C  Y N 286 
PHE CE2  C  Y N 287 
PHE CZ   C  Y N 288 
PHE OXT  O  N N 289 
PHE H    H  N N 290 
PHE H2   H  N N 291 
PHE HA   H  N N 292 
PHE HB2  H  N N 293 
PHE HB3  H  N N 294 
PHE HD1  H  N N 295 
PHE HD2  H  N N 296 
PHE HE1  H  N N 297 
PHE HE2  H  N N 298 
PHE HZ   H  N N 299 
PHE HXT  H  N N 300 
PRO N    N  N N 301 
PRO CA   C  N S 302 
PRO C    C  N N 303 
PRO O    O  N N 304 
PRO CB   C  N N 305 
PRO CG   C  N N 306 
PRO CD   C  N N 307 
PRO OXT  O  N N 308 
PRO H    H  N N 309 
PRO HA   H  N N 310 
PRO HB2  H  N N 311 
PRO HB3  H  N N 312 
PRO HG2  H  N N 313 
PRO HG3  H  N N 314 
PRO HD2  H  N N 315 
PRO HD3  H  N N 316 
PRO HXT  H  N N 317 
SER N    N  N N 318 
SER CA   C  N S 319 
SER C    C  N N 320 
SER O    O  N N 321 
SER CB   C  N N 322 
SER OG   O  N N 323 
SER OXT  O  N N 324 
SER H    H  N N 325 
SER H2   H  N N 326 
SER HA   H  N N 327 
SER HB2  H  N N 328 
SER HB3  H  N N 329 
SER HG   H  N N 330 
SER HXT  H  N N 331 
THR N    N  N N 332 
THR CA   C  N S 333 
THR C    C  N N 334 
THR O    O  N N 335 
THR CB   C  N R 336 
THR OG1  O  N N 337 
THR CG2  C  N N 338 
THR OXT  O  N N 339 
THR H    H  N N 340 
THR H2   H  N N 341 
THR HA   H  N N 342 
THR HB   H  N N 343 
THR HG1  H  N N 344 
THR HG21 H  N N 345 
THR HG22 H  N N 346 
THR HG23 H  N N 347 
THR HXT  H  N N 348 
TRP N    N  N N 349 
TRP CA   C  N S 350 
TRP C    C  N N 351 
TRP O    O  N N 352 
TRP CB   C  N N 353 
TRP CG   C  Y N 354 
TRP CD1  C  Y N 355 
TRP CD2  C  Y N 356 
TRP NE1  N  Y N 357 
TRP CE2  C  Y N 358 
TRP CE3  C  Y N 359 
TRP CZ2  C  Y N 360 
TRP CZ3  C  Y N 361 
TRP CH2  C  Y N 362 
TRP OXT  O  N N 363 
TRP H    H  N N 364 
TRP H2   H  N N 365 
TRP HA   H  N N 366 
TRP HB2  H  N N 367 
TRP HB3  H  N N 368 
TRP HD1  H  N N 369 
TRP HE1  H  N N 370 
TRP HE3  H  N N 371 
TRP HZ2  H  N N 372 
TRP HZ3  H  N N 373 
TRP HH2  H  N N 374 
TRP HXT  H  N N 375 
TYR N    N  N N 376 
TYR CA   C  N S 377 
TYR C    C  N N 378 
TYR O    O  N N 379 
TYR CB   C  N N 380 
TYR CG   C  Y N 381 
TYR CD1  C  Y N 382 
TYR CD2  C  Y N 383 
TYR CE1  C  Y N 384 
TYR CE2  C  Y N 385 
TYR CZ   C  Y N 386 
TYR OH   O  N N 387 
TYR OXT  O  N N 388 
TYR H    H  N N 389 
TYR H2   H  N N 390 
TYR HA   H  N N 391 
TYR HB2  H  N N 392 
TYR HB3  H  N N 393 
TYR HD1  H  N N 394 
TYR HD2  H  N N 395 
TYR HE1  H  N N 396 
TYR HE2  H  N N 397 
TYR HH   H  N N 398 
TYR HXT  H  N N 399 
VAL N    N  N N 400 
VAL CA   C  N S 401 
VAL C    C  N N 402 
VAL O    O  N N 403 
VAL CB   C  N N 404 
VAL CG1  C  N N 405 
VAL CG2  C  N N 406 
VAL OXT  O  N N 407 
VAL H    H  N N 408 
VAL H2   H  N N 409 
VAL HA   H  N N 410 
VAL HB   H  N N 411 
VAL HG11 H  N N 412 
VAL HG12 H  N N 413 
VAL HG13 H  N N 414 
VAL HG21 H  N N 415 
VAL HG22 H  N N 416 
VAL HG23 H  N N 417 
VAL HXT  H  N N 418 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EDO C1  O1   sing N N 83  
EDO C1  C2   sing N N 84  
EDO C1  H11  sing N N 85  
EDO C1  H12  sing N N 86  
EDO O1  HO1  sing N N 87  
EDO C2  O2   sing N N 88  
EDO C2  H21  sing N N 89  
EDO C2  H22  sing N N 90  
EDO O2  HO2  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
HIS N   CA   sing N N 138 
HIS N   H    sing N N 139 
HIS N   H2   sing N N 140 
HIS CA  C    sing N N 141 
HIS CA  CB   sing N N 142 
HIS CA  HA   sing N N 143 
HIS C   O    doub N N 144 
HIS C   OXT  sing N N 145 
HIS CB  CG   sing N N 146 
HIS CB  HB2  sing N N 147 
HIS CB  HB3  sing N N 148 
HIS CG  ND1  sing Y N 149 
HIS CG  CD2  doub Y N 150 
HIS ND1 CE1  doub Y N 151 
HIS ND1 HD1  sing N N 152 
HIS CD2 NE2  sing Y N 153 
HIS CD2 HD2  sing N N 154 
HIS CE1 NE2  sing Y N 155 
HIS CE1 HE1  sing N N 156 
HIS NE2 HE2  sing N N 157 
HIS OXT HXT  sing N N 158 
HOH O   H1   sing N N 159 
HOH O   H2   sing N N 160 
ILE N   CA   sing N N 161 
ILE N   H    sing N N 162 
ILE N   H2   sing N N 163 
ILE CA  C    sing N N 164 
ILE CA  CB   sing N N 165 
ILE CA  HA   sing N N 166 
ILE C   O    doub N N 167 
ILE C   OXT  sing N N 168 
ILE CB  CG1  sing N N 169 
ILE CB  CG2  sing N N 170 
ILE CB  HB   sing N N 171 
ILE CG1 CD1  sing N N 172 
ILE CG1 HG12 sing N N 173 
ILE CG1 HG13 sing N N 174 
ILE CG2 HG21 sing N N 175 
ILE CG2 HG22 sing N N 176 
ILE CG2 HG23 sing N N 177 
ILE CD1 HD11 sing N N 178 
ILE CD1 HD12 sing N N 179 
ILE CD1 HD13 sing N N 180 
ILE OXT HXT  sing N N 181 
LEU N   CA   sing N N 182 
LEU N   H    sing N N 183 
LEU N   H2   sing N N 184 
LEU CA  C    sing N N 185 
LEU CA  CB   sing N N 186 
LEU CA  HA   sing N N 187 
LEU C   O    doub N N 188 
LEU C   OXT  sing N N 189 
LEU CB  CG   sing N N 190 
LEU CB  HB2  sing N N 191 
LEU CB  HB3  sing N N 192 
LEU CG  CD1  sing N N 193 
LEU CG  CD2  sing N N 194 
LEU CG  HG   sing N N 195 
LEU CD1 HD11 sing N N 196 
LEU CD1 HD12 sing N N 197 
LEU CD1 HD13 sing N N 198 
LEU CD2 HD21 sing N N 199 
LEU CD2 HD22 sing N N 200 
LEU CD2 HD23 sing N N 201 
LEU OXT HXT  sing N N 202 
LYS N   CA   sing N N 203 
LYS N   H    sing N N 204 
LYS N   H2   sing N N 205 
LYS CA  C    sing N N 206 
LYS CA  CB   sing N N 207 
LYS CA  HA   sing N N 208 
LYS C   O    doub N N 209 
LYS C   OXT  sing N N 210 
LYS CB  CG   sing N N 211 
LYS CB  HB2  sing N N 212 
LYS CB  HB3  sing N N 213 
LYS CG  CD   sing N N 214 
LYS CG  HG2  sing N N 215 
LYS CG  HG3  sing N N 216 
LYS CD  CE   sing N N 217 
LYS CD  HD2  sing N N 218 
LYS CD  HD3  sing N N 219 
LYS CE  NZ   sing N N 220 
LYS CE  HE2  sing N N 221 
LYS CE  HE3  sing N N 222 
LYS NZ  HZ1  sing N N 223 
LYS NZ  HZ2  sing N N 224 
LYS NZ  HZ3  sing N N 225 
LYS OXT HXT  sing N N 226 
MET N   CA   sing N N 227 
MET N   H    sing N N 228 
MET N   H2   sing N N 229 
MET CA  C    sing N N 230 
MET CA  CB   sing N N 231 
MET CA  HA   sing N N 232 
MET C   O    doub N N 233 
MET C   OXT  sing N N 234 
MET CB  CG   sing N N 235 
MET CB  HB2  sing N N 236 
MET CB  HB3  sing N N 237 
MET CG  SD   sing N N 238 
MET CG  HG2  sing N N 239 
MET CG  HG3  sing N N 240 
MET SD  CE   sing N N 241 
MET CE  HE1  sing N N 242 
MET CE  HE2  sing N N 243 
MET CE  HE3  sing N N 244 
MET OXT HXT  sing N N 245 
PEG C1  O1   sing N N 246 
PEG C1  C2   sing N N 247 
PEG C1  H11  sing N N 248 
PEG C1  H12  sing N N 249 
PEG O1  HO1  sing N N 250 
PEG C2  O2   sing N N 251 
PEG C2  H21  sing N N 252 
PEG C2  H22  sing N N 253 
PEG O2  C3   sing N N 254 
PEG C3  C4   sing N N 255 
PEG C3  H31  sing N N 256 
PEG C3  H32  sing N N 257 
PEG C4  O4   sing N N 258 
PEG C4  H41  sing N N 259 
PEG C4  H42  sing N N 260 
PEG O4  HO4  sing N N 261 
PHE N   CA   sing N N 262 
PHE N   H    sing N N 263 
PHE N   H2   sing N N 264 
PHE CA  C    sing N N 265 
PHE CA  CB   sing N N 266 
PHE CA  HA   sing N N 267 
PHE C   O    doub N N 268 
PHE C   OXT  sing N N 269 
PHE CB  CG   sing N N 270 
PHE CB  HB2  sing N N 271 
PHE CB  HB3  sing N N 272 
PHE CG  CD1  doub Y N 273 
PHE CG  CD2  sing Y N 274 
PHE CD1 CE1  sing Y N 275 
PHE CD1 HD1  sing N N 276 
PHE CD2 CE2  doub Y N 277 
PHE CD2 HD2  sing N N 278 
PHE CE1 CZ   doub Y N 279 
PHE CE1 HE1  sing N N 280 
PHE CE2 CZ   sing Y N 281 
PHE CE2 HE2  sing N N 282 
PHE CZ  HZ   sing N N 283 
PHE OXT HXT  sing N N 284 
PRO N   CA   sing N N 285 
PRO N   CD   sing N N 286 
PRO N   H    sing N N 287 
PRO CA  C    sing N N 288 
PRO CA  CB   sing N N 289 
PRO CA  HA   sing N N 290 
PRO C   O    doub N N 291 
PRO C   OXT  sing N N 292 
PRO CB  CG   sing N N 293 
PRO CB  HB2  sing N N 294 
PRO CB  HB3  sing N N 295 
PRO CG  CD   sing N N 296 
PRO CG  HG2  sing N N 297 
PRO CG  HG3  sing N N 298 
PRO CD  HD2  sing N N 299 
PRO CD  HD3  sing N N 300 
PRO OXT HXT  sing N N 301 
SER N   CA   sing N N 302 
SER N   H    sing N N 303 
SER N   H2   sing N N 304 
SER CA  C    sing N N 305 
SER CA  CB   sing N N 306 
SER CA  HA   sing N N 307 
SER C   O    doub N N 308 
SER C   OXT  sing N N 309 
SER CB  OG   sing N N 310 
SER CB  HB2  sing N N 311 
SER CB  HB3  sing N N 312 
SER OG  HG   sing N N 313 
SER OXT HXT  sing N N 314 
THR N   CA   sing N N 315 
THR N   H    sing N N 316 
THR N   H2   sing N N 317 
THR CA  C    sing N N 318 
THR CA  CB   sing N N 319 
THR CA  HA   sing N N 320 
THR C   O    doub N N 321 
THR C   OXT  sing N N 322 
THR CB  OG1  sing N N 323 
THR CB  CG2  sing N N 324 
THR CB  HB   sing N N 325 
THR OG1 HG1  sing N N 326 
THR CG2 HG21 sing N N 327 
THR CG2 HG22 sing N N 328 
THR CG2 HG23 sing N N 329 
THR OXT HXT  sing N N 330 
TRP N   CA   sing N N 331 
TRP N   H    sing N N 332 
TRP N   H2   sing N N 333 
TRP CA  C    sing N N 334 
TRP CA  CB   sing N N 335 
TRP CA  HA   sing N N 336 
TRP C   O    doub N N 337 
TRP C   OXT  sing N N 338 
TRP CB  CG   sing N N 339 
TRP CB  HB2  sing N N 340 
TRP CB  HB3  sing N N 341 
TRP CG  CD1  doub Y N 342 
TRP CG  CD2  sing Y N 343 
TRP CD1 NE1  sing Y N 344 
TRP CD1 HD1  sing N N 345 
TRP CD2 CE2  doub Y N 346 
TRP CD2 CE3  sing Y N 347 
TRP NE1 CE2  sing Y N 348 
TRP NE1 HE1  sing N N 349 
TRP CE2 CZ2  sing Y N 350 
TRP CE3 CZ3  doub Y N 351 
TRP CE3 HE3  sing N N 352 
TRP CZ2 CH2  doub Y N 353 
TRP CZ2 HZ2  sing N N 354 
TRP CZ3 CH2  sing Y N 355 
TRP CZ3 HZ3  sing N N 356 
TRP CH2 HH2  sing N N 357 
TRP OXT HXT  sing N N 358 
TYR N   CA   sing N N 359 
TYR N   H    sing N N 360 
TYR N   H2   sing N N 361 
TYR CA  C    sing N N 362 
TYR CA  CB   sing N N 363 
TYR CA  HA   sing N N 364 
TYR C   O    doub N N 365 
TYR C   OXT  sing N N 366 
TYR CB  CG   sing N N 367 
TYR CB  HB2  sing N N 368 
TYR CB  HB3  sing N N 369 
TYR CG  CD1  doub Y N 370 
TYR CG  CD2  sing Y N 371 
TYR CD1 CE1  sing Y N 372 
TYR CD1 HD1  sing N N 373 
TYR CD2 CE2  doub Y N 374 
TYR CD2 HD2  sing N N 375 
TYR CE1 CZ   doub Y N 376 
TYR CE1 HE1  sing N N 377 
TYR CE2 CZ   sing Y N 378 
TYR CE2 HE2  sing N N 379 
TYR CZ  OH   sing N N 380 
TYR OH  HH   sing N N 381 
TYR OXT HXT  sing N N 382 
VAL N   CA   sing N N 383 
VAL N   H    sing N N 384 
VAL N   H2   sing N N 385 
VAL CA  C    sing N N 386 
VAL CA  CB   sing N N 387 
VAL CA  HA   sing N N 388 
VAL C   O    doub N N 389 
VAL C   OXT  sing N N 390 
VAL CB  CG1  sing N N 391 
VAL CB  CG2  sing N N 392 
VAL CB  HB   sing N N 393 
VAL CG1 HG11 sing N N 394 
VAL CG1 HG12 sing N N 395 
VAL CG1 HG13 sing N N 396 
VAL CG2 HG21 sing N N 397 
VAL CG2 HG22 sing N N 398 
VAL CG2 HG23 sing N N 399 
VAL OXT HXT  sing N N 400 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   1ow0 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9R2E 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012938 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000079 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.004305 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.009477 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . GLU A 1 20  ? 5.432   39.575  25.756 1   51.01  ? 2   GLU H N   1 
ATOM   2     C  CA  . GLU A 1 20  ? 6.932   39.493  25.787 1   50.51  ? 2   GLU H CA  1 
ATOM   3     C  C   . GLU A 1 20  ? 7.397   38.802  27.076 1   48.05  ? 2   GLU H C   1 
ATOM   4     O  O   . GLU A 1 20  ? 6.734   38.966  28.117 1   47.02  ? 2   GLU H O   1 
ATOM   5     C  CB  . GLU A 1 20  ? 7.57    40.885  25.677 1   51.93  ? 2   GLU H CB  1 
ATOM   6     C  CG  . GLU A 1 20  ? 7.766   41.365  24.246 1   51.87  ? 2   GLU H CG  1 
ATOM   7     C  CD  . GLU A 1 20  ? 6.534   41.852  23.493 1   52.75  ? 2   GLU H CD  1 
ATOM   8     O  OE1 . GLU A 1 20  ? 6.713   42.33   22.356 1   51.43  ? 2   GLU H OE1 1 
ATOM   9     O  OE2 . GLU A 1 20  ? 5.402   41.756  24.031 1   51.36  ? 2   GLU H OE2 1 
ATOM   10    N  N   . VAL A 1 21  ? 8.513   38.071  27     1   46.12  ? 3   VAL H N   1 
ATOM   11    C  CA  . VAL A 1 21  ? 9.227   37.508  28.183 1   43.99  ? 3   VAL H CA  1 
ATOM   12    C  C   . VAL A 1 21  ? 9.754   38.683  29.012 1   45.46  ? 3   VAL H C   1 
ATOM   13    O  O   . VAL A 1 21  ? 10.414  39.561  28.434 1   47.38  ? 3   VAL H O   1 
ATOM   14    C  CB  . VAL A 1 21  ? 10.364  36.558  27.766 1   42.26  ? 3   VAL H CB  1 
ATOM   15    C  CG1 . VAL A 1 21  ? 11.26   36.192  28.942 1   42.43  ? 3   VAL H CG1 1 
ATOM   16    C  CG2 . VAL A 1 21  ? 9.823   35.303  27.099 1   41.71  ? 3   VAL H CG2 1 
ATOM   17    N  N   . GLN A 1 22  ? 9.456   38.696  30.31  1   47.18  ? 4   GLN H N   1 
ATOM   18    C  CA  . GLN A 1 22  ? 9.98    39.696  31.274 1   48.26  ? 4   GLN H CA  1 
ATOM   19    C  C   . GLN A 1 22  ? 10.328  38.974  32.576 1   45.99  ? 4   GLN H C   1 
ATOM   20    O  O   . GLN A 1 22  ? 9.572   38.061  32.969 1   44.07  ? 4   GLN H O   1 
ATOM   21    C  CB  . GLN A 1 22  ? 8.964   40.812  31.515 1   53.96  ? 4   GLN H CB  1 
ATOM   22    C  CG  . GLN A 1 22  ? 9.537   41.997  32.28  1   60.52  ? 4   GLN H CG  1 
ATOM   23    C  CD  . GLN A 1 22  ? 8.497   43.043  32.605 1   67.94  ? 4   GLN H CD  1 
ATOM   24    O  OE1 . GLN A 1 22  ? 8.256   43.361  33.77  1   71.53  ? 4   GLN H OE1 1 
ATOM   25    N  NE2 . GLN A 1 22  ? 7.869   43.588  31.573 1   68.69  ? 4   GLN H NE2 1 
ATOM   26    N  N   . LEU A 1 23  ? 11.435  39.386  33.2   1   45.66  ? 5   LEU H N   1 
ATOM   27    C  CA  . LEU A 1 23  ? 11.961  38.859  34.485 1   44.94  ? 5   LEU H CA  1 
ATOM   28    C  C   . LEU A 1 23  ? 12.294  40.051  35.391 1   44.99  ? 5   LEU H C   1 
ATOM   29    O  O   . LEU A 1 23  ? 13.085  40.907  34.946 1   46.33  ? 5   LEU H O   1 
ATOM   30    C  CB  . LEU A 1 23  ? 13.2    38.014  34.174 1   45.64  ? 5   LEU H CB  1 
ATOM   31    C  CG  . LEU A 1 23  ? 12.94   36.728  33.386 1   45.67  ? 5   LEU H CG  1 
ATOM   32    C  CD1 . LEU A 1 23  ? 14.022  36.479  32.352 1   46.89  ? 5   LEU H CD1 1 
ATOM   33    C  CD2 . LEU A 1 23  ? 12.814  35.535  34.316 1   46.88  ? 5   LEU H CD2 1 
ATOM   34    N  N   . LEU A 1 24  ? 11.678  40.132  36.578 1   45.27  ? 6   LEU H N   1 
ATOM   35    C  CA  . LEU A 1 24  ? 11.898  41.219  37.574 1   45.65  ? 6   LEU H CA  1 
ATOM   36    C  C   . LEU A 1 24  ? 12.511  40.628  38.845 1   44.21  ? 6   LEU H C   1 
ATOM   37    O  O   . LEU A 1 24  ? 11.755  40.04   39.642 1   45.53  ? 6   LEU H O   1 
ATOM   38    C  CB  . LEU A 1 24  ? 10.572  41.911  37.912 1   49.49  ? 6   LEU H CB  1 
ATOM   39    C  CG  . LEU A 1 24  ? 10.122  43.057  37.008 1   54.44  ? 6   LEU H CG  1 
ATOM   40    C  CD1 . LEU A 1 24  ? 8.858   43.693  37.572 1   55.64  ? 6   LEU H CD1 1 
ATOM   41    C  CD2 . LEU A 1 24  ? 11.201  44.119  36.842 1   56.9   ? 6   LEU H CD2 1 
ATOM   42    N  N   . GLU A 1 25  ? 13.819  40.812  39.034 1   43.55  ? 7   GLU H N   1 
ATOM   43    C  CA  . GLU A 1 25  ? 14.529  40.449  40.285 1   43.07  ? 7   GLU H CA  1 
ATOM   44    C  C   . GLU A 1 25  ? 14.136  41.453  41.367 1   43.74  ? 7   GLU H C   1 
ATOM   45    O  O   . GLU A 1 25  ? 13.965  42.635  41.024 1   46.35  ? 7   GLU H O   1 
ATOM   46    C  CB  . GLU A 1 25  ? 16.049  40.48   40.125 1   44.33  ? 7   GLU H CB  1 
ATOM   47    C  CG  . GLU A 1 25  ? 16.592  39.465  39.139 1   45.33  ? 7   GLU H CG  1 
ATOM   48    C  CD  . GLU A 1 25  ? 16.678  39.935  37.698 1   45.98  ? 7   GLU H CD  1 
ATOM   49    O  OE1 . GLU A 1 25  ? 16.081  40.983  37.374 1   46.51  ? 7   GLU H OE1 1 
ATOM   50    O  OE2 . GLU A 1 25  ? 17.355  39.261  36.901 1   46.73  ? 7   GLU H OE2 1 
ATOM   51    N  N   . SER A 1 26  ? 14.011  40.993  42.615 1   44.81  ? 8   SER H N   1 
ATOM   52    C  CA  . SER A 1 26  ? 13.874  41.838  43.832 1   46.93  ? 8   SER H CA  1 
ATOM   53    C  C   . SER A 1 26  ? 14.545  41.149  45.028 1   47.15  ? 8   SER H C   1 
ATOM   54    O  O   . SER A 1 26  ? 14.876  39.948  44.915 1   47.64  ? 8   SER H O   1 
ATOM   55    C  CB  . SER A 1 26  ? 12.426  42.152  44.117 1   48.31  ? 8   SER H CB  1 
ATOM   56    O  OG  . SER A 1 26  ? 11.671  40.955  44.239 1   52.78  ? 8   SER H OG  1 
ATOM   57    N  N   . GLY A 1 27  ? 14.742  41.89   46.124 1   45.88  ? 9   GLY H N   1 
ATOM   58    C  CA  . GLY A 1 27  ? 15.248  41.37   47.409 1   45.4   ? 9   GLY H CA  1 
ATOM   59    C  C   . GLY A 1 27  ? 16.669  41.817  47.7   1   46.34  ? 9   GLY H C   1 
ATOM   60    O  O   . GLY A 1 27  ? 17.092  41.677  48.865 1   49.3   ? 9   GLY H O   1 
ATOM   61    N  N   . GLY A 1 28  ? 17.396  42.32   46.695 1   45.64  ? 10  GLY H N   1 
ATOM   62    C  CA  . GLY A 1 28  ? 18.771  42.825  46.867 1   46.1   ? 10  GLY H CA  1 
ATOM   63    C  C   . GLY A 1 28  ? 18.833  43.958  47.879 1   46.37  ? 10  GLY H C   1 
ATOM   64    O  O   . GLY A 1 28  ? 17.858  44.72   47.985 1   49.98  ? 10  GLY H O   1 
ATOM   65    N  N   . GLY A 1 29  ? 19.94   44.057  48.609 1   45.73  ? 11  GLY H N   1 
ATOM   66    C  CA  . GLY A 1 29  ? 20.178  45.127  49.59  1   46.12  ? 11  GLY H CA  1 
ATOM   67    C  C   . GLY A 1 29  ? 21.344  44.794  50.496 1   48.12  ? 11  GLY H C   1 
ATOM   68    O  O   . GLY A 1 29  ? 22.169  43.931  50.113 1   47.56  ? 11  GLY H O   1 
ATOM   69    N  N   . LEU A 1 30  ? 21.417  45.466  51.648 1   50.53  ? 12  LEU H N   1 
ATOM   70    C  CA  . LEU A 1 30  ? 22.485  45.252  52.653 1   54.29  ? 12  LEU H CA  1 
ATOM   71    C  C   . LEU A 1 30  ? 22.155  43.99   53.451 1   55.06  ? 12  LEU H C   1 
ATOM   72    O  O   . LEU A 1 30  ? 20.966  43.76   53.746 1   57.08  ? 12  LEU H O   1 
ATOM   73    C  CB  . LEU A 1 30  ? 22.606  46.471  53.571 1   56.54  ? 12  LEU H CB  1 
ATOM   74    C  CG  . LEU A 1 30  ? 23.712  46.389  54.624 1   60.4   ? 12  LEU H CG  1 
ATOM   75    C  CD1 . LEU A 1 30  ? 25.087  46.273  53.983 1   60.51  ? 12  LEU H CD1 1 
ATOM   76    C  CD2 . LEU A 1 30  ? 23.667  47.595  55.547 1   63.39  ? 12  LEU H CD2 1 
ATOM   77    N  N   . VAL A 1 31  ? 23.179  43.207  53.777 1   54.78  ? 13  VAL H N   1 
ATOM   78    C  CA  . VAL A 1 31  ? 23.06   41.998  54.638 1   57.89  ? 13  VAL H CA  1 
ATOM   79    C  C   . VAL A 1 31  ? 24.416  41.784  55.316 1   59.27  ? 13  VAL H C   1 
ATOM   80    O  O   . VAL A 1 31  ? 25.438  41.888  54.612 1   60.42  ? 13  VAL H O   1 
ATOM   81    C  CB  . VAL A 1 31  ? 22.574  40.789  53.812 1   60.08  ? 13  VAL H CB  1 
ATOM   82    C  CG1 . VAL A 1 31  ? 23.521  40.43   52.675 1   59.57  ? 13  VAL H CG1 1 
ATOM   83    C  CG2 . VAL A 1 31  ? 22.288  39.578  54.686 1   63.51  ? 13  VAL H CG2 1 
ATOM   84    N  N   . GLN A 1 32  ? 24.428  41.563  56.636 1   61.34  ? 14  GLN H N   1 
ATOM   85    C  CA  . GLN A 1 32  ? 25.676  41.505  57.452 1   62.63  ? 14  GLN H CA  1 
ATOM   86    C  C   . GLN A 1 32  ? 26.395  40.188  57.148 1   58.97  ? 14  GLN H C   1 
ATOM   87    O  O   . GLN A 1 32  ? 25.739  39.197  56.821 1   57.56  ? 14  GLN H O   1 
ATOM   88    C  CB  . GLN A 1 32  ? 25.369  41.671  58.946 1   67.87  ? 14  GLN H CB  1 
ATOM   89    C  CG  . GLN A 1 32  ? 24.672  42.983  59.306 1   73.01  ? 14  GLN H CG  1 
ATOM   90    C  CD  . GLN A 1 32  ? 25.55   44.203  59.13  1   78.31  ? 14  GLN H CD  1 
ATOM   91    O  OE1 . GLN A 1 32  ? 26.539  44.383  59.839 1   82.67  ? 14  GLN H OE1 1 
ATOM   92    N  NE2 . GLN A 1 32  ? 25.195  45.067  58.189 1   77.97  ? 14  GLN H NE2 1 
ATOM   93    N  N   . PRO A 1 33  ? 27.75   40.13   57.197 1   53.66  ? 15  PRO H N   1 
ATOM   94    C  CA  . PRO A 1 33  ? 28.476  38.89   56.915 1   55.4   ? 15  PRO H CA  1 
ATOM   95    C  C   . PRO A 1 33  ? 28.035  37.745  57.84  1   56.38  ? 15  PRO H C   1 
ATOM   96    O  O   . PRO A 1 33  ? 28.034  37.938  59.04  1   58.09  ? 15  PRO H O   1 
ATOM   97    C  CB  . PRO A 1 33  ? 29.952  39.254  57.146 1   54.83  ? 15  PRO H CB  1 
ATOM   98    C  CG  . PRO A 1 33  ? 29.995  40.753  56.956 1   53.17  ? 15  PRO H CG  1 
ATOM   99    C  CD  . PRO A 1 33  ? 28.664  41.244  57.486 1   53.05  ? 15  PRO H CD  1 
ATOM   100   N  N   . GLY A 1 34  ? 27.641  36.612  57.249 1   55.63  ? 16  GLY H N   1 
ATOM   101   C  CA  . GLY A 1 34  ? 27.05   35.455  57.948 1   56.37  ? 16  GLY H CA  1 
ATOM   102   C  C   . GLY A 1 34  ? 25.534  35.461  57.876 1   57.29  ? 16  GLY H C   1 
ATOM   103   O  O   . GLY A 1 34  ? 24.927  34.415  58.19  1   58.07  ? 16  GLY H O   1 
ATOM   104   N  N   . GLY A 1 35  ? 24.932  36.583  57.466 1   58.16  ? 17  GLY H N   1 
ATOM   105   C  CA  . GLY A 1 35  ? 23.469  36.762  57.411 1   60.23  ? 17  GLY H CA  1 
ATOM   106   C  C   . GLY A 1 35  ? 22.842  36.003  56.256 1   58.93  ? 17  GLY H C   1 
ATOM   107   O  O   . GLY A 1 35  ? 23.594  35.473  55.411 1   63.14  ? 17  GLY H O   1 
ATOM   108   N  N   . SER A 1 36  ? 21.508  35.952  56.227 1   55.5   ? 18  SER H N   1 
ATOM   109   C  CA  . SER A 1 36  ? 20.704  35.322  55.152 1   55.9   ? 18  SER H CA  1 
ATOM   110   C  C   . SER A 1 36  ? 19.985  36.407  54.339 1   55.01  ? 18  SER H C   1 
ATOM   111   O  O   . SER A 1 36  ? 19.834  37.534  54.84  1   57.78  ? 18  SER H O   1 
ATOM   112   C  CB  . SER A 1 36  ? 19.739  34.307  55.715 1   58.38  ? 18  SER H CB  1 
ATOM   113   O  OG  . SER A 1 36  ? 18.661  34.936  56.393 1   63.09  ? 18  SER H OG  1 
ATOM   114   N  N   . LEU A 1 37  ? 19.571  36.069  53.119 1   55.72  ? 19  LEU H N   1 
ATOM   115   C  CA  . LEU A 1 37  ? 18.788  36.953  52.216 1   55.72  ? 19  LEU H CA  1 
ATOM   116   C  C   . LEU A 1 37  ? 18.127  36.098  51.13  1   54.07  ? 19  LEU H C   1 
ATOM   117   O  O   . LEU A 1 37  ? 18.814  35.223  50.582 1   56.87  ? 19  LEU H O   1 
ATOM   118   C  CB  . LEU A 1 37  ? 19.726  37.999  51.608 1   58.12  ? 19  LEU H CB  1 
ATOM   119   C  CG  . LEU A 1 37  ? 19.043  39.12   50.826 1   58.55  ? 19  LEU H CG  1 
ATOM   120   C  CD1 . LEU A 1 37  ? 19.412  40.482  51.39  1   59.96  ? 19  LEU H CD1 1 
ATOM   121   C  CD2 . LEU A 1 37  ? 19.387  39.042  49.347 1   59.27  ? 19  LEU H CD2 1 
ATOM   122   N  N   . ARG A 1 38  ? 16.843  36.337  50.864 1   51.41  ? 20  ARG H N   1 
ATOM   123   C  CA  . ARG A 1 38  ? 16.04   35.649  49.822 1   52.6   ? 20  ARG H CA  1 
ATOM   124   C  C   . ARG A 1 38  ? 15.832  36.636  48.669 1   51.98  ? 20  ARG H C   1 
ATOM   125   O  O   . ARG A 1 38  ? 15.301  37.738  48.927 1   54.11  ? 20  ARG H O   1 
ATOM   126   C  CB  . ARG A 1 38  ? 14.716  35.168  50.43  1   57.11  ? 20  ARG H CB  1 
ATOM   127   C  CG  . ARG A 1 38  ? 13.728  34.547  49.449 1   59.22  ? 20  ARG H CG  1 
ATOM   128   C  CD  . ARG A 1 38  ? 12.852  33.503  50.125 1   63.23  ? 20  ARG H CD  1 
ATOM   129   N  NE  . ARG A 1 38  ? 11.502  33.37   49.586 1   65.81  ? 20  ARG H NE  1 
ATOM   130   C  CZ  . ARG A 1 38  ? 10.509  34.249  49.753 1   71.18  ? 20  ARG H CZ  1 
ATOM   131   N  NH1 . ARG A 1 38  ? 10.702  35.38   50.416 1   75.05  ? 20  ARG H NH1 1 
ATOM   132   N  NH2 . ARG A 1 38  ? 9.317   33.999  49.235 1   71.8   ? 20  ARG H NH2 1 
ATOM   133   N  N   . LEU A 1 39  ? 16.274  36.269  47.463 1   48.78  ? 21  LEU H N   1 
ATOM   134   C  CA  . LEU A 1 39  ? 15.975  37      46.202 1   44.95  ? 21  LEU H CA  1 
ATOM   135   C  C   . LEU A 1 39  ? 14.754  36.355  45.548 1   41.3   ? 21  LEU H C   1 
ATOM   136   O  O   . LEU A 1 39  ? 14.606  35.14   45.67  1   40.95  ? 21  LEU H O   1 
ATOM   137   C  CB  . LEU A 1 39  ? 17.2    36.957  45.284 1   43.28  ? 21  LEU H CB  1 
ATOM   138   C  CG  . LEU A 1 39  ? 18.467  37.579  45.866 1   43.95  ? 21  LEU H CG  1 
ATOM   139   C  CD1 . LEU A 1 39  ? 19.648  37.387  44.926 1   44.89  ? 21  LEU H CD1 1 
ATOM   140   C  CD2 . LEU A 1 39  ? 18.265  39.056  46.167 1   43.07  ? 21  LEU H CD2 1 
ATOM   141   N  N   . SER A 1 40  ? 13.898  37.164  44.926 1   40.94  ? 22  SER H N   1 
ATOM   142   C  CA  . SER A 1 40  ? 12.724  36.73   44.126 1   40.48  ? 22  SER H CA  1 
ATOM   143   C  C   . SER A 1 40  ? 12.941  37.137  42.672 1   39.19  ? 22  SER H C   1 
ATOM   144   O  O   . SER A 1 40  ? 13.7    38.079  42.429 1   38.66  ? 22  SER H O   1 
ATOM   145   C  CB  . SER A 1 40  ? 11.452  37.321  44.653 1   40.45  ? 22  SER H CB  1 
ATOM   146   O  OG  . SER A 1 40  ? 11.311  37.042  46.033 1   44     ? 22  SER H OG  1 
ATOM   147   N  N   . CYS A 1 41  ? 12.28   36.446  41.751 1   39.83  ? 23  CYS H N   1 
ATOM   148   C  CA  . CYS A 1 41  ? 12.312  36.736  40.299 1   41.4   ? 23  CYS H CA  1 
ATOM   149   C  C   . CYS A 1 41  ? 10.922  36.481  39.725 1   39.43  ? 23  CYS H C   1 
ATOM   150   O  O   . CYS A 1 41  ? 10.611  35.316  39.481 1   36.91  ? 23  CYS H O   1 
ATOM   151   C  CB  . CYS A 1 41  ? 13.36   35.886  39.594 1   45.31  ? 23  CYS H CB  1 
ATOM   152   S  SG  . CYS A 1 41  ? 13.274  36.002  37.788 1   50.1   ? 23  CYS H SG  1 
ATOM   153   N  N   . ALA A 1 42  ? 10.134  37.542  39.54  1   39.8   ? 24  ALA H N   1 
ATOM   154   C  CA  . ALA A 1 42  ? 8.776   37.49   38.953 1   40.25  ? 24  ALA H CA  1 
ATOM   155   C  C   . ALA A 1 42  ? 8.899   37.319  37.433 1   39.37  ? 24  ALA H C   1 
ATOM   156   O  O   . ALA A 1 42  ? 9.402   38.251  36.766 1   41.36  ? 24  ALA H O   1 
ATOM   157   C  CB  . ALA A 1 42  ? 7.989   38.728  39.324 1   40.04  ? 24  ALA H CB  1 
ATOM   158   N  N   . ALA A 1 43  ? 8.48    36.16   36.921 1   38.01  ? 25  ALA H N   1 
ATOM   159   C  CA  . ALA A 1 43  ? 8.415   35.837  35.476 1   39.38  ? 25  ALA H CA  1 
ATOM   160   C  C   . ALA A 1 43  ? 7.045   36.259  34.942 1   39.9   ? 25  ALA H C   1 
ATOM   161   O  O   . ALA A 1 43  ? 6.067   36.195  35.714 1   42.19  ? 25  ALA H O   1 
ATOM   162   C  CB  . ALA A 1 43  ? 8.662   34.362  35.251 1   38.75  ? 25  ALA H CB  1 
ATOM   163   N  N   . SER A 1 44  ? 6.984   36.688  33.68  1   39.76  ? 26  SER H N   1 
ATOM   164   C  CA  . SER A 1 44  ? 5.721   36.967  32.949 1   41.43  ? 26  SER H CA  1 
ATOM   165   C  C   . SER A 1 44  ? 5.946   36.803  31.443 1   41.91  ? 26  SER H C   1 
ATOM   166   O  O   . SER A 1 44  ? 7.097   36.966  30.991 1   39.39  ? 26  SER H O   1 
ATOM   167   C  CB  . SER A 1 44  ? 5.156   38.331  33.296 1   43.24  ? 26  SER H CB  1 
ATOM   168   O  OG  . SER A 1 44  ? 6.027   39.385  32.906 1   44.47  ? 26  SER H OG  1 
ATOM   169   N  N   . GLY A 1 45  ? 4.877   36.47   30.714 1   43.97  ? 27  GLY H N   1 
ATOM   170   C  CA  . GLY A 1 45  ? 4.909   36.188  29.267 1   46.08  ? 27  GLY H CA  1 
ATOM   171   C  C   . GLY A 1 45  ? 5.515   34.829  28.944 1   47.86  ? 27  GLY H C   1 
ATOM   172   O  O   . GLY A 1 45  ? 5.811   34.603  27.756 1   53.85  ? 27  GLY H O   1 
ATOM   173   N  N   . PHE A 1 46  ? 5.695   33.961  29.951 1   45.4   ? 28  PHE H N   1 
ATOM   174   C  CA  . PHE A 1 46  ? 6.095   32.532  29.832 1   43.22  ? 28  PHE H CA  1 
ATOM   175   C  C   . PHE A 1 46  ? 5.909   31.876  31.207 1   43.77  ? 28  PHE H C   1 
ATOM   176   O  O   . PHE A 1 46  ? 5.896   32.614  32.219 1   42.96  ? 28  PHE H O   1 
ATOM   177   C  CB  . PHE A 1 46  ? 7.538   32.391  29.331 1   42.65  ? 28  PHE H CB  1 
ATOM   178   C  CG  . PHE A 1 46  ? 8.591   32.649  30.382 1   43.97  ? 28  PHE H CG  1 
ATOM   179   C  CD1 . PHE A 1 46  ? 8.869   33.941  30.814 1   43.58  ? 28  PHE H CD1 1 
ATOM   180   C  CD2 . PHE A 1 46  ? 9.286   31.598  30.965 1   43.29  ? 28  PHE H CD2 1 
ATOM   181   C  CE1 . PHE A 1 46  ? 9.825   34.174  31.793 1   42.41  ? 28  PHE H CE1 1 
ATOM   182   C  CE2 . PHE A 1 46  ? 10.24   31.835  31.944 1   42.33  ? 28  PHE H CE2 1 
ATOM   183   C  CZ  . PHE A 1 46  ? 10.505  33.119  32.359 1   41.97  ? 28  PHE H CZ  1 
ATOM   184   N  N   . THR A 1 47  ? 5.78    30.547  31.25  1   44.03  ? 29  THR H N   1 
ATOM   185   C  CA  . THR A 1 47  ? 5.652   29.758  32.505 1   44.79  ? 29  THR H CA  1 
ATOM   186   C  C   . THR A 1 47  ? 7.05    29.286  32.917 1   46.58  ? 29  THR H C   1 
ATOM   187   O  O   . THR A 1 47  ? 7.603   28.419  32.214 1   49.49  ? 29  THR H O   1 
ATOM   188   C  CB  . THR A 1 47  ? 4.657   28.602  32.333 1   44.91  ? 29  THR H CB  1 
ATOM   189   O  OG1 . THR A 1 47  ? 3.48    29.132  31.724 1   44.98  ? 29  THR H OG1 1 
ATOM   190   C  CG2 . THR A 1 47  ? 4.292   27.929  33.639 1   43.95  ? 29  THR H CG2 1 
ATOM   191   N  N   . SER A 1 48  ? 7.587   29.817  34.023 1   45.71  ? 30  SER H N   1 
ATOM   192   C  CA  . SER A 1 48  ? 8.967   29.547  34.515 1   45.98  ? 30  SER H CA  1 
ATOM   193   C  C   . SER A 1 48  ? 9.165   28.059  34.849 1   47.35  ? 30  SER H C   1 
ATOM   194   O  O   . SER A 1 48  ? 10.334  27.618  34.867 1   48.1   ? 30  SER H O   1 
ATOM   195   C  CB  . SER A 1 48  ? 9.317   30.432  35.687 1   44.87  ? 30  SER H CB  1 
ATOM   196   O  OG  . SER A 1 48  ? 8.564   30.082  36.834 1   45.77  ? 30  SER H OG  1 
ATOM   197   N  N   . SER A 1 49  ? 8.084   27.317  35.112 1   48.48  ? 31  SER H N   1 
ATOM   198   C  CA  . SER A 1 49  ? 8.1     25.847  35.341 1   48.99  ? 31  SER H CA  1 
ATOM   199   C  C   . SER A 1 49  ? 8.501   25.105  34.059 1   49.39  ? 31  SER H C   1 
ATOM   200   O  O   . SER A 1 49  ? 9.215   24.092  34.173 1   51.22  ? 31  SER H O   1 
ATOM   201   C  CB  . SER A 1 49  ? 6.769   25.352  35.855 1   49.43  ? 31  SER H CB  1 
ATOM   202   O  OG  . SER A 1 49  ? 5.813   25.283  34.806 1   50.29  ? 31  SER H OG  1 
ATOM   203   N  N   . ASN A 1 50  ? 8.081   25.596  32.887 1   47.57  ? 32  ASN H N   1 
ATOM   204   C  CA  . ASN A 1 50  ? 8.182   24.866  31.591 1   47.42  ? 32  ASN H CA  1 
ATOM   205   C  C   . ASN A 1 50  ? 9.585   24.982  30.967 1   46.21  ? 32  ASN H C   1 
ATOM   206   O  O   . ASN A 1 50  ? 9.726   24.58   29.786 1   47.52  ? 32  ASN H O   1 
ATOM   207   C  CB  . ASN A 1 50  ? 7.127   25.364  30.596 1   49.02  ? 32  ASN H CB  1 
ATOM   208   C  CG  . ASN A 1 50  ? 5.703   25.087  31.028 1   49.01  ? 32  ASN H CG  1 
ATOM   209   O  OD1 . ASN A 1 50  ? 5.446   24.737  32.181 1   49.37  ? 32  ASN H OD1 1 
ATOM   210   N  ND2 . ASN A 1 50  ? 4.77    25.243  30.102 1   48.82  ? 32  ASN H ND2 1 
ATOM   211   N  N   . TYR A 1 51  ? 10.584  25.492  31.7   1   44.09  ? 33  TYR H N   1 
ATOM   212   C  CA  . TYR A 1 51  ? 11.941  25.809  31.181 1   43.91  ? 33  TYR H CA  1 
ATOM   213   C  C   . TYR A 1 51  ? 13.002  25.591  32.263 1   41.69  ? 33  TYR H C   1 
ATOM   214   O  O   . TYR A 1 51  ? 12.682  25.595  33.468 1   41.04  ? 33  TYR H O   1 
ATOM   215   C  CB  . TYR A 1 51  ? 12.007  27.26   30.691 1   45.31  ? 33  TYR H CB  1 
ATOM   216   C  CG  . TYR A 1 51  ? 11.083  27.563  29.541 1   47.18  ? 33  TYR H CG  1 
ATOM   217   C  CD1 . TYR A 1 51  ? 11.442  27.257  28.238 1   48.26  ? 33  TYR H CD1 1 
ATOM   218   C  CD2 . TYR A 1 51  ? 9.832   28.121  29.755 1   48.14  ? 33  TYR H CD2 1 
ATOM   219   C  CE1 . TYR A 1 51  ? 10.59   27.514  27.175 1   49.76  ? 33  TYR H CE1 1 
ATOM   220   C  CE2 . TYR A 1 51  ? 8.964   28.38   28.704 1   49.46  ? 33  TYR H CE2 1 
ATOM   221   C  CZ  . TYR A 1 51  ? 9.346   28.08   27.407 1   50.78  ? 33  TYR H CZ  1 
ATOM   222   O  OH  . TYR A 1 51  ? 8.505   28.337  26.361 1   53.7   ? 33  TYR H OH  1 
ATOM   223   N  N   . LEU A 1 52  ? 14.244  25.415  31.816 1   39.58  ? 34  LEU H N   1 
ATOM   224   C  CA  . LEU A 1 52  ? 15.459  25.518  32.66  1   40.92  ? 34  LEU H CA  1 
ATOM   225   C  C   . LEU A 1 52  ? 15.642  26.996  33.04  1   41.34  ? 34  LEU H C   1 
ATOM   226   O  O   . LEU A 1 52  ? 15.654  27.855  32.131 1   40.16  ? 34  LEU H O   1 
ATOM   227   C  CB  . LEU A 1 52  ? 16.652  24.947  31.886 1   41.7   ? 34  LEU H CB  1 
ATOM   228   C  CG  . LEU A 1 52  ? 18.013  25      32.579 1   44     ? 34  LEU H CG  1 
ATOM   229   C  CD1 . LEU A 1 52  ? 17.989  24.307  33.93  1   45.78  ? 34  LEU H CD1 1 
ATOM   230   C  CD2 . LEU A 1 52  ? 19.078  24.361  31.703 1   44.63  ? 34  LEU H CD2 1 
ATOM   231   N  N   . MET A 1 53  ? 15.697  27.278  34.344 1   41.11  ? 35  MET H N   1 
ATOM   232   C  CA  . MET A 1 53  ? 15.787  28.64   34.93  1   39.73  ? 35  MET H CA  1 
ATOM   233   C  C   . MET A 1 53  ? 17.052  28.696  35.784 1   38.88  ? 35  MET H C   1 
ATOM   234   O  O   . MET A 1 53  ? 17.321  27.707  36.484 1   38.86  ? 35  MET H O   1 
ATOM   235   C  CB  . MET A 1 53  ? 14.572  28.95   35.813 1   40.01  ? 35  MET H CB  1 
ATOM   236   C  CG  . MET A 1 53  ? 13.244  28.975  35.066 1   40.77  ? 35  MET H CG  1 
ATOM   237   S  SD  . MET A 1 53  ? 13.092  30.244  33.776 1   42.25  ? 35  MET H SD  1 
ATOM   238   C  CE  . MET A 1 53  ? 13.559  31.729  34.668 1   42.65  ? 35  MET H CE  1 
ATOM   239   N  N   . SER A 1 54  ? 17.79   29.806  35.718 1   37.98  ? 36  SER H N   1 
ATOM   240   C  CA  . SER A 1 54  ? 19.113  29.971  36.371 1   38.72  ? 36  SER H CA  1 
ATOM   241   C  C   . SER A 1 54  ? 19.197  31.316  37.102 1   38.44  ? 36  SER H C   1 
ATOM   242   O  O   . SER A 1 54  ? 18.444  32.246  36.757 1   36.1   ? 36  SER H O   1 
ATOM   243   C  CB  . SER A 1 54  ? 20.23   29.835  35.369 1   39.36  ? 36  SER H CB  1 
ATOM   244   O  OG  . SER A 1 54  ? 20.093  28.643  34.609 1   40.36  ? 36  SER H OG  1 
ATOM   245   N  N   . TRP A 1 55  ? 20.081  31.373  38.097 1   37.3   ? 37  TRP H N   1 
ATOM   246   C  CA  . TRP A 1 55  ? 20.624  32.61   38.698 1   37.69  ? 37  TRP H CA  1 
ATOM   247   C  C   . TRP A 1 55  ? 22.064  32.772  38.206 1   37.44  ? 37  TRP H C   1 
ATOM   248   O  O   . TRP A 1 55  ? 22.802  31.784  38.228 1   38.81  ? 37  TRP H O   1 
ATOM   249   C  CB  . TRP A 1 55  ? 20.515  32.555  40.227 1   37.81  ? 37  TRP H CB  1 
ATOM   250   C  CG  . TRP A 1 55  ? 19.119  32.78   40.721 1   37.36  ? 37  TRP H CG  1 
ATOM   251   C  CD1 . TRP A 1 55  ? 18.18   31.829  40.989 1   37.2   ? 37  TRP H CD1 1 
ATOM   252   C  CD2 . TRP A 1 55  ? 18.484  34.048  40.97  1   38.2   ? 37  TRP H CD2 1 
ATOM   253   N  NE1 . TRP A 1 55  ? 17.017  32.411  41.411 1   38.38  ? 37  TRP H NE1 1 
ATOM   254   C  CE2 . TRP A 1 55  ? 17.17   33.772  41.406 1   38.34  ? 37  TRP H CE2 1 
ATOM   255   C  CE3 . TRP A 1 55  ? 18.897  35.384  40.878 1   37.67  ? 37  TRP H CE3 1 
ATOM   256   C  CZ2 . TRP A 1 55  ? 16.272  34.783  41.749 1   37.94  ? 37  TRP H CZ2 1 
ATOM   257   C  CZ3 . TRP A 1 55  ? 18.011  36.381  41.219 1   37.28  ? 37  TRP H CZ3 1 
ATOM   258   C  CH2 . TRP A 1 55  ? 16.716  36.082  41.644 1   38.15  ? 37  TRP H CH2 1 
ATOM   259   N  N   . VAL A 1 56  ? 22.416  33.96   37.72  1   39.1   ? 38  VAL H N   1 
ATOM   260   C  CA  . VAL A 1 56  ? 23.787  34.312  37.245 1   39.35  ? 38  VAL H CA  1 
ATOM   261   C  C   . VAL A 1 56  ? 24.167  35.62   37.934 1   38.94  ? 38  VAL H C   1 
ATOM   262   O  O   . VAL A 1 56  ? 23.369  36.565  37.858 1   41.98  ? 38  VAL H O   1 
ATOM   263   C  CB  . VAL A 1 56  ? 23.845  34.427  35.708 1   40.25  ? 38  VAL H CB  1 
ATOM   264   C  CG1 . VAL A 1 56  ? 25.222  34.854  35.213 1   40.52  ? 38  VAL H CG1 1 
ATOM   265   C  CG2 . VAL A 1 56  ? 23.424  33.13   35.031 1   40.32  ? 38  VAL H CG2 1 
ATOM   266   N  N   . ARG A 1 57  ? 25.323  35.655  38.597 1   39.24  ? 39  ARG H N   1 
ATOM   267   C  CA  . ARG A 1 57  ? 25.763  36.807  39.421 1   39.88  ? 39  ARG H CA  1 
ATOM   268   C  C   . ARG A 1 57  ? 27.039  37.398  38.821 1   40.53  ? 39  ARG H C   1 
ATOM   269   O  O   . ARG A 1 57  ? 27.806  36.646  38.197 1   41.32  ? 39  ARG H O   1 
ATOM   270   C  CB  . ARG A 1 57  ? 25.953  36.393  40.884 1   41.54  ? 39  ARG H CB  1 
ATOM   271   C  CG  . ARG A 1 57  ? 27.288  35.739  41.209 1   42.35  ? 39  ARG H CG  1 
ATOM   272   C  CD  . ARG A 1 57  ? 27.395  35.45   42.691 1   43.74  ? 39  ARG H CD  1 
ATOM   273   N  NE  . ARG A 1 57  ? 28.564  34.639  43.009 1   45.55  ? 39  ARG H NE  1 
ATOM   274   C  CZ  . ARG A 1 57  ? 28.851  34.153  44.214 1   46.34  ? 39  ARG H CZ  1 
ATOM   275   N  NH1 . ARG A 1 57  ? 28.06   34.389  45.251 1   46.28  ? 39  ARG H NH1 1 
ATOM   276   N  NH2 . ARG A 1 57  ? 29.94   33.421  44.377 1   47.31  ? 39  ARG H NH2 1 
ATOM   277   N  N   . GLN A 1 58  ? 27.255  38.693  39.047 1   40.22  ? 40  GLN H N   1 
ATOM   278   C  CA  . GLN A 1 58  ? 28.407  39.461  38.514 1   41.07  ? 40  GLN H CA  1 
ATOM   279   C  C   . GLN A 1 58  ? 28.823  40.494  39.563 1   41.55  ? 40  GLN H C   1 
ATOM   280   O  O   . GLN A 1 58  ? 28.09   41.491  39.732 1   40.26  ? 40  GLN H O   1 
ATOM   281   C  CB  . GLN A 1 58  ? 28.014  40.101  37.181 1   41.42  ? 40  GLN H CB  1 
ATOM   282   C  CG  . GLN A 1 58  ? 29.105  40.974  36.577 1   41.26  ? 40  GLN H CG  1 
ATOM   283   C  CD  . GLN A 1 58  ? 28.768  41.422  35.177 1   41.93  ? 40  GLN H CD  1 
ATOM   284   O  OE1 . GLN A 1 58  ? 27.619  41.72   34.858 1   41.79  ? 40  GLN H OE1 1 
ATOM   285   N  NE2 . GLN A 1 58  ? 29.778  41.474  34.322 1   43.81  ? 40  GLN H NE2 1 
ATOM   286   N  N   . ALA A 1 59  ? 29.932  40.234  40.262 1   44.16  ? 41  ALA H N   1 
ATOM   287   C  CA  . ALA A 1 59  ? 30.536  41.142  41.265 1   47.16  ? 41  ALA H CA  1 
ATOM   288   C  C   . ALA A 1 59  ? 30.972  42.422  40.56  1   49.48  ? 41  ALA H C   1 
ATOM   289   O  O   . ALA A 1 59  ? 31.425  42.359  39.418 1   48.87  ? 41  ALA H O   1 
ATOM   290   C  CB  . ALA A 1 59  ? 31.697  40.469  41.957 1   48.43  ? 41  ALA H CB  1 
ATOM   291   N  N   . PRO A 1 60  ? 30.844  43.611  41.197 1   52.91  ? 42  PRO H N   1 
ATOM   292   C  CA  . PRO A 1 60  ? 31.1    44.88   40.51  1   54.39  ? 42  PRO H CA  1 
ATOM   293   C  C   . PRO A 1 60  ? 32.532  44.916  39.952 1   53.23  ? 42  PRO H C   1 
ATOM   294   O  O   . PRO A 1 60  ? 33.444  44.632  40.706 1   52.33  ? 42  PRO H O   1 
ATOM   295   C  CB  . PRO A 1 60  ? 30.856  45.955  41.585 1   55.32  ? 42  PRO H CB  1 
ATOM   296   C  CG  . PRO A 1 60  ? 30.969  45.211  42.904 1   56.11  ? 42  PRO H CG  1 
ATOM   297   C  CD  . PRO A 1 60  ? 30.484  43.806  42.61  1   54.42  ? 42  PRO H CD  1 
ATOM   298   N  N   . GLY A 1 61  ? 32.672  45.172  38.643 1   51.7   ? 43  GLY H N   1 
ATOM   299   C  CA  . GLY A 1 61  ? 33.963  45.221  37.928 1   50.61  ? 43  GLY H CA  1 
ATOM   300   C  C   . GLY A 1 61  ? 34.362  43.877  37.334 1   51.6   ? 43  GLY H C   1 
ATOM   301   O  O   . GLY A 1 61  ? 34.957  43.889  36.239 1   53.15  ? 43  GLY H O   1 
ATOM   302   N  N   . LYS A 1 62  ? 34.054  42.763  38.013 1   51.71  ? 44  LYS H N   1 
ATOM   303   C  CA  . LYS A 1 62  ? 34.527  41.388  37.672 1   51.26  ? 44  LYS H CA  1 
ATOM   304   C  C   . LYS A 1 62  ? 33.548  40.735  36.678 1   47.37  ? 44  LYS H C   1 
ATOM   305   O  O   . LYS A 1 62  ? 32.708  41.462  36.117 1   45.59  ? 44  LYS H O   1 
ATOM   306   C  CB  . LYS A 1 62  ? 34.73   40.588  38.965 1   54.1   ? 44  LYS H CB  1 
ATOM   307   C  CG  . LYS A 1 62  ? 35.595  41.272  40.02  1   58.75  ? 44  LYS H CG  1 
ATOM   308   C  CD  . LYS A 1 62  ? 36.093  40.334  41.116 1   64.05  ? 44  LYS H CD  1 
ATOM   309   C  CE  . LYS A 1 62  ? 36.403  41.032  42.427 1   65.06  ? 44  LYS H CE  1 
ATOM   310   N  NZ  . LYS A 1 62  ? 36.852  40.068  43.462 0   64.39  ? 44  LYS H NZ  1 
ATOM   311   N  N   . GLY A 1 63  ? 33.666  39.421  36.443 1   44.8   ? 45  GLY H N   1 
ATOM   312   C  CA  . GLY A 1 63  ? 32.99   38.707  35.338 1   44.32  ? 45  GLY H CA  1 
ATOM   313   C  C   . GLY A 1 63  ? 31.682  38.04   35.746 1   43.54  ? 45  GLY H C   1 
ATOM   314   O  O   . GLY A 1 63  ? 31.363  38.017  36.957 1   43.96  ? 45  GLY H O   1 
ATOM   315   N  N   . LEU A 1 64  ? 30.954  37.507  34.758 1   41.22  ? 46  LEU H N   1 
ATOM   316   C  CA  . LEU A 1 64  ? 29.723  36.693  34.952 1   40.8   ? 46  LEU H CA  1 
ATOM   317   C  C   . LEU A 1 64  ? 30.109  35.373  35.626 1   41.43  ? 46  LEU H C   1 
ATOM   318   O  O   . LEU A 1 64  ? 31.085  34.743  35.17  1   39.58  ? 46  LEU H O   1 
ATOM   319   C  CB  . LEU A 1 64  ? 29.051  36.395  33.607 1   38.83  ? 46  LEU H CB  1 
ATOM   320   C  CG  . LEU A 1 64  ? 28.565  37.593  32.801 1   36.95  ? 46  LEU H CG  1 
ATOM   321   C  CD1 . LEU A 1 64  ? 28.024  37.132  31.46  1   35.97  ? 46  LEU H CD1 1 
ATOM   322   C  CD2 . LEU A 1 64  ? 27.509  38.377  33.56  1   37.25  ? 46  LEU H CD2 1 
ATOM   323   N  N   . GLU A 1 65  ? 29.367  34.987  36.666 1   41.73  ? 47  GLU H N   1 
ATOM   324   C  CA  . GLU A 1 65  ? 29.494  33.678  37.353 1   42.99  ? 47  GLU H CA  1 
ATOM   325   C  C   . GLU A 1 65  ? 28.102  33.065  37.466 1   41.86  ? 47  GLU H C   1 
ATOM   326   O  O   . GLU A 1 65  ? 27.261  33.634  38.178 1   42.56  ? 47  GLU H O   1 
ATOM   327   C  CB  . GLU A 1 65  ? 30.127  33.817  38.74  1   45.7   ? 47  GLU H CB  1 
ATOM   328   C  CG  . GLU A 1 65  ? 30.52   32.476  39.346 1   47.46  ? 47  GLU H CG  1 
ATOM   329   C  CD  . GLU A 1 65  ? 30.943  32.483  40.804 1   48.28  ? 47  GLU H CD  1 
ATOM   330   O  OE1 . GLU A 1 65  ? 30.913  33.564  41.432 1   48.2   ? 47  GLU H OE1 1 
ATOM   331   O  OE2 . GLU A 1 65  ? 31.295  31.394  41.308 1   50.44  ? 47  GLU H OE2 1 
ATOM   332   N  N   . TRP A 1 66  ? 27.883  31.952  36.769 1   42.75  ? 48  TRP H N   1 
ATOM   333   C  CA  . TRP A 1 66  ? 26.704  31.072  36.953 1   42.02  ? 48  TRP H CA  1 
ATOM   334   C  C   . TRP A 1 66  ? 26.687  30.585  38.406 1   42.08  ? 48  TRP H C   1 
ATOM   335   O  O   . TRP A 1 66  ? 27.759  30.192  38.901 1   43.06  ? 48  TRP H O   1 
ATOM   336   C  CB  . TRP A 1 66  ? 26.749  29.911  35.961 1   42.38  ? 48  TRP H CB  1 
ATOM   337   C  CG  . TRP A 1 66  ? 25.653  28.922  36.179 1   43.49  ? 48  TRP H CG  1 
ATOM   338   C  CD1 . TRP A 1 66  ? 24.371  29.009  35.728 1   43     ? 48  TRP H CD1 1 
ATOM   339   C  CD2 . TRP A 1 66  ? 25.732  27.709  36.948 1   44.21  ? 48  TRP H CD2 1 
ATOM   340   N  NE1 . TRP A 1 66  ? 23.649  27.93   36.152 1   42.94  ? 48  TRP H NE1 1 
ATOM   341   C  CE2 . TRP A 1 66  ? 24.454  27.115  36.904 1   43.29  ? 48  TRP H CE2 1 
ATOM   342   C  CE3 . TRP A 1 66  ? 26.753  27.071  37.662 1   45.13  ? 48  TRP H CE3 1 
ATOM   343   C  CZ2 . TRP A 1 66  ? 24.178  25.904  37.541 1   44.51  ? 48  TRP H CZ2 1 
ATOM   344   C  CZ3 . TRP A 1 66  ? 26.476  25.881  38.302 1   46.04  ? 48  TRP H CZ3 1 
ATOM   345   C  CH2 . TRP A 1 66  ? 25.205  25.304  38.236 1   44.35  ? 48  TRP H CH2 1 
ATOM   346   N  N   . VAL A 1 67  ? 25.515  30.623  39.047 1   42.82  ? 49  VAL H N   1 
ATOM   347   C  CA  . VAL A 1 67  ? 25.313  30.392  40.509 1   42.52  ? 49  VAL H CA  1 
ATOM   348   C  C   . VAL A 1 67  ? 24.528  29.087  40.685 1   42.08  ? 49  VAL H C   1 
ATOM   349   O  O   . VAL A 1 67  ? 25.093  28.128  41.225 1   42.87  ? 49  VAL H O   1 
ATOM   350   C  CB  . VAL A 1 67  ? 24.608  31.608  41.144 1   43.51  ? 49  VAL H CB  1 
ATOM   351   C  CG1 . VAL A 1 67  ? 23.992  31.324  42.508 1   45.24  ? 49  VAL H CG1 1 
ATOM   352   C  CG2 . VAL A 1 67  ? 25.557  32.787  41.243 1   45.14  ? 49  VAL H CG2 1 
ATOM   353   N  N   . SER A 1 68  ? 23.272  29.066  40.239 1   42.11  ? 50  SER H N   1 
ATOM   354   C  CA  . SER A 1 68  ? 22.325  27.937  40.41  1   41.95  ? 50  SER H CA  1 
ATOM   355   C  C   . SER A 1 68  ? 21.466  27.775  39.152 1   42.42  ? 50  SER H C   1 
ATOM   356   O  O   . SER A 1 68  ? 21.285  28.768  38.413 1   40.3   ? 50  SER H O   1 
ATOM   357   C  CB  . SER A 1 68  ? 21.469  28.125  41.638 1   40.83  ? 50  SER H CB  1 
ATOM   358   O  OG  . SER A 1 68  ? 22.222  28.412  42.779 0   40.09  ? 50  SER H OG  1 
ATOM   359   N  N   . SER A 1 69  ? 20.993  26.548  38.916 1   42.17  ? 51  SER H N   1 
ATOM   360   C  CA  . SER A 1 69  ? 19.963  26.188  37.909 1   42.14  ? 51  SER H CA  1 
ATOM   361   C  C   . SER A 1 69  ? 18.892  25.334  38.582 1   42.32  ? 51  SER H C   1 
ATOM   362   O  O   . SER A 1 69  ? 19.216  24.674  39.588 1   43.41  ? 51  SER H O   1 
ATOM   363   C  CB  . SER A 1 69  ? 20.544  25.452  36.739 1   41.69  ? 51  SER H CB  1 
ATOM   364   O  OG  . SER A 1 69  ? 21.198  26.336  35.847 1   41.47  ? 51  SER H OG  1 
ATOM   365   N  N   . ILE A 1 70  ? 17.673  25.369  38.04  1   41.61  ? 52  ILE H N   1 
ATOM   366   C  CA  . ILE A 1 70  ? 16.56   24.437  38.383 1   42.14  ? 52  ILE H CA  1 
ATOM   367   C  C   . ILE A 1 70  ? 15.951  23.961  37.057 1   41.95  ? 52  ILE H C   1 
ATOM   368   O  O   . ILE A 1 70  ? 15.513  24.818  36.262 1   41.43  ? 52  ILE H O   1 
ATOM   369   C  CB  . ILE A 1 70  ? 15.548  25.087  39.356 1   42.47  ? 52  ILE H CB  1 
ATOM   370   C  CG1 . ILE A 1 70  ? 14.461  24.097  39.794 1   44.55  ? 52  ILE H CG1 1 
ATOM   371   C  CG2 . ILE A 1 70  ? 14.955  26.371  38.794 1   41.41  ? 52  ILE H CG2 1 
ATOM   372   C  CD1 . ILE A 1 70  ? 13.656  24.539  41.001 1   44.78  ? 52  ILE H CD1 1 
ATOM   373   N  N   . TYR A 1 71  ? 15.992  22.648  36.803 1   41.52  ? 53  TYR H N   1 
ATOM   374   C  CA  . TYR A 1 71  ? 15.533  22.032  35.531 1   41.65  ? 53  TYR H CA  1 
ATOM   375   C  C   . TYR A 1 71  ? 14.005  22.077  35.486 1   41.99  ? 53  TYR H C   1 
ATOM   376   O  O   . TYR A 1 71  ? 13.364  22.377  36.523 1   42.67  ? 53  TYR H O   1 
ATOM   377   C  CB  . TYR A 1 71  ? 16.106  20.621  35.343 1   42.42  ? 53  TYR H CB  1 
ATOM   378   C  CG  . TYR A 1 71  ? 17.461  20.602  34.68  1   42.86  ? 53  TYR H CG  1 
ATOM   379   C  CD1 . TYR A 1 71  ? 17.585  20.619  33.298 1   43.21  ? 53  TYR H CD1 1 
ATOM   380   C  CD2 . TYR A 1 71  ? 18.622  20.607  35.435 1   43.13  ? 53  TYR H CD2 1 
ATOM   381   C  CE1 . TYR A 1 71  ? 18.828  20.622  32.683 1   43.24  ? 53  TYR H CE1 1 
ATOM   382   C  CE2 . TYR A 1 71  ? 19.872  20.618  34.837 1   44.29  ? 53  TYR H CE2 1 
ATOM   383   C  CZ  . TYR A 1 71  ? 19.977  20.625  33.456 1   45.61  ? 53  TYR H CZ  1 
ATOM   384   O  OH  . TYR A 1 71  ? 21.215  20.629  32.875 1   50.03  ? 53  TYR H OH  1 
ATOM   385   N  N   . HIS A 1 72  ? 13.458  21.768  34.308 1   40.3   ? 54  HIS H N   1 
ATOM   386   C  CA  . HIS A 1 72  ? 12.019  21.898  33.956 1   41.36  ? 54  HIS H CA  1 
ATOM   387   C  C   . HIS A 1 72  ? 11.156  21.187  34.999 1   43.99  ? 54  HIS H C   1 
ATOM   388   O  O   . HIS A 1 72  ? 11.552  20.089  35.432 1   46.76  ? 54  HIS H O   1 
ATOM   389   C  CB  . HIS A 1 72  ? 11.701  21.277  32.591 1   39.8   ? 54  HIS H CB  1 
ATOM   390   C  CG  . HIS A 1 72  ? 12.484  21.82   31.449 1   37.64  ? 54  HIS H CG  1 
ATOM   391   N  ND1 . HIS A 1 72  ? 13.859  21.894  31.468 1   36.23  ? 54  HIS H ND1 1 
ATOM   392   C  CD2 . HIS A 1 72  ? 12.087  22.268  30.241 1   37.13  ? 54  HIS H CD2 1 
ATOM   393   C  CE1 . HIS A 1 72  ? 14.283  22.396  30.333 1   37.17  ? 54  HIS H CE1 1 
ATOM   394   N  NE2 . HIS A 1 72  ? 13.211  22.637  29.56  1   38.59  ? 54  HIS H NE2 1 
ATOM   395   N  N   . TYR A 1 73  ? 10.043  21.812  35.394 1   47.95  ? 55  TYR H N   1 
ATOM   396   C  CA  . TYR A 1 73  ? 8.868   21.181  36.077 1   48.65  ? 55  TYR H CA  1 
ATOM   397   C  C   . TYR A 1 73  ? 9.17    20.799  37.531 1   48.64  ? 55  TYR H C   1 
ATOM   398   O  O   . TYR A 1 73  ? 8.316   21.058  38.392 1   52.76  ? 55  TYR H O   1 
ATOM   399   C  CB  . TYR A 1 73  ? 8.385   19.947  35.306 1   48.64  ? 55  TYR H CB  1 
ATOM   400   C  CG  . TYR A 1 73  ? 7.879   20.271  33.926 1   50.25  ? 55  TYR H CG  1 
ATOM   401   C  CD1 . TYR A 1 73  ? 6.758   21.069  33.759 1   52.05  ? 55  TYR H CD1 1 
ATOM   402   C  CD2 . TYR A 1 73  ? 8.529   19.817  32.787 1   51.32  ? 55  TYR H CD2 1 
ATOM   403   C  CE1 . TYR A 1 73  ? 6.285   21.401  32.501 1   54.09  ? 55  TYR H CE1 1 
ATOM   404   C  CE2 . TYR A 1 73  ? 8.071   20.141  31.519 1   52.65  ? 55  TYR H CE2 1 
ATOM   405   C  CZ  . TYR A 1 73  ? 6.945   20.937  31.377 1   54.43  ? 55  TYR H CZ  1 
ATOM   406   O  OH  . TYR A 1 73  ? 6.453   21.275  30.152 1   57.82  ? 55  TYR H OH  1 
ATOM   407   N  N   . GLY A 1 74  ? 10.323  20.184  37.791 1   49.75  ? 56  GLY H N   1 
ATOM   408   C  CA  . GLY A 1 74  ? 10.65   19.586  39.104 1   52.69  ? 56  GLY H CA  1 
ATOM   409   C  C   . GLY A 1 74  ? 11.486  20.495  39.989 1   53.89  ? 56  GLY H C   1 
ATOM   410   O  O   . GLY A 1 74  ? 11.479  21.717  39.751 1   57.8   ? 56  GLY H O   1 
ATOM   411   N  N   . HIS A 1 75  ? 12.142  19.909  41.002 1   54.77  ? 57  HIS H N   1 
ATOM   412   C  CA  . HIS A 1 75  ? 13.07   20.574  41.96  1   56     ? 57  HIS H CA  1 
ATOM   413   C  C   . HIS A 1 75  ? 14.491  20.006  41.813 1   53.48  ? 57  HIS H C   1 
ATOM   414   O  O   . HIS A 1 75  ? 15.229  19.985  42.817 1   49.99  ? 57  HIS H O   1 
ATOM   415   C  CB  . HIS A 1 75  ? 12.578  20.423  43.412 1   61.65  ? 57  HIS H CB  1 
ATOM   416   C  CG  . HIS A 1 75  ? 11.132  20.725  43.638 1   69.64  ? 57  HIS H CG  1 
ATOM   417   N  ND1 . HIS A 1 75  ? 10.409  21.584  42.828 1   75.34  ? 57  HIS H ND1 1 
ATOM   418   C  CD2 . HIS A 1 75  ? 10.281  20.31   44.603 1   72.74  ? 57  HIS H CD2 1 
ATOM   419   C  CE1 . HIS A 1 75  ? 9.169   21.665  43.27  1   75.88  ? 57  HIS H CE1 1 
ATOM   420   N  NE2 . HIS A 1 75  ? 9.066   20.894  44.362 1   76.39  ? 57  HIS H NE2 1 
ATOM   421   N  N   A ASN A 1 76  ? 14.862  19.553  40.607 0.5 54.69  ? 58  ASN H N   1 
ATOM   422   N  N   B ASN A 1 76  ? 14.864  19.582  40.601 0.5 53.8   ? 58  ASN H N   1 
ATOM   423   C  CA  A ASN A 1 76  ? 16.225  19.051  40.281 0.5 54.95  ? 58  ASN H CA  1 
ATOM   424   C  CA  B ASN A 1 76  ? 16.216  19.057  40.27  0.5 53.58  ? 58  ASN H CA  1 
ATOM   425   C  C   A ASN A 1 76  ? 17.128  20.268  40.055 0.5 54.98  ? 58  ASN H C   1 
ATOM   426   C  C   B ASN A 1 76  ? 17.141  20.258  40.045 0.5 54.23  ? 58  ASN H C   1 
ATOM   427   O  O   A ASN A 1 76  ? 17.059  20.86   38.956 0.5 56.57  ? 58  ASN H O   1 
ATOM   428   O  O   B ASN A 1 76  ? 17.104  20.832  38.935 0.5 55.98  ? 58  ASN H O   1 
ATOM   429   C  CB  A ASN A 1 76  ? 16.231  18.113  39.069 0.5 54.97  ? 58  ASN H CB  1 
ATOM   430   C  CB  B ASN A 1 76  ? 16.165  18.106  39.071 0.5 52.58  ? 58  ASN H CB  1 
ATOM   431   C  CG  A ASN A 1 76  ? 17.59   17.502  38.793 0.5 54.71  ? 58  ASN H CG  1 
ATOM   432   C  CG  B ASN A 1 76  ? 15.198  16.959  39.278 0.5 51.3   ? 58  ASN H CG  1 
ATOM   433   O  OD1 A ASN A 1 76  ? 18.381  17.282  39.709 0.5 53.8   ? 58  ASN H OD1 1 
ATOM   434   O  OD1 B ASN A 1 76  ? 15.277  16.248  40.278 0.5 49.47  ? 58  ASN H OD1 1 
ATOM   435   N  ND2 A ASN A 1 76  ? 17.87   17.216  37.531 0.5 54.66  ? 58  ASN H ND2 1 
ATOM   436   N  ND2 B ASN A 1 76  ? 14.276  16.776  38.344 0.5 50.16  ? 58  ASN H ND2 1 
ATOM   437   N  N   . ALA A 1 77  ? 17.917  20.629  41.071 1   52.6   ? 59  ALA H N   1 
ATOM   438   C  CA  . ALA A 1 77  ? 18.735  21.859  41.111 1   51.5   ? 59  ALA H CA  1 
ATOM   439   C  C   . ALA A 1 77  ? 20.22   21.51   41.032 1   52.14  ? 59  ALA H C   1 
ATOM   440   O  O   . ALA A 1 77  ? 20.612  20.419  41.484 1   51.99  ? 59  ALA H O   1 
ATOM   441   C  CB  . ALA A 1 77  ? 18.427  22.631  42.367 1   52.11  ? 59  ALA H CB  1 
ATOM   442   N  N   . TYR A 1 78  ? 21.007  22.432  40.476 1   53.69  ? 60  TYR H N   1 
ATOM   443   C  CA  . TYR A 1 78  ? 22.487  22.367  40.402 1   53.15  ? 60  TYR H CA  1 
ATOM   444   C  C   . TYR A 1 78  ? 23.056  23.715  40.849 1   50.62  ? 60  TYR H C   1 
ATOM   445   O  O   . TYR A 1 78  ? 22.385  24.744  40.65  1   49.32  ? 60  TYR H O   1 
ATOM   446   C  CB  . TYR A 1 78  ? 22.916  21.943  38.997 1   54.52  ? 60  TYR H CB  1 
ATOM   447   C  CG  . TYR A 1 78  ? 22.601  20.502  38.698 1   56.03  ? 60  TYR H CG  1 
ATOM   448   C  CD1 . TYR A 1 78  ? 23.492  19.493  39.032 1   59.03  ? 60  TYR H CD1 1 
ATOM   449   C  CD2 . TYR A 1 78  ? 21.396  20.14   38.117 1   57.41  ? 60  TYR H CD2 1 
ATOM   450   C  CE1 . TYR A 1 78  ? 23.206  18.161  38.772 1   60.96  ? 60  TYR H CE1 1 
ATOM   451   C  CE2 . TYR A 1 78  ? 21.093  18.814  37.851 1   60.04  ? 60  TYR H CE2 1 
ATOM   452   C  CZ  . TYR A 1 78  ? 22      17.821  38.179 1   61.45  ? 60  TYR H CZ  1 
ATOM   453   O  OH  . TYR A 1 78  ? 21.711  16.514  37.91  1   63.85  ? 60  TYR H OH  1 
ATOM   454   N  N   . TYR A 1 79  ? 24.239  23.682  41.47  1   48.14  ? 61  TYR H N   1 
ATOM   455   C  CA  . TYR A 1 79  ? 24.89   24.84   42.134 1   46.42  ? 61  TYR H CA  1 
ATOM   456   C  C   . TYR A 1 79  ? 26.379  24.88   41.773 1   46.71  ? 61  TYR H C   1 
ATOM   457   O  O   . TYR A 1 79  ? 27.015  23.812  41.699 1   46.27  ? 61  TYR H O   1 
ATOM   458   C  CB  . TYR A 1 79  ? 24.693  24.747  43.649 1   45.08  ? 61  TYR H CB  1 
ATOM   459   C  CG  . TYR A 1 79  ? 23.25   24.684  44.081 1   44.97  ? 61  TYR H CG  1 
ATOM   460   C  CD1 . TYR A 1 79  ? 22.556  23.482  44.094 1   45.86  ? 61  TYR H CD1 1 
ATOM   461   C  CD2 . TYR A 1 79  ? 22.569  25.826  44.472 1   43.27  ? 61  TYR H CD2 1 
ATOM   462   C  CE1 . TYR A 1 79  ? 21.225  23.417  44.481 1   46.83  ? 61  TYR H CE1 1 
ATOM   463   C  CE2 . TYR A 1 79  ? 21.24   25.778  44.867 1   43.6   ? 61  TYR H CE2 1 
ATOM   464   C  CZ  . TYR A 1 79  ? 20.563  24.57   44.87  1   44.93  ? 61  TYR H CZ  1 
ATOM   465   O  OH  . TYR A 1 79  ? 19.254  24.502  45.259 1   42.7   ? 61  TYR H OH  1 
ATOM   466   N  N   . ALA A 1 80  ? 26.911  26.084  41.546 1   47.24  ? 62  ALA H N   1 
ATOM   467   C  CA  . ALA A 1 80  ? 28.365  26.359  41.489 1   50.24  ? 62  ALA H CA  1 
ATOM   468   C  C   . ALA A 1 80  ? 28.984  25.985  42.841 1   54.01  ? 62  ALA H C   1 
ATOM   469   O  O   . ALA A 1 80  ? 28.349  26.271  43.876 1   55.69  ? 62  ALA H O   1 
ATOM   470   C  CB  . ALA A 1 80  ? 28.612  27.808  41.152 1   50.28  ? 62  ALA H CB  1 
ATOM   471   N  N   . ASP A 1 81  ? 30.179  25.382  42.825 1   57.9   ? 63  ASP H N   1 
ATOM   472   C  CA  . ASP A 1 81  ? 30.906  24.887  44.029 1   60.42  ? 63  ASP H CA  1 
ATOM   473   C  C   . ASP A 1 81  ? 31.224  26.054  44.976 1   59.3   ? 63  ASP H C   1 
ATOM   474   O  O   . ASP A 1 81  ? 31.256  25.809  46.199 1   61.76  ? 63  ASP H O   1 
ATOM   475   C  CB  . ASP A 1 81  ? 32.168  24.105  43.64  1   62.19  ? 63  ASP H CB  1 
ATOM   476   C  CG  . ASP A 1 81  ? 31.881  22.832  42.857 1   65.66  ? 63  ASP H CG  1 
ATOM   477   O  OD1 . ASP A 1 81  ? 30.979  22.073  43.275 1   67.23  ? 63  ASP H OD1 1 
ATOM   478   O  OD2 . ASP A 1 81  ? 32.548  22.613  41.822 1   68.14  ? 63  ASP H OD2 1 
ATOM   479   N  N   . SER A 1 82  ? 31.402  27.273  44.447 1   57.34  ? 64  SER H N   1 
ATOM   480   C  CA  . SER A 1 82  ? 31.587  28.534  45.222 1   57.43  ? 64  SER H CA  1 
ATOM   481   C  C   . SER A 1 82  ? 30.402  28.783  46.167 1   56.82  ? 64  SER H C   1 
ATOM   482   O  O   . SER A 1 82  ? 30.58   29.543  47.141 1   55.69  ? 64  SER H O   1 
ATOM   483   C  CB  . SER A 1 82  ? 31.79   29.725  44.305 1   56.96  ? 64  SER H CB  1 
ATOM   484   O  OG  . SER A 1 82  ? 30.605  30.026  43.578 1   54.17  ? 64  SER H OG  1 
ATOM   485   N  N   . VAL A 1 83  ? 29.245  28.18   45.871 1   56.25  ? 65  VAL H N   1 
ATOM   486   C  CA  . VAL A 1 83  ? 27.916  28.497  46.472 1   58.03  ? 65  VAL H CA  1 
ATOM   487   C  C   . VAL A 1 83  ? 27.254  27.238  47.074 1   57.74  ? 65  VAL H C   1 
ATOM   488   O  O   . VAL A 1 83  ? 26.264  27.413  47.814 1   57.51  ? 65  VAL H O   1 
ATOM   489   C  CB  . VAL A 1 83  ? 27.079  29.204  45.379 1   60.14  ? 65  VAL H CB  1 
ATOM   490   C  CG1 . VAL A 1 83  ? 25.635  28.746  45.285 1   60.27  ? 65  VAL H CG1 1 
ATOM   491   C  CG2 . VAL A 1 83  ? 27.162  30.716  45.519 1   58.59  ? 65  VAL H CG2 1 
ATOM   492   N  N   . LYS A 1 84  ? 27.787  26.032  46.822 1   60.76  ? 66  LYS H N   1 
ATOM   493   C  CA  . LYS A 1 84  ? 27.223  24.723  47.274 1   62.36  ? 66  LYS H CA  1 
ATOM   494   C  C   . LYS A 1 84  ? 27.043  24.722  48.8   1   62.51  ? 66  LYS H C   1 
ATOM   495   O  O   . LYS A 1 84  ? 27.959  25.197  49.508 1   63.12  ? 66  LYS H O   1 
ATOM   496   C  CB  . LYS A 1 84  ? 28.152  23.576  46.856 1   65.12  ? 66  LYS H CB  1 
ATOM   497   C  CG  . LYS A 1 84  ? 27.64   22.166  47.131 1   67     ? 66  LYS H CG  1 
ATOM   498   C  CD  . LYS A 1 84  ? 28.726  21.211  47.601 1   68.14  ? 66  LYS H CD  1 
ATOM   499   C  CE  . LYS A 1 84  ? 28.197  19.821  47.886 0   68.76  ? 66  LYS H CE  1 
ATOM   500   N  NZ  . LYS A 1 84  ? 29.269  18.915  48.363 0   68.76  ? 66  LYS H NZ  1 
ATOM   501   N  N   . GLY A 1 85  ? 25.895  24.233  49.286 1   60.98  ? 67  GLY H N   1 
ATOM   502   C  CA  . GLY A 1 85  ? 25.59   24.095  50.726 1   60.57  ? 67  GLY H CA  1 
ATOM   503   C  C   . GLY A 1 85  ? 24.98   25.35   51.341 1   60.64  ? 67  GLY H C   1 
ATOM   504   O  O   . GLY A 1 85  ? 24.27   25.208  52.356 1   60.53  ? 67  GLY H O   1 
ATOM   505   N  N   . ARG A 1 86  ? 25.229  26.532  50.761 1   58.8   ? 68  ARG H N   1 
ATOM   506   C  CA  . ARG A 1 86  ? 24.829  27.85   51.323 1   55.21  ? 68  ARG H CA  1 
ATOM   507   C  C   . ARG A 1 86  ? 23.554  28.361  50.644 1   54.1   ? 68  ARG H C   1 
ATOM   508   O  O   . ARG A 1 86  ? 22.67   28.848  51.382 1   57.81  ? 68  ARG H O   1 
ATOM   509   C  CB  . ARG A 1 86  ? 25.987  28.839  51.184 1   54.23  ? 68  ARG H CB  1 
ATOM   510   C  CG  . ARG A 1 86  ? 27.198  28.456  52.018 1   55.05  ? 68  ARG H CG  1 
ATOM   511   C  CD  . ARG A 1 86  ? 28.225  29.558  52.132 1   55.01  ? 68  ARG H CD  1 
ATOM   512   N  NE  . ARG A 1 86  ? 28.682  29.995  50.818 1   55.3   ? 68  ARG H NE  1 
ATOM   513   C  CZ  . ARG A 1 86  ? 28.561  31.222  50.302 1   55.6   ? 68  ARG H CZ  1 
ATOM   514   N  NH1 . ARG A 1 86  ? 27.992  32.212  50.979 1   55.65  ? 68  ARG H NH1 1 
ATOM   515   N  NH2 . ARG A 1 86  ? 29.035  31.453  49.087 1   54.48  ? 68  ARG H NH2 1 
ATOM   516   N  N   . PHE A 1 87  ? 23.459  28.27   49.309 1   50.48  ? 69  PHE H N   1 
ATOM   517   C  CA  . PHE A 1 87  ? 22.344  28.843  48.502 1   48.58  ? 69  PHE H CA  1 
ATOM   518   C  C   . PHE A 1 87  ? 21.336  27.746  48.143 1   45.39  ? 69  PHE H C   1 
ATOM   519   O  O   . PHE A 1 87  ? 21.751  26.586  48.029 1   46.82  ? 69  PHE H O   1 
ATOM   520   C  CB  . PHE A 1 87  ? 22.84   29.485  47.2   1   46.78  ? 69  PHE H CB  1 
ATOM   521   C  CG  . PHE A 1 87  ? 23.663  30.75   47.305 1   45.36  ? 69  PHE H CG  1 
ATOM   522   C  CD1 . PHE A 1 87  ? 24.234  31.179  48.499 1   44.2   ? 69  PHE H CD1 1 
ATOM   523   C  CD2 . PHE A 1 87  ? 23.891  31.514  46.167 1   45.39  ? 69  PHE H CD2 1 
ATOM   524   C  CE1 . PHE A 1 87  ? 24.984  32.349  48.552 1   45.8   ? 69  PHE H CE1 1 
ATOM   525   C  CE2 . PHE A 1 87  ? 24.645  32.68   46.221 1   44.73  ? 69  PHE H CE2 1 
ATOM   526   C  CZ  . PHE A 1 87  ? 25.195  33.095  47.414 1   44.38  ? 69  PHE H CZ  1 
ATOM   527   N  N   . THR A 1 88  ? 20.071  28.124  47.921 1   44.71  ? 70  THR H N   1 
ATOM   528   C  CA  . THR A 1 88  ? 18.955  27.217  47.528 1   45.61  ? 70  THR H CA  1 
ATOM   529   C  C   . THR A 1 88  ? 18.068  27.899  46.478 1   46.72  ? 70  THR H C   1 
ATOM   530   O  O   . THR A 1 88  ? 17.452  28.937  46.814 1   48.42  ? 70  THR H O   1 
ATOM   531   C  CB  . THR A 1 88  ? 18.106  26.785  48.733 1   44.58  ? 70  THR H CB  1 
ATOM   532   O  OG1 . THR A 1 88  ? 18.971  26.459  49.822 1   44.64  ? 70  THR H OG1 1 
ATOM   533   C  CG2 . THR A 1 88  ? 17.21   25.606  48.418 1   43.46  ? 70  THR H CG2 1 
ATOM   534   N  N   . ILE A 1 89  ? 17.994  27.318  45.271 1   46.27  ? 71  ILE H N   1 
ATOM   535   C  CA  . ILE A 1 89  ? 17.088  27.757  44.164 1   44.91  ? 71  ILE H CA  1 
ATOM   536   C  C   . ILE A 1 89  ? 15.739  27.047  44.339 1   44.31  ? 71  ILE H C   1 
ATOM   537   O  O   . ILE A 1 89  ? 15.726  25.823  44.542 1   45.34  ? 71  ILE H O   1 
ATOM   538   C  CB  . ILE A 1 89  ? 17.707  27.541  42.76  1   43.33  ? 71  ILE H CB  1 
ATOM   539   C  CG1 . ILE A 1 89  ? 16.872  28.23   41.674 1   43.83  ? 71  ILE H CG1 1 
ATOM   540   C  CG2 . ILE A 1 89  ? 17.928  26.069  42.434 1   42.82  ? 71  ILE H CG2 1 
ATOM   541   C  CD1 . ILE A 1 89  ? 17.543  28.317  40.318 1   44.14  ? 71  ILE H CD1 1 
ATOM   542   N  N   . SER A 1 90  ? 14.645  27.802  44.287 1   46.1   ? 72  SER H N   1 
ATOM   543   C  CA  . SER A 1 90  ? 13.251  27.295  44.411 1   47.35  ? 72  SER H CA  1 
ATOM   544   C  C   . SER A 1 90  ? 12.37   27.995  43.373 1   46.79  ? 72  SER H C   1 
ATOM   545   O  O   . SER A 1 90  ? 12.857  28.941  42.73  1   45.82  ? 72  SER H O   1 
ATOM   546   C  CB  . SER A 1 90  ? 12.728  27.452  45.823 1   45.63  ? 72  SER H CB  1 
ATOM   547   O  OG  . SER A 1 90  ? 13.292  28.587  46.462 1   45.24  ? 72  SER H OG  1 
ATOM   548   N  N   . ARG A 1 91  ? 11.135  27.52   43.203 1   49.09  ? 73  ARG H N   1 
ATOM   549   C  CA  . ARG A 1 91  ? 10.202  27.983  42.144 1   52.44  ? 73  ARG H CA  1 
ATOM   550   C  C   . ARG A 1 91  ? 8.756   27.715  42.588 1   54.24  ? 73  ARG H C   1 
ATOM   551   O  O   . ARG A 1 91  ? 8.355   26.54   42.58  1   59.65  ? 73  ARG H O   1 
ATOM   552   C  CB  . ARG A 1 91  ? 10.578  27.274  40.84  1   53.98  ? 73  ARG H CB  1 
ATOM   553   C  CG  . ARG A 1 91  ? 9.757   27.68   39.626 1   56.43  ? 73  ARG H CG  1 
ATOM   554   C  CD  . ARG A 1 91  ? 9.688   26.562  38.606 1   57.95  ? 73  ARG H CD  1 
ATOM   555   N  NE  . ARG A 1 91  ? 10.85   26.542  37.722 1   61.86  ? 73  ARG H NE  1 
ATOM   556   C  CZ  . ARG A 1 91  ? 11.437  25.451  37.213 1   62.52  ? 73  ARG H CZ  1 
ATOM   557   N  NH1 . ARG A 1 91  ? 11.011  24.231  37.515 1   63.75  ? 73  ARG H NH1 1 
ATOM   558   N  NH2 . ARG A 1 91  ? 12.472  25.589  36.398 1   59.83  ? 73  ARG H NH2 1 
ATOM   559   N  N   . ASP A 1 92  ? 8.021   28.77   42.963 1   54.49  ? 74  ASP H N   1 
ATOM   560   C  CA  . ASP A 1 92  ? 6.57    28.751  43.299 1   52.81  ? 74  ASP H CA  1 
ATOM   561   C  C   . ASP A 1 92  ? 5.772   28.987  42.01  1   52.62  ? 74  ASP H C   1 
ATOM   562   O  O   . ASP A 1 92  ? 5.674   30.15   41.578 1   54.22  ? 74  ASP H O   1 
ATOM   563   C  CB  . ASP A 1 92  ? 6.258   29.79   44.383 1   54.96  ? 74  ASP H CB  1 
ATOM   564   C  CG  . ASP A 1 92  ? 4.813   29.853  44.864 1   54.85  ? 74  ASP H CG  1 
ATOM   565   O  OD1 . ASP A 1 92  ? 3.93    29.276  44.198 1   52.41  ? 74  ASP H OD1 1 
ATOM   566   O  OD2 . ASP A 1 92  ? 4.581   30.504  45.905 1   55.02  ? 74  ASP H OD2 1 
ATOM   567   N  N   . ASN A 1 93  ? 5.197   27.922  41.444 1   54.51  ? 75  ASN H N   1 
ATOM   568   C  CA  . ASN A 1 93  ? 4.487   27.933  40.135 1   56.08  ? 75  ASN H CA  1 
ATOM   569   C  C   . ASN A 1 93  ? 3.198   28.764  40.207 1   53.49  ? 75  ASN H C   1 
ATOM   570   O  O   . ASN A 1 93  ? 2.825   29.32   39.16  1   52.85  ? 75  ASN H O   1 
ATOM   571   C  CB  . ASN A 1 93  ? 4.184   26.513  39.646 1   59.33  ? 75  ASN H CB  1 
ATOM   572   C  CG  . ASN A 1 93  ? 5.422   25.73   39.258 1   60.88  ? 75  ASN H CG  1 
ATOM   573   O  OD1 . ASN A 1 93  ? 6.538   26.241  39.316 1   64.89  ? 75  ASN H OD1 1 
ATOM   574   N  ND2 . ASN A 1 93  ? 5.238   24.487  38.849 1   64.12  ? 75  ASN H ND2 1 
ATOM   575   N  N   . SER A 1 94  ? 2.545   28.842  41.373 1   51.53  ? 76  SER H N   1 
ATOM   576   C  CA  . SER A 1 94  ? 1.274   29.588  41.587 1   52.54  ? 76  SER H CA  1 
ATOM   577   C  C   . SER A 1 94  ? 1.504   31.105  41.468 1   53.03  ? 76  SER H C   1 
ATOM   578   O  O   . SER A 1 94  ? 0.574   31.798  41.021 1   52.26  ? 76  SER H O   1 
ATOM   579   C  CB  . SER A 1 94  ? 0.633   29.224  42.908 1   52.89  ? 76  SER H CB  1 
ATOM   580   O  OG  . SER A 1 94  ? 1.375   29.735  44.007 1   53.56  ? 76  SER H OG  1 
ATOM   581   N  N   . LYS A 1 95  ? 2.686   31.597  41.861 1   52.93  ? 77  LYS H N   1 
ATOM   582   C  CA  . LYS A 1 95  ? 3.119   33.014  41.696 1   52.44  ? 77  LYS H CA  1 
ATOM   583   C  C   . LYS A 1 95  ? 3.944   33.183  40.408 1   50.55  ? 77  LYS H C   1 
ATOM   584   O  O   . LYS A 1 95  ? 4.139   34.34   39.992 1   46.97  ? 77  LYS H O   1 
ATOM   585   C  CB  . LYS A 1 95  ? 3.931   33.468  42.913 1   54.7   ? 77  LYS H CB  1 
ATOM   586   C  CG  . LYS A 1 95  ? 3.199   33.422  44.248 1   56.83  ? 77  LYS H CG  1 
ATOM   587   C  CD  . LYS A 1 95  ? 4.089   33.742  45.436 1   58.04  ? 77  LYS H CD  1 
ATOM   588   C  CE  . LYS A 1 95  ? 3.367   33.647  46.766 1   58.84  ? 77  LYS H CE  1 
ATOM   589   N  NZ  . LYS A 1 95  ? 2.48    34.813  47     1   57.91  ? 77  LYS H NZ  1 
ATOM   590   N  N   . ASN A 1 96  ? 4.419   32.084  39.805 1   50.41  ? 78  ASN H N   1 
ATOM   591   C  CA  . ASN A 1 96  ? 5.306   32.072  38.606 1   47.97  ? 78  ASN H CA  1 
ATOM   592   C  C   . ASN A 1 96  ? 6.566   32.885  38.916 1   45.61  ? 78  ASN H C   1 
ATOM   593   O  O   . ASN A 1 96  ? 6.97    33.694  38.066 1   45.72  ? 78  ASN H O   1 
ATOM   594   C  CB  . ASN A 1 96  ? 4.599   32.595  37.347 1   47.07  ? 78  ASN H CB  1 
ATOM   595   C  CG  . ASN A 1 96  ? 5.361   32.331  36.061 1   45.94  ? 78  ASN H CG  1 
ATOM   596   O  OD1 . ASN A 1 96  ? 6.206   31.443  36     1   48.62  ? 78  ASN H OD1 1 
ATOM   597   N  ND2 . ASN A 1 96  ? 5.065   33.088  35.018 1   44.74  ? 78  ASN H ND2 1 
ATOM   598   N  N   . THR A 1 97  ? 7.141   32.702  40.107 1   43     ? 79  THR H N   1 
ATOM   599   C  CA  . THR A 1 97  ? 8.374   33.409  40.534 1   44.4   ? 79  THR H CA  1 
ATOM   600   C  C   . THR A 1 97  ? 9.44    32.373  40.907 1   44.03  ? 79  THR H C   1 
ATOM   601   O  O   . THR A 1 97  ? 9.086   31.32   41.476 1   40.92  ? 79  THR H O   1 
ATOM   602   C  CB  . THR A 1 97  ? 8.114   34.449  41.638 1   45.71  ? 79  THR H CB  1 
ATOM   603   O  OG1 . THR A 1 97  ? 8.088   33.816  42.915 1   47.57  ? 79  THR H OG1 1 
ATOM   604   C  CG2 . THR A 1 97  ? 6.827   35.223  41.454 1   46.2   ? 79  THR H CG2 1 
ATOM   605   N  N   . LEU A 1 98  ? 10.69   32.676  40.552 1   44.2   ? 80  LEU H N   1 
ATOM   606   C  CA  . LEU A 1 98  ? 11.91   31.917  40.917 1   44.88  ? 80  LEU H CA  1 
ATOM   607   C  C   . LEU A 1 98  ? 12.513  32.581  42.154 1   44.33  ? 80  LEU H C   1 
ATOM   608   O  O   . LEU A 1 98  ? 12.382  33.809  42.277 1   46.96  ? 80  LEU H O   1 
ATOM   609   C  CB  . LEU A 1 98  ? 12.874  31.959  39.728 1   46.89  ? 80  LEU H CB  1 
ATOM   610   C  CG  . LEU A 1 98  ? 14.019  30.953  39.766 1   50.38  ? 80  LEU H CG  1 
ATOM   611   C  CD1 . LEU A 1 98  ? 13.536  29.578  39.343 1   49.88  ? 80  LEU H CD1 1 
ATOM   612   C  CD2 . LEU A 1 98  ? 15.169  31.404  38.876 1   53.37  ? 80  LEU H CD2 1 
ATOM   613   N  N   . TYR A 1 99  ? 13.136  31.8    43.037 1   44.74  ? 81  TYR H N   1 
ATOM   614   C  CA  . TYR A 1 99  ? 13.791  32.293  44.275 1   44.4   ? 81  TYR H CA  1 
ATOM   615   C  C   . TYR A 1 99  ? 15.227  31.78   44.356 1   43.25  ? 81  TYR H C   1 
ATOM   616   O  O   . TYR A 1 99  ? 15.519  30.702  43.817 1   44.39  ? 81  TYR H O   1 
ATOM   617   C  CB  . TYR A 1 99  ? 13.031  31.851  45.524 1   44.74  ? 81  TYR H CB  1 
ATOM   618   C  CG  . TYR A 1 99  ? 11.601  32.313  45.579 1   46.11  ? 81  TYR H CG  1 
ATOM   619   C  CD1 . TYR A 1 99  ? 10.591  31.549  45.021 1   46.68  ? 81  TYR H CD1 1 
ATOM   620   C  CD2 . TYR A 1 99  ? 11.258  33.517  46.172 1   47.4   ? 81  TYR H CD2 1 
ATOM   621   C  CE1 . TYR A 1 99  ? 9.27    31.959  45.069 1   48.48  ? 81  TYR H CE1 1 
ATOM   622   C  CE2 . TYR A 1 99  ? 9.942   33.947  46.217 1   47.61  ? 81  TYR H CE2 1 
ATOM   623   C  CZ  . TYR A 1 99  ? 8.942   33.16   45.673 1   47.78  ? 81  TYR H CZ  1 
ATOM   624   O  OH  . TYR A 1 99  ? 7.639   33.565  45.71  1   49.49  ? 81  TYR H OH  1 
ATOM   625   N  N   . LEU A 1 100 ? 16.08   32.556  45.023 1   43.18  ? 82  LEU H N   1 
ATOM   626   C  CA  . LEU A 1 100 ? 17.424  32.146  45.489 1   44.47  ? 82  LEU H CA  1 
ATOM   627   C  C   . LEU A 1 100 ? 17.518  32.495  46.974 1   46.6   ? 82  LEU H C   1 
ATOM   628   O  O   . LEU A 1 100 ? 17.589  33.698  47.297 1   46     ? 82  LEU H O   1 
ATOM   629   C  CB  . LEU A 1 100 ? 18.498  32.863  44.663 1   43.73  ? 82  LEU H CB  1 
ATOM   630   C  CG  . LEU A 1 100 ? 19.941  32.472  44.972 1   43.67  ? 82  LEU H CG  1 
ATOM   631   C  CD1 . LEU A 1 100 ? 20.209  31.029  44.577 1   45.15  ? 82  LEU H CD1 1 
ATOM   632   C  CD2 . LEU A 1 100 ? 20.914  33.4    44.266 1   44.77  ? 82  LEU H CD2 1 
ATOM   633   N  N   . GLN A 1 101 ? 17.456  31.477  47.833 1   49.19  ? 83  GLN H N   1 
ATOM   634   C  CA  . GLN A 1 101 ? 17.739  31.596  49.285 1   51.52  ? 83  GLN H CA  1 
ATOM   635   C  C   . GLN A 1 101 ? 19.261  31.592  49.438 1   51.7   ? 83  GLN H C   1 
ATOM   636   O  O   . GLN A 1 101 ? 19.888  30.671  48.897 1   51.36  ? 83  GLN H O   1 
ATOM   637   C  CB  . GLN A 1 101 ? 17.064  30.454  50.049 1   55.31  ? 83  GLN H CB  1 
ATOM   638   C  CG  . GLN A 1 101 ? 17.264  30.5    51.558 1   57.11  ? 83  GLN H CG  1 
ATOM   639   C  CD  . GLN A 1 101 ? 16.615  31.714  52.175 1   58.81  ? 83  GLN H CD  1 
ATOM   640   O  OE1 . GLN A 1 101 ? 15.433  31.977  51.957 1   60.06  ? 83  GLN H OE1 1 
ATOM   641   N  NE2 . GLN A 1 101 ? 17.385  32.469  52.946 1   61.48  ? 83  GLN H NE2 1 
ATOM   642   N  N   . MET A 1 102 ? 19.825  32.602  50.104 1   54.18  ? 84  MET H N   1 
ATOM   643   C  CA  . MET A 1 102 ? 21.29   32.763  50.31  1   57.44  ? 84  MET H CA  1 
ATOM   644   C  C   . MET A 1 102 ? 21.562  32.836  51.817 1   57.72  ? 84  MET H C   1 
ATOM   645   O  O   . MET A 1 102 ? 21.025  33.759  52.448 1   61.2   ? 84  MET H O   1 
ATOM   646   C  CB  . MET A 1 102 ? 21.806  34.032  49.618 1   59     ? 84  MET H CB  1 
ATOM   647   C  CG  . MET A 1 102 ? 21.714  33.974  48.096 1   60.76  ? 84  MET H CG  1 
ATOM   648   S  SD  . MET A 1 102 ? 21.659  35.593  47.269 1   62.8   ? 84  MET H SD  1 
ATOM   649   C  CE  . MET A 1 102 ? 23.199  36.328  47.805 1   64.71  ? 84  MET H CE  1 
ATOM   650   N  N   . ASN A 1 103 ? 22.329  31.878  52.36  1   56.37  ? 85  ASN H N   1 
ATOM   651   C  CA  . ASN A 1 103 ? 22.723  31.793  53.797 1   55.98  ? 85  ASN H CA  1 
ATOM   652   C  C   . ASN A 1 103 ? 24.246  31.904  53.926 1   57.77  ? 85  ASN H C   1 
ATOM   653   O  O   . ASN A 1 103 ? 24.946  31.762  52.902 1   58.1   ? 85  ASN H O   1 
ATOM   654   C  CB  . ASN A 1 103 ? 22.245  30.492  54.446 1   53.94  ? 85  ASN H CB  1 
ATOM   655   C  CG  . ASN A 1 103 ? 20.748  30.293  54.34  1   53.96  ? 85  ASN H CG  1 
ATOM   656   O  OD1 . ASN A 1 103 ? 19.975  31.228  54.546 1   53.4   ? 85  ASN H OD1 1 
ATOM   657   N  ND2 . ASN A 1 103 ? 20.323  29.082  54.017 1   55.67  ? 85  ASN H ND2 1 
ATOM   658   N  N   . SER A 1 104 ? 24.736  32.153  55.144 1   60.23  ? 86  SER H N   1 
ATOM   659   C  CA  . SER A 1 104 ? 26.182  32.227  55.484 1   62.14  ? 86  SER H CA  1 
ATOM   660   C  C   . SER A 1 104 ? 26.907  33.109  54.456 1   62.86  ? 86  SER H C   1 
ATOM   661   O  O   . SER A 1 104 ? 27.882  32.636  53.835 1   69.26  ? 86  SER H O   1 
ATOM   662   C  CB  . SER A 1 104 ? 26.775  30.838  55.558 1   61.81  ? 86  SER H CB  1 
ATOM   663   O  OG  . SER A 1 104 ? 26.069  30.033  56.489 1   61.82  ? 86  SER H OG  1 
ATOM   664   N  N   . LEU A 1 105 ? 26.422  34.338  54.26  1   60.75  ? 87  LEU H N   1 
ATOM   665   C  CA  . LEU A 1 105 ? 26.89   35.237  53.171 1   58.03  ? 87  LEU H CA  1 
ATOM   666   C  C   . LEU A 1 105 ? 28.236  35.86   53.546 1   56.02  ? 87  LEU H C   1 
ATOM   667   O  O   . LEU A 1 105 ? 28.442  36.16   54.727 1   56.48  ? 87  LEU H O   1 
ATOM   668   C  CB  . LEU A 1 105 ? 25.834  36.307  52.879 1   57.26  ? 87  LEU H CB  1 
ATOM   669   C  CG  . LEU A 1 105 ? 24.709  35.863  51.949 1   58.13  ? 87  LEU H CG  1 
ATOM   670   C  CD1 . LEU A 1 105 ? 23.63   36.928  51.856 1   58.48  ? 87  LEU H CD1 1 
ATOM   671   C  CD2 . LEU A 1 105 ? 25.25   35.536  50.564 1   60.04  ? 87  LEU H CD2 1 
ATOM   672   N  N   . ARG A 1 106 ? 29.1    36.034  52.545 1   57.91  ? 88  ARG H N   1 
ATOM   673   C  CA  . ARG A 1 106 ? 30.499  36.52   52.668 1   60.67  ? 88  ARG H CA  1 
ATOM   674   C  C   . ARG A 1 106 ? 30.662  37.778  51.805 1   59.87  ? 88  ARG H C   1 
ATOM   675   O  O   . ARG A 1 106 ? 29.81   38.003  50.924 1   58.73  ? 88  ARG H O   1 
ATOM   676   C  CB  . ARG A 1 106 ? 31.492  35.453  52.187 1   65.86  ? 88  ARG H CB  1 
ATOM   677   C  CG  . ARG A 1 106 ? 31.191  34.022  52.616 1   68.83  ? 88  ARG H CG  1 
ATOM   678   C  CD  . ARG A 1 106 ? 32.004  33.023  51.805 1   70.15  ? 88  ARG H CD  1 
ATOM   679   N  NE  . ARG A 1 106 ? 31.699  31.628  52.119 1   72.3   ? 88  ARG H NE  1 
ATOM   680   C  CZ  . ARG A 1 106 ? 32.137  30.567  51.434 1   73.22  ? 88  ARG H CZ  1 
ATOM   681   N  NH1 . ARG A 1 106 ? 32.911  30.716  50.369 1   75.21  ? 88  ARG H NH1 1 
ATOM   682   N  NH2 . ARG A 1 106 ? 31.789  29.347  51.814 1   71.56  ? 88  ARG H NH2 1 
ATOM   683   N  N   . ALA A 1 107 ? 31.739  38.538  52.024 1   60.03  ? 89  ALA H N   1 
ATOM   684   C  CA  . ALA A 1 107 ? 32.137  39.713  51.21  1   60.23  ? 89  ALA H CA  1 
ATOM   685   C  C   . ALA A 1 107 ? 32.142  39.358  49.714 1   61.45  ? 89  ALA H C   1 
ATOM   686   O  O   . ALA A 1 107 ? 31.613  40.16   48.924 1   62.78  ? 89  ALA H O   1 
ATOM   687   C  CB  . ALA A 1 107 ? 33.488  40.222  51.651 1   59.47  ? 89  ALA H CB  1 
ATOM   688   N  N   . GLU A 1 108 ? 32.675  38.186  49.344 1   61.91  ? 90  GLU H N   1 
ATOM   689   C  CA  . GLU A 1 108 ? 32.859  37.766  47.921 1   63.21  ? 90  GLU H CA  1 
ATOM   690   C  C   . GLU A 1 108 ? 31.534  37.298  47.289 1   60.11  ? 90  GLU H C   1 
ATOM   691   O  O   . GLU A 1 108 ? 31.568  36.933  46.097 1   59.49  ? 90  GLU H O   1 
ATOM   692   C  CB  . GLU A 1 108 ? 33.964  36.711  47.761 1   66.85  ? 90  GLU H CB  1 
ATOM   693   C  CG  . GLU A 1 108 ? 33.901  35.54   48.729 1   71.71  ? 90  GLU H CG  1 
ATOM   694   C  CD  . GLU A 1 108 ? 34.847  35.673  49.913 1   76.61  ? 90  GLU H CD  1 
ATOM   695   O  OE1 . GLU A 1 108 ? 35.656  34.743  50.132 1   80.54  ? 90  GLU H OE1 1 
ATOM   696   O  OE2 . GLU A 1 108 ? 34.783  36.715  50.603 1   75.43  ? 90  GLU H OE2 1 
ATOM   697   N  N   . ASP A 1 109 ? 30.407  37.329  48.015 1   55.8   ? 91  ASP H N   1 
ATOM   698   C  CA  . ASP A 1 109 ? 29.048  37.119  47.443 1   53.61  ? 91  ASP H CA  1 
ATOM   699   C  C   . ASP A 1 109 ? 28.42   38.455  47.011 1   50.09  ? 91  ASP H C   1 
ATOM   700   O  O   . ASP A 1 109 ? 27.387  38.413  46.314 1   47.92  ? 91  ASP H O   1 
ATOM   701   C  CB  . ASP A 1 109 ? 28.156  36.369  48.431 1   56.43  ? 91  ASP H CB  1 
ATOM   702   C  CG  . ASP A 1 109 ? 28.667  34.974  48.732 1   57.94  ? 91  ASP H CG  1 
ATOM   703   O  OD1 . ASP A 1 109 ? 29.009  34.259  47.769 1   57.15  ? 91  ASP H OD1 1 
ATOM   704   O  OD2 . ASP A 1 109 ? 28.731  34.615  49.925 1   61.04  ? 91  ASP H OD2 1 
ATOM   705   N  N   . THR A 1 110 ? 29.002  39.595  47.399 1   47.36  ? 92  THR H N   1 
ATOM   706   C  CA  . THR A 1 110 ? 28.609  40.937  46.9   1   47.75  ? 92  THR H CA  1 
ATOM   707   C  C   . THR A 1 110 ? 28.621  40.897  45.371 1   45.81  ? 92  THR H C   1 
ATOM   708   O  O   . THR A 1 110 ? 29.706  40.662  44.807 1   46.69  ? 92  THR H O   1 
ATOM   709   C  CB  . THR A 1 110 ? 29.54   42.036  47.428 1   50.46  ? 92  THR H CB  1 
ATOM   710   O  OG1 . THR A 1 110 ? 29.416  42.061  48.852 1   53.8   ? 92  THR H OG1 1 
ATOM   711   C  CG2 . THR A 1 110 ? 29.241  43.406  46.856 1   49.81  ? 92  THR H CG2 1 
ATOM   712   N  N   . ALA A 1 111 ? 27.463  41.099  44.737 1   44.56  ? 93  ALA H N   1 
ATOM   713   C  CA  . ALA A 1 111 ? 27.304  41.089  43.263 1   44.3   ? 93  ALA H CA  1 
ATOM   714   C  C   . ALA A 1 111 ? 25.89   41.502  42.853 1   42.7   ? 93  ALA H C   1 
ATOM   715   O  O   . ALA A 1 111 ? 24.973  41.46   43.698 1   42.17  ? 93  ALA H O   1 
ATOM   716   C  CB  . ALA A 1 111 ? 27.613  39.713  42.719 1   45.32  ? 93  ALA H CB  1 
ATOM   717   N  N   . VAL A 1 112 ? 25.737  41.865  41.577 1   41.95  ? 94  VAL H N   1 
ATOM   718   C  CA  . VAL A 1 112 ? 24.426  41.877  40.868 1   40.4   ? 94  VAL H CA  1 
ATOM   719   C  C   . VAL A 1 112 ? 24.056  40.415  40.617 1   40.28  ? 94  VAL H C   1 
ATOM   720   O  O   . VAL A 1 112 ? 24.926  39.672  40.124 1   38.47  ? 94  VAL H O   1 
ATOM   721   C  CB  . VAL A 1 112 ? 24.465  42.672  39.549 1   41.68  ? 94  VAL H CB  1 
ATOM   722   C  CG1 . VAL A 1 112 ? 23.142  42.589  38.798 1   41.79  ? 94  VAL H CG1 1 
ATOM   723   C  CG2 . VAL A 1 112 ? 24.859  44.125  39.771 1   42.09  ? 94  VAL H CG2 1 
ATOM   724   N  N   . TYR A 1 113 ? 22.827  40.038  40.973 1   38.54  ? 95  TYR H N   1 
ATOM   725   C  CA  . TYR A 1 113 ? 22.232  38.701  40.757 1   38.57  ? 95  TYR H CA  1 
ATOM   726   C  C   . TYR A 1 113 ? 21.114  38.843  39.725 1   39.11  ? 95  TYR H C   1 
ATOM   727   O  O   . TYR A 1 113 ? 20.116  39.543  40.018 1   42.19  ? 95  TYR H O   1 
ATOM   728   C  CB  . TYR A 1 113 ? 21.722  38.131  42.082 1   39.17  ? 95  TYR H CB  1 
ATOM   729   C  CG  . TYR A 1 113 ? 22.805  37.652  43.013 1   38.14  ? 95  TYR H CG  1 
ATOM   730   C  CD1 . TYR A 1 113 ? 23.548  38.548  43.763 1   38.38  ? 95  TYR H CD1 1 
ATOM   731   C  CD2 . TYR A 1 113 ? 23.09   36.301  43.147 1   38.46  ? 95  TYR H CD2 1 
ATOM   732   C  CE1 . TYR A 1 113 ? 24.541  38.118  44.629 1   37.89  ? 95  TYR H CE1 1 
ATOM   733   C  CE2 . TYR A 1 113 ? 24.083  35.853  44.005 1   36.71  ? 95  TYR H CE2 1 
ATOM   734   C  CZ  . TYR A 1 113 ? 24.812  36.765  44.745 1   36.37  ? 95  TYR H CZ  1 
ATOM   735   O  OH  . TYR A 1 113 ? 25.792  36.333  45.585 1   36.51  ? 95  TYR H OH  1 
ATOM   736   N  N   . TYR A 1 114 ? 21.293  38.226  38.554 1   37.93  ? 96  TYR H N   1 
ATOM   737   C  CA  . TYR A 1 114 ? 20.27   38.105  37.484 1   38.07  ? 96  TYR H CA  1 
ATOM   738   C  C   . TYR A 1 114 ? 19.622  36.722  37.569 1   39.86  ? 96  TYR H C   1 
ATOM   739   O  O   . TYR A 1 114 ? 20.362  35.756  37.821 1   40.19  ? 96  TYR H O   1 
ATOM   740   C  CB  . TYR A 1 114 ? 20.893  38.25   36.092 1   38.06  ? 96  TYR H CB  1 
ATOM   741   C  CG  . TYR A 1 114 ? 21.707  39.496  35.864 1   36.21  ? 96  TYR H CG  1 
ATOM   742   C  CD1 . TYR A 1 114 ? 21.116  40.666  35.412 1   35.83  ? 96  TYR H CD1 1 
ATOM   743   C  CD2 . TYR A 1 114 ? 23.076  39.501  36.077 1   36.05  ? 96  TYR H CD2 1 
ATOM   744   C  CE1 . TYR A 1 114 ? 21.861  41.814  35.194 1   35.79  ? 96  TYR H CE1 1 
ATOM   745   C  CE2 . TYR A 1 114 ? 23.835  40.641  35.868 1   36.3   ? 96  TYR H CE2 1 
ATOM   746   C  CZ  . TYR A 1 114 ? 23.225  41.799  35.421 1   36.09  ? 96  TYR H CZ  1 
ATOM   747   O  OH  . TYR A 1 114 ? 23.971  42.918  35.212 1   40.39  ? 96  TYR H OH  1 
ATOM   748   N  N   . CYS A 1 115 ? 18.304  36.632  37.373 1   42.2   ? 97  CYS H N   1 
ATOM   749   C  CA  . CYS A 1 115 ? 17.626  35.384  36.931 1   45.52  ? 97  CYS H CA  1 
ATOM   750   C  C   . CYS A 1 115 ? 17.618  35.38   35.399 1   42.6   ? 97  CYS H C   1 
ATOM   751   O  O   . CYS A 1 115 ? 17.73   36.467  34.797 1   40.91  ? 97  CYS H O   1 
ATOM   752   C  CB  . CYS A 1 115 ? 16.225  35.207  37.512 1   49     ? 97  CYS H CB  1 
ATOM   753   S  SG  . CYS A 1 115 ? 15.143  36.633  37.26  1   58.93  ? 97  CYS H SG  1 
ATOM   754   N  N   . ALA A 1 116 ? 17.547  34.195  34.794 1   40.42  ? 98  ALA H N   1 
ATOM   755   C  CA  . ALA A 1 116 ? 17.636  34.026  33.33  1   40.55  ? 98  ALA H CA  1 
ATOM   756   C  C   . ALA A 1 116 ? 16.85   32.794  32.895 1   40.05  ? 98  ALA H C   1 
ATOM   757   O  O   . ALA A 1 116 ? 16.941  31.759  33.58  1   39.86  ? 98  ALA H O   1 
ATOM   758   C  CB  . ALA A 1 116 ? 19.079  33.927  32.91  1   41.09  ? 98  ALA H CB  1 
ATOM   759   N  N   . LYS A 1 117 ? 16.1    32.931  31.803 1   41.68  ? 99  LYS H N   1 
ATOM   760   C  CA  . LYS A 1 117 ? 15.405  31.816  31.116 1   43.27  ? 99  LYS H CA  1 
ATOM   761   C  C   . LYS A 1 117 ? 16.399  31.187  30.136 1   42.84  ? 99  LYS H C   1 
ATOM   762   O  O   . LYS A 1 117 ? 16.907  31.911  29.249 1   40.67  ? 99  LYS H O   1 
ATOM   763   C  CB  . LYS A 1 117 ? 14.148  32.333  30.413 1   46.73  ? 99  LYS H CB  1 
ATOM   764   C  CG  . LYS A 1 117 ? 13.313  31.28   29.698 1   50.33  ? 99  LYS H CG  1 
ATOM   765   C  CD  . LYS A 1 117 ? 12.279  31.869  28.767 1   52.97  ? 99  LYS H CD  1 
ATOM   766   C  CE  . LYS A 1 117 ? 11.841  30.899  27.694 1   55.14  ? 99  LYS H CE  1 
ATOM   767   N  NZ  . LYS A 1 117 ? 10.577  31.336  27.054 1   58.75  ? 99  LYS H NZ  1 
ATOM   768   N  N   . VAL A 1 118 ? 16.671  29.893  30.302 1   41.47  ? 100 VAL H N   1 
ATOM   769   C  CA  . VAL A 1 118 ? 17.481  29.091  29.342 1   40.81  ? 100 VAL H CA  1 
ATOM   770   C  C   . VAL A 1 118 ? 16.554  28.658  28.2   1   41.44  ? 100 VAL H C   1 
ATOM   771   O  O   . VAL A 1 118 ? 15.419  28.249  28.495 1   42.11  ? 100 VAL H O   1 
ATOM   772   C  CB  . VAL A 1 118 ? 18.144  27.886  30.03  1   40.06  ? 100 VAL H CB  1 
ATOM   773   C  CG1 . VAL A 1 118 ? 19.001  27.099  29.056 1   41.17  ? 100 VAL H CG1 1 
ATOM   774   C  CG2 . VAL A 1 118 ? 18.963  28.297  31.247 1   39.63  ? 100 VAL H CG2 1 
ATOM   775   N  N   . ASP A 1 119 ? 17.018  28.759  26.952 1   43.46  ? 101 ASP H N   1 
ATOM   776   C  CA  . ASP A 1 119 ? 16.276  28.331  25.736 1   45.94  ? 101 ASP H CA  1 
ATOM   777   C  C   . ASP A 1 119 ? 16.702  26.893  25.384 1   46.4   ? 101 ASP H C   1 
ATOM   778   O  O   . ASP A 1 119 ? 16.71   26.044  26.299 1   45.92  ? 101 ASP H O   1 
ATOM   779   C  CB  . ASP A 1 119 ? 16.46   29.353  24.608 1   49.68  ? 101 ASP H CB  1 
ATOM   780   C  CG  . ASP A 1 119 ? 15.95   30.751  24.92  1   52.15  ? 101 ASP H CG  1 
ATOM   781   O  OD1 . ASP A 1 119 ? 15.286  30.929  25.965 1   57.78  ? 101 ASP H OD1 1 
ATOM   782   O  OD2 . ASP A 1 119 ? 16.209  31.652  24.103 1   52.66  ? 101 ASP H OD2 1 
ATOM   783   N  N   . SER A 1 120 ? 17.056  26.621  24.123 1   46.69  ? 102 SER H N   1 
ATOM   784   C  CA  . SER A 1 120 ? 17.118  25.257  23.538 1   46.6   ? 102 SER H CA  1 
ATOM   785   C  C   . SER A 1 120 ? 18.477  24.585  23.781 1   46.98  ? 102 SER H C   1 
ATOM   786   O  O   . SER A 1 120 ? 18.523  23.341  23.68  1   48.96  ? 102 SER H O   1 
ATOM   787   C  CB  . SER A 1 120 ? 16.799  25.296  22.061 1   48.58  ? 102 SER H CB  1 
ATOM   788   O  OG  . SER A 1 120 ? 17.767  26.054  21.341 1   51.28  ? 102 SER H OG  1 
ATOM   789   N  N   . ALA A 1 121 ? 19.527  25.354  24.105 1   45.29  ? 103 ALA H N   1 
ATOM   790   C  CA  . ALA A 1 121 ? 20.944  24.931  23.987 1   44.06  ? 103 ALA H CA  1 
ATOM   791   C  C   . ALA A 1 121 ? 21.8    25.448  25.153 1   43.29  ? 103 ALA H C   1 
ATOM   792   O  O   . ALA A 1 121 ? 22.956  25.844  24.906 1   44.8   ? 103 ALA H O   1 
ATOM   793   C  CB  . ALA A 1 121 ? 21.47   25.415  22.66  1   43.72  ? 103 ALA H CB  1 
ATOM   794   N  N   . TYR A 1 122 ? 21.282  25.41   26.383 1   43.1   ? 104 TYR H N   1 
ATOM   795   C  CA  . TYR A 1 122 ? 21.976  25.91   27.603 1   42.73  ? 104 TYR H CA  1 
ATOM   796   C  C   . TYR A 1 122 ? 22.441  27.36   27.369 1   42.24  ? 104 TYR H C   1 
ATOM   797   O  O   . TYR A 1 122 ? 23.569  27.726  27.755 1   43.92  ? 104 TYR H O   1 
ATOM   798   C  CB  . TYR A 1 122 ? 23.11   24.955  27.973 1   42.13  ? 104 TYR H CB  1 
ATOM   799   C  CG  . TYR A 1 122 ? 22.668  23.528  28.179 1   42.86  ? 104 TYR H CG  1 
ATOM   800   C  CD1 . TYR A 1 122 ? 22.233  23.09   29.418 1   43.26  ? 104 TYR H CD1 1 
ATOM   801   C  CD2 . TYR A 1 122 ? 22.686  22.61   27.138 1   43.22  ? 104 TYR H CD2 1 
ATOM   802   C  CE1 . TYR A 1 122 ? 21.831  21.779  29.622 1   43.83  ? 104 TYR H CE1 1 
ATOM   803   C  CE2 . TYR A 1 122 ? 22.282  21.296  27.322 1   44.26  ? 104 TYR H CE2 1 
ATOM   804   C  CZ  . TYR A 1 122 ? 21.853  20.876  28.572 1   44.86  ? 104 TYR H CZ  1 
ATOM   805   O  OH  . TYR A 1 122 ? 21.46   19.585  28.789 1   44.61  ? 104 TYR H OH  1 
ATOM   806   N  N   . ASP A 1 123 ? 21.569  28.157  26.746 1   39.41  ? 105 ASP H N   1 
ATOM   807   C  CA  . ASP A 1 123 ? 21.812  29.562  26.331 1   39.68  ? 105 ASP H CA  1 
ATOM   808   C  C   . ASP A 1 123 ? 20.841  30.465  27.106 1   39.76  ? 105 ASP H C   1 
ATOM   809   O  O   . ASP A 1 123 ? 19.611  30.226  27.043 1   38.11  ? 105 ASP H O   1 
ATOM   810   C  CB  . ASP A 1 123 ? 21.659  29.731  24.813 1   40.52  ? 105 ASP H CB  1 
ATOM   811   C  CG  . ASP A 1 123 ? 20.38   29.145  24.23  1   40.86  ? 105 ASP H CG  1 
ATOM   812   O  OD1 . ASP A 1 123 ? 19.915  28.123  24.765 1   43.35  ? 105 ASP H OD1 1 
ATOM   813   O  OD2 . ASP A 1 123 ? 19.848  29.721  23.256 1   42.02  ? 105 ASP H OD2 1 
ATOM   814   N  N   . PHE A 1 124 ? 21.371  31.471  27.801 1   38.38  ? 106 PHE H N   1 
ATOM   815   C  CA  . PHE A 1 124 ? 20.578  32.483  28.548 1   37.33  ? 106 PHE H CA  1 
ATOM   816   C  C   . PHE A 1 124 ? 19.969  33.469  27.545 1   35.6   ? 106 PHE H C   1 
ATOM   817   O  O   . PHE A 1 124 ? 20.613  34.459  27.215 1   37.03  ? 106 PHE H O   1 
ATOM   818   C  CB  . PHE A 1 124 ? 21.457  33.152  29.604 1   36.66  ? 106 PHE H CB  1 
ATOM   819   C  CG  . PHE A 1 124 ? 22.094  32.171  30.552 1   36.75  ? 106 PHE H CG  1 
ATOM   820   C  CD1 . PHE A 1 124 ? 21.309  31.358  31.356 1   37.87  ? 106 PHE H CD1 1 
ATOM   821   C  CD2 . PHE A 1 124 ? 23.471  32.048  30.631 1   37.36  ? 106 PHE H CD2 1 
ATOM   822   C  CE1 . PHE A 1 124 ? 21.889  30.448  32.228 1   38.29  ? 106 PHE H CE1 1 
ATOM   823   C  CE2 . PHE A 1 124 ? 24.05   31.145  31.511 1   38.58  ? 106 PHE H CE2 1 
ATOM   824   C  CZ  . PHE A 1 124 ? 23.259  30.345  32.307 1   37.67  ? 106 PHE H CZ  1 
ATOM   825   N  N   . GLY A 1 125 ? 18.765  33.178  27.054 1   35.51  ? 107 GLY H N   1 
ATOM   826   C  CA  . GLY A 1 125 ? 18.091  33.954  25.995 1   36.15  ? 107 GLY H CA  1 
ATOM   827   C  C   . GLY A 1 125 ? 17.383  35.19   26.531 1   36.31  ? 107 GLY H C   1 
ATOM   828   O  O   . GLY A 1 125 ? 17.258  36.171  25.773 1   37.03  ? 107 GLY H O   1 
ATOM   829   N  N   . SER A 1 126 ? 16.896  35.133  27.772 1   35.7   ? 108 SER H N   1 
ATOM   830   C  CA  . SER A 1 126 ? 16.186  36.24   28.463 1   35.29  ? 108 SER H CA  1 
ATOM   831   C  C   . SER A 1 126 ? 16.823  36.45   29.834 1   36.42  ? 108 SER H C   1 
ATOM   832   O  O   . SER A 1 126 ? 17.039  35.443  30.539 1   36.28  ? 108 SER H O   1 
ATOM   833   C  CB  . SER A 1 126 ? 14.716  35.96   28.59  1   35.1   ? 108 SER H CB  1 
ATOM   834   O  OG  . SER A 1 126 ? 14.194  35.462  27.369 1   36.07  ? 108 SER H OG  1 
ATOM   835   N  N   . TRP A 1 127 ? 17.113  37.711  30.167 1   36.5   ? 109 TRP H N   1 
ATOM   836   C  CA  . TRP A 1 127 ? 17.723  38.16   31.445 1   36.43  ? 109 TRP H CA  1 
ATOM   837   C  C   . TRP A 1 127 ? 16.805  39.191  32.098 1   37.84  ? 109 TRP H C   1 
ATOM   838   O  O   . TRP A 1 127 ? 16.145  39.928  31.356 1   39.67  ? 109 TRP H O   1 
ATOM   839   C  CB  . TRP A 1 127 ? 19.097  38.787  31.187 1   34.77  ? 109 TRP H CB  1 
ATOM   840   C  CG  . TRP A 1 127 ? 20.122  37.871  30.6   1   32.71  ? 109 TRP H CG  1 
ATOM   841   C  CD1 . TRP A 1 127 ? 20.158  37.364  29.334 1   31.31  ? 109 TRP H CD1 1 
ATOM   842   C  CD2 . TRP A 1 127 ? 21.311  37.399  31.254 1   31.75  ? 109 TRP H CD2 1 
ATOM   843   N  NE1 . TRP A 1 127 ? 21.277  36.597  29.163 1   30.78  ? 109 TRP H NE1 1 
ATOM   844   C  CE2 . TRP A 1 127 ? 22.002  36.599  30.322 1   31.02  ? 109 TRP H CE2 1 
ATOM   845   C  CE3 . TRP A 1 127 ? 21.852  37.571  32.532 1   31.75  ? 109 TRP H CE3 1 
ATOM   846   C  CZ2 . TRP A 1 127 ? 23.206  35.971  30.631 1   31.76  ? 109 TRP H CZ2 1 
ATOM   847   C  CZ3 . TRP A 1 127 ? 23.043  36.951  32.837 1   32.72  ? 109 TRP H CZ3 1 
ATOM   848   C  CH2 . TRP A 1 127 ? 23.707  36.157  31.899 1   32.21  ? 109 TRP H CH2 1 
ATOM   849   N  N   . GLY A 1 128 ? 16.815  39.277  33.429 1   40.27  ? 110 GLY H N   1 
ATOM   850   C  CA  . GLY A 1 128 ? 16.202  40.397  34.164 1   42.6   ? 110 GLY H CA  1 
ATOM   851   C  C   . GLY A 1 128 ? 17.155  41.577  34.251 1   45.2   ? 110 GLY H C   1 
ATOM   852   O  O   . GLY A 1 128 ? 18.234  41.516  33.622 1   46.85  ? 110 GLY H O   1 
ATOM   853   N  N   . GLN A 1 129 ? 16.772  42.622  34.99  1   49.36  ? 111 GLN H N   1 
ATOM   854   C  CA  . GLN A 1 129 ? 17.552  43.886  35.119 1   51.66  ? 111 GLN H CA  1 
ATOM   855   C  C   . GLN A 1 129 ? 18.678  43.689  36.148 1   47.39  ? 111 GLN H C   1 
ATOM   856   O  O   . GLN A 1 129 ? 19.646  44.472  36.11  1   47.34  ? 111 GLN H O   1 
ATOM   857   C  CB  . GLN A 1 129 ? 16.618  45.074  35.404 1   56.8   ? 111 GLN H CB  1 
ATOM   858   C  CG  . GLN A 1 129 ? 16.23   45.303  36.868 1   65.01  ? 111 GLN H CG  1 
ATOM   859   C  CD  . GLN A 1 129 ? 15.069  44.476  37.376 1   70.96  ? 111 GLN H CD  1 
ATOM   860   O  OE1 . GLN A 1 129 ? 14.411  43.749  36.631 1   76.95  ? 111 GLN H OE1 1 
ATOM   861   N  NE2 . GLN A 1 129 ? 14.802  44.583  38.67  1   71.07  ? 111 GLN H NE2 1 
ATOM   862   N  N   . GLY A 1 130 ? 18.554  42.686  37.025 1   44.43  ? 112 GLY H N   1 
ATOM   863   C  CA  . GLY A 1 130 ? 19.516  42.374  38.101 1   43.25  ? 112 GLY H CA  1 
ATOM   864   C  C   . GLY A 1 130 ? 19.107  43.013  39.421 1   41.18  ? 112 GLY H C   1 
ATOM   865   O  O   . GLY A 1 130 ? 18.352  44.007  39.39  1   40.98  ? 112 GLY H O   1 
ATOM   866   N  N   . THR A 1 131 ? 19.572  42.456  40.543 1   37.72  ? 113 THR H N   1 
ATOM   867   C  CA  . THR A 1 131 ? 19.384  43.015  41.908 1   36.69  ? 113 THR H CA  1 
ATOM   868   C  C   . THR A 1 131 ? 20.725  42.94   42.647 1   36.9   ? 113 THR H C   1 
ATOM   869   O  O   . THR A 1 131 ? 21.312  41.847  42.701 1   37.69  ? 113 THR H O   1 
ATOM   870   C  CB  . THR A 1 131 ? 18.209  42.33   42.625 1   36.41  ? 113 THR H CB  1 
ATOM   871   O  OG1 . THR A 1 131 ? 17.951  43.024  43.845 1   34.87  ? 113 THR H OG1 1 
ATOM   872   C  CG2 . THR A 1 131 ? 18.437  40.864  42.922 1   36.83  ? 113 THR H CG2 1 
ATOM   873   N  N   . LEU A 1 132 ? 21.201  44.07   43.171 1   37.76  ? 114 LEU H N   1 
ATOM   874   C  CA  . LEU A 1 132 ? 22.531  44.182  43.822 1   38.68  ? 114 LEU H CA  1 
ATOM   875   C  C   . LEU A 1 132 ? 22.403  43.758  45.289 1   39.22  ? 114 LEU H C   1 
ATOM   876   O  O   . LEU A 1 132 ? 21.636  44.41   46.02  1   40.29  ? 114 LEU H O   1 
ATOM   877   C  CB  . LEU A 1 132 ? 23.04   45.622  43.698 1   39.32  ? 114 LEU H CB  1 
ATOM   878   C  CG  . LEU A 1 132 ? 24.423  45.89   44.292 1   40.61  ? 114 LEU H CG  1 
ATOM   879   C  CD1 . LEU A 1 132 ? 25.477  45.012  43.638 1   41.11  ? 114 LEU H CD1 1 
ATOM   880   C  CD2 . LEU A 1 132 ? 24.799  47.357  44.158 1   40.76  ? 114 LEU H CD2 1 
ATOM   881   N  N   . VAL A 1 133 ? 23.114  42.696  45.679 1   40.04  ? 115 VAL H N   1 
ATOM   882   C  CA  . VAL A 1 133 ? 23.259  42.223  47.087 1   40.93  ? 115 VAL H CA  1 
ATOM   883   C  C   . VAL A 1 133 ? 24.605  42.743  47.598 1   42.03  ? 115 VAL H C   1 
ATOM   884   O  O   . VAL A 1 133 ? 25.624  42.439  46.958 1   43.94  ? 115 VAL H O   1 
ATOM   885   C  CB  . VAL A 1 133 ? 23.172  40.688  47.195 1   41.51  ? 115 VAL H CB  1 
ATOM   886   C  CG1 . VAL A 1 133 ? 23.196  40.223  48.643 1   42.71  ? 115 VAL H CG1 1 
ATOM   887   C  CG2 . VAL A 1 133 ? 21.945  40.131  46.491 1   41.92  ? 115 VAL H CG2 1 
ATOM   888   N  N   . THR A 1 134 ? 24.602  43.505  48.693 1   42.33  ? 116 THR H N   1 
ATOM   889   C  CA  . THR A 1 134 ? 25.814  44.114  49.295 1   44.22  ? 116 THR H CA  1 
ATOM   890   C  C   . THR A 1 134 ? 26.039  43.474  50.668 1   46.36  ? 116 THR H C   1 
ATOM   891   O  O   . THR A 1 134 ? 25.184  43.668  51.547 1   46.85  ? 116 THR H O   1 
ATOM   892   C  CB  . THR A 1 134 ? 25.682  45.64   49.361 1   45.61  ? 116 THR H CB  1 
ATOM   893   O  OG1 . THR A 1 134 ? 25.105  46.102  48.138 1   48.59  ? 116 THR H OG1 1 
ATOM   894   C  CG2 . THR A 1 134 ? 27.007  46.331  49.588 1   44.99  ? 116 THR H CG2 1 
ATOM   895   N  N   . VAL A 1 135 ? 27.132  42.716  50.823 1   48.62  ? 117 VAL H N   1 
ATOM   896   C  CA  . VAL A 1 135 ? 27.519  42.03   52.092 1   50.64  ? 117 VAL H CA  1 
ATOM   897   C  C   . VAL A 1 135 ? 28.579  42.889  52.786 1   51.57  ? 117 VAL H C   1 
ATOM   898   O  O   . VAL A 1 135 ? 29.7    42.977  52.258 1   52.67  ? 117 VAL H O   1 
ATOM   899   C  CB  . VAL A 1 135 ? 28.012  40.588  51.856 1   50.86  ? 117 VAL H CB  1 
ATOM   900   C  CG1 . VAL A 1 135 ? 28.15   39.836  53.174 1   50.22  ? 117 VAL H CG1 1 
ATOM   901   C  CG2 . VAL A 1 135 ? 27.094  39.825  50.909 1   50.91  ? 117 VAL H CG2 1 
ATOM   902   N  N   . SER A 1 136 ? 28.226  43.499  53.921 1   53.57  ? 118 SER H N   1 
ATOM   903   C  CA  . SER A 1 136 ? 29.061  44.509  54.622 1   56.18  ? 118 SER H CA  1 
ATOM   904   C  C   . SER A 1 136 ? 28.66   44.617  56.097 1   56.73  ? 118 SER H C   1 
ATOM   905   O  O   . SER A 1 136 ? 27.48   44.361  56.415 1   53.75  ? 118 SER H O   1 
ATOM   906   C  CB  . SER A 1 136 ? 28.963  45.844  53.922 1   57.99  ? 118 SER H CB  1 
ATOM   907   O  OG  . SER A 1 136 ? 29.548  46.882  54.699 1   58.62  ? 118 SER H OG  1 
ATOM   908   N  N   . SER A 1 137 ? 29.623  44.994  56.946 1   58.77  ? 119 SER H N   1 
ATOM   909   C  CA  . SER A 1 137 ? 29.447  45.282  58.395 1   61.03  ? 119 SER H CA  1 
ATOM   910   C  C   . SER A 1 137 ? 28.804  46.661  58.606 1   60.33  ? 119 SER H C   1 
ATOM   911   O  O   . SER A 1 137 ? 28.283  46.891  59.717 1   67.19  ? 119 SER H O   1 
ATOM   912   C  CB  . SER A 1 137 ? 30.757  45.187  59.143 1   63.65  ? 119 SER H CB  1 
ATOM   913   O  OG  . SER A 1 137 ? 31.128  43.831  59.347 1   67.66  ? 119 SER H OG  1 
ATOM   914   N  N   . ALA A 1 138 ? 28.836  47.543  57.6   1   55.58  ? 120 ALA H N   1 
ATOM   915   C  CA  . ALA A 1 138 ? 28.315  48.931  57.675 1   53.62  ? 120 ALA H CA  1 
ATOM   916   C  C   . ALA A 1 138 ? 26.788  48.923  57.836 1   51.4   ? 120 ALA H C   1 
ATOM   917   O  O   . ALA A 1 138 ? 26.202  47.829  57.831 1   47.3   ? 120 ALA H O   1 
ATOM   918   C  CB  . ALA A 1 138 ? 28.749  49.71   56.457 1   54.21  ? 120 ALA H CB  1 
ATOM   919   N  N   . SER A 1 139 ? 26.185  50.108  58.005 1   54.97  ? 121 SER H N   1 
ATOM   920   C  CA  . SER A 1 139 ? 24.732  50.333  58.251 1   54.97  ? 121 SER H CA  1 
ATOM   921   C  C   . SER A 1 139 ? 24.047  50.891  56.995 1   53.94  ? 121 SER H C   1 
ATOM   922   O  O   . SER A 1 139 ? 24.699  51.666  56.254 1   53     ? 121 SER H O   1 
ATOM   923   C  CB  . SER A 1 139 ? 24.525  51.258  59.423 1   56.89  ? 121 SER H CB  1 
ATOM   924   O  OG  . SER A 1 139 ? 24.888  50.62   60.637 1   61.06  ? 121 SER H OG  1 
ATOM   925   N  N   . THR A 1 140 ? 22.779  50.514  56.783 1   52.64  ? 122 THR H N   1 
ATOM   926   C  CA  . THR A 1 140 ? 21.88   51.056  55.727 1   52.35  ? 122 THR H CA  1 
ATOM   927   C  C   . THR A 1 140 ? 21.552  52.514  56.056 1   53.25  ? 122 THR H C   1 
ATOM   928   O  O   . THR A 1 140 ? 21.085  52.765  57.186 1   56.8   ? 122 THR H O   1 
ATOM   929   C  CB  . THR A 1 140 ? 20.576  50.257  55.606 1   51.61  ? 122 THR H CB  1 
ATOM   930   O  OG1 . THR A 1 140 ? 20.902  48.91   55.27  1   53.95  ? 122 THR H OG1 1 
ATOM   931   C  CG2 . THR A 1 140 ? 19.634  50.802  54.556 1   51.57  ? 122 THR H CG2 1 
ATOM   932   N  N   . LYS A 1 141 ? 21.783  53.421  55.105 1   52.94  ? 123 LYS H N   1 
ATOM   933   C  CA  . LYS A 1 141 ? 21.462  54.866  55.226 1   54.24  ? 123 LYS H CA  1 
ATOM   934   C  C   . LYS A 1 141 ? 20.749  55.321  53.951 1   53.86  ? 123 LYS H C   1 
ATOM   935   O  O   . LYS A 1 141 ? 21.288  55.077  52.853 1   54.27  ? 123 LYS H O   1 
ATOM   936   C  CB  . LYS A 1 141 ? 22.725  55.694  55.474 1   56.82  ? 123 LYS H CB  1 
ATOM   937   C  CG  . LYS A 1 141 ? 22.465  57.138  55.886 1   58.92  ? 123 LYS H CG  1 
ATOM   938   C  CD  . LYS A 1 141 ? 23.7    57.867  56.38  1   61.41  ? 123 LYS H CD  1 
ATOM   939   C  CE  . LYS A 1 141 ? 23.386  59.192  57.046 1   63.59  ? 123 LYS H CE  1 
ATOM   940   N  NZ  . LYS A 1 141 ? 22.817  60.174  56.092 1   63.15  ? 123 LYS H NZ  1 
ATOM   941   N  N   . GLY A 1 142 ? 19.578  55.945  54.105 1   51.66  ? 124 GLY H N   1 
ATOM   942   C  CA  . GLY A 1 142 ? 18.775  56.49   52.997 1   49.53  ? 124 GLY H CA  1 
ATOM   943   C  C   . GLY A 1 142 ? 19.335  57.828  52.525 1   47.89  ? 124 GLY H C   1 
ATOM   944   O  O   . GLY A 1 142 ? 19.964  58.545  53.304 1   45.35  ? 124 GLY H O   1 
ATOM   945   N  N   . PRO A 1 143 ? 19.128  58.204  51.242 1   47.63  ? 125 PRO H N   1 
ATOM   946   C  CA  . PRO A 1 143 ? 19.699  59.433  50.701 1   48     ? 125 PRO H CA  1 
ATOM   947   C  C   . PRO A 1 143 ? 18.917  60.69   51.1   1   47.52  ? 125 PRO H C   1 
ATOM   948   O  O   . PRO A 1 143 ? 17.738  60.587  51.349 1   48.44  ? 125 PRO H O   1 
ATOM   949   C  CB  . PRO A 1 143 ? 19.586  59.243  49.184 1   48.45  ? 125 PRO H CB  1 
ATOM   950   C  CG  . PRO A 1 143 ? 18.362  58.369  49.014 1   48.93  ? 125 PRO H CG  1 
ATOM   951   C  CD  . PRO A 1 143 ? 18.342  57.471  50.235 1   49.06  ? 125 PRO H CD  1 
ATOM   952   N  N   . SER A 1 144 ? 19.609  61.829  51.136 1   45.67  ? 126 SER H N   1 
ATOM   953   C  CA  . SER A 1 144 ? 19.023  63.189  51.077 1   45.02  ? 126 SER H CA  1 
ATOM   954   C  C   . SER A 1 144 ? 18.979  63.61   49.606 1   43.84  ? 126 SER H C   1 
ATOM   955   O  O   . SER A 1 144 ? 20.048  63.593  48.971 1   45.02  ? 126 SER H O   1 
ATOM   956   C  CB  . SER A 1 144 ? 19.818  64.161  51.911 1   46.31  ? 126 SER H CB  1 
ATOM   957   O  OG  . SER A 1 144 ? 19.957  63.683  53.242 1   47.25  ? 126 SER H OG  1 
ATOM   958   N  N   . VAL A 1 145 ? 17.79   63.935  49.088 1   41.3   ? 127 VAL H N   1 
ATOM   959   C  CA  . VAL A 1 145 ? 17.561  64.411  47.691 1   38.92  ? 127 VAL H CA  1 
ATOM   960   C  C   . VAL A 1 145 ? 17.447  65.939  47.72  1   40.27  ? 127 VAL H C   1 
ATOM   961   O  O   . VAL A 1 145 ? 16.632  66.455  48.501 1   40.96  ? 127 VAL H O   1 
ATOM   962   C  CB  . VAL A 1 145 ? 16.308  63.769  47.068 1   36.79  ? 127 VAL H CB  1 
ATOM   963   C  CG1 . VAL A 1 145 ? 16.155  64.136  45.601 1   36.93  ? 127 VAL H CG1 1 
ATOM   964   C  CG2 . VAL A 1 145 ? 16.306  62.258  47.237 1   36.33  ? 127 VAL H CG2 1 
ATOM   965   N  N   . PHE A 1 146 ? 18.24   66.629  46.898 1   42.16  ? 128 PHE H N   1 
ATOM   966   C  CA  . PHE A 1 146 ? 18.225  68.107  46.747 1   41.68  ? 128 PHE H CA  1 
ATOM   967   C  C   . PHE A 1 146 ? 18.047  68.453  45.273 1   43.18  ? 128 PHE H C   1 
ATOM   968   O  O   . PHE A 1 146 ? 18.615  67.78   44.413 1   41.8   ? 128 PHE H O   1 
ATOM   969   C  CB  . PHE A 1 146 ? 19.509  68.727  47.303 1   40.79  ? 128 PHE H CB  1 
ATOM   970   C  CG  . PHE A 1 146 ? 19.745  68.448  48.764 1   40.85  ? 128 PHE H CG  1 
ATOM   971   C  CD1 . PHE A 1 146 ? 18.91   68.99   49.731 1   41.1   ? 128 PHE H CD1 1 
ATOM   972   C  CD2 . PHE A 1 146 ? 20.789  67.632  49.177 1   40.55  ? 128 PHE H CD2 1 
ATOM   973   C  CE1 . PHE A 1 146 ? 19.113  68.718  51.076 1   40.41  ? 128 PHE H CE1 1 
ATOM   974   C  CE2 . PHE A 1 146 ? 20.996  67.37   50.524 1   40.21  ? 128 PHE H CE2 1 
ATOM   975   C  CZ  . PHE A 1 146 ? 20.16   67.915  51.471 1   39.8   ? 128 PHE H CZ  1 
ATOM   976   N  N   . PRO A 1 147 ? 17.27   69.512  44.939 1   43.42  ? 129 PRO H N   1 
ATOM   977   C  CA  . PRO A 1 147 ? 17.15   69.965  43.558 1   42.8   ? 129 PRO H CA  1 
ATOM   978   C  C   . PRO A 1 147 ? 18.426  70.694  43.125 1   42.1   ? 129 PRO H C   1 
ATOM   979   O  O   . PRO A 1 147 ? 18.926  71.491  43.884 1   40.23  ? 129 PRO H O   1 
ATOM   980   C  CB  . PRO A 1 147 ? 15.956  70.927  43.601 1   42.94  ? 129 PRO H CB  1 
ATOM   981   C  CG  . PRO A 1 147 ? 16.016  71.505  44.996 1   43.27  ? 129 PRO H CG  1 
ATOM   982   C  CD  . PRO A 1 147 ? 16.503  70.363  45.864 1   43.69  ? 129 PRO H CD  1 
ATOM   983   N  N   . LEU A 1 148 ? 18.919  70.378  41.928 1   42.87  ? 130 LEU H N   1 
ATOM   984   C  CA  . LEU A 1 148 ? 19.958  71.163  41.215 1   41.76  ? 130 LEU H CA  1 
ATOM   985   C  C   . LEU A 1 148 ? 19.23   72.072  40.225 1   42.76  ? 130 LEU H C   1 
ATOM   986   O  O   . LEU A 1 148 ? 18.867  71.584  39.13  1   44.56  ? 130 LEU H O   1 
ATOM   987   C  CB  . LEU A 1 148 ? 20.93   70.194  40.538 1   40.55  ? 130 LEU H CB  1 
ATOM   988   C  CG  . LEU A 1 148 ? 21.594  69.191  41.478 1   40.49  ? 130 LEU H CG  1 
ATOM   989   C  CD1 . LEU A 1 148 ? 22.491  68.237  40.705 1   41.06  ? 130 LEU H CD1 1 
ATOM   990   C  CD2 . LEU A 1 148 ? 22.387  69.909  42.562 1   41.61  ? 130 LEU H CD2 1 
ATOM   991   N  N   . ALA A 1 149 ? 18.976  73.322  40.635 1   42.27  ? 131 ALA H N   1 
ATOM   992   C  CA  . ALA A 1 149 ? 18.085  74.278  39.937 1   43.25  ? 131 ALA H CA  1 
ATOM   993   C  C   . ALA A 1 149 ? 18.743  74.76   38.647 1   44.89  ? 131 ALA H C   1 
ATOM   994   O  O   . ALA A 1 149 ? 19.958  74.931  38.595 1   44.9   ? 131 ALA H O   1 
ATOM   995   C  CB  . ALA A 1 149 ? 17.746  75.435  40.841 1   44.23  ? 131 ALA H CB  1 
ATOM   996   N  N   . PRO A 1 150 ? 17.966  75.003  37.566 1   47.5   ? 132 PRO H N   1 
ATOM   997   C  CA  . PRO A 1 150 ? 18.532  75.495  36.311 1   49.09  ? 132 PRO H CA  1 
ATOM   998   C  C   . PRO A 1 150 ? 18.989  76.959  36.389 1   53.24  ? 132 PRO H C   1 
ATOM   999   O  O   . PRO A 1 150 ? 18.48   77.69   37.226 1   51.79  ? 132 PRO H O   1 
ATOM   1000  C  CB  . PRO A 1 150 ? 17.384  75.338  35.304 1   47.93  ? 132 PRO H CB  1 
ATOM   1001  C  CG  . PRO A 1 150 ? 16.132  75.394  36.148 1   48.34  ? 132 PRO H CG  1 
ATOM   1002  C  CD  . PRO A 1 150 ? 16.511  74.804  37.488 1   46.99  ? 132 PRO H CD  1 
ATOM   1003  N  N   . SER A 1 151 ? 19.926  77.331  35.507 1   58.77  ? 133 SER H N   1 
ATOM   1004  C  CA  . SER A 1 151 ? 20.511  78.692  35.364 1   63.18  ? 133 SER H CA  1 
ATOM   1005  C  C   . SER A 1 151 ? 19.415  79.705  35.015 1   68.15  ? 133 SER H C   1 
ATOM   1006  O  O   . SER A 1 151 ? 18.445  79.315  34.336 1   66.27  ? 133 SER H O   1 
ATOM   1007  C  CB  . SER A 1 151 ? 21.603  78.693  34.322 1   64.13  ? 133 SER H CB  1 
ATOM   1008  O  OG  . SER A 1 151 ? 22.159  79.991  34.159 1   65.98  ? 133 SER H OG  1 
ATOM   1009  N  N   . SER A 1 152 ? 19.577  80.96   35.453 1   79.25  ? 134 SER H N   1 
ATOM   1010  C  CA  . SER A 1 152 ? 18.644  82.09   35.182 1   85.58  ? 134 SER H CA  1 
ATOM   1011  C  C   . SER A 1 152 ? 18.86   82.654  33.767 1   91.24  ? 134 SER H C   1 
ATOM   1012  O  O   . SER A 1 152 ? 17.94   83.345  33.282 1   88.13  ? 134 SER H O   1 
ATOM   1013  C  CB  . SER A 1 152 ? 18.76   83.169  36.235 1   85.8   ? 134 SER H CB  1 
ATOM   1014  O  OG  . SER A 1 152 ? 20.105  83.591  36.393 1   89.8   ? 134 SER H OG  1 
ATOM   1015  N  N   . LYS A 1 153 ? 20.017  82.371  33.145 1   100.54 ? 135 LYS H N   1 
ATOM   1016  C  CA  . LYS A 1 153 ? 20.388  82.737  31.745 1   106.9  ? 135 LYS H CA  1 
ATOM   1017  C  C   . LYS A 1 153 ? 19.166  82.64   30.818 1   114.27 ? 135 LYS H C   1 
ATOM   1018  O  O   . LYS A 1 153 ? 18.561  81.55   30.758 1   115.57 ? 135 LYS H O   1 
ATOM   1019  C  CB  . LYS A 1 153 ? 21.506  81.815  31.245 1   105.51 ? 135 LYS H CB  1 
ATOM   1020  C  CG  . LYS A 1 153 ? 22.892  82.077  31.733 0   104.65 ? 135 LYS H CG  1 
ATOM   1021  C  CD  . LYS A 1 153 ? 23.89   81.016  31.314 0   104.63 ? 135 LYS H CD  1 
ATOM   1022  C  CE  . LYS A 1 153 ? 25.232  81.15   32.001 0   104.57 ? 135 LYS H CE  1 
ATOM   1023  N  NZ  . LYS A 1 153 ? 26.138  80.031  31.65  0   104.56 ? 135 LYS H NZ  1 
ATOM   1024  N  N   . SER A 1 154 ? 18.825  83.74   30.131 1   123.62 ? 136 SER H N   1 
ATOM   1025  C  CA  . SER A 1 154 ? 17.653  83.865  29.22  1   127.59 ? 136 SER H CA  1 
ATOM   1026  C  C   . SER A 1 154 ? 17.843  82.95   28.004 1   132.47 ? 136 SER H C   1 
ATOM   1027  O  O   . SER A 1 154 ? 16.936  82.126  27.748 1   136.33 ? 136 SER H O   1 
ATOM   1028  C  CB  . SER A 1 154 ? 17.431  85.299  28.8   1   126.59 ? 136 SER H CB  1 
ATOM   1029  O  OG  . SER A 1 154 ? 18.585  85.84   28.181 0   122.19 ? 136 SER H OG  1 
ATOM   1030  N  N   . THR A 1 155 ? 18.978  83.103  27.304 1   132.47 ? 137 THR H N   1 
ATOM   1031  C  CA  . THR A 1 155 ? 19.456  82.287  26.147 1   130.78 ? 137 THR H CA  1 
ATOM   1032  C  C   . THR A 1 155 ? 18.269  81.764  25.324 1   126.49 ? 137 THR H C   1 
ATOM   1033  O  O   . THR A 1 155 ? 17.963  80.553  25.424 1   128.75 ? 137 THR H O   1 
ATOM   1034  C  CB  . THR A 1 155 ? 20.383  81.154  26.613 1   131.1  ? 137 THR H CB  1 
ATOM   1035  O  OG1 . THR A 1 155 ? 19.697  80.357  27.58  1   130.34 ? 137 THR H OG1 1 
ATOM   1036  C  CG2 . THR A 1 155 ? 21.68   81.659  27.207 1   128.8  ? 137 THR H CG2 1 
ATOM   1037  N  N   . SER A 1 156 ? 17.629  82.648  24.549 1   119.08 ? 138 SER H N   1 
ATOM   1038  C  CA  . SER A 1 156 ? 16.434  82.357  23.71  1   116.86 ? 138 SER H CA  1 
ATOM   1039  C  C   . SER A 1 156 ? 16.82   81.394  22.577 1   111.41 ? 138 SER H C   1 
ATOM   1040  O  O   . SER A 1 156 ? 17.655  81.785  21.733 1   110.04 ? 138 SER H O   1 
ATOM   1041  C  CB  . SER A 1 156 ? 15.819  83.627  23.172 1   116.89 ? 138 SER H CB  1 
ATOM   1042  O  OG  . SER A 1 156 ? 16.761  84.379  22.441 0   115.09 ? 138 SER H OG  1 
ATOM   1043  N  N   . GLY A 1 157 ? 16.245  80.184  22.577 1   102.28 ? 139 GLY H N   1 
ATOM   1044  C  CA  . GLY A 1 157 ? 16.573  79.086  21.644 1   95.42  ? 139 GLY H CA  1 
ATOM   1045  C  C   . GLY A 1 157 ? 17.533  78.068  22.246 1   92.47  ? 139 GLY H C   1 
ATOM   1046  O  O   . GLY A 1 157 ? 17.622  76.957  21.682 1   92.76  ? 139 GLY H O   1 
ATOM   1047  N  N   . GLY A 1 158 ? 18.229  78.419  23.339 1   86.79  ? 140 GLY H N   1 
ATOM   1048  C  CA  . GLY A 1 158 ? 19.237  77.574  24.011 1   78.67  ? 140 GLY H CA  1 
ATOM   1049  C  C   . GLY A 1 158 ? 18.616  76.584  24.985 1   73.45  ? 140 GLY H C   1 
ATOM   1050  O  O   . GLY A 1 158 ? 17.378  76.612  25.169 1   70.6   ? 140 GLY H O   1 
ATOM   1051  N  N   . THR A 1 159 ? 19.453  75.731  25.584 1   67.42  ? 141 THR H N   1 
ATOM   1052  C  CA  . THR A 1 159 ? 19.057  74.681  26.562 1   64.1   ? 141 THR H CA  1 
ATOM   1053  C  C   . THR A 1 159 ? 19.465  75.112  27.976 1   59.54  ? 141 THR H C   1 
ATOM   1054  O  O   . THR A 1 159 ? 20.322  76.015  28.109 1   55.13  ? 141 THR H O   1 
ATOM   1055  C  CB  . THR A 1 159 ? 19.664  73.314  26.211 1   64.01  ? 141 THR H CB  1 
ATOM   1056  O  OG1 . THR A 1 159 ? 21.087  73.43   26.226 1   64.25  ? 141 THR H OG1 1 
ATOM   1057  C  CG2 . THR A 1 159 ? 19.21   72.79   24.866 1   64.21  ? 141 THR H CG2 1 
ATOM   1058  N  N   . ALA A 1 160 ? 18.852  74.486  28.983 1   55.84  ? 142 ALA H N   1 
ATOM   1059  C  CA  . ALA A 1 160 ? 19.151  74.666  30.422 1   54.34  ? 142 ALA H CA  1 
ATOM   1060  C  C   . ALA A 1 160 ? 19.365  73.292  31.065 1   51.08  ? 142 ALA H C   1 
ATOM   1061  O  O   . ALA A 1 160 ? 18.583  72.364  30.759 1   48.53  ? 142 ALA H O   1 
ATOM   1062  C  CB  . ALA A 1 160 ? 18.033  75.424  31.094 1   53.92  ? 142 ALA H CB  1 
ATOM   1063  N  N   . ALA A 1 161 ? 20.399  73.176  31.905 1   48.16  ? 143 ALA H N   1 
ATOM   1064  C  CA  . ALA A 1 161 ? 20.7    71.981  32.725 1   47.01  ? 143 ALA H CA  1 
ATOM   1065  C  C   . ALA A 1 161 ? 20.041  72.147  34.095 1   45.38  ? 143 ALA H C   1 
ATOM   1066  O  O   . ALA A 1 161 ? 20.213  73.21   34.716 1   45.05  ? 143 ALA H O   1 
ATOM   1067  C  CB  . ALA A 1 161 ? 22.19   71.785  32.859 1   46.75  ? 143 ALA H CB  1 
ATOM   1068  N  N   . LEU A 1 162 ? 19.279  71.14   34.514 1   43.83  ? 144 LEU H N   1 
ATOM   1069  C  CA  . LEU A 1 162 ? 18.738  70.999  35.888 1   43.61  ? 144 LEU H CA  1 
ATOM   1070  C  C   . LEU A 1 162 ? 18.873  69.528  36.28  1   43.13  ? 144 LEU H C   1 
ATOM   1071  O  O   . LEU A 1 162 ? 19.009  68.694  35.372 1   44.16  ? 144 LEU H O   1 
ATOM   1072  C  CB  . LEU A 1 162 ? 17.283  71.478  35.925 1   43.74  ? 144 LEU H CB  1 
ATOM   1073  C  CG  . LEU A 1 162 ? 16.3    70.736  35.016 1   44.14  ? 144 LEU H CG  1 
ATOM   1074  C  CD1 . LEU A 1 162 ? 15.542  69.652  35.772 1   43.91  ? 144 LEU H CD1 1 
ATOM   1075  C  CD2 . LEU A 1 162 ? 15.316  71.709  34.394 1   45.25  ? 144 LEU H CD2 1 
ATOM   1076  N  N   . GLY A 1 163 ? 18.85   69.224  37.575 1   42.76  ? 145 GLY H N   1 
ATOM   1077  C  CA  . GLY A 1 163 ? 19.062  67.846  38.047 1   42.03  ? 145 GLY H CA  1 
ATOM   1078  C  C   . GLY A 1 163 ? 18.573  67.61   39.461 1   41.84  ? 145 GLY H C   1 
ATOM   1079  O  O   . GLY A 1 163 ? 17.858  68.473  40.015 1   40.89  ? 145 GLY H O   1 
ATOM   1080  N  N   . CYS A 1 164 ? 18.944  66.455  40.008 1   42.47  ? 146 CYS H N   1 
ATOM   1081  C  CA  . CYS A 1 164 ? 18.758  66.074  41.427 1   44.29  ? 146 CYS H CA  1 
ATOM   1082  C  C   . CYS A 1 164 ? 20.097  65.592  41.985 1   43.04  ? 146 CYS H C   1 
ATOM   1083  O  O   . CYS A 1 164 ? 20.829  64.915  41.247 1   43.59  ? 146 CYS H O   1 
ATOM   1084  C  CB  . CYS A 1 164 ? 17.676  65.009  41.573 1   47.88  ? 146 CYS H CB  1 
ATOM   1085  S  SG  . CYS A 1 164 ? 16.039  65.735  41.845 1   56.64  ? 146 CYS H SG  1 
ATOM   1086  N  N   . LEU A 1 165 ? 20.392  65.96   43.233 1   42.39  ? 147 LEU H N   1 
ATOM   1087  C  CA  . LEU A 1 165 ? 21.56   65.48   44.011 1   41.29  ? 147 LEU H CA  1 
ATOM   1088  C  C   . LEU A 1 165 ? 21.062  64.462  45.035 1   42.38  ? 147 LEU H C   1 
ATOM   1089  O  O   . LEU A 1 165 ? 20.386  64.889  45.99  1   44.13  ? 147 LEU H O   1 
ATOM   1090  C  CB  . LEU A 1 165 ? 22.222  66.677  44.698 1   41.05  ? 147 LEU H CB  1 
ATOM   1091  C  CG  . LEU A 1 165 ? 23.389  66.352  45.629 1   41.35  ? 147 LEU H CG  1 
ATOM   1092  C  CD1 . LEU A 1 165 ? 24.52   65.669  44.871 1   41.43  ? 147 LEU H CD1 1 
ATOM   1093  C  CD2 . LEU A 1 165 ? 23.89   67.614  46.311 1   41.28  ? 147 LEU H CD2 1 
ATOM   1094  N  N   . VAL A 1 166 ? 21.372  63.179  44.827 1   41.71  ? 148 VAL H N   1 
ATOM   1095  C  CA  . VAL A 1 166 ? 21.038  62.064  45.764 1   40.66  ? 148 VAL H CA  1 
ATOM   1096  C  C   . VAL A 1 166 ? 22.269  61.844  46.65  1   40.53  ? 148 VAL H C   1 
ATOM   1097  O  O   . VAL A 1 166 ? 23.23   61.22   46.175 1   42.01  ? 148 VAL H O   1 
ATOM   1098  C  CB  . VAL A 1 166 ? 20.623  60.79   45.005 1   40.63  ? 148 VAL H CB  1 
ATOM   1099  C  CG1 . VAL A 1 166 ? 20.102  59.728  45.959 1   41.06  ? 148 VAL H CG1 1 
ATOM   1100  C  CG2 . VAL A 1 166 ? 19.59   61.085  43.928 1   40.85  ? 148 VAL H CG2 1 
ATOM   1101  N  N   . LYS A 1 167 ? 22.213  62.326  47.895 1   40.88  ? 149 LYS H N   1 
ATOM   1102  C  CA  A LYS A 1 167 ? 23.403  62.521  48.768 0.5 42.04  ? 149 LYS H CA  1 
ATOM   1103  C  CA  B LYS A 1 167 ? 23.395  62.531  48.776 0.5 41.72  ? 149 LYS H CA  1 
ATOM   1104  C  C   . LYS A 1 167 ? 23.377  61.525  49.938 1   42.62  ? 149 LYS H C   1 
ATOM   1105  O  O   . LYS A 1 167 ? 22.294  61.348  50.542 1   43.43  ? 149 LYS H O   1 
ATOM   1106  C  CB  A LYS A 1 167 ? 23.441  63.969  49.271 0.5 42.16  ? 149 LYS H CB  1 
ATOM   1107  C  CB  B LYS A 1 167 ? 23.373  63.975  49.288 0.5 41.42  ? 149 LYS H CB  1 
ATOM   1108  C  CG  A LYS A 1 167 ? 24.817  64.62   49.254 0.5 43.26  ? 149 LYS H CG  1 
ATOM   1109  C  CG  B LYS A 1 167 ? 24.666  64.477  49.913 0.5 42.1   ? 149 LYS H CG  1 
ATOM   1110  C  CD  A LYS A 1 167 ? 24.863  65.981  49.923 0.5 44.03  ? 149 LYS H CD  1 
ATOM   1111  C  CD  B LYS A 1 167 ? 25.743  64.833  48.911 0.5 42.26  ? 149 LYS H CD  1 
ATOM   1112  C  CE  A LYS A 1 167 ? 25.064  65.901  51.422 0.5 43.67  ? 149 LYS H CE  1 
ATOM   1113  C  CE  B LYS A 1 167 ? 27.059  65.172  49.577 0.5 42.1   ? 149 LYS H CE  1 
ATOM   1114  N  NZ  A LYS A 1 167 ? 25.131  67.247  52.036 0.5 43.05  ? 149 LYS H NZ  1 
ATOM   1115  N  NZ  B LYS A 1 167 ? 28.188  65.085  48.624 0.5 43.24  ? 149 LYS H NZ  1 
ATOM   1116  N  N   . ASP A 1 168 ? 24.532  60.909  50.223 1   42.94  ? 150 ASP H N   1 
ATOM   1117  C  CA  . ASP A 1 168 ? 24.865  60.178  51.481 1   45.76  ? 150 ASP H CA  1 
ATOM   1118  C  C   . ASP A 1 168 ? 23.942  58.972  51.714 1   45.29  ? 150 ASP H C   1 
ATOM   1119  O  O   . ASP A 1 168 ? 23.252  58.94   52.756 1   47.44  ? 150 ASP H O   1 
ATOM   1120  C  CB  . ASP A 1 168 ? 24.841  61.138  52.674 1   47.16  ? 150 ASP H CB  1 
ATOM   1121  C  CG  . ASP A 1 168 ? 25.897  62.224  52.603 1   50.85  ? 150 ASP H CG  1 
ATOM   1122  O  OD1 . ASP A 1 168 ? 26.95   61.983  51.964 1   52.09  ? 150 ASP H OD1 1 
ATOM   1123  O  OD2 . ASP A 1 168 ? 25.651  63.311  53.177 1   54.28  ? 150 ASP H OD2 1 
ATOM   1124  N  N   . TYR A 1 169 ? 23.979  57.986  50.817 1   42.55  ? 151 TYR H N   1 
ATOM   1125  C  CA  . TYR A 1 169 ? 23.236  56.709  50.963 1   41.81  ? 151 TYR H CA  1 
ATOM   1126  C  C   . TYR A 1 169 ? 24.221  55.538  50.996 1   40.42  ? 151 TYR H C   1 
ATOM   1127  O  O   . TYR A 1 169 ? 25.363  55.667  50.506 1   37.99  ? 151 TYR H O   1 
ATOM   1128  C  CB  . TYR A 1 169 ? 22.194  56.542  49.854 1   43.12  ? 151 TYR H CB  1 
ATOM   1129  C  CG  . TYR A 1 169 ? 22.749  56.43   48.456 1   42.58  ? 151 TYR H CG  1 
ATOM   1130  C  CD1 . TYR A 1 169 ? 22.949  57.558  47.676 1   42.23  ? 151 TYR H CD1 1 
ATOM   1131  C  CD2 . TYR A 1 169 ? 23.064  55.194  47.909 1   41.3   ? 151 TYR H CD2 1 
ATOM   1132  C  CE1 . TYR A 1 169 ? 23.459  57.465  46.389 1   42.46  ? 151 TYR H CE1 1 
ATOM   1133  C  CE2 . TYR A 1 169 ? 23.566  55.083  46.622 1   42.16  ? 151 TYR H CE2 1 
ATOM   1134  C  CZ  . TYR A 1 169 ? 23.768  56.224  45.861 1   41.85  ? 151 TYR H CZ  1 
ATOM   1135  O  OH  . TYR A 1 169 ? 24.265  56.128  44.596 1   41.71  ? 151 TYR H OH  1 
ATOM   1136  N  N   . PHE A 1 170 ? 23.772  54.431  51.59  1   39.01  ? 152 PHE H N   1 
ATOM   1137  C  CA  . PHE A 1 170 ? 24.461  53.117  51.586 1   38.45  ? 152 PHE H CA  1 
ATOM   1138  C  C   . PHE A 1 170 ? 23.426  52.019  51.804 1   37.91  ? 152 PHE H C   1 
ATOM   1139  O  O   . PHE A 1 170 ? 22.503  52.206  52.587 1   37.24  ? 152 PHE H O   1 
ATOM   1140  C  CB  . PHE A 1 170 ? 25.54   53.063  52.668 1   39.61  ? 152 PHE H CB  1 
ATOM   1141  C  CG  . PHE A 1 170 ? 26.482  51.897  52.525 1   40.38  ? 152 PHE H CG  1 
ATOM   1142  C  CD1 . PHE A 1 170 ? 26.141  50.642  53.008 1   40.86  ? 152 PHE H CD1 1 
ATOM   1143  C  CD2 . PHE A 1 170 ? 27.689  52.046  51.859 1   41.78  ? 152 PHE H CD2 1 
ATOM   1144  C  CE1 . PHE A 1 170 ? 26.994  49.563  52.833 1   41.73  ? 152 PHE H CE1 1 
ATOM   1145  C  CE2 . PHE A 1 170 ? 28.546  50.968  51.695 1   42.59  ? 152 PHE H CE2 1 
ATOM   1146  C  CZ  . PHE A 1 170 ? 28.198  49.729  52.185 1   42     ? 152 PHE H CZ  1 
ATOM   1147  N  N   . PRO A 1 171 ? 23.505  50.85   51.129 1   39.04  ? 153 PRO H N   1 
ATOM   1148  C  CA  . PRO A 1 171 ? 24.491  50.576  50.083 1   39.24  ? 153 PRO H CA  1 
ATOM   1149  C  C   . PRO A 1 171 ? 24.038  51.163  48.741 1   40.98  ? 153 PRO H C   1 
ATOM   1150  O  O   . PRO A 1 171 ? 23.08   51.906  48.722 1   43.23  ? 153 PRO H O   1 
ATOM   1151  C  CB  . PRO A 1 171 ? 24.498  49.042  50.057 1   38.39  ? 153 PRO H CB  1 
ATOM   1152  C  CG  . PRO A 1 171 ? 23.059  48.682  50.328 1   39.4   ? 153 PRO H CG  1 
ATOM   1153  C  CD  . PRO A 1 171 ? 22.592  49.716  51.333 1   39.35  ? 153 PRO H CD  1 
ATOM   1154  N  N   . GLU A 1 172 ? 24.732  50.817  47.655 1   41.8   ? 154 GLU H N   1 
ATOM   1155  C  CA  . GLU A 1 172 ? 24.193  50.928  46.277 1   41.28  ? 154 GLU H CA  1 
ATOM   1156  C  C   . GLU A 1 172 ? 23.063  49.907  46.143 1   42.32  ? 154 GLU H C   1 
ATOM   1157  O  O   . GLU A 1 172 ? 23.009  48.955  46.928 1   44.01  ? 154 GLU H O   1 
ATOM   1158  C  CB  . GLU A 1 172 ? 25.301  50.698  45.249 1   43.2   ? 154 GLU H CB  1 
ATOM   1159  C  CG  . GLU A 1 172 ? 26.372  51.774  45.273 1   45.52  ? 154 GLU H CG  1 
ATOM   1160  C  CD  . GLU A 1 172 ? 26.613  52.462  43.94  1   46.89  ? 154 GLU H CD  1 
ATOM   1161  O  OE1 . GLU A 1 172 ? 25.704  53.206  43.494 1   46.96  ? 154 GLU H OE1 1 
ATOM   1162  O  OE2 . GLU A 1 172 ? 27.701  52.248  43.35  1   46.28  ? 154 GLU H OE2 1 
ATOM   1163  N  N   . PRO A 1 173 ? 22.125  50.038  45.169 1   40.06  ? 155 PRO H N   1 
ATOM   1164  C  CA  . PRO A 1 173 ? 22.046  51.162  44.241 1   39.46  ? 155 PRO H CA  1 
ATOM   1165  C  C   . PRO A 1 173 ? 20.921  52.166  44.53  1   40.42  ? 155 PRO H C   1 
ATOM   1166  O  O   . PRO A 1 173 ? 20.024  51.87   45.297 1   42.3   ? 155 PRO H O   1 
ATOM   1167  C  CB  . PRO A 1 173 ? 21.723  50.403  42.954 1   39.08  ? 155 PRO H CB  1 
ATOM   1168  C  CG  . PRO A 1 173 ? 20.742  49.339  43.409 1   39.33  ? 155 PRO H CG  1 
ATOM   1169  C  CD  . PRO A 1 173 ? 21.089  49.044  44.856 1   39.08  ? 155 PRO H CD  1 
ATOM   1170  N  N   . VAL A 1 174 ? 21.015  53.33   43.89  1   41.64  ? 156 VAL H N   1 
ATOM   1171  C  CA  . VAL A 1 174 ? 19.929  54.339  43.742 1   41.11  ? 156 VAL H CA  1 
ATOM   1172  C  C   . VAL A 1 174 ? 19.577  54.396  42.254 1   40.78  ? 156 VAL H C   1 
ATOM   1173  O  O   . VAL A 1 174 ? 20.516  54.415  41.434 1   40.86  ? 156 VAL H O   1 
ATOM   1174  C  CB  . VAL A 1 174 ? 20.363  55.712  44.294 1   41.7   ? 156 VAL H CB  1 
ATOM   1175  C  CG1 . VAL A 1 174 ? 19.784  56.881  43.507 1   43.87  ? 156 VAL H CG1 1 
ATOM   1176  C  CG2 . VAL A 1 174 ? 20.015  55.851  45.764 1   41.17  ? 156 VAL H CG2 1 
ATOM   1177  N  N   . THR A 1 175 ? 18.279  54.423  41.936 1   41.23  ? 157 THR H N   1 
ATOM   1178  C  CA  . THR A 1 175 ? 17.733  54.665  40.574 1   41.42  ? 157 THR H CA  1 
ATOM   1179  C  C   . THR A 1 175 ? 17.104  56.061  40.535 1   40.26  ? 157 THR H C   1 
ATOM   1180  O  O   . THR A 1 175 ? 16.614  56.52   41.58  1   38.96  ? 157 THR H O   1 
ATOM   1181  C  CB  . THR A 1 175 ? 16.71   53.595  40.176 1   42.28  ? 157 THR H CB  1 
ATOM   1182  O  OG1 . THR A 1 175 ? 15.58   53.722  41.039 1   41.89  ? 157 THR H OG1 1 
ATOM   1183  C  CG2 . THR A 1 175 ? 17.268  52.19   40.247 1   44.14  ? 157 THR H CG2 1 
ATOM   1184  N  N   . VAL A 1 176 ? 17.126  56.707  39.37  1   40.36  ? 158 VAL H N   1 
ATOM   1185  C  CA  . VAL A 1 176 ? 16.486  58.036  39.152 1   41.27  ? 158 VAL H CA  1 
ATOM   1186  C  C   . VAL A 1 176 ? 15.73   57.986  37.822 1   41.87  ? 158 VAL H C   1 
ATOM   1187  O  O   . VAL A 1 176 ? 16.369  57.71   36.793 1   43.99  ? 158 VAL H O   1 
ATOM   1188  C  CB  . VAL A 1 176 ? 17.504  59.193  39.183 1   40     ? 158 VAL H CB  1 
ATOM   1189  C  CG1 . VAL A 1 176 ? 16.8    60.54   39.172 1   39.98  ? 158 VAL H CG1 1 
ATOM   1190  C  CG2 . VAL A 1 176 ? 18.44   59.11   40.379 1   39.92  ? 158 VAL H CG2 1 
ATOM   1191  N  N   . SER A 1 177 ? 14.415  58.208  37.871 1   42.64  ? 159 SER H N   1 
ATOM   1192  C  CA  . SER A 1 177 ? 13.556  58.561  36.714 1   44.6   ? 159 SER H CA  1 
ATOM   1193  C  C   . SER A 1 177 ? 13.128  60.027  36.839 1   45.85  ? 159 SER H C   1 
ATOM   1194  O  O   . SER A 1 177 ? 13.303  60.61   37.928 1   44.96  ? 159 SER H O   1 
ATOM   1195  C  CB  . SER A 1 177 ? 12.37   57.638  36.619 1   45.81  ? 159 SER H CB  1 
ATOM   1196  O  OG  . SER A 1 177 ? 11.599  57.673  37.809 1   45.59  ? 159 SER H OG  1 
ATOM   1197  N  N   . TRP A 1 178 ? 12.606  60.597  35.751 1   48.57  ? 160 TRP H N   1 
ATOM   1198  C  CA  . TRP A 1 178 ? 12.056  61.978  35.684 1   49.16  ? 160 TRP H CA  1 
ATOM   1199  C  C   . TRP A 1 178 ? 10.619  61.923  35.16  1   49.2   ? 160 TRP H C   1 
ATOM   1200  O  O   . TRP A 1 178 ? 10.412  61.341  34.077 1   52.02  ? 160 TRP H O   1 
ATOM   1201  C  CB  . TRP A 1 178 ? 12.94   62.869  34.805 1   48.87  ? 160 TRP H CB  1 
ATOM   1202  C  CG  . TRP A 1 178 ? 14.245  63.239  35.437 1   48.37  ? 160 TRP H CG  1 
ATOM   1203  C  CD1 . TRP A 1 178 ? 15.419  62.549  35.363 1   48.58  ? 160 TRP H CD1 1 
ATOM   1204  C  CD2 . TRP A 1 178 ? 14.513  64.404  36.236 1   48.04  ? 160 TRP H CD2 1 
ATOM   1205  N  NE1 . TRP A 1 178 ? 16.399  63.205  36.057 1   47.81  ? 160 TRP H NE1 1 
ATOM   1206  C  CE2 . TRP A 1 178 ? 15.874  64.345  36.603 1   49.18  ? 160 TRP H CE2 1 
ATOM   1207  C  CE3 . TRP A 1 178 ? 13.742  65.487  36.678 1   47.87  ? 160 TRP H CE3 1 
ATOM   1208  C  CZ2 . TRP A 1 178 ? 16.474  65.326  37.392 1   49.82  ? 160 TRP H CZ2 1 
ATOM   1209  C  CZ3 . TRP A 1 178 ? 14.334  66.454  37.462 1   47.26  ? 160 TRP H CZ3 1 
ATOM   1210  C  CH2 . TRP A 1 178 ? 15.684  66.374  37.809 1   48.45  ? 160 TRP H CH2 1 
ATOM   1211  N  N   . ASN A 1 179 ? 9.672   62.505  35.904 1   47.41  ? 161 ASN H N   1 
ATOM   1212  C  CA  . ASN A 1 179 ? 8.218   62.501  35.586 1   45.18  ? 161 ASN H CA  1 
ATOM   1213  C  C   . ASN A 1 179 ? 7.751   61.048  35.397 1   45.67  ? 161 ASN H C   1 
ATOM   1214  O  O   . ASN A 1 179 ? 7.006   60.767  34.441 1   46.32  ? 161 ASN H O   1 
ATOM   1215  C  CB  . ASN A 1 179 ? 7.92    63.414  34.395 1   42.97  ? 161 ASN H CB  1 
ATOM   1216  C  CG  . ASN A 1 179 ? 8.28    64.861  34.661 1   43.24  ? 161 ASN H CG  1 
ATOM   1217  O  OD1 . ASN A 1 179 ? 8.675   65.216  35.77  1   41.74  ? 161 ASN H OD1 1 
ATOM   1218  N  ND2 . ASN A 1 179 ? 8.153   65.705  33.649 1   42.92  ? 161 ASN H ND2 1 
ATOM   1219  N  N   . SER A 1 180 ? 8.192   60.159  36.289 1   46.86  ? 162 SER H N   1 
ATOM   1220  C  CA  . SER A 1 180 ? 7.792   58.729  36.361 1   47.67  ? 162 SER H CA  1 
ATOM   1221  C  C   . SER A 1 180 ? 8.152   57.996  35.058 1   46.53  ? 162 SER H C   1 
ATOM   1222  O  O   . SER A 1 180 ? 7.399   57.084  34.665 1   47.53  ? 162 SER H O   1 
ATOM   1223  C  CB  . SER A 1 180 ? 6.328   58.627  36.701 1   47.26  ? 162 SER H CB  1 
ATOM   1224  O  OG  . SER A 1 180 ? 6.022   59.459  37.811 1   47.15  ? 162 SER H OG  1 
ATOM   1225  N  N   . GLY A 1 181 ? 9.271   58.374  34.427 1   44.37  ? 163 GLY H N   1 
ATOM   1226  C  CA  . GLY A 1 181 ? 9.822   57.711  33.23  1   44.82  ? 163 GLY H CA  1 
ATOM   1227  C  C   . GLY A 1 181 ? 9.306   58.302  31.927 1   46.02  ? 163 GLY H C   1 
ATOM   1228  O  O   . GLY A 1 181 ? 9.73    57.806  30.866 1   48.54  ? 163 GLY H O   1 
ATOM   1229  N  N   . ALA A 1 182 ? 8.447   59.328  31.984 1   44.99  ? 164 ALA H N   1 
ATOM   1230  C  CA  . ALA A 1 182 ? 7.893   60.033  30.803 1   43.86  ? 164 ALA H CA  1 
ATOM   1231  C  C   . ALA A 1 182 ? 8.991   60.85   30.106 1   46.07  ? 164 ALA H C   1 
ATOM   1232  O  O   . ALA A 1 182 ? 8.972   60.914  28.86  1   48.6   ? 164 ALA H O   1 
ATOM   1233  C  CB  . ALA A 1 182 ? 6.744   60.915  31.219 1   43.01  ? 164 ALA H CB  1 
ATOM   1234  N  N   . LEU A 1 183 ? 9.89    61.468  30.882 1   45.4   ? 165 LEU H N   1 
ATOM   1235  C  CA  . LEU A 1 183 ? 11.018  62.306  30.389 1   44.03  ? 165 LEU H CA  1 
ATOM   1236  C  C   . LEU A 1 183 ? 12.286  61.441  30.352 1   44.41  ? 165 LEU H C   1 
ATOM   1237  O  O   . LEU A 1 183 ? 12.676  60.923  31.423 1   43.19  ? 165 LEU H O   1 
ATOM   1238  C  CB  . LEU A 1 183 ? 11.163  63.516  31.323 1   43.57  ? 165 LEU H CB  1 
ATOM   1239  C  CG  . LEU A 1 183 ? 12.261  64.525  30.985 1   44.64  ? 165 LEU H CG  1 
ATOM   1240  C  CD1 . LEU A 1 183 ? 12.112  65.083  29.578 1   45.77  ? 165 LEU H CD1 1 
ATOM   1241  C  CD2 . LEU A 1 183 ? 12.261  65.663  31.993 1   45.21  ? 165 LEU H CD2 1 
ATOM   1242  N  N   . THR A 1 184 ? 12.871  61.252  29.161 1   45.42  ? 166 THR H N   1 
ATOM   1243  C  CA  . THR A 1 184 ? 14.07   60.394  28.92  1   45.94  ? 166 THR H CA  1 
ATOM   1244  C  C   . THR A 1 184 ? 15.093  61.109  28.03  1   48.41  ? 166 THR H C   1 
ATOM   1245  O  O   . THR A 1 184 ? 16.291  60.953  28.309 1   51.46  ? 166 THR H O   1 
ATOM   1246  C  CB  . THR A 1 184 ? 13.697  59.033  28.314 1   45.01  ? 166 THR H CB  1 
ATOM   1247  O  OG1 . THR A 1 184 ? 12.918  59.274  27.14  1   44.66  ? 166 THR H OG1 1 
ATOM   1248  C  CG2 . THR A 1 184 ? 12.947  58.139  29.28  1   42.25  ? 166 THR H CG2 1 
ATOM   1249  N  N   . SER A 1 185 ? 14.665  61.82   26.981 1   52.25  ? 167 SER H N   1 
ATOM   1250  C  CA  . SER A 1 185 ? 15.568  62.63   26.119 1   53.77  ? 167 SER H CA  1 
ATOM   1251  C  C   . SER A 1 185 ? 16.238  63.7    26.984 1   53.06  ? 167 SER H C   1 
ATOM   1252  O  O   . SER A 1 185 ? 15.506  64.42   27.696 1   56.34  ? 167 SER H O   1 
ATOM   1253  C  CB  . SER A 1 185 ? 14.84   63.247  24.957 1   54.72  ? 167 SER H CB  1 
ATOM   1254  O  OG  . SER A 1 185 ? 13.86   64.165  25.415 1   58.83  ? 167 SER H OG  1 
ATOM   1255  N  N   . GLY A 1 186 ? 17.573  63.755  26.96  1   52.73  ? 168 GLY H N   1 
ATOM   1256  C  CA  . GLY A 1 186 ? 18.385  64.718  27.729 1   51.87  ? 168 GLY H CA  1 
ATOM   1257  C  C   . GLY A 1 186 ? 18.746  64.209  29.117 1   50.59  ? 168 GLY H C   1 
ATOM   1258  O  O   . GLY A 1 186 ? 19.582  64.861  29.764 1   52.74  ? 168 GLY H O   1 
ATOM   1259  N  N   . VAL A 1 187 ? 18.162  63.091  29.561 1   47.96  ? 169 VAL H N   1 
ATOM   1260  C  CA  . VAL A 1 187 ? 18.409  62.505  30.909 1   46.89  ? 169 VAL H CA  1 
ATOM   1261  C  C   . VAL A 1 187 ? 19.789  61.85   30.884 1   46.49  ? 169 VAL H C   1 
ATOM   1262  O  O   . VAL A 1 187 ? 20.087  61.132  29.91  1   46.19  ? 169 VAL H O   1 
ATOM   1263  C  CB  . VAL A 1 187 ? 17.308  61.511  31.331 1   47.28  ? 169 VAL H CB  1 
ATOM   1264  C  CG1 . VAL A 1 187 ? 17.613  60.834  32.663 1   47.15  ? 169 VAL H CG1 1 
ATOM   1265  C  CG2 . VAL A 1 187 ? 15.948  62.196  31.394 1   48.46  ? 169 VAL H CG2 1 
ATOM   1266  N  N   . HIS A 1 188 ? 20.592  62.134  31.914 1   46.6   ? 170 HIS H N   1 
ATOM   1267  C  CA  . HIS A 1 188 ? 21.922  61.529  32.179 1   44.98  ? 170 HIS H CA  1 
ATOM   1268  C  C   . HIS A 1 188 ? 22.09   61.37   33.692 1   41.96  ? 170 HIS H C   1 
ATOM   1269  O  O   . HIS A 1 188 ? 22.294  62.393  34.366 1   41.24  ? 170 HIS H O   1 
ATOM   1270  C  CB  . HIS A 1 188 ? 23.032  62.374  31.534 1   47.84  ? 170 HIS H CB  1 
ATOM   1271  C  CG  . HIS A 1 188 ? 24.387  61.75   31.598 1   50     ? 170 HIS H CG  1 
ATOM   1272  N  ND1 . HIS A 1 188 ? 25.528  62.442  31.248 1   50.08  ? 170 HIS H ND1 1 
ATOM   1273  C  CD2 . HIS A 1 188 ? 24.79   60.516  31.982 1   51.93  ? 170 HIS H CD2 1 
ATOM   1274  C  CE1 . HIS A 1 188 ? 26.575  61.657  31.4   1   52.43  ? 170 HIS H CE1 1 
ATOM   1275  N  NE2 . HIS A 1 188 ? 26.15   60.467  31.851 1   52.1   ? 170 HIS H NE2 1 
ATOM   1276  N  N   . THR A 1 189 ? 21.966  60.14   34.198 1   40.29  ? 171 THR H N   1 
ATOM   1277  C  CA  . THR A 1 189 ? 22.226  59.778  35.615 1   40.43  ? 171 THR H CA  1 
ATOM   1278  C  C   . THR A 1 189 ? 23.667  59.262  35.702 1   40.97  ? 171 THR H C   1 
ATOM   1279  O  O   . THR A 1 189 ? 23.993  58.278  35.01  1   45.11  ? 171 THR H O   1 
ATOM   1280  C  CB  . THR A 1 189 ? 21.173  58.799  36.147 1   39.58  ? 171 THR H CB  1 
ATOM   1281  O  OG1 . THR A 1 189 ? 19.888  59.363  35.883 1   40.2   ? 171 THR H OG1 1 
ATOM   1282  C  CG2 . THR A 1 189 ? 21.302  58.528  37.631 1   39.62  ? 171 THR H CG2 1 
ATOM   1283  N  N   . PHE A 1 190 ? 24.493  59.919  36.515 1   39.18  ? 172 PHE H N   1 
ATOM   1284  C  CA  . PHE A 1 190 ? 25.954  59.684  36.598 1   39.59  ? 172 PHE H CA  1 
ATOM   1285  C  C   . PHE A 1 190 ? 26.22   58.543  37.57  1   39     ? 172 PHE H C   1 
ATOM   1286  O  O   . PHE A 1 190 ? 25.499  58.393  38.551 1   38.75  ? 172 PHE H O   1 
ATOM   1287  C  CB  . PHE A 1 190 ? 26.683  60.958  37.029 1   39.99  ? 172 PHE H CB  1 
ATOM   1288  C  CG  . PHE A 1 190 ? 26.82   61.987  35.937 1   39.31  ? 172 PHE H CG  1 
ATOM   1289  C  CD1 . PHE A 1 190 ? 25.709  62.66   35.453 1   38.16  ? 172 PHE H CD1 1 
ATOM   1290  C  CD2 . PHE A 1 190 ? 28.062  62.284  35.394 1   40.16  ? 172 PHE H CD2 1 
ATOM   1291  C  CE1 . PHE A 1 190 ? 25.838  63.607  34.45  1   38.56  ? 172 PHE H CE1 1 
ATOM   1292  C  CE2 . PHE A 1 190 ? 28.188  63.23   34.387 1   39.99  ? 172 PHE H CE2 1 
ATOM   1293  C  CZ  . PHE A 1 190 ? 27.076  63.889  33.917 1   39.4   ? 172 PHE H CZ  1 
ATOM   1294  N  N   . PRO A 1 191 ? 27.254  57.702  37.334 1   39.62  ? 173 PRO H N   1 
ATOM   1295  C  CA  . PRO A 1 191 ? 27.714  56.757  38.35  1   39.98  ? 173 PRO H CA  1 
ATOM   1296  C  C   . PRO A 1 191 ? 28.024  57.45   39.684 1   40.52  ? 173 PRO H C   1 
ATOM   1297  O  O   . PRO A 1 191 ? 28.544  58.556  39.683 1   41.78  ? 173 PRO H O   1 
ATOM   1298  C  CB  . PRO A 1 191 ? 28.989  56.164  37.738 1   38.61  ? 173 PRO H CB  1 
ATOM   1299  C  CG  . PRO A 1 191 ? 28.739  56.257  36.26  1   38.55  ? 173 PRO H CG  1 
ATOM   1300  C  CD  . PRO A 1 191 ? 28.009  57.572  36.077 1   38.77  ? 173 PRO H CD  1 
ATOM   1301  N  N   . ALA A 1 192 ? 27.695  56.775  40.782 1   42.34  ? 174 ALA H N   1 
ATOM   1302  C  CA  . ALA A 1 192 ? 27.845  57.287  42.162 1   42.13  ? 174 ALA H CA  1 
ATOM   1303  C  C   . ALA A 1 192 ? 29.331  57.456  42.487 1   41.76  ? 174 ALA H C   1 
ATOM   1304  O  O   . ALA A 1 192 ? 30.148  56.635  42.022 1   44.36  ? 174 ALA H O   1 
ATOM   1305  C  CB  . ALA A 1 192 ? 27.165  56.352  43.137 1   42.5   ? 174 ALA H CB  1 
ATOM   1306  N  N   . VAL A 1 193 ? 29.659  58.517  43.222 1   41.74  ? 175 VAL H N   1 
ATOM   1307  C  CA  . VAL A 1 193 ? 30.972  58.685  43.903 1   42.11  ? 175 VAL H CA  1 
ATOM   1308  C  C   . VAL A 1 193 ? 30.88   57.933  45.232 1   44.08  ? 175 VAL H C   1 
ATOM   1309  O  O   . VAL A 1 193 ? 29.841  58.05   45.898 1   44.4   ? 175 VAL H O   1 
ATOM   1310  C  CB  . VAL A 1 193 ? 31.343  60.173  44.078 1   41.46  ? 175 VAL H CB  1 
ATOM   1311  C  CG1 . VAL A 1 193 ? 30.506  60.899  45.122 1   42.02  ? 175 VAL H CG1 1 
ATOM   1312  C  CG2 . VAL A 1 193 ? 32.818  60.352  44.388 1   41.22  ? 175 VAL H CG2 1 
ATOM   1313  N  N   . LEU A 1 194 ? 31.905  57.149  45.569 1   49.06  ? 176 LEU H N   1 
ATOM   1314  C  CA  . LEU A 1 194 ? 32.124  56.628  46.945 1   49.8   ? 176 LEU H CA  1 
ATOM   1315  C  C   . LEU A 1 194 ? 32.992  57.642  47.692 1   49.84  ? 176 LEU H C   1 
ATOM   1316  O  O   . LEU A 1 194 ? 34.158  57.825  47.312 1   50.46  ? 176 LEU H O   1 
ATOM   1317  C  CB  . LEU A 1 194 ? 32.787  55.247  46.888 1   50.07  ? 176 LEU H CB  1 
ATOM   1318  C  CG  . LEU A 1 194 ? 33.119  54.595  48.233 1   48.49  ? 176 LEU H CG  1 
ATOM   1319  C  CD1 . LEU A 1 194 ? 31.99   54.751  49.247 1   47.18  ? 176 LEU H CD1 1 
ATOM   1320  C  CD2 . LEU A 1 194 ? 33.451  53.123  48.034 1   46.78  ? 176 LEU H CD2 1 
ATOM   1321  N  N   . GLN A 1 195 ? 32.421  58.292  48.702 1   53.64  ? 177 GLN H N   1 
ATOM   1322  C  CA  . GLN A 1 195 ? 33.084  59.375  49.47  1   56.6   ? 177 GLN H CA  1 
ATOM   1323  C  C   . GLN A 1 195 ? 33.968  58.741  50.553 1   56.48  ? 177 GLN H C   1 
ATOM   1324  O  O   . GLN A 1 195 ? 33.874  57.516  50.767 1   53.42  ? 177 GLN H O   1 
ATOM   1325  C  CB  . GLN A 1 195 ? 32.017  60.34   50.002 1   58.44  ? 177 GLN H CB  1 
ATOM   1326  C  CG  . GLN A 1 195 ? 31.205  60.984  48.882 1   60.69  ? 177 GLN H CG  1 
ATOM   1327  C  CD  . GLN A 1 195 ? 30.13   61.935  49.35  1   62.98  ? 177 GLN H CD  1 
ATOM   1328  O  OE1 . GLN A 1 195 ? 30.184  63.137  49.088 1   67.9   ? 177 GLN H OE1 1 
ATOM   1329  N  NE2 . GLN A 1 195 ? 29.129  61.399  50.032 1   62.97  ? 177 GLN H NE2 1 
ATOM   1330  N  N   . SER A 1 196 ? 34.805  59.558  51.197 1   59.6   ? 178 SER H N   1 
ATOM   1331  C  CA  . SER A 1 196 ? 35.728  59.173  52.298 1   58.17  ? 178 SER H CA  1 
ATOM   1332  C  C   . SER A 1 196 ? 34.943  58.635  53.503 1   55.73  ? 178 SER H C   1 
ATOM   1333  O  O   . SER A 1 196 ? 35.508  57.811  54.238 1   56.19  ? 178 SER H O   1 
ATOM   1334  C  CB  . SER A 1 196 ? 36.61   60.338  52.689 1   60.27  ? 178 SER H CB  1 
ATOM   1335  O  OG  . SER A 1 196 ? 35.85   61.522  52.887 1   59.74  ? 178 SER H OG  1 
ATOM   1336  N  N   . SER A 1 197 ? 33.692  59.076  53.691 1   53.43  ? 179 SER H N   1 
ATOM   1337  C  CA  . SER A 1 197 ? 32.78   58.643  54.787 1   51.07  ? 179 SER H CA  1 
ATOM   1338  C  C   . SER A 1 197 ? 32.321  57.19   54.603 1   48.32  ? 179 SER H C   1 
ATOM   1339  O  O   . SER A 1 197 ? 31.787  56.636  55.583 1   48.41  ? 179 SER H O   1 
ATOM   1340  C  CB  . SER A 1 197 ? 31.585  59.56   54.889 1   50.08  ? 179 SER H CB  1 
ATOM   1341  O  OG  . SER A 1 197 ? 30.86   59.575  53.669 1   49.65  ? 179 SER H OG  1 
ATOM   1342  N  N   . GLY A 1 198 ? 32.462  56.617  53.398 1   46.27  ? 180 GLY H N   1 
ATOM   1343  C  CA  . GLY A 1 198 ? 31.945  55.28   53.039 1   44.32  ? 180 GLY H CA  1 
ATOM   1344  C  C   . GLY A 1 198 ? 30.523  55.323  52.49  1   41.82  ? 180 GLY H C   1 
ATOM   1345  O  O   . GLY A 1 198 ? 30.013  54.251  52.125 1   41.84  ? 180 GLY H O   1 
ATOM   1346  N  N   . LEU A 1 199 ? 29.897  56.505  52.442 1   40.12  ? 181 LEU H N   1 
ATOM   1347  C  CA  . LEU A 1 199 ? 28.551  56.728  51.849 1   40.35  ? 181 LEU H CA  1 
ATOM   1348  C  C   . LEU A 1 199 ? 28.72   57.084  50.371 1   40     ? 181 LEU H C   1 
ATOM   1349  O  O   . LEU A 1 199 ? 29.793  57.604  50.003 1   40.65  ? 181 LEU H O   1 
ATOM   1350  C  CB  . LEU A 1 199 ? 27.83   57.856  52.596 1   40.21  ? 181 LEU H CB  1 
ATOM   1351  C  CG  . LEU A 1 199 ? 27.712  57.694  54.113 1   40.38  ? 181 LEU H CG  1 
ATOM   1352  C  CD1 . LEU A 1 199 ? 27.06   58.921  54.735 1   39.69  ? 181 LEU H CD1 1 
ATOM   1353  C  CD2 . LEU A 1 199 ? 26.938  56.434  54.481 1   38.91  ? 181 LEU H CD2 1 
ATOM   1354  N  N   . TYR A 1 200 ? 27.696  56.804  49.562 1   38.7   ? 182 TYR H N   1 
ATOM   1355  C  CA  . TYR A 1 200 ? 27.641  57.174  48.127 1   38.84  ? 182 TYR H CA  1 
ATOM   1356  C  C   . TYR A 1 200 ? 26.83   58.457  47.964 1   37.83  ? 182 TYR H C   1 
ATOM   1357  O  O   . TYR A 1 200 ? 25.916  58.696  48.762 1   39.4   ? 182 TYR H O   1 
ATOM   1358  C  CB  . TYR A 1 200 ? 27.033  56.053  47.289 1   39.19  ? 182 TYR H CB  1 
ATOM   1359  C  CG  . TYR A 1 200 ? 27.826  54.774  47.286 1   39.7   ? 182 TYR H CG  1 
ATOM   1360  C  CD1 . TYR A 1 200 ? 28.863  54.569  46.387 1   39.29  ? 182 TYR H CD1 1 
ATOM   1361  C  CD2 . TYR A 1 200 ? 27.529  53.756  48.179 1   40.44  ? 182 TYR H CD2 1 
ATOM   1362  C  CE1 . TYR A 1 200 ? 29.588  53.386  46.38  1   39.22  ? 182 TYR H CE1 1 
ATOM   1363  C  CE2 . TYR A 1 200 ? 28.245  52.569  48.186 1   40.77  ? 182 TYR H CE2 1 
ATOM   1364  C  CZ  . TYR A 1 200 ? 29.278  52.382  47.283 1   39.49  ? 182 TYR H CZ  1 
ATOM   1365  O  OH  . TYR A 1 200 ? 29.967  51.205  47.297 1   40.63  ? 182 TYR H OH  1 
ATOM   1366  N  N   . SER A 1 201 ? 27.185  59.255  46.958 1   38.25  ? 183 SER H N   1 
ATOM   1367  C  CA  . SER A 1 201 ? 26.358  60.35   46.387 1   38.87  ? 183 SER H CA  1 
ATOM   1368  C  C   . SER A 1 201 ? 26.358  60.22   44.858 1   38.44  ? 183 SER H C   1 
ATOM   1369  O  O   . SER A 1 201 ? 27.416  59.879  44.301 1   36.8   ? 183 SER H O   1 
ATOM   1370  C  CB  . SER A 1 201 ? 26.861  61.703  46.816 1   39.05  ? 183 SER H CB  1 
ATOM   1371  O  OG  . SER A 1 201 ? 27.089  61.752  48.218 1   40.16  ? 183 SER H OG  1 
ATOM   1372  N  N   . LEU A 1 202 ? 25.217  60.438  44.202 1   38.23  ? 184 LEU H N   1 
ATOM   1373  C  CA  . LEU A 1 202 ? 25.177  60.643  42.729 1   38.49  ? 184 LEU H CA  1 
ATOM   1374  C  C   . LEU A 1 202 ? 24.339  61.876  42.404 1   38.33  ? 184 LEU H C   1 
ATOM   1375  O  O   . LEU A 1 202 ? 23.719  62.461  43.318 1   38.04  ? 184 LEU H O   1 
ATOM   1376  C  CB  . LEU A 1 202 ? 24.663  59.398  41.996 1   38.45  ? 184 LEU H CB  1 
ATOM   1377  C  CG  . LEU A 1 202 ? 23.25   58.911  42.307 1   38.38  ? 184 LEU H CG  1 
ATOM   1378  C  CD1 . LEU A 1 202 ? 22.183  59.783  41.661 1   39.81  ? 184 LEU H CD1 1 
ATOM   1379  C  CD2 . LEU A 1 202 ? 23.085  57.478  41.828 1   38.41  ? 184 LEU H CD2 1 
ATOM   1380  N  N   . SER A 1 203 ? 24.363  62.245  41.127 1   38.35  ? 185 SER H N   1 
ATOM   1381  C  CA  . SER A 1 203 ? 23.516  63.296  40.518 1   38.24  ? 185 SER H CA  1 
ATOM   1382  C  C   . SER A 1 203 ? 22.884  62.735  39.244 1   38.09  ? 185 SER H C   1 
ATOM   1383  O  O   . SER A 1 203 ? 23.515  61.88   38.577 1   35.9   ? 185 SER H O   1 
ATOM   1384  C  CB  . SER A 1 203 ? 24.309  64.551  40.248 1   37.69  ? 185 SER H CB  1 
ATOM   1385  O  OG  . SER A 1 203 ? 24.982  64.984  41.422 1   35.16  ? 185 SER H OG  1 
ATOM   1386  N  N   . SER A 1 204 ? 21.658  63.171  38.966 1   39.13  ? 186 SER H N   1 
ATOM   1387  C  CA  . SER A 1 204 ? 20.937  62.958  37.688 1   40.31  ? 186 SER H CA  1 
ATOM   1388  C  C   . SER A 1 204 ? 20.621  64.334  37.109 1   39.83  ? 186 SER H C   1 
ATOM   1389  O  O   . SER A 1 204 ? 19.996  65.117  37.822 1   40.44  ? 186 SER H O   1 
ATOM   1390  C  CB  . SER A 1 204 ? 19.696  62.14   37.9   1   39.74  ? 186 SER H CB  1 
ATOM   1391  O  OG  . SER A 1 204 ? 19.177  61.71   36.659 1   40.85  ? 186 SER H OG  1 
ATOM   1392  N  N   . VAL A 1 205 ? 21.106  64.628  35.903 1   41.84  ? 187 VAL H N   1 
ATOM   1393  C  CA  . VAL A 1 205 ? 20.897  65.928  35.201 1   43.6   ? 187 VAL H CA  1 
ATOM   1394  C  C   . VAL A 1 205 ? 20.029  65.67   33.964 1   45.03  ? 187 VAL H C   1 
ATOM   1395  O  O   . VAL A 1 205 ? 20.134  64.57   33.379 1   45.59  ? 187 VAL H O   1 
ATOM   1396  C  CB  . VAL A 1 205 ? 22.239  66.601  34.842 1   45.22  ? 187 VAL H CB  1 
ATOM   1397  C  CG1 . VAL A 1 205 ? 22.961  65.903  33.696 1   45.65  ? 187 VAL H CG1 1 
ATOM   1398  C  CG2 . VAL A 1 205 ? 22.063  68.085  34.539 1   44.44  ? 187 VAL H CG2 1 
ATOM   1399  N  N   . VAL A 1 206 ? 19.195  66.642  33.592 1   45.54  ? 188 VAL H N   1 
ATOM   1400  C  CA  . VAL A 1 206 ? 18.4    66.617  32.331 1   45.75  ? 188 VAL H CA  1 
ATOM   1401  C  C   . VAL A 1 206 ? 18.59   67.962  31.614 1   47.28  ? 188 VAL H C   1 
ATOM   1402  O  O   . VAL A 1 206 ? 18.519  69.017  32.276 1   44.43  ? 188 VAL H O   1 
ATOM   1403  C  CB  . VAL A 1 206 ? 16.923  66.257  32.585 1   45.78  ? 188 VAL H CB  1 
ATOM   1404  C  CG1 . VAL A 1 206 ? 16.208  67.264  33.469 1   46.57  ? 188 VAL H CG1 1 
ATOM   1405  C  CG2 . VAL A 1 206 ? 16.162  66.04   31.284 1   46.47  ? 188 VAL H CG2 1 
ATOM   1406  N  N   . THR A 1 207 ? 18.892  67.897  30.316 1   50.81  ? 189 THR H N   1 
ATOM   1407  C  CA  . THR A 1 207 ? 18.986  69.05   29.385 1   51.51  ? 189 THR H CA  1 
ATOM   1408  C  C   . THR A 1 207 ? 17.594  69.268  28.787 1   51.12  ? 189 THR H C   1 
ATOM   1409  O  O   . THR A 1 207 ? 17.004  68.283  28.283 1   51.51  ? 189 THR H O   1 
ATOM   1410  C  CB  . THR A 1 207 ? 20.066  68.796  28.325 1   53.35  ? 189 THR H CB  1 
ATOM   1411  O  OG1 . THR A 1 207 ? 21.289  68.55   29.017 1   53.39  ? 189 THR H OG1 1 
ATOM   1412  C  CG2 . THR A 1 207 ? 20.261  69.951  27.369 1   56.65  ? 189 THR H CG2 1 
ATOM   1413  N  N   . VAL A 1 208 ? 17.073  70.494  28.884 1   49.21  ? 190 VAL H N   1 
ATOM   1414  C  CA  . VAL A 1 208 ? 15.702  70.87   28.426 1   47.53  ? 190 VAL H CA  1 
ATOM   1415  C  C   . VAL A 1 208 ? 15.762  72.268  27.814 1   48.01  ? 190 VAL H C   1 
ATOM   1416  O  O   . VAL A 1 208 ? 16.735  72.987  28.032 1   46.71  ? 190 VAL H O   1 
ATOM   1417  C  CB  . VAL A 1 208 ? 14.692  70.791  29.588 1   45.37  ? 190 VAL H CB  1 
ATOM   1418  C  CG1 . VAL A 1 208 ? 14.555  69.369  30.103 1   45.86  ? 190 VAL H CG1 1 
ATOM   1419  C  CG2 . VAL A 1 208 ? 15.038  71.736  30.73  1   45.48  ? 190 VAL H CG2 1 
ATOM   1420  N  N   . PRO A 1 209 ? 14.742  72.704  27.036 1   49.96  ? 191 PRO H N   1 
ATOM   1421  C  CA  . PRO A 1 209 ? 14.722  74.07   26.504 1   51.99  ? 191 PRO H CA  1 
ATOM   1422  C  C   . PRO A 1 209 ? 14.627  75.142  27.606 1   51.86  ? 191 PRO H C   1 
ATOM   1423  O  O   . PRO A 1 209 ? 13.852  74.959  28.529 1   52.39  ? 191 PRO H O   1 
ATOM   1424  C  CB  . PRO A 1 209 ? 13.476  74.105  25.602 1   52.28  ? 191 PRO H CB  1 
ATOM   1425  C  CG  . PRO A 1 209 ? 13.145  72.643  25.344 1   51.71  ? 191 PRO H CG  1 
ATOM   1426  C  CD  . PRO A 1 209 ? 13.577  71.917  26.599 1   49.2   ? 191 PRO H CD  1 
ATOM   1427  N  N   . SER A 1 210 ? 15.425  76.209  27.485 1   53.04  ? 192 SER H N   1 
ATOM   1428  C  CA  . SER A 1 210 ? 15.441  77.399  28.381 1   55.74  ? 192 SER H CA  1 
ATOM   1429  C  C   . SER A 1 210 ? 14.059  78.06   28.433 1   56.89  ? 192 SER H C   1 
ATOM   1430  O  O   . SER A 1 210 ? 13.627  78.438  29.54  1   54.25  ? 192 SER H O   1 
ATOM   1431  C  CB  . SER A 1 210 ? 16.464  78.398  27.928 1   57.55  ? 192 SER H CB  1 
ATOM   1432  O  OG  . SER A 1 210 ? 17.753  77.813  27.895 1   64.55  ? 192 SER H OG  1 
ATOM   1433  N  N   . SER A 1 211 ? 13.411  78.201  27.268 1   59.34  ? 193 SER H N   1 
ATOM   1434  C  CA  . SER A 1 211 ? 12.106  78.889  27.058 1   58.88  ? 193 SER H CA  1 
ATOM   1435  C  C   . SER A 1 211 ? 10.979  78.234  27.871 1   59.79  ? 193 SER H C   1 
ATOM   1436  O  O   . SER A 1 211 ? 10.009  78.948  28.188 1   62.73  ? 193 SER H O   1 
ATOM   1437  C  CB  . SER A 1 211 ? 11.756  78.917  25.595 1   56.46  ? 193 SER H CB  1 
ATOM   1438  O  OG  . SER A 1 211 ? 11.73   77.6    25.065 1   54.65  ? 193 SER H OG  1 
ATOM   1439  N  N   . SER A 1 212 ? 11.104  76.941  28.194 1   59.19  ? 194 SER H N   1 
ATOM   1440  C  CA  . SER A 1 212 ? 10.052  76.087  28.808 1   59.67  ? 194 SER H CA  1 
ATOM   1441  C  C   . SER A 1 212 ? 10.186  75.988  30.342 1   58.22  ? 194 SER H C   1 
ATOM   1442  O  O   . SER A 1 212 ? 9.444   75.174  30.93  1   58.67  ? 194 SER H O   1 
ATOM   1443  C  CB  . SER A 1 212 ? 10.104  74.714  28.176 1   61.47  ? 194 SER H CB  1 
ATOM   1444  O  OG  . SER A 1 212 ? 11.177  73.942  28.715 1   62.2   ? 194 SER H OG  1 
ATOM   1445  N  N   . LEU A 1 213 ? 11.077  76.759  30.98  1   56.33  ? 195 LEU H N   1 
ATOM   1446  C  CA  . LEU A 1 213 ? 11.508  76.513  32.389 1   56.01  ? 195 LEU H CA  1 
ATOM   1447  C  C   . LEU A 1 213 ? 10.406  76.894  33.385 1   57.08  ? 195 LEU H C   1 
ATOM   1448  O  O   . LEU A 1 213 ? 10.267  76.172  34.395 1   58.29  ? 195 LEU H O   1 
ATOM   1449  C  CB  . LEU A 1 213 ? 12.805  77.271  32.701 1   54.35  ? 195 LEU H CB  1 
ATOM   1450  C  CG  . LEU A 1 213 ? 14.102  76.582  32.276 1   53.66  ? 195 LEU H CG  1 
ATOM   1451  C  CD1 . LEU A 1 213 ? 15.296  77.483  32.558 1   53.33  ? 195 LEU H CD1 1 
ATOM   1452  C  CD2 . LEU A 1 213 ? 14.278  75.238  32.972 1   51.35  ? 195 LEU H CD2 1 
ATOM   1453  N  N   . GLY A 1 214 ? 9.672   77.981  33.131 1   58.74  ? 196 GLY H N   1 
ATOM   1454  C  CA  . GLY A 1 214 ? 8.592   78.466  34.014 1   63.09  ? 196 GLY H CA  1 
ATOM   1455  C  C   . GLY A 1 214 ? 7.317   77.641  33.899 1   63.76  ? 196 GLY H C   1 
ATOM   1456  O  O   . GLY A 1 214 ? 6.51    77.664  34.856 1   67.94  ? 196 GLY H O   1 
ATOM   1457  N  N   . THR A 1 215 ? 7.147   76.933  32.777 1   60.43  ? 197 THR H N   1 
ATOM   1458  C  CA  . THR A 1 215 ? 5.886   76.281  32.334 1   55.95  ? 197 THR H CA  1 
ATOM   1459  C  C   . THR A 1 215 ? 5.914   74.784  32.667 1   54.59  ? 197 THR H C   1 
ATOM   1460  O  O   . THR A 1 215 ? 4.925   74.287  33.238 1   55.75  ? 197 THR H O   1 
ATOM   1461  C  CB  . THR A 1 215 ? 5.695   76.513  30.83  1   54.08  ? 197 THR H CB  1 
ATOM   1462  O  OG1 . THR A 1 215 ? 6.697   75.782  30.124 1   53.35  ? 197 THR H OG1 1 
ATOM   1463  C  CG2 . THR A 1 215 ? 5.783   77.972  30.439 1   54.24  ? 197 THR H CG2 1 
ATOM   1464  N  N   . GLN A 1 216 ? 7.004   74.103  32.298 1   51.8   ? 198 GLN H N   1 
ATOM   1465  C  CA  . GLN A 1 216 ? 7.174   72.63   32.409 1   51.45  ? 198 GLN H CA  1 
ATOM   1466  C  C   . GLN A 1 216 ? 7.546   72.257  33.848 1   48.42  ? 198 GLN H C   1 
ATOM   1467  O  O   . GLN A 1 216 ? 8.436   72.914  34.42  1   49.74  ? 198 GLN H O   1 
ATOM   1468  C  CB  . GLN A 1 216 ? 8.274   72.144  31.461 1   53.08  ? 198 GLN H CB  1 
ATOM   1469  C  CG  . GLN A 1 216 ? 7.982   72.398  29.99  1   53.07  ? 198 GLN H CG  1 
ATOM   1470  C  CD  . GLN A 1 216 ? 6.937   71.449  29.46  1   52.64  ? 198 GLN H CD  1 
ATOM   1471  O  OE1 . GLN A 1 216 ? 7.161   70.243  29.391 1   56.86  ? 198 GLN H OE1 1 
ATOM   1472  N  NE2 . GLN A 1 216 ? 5.786   71.981  29.085 1   52.41  ? 198 GLN H NE2 1 
ATOM   1473  N  N   . THR A 1 217 ? 6.9     71.224  34.391 1   45.23  ? 199 THR H N   1 
ATOM   1474  C  CA  . THR A 1 217 ? 7.197   70.638  35.723 1   43.93  ? 199 THR H CA  1 
ATOM   1475  C  C   . THR A 1 217 ? 8.189   69.49   35.525 1   44.36  ? 199 THR H C   1 
ATOM   1476  O  O   . THR A 1 217 ? 7.913   68.607  34.682 1   43.88  ? 199 THR H O   1 
ATOM   1477  C  CB  . THR A 1 217 ? 5.913   70.203  36.438 1   43.5   ? 199 THR H CB  1 
ATOM   1478  O  OG1 . THR A 1 217 ? 5.171   71.399  36.673 1   44.79  ? 199 THR H OG1 1 
ATOM   1479  C  CG2 . THR A 1 217 ? 6.153   69.475  37.743 1   43.83  ? 199 THR H CG2 1 
ATOM   1480  N  N   . TYR A 1 218 ? 9.301   69.534  36.265 1   44.33  ? 200 TYR H N   1 
ATOM   1481  C  CA  . TYR A 1 218 ? 10.378  68.513  36.289 1   43.07  ? 200 TYR H CA  1 
ATOM   1482  C  C   . TYR A 1 218 ? 10.475  67.958  37.71  1   42.5   ? 200 TYR H C   1 
ATOM   1483  O  O   . TYR A 1 218 ? 10.903  68.698  38.615 1   41.35  ? 200 TYR H O   1 
ATOM   1484  C  CB  . TYR A 1 218 ? 11.7    69.12   35.816 1   42.34  ? 200 TYR H CB  1 
ATOM   1485  C  CG  . TYR A 1 218 ? 11.65   69.672  34.415 1   41.96  ? 200 TYR H CG  1 
ATOM   1486  C  CD1 . TYR A 1 218 ? 11.531  68.829  33.321 1   41     ? 200 TYR H CD1 1 
ATOM   1487  C  CD2 . TYR A 1 218 ? 11.721  71.035  34.179 1   41.5   ? 200 TYR H CD2 1 
ATOM   1488  C  CE1 . TYR A 1 218 ? 11.481  69.326  32.027 1   42.11  ? 200 TYR H CE1 1 
ATOM   1489  C  CE2 . TYR A 1 218 ? 11.672  71.549  32.892 1   41.89  ? 200 TYR H CE2 1 
ATOM   1490  C  CZ  . TYR A 1 218 ? 11.551  70.694  31.811 1   42.26  ? 200 TYR H CZ  1 
ATOM   1491  O  OH  . TYR A 1 218 ? 11.51   71.211  30.546 1   41.64  ? 200 TYR H OH  1 
ATOM   1492  N  N   . ILE A 1 219 ? 10.053  66.702  37.881 1   43.22  ? 201 ILE H N   1 
ATOM   1493  C  CA  . ILE A 1 219 ? 10.11   65.929  39.155 1   42.65  ? 201 ILE H CA  1 
ATOM   1494  C  C   . ILE A 1 219 ? 11.073  64.759  38.931 1   44.46  ? 201 ILE H C   1 
ATOM   1495  O  O   . ILE A 1 219 ? 10.831  63.974  37.993 1   45.34  ? 201 ILE H O   1 
ATOM   1496  C  CB  . ILE A 1 219 ? 8.697   65.455  39.567 1   40.96  ? 201 ILE H CB  1 
ATOM   1497  C  CG1 . ILE A 1 219 ? 7.74    66.627  39.82  1   40.35  ? 201 ILE H CG1 1 
ATOM   1498  C  CG2 . ILE A 1 219 ? 8.752   64.525  40.77  1   40.26  ? 201 ILE H CG2 1 
ATOM   1499  C  CD1 . ILE A 1 219 ? 6.292   66.303  39.665 0   39.74  ? 201 ILE H CD1 1 
ATOM   1500  N  N   . CYS A 1 220 ? 12.129  64.657  39.742 1   46.37  ? 202 CYS H N   1 
ATOM   1501  C  CA  . CYS A 1 220 ? 13.005  63.459  39.817 1   47.3   ? 202 CYS H CA  1 
ATOM   1502  C  C   . CYS A 1 220 ? 12.405  62.488  40.84  1   46.73  ? 202 CYS H C   1 
ATOM   1503  O  O   . CYS A 1 220 ? 11.986  62.952  41.924 1   43.98  ? 202 CYS H O   1 
ATOM   1504  C  CB  . CYS A 1 220 ? 14.446  63.818  40.161 1   50.53  ? 202 CYS H CB  1 
ATOM   1505  S  SG  . CYS A 1 220 ? 14.741  64.168  41.915 1   53.88  ? 202 CYS H SG  1 
ATOM   1506  N  N   . ASN A 1 221 ? 12.354  61.2    40.487 1   46.51  ? 203 ASN H N   1 
ATOM   1507  C  CA  . ASN A 1 221 ? 11.789  60.105  41.32  1   45.72  ? 203 ASN H CA  1 
ATOM   1508  C  C   . ASN A 1 221 ? 12.963  59.218  41.736 1   46.36  ? 203 ASN H C   1 
ATOM   1509  O  O   . ASN A 1 221 ? 13.471  58.454  40.884 1   44.54  ? 203 ASN H O   1 
ATOM   1510  C  CB  . ASN A 1 221 ? 10.687  59.336  40.588 1   45.86  ? 203 ASN H CB  1 
ATOM   1511  C  CG  . ASN A 1 221 ? 9.927   60.197  39.602 1   47.46  ? 203 ASN H CG  1 
ATOM   1512  O  OD1 . ASN A 1 221 ? 10.249  60.22   38.415 1   47.85  ? 203 ASN H OD1 1 
ATOM   1513  N  ND2 . ASN A 1 221 ? 8.938   60.93   40.087 1   48.8   ? 203 ASN H ND2 1 
ATOM   1514  N  N   . VAL A 1 222 ? 13.418  59.376  42.981 1   46.65  ? 204 VAL H N   1 
ATOM   1515  C  CA  . VAL A 1 222 ? 14.603  58.664  43.536 1   45.97  ? 204 VAL H CA  1 
ATOM   1516  C  C   . VAL A 1 222 ? 14.089  57.433  44.277 1   47.15  ? 204 VAL H C   1 
ATOM   1517  O  O   . VAL A 1 222 ? 13.206  57.583  45.138 1   46.98  ? 204 VAL H O   1 
ATOM   1518  C  CB  . VAL A 1 222 ? 15.441  59.579  44.447 1   45.52  ? 204 VAL H CB  1 
ATOM   1519  C  CG1 . VAL A 1 222 ? 16.652  58.861  45.027 1   45.15  ? 204 VAL H CG1 1 
ATOM   1520  C  CG2 . VAL A 1 222 ? 15.876  60.837  43.71  1   46.68  ? 204 VAL H CG2 1 
ATOM   1521  N  N   . ASN A 1 223 ? 14.605  56.26   43.92  1   49.47  ? 205 ASN H N   1 
ATOM   1522  C  CA  . ASN A 1 223 ? 14.344  54.995  44.645 1   51.64  ? 205 ASN H CA  1 
ATOM   1523  C  C   . ASN A 1 223 ? 15.679  54.497  45.197 1   49.58  ? 205 ASN H C   1 
ATOM   1524  O  O   . ASN A 1 223 ? 16.601  54.281  44.4   1   50.09  ? 205 ASN H O   1 
ATOM   1525  C  CB  . ASN A 1 223 ? 13.653  53.956  43.759 1   54.88  ? 205 ASN H CB  1 
ATOM   1526  C  CG  . ASN A 1 223 ? 12.806  52.979  44.547 1   60.12  ? 205 ASN H CG  1 
ATOM   1527  O  OD1 . ASN A 1 223 ? 13.092  52.692  45.71  1   63.42  ? 205 ASN H OD1 1 
ATOM   1528  N  ND2 . ASN A 1 223 ? 11.759  52.458  43.925 1   63.49  ? 205 ASN H ND2 1 
ATOM   1529  N  N   . HIS A 1 224 ? 15.769  54.399  46.522 1   47.65  ? 206 HIS H N   1 
ATOM   1530  C  CA  . HIS A 1 224 ? 16.789  53.623  47.268 1   46.06  ? 206 HIS H CA  1 
ATOM   1531  C  C   . HIS A 1 224 ? 16.061  52.444  47.93  1   47.46  ? 206 HIS H C   1 
ATOM   1532  O  O   . HIS A 1 224 ? 15.542  52.622  49.052 1   43.32  ? 206 HIS H O   1 
ATOM   1533  C  CB  . HIS A 1 224 ? 17.533  54.553  48.237 1   43.76  ? 206 HIS H CB  1 
ATOM   1534  C  CG  . HIS A 1 224 ? 18.706  53.911  48.889 1   41.18  ? 206 HIS H CG  1 
ATOM   1535  N  ND1 . HIS A 1 224 ? 18.844  53.847  50.252 1   41.72  ? 206 HIS H ND1 1 
ATOM   1536  C  CD2 . HIS A 1 224 ? 19.775  53.273  48.371 1   40.48  ? 206 HIS H CD2 1 
ATOM   1537  C  CE1 . HIS A 1 224 ? 19.956  53.213  50.552 1   41.68  ? 206 HIS H CE1 1 
ATOM   1538  N  NE2 . HIS A 1 224 ? 20.546  52.854  49.415 1   40.57  ? 206 HIS H NE2 1 
ATOM   1539  N  N   . LYS A 1 225 ? 15.979  51.305  47.229 1   50.88  ? 207 LYS H N   1 
ATOM   1540  C  CA  A LYS A 1 225 ? 15.203  50.109  47.669 0.5 52.92  ? 207 LYS H CA  1 
ATOM   1541  C  CA  B LYS A 1 225 ? 15.197  50.117  47.676 0.5 53.36  ? 207 LYS H CA  1 
ATOM   1542  C  C   . LYS A 1 225 ? 15.802  49.537  48.954 1   53.67  ? 207 LYS H C   1 
ATOM   1543  O  O   . LYS A 1 225 ? 15.062  49.169  49.864 1   55     ? 207 LYS H O   1 
ATOM   1544  C  CB  A LYS A 1 225 ? 15.131  49.061  46.552 0.5 53.25  ? 207 LYS H CB  1 
ATOM   1545  C  CB  B LYS A 1 225 ? 15.08   49.072  46.558 0.5 54.28  ? 207 LYS H CB  1 
ATOM   1546  C  CG  A LYS A 1 225 ? 14.247  49.438  45.369 0.5 53.87  ? 207 LYS H CG  1 
ATOM   1547  C  CG  B LYS A 1 225 ? 14.053  49.406  45.483 0.5 55.44  ? 207 LYS H CG  1 
ATOM   1548  C  CD  A LYS A 1 225 ? 14.529  48.628  44.117 0.5 53.73  ? 207 LYS H CD  1 
ATOM   1549  C  CD  B LYS A 1 225 ? 13.769  48.267  44.521 0.5 56.19  ? 207 LYS H CD  1 
ATOM   1550  C  CE  A LYS A 1 225 ? 13.683  49.031  42.928 0.5 53.33  ? 207 LYS H CE  1 
ATOM   1551  C  CE  B LYS A 1 225 ? 12.76   48.63   43.449 0.5 55.97  ? 207 LYS H CE  1 
ATOM   1552  N  NZ  A LYS A 1 225 ? 14.216  48.465  41.666 0.5 52.31  ? 207 LYS H NZ  1 
ATOM   1553  N  NZ  B LYS A 1 225 ? 11.453  49.014  44.031 0.5 55.27  ? 207 LYS H NZ  1 
ATOM   1554  N  N   . PRO A 1 226 ? 17.149  49.447  49.096 1   54.35  ? 208 PRO H N   1 
ATOM   1555  C  CA  . PRO A 1 226 ? 17.75   48.942  50.333 1   54.22  ? 208 PRO H CA  1 
ATOM   1556  C  C   . PRO A 1 226 ? 17.29   49.608  51.639 1   55.5   ? 208 PRO H C   1 
ATOM   1557  O  O   . PRO A 1 226 ? 17.282  48.921  52.64  1   55.41  ? 208 PRO H O   1 
ATOM   1558  C  CB  . PRO A 1 226 ? 19.241  49.227  50.126 1   54.45  ? 208 PRO H CB  1 
ATOM   1559  C  CG  . PRO A 1 226 ? 19.417  49.096  48.639 1   55.21  ? 208 PRO H CG  1 
ATOM   1560  C  CD  . PRO A 1 226 ? 18.174  49.754  48.082 1   56.04  ? 208 PRO H CD  1 
ATOM   1561  N  N   . SER A 1 227 ? 16.939  50.899  51.598 1   59.36  ? 209 SER H N   1 
ATOM   1562  C  CA  . SER A 1 227 ? 16.448  51.699  52.755 1   60.99  ? 209 SER H CA  1 
ATOM   1563  C  C   . SER A 1 227 ? 14.926  51.901  52.691 1   64.98  ? 209 SER H C   1 
ATOM   1564  O  O   . SER A 1 227 ? 14.396  52.583  53.597 1   67.23  ? 209 SER H O   1 
ATOM   1565  C  CB  . SER A 1 227 ? 17.158  53.027  52.818 1   61.61  ? 209 SER H CB  1 
ATOM   1566  O  OG  . SER A 1 227 ? 16.695  53.905  51.8   1   60.61  ? 209 SER H OG  1 
ATOM   1567  N  N   . ASN A 1 228 ? 14.261  51.341  51.671 1   68.87  ? 210 ASN H N   1 
ATOM   1568  C  CA  . ASN A 1 228 ? 12.832  51.577  51.319 1   73.79  ? 210 ASN H CA  1 
ATOM   1569  C  C   . ASN A 1 228 ? 12.525  53.084  51.383 1   71.28  ? 210 ASN H C   1 
ATOM   1570  O  O   . ASN A 1 228 ? 11.539  53.47   52.043 1   70.83  ? 210 ASN H O   1 
ATOM   1571  C  CB  . ASN A 1 228 ? 11.899  50.716  52.178 1   78.96  ? 210 ASN H CB  1 
ATOM   1572  C  CG  . ASN A 1 228 ? 10.588  50.387  51.488 1   85.07  ? 210 ASN H CG  1 
ATOM   1573  O  OD1 . ASN A 1 228 ? 10.118  51.139  50.632 1   88.11  ? 210 ASN H OD1 1 
ATOM   1574  N  ND2 . ASN A 1 228 ? 9.987   49.262  51.846 1   87.82  ? 210 ASN H ND2 1 
ATOM   1575  N  N   . THR A 1 229 ? 13.355  53.895  50.716 1   69.54  ? 211 THR H N   1 
ATOM   1576  C  CA  . THR A 1 229 ? 13.216  55.37   50.569 1   65.27  ? 211 THR H CA  1 
ATOM   1577  C  C   . THR A 1 229 ? 12.818  55.673  49.119 1   63.45  ? 211 THR H C   1 
ATOM   1578  O  O   . THR A 1 229 ? 13.636  55.413  48.216 1   60.73  ? 211 THR H O   1 
ATOM   1579  C  CB  . THR A 1 229 ? 14.511  56.087  50.979 1   65.11  ? 211 THR H CB  1 
ATOM   1580  O  OG1 . THR A 1 229 ? 14.856  55.693  52.307 1   65.11  ? 211 THR H OG1 1 
ATOM   1581  C  CG2 . THR A 1 229 ? 14.402  57.595  50.939 1   65.66  ? 211 THR H CG2 1 
ATOM   1582  N  N   . LYS A 1 230 ? 11.588  56.155  48.915 1   63.91  ? 212 LYS H N   1 
ATOM   1583  C  CA  . LYS A 1 230 ? 11.079  56.716  47.636 1   63.9   ? 212 LYS H CA  1 
ATOM   1584  C  C   . LYS A 1 230 ? 10.81   58.208  47.857 1   61.66  ? 212 LYS H C   1 
ATOM   1585  O  O   . LYS A 1 230 ? 9.846   58.526  48.579 1   64.52  ? 212 LYS H O   1 
ATOM   1586  C  CB  . LYS A 1 230 ? 9.797   56.007  47.181 1   67.12  ? 212 LYS H CB  1 
ATOM   1587  C  CG  . LYS A 1 230 ? 9.931   54.524  46.853 1   68.87  ? 212 LYS H CG  1 
ATOM   1588  C  CD  . LYS A 1 230 ? 8.596   53.854  46.559 1   71.61  ? 212 LYS H CD  1 
ATOM   1589  C  CE  . LYS A 1 230 ? 8.66    52.339  46.532 1   73.01  ? 212 LYS H CE  1 
ATOM   1590  N  NZ  . LYS A 1 230 ? 7.306   51.734  46.593 0   72.6   ? 212 LYS H NZ  1 
ATOM   1591  N  N   . VAL A 1 231 ? 11.652  59.081  47.295 1   59.07  ? 213 VAL H N   1 
ATOM   1592  C  CA  . VAL A 1 231 ? 11.505  60.565  47.371 1   54.83  ? 213 VAL H CA  1 
ATOM   1593  C  C   . VAL A 1 231 ? 11.234  61.083  45.96  1   52.75  ? 213 VAL H C   1 
ATOM   1594  O  O   . VAL A 1 231 ? 11.935  60.646  45.028 1   52.74  ? 213 VAL H O   1 
ATOM   1595  C  CB  . VAL A 1 231 ? 12.744  61.244  47.987 1   54.78  ? 213 VAL H CB  1 
ATOM   1596  C  CG1 . VAL A 1 231 ? 12.607  62.759  48.035 1   56.44  ? 213 VAL H CG1 1 
ATOM   1597  C  CG2 . VAL A 1 231 ? 13.045  60.714  49.378 1   56.1   ? 213 VAL H CG2 1 
ATOM   1598  N  N   . ASP A 1 232 ? 10.242  61.967  45.831 1   51.54  ? 214 ASP H N   1 
ATOM   1599  C  CA  . ASP A 1 232 ? 10.007  62.825  44.642 1   53.21  ? 214 ASP H CA  1 
ATOM   1600  C  C   . ASP A 1 232 ? 10.436  64.249  45.005 1   52.45  ? 214 ASP H C   1 
ATOM   1601  O  O   . ASP A 1 232 ? 10.042  64.716  46.092 1   53.8   ? 214 ASP H O   1 
ATOM   1602  C  CB  . ASP A 1 232 ? 8.54    62.795  44.209 1   55.35  ? 214 ASP H CB  1 
ATOM   1603  C  CG  . ASP A 1 232 ? 8.063   61.448  43.69  1   58.1   ? 214 ASP H CG  1 
ATOM   1604  O  OD1 . ASP A 1 232 ? 8.824   60.793  42.94  1   58.28  ? 214 ASP H OD1 1 
ATOM   1605  O  OD2 . ASP A 1 232 ? 6.93    61.069  44.031 1   61.77  ? 214 ASP H OD2 1 
ATOM   1606  N  N   . LYS A 1 233 ? 11.227  64.899  44.148 1   49.39  ? 215 LYS H N   1 
ATOM   1607  C  CA  . LYS A 1 233 ? 11.656  66.308  44.336 1   49.02  ? 215 LYS H CA  1 
ATOM   1608  C  C   . LYS A 1 233 ? 11.346  67.094  43.059 1   46.39  ? 215 LYS H C   1 
ATOM   1609  O  O   . LYS A 1 233 ? 11.935  66.777  42.01  1   44.45  ? 215 LYS H O   1 
ATOM   1610  C  CB  . LYS A 1 233 ? 13.14   66.383  44.707 1   51.01  ? 215 LYS H CB  1 
ATOM   1611  C  CG  . LYS A 1 233 ? 13.584  67.701  45.33  1   54.81  ? 215 LYS H CG  1 
ATOM   1612  C  CD  . LYS A 1 233 ? 13.662  67.686  46.848 1   58.3   ? 215 LYS H CD  1 
ATOM   1613  C  CE  . LYS A 1 233 ? 12.34   67.424  47.537 1   62.38  ? 215 LYS H CE  1 
ATOM   1614  N  NZ  . LYS A 1 233 ? 12.501  67.349  49.009 1   65.51  ? 215 LYS H NZ  1 
ATOM   1615  N  N   . LYS A 1 234 ? 10.439  68.069  43.157 1   46.2   ? 216 LYS H N   1 
ATOM   1616  C  CA  . LYS A 1 234 ? 10.186  69.072  42.093 1   47.79  ? 216 LYS H CA  1 
ATOM   1617  C  C   . LYS A 1 234 ? 11.43   69.96   41.979 1   45.06  ? 216 LYS H C   1 
ATOM   1618  O  O   . LYS A 1 234 ? 11.908  70.429  43.027 1   46.29  ? 216 LYS H O   1 
ATOM   1619  C  CB  . LYS A 1 234 ? 8.928   69.893  42.395 1   51.42  ? 216 LYS H CB  1 
ATOM   1620  C  CG  . LYS A 1 234 ? 8.524   70.852  41.281 1   55.93  ? 216 LYS H CG  1 
ATOM   1621  C  CD  . LYS A 1 234 ? 7.247   71.625  41.525 1   58.68  ? 216 LYS H CD  1 
ATOM   1622  C  CE  . LYS A 1 234 ? 6.883   72.491  40.335 1   61.62  ? 216 LYS H CE  1 
ATOM   1623  N  NZ  . LYS A 1 234 ? 6.039   73.645  40.719 1   64.28  ? 216 LYS H NZ  1 
ATOM   1624  N  N   . VAL A 1 235 ? 11.938  70.161  40.76  1   44.6   ? 217 VAL H N   1 
ATOM   1625  C  CA  . VAL A 1 235 ? 13.122  71.022  40.459 1   45     ? 217 VAL H CA  1 
ATOM   1626  C  C   . VAL A 1 235 ? 12.617  72.288  39.756 1   46.16  ? 217 VAL H C   1 
ATOM   1627  O  O   . VAL A 1 235 ? 12.381  72.241  38.532 1   45.89  ? 217 VAL H O   1 
ATOM   1628  C  CB  . VAL A 1 235 ? 14.175  70.264  39.627 1   43.75  ? 217 VAL H CB  1 
ATOM   1629  C  CG1 . VAL A 1 235 ? 15.487  71.029  39.523 1   43.3   ? 217 VAL H CG1 1 
ATOM   1630  C  CG2 . VAL A 1 235 ? 14.422  68.875  40.187 1   44.59  ? 217 VAL H CG2 1 
ATOM   1631  N  N   . GLU A 1 236 ? 12.402  73.357  40.525 1   49.09  ? 218 GLU H N   1 
ATOM   1632  C  CA  . GLU A 1 236 ? 11.918  74.672  40.027 1   53.27  ? 218 GLU H CA  1 
ATOM   1633  C  C   . GLU A 1 236 ? 13.122  75.548  39.696 1   55.38  ? 218 GLU H C   1 
ATOM   1634  O  O   . GLU A 1 236 ? 14.22   75.293  40.186 1   55.71  ? 218 GLU H O   1 
ATOM   1635  C  CB  . GLU A 1 236 ? 11.045  75.355  41.083 1   56.23  ? 218 GLU H CB  1 
ATOM   1636  C  CG  . GLU A 1 236 ? 9.749   74.618  41.372 1   59.84  ? 218 GLU H CG  1 
ATOM   1637  C  CD  . GLU A 1 236 ? 8.827   75.301  42.371 1   63.12  ? 218 GLU H CD  1 
ATOM   1638  O  OE1 . GLU A 1 236 ? 8.672   76.539  42.297 1   67.27  ? 218 GLU H OE1 1 
ATOM   1639  O  OE2 . GLU A 1 236 ? 8.253   74.591  43.218 1   65.91  ? 218 GLU H OE2 1 
ATOM   1640  N  N   . PRO A 1 237 ? 12.961  76.622  38.885 1   59.12  ? 219 PRO H N   1 
ATOM   1641  C  CA  . PRO A 1 237 ? 14.002  77.642  38.749 1   60.45  ? 219 PRO H CA  1 
ATOM   1642  C  C   . PRO A 1 237 ? 14.259  78.395  40.063 1   61.42  ? 219 PRO H C   1 
ATOM   1643  O  O   . PRO A 1 237 ? 13.527  78.202  41.015 1   58.06  ? 219 PRO H O   1 
ATOM   1644  C  CB  . PRO A 1 237 ? 13.457  78.593  37.674 1   60.36  ? 219 PRO H CB  1 
ATOM   1645  C  CG  . PRO A 1 237 ? 11.961  78.387  37.734 1   61.4   ? 219 PRO H CG  1 
ATOM   1646  C  CD  . PRO A 1 237 ? 11.788  76.916  38.046 1   60.03  ? 219 PRO H CD  1 
ATOM   1647  N  N   . LYS A 1 238 ? 15.274  79.259  40.053 1   68.44  ? 220 LYS H N   1 
ATOM   1648  C  CA  . LYS A 1 238 ? 15.844  79.929  41.254 1   72.62  ? 220 LYS H CA  1 
ATOM   1649  C  C   . LYS A 1 238 ? 14.912  81.077  41.675 1   77.67  ? 220 LYS H C   1 
ATOM   1650  O  O   . LYS A 1 238 ? 14.207  81.616  40.8   1   76.15  ? 220 LYS H O   1 
ATOM   1651  C  CB  . LYS A 1 238 ? 17.266  80.421  40.954 1   74.96  ? 220 LYS H CB  1 
ATOM   1652  C  CG  . LYS A 1 238 ? 18.093  79.526  40.037 1   78.21  ? 220 LYS H CG  1 
ATOM   1653  C  CD  . LYS A 1 238 ? 19.589  79.737  40.143 1   82.39  ? 220 LYS H CD  1 
ATOM   1654  C  CE  . LYS A 1 238 ? 20.228  78.956  41.272 1   83.24  ? 220 LYS H CE  1 
ATOM   1655  N  NZ  . LYS A 1 238 ? 21.69   78.831  41.074 1   85.35  ? 220 LYS H NZ  1 
ATOM   1656  N  N   . SER A 1 239 ? 14.911  81.439  42.964 1   85.17  ? 221 SER H N   1 
ATOM   1657  C  CA  . SER A 1 239 ? 14.089  82.536  43.552 1   88.86  ? 221 SER H CA  1 
ATOM   1658  C  C   . SER A 1 239 ? 14.529  83.908  43.014 1   92.13  ? 221 SER H C   1 
ATOM   1659  O  O   . SER A 1 239 ? 13.698  84.835  43.04  1   95.16  ? 221 SER H O   1 
ATOM   1660  C  CB  . SER A 1 239 ? 14.127  82.51   45.062 1   90.64  ? 221 SER H CB  1 
ATOM   1661  O  OG  . SER A 1 239 ? 13.405  81.396  45.568 1   90.99  ? 221 SER H OG  1 
ATOM   1662  N  N   . CYS A 1 240 ? 15.78   84.034  42.553 1   96.82  ? 222 CYS H N   1 
ATOM   1663  C  CA  . CYS A 1 240 ? 16.337  85.249  41.891 1   102.04 ? 222 CYS H CA  1 
ATOM   1664  C  C   . CYS A 1 240 ? 15.907  85.337  40.413 1   103.79 ? 222 CYS H C   1 
ATOM   1665  O  O   . CYS A 1 240 ? 16.139  86.405  39.807 1   104.88 ? 222 CYS H O   1 
ATOM   1666  C  CB  . CYS A 1 240 ? 17.861  85.292  42.013 1   103.52 ? 222 CYS H CB  1 
ATOM   1667  S  SG  . CYS A 1 240 ? 18.696  83.717  41.67  1   103.53 ? 222 CYS H SG  1 
ATOM   1668  N  N   . ASP A 1 241 ? 15.285  84.287  39.856 1   106.42 ? 223 ASP H N   1 
ATOM   1669  C  CA  . ASP A 1 241 ? 14.978  84.144  38.404 1   108.32 ? 223 ASP H CA  1 
ATOM   1670  C  C   . ASP A 1 241 ? 13.675  84.878  38.053 1   108.34 ? 223 ASP H C   1 
ATOM   1671  O  O   . ASP A 1 241 ? 12.686  84.736  38.805 1   102.18 ? 223 ASP H O   1 
ATOM   1672  C  CB  . ASP A 1 241 ? 14.876  82.665  38.011 1   109.38 ? 223 ASP H CB  1 
ATOM   1673  C  CG  . ASP A 1 241 ? 15.013  82.369  36.525 1   107.73 ? 223 ASP H CG  1 
ATOM   1674  O  OD1 . ASP A 1 241 ? 14.81   83.291  35.71  1   107.55 ? 223 ASP H OD1 1 
ATOM   1675  O  OD2 . ASP A 1 241 ? 15.313  81.205  36.196 1   106.51 ? 223 ASP H OD2 1 
ATOM   1676  N  N   . LYS A 1 242 ? 13.696  85.63   36.945 1   111.44 ? 224 LYS H N   1 
ATOM   1677  C  CA  . LYS A 1 242 ? 12.508  86.117  36.19  1   113.08 ? 224 LYS H CA  1 
ATOM   1678  C  C   . LYS A 1 242 ? 12.589  85.545  34.767 1   116.1  ? 224 LYS H C   1 
ATOM   1679  O  O   . LYS A 1 242 ? 13.668  85.679  34.148 1   112.82 ? 224 LYS H O   1 
ATOM   1680  C  CB  . LYS A 1 242 ? 12.457  87.649  36.193 1   112.13 ? 224 LYS H CB  1 
ATOM   1681  C  CG  . LYS A 1 242 ? 11.943  88.278  37.482 1   111.13 ? 224 LYS H CG  1 
ATOM   1682  C  CD  . LYS A 1 242 ? 11.946  89.788  37.472 0   116.3  ? 224 LYS H CD  1 
ATOM   1683  C  CE  . LYS A 1 242 ? 11.514  90.39   38.793 0   116.25 ? 224 LYS H CE  1 
ATOM   1684  N  NZ  . LYS A 1 242 ? 11.539  91.872  38.754 0   116.2  ? 224 LYS H NZ  1 
ATOM   1685  N  N   . THR A 1 243 ? 11.495  84.94   34.279 1   121.42 ? 225 THR H N   1 
ATOM   1686  C  CA  . THR A 1 243 ? 11.43   84.124  33.029 1   124.5  ? 225 THR H CA  1 
ATOM   1687  C  C   . THR A 1 243 ? 11.899  84.963  31.832 1   119.69 ? 225 THR H C   1 
ATOM   1688  O  O   . THR A 1 243 ? 13.061  84.9    31.431 1   107.22 ? 225 THR H O   1 
ATOM   1689  C  CB  . THR A 1 243 ? 10.022  83.567  32.756 1   128.97 ? 225 THR H CB  1 
ATOM   1690  O  OG1 . THR A 1 243 ? 9.11    84.657  32.607 1   136.78 ? 225 THR H OG1 1 
ATOM   1691  C  CG2 . THR A 1 243 ? 9.503   82.637  33.833 1   129.91 ? 225 THR H CG2 1 
ATOM   1692  N  N   . SER B 2 21  ? 36.142  26.018  37.726 1   92.28  ? 2   SER L N   1 
ATOM   1693  C  CA  . SER B 2 21  ? 37.169  26.829  36.981 1   89.73  ? 2   SER L CA  1 
ATOM   1694  C  C   . SER B 2 21  ? 36.472  27.909  36.135 1   85.6   ? 2   SER L C   1 
ATOM   1695  O  O   . SER B 2 21  ? 35.303  28.242  36.444 1   85.42  ? 2   SER L O   1 
ATOM   1696  C  CB  . SER B 2 21  ? 38.076  25.932  36.153 1   87.88  ? 2   SER L CB  1 
ATOM   1697  O  OG  . SER B 2 21  ? 37.454  25.552  34.934 1   86.89  ? 2   SER L OG  1 
ATOM   1698  N  N   . VAL B 2 22  ? 37.175  28.462  35.137 1   77.66  ? 3   VAL L N   1 
ATOM   1699  C  CA  . VAL B 2 22  ? 36.68   29.514  34.196 1   69.8   ? 3   VAL L CA  1 
ATOM   1700  C  C   . VAL B 2 22  ? 37.247  29.2    32.803 1   63.11  ? 3   VAL L C   1 
ATOM   1701  O  O   . VAL B 2 22  ? 38.449  28.882  32.73  1   64.68  ? 3   VAL L O   1 
ATOM   1702  C  CB  . VAL B 2 22  ? 37.093  30.914  34.704 1   69.8   ? 3   VAL L CB  1 
ATOM   1703  C  CG1 . VAL B 2 22  ? 36.917  32.012  33.665 1   70.37  ? 3   VAL L CG1 1 
ATOM   1704  C  CG2 . VAL B 2 22  ? 36.357  31.287  35.983 1   70.33  ? 3   VAL L CG2 1 
ATOM   1705  N  N   . LEU B 2 23  ? 36.427  29.284  31.746 1   56.46  ? 4   LEU L N   1 
ATOM   1706  C  CA  . LEU B 2 23  ? 36.89   29.173  30.328 1   51.19  ? 4   LEU L CA  1 
ATOM   1707  C  C   . LEU B 2 23  ? 37.838  30.343  30.047 1   48.33  ? 4   LEU L C   1 
ATOM   1708  O  O   . LEU B 2 23  ? 37.52   31.466  30.473 1   47.21  ? 4   LEU L O   1 
ATOM   1709  C  CB  . LEU B 2 23  ? 35.712  29.2    29.346 1   48.29  ? 4   LEU L CB  1 
ATOM   1710  C  CG  . LEU B 2 23  ? 34.624  28.145  29.536 1   47.64  ? 4   LEU L CG  1 
ATOM   1711  C  CD1 . LEU B 2 23  ? 33.469  28.388  28.577 1   46.48  ? 4   LEU L CD1 1 
ATOM   1712  C  CD2 . LEU B 2 23  ? 35.181  26.74   29.347 1   49.58  ? 4   LEU L CD2 1 
ATOM   1713  N  N   . THR B 2 24  ? 38.964  30.095  29.378 1   47.45  ? 5   THR L N   1 
ATOM   1714  C  CA  . THR B 2 24  ? 40.043  31.104  29.196 1   47.57  ? 5   THR L CA  1 
ATOM   1715  C  C   . THR B 2 24  ? 39.738  31.942  27.951 1   45.07  ? 5   THR L C   1 
ATOM   1716  O  O   . THR B 2 24  ? 39.77   31.375  26.841 1   47.3   ? 5   THR L O   1 
ATOM   1717  C  CB  . THR B 2 24  ? 41.429  30.451  29.166 1   47.76  ? 5   THR L CB  1 
ATOM   1718  O  OG1 . THR B 2 24  ? 41.515  29.564  30.282 1   48.51  ? 5   THR L OG1 1 
ATOM   1719  C  CG2 . THR B 2 24  ? 42.552  31.463  29.243 1   48.4   ? 5   THR L CG2 1 
ATOM   1720  N  N   . GLN B 2 25  ? 39.425  33.227  28.157 1   41.7   ? 6   GLN L N   1 
ATOM   1721  C  CA  . GLN B 2 25  ? 39.275  34.269  27.107 1   41.6   ? 6   GLN L CA  1 
ATOM   1722  C  C   . GLN B 2 25  ? 40.434  35.256  27.214 1   38.8   ? 6   GLN L C   1 
ATOM   1723  O  O   . GLN B 2 25  ? 40.973  35.452  28.299 1   37.66  ? 6   GLN L O   1 
ATOM   1724  C  CB  . GLN B 2 25  ? 37.985  35.069  27.296 1   43.46  ? 6   GLN L CB  1 
ATOM   1725  C  CG  . GLN B 2 25  ? 36.711  34.346  26.89  1   45.29  ? 6   GLN L CG  1 
ATOM   1726  C  CD  . GLN B 2 25  ? 35.489  35.202  27.127 1   46.73  ? 6   GLN L CD  1 
ATOM   1727  O  OE1 . GLN B 2 25  ? 34.579  34.821  27.861 1   47.96  ? 6   GLN L OE1 1 
ATOM   1728  N  NE2 . GLN B 2 25  ? 35.459  36.38   26.52  1   46.06  ? 6   GLN L NE2 1 
ATOM   1729  N  N   . PRO B 2 26  ? 40.818  35.961  26.125 1   37.84  ? 7   PRO L N   1 
ATOM   1730  C  CA  . PRO B 2 26  ? 41.795  37.042  26.232 1   39.38  ? 7   PRO L CA  1 
ATOM   1731  C  C   . PRO B 2 26  ? 41.171  38.202  27.001 1   40.68  ? 7   PRO L C   1 
ATOM   1732  O  O   . PRO B 2 26  ? 40.063  38.615  26.673 1   41.51  ? 7   PRO L O   1 
ATOM   1733  C  CB  . PRO B 2 26  ? 42.089  37.425  24.775 1   38.08  ? 7   PRO L CB  1 
ATOM   1734  C  CG  . PRO B 2 26  ? 40.832  37.032  24.034 1   39.02  ? 7   PRO L CG  1 
ATOM   1735  C  CD  . PRO B 2 26  ? 40.321  35.796  24.751 1   38.52  ? 7   PRO L CD  1 
ATOM   1736  N  N   . PRO B 2 27  ? 41.834  38.766  28.038 1   44.06  ? 8   PRO L N   1 
ATOM   1737  C  CA  . PRO B 2 27  ? 41.227  39.835  28.835 1   45.57  ? 8   PRO L CA  1 
ATOM   1738  C  C   . PRO B 2 27  ? 40.874  41.081  28.004 1   46.98  ? 8   PRO L C   1 
ATOM   1739  O  O   . PRO B 2 27  ? 39.985  41.812  28.407 1   52.36  ? 8   PRO L O   1 
ATOM   1740  C  CB  . PRO B 2 27  ? 42.271  40.159  29.919 1   44.43  ? 8   PRO L CB  1 
ATOM   1741  C  CG  . PRO B 2 27  ? 43.573  39.595  29.386 1   44.91  ? 8   PRO L CG  1 
ATOM   1742  C  CD  . PRO B 2 27  ? 43.189  38.427  28.501 1   44.86  ? 8   PRO L CD  1 
ATOM   1743  N  N   . SER B 2 28  ? 41.544  41.28   26.867 1   46.7   ? 9   SER L N   1 
ATOM   1744  C  CA  . SER B 2 28  ? 41.385  42.475  26.002 1   47.11  ? 9   SER L CA  1 
ATOM   1745  C  C   . SER B 2 28  ? 41.7    42.124  24.544 1   45.84  ? 9   SER L C   1 
ATOM   1746  O  O   . SER B 2 28  ? 42.687  41.397  24.331 1   48.83  ? 9   SER L O   1 
ATOM   1747  C  CB  . SER B 2 28  ? 42.275  43.579  26.495 1   47.54  ? 9   SER L CB  1 
ATOM   1748  O  OG  . SER B 2 28  ? 42.296  44.655  25.573 1   52.57  ? 9   SER L OG  1 
ATOM   1749  N  N   . VAL B 2 29  ? 40.873  42.611  23.609 1   43.01  ? 10  VAL L N   1 
ATOM   1750  C  CA  A VAL B 2 29  ? 41.135  42.579  22.135 0.5 43.15  ? 10  VAL L CA  1 
ATOM   1751  C  CA  B VAL B 2 29  ? 41.113  42.57   22.135 0.5 42.31  ? 10  VAL L CA  1 
ATOM   1752  C  C   . VAL B 2 29  ? 40.821  43.968  21.571 1   42.63  ? 10  VAL L C   1 
ATOM   1753  O  O   . VAL B 2 29  ? 39.834  44.576  22.022 1   40.12  ? 10  VAL L O   1 
ATOM   1754  C  CB  A VAL B 2 29  ? 40.33   41.489  21.396 0.5 43.87  ? 10  VAL L CB  1 
ATOM   1755  C  CB  B VAL B 2 29  ? 40.239  41.484  21.477 0.5 41.94  ? 10  VAL L CB  1 
ATOM   1756  C  CG1 A VAL B 2 29  ? 40.642  40.09   21.904 0.5 44.16  ? 10  VAL L CG1 1 
ATOM   1757  C  CG1 B VAL B 2 29  ? 40.249  41.569  19.965 0.5 40.9   ? 10  VAL L CG1 1 
ATOM   1758  C  CG2 A VAL B 2 29  ? 38.83   41.741  21.437 0.5 44.68  ? 10  VAL L CG2 1 
ATOM   1759  C  CG2 B VAL B 2 29  ? 40.632  40.083  21.92  0.5 42.13  ? 10  VAL L CG2 1 
ATOM   1760  N  N   . SER B 2 30  ? 41.639  44.442  20.626 1   43.47  ? 11  SER L N   1 
ATOM   1761  C  CA  . SER B 2 30  ? 41.478  45.771  19.974 1   43.17  ? 11  SER L CA  1 
ATOM   1762  C  C   . SER B 2 30  ? 41.447  45.616  18.451 1   41.5   ? 11  SER L C   1 
ATOM   1763  O  O   . SER B 2 30  ? 41.983  44.613  17.933 1   40.62  ? 11  SER L O   1 
ATOM   1764  C  CB  . SER B 2 30  ? 42.534  46.755  20.422 1   44.81  ? 11  SER L CB  1 
ATOM   1765  O  OG  . SER B 2 30  ? 43.846  46.274  20.175 1   46.76  ? 11  SER L OG  1 
ATOM   1766  N  N   . GLY B 2 31  ? 40.821  46.578  17.774 1   41.64  ? 12  GLY L N   1 
ATOM   1767  C  CA  . GLY B 2 31  ? 40.602  46.552  16.317 1   42.66  ? 12  GLY L CA  1 
ATOM   1768  C  C   . GLY B 2 31  ? 40.341  47.932  15.746 1   42.67  ? 12  GLY L C   1 
ATOM   1769  O  O   . GLY B 2 31  ? 39.873  48.806  16.495 1   42.14  ? 12  GLY L O   1 
ATOM   1770  N  N   . ALA B 2 32  ? 40.663  48.118  14.465 1   44.65  ? 13  ALA L N   1 
ATOM   1771  C  CA  . ALA B 2 32  ? 40.39   49.342  13.679 1   47     ? 13  ALA L CA  1 
ATOM   1772  C  C   . ALA B 2 32  ? 39.005  49.221  13.048 1   46.28  ? 13  ALA L C   1 
ATOM   1773  O  O   . ALA B 2 32  ? 38.563  48.109  12.761 1   47.76  ? 13  ALA L O   1 
ATOM   1774  C  CB  . ALA B 2 32  ? 41.464  49.531  12.634 1   47.71  ? 13  ALA L CB  1 
ATOM   1775  N  N   . PRO B 2 33  ? 38.275  50.339  12.814 1   44.24  ? 14  PRO L N   1 
ATOM   1776  C  CA  . PRO B 2 33  ? 36.97   50.281  12.151 1   44.97  ? 14  PRO L CA  1 
ATOM   1777  C  C   . PRO B 2 33  ? 37.022  49.572  10.788 1   45.18  ? 14  PRO L C   1 
ATOM   1778  O  O   . PRO B 2 33  ? 37.958  49.795  10.046 1   46.87  ? 14  PRO L O   1 
ATOM   1779  C  CB  . PRO B 2 33  ? 36.563  51.753  11.973 1   44.17  ? 14  PRO L CB  1 
ATOM   1780  C  CG  . PRO B 2 33  ? 37.339  52.485  13.048 1   43.82  ? 14  PRO L CG  1 
ATOM   1781  C  CD  . PRO B 2 33  ? 38.634  51.711  13.203 1   43.83  ? 14  PRO L CD  1 
ATOM   1782  N  N   . GLY B 2 34  ? 36.035  48.714  10.52  1   44.54  ? 15  GLY L N   1 
ATOM   1783  C  CA  . GLY B 2 34  ? 35.877  47.993  9.245  1   44.45  ? 15  GLY L CA  1 
ATOM   1784  C  C   . GLY B 2 34  ? 36.685  46.705  9.184  1   46.2   ? 15  GLY L C   1 
ATOM   1785  O  O   . GLY B 2 34  ? 36.536  45.986  8.172  1   48.71  ? 15  GLY L O   1 
ATOM   1786  N  N   . GLN B 2 35  ? 37.502  46.403  10.202 1   45.63  ? 16  GLN L N   1 
ATOM   1787  C  CA  . GLN B 2 35  ? 38.396  45.214  10.201 1   47.94  ? 16  GLN L CA  1 
ATOM   1788  C  C   . GLN B 2 35  ? 37.645  44.025  10.809 1   48.3   ? 16  GLN L C   1 
ATOM   1789  O  O   . GLN B 2 35  ? 36.592  44.246  11.446 1   50.02  ? 16  GLN L O   1 
ATOM   1790  C  CB  . GLN B 2 35  ? 39.725  45.531  10.897 1   52.06  ? 16  GLN L CB  1 
ATOM   1791  C  CG  . GLN B 2 35  ? 39.883  45.017  12.325 1   53.56  ? 16  GLN L CG  1 
ATOM   1792  C  CD  . GLN B 2 35  ? 41.311  45.174  12.795 1   53.31  ? 16  GLN L CD  1 
ATOM   1793  O  OE1 . GLN B 2 35  ? 41.901  46.248  12.68  1   54.23  ? 16  GLN L OE1 1 
ATOM   1794  N  NE2 . GLN B 2 35  ? 41.886  44.108  13.33  1   52.02  ? 16  GLN L NE2 1 
ATOM   1795  N  N   . ARG B 2 36  ? 38.166  42.814  10.578 1   45.26  ? 17  ARG L N   1 
ATOM   1796  C  CA  . ARG B 2 36  ? 37.706  41.55   11.205 1   43.36  ? 17  ARG L CA  1 
ATOM   1797  C  C   . ARG B 2 36  ? 38.522  41.33   12.479 1   44.74  ? 17  ARG L C   1 
ATOM   1798  O  O   . ARG B 2 36  ? 39.757  41.491  12.426 1   45.77  ? 17  ARG L O   1 
ATOM   1799  C  CB  . ARG B 2 36  ? 37.853  40.364  10.247 1   42.03  ? 17  ARG L CB  1 
ATOM   1800  C  CG  . ARG B 2 36  ? 37.362  39.037  10.808 1   42.27  ? 17  ARG L CG  1 
ATOM   1801  C  CD  . ARG B 2 36  ? 37.365  37.941  9.759  1   42.99  ? 17  ARG L CD  1 
ATOM   1802  N  NE  . ARG B 2 36  ? 37.073  36.612  10.291 1   43.71  ? 17  ARG L NE  1 
ATOM   1803  C  CZ  . ARG B 2 36  ? 37.907  35.863  11.023 1   44.68  ? 17  ARG L CZ  1 
ATOM   1804  N  NH1 . ARG B 2 36  ? 39.111  36.303  11.352 1   45.58  ? 17  ARG L NH1 1 
ATOM   1805  N  NH2 . ARG B 2 36  ? 37.527  34.666  11.443 1   44.85  ? 17  ARG L NH2 1 
ATOM   1806  N  N   . VAL B 2 37  ? 37.848  40.972  13.572 1   45.09  ? 18  VAL L N   1 
ATOM   1807  C  CA  . VAL B 2 37  ? 38.468  40.692  14.9   1   45.56  ? 18  VAL L CA  1 
ATOM   1808  C  C   . VAL B 2 37  ? 37.917  39.356  15.402 1   45.81  ? 18  VAL L C   1 
ATOM   1809  O  O   . VAL B 2 37  ? 36.781  39.02   15.009 1   48.57  ? 18  VAL L O   1 
ATOM   1810  C  CB  . VAL B 2 37  ? 38.189  41.852  15.873 1   47.82  ? 18  VAL L CB  1 
ATOM   1811  C  CG1 . VAL B 2 37  ? 36.735  41.931  16.314 1   46.88  ? 18  VAL L CG1 1 
ATOM   1812  C  CG2 . VAL B 2 37  ? 39.097  41.793  17.075 1   50.63  ? 18  VAL L CG2 1 
ATOM   1813  N  N   . THR B 2 38  ? 38.684  38.622  16.214 1   43.85  ? 19  THR L N   1 
ATOM   1814  C  CA  . THR B 2 38  ? 38.261  37.321  16.802 1   43.85  ? 19  THR L CA  1 
ATOM   1815  C  C   . THR B 2 38  ? 38.516  37.317  18.311 1   43.82  ? 19  THR L C   1 
ATOM   1816  O  O   . THR B 2 38  ? 39.502  37.942  18.753 1   47.53  ? 19  THR L O   1 
ATOM   1817  C  CB  . THR B 2 38  ? 38.935  36.117  16.127 1   43.7   ? 19  THR L CB  1 
ATOM   1818  O  OG1 . THR B 2 38  ? 40.348  36.207  16.293 1   42.88  ? 19  THR L OG1 1 
ATOM   1819  C  CG2 . THR B 2 38  ? 38.601  36.009  14.656 1   43.92  ? 19  THR L CG2 1 
ATOM   1820  N  N   . ILE B 2 39  ? 37.637  36.639  19.054 1   43.24  ? 20  ILE L N   1 
ATOM   1821  C  CA  . ILE B 2 39  ? 37.743  36.423  20.526 1   43.23  ? 20  ILE L CA  1 
ATOM   1822  C  C   . ILE B 2 39  ? 37.701  34.91   20.769 1   42.44  ? 20  ILE L C   1 
ATOM   1823  O  O   . ILE B 2 39  ? 36.672  34.291  20.454 1   41.67  ? 20  ILE L O   1 
ATOM   1824  C  CB  . ILE B 2 39  ? 36.644  37.192  21.291 1   42.58  ? 20  ILE L CB  1 
ATOM   1825  C  CG1 . ILE B 2 39  ? 36.595  38.659  20.847 1   41.97  ? 20  ILE L CG1 1 
ATOM   1826  C  CG2 . ILE B 2 39  ? 36.846  37.045  22.795 1   43.13  ? 20  ILE L CG2 1 
ATOM   1827  C  CD1 . ILE B 2 39  ? 35.629  39.542  21.611 1   42.61  ? 20  ILE L CD1 1 
ATOM   1828  N  N   . SER B 2 40  ? 38.802  34.35   21.273 1   42.74  ? 21  SER L N   1 
ATOM   1829  C  CA  . SER B 2 40  ? 38.966  32.904  21.555 1   44.52  ? 21  SER L CA  1 
ATOM   1830  C  C   . SER B 2 40  ? 38.327  32.576  22.908 1   44.86  ? 21  SER L C   1 
ATOM   1831  O  O   . SER B 2 40  ? 38.148  33.497  23.724 1   42.33  ? 21  SER L O   1 
ATOM   1832  C  CB  . SER B 2 40  ? 40.416  32.494  21.518 1   44.63  ? 21  SER L CB  1 
ATOM   1833  O  OG  . SER B 2 40  ? 41.113  32.992  22.652 1   47.1   ? 21  SER L OG  1 
ATOM   1834  N  N   . CYS B 2 41  ? 38.001  31.3    23.11  1   46.34  ? 22  CYS L N   1 
ATOM   1835  C  CA  . CYS B 2 41  ? 37.396  30.74   24.342 1   48.05  ? 22  CYS L CA  1 
ATOM   1836  C  C   . CYS B 2 41  ? 37.91   29.306  24.505 1   48.6   ? 22  CYS L C   1 
ATOM   1837  O  O   . CYS B 2 41  ? 37.312  28.398  23.904 1   49.31  ? 22  CYS L O   1 
ATOM   1838  C  CB  . CYS B 2 41  ? 35.874  30.81   24.259 1   49.21  ? 22  CYS L CB  1 
ATOM   1839  S  SG  . CYS B 2 41  ? 35.028  30.201  25.742 1   53.42  ? 22  CYS L SG  1 
ATOM   1840  N  N   . ALA B 2 42  ? 39.012  29.126  25.238 1   48.29  ? 23  ALA L N   1 
ATOM   1841  C  CA  . ALA B 2 42  ? 39.677  27.818  25.442 1   48.74  ? 23  ALA L CA  1 
ATOM   1842  C  C   . ALA B 2 42  ? 38.98   27.095  26.592 1   48.66  ? 23  ALA L C   1 
ATOM   1843  O  O   . ALA B 2 42  ? 38.969  27.643  27.712 1   50.25  ? 23  ALA L O   1 
ATOM   1844  C  CB  . ALA B 2 42  ? 41.152  27.991  25.715 1   48.16  ? 23  ALA L CB  1 
ATOM   1845  N  N   . GLY B 2 43  ? 38.419  25.92   26.308 1   49.35  ? 24  GLY L N   1 
ATOM   1846  C  CA  . GLY B 2 43  ? 37.719  25.064  27.283 1   51.29  ? 24  GLY L CA  1 
ATOM   1847  C  C   . GLY B 2 43  ? 38.379  23.703  27.394 1   51.94  ? 24  GLY L C   1 
ATOM   1848  O  O   . GLY B 2 43  ? 39.621  23.652  27.344 1   51.11  ? 24  GLY L O   1 
ATOM   1849  N  N   . THR B 2 44  ? 37.573  22.645  27.535 1   53.68  ? 25  THR L N   1 
ATOM   1850  C  CA  . THR B 2 44  ? 38.008  21.258  27.849 1   54.83  ? 25  THR L CA  1 
ATOM   1851  C  C   . THR B 2 44  ? 37.109  20.239  27.134 1   57.87  ? 25  THR L C   1 
ATOM   1852  O  O   . THR B 2 44  ? 36.099  20.646  26.521 1   54.84  ? 25  THR L O   1 
ATOM   1853  C  CB  . THR B 2 44  ? 37.978  20.978  29.359 1   52.03  ? 25  THR L CB  1 
ATOM   1854  O  OG1 . THR B 2 44  ? 36.623  20.726  29.73  1   53.22  ? 25  THR L OG1 1 
ATOM   1855  C  CG2 . THR B 2 44  ? 38.526  22.101  30.212 1   51.58  ? 25  THR L CG2 1 
ATOM   1856  N  N   . SER B 2 45  ? 37.467  18.956  27.252 1   62.62  ? 26  SER L N   1 
ATOM   1857  C  CA  . SER B 2 45  ? 36.688  17.773  26.792 1   64.19  ? 26  SER L CA  1 
ATOM   1858  C  C   . SER B 2 45  ? 35.345  17.675  27.531 1   61     ? 26  SER L C   1 
ATOM   1859  O  O   . SER B 2 45  ? 34.402  17.125  26.941 1   59.49  ? 26  SER L O   1 
ATOM   1860  C  CB  . SER B 2 45  ? 37.491  16.509  26.97  1   67.38  ? 26  SER L CB  1 
ATOM   1861  O  OG  . SER B 2 45  ? 38.005  16.421  28.294 1   67.99  ? 26  SER L OG  1 
ATOM   1862  N  N   . SER B 2 46  ? 35.268  18.175  28.77  1   59.03  ? 27  SER L N   1 
ATOM   1863  C  CA  . SER B 2 46  ? 34.049  18.15   29.624 1   59.39  ? 27  SER L CA  1 
ATOM   1864  C  C   . SER B 2 46  ? 33.031  19.232  29.215 1   58.35  ? 27  SER L C   1 
ATOM   1865  O  O   . SER B 2 46  ? 31.864  19.091  29.636 1   58.74  ? 27  SER L O   1 
ATOM   1866  C  CB  . SER B 2 46  ? 34.416  18.267  31.087 1   59.81  ? 27  SER L CB  1 
ATOM   1867  O  OG  . SER B 2 46  ? 34.852  19.582  31.406 1   61.85  ? 27  SER L OG  1 
ATOM   1868  N  N   . ASP B 2 47  ? 33.427  20.264  28.449 1   55.44  ? 28  ASP L N   1 
ATOM   1869  C  CA  . ASP B 2 47  ? 32.546  21.414  28.088 1   52.75  ? 28  ASP L CA  1 
ATOM   1870  C  C   . ASP B 2 47  ? 32.515  21.605  26.563 1   52.53  ? 28  ASP L C   1 
ATOM   1871  O  O   . ASP B 2 47  ? 31.618  21.004  25.941 1   54.55  ? 28  ASP L O   1 
ATOM   1872  C  CB  . ASP B 2 47  ? 32.894  22.68   28.881 1   51.42  ? 28  ASP L CB  1 
ATOM   1873  C  CG  . ASP B 2 47  ? 34.377  22.979  29.028 1   51.41  ? 28  ASP L CG  1 
ATOM   1874  O  OD1 . ASP B 2 47  ? 34.99   23.368  28.016 1   50.93  ? 28  ASP L OD1 1 
ATOM   1875  O  OD2 . ASP B 2 47  ? 34.904  22.831  30.152 1   50.33  ? 28  ASP L OD2 1 
ATOM   1876  N  N   . ILE B 2 48  ? 33.422  22.406  25.985 1   49.8   ? 29  ILE L N   1 
ATOM   1877  C  CA  . ILE B 2 48  ? 33.412  22.795  24.539 1   49.68  ? 29  ILE L CA  1 
ATOM   1878  C  C   . ILE B 2 48  ? 33.785  21.57   23.684 1   51.33  ? 29  ILE L C   1 
ATOM   1879  O  O   . ILE B 2 48  ? 33.195  21.413  22.595 1   50.74  ? 29  ILE L O   1 
ATOM   1880  C  CB  . ILE B 2 48  ? 34.338  24.01   24.281 1   49.06  ? 29  ILE L CB  1 
ATOM   1881  C  CG1 . ILE B 2 48  ? 33.889  25.229  25.096 1   49.29  ? 29  ILE L CG1 1 
ATOM   1882  C  CG2 . ILE B 2 48  ? 34.446  24.324  22.79  1   46.92  ? 29  ILE L CG2 1 
ATOM   1883  C  CD1 . ILE B 2 48  ? 34.631  26.52   24.799 1   48.88  ? 29  ILE L CD1 1 
ATOM   1884  N  N   . GLY B 2 49  ? 34.727  20.743  24.151 1   54.18  ? 30  GLY L N   1 
ATOM   1885  C  CA  . GLY B 2 49  ? 35.195  19.525  23.459 1   58.77  ? 30  GLY L CA  1 
ATOM   1886  C  C   . GLY B 2 49  ? 34.105  18.469  23.323 1   62.45  ? 30  GLY L C   1 
ATOM   1887  O  O   . GLY B 2 49  ? 33.584  18.011  24.365 1   59.35  ? 30  GLY L O   1 
ATOM   1888  N  N   . GLY B 2 50  ? 33.766  18.1    22.082 1   66.54  ? 31  GLY L N   1 
ATOM   1889  C  CA  . GLY B 2 50  ? 32.783  17.047  21.754 1   69.58  ? 31  GLY L CA  1 
ATOM   1890  C  C   . GLY B 2 50  ? 31.349  17.423  22.112 1   70.06  ? 31  GLY L C   1 
ATOM   1891  O  O   . GLY B 2 50  ? 30.536  16.495  22.283 1   71.47  ? 31  GLY L O   1 
ATOM   1892  N  N   . ARG B 2 51  ? 31.041  18.722  22.218 1   69.12  ? 32  ARG L N   1 
ATOM   1893  C  CA  . ARG B 2 51  ? 29.663  19.264  22.386 1   67.83  ? 32  ARG L CA  1 
ATOM   1894  C  C   . ARG B 2 51  ? 29.542  20.576  21.606 1   60.07  ? 32  ARG L C   1 
ATOM   1895  O  O   . ARG B 2 51  ? 30.584  21.115  21.189 1   59.02  ? 32  ARG L O   1 
ATOM   1896  C  CB  . ARG B 2 51  ? 29.335  19.481  23.866 1   71.93  ? 32  ARG L CB  1 
ATOM   1897  C  CG  . ARG B 2 51  ? 28.661  18.295  24.539 1   75.48  ? 32  ARG L CG  1 
ATOM   1898  C  CD  . ARG B 2 51  ? 28.843  18.321  26.042 1   80.33  ? 32  ARG L CD  1 
ATOM   1899  N  NE  . ARG B 2 51  ? 28.595  17.031  26.672 1   84.25  ? 32  ARG L NE  1 
ATOM   1900  C  CZ  . ARG B 2 51  ? 28.904  16.726  27.933 1   90.44  ? 32  ARG L CZ  1 
ATOM   1901  N  NH1 . ARG B 2 51  ? 29.477  17.621  28.725 1   95.96  ? 32  ARG L NH1 1 
ATOM   1902  N  NH2 . ARG B 2 51  ? 28.642  15.518  28.405 1   91.56  ? 32  ARG L NH2 1 
ATOM   1903  N  N   . THR B 2 52  ? 28.312  21.061  21.434 1   54.1   ? 33  THR L N   1 
ATOM   1904  C  CA  . THR B 2 52  ? 27.974  22.253  20.615 1   50.64  ? 33  THR L CA  1 
ATOM   1905  C  C   . THR B 2 52  ? 27.163  23.261  21.439 1   48.78  ? 33  THR L C   1 
ATOM   1906  O  O   . THR B 2 52  ? 26.498  24.108  20.818 1   51.06  ? 33  THR L O   1 
ATOM   1907  C  CB  . THR B 2 52  ? 27.218  21.826  19.352 1   49.75  ? 33  THR L CB  1 
ATOM   1908  O  OG1 . THR B 2 52  ? 25.979  21.256  19.776 1   49.76  ? 33  THR L OG1 1 
ATOM   1909  C  CG2 . THR B 2 52  ? 28.004  20.85   18.503 1   49.89  ? 33  THR L CG2 1 
ATOM   1910  N  N   . TYR B 2 53  ? 27.242  23.217  22.773 1   46.62  ? 34  TYR L N   1 
ATOM   1911  C  CA  . TYR B 2 53  ? 26.413  24.058  23.679 1   44.52  ? 34  TYR L CA  1 
ATOM   1912  C  C   . TYR B 2 53  ? 27.227  25.27   24.141 1   42.37  ? 34  TYR L C   1 
ATOM   1913  O  O   . TYR B 2 53  ? 27.208  25.592  25.337 1   43.16  ? 34  TYR L O   1 
ATOM   1914  C  CB  . TYR B 2 53  ? 25.874  23.216  24.839 1   44.52  ? 34  TYR L CB  1 
ATOM   1915  C  CG  . TYR B 2 53  ? 24.918  22.13   24.421 1   43.85  ? 34  TYR L CG  1 
ATOM   1916  C  CD1 . TYR B 2 53  ? 23.784  22.427  23.68  1   43.48  ? 34  TYR L CD1 1 
ATOM   1917  C  CD2 . TYR B 2 53  ? 25.133  20.808  24.778 1   43.83  ? 34  TYR L CD2 1 
ATOM   1918  C  CE1 . TYR B 2 53  ? 22.896  21.437  23.292 1   44.19  ? 34  TYR L CE1 1 
ATOM   1919  C  CE2 . TYR B 2 53  ? 24.252  19.806  24.404 1   42.91  ? 34  TYR L CE2 1 
ATOM   1920  C  CZ  . TYR B 2 53  ? 23.13   20.121  23.655 1   43.86  ? 34  TYR L CZ  1 
ATOM   1921  O  OH  . TYR B 2 53  ? 22.251  19.146  23.281 1   42.95  ? 34  TYR L OH  1 
ATOM   1922  N  N   . VAL B 2 54  ? 27.902  25.93   23.198 1   41.44  ? 35  VAL L N   1 
ATOM   1923  C  CA  . VAL B 2 54  ? 28.71   27.161  23.423 1   40.38  ? 35  VAL L CA  1 
ATOM   1924  C  C   . VAL B 2 54  ? 27.84   28.353  23.023 1   38.12  ? 35  VAL L C   1 
ATOM   1925  O  O   . VAL B 2 54  ? 27.255  28.313  21.927 1   40.77  ? 35  VAL L O   1 
ATOM   1926  C  CB  . VAL B 2 54  ? 30.026  27.118  22.623 1   42.03  ? 35  VAL L CB  1 
ATOM   1927  C  CG1 . VAL B 2 54  ? 30.863  28.38   22.803 1   41.73  ? 35  VAL L CG1 1 
ATOM   1928  C  CG2 . VAL B 2 54  ? 30.838  25.89   22.994 1   43.52  ? 35  VAL L CG2 1 
ATOM   1929  N  N   . SER B 2 55  ? 27.746  29.359  23.887 1   36.2   ? 36  SER L N   1 
ATOM   1930  C  CA  . SER B 2 55  ? 26.977  30.605  23.638 1   37.94  ? 36  SER L CA  1 
ATOM   1931  C  C   . SER B 2 55  ? 27.876  31.821  23.876 1   36.72  ? 36  SER L C   1 
ATOM   1932  O  O   . SER B 2 55  ? 28.833  31.706  24.663 1   38.5   ? 36  SER L O   1 
ATOM   1933  C  CB  . SER B 2 55  ? 25.732  30.651  24.487 1   38.28  ? 36  SER L CB  1 
ATOM   1934  O  OG  . SER B 2 55  ? 26.058  30.544  25.865 1   38.49  ? 36  SER L OG  1 
ATOM   1935  N  N   . TRP B 2 56  ? 27.582  32.931  23.201 1   36.05  ? 37  TRP L N   1 
ATOM   1936  C  CA  . TRP B 2 56  ? 28.305  34.223  23.337 1   37.61  ? 37  TRP L CA  1 
ATOM   1937  C  C   . TRP B 2 56  ? 27.32   35.313  23.757 1   37.01  ? 37  TRP L C   1 
ATOM   1938  O  O   . TRP B 2 56  ? 26.201  35.347  23.196 1   37.84  ? 37  TRP L O   1 
ATOM   1939  C  CB  . TRP B 2 56  ? 29.016  34.583  22.028 1   39.54  ? 37  TRP L CB  1 
ATOM   1940  C  CG  . TRP B 2 56  ? 30.22   33.738  21.751 1   41.01  ? 37  TRP L CG  1 
ATOM   1941  C  CD1 . TRP B 2 56  ? 30.258  32.556  21.072 1   42.14  ? 37  TRP L CD1 1 
ATOM   1942  C  CD2 . TRP B 2 56  ? 31.567  34.001  22.175 1   42.41  ? 37  TRP L CD2 1 
ATOM   1943  N  NE1 . TRP B 2 56  ? 31.537  32.072  21.032 1   42.93  ? 37  TRP L NE1 1 
ATOM   1944  C  CE2 . TRP B 2 56  ? 32.363  32.936  21.699 1   43.34  ? 37  TRP L CE2 1 
ATOM   1945  C  CE3 . TRP B 2 56  ? 32.184  35.039  22.883 1   44.38  ? 37  TRP L CE3 1 
ATOM   1946  C  CZ2 . TRP B 2 56  ? 33.742  32.887  21.907 1   43.79  ? 37  TRP L CZ2 1 
ATOM   1947  C  CZ3 . TRP B 2 56  ? 33.547  34.985  23.095 1   45.19  ? 37  TRP L CZ3 1 
ATOM   1948  C  CH2 . TRP B 2 56  ? 34.313  33.924  22.61  1   43.61  ? 37  TRP L CH2 1 
ATOM   1949  N  N   . TYR B 2 57  ? 27.731  36.174  24.688 1   37.05  ? 38  TYR L N   1 
ATOM   1950  C  CA  . TYR B 2 57  ? 26.918  37.296  25.223 1   37.12  ? 38  TYR L CA  1 
ATOM   1951  C  C   . TYR B 2 57  ? 27.665  38.609  24.995 1   38.04  ? 38  TYR L C   1 
ATOM   1952  O  O   . TYR B 2 57  ? 28.907  38.612  25.055 1   38.14  ? 38  TYR L O   1 
ATOM   1953  C  CB  . TYR B 2 57  ? 26.586  37.057  26.698 1   37.08  ? 38  TYR L CB  1 
ATOM   1954  C  CG  . TYR B 2 57  ? 25.921  35.728  26.927 1   38.34  ? 38  TYR L CG  1 
ATOM   1955  C  CD1 . TYR B 2 57  ? 26.675  34.58   27.112 1   39.06  ? 38  TYR L CD1 1 
ATOM   1956  C  CD2 . TYR B 2 57  ? 24.543  35.597  26.878 1   39.56  ? 38  TYR L CD2 1 
ATOM   1957  C  CE1 . TYR B 2 57  ? 26.08   33.342  27.284 1   38.72  ? 38  TYR L CE1 1 
ATOM   1958  C  CE2 . TYR B 2 57  ? 23.933  34.363  27.048 1   40.76  ? 38  TYR L CE2 1 
ATOM   1959  C  CZ  . TYR B 2 57  ? 24.702  33.229  27.254 1   39.08  ? 38  TYR L CZ  1 
ATOM   1960  O  OH  . TYR B 2 57  ? 24.111  32.012  27.438 1   40.02  ? 38  TYR L OH  1 
ATOM   1961  N  N   . GLN B 2 58  ? 26.916  39.676  24.717 1   39.33  ? 39  GLN L N   1 
ATOM   1962  C  CA  . GLN B 2 58  ? 27.414  41.075  24.683 1   40.53  ? 39  GLN L CA  1 
ATOM   1963  C  C   . GLN B 2 58  ? 26.895  41.786  25.934 1   39.64  ? 39  GLN L C   1 
ATOM   1964  O  O   . GLN B 2 58  ? 25.681  41.704  26.181 1   38.6   ? 39  GLN L O   1 
ATOM   1965  C  CB  . GLN B 2 58  ? 26.939  41.786  23.416 1   41.71  ? 39  GLN L CB  1 
ATOM   1966  C  CG  . GLN B 2 58  ? 27.472  43.204  23.27  1   42.64  ? 39  GLN L CG  1 
ATOM   1967  C  CD  . GLN B 2 58  ? 26.899  43.883  22.05  1   44.37  ? 39  GLN L CD  1 
ATOM   1968  O  OE1 . GLN B 2 58  ? 25.699  44.134  21.971 1   45.72  ? 39  GLN L OE1 1 
ATOM   1969  N  NE2 . GLN B 2 58  ? 27.75   44.189  21.081 1   46.43  ? 39  GLN L NE2 1 
ATOM   1970  N  N   . GLN B 2 59  ? 27.786  42.442  26.684 1   40.23  ? 40  GLN L N   1 
ATOM   1971  C  CA  . GLN B 2 59  ? 27.437  43.322  27.83  1   41.64  ? 40  GLN L CA  1 
ATOM   1972  C  C   . GLN B 2 59  ? 27.953  44.737  27.548 1   42.82  ? 40  GLN L C   1 
ATOM   1973  O  O   . GLN B 2 59  ? 29.177  44.961  27.647 1   42.67  ? 40  GLN L O   1 
ATOM   1974  C  CB  . GLN B 2 59  ? 28.001  42.779  29.145 1   41.26  ? 40  GLN L CB  1 
ATOM   1975  C  CG  . GLN B 2 59  ? 27.554  43.597  30.351 1   41.14  ? 40  GLN L CG  1 
ATOM   1976  C  CD  . GLN B 2 59  ? 27.73   42.88   31.666 1   39.49  ? 40  GLN L CD  1 
ATOM   1977  O  OE1 . GLN B 2 59  ? 28.702  42.16   31.873 1   41.04  ? 40  GLN L OE1 1 
ATOM   1978  N  NE2 . GLN B 2 59  ? 26.791  43.08   32.577 1   39.23  ? 40  GLN L NE2 1 
ATOM   1979  N  N   . LEU B 2 60  ? 27.045  45.653  27.205 1   44.37  ? 41  LEU L N   1 
ATOM   1980  C  CA  . LEU B 2 60  ? 27.313  47.116  27.162 1   45.04  ? 41  LEU L CA  1 
ATOM   1981  C  C   . LEU B 2 60  ? 27.392  47.609  28.605 1   47.86  ? 41  LEU L C   1 
ATOM   1982  O  O   . LEU B 2 60  ? 26.94   46.91   29.509 1   45     ? 41  LEU L O   1 
ATOM   1983  C  CB  . LEU B 2 60  ? 26.199  47.804  26.363 1   42.83  ? 41  LEU L CB  1 
ATOM   1984  C  CG  . LEU B 2 60  ? 26.121  47.409  24.888 1   41.25  ? 41  LEU L CG  1 
ATOM   1985  C  CD1 . LEU B 2 60  ? 24.786  47.801  24.28  1   39.69  ? 41  LEU L CD1 1 
ATOM   1986  C  CD2 . LEU B 2 60  ? 27.265  48.029  24.103 1   42.39  ? 41  LEU L CD2 1 
ATOM   1987  N  N   . PRO B 2 61  ? 27.999  48.787  28.886 1   55.99  ? 42  PRO L N   1 
ATOM   1988  C  CA  . PRO B 2 61  ? 28.11   49.281  30.262 1   57.14  ? 42  PRO L CA  1 
ATOM   1989  C  C   . PRO B 2 61  ? 26.746  49.518  30.933 1   56.39  ? 42  PRO L C   1 
ATOM   1990  O  O   . PRO B 2 61  ? 25.85   50.019  30.276 1   50.96  ? 42  PRO L O   1 
ATOM   1991  C  CB  . PRO B 2 61  ? 28.888  50.598  30.117 1   59.89  ? 42  PRO L CB  1 
ATOM   1992  C  CG  . PRO B 2 61  ? 28.638  51.014  28.685 1   60.93  ? 42  PRO L CG  1 
ATOM   1993  C  CD  . PRO B 2 61  ? 28.62   49.707  27.919 1   59.69  ? 42  PRO L CD  1 
ATOM   1994  N  N   . GLY B 2 62  ? 26.623  49.094  32.199 1   58.79  ? 43  GLY L N   1 
ATOM   1995  C  CA  . GLY B 2 62  ? 25.438  49.276  33.062 1   59.59  ? 43  GLY L CA  1 
ATOM   1996  C  C   . GLY B 2 62  ? 24.179  48.598  32.537 1   61.17  ? 43  GLY L C   1 
ATOM   1997  O  O   . GLY B 2 62  ? 23.083  49.022  32.953 1   68.16  ? 43  GLY L O   1 
ATOM   1998  N  N   . THR B 2 63  ? 24.307  47.577  31.681 1   58.16  ? 44  THR L N   1 
ATOM   1999  C  CA  . THR B 2 63  ? 23.173  46.795  31.113 1   53.17  ? 44  THR L CA  1 
ATOM   2000  C  C   . THR B 2 63  ? 23.432  45.301  31.328 1   47.45  ? 44  THR L C   1 
ATOM   2001  O  O   . THR B 2 63  ? 24.603  44.911  31.443 1   44.13  ? 44  THR L O   1 
ATOM   2002  C  CB  . THR B 2 63  ? 22.941  47.125  29.631 1   54.95  ? 44  THR L CB  1 
ATOM   2003  O  OG1 . THR B 2 63  ? 24.19   47.097  28.943 1   55.78  ? 44  THR L OG1 1 
ATOM   2004  C  CG2 . THR B 2 63  ? 22.294  48.476  29.423 1   55.57  ? 44  THR L CG2 1 
ATOM   2005  N  N   . ALA B 2 64  ? 22.361  44.509  31.393 1   46.2   ? 45  ALA L N   1 
ATOM   2006  C  CA  . ALA B 2 64  ? 22.396  43.032  31.501 1   44     ? 45  ALA L CA  1 
ATOM   2007  C  C   . ALA B 2 64  ? 23.02   42.443  30.235 1   42.52  ? 45  ALA L C   1 
ATOM   2008  O  O   . ALA B 2 64  ? 22.937  43.056  29.17  1   39.72  ? 45  ALA L O   1 
ATOM   2009  C  CB  . ALA B 2 64  ? 21.003  42.496  31.727 1   43.28  ? 45  ALA L CB  1 
ATOM   2010  N  N   . PRO B 2 65  ? 23.654  41.245  30.298 1   41.29  ? 46  PRO L N   1 
ATOM   2011  C  CA  . PRO B 2 65  ? 24.15   40.569  29.1   1   40.31  ? 46  PRO L CA  1 
ATOM   2012  C  C   . PRO B 2 65  ? 23.032  40.265  28.094 1   40.26  ? 46  PRO L C   1 
ATOM   2013  O  O   . PRO B 2 65  ? 21.901  40.077  28.508 1   41     ? 46  PRO L O   1 
ATOM   2014  C  CB  . PRO B 2 65  ? 24.749  39.25   29.616 1   40.68  ? 46  PRO L CB  1 
ATOM   2015  C  CG  . PRO B 2 65  ? 25.03   39.509  31.078 1   40.95  ? 46  PRO L CG  1 
ATOM   2016  C  CD  . PRO B 2 65  ? 23.945  40.471  31.518 1   42     ? 46  PRO L CD  1 
ATOM   2017  N  N   . LYS B 2 66  ? 23.385  40.254  26.809 1   40.9   ? 47  LYS L N   1 
ATOM   2018  C  CA  . LYS B 2 66  ? 22.497  39.937  25.663 1   41.76  ? 47  LYS L CA  1 
ATOM   2019  C  C   . LYS B 2 66  ? 23.125  38.768  24.896 1   42.3   ? 47  LYS L C   1 
ATOM   2020  O  O   . LYS B 2 66  ? 24.298  38.889  24.517 1   45.05  ? 47  LYS L O   1 
ATOM   2021  C  CB  . LYS B 2 66  ? 22.343  41.175  24.774 1   43.18  ? 47  LYS L CB  1 
ATOM   2022  C  CG  . LYS B 2 66  ? 21.474  41.001  23.529 1   46.89  ? 47  LYS L CG  1 
ATOM   2023  C  CD  . LYS B 2 66  ? 21.881  41.883  22.355 1   46.57  ? 47  LYS L CD  1 
ATOM   2024  C  CE  . LYS B 2 66  ? 20.999  41.713  21.15  0   46.04  ? 47  LYS L CE  1 
ATOM   2025  N  NZ  . LYS B 2 66  ? 21.433  42.579  20.029 0   46.06  ? 47  LYS L NZ  1 
ATOM   2026  N  N   . LEU B 2 67  ? 22.379  37.683  24.689 1   41.42  ? 48  LEU L N   1 
ATOM   2027  C  CA  . LEU B 2 67  ? 22.809  36.524  23.866 1   41.36  ? 48  LEU L CA  1 
ATOM   2028  C  C   . LEU B 2 67  ? 23.03   37.004  22.428 1   40.44  ? 48  LEU L C   1 
ATOM   2029  O  O   . LEU B 2 67  ? 22.082  37.567  21.86  1   38.42  ? 48  LEU L O   1 
ATOM   2030  C  CB  . LEU B 2 67  ? 21.736  35.429  23.919 1   42.03  ? 48  LEU L CB  1 
ATOM   2031  C  CG  . LEU B 2 67  ? 22.005  34.19   23.064 1   42.92  ? 48  LEU L CG  1 
ATOM   2032  C  CD1 . LEU B 2 67  ? 23.202  33.416  23.584 1   43.05  ? 48  LEU L CD1 1 
ATOM   2033  C  CD2 . LEU B 2 67  ? 20.785  33.291  23.021 1   44.95  ? 48  LEU L CD2 1 
ATOM   2034  N  N   . LEU B 2 68  ? 24.23   36.779  21.878 1   40.1   ? 49  LEU L N   1 
ATOM   2035  C  CA  . LEU B 2 68  ? 24.561  37.013  20.448 1   41.58  ? 49  LEU L CA  1 
ATOM   2036  C  C   . LEU B 2 68  ? 24.43   35.694  19.686 1   41.22  ? 49  LEU L C   1 
ATOM   2037  O  O   . LEU B 2 68  ? 23.652  35.648  18.713 1   42.65  ? 49  LEU L O   1 
ATOM   2038  C  CB  . LEU B 2 68  ? 25.991  37.547  20.311 1   43.55  ? 49  LEU L CB  1 
ATOM   2039  C  CG  . LEU B 2 68  ? 26.28   38.934  20.882 1   45.1   ? 49  LEU L CG  1 
ATOM   2040  C  CD1 . LEU B 2 68  ? 27.685  39.354  20.491 1   47.53  ? 49  LEU L CD1 1 
ATOM   2041  C  CD2 . LEU B 2 68  ? 25.278  39.981  20.414 1   45.49  ? 49  LEU L CD2 1 
ATOM   2042  N  N   . ILE B 2 69  ? 25.185  34.682  20.123 1   40.79  ? 50  ILE L N   1 
ATOM   2043  C  CA  . ILE B 2 69  ? 25.335  33.356  19.452 1   39.95  ? 50  ILE L CA  1 
ATOM   2044  C  C   . ILE B 2 69  ? 24.99   32.261  20.461 1   40.29  ? 50  ILE L C   1 
ATOM   2045  O  O   . ILE B 2 69  ? 25.463  32.35   21.605 1   39.66  ? 50  ILE L O   1 
ATOM   2046  C  CB  . ILE B 2 69  ? 26.766  33.147  18.916 1   39.97  ? 50  ILE L CB  1 
ATOM   2047  C  CG1 . ILE B 2 69  ? 27.28   34.336  18.093 1   39.12  ? 50  ILE L CG1 1 
ATOM   2048  C  CG2 . ILE B 2 69  ? 26.865  31.835  18.148 1   39.64  ? 50  ILE L CG2 1 
ATOM   2049  C  CD1 . ILE B 2 69  ? 26.631  34.501  16.747 1   38.66  ? 50  ILE L CD1 1 
ATOM   2050  N  N   . TYR B 2 70  ? 24.23   31.254  20.029 1   42.2   ? 51  TYR L N   1 
ATOM   2051  C  CA  . TYR B 2 70  ? 24.029  29.972  20.753 1   43.85  ? 51  TYR L CA  1 
ATOM   2052  C  C   . TYR B 2 70  ? 24.326  28.82   19.786 1   44.37  ? 51  TYR L C   1 
ATOM   2053  O  O   . TYR B 2 70  ? 24.365  29.056  18.569 1   43.3   ? 51  TYR L O   1 
ATOM   2054  C  CB  . TYR B 2 70  ? 22.626  29.91   21.369 1   42.44  ? 51  TYR L CB  1 
ATOM   2055  C  CG  . TYR B 2 70  ? 21.475  29.9    20.395 1   41.18  ? 51  TYR L CG  1 
ATOM   2056  C  CD1 . TYR B 2 70  ? 20.935  31.08   19.907 1   40.4   ? 51  TYR L CD1 1 
ATOM   2057  C  CD2 . TYR B 2 70  ? 20.901  28.705  19.98  1   42.05  ? 51  TYR L CD2 1 
ATOM   2058  C  CE1 . TYR B 2 70  ? 19.869  31.073  19.019 1   41.69  ? 51  TYR L CE1 1 
ATOM   2059  C  CE2 . TYR B 2 70  ? 19.839  28.68   19.087 1   41.1   ? 51  TYR L CE2 1 
ATOM   2060  C  CZ  . TYR B 2 70  ? 19.316  29.87   18.612 1   41.54  ? 51  TYR L CZ  1 
ATOM   2061  O  OH  . TYR B 2 70  ? 18.272  29.849  17.735 1   42.89  ? 51  TYR L OH  1 
ATOM   2062  N  N   . LYS B 2 71  ? 24.537  27.616  20.324 1   47.61  ? 52  LYS L N   1 
ATOM   2063  C  CA  . LYS B 2 71  ? 24.77   26.367  19.544 1   50.45  ? 52  LYS L CA  1 
ATOM   2064  C  C   . LYS B 2 71  ? 26.006  26.552  18.648 1   48.74  ? 52  LYS L C   1 
ATOM   2065  O  O   . LYS B 2 71  ? 25.947  26.17   17.46  1   49.18  ? 52  LYS L O   1 
ATOM   2066  C  CB  . LYS B 2 71  ? 23.499  25.992  18.767 1   53.75  ? 52  LYS L CB  1 
ATOM   2067  C  CG  . LYS B 2 71  ? 22.735  24.789  19.303 1   55.49  ? 52  LYS L CG  1 
ATOM   2068  C  CD  . LYS B 2 71  ? 23.437  23.474  19.085 1   55.11  ? 52  LYS L CD  1 
ATOM   2069  C  CE  . LYS B 2 71  ? 22.51   22.283  19.186 1   55.33  ? 52  LYS L CE  1 
ATOM   2070  N  NZ  . LYS B 2 71  ? 23.174  21.044  18.714 1   56.72  ? 52  LYS L NZ  1 
ATOM   2071  N  N   . VAL B 2 72  ? 27.068  27.165  19.184 1   45.8   ? 53  VAL L N   1 
ATOM   2072  C  CA  . VAL B 2 72  ? 28.355  27.451  18.48  1   45.69  ? 53  VAL L CA  1 
ATOM   2073  C  C   . VAL B 2 72  ? 28.155  28.542  17.42  1   46.33  ? 53  VAL L C   1 
ATOM   2074  O  O   . VAL B 2 72  ? 28.911  29.528  17.471 1   48.03  ? 53  VAL L O   1 
ATOM   2075  C  CB  . VAL B 2 72  ? 28.967  26.187  17.841 1   45.58  ? 53  VAL L CB  1 
ATOM   2076  C  CG1 . VAL B 2 72  ? 30.305  26.481  17.182 1   46.56  ? 53  VAL L CG1 1 
ATOM   2077  C  CG2 . VAL B 2 72  ? 29.11   25.049  18.839 1   44.43  ? 53  VAL L CG2 1 
ATOM   2078  N  N   . THR B 2 73  ? 27.242  28.332  16.462 1   46.39  ? 54  THR L N   1 
ATOM   2079  C  CA  . THR B 2 73  ? 27.135  29.087  15.182 1   45.56  ? 54  THR L CA  1 
ATOM   2080  C  C   . THR B 2 73  ? 25.849  29.917  15.087 1   46.27  ? 54  THR L C   1 
ATOM   2081  O  O   . THR B 2 73  ? 25.852  30.87   14.29  1   48.09  ? 54  THR L O   1 
ATOM   2082  C  CB  . THR B 2 73  ? 27.159  28.125  13.987 1   45.36  ? 54  THR L CB  1 
ATOM   2083  O  OG1 . THR B 2 73  ? 26.024  27.265  14.088 1   44.93  ? 54  THR L OG1 1 
ATOM   2084  C  CG2 . THR B 2 73  ? 28.42   27.292  13.92  1   45.13  ? 54  THR L CG2 1 
ATOM   2085  N  N   . ILE B 2 74  ? 24.78   29.556  15.808 1   47.82  ? 55  ILE L N   1 
ATOM   2086  C  CA  . ILE B 2 74  ? 23.409  30.104  15.562 1   47.66  ? 55  ILE L CA  1 
ATOM   2087  C  C   . ILE B 2 74  ? 23.315  31.509  16.169 1   47.81  ? 55  ILE L C   1 
ATOM   2088  O  O   . ILE B 2 74  ? 23.596  31.677  17.363 1   48.25  ? 55  ILE L O   1 
ATOM   2089  C  CB  . ILE B 2 74  ? 22.284  29.183  16.08  1   46.93  ? 55  ILE L CB  1 
ATOM   2090  C  CG1 . ILE B 2 74  ? 22.423  27.752  15.548 1   47.13  ? 55  ILE L CG1 1 
ATOM   2091  C  CG2 . ILE B 2 74  ? 20.927  29.787  15.736 1   46.63  ? 55  ILE L CG2 1 
ATOM   2092  C  CD1 . ILE B 2 74  ? 21.408  26.77   16.101 1   47.88  ? 55  ILE L CD1 1 
ATOM   2093  N  N   . ARG B 2 75  ? 22.863  32.461  15.362 1   48.56  ? 56  ARG L N   1 
ATOM   2094  C  CA  . ARG B 2 75  ? 22.827  33.903  15.689 1   49.01  ? 56  ARG L CA  1 
ATOM   2095  C  C   . ARG B 2 75  ? 21.441  34.231  16.247 1   50.32  ? 56  ARG L C   1 
ATOM   2096  O  O   . ARG B 2 75  ? 20.449  33.938  15.555 1   51.21  ? 56  ARG L O   1 
ATOM   2097  C  CB  . ARG B 2 75  ? 23.148  34.688  14.417 1   50.05  ? 56  ARG L CB  1 
ATOM   2098  C  CG  . ARG B 2 75  ? 23.917  35.975  14.649 1   51.71  ? 56  ARG L CG  1 
ATOM   2099  C  CD  . ARG B 2 75  ? 24.421  36.564  13.351 1   52.68  ? 56  ARG L CD  1 
ATOM   2100  N  NE  . ARG B 2 75  ? 23.382  36.595  12.324 1   53.28  ? 56  ARG L NE  1 
ATOM   2101  C  CZ  . ARG B 2 75  ? 23.303  35.8    11.252 1   53.34  ? 56  ARG L CZ  1 
ATOM   2102  N  NH1 . ARG B 2 75  ? 24.226  34.882  10.999 1   53.71  ? 56  ARG L NH1 1 
ATOM   2103  N  NH2 . ARG B 2 75  ? 22.288  35.942  10.415 1   53.21  ? 56  ARG L NH2 1 
ATOM   2104  N  N   . ALA B 2 76  ? 21.379  34.817  17.446 1   50.91  ? 57  ALA L N   1 
ATOM   2105  C  CA  . ALA B 2 76  ? 20.13   35.242  18.122 1   50.41  ? 57  ALA L CA  1 
ATOM   2106  C  C   . ALA B 2 76  ? 19.363  36.245  17.25  1   50.61  ? 57  ALA L C   1 
ATOM   2107  O  O   . ALA B 2 76  ? 19.962  36.819  16.318 1   50.1   ? 57  ALA L O   1 
ATOM   2108  C  CB  . ALA B 2 76  ? 20.454  35.835  19.468 1   51.18  ? 57  ALA L CB  1 
ATOM   2109  N  N   . SER B 2 77  ? 18.08   36.449  17.561 1   54.64  ? 58  SER L N   1 
ATOM   2110  C  CA  . SER B 2 77  ? 17.161  37.397  16.871 1   57.17  ? 58  SER L CA  1 
ATOM   2111  C  C   . SER B 2 77  ? 17.765  38.805  16.885 1   54.89  ? 58  SER L C   1 
ATOM   2112  O  O   . SER B 2 77  ? 18.222  39.234  17.961 1   52.35  ? 58  SER L O   1 
ATOM   2113  C  CB  . SER B 2 77  ? 15.789  37.397  17.505 1   58.56  ? 58  SER L CB  1 
ATOM   2114  O  OG  . SER B 2 77  ? 15.371  36.074  17.811 1   62.08  ? 58  SER L OG  1 
ATOM   2115  N  N   . GLY B 2 78  ? 17.8    39.473  15.728 1   55.83  ? 59  GLY L N   1 
ATOM   2116  C  CA  . GLY B 2 78  ? 18.239  40.877  15.591 1   58.46  ? 59  GLY L CA  1 
ATOM   2117  C  C   . GLY B 2 78  ? 19.744  41.021  15.396 1   59.37  ? 59  GLY L C   1 
ATOM   2118  O  O   . GLY B 2 78  ? 20.16   42.084  14.886 1   63.24  ? 59  GLY L O   1 
ATOM   2119  N  N   . VAL B 2 79  ? 20.536  40.006  15.764 1   55.6   ? 60  VAL L N   1 
ATOM   2120  C  CA  . VAL B 2 79  ? 22.027  40.063  15.768 1   56.11  ? 60  VAL L CA  1 
ATOM   2121  C  C   . VAL B 2 79  ? 22.506  40.025  14.317 1   55.36  ? 60  VAL L C   1 
ATOM   2122  O  O   . VAL B 2 79  ? 22.211  39.066  13.608 1   53.72  ? 60  VAL L O   1 
ATOM   2123  C  CB  . VAL B 2 79  ? 22.625  38.919  16.611 1   55.42  ? 60  VAL L CB  1 
ATOM   2124  C  CG1 . VAL B 2 79  ? 24.146  38.865  16.538 1   55.03  ? 60  VAL L CG1 1 
ATOM   2125  C  CG2 . VAL B 2 79  ? 22.178  39.01   18.061 1   56.57  ? 60  VAL L CG2 1 
ATOM   2126  N  N   . PRO B 2 80  ? 23.245  41.054  13.828 1   55.49  ? 61  PRO L N   1 
ATOM   2127  C  CA  . PRO B 2 80  ? 23.704  41.08   12.436 1   56     ? 61  PRO L CA  1 
ATOM   2128  C  C   . PRO B 2 80  ? 24.751  39.999  12.126 1   54.17  ? 61  PRO L C   1 
ATOM   2129  O  O   . PRO B 2 80  ? 25.52   39.66   13.004 1   51.51  ? 61  PRO L O   1 
ATOM   2130  C  CB  . PRO B 2 80  ? 24.312  42.481  12.257 1   56.13  ? 61  PRO L CB  1 
ATOM   2131  C  CG  . PRO B 2 80  ? 24.681  42.923  13.658 1   55.37  ? 61  PRO L CG  1 
ATOM   2132  C  CD  . PRO B 2 80  ? 23.679  42.249  14.574 1   55.69  ? 61  PRO L CD  1 
ATOM   2133  N  N   . ASP B 2 81  ? 24.765  39.522  10.877 1   56.47  ? 62  ASP L N   1 
ATOM   2134  C  CA  . ASP B 2 81  ? 25.651  38.428  10.378 1   59.08  ? 62  ASP L CA  1 
ATOM   2135  C  C   . ASP B 2 81  ? 27.132  38.842  10.407 1   56.82  ? 62  ASP L C   1 
ATOM   2136  O  O   . ASP B 2 81  ? 27.977  37.954  10.177 1   59.85  ? 62  ASP L O   1 
ATOM   2137  C  CB  . ASP B 2 81  ? 25.238  37.954  8.98   1   61.38  ? 62  ASP L CB  1 
ATOM   2138  C  CG  . ASP B 2 81  ? 25.166  39.044  7.924  1   64.51  ? 62  ASP L CG  1 
ATOM   2139  O  OD1 . ASP B 2 81  ? 25.078  40.233  8.303  1   67.15  ? 62  ASP L OD1 1 
ATOM   2140  O  OD2 . ASP B 2 81  ? 25.176  38.691  6.73   1   68.95  ? 62  ASP L OD2 1 
ATOM   2141  N  N   . ARG B 2 82  ? 27.442  40.119  10.672 1   54.39  ? 63  ARG L N   1 
ATOM   2142  C  CA  . ARG B 2 82  ? 28.8    40.597  11.063 1   52.75  ? 63  ARG L CA  1 
ATOM   2143  C  C   . ARG B 2 82  ? 29.358  39.697  12.172 1   50.64  ? 63  ARG L C   1 
ATOM   2144  O  O   . ARG B 2 82  ? 30.566  39.396  12.128 1   53.17  ? 63  ARG L O   1 
ATOM   2145  C  CB  . ARG B 2 82  ? 28.768  42.054  11.539 1   52.32  ? 63  ARG L CB  1 
ATOM   2146  C  CG  . ARG B 2 82  ? 28.387  43.052  10.454 1   53.19  ? 63  ARG L CG  1 
ATOM   2147  C  CD  . ARG B 2 82  ? 28.755  44.493  10.754 1   52.3   ? 63  ARG L CD  1 
ATOM   2148  N  NE  . ARG B 2 82  ? 28.143  45.031  11.968 1   50.07  ? 63  ARG L NE  1 
ATOM   2149  C  CZ  . ARG B 2 82  ? 28.74   45.177  13.157 1   48.57  ? 63  ARG L CZ  1 
ATOM   2150  N  NH1 . ARG B 2 82  ? 29.994  44.798  13.355 1   48.36  ? 63  ARG L NH1 1 
ATOM   2151  N  NH2 . ARG B 2 82  ? 28.059  45.702  14.164 1   48.52  ? 63  ARG L NH2 1 
ATOM   2152  N  N   . PHE B 2 83  ? 28.506  39.29   13.119 1   47.77  ? 64  PHE L N   1 
ATOM   2153  C  CA  . PHE B 2 83  ? 28.827  38.328  14.205 1   47.02  ? 64  PHE L CA  1 
ATOM   2154  C  C   . PHE B 2 83  ? 28.695  36.903  13.663 1   46.05  ? 64  PHE L C   1 
ATOM   2155  O  O   . PHE B 2 83  ? 27.665  36.594  13.042 1   47.71  ? 64  PHE L O   1 
ATOM   2156  C  CB  . PHE B 2 83  ? 27.919  38.553  15.416 1   48.23  ? 64  PHE L CB  1 
ATOM   2157  C  CG  . PHE B 2 83  ? 28.13   39.888  16.08  1   48.37  ? 64  PHE L CG  1 
ATOM   2158  C  CD1 . PHE B 2 83  ? 29.066  40.033  17.094 1   48.53  ? 64  PHE L CD1 1 
ATOM   2159  C  CD2 . PHE B 2 83  ? 27.423  41.008  15.665 1   48.04  ? 64  PHE L CD2 1 
ATOM   2160  C  CE1 . PHE B 2 83  ? 29.279  41.266  17.692 1   48.72  ? 64  PHE L CE1 1 
ATOM   2161  C  CE2 . PHE B 2 83  ? 27.636  42.241  16.265 1   49.28  ? 64  PHE L CE2 1 
ATOM   2162  C  CZ  . PHE B 2 83  ? 28.562  42.367  17.278 1   49.37  ? 64  PHE L CZ  1 
ATOM   2163  N  N   . SER B 2 84  ? 29.728  36.083  13.864 1   43.72  ? 65  SER L N   1 
ATOM   2164  C  CA  . SER B 2 84  ? 29.738  34.635  13.537 1   42.22  ? 65  SER L CA  1 
ATOM   2165  C  C   . SER B 2 84  ? 30.51   33.875  14.617 1   41.02  ? 65  SER L C   1 
ATOM   2166  O  O   . SER B 2 84  ? 31.436  34.46   15.223 1   39.01  ? 65  SER L O   1 
ATOM   2167  C  CB  . SER B 2 84  ? 30.295  34.371  12.155 1   42.21  ? 65  SER L CB  1 
ATOM   2168  O  OG  . SER B 2 84  ? 31.714  34.404  12.144 1   40.86  ? 65  SER L OG  1 
ATOM   2169  N  N   . GLY B 2 85  ? 30.119  32.621  14.842 1   39.86  ? 66  GLY L N   1 
ATOM   2170  C  CA  . GLY B 2 85  ? 30.715  31.727  15.846 1   39.28  ? 66  GLY L CA  1 
ATOM   2171  C  C   . GLY B 2 85  ? 31.257  30.475  15.193 1   39.02  ? 66  GLY L C   1 
ATOM   2172  O  O   . GLY B 2 85  ? 30.716  30.069  14.148 1   38.2   ? 66  GLY L O   1 
ATOM   2173  N  N   . SER B 2 86  ? 32.301  29.896  15.777 1   40.07  ? 67  SER L N   1 
ATOM   2174  C  CA  . SER B 2 86  ? 32.915  28.627  15.317 1   42.66  ? 67  SER L CA  1 
ATOM   2175  C  C   . SER B 2 86  ? 33.544  27.892  16.5   1   43.4   ? 67  SER L C   1 
ATOM   2176  O  O   . SER B 2 86  ? 33.728  28.505  17.57  1   43.37  ? 67  SER L O   1 
ATOM   2177  C  CB  . SER B 2 86  ? 33.923  28.865  14.211 1   43.59  ? 67  SER L CB  1 
ATOM   2178  O  OG  . SER B 2 86  ? 35.085  29.522  14.701 1   43.29  ? 67  SER L OG  1 
ATOM   2179  N  N   . LYS B 2 87  ? 33.865  26.621  16.271 1   47.56  ? 68  LYS L N   1 
ATOM   2180  C  CA  . LYS B 2 87  ? 34.444  25.676  17.256 1   49.77  ? 68  LYS L CA  1 
ATOM   2181  C  C   . LYS B 2 87  ? 35.565  24.91   16.553 1   49.15  ? 68  LYS L C   1 
ATOM   2182  O  O   . LYS B 2 87  ? 35.435  24.663  15.336 1   47.86  ? 68  LYS L O   1 
ATOM   2183  C  CB  . LYS B 2 87  ? 33.352  24.727  17.768 1   51.86  ? 68  LYS L CB  1 
ATOM   2184  C  CG  . LYS B 2 87  ? 33.762  23.761  18.872 1   53     ? 68  LYS L CG  1 
ATOM   2185  C  CD  . LYS B 2 87  ? 32.623  22.88   19.351 1   54.19  ? 68  LYS L CD  1 
ATOM   2186  C  CE  . LYS B 2 87  ? 32.659  21.473  18.794 1   55.12  ? 68  LYS L CE  1 
ATOM   2187  N  NZ  . LYS B 2 87  ? 33.505  20.589  19.628 1   56.54  ? 68  LYS L NZ  1 
ATOM   2188  N  N   . SER B 2 88  ? 36.623  24.577  17.291 1   48.98  ? 69  SER L N   1 
ATOM   2189  C  CA  . SER B 2 88  ? 37.689  23.637  16.867 1   49.93  ? 69  SER L CA  1 
ATOM   2190  C  C   . SER B 2 88  ? 38.235  22.935  18.113 1   49.72  ? 69  SER L C   1 
ATOM   2191  O  O   . SER B 2 88  ? 38.898  23.613  18.929 1   46.74  ? 69  SER L O   1 
ATOM   2192  C  CB  . SER B 2 88  ? 38.771  24.342  16.089 1   51.66  ? 69  SER L CB  1 
ATOM   2193  O  OG  . SER B 2 88  ? 39.718  23.41   15.586 1   51.63  ? 69  SER L OG  1 
ATOM   2194  N  N   . GLY B 2 89  ? 37.926  21.641  18.261 1   50.61  ? 70  GLY L N   1 
ATOM   2195  C  CA  . GLY B 2 89  ? 38.279  20.83   19.439 1   52.3   ? 70  GLY L CA  1 
ATOM   2196  C  C   . GLY B 2 89  ? 37.706  21.43   20.714 1   52.75  ? 70  GLY L C   1 
ATOM   2197  O  O   . GLY B 2 89  ? 36.465  21.524  20.812 1   51.91  ? 70  GLY L O   1 
ATOM   2198  N  N   . THR B 2 90  ? 38.58   21.87   21.624 1   51.39  ? 71  THR L N   1 
ATOM   2199  C  CA  . THR B 2 90  ? 38.248  22.289  23.011 1   52.06  ? 71  THR L CA  1 
ATOM   2200  C  C   . THR B 2 90  ? 38.31   23.819  23.14  1   54.34  ? 71  THR L C   1 
ATOM   2201  O  O   . THR B 2 90  ? 38.576  24.301  24.256 1   58.59  ? 71  THR L O   1 
ATOM   2202  C  CB  . THR B 2 90  ? 39.198  21.609  24.004 1   51.92  ? 71  THR L CB  1 
ATOM   2203  O  OG1 . THR B 2 90  ? 40.513  22.051  23.674 1   52.08  ? 71  THR L OG1 1 
ATOM   2204  C  CG2 . THR B 2 90  ? 39.137  20.098  23.959 1   52.54  ? 71  THR L CG2 1 
ATOM   2205  N  N   . SER B 2 91  ? 38.074  24.561  22.054 1   53.01  ? 72  SER L N   1 
ATOM   2206  C  CA  . SER B 2 91  ? 38.053  26.046  22.063 1   52.77  ? 72  SER L CA  1 
ATOM   2207  C  C   . SER B 2 91  ? 37.112  26.579  20.975 1   50.3   ? 72  SER L C   1 
ATOM   2208  O  O   . SER B 2 91  ? 37.031  25.958  19.887 1   48.66  ? 72  SER L O   1 
ATOM   2209  C  CB  . SER B 2 91  ? 39.446  26.622  21.946 1   54.77  ? 72  SER L CB  1 
ATOM   2210  O  OG  . SER B 2 91  ? 39.899  26.61   20.603 1   60.82  ? 72  SER L OG  1 
ATOM   2211  N  N   . ALA B 2 92  ? 36.409  27.673  21.287 1   46.39  ? 73  ALA L N   1 
ATOM   2212  C  CA  . ALA B 2 92  ? 35.454  28.366  20.395 1   45.14  ? 73  ALA L CA  1 
ATOM   2213  C  C   . ALA B 2 92  ? 35.94   29.797  20.143 1   44.59  ? 73  ALA L C   1 
ATOM   2214  O  O   . ALA B 2 92  ? 36.724  30.323  20.965 1   43     ? 73  ALA L O   1 
ATOM   2215  C  CB  . ALA B 2 92  ? 34.078  28.347  21.003 1   45.81  ? 73  ALA L CB  1 
ATOM   2216  N  N   . SER B 2 93  ? 35.496  30.387  19.032 1   43.51  ? 74  SER L N   1 
ATOM   2217  C  CA  . SER B 2 93  ? 35.86   31.757  18.593 1   45.49  ? 74  SER L CA  1 
ATOM   2218  C  C   . SER B 2 93  ? 34.6    32.493  18.149 1   44.27  ? 74  SER L C   1 
ATOM   2219  O  O   . SER B 2 93  ? 33.855  31.938  17.318 1   44.15  ? 74  SER L O   1 
ATOM   2220  C  CB  . SER B 2 93  ? 36.896  31.74   17.496 1   46.75  ? 74  SER L CB  1 
ATOM   2221  O  OG  . SER B 2 93  ? 38.19   31.513  18.035 1   49.83  ? 74  SER L OG  1 
ATOM   2222  N  N   . LEU B 2 94  ? 34.367  33.672  18.724 1   44.21  ? 75  LEU L N   1 
ATOM   2223  C  CA  . LEU B 2 94  ? 33.444  34.694  18.173 1   42.84  ? 75  LEU L CA  1 
ATOM   2224  C  C   . LEU B 2 94  ? 34.269  35.512  17.181 1   43.37  ? 75  LEU L C   1 
ATOM   2225  O  O   . LEU B 2 94  ? 35.421  35.844  17.517 1   42.61  ? 75  LEU L O   1 
ATOM   2226  C  CB  . LEU B 2 94  ? 32.884  35.556  19.308 1   42.65  ? 75  LEU L CB  1 
ATOM   2227  C  CG  . LEU B 2 94  ? 31.977  36.714  18.892 1   44.06  ? 75  LEU L CG  1 
ATOM   2228  C  CD1 . LEU B 2 94  ? 30.66   36.2    18.336 1   44.41  ? 75  LEU L CD1 1 
ATOM   2229  C  CD2 . LEU B 2 94  ? 31.729  37.656  20.061 1   44.75  ? 75  LEU L CD2 1 
ATOM   2230  N  N   . ALA B 2 95  ? 33.707  35.786  16.004 1   42.54  ? 76  ALA L N   1 
ATOM   2231  C  CA  . ALA B 2 95  ? 34.336  36.577  14.927 1   41.24  ? 76  ALA L CA  1 
ATOM   2232  C  C   . ALA B 2 95  ? 33.421  37.755  14.585 1   40.87  ? 76  ALA L C   1 
ATOM   2233  O  O   . ALA B 2 95  ? 32.227  37.517  14.319 1   40.08  ? 76  ALA L O   1 
ATOM   2234  C  CB  . ALA B 2 95  ? 34.588  35.69   13.733 1   41.65  ? 76  ALA L CB  1 
ATOM   2235  N  N   . ILE B 2 96  ? 33.964  38.975  14.6   1   41.17  ? 77  ILE L N   1 
ATOM   2236  C  CA  . ILE B 2 96  ? 33.237  40.226  14.237 1   43.49  ? 77  ILE L CA  1 
ATOM   2237  C  C   . ILE B 2 96  ? 33.955  40.85   13.034 1   46.32  ? 77  ILE L C   1 
ATOM   2238  O  O   . ILE B 2 96  ? 35.141  41.208  13.19  1   45.58  ? 77  ILE L O   1 
ATOM   2239  C  CB  . ILE B 2 96  ? 33.147  41.201  15.432 1   42.31  ? 77  ILE L CB  1 
ATOM   2240  C  CG1 . ILE B 2 96  ? 32.719  40.496  16.723 1   40.71  ? 77  ILE L CG1 1 
ATOM   2241  C  CG2 . ILE B 2 96  ? 32.234  42.376  15.094 1   43.25  ? 77  ILE L CG2 1 
ATOM   2242  C  CD1 . ILE B 2 96  ? 33.031  41.262  17.983 1   41.38  ? 77  ILE L CD1 1 
ATOM   2243  N  N   . THR B 2 97  ? 33.266  40.935  11.885 1   47.41  ? 78  THR L N   1 
ATOM   2244  C  CA  . THR B 2 97  ? 33.702  41.662  10.66  1   47.4   ? 78  THR L CA  1 
ATOM   2245  C  C   . THR B 2 97  ? 33.011  43.025  10.626 1   48.8   ? 78  THR L C   1 
ATOM   2246  O  O   . THR B 2 97  ? 32.066  43.227  11.417 1   51.73  ? 78  THR L O   1 
ATOM   2247  C  CB  . THR B 2 97  ? 33.402  40.896  9.362  1   47.2   ? 78  THR L CB  1 
ATOM   2248  O  OG1 . THR B 2 97  ? 32.018  41.037  9.036  1   47.62  ? 78  THR L OG1 1 
ATOM   2249  C  CG2 . THR B 2 97  ? 33.773  39.432  9.435  1   47.79  ? 78  THR L CG2 1 
ATOM   2250  N  N   . GLY B 2 98  ? 33.464  43.902  9.726  1   50.51  ? 79  GLY L N   1 
ATOM   2251  C  CA  . GLY B 2 98  ? 33.01   45.301  9.606  1   48.72  ? 79  GLY L CA  1 
ATOM   2252  C  C   . GLY B 2 98  ? 32.917  45.961  10.968 1   47.13  ? 79  GLY L C   1 
ATOM   2253  O  O   . GLY B 2 98  ? 31.835  46.49   11.282 1   49.93  ? 79  GLY L O   1 
ATOM   2254  N  N   . LEU B 2 99  ? 34      45.896  11.751 1   45.36  ? 80  LEU L N   1 
ATOM   2255  C  CA  . LEU B 2 99  ? 34.033  46.316  13.179 1   46.34  ? 80  LEU L CA  1 
ATOM   2256  C  C   . LEU B 2 99  ? 33.657  47.798  13.277 1   46.96  ? 80  LEU L C   1 
ATOM   2257  O  O   . LEU B 2 99  ? 34.153  48.588  12.453 1   46.9   ? 80  LEU L O   1 
ATOM   2258  C  CB  . LEU B 2 99  ? 35.426  46.046  13.759 1   47.26  ? 80  LEU L CB  1 
ATOM   2259  C  CG  . LEU B 2 99  ? 35.647  46.476  15.209 1   48.91  ? 80  LEU L CG  1 
ATOM   2260  C  CD1 . LEU B 2 99  ? 34.762  45.68   16.154 1   50.74  ? 80  LEU L CD1 1 
ATOM   2261  C  CD2 . LEU B 2 99  ? 37.106  46.32   15.6   1   48.32  ? 80  LEU L CD2 1 
ATOM   2262  N  N   . GLN B 2 100 ? 32.797  48.14   14.239 1   48.87  ? 81  GLN L N   1 
ATOM   2263  C  CA  . GLN B 2 100 ? 32.206  49.494  14.417 1   49.46  ? 81  GLN L CA  1 
ATOM   2264  C  C   . GLN B 2 100 ? 32.353  49.922  15.875 1   46.78  ? 81  GLN L C   1 
ATOM   2265  O  O   . GLN B 2 100 ? 32.383  49.034  16.741 1   46.27  ? 81  GLN L O   1 
ATOM   2266  C  CB  . GLN B 2 100 ? 30.723  49.487  14.046 1   54.41  ? 81  GLN L CB  1 
ATOM   2267  C  CG  . GLN B 2 100 ? 30.463  49.336  12.555 1   58.49  ? 81  GLN L CG  1 
ATOM   2268  C  CD  . GLN B 2 100 ? 29.081  48.793  12.278 1   64.2   ? 81  GLN L CD  1 
ATOM   2269  O  OE1 . GLN B 2 100 ? 28.108  49.163  12.937 1   64.94  ? 81  GLN L OE1 1 
ATOM   2270  N  NE2 . GLN B 2 100 ? 28.981  47.911  11.294 1   66.04  ? 81  GLN L NE2 1 
ATOM   2271  N  N   . ALA B 2 101 ? 32.389  51.233  16.123 1   46.58  ? 82  ALA L N   1 
ATOM   2272  C  CA  . ALA B 2 101 ? 32.543  51.851  17.462 1   46.8   ? 82  ALA L CA  1 
ATOM   2273  C  C   . ALA B 2 101 ? 31.486  51.297  18.433 1   45.97  ? 82  ALA L C   1 
ATOM   2274  O  O   . ALA B 2 101 ? 31.821  51.067  19.609 1   44.6   ? 82  ALA L O   1 
ATOM   2275  C  CB  . ALA B 2 101 ? 32.458  53.355  17.345 1   46.25  ? 82  ALA L CB  1 
ATOM   2276  N  N   . GLU B 2 102 ? 30.269  51.043  17.947 1   47.78  ? 83  GLU L N   1 
ATOM   2277  C  CA  . GLU B 2 102 ? 29.113  50.581  18.772 1   51.94  ? 83  GLU L CA  1 
ATOM   2278  C  C   . GLU B 2 102 ? 29.238  49.078  19.09  1   49.85  ? 83  GLU L C   1 
ATOM   2279  O  O   . GLU B 2 102 ? 28.368  48.582  19.826 1   53.94  ? 83  GLU L O   1 
ATOM   2280  C  CB  . GLU B 2 102 ? 27.752  50.951  18.152 1   56.53  ? 83  GLU L CB  1 
ATOM   2281  C  CG  . GLU B 2 102 ? 27.684  51.021  16.627 1   61.22  ? 83  GLU L CG  1 
ATOM   2282  C  CD  . GLU B 2 102 ? 28.061  52.373  16.029 1   63.82  ? 83  GLU L CD  1 
ATOM   2283  O  OE1 . GLU B 2 102 ? 29.026  52.423  15.232 1   62.42  ? 83  GLU L OE1 1 
ATOM   2284  O  OE2 . GLU B 2 102 ? 27.397  53.378  16.37  1   66.07  ? 83  GLU L OE2 1 
ATOM   2285  N  N   . ASP B 2 103 ? 30.285  48.39   18.611 1   45.9   ? 84  ASP L N   1 
ATOM   2286  C  CA  . ASP B 2 103 ? 30.654  47.015  19.047 1   43.97  ? 84  ASP L CA  1 
ATOM   2287  C  C   . ASP B 2 103 ? 31.517  47.042  20.315 1   42.82  ? 84  ASP L C   1 
ATOM   2288  O  O   . ASP B 2 103 ? 31.855  45.946  20.797 1   42.56  ? 84  ASP L O   1 
ATOM   2289  C  CB  . ASP B 2 103 ? 31.414  46.254  17.959 1   44.54  ? 84  ASP L CB  1 
ATOM   2290  C  CG  . ASP B 2 103 ? 30.663  46.11   16.65  1   46.3   ? 84  ASP L CG  1 
ATOM   2291  O  OD1 . ASP B 2 103 ? 29.413  46.194  16.671 1   46.98  ? 84  ASP L OD1 1 
ATOM   2292  O  OD2 . ASP B 2 103 ? 31.335  45.884  15.62  1   47.8   ? 84  ASP L OD2 1 
ATOM   2293  N  N   . GLU B 2 104 ? 31.896  48.216  20.832 1   43.16  ? 85  GLU L N   1 
ATOM   2294  C  CA  . GLU B 2 104 ? 32.714  48.319  22.073 1   43.18  ? 85  GLU L CA  1 
ATOM   2295  C  C   . GLU B 2 104 ? 31.866  47.841  23.251 1   41.42  ? 85  GLU L C   1 
ATOM   2296  O  O   . GLU B 2 104 ? 30.837  48.485  23.544 1   44.35  ? 85  GLU L O   1 
ATOM   2297  C  CB  . GLU B 2 104 ? 33.241  49.735  22.317 1   44.14  ? 85  GLU L CB  1 
ATOM   2298  C  CG  . GLU B 2 104 ? 34.498  50.052  21.527 1   45.11  ? 85  GLU L CG  1 
ATOM   2299  C  CD  . GLU B 2 104 ? 35.237  51.288  21.999 1   44.7   ? 85  GLU L CD  1 
ATOM   2300  O  OE1 . GLU B 2 104 ? 34.562  52.288  22.307 1   48.59  ? 85  GLU L OE1 1 
ATOM   2301  O  OE2 . GLU B 2 104 ? 36.479  51.255  22.049 1   42.48  ? 85  GLU L OE2 1 
ATOM   2302  N  N   . ALA B 2 105 ? 32.284  46.746  23.882 1   38.76  ? 86  ALA L N   1 
ATOM   2303  C  CA  . ALA B 2 105 ? 31.512  46.026  24.918 1   39.56  ? 86  ALA L CA  1 
ATOM   2304  C  C   . ALA B 2 105 ? 32.377  44.929  25.532 1   39.15  ? 86  ALA L C   1 
ATOM   2305  O  O   . ALA B 2 105 ? 33.466  44.664  24.995 1   40.04  ? 86  ALA L O   1 
ATOM   2306  C  CB  . ALA B 2 105 ? 30.259  45.436  24.315 1   39.46  ? 86  ALA L CB  1 
ATOM   2307  N  N   . ASP B 2 106 ? 31.896  44.322  26.617 1   38.52  ? 87  ASP L N   1 
ATOM   2308  C  CA  . ASP B 2 106 ? 32.478  43.085  27.191 1   39.39  ? 87  ASP L CA  1 
ATOM   2309  C  C   . ASP B 2 106 ? 31.745  41.898  26.568 1   37.03  ? 87  ASP L C   1 
ATOM   2310  O  O   . ASP B 2 106 ? 30.505  41.901  26.597 1   38.06  ? 87  ASP L O   1 
ATOM   2311  C  CB  . ASP B 2 106 ? 32.413  43.097  28.717 1   42.12  ? 87  ASP L CB  1 
ATOM   2312  C  CG  . ASP B 2 106 ? 33.294  44.161  29.349 1   44.7   ? 87  ASP L CG  1 
ATOM   2313  O  OD1 . ASP B 2 106 ? 34.056  44.816  28.603 1   49.1   ? 87  ASP L OD1 1 
ATOM   2314  O  OD2 . ASP B 2 106 ? 33.212  44.329  30.583 1   47.01  ? 87  ASP L OD2 1 
ATOM   2315  N  N   . TYR B 2 107 ? 32.498  40.946  26.015 1   35.03  ? 88  TYR L N   1 
ATOM   2316  C  CA  . TYR B 2 107 ? 31.994  39.706  25.377 1   34.48  ? 88  TYR L CA  1 
ATOM   2317  C  C   . TYR B 2 107 ? 32.359  38.512  26.257 1   35.08  ? 88  TYR L C   1 
ATOM   2318  O  O   . TYR B 2 107 ? 33.555  38.336  26.561 1   35.48  ? 88  TYR L O   1 
ATOM   2319  C  CB  . TYR B 2 107 ? 32.57   39.58   23.967 1   34.39  ? 88  TYR L CB  1 
ATOM   2320  C  CG  . TYR B 2 107 ? 32.071  40.65   23.036 1   34.62  ? 88  TYR L CG  1 
ATOM   2321  C  CD1 . TYR B 2 107 ? 32.607  41.928  23.068 1   35.65  ? 88  TYR L CD1 1 
ATOM   2322  C  CD2 . TYR B 2 107 ? 31.026  40.402  22.161 1   35.21  ? 88  TYR L CD2 1 
ATOM   2323  C  CE1 . TYR B 2 107 ? 32.129  42.928  22.237 1   35.69  ? 88  TYR L CE1 1 
ATOM   2324  C  CE2 . TYR B 2 107 ? 30.538  41.391  21.324 1   35.22  ? 88  TYR L CE2 1 
ATOM   2325  C  CZ  . TYR B 2 107 ? 31.096  42.655  21.359 1   35.59  ? 88  TYR L CZ  1 
ATOM   2326  O  OH  . TYR B 2 107 ? 30.61   43.626  20.537 1   38.38  ? 88  TYR L OH  1 
ATOM   2327  N  N   . TYR B 2 108 ? 31.354  37.732  26.663 1   36.57  ? 89  TYR L N   1 
ATOM   2328  C  CA  . TYR B 2 108 ? 31.511  36.458  27.413 1   37.25  ? 89  TYR L CA  1 
ATOM   2329  C  C   . TYR B 2 108 ? 31.069  35.296  26.525 1   38.58  ? 89  TYR L C   1 
ATOM   2330  O  O   . TYR B 2 108 ? 29.988  35.39   25.927 1   39.02  ? 89  TYR L O   1 
ATOM   2331  C  CB  . TYR B 2 108 ? 30.693  36.471  28.704 1   36.42  ? 89  TYR L CB  1 
ATOM   2332  C  CG  . TYR B 2 108 ? 31.083  37.566  29.659 1   35.62  ? 89  TYR L CG  1 
ATOM   2333  C  CD1 . TYR B 2 108 ? 32.074  37.364  30.605 1   35.95  ? 89  TYR L CD1 1 
ATOM   2334  C  CD2 . TYR B 2 108 ? 30.472  38.808  29.608 1   34.65  ? 89  TYR L CD2 1 
ATOM   2335  C  CE1 . TYR B 2 108 ? 32.45   38.368  31.481 1   35.91  ? 89  TYR L CE1 1 
ATOM   2336  C  CE2 . TYR B 2 108 ? 30.833  39.821  30.48  1   35.33  ? 89  TYR L CE2 1 
ATOM   2337  C  CZ  . TYR B 2 108 ? 31.83   39.602  31.414 1   35.03  ? 89  TYR L CZ  1 
ATOM   2338  O  OH  . TYR B 2 108 ? 32.196  40.588  32.277 1   37.3   ? 89  TYR L OH  1 
ATOM   2339  N  N   . CYS B 2 109 ? 31.907  34.264  26.421 1   41.23  ? 90  CYS L N   1 
ATOM   2340  C  CA  . CYS B 2 109 ? 31.514  32.897  25.996 1   43.02  ? 90  CYS L CA  1 
ATOM   2341  C  C   . CYS B 2 109 ? 31.009  32.143  27.23  1   41.1   ? 90  CYS L C   1 
ATOM   2342  O  O   . CYS B 2 109 ? 31.48   32.439  28.348 1   40.96  ? 90  CYS L O   1 
ATOM   2343  C  CB  . CYS B 2 109 ? 32.673  32.138  25.361 1   45.12  ? 90  CYS L CB  1 
ATOM   2344  S  SG  . CYS B 2 109 ? 34.065  31.858  26.489 1   51.74  ? 90  CYS L SG  1 
ATOM   2345  N  N   . ALA B 2 110 ? 30.095  31.199  27.032 1   39.97  ? 91  ALA L N   1 
ATOM   2346  C  CA  . ALA B 2 110 ? 29.677  30.215  28.056 1   40.01  ? 91  ALA L CA  1 
ATOM   2347  C  C   . ALA B 2 110 ? 29.552  28.845  27.392 1   39.46  ? 91  ALA L C   1 
ATOM   2348  O  O   . ALA B 2 110 ? 29.381  28.81   26.153 1   38.46  ? 91  ALA L O   1 
ATOM   2349  C  CB  . ALA B 2 110 ? 28.38   30.636  28.701 1   38.74  ? 91  ALA L CB  1 
ATOM   2350  N  N   . SER B 2 111 ? 29.661  27.775  28.184 1   39.33  ? 92  SER L N   1 
ATOM   2351  C  CA  . SER B 2 111 ? 29.388  26.378  27.758 1   40.82  ? 92  SER L CA  1 
ATOM   2352  C  C   . SER B 2 111 ? 28.753  25.574  28.895 1   42.01  ? 92  SER L C   1 
ATOM   2353  O  O   . SER B 2 111 ? 29.09   25.811  30.078 1   41.71  ? 92  SER L O   1 
ATOM   2354  C  CB  . SER B 2 111 ? 30.627  25.691  27.263 1   42.17  ? 92  SER L CB  1 
ATOM   2355  O  OG  . SER B 2 111 ? 30.373  24.307  27.038 1   42.28  ? 92  SER L OG  1 
ATOM   2356  N  N   . HIS B 2 112 ? 27.886  24.634  28.523 1   45.03  ? 93  HIS L N   1 
ATOM   2357  C  CA  . HIS B 2 112 ? 27.452  23.502  29.382 1   48.61  ? 93  HIS L CA  1 
ATOM   2358  C  C   . HIS B 2 112 ? 28.667  22.61   29.667 1   48.27  ? 93  HIS L C   1 
ATOM   2359  O  O   . HIS B 2 112 ? 29.317  22.187  28.698 1   48.33  ? 93  HIS L O   1 
ATOM   2360  C  CB  . HIS B 2 112 ? 26.311  22.715  28.717 1   50.22  ? 93  HIS L CB  1 
ATOM   2361  C  CG  . HIS B 2 112 ? 25.945  21.472  29.456 1   51.44  ? 93  HIS L CG  1 
ATOM   2362  N  ND1 . HIS B 2 112 ? 26.354  20.222  29.033 1   52.62  ? 93  HIS L ND1 1 
ATOM   2363  C  CD2 . HIS B 2 112 ? 25.25   21.285  30.598 1   49.34  ? 93  HIS L CD2 1 
ATOM   2364  C  CE1 . HIS B 2 112 ? 25.913  19.316  29.876 1   52.37  ? 93  HIS L CE1 1 
ATOM   2365  N  NE2 . HIS B 2 112 ? 25.233  19.943  30.845 1   51.24  ? 93  HIS L NE2 1 
ATOM   2366  N  N   . ARG B 2 113 ? 28.965  22.367  30.945 1   50.41  ? 94  ARG L N   1 
ATOM   2367  C  CA  . ARG B 2 113 ? 29.984  21.387  31.407 1   55.47  ? 94  ARG L CA  1 
ATOM   2368  C  C   . ARG B 2 113 ? 29.255  20.102  31.831 1   58.07  ? 94  ARG L C   1 
ATOM   2369  O  O   . ARG B 2 113 ? 28.024  20.156  32.004 1   57.34  ? 94  ARG L O   1 
ATOM   2370  C  CB  . ARG B 2 113 ? 30.832  22.021  32.516 1   55.66  ? 94  ARG L CB  1 
ATOM   2371  C  CG  . ARG B 2 113 ? 32.044  21.204  32.935 1   56.36  ? 94  ARG L CG  1 
ATOM   2372  C  CD  . ARG B 2 113 ? 33.058  22.012  33.721 1   56.56  ? 94  ARG L CD  1 
ATOM   2373  N  NE  . ARG B 2 113 ? 33.904  22.838  32.868 1   59.25  ? 94  ARG L NE  1 
ATOM   2374  C  CZ  . ARG B 2 113 ? 34.88   23.643  33.299 1   62.91  ? 94  ARG L CZ  1 
ATOM   2375  N  NH1 . ARG B 2 113 ? 35.152  23.746  34.593 1   65.4   ? 94  ARG L NH1 1 
ATOM   2376  N  NH2 . ARG B 2 113 ? 35.582  24.352  32.428 1   62.3   ? 94  ARG L NH2 1 
ATOM   2377  N  N   . SER B 2 114 ? 29.984  18.988  31.97  1   62.21  ? 95  SER L N   1 
ATOM   2378  C  CA  . SER B 2 114 ? 29.447  17.636  32.301 1   64.1   ? 95  SER L CA  1 
ATOM   2379  C  C   . SER B 2 114 ? 28.865  17.587  33.722 1   65.45  ? 95  SER L C   1 
ATOM   2380  O  O   . SER B 2 114 ? 28.07   16.663  33.985 1   65.5   ? 95  SER L O   1 
ATOM   2381  C  CB  . SER B 2 114 ? 30.503  16.575  32.112 1   63.7   ? 95  SER L CB  1 
ATOM   2382  O  OG  . SER B 2 114 ? 30.944  16.535  30.764 1   62.32  ? 95  SER L OG  1 
ATOM   2383  N  N   . ASN B 2 115 ? 29.227  18.542  34.591 1   66.79  ? 96  ASN L N   1 
ATOM   2384  C  CA  . ASN B 2 115 ? 28.674  18.716  35.965 1   70.25  ? 96  ASN L CA  1 
ATOM   2385  C  C   . ASN B 2 115 ? 27.151  18.937  35.954 1   71.92  ? 96  ASN L C   1 
ATOM   2386  O  O   . ASN B 2 115 ? 26.536  18.709  37.011 1   74.58  ? 96  ASN L O   1 
ATOM   2387  C  CB  . ASN B 2 115 ? 29.263  19.938  36.679 1   73.94  ? 96  ASN L CB  1 
ATOM   2388  C  CG  . ASN B 2 115 ? 30.768  19.903  36.842 1   77.34  ? 96  ASN L CG  1 
ATOM   2389  O  OD1 . ASN B 2 115 ? 31.305  18.986  37.461 1   85.78  ? 96  ASN L OD1 1 
ATOM   2390  N  ND2 . ASN B 2 115 ? 31.454  20.911  36.322 1   76.31  ? 96  ASN L ND2 1 
ATOM   2391  N  N   . ASN B 2 116 ? 26.578  19.372  34.82  1   71.44  ? 97  ASN L N   1 
ATOM   2392  C  CA  . ASN B 2 116 ? 25.31   20.147  34.714 1   70.28  ? 97  ASN L CA  1 
ATOM   2393  C  C   . ASN B 2 116 ? 25.555  21.537  35.318 1   65.62  ? 97  ASN L C   1 
ATOM   2394  O  O   . ASN B 2 116 ? 24.621  22.107  35.912 1   71.24  ? 97  ASN L O   1 
ATOM   2395  C  CB  . ASN B 2 116 ? 24.106  19.408  35.307 1   73.46  ? 97  ASN L CB  1 
ATOM   2396  C  CG  . ASN B 2 116 ? 23.842  18.084  34.62  1   78.85  ? 97  ASN L CG  1 
ATOM   2397  O  OD1 . ASN B 2 116 ? 23.814  18.012  33.391 1   84.31  ? 97  ASN L OD1 1 
ATOM   2398  N  ND2 . ASN B 2 116 ? 23.636  17.032  35.396 1   80.15  ? 97  ASN L ND2 1 
ATOM   2399  N  N   . ASN B 2 117 ? 26.779  22.047  35.153 1   59.89  ? 98  ASN L N   1 
ATOM   2400  C  CA  . ASN B 2 117 ? 27.165  23.465  35.357 1   57.15  ? 98  ASN L CA  1 
ATOM   2401  C  C   . ASN B 2 117 ? 27.059  24.178  34.011 1   56.27  ? 98  ASN L C   1 
ATOM   2402  O  O   . ASN B 2 117 ? 27.175  23.503  32.97  1   56.59  ? 98  ASN L O   1 
ATOM   2403  C  CB  . ASN B 2 117 ? 28.597  23.622  35.875 1   56.33  ? 98  ASN L CB  1 
ATOM   2404  C  CG  . ASN B 2 117 ? 28.735  23.333  37.353 1   56.52  ? 98  ASN L CG  1 
ATOM   2405  O  OD1 . ASN B 2 117 ? 27.997  22.514  37.899 1   57.84  ? 98  ASN L OD1 1 
ATOM   2406  N  ND2 . ASN B 2 117 ? 29.671  24.001  38.009 1   54.61  ? 98  ASN L ND2 1 
ATOM   2407  N  N   . ILE B 2 118 ? 26.845  25.491  34.036 1   55.36  ? 99  ILE L N   1 
ATOM   2408  C  CA  . ILE B 2 118 ? 27.101  26.388  32.872 1   53.58  ? 99  ILE L CA  1 
ATOM   2409  C  C   . ILE B 2 118 ? 28.32   27.227  33.253 1   49.42  ? 99  ILE L C   1 
ATOM   2410  O  O   . ILE B 2 118 ? 28.252  27.924  34.266 1   48.65  ? 99  ILE L O   1 
ATOM   2411  C  CB  . ILE B 2 118 ? 25.851  27.213  32.504 1   54.91  ? 99  ILE L CB  1 
ATOM   2412  C  CG1 . ILE B 2 118 ? 24.728  26.299  32.004 1   56.07  ? 99  ILE L CG1 1 
ATOM   2413  C  CG2 . ILE B 2 118 ? 26.185  28.291  31.48  1   55.95  ? 99  ILE L CG2 1 
ATOM   2414  C  CD1 . ILE B 2 118 ? 23.347  26.908  32.066 1   57.97  ? 99  ILE L CD1 1 
ATOM   2415  N  N   . VAL B 2 119 ? 29.407  27.095  32.494 1   47.74  ? 100 VAL L N   1 
ATOM   2416  C  CA  . VAL B 2 119 ? 30.729  27.718  32.786 1   47.26  ? 100 VAL L CA  1 
ATOM   2417  C  C   . VAL B 2 119 ? 30.888  28.929  31.865 1   44.43  ? 100 VAL L C   1 
ATOM   2418  O  O   . VAL B 2 119 ? 30.732  28.75   30.651 1   42.93  ? 100 VAL L O   1 
ATOM   2419  C  CB  . VAL B 2 119 ? 31.869  26.699  32.598 1   49.45  ? 100 VAL L CB  1 
ATOM   2420  C  CG1 . VAL B 2 119 ? 33.203  27.231  33.093 1   50.54  ? 100 VAL L CG1 1 
ATOM   2421  C  CG2 . VAL B 2 119 ? 31.547  25.388  33.291 1   50.82  ? 100 VAL L CG2 1 
ATOM   2422  N  N   . PHE B 2 120 ? 31.149  30.107  32.443 1   43.86  ? 101 PHE L N   1 
ATOM   2423  C  CA  . PHE B 2 120 ? 31.432  31.379  31.723 1   42.68  ? 101 PHE L CA  1 
ATOM   2424  C  C   . PHE B 2 120 ? 32.944  31.513  31.528 1   42.45  ? 101 PHE L C   1 
ATOM   2425  O  O   . PHE B 2 120 ? 33.71   31.02   32.373 1   43.23  ? 101 PHE L O   1 
ATOM   2426  C  CB  . PHE B 2 120 ? 30.89   32.601  32.477 1   39.49  ? 101 PHE L CB  1 
ATOM   2427  C  CG  . PHE B 2 120 ? 29.441  32.913  32.198 1   39.41  ? 101 PHE L CG  1 
ATOM   2428  C  CD1 . PHE B 2 120 ? 29.071  33.589  31.042 1   38.09  ? 101 PHE L CD1 1 
ATOM   2429  C  CD2 . PHE B 2 120 ? 28.446  32.519  33.081 1   38.81  ? 101 PHE L CD2 1 
ATOM   2430  C  CE1 . PHE B 2 120 ? 27.737  33.859  30.776 1   37.03  ? 101 PHE L CE1 1 
ATOM   2431  C  CE2 . PHE B 2 120 ? 27.112  32.785  32.811 1   37.48  ? 101 PHE L CE2 1 
ATOM   2432  C  CZ  . PHE B 2 120 ? 26.761  33.458  31.66  1   37.64  ? 101 PHE L CZ  1 
ATOM   2433  N  N   . GLY B 2 121 ? 33.349  32.183  30.45  1   43.24  ? 102 GLY L N   1 
ATOM   2434  C  CA  . GLY B 2 121 ? 34.728  32.671  30.278 1   43.81  ? 102 GLY L CA  1 
ATOM   2435  C  C   . GLY B 2 121 ? 34.988  33.898  31.134 1   45.49  ? 102 GLY L C   1 
ATOM   2436  O  O   . GLY B 2 121 ? 34.014  34.48   31.655 1   44.31  ? 102 GLY L O   1 
ATOM   2437  N  N   . GLY B 2 122 ? 36.261  34.286  31.267 1   47.2   ? 103 GLY L N   1 
ATOM   2438  C  CA  . GLY B 2 122 ? 36.708  35.43   32.086 1   45.99  ? 103 GLY L CA  1 
ATOM   2439  C  C   . GLY B 2 122 ? 36.223  36.767  31.549 1   45.07  ? 103 GLY L C   1 
ATOM   2440  O  O   . GLY B 2 122 ? 36.346  37.756  32.286 1   48     ? 103 GLY L O   1 
ATOM   2441  N  N   . GLY B 2 123 ? 35.716  36.81   30.311 1   43.71  ? 104 GLY L N   1 
ATOM   2442  C  CA  . GLY B 2 123 ? 35.237  38.033  29.638 1   43.01  ? 104 GLY L CA  1 
ATOM   2443  C  C   . GLY B 2 123 ? 36.353  38.719  28.874 1   41.83  ? 104 GLY L C   1 
ATOM   2444  O  O   . GLY B 2 123 ? 37.504  38.649  29.335 1   40.61  ? 104 GLY L O   1 
ATOM   2445  N  N   . THR B 2 124 ? 36.021  39.361  27.75  1   41.59  ? 105 THR L N   1 
ATOM   2446  C  CA  . THR B 2 124 ? 36.963  40.111  26.878 1   41.94  ? 105 THR L CA  1 
ATOM   2447  C  C   . THR B 2 124 ? 36.404  41.511  26.624 1   42.6   ? 105 THR L C   1 
ATOM   2448  O  O   . THR B 2 124 ? 35.285  41.6    26.1   1   40.16  ? 105 THR L O   1 
ATOM   2449  C  CB  . THR B 2 124 ? 37.195  39.383  25.55  1   42.59  ? 105 THR L CB  1 
ATOM   2450  O  OG1 . THR B 2 124 ? 37.694  38.079  25.846 1   41.61  ? 105 THR L OG1 1 
ATOM   2451  C  CG2 . THR B 2 124 ? 38.155  40.11   24.632 1   42.83  ? 105 THR L CG2 1 
ATOM   2452  N  N   . LYS B 2 125 ? 37.176  42.546  26.967 1   46.08  ? 106 LYS L N   1 
ATOM   2453  C  CA  . LYS B 2 125 ? 36.882  43.966  26.641 1   47.36  ? 106 LYS L CA  1 
ATOM   2454  C  C   . LYS B 2 125 ? 37.304  44.214  25.187 1   44.56  ? 106 LYS L C   1 
ATOM   2455  O  O   . LYS B 2 125 ? 38.49   44.016  24.892 1   44.6   ? 106 LYS L O   1 
ATOM   2456  C  CB  . LYS B 2 125 ? 37.615  44.888  27.621 1   50.24  ? 106 LYS L CB  1 
ATOM   2457  C  CG  . LYS B 2 125 ? 37.119  46.327  27.658 1   54.31  ? 106 LYS L CG  1 
ATOM   2458  C  CD  . LYS B 2 125 ? 38.143  47.303  28.206 1   57.85  ? 106 LYS L CD  1 
ATOM   2459  C  CE  . LYS B 2 125 ? 37.67   48.742  28.17  1   59.36  ? 106 LYS L CE  1 
ATOM   2460  N  NZ  . LYS B 2 125 ? 38.808  49.692  28.167 1   61.8   ? 106 LYS L NZ  1 
ATOM   2461  N  N   . LEU B 2 126 ? 36.361  44.586  24.315 1   43.5   ? 107 LEU L N   1 
ATOM   2462  C  CA  . LEU B 2 126 ? 36.615  44.943  22.892 1   43.59  ? 107 LEU L CA  1 
ATOM   2463  C  C   . LEU B 2 126 ? 36.737  46.473  22.782 1   44.45  ? 107 LEU L C   1 
ATOM   2464  O  O   . LEU B 2 126 ? 35.743  47.169  23.072 1   44.04  ? 107 LEU L O   1 
ATOM   2465  C  CB  . LEU B 2 126 ? 35.493  44.382  22.007 1   43.53  ? 107 LEU L CB  1 
ATOM   2466  C  CG  . LEU B 2 126 ? 35.514  44.774  20.523 1   44.46  ? 107 LEU L CG  1 
ATOM   2467  C  CD1 . LEU B 2 126 ? 36.871  44.539  19.881 1   44.56  ? 107 LEU L CD1 1 
ATOM   2468  C  CD2 . LEU B 2 126 ? 34.451  44.016  19.743 1   44.77  ? 107 LEU L CD2 1 
ATOM   2469  N  N   . THR B 2 127 ? 37.927  46.967  22.413 1   45.03  ? 108 THR L N   1 
ATOM   2470  C  CA  . THR B 2 127 ? 38.229  48.398  22.132 1   44.52  ? 108 THR L CA  1 
ATOM   2471  C  C   . THR B 2 127 ? 38.307  48.588  20.614 1   43.81  ? 108 THR L C   1 
ATOM   2472  O  O   . THR B 2 127 ? 38.865  47.702  19.943 1   43.63  ? 108 THR L O   1 
ATOM   2473  C  CB  . THR B 2 127 ? 39.52   48.845  22.832 1   45.41  ? 108 THR L CB  1 
ATOM   2474  O  OG1 . THR B 2 127 ? 39.312  48.739  24.242 1   45.5   ? 108 THR L OG1 1 
ATOM   2475  C  CG2 . THR B 2 127 ? 39.928  50.266  22.501 1   47.13  ? 108 THR L CG2 1 
ATOM   2476  N  N   . VAL B 2 128 ? 37.78   49.705  20.108 1   42.22  ? 109 VAL L N   1 
ATOM   2477  C  CA  . VAL B 2 128 ? 37.825  50.086  18.664 1   43.49  ? 109 VAL L CA  1 
ATOM   2478  C  C   . VAL B 2 128 ? 38.713  51.331  18.54  1   43.93  ? 109 VAL L C   1 
ATOM   2479  O  O   . VAL B 2 128 ? 38.421  52.333  19.209 1   45.25  ? 109 VAL L O   1 
ATOM   2480  C  CB  . VAL B 2 128 ? 36.411  50.303  18.09  1   44.05  ? 109 VAL L CB  1 
ATOM   2481  C  CG1 . VAL B 2 128 ? 36.437  50.717  16.624 1   44.52  ? 109 VAL L CG1 1 
ATOM   2482  C  CG2 . VAL B 2 128 ? 35.546  49.065  18.261 1   43.99  ? 109 VAL L CG2 1 
ATOM   2483  N  N   . LEU B 2 129 ? 39.758  51.262  17.713 1   44.83  ? 110 LEU L N   1 
ATOM   2484  C  CA  . LEU B 2 129 ? 40.839  52.282  17.64  1   45     ? 110 LEU L CA  1 
ATOM   2485  C  C   . LEU B 2 129 ? 40.404  53.479  16.788 1   42.63  ? 110 LEU L C   1 
ATOM   2486  O  O   . LEU B 2 129 ? 39.393  53.382  16.079 1   42.14  ? 110 LEU L O   1 
ATOM   2487  C  CB  . LEU B 2 129 ? 42.095  51.64   17.045 1   47.77  ? 110 LEU L CB  1 
ATOM   2488  C  CG  . LEU B 2 129 ? 42.659  50.444  17.812 1   50.01  ? 110 LEU L CG  1 
ATOM   2489  C  CD1 . LEU B 2 129 ? 43.669  49.692  16.959 1   50.28  ? 110 LEU L CD1 1 
ATOM   2490  C  CD2 . LEU B 2 129 ? 43.286  50.883  19.127 1   50.8   ? 110 LEU L CD2 1 
ATOM   2491  N  N   . GLY B 2 130 ? 41.167  54.571  16.877 1   44.67  ? 111 GLY L N   1 
ATOM   2492  C  CA  . GLY B 2 130 ? 41.088  55.751  15.994 1   46.86  ? 111 GLY L CA  1 
ATOM   2493  C  C   . GLY B 2 130 ? 39.76   56.487  16.071 1   46.18  ? 111 GLY L C   1 
ATOM   2494  O  O   . GLY B 2 130 ? 39.37   57.086  15.056 1   48.99  ? 111 GLY L O   1 
ATOM   2495  N  N   . GLN B 2 131 ? 39.091  56.463  17.224 1   46.56  ? 112 GLN L N   1 
ATOM   2496  C  CA  . GLN B 2 131 ? 37.869  57.267  17.484 1   46.68  ? 112 GLN L CA  1 
ATOM   2497  C  C   . GLN B 2 131 ? 38.297  58.703  17.764 1   43.83  ? 112 GLN L C   1 
ATOM   2498  O  O   . GLN B 2 131 ? 39.271  58.917  18.477 1   44.44  ? 112 GLN L O   1 
ATOM   2499  C  CB  . GLN B 2 131 ? 37.093  56.714  18.677 1   48.66  ? 112 GLN L CB  1 
ATOM   2500  C  CG  . GLN B 2 131 ? 36.659  55.268  18.508 1   50.63  ? 112 GLN L CG  1 
ATOM   2501  C  CD  . GLN B 2 131 ? 35.718  54.874  19.62  1   52.33  ? 112 GLN L CD  1 
ATOM   2502  O  OE1 . GLN B 2 131 ? 34.595  55.365  19.697 1   54.67  ? 112 GLN L OE1 1 
ATOM   2503  N  NE2 . GLN B 2 131 ? 36.182  54.019  20.519 1   53.93  ? 112 GLN L NE2 1 
ATOM   2504  N  N   . PRO B 2 132 ? 37.578  59.729  17.257 1   44.32  ? 113 PRO L N   1 
ATOM   2505  C  CA  . PRO B 2 132 ? 38.033  61.113  17.392 1   45.78  ? 113 PRO L CA  1 
ATOM   2506  C  C   . PRO B 2 132 ? 37.991  61.594  18.85  1   46.93  ? 113 PRO L C   1 
ATOM   2507  O  O   . PRO B 2 132 ? 37.165  61.109  19.609 1   50.37  ? 113 PRO L O   1 
ATOM   2508  C  CB  . PRO B 2 132 ? 37.047  61.904  16.519 1   44.74  ? 113 PRO L CB  1 
ATOM   2509  C  CG  . PRO B 2 132 ? 35.787  61.063  16.54  1   45.22  ? 113 PRO L CG  1 
ATOM   2510  C  CD  . PRO B 2 132 ? 36.269  59.627  16.591 1   44.57  ? 113 PRO L CD  1 
ATOM   2511  N  N   . LYS B 2 133 ? 38.877  62.526  19.206 1   49.19  ? 114 LYS L N   1 
ATOM   2512  C  CA  . LYS B 2 133 ? 38.902  63.151  20.557 1   51.21  ? 114 LYS L CA  1 
ATOM   2513  C  C   . LYS B 2 133 ? 37.675  64.072  20.67  1   49.6   ? 114 LYS L C   1 
ATOM   2514  O  O   . LYS B 2 133 ? 37.383  64.793  19.694 1   49.84  ? 114 LYS L O   1 
ATOM   2515  C  CB  . LYS B 2 133 ? 40.245  63.844  20.833 1   51.85  ? 114 LYS L CB  1 
ATOM   2516  C  CG  . LYS B 2 133 ? 40.195  65.346  21.083 1   55.65  ? 114 LYS L CG  1 
ATOM   2517  C  CD  . LYS B 2 133 ? 41.545  65.943  21.402 1   57.41  ? 114 LYS L CD  1 
ATOM   2518  C  CE  . LYS B 2 133 ? 41.575  67.448  21.251 1   58.34  ? 114 LYS L CE  1 
ATOM   2519  N  NZ  . LYS B 2 133 ? 42.97   67.945  21.208 1   60.15  ? 114 LYS L NZ  1 
ATOM   2520  N  N   . ALA B 2 134 ? 36.973  64.015  21.807 1   47.08  ? 115 ALA L N   1 
ATOM   2521  C  CA  . ALA B 2 134 ? 35.786  64.844  22.129 1   45.7   ? 115 ALA L CA  1 
ATOM   2522  C  C   . ALA B 2 134 ? 36.033  65.576  23.452 1   45.38  ? 115 ALA L C   1 
ATOM   2523  O  O   . ALA B 2 134 ? 36.398  64.907  24.438 1   44.12  ? 115 ALA L O   1 
ATOM   2524  C  CB  . ALA B 2 134 ? 34.559  63.976  22.194 1   45.25  ? 115 ALA L CB  1 
ATOM   2525  N  N   . ALA B 2 135 ? 35.88   66.905  23.459 1   45.75  ? 116 ALA L N   1 
ATOM   2526  C  CA  . ALA B 2 135 ? 36.082  67.766  24.648 1   45     ? 116 ALA L CA  1 
ATOM   2527  C  C   . ALA B 2 135 ? 34.922  67.546  25.614 1   45.26  ? 116 ALA L C   1 
ATOM   2528  O  O   . ALA B 2 135 ? 33.783  67.363  25.181 1   45.43  ? 116 ALA L O   1 
ATOM   2529  C  CB  . ALA B 2 135 ? 36.19   69.218  24.252 1   43.6   ? 116 ALA L CB  1 
ATOM   2530  N  N   . PRO B 2 136 ? 35.167  67.577  26.943 1   43.48  ? 117 PRO L N   1 
ATOM   2531  C  CA  . PRO B 2 136 ? 34.117  67.324  27.921 1   43.25  ? 117 PRO L CA  1 
ATOM   2532  C  C   . PRO B 2 136 ? 33.133  68.496  27.981 1   42.46  ? 117 PRO L C   1 
ATOM   2533  O  O   . PRO B 2 136 ? 33.56   69.622  27.922 1   43.06  ? 117 PRO L O   1 
ATOM   2534  C  CB  . PRO B 2 136 ? 34.876  67.17   29.247 1   43.44  ? 117 PRO L CB  1 
ATOM   2535  C  CG  . PRO B 2 136 ? 36.118  68.007  29.06  1   44.54  ? 117 PRO L CG  1 
ATOM   2536  C  CD  . PRO B 2 136 ? 36.448  67.908  27.584 1   45.23  ? 117 PRO L CD  1 
ATOM   2537  N  N   . SER B 2 137 ? 31.841  68.185  28.052 1   44.07  ? 118 SER L N   1 
ATOM   2538  C  CA  . SER B 2 137 ? 30.777  69.13   28.467 1   42.69  ? 118 SER L CA  1 
ATOM   2539  C  C   . SER B 2 137 ? 30.826  69.213  29.996 1   40.99  ? 118 SER L C   1 
ATOM   2540  O  O   . SER B 2 137 ? 30.815  68.146  30.633 1   40.46  ? 118 SER L O   1 
ATOM   2541  C  CB  . SER B 2 137 ? 29.437  68.688  27.947 1   43.09  ? 118 SER L CB  1 
ATOM   2542  O  OG  . SER B 2 137 ? 28.477  69.724  28.078 1   46.72  ? 118 SER L OG  1 
ATOM   2543  N  N   . VAL B 2 138 ? 30.942  70.421  30.553 1   38.56  ? 119 VAL L N   1 
ATOM   2544  C  CA  . VAL B 2 138 ? 31.091  70.661  32.019 1   39.1   ? 119 VAL L CA  1 
ATOM   2545  C  C   . VAL B 2 138 ? 29.919  71.529  32.494 1   39.43  ? 119 VAL L C   1 
ATOM   2546  O  O   . VAL B 2 138 ? 29.668  72.578  31.869 1   40.17  ? 119 VAL L O   1 
ATOM   2547  C  CB  . VAL B 2 138 ? 32.451  71.304  32.354 1   38.43  ? 119 VAL L CB  1 
ATOM   2548  C  CG1 . VAL B 2 138 ? 32.665  71.439  33.854 1   38.14  ? 119 VAL L CG1 1 
ATOM   2549  C  CG2 . VAL B 2 138 ? 33.599  70.528  31.734 1   39.29  ? 119 VAL L CG2 1 
ATOM   2550  N  N   . THR B 2 139 ? 29.241  71.094  33.559 1   39.21  ? 120 THR L N   1 
ATOM   2551  C  CA  . THR B 2 139 ? 28.138  71.821  34.244 1   38.75  ? 120 THR L CA  1 
ATOM   2552  C  C   . THR B 2 139 ? 28.462  71.883  35.739 1   37.6   ? 120 THR L C   1 
ATOM   2553  O  O   . THR B 2 139 ? 28.584  70.813  36.347 1   35.53  ? 120 THR L O   1 
ATOM   2554  C  CB  . THR B 2 139 ? 26.784  71.139  34.003 1   39.25  ? 120 THR L CB  1 
ATOM   2555  O  OG1 . THR B 2 139 ? 26.528  71.113  32.6   1   38.5   ? 120 THR L OG1 1 
ATOM   2556  C  CG2 . THR B 2 139 ? 25.63   71.832  34.693 1   40.66  ? 120 THR L CG2 1 
ATOM   2557  N  N   . LEU B 2 140 ? 28.589  73.089  36.297 1   39.35  ? 121 LEU L N   1 
ATOM   2558  C  CA  . LEU B 2 140 ? 28.834  73.311  37.745 1   39.32  ? 121 LEU L CA  1 
ATOM   2559  C  C   . LEU B 2 140 ? 27.546  73.823  38.396 1   38.67  ? 121 LEU L C   1 
ATOM   2560  O  O   . LEU B 2 140 ? 27.006  74.829  37.909 1   37.61  ? 121 LEU L O   1 
ATOM   2561  C  CB  . LEU B 2 140 ? 29.983  74.307  37.916 1   40.56  ? 121 LEU L CB  1 
ATOM   2562  C  CG  . LEU B 2 140 ? 30.451  74.55   39.351 1   42.31  ? 121 LEU L CG  1 
ATOM   2563  C  CD1 . LEU B 2 140 ? 30.797  73.249  40.065 1   42.55  ? 121 LEU L CD1 1 
ATOM   2564  C  CD2 . LEU B 2 140 ? 31.648  75.486  39.36  1   42.57  ? 121 LEU L CD2 1 
ATOM   2565  N  N   . PHE B 2 141 ? 27.069  73.127  39.435 1   39.41  ? 122 PHE L N   1 
ATOM   2566  C  CA  . PHE B 2 141 ? 25.876  73.491  40.244 1   37.8   ? 122 PHE L CA  1 
ATOM   2567  C  C   . PHE B 2 141 ? 26.338  73.969  41.613 1   36.99  ? 122 PHE L C   1 
ATOM   2568  O  O   . PHE B 2 141 ? 27.122  73.281  42.263 1   36.25  ? 122 PHE L O   1 
ATOM   2569  C  CB  . PHE B 2 141 ? 24.927  72.302  40.41  1   37.8   ? 122 PHE L CB  1 
ATOM   2570  C  CG  . PHE B 2 141 ? 24.108  71.978  39.188 1   39.87  ? 122 PHE L CG  1 
ATOM   2571  C  CD1 . PHE B 2 141 ? 22.988  72.732  38.867 1   39.81  ? 122 PHE L CD1 1 
ATOM   2572  C  CD2 . PHE B 2 141 ? 24.455  70.924  38.353 1   40.54  ? 122 PHE L CD2 1 
ATOM   2573  C  CE1 . PHE B 2 141 ? 22.229  72.434  37.744 1   40.3   ? 122 PHE L CE1 1 
ATOM   2574  C  CE2 . PHE B 2 141 ? 23.694  70.629  37.231 1   41.14  ? 122 PHE L CE2 1 
ATOM   2575  C  CZ  . PHE B 2 141 ? 22.583  71.385  36.928 1   41.26  ? 122 PHE L CZ  1 
ATOM   2576  N  N   . PRO B 2 142 ? 25.838  75.125  42.108 1   37.89  ? 123 PRO L N   1 
ATOM   2577  C  CA  . PRO B 2 142 ? 26.141  75.582  43.461 1   37.99  ? 123 PRO L CA  1 
ATOM   2578  C  C   . PRO B 2 142 ? 25.24   74.856  44.456 1   36.65  ? 123 PRO L C   1 
ATOM   2579  O  O   . PRO B 2 142 ? 24.296  74.179  44.048 1   35.56  ? 123 PRO L O   1 
ATOM   2580  C  CB  . PRO B 2 142 ? 25.82   77.081  43.372 1   40.22  ? 123 PRO L CB  1 
ATOM   2581  C  CG  . PRO B 2 142 ? 24.631  77.136  42.433 1   39.4   ? 123 PRO L CG  1 
ATOM   2582  C  CD  . PRO B 2 142 ? 24.896  76.031  41.427 1   40.19  ? 123 PRO L CD  1 
ATOM   2583  N  N   . PRO B 2 143 ? 25.472  74.983  45.783 1   35.91  ? 124 PRO L N   1 
ATOM   2584  C  CA  . PRO B 2 143 ? 24.619  74.326  46.767 1   35.7   ? 124 PRO L CA  1 
ATOM   2585  C  C   . PRO B 2 143 ? 23.178  74.84   46.64  1   37.32  ? 124 PRO L C   1 
ATOM   2586  O  O   . PRO B 2 143 ? 22.979  76.023  46.395 1   38.25  ? 124 PRO L O   1 
ATOM   2587  C  CB  . PRO B 2 143 ? 25.207  74.702  48.137 1   35.74  ? 124 PRO L CB  1 
ATOM   2588  C  CG  . PRO B 2 143 ? 26.571  75.295  47.841 1   36.37  ? 124 PRO L CG  1 
ATOM   2589  C  CD  . PRO B 2 143 ? 26.517  75.802  46.413 1   36.19  ? 124 PRO L CD  1 
ATOM   2590  N  N   . SER B 2 144 ? 22.21   73.936  46.776 1   39.72  ? 125 SER L N   1 
ATOM   2591  C  CA  A SER B 2 144 ? 20.763  74.269  46.777 0.5 40.55  ? 125 SER L CA  1 
ATOM   2592  C  CA  B SER B 2 144 ? 20.763  74.269  46.777 0.5 40.54  ? 125 SER L CA  1 
ATOM   2593  C  C   . SER B 2 144 ? 20.417  74.98   48.089 1   41.85  ? 125 SER L C   1 
ATOM   2594  O  O   . SER B 2 144 ? 21.085  74.687  49.1   1   43.69  ? 125 SER L O   1 
ATOM   2595  C  CB  A SER B 2 144 ? 19.923  73.036  46.584 0.5 40.37  ? 125 SER L CB  1 
ATOM   2596  C  CB  B SER B 2 144 ? 19.923  73.036  46.584 0.5 40.36  ? 125 SER L CB  1 
ATOM   2597  O  OG  A SER B 2 144 ? 19.95   72.219  47.744 0.5 40.77  ? 125 SER L OG  1 
ATOM   2598  O  OG  B SER B 2 144 ? 19.95   72.219  47.744 0.5 40.76  ? 125 SER L OG  1 
ATOM   2599  N  N   . SER B 2 145 ? 19.423  75.871  48.053 1   42.45  ? 126 SER L N   1 
ATOM   2600  C  CA  A SER B 2 145 ? 18.813  76.482  49.263 0.5 42.44  ? 126 SER L CA  1 
ATOM   2601  C  CA  B SER B 2 145 ? 18.815  76.482  49.264 0.5 41.71  ? 126 SER L CA  1 
ATOM   2602  C  C   . SER B 2 145 ? 18.47   75.367  50.258 1   42.7   ? 126 SER L C   1 
ATOM   2603  O  O   . SER B 2 145 ? 18.82   75.506  51.444 1   44.28  ? 126 SER L O   1 
ATOM   2604  C  CB  A SER B 2 145 ? 17.597  77.299  48.905 0.5 42.65  ? 126 SER L CB  1 
ATOM   2605  C  CB  B SER B 2 145 ? 17.596  77.3    48.917 0.5 41.13  ? 126 SER L CB  1 
ATOM   2606  O  OG  A SER B 2 145 ? 16.951  77.795  50.068 0.5 43.88  ? 126 SER L OG  1 
ATOM   2607  O  OG  B SER B 2 145 ? 17.932  78.379  48.055 0.5 40.32  ? 126 SER L OG  1 
ATOM   2608  N  N   . GLU B 2 146 ? 17.844  74.299  49.756 1   43.48  ? 127 GLU L N   1 
ATOM   2609  C  CA  . GLU B 2 146 ? 17.348  73.141  50.548 1   45.82  ? 127 GLU L CA  1 
ATOM   2610  C  C   . GLU B 2 146 ? 18.511  72.55   51.359 1   44.82  ? 127 GLU L C   1 
ATOM   2611  O  O   . GLU B 2 146 ? 18.324  72.323  52.573 1   44.74  ? 127 GLU L O   1 
ATOM   2612  C  CB  . GLU B 2 146 ? 16.679  72.12   49.62  1   49.54  ? 127 GLU L CB  1 
ATOM   2613  C  CG  . GLU B 2 146 ? 15.323  72.565  49.068 1   52.52  ? 127 GLU L CG  1 
ATOM   2614  C  CD  . GLU B 2 146 ? 15.312  73.575  47.921 1   56.19  ? 127 GLU L CD  1 
ATOM   2615  O  OE1 . GLU B 2 146 ? 16.408  73.998  47.467 1   55.62  ? 127 GLU L OE1 1 
ATOM   2616  O  OE2 . GLU B 2 146 ? 14.199  73.958  47.484 1   56.22  ? 127 GLU L OE2 1 
ATOM   2617  N  N   . GLU B 2 147 ? 19.675  72.357  50.724 1   43.98  ? 128 GLU L N   1 
ATOM   2618  C  CA  . GLU B 2 147 ? 20.895  71.77   51.349 1   42.26  ? 128 GLU L CA  1 
ATOM   2619  C  C   . GLU B 2 147 ? 21.471  72.737  52.392 1   42.02  ? 128 GLU L C   1 
ATOM   2620  O  O   . GLU B 2 147 ? 21.792  72.265  53.501 1   40.46  ? 128 GLU L O   1 
ATOM   2621  C  CB  . GLU B 2 147 ? 21.937  71.425  50.284 1   41.89  ? 128 GLU L CB  1 
ATOM   2622  C  CG  . GLU B 2 147 ? 23.049  70.526  50.795 1   41.97  ? 128 GLU L CG  1 
ATOM   2623  C  CD  . GLU B 2 147 ? 24.173  70.251  49.809 1   43.68  ? 128 GLU L CD  1 
ATOM   2624  O  OE1 . GLU B 2 147 ? 24.098  70.753  48.659 1   43.57  ? 128 GLU L OE1 1 
ATOM   2625  O  OE2 . GLU B 2 147 ? 25.122  69.525  50.191 1   42.73  ? 128 GLU L OE2 1 
ATOM   2626  N  N   . LEU B 2 148 ? 21.603  74.026  52.049 1   43.47  ? 129 LEU L N   1 
ATOM   2627  C  CA  . LEU B 2 148 ? 22.085  75.11   52.957 1   44.46  ? 129 LEU L CA  1 
ATOM   2628  C  C   . LEU B 2 148 ? 21.176  75.212  54.189 1   47.46  ? 129 LEU L C   1 
ATOM   2629  O  O   . LEU B 2 148 ? 21.718  75.441  55.287 1   50.37  ? 129 LEU L O   1 
ATOM   2630  C  CB  . LEU B 2 148 ? 22.124  76.449  52.211 1   43.05  ? 129 LEU L CB  1 
ATOM   2631  C  CG  . LEU B 2 148 ? 23.131  76.558  51.068 1   42.15  ? 129 LEU L CG  1 
ATOM   2632  C  CD1 . LEU B 2 148 ? 22.904  77.836  50.282 1   41.2   ? 129 LEU L CD1 1 
ATOM   2633  C  CD2 . LEU B 2 148 ? 24.561  76.497  51.575 1   43.24  ? 129 LEU L CD2 1 
ATOM   2634  N  N   . GLN B 2 149 ? 19.858  75.048  54.017 1   50.08  ? 130 GLN L N   1 
ATOM   2635  C  CA  . GLN B 2 149 ? 18.858  75.041  55.123 1   53.93  ? 130 GLN L CA  1 
ATOM   2636  C  C   . GLN B 2 149 ? 19.075  73.822  56.03  1   52.75  ? 130 GLN L C   1 
ATOM   2637  O  O   . GLN B 2 149 ? 18.638  73.895  57.197 1   55.12  ? 130 GLN L O   1 
ATOM   2638  C  CB  . GLN B 2 149 ? 17.422  75.063  54.589 1   59.21  ? 130 GLN L CB  1 
ATOM   2639  C  CG  . GLN B 2 149 ? 16.972  76.436  54.108 1   65.15  ? 130 GLN L CG  1 
ATOM   2640  C  CD  . GLN B 2 149 ? 15.639  76.394  53.396 1   72.67  ? 130 GLN L CD  1 
ATOM   2641  O  OE1 . GLN B 2 149 ? 14.797  75.535  53.657 1   78.38  ? 130 GLN L OE1 1 
ATOM   2642  N  NE2 . GLN B 2 149 ? 15.431  77.331  52.481 1   75.63  ? 130 GLN L NE2 1 
ATOM   2643  N  N   . ALA B 2 150 ? 19.692  72.747  55.517 1   49.97  ? 131 ALA L N   1 
ATOM   2644  C  CA  . ALA B 2 150 ? 20.078  71.531  56.279 1   49.31  ? 131 ALA L CA  1 
ATOM   2645  C  C   . ALA B 2 150 ? 21.532  71.621  56.78  1   47.76  ? 131 ALA L C   1 
ATOM   2646  O  O   . ALA B 2 150 ? 22.051  70.594  57.255 1   45.69  ? 131 ALA L O   1 
ATOM   2647  C  CB  . ALA B 2 150 ? 19.857  70.304  55.424 1   50.89  ? 131 ALA L CB  1 
ATOM   2648  N  N   . ASN B 2 151 ? 22.161  72.802  56.699 1   48.33  ? 132 ASN L N   1 
ATOM   2649  C  CA  . ASN B 2 151 ? 23.511  73.1    57.255 1   48.66  ? 132 ASN L CA  1 
ATOM   2650  C  C   . ASN B 2 151 ? 24.576  72.223  56.573 1   47.48  ? 132 ASN L C   1 
ATOM   2651  O  O   . ASN B 2 151 ? 25.536  71.809  57.256 1   48.67  ? 132 ASN L O   1 
ATOM   2652  C  CB  . ASN B 2 151 ? 23.515  72.962  58.781 1   48.58  ? 132 ASN L CB  1 
ATOM   2653  C  CG  . ASN B 2 151 ? 24.751  73.554  59.427 1   48.02  ? 132 ASN L CG  1 
ATOM   2654  O  OD1 . ASN B 2 151 ? 25.167  74.659  59.084 1   49.14  ? 132 ASN L OD1 1 
ATOM   2655  N  ND2 . ASN B 2 151 ? 25.353  72.826  60.353 1   47.96  ? 132 ASN L ND2 1 
ATOM   2656  N  N   . LYS B 2 152 ? 24.407  71.948  55.276 1   45.04  ? 133 LYS L N   1 
ATOM   2657  C  CA  . LYS B 2 152 ? 25.413  71.288  54.405 1   44.88  ? 133 LYS L CA  1 
ATOM   2658  C  C   . LYS B 2 152 ? 25.554  72.128  53.135 1   41.87  ? 133 LYS L C   1 
ATOM   2659  O  O   . LYS B 2 152 ? 24.755  73.046  52.952 1   42.32  ? 133 LYS L O   1 
ATOM   2660  C  CB  . LYS B 2 152 ? 24.999  69.85   54.075 1   47.77  ? 133 LYS L CB  1 
ATOM   2661  C  CG  . LYS B 2 152 ? 24.802  68.926  55.27  1   51.15  ? 133 LYS L CG  1 
ATOM   2662  C  CD  . LYS B 2 152 ? 26.1    68.513  55.936 1   55.54  ? 133 LYS L CD  1 
ATOM   2663  C  CE  . LYS B 2 152 ? 25.963  68.201  57.413 1   58.33  ? 133 LYS L CE  1 
ATOM   2664  N  NZ  . LYS B 2 152 ? 27.289  68.098  58.071 1   59.49  ? 133 LYS L NZ  1 
ATOM   2665  N  N   . ALA B 2 153 ? 26.539  71.826  52.293 1   41.02  ? 134 ALA L N   1 
ATOM   2666  C  CA  . ALA B 2 153 ? 26.798  72.56   51.033 1   38.37  ? 134 ALA L CA  1 
ATOM   2667  C  C   . ALA B 2 153 ? 27.677  71.71   50.114 1   36.67  ? 134 ALA L C   1 
ATOM   2668  O  O   . ALA B 2 153 ? 28.784  71.35   50.537 1   36.03  ? 134 ALA L O   1 
ATOM   2669  C  CB  . ALA B 2 153 ? 27.433  73.897  51.329 1   36.54  ? 134 ALA L CB  1 
ATOM   2670  N  N   . THR B 2 154 ? 27.187  71.416  48.908 1   37.26  ? 135 THR L N   1 
ATOM   2671  C  CA  . THR B 2 154 ? 27.868  70.585  47.882 1   36.89  ? 135 THR L CA  1 
ATOM   2672  C  C   . THR B 2 154 ? 27.842  71.33   46.547 1   37.37  ? 135 THR L C   1 
ATOM   2673  O  O   . THR B 2 154 ? 26.728  71.68   46.09  1   39.06  ? 135 THR L O   1 
ATOM   2674  C  CB  . THR B 2 154 ? 27.204  69.21   47.744 1   37.73  ? 135 THR L CB  1 
ATOM   2675  O  OG1 . THR B 2 154 ? 27.141  68.595  49.033 1   37.37  ? 135 THR L OG1 1 
ATOM   2676  C  CG2 . THR B 2 154 ? 27.944  68.3    46.786 1   38.69  ? 135 THR L CG2 1 
ATOM   2677  N  N   . LEU B 2 155 ? 29.022  71.565  45.965 1   36.85  ? 136 LEU L N   1 
ATOM   2678  C  CA  . LEU B 2 155 ? 29.194  71.993  44.555 1   36.12  ? 136 LEU L CA  1 
ATOM   2679  C  C   . LEU B 2 155 ? 29.307  70.725  43.712 1   36.39  ? 136 LEU L C   1 
ATOM   2680  O  O   . LEU B 2 155 ? 30.088  69.839  44.091 1   34.42  ? 136 LEU L O   1 
ATOM   2681  C  CB  . LEU B 2 155 ? 30.442  72.867  44.404 1   38.41  ? 136 LEU L CB  1 
ATOM   2682  C  CG  . LEU B 2 155 ? 30.298  74.319  44.847 1   39.46  ? 136 LEU L CG  1 
ATOM   2683  C  CD1 . LEU B 2 155 ? 29.882  74.417  46.304 1   41.13  ? 136 LEU L CD1 1 
ATOM   2684  C  CD2 . LEU B 2 155 ? 31.595  75.072  44.629 1   39.12  ? 136 LEU L CD2 1 
ATOM   2685  N  N   . VAL B 2 156 ? 28.533  70.641  42.631 1   37.39  ? 137 VAL L N   1 
ATOM   2686  C  CA  . VAL B 2 156 ? 28.419  69.425  41.778 1   37.02  ? 137 VAL L CA  1 
ATOM   2687  C  C   . VAL B 2 156 ? 28.916  69.796  40.379 1   36.85  ? 137 VAL L C   1 
ATOM   2688  O  O   . VAL B 2 156 ? 28.263  70.626  39.719 1   36.02  ? 137 VAL L O   1 
ATOM   2689  C  CB  . VAL B 2 156 ? 26.982  68.871  41.773 1   37.54  ? 137 VAL L CB  1 
ATOM   2690  C  CG1 . VAL B 2 156 ? 26.881  67.584  40.965 1   37.66  ? 137 VAL L CG1 1 
ATOM   2691  C  CG2 . VAL B 2 156 ? 26.452  68.658  43.189 1   36.79  ? 137 VAL L CG2 1 
ATOM   2692  N  N   . CYS B 2 157 ? 30.048  69.213  39.982 1   36.18  ? 138 CYS L N   1 
ATOM   2693  C  CA  . CYS B 2 157 ? 30.706  69.387  38.665 1   37.76  ? 138 CYS L CA  1 
ATOM   2694  C  C   . CYS B 2 157 ? 30.497  68.114  37.838 1   38.27  ? 138 CYS L C   1 
ATOM   2695  O  O   . CYS B 2 157 ? 31.074  67.07   38.21  1   36.96  ? 138 CYS L O   1 
ATOM   2696  C  CB  . CYS B 2 157 ? 32.185  69.68   38.859 1   38.94  ? 138 CYS L CB  1 
ATOM   2697  S  SG  . CYS B 2 157 ? 32.995  70.338  37.381 1   41.35  ? 138 CYS L SG  1 
ATOM   2698  N  N   . LEU B 2 158 ? 29.678  68.204  36.785 1   38.57  ? 139 LEU L N   1 
ATOM   2699  C  CA  . LEU B 2 158 ? 29.23   67.065  35.945 1   39.39  ? 139 LEU L CA  1 
ATOM   2700  C  C   . LEU B 2 158 ? 29.93   67.155  34.589 1   40.75  ? 139 LEU L C   1 
ATOM   2701  O  O   . LEU B 2 158 ? 29.799  68.198  33.914 1   40.79  ? 139 LEU L O   1 
ATOM   2702  C  CB  . LEU B 2 158 ? 27.704  67.108  35.807 1   42.02  ? 139 LEU L CB  1 
ATOM   2703  C  CG  . LEU B 2 158 ? 26.925  67.022  37.122 1   42.91  ? 139 LEU L CG  1 
ATOM   2704  C  CD1 . LEU B 2 158 ? 25.444  67.261  36.892 1   43.87  ? 139 LEU L CD1 1 
ATOM   2705  C  CD2 . LEU B 2 158 ? 27.14   65.681  37.81  1   43.01  ? 139 LEU L CD2 1 
ATOM   2706  N  N   . ILE B 2 159 ? 30.659  66.094  34.237 1   40.89  ? 140 ILE L N   1 
ATOM   2707  C  CA  . ILE B 2 159 ? 31.595  66.025  33.081 1   39.94  ? 140 ILE L CA  1 
ATOM   2708  C  C   . ILE B 2 159 ? 31.141  64.861  32.199 1   40.99  ? 140 ILE L C   1 
ATOM   2709  O  O   . ILE B 2 159 ? 31.15   63.721  32.687 1   40.42  ? 140 ILE L O   1 
ATOM   2710  C  CB  . ILE B 2 159 ? 33.046  65.86   33.569 1   40.33  ? 140 ILE L CB  1 
ATOM   2711  C  CG1 . ILE B 2 159 ? 33.34   66.747  34.784 1   41.55  ? 140 ILE L CG1 1 
ATOM   2712  C  CG2 . ILE B 2 159 ? 34.016  66.115  32.429 1   39.95  ? 140 ILE L CG2 1 
ATOM   2713  C  CD1 . ILE B 2 159 ? 34.655  66.457  35.467 1   43.59  ? 140 ILE L CD1 1 
ATOM   2714  N  N   . SER B 2 160 ? 30.74   65.149  30.96  1   41.73  ? 141 SER L N   1 
ATOM   2715  C  CA  . SER B 2 160 ? 30.136  64.172  30.021 1   42.66  ? 141 SER L CA  1 
ATOM   2716  C  C   . SER B 2 160 ? 30.718  64.329  28.614 1   43.85  ? 141 SER L C   1 
ATOM   2717  O  O   . SER B 2 160 ? 31.284  65.4    28.303 1   42.06  ? 141 SER L O   1 
ATOM   2718  C  CB  . SER B 2 160 ? 28.642  64.318  30.001 1   42.91  ? 141 SER L CB  1 
ATOM   2719  O  OG  . SER B 2 160 ? 28.275  65.628  29.604 1   43.05  ? 141 SER L OG  1 
ATOM   2720  N  N   . ASP B 2 161 ? 30.57   63.269  27.815 1   46.23  ? 142 ASP L N   1 
ATOM   2721  C  CA  . ASP B 2 161 ? 30.749  63.242  26.341 1   47.3   ? 142 ASP L CA  1 
ATOM   2722  C  C   . ASP B 2 161 ? 32.202  63.581  25.998 1   45.24  ? 142 ASP L C   1 
ATOM   2723  O  O   . ASP B 2 161 ? 32.407  64.358  25.037 1   48.11  ? 142 ASP L O   1 
ATOM   2724  C  CB  . ASP B 2 161 ? 29.748  64.177  25.651 1   50.5   ? 142 ASP L CB  1 
ATOM   2725  C  CG  . ASP B 2 161 ? 28.291  63.884  25.972 1   55.59  ? 142 ASP L CG  1 
ATOM   2726  O  OD1 . ASP B 2 161 ? 27.932  62.684  26.057 1   56.27  ? 142 ASP L OD1 1 
ATOM   2727  O  OD2 . ASP B 2 161 ? 27.519  64.861  26.129 1   60.58  ? 142 ASP L OD2 1 
ATOM   2728  N  N   . PHE B 2 162 ? 33.169  63.027  26.74  1   41.45  ? 143 PHE L N   1 
ATOM   2729  C  CA  . PHE B 2 162 ? 34.618  63.21   26.458 1   40.55  ? 143 PHE L CA  1 
ATOM   2730  C  C   . PHE B 2 162 ? 35.251  61.883  26.031 1   41.62  ? 143 PHE L C   1 
ATOM   2731  O  O   . PHE B 2 162 ? 34.8    60.803  26.464 1   40.58  ? 143 PHE L O   1 
ATOM   2732  C  CB  . PHE B 2 162 ? 35.37   63.864  27.62  1   39.17  ? 143 PHE L CB  1 
ATOM   2733  C  CG  . PHE B 2 162 ? 35.358  63.159  28.953 1   39.08  ? 143 PHE L CG  1 
ATOM   2734  C  CD1 . PHE B 2 162 ? 36.335  62.227  29.275 1   39.14  ? 143 PHE L CD1 1 
ATOM   2735  C  CD2 . PHE B 2 162 ? 34.416  63.487  29.92  1   39.48  ? 143 PHE L CD2 1 
ATOM   2736  C  CE1 . PHE B 2 162 ? 36.346  61.61   30.519 1   38.85  ? 143 PHE L CE1 1 
ATOM   2737  C  CE2 . PHE B 2 162 ? 34.428  62.872  31.165 1   38.73  ? 143 PHE L CE2 1 
ATOM   2738  C  CZ  . PHE B 2 162 ? 35.394  61.938  31.463 1   39.2   ? 143 PHE L CZ  1 
ATOM   2739  N  N   . TYR B 2 163 ? 36.269  61.993  25.173 1   41.88  ? 144 TYR L N   1 
ATOM   2740  C  CA  . TYR B 2 163 ? 37.097  60.876  24.655 1   41.18  ? 144 TYR L CA  1 
ATOM   2741  C  C   . TYR B 2 163 ? 38.499  61.401  24.347 1   42.54  ? 144 TYR L C   1 
ATOM   2742  O  O   . TYR B 2 163 ? 38.614  62.488  23.785 1   41.54  ? 144 TYR L O   1 
ATOM   2743  C  CB  . TYR B 2 163 ? 36.479  60.277  23.391 1   40.92  ? 144 TYR L CB  1 
ATOM   2744  C  CG  . TYR B 2 163 ? 37.019  58.913  23.057 1   40.08  ? 144 TYR L CG  1 
ATOM   2745  C  CD1 . TYR B 2 163 ? 38.217  58.758  22.375 1   39.19  ? 144 TYR L CD1 1 
ATOM   2746  C  CD2 . TYR B 2 163 ? 36.356  57.771  23.477 1   40.6   ? 144 TYR L CD2 1 
ATOM   2747  C  CE1 . TYR B 2 163 ? 38.735  57.501  22.105 1   40.7   ? 144 TYR L CE1 1 
ATOM   2748  C  CE2 . TYR B 2 163 ? 36.856  56.507  23.208 1   41.65  ? 144 TYR L CE2 1 
ATOM   2749  C  CZ  . TYR B 2 163 ? 38.05   56.373  22.522 1   41.36  ? 144 TYR L CZ  1 
ATOM   2750  O  OH  . TYR B 2 163 ? 38.529  55.126  22.258 1   43.48  ? 144 TYR L OH  1 
ATOM   2751  N  N   . PRO B 2 164 ? 39.6    60.676  24.673 1   42.07  ? 145 PRO L N   1 
ATOM   2752  C  CA  . PRO B 2 164 ? 39.557  59.451  25.481 1   42.65  ? 145 PRO L CA  1 
ATOM   2753  C  C   . PRO B 2 164 ? 39.203  59.708  26.956 1   41.38  ? 145 PRO L C   1 
ATOM   2754  O  O   . PRO B 2 164 ? 39.084  60.856  27.339 1   42.32  ? 145 PRO L O   1 
ATOM   2755  C  CB  . PRO B 2 164 ? 40.972  58.865  25.33  1   42.34  ? 145 PRO L CB  1 
ATOM   2756  C  CG  . PRO B 2 164 ? 41.843  60.062  25.032 1   42.45  ? 145 PRO L CG  1 
ATOM   2757  C  CD  . PRO B 2 164 ? 40.964  60.99   24.22  1   41.73  ? 145 PRO L CD  1 
ATOM   2758  N  N   . GLY B 2 165 ? 39.033  58.63   27.731 1   41.64  ? 146 GLY L N   1 
ATOM   2759  C  CA  . GLY B 2 165 ? 38.447  58.641  29.09  1   41.5   ? 146 GLY L CA  1 
ATOM   2760  C  C   . GLY B 2 165 ? 39.467  58.95   30.174 1   40.49  ? 146 GLY L C   1 
ATOM   2761  O  O   . GLY B 2 165 ? 39.674  58.095  31.049 1   41.31  ? 146 GLY L O   1 
ATOM   2762  N  N   . ALA B 2 166 ? 40.082  60.131  30.121 1   40.64  ? 147 ALA L N   1 
ATOM   2763  C  CA  . ALA B 2 166 ? 40.99   60.666  31.161 1   40.48  ? 147 ALA L CA  1 
ATOM   2764  C  C   . ALA B 2 166 ? 40.759  62.175  31.303 1   40.19  ? 147 ALA L C   1 
ATOM   2765  O  O   . ALA B 2 166 ? 40.765  62.877  30.28  1   39.67  ? 147 ALA L O   1 
ATOM   2766  C  CB  . ALA B 2 166 ? 42.424  60.355  30.81  1   39.71  ? 147 ALA L CB  1 
ATOM   2767  N  N   . VAL B 2 167 ? 40.54   62.638  32.534 1   41.56  ? 148 VAL L N   1 
ATOM   2768  C  CA  . VAL B 2 167 ? 40.445  64.079  32.905 1   41.53  ? 148 VAL L CA  1 
ATOM   2769  C  C   . VAL B 2 167 ? 41.108  64.263  34.269 1   44.58  ? 148 VAL L C   1 
ATOM   2770  O  O   . VAL B 2 167 ? 41.093  63.302  35.067 1   48     ? 148 VAL L O   1 
ATOM   2771  C  CB  . VAL B 2 167 ? 38.987  64.57   32.94  1   41.28  ? 148 VAL L CB  1 
ATOM   2772  C  CG1 . VAL B 2 167 ? 38.429  64.79   31.545 1   41.53  ? 148 VAL L CG1 1 
ATOM   2773  C  CG2 . VAL B 2 167 ? 38.084  63.645  33.741 1   41.76  ? 148 VAL L CG2 1 
ATOM   2774  N  N   . THR B 2 168 ? 41.657  65.451  34.524 1   45.62  ? 149 THR L N   1 
ATOM   2775  C  CA  . THR B 2 168 ? 42.041  65.917  35.88  1   46.31  ? 149 THR L CA  1 
ATOM   2776  C  C   . THR B 2 168 ? 41.079  67.047  36.258 1   44.37  ? 149 THR L C   1 
ATOM   2777  O  O   . THR B 2 168 ? 40.79   67.895  35.387 1   43.66  ? 149 THR L O   1 
ATOM   2778  C  CB  . THR B 2 168 ? 43.526  66.298  35.964 1   49.05  ? 149 THR L CB  1 
ATOM   2779  O  OG1 . THR B 2 168 ? 43.717  67.605  35.419 1   53.56  ? 149 THR L OG1 1 
ATOM   2780  C  CG2 . THR B 2 168 ? 44.432  65.313  35.255 1   51.08  ? 149 THR L CG2 1 
ATOM   2781  N  N   . VAL B 2 169 ? 40.581  67.021  37.495 1   42.45  ? 150 VAL L N   1 
ATOM   2782  C  CA  . VAL B 2 169 ? 39.671  68.051  38.066 1   41.04  ? 150 VAL L CA  1 
ATOM   2783  C  C   . VAL B 2 169 ? 40.45   68.808  39.142 1   41.58  ? 150 VAL L C   1 
ATOM   2784  O  O   . VAL B 2 169 ? 40.944  68.154  40.092 1   41.09  ? 150 VAL L O   1 
ATOM   2785  C  CB  . VAL B 2 169 ? 38.379  67.437  38.634 1   41.69  ? 150 VAL L CB  1 
ATOM   2786  C  CG1 . VAL B 2 169 ? 37.409  68.52   39.089 1   41.69  ? 150 VAL L CG1 1 
ATOM   2787  C  CG2 . VAL B 2 169 ? 37.704  66.502  37.639 1   41.49  ? 150 VAL L CG2 1 
ATOM   2788  N  N   . ALA B 2 170 ? 40.561  70.129  38.973 1   40.37  ? 151 ALA L N   1 
ATOM   2789  C  CA  . ALA B 2 170 ? 41.07   71.086  39.978 1   40.05  ? 151 ALA L CA  1 
ATOM   2790  C  C   . ALA B 2 170 ? 39.917  71.994  40.411 1   40.09  ? 151 ALA L C   1 
ATOM   2791  O  O   . ALA B 2 170 ? 39.169  72.461  39.528 1   40.57  ? 151 ALA L O   1 
ATOM   2792  C  CB  . ALA B 2 170 ? 42.212  71.884  39.407 1   39.85  ? 151 ALA L CB  1 
ATOM   2793  N  N   . TRP B 2 171 ? 39.786  72.219  41.72  1   39.17  ? 152 TRP L N   1 
ATOM   2794  C  CA  . TRP B 2 171 ? 38.813  73.157  42.336 1   39.07  ? 152 TRP L CA  1 
ATOM   2795  C  C   . TRP B 2 171 ? 39.535  74.422  42.798 1   38.48  ? 152 TRP L C   1 
ATOM   2796  O  O   . TRP B 2 171 ? 40.715  74.324  43.185 1   39.16  ? 152 TRP L O   1 
ATOM   2797  C  CB  . TRP B 2 171 ? 38.089  72.477  43.499 1   39.4   ? 152 TRP L CB  1 
ATOM   2798  C  CG  . TRP B 2 171 ? 37.108  71.447  43.049 1   38.5   ? 152 TRP L CG  1 
ATOM   2799  C  CD1 . TRP B 2 171 ? 37.355  70.132  42.797 1   38.54  ? 152 TRP L CD1 1 
ATOM   2800  C  CD2 . TRP B 2 171 ? 35.715  71.659  42.779 1   39.24  ? 152 TRP L CD2 1 
ATOM   2801  N  NE1 . TRP B 2 171 ? 36.205  69.507  42.4   1   39.51  ? 152 TRP L NE1 1 
ATOM   2802  C  CE2 . TRP B 2 171 ? 35.183  70.416  42.378 1   39.71  ? 152 TRP L CE2 1 
ATOM   2803  C  CE3 . TRP B 2 171 ? 34.868  72.772  42.837 1   39.7   ? 152 TRP L CE3 1 
ATOM   2804  C  CZ2 . TRP B 2 171 ? 33.84   70.259  42.04  1   41.1   ? 152 TRP L CZ2 1 
ATOM   2805  C  CZ3 . TRP B 2 171 ? 33.539  72.615  42.509 1   40.08  ? 152 TRP L CZ3 1 
ATOM   2806  C  CH2 . TRP B 2 171 ? 33.033  71.374  42.12  1   40.77  ? 152 TRP L CH2 1 
ATOM   2807  N  N   . LYS B 2 172 ? 38.839  75.558  42.777 1   38.99  ? 153 LYS L N   1 
ATOM   2808  C  CA  . LYS B 2 172 ? 39.357  76.849  43.296 1   42.15  ? 153 LYS L CA  1 
ATOM   2809  C  C   . LYS B 2 172 ? 38.298  77.494  44.192 1   42.64  ? 153 LYS L C   1 
ATOM   2810  O  O   . LYS B 2 172 ? 37.096  77.339  43.908 1   41.34  ? 153 LYS L O   1 
ATOM   2811  C  CB  . LYS B 2 172 ? 39.748  77.786  42.151 1   43.82  ? 153 LYS L CB  1 
ATOM   2812  C  CG  . LYS B 2 172 ? 41.033  77.423  41.419 1   47.39  ? 153 LYS L CG  1 
ATOM   2813  C  CD  . LYS B 2 172 ? 41.132  78.026  40.03  1   52.5   ? 153 LYS L CD  1 
ATOM   2814  C  CE  . LYS B 2 172 ? 41.245  79.54   40.022 1   56.42  ? 153 LYS L CE  1 
ATOM   2815  N  NZ  . LYS B 2 172 ? 40.651  80.14   38.801 1   57.32  ? 153 LYS L NZ  1 
ATOM   2816  N  N   . ALA B 2 173 ? 38.759  78.148  45.259 1   44.68  ? 154 ALA L N   1 
ATOM   2817  C  CA  . ALA B 2 173 ? 38.009  79.12   46.081 1   46.34  ? 154 ALA L CA  1 
ATOM   2818  C  C   . ALA B 2 173 ? 38.677  80.48   45.865 1   48.31  ? 154 ALA L C   1 
ATOM   2819  O  O   . ALA B 2 173 ? 39.863  80.615  46.238 1   46.9   ? 154 ALA L O   1 
ATOM   2820  C  CB  . ALA B 2 173 ? 38.018  78.701  47.53  1   45.24  ? 154 ALA L CB  1 
ATOM   2821  N  N   . ASP B 2 174 ? 37.964  81.416  45.23  1   51.88  ? 155 ASP L N   1 
ATOM   2822  C  CA  . ASP B 2 174 ? 38.532  82.667  44.662 1   54.03  ? 155 ASP L CA  1 
ATOM   2823  C  C   . ASP B 2 174 ? 39.609  82.252  43.645 1   55.09  ? 155 ASP L C   1 
ATOM   2824  O  O   . ASP B 2 174 ? 39.27   81.467  42.736 1   54.05  ? 155 ASP L O   1 
ATOM   2825  C  CB  . ASP B 2 174 ? 38.984  83.605  45.788 1   54.44  ? 155 ASP L CB  1 
ATOM   2826  C  CG  . ASP B 2 174 ? 37.889  83.916  46.795 1   53.87  ? 155 ASP L CG  1 
ATOM   2827  O  OD1 . ASP B 2 174 ? 36.72   84.042  46.366 1   54.63  ? 155 ASP L OD1 1 
ATOM   2828  O  OD2 . ASP B 2 174 ? 38.212  84.034  47.999 1   51.84  ? 155 ASP L OD2 1 
ATOM   2829  N  N   . SER B 2 175 ? 40.853  82.715  43.798 1   56.62  ? 156 SER L N   1 
ATOM   2830  C  CA  . SER B 2 175 ? 42.002  82.349  42.925 1   60.39  ? 156 SER L CA  1 
ATOM   2831  C  C   . SER B 2 175 ? 42.78   81.159  43.516 1   58.25  ? 156 SER L C   1 
ATOM   2832  O  O   . SER B 2 175 ? 43.631  80.607  42.798 1   60.19  ? 156 SER L O   1 
ATOM   2833  C  CB  . SER B 2 175 ? 42.891  83.551  42.699 1   62     ? 156 SER L CB  1 
ATOM   2834  O  OG  . SER B 2 175 ? 43.027  84.31   43.894 1   65.44  ? 156 SER L OG  1 
ATOM   2835  N  N   . SER B 2 176 ? 42.494  80.767  44.763 1   56.27  ? 157 SER L N   1 
ATOM   2836  C  CA  . SER B 2 176 ? 43.285  79.789  45.555 1   55.55  ? 157 SER L CA  1 
ATOM   2837  C  C   . SER B 2 176 ? 42.822  78.368  45.244 1   52.86  ? 157 SER L C   1 
ATOM   2838  O  O   . SER B 2 176 ? 41.624  78.098  45.304 1   53.26  ? 157 SER L O   1 
ATOM   2839  C  CB  . SER B 2 176 ? 43.163  80.073  47.032 1   59.66  ? 157 SER L CB  1 
ATOM   2840  O  OG  . SER B 2 176 ? 43.656  81.366  47.343 1   62.83  ? 157 SER L OG  1 
ATOM   2841  N  N   . PRO B 2 177 ? 43.735  77.42   44.915 1   47.35  ? 158 PRO L N   1 
ATOM   2842  C  CA  . PRO B 2 177 ? 43.375  76.008  44.799 1   45.69  ? 158 PRO L CA  1 
ATOM   2843  C  C   . PRO B 2 177 ? 42.771  75.434  46.087 1   43.6   ? 158 PRO L C   1 
ATOM   2844  O  O   . PRO B 2 177 ? 43.212  75.821  47.148 1   43.63  ? 158 PRO L O   1 
ATOM   2845  C  CB  . PRO B 2 177 ? 44.708  75.296  44.518 1   46.02  ? 158 PRO L CB  1 
ATOM   2846  C  CG  . PRO B 2 177 ? 45.579  76.363  43.909 1   46.56  ? 158 PRO L CG  1 
ATOM   2847  C  CD  . PRO B 2 177 ? 45.151  77.648  44.585 1   47.91  ? 158 PRO L CD  1 
ATOM   2848  N  N   . VAL B 2 178 ? 41.789  74.539  45.946 1   41.47  ? 159 VAL L N   1 
ATOM   2849  C  CA  . VAL B 2 178 ? 41.192  73.726  47.046 1   40.6   ? 159 VAL L CA  1 
ATOM   2850  C  C   . VAL B 2 178 ? 41.275  72.259  46.623 1   38.86  ? 159 VAL L C   1 
ATOM   2851  O  O   . VAL B 2 178 ? 40.91   71.966  45.473 1   39.92  ? 159 VAL L O   1 
ATOM   2852  C  CB  . VAL B 2 178 ? 39.738  74.142  47.343 1   41.32  ? 159 VAL L CB  1 
ATOM   2853  C  CG1 . VAL B 2 178 ? 39.15   73.405  48.542 1   40.01  ? 159 VAL L CG1 1 
ATOM   2854  C  CG2 . VAL B 2 178 ? 39.623  75.641  47.544 1   42.15  ? 159 VAL L CG2 1 
ATOM   2855  N  N   . LYS B 2 179 ? 41.763  71.393  47.513 1   38.7   ? 160 LYS L N   1 
ATOM   2856  C  CA  . LYS B 2 179 ? 41.857  69.922  47.302 1   39.58  ? 160 LYS L CA  1 
ATOM   2857  C  C   . LYS B 2 179 ? 41.04   69.171  48.361 1   38.85  ? 160 LYS L C   1 
ATOM   2858  O  O   . LYS B 2 179 ? 40.58   68.06   48.049 1   39.45  ? 160 LYS L O   1 
ATOM   2859  C  CB  . LYS B 2 179 ? 43.326  69.488  47.309 1   40.37  ? 160 LYS L CB  1 
ATOM   2860  C  CG  . LYS B 2 179 ? 44.23   70.286  46.377 1   41.24  ? 160 LYS L CG  1 
ATOM   2861  C  CD  . LYS B 2 179 ? 45.421  69.516  45.85  1   43     ? 160 LYS L CD  1 
ATOM   2862  C  CE  . LYS B 2 179 ? 46.305  70.344  44.938 1   44.01  ? 160 LYS L CE  1 
ATOM   2863  N  NZ  . LYS B 2 179 ? 47.481  69.587  44.472 0   42.45  ? 160 LYS L NZ  1 
ATOM   2864  N  N   . ALA B 2 180 ? 40.878  69.737  49.562 1   39.46  ? 161 ALA L N   1 
ATOM   2865  C  CA  . ALA B 2 180 ? 40.124  69.143  50.691 1   39.84  ? 161 ALA L CA  1 
ATOM   2866  C  C   . ALA B 2 180 ? 38.628  69.195  50.388 1   39.87  ? 161 ALA L C   1 
ATOM   2867  O  O   . ALA B 2 180 ? 38.163  70.25   49.923 1   40.85  ? 161 ALA L O   1 
ATOM   2868  C  CB  . ALA B 2 180 ? 40.424  69.882  51.969 1   41.58  ? 161 ALA L CB  1 
ATOM   2869  N  N   . GLY B 2 181 ? 37.911  68.101  50.663 1   39.04  ? 162 GLY L N   1 
ATOM   2870  C  CA  . GLY B 2 181 ? 36.466  67.972  50.399 1   38.44  ? 162 GLY L CA  1 
ATOM   2871  C  C   . GLY B 2 181 ? 36.16   67.659  48.942 1   37.81  ? 162 GLY L C   1 
ATOM   2872  O  O   . GLY B 2 181 ? 34.983  67.757  48.569 1   37.21  ? 162 GLY L O   1 
ATOM   2873  N  N   . VAL B 2 182 ? 37.167  67.276  48.15  1   38.33  ? 163 VAL L N   1 
ATOM   2874  C  CA  . VAL B 2 182 ? 37.015  66.892  46.717 1   39.12  ? 163 VAL L CA  1 
ATOM   2875  C  C   . VAL B 2 182 ? 36.836  65.371  46.649 1   41.53  ? 163 VAL L C   1 
ATOM   2876  O  O   . VAL B 2 182 ? 37.696  64.649  47.188 1   44.07  ? 163 VAL L O   1 
ATOM   2877  C  CB  . VAL B 2 182 ? 38.208  67.369  45.868 1   38.38  ? 163 VAL L CB  1 
ATOM   2878  C  CG1 . VAL B 2 182 ? 38.116  66.889  44.426 1   39.27  ? 163 VAL L CG1 1 
ATOM   2879  C  CG2 . VAL B 2 182 ? 38.344  68.883  45.904 1   38.55  ? 163 VAL L CG2 1 
ATOM   2880  N  N   . GLU B 2 183 ? 35.748  64.916  46.025 1   41.6   ? 164 GLU L N   1 
ATOM   2881  C  CA  . GLU B 2 183 ? 35.485  63.491  45.704 1   44.93  ? 164 GLU L CA  1 
ATOM   2882  C  C   . GLU B 2 183 ? 35.217  63.421  44.196 1   43.83  ? 164 GLU L C   1 
ATOM   2883  O  O   . GLU B 2 183 ? 34.201  63.997  43.752 1   43.43  ? 164 GLU L O   1 
ATOM   2884  C  CB  . GLU B 2 183 ? 34.302  62.957  46.521 1   49.64  ? 164 GLU L CB  1 
ATOM   2885  C  CG  . GLU B 2 183 ? 34.404  63.187  48.025 1   53.7   ? 164 GLU L CG  1 
ATOM   2886  C  CD  . GLU B 2 183 ? 35.293  62.231  48.81  1   57.22  ? 164 GLU L CD  1 
ATOM   2887  O  OE1 . GLU B 2 183 ? 35.929  61.348  48.19  1   57.83  ? 164 GLU L OE1 1 
ATOM   2888  O  OE2 . GLU B 2 183 ? 35.336  62.366  50.055 1   60.53  ? 164 GLU L OE2 1 
ATOM   2889  N  N   . THR B 2 184 ? 36.115  62.794  43.432 1   41.12  ? 165 THR L N   1 
ATOM   2890  C  CA  . THR B 2 184 ? 36.012  62.664  41.952 1   39.06  ? 165 THR L CA  1 
ATOM   2891  C  C   . THR B 2 184 ? 35.895  61.182  41.59  1   37.02  ? 165 THR L C   1 
ATOM   2892  O  O   . THR B 2 184 ? 36.632  60.368  42.167 1   35.44  ? 165 THR L O   1 
ATOM   2893  C  CB  . THR B 2 184 ? 37.19   63.342  41.24  1   37.27  ? 165 THR L CB  1 
ATOM   2894  O  OG1 . THR B 2 184 ? 37.297  64.673  41.739 1   35.97  ? 165 THR L OG1 1 
ATOM   2895  C  CG2 . THR B 2 184 ? 37.027  63.394  39.738 1   37.28  ? 165 THR L CG2 1 
ATOM   2896  N  N   . THR B 2 185 ? 34.983  60.859  40.675 1   36.66  ? 166 THR L N   1 
ATOM   2897  C  CA  . THR B 2 185 ? 34.776  59.49   40.142 1   38.24  ? 166 THR L CA  1 
ATOM   2898  C  C   . THR B 2 185 ? 35.825  59.2    39.066 1   41.29  ? 166 THR L C   1 
ATOM   2899  O  O   . THR B 2 185 ? 36.253  60.151  38.367 1   43.51  ? 166 THR L O   1 
ATOM   2900  C  CB  . THR B 2 185 ? 33.373  59.328  39.55  1   35.79  ? 166 THR L CB  1 
ATOM   2901  O  OG1 . THR B 2 185 ? 33.29   60.25   38.465 1   35.02  ? 166 THR L OG1 1 
ATOM   2902  C  CG2 . THR B 2 185 ? 32.271  59.567  40.559 1   34.83  ? 166 THR L CG2 1 
ATOM   2903  N  N   . THR B 2 186 ? 36.205  57.931  38.925 1   43.21  ? 167 THR L N   1 
ATOM   2904  C  CA  . THR B 2 186 ? 36.958  57.425  37.749 1   45.5   ? 167 THR L CA  1 
ATOM   2905  C  C   . THR B 2 186 ? 36.033  57.553  36.543 1   45.17  ? 167 THR L C   1 
ATOM   2906  O  O   . THR B 2 186 ? 34.84   57.292  36.669 1   45.71  ? 167 THR L O   1 
ATOM   2907  C  CB  . THR B 2 186 ? 37.431  55.979  37.947 1   46.78  ? 167 THR L CB  1 
ATOM   2908  O  OG1 . THR B 2 186 ? 36.271  55.172  38.152 1   51.17  ? 167 THR L OG1 1 
ATOM   2909  C  CG2 . THR B 2 186 ? 38.385  55.816  39.11  1   46.61  ? 167 THR L CG2 1 
ATOM   2910  N  N   . PRO B 2 187 ? 36.522  57.973  35.351 1   47.55  ? 168 PRO L N   1 
ATOM   2911  C  CA  . PRO B 2 187 ? 35.662  58.073  34.173 1   46.29  ? 168 PRO L CA  1 
ATOM   2912  C  C   . PRO B 2 187 ? 35.014  56.719  33.853 1   45.14  ? 168 PRO L C   1 
ATOM   2913  O  O   . PRO B 2 187 ? 35.626  55.699  34.113 1   45.91  ? 168 PRO L O   1 
ATOM   2914  C  CB  . PRO B 2 187 ? 36.58   58.549  33.038 1   46.3   ? 168 PRO L CB  1 
ATOM   2915  C  CG  . PRO B 2 187 ? 37.991  58.338  33.558 1   48.59  ? 168 PRO L CG  1 
ATOM   2916  C  CD  . PRO B 2 187 ? 37.908  58.375  35.068 1   48.13  ? 168 PRO L CD  1 
ATOM   2917  N  N   . SER B 2 188 ? 33.785  56.753  33.339 1   43.41  ? 169 SER L N   1 
ATOM   2918  C  CA  . SER B 2 188 ? 32.944  55.566  33.05  1   45.31  ? 169 SER L CA  1 
ATOM   2919  C  C   . SER B 2 188 ? 32.333  55.709  31.657 1   44.79  ? 169 SER L C   1 
ATOM   2920  O  O   . SER B 2 188 ? 31.996  56.852  31.278 1   42.75  ? 169 SER L O   1 
ATOM   2921  C  CB  . SER B 2 188 ? 31.884  55.396  34.103 1   47.51  ? 169 SER L CB  1 
ATOM   2922  O  OG  . SER B 2 188 ? 31.188  56.619  34.299 1   51.98  ? 169 SER L OG  1 
ATOM   2923  N  N   . LYS B 2 189 ? 32.183  54.58   30.958 1   44.66  ? 170 LYS L N   1 
ATOM   2924  C  CA  . LYS B 2 189 ? 31.759  54.489  29.538 1   46.87  ? 170 LYS L CA  1 
ATOM   2925  C  C   . LYS B 2 189 ? 30.267  54.819  29.433 1   46.48  ? 170 LYS L C   1 
ATOM   2926  O  O   . LYS B 2 189 ? 29.465  54.124  30.08  1   46.79  ? 170 LYS L O   1 
ATOM   2927  C  CB  . LYS B 2 189 ? 32.057  53.082  29.007 1   49.69  ? 170 LYS L CB  1 
ATOM   2928  C  CG  . LYS B 2 189 ? 31.999  52.912  27.494 1   52.8   ? 170 LYS L CG  1 
ATOM   2929  C  CD  . LYS B 2 189 ? 33.213  53.456  26.771 1   54.87  ? 170 LYS L CD  1 
ATOM   2930  C  CE  . LYS B 2 189 ? 33.499  52.75   25.462 1   55.73  ? 170 LYS L CE  1 
ATOM   2931  N  NZ  . LYS B 2 189 ? 34.637  53.387  24.761 1   58.54  ? 170 LYS L NZ  1 
ATOM   2932  N  N   . GLN B 2 190 ? 29.918  55.829  28.634 1   49.85  ? 171 GLN L N   1 
ATOM   2933  C  CA  . GLN B 2 190 ? 28.512  56.182  28.295 1   54.19  ? 171 GLN L CA  1 
ATOM   2934  C  C   . GLN B 2 190 ? 27.988  55.228  27.21  1   58.25  ? 171 GLN L C   1 
ATOM   2935  O  O   . GLN B 2 190 ? 28.803  54.5    26.596 1   59.96  ? 171 GLN L O   1 
ATOM   2936  C  CB  . GLN B 2 190 ? 28.405  57.618  27.771 1   54.91  ? 171 GLN L CB  1 
ATOM   2937  C  CG  . GLN B 2 190 ? 28.926  58.692  28.72  1   54.34  ? 171 GLN L CG  1 
ATOM   2938  C  CD  . GLN B 2 190 ? 28.727  60.109  28.225 1   55.74  ? 171 GLN L CD  1 
ATOM   2939  O  OE1 . GLN B 2 190 ? 28.599  61.042  29.011 1   56.59  ? 171 GLN L OE1 1 
ATOM   2940  N  NE2 . GLN B 2 190 ? 28.708  60.308  26.915 1   56.95  ? 171 GLN L NE2 1 
ATOM   2941  N  N   . SER B 2 191 ? 26.679  55.286  26.947 1   60.95  ? 172 SER L N   1 
ATOM   2942  C  CA  . SER B 2 191 ? 25.969  54.524  25.885 1   63.52  ? 172 SER L CA  1 
ATOM   2943  C  C   . SER B 2 191 ? 26.499  54.881  24.487 1   64.01  ? 172 SER L C   1 
ATOM   2944  O  O   . SER B 2 191 ? 26.352  54.03   23.595 1   68.65  ? 172 SER L O   1 
ATOM   2945  C  CB  . SER B 2 191 ? 24.48   54.747  25.967 1   66.99  ? 172 SER L CB  1 
ATOM   2946  O  OG  . SER B 2 191 ? 24.177  56.134  25.955 1   70.7   ? 172 SER L OG  1 
ATOM   2947  N  N   . ASN B 2 192 ? 27.079  56.077  24.298 1   65.14  ? 173 ASN L N   1 
ATOM   2948  C  CA  . ASN B 2 192 ? 27.552  56.595  22.98  1   64.11  ? 173 ASN L CA  1 
ATOM   2949  C  C   . ASN B 2 192 ? 29.085  56.478  22.839 1   62.68  ? 173 ASN L C   1 
ATOM   2950  O  O   . ASN B 2 192 ? 29.64   57.197  21.98  1   60.9   ? 173 ASN L O   1 
ATOM   2951  C  CB  . ASN B 2 192 ? 27.04   58.023  22.74  1   63.92  ? 173 ASN L CB  1 
ATOM   2952  C  CG  . ASN B 2 192 ? 27.667  59.08   23.627 1   63.9   ? 173 ASN L CG  1 
ATOM   2953  O  OD1 . ASN B 2 192 ? 28.309  58.769  24.628 1   62.46  ? 173 ASN L OD1 1 
ATOM   2954  N  ND2 . ASN B 2 192 ? 27.483  60.341  23.267 1   64.22  ? 173 ASN L ND2 1 
ATOM   2955  N  N   . ASN B 2 193 ? 29.741  55.625  23.643 1   61.45  ? 174 ASN L N   1 
ATOM   2956  C  CA  . ASN B 2 193 ? 31.194  55.282  23.595 1   59.33  ? 174 ASN L CA  1 
ATOM   2957  C  C   . ASN B 2 193 ? 32.083  56.374  24.206 1   56.34  ? 174 ASN L C   1 
ATOM   2958  O  O   . ASN B 2 193 ? 33.279  56.078  24.405 1   55.82  ? 174 ASN L O   1 
ATOM   2959  C  CB  . ASN B 2 193 ? 31.704  54.97   22.184 1   61.16  ? 174 ASN L CB  1 
ATOM   2960  C  CG  . ASN B 2 193 ? 31.098  53.707  21.619 1   61.22  ? 174 ASN L CG  1 
ATOM   2961  O  OD1 . ASN B 2 193 ? 31.191  52.654  22.245 1   63.45  ? 174 ASN L OD1 1 
ATOM   2962  N  ND2 . ASN B 2 193 ? 30.489  53.8    20.446 1   60.69  ? 174 ASN L ND2 1 
ATOM   2963  N  N   . LYS B 2 194 ? 31.556  57.571  24.489 1   53.93  ? 175 LYS L N   1 
ATOM   2964  C  CA  . LYS B 2 194 ? 32.297  58.646  25.203 1   53.11  ? 175 LYS L CA  1 
ATOM   2965  C  C   . LYS B 2 194 ? 32.19   58.367  26.707 1   50.17  ? 175 LYS L C   1 
ATOM   2966  O  O   . LYS B 2 194 ? 31.524  57.377  27.076 1   51.15  ? 175 LYS L O   1 
ATOM   2967  C  CB  . LYS B 2 194 ? 31.771  60.025  24.794 1   56.46  ? 175 LYS L CB  1 
ATOM   2968  C  CG  . LYS B 2 194 ? 31.705  60.27   23.29  1   59.46  ? 175 LYS L CG  1 
ATOM   2969  C  CD  . LYS B 2 194 ? 31.581  61.735  22.907 1   63.84  ? 175 LYS L CD  1 
ATOM   2970  C  CE  . LYS B 2 194 ? 30.712  61.979  21.69  1   67.19  ? 175 LYS L CE  1 
ATOM   2971  N  NZ  . LYS B 2 194 ? 31.242  61.308  20.479 1   70.48  ? 175 LYS L NZ  1 
ATOM   2972  N  N   . TYR B 2 195 ? 32.843  59.182  27.539 1   46.85  ? 176 TYR L N   1 
ATOM   2973  C  CA  . TYR B 2 195 ? 32.99   58.941  29     1   44.42  ? 176 TYR L CA  1 
ATOM   2974  C  C   . TYR B 2 195 ? 32.303  60.048  29.802 1   42.68  ? 176 TYR L C   1 
ATOM   2975  O  O   . TYR B 2 195 ? 32.247  61.204  29.341 1   42.96  ? 176 TYR L O   1 
ATOM   2976  C  CB  . TYR B 2 195 ? 34.464  58.829  29.385 1   44.67  ? 176 TYR L CB  1 
ATOM   2977  C  CG  . TYR B 2 195 ? 35.142  57.586  28.869 1   46.27  ? 176 TYR L CG  1 
ATOM   2978  C  CD1 . TYR B 2 195 ? 35.708  57.556  27.603 1   46.69  ? 176 TYR L CD1 1 
ATOM   2979  C  CD2 . TYR B 2 195 ? 35.22   56.439  29.643 1   46.53  ? 176 TYR L CD2 1 
ATOM   2980  C  CE1 . TYR B 2 195 ? 36.333  56.417  27.122 1   49.01  ? 176 TYR L CE1 1 
ATOM   2981  C  CE2 . TYR B 2 195 ? 35.846  55.294  29.18  1   47.26  ? 176 TYR L CE2 1 
ATOM   2982  C  CZ  . TYR B 2 195 ? 36.403  55.283  27.913 1   48.92  ? 176 TYR L CZ  1 
ATOM   2983  O  OH  . TYR B 2 195 ? 37.024  54.161  27.449 1   50.32  ? 176 TYR L OH  1 
ATOM   2984  N  N   . ALA B 2 196 ? 31.787  59.675  30.976 1   40.65  ? 177 ALA L N   1 
ATOM   2985  C  CA  . ALA B 2 196 ? 31.203  60.58   31.989 1   38.53  ? 177 ALA L CA  1 
ATOM   2986  C  C   . ALA B 2 196 ? 32.006  60.463  33.285 1   37.38  ? 177 ALA L C   1 
ATOM   2987  O  O   . ALA B 2 196 ? 32.515  59.365  33.575 1   38.06  ? 177 ALA L O   1 
ATOM   2988  C  CB  . ALA B 2 196 ? 29.751  60.245  32.223 1   37.23  ? 177 ALA L CB  1 
ATOM   2989  N  N   . ALA B 2 197 ? 32.113  61.568  34.023 1   36.21  ? 178 ALA L N   1 
ATOM   2990  C  CA  . ALA B 2 197 ? 32.604  61.609  35.417 1   35.4   ? 178 ALA L CA  1 
ATOM   2991  C  C   . ALA B 2 197 ? 31.993  62.809  36.138 1   35.83  ? 178 ALA L C   1 
ATOM   2992  O  O   . ALA B 2 197 ? 31.547  63.76   35.469 1   35.78  ? 178 ALA L O   1 
ATOM   2993  C  CB  . ALA B 2 197 ? 34.109  61.66   35.445 1   36.3   ? 178 ALA L CB  1 
ATOM   2994  N  N   . SER B 2 198 ? 31.967  62.742  37.465 1   36.56  ? 179 SER L N   1 
ATOM   2995  C  CA  . SER B 2 198 ? 31.434  63.799  38.357 1   37.95  ? 179 SER L CA  1 
ATOM   2996  C  C   . SER B 2 198 ? 32.489  64.133  39.412 1   38.91  ? 179 SER L C   1 
ATOM   2997  O  O   . SER B 2 198 ? 33.323  63.255  39.72  1   39.74  ? 179 SER L O   1 
ATOM   2998  C  CB  . SER B 2 198 ? 30.124  63.379  38.973 1   39.24  ? 179 SER L CB  1 
ATOM   2999  O  OG  . SER B 2 198 ? 30.147  62.012  39.354 1   40.22  ? 179 SER L OG  1 
ATOM   3000  N  N   . SER B 2 199 ? 32.478  65.371  39.902 1   37.54  ? 180 SER L N   1 
ATOM   3001  C  CA  . SER B 2 199 ? 33.326  65.834  41.027 1   37.71  ? 180 SER L CA  1 
ATOM   3002  C  C   . SER B 2 199 ? 32.474  66.694  41.963 1   38.04  ? 180 SER L C   1 
ATOM   3003  O  O   . SER B 2 199 ? 31.601  67.434  41.468 1   39.31  ? 180 SER L O   1 
ATOM   3004  C  CB  . SER B 2 199 ? 34.546  66.563  40.532 1   38.21  ? 180 SER L CB  1 
ATOM   3005  O  OG  . SER B 2 199 ? 35.509  66.69   41.567 1   37.4   ? 180 SER L OG  1 
ATOM   3006  N  N   . TYR B 2 200 ? 32.715  66.574  43.267 1   38.15  ? 181 TYR L N   1 
ATOM   3007  C  CA  . TYR B 2 200 ? 31.903  67.183  44.348 1   38.17  ? 181 TYR L CA  1 
ATOM   3008  C  C   . TYR B 2 200 ? 32.839  67.92   45.308 1   37.33  ? 181 TYR L C   1 
ATOM   3009  O  O   . TYR B 2 200 ? 33.829  67.306  45.729 1   37.07  ? 181 TYR L O   1 
ATOM   3010  C  CB  . TYR B 2 200 ? 31.112  66.1    45.085 1   38.77  ? 181 TYR L CB  1 
ATOM   3011  C  CG  . TYR B 2 200 ? 30.114  65.345  44.245 1   39.46  ? 181 TYR L CG  1 
ATOM   3012  C  CD1 . TYR B 2 200 ? 30.497  64.257  43.473 1   40.34  ? 181 TYR L CD1 1 
ATOM   3013  C  CD2 . TYR B 2 200 ? 28.772  65.694  44.249 1   39.81  ? 181 TYR L CD2 1 
ATOM   3014  C  CE1 . TYR B 2 200 ? 29.578  63.551  42.71  1   40.4   ? 181 TYR L CE1 1 
ATOM   3015  C  CE2 . TYR B 2 200 ? 27.839  64.995  43.5   1   39.89  ? 181 TYR L CE2 1 
ATOM   3016  C  CZ  . TYR B 2 200 ? 28.243  63.921  42.725 1   40.54  ? 181 TYR L CZ  1 
ATOM   3017  O  OH  . TYR B 2 200 ? 27.323  63.243  41.98  1   39.76  ? 181 TYR L OH  1 
ATOM   3018  N  N   . LEU B 2 201 ? 32.549  69.187  45.619 1   36.75  ? 182 LEU L N   1 
ATOM   3019  C  CA  . LEU B 2 201 ? 33.275  69.963  46.658 1   36.81  ? 182 LEU L CA  1 
ATOM   3020  C  C   . LEU B 2 201 ? 32.343  70.123  47.86  1   37.29  ? 182 LEU L C   1 
ATOM   3021  O  O   . LEU B 2 201 ? 31.388  70.897  47.752 1   37.68  ? 182 LEU L O   1 
ATOM   3022  C  CB  . LEU B 2 201 ? 33.732  71.315  46.093 1   36.63  ? 182 LEU L CB  1 
ATOM   3023  C  CG  . LEU B 2 201 ? 34.681  72.117  46.986 1   36.06  ? 182 LEU L CG  1 
ATOM   3024  C  CD1 . LEU B 2 201 ? 36.054  71.468  47.054 1   37.52  ? 182 LEU L CD1 1 
ATOM   3025  C  CD2 . LEU B 2 201 ? 34.809  73.55   46.501 1   36.09  ? 182 LEU L CD2 1 
ATOM   3026  N  N   . SER B 2 202 ? 32.59   69.37   48.936 1   38.81  ? 183 SER L N   1 
ATOM   3027  C  CA  . SER B 2 202 ? 31.94   69.548  50.26  1   38.52  ? 183 SER L CA  1 
ATOM   3028  C  C   . SER B 2 202 ? 32.472  70.834  50.895 1   38.03  ? 183 SER L C   1 
ATOM   3029  O  O   . SER B 2 202 ? 33.701  70.948  51.073 1   36.04  ? 183 SER L O   1 
ATOM   3030  C  CB  . SER B 2 202 ? 32.165  68.371  51.165 1   39.82  ? 183 SER L CB  1 
ATOM   3031  O  OG  . SER B 2 202 ? 31.599  67.194  50.612 1   42.68  ? 183 SER L OG  1 
ATOM   3032  N  N   . LEU B 2 203 ? 31.573  71.777  51.163 1   38.05  ? 184 LEU L N   1 
ATOM   3033  C  CA  . LEU B 2 203 ? 31.827  73.002  51.956 1   39.68  ? 184 LEU L CA  1 
ATOM   3034  C  C   . LEU B 2 203 ? 30.834  73.025  53.119 1   39.2   ? 184 LEU L C   1 
ATOM   3035  O  O   . LEU B 2 203 ? 29.91   72.197  53.132 1   42.48  ? 184 LEU L O   1 
ATOM   3036  C  CB  . LEU B 2 203 ? 31.644  74.227  51.055 1   41.83  ? 184 LEU L CB  1 
ATOM   3037  C  CG  . LEU B 2 203 ? 32.532  74.29   49.811 1   43.22  ? 184 LEU L CG  1 
ATOM   3038  C  CD1 . LEU B 2 203 ? 32.123  75.451  48.92  1   44.15  ? 184 LEU L CD1 1 
ATOM   3039  C  CD2 . LEU B 2 203 ? 33.998  74.419  50.19  1   43.37  ? 184 LEU L CD2 1 
ATOM   3040  N  N   . THR B 2 204 ? 31.047  73.916  54.079 1   38.97  ? 185 THR L N   1 
ATOM   3041  C  CA  . THR B 2 204 ? 30.013  74.34   55.054 1   38.56  ? 185 THR L CA  1 
ATOM   3042  C  C   . THR B 2 204 ? 29.282  75.524  54.429 1   37.7   ? 185 THR L C   1 
ATOM   3043  O  O   . THR B 2 204 ? 29.849  76.208  53.575 1   37.31  ? 185 THR L O   1 
ATOM   3044  C  CB  . THR B 2 204 ? 30.643  74.664  56.413 1   38.83  ? 185 THR L CB  1 
ATOM   3045  O  OG1 . THR B 2 204 ? 31.525  75.776  56.239 1   40.26  ? 185 THR L OG1 1 
ATOM   3046  C  CG2 . THR B 2 204 ? 31.391  73.486  56.998 1   37.56  ? 185 THR L CG2 1 
ATOM   3047  N  N   . PRO B 2 205 ? 28.008  75.795  54.801 1   36.4   ? 186 PRO L N   1 
ATOM   3048  C  CA  . PRO B 2 205 ? 27.328  77.014  54.363 1   36.42  ? 186 PRO L CA  1 
ATOM   3049  C  C   . PRO B 2 205 ? 28.167  78.285  54.572 1   36.91  ? 186 PRO L C   1 
ATOM   3050  O  O   . PRO B 2 205 ? 28.181  79.137  53.696 1   36.55  ? 186 PRO L O   1 
ATOM   3051  C  CB  . PRO B 2 205 ? 26.086  77.049  55.259 1   36.33  ? 186 PRO L CB  1 
ATOM   3052  C  CG  . PRO B 2 205 ? 25.79   75.593  55.519 1   36.83  ? 186 PRO L CG  1 
ATOM   3053  C  CD  . PRO B 2 205 ? 27.148  74.938  55.632 1   36.52  ? 186 PRO L CD  1 
ATOM   3054  N  N   . GLU B 2 206 ? 28.853  78.364  55.716 1   37.34  ? 187 GLU L N   1 
ATOM   3055  C  CA  . GLU B 2 206 ? 29.64   79.551  56.139 1   38.7   ? 187 GLU L CA  1 
ATOM   3056  C  C   . GLU B 2 206 ? 30.827  79.749  55.187 1   39.08  ? 187 GLU L C   1 
ATOM   3057  O  O   . GLU B 2 206 ? 31.087  80.91   54.812 1   38.94  ? 187 GLU L O   1 
ATOM   3058  C  CB  . GLU B 2 206 ? 30.046  79.407  57.607 1   39.34  ? 187 GLU L CB  1 
ATOM   3059  C  CG  . GLU B 2 206 ? 28.866  79.495  58.569 1   39.71  ? 187 GLU L CG  1 
ATOM   3060  C  CD  . GLU B 2 206 ? 28.259  78.183  59.039 1   42.5   ? 187 GLU L CD  1 
ATOM   3061  O  OE1 . GLU B 2 206 ? 28.491  77.136  58.398 1   43.45  ? 187 GLU L OE1 1 
ATOM   3062  O  OE2 . GLU B 2 206 ? 27.547  78.212  60.058 1   46.83  ? 187 GLU L OE2 1 
ATOM   3063  N  N   . GLN B 2 207 ? 31.499  78.663  54.791 1   39.38  ? 188 GLN L N   1 
ATOM   3064  C  CA  . GLN B 2 207 ? 32.597  78.683  53.789 1   40.14  ? 188 GLN L CA  1 
ATOM   3065  C  C   . GLN B 2 207 ? 32.064  79.171  52.442 1   41.59  ? 188 GLN L C   1 
ATOM   3066  O  O   . GLN B 2 207 ? 32.714  80.036  51.837 1   41.37  ? 188 GLN L O   1 
ATOM   3067  C  CB  . GLN B 2 207 ? 33.186  77.292  53.57  1   41.52  ? 188 GLN L CB  1 
ATOM   3068  C  CG  . GLN B 2 207 ? 34.219  76.881  54.6   1   40.78  ? 188 GLN L CG  1 
ATOM   3069  C  CD  . GLN B 2 207 ? 34.744  75.51   54.257 1   40.38  ? 188 GLN L CD  1 
ATOM   3070  O  OE1 . GLN B 2 207 ? 33.98   74.553  54.15  1   41.37  ? 188 GLN L OE1 1 
ATOM   3071  N  NE2 . GLN B 2 207 ? 36.049  75.405  54.056 1   39.28  ? 188 GLN L NE2 1 
ATOM   3072  N  N   . TRP B 2 208 ? 30.951  78.588  51.981 1   43.41  ? 189 TRP L N   1 
ATOM   3073  C  CA  . TRP B 2 208 ? 30.278  78.937  50.7   1   44.28  ? 189 TRP L CA  1 
ATOM   3074  C  C   . TRP B 2 208 ? 30.078  80.457  50.635 1   46.29  ? 189 TRP L C   1 
ATOM   3075  O  O   . TRP B 2 208 ? 30.59   81.071  49.674 1   45.68  ? 189 TRP L O   1 
ATOM   3076  C  CB  . TRP B 2 208 ? 28.961  78.155  50.547 1   44.93  ? 189 TRP L CB  1 
ATOM   3077  C  CG  . TRP B 2 208 ? 28.078  78.622  49.429 1   44.76  ? 189 TRP L CG  1 
ATOM   3078  C  CD1 . TRP B 2 208 ? 26.81   79.116  49.535 1   45.43  ? 189 TRP L CD1 1 
ATOM   3079  C  CD2 . TRP B 2 208 ? 28.404  78.657  48.028 1   43.96  ? 189 TRP L CD2 1 
ATOM   3080  N  NE1 . TRP B 2 208 ? 26.331  79.468  48.302 1   44.81  ? 189 TRP L NE1 1 
ATOM   3081  C  CE2 . TRP B 2 208 ? 27.284  79.197  47.358 1   43.78  ? 189 TRP L CE2 1 
ATOM   3082  C  CE3 . TRP B 2 208 ? 29.531  78.295  47.279 1   43.35  ? 189 TRP L CE3 1 
ATOM   3083  C  CZ2 . TRP B 2 208 ? 27.257  79.367  45.974 1   43.94  ? 189 TRP L CZ2 1 
ATOM   3084  C  CZ3 . TRP B 2 208 ? 29.507  78.472  45.912 1   43.64  ? 189 TRP L CZ3 1 
ATOM   3085  C  CH2 . TRP B 2 208 ? 28.382  78.996  45.271 1   44.26  ? 189 TRP L CH2 1 
ATOM   3086  N  N   . LYS B 2 209 ? 29.431  81.037  51.655 1   49.06  ? 190 LYS L N   1 
ATOM   3087  C  CA  . LYS B 2 209 ? 29.021  82.472  51.709 1   52.13  ? 190 LYS L CA  1 
ATOM   3088  C  C   . LYS B 2 209 ? 30.247  83.396  51.746 1   51.17  ? 190 LYS L C   1 
ATOM   3089  O  O   . LYS B 2 209 ? 30.153  84.503  51.182 1   56.27  ? 190 LYS L O   1 
ATOM   3090  C  CB  . LYS B 2 209 ? 28.121  82.738  52.921 1   54.62  ? 190 LYS L CB  1 
ATOM   3091  C  CG  . LYS B 2 209 ? 26.754  82.064  52.864 1   60.99  ? 190 LYS L CG  1 
ATOM   3092  C  CD  . LYS B 2 209 ? 26.165  81.71   54.223 1   66.22  ? 190 LYS L CD  1 
ATOM   3093  C  CE  . LYS B 2 209 ? 25.189  80.549  54.186 1   70.45  ? 190 LYS L CE  1 
ATOM   3094  N  NZ  . LYS B 2 209 ? 23.885  80.928  53.59  1   73.58  ? 190 LYS L NZ  1 
ATOM   3095  N  N   . SER B 2 210 ? 31.352  82.969  52.361 1   49.77  ? 191 SER L N   1 
ATOM   3096  C  CA  . SER B 2 210 ? 32.501  83.843  52.722 1   50.15  ? 191 SER L CA  1 
ATOM   3097  C  C   . SER B 2 210 ? 33.648  83.765  51.693 1   49.65  ? 191 SER L C   1 
ATOM   3098  O  O   . SER B 2 210 ? 34.783  84.112  52.066 1   50.34  ? 191 SER L O   1 
ATOM   3099  C  CB  . SER B 2 210 ? 32.952  83.539  54.136 1   50.84  ? 191 SER L CB  1 
ATOM   3100  O  OG  . SER B 2 210 ? 33.156  82.149  54.332 1   53.4   ? 191 SER L OG  1 
ATOM   3101  N  N   . HIS B 2 211 ? 33.374  83.384  50.435 1   50.21  ? 192 HIS L N   1 
ATOM   3102  C  CA  . HIS B 2 211 ? 34.279  83.59   49.265 1   50.17  ? 192 HIS L CA  1 
ATOM   3103  C  C   . HIS B 2 211 ? 33.495  84.178  48.089 1   50.89  ? 192 HIS L C   1 
ATOM   3104  O  O   . HIS B 2 211 ? 32.298  83.867  47.958 1   49.93  ? 192 HIS L O   1 
ATOM   3105  C  CB  . HIS B 2 211 ? 34.987  82.297  48.834 1   51.24  ? 192 HIS L CB  1 
ATOM   3106  C  CG  . HIS B 2 211 ? 35.714  81.617  49.938 1   50.35  ? 192 HIS L CG  1 
ATOM   3107  N  ND1 . HIS B 2 211 ? 35.049  80.798  50.806 1   51.64  ? 192 HIS L ND1 1 
ATOM   3108  C  CD2 . HIS B 2 211 ? 37.005  81.645  50.341 1   48.43  ? 192 HIS L CD2 1 
ATOM   3109  C  CE1 . HIS B 2 211 ? 35.887  80.323  51.694 1   51.14  ? 192 HIS L CE1 1 
ATOM   3110  N  NE2 . HIS B 2 211 ? 37.106  80.832  51.443 1   47.11  ? 192 HIS L NE2 1 
ATOM   3111  N  N   . ARG B 2 212 ? 34.171  84.972  47.255 1   54.56  ? 193 ARG L N   1 
ATOM   3112  C  CA  . ARG B 2 212 ? 33.575  85.675  46.088 1   59.22  ? 193 ARG L CA  1 
ATOM   3113  C  C   . ARG B 2 212 ? 33.036  84.642  45.09  1   56.97  ? 193 ARG L C   1 
ATOM   3114  O  O   . ARG B 2 212 ? 31.949  84.887  44.534 1   58.63  ? 193 ARG L O   1 
ATOM   3115  C  CB  . ARG B 2 212 ? 34.606  86.588  45.416 1   65.91  ? 193 ARG L CB  1 
ATOM   3116  C  CG  . ARG B 2 212 ? 35.093  87.741  46.286 1   72.9   ? 193 ARG L CG  1 
ATOM   3117  C  CD  . ARG B 2 212 ? 36.143  88.603  45.599 1   77.53  ? 193 ARG L CD  1 
ATOM   3118  N  NE  . ARG B 2 212 ? 37.167  89.083  46.527 1   81.12  ? 193 ARG L NE  1 
ATOM   3119  C  CZ  . ARG B 2 212 ? 38.315  88.464  46.834 1   82.91  ? 193 ARG L CZ  1 
ATOM   3120  N  NH1 . ARG B 2 212 ? 38.644  87.3    46.289 1   80.7   ? 193 ARG L NH1 1 
ATOM   3121  N  NH2 . ARG B 2 212 ? 39.145  89.025  47.7   1   84.83  ? 193 ARG L NH2 1 
ATOM   3122  N  N   . SER B 2 213 ? 33.763  83.538  44.874 1   52.59  ? 194 SER L N   1 
ATOM   3123  C  CA  . SER B 2 213 ? 33.424  82.492  43.871 1   49.37  ? 194 SER L CA  1 
ATOM   3124  C  C   . SER B 2 213 ? 34.09   81.151  44.192 1   46.85  ? 194 SER L C   1 
ATOM   3125  O  O   . SER B 2 213 ? 35.001  81.109  45.039 1   47.35  ? 194 SER L O   1 
ATOM   3126  C  CB  . SER B 2 213 ? 33.809  82.942  42.487 1   48.87  ? 194 SER L CB  1 
ATOM   3127  O  OG  . SER B 2 213 ? 35.217  83.066  42.371 1   48.42  ? 194 SER L OG  1 
ATOM   3128  N  N   . TYR B 2 214 ? 33.635  80.101  43.508 1   42.61  ? 195 TYR L N   1 
ATOM   3129  C  CA  . TYR B 2 214 ? 34.273  78.763  43.436 1   42.15  ? 195 TYR L CA  1 
ATOM   3130  C  C   . TYR B 2 214 ? 34.287  78.3    41.976 1   41.84  ? 195 TYR L C   1 
ATOM   3131  O  O   . TYR B 2 214 ? 33.286  78.53   41.275 1   43.43  ? 195 TYR L O   1 
ATOM   3132  C  CB  . TYR B 2 214 ? 33.516  77.759  44.304 1   42.42  ? 195 TYR L CB  1 
ATOM   3133  C  CG  . TYR B 2 214 ? 33.727  77.91   45.787 1   41.86  ? 195 TYR L CG  1 
ATOM   3134  C  CD1 . TYR B 2 214 ? 32.954  78.783  46.539 1   40.67  ? 195 TYR L CD1 1 
ATOM   3135  C  CD2 . TYR B 2 214 ? 34.695  77.166  46.44  1   42.08  ? 195 TYR L CD2 1 
ATOM   3136  C  CE1 . TYR B 2 214 ? 33.14   78.916  47.905 1   41.29  ? 195 TYR L CE1 1 
ATOM   3137  C  CE2 . TYR B 2 214 ? 34.892  77.286  47.806 1   43.22  ? 195 TYR L CE2 1 
ATOM   3138  C  CZ  . TYR B 2 214 ? 34.118  78.169  48.539 1   42.65  ? 195 TYR L CZ  1 
ATOM   3139  O  OH  . TYR B 2 214 ? 34.321  78.28   49.884 1   43.54  ? 195 TYR L OH  1 
ATOM   3140  N  N   . SER B 2 215 ? 35.373  77.661  41.54  1   40.32  ? 196 SER L N   1 
ATOM   3141  C  CA  . SER B 2 215 ? 35.559  77.188  40.145 1   40.65  ? 196 SER L CA  1 
ATOM   3142  C  C   . SER B 2 215 ? 35.866  75.688  40.118 1   39.5   ? 196 SER L C   1 
ATOM   3143  O  O   . SER B 2 215 ? 36.498  75.184  41.064 1   37.7   ? 196 SER L O   1 
ATOM   3144  C  CB  . SER B 2 215 ? 36.623  77.981  39.446 1   42.07  ? 196 SER L CB  1 
ATOM   3145  O  OG  . SER B 2 215 ? 36.234  79.34   39.341 1   46.15  ? 196 SER L OG  1 
ATOM   3146  N  N   . CYS B 2 216 ? 35.391  75.014  39.07  1   39.46  ? 197 CYS L N   1 
ATOM   3147  C  CA  . CYS B 2 216 ? 35.701  73.607  38.718 1   40.13  ? 197 CYS L CA  1 
ATOM   3148  C  C   . CYS B 2 216 ? 36.389  73.616  37.352 1   39.94  ? 197 CYS L C   1 
ATOM   3149  O  O   . CYS B 2 216 ? 35.714  73.958  36.366 1   40.34  ? 197 CYS L O   1 
ATOM   3150  C  CB  . CYS B 2 216 ? 34.438  72.752  38.676 1   41.27  ? 197 CYS L CB  1 
ATOM   3151  S  SG  . CYS B 2 216 ? 34.755  71.043  38.166 1   41.99  ? 197 CYS L SG  1 
ATOM   3152  N  N   . GLN B 2 217 ? 37.683  73.289  37.317 1   40.3   ? 198 GLN L N   1 
ATOM   3153  C  CA  . GLN B 2 217 ? 38.525  73.268  36.092 1   41.26  ? 198 GLN L CA  1 
ATOM   3154  C  C   . GLN B 2 217 ? 38.734  71.811  35.671 1   39.37  ? 198 GLN L C   1 
ATOM   3155  O  O   . GLN B 2 217 ? 39.286  71.048  36.472 1   38.8   ? 198 GLN L O   1 
ATOM   3156  C  CB  . GLN B 2 217 ? 39.858  73.964  36.364 1   43.4   ? 198 GLN L CB  1 
ATOM   3157  C  CG  . GLN B 2 217 ? 39.732  75.466  36.569 1   46.35  ? 198 GLN L CG  1 
ATOM   3158  C  CD  . GLN B 2 217 ? 40.965  76.091  37.179 1   49.82  ? 198 GLN L CD  1 
ATOM   3159  O  OE1 . GLN B 2 217 ? 41.693  75.467  37.953 1   53.52  ? 198 GLN L OE1 1 
ATOM   3160  N  NE2 . GLN B 2 217 ? 41.199  77.354  36.858 1   50.25  ? 198 GLN L NE2 1 
ATOM   3161  N  N   . VAL B 2 218 ? 38.295  71.443  34.468 1   39.59  ? 199 VAL L N   1 
ATOM   3162  C  CA  . VAL B 2 218 ? 38.421  70.062  33.913 1   41.5   ? 199 VAL L CA  1 
ATOM   3163  C  C   . VAL B 2 218 ? 39.435  70.105  32.764 1   41.94  ? 199 VAL L C   1 
ATOM   3164  O  O   . VAL B 2 218 ? 39.08   70.602  31.683 1   41.89  ? 199 VAL L O   1 
ATOM   3165  C  CB  . VAL B 2 218 ? 37.054  69.511  33.457 1   41.74  ? 199 VAL L CB  1 
ATOM   3166  C  CG1 . VAL B 2 218 ? 37.163  68.099  32.891 1   41.33  ? 199 VAL L CG1 1 
ATOM   3167  C  CG2 . VAL B 2 218 ? 36.029  69.552  34.58  1   41.95  ? 199 VAL L CG2 1 
ATOM   3168  N  N   . THR B 2 219 ? 40.65   69.606  32.998 1   43.27  ? 200 THR L N   1 
ATOM   3169  C  CA  . THR B 2 219 ? 41.703  69.46   31.961 1   45.13  ? 200 THR L CA  1 
ATOM   3170  C  C   . THR B 2 219 ? 41.495  68.129  31.236 1   46.8   ? 200 THR L C   1 
ATOM   3171  O  O   . THR B 2 219 ? 41.466  67.082  31.913 1   46.79  ? 200 THR L O   1 
ATOM   3172  C  CB  . THR B 2 219 ? 43.11   69.566  32.557 1   46.12  ? 200 THR L CB  1 
ATOM   3173  O  OG1 . THR B 2 219 ? 43.124  70.743  33.364 1   48.15  ? 200 THR L OG1 1 
ATOM   3174  C  CG2 . THR B 2 219 ? 44.195  69.638  31.502 1   44.91  ? 200 THR L CG2 1 
ATOM   3175  N  N   . HIS B 2 220 ? 41.355  68.19   29.91  1   47.27  ? 201 HIS L N   1 
ATOM   3176  C  CA  . HIS B 2 220 ? 41.2    67.025  29.004 1   46.75  ? 201 HIS L CA  1 
ATOM   3177  C  C   . HIS B 2 220 ? 42.188  67.17   27.842 1   47.89  ? 201 HIS L C   1 
ATOM   3178  O  O   . HIS B 2 220 ? 42.025  68.124  27.052 1   50.11  ? 201 HIS L O   1 
ATOM   3179  C  CB  . HIS B 2 220 ? 39.744  66.925  28.533 1   46.6   ? 201 HIS L CB  1 
ATOM   3180  C  CG  . HIS B 2 220 ? 39.513  65.783  27.609 1   45.49  ? 201 HIS L CG  1 
ATOM   3181  N  ND1 . HIS B 2 220 ? 39.497  65.954  26.246 1   45.85  ? 201 HIS L ND1 1 
ATOM   3182  C  CD2 . HIS B 2 220 ? 39.346  64.464  27.839 1   44.42  ? 201 HIS L CD2 1 
ATOM   3183  C  CE1 . HIS B 2 220 ? 39.307  64.789  25.668 1   46.68  ? 201 HIS L CE1 1 
ATOM   3184  N  NE2 . HIS B 2 220 ? 39.211  63.855  26.625 1   45.99  ? 201 HIS L NE2 1 
ATOM   3185  N  N   . GLU B 2 221 ? 43.181  66.276  27.761 1   49.54  ? 202 GLU L N   1 
ATOM   3186  C  CA  . GLU B 2 221 ? 44.229  66.249  26.703 1   49.25  ? 202 GLU L CA  1 
ATOM   3187  C  C   . GLU B 2 221 ? 44.795  67.664  26.497 1   47.8   ? 202 GLU L C   1 
ATOM   3188  O  O   . GLU B 2 221 ? 44.856  68.114  25.343 1   47.85  ? 202 GLU L O   1 
ATOM   3189  C  CB  . GLU B 2 221 ? 43.645  65.661  25.415 1   50.73  ? 202 GLU L CB  1 
ATOM   3190  C  CG  . GLU B 2 221 ? 43.133  64.233  25.559 1   52.53  ? 202 GLU L CG  1 
ATOM   3191  C  CD  . GLU B 2 221 ? 44.195  63.155  25.732 1   53.56  ? 202 GLU L CD  1 
ATOM   3192  O  OE1 . GLU B 2 221 ? 45.217  63.206  25.017 1   55.62  ? 202 GLU L OE1 1 
ATOM   3193  O  OE2 . GLU B 2 221 ? 43.994  62.257  26.579 1   54.74  ? 202 GLU L OE2 1 
ATOM   3194  N  N   . GLY B 2 222 ? 45.161  68.347  27.588 1   47.53  ? 203 GLY L N   1 
ATOM   3195  C  CA  . GLY B 2 222 ? 45.847  69.656  27.578 1   46.88  ? 203 GLY L CA  1 
ATOM   3196  C  C   . GLY B 2 222 ? 44.938  70.833  27.249 1   47.31  ? 203 GLY L C   1 
ATOM   3197  O  O   . GLY B 2 222 ? 45.485  71.889  26.881 1   50.56  ? 203 GLY L O   1 
ATOM   3198  N  N   . SER B 2 223 ? 43.614  70.674  27.365 1   46.66  ? 204 SER L N   1 
ATOM   3199  C  CA  . SER B 2 223 ? 42.593  71.751  27.241 1   46.87  ? 204 SER L CA  1 
ATOM   3200  C  C   . SER B 2 223 ? 41.718  71.76   28.495 1   46.09  ? 204 SER L C   1 
ATOM   3201  O  O   . SER B 2 223 ? 41.01   70.756  28.73  1   46.26  ? 204 SER L O   1 
ATOM   3202  C  CB  . SER B 2 223 ? 41.742  71.587  26.01  1   49.5   ? 204 SER L CB  1 
ATOM   3203  O  OG  . SER B 2 223 ? 42.404  72.092  24.863 1   55.44  ? 204 SER L OG  1 
ATOM   3204  N  N   . THR B 2 224 ? 41.761  72.857  29.255 1   45.69  ? 205 THR L N   1 
ATOM   3205  C  CA  . THR B 2 224 ? 40.98   73.058  30.501 1   44.84  ? 205 THR L CA  1 
ATOM   3206  C  C   . THR B 2 224 ? 39.66   73.751  30.153 1   45.42  ? 205 THR L C   1 
ATOM   3207  O  O   . THR B 2 224 ? 39.693  74.73   29.379 1   45.25  ? 205 THR L O   1 
ATOM   3208  C  CB  . THR B 2 224 ? 41.793  73.83   31.544 1   43.41  ? 205 THR L CB  1 
ATOM   3209  O  OG1 . THR B 2 224 ? 43.032  73.141  31.709 1   42.11  ? 205 THR L OG1 1 
ATOM   3210  C  CG2 . THR B 2 224 ? 41.09   73.931  32.879 1   44.28  ? 205 THR L CG2 1 
ATOM   3211  N  N   . VAL B 2 225 ? 38.553  73.237  30.695 1   44.39  ? 206 VAL L N   1 
ATOM   3212  C  CA  . VAL B 2 225 ? 37.199  73.862  30.652 1   45.24  ? 206 VAL L CA  1 
ATOM   3213  C  C   . VAL B 2 225 ? 36.873  74.317  32.08  1   47.3   ? 206 VAL L C   1 
ATOM   3214  O  O   . VAL B 2 225 ? 36.737  73.435  32.952 1   48.88  ? 206 VAL L O   1 
ATOM   3215  C  CB  . VAL B 2 225 ? 36.147  72.875  30.104 1   44.66  ? 206 VAL L CB  1 
ATOM   3216  C  CG1 . VAL B 2 225 ? 34.765  73.504  30.012 1   46.04  ? 206 VAL L CG1 1 
ATOM   3217  C  CG2 . VAL B 2 225 ? 36.55   72.298  28.754 1   43.28  ? 206 VAL L CG2 1 
ATOM   3218  N  N   . GLU B 2 226 ? 36.788  75.633  32.312 1   48.88  ? 207 GLU L N   1 
ATOM   3219  C  CA  . GLU B 2 226 ? 36.498  76.247  33.64  1   49.4   ? 207 GLU L CA  1 
ATOM   3220  C  C   . GLU B 2 226 ? 35.019  76.643  33.727 1   47.66  ? 207 GLU L C   1 
ATOM   3221  O  O   . GLU B 2 226 ? 34.545  77.347  32.817 1   47.22  ? 207 GLU L O   1 
ATOM   3222  C  CB  . GLU B 2 226 ? 37.365  77.488  33.874 1   53.04  ? 207 GLU L CB  1 
ATOM   3223  C  CG  . GLU B 2 226 ? 37.013  78.23   35.156 1   56.33  ? 207 GLU L CG  1 
ATOM   3224  C  CD  . GLU B 2 226 ? 38.097  79.14   35.7   1   59.09  ? 207 GLU L CD  1 
ATOM   3225  O  OE1 . GLU B 2 226 ? 38.245  80.256  35.16  1   61.48  ? 207 GLU L OE1 1 
ATOM   3226  O  OE2 . GLU B 2 226 ? 38.783  78.733  36.666 1   58.48  ? 207 GLU L OE2 1 
ATOM   3227  N  N   . LYS B 2 227 ? 34.335  76.233  34.799 1   46.19  ? 208 LYS L N   1 
ATOM   3228  C  CA  . LYS B 2 227 ? 32.989  76.739  35.187 1   47.02  ? 208 LYS L CA  1 
ATOM   3229  C  C   . LYS B 2 227 ? 33.083  77.341  36.592 1   45.19  ? 208 LYS L C   1 
ATOM   3230  O  O   . LYS B 2 227 ? 33.821  76.784  37.421 1   43.46  ? 208 LYS L O   1 
ATOM   3231  C  CB  . LYS B 2 227 ? 31.943  75.624  35.119 1   48.16  ? 208 LYS L CB  1 
ATOM   3232  C  CG  . LYS B 2 227 ? 31.654  75.105  33.719 1   50.63  ? 208 LYS L CG  1 
ATOM   3233  C  CD  . LYS B 2 227 ? 30.791  76.027  32.883 1   52.28  ? 208 LYS L CD  1 
ATOM   3234  C  CE  . LYS B 2 227 ? 30.917  75.752  31.398 1   54.28  ? 208 LYS L CE  1 
ATOM   3235  N  NZ  . LYS B 2 227 ? 29.705  76.18   30.663 1   56.79  ? 208 LYS L NZ  1 
ATOM   3236  N  N   . THR B 2 228 ? 32.366  78.442  36.832 1   44.67  ? 209 THR L N   1 
ATOM   3237  C  CA  . THR B 2 228 ? 32.46   79.268  38.065 1   44.1   ? 209 THR L CA  1 
ATOM   3238  C  C   . THR B 2 228 ? 31.053  79.532  38.608 1   42.66  ? 209 THR L C   1 
ATOM   3239  O  O   . THR B 2 228 ? 30.162  79.836  37.807 1   43.1   ? 209 THR L O   1 
ATOM   3240  C  CB  . THR B 2 228 ? 33.227  80.567  37.787 1   45.02  ? 209 THR L CB  1 
ATOM   3241  O  OG1 . THR B 2 228 ? 34.482  80.24   37.185 1   43.44  ? 209 THR L OG1 1 
ATOM   3242  C  CG2 . THR B 2 228 ? 33.48   81.384  39.036 1   46.75  ? 209 THR L CG2 1 
ATOM   3243  N  N   . VAL B 2 229 ? 30.878  79.423  39.925 1   43.29  ? 210 VAL L N   1 
ATOM   3244  C  CA  . VAL B 2 229 ? 29.609  79.746  40.645 1   44.97  ? 210 VAL L CA  1 
ATOM   3245  C  C   . VAL B 2 229 ? 29.951  80.657  41.826 1   48.03  ? 210 VAL L C   1 
ATOM   3246  O  O   . VAL B 2 229 ? 30.963  80.389  42.506 1   50.13  ? 210 VAL L O   1 
ATOM   3247  C  CB  . VAL B 2 229 ? 28.853  78.487  41.112 1   45.62  ? 210 VAL L CB  1 
ATOM   3248  C  CG1 . VAL B 2 229 ? 28.117  77.815  39.966 1   46.3   ? 210 VAL L CG1 1 
ATOM   3249  C  CG2 . VAL B 2 229 ? 29.749  77.49   41.836 1   45.59  ? 210 VAL L CG2 1 
ATOM   3250  N  N   . ALA B 2 230 ? 29.14   81.695  42.042 1   50.59  ? 211 ALA L N   1 
ATOM   3251  C  CA  . ALA B 2 230 ? 29.256  82.667  43.154 1   51.3   ? 211 ALA L CA  1 
ATOM   3252  C  C   . ALA B 2 230 ? 27.999  82.583  44.02  1   52.92  ? 211 ALA L C   1 
ATOM   3253  O  O   . ALA B 2 230 ? 26.915  82.34   43.493 1   57.67  ? 211 ALA L O   1 
ATOM   3254  C  CB  . ALA B 2 230 ? 29.458  84.053  42.594 1   50.1   ? 211 ALA L CB  1 
ATOM   3255  N  N   . PRO B 2 231 ? 28.088  82.758  45.361 1   54.62  ? 212 PRO L N   1 
ATOM   3256  C  CA  . PRO B 2 231 ? 26.891  82.864  46.202 1   57.94  ? 212 PRO L CA  1 
ATOM   3257  C  C   . PRO B 2 231 ? 26.031  84.111  45.928 1   59.83  ? 212 PRO L C   1 
ATOM   3258  O  O   . PRO B 2 231 ? 24.825  84.019  46.083 1   56     ? 212 PRO L O   1 
ATOM   3259  C  CB  . PRO B 2 231 ? 27.428  82.946  47.641 1   57.82  ? 212 PRO L CB  1 
ATOM   3260  C  CG  . PRO B 2 231 ? 28.877  82.511  47.55  1   57.08  ? 212 PRO L CG  1 
ATOM   3261  C  CD  . PRO B 2 231 ? 29.329  82.843  46.145 1   55.17  ? 212 PRO L CD  1 
ATOM   3262  N  N   . THR B 2 232 ? 26.668  85.223  45.536 1   66.48  ? 213 THR L N   1 
ATOM   3263  C  CA  . THR B 2 232 ? 26.054  86.571  45.373 1   74.98  ? 213 THR L CA  1 
ATOM   3264  C  C   . THR B 2 232 ? 25.261  86.648  44.061 1   81.84  ? 213 THR L C   1 
ATOM   3265  O  O   . THR B 2 232 ? 24.141  87.193  44.091 1   86.5   ? 213 THR L O   1 
ATOM   3266  C  CB  . THR B 2 232 ? 27.115  87.68   45.427 1   75.53  ? 213 THR L CB  1 
ATOM   3267  O  OG1 . THR B 2 232 ? 28.072  87.455  44.39  1   75.91  ? 213 THR L OG1 1 
ATOM   3268  C  CG2 . THR B 2 232 ? 27.827  87.752  46.761 1   74.93  ? 213 THR L CG2 1 
ATOM   3269  N  N   . GLU B 2 233 ? 25.828  86.141  42.96  1   89.46  ? 214 GLU L N   1 
ATOM   3270  C  CA  . GLU B 2 233 ? 25.255  86.243  41.587 1   92.63  ? 214 GLU L CA  1 
ATOM   3271  C  C   . GLU B 2 233 ? 24.22   85.133  41.363 1   91.21  ? 214 GLU L C   1 
ATOM   3272  O  O   . GLU B 2 233 ? 24.204  84.161  42.148 1   84.44  ? 214 GLU L O   1 
ATOM   3273  C  CB  . GLU B 2 233 ? 26.362  86.177  40.531 1   97.91  ? 214 GLU L CB  1 
ATOM   3274  C  CG  . GLU B 2 233 ? 27.287  87.385  40.545 1   100.99 ? 214 GLU L CG  1 
ATOM   3275  C  CD  . GLU B 2 233 ? 28.545  87.248  39.702 1   102.94 ? 214 GLU L CD  1 
ATOM   3276  O  OE1 . GLU B 2 233 ? 28.455  86.676  38.596 1   101    ? 214 GLU L OE1 1 
ATOM   3277  O  OE2 . GLU B 2 233 ? 29.613  87.713  40.154 1   104.11 ? 214 GLU L OE2 1 
ATOM   3278  N  N   . CYS B 2 234 ? 23.394  85.299  40.323 1   93.33  ? 215 CYS L N   1 
ATOM   3279  C  CA  . CYS B 2 234 ? 22.298  84.385  39.897 1   93.44  ? 215 CYS L CA  1 
ATOM   3280  C  C   . CYS B 2 234 ? 22.499  84.01   38.423 1   93.39  ? 215 CYS L C   1 
ATOM   3281  O  O   . CYS B 2 234 ? 22.655  82.842  38.063 1   92.75  ? 215 CYS L O   1 
ATOM   3282  C  CB  . CYS B 2 234 ? 20.937  85.046  40.094 1   94     ? 215 CYS L CB  1 
ATOM   3283  S  SG  . CYS B 2 234 ? 19.529  83.94   39.812 1   95.22  ? 215 CYS L SG  1 
ATOM   3284  N  N   . CYS C 3 1   ? -29.437 -1.251  31.265 1   144.76 ? 242 CYS P N   1 
ATOM   3285  C  CA  . CYS C 3 1   ? -28.08  -0.992  31.852 1   146.71 ? 242 CYS P CA  1 
ATOM   3286  C  C   . CYS C 3 1   ? -28.183 -0.791  33.371 1   152.54 ? 242 CYS P C   1 
ATOM   3287  O  O   . CYS C 3 1   ? -29.183 -0.197  33.824 1   155.88 ? 242 CYS P O   1 
ATOM   3288  C  CB  . CYS C 3 1   ? -27.42  0.223   31.207 1   145.34 ? 242 CYS P CB  1 
ATOM   3289  S  SG  . CYS C 3 1   ? -28.436 1.723   31.262 1   138.19 ? 242 CYS P SG  1 
ATOM   3290  N  N   . HIS C 3 2   ? -27.179 -1.267  34.118 1   155.57 ? 243 HIS P N   1 
ATOM   3291  C  CA  . HIS C 3 2   ? -27.087 -1.191  35.603 1   156.54 ? 243 HIS P CA  1 
ATOM   3292  C  C   . HIS C 3 2   ? -26.617 0.207   36.013 1   158.27 ? 243 HIS P C   1 
ATOM   3293  O  O   . HIS C 3 2   ? -25.633 0.697   35.46  1   159.14 ? 243 HIS P O   1 
ATOM   3294  C  CB  . HIS C 3 2   ? -26.147 -2.292  36.123 1   153.43 ? 243 HIS P CB  1 
ATOM   3295  C  CG  . HIS C 3 2   ? -26.212 -2.525  37.596 1   149.96 ? 243 HIS P CG  1 
ATOM   3296  N  ND1 . HIS C 3 2   ? -25.42  -1.831  38.491 1   148    ? 243 HIS P ND1 1 
ATOM   3297  C  CD2 . HIS C 3 2   ? -26.952 -3.383  38.332 1   147.39 ? 243 HIS P CD2 1 
ATOM   3298  C  CE1 . HIS C 3 2   ? -25.679 -2.242  39.716 1   146.16 ? 243 HIS P CE1 1 
ATOM   3299  N  NE2 . HIS C 3 2   ? -26.615 -3.195  39.646 1   146.54 ? 243 HIS P NE2 1 
ATOM   3300  N  N   . PRO C 3 3   ? -27.298 0.912   36.954 1   158.56 ? 244 PRO P N   1 
ATOM   3301  C  CA  . PRO C 3 3   ? -26.751 2.139   37.544 1   156.97 ? 244 PRO P CA  1 
ATOM   3302  C  C   . PRO C 3 3   ? -25.454 1.884   38.334 1   156.31 ? 244 PRO P C   1 
ATOM   3303  O  O   . PRO C 3 3   ? -25.502 1.13    39.294 1   156.77 ? 244 PRO P O   1 
ATOM   3304  C  CB  . PRO C 3 3   ? -27.866 2.655   38.474 1   156.32 ? 244 PRO P CB  1 
ATOM   3305  C  CG  . PRO C 3 3   ? -29.122 1.968   37.982 1   156.87 ? 244 PRO P CG  1 
ATOM   3306  C  CD  . PRO C 3 3   ? -28.657 0.63    37.446 1   158.49 ? 244 PRO P CD  1 
ATOM   3307  N  N   . ARG C 3 4   ? -24.34  2.49    37.896 1   153.22 ? 245 ARG P N   1 
ATOM   3308  C  CA  . ARG C 3 4   ? -23.003 2.423   38.558 1   146.15 ? 245 ARG P CA  1 
ATOM   3309  C  C   . ARG C 3 4   ? -22.392 3.83    38.639 1   140.5  ? 245 ARG P C   1 
ATOM   3310  O  O   . ARG C 3 4   ? -22.511 4.588   37.653 1   140.89 ? 245 ARG P O   1 
ATOM   3311  C  CB  . ARG C 3 4   ? -22.054 1.481   37.806 1   142.28 ? 245 ARG P CB  1 
ATOM   3312  C  CG  . ARG C 3 4   ? -22.36  -0.001  37.981 1   139.28 ? 245 ARG P CG  1 
ATOM   3313  C  CD  . ARG C 3 4   ? -21.137 -0.883  37.793 1   134.61 ? 245 ARG P CD  1 
ATOM   3314  N  NE  . ARG C 3 4   ? -20.316 -0.48   36.653 1   132.33 ? 245 ARG P NE  1 
ATOM   3315  C  CZ  . ARG C 3 4   ? -20.583 -0.727  35.367 1   128.45 ? 245 ARG P CZ  1 
ATOM   3316  N  NH1 . ARG C 3 4   ? -21.671 -1.392  35.005 1   127.21 ? 245 ARG P NH1 1 
ATOM   3317  N  NH2 . ARG C 3 4   ? -19.746 -0.299  34.434 1   124.96 ? 245 ARG P NH2 1 
ATOM   3318  N  N   . LEU C 3 5   ? -21.76  4.145   39.777 1   130.84 ? 246 LEU P N   1 
ATOM   3319  C  CA  . LEU C 3 5   ? -21.051 5.423   40.062 1   124    ? 246 LEU P CA  1 
ATOM   3320  C  C   . LEU C 3 5   ? -19.582 5.105   40.374 1   123.42 ? 246 LEU P C   1 
ATOM   3321  O  O   . LEU C 3 5   ? -19.328 4.044   40.984 1   121.91 ? 246 LEU P O   1 
ATOM   3322  C  CB  . LEU C 3 5   ? -21.739 6.109   41.248 1   119.75 ? 246 LEU P CB  1 
ATOM   3323  C  CG  . LEU C 3 5   ? -21.29  7.537   41.562 1   117.22 ? 246 LEU P CG  1 
ATOM   3324  C  CD1 . LEU C 3 5   ? -21.95  8.538   40.628 1   114.47 ? 246 LEU P CD1 1 
ATOM   3325  C  CD2 . LEU C 3 5   ? -21.596 7.895   43.009 1   116.96 ? 246 LEU P CD2 1 
ATOM   3326  N  N   . SER C 3 6   ? -18.66  5.984   39.963 1   121.08 ? 247 SER P N   1 
ATOM   3327  C  CA  . SER C 3 6   ? -17.2   5.889   40.242 1   118.29 ? 247 SER P CA  1 
ATOM   3328  C  C   . SER C 3 6   ? -16.573 7.289   40.299 1   119.2  ? 247 SER P C   1 
ATOM   3329  O  O   . SER C 3 6   ? -17.048 8.182   39.56  1   116.91 ? 247 SER P O   1 
ATOM   3330  C  CB  . SER C 3 6   ? -16.5   5.017   39.224 1   113.68 ? 247 SER P CB  1 
ATOM   3331  O  OG  . SER C 3 6   ? -16.493 5.628   37.942 1   110.34 ? 247 SER P OG  1 
ATOM   3332  N  N   . LEU C 3 7   ? -15.546 7.458   41.143 1   117.11 ? 248 LEU P N   1 
ATOM   3333  C  CA  . LEU C 3 7   ? -14.73  8.699   41.259 1   113.38 ? 248 LEU P CA  1 
ATOM   3334  C  C   . LEU C 3 7   ? -13.447 8.547   40.433 1   108.38 ? 248 LEU P C   1 
ATOM   3335  O  O   . LEU C 3 7   ? -13.008 7.396   40.215 1   105.29 ? 248 LEU P O   1 
ATOM   3336  C  CB  . LEU C 3 7   ? -14.404 8.981   42.732 1   114.94 ? 248 LEU P CB  1 
ATOM   3337  C  CG  . LEU C 3 7   ? -15.462 9.756   43.517 1   118.48 ? 248 LEU P CG  1 
ATOM   3338  C  CD1 . LEU C 3 7   ? -15.143 9.746   45.005 1   119.79 ? 248 LEU P CD1 1 
ATOM   3339  C  CD2 . LEU C 3 7   ? -15.587 11.191  43.02  1   116.45 ? 248 LEU P CD2 1 
ATOM   3340  N  N   . HIS C 3 8   ? -12.885 9.677   39.99  1   104.38 ? 249 HIS P N   1 
ATOM   3341  C  CA  . HIS C 3 8   ? -11.577 9.777   39.285 1   103.07 ? 249 HIS P CA  1 
ATOM   3342  C  C   . HIS C 3 8   ? -10.638 10.692  40.08  1   97.17  ? 249 HIS P C   1 
ATOM   3343  O  O   . HIS C 3 8   ? -11.123 11.7    40.643 1   92.71  ? 249 HIS P O   1 
ATOM   3344  C  CB  . HIS C 3 8   ? -11.764 10.265  37.841 1   105.62 ? 249 HIS P CB  1 
ATOM   3345  C  CG  . HIS C 3 8   ? -12.712 9.437   37.039 1   108.15 ? 249 HIS P CG  1 
ATOM   3346  N  ND1 . HIS C 3 8   ? -12.85  8.075   37.234 1   108.25 ? 249 HIS P ND1 1 
ATOM   3347  C  CD2 . HIS C 3 8   ? -13.557 9.767   36.038 1   108.66 ? 249 HIS P CD2 1 
ATOM   3348  C  CE1 . HIS C 3 8   ? -13.747 7.603   36.393 1   110.37 ? 249 HIS P CE1 1 
ATOM   3349  N  NE2 . HIS C 3 8   ? -14.196 8.622   35.647 1   110.74 ? 249 HIS P NE2 1 
ATOM   3350  N  N   . ARG C 3 9   ? -9.344  10.347  40.106 1   91.78  ? 250 ARG P N   1 
ATOM   3351  C  CA  . ARG C 3 9   ? -8.257  11.097  40.797 1   86.36  ? 250 ARG P CA  1 
ATOM   3352  C  C   . ARG C 3 9   ? -8.139  12.511  40.226 1   82.1   ? 250 ARG P C   1 
ATOM   3353  O  O   . ARG C 3 9   ? -8.66   12.792  39.146 1   83.24  ? 250 ARG P O   1 
ATOM   3354  C  CB  . ARG C 3 9   ? -6.915  10.371  40.634 1   87.18  ? 250 ARG P CB  1 
ATOM   3355  C  CG  . ARG C 3 9   ? -6.398  10.308  39.199 1   87.29  ? 250 ARG P CG  1 
ATOM   3356  C  CD  . ARG C 3 9   ? -4.907  10.052  39.059 1   85.26  ? 250 ARG P CD  1 
ATOM   3357  N  NE  . ARG C 3 9   ? -4.096  10.941  39.889 1   80.94  ? 250 ARG P NE  1 
ATOM   3358  C  CZ  . ARG C 3 9   ? -3.421  10.597  40.99  1   79.85  ? 250 ARG P CZ  1 
ATOM   3359  N  NH1 . ARG C 3 9   ? -3.41   9.349   41.438 1   79.72  ? 250 ARG P NH1 1 
ATOM   3360  N  NH2 . ARG C 3 9   ? -2.736  11.519  41.645 1   79.3   ? 250 ARG P NH2 1 
ATOM   3361  N  N   . PRO C 3 10  ? -7.421  13.438  40.904 1   75.03  ? 251 PRO P N   1 
ATOM   3362  C  CA  . PRO C 3 10  ? -7.009  14.69   40.274 1   72.43  ? 251 PRO P CA  1 
ATOM   3363  C  C   . PRO C 3 10  ? -5.872  14.434  39.27  1   70.94  ? 251 PRO P C   1 
ATOM   3364  O  O   . PRO C 3 10  ? -5.163  13.444  39.411 1   67.91  ? 251 PRO P O   1 
ATOM   3365  C  CB  . PRO C 3 10  ? -6.543  15.597  41.426 1   73.52  ? 251 PRO P CB  1 
ATOM   3366  C  CG  . PRO C 3 10  ? -6.746  14.789  42.706 1   74.51  ? 251 PRO P CG  1 
ATOM   3367  C  CD  . PRO C 3 10  ? -6.967  13.346  42.299 1   74     ? 251 PRO P CD  1 
ATOM   3368  N  N   . ALA C 3 11  ? -5.733  15.329  38.287 1   70.6   ? 252 ALA P N   1 
ATOM   3369  C  CA  . ALA C 3 11  ? -4.665  15.317  37.259 1   67.28  ? 252 ALA P CA  1 
ATOM   3370  C  C   . ALA C 3 11  ? -3.301  15.384  37.951 1   65.52  ? 252 ALA P C   1 
ATOM   3371  O  O   . ALA C 3 11  ? -3.038  16.39   38.645 1   63.14  ? 252 ALA P O   1 
ATOM   3372  C  CB  . ALA C 3 11  ? -4.842  16.471  36.302 1   67.18  ? 252 ALA P CB  1 
ATOM   3373  N  N   . LEU C 3 12  ? -2.483  14.339  37.787 1   64.43  ? 253 LEU P N   1 
ATOM   3374  C  CA  . LEU C 3 12  ? -1.085  14.272  38.303 1   62.72  ? 253 LEU P CA  1 
ATOM   3375  C  C   . LEU C 3 12  ? -0.309  15.501  37.81  1   61.51  ? 253 LEU P C   1 
ATOM   3376  O  O   . LEU C 3 12  ? 0.417   16.106  38.625 1   58.38  ? 253 LEU P O   1 
ATOM   3377  C  CB  . LEU C 3 12  ? -0.442  12.965  37.824 1   59.47  ? 253 LEU P CB  1 
ATOM   3378  C  CG  . LEU C 3 12  ? 0.995   12.713  38.271 1   56.75  ? 253 LEU P CG  1 
ATOM   3379  C  CD1 . LEU C 3 12  ? 1.092   12.616  39.784 1   57.12  ? 253 LEU P CD1 1 
ATOM   3380  C  CD2 . LEU C 3 12  ? 1.533   11.447  37.629 1   57.94  ? 253 LEU P CD2 1 
ATOM   3381  N  N   . GLU C 3 13  ? -0.481  15.841  36.527 1   65.42  ? 254 GLU P N   1 
ATOM   3382  C  CA  . GLU C 3 13  ? 0.04    17.07   35.862 1   71.38  ? 254 GLU P CA  1 
ATOM   3383  C  C   . GLU C 3 13  ? -0.129  18.278  36.795 1   73.48  ? 254 GLU P C   1 
ATOM   3384  O  O   . GLU C 3 13  ? 0.892   18.91   37.126 1   76.49  ? 254 GLU P O   1 
ATOM   3385  C  CB  . GLU C 3 13  ? -0.675  17.279  34.524 1   74.98  ? 254 GLU P CB  1 
ATOM   3386  C  CG  . GLU C 3 13  ? 0.138   18.066  33.512 1   77.93  ? 254 GLU P CG  1 
ATOM   3387  C  CD  . GLU C 3 13  ? -0.401  18.035  32.089 1   83.57  ? 254 GLU P CD  1 
ATOM   3388  O  OE1 . GLU C 3 13  ? -0.954  16.988  31.679 1   84.93  ? 254 GLU P OE1 1 
ATOM   3389  O  OE2 . GLU C 3 13  ? -0.267  19.058  31.386 1   87.38  ? 254 GLU P OE2 1 
ATOM   3390  N  N   . ASP C 3 14  ? -1.36   18.543  37.247 1   74.7   ? 255 ASP P N   1 
ATOM   3391  C  CA  . ASP C 3 14  ? -1.72   19.699  38.117 1   73.6   ? 255 ASP P CA  1 
ATOM   3392  C  C   . ASP C 3 14  ? -1.043  19.567  39.49  1   69.64  ? 255 ASP P C   1 
ATOM   3393  O  O   . ASP C 3 14  ? -0.471  20.575  39.958 1   67.78  ? 255 ASP P O   1 
ATOM   3394  C  CB  . ASP C 3 14  ? -3.241  19.839  38.267 1   74.35  ? 255 ASP P CB  1 
ATOM   3395  C  CG  . ASP C 3 14  ? -3.991  20.129  36.974 1   76.15  ? 255 ASP P CG  1 
ATOM   3396  O  OD1 . ASP C 3 14  ? -3.353  20.571  35.995 1   77.7   ? 255 ASP P OD1 1 
ATOM   3397  O  OD2 . ASP C 3 14  ? -5.217  19.91   36.956 1   78.86  ? 255 ASP P OD2 1 
ATOM   3398  N  N   . LEU C 3 15  ? -1.096  18.38   40.105 1   63.95  ? 256 LEU P N   1 
ATOM   3399  C  CA  . LEU C 3 15  ? -0.609  18.13   41.492 1   63.48  ? 256 LEU P CA  1 
ATOM   3400  C  C   . LEU C 3 15  ? 0.913   18.306  41.585 1   61.18  ? 256 LEU P C   1 
ATOM   3401  O  O   . LEU C 3 15  ? 1.37    18.846  42.606 1   53.38  ? 256 LEU P O   1 
ATOM   3402  C  CB  . LEU C 3 15  ? -1.013  16.717  41.928 1   66.76  ? 256 LEU P CB  1 
ATOM   3403  C  CG  . LEU C 3 15  ? -2.507  16.49   42.153 1   66.26  ? 256 LEU P CG  1 
ATOM   3404  C  CD1 . LEU C 3 15  ? -2.821  15.005  42.165 1   67.36  ? 256 LEU P CD1 1 
ATOM   3405  C  CD2 . LEU C 3 15  ? -2.972  17.139  43.446 1   66.98  ? 256 LEU P CD2 1 
ATOM   3406  N  N   . LEU C 3 16  ? 1.669   17.843  40.582 1   65.51  ? 257 LEU P N   1 
ATOM   3407  C  CA  . LEU C 3 16  ? 3.161   17.853  40.598 1   67.29  ? 257 LEU P CA  1 
ATOM   3408  C  C   . LEU C 3 16  ? 3.684   19.273  40.343 1   68.33  ? 257 LEU P C   1 
ATOM   3409  O  O   . LEU C 3 16  ? 4.729   19.621  40.931 1   67.21  ? 257 LEU P O   1 
ATOM   3410  C  CB  . LEU C 3 16  ? 3.708   16.867  39.558 1   67.55  ? 257 LEU P CB  1 
ATOM   3411  C  CG  . LEU C 3 16  ? 3.526   15.381  39.871 1   65.25  ? 257 LEU P CG  1 
ATOM   3412  C  CD1 . LEU C 3 16  ? 3.966   14.536  38.688 1   65.15  ? 257 LEU P CD1 1 
ATOM   3413  C  CD2 . LEU C 3 16  ? 4.294   14.966  41.119 1   65.52  ? 257 LEU P CD2 1 
ATOM   3414  N  N   . LEU C 3 17  ? 2.994   20.052  39.502 1   70.06  ? 258 LEU P N   1 
ATOM   3415  C  CA  . LEU C 3 17  ? 3.286   21.494  39.263 1   74.27  ? 258 LEU P CA  1 
ATOM   3416  C  C   . LEU C 3 17  ? 3.054   22.315  40.542 1   77.46  ? 258 LEU P C   1 
ATOM   3417  O  O   . LEU C 3 17  ? 3.724   23.355  40.691 1   79.97  ? 258 LEU P O   1 
ATOM   3418  C  CB  . LEU C 3 17  ? 2.414   22.005  38.11  1   75.12  ? 258 LEU P CB  1 
ATOM   3419  C  CG  . LEU C 3 17  ? 2.765   21.46   36.725 1   75.95  ? 258 LEU P CG  1 
ATOM   3420  C  CD1 . LEU C 3 17  ? 1.634   21.711  35.738 1   77.77  ? 258 LEU P CD1 1 
ATOM   3421  C  CD2 . LEU C 3 17  ? 4.059   22.068  36.207 1   74.22  ? 258 LEU P CD2 1 
ATOM   3422  N  N   . GLY C 3 18  ? 2.145   21.88   41.425 1   80.87  ? 259 GLY P N   1 
ATOM   3423  C  CA  . GLY C 3 18  ? 1.828   22.552  42.703 1   80.87  ? 259 GLY P CA  1 
ATOM   3424  C  C   . GLY C 3 18  ? 0.789   23.647  42.521 1   83.78  ? 259 GLY P C   1 
ATOM   3425  O  O   . GLY C 3 18  ? 0.967   24.735  43.108 1   81.46  ? 259 GLY P O   1 
ATOM   3426  N  N   . SER C 3 19  ? -0.259  23.36   41.739 1   87.43  ? 260 SER P N   1 
ATOM   3427  C  CA  . SER C 3 19  ? -1.372  24.278  41.376 1   90.81  ? 260 SER P CA  1 
ATOM   3428  C  C   . SER C 3 19  ? -2.719  23.591  41.656 1   96.99  ? 260 SER P C   1 
ATOM   3429  O  O   . SER C 3 19  ? -2.701  22.426  42.114 1   100    ? 260 SER P O   1 
ATOM   3430  C  CB  . SER C 3 19  ? -1.242  24.707  39.934 1   89.7   ? 260 SER P CB  1 
ATOM   3431  O  OG  . SER C 3 19  ? -1.15   23.578  39.076 1   85.66  ? 260 SER P OG  1 
ATOM   3432  N  N   . GLU C 3 20  ? -3.837  24.288  41.408 1   99.17  ? 261 GLU P N   1 
ATOM   3433  C  CA  . GLU C 3 20  ? -5.225  23.799  41.656 1   100.12 ? 261 GLU P CA  1 
ATOM   3434  C  C   . GLU C 3 20  ? -5.521  22.587  40.76  1   97.53  ? 261 GLU P C   1 
ATOM   3435  O  O   . GLU C 3 20  ? -5.05   22.583  39.604 1   91.15  ? 261 GLU P O   1 
ATOM   3436  C  CB  . GLU C 3 20  ? -6.24   24.92   41.415 1   101.37 ? 261 GLU P CB  1 
ATOM   3437  C  CG  . GLU C 3 20  ? -6.152  26.048  42.422 0   104.1  ? 261 GLU P CG  1 
ATOM   3438  C  CD  . GLU C 3 20  ? -7.159  27.172  42.236 0   104.17 ? 261 GLU P CD  1 
ATOM   3439  O  OE1 . GLU C 3 20  ? -7.894  27.156  41.227 0   104.12 ? 261 GLU P OE1 1 
ATOM   3440  O  OE2 . GLU C 3 20  ? -7.207  28.065  43.105 0   104.09 ? 261 GLU P OE2 1 
ATOM   3441  N  N   . ALA C 3 21  ? -6.284  21.614  41.281 1   98.59  ? 262 ALA P N   1 
ATOM   3442  C  CA  . ALA C 3 21  ? -6.569  20.3    40.649 1   101.62 ? 262 ALA P CA  1 
ATOM   3443  C  C   . ALA C 3 21  ? -8.045  19.913  40.827 1   101.91 ? 262 ALA P C   1 
ATOM   3444  O  O   . ALA C 3 21  ? -8.542  19.979  41.969 1   97.53  ? 262 ALA P O   1 
ATOM   3445  C  CB  . ALA C 3 21  ? -5.662  19.252  41.244 1   104.15 ? 262 ALA P CB  1 
ATOM   3446  N  N   . ASN C 3 22  ? -8.697  19.486  39.736 1   105.17 ? 263 ASN P N   1 
ATOM   3447  C  CA  . ASN C 3 22  ? -10.13  19.082  39.679 1   103.01 ? 263 ASN P CA  1 
ATOM   3448  C  C   . ASN C 3 22  ? -10.266 17.591  40.013 1   104.77 ? 263 ASN P C   1 
ATOM   3449  O  O   . ASN C 3 22  ? -9.658  16.773  39.294 1   104.41 ? 263 ASN P O   1 
ATOM   3450  C  CB  . ASN C 3 22  ? -10.746 19.32   38.295 1   100.87 ? 263 ASN P CB  1 
ATOM   3451  C  CG  . ASN C 3 22  ? -10.675 20.76   37.828 1   100.8  ? 263 ASN P CG  1 
ATOM   3452  O  OD1 . ASN C 3 22  ? -10.841 21.683  38.623 1   103.46 ? 263 ASN P OD1 1 
ATOM   3453  N  ND2 . ASN C 3 22  ? -10.452 20.964  36.538 1   98.1   ? 263 ASN P ND2 1 
ATOM   3454  N  N   . LEU C 3 23  ? -11.046 17.252  41.045 1   106.37 ? 264 LEU P N   1 
ATOM   3455  C  CA  . LEU C 3 23  ? -11.515 15.866  41.326 1   108.35 ? 264 LEU P CA  1 
ATOM   3456  C  C   . LEU C 3 23  ? -12.892 15.685  40.671 1   109.33 ? 264 LEU P C   1 
ATOM   3457  O  O   . LEU C 3 23  ? -13.787 16.5    40.965 1   110.73 ? 264 LEU P O   1 
ATOM   3458  C  CB  . LEU C 3 23  ? -11.568 15.645  42.843 1   106.27 ? 264 LEU P CB  1 
ATOM   3459  C  CG  . LEU C 3 23  ? -11.661 14.188  43.296 1   104    ? 264 LEU P CG  1 
ATOM   3460  C  CD1 . LEU C 3 23  ? -10.763 13.971  44.545 0   103.86 ? 264 LEU P CD1 1 
ATOM   3461  C  CD2 . LEU C 3 23  ? -13.028 13.719  43.529 0   103.99 ? 264 LEU P CD2 1 
ATOM   3462  N  N   . THR C 3 24  ? -13.042 14.676  39.805 1   113.43 ? 265 THR P N   1 
ATOM   3463  C  CA  . THR C 3 24  ? -14.235 14.447  38.938 1   116.66 ? 265 THR P CA  1 
ATOM   3464  C  C   . THR C 3 24  ? -15.077 13.294  39.502 1   120.15 ? 265 THR P C   1 
ATOM   3465  O  O   . THR C 3 24  ? -14.489 12.3    39.983 1   118.85 ? 265 THR P O   1 
ATOM   3466  C  CB  . THR C 3 24  ? -13.809 14.218  37.48  1   114.61 ? 265 THR P CB  1 
ATOM   3467  O  OG1 . THR C 3 24  ? -13.345 15.475  36.986 1   114.54 ? 265 THR P OG1 1 
ATOM   3468  C  CG2 . THR C 3 24  ? -14.913 13.702  36.582 1   110.41 ? 265 THR P CG2 1 
ATOM   3469  N  N   . CYS C 3 25  ? -16.406 13.433  39.415 1   123.04 ? 266 CYS P N   1 
ATOM   3470  C  CA  . CYS C 3 25  ? -17.43  12.458  39.877 1   125.43 ? 266 CYS P CA  1 
ATOM   3471  C  C   . CYS C 3 25  ? -18.46  12.256  38.761 1   126.28 ? 266 CYS P C   1 
ATOM   3472  O  O   . CYS C 3 25  ? -19.113 13.251  38.38  1   122.63 ? 266 CYS P O   1 
ATOM   3473  C  CB  . CYS C 3 25  ? -18.095 12.956  41.154 1   124.67 ? 266 CYS P CB  1 
ATOM   3474  S  SG  . CYS C 3 25  ? -19.281 11.798  41.885 1   124.35 ? 266 CYS P SG  1 
ATOM   3475  N  N   . THR C 3 26  ? -18.587 11.02   38.263 1   130.91 ? 267 THR P N   1 
ATOM   3476  C  CA  . THR C 3 26  ? -19.395 10.654  37.067 1   136.92 ? 267 THR P CA  1 
ATOM   3477  C  C   . THR C 3 26  ? -20.298 9.453   37.382 1   139.97 ? 267 THR P C   1 
ATOM   3478  O  O   . THR C 3 26  ? -19.854 8.567   38.145 1   135.34 ? 267 THR P O   1 
ATOM   3479  C  CB  . THR C 3 26  ? -18.487 10.374  35.861 1   136.31 ? 267 THR P CB  1 
ATOM   3480  O  OG1 . THR C 3 26  ? -17.544 9.365   36.224 1   140.28 ? 267 THR P OG1 1 
ATOM   3481  C  CG2 . THR C 3 26  ? -17.744 11.603  35.387 1   134.06 ? 267 THR P CG2 1 
ATOM   3482  N  N   . LEU C 3 27  ? -21.504 9.437   36.795 1   141.39 ? 268 LEU P N   1 
ATOM   3483  C  CA  . LEU C 3 27  ? -22.519 8.352   36.899 1   139.23 ? 268 LEU P CA  1 
ATOM   3484  C  C   . LEU C 3 27  ? -22.684 7.695   35.52  1   138.71 ? 268 LEU P C   1 
ATOM   3485  O  O   . LEU C 3 27  ? -23.521 8.175   34.732 1   134.36 ? 268 LEU P O   1 
ATOM   3486  C  CB  . LEU C 3 27  ? -23.829 8.96    37.416 1   136.58 ? 268 LEU P CB  1 
ATOM   3487  C  CG  . LEU C 3 27  ? -24.96  7.968   37.688 1   135.32 ? 268 LEU P CG  1 
ATOM   3488  C  CD1 . LEU C 3 27  ? -24.705 7.085   38.84  0   147.45 ? 268 LEU P CD1 1 
ATOM   3489  C  CD2 . LEU C 3 27  ? -26.278 8.787   37.915 0   147.5  ? 268 LEU P CD2 1 
ATOM   3490  N  N   . THR C 3 28  ? -21.911 6.634   35.254 1   141.56 ? 269 THR P N   1 
ATOM   3491  C  CA  . THR C 3 28  ? -21.767 5.957   33.931 1   144.09 ? 269 THR P CA  1 
ATOM   3492  C  C   . THR C 3 28  ? -23.074 5.265   33.523 1   146.9  ? 269 THR P C   1 
ATOM   3493  O  O   . THR C 3 28  ? -23.364 5.252   32.311 1   144.28 ? 269 THR P O   1 
ATOM   3494  C  CB  . THR C 3 28  ? -20.614 4.944   33.944 1   141.07 ? 269 THR P CB  1 
ATOM   3495  O  OG1 . THR C 3 28  ? -20.775 4.067   35.012 0   150.69 ? 269 THR P OG1 1 
ATOM   3496  C  CG2 . THR C 3 28  ? -19.259 5.646   34.016 0   150.53 ? 269 THR P CG2 1 
ATOM   3497  N  N   . GLY C 3 29  ? -23.794 4.676   34.487 1   150.49 ? 270 GLY P N   1 
ATOM   3498  C  CA  . GLY C 3 29  ? -25.151 4.12    34.314 1   147.62 ? 270 GLY P CA  1 
ATOM   3499  C  C   . GLY C 3 29  ? -25.196 3.007   33.282 1   147.7  ? 270 GLY P C   1 
ATOM   3500  O  O   . GLY C 3 29  ? -26.096 3.072   32.422 1   147.57 ? 270 GLY P O   1 
ATOM   3501  N  N   . VAL C 3 36  ? -30.187 16.475  37.93  1   136.24 ? 277 VAL P N   1 
ATOM   3502  C  CA  . VAL C 3 36  ? -29.452 15.738  39.004 1   135.92 ? 277 VAL P CA  1 
ATOM   3503  C  C   . VAL C 3 36  ? -28.54  16.714  39.761 1   137.78 ? 277 VAL P C   1 
ATOM   3504  O  O   . VAL C 3 36  ? -28     17.637  39.115 1   143.87 ? 277 VAL P O   1 
ATOM   3505  C  CB  . VAL C 3 36  ? -28.645 14.557  38.429 1   130.98 ? 277 VAL P CB  1 
ATOM   3506  C  CG1 . VAL C 3 36  ? -29.505 13.503  37.795 0   145    ? 277 VAL P CG1 1 
ATOM   3507  C  CG2 . VAL C 3 36  ? -27.527 14.991  37.471 0   145.01 ? 277 VAL P CG2 1 
ATOM   3508  N  N   . THR C 3 37  ? -28.38  16.51   41.074 1   136.08 ? 278 THR P N   1 
ATOM   3509  C  CA  . THR C 3 37  ? -27.476 17.286  41.972 1   135.06 ? 278 THR P CA  1 
ATOM   3510  C  C   . THR C 3 37  ? -26.647 16.305  42.811 1   135.4  ? 278 THR P C   1 
ATOM   3511  O  O   . THR C 3 37  ? -27.213 15.277  43.243 1   137.69 ? 278 THR P O   1 
ATOM   3512  C  CB  . THR C 3 37  ? -28.267 18.269  42.848 1   134.52 ? 278 THR P CB  1 
ATOM   3513  O  OG1 . THR C 3 37  ? -29.113 19.041  41.995 1   132.73 ? 278 THR P OG1 1 
ATOM   3514  C  CG2 . THR C 3 37  ? -27.386 19.204  43.65  1   134.11 ? 278 THR P CG2 1 
ATOM   3515  N  N   . PHE C 3 38  ? -25.362 16.618  43.021 1   130.39 ? 279 PHE P N   1 
ATOM   3516  C  CA  . PHE C 3 38  ? -24.397 15.841  43.846 1   120.84 ? 279 PHE P CA  1 
ATOM   3517  C  C   . PHE C 3 38  ? -24.158 16.562  45.176 1   115.23 ? 279 PHE P C   1 
ATOM   3518  O  O   . PHE C 3 38  ? -24.433 17.776  45.266 1   113.59 ? 279 PHE P O   1 
ATOM   3519  C  CB  . PHE C 3 38  ? -23.056 15.673  43.126 1   119.94 ? 279 PHE P CB  1 
ATOM   3520  C  CG  . PHE C 3 38  ? -23.122 15.02   41.769 1   120.59 ? 279 PHE P CG  1 
ATOM   3521  C  CD1 . PHE C 3 38  ? -23.435 15.764  40.642 1   120.29 ? 279 PHE P CD1 1 
ATOM   3522  C  CD2 . PHE C 3 38  ? -22.851 13.669  41.61  1   122.01 ? 279 PHE P CD2 1 
ATOM   3523  C  CE1 . PHE C 3 38  ? -23.492 15.171  39.388 1   121.33 ? 279 PHE P CE1 1 
ATOM   3524  C  CE2 . PHE C 3 38  ? -22.906 13.076  40.355 1   123.36 ? 279 PHE P CE2 1 
ATOM   3525  C  CZ  . PHE C 3 38  ? -23.225 13.828  39.246 1   121.79 ? 279 PHE P CZ  1 
ATOM   3526  N  N   . THR C 3 39  ? -23.649 15.828  46.169 1   112.81 ? 280 THR P N   1 
ATOM   3527  C  CA  . THR C 3 39  ? -23.133 16.361  47.461 1   112.93 ? 280 THR P CA  1 
ATOM   3528  C  C   . THR C 3 39  ? -21.775 15.712  47.75  1   110    ? 280 THR P C   1 
ATOM   3529  O  O   . THR C 3 39  ? -21.609 14.519  47.415 1   104.51 ? 280 THR P O   1 
ATOM   3530  C  CB  . THR C 3 39  ? -24.141 16.15   48.6   1   114.1  ? 280 THR P CB  1 
ATOM   3531  O  OG1 . THR C 3 39  ? -25.363 16.784  48.221 1   116.04 ? 280 THR P OG1 1 
ATOM   3532  C  CG2 . THR C 3 39  ? -23.679 16.711  49.929 1   112.81 ? 280 THR P CG2 1 
ATOM   3533  N  N   . TRP C 3 40  ? -20.856 16.479  48.348 1   111.5  ? 281 TRP P N   1 
ATOM   3534  C  CA  . TRP C 3 40  ? -19.459 16.075  48.666 1   112.6  ? 281 TRP P CA  1 
ATOM   3535  C  C   . TRP C 3 40  ? -19.222 16.214  50.176 1   114.45 ? 281 TRP P C   1 
ATOM   3536  O  O   . TRP C 3 40  ? -19.629 17.252  50.739 1   107.36 ? 281 TRP P O   1 
ATOM   3537  C  CB  . TRP C 3 40  ? -18.443 16.908  47.868 1   109.34 ? 281 TRP P CB  1 
ATOM   3538  C  CG  . TRP C 3 40  ? -18.739 17.067  46.405 1   105.86 ? 281 TRP P CG  1 
ATOM   3539  C  CD1 . TRP C 3 40  ? -19.716 17.836  45.841 1   104.52 ? 281 TRP P CD1 1 
ATOM   3540  C  CD2 . TRP C 3 40  ? -18.016 16.478  45.309 1   102.49 ? 281 TRP P CD2 1 
ATOM   3541  N  NE1 . TRP C 3 40  ? -19.667 17.748  44.476 1   102.8  ? 281 TRP P NE1 1 
ATOM   3542  C  CE2 . TRP C 3 40  ? -18.634 16.925  44.119 1   101.69 ? 281 TRP P CE2 1 
ATOM   3543  C  CE3 . TRP C 3 40  ? -16.917 15.614  45.215 1   101    ? 281 TRP P CE3 1 
ATOM   3544  C  CZ2 . TRP C 3 40  ? -18.187 16.535  42.856 1   102.37 ? 281 TRP P CZ2 1 
ATOM   3545  C  CZ3 . TRP C 3 40  ? -16.476 15.23   43.966 1   101.63 ? 281 TRP P CZ3 1 
ATOM   3546  C  CH2 . TRP C 3 40  ? -17.103 15.688  42.805 1   102.8  ? 281 TRP P CH2 1 
ATOM   3547  N  N   . THR C 3 41  ? -18.584 15.214  50.796 1   120.88 ? 282 THR P N   1 
ATOM   3548  C  CA  . THR C 3 41  ? -18.216 15.197  52.241 1   125.71 ? 282 THR P CA  1 
ATOM   3549  C  C   . THR C 3 41  ? -17.151 16.258  52.521 1   129.14 ? 282 THR P C   1 
ATOM   3550  O  O   . THR C 3 41  ? -17.385 17.143  53.343 1   134.96 ? 282 THR P O   1 
ATOM   3551  C  CB  . THR C 3 41  ? -17.811 13.789  52.706 1   127.76 ? 282 THR P CB  1 
ATOM   3552  O  OG1 . THR C 3 41  ? -19     13      52.704 1   130.7  ? 282 THR P OG1 1 
ATOM   3553  C  CG2 . THR C 3 41  ? -17.195 13.741  54.09  1   127.53 ? 282 THR P CG2 1 
ATOM   3554  N  N   . PRO C 3 42  ? -15.964 16.231  51.862 1   127.08 ? 283 PRO P N   1 
ATOM   3555  C  CA  . PRO C 3 42  ? -14.853 17.105  52.252 1   124.42 ? 283 PRO P CA  1 
ATOM   3556  C  C   . PRO C 3 42  ? -14.942 18.56   51.758 1   125.23 ? 283 PRO P C   1 
ATOM   3557  O  O   . PRO C 3 42  ? -14.072 19.328  52.124 1   125.02 ? 283 PRO P O   1 
ATOM   3558  C  CB  . PRO C 3 42  ? -13.653 16.406  51.603 1   122.43 ? 283 PRO P CB  1 
ATOM   3559  C  CG  . PRO C 3 42  ? -14.228 15.85   50.327 1   124.91 ? 283 PRO P CG  1 
ATOM   3560  C  CD  . PRO C 3 42  ? -15.625 15.397  50.697 1   123.53 ? 283 PRO P CD  1 
ATOM   3561  N  N   . SER C 3 43  ? -15.959 18.899  50.954 1   130.4  ? 284 SER P N   1 
ATOM   3562  C  CA  . SER C 3 43  ? -16.225 20.272  50.443 1   136.38 ? 284 SER P CA  1 
ATOM   3563  C  C   . SER C 3 43  ? -16.587 21.203  51.608 1   140.17 ? 284 SER P C   1 
ATOM   3564  O  O   . SER C 3 43  ? -17.602 20.93   52.281 1   135.8  ? 284 SER P O   1 
ATOM   3565  C  CB  . SER C 3 43  ? -17.313 20.267  49.397 1   136.49 ? 284 SER P CB  1 
ATOM   3566  O  OG  . SER C 3 43  ? -18.542 19.806  49.942 1   135.79 ? 284 SER P OG  1 
ATOM   3567  N  N   . SER C 3 44  ? -15.781 22.249  51.831 1   146.28 ? 285 SER P N   1 
ATOM   3568  C  CA  . SER C 3 44  ? -15.995 23.314  52.847 1   151.56 ? 285 SER P CA  1 
ATOM   3569  C  C   . SER C 3 44  ? -16.152 24.663  52.132 1   155.02 ? 285 SER P C   1 
ATOM   3570  O  O   . SER C 3 44  ? -15.266 25.533  52.283 1   158    ? 285 SER P O   1 
ATOM   3571  C  CB  . SER C 3 44  ? -14.875 23.327  53.861 1   150.24 ? 285 SER P CB  1 
ATOM   3572  O  OG  . SER C 3 44  ? -14.822 22.094  54.561 0   157.47 ? 285 SER P OG  1 
ATOM   3573  N  N   . GLY C 3 45  ? -17.245 24.812  51.374 1   155.52 ? 286 GLY P N   1 
ATOM   3574  C  CA  . GLY C 3 45  ? -17.542 25.987  50.53  1   152.91 ? 286 GLY P CA  1 
ATOM   3575  C  C   . GLY C 3 45  ? -16.947 25.866  49.134 1   150.36 ? 286 GLY P C   1 
ATOM   3576  O  O   . GLY C 3 45  ? -16.848 26.907  48.454 1   149.68 ? 286 GLY P O   1 
ATOM   3577  N  N   . LYS C 3 46  ? -16.57  24.651  48.716 1   147.07 ? 287 LYS P N   1 
ATOM   3578  C  CA  . LYS C 3 46  ? -16.046 24.349  47.355 1   141.69 ? 287 LYS P CA  1 
ATOM   3579  C  C   . LYS C 3 46  ? -17.229 24.29   46.38  1   136.36 ? 287 LYS P C   1 
ATOM   3580  O  O   . LYS C 3 46  ? -18.024 23.332  46.471 1   133.38 ? 287 LYS P O   1 
ATOM   3581  C  CB  . LYS C 3 46  ? -15.254 23.036  47.364 1   141.24 ? 287 LYS P CB  1 
ATOM   3582  C  CG  . LYS C 3 46  ? -14.03  23.002  48.25  0   145.57 ? 287 LYS P CG  1 
ATOM   3583  C  CD  . LYS C 3 46  ? -13.32  21.664  48.26  0   145.32 ? 287 LYS P CD  1 
ATOM   3584  C  CE  . LYS C 3 46  ? -12.484 21.447  49.503 0   145.12 ? 287 LYS P CE  1 
ATOM   3585  N  NZ  . LYS C 3 46  ? -12.147 20.016  49.696 0   145.01 ? 287 LYS P NZ  1 
ATOM   3586  N  N   . SER C 3 47  ? -17.344 25.285  45.493 1   131.97 ? 288 SER P N   1 
ATOM   3587  C  CA  . SER C 3 47  ? -18.464 25.444  44.526 1   130.05 ? 288 SER P CA  1 
ATOM   3588  C  C   . SER C 3 47  ? -18.337 24.407  43.401 1   130.74 ? 288 SER P C   1 
ATOM   3589  O  O   . SER C 3 47  ? -17.533 24.631  42.47  1   126.58 ? 288 SER P O   1 
ATOM   3590  C  CB  . SER C 3 47  ? -18.526 26.857  43.988 1   127.62 ? 288 SER P CB  1 
ATOM   3591  O  OG  . SER C 3 47  ? -17.248 27.298  43.554 1   124.08 ? 288 SER P OG  1 
ATOM   3592  N  N   . ALA C 3 48  ? -19.104 23.312  43.493 1   131.6  ? 289 ALA P N   1 
ATOM   3593  C  CA  . ALA C 3 48  ? -19.183 22.223  42.487 1   132.85 ? 289 ALA P CA  1 
ATOM   3594  C  C   . ALA C 3 48  ? -19.818 22.754  41.194 1   132.14 ? 289 ALA P C   1 
ATOM   3595  O  O   . ALA C 3 48  ? -20.667 23.662  41.282 1   134.66 ? 289 ALA P O   1 
ATOM   3596  C  CB  . ALA C 3 48  ? -19.965 21.056  43.043 1   132.99 ? 289 ALA P CB  1 
ATOM   3597  N  N   . VAL C 3 49  ? -19.418 22.197  40.044 1   132.04 ? 290 VAL P N   1 
ATOM   3598  C  CA  . VAL C 3 49  ? -19.828 22.649  38.678 1   135.57 ? 290 VAL P CA  1 
ATOM   3599  C  C   . VAL C 3 49  ? -20.226 21.416  37.852 1   138.33 ? 290 VAL P C   1 
ATOM   3600  O  O   . VAL C 3 49  ? -19.453 20.438  37.857 1   139.5  ? 290 VAL P O   1 
ATOM   3601  C  CB  . VAL C 3 49  ? -18.697 23.455  38.001 1   134.45 ? 290 VAL P CB  1 
ATOM   3602  C  CG1 . VAL C 3 49  ? -19.072 23.929  36.603 1   134.43 ? 290 VAL P CG1 1 
ATOM   3603  C  CG2 . VAL C 3 49  ? -18.256 24.64   38.851 1   132.25 ? 290 VAL P CG2 1 
ATOM   3604  N  N   . GLN C 3 50  ? -21.377 21.475  37.167 1   139.35 ? 291 GLN P N   1 
ATOM   3605  C  CA  . GLN C 3 50  ? -21.923 20.399  36.29  1   141.2  ? 291 GLN P CA  1 
ATOM   3606  C  C   . GLN C 3 50  ? -21.804 20.81   34.817 1   142.28 ? 291 GLN P C   1 
ATOM   3607  O  O   . GLN C 3 50  ? -21.465 21.983  34.553 1   139.97 ? 291 GLN P O   1 
ATOM   3608  C  CB  . GLN C 3 50  ? -23.391 20.129  36.623 1   142.8  ? 291 GLN P CB  1 
ATOM   3609  C  CG  . GLN C 3 50  ? -23.611 19.513  37.995 1   143.54 ? 291 GLN P CG  1 
ATOM   3610  C  CD  . GLN C 3 50  ? -25.062 19.178  38.242 1   141.85 ? 291 GLN P CD  1 
ATOM   3611  O  OE1 . GLN C 3 50  ? -25.965 19.676  37.573 1   141.21 ? 291 GLN P OE1 1 
ATOM   3612  N  NE2 . GLN C 3 50  ? -25.302 18.325  39.221 1   140.6  ? 291 GLN P NE2 1 
ATOM   3613  N  N   . GLY C 3 51  ? -22.091 19.874  33.903 1   143.72 ? 292 GLY P N   1 
ATOM   3614  C  CA  . GLY C 3 51  ? -22.089 20.085  32.44  1   145.56 ? 292 GLY P CA  1 
ATOM   3615  C  C   . GLY C 3 51  ? -23.271 19.396  31.758 1   148.47 ? 292 GLY P C   1 
ATOM   3616  O  O   . GLY C 3 51  ? -24.138 18.845  32.436 1   148.12 ? 292 GLY P O   1 
ATOM   3617  N  N   . PRO C 3 52  ? -23.355 19.43   30.404 1   151.89 ? 293 PRO P N   1 
ATOM   3618  C  CA  . PRO C 3 52  ? -24.394 18.705  29.665 1   154.24 ? 293 PRO P CA  1 
ATOM   3619  C  C   . PRO C 3 52  ? -24.222 17.186  29.74  1   155.74 ? 293 PRO P C   1 
ATOM   3620  O  O   . PRO C 3 52  ? -23.114 16.689  29.543 1   156.75 ? 293 PRO P O   1 
ATOM   3621  C  CB  . PRO C 3 52  ? -24.23  19.177  28.208 1   151.9  ? 293 PRO P CB  1 
ATOM   3622  C  CG  . PRO C 3 52  ? -23.371 20.423  28.296 1   150.26 ? 293 PRO P CG  1 
ATOM   3623  C  CD  . PRO C 3 52  ? -22.489 20.21   29.507 1   150.24 ? 293 PRO P CD  1 
ATOM   3624  N  N   . PRO C 3 53  ? -25.297 16.402  30.006 1   155.63 ? 294 PRO P N   1 
ATOM   3625  C  CA  . PRO C 3 53  ? -25.18  14.948  30.152 1   153.09 ? 294 PRO P CA  1 
ATOM   3626  C  C   . PRO C 3 53  ? -25.14  14.203  28.806 1   151.24 ? 294 PRO P C   1 
ATOM   3627  O  O   . PRO C 3 53  ? -26.081 14.339  28.043 1   156.28 ? 294 PRO P O   1 
ATOM   3628  C  CB  . PRO C 3 53  ? -26.445 14.604  30.953 1   152.2  ? 294 PRO P CB  1 
ATOM   3629  C  CG  . PRO C 3 53  ? -27.475 15.608  30.479 1   151.55 ? 294 PRO P CG  1 
ATOM   3630  C  CD  . PRO C 3 53  ? -26.685 16.866  30.182 1   153.42 ? 294 PRO P CD  1 
ATOM   3631  N  N   . GLU C 3 54  ? -24.066 13.446  28.546 1   143.7  ? 295 GLU P N   1 
ATOM   3632  C  CA  . GLU C 3 54  ? -23.873 12.655  27.296 1   138.36 ? 295 GLU P CA  1 
ATOM   3633  C  C   . GLU C 3 54  ? -23.065 11.387  27.603 1   133.99 ? 295 GLU P C   1 
ATOM   3634  O  O   . GLU C 3 54  ? -21.842 11.518  27.798 1   131.15 ? 295 GLU P O   1 
ATOM   3635  C  CB  . GLU C 3 54  ? -23.186 13.511  26.229 1   137.65 ? 295 GLU P CB  1 
ATOM   3636  C  CG  . GLU C 3 54  ? -24.123 14.515  25.567 0   145    ? 295 GLU P CG  1 
ATOM   3637  C  CD  . GLU C 3 54  ? -23.579 15.196  24.321 0   144.87 ? 295 GLU P CD  1 
ATOM   3638  O  OE1 . GLU C 3 54  ? -22.346 15.191  24.129 0   144.77 ? 295 GLU P OE1 1 
ATOM   3639  O  OE2 . GLU C 3 54  ? -24.394 15.732  23.544 0   144.74 ? 295 GLU P OE2 1 
ATOM   3640  N  N   . CYS C 3 58  ? -20.884 4.04    24.35  1   139.42 ? 299 CYS P N   1 
ATOM   3641  C  CA  . CYS C 3 58  ? -22.313 3.646   24.516 1   141.06 ? 299 CYS P CA  1 
ATOM   3642  C  C   . CYS C 3 58  ? -23.23  4.843   24.224 1   140.84 ? 299 CYS P C   1 
ATOM   3643  O  O   . CYS C 3 58  ? -24.094 4.719   23.329 1   136.49 ? 299 CYS P O   1 
ATOM   3644  C  CB  . CYS C 3 58  ? -22.581 3.106   25.919 1   145.45 ? 299 CYS P CB  1 
ATOM   3645  S  SG  . CYS C 3 58  ? -24.226 2.369   26.124 1   151.69 ? 299 CYS P SG  1 
ATOM   3646  N  N   . GLY C 3 59  ? -23.035 5.952   24.948 1   138.52 ? 300 GLY P N   1 
ATOM   3647  C  CA  . GLY C 3 59  ? -23.903 7.146   24.914 1   136.69 ? 300 GLY P CA  1 
ATOM   3648  C  C   . GLY C 3 59  ? -25.221 6.896   25.629 1   137.5  ? 300 GLY P C   1 
ATOM   3649  O  O   . GLY C 3 59  ? -26.251 7.409   25.151 1   131.28 ? 300 GLY P O   1 
ATOM   3650  N  N   . CYS C 3 60  ? -25.183 6.154   26.744 1   144.24 ? 301 CYS P N   1 
ATOM   3651  C  CA  . CYS C 3 60  ? -26.366 5.62    27.477 1   149.29 ? 301 CYS P CA  1 
ATOM   3652  C  C   . CYS C 3 60  ? -26.333 6.067   28.948 1   153.03 ? 301 CYS P C   1 
ATOM   3653  O  O   . CYS C 3 60  ? -25.887 5.275   29.805 1   158.01 ? 301 CYS P O   1 
ATOM   3654  C  CB  . CYS C 3 60  ? -26.443 4.098   27.349 1   150.65 ? 301 CYS P CB  1 
ATOM   3655  S  SG  . CYS C 3 60  ? -24.937 3.213   27.84  1   156.16 ? 301 CYS P SG  1 
ATOM   3656  N  N   . TYR C 3 61  ? -26.788 7.3     29.214 1   153.46 ? 302 TYR P N   1 
ATOM   3657  C  CA  . TYR C 3 61  ? -27.049 7.878   30.563 1   156.41 ? 302 TYR P CA  1 
ATOM   3658  C  C   . TYR C 3 61  ? -25.726 8.126   31.309 1   158.94 ? 302 TYR P C   1 
ATOM   3659  O  O   . TYR C 3 61  ? -25.318 7.261   32.112 1   162.69 ? 302 TYR P O   1 
ATOM   3660  C  CB  . TYR C 3 61  ? -28.015 6.98    31.345 1   155.68 ? 302 TYR P CB  1 
ATOM   3661  C  CG  . TYR C 3 61  ? -28.629 7.489   32.58  0   164.78 ? 302 TYR P CG  1 
ATOM   3662  C  CD1 . TYR C 3 61  ? -29.759 8.287   32.522 0   164.75 ? 302 TYR P CD1 1 
ATOM   3663  C  CD2 . TYR C 3 61  ? -28.116 7.186   33.831 0   164.79 ? 302 TYR P CD2 1 
ATOM   3664  C  CE1 . TYR C 3 61  ? -30.35  8.79    33.669 0   164.68 ? 302 TYR P CE1 1 
ATOM   3665  C  CE2 . TYR C 3 61  ? -28.694 7.68    34.988 0   164.69 ? 302 TYR P CE2 1 
ATOM   3666  C  CZ  . TYR C 3 61  ? -29.815 8.485   34.908 0   164.71 ? 302 TYR P CZ  1 
ATOM   3667  O  OH  . TYR C 3 61  ? -30.39  8.977   36.044 0   164.72 ? 302 TYR P OH  1 
ATOM   3668  N  N   . SER C 3 62  ? -25.093 9.285   31.069 1   155.48 ? 303 SER P N   1 
ATOM   3669  C  CA  . SER C 3 62  ? -23.805 9.719   31.684 1   148.91 ? 303 SER P CA  1 
ATOM   3670  C  C   . SER C 3 62  ? -23.843 11.213  32.047 1   146.82 ? 303 SER P C   1 
ATOM   3671  O  O   . SER C 3 62  ? -24.086 12.032  31.136 1   147.03 ? 303 SER P O   1 
ATOM   3672  C  CB  . SER C 3 62  ? -22.644 9.407   30.772 1   144.92 ? 303 SER P CB  1 
ATOM   3673  O  OG  . SER C 3 62  ? -22.344 8.02    30.788 1   139.63 ? 303 SER P OG  1 
ATOM   3674  N  N   . VAL C 3 63  ? -23.596 11.545  33.323 1   142.3  ? 304 VAL P N   1 
ATOM   3675  C  CA  . VAL C 3 63  ? -23.524 12.939  33.869 1   141.4  ? 304 VAL P CA  1 
ATOM   3676  C  C   . VAL C 3 63  ? -22.207 13.089  34.644 1   142.36 ? 304 VAL P C   1 
ATOM   3677  O  O   . VAL C 3 63  ? -21.754 12.077  35.214 1   145.81 ? 304 VAL P O   1 
ATOM   3678  C  CB  . VAL C 3 63  ? -24.728 13.274  34.775 1   139.4  ? 304 VAL P CB  1 
ATOM   3679  C  CG1 . VAL C 3 63  ? -24.848 14.773  35.019 1   136.31 ? 304 VAL P CG1 1 
ATOM   3680  C  CG2 . VAL C 3 63  ? -26.038 12.721  34.232 1   140.13 ? 304 VAL P CG2 1 
ATOM   3681  N  N   . SER C 3 64  ? -21.645 14.306  34.684 1   138.8  ? 305 SER P N   1 
ATOM   3682  C  CA  . SER C 3 64  ? -20.338 14.645  35.315 1   132.87 ? 305 SER P CA  1 
ATOM   3683  C  C   . SER C 3 64  ? -20.464 15.884  36.215 1   128.46 ? 305 SER P C   1 
ATOM   3684  O  O   . SER C 3 64  ? -21.245 16.796  35.863 1   126.38 ? 305 SER P O   1 
ATOM   3685  C  CB  . SER C 3 64  ? -19.282 14.854  34.26  1   130.56 ? 305 SER P CB  1 
ATOM   3686  O  OG  . SER C 3 64  ? -19.637 15.904  33.383 0   133.11 ? 305 SER P OG  1 
ATOM   3687  N  N   . SER C 3 65  ? -19.712 15.911  37.324 1   122.77 ? 306 SER P N   1 
ATOM   3688  C  CA  . SER C 3 65  ? -19.601 17.055  38.273 1   118.44 ? 306 SER P CA  1 
ATOM   3689  C  C   . SER C 3 65  ? -18.182 17.14   38.852 1   117.77 ? 306 SER P C   1 
ATOM   3690  O  O   . SER C 3 65  ? -17.741 16.149  39.471 1   117.95 ? 306 SER P O   1 
ATOM   3691  C  CB  . SER C 3 65  ? -20.623 16.952  39.373 1   116.38 ? 306 SER P CB  1 
ATOM   3692  O  OG  . SER C 3 65  ? -20.364 17.897  40.402 1   113.77 ? 306 SER P OG  1 
ATOM   3693  N  N   . VAL C 3 66  ? -17.522 18.294  38.686 1   116.73 ? 307 VAL P N   1 
ATOM   3694  C  CA  . VAL C 3 66  ? -16.126 18.572  39.151 1   115.49 ? 307 VAL P CA  1 
ATOM   3695  C  C   . VAL C 3 66  ? -16.181 19.328  40.487 1   113.65 ? 307 VAL P C   1 
ATOM   3696  O  O   . VAL C 3 66  ? -17.24  19.916  40.798 1   115.02 ? 307 VAL P O   1 
ATOM   3697  C  CB  . VAL C 3 66  ? -15.299 19.34   38.094 1   115.78 ? 307 VAL P CB  1 
ATOM   3698  C  CG1 . VAL C 3 66  ? -15.26  18.603  36.763 1   115.08 ? 307 VAL P CG1 1 
ATOM   3699  C  CG2 . VAL C 3 66  ? -15.762 20.779  37.887 1   115.06 ? 307 VAL P CG2 1 
ATOM   3700  N  N   . LEU C 3 67  ? -15.07  19.307  41.234 1   110.99 ? 308 LEU P N   1 
ATOM   3701  C  CA  . LEU C 3 67  ? -14.878 20.027  42.525 1   107.81 ? 308 LEU P CA  1 
ATOM   3702  C  C   . LEU C 3 67  ? -13.467 20.617  42.562 1   108.83 ? 308 LEU P C   1 
ATOM   3703  O  O   . LEU C 3 67  ? -12.503 19.883  42.772 1   110.81 ? 308 LEU P O   1 
ATOM   3704  C  CB  . LEU C 3 67  ? -15.099 19.046  43.682 1   103.36 ? 308 LEU P CB  1 
ATOM   3705  C  CG  . LEU C 3 67  ? -15.174 19.679  45.071 1   101.65 ? 308 LEU P CG  1 
ATOM   3706  C  CD1 . LEU C 3 67  ? -16.547 20.291  45.306 1   103.84 ? 308 LEU P CD1 1 
ATOM   3707  C  CD2 . LEU C 3 67  ? -14.85  18.664  46.156 1   101.48 ? 308 LEU P CD2 1 
ATOM   3708  N  N   . PRO C 3 68  ? -13.292 21.948  42.364 1   108.32 ? 309 PRO P N   1 
ATOM   3709  C  CA  . PRO C 3 68  ? -11.959 22.549  42.285 1   108.25 ? 309 PRO P CA  1 
ATOM   3710  C  C   . PRO C 3 68  ? -11.328 22.858  43.653 1   107.87 ? 309 PRO P C   1 
ATOM   3711  O  O   . PRO C 3 68  ? -12.015 22.767  44.66  1   107.6  ? 309 PRO P O   1 
ATOM   3712  C  CB  . PRO C 3 68  ? -12.236 23.846  41.511 1   107.12 ? 309 PRO P CB  1 
ATOM   3713  C  CG  . PRO C 3 68  ? -13.611 24.258  41.987 1   108.61 ? 309 PRO P CG  1 
ATOM   3714  C  CD  . PRO C 3 68  ? -14.356 22.955  42.206 1   109.13 ? 309 PRO P CD  1 
ATOM   3715  N  N   . GLY C 3 69  ? -10.033 23.198  43.64  1   107.9  ? 310 GLY P N   1 
ATOM   3716  C  CA  . GLY C 3 69  ? -9.256  23.694  44.794 1   107.74 ? 310 GLY P CA  1 
ATOM   3717  C  C   . GLY C 3 69  ? -9.14   22.683  45.926 1   106.93 ? 310 GLY P C   1 
ATOM   3718  O  O   . GLY C 3 69  ? -9.008  23.128  47.084 1   106.18 ? 310 GLY P O   1 
ATOM   3719  N  N   . CYS C 3 70  ? -9.167  21.38   45.616 1   106.6  ? 311 CYS P N   1 
ATOM   3720  C  CA  . CYS C 3 70  ? -9.041  20.267  46.597 1   105.07 ? 311 CYS P CA  1 
ATOM   3721  C  C   . CYS C 3 70  ? -7.729  19.505  46.351 1   100.78 ? 311 CYS P C   1 
ATOM   3722  O  O   . CYS C 3 70  ? -7.738  18.259  46.426 1   102.1  ? 311 CYS P O   1 
ATOM   3723  C  CB  . CYS C 3 70  ? -10.256 19.348  46.534 1   105.24 ? 311 CYS P CB  1 
ATOM   3724  S  SG  . CYS C 3 70  ? -10.426 18.463  44.963 1   109.21 ? 311 CYS P SG  1 
ATOM   3725  N  N   . ALA C 3 71  ? -6.637  20.24   46.118 1   94.76  ? 312 ALA P N   1 
ATOM   3726  C  CA  . ALA C 3 71  ? -5.26   19.714  45.97  1   91.53  ? 312 ALA P CA  1 
ATOM   3727  C  C   . ALA C 3 71  ? -4.661  19.458  47.356 1   90.46  ? 312 ALA P C   1 
ATOM   3728  O  O   . ALA C 3 71  ? -4.087  18.371  47.557 1   91.08  ? 312 ALA P O   1 
ATOM   3729  C  CB  . ALA C 3 71  ? -4.414  20.686  45.183 1   91.28  ? 312 ALA P CB  1 
ATOM   3730  N  N   . GLU C 3 72  ? -4.785  20.438  48.26  1   92.06  ? 313 GLU P N   1 
ATOM   3731  C  CA  . GLU C 3 72  ? -4.269  20.405  49.659 1   92.35  ? 313 GLU P CA  1 
ATOM   3732  C  C   . GLU C 3 72  ? -4.799  19.165  50.383 1   89.56  ? 313 GLU P C   1 
ATOM   3733  O  O   . GLU C 3 72  ? -3.997  18.387  50.895 1   89.7   ? 313 GLU P O   1 
ATOM   3734  C  CB  . GLU C 3 72  ? -4.614  21.716  50.38  1   94.67  ? 313 GLU P CB  1 
ATOM   3735  C  CG  . GLU C 3 72  ? -4.133  21.802  51.819 1   94.17  ? 313 GLU P CG  1 
ATOM   3736  C  CD  . GLU C 3 72  ? -2.634  21.966  51.979 1   93.68  ? 313 GLU P CD  1 
ATOM   3737  O  OE1 . GLU C 3 72  ? -2.036  22.781  51.249 1   97.33  ? 313 GLU P OE1 1 
ATOM   3738  O  OE2 . GLU C 3 72  ? -2.061  21.261  52.832 1   91.68  ? 313 GLU P OE2 1 
ATOM   3739  N  N   . PRO C 3 73  ? -6.134  18.916  50.448 1   86.74  ? 314 PRO P N   1 
ATOM   3740  C  CA  . PRO C 3 73  ? -6.668  17.786  51.214 1   84.39  ? 314 PRO P CA  1 
ATOM   3741  C  C   . PRO C 3 73  ? -6.307  16.42   50.603 1   80.44  ? 314 PRO P C   1 
ATOM   3742  O  O   . PRO C 3 73  ? -6.069  15.492  51.36  1   78.19  ? 314 PRO P O   1 
ATOM   3743  C  CB  . PRO C 3 73  ? -8.194  18.003  51.2   1   85.42  ? 314 PRO P CB  1 
ATOM   3744  C  CG  . PRO C 3 73  ? -8.379  19.427  50.719 1   86.5   ? 314 PRO P CG  1 
ATOM   3745  C  CD  . PRO C 3 73  ? -7.216  19.659  49.781 1   86.53  ? 314 PRO P CD  1 
ATOM   3746  N  N   . TRP C 3 74  ? -6.272  16.333  49.267 1   75.83  ? 315 TRP P N   1 
ATOM   3747  C  CA  . TRP C 3 74  ? -5.881  15.118  48.5   1   74.42  ? 315 TRP P CA  1 
ATOM   3748  C  C   . TRP C 3 74  ? -4.477  14.656  48.919 1   75.7   ? 315 TRP P C   1 
ATOM   3749  O  O   . TRP C 3 74  ? -4.341  13.475  49.296 1   79.13  ? 315 TRP P O   1 
ATOM   3750  C  CB  . TRP C 3 74  ? -5.965  15.371  46.989 1   70.63  ? 315 TRP P CB  1 
ATOM   3751  C  CG  . TRP C 3 74  ? -5.515  14.201  46.173 1   67.33  ? 315 TRP P CG  1 
ATOM   3752  C  CD1 . TRP C 3 74  ? -4.299  14.027  45.582 1   66.63  ? 315 TRP P CD1 1 
ATOM   3753  C  CD2 . TRP C 3 74  ? -6.273  13.013  45.895 1   68.95  ? 315 TRP P CD2 1 
ATOM   3754  N  NE1 . TRP C 3 74  ? -4.25   12.818  44.944 1   68.1   ? 315 TRP P NE1 1 
ATOM   3755  C  CE2 . TRP C 3 74  ? -5.445  12.172  45.118 1   69.81  ? 315 TRP P CE2 1 
ATOM   3756  C  CE3 . TRP C 3 74  ? -7.564  12.578  46.222 1   68.29  ? 315 TRP P CE3 1 
ATOM   3757  C  CZ2 . TRP C 3 74  ? -5.875  10.925  44.659 1   70.23  ? 315 TRP P CZ2 1 
ATOM   3758  C  CZ3 . TRP C 3 74  ? -7.986  11.346  45.77  1   68.05  ? 315 TRP P CZ3 1 
ATOM   3759  C  CH2 . TRP C 3 74  ? -7.151  10.532  45.001 1   69.29  ? 315 TRP P CH2 1 
ATOM   3760  N  N   . ASN C 3 75  ? -3.491  15.56   48.888 1   74.89  ? 316 ASN P N   1 
ATOM   3761  C  CA  . ASN C 3 75  ? -2.064  15.282  49.22  1   76.73  ? 316 ASN P CA  1 
ATOM   3762  C  C   . ASN C 3 75  ? -1.915  14.969  50.718 1   79.4   ? 316 ASN P C   1 
ATOM   3763  O  O   . ASN C 3 75  ? -0.947  14.26   51.07  1   78.43  ? 316 ASN P O   1 
ATOM   3764  C  CB  . ASN C 3 75  ? -1.145  16.441  48.816 1   76.72  ? 316 ASN P CB  1 
ATOM   3765  C  CG  . ASN C 3 75  ? -1.186  16.762  47.334 1   76.24  ? 316 ASN P CG  1 
ATOM   3766  O  OD1 . ASN C 3 75  ? -1.457  15.892  46.508 1   74.88  ? 316 ASN P OD1 1 
ATOM   3767  N  ND2 . ASN C 3 75  ? -0.912  18.009  46.983 1   76.13  ? 316 ASN P ND2 1 
ATOM   3768  N  N   . HIS C 3 76  ? -2.824  15.483  51.561 1   83.6   ? 317 HIS P N   1 
ATOM   3769  C  CA  . HIS C 3 76  ? -2.913  15.194  53.023 1   85.48  ? 317 HIS P CA  1 
ATOM   3770  C  C   . HIS C 3 76  ? -3.419  13.763  53.265 1   82.79  ? 317 HIS P C   1 
ATOM   3771  O  O   . HIS C 3 76  ? -3.185  13.242  54.379 1   76.77  ? 317 HIS P O   1 
ATOM   3772  C  CB  . HIS C 3 76  ? -3.776  16.253  53.746 1   87.45  ? 317 HIS P CB  1 
ATOM   3773  C  CG  . HIS C 3 76  ? -3.008  17.453  54.194 1   87.42  ? 317 HIS P CG  1 
ATOM   3774  N  ND1 . HIS C 3 76  ? -3.481  18.34   55.143 1   85.61  ? 317 HIS P ND1 1 
ATOM   3775  C  CD2 . HIS C 3 76  ? -1.779  17.888  53.853 1   88.36  ? 317 HIS P CD2 1 
ATOM   3776  C  CE1 . HIS C 3 76  ? -2.584  19.286  55.343 1   85.37  ? 317 HIS P CE1 1 
ATOM   3777  N  NE2 . HIS C 3 76  ? -1.53   19.031  54.563 1   86.94  ? 317 HIS P NE2 1 
ATOM   3778  N  N   . GLY C 3 77  ? -4.079  13.158  52.27  1   81.34  ? 318 GLY P N   1 
ATOM   3779  C  CA  . GLY C 3 77  ? -4.599  11.779  52.318 1   80.68  ? 318 GLY P CA  1 
ATOM   3780  C  C   . GLY C 3 77  ? -6.032  11.733  52.818 1   79.71  ? 318 GLY P C   1 
ATOM   3781  O  O   . GLY C 3 77  ? -6.497  10.625  53.146 1   81.26  ? 318 GLY P O   1 
ATOM   3782  N  N   . LYS C 3 78  ? -6.71   12.885  52.881 1   78.91  ? 319 LYS P N   1 
ATOM   3783  C  CA  . LYS C 3 78  ? -8.139  12.983  53.278 1   79.03  ? 319 LYS P CA  1 
ATOM   3784  C  C   . LYS C 3 78  ? -8.977  12.259  52.22  1   77.04  ? 319 LYS P C   1 
ATOM   3785  O  O   . LYS C 3 78  ? -8.643  12.371  51.025 1   80.03  ? 319 LYS P O   1 
ATOM   3786  C  CB  . LYS C 3 78  ? -8.579  14.442  53.453 1   80.34  ? 319 LYS P CB  1 
ATOM   3787  C  CG  . LYS C 3 78  ? -8.015  15.141  54.686 1   81.33  ? 319 LYS P CG  1 
ATOM   3788  C  CD  . LYS C 3 78  ? -8.683  16.465  55.002 1   80.61  ? 319 LYS P CD  1 
ATOM   3789  C  CE  . LYS C 3 78  ? -7.941  17.283  56.03  0   82.38  ? 319 LYS P CE  1 
ATOM   3790  N  NZ  . LYS C 3 78  ? -8.418  18.685  56.075 0   82.36  ? 319 LYS P NZ  1 
ATOM   3791  N  N   . THR C 3 79  ? -9.997  11.521  52.667 1   75.42  ? 320 THR P N   1 
ATOM   3792  C  CA  . THR C 3 79  ? -10.92  10.708  51.832 1   72.66  ? 320 THR P CA  1 
ATOM   3793  C  C   . THR C 3 79  ? -12.044 11.599  51.297 1   70.22  ? 320 THR P C   1 
ATOM   3794  O  O   . THR C 3 79  ? -12.561 12.427  52.068 1   66.11  ? 320 THR P O   1 
ATOM   3795  C  CB  . THR C 3 79  ? -11.471 9.514   52.622 1   70.97  ? 320 THR P CB  1 
ATOM   3796  O  OG1 . THR C 3 79  ? -10.355 8.761   53.099 1   69.25  ? 320 THR P OG1 1 
ATOM   3797  C  CG2 . THR C 3 79  ? -12.374 8.622   51.801 1   71.44  ? 320 THR P CG2 1 
ATOM   3798  N  N   . PHE C 3 80  ? -12.401 11.404  50.025 1   73.48  ? 321 PHE P N   1 
ATOM   3799  C  CA  . PHE C 3 80  ? -13.452 12.154  49.293 1   77.07  ? 321 PHE P CA  1 
ATOM   3800  C  C   . PHE C 3 80  ? -14.648 11.225  49.073 1   79.12  ? 321 PHE P C   1 
ATOM   3801  O  O   . PHE C 3 80  ? -14.444 10.08   48.621 1   81.18  ? 321 PHE P O   1 
ATOM   3802  C  CB  . PHE C 3 80  ? -12.906 12.703  47.97  1   78.45  ? 321 PHE P CB  1 
ATOM   3803  C  CG  . PHE C 3 80  ? -11.938 13.85   48.123 1   79.52  ? 321 PHE P CG  1 
ATOM   3804  C  CD1 . PHE C 3 80  ? -10.679 13.653  48.674 1   80.51  ? 321 PHE P CD1 1 
ATOM   3805  C  CD2 . PHE C 3 80  ? -12.287 15.129  47.716 1   80.95  ? 321 PHE P CD2 1 
ATOM   3806  C  CE1 . PHE C 3 80  ? -9.796  14.713  48.823 1   82.77  ? 321 PHE P CE1 1 
ATOM   3807  C  CE2 . PHE C 3 80  ? -11.406 16.188  47.87  1   81.17  ? 321 PHE P CE2 1 
ATOM   3808  C  CZ  . PHE C 3 80  ? -10.161 15.979  48.421 1   83.88  ? 321 PHE P CZ  1 
ATOM   3809  N  N   . THR C 3 81  ? -15.845 11.708  49.414 1   81.98  ? 322 THR P N   1 
ATOM   3810  C  CA  . THR C 3 81  ? -17.153 11.048  49.169 1   84.49  ? 322 THR P CA  1 
ATOM   3811  C  C   . THR C 3 81  ? -17.956 11.935  48.214 1   88.09  ? 322 THR P C   1 
ATOM   3812  O  O   . THR C 3 81  ? -17.967 13.16   48.431 1   86.75  ? 322 THR P O   1 
ATOM   3813  C  CB  . THR C 3 81  ? -17.896 10.811  50.489 1   83.68  ? 322 THR P CB  1 
ATOM   3814  O  OG1 . THR C 3 81  ? -17.012 10.154  51.398 1   83.44  ? 322 THR P OG1 1 
ATOM   3815  C  CG2 . THR C 3 81  ? -19.161 9.999   50.324 1   84.97  ? 322 THR P CG2 1 
ATOM   3816  N  N   . CYS C 3 82  ? -18.571 11.333  47.192 1   96.13  ? 323 CYS P N   1 
ATOM   3817  C  CA  . CYS C 3 82  ? -19.469 11.998  46.21  1   104.82 ? 323 CYS P CA  1 
ATOM   3818  C  C   . CYS C 3 82  ? -20.759 11.178  46.075 1   108.86 ? 323 CYS P C   1 
ATOM   3819  O  O   . CYS C 3 82  ? -20.706 10.102  45.441 1   105.57 ? 323 CYS P O   1 
ATOM   3820  C  CB  . CYS C 3 82  ? -18.784 12.152  44.857 1   109.51 ? 323 CYS P CB  1 
ATOM   3821  S  SG  . CYS C 3 82  ? -19.878 12.785  43.558 1   115.35 ? 323 CYS P SG  1 
ATOM   3822  N  N   . THR C 3 83  ? -21.858 11.668  46.664 1   113.17 ? 324 THR P N   1 
ATOM   3823  C  CA  . THR C 3 83  ? -23.216 11.062  46.602 1   114.85 ? 324 THR P CA  1 
ATOM   3824  C  C   . THR C 3 83  ? -24.062 11.834  45.584 1   120.59 ? 324 THR P C   1 
ATOM   3825  O  O   . THR C 3 83  ? -23.979 13.079  45.579 1   120.17 ? 324 THR P O   1 
ATOM   3826  C  CB  . THR C 3 83  ? -23.878 11.034  47.985 1   111.88 ? 324 THR P CB  1 
ATOM   3827  O  OG1 . THR C 3 83  ? -23.776 12.343  48.547 1   112.95 ? 324 THR P OG1 1 
ATOM   3828  C  CG2 . THR C 3 83  ? -23.247 10.027  48.922 1   109.49 ? 324 THR P CG2 1 
ATOM   3829  N  N   . ALA C 3 84  ? -24.84  11.112  44.768 1   130.46 ? 325 ALA P N   1 
ATOM   3830  C  CA  . ALA C 3 84  ? -25.635 11.642  43.634 1   141.14 ? 325 ALA P CA  1 
ATOM   3831  C  C   . ALA C 3 84  ? -27.113 11.265  43.799 1   148.88 ? 325 ALA P C   1 
ATOM   3832  O  O   . ALA C 3 84  ? -27.421 10.053  43.771 1   147.61 ? 325 ALA P O   1 
ATOM   3833  C  CB  . ALA C 3 84  ? -25.084 11.103  42.337 1   144.45 ? 325 ALA P CB  1 
ATOM   3834  N  N   . ALA C 3 85  ? -27.984 12.271  43.958 1   156.55 ? 326 ALA P N   1 
ATOM   3835  C  CA  . ALA C 3 85  ? -29.461 12.144  43.951 1   158.81 ? 326 ALA P CA  1 
ATOM   3836  C  C   . ALA C 3 85  ? -29.969 12.378  42.522 1   160.9  ? 326 ALA P C   1 
ATOM   3837  O  O   . ALA C 3 85  ? -29.863 13.527  42.042 1   157.31 ? 326 ALA P O   1 
ATOM   3838  C  CB  . ALA C 3 85  ? -30.077 13.118  44.929 1   157.1  ? 326 ALA P CB  1 
ATOM   3839  N  N   . TYR C 3 86  ? -30.481 11.324  41.873 1   163.66 ? 327 TYR P N   1 
ATOM   3840  C  CA  . TYR C 3 86  ? -30.955 11.324  40.46  1   161.39 ? 327 TYR P CA  1 
ATOM   3841  C  C   . TYR C 3 86  ? -32.399 10.823  40.412 1   158.92 ? 327 TYR P C   1 
ATOM   3842  O  O   . TYR C 3 86  ? -32.805 10.026  41.257 1   153.11 ? 327 TYR P O   1 
ATOM   3843  C  CB  . TYR C 3 86  ? -29.997 10.518  39.574 1   160.64 ? 327 TYR P CB  1 
ATOM   3844  C  CG  . TYR C 3 86  ? -29.805 9.067   39.945 1   159.72 ? 327 TYR P CG  1 
ATOM   3845  C  CD1 . TYR C 3 86  ? -28.856 8.683   40.882 1   159.3  ? 327 TYR P CD1 1 
ATOM   3846  C  CD2 . TYR C 3 86  ? -30.546 8.067   39.332 1   158.23 ? 327 TYR P CD2 1 
ATOM   3847  C  CE1 . TYR C 3 86  ? -28.665 7.35    41.217 1   158.03 ? 327 TYR P CE1 1 
ATOM   3848  C  CE2 . TYR C 3 86  ? -30.366 6.73    39.654 1   155.56 ? 327 TYR P CE2 1 
ATOM   3849  C  CZ  . TYR C 3 86  ? -29.422 6.369   40.599 1   154.93 ? 327 TYR P CZ  1 
ATOM   3850  O  OH  . TYR C 3 86  ? -29.245 5.053   40.916 1   153.95 ? 327 TYR P OH  1 
ATOM   3851  N  N   . PRO C 3 87  ? -33.217 11.271  39.427 1   158.52 ? 328 PRO P N   1 
ATOM   3852  C  CA  . PRO C 3 87  ? -34.666 11.042  39.46  1   154.2  ? 328 PRO P CA  1 
ATOM   3853  C  C   . PRO C 3 87  ? -35.16  9.628   39.098 1   148.13 ? 328 PRO P C   1 
ATOM   3854  O  O   . PRO C 3 87  ? -36.331 9.372   39.32  1   148.14 ? 328 PRO P O   1 
ATOM   3855  C  CB  . PRO C 3 87  ? -35.178 12.051  38.419 1   155.15 ? 328 PRO P CB  1 
ATOM   3856  C  CG  . PRO C 3 87  ? -34.062 12.124  37.402 1   154.84 ? 328 PRO P CG  1 
ATOM   3857  C  CD  . PRO C 3 87  ? -32.797 12.018  38.227 1   155.63 ? 328 PRO P CD  1 
ATOM   3858  N  N   . GLU C 3 88  ? -34.292 8.761   38.559 1   138.86 ? 329 GLU P N   1 
ATOM   3859  C  CA  . GLU C 3 88  ? -34.64  7.374   38.136 1   132.56 ? 329 GLU P CA  1 
ATOM   3860  C  C   . GLU C 3 88  ? -34.904 6.509   39.378 1   131.62 ? 329 GLU P C   1 
ATOM   3861  O  O   . GLU C 3 88  ? -35.957 5.841   39.41  1   132.27 ? 329 GLU P O   1 
ATOM   3862  C  CB  . GLU C 3 88  ? -33.532 6.78    37.261 1   128.59 ? 329 GLU P CB  1 
ATOM   3863  C  CG  . GLU C 3 88  ? -33.955 5.53    36.505 1   125.06 ? 329 GLU P CG  1 
ATOM   3864  C  CD  . GLU C 3 88  ? -32.919 4.971   35.54  1   118.62 ? 329 GLU P CD  1 
ATOM   3865  O  OE1 . GLU C 3 88  ? -32.296 5.768   34.813 1   109.95 ? 329 GLU P OE1 1 
ATOM   3866  O  OE2 . GLU C 3 88  ? -32.739 3.736   35.518 1   112.56 ? 329 GLU P OE2 1 
ATOM   3867  N  N   . SER C 3 89  ? -33.983 6.521   40.349 1   129.52 ? 330 SER P N   1 
ATOM   3868  C  CA  . SER C 3 89  ? -34.089 5.813   41.656 1   126.75 ? 330 SER P CA  1 
ATOM   3869  C  C   . SER C 3 89  ? -34.541 6.793   42.748 1   130.88 ? 330 SER P C   1 
ATOM   3870  O  O   . SER C 3 89  ? -34.617 8.008   42.463 1   128.24 ? 330 SER P O   1 
ATOM   3871  C  CB  . SER C 3 89  ? -32.785 5.148   42.016 1   122.29 ? 330 SER P CB  1 
ATOM   3872  O  OG  . SER C 3 89  ? -32.945 4.292   43.137 1   115.8  ? 330 SER P OG  1 
ATOM   3873  N  N   . LYS C 3 90  ? -34.828 6.276   43.95  1   135.51 ? 331 LYS P N   1 
ATOM   3874  C  CA  . LYS C 3 90  ? -35.359 7.046   45.111 1   136.37 ? 331 LYS P CA  1 
ATOM   3875  C  C   . LYS C 3 90  ? -34.203 7.496   46.016 1   139.51 ? 331 LYS P C   1 
ATOM   3876  O  O   . LYS C 3 90  ? -34.169 8.698   46.358 1   136.04 ? 331 LYS P O   1 
ATOM   3877  C  CB  . LYS C 3 90  ? -36.379 6.208   45.891 1   134.53 ? 331 LYS P CB  1 
ATOM   3878  C  CG  . LYS C 3 90  ? -37.676 5.91    45.15  1   131.06 ? 331 LYS P CG  1 
ATOM   3879  C  CD  . LYS C 3 90  ? -38.685 5.148   45.974 0   137    ? 331 LYS P CD  1 
ATOM   3880  C  CE  . LYS C 3 90  ? -39.984 4.902   45.238 0   136.82 ? 331 LYS P CE  1 
ATOM   3881  N  NZ  . LYS C 3 90  ? -40.935 4.111   46.054 0   136.72 ? 331 LYS P NZ  1 
ATOM   3882  N  N   . THR C 3 91  ? -33.309 6.57    46.393 1   142.41 ? 332 THR P N   1 
ATOM   3883  C  CA  . THR C 3 91  ? -32.138 6.809   47.288 1   141.9  ? 332 THR P CA  1 
ATOM   3884  C  C   . THR C 3 91  ? -30.872 7.014   46.453 1   147.52 ? 332 THR P C   1 
ATOM   3885  O  O   . THR C 3 91  ? -30.798 6.53    45.323 1   149.33 ? 332 THR P O   1 
ATOM   3886  C  CB  . THR C 3 91  ? -31.963 5.663   48.295 1   134.49 ? 332 THR P CB  1 
ATOM   3887  O  OG1 . THR C 3 91  ? -31.893 4.432   47.574 1   130.04 ? 332 THR P OG1 1 
ATOM   3888  C  CG2 . THR C 3 91  ? -33.081 5.598   49.312 1   130.12 ? 332 THR P CG2 1 
ATOM   3889  N  N   . PRO C 3 92  ? -29.83  7.717   46.971 1   150.67 ? 333 PRO P N   1 
ATOM   3890  C  CA  . PRO C 3 92  ? -28.618 7.995   46.196 1   147.52 ? 333 PRO P CA  1 
ATOM   3891  C  C   . PRO C 3 92  ? -27.651 6.802   46.104 1   145.18 ? 333 PRO P C   1 
ATOM   3892  O  O   . PRO C 3 92  ? -27.916 5.776   46.71  1   141.96 ? 333 PRO P O   1 
ATOM   3893  C  CB  . PRO C 3 92  ? -27.927 9.146   46.956 1   148.26 ? 333 PRO P CB  1 
ATOM   3894  C  CG  . PRO C 3 92  ? -28.842 9.488   48.123 1   148.27 ? 333 PRO P CG  1 
ATOM   3895  C  CD  . PRO C 3 92  ? -29.739 8.285   48.326 1   150.23 ? 333 PRO P CD  1 
ATOM   3896  N  N   . LEU C 3 93  ? -26.558 6.98    45.35  1   145.05 ? 334 LEU P N   1 
ATOM   3897  C  CA  . LEU C 3 93  ? -25.38  6.066   45.293 1   141.53 ? 334 LEU P CA  1 
ATOM   3898  C  C   . LEU C 3 93  ? -24.195 6.723   46.017 1   136.99 ? 334 LEU P C   1 
ATOM   3899  O  O   . LEU C 3 93  ? -24.264 7.94    46.283 1   135.12 ? 334 LEU P O   1 
ATOM   3900  C  CB  . LEU C 3 93  ? -25.039 5.764   43.829 1   138.93 ? 334 LEU P CB  1 
ATOM   3901  C  CG  . LEU C 3 93  ? -26.014 4.84    43.099 1   138.54 ? 334 LEU P CG  1 
ATOM   3902  C  CD1 . LEU C 3 93  ? -25.827 4.935   41.591 1   137.81 ? 334 LEU P CD1 1 
ATOM   3903  C  CD2 . LEU C 3 93  ? -25.858 3.399   43.564 1   137.07 ? 334 LEU P CD2 1 
ATOM   3904  N  N   . THR C 3 94  ? -23.154 5.939   46.325 1   130.76 ? 335 THR P N   1 
ATOM   3905  C  CA  . THR C 3 94  ? -21.947 6.364   47.09  1   127.43 ? 335 THR P CA  1 
ATOM   3906  C  C   . THR C 3 94  ? -20.682 5.836   46.399 1   125.31 ? 335 THR P C   1 
ATOM   3907  O  O   . THR C 3 94  ? -20.708 4.686   45.909 1   126.36 ? 335 THR P O   1 
ATOM   3908  C  CB  . THR C 3 94  ? -22.043 5.901   48.551 1   125.79 ? 335 THR P CB  1 
ATOM   3909  O  OG1 . THR C 3 94  ? -23.19  6.527   49.126 1   121.49 ? 335 THR P OG1 1 
ATOM   3910  C  CG2 . THR C 3 94  ? -20.824 6.239   49.384 1   125.2  ? 335 THR P CG2 1 
ATOM   3911  N  N   . ALA C 3 95  ? -19.621 6.652   46.383 1   122.25 ? 336 ALA P N   1 
ATOM   3912  C  CA  . ALA C 3 95  ? -18.278 6.324   45.846 1   119.21 ? 336 ALA P CA  1 
ATOM   3913  C  C   . ALA C 3 95  ? -17.197 6.977   46.72  1   112.84 ? 336 ALA P C   1 
ATOM   3914  O  O   . ALA C 3 95  ? -17.315 8.189   47     1   107.76 ? 336 ALA P O   1 
ATOM   3915  C  CB  . ALA C 3 95  ? -18.173 6.778   44.41  1   119.52 ? 336 ALA P CB  1 
ATOM   3916  N  N   . THR C 3 96  ? -16.184 6.198   47.119 1   107.95 ? 337 THR P N   1 
ATOM   3917  C  CA  . THR C 3 96  ? -15.058 6.605   48.006 1   105.79 ? 337 THR P CA  1 
ATOM   3918  C  C   . THR C 3 96  ? -13.758 6.642   47.189 1   102.16 ? 337 THR P C   1 
ATOM   3919  O  O   . THR C 3 96  ? -13.531 5.695   46.405 1   103.65 ? 337 THR P O   1 
ATOM   3920  C  CB  . THR C 3 96  ? -14.973 5.658   49.211 1   104.87 ? 337 THR P CB  1 
ATOM   3921  O  OG1 . THR C 3 96  ? -16.128 5.911   50.01  1   104.41 ? 337 THR P OG1 1 
ATOM   3922  C  CG2 . THR C 3 96  ? -13.726 5.83    50.053 1   104.53 ? 337 THR P CG2 1 
ATOM   3923  N  N   . LEU C 3 97  ? -12.942 7.69    47.372 1   94.4   ? 338 LEU P N   1 
ATOM   3924  C  CA  . LEU C 3 97  ? -11.587 7.819   46.765 1   88.03  ? 338 LEU P CA  1 
ATOM   3925  C  C   . LEU C 3 97  ? -10.704 8.712   47.646 1   82.41  ? 338 LEU P C   1 
ATOM   3926  O  O   . LEU C 3 97  ? -11.165 9.803   48.027 1   75.85  ? 338 LEU P O   1 
ATOM   3927  C  CB  . LEU C 3 97  ? -11.713 8.39    45.346 1   86.7   ? 338 LEU P CB  1 
ATOM   3928  C  CG  . LEU C 3 97  ? -10.418 8.49    44.534 1   84.55  ? 338 LEU P CG  1 
ATOM   3929  C  CD1 . LEU C 3 97  ? -9.748  7.134   44.368 1   83.42  ? 338 LEU P CD1 1 
ATOM   3930  C  CD2 . LEU C 3 97  ? -10.684 9.107   43.169 1   84.08  ? 338 LEU P CD2 1 
ATOM   3931  N  N   . SER C 3 98  ? -9.488  8.243   47.955 1   79.1   ? 339 SER P N   1 
ATOM   3932  C  CA  . SER C 3 98  ? -8.396  9.003   48.62  1   75.41  ? 339 SER P CA  1 
ATOM   3933  C  C   . SER C 3 98  ? -7.064  8.704   47.916 1   75.39  ? 339 SER P C   1 
ATOM   3934  O  O   . SER C 3 98  ? -6.986  7.677   47.211 1   69.41  ? 339 SER P O   1 
ATOM   3935  C  CB  . SER C 3 98  ? -8.328  8.679   50.092 1   71.99  ? 339 SER P CB  1 
ATOM   3936  O  OG  . SER C 3 98  ? -7.536  7.526   50.334 1   71.67  ? 339 SER P OG  1 
ATOM   3937  N  N   . LYS C 3 99  ? -6.061  9.569   48.111 1   78.59  ? 340 LYS P N   1 
ATOM   3938  C  CA  . LYS C 3 99  ? -4.662  9.361   47.641 1   78.58  ? 340 LYS P CA  1 
ATOM   3939  C  C   . LYS C 3 99  ? -4.172  7.998   48.15  1   77.86  ? 340 LYS P C   1 
ATOM   3940  O  O   . LYS C 3 99  ? -4.395  7.701   49.34  1   74.74  ? 340 LYS P O   1 
ATOM   3941  C  CB  . LYS C 3 99  ? -3.737  10.486  48.121 1   80.55  ? 340 LYS P CB  1 
ATOM   3942  C  CG  . LYS C 3 99  ? -2.377  10.545  47.432 1   83.53  ? 340 LYS P CG  1 
ATOM   3943  C  CD  . LYS C 3 99  ? -1.201  10.834  48.351 1   83.04  ? 340 LYS P CD  1 
ATOM   3944  C  CE  . LYS C 3 99  ? 0.132   10.677  47.645 1   83.55  ? 340 LYS P CE  1 
ATOM   3945  N  NZ  . LYS C 3 99  ? 1.267   10.621  48.596 1   83.39  ? 340 LYS P NZ  1 
ATOM   3946  N  N   . SER C 3 100 ? -3.541  7.211   47.27  1   77.22  ? 341 SER P N   1 
ATOM   3947  C  CA  . SER C 3 100 ? -3.161  5.79    47.493 1   78.96  ? 341 SER P CA  1 
ATOM   3948  C  C   . SER C 3 100 ? -2.051  5.689   48.548 1   77.91  ? 341 SER P C   1 
ATOM   3949  O  O   . SER C 3 100 ? -1.184  6.587   48.591 1   74.72  ? 341 SER P O   1 
ATOM   3950  C  CB  . SER C 3 100 ? -2.742  5.129   46.199 1   79.6   ? 341 SER P CB  1 
ATOM   3951  O  OG  . SER C 3 100 ? -3.675  5.401   45.162 1   79.67  ? 341 SER P OG  1 
ATOM   3952  N  N   . GLY C 3 101 ? -2.094  4.636   49.37  1   79.84  ? 342 GLY P N   1 
ATOM   3953  C  CA  . GLY C 3 101 ? -1.024  4.267   50.318 1   84.11  ? 342 GLY P CA  1 
ATOM   3954  C  C   . GLY C 3 101 ? -0.037  3.3     49.682 1   85.09  ? 342 GLY P C   1 
ATOM   3955  O  O   . GLY C 3 101 ? -0.184  3.028   48.469 1   86.34  ? 342 GLY P O   1 
ATOM   3956  N  N   . ASN C 3 102 ? 0.923   2.795   50.467 1   84.08  ? 343 ASN P N   1 
ATOM   3957  C  CA  . ASN C 3 102 ? 1.961   1.816   50.037 1   83.44  ? 343 ASN P CA  1 
ATOM   3958  C  C   . ASN C 3 102 ? 2.56    2.276   48.698 1   81.03  ? 343 ASN P C   1 
ATOM   3959  O  O   . ASN C 3 102 ? 2.525   1.486   47.729 1   78.59  ? 343 ASN P O   1 
ATOM   3960  C  CB  . ASN C 3 102 ? 1.394   0.391   49.981 1   81.65  ? 343 ASN P CB  1 
ATOM   3961  C  CG  . ASN C 3 102 ? 0.859   -0.124  51.279 0   84.38  ? 343 ASN P CG  1 
ATOM   3962  O  OD1 . ASN C 3 102 ? 1       0.526   52.313 0   84.32  ? 343 ASN P OD1 1 
ATOM   3963  N  ND2 . ASN C 3 102 ? 0.231   -1.289  51.255 0   84.32  ? 343 ASN P ND2 1 
ATOM   3964  N  N   . THR C 3 103 ? 3.065   3.516   48.654 1   74.24  ? 344 THR P N   1 
ATOM   3965  C  CA  . THR C 3 103 ? 3.69    4.156   47.464 1   72.81  ? 344 THR P CA  1 
ATOM   3966  C  C   . THR C 3 103 ? 5.145   3.693   47.329 1   73.28  ? 344 THR P C   1 
ATOM   3967  O  O   . THR C 3 103 ? 5.787   3.468   48.37  1   79.57  ? 344 THR P O   1 
ATOM   3968  C  CB  . THR C 3 103 ? 3.657   5.69    47.534 1   72.13  ? 344 THR P CB  1 
ATOM   3969  O  OG1 . THR C 3 103 ? 4.519   6.123   48.588 1   69.08  ? 344 THR P OG1 1 
ATOM   3970  C  CG2 . THR C 3 103 ? 2.267   6.25    47.74  1   72.46  ? 344 THR P CG2 1 
ATOM   3971  N  N   . PHE C 3 104 ? 5.641   3.58    46.093 1   72.95  ? 345 PHE P N   1 
ATOM   3972  C  CA  . PHE C 3 104 ? 7.064   3.307   45.749 1   73.59  ? 345 PHE P CA  1 
ATOM   3973  C  C   . PHE C 3 104 ? 7.488   4.289   44.651 1   70.62  ? 345 PHE P C   1 
ATOM   3974  O  O   . PHE C 3 104 ? 6.716   4.479   43.69  1   67.34  ? 345 PHE P O   1 
ATOM   3975  C  CB  . PHE C 3 104 ? 7.263   1.85    45.321 1   76.94  ? 345 PHE P CB  1 
ATOM   3976  C  CG  . PHE C 3 104 ? 6.825   0.827   46.34  1   81.08  ? 345 PHE P CG  1 
ATOM   3977  C  CD1 . PHE C 3 104 ? 7.417   0.776   47.594 1   83.79  ? 345 PHE P CD1 1 
ATOM   3978  C  CD2 . PHE C 3 104 ? 5.823   -0.089  46.05  1   82.71  ? 345 PHE P CD2 1 
ATOM   3979  C  CE1 . PHE C 3 104 ? 7.008   -0.159  48.536 1   85.21  ? 345 PHE P CE1 1 
ATOM   3980  C  CE2 . PHE C 3 104 ? 5.414   -1.021  46.993 1   83.96  ? 345 PHE P CE2 1 
ATOM   3981  C  CZ  . PHE C 3 104 ? 6.008   -1.057  48.234 1   84.29  ? 345 PHE P CZ  1 
ATOM   3982  N  N   . ARG C 3 105 ? 8.655   4.922   44.807 1   69.5   ? 346 ARG P N   1 
ATOM   3983  C  CA  . ARG C 3 105 ? 9.186   5.915   43.835 1   70.16  ? 346 ARG P CA  1 
ATOM   3984  C  C   . ARG C 3 105 ? 9.66    5.168   42.59  1   63.67  ? 346 ARG P C   1 
ATOM   3985  O  O   . ARG C 3 105 ? 10.19   4.064   42.705 1   61.32  ? 346 ARG P O   1 
ATOM   3986  C  CB  . ARG C 3 105 ? 10.285  6.781   44.466 1   76.56  ? 346 ARG P CB  1 
ATOM   3987  C  CG  . ARG C 3 105 ? 11.607  6.074   44.744 1   82.87  ? 346 ARG P CG  1 
ATOM   3988  C  CD  . ARG C 3 105 ? 12.638  6.969   45.416 1   86.85  ? 346 ARG P CD  1 
ATOM   3989  N  NE  . ARG C 3 105 ? 12.078  7.831   46.458 1   90.78  ? 346 ARG P NE  1 
ATOM   3990  C  CZ  . ARG C 3 105 ? 11.674  7.436   47.67  1   88.7   ? 346 ARG P CZ  1 
ATOM   3991  N  NH1 . ARG C 3 105 ? 11.756  6.166   48.041 1   87.13  ? 346 ARG P NH1 1 
ATOM   3992  N  NH2 . ARG C 3 105 ? 11.182  8.328   48.516 1   88.45  ? 346 ARG P NH2 1 
ATOM   3993  N  N   . PRO C 3 106 ? 9.472   5.726   41.371 1   58.68  ? 347 PRO P N   1 
ATOM   3994  C  CA  . PRO C 3 106 ? 9.912   5.068   40.146 1   59.11  ? 347 PRO P CA  1 
ATOM   3995  C  C   . PRO C 3 106 ? 11.442  5.023   40.06  1   58.28  ? 347 PRO P C   1 
ATOM   3996  O  O   . PRO C 3 106 ? 12.086  5.957   40.497 1   57.66  ? 347 PRO P O   1 
ATOM   3997  C  CB  . PRO C 3 106 ? 9.313   5.933   39.028 1   60.25  ? 347 PRO P CB  1 
ATOM   3998  C  CG  . PRO C 3 106 ? 9.198   7.298   39.651 1   59.07  ? 347 PRO P CG  1 
ATOM   3999  C  CD  . PRO C 3 106 ? 8.827   7.015   41.089 1   59.21  ? 347 PRO P CD  1 
ATOM   4000  N  N   . GLU C 3 107 ? 11.967  3.909   39.551 1   58.15  ? 348 GLU P N   1 
ATOM   4001  C  CA  . GLU C 3 107 ? 13.387  3.74    39.158 1   58.27  ? 348 GLU P CA  1 
ATOM   4002  C  C   . GLU C 3 107 ? 13.457  4.082   37.666 1   53.92  ? 348 GLU P C   1 
ATOM   4003  O  O   . GLU C 3 107 ? 12.782  3.386   36.878 1   50.78  ? 348 GLU P O   1 
ATOM   4004  C  CB  . GLU C 3 107 ? 13.855  2.321   39.5   1   63.98  ? 348 GLU P CB  1 
ATOM   4005  C  CG  . GLU C 3 107 ? 15.307  2.242   39.951 1   72.49  ? 348 GLU P CG  1 
ATOM   4006  C  CD  . GLU C 3 107 ? 15.619  2.84    41.319 1   76.56  ? 348 GLU P CD  1 
ATOM   4007  O  OE1 . GLU C 3 107 ? 14.809  2.648   42.258 1   72.66  ? 348 GLU P OE1 1 
ATOM   4008  O  OE2 . GLU C 3 107 ? 16.68   3.498   41.443 1   77.79  ? 348 GLU P OE2 1 
ATOM   4009  N  N   . VAL C 3 108 ? 14.17   5.157   37.307 1   49.94  ? 349 VAL P N   1 
ATOM   4010  C  CA  . VAL C 3 108 ? 14.238  5.683   35.91  1   48.06  ? 349 VAL P CA  1 
ATOM   4011  C  C   . VAL C 3 108 ? 15.597  5.317   35.311 1   47.39  ? 349 VAL P C   1 
ATOM   4012  O  O   . VAL C 3 108 ? 16.62   5.434   36.014 1   47.9   ? 349 VAL P O   1 
ATOM   4013  C  CB  . VAL C 3 108 ? 13.979  7.197   35.84  1   47.66  ? 349 VAL P CB  1 
ATOM   4014  C  CG1 . VAL C 3 108 ? 14.042  7.723   34.412 1   47.35  ? 349 VAL P CG1 1 
ATOM   4015  C  CG2 . VAL C 3 108 ? 12.644  7.554   36.47  1   48.7   ? 349 VAL P CG2 1 
ATOM   4016  N  N   . HIS C 3 109 ? 15.582  4.884   34.051 1   45.6   ? 350 HIS P N   1 
ATOM   4017  C  CA  . HIS C 3 109 ? 16.774  4.486   33.263 1   45.75  ? 350 HIS P CA  1 
ATOM   4018  C  C   . HIS C 3 109 ? 16.608  5.012   31.838 1   46.04  ? 350 HIS P C   1 
ATOM   4019  O  O   . HIS C 3 109 ? 15.565  4.707   31.212 1   46.2   ? 350 HIS P O   1 
ATOM   4020  C  CB  . HIS C 3 109 ? 16.961  2.965   33.275 1   45.95  ? 350 HIS P CB  1 
ATOM   4021  C  CG  . HIS C 3 109 ? 16.791  2.351   34.62  1   46.95  ? 350 HIS P CG  1 
ATOM   4022  N  ND1 . HIS C 3 109 ? 17.764  2.433   35.593 1   49.38  ? 350 HIS P ND1 1 
ATOM   4023  C  CD2 . HIS C 3 109 ? 15.766  1.659   35.16  1   48.79  ? 350 HIS P CD2 1 
ATOM   4024  C  CE1 . HIS C 3 109 ? 17.352  1.806   36.677 1   49.77  ? 350 HIS P CE1 1 
ATOM   4025  N  NE2 . HIS C 3 109 ? 16.128  1.319   36.435 1   50.3   ? 350 HIS P NE2 1 
ATOM   4026  N  N   . LEU C 3 110 ? 17.579  5.797   31.37  1   44.75  ? 351 LEU P N   1 
ATOM   4027  C  CA  . LEU C 3 110 ? 17.65   6.261   29.967 1   44.63  ? 351 LEU P CA  1 
ATOM   4028  C  C   . LEU C 3 110 ? 18.737  5.433   29.281 1   44.81  ? 351 LEU P C   1 
ATOM   4029  O  O   . LEU C 3 110 ? 19.91   5.572   29.659 1   45.3   ? 351 LEU P O   1 
ATOM   4030  C  CB  . LEU C 3 110 ? 17.934  7.765   29.942 1   45.63  ? 351 LEU P CB  1 
ATOM   4031  C  CG  . LEU C 3 110 ? 17.893  8.439   28.57  1   44.66  ? 351 LEU P CG  1 
ATOM   4032  C  CD1 . LEU C 3 110 ? 16.569  8.198   27.861 1   44.57  ? 351 LEU P CD1 1 
ATOM   4033  C  CD2 . LEU C 3 110 ? 18.14   9.933   28.706 1   44.62  ? 351 LEU P CD2 1 
ATOM   4034  N  N   . LEU C 3 111 ? 18.329  4.556   28.362 1   45.85  ? 352 LEU P N   1 
ATOM   4035  C  CA  . LEU C 3 111 ? 19.201  3.553   27.701 1   46.07  ? 352 LEU P CA  1 
ATOM   4036  C  C   . LEU C 3 111 ? 19.648  4.129   26.363 1   45.32  ? 352 LEU P C   1 
ATOM   4037  O  O   . LEU C 3 111 ? 18.824  4.66    25.624 1   41.93  ? 352 LEU P O   1 
ATOM   4038  C  CB  . LEU C 3 111 ? 18.427  2.241   27.522 1   46.78  ? 352 LEU P CB  1 
ATOM   4039  C  CG  . LEU C 3 111 ? 17.74   1.696   28.777 1   46.44  ? 352 LEU P CG  1 
ATOM   4040  C  CD1 . LEU C 3 111 ? 16.948  0.439   28.459 1   45.7   ? 352 LEU P CD1 1 
ATOM   4041  C  CD2 . LEU C 3 111 ? 18.744  1.423   29.886 1   46.73  ? 352 LEU P CD2 1 
ATOM   4042  N  N   . PRO C 3 112 ? 20.957  4.053   26.027 1   46.6   ? 353 PRO P N   1 
ATOM   4043  C  CA  . PRO C 3 112 ? 21.484  4.67    24.81  1   48.19  ? 353 PRO P CA  1 
ATOM   4044  C  C   . PRO C 3 112 ? 21.076  3.902   23.56  1   48.67  ? 353 PRO P C   1 
ATOM   4045  O  O   . PRO C 3 112 ? 20.563  2.794   23.67  1   50.67  ? 353 PRO P O   1 
ATOM   4046  C  CB  . PRO C 3 112 ? 23.004  4.61    25.01  1   48.79  ? 353 PRO P CB  1 
ATOM   4047  C  CG  . PRO C 3 112 ? 23.207  3.389   25.883 1   49.56  ? 353 PRO P CG  1 
ATOM   4048  C  CD  . PRO C 3 112 ? 22.002  3.361   26.799 1   47.89  ? 353 PRO P CD  1 
ATOM   4049  N  N   . PRO C 3 113 ? 21.305  4.442   22.341 1   51.46  ? 354 PRO P N   1 
ATOM   4050  C  CA  . PRO C 3 113 ? 20.851  3.776   21.125 1   54.03  ? 354 PRO P CA  1 
ATOM   4051  C  C   . PRO C 3 113 ? 21.67   2.51    20.893 1   56.06  ? 354 PRO P C   1 
ATOM   4052  O  O   . PRO C 3 113 ? 22.853  2.465   21.232 1   57.65  ? 354 PRO P O   1 
ATOM   4053  C  CB  . PRO C 3 113 ? 21.06   4.791   19.988 1   54.29  ? 354 PRO P CB  1 
ATOM   4054  C  CG  . PRO C 3 113 ? 21.588  6.056   20.654 1   54.25  ? 354 PRO P CG  1 
ATOM   4055  C  CD  . PRO C 3 113 ? 22.055  5.67    22.044 1   52.79  ? 354 PRO P CD  1 
ATOM   4056  N  N   . PRO C 3 114 ? 21.072  1.442   20.318 1   57.53  ? 355 PRO P N   1 
ATOM   4057  C  CA  . PRO C 3 114 ? 21.822  0.222   20.024 1   58.82  ? 355 PRO P CA  1 
ATOM   4058  C  C   . PRO C 3 114 ? 22.848  0.482   18.909 1   60.7   ? 355 PRO P C   1 
ATOM   4059  O  O   . PRO C 3 114 ? 22.597  1.345   18.082 1   61.69  ? 355 PRO P O   1 
ATOM   4060  C  CB  . PRO C 3 114 ? 20.73   -0.774  19.607 1   57.71  ? 355 PRO P CB  1 
ATOM   4061  C  CG  . PRO C 3 114 ? 19.616  0.096   19.058 1   57.1   ? 355 PRO P CG  1 
ATOM   4062  C  CD  . PRO C 3 114 ? 19.665  1.361   19.889 1   57.48  ? 355 PRO P CD  1 
ATOM   4063  N  N   . SER C 3 115 ? 23.97   -0.251  18.929 1   63.82  ? 356 SER P N   1 
ATOM   4064  C  CA  . SER C 3 115 ? 25.065  -0.22   17.916 1   64.63  ? 356 SER P CA  1 
ATOM   4065  C  C   . SER C 3 115 ? 24.495  -0.305  16.491 1   64.16  ? 356 SER P C   1 
ATOM   4066  O  O   . SER C 3 115 ? 24.993  0.428   15.613 1   62.89  ? 356 SER P O   1 
ATOM   4067  C  CB  . SER C 3 115 ? 26.058  -1.332  18.163 1   66.63  ? 356 SER P CB  1 
ATOM   4068  O  OG  . SER C 3 115 ? 26.38   -1.429  19.544 1   70.66  ? 356 SER P OG  1 
ATOM   4069  N  N   . GLU C 3 116 ? 23.483  -1.158  16.29  1   65.33  ? 357 GLU P N   1 
ATOM   4070  C  CA  . GLU C 3 116 ? 22.828  -1.45   14.983 1   68.51  ? 357 GLU P CA  1 
ATOM   4071  C  C   . GLU C 3 116 ? 22.416  -0.142  14.289 1   66.09  ? 357 GLU P C   1 
ATOM   4072  O  O   . GLU C 3 116 ? 22.754  0.021   13.103 1   65.11  ? 357 GLU P O   1 
ATOM   4073  C  CB  . GLU C 3 116 ? 21.597  -2.348  15.167 1   72.17  ? 357 GLU P CB  1 
ATOM   4074  C  CG  . GLU C 3 116 ? 21.87   -3.666  15.881 1   75.47  ? 357 GLU P CG  1 
ATOM   4075  C  CD  . GLU C 3 116 ? 21.442  -3.726  17.343 1   78.14  ? 357 GLU P CD  1 
ATOM   4076  O  OE1 . GLU C 3 116 ? 20.222  -3.846  17.602 1   73.29  ? 357 GLU P OE1 1 
ATOM   4077  O  OE2 . GLU C 3 116 ? 22.33   -3.644  18.224 1   78.88  ? 357 GLU P OE2 1 
ATOM   4078  N  N   . GLU C 3 117 ? 21.716  0.748   15.002 1   64.25  ? 358 GLU P N   1 
ATOM   4079  C  CA  . GLU C 3 117 ? 21.099  1.983   14.437 1   63.23  ? 358 GLU P CA  1 
ATOM   4080  C  C   . GLU C 3 117 ? 22.171  3.04    14.141 1   64.75  ? 358 GLU P C   1 
ATOM   4081  O  O   . GLU C 3 117 ? 22.051  3.716   13.094 1   64.47  ? 358 GLU P O   1 
ATOM   4082  C  CB  . GLU C 3 117 ? 20.049  2.558   15.391 1   60.86  ? 358 GLU P CB  1 
ATOM   4083  C  CG  . GLU C 3 117 ? 18.742  1.791   15.387 1   59.11  ? 358 GLU P CG  1 
ATOM   4084  C  CD  . GLU C 3 117 ? 17.626  2.473   16.157 1   58.26  ? 358 GLU P CD  1 
ATOM   4085  O  OE1 . GLU C 3 117 ? 17.928  3.065   17.22  1   56.48  ? 358 GLU P OE1 1 
ATOM   4086  O  OE2 . GLU C 3 117 ? 16.464  2.42    15.69  1   55.36  ? 358 GLU P OE2 1 
ATOM   4087  N  N   . LEU C 3 118 ? 23.148  3.195   15.043 1   65.58  ? 359 LEU P N   1 
ATOM   4088  C  CA  . LEU C 3 118 ? 24.27   4.171   14.936 1   68.57  ? 359 LEU P CA  1 
ATOM   4089  C  C   . LEU C 3 118 ? 25.023  3.961   13.616 1   70.86  ? 359 LEU P C   1 
ATOM   4090  O  O   . LEU C 3 118 ? 25.266  4.967   12.914 1   76.27  ? 359 LEU P O   1 
ATOM   4091  C  CB  . LEU C 3 118 ? 25.205  3.996   16.137 1   70.02  ? 359 LEU P CB  1 
ATOM   4092  C  CG  . LEU C 3 118 ? 24.646  4.501   17.466 1   71.6   ? 359 LEU P CG  1 
ATOM   4093  C  CD1 . LEU C 3 118 ? 25.299  3.796   18.646 1   74.02  ? 359 LEU P CD1 1 
ATOM   4094  C  CD2 . LEU C 3 118 ? 24.817  6.006   17.579 1   71.87  ? 359 LEU P CD2 1 
ATOM   4095  N  N   . ALA C 3 119 ? 25.362  2.704   13.304 1   68.33  ? 360 ALA P N   1 
ATOM   4096  C  CA  . ALA C 3 119 ? 26.06   2.256   12.073 1   67.36  ? 360 ALA P CA  1 
ATOM   4097  C  C   . ALA C 3 119 ? 25.315  2.722   10.813 1   68.11  ? 360 ALA P C   1 
ATOM   4098  O  O   . ALA C 3 119 ? 25.998  3.126   9.849  1   68.33  ? 360 ALA P O   1 
ATOM   4099  C  CB  . ALA C 3 119 ? 26.204  0.753   12.086 1   67.83  ? 360 ALA P CB  1 
ATOM   4100  N  N   . LEU C 3 120 ? 23.977  2.668   10.82  1   68.22  ? 361 LEU P N   1 
ATOM   4101  C  CA  . LEU C 3 120 ? 23.119  2.998   9.647  1   69.52  ? 361 LEU P CA  1 
ATOM   4102  C  C   . LEU C 3 120 ? 23.043  4.518   9.422  1   71.83  ? 361 LEU P C   1 
ATOM   4103  O  O   . LEU C 3 120 ? 22.6    4.903   8.32   1   71.37  ? 361 LEU P O   1 
ATOM   4104  C  CB  . LEU C 3 120 ? 21.726  2.39    9.845  1   71.65  ? 361 LEU P CB  1 
ATOM   4105  C  CG  . LEU C 3 120 ? 21.676  0.861   9.917  1   74.77  ? 361 LEU P CG  1 
ATOM   4106  C  CD1 . LEU C 3 120 ? 20.341  0.376   10.469 1   73.58  ? 361 LEU P CD1 1 
ATOM   4107  C  CD2 . LEU C 3 120 ? 21.945  0.233   8.555  1   75.72  ? 361 LEU P CD2 1 
ATOM   4108  N  N   . ASN C 3 121 ? 23.436  5.34    10.41  1   74.37  ? 362 ASN P N   1 
ATOM   4109  C  CA  . ASN C 3 121 ? 23.598  6.825   10.322 1   77.92  ? 362 ASN P CA  1 
ATOM   4110  C  C   . ASN C 3 121 ? 22.342  7.484   9.721  1   77.96  ? 362 ASN P C   1 
ATOM   4111  O  O   . ASN C 3 121 ? 22.494  8.393   8.871  1   81.9   ? 362 ASN P O   1 
ATOM   4112  C  CB  . ASN C 3 121 ? 24.885  7.213   9.577  1   78.24  ? 362 ASN P CB  1 
ATOM   4113  C  CG  . ASN C 3 121 ? 26.121  7.14    10.451 1   80.47  ? 362 ASN P CG  1 
ATOM   4114  O  OD1 . ASN C 3 121 ? 26.334  8.008   11.295 1   80.42  ? 362 ASN P OD1 1 
ATOM   4115  N  ND2 . ASN C 3 121 ? 26.944  6.12    10.26  1   82.72  ? 362 ASN P ND2 1 
ATOM   4116  N  N   . GLU C 3 122 ? 21.151  7.046   10.151 1   75.93  ? 363 GLU P N   1 
ATOM   4117  C  CA  . GLU C 3 122 ? 19.838  7.698   9.882  1   74.25  ? 363 GLU P CA  1 
ATOM   4118  C  C   . GLU C 3 122 ? 19.28   8.139   11.244 1   70.78  ? 363 GLU P C   1 
ATOM   4119  O  O   . GLU C 3 122 ? 20.043  8.782   11.991 1   68.06  ? 363 GLU P O   1 
ATOM   4120  C  CB  . GLU C 3 122 ? 18.942  6.754   9.071  1   77.62  ? 363 GLU P CB  1 
ATOM   4121  C  CG  . GLU C 3 122 ? 19.417  6.536   7.641  1   83.86  ? 363 GLU P CG  1 
ATOM   4122  C  CD  . GLU C 3 122 ? 19.181  7.684   6.666  1   87.07  ? 363 GLU P CD  1 
ATOM   4123  O  OE1 . GLU C 3 122 ? 19.831  7.693   5.598  1   88.04  ? 363 GLU P OE1 1 
ATOM   4124  O  OE2 . GLU C 3 122 ? 18.343  8.562   6.963  1   89.65  ? 363 GLU P OE2 1 
ATOM   4125  N  N   . LEU C 3 123 ? 18.026  7.813   11.58  1   67.82  ? 364 LEU P N   1 
ATOM   4126  C  CA  . LEU C 3 123 ? 17.458  8.049   12.934 1   63.56  ? 364 LEU P CA  1 
ATOM   4127  C  C   . LEU C 3 123 ? 17.972  6.963   13.891 1   58.4   ? 364 LEU P C   1 
ATOM   4128  O  O   . LEU C 3 123 ? 18.167  5.819   13.44  1   57.17  ? 364 LEU P O   1 
ATOM   4129  C  CB  . LEU C 3 123 ? 15.927  8.062   12.847 1   64.05  ? 364 LEU P CB  1 
ATOM   4130  C  CG  . LEU C 3 123 ? 15.327  9.213   12.035 1   65.86  ? 364 LEU P CG  1 
ATOM   4131  C  CD1 . LEU C 3 123 ? 13.864  8.949   11.707 1   65.26  ? 364 LEU P CD1 1 
ATOM   4132  C  CD2 . LEU C 3 123 ? 15.472  10.541  12.767 1   65.85  ? 364 LEU P CD2 1 
ATOM   4133  N  N   . VAL C 3 124 ? 18.223  7.332   15.151 1   54.32  ? 365 VAL P N   1 
ATOM   4134  C  CA  . VAL C 3 124 ? 18.578  6.406   16.269 1   53.53  ? 365 VAL P CA  1 
ATOM   4135  C  C   . VAL C 3 124 ? 17.532  6.574   17.378 1   52.38  ? 365 VAL P C   1 
ATOM   4136  O  O   . VAL C 3 124 ? 16.911  7.659   17.459 1   52.18  ? 365 VAL P O   1 
ATOM   4137  C  CB  . VAL C 3 124 ? 20.012  6.64    16.785 1   56.42  ? 365 VAL P CB  1 
ATOM   4138  C  CG1 . VAL C 3 124 ? 21.034  6.5     15.665 1   58.18  ? 365 VAL P CG1 1 
ATOM   4139  C  CG2 . VAL C 3 124 ? 20.185  7.98    17.491 1   56.6   ? 365 VAL P CG2 1 
ATOM   4140  N  N   . THR C 3 125 ? 17.366  5.543   18.209 1   49.83  ? 366 THR P N   1 
ATOM   4141  C  CA  . THR C 3 125 ? 16.232  5.385   19.157 1   46.76  ? 366 THR P CA  1 
ATOM   4142  C  C   . THR C 3 125 ? 16.751  5.438   20.598 1   46.49  ? 366 THR P C   1 
ATOM   4143  O  O   . THR C 3 125 ? 17.605  4.608   20.949 1   46.23  ? 366 THR P O   1 
ATOM   4144  C  CB  . THR C 3 125 ? 15.466  4.089   18.869 1   44.69  ? 366 THR P CB  1 
ATOM   4145  O  OG1 . THR C 3 125 ? 15.188  4.027   17.468 1   45.1   ? 366 THR P OG1 1 
ATOM   4146  C  CG2 . THR C 3 125 ? 14.164  4       19.631 1   44.11  ? 366 THR P CG2 1 
ATOM   4147  N  N   . LEU C 3 126 ? 16.245  6.386   21.392 1   46.16  ? 367 LEU P N   1 
ATOM   4148  C  CA  . LEU C 3 126 ? 16.496  6.491   22.854 1   45.4   ? 367 LEU P CA  1 
ATOM   4149  C  C   . LEU C 3 126 ? 15.281  5.917   23.586 1   42.76  ? 367 LEU P C   1 
ATOM   4150  O  O   . LEU C 3 126 ? 14.15   6.237   23.187 1   43.64  ? 367 LEU P O   1 
ATOM   4151  C  CB  . LEU C 3 126 ? 16.74   7.959   23.224 1   47.49  ? 367 LEU P CB  1 
ATOM   4152  C  CG  . LEU C 3 126 ? 17.893  8.637   22.485 1   48.91  ? 367 LEU P CG  1 
ATOM   4153  C  CD1 . LEU C 3 126 ? 17.868  10.133  22.707 1   50.82  ? 367 LEU P CD1 1 
ATOM   4154  C  CD2 . LEU C 3 126 ? 19.236  8.071   22.913 1   50.73  ? 367 LEU P CD2 1 
ATOM   4155  N  N   . THR C 3 127 ? 15.522  5.094   24.606 1   40.84  ? 368 THR P N   1 
ATOM   4156  C  CA  . THR C 3 127 ? 14.502  4.296   25.334 1   40.71  ? 368 THR P CA  1 
ATOM   4157  C  C   . THR C 3 127 ? 14.532  4.705   26.811 1   41.74  ? 368 THR P C   1 
ATOM   4158  O  O   . THR C 3 127 ? 15.562  4.448   27.468 1   40.68  ? 368 THR P O   1 
ATOM   4159  C  CB  . THR C 3 127 ? 14.75   2.794   25.127 1   40.21  ? 368 THR P CB  1 
ATOM   4160  O  OG1 . THR C 3 127 ? 14.922  2.552   23.729 1   39.5   ? 368 THR P OG1 1 
ATOM   4161  C  CG2 . THR C 3 127 ? 13.624  1.925   25.638 1   40.68  ? 368 THR P CG2 1 
ATOM   4162  N  N   . CYS C 3 128 ? 13.465  5.349   27.298 1   42.84  ? 369 CYS P N   1 
ATOM   4163  C  CA  . CYS C 3 128 ? 13.273  5.712   28.729 1   44.27  ? 369 CYS P CA  1 
ATOM   4164  C  C   . CYS C 3 128 ? 12.406  4.634   29.396 1   43.26  ? 369 CYS P C   1 
ATOM   4165  O  O   . CYS C 3 128 ? 11.317  4.333   28.868 1   40.77  ? 369 CYS P O   1 
ATOM   4166  C  CB  . CYS C 3 128 ? 12.663  7.104   28.88  1   45.77  ? 369 CYS P CB  1 
ATOM   4167  S  SG  . CYS C 3 128 ? 12.393  7.597   30.607 1   51.04  ? 369 CYS P SG  1 
ATOM   4168  N  N   . LEU C 3 129 ? 12.895  4.061   30.5   1   42.52  ? 370 LEU P N   1 
ATOM   4169  C  CA  . LEU C 3 129 ? 12.184  3.042   31.317 1   43.25  ? 370 LEU P CA  1 
ATOM   4170  C  C   . LEU C 3 129 ? 12.028  3.579   32.74  1   42.22  ? 370 LEU P C   1 
ATOM   4171  O  O   . LEU C 3 129 ? 13.054  3.696   33.439 1   42.16  ? 370 LEU P O   1 
ATOM   4172  C  CB  . LEU C 3 129 ? 12.983  1.733   31.3   1   43.54  ? 370 LEU P CB  1 
ATOM   4173  C  CG  . LEU C 3 129 ? 12.544  0.658   32.297 1   43.47  ? 370 LEU P CG  1 
ATOM   4174  C  CD1 . LEU C 3 129 ? 11.13   0.179   32.019 1   43.84  ? 370 LEU P CD1 1 
ATOM   4175  C  CD2 . LEU C 3 129 ? 13.51   -0.508  32.266 1   45.04  ? 370 LEU P CD2 1 
ATOM   4176  N  N   . ALA C 3 130 ? 10.793  3.899   33.132 1   41.76  ? 371 ALA P N   1 
ATOM   4177  C  CA  . ALA C 3 130 ? 10.382  4.107   34.539 1   41.61  ? 371 ALA P CA  1 
ATOM   4178  C  C   . ALA C 3 130 ? 9.789   2.788   35.042 1   40.74  ? 371 ALA P C   1 
ATOM   4179  O  O   . ALA C 3 130 ? 8.983   2.187   34.311 1   39.44  ? 371 ALA P O   1 
ATOM   4180  C  CB  . ALA C 3 130 ? 9.41    5.259   34.647 1   40.77  ? 371 ALA P CB  1 
ATOM   4181  N  N   . ARG C 3 131 ? 10.181  2.36    36.241 1   42.82  ? 372 ARG P N   1 
ATOM   4182  C  CA  . ARG C 3 131 ? 9.972   0.975   36.743 1   44.58  ? 372 ARG P CA  1 
ATOM   4183  C  C   . ARG C 3 131 ? 9.877   0.994   38.273 1   44.95  ? 372 ARG P C   1 
ATOM   4184  O  O   . ARG C 3 131 ? 10.651  1.736   38.897 1   46.71  ? 372 ARG P O   1 
ATOM   4185  C  CB  . ARG C 3 131 ? 11.139  0.099   36.269 1   46.08  ? 372 ARG P CB  1 
ATOM   4186  C  CG  . ARG C 3 131 ? 10.859  -1.396  36.298 1   48.63  ? 372 ARG P CG  1 
ATOM   4187  C  CD  . ARG C 3 131 ? 12.068  -2.226  36.692 1   48.97  ? 372 ARG P CD  1 
ATOM   4188  N  NE  . ARG C 3 131 ? 12.456  -1.955  38.067 1   49.24  ? 372 ARG P NE  1 
ATOM   4189  C  CZ  . ARG C 3 131 ? 11.807  -2.368  39.157 1   50.54  ? 372 ARG P CZ  1 
ATOM   4190  N  NH1 . ARG C 3 131 ? 10.714  -3.11   39.065 1   48.71  ? 372 ARG P NH1 1 
ATOM   4191  N  NH2 . ARG C 3 131 ? 12.263  -2.033  40.354 1   54.4   ? 372 ARG P NH2 1 
ATOM   4192  N  N   . GLY C 3 132 ? 8.957   0.216   38.85  1   46.31  ? 373 GLY P N   1 
ATOM   4193  C  CA  . GLY C 3 132 ? 8.934   -0.099  40.292 1   47.5   ? 373 GLY P CA  1 
ATOM   4194  C  C   . GLY C 3 132 ? 8.071   0.854   41.104 1   49.86  ? 373 GLY P C   1 
ATOM   4195  O  O   . GLY C 3 132 ? 8.252   0.873   42.333 1   51     ? 373 GLY P O   1 
ATOM   4196  N  N   . PHE C 3 133 ? 7.135   1.574   40.471 1   51.47  ? 374 PHE P N   1 
ATOM   4197  C  CA  . PHE C 3 133 ? 6.323   2.655   41.1   1   53.57  ? 374 PHE P CA  1 
ATOM   4198  C  C   . PHE C 3 133 ? 4.909   2.129   41.394 1   58.28  ? 374 PHE P C   1 
ATOM   4199  O  O   . PHE C 3 133 ? 4.347   1.412   40.539 1   58.21  ? 374 PHE P O   1 
ATOM   4200  C  CB  . PHE C 3 133 ? 6.351   3.934   40.25  1   51.6   ? 374 PHE P CB  1 
ATOM   4201  C  CG  . PHE C 3 133 ? 5.947   3.815   38.798 1   48.38  ? 374 PHE P CG  1 
ATOM   4202  C  CD1 . PHE C 3 133 ? 4.623   3.976   38.422 1   46.71  ? 374 PHE P CD1 1 
ATOM   4203  C  CD2 . PHE C 3 133 ? 6.887   3.592   37.8   1   48.33  ? 374 PHE P CD2 1 
ATOM   4204  C  CE1 . PHE C 3 133 ? 4.24    3.888   37.093 1   46.04  ? 374 PHE P CE1 1 
ATOM   4205  C  CE2 . PHE C 3 133 ? 6.503   3.507   36.468 1   48.3   ? 374 PHE P CE2 1 
ATOM   4206  C  CZ  . PHE C 3 133 ? 5.18    3.655   36.116 1   47.32  ? 374 PHE P CZ  1 
ATOM   4207  N  N   . SER C 3 134 ? 4.357   2.452   42.574 1   65.4   ? 375 SER P N   1 
ATOM   4208  C  CA  . SER C 3 134 ? 3.173   1.756   43.158 1   71.15  ? 375 SER P CA  1 
ATOM   4209  C  C   . SER C 3 134 ? 1.865   2.281   42.576 1   71.35  ? 375 SER P C   1 
ATOM   4210  O  O   . SER C 3 134 ? 1.017   1.471   42.208 1   80.05  ? 375 SER P O   1 
ATOM   4211  C  CB  . SER C 3 134 ? 3.129   1.801   44.661 1   74.85  ? 375 SER P CB  1 
ATOM   4212  O  OG  . SER C 3 134 ? 2.02    1.054   45.152 1   77.54  ? 375 SER P OG  1 
ATOM   4213  N  N   . PRO C 3 135 ? 1.607   3.61    42.527 1   63.24  ? 376 PRO P N   1 
ATOM   4214  C  CA  . PRO C 3 135 ? 0.441   4.121   41.807 1   59.67  ? 376 PRO P CA  1 
ATOM   4215  C  C   . PRO C 3 135 ? 0.763   4.128   40.302 1   56.97  ? 376 PRO P C   1 
ATOM   4216  O  O   . PRO C 3 135 ? 1.794   4.63    39.929 1   54.02  ? 376 PRO P O   1 
ATOM   4217  C  CB  . PRO C 3 135 ? 0.201   5.519   42.403 1   58.77  ? 376 PRO P CB  1 
ATOM   4218  C  CG  . PRO C 3 135 ? 1.242   5.662   43.509 1   60.3   ? 376 PRO P CG  1 
ATOM   4219  C  CD  . PRO C 3 135 ? 2.357   4.693   43.174 1   59.6   ? 376 PRO P CD  1 
ATOM   4220  N  N   . LYS C 3 136 ? -0.125  3.557   39.487 1   57.37  ? 377 LYS P N   1 
ATOM   4221  C  CA  . LYS C 3 136 ? -0.013  3.469   38.001 1   59.97  ? 377 LYS P CA  1 
ATOM   4222  C  C   . LYS C 3 136 ? 0.312   4.845   37.389 1   56.74  ? 377 LYS P C   1 
ATOM   4223  O  O   . LYS C 3 136 ? 0.983   4.869   36.338 1   55.37  ? 377 LYS P O   1 
ATOM   4224  C  CB  . LYS C 3 136 ? -1.304  2.845   37.442 1   65.44  ? 377 LYS P CB  1 
ATOM   4225  C  CG  . LYS C 3 136 ? -1.775  3.322   36.075 1   72.72  ? 377 LYS P CG  1 
ATOM   4226  C  CD  . LYS C 3 136 ? -2.952  2.536   35.537 1   76.93  ? 377 LYS P CD  1 
ATOM   4227  C  CE  . LYS C 3 136 ? -3.446  3.067   34.206 1   82.85  ? 377 LYS P CE  1 
ATOM   4228  N  NZ  . LYS C 3 136 ? -4.61   2.299   33.702 1   84     ? 377 LYS P NZ  1 
ATOM   4229  N  N   . ASP C 3 137 ? -0.139  5.941   38.011 1   52.71  ? 378 ASP P N   1 
ATOM   4230  C  CA  . ASP C 3 137 ? -0.143  7.304   37.414 1   51.48  ? 378 ASP P CA  1 
ATOM   4231  C  C   . ASP C 3 137 ? 1.291   7.831   37.319 1   49.67  ? 378 ASP P C   1 
ATOM   4232  O  O   . ASP C 3 137 ? 1.993   7.851   38.353 1   48.45  ? 378 ASP P O   1 
ATOM   4233  C  CB  . ASP C 3 137 ? -1.069  8.231   38.198 1   52.64  ? 378 ASP P CB  1 
ATOM   4234  C  CG  . ASP C 3 137 ? -2.477  7.674   38.257 1   53.1   ? 378 ASP P CG  1 
ATOM   4235  O  OD1 . ASP C 3 137 ? -3.219  7.867   37.273 1   51.18  ? 378 ASP P OD1 1 
ATOM   4236  O  OD2 . ASP C 3 137 ? -2.787  6.994   39.257 1   54.55  ? 378 ASP P OD2 1 
ATOM   4237  N  N   . VAL C 3 138 ? 1.69    8.243   36.111 1   46.85  ? 379 VAL P N   1 
ATOM   4238  C  CA  . VAL C 3 138 ? 3.089   8.623   35.757 1   46.01  ? 379 VAL P CA  1 
ATOM   4239  C  C   . VAL C 3 138 ? 3.054   9.581   34.557 1   44.75  ? 379 VAL P C   1 
ATOM   4240  O  O   . VAL C 3 138 ? 2.27    9.336   33.617 1   44.1   ? 379 VAL P O   1 
ATOM   4241  C  CB  . VAL C 3 138 ? 3.947   7.368   35.479 1   45.53  ? 379 VAL P CB  1 
ATOM   4242  C  CG1 . VAL C 3 138 ? 3.475   6.576   34.267 1   44.88  ? 379 VAL P CG1 1 
ATOM   4243  C  CG2 . VAL C 3 138 ? 5.423   7.705   35.344 1   46.81  ? 379 VAL P CG2 1 
ATOM   4244  N  N   . LEU C 3 139 ? 3.865   10.639  34.604 1   44.32  ? 380 LEU P N   1 
ATOM   4245  C  CA  . LEU C 3 139 ? 4.142   11.539  33.453 1   44.08  ? 380 LEU P CA  1 
ATOM   4246  C  C   . LEU C 3 139 ? 5.524   11.199  32.905 1   41.79  ? 380 LEU P C   1 
ATOM   4247  O  O   . LEU C 3 139 ? 6.436   10.979  33.723 1   39.71  ? 380 LEU P O   1 
ATOM   4248  C  CB  . LEU C 3 139 ? 4.102   13      33.909 1   45.42  ? 380 LEU P CB  1 
ATOM   4249  C  CG  . LEU C 3 139 ? 2.813   13.448  34.592 1   46.91  ? 380 LEU P CG  1 
ATOM   4250  C  CD1 . LEU C 3 139 ? 2.934   14.887  35.056 1   47.6   ? 380 LEU P CD1 1 
ATOM   4251  C  CD2 . LEU C 3 139 ? 1.611   13.284  33.673 1   47.45  ? 380 LEU P CD2 1 
ATOM   4252  N  N   . VAL C 3 140 ? 5.665   11.177  31.58  1   40.47  ? 381 VAL P N   1 
ATOM   4253  C  CA  . VAL C 3 140 ? 6.98    11.05   30.89  1   40.72  ? 381 VAL P CA  1 
ATOM   4254  C  C   . VAL C 3 140 ? 7.128   12.222  29.914 1   40.74  ? 381 VAL P C   1 
ATOM   4255  O  O   . VAL C 3 140 ? 6.222   12.409  29.077 1   40.7   ? 381 VAL P O   1 
ATOM   4256  C  CB  . VAL C 3 140 ? 7.123   9.689   30.184 1   39.08  ? 381 VAL P CB  1 
ATOM   4257  C  CG1 . VAL C 3 140 ? 8.454   9.58    29.46  1   39.2   ? 381 VAL P CG1 1 
ATOM   4258  C  CG2 . VAL C 3 140 ? 6.96    8.535   31.161 1   38.71  ? 381 VAL P CG2 1 
ATOM   4259  N  N   . ARG C 3 141 ? 8.243   12.95   30.015 1   42.38  ? 382 ARG P N   1 
ATOM   4260  C  CA  . ARG C 3 141 ? 8.592   14.125  29.17  1   43.88  ? 382 ARG P CA  1 
ATOM   4261  C  C   . ARG C 3 141 ? 10.072  14.048  28.791 1   41.58  ? 382 ARG P C   1 
ATOM   4262  O  O   . ARG C 3 141 ? 10.837  13.442  29.557 1   40.71  ? 382 ARG P O   1 
ATOM   4263  C  CB  . ARG C 3 141 ? 8.257   15.414  29.924 1   47.63  ? 382 ARG P CB  1 
ATOM   4264  C  CG  . ARG C 3 141 ? 6.789   15.799  29.83  1   50.58  ? 382 ARG P CG  1 
ATOM   4265  C  CD  . ARG C 3 141 ? 6.241   16.419  31.097 1   54.85  ? 382 ARG P CD  1 
ATOM   4266  N  NE  . ARG C 3 141 ? 4.881   16.917  30.913 1   58.91  ? 382 ARG P NE  1 
ATOM   4267  C  CZ  . ARG C 3 141 ? 4.206   17.667  31.789 1   62.6   ? 382 ARG P CZ  1 
ATOM   4268  N  NH1 . ARG C 3 141 ? 4.748   18.023  32.946 1   63.21  ? 382 ARG P NH1 1 
ATOM   4269  N  NH2 . ARG C 3 141 ? 2.976   18.063  31.501 1   63.55  ? 382 ARG P NH2 1 
ATOM   4270  N  N   . TRP C 3 142 ? 10.439  14.631  27.646 1   41.91  ? 383 TRP P N   1 
ATOM   4271  C  CA  . TRP C 3 142 ? 11.799  14.567  27.047 1   42.6   ? 383 TRP P CA  1 
ATOM   4272  C  C   . TRP C 3 142 ? 12.379  15.973  26.876 1   43.52  ? 383 TRP P C   1 
ATOM   4273  O  O   . TRP C 3 142 ? 11.608  16.887  26.512 1   42.71  ? 383 TRP P O   1 
ATOM   4274  C  CB  . TRP C 3 142 ? 11.762  13.839  25.698 1   44.04  ? 383 TRP P CB  1 
ATOM   4275  C  CG  . TRP C 3 142 ? 11.503  12.368  25.795 1   46.08  ? 383 TRP P CG  1 
ATOM   4276  C  CD1 . TRP C 3 142 ? 10.292  11.763  25.941 1   46.13  ? 383 TRP P CD1 1 
ATOM   4277  C  CD2 . TRP C 3 142 ? 12.476  11.308  25.746 1   46.06  ? 383 TRP P CD2 1 
ATOM   4278  N  NE1 . TRP C 3 142 ? 10.442  10.407  25.985 1   46.95  ? 383 TRP P NE1 1 
ATOM   4279  C  CE2 . TRP C 3 142 ? 11.769  10.094  25.871 1   45.8   ? 383 TRP P CE2 1 
ATOM   4280  C  CE3 . TRP C 3 142 ? 13.869  11.261  25.614 1   47.06  ? 383 TRP P CE3 1 
ATOM   4281  C  CZ2 . TRP C 3 142 ? 12.406  8.852   25.858 1   46.84  ? 383 TRP P CZ2 1 
ATOM   4282  C  CZ3 . TRP C 3 142 ? 14.499  10.035  25.597 1   49.29  ? 383 TRP P CZ3 1 
ATOM   4283  C  CH2 . TRP C 3 142 ? 13.776  8.844   25.722 1   47.49  ? 383 TRP P CH2 1 
ATOM   4284  N  N   . LEU C 3 143 ? 13.691  16.114  27.109 1   42.7   ? 384 LEU P N   1 
ATOM   4285  C  CA  . LEU C 3 143 ? 14.531  17.237  26.613 1   42.9   ? 384 LEU P CA  1 
ATOM   4286  C  C   . LEU C 3 143 ? 15.468  16.732  25.508 1   44.73  ? 384 LEU P C   1 
ATOM   4287  O  O   . LEU C 3 143 ? 15.945  15.581  25.609 1   47.1   ? 384 LEU P O   1 
ATOM   4288  C  CB  . LEU C 3 143 ? 15.374  17.82   27.75  1   42.53  ? 384 LEU P CB  1 
ATOM   4289  C  CG  . LEU C 3 143 ? 14.65   18.159  29.049 1   42.6   ? 384 LEU P CG  1 
ATOM   4290  C  CD1 . LEU C 3 143 ? 15.655  18.567  30.113 1   43.72  ? 384 LEU P CD1 1 
ATOM   4291  C  CD2 . LEU C 3 143 ? 13.622  19.257  28.844 1   41.54  ? 384 LEU P CD2 1 
ATOM   4292  N  N   . GLN C 3 144 ? 15.713  17.568  24.495 1   45.51  ? 385 GLN P N   1 
ATOM   4293  C  CA  . GLN C 3 144 ? 16.975  17.601  23.705 1   44.86  ? 385 GLN P CA  1 
ATOM   4294  C  C   . GLN C 3 144 ? 17.671  18.922  24.046 1   42.67  ? 385 GLN P C   1 
ATOM   4295  O  O   . GLN C 3 144 ? 17.066  19.987  23.804 1   40.45  ? 385 GLN P O   1 
ATOM   4296  C  CB  . GLN C 3 144 ? 16.716  17.477  22.203 1   46.8   ? 385 GLN P CB  1 
ATOM   4297  C  CG  . GLN C 3 144 ? 17.995  17.469  21.372 1   47.52  ? 385 GLN P CG  1 
ATOM   4298  C  CD  . GLN C 3 144 ? 17.743  17.343  19.888 1   48.85  ? 385 GLN P CD  1 
ATOM   4299  O  OE1 . GLN C 3 144 ? 16.605  17.235  19.432 1   49.98  ? 385 GLN P OE1 1 
ATOM   4300  N  NE2 . GLN C 3 144 ? 18.815  17.38   19.115 1   49.61  ? 385 GLN P NE2 1 
ATOM   4301  N  N   . GLY C 3 145 ? 18.884  18.847  24.598 1   42.45  ? 386 GLY P N   1 
ATOM   4302  C  CA  . GLY C 3 145 ? 19.562  19.984  25.243 1   43.31  ? 386 GLY P CA  1 
ATOM   4303  C  C   . GLY C 3 145 ? 18.746  20.479  26.425 1   44.03  ? 386 GLY P C   1 
ATOM   4304  O  O   . GLY C 3 145 ? 18.336  19.643  27.261 1   43.02  ? 386 GLY P O   1 
ATOM   4305  N  N   . SER C 3 146 ? 18.482  21.785  26.467 1   43.32  ? 387 SER P N   1 
ATOM   4306  C  CA  . SER C 3 146 ? 17.597  22.444  27.458 1   41.9   ? 387 SER P CA  1 
ATOM   4307  C  C   . SER C 3 146 ? 16.207  22.689  26.852 1   41.7   ? 387 SER P C   1 
ATOM   4308  O  O   . SER C 3 146 ? 15.375  23.272  27.562 1   40.6   ? 387 SER P O   1 
ATOM   4309  C  CB  . SER C 3 146 ? 18.232  23.714  27.956 1   41.93  ? 387 SER P CB  1 
ATOM   4310  O  OG  . SER C 3 146 ? 18.713  24.497  26.875 1   41.49  ? 387 SER P OG  1 
ATOM   4311  N  N   . GLN C 3 147 ? 15.961  22.265  25.603 1   42.68  ? 388 GLN P N   1 
ATOM   4312  C  CA  . GLN C 3 147 ? 14.625  22.344  24.944 1   44.67  ? 388 GLN P CA  1 
ATOM   4313  C  C   . GLN C 3 147 ? 13.813  21.092  25.296 1   46.38  ? 388 GLN P C   1 
ATOM   4314  O  O   . GLN C 3 147 ? 14.272  19.98   24.976 1   45.97  ? 388 GLN P O   1 
ATOM   4315  C  CB  . GLN C 3 147 ? 14.733  22.455  23.418 1   45.77  ? 388 GLN P CB  1 
ATOM   4316  C  CG  . GLN C 3 147 ? 13.422  22.811  22.719 1   47.1   ? 388 GLN P CG  1 
ATOM   4317  C  CD  . GLN C 3 147 ? 12.85   24.14   23.163 1   51.28  ? 388 GLN P CD  1 
ATOM   4318  O  OE1 . GLN C 3 147 ? 13.433  25.197  22.932 1   55.59  ? 388 GLN P OE1 1 
ATOM   4319  N  NE2 . GLN C 3 147 ? 11.697  24.107  23.815 1   52.33  ? 388 GLN P NE2 1 
ATOM   4320  N  N   . GLU C 3 148 ? 12.642  21.277  25.908 1   47.69  ? 389 GLU P N   1 
ATOM   4321  C  CA  . GLU C 3 148 ? 11.588  20.236  26.009 1   46.54  ? 389 GLU P CA  1 
ATOM   4322  C  C   . GLU C 3 148 ? 11.006  19.97   24.622 1   47.22  ? 389 GLU P C   1 
ATOM   4323  O  O   . GLU C 3 148 ? 10.586  20.941  23.975 1   45.94  ? 389 GLU P O   1 
ATOM   4324  C  CB  . GLU C 3 148 ? 10.457  20.679  26.93  1   46.53  ? 389 GLU P CB  1 
ATOM   4325  C  CG  . GLU C 3 148 ? 9.246   19.771  26.873 1   46.44  ? 389 GLU P CG  1 
ATOM   4326  C  CD  . GLU C 3 148 ? 8.286   20.006  28.015 1   47.32  ? 389 GLU P CD  1 
ATOM   4327  O  OE1 . GLU C 3 148 ? 7.696   19.023  28.498 1   50.33  ? 389 GLU P OE1 1 
ATOM   4328  O  OE2 . GLU C 3 148 ? 8.146   21.176  28.422 1   47.96  ? 389 GLU P OE2 1 
ATOM   4329  N  N   . LEU C 3 149 ? 10.925  18.698  24.224 1   49.63  ? 390 LEU P N   1 
ATOM   4330  C  CA  . LEU C 3 149 ? 10.345  18.276  22.923 1   51.2   ? 390 LEU P CA  1 
ATOM   4331  C  C   . LEU C 3 149 ? 8.828   18.215  23.061 1   51.36  ? 390 LEU P C   1 
ATOM   4332  O  O   . LEU C 3 149 ? 8.327   17.884  24.133 1   50.74  ? 390 LEU P O   1 
ATOM   4333  C  CB  . LEU C 3 149 ? 10.926  16.916  22.518 1   51.67  ? 390 LEU P CB  1 
ATOM   4334  C  CG  . LEU C 3 149 ? 12.445  16.868  22.368 1   51.31  ? 390 LEU P CG  1 
ATOM   4335  C  CD1 . LEU C 3 149 ? 12.901  15.47   22.017 1   51.18  ? 390 LEU P CD1 1 
ATOM   4336  C  CD2 . LEU C 3 149 ? 12.932  17.85   21.313 1   52.75  ? 390 LEU P CD2 1 
ATOM   4337  N  N   . PRO C 3 150 ? 8.05    18.563  22.008 1   52.55  ? 391 PRO P N   1 
ATOM   4338  C  CA  . PRO C 3 150 ? 6.599   18.363  22.027 1   54.03  ? 391 PRO P CA  1 
ATOM   4339  C  C   . PRO C 3 150 ? 6.178   16.89   22.177 1   53.79  ? 391 PRO P C   1 
ATOM   4340  O  O   . PRO C 3 150 ? 6.91    16.025  21.724 1   50.11  ? 391 PRO P O   1 
ATOM   4341  C  CB  . PRO C 3 150 ? 6.133   18.908  20.664 1   54.83  ? 391 PRO P CB  1 
ATOM   4342  C  CG  . PRO C 3 150 ? 7.238   19.841  20.224 1   53.84  ? 391 PRO P CG  1 
ATOM   4343  C  CD  . PRO C 3 150 ? 8.505   19.225  20.775 1   53.23  ? 391 PRO P CD  1 
ATOM   4344  N  N   . ARG C 3 151 ? 5.003   16.659  22.781 1   56.33  ? 392 ARG P N   1 
ATOM   4345  C  CA  . ARG C 3 151 ? 4.384   15.321  23.021 1   58.51  ? 392 ARG P CA  1 
ATOM   4346  C  C   . ARG C 3 151 ? 4.448   14.467  21.749 1   60.23  ? 392 ARG P C   1 
ATOM   4347  O  O   . ARG C 3 151 ? 4.818   13.282  21.859 1   61.1   ? 392 ARG P O   1 
ATOM   4348  C  CB  . ARG C 3 151 ? 2.919   15.45   23.466 1   59.44  ? 392 ARG P CB  1 
ATOM   4349  C  CG  . ARG C 3 151 ? 2.724   15.65   24.964 1   62.05  ? 392 ARG P CG  1 
ATOM   4350  C  CD  . ARG C 3 151 ? 1.371   16.104  25.39  0   61.69  ? 392 ARG P CD  1 
ATOM   4351  N  NE  . ARG C 3 151 ? 1.355   16.749  26.698 0   61.73  ? 392 ARG P NE  1 
ATOM   4352  C  CZ  . ARG C 3 151 ? 0.252   17.086  27.357 0   61.66  ? 392 ARG P CZ  1 
ATOM   4353  N  NH1 . ARG C 3 151 ? -0.936  16.833  26.835 0   61.63  ? 392 ARG P NH1 1 
ATOM   4354  N  NH2 . ARG C 3 151 ? 0.341   17.671  28.538 0   61.62  ? 392 ARG P NH2 1 
ATOM   4355  N  N   . GLU C 3 152 ? 4.14    15.059  20.589 1   60.84  ? 393 GLU P N   1 
ATOM   4356  C  CA  . GLU C 3 152 ? 3.911   14.329  19.308 1   63.66  ? 393 GLU P CA  1 
ATOM   4357  C  C   . GLU C 3 152 ? 5.242   13.981  18.617 1   62.06  ? 393 GLU P C   1 
ATOM   4358  O  O   . GLU C 3 152 ? 5.179   13.389  17.521 1   60.88  ? 393 GLU P O   1 
ATOM   4359  C  CB  . GLU C 3 152 ? 2.949   15.085  18.378 1   66.45  ? 393 GLU P CB  1 
ATOM   4360  C  CG  . GLU C 3 152 ? 3.158   16.591  18.289 1   70.71  ? 393 GLU P CG  1 
ATOM   4361  C  CD  . GLU C 3 152 ? 2.371   17.429  19.293 1   75.53  ? 393 GLU P CD  1 
ATOM   4362  O  OE1 . GLU C 3 152 ? 2.978   18.339  19.902 1   74.96  ? 393 GLU P OE1 1 
ATOM   4363  O  OE2 . GLU C 3 152 ? 1.153   17.176  19.469 1   75.96  ? 393 GLU P OE2 1 
ATOM   4364  N  N   . LYS C 3 153 ? 6.393   14.282  19.234 1   62.89  ? 394 LYS P N   1 
ATOM   4365  C  CA  . LYS C 3 153 ? 7.746   13.924  18.72  1   62.7   ? 394 LYS P CA  1 
ATOM   4366  C  C   . LYS C 3 153 ? 8.286   12.668  19.426 1   57.68  ? 394 LYS P C   1 
ATOM   4367  O  O   . LYS C 3 153 ? 9.424   12.264  19.096 1   52.95  ? 394 LYS P O   1 
ATOM   4368  C  CB  . LYS C 3 153 ? 8.71    15.106  18.889 1   66.87  ? 394 LYS P CB  1 
ATOM   4369  C  CG  . LYS C 3 153 ? 8.281   16.418  18.234 1   72.41  ? 394 LYS P CG  1 
ATOM   4370  C  CD  . LYS C 3 153 ? 8.131   16.376  16.72  1   74.74  ? 394 LYS P CD  1 
ATOM   4371  C  CE  . LYS C 3 153 ? 9.446   16.195  15.991 1   77.57  ? 394 LYS P CE  1 
ATOM   4372  N  NZ  . LYS C 3 153 ? 9.268   16.234  14.519 1   79.41  ? 394 LYS P NZ  1 
ATOM   4373  N  N   . TYR C 3 154 ? 7.528   12.063  20.354 1   52.37  ? 395 TYR P N   1 
ATOM   4374  C  CA  . TYR C 3 154 ? 7.925   10.807  21.045 1   49.12  ? 395 TYR P CA  1 
ATOM   4375  C  C   . TYR C 3 154 ? 6.699   9.935   21.35  1   47.75  ? 395 TYR P C   1 
ATOM   4376  O  O   . TYR C 3 154 ? 5.566   10.444  21.42  1   47.1   ? 395 TYR P O   1 
ATOM   4377  C  CB  . TYR C 3 154 ? 8.764   11.109  22.293 1   48.01  ? 395 TYR P CB  1 
ATOM   4378  C  CG  . TYR C 3 154 ? 8.133   12.01   23.326 1   47.19  ? 395 TYR P CG  1 
ATOM   4379  C  CD1 . TYR C 3 154 ? 7.306   11.5    24.319 1   47.06  ? 395 TYR P CD1 1 
ATOM   4380  C  CD2 . TYR C 3 154 ? 8.405   13.369  23.351 1   46.14  ? 395 TYR P CD2 1 
ATOM   4381  C  CE1 . TYR C 3 154 ? 6.74    12.317  25.285 1   45.23  ? 395 TYR P CE1 1 
ATOM   4382  C  CE2 . TYR C 3 154 ? 7.851   14.2    24.313 1   46.81  ? 395 TYR P CE2 1 
ATOM   4383  C  CZ  . TYR C 3 154 ? 7.015   13.673  25.283 1   46.16  ? 395 TYR P CZ  1 
ATOM   4384  O  OH  . TYR C 3 154 ? 6.464   14.487  26.227 1   46.95  ? 395 TYR P OH  1 
ATOM   4385  N  N   . LEU C 3 155 ? 6.942   8.631   21.504 1   46.76  ? 396 LEU P N   1 
ATOM   4386  C  CA  . LEU C 3 155 ? 5.916   7.595   21.786 1   45.42  ? 396 LEU P CA  1 
ATOM   4387  C  C   . LEU C 3 155 ? 6.086   7.117   23.228 1   44.91  ? 396 LEU P C   1 
ATOM   4388  O  O   . LEU C 3 155 ? 7.171   6.59    23.542 1   44.6   ? 396 LEU P O   1 
ATOM   4389  C  CB  . LEU C 3 155 ? 6.096   6.437   20.8   1   46.04  ? 396 LEU P CB  1 
ATOM   4390  C  CG  . LEU C 3 155 ? 5.223   5.207   21.047 1   47.4   ? 396 LEU P CG  1 
ATOM   4391  C  CD1 . LEU C 3 155 ? 3.743   5.562   21.002 1   48.47  ? 396 LEU P CD1 1 
ATOM   4392  C  CD2 . LEU C 3 155 ? 5.543   4.117   20.038 1   47.76  ? 396 LEU P CD2 1 
ATOM   4393  N  N   . THR C 3 156 ? 5.051   7.289   24.057 1   44.59  ? 397 THR P N   1 
ATOM   4394  C  CA  . THR C 3 156 ? 4.986   6.785   25.455 1   43.46  ? 397 THR P CA  1 
ATOM   4395  C  C   . THR C 3 156 ? 3.889   5.718   25.549 1   42.03  ? 397 THR P C   1 
ATOM   4396  O  O   . THR C 3 156 ? 2.75    5.997   25.141 1   42.21  ? 397 THR P O   1 
ATOM   4397  C  CB  . THR C 3 156 ? 4.781   7.936   26.444 1   42.97  ? 397 THR P CB  1 
ATOM   4398  O  OG1 . THR C 3 156 ? 5.837   8.869   26.218 1   42.75  ? 397 THR P OG1 1 
ATOM   4399  C  CG2 . THR C 3 156 ? 4.796   7.495   27.893 1   44.08  ? 397 THR P CG2 1 
ATOM   4400  N  N   . TRP C 3 157 ? 4.223   4.538   26.074 1   41.88  ? 398 TRP P N   1 
ATOM   4401  C  CA  . TRP C 3 157 ? 3.259   3.425   26.277 1   41.99  ? 398 TRP P CA  1 
ATOM   4402  C  C   . TRP C 3 157 ? 2.45    3.695   27.549 1   42.99  ? 398 TRP P C   1 
ATOM   4403  O  O   . TRP C 3 157 ? 2.823   4.612   28.314 1   42.04  ? 398 TRP P O   1 
ATOM   4404  C  CB  . TRP C 3 157 ? 3.983   2.067   26.288 1   40.45  ? 398 TRP P CB  1 
ATOM   4405  C  CG  . TRP C 3 157 ? 4.371   1.629   24.911 1   38.32  ? 398 TRP P CG  1 
ATOM   4406  C  CD1 . TRP C 3 157 ? 3.614   0.894   24.049 1   39.23  ? 398 TRP P CD1 1 
ATOM   4407  C  CD2 . TRP C 3 157 ? 5.574   1.958   24.197 1   38.2   ? 398 TRP P CD2 1 
ATOM   4408  N  NE1 . TRP C 3 157 ? 4.271   0.721   22.859 1   38.28  ? 398 TRP P NE1 1 
ATOM   4409  C  CE2 . TRP C 3 157 ? 5.478   1.361   22.92  1   38.57  ? 398 TRP P CE2 1 
ATOM   4410  C  CE3 . TRP C 3 157 ? 6.728   2.684   24.509 1   38.26  ? 398 TRP P CE3 1 
ATOM   4411  C  CZ2 . TRP C 3 157 ? 6.492   1.468   21.966 1   38.28  ? 398 TRP P CZ2 1 
ATOM   4412  C  CZ3 . TRP C 3 157 ? 7.729   2.792   23.565 1   38.56  ? 398 TRP P CZ3 1 
ATOM   4413  C  CH2 . TRP C 3 157 ? 7.614   2.188   22.312 1   37.69  ? 398 TRP P CH2 1 
ATOM   4414  N  N   . ALA C 3 158 ? 1.357   2.955   27.74  1   44.55  ? 399 ALA P N   1 
ATOM   4415  C  CA  . ALA C 3 158 ? 0.515   3.014   28.957 1   46.87  ? 399 ALA P CA  1 
ATOM   4416  C  C   . ALA C 3 158 ? 1.271   2.367   30.118 1   45.69  ? 399 ALA P C   1 
ATOM   4417  O  O   . ALA C 3 158 ? 2.028   1.425   29.875 1   45.46  ? 399 ALA P O   1 
ATOM   4418  C  CB  . ALA C 3 158 ? -0.814  2.335   28.723 1   49.55  ? 399 ALA P CB  1 
ATOM   4419  N  N   . SER C 3 159 ? 1.069   2.866   31.333 1   46.43  ? 400 SER P N   1 
ATOM   4420  C  CA  . SER C 3 159 ? 1.645   2.312   32.582 1   48     ? 400 SER P CA  1 
ATOM   4421  C  C   . SER C 3 159 ? 0.978   0.96    32.883 1   49.99  ? 400 SER P C   1 
ATOM   4422  O  O   . SER C 3 159 ? -0.256  0.945   33.058 1   53.03  ? 400 SER P O   1 
ATOM   4423  C  CB  . SER C 3 159 ? 1.478   3.3     33.704 1   48.44  ? 400 SER P CB  1 
ATOM   4424  O  OG  . SER C 3 159 ? 2.169   2.876   34.864 1   52.31  ? 400 SER P OG  1 
ATOM   4425  N  N   . ARG C 3 160 ? 1.762   -0.127  32.911 1   52.92  ? 401 ARG P N   1 
ATOM   4426  C  CA  . ARG C 3 160 ? 1.297   -1.536  33.087 1   52.18  ? 401 ARG P CA  1 
ATOM   4427  C  C   . ARG C 3 160 ? 1.88    -2.126  34.378 1   50.82  ? 401 ARG P C   1 
ATOM   4428  O  O   . ARG C 3 160 ? 3.057   -1.859  34.674 1   49.97  ? 401 ARG P O   1 
ATOM   4429  C  CB  . ARG C 3 160 ? 1.738   -2.413  31.911 1   53.22  ? 401 ARG P CB  1 
ATOM   4430  C  CG  . ARG C 3 160 ? 1.069   -2.091  30.583 1   55.6   ? 401 ARG P CG  1 
ATOM   4431  C  CD  . ARG C 3 160 ? -0.294  -2.74   30.482 1   61.74  ? 401 ARG P CD  1 
ATOM   4432  N  NE  . ARG C 3 160 ? -1.065  -2.219  29.361 1   64.97  ? 401 ARG P NE  1 
ATOM   4433  C  CZ  . ARG C 3 160 ? -0.914  -2.56   28.084 1   65.05  ? 401 ARG P CZ  1 
ATOM   4434  N  NH1 . ARG C 3 160 ? 0.001   -3.443  27.72  1   67.6   ? 401 ARG P NH1 1 
ATOM   4435  N  NH2 . ARG C 3 160 ? -1.686  -2.002  27.167 1   66.3   ? 401 ARG P NH2 1 
ATOM   4436  N  N   . GLN C 3 161 ? 1.077   -2.911  35.103 1   52.81  ? 402 GLN P N   1 
ATOM   4437  C  CA  . GLN C 3 161 ? 1.484   -3.695  36.302 1   55.09  ? 402 GLN P CA  1 
ATOM   4438  C  C   . GLN C 3 161 ? 2.543   -4.726  35.887 1   55.08  ? 402 GLN P C   1 
ATOM   4439  O  O   . GLN C 3 161 ? 2.279   -5.471  34.921 1   53.81  ? 402 GLN P O   1 
ATOM   4440  C  CB  . GLN C 3 161 ? 0.251   -4.376  36.903 1   57.31  ? 402 GLN P CB  1 
ATOM   4441  C  CG  . GLN C 3 161 ? 0.527   -5.176  38.171 1   59.91  ? 402 GLN P CG  1 
ATOM   4442  C  CD  . GLN C 3 161 ? -0.733  -5.648  38.86  1   62.86  ? 402 GLN P CD  1 
ATOM   4443  O  OE1 . GLN C 3 161 ? -1.853  -5.334  38.455 1   61.64  ? 402 GLN P OE1 1 
ATOM   4444  N  NE2 . GLN C 3 161 ? -0.555  -6.416  39.924 1   63.65  ? 402 GLN P NE2 1 
ATOM   4445  N  N   . GLU C 3 162 ? 3.685   -4.772  36.586 1   57.24  ? 403 GLU P N   1 
ATOM   4446  C  CA  . GLU C 3 162 ? 4.795   -5.722  36.275 1   63.21  ? 403 GLU P CA  1 
ATOM   4447  C  C   . GLU C 3 162 ? 4.647   -6.96   37.16  1   67.38  ? 403 GLU P C   1 
ATOM   4448  O  O   . GLU C 3 162 ? 3.94    -6.92   38.166 1   65.97  ? 403 GLU P O   1 
ATOM   4449  C  CB  . GLU C 3 162 ? 6.198   -5.095  36.364 1   62.35  ? 403 GLU P CB  1 
ATOM   4450  C  CG  . GLU C 3 162 ? 6.362   -3.914  37.303 1   63.2   ? 403 GLU P CG  1 
ATOM   4451  C  CD  . GLU C 3 162 ? 7.8     -3.426  37.443 1   63.94  ? 403 GLU P CD  1 
ATOM   4452  O  OE1 . GLU C 3 162 ? 8.121   -2.819  38.487 1   63.21  ? 403 GLU P OE1 1 
ATOM   4453  O  OE2 . GLU C 3 162 ? 8.606   -3.659  36.516 1   60.93  ? 403 GLU P OE2 1 
ATOM   4454  N  N   . PRO C 3 163 ? 5.272   -8.11   36.801 1   70.29  ? 404 PRO P N   1 
ATOM   4455  C  CA  . PRO C 3 163 ? 5.149   -9.331  37.597 1   73.12  ? 404 PRO P CA  1 
ATOM   4456  C  C   . PRO C 3 163 ? 5.916   -9.285  38.926 1   79.61  ? 404 PRO P C   1 
ATOM   4457  O  O   . PRO C 3 163 ? 7.03    -8.792  38.931 1   77.22  ? 404 PRO P O   1 
ATOM   4458  C  CB  . PRO C 3 163 ? 5.77    -10.434 36.723 1   71.95  ? 404 PRO P CB  1 
ATOM   4459  C  CG  . PRO C 3 163 ? 5.957   -9.806  35.355 1   71.01  ? 404 PRO P CG  1 
ATOM   4460  C  CD  . PRO C 3 163 ? 6.104   -8.323  35.606 1   69.14  ? 404 PRO P CD  1 
ATOM   4461  N  N   . SER C 3 164 ? 5.299   -9.807  39.993 1   88.6   ? 405 SER P N   1 
ATOM   4462  C  CA  . SER C 3 164 ? 5.943   -10.183 41.281 1   95.03  ? 405 SER P CA  1 
ATOM   4463  C  C   . SER C 3 164 ? 4.943   -10.94  42.163 1   101.94 ? 405 SER P C   1 
ATOM   4464  O  O   . SER C 3 164 ? 3.729   -10.657 42.063 1   99.23  ? 405 SER P O   1 
ATOM   4465  C  CB  . SER C 3 164 ? 6.492   -8.985  42.014 1   96.87  ? 405 SER P CB  1 
ATOM   4466  O  OG  . SER C 3 164 ? 5.46    -8.054  42.304 1   102.02 ? 405 SER P OG  1 
ATOM   4467  N  N   . GLN C 3 165 ? 5.447   -11.859 42.993 1   109.88 ? 406 GLN P N   1 
ATOM   4468  C  CA  . GLN C 3 165 ? 4.681   -12.528 44.081 1   110.59 ? 406 GLN P CA  1 
ATOM   4469  C  C   . GLN C 3 165 ? 4.479   -11.544 45.244 1   109.71 ? 406 GLN P C   1 
ATOM   4470  O  O   . GLN C 3 165 ? 3.49    -11.72  45.987 1   111.95 ? 406 GLN P O   1 
ATOM   4471  C  CB  . GLN C 3 165 ? 5.401   -13.793 44.557 1   112.16 ? 406 GLN P CB  1 
ATOM   4472  C  CG  . GLN C 3 165 ? 5.473   -14.891 43.504 1   110.35 ? 406 GLN P CG  1 
ATOM   4473  C  CD  . GLN C 3 165 ? 6.091   -16.163 44.022 0   113.73 ? 406 GLN P CD  1 
ATOM   4474  O  OE1 . GLN C 3 165 ? 6.832   -16.166 45.003 0   113.69 ? 406 GLN P OE1 1 
ATOM   4475  N  NE2 . GLN C 3 165 ? 5.796   -17.269 43.357 0   113.7  ? 406 GLN P NE2 1 
ATOM   4476  N  N   . GLY C 3 166 ? 5.376   -10.555 45.389 1   105.64 ? 407 GLY P N   1 
ATOM   4477  C  CA  . GLY C 3 166 ? 5.397   -9.58   46.497 1   99.23  ? 407 GLY P CA  1 
ATOM   4478  C  C   . GLY C 3 166 ? 4.488   -8.387  46.246 1   93.68  ? 407 GLY P C   1 
ATOM   4479  O  O   . GLY C 3 166 ? 3.257   -8.589  46.177 1   89.06  ? 407 GLY P O   1 
ATOM   4480  N  N   . THR C 3 167 ? 5.072   -7.187  46.122 1   88.05  ? 408 THR P N   1 
ATOM   4481  C  CA  . THR C 3 167 ? 4.36    -5.878  46.094 1   84.34  ? 408 THR P CA  1 
ATOM   4482  C  C   . THR C 3 167 ? 3.913   -5.531  44.669 1   79.08  ? 408 THR P C   1 
ATOM   4483  O  O   . THR C 3 167 ? 4.621   -5.908  43.712 1   79.35  ? 408 THR P O   1 
ATOM   4484  C  CB  . THR C 3 167 ? 5.238   -4.747  46.644 1   84.64  ? 408 THR P CB  1 
ATOM   4485  O  OG1 . THR C 3 167 ? 6.432   -4.683  45.861 1   81.92  ? 408 THR P OG1 1 
ATOM   4486  C  CG2 . THR C 3 167 ? 5.58    -4.925  48.108 1   84.89  ? 408 THR P CG2 1 
ATOM   4487  N  N   . THR C 3 168 ? 2.792   -4.814  44.547 1   71.14  ? 409 THR P N   1 
ATOM   4488  C  CA  . THR C 3 168 ? 2.258   -4.289  43.264 1   67.55  ? 409 THR P CA  1 
ATOM   4489  C  C   . THR C 3 168 ? 3.065   -3.048  42.87  1   63.37  ? 409 THR P C   1 
ATOM   4490  O  O   . THR C 3 168 ? 2.922   -2.007  43.547 1   66.23  ? 409 THR P O   1 
ATOM   4491  C  CB  . THR C 3 168 ? 0.758   -3.982  43.361 1   69.85  ? 409 THR P CB  1 
ATOM   4492  O  OG1 . THR C 3 168 ? 0.112   -5.125  43.921 1   71.56  ? 409 THR P OG1 1 
ATOM   4493  C  CG2 . THR C 3 168 ? 0.135   -3.648  42.021 1   70.51  ? 409 THR P CG2 1 
ATOM   4494  N  N   . THR C 3 169 ? 3.903   -3.171  41.838 1   58.99  ? 410 THR P N   1 
ATOM   4495  C  CA  . THR C 3 169 ? 4.602   -2.044  41.165 1   54.93  ? 410 THR P CA  1 
ATOM   4496  C  C   . THR C 3 169 ? 4.209   -2.009  39.687 1   53.09  ? 410 THR P C   1 
ATOM   4497  O  O   . THR C 3 169 ? 3.771   -3.044  39.151 1   52.44  ? 410 THR P O   1 
ATOM   4498  C  CB  . THR C 3 169 ? 6.126   -2.135  41.284 1   54.46  ? 410 THR P CB  1 
ATOM   4499  O  OG1 . THR C 3 169 ? 6.569   -3.321  40.627 1   55.29  ? 410 THR P OG1 1 
ATOM   4500  C  CG2 . THR C 3 169 ? 6.623   -2.116  42.713 1   54.64  ? 410 THR P CG2 1 
ATOM   4501  N  N   . PHE C 3 170 ? 4.368   -0.839  39.071 1   53.26  ? 411 PHE P N   1 
ATOM   4502  C  CA  . PHE C 3 170 ? 4.061   -0.565  37.647 1   49.86  ? 411 PHE P CA  1 
ATOM   4503  C  C   . PHE C 3 170 ? 5.348   -0.145  36.934 1   47.51  ? 411 PHE P C   1 
ATOM   4504  O  O   . PHE C 3 170 ? 6.313   0.306   37.586 1   46.36  ? 411 PHE P O   1 
ATOM   4505  C  CB  . PHE C 3 170 ? 2.96    0.489   37.548 1   50.7   ? 411 PHE P CB  1 
ATOM   4506  C  CG  . PHE C 3 170 ? 1.62    0.02    38.059 1   53.85  ? 411 PHE P CG  1 
ATOM   4507  C  CD1 . PHE C 3 170 ? 1.339   0.008   39.421 1   55.11  ? 411 PHE P CD1 1 
ATOM   4508  C  CD2 . PHE C 3 170 ? 0.635   -0.411  37.183 1   52.47  ? 411 PHE P CD2 1 
ATOM   4509  C  CE1 . PHE C 3 170 ? 0.105   -0.423  39.892 1   52.98  ? 411 PHE P CE1 1 
ATOM   4510  C  CE2 . PHE C 3 170 ? -0.598  -0.841  37.657 1   53.55  ? 411 PHE P CE2 1 
ATOM   4511  C  CZ  . PHE C 3 170 ? -0.861  -0.847  39.009 1   52.32  ? 411 PHE P CZ  1 
ATOM   4512  N  N   . ALA C 3 171 ? 5.36    -0.336  35.618 1   45.72  ? 412 ALA P N   1 
ATOM   4513  C  CA  . ALA C 3 171 ? 6.42    0.118   34.695 1   44.07  ? 412 ALA P CA  1 
ATOM   4514  C  C   . ALA C 3 171 ? 5.764   0.853   33.524 1   43.62  ? 412 ALA P C   1 
ATOM   4515  O  O   . ALA C 3 171 ? 4.605   0.524   33.19  1   44.16  ? 412 ALA P O   1 
ATOM   4516  C  CB  . ALA C 3 171 ? 7.227   -1.065  34.222 1   44.88  ? 412 ALA P CB  1 
ATOM   4517  N  N   . VAL C 3 172 ? 6.484   1.809   32.932 1   39.83  ? 413 VAL P N   1 
ATOM   4518  C  CA  . VAL C 3 172 ? 6.104   2.494   31.664 1   38.11  ? 413 VAL P CA  1 
ATOM   4519  C  C   . VAL C 3 172 ? 7.381   2.639   30.832 1   38.63  ? 413 VAL P C   1 
ATOM   4520  O  O   . VAL C 3 172 ? 8.471   2.711   31.439 1   39.47  ? 413 VAL P O   1 
ATOM   4521  C  CB  . VAL C 3 172 ? 5.406   3.841   31.95  1   38.59  ? 413 VAL P CB  1 
ATOM   4522  C  CG1 . VAL C 3 172 ? 6.319   4.854   32.621 1   39.12  ? 413 VAL P CG1 1 
ATOM   4523  C  CG2 . VAL C 3 172 ? 4.776   4.442   30.71  1   39.21  ? 413 VAL P CG2 1 
ATOM   4524  N  N   . THR C 3 173 ? 7.261   2.637   29.503 1   37.73  ? 414 THR P N   1 
ATOM   4525  C  CA  . THR C 3 173 ? 8.39    2.879   28.565 1   37.98  ? 414 THR P CA  1 
ATOM   4526  C  C   . THR C 3 173 ? 8.054   4.077   27.675 1   38.33  ? 414 THR P C   1 
ATOM   4527  O  O   . THR C 3 173 ? 6.86    4.329   27.432 1   38.71  ? 414 THR P O   1 
ATOM   4528  C  CB  . THR C 3 173 ? 8.738   1.633   27.741 1   36.68  ? 414 THR P CB  1 
ATOM   4529  O  OG1 . THR C 3 173 ? 7.544   1.145   27.13  1   37.11  ? 414 THR P OG1 1 
ATOM   4530  C  CG2 . THR C 3 173 ? 9.377   0.548   28.58  1   35.88  ? 414 THR P CG2 1 
ATOM   4531  N  N   . SER C 3 174 ? 9.087   4.787   27.226 1   38.32  ? 415 SER P N   1 
ATOM   4532  C  CA  . SER C 3 174 ? 8.997   5.897   26.247 1   38.15  ? 415 SER P CA  1 
ATOM   4533  C  C   . SER C 3 174 ? 10.205  5.841   25.316 1   37.65  ? 415 SER P C   1 
ATOM   4534  O  O   . SER C 3 174 ? 11.295  5.458   25.782 1   36.45  ? 415 SER P O   1 
ATOM   4535  C  CB  . SER C 3 174 ? 8.901   7.226   26.935 1   38.99  ? 415 SER P CB  1 
ATOM   4536  O  OG  . SER C 3 174 ? 8.344   8.199   26.067 1   38.52  ? 415 SER P OG  1 
ATOM   4537  N  N   . ILE C 3 175 ? 9.999   6.243   24.064 1   39.82  ? 416 ILE P N   1 
ATOM   4538  C  CA  . ILE C 3 175 ? 10.946  6.052   22.927 1   41     ? 416 ILE P CA  1 
ATOM   4539  C  C   . ILE C 3 175 ? 10.986  7.363   22.127 1   41.52  ? 416 ILE P C   1 
ATOM   4540  O  O   . ILE C 3 175 ? 9.916   7.796   21.646 1   40.56  ? 416 ILE P O   1 
ATOM   4541  C  CB  . ILE C 3 175 ? 10.508  4.804   22.123 1   42     ? 416 ILE P CB  1 
ATOM   4542  C  CG1 . ILE C 3 175 ? 11.1    3.531   22.734 1   41.4   ? 416 ILE P CG1 1 
ATOM   4543  C  CG2 . ILE C 3 175 ? 10.836  4.887   20.642 1   44.17  ? 416 ILE P CG2 1 
ATOM   4544  C  CD1 . ILE C 3 175 ? 12.41   3.132   22.37  0   40.78  ? 416 ILE P CD1 1 
ATOM   4545  N  N   . LEU C 3 176 ? 12.166  7.988   22.044 1   43.01  ? 417 LEU P N   1 
ATOM   4546  C  CA  . LEU C 3 176 ? 12.437  9.234   21.272 1   43.56  ? 417 LEU P CA  1 
ATOM   4547  C  C   . LEU C 3 176 ? 13.421  8.906   20.141 1   44.6   ? 417 LEU P C   1 
ATOM   4548  O  O   . LEU C 3 176 ? 14.557  8.485   20.465 1   41.85  ? 417 LEU P O   1 
ATOM   4549  C  CB  . LEU C 3 176 ? 13.007  10.302  22.218 1   43     ? 417 LEU P CB  1 
ATOM   4550  C  CG  . LEU C 3 176 ? 13.586  11.557  21.555 1   42.18  ? 417 LEU P CG  1 
ATOM   4551  C  CD1 . LEU C 3 176 ? 12.539  12.308  20.748 1   41.18  ? 417 LEU P CD1 1 
ATOM   4552  C  CD2 . LEU C 3 176 ? 14.216  12.472  22.588 1   41.76  ? 417 LEU P CD2 1 
ATOM   4553  N  N   . ARG C 3 177 ? 12.998  9.084   18.88  1   46.16  ? 418 ARG P N   1 
ATOM   4554  C  CA  . ARG C 3 177 ? 13.874  8.956   17.683 1   49.35  ? 418 ARG P CA  1 
ATOM   4555  C  C   . ARG C 3 177 ? 14.585  10.3    17.465 1   50.65  ? 418 ARG P C   1 
ATOM   4556  O  O   . ARG C 3 177 ? 13.899  11.346  17.467 1   49.9   ? 418 ARG P O   1 
ATOM   4557  C  CB  . ARG C 3 177 ? 13.114  8.598   16.398 1   51.44  ? 418 ARG P CB  1 
ATOM   4558  C  CG  . ARG C 3 177 ? 12.083  7.482   16.504 1   52.23  ? 418 ARG P CG  1 
ATOM   4559  C  CD  . ARG C 3 177 ? 12.608  6.08    16.742 1   51.35  ? 418 ARG P CD  1 
ATOM   4560  N  NE  . ARG C 3 177 ? 13.721  5.637   15.906 1   52.39  ? 418 ARG P NE  1 
ATOM   4561  C  CZ  . ARG C 3 177 ? 13.681  5.391   14.593 1   51.69  ? 418 ARG P CZ  1 
ATOM   4562  N  NH1 . ARG C 3 177 ? 12.574  5.577   13.89  1   51.55  ? 418 ARG P NH1 1 
ATOM   4563  N  NH2 . ARG C 3 177 ? 14.778  4.974   13.98  1   50.64  ? 418 ARG P NH2 1 
ATOM   4564  N  N   . VAL C 3 178 ? 15.906  10.275  17.291 1   51.05  ? 419 VAL P N   1 
ATOM   4565  C  CA  . VAL C 3 178 ? 16.736  11.488  17.029 1   51.92  ? 419 VAL P CA  1 
ATOM   4566  C  C   . VAL C 3 178 ? 17.685  11.181  15.871 1   52.15  ? 419 VAL P C   1 
ATOM   4567  O  O   . VAL C 3 178 ? 18.034  10.002  15.693 1   52.08  ? 419 VAL P O   1 
ATOM   4568  C  CB  . VAL C 3 178 ? 17.495  11.936  18.293 1   51.04  ? 419 VAL P CB  1 
ATOM   4569  C  CG1 . VAL C 3 178 ? 16.541  12.14   19.457 1   52.58  ? 419 VAL P CG1 1 
ATOM   4570  C  CG2 . VAL C 3 178 ? 18.603  10.973  18.689 1   51.69  ? 419 VAL P CG2 1 
ATOM   4571  N  N   . ALA C 3 179 ? 18.082  12.213  15.126 1   54.85  ? 420 ALA P N   1 
ATOM   4572  C  CA  . ALA C 3 179 ? 19.097  12.133  14.05  1   56.17  ? 420 ALA P CA  1 
ATOM   4573  C  C   . ALA C 3 179 ? 20.42   11.657  14.658 1   57     ? 420 ALA P C   1 
ATOM   4574  O  O   . ALA C 3 179 ? 20.786  12.159  15.746 1   55.35  ? 420 ALA P O   1 
ATOM   4575  C  CB  . ALA C 3 179 ? 19.249  13.472  13.373 1   57.36  ? 420 ALA P CB  1 
ATOM   4576  N  N   . ALA C 3 180 ? 21.085  10.703  13.997 1   58.46  ? 421 ALA P N   1 
ATOM   4577  C  CA  . ALA C 3 180 ? 22.431  10.194  14.354 1   59.03  ? 421 ALA P CA  1 
ATOM   4578  C  C   . ALA C 3 180 ? 23.425  11.362  14.409 1   60.31  ? 421 ALA P C   1 
ATOM   4579  O  O   . ALA C 3 180 ? 24.325  11.317  15.269 1   60.82  ? 421 ALA P O   1 
ATOM   4580  C  CB  . ALA C 3 180 ? 22.873  9.14    13.366 1   59.84  ? 421 ALA P CB  1 
ATOM   4581  N  N   . GLU C 3 181 ? 23.257  12.358  13.527 1   62.67  ? 422 GLU P N   1 
ATOM   4582  C  CA  . GLU C 3 181 ? 24.025  13.636  13.514 1   67.43  ? 422 GLU P CA  1 
ATOM   4583  C  C   . GLU C 3 181 ? 24.02   14.254  14.919 1   64.16  ? 422 GLU P C   1 
ATOM   4584  O  O   . GLU C 3 181 ? 25.116  14.389  15.506 1   61.48  ? 422 GLU P O   1 
ATOM   4585  C  CB  . GLU C 3 181 ? 23.43   14.625  12.509 1   75.46  ? 422 GLU P CB  1 
ATOM   4586  C  CG  . GLU C 3 181 ? 23.687  14.264  11.057 1   82.55  ? 422 GLU P CG  1 
ATOM   4587  C  CD  . GLU C 3 181 ? 23.065  15.224  10.055 1   86.88  ? 422 GLU P CD  1 
ATOM   4588  O  OE1 . GLU C 3 181 ? 23.274  16.449  10.198 1   86.59  ? 422 GLU P OE1 1 
ATOM   4589  O  OE2 . GLU C 3 181 ? 22.368  14.745  9.137  1   91.89  ? 422 GLU P OE2 1 
ATOM   4590  N  N   . ASP C 3 182 ? 22.829  14.58   15.437 1   59.12  ? 423 ASP P N   1 
ATOM   4591  C  CA  . ASP C 3 182 ? 22.621  15.226  16.763 1   57.37  ? 423 ASP P CA  1 
ATOM   4592  C  C   . ASP C 3 182 ? 23.304  14.392  17.853 1   57.53  ? 423 ASP P C   1 
ATOM   4593  O  O   . ASP C 3 182 ? 23.979  14.993  18.711 1   57.81  ? 423 ASP P O   1 
ATOM   4594  C  CB  . ASP C 3 182 ? 21.135  15.395  17.102 1   56.65  ? 423 ASP P CB  1 
ATOM   4595  C  CG  . ASP C 3 182 ? 20.362  16.322  16.177 1   56.25  ? 423 ASP P CG  1 
ATOM   4596  O  OD1 . ASP C 3 182 ? 20.99   16.955  15.301 1   58.41  ? 423 ASP P OD1 1 
ATOM   4597  O  OD2 . ASP C 3 182 ? 19.132  16.396  16.335 1   52.92  ? 423 ASP P OD2 1 
ATOM   4598  N  N   . TRP C 3 183 ? 23.138  13.065  17.817 1   57.25  ? 424 TRP P N   1 
ATOM   4599  C  CA  . TRP C 3 183 ? 23.745  12.124  18.798 1   58.45  ? 424 TRP P CA  1 
ATOM   4600  C  C   . TRP C 3 183 ? 25.277  12.186  18.72  1   59.22  ? 424 TRP P C   1 
ATOM   4601  O  O   . TRP C 3 183 ? 25.92   12.095  19.786 1   58.01  ? 424 TRP P O   1 
ATOM   4602  C  CB  . TRP C 3 183 ? 23.232  10.692  18.592 1   57.21  ? 424 TRP P CB  1 
ATOM   4603  C  CG  . TRP C 3 183 ? 23.849  9.718   19.548 1   54.43  ? 424 TRP P CG  1 
ATOM   4604  C  CD1 . TRP C 3 183 ? 24.909  8.894   19.31  1   54.68  ? 424 TRP P CD1 1 
ATOM   4605  C  CD2 . TRP C 3 183 ? 23.493  9.522   20.926 1   53.67  ? 424 TRP P CD2 1 
ATOM   4606  N  NE1 . TRP C 3 183 ? 25.217  8.178   20.436 1   55.5   ? 424 TRP P NE1 1 
ATOM   4607  C  CE2 . TRP C 3 183 ? 24.367  8.542   21.444 1   53.37  ? 424 TRP P CE2 1 
ATOM   4608  C  CE3 . TRP C 3 183 ? 22.517  10.067  21.769 1   52.71  ? 424 TRP P CE3 1 
ATOM   4609  C  CZ2 . TRP C 3 183 ? 24.287  8.097   22.763 1   53.52  ? 424 TRP P CZ2 1 
ATOM   4610  C  CZ3 . TRP C 3 183 ? 22.441  9.629   23.073 1   51.73  ? 424 TRP P CZ3 1 
ATOM   4611  C  CH2 . TRP C 3 183 ? 23.313  8.655   23.561 1   52.54  ? 424 TRP P CH2 1 
ATOM   4612  N  N   . LYS C 3 184 ? 25.833  12.333  17.513 1   65.84  ? 425 LYS P N   1 
ATOM   4613  C  CA  . LYS C 3 184 ? 27.302  12.291  17.251 1   73.1   ? 425 LYS P CA  1 
ATOM   4614  C  C   . LYS C 3 184 ? 27.934  13.682  17.451 1   71.31  ? 425 LYS P C   1 
ATOM   4615  O  O   . LYS C 3 184 ? 29.147  13.716  17.737 1   73.38  ? 425 LYS P O   1 
ATOM   4616  C  CB  . LYS C 3 184 ? 27.577  11.679  15.872 1   77.34  ? 425 LYS P CB  1 
ATOM   4617  C  CG  . LYS C 3 184 ? 27.361  10.17   15.808 1   80.45  ? 425 LYS P CG  1 
ATOM   4618  C  CD  . LYS C 3 184 ? 27.425  9.575   14.414 1   83.78  ? 425 LYS P CD  1 
ATOM   4619  C  CE  . LYS C 3 184 ? 27.397  8.06    14.415 1   86.67  ? 425 LYS P CE  1 
ATOM   4620  N  NZ  . LYS C 3 184 ? 26.048  7.492   14.654 0   84.06  ? 425 LYS P NZ  1 
ATOM   4621  N  N   . LYS C 3 185 ? 27.159  14.776  17.35  1   68.42  ? 426 LYS P N   1 
ATOM   4622  C  CA  . LYS C 3 185 ? 27.562  16.143  17.803 1   65.18  ? 426 LYS P CA  1 
ATOM   4623  C  C   . LYS C 3 185 ? 27.817  16.16   19.317 1   61.59  ? 426 LYS P C   1 
ATOM   4624  O  O   . LYS C 3 185 ? 28.506  17.093  19.78  1   65.71  ? 426 LYS P O   1 
ATOM   4625  C  CB  . LYS C 3 185 ? 26.471  17.191  17.556 1   69.73  ? 426 LYS P CB  1 
ATOM   4626  C  CG  . LYS C 3 185 ? 26.209  17.589  16.113 1   73.61  ? 426 LYS P CG  1 
ATOM   4627  C  CD  . LYS C 3 185 ? 25.024  18.535  15.991 1   77.23  ? 426 LYS P CD  1 
ATOM   4628  C  CE  . LYS C 3 185 ? 24.348  18.492  14.636 1   81.62  ? 426 LYS P CE  1 
ATOM   4629  N  NZ  . LYS C 3 185 ? 23.084  19.266  14.632 1   83.55  ? 426 LYS P NZ  1 
ATOM   4630  N  N   . GLY C 3 186 ? 27.223  15.222  20.064 1   55.61  ? 427 GLY P N   1 
ATOM   4631  C  CA  . GLY C 3 186 ? 27.326  15.121  21.533 1   52.29  ? 427 GLY P CA  1 
ATOM   4632  C  C   . GLY C 3 186 ? 26.205  15.866  22.242 1   48.59  ? 427 GLY P C   1 
ATOM   4633  O  O   . GLY C 3 186 ? 26.394  16.226  23.417 1   46.9   ? 427 GLY P O   1 
ATOM   4634  N  N   . ASP C 3 187 ? 25.068  16.074  21.57  1   45.8   ? 428 ASP P N   1 
ATOM   4635  C  CA  . ASP C 3 187 ? 23.853  16.686  22.166 1   46.43  ? 428 ASP P CA  1 
ATOM   4636  C  C   . ASP C 3 187 ? 23.39   15.842  23.357 1   46.36  ? 428 ASP P C   1 
ATOM   4637  O  O   . ASP C 3 187 ? 23.552  14.605  23.319 1   47.75  ? 428 ASP P O   1 
ATOM   4638  C  CB  . ASP C 3 187 ? 22.714  16.812  21.149 1   46     ? 428 ASP P CB  1 
ATOM   4639  C  CG  . ASP C 3 187 ? 22.916  17.906  20.114 1   46.41  ? 428 ASP P CG  1 
ATOM   4640  O  OD1 . ASP C 3 187 ? 24.043  18.462  20.047 1   49.56  ? 428 ASP P OD1 1 
ATOM   4641  O  OD2 . ASP C 3 187 ? 21.943  18.204  19.387 1   43.12  ? 428 ASP P OD2 1 
ATOM   4642  N  N   . THR C 3 188 ? 22.829  16.491  24.375 1   44.68  ? 429 THR P N   1 
ATOM   4643  C  CA  . THR C 3 188 ? 22.231  15.814  25.549 1   44.44  ? 429 THR P CA  1 
ATOM   4644  C  C   . THR C 3 188 ? 20.801  15.421  25.18  1   44.36  ? 429 THR P C   1 
ATOM   4645  O  O   . THR C 3 188 ? 20.187  16.094  24.326 1   43.59  ? 429 THR P O   1 
ATOM   4646  C  CB  . THR C 3 188 ? 22.309  16.672  26.818 1   45.68  ? 429 THR P CB  1 
ATOM   4647  O  OG1 . THR C 3 188 ? 21.611  17.898  26.599 1   46.35  ? 429 THR P OG1 1 
ATOM   4648  C  CG2 . THR C 3 188 ? 23.737  16.947  27.239 1   45.17  ? 429 THR P CG2 1 
ATOM   4649  N  N   . PHE C 3 189 ? 20.334  14.315  25.753 1   43.82  ? 430 PHE P N   1 
ATOM   4650  C  CA  . PHE C 3 189 ? 18.929  13.85   25.691 1   42.51  ? 430 PHE P CA  1 
ATOM   4651  C  C   . PHE C 3 189 ? 18.536  13.451  27.108 1   40.84  ? 430 PHE P C   1 
ATOM   4652  O  O   . PHE C 3 189 ? 19.343  12.788  27.771 1   38.96  ? 430 PHE P O   1 
ATOM   4653  C  CB  . PHE C 3 189 ? 18.794  12.732  24.66  1   43.82  ? 430 PHE P CB  1 
ATOM   4654  C  CG  . PHE C 3 189 ? 19.195  13.151  23.268 1   44.41  ? 430 PHE P CG  1 
ATOM   4655  C  CD1 . PHE C 3 189 ? 18.268  13.717  22.402 1   43.86  ? 430 PHE P CD1 1 
ATOM   4656  C  CD2 . PHE C 3 189 ? 20.504  13.002  22.831 1   44.84  ? 430 PHE P CD2 1 
ATOM   4657  C  CE1 . PHE C 3 189 ? 18.641  14.115  21.126 1   44.26  ? 430 PHE P CE1 1 
ATOM   4658  C  CE2 . PHE C 3 189 ? 20.875  13.403  21.553 1   45.21  ? 430 PHE P CE2 1 
ATOM   4659  C  CZ  . PHE C 3 189 ? 19.942  13.957  20.702 1   44.01  ? 430 PHE P CZ  1 
ATOM   4660  N  N   . SER C 3 190 ? 17.385  13.929  27.575 1   42.29  ? 431 SER P N   1 
ATOM   4661  C  CA  . SER C 3 190 ? 16.878  13.706  28.953 1   44.64  ? 431 SER P CA  1 
ATOM   4662  C  C   . SER C 3 190 ? 15.46   13.139  28.877 1   45.08  ? 431 SER P C   1 
ATOM   4663  O  O   . SER C 3 190 ? 14.681  13.608  28.024 1   43.13  ? 431 SER P O   1 
ATOM   4664  C  CB  . SER C 3 190 ? 16.91   14.976  29.777 1   45.55  ? 431 SER P CB  1 
ATOM   4665  O  OG  . SER C 3 190 ? 18.144  15.667  29.631 1   47.07  ? 431 SER P OG  1 
ATOM   4666  N  N   . CYS C 3 191 ? 15.144  12.161  29.725 1   46.52  ? 432 CYS P N   1 
ATOM   4667  C  CA  . CYS C 3 191 ? 13.745  11.761  30.019 1   49.32  ? 432 CYS P CA  1 
ATOM   4668  C  C   . CYS C 3 191 ? 13.447  12.163  31.471 1   49.01  ? 432 CYS P C   1 
ATOM   4669  O  O   . CYS C 3 191 ? 14.284  11.88   32.356 1   49.6   ? 432 CYS P O   1 
ATOM   4670  C  CB  . CYS C 3 191 ? 13.494  10.294  29.671 1   51.93  ? 432 CYS P CB  1 
ATOM   4671  S  SG  . CYS C 3 191 ? 13.7    9.114   31.027 1   57.4   ? 432 CYS P SG  1 
ATOM   4672  N  N   . MET C 3 192 ? 12.344  12.889  31.671 1   48.63  ? 433 MET P N   1 
ATOM   4673  C  CA  . MET C 3 192 ? 11.854  13.382  32.983 1   49.07  ? 433 MET P CA  1 
ATOM   4674  C  C   . MET C 3 192 ? 10.577  12.618  33.336 1   47     ? 433 MET P C   1 
ATOM   4675  O  O   . MET C 3 192 ? 9.633   12.641  32.524 1   47     ? 433 MET P O   1 
ATOM   4676  C  CB  . MET C 3 192 ? 11.54   14.877  32.925 1   51.74  ? 433 MET P CB  1 
ATOM   4677  C  CG  . MET C 3 192 ? 12.765  15.733  32.712 1   55.71  ? 433 MET P CG  1 
ATOM   4678  S  SD  . MET C 3 192 ? 12.371  17.492  32.738 1   57.48  ? 433 MET P SD  1 
ATOM   4679  C  CE  . MET C 3 192 ? 11.456  17.632  31.203 1   59.17  ? 433 MET P CE  1 
ATOM   4680  N  N   . VAL C 3 193 ? 10.563  11.962  34.495 1   43.39  ? 434 VAL P N   1 
ATOM   4681  C  CA  . VAL C 3 193 ? 9.444   11.089  34.948 1   43.94  ? 434 VAL P CA  1 
ATOM   4682  C  C   . VAL C 3 193 ? 8.781   11.769  36.146 1   43.55  ? 434 VAL P C   1 
ATOM   4683  O  O   . VAL C 3 193 ? 9.449   11.882  37.191 1   42.31  ? 434 VAL P O   1 
ATOM   4684  C  CB  . VAL C 3 193 ? 9.952   9.674   35.284 1   44.2   ? 434 VAL P CB  1 
ATOM   4685  C  CG1 . VAL C 3 193 ? 8.856   8.791   35.865 1   43.41  ? 434 VAL P CG1 1 
ATOM   4686  C  CG2 . VAL C 3 193 ? 10.584  9.013   34.065 1   43.73  ? 434 VAL P CG2 1 
ATOM   4687  N  N   . GLY C 3 194 ? 7.534   12.217  35.976 1   44.08  ? 435 GLY P N   1 
ATOM   4688  C  CA  . GLY C 3 194 ? 6.714   12.84   37.034 1   46.79  ? 435 GLY P CA  1 
ATOM   4689  C  C   . GLY C 3 194 ? 5.938   11.787  37.802 1   48.76  ? 435 GLY P C   1 
ATOM   4690  O  O   . GLY C 3 194 ? 5.304   10.932  37.146 1   50.1   ? 435 GLY P O   1 
ATOM   4691  N  N   . HIS C 3 195 ? 5.984   11.824  39.137 1   49.47  ? 436 HIS P N   1 
ATOM   4692  C  CA  . HIS C 3 195 ? 5.329   10.804  39.998 1   50.92  ? 436 HIS P CA  1 
ATOM   4693  C  C   . HIS C 3 195 ? 5.169   11.288  41.446 1   52     ? 436 HIS P C   1 
ATOM   4694  O  O   . HIS C 3 195 ? 6.107   11.91   41.97  1   51.96  ? 436 HIS P O   1 
ATOM   4695  C  CB  . HIS C 3 195 ? 6.11    9.492   39.913 1   50.89  ? 436 HIS P CB  1 
ATOM   4696  C  CG  . HIS C 3 195 ? 5.413   8.381   40.61  1   50.19  ? 436 HIS P CG  1 
ATOM   4697  N  ND1 . HIS C 3 195 ? 4.317   7.756   40.069 1   49.14  ? 436 HIS P ND1 1 
ATOM   4698  C  CD2 . HIS C 3 195 ? 5.628   7.816   41.813 1   49.78  ? 436 HIS P CD2 1 
ATOM   4699  C  CE1 . HIS C 3 195 ? 3.891   6.841   40.906 1   49.49  ? 436 HIS P CE1 1 
ATOM   4700  N  NE2 . HIS C 3 195 ? 4.68    6.853   41.985 1   49.81  ? 436 HIS P NE2 1 
ATOM   4701  N  N   . GLU C 3 196 ? 4.031   10.937  42.063 1   53.91  ? 437 GLU P N   1 
ATOM   4702  C  CA  . GLU C 3 196 ? 3.551   11.403  43.401 1   54.32  ? 437 GLU P CA  1 
ATOM   4703  C  C   . GLU C 3 196 ? 4.578   11.092  44.498 1   52.66  ? 437 GLU P C   1 
ATOM   4704  O  O   . GLU C 3 196 ? 4.72    11.911  45.414 1   56.06  ? 437 GLU P O   1 
ATOM   4705  C  CB  . GLU C 3 196 ? 2.25    10.724  43.856 1   57.15  ? 437 GLU P CB  1 
ATOM   4706  C  CG  . GLU C 3 196 ? 1.35    10.19   42.752 1   60.77  ? 437 GLU P CG  1 
ATOM   4707  C  CD  . GLU C 3 196 ? -0.007  9.697   43.224 1   61.09  ? 437 GLU P CD  1 
ATOM   4708  O  OE1 . GLU C 3 196 ? -0.911  9.596   42.376 1   62.15  ? 437 GLU P OE1 1 
ATOM   4709  O  OE2 . GLU C 3 196 ? -0.153  9.407   44.433 1   60.7   ? 437 GLU P OE2 1 
ATOM   4710  N  N   . ALA C 3 197 ? 5.216   9.922   44.429 1   53.75  ? 438 ALA P N   1 
ATOM   4711  C  CA  . ALA C 3 197 ? 6.16    9.395   45.444 1   54.79  ? 438 ALA P CA  1 
ATOM   4712  C  C   . ALA C 3 197 ? 7.542   10.051  45.327 1   55.34  ? 438 ALA P C   1 
ATOM   4713  O  O   . ALA C 3 197 ? 8.355   9.818   46.24  1   57.17  ? 438 ALA P O   1 
ATOM   4714  C  CB  . ALA C 3 197 ? 6.27    7.893   45.33  1   54.26  ? 438 ALA P CB  1 
ATOM   4715  N  N   . LEU C 3 198 ? 7.817   10.826  44.27  1   56.61  ? 439 LEU P N   1 
ATOM   4716  C  CA  . LEU C 3 198 ? 9.116   11.537  44.103 1   58.42  ? 439 LEU P CA  1 
ATOM   4717  C  C   . LEU C 3 198 ? 9.131   12.792  44.974 1   61.81  ? 439 LEU P C   1 
ATOM   4718  O  O   . LEU C 3 198 ? 8.301   13.678  44.777 1   61.19  ? 439 LEU P O   1 
ATOM   4719  C  CB  . LEU C 3 198 ? 9.34    11.891  42.629 1   56.96  ? 439 LEU P CB  1 
ATOM   4720  C  CG  . LEU C 3 198 ? 9.567   10.704  41.696 1   54.24  ? 439 LEU P CG  1 
ATOM   4721  C  CD1 . LEU C 3 198 ? 9.598   11.16   40.247 1   52.36  ? 439 LEU P CD1 1 
ATOM   4722  C  CD2 . LEU C 3 198 ? 10.849  9.964   42.053 1   53     ? 439 LEU P CD2 1 
ATOM   4723  N  N   . PRO C 3 199 ? 10.086  12.928  45.93  1   65.18  ? 440 PRO P N   1 
ATOM   4724  C  CA  . PRO C 3 199 ? 10.141  14.106  46.802 1   66.98  ? 440 PRO P CA  1 
ATOM   4725  C  C   . PRO C 3 199 ? 10.459  15.421  46.069 1   68.05  ? 440 PRO P C   1 
ATOM   4726  O  O   . PRO C 3 199 ? 10.156  16.465  46.614 1   71.41  ? 440 PRO P O   1 
ATOM   4727  C  CB  . PRO C 3 199 ? 11.257  13.772  47.808 1   67.45  ? 440 PRO P CB  1 
ATOM   4728  C  CG  . PRO C 3 199 ? 12.128  12.765  47.093 1   65.78  ? 440 PRO P CG  1 
ATOM   4729  C  CD  . PRO C 3 199 ? 11.178  11.98   46.213 1   65.76  ? 440 PRO P CD  1 
ATOM   4730  N  N   . LEU C 3 200 ? 11.059  15.339  44.876 1   69.22  ? 441 LEU P N   1 
ATOM   4731  C  CA  . LEU C 3 200 ? 11.323  16.495  43.976 1   68.03  ? 441 LEU P CA  1 
ATOM   4732  C  C   . LEU C 3 200 ? 10.356  16.468  42.781 1   65.13  ? 441 LEU P C   1 
ATOM   4733  O  O   . LEU C 3 200 ? 10.722  17.042  41.736 1   66.71  ? 441 LEU P O   1 
ATOM   4734  C  CB  . LEU C 3 200 ? 12.779  16.432  43.497 1   70.61  ? 441 LEU P CB  1 
ATOM   4735  C  CG  . LEU C 3 200 ? 13.838  16.199  44.574 1   72.41  ? 441 LEU P CG  1 
ATOM   4736  C  CD1 . LEU C 3 200 ? 15.204  15.99   43.935 1   72.82  ? 441 LEU P CD1 1 
ATOM   4737  C  CD2 . LEU C 3 200 ? 13.878  17.351  45.57  1   71.76  ? 441 LEU P CD2 1 
ATOM   4738  N  N   . ALA C 3 201 ? 9.188   15.82   42.909 1   60.19  ? 442 ALA P N   1 
ATOM   4739  C  CA  . ALA C 3 201 ? 8.074   15.805  41.924 1   58.61  ? 442 ALA P CA  1 
ATOM   4740  C  C   . ALA C 3 201 ? 8.447   15.024  40.657 1   55.67  ? 442 ALA P C   1 
ATOM   4741  O  O   . ALA C 3 201 ? 7.627   14.182  40.231 1   55.09  ? 442 ALA P O   1 
ATOM   4742  C  CB  . ALA C 3 201 ? 7.639   17.212  41.581 1   58.76  ? 442 ALA P CB  1 
ATOM   4743  N  N   . PHE C 3 202 ? 9.589   15.342  40.037 1   52.26  ? 443 PHE P N   1 
ATOM   4744  C  CA  . PHE C 3 202 ? 10.138  14.657  38.837 1   50.98  ? 443 PHE P CA  1 
ATOM   4745  C  C   . PHE C 3 202 ? 11.522  14.069  39.144 1   51.83  ? 443 PHE P C   1 
ATOM   4746  O  O   . PHE C 3 202 ? 12.189  14.512  40.095 1   54.95  ? 443 PHE P O   1 
ATOM   4747  C  CB  . PHE C 3 202 ? 10.206  15.627  37.658 1   49.03  ? 443 PHE P CB  1 
ATOM   4748  C  CG  . PHE C 3 202 ? 8.873   15.943  37.029 1   46.99  ? 443 PHE P CG  1 
ATOM   4749  C  CD1 . PHE C 3 202 ? 7.978   16.798  37.654 1   46.55  ? 443 PHE P CD1 1 
ATOM   4750  C  CD2 . PHE C 3 202 ? 8.517   15.393  35.806 1   45.92  ? 443 PHE P CD2 1 
ATOM   4751  C  CE1 . PHE C 3 202 ? 6.754   17.092  37.074 1   46.02  ? 443 PHE P CE1 1 
ATOM   4752  C  CE2 . PHE C 3 202 ? 7.293   15.691  35.225 1   46.34  ? 443 PHE P CE2 1 
ATOM   4753  C  CZ  . PHE C 3 202 ? 6.413   16.539  35.861 1   46.03  ? 443 PHE P CZ  1 
ATOM   4754  N  N   . THR C 3 203 ? 11.909  13.053  38.371 1   52.8   ? 444 THR P N   1 
ATOM   4755  C  CA  . THR C 3 203 ? 13.272  12.458  38.318 1   52.56  ? 444 THR P CA  1 
ATOM   4756  C  C   . THR C 3 203 ? 13.766  12.625  36.883 1   51.02  ? 444 THR P C   1 
ATOM   4757  O  O   . THR C 3 203 ? 12.999  12.295  35.963 1   53.16  ? 444 THR P O   1 
ATOM   4758  C  CB  . THR C 3 203 ? 13.273  10.991  38.776 1   54.03  ? 444 THR P CB  1 
ATOM   4759  O  OG1 . THR C 3 203 ? 13.128  10.99   40.194 1   55.62  ? 444 THR P OG1 1 
ATOM   4760  C  CG2 . THR C 3 203 ? 14.534  10.228  38.432 1   54.98  ? 444 THR P CG2 1 
ATOM   4761  N  N   . GLN C 3 204 ? 14.982  13.136  36.712 1   50.15  ? 445 GLN P N   1 
ATOM   4762  C  CA  . GLN C 3 204 ? 15.598  13.394  35.39  1   50.66  ? 445 GLN P CA  1 
ATOM   4763  C  C   . GLN C 3 204 ? 16.781  12.443  35.208 1   48.07  ? 445 GLN P C   1 
ATOM   4764  O  O   . GLN C 3 204 ? 17.555  12.287  36.167 1   46.37  ? 445 GLN P O   1 
ATOM   4765  C  CB  . GLN C 3 204 ? 16.036  14.854  35.316 1   53.69  ? 445 GLN P CB  1 
ATOM   4766  C  CG  . GLN C 3 204 ? 16.449  15.297  33.922 1   56     ? 445 GLN P CG  1 
ATOM   4767  C  CD  . GLN C 3 204 ? 16.913  16.732  33.907 1   58.35  ? 445 GLN P CD  1 
ATOM   4768  O  OE1 . GLN C 3 204 ? 16.852  17.436  34.913 1   59.61  ? 445 GLN P OE1 1 
ATOM   4769  N  NE2 . GLN C 3 204 ? 17.401  17.168  32.757 1   59.62  ? 445 GLN P NE2 1 
ATOM   4770  N  N   . LYS C 3 205 ? 16.894  11.824  34.032 1   48.11  ? 446 LYS P N   1 
ATOM   4771  C  CA  . LYS C 3 205 ? 18.109  11.094  33.581 1   49.82  ? 446 LYS P CA  1 
ATOM   4772  C  C   . LYS C 3 205 ? 18.529  11.666  32.225 1   49.87  ? 446 LYS P C   1 
ATOM   4773  O  O   . LYS C 3 205 ? 17.656  11.787  31.338 1   47.24  ? 446 LYS P O   1 
ATOM   4774  C  CB  . LYS C 3 205 ? 17.859  9.583   33.518 1   51.27  ? 446 LYS P CB  1 
ATOM   4775  C  CG  . LYS C 3 205 ? 17.724  8.885   34.866 1   53.21  ? 446 LYS P CG  1 
ATOM   4776  C  CD  . LYS C 3 205 ? 18.992  8.9     35.701 1   56.45  ? 446 LYS P CD  1 
ATOM   4777  C  CE  . LYS C 3 205 ? 18.815  8.268   37.063 1   60.06  ? 446 LYS P CE  1 
ATOM   4778  N  NZ  . LYS C 3 205 ? 18.803  6.789   36.976 1   63.68  ? 446 LYS P NZ  1 
ATOM   4779  N  N   . THR C 3 206 ? 19.813  12.019  32.099 1   49.6   ? 447 THR P N   1 
ATOM   4780  C  CA  . THR C 3 206 ? 20.421  12.719  30.936 1   50.08  ? 447 THR P CA  1 
ATOM   4781  C  C   . THR C 3 206 ? 21.493  11.802  30.336 1   48.43  ? 447 THR P C   1 
ATOM   4782  O  O   . THR C 3 206 ? 22.268  11.228  31.116 1   49.15  ? 447 THR P O   1 
ATOM   4783  C  CB  . THR C 3 206 ? 20.948  14.097  31.371 1   51     ? 447 THR P CB  1 
ATOM   4784  O  OG1 . THR C 3 206 ? 19.823  14.914  31.71  1   52.38  ? 447 THR P OG1 1 
ATOM   4785  C  CG2 . THR C 3 206 ? 21.765  14.805  30.313 1   51.38  ? 447 THR P CG2 1 
ATOM   4786  N  N   . ILE C 3 207 ? 21.537  11.688  29.007 1   49.37  ? 448 ILE P N   1 
ATOM   4787  C  CA  . ILE C 3 207 ? 22.441  10.758  28.265 1   53.21  ? 448 ILE P CA  1 
ATOM   4788  C  C   . ILE C 3 207 ? 23.045  11.481  27.05  1   53.59  ? 448 ILE P C   1 
ATOM   4789  O  O   . ILE C 3 207 ? 22.383  12.387  26.505 1   52.34  ? 448 ILE P O   1 
ATOM   4790  C  CB  . ILE C 3 207 ? 21.671  9.474   27.88  1   55.31  ? 448 ILE P CB  1 
ATOM   4791  C  CG1 . ILE C 3 207 ? 22.612  8.283   27.71  1   57.87  ? 448 ILE P CG1 1 
ATOM   4792  C  CG2 . ILE C 3 207 ? 20.789  9.68    26.65  1   55.6   ? 448 ILE P CG2 1 
ATOM   4793  C  CD1 . ILE C 3 207 ? 21.905  6.985   27.406 1   60.58  ? 448 ILE P CD1 1 
ATOM   4794  N  N   . ASP C 3 208 ? 24.262  11.089  26.656 1   57.18  ? 449 ASP P N   1 
ATOM   4795  C  CA  . ASP C 3 208 ? 24.943  11.514  25.398 1   60.1   ? 449 ASP P CA  1 
ATOM   4796  C  C   . ASP C 3 208 ? 25.965  10.44   24.998 1   62.68  ? 449 ASP P C   1 
ATOM   4797  O  O   . ASP C 3 208 ? 26.118  9.454   25.761 1   63.2   ? 449 ASP P O   1 
ATOM   4798  C  CB  . ASP C 3 208 ? 25.57   12.906  25.54  1   59.93  ? 449 ASP P CB  1 
ATOM   4799  C  CG  . ASP C 3 208 ? 26.535  13.079  26.704 1   61.62  ? 449 ASP P CG  1 
ATOM   4800  O  OD1 . ASP C 3 208 ? 27.223  12.098  27.075 1   60.34  ? 449 ASP P OD1 1 
ATOM   4801  O  OD2 . ASP C 3 208 ? 26.602  14.209  27.228 1   62.95  ? 449 ASP P OD2 1 
ATOM   4802  N  N   . ARG C 3 209 ? 26.66   10.634  23.868 1   64.16  ? 450 ARG P N   1 
ATOM   4803  C  CA  . ARG C 3 209 ? 27.653  9.666   23.316 1   63.22  ? 450 ARG P CA  1 
ATOM   4804  C  C   . ARG C 3 209 ? 28.844  9.486   24.269 1   64.78  ? 450 ARG P C   1 
ATOM   4805  O  O   . ARG C 3 209 ? 29.532  8.468   24.118 1   68.66  ? 450 ARG P O   1 
ATOM   4806  C  CB  . ARG C 3 209 ? 28.129  10.091  21.921 1   62.68  ? 450 ARG P CB  1 
ATOM   4807  C  CG  . ARG C 3 209 ? 29.011  11.333  21.879 1   62.98  ? 450 ARG P CG  1 
ATOM   4808  C  CD  . ARG C 3 209 ? 29.592  11.566  20.496 1   62.98  ? 450 ARG P CD  1 
ATOM   4809  N  NE  . ARG C 3 209 ? 30.781  10.767  20.23  1   62.39  ? 450 ARG P NE  1 
ATOM   4810  C  CZ  . ARG C 3 209 ? 31.437  10.701  19.058 0   66.12  ? 450 ARG P CZ  1 
ATOM   4811  N  NH1 . ARG C 3 209 ? 31.081  11.476  18.045 0   66.16  ? 450 ARG P NH1 1 
ATOM   4812  N  NH2 . ARG C 3 209 ? 32.478  9.899   18.918 0   66.15  ? 450 ARG P NH2 1 
ATOM   4813  N  N   . LEU C 3 210 ? 29.066  10.407  25.217 1   68.87  ? 451 LEU P N   1 
ATOM   4814  C  CA  . LEU C 3 210 ? 30.26   10.448  26.109 1   73.83  ? 451 LEU P CA  1 
ATOM   4815  C  C   . LEU C 3 210 ? 30.006  9.664   27.411 1   76.26  ? 451 LEU P C   1 
ATOM   4816  O  O   . LEU C 3 210 ? 30.449  10.14   28.474 1   79     ? 451 LEU P O   1 
ATOM   4817  C  CB  . LEU C 3 210 ? 30.599  11.916  26.413 1   76.44  ? 451 LEU P CB  1 
ATOM   4818  C  CG  . LEU C 3 210 ? 30.745  12.853  25.211 1   79.07  ? 451 LEU P CG  1 
ATOM   4819  C  CD1 . LEU C 3 210 ? 30.701  14.306  25.658 1   80.09  ? 451 LEU P CD1 1 
ATOM   4820  C  CD2 . LEU C 3 210 ? 32.03   12.57   24.445 1   79.81  ? 451 LEU P CD2 1 
ATOM   4821  N  N   . ALA C 3 211 ? 29.354  8.497   27.352 1   79.17  ? 452 ALA P N   1 
ATOM   4822  C  CA  . ALA C 3 211 ? 29.116  7.617   28.524 1   81.65  ? 452 ALA P CA  1 
ATOM   4823  C  C   . ALA C 3 211 ? 28.74   6.204   28.06  1   84.56  ? 452 ALA P C   1 
ATOM   4824  O  O   . ALA C 3 211 ? 27.727  6.008   27.391 1   89.65  ? 452 ALA P O   1 
ATOM   4825  C  CB  . ALA C 3 211 ? 28.048  8.209   29.411 1   81.56  ? 452 ALA P CB  1 
ATOM   4826  N  N   . CYS D 3 1   ? -28.488 1.332   20.787 1   153.71 ? 242 CYS Q N   1 
ATOM   4827  C  CA  . CYS D 3 1   ? -27.807 2.353   19.919 1   156.34 ? 242 CYS Q CA  1 
ATOM   4828  C  C   . CYS D 3 1   ? -27.728 1.853   18.467 1   163.88 ? 242 CYS Q C   1 
ATOM   4829  O  O   . CYS D 3 1   ? -28.256 0.753   18.193 1   168.17 ? 242 CYS Q O   1 
ATOM   4830  C  CB  . CYS D 3 1   ? -26.414 2.683   20.447 1   152.55 ? 242 CYS Q CB  1 
ATOM   4831  S  SG  . CYS D 3 1   ? -25.7   4.174   19.713 0   153.89 ? 242 CYS Q SG  1 
ATOM   4832  N  N   . HIS D 3 2   ? -27.098 2.638   17.582 1   169.57 ? 243 HIS Q N   1 
ATOM   4833  C  CA  . HIS D 3 2   ? -26.956 2.378   16.12  1   172.16 ? 243 HIS Q CA  1 
ATOM   4834  C  C   . HIS D 3 2   ? -26.237 1.045   15.896 1   177.38 ? 243 HIS Q C   1 
ATOM   4835  O  O   . HIS D 3 2   ? -25.085 0.911   16.303 1   183.4  ? 243 HIS Q O   1 
ATOM   4836  C  CB  . HIS D 3 2   ? -26.218 3.549   15.445 1   169.15 ? 243 HIS Q CB  1 
ATOM   4837  C  CG  . HIS D 3 2   ? -26.307 3.559   13.955 1   167.53 ? 243 HIS Q CG  1 
ATOM   4838  N  ND1 . HIS D 3 2   ? -27.24  4.322   13.278 1   166.64 ? 243 HIS Q ND1 1 
ATOM   4839  C  CD2 . HIS D 3 2   ? -25.583 2.921   13.011 1   165.72 ? 243 HIS Q CD2 1 
ATOM   4840  C  CE1 . HIS D 3 2   ? -27.091 4.148   11.981 1   163.87 ? 243 HIS Q CE1 1 
ATOM   4841  N  NE2 . HIS D 3 2   ? -26.08  3.292   11.79  1   164.44 ? 243 HIS Q NE2 1 
ATOM   4842  N  N   . PRO D 3 3   ? -26.881 0.015   15.282 1   178.36 ? 244 PRO Q N   1 
ATOM   4843  C  CA  . PRO D 3 3   ? -26.21  -1.258  14.992 1   175.19 ? 244 PRO Q CA  1 
ATOM   4844  C  C   . PRO D 3 3   ? -24.962 -1.117  14.102 1   172.7  ? 244 PRO Q C   1 
ATOM   4845  O  O   . PRO D 3 3   ? -25.04  -0.421  13.102 1   175.43 ? 244 PRO Q O   1 
ATOM   4846  C  CB  . PRO D 3 3   ? -27.273 -2.093  14.256 1   174.13 ? 244 PRO Q CB  1 
ATOM   4847  C  CG  . PRO D 3 3   ? -28.591 -1.483  14.674 1   174.29 ? 244 PRO Q CG  1 
ATOM   4848  C  CD  . PRO D 3 3   ? -28.298 -0.012  14.88  1   176.45 ? 244 PRO Q CD  1 
ATOM   4849  N  N   . ARG D 3 4   ? -23.861 -1.773  14.491 1   165.31 ? 245 ARG Q N   1 
ATOM   4850  C  CA  . ARG D 3 4   ? -22.547 -1.762  13.786 1   157.74 ? 245 ARG Q CA  1 
ATOM   4851  C  C   . ARG D 3 4   ? -22.058 -3.204  13.59  1   150.41 ? 245 ARG Q C   1 
ATOM   4852  O  O   . ARG D 3 4   ? -22.454 -4.079  14.39  1   147.59 ? 245 ARG Q O   1 
ATOM   4853  C  CB  . ARG D 3 4   ? -21.52  -0.943  14.577 1   155.66 ? 245 ARG Q CB  1 
ATOM   4854  C  CG  . ARG D 3 4   ? -21.806 0.552   14.616 1   152.42 ? 245 ARG Q CG  1 
ATOM   4855  C  CD  . ARG D 3 4   ? -20.623 1.357   15.122 1   149.03 ? 245 ARG Q CD  1 
ATOM   4856  N  NE  . ARG D 3 4   ? -20.354 1.164   16.529 0   160.75 ? 245 ARG Q NE  1 
ATOM   4857  C  CZ  . ARG D 3 4   ? -21.031 1.709   17.541 0   160.44 ? 245 ARG Q CZ  1 
ATOM   4858  N  NH1 . ARG D 3 4   ? -22.063 2.512   17.333 0   160.36 ? 245 ARG Q NH1 1 
ATOM   4859  N  NH2 . ARG D 3 4   ? -20.668 1.437   18.781 0   160.35 ? 245 ARG Q NH2 1 
ATOM   4860  N  N   . LEU D 3 5   ? -21.23  -3.431  12.562 1   143.42 ? 246 LEU Q N   1 
ATOM   4861  C  CA  . LEU D 3 5   ? -20.63  -4.752  12.22  1   138.05 ? 246 LEU Q CA  1 
ATOM   4862  C  C   . LEU D 3 5   ? -19.179 -4.556  11.756 1   133.93 ? 246 LEU Q C   1 
ATOM   4863  O  O   . LEU D 3 5   ? -18.935 -3.623  10.964 1   131.3  ? 246 LEU Q O   1 
ATOM   4864  C  CB  . LEU D 3 5   ? -21.469 -5.417  11.124 1   133.98 ? 246 LEU Q CB  1 
ATOM   4865  C  CG  . LEU D 3 5   ? -21.255 -6.921  10.95  1   130.65 ? 246 LEU Q CG  1 
ATOM   4866  C  CD1 . LEU D 3 5   ? -22.024 -7.7    12.003 1   127.72 ? 246 LEU Q CD1 1 
ATOM   4867  C  CD2 . LEU D 3 5   ? -21.661 -7.378  9.557  1   131.18 ? 246 LEU Q CD2 1 
ATOM   4868  N  N   . SER D 3 6   ? -18.264 -5.408  12.235 1   131.81 ? 247 SER Q N   1 
ATOM   4869  C  CA  . SER D 3 6   ? -16.839 -5.483  11.807 1   128.97 ? 247 SER Q CA  1 
ATOM   4870  C  C   . SER D 3 6   ? -16.346 -6.936  11.867 1   124.44 ? 247 SER Q C   1 
ATOM   4871  O  O   . SER D 3 6   ? -16.841 -7.695  12.729 1   121.91 ? 247 SER Q O   1 
ATOM   4872  C  CB  . SER D 3 6   ? -15.964 -4.572  12.638 1   126.65 ? 247 SER Q CB  1 
ATOM   4873  O  OG  . SER D 3 6   ? -15.961 -4.963  14.004 1   125.05 ? 247 SER Q OG  1 
ATOM   4874  N  N   . LEU D 3 7   ? -15.414 -7.298  10.976 1   118.28 ? 248 LEU Q N   1 
ATOM   4875  C  CA  . LEU D 3 7   ? -14.699 -8.606  10.978 1   115.71 ? 248 LEU Q CA  1 
ATOM   4876  C  C   . LEU D 3 7   ? -13.423 -8.468  11.818 1   109.87 ? 248 LEU Q C   1 
ATOM   4877  O  O   . LEU D 3 7   ? -12.871 -7.349  11.873 1   110.34 ? 248 LEU Q O   1 
ATOM   4878  C  CB  . LEU D 3 7   ? -14.375 -9.037  9.541  1   117.5  ? 248 LEU Q CB  1 
ATOM   4879  C  CG  . LEU D 3 7   ? -15.428 -9.913  8.861  1   116.23 ? 248 LEU Q CG  1 
ATOM   4880  C  CD1 . LEU D 3 7   ? -15.238 -9.932  7.356  0   116.88 ? 248 LEU Q CD1 1 
ATOM   4881  C  CD2 . LEU D 3 7   ? -15.386 -11.339 9.415  0   116.82 ? 248 LEU Q CD2 1 
ATOM   4882  N  N   . HIS D 3 8   ? -12.985 -9.565  12.446 1   103.91 ? 249 HIS Q N   1 
ATOM   4883  C  CA  . HIS D 3 8   ? -11.73  -9.662  13.24  1   101.38 ? 249 HIS Q CA  1 
ATOM   4884  C  C   . HIS D 3 8   ? -10.78  -10.657 12.567 1   96.62  ? 249 HIS Q C   1 
ATOM   4885  O  O   . HIS D 3 8   ? -11.225 -11.779 12.248 1   91.76  ? 249 HIS Q O   1 
ATOM   4886  C  CB  . HIS D 3 8   ? -12.037 -10.028 14.699 1   104.11 ? 249 HIS Q CB  1 
ATOM   4887  C  CG  . HIS D 3 8   ? -12.888 -9.018  15.389 1   105.92 ? 249 HIS Q CG  1 
ATOM   4888  N  ND1 . HIS D 3 8   ? -12.641 -7.66   15.296 1   107.5  ? 249 HIS Q ND1 1 
ATOM   4889  C  CD2 . HIS D 3 8   ? -13.98  -9.154  16.171 1   107.28 ? 249 HIS Q CD2 1 
ATOM   4890  C  CE1 . HIS D 3 8   ? -13.545 -7.003  15.992 1   109    ? 249 HIS Q CE1 1 
ATOM   4891  N  NE2 . HIS D 3 8   ? -14.379 -7.898  16.539 1   110.47 ? 249 HIS Q NE2 1 
ATOM   4892  N  N   . ARG D 3 9   ? -9.521  -10.247 12.374 1   95.5   ? 250 ARG Q N   1 
ATOM   4893  C  CA  . ARG D 3 9   ? -8.464  -10.997 11.637 1   92.04  ? 250 ARG Q CA  1 
ATOM   4894  C  C   . ARG D 3 9   ? -8.113  -12.29  12.377 1   88.05  ? 250 ARG Q C   1 
ATOM   4895  O  O   . ARG D 3 9   ? -8.406  -12.417 13.565 1   89.85  ? 250 ARG Q O   1 
ATOM   4896  C  CB  . ARG D 3 9   ? -7.224  -10.113 11.453 1   91.98  ? 250 ARG Q CB  1 
ATOM   4897  C  CG  . ARG D 3 9   ? -6.559  -9.662  12.749 1   91.63  ? 250 ARG Q CG  1 
ATOM   4898  C  CD  . ARG D 3 9   ? -5.104  -9.302  12.536 1   91.22  ? 250 ARG Q CD  1 
ATOM   4899  N  NE  . ARG D 3 9   ? -4.287  -10.478 12.257 1   90.41  ? 250 ARG Q NE  1 
ATOM   4900  C  CZ  . ARG D 3 9   ? -3.016  -10.458 11.854 1   92.41  ? 250 ARG Q CZ  1 
ATOM   4901  N  NH1 . ARG D 3 9   ? -2.374  -9.311  11.675 1   91.55  ? 250 ARG Q NH1 1 
ATOM   4902  N  NH2 . ARG D 3 9   ? -2.388  -11.601 11.629 1   93.06  ? 250 ARG Q NH2 1 
ATOM   4903  N  N   . PRO D 3 10  ? -7.452  -13.278 11.723 1   84.64  ? 251 PRO Q N   1 
ATOM   4904  C  CA  . PRO D 3 10  ? -7.056  -14.511 12.402 1   82.37  ? 251 PRO Q CA  1 
ATOM   4905  C  C   . PRO D 3 10  ? -5.88   -14.281 13.365 1   80.73  ? 251 PRO Q C   1 
ATOM   4906  O  O   . PRO D 3 10  ? -5.163  -13.303 13.208 1   81.8   ? 251 PRO Q O   1 
ATOM   4907  C  CB  . PRO D 3 10  ? -6.651  -15.485 11.28  1   83.32  ? 251 PRO Q CB  1 
ATOM   4908  C  CG  . PRO D 3 10  ? -6.867  -14.735 9.969  1   83.85  ? 251 PRO Q CG  1 
ATOM   4909  C  CD  . PRO D 3 10  ? -7.021  -13.268 10.316 1   83.33  ? 251 PRO Q CD  1 
ATOM   4910  N  N   . ALA D 3 11  ? -5.712  -15.193 14.327 1   80.36  ? 252 ALA Q N   1 
ATOM   4911  C  CA  . ALA D 3 11  ? -4.663  -15.158 15.374 1   75.13  ? 252 ALA Q CA  1 
ATOM   4912  C  C   . ALA D 3 11  ? -3.284  -15.198 14.71  1   72.16  ? 252 ALA Q C   1 
ATOM   4913  O  O   . ALA D 3 11  ? -3.037  -16.118 13.899 1   69.14  ? 252 ALA Q O   1 
ATOM   4914  C  CB  . ALA D 3 11  ? -4.835  -16.31  16.335 1   76.11  ? 252 ALA Q CB  1 
ATOM   4915  N  N   . LEU D 3 12  ? -2.428  -14.228 15.044 1   69.97  ? 253 LEU Q N   1 
ATOM   4916  C  CA  . LEU D 3 12  ? -1.036  -14.128 14.531 1   65.88  ? 253 LEU Q CA  1 
ATOM   4917  C  C   . LEU D 3 12  ? -0.239  -15.368 14.958 1   65.94  ? 253 LEU Q C   1 
ATOM   4918  O  O   . LEU D 3 12  ? 0.549   -15.854 14.127 1   64.81  ? 253 LEU Q O   1 
ATOM   4919  C  CB  . LEU D 3 12  ? -0.404  -12.833 15.052 1   62.42  ? 253 LEU Q CB  1 
ATOM   4920  C  CG  . LEU D 3 12  ? 1.004   -12.523 14.551 1   60.36  ? 253 LEU Q CG  1 
ATOM   4921  C  CD1 . LEU D 3 12  ? 1.049   -12.389 13.035 1   58.91  ? 253 LEU Q CD1 1 
ATOM   4922  C  CD2 . LEU D 3 12  ? 1.531   -11.259 15.207 1   61.34  ? 253 LEU Q CD2 1 
ATOM   4923  N  N   . GLU D 3 13  ? -0.454  -15.862 16.187 1   70.42  ? 254 GLU Q N   1 
ATOM   4924  C  CA  . GLU D 3 13  ? 0.154   -17.114 16.73  1   76.03  ? 254 GLU Q CA  1 
ATOM   4925  C  C   . GLU D 3 13  ? -0.058  -18.262 15.737 1   77.77  ? 254 GLU Q C   1 
ATOM   4926  O  O   . GLU D 3 13  ? 0.945   -18.888 15.336 1   79.25  ? 254 GLU Q O   1 
ATOM   4927  C  CB  . GLU D 3 13  ? -0.46   -17.524 18.073 1   79.48  ? 254 GLU Q CB  1 
ATOM   4928  C  CG  . GLU D 3 13  ? -0.165  -16.572 19.219 1   83.13  ? 254 GLU Q CG  1 
ATOM   4929  C  CD  . GLU D 3 13  ? -1.242  -15.539 19.517 1   86.64  ? 254 GLU Q CD  1 
ATOM   4930  O  OE1 . GLU D 3 13  ? -1.945  -15.115 18.571 1   85.63  ? 254 GLU Q OE1 1 
ATOM   4931  O  OE2 . GLU D 3 13  ? -1.373  -15.157 20.698 1   89.64  ? 254 GLU Q OE2 1 
ATOM   4932  N  N   . ASP D 3 14  ? -1.317  -18.5   15.353 1   79.05  ? 255 ASP Q N   1 
ATOM   4933  C  CA  . ASP D 3 14  ? -1.747  -19.635 14.49  1   77.72  ? 255 ASP Q CA  1 
ATOM   4934  C  C   . ASP D 3 14  ? -1.125  -19.478 13.097 1   74.08  ? 255 ASP Q C   1 
ATOM   4935  O  O   . ASP D 3 14  ? -0.567  -20.471 12.589 1   76.01  ? 255 ASP Q O   1 
ATOM   4936  C  CB  . ASP D 3 14  ? -3.275  -19.738 14.414 1   77.74  ? 255 ASP Q CB  1 
ATOM   4937  C  CG  . ASP D 3 14  ? -3.966  -19.971 15.75  1   79.01  ? 255 ASP Q CG  1 
ATOM   4938  O  OD1 . ASP D 3 14  ? -3.273  -20.307 16.731 1   81.08  ? 255 ASP Q OD1 1 
ATOM   4939  O  OD2 . ASP D 3 14  ? -5.2    -19.811 15.799 1   82.48  ? 255 ASP Q OD2 1 
ATOM   4940  N  N   . LEU D 3 15  ? -1.202  -18.274 12.521 1   69.41  ? 256 LEU Q N   1 
ATOM   4941  C  CA  . LEU D 3 15  ? -0.678  -17.958 11.164 1   69.02  ? 256 LEU Q CA  1 
ATOM   4942  C  C   . LEU D 3 15  ? 0.847   -18.132 11.121 1   67.72  ? 256 LEU Q C   1 
ATOM   4943  O  O   . LEU D 3 15  ? 1.333   -18.69  10.121 1   61.3   ? 256 LEU Q O   1 
ATOM   4944  C  CB  . LEU D 3 15  ? -1.085  -16.533 10.777 1   70.5   ? 256 LEU Q CB  1 
ATOM   4945  C  CG  . LEU D 3 15  ? -2.553  -16.36  10.391 1   70.81  ? 256 LEU Q CG  1 
ATOM   4946  C  CD1 . LEU D 3 15  ? -2.984  -14.911 10.527 1   70.09  ? 256 LEU Q CD1 1 
ATOM   4947  C  CD2 . LEU D 3 15  ? -2.808  -16.863 8.977  1   70.68  ? 256 LEU Q CD2 1 
ATOM   4948  N  N   . LEU D 3 16  ? 1.569   -17.678 12.154 1   71.91  ? 257 LEU Q N   1 
ATOM   4949  C  CA  . LEU D 3 16  ? 3.061   -17.652 12.171 1   75.59  ? 257 LEU Q CA  1 
ATOM   4950  C  C   . LEU D 3 16  ? 3.617   -19.068 12.35  1   78.84  ? 257 LEU Q C   1 
ATOM   4951  O  O   . LEU D 3 16  ? 4.653   -19.366 11.719 1   76.21  ? 257 LEU Q O   1 
ATOM   4952  C  CB  . LEU D 3 16  ? 3.574   -16.717 13.274 1   74.89  ? 257 LEU Q CB  1 
ATOM   4953  C  CG  . LEU D 3 16  ? 3.577   -15.223 12.947 1   73.16  ? 257 LEU Q CG  1 
ATOM   4954  C  CD1 . LEU D 3 16  ? 4.02    -14.422 14.159 1   73.97  ? 257 LEU Q CD1 1 
ATOM   4955  C  CD2 . LEU D 3 16  ? 4.477   -14.902 11.761 1   72.43  ? 257 LEU Q CD2 1 
ATOM   4956  N  N   . LEU D 3 17  ? 2.969   -19.893 13.181 1   82.31  ? 258 LEU Q N   1 
ATOM   4957  C  CA  . LEU D 3 17  ? 3.291   -21.339 13.338 1   87.01  ? 258 LEU Q CA  1 
ATOM   4958  C  C   . LEU D 3 17  ? 3.033   -22.083 12.018 1   90.48  ? 258 LEU Q C   1 
ATOM   4959  O  O   . LEU D 3 17  ? 3.779   -23.04  11.731 1   91.19  ? 258 LEU Q O   1 
ATOM   4960  C  CB  . LEU D 3 17  ? 2.459   -21.927 14.484 1   88.28  ? 258 LEU Q CB  1 
ATOM   4961  C  CG  . LEU D 3 17  ? 2.823   -21.429 15.883 1   89.9   ? 258 LEU Q CG  1 
ATOM   4962  C  CD1 . LEU D 3 17  ? 1.725   -21.755 16.884 1   90.97  ? 258 LEU Q CD1 1 
ATOM   4963  C  CD2 . LEU D 3 17  ? 4.147   -22.013 16.344 1   89.96  ? 258 LEU Q CD2 1 
ATOM   4964  N  N   . GLY D 3 18  ? 2.03    -21.657 11.241 1   95.17  ? 259 GLY Q N   1 
ATOM   4965  C  CA  . GLY D 3 18  ? 1.625   -22.295 9.972  1   96.91  ? 259 GLY Q CA  1 
ATOM   4966  C  C   . GLY D 3 18  ? 0.616   -23.409 10.199 1   98.94  ? 259 GLY Q C   1 
ATOM   4967  O  O   . GLY D 3 18  ? 0.669   -24.407 9.456  1   97.92  ? 259 GLY Q O   1 
ATOM   4968  N  N   . SER D 3 19  ? -0.263  -23.244 11.195 1   101.49 ? 260 SER Q N   1 
ATOM   4969  C  CA  . SER D 3 19  ? -1.393  -24.151 11.529 1   106.31 ? 260 SER Q CA  1 
ATOM   4970  C  C   . SER D 3 19  ? -2.716  -23.463 11.158 1   112.72 ? 260 SER Q C   1 
ATOM   4971  O  O   . SER D 3 19  ? -2.664  -22.303 10.69  1   115.86 ? 260 SER Q O   1 
ATOM   4972  C  CB  . SER D 3 19  ? -1.345  -24.551 12.985 1   103.87 ? 260 SER Q CB  1 
ATOM   4973  O  OG  . SER D 3 19  ? -1.343  -23.41  13.828 1   102.09 ? 260 SER Q OG  1 
ATOM   4974  N  N   . GLU D 3 20  ? -3.849  -24.155 11.34  1   112.73 ? 261 GLU Q N   1 
ATOM   4975  C  CA  . GLU D 3 20  ? -5.213  -23.658 10.995 1   111.83 ? 261 GLU Q CA  1 
ATOM   4976  C  C   . GLU D 3 20  ? -5.573  -22.473 11.901 1   108.62 ? 261 GLU Q C   1 
ATOM   4977  O  O   . GLU D 3 20  ? -5.284  -22.555 13.112 1   103.96 ? 261 GLU Q O   1 
ATOM   4978  C  CB  . GLU D 3 20  ? -6.246  -24.781 11.128 1   113.39 ? 261 GLU Q CB  1 
ATOM   4979  C  CG  . GLU D 3 20  ? -6.046  -25.898 10.123 0   116.79 ? 261 GLU Q CG  1 
ATOM   4980  C  CD  . GLU D 3 20  ? -7.098  -26.994 10.156 0   116.8  ? 261 GLU Q CD  1 
ATOM   4981  O  OE1 . GLU D 3 20  ? -7.923  -27.003 11.093 0   116.73 ? 261 GLU Q OE1 1 
ATOM   4982  O  OE2 . GLU D 3 20  ? -7.09   -27.841 9.241  0   116.68 ? 261 GLU Q OE2 1 
ATOM   4983  N  N   . ALA D 3 21  ? -6.19   -21.43  11.327 1   108.73 ? 262 ALA Q N   1 
ATOM   4984  C  CA  . ALA D 3 21  ? -6.489  -20.13  11.98  1   111.47 ? 262 ALA Q CA  1 
ATOM   4985  C  C   . ALA D 3 21  ? -7.99   -19.813 11.893 1   112.06 ? 262 ALA Q C   1 
ATOM   4986  O  O   . ALA D 3 21  ? -8.542  -19.855 10.773 1   106.63 ? 262 ALA Q O   1 
ATOM   4987  C  CB  . ALA D 3 21  ? -5.667  -19.043 11.335 1   113.22 ? 262 ALA Q CB  1 
ATOM   4988  N  N   . ASN D 3 22  ? -8.607  -19.481 13.035 1   115.02 ? 263 ASN Q N   1 
ATOM   4989  C  CA  . ASN D 3 22  ? -10.048 -19.128 13.166 1   111.41 ? 263 ASN Q CA  1 
ATOM   4990  C  C   . ASN D 3 22  ? -10.245 -17.662 12.761 1   112.32 ? 263 ASN Q C   1 
ATOM   4991  O  O   . ASN D 3 22  ? -9.544  -16.8   13.328 1   112.73 ? 263 ASN Q O   1 
ATOM   4992  C  CB  . ASN D 3 22  ? -10.57  -19.332 14.593 1   110.2  ? 263 ASN Q CB  1 
ATOM   4993  C  CG  . ASN D 3 22  ? -10.405 -20.747 15.112 1   110.87 ? 263 ASN Q CG  1 
ATOM   4994  O  OD1 . ASN D 3 22  ? -10.621 -21.712 14.38  1   110.4  ? 263 ASN Q OD1 1 
ATOM   4995  N  ND2 . ASN D 3 22  ? -10.04  -20.886 16.378 1   107.89 ? 263 ASN Q ND2 1 
ATOM   4996  N  N   . LEU D 3 23  ? -11.166 -17.399 11.828 1   114.66 ? 264 LEU Q N   1 
ATOM   4997  C  CA  . LEU D 3 23  ? -11.591 -16.036 11.401 1   116.97 ? 264 LEU Q CA  1 
ATOM   4998  C  C   . LEU D 3 23  ? -12.98  -15.748 11.989 1   118.66 ? 264 LEU Q C   1 
ATOM   4999  O  O   . LEU D 3 23  ? -13.926 -16.479 11.636 1   116.58 ? 264 LEU Q O   1 
ATOM   5000  C  CB  . LEU D 3 23  ? -11.594 -15.981 9.87   1   116.17 ? 264 LEU Q CB  1 
ATOM   5001  C  CG  . LEU D 3 23  ? -11.762 -14.596 9.247  1   116.19 ? 264 LEU Q CG  1 
ATOM   5002  C  CD1 . LEU D 3 23  ? -10.526 -13.737 9.462  1   116.89 ? 264 LEU Q CD1 1 
ATOM   5003  C  CD2 . LEU D 3 23  ? -12.062 -14.711 7.764  1   117.3  ? 264 LEU Q CD2 1 
ATOM   5004  N  N   . THR D 3 24  ? -13.089 -14.72  12.841 1   123.15 ? 265 THR Q N   1 
ATOM   5005  C  CA  . THR D 3 24  ? -14.264 -14.432 13.713 1   126.89 ? 265 THR Q CA  1 
ATOM   5006  C  C   . THR D 3 24  ? -15.051 -13.227 13.176 1   132.45 ? 265 THR Q C   1 
ATOM   5007  O  O   . THR D 3 24  ? -14.421 -12.296 12.63  1   131.74 ? 265 THR Q O   1 
ATOM   5008  C  CB  . THR D 3 24  ? -13.806 -14.228 15.165 1   124.37 ? 265 THR Q CB  1 
ATOM   5009  O  OG1 . THR D 3 24  ? -13.254 -15.472 15.596 1   120.45 ? 265 THR Q OG1 1 
ATOM   5010  C  CG2 . THR D 3 24  ? -14.91  -13.806 16.113 1   122.44 ? 265 THR Q CG2 1 
ATOM   5011  N  N   . CYS D 3 25  ? -16.38  -13.257 13.349 1   138.74 ? 266 CYS Q N   1 
ATOM   5012  C  CA  . CYS D 3 25  ? -17.336 -12.154 13.052 1   142.98 ? 266 CYS Q CA  1 
ATOM   5013  C  C   . CYS D 3 25  ? -18.327 -12.006 14.215 1   146.11 ? 266 CYS Q C   1 
ATOM   5014  O  O   . CYS D 3 25  ? -18.799 -13.047 14.716 1   141.65 ? 266 CYS Q O   1 
ATOM   5015  C  CB  . CYS D 3 25  ? -18.094 -12.418 11.758 1   142.81 ? 266 CYS Q CB  1 
ATOM   5016  S  SG  . CYS D 3 25  ? -19.148 -11.035 11.249 1   145.9  ? 266 CYS Q SG  1 
ATOM   5017  N  N   . THR D 3 26  ? -18.631 -10.764 14.612 1   152.01 ? 267 THR Q N   1 
ATOM   5018  C  CA  . THR D 3 26  ? -19.499 -10.41  15.772 1   157.59 ? 267 THR Q CA  1 
ATOM   5019  C  C   . THR D 3 26  ? -20.488 -9.305  15.372 1   162.56 ? 267 THR Q C   1 
ATOM   5020  O  O   . THR D 3 26  ? -20.145 -8.511  14.471 1   164.07 ? 267 THR Q O   1 
ATOM   5021  C  CB  . THR D 3 26  ? -18.648 -9.989  16.977 1   153.7  ? 267 THR Q CB  1 
ATOM   5022  O  OG1 . THR D 3 26  ? -17.816 -8.895  16.593 0   163.25 ? 267 THR Q OG1 1 
ATOM   5023  C  CG2 . THR D 3 26  ? -17.79  -11.12  17.505 0   162.86 ? 267 THR Q CG2 1 
ATOM   5024  N  N   . LEU D 3 27  ? -21.655 -9.261  16.032 1   162.77 ? 268 LEU Q N   1 
ATOM   5025  C  CA  . LEU D 3 27  ? -22.769 -8.303  15.776 1   159.34 ? 268 LEU Q CA  1 
ATOM   5026  C  C   . LEU D 3 27  ? -23.014 -7.448  17.028 1   160.33 ? 268 LEU Q C   1 
ATOM   5027  O  O   . LEU D 3 27  ? -23.661 -7.952  17.966 1   157.3  ? 268 LEU Q O   1 
ATOM   5028  C  CB  . LEU D 3 27  ? -24.02  -9.099  15.386 1   156.42 ? 268 LEU Q CB  1 
ATOM   5029  C  CG  . LEU D 3 27  ? -25.282 -8.274  15.131 1   154.88 ? 268 LEU Q CG  1 
ATOM   5030  C  CD1 . LEU D 3 27  ? -25.179 -7.346  13.999 0   176.72 ? 268 LEU Q CD1 1 
ATOM   5031  C  CD2 . LEU D 3 27  ? -26.502 -9.214  15.001 0   176.69 ? 268 LEU Q CD2 1 
ATOM   5032  N  N   . THR D 3 28  ? -22.529 -6.199  17.026 1   164.47 ? 269 THR Q N   1 
ATOM   5033  C  CA  . THR D 3 28  ? -22.699 -5.202  18.122 1   167.9  ? 269 THR Q CA  1 
ATOM   5034  C  C   . THR D 3 28  ? -23.978 -4.386  17.885 1   171.37 ? 269 THR Q C   1 
ATOM   5035  O  O   . THR D 3 28  ? -24.35  -4.195  16.707 1   174.23 ? 269 THR Q O   1 
ATOM   5036  C  CB  . THR D 3 28  ? -21.474 -4.285  18.234 1   163.85 ? 269 THR Q CB  1 
ATOM   5037  O  OG1 . THR D 3 28  ? -21.225 -3.674  16.991 0   183.3  ? 269 THR Q OG1 1 
ATOM   5038  C  CG2 . THR D 3 28  ? -20.232 -5.04   18.703 0   182.97 ? 269 THR Q CG2 1 
ATOM   5039  N  N   . GLY D 3 29  ? -24.615 -3.923  18.967 1   170.52 ? 270 GLY Q N   1 
ATOM   5040  C  CA  . GLY D 3 29  ? -25.866 -3.139  18.94  1   169.7  ? 270 GLY Q CA  1 
ATOM   5041  C  C   . GLY D 3 29  ? -27.091 -4.037  18.932 1   168.37 ? 270 GLY Q C   1 
ATOM   5042  O  O   . GLY D 3 29  ? -28.086 -3.631  18.303 1   168.97 ? 270 GLY Q O   1 
ATOM   5043  N  N   . ASP D 3 32  ? -32.438 -8.067  20.887 1   125.59 ? 273 ASP Q N   1 
ATOM   5044  C  CA  . ASP D 3 32  ? -33.091 -8.948  19.877 1   130.2  ? 273 ASP Q CA  1 
ATOM   5045  C  C   . ASP D 3 32  ? -32.592 -10.389 20.048 1   130.23 ? 273 ASP Q C   1 
ATOM   5046  O  O   . ASP D 3 32  ? -31.378 -10.57  20.267 1   124.74 ? 273 ASP Q O   1 
ATOM   5047  C  CB  . ASP D 3 32  ? -32.841 -8.439  18.453 1   135.43 ? 273 ASP Q CB  1 
ATOM   5048  C  CG  . ASP D 3 32  ? -33.459 -9.285  17.347 1   138.34 ? 273 ASP Q CG  1 
ATOM   5049  O  OD1 . ASP D 3 32  ? -34.566 -9.82   17.561 1   139.43 ? 273 ASP Q OD1 1 
ATOM   5050  O  OD2 . ASP D 3 32  ? -32.83  -9.394  16.274 1   138.69 ? 273 ASP Q OD2 1 
ATOM   5051  N  N   . ALA D 3 33  ? -33.502 -11.364 19.935 1   136.24 ? 274 ALA Q N   1 
ATOM   5052  C  CA  . ALA D 3 33  ? -33.222 -12.819 20.015 1   139.14 ? 274 ALA Q CA  1 
ATOM   5053  C  C   . ALA D 3 33  ? -32.416 -13.261 18.786 1   142.1  ? 274 ALA Q C   1 
ATOM   5054  O  O   . ALA D 3 33  ? -32.556 -12.628 17.716 1   138.26 ? 274 ALA Q O   1 
ATOM   5055  C  CB  . ALA D 3 33  ? -34.512 -13.597 20.137 1   137.24 ? 274 ALA Q CB  1 
ATOM   5056  N  N   . SER D 3 34  ? -31.615 -14.32  18.941 1   146.87 ? 275 SER Q N   1 
ATOM   5057  C  CA  . SER D 3 34  ? -30.648 -14.824 17.928 1   150.92 ? 275 SER Q CA  1 
ATOM   5058  C  C   . SER D 3 34  ? -31.338 -15.805 16.968 1   150.87 ? 275 SER Q C   1 
ATOM   5059  O  O   . SER D 3 34  ? -31.101 -17.027 17.087 1   149.36 ? 275 SER Q O   1 
ATOM   5060  C  CB  . SER D 3 34  ? -29.44  -15.44  18.594 1   152.28 ? 275 SER Q CB  1 
ATOM   5061  O  OG  . SER D 3 34  ? -29.825 -16.476 19.484 1   157.95 ? 275 SER Q OG  1 
ATOM   5062  N  N   . GLY D 3 35  ? -32.168 -15.275 16.062 1   149.03 ? 276 GLY Q N   1 
ATOM   5063  C  CA  . GLY D 3 35  ? -32.675 -15.975 14.866 1   148.76 ? 276 GLY Q CA  1 
ATOM   5064  C  C   . GLY D 3 35  ? -31.848 -15.591 13.651 1   151.15 ? 276 GLY Q C   1 
ATOM   5065  O  O   . GLY D 3 35  ? -32.433 -15.069 12.68  1   149.47 ? 276 GLY Q O   1 
ATOM   5066  N  N   . VAL D 3 36  ? -30.534 -15.841 13.716 1   153.27 ? 277 VAL Q N   1 
ATOM   5067  C  CA  . VAL D 3 36  ? -29.495 -15.257 12.813 1   150.19 ? 277 VAL Q CA  1 
ATOM   5068  C  C   . VAL D 3 36  ? -28.858 -16.36  11.957 1   146.59 ? 277 VAL Q C   1 
ATOM   5069  O  O   . VAL D 3 36  ? -28.653 -17.475 12.477 1   138.75 ? 277 VAL Q O   1 
ATOM   5070  C  CB  . VAL D 3 36  ? -28.424 -14.501 13.623 1   146.92 ? 277 VAL Q CB  1 
ATOM   5071  C  CG1 . VAL D 3 36  ? -29.051 -13.325 14.39  0   162.83 ? 277 VAL Q CG1 1 
ATOM   5072  C  CG2 . VAL D 3 36  ? -27.626 -15.363 14.577 0   162.86 ? 277 VAL Q CG2 1 
ATOM   5073  N  N   . THR D 3 37  ? -28.548 -16.034 10.696 1   148.6  ? 278 THR Q N   1 
ATOM   5074  C  CA  . THR D 3 37  ? -27.854 -16.91  9.711  1   153.44 ? 278 THR Q CA  1 
ATOM   5075  C  C   . THR D 3 37  ? -26.774 -16.093 8.988  1   158.82 ? 278 THR Q C   1 
ATOM   5076  O  O   . THR D 3 37  ? -27.139 -15.099 8.325  1   167.35 ? 278 THR Q O   1 
ATOM   5077  C  CB  . THR D 3 37  ? -28.853 -17.524 8.721  1   147.2  ? 278 THR Q CB  1 
ATOM   5078  O  OG1 . THR D 3 37  ? -29.919 -18.114 9.443  0   163.14 ? 278 THR Q OG1 1 
ATOM   5079  C  CG2 . THR D 3 37  ? -28.211 -18.59  7.826  0   162.84 ? 278 THR Q CG2 1 
ATOM   5080  N  N   . PHE D 3 38  ? -25.504 -16.497 9.121  1   155.24 ? 279 PHE Q N   1 
ATOM   5081  C  CA  . PHE D 3 38  ? -24.312 -15.855 8.5    1   146.35 ? 279 PHE Q CA  1 
ATOM   5082  C  C   . PHE D 3 38  ? -23.992 -16.546 7.169  1   138.1  ? 279 PHE Q C   1 
ATOM   5083  O  O   . PHE D 3 38  ? -24.377 -17.72  6.992  1   135.28 ? 279 PHE Q O   1 
ATOM   5084  C  CB  . PHE D 3 38  ? -23.09  -15.95  9.419  1   149.2  ? 279 PHE Q CB  1 
ATOM   5085  C  CG  . PHE D 3 38  ? -23.237 -15.316 10.781 1   152.63 ? 279 PHE Q CG  1 
ATOM   5086  C  CD1 . PHE D 3 38  ? -23.886 -15.983 11.813 1   153.2  ? 279 PHE Q CD1 1 
ATOM   5087  C  CD2 . PHE D 3 38  ? -22.693 -14.066 11.046 1   154.09 ? 279 PHE Q CD2 1 
ATOM   5088  C  CE1 . PHE D 3 38  ? -24.007 -15.405 13.069 1   153.04 ? 279 PHE Q CE1 1 
ATOM   5089  C  CE2 . PHE D 3 38  ? -22.814 -13.489 12.303 1   154.45 ? 279 PHE Q CE2 1 
ATOM   5090  C  CZ  . PHE D 3 38  ? -23.47  -14.16  13.313 1   152.91 ? 279 PHE Q CZ  1 
ATOM   5091  N  N   . THR D 3 39  ? -23.297 -15.839 6.27   1   130.54 ? 280 THR Q N   1 
ATOM   5092  C  CA  . THR D 3 39  ? -22.761 -16.375 4.986  1   126.3  ? 280 THR Q CA  1 
ATOM   5093  C  C   . THR D 3 39  ? -21.356 -15.812 4.753  1   119.69 ? 280 THR Q C   1 
ATOM   5094  O  O   . THR D 3 39  ? -21.146 -14.622 5.058  1   111.64 ? 280 THR Q O   1 
ATOM   5095  C  CB  . THR D 3 39  ? -23.684 -16.057 3.802  1   128.57 ? 280 THR Q CB  1 
ATOM   5096  O  OG1 . THR D 3 39  ? -25.016 -16.428 4.158  1   131.5  ? 280 THR Q OG1 1 
ATOM   5097  C  CG2 . THR D 3 39  ? -23.292 -16.777 2.529  1   127.28 ? 280 THR Q CG2 1 
ATOM   5098  N  N   . TRP D 3 40  ? -20.453 -16.645 4.219  1   119.1  ? 281 TRP Q N   1 
ATOM   5099  C  CA  . TRP D 3 40  ? -19.027 -16.327 3.932  1   120.8  ? 281 TRP Q CA  1 
ATOM   5100  C  C   . TRP D 3 40  ? -18.746 -16.54  2.44   1   121.26 ? 281 TRP Q C   1 
ATOM   5101  O  O   . TRP D 3 40  ? -19.288 -17.511 1.874  1   116.2  ? 281 TRP Q O   1 
ATOM   5102  C  CB  . TRP D 3 40  ? -18.098 -17.189 4.796  1   121.21 ? 281 TRP Q CB  1 
ATOM   5103  C  CG  . TRP D 3 40  ? -18.315 -17.054 6.273  1   119.6  ? 281 TRP Q CG  1 
ATOM   5104  C  CD1 . TRP D 3 40  ? -19.245 -17.704 7.032  1   117.56 ? 281 TRP Q CD1 1 
ATOM   5105  C  CD2 . TRP D 3 40  ? -17.566 -16.226 7.181  1   118.15 ? 281 TRP Q CD2 1 
ATOM   5106  N  NE1 . TRP D 3 40  ? -19.134 -17.333 8.345  1   115.49 ? 281 TRP Q NE1 1 
ATOM   5107  C  CE2 . TRP D 3 40  ? -18.113 -16.428 8.469  1   117.69 ? 281 TRP Q CE2 1 
ATOM   5108  C  CE3 . TRP D 3 40  ? -16.493 -15.337 7.035  1   117.28 ? 281 TRP Q CE3 1 
ATOM   5109  C  CZ2 . TRP D 3 40  ? -17.621 -15.77  9.597  1   118.64 ? 281 TRP Q CZ2 1 
ATOM   5110  C  CZ3 . TRP D 3 40  ? -16.009 -14.686 8.15   1   118.53 ? 281 TRP Q CZ3 1 
ATOM   5111  C  CH2 . TRP D 3 40  ? -16.567 -14.901 9.413  1   118.56 ? 281 TRP Q CH2 1 
ATOM   5112  N  N   . THR D 3 41  ? -17.918 -15.676 1.84   1   127.4  ? 282 THR Q N   1 
ATOM   5113  C  CA  . THR D 3 41  ? -17.588 -15.684 0.386  1   132.65 ? 282 THR Q CA  1 
ATOM   5114  C  C   . THR D 3 41  ? -16.504 -16.726 0.095  1   140.42 ? 282 THR Q C   1 
ATOM   5115  O  O   . THR D 3 41  ? -16.818 -17.773 -0.469 1   142.48 ? 282 THR Q O   1 
ATOM   5116  C  CB  . THR D 3 41  ? -17.256 -14.273 -0.123 1   129.45 ? 282 THR Q CB  1 
ATOM   5117  O  OG1 . THR D 3 41  ? -18.429 -13.485 0.078  1   128.69 ? 282 THR Q OG1 1 
ATOM   5118  C  CG2 . THR D 3 41  ? -16.863 -14.219 -1.584 1   127.5  ? 282 THR Q CG2 1 
ATOM   5119  N  N   . PRO D 3 42  ? -15.219 -16.511 0.479  1   145.87 ? 283 PRO Q N   1 
ATOM   5120  C  CA  . PRO D 3 42  ? -14.09  -17.15  -0.208 1   147.27 ? 283 PRO Q CA  1 
ATOM   5121  C  C   . PRO D 3 42  ? -14.028 -18.683 -0.133 1   150    ? 283 PRO Q C   1 
ATOM   5122  O  O   . PRO D 3 42  ? -13.538 -19.283 -1.074 1   150.77 ? 283 PRO Q O   1 
ATOM   5123  C  CB  . PRO D 3 42  ? -12.851 -16.583 0.505  1   144.92 ? 283 PRO Q CB  1 
ATOM   5124  C  CG  . PRO D 3 42  ? -13.365 -15.345 1.192  1   146.02 ? 283 PRO Q CG  1 
ATOM   5125  C  CD  . PRO D 3 42  ? -14.763 -15.719 1.634  1   144.52 ? 283 PRO Q CD  1 
ATOM   5126  N  N   . SER D 3 43  ? -14.5   -19.265 0.975  1   153.22 ? 284 SER Q N   1 
ATOM   5127  C  CA  . SER D 3 43  ? -14.516 -20.729 1.236  1   156.96 ? 284 SER Q CA  1 
ATOM   5128  C  C   . SER D 3 43  ? -15.974 -21.215 1.284  1   157.75 ? 284 SER Q C   1 
ATOM   5129  O  O   . SER D 3 43  ? -16.699 -20.815 2.217  1   155.21 ? 284 SER Q O   1 
ATOM   5130  C  CB  . SER D 3 43  ? -13.732 -21.042 2.49   1   156.65 ? 284 SER Q CB  1 
ATOM   5131  O  OG  . SER D 3 43  ? -14.533 -20.933 3.657  1   160.39 ? 284 SER Q OG  1 
ATOM   5132  N  N   . SER D 3 44  ? -16.382 -22.023 0.295  1   161.04 ? 285 SER Q N   1 
ATOM   5133  C  CA  . SER D 3 44  ? -17.788 -22.43  0.02   1   163.78 ? 285 SER Q CA  1 
ATOM   5134  C  C   . SER D 3 44  ? -18.063 -23.831 0.584  1   166.74 ? 285 SER Q C   1 
ATOM   5135  O  O   . SER D 3 44  ? -17.375 -24.78  0.151  1   171.68 ? 285 SER Q O   1 
ATOM   5136  C  CB  . SER D 3 44  ? -18.076 -22.378 -1.46  1   160.98 ? 285 SER Q CB  1 
ATOM   5137  O  OG  . SER D 3 44  ? -17.098 -23.078 -2.2   0   164.57 ? 285 SER Q OG  1 
ATOM   5138  N  N   . GLY D 3 45  ? -19.037 -23.948 1.498  1   162.43 ? 286 GLY Q N   1 
ATOM   5139  C  CA  . GLY D 3 45  ? -19.431 -25.207 2.162  1   158.22 ? 286 GLY Q CA  1 
ATOM   5140  C  C   . GLY D 3 45  ? -18.285 -25.802 2.964  1   157.2  ? 286 GLY Q C   1 
ATOM   5141  O  O   . GLY D 3 45  ? -17.81  -26.894 2.587  1   157.25 ? 286 GLY Q O   1 
ATOM   5142  N  N   . LYS D 3 46  ? -17.85  -25.102 4.02   1   151.54 ? 287 LYS Q N   1 
ATOM   5143  C  CA  . LYS D 3 46  ? -16.644 -25.436 4.83   1   147.5  ? 287 LYS Q CA  1 
ATOM   5144  C  C   . LYS D 3 46  ? -16.972 -25.382 6.332  1   143.1  ? 287 LYS Q C   1 
ATOM   5145  O  O   . LYS D 3 46  ? -16.045 -25.116 7.128  1   139.04 ? 287 LYS Q O   1 
ATOM   5146  C  CB  . LYS D 3 46  ? -15.502 -24.478 4.472  1   145.97 ? 287 LYS Q CB  1 
ATOM   5147  C  CG  . LYS D 3 46  ? -15.167 -24.388 2.989  1   141.55 ? 287 LYS Q CG  1 
ATOM   5148  C  CD  . LYS D 3 46  ? -14.436 -25.493 2.4    0   152.23 ? 287 LYS Q CD  1 
ATOM   5149  C  CE  . LYS D 3 46  ? -13.924 -25.197 1.007  0   152.05 ? 287 LYS Q CE  1 
ATOM   5150  N  NZ  . LYS D 3 46  ? -13.104 -26.309 0.473  0   151.95 ? 287 LYS Q NZ  1 
ATOM   5151  N  N   . SER D 3 47  ? -18.229 -25.658 6.706  1   136.46 ? 288 SER Q N   1 
ATOM   5152  C  CA  . SER D 3 47  ? -18.732 -25.7   8.106  1   133.12 ? 288 SER Q CA  1 
ATOM   5153  C  C   . SER D 3 47  ? -18.364 -24.404 8.844  1   134.27 ? 288 SER Q C   1 
ATOM   5154  O  O   . SER D 3 47  ? -17.464 -24.447 9.709  1   133.56 ? 288 SER Q O   1 
ATOM   5155  C  CB  . SER D 3 47  ? -18.215 -26.922 8.827  1   128.67 ? 288 SER Q CB  1 
ATOM   5156  O  OG  . SER D 3 47  ? -16.827 -26.917 8.993  0   133.58 ? 288 SER Q OG  1 
ATOM   5157  N  N   . ALA D 3 48  ? -19.024 -23.296 8.488  1   134.24 ? 289 ALA Q N   1 
ATOM   5158  C  CA  . ALA D 3 48  ? -18.934 -21.985 9.175  1   134.4  ? 289 ALA Q CA  1 
ATOM   5159  C  C   . ALA D 3 48  ? -19.743 -22.054 10.479 1   137.07 ? 289 ALA Q C   1 
ATOM   5160  O  O   . ALA D 3 48  ? -20.988 -21.986 10.407 1   143.13 ? 289 ALA Q O   1 
ATOM   5161  C  CB  . ALA D 3 48  ? -19.421 -20.881 8.265  1   130.99 ? 289 ALA Q CB  1 
ATOM   5162  N  N   . VAL D 3 49  ? -19.059 -22.188 11.622 1   135.53 ? 290 VAL Q N   1 
ATOM   5163  C  CA  . VAL D 3 49  ? -19.66  -22.52  12.952 1   135.73 ? 290 VAL Q CA  1 
ATOM   5164  C  C   . VAL D 3 49  ? -20.145 -21.226 13.628 1   140.55 ? 290 VAL Q C   1 
ATOM   5165  O  O   . VAL D 3 49  ? -19.534 -20.165 13.386 1   142.23 ? 290 VAL Q O   1 
ATOM   5166  C  CB  . VAL D 3 49  ? -18.657 -23.298 13.832 1   131.15 ? 290 VAL Q CB  1 
ATOM   5167  C  CG1 . VAL D 3 49  ? -19.233 -23.675 15.19  1   130.47 ? 290 VAL Q CG1 1 
ATOM   5168  C  CG2 . VAL D 3 49  ? -18.131 -24.542 13.128 1   127.76 ? 290 VAL Q CG2 1 
ATOM   5169  N  N   . GLN D 3 50  ? -21.209 -21.326 14.438 1   142.88 ? 291 GLN Q N   1 
ATOM   5170  C  CA  . GLN D 3 50  ? -21.812 -20.224 15.242 1   141.45 ? 291 GLN Q CA  1 
ATOM   5171  C  C   . GLN D 3 50  ? -21.657 -20.54  16.736 1   142.57 ? 291 GLN Q C   1 
ATOM   5172  O  O   . GLN D 3 50  ? -21.235 -21.668 17.06  1   141.22 ? 291 GLN Q O   1 
ATOM   5173  C  CB  . GLN D 3 50  ? -23.294 -20.056 14.898 1   140.34 ? 291 GLN Q CB  1 
ATOM   5174  C  CG  . GLN D 3 50  ? -23.551 -19.636 13.458 1   138.66 ? 291 GLN Q CG  1 
ATOM   5175  C  CD  . GLN D 3 50  ? -25.035 -19.546 13.148 0   144.33 ? 291 GLN Q CD  1 
ATOM   5176  O  OE1 . GLN D 3 50  ? -25.894 -19.665 14.02  0   144.17 ? 291 GLN Q OE1 1 
ATOM   5177  N  NE2 . GLN D 3 50  ? -25.344 -19.324 11.88  0   144.25 ? 291 GLN Q NE2 1 
ATOM   5178  N  N   . GLY D 3 51  ? -22.002 -19.581 17.606 1   146.04 ? 292 GLY Q N   1 
ATOM   5179  C  CA  . GLY D 3 51  ? -21.953 -19.72  19.076 1   149.83 ? 292 GLY Q CA  1 
ATOM   5180  C  C   . GLY D 3 51  ? -23.185 -19.121 19.754 1   154.97 ? 292 GLY Q C   1 
ATOM   5181  O  O   . GLY D 3 51  ? -24.051 -18.569 19.075 1   152.39 ? 292 GLY Q O   1 
ATOM   5182  N  N   . PRO D 3 52  ? -23.309 -19.222 21.103 1   161.15 ? 293 PRO Q N   1 
ATOM   5183  C  CA  . PRO D 3 52  ? -24.424 -18.61  21.832 1   164.39 ? 293 PRO Q CA  1 
ATOM   5184  C  C   . PRO D 3 52  ? -24.372 -17.08  21.843 1   168.7  ? 293 PRO Q C   1 
ATOM   5185  O  O   . PRO D 3 52  ? -23.312 -16.496 21.621 1   175.98 ? 293 PRO Q O   1 
ATOM   5186  C  CB  . PRO D 3 52  ? -24.289 -19.145 23.271 1   161.25 ? 293 PRO Q CB  1 
ATOM   5187  C  CG  . PRO D 3 52  ? -23.31  -20.299 23.173 1   159.18 ? 293 PRO Q CG  1 
ATOM   5188  C  CD  . PRO D 3 52  ? -22.41  -19.962 22.003 1   159.76 ? 293 PRO Q CD  1 
ATOM   5189  N  N   . PRO D 3 53  ? -25.505 -16.385 22.117 1   164.88 ? 294 PRO Q N   1 
ATOM   5190  C  CA  . PRO D 3 53  ? -25.54  -14.92  22.103 1   160.54 ? 294 PRO Q CA  1 
ATOM   5191  C  C   . PRO D 3 53  ? -24.949 -14.304 23.384 1   158.48 ? 294 PRO Q C   1 
ATOM   5192  O  O   . PRO D 3 53  ? -25.677 -14.115 24.344 1   161.55 ? 294 PRO Q O   1 
ATOM   5193  C  CB  . PRO D 3 53  ? -27.041 -14.628 21.941 1   159.02 ? 294 PRO Q CB  1 
ATOM   5194  C  CG  . PRO D 3 53  ? -27.723 -15.775 22.658 1   159.66 ? 294 PRO Q CG  1 
ATOM   5195  C  CD  . PRO D 3 53  ? -26.815 -16.97  22.449 1   161.6  ? 294 PRO Q CD  1 
ATOM   5196  N  N   . GLU D 3 54  ? -23.644 -14.007 23.365 1   156    ? 295 GLU Q N   1 
ATOM   5197  C  CA  . GLU D 3 54  ? -22.899 -13.391 24.5   1   154.14 ? 295 GLU Q CA  1 
ATOM   5198  C  C   . GLU D 3 54  ? -23.287 -11.91  24.615 1   154.59 ? 295 GLU Q C   1 
ATOM   5199  O  O   . GLU D 3 54  ? -23.633 -11.312 23.579 1   161.57 ? 295 GLU Q O   1 
ATOM   5200  C  CB  . GLU D 3 54  ? -21.39  -13.553 24.304 1   152.08 ? 295 GLU Q CB  1 
ATOM   5201  C  CG  . GLU D 3 54  ? -20.93  -15.001 24.298 0   165.97 ? 295 GLU Q CG  1 
ATOM   5202  C  CD  . GLU D 3 54  ? -19.424 -15.204 24.239 0   165.78 ? 295 GLU Q CD  1 
ATOM   5203  O  OE1 . GLU D 3 54  ? -18.715 -14.28  23.788 0   165.6  ? 295 GLU Q OE1 1 
ATOM   5204  O  OE2 . GLU D 3 54  ? -18.962 -16.289 24.645 0   165.63 ? 295 GLU Q OE2 1 
ATOM   5205  N  N   . ARG D 3 55  ? -23.217 -11.35  25.829 1   153.5  ? 296 ARG Q N   1 
ATOM   5206  C  CA  . ARG D 3 55  ? -23.642 -9.958  26.158 1   151.69 ? 296 ARG Q CA  1 
ATOM   5207  C  C   . ARG D 3 55  ? -22.765 -8.952  25.401 1   147.76 ? 296 ARG Q C   1 
ATOM   5208  O  O   . ARG D 3 55  ? -21.566 -8.873  25.731 1   146.78 ? 296 ARG Q O   1 
ATOM   5209  C  CB  . ARG D 3 55  ? -23.574 -9.716  27.67  1   150.75 ? 296 ARG Q CB  1 
ATOM   5210  C  CG  . ARG D 3 55  ? -24.61  -10.492 28.472 1   149.74 ? 296 ARG Q CG  1 
ATOM   5211  C  CD  . ARG D 3 55  ? -25.98  -9.855  28.398 0   161.86 ? 296 ARG Q CD  1 
ATOM   5212  N  NE  . ARG D 3 55  ? -26.998 -10.596 29.129 0   161.67 ? 296 ARG Q NE  1 
ATOM   5213  C  CZ  . ARG D 3 55  ? -28.27  -10.226 29.223 0   161.5  ? 296 ARG Q CZ  1 
ATOM   5214  N  NH1 . ARG D 3 55  ? -28.682 -9.119  28.63  0   161.45 ? 296 ARG Q NH1 1 
ATOM   5215  N  NH2 . ARG D 3 55  ? -29.125 -10.963 29.909 0   161.42 ? 296 ARG Q NH2 1 
ATOM   5216  N  N   . GLY D 3 59  ? -24.296 -5.595  27.862 1   134.85 ? 300 GLY Q N   1 
ATOM   5217  C  CA  . GLY D 3 59  ? -25.681 -5.113  27.689 1   137.06 ? 300 GLY Q CA  1 
ATOM   5218  C  C   . GLY D 3 59  ? -26.451 -5.953  26.683 1   140.79 ? 300 GLY Q C   1 
ATOM   5219  O  O   . GLY D 3 59  ? -26.748 -7.122  27.004 1   137.07 ? 300 GLY Q O   1 
ATOM   5220  N  N   . CYS D 3 60  ? -26.757 -5.382  25.51  1   146.09 ? 301 CYS Q N   1 
ATOM   5221  C  CA  . CYS D 3 60  ? -27.441 -6.064  24.374 1   149.83 ? 301 CYS Q CA  1 
ATOM   5222  C  C   . CYS D 3 60  ? -26.547 -7.193  23.843 1   155.16 ? 301 CYS Q C   1 
ATOM   5223  O  O   . CYS D 3 60  ? -25.308 -7.026  23.853 1   159.27 ? 301 CYS Q O   1 
ATOM   5224  C  CB  . CYS D 3 60  ? -27.798 -5.082  23.262 1   149.99 ? 301 CYS Q CB  1 
ATOM   5225  S  SG  . CYS D 3 60  ? -26.46  -3.937  22.835 1   150.4  ? 301 CYS Q SG  1 
ATOM   5226  N  N   . TYR D 3 61  ? -27.158 -8.298  23.405 1   158.52 ? 302 TYR Q N   1 
ATOM   5227  C  CA  . TYR D 3 61  ? -26.471 -9.563  23.025 1   160.5  ? 302 TYR Q CA  1 
ATOM   5228  C  C   . TYR D 3 61  ? -25.729 -9.401  21.691 1   164.97 ? 302 TYR Q C   1 
ATOM   5229  O  O   . TYR D 3 61  ? -26.007 -8.444  20.938 1   172.65 ? 302 TYR Q O   1 
ATOM   5230  C  CB  . TYR D 3 61  ? -27.467 -10.725 22.953 1   158.34 ? 302 TYR Q CB  1 
ATOM   5231  C  CG  . TYR D 3 61  ? -27.965 -11.269 24.246 0   160.99 ? 302 TYR Q CG  1 
ATOM   5232  C  CD1 . TYR D 3 61  ? -27.104 -11.58  25.287 0   160.93 ? 302 TYR Q CD1 1 
ATOM   5233  C  CD2 . TYR D 3 61  ? -29.317 -11.498 24.439 0   160.92 ? 302 TYR Q CD2 1 
ATOM   5234  C  CE1 . TYR D 3 61  ? -27.573 -12.079 26.491 0   160.82 ? 302 TYR Q CE1 1 
ATOM   5235  C  CE2 . TYR D 3 61  ? -29.804 -11.996 25.636 0   160.82 ? 302 TYR Q CE2 1 
ATOM   5236  C  CZ  . TYR D 3 61  ? -28.929 -12.289 26.667 0   160.78 ? 302 TYR Q CZ  1 
ATOM   5237  O  OH  . TYR D 3 61  ? -29.4   -12.78  27.85  0   160.68 ? 302 TYR Q OH  1 
ATOM   5238  N  N   . SER D 3 62  ? -24.807 -10.333 21.423 1   164.33 ? 303 SER Q N   1 
ATOM   5239  C  CA  . SER D 3 62  ? -23.982 -10.434 20.188 1   157.87 ? 303 SER Q CA  1 
ATOM   5240  C  C   . SER D 3 62  ? -23.694 -11.91  19.883 1   156.07 ? 303 SER Q C   1 
ATOM   5241  O  O   . SER D 3 62  ? -23.231 -12.616 20.804 1   156.32 ? 303 SER Q O   1 
ATOM   5242  C  CB  . SER D 3 62  ? -22.705 -9.648  20.335 1   155    ? 303 SER Q CB  1 
ATOM   5243  O  OG  . SER D 3 62  ? -21.964 -9.657  19.125 1   156.04 ? 303 SER Q OG  1 
ATOM   5244  N  N   . VAL D 3 63  ? -23.958 -12.355 18.647 1   152.21 ? 304 VAL Q N   1 
ATOM   5245  C  CA  . VAL D 3 63  ? -23.764 -13.765 18.188 1   150.29 ? 304 VAL Q CA  1 
ATOM   5246  C  C   . VAL D 3 63  ? -22.435 -13.843 17.425 1   146.86 ? 304 VAL Q C   1 
ATOM   5247  O  O   . VAL D 3 63  ? -22.269 -13.071 16.457 1   147.66 ? 304 VAL Q O   1 
ATOM   5248  C  CB  . VAL D 3 63  ? -24.942 -14.26  17.322 1   150.89 ? 304 VAL Q CB  1 
ATOM   5249  C  CG1 . VAL D 3 63  ? -24.846 -15.753 17.033 1   151.04 ? 304 VAL Q CG1 1 
ATOM   5250  C  CG2 . VAL D 3 63  ? -26.291 -13.937 17.948 1   149.94 ? 304 VAL Q CG2 1 
ATOM   5251  N  N   . SER D 3 64  ? -21.541 -14.748 17.844 1   140.14 ? 305 SER Q N   1 
ATOM   5252  C  CA  . SER D 3 64  ? -20.182 -14.956 17.275 1   132.55 ? 305 SER Q CA  1 
ATOM   5253  C  C   . SER D 3 64  ? -20.22  -16.075 16.226 1   128.54 ? 305 SER Q C   1 
ATOM   5254  O  O   . SER D 3 64  ? -20.739 -17.164 16.55  1   129.13 ? 305 SER Q O   1 
ATOM   5255  C  CB  . SER D 3 64  ? -19.184 -15.264 18.361 1   129.02 ? 305 SER Q CB  1 
ATOM   5256  O  OG  . SER D 3 64  ? -19.575 -16.393 19.113 0   130.91 ? 305 SER Q OG  1 
ATOM   5257  N  N   . SER D 3 65  ? -19.689 -15.808 15.026 1   126.49 ? 306 SER Q N   1 
ATOM   5258  C  CA  . SER D 3 65  ? -19.547 -16.768 13.896 1   125.42 ? 306 SER Q CA  1 
ATOM   5259  C  C   . SER D 3 65  ? -18.063 -16.951 13.557 1   124.75 ? 306 SER Q C   1 
ATOM   5260  O  O   . SER D 3 65  ? -17.39  -15.927 13.32  1   129.06 ? 306 SER Q O   1 
ATOM   5261  C  CB  . SER D 3 65  ? -20.319 -16.298 12.691 1   124.85 ? 306 SER Q CB  1 
ATOM   5262  O  OG  . SER D 3 65  ? -20.077 -17.141 11.572 1   122    ? 306 SER Q OG  1 
ATOM   5263  N  N   . VAL D 3 66  ? -17.589 -18.203 13.508 1   121.48 ? 307 VAL Q N   1 
ATOM   5264  C  CA  . VAL D 3 66  ? -16.173 -18.57  13.19  1   117.91 ? 307 VAL Q CA  1 
ATOM   5265  C  C   . VAL D 3 66  ? -16.144 -19.382 11.888 1   113.74 ? 307 VAL Q C   1 
ATOM   5266  O  O   . VAL D 3 66  ? -17.192 -19.944 11.506 1   112.72 ? 307 VAL Q O   1 
ATOM   5267  C  CB  . VAL D 3 66  ? -15.481 -19.318 14.352 1   118.69 ? 307 VAL Q CB  1 
ATOM   5268  C  CG1 . VAL D 3 66  ? -15.402 -18.457 15.604 1   118.55 ? 307 VAL Q CG1 1 
ATOM   5269  C  CG2 . VAL D 3 66  ? -16.126 -20.66  14.673 1   119.18 ? 307 VAL Q CG2 1 
ATOM   5270  N  N   . LEU D 3 67  ? -14.975 -19.427 11.243 1   110.53 ? 308 LEU Q N   1 
ATOM   5271  C  CA  . LEU D 3 67  ? -14.72  -20.127 9.954  1   107.93 ? 308 LEU Q CA  1 
ATOM   5272  C  C   . LEU D 3 67  ? -13.309 -20.714 9.987  1   107.92 ? 308 LEU Q C   1 
ATOM   5273  O  O   . LEU D 3 67  ? -12.343 -19.956 10.039 1   109.86 ? 308 LEU Q O   1 
ATOM   5274  C  CB  . LEU D 3 67  ? -14.88  -19.112 8.816  1   105.64 ? 308 LEU Q CB  1 
ATOM   5275  C  CG  . LEU D 3 67  ? -14.681 -19.652 7.4    1   105.16 ? 308 LEU Q CG  1 
ATOM   5276  C  CD1 . LEU D 3 67  ? -15.82  -20.579 7.006  1   107.07 ? 308 LEU Q CD1 1 
ATOM   5277  C  CD2 . LEU D 3 67  ? -14.554 -18.51  6.402  1   104.69 ? 308 LEU Q CD2 1 
ATOM   5278  N  N   . PRO D 3 68  ? -13.136 -22.061 9.975  1   106.58 ? 309 PRO Q N   1 
ATOM   5279  C  CA  . PRO D 3 68  ? -11.806 -22.673 10.04  1   103.38 ? 309 PRO Q CA  1 
ATOM   5280  C  C   . PRO D 3 68  ? -11.085 -22.799 8.686  1   98.28  ? 309 PRO Q C   1 
ATOM   5281  O  O   . PRO D 3 68  ? -11.737 -22.718 7.657  1   95.51  ? 309 PRO Q O   1 
ATOM   5282  C  CB  . PRO D 3 68  ? -12.125 -24.065 10.606 1   104.89 ? 309 PRO Q CB  1 
ATOM   5283  C  CG  . PRO D 3 68  ? -13.471 -24.399 10.003 1   106.96 ? 309 PRO Q CG  1 
ATOM   5284  C  CD  . PRO D 3 68  ? -14.205 -23.074 9.929  1   107.32 ? 309 PRO Q CD  1 
ATOM   5285  N  N   . GLY D 3 69  ? -9.76   -22.993 8.732  1   94.57  ? 310 GLY Q N   1 
ATOM   5286  C  CA  . GLY D 3 69  ? -8.89   -23.271 7.571  1   92.47  ? 310 GLY Q CA  1 
ATOM   5287  C  C   . GLY D 3 69  ? -8.815  -22.105 6.598  1   89.95  ? 310 GLY Q C   1 
ATOM   5288  O  O   . GLY D 3 69  ? -8.83   -22.36  5.379  1   86.83  ? 310 GLY Q O   1 
ATOM   5289  N  N   . CYS D 3 70  ? -8.708  -20.875 7.111  1   90.49  ? 311 CYS Q N   1 
ATOM   5290  C  CA  . CYS D 3 70  ? -8.673  -19.614 6.319  1   90.44  ? 311 CYS Q CA  1 
ATOM   5291  C  C   . CYS D 3 70  ? -7.229  -19.182 6.024  1   88.22  ? 311 CYS Q C   1 
ATOM   5292  O  O   . CYS D 3 70  ? -7.07   -18.136 5.37   1   89.1   ? 311 CYS Q O   1 
ATOM   5293  C  CB  . CYS D 3 70  ? -9.384  -18.488 7.06   1   92.45  ? 311 CYS Q CB  1 
ATOM   5294  S  SG  . CYS D 3 70  ? -11.051 -18.933 7.611  1   97.6   ? 311 CYS Q SG  1 
ATOM   5295  N  N   . ALA D 3 71  ? -6.227  -19.96  6.456  1   85.36  ? 312 ALA Q N   1 
ATOM   5296  C  CA  . ALA D 3 71  ? -4.795  -19.576 6.492  1   83.05  ? 312 ALA Q CA  1 
ATOM   5297  C  C   . ALA D 3 71  ? -4.281  -19.257 5.083  1   84.13  ? 312 ALA Q C   1 
ATOM   5298  O  O   . ALA D 3 71  ? -3.779  -18.132 4.886  1   79.98  ? 312 ALA Q O   1 
ATOM   5299  C  CB  . ALA D 3 71  ? -3.978  -20.671 7.129  1   82.38  ? 312 ALA Q CB  1 
ATOM   5300  N  N   . GLU D 3 72  ? -4.396  -20.207 4.148  1   89.03  ? 313 GLU Q N   1 
ATOM   5301  C  CA  . GLU D 3 72  ? -3.799  -20.099 2.786  1   91     ? 313 GLU Q CA  1 
ATOM   5302  C  C   . GLU D 3 72  ? -4.439  -18.925 2.04   1   90.17  ? 313 GLU Q C   1 
ATOM   5303  O  O   . GLU D 3 72  ? -3.704  -18.088 1.518  1   91.66  ? 313 GLU Q O   1 
ATOM   5304  C  CB  . GLU D 3 72  ? -3.874  -21.429 2.024  1   91.72  ? 313 GLU Q CB  1 
ATOM   5305  C  CG  . GLU D 3 72  ? -3.25   -21.388 0.636  1   91.4   ? 313 GLU Q CG  1 
ATOM   5306  C  CD  . GLU D 3 72  ? -1.732  -21.302 0.607  1   94.37  ? 313 GLU Q CD  1 
ATOM   5307  O  OE1 . GLU D 3 72  ? -1.088  -22.366 0.64   1   99.31  ? 313 GLU Q OE1 1 
ATOM   5308  O  OE2 . GLU D 3 72  ? -1.193  -20.174 0.553  1   95.73  ? 313 GLU Q OE2 1 
ATOM   5309  N  N   . PRO D 3 73  ? -5.79   -18.8   1.955  1   89.66  ? 314 PRO Q N   1 
ATOM   5310  C  CA  . PRO D 3 73  ? -6.408  -17.642 1.298  1   87.4   ? 314 PRO Q CA  1 
ATOM   5311  C  C   . PRO D 3 73  ? -6.041  -16.291 1.94   1   84.52  ? 314 PRO Q C   1 
ATOM   5312  O  O   . PRO D 3 73  ? -5.76   -15.356 1.204  1   81.99  ? 314 PRO Q O   1 
ATOM   5313  C  CB  . PRO D 3 73  ? -7.92   -17.885 1.423  1   88.17  ? 314 PRO Q CB  1 
ATOM   5314  C  CG  . PRO D 3 73  ? -8.053  -19.372 1.667  1   89.77  ? 314 PRO Q CG  1 
ATOM   5315  C  CD  . PRO D 3 73  ? -6.801  -19.765 2.422  1   89.01  ? 314 PRO Q CD  1 
ATOM   5316  N  N   . TRP D 3 74  ? -6.051  -16.224 3.277  1   80.27  ? 315 TRP Q N   1 
ATOM   5317  C  CA  . TRP D 3 74  ? -5.666  -15.022 4.066  1   77.62  ? 315 TRP Q CA  1 
ATOM   5318  C  C   . TRP D 3 74  ? -4.251  -14.584 3.669  1   78.79  ? 315 TRP Q C   1 
ATOM   5319  O  O   . TRP D 3 74  ? -4.093  -13.42  3.253  1   78.95  ? 315 TRP Q O   1 
ATOM   5320  C  CB  . TRP D 3 74  ? -5.778  -15.288 5.574  1   74.03  ? 315 TRP Q CB  1 
ATOM   5321  C  CG  . TRP D 3 74  ? -5.286  -14.154 6.417  1   71.39  ? 315 TRP Q CG  1 
ATOM   5322  C  CD1 . TRP D 3 74  ? -4.031  -13.996 6.928  1   70.55  ? 315 TRP Q CD1 1 
ATOM   5323  C  CD2 . TRP D 3 74  ? -6.033  -12.995 6.824  1   71.81  ? 315 TRP Q CD2 1 
ATOM   5324  N  NE1 . TRP D 3 74  ? -3.946  -12.823 7.626  1   72.44  ? 315 TRP Q NE1 1 
ATOM   5325  C  CE2 . TRP D 3 74  ? -5.158  -12.187 7.582  1   72.74  ? 315 TRP Q CE2 1 
ATOM   5326  C  CE3 . TRP D 3 74  ? -7.348  -12.56  6.623  1   71.26  ? 315 TRP Q CE3 1 
ATOM   5327  C  CZ2 . TRP D 3 74  ? -5.562  -10.973 8.14   1   72.08  ? 315 TRP Q CZ2 1 
ATOM   5328  C  CZ3 . TRP D 3 74  ? -7.746  -11.361 7.176  1   70.67  ? 315 TRP Q CZ3 1 
ATOM   5329  C  CH2 . TRP D 3 74  ? -6.864  -10.581 7.926  1   71.53  ? 315 TRP Q CH2 1 
ATOM   5330  N  N   . ASN D 3 75  ? -3.279  -15.498 3.765  1   80.87  ? 316 ASN Q N   1 
ATOM   5331  C  CA  . ASN D 3 75  ? -1.841  -15.25  3.465  1   82.55  ? 316 ASN Q CA  1 
ATOM   5332  C  C   . ASN D 3 75  ? -1.647  -14.98  1.964  1   86.2   ? 316 ASN Q C   1 
ATOM   5333  O  O   . ASN D 3 75  ? -0.675  -14.269 1.626  1   84.14  ? 316 ASN Q O   1 
ATOM   5334  C  CB  . ASN D 3 75  ? -0.952  -16.402 3.949  1   80.87  ? 316 ASN Q CB  1 
ATOM   5335  C  CG  . ASN D 3 75  ? -0.924  -16.548 5.458  1   79.82  ? 316 ASN Q CG  1 
ATOM   5336  O  OD1 . ASN D 3 75  ? -0.939  -15.557 6.184  1   79.11  ? 316 ASN Q OD1 1 
ATOM   5337  N  ND2 . ASN D 3 75  ? -0.867  -17.778 5.946  1   79.95  ? 316 ASN Q ND2 1 
ATOM   5338  N  N   . HIS D 3 76  ? -2.52   -15.522 1.1    1   89.96  ? 317 HIS Q N   1 
ATOM   5339  C  CA  . HIS D 3 76  ? -2.559  -15.235 -0.365 1   91.69  ? 317 HIS Q CA  1 
ATOM   5340  C  C   . HIS D 3 76  ? -3.03   -13.791 -0.615 1   90.13  ? 317 HIS Q C   1 
ATOM   5341  O  O   . HIS D 3 76  ? -2.668  -13.232 -1.677 1   84.93  ? 317 HIS Q O   1 
ATOM   5342  C  CB  . HIS D 3 76  ? -3.426  -16.261 -1.129 1   90.65  ? 317 HIS Q CB  1 
ATOM   5343  C  CG  . HIS D 3 76  ? -2.718  -17.515 -1.537 1   89.42  ? 317 HIS Q CG  1 
ATOM   5344  N  ND1 . HIS D 3 76  ? -3.403  -18.672 -1.855 1   87.95  ? 317 HIS Q ND1 1 
ATOM   5345  C  CD2 . HIS D 3 76  ? -1.406  -17.806 -1.69  1   90.45  ? 317 HIS Q CD2 1 
ATOM   5346  C  CE1 . HIS D 3 76  ? -2.547  -19.614 -2.194 1   86.72  ? 317 HIS Q CE1 1 
ATOM   5347  N  NE2 . HIS D 3 76  ? -1.314  -19.11  -2.095 1   87.15  ? 317 HIS Q NE2 1 
ATOM   5348  N  N   . GLY D 3 77  ? -3.811  -13.217 0.312  1   87.38  ? 318 GLY Q N   1 
ATOM   5349  C  CA  . GLY D 3 77  ? -4.266  -11.813 0.285  1   86.35  ? 318 GLY Q CA  1 
ATOM   5350  C  C   . GLY D 3 77  ? -5.717  -11.675 -0.15  1   84.62  ? 318 GLY Q C   1 
ATOM   5351  O  O   . GLY D 3 77  ? -6.189  -10.526 -0.233 1   82.77  ? 318 GLY Q O   1 
ATOM   5352  N  N   . LYS D 3 78  ? -6.406  -12.794 -0.411 1   85.46  ? 319 LYS Q N   1 
ATOM   5353  C  CA  . LYS D 3 78  ? -7.839  -12.835 -0.816 1   83.93  ? 319 LYS Q CA  1 
ATOM   5354  C  C   . LYS D 3 78  ? -8.689  -12.145 0.26   1   78.4   ? 319 LYS Q C   1 
ATOM   5355  O  O   . LYS D 3 78  ? -8.304  -12.203 1.447  1   76.12  ? 319 LYS Q O   1 
ATOM   5356  C  CB  . LYS D 3 78  ? -8.297  -14.28  -1.05  1   83.64  ? 319 LYS Q CB  1 
ATOM   5357  C  CG  . LYS D 3 78  ? -7.701  -14.959 -2.279 1   82.27  ? 319 LYS Q CG  1 
ATOM   5358  C  CD  . LYS D 3 78  ? -8.177  -16.363 -2.499 0   84.66  ? 319 LYS Q CD  1 
ATOM   5359  C  CE  . LYS D 3 78  ? -7.602  -16.998 -3.747 0   84.63  ? 319 LYS Q CE  1 
ATOM   5360  N  NZ  . LYS D 3 78  ? -8.058  -18.398 -3.91  0   84.59  ? 319 LYS Q NZ  1 
ATOM   5361  N  N   . THR D 3 79  ? -9.788  -11.504 -0.153 1   75.71  ? 320 THR Q N   1 
ATOM   5362  C  CA  . THR D 3 79  ? -10.681 -10.689 0.716  1   76.11  ? 320 THR Q CA  1 
ATOM   5363  C  C   . THR D 3 79  ? -11.838 -11.554 1.224  1   74.27  ? 320 THR Q C   1 
ATOM   5364  O  O   . THR D 3 79  ? -12.482 -12.216 0.396  1   73.4   ? 320 THR Q O   1 
ATOM   5365  C  CB  . THR D 3 79  ? -11.198 -9.45   -0.026 1   74.33  ? 320 THR Q CB  1 
ATOM   5366  O  OG1 . THR D 3 79  ? -10.07  -8.712  -0.499 1   73.69  ? 320 THR Q OG1 1 
ATOM   5367  C  CG2 . THR D 3 79  ? -12.052 -8.553  0.842  1   74.44  ? 320 THR Q CG2 1 
ATOM   5368  N  N   . PHE D 3 80  ? -12.093 -11.517 2.534  1   77.52  ? 321 PHE Q N   1 
ATOM   5369  C  CA  . PHE D 3 80  ? -13.201 -12.231 3.219  1   81.6   ? 321 PHE Q CA  1 
ATOM   5370  C  C   . PHE D 3 80  ? -14.365 -11.259 3.438  1   82.11  ? 321 PHE Q C   1 
ATOM   5371  O  O   . PHE D 3 80  ? -14.14  -10.178 4.018  1   81.01  ? 321 PHE Q O   1 
ATOM   5372  C  CB  . PHE D 3 80  ? -12.72  -12.838 4.54   1   84.28  ? 321 PHE Q CB  1 
ATOM   5373  C  CG  . PHE D 3 80  ? -11.757 -13.988 4.382  1   86.14  ? 321 PHE Q CG  1 
ATOM   5374  C  CD1 . PHE D 3 80  ? -10.438 -13.766 4.01   1   86.94  ? 321 PHE Q CD1 1 
ATOM   5375  C  CD2 . PHE D 3 80  ? -12.171 -15.296 4.595  1   87.79  ? 321 PHE Q CD2 1 
ATOM   5376  C  CE1 . PHE D 3 80  ? -9.556  -14.825 3.859  1   89.78  ? 321 PHE Q CE1 1 
ATOM   5377  C  CE2 . PHE D 3 80  ? -11.287 -16.354 4.445  1   89.38  ? 321 PHE Q CE2 1 
ATOM   5378  C  CZ  . PHE D 3 80  ? -9.982  -16.117 4.078  1   90.4   ? 321 PHE Q CZ  1 
ATOM   5379  N  N   . THR D 3 81  ? -15.557 -11.632 2.96   1   85.45  ? 322 THR Q N   1 
ATOM   5380  C  CA  . THR D 3 81  ? -16.848 -10.932 3.198  1   87.2   ? 322 THR Q CA  1 
ATOM   5381  C  C   . THR D 3 81  ? -17.702 -11.821 4.107  1   88.64  ? 322 THR Q C   1 
ATOM   5382  O  O   . THR D 3 81  ? -17.729 -13.044 3.863  1   86.11  ? 322 THR Q O   1 
ATOM   5383  C  CB  . THR D 3 81  ? -17.546 -10.598 1.872  1   86.87  ? 322 THR Q CB  1 
ATOM   5384  O  OG1 . THR D 3 81  ? -16.652 -9.827  1.068  1   86.33  ? 322 THR Q OG1 1 
ATOM   5385  C  CG2 . THR D 3 81  ? -18.839 -9.832  2.052  1   86.66  ? 322 THR Q CG2 1 
ATOM   5386  N  N   . CYS D 3 82  ? -18.355 -11.226 5.112  1   94.04  ? 323 CYS Q N   1 
ATOM   5387  C  CA  . CYS D 3 82  ? -19.221 -11.916 6.107  1   102.6  ? 323 CYS Q CA  1 
ATOM   5388  C  C   . CYS D 3 82  ? -20.561 -11.178 6.238  1   107.38 ? 323 CYS Q C   1 
ATOM   5389  O  O   . CYS D 3 82  ? -20.674 -10.295 7.115  1   108.53 ? 323 CYS Q O   1 
ATOM   5390  C  CB  . CYS D 3 82  ? -18.522 -12.026 7.458  1   106.01 ? 323 CYS Q CB  1 
ATOM   5391  S  SG  . CYS D 3 82  ? -19.526 -12.861 8.716  1   113.73 ? 323 CYS Q SG  1 
ATOM   5392  N  N   . THR D 3 83  ? -21.533 -11.533 5.389  1   112.12 ? 324 THR Q N   1 
ATOM   5393  C  CA  . THR D 3 83  ? -22.928 -11.014 5.414  1   111.86 ? 324 THR Q CA  1 
ATOM   5394  C  C   . THR D 3 83  ? -23.717 -11.797 6.469  1   113.04 ? 324 THR Q C   1 
ATOM   5395  O  O   . THR D 3 83  ? -23.655 -13.046 6.443  1   108.06 ? 324 THR Q O   1 
ATOM   5396  C  CB  . THR D 3 83  ? -23.576 -11.083 4.025  1   109.8  ? 324 THR Q CB  1 
ATOM   5397  O  OG1 . THR D 3 83  ? -23.429 -12.413 3.529  1   112.42 ? 324 THR Q OG1 1 
ATOM   5398  C  CG2 . THR D 3 83  ? -22.968 -10.11  3.039  1   107.47 ? 324 THR Q CG2 1 
ATOM   5399  N  N   . ALA D 3 84  ? -24.413 -11.083 7.361  1   120.43 ? 325 ALA Q N   1 
ATOM   5400  C  CA  . ALA D 3 84  ? -25.124 -11.634 8.54   1   129.61 ? 325 ALA Q CA  1 
ATOM   5401  C  C   . ALA D 3 84  ? -26.582 -11.154 8.546  1   136.34 ? 325 ALA Q C   1 
ATOM   5402  O  O   . ALA D 3 84  ? -26.804 -9.935  8.706  1   134.2  ? 325 ALA Q O   1 
ATOM   5403  C  CB  . ALA D 3 84  ? -24.404 -11.223 9.801  1   131.75 ? 325 ALA Q CB  1 
ATOM   5404  N  N   . ALA D 3 85  ? -27.529 -12.085 8.373  1   142.86 ? 326 ALA Q N   1 
ATOM   5405  C  CA  . ALA D 3 85  ? -28.991 -11.854 8.468  1   146.44 ? 326 ALA Q CA  1 
ATOM   5406  C  C   . ALA D 3 85  ? -29.405 -11.86  9.944  1   151.04 ? 326 ALA Q C   1 
ATOM   5407  O  O   . ALA D 3 85  ? -28.987 -12.792 10.662 1   150.11 ? 326 ALA Q O   1 
ATOM   5408  C  CB  . ALA D 3 85  ? -29.74  -12.905 7.683  1   144.1  ? 326 ALA Q CB  1 
ATOM   5409  N  N   . TYR D 3 86  ? -30.191 -10.862 10.371 1   156.33 ? 327 TYR Q N   1 
ATOM   5410  C  CA  . TYR D 3 86  ? -30.69  -10.698 11.765 1   157.01 ? 327 TYR Q CA  1 
ATOM   5411  C  C   . TYR D 3 86  ? -32.167 -10.297 11.734 1   154.5  ? 327 TYR Q C   1 
ATOM   5412  O  O   . TYR D 3 86  ? -32.558 -9.489  10.893 1   149.41 ? 327 TYR Q O   1 
ATOM   5413  C  CB  . TYR D 3 86  ? -29.807 -9.72   12.549 1   158.44 ? 327 TYR Q CB  1 
ATOM   5414  C  CG  . TYR D 3 86  ? -29.803 -8.284  12.078 1   159.6  ? 327 TYR Q CG  1 
ATOM   5415  C  CD1 . TYR D 3 86  ? -29.19  -7.916  10.887 1   160.76 ? 327 TYR Q CD1 1 
ATOM   5416  C  CD2 . TYR D 3 86  ? -30.369 -7.277  12.848 1   158.34 ? 327 TYR Q CD2 1 
ATOM   5417  C  CE1 . TYR D 3 86  ? -29.17  -6.596  10.459 1   159.81 ? 327 TYR Q CE1 1 
ATOM   5418  C  CE2 . TYR D 3 86  ? -30.354 -5.952  12.436 1   157.2  ? 327 TYR Q CE2 1 
ATOM   5419  C  CZ  . TYR D 3 86  ? -29.751 -5.609  11.238 1   157.63 ? 327 TYR Q CZ  1 
ATOM   5420  O  OH  . TYR D 3 86  ? -29.734 -4.309  10.824 1   154.33 ? 327 TYR Q OH  1 
ATOM   5421  N  N   . PRO D 3 87  ? -33.031 -10.853 12.623 1   155.13 ? 328 PRO Q N   1 
ATOM   5422  C  CA  . PRO D 3 87  ? -34.474 -10.585 12.582 1   153.84 ? 328 PRO Q CA  1 
ATOM   5423  C  C   . PRO D 3 87  ? -34.909 -9.112  12.687 1   151.16 ? 328 PRO Q C   1 
ATOM   5424  O  O   . PRO D 3 87  ? -35.888 -8.77   12.045 1   154.83 ? 328 PRO Q O   1 
ATOM   5425  C  CB  . PRO D 3 87  ? -35.024 -11.334 13.809 1   154.1  ? 328 PRO Q CB  1 
ATOM   5426  C  CG  . PRO D 3 87  ? -34.01  -12.419 14.073 1   154.02 ? 328 PRO Q CG  1 
ATOM   5427  C  CD  . PRO D 3 87  ? -32.682 -11.798 13.699 1   154.69 ? 328 PRO Q CD  1 
ATOM   5428  N  N   . GLU D 3 88  ? -34.196 -8.301  13.483 1   142.44 ? 329 GLU Q N   1 
ATOM   5429  C  CA  . GLU D 3 88  ? -34.544 -6.882  13.802 1   135.75 ? 329 GLU Q CA  1 
ATOM   5430  C  C   . GLU D 3 88  ? -34.75  -6.064  12.517 1   135.44 ? 329 GLU Q C   1 
ATOM   5431  O  O   . GLU D 3 88  ? -35.654 -5.206  12.519 1   137.38 ? 329 GLU Q O   1 
ATOM   5432  C  CB  . GLU D 3 88  ? -33.483 -6.218  14.69  1   130.65 ? 329 GLU Q CB  1 
ATOM   5433  C  CG  . GLU D 3 88  ? -34.008 -5.806  16.055 1   126.53 ? 329 GLU Q CG  1 
ATOM   5434  C  CD  . GLU D 3 88  ? -33.014 -5.037  16.911 1   121.48 ? 329 GLU Q CD  1 
ATOM   5435  O  OE1 . GLU D 3 88  ? -31.934 -5.585  17.197 1   118.02 ? 329 GLU Q OE1 1 
ATOM   5436  O  OE2 . GLU D 3 88  ? -33.318 -3.886  17.28  1   116.2  ? 329 GLU Q OE2 1 
ATOM   5437  N  N   . SER D 3 89  ? -33.939 -6.306  11.479 1   134.48 ? 330 SER Q N   1 
ATOM   5438  C  CA  . SER D 3 89  ? -34.046 -5.68   10.132 1   132.3  ? 330 SER Q CA  1 
ATOM   5439  C  C   . SER D 3 89  ? -34.543 -6.712  9.109  1   135.09 ? 330 SER Q C   1 
ATOM   5440  O  O   . SER D 3 89  ? -34.619 -7.911  9.455  1   133.65 ? 330 SER Q O   1 
ATOM   5441  C  CB  . SER D 3 89  ? -32.728 -5.081  9.714  1   126.44 ? 330 SER Q CB  1 
ATOM   5442  O  OG  . SER D 3 89  ? -32.883 -4.256  8.57   1   121.63 ? 330 SER Q OG  1 
ATOM   5443  N  N   . LYS D 3 90  ? -34.881 -6.25   7.9    1   137.27 ? 331 LYS Q N   1 
ATOM   5444  C  CA  . LYS D 3 90  ? -35.312 -7.097  6.753  1   137.99 ? 331 LYS Q CA  1 
ATOM   5445  C  C   . LYS D 3 90  ? -34.072 -7.579  5.99   1   139.44 ? 331 LYS Q C   1 
ATOM   5446  O  O   . LYS D 3 90  ? -33.928 -8.809  5.818  1   131.2  ? 331 LYS Q O   1 
ATOM   5447  C  CB  . LYS D 3 90  ? -36.256 -6.319  5.829  1   137.68 ? 331 LYS Q CB  1 
ATOM   5448  C  CG  . LYS D 3 90  ? -37.602 -5.95   6.439  1   136.57 ? 331 LYS Q CG  1 
ATOM   5449  C  CD  . LYS D 3 90  ? -38.574 -5.354  5.443  0   141.33 ? 331 LYS Q CD  1 
ATOM   5450  C  CE  . LYS D 3 90  ? -39.94  -5.083  6.037  0   141.25 ? 331 LYS Q CE  1 
ATOM   5451  N  NZ  . LYS D 3 90  ? -40.868 -4.508  5.035  0   141.16 ? 331 LYS Q NZ  1 
ATOM   5452  N  N   . THR D 3 91  ? -33.22  -6.639  5.557  1   142.18 ? 332 THR Q N   1 
ATOM   5453  C  CA  . THR D 3 91  ? -31.968 -6.88   4.783  1   141.14 ? 332 THR Q CA  1 
ATOM   5454  C  C   . THR D 3 91  ? -30.765 -6.874  5.73   1   143.83 ? 332 THR Q C   1 
ATOM   5455  O  O   . THR D 3 91  ? -30.791 -6.193  6.755  1   143.85 ? 332 THR Q O   1 
ATOM   5456  C  CB  . THR D 3 91  ? -31.819 -5.851  3.653  1   135.89 ? 332 THR Q CB  1 
ATOM   5457  O  OG1 . THR D 3 91  ? -31.967 -4.544  4.21   1   134.55 ? 332 THR Q OG1 1 
ATOM   5458  C  CG2 . THR D 3 91  ? -32.828 -6.047  2.543  1   131.29 ? 332 THR Q CG2 1 
ATOM   5459  N  N   . PRO D 3 92  ? -29.671 -7.615  5.417  1   144.57 ? 333 PRO Q N   1 
ATOM   5460  C  CA  . PRO D 3 92  ? -28.546 -7.775  6.342  1   142.49 ? 333 PRO Q CA  1 
ATOM   5461  C  C   . PRO D 3 92  ? -27.501 -6.648  6.287  1   143.03 ? 333 PRO Q C   1 
ATOM   5462  O  O   . PRO D 3 92  ? -27.672 -5.721  5.509  1   138.9  ? 333 PRO Q O   1 
ATOM   5463  C  CB  . PRO D 3 92  ? -27.933 -9.093  5.847  1   141.7  ? 333 PRO Q CB  1 
ATOM   5464  C  CG  . PRO D 3 92  ? -28.109 -9.025  4.347  1   140.95 ? 333 PRO Q CG  1 
ATOM   5465  C  CD  . PRO D 3 92  ? -29.444 -8.336  4.151  1   143    ? 333 PRO Q CD  1 
ATOM   5466  N  N   . LEU D 3 93  ? -26.456 -6.766  7.117  1   142.55 ? 334 LEU Q N   1 
ATOM   5467  C  CA  . LEU D 3 93  ? -25.26  -5.875  7.147  1   139.67 ? 334 LEU Q CA  1 
ATOM   5468  C  C   . LEU D 3 93  ? -24.082 -6.575  6.453  1   135.35 ? 334 LEU Q C   1 
ATOM   5469  O  O   . LEU D 3 93  ? -24.093 -7.824  6.372  1   131.19 ? 334 LEU Q O   1 
ATOM   5470  C  CB  . LEU D 3 93  ? -24.913 -5.535  8.601  1   138.77 ? 334 LEU Q CB  1 
ATOM   5471  C  CG  . LEU D 3 93  ? -25.927 -4.671  9.349  1   138.1  ? 334 LEU Q CG  1 
ATOM   5472  C  CD1 . LEU D 3 93  ? -25.654 -4.69   10.846 1   137.14 ? 334 LEU Q CD1 1 
ATOM   5473  C  CD2 . LEU D 3 93  ? -25.923 -3.24   8.829  1   137.48 ? 334 LEU Q CD2 1 
ATOM   5474  N  N   . THR D 3 94  ? -23.105 -5.789  5.986  1   129.17 ? 335 THR Q N   1 
ATOM   5475  C  CA  . THR D 3 94  ? -21.9   -6.243  5.237  1   125.98 ? 335 THR Q CA  1 
ATOM   5476  C  C   . THR D 3 94  ? -20.637 -5.791  5.985  1   122.31 ? 335 THR Q C   1 
ATOM   5477  O  O   . THR D 3 94  ? -20.636 -4.659  6.512  1   125.37 ? 335 THR Q O   1 
ATOM   5478  C  CB  . THR D 3 94  ? -21.935 -5.722  3.793  1   126.32 ? 335 THR Q CB  1 
ATOM   5479  O  OG1 . THR D 3 94  ? -23.153 -6.171  3.196  1   123.97 ? 335 THR Q OG1 1 
ATOM   5480  C  CG2 . THR D 3 94  ? -20.769 -6.187  2.947  1   127.29 ? 335 THR Q CG2 1 
ATOM   5481  N  N   . ALA D 3 95  ? -19.612 -6.652  6.02   1   119.56 ? 336 ALA Q N   1 
ATOM   5482  C  CA  . ALA D 3 95  ? -18.274 -6.388  6.607  1   115.6  ? 336 ALA Q CA  1 
ATOM   5483  C  C   . ALA D 3 95  ? -17.191 -7.087  5.773  1   110.25 ? 336 ALA Q C   1 
ATOM   5484  O  O   . ALA D 3 95  ? -17.337 -8.298  5.509  1   103.05 ? 336 ALA Q O   1 
ATOM   5485  C  CB  . ALA D 3 95  ? -18.241 -6.849  8.043  1   115.02 ? 336 ALA Q CB  1 
ATOM   5486  N  N   . THR D 3 96  ? -16.142 -6.344  5.395  1   106.33 ? 337 THR Q N   1 
ATOM   5487  C  CA  . THR D 3 96  ? -15.019 -6.785  4.522  1   102.67 ? 337 THR Q CA  1 
ATOM   5488  C  C   . THR D 3 96  ? -13.712 -6.734  5.328  1   100.43 ? 337 THR Q C   1 
ATOM   5489  O  O   . THR D 3 96  ? -13.516 -5.74   6.059  1   99.18  ? 337 THR Q O   1 
ATOM   5490  C  CB  . THR D 3 96  ? -14.992 -5.931  3.244  1   100.66 ? 337 THR Q CB  1 
ATOM   5491  O  OG1 . THR D 3 96  ? -16.021 -6.433  2.391  1   97.94  ? 337 THR Q OG1 1 
ATOM   5492  C  CG2 . THR D 3 96  ? -13.675 -5.952  2.499  1   100.28 ? 337 THR Q CG2 1 
ATOM   5493  N  N   . LEU D 3 97  ? -12.861 -7.761  5.195  1   94.98  ? 338 LEU Q N   1 
ATOM   5494  C  CA  . LEU D 3 97  ? -11.516 -7.831  5.834  1   89.03  ? 338 LEU Q CA  1 
ATOM   5495  C  C   . LEU D 3 97  ? -10.581 -8.717  4.998  1   82.44  ? 338 LEU Q C   1 
ATOM   5496  O  O   . LEU D 3 97  ? -10.961 -9.866  4.717  1   75.72  ? 338 LEU Q O   1 
ATOM   5497  C  CB  . LEU D 3 97  ? -11.661 -8.369  7.264  1   88.26  ? 338 LEU Q CB  1 
ATOM   5498  C  CG  . LEU D 3 97  ? -10.374 -8.458  8.089  1   86.25  ? 338 LEU Q CG  1 
ATOM   5499  C  CD1 . LEU D 3 97  ? -9.731  -7.092  8.28   1   84.84  ? 338 LEU Q CD1 1 
ATOM   5500  C  CD2 . LEU D 3 97  ? -10.643 -9.099  9.438  1   85.15  ? 338 LEU Q CD2 1 
ATOM   5501  N  N   . SER D 3 98  ? -9.41   -8.185  4.626  1   80.46  ? 339 SER Q N   1 
ATOM   5502  C  CA  . SER D 3 98  ? -8.285  -8.905  3.969  1   79.75  ? 339 SER Q CA  1 
ATOM   5503  C  C   . SER D 3 98  ? -6.994  -8.696  4.771  1   79.93  ? 339 SER Q C   1 
ATOM   5504  O  O   . SER D 3 98  ? -6.998  -7.858  5.699  1   78.82  ? 339 SER Q O   1 
ATOM   5505  C  CB  . SER D 3 98  ? -8.116  -8.457  2.537  1   77.65  ? 339 SER Q CB  1 
ATOM   5506  O  OG  . SER D 3 98  ? -7.495  -7.182  2.463  1   76.15  ? 339 SER Q OG  1 
ATOM   5507  N  N   . LYS D 3 99  ? -5.934  -9.433  4.422  1   82.46  ? 340 LYS Q N   1 
ATOM   5508  C  CA  . LYS D 3 99  ? -4.557  -9.218  4.949  1   83.28  ? 340 LYS Q CA  1 
ATOM   5509  C  C   . LYS D 3 99  ? -4.102  -7.81   4.54   1   82.7   ? 340 LYS Q C   1 
ATOM   5510  O  O   . LYS D 3 99  ? -4.383  -7.408  3.392  1   79.87  ? 340 LYS Q O   1 
ATOM   5511  C  CB  . LYS D 3 99  ? -3.591  -10.291 4.431  1   85.72  ? 340 LYS Q CB  1 
ATOM   5512  C  CG  . LYS D 3 99  ? -2.266  -10.384 5.178  1   89.87  ? 340 LYS Q CG  1 
ATOM   5513  C  CD  . LYS D 3 99  ? -1.114  -10.935 4.357  1   90.07  ? 340 LYS Q CD  1 
ATOM   5514  C  CE  . LYS D 3 99  ? 0.202   -10.891 5.105  1   90.4   ? 340 LYS Q CE  1 
ATOM   5515  N  NZ  . LYS D 3 99  ? 1.357   -11.125 4.207  1   91.99  ? 340 LYS Q NZ  1 
ATOM   5516  N  N   . SER D 3 100 ? -3.445  -7.088  5.453  1   82.88  ? 341 SER Q N   1 
ATOM   5517  C  CA  . SER D 3 100 ? -3.052  -5.662  5.293  1   83.58  ? 341 SER Q CA  1 
ATOM   5518  C  C   . SER D 3 100 ? -1.966  -5.523  4.218  1   83.92  ? 341 SER Q C   1 
ATOM   5519  O  O   . SER D 3 100 ? -1.138  -6.45   4.081  1   82.41  ? 341 SER Q O   1 
ATOM   5520  C  CB  . SER D 3 100 ? -2.602  -5.069  6.607  1   82.23  ? 341 SER Q CB  1 
ATOM   5521  O  OG  . SER D 3 100 ? -3.597  -5.241  7.605  1   78.71  ? 341 SER Q OG  1 
ATOM   5522  N  N   . GLY D 3 101 ? -1.993  -4.411  3.476  1   85.59  ? 342 GLY Q N   1 
ATOM   5523  C  CA  . GLY D 3 101 ? -0.938  -4.004  2.528  1   87.64  ? 342 GLY Q CA  1 
ATOM   5524  C  C   . GLY D 3 101 ? 0.083   -3.109  3.208  1   88.94  ? 342 GLY Q C   1 
ATOM   5525  O  O   . GLY D 3 101 ? -0.038  -2.909  4.436  1   86.69  ? 342 GLY Q O   1 
ATOM   5526  N  N   . ASN D 3 102 ? 1.049   -2.591  2.438  1   90.9   ? 343 ASN Q N   1 
ATOM   5527  C  CA  . ASN D 3 102 ? 2.126   -1.671  2.9    1   89.14  ? 343 ASN Q CA  1 
ATOM   5528  C  C   . ASN D 3 102 ? 2.759   -2.236  4.181  1   87.31  ? 343 ASN Q C   1 
ATOM   5529  O  O   . ASN D 3 102 ? 2.801   -1.504  5.189  1   87.41  ? 343 ASN Q O   1 
ATOM   5530  C  CB  . ASN D 3 102 ? 1.6     -0.241  3.079  1   86.88  ? 343 ASN Q CB  1 
ATOM   5531  C  CG  . ASN D 3 102 ? 1.044   0.385   1.848  0   88.94  ? 343 ASN Q CG  1 
ATOM   5532  O  OD1 . ASN D 3 102 ? 0.841   -0.297  0.845  0   88.78  ? 343 ASN Q OD1 1 
ATOM   5533  N  ND2 . ASN D 3 102 ? 0.785   1.682   1.889  0   88.81  ? 343 ASN Q ND2 1 
ATOM   5534  N  N   . THR D 3 103 ? 3.225   -3.491  4.133  1   81.16  ? 344 THR Q N   1 
ATOM   5535  C  CA  . THR D 3 103 ? 3.871   -4.21   5.268  1   77.55  ? 344 THR Q CA  1 
ATOM   5536  C  C   . THR D 3 103 ? 5.312   -3.708  5.421  1   76.91  ? 344 THR Q C   1 
ATOM   5537  O  O   . THR D 3 103 ? 5.932   -3.397  4.387  1   78.27  ? 344 THR Q O   1 
ATOM   5538  C  CB  . THR D 3 103 ? 3.867   -5.738  5.092  1   76.73  ? 344 THR Q CB  1 
ATOM   5539  O  OG1 . THR D 3 103 ? 4.806   -6.106  4.079  1   73.95  ? 344 THR Q OG1 1 
ATOM   5540  C  CG2 . THR D 3 103 ? 2.506   -6.311  4.756  1   77.33  ? 344 THR Q CG2 1 
ATOM   5541  N  N   . PHE D 3 104 ? 5.814   -3.634  6.658  1   77.29  ? 345 PHE Q N   1 
ATOM   5542  C  CA  . PHE D 3 104 ? 7.234   -3.338  6.993  1   78.04  ? 345 PHE Q CA  1 
ATOM   5543  C  C   . PHE D 3 104 ? 7.704   -4.314  8.078  1   77.95  ? 345 PHE Q C   1 
ATOM   5544  O  O   . PHE D 3 104 ? 6.918   -4.627  8.999  1   78.84  ? 345 PHE Q O   1 
ATOM   5545  C  CB  . PHE D 3 104 ? 7.414   -1.882  7.435  1   81.33  ? 345 PHE Q CB  1 
ATOM   5546  C  CG  . PHE D 3 104 ? 7.061   -0.853  6.389  1   85.23  ? 345 PHE Q CG  1 
ATOM   5547  C  CD1 . PHE D 3 104 ? 7.688   -0.851  5.15   1   85.58  ? 345 PHE Q CD1 1 
ATOM   5548  C  CD2 . PHE D 3 104 ? 6.107   0.124   6.643  1   86.4   ? 345 PHE Q CD2 1 
ATOM   5549  C  CE1 . PHE D 3 104 ? 7.353   0.09    4.187  1   87.34  ? 345 PHE Q CE1 1 
ATOM   5550  C  CE2 . PHE D 3 104 ? 5.773   1.064   5.68   1   86.62  ? 345 PHE Q CE2 1 
ATOM   5551  C  CZ  . PHE D 3 104 ? 6.398   1.047   4.454  1   87.87  ? 345 PHE Q CZ  1 
ATOM   5552  N  N   . ARG D 3 105 ? 8.951   -4.783  7.961  1   76     ? 346 ARG Q N   1 
ATOM   5553  C  CA  . ARG D 3 105 ? 9.583   -5.734  8.913  1   73.78  ? 346 ARG Q CA  1 
ATOM   5554  C  C   . ARG D 3 105 ? 9.878   -4.996  10.214 1   67.29  ? 346 ARG Q C   1 
ATOM   5555  O  O   . ARG D 3 105 ? 10.301  -3.844  10.168 1   66.74  ? 346 ARG Q O   1 
ATOM   5556  C  CB  . ARG D 3 105 ? 10.899  -6.292  8.362  1   80.35  ? 346 ARG Q CB  1 
ATOM   5557  C  CG  . ARG D 3 105 ? 10.786  -7.002  7.021  1   85.06  ? 346 ARG Q CG  1 
ATOM   5558  C  CD  . ARG D 3 105 ? 12.108  -7.648  6.662  1   89.84  ? 346 ARG Q CD  1 
ATOM   5559  N  NE  . ARG D 3 105 ? 12.131  -8.207  5.316  1   95.23  ? 346 ARG Q NE  1 
ATOM   5560  C  CZ  . ARG D 3 105 ? 13.137  -8.912  4.791  1   96.9   ? 346 ARG Q CZ  1 
ATOM   5561  N  NH1 . ARG D 3 105 ? 14.234  -9.162  5.494  1   95.66  ? 346 ARG Q NH1 1 
ATOM   5562  N  NH2 . ARG D 3 105 ? 13.041  -9.37   3.553  1   97.46  ? 346 ARG Q NH2 1 
ATOM   5563  N  N   . PRO D 3 106 ? 9.68    -5.611  11.403 1   63.53  ? 347 PRO Q N   1 
ATOM   5564  C  CA  . PRO D 3 106 ? 10.132  -5.009  12.654 1   60.82  ? 347 PRO Q CA  1 
ATOM   5565  C  C   . PRO D 3 106 ? 11.664  -4.938  12.711 1   59.31  ? 347 PRO Q C   1 
ATOM   5566  O  O   . PRO D 3 106 ? 12.312  -5.888  12.316 1   58.18  ? 347 PRO Q O   1 
ATOM   5567  C  CB  . PRO D 3 106 ? 9.581   -5.945  13.739 1   60.82  ? 347 PRO Q CB  1 
ATOM   5568  C  CG  . PRO D 3 106 ? 9.433   -7.268  13.037 1   62.2   ? 347 PRO Q CG  1 
ATOM   5569  C  CD  . PRO D 3 106 ? 9.007   -6.898  11.633 1   63.96  ? 347 PRO Q CD  1 
ATOM   5570  N  N   . GLU D 3 107 ? 12.191  -3.793  13.146 1   57.18  ? 348 GLU Q N   1 
ATOM   5571  C  CA  . GLU D 3 107 ? 13.586  -3.646  13.628 1   56.34  ? 348 GLU Q CA  1 
ATOM   5572  C  C   . GLU D 3 107 ? 13.567  -4.036  15.108 1   52.08  ? 348 GLU Q C   1 
ATOM   5573  O  O   . GLU D 3 107 ? 12.818  -3.394  15.872 1   49.72  ? 348 GLU Q O   1 
ATOM   5574  C  CB  . GLU D 3 107 ? 14.106  -2.222  13.402 1   60.66  ? 348 GLU Q CB  1 
ATOM   5575  C  CG  . GLU D 3 107 ? 13.986  -1.732  11.962 1   66.35  ? 348 GLU Q CG  1 
ATOM   5576  C  CD  . GLU D 3 107 ? 14.68   -2.585  10.908 1   71     ? 348 GLU Q CD  1 
ATOM   5577  O  OE1 . GLU D 3 107 ? 15.896  -2.847  11.057 1   71.95  ? 348 GLU Q OE1 1 
ATOM   5578  O  OE2 . GLU D 3 107 ? 14      -2.997  9.941  1   74.9   ? 348 GLU Q OE2 1 
ATOM   5579  N  N   . VAL D 3 108 ? 14.316  -5.077  15.482 1   49.25  ? 349 VAL Q N   1 
ATOM   5580  C  CA  . VAL D 3 108 ? 14.332  -5.639  16.865 1   48.14  ? 349 VAL Q CA  1 
ATOM   5581  C  C   . VAL D 3 108 ? 15.677  -5.302  17.51  1   47.7   ? 349 VAL Q C   1 
ATOM   5582  O  O   . VAL D 3 108 ? 16.717  -5.581  16.894 1   46.44  ? 349 VAL Q O   1 
ATOM   5583  C  CB  . VAL D 3 108 ? 14.059  -7.152  16.874 1   48.2   ? 349 VAL Q CB  1 
ATOM   5584  C  CG1 . VAL D 3 108 ? 14.031  -7.715  18.29  1   48.79  ? 349 VAL Q CG1 1 
ATOM   5585  C  CG2 . VAL D 3 108 ? 12.765  -7.482  16.148 1   48.59  ? 349 VAL Q CG2 1 
ATOM   5586  N  N   . HIS D 3 109 ? 15.627  -4.725  18.713 1   48.13  ? 350 HIS Q N   1 
ATOM   5587  C  CA  . HIS D 3 109 ? 16.798  -4.301  19.52  1   48.67  ? 350 HIS Q CA  1 
ATOM   5588  C  C   . HIS D 3 109 ? 16.626  -4.829  20.945 1   48.54  ? 350 HIS Q C   1 
ATOM   5589  O  O   . HIS D 3 109 ? 15.609  -4.48   21.581 1   52.02  ? 350 HIS Q O   1 
ATOM   5590  C  CB  . HIS D 3 109 ? 16.94   -2.776  19.494 1   49.77  ? 350 HIS Q CB  1 
ATOM   5591  C  CG  . HIS D 3 109 ? 16.808  -2.189  18.129 1   51.71  ? 350 HIS Q CG  1 
ATOM   5592  N  ND1 . HIS D 3 109 ? 17.747  -2.407  17.141 1   51.26  ? 350 HIS Q ND1 1 
ATOM   5593  C  CD2 . HIS D 3 109 ? 15.86   -1.396  17.586 1   52.41  ? 350 HIS Q CD2 1 
ATOM   5594  C  CE1 . HIS D 3 109 ? 17.382  -1.772  16.046 1   52.22  ? 350 HIS Q CE1 1 
ATOM   5595  N  NE2 . HIS D 3 109 ? 16.229  -1.142  16.293 1   52.54  ? 350 HIS Q NE2 1 
ATOM   5596  N  N   . LEU D 3 110 ? 17.557  -5.665  21.402 1   46.8   ? 351 LEU Q N   1 
ATOM   5597  C  CA  . LEU D 3 110 ? 17.634  -6.126  22.809 1   46.58  ? 351 LEU Q CA  1 
ATOM   5598  C  C   . LEU D 3 110 ? 18.748  -5.325  23.487 1   45.55  ? 351 LEU Q C   1 
ATOM   5599  O  O   . LEU D 3 110 ? 19.908  -5.45   23.067 1   44.95  ? 351 LEU Q O   1 
ATOM   5600  C  CB  . LEU D 3 110 ? 17.89   -7.636  22.844 1   47.85  ? 351 LEU Q CB  1 
ATOM   5601  C  CG  . LEU D 3 110 ? 17.899  -8.295  24.226 1   48.49  ? 351 LEU Q CG  1 
ATOM   5602  C  CD1 . LEU D 3 110 ? 16.59   -8.073  24.978 1   47.79  ? 351 LEU Q CD1 1 
ATOM   5603  C  CD2 . LEU D 3 110 ? 18.175  -9.785  24.096 1   48.7   ? 351 LEU Q CD2 1 
ATOM   5604  N  N   . LEU D 3 111 ? 18.38   -4.501  24.468 1   46.22  ? 352 LEU Q N   1 
ATOM   5605  C  CA  . LEU D 3 111 ? 19.277  -3.518  25.12  1   47.19  ? 352 LEU Q CA  1 
ATOM   5606  C  C   . LEU D 3 111 ? 19.726  -4.096  26.457 1   46.85  ? 352 LEU Q C   1 
ATOM   5607  O  O   . LEU D 3 111 ? 18.911  -4.654  27.188 1   42.69  ? 352 LEU Q O   1 
ATOM   5608  C  CB  . LEU D 3 111 ? 18.53   -2.191  25.296 1   47.96  ? 352 LEU Q CB  1 
ATOM   5609  C  CG  . LEU D 3 111 ? 17.806  -1.669  24.054 1   49.03  ? 352 LEU Q CG  1 
ATOM   5610  C  CD1 . LEU D 3 111 ? 17.053  -0.387  24.369 1   48.92  ? 352 LEU Q CD1 1 
ATOM   5611  C  CD2 . LEU D 3 111 ? 18.773  -1.454  22.896 1   49.43  ? 352 LEU Q CD2 1 
ATOM   5612  N  N   . PRO D 3 112 ? 21.03   -3.985  26.809 1   49.29  ? 353 PRO Q N   1 
ATOM   5613  C  CA  . PRO D 3 112 ? 21.546  -4.573  28.045 1   51.72  ? 353 PRO Q CA  1 
ATOM   5614  C  C   . PRO D 3 112 ? 21.066  -3.8    29.268 1   53.09  ? 353 PRO Q C   1 
ATOM   5615  O  O   . PRO D 3 112 ? 20.559  -2.689  29.131 1   54.12  ? 353 PRO Q O   1 
ATOM   5616  C  CB  . PRO D 3 112 ? 23.069  -4.468  27.878 1   52.39  ? 353 PRO Q CB  1 
ATOM   5617  C  CG  . PRO D 3 112 ? 23.259  -3.258  26.983 1   51.45  ? 353 PRO Q CG  1 
ATOM   5618  C  CD  . PRO D 3 112 ? 22.073  -3.28   26.044 1   49.33  ? 353 PRO Q CD  1 
ATOM   5619  N  N   . PRO D 3 113 ? 21.215  -4.351  30.494 1   54.41  ? 354 PRO Q N   1 
ATOM   5620  C  CA  . PRO D 3 113 ? 20.745  -3.667  31.695 1   56.53  ? 354 PRO Q CA  1 
ATOM   5621  C  C   . PRO D 3 113 ? 21.655  -2.484  32.016 1   60.11  ? 354 PRO Q C   1 
ATOM   5622  O  O   . PRO D 3 113 ? 22.862  -2.55   31.777 1   63.93  ? 354 PRO Q O   1 
ATOM   5623  C  CB  . PRO D 3 113 ? 20.781  -4.751  32.782 1   56.8   ? 354 PRO Q CB  1 
ATOM   5624  C  CG  . PRO D 3 113 ? 21.838  -5.732  32.309 1   57.68  ? 354 PRO Q CG  1 
ATOM   5625  C  CD  . PRO D 3 113 ? 21.866  -5.634  30.796 1   56.2   ? 354 PRO Q CD  1 
ATOM   5626  N  N   . PRO D 3 114 ? 21.108  -1.366  32.548 1   59.91  ? 355 PRO Q N   1 
ATOM   5627  C  CA  . PRO D 3 114 ? 21.91   -0.171  32.817 1   59.47  ? 355 PRO Q CA  1 
ATOM   5628  C  C   . PRO D 3 114 ? 22.874  -0.367  34     1   61.47  ? 355 PRO Q C   1 
ATOM   5629  O  O   . PRO D 3 114 ? 22.544  -1.123  34.902 1   61.66  ? 355 PRO Q O   1 
ATOM   5630  C  CB  . PRO D 3 114 ? 20.844  0.894   33.12  1   59.47  ? 355 PRO Q CB  1 
ATOM   5631  C  CG  . PRO D 3 114 ? 19.687  0.108   33.706 1   59.07  ? 355 PRO Q CG  1 
ATOM   5632  C  CD  . PRO D 3 114 ? 19.7    -1.203  32.949 1   59.61  ? 355 PRO Q CD  1 
ATOM   5633  N  N   . SER D 3 115 ? 24.028  0.315   33.96  1   64.78  ? 356 SER Q N   1 
ATOM   5634  C  CA  . SER D 3 115 ? 25.111  0.301   34.986 1   67.43  ? 356 SER Q CA  1 
ATOM   5635  C  C   . SER D 3 115 ? 24.527  0.416   36.402 1   70.27  ? 356 SER Q C   1 
ATOM   5636  O  O   . SER D 3 115 ? 25.03   -0.282  37.304 1   67.65  ? 356 SER Q O   1 
ATOM   5637  C  CB  . SER D 3 115 ? 26.111  1.407   34.738 1   69.24  ? 356 SER Q CB  1 
ATOM   5638  O  OG  . SER D 3 115 ? 26.458  1.489   33.364 1   73.47  ? 356 SER Q OG  1 
ATOM   5639  N  N   . GLU D 3 116 ? 23.514  1.277   36.571 1   73.4   ? 357 GLU Q N   1 
ATOM   5640  C  CA  . GLU D 3 116 ? 22.808  1.567   37.852 1   75.55  ? 357 GLU Q CA  1 
ATOM   5641  C  C   . GLU D 3 116 ? 22.34   0.256   38.502 1   69.94  ? 357 GLU Q C   1 
ATOM   5642  O  O   . GLU D 3 116 ? 22.69   0.022   39.675 1   65.85  ? 357 GLU Q O   1 
ATOM   5643  C  CB  . GLU D 3 116 ? 21.609  2.489   37.598 1   82.03  ? 357 GLU Q CB  1 
ATOM   5644  C  CG  . GLU D 3 116 ? 21.983  3.871   37.068 1   88.57  ? 357 GLU Q CG  1 
ATOM   5645  C  CD  . GLU D 3 116 ? 21.138  4.429   35.928 1   95.02  ? 357 GLU Q CD  1 
ATOM   5646  O  OE1 . GLU D 3 116 ? 20.445  3.649   35.241 1   90.29  ? 357 GLU Q OE1 1 
ATOM   5647  O  OE2 . GLU D 3 116 ? 21.178  5.663   35.722 1   103.88 ? 357 GLU Q OE2 1 
ATOM   5648  N  N   . GLU D 3 117 ? 21.583  -0.559  37.76  1   67.46  ? 358 GLU Q N   1 
ATOM   5649  C  CA  . GLU D 3 117 ? 20.969  -1.825  38.254 1   66.34  ? 358 GLU Q CA  1 
ATOM   5650  C  C   . GLU D 3 117 ? 22.061  -2.857  38.549 1   65.09  ? 358 GLU Q C   1 
ATOM   5651  O  O   . GLU D 3 117 ? 21.976  -3.502  39.614 1   67.19  ? 358 GLU Q O   1 
ATOM   5652  C  CB  . GLU D 3 117 ? 19.97   -2.403  37.247 1   65.02  ? 358 GLU Q CB  1 
ATOM   5653  C  CG  . GLU D 3 117 ? 18.558  -1.881  37.422 1   62.56  ? 358 GLU Q CG  1 
ATOM   5654  C  CD  . GLU D 3 117 ? 17.531  -2.569  36.542 1   61.51  ? 358 GLU Q CD  1 
ATOM   5655  O  OE1 . GLU D 3 117 ? 17.901  -2.997  35.428 1   61.08  ? 358 GLU Q OE1 1 
ATOM   5656  O  OE2 . GLU D 3 117 ? 16.366  -2.68   36.976 1   58.96  ? 358 GLU Q OE2 1 
ATOM   5657  N  N   . LEU D 3 118 ? 23.024  -3.01   37.632 1   65.45  ? 359 LEU Q N   1 
ATOM   5658  C  CA  . LEU D 3 118 ? 24.167  -3.962  37.74  1   67.17  ? 359 LEU Q CA  1 
ATOM   5659  C  C   . LEU D 3 118 ? 24.89   -3.764  39.078 1   67.15  ? 359 LEU Q C   1 
ATOM   5660  O  O   . LEU D 3 118 ? 25.13   -4.776  39.766 1   70.87  ? 359 LEU Q O   1 
ATOM   5661  C  CB  . LEU D 3 118 ? 25.122  -3.749  36.56  1   68.28  ? 359 LEU Q CB  1 
ATOM   5662  C  CG  . LEU D 3 118 ? 24.63   -4.282  35.216 1   68.45  ? 359 LEU Q CG  1 
ATOM   5663  C  CD1 . LEU D 3 118 ? 25.351  -3.606  34.057 1   69.49  ? 359 LEU Q CD1 1 
ATOM   5664  C  CD2 . LEU D 3 118 ? 24.796  -5.793  35.144 1   67.97  ? 359 LEU Q CD2 1 
ATOM   5665  N  N   . ALA D 3 119 ? 25.2    -2.51   39.427 1   66.67  ? 360 ALA Q N   1 
ATOM   5666  C  CA  . ALA D 3 119 ? 25.909  -2.103  40.666 1   66.69  ? 360 ALA Q CA  1 
ATOM   5667  C  C   . ALA D 3 119 ? 25.111  -2.518  41.911 1   67.11  ? 360 ALA Q C   1 
ATOM   5668  O  O   . ALA D 3 119 ? 25.741  -3.02   42.863 1   66.71  ? 360 ALA Q O   1 
ATOM   5669  C  CB  . ALA D 3 119 ? 26.164  -0.614  40.65  1   66.21  ? 360 ALA Q CB  1 
ATOM   5670  N  N   . LEU D 3 120 ? 23.787  -2.313  41.908 1   67.62  ? 361 LEU Q N   1 
ATOM   5671  C  CA  . LEU D 3 120 ? 22.882  -2.654  43.044 1   69.81  ? 361 LEU Q CA  1 
ATOM   5672  C  C   . LEU D 3 120 ? 22.812  -4.178  43.227 1   71.7   ? 361 LEU Q C   1 
ATOM   5673  O  O   . LEU D 3 120 ? 22.518  -4.613  44.357 1   69.08  ? 361 LEU Q O   1 
ATOM   5674  C  CB  . LEU D 3 120 ? 21.492  -2.055  42.804 1   72.06  ? 361 LEU Q CB  1 
ATOM   5675  C  CG  . LEU D 3 120 ? 21.399  -0.532  42.915 1   74.42  ? 361 LEU Q CG  1 
ATOM   5676  C  CD1 . LEU D 3 120 ? 20.118  -0.017  42.274 1   74.99  ? 361 LEU Q CD1 1 
ATOM   5677  C  CD2 . LEU D 3 120 ? 21.485  -0.078  44.367 1   74.83  ? 361 LEU Q CD2 1 
ATOM   5678  N  N   . ASN D 3 121 ? 23.04   -4.943  42.151 1   75.17  ? 362 ASN Q N   1 
ATOM   5679  C  CA  . ASN D 3 121 ? 23.325  -6.408  42.155 1   76.53  ? 362 ASN Q CA  1 
ATOM   5680  C  C   . ASN D 3 121 ? 22.18   -7.198  42.819 1   74.43  ? 362 ASN Q C   1 
ATOM   5681  O  O   . ASN D 3 121 ? 22.477  -8.197  43.512 1   73.34  ? 362 ASN Q O   1 
ATOM   5682  C  CB  . ASN D 3 121 ? 24.697  -6.691  42.783 1   77.73  ? 362 ASN Q CB  1 
ATOM   5683  C  CG  . ASN D 3 121 ? 25.379  -7.908  42.193 1   78.99  ? 362 ASN Q CG  1 
ATOM   5684  O  OD1 . ASN D 3 121 ? 26.338  -7.779  41.435 1   81.01  ? 362 ASN Q OD1 1 
ATOM   5685  N  ND2 . ASN D 3 121 ? 24.882  -9.092  42.514 1   79.85  ? 362 ASN Q ND2 1 
ATOM   5686  N  N   . GLU D 3 122 ? 20.925  -6.779  42.6   1   74.19  ? 363 GLU Q N   1 
ATOM   5687  C  CA  . GLU D 3 122 ? 19.691  -7.543  42.938 1   72.22  ? 363 GLU Q CA  1 
ATOM   5688  C  C   . GLU D 3 122 ? 19.111  -8.059  41.614 1   69.35  ? 363 GLU Q C   1 
ATOM   5689  O  O   . GLU D 3 122 ? 19.757  -8.94   41.016 1   70.24  ? 363 GLU Q O   1 
ATOM   5690  C  CB  . GLU D 3 122 ? 18.733  -6.675  43.76  1   75.28  ? 363 GLU Q CB  1 
ATOM   5691  C  CG  . GLU D 3 122 ? 19.161  -6.498  45.206 1   81.62  ? 363 GLU Q CG  1 
ATOM   5692  C  CD  . GLU D 3 122 ? 18.889  -7.685  46.119 1   87.59  ? 363 GLU Q CD  1 
ATOM   5693  O  OE1 . GLU D 3 122 ? 19.676  -7.891  47.07  1   91.42  ? 363 GLU Q OE1 1 
ATOM   5694  O  OE2 . GLU D 3 122 ? 17.887  -8.397  45.89  1   88.71  ? 363 GLU Q OE2 1 
ATOM   5695  N  N   . LEU D 3 123 ? 17.975  -7.524  41.151 1   65.03  ? 364 LEU Q N   1 
ATOM   5696  C  CA  . LEU D 3 123 ? 17.411  -7.813  39.806 1   60.44  ? 364 LEU Q CA  1 
ATOM   5697  C  C   . LEU D 3 123 ? 17.887  -6.729  38.83  1   58.4   ? 364 LEU Q C   1 
ATOM   5698  O  O   . LEU D 3 123 ? 18.022  -5.562  39.249 1   60.58  ? 364 LEU Q O   1 
ATOM   5699  C  CB  . LEU D 3 123 ? 15.882  -7.878  39.896 1   60.69  ? 364 LEU Q CB  1 
ATOM   5700  C  CG  . LEU D 3 123 ? 15.319  -9.036  40.724 1   60.59  ? 364 LEU Q CG  1 
ATOM   5701  C  CD1 . LEU D 3 123 ? 13.842  -8.831  41.02  1   59.1   ? 364 LEU Q CD1 1 
ATOM   5702  C  CD2 . LEU D 3 123 ? 15.532  -10.369 40.019 1   61.72  ? 364 LEU Q CD2 1 
ATOM   5703  N  N   . VAL D 3 124 ? 18.185  -7.126  37.592 1   54.06  ? 365 VAL Q N   1 
ATOM   5704  C  CA  . VAL D 3 124 ? 18.544  -6.226  36.459 1   52.51  ? 365 VAL Q CA  1 
ATOM   5705  C  C   . VAL D 3 124 ? 17.482  -6.421  35.374 1   52.66  ? 365 VAL Q C   1 
ATOM   5706  O  O   . VAL D 3 124 ? 16.884  -7.514  35.323 1   56.41  ? 365 VAL Q O   1 
ATOM   5707  C  CB  . VAL D 3 124 ? 19.969  -6.495  35.934 1   54.51  ? 365 VAL Q CB  1 
ATOM   5708  C  CG1 . VAL D 3 124 ? 20.994  -6.483  37.061 1   55.3   ? 365 VAL Q CG1 1 
ATOM   5709  C  CG2 . VAL D 3 124 ? 20.079  -7.791  35.136 1   54.85  ? 365 VAL Q CG2 1 
ATOM   5710  N  N   . THR D 3 125 ? 17.282  -5.41   34.529 1   51.33  ? 366 THR Q N   1 
ATOM   5711  C  CA  . THR D 3 125 ? 16.165  -5.325  33.556 1   48.89  ? 366 THR Q CA  1 
ATOM   5712  C  C   . THR D 3 125 ? 16.724  -5.392  32.132 1   49.01  ? 366 THR Q C   1 
ATOM   5713  O  O   . THR D 3 125 ? 17.601  -4.573  31.806 1   50.24  ? 366 THR Q O   1 
ATOM   5714  C  CB  . THR D 3 125 ? 15.342  -4.055  33.798 1   47.98  ? 366 THR Q CB  1 
ATOM   5715  O  OG1 . THR D 3 125 ? 14.995  -3.99   35.182 1   49.2   ? 366 THR Q OG1 1 
ATOM   5716  C  CG2 . THR D 3 125 ? 14.072  -4.028  32.983 1   47.04  ? 366 THR Q CG2 1 
ATOM   5717  N  N   . LEU D 3 126 ? 16.229  -6.336  31.327 1   46.82  ? 367 LEU Q N   1 
ATOM   5718  C  CA  . LEU D 3 126 ? 16.489  -6.428  29.865 1   44.72  ? 367 LEU Q CA  1 
ATOM   5719  C  C   . LEU D 3 126 ? 15.278  -5.846  29.132 1   42.91  ? 367 LEU Q C   1 
ATOM   5720  O  O   . LEU D 3 126 ? 14.145  -6.2    29.489 1   43.58  ? 367 LEU Q O   1 
ATOM   5721  C  CB  . LEU D 3 126 ? 16.717  -7.89   29.474 1   45.91  ? 367 LEU Q CB  1 
ATOM   5722  C  CG  . LEU D 3 126 ? 17.892  -8.574  30.168 1   46.84  ? 367 LEU Q CG  1 
ATOM   5723  C  CD1 . LEU D 3 126 ? 17.733  -10.079 30.137 1   49.32  ? 367 LEU Q CD1 1 
ATOM   5724  C  CD2 . LEU D 3 126 ? 19.205  -8.167  29.53  1   48.47  ? 367 LEU Q CD2 1 
ATOM   5725  N  N   . THR D 3 127 ? 15.524  -4.988  28.146 1   41.97  ? 368 THR Q N   1 
ATOM   5726  C  CA  . THR D 3 127 ? 14.5    -4.209  27.411 1   40.94  ? 368 THR Q CA  1 
ATOM   5727  C  C   . THR D 3 127 ? 14.537  -4.661  25.95  1   41.96  ? 368 THR Q C   1 
ATOM   5728  O  O   . THR D 3 127 ? 15.579  -4.45   25.296 1   41.54  ? 368 THR Q O   1 
ATOM   5729  C  CB  . THR D 3 127 ? 14.75   -2.705  27.594 1   40.66  ? 368 THR Q CB  1 
ATOM   5730  O  OG1 . THR D 3 127 ? 14.933  -2.463  28.991 1   40.93  ? 368 THR Q OG1 1 
ATOM   5731  C  CG2 . THR D 3 127 ? 13.632  -1.841  27.055 1   39.73  ? 368 THR Q CG2 1 
ATOM   5732  N  N   . CYS D 3 128 ? 13.464  -5.302  25.48  1   43.35  ? 369 CYS Q N   1 
ATOM   5733  C  CA  . CYS D 3 128 ? 13.266  -5.666  24.054 1   44.27  ? 369 CYS Q CA  1 
ATOM   5734  C  C   . CYS D 3 128 ? 12.427  -4.565  23.401 1   43.16  ? 369 CYS Q C   1 
ATOM   5735  O  O   . CYS D 3 128 ? 11.343  -4.268  23.915 1   42.28  ? 369 CYS Q O   1 
ATOM   5736  C  CB  . CYS D 3 128 ? 12.623  -7.04   23.901 1   45.59  ? 369 CYS Q CB  1 
ATOM   5737  S  SG  . CYS D 3 128 ? 12.404  -7.537  22.172 1   47.94  ? 369 CYS Q SG  1 
ATOM   5738  N  N   . LEU D 3 129 ? 12.951  -3.96   22.334 1   43.42  ? 370 LEU Q N   1 
ATOM   5739  C  CA  . LEU D 3 129 ? 12.264  -2.932  21.513 1   42.89  ? 370 LEU Q CA  1 
ATOM   5740  C  C   . LEU D 3 129 ? 12.09   -3.487  20.1   1   42.48  ? 370 LEU Q C   1 
ATOM   5741  O  O   . LEU D 3 129 ? 13.117  -3.702  19.429 1   42.33  ? 370 LEU Q O   1 
ATOM   5742  C  CB  . LEU D 3 129 ? 13.112  -1.655  21.505 1   42.61  ? 370 LEU Q CB  1 
ATOM   5743  C  CG  . LEU D 3 129 ? 12.696  -0.575  20.508 1   42.04  ? 370 LEU Q CG  1 
ATOM   5744  C  CD1 . LEU D 3 129 ? 11.297  -0.057  20.802 1   42.38  ? 370 LEU Q CD1 1 
ATOM   5745  C  CD2 . LEU D 3 129 ? 13.7    0.559   20.517 1   43.12  ? 370 LEU Q CD2 1 
ATOM   5746  N  N   . ALA D 3 130 ? 10.843  -3.719  19.687 1   42.73  ? 371 ALA Q N   1 
ATOM   5747  C  CA  . ALA D 3 130 ? 10.459  -3.998  18.284 1   45.09  ? 371 ALA Q CA  1 
ATOM   5748  C  C   . ALA D 3 130 ? 9.83    -2.722  17.722 1   46.06  ? 371 ALA Q C   1 
ATOM   5749  O  O   . ALA D 3 130 ? 8.924   -2.18   18.374 1   45.64  ? 371 ALA Q O   1 
ATOM   5750  C  CB  . ALA D 3 130 ? 9.524   -5.183  18.209 1   44.29  ? 371 ALA Q CB  1 
ATOM   5751  N  N   . ARG D 3 131 ? 10.302  -2.273  16.559 1   48.31  ? 372 ARG Q N   1 
ATOM   5752  C  CA  . ARG D 3 131 ? 10.094  -0.897  16.038 1   49.4   ? 372 ARG Q CA  1 
ATOM   5753  C  C   . ARG D 3 131 ? 10.008  -0.93   14.508 1   49.41  ? 372 ARG Q C   1 
ATOM   5754  O  O   . ARG D 3 131 ? 10.753  -1.721  13.901 1   50.94  ? 372 ARG Q O   1 
ATOM   5755  C  CB  . ARG D 3 131 ? 11.263  -0.019  16.498 1   51.8   ? 372 ARG Q CB  1 
ATOM   5756  C  CG  . ARG D 3 131 ? 10.998  1.475   16.397 1   54.56  ? 372 ARG Q CG  1 
ATOM   5757  C  CD  . ARG D 3 131 ? 12.201  2.31    15.993 1   52.87  ? 372 ARG Q CD  1 
ATOM   5758  N  NE  . ARG D 3 131 ? 12.646  1.997   14.643 1   53.29  ? 372 ARG Q NE  1 
ATOM   5759  C  CZ  . ARG D 3 131 ? 12.017  2.336   13.513 1   53.65  ? 372 ARG Q CZ  1 
ATOM   5760  N  NH1 . ARG D 3 131 ? 10.883  3.021   13.531 1   49.23  ? 372 ARG Q NH1 1 
ATOM   5761  N  NH2 . ARG D 3 131 ? 12.536  1.974   12.35  1   57.55  ? 372 ARG Q NH2 1 
ATOM   5762  N  N   . GLY D 3 132 ? 9.13    -0.11   13.921 1   47.64  ? 373 GLY Q N   1 
ATOM   5763  C  CA  . GLY D 3 132 ? 9.141   0.238   12.487 1   47.85  ? 373 GLY Q CA  1 
ATOM   5764  C  C   . GLY D 3 132 ? 8.348   -0.722  11.612 1   48.63  ? 373 GLY Q C   1 
ATOM   5765  O  O   . GLY D 3 132 ? 8.659   -0.768  10.403 1   48.98  ? 373 GLY Q O   1 
ATOM   5766  N  N   . PHE D 3 133 ? 7.34    -1.409  12.174 1   49.56  ? 374 PHE Q N   1 
ATOM   5767  C  CA  . PHE D 3 133 ? 6.526   -2.477  11.522 1   51.24  ? 374 PHE Q CA  1 
ATOM   5768  C  C   . PHE D 3 133 ? 5.096   -1.963  11.283 1   55.42  ? 374 PHE Q C   1 
ATOM   5769  O  O   . PHE D 3 133 ? 4.559   -1.275  12.176 1   57.9   ? 374 PHE Q O   1 
ATOM   5770  C  CB  . PHE D 3 133 ? 6.566   -3.769  12.351 1   51.14  ? 374 PHE Q CB  1 
ATOM   5771  C  CG  . PHE D 3 133 ? 6.11    -3.679  13.792 1   47.93  ? 374 PHE Q CG  1 
ATOM   5772  C  CD1 . PHE D 3 133 ? 4.763   -3.741  14.118 1   45.38  ? 374 PHE Q CD1 1 
ATOM   5773  C  CD2 . PHE D 3 133 ? 7.026   -3.577  14.831 1   47.24  ? 374 PHE Q CD2 1 
ATOM   5774  C  CE1 . PHE D 3 133 ? 4.341   -3.668  15.437 1   43.67  ? 374 PHE Q CE1 1 
ATOM   5775  C  CE2 . PHE D 3 133 ? 6.603   -3.511  16.151 1   46.05  ? 374 PHE Q CE2 1 
ATOM   5776  C  CZ  . PHE D 3 133 ? 5.261   -3.556  16.452 1   44.77  ? 374 PHE Q CZ  1 
ATOM   5777  N  N   . SER D 3 134 ? 4.497   -2.272  10.123 1   59.91  ? 375 SER Q N   1 
ATOM   5778  C  CA  . SER D 3 134 ? 3.302   -1.554  9.586  1   64.87  ? 375 SER Q CA  1 
ATOM   5779  C  C   . SER D 3 134 ? 1.988   -2.142  10.091 1   65.78  ? 375 SER Q C   1 
ATOM   5780  O  O   . SER D 3 134 ? 1.084   -1.376  10.416 1   68.48  ? 375 SER Q O   1 
ATOM   5781  C  CB  . SER D 3 134 ? 3.296   -1.462  8.085  1   68.75  ? 375 SER Q CB  1 
ATOM   5782  O  OG  . SER D 3 134 ? 2.043   -0.98   7.614  1   74.05  ? 375 SER Q OG  1 
ATOM   5783  N  N   . PRO D 3 135 ? 1.776   -3.48   10.088 1   61.76  ? 376 PRO Q N   1 
ATOM   5784  C  CA  . PRO D 3 135 ? 0.639   -4.064  10.802 1   59.61  ? 376 PRO Q CA  1 
ATOM   5785  C  C   . PRO D 3 135 ? 0.931   -4.053  12.313 1   57.2   ? 376 PRO Q C   1 
ATOM   5786  O  O   . PRO D 3 135 ? 1.995   -4.461  12.705 1   56.46  ? 376 PRO Q O   1 
ATOM   5787  C  CB  . PRO D 3 135 ? 0.495   -5.48   10.215 1   59.74  ? 376 PRO Q CB  1 
ATOM   5788  C  CG  . PRO D 3 135 ? 1.459   -5.513  9.036  1   61.3   ? 376 PRO Q CG  1 
ATOM   5789  C  CD  . PRO D 3 135 ? 2.533   -4.49   9.339  1   59.85  ? 376 PRO Q CD  1 
ATOM   5790  N  N   . LYS D 3 136 ? -0.017  -3.567  13.114 1   58.27  ? 377 LYS Q N   1 
ATOM   5791  C  CA  . LYS D 3 136 ? 0.108   -3.396  14.591 1   61.5   ? 377 LYS Q CA  1 
ATOM   5792  C  C   . LYS D 3 136 ? 0.414   -4.749  15.26  1   59.52  ? 377 LYS Q C   1 
ATOM   5793  O  O   . LYS D 3 136 ? 1.136   -4.745  16.277 1   59     ? 377 LYS Q O   1 
ATOM   5794  C  CB  . LYS D 3 136 ? -1.153  -2.701  15.134 1   66.45  ? 377 LYS Q CB  1 
ATOM   5795  C  CG  . LYS D 3 136 ? -1.657  -3.138  16.505 1   71.61  ? 377 LYS Q CG  1 
ATOM   5796  C  CD  . LYS D 3 136 ? -2.868  -2.361  16.979 1   74.08  ? 377 LYS Q CD  1 
ATOM   5797  C  CE  . LYS D 3 136 ? -3.415  -2.877  18.295 1   78.8   ? 377 LYS Q CE  1 
ATOM   5798  N  NZ  . LYS D 3 136 ? -4.591  -2.155  18.748 0   76.82  ? 377 LYS Q NZ  1 
ATOM   5799  N  N   . ASP D 3 137 ? -0.097  -5.858  14.713 1   57.02  ? 378 ASP Q N   1 
ATOM   5800  C  CA  . ASP D 3 137 ? -0.081  -7.196  15.367 1   56.1   ? 378 ASP Q CA  1 
ATOM   5801  C  C   . ASP D 3 137 ? 1.356   -7.725  15.445 1   53.37  ? 378 ASP Q C   1 
ATOM   5802  O  O   . ASP D 3 137 ? 2.004   -7.848  14.38  1   51.63  ? 378 ASP Q O   1 
ATOM   5803  C  CB  . ASP D 3 137 ? -1.006  -8.171  14.637 1   58.83  ? 378 ASP Q CB  1 
ATOM   5804  C  CG  . ASP D 3 137 ? -2.438  -7.674  14.567 1   61.15  ? 378 ASP Q CG  1 
ATOM   5805  O  OD1 . ASP D 3 137 ? -3.254  -8.123  15.392 1   63.31  ? 378 ASP Q OD1 1 
ATOM   5806  O  OD2 . ASP D 3 137 ? -2.719  -6.83   13.693 1   64.31  ? 378 ASP Q OD2 1 
ATOM   5807  N  N   . VAL D 3 138 ? 1.826   -8.018  16.665 1   50.76  ? 379 VAL Q N   1 
ATOM   5808  C  CA  . VAL D 3 138 ? 3.176   -8.595  16.948 1   49.62  ? 379 VAL Q CA  1 
ATOM   5809  C  C   . VAL D 3 138 ? 3.097   -9.536  18.15  1   47.44  ? 379 VAL Q C   1 
ATOM   5810  O  O   . VAL D 3 138 ? 2.348   -9.231  19.107 1   44.65  ? 379 VAL Q O   1 
ATOM   5811  C  CB  . VAL D 3 138 ? 4.252   -7.523  17.206 1   49.48  ? 379 VAL Q CB  1 
ATOM   5812  C  CG1 . VAL D 3 138 ? 4.703   -6.877  15.912 1   52.21  ? 379 VAL Q CG1 1 
ATOM   5813  C  CG2 . VAL D 3 138 ? 3.804   -6.478  18.216 1   49.2   ? 379 VAL Q CG2 1 
ATOM   5814  N  N   . LEU D 3 139 ? 3.879   -10.615 18.089 1   45.21  ? 380 LEU Q N   1 
ATOM   5815  C  CA  . LEU D 3 139 ? 4.187   -11.509 19.23  1   44.93  ? 380 LEU Q CA  1 
ATOM   5816  C  C   . LEU D 3 139 ? 5.558   -11.123 19.774 1   42.69  ? 380 LEU Q C   1 
ATOM   5817  O  O   . LEU D 3 139 ? 6.45    -10.839 18.952 1   41.04  ? 380 LEU Q O   1 
ATOM   5818  C  CB  . LEU D 3 139 ? 4.189   -12.965 18.756 1   45.23  ? 380 LEU Q CB  1 
ATOM   5819  C  CG  . LEU D 3 139 ? 2.913   -13.441 18.068 1   45.5   ? 380 LEU Q CG  1 
ATOM   5820  C  CD1 . LEU D 3 139 ? 3.044   -14.9   17.667 1   47.34  ? 380 LEU Q CD1 1 
ATOM   5821  C  CD2 . LEU D 3 139 ? 1.693   -13.241 18.955 1   43.89  ? 380 LEU Q CD2 1 
ATOM   5822  N  N   . VAL D 3 140 ? 5.703   -11.127 21.101 1   42.46  ? 381 VAL Q N   1 
ATOM   5823  C  CA  . VAL D 3 140 ? 7.011   -11.003 21.806 1   41.85  ? 381 VAL Q CA  1 
ATOM   5824  C  C   . VAL D 3 140 ? 7.122   -12.148 22.817 1   42.27  ? 381 VAL Q C   1 
ATOM   5825  O  O   . VAL D 3 140 ? 6.222   -12.28  23.671 1   43.7   ? 381 VAL Q O   1 
ATOM   5826  C  CB  . VAL D 3 140 ? 7.171   -9.634  22.49  1   40.37  ? 381 VAL Q CB  1 
ATOM   5827  C  CG1 . VAL D 3 140 ? 8.555   -9.488  23.1   1   40.54  ? 381 VAL Q CG1 1 
ATOM   5828  C  CG2 . VAL D 3 140 ? 6.891   -8.491  21.53  1   41     ? 381 VAL Q CG2 1 
ATOM   5829  N  N   . ARG D 3 141 ? 8.198   -12.927 22.719 1   44.8   ? 382 ARG Q N   1 
ATOM   5830  C  CA  . ARG D 3 141 ? 8.53    -14.048 23.636 1   46.62  ? 382 ARG Q CA  1 
ATOM   5831  C  C   . ARG D 3 141 ? 10      -13.932 24.042 1   44.94  ? 382 ARG Q C   1 
ATOM   5832  O  O   . ARG D 3 141 ? 10.744  -13.193 23.359 1   43.71  ? 382 ARG Q O   1 
ATOM   5833  C  CB  . ARG D 3 141 ? 8.193   -15.374 22.952 1   50.99  ? 382 ARG Q CB  1 
ATOM   5834  C  CG  . ARG D 3 141 ? 6.699   -15.656 22.916 1   54.33  ? 382 ARG Q CG  1 
ATOM   5835  C  CD  . ARG D 3 141 ? 6.284   -16.545 21.768 1   59.88  ? 382 ARG Q CD  1 
ATOM   5836  N  NE  . ARG D 3 141 ? 4.85    -16.804 21.792 1   65.32  ? 382 ARG Q NE  1 
ATOM   5837  C  CZ  . ARG D 3 141 ? 4.205   -17.625 20.96  1   70.6   ? 382 ARG Q CZ  1 
ATOM   5838  N  NH1 . ARG D 3 141 ? 4.858   -18.287 20.014 1   72.66  ? 382 ARG Q NH1 1 
ATOM   5839  N  NH2 . ARG D 3 141 ? 2.896   -17.781 21.082 1   70.57  ? 382 ARG Q NH2 1 
ATOM   5840  N  N   . TRP D 3 142 ? 10.384  -14.603 25.131 1   44.33  ? 383 TRP Q N   1 
ATOM   5841  C  CA  . TRP D 3 142 ? 11.732  -14.5   25.75  1   44.4   ? 383 TRP Q CA  1 
ATOM   5842  C  C   . TRP D 3 142 ? 12.356  -15.887 25.927 1   43.54  ? 383 TRP Q C   1 
ATOM   5843  O  O   . TRP D 3 142 ? 11.614  -16.834 26.241 1   41.27  ? 383 TRP Q O   1 
ATOM   5844  C  CB  . TRP D 3 142 ? 11.645  -13.763 27.09  1   45.79  ? 383 TRP Q CB  1 
ATOM   5845  C  CG  . TRP D 3 142 ? 11.439  -12.284 26.972 1   46.08  ? 383 TRP Q CG  1 
ATOM   5846  C  CD1 . TRP D 3 142 ? 10.25   -11.63  26.856 1   45.12  ? 383 TRP Q CD1 1 
ATOM   5847  C  CD2 . TRP D 3 142 ? 12.455  -11.265 26.977 1   45.21  ? 383 TRP Q CD2 1 
ATOM   5848  N  NE1 . TRP D 3 142 ? 10.454  -10.28  26.787 1   45.07  ? 383 TRP Q NE1 1 
ATOM   5849  C  CE2 . TRP D 3 142 ? 11.794  -10.023 26.863 1   44.21  ? 383 TRP Q CE2 1 
ATOM   5850  C  CE3 . TRP D 3 142 ? 13.851  -11.277 27.064 1   45.77  ? 383 TRP Q CE3 1 
ATOM   5851  C  CZ2 . TRP D 3 142 ? 12.483  -8.811  26.841 1   45.71  ? 383 TRP Q CZ2 1 
ATOM   5852  C  CZ3 . TRP D 3 142 ? 14.532  -10.078 27.05  1   46.67  ? 383 TRP Q CZ3 1 
ATOM   5853  C  CH2 . TRP D 3 142 ? 13.855  -8.861  26.935 1   45.73  ? 383 TRP Q CH2 1 
ATOM   5854  N  N   . LEU D 3 143 ? 13.676  -15.975 25.736 1   44.67  ? 384 LEU Q N   1 
ATOM   5855  C  CA  . LEU D 3 143 ? 14.53   -17.119 26.153 1   45.06  ? 384 LEU Q CA  1 
ATOM   5856  C  C   . LEU D 3 143 ? 15.493  -16.656 27.249 1   45.73  ? 384 LEU Q C   1 
ATOM   5857  O  O   . LEU D 3 143 ? 16.035  -15.55  27.119 1   49.04  ? 384 LEU Q O   1 
ATOM   5858  C  CB  . LEU D 3 143 ? 15.337  -17.639 24.96  1   45.07  ? 384 LEU Q CB  1 
ATOM   5859  C  CG  . LEU D 3 143 ? 14.552  -18.004 23.701 1   46.49  ? 384 LEU Q CG  1 
ATOM   5860  C  CD1 . LEU D 3 143 ? 15.51   -18.387 22.582 1   47.36  ? 384 LEU Q CD1 1 
ATOM   5861  C  CD2 . LEU D 3 143 ? 13.566  -19.134 23.964 1   45.41  ? 384 LEU Q CD2 1 
ATOM   5862  N  N   . GLN D 3 144 ? 15.685  -17.476 28.284 1   47.04  ? 385 GLN Q N   1 
ATOM   5863  C  CA  . GLN D 3 144 ? 16.931  -17.535 29.096 1   47.47  ? 385 GLN Q CA  1 
ATOM   5864  C  C   . GLN D 3 144 ? 17.631  -18.852 28.743 1   46.5   ? 385 GLN Q C   1 
ATOM   5865  O  O   . GLN D 3 144 ? 16.999  -19.91  28.902 1   47.54  ? 385 GLN Q O   1 
ATOM   5866  C  CB  . GLN D 3 144 ? 16.639  -17.442 30.593 1   48.83  ? 385 GLN Q CB  1 
ATOM   5867  C  CG  . GLN D 3 144 ? 17.896  -17.468 31.456 1   48.99  ? 385 GLN Q CG  1 
ATOM   5868  C  CD  . GLN D 3 144 ? 17.605  -17.298 32.927 1   49.67  ? 385 GLN Q CD  1 
ATOM   5869  O  OE1 . GLN D 3 144 ? 16.454  -17.243 33.358 1   51.81  ? 385 GLN Q OE1 1 
ATOM   5870  N  NE2 . GLN D 3 144 ? 18.661  -17.228 33.721 1   50.7   ? 385 GLN Q NE2 1 
ATOM   5871  N  N   . GLY D 3 145 ? 18.878  -18.785 28.273 1   47.21  ? 386 GLY Q N   1 
ATOM   5872  C  CA  . GLY D 3 145 ? 19.569  -19.92  27.634 1   46.9   ? 386 GLY Q CA  1 
ATOM   5873  C  C   . GLY D 3 145 ? 18.786  -20.394 26.424 1   45.73  ? 386 GLY Q C   1 
ATOM   5874  O  O   . GLY D 3 145 ? 18.416  -19.541 25.599 1   44.91  ? 386 GLY Q O   1 
ATOM   5875  N  N   . SER D 3 146 ? 18.501  -21.697 26.349 1   45.58  ? 387 SER Q N   1 
ATOM   5876  C  CA  . SER D 3 146 ? 17.614  -22.325 25.333 1   43.82  ? 387 SER Q CA  1 
ATOM   5877  C  C   . SER D 3 146 ? 16.203  -22.539 25.902 1   42.88  ? 387 SER Q C   1 
ATOM   5878  O  O   . SER D 3 146 ? 15.376  -23.089 25.163 1   44.21  ? 387 SER Q O   1 
ATOM   5879  C  CB  . SER D 3 146 ? 18.217  -23.615 24.815 1   43.47  ? 387 SER Q CB  1 
ATOM   5880  O  OG  . SER D 3 146 ? 18.58   -24.48  25.881 1   41.91  ? 387 SER Q OG  1 
ATOM   5881  N  N   . GLN D 3 147 ? 15.931  -22.115 27.148 1   43.71  ? 388 GLN Q N   1 
ATOM   5882  C  CA  . GLN D 3 147 ? 14.603  -22.239 27.815 1   44.32  ? 388 GLN Q CA  1 
ATOM   5883  C  C   . GLN D 3 147 ? 13.745  -21.007 27.506 1   44.81  ? 388 GLN Q C   1 
ATOM   5884  O  O   . GLN D 3 147 ? 14.19   -19.884 27.805 1   42.79  ? 388 GLN Q O   1 
ATOM   5885  C  CB  . GLN D 3 147 ? 14.737  -22.365 29.337 1   46.37  ? 388 GLN Q CB  1 
ATOM   5886  C  CG  . GLN D 3 147 ? 13.429  -22.674 30.065 1   48.28  ? 388 GLN Q CG  1 
ATOM   5887  C  CD  . GLN D 3 147 ? 12.839  -24.035 29.767 1   51.56  ? 388 GLN Q CD  1 
ATOM   5888  O  OE1 . GLN D 3 147 ? 13.463  -24.902 29.155 1   57.44  ? 388 GLN Q OE1 1 
ATOM   5889  N  NE2 . GLN D 3 147 ? 11.616  -24.245 30.221 1   52.95  ? 388 GLN Q NE2 1 
ATOM   5890  N  N   . GLU D 3 148 ? 12.538  -21.223 26.981 1   44.45  ? 389 GLU Q N   1 
ATOM   5891  C  CA  . GLU D 3 148 ? 11.493  -20.178 26.853 1   43.77  ? 389 GLU Q CA  1 
ATOM   5892  C  C   . GLU D 3 148 ? 10.915  -19.866 28.235 1   44.16  ? 389 GLU Q C   1 
ATOM   5893  O  O   . GLU D 3 148 ? 10.484  -20.808 28.92  1   45.54  ? 389 GLU Q O   1 
ATOM   5894  C  CB  . GLU D 3 148 ? 10.38   -20.633 25.917 1   43.46  ? 389 GLU Q CB  1 
ATOM   5895  C  CG  . GLU D 3 148 ? 9.204   -19.68  25.883 1   44.05  ? 389 GLU Q CG  1 
ATOM   5896  C  CD  . GLU D 3 148 ? 8.313   -19.854 24.673 1   46.33  ? 389 GLU Q CD  1 
ATOM   5897  O  OE1 . GLU D 3 148 ? 7.646   -18.876 24.291 1   49.5   ? 389 GLU Q OE1 1 
ATOM   5898  O  OE2 . GLU D 3 148 ? 8.294   -20.968 24.115 1   48.79  ? 389 GLU Q OE2 1 
ATOM   5899  N  N   . LEU D 3 149 ? 10.866  -18.585 28.599 1   46.09  ? 390 LEU Q N   1 
ATOM   5900  C  CA  . LEU D 3 149 ? 10.258  -18.119 29.871 1   48.15  ? 390 LEU Q CA  1 
ATOM   5901  C  C   . LEU D 3 149 ? 8.749   -18.038 29.67  1   48.12  ? 390 LEU Q C   1 
ATOM   5902  O  O   . LEU D 3 149 ? 8.292   -17.645 28.6   1   47.01  ? 390 LEU Q O   1 
ATOM   5903  C  CB  . LEU D 3 149 ? 10.859  -16.766 30.268 1   49.13  ? 390 LEU Q CB  1 
ATOM   5904  C  CG  . LEU D 3 149 ? 12.384  -16.726 30.382 1   49.77  ? 390 LEU Q CG  1 
ATOM   5905  C  CD1 . LEU D 3 149 ? 12.85   -15.356 30.826 1   50.07  ? 390 LEU Q CD1 1 
ATOM   5906  C  CD2 . LEU D 3 149 ? 12.906  -17.783 31.345 1   51.15  ? 390 LEU Q CD2 1 
ATOM   5907  N  N   . PRO D 3 150 ? 7.927   -18.448 30.664 1   49.52  ? 391 PRO Q N   1 
ATOM   5908  C  CA  . PRO D 3 150 ? 6.478   -18.295 30.557 1   50.54  ? 391 PRO Q CA  1 
ATOM   5909  C  C   . PRO D 3 150 ? 6.066   -16.815 30.642 1   50.8   ? 391 PRO Q C   1 
ATOM   5910  O  O   . PRO D 3 150 ? 6.725   -16.068 31.351 1   46.8   ? 391 PRO Q O   1 
ATOM   5911  C  CB  . PRO D 3 150 ? 5.913   -19.126 31.724 1   51.53  ? 391 PRO Q CB  1 
ATOM   5912  C  CG  . PRO D 3 150 ? 7.059   -19.293 32.705 1   50.77  ? 391 PRO Q CG  1 
ATOM   5913  C  CD  . PRO D 3 150 ? 8.341   -19.083 31.925 1   50.7   ? 391 PRO Q CD  1 
ATOM   5914  N  N   . ARG D 3 151 ? 4.988   -16.453 29.931 1   52.84  ? 392 ARG Q N   1 
ATOM   5915  C  CA  . ARG D 3 151 ? 4.407   -15.082 29.817 1   55.23  ? 392 ARG Q CA  1 
ATOM   5916  C  C   . ARG D 3 151 ? 4.493   -14.337 31.154 1   55.75  ? 392 ARG Q C   1 
ATOM   5917  O  O   . ARG D 3 151 ? 4.903   -13.164 31.139 1   55.63  ? 392 ARG Q O   1 
ATOM   5918  C  CB  . ARG D 3 151 ? 2.944   -15.154 29.358 1   58.52  ? 392 ARG Q CB  1 
ATOM   5919  C  CG  . ARG D 3 151 ? 2.773   -15.444 27.872 1   63.23  ? 392 ARG Q CG  1 
ATOM   5920  C  CD  . ARG D 3 151 ? 1.321   -15.524 27.43  1   64.83  ? 392 ARG Q CD  1 
ATOM   5921  N  NE  . ARG D 3 151 ? 1.246   -15.835 25.987 0   64.03  ? 392 ARG Q NE  1 
ATOM   5922  C  CZ  . ARG D 3 151 ? 0.125   -15.871 25.268 0   64.07  ? 392 ARG Q CZ  1 
ATOM   5923  N  NH1 . ARG D 3 151 ? -1.052  -15.608 25.813 0   64.03  ? 392 ARG Q NH1 1 
ATOM   5924  N  NH2 . ARG D 3 151 ? 0.189   -16.174 23.983 0   64.05  ? 392 ARG Q NH2 1 
ATOM   5925  N  N   . GLU D 3 152 ? 4.158   -15.016 32.258 1   57.26  ? 393 GLU Q N   1 
ATOM   5926  C  CA  . GLU D 3 152 ? 4.044   -14.449 33.633 1   59.38  ? 393 GLU Q CA  1 
ATOM   5927  C  C   . GLU D 3 152 ? 5.382   -13.889 34.146 1   58.47  ? 393 GLU Q C   1 
ATOM   5928  O  O   . GLU D 3 152 ? 5.337   -13.128 35.123 1   58.46  ? 393 GLU Q O   1 
ATOM   5929  C  CB  . GLU D 3 152 ? 3.535   -15.513 34.61  1   62.26  ? 393 GLU Q CB  1 
ATOM   5930  C  CG  . GLU D 3 152 ? 2.085   -15.922 34.379 1   66.86  ? 393 GLU Q CG  1 
ATOM   5931  C  CD  . GLU D 3 152 ? 1.83    -17.054 33.39  1   70.1   ? 393 GLU Q CD  1 
ATOM   5932  O  OE1 . GLU D 3 152 ? 2.775   -17.835 33.104 1   66.48  ? 393 GLU Q OE1 1 
ATOM   5933  O  OE2 . GLU D 3 152 ? 0.677   -17.155 32.907 1   69.19  ? 393 GLU Q OE2 1 
ATOM   5934  N  N   . LYS D 3 153 ? 6.52    -14.258 33.544 1   58.4   ? 394 LYS Q N   1 
ATOM   5935  C  CA  . LYS D 3 153 ? 7.882   -13.872 34.011 1   61.19  ? 394 LYS Q CA  1 
ATOM   5936  C  C   . LYS D 3 153 ? 8.395   -12.603 33.307 1   57.84  ? 394 LYS Q C   1 
ATOM   5937  O  O   . LYS D 3 153 ? 9.529   -12.182 33.641 1   55.98  ? 394 LYS Q O   1 
ATOM   5938  C  CB  . LYS D 3 153 ? 8.854   -15.038 33.792 1   65.31  ? 394 LYS Q CB  1 
ATOM   5939  C  CG  . LYS D 3 153 ? 8.464   -16.352 34.463 1   70.02  ? 394 LYS Q CG  1 
ATOM   5940  C  CD  . LYS D 3 153 ? 8.264   -16.291 35.972 1   72.13  ? 394 LYS Q CD  1 
ATOM   5941  C  CE  . LYS D 3 153 ? 9.512   -15.916 36.745 1   74.91  ? 394 LYS Q CE  1 
ATOM   5942  N  NZ  . LYS D 3 153 ? 9.231   -15.777 38.194 1   77.38  ? 394 LYS Q NZ  1 
ATOM   5943  N  N   . TYR D 3 154 ? 7.628   -12.009 32.381 1   53.46  ? 395 TYR Q N   1 
ATOM   5944  C  CA  . TYR D 3 154 ? 7.997   -10.738 31.698 1   50.68  ? 395 TYR Q CA  1 
ATOM   5945  C  C   . TYR D 3 154 ? 6.758   -9.875  31.429 1   48.29  ? 395 TYR Q C   1 
ATOM   5946  O  O   . TYR D 3 154 ? 5.623   -10.368 31.53  1   46.52  ? 395 TYR Q O   1 
ATOM   5947  C  CB  . TYR D 3 154 ? 8.785   -11.005 30.413 1   49.8   ? 395 TYR Q CB  1 
ATOM   5948  C  CG  . TYR D 3 154 ? 8.121   -11.899 29.397 1   49.27  ? 395 TYR Q CG  1 
ATOM   5949  C  CD1 . TYR D 3 154 ? 7.296   -11.379 28.41  1   48.75  ? 395 TYR Q CD1 1 
ATOM   5950  C  CD2 . TYR D 3 154 ? 8.36    -13.265 29.386 1   48.47  ? 395 TYR Q CD2 1 
ATOM   5951  C  CE1 . TYR D 3 154 ? 6.706   -12.194 27.455 1   48.24  ? 395 TYR Q CE1 1 
ATOM   5952  C  CE2 . TYR D 3 154 ? 7.781   -14.093 28.439 1   47.51  ? 395 TYR Q CE2 1 
ATOM   5953  C  CZ  . TYR D 3 154 ? 6.955   -13.557 27.468 1   47.78  ? 395 TYR Q CZ  1 
ATOM   5954  O  OH  . TYR D 3 154 ? 6.38    -14.371 26.538 1   49.46  ? 395 TYR Q OH  1 
ATOM   5955  N  N   . LEU D 3 155 ? 7.003   -8.601  31.112 1   46.49  ? 396 LEU Q N   1 
ATOM   5956  C  CA  . LEU D 3 155 ? 5.97    -7.563  30.87  1   45.88  ? 396 LEU Q CA  1 
ATOM   5957  C  C   . LEU D 3 155 ? 6.129   -7.044  29.443 1   45.04  ? 396 LEU Q C   1 
ATOM   5958  O  O   . LEU D 3 155 ? 7.212   -6.508  29.139 1   45.98  ? 396 LEU Q O   1 
ATOM   5959  C  CB  . LEU D 3 155 ? 6.143   -6.434  31.892 1   46.31  ? 396 LEU Q CB  1 
ATOM   5960  C  CG  . LEU D 3 155 ? 5.338   -5.16   31.631 1   45.72  ? 396 LEU Q CG  1 
ATOM   5961  C  CD1 . LEU D 3 155 ? 3.851   -5.459  31.505 1   46.22  ? 396 LEU Q CD1 1 
ATOM   5962  C  CD2 . LEU D 3 155 ? 5.582   -4.141  32.728 1   45.41  ? 396 LEU Q CD2 1 
ATOM   5963  N  N   . THR D 3 156 ? 5.08    -7.186  28.627 1   45.07  ? 397 THR Q N   1 
ATOM   5964  C  CA  . THR D 3 156 ? 4.994   -6.683  27.231 1   44.83  ? 397 THR Q CA  1 
ATOM   5965  C  C   . THR D 3 156 ? 3.886   -5.624  27.151 1   44.06  ? 397 THR Q C   1 
ATOM   5966  O  O   . THR D 3 156 ? 2.751   -5.919  27.551 1   44.25  ? 397 THR Q O   1 
ATOM   5967  C  CB  . THR D 3 156 ? 4.762   -7.834  26.245 1   44.67  ? 397 THR Q CB  1 
ATOM   5968  O  OG1 . THR D 3 156 ? 5.792   -8.799  26.459 1   46.4   ? 397 THR Q OG1 1 
ATOM   5969  C  CG2 . THR D 3 156 ? 4.78    -7.401  24.795 1   44.99  ? 397 THR Q CG2 1 
ATOM   5970  N  N   . TRP D 3 157 ? 4.213   -4.439  26.632 1   44.7   ? 398 TRP Q N   1 
ATOM   5971  C  CA  . TRP D 3 157 ? 3.247   -3.343  26.346 1   43.07  ? 398 TRP Q CA  1 
ATOM   5972  C  C   . TRP D 3 157 ? 2.508   -3.659  25.043 1   43.71  ? 398 TRP Q C   1 
ATOM   5973  O  O   . TRP D 3 157 ? 2.933   -4.595  24.333 1   45.1   ? 398 TRP Q O   1 
ATOM   5974  C  CB  . TRP D 3 157 ? 3.967   -1.986  26.31  1   40.53  ? 398 TRP Q CB  1 
ATOM   5975  C  CG  . TRP D 3 157 ? 4.32    -1.511  27.682 1   37.56  ? 398 TRP Q CG  1 
ATOM   5976  C  CD1 . TRP D 3 157 ? 3.537   -0.758  28.504 1   37.73  ? 398 TRP Q CD1 1 
ATOM   5977  C  CD2 . TRP D 3 157 ? 5.503   -1.82   28.434 1   36.56  ? 398 TRP Q CD2 1 
ATOM   5978  N  NE1 . TRP D 3 157 ? 4.161   -0.556  29.705 1   36.91  ? 398 TRP Q NE1 1 
ATOM   5979  C  CE2 . TRP D 3 157 ? 5.371   -1.193  29.693 1   36.32  ? 398 TRP Q CE2 1 
ATOM   5980  C  CE3 . TRP D 3 157 ? 6.658   -2.563  28.176 1   36.47  ? 398 TRP Q CE3 1 
ATOM   5981  C  CZ2 . TRP D 3 157 ? 6.351   -1.278  30.681 1   35.57  ? 398 TRP Q CZ2 1 
ATOM   5982  C  CZ3 . TRP D 3 157 ? 7.628   -2.645  29.15  1   36.15  ? 398 TRP Q CZ3 1 
ATOM   5983  C  CH2 . TRP D 3 157 ? 7.475   -2.011  30.386 1   36.62  ? 398 TRP Q CH2 1 
ATOM   5984  N  N   . ALA D 3 158 ? 1.427   -2.932  24.755 1   43.45  ? 399 ALA Q N   1 
ATOM   5985  C  CA  . ALA D 3 158 ? 0.634   -3.089  23.515 1   45.48  ? 399 ALA Q CA  1 
ATOM   5986  C  C   . ALA D 3 158 ? 1.328   -2.326  22.385 1   46.13  ? 399 ALA Q C   1 
ATOM   5987  O  O   . ALA D 3 158 ? 1.948   -1.293  22.665 1   46.41  ? 399 ALA Q O   1 
ATOM   5988  C  CB  . ALA D 3 158 ? -0.781  -2.608  23.713 1   47.27  ? 399 ALA Q CB  1 
ATOM   5989  N  N   . SER D 3 159 ? 1.239   -2.843  21.16  1   46.32  ? 400 SER Q N   1 
ATOM   5990  C  CA  . SER D 3 159 ? 1.762   -2.201  19.93  1   47.9   ? 400 SER Q CA  1 
ATOM   5991  C  C   . SER D 3 159 ? 1.029   -0.868  19.724 1   47.37  ? 400 SER Q C   1 
ATOM   5992  O  O   . SER D 3 159 ? -0.215  -0.89   19.708 1   50.47  ? 400 SER Q O   1 
ATOM   5993  C  CB  . SER D 3 159 ? 1.614   -3.138  18.756 1   48.36  ? 400 SER Q CB  1 
ATOM   5994  O  OG  . SER D 3 159 ? 2.015   -2.522  17.542 1   50.9   ? 400 SER Q OG  1 
ATOM   5995  N  N   . ARG D 3 160 ? 1.767   0.245   19.623 1   48.19  ? 401 ARG Q N   1 
ATOM   5996  C  CA  . ARG D 3 160 ? 1.216   1.625   19.458 1   49.68  ? 401 ARG Q CA  1 
ATOM   5997  C  C   . ARG D 3 160 ? 1.88    2.297   18.249 1   49.71  ? 401 ARG Q C   1 
ATOM   5998  O  O   . ARG D 3 160 ? 3.058   2.006   17.986 1   46.64  ? 401 ARG Q O   1 
ATOM   5999  C  CB  . ARG D 3 160 ? 1.429   2.467   20.722 1   47.77  ? 401 ARG Q CB  1 
ATOM   6000  C  CG  . ARG D 3 160 ? 0.806   1.872   21.977 1   49.57  ? 401 ARG Q CG  1 
ATOM   6001  C  CD  . ARG D 3 160 ? 0.886   2.781   23.189 1   52.04  ? 401 ARG Q CD  1 
ATOM   6002  N  NE  . ARG D 3 160 ? -0.412  3.359   23.541 1   54.65  ? 401 ARG Q NE  1 
ATOM   6003  C  CZ  . ARG D 3 160 ? -1.218  2.96    24.532 1   55.64  ? 401 ARG Q CZ  1 
ATOM   6004  N  NH1 . ARG D 3 160 ? -0.898  1.95    25.328 1   57.79  ? 401 ARG Q NH1 1 
ATOM   6005  N  NH2 . ARG D 3 160 ? -2.364  3.59    24.726 1   59.05  ? 401 ARG Q NH2 1 
ATOM   6006  N  N   . GLN D 3 161 ? 1.138   3.162   17.549 1   53.64  ? 402 GLN Q N   1 
ATOM   6007  C  CA  . GLN D 3 161 ? 1.601   3.886   16.333 1   55.51  ? 402 GLN Q CA  1 
ATOM   6008  C  C   . GLN D 3 161 ? 2.724   4.858   16.71  1   55.22  ? 402 GLN Q C   1 
ATOM   6009  O  O   . GLN D 3 161 ? 2.573   5.566   17.729 1   50.58  ? 402 GLN Q O   1 
ATOM   6010  C  CB  . GLN D 3 161 ? 0.44    4.637   15.677 1   59.52  ? 402 GLN Q CB  1 
ATOM   6011  C  CG  . GLN D 3 161 ? 0.779   5.202   14.303 1   61.75  ? 402 GLN Q CG  1 
ATOM   6012  C  CD  . GLN D 3 161 ? -0.417  5.792   13.592 1   64.22  ? 402 GLN Q CD  1 
ATOM   6013  O  OE1 . GLN D 3 161 ? -1.561  5.397   13.813 1   64.27  ? 402 GLN Q OE1 1 
ATOM   6014  N  NE2 . GLN D 3 161 ? -0.158  6.741   12.706 1   68.13  ? 402 GLN Q NE2 1 
ATOM   6015  N  N   . GLU D 3 162 ? 3.795   4.885   15.908 1   57.52  ? 403 GLU Q N   1 
ATOM   6016  C  CA  . GLU D 3 162 ? 4.969   5.786   16.079 1   59.76  ? 403 GLU Q CA  1 
ATOM   6017  C  C   . GLU D 3 162 ? 4.683   7.141   15.432 1   63.73  ? 403 GLU Q C   1 
ATOM   6018  O  O   . GLU D 3 162 ? 3.86    7.225   14.52  1   63.2   ? 403 GLU Q O   1 
ATOM   6019  C  CB  . GLU D 3 162 ? 6.22    5.197   15.426 1   58.77  ? 403 GLU Q CB  1 
ATOM   6020  C  CG  . GLU D 3 162 ? 6.766   3.963   16.114 1   57.84  ? 403 GLU Q CG  1 
ATOM   6021  C  CD  . GLU D 3 162 ? 8.141   3.571   15.599 1   56.56  ? 403 GLU Q CD  1 
ATOM   6022  O  OE1 . GLU D 3 162 ? 8.221   3.025   14.482 1   54.24  ? 403 GLU Q OE1 1 
ATOM   6023  O  OE2 . GLU D 3 162 ? 9.132   3.852   16.299 1   55.31  ? 403 GLU Q OE2 1 
ATOM   6024  N  N   . PRO D 3 163 ? 5.353   8.238   15.866 1   67.13  ? 404 PRO Q N   1 
ATOM   6025  C  CA  . PRO D 3 163 ? 5.323   9.502   15.127 1   69.93  ? 404 PRO Q CA  1 
ATOM   6026  C  C   . PRO D 3 163 ? 5.966   9.394   13.735 1   75.54  ? 404 PRO Q C   1 
ATOM   6027  O  O   . PRO D 3 163 ? 7.064   8.865   13.648 1   71.92  ? 404 PRO Q O   1 
ATOM   6028  C  CB  . PRO D 3 163 ? 6.139   10.472  15.997 1   69.71  ? 404 PRO Q CB  1 
ATOM   6029  C  CG  . PRO D 3 163 ? 6.152   9.84    17.371 1   69.1   ? 404 PRO Q CG  1 
ATOM   6030  C  CD  . PRO D 3 163 ? 6.125   8.349   17.114 1   66.47  ? 404 PRO Q CD  1 
ATOM   6031  N  N   . SER D 3 164 ? 5.268   9.884   12.703 1   82.15  ? 405 SER Q N   1 
ATOM   6032  C  CA  . SER D 3 164 ? 5.774   10.055  11.312 1   87.25  ? 405 SER Q CA  1 
ATOM   6033  C  C   . SER D 3 164 ? 4.738   10.797  10.458 1   94.83  ? 405 SER Q C   1 
ATOM   6034  O  O   . SER D 3 164 ? 3.548   10.426  10.519 1   93.76  ? 405 SER Q O   1 
ATOM   6035  C  CB  . SER D 3 164 ? 6.127   8.732   10.675 1   90.19  ? 405 SER Q CB  1 
ATOM   6036  O  OG  . SER D 3 164 ? 6.574   8.917   9.337  1   91.04  ? 405 SER Q OG  1 
ATOM   6037  N  N   . GLN D 3 165 ? 5.188   11.797  9.692  1   103.46 ? 406 GLN Q N   1 
ATOM   6038  C  CA  . GLN D 3 165 ? 4.424   12.42   8.575  1   104.58 ? 406 GLN Q CA  1 
ATOM   6039  C  C   . GLN D 3 165 ? 4.377   11.442  7.39   1   105.31 ? 406 GLN Q C   1 
ATOM   6040  O  O   . GLN D 3 165 ? 3.385   11.496  6.632  1   106.94 ? 406 GLN Q O   1 
ATOM   6041  C  CB  . GLN D 3 165 ? 5.052   13.754  8.154  1   105.62 ? 406 GLN Q CB  1 
ATOM   6042  C  CG  . GLN D 3 165 ? 4.959   14.845  9.212  1   101.62 ? 406 GLN Q CG  1 
ATOM   6043  C  CD  . GLN D 3 165 ? 5.543   16.158  8.77   0   105.62 ? 406 GLN Q CD  1 
ATOM   6044  O  OE1 . GLN D 3 165 ? 6.311   16.233  7.813  0   105.39 ? 406 GLN Q OE1 1 
ATOM   6045  N  NE2 . GLN D 3 165 ? 5.183   17.223  9.471  0   105.56 ? 406 GLN Q NE2 1 
ATOM   6046  N  N   . GLY D 3 166 ? 5.404   10.589  7.243  1   102.25 ? 407 GLY Q N   1 
ATOM   6047  C  CA  . GLY D 3 166 ? 5.549   9.604   6.151  1   98.27  ? 407 GLY Q CA  1 
ATOM   6048  C  C   . GLY D 3 166 ? 4.703   8.359   6.376  1   95.12  ? 407 GLY Q C   1 
ATOM   6049  O  O   . GLY D 3 166 ? 3.477   8.506   6.559  1   94.71  ? 407 GLY Q O   1 
ATOM   6050  N  N   . THR D 3 167 ? 5.328   7.174   6.359  1   89.34  ? 408 THR Q N   1 
ATOM   6051  C  CA  . THR D 3 167 ? 4.648   5.849   6.432  1   88.27  ? 408 THR Q CA  1 
ATOM   6052  C  C   . THR D 3 167 ? 4.186   5.562   7.866  1   83.75  ? 408 THR Q C   1 
ATOM   6053  O  O   . THR D 3 167 ? 4.866   6.009   8.816  1   83.33  ? 408 THR Q O   1 
ATOM   6054  C  CB  . THR D 3 167 ? 5.55    4.713   5.929  1   91.79  ? 408 THR Q CB  1 
ATOM   6055  O  OG1 . THR D 3 167 ? 6.765   4.723   6.683  1   92.4   ? 408 THR Q OG1 1 
ATOM   6056  C  CG2 . THR D 3 167 ? 5.856   4.812   4.45   1   92.04  ? 408 THR Q CG2 1 
ATOM   6057  N  N   . THR D 3 168 ? 3.078   4.827   8.004  1   76.19  ? 409 THR Q N   1 
ATOM   6058  C  CA  . THR D 3 168 ? 2.462   4.437   9.3    1   70.41  ? 409 THR Q CA  1 
ATOM   6059  C  C   . THR D 3 168 ? 3.135   3.155   9.802  1   66.23  ? 409 THR Q C   1 
ATOM   6060  O  O   . THR D 3 168 ? 2.811   2.071   9.269  1   66.45  ? 409 THR Q O   1 
ATOM   6061  C  CB  . THR D 3 168 ? 0.942   4.274   9.166  1   71.46  ? 409 THR Q CB  1 
ATOM   6062  O  OG1 . THR D 3 168 ? 0.419   5.466   8.582  1   72.73  ? 409 THR Q OG1 1 
ATOM   6063  C  CG2 . THR D 3 168 ? 0.255   4.018   10.489 1   72.62  ? 409 THR Q CG2 1 
ATOM   6064  N  N   . THR D 3 169 ? 4.047   3.286   10.77  1   61.57  ? 410 THR Q N   1 
ATOM   6065  C  CA  . THR D 3 169 ? 4.723   2.165   11.479 1   59.05  ? 410 THR Q CA  1 
ATOM   6066  C  C   . THR D 3 169 ? 4.217   2.078   12.922 1   58.34  ? 410 THR Q C   1 
ATOM   6067  O  O   . THR D 3 169 ? 3.642   3.067   13.422 1   57.38  ? 410 THR Q O   1 
ATOM   6068  C  CB  . THR D 3 169 ? 6.25    2.317   11.497 1   58.33  ? 410 THR Q CB  1 
ATOM   6069  O  OG1 . THR D 3 169 ? 6.593   3.411   12.349 1   57.23  ? 410 THR Q OG1 1 
ATOM   6070  C  CG2 . THR D 3 169 ? 6.854   2.516   10.122 1   57.83  ? 410 THR Q CG2 1 
ATOM   6071  N  N   . PHE D 3 170 ? 4.453   0.931   13.56  1   57.73  ? 411 PHE Q N   1 
ATOM   6072  C  CA  . PHE D 3 170 ? 4.145   0.655   14.986 1   54.27  ? 411 PHE Q CA  1 
ATOM   6073  C  C   . PHE D 3 170 ? 5.425   0.231   15.712 1   50.8   ? 411 PHE Q C   1 
ATOM   6074  O  O   . PHE D 3 170 ? 6.423   -0.155  15.066 1   50.84  ? 411 PHE Q O   1 
ATOM   6075  C  CB  . PHE D 3 170 ? 3.041   -0.395  15.09  1   54.51  ? 411 PHE Q CB  1 
ATOM   6076  C  CG  . PHE D 3 170 ? 1.708   0.073   14.563 1   58.93  ? 411 PHE Q CG  1 
ATOM   6077  C  CD1 . PHE D 3 170 ? 1.43    0.047   13.202 1   59.34  ? 411 PHE Q CD1 1 
ATOM   6078  C  CD2 . PHE D 3 170 ? 0.729   0.544   15.426 1   58.82  ? 411 PHE Q CD2 1 
ATOM   6079  C  CE1 . PHE D 3 170 ? 0.202   0.481   12.719 1   58.87  ? 411 PHE Q CE1 1 
ATOM   6080  C  CE2 . PHE D 3 170 ? -0.499  0.974   14.94  1   60.28  ? 411 PHE Q CE2 1 
ATOM   6081  C  CZ  . PHE D 3 170 ? -0.759  0.943   13.587 1   59.55  ? 411 PHE Q CZ  1 
ATOM   6082  N  N   . ALA D 3 171 ? 5.395   0.345   17.037 1   46.52  ? 412 ALA Q N   1 
ATOM   6083  C  CA  . ALA D 3 171 ? 6.475   -0.067  17.956 1   44.57  ? 412 ALA Q CA  1 
ATOM   6084  C  C   . ALA D 3 171 ? 5.86    -0.76   19.175 1   44.16  ? 412 ALA Q C   1 
ATOM   6085  O  O   . ALA D 3 171 ? 4.748   -0.379  19.584 1   46.25  ? 412 ALA Q O   1 
ATOM   6086  C  CB  . ALA D 3 171 ? 7.287   1.135   18.357 1   44.36  ? 412 ALA Q CB  1 
ATOM   6087  N  N   . VAL D 3 172 ? 6.564   -1.746  19.726 1   42.14  ? 413 VAL Q N   1 
ATOM   6088  C  CA  . VAL D 3 172 ? 6.204   -2.417  21.005 1   41.61  ? 413 VAL Q CA  1 
ATOM   6089  C  C   . VAL D 3 172 ? 7.486   -2.596  21.824 1   40.94  ? 413 VAL Q C   1 
ATOM   6090  O  O   . VAL D 3 172 ? 8.577   -2.709  21.228 1   43.04  ? 413 VAL Q O   1 
ATOM   6091  C  CB  . VAL D 3 172 ? 5.459   -3.743  20.748 1   43.29  ? 413 VAL Q CB  1 
ATOM   6092  C  CG1 . VAL D 3 172 ? 6.35    -4.824  20.161 1   43.33  ? 413 VAL Q CG1 1 
ATOM   6093  C  CG2 . VAL D 3 172 ? 4.767   -4.251  21.998 1   44.32  ? 413 VAL Q CG2 1 
ATOM   6094  N  N   . THR D 3 173 ? 7.351   -2.582  23.146 1   41.02  ? 414 THR Q N   1 
ATOM   6095  C  CA  . THR D 3 173 ? 8.445   -2.809  24.122 1   40.47  ? 414 THR Q CA  1 
ATOM   6096  C  C   . THR D 3 173 ? 8.073   -4.005  25.002 1   41.35  ? 414 THR Q C   1 
ATOM   6097  O  O   . THR D 3 173 ? 6.865   -4.288  25.165 1   41.44  ? 414 THR Q O   1 
ATOM   6098  C  CB  . THR D 3 173 ? 8.727   -1.545  24.942 1   39.28  ? 414 THR Q CB  1 
ATOM   6099  O  OG1 . THR D 3 173 ? 7.502   -1.111  25.532 1   38.53  ? 414 THR Q OG1 1 
ATOM   6100  C  CG2 . THR D 3 173 ? 9.313   -0.433  24.1   1   39.03  ? 414 THR Q CG2 1 
ATOM   6101  N  N   . SER D 3 174 ? 9.087   -4.691  25.52  1   42.17  ? 415 SER Q N   1 
ATOM   6102  C  CA  . SER D 3 174 ? 8.952   -5.805  26.488 1   42.84  ? 415 SER Q CA  1 
ATOM   6103  C  C   . SER D 3 174 ? 10.157  -5.791  27.425 1   42.62  ? 415 SER Q C   1 
ATOM   6104  O  O   . SER D 3 174 ? 11.256  -5.407  26.985 1   41.39  ? 415 SER Q O   1 
ATOM   6105  C  CB  . SER D 3 174 ? 8.803   -7.132  25.793 1   43.48  ? 415 SER Q CB  1 
ATOM   6106  O  OG  . SER D 3 174 ? 8.271   -8.105  26.678 1   41.91  ? 415 SER Q OG  1 
ATOM   6107  N  N   . ILE D 3 175 ? 9.93    -6.202  28.669 1   45.07  ? 416 ILE Q N   1 
ATOM   6108  C  CA  . ILE D 3 175 ? 10.853  -6.004  29.822 1   45.22  ? 416 ILE Q CA  1 
ATOM   6109  C  C   . ILE D 3 175 ? 10.931  -7.337  30.575 1   43.69  ? 416 ILE Q C   1 
ATOM   6110  O  O   . ILE D 3 175 ? 9.879   -7.806  31.05  1   42.49  ? 416 ILE Q O   1 
ATOM   6111  C  CB  . ILE D 3 175 ? 10.332  -4.81   30.657 1   47.96  ? 416 ILE Q CB  1 
ATOM   6112  C  CG1 . ILE D 3 175 ? 10.782  -3.479  30.043 1   49.49  ? 416 ILE Q CG1 1 
ATOM   6113  C  CG2 . ILE D 3 175 ? 10.682  -4.899  32.136 1   48.39  ? 416 ILE Q CG2 1 
ATOM   6114  C  CD1 . ILE D 3 175 ? 12.225  -3.118  30.27  1   51.2   ? 416 ILE Q CD1 1 
ATOM   6115  N  N   . LEU D 3 176 ? 12.12   -7.945  30.618 1   45.05  ? 417 LEU Q N   1 
ATOM   6116  C  CA  . LEU D 3 176 ? 12.421  -9.187  31.382 1   44.11  ? 417 LEU Q CA  1 
ATOM   6117  C  C   . LEU D 3 176 ? 13.388  -8.844  32.522 1   44.45  ? 417 LEU Q C   1 
ATOM   6118  O  O   . LEU D 3 176 ? 14.512  -8.373  32.23  1   42.49  ? 417 LEU Q O   1 
ATOM   6119  C  CB  . LEU D 3 176 ? 13.017  -10.241 30.44  1   43.15  ? 417 LEU Q CB  1 
ATOM   6120  C  CG  . LEU D 3 176 ? 13.622  -11.471 31.121 1   42.08  ? 417 LEU Q CG  1 
ATOM   6121  C  CD1 . LEU D 3 176 ? 12.593  -12.209 31.969 1   41.34  ? 417 LEU Q CD1 1 
ATOM   6122  C  CD2 . LEU D 3 176 ? 14.249  -12.407 30.107 1   41.65  ? 417 LEU Q CD2 1 
ATOM   6123  N  N   . ARG D 3 177 ? 12.964  -9.084  33.766 1   46.21  ? 418 ARG Q N   1 
ATOM   6124  C  CA  . ARG D 3 177 ? 13.788  -8.89   34.987 1   48.59  ? 418 ARG Q CA  1 
ATOM   6125  C  C   . ARG D 3 177 ? 14.396  -10.239 35.388 1   52.86  ? 418 ARG Q C   1 
ATOM   6126  O  O   . ARG D 3 177 ? 13.638  -11.225 35.542 1   51.81  ? 418 ARG Q O   1 
ATOM   6127  C  CB  . ARG D 3 177 ? 12.949  -8.265  36.103 1   49     ? 418 ARG Q CB  1 
ATOM   6128  C  CG  . ARG D 3 177 ? 12.288  -6.951  35.706 1   49.09  ? 418 ARG Q CG  1 
ATOM   6129  C  CD  . ARG D 3 177 ? 12.109  -6.047  36.905 1   47.77  ? 418 ARG Q CD  1 
ATOM   6130  N  NE  . ARG D 3 177 ? 13.361  -5.367  37.218 1   48.21  ? 418 ARG Q NE  1 
ATOM   6131  C  CZ  . ARG D 3 177 ? 13.839  -5.105  38.439 1   48.21  ? 418 ARG Q CZ  1 
ATOM   6132  N  NH1 . ARG D 3 177 ? 13.192  -5.472  39.537 1   47.3   ? 418 ARG Q NH1 1 
ATOM   6133  N  NH2 . ARG D 3 177 ? 14.997  -4.473  38.554 1   48.66  ? 418 ARG Q NH2 1 
ATOM   6134  N  N   . VAL D 3 178 ? 15.724  -10.274 35.517 1   55.72  ? 419 VAL Q N   1 
ATOM   6135  C  CA  . VAL D 3 178 ? 16.529  -11.502 35.782 1   56.71  ? 419 VAL Q CA  1 
ATOM   6136  C  C   . VAL D 3 178 ? 17.548  -11.186 36.877 1   59.45  ? 419 VAL Q C   1 
ATOM   6137  O  O   . VAL D 3 178 ? 17.979  -10.021 36.964 1   60.4   ? 419 VAL Q O   1 
ATOM   6138  C  CB  . VAL D 3 178 ? 17.213  -12.008 34.499 1   56.53  ? 419 VAL Q CB  1 
ATOM   6139  C  CG1 . VAL D 3 178 ? 16.182  -12.396 33.456 1   57.65  ? 419 VAL Q CG1 1 
ATOM   6140  C  CG2 . VAL D 3 178 ? 18.199  -11.003 33.921 1   56.62  ? 419 VAL Q CG2 1 
ATOM   6141  N  N   . ALA D 3 179 ? 17.913  -12.201 37.661 1   63.26  ? 420 ALA Q N   1 
ATOM   6142  C  CA  . ALA D 3 179 ? 18.905  -12.126 38.759 1   63.29  ? 420 ALA Q CA  1 
ATOM   6143  C  C   . ALA D 3 179 ? 20.242  -11.621 38.206 1   63.74  ? 420 ALA Q C   1 
ATOM   6144  O  O   . ALA D 3 179 ? 20.651  -12.091 37.119 1   63.25  ? 420 ALA Q O   1 
ATOM   6145  C  CB  . ALA D 3 179 ? 19.056  -13.48  39.408 1   64.71  ? 420 ALA Q CB  1 
ATOM   6146  N  N   . ALA D 3 180 ? 20.879  -10.691 38.926 1   64.79  ? 421 ALA Q N   1 
ATOM   6147  C  CA  . ALA D 3 180 ? 22.242  -10.177 38.65  1   63.32  ? 421 ALA Q CA  1 
ATOM   6148  C  C   . ALA D 3 180 ? 23.217  -11.353 38.524 1   63.91  ? 421 ALA Q C   1 
ATOM   6149  O  O   . ALA D 3 180 ? 24.033  -11.319 37.583 1   63.13  ? 421 ALA Q O   1 
ATOM   6150  C  CB  . ALA D 3 180 ? 22.674  -9.221  39.736 1   62.46  ? 421 ALA Q CB  1 
ATOM   6151  N  N   . GLU D 3 181 ? 23.122  -12.339 39.433 1   65.14  ? 422 GLU Q N   1 
ATOM   6152  C  CA  . GLU D 3 181 ? 23.904  -13.611 39.42  1   67.86  ? 422 GLU Q CA  1 
ATOM   6153  C  C   . GLU D 3 181 ? 23.906  -14.192 38.002 1   64.76  ? 422 GLU Q C   1 
ATOM   6154  O  O   . GLU D 3 181 ? 24.998  -14.29  37.404 1   63.51  ? 422 GLU Q O   1 
ATOM   6155  C  CB  . GLU D 3 181 ? 23.309  -14.656 40.369 1   73.1   ? 422 GLU Q CB  1 
ATOM   6156  C  CG  . GLU D 3 181 ? 23.573  -14.392 41.838 1   79.74  ? 422 GLU Q CG  1 
ATOM   6157  C  CD  . GLU D 3 181 ? 22.836  -15.342 42.77  1   83.71  ? 422 GLU Q CD  1 
ATOM   6158  O  OE1 . GLU D 3 181 ? 23.203  -16.538 42.81  1   82.24  ? 422 GLU Q OE1 1 
ATOM   6159  O  OE2 . GLU D 3 181 ? 21.884  -14.888 43.441 1   86.14  ? 422 GLU Q OE2 1 
ATOM   6160  N  N   . ASP D 3 182 ? 22.712  -14.509 37.488 1   59.48  ? 423 ASP Q N   1 
ATOM   6161  C  CA  . ASP D 3 182 ? 22.491  -15.17  36.173 1   56.25  ? 423 ASP Q CA  1 
ATOM   6162  C  C   . ASP D 3 182 ? 23.192  -14.35  35.084 1   54.62  ? 423 ASP Q C   1 
ATOM   6163  O  O   . ASP D 3 182 ? 23.968  -14.947 34.318 1   56.53  ? 423 ASP Q O   1 
ATOM   6164  C  CB  . ASP D 3 182 ? 20.996  -15.37  35.888 1   54.75  ? 423 ASP Q CB  1 
ATOM   6165  C  CG  . ASP D 3 182 ? 20.283  -16.325 36.837 1   53.34  ? 423 ASP Q CG  1 
ATOM   6166  O  OD1 . ASP D 3 182 ? 20.913  -16.778 37.82  1   53.64  ? 423 ASP Q OD1 1 
ATOM   6167  O  OD2 . ASP D 3 182 ? 19.101  -16.609 36.59  1   49.43  ? 423 ASP Q OD2 1 
ATOM   6168  N  N   . TRP D 3 183 ? 22.961  -13.034 35.045 1   53.12  ? 424 TRP Q N   1 
ATOM   6169  C  CA  . TRP D 3 183 ? 23.588  -12.109 34.06  1   54.52  ? 424 TRP Q CA  1 
ATOM   6170  C  C   . TRP D 3 183 ? 25.118  -12.161 34.185 1   57.5   ? 424 TRP Q C   1 
ATOM   6171  O  O   . TRP D 3 183 ? 25.792  -12.147 33.13  1   56.91  ? 424 TRP Q O   1 
ATOM   6172  C  CB  . TRP D 3 183 ? 23.064  -10.673 34.216 1   52.65  ? 424 TRP Q CB  1 
ATOM   6173  C  CG  . TRP D 3 183 ? 23.764  -9.698  33.319 1   49.66  ? 424 TRP Q CG  1 
ATOM   6174  C  CD1 . TRP D 3 183 ? 24.844  -8.924  33.631 1   49.76  ? 424 TRP Q CD1 1 
ATOM   6175  C  CD2 . TRP D 3 183 ? 23.473  -9.437  31.935 1   47.95  ? 424 TRP Q CD2 1 
ATOM   6176  N  NE1 . TRP D 3 183 ? 25.23   -8.186  32.546 1   49.56  ? 424 TRP Q NE1 1 
ATOM   6177  C  CE2 . TRP D 3 183 ? 24.41   -8.48   31.49  1   48.63  ? 424 TRP Q CE2 1 
ATOM   6178  C  CE3 . TRP D 3 183 ? 22.514  -9.908  31.032 1   48.23  ? 424 TRP Q CE3 1 
ATOM   6179  C  CZ2 . TRP D 3 183 ? 24.407  -7.988  30.183 1   48.33  ? 424 TRP Q CZ2 1 
ATOM   6180  C  CZ3 . TRP D 3 183 ? 22.513  -9.423  29.743 1   47.32  ? 424 TRP Q CZ3 1 
ATOM   6181  C  CH2 . TRP D 3 183 ? 23.447  -8.474  29.325 1   46.62  ? 424 TRP Q CH2 1 
ATOM   6182  N  N   . LYS D 3 184 ? 25.636  -12.211 35.418 1   61.77  ? 425 LYS Q N   1 
ATOM   6183  C  CA  . LYS D 3 184 ? 27.095  -12.161 35.719 1   65.76  ? 425 LYS Q CA  1 
ATOM   6184  C  C   . LYS D 3 184 ? 27.762  -13.517 35.416 1   65.86  ? 425 LYS Q C   1 
ATOM   6185  O  O   . LYS D 3 184 ? 28.961  -13.489 35.066 1   65.72  ? 425 LYS Q O   1 
ATOM   6186  C  CB  . LYS D 3 184 ? 27.351  -11.699 37.162 1   69.21  ? 425 LYS Q CB  1 
ATOM   6187  C  CG  . LYS D 3 184 ? 27.576  -10.199 37.34  1   68.6   ? 425 LYS Q CG  1 
ATOM   6188  C  CD  . LYS D 3 184 ? 26.387  -9.363  37.529 0   68.1   ? 425 LYS Q CD  1 
ATOM   6189  C  CE  . LYS D 3 184 ? 26.696  -7.892  37.705 0   68.1   ? 425 LYS Q CE  1 
ATOM   6190  N  NZ  . LYS D 3 184 ? 25.555  -7.167  38.309 0   68.04  ? 425 LYS Q NZ  1 
ATOM   6191  N  N   . LYS D 3 185 ? 27.042  -14.649 35.529 1   63.56  ? 426 LYS Q N   1 
ATOM   6192  C  CA  . LYS D 3 185 ? 27.548  -16.005 35.154 1   60.27  ? 426 LYS Q CA  1 
ATOM   6193  C  C   . LYS D 3 185 ? 27.842  -16.082 33.65  1   58.54  ? 426 LYS Q C   1 
ATOM   6194  O  O   . LYS D 3 185 ? 28.575  -17.009 33.256 1   65.22  ? 426 LYS Q O   1 
ATOM   6195  C  CB  . LYS D 3 185 ? 26.54   -17.144 35.337 1   62.53  ? 426 LYS Q CB  1 
ATOM   6196  C  CG  . LYS D 3 185 ? 25.902  -17.35  36.698 1   66.81  ? 426 LYS Q CG  1 
ATOM   6197  C  CD  . LYS D 3 185 ? 24.884  -18.471 36.627 1   69.54  ? 426 LYS Q CD  1 
ATOM   6198  C  CE  . LYS D 3 185 ? 24.086  -18.673 37.896 1   73.98  ? 426 LYS Q CE  1 
ATOM   6199  N  NZ  . LYS D 3 185 ? 23.24   -19.887 37.807 1   76.01  ? 426 LYS Q NZ  1 
ATOM   6200  N  N   . GLY D 3 186 ? 27.194  -15.237 32.841 1   53.32  ? 427 GLY Q N   1 
ATOM   6201  C  CA  . GLY D 3 186 ? 27.314  -15.212 31.371 1   52.01  ? 427 GLY Q CA  1 
ATOM   6202  C  C   . GLY D 3 186 ? 26.133  -15.859 30.663 1   51.19  ? 427 GLY Q C   1 
ATOM   6203  O  O   . GLY D 3 186 ? 26.269  -16.135 29.451 1   49.06  ? 427 GLY Q O   1 
ATOM   6204  N  N   . ASP D 3 187 ? 25.008  -16.078 31.36  1   49.31  ? 428 ASP Q N   1 
ATOM   6205  C  CA  . ASP D 3 187 ? 23.764  -16.644 30.769 1   48.71  ? 428 ASP Q CA  1 
ATOM   6206  C  C   . ASP D 3 187 ? 23.334  -15.771 29.586 1   47.87  ? 428 ASP Q C   1 
ATOM   6207  O  O   . ASP D 3 187 ? 23.546  -14.545 29.64  1   49.63  ? 428 ASP Q O   1 
ATOM   6208  C  CB  . ASP D 3 187 ? 22.627  -16.753 31.793 1   48.52  ? 428 ASP Q CB  1 
ATOM   6209  C  CG  . ASP D 3 187 ? 22.747  -17.928 32.752 1   48.89  ? 428 ASP Q CG  1 
ATOM   6210  O  OD1 . ASP D 3 187 ? 23.842  -18.541 32.806 1   49.77  ? 428 ASP Q OD1 1 
ATOM   6211  O  OD2 . ASP D 3 187 ? 21.738  -18.231 33.434 1   46.84  ? 428 ASP Q OD2 1 
ATOM   6212  N  N   . THR D 3 188 ? 22.777  -16.39  28.546 1   47.55  ? 429 THR Q N   1 
ATOM   6213  C  CA  . THR D 3 188 ? 22.206  -15.687 27.369 1   45.9   ? 429 THR Q CA  1 
ATOM   6214  C  C   . THR D 3 188 ? 20.748  -15.347 27.68  1   44.77  ? 429 THR Q C   1 
ATOM   6215  O  O   . THR D 3 188 ? 20.108  -16.093 28.448 1   44.79  ? 429 THR Q O   1 
ATOM   6216  C  CB  . THR D 3 188 ? 22.343  -16.506 26.078 1   45.6   ? 429 THR Q CB  1 
ATOM   6217  O  OG1 . THR D 3 188 ? 21.552  -17.689 26.198 1   47     ? 429 THR Q OG1 1 
ATOM   6218  C  CG2 . THR D 3 188 ? 23.78   -16.858 25.761 1   44.86  ? 429 THR Q CG2 1 
ATOM   6219  N  N   . PHE D 3 189 ? 20.271  -14.228 27.141 1   43.53  ? 430 PHE Q N   1 
ATOM   6220  C  CA  . PHE D 3 189 ? 18.848  -13.817 27.168 1   41.81  ? 430 PHE Q CA  1 
ATOM   6221  C  C   . PHE D 3 189 ? 18.479  -13.371 25.756 1   40.78  ? 430 PHE Q C   1 
ATOM   6222  O  O   . PHE D 3 189 ? 19.277  -12.645 25.144 1   41.52  ? 430 PHE Q O   1 
ATOM   6223  C  CB  . PHE D 3 189 ? 18.626  -12.738 28.227 1   42.43  ? 430 PHE Q CB  1 
ATOM   6224  C  CG  . PHE D 3 189 ? 19.039  -13.152 29.616 1   41.96  ? 430 PHE Q CG  1 
ATOM   6225  C  CD1 . PHE D 3 189 ? 18.135  -13.759 30.474 1   42.26  ? 430 PHE Q CD1 1 
ATOM   6226  C  CD2 . PHE D 3 189 ? 20.337  -12.951 30.061 1   41.97  ? 430 PHE Q CD2 1 
ATOM   6227  C  CE1 . PHE D 3 189 ? 18.522  -14.149 31.748 1   42.59  ? 430 PHE Q CE1 1 
ATOM   6228  C  CE2 . PHE D 3 189 ? 20.721  -13.342 31.336 1   41.96  ? 430 PHE Q CE2 1 
ATOM   6229  C  CZ  . PHE D 3 189 ? 19.812  -13.939 32.178 1   41.48  ? 430 PHE Q CZ  1 
ATOM   6230  N  N   . SER D 3 190 ? 17.355  -13.863 25.238 1   41.7   ? 431 SER Q N   1 
ATOM   6231  C  CA  . SER D 3 190 ? 16.843  -13.552 23.878 1   43.07  ? 431 SER Q CA  1 
ATOM   6232  C  C   . SER D 3 190 ? 15.413  -13.03  23.996 1   43.07  ? 431 SER Q C   1 
ATOM   6233  O  O   . SER D 3 190 ? 14.678  -13.52  24.873 1   42.34  ? 431 SER Q O   1 
ATOM   6234  C  CB  . SER D 3 190 ? 16.894  -14.752 22.952 1   44.12  ? 431 SER Q CB  1 
ATOM   6235  O  OG  . SER D 3 190 ? 18.159  -15.398 22.992 1   45     ? 431 SER Q OG  1 
ATOM   6236  N  N   . CYS D 3 191 ? 15.052  -12.057 23.161 1   44.9   ? 432 CYS Q N   1 
ATOM   6237  C  CA  . CYS D 3 191 ? 13.641  -11.742 22.833 1   47.8   ? 432 CYS Q CA  1 
ATOM   6238  C  C   . CYS D 3 191 ? 13.408  -12.141 21.37  1   47.53  ? 432 CYS Q C   1 
ATOM   6239  O  O   . CYS D 3 191 ? 14.282  -11.854 20.519 1   44.52  ? 432 CYS Q O   1 
ATOM   6240  C  CB  . CYS D 3 191 ? 13.274  -10.295 23.155 1   50.39  ? 432 CYS Q CB  1 
ATOM   6241  S  SG  . CYS D 3 191 ? 13.677  -9.098  21.86  1   55.54  ? 432 CYS Q SG  1 
ATOM   6242  N  N   . MET D 3 192 ? 12.309  -12.859 21.128 1   49.45  ? 433 MET Q N   1 
ATOM   6243  C  CA  . MET D 3 192 ? 11.85   -13.32  19.797 1   49.3   ? 433 MET Q CA  1 
ATOM   6244  C  C   . MET D 3 192 ? 10.604  -12.514 19.438 1   47.39  ? 433 MET Q C   1 
ATOM   6245  O  O   . MET D 3 192 ? 9.671   -12.479 20.266 1   45.26  ? 433 MET Q O   1 
ATOM   6246  C  CB  . MET D 3 192 ? 11.51   -14.812 19.825 1   52.85  ? 433 MET Q CB  1 
ATOM   6247  C  CG  . MET D 3 192 ? 12.727  -15.685 20.061 1   56.89  ? 433 MET Q CG  1 
ATOM   6248  S  SD  . MET D 3 192 ? 12.352  -17.448 19.984 1   57.57  ? 433 MET Q SD  1 
ATOM   6249  C  CE  . MET D 3 192 ? 11.368  -17.62  21.472 1   60.94  ? 433 MET Q CE  1 
ATOM   6250  N  N   . VAL D 3 193 ? 10.618  -11.872 18.271 1   45.22  ? 434 VAL Q N   1 
ATOM   6251  C  CA  . VAL D 3 193 ? 9.52    -10.989 17.787 1   46.57  ? 434 VAL Q CA  1 
ATOM   6252  C  C   . VAL D 3 193 ? 8.855   -11.696 16.604 1   45.83  ? 434 VAL Q C   1 
ATOM   6253  O  O   . VAL D 3 193 ? 9.547   -11.903 15.593 1   43.4   ? 434 VAL Q O   1 
ATOM   6254  C  CB  . VAL D 3 193 ? 10.057  -9.59   17.419 1   46.65  ? 434 VAL Q CB  1 
ATOM   6255  C  CG1 . VAL D 3 193 ? 8.981   -8.692  16.824 1   45.55  ? 434 VAL Q CG1 1 
ATOM   6256  C  CG2 . VAL D 3 193 ? 10.709  -8.913  18.619 1   45.88  ? 434 VAL Q CG2 1 
ATOM   6257  N  N   . GLY D 3 194 ? 7.579   -12.066 16.749 1   46.69  ? 435 GLY Q N   1 
ATOM   6258  C  CA  . GLY D 3 194 ? 6.748   -12.649 15.677 1   49.99  ? 435 GLY Q CA  1 
ATOM   6259  C  C   . GLY D 3 194 ? 6.011   -11.57  14.903 1   51.11  ? 435 GLY Q C   1 
ATOM   6260  O  O   . GLY D 3 194 ? 5.431   -10.68  15.552 1   53.98  ? 435 GLY Q O   1 
ATOM   6261  N  N   . HIS D 3 195 ? 6.02    -11.632 13.568 1   51.55  ? 436 HIS Q N   1 
ATOM   6262  C  CA  . HIS D 3 195 ? 5.352   -10.622 12.708 1   52.51  ? 436 HIS Q CA  1 
ATOM   6263  C  C   . HIS D 3 195 ? 5.124   -11.146 11.283 1   53.7   ? 436 HIS Q C   1 
ATOM   6264  O  O   . HIS D 3 195 ? 6.022   -11.826 10.755 1   51.61  ? 436 HIS Q O   1 
ATOM   6265  C  CB  . HIS D 3 195 ? 6.157   -9.32   12.728 1   54.21  ? 436 HIS Q CB  1 
ATOM   6266  C  CG  . HIS D 3 195 ? 5.475   -8.224  11.991 1   53.5   ? 436 HIS Q CG  1 
ATOM   6267  N  ND1 . HIS D 3 195 ? 4.332   -7.623  12.465 1   52.7   ? 436 HIS Q ND1 1 
ATOM   6268  C  CD2 . HIS D 3 195 ? 5.748   -7.654  10.803 1   52.49  ? 436 HIS Q CD2 1 
ATOM   6269  C  CE1 . HIS D 3 195 ? 3.935   -6.722  11.599 1   52.75  ? 436 HIS Q CE1 1 
ATOM   6270  N  NE2 . HIS D 3 195 ? 4.787   -6.721  10.568 1   52.75  ? 436 HIS Q NE2 1 
ATOM   6271  N  N   . GLU D 3 196 ? 3.974   -10.781 10.696 1   57.18  ? 437 GLU Q N   1 
ATOM   6272  C  CA  . GLU D 3 196 ? 3.462   -11.207 9.359  1   58.81  ? 437 GLU Q CA  1 
ATOM   6273  C  C   . GLU D 3 196 ? 4.48    -10.941 8.243  1   58.36  ? 437 GLU Q C   1 
ATOM   6274  O  O   . GLU D 3 196 ? 4.526   -11.75  7.3    1   62.28  ? 437 GLU Q O   1 
ATOM   6275  C  CB  . GLU D 3 196 ? 2.188   -10.44  8.993  1   62.24  ? 437 GLU Q CB  1 
ATOM   6276  C  CG  . GLU D 3 196 ? 0.972   -10.818 9.818  1   67.3   ? 437 GLU Q CG  1 
ATOM   6277  C  CD  . GLU D 3 196 ? -0.348  -10.343 9.23   1   69.35  ? 437 GLU Q CD  1 
ATOM   6278  O  OE1 . GLU D 3 196 ? -1.274  -11.184 9.094  1   64.93  ? 437 GLU Q OE1 1 
ATOM   6279  O  OE2 . GLU D 3 196 ? -0.455  -9.132  8.926  1   66.5   ? 437 GLU Q OE2 1 
ATOM   6280  N  N   . ALA D 3 197 ? 5.215   -9.828  8.328  1   58.36  ? 438 ALA Q N   1 
ATOM   6281  C  CA  . ALA D 3 197 ? 6.122   -9.3    7.277  1   59.14  ? 438 ALA Q CA  1 
ATOM   6282  C  C   . ALA D 3 197 ? 7.521   -9.925  7.362  1   57.99  ? 438 ALA Q C   1 
ATOM   6283  O  O   . ALA D 3 197 ? 8.306   -9.692  6.423  1   59.54  ? 438 ALA Q O   1 
ATOM   6284  C  CB  . ALA D 3 197 ? 6.208   -7.794  7.371  1   58.4   ? 438 ALA Q CB  1 
ATOM   6285  N  N   . LEU D 3 198 ? 7.841   -10.664 8.43   1   57.65  ? 439 LEU Q N   1 
ATOM   6286  C  CA  . LEU D 3 198 ? 9.162   -11.334 8.581  1   57.87  ? 439 LEU Q CA  1 
ATOM   6287  C  C   . LEU D 3 198 ? 9.216   -12.555 7.665  1   58.9   ? 439 LEU Q C   1 
ATOM   6288  O  O   . LEU D 3 198 ? 8.317   -13.393 7.709  1   58.06  ? 439 LEU Q O   1 
ATOM   6289  C  CB  . LEU D 3 198 ? 9.395   -11.722 10.045 1   56.2   ? 439 LEU Q CB  1 
ATOM   6290  C  CG  . LEU D 3 198 ? 9.7     -10.56  10.988 1   55.19  ? 439 LEU Q CG  1 
ATOM   6291  C  CD1 . LEU D 3 198 ? 9.754   -11.037 12.43  1   54.79  ? 439 LEU Q CD1 1 
ATOM   6292  C  CD2 . LEU D 3 198 ? 11.002  -9.867  10.607 1   53.54  ? 439 LEU Q CD2 1 
ATOM   6293  N  N   . PRO D 3 199 ? 10.264  -12.702 6.816  1   61.01  ? 440 PRO Q N   1 
ATOM   6294  C  CA  . PRO D 3 199 ? 10.359  -13.842 5.9    1   63.18  ? 440 PRO Q CA  1 
ATOM   6295  C  C   . PRO D 3 199 ? 10.544  -15.191 6.614  1   62.99  ? 440 PRO Q C   1 
ATOM   6296  O  O   . PRO D 3 199 ? 10.183  -16.194 6.036  1   63.57  ? 440 PRO Q O   1 
ATOM   6297  C  CB  . PRO D 3 199 ? 11.588  -13.523 5.032  1   63.35  ? 440 PRO Q CB  1 
ATOM   6298  C  CG  . PRO D 3 199 ? 12.426  -12.601 5.891  1   62.81  ? 440 PRO Q CG  1 
ATOM   6299  C  CD  . PRO D 3 199 ? 11.428  -11.806 6.707  1   61.49  ? 440 PRO Q CD  1 
ATOM   6300  N  N   . LEU D 3 200 ? 11.095  -15.177 7.833  1   65.27  ? 441 LEU Q N   1 
ATOM   6301  C  CA  . LEU D 3 200 ? 11.306  -16.377 8.687  1   64.85  ? 441 LEU Q CA  1 
ATOM   6302  C  C   . LEU D 3 200 ? 10.368  -16.339 9.906  1   62.77  ? 441 LEU Q C   1 
ATOM   6303  O  O   . LEU D 3 200 ? 10.726  -16.958 10.929 1   61.58  ? 441 LEU Q O   1 
ATOM   6304  C  CB  . LEU D 3 200 ? 12.777  -16.415 9.12   1   68.06  ? 441 LEU Q CB  1 
ATOM   6305  C  CG  . LEU D 3 200 ? 13.814  -16.312 8      1   70.57  ? 441 LEU Q CG  1 
ATOM   6306  C  CD1 . LEU D 3 200 ? 15.207  -16.111 8.58   1   70.47  ? 441 LEU Q CD1 1 
ATOM   6307  C  CD2 . LEU D 3 200 ? 13.781  -17.539 7.097  1   69.89  ? 441 LEU Q CD2 1 
ATOM   6308  N  N   . ALA D 3 201 ? 9.221   -15.647 9.815  1   58.69  ? 442 ALA Q N   1 
ATOM   6309  C  CA  . ALA D 3 201 ? 8.118   -15.637 10.813 1   56.53  ? 442 ALA Q CA  1 
ATOM   6310  C  C   . ALA D 3 201 ? 8.516   -14.881 12.089 1   53.6   ? 442 ALA Q C   1 
ATOM   6311  O  O   . ALA D 3 201 ? 7.727   -14.019 12.527 1   52.9   ? 442 ALA Q O   1 
ATOM   6312  C  CB  . ALA D 3 201 ? 7.674   -17.047 11.139 1   57.82  ? 442 ALA Q CB  1 
ATOM   6313  N  N   . PHE D 3 202 ? 9.648   -15.244 12.7   1   50.51  ? 443 PHE Q N   1 
ATOM   6314  C  CA  . PHE D 3 202 ? 10.217  -14.596 13.911 1   50.96  ? 443 PHE Q CA  1 
ATOM   6315  C  C   . PHE D 3 202 ? 11.6    -14.007 13.595 1   53     ? 443 PHE Q C   1 
ATOM   6316  O  O   . PHE D 3 202 ? 12.267  -14.451 12.644 1   56.67  ? 443 PHE Q O   1 
ATOM   6317  C  CB  . PHE D 3 202 ? 10.257  -15.597 15.068 1   49.16  ? 443 PHE Q CB  1 
ATOM   6318  C  CG  . PHE D 3 202 ? 8.903   -15.906 15.656 1   48.59  ? 443 PHE Q CG  1 
ATOM   6319  C  CD1 . PHE D 3 202 ? 8.049   -16.808 15.036 1   48.59  ? 443 PHE Q CD1 1 
ATOM   6320  C  CD2 . PHE D 3 202 ? 8.471   -15.278 16.817 1   47.09  ? 443 PHE Q CD2 1 
ATOM   6321  C  CE1 . PHE D 3 202 ? 6.795   -17.077 15.566 1   47.29  ? 443 PHE Q CE1 1 
ATOM   6322  C  CE2 . PHE D 3 202 ? 7.22    -15.553 17.348 1   46.44  ? 443 PHE Q CE2 1 
ATOM   6323  C  CZ  . PHE D 3 202 ? 6.382   -16.448 16.72  1   46.97  ? 443 PHE Q CZ  1 
ATOM   6324  N  N   . THR D 3 203 ? 11.985  -12.974 14.346 1   54     ? 444 THR Q N   1 
ATOM   6325  C  CA  . THR D 3 203 ? 13.361  -12.415 14.42  1   55.48  ? 444 THR Q CA  1 
ATOM   6326  C  C   . THR D 3 203 ? 13.799  -12.522 15.879 1   55.16  ? 444 THR Q C   1 
ATOM   6327  O  O   . THR D 3 203 ? 12.976  -12.221 16.768 1   58.53  ? 444 THR Q O   1 
ATOM   6328  C  CB  . THR D 3 203 ? 13.429  -10.98  13.878 1   58.38  ? 444 THR Q CB  1 
ATOM   6329  O  OG1 . THR D 3 203 ? 13.29   -11.054 12.46  1   59.28  ? 444 THR Q OG1 1 
ATOM   6330  C  CG2 . THR D 3 203 ? 14.722  -10.257 14.196 1   59.42  ? 444 THR Q CG2 1 
ATOM   6331  N  N   . GLN D 3 204 ? 15.04   -12.948 16.1   1   52.89  ? 445 GLN Q N   1 
ATOM   6332  C  CA  . GLN D 3 204 ? 15.605  -13.234 17.438 1   51.35  ? 445 GLN Q CA  1 
ATOM   6333  C  C   . GLN D 3 204 ? 16.825  -12.338 17.627 1   49.96  ? 445 GLN Q C   1 
ATOM   6334  O  O   . GLN D 3 204 ? 17.627  -12.246 16.684 1   48.86  ? 445 GLN Q O   1 
ATOM   6335  C  CB  . GLN D 3 204 ? 15.969  -14.714 17.526 1   52.99  ? 445 GLN Q CB  1 
ATOM   6336  C  CG  . GLN D 3 204 ? 16.441  -15.157 18.903 1   55.23  ? 445 GLN Q CG  1 
ATOM   6337  C  CD  . GLN D 3 204 ? 16.927  -16.585 18.887 1   56.5   ? 445 GLN Q CD  1 
ATOM   6338  O  OE1 . GLN D 3 204 ? 16.595  -17.361 17.993 1   57.66  ? 445 GLN Q OE1 1 
ATOM   6339  N  NE2 . GLN D 3 204 ? 17.733  -16.938 19.878 1   55.73  ? 445 GLN Q NE2 1 
ATOM   6340  N  N   . LYS D 3 205 ? 16.929  -11.68  18.782 1   49.46  ? 446 LYS Q N   1 
ATOM   6341  C  CA  . LYS D 3 205 ? 18.156  -10.966 19.22  1   49.84  ? 446 LYS Q CA  1 
ATOM   6342  C  C   . LYS D 3 205 ? 18.573  -11.565 20.56  1   48.81  ? 446 LYS Q C   1 
ATOM   6343  O  O   . LYS D 3 205 ? 17.695  -11.733 21.432 1   45.26  ? 446 LYS Q O   1 
ATOM   6344  C  CB  . LYS D 3 205 ? 17.925  -9.455  19.294 1   50.6   ? 446 LYS Q CB  1 
ATOM   6345  C  CG  . LYS D 3 205 ? 17.7    -8.782  17.948 1   52.83  ? 446 LYS Q CG  1 
ATOM   6346  C  CD  . LYS D 3 205 ? 18.977  -8.512  17.19  1   55.57  ? 446 LYS Q CD  1 
ATOM   6347  C  CE  . LYS D 3 205 ? 18.737  -7.981  15.792 1   58.18  ? 446 LYS Q CE  1 
ATOM   6348  N  NZ  . LYS D 3 205 ? 19.641  -6.847  15.482 1   61.02  ? 446 LYS Q NZ  1 
ATOM   6349  N  N   . THR D 3 206 ? 19.854  -11.913 20.68  1   49.41  ? 447 THR Q N   1 
ATOM   6350  C  CA  . THR D 3 206 ? 20.443  -12.61  21.849 1   51.09  ? 447 THR Q CA  1 
ATOM   6351  C  C   . THR D 3 206 ? 21.543  -11.709 22.415 1   49.76  ? 447 THR Q C   1 
ATOM   6352  O  O   . THR D 3 206 ? 22.429  -11.317 21.639 1   52.59  ? 447 THR Q O   1 
ATOM   6353  C  CB  . THR D 3 206 ? 20.917  -14.016 21.454 1   50.81  ? 447 THR Q CB  1 
ATOM   6354  O  OG1 . THR D 3 206 ? 19.81   -14.69  20.851 1   51.2   ? 447 THR Q OG1 1 
ATOM   6355  C  CG2 . THR D 3 206 ? 21.425  -14.825 22.627 1   50.09  ? 447 THR Q CG2 1 
ATOM   6356  N  N   . ILE D 3 207 ? 21.448  -11.375 23.703 1   50.06  ? 448 ILE Q N   1 
ATOM   6357  C  CA  . ILE D 3 207 ? 22.419  -10.516 24.44  1   52.69  ? 448 ILE Q CA  1 
ATOM   6358  C  C   . ILE D 3 207 ? 23.01   -11.353 25.581 1   54.13  ? 448 ILE Q C   1 
ATOM   6359  O  O   . ILE D 3 207 ? 22.274  -12.178 26.164 1   54.45  ? 448 ILE Q O   1 
ATOM   6360  C  CB  . ILE D 3 207 ? 21.746  -9.208  24.927 1   54.1   ? 448 ILE Q CB  1 
ATOM   6361  C  CG1 . ILE D 3 207 ? 22.769  -8.104  25.202 1   56.61  ? 448 ILE Q CG1 1 
ATOM   6362  C  CG2 . ILE D 3 207 ? 20.851  -9.429  26.141 1   53.15  ? 448 ILE Q CG2 1 
ATOM   6363  C  CD1 . ILE D 3 207 ? 22.177  -6.732  25.297 0   54.59  ? 448 ILE Q CD1 1 
ATOM   6364  N  N   . ASP D 3 208 ? 24.303  -11.166 25.848 1   58.59  ? 449 ASP Q N   1 
ATOM   6365  C  CA  . ASP D 3 208 ? 24.998  -11.625 27.079 1   62.05  ? 449 ASP Q CA  1 
ATOM   6366  C  C   . ASP D 3 208 ? 25.872  -10.474 27.583 1   63.46  ? 449 ASP Q C   1 
ATOM   6367  O  O   . ASP D 3 208 ? 26.014  -9.466  26.856 1   66.02  ? 449 ASP Q O   1 
ATOM   6368  C  CB  . ASP D 3 208 ? 25.81   -12.905 26.839 1   64.82  ? 449 ASP Q CB  1 
ATOM   6369  C  CG  . ASP D 3 208 ? 26.814  -12.844 25.695 1   67.56  ? 449 ASP Q CG  1 
ATOM   6370  O  OD1 . ASP D 3 208 ? 27.233  -11.728 25.304 1   65.48  ? 449 ASP Q OD1 1 
ATOM   6371  O  OD2 . ASP D 3 208 ? 27.173  -13.924 25.204 1   71.68  ? 449 ASP Q OD2 1 
ATOM   6372  N  N   . ARG D 3 209 ? 26.442  -10.636 28.776 1   67.09  ? 450 ARG Q N   1 
ATOM   6373  C  CA  . ARG D 3 209 ? 27.381  -9.663  29.399 1   69.11  ? 450 ARG Q CA  1 
ATOM   6374  C  C   . ARG D 3 209 ? 28.696  -9.58   28.608 1   68.9   ? 450 ARG Q C   1 
ATOM   6375  O  O   . ARG D 3 209 ? 29.344  -8.532  28.699 1   70.49  ? 450 ARG Q O   1 
ATOM   6376  C  CB  . ARG D 3 209 ? 27.654  -10.045 30.855 1   71.09  ? 450 ARG Q CB  1 
ATOM   6377  C  CG  . ARG D 3 209 ? 28.212  -11.451 31.037 1   76.21  ? 450 ARG Q CG  1 
ATOM   6378  C  CD  . ARG D 3 209 ? 29.027  -11.612 32.3   1   78.57  ? 450 ARG Q CD  1 
ATOM   6379  N  NE  . ARG D 3 209 ? 30.144  -10.677 32.34  1   83.04  ? 450 ARG Q NE  1 
ATOM   6380  C  CZ  . ARG D 3 209 ? 30.885  -10.402 33.411 1   88.63  ? 450 ARG Q CZ  1 
ATOM   6381  N  NH1 . ARG D 3 209 ? 30.654  -10.996 34.574 1   92.22  ? 450 ARG Q NH1 1 
ATOM   6382  N  NH2 . ARG D 3 209 ? 31.867  -9.521  33.314 1   89.51  ? 450 ARG Q NH2 1 
ATOM   6383  N  N   . LEU D 3 210 ? 29.073  -10.634 27.872 1   72.48  ? 451 LEU Q N   1 
ATOM   6384  C  CA  . LEU D 3 210 ? 30.381  -10.75  27.163 1   76.94  ? 451 LEU Q CA  1 
ATOM   6385  C  C   . LEU D 3 210 ? 30.435  -9.84   25.923 1   80.04  ? 451 LEU Q C   1 
ATOM   6386  O  O   . LEU D 3 210 ? 31.557  -9.627  25.423 1   84.91  ? 451 LEU Q O   1 
ATOM   6387  C  CB  . LEU D 3 210 ? 30.631  -12.216 26.777 1   75.91  ? 451 LEU Q CB  1 
ATOM   6388  C  CG  . LEU D 3 210 ? 30.816  -13.19  27.941 1   73.79  ? 451 LEU Q CG  1 
ATOM   6389  C  CD1 . LEU D 3 210 ? 30.718  -14.633 27.464 0   76.18  ? 451 LEU Q CD1 1 
ATOM   6390  C  CD2 . LEU D 3 210 ? 32.12   -12.957 28.677 0   76.18  ? 451 LEU Q CD2 1 
ATOM   6391  N  N   . ALA D 3 211 ? 29.295  -9.346  25.421 1   82.96  ? 452 ALA Q N   1 
ATOM   6392  C  CA  . ALA D 3 211 ? 29.214  -8.396  24.282 1   84.16  ? 452 ALA Q CA  1 
ATOM   6393  C  C   . ALA D 3 211 ? 28.078  -7.394  24.518 1   83.42  ? 452 ALA Q C   1 
ATOM   6394  O  O   . ALA D 3 211 ? 28.309  -6.348  25.117 1   83.6   ? 452 ALA Q O   1 
ATOM   6395  C  CB  . ALA D 3 211 ? 29.023  -9.149  22.989 1   84.86  ? 452 ALA Q CB  1 
ATOM   6396  N  N   . GLU E 1 20  ? 5.572   -39.247 27.251 1   51.55  ? 2   GLU A N   1 
ATOM   6397  C  CA  . GLU E 1 20  ? 7.066   -39.344 27.116 1   49.63  ? 2   GLU A CA  1 
ATOM   6398  C  C   . GLU E 1 20  ? 7.498   -38.752 25.768 1   46.04  ? 2   GLU A C   1 
ATOM   6399  O  O   . GLU E 1 20  ? 6.828   -39.027 24.756 1   44.22  ? 2   GLU A O   1 
ATOM   6400  C  CB  . GLU E 1 20  ? 7.551   -40.793 27.26  1   49.98  ? 2   GLU A CB  1 
ATOM   6401  C  CG  . GLU E 1 20  ? 7.648   -41.272 28.703 1   50.28  ? 2   GLU A CG  1 
ATOM   6402  C  CD  . GLU E 1 20  ? 6.394   -41.894 29.304 1   50.57  ? 2   GLU A CD  1 
ATOM   6403  O  OE1 . GLU E 1 20  ? 6.542   -42.751 30.197 1   52.56  ? 2   GLU A OE1 1 
ATOM   6404  O  OE2 . GLU E 1 20  ? 5.275   -41.523 28.889 1   47.6   ? 2   GLU A OE2 1 
ATOM   6405  N  N   . VAL E 1 21  ? 8.578   -37.968 25.771 1   44.46  ? 3   VAL A N   1 
ATOM   6406  C  CA  . VAL E 1 21  ? 9.201   -37.384 24.546 1   44.95  ? 3   VAL A CA  1 
ATOM   6407  C  C   . VAL E 1 21  ? 9.723   -38.54  23.688 1   44.55  ? 3   VAL A C   1 
ATOM   6408  O  O   . VAL E 1 21  ? 10.355  -39.441 24.248 1   44.74  ? 3   VAL A O   1 
ATOM   6409  C  CB  . VAL E 1 21  ? 10.326  -36.391 24.899 1   44.73  ? 3   VAL A CB  1 
ATOM   6410  C  CG1 . VAL E 1 21  ? 11.08   -35.915 23.666 1   44.35  ? 3   VAL A CG1 1 
ATOM   6411  C  CG2 . VAL E 1 21  ? 9.799   -35.199 25.689 1   45.94  ? 3   VAL A CG2 1 
ATOM   6412  N  N   . GLN E 1 22  ? 9.45    -38.513 22.383 1   46.78  ? 4   GLN A N   1 
ATOM   6413  C  CA  . GLN E 1 22  ? 9.961   -39.514 21.411 1   49.64  ? 4   GLN A CA  1 
ATOM   6414  C  C   . GLN E 1 22  ? 10.333  -38.811 20.1   1   46.28  ? 4   GLN A C   1 
ATOM   6415  O  O   . GLN E 1 22  ? 9.583   -37.913 19.667 1   45.62  ? 4   GLN A O   1 
ATOM   6416  C  CB  . GLN E 1 22  ? 8.924   -40.611 21.179 1   56.04  ? 4   GLN A CB  1 
ATOM   6417  C  CG  . GLN E 1 22  ? 9.525   -41.89  20.615 1   63.78  ? 4   GLN A CG  1 
ATOM   6418  C  CD  . GLN E 1 22  ? 8.474   -42.893 20.204 1   71.15  ? 4   GLN A CD  1 
ATOM   6419  O  OE1 . GLN E 1 22  ? 8.418   -43.315 19.048 1   76.97  ? 4   GLN A OE1 1 
ATOM   6420  N  NE2 . GLN E 1 22  ? 7.631   -43.285 21.148 1   71.41  ? 4   GLN A NE2 1 
ATOM   6421  N  N   . LEU E 1 23  ? 11.462  -39.212 19.512 1   42.97  ? 5   LEU A N   1 
ATOM   6422  C  CA  . LEU E 1 23  ? 11.972  -38.728 18.205 1   41.77  ? 5   LEU A CA  1 
ATOM   6423  C  C   . LEU E 1 23  ? 12.288  -39.953 17.342 1   42.8   ? 5   LEU A C   1 
ATOM   6424  O  O   . LEU E 1 23  ? 13.109  -40.776 17.796 1   42.37  ? 5   LEU A O   1 
ATOM   6425  C  CB  . LEU E 1 23  ? 13.23   -37.885 18.446 1   42.19  ? 5   LEU A CB  1 
ATOM   6426  C  CG  . LEU E 1 23  ? 13.07   -36.638 19.317 1   41.76  ? 5   LEU A CG  1 
ATOM   6427  C  CD1 . LEU E 1 23  ? 14.425  -36.082 19.72  1   41.97  ? 5   LEU A CD1 1 
ATOM   6428  C  CD2 . LEU E 1 23  ? 12.271  -35.566 18.602 1   42.53  ? 5   LEU A CD2 1 
ATOM   6429  N  N   . LEU E 1 24  ? 11.643  -40.093 16.176 1   44.59  ? 6   LEU A N   1 
ATOM   6430  C  CA  . LEU E 1 24  ? 11.933  -41.168 15.185 1   47.12  ? 6   LEU A CA  1 
ATOM   6431  C  C   . LEU E 1 24  ? 12.513  -40.552 13.91  1   44.13  ? 6   LEU A C   1 
ATOM   6432  O  O   . LEU E 1 24  ? 11.747  -39.939 13.151 1   43.25  ? 6   LEU A O   1 
ATOM   6433  C  CB  . LEU E 1 24  ? 10.659  -41.958 14.866 1   51.87  ? 6   LEU A CB  1 
ATOM   6434  C  CG  . LEU E 1 24  ? 10.061  -42.797 15.996 1   57.35  ? 6   LEU A CG  1 
ATOM   6435  C  CD1 . LEU E 1 24  ? 8.958   -43.69  15.444 1   59.99  ? 6   LEU A CD1 1 
ATOM   6436  C  CD2 . LEU E 1 24  ? 11.108  -43.644 16.715 1   59.33  ? 6   LEU A CD2 1 
ATOM   6437  N  N   . GLU E 1 25  ? 13.817  -40.736 13.689 1   44.59  ? 7   GLU A N   1 
ATOM   6438  C  CA  . GLU E 1 25  ? 14.514  -40.374 12.427 1   44.23  ? 7   GLU A CA  1 
ATOM   6439  C  C   . GLU E 1 25  ? 14.141  -41.383 11.342 1   44.96  ? 7   GLU A C   1 
ATOM   6440  O  O   . GLU E 1 25  ? 14.062  -42.582 11.653 1   48.3   ? 7   GLU A O   1 
ATOM   6441  C  CB  . GLU E 1 25  ? 16.038  -40.393 12.572 1   44.25  ? 7   GLU A CB  1 
ATOM   6442  C  CG  . GLU E 1 25  ? 16.588  -39.374 13.553 1   43.96  ? 7   GLU A CG  1 
ATOM   6443  C  CD  . GLU E 1 25  ? 16.741  -39.873 14.978 1   43.75  ? 7   GLU A CD  1 
ATOM   6444  O  OE1 . GLU E 1 25  ? 16.073  -40.861 15.33  1   44.3   ? 7   GLU A OE1 1 
ATOM   6445  O  OE2 . GLU E 1 25  ? 17.539  -39.284 15.728 1   43.94  ? 7   GLU A OE2 1 
ATOM   6446  N  N   . SER E 1 26  ? 13.946  -40.909 10.113 1   48.14  ? 8   SER A N   1 
ATOM   6447  C  CA  . SER E 1 26  ? 13.828  -41.738 8.884  1   50.31  ? 8   SER A CA  1 
ATOM   6448  C  C   . SER E 1 26  ? 14.456  -40.988 7.705  1   49.85  ? 8   SER A C   1 
ATOM   6449  O  O   . SER E 1 26  ? 14.702  -39.777 7.844  1   48.79  ? 8   SER A O   1 
ATOM   6450  C  CB  . SER E 1 26  ? 12.39   -42.105 8.608  1   51.31  ? 8   SER A CB  1 
ATOM   6451  O  OG  . SER E 1 26  ? 11.583  -40.942 8.498  1   53.41  ? 8   SER A OG  1 
ATOM   6452  N  N   . GLY E 1 27  ? 14.709  -41.698 6.601  1   50.63  ? 9   GLY A N   1 
ATOM   6453  C  CA  . GLY E 1 27  ? 15.226  -41.136 5.338  1   49.6   ? 9   GLY A CA  1 
ATOM   6454  C  C   . GLY E 1 27  ? 16.592  -41.688 4.975  1   51.27  ? 9   GLY A C   1 
ATOM   6455  O  O   . GLY E 1 27  ? 16.957  -41.58  3.793  1   54.67  ? 9   GLY A O   1 
ATOM   6456  N  N   . GLY E 1 28  ? 17.329  -42.248 5.944  1   50.83  ? 10  GLY A N   1 
ATOM   6457  C  CA  . GLY E 1 28  ? 18.701  -42.756 5.748  1   50.18  ? 10  GLY A CA  1 
ATOM   6458  C  C   . GLY E 1 28  ? 18.768  -43.854 4.701  1   51.26  ? 10  GLY A C   1 
ATOM   6459  O  O   . GLY E 1 28  ? 17.747  -44.54  4.479  1   58.53  ? 10  GLY A O   1 
ATOM   6460  N  N   . GLY E 1 29  ? 19.938  -44.021 4.084  1   49.52  ? 11  GLY A N   1 
ATOM   6461  C  CA  . GLY E 1 29  ? 20.197  -45.04  3.052  1   49.13  ? 11  GLY A CA  1 
ATOM   6462  C  C   . GLY E 1 29  ? 21.362  -44.65  2.163  1   49.47  ? 11  GLY A C   1 
ATOM   6463  O  O   . GLY E 1 29  ? 22.144  -43.768 2.567  1   50.49  ? 11  GLY A O   1 
ATOM   6464  N  N   . LEU E 1 30  ? 21.475  -45.29  0.998  1   50.41  ? 12  LEU A N   1 
ATOM   6465  C  CA  . LEU E 1 30  ? 22.574  -45.058 0.029  1   51.54  ? 12  LEU A CA  1 
ATOM   6466  C  C   . LEU E 1 30  ? 22.259  -43.806 -0.796 1   51.87  ? 12  LEU A C   1 
ATOM   6467  O  O   . LEU E 1 30  ? 21.096  -43.635 -1.204 1   52.63  ? 12  LEU A O   1 
ATOM   6468  C  CB  . LEU E 1 30  ? 22.744  -46.28  -0.876 1   52.96  ? 12  LEU A CB  1 
ATOM   6469  C  CG  . LEU E 1 30  ? 23.797  -46.133 -1.975 1   55.26  ? 12  LEU A CG  1 
ATOM   6470  C  CD1 . LEU E 1 30  ? 25.193  -45.972 -1.39  1   54.21  ? 12  LEU A CD1 1 
ATOM   6471  C  CD2 . LEU E 1 30  ? 23.75   -47.319 -2.922 1   59.37  ? 12  LEU A CD2 1 
ATOM   6472  N  N   . VAL E 1 31  ? 23.276  -42.98  -1.035 1   51.74  ? 13  VAL A N   1 
ATOM   6473  C  CA  . VAL E 1 31  ? 23.234  -41.809 -1.959 1   54.03  ? 13  VAL A CA  1 
ATOM   6474  C  C   . VAL E 1 31  ? 24.598  -41.717 -2.645 1   55.01  ? 13  VAL A C   1 
ATOM   6475  O  O   . VAL E 1 31  ? 25.608  -41.942 -1.953 1   56.37  ? 13  VAL A O   1 
ATOM   6476  C  CB  . VAL E 1 31  ? 22.871  -40.512 -1.208 1   55.22  ? 13  VAL A CB  1 
ATOM   6477  C  CG1 . VAL E 1 31  ? 21.404  -40.496 -0.813 1   56.39  ? 13  VAL A CG1 1 
ATOM   6478  C  CG2 . VAL E 1 31  ? 23.745  -40.277 0.015  1   54.34  ? 13  VAL A CG2 1 
ATOM   6479  N  N   . GLN E 1 32  ? 24.629  -41.427 -3.949 1   57.98  ? 14  GLN A N   1 
ATOM   6480  C  CA  . GLN E 1 32  ? 25.896  -41.336 -4.732 1   60.02  ? 14  GLN A CA  1 
ATOM   6481  C  C   . GLN E 1 32  ? 26.568  -40.003 -4.391 1   55.41  ? 14  GLN A C   1 
ATOM   6482  O  O   . GLN E 1 32  ? 25.871  -39.033 -4.081 1   50.23  ? 14  GLN A O   1 
ATOM   6483  C  CB  . GLN E 1 32  ? 25.637  -41.496 -6.235 1   66.79  ? 14  GLN A CB  1 
ATOM   6484  C  CG  . GLN E 1 32  ? 24.846  -42.749 -6.619 1   72.32  ? 14  GLN A CG  1 
ATOM   6485  C  CD  . GLN E 1 32  ? 25.521  -44.05  -6.243 1   76.99  ? 14  GLN A CD  1 
ATOM   6486  O  OE1 . GLN E 1 32  ? 26.499  -44.463 -6.863 1   79.5   ? 14  GLN A OE1 1 
ATOM   6487  N  NE2 . GLN E 1 32  ? 24.994  -44.728 -5.232 1   77.93  ? 14  GLN A NE2 1 
ATOM   6488  N  N   . PRO E 1 33  ? 27.924  -39.916 -4.383 1   52.88  ? 15  PRO A N   1 
ATOM   6489  C  CA  . PRO E 1 33  ? 28.62   -38.641 -4.19  1   53.92  ? 15  PRO A CA  1 
ATOM   6490  C  C   . PRO E 1 33  ? 28.097  -37.55  -5.137 1   53.26  ? 15  PRO A C   1 
ATOM   6491  O  O   . PRO E 1 33  ? 27.92   -37.838 -6.307 1   56.12  ? 15  PRO A O   1 
ATOM   6492  C  CB  . PRO E 1 33  ? 30.091  -38.967 -4.491 1   54.32  ? 15  PRO A CB  1 
ATOM   6493  C  CG  . PRO E 1 33  ? 30.214  -40.434 -4.15  1   53.43  ? 15  PRO A CG  1 
ATOM   6494  C  CD  . PRO E 1 33  ? 28.869  -41.035 -4.507 1   53.69  ? 15  PRO A CD  1 
ATOM   6495  N  N   . GLY E 1 34  ? 27.819  -36.359 -4.597 1   50.04  ? 16  GLY A N   1 
ATOM   6496  C  CA  . GLY E 1 34  ? 27.152  -35.253 -5.308 1   49.14  ? 16  GLY A CA  1 
ATOM   6497  C  C   . GLY E 1 34  ? 25.639  -35.333 -5.198 1   49.36  ? 16  GLY A C   1 
ATOM   6498  O  O   . GLY E 1 34  ? 24.969  -34.341 -5.557 1   47.41  ? 16  GLY A O   1 
ATOM   6499  N  N   . GLY E 1 35  ? 25.104  -36.454 -4.704 1   51.27  ? 17  GLY A N   1 
ATOM   6500  C  CA  . GLY E 1 35  ? 23.652  -36.686 -4.591 1   52.96  ? 17  GLY A CA  1 
ATOM   6501  C  C   . GLY E 1 35  ? 23.042  -35.89  -3.454 1   52.26  ? 17  GLY A C   1 
ATOM   6502  O  O   . GLY E 1 35  ? 23.797  -35.247 -2.696 1   53.94  ? 17  GLY A O   1 
ATOM   6503  N  N   . SER E 1 36  ? 21.717  -35.919 -3.343 1   52.16  ? 18  SER A N   1 
ATOM   6504  C  CA  . SER E 1 36  ? 20.959  -35.269 -2.249 1   53.86  ? 18  SER A CA  1 
ATOM   6505  C  C   . SER E 1 36  ? 20.076  -36.305 -1.544 1   55.21  ? 18  SER A C   1 
ATOM   6506  O  O   . SER E 1 36  ? 19.654  -37.284 -2.185 1   57.3   ? 18  SER A O   1 
ATOM   6507  C  CB  . SER E 1 36  ? 20.17   -34.081 -2.746 1   55.34  ? 18  SER A CB  1 
ATOM   6508  O  OG  . SER E 1 36  ? 19.369  -34.421 -3.863 1   59.72  ? 18  SER A OG  1 
ATOM   6509  N  N   . LEU E 1 37  ? 19.854  -36.096 -0.247 1   56.19  ? 19  LEU A N   1 
ATOM   6510  C  CA  . LEU E 1 37  ? 18.985  -36.925 0.62   1   54.37  ? 19  LEU A CA  1 
ATOM   6511  C  C   . LEU E 1 37  ? 18.174  -35.994 1.515  1   52.97  ? 19  LEU A C   1 
ATOM   6512  O  O   . LEU E 1 37  ? 18.668  -34.89  1.808  1   54.44  ? 19  LEU A O   1 
ATOM   6513  C  CB  . LEU E 1 37  ? 19.868  -37.846 1.466  1   56.87  ? 19  LEU A CB  1 
ATOM   6514  C  CG  . LEU E 1 37  ? 19.145  -38.948 2.238  1   57.37  ? 19  LEU A CG  1 
ATOM   6515  C  CD1 . LEU E 1 37  ? 18.344  -39.842 1.305  1   59.03  ? 19  LEU A CD1 1 
ATOM   6516  C  CD2 . LEU E 1 37  ? 20.138  -39.778 3.034  1   57.27  ? 19  LEU A CD2 1 
ATOM   6517  N  N   . ARG E 1 38  ? 16.99   -36.435 1.934  1   51.38  ? 20  ARG A N   1 
ATOM   6518  C  CA  . ARG E 1 38  ? 16.153  -35.738 2.94   1   51.43  ? 20  ARG A CA  1 
ATOM   6519  C  C   . ARG E 1 38  ? 15.929  -36.685 4.123  1   50.03  ? 20  ARG A C   1 
ATOM   6520  O  O   . ARG E 1 38  ? 15.371  -37.78  3.904  1   52.61  ? 20  ARG A O   1 
ATOM   6521  C  CB  . ARG E 1 38  ? 14.832  -35.294 2.31   1   54.16  ? 20  ARG A CB  1 
ATOM   6522  C  CG  . ARG E 1 38  ? 14.123  -34.193 3.084  1   56.72  ? 20  ARG A CG  1 
ATOM   6523  C  CD  . ARG E 1 38  ? 12.625  -34.229 2.868  1   60.29  ? 20  ARG A CD  1 
ATOM   6524  N  NE  . ARG E 1 38  ? 11.993  -32.952 3.167  1   64.1   ? 20  ARG A NE  1 
ATOM   6525  C  CZ  . ARG E 1 38  ? 10.68   -32.723 3.163  1   67.85  ? 20  ARG A CZ  1 
ATOM   6526  N  NH1 . ARG E 1 38  ? 9.82    -33.697 2.891  1   67.17  ? 20  ARG A NH1 1 
ATOM   6527  N  NH2 . ARG E 1 38  ? 10.232  -31.511 3.451  1   70.38  ? 20  ARG A NH2 1 
ATOM   6528  N  N   . LEU E 1 39  ? 16.371  -36.285 5.319  1   47.8   ? 21  LEU A N   1 
ATOM   6529  C  CA  . LEU E 1 39  ? 16.038  -36.963 6.6    1   45.09  ? 21  LEU A CA  1 
ATOM   6530  C  C   . LEU E 1 39  ? 14.814  -36.273 7.205  1   43.05  ? 21  LEU A C   1 
ATOM   6531  O  O   . LEU E 1 39  ? 14.754  -35.038 7.154  1   39.06  ? 21  LEU A O   1 
ATOM   6532  C  CB  . LEU E 1 39  ? 17.237  -36.912 7.553  1   43.73  ? 21  LEU A CB  1 
ATOM   6533  C  CG  . LEU E 1 39  ? 18.562  -37.407 6.977  1   44.49  ? 21  LEU A CG  1 
ATOM   6534  C  CD1 . LEU E 1 39  ? 19.65   -37.371 8.038  1   45.17  ? 21  LEU A CD1 1 
ATOM   6535  C  CD2 . LEU E 1 39  ? 18.437  -38.81  6.397  1   43.59  ? 21  LEU A CD2 1 
ATOM   6536  N  N   . SER E 1 40  ? 13.86   -37.065 7.697  1   44.79  ? 22  SER A N   1 
ATOM   6537  C  CA  . SER E 1 40  ? 12.696  -36.629 8.509  1   45.24  ? 22  SER A CA  1 
ATOM   6538  C  C   . SER E 1 40  ? 12.944  -37.037 9.961  1   44.46  ? 22  SER A C   1 
ATOM   6539  O  O   . SER E 1 40  ? 13.761  -37.94  10.183 1   45.37  ? 22  SER A O   1 
ATOM   6540  C  CB  . SER E 1 40  ? 11.417  -37.224 7.99   1   48.05  ? 22  SER A CB  1 
ATOM   6541  O  OG  . SER E 1 40  ? 11.337  -37.092 6.578  1   52.1   ? 22  SER A OG  1 
ATOM   6542  N  N   . CYS E 1 41  ? 12.281  -36.375 10.904 1   44.96  ? 23  CYS A N   1 
ATOM   6543  C  CA  . CYS E 1 41  ? 12.337  -36.686 12.354 1   45.62  ? 23  CYS A CA  1 
ATOM   6544  C  C   . CYS E 1 41  ? 10.983  -36.355 12.981 1   44.03  ? 23  CYS A C   1 
ATOM   6545  O  O   . CYS E 1 41  ? 10.75   -35.172 13.248 1   42.3   ? 23  CYS A O   1 
ATOM   6546  C  CB  . CYS E 1 41  ? 13.455  -35.917 13.047 1   48.6   ? 23  CYS A CB  1 
ATOM   6547  S  SG  . CYS E 1 41  ? 13.331  -35.94  14.856 1   54.77  ? 23  CYS A SG  1 
ATOM   6548  N  N   . ALA E 1 42  ? 10.146  -37.372 13.205 1   43.96  ? 24  ALA A N   1 
ATOM   6549  C  CA  . ALA E 1 42  ? 8.792   -37.24  13.793 1   43.04  ? 24  ALA A CA  1 
ATOM   6550  C  C   . ALA E 1 42  ? 8.899   -37.096 15.316 1   42.73  ? 24  ALA A C   1 
ATOM   6551  O  O   . ALA E 1 42  ? 9.458   -38     15.959 1   41.86  ? 24  ALA A O   1 
ATOM   6552  C  CB  . ALA E 1 42  ? 7.938   -38.424 13.408 1   43.3   ? 24  ALA A CB  1 
ATOM   6553  N  N   . ALA E 1 43  ? 8.37    -35.996 15.858 1   43.73  ? 25  ALA A N   1 
ATOM   6554  C  CA  . ALA E 1 43  ? 8.305   -35.694 17.307 1   43.76  ? 25  ALA A CA  1 
ATOM   6555  C  C   . ALA E 1 43  ? 6.972   -36.198 17.874 1   43.53  ? 25  ALA A C   1 
ATOM   6556  O  O   . ALA E 1 43  ? 5.956   -36.101 17.162 1   45.32  ? 25  ALA A O   1 
ATOM   6557  C  CB  . ALA E 1 43  ? 8.474   -34.209 17.528 1   43.29  ? 25  ALA A CB  1 
ATOM   6558  N  N   . SER E 1 44  ? 6.984   -36.713 19.105 1   42.94  ? 26  SER A N   1 
ATOM   6559  C  CA  . SER E 1 44  ? 5.783   -37.162 19.86  1   46.28  ? 26  SER A CA  1 
ATOM   6560  C  C   . SER E 1 44  ? 5.934   -36.764 21.33  1   46.89  ? 26  SER A C   1 
ATOM   6561  O  O   . SER E 1 44  ? 7.083   -36.77  21.823 1   46.02  ? 26  SER A O   1 
ATOM   6562  C  CB  . SER E 1 44  ? 5.56    -38.655 19.744 1   47.51  ? 26  SER A CB  1 
ATOM   6563  O  OG  . SER E 1 44  ? 5.587   -39.077 18.391 1   49.91  ? 26  SER A OG  1 
ATOM   6564  N  N   . GLY E 1 45  ? 4.816   -36.443 21.991 1   46.6   ? 27  GLY A N   1 
ATOM   6565  C  CA  . GLY E 1 45  ? 4.761   -36.117 23.43  1   47.83  ? 27  GLY A CA  1 
ATOM   6566  C  C   . GLY E 1 45  ? 5.383   -34.768 23.75  1   48.19  ? 27  GLY A C   1 
ATOM   6567  O  O   . GLY E 1 45  ? 5.641   -34.519 24.939 1   53.87  ? 27  GLY A O   1 
ATOM   6568  N  N   . PHE E 1 46  ? 5.628   -33.935 22.733 1   46.34  ? 28  PHE A N   1 
ATOM   6569  C  CA  . PHE E 1 46  ? 6.061   -32.516 22.843 1   45.49  ? 28  PHE A CA  1 
ATOM   6570  C  C   . PHE E 1 46  ? 5.849   -31.862 21.473 1   45.52  ? 28  PHE A C   1 
ATOM   6571  O  O   . PHE E 1 46  ? 5.732   -32.603 20.467 1   43.48  ? 28  PHE A O   1 
ATOM   6572  C  CB  . PHE E 1 46  ? 7.511   -32.41  23.332 1   44.84  ? 28  PHE A CB  1 
ATOM   6573  C  CG  . PHE E 1 46  ? 8.565   -32.537 22.258 1   46.94  ? 28  PHE A CG  1 
ATOM   6574  C  CD1 . PHE E 1 46  ? 8.853   -33.765 21.675 1   45.93  ? 28  PHE A CD1 1 
ATOM   6575  C  CD2 . PHE E 1 46  ? 9.27    -31.424 21.822 1   46.74  ? 28  PHE A CD2 1 
ATOM   6576  C  CE1 . PHE E 1 46  ? 9.824   -33.877 20.689 1   44.18  ? 28  PHE A CE1 1 
ATOM   6577  C  CE2 . PHE E 1 46  ? 10.239  -31.538 20.835 1   45.52  ? 28  PHE A CE2 1 
ATOM   6578  C  CZ  . PHE E 1 46  ? 10.512  -32.761 20.268 1   44.47  ? 28  PHE A CZ  1 
ATOM   6579  N  N   . THR E 1 47  ? 5.789   -30.53  21.436 1   47.14  ? 29  THR A N   1 
ATOM   6580  C  CA  . THR E 1 47  ? 5.629   -29.723 20.197 1   48.49  ? 29  THR A CA  1 
ATOM   6581  C  C   . THR E 1 47  ? 7.004   -29.192 19.784 1   49.24  ? 29  THR A C   1 
ATOM   6582  O  O   . THR E 1 47  ? 7.522   -28.317 20.493 1   50.06  ? 29  THR A O   1 
ATOM   6583  C  CB  . THR E 1 47  ? 4.595   -28.61  20.402 1   49.85  ? 29  THR A CB  1 
ATOM   6584  O  OG1 . THR E 1 47  ? 3.445   -29.198 21.014 1   48.3   ? 29  THR A OG1 1 
ATOM   6585  C  CG2 . THR E 1 47  ? 4.21    -27.925 19.109 1   50.06  ? 29  THR A CG2 1 
ATOM   6586  N  N   . SER E 1 48  ? 7.558   -29.695 18.675 1   52.36  ? 30  SER A N   1 
ATOM   6587  C  CA  . SER E 1 48  ? 8.93    -29.387 18.184 1   52.86  ? 30  SER A CA  1 
ATOM   6588  C  C   . SER E 1 48  ? 9.101   -27.889 17.879 1   52.75  ? 30  SER A C   1 
ATOM   6589  O  O   . SER E 1 48  ? 10.259  -27.431 17.869 1   55.41  ? 30  SER A O   1 
ATOM   6590  C  CB  . SER E 1 48  ? 9.288   -30.234 16.99  1   52.05  ? 30  SER A CB  1 
ATOM   6591  O  OG  . SER E 1 48  ? 8.464   -29.916 15.883 1   56.31  ? 30  SER A OG  1 
ATOM   6592  N  N   . SER E 1 49  ? 8.011   -27.155 17.632 1   52.68  ? 31  SER A N   1 
ATOM   6593  C  CA  . SER E 1 49  ? 8.018   -25.685 17.394 1   53.54  ? 31  SER A CA  1 
ATOM   6594  C  C   . SER E 1 49  ? 8.476   -24.94  18.653 1   53.62  ? 31  SER A C   1 
ATOM   6595  O  O   . SER E 1 49  ? 9.207   -23.945 18.507 1   56.85  ? 31  SER A O   1 
ATOM   6596  C  CB  . SER E 1 49  ? 6.666   -25.194 16.938 1   54.76  ? 31  SER A CB  1 
ATOM   6597  O  OG  . SER E 1 49  ? 5.737   -25.185 18.011 1   56.6   ? 31  SER A OG  1 
ATOM   6598  N  N   . ASN E 1 50  ? 8.087   -25.423 19.839 1   52.37  ? 32  ASN A N   1 
ATOM   6599  C  CA  . ASN E 1 50  ? 8.238   -24.709 21.139 1   51.37  ? 32  ASN A CA  1 
ATOM   6600  C  C   . ASN E 1 50  ? 9.649   -24.878 21.737 1   50.46  ? 32  ASN A C   1 
ATOM   6601  O  O   . ASN E 1 50  ? 9.825   -24.476 22.913 1   52.93  ? 32  ASN A O   1 
ATOM   6602  C  CB  . ASN E 1 50  ? 7.201   -25.191 22.162 1   51.3   ? 32  ASN A CB  1 
ATOM   6603  C  CG  . ASN E 1 50  ? 5.765   -25.01  21.717 1   50.84  ? 32  ASN A CG  1 
ATOM   6604  O  OD1 . ASN E 1 50  ? 5.498   -24.666 20.566 1   51.01  ? 32  ASN A OD1 1 
ATOM   6605  N  ND2 . ASN E 1 50  ? 4.834   -25.244 22.628 1   50.39  ? 32  ASN A ND2 1 
ATOM   6606  N  N   . TYR E 1 51  ? 10.613  -25.453 21.003 1   47.52  ? 33  TYR A N   1 
ATOM   6607  C  CA  . TYR E 1 51  ? 11.977  -25.767 21.51  1   46.6   ? 33  TYR A CA  1 
ATOM   6608  C  C   . TYR E 1 51  ? 13.034  -25.515 20.429 1   44.87  ? 33  TYR A C   1 
ATOM   6609  O  O   . TYR E 1 51  ? 12.716  -25.497 19.22  1   44.01  ? 33  TYR A O   1 
ATOM   6610  C  CB  . TYR E 1 51  ? 12.055  -27.216 22.004 1   47.48  ? 33  TYR A CB  1 
ATOM   6611  C  CG  . TYR E 1 51  ? 11.081  -27.529 23.11  1   50.58  ? 33  TYR A CG  1 
ATOM   6612  C  CD1 . TYR E 1 51  ? 11.399  -27.297 24.439 1   51.77  ? 33  TYR A CD1 1 
ATOM   6613  C  CD2 . TYR E 1 51  ? 9.811   -28.003 22.822 1   52.71  ? 33  TYR A CD2 1 
ATOM   6614  C  CE1 . TYR E 1 51  ? 10.489  -27.553 25.454 1   52.71  ? 33  TYR A CE1 1 
ATOM   6615  C  CE2 . TYR E 1 51  ? 8.885   -28.256 23.822 1   52.79  ? 33  TYR A CE2 1 
ATOM   6616  C  CZ  . TYR E 1 51  ? 9.227   -28.033 25.145 1   52.7   ? 33  TYR A CZ  1 
ATOM   6617  O  OH  . TYR E 1 51  ? 8.325   -28.29  26.136 1   54.27  ? 33  TYR A OH  1 
ATOM   6618  N  N   . LEU E 1 52  ? 14.274  -25.323 20.882 1   42.49  ? 34  LEU A N   1 
ATOM   6619  C  CA  . LEU E 1 52  ? 15.492  -25.411 20.042 1   42.59  ? 34  LEU A CA  1 
ATOM   6620  C  C   . LEU E 1 52  ? 15.682  -26.887 19.661 1   43.07  ? 34  LEU A C   1 
ATOM   6621  O  O   . LEU E 1 52  ? 15.798  -27.732 20.575 1   42.66  ? 34  LEU A O   1 
ATOM   6622  C  CB  . LEU E 1 52  ? 16.674  -24.834 20.831 1   43.87  ? 34  LEU A CB  1 
ATOM   6623  C  CG  . LEU E 1 52  ? 18.037  -24.848 20.14  1   46.25  ? 34  LEU A CG  1 
ATOM   6624  C  CD1 . LEU E 1 52  ? 18.014  -24.065 18.844 1   47.54  ? 34  LEU A CD1 1 
ATOM   6625  C  CD2 . LEU E 1 52  ? 19.106  -24.276 21.053 1   47.28  ? 34  LEU A CD2 1 
ATOM   6626  N  N   . MET E 1 53  ? 15.619  -27.187 18.361 1   42.73  ? 35  MET A N   1 
ATOM   6627  C  CA  . MET E 1 53  ? 15.73   -28.551 17.783 1   41.74  ? 35  MET A CA  1 
ATOM   6628  C  C   . MET E 1 53  ? 17.007  -28.608 16.943 1   42.31  ? 35  MET A C   1 
ATOM   6629  O  O   . MET E 1 53  ? 17.302  -27.607 16.266 1   43     ? 35  MET A O   1 
ATOM   6630  C  CB  . MET E 1 53  ? 14.531  -28.873 16.885 1   41.94  ? 35  MET A CB  1 
ATOM   6631  C  CG  . MET E 1 53  ? 13.194  -28.924 17.611 1   42.06  ? 35  MET A CG  1 
ATOM   6632  S  SD  . MET E 1 53  ? 13.07   -30.212 18.878 1   41.43  ? 35  MET A SD  1 
ATOM   6633  C  CE  . MET E 1 53  ? 13.327  -31.704 17.915 1   40.43  ? 35  MET A CE  1 
ATOM   6634  N  N   . SER E 1 54  ? 17.719  -29.736 16.979 1   40.99  ? 36  SER A N   1 
ATOM   6635  C  CA  . SER E 1 54  ? 19.053  -29.901 16.35  1   41.16  ? 36  SER A CA  1 
ATOM   6636  C  C   . SER E 1 54  ? 19.155  -31.247 15.625 1   39.73  ? 36  SER A C   1 
ATOM   6637  O  O   . SER E 1 54  ? 18.441  -32.19  16.011 1   36.69  ? 36  SER A O   1 
ATOM   6638  C  CB  . SER E 1 54  ? 20.157  -29.771 17.368 1   42.7   ? 36  SER A CB  1 
ATOM   6639  O  OG  . SER E 1 54  ? 20.002  -28.596 18.149 1   45.82  ? 36  SER A OG  1 
ATOM   6640  N  N   . TRP E 1 55  ? 20.022  -31.297 14.609 1   37.67  ? 37  TRP A N   1 
ATOM   6641  C  CA  . TRP E 1 55  ? 20.6    -32.53  14.023 1   37.61  ? 37  TRP A CA  1 
ATOM   6642  C  C   . TRP E 1 55  ? 22.042  -32.664 14.52  1   37.9   ? 37  TRP A C   1 
ATOM   6643  O  O   . TRP E 1 55  ? 22.746  -31.652 14.531 1   38.72  ? 37  TRP A O   1 
ATOM   6644  C  CB  . TRP E 1 55  ? 20.502  -32.497 12.491 1   37.93  ? 37  TRP A CB  1 
ATOM   6645  C  CG  . TRP E 1 55  ? 19.104  -32.705 11.996 1   36.86  ? 37  TRP A CG  1 
ATOM   6646  C  CD1 . TRP E 1 55  ? 18.177  -31.743 11.733 1   36.9   ? 37  TRP A CD1 1 
ATOM   6647  C  CD2 . TRP E 1 55  ? 18.446  -33.965 11.77  1   37.21  ? 37  TRP A CD2 1 
ATOM   6648  N  NE1 . TRP E 1 55  ? 16.999  -32.31  11.331 1   37.19  ? 37  TRP A NE1 1 
ATOM   6649  C  CE2 . TRP E 1 55  ? 17.131  -33.672 11.347 1   36.85  ? 37  TRP A CE2 1 
ATOM   6650  C  CE3 . TRP E 1 55  ? 18.836  -35.306 11.88  1   36.25  ? 37  TRP A CE3 1 
ATOM   6651  C  CZ2 . TRP E 1 55  ? 16.214  -34.671 11.023 1   35.42  ? 37  TRP A CZ2 1 
ATOM   6652  C  CZ3 . TRP E 1 55  ? 17.931  -36.292 11.559 1   35.56  ? 37  TRP A CZ3 1 
ATOM   6653  C  CH2 . TRP E 1 55  ? 16.637  -35.976 11.14  1   35.99  ? 37  TRP A CH2 1 
ATOM   6654  N  N   . VAL E 1 56  ? 22.438  -33.86  14.959 1   39.51  ? 38  VAL A N   1 
ATOM   6655  C  CA  . VAL E 1 56  ? 23.821  -34.195 15.42  1   39.51  ? 38  VAL A CA  1 
ATOM   6656  C  C   . VAL E 1 56  ? 24.214  -35.505 14.739 1   40.57  ? 38  VAL A C   1 
ATOM   6657  O  O   . VAL E 1 56  ? 23.381  -36.425 14.739 1   46.04  ? 38  VAL A O   1 
ATOM   6658  C  CB  . VAL E 1 56  ? 23.901  -34.314 16.955 1   39.06  ? 38  VAL A CB  1 
ATOM   6659  C  CG1 . VAL E 1 56  ? 25.309  -34.651 17.43  1   38.2   ? 38  VAL A CG1 1 
ATOM   6660  C  CG2 . VAL E 1 56  ? 23.393  -33.056 17.65  1   38.92  ? 38  VAL A CG2 1 
ATOM   6661  N  N   . ARG E 1 57  ? 25.424  -35.581 14.182 1   39.81  ? 39  ARG A N   1 
ATOM   6662  C  CA  . ARG E 1 57  ? 25.862  -36.724 13.343 1   41.02  ? 39  ARG A CA  1 
ATOM   6663  C  C   . ARG E 1 57  ? 27.1    -37.366 13.96  1   41.88  ? 39  ARG A C   1 
ATOM   6664  O  O   . ARG E 1 57  ? 27.833  -36.67  14.682 1   42.85  ? 39  ARG A O   1 
ATOM   6665  C  CB  . ARG E 1 57  ? 26.114  -36.3   11.892 1   42.4   ? 39  ARG A CB  1 
ATOM   6666  C  CG  . ARG E 1 57  ? 27.417  -35.559 11.629 1   42.85  ? 39  ARG A CG  1 
ATOM   6667  C  CD  . ARG E 1 57  ? 27.567  -35.345 10.136 1   44.91  ? 39  ARG A CD  1 
ATOM   6668  N  NE  . ARG E 1 57  ? 28.59   -34.369 9.785  1   46.32  ? 39  ARG A NE  1 
ATOM   6669  C  CZ  . ARG E 1 57  ? 28.87   -33.975 8.545  1   47.44  ? 39  ARG A CZ  1 
ATOM   6670  N  NH1 . ARG E 1 57  ? 28.204  -34.465 7.511  1   47.99  ? 39  ARG A NH1 1 
ATOM   6671  N  NH2 . ARG E 1 57  ? 29.817  -33.077 8.34   1   50.48  ? 39  ARG A NH2 1 
ATOM   6672  N  N   . GLN E 1 58  ? 27.312  -38.644 13.652 1   40.98  ? 40  GLN A N   1 
ATOM   6673  C  CA  . GLN E 1 58  ? 28.453  -39.446 14.155 1   42.22  ? 40  GLN A CA  1 
ATOM   6674  C  C   . GLN E 1 58  ? 28.856  -40.451 13.072 1   42.43  ? 40  GLN A C   1 
ATOM   6675  O  O   . GLN E 1 58  ? 28.109  -41.437 12.866 1   41.5   ? 40  GLN A O   1 
ATOM   6676  C  CB  . GLN E 1 58  ? 28.052  -40.119 15.469 1   41.81  ? 40  GLN A CB  1 
ATOM   6677  C  CG  . GLN E 1 58  ? 29.203  -40.824 16.165 1   41.07  ? 40  GLN A CG  1 
ATOM   6678  C  CD  . GLN E 1 58  ? 28.786  -41.396 17.496 1   41.05  ? 40  GLN A CD  1 
ATOM   6679  O  OE1 . GLN E 1 58  ? 27.669  -41.881 17.661 1   41.22  ? 40  GLN A OE1 1 
ATOM   6680  N  NE2 . GLN E 1 58  ? 29.69   -41.35  18.459 1   42.02  ? 40  GLN A NE2 1 
ATOM   6681  N  N   . ALA E 1 59  ? 29.969  -40.185 12.383 1   43.73  ? 41  ALA A N   1 
ATOM   6682  C  CA  . ALA E 1 59  ? 30.583  -41.1   11.392 1   46.31  ? 41  ALA A CA  1 
ATOM   6683  C  C   . ALA E 1 59  ? 30.969  -42.391 12.11  1   47.66  ? 41  ALA A C   1 
ATOM   6684  O  O   . ALA E 1 59  ? 31.341  -42.346 13.281 1   45.64  ? 41  ALA A O   1 
ATOM   6685  C  CB  . ALA E 1 59  ? 31.772  -40.446 10.731 1   46.1   ? 41  ALA A CB  1 
ATOM   6686  N  N   . PRO E 1 60  ? 30.887  -43.574 11.455 1   51.53  ? 42  PRO A N   1 
ATOM   6687  C  CA  . PRO E 1 60  ? 31.106  -44.845 12.149 1   52.15  ? 42  PRO A CA  1 
ATOM   6688  C  C   . PRO E 1 60  ? 32.512  -44.89  12.773 1   52.09  ? 42  PRO A C   1 
ATOM   6689  O  O   . PRO E 1 60  ? 33.465  -44.613 12.066 1   54.29  ? 42  PRO A O   1 
ATOM   6690  C  CB  . PRO E 1 60  ? 30.892  -45.914 11.064 1   52.64  ? 42  PRO A CB  1 
ATOM   6691  C  CG  . PRO E 1 60  ? 31.078  -45.175 9.75   1   53.47  ? 42  PRO A CG  1 
ATOM   6692  C  CD  . PRO E 1 60  ? 30.62   -43.757 10.019 1   53.11  ? 42  PRO A CD  1 
ATOM   6693  N  N   . GLY E 1 61  ? 32.584  -45.145 14.086 1   50.49  ? 43  GLY A N   1 
ATOM   6694  C  CA  . GLY E 1 61  ? 33.835  -45.248 14.863 1   48.27  ? 43  GLY A CA  1 
ATOM   6695  C  C   . GLY E 1 61  ? 34.305  -43.922 15.449 1   48.26  ? 43  GLY A C   1 
ATOM   6696  O  O   . GLY E 1 61  ? 35.208  -43.971 16.303 1   50.28  ? 43  GLY A O   1 
ATOM   6697  N  N   . LYS E 1 62  ? 33.73   -42.782 15.043 1   48.35  ? 44  LYS A N   1 
ATOM   6698  C  CA  . LYS E 1 62  ? 34.269  -41.422 15.335 1   49.63  ? 44  LYS A CA  1 
ATOM   6699  C  C   . LYS E 1 62  ? 33.312  -40.669 16.271 1   47.69  ? 44  LYS A C   1 
ATOM   6700  O  O   . LYS E 1 62  ? 32.405  -41.319 16.841 1   46.56  ? 44  LYS A O   1 
ATOM   6701  C  CB  . LYS E 1 62  ? 34.574  -40.723 14.007 1   53.17  ? 44  LYS A CB  1 
ATOM   6702  C  CG  . LYS E 1 62  ? 35.718  -41.364 13.232 1   58.6   ? 44  LYS A CG  1 
ATOM   6703  C  CD  . LYS E 1 62  ? 35.953  -40.77  11.86  1   65.1   ? 44  LYS A CD  1 
ATOM   6704  C  CE  . LYS E 1 62  ? 36.897  -41.6   11.013 1   68.69  ? 44  LYS A CE  1 
ATOM   6705  N  NZ  . LYS E 1 62  ? 36.885  -41.168 9.594  1   71.49  ? 44  LYS A NZ  1 
ATOM   6706  N  N   . GLY E 1 63  ? 33.54   -39.365 16.471 1   46.62  ? 45  GLY A N   1 
ATOM   6707  C  CA  . GLY E 1 63  ? 32.914  -38.555 17.536 1   46.21  ? 45  GLY A CA  1 
ATOM   6708  C  C   . GLY E 1 63  ? 31.649  -37.843 17.087 1   45.19  ? 45  GLY A C   1 
ATOM   6709  O  O   . GLY E 1 63  ? 31.368  -37.822 15.874 1   46.54  ? 45  GLY A O   1 
ATOM   6710  N  N   . LEU E 1 64  ? 30.92   -37.263 18.045 1   45.39  ? 46  LEU A N   1 
ATOM   6711  C  CA  . LEU E 1 64  ? 29.67   -36.49  17.81  1   43.51  ? 46  LEU A CA  1 
ATOM   6712  C  C   . LEU E 1 64  ? 30.04   -35.15  17.171 1   43.68  ? 46  LEU A C   1 
ATOM   6713  O  O   . LEU E 1 64  ? 31.005  -34.513 17.645 1   43.98  ? 46  LEU A O   1 
ATOM   6714  C  CB  . LEU E 1 64  ? 28.92   -36.266 19.129 1   42.03  ? 46  LEU A CB  1 
ATOM   6715  C  CG  . LEU E 1 64  ? 28.505  -37.52  19.897 1   41.88  ? 46  LEU A CG  1 
ATOM   6716  C  CD1 . LEU E 1 64  ? 27.849  -37.144 21.215 1   41.23  ? 46  LEU A CD1 1 
ATOM   6717  C  CD2 . LEU E 1 64  ? 27.571  -38.394 19.074 1   42.52  ? 46  LEU A CD2 1 
ATOM   6718  N  N   . GLU E 1 65  ? 29.314  -34.771 16.117 1   43.37  ? 47  GLU A N   1 
ATOM   6719  C  CA  . GLU E 1 65  ? 29.432  -33.466 15.426 1   43.05  ? 47  GLU A CA  1 
ATOM   6720  C  C   . GLU E 1 65  ? 28.031  -32.867 15.295 1   41.6   ? 47  GLU A C   1 
ATOM   6721  O  O   . GLU E 1 65  ? 27.21   -33.43  14.558 1   40.68  ? 47  GLU A O   1 
ATOM   6722  C  CB  . GLU E 1 65  ? 30.092  -33.616 14.054 1   45.24  ? 47  GLU A CB  1 
ATOM   6723  C  CG  . GLU E 1 65  ? 30.477  -32.282 13.432 1   46.43  ? 47  GLU A CG  1 
ATOM   6724  C  CD  . GLU E 1 65  ? 30.935  -32.32  11.983 1   48.12  ? 47  GLU A CD  1 
ATOM   6725  O  OE1 . GLU E 1 65  ? 30.886  -33.406 11.361 1   44.93  ? 47  GLU A OE1 1 
ATOM   6726  O  OE2 . GLU E 1 65  ? 31.341  -31.251 11.479 1   51.19  ? 47  GLU A OE2 1 
ATOM   6727  N  N   . TRP E 1 66  ? 27.782  -31.768 16.005 1   41.74  ? 48  TRP A N   1 
ATOM   6728  C  CA  . TRP E 1 66  ? 26.614  -30.882 15.786 1   41.57  ? 48  TRP A CA  1 
ATOM   6729  C  C   . TRP E 1 66  ? 26.594  -30.444 14.317 1   43.3   ? 48  TRP A C   1 
ATOM   6730  O  O   . TRP E 1 66  ? 27.661  -30.031 13.811 1   44     ? 48  TRP A O   1 
ATOM   6731  C  CB  . TRP E 1 66  ? 26.684  -29.683 16.73  1   41.38  ? 48  TRP A CB  1 
ATOM   6732  C  CG  . TRP E 1 66  ? 25.59   -28.698 16.493 1   41.81  ? 48  TRP A CG  1 
ATOM   6733  C  CD1 . TRP E 1 66  ? 24.298  -28.791 16.912 1   42.33  ? 48  TRP A CD1 1 
ATOM   6734  C  CD2 . TRP E 1 66  ? 25.683  -27.485 15.73  1   42.58  ? 48  TRP A CD2 1 
ATOM   6735  N  NE1 . TRP E 1 66  ? 23.583  -27.711 16.476 1   42.8   ? 48  TRP A NE1 1 
ATOM   6736  C  CE2 . TRP E 1 66  ? 24.405  -26.891 15.75  1   42.31  ? 48  TRP A CE2 1 
ATOM   6737  C  CE3 . TRP E 1 66  ? 26.719  -26.84  15.044 1   43.46  ? 48  TRP A CE3 1 
ATOM   6738  C  CZ2 . TRP E 1 66  ? 24.14   -25.681 15.108 1   43.38  ? 48  TRP A CZ2 1 
ATOM   6739  C  CZ3 . TRP E 1 66  ? 26.454  -25.646 14.407 1   44.11  ? 48  TRP A CZ3 1 
ATOM   6740  C  CH2 . TRP E 1 66  ? 25.181  -25.074 14.443 1   42.42  ? 48  TRP A CH2 1 
ATOM   6741  N  N   . VAL E 1 67  ? 25.429  -30.55  13.67  1   45.22  ? 49  VAL A N   1 
ATOM   6742  C  CA  . VAL E 1 67  ? 25.22   -30.288 12.215 1   46.81  ? 49  VAL A CA  1 
ATOM   6743  C  C   . VAL E 1 67  ? 24.429  -28.984 12.07  1   47.2   ? 49  VAL A C   1 
ATOM   6744  O  O   . VAL E 1 67  ? 24.947  -28.049 11.432 1   45.72  ? 49  VAL A O   1 
ATOM   6745  C  CB  . VAL E 1 67  ? 24.508  -31.478 11.538 1   48.44  ? 49  VAL A CB  1 
ATOM   6746  C  CG1 . VAL E 1 67  ? 24.055  -31.169 10.118 1   49.49  ? 49  VAL A CG1 1 
ATOM   6747  C  CG2 . VAL E 1 67  ? 25.386  -32.718 11.543 1   49.66  ? 49  VAL A CG2 1 
ATOM   6748  N  N   . SER E 1 68  ? 23.211  -28.945 12.616 1   46.33  ? 50  SER A N   1 
ATOM   6749  C  CA  . SER E 1 68  ? 22.27   -27.804 12.491 1   47.73  ? 50  SER A CA  1 
ATOM   6750  C  C   . SER E 1 68  ? 21.413  -27.663 13.748 1   47.55  ? 50  SER A C   1 
ATOM   6751  O  O   . SER E 1 68  ? 21.114  -28.683 14.391 1   46.87  ? 50  SER A O   1 
ATOM   6752  C  CB  . SER E 1 68  ? 21.395  -27.949 11.281 1   50.79  ? 50  SER A CB  1 
ATOM   6753  O  OG  . SER E 1 68  ? 22.176  -28.186 10.122 1   56.57  ? 50  SER A OG  1 
ATOM   6754  N  N   . SER E 1 69  ? 21.049  -26.424 14.068 1   46.38  ? 51  SER A N   1 
ATOM   6755  C  CA  . SER E 1 69  ? 19.999  -26.061 15.049 1   45.87  ? 51  SER A CA  1 
ATOM   6756  C  C   . SER E 1 69  ? 18.94   -25.239 14.317 1   46.07  ? 51  SER A C   1 
ATOM   6757  O  O   . SER E 1 69  ? 19.304  -24.553 13.34  1   46.47  ? 51  SER A O   1 
ATOM   6758  C  CB  . SER E 1 69  ? 20.557  -25.294 16.214 1   47.19  ? 51  SER A CB  1 
ATOM   6759  O  OG  . SER E 1 69  ? 21.219  -26.146 17.131 1   45.05  ? 51  SER A OG  1 
ATOM   6760  N  N   . ILE E 1 70  ? 17.688  -25.344 14.76  1   44.59  ? 52  ILE A N   1 
ATOM   6761  C  CA  . ILE E 1 70  ? 16.578  -24.418 14.396 1   44.5   ? 52  ILE A CA  1 
ATOM   6762  C  C   . ILE E 1 70  ? 15.945  -23.951 15.712 1   43.63  ? 52  ILE A C   1 
ATOM   6763  O  O   . ILE E 1 70  ? 15.554  -24.807 16.526 1   41.94  ? 52  ILE A O   1 
ATOM   6764  C  CB  . ILE E 1 70  ? 15.581  -25.07  13.409 1   46.18  ? 52  ILE A CB  1 
ATOM   6765  C  CG1 . ILE E 1 70  ? 14.52   -24.071 12.933 1   47.3   ? 52  ILE A CG1 1 
ATOM   6766  C  CG2 . ILE E 1 70  ? 14.95   -26.335 13.978 1   45.89  ? 52  ILE A CG2 1 
ATOM   6767  C  CD1 . ILE E 1 70  ? 13.748  -24.513 11.709 1   47.15  ? 52  ILE A CD1 1 
ATOM   6768  N  N   . TYR E 1 71  ? 15.909  -22.634 15.929 1   44.16  ? 53  TYR A N   1 
ATOM   6769  C  CA  . TYR E 1 71  ? 15.439  -21.998 17.187 1   43.16  ? 53  TYR A CA  1 
ATOM   6770  C  C   . TYR E 1 71  ? 13.909  -22.041 17.227 1   43.63  ? 53  TYR A C   1 
ATOM   6771  O  O   . TYR E 1 71  ? 13.271  -22.363 16.197 1   42.63  ? 53  TYR A O   1 
ATOM   6772  C  CB  . TYR E 1 71  ? 16.013  -20.582 17.336 1   43.08  ? 53  TYR A CB  1 
ATOM   6773  C  CG  . TYR E 1 71  ? 17.336  -20.527 18.057 1   42.19  ? 53  TYR A CG  1 
ATOM   6774  C  CD1 . TYR E 1 71  ? 17.393  -20.436 19.44  1   42     ? 53  TYR A CD1 1 
ATOM   6775  C  CD2 . TYR E 1 71  ? 18.533  -20.598 17.362 1   42.26  ? 53  TYR A CD2 1 
ATOM   6776  C  CE1 . TYR E 1 71  ? 18.604  -20.416 20.115 1   41.41  ? 53  TYR A CE1 1 
ATOM   6777  C  CE2 . TYR E 1 71  ? 19.752  -20.573 18.02  1   42.7   ? 53  TYR A CE2 1 
ATOM   6778  C  CZ  . TYR E 1 71  ? 19.788  -20.477 19.402 1   43.36  ? 53  TYR A CZ  1 
ATOM   6779  O  OH  . TYR E 1 71  ? 20.991  -20.444 20.05  1   46.7   ? 53  TYR A OH  1 
ATOM   6780  N  N   . HIS E 1 72  ? 13.355  -21.689 18.39  1   43.42  ? 54  HIS A N   1 
ATOM   6781  C  CA  . HIS E 1 72  ? 11.922  -21.825 18.757 1   45.87  ? 54  HIS A CA  1 
ATOM   6782  C  C   . HIS E 1 72  ? 11.069  -21.075 17.73  1   50.99  ? 54  HIS A C   1 
ATOM   6783  O  O   . HIS E 1 72  ? 11.471  -19.956 17.36  1   57.1   ? 54  HIS A O   1 
ATOM   6784  C  CB  . HIS E 1 72  ? 11.641  -21.263 20.16  1   44.99  ? 54  HIS A CB  1 
ATOM   6785  C  CG  . HIS E 1 72  ? 12.504  -21.787 21.261 1   43.66  ? 54  HIS A CG  1 
ATOM   6786  N  ND1 . HIS E 1 72  ? 13.891  -21.778 21.199 1   42.45  ? 54  HIS A ND1 1 
ATOM   6787  C  CD2 . HIS E 1 72  ? 12.181  -22.276 22.476 1   42.02  ? 54  HIS A CD2 1 
ATOM   6788  C  CE1 . HIS E 1 72  ? 14.381  -22.263 22.317 1   42.12  ? 54  HIS A CE1 1 
ATOM   6789  N  NE2 . HIS E 1 72  ? 13.348  -22.579 23.118 1   43.61  ? 54  HIS A NE2 1 
ATOM   6790  N  N   . TYR E 1 73  ? 9.976   -21.688 17.257 1   54.29  ? 55  TYR A N   1 
ATOM   6791  C  CA  . TYR E 1 73  ? 8.858   -21.054 16.503 1   54.68  ? 55  TYR A CA  1 
ATOM   6792  C  C   . TYR E 1 73  ? 9.27    -20.684 15.073 1   54.21  ? 55  TYR A C   1 
ATOM   6793  O  O   . TYR E 1 73  ? 8.63    -21.174 14.138 1   55.91  ? 55  TYR A O   1 
ATOM   6794  C  CB  . TYR E 1 73  ? 8.322   -19.847 17.276 1   55.55  ? 55  TYR A CB  1 
ATOM   6795  C  CG  . TYR E 1 73  ? 7.863   -20.202 18.666 1   56.35  ? 55  TYR A CG  1 
ATOM   6796  C  CD1 . TYR E 1 73  ? 6.781   -21.047 18.843 1   57.58  ? 55  TYR A CD1 1 
ATOM   6797  C  CD2 . TYR E 1 73  ? 8.52    -19.738 19.796 1   56.75  ? 55  TYR A CD2 1 
ATOM   6798  C  CE1 . TYR E 1 73  ? 6.343   -21.41  20.105 1   58.99  ? 55  TYR A CE1 1 
ATOM   6799  C  CE2 . TYR E 1 73  ? 8.093   -20.087 21.069 1   57.46  ? 55  TYR A CE2 1 
ATOM   6800  C  CZ  . TYR E 1 73  ? 7.001   -20.928 21.222 1   58.57  ? 55  TYR A CZ  1 
ATOM   6801  O  OH  . TYR E 1 73  ? 6.544   -21.3   22.45  1   58.14  ? 55  TYR A OH  1 
ATOM   6802  N  N   . GLY E 1 74  ? 10.278  -19.828 14.906 1   57.36  ? 56  GLY A N   1 
ATOM   6803  C  CA  . GLY E 1 74  ? 10.688  -19.29  13.594 1   62.08  ? 56  GLY A CA  1 
ATOM   6804  C  C   . GLY E 1 74  ? 11.442  -20.297 12.737 1   64.05  ? 56  GLY A C   1 
ATOM   6805  O  O   . GLY E 1 74  ? 11.456  -21.499 13.084 1   66.58  ? 56  GLY A O   1 
ATOM   6806  N  N   . HIS E 1 75  ? 12.029  -19.809 11.639 1   63.53  ? 57  HIS A N   1 
ATOM   6807  C  CA  . HIS E 1 75  ? 12.899  -20.562 10.696 1   64.19  ? 57  HIS A CA  1 
ATOM   6808  C  C   . HIS E 1 75  ? 14.328  -19.999 10.741 1   59.91  ? 57  HIS A C   1 
ATOM   6809  O  O   . HIS E 1 75  ? 14.997  -19.98  9.68   1   55.61  ? 57  HIS A O   1 
ATOM   6810  C  CB  . HIS E 1 75  ? 12.299  -20.532 9.28   1   71.33  ? 57  HIS A CB  1 
ATOM   6811  C  CG  . HIS E 1 75  ? 10.837  -20.836 9.229  1   79.16  ? 57  HIS A CG  1 
ATOM   6812  N  ND1 . HIS E 1 75  ? 10.251  -21.798 10.035 1   85.69  ? 57  HIS A ND1 1 
ATOM   6813  C  CD2 . HIS E 1 75  ? 9.843   -20.319 8.474  1   83.88  ? 57  HIS A CD2 1 
ATOM   6814  C  CE1 . HIS E 1 75  ? 8.958   -21.853 9.784  1   87.55  ? 57  HIS A CE1 1 
ATOM   6815  N  NE2 . HIS E 1 75  ? 8.682   -20.954 8.829  1   89.49  ? 57  HIS A NE2 1 
ATOM   6816  N  N   A ASN E 1 76  ? 14.779  -19.556 11.924 0.5 58.37  ? 58  ASN A N   1 
ATOM   6817  N  N   B ASN E 1 76  ? 14.781  -19.574 11.929 0.5 59.04  ? 58  ASN A N   1 
ATOM   6818  C  CA  A ASN E 1 76  ? 16.156  -19.046 12.166 0.5 57.61  ? 58  ASN A CA  1 
ATOM   6819  C  CA  B ASN E 1 76  ? 16.149  -19.048 12.187 0.5 58.68  ? 58  ASN A CA  1 
ATOM   6820  C  C   A ASN E 1 76  ? 17.064  -20.24  12.476 0.5 57.42  ? 58  ASN A C   1 
ATOM   6821  C  C   B ASN E 1 76  ? 17.074  -20.234 12.486 0.5 58.04  ? 58  ASN A C   1 
ATOM   6822  O  O   A ASN E 1 76  ? 16.957  -20.794 13.59  0.5 58.23  ? 58  ASN A O   1 
ATOM   6823  O  O   B ASN E 1 76  ? 16.99   -20.781 13.605 0.5 58.78  ? 58  ASN A O   1 
ATOM   6824  C  CB  A ASN E 1 76  ? 16.215  -18.009 13.29  0.5 56.31  ? 58  ASN A CB  1 
ATOM   6825  C  CB  B ASN E 1 76  ? 16.157  -18.024 13.327 0.5 58.18  ? 58  ASN A CB  1 
ATOM   6826  C  CG  A ASN E 1 76  ? 17.566  -17.329 13.377 0.5 54.88  ? 58  ASN A CG  1 
ATOM   6827  C  CG  B ASN E 1 76  ? 15.432  -16.74  12.98  0.5 57.49  ? 58  ASN A CG  1 
ATOM   6828  O  OD1 A ASN E 1 76  ? 18.143  -16.949 12.358 0.5 52.89  ? 58  ASN A OD1 1 
ATOM   6829  O  OD1 B ASN E 1 76  ? 15.592  -16.203 11.885 0.5 57.29  ? 58  ASN A OD1 1 
ATOM   6830  N  ND2 A ASN E 1 76  ? 18.081  -17.175 14.586 0.5 54.27  ? 58  ASN A ND2 1 
ATOM   6831  N  ND2 B ASN E 1 76  ? 14.635  -16.238 13.909 0.5 56.29  ? 58  ASN A ND2 1 
ATOM   6832  N  N   . ALA E 1 77  ? 17.913  -20.613 11.516 1   56.76  ? 59  ALA A N   1 
ATOM   6833  C  CA  . ALA E 1 77  ? 18.763  -21.821 11.556 1   55.71  ? 59  ALA A CA  1 
ATOM   6834  C  C   . ALA E 1 77  ? 20.236  -21.429 11.687 1   56.97  ? 59  ALA A C   1 
ATOM   6835  O  O   . ALA E 1 77  ? 20.616  -20.339 11.207 1   54.92  ? 59  ALA A O   1 
ATOM   6836  C  CB  . ALA E 1 77  ? 18.53   -22.633 10.309 1   56.16  ? 59  ALA A CB  1 
ATOM   6837  N  N   . TYR E 1 78  ? 21.021  -22.307 12.317 1   56.98  ? 60  TYR A N   1 
ATOM   6838  C  CA  . TYR E 1 78  ? 22.503  -22.25  12.392 1   56.18  ? 60  TYR A CA  1 
ATOM   6839  C  C   . TYR E 1 78  ? 23.059  -23.597 11.923 1   54.3   ? 60  TYR A C   1 
ATOM   6840  O  O   . TYR E 1 78  ? 22.36   -24.619 12.066 1   54.72  ? 60  TYR A O   1 
ATOM   6841  C  CB  . TYR E 1 78  ? 22.938  -21.844 13.8   1   58.34  ? 60  TYR A CB  1 
ATOM   6842  C  CG  . TYR E 1 78  ? 22.563  -20.425 14.137 1   61.72  ? 60  TYR A CG  1 
ATOM   6843  C  CD1 . TYR E 1 78  ? 23.397  -19.365 13.806 1   63.93  ? 60  TYR A CD1 1 
ATOM   6844  C  CD2 . TYR E 1 78  ? 21.351  -20.133 14.746 1   63.38  ? 60  TYR A CD2 1 
ATOM   6845  C  CE1 . TYR E 1 78  ? 23.049  -18.054 14.094 1   65.83  ? 60  TYR A CE1 1 
ATOM   6846  C  CE2 . TYR E 1 78  ? 20.988  -18.829 15.04  1   66.37  ? 60  TYR A CE2 1 
ATOM   6847  C  CZ  . TYR E 1 78  ? 21.839  -17.786 14.714 1   67.69  ? 60  TYR A CZ  1 
ATOM   6848  O  OH  . TYR E 1 78  ? 21.481  -16.503 15.01  1   70.47  ? 60  TYR A OH  1 
ATOM   6849  N  N   . TYR E 1 79  ? 24.258  -23.569 11.332 1   51.09  ? 61  TYR A N   1 
ATOM   6850  C  CA  . TYR E 1 79  ? 24.913  -24.714 10.649 1   49.4   ? 61  TYR A CA  1 
ATOM   6851  C  C   . TYR E 1 79  ? 26.395  -24.763 11.036 1   49.11  ? 61  TYR A C   1 
ATOM   6852  O  O   . TYR E 1 79  ? 27.005  -23.698 11.197 1   52.07  ? 61  TYR A O   1 
ATOM   6853  C  CB  . TYR E 1 79  ? 24.739  -24.584 9.132  1   48.91  ? 61  TYR A CB  1 
ATOM   6854  C  CG  . TYR E 1 79  ? 23.305  -24.517 8.667  1   49.77  ? 61  TYR A CG  1 
ATOM   6855  C  CD1 . TYR E 1 79  ? 22.609  -23.315 8.65   1   49.86  ? 61  TYR A CD1 1 
ATOM   6856  C  CD2 . TYR E 1 79  ? 22.632  -25.655 8.25   1   48.88  ? 61  TYR A CD2 1 
ATOM   6857  C  CE1 . TYR E 1 79  ? 21.286  -23.246 8.239  1   49.37  ? 61  TYR A CE1 1 
ATOM   6858  C  CE2 . TYR E 1 79  ? 21.311  -25.602 7.831  1   48.72  ? 61  TYR A CE2 1 
ATOM   6859  C  CZ  . TYR E 1 79  ? 20.632  -24.394 7.826  1   49.14  ? 61  TYR A CZ  1 
ATOM   6860  O  OH  . TYR E 1 79  ? 19.33   -24.322 7.415  1   47.61  ? 61  TYR A OH  1 
ATOM   6861  N  N   . ALA E 1 80  ? 26.95   -25.968 11.193 1   49.33  ? 62  ALA A N   1 
ATOM   6862  C  CA  . ALA E 1 80  ? 28.409  -26.228 11.207 1   50.73  ? 62  ALA A CA  1 
ATOM   6863  C  C   . ALA E 1 80  ? 28.999  -25.839 9.843  1   52.52  ? 62  ALA A C   1 
ATOM   6864  O  O   . ALA E 1 80  ? 28.314  -26.049 8.822  1   51.1   ? 62  ALA A O   1 
ATOM   6865  C  CB  . ALA E 1 80  ? 28.679  -27.677 11.526 1   51.06  ? 62  ALA A CB  1 
ATOM   6866  N  N   . ASP E 1 81  ? 30.222  -25.298 9.832  1   56.65  ? 63  ASP A N   1 
ATOM   6867  C  CA  . ASP E 1 81  ? 30.917  -24.792 8.614  1   58.85  ? 63  ASP A CA  1 
ATOM   6868  C  C   . ASP E 1 81  ? 31.222  -25.957 7.663  1   59.99  ? 63  ASP A C   1 
ATOM   6869  O  O   . ASP E 1 81  ? 31.19   -25.726 6.434  1   60.69  ? 63  ASP A O   1 
ATOM   6870  C  CB  . ASP E 1 81  ? 32.18   -24.002 8.976  1   60.61  ? 63  ASP A CB  1 
ATOM   6871  C  CG  . ASP E 1 81  ? 31.899  -22.673 9.665  1   62.4   ? 63  ASP A CG  1 
ATOM   6872  O  OD1 . ASP E 1 81  ? 30.944  -21.978 9.246  1   60.93  ? 63  ASP A OD1 1 
ATOM   6873  O  OD2 . ASP E 1 81  ? 32.632  -22.343 10.619 1   62.42  ? 63  ASP A OD2 1 
ATOM   6874  N  N   . SER E 1 82  ? 31.456  -27.163 8.201  1   59.9   ? 64  SER A N   1 
ATOM   6875  C  CA  . SER E 1 82  ? 31.631  -28.433 7.437  1   59.25  ? 64  SER A CA  1 
ATOM   6876  C  C   . SER E 1 82  ? 30.406  -28.733 6.558  1   56.56  ? 64  SER A C   1 
ATOM   6877  O  O   . SER E 1 82  ? 30.547  -29.541 5.618  1   54.59  ? 64  SER A O   1 
ATOM   6878  C  CB  . SER E 1 82  ? 31.912  -29.59  8.367  1   58.4   ? 64  SER A CB  1 
ATOM   6879  O  OG  . SER E 1 82  ? 30.784  -29.861 9.188  1   59.14  ? 64  SER A OG  1 
ATOM   6880  N  N   . VAL E 1 83  ? 29.258  -28.117 6.864  1   55.79  ? 65  VAL A N   1 
ATOM   6881  C  CA  . VAL E 1 83  ? 27.916  -28.417 6.282  1   56.29  ? 65  VAL A CA  1 
ATOM   6882  C  C   . VAL E 1 83  ? 27.302  -27.167 5.614  1   54.3   ? 65  VAL A C   1 
ATOM   6883  O  O   . VAL E 1 83  ? 26.285  -27.332 4.906  1   50.71  ? 65  VAL A O   1 
ATOM   6884  C  CB  . VAL E 1 83  ? 27.05   -29.039 7.406  1   57.19  ? 65  VAL A CB  1 
ATOM   6885  C  CG1 . VAL E 1 83  ? 25.706  -28.365 7.641  1   56.71  ? 65  VAL A CG1 1 
ATOM   6886  C  CG2 . VAL E 1 83  ? 26.883  -30.535 7.2    1   57.39  ? 65  VAL A CG2 1 
ATOM   6887  N  N   . LYS E 1 84  ? 27.907  -25.98  5.762  1   57.93  ? 66  LYS A N   1 
ATOM   6888  C  CA  . LYS E 1 84  ? 27.32   -24.677 5.331  1   60.18  ? 66  LYS A CA  1 
ATOM   6889  C  C   . LYS E 1 84  ? 27.202  -24.631 3.799  1   59.53  ? 66  LYS A C   1 
ATOM   6890  O  O   . LYS E 1 84  ? 28.128  -25.115 3.112  1   59.78  ? 66  LYS A O   1 
ATOM   6891  C  CB  . LYS E 1 84  ? 28.161  -23.501 5.842  1   63.47  ? 66  LYS A CB  1 
ATOM   6892  C  CG  . LYS E 1 84  ? 27.453  -22.151 5.858  1   67.12  ? 66  LYS A CG  1 
ATOM   6893  C  CD  . LYS E 1 84  ? 28.404  -20.965 5.881  1   68.91  ? 66  LYS A CD  1 
ATOM   6894  C  CE  . LYS E 1 84  ? 27.675  -19.638 5.961  0   69.19  ? 66  LYS A CE  1 
ATOM   6895  N  NZ  . LYS E 1 84  ? 28.622  -18.498 5.972  0   69.25  ? 66  LYS A NZ  1 
ATOM   6896  N  N   . GLY E 1 85  ? 26.089  -24.088 3.294  1   58.43  ? 67  GLY A N   1 
ATOM   6897  C  CA  . GLY E 1 85  ? 25.806  -23.923 1.854  1   59.99  ? 67  GLY A CA  1 
ATOM   6898  C  C   . GLY E 1 85  ? 25.337  -25.204 1.172  1   61.6   ? 67  GLY A C   1 
ATOM   6899  O  O   . GLY E 1 85  ? 25.181  -25.172 -0.067 1   65.69  ? 67  GLY A O   1 
ATOM   6900  N  N   . ARG E 1 86  ? 25.092  -26.281 1.93   1   61.54  ? 68  ARG A N   1 
ATOM   6901  C  CA  . ARG E 1 86  ? 24.718  -27.627 1.407  1   56.89  ? 68  ARG A CA  1 
ATOM   6902  C  C   . ARG E 1 86  ? 23.456  -28.136 2.113  1   54.06  ? 68  ARG A C   1 
ATOM   6903  O  O   . ARG E 1 86  ? 22.464  -28.434 1.411  1   54.86  ? 68  ARG A O   1 
ATOM   6904  C  CB  . ARG E 1 86  ? 25.882  -28.601 1.597  1   55.59  ? 68  ARG A CB  1 
ATOM   6905  C  CG  . ARG E 1 86  ? 27.123  -28.225 0.805  1   56.14  ? 68  ARG A CG  1 
ATOM   6906  C  CD  . ARG E 1 86  ? 28.087  -29.38  0.652  1   56.61  ? 68  ARG A CD  1 
ATOM   6907  N  NE  . ARG E 1 86  ? 28.643  -29.795 1.941  1   58.84  ? 68  ARG A NE  1 
ATOM   6908  C  CZ  . ARG E 1 86  ? 28.619  -31.03  2.462  1   56.85  ? 68  ARG A CZ  1 
ATOM   6909  N  NH1 . ARG E 1 86  ? 28.071  -32.051 1.815  1   55.69  ? 68  ARG A NH1 1 
ATOM   6910  N  NH2 . ARG E 1 86  ? 29.169  -31.238 3.648  1   54.67  ? 68  ARG A NH2 1 
ATOM   6911  N  N   . PHE E 1 87  ? 23.499  -28.242 3.444  1   51.38  ? 69  PHE A N   1 
ATOM   6912  C  CA  . PHE E 1 87  ? 22.391  -28.777 4.281  1   50.71  ? 69  PHE A CA  1 
ATOM   6913  C  C   . PHE E 1 87  ? 21.426  -27.64  4.632  1   48.29  ? 69  PHE A C   1 
ATOM   6914  O  O   . PHE E 1 87  ? 21.875  -26.491 4.743  1   48.19  ? 69  PHE A O   1 
ATOM   6915  C  CB  . PHE E 1 87  ? 22.9    -29.43  5.57   1   48.67  ? 69  PHE A CB  1 
ATOM   6916  C  CG  . PHE E 1 87  ? 23.708  -30.699 5.434  1   48.3   ? 69  PHE A CG  1 
ATOM   6917  C  CD1 . PHE E 1 87  ? 24.383  -31.037 4.266  1   48.66  ? 69  PHE A CD1 1 
ATOM   6918  C  CD2 . PHE E 1 87  ? 23.819  -31.557 6.519  1   49.37  ? 69  PHE A CD2 1 
ATOM   6919  C  CE1 . PHE E 1 87  ? 25.123  -32.209 4.181  1   50.23  ? 69  PHE A CE1 1 
ATOM   6920  C  CE2 . PHE E 1 87  ? 24.566  -32.724 6.436  1   49.7   ? 69  PHE A CE2 1 
ATOM   6921  C  CZ  . PHE E 1 87  ? 25.218  -33.05  5.267  1   50.38  ? 69  PHE A CZ  1 
ATOM   6922  N  N   . THR E 1 88  ? 20.145  -27.973 4.81   1   49.28  ? 70  THR A N   1 
ATOM   6923  C  CA  . THR E 1 88  ? 19.058  -27.056 5.249  1   49.09  ? 70  THR A CA  1 
ATOM   6924  C  C   . THR E 1 88  ? 18.18   -27.771 6.285  1   50.12  ? 70  THR A C   1 
ATOM   6925  O  O   . THR E 1 88  ? 17.564  -28.803 5.924  1   50.46  ? 70  THR A O   1 
ATOM   6926  C  CB  . THR E 1 88  ? 18.215  -26.573 4.061  1   47.46  ? 70  THR A CB  1 
ATOM   6927  O  OG1 . THR E 1 88  ? 19.11   -26.078 3.066  1   46.62  ? 70  THR A OG1 1 
ATOM   6928  C  CG2 . THR E 1 88  ? 17.214  -25.502 4.437  1   47.06  ? 70  THR A CG2 1 
ATOM   6929  N  N   . ILE E 1 89  ? 18.123  -27.234 7.511  1   49.94  ? 71  ILE A N   1 
ATOM   6930  C  CA  . ILE E 1 89  ? 17.214  -27.707 8.598  1   49.49  ? 71  ILE A CA  1 
ATOM   6931  C  C   . ILE E 1 89  ? 15.852  -27.034 8.391  1   50.37  ? 71  ILE A C   1 
ATOM   6932  O  O   . ILE E 1 89  ? 15.812  -25.793 8.3    1   50.3   ? 71  ILE A O   1 
ATOM   6933  C  CB  . ILE E 1 89  ? 17.804  -27.472 10.009 1   48.46  ? 71  ILE A CB  1 
ATOM   6934  C  CG1 . ILE E 1 89  ? 16.966  -28.178 11.08  1   49.66  ? 71  ILE A CG1 1 
ATOM   6935  C  CG2 . ILE E 1 89  ? 17.994  -25.995 10.333 1   47.03  ? 71  ILE A CG2 1 
ATOM   6936  C  CD1 . ILE E 1 89  ? 17.618  -28.24  12.446 1   50.54  ? 71  ILE A CD1 1 
ATOM   6937  N  N   . SER E 1 90  ? 14.793  -27.837 8.259  1   53.33  ? 72  SER A N   1 
ATOM   6938  C  CA  . SER E 1 90  ? 13.383  -27.389 8.097  1   55.67  ? 72  SER A CA  1 
ATOM   6939  C  C   . SER E 1 90  ? 12.562  -27.919 9.277  1   55.06  ? 72  SER A C   1 
ATOM   6940  O  O   . SER E 1 90  ? 13.014  -28.871 9.936  1   53.79  ? 72  SER A O   1 
ATOM   6941  C  CB  . SER E 1 90  ? 12.788  -27.838 6.774  1   56.82  ? 72  SER A CB  1 
ATOM   6942  O  OG  . SER E 1 90  ? 13.8    -28.142 5.82   1   62.1   ? 72  SER A OG  1 
ATOM   6943  N  N   . ARG E 1 91  ? 11.407  -27.305 9.526  1   56.42  ? 73  ARG A N   1 
ATOM   6944  C  CA  . ARG E 1 91  ? 10.394  -27.768 10.509 1   58.65  ? 73  ARG A CA  1 
ATOM   6945  C  C   . ARG E 1 91  ? 8.999   -27.582 9.893  1   59.19  ? 73  ARG A C   1 
ATOM   6946  O  O   . ARG E 1 91  ? 8.788   -26.562 9.21   1   63.88  ? 73  ARG A O   1 
ATOM   6947  C  CB  . ARG E 1 91  ? 10.58   -27.003 11.82  1   59.83  ? 73  ARG A CB  1 
ATOM   6948  C  CG  . ARG E 1 91  ? 9.719   -27.499 12.972 1   61.31  ? 73  ARG A CG  1 
ATOM   6949  C  CD  . ARG E 1 91  ? 9.636   -26.467 14.077 1   62.46  ? 73  ARG A CD  1 
ATOM   6950  N  NE  . ARG E 1 91  ? 10.811  -26.472 14.943 1   64.38  ? 73  ARG A NE  1 
ATOM   6951  C  CZ  . ARG E 1 91  ? 11.37   -25.401 15.516 1   65.42  ? 73  ARG A CZ  1 
ATOM   6952  N  NH1 . ARG E 1 91  ? 10.9    -24.179 15.301 1   65.67  ? 73  ARG A NH1 1 
ATOM   6953  N  NH2 . ARG E 1 91  ? 12.422  -25.558 16.304 1   64.22  ? 73  ARG A NH2 1 
ATOM   6954  N  N   . ASP E 1 92  ? 8.104   -28.552 10.106 1   60.63  ? 74  ASP A N   1 
ATOM   6955  C  CA  . ASP E 1 92  ? 6.703   -28.579 9.6    1   58.99  ? 74  ASP A CA  1 
ATOM   6956  C  C   . ASP E 1 92  ? 5.786   -28.859 10.792 1   57.96  ? 74  ASP A C   1 
ATOM   6957  O  O   . ASP E 1 92  ? 5.735   -30.022 11.236 1   57.89  ? 74  ASP A O   1 
ATOM   6958  C  CB  . ASP E 1 92  ? 6.546   -29.621 8.488  1   59.01  ? 74  ASP A CB  1 
ATOM   6959  C  CG  . ASP E 1 92  ? 5.199   -29.634 7.787  1   59.36  ? 74  ASP A CG  1 
ATOM   6960  O  OD1 . ASP E 1 92  ? 4.17    -29.474 8.474  1   58.12  ? 74  ASP A OD1 1 
ATOM   6961  O  OD2 . ASP E 1 92  ? 5.193   -29.822 6.552  1   61.01  ? 74  ASP A OD2 1 
ATOM   6962  N  N   . ASN E 1 93  ? 5.087   -27.833 11.276 1   58.43  ? 75  ASN A N   1 
ATOM   6963  C  CA  . ASN E 1 93  ? 4.388   -27.853 12.589 1   58.99  ? 75  ASN A CA  1 
ATOM   6964  C  C   . ASN E 1 93  ? 3.107   -28.69  12.508 1   56.48  ? 75  ASN A C   1 
ATOM   6965  O  O   . ASN E 1 93  ? 2.734   -29.251 13.553 1   54.96  ? 75  ASN A O   1 
ATOM   6966  C  CB  . ASN E 1 93  ? 4.138   -26.433 13.099 1   61.92  ? 75  ASN A CB  1 
ATOM   6967  C  CG  . ASN E 1 93  ? 5.425   -25.691 13.399 1   62.01  ? 75  ASN A CG  1 
ATOM   6968  O  OD1 . ASN E 1 93  ? 6.452   -26.303 13.679 1   62.06  ? 75  ASN A OD1 1 
ATOM   6969  N  ND2 . ASN E 1 93  ? 5.385   -24.371 13.349 1   63.46  ? 75  ASN A ND2 1 
ATOM   6970  N  N   . SER E 1 94  ? 2.476   -28.784 11.33  1   57.11  ? 76  SER A N   1 
ATOM   6971  C  CA  . SER E 1 94  ? 1.239   -29.578 11.086 1   58.49  ? 76  SER A CA  1 
ATOM   6972  C  C   . SER E 1 94  ? 1.502   -31.076 11.308 1   59.73  ? 76  SER A C   1 
ATOM   6973  O  O   . SER E 1 94  ? 0.617   -31.745 11.886 1   60.2   ? 76  SER A O   1 
ATOM   6974  C  CB  . SER E 1 94  ? 0.694   -29.326 9.707  1   58.06  ? 76  SER A CB  1 
ATOM   6975  O  OG  . SER E 1 94  ? 1.67    -29.624 8.723  1   59.03  ? 76  SER A OG  1 
ATOM   6976  N  N   . LYS E 1 95  ? 2.664   -31.576 10.862 1   57.21  ? 77  LYS A N   1 
ATOM   6977  C  CA  . LYS E 1 95  ? 3.115   -32.985 11.035 1   56.34  ? 77  LYS A CA  1 
ATOM   6978  C  C   . LYS E 1 95  ? 3.934   -33.141 12.331 1   54.54  ? 77  LYS A C   1 
ATOM   6979  O  O   . LYS E 1 95  ? 4.081   -34.291 12.786 1   55.36  ? 77  LYS A O   1 
ATOM   6980  C  CB  . LYS E 1 95  ? 3.937   -33.43  9.819  1   59.16  ? 77  LYS A CB  1 
ATOM   6981  C  CG  . LYS E 1 95  ? 3.244   -33.298 8.468  1   62.53  ? 77  LYS A CG  1 
ATOM   6982  C  CD  . LYS E 1 95  ? 4.068   -33.821 7.296  1   63.46  ? 77  LYS A CD  1 
ATOM   6983  C  CE  . LYS E 1 95  ? 3.226   -34.224 6.1    1   63.02  ? 77  LYS A CE  1 
ATOM   6984  N  NZ  . LYS E 1 95  ? 4.056   -34.724 4.983  0   62.4   ? 77  LYS A NZ  1 
ATOM   6985  N  N   . ASN E 1 96  ? 4.449   -32.041 12.901 1   52.18  ? 78  ASN A N   1 
ATOM   6986  C  CA  . ASN E 1 96  ? 5.35    -32.013 14.09  1   50.13  ? 78  ASN A CA  1 
ATOM   6987  C  C   . ASN E 1 96  ? 6.611   -32.822 13.765 1   49.58  ? 78  ASN A C   1 
ATOM   6988  O  O   . ASN E 1 96  ? 7.024   -33.654 14.591 1   51.44  ? 78  ASN A O   1 
ATOM   6989  C  CB  . ASN E 1 96  ? 4.652   -32.493 15.37  1   50.16  ? 78  ASN A CB  1 
ATOM   6990  C  CG  . ASN E 1 96  ? 5.441   -32.232 16.642 1   49.67  ? 78  ASN A CG  1 
ATOM   6991  O  OD1 . ASN E 1 96  ? 6.382   -31.442 16.652 1   52.01  ? 78  ASN A OD1 1 
ATOM   6992  N  ND2 . ASN E 1 96  ? 5.08    -32.898 17.726 1   47.49  ? 78  ASN A ND2 1 
ATOM   6993  N  N   . THR E 1 97  ? 7.199   -32.586 12.592 1   48.11  ? 79  THR A N   1 
ATOM   6994  C  CA  . THR E 1 97  ? 8.419   -33.289 12.127 1   49.14  ? 79  THR A CA  1 
ATOM   6995  C  C   . THR E 1 97  ? 9.508   -32.258 11.801 1   47.1   ? 79  THR A C   1 
ATOM   6996  O  O   . THR E 1 97  ? 9.174   -31.141 11.347 1   41.66  ? 79  THR A O   1 
ATOM   6997  C  CB  . THR E 1 97  ? 8.115   -34.255 10.97  1   50.7   ? 79  THR A CB  1 
ATOM   6998  O  OG1 . THR E 1 97  ? 7.995   -33.524 9.75   1   52.84  ? 79  THR A OG1 1 
ATOM   6999  C  CG2 . THR E 1 97  ? 6.855   -35.066 11.185 1   50.57  ? 79  THR A CG2 1 
ATOM   7000  N  N   . LEU E 1 98  ? 10.761  -32.644 12.053 1   46.42  ? 80  LEU A N   1 
ATOM   7001  C  CA  . LEU E 1 98  ? 11.988  -31.885 11.712 1   46.3   ? 80  LEU A CA  1 
ATOM   7002  C  C   . LEU E 1 98  ? 12.6    -32.531 10.467 1   44.7   ? 80  LEU A C   1 
ATOM   7003  O  O   . LEU E 1 98  ? 12.526  -33.767 10.357 1   45.09  ? 80  LEU A O   1 
ATOM   7004  C  CB  . LEU E 1 98  ? 12.944  -31.94  12.908 1   47.62  ? 80  LEU A CB  1 
ATOM   7005  C  CG  . LEU E 1 98  ? 13.836  -30.716 13.095 1   50.67  ? 80  LEU A CG  1 
ATOM   7006  C  CD1 . LEU E 1 98  ? 13.051  -29.573 13.717 1   50.87  ? 80  LEU A CD1 1 
ATOM   7007  C  CD2 . LEU E 1 98  ? 15.043  -31.06  13.953 1   53.94  ? 80  LEU A CD2 1 
ATOM   7008  N  N   . TYR E 1 99  ? 13.158  -31.726 9.562  1   43.92  ? 81  TYR A N   1 
ATOM   7009  C  CA  . TYR E 1 99  ? 13.828  -32.19  8.322  1   43.97  ? 81  TYR A CA  1 
ATOM   7010  C  C   . TYR E 1 99  ? 15.274  -31.699 8.306  1   43.87  ? 81  TYR A C   1 
ATOM   7011  O  O   . TYR E 1 99  ? 15.577  -30.663 8.908  1   44.67  ? 81  TYR A O   1 
ATOM   7012  C  CB  . TYR E 1 99  ? 13.088  -31.707 7.073  1   44.93  ? 81  TYR A CB  1 
ATOM   7013  C  CG  . TYR E 1 99  ? 11.641  -32.12  7.017  1   46.34  ? 81  TYR A CG  1 
ATOM   7014  C  CD1 . TYR E 1 99  ? 10.672  -31.372 7.659  1   47.05  ? 81  TYR A CD1 1 
ATOM   7015  C  CD2 . TYR E 1 99  ? 11.24   -33.274 6.359  1   47.32  ? 81  TYR A CD2 1 
ATOM   7016  C  CE1 . TYR E 1 99  ? 9.339   -31.741 7.631  1   48.15  ? 81  TYR A CE1 1 
ATOM   7017  C  CE2 . TYR E 1 99  ? 9.909   -33.659 6.323  1   48.19  ? 81  TYR A CE2 1 
ATOM   7018  C  CZ  . TYR E 1 99  ? 8.951   -32.885 6.958  1   48.7   ? 81  TYR A CZ  1 
ATOM   7019  O  OH  . TYR E 1 99  ? 7.631   -33.235 6.947  1   49.59  ? 81  TYR A OH  1 
ATOM   7020  N  N   . LEU E 1 100 ? 16.138  -32.458 7.639  1   44.9   ? 82  LEU A N   1 
ATOM   7021  C  CA  . LEU E 1 100 ? 17.472  -32.009 7.187  1   46.12  ? 82  LEU A CA  1 
ATOM   7022  C  C   . LEU E 1 100 ? 17.57   -32.332 5.694  1   48.81  ? 82  LEU A C   1 
ATOM   7023  O  O   . LEU E 1 100 ? 17.654  -33.526 5.348  1   48.7   ? 82  LEU A O   1 
ATOM   7024  C  CB  . LEU E 1 100 ? 18.554  -32.706 8.017  1   45.81  ? 82  LEU A CB  1 
ATOM   7025  C  CG  . LEU E 1 100 ? 19.988  -32.241 7.768  1   46.33  ? 82  LEU A CG  1 
ATOM   7026  C  CD1 . LEU E 1 100 ? 20.175  -30.785 8.163  1   46.3   ? 82  LEU A CD1 1 
ATOM   7027  C  CD2 . LEU E 1 100 ? 20.974  -33.116 8.524  1   47.44  ? 82  LEU A CD2 1 
ATOM   7028  N  N   . GLN E 1 101 ? 17.48   -31.306 4.846  1   51.47  ? 83  GLN A N   1 
ATOM   7029  C  CA  . GLN E 1 101 ? 17.765  -31.419 3.395  1   54.19  ? 83  GLN A CA  1 
ATOM   7030  C  C   . GLN E 1 101 ? 19.285  -31.429 3.24   1   54.57  ? 83  GLN A C   1 
ATOM   7031  O  O   . GLN E 1 101 ? 19.905  -30.479 3.717  1   55.42  ? 83  GLN A O   1 
ATOM   7032  C  CB  . GLN E 1 101 ? 17.123  -30.264 2.624  1   57.05  ? 83  GLN A CB  1 
ATOM   7033  C  CG  . GLN E 1 101 ? 17.289  -30.356 1.111  1   58.59  ? 83  GLN A CG  1 
ATOM   7034  C  CD  . GLN E 1 101 ? 16.617  -31.579 0.536  1   57.87  ? 83  GLN A CD  1 
ATOM   7035  O  OE1 . GLN E 1 101 ? 15.462  -31.865 0.84   1   57.9   ? 83  GLN A OE1 1 
ATOM   7036  N  NE2 . GLN E 1 101 ? 17.34   -32.319 -0.291 1   58.93  ? 83  GLN A NE2 1 
ATOM   7037  N  N   . MET E 1 102 ? 19.842  -32.479 2.634  1   56.29  ? 84  MET A N   1 
ATOM   7038  C  CA  . MET E 1 102 ? 21.303  -32.671 2.431  1   59.07  ? 84  MET A CA  1 
ATOM   7039  C  C   . MET E 1 102 ? 21.587  -32.691 0.923  1   58.09  ? 84  MET A C   1 
ATOM   7040  O  O   . MET E 1 102 ? 20.955  -33.503 0.239  1   54.97  ? 84  MET A O   1 
ATOM   7041  C  CB  . MET E 1 102 ? 21.76   -33.983 3.078  1   61.28  ? 84  MET A CB  1 
ATOM   7042  C  CG  . MET E 1 102 ? 21.648  -33.974 4.599  1   63.17  ? 84  MET A CG  1 
ATOM   7043  S  SD  . MET E 1 102 ? 21.574  -35.621 5.364  1   65.69  ? 84  MET A SD  1 
ATOM   7044  C  CE  . MET E 1 102 ? 23.14   -36.318 4.849  1   67.56  ? 84  MET A CE  1 
ATOM   7045  N  N   . ASN E 1 103 ? 22.466  -31.803 0.436  1   59.17  ? 85  ASN A N   1 
ATOM   7046  C  CA  . ASN E 1 103 ? 22.853  -31.665 -0.999 1   59.65  ? 85  ASN A CA  1 
ATOM   7047  C  C   . ASN E 1 103 ? 24.373  -31.812 -1.145 1   58.72  ? 85  ASN A C   1 
ATOM   7048  O  O   . ASN E 1 103 ? 25.085  -31.678 -0.129 1   57.67  ? 85  ASN A O   1 
ATOM   7049  C  CB  . ASN E 1 103 ? 22.396  -30.329 -1.592 1   57.87  ? 85  ASN A CB  1 
ATOM   7050  C  CG  . ASN E 1 103 ? 20.892  -30.143 -1.579 1   58.57  ? 85  ASN A CG  1 
ATOM   7051  O  OD1 . ASN E 1 103 ? 20.136  -31.105 -1.696 1   60.48  ? 85  ASN A OD1 1 
ATOM   7052  N  ND2 . ASN E 1 103 ? 20.441  -28.905 -1.45  1   58.99  ? 85  ASN A ND2 1 
ATOM   7053  N  N   . SER E 1 104 ? 24.84   -32.089 -2.367 1   60.44  ? 86  SER A N   1 
ATOM   7054  C  CA  . SER E 1 104 ? 26.276  -32.193 -2.744 1   64.41  ? 86  SER A CA  1 
ATOM   7055  C  C   . SER E 1 104 ? 27.021  -33.07  -1.726 1   64.77  ? 86  SER A C   1 
ATOM   7056  O  O   . SER E 1 104 ? 28.054  -32.623 -1.183 1   68.56  ? 86  SER A O   1 
ATOM   7057  C  CB  . SER E 1 104 ? 26.896  -30.819 -2.868 1   65.84  ? 86  SER A CB  1 
ATOM   7058  O  OG  . SER E 1 104 ? 26.098  -29.967 -3.678 1   69.53  ? 86  SER A OG  1 
ATOM   7059  N  N   . LEU E 1 105 ? 26.499  -34.272 -1.467 1   62.07  ? 87  LEU A N   1 
ATOM   7060  C  CA  . LEU E 1 105 ? 26.976  -35.157 -0.369 1   60.74  ? 87  LEU A CA  1 
ATOM   7061  C  C   . LEU E 1 105 ? 28.301  -35.821 -0.759 1   61.27  ? 87  LEU A C   1 
ATOM   7062  O  O   . LEU E 1 105 ? 28.51   -36.083 -1.957 1   59.82  ? 87  LEU A O   1 
ATOM   7063  C  CB  . LEU E 1 105 ? 25.893  -36.181 -0.022 1   60.32  ? 87  LEU A CB  1 
ATOM   7064  C  CG  . LEU E 1 105 ? 24.813  -35.654 0.92   1   62.01  ? 87  LEU A CG  1 
ATOM   7065  C  CD1 . LEU E 1 105 ? 23.568  -36.525 0.879  1   62.97  ? 87  LEU A CD1 1 
ATOM   7066  C  CD2 . LEU E 1 105 ? 25.347  -35.55  2.342  1   62.78  ? 87  LEU A CD2 1 
ATOM   7067  N  N   . ARG E 1 106 ? 29.158  -36.051 0.24   1   63.28  ? 88  ARG A N   1 
ATOM   7068  C  CA  . ARG E 1 106 ? 30.557  -36.535 0.1    1   67.74  ? 88  ARG A CA  1 
ATOM   7069  C  C   . ARG E 1 106 ? 30.767  -37.721 1.045  1   68.15  ? 88  ARG A C   1 
ATOM   7070  O  O   . ARG E 1 106 ? 29.983  -37.848 2.002  1   69.03  ? 88  ARG A O   1 
ATOM   7071  C  CB  . ARG E 1 106 ? 31.557  -35.435 0.479  1   73.38  ? 88  ARG A CB  1 
ATOM   7072  C  CG  . ARG E 1 106 ? 31.341  -34.086 -0.195 1   76.18  ? 88  ARG A CG  1 
ATOM   7073  C  CD  . ARG E 1 106 ? 31.948  -32.948 0.613  1   79.12  ? 88  ARG A CD  1 
ATOM   7074  N  NE  . ARG E 1 106 ? 31.563  -31.631 0.11   1   80.73  ? 88  ARG A NE  1 
ATOM   7075  C  CZ  . ARG E 1 106 ? 31.828  -30.465 0.705  1   81.32  ? 88  ARG A CZ  1 
ATOM   7076  N  NH1 . ARG E 1 106 ? 32.491  -30.42  1.851  1   81.6   ? 88  ARG A NH1 1 
ATOM   7077  N  NH2 . ARG E 1 106 ? 31.424  -29.336 0.146  1   84.02  ? 88  ARG A NH2 1 
ATOM   7078  N  N   . ALA E 1 107 ? 31.812  -38.523 0.813  1   68.95  ? 89  ALA A N   1 
ATOM   7079  C  CA  . ALA E 1 107 ? 32.249  -39.642 1.688  1   69.24  ? 89  ALA A CA  1 
ATOM   7080  C  C   . ALA E 1 107 ? 32.25   -39.2   3.162  1   69.27  ? 89  ALA A C   1 
ATOM   7081  O  O   . ALA E 1 107 ? 31.766  -39.975 4.013  1   70.3   ? 89  ALA A O   1 
ATOM   7082  C  CB  . ALA E 1 107 ? 33.614  -40.133 1.263  1   67.62  ? 89  ALA A CB  1 
ATOM   7083  N  N   . GLU E 1 108 ? 32.717  -37.976 3.434  1   67.56  ? 90  GLU A N   1 
ATOM   7084  C  CA  . GLU E 1 108 ? 32.897  -37.398 4.796  1   68.67  ? 90  GLU A CA  1 
ATOM   7085  C  C   . GLU E 1 108 ? 31.543  -37.175 5.492  1   63.99  ? 90  GLU A C   1 
ATOM   7086  O  O   . GLU E 1 108 ? 31.562  -36.995 6.726  1   63.65  ? 90  GLU A O   1 
ATOM   7087  C  CB  . GLU E 1 108 ? 33.668  -36.075 4.729  1   72.18  ? 90  GLU A CB  1 
ATOM   7088  C  CG  . GLU E 1 108 ? 35.087  -36.215 4.19   1   77.9   ? 90  GLU A CG  1 
ATOM   7089  C  CD  . GLU E 1 108 ? 35.23   -36.248 2.674  1   78.64  ? 90  GLU A CD  1 
ATOM   7090  O  OE1 . GLU E 1 108 ? 36.025  -37.07  2.175  1   78.08  ? 90  GLU A OE1 1 
ATOM   7091  O  OE2 . GLU E 1 108 ? 34.543  -35.458 1.993  1   78.51  ? 90  GLU A OE2 1 
ATOM   7092  N  N   . ASP E 1 109 ? 30.426  -37.165 4.751  1   56.67  ? 91  ASP A N   1 
ATOM   7093  C  CA  . ASP E 1 109 ? 29.051  -37.003 5.301  1   55.5   ? 91  ASP A CA  1 
ATOM   7094  C  C   . ASP E 1 109 ? 28.437  -38.357 5.698  1   51.49  ? 91  ASP A C   1 
ATOM   7095  O  O   . ASP E 1 109 ? 27.337  -38.337 6.293  1   47.8   ? 91  ASP A O   1 
ATOM   7096  C  CB  . ASP E 1 109 ? 28.147  -36.271 4.307  1   58.3   ? 91  ASP A CB  1 
ATOM   7097  C  CG  . ASP E 1 109 ? 28.596  -34.85  4.024  1   61.22  ? 91  ASP A CG  1 
ATOM   7098  O  OD1 . ASP E 1 109 ? 28.647  -34.056 4.984  1   61.83  ? 91  ASP A OD1 1 
ATOM   7099  O  OD2 . ASP E 1 109 ? 28.892  -34.548 2.848  1   63.18  ? 91  ASP A OD2 1 
ATOM   7100  N  N   . THR E 1 110 ? 29.081  -39.486 5.372  1   47.31  ? 92  THR A N   1 
ATOM   7101  C  CA  . THR E 1 110 ? 28.68   -40.832 5.857  1   46.39  ? 92  THR A CA  1 
ATOM   7102  C  C   . THR E 1 110 ? 28.638  -40.767 7.384  1   46.45  ? 92  THR A C   1 
ATOM   7103  O  O   . THR E 1 110 ? 29.687  -40.447 7.965  1   48.91  ? 92  THR A O   1 
ATOM   7104  C  CB  . THR E 1 110 ? 29.635  -41.937 5.383  1   46.73  ? 92  THR A CB  1 
ATOM   7105  O  OG1 . THR E 1 110 ? 29.643  -41.985 3.954  1   48.48  ? 92  THR A OG1 1 
ATOM   7106  C  CG2 . THR E 1 110 ? 29.265  -43.303 5.92   1   45.35  ? 92  THR A CG2 1 
ATOM   7107  N  N   . ALA E 1 111 ? 27.476  -41.02  7.997  1   46.08  ? 93  ALA A N   1 
ATOM   7108  C  CA  . ALA E 1 111 ? 27.269  -40.934 9.465  1   45.63  ? 93  ALA A CA  1 
ATOM   7109  C  C   . ALA E 1 111 ? 25.868  -41.4   9.864  1   42.87  ? 93  ALA A C   1 
ATOM   7110  O  O   . ALA E 1 111 ? 24.967  -41.399 9.008  1   42.6   ? 93  ALA A O   1 
ATOM   7111  C  CB  . ALA E 1 111 ? 27.489  -39.516 9.946  1   45.85  ? 93  ALA A CB  1 
ATOM   7112  N  N   . VAL E 1 112 ? 25.71   -41.771 11.136 1   39.89  ? 94  VAL A N   1 
ATOM   7113  C  CA  . VAL E 1 112 ? 24.39   -41.813 11.824 1   40.54  ? 94  VAL A CA  1 
ATOM   7114  C  C   . VAL E 1 112 ? 24.01   -40.358 12.119 1   40.56  ? 94  VAL A C   1 
ATOM   7115  O  O   . VAL E 1 112 ? 24.831  -39.649 12.739 1   40.23  ? 94  VAL A O   1 
ATOM   7116  C  CB  . VAL E 1 112 ? 24.408  -42.678 13.103 1   39.95  ? 94  VAL A CB  1 
ATOM   7117  C  CG1 . VAL E 1 112 ? 23.095  -42.599 13.869 1   39.33  ? 94  VAL A CG1 1 
ATOM   7118  C  CG2 . VAL E 1 112 ? 24.741  -44.129 12.791 1   39.69  ? 94  VAL A CG2 1 
ATOM   7119  N  N   . TYR E 1 113 ? 22.826  -39.944 11.664 1   38.27  ? 95  TYR A N   1 
ATOM   7120  C  CA  . TYR E 1 113 ? 22.227  -38.61  11.9   1   38.35  ? 95  TYR A CA  1 
ATOM   7121  C  C   . TYR E 1 113 ? 21.152  -38.753 12.982 1   38.05  ? 95  TYR A C   1 
ATOM   7122  O  O   . TYR E 1 113 ? 20.146  -39.46  12.754 1   38.45  ? 95  TYR A O   1 
ATOM   7123  C  CB  . TYR E 1 113 ? 21.696  -38.033 10.585 1   38.6   ? 95  TYR A CB  1 
ATOM   7124  C  CG  . TYR E 1 113 ? 22.773  -37.513 9.668  1   37.89  ? 95  TYR A CG  1 
ATOM   7125  C  CD1 . TYR E 1 113 ? 23.542  -38.375 8.903  1   37.85  ? 95  TYR A CD1 1 
ATOM   7126  C  CD2 . TYR E 1 113 ? 23.037  -36.155 9.572  1   38.72  ? 95  TYR A CD2 1 
ATOM   7127  C  CE1 . TYR E 1 113 ? 24.542  -37.906 8.064  1   37.84  ? 95  TYR A CE1 1 
ATOM   7128  C  CE2 . TYR E 1 113 ? 24.032  -35.668 8.737  1   38.13  ? 95  TYR A CE2 1 
ATOM   7129  C  CZ  . TYR E 1 113 ? 24.79   -36.547 7.983  1   38.17  ? 95  TYR A CZ  1 
ATOM   7130  O  OH  . TYR E 1 113 ? 25.77   -36.076 7.159  1   38.67  ? 95  TYR A OH  1 
ATOM   7131  N  N   . TYR E 1 114 ? 21.39   -38.123 14.135 1   37.32  ? 96  TYR A N   1 
ATOM   7132  C  CA  . TYR E 1 114 ? 20.437  -37.996 15.265 1   39.01  ? 96  TYR A CA  1 
ATOM   7133  C  C   . TYR E 1 114 ? 19.72   -36.648 15.166 1   41.58  ? 96  TYR A C   1 
ATOM   7134  O  O   . TYR E 1 114 ? 20.399  -35.645 14.888 1   42.82  ? 96  TYR A O   1 
ATOM   7135  C  CB  . TYR E 1 114 ? 21.168  -38.075 16.609 1   38.78  ? 96  TYR A CB  1 
ATOM   7136  C  CG  . TYR E 1 114 ? 21.924  -39.356 16.849 1   37.04  ? 96  TYR A CG  1 
ATOM   7137  C  CD1 . TYR E 1 114 ? 21.275  -40.498 17.298 1   36.67  ? 96  TYR A CD1 1 
ATOM   7138  C  CD2 . TYR E 1 114 ? 23.288  -39.431 16.622 1   36.4   ? 96  TYR A CD2 1 
ATOM   7139  C  CE1 . TYR E 1 114 ? 21.96   -41.684 17.51  1   36.87  ? 96  TYR A CE1 1 
ATOM   7140  C  CE2 . TYR E 1 114 ? 23.988  -40.609 16.83  1   37.44  ? 96  TYR A CE2 1 
ATOM   7141  C  CZ  . TYR E 1 114 ? 23.324  -41.736 17.281 1   37.02  ? 96  TYR A CZ  1 
ATOM   7142  O  OH  . TYR E 1 114 ? 24.019  -42.889 17.484 1   39.26  ? 96  TYR A OH  1 
ATOM   7143  N  N   . CYS E 1 115 ? 18.405  -36.62  15.383 1   43.59  ? 97  CYS A N   1 
ATOM   7144  C  CA  . CYS E 1 115 ? 17.671  -35.388 15.775 1   48.01  ? 97  CYS A CA  1 
ATOM   7145  C  C   . CYS E 1 115 ? 17.567  -35.377 17.304 1   46.07  ? 97  CYS A C   1 
ATOM   7146  O  O   . CYS E 1 115 ? 17.414  -36.465 17.904 1   43.89  ? 97  CYS A O   1 
ATOM   7147  C  CB  . CYS E 1 115 ? 16.31   -35.255 15.096 1   53.15  ? 97  CYS A CB  1 
ATOM   7148  S  SG  . CYS E 1 115 ? 15.152  -36.591 15.483 1   61.44  ? 97  CYS A SG  1 
ATOM   7149  N  N   . ALA E 1 116 ? 17.698  -34.197 17.91  1   44.36  ? 98  ALA A N   1 
ATOM   7150  C  CA  . ALA E 1 116 ? 17.749  -34.022 19.378 1   43.8   ? 98  ALA A CA  1 
ATOM   7151  C  C   . ALA E 1 116 ? 16.945  -32.788 19.78  1   43.23  ? 98  ALA A C   1 
ATOM   7152  O  O   . ALA E 1 116 ? 17.008  -31.778 19.059 1   43.21  ? 98  ALA A O   1 
ATOM   7153  C  CB  . ALA E 1 116 ? 19.18   -33.917 19.837 1   43.91  ? 98  ALA A CB  1 
ATOM   7154  N  N   . LYS E 1 117 ? 16.215  -32.898 20.89  1   43.96  ? 99  LYS A N   1 
ATOM   7155  C  CA  . LYS E 1 117 ? 15.465  -31.789 21.53  1   44.37  ? 99  LYS A CA  1 
ATOM   7156  C  C   . LYS E 1 117 ? 16.384  -31.134 22.563 1   42.96  ? 99  LYS A C   1 
ATOM   7157  O  O   . LYS E 1 117 ? 16.867  -31.853 23.458 1   41.9   ? 99  LYS A O   1 
ATOM   7158  C  CB  . LYS E 1 117 ? 14.191  -32.327 22.186 1   46.58  ? 99  LYS A CB  1 
ATOM   7159  C  CG  . LYS E 1 117 ? 13.341  -31.294 22.911 1   48.91  ? 99  LYS A CG  1 
ATOM   7160  C  CD  . LYS E 1 117 ? 12.32   -31.904 23.841 1   52.04  ? 99  LYS A CD  1 
ATOM   7161  C  CE  . LYS E 1 117 ? 11.823  -30.919 24.876 1   53.52  ? 99  LYS A CE  1 
ATOM   7162  N  NZ  . LYS E 1 117 ? 10.482  -31.299 25.376 1   57.67  ? 99  LYS A NZ  1 
ATOM   7163  N  N   . VAL E 1 118 ? 16.606  -29.823 22.45  1   42.75  ? 100 VAL A N   1 
ATOM   7164  C  CA  . VAL E 1 118 ? 17.41   -29.046 23.438 1   41.61  ? 100 VAL A CA  1 
ATOM   7165  C  C   . VAL E 1 118 ? 16.489  -28.642 24.592 1   41.61  ? 100 VAL A C   1 
ATOM   7166  O  O   . VAL E 1 118 ? 15.366  -28.198 24.31  1   42.51  ? 100 VAL A O   1 
ATOM   7167  C  CB  . VAL E 1 118 ? 18.081  -27.818 22.8   1   39.98  ? 100 VAL A CB  1 
ATOM   7168  C  CG1 . VAL E 1 118 ? 18.903  -27.054 23.819 1   40.64  ? 100 VAL A CG1 1 
ATOM   7169  C  CG2 . VAL E 1 118 ? 18.939  -28.19  21.602 1   40.13  ? 100 VAL A CG2 1 
ATOM   7170  N  N   . ASP E 1 119 ? 16.964  -28.776 25.834 1   42.89  ? 101 ASP A N   1 
ATOM   7171  C  CA  . ASP E 1 119 ? 16.235  -28.353 27.06  1   45.42  ? 101 ASP A CA  1 
ATOM   7172  C  C   . ASP E 1 119 ? 16.602  -26.889 27.359 1   46.15  ? 101 ASP A C   1 
ATOM   7173  O  O   . ASP E 1 119 ? 16.484  -26.055 26.44  1   45.57  ? 101 ASP A O   1 
ATOM   7174  C  CB  . ASP E 1 119 ? 16.506  -29.321 28.218 1   47.91  ? 101 ASP A CB  1 
ATOM   7175  C  CG  . ASP E 1 119 ? 16.095  -30.764 27.977 1   48.64  ? 101 ASP A CG  1 
ATOM   7176  O  OD1 . ASP E 1 119 ? 15.316  -31.019 27.03  1   49.89  ? 101 ASP A OD1 1 
ATOM   7177  O  OD2 . ASP E 1 119 ? 16.554  -31.626 28.758 1   49.4   ? 101 ASP A OD2 1 
ATOM   7178  N  N   . SER E 1 120 ? 17.049  -26.58  28.581 1   47.57  ? 102 SER A N   1 
ATOM   7179  C  CA  . SER E 1 120 ? 17.098  -25.203 29.135 1   48.89  ? 102 SER A CA  1 
ATOM   7180  C  C   . SER E 1 120 ? 18.451  -24.536 28.863 1   48.23  ? 102 SER A C   1 
ATOM   7181  O  O   . SER E 1 120 ? 18.479  -23.287 28.832 1   50.94  ? 102 SER A O   1 
ATOM   7182  C  CB  . SER E 1 120 ? 16.795  -25.217 30.611 1   50.95  ? 102 SER A CB  1 
ATOM   7183  O  OG  . SER E 1 120 ? 17.706  -26.062 31.299 1   56.43  ? 102 SER A OG  1 
ATOM   7184  N  N   . ALA E 1 121 ? 19.512  -25.326 28.648 1   45.06  ? 103 ALA A N   1 
ATOM   7185  C  CA  . ALA E 1 121 ? 20.923  -24.887 28.751 1   42.87  ? 103 ALA A CA  1 
ATOM   7186  C  C   . ALA E 1 121 ? 21.77   -25.395 27.577 1   40.53  ? 103 ALA A C   1 
ATOM   7187  O  O   . ALA E 1 121 ? 22.935  -25.748 27.811 1   43.08  ? 103 ALA A O   1 
ATOM   7188  C  CB  . ALA E 1 121 ? 21.466  -25.364 30.073 1   42.41  ? 103 ALA A CB  1 
ATOM   7189  N  N   . TYR E 1 122 ? 21.237  -25.379 26.355 1   39.89  ? 104 TYR A N   1 
ATOM   7190  C  CA  . TYR E 1 122 ? 21.943  -25.823 25.121 1   41.2   ? 104 TYR A CA  1 
ATOM   7191  C  C   . TYR E 1 122 ? 22.432  -27.265 25.317 1   41.48  ? 104 TYR A C   1 
ATOM   7192  O  O   . TYR E 1 122 ? 23.567  -27.603 24.926 1   45.38  ? 104 TYR A O   1 
ATOM   7193  C  CB  . TYR E 1 122 ? 23.068  -24.846 24.772 1   41.35  ? 104 TYR A CB  1 
ATOM   7194  C  CG  . TYR E 1 122 ? 22.614  -23.427 24.537 1   42.41  ? 104 TYR A CG  1 
ATOM   7195  C  CD1 . TYR E 1 122 ? 22.184  -23.015 23.285 1   43.49  ? 104 TYR A CD1 1 
ATOM   7196  C  CD2 . TYR E 1 122 ? 22.616  -22.488 25.559 1   42.45  ? 104 TYR A CD2 1 
ATOM   7197  C  CE1 . TYR E 1 122 ? 21.768  -21.712 23.057 1   43.59  ? 104 TYR A CE1 1 
ATOM   7198  C  CE2 . TYR E 1 122 ? 22.204  -21.181 25.348 1   42.02  ? 104 TYR A CE2 1 
ATOM   7199  C  CZ  . TYR E 1 122 ? 21.779  -20.789 24.089 1   42.71  ? 104 TYR A CZ  1 
ATOM   7200  O  OH  . TYR E 1 122 ? 21.373  -19.505 23.859 1   43.47  ? 104 TYR A OH  1 
ATOM   7201  N  N   . ASP E 1 123 ? 21.575  -28.086 25.928 1   41.35  ? 105 ASP A N   1 
ATOM   7202  C  CA  . ASP E 1 123 ? 21.842  -29.489 26.33  1   41.26  ? 105 ASP A CA  1 
ATOM   7203  C  C   . ASP E 1 123 ? 20.851  -30.388 25.584 1   41.54  ? 105 ASP A C   1 
ATOM   7204  O  O   . ASP E 1 123 ? 19.635  -30.085 25.617 1   42.29  ? 105 ASP A O   1 
ATOM   7205  C  CB  . ASP E 1 123 ? 21.729  -29.662 27.848 1   42.18  ? 105 ASP A CB  1 
ATOM   7206  C  CG  . ASP E 1 123 ? 20.419  -29.162 28.436 1   43.72  ? 105 ASP A CG  1 
ATOM   7207  O  OD1 . ASP E 1 123 ? 19.907  -28.148 27.935 1   42.91  ? 105 ASP A OD1 1 
ATOM   7208  O  OD2 . ASP E 1 123 ? 19.91   -29.803 29.376 1   48.58  ? 105 ASP A OD2 1 
ATOM   7209  N  N   . PHE E 1 124 ? 21.352  -31.448 24.942 1   39.18  ? 106 PHE A N   1 
ATOM   7210  C  CA  . PHE E 1 124 ? 20.546  -32.431 24.173 1   36.9   ? 106 PHE A CA  1 
ATOM   7211  C  C   . PHE E 1 124 ? 19.885  -33.403 25.157 1   34.6   ? 106 PHE A C   1 
ATOM   7212  O  O   . PHE E 1 124 ? 20.485  -34.421 25.487 1   32.49  ? 106 PHE A O   1 
ATOM   7213  C  CB  . PHE E 1 124 ? 21.427  -33.122 23.132 1   37.42  ? 106 PHE A CB  1 
ATOM   7214  C  CG  . PHE E 1 124 ? 22.099  -32.163 22.187 1   37.5   ? 106 PHE A CG  1 
ATOM   7215  C  CD1 . PHE E 1 124 ? 21.346  -31.388 21.319 1   38.41  ? 106 PHE A CD1 1 
ATOM   7216  C  CD2 . PHE E 1 124 ? 23.478  -32.02  22.176 1   39.73  ? 106 PHE A CD2 1 
ATOM   7217  C  CE1 . PHE E 1 124 ? 21.957  -30.494 20.453 1   39.39  ? 106 PHE A CE1 1 
ATOM   7218  C  CE2 . PHE E 1 124 ? 24.09   -31.133 21.302 1   40.74  ? 106 PHE A CE2 1 
ATOM   7219  C  CZ  . PHE E 1 124 ? 23.328  -30.371 20.441 1   40.03  ? 106 PHE A CZ  1 
ATOM   7220  N  N   . GLY E 1 125 ? 18.684  -33.067 25.633 1   34.61  ? 107 GLY A N   1 
ATOM   7221  C  CA  . GLY E 1 125 ? 17.959  -33.829 26.668 1   35.11  ? 107 GLY A CA  1 
ATOM   7222  C  C   . GLY E 1 125 ? 17.358  -35.118 26.133 1   35.63  ? 107 GLY A C   1 
ATOM   7223  O  O   . GLY E 1 125 ? 17.345  -36.113 26.879 1   36.09  ? 107 GLY A O   1 
ATOM   7224  N  N   . SER E 1 126 ? 16.837  -35.09  24.904 1   35.39  ? 108 SER A N   1 
ATOM   7225  C  CA  . SER E 1 126 ? 16.122  -36.215 24.252 1   35.54  ? 108 SER A CA  1 
ATOM   7226  C  C   . SER E 1 126 ? 16.706  -36.429 22.855 1   36.58  ? 108 SER A C   1 
ATOM   7227  O  O   . SER E 1 126 ? 16.797  -35.438 22.095 1   35.89  ? 108 SER A O   1 
ATOM   7228  C  CB  . SER E 1 126 ? 14.642  -35.956 24.203 1   36.61  ? 108 SER A CB  1 
ATOM   7229  O  OG  . SER E 1 126 ? 14.189  -35.4   25.431 1   38.43  ? 108 SER A OG  1 
ATOM   7230  N  N   . TRP E 1 127 ? 17.118  -37.668 22.565 1   36.44  ? 109 TRP A N   1 
ATOM   7231  C  CA  . TRP E 1 127 ? 17.744  -38.1   21.29  1   36.29  ? 109 TRP A CA  1 
ATOM   7232  C  C   . TRP E 1 127 ? 16.86   -39.155 20.626 1   36.83  ? 109 TRP A C   1 
ATOM   7233  O  O   . TRP E 1 127 ? 16.315  -40.005 21.35  1   38.04  ? 109 TRP A O   1 
ATOM   7234  C  CB  . TRP E 1 127 ? 19.135  -38.686 21.545 1   35.93  ? 109 TRP A CB  1 
ATOM   7235  C  CG  . TRP E 1 127 ? 20.148  -37.748 22.124 1   35.15  ? 109 TRP A CG  1 
ATOM   7236  C  CD1 . TRP E 1 127 ? 20.173  -37.226 23.384 1   34.57  ? 109 TRP A CD1 1 
ATOM   7237  C  CD2 . TRP E 1 127 ? 21.343  -37.282 21.474 1   34.27  ? 109 TRP A CD2 1 
ATOM   7238  N  NE1 . TRP E 1 127 ? 21.288  -36.451 23.552 1   33.93  ? 109 TRP A NE1 1 
ATOM   7239  C  CE2 . TRP E 1 127 ? 22.024  -36.466 22.399 1   33.9   ? 109 TRP A CE2 1 
ATOM   7240  C  CE3 . TRP E 1 127 ? 21.899  -37.469 20.204 1   34.86  ? 109 TRP A CE3 1 
ATOM   7241  C  CZ2 . TRP E 1 127 ? 23.228  -35.838 22.091 1   35.16  ? 109 TRP A CZ2 1 
ATOM   7242  C  CZ3 . TRP E 1 127 ? 23.089  -36.848 19.899 1   34.86  ? 109 TRP A CZ3 1 
ATOM   7243  C  CH2 . TRP E 1 127 ? 23.743  -36.043 20.831 1   35.22  ? 109 TRP A CH2 1 
ATOM   7244  N  N   . GLY E 1 128 ? 16.776  -39.137 19.296 1   38.15  ? 110 GLY A N   1 
ATOM   7245  C  CA  . GLY E 1 128 ? 16.233  -40.263 18.517 1   38.89  ? 110 GLY A CA  1 
ATOM   7246  C  C   . GLY E 1 128 ? 17.212  -41.425 18.469 1   41.02  ? 110 GLY A C   1 
ATOM   7247  O  O   . GLY E 1 128 ? 18.276  -41.339 19.117 1   41.87  ? 110 GLY A O   1 
ATOM   7248  N  N   . GLN E 1 129 ? 16.848  -42.494 17.755 1   45.18  ? 111 GLN A N   1 
ATOM   7249  C  CA  . GLN E 1 129 ? 17.635  -43.758 17.645 1   46.26  ? 111 GLN A CA  1 
ATOM   7250  C  C   . GLN E 1 129 ? 18.712  -43.597 16.562 1   45.07  ? 111 GLN A C   1 
ATOM   7251  O  O   . GLN E 1 129 ? 19.709  -44.345 16.618 1   47.72  ? 111 GLN A O   1 
ATOM   7252  C  CB  . GLN E 1 129 ? 16.717  -44.968 17.408 1   47.16  ? 111 GLN A CB  1 
ATOM   7253  C  CG  . GLN E 1 129 ? 15.958  -44.968 16.083 1   49.35  ? 111 GLN A CG  1 
ATOM   7254  C  CD  . GLN E 1 129 ? 15.077  -46.15  15.874 0   47.74  ? 111 GLN A CD  1 
ATOM   7255  O  OE1 . GLN E 1 129 ? 14.783  -46.901 16.802 0   47.86  ? 111 GLN A OE1 1 
ATOM   7256  N  NE2 . GLN E 1 129 ? 14.638  -46.347 14.64  0   47.79  ? 111 GLN A NE2 1 
ATOM   7257  N  N   . GLY E 1 130 ? 18.512  -42.666 15.622 1   43.81  ? 112 GLY A N   1 
ATOM   7258  C  CA  . GLY E 1 130 ? 19.491  -42.275 14.587 1   43.36  ? 112 GLY A CA  1 
ATOM   7259  C  C   . GLY E 1 130 ? 19.196  -42.947 13.254 1   41.67  ? 112 GLY A C   1 
ATOM   7260  O  O   . GLY E 1 130 ? 18.577  -44.031 13.26  1   42.17  ? 112 GLY A O   1 
ATOM   7261  N  N   . THR E 1 131 ? 19.619  -42.33  12.148 1   39.94  ? 113 THR A N   1 
ATOM   7262  C  CA  . THR E 1 131 ? 19.483  -42.889 10.776 1   38.53  ? 113 THR A CA  1 
ATOM   7263  C  C   . THR E 1 131 ? 20.83   -42.773 10.045 1   37.35  ? 113 THR A C   1 
ATOM   7264  O  O   . THR E 1 131 ? 21.405  -41.669 10.027 1   37.22  ? 113 THR A O   1 
ATOM   7265  C  CB  . THR E 1 131 ? 18.274  -42.268 10.064 1   38.46  ? 113 THR A CB  1 
ATOM   7266  O  OG1 . THR E 1 131 ? 18.034  -43.032 8.883  1   39.24  ? 113 THR A OG1 1 
ATOM   7267  C  CG2 . THR E 1 131 ? 18.441  -40.804 9.719  1   38.72  ? 113 THR A CG2 1 
ATOM   7268  N  N   . LEU E 1 132 ? 21.313  -43.884 9.478  1   37.03  ? 114 LEU A N   1 
ATOM   7269  C  CA  . LEU E 1 132 ? 22.643  -44.003 8.825  1   37.55  ? 114 LEU A CA  1 
ATOM   7270  C  C   . LEU E 1 132 ? 22.509  -43.596 7.353  1   38.16  ? 114 LEU A C   1 
ATOM   7271  O  O   . LEU E 1 132 ? 21.782  -44.275 6.607  1   37.88  ? 114 LEU A O   1 
ATOM   7272  C  CB  . LEU E 1 132 ? 23.165  -45.437 8.965  1   37.77  ? 114 LEU A CB  1 
ATOM   7273  C  CG  . LEU E 1 132 ? 24.548  -45.713 8.369  1   38.75  ? 114 LEU A CG  1 
ATOM   7274  C  CD1 . LEU E 1 132 ? 25.621  -44.867 9.034  1   39.72  ? 114 LEU A CD1 1 
ATOM   7275  C  CD2 . LEU E 1 132 ? 24.905  -47.184 8.488  1   39.11  ? 114 LEU A CD2 1 
ATOM   7276  N  N   . VAL E 1 133 ? 23.162  -42.499 6.976  1   39.93  ? 115 VAL A N   1 
ATOM   7277  C  CA  . VAL E 1 133 ? 23.339  -42.064 5.563  1   42.05  ? 115 VAL A CA  1 
ATOM   7278  C  C   . VAL E 1 133 ? 24.687  -42.615 5.099  1   44.2   ? 115 VAL A C   1 
ATOM   7279  O  O   . VAL E 1 133 ? 25.688  -42.361 5.795  1   46.59  ? 115 VAL A O   1 
ATOM   7280  C  CB  . VAL E 1 133 ? 23.276  -40.532 5.436  1   42.99  ? 115 VAL A CB  1 
ATOM   7281  C  CG1 . VAL E 1 133 ? 23.394  -40.088 3.987  1   44.89  ? 115 VAL A CG1 1 
ATOM   7282  C  CG2 . VAL E 1 133 ? 22.013  -39.969 6.072  1   43.31  ? 115 VAL A CG2 1 
ATOM   7283  N  N   . THR E 1 134 ? 24.703  -43.37  3.999  1   43.89  ? 116 THR A N   1 
ATOM   7284  C  CA  . THR E 1 134 ? 25.935  -43.926 3.383  1   45.16  ? 116 THR A CA  1 
ATOM   7285  C  C   . THR E 1 134 ? 26.141  -43.228 2.037  1   46.61  ? 116 THR A C   1 
ATOM   7286  O  O   . THR E 1 134 ? 25.268  -43.376 1.165  1   46     ? 116 THR A O   1 
ATOM   7287  C  CB  . THR E 1 134 ? 25.855  -45.454 3.269  1   45.76  ? 116 THR A CB  1 
ATOM   7288  O  OG1 . THR E 1 134 ? 25.482  -45.971 4.547  1   45.34  ? 116 THR A OG1 1 
ATOM   7289  C  CG2 . THR E 1 134 ? 27.16   -46.082 2.829  1   45.86  ? 116 THR A CG2 1 
ATOM   7290  N  N   . VAL E 1 135 ? 27.223  -42.453 1.905  1   48.52  ? 117 VAL A N   1 
ATOM   7291  C  CA  . VAL E 1 135 ? 27.628  -41.788 0.632  1   50.9   ? 117 VAL A CA  1 
ATOM   7292  C  C   . VAL E 1 135 ? 28.691  -42.672 -0.025 1   52.79  ? 117 VAL A C   1 
ATOM   7293  O  O   . VAL E 1 135 ? 29.775  -42.823 0.569  1   54.86  ? 117 VAL A O   1 
ATOM   7294  C  CB  . VAL E 1 135 ? 28.133  -40.35  0.855  1   51.06  ? 117 VAL A CB  1 
ATOM   7295  C  CG1 . VAL E 1 135 ? 28.369  -39.645 -0.472 1   51.58  ? 117 VAL A CG1 1 
ATOM   7296  C  CG2 . VAL E 1 135 ? 27.181  -39.541 1.726  1   50.63  ? 117 VAL A CG2 1 
ATOM   7297  N  N   . SER E 1 136 ? 28.378  -43.245 -1.19  1   53.82  ? 118 SER A N   1 
ATOM   7298  C  CA  . SER E 1 136 ? 29.182  -44.308 -1.847 1   57.08  ? 118 SER A CA  1 
ATOM   7299  C  C   . SER E 1 136 ? 28.804  -44.421 -3.33  1   59.16  ? 118 SER A C   1 
ATOM   7300  O  O   . SER E 1 136 ? 27.622  -44.185 -3.667 1   54.05  ? 118 SER A O   1 
ATOM   7301  C  CB  . SER E 1 136 ? 28.997  -45.628 -1.127 1   58.9   ? 118 SER A CB  1 
ATOM   7302  O  OG  . SER E 1 136 ? 29.905  -46.613 -1.599 1   60.06  ? 118 SER A OG  1 
ATOM   7303  N  N   . SER E 1 137 ? 29.787  -44.763 -4.172 1   63.02  ? 119 SER A N   1 
ATOM   7304  C  CA  . SER E 1 137 ? 29.635  -45.044 -5.625 1   65.56  ? 119 SER A CA  1 
ATOM   7305  C  C   . SER E 1 137 ? 29.013  -46.43  -5.841 1   64.4   ? 119 SER A C   1 
ATOM   7306  O  O   . SER E 1 137 ? 28.515  -46.676 -6.957 1   69.02  ? 119 SER A O   1 
ATOM   7307  C  CB  . SER E 1 137 ? 30.957  -44.936 -6.344 1   68.34  ? 119 SER A CB  1 
ATOM   7308  O  OG  . SER E 1 137 ? 31.442  -43.601 -6.318 1   72.99  ? 119 SER A OG  1 
ATOM   7309  N  N   . ALA E 1 138 ? 29.048  -47.3   -4.824 1   58.88  ? 120 ALA A N   1 
ATOM   7310  C  CA  . ALA E 1 138 ? 28.526  -48.687 -4.865 1   57.03  ? 120 ALA A CA  1 
ATOM   7311  C  C   . ALA E 1 138 ? 27.009  -48.686 -5.087 1   55.69  ? 120 ALA A C   1 
ATOM   7312  O  O   . ALA E 1 138 ? 26.401  -47.6   -5.059 1   55.63  ? 120 ALA A O   1 
ATOM   7313  C  CB  . ALA E 1 138 ? 28.897  -49.407 -3.591 1   57.62  ? 120 ALA A CB  1 
ATOM   7314  N  N   . SER E 1 139 ? 26.433  -49.873 -5.306 1   55.89  ? 121 SER A N   1 
ATOM   7315  C  CA  . SER E 1 139 ? 24.989  -50.11  -5.583 1   55.64  ? 121 SER A CA  1 
ATOM   7316  C  C   . SER E 1 139 ? 24.307  -50.72  -4.353 1   54.09  ? 121 SER A C   1 
ATOM   7317  O  O   . SER E 1 139 ? 24.966  -51.505 -3.639 1   54     ? 121 SER A O   1 
ATOM   7318  C  CB  . SER E 1 139 ? 24.816  -51.005 -6.78  1   56.62  ? 121 SER A CB  1 
ATOM   7319  O  OG  . SER E 1 139 ? 25.475  -50.467 -7.914 1   59.69  ? 121 SER A OG  1 
ATOM   7320  N  N   . THR E 1 140 ? 23.032  -50.381 -4.13  1   51.37  ? 122 THR A N   1 
ATOM   7321  C  CA  . THR E 1 140 ? 22.167  -50.973 -3.073 1   51.2   ? 122 THR A CA  1 
ATOM   7322  C  C   . THR E 1 140 ? 21.897  -52.434 -3.435 1   51.76  ? 122 THR A C   1 
ATOM   7323  O  O   . THR E 1 140 ? 21.528  -52.68  -4.599 1   54.65  ? 122 THR A O   1 
ATOM   7324  C  CB  . THR E 1 140 ? 20.843  -50.212 -2.919 1   49.62  ? 122 THR A CB  1 
ATOM   7325  O  OG1 . THR E 1 140 ? 21.141  -48.888 -2.483 1   50.81  ? 122 THR A OG1 1 
ATOM   7326  C  CG2 . THR E 1 140 ? 19.893  -50.846 -1.929 1   49.24  ? 122 THR A CG2 1 
ATOM   7327  N  N   . LYS E 1 141 ? 22.072  -53.353 -2.481 1   52.35  ? 123 LYS A N   1 
ATOM   7328  C  CA  . LYS E 1 141 ? 21.736  -54.793 -2.644 1   54.49  ? 123 LYS A CA  1 
ATOM   7329  C  C   . LYS E 1 141 ? 20.974  -55.277 -1.407 1   51.05  ? 123 LYS A C   1 
ATOM   7330  O  O   . LYS E 1 141 ? 21.484  -55.092 -0.285 1   48.86  ? 123 LYS A O   1 
ATOM   7331  C  CB  . LYS E 1 141 ? 22.989  -55.642 -2.88  1   56.67  ? 123 LYS A CB  1 
ATOM   7332  C  CG  . LYS E 1 141 ? 22.704  -57.114 -3.16  1   59.63  ? 123 LYS A CG  1 
ATOM   7333  C  CD  . LYS E 1 141 ? 23.875  -57.874 -3.752 1   63.66  ? 123 LYS A CD  1 
ATOM   7334  C  CE  . LYS E 1 141 ? 23.494  -59.248 -4.269 1   64.94  ? 123 LYS A CE  1 
ATOM   7335  N  NZ  . LYS E 1 141 ? 22.957  -60.117 -3.195 1   65.83  ? 123 LYS A NZ  1 
ATOM   7336  N  N   . GLY E 1 142 ? 19.801  -55.88  -1.622 1   48.65  ? 124 GLY A N   1 
ATOM   7337  C  CA  . GLY E 1 142 ? 18.96   -56.461 -0.561 1   47.51  ? 124 GLY A CA  1 
ATOM   7338  C  C   . GLY E 1 142 ? 19.584  -57.731 0.013  1   46.13  ? 124 GLY A C   1 
ATOM   7339  O  O   . GLY E 1 142 ? 20.264  -58.471 -0.701 1   43.28  ? 124 GLY A O   1 
ATOM   7340  N  N   . PRO E 1 143 ? 19.369  -58.026 1.316  1   45.57  ? 125 PRO A N   1 
ATOM   7341  C  CA  . PRO E 1 143 ? 19.9    -59.241 1.925  1   45.84  ? 125 PRO A CA  1 
ATOM   7342  C  C   . PRO E 1 143 ? 19.127  -60.495 1.501  1   44.07  ? 125 PRO A C   1 
ATOM   7343  O  O   . PRO E 1 143 ? 17.973  -60.383 1.149  1   45.36  ? 125 PRO A O   1 
ATOM   7344  C  CB  . PRO E 1 143 ? 19.7    -59.018 3.431  1   47.41  ? 125 PRO A CB  1 
ATOM   7345  C  CG  . PRO E 1 143 ? 18.513  -58.085 3.518  1   47.11  ? 125 PRO A CG  1 
ATOM   7346  C  CD  . PRO E 1 143 ? 18.593  -57.222 2.274  1   47.52  ? 125 PRO A CD  1 
ATOM   7347  N  N   . SER E 1 144 ? 19.799  -61.644 1.553  1   43.07  ? 126 SER A N   1 
ATOM   7348  C  CA  . SER E 1 144 ? 19.19   -62.996 1.563  1   43.12  ? 126 SER A CA  1 
ATOM   7349  C  C   . SER E 1 144 ? 19.162  -63.478 3.012  1   41.95  ? 126 SER A C   1 
ATOM   7350  O  O   . SER E 1 144 ? 20.241  -63.51  3.624  1   44.32  ? 126 SER A O   1 
ATOM   7351  C  CB  . SER E 1 144 ? 19.95   -63.939 0.673  1   43.36  ? 126 SER A CB  1 
ATOM   7352  O  OG  . SER E 1 144 ? 19.871  -63.514 -0.68  1   44.84  ? 126 SER A OG  1 
ATOM   7353  N  N   . VAL E 1 145 ? 17.975  -63.791 3.54   1   39.97  ? 127 VAL A N   1 
ATOM   7354  C  CA  . VAL E 1 145 ? 17.765  -64.302 4.929  1   38     ? 127 VAL A CA  1 
ATOM   7355  C  C   . VAL E 1 145 ? 17.686  -65.832 4.871  1   37.15  ? 127 VAL A C   1 
ATOM   7356  O  O   . VAL E 1 145 ? 16.923  -66.355 4.045  1   36.73  ? 127 VAL A O   1 
ATOM   7357  C  CB  . VAL E 1 145 ? 16.5    -63.698 5.567  1   36.73  ? 127 VAL A CB  1 
ATOM   7358  C  CG1 . VAL E 1 145 ? 16.302  -64.164 7      1   37.4   ? 127 VAL A CG1 1 
ATOM   7359  C  CG2 . VAL E 1 145 ? 16.519  -62.183 5.511  1   36.55  ? 127 VAL A CG2 1 
ATOM   7360  N  N   . PHE E 1 146 ? 18.442  -66.522 5.724  1   38.7   ? 128 PHE A N   1 
ATOM   7361  C  CA  . PHE E 1 146 ? 18.413  -68.001 5.863  1   40.38  ? 128 PHE A CA  1 
ATOM   7362  C  C   . PHE E 1 146 ? 18.212  -68.363 7.328  1   42.62  ? 128 PHE A C   1 
ATOM   7363  O  O   . PHE E 1 146 ? 18.759  -67.691 8.204  1   42.02  ? 128 PHE A O   1 
ATOM   7364  C  CB  . PHE E 1 146 ? 19.694  -68.637 5.321  1   39.96  ? 128 PHE A CB  1 
ATOM   7365  C  CG  . PHE E 1 146 ? 19.948  -68.344 3.866  1   41.25  ? 128 PHE A CG  1 
ATOM   7366  C  CD1 . PHE E 1 146 ? 19.126  -68.882 2.886  1   41.83  ? 128 PHE A CD1 1 
ATOM   7367  C  CD2 . PHE E 1 146 ? 20.987  -67.509 3.477  1   42.8   ? 128 PHE A CD2 1 
ATOM   7368  C  CE1 . PHE E 1 146 ? 19.346  -68.599 1.546  1   43.61  ? 128 PHE A CE1 1 
ATOM   7369  C  CE2 . PHE E 1 146 ? 21.21   -67.231 2.135  1   43.32  ? 128 PHE A CE2 1 
ATOM   7370  C  CZ  . PHE E 1 146 ? 20.388  -67.775 1.173  1   44.27  ? 128 PHE A CZ  1 
ATOM   7371  N  N   . PRO E 1 147 ? 17.446  -69.44  7.629  1   42.64  ? 129 PRO A N   1 
ATOM   7372  C  CA  . PRO E 1 147 ? 17.275  -69.904 9.001  1   42.1   ? 129 PRO A CA  1 
ATOM   7373  C  C   . PRO E 1 147 ? 18.528  -70.654 9.463  1   42.21  ? 129 PRO A C   1 
ATOM   7374  O  O   . PRO E 1 147 ? 19.032  -71.459 8.704  1   40.95  ? 129 PRO A O   1 
ATOM   7375  C  CB  . PRO E 1 147 ? 16.076  -70.854 8.902  1   42.74  ? 129 PRO A CB  1 
ATOM   7376  C  CG  . PRO E 1 147 ? 16.199  -71.44  7.512  1   41.87  ? 129 PRO A CG  1 
ATOM   7377  C  CD  . PRO E 1 147 ? 16.743  -70.307 6.666  1   42.64  ? 129 PRO A CD  1 
ATOM   7378  N  N   . LEU E 1 148 ? 18.995  -70.351 10.676 1   42.68  ? 130 LEU A N   1 
ATOM   7379  C  CA  . LEU E 1 148 ? 20.026  -71.132 11.405 1   40.85  ? 130 LEU A CA  1 
ATOM   7380  C  C   . LEU E 1 148 ? 19.303  -72.05  12.394 1   40.74  ? 130 LEU A C   1 
ATOM   7381  O  O   . LEU E 1 148 ? 19.036  -71.613 13.533 1   41.66  ? 130 LEU A O   1 
ATOM   7382  C  CB  . LEU E 1 148 ? 20.996  -70.161 12.082 1   40.65  ? 130 LEU A CB  1 
ATOM   7383  C  CG  . LEU E 1 148 ? 21.673  -69.17  11.137 1   41.73  ? 130 LEU A CG  1 
ATOM   7384  C  CD1 . LEU E 1 148 ? 22.596  -68.234 11.901 1   42.58  ? 130 LEU A CD1 1 
ATOM   7385  C  CD2 . LEU E 1 148 ? 22.44   -69.9   10.042 1   42.29  ? 130 LEU A CD2 1 
ATOM   7386  N  N   . ALA E 1 149 ? 18.958  -73.257 11.93  1   40.48  ? 131 ALA A N   1 
ATOM   7387  C  CA  . ALA E 1 149 ? 18.1    -74.244 12.624 1   42.72  ? 131 ALA A CA  1 
ATOM   7388  C  C   . ALA E 1 149 ? 18.756  -74.687 13.929 1   44.3   ? 131 ALA A C   1 
ATOM   7389  O  O   . ALA E 1 149 ? 19.973  -74.801 14     1   43.57  ? 131 ALA A O   1 
ATOM   7390  C  CB  . ALA E 1 149 ? 17.832  -75.423 11.722 1   43.62  ? 131 ALA A CB  1 
ATOM   7391  N  N   . PRO E 1 150 ? 17.981  -74.941 15.008 1   48.46  ? 132 PRO A N   1 
ATOM   7392  C  CA  . PRO E 1 150 ? 18.559  -75.419 16.266 1   51.68  ? 132 PRO A CA  1 
ATOM   7393  C  C   . PRO E 1 150 ? 19.076  -76.867 16.208 1   55.89  ? 132 PRO A C   1 
ATOM   7394  O  O   . PRO E 1 150 ? 18.715  -77.592 15.297 1   55.56  ? 132 PRO A O   1 
ATOM   7395  C  CB  . PRO E 1 150 ? 17.4    -75.283 17.266 1   49.55  ? 132 PRO A CB  1 
ATOM   7396  C  CG  . PRO E 1 150 ? 16.153  -75.365 16.414 1   49.14  ? 132 PRO A CG  1 
ATOM   7397  C  CD  . PRO E 1 150 ? 16.527  -74.741 15.09  1   47.15  ? 132 PRO A CD  1 
ATOM   7398  N  N   . SER E 1 151 ? 19.893  -77.241 17.201 1   64.07  ? 133 SER A N   1 
ATOM   7399  C  CA  . SER E 1 151 ? 20.514  -78.582 17.379 1   70.86  ? 133 SER A CA  1 
ATOM   7400  C  C   . SER E 1 151 ? 19.444  -79.664 17.591 1   82.58  ? 133 SER A C   1 
ATOM   7401  O  O   . SER E 1 151 ? 18.307  -79.318 17.982 1   84.62  ? 133 SER A O   1 
ATOM   7402  C  CB  . SER E 1 151 ? 21.495  -78.563 18.523 1   68.83  ? 133 SER A CB  1 
ATOM   7403  O  OG  . SER E 1 151 ? 22.151  -79.814 18.647 1   71.57  ? 133 SER A OG  1 
ATOM   7404  N  N   . SER E 1 152 ? 19.823  -80.932 17.379 1   98.78  ? 134 SER A N   1 
ATOM   7405  C  CA  . SER E 1 152 ? 18.928  -82.124 17.347 1   106.98 ? 134 SER A CA  1 
ATOM   7406  C  C   . SER E 1 152 ? 18.378  -82.454 18.741 1   111.63 ? 134 SER A C   1 
ATOM   7407  O  O   . SER E 1 152 ? 17.18   -82.794 18.823 1   113.49 ? 134 SER A O   1 
ATOM   7408  C  CB  . SER E 1 152 ? 19.633  -83.317 16.754 1   111.82 ? 134 SER A CB  1 
ATOM   7409  O  OG  . SER E 1 152 ? 20.64   -83.814 17.626 1   119.75 ? 134 SER A OG  1 
ATOM   7410  N  N   . LYS E 1 153 ? 19.222  -82.393 19.78  1   117.03 ? 135 LYS A N   1 
ATOM   7411  C  CA  . LYS E 1 153 ? 18.835  -82.643 21.198 1   120.82 ? 135 LYS A CA  1 
ATOM   7412  C  C   . LYS E 1 153 ? 17.784  -81.604 21.617 1   125.84 ? 135 LYS A C   1 
ATOM   7413  O  O   . LYS E 1 153 ? 18.18   -80.453 21.916 1   129.36 ? 135 LYS A O   1 
ATOM   7414  C  CB  . LYS E 1 153 ? 20.067  -82.608 22.111 1   120.64 ? 135 LYS A CB  1 
ATOM   7415  C  CG  . LYS E 1 153 ? 21.064  -83.741 21.899 1   121.29 ? 135 LYS A CG  1 
ATOM   7416  C  CD  . LYS E 1 153 ? 22.282  -83.675 22.773 0   123.97 ? 135 LYS A CD  1 
ATOM   7417  C  CE  . LYS E 1 153 ? 23.246  -84.819 22.541 0   123.97 ? 135 LYS A CE  1 
ATOM   7418  N  NZ  . LYS E 1 153 ? 24.441  -84.715 23.412 0   123.94 ? 135 LYS A NZ  1 
ATOM   7419  N  N   . SER E 1 154 ? 16.5    -81.999 21.609 1   126.12 ? 136 SER A N   1 
ATOM   7420  C  CA  . SER E 1 154 ? 15.309  -81.141 21.871 1   123.97 ? 136 SER A CA  1 
ATOM   7421  C  C   . SER E 1 154 ? 14.524  -81.645 23.094 1   129.55 ? 136 SER A C   1 
ATOM   7422  O  O   . SER E 1 154 ? 13.295  -81.413 23.138 1   131.26 ? 136 SER A O   1 
ATOM   7423  C  CB  . SER E 1 154 ? 14.416  -81.077 20.648 1   117.45 ? 136 SER A CB  1 
ATOM   7424  O  OG  . SER E 1 154 ? 15.148  -80.708 19.49  1   114.55 ? 136 SER A OG  1 
ATOM   7425  N  N   . THR E 1 155 ? 15.192  -82.298 24.055 1   133.36 ? 137 THR A N   1 
ATOM   7426  C  CA  . THR E 1 155 ? 14.567  -82.847 25.292 1   135.66 ? 137 THR A CA  1 
ATOM   7427  C  C   . THR E 1 155 ? 15.633  -83.024 26.382 1   135.53 ? 137 THR A C   1 
ATOM   7428  O  O   . THR E 1 155 ? 16.252  -84.108 26.44  1   137.8  ? 137 THR A O   1 
ATOM   7429  C  CB  . THR E 1 155 ? 13.816  -84.154 24.998 1   135.69 ? 137 THR A CB  1 
ATOM   7430  O  OG1 . THR E 1 155 ? 12.804  -83.917 24.023 0   138.89 ? 137 THR A OG1 1 
ATOM   7431  C  CG2 . THR E 1 155 ? 13.107  -84.712 26.255 0   138.92 ? 137 THR A CG2 1 
ATOM   7432  N  N   . SER E 1 156 ? 15.831  -81.985 27.2   1   131.61 ? 138 SER A N   1 
ATOM   7433  C  CA  . SER E 1 156 ? 16.728  -81.963 28.389 1   126.11 ? 138 SER A CA  1 
ATOM   7434  C  C   . SER E 1 156 ? 16.464  -80.689 29.207 1   122.44 ? 138 SER A C   1 
ATOM   7435  O  O   . SER E 1 156 ? 15.58   -79.899 28.804 1   127.64 ? 138 SER A O   1 
ATOM   7436  C  CB  . SER E 1 156 ? 18.18   -82.076 27.973 1   123.49 ? 138 SER A CB  1 
ATOM   7437  O  OG  . SER E 1 156 ? 18.53   -81.053 27.05  1   123.92 ? 138 SER A OG  1 
ATOM   7438  N  N   . GLY E 1 157 ? 17.194  -80.499 30.313 1   110.83 ? 139 GLY A N   1 
ATOM   7439  C  CA  . GLY E 1 157 ? 17.163  -79.267 31.128 1   102.48 ? 139 GLY A CA  1 
ATOM   7440  C  C   . GLY E 1 157 ? 17.882  -78.093 30.469 1   99.54  ? 139 GLY A C   1 
ATOM   7441  O  O   . GLY E 1 157 ? 17.644  -76.952 30.919 1   98.1   ? 139 GLY A O   1 
ATOM   7442  N  N   . GLY E 1 158 ? 18.728  -78.345 29.455 1   92.66  ? 140 GLY A N   1 
ATOM   7443  C  CA  . GLY E 1 158 ? 19.611  -77.348 28.813 1   82.73  ? 140 GLY A CA  1 
ATOM   7444  C  C   . GLY E 1 158 ? 18.933  -76.57  27.695 1   74.75  ? 140 GLY A C   1 
ATOM   7445  O  O   . GLY E 1 158 ? 17.772  -76.88  27.361 1   71.76  ? 140 GLY A O   1 
ATOM   7446  N  N   . THR E 1 159 ? 19.652  -75.595 27.126 1   69.6   ? 141 THR A N   1 
ATOM   7447  C  CA  . THR E 1 159 ? 19.159  -74.629 26.104 1   65.42  ? 141 THR A CA  1 
ATOM   7448  C  C   . THR E 1 159 ? 19.542  -75.1   24.693 1   60.53  ? 141 THR A C   1 
ATOM   7449  O  O   . THR E 1 159 ? 20.266  -76.114 24.576 1   55.07  ? 141 THR A O   1 
ATOM   7450  C  CB  . THR E 1 159 ? 19.716  -73.22  26.352 1   63.94  ? 141 THR A CB  1 
ATOM   7451  O  OG1 . THR E 1 159 ? 21.125  -73.25  26.126 1   66.01  ? 141 THR A OG1 1 
ATOM   7452  C  CG2 . THR E 1 159 ? 19.442  -72.697 27.745 1   64.29  ? 141 THR A CG2 1 
ATOM   7453  N  N   . ALA E 1 160 ? 19.055  -74.384 23.672 1   56.23  ? 142 ALA A N   1 
ATOM   7454  C  CA  . ALA E 1 160 ? 19.399  -74.557 22.24  1   51.91  ? 142 ALA A CA  1 
ATOM   7455  C  C   . ALA E 1 160 ? 19.525  -73.183 21.569 1   48.17  ? 142 ALA A C   1 
ATOM   7456  O  O   . ALA E 1 160 ? 18.674  -72.31  21.841 1   47.66  ? 142 ALA A O   1 
ATOM   7457  C  CB  . ALA E 1 160 ? 18.355  -75.406 21.558 1   50.91  ? 142 ALA A CB  1 
ATOM   7458  N  N   . ALA E 1 161 ? 20.554  -73.005 20.732 1   44.28  ? 143 ALA A N   1 
ATOM   7459  C  CA  . ALA E 1 161 ? 20.799  -71.791 19.918 1   42.11  ? 143 ALA A CA  1 
ATOM   7460  C  C   . ALA E 1 161 ? 20.178  -71.981 18.533 1   41.5   ? 143 ALA A C   1 
ATOM   7461  O  O   . ALA E 1 161 ? 20.415  -73.035 17.909 1   43.15  ? 143 ALA A O   1 
ATOM   7462  C  CB  . ALA E 1 161 ? 22.276  -71.514 19.808 1   41.99  ? 143 ALA A CB  1 
ATOM   7463  N  N   . LEU E 1 162 ? 19.392  -71.002 18.092 1   41.17  ? 144 LEU A N   1 
ATOM   7464  C  CA  . LEU E 1 162 ? 18.868  -70.887 16.706 1   42.4   ? 144 LEU A CA  1 
ATOM   7465  C  C   . LEU E 1 162 ? 19.022  -69.426 16.278 1   43.51  ? 144 LEU A C   1 
ATOM   7466  O  O   . LEU E 1 162 ? 19.205  -68.576 17.169 1   42.79  ? 144 LEU A O   1 
ATOM   7467  C  CB  . LEU E 1 162 ? 17.411  -71.358 16.661 1   43.03  ? 144 LEU A CB  1 
ATOM   7468  C  CG  . LEU E 1 162 ? 16.42   -70.596 17.546 1   44.07  ? 144 LEU A CG  1 
ATOM   7469  C  CD1 . LEU E 1 162 ? 15.652  -69.556 16.744 1   43.76  ? 144 LEU A CD1 1 
ATOM   7470  C  CD2 . LEU E 1 162 ? 15.445  -71.555 18.214 1   45.53  ? 144 LEU A CD2 1 
ATOM   7471  N  N   . GLY E 1 163 ? 18.963  -69.137 14.976 1   43.9   ? 145 GLY A N   1 
ATOM   7472  C  CA  . GLY E 1 163 ? 19.252  -67.779 14.482 1   42.5   ? 145 GLY A CA  1 
ATOM   7473  C  C   . GLY E 1 163 ? 18.758  -67.509 13.076 1   42.57  ? 145 GLY A C   1 
ATOM   7474  O  O   . GLY E 1 163 ? 17.999  -68.329 12.52  1   39.49  ? 145 GLY A O   1 
ATOM   7475  N  N   . CYS E 1 164 ? 19.166  -66.359 12.542 1   43.85  ? 146 CYS A N   1 
ATOM   7476  C  CA  . CYS E 1 164 ? 18.92   -65.913 11.15  1   45.09  ? 146 CYS A CA  1 
ATOM   7477  C  C   . CYS E 1 164 ? 20.227  -65.362 10.575 1   43.45  ? 146 CYS A C   1 
ATOM   7478  O  O   . CYS E 1 164 ? 20.819  -64.471 11.209 1   43.68  ? 146 CYS A O   1 
ATOM   7479  C  CB  . CYS E 1 164 ? 17.805  -64.873 11.091 1   48.59  ? 146 CYS A CB  1 
ATOM   7480  S  SG  . CYS E 1 164 ? 16.164  -65.622 10.925 1   56.61  ? 146 CYS A SG  1 
ATOM   7481  N  N   . LEU E 1 165 ? 20.657  -65.905 9.434  1   42.33  ? 147 LEU A N   1 
ATOM   7482  C  CA  . LEU E 1 165 ? 21.792  -65.395 8.626  1   39.65  ? 147 LEU A CA  1 
ATOM   7483  C  C   . LEU E 1 165 ? 21.239  -64.382 7.625  1   38.8   ? 147 LEU A C   1 
ATOM   7484  O  O   . LEU E 1 165 ? 20.454  -64.791 6.763  1   40.3   ? 147 LEU A O   1 
ATOM   7485  C  CB  . LEU E 1 165 ? 22.465  -66.577 7.919  1   39.72  ? 147 LEU A CB  1 
ATOM   7486  C  CG  . LEU E 1 165 ? 23.66   -66.249 7.025  1   39.19  ? 147 LEU A CG  1 
ATOM   7487  C  CD1 . LEU E 1 165 ? 24.699  -65.413 7.757  1   38.76  ? 147 LEU A CD1 1 
ATOM   7488  C  CD2 . LEU E 1 165 ? 24.298  -67.529 6.508  1   39.73  ? 147 LEU A CD2 1 
ATOM   7489  N  N   . VAL E 1 166 ? 21.612  -63.11  7.764  1   39.31  ? 148 VAL A N   1 
ATOM   7490  C  CA  . VAL E 1 166 ? 21.228  -62.009 6.832  1   39.52  ? 148 VAL A CA  1 
ATOM   7491  C  C   . VAL E 1 166 ? 22.44   -61.745 5.932  1   41.56  ? 148 VAL A C   1 
ATOM   7492  O  O   . VAL E 1 166 ? 23.386  -61.063 6.38   1   43.48  ? 148 VAL A O   1 
ATOM   7493  C  CB  . VAL E 1 166 ? 20.759  -60.759 7.6    1   38.91  ? 148 VAL A CB  1 
ATOM   7494  C  CG1 . VAL E 1 166 ? 20.303  -59.657 6.658  1   38.96  ? 148 VAL A CG1 1 
ATOM   7495  C  CG2 . VAL E 1 166 ? 19.653  -61.096 8.591  1   37.98  ? 148 VAL A CG2 1 
ATOM   7496  N  N   . LYS E 1 167 ? 22.4    -62.283 4.713  1   41.97  ? 149 LYS A N   1 
ATOM   7497  C  CA  . LYS E 1 167 ? 23.58   -62.52  3.844  1   44.71  ? 149 LYS A CA  1 
ATOM   7498  C  C   . LYS E 1 167 ? 23.622  -61.496 2.703  1   42.89  ? 149 LYS A C   1 
ATOM   7499  O  O   . LYS E 1 167 ? 22.578  -61.297 2.06   1   42.7   ? 149 LYS A O   1 
ATOM   7500  C  CB  . LYS E 1 167 ? 23.49   -63.952 3.307  1   48.55  ? 149 LYS A CB  1 
ATOM   7501  C  CG  . LYS E 1 167 ? 24.759  -64.516 2.689  1   51.88  ? 149 LYS A CG  1 
ATOM   7502  C  CD  . LYS E 1 167 ? 25.842  -64.861 3.696  1   54.87  ? 149 LYS A CD  1 
ATOM   7503  C  CE  . LYS E 1 167 ? 27.206  -65.038 3.059  1   57.43  ? 149 LYS A CE  1 
ATOM   7504  N  NZ  . LYS E 1 167 ? 28.296  -64.736 4.016  1   60.05  ? 149 LYS A NZ  1 
ATOM   7505  N  N   . ASP E 1 168 ? 24.783  -60.863 2.489  1   42.74  ? 150 ASP A N   1 
ATOM   7506  C  CA  . ASP E 1 168 ? 25.173  -60.134 1.246  1   43.52  ? 150 ASP A CA  1 
ATOM   7507  C  C   . ASP E 1 168 ? 24.256  -58.931 0.986  1   41.7   ? 150 ASP A C   1 
ATOM   7508  O  O   . ASP E 1 168 ? 23.563  -58.926 -0.054 1   44.37  ? 150 ASP A O   1 
ATOM   7509  C  CB  . ASP E 1 168 ? 25.192  -61.08  0.04   1   43.85  ? 150 ASP A CB  1 
ATOM   7510  C  CG  . ASP E 1 168 ? 26.274  -62.138 0.116  1   46.74  ? 150 ASP A CG  1 
ATOM   7511  O  OD1 . ASP E 1 168 ? 27.258  -61.915 0.862  1   46.92  ? 150 ASP A OD1 1 
ATOM   7512  O  OD2 . ASP E 1 168 ? 26.127  -63.178 -0.571 1   50.03  ? 150 ASP A OD2 1 
ATOM   7513  N  N   . TYR E 1 169 ? 24.282  -57.93  1.867  1   39.05  ? 151 TYR A N   1 
ATOM   7514  C  CA  . TYR E 1 169 ? 23.531  -56.657 1.697  1   38.24  ? 151 TYR A CA  1 
ATOM   7515  C  C   . TYR E 1 169 ? 24.498  -55.47  1.668  1   37.78  ? 151 TYR A C   1 
ATOM   7516  O  O   . TYR E 1 169 ? 25.64   -55.576 2.15   1   39.89  ? 151 TYR A O   1 
ATOM   7517  C  CB  . TYR E 1 169 ? 22.475  -56.484 2.792  1   38.44  ? 151 TYR A CB  1 
ATOM   7518  C  CG  . TYR E 1 169 ? 23.01   -56.361 4.194  1   38.07  ? 151 TYR A CG  1 
ATOM   7519  C  CD1 . TYR E 1 169 ? 23.222  -57.486 4.973  1   38.67  ? 151 TYR A CD1 1 
ATOM   7520  C  CD2 . TYR E 1 169 ? 23.292  -55.121 4.751  1   36.9   ? 151 TYR A CD2 1 
ATOM   7521  C  CE1 . TYR E 1 169 ? 23.711  -57.388 6.266  1   39.09  ? 151 TYR A CE1 1 
ATOM   7522  C  CE2 . TYR E 1 169 ? 23.774  -55.005 6.045  1   37.62  ? 151 TYR A CE2 1 
ATOM   7523  C  CZ  . TYR E 1 169 ? 23.988  -56.144 6.803  1   38.44  ? 151 TYR A CZ  1 
ATOM   7524  O  OH  . TYR E 1 169 ? 24.468  -56.057 8.076  1   39.66  ? 151 TYR A OH  1 
ATOM   7525  N  N   . PHE E 1 170 ? 24.03   -54.358 1.103  1   37.86  ? 152 PHE A N   1 
ATOM   7526  C  CA  . PHE E 1 170 ? 24.713  -53.042 1.123  1   37.27  ? 152 PHE A CA  1 
ATOM   7527  C  C   . PHE E 1 170 ? 23.68   -51.939 0.901  1   37     ? 152 PHE A C   1 
ATOM   7528  O  O   . PHE E 1 170 ? 22.741  -52.136 0.139  1   38.95  ? 152 PHE A O   1 
ATOM   7529  C  CB  . PHE E 1 170 ? 25.797  -52.993 0.047  1   38.6   ? 152 PHE A CB  1 
ATOM   7530  C  CG  . PHE E 1 170 ? 26.672  -51.771 0.122  1   39.53  ? 152 PHE A CG  1 
ATOM   7531  C  CD1 . PHE E 1 170 ? 26.307  -50.597 -0.519 1   39.74  ? 152 PHE A CD1 1 
ATOM   7532  C  CD2 . PHE E 1 170 ? 27.841  -51.786 0.865  1   40.16  ? 152 PHE A CD2 1 
ATOM   7533  C  CE1 . PHE E 1 170 ? 27.1    -49.464 -0.421 1   41.05  ? 152 PHE A CE1 1 
ATOM   7534  C  CE2 . PHE E 1 170 ? 28.637  -50.653 0.955  1   40.78  ? 152 PHE A CE2 1 
ATOM   7535  C  CZ  . PHE E 1 170 ? 28.264  -49.494 0.314  1   40.05  ? 152 PHE A CZ  1 
ATOM   7536  N  N   . PRO E 1 171 ? 23.766  -50.767 1.569  1   37.23  ? 153 PRO A N   1 
ATOM   7537  C  CA  . PRO E 1 171 ? 24.726  -50.505 2.638  1   38.28  ? 153 PRO A CA  1 
ATOM   7538  C  C   . PRO E 1 171 ? 24.217  -51.047 3.983  1   38.91  ? 153 PRO A C   1 
ATOM   7539  O  O   . PRO E 1 171 ? 23.178  -51.669 4.017  1   37.73  ? 153 PRO A O   1 
ATOM   7540  C  CB  . PRO E 1 171 ? 24.762  -48.973 2.643  1   38.07  ? 153 PRO A CB  1 
ATOM   7541  C  CG  . PRO E 1 171 ? 23.323  -48.598 2.376  1   38.43  ? 153 PRO A CG  1 
ATOM   7542  C  CD  . PRO E 1 171 ? 22.859  -49.628 1.366  1   38.64  ? 153 PRO A CD  1 
ATOM   7543  N  N   . GLU E 1 172 ? 24.946  -50.769 5.065  1   40.02  ? 154 GLU A N   1 
ATOM   7544  C  CA  . GLU E 1 172 ? 24.401  -50.826 6.444  1   40.73  ? 154 GLU A CA  1 
ATOM   7545  C  C   . GLU E 1 172 ? 23.247  -49.821 6.538  1   41.08  ? 154 GLU A C   1 
ATOM   7546  O  O   . GLU E 1 172 ? 23.189  -48.881 5.744  1   39.29  ? 154 GLU A O   1 
ATOM   7547  C  CB  . GLU E 1 172 ? 25.508  -50.521 7.454  1   41.63  ? 154 GLU A CB  1 
ATOM   7548  C  CG  . GLU E 1 172 ? 26.563  -51.609 7.55   1   43.52  ? 154 GLU A CG  1 
ATOM   7549  C  CD  . GLU E 1 172 ? 26.405  -52.571 8.719  1   46.32  ? 154 GLU A CD  1 
ATOM   7550  O  OE1 . GLU E 1 172 ? 25.31   -53.179 8.855  1   46.55  ? 154 GLU A OE1 1 
ATOM   7551  O  OE2 . GLU E 1 172 ? 27.376  -52.706 9.498  1   46.89  ? 154 GLU A OE2 1 
ATOM   7552  N  N   . PRO E 1 173 ? 22.292  -49.952 7.491  1   39.52  ? 155 PRO A N   1 
ATOM   7553  C  CA  . PRO E 1 173 ? 22.2    -51.078 8.417  1   39.87  ? 155 PRO A CA  1 
ATOM   7554  C  C   . PRO E 1 173 ? 21.072  -52.08  8.139  1   39.96  ? 155 PRO A C   1 
ATOM   7555  O  O   . PRO E 1 173 ? 20.239  -51.834 7.294  1   39.9   ? 155 PRO A O   1 
ATOM   7556  C  CB  . PRO E 1 173 ? 21.851  -50.324 9.701  1   39.97  ? 155 PRO A CB  1 
ATOM   7557  C  CG  . PRO E 1 173 ? 20.858  -49.287 9.226  1   39.51  ? 155 PRO A CG  1 
ATOM   7558  C  CD  . PRO E 1 173 ? 21.267  -48.947 7.804  1   39.89  ? 155 PRO A CD  1 
ATOM   7559  N  N   . VAL E 1 174 ? 21.092  -53.173 8.897  1   41.55  ? 156 VAL A N   1 
ATOM   7560  C  CA  . VAL E 1 174 ? 19.997  -54.173 9.039  1   41.67  ? 156 VAL A CA  1 
ATOM   7561  C  C   . VAL E 1 174 ? 19.581  -54.174 10.51  1   41.68  ? 156 VAL A C   1 
ATOM   7562  O  O   . VAL E 1 174 ? 20.481  -54.157 11.378 1   43.39  ? 156 VAL A O   1 
ATOM   7563  C  CB  . VAL E 1 174 ? 20.469  -55.565 8.578  1   42.32  ? 156 VAL A CB  1 
ATOM   7564  C  CG1 . VAL E 1 174 ? 19.705  -56.7   9.247  1   43.68  ? 156 VAL A CG1 1 
ATOM   7565  C  CG2 . VAL E 1 174 ? 20.406  -55.693 7.066  1   42.06  ? 156 VAL A CG2 1 
ATOM   7566  N  N   . THR E 1 175 ? 18.276  -54.202 10.775 1   41.51  ? 157 THR A N   1 
ATOM   7567  C  CA  . THR E 1 175 ? 17.704  -54.461 12.122 1   42.23  ? 157 THR A CA  1 
ATOM   7568  C  C   . THR E 1 175 ? 17.093  -55.864 12.107 1   41.24  ? 157 THR A C   1 
ATOM   7569  O  O   . THR E 1 175 ? 16.447  -56.217 11.101 1   41.18  ? 157 THR A O   1 
ATOM   7570  C  CB  . THR E 1 175 ? 16.694  -53.38  12.535 1   43     ? 157 THR A CB  1 
ATOM   7571  O  OG1 . THR E 1 175 ? 15.527  -53.503 11.723 1   43.06  ? 157 THR A OG1 1 
ATOM   7572  C  CG2 . THR E 1 175 ? 17.243  -51.974 12.422 1   44.06  ? 157 THR A CG2 1 
ATOM   7573  N  N   . VAL E 1 176 ? 17.305  -56.63  13.176 1   41.22  ? 158 VAL A N   1 
ATOM   7574  C  CA  . VAL E 1 176 ? 16.657  -57.954 13.403 1   41.4   ? 158 VAL A CA  1 
ATOM   7575  C  C   . VAL E 1 176 ? 15.893  -57.883 14.728 1   41.5   ? 158 VAL A C   1 
ATOM   7576  O  O   . VAL E 1 176 ? 16.513  -57.522 15.745 1   42.38  ? 158 VAL A O   1 
ATOM   7577  C  CB  . VAL E 1 176 ? 17.677  -59.108 13.407 1   40.08  ? 158 VAL A CB  1 
ATOM   7578  C  CG1 . VAL E 1 176 ? 16.971  -60.453 13.461 1   39.89  ? 158 VAL A CG1 1 
ATOM   7579  C  CG2 . VAL E 1 176 ? 18.619  -59.049 12.21  1   39.52  ? 158 VAL A CG2 1 
ATOM   7580  N  N   . SER E 1 177 ? 14.594  -58.187 14.692 1   41.59  ? 159 SER A N   1 
ATOM   7581  C  CA  . SER E 1 177 ? 13.753  -58.498 15.876 1   43.4   ? 159 SER A CA  1 
ATOM   7582  C  C   . SER E 1 177 ? 13.249  -59.941 15.761 1   44.81  ? 159 SER A C   1 
ATOM   7583  O  O   . SER E 1 177 ? 13.27   -60.49  14.641 1   42.06  ? 159 SER A O   1 
ATOM   7584  C  CB  . SER E 1 177 ? 12.624  -57.512 16.023 1   42.34  ? 159 SER A CB  1 
ATOM   7585  O  OG  . SER E 1 177 ? 11.743  -57.57  14.915 1   42.18  ? 159 SER A OG  1 
ATOM   7586  N  N   . TRP E 1 178 ? 12.848  -60.535 16.887 1   47.12  ? 160 TRP A N   1 
ATOM   7587  C  CA  . TRP E 1 178 ? 12.262  -61.9   16.963 1   47.87  ? 160 TRP A CA  1 
ATOM   7588  C  C   . TRP E 1 178 ? 10.814  -61.797 17.456 1   48.78  ? 160 TRP A C   1 
ATOM   7589  O  O   . TRP E 1 178 ? 10.59   -61.146 18.495 1   52.76  ? 160 TRP A O   1 
ATOM   7590  C  CB  . TRP E 1 178 ? 13.126  -62.812 17.843 1   46.67  ? 160 TRP A CB  1 
ATOM   7591  C  CG  . TRP E 1 178 ? 14.428  -63.183 17.199 1   45.68  ? 160 TRP A CG  1 
ATOM   7592  C  CD1 . TRP E 1 178 ? 15.596  -62.482 17.258 1   45.39  ? 160 TRP A CD1 1 
ATOM   7593  C  CD2 . TRP E 1 178 ? 14.695  -64.331 16.373 1   44.58  ? 160 TRP A CD2 1 
ATOM   7594  N  NE1 . TRP E 1 178 ? 16.571  -63.116 16.537 1   43.9   ? 160 TRP A NE1 1 
ATOM   7595  C  CE2 . TRP E 1 178 ? 16.049  -64.251 15.98  1   45.18  ? 160 TRP A CE2 1 
ATOM   7596  C  CE3 . TRP E 1 178 ? 13.932  -65.416 15.926 1   43.93  ? 160 TRP A CE3 1 
ATOM   7597  C  CZ2 . TRP E 1 178 ? 16.651  -65.216 15.171 1   44.28  ? 160 TRP A CZ2 1 
ATOM   7598  C  CZ3 . TRP E 1 178 ? 14.526  -66.368 15.125 1   43.92  ? 160 TRP A CZ3 1 
ATOM   7599  C  CH2 . TRP E 1 178 ? 15.87   -66.27  14.758 1   43.26  ? 160 TRP A CH2 1 
ATOM   7600  N  N   . ASN E 1 179 ? 9.874   -62.389 16.713 1   47.55  ? 161 ASN A N   1 
ATOM   7601  C  CA  . ASN E 1 179 ? 8.423   -62.419 17.041 1   46.66  ? 161 ASN A CA  1 
ATOM   7602  C  C   . ASN E 1 179 ? 7.932   -60.98  17.27  1   47.53  ? 161 ASN A C   1 
ATOM   7603  O  O   . ASN E 1 179 ? 7.296   -60.715 18.307 1   50.2   ? 161 ASN A O   1 
ATOM   7604  C  CB  . ASN E 1 179 ? 8.154   -63.374 18.209 1   44.89  ? 161 ASN A CB  1 
ATOM   7605  C  CG  . ASN E 1 179 ? 8.488   -64.817 17.887 1   44.9   ? 161 ASN A CG  1 
ATOM   7606  O  OD1 . ASN E 1 179 ? 8.807   -65.153 16.748 1   43.9   ? 161 ASN A OD1 1 
ATOM   7607  N  ND2 . ASN E 1 179 ? 8.42    -65.686 18.886 1   45.22  ? 161 ASN A ND2 1 
ATOM   7608  N  N   . SER E 1 180 ? 8.247   -60.082 16.332 1   47.36  ? 162 SER A N   1 
ATOM   7609  C  CA  . SER E 1 180 ? 7.819   -58.657 16.293 1   46.02  ? 162 SER A CA  1 
ATOM   7610  C  C   . SER E 1 180 ? 8.169   -57.924 17.601 1   44.29  ? 162 SER A C   1 
ATOM   7611  O  O   . SER E 1 180 ? 7.397   -57.031 18.002 1   46.67  ? 162 SER A O   1 
ATOM   7612  C  CB  . SER E 1 180 ? 6.349   -58.572 15.981 1   47.04  ? 162 SER A CB  1 
ATOM   7613  O  OG  . SER E 1 180 ? 6.027   -59.374 14.854 1   48.75  ? 162 SER A OG  1 
ATOM   7614  N  N   . GLY E 1 181 ? 9.296   -58.272 18.232 1   42.34  ? 163 GLY A N   1 
ATOM   7615  C  CA  . GLY E 1 181 ? 9.809   -57.608 19.446 1   42.5   ? 163 GLY A CA  1 
ATOM   7616  C  C   . GLY E 1 181 ? 9.413   -58.312 20.735 1   43.78  ? 163 GLY A C   1 
ATOM   7617  O  O   . GLY E 1 181 ? 10.021  -57.983 21.767 1   45.26  ? 163 GLY A O   1 
ATOM   7618  N  N   . ALA E 1 182 ? 8.447   -59.242 20.694 1   43.63  ? 164 ALA A N   1 
ATOM   7619  C  CA  . ALA E 1 182 ? 7.941   -60.006 21.861 1   41.76  ? 164 ALA A CA  1 
ATOM   7620  C  C   . ALA E 1 182 ? 9.077   -60.803 22.511 1   44.14  ? 164 ALA A C   1 
ATOM   7621  O  O   . ALA E 1 182 ? 9.073   -60.919 23.758 1   48.05  ? 164 ALA A O   1 
ATOM   7622  C  CB  . ALA E 1 182 ? 6.824   -60.925 21.439 1   40.89  ? 164 ALA A CB  1 
ATOM   7623  N  N   . LEU E 1 183 ? 9.991   -61.349 21.7   1   43.21  ? 165 LEU A N   1 
ATOM   7624  C  CA  . LEU E 1 183 ? 11.135  -62.18  22.159 1   41.42  ? 165 LEU A CA  1 
ATOM   7625  C  C   . LEU E 1 183 ? 12.401  -61.314 22.171 1   42.9   ? 165 LEU A C   1 
ATOM   7626  O  O   . LEU E 1 183 ? 12.82   -60.854 21.09  1   42.76  ? 165 LEU A O   1 
ATOM   7627  C  CB  . LEU E 1 183 ? 11.266  -63.394 21.235 1   41.5   ? 165 LEU A CB  1 
ATOM   7628  C  CG  . LEU E 1 183 ? 12.357  -64.403 21.593 1   43.34  ? 165 LEU A CG  1 
ATOM   7629  C  CD1 . LEU E 1 183 ? 12.255  -64.87  23.039 1   44.33  ? 165 LEU A CD1 1 
ATOM   7630  C  CD2 . LEU E 1 183 ? 12.302  -65.595 20.655 1   43.32  ? 165 LEU A CD2 1 
ATOM   7631  N  N   . THR E 1 184 ? 12.937  -61.06  23.369 1   45     ? 166 THR A N   1 
ATOM   7632  C  CA  . THR E 1 184 ? 14.128  -60.207 23.639 1   46     ? 166 THR A CA  1 
ATOM   7633  C  C   . THR E 1 184 ? 15.133  -60.953 24.525 1   46.83  ? 166 THR A C   1 
ATOM   7634  O  O   . THR E 1 184 ? 16.343  -60.75  24.313 1   51.66  ? 166 THR A O   1 
ATOM   7635  C  CB  . THR E 1 184 ? 13.732  -58.879 24.3   1   45.73  ? 166 THR A CB  1 
ATOM   7636  O  OG1 . THR E 1 184 ? 13.192  -59.181 25.588 1   46.12  ? 166 THR A OG1 1 
ATOM   7637  C  CG2 . THR E 1 184 ? 12.735  -58.084 23.485 1   43.65  ? 166 THR A CG2 1 
ATOM   7638  N  N   . SER E 1 185 ? 14.661  -61.732 25.506 1   46.57  ? 167 SER A N   1 
ATOM   7639  C  CA  A SER E 1 185 ? 15.52   -62.554 26.4   0.5 46.24  ? 167 SER A CA  1 
ATOM   7640  C  CA  B SER E 1 185 ? 15.523  -62.55  26.4   0.5 46.15  ? 167 SER A CA  1 
ATOM   7641  C  C   . SER E 1 185 ? 16.291  -63.581 25.563 1   45.88  ? 167 SER A C   1 
ATOM   7642  O  O   . SER E 1 185 ? 15.642  -64.298 24.775 1   45.45  ? 167 SER A O   1 
ATOM   7643  C  CB  A SER E 1 185 ? 14.705  -63.223 27.478 0.5 45.76  ? 167 SER A CB  1 
ATOM   7644  C  CB  B SER E 1 185 ? 14.717  -63.212 27.49  0.5 45.56  ? 167 SER A CB  1 
ATOM   7645  O  OG  A SER E 1 185 ? 13.726  -64.08  26.911 0.5 45.5   ? 167 SER A OG  1 
ATOM   7646  O  OG  B SER E 1 185 ? 15.565  -63.888 28.406 0.5 45.03  ? 167 SER A OG  1 
ATOM   7647  N  N   . GLY E 1 186 ? 17.617  -63.622 25.723 1   46.93  ? 168 GLY A N   1 
ATOM   7648  C  CA  . GLY E 1 186 ? 18.517  -64.559 25.021 1   48.05  ? 168 GLY A CA  1 
ATOM   7649  C  C   . GLY E 1 186 ? 18.764  -64.175 23.569 1   47.49  ? 168 GLY A C   1 
ATOM   7650  O  O   . GLY E 1 186 ? 19.391  -64.978 22.861 1   48.2   ? 168 GLY A O   1 
ATOM   7651  N  N   . VAL E 1 187 ? 18.311  -62.997 23.135 1   46.59  ? 169 VAL A N   1 
ATOM   7652  C  CA  . VAL E 1 187 ? 18.491  -62.497 21.742 1   47.29  ? 169 VAL A CA  1 
ATOM   7653  C  C   . VAL E 1 187 ? 19.847  -61.797 21.687 1   46.94  ? 169 VAL A C   1 
ATOM   7654  O  O   . VAL E 1 187 ? 20.111  -60.981 22.58  1   48.24  ? 169 VAL A O   1 
ATOM   7655  C  CB  . VAL E 1 187 ? 17.343  -61.561 21.316 1   47.49  ? 169 VAL A CB  1 
ATOM   7656  C  CG1 . VAL E 1 187 ? 17.589  -60.917 19.958 1   48.38  ? 169 VAL A CG1 1 
ATOM   7657  C  CG2 . VAL E 1 187 ? 16.006  -62.291 21.32  1   47.6   ? 169 VAL A CG2 1 
ATOM   7658  N  N   . HIS E 1 188 ? 20.664  -62.132 20.684 1   47.36  ? 170 HIS A N   1 
ATOM   7659  C  CA  . HIS E 1 188 ? 21.978  -61.499 20.394 1   46.3   ? 170 HIS A CA  1 
ATOM   7660  C  C   . HIS E 1 188 ? 22.129  -61.313 18.879 1   45.29  ? 170 HIS A C   1 
ATOM   7661  O  O   . HIS E 1 188 ? 22.35   -62.325 18.178 1   43.94  ? 170 HIS A O   1 
ATOM   7662  C  CB  . HIS E 1 188 ? 23.117  -62.335 20.99  1   48.76  ? 170 HIS A CB  1 
ATOM   7663  C  CG  . HIS E 1 188 ? 24.45   -61.662 20.944 1   50.8   ? 170 HIS A CG  1 
ATOM   7664  N  ND1 . HIS E 1 188 ? 25.571  -62.233 21.503 1   51.42  ? 170 HIS A ND1 1 
ATOM   7665  C  CD2 . HIS E 1 188 ? 24.843  -60.473 20.43  1   52.03  ? 170 HIS A CD2 1 
ATOM   7666  C  CE1 . HIS E 1 188 ? 26.601  -61.433 21.317 1   53.69  ? 170 HIS A CE1 1 
ATOM   7667  N  NE2 . HIS E 1 188 ? 26.18   -60.341 20.669 1   51.86  ? 170 HIS A NE2 1 
ATOM   7668  N  N   . THR E 1 189 ? 22.009  -60.07  18.401 1   42.75  ? 171 THR A N   1 
ATOM   7669  C  CA  . THR E 1 189 ? 22.25   -59.68  16.987 1   42.26  ? 171 THR A CA  1 
ATOM   7670  C  C   . THR E 1 189 ? 23.698  -59.194 16.872 1   41.6   ? 171 THR A C   1 
ATOM   7671  O  O   . THR E 1 189 ? 24.017  -58.132 17.438 1   46     ? 171 THR A O   1 
ATOM   7672  C  CB  . THR E 1 189 ? 21.216  -58.653 16.514 1   42.82  ? 171 THR A CB  1 
ATOM   7673  O  OG1 . THR E 1 189 ? 19.937  -59.157 16.897 1   44.18  ? 171 THR A OG1 1 
ATOM   7674  C  CG2 . THR E 1 189 ? 21.251  -58.407 15.02  1   43.18  ? 171 THR A CG2 1 
ATOM   7675  N  N   . PHE E 1 190 ? 24.532  -59.945 16.154 1   38.57  ? 172 PHE A N   1 
ATOM   7676  C  CA  . PHE E 1 190 ? 25.994  -59.713 16.049 1   37.61  ? 172 PHE A CA  1 
ATOM   7677  C  C   . PHE E 1 190 ? 26.265  -58.559 15.089 1   36.25  ? 172 PHE A C   1 
ATOM   7678  O  O   . PHE E 1 190 ? 25.586  -58.424 14.077 1   35.69  ? 172 PHE A O   1 
ATOM   7679  C  CB  . PHE E 1 190 ? 26.713  -60.989 15.604 1   38     ? 172 PHE A CB  1 
ATOM   7680  C  CG  . PHE E 1 190 ? 26.874  -61.99  16.717 1   37.35  ? 172 PHE A CG  1 
ATOM   7681  C  CD1 . PHE E 1 190 ? 25.773  -62.652 17.239 1   36.74  ? 172 PHE A CD1 1 
ATOM   7682  C  CD2 . PHE E 1 190 ? 28.12   -62.236 17.272 1   37.46  ? 172 PHE A CD2 1 
ATOM   7683  C  CE1 . PHE E 1 190 ? 25.918  -63.553 18.283 1   36.96  ? 172 PHE A CE1 1 
ATOM   7684  C  CE2 . PHE E 1 190 ? 28.263  -63.139 18.315 1   38.12  ? 172 PHE A CE2 1 
ATOM   7685  C  CZ  . PHE E 1 190 ? 27.162  -63.791 18.823 1   37.47  ? 172 PHE A CZ  1 
ATOM   7686  N  N   . PRO E 1 191 ? 27.265  -57.694 15.369 1   36.26  ? 173 PRO A N   1 
ATOM   7687  C  CA  . PRO E 1 191 ? 27.73   -56.725 14.383 1   37.13  ? 173 PRO A CA  1 
ATOM   7688  C  C   . PRO E 1 191 ? 28.127  -57.414 13.07  1   37.82  ? 173 PRO A C   1 
ATOM   7689  O  O   . PRO E 1 191 ? 28.772  -58.458 13.108 1   37.82  ? 173 PRO A O   1 
ATOM   7690  C  CB  . PRO E 1 191 ? 28.951  -56.03  14.997 1   36.51  ? 173 PRO A CB  1 
ATOM   7691  C  CG  . PRO E 1 191 ? 28.995  -56.471 16.445 1   36.68  ? 173 PRO A CG  1 
ATOM   7692  C  CD  . PRO E 1 191 ? 27.987  -57.586 16.641 1   36.76  ? 173 PRO A CD  1 
ATOM   7693  N  N   . ALA E 1 192 ? 27.733  -56.801 11.955 1   39.38  ? 174 ALA A N   1 
ATOM   7694  C  CA  . ALA E 1 192 ? 27.943  -57.299 10.577 1   40.84  ? 174 ALA A CA  1 
ATOM   7695  C  C   . ALA E 1 192 ? 29.439  -57.4   10.265 1   40.49  ? 174 ALA A C   1 
ATOM   7696  O  O   . ALA E 1 192 ? 30.214  -56.568 10.771 1   41.39  ? 174 ALA A O   1 
ATOM   7697  C  CB  . ALA E 1 192 ? 27.249  -56.39  9.591  1   41.89  ? 174 ALA A CB  1 
ATOM   7698  N  N   . VAL E 1 193 ? 29.815  -58.419 9.49   1   41.3   ? 175 VAL A N   1 
ATOM   7699  C  CA  . VAL E 1 193 ? 31.146  -58.537 8.831  1   42.39  ? 175 VAL A CA  1 
ATOM   7700  C  C   . VAL E 1 193 ? 31.059  -57.777 7.506  1   42.22  ? 175 VAL A C   1 
ATOM   7701  O  O   . VAL E 1 193 ? 30.058  -57.958 6.8    1   42.32  ? 175 VAL A O   1 
ATOM   7702  C  CB  . VAL E 1 193 ? 31.572  -60.011 8.639  1   44.3   ? 175 VAL A CB  1 
ATOM   7703  C  CG1 . VAL E 1 193 ? 30.723  -60.78  7.634  1   44.3   ? 175 VAL A CG1 1 
ATOM   7704  C  CG2 . VAL E 1 193 ? 33.041  -60.124 8.263  1   45.6   ? 175 VAL A CG2 1 
ATOM   7705  N  N   . LEU E 1 194 ? 32.041  -56.924 7.212  1   43.82  ? 176 LEU A N   1 
ATOM   7706  C  CA  . LEU E 1 194 ? 32.278  -56.394 5.842  1   44.78  ? 176 LEU A CA  1 
ATOM   7707  C  C   . LEU E 1 194 ? 33.172  -57.396 5.103  1   46.51  ? 176 LEU A C   1 
ATOM   7708  O  O   . LEU E 1 194 ? 34.322  -57.602 5.539  1   47.68  ? 176 LEU A O   1 
ATOM   7709  C  CB  . LEU E 1 194 ? 32.922  -55.006 5.915  1   44.05  ? 176 LEU A CB  1 
ATOM   7710  C  CG  . LEU E 1 194 ? 33.318  -54.372 4.579  1   42.78  ? 176 LEU A CG  1 
ATOM   7711  C  CD1 . LEU E 1 194 ? 32.201  -54.468 3.551  1   43.49  ? 176 LEU A CD1 1 
ATOM   7712  C  CD2 . LEU E 1 194 ? 33.717  -52.919 4.778  1   41.93  ? 176 LEU A CD2 1 
ATOM   7713  N  N   . GLN E 1 195 ? 32.647  -58.012 4.046  1   48.88  ? 177 GLN A N   1 
ATOM   7714  C  CA  . GLN E 1 195 ? 33.332  -59.082 3.273  1   51.04  ? 177 GLN A CA  1 
ATOM   7715  C  C   . GLN E 1 195 ? 34.196  -58.446 2.176  1   51.24  ? 177 GLN A C   1 
ATOM   7716  O  O   . GLN E 1 195 ? 34.026  -57.242 1.892  1   47.84  ? 177 GLN A O   1 
ATOM   7717  C  CB  . GLN E 1 195 ? 32.29   -60.062 2.729  1   51.98  ? 177 GLN A CB  1 
ATOM   7718  C  CG  . GLN E 1 195 ? 31.467  -60.704 3.838  1   54.47  ? 177 GLN A CG  1 
ATOM   7719  C  CD  . GLN E 1 195 ? 30.49   -61.745 3.354  1   57.03  ? 177 GLN A CD  1 
ATOM   7720  O  OE1 . GLN E 1 195 ? 30.743  -62.946 3.457  1   65.63  ? 177 GLN A OE1 1 
ATOM   7721  N  NE2 . GLN E 1 195 ? 29.356  -61.292 2.839  1   55.89  ? 177 GLN A NE2 1 
ATOM   7722  N  N   . SER E 1 196 ? 35.089  -59.244 1.583  1   54.76  ? 178 SER A N   1 
ATOM   7723  C  CA  . SER E 1 196 ? 36.002  -58.858 0.474  1   54.36  ? 178 SER A CA  1 
ATOM   7724  C  C   . SER E 1 196 ? 35.202  -58.384 -0.75  1   52.92  ? 178 SER A C   1 
ATOM   7725  O  O   . SER E 1 196 ? 35.746  -57.567 -1.513 1   55.65  ? 178 SER A O   1 
ATOM   7726  C  CB  . SER E 1 196 ? 36.941  -59.993 0.12   1   55.83  ? 178 SER A CB  1 
ATOM   7727  O  OG  . SER E 1 196 ? 36.238  -61.213 -0.076 1   56.95  ? 178 SER A OG  1 
ATOM   7728  N  N   . SER E 1 197 ? 33.958  -58.857 -0.915 1   50.51  ? 179 SER A N   1 
ATOM   7729  C  CA  . SER E 1 197 ? 33.01   -58.455 -1.993 1   47.55  ? 179 SER A CA  1 
ATOM   7730  C  C   . SER E 1 197 ? 32.482  -57.026 -1.792 1   43.6   ? 179 SER A C   1 
ATOM   7731  O  O   . SER E 1 197 ? 31.871  -56.502 -2.741 1   40.44  ? 179 SER A O   1 
ATOM   7732  C  CB  . SER E 1 197 ? 31.859  -59.432 -2.091 1   47.42  ? 179 SER A CB  1 
ATOM   7733  O  OG  . SER E 1 197 ? 31.041  -59.37  -0.931 1   47.55  ? 179 SER A OG  1 
ATOM   7734  N  N   . GLY E 1 198 ? 32.65   -56.444 -0.597 1   43.06  ? 180 GLY A N   1 
ATOM   7735  C  CA  . GLY E 1 198 ? 32.123  -55.114 -0.228 1   42.71  ? 180 GLY A CA  1 
ATOM   7736  C  C   . GLY E 1 198 ? 30.693  -55.176 0.289  1   42.45  ? 180 GLY A C   1 
ATOM   7737  O  O   . GLY E 1 198 ? 30.141  -54.101 0.589  1   42.57  ? 180 GLY A O   1 
ATOM   7738  N  N   . LEU E 1 199 ? 30.11   -56.379 0.387  1   42.95  ? 181 LEU A N   1 
ATOM   7739  C  CA  . LEU E 1 199 ? 28.741  -56.623 0.915  1   42.21  ? 181 LEU A CA  1 
ATOM   7740  C  C   . LEU E 1 199 ? 28.856  -57.031 2.381  1   41.72  ? 181 LEU A C   1 
ATOM   7741  O  O   . LEU E 1 199 ? 29.835  -57.712 2.728  1   41.72  ? 181 LEU A O   1 
ATOM   7742  C  CB  . LEU E 1 199 ? 28.05   -57.722 0.099  1   41.9   ? 181 LEU A CB  1 
ATOM   7743  C  CG  . LEU E 1 199 ? 27.993  -57.499 -1.413 1   41.39  ? 181 LEU A CG  1 
ATOM   7744  C  CD1 . LEU E 1 199 ? 27.282  -58.655 -2.098 1   41.37  ? 181 LEU A CD1 1 
ATOM   7745  C  CD2 . LEU E 1 199 ? 27.314  -56.182 -1.759 1   40.37  ? 181 LEU A CD2 1 
ATOM   7746  N  N   . TYR E 1 200 ? 27.898  -56.608 3.204  1   41.3   ? 182 TYR A N   1 
ATOM   7747  C  CA  . TYR E 1 200 ? 27.815  -56.982 4.635  1   41.57  ? 182 TYR A CA  1 
ATOM   7748  C  C   . TYR E 1 200 ? 27.04   -58.297 4.752  1   41.09  ? 182 TYR A C   1 
ATOM   7749  O  O   . TYR E 1 200 ? 26.16   -58.568 3.916  1   43.65  ? 182 TYR A O   1 
ATOM   7750  C  CB  . TYR E 1 200 ? 27.173  -55.862 5.453  1   43.04  ? 182 TYR A CB  1 
ATOM   7751  C  CG  . TYR E 1 200 ? 27.95   -54.57  5.479  1   44.1   ? 182 TYR A CG  1 
ATOM   7752  C  CD1 . TYR E 1 200 ? 28.944  -54.347 6.419  1   44.01  ? 182 TYR A CD1 1 
ATOM   7753  C  CD2 . TYR E 1 200 ? 27.691  -53.562 4.561  1   45.79  ? 182 TYR A CD2 1 
ATOM   7754  C  CE1 . TYR E 1 200 ? 29.663  -53.161 6.443  1   44.29  ? 182 TYR A CE1 1 
ATOM   7755  C  CE2 . TYR E 1 200 ? 28.398  -52.369 4.574  1   45.12  ? 182 TYR A CE2 1 
ATOM   7756  C  CZ  . TYR E 1 200 ? 29.387  -52.167 5.519  1   44.75  ? 182 TYR A CZ  1 
ATOM   7757  O  OH  . TYR E 1 200 ? 30.072  -50.989 5.543  1   47.42  ? 182 TYR A OH  1 
ATOM   7758  N  N   . SER E 1 201 ? 27.396  -59.103 5.75   1   39.19  ? 183 SER A N   1 
ATOM   7759  C  CA  . SER E 1 201 ? 26.586  -60.228 6.281  1   38.93  ? 183 SER A CA  1 
ATOM   7760  C  C   . SER E 1 201 ? 26.48   -60.066 7.799  1   37.81  ? 183 SER A C   1 
ATOM   7761  O  O   . SER E 1 201 ? 27.462  -59.596 8.401  1   38.09  ? 183 SER A O   1 
ATOM   7762  C  CB  . SER E 1 201 ? 27.188  -61.557 5.912  1   39.24  ? 183 SER A CB  1 
ATOM   7763  O  OG  . SER E 1 201 ? 27.089  -61.785 4.515  1   40.36  ? 183 SER A OG  1 
ATOM   7764  N  N   . LEU E 1 202 ? 25.34   -60.408 8.4    1   36.62  ? 184 LEU A N   1 
ATOM   7765  C  CA  . LEU E 1 202 ? 25.24   -60.531 9.881  1   36.49  ? 184 LEU A CA  1 
ATOM   7766  C  C   . LEU E 1 202 ? 24.383  -61.739 10.248 1   35.42  ? 184 LEU A C   1 
ATOM   7767  O  O   . LEU E 1 202 ? 23.722  -62.32  9.357  1   33.66  ? 184 LEU A O   1 
ATOM   7768  C  CB  . LEU E 1 202 ? 24.72   -59.237 10.529 1   36.53  ? 184 LEU A CB  1 
ATOM   7769  C  CG  . LEU E 1 202 ? 23.281  -58.799 10.249 1   36.72  ? 184 LEU A CG  1 
ATOM   7770  C  CD1 . LEU E 1 202 ? 22.248  -59.677 10.945 1   37.26  ? 184 LEU A CD1 1 
ATOM   7771  C  CD2 . LEU E 1 202 ? 23.087  -57.361 10.704 1   37.49  ? 184 LEU A CD2 1 
ATOM   7772  N  N   . SER E 1 203 ? 24.42   -62.071 11.536 1   35.38  ? 185 SER A N   1 
ATOM   7773  C  CA  . SER E 1 203 ? 23.679  -63.187 12.165 1   36.46  ? 185 SER A CA  1 
ATOM   7774  C  C   . SER E 1 203 ? 23.025  -62.677 13.447 1   37.26  ? 185 SER A C   1 
ATOM   7775  O  O   . SER E 1 203 ? 23.657  -61.864 14.149 1   37.19  ? 185 SER A O   1 
ATOM   7776  C  CB  . SER E 1 203 ? 24.59   -64.355 12.426 1   36.65  ? 185 SER A CB  1 
ATOM   7777  O  OG  . SER E 1 203 ? 24.997  -64.96  11.205 1   34.9   ? 185 SER A OG  1 
ATOM   7778  N  N   . SER E 1 204 ? 21.787  -63.103 13.694 1   38.64  ? 186 SER A N   1 
ATOM   7779  C  CA  . SER E 1 204 ? 21.055  -62.927 14.974 1   38.38  ? 186 SER A CA  1 
ATOM   7780  C  C   . SER E 1 204 ? 20.747  -64.313 15.542 1   38.36  ? 186 SER A C   1 
ATOM   7781  O  O   . SER E 1 204 ? 20.125  -65.101 14.825 1   38.43  ? 186 SER A O   1 
ATOM   7782  C  CB  . SER E 1 204 ? 19.809  -62.117 14.774 1   38.46  ? 186 SER A CB  1 
ATOM   7783  O  OG  . SER E 1 204 ? 19.316  -61.654 16.018 1   39.34  ? 186 SER A OG  1 
ATOM   7784  N  N   . VAL E 1 205 ? 21.211  -64.605 16.758 1   38.73  ? 187 VAL A N   1 
ATOM   7785  C  CA  . VAL E 1 205 ? 21.004  -65.914 17.444 1   40.72  ? 187 VAL A CA  1 
ATOM   7786  C  C   . VAL E 1 205 ? 20.113  -65.684 18.673 1   42.53  ? 187 VAL A C   1 
ATOM   7787  O  O   . VAL E 1 205 ? 20.225  -64.607 19.294 1   42.86  ? 187 VAL A O   1 
ATOM   7788  C  CB  . VAL E 1 205 ? 22.351  -66.571 17.804 1   42.26  ? 187 VAL A CB  1 
ATOM   7789  C  CG1 . VAL E 1 205 ? 23.049  -65.884 18.969 1   44.28  ? 187 VAL A CG1 1 
ATOM   7790  C  CG2 . VAL E 1 205 ? 22.207  -68.061 18.077 1   41.7   ? 187 VAL A CG2 1 
ATOM   7791  N  N   . VAL E 1 206 ? 19.246  -66.646 18.999 1   43.85  ? 188 VAL A N   1 
ATOM   7792  C  CA  . VAL E 1 206 ? 18.453  -66.64  20.263 1   45.34  ? 188 VAL A CA  1 
ATOM   7793  C  C   . VAL E 1 206 ? 18.623  -67.996 20.959 1   46.19  ? 188 VAL A C   1 
ATOM   7794  O  O   . VAL E 1 206 ? 18.434  -69.042 20.31  1   44.39  ? 188 VAL A O   1 
ATOM   7795  C  CB  . VAL E 1 206 ? 16.979  -66.249 20.037 1   47.27  ? 188 VAL A CB  1 
ATOM   7796  C  CG1 . VAL E 1 206 ? 16.245  -67.198 19.102 1   50.7   ? 188 VAL A CG1 1 
ATOM   7797  C  CG2 . VAL E 1 206 ? 16.229  -66.1   21.352 1   47.42  ? 188 VAL A CG2 1 
ATOM   7798  N  N   . THR E 1 207 ? 19.03   -67.951 22.229 1   48.87  ? 189 THR A N   1 
ATOM   7799  C  CA  . THR E 1 207 ? 19.097  -69.105 23.157 1   49.73  ? 189 THR A CA  1 
ATOM   7800  C  C   . THR E 1 207 ? 17.696  -69.298 23.744 1   48.78  ? 189 THR A C   1 
ATOM   7801  O  O   . THR E 1 207 ? 17.144  -68.313 24.28  1   51.69  ? 189 THR A O   1 
ATOM   7802  C  CB  . THR E 1 207 ? 20.176  -68.878 24.223 1   51.57  ? 189 THR A CB  1 
ATOM   7803  O  OG1 . THR E 1 207 ? 21.397  -68.577 23.549 1   51.95  ? 189 THR A OG1 1 
ATOM   7804  C  CG2 . THR E 1 207 ? 20.397  -70.075 25.121 1   54.6   ? 189 THR A CG2 1 
ATOM   7805  N  N   . VAL E 1 208 ? 17.132  -70.5   23.602 1   47.28  ? 190 VAL A N   1 
ATOM   7806  C  CA  . VAL E 1 208 ? 15.758  -70.857 24.068 1   47.46  ? 190 VAL A CA  1 
ATOM   7807  C  C   . VAL E 1 208 ? 15.809  -72.238 24.714 1   48.12  ? 190 VAL A C   1 
ATOM   7808  O  O   . VAL E 1 208 ? 16.752  -72.991 24.465 1   50.23  ? 190 VAL A O   1 
ATOM   7809  C  CB  . VAL E 1 208 ? 14.745  -70.813 22.908 1   46.89  ? 190 VAL A CB  1 
ATOM   7810  C  CG1 . VAL E 1 208 ? 14.579  -69.402 22.376 1   48.04  ? 190 VAL A CG1 1 
ATOM   7811  C  CG2 . VAL E 1 208 ? 15.112  -71.763 21.777 1   47.45  ? 190 VAL A CG2 1 
ATOM   7812  N  N   . PRO E 1 209 ? 14.813  -72.615 25.553 1   48.08  ? 191 PRO A N   1 
ATOM   7813  C  CA  . PRO E 1 209 ? 14.74   -73.974 26.099 1   48.01  ? 191 PRO A CA  1 
ATOM   7814  C  C   . PRO E 1 209 ? 14.663  -75.044 24.997 1   48.39  ? 191 PRO A C   1 
ATOM   7815  O  O   . PRO E 1 209 ? 13.963  -74.826 24.029 1   47.68  ? 191 PRO A O   1 
ATOM   7816  C  CB  . PRO E 1 209 ? 13.449  -73.971 26.936 1   47.68  ? 191 PRO A CB  1 
ATOM   7817  C  CG  . PRO E 1 209 ? 13.194  -72.508 27.244 1   46.74  ? 191 PRO A CG  1 
ATOM   7818  C  CD  . PRO E 1 209 ? 13.72   -71.756 26.042 1   47.33  ? 191 PRO A CD  1 
ATOM   7819  N  N   . SER E 1 210 ? 15.389  -76.154 25.164 1   50.27  ? 192 SER A N   1 
ATOM   7820  C  CA  . SER E 1 210 ? 15.426  -77.301 24.217 1   54.26  ? 192 SER A CA  1 
ATOM   7821  C  C   . SER E 1 210 ? 14.063  -78     24.152 1   56.67  ? 192 SER A C   1 
ATOM   7822  O  O   . SER E 1 210 ? 13.621  -78.308 23.028 1   54.28  ? 192 SER A O   1 
ATOM   7823  C  CB  . SER E 1 210 ? 16.5    -78.278 24.591 1   57.28  ? 192 SER A CB  1 
ATOM   7824  O  OG  . SER E 1 210 ? 17.776  -77.686 24.446 1   64.14  ? 192 SER A OG  1 
ATOM   7825  N  N   . SER E 1 211 ? 13.434  -78.251 25.31  1   59.43  ? 193 SER A N   1 
ATOM   7826  C  CA  . SER E 1 211 ? 12.127  -78.955 25.455 1   59     ? 193 SER A CA  1 
ATOM   7827  C  C   . SER E 1 211 ? 11.032  -78.279 24.611 1   60.99  ? 193 SER A C   1 
ATOM   7828  O  O   . SER E 1 211 ? 10.151  -79.01  24.112 1   61.75  ? 193 SER A O   1 
ATOM   7829  C  CB  . SER E 1 211 ? 11.712  -79.055 26.905 1   55.74  ? 193 SER A CB  1 
ATOM   7830  O  OG  . SER E 1 211 ? 11.628  -77.771 27.501 1   53.99  ? 193 SER A OG  1 
ATOM   7831  N  N   . SER E 1 212 ? 11.112  -76.954 24.423 1   60.59  ? 194 SER A N   1 
ATOM   7832  C  CA  . SER E 1 212 ? 10.075  -76.096 23.789 1   61.4   ? 194 SER A CA  1 
ATOM   7833  C  C   . SER E 1 212 ? 10.345  -75.86  22.289 1   62     ? 194 SER A C   1 
ATOM   7834  O  O   . SER E 1 212 ? 9.771   -74.892 21.737 1   61.84  ? 194 SER A O   1 
ATOM   7835  C  CB  . SER E 1 212 ? 9.997   -74.783 24.541 1   63.42  ? 194 SER A CB  1 
ATOM   7836  O  OG  . SER E 1 212 ? 11.088  -73.93  24.203 1   64.46  ? 194 SER A OG  1 
ATOM   7837  N  N   . LEU E 1 213 ? 11.163  -76.692 21.63  1   59.25  ? 195 LEU A N   1 
ATOM   7838  C  CA  . LEU E 1 213 ? 11.636  -76.418 20.244 1   56.72  ? 195 LEU A CA  1 
ATOM   7839  C  C   . LEU E 1 213 ? 10.527  -76.716 19.232 1   57.22  ? 195 LEU A C   1 
ATOM   7840  O  O   . LEU E 1 213 ? 10.381  -75.914 18.283 1   59.85  ? 195 LEU A O   1 
ATOM   7841  C  CB  . LEU E 1 213 ? 12.914  -77.209 19.934 1   55.03  ? 195 LEU A CB  1 
ATOM   7842  C  CG  . LEU E 1 213 ? 14.225  -76.5   20.28  1   53.17  ? 195 LEU A CG  1 
ATOM   7843  C  CD1 . LEU E 1 213 ? 15.419  -77.391 19.984 1   52.06  ? 195 LEU A CD1 1 
ATOM   7844  C  CD2 . LEU E 1 213 ? 14.361  -75.182 19.532 1   50.89  ? 195 LEU A CD2 1 
ATOM   7845  N  N   . GLY E 1 214 ? 9.787   -77.813 19.424 1   58.57  ? 196 GLY A N   1 
ATOM   7846  C  CA  . GLY E 1 214 ? 8.678   -78.233 18.543 1   61.56  ? 196 GLY A CA  1 
ATOM   7847  C  C   . GLY E 1 214 ? 7.416   -77.406 18.752 1   62.23  ? 196 GLY A C   1 
ATOM   7848  O  O   . GLY E 1 214 ? 6.642   -77.25  17.78  1   63.31  ? 196 GLY A O   1 
ATOM   7849  N  N   . THR E 1 215 ? 7.22    -76.881 19.966 1   60.52  ? 197 THR A N   1 
ATOM   7850  C  CA  . THR E 1 215 ? 5.981   -76.196 20.424 1   57.48  ? 197 THR A CA  1 
ATOM   7851  C  C   . THR E 1 215 ? 6.014   -74.716 20.026 1   57.21  ? 197 THR A C   1 
ATOM   7852  O  O   . THR E 1 215 ? 5.037   -74.245 19.408 1   60.04  ? 197 THR A O   1 
ATOM   7853  C  CB  . THR E 1 215 ? 5.828   -76.345 21.941 1   54.92  ? 197 THR A CB  1 
ATOM   7854  O  OG1 . THR E 1 215 ? 6.957   -75.731 22.561 1   55.61  ? 197 THR A OG1 1 
ATOM   7855  C  CG2 . THR E 1 215 ? 5.727   -77.788 22.383 1   55.09  ? 197 THR A CG2 1 
ATOM   7856  N  N   . GLN E 1 216 ? 7.098   -74.019 20.38  1   53.87  ? 198 GLN A N   1 
ATOM   7857  C  CA  . GLN E 1 216 ? 7.235   -72.545 20.241 1   51.72  ? 198 GLN A CA  1 
ATOM   7858  C  C   . GLN E 1 216 ? 7.575   -72.192 18.789 1   48.1   ? 198 GLN A C   1 
ATOM   7859  O  O   . GLN E 1 216 ? 8.414   -72.889 18.195 1   49.05  ? 198 GLN A O   1 
ATOM   7860  C  CB  . GLN E 1 216 ? 8.319   -72.014 21.184 1   53.41  ? 198 GLN A CB  1 
ATOM   7861  C  CG  . GLN E 1 216 ? 8.058   -72.293 22.659 1   52.78  ? 198 GLN A CG  1 
ATOM   7862  C  CD  . GLN E 1 216 ? 6.885   -71.513 23.204 1   54.59  ? 198 GLN A CD  1 
ATOM   7863  O  OE1 . GLN E 1 216 ? 6.735   -70.322 22.94  1   57.72  ? 198 GLN A OE1 1 
ATOM   7864  N  NE2 . GLN E 1 216 ? 6.036   -72.178 23.973 1   55.9   ? 198 GLN A NE2 1 
ATOM   7865  N  N   . THR E 1 217 ? 6.937   -71.153 18.248 1   44.9   ? 199 THR A N   1 
ATOM   7866  C  CA  . THR E 1 217 ? 7.259   -70.544 16.932 1   43.12  ? 199 THR A CA  1 
ATOM   7867  C  C   . THR E 1 217 ? 8.289   -69.439 17.174 1   44.19  ? 199 THR A C   1 
ATOM   7868  O  O   . THR E 1 217 ? 8.047   -68.588 18.056 1   44.58  ? 199 THR A O   1 
ATOM   7869  C  CB  . THR E 1 217 ? 6.007   -70.004 16.226 1   43.3   ? 199 THR A CB  1 
ATOM   7870  O  OG1 . THR E 1 217 ? 5.128   -71.097 15.961 1   44.68  ? 199 THR A OG1 1 
ATOM   7871  C  CG2 . THR E 1 217 ? 6.306   -69.288 14.925 1   43.82  ? 199 THR A CG2 1 
ATOM   7872  N  N   . TYR E 1 218 ? 9.393   -69.471 16.424 1   44.02  ? 200 TYR A N   1 
ATOM   7873  C  CA  . TYR E 1 218 ? 10.471  -68.451 16.434 1   41.87  ? 200 TYR A CA  1 
ATOM   7874  C  C   . TYR E 1 218 ? 10.603  -67.903 15.017 1   39.77  ? 200 TYR A C   1 
ATOM   7875  O  O   . TYR E 1 218 ? 11.002  -68.669 14.131 1   36.93  ? 200 TYR A O   1 
ATOM   7876  C  CB  . TYR E 1 218 ? 11.777  -69.052 16.959 1   42.52  ? 200 TYR A CB  1 
ATOM   7877  C  CG  . TYR E 1 218 ? 11.674  -69.596 18.362 1   42.66  ? 200 TYR A CG  1 
ATOM   7878  C  CD1 . TYR E 1 218 ? 11.443  -68.755 19.44  1   42.54  ? 200 TYR A CD1 1 
ATOM   7879  C  CD2 . TYR E 1 218 ? 11.796  -70.952 18.616 1   43.46  ? 200 TYR A CD2 1 
ATOM   7880  C  CE1 . TYR E 1 218 ? 11.332  -69.244 20.733 1   42.87  ? 200 TYR A CE1 1 
ATOM   7881  C  CE2 . TYR E 1 218 ? 11.692  -71.458 19.904 1   44.25  ? 200 TYR A CE2 1 
ATOM   7882  C  CZ  . TYR E 1 218 ? 11.456  -70.603 20.967 1   43.08  ? 200 TYR A CZ  1 
ATOM   7883  O  OH  . TYR E 1 218 ? 11.363  -71.116 22.23  1   42.43  ? 200 TYR A OH  1 
ATOM   7884  N  N   . ILE E 1 219 ? 10.23   -66.633 14.827 1   40.75  ? 201 ILE A N   1 
ATOM   7885  C  CA  . ILE E 1 219 ? 10.317  -65.903 13.528 1   41.09  ? 201 ILE A CA  1 
ATOM   7886  C  C   . ILE E 1 219 ? 11.215  -64.683 13.73  1   41.96  ? 201 ILE A C   1 
ATOM   7887  O  O   . ILE E 1 219 ? 10.915  -63.877 14.629 1   45     ? 201 ILE A O   1 
ATOM   7888  C  CB  . ILE E 1 219 ? 8.917   -65.517 13.009 1   39.67  ? 201 ILE A CB  1 
ATOM   7889  C  CG1 . ILE E 1 219 ? 8.078   -66.758 12.694 1   41.06  ? 201 ILE A CG1 1 
ATOM   7890  C  CG2 . ILE E 1 219 ? 9.015   -64.594 11.8   1   38.34  ? 201 ILE A CG2 1 
ATOM   7891  C  CD1 . ILE E 1 219 ? 6.596   -66.485 12.555 1   42.58  ? 201 ILE A CD1 1 
ATOM   7892  N  N   . CYS E 1 220 ? 12.266  -64.556 12.919 1   43.9   ? 202 CYS A N   1 
ATOM   7893  C  CA  . CYS E 1 220 ? 13.103  -63.333 12.842 1   44.43  ? 202 CYS A CA  1 
ATOM   7894  C  C   . CYS E 1 220 ? 12.485  -62.387 11.809 1   42.72  ? 202 CYS A C   1 
ATOM   7895  O  O   . CYS E 1 220 ? 12.029  -62.874 10.756 1   41.53  ? 202 CYS A O   1 
ATOM   7896  C  CB  . CYS E 1 220 ? 14.558  -63.647 12.52  1   46.95  ? 202 CYS A CB  1 
ATOM   7897  S  SG  . CYS E 1 220 ? 14.871  -64.047 10.783 1   51.23  ? 202 CYS A SG  1 
ATOM   7898  N  N   . ASN E 1 221 ? 12.472  -61.091 12.131 1   42.15  ? 203 ASN A N   1 
ATOM   7899  C  CA  . ASN E 1 221 ? 11.904  -59.992 11.31  1   41.19  ? 203 ASN A CA  1 
ATOM   7900  C  C   . ASN E 1 221 ? 13.082  -59.125 10.866 1   41.47  ? 203 ASN A C   1 
ATOM   7901  O  O   . ASN E 1 221 ? 13.571  -58.311 11.676 1   41.17  ? 203 ASN A O   1 
ATOM   7902  C  CB  . ASN E 1 221 ? 10.831  -59.21  12.076 1   41.16  ? 203 ASN A CB  1 
ATOM   7903  C  CG  . ASN E 1 221 ? 10.081  -60.073 13.068 1   41.63  ? 203 ASN A CG  1 
ATOM   7904  O  OD1 . ASN E 1 221 ? 10.327  -60.006 14.274 1   40.97  ? 203 ASN A OD1 1 
ATOM   7905  N  ND2 . ASN E 1 221 ? 9.209   -60.928 12.561 1   41.9   ? 203 ASN A ND2 1 
ATOM   7906  N  N   . VAL E 1 222 ? 13.56   -59.353 9.644  1   42.61  ? 204 VAL A N   1 
ATOM   7907  C  CA  . VAL E 1 222 ? 14.756  -58.672 9.074  1   43.92  ? 204 VAL A CA  1 
ATOM   7908  C  C   . VAL E 1 222 ? 14.253  -57.459 8.294  1   44.85  ? 204 VAL A C   1 
ATOM   7909  O  O   . VAL E 1 222 ? 13.406  -57.639 7.408  1   46.67  ? 204 VAL A O   1 
ATOM   7910  C  CB  . VAL E 1 222 ? 15.59   -59.625 8.194  1   43.14  ? 204 VAL A CB  1 
ATOM   7911  C  CG1 . VAL E 1 222 ? 16.881  -58.975 7.713  1   42.84  ? 204 VAL A CG1 1 
ATOM   7912  C  CG2 . VAL E 1 222 ? 15.895  -60.928 8.916  1   43.41  ? 204 VAL A CG2 1 
ATOM   7913  N  N   . ASN E 1 223 ? 14.739  -56.273 8.646  1   46.83  ? 205 ASN A N   1 
ATOM   7914  C  CA  . ASN E 1 223 ? 14.459  -55.007 7.929  1   49.79  ? 205 ASN A CA  1 
ATOM   7915  C  C   . ASN E 1 223 ? 15.788  -54.485 7.377  1   49.73  ? 205 ASN A C   1 
ATOM   7916  O  O   . ASN E 1 223 ? 16.746  -54.349 8.164  1   49.38  ? 205 ASN A O   1 
ATOM   7917  C  CB  . ASN E 1 223 ? 13.778  -53.986 8.844  1   53.36  ? 205 ASN A CB  1 
ATOM   7918  C  CG  . ASN E 1 223 ? 13.06   -52.879 8.102  1   57.76  ? 205 ASN A CG  1 
ATOM   7919  O  OD1 . ASN E 1 223 ? 13.206  -52.722 6.89   1   62.3   ? 205 ASN A OD1 1 
ATOM   7920  N  ND2 . ASN E 1 223 ? 12.273  -52.101 8.826  1   62.12  ? 205 ASN A ND2 1 
ATOM   7921  N  N   . HIS E 1 224 ? 15.842  -54.261 6.065  1   49.51  ? 206 HIS A N   1 
ATOM   7922  C  CA  . HIS E 1 224 ? 16.902  -53.495 5.363  1   48.8   ? 206 HIS A CA  1 
ATOM   7923  C  C   . HIS E 1 224 ? 16.218  -52.327 4.65   1   50.25  ? 206 HIS A C   1 
ATOM   7924  O  O   . HIS E 1 224 ? 15.782  -52.514 3.504  1   48.84  ? 206 HIS A O   1 
ATOM   7925  C  CB  . HIS E 1 224 ? 17.693  -54.427 4.436  1   46.87  ? 206 HIS A CB  1 
ATOM   7926  C  CG  . HIS E 1 224 ? 18.855  -53.773 3.77   1   45.41  ? 206 HIS A CG  1 
ATOM   7927  N  ND1 . HIS E 1 224 ? 18.942  -53.649 2.401  1   45.81  ? 206 HIS A ND1 1 
ATOM   7928  C  CD2 . HIS E 1 224 ? 19.976  -53.217 4.273  1   44.33  ? 206 HIS A CD2 1 
ATOM   7929  C  CE1 . HIS E 1 224 ? 20.071  -53.048 2.086  1   45.58  ? 206 HIS A CE1 1 
ATOM   7930  N  NE2 . HIS E 1 224 ? 20.723  -52.774 3.217  1   44.41  ? 206 HIS A NE2 1 
ATOM   7931  N  N   . LYS E 1 225 ? 16.084  -51.187 5.334  1   56.02  ? 207 LYS A N   1 
ATOM   7932  C  CA  . LYS E 1 225 ? 15.318  -50.004 4.843  1   62.23  ? 207 LYS A CA  1 
ATOM   7933  C  C   . LYS E 1 225 ? 15.909  -49.486 3.529  1   62.29  ? 207 LYS A C   1 
ATOM   7934  O  O   . LYS E 1 225 ? 15.144  -49.187 2.613  1   62.71  ? 207 LYS A O   1 
ATOM   7935  C  CB  . LYS E 1 225 ? 15.235  -48.912 5.916  1   65.6   ? 207 LYS A CB  1 
ATOM   7936  C  CG  . LYS E 1 225 ? 14.218  -49.184 7.018  1   68.66  ? 207 LYS A CG  1 
ATOM   7937  C  CD  . LYS E 1 225 ? 14.482  -48.407 8.291  1   71.44  ? 207 LYS A CD  1 
ATOM   7938  C  CE  . LYS E 1 225 ? 13.502  -48.729 9.398  1   72.87  ? 207 LYS A CE  1 
ATOM   7939  N  NZ  . LYS E 1 225 ? 13.983  -48.229 10.708 1   74.71  ? 207 LYS A NZ  1 
ATOM   7940  N  N   . PRO E 1 226 ? 17.254  -49.377 3.371  1   60.96  ? 208 PRO A N   1 
ATOM   7941  C  CA  . PRO E 1 226 ? 17.852  -48.885 2.126  1   58.83  ? 208 PRO A CA  1 
ATOM   7942  C  C   . PRO E 1 226 ? 17.46   -49.609 0.829  1   59.41  ? 208 PRO A C   1 
ATOM   7943  O  O   . PRO E 1 226 ? 17.552  -48.972 -0.198 1   60.66  ? 208 PRO A O   1 
ATOM   7944  C  CB  . PRO E 1 226 ? 19.352  -49.098 2.348  1   59.14  ? 208 PRO A CB  1 
ATOM   7945  C  CG  . PRO E 1 226 ? 19.509  -48.968 3.838  1   61.02  ? 208 PRO A CG  1 
ATOM   7946  C  CD  . PRO E 1 226 ? 18.281  -49.656 4.391  1   61.28  ? 208 PRO A CD  1 
ATOM   7947  N  N   . SER E 1 227 ? 17.068  -50.889 0.904  1   60.1   ? 209 SER A N   1 
ATOM   7948  C  CA  . SER E 1 227 ? 16.623  -51.722 -0.248 1   60.81  ? 209 SER A CA  1 
ATOM   7949  C  C   . SER E 1 227 ? 15.11   -51.985 -0.203 1   63.27  ? 209 SER A C   1 
ATOM   7950  O  O   . SER E 1 227 ? 14.633  -52.753 -1.07  1   62.4   ? 209 SER A O   1 
ATOM   7951  C  CB  . SER E 1 227 ? 17.39   -53.021 -0.296 1   61.5   ? 209 SER A CB  1 
ATOM   7952  O  OG  . SER E 1 227 ? 16.912  -53.941 0.679  1   60.6   ? 209 SER A OG  1 
ATOM   7953  N  N   . ASN E 1 228 ? 14.391  -51.385 0.759  1   66.4   ? 210 ASN A N   1 
ATOM   7954  C  CA  . ASN E 1 228 ? 12.955  -51.652 1.064  1   69.66  ? 210 ASN A CA  1 
ATOM   7955  C  C   . ASN E 1 228 ? 12.7    -53.172 1.081  1   66.93  ? 210 ASN A C   1 
ATOM   7956  O  O   . ASN E 1 228 ? 11.689  -53.618 0.504  1   69.76  ? 210 ASN A O   1 
ATOM   7957  C  CB  . ASN E 1 228 ? 12.041  -50.859 0.117  1   73.61  ? 210 ASN A CB  1 
ATOM   7958  C  CG  . ASN E 1 228 ? 11.377  -49.676 0.795  1   76.82  ? 210 ASN A CG  1 
ATOM   7959  O  OD1 . ASN E 1 228 ? 10.44   -49.853 1.574  1   80.21  ? 210 ASN A OD1 1 
ATOM   7960  N  ND2 . ASN E 1 228 ? 11.846  -48.468 0.514  1   76.45  ? 210 ASN A ND2 1 
ATOM   7961  N  N   . THR E 1 229 ? 13.595  -53.934 1.724  1   63.15  ? 211 THR A N   1 
ATOM   7962  C  CA  . THR E 1 229 ? 13.488  -55.401 1.944  1   60.75  ? 211 THR A CA  1 
ATOM   7963  C  C   . THR E 1 229 ? 13.083  -55.631 3.403  1   58.8   ? 211 THR A C   1 
ATOM   7964  O  O   . THR E 1 229 ? 13.913  -55.352 4.292  1   56.38  ? 211 THR A O   1 
ATOM   7965  C  CB  . THR E 1 229 ? 14.799  -56.124 1.603  1   60.89  ? 211 THR A CB  1 
ATOM   7966  O  OG1 . THR E 1 229 ? 15.149  -55.827 0.252  1   61.6   ? 211 THR A OG1 1 
ATOM   7967  C  CG2 . THR E 1 229 ? 14.714  -57.626 1.763  1   62     ? 211 THR A CG2 1 
ATOM   7968  N  N   . LYS E 1 230 ? 11.839  -56.067 3.622  1   58.34  ? 212 LYS A N   1 
ATOM   7969  C  CA  . LYS E 1 230 ? 11.329  -56.609 4.91   1   59.23  ? 212 LYS A CA  1 
ATOM   7970  C  C   . LYS E 1 230 ? 11.056  -58.102 4.706  1   57.44  ? 212 LYS A C   1 
ATOM   7971  O  O   . LYS E 1 230 ? 10.252  -58.426 3.814  1   62.23  ? 212 LYS A O   1 
ATOM   7972  C  CB  . LYS E 1 230 ? 10.053  -55.886 5.356  1   61.61  ? 212 LYS A CB  1 
ATOM   7973  C  CG  . LYS E 1 230 ? 10.235  -54.437 5.794  1   63.01  ? 212 LYS A CG  1 
ATOM   7974  C  CD  . LYS E 1 230 ? 9.078   -53.902 6.624  1   63.67  ? 212 LYS A CD  1 
ATOM   7975  C  CE  . LYS E 1 230 ? 9.149   -52.413 6.855  0   63.91  ? 212 LYS A CE  1 
ATOM   7976  N  NZ  . LYS E 1 230 ? 7.989   -51.92  7.635  0   63.95  ? 212 LYS A NZ  1 
ATOM   7977  N  N   . VAL E 1 231 ? 11.716  -58.969 5.479  1   53.68  ? 213 VAL A N   1 
ATOM   7978  C  CA  . VAL E 1 231 ? 11.569  -60.453 5.386  1   50.94  ? 213 VAL A CA  1 
ATOM   7979  C  C   . VAL E 1 231 ? 11.227  -60.992 6.776  1   49.77  ? 213 VAL A C   1 
ATOM   7980  O  O   . VAL E 1 231 ? 11.899  -60.602 7.742  1   53.92  ? 213 VAL A O   1 
ATOM   7981  C  CB  . VAL E 1 231 ? 12.833  -61.124 4.813  1   49.35  ? 213 VAL A CB  1 
ATOM   7982  C  CG1 . VAL E 1 231 ? 12.651  -62.624 4.636  1   50.56  ? 213 VAL A CG1 1 
ATOM   7983  C  CG2 . VAL E 1 231 ? 13.259  -60.499 3.496  1   49.77  ? 213 VAL A CG2 1 
ATOM   7984  N  N   . ASP E 1 232 ? 10.204  -61.841 6.856  1   49.49  ? 214 ASP A N   1 
ATOM   7985  C  CA  . ASP E 1 232 ? 9.891   -62.689 8.034  1   50.98  ? 214 ASP A CA  1 
ATOM   7986  C  C   . ASP E 1 232 ? 10.347  -64.106 7.688  1   51.96  ? 214 ASP A C   1 
ATOM   7987  O  O   . ASP E 1 232 ? 9.878   -64.613 6.655  1   56.82  ? 214 ASP A O   1 
ATOM   7988  C  CB  . ASP E 1 232 ? 8.393   -62.683 8.36   1   53.45  ? 214 ASP A CB  1 
ATOM   7989  C  CG  . ASP E 1 232 ? 7.87    -61.452 9.087  1   54.01  ? 214 ASP A CG  1 
ATOM   7990  O  OD1 . ASP E 1 232 ? 8.634   -60.469 9.256  1   50.62  ? 214 ASP A OD1 1 
ATOM   7991  O  OD2 . ASP E 1 232 ? 6.691   -61.494 9.495  1   59.79  ? 214 ASP A OD2 1 
ATOM   7992  N  N   . LYS E 1 233 ? 11.241  -64.701 8.485  1   50.8   ? 215 LYS A N   1 
ATOM   7993  C  CA  . LYS E 1 233 ? 11.729  -66.092 8.286  1   47.94  ? 215 LYS A CA  1 
ATOM   7994  C  C   . LYS E 1 233 ? 11.477  -66.892 9.566  1   44.94  ? 215 LYS A C   1 
ATOM   7995  O  O   . LYS E 1 233 ? 12.041  -66.528 10.609 1   42.54  ? 215 LYS A O   1 
ATOM   7996  C  CB  . LYS E 1 233 ? 13.212  -66.119 7.905  1   49.58  ? 215 LYS A CB  1 
ATOM   7997  C  CG  . LYS E 1 233 ? 13.74   -67.476 7.45   1   51.48  ? 215 LYS A CG  1 
ATOM   7998  C  CD  . LYS E 1 233 ? 13.8    -67.644 5.947  1   54.3   ? 215 LYS A CD  1 
ATOM   7999  C  CE  . LYS E 1 233 ? 12.455  -67.532 5.265  1   58.88  ? 215 LYS A CE  1 
ATOM   8000  N  NZ  . LYS E 1 233 ? 12.536  -67.922 3.837  1   61.56  ? 215 LYS A NZ  1 
ATOM   8001  N  N   . LYS E 1 234 ? 10.65   -67.935 9.467  1   44.94  ? 216 LYS A N   1 
ATOM   8002  C  CA  . LYS E 1 234 ? 10.375  -68.904 10.556 1   46.13  ? 216 LYS A CA  1 
ATOM   8003  C  C   . LYS E 1 234 ? 11.576  -69.844 10.644 1   45.39  ? 216 LYS A C   1 
ATOM   8004  O  O   . LYS E 1 234 ? 12.022  -70.315 9.581  1   47.22  ? 216 LYS A O   1 
ATOM   8005  C  CB  . LYS E 1 234 ? 9.079   -69.669 10.272 1   50.15  ? 216 LYS A CB  1 
ATOM   8006  C  CG  . LYS E 1 234 ? 8.645   -70.65  11.355 1   55.63  ? 216 LYS A CG  1 
ATOM   8007  C  CD  . LYS E 1 234 ? 7.428   -71.478 10.986 1   59.31  ? 216 LYS A CD  1 
ATOM   8008  C  CE  . LYS E 1 234 ? 7.066   -72.477 12.064 1   62.6   ? 216 LYS A CE  1 
ATOM   8009  N  NZ  . LYS E 1 234 ? 6.157   -73.53  11.554 1   65.8   ? 216 LYS A NZ  1 
ATOM   8010  N  N   . VAL E 1 235 ? 12.066  -70.098 11.86  1   45.46  ? 217 VAL A N   1 
ATOM   8011  C  CA  . VAL E 1 235 ? 13.254  -70.955 12.145 1   46.87  ? 217 VAL A CA  1 
ATOM   8012  C  C   . VAL E 1 235 ? 12.769  -72.219 12.865 1   49.54  ? 217 VAL A C   1 
ATOM   8013  O  O   . VAL E 1 235 ? 12.59   -72.171 14.099 1   49.19  ? 217 VAL A O   1 
ATOM   8014  C  CB  . VAL E 1 235 ? 14.305  -70.176 12.956 1   46.27  ? 217 VAL A CB  1 
ATOM   8015  C  CG1 . VAL E 1 235 ? 15.579  -70.979 13.173 1   47.29  ? 217 VAL A CG1 1 
ATOM   8016  C  CG2 . VAL E 1 235 ? 14.625  -68.845 12.3   1   47     ? 217 VAL A CG2 1 
ATOM   8017  N  N   . GLU E 1 236 ? 12.552  -73.295 12.103 1   53.44  ? 218 GLU A N   1 
ATOM   8018  C  CA  . GLU E 1 236 ? 12.077  -74.617 12.594 1   57.37  ? 218 GLU A CA  1 
ATOM   8019  C  C   . GLU E 1 236 ? 13.273  -75.508 12.916 1   59.81  ? 218 GLU A C   1 
ATOM   8020  O  O   . GLU E 1 236 ? 14.365  -75.284 12.401 1   55.88  ? 218 GLU A O   1 
ATOM   8021  C  CB  . GLU E 1 236 ? 11.227  -75.315 11.53  1   61.77  ? 218 GLU A CB  1 
ATOM   8022  C  CG  . GLU E 1 236 ? 9.862   -74.688 11.31  1   66.19  ? 218 GLU A CG  1 
ATOM   8023  C  CD  . GLU E 1 236 ? 9.084   -75.28  10.147 1   69.82  ? 218 GLU A CD  1 
ATOM   8024  O  OE1 . GLU E 1 236 ? 9.409   -76.408 9.726  1   72.88  ? 218 GLU A OE1 1 
ATOM   8025  O  OE2 . GLU E 1 236 ? 8.159   -74.607 9.657  1   76.7   ? 218 GLU A OE2 1 
ATOM   8026  N  N   . PRO E 1 237 ? 13.097  -76.579 13.729 1   65.09  ? 219 PRO A N   1 
ATOM   8027  C  CA  . PRO E 1 237 ? 14.14   -77.593 13.902 1   65.09  ? 219 PRO A CA  1 
ATOM   8028  C  C   . PRO E 1 237 ? 14.417  -78.365 12.603 1   65.81  ? 219 PRO A C   1 
ATOM   8029  O  O   . PRO E 1 237 ? 13.599  -78.314 11.706 1   62.19  ? 219 PRO A O   1 
ATOM   8030  C  CB  . PRO E 1 237 ? 13.572  -78.522 14.985 1   66.22  ? 219 PRO A CB  1 
ATOM   8031  C  CG  . PRO E 1 237 ? 12.077  -78.344 14.867 1   67.37  ? 219 PRO A CG  1 
ATOM   8032  C  CD  . PRO E 1 237 ? 11.895  -76.881 14.524 1   65.82  ? 219 PRO A CD  1 
ATOM   8033  N  N   . LYS E 1 238 ? 15.549  -79.074 12.555 1   72.08  ? 220 LYS A N   1 
ATOM   8034  C  CA  . LYS E 1 238 ? 16.084  -79.75  11.339 1   78     ? 220 LYS A CA  1 
ATOM   8035  C  C   . LYS E 1 238 ? 15.17   -80.924 10.956 1   79.38  ? 220 LYS A C   1 
ATOM   8036  O  O   . LYS E 1 238 ? 14.47   -81.447 11.84  1   74.5   ? 220 LYS A O   1 
ATOM   8037  C  CB  . LYS E 1 238 ? 17.532  -80.19  11.587 1   83.17  ? 220 LYS A CB  1 
ATOM   8038  C  CG  . LYS E 1 238 ? 18.509  -79.05  11.866 1   88.4   ? 220 LYS A CG  1 
ATOM   8039  C  CD  . LYS E 1 238 ? 19.924  -79.486 12.223 1   92.25  ? 220 LYS A CD  1 
ATOM   8040  C  CE  . LYS E 1 238 ? 20.709  -80.076 11.067 1   96.35  ? 220 LYS A CE  1 
ATOM   8041  N  NZ  . LYS E 1 238 ? 20.989  -79.091 9.992  1   96.17  ? 220 LYS A NZ  1 
ATOM   8042  N  N   . SER E 1 239 ? 15.172  -81.312 9.675  1   87.23  ? 221 SER A N   1 
ATOM   8043  C  CA  . SER E 1 239 ? 14.35   -82.418 9.103  1   92.66  ? 221 SER A CA  1 
ATOM   8044  C  C   . SER E 1 239 ? 14.754  -83.778 9.695  1   97.64  ? 221 SER A C   1 
ATOM   8045  O  O   . SER E 1 239 ? 13.908  -84.694 9.671  1   101.17 ? 221 SER A O   1 
ATOM   8046  C  CB  . SER E 1 239 ? 14.427  -82.448 7.594  1   92.71  ? 221 SER A CB  1 
ATOM   8047  O  OG  . SER E 1 239 ? 13.684  -81.38  7.027  1   95.17  ? 221 SER A OG  1 
ATOM   8048  N  N   . CYS E 1 240 ? 15.988  -83.907 10.199 1   102.76 ? 222 CYS A N   1 
ATOM   8049  C  CA  . CYS E 1 240 ? 16.524  -85.127 10.868 1   107    ? 222 CYS A CA  1 
ATOM   8050  C  C   . CYS E 1 240 ? 16.156  -85.168 12.366 1   107.53 ? 222 CYS A C   1 
ATOM   8051  O  O   . CYS E 1 240 ? 16.577  -86.134 13.036 1   105.12 ? 222 CYS A O   1 
ATOM   8052  C  CB  . CYS E 1 240 ? 18.037  -85.209 10.683 1   108.46 ? 222 CYS A CB  1 
ATOM   8053  S  SG  . CYS E 1 240 ? 18.961  -83.874 11.493 1   107.65 ? 222 CYS A SG  1 
ATOM   8054  N  N   . ASP E 1 241 ? 15.395  -84.184 12.872 1   110.63 ? 223 ASP A N   1 
ATOM   8055  C  CA  . ASP E 1 241 ? 15.046  -84.011 14.311 1   111.22 ? 223 ASP A CA  1 
ATOM   8056  C  C   . ASP E 1 241 ? 13.781  -84.817 14.644 1   112.06 ? 223 ASP A C   1 
ATOM   8057  O  O   . ASP E 1 241 ? 12.853  -84.841 13.805 1   110.87 ? 223 ASP A O   1 
ATOM   8058  C  CB  . ASP E 1 241 ? 14.858  -82.526 14.643 1   112.05 ? 223 ASP A CB  1 
ATOM   8059  C  CG  . ASP E 1 241 ? 14.908  -82.175 16.121 1   113.55 ? 223 ASP A CG  1 
ATOM   8060  O  OD1 . ASP E 1 241 ? 14.25   -82.87  16.92  1   116.45 ? 223 ASP A OD1 1 
ATOM   8061  O  OD2 . ASP E 1 241 ? 15.594  -81.19  16.459 1   116.79 ? 223 ASP A OD2 1 
ATOM   8062  N  N   . LYS E 1 242 ? 13.755  -85.436 15.833 1   110.21 ? 224 LYS A N   1 
ATOM   8063  C  CA  . LYS E 1 242 ? 12.581  -86.135 16.427 1   106.58 ? 224 LYS A CA  1 
ATOM   8064  C  C   . LYS E 1 242 ? 12.428  -85.703 17.892 1   102.21 ? 224 LYS A C   1 
ATOM   8065  O  O   . LYS E 1 242 ? 13.378  -85.742 18.677 1   94.5   ? 224 LYS A O   1 
ATOM   8066  C  CB  . LYS E 1 242 ? 12.743  -87.656 16.317 1   107.77 ? 224 LYS A CB  1 
ATOM   8067  C  CG  . LYS E 1 242 ? 12.404  -88.25  14.955 1   107.29 ? 224 LYS A CG  1 
ATOM   8068  C  CD  . LYS E 1 242 ? 12.268  -89.764 15.001 0   111.24 ? 224 LYS A CD  1 
ATOM   8069  C  CE  . LYS E 1 242 ? 11.765  -90.351 13.7   0   111.22 ? 224 LYS A CE  1 
ATOM   8070  N  NZ  . LYS E 1 242 ? 11.718  -91.831 13.75  0   111.17 ? 224 LYS A NZ  1 
ATOM   8071  N  N   . SER F 2 21  ? 36.489  -25.939 14.964 1   90.57  ? 2   SER B N   1 
ATOM   8072  C  CA  . SER F 2 21  ? 37.406  -26.753 15.835 1   90.6   ? 2   SER B CA  1 
ATOM   8073  C  C   . SER F 2 21  ? 36.586  -27.722 16.705 1   90.36  ? 2   SER B C   1 
ATOM   8074  O  O   . SER F 2 21  ? 35.373  -27.891 16.434 1   91.77  ? 2   SER B O   1 
ATOM   8075  C  CB  . SER F 2 21  ? 38.31   -25.859 16.667 1   89.65  ? 2   SER B CB  1 
ATOM   8076  O  OG  . SER F 2 21  ? 37.629  -25.359 17.811 1   88.7   ? 2   SER B OG  1 
ATOM   8077  N  N   . VAL F 2 22  ? 37.234  -28.351 17.693 1   83.83  ? 3   VAL B N   1 
ATOM   8078  C  CA  . VAL F 2 22  ? 36.644  -29.369 18.616 1   76.43  ? 3   VAL B CA  1 
ATOM   8079  C  C   . VAL F 2 22  ? 37.191  -29.1   20.028 1   69.98  ? 3   VAL B C   1 
ATOM   8080  O  O   . VAL F 2 22  ? 38.418  -28.896 20.143 1   72.8   ? 3   VAL B O   1 
ATOM   8081  C  CB  . VAL F 2 22  ? 36.977  -30.786 18.1   1   75.73  ? 3   VAL B CB  1 
ATOM   8082  C  CG1 . VAL F 2 22  ? 36.708  -31.884 19.119 1   76.36  ? 3   VAL B CG1 1 
ATOM   8083  C  CG2 . VAL F 2 22  ? 36.247  -31.093 16.799 1   75.9   ? 3   VAL B CG2 1 
ATOM   8084  N  N   . LEU F 2 23  ? 36.329  -29.085 21.055 1   61.06  ? 4   LEU B N   1 
ATOM   8085  C  CA  . LEU F 2 23  ? 36.749  -29.001 22.487 1   56.31  ? 4   LEU B CA  1 
ATOM   8086  C  C   . LEU F 2 23  ? 37.684  -30.18  22.765 1   52.83  ? 4   LEU B C   1 
ATOM   8087  O  O   . LEU F 2 23  ? 37.397  -31.276 22.267 1   51.98  ? 4   LEU B O   1 
ATOM   8088  C  CB  . LEU F 2 23  ? 35.539  -29.055 23.428 1   54.2   ? 4   LEU B CB  1 
ATOM   8089  C  CG  . LEU F 2 23  ? 34.531  -27.914 23.319 1   55.49  ? 4   LEU B CG  1 
ATOM   8090  C  CD1 . LEU F 2 23  ? 33.277  -28.235 24.12  1   57.28  ? 4   LEU B CD1 1 
ATOM   8091  C  CD2 . LEU F 2 23  ? 35.131  -26.596 23.783 1   56.92  ? 4   LEU B CD2 1 
ATOM   8092  N  N   . THR F 2 24  ? 38.772  -29.969 23.504 1   50.23  ? 5   THR B N   1 
ATOM   8093  C  CA  . THR F 2 24  ? 39.882  -30.954 23.599 1   48.79  ? 5   THR B CA  1 
ATOM   8094  C  C   . THR F 2 24  ? 39.666  -31.845 24.823 1   46.17  ? 5   THR B C   1 
ATOM   8095  O  O   . THR F 2 24  ? 39.718  -31.314 25.945 1   47.11  ? 5   THR B O   1 
ATOM   8096  C  CB  . THR F 2 24  ? 41.243  -30.256 23.571 1   48.46  ? 5   THR B CB  1 
ATOM   8097  O  OG1 . THR F 2 24  ? 41.183  -29.288 22.524 1   48.46  ? 5   THR B OG1 1 
ATOM   8098  C  CG2 . THR F 2 24  ? 42.382  -31.22  23.319 1   49.31  ? 5   THR B CG2 1 
ATOM   8099  N  N   . GLN F 2 25  ? 39.411  -33.139 24.581 1   44.37  ? 6   GLN B N   1 
ATOM   8100  C  CA  . GLN F 2 25  ? 39.271  -34.215 25.599 1   43.83  ? 6   GLN B CA  1 
ATOM   8101  C  C   . GLN F 2 25  ? 40.412  -35.218 25.443 1   42.73  ? 6   GLN B C   1 
ATOM   8102  O  O   . GLN F 2 25  ? 40.931  -35.4   24.345 1   41.29  ? 6   GLN B O   1 
ATOM   8103  C  CB  . GLN F 2 25  ? 37.962  -34.985 25.42  1   43.05  ? 6   GLN B CB  1 
ATOM   8104  C  CG  . GLN F 2 25  ? 36.711  -34.223 25.83  1   44.28  ? 6   GLN B CG  1 
ATOM   8105  C  CD  . GLN F 2 25  ? 35.458  -35.06  25.699 1   45.47  ? 6   GLN B CD  1 
ATOM   8106  O  OE1 . GLN F 2 25  ? 34.496  -34.665 25.045 1   46.36  ? 6   GLN B OE1 1 
ATOM   8107  N  NE2 . GLN F 2 25  ? 35.449  -36.23  26.321 1   44.9   ? 6   GLN B NE2 1 
ATOM   8108  N  N   . PRO F 2 26  ? 40.811  -35.94  26.516 1   42.97  ? 7   PRO B N   1 
ATOM   8109  C  CA  . PRO F 2 26  ? 41.771  -37.034 26.377 1   43.43  ? 7   PRO B CA  1 
ATOM   8110  C  C   . PRO F 2 26  ? 41.118  -38.206 25.647 1   43.37  ? 7   PRO B C   1 
ATOM   8111  O  O   . PRO F 2 26  ? 40.006  -38.592 25.99  1   44.17  ? 7   PRO B O   1 
ATOM   8112  C  CB  . PRO F 2 26  ? 42.134  -37.384 27.827 1   42.73  ? 7   PRO B CB  1 
ATOM   8113  C  CG  . PRO F 2 26  ? 40.916  -36.977 28.623 1   43.38  ? 7   PRO B CG  1 
ATOM   8114  C  CD  . PRO F 2 26  ? 40.364  -35.761 27.907 1   43.2   ? 7   PRO B CD  1 
ATOM   8115  N  N   . PRO F 2 27  ? 41.766  -38.803 24.619 1   44.3   ? 8   PRO B N   1 
ATOM   8116  C  CA  . PRO F 2 27  ? 41.174  -39.924 23.891 1   43.82  ? 8   PRO B CA  1 
ATOM   8117  C  C   . PRO F 2 27  ? 40.749  -41.095 24.794 1   43.07  ? 8   PRO B C   1 
ATOM   8118  O  O   . PRO F 2 27  ? 39.848  -41.817 24.405 1   45.23  ? 8   PRO B O   1 
ATOM   8119  C  CB  . PRO F 2 27  ? 42.242  -40.392 22.884 1   43.54  ? 8   PRO B CB  1 
ATOM   8120  C  CG  . PRO F 2 27  ? 43.378  -39.383 22.958 1   44.06  ? 8   PRO B CG  1 
ATOM   8121  C  CD  . PRO F 2 27  ? 43.08   -38.416 24.087 1   44.96  ? 8   PRO B CD  1 
ATOM   8122  N  N   . SER F 2 28  ? 41.384  -41.267 25.957 1   41.75  ? 9   SER B N   1 
ATOM   8123  C  CA  . SER F 2 28  ? 41.016  -42.328 26.931 1   42.28  ? 9   SER B CA  1 
ATOM   8124  C  C   . SER F 2 28  ? 41.424  -41.946 28.358 1   40.88  ? 9   SER B C   1 
ATOM   8125  O  O   . SER F 2 28  ? 42.434  -41.246 28.508 1   44.63  ? 9   SER B O   1 
ATOM   8126  C  CB  . SER F 2 28  ? 41.63   -43.643 26.534 1   42.44  ? 9   SER B CB  1 
ATOM   8127  O  OG  . SER F 2 28  ? 43.034  -43.633 26.733 1   40.89  ? 9   SER B OG  1 
ATOM   8128  N  N   . VAL F 2 29  ? 40.636  -42.374 29.349 1   38.74  ? 10  VAL B N   1 
ATOM   8129  C  CA  . VAL F 2 29  ? 41.035  -42.456 30.785 1   38.68  ? 10  VAL B CA  1 
ATOM   8130  C  C   . VAL F 2 29  ? 40.712  -43.876 31.254 1   38.4   ? 10  VAL B C   1 
ATOM   8131  O  O   . VAL F 2 29  ? 39.881  -44.54  30.612 1   37.75  ? 10  VAL B O   1 
ATOM   8132  C  CB  . VAL F 2 29  ? 40.377  -41.383 31.686 1   39.3   ? 10  VAL B CB  1 
ATOM   8133  C  CG1 . VAL F 2 29  ? 40.311  -40.009 31.028 1   38.73  ? 10  VAL B CG1 1 
ATOM   8134  C  CG2 . VAL F 2 29  ? 39.004  -41.787 32.189 1   40.17  ? 10  VAL B CG2 1 
ATOM   8135  N  N   . SER F 2 30  ? 41.373  -44.328 32.317 1   39.76  ? 11  SER B N   1 
ATOM   8136  C  CA  . SER F 2 30  ? 41.155  -45.661 32.935 1   39.23  ? 11  SER B CA  1 
ATOM   8137  C  C   . SER F 2 30  ? 41.224  -45.537 34.455 1   38.14  ? 11  SER B C   1 
ATOM   8138  O  O   . SER F 2 30  ? 41.793  -44.539 34.95  1   37.6   ? 11  SER B O   1 
ATOM   8139  C  CB  . SER F 2 30  ? 42.125  -46.694 32.411 1   39.5   ? 11  SER B CB  1 
ATOM   8140  O  OG  . SER F 2 30  ? 43.469  -46.338 32.693 1   39.78  ? 11  SER B OG  1 
ATOM   8141  N  N   . GLY F 2 31  ? 40.641  -46.514 35.148 1   38     ? 12  GLY B N   1 
ATOM   8142  C  CA  . GLY F 2 31  ? 40.565  -46.552 36.619 1   38.99  ? 12  GLY B CA  1 
ATOM   8143  C  C   . GLY F 2 31  ? 40.32   -47.957 37.135 1   39.62  ? 12  GLY B C   1 
ATOM   8144  O  O   . GLY F 2 31  ? 39.864  -48.811 36.348 1   38.01  ? 12  GLY B O   1 
ATOM   8145  N  N   . ALA F 2 32  ? 40.652  -48.186 38.406 1   40.22  ? 13  ALA B N   1 
ATOM   8146  C  CA  . ALA F 2 32  ? 40.311  -49.409 39.163 1   43.19  ? 13  ALA B CA  1 
ATOM   8147  C  C   . ALA F 2 32  ? 38.882  -49.273 39.682 1   43.59  ? 13  ALA B C   1 
ATOM   8148  O  O   . ALA F 2 32  ? 38.413  -48.159 39.9   1   43.5   ? 13  ALA B O   1 
ATOM   8149  C  CB  . ALA F 2 32  ? 41.294  -49.601 40.292 1   45.87  ? 13  ALA B CB  1 
ATOM   8150  N  N   . PRO F 2 33  ? 38.138  -50.385 39.888 1   43.55  ? 14  PRO B N   1 
ATOM   8151  C  CA  . PRO F 2 33  ? 36.828  -50.326 40.545 1   44.85  ? 14  PRO B CA  1 
ATOM   8152  C  C   . PRO F 2 33  ? 36.875  -49.57  41.885 1   45.96  ? 14  PRO B C   1 
ATOM   8153  O  O   . PRO F 2 33  ? 37.833  -49.739 42.618 1   49.14  ? 14  PRO B O   1 
ATOM   8154  C  CB  . PRO F 2 33  ? 36.453  -51.8   40.769 1   44.3   ? 14  PRO B CB  1 
ATOM   8155  C  CG  . PRO F 2 33  ? 37.237  -52.557 39.711 1   44     ? 14  PRO B CG  1 
ATOM   8156  C  CD  . PRO F 2 33  ? 38.494  -51.745 39.467 1   43.34  ? 14  PRO B CD  1 
ATOM   8157  N  N   . GLY F 2 34  ? 35.876  -48.723 42.146 1   45.58  ? 15  GLY B N   1 
ATOM   8158  C  CA  . GLY F 2 34  ? 35.76   -47.937 43.39  1   45.45  ? 15  GLY B CA  1 
ATOM   8159  C  C   . GLY F 2 34  ? 36.579  -46.655 43.359 1   45.9   ? 15  GLY B C   1 
ATOM   8160  O  O   . GLY F 2 34  ? 36.433  -45.858 44.303 1   47.37  ? 15  GLY B O   1 
ATOM   8161  N  N   . GLN F 2 35  ? 37.398  -46.45  42.319 1   45.03  ? 16  GLN B N   1 
ATOM   8162  C  CA  . GLN F 2 35  ? 38.289  -45.273 42.145 1   45.34  ? 16  GLN B CA  1 
ATOM   8163  C  C   . GLN F 2 35  ? 37.442  -44.048 41.788 1   44.45  ? 16  GLN B C   1 
ATOM   8164  O  O   . GLN F 2 35  ? 36.325  -44.24  41.274 1   44.59  ? 16  GLN B O   1 
ATOM   8165  C  CB  . GLN F 2 35  ? 39.314  -45.571 41.045 1   48.92  ? 16  GLN B CB  1 
ATOM   8166  C  CG  . GLN F 2 35  ? 40.366  -44.491 40.836 1   51.37  ? 16  GLN B CG  1 
ATOM   8167  C  CD  . GLN F 2 35  ? 41.432  -44.889 39.842 1   52.11  ? 16  GLN B CD  1 
ATOM   8168  O  OE1 . GLN F 2 35  ? 41.868  -46.039 39.79  1   54.14  ? 16  GLN B OE1 1 
ATOM   8169  N  NE2 . GLN F 2 35  ? 41.881  -43.927 39.051 1   53.15  ? 16  GLN B NE2 1 
ATOM   8170  N  N   . ARG F 2 36  ? 37.95   -42.845 42.084 1   44.01  ? 17  ARG B N   1 
ATOM   8171  C  CA  . ARG F 2 36  ? 37.488  -41.561 41.49  1   43.43  ? 17  ARG B CA  1 
ATOM   8172  C  C   . ARG F 2 36  ? 38.362  -41.293 40.266 1   42.74  ? 17  ARG B C   1 
ATOM   8173  O  O   . ARG F 2 36  ? 39.591  -41.326 40.42  1   44.13  ? 17  ARG B O   1 
ATOM   8174  C  CB  . ARG F 2 36  ? 37.565  -40.384 42.474 1   42.61  ? 17  ARG B CB  1 
ATOM   8175  C  CG  . ARG F 2 36  ? 37.346  -39.013 41.839 1   42.59  ? 17  ARG B CG  1 
ATOM   8176  C  CD  . ARG F 2 36  ? 37.314  -37.873 42.842 1   43.69  ? 17  ARG B CD  1 
ATOM   8177  N  NE  . ARG F 2 36  ? 36.98   -36.58  42.243 1   45.01  ? 17  ARG B NE  1 
ATOM   8178  C  CZ  . ARG F 2 36  ? 37.812  -35.791 41.546 1   46.02  ? 17  ARG B CZ  1 
ATOM   8179  N  NH1 . ARG F 2 36  ? 39.068  -36.145 41.322 1   47.38  ? 17  ARG B NH1 1 
ATOM   8180  N  NH2 . ARG F 2 36  ? 37.376  -34.639 41.057 1   44.89  ? 17  ARG B NH2 1 
ATOM   8181  N  N   . VAL F 2 37  ? 37.745  -41.035 39.112 1   43.7   ? 18  VAL B N   1 
ATOM   8182  C  CA  . VAL F 2 37  ? 38.444  -40.686 37.839 1   44.96  ? 18  VAL B CA  1 
ATOM   8183  C  C   . VAL F 2 37  ? 37.853  -39.372 37.317 1   45.11  ? 18  VAL B C   1 
ATOM   8184  O  O   . VAL F 2 37  ? 36.679  -39.095 37.634 1   46.11  ? 18  VAL B O   1 
ATOM   8185  C  CB  . VAL F 2 37  ? 38.325  -41.838 36.825 1   46.6   ? 18  VAL B CB  1 
ATOM   8186  C  CG1 . VAL F 2 37  ? 36.937  -41.937 36.206 1   46.14  ? 18  VAL B CG1 1 
ATOM   8187  C  CG2 . VAL F 2 37  ? 39.391  -41.748 35.751 1   49.64  ? 18  VAL B CG2 1 
ATOM   8188  N  N   . THR F 2 38  ? 38.634  -38.591 36.568 1   44.63  ? 19  THR B N   1 
ATOM   8189  C  CA  . THR F 2 38  ? 38.198  -37.297 35.974 1   44.75  ? 19  THR B CA  1 
ATOM   8190  C  C   . THR F 2 38  ? 38.446  -37.308 34.463 1   44.63  ? 19  THR B C   1 
ATOM   8191  O  O   . THR F 2 38  ? 39.466  -37.891 34.041 1   48.2   ? 19  THR B O   1 
ATOM   8192  C  CB  . THR F 2 38  ? 38.9    -36.106 36.637 1   44.55  ? 19  THR B CB  1 
ATOM   8193  O  OG1 . THR F 2 38  ? 40.305  -36.28  36.465 1   45.53  ? 19  THR B OG1 1 
ATOM   8194  C  CG2 . THR F 2 38  ? 38.565  -35.967 38.106 1   43.58  ? 19  THR B CG2 1 
ATOM   8195  N  N   . ILE F 2 39  ? 37.538  -36.692 33.696 1   43.44  ? 20  ILE B N   1 
ATOM   8196  C  CA  . ILE F 2 39  ? 37.67   -36.47  32.224 1   43.41  ? 20  ILE B CA  1 
ATOM   8197  C  C   . ILE F 2 39  ? 37.618  -34.96  31.98  1   43.55  ? 20  ILE B C   1 
ATOM   8198  O  O   . ILE F 2 39  ? 36.582  -34.362 32.299 1   43.66  ? 20  ILE B O   1 
ATOM   8199  C  CB  . ILE F 2 39  ? 36.58   -37.23  31.439 1   42     ? 20  ILE B CB  1 
ATOM   8200  C  CG1 . ILE F 2 39  ? 36.613  -38.733 31.732 1   41.03  ? 20  ILE B CG1 1 
ATOM   8201  C  CG2 . ILE F 2 39  ? 36.699  -36.948 29.946 1   41.94  ? 20  ILE B CG2 1 
ATOM   8202  C  CD1 . ILE F 2 39  ? 35.378  -39.472 31.305 1   40.85  ? 20  ILE B CD1 1 
ATOM   8203  N  N   . SER F 2 40  ? 38.695  -34.387 31.433 1   43.96  ? 21  SER B N   1 
ATOM   8204  C  CA  . SER F 2 40  ? 38.865  -32.929 31.191 1   44.63  ? 21  SER B CA  1 
ATOM   8205  C  C   . SER F 2 40  ? 38.33   -32.558 29.805 1   43.9   ? 21  SER B C   1 
ATOM   8206  O  O   . SER F 2 40  ? 38.279  -33.435 28.921 1   40.25  ? 21  SER B O   1 
ATOM   8207  C  CB  . SER F 2 40  ? 40.307  -32.497 31.352 1   45.27  ? 21  SER B CB  1 
ATOM   8208  O  OG  . SER F 2 40  ? 41.128  -33.056 30.334 1   47.53  ? 21  SER B OG  1 
ATOM   8209  N  N   . CYS F 2 41  ? 37.959  -31.286 29.647 1   44.47  ? 22  CYS B N   1 
ATOM   8210  C  CA  . CYS F 2 41  ? 37.317  -30.704 28.441 1   45.56  ? 22  CYS B CA  1 
ATOM   8211  C  C   . CYS F 2 41  ? 37.815  -29.264 28.301 1   45.29  ? 22  CYS B C   1 
ATOM   8212  O  O   . CYS F 2 41  ? 37.317  -28.406 29.051 1   47.61  ? 22  CYS B O   1 
ATOM   8213  C  CB  . CYS F 2 41  ? 35.796  -30.774 28.564 1   46.8   ? 22  CYS B CB  1 
ATOM   8214  S  SG  . CYS F 2 41  ? 34.907  -30.134 27.12  1   50.39  ? 22  CYS B SG  1 
ATOM   8215  N  N   . ALA F 2 42  ? 38.804  -29.032 27.431 1   44.2   ? 23  ALA B N   1 
ATOM   8216  C  CA  . ALA F 2 42  ? 39.504  -27.734 27.274 1   43.91  ? 23  ALA B CA  1 
ATOM   8217  C  C   . ALA F 2 42  ? 38.892  -26.978 26.098 1   42.8   ? 23  ALA B C   1 
ATOM   8218  O  O   . ALA F 2 42  ? 38.985  -27.482 24.964 1   44.15  ? 23  ALA B O   1 
ATOM   8219  C  CB  . ALA F 2 42  ? 40.983  -27.945 27.074 1   44.64  ? 23  ALA B CB  1 
ATOM   8220  N  N   . GLY F 2 43  ? 38.29   -25.821 26.375 1   43.11  ? 24  GLY B N   1 
ATOM   8221  C  CA  . GLY F 2 43  ? 37.629  -24.962 25.376 1   45.18  ? 24  GLY B CA  1 
ATOM   8222  C  C   . GLY F 2 43  ? 38.269  -23.589 25.298 1   46.92  ? 24  GLY B C   1 
ATOM   8223  O  O   . GLY F 2 43  ? 39.475  -23.478 25.583 1   46.4   ? 24  GLY B O   1 
ATOM   8224  N  N   . THR F 2 44  ? 37.473  -22.583 24.929 1   50.02  ? 25  THR B N   1 
ATOM   8225  C  CA  . THR F 2 44  ? 37.906  -21.191 24.637 1   52.05  ? 25  THR B CA  1 
ATOM   8226  C  C   . THR F 2 44  ? 37.042  -20.211 25.441 1   56.1   ? 25  THR B C   1 
ATOM   8227  O  O   . THR F 2 44  ? 36.071  -20.656 26.099 1   54.94  ? 25  THR B O   1 
ATOM   8228  C  CB  . THR F 2 44  ? 37.833  -20.888 23.133 1   50.73  ? 25  THR B CB  1 
ATOM   8229  O  OG1 . THR F 2 44  ? 36.47   -20.702 22.754 1   52.38  ? 25  THR B OG1 1 
ATOM   8230  C  CG2 . THR F 2 44  ? 38.433  -21.974 22.266 1   50.43  ? 25  THR B CG2 1 
ATOM   8231  N  N   . SER F 2 45  ? 37.391  -18.924 25.364 1   60.88  ? 26  SER B N   1 
ATOM   8232  C  CA  . SER F 2 45  ? 36.657  -17.771 25.954 1   62.61  ? 26  SER B CA  1 
ATOM   8233  C  C   . SER F 2 45  ? 35.293  -17.583 25.275 1   61.99  ? 26  SER B C   1 
ATOM   8234  O  O   . SER F 2 45  ? 34.42   -16.951 25.894 1   61.04  ? 26  SER B O   1 
ATOM   8235  C  CB  . SER F 2 45  ? 37.48   -16.514 25.849 1   64.25  ? 26  SER B CB  1 
ATOM   8236  O  OG  . SER F 2 45  ? 37.913  -16.314 24.509 1   64.11  ? 26  SER B OG  1 
ATOM   8237  N  N   . SER F 2 46  ? 35.133  -18.079 24.042 1   61.74  ? 27  SER B N   1 
ATOM   8238  C  CA  . SER F 2 46  ? 33.877  -18.017 23.248 1   61.4   ? 27  SER B CA  1 
ATOM   8239  C  C   . SER F 2 46  ? 32.888  -19.128 23.648 1   59.63  ? 27  SER B C   1 
ATOM   8240  O  O   . SER F 2 46  ? 31.721  -19.021 23.217 1   62.81  ? 27  SER B O   1 
ATOM   8241  C  CB  . SER F 2 46  ? 34.18   -18.07  21.774 1   62.27  ? 27  SER B CB  1 
ATOM   8242  O  OG  . SER F 2 46  ? 34.632  -19.363 21.4   1   65.41  ? 27  SER B OG  1 
ATOM   8243  N  N   . ASP F 2 47  ? 33.308  -20.147 24.415 1   55.97  ? 28  ASP B N   1 
ATOM   8244  C  CA  . ASP F 2 47  ? 32.433  -21.28  24.841 1   53.91  ? 28  ASP B CA  1 
ATOM   8245  C  C   . ASP F 2 47  ? 32.507  -21.46  26.365 1   53.32  ? 28  ASP B C   1 
ATOM   8246  O  O   . ASP F 2 47  ? 31.739  -20.765 27.049 1   56.47  ? 28  ASP B O   1 
ATOM   8247  C  CB  . ASP F 2 47  ? 32.704  -22.558 24.034 1   51.74  ? 28  ASP B CB  1 
ATOM   8248  C  CG  . ASP F 2 47  ? 34.169  -22.87  23.791 1   51.49  ? 28  ASP B CG  1 
ATOM   8249  O  OD1 . ASP F 2 47  ? 34.858  -23.209 24.773 1   50.28  ? 28  ASP B OD1 1 
ATOM   8250  O  OD2 . ASP F 2 47  ? 34.611  -22.764 22.628 1   50     ? 28  ASP B OD2 1 
ATOM   8251  N  N   . ILE F 2 48  ? 33.37   -22.345 26.883 1   51.43  ? 29  ILE B N   1 
ATOM   8252  C  CA  . ILE F 2 48  ? 33.393  -22.752 28.324 1   50.95  ? 29  ILE B CA  1 
ATOM   8253  C  C   . ILE F 2 48  ? 33.774  -21.533 29.18  1   53.21  ? 29  ILE B C   1 
ATOM   8254  O  O   . ILE F 2 48  ? 33.195  -21.378 30.281 1   51.45  ? 29  ILE B O   1 
ATOM   8255  C  CB  . ILE F 2 48  ? 34.341  -23.951 28.563 1   48.69  ? 29  ILE B CB  1 
ATOM   8256  C  CG1 . ILE F 2 48  ? 33.909  -25.177 27.751 1   48.44  ? 29  ILE B CG1 1 
ATOM   8257  C  CG2 . ILE F 2 48  ? 34.455  -24.268 30.052 1   48.57  ? 29  ILE B CG2 1 
ATOM   8258  C  CD1 . ILE F 2 48  ? 34.8    -26.391 27.9   1   47.95  ? 29  ILE B CD1 1 
ATOM   8259  N  N   . GLY F 2 49  ? 34.725  -20.72  28.706 1   54.06  ? 30  GLY B N   1 
ATOM   8260  C  CA  . GLY F 2 49  ? 35.154  -19.473 29.368 1   57.87  ? 30  GLY B CA  1 
ATOM   8261  C  C   . GLY F 2 49  ? 34.058  -18.421 29.355 1   58.23  ? 30  GLY B C   1 
ATOM   8262  O  O   . GLY F 2 49  ? 33.612  -18.053 28.251 1   57.36  ? 30  GLY B O   1 
ATOM   8263  N  N   . GLY F 2 50  ? 33.61   -17.982 30.536 1   60.17  ? 31  GLY B N   1 
ATOM   8264  C  CA  . GLY F 2 50  ? 32.64   -16.88  30.694 1   65.15  ? 31  GLY B CA  1 
ATOM   8265  C  C   . GLY F 2 50  ? 31.189  -17.339 30.752 1   65.73  ? 31  GLY B C   1 
ATOM   8266  O  O   . GLY F 2 50  ? 30.391  -16.581 31.322 1   66.28  ? 31  GLY B O   1 
ATOM   8267  N  N   . ARG F 2 51  ? 30.848  -18.498 30.166 1   66.56  ? 32  ARG B N   1 
ATOM   8268  C  CA  . ARG F 2 51  ? 29.48   -19.093 30.176 1   66.07  ? 32  ARG B CA  1 
ATOM   8269  C  C   . ARG F 2 51  ? 29.468  -20.386 30.998 1   61.13  ? 32  ARG B C   1 
ATOM   8270  O  O   . ARG F 2 51  ? 30.549  -20.888 31.344 1   63.02  ? 32  ARG B O   1 
ATOM   8271  C  CB  . ARG F 2 51  ? 29      -19.381 28.751 1   69.96  ? 32  ARG B CB  1 
ATOM   8272  C  CG  . ARG F 2 51  ? 28.418  -18.174 28.029 1   75.08  ? 32  ARG B CG  1 
ATOM   8273  C  CD  . ARG F 2 51  ? 29.033  -17.997 26.658 1   79.74  ? 32  ARG B CD  1 
ATOM   8274  N  NE  . ARG F 2 51  ? 28.261  -17.128 25.781 1   84.64  ? 32  ARG B NE  1 
ATOM   8275  C  CZ  . ARG F 2 51  ? 28.672  -16.696 24.589 1   91.1   ? 32  ARG B CZ  1 
ATOM   8276  N  NH1 . ARG F 2 51  ? 29.864  -17.039 24.123 1   92.83  ? 32  ARG B NH1 1 
ATOM   8277  N  NH2 . ARG F 2 51  ? 27.887  -15.917 23.862 1   94.09  ? 32  ARG B NH2 1 
ATOM   8278  N  N   . THR F 2 52  ? 28.264  -20.891 31.277 1   56.57  ? 33  THR B N   1 
ATOM   8279  C  CA  . THR F 2 52  ? 27.989  -22.101 32.092 1   53.35  ? 33  THR B CA  1 
ATOM   8280  C  C   . THR F 2 52  ? 27.157  -23.102 31.275 1   52.76  ? 33  THR B C   1 
ATOM   8281  O  O   . THR F 2 52  ? 26.42   -23.887 31.9   1   55.13  ? 33  THR B O   1 
ATOM   8282  C  CB  . THR F 2 52  ? 27.287  -21.691 33.395 1   53.14  ? 33  THR B CB  1 
ATOM   8283  O  OG1 . THR F 2 52  ? 26.129  -20.933 33.042 1   53.93  ? 33  THR B OG1 1 
ATOM   8284  C  CG2 . THR F 2 52  ? 28.171  -20.876 34.312 1   52.45  ? 33  THR B CG2 1 
ATOM   8285  N  N   . TYR F 2 53  ? 27.281  -23.108 29.939 1   49.9   ? 34  TYR B N   1 
ATOM   8286  C  CA  . TYR F 2 53  ? 26.467  -23.957 29.024 1   47.02  ? 34  TYR B CA  1 
ATOM   8287  C  C   . TYR F 2 53  ? 27.293  -25.168 28.574 1   46.46  ? 34  TYR B C   1 
ATOM   8288  O  O   . TYR F 2 53  ? 27.394  -25.43  27.361 1   48.54  ? 34  TYR B O   1 
ATOM   8289  C  CB  . TYR F 2 53  ? 25.924  -23.128 27.854 1   46.18  ? 34  TYR B CB  1 
ATOM   8290  C  CG  . TYR F 2 53  ? 24.935  -22.061 28.252 1   44.71  ? 34  TYR B CG  1 
ATOM   8291  C  CD1 . TYR F 2 53  ? 23.808  -22.377 28.998 1   42.96  ? 34  TYR B CD1 1 
ATOM   8292  C  CD2 . TYR F 2 53  ? 25.116  -20.737 27.881 1   43.23  ? 34  TYR B CD2 1 
ATOM   8293  C  CE1 . TYR F 2 53  ? 22.893  -21.407 29.373 1   42.89  ? 34  TYR B CE1 1 
ATOM   8294  C  CE2 . TYR F 2 53  ? 24.209  -19.756 28.249 1   42.37  ? 34  TYR B CE2 1 
ATOM   8295  C  CZ  . TYR F 2 53  ? 23.095  -20.09  29.001 1   42.24  ? 34  TYR B CZ  1 
ATOM   8296  O  OH  . TYR F 2 53  ? 22.193  -19.131 29.361 1   40.21  ? 34  TYR B OH  1 
ATOM   8297  N  N   . VAL F 2 54  ? 27.831  -25.909 29.544 1   43.5   ? 35  VAL B N   1 
ATOM   8298  C  CA  . VAL F 2 54  ? 28.68   -27.115 29.33  1   42.57  ? 35  VAL B CA  1 
ATOM   8299  C  C   . VAL F 2 54  ? 27.852  -28.338 29.728 1   42.34  ? 35  VAL B C   1 
ATOM   8300  O  O   . VAL F 2 54  ? 27.369  -28.373 30.876 1   44.94  ? 35  VAL B O   1 
ATOM   8301  C  CB  . VAL F 2 54  ? 29.986  -27.018 30.138 1   42.74  ? 35  VAL B CB  1 
ATOM   8302  C  CG1 . VAL F 2 54  ? 30.887  -28.23  29.936 1   43.37  ? 35  VAL B CG1 1 
ATOM   8303  C  CG2 . VAL F 2 54  ? 30.734  -25.741 29.807 1   42.95  ? 35  VAL B CG2 1 
ATOM   8304  N  N   . SER F 2 55  ? 27.696  -29.291 28.809 1   40.96  ? 36  SER B N   1 
ATOM   8305  C  CA  . SER F 2 55  ? 26.895  -30.528 28.992 1   41.91  ? 36  SER B CA  1 
ATOM   8306  C  C   . SER F 2 55  ? 27.813  -31.744 28.828 1   40.38  ? 36  SER B C   1 
ATOM   8307  O  O   . SER F 2 55  ? 28.806  -31.632 28.089 1   39.36  ? 36  SER B O   1 
ATOM   8308  C  CB  . SER F 2 55  ? 25.735  -30.584 28.021 1   43.85  ? 36  SER B CB  1 
ATOM   8309  O  OG  . SER F 2 55  ? 25.484  -29.314 27.427 1   50.11  ? 36  SER B OG  1 
ATOM   8310  N  N   . TRP F 2 56  ? 27.471  -32.855 29.483 1   39.11  ? 37  TRP B N   1 
ATOM   8311  C  CA  . TRP F 2 56  ? 28.179  -34.158 29.4   1   39.9   ? 37  TRP B CA  1 
ATOM   8312  C  C   . TRP F 2 56  ? 27.206  -35.245 28.938 1   39.58  ? 37  TRP B C   1 
ATOM   8313  O  O   . TRP F 2 56  ? 26.069  -35.282 29.461 1   38.75  ? 37  TRP B O   1 
ATOM   8314  C  CB  . TRP F 2 56  ? 28.818  -34.502 30.749 1   42.13  ? 37  TRP B CB  1 
ATOM   8315  C  CG  . TRP F 2 56  ? 30.031  -33.673 31.035 1   43.78  ? 37  TRP B CG  1 
ATOM   8316  C  CD1 . TRP F 2 56  ? 30.087  -32.506 31.739 1   43.25  ? 37  TRP B CD1 1 
ATOM   8317  C  CD2 . TRP F 2 56  ? 31.366  -33.927 30.567 1   44.3   ? 37  TRP B CD2 1 
ATOM   8318  N  NE1 . TRP F 2 56  ? 31.367  -32.026 31.755 1   43.98  ? 37  TRP B NE1 1 
ATOM   8319  C  CE2 . TRP F 2 56  ? 32.175  -32.875 31.047 1   44.72  ? 37  TRP B CE2 1 
ATOM   8320  C  CE3 . TRP F 2 56  ? 31.959  -34.944 29.81  1   45.54  ? 37  TRP B CE3 1 
ATOM   8321  C  CZ2 . TRP F 2 56  ? 33.548  -32.82  30.796 1   46.94  ? 37  TRP B CZ2 1 
ATOM   8322  C  CZ3 . TRP F 2 56  ? 33.315  -34.889 29.562 1   46.67  ? 37  TRP B CZ3 1 
ATOM   8323  C  CH2 . TRP F 2 56  ? 34.098  -33.842 30.053 1   46.95  ? 37  TRP B CH2 1 
ATOM   8324  N  N   . TYR F 2 57  ? 27.646  -36.094 28.004 1   39.52  ? 38  TYR B N   1 
ATOM   8325  C  CA  . TYR F 2 57  ? 26.861  -37.221 27.435 1   38.91  ? 38  TYR B CA  1 
ATOM   8326  C  C   . TYR F 2 57  ? 27.626  -38.526 27.65  1   39.67  ? 38  TYR B C   1 
ATOM   8327  O  O   . TYR F 2 57  ? 28.86   -38.524 27.467 1   39.8   ? 38  TYR B O   1 
ATOM   8328  C  CB  . TYR F 2 57  ? 26.546  -36.969 25.959 1   37.75  ? 38  TYR B CB  1 
ATOM   8329  C  CG  . TYR F 2 57  ? 25.87   -35.643 25.746 1   39.05  ? 38  TYR B CG  1 
ATOM   8330  C  CD1 . TYR F 2 57  ? 24.499  -35.507 25.896 1   38.91  ? 38  TYR B CD1 1 
ATOM   8331  C  CD2 . TYR F 2 57  ? 26.613  -34.503 25.482 1   39.94  ? 38  TYR B CD2 1 
ATOM   8332  C  CE1 . TYR F 2 57  ? 23.88   -34.276 25.746 1   39.07  ? 38  TYR B CE1 1 
ATOM   8333  C  CE2 . TYR F 2 57  ? 26.007  -33.266 25.329 1   39.27  ? 38  TYR B CE2 1 
ATOM   8334  C  CZ  . TYR F 2 57  ? 24.636  -33.151 25.464 1   39.15  ? 38  TYR B CZ  1 
ATOM   8335  O  OH  . TYR F 2 57  ? 24.038  -31.934 25.307 1   41.82  ? 38  TYR B OH  1 
ATOM   8336  N  N   . GLN F 2 58  ? 26.909  -39.578 28.061 1   39.99  ? 39  GLN B N   1 
ATOM   8337  C  CA  . GLN F 2 58  ? 27.384  -40.987 28.083 1   40.22  ? 39  GLN B CA  1 
ATOM   8338  C  C   . GLN F 2 58  ? 26.871  -41.676 26.819 1   39.84  ? 39  GLN B C   1 
ATOM   8339  O  O   . GLN F 2 58  ? 25.66   -41.555 26.549 1   39.12  ? 39  GLN B O   1 
ATOM   8340  C  CB  . GLN F 2 58  ? 26.866  -41.719 29.322 1   40.18  ? 39  GLN B CB  1 
ATOM   8341  C  CG  . GLN F 2 58  ? 27.432  -43.121 29.491 1   40.61  ? 39  GLN B CG  1 
ATOM   8342  C  CD  . GLN F 2 58  ? 26.774  -43.842 30.642 1   41.16  ? 39  GLN B CD  1 
ATOM   8343  O  OE1 . GLN F 2 58  ? 25.619  -44.25  30.556 1   43.75  ? 39  GLN B OE1 1 
ATOM   8344  N  NE2 . GLN F 2 58  ? 27.5    -44.007 31.737 1   42.25  ? 39  GLN B NE2 1 
ATOM   8345  N  N   . GLN F 2 59  ? 27.753  -42.361 26.083 1   39.95  ? 40  GLN B N   1 
ATOM   8346  C  CA  . GLN F 2 59  ? 27.377  -43.223 24.929 1   41.12  ? 40  GLN B CA  1 
ATOM   8347  C  C   . GLN F 2 59  ? 27.881  -44.647 25.182 1   43.9   ? 40  GLN B C   1 
ATOM   8348  O  O   . GLN F 2 59  ? 29.081  -44.908 24.956 1   46.31  ? 40  GLN B O   1 
ATOM   8349  C  CB  . GLN F 2 59  ? 27.922  -42.68  23.608 1   39.59  ? 40  GLN B CB  1 
ATOM   8350  C  CG  . GLN F 2 59  ? 27.411  -43.465 22.408 1   38.98  ? 40  GLN B CG  1 
ATOM   8351  C  CD  . GLN F 2 59  ? 27.649  -42.778 21.087 1   36.79  ? 40  GLN B CD  1 
ATOM   8352  O  OE1 . GLN F 2 59  ? 28.665  -42.119 20.885 1   37.36  ? 40  GLN B OE1 1 
ATOM   8353  N  NE2 . GLN F 2 59  ? 26.714  -42.939 20.166 1   36.42  ? 40  GLN B NE2 1 
ATOM   8354  N  N   . LEU F 2 60  ? 26.992  -45.537 25.625 1   47.61  ? 41  LEU B N   1 
ATOM   8355  C  CA  . LEU F 2 60  ? 27.27   -46.997 25.697 1   49.95  ? 41  LEU B CA  1 
ATOM   8356  C  C   . LEU F 2 60  ? 27.404  -47.498 24.262 1   51.86  ? 41  LEU B C   1 
ATOM   8357  O  O   . LEU F 2 60  ? 26.916  -46.841 23.344 1   49.31  ? 41  LEU B O   1 
ATOM   8358  C  CB  . LEU F 2 60  ? 26.138  -47.704 26.452 1   48.61  ? 41  LEU B CB  1 
ATOM   8359  C  CG  . LEU F 2 60  ? 25.944  -47.277 27.907 1   49.03  ? 41  LEU B CG  1 
ATOM   8360  C  CD1 . LEU F 2 60  ? 24.606  -47.758 28.445 1   49     ? 41  LEU B CD1 1 
ATOM   8361  C  CD2 . LEU F 2 60  ? 27.077  -47.783 28.779 1   50.05  ? 41  LEU B CD2 1 
ATOM   8362  N  N   . PRO F 2 61  ? 28.082  -48.641 24.006 1   57.74  ? 42  PRO B N   1 
ATOM   8363  C  CA  . PRO F 2 61  ? 28.217  -49.155 22.64  1   58.37  ? 42  PRO B CA  1 
ATOM   8364  C  C   . PRO F 2 61  ? 26.845  -49.502 22.039 1   56.48  ? 42  PRO B C   1 
ATOM   8365  O  O   . PRO F 2 61  ? 25.987  -49.96  22.778 1   52.24  ? 42  PRO B O   1 
ATOM   8366  C  CB  . PRO F 2 61  ? 29.095  -50.403 22.805 1   62.32  ? 42  PRO B CB  1 
ATOM   8367  C  CG  . PRO F 2 61  ? 28.86   -50.82  24.245 1   65.09  ? 42  PRO B CG  1 
ATOM   8368  C  CD  . PRO F 2 61  ? 28.735  -49.511 24.997 1   62.46  ? 42  PRO B CD  1 
ATOM   8369  N  N   . GLY F 2 62  ? 26.656  -49.212 20.747 1   57.13  ? 43  GLY B N   1 
ATOM   8370  C  CA  . GLY F 2 62  ? 25.398  -49.447 20.01  1   59.03  ? 43  GLY B CA  1 
ATOM   8371  C  C   . GLY F 2 62  ? 24.417  -48.291 20.136 1   60.93  ? 43  GLY B C   1 
ATOM   8372  O  O   . GLY F 2 62  ? 23.953  -47.799 19.085 1   68.87  ? 43  GLY B O   1 
ATOM   8373  N  N   . THR F 2 63  ? 24.118  -47.867 21.37  1   57.2   ? 44  THR B N   1 
ATOM   8374  C  CA  . THR F 2 63  ? 23.023  -46.927 21.739 1   52.25  ? 44  THR B CA  1 
ATOM   8375  C  C   . THR F 2 63  ? 23.394  -45.466 21.445 1   47.62  ? 44  THR B C   1 
ATOM   8376  O  O   . THR F 2 63  ? 24.589  -45.15  21.366 1   45.75  ? 44  THR B O   1 
ATOM   8377  C  CB  . THR F 2 63  ? 22.678  -47.084 23.224 1   54.67  ? 44  THR B CB  1 
ATOM   8378  O  OG1 . THR F 2 63  ? 23.896  -46.964 23.961 1   53.91  ? 44  THR B OG1 1 
ATOM   8379  C  CG2 . THR F 2 63  ? 22.022  -48.41  23.541 1   56.83  ? 44  THR B CG2 1 
ATOM   8380  N  N   . ALA F 2 64  ? 22.379  -44.604 21.335 1   46.07  ? 45  ALA B N   1 
ATOM   8381  C  CA  . ALA F 2 64  ? 22.495  -43.133 21.171 1   43.28  ? 45  ALA B CA  1 
ATOM   8382  C  C   . ALA F 2 64  ? 23.028  -42.495 22.456 1   42.23  ? 45  ALA B C   1 
ATOM   8383  O  O   . ALA F 2 64  ? 22.91   -43.084 23.531 1   40.7   ? 45  ALA B O   1 
ATOM   8384  C  CB  . ALA F 2 64  ? 21.155  -42.55  20.807 1   42.41  ? 45  ALA B CB  1 
ATOM   8385  N  N   . PRO F 2 65  ? 23.606  -41.267 22.402 1   40.29  ? 46  PRO B N   1 
ATOM   8386  C  CA  . PRO F 2 65  ? 24.123  -40.606 23.6   1   40     ? 46  PRO B CA  1 
ATOM   8387  C  C   . PRO F 2 65  ? 23.012  -40.232 24.594 1   39.23  ? 46  PRO B C   1 
ATOM   8388  O  O   . PRO F 2 65  ? 21.89   -40.011 24.183 1   40.44  ? 46  PRO B O   1 
ATOM   8389  C  CB  . PRO F 2 65  ? 24.824  -39.335 23.089 1   40.15  ? 46  PRO B CB  1 
ATOM   8390  C  CG  . PRO F 2 65  ? 24.961  -39.541 21.595 1   40.47  ? 46  PRO B CG  1 
ATOM   8391  C  CD  . PRO F 2 65  ? 23.803  -40.437 21.203 1   40.56  ? 46  PRO B CD  1 
ATOM   8392  N  N   . LYS F 2 66  ? 23.365  -40.198 25.878 1   39.53  ? 47  LYS B N   1 
ATOM   8393  C  CA  . LYS F 2 66  ? 22.466  -39.88  27.013 1   41.22  ? 47  LYS B CA  1 
ATOM   8394  C  C   . LYS F 2 66  ? 23.097  -38.725 27.794 1   40.43  ? 47  LYS B C   1 
ATOM   8395  O  O   . LYS F 2 66  ? 24.259  -38.875 28.206 1   42.59  ? 47  LYS B O   1 
ATOM   8396  C  CB  . LYS F 2 66  ? 22.27   -41.134 27.873 1   44.68  ? 47  LYS B CB  1 
ATOM   8397  C  CG  . LYS F 2 66  ? 21.924  -40.898 29.34  1   48.41  ? 47  LYS B CG  1 
ATOM   8398  C  CD  . LYS F 2 66  ? 21.633  -42.171 30.104 1   52.4   ? 47  LYS B CD  1 
ATOM   8399  C  CE  . LYS F 2 66  ? 20.96   -41.909 31.436 1   56.78  ? 47  LYS B CE  1 
ATOM   8400  N  NZ  . LYS F 2 66  ? 20.575  -43.166 32.12  1   58.98  ? 47  LYS B NZ  1 
ATOM   8401  N  N   . LEU F 2 67  ? 22.36   -37.629 27.985 1   39.08  ? 48  LEU B N   1 
ATOM   8402  C  CA  . LEU F 2 67  ? 22.764  -36.485 28.846 1   39.43  ? 48  LEU B CA  1 
ATOM   8403  C  C   . LEU F 2 67  ? 22.969  -36.982 30.282 1   39.36  ? 48  LEU B C   1 
ATOM   8404  O  O   . LEU F 2 67  ? 22.036  -37.604 30.808 1   39.77  ? 48  LEU B O   1 
ATOM   8405  C  CB  . LEU F 2 67  ? 21.668  -35.418 28.791 1   39.2   ? 48  LEU B CB  1 
ATOM   8406  C  CG  . LEU F 2 67  ? 21.955  -34.114 29.533 1   39.35  ? 48  LEU B CG  1 
ATOM   8407  C  CD1 . LEU F 2 67  ? 22.893  -33.224 28.735 1   38.65  ? 48  LEU B CD1 1 
ATOM   8408  C  CD2 . LEU F 2 67  ? 20.66   -33.38  29.823 1   40.27  ? 48  LEU B CD2 1 
ATOM   8409  N  N   . LEU F 2 68  ? 24.153  -36.737 30.861 1   40.15  ? 49  LEU B N   1 
ATOM   8410  C  CA  . LEU F 2 68  ? 24.461  -36.94  32.303 1   41.27  ? 49  LEU B CA  1 
ATOM   8411  C  C   . LEU F 2 68  ? 24.322  -35.599 33.026 1   43.04  ? 49  LEU B C   1 
ATOM   8412  O  O   . LEU F 2 68  ? 23.476  -35.504 33.931 1   45.21  ? 49  LEU B O   1 
ATOM   8413  C  CB  . LEU F 2 68  ? 25.886  -37.467 32.49  1   42.67  ? 49  LEU B CB  1 
ATOM   8414  C  CG  . LEU F 2 68  ? 26.194  -38.845 31.914 1   45.31  ? 49  LEU B CG  1 
ATOM   8415  C  CD1 . LEU F 2 68  ? 27.687  -39.106 31.998 1   47.65  ? 49  LEU B CD1 1 
ATOM   8416  C  CD2 . LEU F 2 68  ? 25.42   -39.942 32.63  1   44.65  ? 49  LEU B CD2 1 
ATOM   8417  N  N   . ILE F 2 69  ? 25.136  -34.614 32.628 1   42.88  ? 50  ILE B N   1 
ATOM   8418  C  CA  . ILE F 2 69  ? 25.28   -33.29  33.303 1   43.63  ? 50  ILE B CA  1 
ATOM   8419  C  C   . ILE F 2 69  ? 24.925  -32.196 32.295 1   44.07  ? 50  ILE B C   1 
ATOM   8420  O  O   . ILE F 2 69  ? 25.332  -32.315 31.129 1   44.3   ? 50  ILE B O   1 
ATOM   8421  C  CB  . ILE F 2 69  ? 26.704  -33.076 33.861 1   45.21  ? 50  ILE B CB  1 
ATOM   8422  C  CG1 . ILE F 2 69  ? 27.234  -34.278 34.655 1   43.92  ? 50  ILE B CG1 1 
ATOM   8423  C  CG2 . ILE F 2 69  ? 26.771  -31.797 34.684 1   45.56  ? 50  ILE B CG2 1 
ATOM   8424  C  CD1 . ILE F 2 69  ? 26.424  -34.636 35.875 1   43.24  ? 50  ILE B CD1 1 
ATOM   8425  N  N   . TYR F 2 70  ? 24.203  -31.17  32.743 1   45.82  ? 51  TYR B N   1 
ATOM   8426  C  CA  . TYR F 2 70  ? 23.965  -29.908 31.993 1   47.42  ? 51  TYR B CA  1 
ATOM   8427  C  C   . TYR F 2 70  ? 24.218  -28.735 32.944 1   48.44  ? 51  TYR B C   1 
ATOM   8428  O  O   . TYR F 2 70  ? 24.225  -28.955 34.172 1   49.14  ? 51  TYR B O   1 
ATOM   8429  C  CB  . TYR F 2 70  ? 22.567  -29.897 31.361 1   46.6   ? 51  TYR B CB  1 
ATOM   8430  C  CG  . TYR F 2 70  ? 21.404  -29.895 32.321 1   46.79  ? 51  TYR B CG  1 
ATOM   8431  C  CD1 . TYR F 2 70  ? 20.837  -31.08  32.767 1   46.17  ? 51  TYR B CD1 1 
ATOM   8432  C  CD2 . TYR F 2 70  ? 20.848  -28.703 32.768 1   48.04  ? 51  TYR B CD2 1 
ATOM   8433  C  CE1 . TYR F 2 70  ? 19.758  -31.081 33.642 1   47.03  ? 51  TYR B CE1 1 
ATOM   8434  C  CE2 . TYR F 2 70  ? 19.772  -28.687 33.645 1   46.98  ? 51  TYR B CE2 1 
ATOM   8435  C  CZ  . TYR F 2 70  ? 19.226  -29.88  34.084 1   46.59  ? 51  TYR B CZ  1 
ATOM   8436  O  OH  . TYR F 2 70  ? 18.168  -29.868 34.944 1   46.88  ? 51  TYR B OH  1 
ATOM   8437  N  N   . LYS F 2 71  ? 24.437  -27.54  32.385 1   51.67  ? 52  LYS B N   1 
ATOM   8438  C  CA  . LYS F 2 71  ? 24.685  -26.275 33.135 1   53.53  ? 52  LYS B CA  1 
ATOM   8439  C  C   . LYS F 2 71  ? 25.927  -26.449 34.021 1   52.44  ? 52  LYS B C   1 
ATOM   8440  O  O   . LYS F 2 71  ? 25.924  -25.934 35.159 1   56.05  ? 52  LYS B O   1 
ATOM   8441  C  CB  . LYS F 2 71  ? 23.436  -25.867 33.933 1   55.98  ? 52  LYS B CB  1 
ATOM   8442  C  CG  . LYS F 2 71  ? 22.696  -24.645 33.407 1   56.91  ? 52  LYS B CG  1 
ATOM   8443  C  CD  . LYS F 2 71  ? 23.433  -23.346 33.62  1   57.45  ? 52  LYS B CD  1 
ATOM   8444  C  CE  . LYS F 2 71  ? 22.52   -22.139 33.658 1   57.54  ? 52  LYS B CE  1 
ATOM   8445  N  NZ  . LYS F 2 71  ? 23.215  -20.959 34.224 1   58.14  ? 52  LYS B NZ  1 
ATOM   8446  N  N   . VAL F 2 72  ? 26.939  -27.17  33.526 1   50.88  ? 53  VAL B N   1 
ATOM   8447  C  CA  . VAL F 2 72  ? 28.233  -27.453 34.221 1   50.96  ? 53  VAL B CA  1 
ATOM   8448  C  C   . VAL F 2 72  ? 28.034  -28.491 35.336 1   50.45  ? 53  VAL B C   1 
ATOM   8449  O  O   . VAL F 2 72  ? 28.807  -29.46  35.333 1   53.63  ? 53  VAL B O   1 
ATOM   8450  C  CB  . VAL F 2 72  ? 28.903  -26.179 34.777 1   51.55  ? 53  VAL B CB  1 
ATOM   8451  C  CG1 . VAL F 2 72  ? 30.27   -26.476 35.372 1   53.02  ? 53  VAL B CG1 1 
ATOM   8452  C  CG2 . VAL F 2 72  ? 29.019  -25.083 33.726 1   51.27  ? 53  VAL B CG2 1 
ATOM   8453  N  N   . THR F 2 73  ? 27.089  -28.277 36.265 1   49.31  ? 54  THR B N   1 
ATOM   8454  C  CA  . THR F 2 73  ? 27.004  -28.975 37.583 1   48.26  ? 54  THR B CA  1 
ATOM   8455  C  C   . THR F 2 73  ? 25.749  -29.85  37.737 1   47.11  ? 54  THR B C   1 
ATOM   8456  O  O   . THR F 2 73  ? 25.764  -30.693 38.655 1   46.04  ? 54  THR B O   1 
ATOM   8457  C  CB  . THR F 2 73  ? 27.001  -27.963 38.736 1   49.36  ? 54  THR B CB  1 
ATOM   8458  O  OG1 . THR F 2 73  ? 25.854  -27.123 38.59  1   50.92  ? 54  THR B OG1 1 
ATOM   8459  C  CG2 . THR F 2 73  ? 28.257  -27.121 38.788 1   49.43  ? 54  THR B CG2 1 
ATOM   8460  N  N   . ILE F 2 74  ? 24.699  -29.659 36.926 1   46.53  ? 55  ILE B N   1 
ATOM   8461  C  CA  . ILE F 2 74  ? 23.344  -30.238 37.193 1   44.82  ? 55  ILE B CA  1 
ATOM   8462  C  C   . ILE F 2 74  ? 23.235  -31.627 36.546 1   44.66  ? 55  ILE B C   1 
ATOM   8463  O  O   . ILE F 2 74  ? 23.335  -31.713 35.315 1   44.61  ? 55  ILE B O   1 
ATOM   8464  C  CB  . ILE F 2 74  ? 22.208  -29.3   36.735 1   43.11  ? 55  ILE B CB  1 
ATOM   8465  C  CG1 . ILE F 2 74  ? 22.41   -27.869 37.248 1   42.84  ? 55  ILE B CG1 1 
ATOM   8466  C  CG2 . ILE F 2 74  ? 20.862  -29.875 37.161 1   43.47  ? 55  ILE B CG2 1 
ATOM   8467  C  CD1 . ILE F 2 74  ? 21.35   -26.88  36.815 1   42.74  ? 55  ILE B CD1 1 
ATOM   8468  N  N   . ARG F 2 75  ? 23.01   -32.657 37.366 1   44.9   ? 56  ARG B N   1 
ATOM   8469  C  CA  A ARG F 2 75  ? 22.733  -34.045 36.911 0.5 46.48  ? 56  ARG B CA  1 
ATOM   8470  C  CA  B ARG F 2 75  ? 22.735  -34.044 36.908 0.5 46.52  ? 56  ARG B CA  1 
ATOM   8471  C  C   . ARG F 2 75  ? 21.356  -34.089 36.244 1   48.1   ? 56  ARG B C   1 
ATOM   8472  O  O   . ARG F 2 75  ? 20.438  -33.448 36.773 1   49.76  ? 56  ARG B O   1 
ATOM   8473  C  CB  A ARG F 2 75  ? 22.74   -35.036 38.08  0.5 46.68  ? 56  ARG B CB  1 
ATOM   8474  C  CB  B ARG F 2 75  ? 22.762  -35.032 38.08  0.5 46.77  ? 56  ARG B CB  1 
ATOM   8475  C  CG  A ARG F 2 75  ? 24.118  -35.339 38.646 0.5 46.62  ? 56  ARG B CG  1 
ATOM   8476  C  CG  B ARG F 2 75  ? 24.13   -35.211 38.718 0.5 46.82  ? 56  ARG B CG  1 
ATOM   8477  C  CD  A ARG F 2 75  ? 24.064  -36.418 39.711 0.5 46.47  ? 56  ARG B CD  1 
ATOM   8478  C  CD  B ARG F 2 75  ? 24.047  -35.567 40.19  0.5 46.61  ? 56  ARG B CD  1 
ATOM   8479  N  NE  A ARG F 2 75  ? 23.585  -35.942 41.002 0.5 46.42  ? 56  ARG B NE  1 
ATOM   8480  N  NE  B ARG F 2 75  ? 25.363  -35.485 40.806 0.5 46.51  ? 56  ARG B NE  1 
ATOM   8481  C  CZ  A ARG F 2 75  ? 22.397  -36.234 41.518 0.5 47.05  ? 56  ARG B CZ  1 
ATOM   8482  C  CZ  B ARG F 2 75  ? 25.727  -34.573 41.696 0.5 45.44  ? 56  ARG B CZ  1 
ATOM   8483  N  NH1 A ARG F 2 75  ? 21.552  -37.001 40.85  0.5 46.58  ? 56  ARG B NH1 1 
ATOM   8484  N  NH1 B ARG F 2 75  ? 24.86   -33.662 42.103 0.5 46.52  ? 56  ARG B NH1 1 
ATOM   8485  N  NH2 A ARG F 2 75  ? 22.06   -35.761 42.704 0.5 47.31  ? 56  ARG B NH2 1 
ATOM   8486  N  NH2 B ARG F 2 75  ? 26.955  -34.585 42.181 0.5 44.32  ? 56  ARG B NH2 1 
ATOM   8487  N  N   . ALA F 2 76  ? 21.237  -34.834 35.141 1   49.85  ? 57  ALA B N   1 
ATOM   8488  C  CA  . ALA F 2 76  ? 19.941  -35.219 34.536 1   50.63  ? 57  ALA B CA  1 
ATOM   8489  C  C   . ALA F 2 76  ? 19.277  -36.226 35.48  1   51.37  ? 57  ALA B C   1 
ATOM   8490  O  O   . ALA F 2 76  ? 20.005  -36.829 36.292 1   50.55  ? 57  ALA B O   1 
ATOM   8491  C  CB  . ALA F 2 76  ? 20.156  -35.796 33.16  1   52.36  ? 57  ALA B CB  1 
ATOM   8492  N  N   . SER F 2 77  ? 17.954  -36.396 35.403 1   54.95  ? 58  SER B N   1 
ATOM   8493  C  CA  . SER F 2 77  ? 17.194  -37.311 36.298 1   55.59  ? 58  SER B CA  1 
ATOM   8494  C  C   . SER F 2 77  ? 17.617  -38.752 35.993 1   54.58  ? 58  SER B C   1 
ATOM   8495  O  O   . SER F 2 77  ? 17.834  -39.058 34.801 1   51.46  ? 58  SER B O   1 
ATOM   8496  C  CB  . SER F 2 77  ? 15.698  -37.124 36.182 1   58.02  ? 58  SER B CB  1 
ATOM   8497  O  OG  . SER F 2 77  ? 15.142  -37.988 35.198 1   61.62  ? 58  SER B OG  1 
ATOM   8498  N  N   . GLY F 2 78  ? 17.769  -39.577 37.035 1   56.24  ? 59  GLY B N   1 
ATOM   8499  C  CA  . GLY F 2 78  ? 18.241  -40.974 36.941 1   59.2   ? 59  GLY B CA  1 
ATOM   8500  C  C   . GLY F 2 78  ? 19.744  -41.096 37.159 1   61.06  ? 59  GLY B C   1 
ATOM   8501  O  O   . GLY F 2 78  ? 20.172  -42.149 37.678 1   66.68  ? 59  GLY B O   1 
ATOM   8502  N  N   . VAL F 2 79  ? 20.518  -40.066 36.794 1   56.42  ? 60  VAL B N   1 
ATOM   8503  C  CA  . VAL F 2 79  ? 22.008  -40.051 36.875 1   56.57  ? 60  VAL B CA  1 
ATOM   8504  C  C   . VAL F 2 79  ? 22.39   -40.084 38.355 1   57.84  ? 60  VAL B C   1 
ATOM   8505  O  O   . VAL F 2 79  ? 21.964  -39.215 39.11  1   58.46  ? 60  VAL B O   1 
ATOM   8506  C  CB  . VAL F 2 79  ? 22.605  -38.823 36.152 1   55.15  ? 60  VAL B CB  1 
ATOM   8507  C  CG1 . VAL F 2 79  ? 24.125  -38.783 36.22  1   53.47  ? 60  VAL B CG1 1 
ATOM   8508  C  CG2 . VAL F 2 79  ? 22.158  -38.741 34.7   1   55.5   ? 60  VAL B CG2 1 
ATOM   8509  N  N   . PRO F 2 80  ? 23.181  -41.079 38.828 1   60.25  ? 61  PRO B N   1 
ATOM   8510  C  CA  . PRO F 2 80  ? 23.59   -41.127 40.234 1   61.57  ? 61  PRO B CA  1 
ATOM   8511  C  C   . PRO F 2 80  ? 24.582  -40.011 40.608 1   61.69  ? 61  PRO B C   1 
ATOM   8512  O  O   . PRO F 2 80  ? 25.217  -39.461 39.717 1   57.99  ? 61  PRO B O   1 
ATOM   8513  C  CB  . PRO F 2 80  ? 24.224  -42.52  40.404 1   60.83  ? 61  PRO B CB  1 
ATOM   8514  C  CG  . PRO F 2 80  ? 24.627  -42.949 39.005 1   59.85  ? 61  PRO B CG  1 
ATOM   8515  C  CD  . PRO F 2 80  ? 23.71   -42.213 38.049 1   59.55  ? 61  PRO B CD  1 
ATOM   8516  N  N   . ASP F 2 81  ? 24.695  -39.721 41.911 1   62.39  ? 62  ASP B N   1 
ATOM   8517  C  CA  . ASP F 2 81  ? 25.528  -38.613 42.465 1   63.36  ? 62  ASP B CA  1 
ATOM   8518  C  C   . ASP F 2 81  ? 27.024  -38.934 42.318 1   59.34  ? 62  ASP B C   1 
ATOM   8519  O  O   . ASP F 2 81  ? 27.835  -37.994 42.456 1   60.89  ? 62  ASP B O   1 
ATOM   8520  C  CB  . ASP F 2 81  ? 25.144  -38.256 43.908 1   66.76  ? 62  ASP B CB  1 
ATOM   8521  C  CG  . ASP F 2 81  ? 25.199  -39.398 44.909 1   70.65  ? 62  ASP B CG  1 
ATOM   8522  O  OD1 . ASP F 2 81  ? 25.288  -40.568 44.474 1   75.52  ? 62  ASP B OD1 1 
ATOM   8523  O  OD2 . ASP F 2 81  ? 25.135  -39.107 46.121 1   69.93  ? 62  ASP B OD2 1 
ATOM   8524  N  N   . ARG F 2 82  ? 27.376  -40.195 42.037 1   55.82  ? 63  ARG B N   1 
ATOM   8525  C  CA  . ARG F 2 82  ? 28.736  -40.637 41.609 1   51.14  ? 63  ARG B CA  1 
ATOM   8526  C  C   . ARG F 2 82  ? 29.272  -39.72  40.5   1   48.61  ? 63  ARG B C   1 
ATOM   8527  O  O   . ARG F 2 82  ? 30.478  -39.412 40.533 1   50.34  ? 63  ARG B O   1 
ATOM   8528  C  CB  . ARG F 2 82  ? 28.711  -42.081 41.101 1   51.29  ? 63  ARG B CB  1 
ATOM   8529  C  CG  . ARG F 2 82  ? 28.206  -43.093 42.12  1   52.72  ? 63  ARG B CG  1 
ATOM   8530  C  CD  . ARG F 2 82  ? 28.678  -44.514 41.873 1   52.69  ? 63  ARG B CD  1 
ATOM   8531  N  NE  . ARG F 2 82  ? 28.067  -45.126 40.697 1   51.46  ? 63  ARG B NE  1 
ATOM   8532  C  CZ  . ARG F 2 82  ? 28.594  -45.182 39.47  1   49.55  ? 63  ARG B CZ  1 
ATOM   8533  N  NH1 . ARG F 2 82  ? 29.772  -44.64  39.198 1   50.37  ? 63  ARG B NH1 1 
ATOM   8534  N  NH2 . ARG F 2 82  ? 27.921  -45.785 38.505 1   48.63  ? 63  ARG B NH2 1 
ATOM   8535  N  N   . PHE F 2 83  ? 28.409  -39.311 39.562 1   45.75  ? 64  PHE B N   1 
ATOM   8536  C  CA  . PHE F 2 83  ? 28.718  -38.377 38.446 1   45.18  ? 64  PHE B CA  1 
ATOM   8537  C  C   . PHE F 2 83  ? 28.588  -36.939 38.956 1   46.03  ? 64  PHE B C   1 
ATOM   8538  O  O   . PHE F 2 83  ? 27.586  -36.636 39.629 1   49.16  ? 64  PHE B O   1 
ATOM   8539  C  CB  . PHE F 2 83  ? 27.803  -38.642 37.247 1   44.88  ? 64  PHE B CB  1 
ATOM   8540  C  CG  . PHE F 2 83  ? 27.99   -40.008 36.638 1   46.11  ? 64  PHE B CG  1 
ATOM   8541  C  CD1 . PHE F 2 83  ? 27.288  -41.103 37.125 1   47.23  ? 64  PHE B CD1 1 
ATOM   8542  C  CD2 . PHE F 2 83  ? 28.9    -40.21  35.609 1   46.33  ? 64  PHE B CD2 1 
ATOM   8543  C  CE1 . PHE F 2 83  ? 27.481  -42.367 36.584 1   49.23  ? 64  PHE B CE1 1 
ATOM   8544  C  CE2 . PHE F 2 83  ? 29.094  -41.473 35.069 1   46.85  ? 64  PHE B CE2 1 
ATOM   8545  C  CZ  . PHE F 2 83  ? 28.386  -42.549 35.558 1   49.06  ? 64  PHE B CZ  1 
ATOM   8546  N  N   . SER F 2 84  ? 29.584  -36.095 38.675 1   43.72  ? 65  SER B N   1 
ATOM   8547  C  CA  . SER F 2 84  ? 29.587  -34.651 39.024 1   43.27  ? 65  SER B CA  1 
ATOM   8548  C  C   . SER F 2 84  ? 30.428  -33.871 38.011 1   42.06  ? 65  SER B C   1 
ATOM   8549  O  O   . SER F 2 84  ? 31.422  -34.42  37.485 1   41.61  ? 65  SER B O   1 
ATOM   8550  C  CB  . SER F 2 84  ? 30.064  -34.416 40.444 1   45.02  ? 65  SER B CB  1 
ATOM   8551  O  OG  . SER F 2 84  ? 31.475  -34.259 40.513 1   44.75  ? 65  SER B OG  1 
ATOM   8552  N  N   . GLY F 2 85  ? 30.035  -32.625 37.768 1   41.09  ? 66  GLY B N   1 
ATOM   8553  C  CA  . GLY F 2 85  ? 30.702  -31.714 36.826 1   41.36  ? 66  GLY B CA  1 
ATOM   8554  C  C   . GLY F 2 85  ? 31.193  -30.469 37.53  1   40.66  ? 66  GLY B C   1 
ATOM   8555  O  O   . GLY F 2 85  ? 30.638  -30.116 38.58  1   38.09  ? 66  GLY B O   1 
ATOM   8556  N  N   . SER F 2 86  ? 32.223  -29.848 36.967 1   44.13  ? 67  SER B N   1 
ATOM   8557  C  CA  . SER F 2 86  ? 32.808  -28.573 37.441 1   47.92  ? 67  SER B CA  1 
ATOM   8558  C  C   . SER F 2 86  ? 33.432  -27.836 36.257 1   50.36  ? 67  SER B C   1 
ATOM   8559  O  O   . SER F 2 86  ? 33.658  -28.467 35.205 1   51.5   ? 67  SER B O   1 
ATOM   8560  C  CB  . SER F 2 86  ? 33.816  -28.807 38.541 1   50.45  ? 67  SER B CB  1 
ATOM   8561  O  OG  . SER F 2 86  ? 34.856  -29.676 38.109 1   52.77  ? 67  SER B OG  1 
ATOM   8562  N  N   . LYS F 2 87  ? 33.697  -26.547 36.457 1   54.92  ? 68  LYS B N   1 
ATOM   8563  C  CA  . LYS F 2 87  ? 34.306  -25.62  35.47  1   54.7   ? 68  LYS B CA  1 
ATOM   8564  C  C   . LYS F 2 87  ? 35.427  -24.86  36.185 1   52.84  ? 68  LYS B C   1 
ATOM   8565  O  O   . LYS F 2 87  ? 35.304  -24.625 37.403 1   51.33  ? 68  LYS B O   1 
ATOM   8566  C  CB  . LYS F 2 87  ? 33.213  -24.702 34.91  1   57     ? 68  LYS B CB  1 
ATOM   8567  C  CG  . LYS F 2 87  ? 33.68   -23.455 34.173 1   58.95  ? 68  LYS B CG  1 
ATOM   8568  C  CD  . LYS F 2 87  ? 32.54   -22.573 33.701 1   61.06  ? 68  LYS B CD  1 
ATOM   8569  C  CE  . LYS F 2 87  ? 32.82   -21.092 33.856 1   63.6   ? 68  LYS B CE  1 
ATOM   8570  N  NZ  . LYS F 2 87  ? 34.015  -20.664 33.09  1   65.95  ? 68  LYS B NZ  1 
ATOM   8571  N  N   . SER F 2 88  ? 36.481  -24.516 35.449 1   51.93  ? 69  SER B N   1 
ATOM   8572  C  CA  . SER F 2 88  ? 37.554  -23.59  35.885 1   52.25  ? 69  SER B CA  1 
ATOM   8573  C  C   . SER F 2 88  ? 38.114  -22.884 34.65  1   52.27  ? 69  SER B C   1 
ATOM   8574  O  O   . SER F 2 88  ? 38.826  -23.549 33.871 1   50.71  ? 69  SER B O   1 
ATOM   8575  C  CB  . SER F 2 88  ? 38.625  -24.315 36.651 1   53.29  ? 69  SER B CB  1 
ATOM   8576  O  OG  . SER F 2 88  ? 39.641  -23.414 37.065 1   53.22  ? 69  SER B OG  1 
ATOM   8577  N  N   . GLY F 2 89  ? 37.764  -21.605 34.472 1   52.01  ? 70  GLY B N   1 
ATOM   8578  C  CA  . GLY F 2 89  ? 38.177  -20.778 33.324 1   51.68  ? 70  GLY B CA  1 
ATOM   8579  C  C   . GLY F 2 89  ? 37.67   -21.36  32.016 1   51.94  ? 70  GLY B C   1 
ATOM   8580  O  O   . GLY F 2 89  ? 36.439  -21.425 31.841 1   52.74  ? 70  GLY B O   1 
ATOM   8581  N  N   . THR F 2 90  ? 38.583  -21.811 31.151 1   49.76  ? 71  THR B N   1 
ATOM   8582  C  CA  . THR F 2 90  ? 38.301  -22.208 29.746 1   50     ? 71  THR B CA  1 
ATOM   8583  C  C   . THR F 2 90  ? 38.185  -23.733 29.62  1   52.1   ? 71  THR B C   1 
ATOM   8584  O  O   . THR F 2 90  ? 38.016  -24.203 28.479 1   55.97  ? 71  THR B O   1 
ATOM   8585  C  CB  . THR F 2 90  ? 39.375  -21.653 28.805 1   49.36  ? 71  THR B CB  1 
ATOM   8586  O  OG1 . THR F 2 90  ? 40.589  -22.359 29.061 1   49.42  ? 71  THR B OG1 1 
ATOM   8587  C  CG2 . THR F 2 90  ? 39.597  -20.165 28.97  1   50.62  ? 71  THR B CG2 1 
ATOM   8588  N  N   . SER F 2 91  ? 38.273  -24.482 30.725 1   51.28  ? 72  SER B N   1 
ATOM   8589  C  CA  . SER F 2 91  ? 38.134  -25.96  30.732 1   53.71  ? 72  SER B CA  1 
ATOM   8590  C  C   . SER F 2 91  ? 37.146  -26.402 31.82  1   54.08  ? 72  SER B C   1 
ATOM   8591  O  O   . SER F 2 91  ? 37.09   -25.761 32.89  1   54.6   ? 72  SER B O   1 
ATOM   8592  C  CB  . SER F 2 91  ? 39.47   -26.642 30.883 1   55.57  ? 72  SER B CB  1 
ATOM   8593  O  OG  . SER F 2 91  ? 39.971  -26.495 32.204 1   58.29  ? 72  SER B OG  1 
ATOM   8594  N  N   . ALA F 2 92  ? 36.383  -27.454 31.52  1   52.7   ? 73  ALA B N   1 
ATOM   8595  C  CA  . ALA F 2 92  ? 35.489  -28.176 32.451 1   51.68  ? 73  ALA B CA  1 
ATOM   8596  C  C   . ALA F 2 92  ? 35.973  -29.623 32.564 1   51.11  ? 73  ALA B C   1 
ATOM   8597  O  O   . ALA F 2 92  ? 36.733  -30.078 31.673 1   50.21  ? 73  ALA B O   1 
ATOM   8598  C  CB  . ALA F 2 92  ? 34.067  -28.106 31.954 1   51.79  ? 73  ALA B CB  1 
ATOM   8599  N  N   . SER F 2 93  ? 35.559  -30.317 33.621 1   48.06  ? 74  SER B N   1 
ATOM   8600  C  CA  . SER F 2 93  ? 35.871  -31.752 33.819 1   48.28  ? 74  SER B CA  1 
ATOM   8601  C  C   . SER F 2 93  ? 34.676  -32.467 34.445 1   45.95  ? 74  SER B C   1 
ATOM   8602  O  O   . SER F 2 93  ? 34.07   -31.917 35.39  1   45.92  ? 74  SER B O   1 
ATOM   8603  C  CB  . SER F 2 93  ? 37.138  -31.945 34.62  1   50.15  ? 74  SER B CB  1 
ATOM   8604  O  OG  . SER F 2 93  ? 37.027  -31.38  35.914 1   51.33  ? 74  SER B OG  1 
ATOM   8605  N  N   . LEU F 2 94  ? 34.339  -33.63  33.885 1   45.93  ? 75  LEU B N   1 
ATOM   8606  C  CA  . LEU F 2 94  ? 33.428  -34.633 34.493 1   44.81  ? 75  LEU B CA  1 
ATOM   8607  C  C   . LEU F 2 94  ? 34.244  -35.376 35.551 1   44.58  ? 75  LEU B C   1 
ATOM   8608  O  O   . LEU F 2 94  ? 35.454  -35.556 35.327 1   49.74  ? 75  LEU B O   1 
ATOM   8609  C  CB  . LEU F 2 94  ? 32.907  -35.578 33.401 1   43.86  ? 75  LEU B CB  1 
ATOM   8610  C  CG  . LEU F 2 94  ? 31.974  -36.703 33.853 1   43.26  ? 75  LEU B CG  1 
ATOM   8611  C  CD1 . LEU F 2 94  ? 30.658  -36.151 34.38  1   43.48  ? 75  LEU B CD1 1 
ATOM   8612  C  CD2 . LEU F 2 94  ? 31.721  -37.679 32.719 1   42.52  ? 75  LEU B CD2 1 
ATOM   8613  N  N   . ALA F 2 95  ? 33.615  -35.758 36.658 1   43.19  ? 76  ALA B N   1 
ATOM   8614  C  CA  . ALA F 2 95  ? 34.228  -36.556 37.742 1   43.09  ? 76  ALA B CA  1 
ATOM   8615  C  C   . ALA F 2 95  ? 33.302  -37.727 38.08  1   42.52  ? 76  ALA B C   1 
ATOM   8616  O  O   . ALA F 2 95  ? 32.104  -37.484 38.31  1   43.09  ? 76  ALA B O   1 
ATOM   8617  C  CB  . ALA F 2 95  ? 34.481  -35.684 38.945 1   43.52  ? 76  ALA B CB  1 
ATOM   8618  N  N   . ILE F 2 96  ? 33.848  -38.945 38.093 1   42.1   ? 77  ILE B N   1 
ATOM   8619  C  CA  . ILE F 2 96  ? 33.132  -40.196 38.471 1   44.35  ? 77  ILE B CA  1 
ATOM   8620  C  C   . ILE F 2 96  ? 33.821  -40.758 39.721 1   46.62  ? 77  ILE B C   1 
ATOM   8621  O  O   . ILE F 2 96  ? 35.042  -40.973 39.649 1   45.48  ? 77  ILE B O   1 
ATOM   8622  C  CB  . ILE F 2 96  ? 33.124  -41.199 37.298 1   43.46  ? 77  ILE B CB  1 
ATOM   8623  C  CG1 . ILE F 2 96  ? 32.579  -40.568 36.012 1   41.63  ? 77  ILE B CG1 1 
ATOM   8624  C  CG2 . ILE F 2 96  ? 32.356  -42.466 37.667 1   44.41  ? 77  ILE B CG2 1 
ATOM   8625  C  CD1 . ILE F 2 96  ? 33.036  -41.248 34.751 1   42.09  ? 77  ILE B CD1 1 
ATOM   8626  N  N   . THR F 2 97  ? 33.074  -40.936 40.821 1   47.39  ? 78  THR B N   1 
ATOM   8627  C  CA  . THR F 2 97  ? 33.506  -41.662 42.048 1   46.96  ? 78  THR B CA  1 
ATOM   8628  C  C   . THR F 2 97  ? 32.889  -43.059 42.028 1   48.37  ? 78  THR B C   1 
ATOM   8629  O  O   . THR F 2 97  ? 32.013  -43.306 41.173 1   51.26  ? 78  THR B O   1 
ATOM   8630  C  CB  . THR F 2 97  ? 33.112  -40.946 43.347 1   47.56  ? 78  THR B CB  1 
ATOM   8631  O  OG1 . THR F 2 97  ? 31.706  -41.099 43.563 1   47.77  ? 78  THR B OG1 1 
ATOM   8632  C  CG2 . THR F 2 97  ? 33.496  -39.483 43.351 1   47.88  ? 78  THR B CG2 1 
ATOM   8633  N  N   . GLY F 2 98  ? 33.327  -43.924 42.947 1   49.16  ? 79  GLY B N   1 
ATOM   8634  C  CA  . GLY F 2 98  ? 32.877  -45.324 43.058 1   48.2   ? 79  GLY B CA  1 
ATOM   8635  C  C   . GLY F 2 98  ? 32.791  -45.998 41.701 1   45.85  ? 79  GLY B C   1 
ATOM   8636  O  O   . GLY F 2 98  ? 31.777  -46.667 41.454 1   49.32  ? 79  GLY B O   1 
ATOM   8637  N  N   . LEU F 2 99  ? 33.817  -45.819 40.861 1   43.6   ? 80  LEU B N   1 
ATOM   8638  C  CA  . LEU F 2 99  ? 33.854  -46.259 39.438 1   43.09  ? 80  LEU B CA  1 
ATOM   8639  C  C   . LEU F 2 99  ? 33.481  -47.742 39.357 1   43.65  ? 80  LEU B C   1 
ATOM   8640  O  O   . LEU F 2 99  ? 34.057  -48.53  40.121 1   44.88  ? 80  LEU B O   1 
ATOM   8641  C  CB  . LEU F 2 99  ? 35.26   -46.001 38.882 1   42.63  ? 80  LEU B CB  1 
ATOM   8642  C  CG  . LEU F 2 99  ? 35.511  -46.401 37.431 1   42.27  ? 80  LEU B CG  1 
ATOM   8643  C  CD1 . LEU F 2 99  ? 34.658  -45.579 36.48  1   42.82  ? 80  LEU B CD1 1 
ATOM   8644  C  CD2 . LEU F 2 99  ? 36.98   -46.236 37.086 1   43.03  ? 80  LEU B CD2 1 
ATOM   8645  N  N   . GLN F 2 100 ? 32.524  -48.083 38.493 1   47.02  ? 81  GLN B N   1 
ATOM   8646  C  CA  . GLN F 2 100 ? 32.004  -49.46  38.268 1   49.98  ? 81  GLN B CA  1 
ATOM   8647  C  C   . GLN F 2 100 ? 32.204  -49.828 36.799 1   48.49  ? 81  GLN B C   1 
ATOM   8648  O  O   . GLN F 2 100 ? 32.192  -48.905 35.962 1   50.34  ? 81  GLN B O   1 
ATOM   8649  C  CB  . GLN F 2 100 ? 30.506  -49.547 38.564 1   56.51  ? 81  GLN B CB  1 
ATOM   8650  C  CG  . GLN F 2 100 ? 30.136  -49.326 40.023 1   60.99  ? 81  GLN B CG  1 
ATOM   8651  C  CD  . GLN F 2 100 ? 28.651  -49.103 40.188 1   65.28  ? 81  GLN B CD  1 
ATOM   8652  O  OE1 . GLN F 2 100 ? 27.835  -49.722 39.503 1   65.3   ? 81  GLN B OE1 1 
ATOM   8653  N  NE2 . GLN F 2 100 ? 28.285  -48.212 41.099 1   66.88  ? 81  GLN B NE2 1 
ATOM   8654  N  N   . ALA F 2 101 ? 32.309  -51.126 36.501 1   47.04  ? 82  ALA B N   1 
ATOM   8655  C  CA  . ALA F 2 101 ? 32.421  -51.688 35.133 1   46.82  ? 82  ALA B CA  1 
ATOM   8656  C  C   . ALA F 2 101 ? 31.248  -51.207 34.262 1   45.2   ? 82  ALA B C   1 
ATOM   8657  O  O   . ALA F 2 101 ? 31.445  -51.045 33.051 1   44.38  ? 82  ALA B O   1 
ATOM   8658  C  CB  . ALA F 2 101 ? 32.482  -53.196 35.206 1   48.08  ? 82  ALA B CB  1 
ATOM   8659  N  N   . GLU F 2 102 ? 30.084  -50.969 34.874 1   47.17  ? 83  GLU B N   1 
ATOM   8660  C  CA  . GLU F 2 102 ? 28.874  -50.352 34.256 1   49.72  ? 83  GLU B CA  1 
ATOM   8661  C  C   . GLU F 2 102 ? 29.205  -49.002 33.593 1   47.86  ? 83  GLU B C   1 
ATOM   8662  O  O   . GLU F 2 102 ? 28.499  -48.647 32.627 1   48.83  ? 83  GLU B O   1 
ATOM   8663  C  CB  . GLU F 2 102 ? 27.777  -50.147 35.308 1   54.08  ? 83  GLU B CB  1 
ATOM   8664  C  CG  . GLU F 2 102 ? 26.936  -51.388 35.577 1   58.56  ? 83  GLU B CG  1 
ATOM   8665  C  CD  . GLU F 2 102 ? 27.646  -52.567 36.228 1   61.71  ? 83  GLU B CD  1 
ATOM   8666  O  OE1 . GLU F 2 102 ? 28.536  -52.332 37.082 1   63.36  ? 83  GLU B OE1 1 
ATOM   8667  O  OE2 . GLU F 2 102 ? 27.308  -53.722 35.879 1   61.68  ? 83  GLU B OE2 1 
ATOM   8668  N  N   . ASP F 2 103 ? 30.213  -48.273 34.091 1   43.58  ? 84  ASP B N   1 
ATOM   8669  C  CA  . ASP F 2 103 ? 30.565  -46.902 33.635 1   43.06  ? 84  ASP B CA  1 
ATOM   8670  C  C   . ASP F 2 103 ? 31.394  -46.929 32.345 1   41.53  ? 84  ASP B C   1 
ATOM   8671  O  O   . ASP F 2 103 ? 31.607  -45.845 31.785 1   41.07  ? 84  ASP B O   1 
ATOM   8672  C  CB  . ASP F 2 103 ? 31.308  -46.124 34.724 1   43.14  ? 84  ASP B CB  1 
ATOM   8673  C  CG  . ASP F 2 103 ? 30.531  -45.986 36.023 1   43.11  ? 84  ASP B CG  1 
ATOM   8674  O  OD1 . ASP F 2 103 ? 29.286  -45.882 35.971 1   42.93  ? 84  ASP B OD1 1 
ATOM   8675  O  OD2 . ASP F 2 103 ? 31.178  -45.964 37.081 1   45.17  ? 84  ASP B OD2 1 
ATOM   8676  N  N   . GLU F 2 104 ? 31.842  -48.097 31.881 1   42.22  ? 85  GLU B N   1 
ATOM   8677  C  CA  . GLU F 2 104 ? 32.621  -48.225 30.618 1   42.63  ? 85  GLU B CA  1 
ATOM   8678  C  C   . GLU F 2 104 ? 31.773  -47.739 29.438 1   40.81  ? 85  GLU B C   1 
ATOM   8679  O  O   . GLU F 2 104 ? 30.751  -48.381 29.142 1   43.29  ? 85  GLU B O   1 
ATOM   8680  C  CB  . GLU F 2 104 ? 33.082  -49.662 30.389 1   43.06  ? 85  GLU B CB  1 
ATOM   8681  C  CG  . GLU F 2 104 ? 34.349  -50.007 31.14  1   44.98  ? 85  GLU B CG  1 
ATOM   8682  C  CD  . GLU F 2 104 ? 34.965  -51.313 30.685 1   46.56  ? 85  GLU B CD  1 
ATOM   8683  O  OE1 . GLU F 2 104 ? 34.191  -52.264 30.421 1   48.8   ? 85  GLU B OE1 1 
ATOM   8684  O  OE2 . GLU F 2 104 ? 36.209  -51.382 30.593 1   45.22  ? 85  GLU B OE2 1 
ATOM   8685  N  N   . ALA F 2 105 ? 32.202  -46.65  28.799 1   39.2   ? 86  ALA B N   1 
ATOM   8686  C  CA  . ALA F 2 105 ? 31.474  -45.947 27.718 1   38.98  ? 86  ALA B CA  1 
ATOM   8687  C  C   . ALA F 2 105 ? 32.364  -44.856 27.124 1   38.9   ? 86  ALA B C   1 
ATOM   8688  O  O   . ALA F 2 105 ? 33.405  -44.558 27.727 1   41.25  ? 86  ALA B O   1 
ATOM   8689  C  CB  . ALA F 2 105 ? 30.209  -45.341 28.272 1   39.75  ? 86  ALA B CB  1 
ATOM   8690  N  N   . ASP F 2 106 ? 31.953  -44.28  25.996 1   38.23  ? 87  ASP B N   1 
ATOM   8691  C  CA  . ASP F 2 106 ? 32.498  -42.996 25.486 1   39.53  ? 87  ASP B CA  1 
ATOM   8692  C  C   . ASP F 2 106 ? 31.772  -41.852 26.201 1   37.35  ? 87  ASP B C   1 
ATOM   8693  O  O   . ASP F 2 106 ? 30.539  -41.936 26.331 1   37.01  ? 87  ASP B O   1 
ATOM   8694  C  CB  . ASP F 2 106 ? 32.355  -42.887 23.967 1   42.91  ? 87  ASP B CB  1 
ATOM   8695  C  CG  . ASP F 2 106 ? 33.11   -43.956 23.193 1   43.98  ? 87  ASP B CG  1 
ATOM   8696  O  OD1 . ASP F 2 106 ? 34.11   -44.47  23.725 1   42.68  ? 87  ASP B OD1 1 
ATOM   8697  O  OD2 . ASP F 2 106 ? 32.691  -44.258 22.055 1   46.8   ? 87  ASP B OD2 1 
ATOM   8698  N  N   . TYR F 2 107 ? 32.514  -40.829 26.635 1   36.11  ? 88  TYR B N   1 
ATOM   8699  C  CA  . TYR F 2 107 ? 31.992  -39.611 27.307 1   34.47  ? 88  TYR B CA  1 
ATOM   8700  C  C   . TYR F 2 107 ? 32.35   -38.384 26.469 1   35.06  ? 88  TYR B C   1 
ATOM   8701  O  O   . TYR F 2 107 ? 33.545  -38.163 26.222 1   35.17  ? 88  TYR B O   1 
ATOM   8702  C  CB  . TYR F 2 107 ? 32.543  -39.512 28.729 1   33.3   ? 88  TYR B CB  1 
ATOM   8703  C  CG  . TYR F 2 107 ? 32.006  -40.583 29.638 1   32.44  ? 88  TYR B CG  1 
ATOM   8704  C  CD1 . TYR F 2 107 ? 32.516  -41.87  29.603 1   33.35  ? 88  TYR B CD1 1 
ATOM   8705  C  CD2 . TYR F 2 107 ? 30.95   -40.327 30.494 1   33.04  ? 88  TYR B CD2 1 
ATOM   8706  C  CE1 . TYR F 2 107 ? 32.006  -42.871 30.416 1   33.69  ? 88  TYR B CE1 1 
ATOM   8707  C  CE2 . TYR F 2 107 ? 30.429  -41.315 31.313 1   33.06  ? 88  TYR B CE2 1 
ATOM   8708  C  CZ  . TYR F 2 107 ? 30.956  -42.591 31.274 1   32.95  ? 88  TYR B CZ  1 
ATOM   8709  O  OH  . TYR F 2 107 ? 30.434  -43.549 32.091 1   34.06  ? 88  TYR B OH  1 
ATOM   8710  N  N   . TYR F 2 108 ? 31.337  -37.627 26.041 1   36.54  ? 89  TYR B N   1 
ATOM   8711  C  CA  . TYR F 2 108 ? 31.485  -36.358 25.285 1   37.95  ? 89  TYR B CA  1 
ATOM   8712  C  C   . TYR F 2 108 ? 30.991  -35.192 26.141 1   39.16  ? 89  TYR B C   1 
ATOM   8713  O  O   . TYR F 2 108 ? 29.869  -35.254 26.663 1   39.08  ? 89  TYR B O   1 
ATOM   8714  C  CB  . TYR F 2 108 ? 30.702  -36.395 23.973 1   38.24  ? 89  TYR B CB  1 
ATOM   8715  C  CG  . TYR F 2 108 ? 31.072  -37.525 23.05  1   38.73  ? 89  TYR B CG  1 
ATOM   8716  C  CD1 . TYR F 2 108 ? 30.442  -38.756 23.151 1   38.28  ? 89  TYR B CD1 1 
ATOM   8717  C  CD2 . TYR F 2 108 ? 32.042  -37.366 22.072 1   38.55  ? 89  TYR B CD2 1 
ATOM   8718  C  CE1 . TYR F 2 108 ? 30.77   -39.803 22.306 1   39.9   ? 89  TYR B CE1 1 
ATOM   8719  C  CE2 . TYR F 2 108 ? 32.386  -38.408 21.223 1   38.83  ? 89  TYR B CE2 1 
ATOM   8720  C  CZ  . TYR F 2 108 ? 31.747  -39.629 21.341 1   39.39  ? 89  TYR B CZ  1 
ATOM   8721  O  OH  . TYR F 2 108 ? 32.067  -40.662 20.514 1   43.13  ? 89  TYR B OH  1 
ATOM   8722  N  N   . CYS F 2 109 ? 31.827  -34.166 26.288 1   41.66  ? 90  CYS B N   1 
ATOM   8723  C  CA  . CYS F 2 109 ? 31.406  -32.808 26.706 1   43.98  ? 90  CYS B CA  1 
ATOM   8724  C  C   . CYS F 2 109 ? 30.899  -32.079 25.461 1   42.63  ? 90  CYS B C   1 
ATOM   8725  O  O   . CYS F 2 109 ? 31.356  -32.414 24.35  1   41.9   ? 90  CYS B O   1 
ATOM   8726  C  CB  . CYS F 2 109 ? 32.535  -32.019 27.362 1   46.88  ? 90  CYS B CB  1 
ATOM   8727  S  SG  . CYS F 2 109 ? 33.986  -31.768 26.301 1   51.09  ? 90  CYS B SG  1 
ATOM   8728  N  N   . ALA F 2 110 ? 29.975  -31.144 25.649 1   41.1   ? 91  ALA B N   1 
ATOM   8729  C  CA  . ALA F 2 110 ? 29.564  -30.153 24.632 1   42.52  ? 91  ALA B CA  1 
ATOM   8730  C  C   . ALA F 2 110 ? 29.457  -28.787 25.304 1   43.57  ? 91  ALA B C   1 
ATOM   8731  O  O   . ALA F 2 110 ? 29.39   -28.742 26.551 1   43.36  ? 91  ALA B O   1 
ATOM   8732  C  CB  . ALA F 2 110 ? 28.262  -30.551 23.989 1   42.69  ? 91  ALA B CB  1 
ATOM   8733  N  N   . SER F 2 111 ? 29.467  -27.723 24.503 1   44.67  ? 92  SER B N   1 
ATOM   8734  C  CA  . SER F 2 111 ? 29.3    -26.324 24.971 1   45.93  ? 92  SER B CA  1 
ATOM   8735  C  C   . SER F 2 111 ? 28.675  -25.468 23.869 1   46.02  ? 92  SER B C   1 
ATOM   8736  O  O   . SER F 2 111 ? 29.044  -25.651 22.686 1   45.21  ? 92  SER B O   1 
ATOM   8737  C  CB  . SER F 2 111 ? 30.609  -25.742 25.432 1   46.75  ? 92  SER B CB  1 
ATOM   8738  O  OG  . SER F 2 111 ? 30.42   -24.441 25.97  1   46.49  ? 92  SER B OG  1 
ATOM   8739  N  N   . HIS F 2 112 ? 27.768  -24.566 24.253 1   46.58  ? 93  HIS B N   1 
ATOM   8740  C  CA  . HIS F 2 112 ? 27.353  -23.414 23.413 1   49.77  ? 93  HIS B CA  1 
ATOM   8741  C  C   . HIS F 2 112 ? 28.604  -22.581 23.113 1   48.45  ? 93  HIS B C   1 
ATOM   8742  O  O   . HIS F 2 112 ? 29.45   -22.446 24.013 1   46.47  ? 93  HIS B O   1 
ATOM   8743  C  CB  . HIS F 2 112 ? 26.246  -22.589 24.089 1   51.66  ? 93  HIS B CB  1 
ATOM   8744  C  CG  . HIS F 2 112 ? 25.882  -21.359 23.324 1   54.77  ? 93  HIS B CG  1 
ATOM   8745  N  ND1 . HIS F 2 112 ? 26.312  -20.098 23.7   1   56.04  ? 93  HIS B ND1 1 
ATOM   8746  C  CD2 . HIS F 2 112 ? 25.168  -21.194 22.19  1   54.19  ? 93  HIS B CD2 1 
ATOM   8747  C  CE1 . HIS F 2 112 ? 25.865  -19.21  22.838 1   56     ? 93  HIS B CE1 1 
ATOM   8748  N  NE2 . HIS F 2 112 ? 25.164  -19.857 21.9   1   55.32  ? 93  HIS B NE2 1 
ATOM   8749  N  N   . ARG F 2 113 ? 28.729  -22.094 21.88  1   50.51  ? 94  ARG B N   1 
ATOM   8750  C  CA  . ARG F 2 113 ? 29.824  -21.195 21.432 1   54.86  ? 94  ARG B CA  1 
ATOM   8751  C  C   . ARG F 2 113 ? 29.182  -19.883 20.958 1   57.62  ? 94  ARG B C   1 
ATOM   8752  O  O   . ARG F 2 113 ? 27.975  -19.907 20.631 1   56.95  ? 94  ARG B O   1 
ATOM   8753  C  CB  . ARG F 2 113 ? 30.672  -21.91  20.372 1   54.37  ? 94  ARG B CB  1 
ATOM   8754  C  CG  . ARG F 2 113 ? 31.883  -21.119 19.9   1   56     ? 94  ARG B CG  1 
ATOM   8755  C  CD  . ARG F 2 113 ? 32.88   -21.958 19.124 1   55.7   ? 94  ARG B CD  1 
ATOM   8756  N  NE  . ARG F 2 113 ? 33.809  -22.671 19.991 1   57.82  ? 94  ARG B NE  1 
ATOM   8757  C  CZ  . ARG F 2 113 ? 34.752  -23.525 19.581 1   61.47  ? 94  ARG B CZ  1 
ATOM   8758  N  NH1 . ARG F 2 113 ? 34.908  -23.803 18.294 1   61.68  ? 94  ARG B NH1 1 
ATOM   8759  N  NH2 . ARG F 2 113 ? 35.533  -24.115 20.473 1   62.63  ? 94  ARG B NH2 1 
ATOM   8760  N  N   . SER F 2 114 ? 29.948  -18.784 20.95  1   62.13  ? 95  SER B N   1 
ATOM   8761  C  CA  . SER F 2 114 ? 29.486  -17.401 20.63  1   62.88  ? 95  SER B CA  1 
ATOM   8762  C  C   . SER F 2 114 ? 28.792  -17.351 19.26  1   63.95  ? 95  SER B C   1 
ATOM   8763  O  O   . SER F 2 114 ? 27.828  -16.572 19.124 1   61.5   ? 95  SER B O   1 
ATOM   8764  C  CB  . SER F 2 114 ? 30.626  -16.408 20.688 1   64.66  ? 95  SER B CB  1 
ATOM   8765  O  OG  . SER F 2 114 ? 31.201  -16.348 21.987 1   64.8   ? 95  SER B OG  1 
ATOM   8766  N  N   . ASN F 2 115 ? 29.235  -18.175 18.301 1   65.69  ? 96  ASN B N   1 
ATOM   8767  C  CA  . ASN F 2 115 ? 28.731  -18.198 16.898 1   68.41  ? 96  ASN B CA  1 
ATOM   8768  C  C   . ASN F 2 115 ? 27.411  -18.987 16.786 1   69.42  ? 96  ASN B C   1 
ATOM   8769  O  O   . ASN F 2 115 ? 27.066  -19.376 15.653 1   71.75  ? 96  ASN B O   1 
ATOM   8770  C  CB  . ASN F 2 115 ? 29.805  -18.724 15.935 1   69.93  ? 96  ASN B CB  1 
ATOM   8771  C  CG  . ASN F 2 115 ? 30.298  -20.123 16.251 1   72.83  ? 96  ASN B CG  1 
ATOM   8772  O  OD1 . ASN F 2 115 ? 29.84   -20.755 17.201 1   77.77  ? 96  ASN B OD1 1 
ATOM   8773  N  ND2 . ASN F 2 115 ? 31.251  -20.612 15.474 1   72.91  ? 96  ASN B ND2 1 
ATOM   8774  N  N   . ASN F 2 116 ? 26.695  -19.212 17.898 1   69.32  ? 97  ASN B N   1 
ATOM   8775  C  CA  . ASN F 2 116 ? 25.428  -19.992 17.984 1   69.02  ? 97  ASN B CA  1 
ATOM   8776  C  C   . ASN F 2 116 ? 25.627  -21.423 17.458 1   62.62  ? 97  ASN B C   1 
ATOM   8777  O  O   . ASN F 2 116 ? 24.636  -22.025 17.005 1   63.95  ? 97  ASN B O   1 
ATOM   8778  C  CB  . ASN F 2 116 ? 24.274  -19.267 17.282 1   74.84  ? 97  ASN B CB  1 
ATOM   8779  C  CG  . ASN F 2 116 ? 23.79   -18.054 18.046 1   80.43  ? 97  ASN B CG  1 
ATOM   8780  O  OD1 . ASN F 2 116 ? 23.844  -16.938 17.535 1   83.03  ? 97  ASN B OD1 1 
ATOM   8781  N  ND2 . ASN F 2 116 ? 23.312  -18.26  19.264 1   83.6   ? 97  ASN B ND2 1 
ATOM   8782  N  N   . ASN F 2 117 ? 26.847  -21.96  17.546 1   57.68  ? 98  ASN B N   1 
ATOM   8783  C  CA  . ASN F 2 117 ? 27.131  -23.408 17.387 1   55.82  ? 98  ASN B CA  1 
ATOM   8784  C  C   . ASN F 2 117 ? 26.963  -24.09  18.747 1   54.45  ? 98  ASN B C   1 
ATOM   8785  O  O   . ASN F 2 117 ? 26.959  -23.387 19.783 1   53.31  ? 98  ASN B O   1 
ATOM   8786  C  CB  . ASN F 2 117 ? 28.539  -23.675 16.852 1   55.91  ? 98  ASN B CB  1 
ATOM   8787  C  CG  . ASN F 2 117 ? 28.725  -23.232 15.417 1   56.99  ? 98  ASN B CG  1 
ATOM   8788  O  OD1 . ASN F 2 117 ? 28.031  -22.334 14.938 1   55.57  ? 98  ASN B OD1 1 
ATOM   8789  N  ND2 . ASN F 2 117 ? 29.654  -23.866 14.72  1   56.51  ? 98  ASN B ND2 1 
ATOM   8790  N  N   . ILE F 2 118 ? 26.803  -25.413 18.728 1   50.16  ? 99  ILE B N   1 
ATOM   8791  C  CA  . ILE F 2 118 ? 27.043  -26.308 19.895 1   48.64  ? 99  ILE B CA  1 
ATOM   8792  C  C   . ILE F 2 118 ? 28.273  -27.139 19.518 1   47.67  ? 99  ILE B C   1 
ATOM   8793  O  O   . ILE F 2 118 ? 28.19   -27.869 18.523 1   49.03  ? 99  ILE B O   1 
ATOM   8794  C  CB  . ILE F 2 118 ? 25.793  -27.155 20.227 1   48.27  ? 99  ILE B CB  1 
ATOM   8795  C  CG1 . ILE F 2 118 ? 24.608  -26.285 20.663 1   48.45  ? 99  ILE B CG1 1 
ATOM   8796  C  CG2 . ILE F 2 118 ? 26.101  -28.208 21.281 1   48.68  ? 99  ILE B CG2 1 
ATOM   8797  C  CD1 . ILE F 2 118 ? 23.258  -26.919 20.569 0   47.15  ? 99  ILE B CD1 1 
ATOM   8798  N  N   . VAL F 2 119 ? 29.384  -26.981 20.242 1   46.5   ? 100 VAL B N   1 
ATOM   8799  C  CA  . VAL F 2 119 ? 30.689  -27.637 19.927 1   46.38  ? 100 VAL B CA  1 
ATOM   8800  C  C   . VAL F 2 119 ? 30.86   -28.843 20.853 1   44.42  ? 100 VAL B C   1 
ATOM   8801  O  O   . VAL F 2 119 ? 30.752  -28.661 22.077 1   41.83  ? 100 VAL B O   1 
ATOM   8802  C  CB  . VAL F 2 119 ? 31.866  -26.65  20.051 1   48.59  ? 100 VAL B CB  1 
ATOM   8803  C  CG1 . VAL F 2 119 ? 33.186  -27.281 19.633 1   49.56  ? 100 VAL B CG1 1 
ATOM   8804  C  CG2 . VAL F 2 119 ? 31.618  -25.389 19.245 1   48.8   ? 100 VAL B CG2 1 
ATOM   8805  N  N   . PHE F 2 120 ? 31.113  -30.021 20.274 1   44.78  ? 101 PHE B N   1 
ATOM   8806  C  CA  . PHE F 2 120 ? 31.383  -31.288 21.004 1   44.19  ? 101 PHE B CA  1 
ATOM   8807  C  C   . PHE F 2 120 ? 32.892  -31.427 21.21  1   44.27  ? 101 PHE B C   1 
ATOM   8808  O  O   . PHE F 2 120 ? 33.668  -30.806 20.46  1   44.33  ? 101 PHE B O   1 
ATOM   8809  C  CB  . PHE F 2 120 ? 30.821  -32.504 20.257 1   42.08  ? 101 PHE B CB  1 
ATOM   8810  C  CG  . PHE F 2 120 ? 29.378  -32.813 20.565 1   41.69  ? 101 PHE B CG  1 
ATOM   8811  C  CD1 . PHE F 2 120 ? 29.036  -33.544 21.694 1   40.85  ? 101 PHE B CD1 1 
ATOM   8812  C  CD2 . PHE F 2 120 ? 28.361  -32.375 19.732 1   41.58  ? 101 PHE B CD2 1 
ATOM   8813  C  CE1 . PHE F 2 120 ? 27.71   -33.822 21.985 1   40.09  ? 101 PHE B CE1 1 
ATOM   8814  C  CE2 . PHE F 2 120 ? 27.035  -32.657 20.023 1   41.71  ? 101 PHE B CE2 1 
ATOM   8815  C  CZ  . PHE F 2 120 ? 26.711  -33.379 21.149 1   40.64  ? 101 PHE B CZ  1 
ATOM   8816  N  N   . GLY F 2 121 ? 33.283  -32.223 22.206 1   44.95  ? 102 GLY B N   1 
ATOM   8817  C  CA  . GLY F 2 121 ? 34.664  -32.708 22.372 1   45.2   ? 102 GLY B CA  1 
ATOM   8818  C  C   . GLY F 2 121 ? 34.939  -33.906 21.478 1   46.86  ? 102 GLY B C   1 
ATOM   8819  O  O   . GLY F 2 121 ? 33.974  -34.469 20.916 1   48.91  ? 102 GLY B O   1 
ATOM   8820  N  N   . GLY F 2 122 ? 36.215  -34.278 21.339 1   48.29  ? 103 GLY B N   1 
ATOM   8821  C  CA  . GLY F 2 122 ? 36.669  -35.462 20.582 1   48.45  ? 103 GLY B CA  1 
ATOM   8822  C  C   . GLY F 2 122 ? 36.1    -36.756 21.144 1   47.88  ? 103 GLY B C   1 
ATOM   8823  O  O   . GLY F 2 122 ? 35.961  -37.715 20.365 1   50.44  ? 103 GLY B O   1 
ATOM   8824  N  N   . GLY F 2 123 ? 35.784  -36.782 22.445 1   46.57  ? 104 GLY B N   1 
ATOM   8825  C  CA  . GLY F 2 123 ? 35.24   -37.95  23.162 1   45.46  ? 104 GLY B CA  1 
ATOM   8826  C  C   . GLY F 2 123 ? 36.339  -38.679 23.906 1   45.03  ? 104 GLY B C   1 
ATOM   8827  O  O   . GLY F 2 123 ? 37.498  -38.589 23.464 1   44.92  ? 104 GLY B O   1 
ATOM   8828  N  N   . THR F 2 124 ? 35.985  -39.374 24.99  1   44.51  ? 105 THR B N   1 
ATOM   8829  C  CA  . THR F 2 124 ? 36.918  -40.086 25.903 1   44.15  ? 105 THR B CA  1 
ATOM   8830  C  C   . THR F 2 124 ? 36.386  -41.5   26.153 1   44.58  ? 105 THR B C   1 
ATOM   8831  O  O   . THR F 2 124 ? 35.295  -41.604 26.736 1   44.68  ? 105 THR B O   1 
ATOM   8832  C  CB  . THR F 2 124 ? 37.077  -39.306 27.213 1   44.79  ? 105 THR B CB  1 
ATOM   8833  O  OG1 . THR F 2 124 ? 37.552  -37.999 26.898 1   44.59  ? 105 THR B OG1 1 
ATOM   8834  C  CG2 . THR F 2 124 ? 38.029  -39.95  28.195 1   45.4   ? 105 THR B CG2 1 
ATOM   8835  N  N   . LYS F 2 125 ? 37.126  -42.531 25.725 1   45.65  ? 106 LYS B N   1 
ATOM   8836  C  CA  . LYS F 2 125 ? 36.836  -43.96  26.026 1   46.42  ? 106 LYS B CA  1 
ATOM   8837  C  C   . LYS F 2 125 ? 37.26   -44.232 27.475 1   44.76  ? 106 LYS B C   1 
ATOM   8838  O  O   . LYS F 2 125 ? 38.462  -44.128 27.75  1   45.77  ? 106 LYS B O   1 
ATOM   8839  C  CB  . LYS F 2 125 ? 37.572  -44.877 25.04  1   48.41  ? 106 LYS B CB  1 
ATOM   8840  C  CG  . LYS F 2 125 ? 37.332  -46.377 25.213 1   51.64  ? 106 LYS B CG  1 
ATOM   8841  C  CD  . LYS F 2 125 ? 36.41   -47     24.174 1   53.64  ? 106 LYS B CD  1 
ATOM   8842  C  CE  . LYS F 2 125 ? 36.31   -48.505 24.307 0   52.8   ? 106 LYS B CE  1 
ATOM   8843  N  NZ  . LYS F 2 125 ? 35.373  -49.078 23.312 0   52.85  ? 106 LYS B NZ  1 
ATOM   8844  N  N   . LEU F 2 126 ? 36.308  -44.547 28.361 1   43.09  ? 107 LEU B N   1 
ATOM   8845  C  CA  . LEU F 2 126 ? 36.568  -44.885 29.788 1   42.75  ? 107 LEU B CA  1 
ATOM   8846  C  C   . LEU F 2 126 ? 36.693  -46.41  29.931 1   41.17  ? 107 LEU B C   1 
ATOM   8847  O  O   . LEU F 2 126 ? 35.766  -47.13  29.493 1   39.5   ? 107 LEU B O   1 
ATOM   8848  C  CB  . LEU F 2 126 ? 35.448  -44.316 30.668 1   44.88  ? 107 LEU B CB  1 
ATOM   8849  C  CG  . LEU F 2 126 ? 35.488  -44.692 32.153 1   46.8   ? 107 LEU B CG  1 
ATOM   8850  C  CD1 . LEU F 2 126 ? 36.818  -44.326 32.791 1   47.42  ? 107 LEU B CD1 1 
ATOM   8851  C  CD2 . LEU F 2 126 ? 34.356  -44.015 32.911 1   48.13  ? 107 LEU B CD2 1 
ATOM   8852  N  N   . THR F 2 127 ? 37.807  -46.874 30.51  1   40.77  ? 108 THR B N   1 
ATOM   8853  C  CA  . THR F 2 127 ? 38.123  -48.304 30.779 1   40.95  ? 108 THR B CA  1 
ATOM   8854  C  C   . THR F 2 127 ? 38.123  -48.524 32.294 1   42.49  ? 108 THR B C   1 
ATOM   8855  O  O   . THR F 2 127 ? 38.658  -47.661 33.011 1   43.86  ? 108 THR B O   1 
ATOM   8856  C  CB  . THR F 2 127 ? 39.463  -48.696 30.138 1   40.67  ? 108 THR B CB  1 
ATOM   8857  O  OG1 . THR F 2 127 ? 39.281  -48.698 28.722 1   38.08  ? 108 THR B OG1 1 
ATOM   8858  C  CG2 . THR F 2 127 ? 39.977  -50.055 30.566 1   42.32  ? 108 THR B CG2 1 
ATOM   8859  N  N   . VAL F 2 128 ? 37.562  -49.642 32.759 1   42.5   ? 109 VAL B N   1 
ATOM   8860  C  CA  . VAL F 2 128 ? 37.635  -50.075 34.186 1   42.96  ? 109 VAL B CA  1 
ATOM   8861  C  C   . VAL F 2 128 ? 38.567  -51.294 34.256 1   44.72  ? 109 VAL B C   1 
ATOM   8862  O  O   . VAL F 2 128 ? 38.239  -52.328 33.652 1   47.66  ? 109 VAL B O   1 
ATOM   8863  C  CB  . VAL F 2 128 ? 36.227  -50.338 34.756 1   42.74  ? 109 VAL B CB  1 
ATOM   8864  C  CG1 . VAL F 2 128 ? 36.257  -50.894 36.172 1   43.17  ? 109 VAL B CG1 1 
ATOM   8865  C  CG2 . VAL F 2 128 ? 35.382  -49.075 34.715 1   42.32  ? 109 VAL B CG2 1 
ATOM   8866  N  N   . LEU F 2 129 ? 39.687  -51.166 34.97  1   45.46  ? 110 LEU B N   1 
ATOM   8867  C  CA  . LEU F 2 129 ? 40.766  -52.187 35.043 1   46.16  ? 110 LEU B CA  1 
ATOM   8868  C  C   . LEU F 2 129 ? 40.314  -53.379 35.897 1   46.17  ? 110 LEU B C   1 
ATOM   8869  O  O   . LEU F 2 129 ? 39.32   -53.247 36.63  1   46.93  ? 110 LEU B O   1 
ATOM   8870  C  CB  . LEU F 2 129 ? 42.022  -51.557 35.654 1   47.85  ? 110 LEU B CB  1 
ATOM   8871  C  CG  . LEU F 2 129 ? 42.592  -50.333 34.937 1   49.98  ? 110 LEU B CG  1 
ATOM   8872  C  CD1 . LEU F 2 129 ? 43.675  -49.679 35.782 1   51.36  ? 110 LEU B CD1 1 
ATOM   8873  C  CD2 . LEU F 2 129 ? 43.139  -50.698 33.565 1   51.29  ? 110 LEU B CD2 1 
ATOM   8874  N  N   . GLY F 2 130 ? 41.031  -54.501 35.791 1   46.79  ? 111 GLY B N   1 
ATOM   8875  C  CA  . GLY F 2 130 ? 40.955  -55.645 36.722 1   47.45  ? 111 GLY B CA  1 
ATOM   8876  C  C   . GLY F 2 130 ? 39.691  -56.479 36.576 1   46.63  ? 111 GLY B C   1 
ATOM   8877  O  O   . GLY F 2 130 ? 39.366  -57.21  37.528 1   47.56  ? 111 GLY B O   1 
ATOM   8878  N  N   . GLN F 2 131 ? 39.009  -56.411 35.432 1   46.94  ? 112 GLN B N   1 
ATOM   8879  C  CA  . GLN F 2 131 ? 37.828  -57.262 35.139 1   46.94  ? 112 GLN B CA  1 
ATOM   8880  C  C   . GLN F 2 131 ? 38.305  -58.683 34.855 1   47.44  ? 112 GLN B C   1 
ATOM   8881  O  O   . GLN F 2 131 ? 39.309  -58.872 34.168 1   48.17  ? 112 GLN B O   1 
ATOM   8882  C  CB  . GLN F 2 131 ? 37.045  -56.705 33.956 1   48.65  ? 112 GLN B CB  1 
ATOM   8883  C  CG  . GLN F 2 131 ? 36.455  -55.331 34.225 1   49.39  ? 112 GLN B CG  1 
ATOM   8884  C  CD  . GLN F 2 131 ? 35.445  -54.975 33.166 1   50.6   ? 112 GLN B CD  1 
ATOM   8885  O  OE1 . GLN F 2 131 ? 34.412  -55.63  33.031 1   53.68  ? 112 GLN B OE1 1 
ATOM   8886  N  NE2 . GLN F 2 131 ? 35.747  -53.955 32.381 1   51.62  ? 112 GLN B NE2 1 
ATOM   8887  N  N   . PRO F 2 132 ? 37.606  -59.724 35.361 1   46.6   ? 113 PRO B N   1 
ATOM   8888  C  CA  . PRO F 2 132 ? 38.096  -61.096 35.249 1   47.08  ? 113 PRO B CA  1 
ATOM   8889  C  C   . PRO F 2 132 ? 38.058  -61.619 33.807 1   47.73  ? 113 PRO B C   1 
ATOM   8890  O  O   . PRO F 2 132 ? 37.212  -61.183 33.04  1   49.68  ? 113 PRO B O   1 
ATOM   8891  C  CB  . PRO F 2 132 ? 37.141  -61.903 36.145 1   47.18  ? 113 PRO B CB  1 
ATOM   8892  C  CG  . PRO F 2 132 ? 35.861  -61.093 36.15  1   47.36  ? 113 PRO B CG  1 
ATOM   8893  C  CD  . PRO F 2 132 ? 36.302  -59.647 36.041 1   47.52  ? 113 PRO B CD  1 
ATOM   8894  N  N   . LYS F 2 133 ? 38.982  -62.526 33.482 1   48.17  ? 114 LYS B N   1 
ATOM   8895  C  CA  . LYS F 2 133 ? 38.973  -63.32  32.225 1   46.98  ? 114 LYS B CA  1 
ATOM   8896  C  C   . LYS F 2 133 ? 37.639  -64.072 32.133 1   46.21  ? 114 LYS B C   1 
ATOM   8897  O  O   . LYS F 2 133 ? 37.213  -64.658 33.148 1   46.6   ? 114 LYS B O   1 
ATOM   8898  C  CB  . LYS F 2 133 ? 40.151  -64.297 32.181 1   48.82  ? 114 LYS B CB  1 
ATOM   8899  C  CG  . LYS F 2 133 ? 40.392  -64.949 30.826 1   51.58  ? 114 LYS B CG  1 
ATOM   8900  C  CD  . LYS F 2 133 ? 41.626  -65.82  30.781 1   53.44  ? 114 LYS B CD  1 
ATOM   8901  C  CE  . LYS F 2 133 ? 41.405  -67.186 31.394 1   55.11  ? 114 LYS B CE  1 
ATOM   8902  N  NZ  . LYS F 2 133 ? 42.692  -67.863 31.671 1   56.19  ? 114 LYS B NZ  1 
ATOM   8903  N  N   . ALA F 2 134 ? 36.987  -64.004 30.97  1   44.71  ? 115 ALA B N   1 
ATOM   8904  C  CA  . ALA F 2 134 ? 35.766  -64.765 30.623 1   42.79  ? 115 ALA B CA  1 
ATOM   8905  C  C   . ALA F 2 134 ? 36.007  -65.47  29.284 1   42.54  ? 115 ALA B C   1 
ATOM   8906  O  O   . ALA F 2 134 ? 36.451  -64.792 28.34  1   43.29  ? 115 ALA B O   1 
ATOM   8907  C  CB  . ALA F 2 134 ? 34.586  -63.832 30.573 1   42.62  ? 115 ALA B CB  1 
ATOM   8908  N  N   . ALA F 2 135 ? 35.773  -66.785 29.227 1   42.59  ? 116 ALA B N   1 
ATOM   8909  C  CA  . ALA F 2 135 ? 36.034  -67.648 28.05  1   43.06  ? 116 ALA B CA  1 
ATOM   8910  C  C   . ALA F 2 135 ? 34.912  -67.473 27.033 1   43.98  ? 116 ALA B C   1 
ATOM   8911  O  O   . ALA F 2 135 ? 33.745  -67.357 27.407 1   44.43  ? 116 ALA B O   1 
ATOM   8912  C  CB  . ALA F 2 135 ? 36.15   -69.095 28.458 1   43.21  ? 116 ALA B CB  1 
ATOM   8913  N  N   . PRO F 2 136 ? 35.219  -67.493 25.716 1   42.91  ? 117 PRO B N   1 
ATOM   8914  C  CA  . PRO F 2 136 ? 34.196  -67.275 24.7   1   42.86  ? 117 PRO B CA  1 
ATOM   8915  C  C   . PRO F 2 136 ? 33.211  -68.451 24.674 1   42.96  ? 117 PRO B C   1 
ATOM   8916  O  O   . PRO F 2 136 ? 33.64   -69.574 24.808 1   46.57  ? 117 PRO B O   1 
ATOM   8917  C  CB  . PRO F 2 136 ? 34.999  -67.167 23.396 1   42.69  ? 117 PRO B CB  1 
ATOM   8918  C  CG  . PRO F 2 136 ? 36.247  -67.98  23.66  1   42.42  ? 117 PRO B CG  1 
ATOM   8919  C  CD  . PRO F 2 136 ? 36.537  -67.789 25.134 1   42.05  ? 117 PRO B CD  1 
ATOM   8920  N  N   . SER F 2 137 ? 31.919  -68.149 24.567 1   42.81  ? 118 SER B N   1 
ATOM   8921  C  CA  . SER F 2 137 ? 30.862  -69.107 24.163 1   41.6   ? 118 SER B CA  1 
ATOM   8922  C  C   . SER F 2 137 ? 30.859  -69.169 22.632 1   40.03  ? 118 SER B C   1 
ATOM   8923  O  O   . SER F 2 137 ? 30.64   -68.112 22.008 1   37.72  ? 118 SER B O   1 
ATOM   8924  C  CB  . SER F 2 137 ? 29.52   -68.713 24.725 1   41.65  ? 118 SER B CB  1 
ATOM   8925  O  OG  . SER F 2 137 ? 28.505  -69.587 24.256 1   43.8   ? 118 SER B OG  1 
ATOM   8926  N  N   . VAL F 2 138 ? 31.119  -70.353 22.064 1   38.09  ? 119 VAL B N   1 
ATOM   8927  C  CA  . VAL F 2 138 ? 31.227  -70.59  20.594 1   37.44  ? 119 VAL B CA  1 
ATOM   8928  C  C   . VAL F 2 138 ? 30.042  -71.453 20.146 1   36.99  ? 119 VAL B C   1 
ATOM   8929  O  O   . VAL F 2 138 ? 29.875  -72.56  20.688 1   37.05  ? 119 VAL B O   1 
ATOM   8930  C  CB  . VAL F 2 138 ? 32.576  -71.238 20.219 1   37.33  ? 119 VAL B CB  1 
ATOM   8931  C  CG1 . VAL F 2 138 ? 32.726  -71.392 18.714 1   37.05  ? 119 VAL B CG1 1 
ATOM   8932  C  CG2 . VAL F 2 138 ? 33.756  -70.458 20.781 1   36.93  ? 119 VAL B CG2 1 
ATOM   8933  N  N   . THR F 2 139 ? 29.258  -70.953 19.188 1   38.06  ? 120 THR B N   1 
ATOM   8934  C  CA  . THR F 2 139 ? 28.151  -71.671 18.502 1   39.37  ? 120 THR B CA  1 
ATOM   8935  C  C   . THR F 2 139 ? 28.499  -71.743 17.014 1   38.98  ? 120 THR B C   1 
ATOM   8936  O  O   . THR F 2 139 ? 28.749  -70.673 16.438 1   39.33  ? 120 THR B O   1 
ATOM   8937  C  CB  . THR F 2 139 ? 26.811  -70.957 18.73  1   41.15  ? 120 THR B CB  1 
ATOM   8938  O  OG1 . THR F 2 139 ? 26.481  -71.053 20.114 1   40.74  ? 120 THR B OG1 1 
ATOM   8939  C  CG2 . THR F 2 139 ? 25.669  -71.526 17.916 1   42.79  ? 120 THR B CG2 1 
ATOM   8940  N  N   . LEU F 2 140 ? 28.513  -72.944 16.427 1   39.35  ? 121 LEU B N   1 
ATOM   8941  C  CA  . LEU F 2 140 ? 28.818  -73.163 14.988 1   38.36  ? 121 LEU B CA  1 
ATOM   8942  C  C   . LEU F 2 140 ? 27.572  -73.705 14.281 1   37.9   ? 121 LEU B C   1 
ATOM   8943  O  O   . LEU F 2 140 ? 27.117  -74.804 14.639 1   38.46  ? 121 LEU B O   1 
ATOM   8944  C  CB  . LEU F 2 140 ? 29.994  -74.131 14.856 1   39.5   ? 121 LEU B CB  1 
ATOM   8945  C  CG  . LEU F 2 140 ? 30.436  -74.455 13.427 1   40.58  ? 121 LEU B CG  1 
ATOM   8946  C  CD1 . LEU F 2 140 ? 30.857  -73.201 12.677 1   40.11  ? 121 LEU B CD1 1 
ATOM   8947  C  CD2 . LEU F 2 140 ? 31.573  -75.464 13.438 1   41.29  ? 121 LEU B CD2 1 
ATOM   8948  N  N   . PHE F 2 141 ? 27.054  -72.953 13.309 1   38.47  ? 122 PHE B N   1 
ATOM   8949  C  CA  . PHE F 2 141 ? 25.918  -73.348 12.441 1   38.02  ? 122 PHE B CA  1 
ATOM   8950  C  C   . PHE F 2 141 ? 26.467  -73.833 11.102 1   38.28  ? 122 PHE B C   1 
ATOM   8951  O  O   . PHE F 2 141 ? 27.317  -73.17  10.515 1   36.81  ? 122 PHE B O   1 
ATOM   8952  C  CB  . PHE F 2 141 ? 24.945  -72.18  12.278 1   38.14  ? 122 PHE B CB  1 
ATOM   8953  C  CG  . PHE F 2 141 ? 24.187  -71.826 13.533 1   39.67  ? 122 PHE B CG  1 
ATOM   8954  C  CD1 . PHE F 2 141 ? 23.223  -72.683 14.046 1   39.66  ? 122 PHE B CD1 1 
ATOM   8955  C  CD2 . PHE F 2 141 ? 24.425  -70.634 14.202 1   39.88  ? 122 PHE B CD2 1 
ATOM   8956  C  CE1 . PHE F 2 141 ? 22.525  -72.363 15.203 1   40.6   ? 122 PHE B CE1 1 
ATOM   8957  C  CE2 . PHE F 2 141 ? 23.722  -70.313 15.355 1   40.1   ? 122 PHE B CE2 1 
ATOM   8958  C  CZ  . PHE F 2 141 ? 22.778  -71.18  15.857 1   40.27  ? 122 PHE B CZ  1 
ATOM   8959  N  N   . PRO F 2 142 ? 26.037  -75.013 10.595 1   39.82  ? 123 PRO B N   1 
ATOM   8960  C  CA  . PRO F 2 142 ? 26.338  -75.425 9.225  1   40.48  ? 123 PRO B CA  1 
ATOM   8961  C  C   . PRO F 2 142 ? 25.465  -74.684 8.217  1   40.93  ? 123 PRO B C   1 
ATOM   8962  O  O   . PRO F 2 142 ? 24.525  -73.99  8.607  1   42.27  ? 123 PRO B O   1 
ATOM   8963  C  CB  . PRO F 2 142 ? 26.005  -76.926 9.239  1   41.44  ? 123 PRO B CB  1 
ATOM   8964  C  CG  . PRO F 2 142 ? 24.874  -77.022 10.227 1   40.87  ? 123 PRO B CG  1 
ATOM   8965  C  CD  . PRO F 2 142 ? 25.274  -76.048 11.315 1   41.55  ? 123 PRO B CD  1 
ATOM   8966  N  N   . PRO F 2 143 ? 25.738  -74.804 6.895  1   40.92  ? 124 PRO B N   1 
ATOM   8967  C  CA  . PRO F 2 143 ? 24.866  -74.21  5.885  1   41.21  ? 124 PRO B CA  1 
ATOM   8968  C  C   . PRO F 2 143 ? 23.444  -74.783 5.986  1   42.55  ? 124 PRO B C   1 
ATOM   8969  O  O   . PRO F 2 143 ? 23.286  -75.991 6.133  1   42.34  ? 124 PRO B O   1 
ATOM   8970  C  CB  . PRO F 2 143 ? 25.532  -74.54  4.538  1   41.38  ? 124 PRO B CB  1 
ATOM   8971  C  CG  . PRO F 2 143 ? 26.5    -75.66  4.843  1   41.67  ? 124 PRO B CG  1 
ATOM   8972  C  CD  . PRO F 2 143 ? 26.897  -75.483 6.295  1   41.26  ? 124 PRO B CD  1 
ATOM   8973  N  N   . SER F 2 144 ? 22.453  -73.893 5.947  1   44.05  ? 125 SER B N   1 
ATOM   8974  C  CA  . SER F 2 144 ? 21.008  -74.23  5.93   1   44.83  ? 125 SER B CA  1 
ATOM   8975  C  C   . SER F 2 144 ? 20.678  -74.91  4.6    1   46.96  ? 125 SER B C   1 
ATOM   8976  O  O   . SER F 2 144 ? 21.354  -74.617 3.595  1   47.88  ? 125 SER B O   1 
ATOM   8977  C  CB  . SER F 2 144 ? 20.164  -72.998 6.138  1   44.24  ? 125 SER B CB  1 
ATOM   8978  O  OG  . SER F 2 144 ? 20.342  -72.065 5.081  1   43.85  ? 125 SER B OG  1 
ATOM   8979  N  N   A SER F 2 145 ? 19.671  -75.791 4.605  0.5 47.9   ? 126 SER B N   1 
ATOM   8980  N  N   B SER F 2 145 ? 19.666  -75.782 4.606  0.5 47.54  ? 126 SER B N   1 
ATOM   8981  C  CA  A SER F 2 145 ? 19.077  -76.433 3.403  0.5 47.78  ? 126 SER B CA  1 
ATOM   8982  C  CA  B SER F 2 145 ? 19.079  -76.435 3.406  0.5 47.2   ? 126 SER B CA  1 
ATOM   8983  C  C   A SER F 2 145 ? 18.67   -75.362 2.382  0.5 48.52  ? 126 SER B C   1 
ATOM   8984  C  C   B SER F 2 145 ? 18.657  -75.37  2.384  0.5 48.21  ? 126 SER B C   1 
ATOM   8985  O  O   A SER F 2 145 ? 18.884  -75.589 1.173  0.5 49.05  ? 126 SER B O   1 
ATOM   8986  O  O   B SER F 2 145 ? 18.85   -75.607 1.173  0.5 48.8   ? 126 SER B O   1 
ATOM   8987  C  CB  A SER F 2 145 ? 17.9    -77.295 3.78   0.5 47.39  ? 126 SER B CB  1 
ATOM   8988  C  CB  B SER F 2 145 ? 17.917  -77.311 3.795  0.5 46.43  ? 126 SER B CB  1 
ATOM   8989  O  OG  A SER F 2 145 ? 17.063  -77.527 2.655  0.5 46.94  ? 126 SER B OG  1 
ATOM   8990  O  OG  B SER F 2 145 ? 18.249  -78.126 4.91   0.5 45.1   ? 126 SER B OG  1 
ATOM   8991  N  N   . GLU F 2 146 ? 18.122  -74.239 2.862  1   48.9   ? 127 GLU B N   1 
ATOM   8992  C  CA  . GLU F 2 146 ? 17.622  -73.121 2.015  1   50.29  ? 127 GLU B CA  1 
ATOM   8993  C  C   . GLU F 2 146 ? 18.792  -72.489 1.248  1   47.63  ? 127 GLU B C   1 
ATOM   8994  O  O   . GLU F 2 146 ? 18.64   -72.295 0.027  1   46.39  ? 127 GLU B O   1 
ATOM   8995  C  CB  . GLU F 2 146 ? 16.861  -72.104 2.871  1   55.48  ? 127 GLU B CB  1 
ATOM   8996  C  CG  . GLU F 2 146 ? 15.679  -72.701 3.631  1   59.67  ? 127 GLU B CG  1 
ATOM   8997  C  CD  . GLU F 2 146 ? 14.637  -71.713 4.144  1   67.37  ? 127 GLU B CD  1 
ATOM   8998  O  OE1 . GLU F 2 146 ? 13.653  -72.173 4.774  1   66.07  ? 127 GLU B OE1 1 
ATOM   8999  O  OE2 . GLU F 2 146 ? 14.802  -70.484 3.917  1   70.57  ? 127 GLU B OE2 1 
ATOM   9000  N  N   . GLU F 2 147 ? 19.921  -72.221 1.92   1   45.42  ? 128 GLU B N   1 
ATOM   9001  C  CA  . GLU F 2 147 ? 21.141  -71.632 1.295  1   45.72  ? 128 GLU B CA  1 
ATOM   9002  C  C   . GLU F 2 147 ? 21.731  -72.598 0.255  1   45.81  ? 128 GLU B C   1 
ATOM   9003  O  O   . GLU F 2 147 ? 22.082  -72.122 -0.851 1   43.23  ? 128 GLU B O   1 
ATOM   9004  C  CB  . GLU F 2 147 ? 22.205  -71.28  2.335  1   44.41  ? 128 GLU B CB  1 
ATOM   9005  C  CG  . GLU F 2 147 ? 23.279  -70.357 1.779  1   42.84  ? 128 GLU B CG  1 
ATOM   9006  C  CD  . GLU F 2 147 ? 24.462  -70.078 2.688  1   42.7   ? 128 GLU B CD  1 
ATOM   9007  O  OE1 . GLU F 2 147 ? 24.617  -70.786 3.704  1   41.47  ? 128 GLU B OE1 1 
ATOM   9008  O  OE2 . GLU F 2 147 ? 25.228  -69.144 2.374  1   42.84  ? 128 GLU B OE2 1 
ATOM   9009  N  N   . LEU F 2 148 ? 21.847  -73.888 0.596  1   44.89  ? 129 LEU B N   1 
ATOM   9010  C  CA  . LEU F 2 148 ? 22.36   -74.961 -0.304 1   46.39  ? 129 LEU B CA  1 
ATOM   9011  C  C   . LEU F 2 148 ? 21.508  -75.027 -1.579 1   48.61  ? 129 LEU B C   1 
ATOM   9012  O  O   . LEU F 2 148 ? 22.101  -75.177 -2.661 1   50.66  ? 129 LEU B O   1 
ATOM   9013  C  CB  . LEU F 2 148 ? 22.351  -76.31  0.424  1   44.93  ? 129 LEU B CB  1 
ATOM   9014  C  CG  . LEU F 2 148 ? 23.307  -76.442 1.606  1   43.78  ? 129 LEU B CG  1 
ATOM   9015  C  CD1 . LEU F 2 148 ? 23.046  -77.741 2.348  1   42.68  ? 129 LEU B CD1 1 
ATOM   9016  C  CD2 . LEU F 2 148 ? 24.76   -76.36  1.165  1   45.12  ? 129 LEU B CD2 1 
ATOM   9017  N  N   . GLN F 2 149 ? 20.182  -74.901 -1.453 1   51.28  ? 130 GLN B N   1 
ATOM   9018  C  CA  . GLN F 2 149 ? 19.225  -74.891 -2.596 1   54.25  ? 130 GLN B CA  1 
ATOM   9019  C  C   . GLN F 2 149 ? 19.453  -73.663 -3.489 1   51.58  ? 130 GLN B C   1 
ATOM   9020  O  O   . GLN F 2 149 ? 19.032  -73.73  -4.659 1   52.61  ? 130 GLN B O   1 
ATOM   9021  C  CB  . GLN F 2 149 ? 17.769  -74.929 -2.119 1   59.72  ? 130 GLN B CB  1 
ATOM   9022  C  CG  . GLN F 2 149 ? 17.262  -76.333 -1.819 1   65.18  ? 130 GLN B CG  1 
ATOM   9023  C  CD  . GLN F 2 149 ? 15.796  -76.35  -1.445 1   70.94  ? 130 GLN B CD  1 
ATOM   9024  O  OE1 . GLN F 2 149 ? 14.969  -75.696 -2.079 1   75.54  ? 130 GLN B OE1 1 
ATOM   9025  N  NE2 . GLN F 2 149 ? 15.453  -77.11  -0.413 1   73.22  ? 130 GLN B NE2 1 
ATOM   9026  N  N   . ALA F 2 150 ? 20.062  -72.588 -2.968 1   49.78  ? 131 ALA B N   1 
ATOM   9027  C  CA  . ALA F 2 150 ? 20.445  -71.372 -3.729 1   48.61  ? 131 ALA B CA  1 
ATOM   9028  C  C   . ALA F 2 150 ? 21.896  -71.468 -4.241 1   48.47  ? 131 ALA B C   1 
ATOM   9029  O  O   . ALA F 2 150 ? 22.442  -70.429 -4.66  1   45.94  ? 131 ALA B O   1 
ATOM   9030  C  CB  . ALA F 2 150 ? 20.23   -70.148 -2.87  1   49.4   ? 131 ALA B CB  1 
ATOM   9031  N  N   . ASN F 2 151 ? 22.49   -72.668 -4.245 1   48.67  ? 132 ASN B N   1 
ATOM   9032  C  CA  . ASN F 2 151 ? 23.853  -72.945 -4.772 1   50.57  ? 132 ASN B CA  1 
ATOM   9033  C  C   . ASN F 2 151 ? 24.881  -72.081 -4.02  1   49.62  ? 132 ASN B C   1 
ATOM   9034  O  O   . ASN F 2 151 ? 25.766  -71.487 -4.667 1   50.28  ? 132 ASN B O   1 
ATOM   9035  C  CB  . ASN F 2 151 ? 23.915  -72.763 -6.293 1   50.45  ? 132 ASN B CB  1 
ATOM   9036  C  CG  . ASN F 2 151 ? 25.211  -73.28  -6.89  1   50.56  ? 132 ASN B CG  1 
ATOM   9037  O  OD1 . ASN F 2 151 ? 25.726  -74.319 -6.475 1   50.98  ? 132 ASN B OD1 1 
ATOM   9038  N  ND2 . ASN F 2 151 ? 25.757  -72.559 -7.856 1   50.57  ? 132 ASN B ND2 1 
ATOM   9039  N  N   . LYS F 2 152 ? 24.768  -72.032 -2.693 1   48.37  ? 133 LYS B N   1 
ATOM   9040  C  CA  . LYS F 2 152 ? 25.682  -71.274 -1.804 1   47.92  ? 133 LYS B CA  1 
ATOM   9041  C  C   . LYS F 2 152 ? 25.762  -72.013 -0.464 1   44.44  ? 133 LYS B C   1 
ATOM   9042  O  O   . LYS F 2 152 ? 24.89   -72.843 -0.204 1   46.22  ? 133 LYS B O   1 
ATOM   9043  C  CB  . LYS F 2 152 ? 25.183  -69.828 -1.698 1   52.18  ? 133 LYS B CB  1 
ATOM   9044  C  CG  . LYS F 2 152 ? 26.216  -68.765 -2.051 1   57.55  ? 133 LYS B CG  1 
ATOM   9045  C  CD  . LYS F 2 152 ? 25.649  -67.569 -2.778 1   61.54  ? 133 LYS B CD  1 
ATOM   9046  C  CE  . LYS F 2 152 ? 26.722  -66.558 -3.126 1   65.06  ? 133 LYS B CE  1 
ATOM   9047  N  NZ  . LYS F 2 152 ? 26.205  -65.49  -4.013 1   67.19  ? 133 LYS B NZ  1 
ATOM   9048  N  N   . ALA F 2 153 ? 26.791  -71.747 0.339  1   42.2   ? 134 ALA B N   1 
ATOM   9049  C  CA  . ALA F 2 153 ? 27.055  -72.451 1.617  1   39.42  ? 134 ALA B CA  1 
ATOM   9050  C  C   . ALA F 2 153 ? 27.923  -71.573 2.522  1   37.53  ? 134 ALA B C   1 
ATOM   9051  O  O   . ALA F 2 153 ? 29.018  -71.181 2.083  1   37.87  ? 134 ALA B O   1 
ATOM   9052  C  CB  . ALA F 2 153 ? 27.714  -73.781 1.346  1   38.77  ? 134 ALA B CB  1 
ATOM   9053  N  N   . THR F 2 154 ? 27.434  -71.276 3.728  1   36.14  ? 135 THR B N   1 
ATOM   9054  C  CA  . THR F 2 154 ? 28.134  -70.477 4.765  1   35.57  ? 135 THR B CA  1 
ATOM   9055  C  C   . THR F 2 154 ? 28.072  -71.227 6.097  1   35.93  ? 135 THR B C   1 
ATOM   9056  O  O   . THR F 2 154 ? 26.959  -71.63  6.484  1   37.48  ? 135 THR B O   1 
ATOM   9057  C  CB  . THR F 2 154 ? 27.508  -69.085 4.9    1   36.31  ? 135 THR B CB  1 
ATOM   9058  O  OG1 . THR F 2 154 ? 27.341  -68.519 3.599  1   35.85  ? 135 THR B OG1 1 
ATOM   9059  C  CG2 . THR F 2 154 ? 28.335  -68.154 5.76   1   36.77  ? 135 THR B CG2 1 
ATOM   9060  N  N   . LEU F 2 155 ? 29.22   -71.404 6.756  1   35.94  ? 136 LEU B N   1 
ATOM   9061  C  CA  . LEU F 2 155 ? 29.323  -71.86  8.166  1   36.74  ? 136 LEU B CA  1 
ATOM   9062  C  C   . LEU F 2 155 ? 29.433  -70.61  9.043  1   37.83  ? 136 LEU B C   1 
ATOM   9063  O  O   . LEU F 2 155 ? 30.365  -69.818 8.821  1   35.88  ? 136 LEU B O   1 
ATOM   9064  C  CB  . LEU F 2 155 ? 30.546  -72.764 8.349  1   38.86  ? 136 LEU B CB  1 
ATOM   9065  C  CG  . LEU F 2 155 ? 30.438  -74.174 7.772  1   41.05  ? 136 LEU B CG  1 
ATOM   9066  C  CD1 . LEU F 2 155 ? 30.412  -74.15  6.254  1   42.6   ? 136 LEU B CD1 1 
ATOM   9067  C  CD2 . LEU F 2 155 ? 31.594  -75.044 8.243  1   41.8   ? 136 LEU B CD2 1 
ATOM   9068  N  N   . VAL F 2 156 ? 28.5    -70.427 9.977  1   38.5   ? 137 VAL B N   1 
ATOM   9069  C  CA  . VAL F 2 156 ? 28.45   -69.248 10.887 1   38.37  ? 137 VAL B CA  1 
ATOM   9070  C  C   . VAL F 2 156 ? 29.008  -69.689 12.244 1   39     ? 137 VAL B C   1 
ATOM   9071  O  O   . VAL F 2 156 ? 28.423  -70.592 12.859 1   39.45  ? 137 VAL B O   1 
ATOM   9072  C  CB  . VAL F 2 156 ? 27.023  -68.682 10.983 1   39.24  ? 137 VAL B CB  1 
ATOM   9073  C  CG1 . VAL F 2 156 ? 26.955  -67.442 11.863 1   39.53  ? 137 VAL B CG1 1 
ATOM   9074  C  CG2 . VAL F 2 156 ? 26.449  -68.383 9.605  1   39.74  ? 137 VAL B CG2 1 
ATOM   9075  N  N   . CYS F 2 157 ? 30.129  -69.096 12.654 1   40     ? 138 CYS B N   1 
ATOM   9076  C  CA  . CYS F 2 157 ? 30.786  -69.294 13.97  1   39.54  ? 138 CYS B CA  1 
ATOM   9077  C  C   . CYS F 2 157 ? 30.568  -68.035 14.818 1   39.92  ? 138 CYS B C   1 
ATOM   9078  O  O   . CYS F 2 157 ? 31.189  -66.993 14.507 1   41.03  ? 138 CYS B O   1 
ATOM   9079  C  CB  . CYS F 2 157 ? 32.266  -69.59  13.785 1   39.71  ? 138 CYS B CB  1 
ATOM   9080  S  SG  . CYS F 2 157 ? 33.048  -70.194 15.299 1   42.58  ? 138 CYS B SG  1 
ATOM   9081  N  N   . LEU F 2 158 ? 29.688  -68.118 15.819 1   39.03  ? 139 LEU B N   1 
ATOM   9082  C  CA  . LEU F 2 158 ? 29.299  -66.981 16.695 1   40.11  ? 139 LEU B CA  1 
ATOM   9083  C  C   . LEU F 2 158 ? 30.041  -67.113 18.028 1   39.55  ? 139 LEU B C   1 
ATOM   9084  O  O   . LEU F 2 158 ? 29.992  -68.202 18.634 1   38.04  ? 139 LEU B O   1 
ATOM   9085  C  CB  . LEU F 2 158 ? 27.778  -66.969 16.877 1   42.01  ? 139 LEU B CB  1 
ATOM   9086  C  CG  . LEU F 2 158 ? 26.958  -66.885 15.587 1   43.72  ? 139 LEU B CG  1 
ATOM   9087  C  CD1 . LEU F 2 158 ? 25.472  -66.931 15.89  1   45.75  ? 139 LEU B CD1 1 
ATOM   9088  C  CD2 . LEU F 2 158 ? 27.284  -65.627 14.79  1   44.04  ? 139 LEU B CD2 1 
ATOM   9089  N  N   . ILE F 2 159 ? 30.724  -66.037 18.427 1   39.11  ? 140 ILE B N   1 
ATOM   9090  C  CA  . ILE F 2 159 ? 31.667  -65.974 19.58  1   39.04  ? 140 ILE B CA  1 
ATOM   9091  C  C   . ILE F 2 159 ? 31.207  -64.814 20.463 1   39.72  ? 140 ILE B C   1 
ATOM   9092  O  O   . ILE F 2 159 ? 31.152  -63.686 19.95  1   39.49  ? 140 ILE B O   1 
ATOM   9093  C  CB  . ILE F 2 159 ? 33.12   -65.786 19.095 1   39.85  ? 140 ILE B CB  1 
ATOM   9094  C  CG1 . ILE F 2 159 ? 33.423  -66.61  17.837 1   40.99  ? 140 ILE B CG1 1 
ATOM   9095  C  CG2 . ILE F 2 159 ? 34.097  -66.082 20.223 1   39.54  ? 140 ILE B CG2 1 
ATOM   9096  C  CD1 . ILE F 2 159 ? 34.712  -66.237 17.143 1   42.99  ? 140 ILE B CD1 1 
ATOM   9097  N  N   . SER F 2 160 ? 30.873  -65.08  21.727 1   41.35  ? 141 SER B N   1 
ATOM   9098  C  CA  . SER F 2 160 ? 30.261  -64.083 22.642 1   43.4   ? 141 SER B CA  1 
ATOM   9099  C  C   . SER F 2 160 ? 30.759  -64.268 24.074 1   44.13  ? 141 SER B C   1 
ATOM   9100  O  O   . SER F 2 160 ? 31.299  -65.345 24.389 1   43.49  ? 141 SER B O   1 
ATOM   9101  C  CB  . SER F 2 160 ? 28.76   -64.149 22.584 1   43.58  ? 141 SER B CB  1 
ATOM   9102  O  OG  . SER F 2 160 ? 28.301  -65.427 22.987 1   45.41  ? 141 SER B OG  1 
ATOM   9103  N  N   . ASP F 2 161 ? 30.573  -63.221 24.881 1   45.31  ? 142 ASP B N   1 
ATOM   9104  C  CA  . ASP F 2 161 ? 30.78   -63.195 26.351 1   46.4   ? 142 ASP B CA  1 
ATOM   9105  C  C   . ASP F 2 161 ? 32.235  -63.551 26.674 1   43.33  ? 142 ASP B C   1 
ATOM   9106  O  O   . ASP F 2 161 ? 32.45   -64.293 27.65  1   45.5   ? 142 ASP B O   1 
ATOM   9107  C  CB  . ASP F 2 161 ? 29.774  -64.11  27.06  1   49.3   ? 142 ASP B CB  1 
ATOM   9108  C  CG  . ASP F 2 161 ? 28.314  -63.802 26.759 1   53.95  ? 142 ASP B CG  1 
ATOM   9109  O  OD1 . ASP F 2 161 ? 27.994  -62.617 26.506 1   54.78  ? 142 ASP B OD1 1 
ATOM   9110  O  OD2 . ASP F 2 161 ? 27.499  -64.756 26.785 1   59.54  ? 142 ASP B OD2 1 
ATOM   9111  N  N   . PHE F 2 162 ? 33.199  -63.036 25.902 1   40.75  ? 143 PHE B N   1 
ATOM   9112  C  CA  . PHE F 2 162 ? 34.648  -63.171 26.213 1   38.99  ? 143 PHE B CA  1 
ATOM   9113  C  C   . PHE F 2 162 ? 35.199  -61.811 26.651 1   40.63  ? 143 PHE B C   1 
ATOM   9114  O  O   . PHE F 2 162 ? 34.704  -60.758 26.189 1   38.49  ? 143 PHE B O   1 
ATOM   9115  C  CB  . PHE F 2 162 ? 35.458  -63.801 25.073 1   35.99  ? 143 PHE B CB  1 
ATOM   9116  C  CG  . PHE F 2 162 ? 35.428  -63.095 23.742 1   34.82  ? 143 PHE B CG  1 
ATOM   9117  C  CD1 . PHE F 2 162 ? 34.45   -63.392 22.804 1   34.63  ? 143 PHE B CD1 1 
ATOM   9118  C  CD2 . PHE F 2 162 ? 36.401  -62.164 23.407 1   34.57  ? 143 PHE B CD2 1 
ATOM   9119  C  CE1 . PHE F 2 162 ? 34.429  -62.757 21.571 1   34.27  ? 143 PHE B CE1 1 
ATOM   9120  C  CE2 . PHE F 2 162 ? 36.38   -61.526 22.173 1   34.23  ? 143 PHE B CE2 1 
ATOM   9121  C  CZ  . PHE F 2 162 ? 35.395  -61.826 21.257 1   34.76  ? 143 PHE B CZ  1 
ATOM   9122  N  N   . TYR F 2 163 ? 36.173  -61.864 27.566 1   41.73  ? 144 TYR B N   1 
ATOM   9123  C  CA  . TYR F 2 163 ? 36.984  -60.723 28.057 1   40.89  ? 144 TYR B CA  1 
ATOM   9124  C  C   . TYR F 2 163 ? 38.382  -61.247 28.385 1   40.11  ? 144 TYR B C   1 
ATOM   9125  O  O   . TYR F 2 163 ? 38.483  -62.326 28.959 1   38.12  ? 144 TYR B O   1 
ATOM   9126  C  CB  . TYR F 2 163 ? 36.333  -60.089 29.288 1   41.39  ? 144 TYR B CB  1 
ATOM   9127  C  CG  . TYR F 2 163 ? 36.902  -58.737 29.623 1   42.14  ? 144 TYR B CG  1 
ATOM   9128  C  CD1 . TYR F 2 163 ? 38.074  -58.613 30.354 1   42.74  ? 144 TYR B CD1 1 
ATOM   9129  C  CD2 . TYR F 2 163 ? 36.305  -57.579 29.152 1   42.96  ? 144 TYR B CD2 1 
ATOM   9130  C  CE1 . TYR F 2 163 ? 38.629  -57.369 30.622 1   44.16  ? 144 TYR B CE1 1 
ATOM   9131  C  CE2 . TYR F 2 163 ? 36.842  -56.328 29.418 1   43.86  ? 144 TYR B CE2 1 
ATOM   9132  C  CZ  . TYR F 2 163 ? 38.009  -56.223 30.153 1   43.55  ? 144 TYR B CZ  1 
ATOM   9133  O  OH  . TYR F 2 163 ? 38.53   -54.993 30.421 1   44.96  ? 144 TYR B OH  1 
ATOM   9134  N  N   . PRO F 2 164 ? 39.496  -60.549 28.048 1   40.8   ? 145 PRO B N   1 
ATOM   9135  C  CA  . PRO F 2 164 ? 39.485  -59.328 27.235 1   42.01  ? 145 PRO B CA  1 
ATOM   9136  C  C   . PRO F 2 164 ? 39.128  -59.549 25.755 1   41.57  ? 145 PRO B C   1 
ATOM   9137  O  O   . PRO F 2 164 ? 39.05   -60.685 25.33  1   41.89  ? 145 PRO B O   1 
ATOM   9138  C  CB  . PRO F 2 164 ? 40.925  -58.804 27.362 1   42.03  ? 145 PRO B CB  1 
ATOM   9139  C  CG  . PRO F 2 164 ? 41.745  -60.04  27.612 1   41.17  ? 145 PRO B CG  1 
ATOM   9140  C  CD  . PRO F 2 164 ? 40.858  -60.902 28.483 1   41.27  ? 145 PRO B CD  1 
ATOM   9141  N  N   . GLY F 2 165 ? 38.922  -58.448 25.021 1   41.83  ? 146 GLY B N   1 
ATOM   9142  C  CA  . GLY F 2 165 ? 38.377  -58.424 23.648 1   42.18  ? 146 GLY B CA  1 
ATOM   9143  C  C   . GLY F 2 165 ? 39.428  -58.743 22.599 1   42.14  ? 146 GLY B C   1 
ATOM   9144  O  O   . GLY F 2 165 ? 39.727  -57.859 21.773 1   42.92  ? 146 GLY B O   1 
ATOM   9145  N  N   . ALA F 2 166 ? 39.962  -59.966 22.629 1   41.87  ? 147 ALA B N   1 
ATOM   9146  C  CA  . ALA F 2 166 ? 40.938  -60.497 21.653 1   41.47  ? 147 ALA B CA  1 
ATOM   9147  C  C   . ALA F 2 166 ? 40.745  -62.011 21.521 1   40.97  ? 147 ALA B C   1 
ATOM   9148  O  O   . ALA F 2 166 ? 40.847  -62.709 22.542 1   39.68  ? 147 ALA B O   1 
ATOM   9149  C  CB  . ALA F 2 166 ? 42.341  -60.164 22.089 1   41.29  ? 147 ALA B CB  1 
ATOM   9150  N  N   . VAL F 2 167 ? 40.463  -62.481 20.306 1   41.09  ? 148 VAL B N   1 
ATOM   9151  C  CA  . VAL F 2 167 ? 40.449  -63.926 19.935 1   41.39  ? 148 VAL B CA  1 
ATOM   9152  C  C   . VAL F 2 167 ? 41.183  -64.084 18.601 1   42.16  ? 148 VAL B C   1 
ATOM   9153  O  O   . VAL F 2 167 ? 41.247  -63.096 17.839 1   43.21  ? 148 VAL B O   1 
ATOM   9154  C  CB  . VAL F 2 167 ? 39.014  -64.485 19.855 1   40.99  ? 148 VAL B CB  1 
ATOM   9155  C  CG1 . VAL F 2 167 ? 38.342  -64.5   21.215 1   41.92  ? 148 VAL B CG1 1 
ATOM   9156  C  CG2 . VAL F 2 167 ? 38.151  -63.74  18.848 1   40.68  ? 148 VAL B CG2 1 
ATOM   9157  N  N   . THR F 2 168 ? 41.713  -65.28  18.337 1   42.47  ? 149 THR B N   1 
ATOM   9158  C  CA  . THR F 2 168 ? 42.132  -65.729 16.984 1   44.34  ? 149 THR B CA  1 
ATOM   9159  C  C   . THR F 2 168 ? 41.208  -66.88  16.579 1   43.96  ? 149 THR B C   1 
ATOM   9160  O  O   . THR F 2 168 ? 40.941  -67.751 17.437 1   45.59  ? 149 THR B O   1 
ATOM   9161  C  CB  . THR F 2 168 ? 43.622  -66.094 16.92  1   45.05  ? 149 THR B CB  1 
ATOM   9162  O  OG1 . THR F 2 168 ? 43.83   -67.31  17.636 1   49.06  ? 149 THR B OG1 1 
ATOM   9163  C  CG2 . THR F 2 168 ? 44.525  -65.015 17.477 1   45.81  ? 149 THR B CG2 1 
ATOM   9164  N  N   . VAL F 2 169 ? 40.723  -66.851 15.333 1   41.83  ? 150 VAL B N   1 
ATOM   9165  C  CA  . VAL F 2 169 ? 39.816  -67.876 14.745 1   40.92  ? 150 VAL B CA  1 
ATOM   9166  C  C   . VAL F 2 169 ? 40.589  -68.625 13.656 1   41.05  ? 150 VAL B C   1 
ATOM   9167  O  O   . VAL F 2 169 ? 41.053  -67.971 12.691 1   39.38  ? 150 VAL B O   1 
ATOM   9168  C  CB  . VAL F 2 169 ? 38.523  -67.251 14.189 1   40.77  ? 150 VAL B CB  1 
ATOM   9169  C  CG1 . VAL F 2 169 ? 37.535  -68.323 13.754 1   41.21  ? 150 VAL B CG1 1 
ATOM   9170  C  CG2 . VAL F 2 169 ? 37.869  -66.301 15.185 1   40.93  ? 150 VAL B CG2 1 
ATOM   9171  N  N   . ALA F 2 170 ? 40.744  -69.941 13.833 1   41.49  ? 151 ALA B N   1 
ATOM   9172  C  CA  . ALA F 2 170 ? 41.271  -70.882 12.819 1   40.39  ? 151 ALA B CA  1 
ATOM   9173  C  C   . ALA F 2 170 ? 40.128  -71.798 12.381 1   39.46  ? 151 ALA B C   1 
ATOM   9174  O  O   . ALA F 2 170 ? 39.361  -72.238 13.256 1   38.85  ? 151 ALA B O   1 
ATOM   9175  C  CB  . ALA F 2 170 ? 42.428  -71.669 13.372 1   40.69  ? 151 ALA B CB  1 
ATOM   9176  N  N   . TRP F 2 171 ? 40.022  -72.031 11.07  1   38.07  ? 152 TRP B N   1 
ATOM   9177  C  CA  . TRP F 2 171 ? 39.042  -72.934 10.42  1   36.76  ? 152 TRP B CA  1 
ATOM   9178  C  C   . TRP F 2 171 ? 39.762  -74.195 9.94   1   38.04  ? 152 TRP B C   1 
ATOM   9179  O  O   . TRP F 2 171 ? 40.948  -74.095 9.555  1   37.2   ? 152 TRP B O   1 
ATOM   9180  C  CB  . TRP F 2 171 ? 38.348  -72.219 9.26   1   36.46  ? 152 TRP B CB  1 
ATOM   9181  C  CG  . TRP F 2 171 ? 37.304  -71.24  9.687  1   34.71  ? 152 TRP B CG  1 
ATOM   9182  C  CD1 . TRP F 2 171 ? 37.464  -69.906 9.915  1   34.07  ? 152 TRP B CD1 1 
ATOM   9183  C  CD2 . TRP F 2 171 ? 35.919  -71.528 9.933  1   34.44  ? 152 TRP B CD2 1 
ATOM   9184  N  NE1 . TRP F 2 171 ? 36.273  -69.345 10.292 1   34.15  ? 152 TRP B NE1 1 
ATOM   9185  C  CE2 . TRP F 2 171 ? 35.307  -70.314 10.306 1   33.97  ? 152 TRP B CE2 1 
ATOM   9186  C  CE3 . TRP F 2 171 ? 35.142  -72.691 9.883  1   35.08  ? 152 TRP B CE3 1 
ATOM   9187  C  CZ2 . TRP F 2 171 ? 33.952  -70.233 10.619 1   35.15  ? 152 TRP B CZ2 1 
ATOM   9188  C  CZ3 . TRP F 2 171 ? 33.8    -72.61  10.186 1   35.38  ? 152 TRP B CZ3 1 
ATOM   9189  C  CH2 . TRP F 2 171 ? 33.217  -71.396 10.556 1   35.68  ? 152 TRP B CH2 1 
ATOM   9190  N  N   . LYS F 2 172 ? 39.06   -75.329 9.958  1   39.76  ? 153 LYS B N   1 
ATOM   9191  C  CA  . LYS F 2 172 ? 39.578  -76.64  9.493  1   42     ? 153 LYS B CA  1 
ATOM   9192  C  C   . LYS F 2 172 ? 38.541  -77.295 8.574  1   41.27  ? 153 LYS B C   1 
ATOM   9193  O  O   . LYS F 2 172 ? 37.337  -77.127 8.816  1   41.35  ? 153 LYS B O   1 
ATOM   9194  C  CB  . LYS F 2 172 ? 39.927  -77.522 10.696 1   44.48  ? 153 LYS B CB  1 
ATOM   9195  C  CG  . LYS F 2 172 ? 41.322  -77.316 11.271 1   48.19  ? 153 LYS B CG  1 
ATOM   9196  C  CD  . LYS F 2 172 ? 41.493  -77.863 12.681 1   53.36  ? 153 LYS B CD  1 
ATOM   9197  C  CE  . LYS F 2 172 ? 41.516  -79.38  12.754 1   55.88  ? 153 LYS B CE  1 
ATOM   9198  N  NZ  . LYS F 2 172 ? 40.91   -79.892 14.009 1   55.76  ? 153 LYS B NZ  1 
ATOM   9199  N  N   . ALA F 2 173 ? 39.02   -77.959 7.524  1   42.64  ? 154 ALA B N   1 
ATOM   9200  C  CA  . ALA F 2 173 ? 38.276  -78.917 6.679  1   45.39  ? 154 ALA B CA  1 
ATOM   9201  C  C   . ALA F 2 173 ? 38.907  -80.292 6.912  1   47.42  ? 154 ALA B C   1 
ATOM   9202  O  O   . ALA F 2 173 ? 40.089  -80.464 6.53   1   44.89  ? 154 ALA B O   1 
ATOM   9203  C  CB  . ALA F 2 173 ? 38.343  -78.499 5.229  1   45.48  ? 154 ALA B CB  1 
ATOM   9204  N  N   . ASP F 2 174 ? 38.168  -81.201 7.561  1   49.36  ? 155 ASP B N   1 
ATOM   9205  C  CA  . ASP F 2 174 ? 38.703  -82.459 8.151  1   51.32  ? 155 ASP B CA  1 
ATOM   9206  C  C   . ASP F 2 174 ? 39.783  -82.056 9.169  1   52.69  ? 155 ASP B C   1 
ATOM   9207  O  O   . ASP F 2 174 ? 39.438  -81.296 10.087 1   54.79  ? 155 ASP B O   1 
ATOM   9208  C  CB  . ASP F 2 174 ? 39.143  -83.43  7.049  1   52.09  ? 155 ASP B CB  1 
ATOM   9209  C  CG  . ASP F 2 174 ? 38.061  -83.749 6.028  1   53.7   ? 155 ASP B CG  1 
ATOM   9210  O  OD1 . ASP F 2 174 ? 36.873  -83.803 6.416  1   55.68  ? 155 ASP B OD1 1 
ATOM   9211  O  OD2 . ASP F 2 174 ? 38.416  -83.95  4.848  1   55.15  ? 155 ASP B OD2 1 
ATOM   9212  N  N   . SER F 2 175 ? 41.034  -82.498 9.007  1   53.87  ? 156 SER B N   1 
ATOM   9213  C  CA  . SER F 2 175 ? 42.186  -82.103 9.864  1   56.71  ? 156 SER B CA  1 
ATOM   9214  C  C   . SER F 2 175 ? 43.028  -81.002 9.191  1   55.16  ? 156 SER B C   1 
ATOM   9215  O  O   . SER F 2 175 ? 43.933  -80.465 9.861  1   54.99  ? 156 SER B O   1 
ATOM   9216  C  CB  . SER F 2 175 ? 43.017  -83.314 10.211 1   58.94  ? 156 SER B CB  1 
ATOM   9217  O  OG  . SER F 2 175 ? 43.292  -84.088 9.051  1   62.67  ? 156 SER B OG  1 
ATOM   9218  N  N   . SER F 2 176 ? 42.748  -80.663 7.928  1   54.55  ? 157 SER B N   1 
ATOM   9219  C  CA  . SER F 2 176 ? 43.508  -79.666 7.128  1   53.66  ? 157 SER B CA  1 
ATOM   9220  C  C   . SER F 2 176 ? 43.011  -78.261 7.46   1   51.28  ? 157 SER B C   1 
ATOM   9221  O  O   . SER F 2 176 ? 41.808  -78.013 7.409  1   50.7   ? 157 SER B O   1 
ATOM   9222  C  CB  . SER F 2 176 ? 43.386  -79.941 5.644  1   56.76  ? 157 SER B CB  1 
ATOM   9223  O  OG  . SER F 2 176 ? 43.958  -81.196 5.304  1   58.69  ? 157 SER B OG  1 
ATOM   9224  N  N   . PRO F 2 177 ? 43.896  -77.292 7.798  1   47.99  ? 158 PRO B N   1 
ATOM   9225  C  CA  . PRO F 2 177 ? 43.458  -75.918 8.032  1   47.08  ? 158 PRO B CA  1 
ATOM   9226  C  C   . PRO F 2 177 ? 42.977  -75.232 6.743  1   44.79  ? 158 PRO B C   1 
ATOM   9227  O  O   . PRO F 2 177 ? 43.409  -75.619 5.677  1   43.42  ? 158 PRO B O   1 
ATOM   9228  C  CB  . PRO F 2 177 ? 44.695  -75.223 8.625  1   45.89  ? 158 PRO B CB  1 
ATOM   9229  C  CG  . PRO F 2 177 ? 45.864  -76.045 8.151  1   44.99  ? 158 PRO B CG  1 
ATOM   9230  C  CD  . PRO F 2 177 ? 45.344  -77.456 8.001  1   46.33  ? 158 PRO B CD  1 
ATOM   9231  N  N   . VAL F 2 178 ? 42.073  -74.26  6.892  1   43.63  ? 159 VAL B N   1 
ATOM   9232  C  CA  . VAL F 2 178 ? 41.488  -73.431 5.798  1   43.3   ? 159 VAL B CA  1 
ATOM   9233  C  C   . VAL F 2 178 ? 41.634  -71.961 6.198  1   40.69  ? 159 VAL B C   1 
ATOM   9234  O  O   . VAL F 2 178 ? 41.315  -71.633 7.362  1   42     ? 159 VAL B O   1 
ATOM   9235  C  CB  . VAL F 2 178 ? 40.011  -73.784 5.533  1   47.13  ? 159 VAL B CB  1 
ATOM   9236  C  CG1 . VAL F 2 178 ? 39.512  -73.191 4.219  1   47.03  ? 159 VAL B CG1 1 
ATOM   9237  C  CG2 . VAL F 2 178 ? 39.764  -75.283 5.555  1   47.78  ? 159 VAL B CG2 1 
ATOM   9238  N  N   . LYS F 2 179 ? 42.117  -71.127 5.273  1   39.68  ? 160 LYS B N   1 
ATOM   9239  C  CA  . LYS F 2 179 ? 42.282  -69.655 5.447  1   39.68  ? 160 LYS B CA  1 
ATOM   9240  C  C   . LYS F 2 179 ? 41.441  -68.894 4.407  1   37.53  ? 160 LYS B C   1 
ATOM   9241  O  O   . LYS F 2 179 ? 40.974  -67.786 4.735  1   38.07  ? 160 LYS B O   1 
ATOM   9242  C  CB  . LYS F 2 179 ? 43.772  -69.299 5.381  1   40.61  ? 160 LYS B CB  1 
ATOM   9243  C  CG  . LYS F 2 179 ? 44.623  -69.891 6.499  1   41.4   ? 160 LYS B CG  1 
ATOM   9244  C  CD  . LYS F 2 179 ? 46.057  -69.396 6.521  1   43.83  ? 160 LYS B CD  1 
ATOM   9245  C  CE  . LYS F 2 179 ? 46.913  -70.052 7.588  1   44.73  ? 160 LYS B CE  1 
ATOM   9246  N  NZ  . LYS F 2 179 ? 48.32   -69.61  7.514  0   43.07  ? 160 LYS B NZ  1 
ATOM   9247  N  N   . ALA F 2 180 ? 41.251  -69.459 3.21   1   36.48  ? 161 ALA B N   1 
ATOM   9248  C  CA  . ALA F 2 180 ? 40.437  -68.89  2.108  1   36.1   ? 161 ALA B CA  1 
ATOM   9249  C  C   . ALA F 2 180 ? 38.947  -68.933 2.461  1   35.44  ? 161 ALA B C   1 
ATOM   9250  O  O   . ALA F 2 180 ? 38.498  -69.929 3.047  1   35.99  ? 161 ALA B O   1 
ATOM   9251  C  CB  . ALA F 2 180 ? 40.697  -69.642 0.827  1   35.99  ? 161 ALA B CB  1 
ATOM   9252  N  N   . GLY F 2 181 ? 38.206  -67.889 2.088  1   35.36  ? 162 GLY B N   1 
ATOM   9253  C  CA  . GLY F 2 181 ? 36.751  -67.79  2.311  1   35.93  ? 162 GLY B CA  1 
ATOM   9254  C  C   . GLY F 2 181 ? 36.396  -67.506 3.762  1   36.12  ? 162 GLY B C   1 
ATOM   9255  O  O   . GLY F 2 181 ? 35.203  -67.628 4.086  1   36.79  ? 162 GLY B O   1 
ATOM   9256  N  N   . VAL F 2 182 ? 37.376  -67.116 4.59   1   35.88  ? 163 VAL B N   1 
ATOM   9257  C  CA  . VAL F 2 182 ? 37.204  -66.741 6.024  1   36.55  ? 163 VAL B CA  1 
ATOM   9258  C  C   . VAL F 2 182 ? 37.039  -65.217 6.101  1   40.17  ? 163 VAL B C   1 
ATOM   9259  O  O   . VAL F 2 182 ? 37.916  -64.5   5.581  1   41.34  ? 163 VAL B O   1 
ATOM   9260  C  CB  . VAL F 2 182 ? 38.395  -67.22  6.874  1   35.7   ? 163 VAL B CB  1 
ATOM   9261  C  CG1 . VAL F 2 182 ? 38.286  -66.783 8.33   1   35.55  ? 163 VAL B CG1 1 
ATOM   9262  C  CG2 . VAL F 2 182 ? 38.574  -68.727 6.793  1   36.07  ? 163 VAL B CG2 1 
ATOM   9263  N  N   . GLU F 2 183 ? 35.946  -64.746 6.708  1   42.9   ? 164 GLU B N   1 
ATOM   9264  C  CA  . GLU F 2 183 ? 35.729  -63.318 7.063  1   45.62  ? 164 GLU B CA  1 
ATOM   9265  C  C   . GLU F 2 183 ? 35.417  -63.274 8.564  1   43.84  ? 164 GLU B C   1 
ATOM   9266  O  O   . GLU F 2 183 ? 34.334  -63.748 8.949  1   44.14  ? 164 GLU B O   1 
ATOM   9267  C  CB  . GLU F 2 183 ? 34.602  -62.698 6.228  1   49.87  ? 164 GLU B CB  1 
ATOM   9268  C  CG  . GLU F 2 183 ? 34.662  -62.994 4.733  1   53.72  ? 164 GLU B CG  1 
ATOM   9269  C  CD  . GLU F 2 183 ? 35.506  -62.061 3.878  1   57.41  ? 164 GLU B CD  1 
ATOM   9270  O  OE1 . GLU F 2 183 ? 36.316  -61.286 4.441  1   60.86  ? 164 GLU B OE1 1 
ATOM   9271  O  OE2 . GLU F 2 183 ? 35.342  -62.105 2.636  1   58     ? 164 GLU B OE2 1 
ATOM   9272  N  N   . THR F 2 184 ? 36.362  -62.785 9.375  1   42.15  ? 165 THR B N   1 
ATOM   9273  C  CA  . THR F 2 184 ? 36.24   -62.605 10.848 1   39.83  ? 165 THR B CA  1 
ATOM   9274  C  C   . THR F 2 184 ? 36.074  -61.114 11.165 1   39.07  ? 165 THR B C   1 
ATOM   9275  O  O   . THR F 2 184 ? 36.827  -60.304 10.589 1   38.95  ? 165 THR B O   1 
ATOM   9276  C  CB  . THR F 2 184 ? 37.46   -63.172 11.583 1   37.64  ? 165 THR B CB  1 
ATOM   9277  O  OG1 . THR F 2 184 ? 37.719  -64.487 11.095 1   38.47  ? 165 THR B OG1 1 
ATOM   9278  C  CG2 . THR F 2 184 ? 37.269  -63.236 13.08  1   38.46  ? 165 THR B CG2 1 
ATOM   9279  N  N   . THR F 2 185 ? 35.143  -60.778 12.065 1   38.2   ? 166 THR B N   1 
ATOM   9280  C  CA  . THR F 2 185 ? 34.919  -59.401 12.584 1   38.53  ? 166 THR B CA  1 
ATOM   9281  C  C   . THR F 2 185 ? 35.972  -59.073 13.65  1   40.84  ? 166 THR B C   1 
ATOM   9282  O  O   . THR F 2 185 ? 36.483  -60.01  14.318 1   39.26  ? 166 THR B O   1 
ATOM   9283  C  CB  . THR F 2 185 ? 33.516  -59.232 13.185 1   36.7   ? 166 THR B CB  1 
ATOM   9284  O  OG1 . THR F 2 185 ? 33.398  -60.084 14.324 1   34.61  ? 166 THR B OG1 1 
ATOM   9285  C  CG2 . THR F 2 185 ? 32.402  -59.544 12.209 1   36.98  ? 166 THR B CG2 1 
ATOM   9286  N  N   . THR F 2 186 ? 36.277  -57.787 13.825 1   43.52  ? 167 THR B N   1 
ATOM   9287  C  CA  . THR F 2 186 ? 36.985  -57.281 15.03  1   46.93  ? 167 THR B CA  1 
ATOM   9288  C  C   . THR F 2 186 ? 36.022  -57.444 16.2   1   46.67  ? 167 THR B C   1 
ATOM   9289  O  O   . THR F 2 186 ? 34.82   -57.268 16.023 1   48.4   ? 167 THR B O   1 
ATOM   9290  C  CB  . THR F 2 186 ? 37.465  -55.833 14.869 1   48.45  ? 167 THR B CB  1 
ATOM   9291  O  OG1 . THR F 2 186 ? 36.369  -55.077 14.355 1   53.08  ? 167 THR B OG1 1 
ATOM   9292  C  CG2 . THR F 2 186 ? 38.664  -55.702 13.956 1   48.61  ? 167 THR B CG2 1 
ATOM   9293  N  N   . PRO F 2 187 ? 36.495  -57.815 17.411 1   47.79  ? 168 PRO B N   1 
ATOM   9294  C  CA  . PRO F 2 187 ? 35.603  -57.959 18.557 1   47.82  ? 168 PRO B CA  1 
ATOM   9295  C  C   . PRO F 2 187 ? 35.005  -56.591 18.907 1   47.33  ? 168 PRO B C   1 
ATOM   9296  O  O   . PRO F 2 187 ? 35.712  -55.608 18.791 1   48.14  ? 168 PRO B O   1 
ATOM   9297  C  CB  . PRO F 2 187 ? 36.494  -58.518 19.676 1   49.74  ? 168 PRO B CB  1 
ATOM   9298  C  CG  . PRO F 2 187 ? 37.906  -58.149 19.264 1   51.65  ? 168 PRO B CG  1 
ATOM   9299  C  CD  . PRO F 2 187 ? 37.899  -58.092 17.751 1   50     ? 168 PRO B CD  1 
ATOM   9300  N  N   . SER F 2 188 ? 33.718  -56.559 19.259 1   46.52  ? 169 SER B N   1 
ATOM   9301  C  CA  . SER F 2 188 ? 32.982  -55.329 19.645 1   47.27  ? 169 SER B CA  1 
ATOM   9302  C  C   . SER F 2 188 ? 32.39   -55.513 21.042 1   47.26  ? 169 SER B C   1 
ATOM   9303  O  O   . SER F 2 188 ? 31.999  -56.654 21.378 1   45.37  ? 169 SER B O   1 
ATOM   9304  C  CB  . SER F 2 188 ? 31.923  -54.989 18.641 1   48.28  ? 169 SER B CB  1 
ATOM   9305  O  OG  . SER F 2 188 ? 30.948  -56.014 18.598 1   52.02  ? 169 SER B OG  1 
ATOM   9306  N  N   . LYS F 2 189 ? 32.322  -54.414 21.797 1   47.57  ? 170 LYS B N   1 
ATOM   9307  C  CA  . LYS F 2 189 ? 31.839  -54.358 23.2   1   49.63  ? 170 LYS B CA  1 
ATOM   9308  C  C   . LYS F 2 189 ? 30.349  -54.716 23.22  1   49.08  ? 170 LYS B C   1 
ATOM   9309  O  O   . LYS F 2 189 ? 29.596  -54.125 22.432 1   49.49  ? 170 LYS B O   1 
ATOM   9310  C  CB  . LYS F 2 189 ? 32.092  -52.958 23.772 1   52.05  ? 170 LYS B CB  1 
ATOM   9311  C  CG  . LYS F 2 189 ? 32.098  -52.85  25.291 1   54.4   ? 170 LYS B CG  1 
ATOM   9312  C  CD  . LYS F 2 189 ? 33.351  -53.409 25.929 1   56.94  ? 170 LYS B CD  1 
ATOM   9313  C  CE  . LYS F 2 189 ? 33.66   -52.793 27.277 1   58.65  ? 170 LYS B CE  1 
ATOM   9314  N  NZ  . LYS F 2 189 ? 34.893  -53.378 27.852 1   62.08  ? 170 LYS B NZ  1 
ATOM   9315  N  N   . GLN F 2 190 ? 29.954  -55.666 24.07  1   50.67  ? 171 GLN B N   1 
ATOM   9316  C  CA  . GLN F 2 190 ? 28.532  -55.993 24.363 1   53.98  ? 171 GLN B CA  1 
ATOM   9317  C  C   . GLN F 2 190 ? 28.014  -55.036 25.446 1   56.06  ? 171 GLN B C   1 
ATOM   9318  O  O   . GLN F 2 190 ? 28.828  -54.275 26.006 1   59.86  ? 171 GLN B O   1 
ATOM   9319  C  CB  . GLN F 2 190 ? 28.392  -57.434 24.856 1   53.04  ? 171 GLN B CB  1 
ATOM   9320  C  CG  . GLN F 2 190 ? 28.933  -58.489 23.897 1   52.09  ? 171 GLN B CG  1 
ATOM   9321  C  CD  . GLN F 2 190 ? 28.778  -59.911 24.387 1   52.6   ? 171 GLN B CD  1 
ATOM   9322  O  OE1 . GLN F 2 190 ? 28.778  -60.849 23.6   1   54.2   ? 171 GLN B OE1 1 
ATOM   9323  N  NE2 . GLN F 2 190 ? 28.66   -60.108 25.691 1   54.1   ? 171 GLN B NE2 1 
ATOM   9324  N  N   . SER F 2 191 ? 26.719  -55.11  25.765 1   58.19  ? 172 SER B N   1 
ATOM   9325  C  CA  . SER F 2 191 ? 26.064  -54.324 26.846 1   60.75  ? 172 SER B CA  1 
ATOM   9326  C  C   . SER F 2 191 ? 26.566  -54.751 28.236 1   60.51  ? 172 SER B C   1 
ATOM   9327  O  O   . SER F 2 191 ? 26.435  -53.931 29.162 1   63.71  ? 172 SER B O   1 
ATOM   9328  C  CB  . SER F 2 191 ? 24.568  -54.433 26.764 1   62.71  ? 172 SER B CB  1 
ATOM   9329  O  OG  . SER F 2 191 ? 24.136  -55.729 27.148 1   67.37  ? 172 SER B OG  1 
ATOM   9330  N  N   . ASN F 2 192 ? 27.104  -55.972 28.382 1   60.5   ? 173 ASN B N   1 
ATOM   9331  C  CA  . ASN F 2 192 ? 27.55   -56.558 29.681 1   60.32  ? 173 ASN B CA  1 
ATOM   9332  C  C   . ASN F 2 192 ? 29.074  -56.426 29.87  1   59.91  ? 173 ASN B C   1 
ATOM   9333  O  O   . ASN F 2 192 ? 29.6    -57.133 30.754 1   60.27  ? 173 ASN B O   1 
ATOM   9334  C  CB  . ASN F 2 192 ? 27.062  -58.008 29.824 1   60.37  ? 173 ASN B CB  1 
ATOM   9335  C  CG  . ASN F 2 192 ? 27.748  -59.011 28.915 1   60.96  ? 173 ASN B CG  1 
ATOM   9336  O  OD1 . ASN F 2 192 ? 28.57   -58.652 28.073 1   59.99  ? 173 ASN B OD1 1 
ATOM   9337  N  ND2 . ASN F 2 192 ? 27.415  -60.282 29.079 1   60.53  ? 173 ASN B ND2 1 
ATOM   9338  N  N   . ASN F 2 193 ? 29.757  -55.595 29.064 1   60.12  ? 174 ASN B N   1 
ATOM   9339  C  CA  . ASN F 2 193 ? 31.21   -55.256 29.142 1   57.62  ? 174 ASN B CA  1 
ATOM   9340  C  C   . ASN F 2 193 ? 32.095  -56.319 28.481 1   56.14  ? 174 ASN B C   1 
ATOM   9341  O  O   . ASN F 2 193 ? 33.261  -55.981 28.197 1   58.62  ? 174 ASN B O   1 
ATOM   9342  C  CB  . ASN F 2 193 ? 31.71   -55.012 30.568 1   58.58  ? 174 ASN B CB  1 
ATOM   9343  C  CG  . ASN F 2 193 ? 31.047  -53.815 31.207 1   58.49  ? 174 ASN B CG  1 
ATOM   9344  O  OD1 . ASN F 2 193 ? 30.322  -53.949 32.192 1   57.02  ? 174 ASN B OD1 1 
ATOM   9345  N  ND2 . ASN F 2 193 ? 31.274  -52.647 30.631 1   58.01  ? 174 ASN B ND2 1 
ATOM   9346  N  N   . LYS F 2 194 ? 31.595  -57.539 28.252 1   54.41  ? 175 LYS B N   1 
ATOM   9347  C  CA  . LYS F 2 194 ? 32.324  -58.607 27.515 1   53.12  ? 175 LYS B CA  1 
ATOM   9348  C  C   . LYS F 2 194 ? 32.188  -58.325 26.012 1   50.47  ? 175 LYS B C   1 
ATOM   9349  O  O   . LYS F 2 194 ? 31.475  -57.367 25.653 1   51.97  ? 175 LYS B O   1 
ATOM   9350  C  CB  . LYS F 2 194 ? 31.801  -59.989 27.922 1   55.42  ? 175 LYS B CB  1 
ATOM   9351  C  CG  . LYS F 2 194 ? 31.783  -60.261 29.423 1   57.91  ? 175 LYS B CG  1 
ATOM   9352  C  CD  . LYS F 2 194 ? 31.527  -61.72  29.774 1   61.1   ? 175 LYS B CD  1 
ATOM   9353  C  CE  . LYS F 2 194 ? 30.574  -61.922 30.936 1   63.79  ? 175 LYS B CE  1 
ATOM   9354  N  NZ  . LYS F 2 194 ? 31.152  -61.458 32.219 1   66.03  ? 175 LYS B NZ  1 
ATOM   9355  N  N   . TYR F 2 195 ? 32.858  -59.114 25.167 1   48.56  ? 176 TYR B N   1 
ATOM   9356  C  CA  . TYR F 2 195 ? 33.022  -58.854 23.71  1   45.05  ? 176 TYR B CA  1 
ATOM   9357  C  C   . TYR F 2 195 ? 32.35   -59.96  22.893 1   41.92  ? 176 TYR B C   1 
ATOM   9358  O  O   . TYR F 2 195 ? 32.27   -61.107 23.37  1   42.62  ? 176 TYR B O   1 
ATOM   9359  C  CB  . TYR F 2 195 ? 34.504  -58.725 23.357 1   44.97  ? 176 TYR B CB  1 
ATOM   9360  C  CG  . TYR F 2 195 ? 35.144  -57.47  23.89  1   44.95  ? 176 TYR B CG  1 
ATOM   9361  C  CD1 . TYR F 2 195 ? 35.566  -57.392 25.205 1   45.95  ? 176 TYR B CD1 1 
ATOM   9362  C  CD2 . TYR F 2 195 ? 35.311  -56.351 23.088 1   46.53  ? 176 TYR B CD2 1 
ATOM   9363  C  CE1 . TYR F 2 195 ? 36.144  -56.239 25.71  1   48.19  ? 176 TYR B CE1 1 
ATOM   9364  C  CE2 . TYR F 2 195 ? 35.893  -55.191 23.575 1   46.9   ? 176 TYR B CE2 1 
ATOM   9365  C  CZ  . TYR F 2 195 ? 36.309  -55.134 24.894 1   48.46  ? 176 TYR B CZ  1 
ATOM   9366  O  OH  . TYR F 2 195 ? 36.883  -54.001 25.397 1   48.45  ? 176 TYR B OH  1 
ATOM   9367  N  N   . ALA F 2 196 ? 31.873  -59.599 21.699 1   38.84  ? 177 ALA B N   1 
ATOM   9368  C  CA  . ALA F 2 196 ? 31.281  -60.511 20.695 1   37.43  ? 177 ALA B CA  1 
ATOM   9369  C  C   . ALA F 2 196 ? 32.089  -60.416 19.401 1   38.08  ? 177 ALA B C   1 
ATOM   9370  O  O   . ALA F 2 196 ? 32.581  -59.316 19.089 1   38.68  ? 177 ALA B O   1 
ATOM   9371  C  CB  . ALA F 2 196 ? 29.839  -60.157 20.45  1   36.4   ? 177 ALA B CB  1 
ATOM   9372  N  N   . ALA F 2 197 ? 32.222  -61.534 18.687 1   38.08  ? 178 ALA B N   1 
ATOM   9373  C  CA  . ALA F 2 197 ? 32.798  -61.599 17.325 1   39.09  ? 178 ALA B CA  1 
ATOM   9374  C  C   . ALA F 2 197 ? 32.155  -62.757 16.565 1   38.45  ? 178 ALA B C   1 
ATOM   9375  O  O   . ALA F 2 197 ? 31.8    -63.756 17.205 1   39.23  ? 178 ALA B O   1 
ATOM   9376  C  CB  . ALA F 2 197 ? 34.298  -61.748 17.399 1   40.56  ? 178 ALA B CB  1 
ATOM   9377  N  N   . SER F 2 198 ? 31.979  -62.604 15.253 1   38.9   ? 179 SER B N   1 
ATOM   9378  C  CA  . SER F 2 198 ? 31.495  -63.676 14.345 1   39.01  ? 179 SER B CA  1 
ATOM   9379  C  C   . SER F 2 198 ? 32.601  -64.022 13.346 1   39.45  ? 179 SER B C   1 
ATOM   9380  O  O   . SER F 2 198 ? 33.48   -63.168 13.093 1   39.65  ? 179 SER B O   1 
ATOM   9381  C  CB  . SER F 2 198 ? 30.202  -63.301 13.661 1   38.98  ? 179 SER B CB  1 
ATOM   9382  O  OG  . SER F 2 198 ? 30.119  -61.906 13.414 1   39.11  ? 179 SER B OG  1 
ATOM   9383  N  N   . SER F 2 199 ? 32.588  -65.252 12.84  1   39.22  ? 180 SER B N   1 
ATOM   9384  C  CA  . SER F 2 199 ? 33.446  -65.682 11.71  1   40.02  ? 180 SER B CA  1 
ATOM   9385  C  C   . SER F 2 199 ? 32.613  -66.52  10.74  1   40.12  ? 180 SER B C   1 
ATOM   9386  O  O   . SER F 2 199 ? 31.832  -67.362 11.215 1   41.76  ? 180 SER B O   1 
ATOM   9387  C  CB  . SER F 2 199 ? 34.663  -66.407 12.187 1   40.09  ? 180 SER B CB  1 
ATOM   9388  O  OG  . SER F 2 199 ? 35.673  -66.363 11.191 1   41.46  ? 180 SER B OG  1 
ATOM   9389  N  N   . TYR F 2 200 ? 32.769  -66.262 9.439  1   39.2   ? 181 TYR B N   1 
ATOM   9390  C  CA  . TYR F 2 200 ? 31.993  -66.876 8.332  1   39.2   ? 181 TYR B CA  1 
ATOM   9391  C  C   . TYR F 2 200 ? 32.958  -67.61  7.395  1   37.86  ? 181 TYR B C   1 
ATOM   9392  O  O   . TYR F 2 200 ? 33.932  -66.978 6.96   1   38.71  ? 181 TYR B O   1 
ATOM   9393  C  CB  . TYR F 2 200 ? 31.207  -65.79  7.595  1   40.35  ? 181 TYR B CB  1 
ATOM   9394  C  CG  . TYR F 2 200 ? 30.21   -65.056 8.452  1   41.31  ? 181 TYR B CG  1 
ATOM   9395  C  CD1 . TYR F 2 200 ? 30.593  -63.975 9.231  1   42.55  ? 181 TYR B CD1 1 
ATOM   9396  C  CD2 . TYR F 2 200 ? 28.882  -65.448 8.495  1   41.86  ? 181 TYR B CD2 1 
ATOM   9397  C  CE1 . TYR F 2 200 ? 29.684  -63.295 10.026 1   41.97  ? 181 TYR B CE1 1 
ATOM   9398  C  CE2 . TYR F 2 200 ? 27.959  -64.778 9.284  1   42.98  ? 181 TYR B CE2 1 
ATOM   9399  C  CZ  . TYR F 2 200 ? 28.361  -63.7   10.053 1   42.94  ? 181 TYR B CZ  1 
ATOM   9400  O  OH  . TYR F 2 200 ? 27.456  -63.043 10.836 1   46.46  ? 181 TYR B OH  1 
ATOM   9401  N  N   . LEU F 2 201 ? 32.708  -68.893 7.116  1   37.4   ? 182 LEU B N   1 
ATOM   9402  C  CA  . LEU F 2 201 ? 33.453  -69.688 6.101  1   37.7   ? 182 LEU B CA  1 
ATOM   9403  C  C   . LEU F 2 201 ? 32.538  -69.915 4.892  1   38.12  ? 182 LEU B C   1 
ATOM   9404  O  O   . LEU F 2 201 ? 31.58   -70.689 5.03   1   38.52  ? 182 LEU B O   1 
ATOM   9405  C  CB  . LEU F 2 201 ? 33.928  -71.015 6.707  1   37.63  ? 182 LEU B CB  1 
ATOM   9406  C  CG  . LEU F 2 201 ? 34.781  -71.897 5.789  1   37.48  ? 182 LEU B CG  1 
ATOM   9407  C  CD1 . LEU F 2 201 ? 36.126  -71.249 5.489  1   38.81  ? 182 LEU B CD1 1 
ATOM   9408  C  CD2 . LEU F 2 201 ? 34.993  -73.278 6.39   1   36.8   ? 182 LEU B CD2 1 
ATOM   9409  N  N   . SER F 2 202 ? 32.821  -69.242 3.768  1   39.25  ? 183 SER B N   1 
ATOM   9410  C  CA  . SER F 2 202 ? 32.183  -69.479 2.445  1   39.16  ? 183 SER B CA  1 
ATOM   9411  C  C   . SER F 2 202 ? 32.748  -70.766 1.839  1   37.69  ? 183 SER B C   1 
ATOM   9412  O  O   . SER F 2 202 ? 33.981  -70.871 1.704  1   38.2   ? 183 SER B O   1 
ATOM   9413  C  CB  . SER F 2 202 ? 32.387  -68.326 1.497  1   39.85  ? 183 SER B CB  1 
ATOM   9414  O  OG  . SER F 2 202 ? 31.866  -67.125 2.034  1   43.64  ? 183 SER B OG  1 
ATOM   9415  N  N   . LEU F 2 203 ? 31.866  -71.706 1.512  1   37.46  ? 184 LEU B N   1 
ATOM   9416  C  CA  . LEU F 2 203 ? 32.159  -72.9   0.684  1   37.17  ? 184 LEU B CA  1 
ATOM   9417  C  C   . LEU F 2 203 ? 31.16   -72.92  -0.474 1   36.32  ? 184 LEU B C   1 
ATOM   9418  O  O   . LEU F 2 203 ? 30.163  -72.169 -0.417 1   37.76  ? 184 LEU B O   1 
ATOM   9419  C  CB  . LEU F 2 203 ? 32.013  -74.16  1.54   1   39.26  ? 184 LEU B CB  1 
ATOM   9420  C  CG  . LEU F 2 203 ? 32.82   -74.203 2.838  1   41.29  ? 184 LEU B CG  1 
ATOM   9421  C  CD1 . LEU F 2 203 ? 32.362  -75.368 3.699  1   42.28  ? 184 LEU B CD1 1 
ATOM   9422  C  CD2 . LEU F 2 203 ? 34.312  -74.315 2.56   1   42.2   ? 184 LEU B CD2 1 
ATOM   9423  N  N   . THR F 2 204 ? 31.418  -73.736 -1.491 1   34.62  ? 185 THR B N   1 
ATOM   9424  C  CA  . THR F 2 204 ? 30.392  -74.159 -2.474 1   34.93  ? 185 THR B CA  1 
ATOM   9425  C  C   . THR F 2 204 ? 29.631  -75.321 -1.841 1   34.54  ? 185 THR B C   1 
ATOM   9426  O  O   . THR F 2 204 ? 30.165  -75.997 -0.962 1   34.25  ? 185 THR B O   1 
ATOM   9427  C  CB  . THR F 2 204 ? 31.023  -74.524 -3.822 1   35.31  ? 185 THR B CB  1 
ATOM   9428  O  OG1 . THR F 2 204 ? 31.864  -75.661 -3.613 1   37.31  ? 185 THR B OG1 1 
ATOM   9429  C  CG2 . THR F 2 204 ? 31.816  -73.386 -4.425 1   34.39  ? 185 THR B CG2 1 
ATOM   9430  N  N   . PRO F 2 205 ? 28.366  -75.585 -2.236 1   34.82  ? 186 PRO B N   1 
ATOM   9431  C  CA  . PRO F 2 205 ? 27.669  -76.792 -1.79  1   36.59  ? 186 PRO B CA  1 
ATOM   9432  C  C   . PRO F 2 205 ? 28.505  -78.065 -1.988 1   38.99  ? 186 PRO B C   1 
ATOM   9433  O  O   . PRO F 2 205 ? 28.528  -78.895 -1.097 1   41.25  ? 186 PRO B O   1 
ATOM   9434  C  CB  . PRO F 2 205 ? 26.422  -76.819 -2.678 1   36.34  ? 186 PRO B CB  1 
ATOM   9435  C  CG  . PRO F 2 205 ? 26.16   -75.361 -2.97  1   36.65  ? 186 PRO B CG  1 
ATOM   9436  C  CD  . PRO F 2 205 ? 27.532  -74.734 -3.096 1   35.03  ? 186 PRO B CD  1 
ATOM   9437  N  N   . GLU F 2 206 ? 29.197  -78.164 -3.127 1   40.54  ? 187 GLU B N   1 
ATOM   9438  C  CA  . GLU F 2 206 ? 29.995  -79.356 -3.523 1   41.06  ? 187 GLU B CA  1 
ATOM   9439  C  C   . GLU F 2 206 ? 31.169  -79.541 -2.55  1   41.55  ? 187 GLU B C   1 
ATOM   9440  O  O   . GLU F 2 206 ? 31.438  -80.703 -2.169 1   44.63  ? 187 GLU B O   1 
ATOM   9441  C  CB  . GLU F 2 206 ? 30.446  -79.232 -4.978 1   40.61  ? 187 GLU B CB  1 
ATOM   9442  C  CG  . GLU F 2 206 ? 29.298  -79.267 -5.98  1   40.68  ? 187 GLU B CG  1 
ATOM   9443  C  CD  . GLU F 2 206 ? 28.694  -77.93  -6.384 1   42.31  ? 187 GLU B CD  1 
ATOM   9444  O  OE1 . GLU F 2 206 ? 28.98   -76.91  -5.719 1   41.66  ? 187 GLU B OE1 1 
ATOM   9445  O  OE2 . GLU F 2 206 ? 27.927  -77.91  -7.371 1   45.49  ? 187 GLU B OE2 1 
ATOM   9446  N  N   . GLN F 2 207 ? 31.822  -78.451 -2.137 1   40.16  ? 188 GLN B N   1 
ATOM   9447  C  CA  . GLN F 2 207 ? 32.901  -78.481 -1.112 1   40.16  ? 188 GLN B CA  1 
ATOM   9448  C  C   . GLN F 2 207 ? 32.332  -78.996 0.209  1   39.87  ? 188 GLN B C   1 
ATOM   9449  O  O   . GLN F 2 207 ? 32.912  -79.933 0.756  1   40.23  ? 188 GLN B O   1 
ATOM   9450  C  CB  . GLN F 2 207 ? 33.491  -77.097 -0.858 1   41.45  ? 188 GLN B CB  1 
ATOM   9451  C  CG  . GLN F 2 207 ? 34.524  -76.663 -1.88  1   42.51  ? 188 GLN B CG  1 
ATOM   9452  C  CD  . GLN F 2 207 ? 35.038  -75.294 -1.514 1   43.28  ? 188 GLN B CD  1 
ATOM   9453  O  OE1 . GLN F 2 207 ? 34.275  -74.334 -1.455 1   43.4   ? 188 GLN B OE1 1 
ATOM   9454  N  NE2 . GLN F 2 207 ? 36.328  -75.198 -1.228 1   44.13  ? 188 GLN B NE2 1 
ATOM   9455  N  N   . TRP F 2 208 ? 31.257  -78.367 0.697  1   41.2   ? 189 TRP B N   1 
ATOM   9456  C  CA  . TRP F 2 208 ? 30.55   -78.727 1.959  1   40.37  ? 189 TRP B CA  1 
ATOM   9457  C  C   . TRP F 2 208 ? 30.282  -80.24  1.993  1   43.06  ? 189 TRP B C   1 
ATOM   9458  O  O   . TRP F 2 208 ? 30.675  -80.879 2.987  1   44.19  ? 189 TRP B O   1 
ATOM   9459  C  CB  . TRP F 2 208 ? 29.26   -77.904 2.114  1   37.9   ? 189 TRP B CB  1 
ATOM   9460  C  CG  . TRP F 2 208 ? 28.352  -78.377 3.208  1   35.24  ? 189 TRP B CG  1 
ATOM   9461  C  CD1 . TRP F 2 208 ? 27.082  -78.854 3.067  1   34.97  ? 189 TRP B CD1 1 
ATOM   9462  C  CD2 . TRP F 2 208 ? 28.655  -78.45  4.612  1   33.29  ? 189 TRP B CD2 1 
ATOM   9463  N  NE1 . TRP F 2 208 ? 26.58   -79.232 4.283  1   35.26  ? 189 TRP B NE1 1 
ATOM   9464  C  CE2 . TRP F 2 208 ? 27.517  -78.989 5.251  1   34.17  ? 189 TRP B CE2 1 
ATOM   9465  C  CE3 . TRP F 2 208 ? 29.769  -78.112 5.392  1   33.33  ? 189 TRP B CE3 1 
ATOM   9466  C  CZ2 . TRP F 2 208 ? 27.458  -79.179 6.633  1   33.63  ? 189 TRP B CZ2 1 
ATOM   9467  C  CZ3 . TRP F 2 208 ? 29.72   -78.32  6.754  1   33.42  ? 189 TRP B CZ3 1 
ATOM   9468  C  CH2 . TRP F 2 208 ? 28.576  -78.845 7.365  1   33.81  ? 189 TRP B CH2 1 
ATOM   9469  N  N   . LYS F 2 209 ? 29.683  -80.786 0.929  1   47.9   ? 190 LYS B N   1 
ATOM   9470  C  CA  . LYS F 2 209 ? 29.219  -82.201 0.841  1   51.96  ? 190 LYS B CA  1 
ATOM   9471  C  C   . LYS F 2 209 ? 30.41   -83.171 0.865  1   51.97  ? 190 LYS B C   1 
ATOM   9472  O  O   . LYS F 2 209 ? 30.282  -84.237 1.504  1   55.78  ? 190 LYS B O   1 
ATOM   9473  C  CB  . LYS F 2 209 ? 28.389  -82.427 -0.427 1   54.77  ? 190 LYS B CB  1 
ATOM   9474  C  CG  . LYS F 2 209 ? 27.063  -81.675 -0.487 1   59.29  ? 190 LYS B CG  1 
ATOM   9475  C  CD  . LYS F 2 209 ? 25.872  -82.455 0.043  1   64.35  ? 190 LYS B CD  1 
ATOM   9476  C  CE  . LYS F 2 209 ? 24.549  -81.747 -0.181 1   67.51  ? 190 LYS B CE  1 
ATOM   9477  N  NZ  . LYS F 2 209 ? 23.388  -82.625 0.109  1   67.96  ? 190 LYS B NZ  1 
ATOM   9478  N  N   . SER F 2 210 ? 31.525  -82.82  0.216  1   49.39  ? 191 SER B N   1 
ATOM   9479  C  CA  . SER F 2 210 ? 32.648  -83.747 -0.094 1   49.18  ? 191 SER B CA  1 
ATOM   9480  C  C   . SER F 2 210 ? 33.77   -83.646 0.955  1   49.73  ? 191 SER B C   1 
ATOM   9481  O  O   . SER F 2 210 ? 34.944  -83.816 0.584  1   51.55  ? 191 SER B O   1 
ATOM   9482  C  CB  . SER F 2 210 ? 33.145  -83.5   -1.499 1   49.28  ? 191 SER B CB  1 
ATOM   9483  O  OG  . SER F 2 210 ? 33.636  -82.178 -1.645 1   48.4   ? 191 SER B OG  1 
ATOM   9484  N  N   . HIS F 2 211 ? 33.417  -83.426 2.226  1   50.53  ? 192 HIS B N   1 
ATOM   9485  C  CA  . HIS F 2 211 ? 34.344  -83.369 3.39   1   49.29  ? 192 HIS B CA  1 
ATOM   9486  C  C   . HIS F 2 211 ? 33.66   -84.012 4.604  1   48.44  ? 192 HIS B C   1 
ATOM   9487  O  O   . HIS F 2 211 ? 32.442  -83.809 4.758  1   45.99  ? 192 HIS B O   1 
ATOM   9488  C  CB  . HIS F 2 211 ? 34.774  -81.916 3.635  1   50.74  ? 192 HIS B CB  1 
ATOM   9489  C  CG  . HIS F 2 211 ? 35.908  -81.49  2.768  1   52.11  ? 192 HIS B CG  1 
ATOM   9490  N  ND1 . HIS F 2 211 ? 37.193  -81.9   3.027  1   55.19  ? 192 HIS B ND1 1 
ATOM   9491  C  CD2 . HIS F 2 211 ? 35.966  -80.729 1.65   1   51.48  ? 192 HIS B CD2 1 
ATOM   9492  C  CE1 . HIS F 2 211 ? 38.002  -81.411 2.116  1   55.93  ? 192 HIS B CE1 1 
ATOM   9493  N  NE2 . HIS F 2 211 ? 37.274  -80.68  1.25   1   52.96  ? 192 HIS B NE2 1 
ATOM   9494  N  N   . ARG F 2 212 ? 34.405  -84.778 5.411  1   49.76  ? 193 ARG B N   1 
ATOM   9495  C  CA  . ARG F 2 212 ? 33.853  -85.544 6.563  1   52.4   ? 193 ARG B CA  1 
ATOM   9496  C  C   . ARG F 2 212 ? 33.359  -84.556 7.629  1   52.01  ? 193 ARG B C   1 
ATOM   9497  O  O   . ARG F 2 212 ? 32.281  -84.82  8.209  1   52.56  ? 193 ARG B O   1 
ATOM   9498  C  CB  . ARG F 2 212 ? 34.877  -86.532 7.136  1   56.75  ? 193 ARG B CB  1 
ATOM   9499  C  CG  . ARG F 2 212 ? 35.035  -87.811 6.321  1   61.16  ? 193 ARG B CG  1 
ATOM   9500  C  CD  . ARG F 2 212 ? 36.167  -88.696 6.819  1   62.25  ? 193 ARG B CD  1 
ATOM   9501  N  NE  . ARG F 2 212 ? 36.455  -89.82  5.951  0   61.7   ? 193 ARG B NE  1 
ATOM   9502  C  CZ  . ARG F 2 212 ? 37.361  -90.771 6.178  0   61.75  ? 193 ARG B CZ  1 
ATOM   9503  N  NH1 . ARG F 2 212 ? 38.101  -90.767 7.277  0   61.74  ? 193 ARG B NH1 1 
ATOM   9504  N  NH2 . ARG F 2 212 ? 37.526  -91.737 5.293  0   61.71  ? 193 ARG B NH2 1 
ATOM   9505  N  N   . SER F 2 213 ? 34.103  -83.467 7.868  1   47.52  ? 194 SER B N   1 
ATOM   9506  C  CA  . SER F 2 213 ? 33.735  -82.405 8.841  1   47.19  ? 194 SER B CA  1 
ATOM   9507  C  C   . SER F 2 213 ? 34.449  -81.078 8.548  1   46.78  ? 194 SER B C   1 
ATOM   9508  O  O   . SER F 2 213 ? 35.458  -81.07  7.824  1   49.24  ? 194 SER B O   1 
ATOM   9509  C  CB  . SER F 2 213 ? 34.003  -82.855 10.256 1   46.74  ? 194 SER B CB  1 
ATOM   9510  O  OG  . SER F 2 213 ? 35.394  -82.923 10.523 1   45.69  ? 194 SER B OG  1 
ATOM   9511  N  N   . TYR F 2 214 ? 33.908  -79.994 9.103  1   44.73  ? 195 TYR B N   1 
ATOM   9512  C  CA  . TYR F 2 214 ? 34.525  -78.648 9.172  1   44.38  ? 195 TYR B CA  1 
ATOM   9513  C  C   . TYR F 2 214 ? 34.496  -78.18  10.629 1   44.36  ? 195 TYR B C   1 
ATOM   9514  O  O   . TYR F 2 214 ? 33.484  -78.43  11.308 1   45.43  ? 195 TYR B O   1 
ATOM   9515  C  CB  . TYR F 2 214 ? 33.769  -77.66  8.285  1   44.12  ? 195 TYR B CB  1 
ATOM   9516  C  CG  . TYR F 2 214 ? 33.993  -77.812 6.803  1   42.96  ? 195 TYR B CG  1 
ATOM   9517  C  CD1 . TYR F 2 214 ? 33.195  -78.647 6.038  1   43.04  ? 195 TYR B CD1 1 
ATOM   9518  C  CD2 . TYR F 2 214 ? 34.983  -77.09  6.158  1   43.92  ? 195 TYR B CD2 1 
ATOM   9519  C  CE1 . TYR F 2 214 ? 33.376  -78.769 4.67   1   43.13  ? 195 TYR B CE1 1 
ATOM   9520  C  CE2 . TYR F 2 214 ? 35.182  -77.203 4.792  1   44.83  ? 195 TYR B CE2 1 
ATOM   9521  C  CZ  . TYR F 2 214 ? 34.38   -78.05  4.046  1   44.16  ? 195 TYR B CZ  1 
ATOM   9522  O  OH  . TYR F 2 214 ? 34.576  -78.157 2.7    1   46.4   ? 195 TYR B OH  1 
ATOM   9523  N  N   . SER F 2 215 ? 35.558  -77.517 11.088 1   43.44  ? 196 SER B N   1 
ATOM   9524  C  CA  . SER F 2 215 ? 35.696  -77.027 12.483 1   44.18  ? 196 SER B CA  1 
ATOM   9525  C  C   . SER F 2 215 ? 35.963  -75.516 12.499 1   43.58  ? 196 SER B C   1 
ATOM   9526  O  O   . SER F 2 215 ? 36.647  -75.016 11.58  1   40.86  ? 196 SER B O   1 
ATOM   9527  C  CB  . SER F 2 215 ? 36.77   -77.788 13.215 1   45.37  ? 196 SER B CB  1 
ATOM   9528  O  OG  . SER F 2 215 ? 36.359  -79.118 13.48  1   48.25  ? 196 SER B OG  1 
ATOM   9529  N  N   . CYS F 2 216 ? 35.394  -74.83  13.496 1   43.33  ? 197 CYS B N   1 
ATOM   9530  C  CA  . CYS F 2 216 ? 35.743  -73.454 13.932 1   43.15  ? 197 CYS B CA  1 
ATOM   9531  C  C   . CYS F 2 216 ? 36.437  -73.56  15.294 1   43.83  ? 197 CYS B C   1 
ATOM   9532  O  O   . CYS F 2 216 ? 35.786  -74.049 16.234 1   44.64  ? 197 CYS B O   1 
ATOM   9533  C  CB  . CYS F 2 216 ? 34.505  -72.569 14.037 1   44.62  ? 197 CYS B CB  1 
ATOM   9534  S  SG  . CYS F 2 216 ? 34.857  -70.911 14.681 1   44.7   ? 197 CYS B SG  1 
ATOM   9535  N  N   . GLN F 2 217 ? 37.707  -73.142 15.372 1   44.12  ? 198 GLN B N   1 
ATOM   9536  C  CA  . GLN F 2 217 ? 38.556  -73.162 16.594 1   43.45  ? 198 GLN B CA  1 
ATOM   9537  C  C   . GLN F 2 217 ? 38.776  -71.722 17.067 1   41.2   ? 198 GLN B C   1 
ATOM   9538  O  O   . GLN F 2 217 ? 39.371  -70.932 16.304 1   42.88  ? 198 GLN B O   1 
ATOM   9539  C  CB  . GLN F 2 217 ? 39.895  -73.841 16.296 1   45.7   ? 198 GLN B CB  1 
ATOM   9540  C  CG  . GLN F 2 217 ? 39.759  -75.303 15.886 1   49.81  ? 198 GLN B CG  1 
ATOM   9541  C  CD  . GLN F 2 217 ? 41.074  -76.034 15.731 1   53.13  ? 198 GLN B CD  1 
ATOM   9542  O  OE1 . GLN F 2 217 ? 41.203  -77.195 16.115 1   52.73  ? 198 GLN B OE1 1 
ATOM   9543  N  NE2 . GLN F 2 217 ? 42.064  -75.379 15.144 1   55.98  ? 198 GLN B NE2 1 
ATOM   9544  N  N   . VAL F 2 218 ? 38.33   -71.398 18.28  1   39.6   ? 199 VAL B N   1 
ATOM   9545  C  CA  . VAL F 2 218 ? 38.436  -70.033 18.874 1   40.78  ? 199 VAL B CA  1 
ATOM   9546  C  C   . VAL F 2 218 ? 39.463  -70.087 20.005 1   41.64  ? 199 VAL B C   1 
ATOM   9547  O  O   . VAL F 2 218 ? 39.169  -70.732 21.02  1   43.4   ? 199 VAL B O   1 
ATOM   9548  C  CB  . VAL F 2 218 ? 37.074  -69.523 19.38  1   40.77  ? 199 VAL B CB  1 
ATOM   9549  C  CG1 . VAL F 2 218 ? 37.161  -68.095 19.904 1   40.58  ? 199 VAL B CG1 1 
ATOM   9550  C  CG2 . VAL F 2 218 ? 36.001  -69.633 18.308 1   42.05  ? 199 VAL B CG2 1 
ATOM   9551  N  N   . THR F 2 219 ? 40.614  -69.433 19.823 1   43.23  ? 200 THR B N   1 
ATOM   9552  C  CA  . THR F 2 219 ? 41.709  -69.325 20.825 1   42.66  ? 200 THR B CA  1 
ATOM   9553  C  C   . THR F 2 219 ? 41.566  -67.991 21.558 1   43.16  ? 200 THR B C   1 
ATOM   9554  O  O   . THR F 2 219 ? 41.565  -66.942 20.89  1   42.41  ? 200 THR B O   1 
ATOM   9555  C  CB  . THR F 2 219 ? 43.094  -69.441 20.178 1   42.22  ? 200 THR B CB  1 
ATOM   9556  O  OG1 . THR F 2 219 ? 43.086  -70.608 19.359 1   42.17  ? 200 THR B OG1 1 
ATOM   9557  C  CG2 . THR F 2 219 ? 44.22   -69.526 21.187 1   42.36  ? 200 THR B CG2 1 
ATOM   9558  N  N   . HIS F 2 220 ? 41.446  -68.05  22.882 1   42.96  ? 201 HIS B N   1 
ATOM   9559  C  CA  . HIS F 2 220 ? 41.281  -66.879 23.775 1   41.94  ? 201 HIS B CA  1 
ATOM   9560  C  C   . HIS F 2 220 ? 42.244  -67.032 24.954 1   44.18  ? 201 HIS B C   1 
ATOM   9561  O  O   . HIS F 2 220 ? 42.091  -68.015 25.709 1   48.09  ? 201 HIS B O   1 
ATOM   9562  C  CB  . HIS F 2 220 ? 39.817  -66.76  24.211 1   41.14  ? 201 HIS B CB  1 
ATOM   9563  C  CG  . HIS F 2 220 ? 39.574  -65.575 25.074 1   40.3   ? 201 HIS B CG  1 
ATOM   9564  N  ND1 . HIS F 2 220 ? 39.647  -65.654 26.442 1   40.24  ? 201 HIS B ND1 1 
ATOM   9565  C  CD2 . HIS F 2 220 ? 39.321  -64.285 24.77  1   38.82  ? 201 HIS B CD2 1 
ATOM   9566  C  CE1 . HIS F 2 220 ? 39.425  -64.465 26.952 1   41.31  ? 201 HIS B CE1 1 
ATOM   9567  N  NE2 . HIS F 2 220 ? 39.221  -63.604 25.945 1   39.95  ? 201 HIS B NE2 1 
ATOM   9568  N  N   . GLU F 2 221 ? 43.21   -66.118 25.076 1   45.21  ? 202 GLU B N   1 
ATOM   9569  C  CA  . GLU F 2 221 ? 44.234  -66.1   26.154 1   45.62  ? 202 GLU B CA  1 
ATOM   9570  C  C   . GLU F 2 221 ? 44.815  -67.513 26.325 1   45.85  ? 202 GLU B C   1 
ATOM   9571  O  O   . GLU F 2 221 ? 44.885  -67.987 27.469 1   48.68  ? 202 GLU B O   1 
ATOM   9572  C  CB  . GLU F 2 221 ? 43.613  -65.555 27.446 1   47.28  ? 202 GLU B CB  1 
ATOM   9573  C  CG  . GLU F 2 221 ? 42.991  -64.17  27.31  1   48.07  ? 202 GLU B CG  1 
ATOM   9574  C  CD  . GLU F 2 221 ? 43.957  -63.031 27.01  1   49.36  ? 202 GLU B CD  1 
ATOM   9575  O  OE1 . GLU F 2 221 ? 44.907  -62.835 27.795 1   50.6   ? 202 GLU B OE1 1 
ATOM   9576  O  OE2 . GLU F 2 221 ? 43.754  -62.334 25.991 1   51.62  ? 202 GLU B OE2 1 
ATOM   9577  N  N   . GLY F 2 222 ? 45.178  -68.17  25.217 1   45.17  ? 203 GLY B N   1 
ATOM   9578  C  CA  . GLY F 2 222 ? 45.929  -69.441 25.201 1   45.58  ? 203 GLY B CA  1 
ATOM   9579  C  C   . GLY F 2 222 ? 45.076  -70.68  25.429 1   46.81  ? 203 GLY B C   1 
ATOM   9580  O  O   . GLY F 2 222 ? 45.672  -71.756 25.614 1   54.06  ? 203 GLY B O   1 
ATOM   9581  N  N   . SER F 2 223 ? 43.746  -70.561 25.426 1   47.92  ? 204 SER B N   1 
ATOM   9582  C  CA  . SER F 2 223 ? 42.785  -71.69  25.554 1   48.49  ? 204 SER B CA  1 
ATOM   9583  C  C   . SER F 2 223 ? 41.856  -71.691 24.34  1   47.65  ? 204 SER B C   1 
ATOM   9584  O  O   . SER F 2 223 ? 41.246  -70.636 24.063 1   49.85  ? 204 SER B O   1 
ATOM   9585  C  CB  . SER F 2 223 ? 41.999  -71.618 26.833 1   50     ? 204 SER B CB  1 
ATOM   9586  O  OG  . SER F 2 223 ? 42.834  -71.897 27.946 1   55.17  ? 204 SER B OG  1 
ATOM   9587  N  N   . THR F 2 224 ? 41.765  -72.828 23.648 1   46.62  ? 205 THR B N   1 
ATOM   9588  C  CA  . THR F 2 224 ? 40.99   -72.99  22.392 1   45.64  ? 205 THR B CA  1 
ATOM   9589  C  C   . THR F 2 224 ? 39.654  -73.671 22.701 1   46.51  ? 205 THR B C   1 
ATOM   9590  O  O   . THR F 2 224 ? 39.64   -74.603 23.529 1   46.69  ? 205 THR B O   1 
ATOM   9591  C  CB  . THR F 2 224 ? 41.79   -73.764 21.34  1   43.61  ? 205 THR B CB  1 
ATOM   9592  O  OG1 . THR F 2 224 ? 43.115  -73.242 21.341 1   42.19  ? 205 THR B OG1 1 
ATOM   9593  C  CG2 . THR F 2 224 ? 41.203  -73.645 19.951 1   43.32  ? 205 THR B CG2 1 
ATOM   9594  N  N   . VAL F 2 225 ? 38.584  -73.2   22.057 1   47.23  ? 206 VAL B N   1 
ATOM   9595  C  CA  . VAL F 2 225 ? 37.229  -73.822 22.051 1   48.06  ? 206 VAL B CA  1 
ATOM   9596  C  C   . VAL F 2 225 ? 36.965  -74.282 20.616 1   49.31  ? 206 VAL B C   1 
ATOM   9597  O  O   . VAL F 2 225 ? 37.035  -73.431 19.713 1   51.94  ? 206 VAL B O   1 
ATOM   9598  C  CB  . VAL F 2 225 ? 36.156  -72.83  22.538 1   48.7   ? 206 VAL B CB  1 
ATOM   9599  C  CG1 . VAL F 2 225 ? 34.779  -73.472 22.614 1   48.66  ? 206 VAL B CG1 1 
ATOM   9600  C  CG2 . VAL F 2 225 ? 36.523  -72.204 23.876 1   48.41  ? 206 VAL B CG2 1 
ATOM   9601  N  N   . GLU F 2 226 ? 36.716  -75.577 20.413 1   50.88  ? 207 GLU B N   1 
ATOM   9602  C  CA  . GLU F 2 226 ? 36.46   -76.176 19.076 1   51.47  ? 207 GLU B CA  1 
ATOM   9603  C  C   . GLU F 2 226 ? 34.984  -76.574 18.98  1   48.93  ? 207 GLU B C   1 
ATOM   9604  O  O   . GLU F 2 226 ? 34.499  -77.272 19.891 1   50.46  ? 207 GLU B O   1 
ATOM   9605  C  CB  . GLU F 2 226 ? 37.358  -77.39  18.835 1   54.47  ? 207 GLU B CB  1 
ATOM   9606  C  CG  . GLU F 2 226 ? 37.218  -77.961 17.433 1   58.77  ? 207 GLU B CG  1 
ATOM   9607  C  CD  . GLU F 2 226 ? 38.119  -79.139 17.119 1   61.78  ? 207 GLU B CD  1 
ATOM   9608  O  OE1 . GLU F 2 226 ? 38.121  -80.1   17.916 1   67.52  ? 207 GLU B OE1 1 
ATOM   9609  O  OE2 . GLU F 2 226 ? 38.803  -79.097 16.073 1   62.83  ? 207 GLU B OE2 1 
ATOM   9610  N  N   . LYS F 2 227 ? 34.311  -76.134 17.916 1   46.15  ? 208 LYS B N   1 
ATOM   9611  C  CA  . LYS F 2 227 ? 32.986  -76.64  17.475 1   47.34  ? 208 LYS B CA  1 
ATOM   9612  C  C   . LYS F 2 227 ? 33.144  -77.236 16.073 1   45.64  ? 208 LYS B C   1 
ATOM   9613  O  O   . LYS F 2 227 ? 33.889  -76.652 15.257 1   42.98  ? 208 LYS B O   1 
ATOM   9614  C  CB  . LYS F 2 227 ? 31.94   -75.524 17.515 1   48.42  ? 208 LYS B CB  1 
ATOM   9615  C  CG  . LYS F 2 227 ? 31.608  -75.021 18.912 1   51.15  ? 208 LYS B CG  1 
ATOM   9616  C  CD  . LYS F 2 227 ? 30.718  -75.959 19.696 1   53.27  ? 208 LYS B CD  1 
ATOM   9617  C  CE  . LYS F 2 227 ? 30.721  -75.678 21.184 1   55.45  ? 208 LYS B CE  1 
ATOM   9618  N  NZ  . LYS F 2 227 ? 29.352  -75.754 21.751 1   58.35  ? 208 LYS B NZ  1 
ATOM   9619  N  N   . THR F 2 228 ? 32.497  -78.378 15.828 1   43.69  ? 209 THR B N   1 
ATOM   9620  C  CA  . THR F 2 228 ? 32.6    -79.157 14.569 1   43.04  ? 209 THR B CA  1 
ATOM   9621  C  C   . THR F 2 228 ? 31.194  -79.42  14.031 1   41.54  ? 209 THR B C   1 
ATOM   9622  O  O   . THR F 2 228 ? 30.311  -79.749 14.83  1   44.38  ? 209 THR B O   1 
ATOM   9623  C  CB  . THR F 2 228 ? 33.383  -80.459 14.78  1   43.44  ? 209 THR B CB  1 
ATOM   9624  O  OG1 . THR F 2 228 ? 34.673  -80.135 15.303 1   41.32  ? 209 THR B OG1 1 
ATOM   9625  C  CG2 . THR F 2 228 ? 33.544  -81.261 13.506 1   43.78  ? 209 THR B CG2 1 
ATOM   9626  N  N   . VAL F 2 229 ? 31.027  -79.286 12.718 1   42.5   ? 210 VAL B N   1 
ATOM   9627  C  CA  . VAL F 2 229 ? 29.803  -79.674 11.961 1   44.24  ? 210 VAL B CA  1 
ATOM   9628  C  C   . VAL F 2 229 ? 30.221  -80.606 10.82  1   47.55  ? 210 VAL B C   1 
ATOM   9629  O  O   . VAL F 2 229 ? 31.358  -80.474 10.32  1   50.41  ? 210 VAL B O   1 
ATOM   9630  C  CB  . VAL F 2 229 ? 29.034  -78.448 11.437 1   45.22  ? 210 VAL B CB  1 
ATOM   9631  C  CG1 . VAL F 2 229 ? 28.334  -77.716 12.567 1   46.01  ? 210 VAL B CG1 1 
ATOM   9632  C  CG2 . VAL F 2 229 ? 29.914  -77.49  10.642 1   45.33  ? 210 VAL B CG2 1 
ATOM   9633  N  N   . ALA F 2 230 ? 29.329  -81.522 10.444 1   52.05  ? 211 ALA B N   1 
ATOM   9634  C  CA  . ALA F 2 230 ? 29.493  -82.474 9.321  1   51.98  ? 211 ALA B CA  1 
ATOM   9635  C  C   . ALA F 2 230 ? 28.243  -82.407 8.45   1   51.86  ? 211 ALA B C   1 
ATOM   9636  O  O   . ALA F 2 230 ? 27.154  -82.191 8.975  1   58.26  ? 211 ALA B O   1 
ATOM   9637  C  CB  . ALA F 2 230 ? 29.724  -83.862 9.867  1   52.44  ? 211 ALA B CB  1 
ATOM   9638  N  N   . PRO F 2 231 ? 28.335  -82.559 7.109  1   52.21  ? 212 PRO B N   1 
ATOM   9639  C  CA  . PRO F 2 231 ? 27.132  -82.637 6.273  1   55.06  ? 212 PRO B CA  1 
ATOM   9640  C  C   . PRO F 2 231 ? 26.235  -83.856 6.57   1   58.06  ? 212 PRO B C   1 
ATOM   9641  O  O   . PRO F 2 231 ? 25.049  -83.761 6.304  1   55.17  ? 212 PRO B O   1 
ATOM   9642  C  CB  . PRO F 2 231 ? 27.692  -82.676 4.84   1   54.35  ? 212 PRO B CB  1 
ATOM   9643  C  CG  . PRO F 2 231 ? 29.102  -83.197 4.997  1   53     ? 212 PRO B CG  1 
ATOM   9644  C  CD  . PRO F 2 231 ? 29.576  -82.641 6.322  1   51.59  ? 212 PRO B CD  1 
ATOM   9645  N  N   . THR F 2 232 ? 26.801  -84.935 7.134  1   65.9   ? 213 THR B N   1 
ATOM   9646  C  CA  . THR F 2 232 ? 26.114  -86.222 7.448  1   75.11  ? 213 THR B CA  1 
ATOM   9647  C  C   . THR F 2 232 ? 25.858  -86.35  8.961  1   81.14  ? 213 THR B C   1 
ATOM   9648  O  O   . THR F 2 232 ? 26.151  -87.432 9.517  1   81.27  ? 213 THR B O   1 
ATOM   9649  C  CB  . THR F 2 232 ? 26.935  -87.408 6.914  1   75.49  ? 213 THR B CB  1 
ATOM   9650  O  OG1 . THR F 2 232 ? 28.234  -87.342 7.506  1   74.88  ? 213 THR B OG1 1 
ATOM   9651  C  CG2 . THR F 2 232 ? 27.057  -87.418 5.406  1   75.03  ? 213 THR B CG2 1 
ATOM   9652  N  N   . GLU F 2 233 ? 25.323  -85.305 9.607  1   87.28  ? 214 GLU B N   1 
ATOM   9653  C  CA  . GLU F 2 233 ? 24.893  -85.346 11.036 1   92.81  ? 214 GLU B CA  1 
ATOM   9654  C  C   . GLU F 2 233 ? 23.917  -84.198 11.333 1   98.41  ? 214 GLU B C   1 
ATOM   9655  O  O   . GLU F 2 233 ? 23.673  -83.373 10.426 1   96.52  ? 214 GLU B O   1 
ATOM   9656  C  CB  . GLU F 2 233 ? 26.102  -85.308 11.982 1   96.54  ? 214 GLU B CB  1 
ATOM   9657  C  CG  . GLU F 2 233 ? 26.679  -83.916 12.228 1   99.87  ? 214 GLU B CG  1 
ATOM   9658  C  CD  . GLU F 2 233 ? 27.894  -83.861 13.14  1   101.04 ? 214 GLU B CD  1 
ATOM   9659  O  OE1 . GLU F 2 233 ? 28.222  -84.892 13.766 1   100.96 ? 214 GLU B OE1 1 
ATOM   9660  O  OE2 . GLU F 2 233 ? 28.506  -82.777 13.23  1   101.08 ? 214 GLU B OE2 1 
ATOM   9661  N  N   . CYS F 2 234 ? 23.401  -84.157 12.57  1   104.38 ? 215 CYS B N   1 
ATOM   9662  C  CA  . CYS F 2 234 ? 22.519  -83.091 13.124 1   107.02 ? 215 CYS B CA  1 
ATOM   9663  C  C   . CYS F 2 234 ? 23.232  -82.39  14.291 1   105.65 ? 215 CYS B C   1 
ATOM   9664  O  O   . CYS F 2 234 ? 22.633  -81.757 15.168 1   103.34 ? 215 CYS B O   1 
ATOM   9665  C  CB  . CYS F 2 234 ? 21.185  -83.666 13.589 1   107.41 ? 215 CYS B CB  1 
ATOM   9666  S  SG  . CYS F 2 234 ? 20.458  -84.87  12.447 1   111.55 ? 215 CYS B SG  1 
HETATM 9667  C  C1  . EDO G 4 .   ? 18.554  46.364  44.207 1   71.38  ? 301 EDO H C1  1 
HETATM 9668  O  O1  . EDO G 4 .   ? 19.29   46.359  42.999 1   69.3   ? 301 EDO H O1  1 
HETATM 9669  C  C2  . EDO G 4 .   ? 17.088  46.484  43.986 1   73.99  ? 301 EDO H C2  1 
HETATM 9670  O  O2  . EDO G 4 .   ? 16.387  45.268  43.743 1   74.06  ? 301 EDO H O2  1 
HETATM 9671  C  C1  . EDO H 4 .   ? 22.304  23.648  49.206 1   79.51  ? 302 EDO H C1  1 
HETATM 9672  O  O1  . EDO H 4 .   ? 23.345  24.085  48.35  1   76.84  ? 302 EDO H O1  1 
HETATM 9673  C  C2  . EDO H 4 .   ? 21.406  22.635  48.574 1   80.48  ? 302 EDO H C2  1 
HETATM 9674  O  O2  . EDO H 4 .   ? 20.013  22.81   48.811 1   81.2   ? 302 EDO H O2  1 
HETATM 9675  C  C1  . PEG I 5 .   ? 5.354   62.735  38.94  1   68.25  ? 303 PEG H C1  1 
HETATM 9676  O  O1  . PEG I 5 .   ? 6.653   62.261  38.648 1   61.61  ? 303 PEG H O1  1 
HETATM 9677  C  C2  . PEG I 5 .   ? 4.98    62.541  40.379 1   70.71  ? 303 PEG H C2  1 
HETATM 9678  O  O2  . PEG I 5 .   ? 3.563   62.615  40.521 1   76.27  ? 303 PEG H O2  1 
HETATM 9679  C  C3  . PEG I 5 .   ? 2.933   61.339  40.618 1   79.97  ? 303 PEG H C3  1 
HETATM 9680  C  C4  . PEG I 5 .   ? 1.437   61.497  40.606 1   79.62  ? 303 PEG H C4  1 
HETATM 9681  O  O4  . PEG I 5 .   ? 0.744   60.285  40.877 1   78.43  ? 303 PEG H O4  1 
HETATM 9682  C  C1  . PEG J 5 .   ? 44.698  53.281  13.452 1   69.26  ? 301 PEG L C1  1 
HETATM 9683  O  O1  . PEG J 5 .   ? 45.492  54.308  14.008 1   64.52  ? 301 PEG L O1  1 
HETATM 9684  C  C2  . PEG J 5 .   ? 43.77   53.785  12.39  1   71.89  ? 301 PEG L C2  1 
HETATM 9685  O  O2  . PEG J 5 .   ? 42.419  53.642  12.821 1   76.2   ? 301 PEG L O2  1 
HETATM 9686  C  C3  . PEG J 5 .   ? 41.463  54.043  11.842 1   78.86  ? 301 PEG L C3  1 
HETATM 9687  C  C4  . PEG J 5 .   ? 40.454  54.97   12.458 1   79.05  ? 301 PEG L C4  1 
HETATM 9688  O  O4  . PEG J 5 .   ? 39.408  55.325  11.566 1   80.12  ? 301 PEG L O4  1 
HETATM 9689  MG MG  . MG  K 6 .   ? 39.11   79.995  51.886 1   35.43  2 302 MG  L MG  1 
HETATM 9690  MG MG  . MG  L 6 .   ? -0.324  20.215  52.758 0.5 71.48  2 501 MG  P MG  1 
HETATM 9691  C  C1  . PEG M 5 .   ? 23.478  -77.174 15.279 1   84.71  ? 301 PEG A C1  1 
HETATM 9692  O  O1  . PEG M 5 .   ? 24.607  -76.332 15.453 1   81.64  ? 301 PEG A O1  1 
HETATM 9693  C  C2  . PEG M 5 .   ? 23.06   -77.296 13.84  1   83.77  ? 301 PEG A C2  1 
HETATM 9694  O  O2  . PEG M 5 .   ? 22.453  -76.081 13.402 1   81.34  ? 301 PEG A O2  1 
HETATM 9695  C  C3  . PEG M 5 .   ? 21.913  -76.139 12.082 1   80.16  ? 301 PEG A C3  1 
HETATM 9696  C  C4  . PEG M 5 .   ? 21.965  -74.77  11.442 1   80.69  ? 301 PEG A C4  1 
HETATM 9697  O  O4  . PEG M 5 .   ? 21.608  -74.769 10.071 1   81.38  ? 301 PEG A O4  1 
HETATM 9698  C  C1  . EDO N 4 .   ? 22.781  -23.322 4.655  1   69.61  ? 302 EDO A C1  1 
HETATM 9699  O  O1  . EDO N 4 .   ? 23.16   -24.309 3.712  1   67.46  ? 302 EDO A O1  1 
HETATM 9700  C  C2  . EDO N 4 .   ? 21.648  -22.478 4.191  1   71.1   ? 302 EDO A C2  1 
HETATM 9701  O  O2  . EDO N 4 .   ? 20.515  -23.215 3.752  1   72.88  ? 302 EDO A O2  1 
HETATM 9702  C  C1  . PEG O 5 .   ? 20.975  -47.344 12.637 1   84.19  ? 303 PEG A C1  1 
HETATM 9703  O  O1  . PEG O 5 .   ? 22.39   -47.419 12.665 1   77.63  ? 303 PEG A O1  1 
HETATM 9704  C  C2  . PEG O 5 .   ? 20.479  -46.416 11.568 1   85.05  ? 303 PEG A C2  1 
HETATM 9705  O  O2  . PEG O 5 .   ? 19.242  -46.886 11.029 1   87.37  ? 303 PEG A O2  1 
HETATM 9706  C  C3  . PEG O 5 .   ? 18.986  -46.457 9.692  1   82.57  ? 303 PEG A C3  1 
HETATM 9707  C  C4  . PEG O 5 .   ? 17.911  -47.282 9.066  1   83.2   ? 303 PEG A C4  1 
HETATM 9708  O  O4  . PEG O 5 .   ? 17.749  -46.996 7.683  1   83.9   ? 303 PEG A O4  1 
HETATM 9709  C  C1  . PEG P 5 .   ? 28.638  -44.368 14.932 1   85.96  ? 304 PEG A C1  1 
HETATM 9710  O  O1  . PEG P 5 .   ? 28.005  -44.504 13.676 1   79.99  ? 304 PEG A O1  1 
HETATM 9711  C  C2  . PEG P 5 .   ? 28.928  -45.692 15.574 1   86.6   ? 304 PEG A C2  1 
HETATM 9712  O  O2  . PEG P 5 .   ? 29.649  -45.489 16.787 1   87.21  ? 304 PEG A O2  1 
HETATM 9713  C  C3  . PEG P 5 .   ? 29.609  -46.601 17.678 1   84.37  ? 304 PEG A C3  1 
HETATM 9714  C  C4  . PEG P 5 .   ? 28.443  -46.469 18.625 1   81.85  ? 304 PEG A C4  1 
HETATM 9715  O  O4  . PEG P 5 .   ? 28.796  -46.687 19.985 1   80.52  ? 304 PEG A O4  1 
HETATM 9716  C  C1  . EDO Q 4 .   ? 27.036  -53.428 13.417 1   84.11  ? 305 EDO A C1  1 
HETATM 9717  O  O1  . EDO Q 4 .   ? 27.416  -52.068 13.484 1   81.27  ? 305 EDO A O1  1 
HETATM 9718  C  C2  . EDO Q 4 .   ? 25.883  -53.679 12.502 1   86.56  ? 305 EDO A C2  1 
HETATM 9719  O  O2  . EDO Q 4 .   ? 25.024  -54.761 12.844 1   87.02  ? 305 EDO A O2  1 
HETATM 9720  MG MG  . MG  R 6 .   ? 38.646  -79.529 0      0.5 33.79  2 301 MG  B MG  1 
HETATM 9721  O  O   . HOH S 7 .   ? 15.562  45.572  47.873 1   52.31  ? 401 HOH H O   1 
HETATM 9722  O  O   . HOH S 7 .   ? 19.303  74      43.505 1   37.12  ? 402 HOH H O   1 
HETATM 9723  O  O   . HOH S 7 .   ? 22.492  82.206  35.458 1   63.27  ? 403 HOH H O   1 
HETATM 9724  O  O   . HOH S 7 .   ? 12.801  37.812  48.034 1   43.23  ? 404 HOH H O   1 
HETATM 9725  O  O   . HOH S 7 .   ? 21.652  75.802  40.382 1   35.86  ? 405 HOH H O   1 
HETATM 9726  O  O   . HOH S 7 .   ? 12.292  86.153  44.858 1   55.62  ? 406 HOH H O   1 
HETATM 9727  O  O   . HOH S 7 .   ? 31.623  38.245  39.741 1   39.26  ? 407 HOH H O   1 
HETATM 9728  O  O   . HOH S 7 .   ? 21.693  61.483  54.063 1   42.61  ? 408 HOH H O   1 
HETATM 9729  O  O   . HOH S 7 .   ? 13.548  33.872  25.307 1   43.39  ? 409 HOH H O   1 
HETATM 9730  O  O   . HOH S 7 .   ? 22      75.214  34.662 1   51.2   ? 410 HOH H O   1 
HETATM 9731  O  O   . HOH S 7 .   ? 31.973  43.733  34.853 1   39.4   ? 411 HOH H O   1 
HETATM 9732  O  O   . HOH S 7 .   ? 12.872  73.883  36.443 1   43.48  ? 412 HOH H O   1 
HETATM 9733  O  O   . HOH S 7 .   ? 16.487  13.971  39.464 1   53.75  ? 413 HOH H O   1 
HETATM 9734  O  O   . HOH S 7 .   ? 15.034  25.618  28.991 1   34.74  ? 414 HOH H O   1 
HETATM 9735  O  O   . HOH S 7 .   ? 32.123  44.803  55.909 1   59.41  ? 415 HOH H O   1 
HETATM 9736  O  O   . HOH S 7 .   ? 24.221  55.644  35.637 1   58.96  ? 416 HOH H O   1 
HETATM 9737  O  O   . HOH S 7 .   ? 30.151  27.908  49.864 1   59.26  ? 417 HOH H O   1 
HETATM 9738  O  O   . HOH S 7 .   ? 17.06   42.341  30.417 1   41.92  ? 418 HOH H O   1 
HETATM 9739  O  O   . HOH S 7 .   ? 20.919  46.181  37.88  1   49.85  ? 419 HOH H O   1 
HETATM 9740  O  O   . HOH S 7 .   ? 13.815  73.427  42.917 1   45.49  ? 420 HOH H O   1 
HETATM 9741  O  O   . HOH S 7 .   ? 21.127  78.191  29.711 1   60     ? 421 HOH H O   1 
HETATM 9742  O  O   . HOH S 7 .   ? 14.381  65.854  50.595 1   48.63  ? 422 HOH H O   1 
HETATM 9743  O  O   . HOH S 7 .   ? 8.513   62.357  48.1   1   43.89  ? 423 HOH H O   1 
HETATM 9744  O  O   . HOH S 7 .   ? 13.514  40.704  30.479 1   44.44  ? 424 HOH H O   1 
HETATM 9745  O  O   . HOH S 7 .   ? 11.902  37.682  51.712 1   48.27  ? 425 HOH H O   1 
HETATM 9746  O  O   . HOH S 7 .   ? 10.945  24.302  43.721 1   44.58  ? 426 HOH H O   1 
HETATM 9747  O  O   . HOH S 7 .   ? 12.948  55.599  40.587 1   49.93  ? 427 HOH H O   1 
HETATM 9748  O  O   . HOH S 7 .   ? 18.887  55.439  37.412 1   39.27  ? 428 HOH H O   1 
HETATM 9749  O  O   . HOH S 7 .   ? 28.214  44.216  38.667 1   42.36  ? 429 HOH H O   1 
HETATM 9750  O  O   . HOH S 7 .   ? 20.005  51.583  59.746 1   55.57  ? 430 HOH H O   1 
HETATM 9751  O  O   . HOH S 7 .   ? 22.9    54.613  58.813 1   50.69  ? 431 HOH H O   1 
HETATM 9752  O  O   . HOH S 7 .   ? 2.299   35.626  32.155 1   48.12  ? 432 HOH H O   1 
HETATM 9753  O  O   . HOH S 7 .   ? 9.588   26.461  24.179 1   51.05  ? 433 HOH H O   1 
HETATM 9754  O  O   . HOH S 7 .   ? 16.573  39.702  27.882 1   40.21  ? 434 HOH H O   1 
HETATM 9755  O  O   . HOH S 7 .   ? 14.89   88.937  38.576 1   57.73  ? 435 HOH H O   1 
HETATM 9756  O  O   . HOH S 7 .   ? 32.773  56.098  40.372 1   45.85  ? 436 HOH H O   1 
HETATM 9757  O  O   . HOH S 7 .   ? 27.228  48.899  47.654 1   39.23  ? 437 HOH H O   1 
HETATM 9758  O  O   . HOH S 7 .   ? 10.601  46.034  44.581 1   40.88  ? 438 HOH H O   1 
HETATM 9759  O  O   . HOH S 7 .   ? 6.499   32.166  48.318 1   46.32  ? 439 HOH H O   1 
HETATM 9760  O  O   . HOH S 7 .   ? 7.195   64.944  30.705 1   44.67  ? 440 HOH H O   1 
HETATM 9761  O  O   . HOH S 7 .   ? 21.921  57.751  32.083 1   49.77  ? 441 HOH H O   1 
HETATM 9762  O  O   . HOH S 7 .   ? 27.045  53.731  40.031 1   55.15  ? 442 HOH H O   1 
HETATM 9763  O  O   . HOH S 7 .   ? 27.2    57.417  32.16  1   55.44  ? 443 HOH H O   1 
HETATM 9764  O  O   . HOH S 7 .   ? 5.108   29.271  28.33  1   45.66  ? 444 HOH H O   1 
HETATM 9765  O  O   . HOH S 7 .   ? 29.296  52.905  55.003 1   47.49  ? 445 HOH H O   1 
HETATM 9766  O  O   . HOH S 7 .   ? 16.896  32.2    56.791 1   59.28  ? 446 HOH H O   1 
HETATM 9767  O  O   . HOH S 7 .   ? 11.302  61.986  26.231 1   43.24  ? 447 HOH H O   1 
HETATM 9768  O  O   . HOH S 7 .   ? 15.498  85.864  45.594 1   59.14  ? 448 HOH H O   1 
HETATM 9769  O  O   . HOH S 7 .   ? 15.279  63.551  51.197 1   52.75  ? 449 HOH H O   1 
HETATM 9770  O  O   . HOH S 7 .   ? 21.425  48.097  58.588 1   54.29  ? 450 HOH H O   1 
HETATM 9771  O  O   . HOH S 7 .   ? 27.578  65.827  54.179 1   63.49  ? 451 HOH H O   1 
HETATM 9772  O  O   . HOH S 7 .   ? 28.874  24.995  52.726 1   53.6   ? 452 HOH H O   1 
HETATM 9773  O  O   . HOH S 7 .   ? 5.549   74.745  36.656 1   69.92  ? 453 HOH H O   1 
HETATM 9774  O  O   . HOH S 7 .   ? 35.677  41.937  33.542 1   44.95  ? 454 HOH H O   1 
HETATM 9775  O  O   . HOH S 7 .   ? 6.849   78.686  26.937 1   43.7   ? 455 HOH H O   1 
HETATM 9776  O  O   . HOH S 7 .   ? 29.689  45.701  37.074 1   43.76  ? 456 HOH H O   1 
HETATM 9777  O  O   . HOH S 7 .   ? 12.225  75.406  22.473 1   50.16  ? 457 HOH H O   1 
HETATM 9778  O  O   . HOH S 7 .   ? 16.916  50.894  43.932 1   65.07  ? 458 HOH H O   1 
HETATM 9779  O  O   . HOH S 7 .   ? 3.754   40.23   29.373 1   54.97  ? 459 HOH H O   1 
HETATM 9780  O  O   . HOH S 7 .   ? 34.061  56.518  42.908 1   42.47  ? 460 HOH H O   1 
HETATM 9781  O  O   . HOH S 7 .   ? 14.314  81.097  31.728 1   42.96  ? 461 HOH H O   1 
HETATM 9782  O  O   . HOH S 7 .   ? 12.244  80.989  34.228 1   61.34  ? 462 HOH H O   1 
HETATM 9783  O  O   . HOH S 7 .   ? 23.13   76.948  38.248 1   59.9   ? 463 HOH H O   1 
HETATM 9784  O  O   . HOH S 7 .   ? 2.469   35.784  34.892 1   49.06  ? 464 HOH H O   1 
HETATM 9785  O  O   . HOH S 7 .   ? 21.84   47.187  40.361 1   55.47  ? 465 HOH H O   1 
HETATM 9786  O  O   . HOH S 7 .   ? 21.756  55.18   34.266 1   55.53  ? 466 HOH H O   1 
HETATM 9787  O  O   . HOH S 7 .   ? 33.537  32.685  37.423 1   57.17  ? 467 HOH H O   1 
HETATM 9788  O  O   . HOH S 7 .   ? 19.899  77.747  44.398 1   72.53  ? 468 HOH H O   1 
HETATM 9789  O  O   . HOH S 7 .   ? 1.944   32.732  31.342 1   51.53  ? 469 HOH H O   1 
HETATM 9790  O  O   . HOH S 7 .   ? 30.962  50.978  54.227 1   50.9   ? 470 HOH H O   1 
HETATM 9791  O  O   . HOH S 7 .   ? 5.328   81.663  34.924 1   47.32  ? 471 HOH H O   1 
HETATM 9792  O  O   . HOH S 7 .   ? 19.263  49.141  39.612 1   56.04  ? 472 HOH H O   1 
HETATM 9793  O  O   . HOH S 7 .   ? 18.732  86.77   46.07  1   64.23  ? 473 HOH H O   1 
HETATM 9794  O  O   . HOH T 7 .   ? 33.221  35.552  33.779 1   43.34  ? 401 HOH L O   1 
HETATM 9795  O  O   . HOH T 7 .   ? 39.807  65.258  41.642 1   35.06  ? 402 HOH L O   1 
HETATM 9796  O  O   . HOH T 7 .   ? 30.81   53.838  14.016 1   50.54  ? 403 HOH L O   1 
HETATM 9797  O  O   . HOH T 7 .   ? 27.838  61.257  40.403 1   26.28  ? 404 HOH L O   1 
HETATM 9798  O  O   . HOH T 7 .   ? 41.017  34.705  18.299 1   44.04  ? 405 HOH L O   1 
HETATM 9799  O  O   . HOH T 7 .   ? 37.772  53.109  23.72  1   46.82  ? 406 HOH L O   1 
HETATM 9800  O  O   . HOH T 7 .   ? 43.043  63.808  29.368 1   49.63  ? 407 HOH L O   1 
HETATM 9801  O  O   . HOH T 7 .   ? 34.676  32.172  14.831 1   41.94  ? 408 HOH L O   1 
HETATM 9802  O  O   . HOH T 7 .   ? 32.748  66.081  48.521 1   37.6   ? 409 HOH L O   1 
HETATM 9803  O  O   . HOH T 7 .   ? 36.287  71.918  50.754 1   29.06  ? 410 HOH L O   1 
HETATM 9804  O  O   . HOH T 7 .   ? 20.548  19.872  21.366 1   38.51  ? 411 HOH L O   1 
HETATM 9805  O  O   . HOH T 7 .   ? 39.819  54.638  19.961 1   40.13  ? 412 HOH L O   1 
HETATM 9806  O  O   . HOH T 7 .   ? 42.246  71.097  35.874 1   34.14  ? 413 HOH L O   1 
HETATM 9807  O  O   . HOH T 7 .   ? 39.898  51.643  9.793  1   46.06  ? 414 HOH L O   1 
HETATM 9808  O  O   . HOH T 7 .   ? 33.436  32.381  12.625 1   35.78  ? 415 HOH L O   1 
HETATM 9809  O  O   . HOH T 7 .   ? 16.206  71.608  54.094 1   39.07  ? 416 HOH L O   1 
HETATM 9810  O  O   . HOH T 7 .   ? 31.699  37.065  11.335 1   40.66  ? 417 HOH L O   1 
HETATM 9811  O  O   . HOH T 7 .   ? 26.622  34.068  11.983 1   52.74  ? 418 HOH L O   1 
HETATM 9812  O  O   . HOH T 7 .   ? 43.049  54.905  18.911 1   47.42  ? 419 HOH L O   1 
HETATM 9813  O  O   . HOH T 7 .   ? 24.684  27.875  11.686 1   52.48  ? 420 HOH L O   1 
HETATM 9814  O  O   . HOH T 7 .   ? 31.761  30.499  35.167 1   57.86  ? 421 HOH L O   1 
HETATM 9815  O  O   . HOH T 7 .   ? 27.153  82.217  40.092 1   45.86  ? 422 HOH L O   1 
HETATM 9816  O  O   . HOH T 7 .   ? 46.014  47.882  21.035 1   31.71  ? 423 HOH L O   1 
HETATM 9817  O  O   . HOH T 7 .   ? 30.707  86.469  49.205 1   52.82  ? 424 HOH L O   1 
HETATM 9818  O  O   . HOH T 7 .   ? 34.417  35.556  9.996  1   52.28  ? 425 HOH L O   1 
HETATM 9819  O  O   . HOH T 7 .   ? 17.176  75.722  45.287 1   48.72  ? 426 HOH L O   1 
HETATM 9820  O  O   . HOH T 7 .   ? 29.309  70.222  55.162 1   42.69  ? 427 HOH L O   1 
HETATM 9821  O  O   . HOH T 7 .   ? 25.123  16.475  31.31  1   62.07  ? 428 HOH L O   1 
HETATM 9822  O  O   . HOH T 7 .   ? 21.2    79.903  53.186 1   50.13  ? 429 HOH L O   1 
HETATM 9823  O  O   . HOH T 7 .   ? 40.97   64.659  39.145 1   41.46  ? 430 HOH L O   1 
HETATM 9824  O  O   . HOH T 7 .   ? 21.786  74.303  42.583 1   45.46  ? 431 HOH L O   1 
HETATM 9825  O  O   . HOH T 7 .   ? 39.567  37.162  30.767 1   40.85  ? 432 HOH L O   1 
HETATM 9826  O  O   . HOH T 7 .   ? 36.779  85.804  49.844 1   56.33  ? 433 HOH L O   1 
HETATM 9827  O  O   . HOH T 7 .   ? 24.248  44.645  27.068 1   50.86  ? 434 HOH L O   1 
HETATM 9828  O  O   . HOH T 7 .   ? 20.075  43.885  12.558 1   43.17  ? 435 HOH L O   1 
HETATM 9829  O  O   . HOH T 7 .   ? 40.753  42.743  9.172  1   36.31  ? 436 HOH L O   1 
HETATM 9830  O  O   . HOH T 7 .   ? 30.902  43.133  7.284  1   46.74  ? 437 HOH L O   1 
HETATM 9831  O  O   . HOH T 7 .   ? 22.384  78.04   56.536 1   59.05  ? 438 HOH L O   1 
HETATM 9832  O  O   . HOH T 7 .   ? 36.747  85.53   43.093 1   49.93  ? 439 HOH L O   1 
HETATM 9833  O  O   . HOH T 7 .   ? 34.441  46.798  6.188  1   52.38  ? 440 HOH L O   1 
HETATM 9834  O  O   . HOH T 7 .   ? 31.586  14.447  20.336 1   50.48  ? 441 HOH L O   1 
HETATM 9835  O  O   . HOH T 7 .   ? 28.486  74.205  59.119 1   54.69  ? 442 HOH L O   1 
HETATM 9836  O  O   . HOH T 7 .   ? 26.976  45.6    18.362 1   49.81  ? 443 HOH L O   1 
HETATM 9837  O  O   . HOH T 7 .   ? 21.991  83.698  45.03  1   56     ? 444 HOH L O   1 
HETATM 9838  O  O   . HOH T 7 .   ? 32.407  25.71   13.762 1   40.89  ? 445 HOH L O   1 
HETATM 9839  O  O   . HOH T 7 .   ? 36.214  20.346  16.104 1   61.68  ? 446 HOH L O   1 
HETATM 9840  O  O   . HOH T 7 .   ? 34.013  65.051  50.608 1   32.72  ? 447 HOH L O   1 
HETATM 9841  O  O   . HOH T 7 .   ? 25.688  23.582  15.867 1   62     ? 448 HOH L O   1 
HETATM 9842  O  O   . HOH T 7 .   ? 22.727  79.076  46.328 1   47.55  ? 449 HOH L O   1 
HETATM 9843  O  O   . HOH T 7 .   ? 23.182  22.281  15.909 1   53.97  ? 450 HOH L O   1 
HETATM 9844  O  O   . HOH T 7 .   ? 41.512  39.731  16.633 1   40.75  ? 451 HOH L O   1 
HETATM 9845  O  O   . HOH T 7 .   ? 27.258  67.528  31.8   1   37.25  ? 452 HOH L O   1 
HETATM 9846  O  O   . HOH T 7 .   ? 38.425  61.505  45.009 1   47.14  ? 453 HOH L O   1 
HETATM 9847  O  O   . HOH T 7 .   ? 37.833  88.646  50.461 1   64.38  ? 454 HOH L O   1 
HETATM 9848  O  O   . HOH T 7 .   ? 31.197  79.925  34.391 1   38.64  ? 455 HOH L O   1 
HETATM 9849  O  O   . HOH T 7 .   ? 39.114  82.792  39.227 1   48.97  ? 456 HOH L O   1 
HETATM 9850  O  O   . HOH T 7 .   ? 31.945  70.399  54.626 1   44.93  ? 457 HOH L O   1 
HETATM 9851  O  O   . HOH T 7 .   ? 37.258  77.722  30.044 1   37.35  ? 458 HOH L O   1 
HETATM 9852  O  O   . HOH T 7 .   ? 42.963  60.819  34.776 1   46.21  ? 459 HOH L O   1 
HETATM 9853  O  O   . HOH T 7 .   ? 42.162  21.148  21.162 1   49.52  ? 460 HOH L O   1 
HETATM 9854  O  O   . HOH T 7 .   ? 43.924  34.42   22.461 1   50.83  ? 461 HOH L O   1 
HETATM 9855  O  O   . HOH T 7 .   ? 41.393  36.034  20.552 1   50.33  ? 462 HOH L O   1 
HETATM 9856  O  O   . HOH T 7 .   ? 35.800  80.576  55.150 1   43.4   ? 463 HOH L O   1 
HETATM 9857  O  O   . HOH T 7 .   ? 39.718  55.634  26.542 1   31.37  ? 464 HOH L O   1 
HETATM 9858  O  O   . HOH T 7 .   ? 19.107  38.733  22.101 1   41.47  ? 465 HOH L O   1 
HETATM 9859  O  O   . HOH T 7 .   ? 42.167  57.636  19.065 1   46.18  ? 466 HOH L O   1 
HETATM 9860  O  O   . HOH T 7 .   ? 31.267  72.962  28.556 1   54.82  ? 467 HOH L O   1 
HETATM 9861  O  O   . HOH T 7 .   ? 31.361  64.364  52.222 1   50.67  ? 468 HOH L O   1 
HETATM 9862  O  O   . HOH T 7 .   ? 39.445  65.217  50.8   1   46.61  ? 469 HOH L O   1 
HETATM 9863  O  O   . HOH T 7 .   ? 38.309  77.614  53.117 1   77.58  ? 470 HOH L O   1 
HETATM 9864  O  O   . HOH T 7 .   ? 44.042  74.028  36.126 1   53.99  ? 471 HOH L O   1 
HETATM 9865  O  O   . HOH T 7 .   ? 23.092  31.926  12.106 1   55.62  ? 472 HOH L O   1 
HETATM 9866  O  O   . HOH T 7 .   ? 40.436  86.174  42.979 1   52.06  ? 473 HOH L O   1 
HETATM 9867  O  O   . HOH T 7 .   ? 20.364  43.9    27.226 1   43.79  ? 474 HOH L O   1 
HETATM 9868  O  O   . HOH T 7 .   ? 30.804  68.763  24.645 1   55.58  ? 475 HOH L O   1 
HETATM 9869  O  O   . HOH T 7 .   ? 24.116  43.708  18.355 1   50.93  ? 476 HOH L O   1 
HETATM 9870  O  O   . HOH T 7 .   ? 41.51   68.28   43.402 1   57.7   ? 477 HOH L O   1 
HETATM 9871  O  O   . HOH T 7 .   ? 38.393  28.187  17.532 1   61.06  ? 478 HOH L O   1 
HETATM 9872  O  O   . HOH T 7 .   ? 16.886  71.02   57.353 1   52.11  ? 479 HOH L O   1 
HETATM 9873  O  O   . HOH T 7 .   ? 28.579  46.606  33.372 1   49.1   ? 480 HOH L O   1 
HETATM 9874  O  O   . HOH T 7 .   ? 41.967  47.077  9.408  1   50.1   ? 481 HOH L O   1 
HETATM 9875  O  O   . HOH T 7 .   ? 45.646  59.832  24.888 1   53.34  ? 482 HOH L O   1 
HETATM 9876  O  O   . HOH T 7 .   ? 22.601  88.824  41.553 1   62.06  ? 483 HOH L O   1 
HETATM 9877  O  O   . HOH T 7 .   ? 24.051  75.433  36.207 1   47.67  ? 484 HOH L O   1 
HETATM 9878  O  O   . HOH T 7 .   ? 36.038  41.299  31.215 1   42.31  ? 485 HOH L O   1 
HETATM 9879  O  O   . HOH T 7 .   ? 20.574  76.5    58.92  1   53.84  ? 486 HOH L O   1 
HETATM 9880  O  O   . HOH T 7 .   ? 45.404  66.411  30.755 1   50.38  ? 487 HOH L O   1 
HETATM 9881  O  O   . HOH T 7 .   ? 43.784  33.719  25.884 1   52.81  ? 488 HOH L O   1 
HETATM 9882  O  O   . HOH T 7 .   ? 42.32   56.754  28.378 1   49.77  ? 489 HOH L O   1 
HETATM 9883  O  O   . HOH T 7 .   ? 36.119  83.653  38.566 1   52.75  ? 490 HOH L O   1 
HETATM 9884  O  O   . HOH T 7 .   ? 44.38   63.809  32.092 1   48.63  ? 491 HOH L O   1 
HETATM 9885  O  O   . HOH T 7 .   ? 32.269  66.876  54.649 1   53.87  ? 492 HOH L O   1 
HETATM 9886  O  O   . HOH T 7 .   ? 27.968  31.221  10.68  1   57.03  ? 493 HOH L O   1 
HETATM 9887  O  O   . HOH T 7 .   ? 34.873  66.129  53.025 1   45.03  ? 494 HOH L O   1 
HETATM 9888  O  O   . HOH T 7 .   ? 28.093  28.086  10.452 1   56.32  ? 495 HOH L O   1 
HETATM 9889  O  O   . HOH T 7 .   ? 32.715  75.067  27.361 1   47.26  ? 496 HOH L O   1 
HETATM 9890  O  O   . HOH T 7 .   ? 29.927  23.648  14.837 1   47.76  ? 497 HOH L O   1 
HETATM 9891  O  O   . HOH U 7 .   ? 10.083  0.358   43.678 1   37.9   ? 601 HOH P O   1 
HETATM 9892  O  O   . HOH U 7 .   ? -10.721 11.801  54.927 1   46.98  ? 602 HOH P O   1 
HETATM 9893  O  O   . HOH U 7 .   ? 21.313  0.5     24.539 1   55.95  ? 603 HOH P O   1 
HETATM 9894  O  O   . HOH U 7 .   ? 7.847   16.735  26.403 1   42.66  ? 604 HOH P O   1 
HETATM 9895  O  O   . HOH U 7 .   ? 21.131  19.656  17.343 1   46.91  ? 605 HOH P O   1 
HETATM 9896  O  O   . HOH U 7 .   ? 17.034  14.998  15.486 1   42.47  ? 606 HOH P O   1 
HETATM 9897  O  O   . HOH U 7 .   ? 9.101   -7.667  37.681 1   49.61  ? 607 HOH P O   1 
HETATM 9898  O  O   . HOH U 7 .   ? -23.243 3.216   46.165 1   61.76  ? 608 HOH P O   1 
HETATM 9899  O  O   . HOH U 7 .   ? -3.15   11.841  36.633 1   52.48  ? 609 HOH P O   1 
HETATM 9900  O  O   . HOH U 7 .   ? 3.871   14.494  29.726 1   45.12  ? 610 HOH P O   1 
HETATM 9901  O  O   . HOH U 7 .   ? 8.974   7.565   18.89  1   47.96  ? 611 HOH P O   1 
HETATM 9902  O  O   . HOH U 7 .   ? 15.937  6.776   39.026 1   37.18  ? 612 HOH P O   1 
HETATM 9903  O  O   . HOH U 7 .   ? 3.121   11.218  30.026 1   50.53  ? 613 HOH P O   1 
HETATM 9904  O  O   . HOH U 7 .   ? 25.978  10.966  11.487 1   56.85  ? 614 HOH P O   1 
HETATM 9905  O  O   . HOH U 7 .   ? 8.195   23.765  26.874 1   53.04  ? 615 HOH P O   1 
HETATM 9906  O  O   . HOH U 7 .   ? 12.136  24.057  27.01  1   49.43  ? 616 HOH P O   1 
HETATM 9907  O  O   . HOH U 7 .   ? 20.193  15.163  34.758 1   41.45  ? 617 HOH P O   1 
HETATM 9908  O  O   . HOH U 7 .   ? 1.831   6.562   30.506 1   47.09  ? 618 HOH P O   1 
HETATM 9909  O  O   . HOH U 7 .   ? -0.609  11.298  52.138 0.5 40.01  ? 619 HOH P O   1 
HETATM 9910  O  O   . HOH U 7 .   ? 21.401  11.988  34.924 1   47.13  ? 620 HOH P O   1 
HETATM 9911  O  O   . HOH U 7 .   ? -7.457  4.671   48.711 1   64.54  ? 621 HOH P O   1 
HETATM 9912  O  O   . HOH U 7 .   ? 3.242   10.728  23.726 1   55.37  ? 622 HOH P O   1 
HETATM 9913  O  O   . HOH U 7 .   ? 4.185   18.71   25.272 1   47.71  ? 623 HOH P O   1 
HETATM 9914  O  O   . HOH U 7 .   ? 30.534  18.664  17.627 1   48.39  ? 624 HOH P O   1 
HETATM 9915  O  O   . HOH U 7 .   ? -1.128  -6.065  25.953 1   51.47  ? 625 HOH P O   1 
HETATM 9916  O  O   . HOH U 7 .   ? 1.53    5.787   51.952 1   59.11  ? 626 HOH P O   1 
HETATM 9917  O  O   . HOH U 7 .   ? 9.308   -2.858  45.966 1   57.97  ? 627 HOH P O   1 
HETATM 9918  O  O   . HOH U 7 .   ? 15.167  5.341   10.609 1   65.93  ? 628 HOH P O   1 
HETATM 9919  O  O   . HOH U 7 .   ? 13.266  13.098  43.188 1   53.16  ? 629 HOH P O   1 
HETATM 9920  O  O   . HOH U 7 .   ? 14.347  15.036  17.49  1   56.46  ? 630 HOH P O   1 
HETATM 9921  O  O   . HOH U 7 .   ? 1.946   8.351   21.618 1   48.08  ? 631 HOH P O   1 
HETATM 9922  O  O   . HOH U 7 .   ? 16.447  15.809  13.084 1   48.15  ? 632 HOH P O   1 
HETATM 9923  O  O   . HOH U 7 .   ? 22.396  10.391  37.621 1   58.33  ? 633 HOH P O   1 
HETATM 9924  O  O   . HOH V 7 .   ? 8.069   -16.614 26.389 1   43.09  ? 501 HOH Q O   1 
HETATM 9925  O  O   . HOH V 7 .   ? 21.149  -0.505  27.98  1   36.18  ? 502 HOH Q O   1 
HETATM 9926  O  O   . HOH V 7 .   ? 8.986   7.73    14.937 1   49.8   ? 503 HOH Q O   1 
HETATM 9927  O  O   . HOH V 7 .   ? 10.584  -9.841  34.514 1   43.79  ? 504 HOH Q O   1 
HETATM 9928  O  O   . HOH V 7 .   ? 16.908  -15.151 36.899 1   43.57  ? 505 HOH Q O   1 
HETATM 9929  O  O   . HOH V 7 .   ? 2.552   -26.227 9.005  1   56.21  ? 506 HOH Q O   1 
HETATM 9930  O  O   . HOH V 7 .   ? 8.997   -7.569  33.632 1   35.76  ? 507 HOH Q O   1 
HETATM 9931  O  O   . HOH V 7 .   ? 0.749   0.017   26.395 1   16.77  ? 508 HOH Q O   1 
HETATM 9932  O  O   . HOH V 7 .   ? 10.651  -6.462  40.039 1   38.66  ? 509 HOH Q O   1 
HETATM 9933  O  O   . HOH V 7 .   ? 0.535   6.182   19.571 1   43.76  ? 510 HOH Q O   1 
HETATM 9934  O  O   . HOH V 7 .   ? 15.349  -12.589 11.23  1   50.26  ? 511 HOH Q O   1 
HETATM 9935  O  O   . HOH V 7 .   ? 20.613  -19.764 35.555 1   54.33  ? 512 HOH Q O   1 
HETATM 9936  O  O   . HOH V 7 .   ? 3.614   -14.446 22.846 1   48.74  ? 513 HOH Q O   1 
HETATM 9937  O  O   . HOH V 7 .   ? 26.419  -11.285 41.389 1   55.68  ? 514 HOH Q O   1 
HETATM 9938  O  O   . HOH V 7 .   ? 11.979  -23.89  25.647 1   42.44  ? 515 HOH Q O   1 
HETATM 9939  O  O   . HOH V 7 .   ? 5.19    -19.276 8.722  1   53.54  ? 516 HOH Q O   1 
HETATM 9940  O  O   . HOH V 7 .   ? 21.47   -11.896 18.032 1   40.33  ? 517 HOH Q O   1 
HETATM 9941  O  O   . HOH V 7 .   ? 15.804  -6.853  13.403 1   46.27  ? 518 HOH Q O   1 
HETATM 9942  O  O   . HOH V 7 .   ? 16.047  -5.166  41.926 1   55.45  ? 519 HOH Q O   1 
HETATM 9943  O  O   . HOH V 7 .   ? 9.425   3.011   6.616  1   57.08  ? 520 HOH Q O   1 
HETATM 9944  O  O   . HOH V 7 .   ? 20.317  -15.292 17.774 1   37.41  ? 521 HOH Q O   1 
HETATM 9945  O  O   . HOH V 7 .   ? 12.893  -27.995 28.675 1   56.68  ? 522 HOH Q O   1 
HETATM 9946  O  O   . HOH V 7 .   ? 7.598   -22.16  29.081 1   55.07  ? 523 HOH Q O   1 
HETATM 9947  O  O   . HOH V 7 .   ? 3.143   -14.621 7.682  1   50.71  ? 524 HOH Q O   1 
HETATM 9948  O  O   . HOH V 7 .   ? 27.117  3.683   31.088 1   46.16  ? 525 HOH Q O   1 
HETATM 9949  O  O   . HOH V 7 .   ? 8.798   -12.544 38.426 1   49.39  ? 526 HOH Q O   1 
HETATM 9950  O  O   . HOH V 7 .   ? 2.401   -9.01   29.191 1   31.86  ? 527 HOH Q O   1 
HETATM 9951  O  O   . HOH V 7 .   ? -1.608  3.885   19.35  1   39.76  ? 528 HOH Q O   1 
HETATM 9952  O  O   . HOH V 7 .   ? -0.377  -7.241  19.312 1   45.93  ? 529 HOH Q O   1 
HETATM 9953  O  O   . HOH V 7 .   ? 2.812   -10.683 22.928 1   50.06  ? 530 HOH Q O   1 
HETATM 9954  O  O   . HOH V 7 .   ? 14.404  -14.885 35.406 1   50.88  ? 531 HOH Q O   1 
HETATM 9955  O  O   . HOH V 7 .   ? 3.089   -11.696 28.189 1   42.02  ? 532 HOH Q O   1 
HETATM 9956  O  O   . HOH V 7 .   ? 2.722   9.26    18.963 1   62.81  ? 533 HOH Q O   1 
HETATM 9957  O  O   . HOH V 7 .   ? 10.547  10.272  14.844 1   43.67  ? 534 HOH Q O   1 
HETATM 9958  O  O   . HOH V 7 .   ? 10.6    -10.607 38.001 1   51.75  ? 535 HOH Q O   1 
HETATM 9959  O  O   . HOH V 7 .   ? 11.338  -21.488 33.272 1   50.27  ? 536 HOH Q O   1 
HETATM 9960  O  O   . HOH V 7 .   ? 16.316  -15.755 39.548 1   46.98  ? 537 HOH Q O   1 
HETATM 9961  O  O   . HOH V 7 .   ? 0.276   9.089   16.636 1   53.91  ? 538 HOH Q O   1 
HETATM 9962  O  O   . HOH V 7 .   ? 10.872  -19.344 34.698 1   45.58  ? 539 HOH Q O   1 
HETATM 9963  O  O   . HOH W 7 .   ? 23.046  -46.285 5.085  1   28.67  ? 401 HOH A O   1 
HETATM 9964  O  O   . HOH W 7 .   ? 19.35   -74.002 8.984  1   38     ? 402 HOH A O   1 
HETATM 9965  O  O   . HOH W 7 .   ? 13.67   -33.853 27.443 1   47.96  ? 403 HOH A O   1 
HETATM 9966  O  O   . HOH W 7 .   ? 12.581  -37.771 4.394  1   51.74  ? 404 HOH A O   1 
HETATM 9967  O  O   . HOH W 7 .   ? 28.282  -22.177 8.949  1   44.86  ? 405 HOH A O   1 
HETATM 9968  O  O   . HOH W 7 .   ? 14.307  -86.446 7.655  1   53.5   ? 406 HOH A O   1 
HETATM 9969  O  O   . HOH W 7 .   ? 31.903  -43.714 18     1   38.17  ? 407 HOH A O   1 
HETATM 9970  O  O   . HOH W 7 .   ? 32.286  -44.962 -3.135 1   52.7   ? 408 HOH A O   1 
HETATM 9971  O  O   . HOH W 7 .   ? 12.731  -73.719 16.329 1   56.67  ? 409 HOH A O   1 
HETATM 9972  O  O   . HOH W 7 .   ? 31.879  -55.541 12.68  1   50.25  ? 410 HOH A O   1 
HETATM 9973  O  O   . HOH W 7 .   ? 9.942   -71.935 14.737 1   40.18  ? 411 HOH A O   1 
HETATM 9974  O  O   . HOH W 7 .   ? 13.561  -45.521 10.489 1   45.06  ? 412 HOH A O   1 
HETATM 9975  O  O   . HOH W 7 .   ? 17.163  -42.582 21.818 1   45.56  ? 413 HOH A O   1 
HETATM 9976  O  O   . HOH W 7 .   ? 13.072  -55.64  12.122 1   38.34  ? 414 HOH A O   1 
HETATM 9977  O  O   . HOH W 7 .   ? 14.392  -23.432 8.208  1   48.84  ? 415 HOH A O   1 
HETATM 9978  O  O   . HOH W 7 .   ? 7.891   -42.903 23.871 1   56.59  ? 416 HOH A O   1 
HETATM 9979  O  O   . HOH W 7 .   ? 22.557  -45.248 17.685 1   40.74  ? 417 HOH A O   1 
HETATM 9980  O  O   . HOH W 7 .   ? 31.305  -50.171 3.158  1   36.28  ? 418 HOH A O   1 
HETATM 9981  O  O   . HOH W 7 .   ? 31.481  -37.894 13.048 1   42.7   ? 419 HOH A O   1 
HETATM 9982  O  O   . HOH W 7 .   ? 31.783  -41.032 -7.482 1   48.06  ? 420 HOH A O   1 
HETATM 9983  O  O   . HOH W 7 .   ? 24.599  -55.386 16.728 1   54.36  ? 421 HOH A O   1 
HETATM 9984  O  O   . HOH W 7 .   ? 15.071  -73.983 9.894  1   59.03  ? 422 HOH A O   1 
HETATM 9985  O  O   . HOH W 7 .   ? 15.782  -44.9   9.15   1   59.41  ? 423 HOH A O   1 
HETATM 9986  O  O   . HOH W 7 .   ? 22.783  -32.505 -4.816 1   51.81  ? 424 HOH A O   1 
HETATM 9987  O  O   . HOH W 7 .   ? 34.114  -56.636 9.309  1   36.56  ? 425 HOH A O   1 
HETATM 9988  O  O   . HOH W 7 .   ? 18.983  -55.426 15.311 1   37.25  ? 426 HOH A O   1 
HETATM 9989  O  O   . HOH W 7 .   ? 13.467  -40.734 21.798 1   46.56  ? 427 HOH A O   1 
HETATM 9990  O  O   . HOH W 7 .   ? 6.602   -31.785 4.552  1   59.32  ? 428 HOH A O   1 
HETATM 9991  O  O   . HOH W 7 .   ? 21.162  -78.171 22.603 1   48.04  ? 429 HOH A O   1 
HETATM 9992  O  O   . HOH W 7 .   ? 4.766   -74.541 16.425 1   58.35  ? 430 HOH A O   1 
HETATM 9993  O  O   . HOH W 7 .   ? 21.631  -57.93  20.504 1   38.63  ? 431 HOH A O   1 
HETATM 9994  O  O   . HOH W 7 .   ? 11.464  -24.226 8.67   1   44.91  ? 432 HOH A O   1 
HETATM 9995  O  O   . HOH W 7 .   ? 14.341  -27.892 2.832  1   42.79  ? 433 HOH A O   1 
HETATM 9996  O  O   . HOH W 7 .   ? 27.376  -48.914 5.034  1   32.08  ? 434 HOH A O   1 
HETATM 9997  O  O   . HOH W 7 .   ? 5.286   -29.112 24.141 1   41.19  ? 435 HOH A O   1 
HETATM 9998  O  O   . HOH W 7 .   ? 32.104  -43.518 2.844  1   43.6   ? 436 HOH A O   1 
HETATM 9999  O  O   . HOH W 7 .   ? 30.756  -27.689 3.135  1   60.17  ? 437 HOH A O   1 
HETATM 10000 O  O   . HOH W 7 .   ? 8.827   -62.292 4.057  1   39.68  ? 438 HOH A O   1 
HETATM 10001 O  O   . HOH W 7 .   ? 10.983  -65.563 26.45  1   41.42  ? 439 HOH A O   1 
HETATM 10002 O  O   . HOH W 7 .   ? 27.42   -57.426 20.529 1   55.44  ? 440 HOH A O   1 
HETATM 10003 O  O   . HOH W 7 .   ? 25.038  -65.318 22.414 1   47.44  ? 441 HOH A O   1 
HETATM 10004 O  O   . HOH W 7 .   ? 15.4    -63.434 1.57   1   59.08  ? 442 HOH A O   1 
HETATM 10005 O  O   . HOH W 7 .   ? 7.526   -64.839 21.924 1   33.17  ? 443 HOH A O   1 
HETATM 10006 O  O   . HOH W 7 .   ? 15.799  -28.566 32.23  1   61.99  ? 444 HOH A O   1 
HETATM 10007 O  O   . HOH W 7 .   ? 21.45   -47.931 -5.669 1   48.12  ? 445 HOH A O   1 
HETATM 10008 O  O   . HOH W 7 .   ? 29.312  -52.662 -2.302 1   50.8   ? 446 HOH A O   1 
HETATM 10009 O  O   . HOH W 7 .   ? 2.273   -35.662 19.956 1   45.35  ? 447 HOH A O   1 
HETATM 10010 O  O   . HOH W 7 .   ? 2.625   -35.738 17.063 1   40.1   ? 448 HOH A O   1 
HETATM 10011 O  O   . HOH W 7 .   ? 21.73   -44.34  -4.505 1   59.58  ? 449 HOH A O   1 
HETATM 10012 O  O   . HOH W 7 .   ? 23.629  -54.706 -6.287 1   48.52  ? 450 HOH A O   1 
HETATM 10013 O  O   . HOH W 7 .   ? 15.878  -65.853 0.847  1   56.31  ? 451 HOH A O   1 
HETATM 10014 O  O   . HOH W 7 .   ? 24.825  -50.514 11.916 1   62.93  ? 452 HOH A O   1 
HETATM 10015 O  O   . HOH W 7 .   ? 3.896   -40.484 23.759 1   55.64  ? 453 HOH A O   1 
HETATM 10016 O  O   . HOH W 7 .   ? 33.066  -32.454 15.84  1   52.17  ? 454 HOH A O   1 
HETATM 10017 O  O   . HOH W 7 .   ? 24.767  -62.068 24.843 1   58.64  ? 455 HOH A O   1 
HETATM 10018 O  O   . HOH W 7 .   ? 0.644   -34.3   14.208 1   57.44  ? 456 HOH A O   1 
HETATM 10019 O  O   . HOH W 7 .   ? 18.666  -55.47  -4.859 1   49.29  ? 457 HOH A O   1 
HETATM 10020 O  O   . HOH W 7 .   ? 32.514  -47.748 -4.51  1   64.6   ? 458 HOH A O   1 
HETATM 10021 O  O   . HOH W 7 .   ? 22.16   -54.931 18.303 1   44.36  ? 459 HOH A O   1 
HETATM 10022 O  O   . HOH W 7 .   ? 12.217  -67.922 25.557 1   45.07  ? 460 HOH A O   1 
HETATM 10023 O  O   . HOH W 7 .   ? 30.93   -46.303 4.19   1   64.01  ? 461 HOH A O   1 
HETATM 10024 O  O   . HOH X 7 .   ? 36.627  -58.365 9.091  1   48.28  ? 401 HOH B O   1 
HETATM 10025 O  O   . HOH X 7 .   ? 20.563  -19.861 31.106 1   34.81  ? 402 HOH B O   1 
HETATM 10026 O  O   . HOH X 7 .   ? 30.445  -53.507 38.313 1   55.8   ? 403 HOH B O   1 
HETATM 10027 O  O   . HOH X 7 .   ? 22.362  -83.6   8.211  1   51.39  ? 404 HOH B O   1 
HETATM 10028 O  O   . HOH X 7 .   ? 41.331  -32.096 27.942 1   50.72  ? 405 HOH B O   1 
HETATM 10029 O  O   . HOH X 7 .   ? 42.218  -70.742 16.908 1   30.35  ? 406 HOH B O   1 
HETATM 10030 O  O   . HOH X 7 .   ? 37.012  -80.757 10.872 1   39.35  ? 407 HOH B O   1 
HETATM 10031 O  O   . HOH X 7 .   ? 45.554  -47.791 32.002 1   39.88  ? 408 HOH B O   1 
HETATM 10032 O  O   . HOH X 7 .   ? 42.912  -54.621 33.921 1   46.85  ? 409 HOH B O   1 
HETATM 10033 O  O   . HOH X 7 .   ? 29.202  -69.71  -0.727 1   44     ? 410 HOH B O   1 
HETATM 10034 O  O   . HOH X 7 .   ? 37.755  -53.118 28.672 1   52.47  ? 411 HOH B O   1 
HETATM 10035 O  O   . HOH X 7 .   ? 22.555  -42.955 33.958 1   53.59  ? 412 HOH B O   1 
HETATM 10036 O  O   . HOH X 7 .   ? 40.983  -34.608 34.433 1   51.54  ? 413 HOH B O   1 
HETATM 10037 O  O   . HOH X 7 .   ? 30.836  -26.131 15.65  1   50.15  ? 414 HOH B O   1 
HETATM 10038 O  O   . HOH X 7 .   ? 24.12   -44.403 25.587 1   52.46  ? 415 HOH B O   1 
HETATM 10039 O  O   . HOH X 7 .   ? 33.031  -65.969 4.252  1   35.09  ? 416 HOH B O   1 
HETATM 10040 O  O   . HOH X 7 .   ? 25.531  -80.496 10.39  1   47.24  ? 417 HOH B O   1 
HETATM 10041 O  O   . HOH X 7 .   ? 40.491  -46.457 27.673 1   50.61  ? 418 HOH B O   1 
HETATM 10042 O  O   . HOH X 7 .   ? 20.672  -43.726 25.056 1   39.97  ? 419 HOH B O   1 
HETATM 10043 O  O   . HOH X 7 .   ? 30.226  -59.725 15.146 1   39.29  ? 420 HOH B O   1 
HETATM 10044 O  O   . HOH X 7 .   ? 31.775  -37.081 41.393 1   49.96  ? 421 HOH B O   1 
HETATM 10045 O  O   . HOH X 7 .   ? 26.974  -45.812 34.317 1   43.92  ? 422 HOH B O   1 
HETATM 10046 O  O   . HOH X 7 .   ? 23.229  -31.733 40.762 1   54.48  ? 423 HOH B O   1 
HETATM 10047 O  O   . HOH X 7 .   ? 11.651  -70.76  6.273  1   58.54  ? 424 HOH B O   1 
HETATM 10048 O  O   . HOH X 7 .   ? 25.51   -66.87  0.637  1   45.67  ? 425 HOH B O   1 
HETATM 10049 O  O   . HOH X 7 .   ? 33.634  -32.57  39.588 1   44.59  ? 426 HOH B O   1 
HETATM 10050 O  O   . HOH X 7 .   ? 39.931  -68.265 27.684 1   47.03  ? 427 HOH B O   1 
HETATM 10051 O  O   . HOH X 7 .   ? 33.812  -64.457 1.774  1   54.09  ? 428 HOH B O   1 
HETATM 10052 O  O   . HOH X 7 .   ? 31.247  -79.732 18.121 1   30.31  ? 429 HOH B O   1 
HETATM 10053 O  O   . HOH X 7 .   ? 30.802  -43.528 45.093 1   57.84  ? 430 HOH B O   1 
HETATM 10054 O  O   . HOH X 7 .   ? 39.026  -60.803 15.734 1   54.55  ? 431 HOH B O   1 
HETATM 10055 O  O   . HOH X 7 .   ? 21.571  -80.245 -0.27  1   46.7   ? 432 HOH B O   1 
HETATM 10056 O  O   . HOH X 7 .   ? 25.252  -23.633 37.005 1   56.33  ? 433 HOH B O   1 
HETATM 10057 O  O   . HOH X 7 .   ? 22.729  -78.935 6.758  1   39.51  ? 434 HOH B O   1 
HETATM 10058 O  O   . HOH X 7 .   ? 35.67   -20.631 36.51  1   59.14  ? 435 HOH B O   1 
HETATM 10059 O  O   . HOH X 7 .   ? 30.949  -72.892 23.804 1   54.29  ? 436 HOH B O   1 
HETATM 10060 O  O   . HOH X 7 .   ? 39.505  -54.769 21.895 1   51.17  ? 437 HOH B O   1 
HETATM 10061 O  O   . HOH X 7 .   ? 41.459  -36.259 32.304 1   55.05  ? 438 HOH B O   1 
HETATM 10062 O  O   . HOH X 7 .   ? 39.656  -55.703 26.327 1   39.39  ? 439 HOH B O   1 
HETATM 10063 O  O   . HOH X 7 .   ? 34.23   -46.476 46.46  1   49.83  ? 440 HOH B O   1 
HETATM 10064 O  O   . HOH X 7 .   ? 18.19   -76.246 7.439  1   44.92  ? 441 HOH B O   1 
HETATM 10065 O  O   . HOH X 7 .   ? 40.655  -42.571 43.682 1   36.8   ? 442 HOH B O   1 
HETATM 10066 O  O   . HOH X 7 .   ? 36.727  -83.666 13.309 1   51.18  ? 443 HOH B O   1 
HETATM 10067 O  O   . HOH X 7 .   ? 30.865  -68.548 28.045 1   51.88  ? 444 HOH B O   1 
HETATM 10068 O  O   . HOH X 7 .   ? 32.26   -25.705 39.179 1   37.67  ? 445 HOH B O   1 
HETATM 10069 O  O   . HOH X 7 .   ? 38.817  -61.236 8.034  1   37.27  ? 446 HOH B O   1 
HETATM 10070 O  O   . HOH X 7 .   ? 34.438  -56     11.89  1   37.2   ? 447 HOH B O   1 
HETATM 10071 O  O   . HOH X 7 .   ? 28.192  -72.758 23.703 1   47     ? 448 HOH B O   1 
HETATM 10072 O  O   . HOH X 7 .   ? 42.644  -60.179 17.889 1   48.85  ? 449 HOH B O   1 
HETATM 10073 O  O   . HOH X 7 .   ? 36.803  -77.685 22.875 1   48.68  ? 450 HOH B O   1 
HETATM 10074 O  O   . HOH X 7 .   ? 41.84   -21.658 31.976 1   50.91  ? 451 HOH B O   1 
HETATM 10075 O  O   . HOH X 7 .   ? 32.337  -70.275 -1.959 1   43.1   ? 452 HOH B O   1 
HETATM 10076 O  O   . HOH X 7 .   ? 41.723  -37.605 39.111 1   52.14  ? 453 HOH B O   1 
HETATM 10077 O  O   . HOH X 7 .   ? 32.999  -51.144 41.805 1   64.1   ? 454 HOH B O   1 
HETATM 10078 O  O   . HOH X 7 .   ? 30.759  -82.363 16.847 1   45.63  ? 455 HOH B O   1 
HETATM 10079 O  O   . HOH X 7 .   ? 34.092  -29.826 14.04  1   45.29  ? 456 HOH B O   1 
HETATM 10080 O  O   . HOH X 7 .   ? 35.745  -41.006 19.855 1   38.93  ? 457 HOH B O   1 
HETATM 10081 O  O   . HOH X 7 .   ? 18.855  -38.643 30.886 1   36.93  ? 458 HOH B O   1 
HETATM 10082 O  O   . HOH X 7 .   ? 32.576  -17.959 18.345 1   54.88  ? 459 HOH B O   1 
HETATM 10083 O  O   . HOH X 7 .   ? 39.606  -64.736 2.684  1   56.03  ? 460 HOH B O   1 
HETATM 10084 O  O   . HOH X 7 .   ? 36.292  -80.168 -2.130 1   46.15  ? 461 HOH B O   1 
HETATM 10085 O  O   . HOH X 7 .   ? 41.757  -34.484 40.155 1   54.92  ? 462 HOH B O   1 
HETATM 10086 O  O   . HOH X 7 .   ? 28.063  -40.837 46.371 1   47.06  ? 463 HOH B O   1 
HETATM 10087 O  O   . HOH X 7 .   ? 41.782  -39.697 36.007 1   52.06  ? 464 HOH B O   1 
HETATM 10088 O  O   . HOH X 7 .   ? 39.591  -59.159 12.2   1   48.18  ? 465 HOH B O   1 
HETATM 10089 O  O   . HOH X 7 .   ? 25.6    -67.897 21.057 1   50.5   ? 466 HOH B O   1 
HETATM 10090 O  O   . HOH X 7 .   ? 37.637  -27.992 35.958 1   46.46  ? 467 HOH B O   1 
HETATM 10091 O  O   . HOH X 7 .   ? 39.415  -76.878 -1.577 1   55.33  ? 468 HOH B O   1 
HETATM 10092 O  O   . HOH X 7 .   ? 24.709  -62.573 27.94  1   64.23  ? 469 HOH B O   1 
HETATM 10093 O  O   . HOH X 7 .   ? 43.896  -33.908 26.664 1   50.8   ? 470 HOH B O   1 
HETATM 10094 O  O   . HOH X 7 .   ? 24.614  -44.222 34.515 1   43.39  ? 471 HOH B O   1 
HETATM 10095 O  O   . HOH X 7 .   ? 44.247  -66.949 2.155  1   48.64  ? 472 HOH B O   1 
HETATM 10096 O  O   . HOH X 7 .   ? 22.436  -44.872 27.714 1   50.59  ? 473 HOH B O   1 
HETATM 10097 O  O   . HOH X 7 .   ? 46.565  -31.889 26.731 1   52.4   ? 474 HOH B O   1 
# 
