data_8R2Z
# 
_entry.id   8R2Z 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R2Z         pdb_00008r2z 10.2210/pdb8r2z/pdb 
WWPDB D_1292134494 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_database_PDB_caveat.id     1 
_database_PDB_caveat.text   'XR9 A 301 HAS WRONG CHIRALITY AT ATOM C4' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R2Z 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              jim.spencer@bristol.ac.uk 
_pdbx_contact_author.name_first         James 
_pdbx_contact_author.name_last          Spencer 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8611-4743 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Tooke, C.L.'    1 ? 
'Hinchliffe, P.' 2 ? 
'Spencer, J.'    3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of CTX-M-15 complexed with benzoxaborole AK-425' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Tooke, C.L.'    1 ? 
primary 'Hinchliffe, P.' 2 ? 
primary 'Spencer, J.'    3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Beta-lactamase                                                                    28292.990 1   3.5.2.6 ? ? ? 
2 non-polymer syn '(9S)-7-oxidanyl-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-triene-9-carbonitrile' 158.950   1   ?       ? ? ? 
3 non-polymer syn 'DIMETHYL SULFOXIDE'                                                              78.133    1   ?       ? ? ? 
4 non-polymer syn 'SULFATE ION'                                                                     96.063    4   ?       ? ? ? 
5 non-polymer syn 'CHLORIDE ION'                                                                    35.453    1   ?       ? ? ? 
6 non-polymer syn 'SODIUM ION'                                                                      22.990    2   ?       ? ? ? 
7 water       nat water                                                                             18.015    265 ?       ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GPQTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLV
NYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSP
RAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYF
TQPQPKAESRRDVLASAAKIVTDGL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GPQTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLV
NYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSP
RAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYF
TQPQPKAESRRDVLASAAKIVTDGL
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '(9S)-7-oxidanyl-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-triene-9-carbonitrile' XR9 
3 'DIMETHYL SULFOXIDE'                                                              DMS 
4 'SULFATE ION'                                                                     SO4 
5 'CHLORIDE ION'                                                                    CL  
6 'SODIUM ION'                                                                      NA  
7 water                                                                             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLN n 
1 4   THR n 
1 5   ALA n 
1 6   ASP n 
1 7   VAL n 
1 8   GLN n 
1 9   GLN n 
1 10  LYS n 
1 11  LEU n 
1 12  ALA n 
1 13  GLU n 
1 14  LEU n 
1 15  GLU n 
1 16  ARG n 
1 17  GLN n 
1 18  SER n 
1 19  GLY n 
1 20  GLY n 
1 21  ARG n 
1 22  LEU n 
1 23  GLY n 
1 24  VAL n 
1 25  ALA n 
1 26  LEU n 
1 27  ILE n 
1 28  ASN n 
1 29  THR n 
1 30  ALA n 
1 31  ASP n 
1 32  ASN n 
1 33  SER n 
1 34  GLN n 
1 35  ILE n 
1 36  LEU n 
1 37  TYR n 
1 38  ARG n 
1 39  ALA n 
1 40  ASP n 
1 41  GLU n 
1 42  ARG n 
1 43  PHE n 
1 44  ALA n 
1 45  MET n 
1 46  CYS n 
1 47  SER n 
1 48  THR n 
1 49  SER n 
1 50  LYS n 
1 51  VAL n 
1 52  MET n 
1 53  ALA n 
1 54  ALA n 
1 55  ALA n 
1 56  ALA n 
1 57  VAL n 
1 58  LEU n 
1 59  LYS n 
1 60  LYS n 
1 61  SER n 
1 62  GLU n 
1 63  SER n 
1 64  GLU n 
1 65  PRO n 
1 66  ASN n 
1 67  LEU n 
1 68  LEU n 
1 69  ASN n 
1 70  GLN n 
1 71  ARG n 
1 72  VAL n 
1 73  GLU n 
1 74  ILE n 
1 75  LYS n 
1 76  LYS n 
1 77  SER n 
1 78  ASP n 
1 79  LEU n 
1 80  VAL n 
1 81  ASN n 
1 82  TYR n 
1 83  ASN n 
1 84  PRO n 
1 85  ILE n 
1 86  ALA n 
1 87  GLU n 
1 88  LYS n 
1 89  HIS n 
1 90  VAL n 
1 91  ASN n 
1 92  GLY n 
1 93  THR n 
1 94  MET n 
1 95  SER n 
1 96  LEU n 
1 97  ALA n 
1 98  GLU n 
1 99  LEU n 
1 100 SER n 
1 101 ALA n 
1 102 ALA n 
1 103 ALA n 
1 104 LEU n 
1 105 GLN n 
1 106 TYR n 
1 107 SER n 
1 108 ASP n 
1 109 ASN n 
1 110 VAL n 
1 111 ALA n 
1 112 MET n 
1 113 ASN n 
1 114 LYS n 
1 115 LEU n 
1 116 ILE n 
1 117 ALA n 
1 118 HIS n 
1 119 VAL n 
1 120 GLY n 
1 121 GLY n 
1 122 PRO n 
1 123 ALA n 
1 124 SER n 
1 125 VAL n 
1 126 THR n 
1 127 ALA n 
1 128 PHE n 
1 129 ALA n 
1 130 ARG n 
1 131 GLN n 
1 132 LEU n 
1 133 GLY n 
1 134 ASP n 
1 135 GLU n 
1 136 THR n 
1 137 PHE n 
1 138 ARG n 
1 139 LEU n 
1 140 ASP n 
1 141 ARG n 
1 142 THR n 
1 143 GLU n 
1 144 PRO n 
1 145 THR n 
1 146 LEU n 
1 147 ASN n 
1 148 THR n 
1 149 ALA n 
1 150 ILE n 
1 151 PRO n 
1 152 GLY n 
1 153 ASP n 
1 154 PRO n 
1 155 ARG n 
1 156 ASP n 
1 157 THR n 
1 158 THR n 
1 159 SER n 
1 160 PRO n 
1 161 ARG n 
1 162 ALA n 
1 163 MET n 
1 164 ALA n 
1 165 GLN n 
1 166 THR n 
1 167 LEU n 
1 168 ARG n 
1 169 ASN n 
1 170 LEU n 
1 171 THR n 
1 172 LEU n 
1 173 GLY n 
1 174 LYS n 
1 175 ALA n 
1 176 LEU n 
1 177 GLY n 
1 178 ASP n 
1 179 SER n 
1 180 GLN n 
1 181 ARG n 
1 182 ALA n 
1 183 GLN n 
1 184 LEU n 
1 185 VAL n 
1 186 THR n 
1 187 TRP n 
1 188 MET n 
1 189 LYS n 
1 190 GLY n 
1 191 ASN n 
1 192 THR n 
1 193 THR n 
1 194 GLY n 
1 195 ALA n 
1 196 ALA n 
1 197 SER n 
1 198 ILE n 
1 199 GLN n 
1 200 ALA n 
1 201 GLY n 
1 202 LEU n 
1 203 PRO n 
1 204 ALA n 
1 205 SER n 
1 206 TRP n 
1 207 VAL n 
1 208 VAL n 
1 209 GLY n 
1 210 ASP n 
1 211 LYS n 
1 212 THR n 
1 213 GLY n 
1 214 SER n 
1 215 GLY n 
1 216 GLY n 
1 217 TYR n 
1 218 GLY n 
1 219 THR n 
1 220 THR n 
1 221 ASN n 
1 222 ASP n 
1 223 ILE n 
1 224 ALA n 
1 225 VAL n 
1 226 ILE n 
1 227 TRP n 
1 228 PRO n 
1 229 LYS n 
1 230 ASP n 
1 231 ARG n 
1 232 ALA n 
1 233 PRO n 
1 234 LEU n 
1 235 ILE n 
1 236 LEU n 
1 237 VAL n 
1 238 THR n 
1 239 TYR n 
1 240 PHE n 
1 241 THR n 
1 242 GLN n 
1 243 PRO n 
1 244 GLN n 
1 245 PRO n 
1 246 LYS n 
1 247 ALA n 
1 248 GLU n 
1 249 SER n 
1 250 ARG n 
1 251 ARG n 
1 252 ASP n 
1 253 VAL n 
1 254 LEU n 
1 255 ALA n 
1 256 SER n 
1 257 ALA n 
1 258 ALA n 
1 259 LYS n 
1 260 ILE n 
1 261 VAL n 
1 262 THR n 
1 263 ASP n 
1 264 GLY n 
1 265 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   265 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 blaCTX-M-15 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Klebsiella pneumoniae' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     573 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              Solu 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                           ? 'C3 H7 N O2'      
89.093  
ARG 'L-peptide linking' y ARGININE                                                                          ? 'C6 H15 N4 O2 1'  
175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                        ? 'C4 H8 N2 O3'     
132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                   ? 'C4 H7 N O4'      
133.103 
CL  non-polymer         . 'CHLORIDE ION'                                                                    ? 'Cl -1'           
35.453  
CYS 'L-peptide linking' y CYSTEINE                                                                          ? 'C3 H7 N O2 S'    
121.158 
DMS non-polymer         . 'DIMETHYL SULFOXIDE'                                                              ? 'C2 H6 O S'       
78.133  
GLN 'L-peptide linking' y GLUTAMINE                                                                         ? 'C5 H10 N2 O3'    
146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                   ? 'C5 H9 N O4'      
147.129 
GLY 'peptide linking'   y GLYCINE                                                                           ? 'C2 H5 N O2'      
75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                         ? 'C6 H10 N3 O2 1'  
156.162 
HOH non-polymer         . WATER                                                                             ? 'H2 O'            
18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                                                        ? 'C6 H13 N O2'     
131.173 
LEU 'L-peptide linking' y LEUCINE                                                                           ? 'C6 H13 N O2'     
131.173 
LYS 'L-peptide linking' y LYSINE                                                                            ? 'C6 H15 N2 O2 1'  
147.195 
MET 'L-peptide linking' y METHIONINE                                                                        ? 'C5 H11 N O2 S'   
149.211 
NA  non-polymer         . 'SODIUM ION'                                                                      ? 'Na 1'            
22.990  
PHE 'L-peptide linking' y PHENYLALANINE                                                                     ? 'C9 H11 N O2'     
165.189 
PRO 'L-peptide linking' y PROLINE                                                                           ? 'C5 H9 N O2'      
115.130 
SER 'L-peptide linking' y SERINE                                                                            ? 'C3 H7 N O3'      
105.093 
SO4 non-polymer         . 'SULFATE ION'                                                                     ? 'O4 S -2'         
96.063  
THR 'L-peptide linking' y THREONINE                                                                         ? 'C4 H9 N O3'      
119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                        ? 'C11 H12 N2 O2'   
204.225 
TYR 'L-peptide linking' y TYROSINE                                                                          ? 'C9 H11 N O3'     
181.189 
VAL 'L-peptide linking' y VALINE                                                                            ? 'C5 H11 N O2'     
117.146 
XR9 non-polymer         . '(9S)-7-oxidanyl-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-triene-9-carbonitrile' ? 'C8 H6 B N O2 -1' 
158.950 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   24  ?   ?   ?   A . n 
A 1 2   PRO 2   25  ?   ?   ?   A . n 
A 1 3   GLN 3   26  ?   ?   ?   A . n 
A 1 4   THR 4   27  ?   ?   ?   A . n 
A 1 5   ALA 5   28  28  ALA ALA A . n 
A 1 6   ASP 6   29  29  ASP ASP A . n 
A 1 7   VAL 7   30  30  VAL VAL A . n 
A 1 8   GLN 8   31  31  GLN GLN A . n 
A 1 9   GLN 9   32  32  GLN GLN A . n 
A 1 10  LYS 10  33  33  LYS LYS A . n 
A 1 11  LEU 11  34  34  LEU LEU A . n 
A 1 12  ALA 12  35  35  ALA ALA A . n 
A 1 13  GLU 13  36  36  GLU GLU A . n 
A 1 14  LEU 14  37  37  LEU LEU A . n 
A 1 15  GLU 15  38  38  GLU GLU A . n 
A 1 16  ARG 16  39  39  ARG ARG A . n 
A 1 17  GLN 17  40  40  GLN GLN A . n 
A 1 18  SER 18  41  41  SER SER A . n 
A 1 19  GLY 19  42  42  GLY GLY A . n 
A 1 20  GLY 20  43  43  GLY GLY A . n 
A 1 21  ARG 21  44  44  ARG ARG A . n 
A 1 22  LEU 22  45  45  LEU LEU A . n 
A 1 23  GLY 23  46  46  GLY GLY A . n 
A 1 24  VAL 24  47  47  VAL VAL A . n 
A 1 25  ALA 25  48  48  ALA ALA A . n 
A 1 26  LEU 26  49  49  LEU LEU A . n 
A 1 27  ILE 27  50  50  ILE ILE A . n 
A 1 28  ASN 28  51  51  ASN ASN A . n 
A 1 29  THR 29  52  52  THR THR A . n 
A 1 30  ALA 30  53  53  ALA ALA A . n 
A 1 31  ASP 31  54  54  ASP ASP A . n 
A 1 32  ASN 32  55  55  ASN ASN A . n 
A 1 33  SER 33  56  56  SER SER A . n 
A 1 34  GLN 34  57  57  GLN GLN A . n 
A 1 35  ILE 35  58  58  ILE ILE A . n 
A 1 36  LEU 36  59  59  LEU LEU A . n 
A 1 37  TYR 37  60  60  TYR TYR A . n 
A 1 38  ARG 38  61  61  ARG ARG A . n 
A 1 39  ALA 39  62  62  ALA ALA A . n 
A 1 40  ASP 40  63  63  ASP ASP A . n 
A 1 41  GLU 41  64  64  GLU GLU A . n 
A 1 42  ARG 42  65  65  ARG ARG A . n 
A 1 43  PHE 43  66  66  PHE PHE A . n 
A 1 44  ALA 44  67  67  ALA ALA A . n 
A 1 45  MET 45  68  68  MET MET A . n 
A 1 46  CYS 46  69  69  CYS CYS A . n 
A 1 47  SER 47  70  70  SER SER A . n 
A 1 48  THR 48  71  71  THR THR A . n 
A 1 49  SER 49  72  72  SER SER A . n 
A 1 50  LYS 50  73  73  LYS LYS A . n 
A 1 51  VAL 51  74  74  VAL VAL A . n 
A 1 52  MET 52  75  75  MET MET A . n 
A 1 53  ALA 53  76  76  ALA ALA A . n 
A 1 54  ALA 54  77  77  ALA ALA A . n 
A 1 55  ALA 55  78  78  ALA ALA A . n 
A 1 56  ALA 56  79  79  ALA ALA A . n 
A 1 57  VAL 57  80  80  VAL VAL A . n 
A 1 58  LEU 58  81  81  LEU LEU A . n 
A 1 59  LYS 59  82  82  LYS LYS A . n 
A 1 60  LYS 60  83  83  LYS LYS A . n 
A 1 61  SER 61  84  84  SER SER A . n 
A 1 62  GLU 62  85  85  GLU GLU A . n 
A 1 63  SER 63  86  86  SER SER A . n 
A 1 64  GLU 64  87  87  GLU GLU A . n 
A 1 65  PRO 65  88  88  PRO PRO A . n 
A 1 66  ASN 66  89  89  ASN ASN A . n 
A 1 67  LEU 67  90  90  LEU LEU A . n 
A 1 68  LEU 68  91  91  LEU LEU A . n 
A 1 69  ASN 69  92  92  ASN ASN A . n 
A 1 70  GLN 70  93  93  GLN GLN A . n 
A 1 71  ARG 71  94  94  ARG ARG A . n 
A 1 72  VAL 72  95  95  VAL VAL A . n 
A 1 73  GLU 73  96  96  GLU GLU A . n 
A 1 74  ILE 74  97  97  ILE ILE A . n 
A 1 75  LYS 75  98  98  LYS LYS A . n 
A 1 76  LYS 76  99  99  LYS LYS A . n 
A 1 77  SER 77  100 100 SER SER A . n 
A 1 78  ASP 78  101 101 ASP ASP A . n 
A 1 79  LEU 79  102 102 LEU LEU A . n 
A 1 80  VAL 80  103 103 VAL VAL A . n 
A 1 81  ASN 81  104 104 ASN ASN A . n 
A 1 82  TYR 82  105 105 TYR TYR A . n 
A 1 83  ASN 83  106 106 ASN ASN A . n 
A 1 84  PRO 84  107 107 PRO PRO A . n 
A 1 85  ILE 85  108 108 ILE ILE A . n 
A 1 86  ALA 86  109 109 ALA ALA A . n 
A 1 87  GLU 87  110 110 GLU GLU A . n 
A 1 88  LYS 88  111 111 LYS LYS A . n 
A 1 89  HIS 89  112 112 HIS HIS A . n 
A 1 90  VAL 90  113 113 VAL VAL A . n 
A 1 91  ASN 91  114 114 ASN ASN A . n 
A 1 92  GLY 92  115 115 GLY GLY A . n 
A 1 93  THR 93  116 116 THR THR A . n 
A 1 94  MET 94  117 117 MET MET A . n 
A 1 95  SER 95  118 118 SER SER A . n 
A 1 96  LEU 96  119 119 LEU LEU A . n 
A 1 97  ALA 97  120 120 ALA ALA A . n 
A 1 98  GLU 98  121 121 GLU GLU A . n 
A 1 99  LEU 99  122 122 LEU LEU A . n 
A 1 100 SER 100 123 123 SER SER A . n 
A 1 101 ALA 101 124 124 ALA ALA A . n 
A 1 102 ALA 102 125 125 ALA ALA A . n 
A 1 103 ALA 103 126 126 ALA ALA A . n 
A 1 104 LEU 104 127 127 LEU LEU A . n 
A 1 105 GLN 105 128 128 GLN GLN A . n 
A 1 106 TYR 106 129 129 TYR TYR A . n 
A 1 107 SER 107 130 130 SER SER A . n 
A 1 108 ASP 108 131 131 ASP ASP A . n 
A 1 109 ASN 109 132 132 ASN ASN A . n 
A 1 110 VAL 110 133 133 VAL VAL A . n 
A 1 111 ALA 111 134 134 ALA ALA A . n 
A 1 112 MET 112 135 135 MET MET A . n 
A 1 113 ASN 113 136 136 ASN ASN A . n 
A 1 114 LYS 114 137 137 LYS LYS A . n 
A 1 115 LEU 115 138 138 LEU LEU A . n 
A 1 116 ILE 116 139 139 ILE ILE A . n 
A 1 117 ALA 117 140 140 ALA ALA A . n 
A 1 118 HIS 118 141 141 HIS HIS A . n 
A 1 119 VAL 119 142 142 VAL VAL A . n 
A 1 120 GLY 120 143 143 GLY GLY A . n 
A 1 121 GLY 121 144 144 GLY GLY A . n 
A 1 122 PRO 122 145 145 PRO PRO A . n 
A 1 123 ALA 123 146 146 ALA ALA A . n 
A 1 124 SER 124 147 147 SER SER A . n 
A 1 125 VAL 125 148 148 VAL VAL A . n 
A 1 126 THR 126 149 149 THR THR A . n 
A 1 127 ALA 127 150 150 ALA ALA A . n 
A 1 128 PHE 128 151 151 PHE PHE A . n 
A 1 129 ALA 129 152 152 ALA ALA A . n 
A 1 130 ARG 130 153 153 ARG ARG A . n 
A 1 131 GLN 131 154 154 GLN GLN A . n 
A 1 132 LEU 132 155 155 LEU LEU A . n 
A 1 133 GLY 133 156 156 GLY GLY A . n 
A 1 134 ASP 134 157 157 ASP ASP A . n 
A 1 135 GLU 135 158 158 GLU GLU A . n 
A 1 136 THR 136 159 159 THR THR A . n 
A 1 137 PHE 137 160 160 PHE PHE A . n 
A 1 138 ARG 138 161 161 ARG ARG A . n 
A 1 139 LEU 139 162 162 LEU LEU A . n 
A 1 140 ASP 140 163 163 ASP ASP A . n 
A 1 141 ARG 141 164 164 ARG ARG A . n 
A 1 142 THR 142 165 165 THR THR A . n 
A 1 143 GLU 143 166 166 GLU GLU A . n 
A 1 144 PRO 144 167 167 PRO PRO A . n 
A 1 145 THR 145 168 168 THR THR A . n 
A 1 146 LEU 146 169 169 LEU LEU A . n 
A 1 147 ASN 147 170 170 ASN ASN A . n 
A 1 148 THR 148 171 171 THR THR A . n 
A 1 149 ALA 149 172 172 ALA ALA A . n 
A 1 150 ILE 150 173 173 ILE ILE A . n 
A 1 151 PRO 151 174 174 PRO PRO A . n 
A 1 152 GLY 152 175 175 GLY GLY A . n 
A 1 153 ASP 153 176 176 ASP ASP A . n 
A 1 154 PRO 154 177 177 PRO PRO A . n 
A 1 155 ARG 155 178 178 ARG ARG A . n 
A 1 156 ASP 156 179 179 ASP ASP A . n 
A 1 157 THR 157 180 180 THR THR A . n 
A 1 158 THR 158 181 181 THR THR A . n 
A 1 159 SER 159 182 182 SER SER A . n 
A 1 160 PRO 160 183 183 PRO PRO A . n 
A 1 161 ARG 161 184 184 ARG ARG A . n 
A 1 162 ALA 162 185 185 ALA ALA A . n 
A 1 163 MET 163 186 186 MET MET A . n 
A 1 164 ALA 164 187 187 ALA ALA A . n 
A 1 165 GLN 165 188 188 GLN GLN A . n 
A 1 166 THR 166 189 189 THR THR A . n 
A 1 167 LEU 167 190 190 LEU LEU A . n 
A 1 168 ARG 168 191 191 ARG ARG A . n 
A 1 169 ASN 169 192 192 ASN ASN A . n 
A 1 170 LEU 170 193 193 LEU LEU A . n 
A 1 171 THR 171 194 194 THR THR A . n 
A 1 172 LEU 172 195 195 LEU LEU A . n 
A 1 173 GLY 173 196 196 GLY GLY A . n 
A 1 174 LYS 174 197 197 LYS LYS A . n 
A 1 175 ALA 175 198 198 ALA ALA A . n 
A 1 176 LEU 176 199 199 LEU LEU A . n 
A 1 177 GLY 177 200 200 GLY GLY A . n 
A 1 178 ASP 178 201 201 ASP ASP A . n 
A 1 179 SER 179 202 202 SER SER A . n 
A 1 180 GLN 180 203 203 GLN GLN A . n 
A 1 181 ARG 181 204 204 ARG ARG A . n 
A 1 182 ALA 182 205 205 ALA ALA A . n 
A 1 183 GLN 183 206 206 GLN GLN A . n 
A 1 184 LEU 184 207 207 LEU LEU A . n 
A 1 185 VAL 185 208 208 VAL VAL A . n 
A 1 186 THR 186 209 209 THR THR A . n 
A 1 187 TRP 187 210 210 TRP TRP A . n 
A 1 188 MET 188 211 211 MET MET A . n 
A 1 189 LYS 189 212 212 LYS LYS A . n 
A 1 190 GLY 190 213 213 GLY GLY A . n 
A 1 191 ASN 191 214 214 ASN ASN A . n 
A 1 192 THR 192 215 215 THR THR A . n 
A 1 193 THR 193 216 216 THR THR A . n 
A 1 194 GLY 194 217 217 GLY GLY A . n 
A 1 195 ALA 195 218 218 ALA ALA A . n 
A 1 196 ALA 196 219 219 ALA ALA A . n 
A 1 197 SER 197 220 220 SER SER A . n 
A 1 198 ILE 198 221 221 ILE ILE A . n 
A 1 199 GLN 199 222 222 GLN GLN A . n 
A 1 200 ALA 200 223 223 ALA ALA A . n 
A 1 201 GLY 201 224 224 GLY GLY A . n 
A 1 202 LEU 202 225 225 LEU LEU A . n 
A 1 203 PRO 203 226 226 PRO PRO A . n 
A 1 204 ALA 204 227 227 ALA ALA A . n 
A 1 205 SER 205 228 228 SER SER A . n 
A 1 206 TRP 206 229 229 TRP TRP A . n 
A 1 207 VAL 207 230 230 VAL VAL A . n 
A 1 208 VAL 208 231 231 VAL VAL A . n 
A 1 209 GLY 209 232 232 GLY GLY A . n 
A 1 210 ASP 210 233 233 ASP ASP A . n 
A 1 211 LYS 211 234 234 LYS LYS A . n 
A 1 212 THR 212 235 235 THR THR A . n 
A 1 213 GLY 213 236 236 GLY GLY A . n 
A 1 214 SER 214 237 237 SER SER A . n 
A 1 215 GLY 215 238 238 GLY GLY A . n 
A 1 216 GLY 216 239 239 GLY GLY A . n 
A 1 217 TYR 217 240 240 TYR TYR A . n 
A 1 218 GLY 218 241 241 GLY GLY A . n 
A 1 219 THR 219 242 242 THR THR A . n 
A 1 220 THR 220 243 243 THR THR A . n 
A 1 221 ASN 221 244 244 ASN ASN A . n 
A 1 222 ASP 222 245 245 ASP ASP A . n 
A 1 223 ILE 223 246 246 ILE ILE A . n 
A 1 224 ALA 224 247 247 ALA ALA A . n 
A 1 225 VAL 225 248 248 VAL VAL A . n 
A 1 226 ILE 226 249 249 ILE ILE A . n 
A 1 227 TRP 227 250 250 TRP TRP A . n 
A 1 228 PRO 228 251 251 PRO PRO A . n 
A 1 229 LYS 229 252 252 LYS LYS A . n 
A 1 230 ASP 230 253 253 ASP ASP A . n 
A 1 231 ARG 231 254 254 ARG ARG A . n 
A 1 232 ALA 232 255 255 ALA ALA A . n 
A 1 233 PRO 233 256 256 PRO PRO A . n 
A 1 234 LEU 234 257 257 LEU LEU A . n 
A 1 235 ILE 235 258 258 ILE ILE A . n 
A 1 236 LEU 236 259 259 LEU LEU A . n 
A 1 237 VAL 237 260 260 VAL VAL A . n 
A 1 238 THR 238 261 261 THR THR A . n 
A 1 239 TYR 239 262 262 TYR TYR A . n 
A 1 240 PHE 240 263 263 PHE PHE A . n 
A 1 241 THR 241 264 264 THR THR A . n 
A 1 242 GLN 242 265 265 GLN GLN A . n 
A 1 243 PRO 243 266 266 PRO PRO A . n 
A 1 244 GLN 244 267 267 GLN GLN A . n 
A 1 245 PRO 245 268 268 PRO PRO A . n 
A 1 246 LYS 246 269 269 LYS LYS A . n 
A 1 247 ALA 247 270 270 ALA ALA A . n 
A 1 248 GLU 248 271 271 GLU GLU A . n 
A 1 249 SER 249 272 272 SER SER A . n 
A 1 250 ARG 250 273 273 ARG ARG A . n 
A 1 251 ARG 251 274 274 ARG ARG A . n 
A 1 252 ASP 252 275 275 ASP ASP A . n 
A 1 253 VAL 253 276 276 VAL VAL A . n 
A 1 254 LEU 254 277 277 LEU LEU A . n 
A 1 255 ALA 255 278 278 ALA ALA A . n 
A 1 256 SER 256 279 279 SER SER A . n 
A 1 257 ALA 257 280 280 ALA ALA A . n 
A 1 258 ALA 258 281 281 ALA ALA A . n 
A 1 259 LYS 259 282 282 LYS LYS A . n 
A 1 260 ILE 260 283 283 ILE ILE A . n 
A 1 261 VAL 261 284 284 VAL VAL A . n 
A 1 262 THR 262 285 285 THR THR A . n 
A 1 263 ASP 263 286 286 ASP ASP A . n 
A 1 264 GLY 264 287 287 GLY GLY A . n 
A 1 265 LEU 265 288 288 LEU LEU A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        XR9 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   XR9 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 XR9 1   301 301 XR9 AK1 A . 
C 3 DMS 1   302 302 DMS DMS A . 
D 4 SO4 1   303 4   SO4 SO4 A . 
E 4 SO4 1   304 5   SO4 SO4 A . 
F 4 SO4 1   305 6   SO4 SO4 A . 
G 4 SO4 1   306 7   SO4 SO4 A . 
H 5 CL  1   307 1   CL  CL  A . 
I 6 NA  1   308 1   NA  NA  A . 
J 6 NA  1   309 2   NA  NA  A . 
K 7 HOH 1   401 179 HOH HOH A . 
K 7 HOH 2   402 47  HOH HOH A . 
K 7 HOH 3   403 243 HOH HOH A . 
K 7 HOH 4   404 99  HOH HOH A . 
K 7 HOH 5   405 224 HOH HOH A . 
K 7 HOH 6   406 235 HOH HOH A . 
K 7 HOH 7   407 119 HOH HOH A . 
K 7 HOH 8   408 240 HOH HOH A . 
K 7 HOH 9   409 157 HOH HOH A . 
K 7 HOH 10  410 146 HOH HOH A . 
K 7 HOH 11  411 259 HOH HOH A . 
K 7 HOH 12  412 108 HOH HOH A . 
K 7 HOH 13  413 185 HOH HOH A . 
K 7 HOH 14  414 213 HOH HOH A . 
K 7 HOH 15  415 212 HOH HOH A . 
K 7 HOH 16  416 140 HOH HOH A . 
K 7 HOH 17  417 222 HOH HOH A . 
K 7 HOH 18  418 36  HOH HOH A . 
K 7 HOH 19  419 138 HOH HOH A . 
K 7 HOH 20  420 217 HOH HOH A . 
K 7 HOH 21  421 168 HOH HOH A . 
K 7 HOH 22  422 71  HOH HOH A . 
K 7 HOH 23  423 127 HOH HOH A . 
K 7 HOH 24  424 178 HOH HOH A . 
K 7 HOH 25  425 29  HOH HOH A . 
K 7 HOH 26  426 93  HOH HOH A . 
K 7 HOH 27  427 86  HOH HOH A . 
K 7 HOH 28  428 200 HOH HOH A . 
K 7 HOH 29  429 75  HOH HOH A . 
K 7 HOH 30  430 16  HOH HOH A . 
K 7 HOH 31  431 61  HOH HOH A . 
K 7 HOH 32  432 11  HOH HOH A . 
K 7 HOH 33  433 23  HOH HOH A . 
K 7 HOH 34  434 124 HOH HOH A . 
K 7 HOH 35  435 12  HOH HOH A . 
K 7 HOH 36  436 128 HOH HOH A . 
K 7 HOH 37  437 161 HOH HOH A . 
K 7 HOH 38  438 3   HOH HOH A . 
K 7 HOH 39  439 216 HOH HOH A . 
K 7 HOH 40  440 183 HOH HOH A . 
K 7 HOH 41  441 60  HOH HOH A . 
K 7 HOH 42  442 117 HOH HOH A . 
K 7 HOH 43  443 14  HOH HOH A . 
K 7 HOH 44  444 6   HOH HOH A . 
K 7 HOH 45  445 134 HOH HOH A . 
K 7 HOH 46  446 242 HOH HOH A . 
K 7 HOH 47  447 133 HOH HOH A . 
K 7 HOH 48  448 53  HOH HOH A . 
K 7 HOH 49  449 144 HOH HOH A . 
K 7 HOH 50  450 21  HOH HOH A . 
K 7 HOH 51  451 4   HOH HOH A . 
K 7 HOH 52  452 219 HOH HOH A . 
K 7 HOH 53  453 210 HOH HOH A . 
K 7 HOH 54  454 82  HOH HOH A . 
K 7 HOH 55  455 10  HOH HOH A . 
K 7 HOH 56  456 15  HOH HOH A . 
K 7 HOH 57  457 22  HOH HOH A . 
K 7 HOH 58  458 67  HOH HOH A . 
K 7 HOH 59  459 70  HOH HOH A . 
K 7 HOH 60  460 32  HOH HOH A . 
K 7 HOH 61  461 136 HOH HOH A . 
K 7 HOH 62  462 84  HOH HOH A . 
K 7 HOH 63  463 34  HOH HOH A . 
K 7 HOH 64  464 20  HOH HOH A . 
K 7 HOH 65  465 227 HOH HOH A . 
K 7 HOH 66  466 7   HOH HOH A . 
K 7 HOH 67  467 64  HOH HOH A . 
K 7 HOH 68  468 130 HOH HOH A . 
K 7 HOH 69  469 145 HOH HOH A . 
K 7 HOH 70  470 43  HOH HOH A . 
K 7 HOH 71  471 106 HOH HOH A . 
K 7 HOH 72  472 175 HOH HOH A . 
K 7 HOH 73  473 81  HOH HOH A . 
K 7 HOH 74  474 249 HOH HOH A . 
K 7 HOH 75  475 13  HOH HOH A . 
K 7 HOH 76  476 9   HOH HOH A . 
K 7 HOH 77  477 39  HOH HOH A . 
K 7 HOH 78  478 5   HOH HOH A . 
K 7 HOH 79  479 54  HOH HOH A . 
K 7 HOH 80  480 33  HOH HOH A . 
K 7 HOH 81  481 25  HOH HOH A . 
K 7 HOH 82  482 165 HOH HOH A . 
K 7 HOH 83  483 52  HOH HOH A . 
K 7 HOH 84  484 41  HOH HOH A . 
K 7 HOH 85  485 59  HOH HOH A . 
K 7 HOH 86  486 8   HOH HOH A . 
K 7 HOH 87  487 172 HOH HOH A . 
K 7 HOH 88  488 122 HOH HOH A . 
K 7 HOH 89  489 148 HOH HOH A . 
K 7 HOH 90  490 120 HOH HOH A . 
K 7 HOH 91  491 226 HOH HOH A . 
K 7 HOH 92  492 112 HOH HOH A . 
K 7 HOH 93  493 74  HOH HOH A . 
K 7 HOH 94  494 26  HOH HOH A . 
K 7 HOH 95  495 2   HOH HOH A . 
K 7 HOH 96  496 80  HOH HOH A . 
K 7 HOH 97  497 17  HOH HOH A . 
K 7 HOH 98  498 223 HOH HOH A . 
K 7 HOH 99  499 206 HOH HOH A . 
K 7 HOH 100 500 230 HOH HOH A . 
K 7 HOH 101 501 40  HOH HOH A . 
K 7 HOH 102 502 50  HOH HOH A . 
K 7 HOH 103 503 97  HOH HOH A . 
K 7 HOH 104 504 44  HOH HOH A . 
K 7 HOH 105 505 1   HOH HOH A . 
K 7 HOH 106 506 147 HOH HOH A . 
K 7 HOH 107 507 28  HOH HOH A . 
K 7 HOH 108 508 214 HOH HOH A . 
K 7 HOH 109 509 155 HOH HOH A . 
K 7 HOH 110 510 45  HOH HOH A . 
K 7 HOH 111 511 31  HOH HOH A . 
K 7 HOH 112 512 234 HOH HOH A . 
K 7 HOH 113 513 69  HOH HOH A . 
K 7 HOH 114 514 65  HOH HOH A . 
K 7 HOH 115 515 105 HOH HOH A . 
K 7 HOH 116 516 142 HOH HOH A . 
K 7 HOH 117 517 57  HOH HOH A . 
K 7 HOH 118 518 46  HOH HOH A . 
K 7 HOH 119 519 77  HOH HOH A . 
K 7 HOH 120 520 103 HOH HOH A . 
K 7 HOH 121 521 159 HOH HOH A . 
K 7 HOH 122 522 263 HOH HOH A . 
K 7 HOH 123 523 267 HOH HOH A . 
K 7 HOH 124 524 38  HOH HOH A . 
K 7 HOH 125 525 162 HOH HOH A . 
K 7 HOH 126 526 111 HOH HOH A . 
K 7 HOH 127 527 88  HOH HOH A . 
K 7 HOH 128 528 27  HOH HOH A . 
K 7 HOH 129 529 76  HOH HOH A . 
K 7 HOH 130 530 258 HOH HOH A . 
K 7 HOH 131 531 257 HOH HOH A . 
K 7 HOH 132 532 113 HOH HOH A . 
K 7 HOH 133 533 228 HOH HOH A . 
K 7 HOH 134 534 250 HOH HOH A . 
K 7 HOH 135 535 62  HOH HOH A . 
K 7 HOH 136 536 268 HOH HOH A . 
K 7 HOH 137 537 83  HOH HOH A . 
K 7 HOH 138 538 89  HOH HOH A . 
K 7 HOH 139 539 35  HOH HOH A . 
K 7 HOH 140 540 92  HOH HOH A . 
K 7 HOH 141 541 229 HOH HOH A . 
K 7 HOH 142 542 19  HOH HOH A . 
K 7 HOH 143 543 174 HOH HOH A . 
K 7 HOH 144 544 73  HOH HOH A . 
K 7 HOH 145 545 201 HOH HOH A . 
K 7 HOH 146 546 18  HOH HOH A . 
K 7 HOH 147 547 166 HOH HOH A . 
K 7 HOH 148 548 107 HOH HOH A . 
K 7 HOH 149 549 94  HOH HOH A . 
K 7 HOH 150 550 152 HOH HOH A . 
K 7 HOH 151 551 245 HOH HOH A . 
K 7 HOH 152 552 118 HOH HOH A . 
K 7 HOH 153 553 131 HOH HOH A . 
K 7 HOH 154 554 79  HOH HOH A . 
K 7 HOH 155 555 169 HOH HOH A . 
K 7 HOH 156 556 149 HOH HOH A . 
K 7 HOH 157 557 253 HOH HOH A . 
K 7 HOH 158 558 193 HOH HOH A . 
K 7 HOH 159 559 186 HOH HOH A . 
K 7 HOH 160 560 173 HOH HOH A . 
K 7 HOH 161 561 91  HOH HOH A . 
K 7 HOH 162 562 63  HOH HOH A . 
K 7 HOH 163 563 191 HOH HOH A . 
K 7 HOH 164 564 211 HOH HOH A . 
K 7 HOH 165 565 30  HOH HOH A . 
K 7 HOH 166 566 158 HOH HOH A . 
K 7 HOH 167 567 239 HOH HOH A . 
K 7 HOH 168 568 37  HOH HOH A . 
K 7 HOH 169 569 209 HOH HOH A . 
K 7 HOH 170 570 177 HOH HOH A . 
K 7 HOH 171 571 51  HOH HOH A . 
K 7 HOH 172 572 150 HOH HOH A . 
K 7 HOH 173 573 261 HOH HOH A . 
K 7 HOH 174 574 215 HOH HOH A . 
K 7 HOH 175 575 132 HOH HOH A . 
K 7 HOH 176 576 264 HOH HOH A . 
K 7 HOH 177 577 85  HOH HOH A . 
K 7 HOH 178 578 232 HOH HOH A . 
K 7 HOH 179 579 236 HOH HOH A . 
K 7 HOH 180 580 180 HOH HOH A . 
K 7 HOH 181 581 68  HOH HOH A . 
K 7 HOH 182 582 181 HOH HOH A . 
K 7 HOH 183 583 182 HOH HOH A . 
K 7 HOH 184 584 42  HOH HOH A . 
K 7 HOH 185 585 197 HOH HOH A . 
K 7 HOH 186 586 102 HOH HOH A . 
K 7 HOH 187 587 123 HOH HOH A . 
K 7 HOH 188 588 270 HOH HOH A . 
K 7 HOH 189 589 221 HOH HOH A . 
K 7 HOH 190 590 269 HOH HOH A . 
K 7 HOH 191 591 135 HOH HOH A . 
K 7 HOH 192 592 231 HOH HOH A . 
K 7 HOH 193 593 55  HOH HOH A . 
K 7 HOH 194 594 203 HOH HOH A . 
K 7 HOH 195 595 196 HOH HOH A . 
K 7 HOH 196 596 241 HOH HOH A . 
K 7 HOH 197 597 247 HOH HOH A . 
K 7 HOH 198 598 246 HOH HOH A . 
K 7 HOH 199 599 170 HOH HOH A . 
K 7 HOH 200 600 233 HOH HOH A . 
K 7 HOH 201 601 251 HOH HOH A . 
K 7 HOH 202 602 271 HOH HOH A . 
K 7 HOH 203 603 252 HOH HOH A . 
K 7 HOH 204 604 72  HOH HOH A . 
K 7 HOH 205 605 238 HOH HOH A . 
K 7 HOH 206 606 115 HOH HOH A . 
K 7 HOH 207 607 163 HOH HOH A . 
K 7 HOH 208 608 192 HOH HOH A . 
K 7 HOH 209 609 194 HOH HOH A . 
K 7 HOH 210 610 255 HOH HOH A . 
K 7 HOH 211 611 256 HOH HOH A . 
K 7 HOH 212 612 198 HOH HOH A . 
K 7 HOH 213 613 225 HOH HOH A . 
K 7 HOH 214 614 199 HOH HOH A . 
K 7 HOH 215 615 129 HOH HOH A . 
K 7 HOH 216 616 114 HOH HOH A . 
K 7 HOH 217 617 66  HOH HOH A . 
K 7 HOH 218 618 205 HOH HOH A . 
K 7 HOH 219 619 126 HOH HOH A . 
K 7 HOH 220 620 204 HOH HOH A . 
K 7 HOH 221 621 195 HOH HOH A . 
K 7 HOH 222 622 218 HOH HOH A . 
K 7 HOH 223 623 220 HOH HOH A . 
K 7 HOH 224 624 237 HOH HOH A . 
K 7 HOH 225 625 266 HOH HOH A . 
K 7 HOH 226 626 262 HOH HOH A . 
K 7 HOH 227 627 244 HOH HOH A . 
K 7 HOH 228 628 151 HOH HOH A . 
K 7 HOH 229 629 109 HOH HOH A . 
K 7 HOH 230 630 48  HOH HOH A . 
K 7 HOH 231 631 207 HOH HOH A . 
K 7 HOH 232 632 78  HOH HOH A . 
K 7 HOH 233 633 100 HOH HOH A . 
K 7 HOH 234 634 154 HOH HOH A . 
K 7 HOH 235 635 143 HOH HOH A . 
K 7 HOH 236 636 189 HOH HOH A . 
K 7 HOH 237 637 125 HOH HOH A . 
K 7 HOH 238 638 248 HOH HOH A . 
K 7 HOH 239 639 167 HOH HOH A . 
K 7 HOH 240 640 171 HOH HOH A . 
K 7 HOH 241 641 110 HOH HOH A . 
K 7 HOH 242 642 49  HOH HOH A . 
K 7 HOH 243 643 187 HOH HOH A . 
K 7 HOH 244 644 96  HOH HOH A . 
K 7 HOH 245 645 164 HOH HOH A . 
K 7 HOH 246 646 116 HOH HOH A . 
K 7 HOH 247 647 98  HOH HOH A . 
K 7 HOH 248 648 95  HOH HOH A . 
K 7 HOH 249 649 254 HOH HOH A . 
K 7 HOH 250 650 160 HOH HOH A . 
K 7 HOH 251 651 208 HOH HOH A . 
K 7 HOH 252 652 137 HOH HOH A . 
K 7 HOH 253 653 141 HOH HOH A . 
K 7 HOH 254 654 153 HOH HOH A . 
K 7 HOH 255 655 265 HOH HOH A . 
K 7 HOH 256 656 87  HOH HOH A . 
K 7 HOH 257 657 202 HOH HOH A . 
K 7 HOH 258 658 184 HOH HOH A . 
K 7 HOH 259 659 188 HOH HOH A . 
K 7 HOH 260 660 139 HOH HOH A . 
K 7 HOH 261 661 190 HOH HOH A . 
K 7 HOH 262 662 90  HOH HOH A . 
K 7 HOH 263 663 260 HOH HOH A . 
K 7 HOH 264 664 176 HOH HOH A . 
K 7 HOH 265 665 156 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20.1_4487 1 
? 'model building' ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20.1_4487 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .           3 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R2Z 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     44.438 
_cell.length_a_esd                 ? 
_cell.length_b                     45.514 
_cell.length_b_esd                 ? 
_cell.length_c                     116.923 
_cell.length_c_esd                 ? 
_cell.volume                       236482.746 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R2Z 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R2Z 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.09 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          41.14 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '2.0 M ammonium sulphate, 0.1 M Tris 8.0' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            292.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-07-16 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.6741 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.6741 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          11.67 
_reflns.entry_id                                       8R2Z 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.098 
_reflns.d_resolution_low                               58.461 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     97267 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.7 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                12.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.043 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.098 
_reflns_shell.d_res_low                                     1.117 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.6 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4763 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               12.4 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               1.162 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.337 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.2 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               18.67 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8R2Z 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.10 
_refine.ls_d_res_low                             41.54 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     97052 
_refine.ls_number_reflns_R_free                  4807 
_refine.ls_number_reflns_R_work                  92245 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.52 
_refine.ls_percent_reflns_R_free                 4.95 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1412 
_refine.ls_R_factor_R_free                       0.1677 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1398 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'FOURIER SYNTHESIS' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 17.0502 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1214 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.10 
_refine_hist.d_res_low                        41.54 
_refine_hist.number_atoms_solvent             265 
_refine_hist.number_atoms_total               2261 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1957 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         39 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0067  ? 2212 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0003  ? 3034 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0780  ? 340  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0109  ? 410  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 11.6839 ? 848  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.10 1.11  . . 145 2944 95.84  . . . . 0.3138 . . . . . . . . . . . 0.3528 
'X-RAY DIFFRACTION' 1.11 1.12  . . 142 2965 98.07  . . . . 0.2867 . . . . . . . . . . . 0.3117 
'X-RAY DIFFRACTION' 1.12 1.14  . . 171 3080 98.84  . . . . 0.2842 . . . . . . . . . . . 0.2872 
'X-RAY DIFFRACTION' 1.14 1.15  . . 150 2973 99.24  . . . . 0.2717 . . . . . . . . . . . 0.3087 
'X-RAY DIFFRACTION' 1.15 1.17  . . 175 3047 99.75  . . . . 0.2548 . . . . . . . . . . . 0.2784 
'X-RAY DIFFRACTION' 1.17 1.18  . . 147 3015 99.15  . . . . 0.2451 . . . . . . . . . . . 0.2899 
'X-RAY DIFFRACTION' 1.18 1.20  . . 160 3083 99.63  . . . . 0.2383 . . . . . . . . . . . 0.2480 
'X-RAY DIFFRACTION' 1.20 1.22  . . 171 3002 99.62  . . . . 0.2207 . . . . . . . . . . . 0.2192 
'X-RAY DIFFRACTION' 1.22 1.24  . . 155 3052 99.47  . . . . 0.2121 . . . . . . . . . . . 0.2449 
'X-RAY DIFFRACTION' 1.24 1.26  . . 175 3019 99.97  . . . . 0.2126 . . . . . . . . . . . 0.2294 
'X-RAY DIFFRACTION' 1.26 1.28  . . 147 3084 99.60  . . . . 0.2053 . . . . . . . . . . . 0.2623 
'X-RAY DIFFRACTION' 1.28 1.30  . . 123 3129 99.91  . . . . 0.1924 . . . . . . . . . . . 0.2315 
'X-RAY DIFFRACTION' 1.30 1.33  . . 146 3019 99.75  . . . . 0.1776 . . . . . . . . . . . 0.2255 
'X-RAY DIFFRACTION' 1.33 1.35  . . 164 3036 98.52  . . . . 0.1791 . . . . . . . . . . . 0.1858 
'X-RAY DIFFRACTION' 1.35 1.38  . . 171 3069 99.97  . . . . 0.1665 . . . . . . . . . . . 0.2126 
'X-RAY DIFFRACTION' 1.38 1.42  . . 161 3054 99.91  . . . . 0.1418 . . . . . . . . . . . 0.1610 
'X-RAY DIFFRACTION' 1.42 1.45  . . 147 3069 99.97  . . . . 0.1248 . . . . . . . . . . . 0.1831 
'X-RAY DIFFRACTION' 1.45 1.49  . . 165 3087 99.97  . . . . 0.1248 . . . . . . . . . . . 0.1568 
'X-RAY DIFFRACTION' 1.49 1.53  . . 161 3075 100.00 . . . . 0.1152 . . . . . . . . . . . 0.1522 
'X-RAY DIFFRACTION' 1.53 1.58  . . 152 3111 100.00 . . . . 0.1168 . . . . . . . . . . . 0.1530 
'X-RAY DIFFRACTION' 1.58 1.64  . . 180 3046 100.00 . . . . 0.1119 . . . . . . . . . . . 0.1442 
'X-RAY DIFFRACTION' 1.64 1.71  . . 144 3097 100.00 . . . . 0.1084 . . . . . . . . . . . 0.1380 
'X-RAY DIFFRACTION' 1.71 1.78  . . 181 3092 100.00 . . . . 0.1057 . . . . . . . . . . . 0.1452 
'X-RAY DIFFRACTION' 1.78 1.88  . . 159 3105 100.00 . . . . 0.1059 . . . . . . . . . . . 0.1433 
'X-RAY DIFFRACTION' 1.88 2.00  . . 163 3112 100.00 . . . . 0.1078 . . . . . . . . . . . 0.1307 
'X-RAY DIFFRACTION' 2.00 2.15  . . 136 3146 100.00 . . . . 0.1028 . . . . . . . . . . . 0.1286 
'X-RAY DIFFRACTION' 2.15 2.37  . . 182 3133 100.00 . . . . 0.1074 . . . . . . . . . . . 0.1297 
'X-RAY DIFFRACTION' 2.37 2.71  . . 173 3074 98.36  . . . . 0.1093 . . . . . . . . . . . 0.1434 
'X-RAY DIFFRACTION' 2.71 3.41  . . 181 3184 99.91  . . . . 0.1237 . . . . . . . . . . . 0.1432 
'X-RAY DIFFRACTION' 3.41 41.54 . . 180 3343 99.97  . . . . 0.1509 . . . . . . . . . . . 0.1794 
# 
_struct.entry_id                     8R2Z 
_struct.title                        'Structure of CTX-M-15 complexed with benzoxaborole AK-425' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R2Z 
_struct_keywords.text            'Inhibitor, beta-lactamase, SBL, antibiotic resistance, boronate, ANTIMICROBIAL PROTEIN' 
_struct_keywords.pdbx_keywords   'ANTIMICROBIAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 4 ? 
G N N 4 ? 
H N N 5 ? 
I N N 6 ? 
J N N 6 ? 
K N N 7 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    G3G192_KLEPN 
_struct_ref.pdbx_db_accession          G3G192 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;QTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLVNY
NPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRA
MAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ
PQPKAESRRDVLASAAKIVTDGL
;
_struct_ref.pdbx_align_begin           49 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8R2Z 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 3 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 265 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             G3G192 
_struct_ref_seq.db_align_beg                  49 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  311 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       26 
_struct_ref_seq.pdbx_auth_seq_align_end       288 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8R2Z GLY A 1 ? UNP G3G192 ? ? 'expression tag' 24 1 
1 8R2Z PRO A 2 ? UNP G3G192 ? ? 'expression tag' 25 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 940   ? 
1 MORE         -48   ? 
1 'SSA (A^2)'  10970 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 5   ? GLY A 19  ? ALA A 28  GLY A 42  1 ? 15 
HELX_P HELX_P2  AA2 CYS A 46  ? THR A 48  ? CYS A 69  THR A 71  5 ? 3  
HELX_P HELX_P3  AA3 SER A 49  ? GLU A 62  ? SER A 72  GLU A 85  1 ? 14 
HELX_P HELX_P4  AA4 ASN A 66  ? ASN A 69  ? ASN A 89  ASN A 92  5 ? 4  
HELX_P HELX_P5  AA5 LYS A 75  ? LEU A 79  ? LYS A 98  LEU A 102 5 ? 5  
HELX_P HELX_P6  AA6 ILE A 85  ? VAL A 90  ? ILE A 108 VAL A 113 5 ? 6  
HELX_P HELX_P7  AA7 LEU A 96  ? TYR A 106 ? LEU A 119 TYR A 129 1 ? 11 
HELX_P HELX_P8  AA8 ASP A 108 ? GLY A 120 ? ASP A 131 GLY A 143 1 ? 13 
HELX_P HELX_P9  AA9 GLY A 121 ? GLY A 133 ? GLY A 144 GLY A 156 1 ? 13 
HELX_P HELX_P10 AB1 PRO A 144 ? THR A 148 ? PRO A 167 THR A 171 5 ? 5  
HELX_P HELX_P11 AB2 SER A 159 ? LEU A 172 ? SER A 182 LEU A 195 1 ? 14 
HELX_P HELX_P12 AB3 GLY A 177 ? GLY A 190 ? GLY A 200 GLY A 213 1 ? 14 
HELX_P HELX_P13 AB4 SER A 197 ? LEU A 202 ? SER A 220 LEU A 225 5 ? 6  
HELX_P HELX_P14 AB5 ARG A 250 ? ASP A 263 ? ARG A 273 ASP A 286 1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale none ? A SER 47  OG  ? ? ? 1_555 B XR9 . B2 A ? A SER 70  A XR9 301 1_555 ? ? ? ? ? ? ? 1.441 ? ? 
covale2 covale none ? A SER 47  OG  ? ? ? 1_555 B XR9 . B2 B ? A SER 70  A XR9 301 1_555 ? ? ? ? ? ? ? 1.446 ? ? 
metalc1 metalc ?    ? A ASP 134 OD2 ? ? ? 1_555 I NA  . NA ? ? A ASP 157 A NA  308 1_555 ? ? ? ? ? ? ? 2.671 ? ? 
metalc2 metalc ?    ? A THR 158 OG1 ? ? ? 1_555 I NA  . NA ? ? A THR 181 A NA  308 1_555 ? ? ? ? ? ? ? 2.732 ? ? 
metalc3 metalc ?    ? A GLY 194 O   ? ? ? 1_555 J NA  . NA ? ? A GLY 217 A NA  309 1_555 ? ? ? ? ? ? ? 2.745 ? ? 
metalc4 metalc ?    ? A ASP 222 OD2 ? ? ? 1_555 J NA  . NA ? ? A ASP 245 A NA  309 1_555 ? ? ? ? ? ? ? 2.774 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OD2 ? A ASP 134 ? A ASP 157 ? 1_555 NA ? I NA . ? A NA 308 ? 1_555 OG1 ? A THR 158 ? A THR 181 ? 1_555 121.3 ? 
2 O   ? A GLY 194 ? A GLY 217 ? 1_555 NA ? J NA . ? A NA 309 ? 1_555 OD2 ? A ASP 222 ? A ASP 245 ? 1_555 107.2 ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 XR9 B . A SER A 47 ? XR9 A 301 ? 1_555 SER A 70 ? 1_555 B2 OG SER 1 XR9 None 'Covalent chemical modification' 
2 XR9 B . B SER A 47 ? XR9 A 301 ? 1_555 SER A 70 ? 1_555 B2 OG SER 1 XR9 None 'Covalent chemical modification' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLU 
_struct_mon_prot_cis.label_seq_id           143 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLU 
_struct_mon_prot_cis.auth_seq_id            166 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    144 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     167 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       8.74 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 33  ? TYR A 37  ? SER A 56  TYR A 60  
AA1 2 ARG A 21  ? ASN A 28  ? ARG A 44  ASN A 51  
AA1 3 LEU A 234 ? THR A 241 ? LEU A 257 THR A 264 
AA1 4 THR A 219 ? TRP A 227 ? THR A 242 TRP A 250 
AA1 5 VAL A 207 ? GLY A 215 ? VAL A 230 GLY A 238 
AA2 1 PHE A 43  ? ALA A 44  ? PHE A 66  ALA A 67  
AA2 2 THR A 157 ? THR A 158 ? THR A 180 THR A 181 
AA3 1 ARG A 71  ? GLU A 73  ? ARG A 94  GLU A 96  
AA3 2 THR A 93  ? SER A 95  ? THR A 116 SER A 118 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O SER A 33  ? O SER A 56  N ASN A 28  ? N ASN A 51  
AA1 2 3 N GLY A 23  ? N GLY A 46  O TYR A 239 ? O TYR A 262 
AA1 3 4 O LEU A 234 ? O LEU A 257 N ILE A 226 ? N ILE A 249 
AA1 4 5 O TRP A 227 ? O TRP A 250 N VAL A 207 ? N VAL A 230 
AA2 1 2 N PHE A 43  ? N PHE A 66  O THR A 158 ? O THR A 181 
AA3 1 2 N VAL A 72  ? N VAL A 95  O MET A 94  ? O MET A 117 
# 
_pdbx_entry_details.entry_id                   8R2Z 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 HH12 A ARG 204 ? B O   A HOH 407 ? ? 1.53 
2  1 HH21 A ARG 161 ? ? OD2 A ASP 163 ? B 1.54 
3  1 O2   A SO4 305 ? A O   A HOH 401 ? ? 1.92 
4  1 OE1  A GLU 110 ? ? O   A HOH 402 ? ? 1.93 
5  1 O3   A SO4 304 ? ? O   A HOH 403 ? ? 1.96 
6  1 O    A HOH 427 ? ? O   A HOH 509 ? ? 2.03 
7  1 O    A PRO 88  ? ? O   A HOH 404 ? ? 2.04 
8  1 OE2  A GLU 36  ? ? O   A HOH 405 ? ? 2.06 
9  1 O    A HOH 603 ? ? O   A HOH 611 ? ? 2.07 
10 1 O3   A SO4 304 ? ? O   A HOH 406 ? ? 2.08 
11 1 O    A HOH 593 ? ? O   A HOH 624 ? ? 2.16 
12 1 O2   A SO4 305 ? B O   A HOH 401 ? ? 2.17 
13 1 O    A HOH 591 ? ? O   A HOH 661 ? ? 2.17 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 O A HOH 511 ? ? 1_555 O A HOH 663 ? ? 3_555 2.04 
2 1 O A HOH 403 ? ? 1_555 O A HOH 436 ? ? 3_555 2.07 
3 1 O A HOH 559 ? ? 1_555 O A HOH 599 ? ? 3_545 2.16 
4 1 O A HOH 443 ? ? 1_555 O A HOH 497 ? ? 4_445 2.16 
5 1 O A HOH 564 ? ? 1_555 O A HOH 572 ? ? 3_545 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 CYS A 69  ? ? 50.72   -140.47 
2 1 VAL A 103 ? ? -122.67 -136.46 
3 1 SER A 220 ? ? -103.98 -123.86 
# 
_pdbx_validate_chiral.id              1 
_pdbx_validate_chiral.PDB_model_num   1 
_pdbx_validate_chiral.auth_atom_id    C4 
_pdbx_validate_chiral.label_alt_id    B 
_pdbx_validate_chiral.auth_asym_id    A 
_pdbx_validate_chiral.auth_comp_id    XR9 
_pdbx_validate_chiral.auth_seq_id     301 
_pdbx_validate_chiral.PDB_ins_code    ? 
_pdbx_validate_chiral.details         'WRONG HAND' 
_pdbx_validate_chiral.omega           . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      A 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       665 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   5.98 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLY 24 ? A GLY 1 
2 1 Y 1 A PRO 25 ? A PRO 2 
3 1 Y 1 A GLN 26 ? A GLN 3 
4 1 Y 1 A THR 27 ? A THR 4 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CL  CL   CL N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
DMS S    S  N N 89  
DMS O    O  N N 90  
DMS C1   C  N N 91  
DMS C2   C  N N 92  
DMS H11  H  N N 93  
DMS H12  H  N N 94  
DMS H13  H  N N 95  
DMS H21  H  N N 96  
DMS H22  H  N N 97  
DMS H23  H  N N 98  
GLN N    N  N N 99  
GLN CA   C  N S 100 
GLN C    C  N N 101 
GLN O    O  N N 102 
GLN CB   C  N N 103 
GLN CG   C  N N 104 
GLN CD   C  N N 105 
GLN OE1  O  N N 106 
GLN NE2  N  N N 107 
GLN OXT  O  N N 108 
GLN H    H  N N 109 
GLN H2   H  N N 110 
GLN HA   H  N N 111 
GLN HB2  H  N N 112 
GLN HB3  H  N N 113 
GLN HG2  H  N N 114 
GLN HG3  H  N N 115 
GLN HE21 H  N N 116 
GLN HE22 H  N N 117 
GLN HXT  H  N N 118 
GLU N    N  N N 119 
GLU CA   C  N S 120 
GLU C    C  N N 121 
GLU O    O  N N 122 
GLU CB   C  N N 123 
GLU CG   C  N N 124 
GLU CD   C  N N 125 
GLU OE1  O  N N 126 
GLU OE2  O  N N 127 
GLU OXT  O  N N 128 
GLU H    H  N N 129 
GLU H2   H  N N 130 
GLU HA   H  N N 131 
GLU HB2  H  N N 132 
GLU HB3  H  N N 133 
GLU HG2  H  N N 134 
GLU HG3  H  N N 135 
GLU HE2  H  N N 136 
GLU HXT  H  N N 137 
GLY N    N  N N 138 
GLY CA   C  N N 139 
GLY C    C  N N 140 
GLY O    O  N N 141 
GLY OXT  O  N N 142 
GLY H    H  N N 143 
GLY H2   H  N N 144 
GLY HA2  H  N N 145 
GLY HA3  H  N N 146 
GLY HXT  H  N N 147 
HIS N    N  N N 148 
HIS CA   C  N S 149 
HIS C    C  N N 150 
HIS O    O  N N 151 
HIS CB   C  N N 152 
HIS CG   C  Y N 153 
HIS ND1  N  Y N 154 
HIS CD2  C  Y N 155 
HIS CE1  C  Y N 156 
HIS NE2  N  Y N 157 
HIS OXT  O  N N 158 
HIS H    H  N N 159 
HIS H2   H  N N 160 
HIS HA   H  N N 161 
HIS HB2  H  N N 162 
HIS HB3  H  N N 163 
HIS HD1  H  N N 164 
HIS HD2  H  N N 165 
HIS HE1  H  N N 166 
HIS HE2  H  N N 167 
HIS HXT  H  N N 168 
HOH O    O  N N 169 
HOH H1   H  N N 170 
HOH H2   H  N N 171 
ILE N    N  N N 172 
ILE CA   C  N S 173 
ILE C    C  N N 174 
ILE O    O  N N 175 
ILE CB   C  N S 176 
ILE CG1  C  N N 177 
ILE CG2  C  N N 178 
ILE CD1  C  N N 179 
ILE OXT  O  N N 180 
ILE H    H  N N 181 
ILE H2   H  N N 182 
ILE HA   H  N N 183 
ILE HB   H  N N 184 
ILE HG12 H  N N 185 
ILE HG13 H  N N 186 
ILE HG21 H  N N 187 
ILE HG22 H  N N 188 
ILE HG23 H  N N 189 
ILE HD11 H  N N 190 
ILE HD12 H  N N 191 
ILE HD13 H  N N 192 
ILE HXT  H  N N 193 
LEU N    N  N N 194 
LEU CA   C  N S 195 
LEU C    C  N N 196 
LEU O    O  N N 197 
LEU CB   C  N N 198 
LEU CG   C  N N 199 
LEU CD1  C  N N 200 
LEU CD2  C  N N 201 
LEU OXT  O  N N 202 
LEU H    H  N N 203 
LEU H2   H  N N 204 
LEU HA   H  N N 205 
LEU HB2  H  N N 206 
LEU HB3  H  N N 207 
LEU HG   H  N N 208 
LEU HD11 H  N N 209 
LEU HD12 H  N N 210 
LEU HD13 H  N N 211 
LEU HD21 H  N N 212 
LEU HD22 H  N N 213 
LEU HD23 H  N N 214 
LEU HXT  H  N N 215 
LYS N    N  N N 216 
LYS CA   C  N S 217 
LYS C    C  N N 218 
LYS O    O  N N 219 
LYS CB   C  N N 220 
LYS CG   C  N N 221 
LYS CD   C  N N 222 
LYS CE   C  N N 223 
LYS NZ   N  N N 224 
LYS OXT  O  N N 225 
LYS H    H  N N 226 
LYS H2   H  N N 227 
LYS HA   H  N N 228 
LYS HB2  H  N N 229 
LYS HB3  H  N N 230 
LYS HG2  H  N N 231 
LYS HG3  H  N N 232 
LYS HD2  H  N N 233 
LYS HD3  H  N N 234 
LYS HE2  H  N N 235 
LYS HE3  H  N N 236 
LYS HZ1  H  N N 237 
LYS HZ2  H  N N 238 
LYS HZ3  H  N N 239 
LYS HXT  H  N N 240 
MET N    N  N N 241 
MET CA   C  N S 242 
MET C    C  N N 243 
MET O    O  N N 244 
MET CB   C  N N 245 
MET CG   C  N N 246 
MET SD   S  N N 247 
MET CE   C  N N 248 
MET OXT  O  N N 249 
MET H    H  N N 250 
MET H2   H  N N 251 
MET HA   H  N N 252 
MET HB2  H  N N 253 
MET HB3  H  N N 254 
MET HG2  H  N N 255 
MET HG3  H  N N 256 
MET HE1  H  N N 257 
MET HE2  H  N N 258 
MET HE3  H  N N 259 
MET HXT  H  N N 260 
NA  NA   NA N N 261 
PHE N    N  N N 262 
PHE CA   C  N S 263 
PHE C    C  N N 264 
PHE O    O  N N 265 
PHE CB   C  N N 266 
PHE CG   C  Y N 267 
PHE CD1  C  Y N 268 
PHE CD2  C  Y N 269 
PHE CE1  C  Y N 270 
PHE CE2  C  Y N 271 
PHE CZ   C  Y N 272 
PHE OXT  O  N N 273 
PHE H    H  N N 274 
PHE H2   H  N N 275 
PHE HA   H  N N 276 
PHE HB2  H  N N 277 
PHE HB3  H  N N 278 
PHE HD1  H  N N 279 
PHE HD2  H  N N 280 
PHE HE1  H  N N 281 
PHE HE2  H  N N 282 
PHE HZ   H  N N 283 
PHE HXT  H  N N 284 
PRO N    N  N N 285 
PRO CA   C  N S 286 
PRO C    C  N N 287 
PRO O    O  N N 288 
PRO CB   C  N N 289 
PRO CG   C  N N 290 
PRO CD   C  N N 291 
PRO OXT  O  N N 292 
PRO H    H  N N 293 
PRO HA   H  N N 294 
PRO HB2  H  N N 295 
PRO HB3  H  N N 296 
PRO HG2  H  N N 297 
PRO HG3  H  N N 298 
PRO HD2  H  N N 299 
PRO HD3  H  N N 300 
PRO HXT  H  N N 301 
SER N    N  N N 302 
SER CA   C  N S 303 
SER C    C  N N 304 
SER O    O  N N 305 
SER CB   C  N N 306 
SER OG   O  N N 307 
SER OXT  O  N N 308 
SER H    H  N N 309 
SER H2   H  N N 310 
SER HA   H  N N 311 
SER HB2  H  N N 312 
SER HB3  H  N N 313 
SER HG   H  N N 314 
SER HXT  H  N N 315 
SO4 S    S  N N 316 
SO4 O1   O  N N 317 
SO4 O2   O  N N 318 
SO4 O3   O  N N 319 
SO4 O4   O  N N 320 
THR N    N  N N 321 
THR CA   C  N S 322 
THR C    C  N N 323 
THR O    O  N N 324 
THR CB   C  N R 325 
THR OG1  O  N N 326 
THR CG2  C  N N 327 
THR OXT  O  N N 328 
THR H    H  N N 329 
THR H2   H  N N 330 
THR HA   H  N N 331 
THR HB   H  N N 332 
THR HG1  H  N N 333 
THR HG21 H  N N 334 
THR HG22 H  N N 335 
THR HG23 H  N N 336 
THR HXT  H  N N 337 
TRP N    N  N N 338 
TRP CA   C  N S 339 
TRP C    C  N N 340 
TRP O    O  N N 341 
TRP CB   C  N N 342 
TRP CG   C  Y N 343 
TRP CD1  C  Y N 344 
TRP CD2  C  Y N 345 
TRP NE1  N  Y N 346 
TRP CE2  C  Y N 347 
TRP CE3  C  Y N 348 
TRP CZ2  C  Y N 349 
TRP CZ3  C  Y N 350 
TRP CH2  C  Y N 351 
TRP OXT  O  N N 352 
TRP H    H  N N 353 
TRP H2   H  N N 354 
TRP HA   H  N N 355 
TRP HB2  H  N N 356 
TRP HB3  H  N N 357 
TRP HD1  H  N N 358 
TRP HE1  H  N N 359 
TRP HE3  H  N N 360 
TRP HZ2  H  N N 361 
TRP HZ3  H  N N 362 
TRP HH2  H  N N 363 
TRP HXT  H  N N 364 
TYR N    N  N N 365 
TYR CA   C  N S 366 
TYR C    C  N N 367 
TYR O    O  N N 368 
TYR CB   C  N N 369 
TYR CG   C  Y N 370 
TYR CD1  C  Y N 371 
TYR CD2  C  Y N 372 
TYR CE1  C  Y N 373 
TYR CE2  C  Y N 374 
TYR CZ   C  Y N 375 
TYR OH   O  N N 376 
TYR OXT  O  N N 377 
TYR H    H  N N 378 
TYR H2   H  N N 379 
TYR HA   H  N N 380 
TYR HB2  H  N N 381 
TYR HB3  H  N N 382 
TYR HD1  H  N N 383 
TYR HD2  H  N N 384 
TYR HE1  H  N N 385 
TYR HE2  H  N N 386 
TYR HH   H  N N 387 
TYR HXT  H  N N 388 
VAL N    N  N N 389 
VAL CA   C  N S 390 
VAL C    C  N N 391 
VAL O    O  N N 392 
VAL CB   C  N N 393 
VAL CG1  C  N N 394 
VAL CG2  C  N N 395 
VAL OXT  O  N N 396 
VAL H    H  N N 397 
VAL H2   H  N N 398 
VAL HA   H  N N 399 
VAL HB   H  N N 400 
VAL HG11 H  N N 401 
VAL HG12 H  N N 402 
VAL HG13 H  N N 403 
VAL HG21 H  N N 404 
VAL HG22 H  N N 405 
VAL HG23 H  N N 406 
VAL HXT  H  N N 407 
XR9 C12  C  Y N 408 
XR9 C11  C  Y N 409 
XR9 C9   C  Y N 410 
XR9 C7   C  Y N 411 
XR9 C4   C  N S 412 
XR9 N6   N  N N 413 
XR9 B2   B  N N 414 
XR9 C10  C  Y N 415 
XR9 C5   C  N N 416 
XR9 C8   C  Y N 417 
XR9 O1   O  N N 418 
XR9 O3   O  N N 419 
XR9 H11  H  N N 420 
XR9 H9   H  N N 421 
XR9 H4   H  N N 422 
XR9 H10  H  N N 423 
XR9 H8   H  N N 424 
XR9 H1   H  N N 425 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
DMS S   O    doub N N 83  
DMS S   C1   sing N N 84  
DMS S   C2   sing N N 85  
DMS C1  H11  sing N N 86  
DMS C1  H12  sing N N 87  
DMS C1  H13  sing N N 88  
DMS C2  H21  sing N N 89  
DMS C2  H22  sing N N 90  
DMS C2  H23  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
HIS N   CA   sing N N 138 
HIS N   H    sing N N 139 
HIS N   H2   sing N N 140 
HIS CA  C    sing N N 141 
HIS CA  CB   sing N N 142 
HIS CA  HA   sing N N 143 
HIS C   O    doub N N 144 
HIS C   OXT  sing N N 145 
HIS CB  CG   sing N N 146 
HIS CB  HB2  sing N N 147 
HIS CB  HB3  sing N N 148 
HIS CG  ND1  sing Y N 149 
HIS CG  CD2  doub Y N 150 
HIS ND1 CE1  doub Y N 151 
HIS ND1 HD1  sing N N 152 
HIS CD2 NE2  sing Y N 153 
HIS CD2 HD2  sing N N 154 
HIS CE1 NE2  sing Y N 155 
HIS CE1 HE1  sing N N 156 
HIS NE2 HE2  sing N N 157 
HIS OXT HXT  sing N N 158 
HOH O   H1   sing N N 159 
HOH O   H2   sing N N 160 
ILE N   CA   sing N N 161 
ILE N   H    sing N N 162 
ILE N   H2   sing N N 163 
ILE CA  C    sing N N 164 
ILE CA  CB   sing N N 165 
ILE CA  HA   sing N N 166 
ILE C   O    doub N N 167 
ILE C   OXT  sing N N 168 
ILE CB  CG1  sing N N 169 
ILE CB  CG2  sing N N 170 
ILE CB  HB   sing N N 171 
ILE CG1 CD1  sing N N 172 
ILE CG1 HG12 sing N N 173 
ILE CG1 HG13 sing N N 174 
ILE CG2 HG21 sing N N 175 
ILE CG2 HG22 sing N N 176 
ILE CG2 HG23 sing N N 177 
ILE CD1 HD11 sing N N 178 
ILE CD1 HD12 sing N N 179 
ILE CD1 HD13 sing N N 180 
ILE OXT HXT  sing N N 181 
LEU N   CA   sing N N 182 
LEU N   H    sing N N 183 
LEU N   H2   sing N N 184 
LEU CA  C    sing N N 185 
LEU CA  CB   sing N N 186 
LEU CA  HA   sing N N 187 
LEU C   O    doub N N 188 
LEU C   OXT  sing N N 189 
LEU CB  CG   sing N N 190 
LEU CB  HB2  sing N N 191 
LEU CB  HB3  sing N N 192 
LEU CG  CD1  sing N N 193 
LEU CG  CD2  sing N N 194 
LEU CG  HG   sing N N 195 
LEU CD1 HD11 sing N N 196 
LEU CD1 HD12 sing N N 197 
LEU CD1 HD13 sing N N 198 
LEU CD2 HD21 sing N N 199 
LEU CD2 HD22 sing N N 200 
LEU CD2 HD23 sing N N 201 
LEU OXT HXT  sing N N 202 
LYS N   CA   sing N N 203 
LYS N   H    sing N N 204 
LYS N   H2   sing N N 205 
LYS CA  C    sing N N 206 
LYS CA  CB   sing N N 207 
LYS CA  HA   sing N N 208 
LYS C   O    doub N N 209 
LYS C   OXT  sing N N 210 
LYS CB  CG   sing N N 211 
LYS CB  HB2  sing N N 212 
LYS CB  HB3  sing N N 213 
LYS CG  CD   sing N N 214 
LYS CG  HG2  sing N N 215 
LYS CG  HG3  sing N N 216 
LYS CD  CE   sing N N 217 
LYS CD  HD2  sing N N 218 
LYS CD  HD3  sing N N 219 
LYS CE  NZ   sing N N 220 
LYS CE  HE2  sing N N 221 
LYS CE  HE3  sing N N 222 
LYS NZ  HZ1  sing N N 223 
LYS NZ  HZ2  sing N N 224 
LYS NZ  HZ3  sing N N 225 
LYS OXT HXT  sing N N 226 
MET N   CA   sing N N 227 
MET N   H    sing N N 228 
MET N   H2   sing N N 229 
MET CA  C    sing N N 230 
MET CA  CB   sing N N 231 
MET CA  HA   sing N N 232 
MET C   O    doub N N 233 
MET C   OXT  sing N N 234 
MET CB  CG   sing N N 235 
MET CB  HB2  sing N N 236 
MET CB  HB3  sing N N 237 
MET CG  SD   sing N N 238 
MET CG  HG2  sing N N 239 
MET CG  HG3  sing N N 240 
MET SD  CE   sing N N 241 
MET CE  HE1  sing N N 242 
MET CE  HE2  sing N N 243 
MET CE  HE3  sing N N 244 
MET OXT HXT  sing N N 245 
PHE N   CA   sing N N 246 
PHE N   H    sing N N 247 
PHE N   H2   sing N N 248 
PHE CA  C    sing N N 249 
PHE CA  CB   sing N N 250 
PHE CA  HA   sing N N 251 
PHE C   O    doub N N 252 
PHE C   OXT  sing N N 253 
PHE CB  CG   sing N N 254 
PHE CB  HB2  sing N N 255 
PHE CB  HB3  sing N N 256 
PHE CG  CD1  doub Y N 257 
PHE CG  CD2  sing Y N 258 
PHE CD1 CE1  sing Y N 259 
PHE CD1 HD1  sing N N 260 
PHE CD2 CE2  doub Y N 261 
PHE CD2 HD2  sing N N 262 
PHE CE1 CZ   doub Y N 263 
PHE CE1 HE1  sing N N 264 
PHE CE2 CZ   sing Y N 265 
PHE CE2 HE2  sing N N 266 
PHE CZ  HZ   sing N N 267 
PHE OXT HXT  sing N N 268 
PRO N   CA   sing N N 269 
PRO N   CD   sing N N 270 
PRO N   H    sing N N 271 
PRO CA  C    sing N N 272 
PRO CA  CB   sing N N 273 
PRO CA  HA   sing N N 274 
PRO C   O    doub N N 275 
PRO C   OXT  sing N N 276 
PRO CB  CG   sing N N 277 
PRO CB  HB2  sing N N 278 
PRO CB  HB3  sing N N 279 
PRO CG  CD   sing N N 280 
PRO CG  HG2  sing N N 281 
PRO CG  HG3  sing N N 282 
PRO CD  HD2  sing N N 283 
PRO CD  HD3  sing N N 284 
PRO OXT HXT  sing N N 285 
SER N   CA   sing N N 286 
SER N   H    sing N N 287 
SER N   H2   sing N N 288 
SER CA  C    sing N N 289 
SER CA  CB   sing N N 290 
SER CA  HA   sing N N 291 
SER C   O    doub N N 292 
SER C   OXT  sing N N 293 
SER CB  OG   sing N N 294 
SER CB  HB2  sing N N 295 
SER CB  HB3  sing N N 296 
SER OG  HG   sing N N 297 
SER OXT HXT  sing N N 298 
SO4 S   O1   doub N N 299 
SO4 S   O2   doub N N 300 
SO4 S   O3   sing N N 301 
SO4 S   O4   sing N N 302 
THR N   CA   sing N N 303 
THR N   H    sing N N 304 
THR N   H2   sing N N 305 
THR CA  C    sing N N 306 
THR CA  CB   sing N N 307 
THR CA  HA   sing N N 308 
THR C   O    doub N N 309 
THR C   OXT  sing N N 310 
THR CB  OG1  sing N N 311 
THR CB  CG2  sing N N 312 
THR CB  HB   sing N N 313 
THR OG1 HG1  sing N N 314 
THR CG2 HG21 sing N N 315 
THR CG2 HG22 sing N N 316 
THR CG2 HG23 sing N N 317 
THR OXT HXT  sing N N 318 
TRP N   CA   sing N N 319 
TRP N   H    sing N N 320 
TRP N   H2   sing N N 321 
TRP CA  C    sing N N 322 
TRP CA  CB   sing N N 323 
TRP CA  HA   sing N N 324 
TRP C   O    doub N N 325 
TRP C   OXT  sing N N 326 
TRP CB  CG   sing N N 327 
TRP CB  HB2  sing N N 328 
TRP CB  HB3  sing N N 329 
TRP CG  CD1  doub Y N 330 
TRP CG  CD2  sing Y N 331 
TRP CD1 NE1  sing Y N 332 
TRP CD1 HD1  sing N N 333 
TRP CD2 CE2  doub Y N 334 
TRP CD2 CE3  sing Y N 335 
TRP NE1 CE2  sing Y N 336 
TRP NE1 HE1  sing N N 337 
TRP CE2 CZ2  sing Y N 338 
TRP CE3 CZ3  doub Y N 339 
TRP CE3 HE3  sing N N 340 
TRP CZ2 CH2  doub Y N 341 
TRP CZ2 HZ2  sing N N 342 
TRP CZ3 CH2  sing Y N 343 
TRP CZ3 HZ3  sing N N 344 
TRP CH2 HH2  sing N N 345 
TRP OXT HXT  sing N N 346 
TYR N   CA   sing N N 347 
TYR N   H    sing N N 348 
TYR N   H2   sing N N 349 
TYR CA  C    sing N N 350 
TYR CA  CB   sing N N 351 
TYR CA  HA   sing N N 352 
TYR C   O    doub N N 353 
TYR C   OXT  sing N N 354 
TYR CB  CG   sing N N 355 
TYR CB  HB2  sing N N 356 
TYR CB  HB3  sing N N 357 
TYR CG  CD1  doub Y N 358 
TYR CG  CD2  sing Y N 359 
TYR CD1 CE1  sing Y N 360 
TYR CD1 HD1  sing N N 361 
TYR CD2 CE2  doub Y N 362 
TYR CD2 HD2  sing N N 363 
TYR CE1 CZ   doub Y N 364 
TYR CE1 HE1  sing N N 365 
TYR CE2 CZ   sing Y N 366 
TYR CE2 HE2  sing N N 367 
TYR CZ  OH   sing N N 368 
TYR OH  HH   sing N N 369 
TYR OXT HXT  sing N N 370 
VAL N   CA   sing N N 371 
VAL N   H    sing N N 372 
VAL N   H2   sing N N 373 
VAL CA  C    sing N N 374 
VAL CA  CB   sing N N 375 
VAL CA  HA   sing N N 376 
VAL C   O    doub N N 377 
VAL C   OXT  sing N N 378 
VAL CB  CG1  sing N N 379 
VAL CB  CG2  sing N N 380 
VAL CB  HB   sing N N 381 
VAL CG1 HG11 sing N N 382 
VAL CG1 HG12 sing N N 383 
VAL CG1 HG13 sing N N 384 
VAL CG2 HG21 sing N N 385 
VAL CG2 HG22 sing N N 386 
VAL CG2 HG23 sing N N 387 
VAL OXT HXT  sing N N 388 
XR9 O1  B2   sing N N 389 
XR9 B2  O3   sing N N 390 
XR9 O3  C4   sing N N 391 
XR9 C4  C5   sing N N 392 
XR9 C5  N6   trip N N 393 
XR9 C4  C7   sing N N 394 
XR9 C7  C8   doub Y N 395 
XR9 C8  C9   sing Y N 396 
XR9 C9  C10  doub Y N 397 
XR9 C10 C11  sing Y N 398 
XR9 C11 C12  doub Y N 399 
XR9 C12 B2   sing N N 400 
XR9 C12 C7   sing Y N 401 
XR9 C11 H11  sing N N 402 
XR9 C9  H9   sing N N 403 
XR9 C4  H4   sing N N 404 
XR9 C10 H10  sing N N 405 
XR9 C8  H8   sing N N 406 
XR9 O1  H1   sing N N 407 
# 
_pdbx_audit_support.funding_organization   'Medical Research Council (MRC, United Kingdom)' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           MR/T016035/1 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6qw8 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8R2Z 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.022503 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.021971 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008553 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
B  ? ? 2.40390 1.74082 0.84097 ? 40.64930 0.64934  12.24639 ? 0.0 
;3-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
C  ? ? 3.54356 2.42580 ?       ? 25.62398 1.50364  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CL ? ? 9.50761 7.44341 ?       ? 1.04373  23.83732 ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345 0.48472 ?       ? 24.73122 6.32584  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032 2.96436 ?       ? 19.97189 1.75589  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
NA ? ? 6.63511 3.01293 1.30238 ? 5.54423  0.54580  90.85902 ? 0.0 
;3-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882 3.47563 ?       ? 15.80542 1.70748  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732 6.39887 ?       ? 1.23737  29.19336 ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . ALA A 1 5   ? 7.37236   -29.82953 6.19873  1.000 50.53897 ? 28  ALA A N    1 
ATOM   2    C  CA   . ALA A 1 5   ? 8.32066   -30.54751 5.35118  1.000 49.69948 ? 28  ALA A CA   1 
ATOM   3    C  C    . ALA A 1 5   ? 8.09117   -30.14920 3.89654  1.000 47.65274 ? 28  ALA A C    1 
ATOM   4    O  O    . ALA A 1 5   ? 8.70565   -29.20653 3.39525  1.000 46.74413 ? 28  ALA A O    1 
ATOM   5    C  CB   . ALA A 1 5   ? 8.15909   -32.03572 5.53808  1.000 50.39627 ? 28  ALA A CB   1 
ATOM   6    H  H    . ALA A 1 5   ? 7.46573   -29.97187 7.04094  1.000 60.64676 ? 28  ALA A H    1 
ATOM   7    H  HA   . ALA A 1 5   ? 9.23273   -30.32571 5.59578  1.000 59.63938 ? 28  ALA A HA   1 
ATOM   8    H  HB1  . ALA A 1 5   ? 8.56928   -32.49453 4.78832  1.000 60.47552 ? 28  ALA A HB1  1 
ATOM   9    H  HB2  . ALA A 1 5   ? 8.59304   -32.29915 6.36463  1.000 60.47552 ? 28  ALA A HB2  1 
ATOM   10   H  HB3  . ALA A 1 5   ? 7.21350   -32.24809 5.57865  1.000 60.47552 ? 28  ALA A HB3  1 
ATOM   11   N  N    . ASP A 1 6   ? 7.21244   -30.88189 3.21062  1.000 45.39543 ? 29  ASP A N    1 
ATOM   12   C  CA   . ASP A 1 6   ? 6.65819   -30.36377 1.96525  1.000 42.55956 ? 29  ASP A CA   1 
ATOM   13   C  C    . ASP A 1 6   ? 5.87172   -29.08698 2.23740  1.000 35.89342 ? 29  ASP A C    1 
ATOM   14   O  O    . ASP A 1 6   ? 5.92183   -28.13147 1.45387  1.000 34.23308 ? 29  ASP A O    1 
ATOM   15   C  CB   . ASP A 1 6   ? 5.76729   -31.41939 1.31832  1.000 47.03548 ? 29  ASP A CB   1 
ATOM   16   C  CG   . ASP A 1 6   ? 5.32278   -31.02997 -0.07530 1.000 51.12084 ? 29  ASP A CG   1 
ATOM   17   O  OD1  . ASP A 1 6   ? 6.19543   -30.77817 -0.93372 1.000 52.45611 ? 29  ASP A OD1  1 
ATOM   18   O  OD2  . ASP A 1 6   ? 4.09866   -30.98349 -0.31603 1.000 52.42910 ? 29  ASP A OD2  1 
ATOM   19   H  H    . ASP A 1 6   ? 6.92929   -31.66093 3.43977  1.000 54.47451 ? 29  ASP A H    1 
ATOM   20   H  HA   . ASP A 1 6   ? 7.37475   -30.16127 1.34361  1.000 51.07148 ? 29  ASP A HA   1 
ATOM   21   H  HB2  . ASP A 1 6   ? 6.25882   -32.25324 1.25515  1.000 56.44257 ? 29  ASP A HB2  1 
ATOM   22   H  HB3  . ASP A 1 6   ? 4.97445   -31.54213 1.86352  1.000 56.44257 ? 29  ASP A HB3  1 
ATOM   23   N  N    A VAL A 1 7   ? 5.14492   -29.05273 3.35528  0.446 33.65956 ? 30  VAL A N    1 
ATOM   24   N  N    B VAL A 1 7   ? 5.13839   -29.05139 3.35120  0.554 33.95113 ? 30  VAL A N    1 
ATOM   25   C  CA   A VAL A 1 7   ? 4.45109   -27.83319 3.75652  0.446 31.60555 ? 30  VAL A CA   1 
ATOM   26   C  CA   B VAL A 1 7   ? 4.45031   -27.82427 3.74178  0.554 32.23775 ? 30  VAL A CA   1 
ATOM   27   C  C    A VAL A 1 7   ? 5.44824   -26.69983 3.95907  0.446 30.84088 ? 30  VAL A C    1 
ATOM   28   C  C    B VAL A 1 7   ? 5.45494   -26.69706 3.94442  0.554 30.77594 ? 30  VAL A C    1 
ATOM   29   O  O    A VAL A 1 7   ? 5.16354   -25.53747 3.64836  0.446 29.48755 ? 30  VAL A O    1 
ATOM   30   O  O    B VAL A 1 7   ? 5.18212   -25.53577 3.62115  0.554 28.67557 ? 30  VAL A O    1 
ATOM   31   C  CB   A VAL A 1 7   ? 3.60543   -28.09926 5.01669  0.446 30.84156 ? 30  VAL A CB   1 
ATOM   32   C  CB   B VAL A 1 7   ? 3.59168   -28.06668 4.99695  0.554 32.63284 ? 30  VAL A CB   1 
ATOM   33   C  CG1  A VAL A 1 7   ? 4.48809   -28.55876 6.17235  0.446 30.12887 ? 30  VAL A CG1  1 
ATOM   34   C  CG1  B VAL A 1 7   ? 3.12684   -26.74822 5.58692  0.554 32.13872 ? 30  VAL A CG1  1 
ATOM   35   C  CG2  A VAL A 1 7   ? 2.81385   -26.86392 5.39976  0.446 30.46567 ? 30  VAL A CG2  1 
ATOM   36   C  CG2  B VAL A 1 7   ? 2.39078   -28.94812 4.66461  0.554 33.16784 ? 30  VAL A CG2  1 
ATOM   37   H  H    A VAL A 1 7   ? 5.03922   -29.71576 3.89270  0.446 40.39147 ? 30  VAL A H    1 
ATOM   38   H  H    B VAL A 1 7   ? 5.02557   -29.71334 3.88851  0.554 40.74136 ? 30  VAL A H    1 
ATOM   39   H  HA   A VAL A 1 7   ? 3.84649   -27.56456 3.04715  0.446 37.92666 ? 30  VAL A HA   1 
ATOM   40   H  HA   B VAL A 1 7   ? 3.85200   -27.56130 3.02500  0.554 38.68530 ? 30  VAL A HA   1 
ATOM   41   H  HB   A VAL A 1 7   ? 2.97482   -28.81046 4.82323  0.446 37.00988 ? 30  VAL A HB   1 
ATOM   42   H  HB   B VAL A 1 7   ? 4.13327   -28.52485 5.65851  0.554 39.15941 ? 30  VAL A HB   1 
ATOM   43   H  HG11 A VAL A 1 7   ? 3.94333   -28.64705 6.97006  0.446 36.15464 ? 30  VAL A HG11 1 
ATOM   44   H  HG11 B VAL A 1 7   ? 2.45578   -26.92467 6.26475  0.554 38.56647 ? 30  VAL A HG11 1 
ATOM   45   H  HG12 A VAL A 1 7   ? 4.88442   -29.41468 5.94606  0.446 36.15464 ? 30  VAL A HG12 1 
ATOM   46   H  HG12 B VAL A 1 7   ? 3.88672   -26.29452 5.98396  0.554 38.56647 ? 30  VAL A HG12 1 
ATOM   47   H  HG13 A VAL A 1 7   ? 5.18485   -27.90000 6.31886  0.446 36.15464 ? 30  VAL A HG13 1 
ATOM   48   H  HG13 B VAL A 1 7   ? 2.74778   -26.20227 4.88041  0.554 38.56647 ? 30  VAL A HG13 1 
ATOM   49   H  HG21 A VAL A 1 7   ? 2.28209   -27.06104 6.18670  0.446 36.55881 ? 30  VAL A HG21 1 
ATOM   50   H  HG21 B VAL A 1 7   ? 1.93458   -29.18371 5.48757  0.554 39.80141 ? 30  VAL A HG21 1 
ATOM   51   H  HG22 A VAL A 1 7   ? 3.43077   -26.14002 5.59024  0.446 36.55881 ? 30  VAL A HG22 1 
ATOM   52   H  HG22 B VAL A 1 7   ? 1.79014   -28.45709 4.08235  0.554 39.80141 ? 30  VAL A HG22 1 
ATOM   53   H  HG23 A VAL A 1 7   ? 2.23411   -26.61888 4.66168  0.446 36.55881 ? 30  VAL A HG23 1 
ATOM   54   H  HG23 B VAL A 1 7   ? 2.70218   -29.75068 4.21760  0.554 39.80141 ? 30  VAL A HG23 1 
ATOM   55   N  N    . GLN A 1 8   ? 6.63588   -27.02154 4.47617  1.000 31.48603 ? 31  GLN A N    1 
ATOM   56   C  CA   . GLN A 1 8   ? 7.66697   -26.00466 4.65475  1.000 32.76416 ? 31  GLN A CA   1 
ATOM   57   C  C    . GLN A 1 8   ? 8.10634   -25.42492 3.31936  1.000 32.40503 ? 31  GLN A C    1 
ATOM   58   O  O    . GLN A 1 8   ? 8.28024   -24.20754 3.18318  1.000 30.97364 ? 31  GLN A O    1 
ATOM   59   C  CB   . GLN A 1 8   ? 8.87261   -26.62748 5.35291  1.000 33.25132 ? 31  GLN A CB   1 
ATOM   60   C  CG   . GLN A 1 8   ? 8.60505   -27.00518 6.77936  1.000 35.04883 ? 31  GLN A CG   1 
ATOM   61   C  CD   . GLN A 1 8   ? 8.40300   -25.78385 7.62839  1.000 36.38389 ? 31  GLN A CD   1 
ATOM   62   O  OE1  . GLN A 1 8   ? 9.00960   -24.74485 7.37104  1.000 37.44591 ? 31  GLN A OE1  1 
ATOM   63   N  NE2  . GLN A 1 8   ? 7.54282   -25.88792 8.63257  1.000 36.12464 ? 31  GLN A NE2  1 
ATOM   64   H  H    A GLN A 1 8   ? 6.86541   -27.81120 4.72786  0.446 37.78323 ? 31  GLN A H    1 
ATOM   65   H  H    B GLN A 1 8   ? 6.85971   -27.80998 4.73670  0.554 37.78323 ? 31  GLN A H    1 
ATOM   66   H  HA   . GLN A 1 8   ? 7.30931   -25.28807 5.20199  1.000 39.31700 ? 31  GLN A HA   1 
ATOM   67   H  HB2  . GLN A 1 8   ? 9.13024   -27.43152 4.87536  1.000 39.90158 ? 31  GLN A HB2  1 
ATOM   68   H  HB3  . GLN A 1 8   ? 9.60289   -25.98910 5.34593  1.000 39.90158 ? 31  GLN A HB3  1 
ATOM   69   H  HG2  . GLN A 1 8   ? 7.80228   -27.54775 6.82483  1.000 42.05859 ? 31  GLN A HG2  1 
ATOM   70   H  HG3  . GLN A 1 8   ? 9.36128   -27.50161 7.12946  1.000 42.05859 ? 31  GLN A HG3  1 
ATOM   71   H  HE21 . GLN A 1 8   ? 7.13176   -26.63045 8.77145  1.000 43.34957 ? 31  GLN A HE21 1 
ATOM   72   H  HE22 . GLN A 1 8   ? 7.39612   -25.21287 9.14481  1.000 43.34957 ? 31  GLN A HE22 1 
ATOM   73   N  N    . GLN A 1 9   ? 8.32116   -26.28710 2.33039  1.000 32.74924 ? 32  GLN A N    1 
ATOM   74   C  CA   . GLN A 1 9   ? 8.69809   -25.81223 1.00773  1.000 33.60865 ? 32  GLN A CA   1 
ATOM   75   C  C    . GLN A 1 9   ? 7.59354   -24.95727 0.40683  1.000 29.75272 ? 32  GLN A C    1 
ATOM   76   O  O    . GLN A 1 9   ? 7.86586   -23.93662 -0.23628 1.000 27.54508 ? 32  GLN A O    1 
ATOM   77   C  CB   . GLN A 1 9   ? 9.00704   -27.01889 0.12489  1.000 38.86203 ? 32  GLN A CB   1 
ATOM   78   C  CG   . GLN A 1 9   ? 9.48214   -26.67510 -1.26004 1.000 44.96959 ? 32  GLN A CG   1 
ATOM   79   C  CD   . GLN A 1 9   ? 10.32100  -27.77915 -1.87325 1.000 49.30099 ? 32  GLN A CD   1 
ATOM   80   O  OE1  . GLN A 1 9   ? 10.73438  -28.71885 -1.19024 1.000 50.99402 ? 32  GLN A OE1  1 
ATOM   81   N  NE2  . GLN A 1 9   ? 10.58166  -27.66880 -3.16792 1.000 50.72165 ? 32  GLN A NE2  1 
ATOM   82   H  H    . GLN A 1 9   ? 8.25589   -27.14186 2.39906  1.000 39.29909 ? 32  GLN A H    1 
ATOM   83   H  HA   . GLN A 1 9   ? 9.49451   -25.26121 1.06226  1.000 40.33038 ? 32  GLN A HA   1 
ATOM   84   H  HB2  . GLN A 1 9   ? 9.70287   -27.54322 0.55128  1.000 46.63443 ? 32  GLN A HB2  1 
ATOM   85   H  HB3  . GLN A 1 9   ? 8.20021   -27.54964 0.03420  1.000 46.63443 ? 32  GLN A HB3  1 
ATOM   86   H  HG2  . GLN A 1 9   ? 8.71284   -26.52776 -1.83220 1.000 53.96351 ? 32  GLN A HG2  1 
ATOM   87   H  HG3  . GLN A 1 9   ? 10.02418  -25.87171 -1.21950 1.000 53.96351 ? 32  GLN A HG3  1 
ATOM   88   H  HE21 . GLN A 1 9   ? 10.27896  -26.99726 -3.61179 1.000 60.86599 ? 32  GLN A HE21 1 
ATOM   89   H  HE22 . GLN A 1 9   ? 11.05351  -28.26872 -3.56422 1.000 60.86599 ? 32  GLN A HE22 1 
ATOM   90   N  N    . LYS A 1 10  ? 6.33565   -25.34210 0.63148  1.000 26.58707 ? 33  LYS A N    1 
ATOM   91   C  CA   . LYS A 1 10  ? 5.22913   -24.57572 0.07402  1.000 24.57367 ? 33  LYS A CA   1 
ATOM   92   C  C    . LYS A 1 10  ? 5.13477   -23.19965 0.72193  1.000 20.81904 ? 33  LYS A C    1 
ATOM   93   O  O    . LYS A 1 10  ? 4.87892   -22.20161 0.03732  1.000 20.67778 ? 33  LYS A O    1 
ATOM   94   C  CB   . LYS A 1 10  ? 3.91795   -25.34305 0.24370  1.000 25.78036 ? 33  LYS A CB   1 
ATOM   95   C  CG   . LYS A 1 10  ? 3.80111   -26.54825 -0.68004 1.000 28.84149 ? 33  LYS A CG   1 
ATOM   96   C  CD   . LYS A 1 10  ? 2.48188   -27.27400 -0.47886 1.000 32.45714 ? 33  LYS A CD   1 
ATOM   97   C  CE   . LYS A 1 10  ? 2.29007   -28.34332 -1.54349 1.000 36.86364 ? 33  LYS A CE   1 
ATOM   98   N  NZ   . LYS A 1 10  ? 1.34025   -29.40062 -1.11424 1.000 39.49437 ? 33  LYS A NZ   1 
ATOM   99   H  H    . LYS A 1 10  ? 6.10344   -26.02904 1.09385  1.000 31.90448 ? 33  LYS A H    1 
ATOM   100  H  HA   . LYS A 1 10  ? 5.38014   -24.45256 -0.87621 1.000 29.48841 ? 33  LYS A HA   1 
ATOM   101  H  HB2  . LYS A 1 10  ? 3.85699   -25.66128 1.15799  1.000 30.93643 ? 33  LYS A HB2  1 
ATOM   102  H  HB3  . LYS A 1 10  ? 3.17815   -24.74631 0.05010  1.000 30.93643 ? 33  LYS A HB3  1 
ATOM   103  H  HG2  . LYS A 1 10  ? 3.84939   -26.25249 -1.60259 1.000 34.60979 ? 33  LYS A HG2  1 
ATOM   104  H  HG3  . LYS A 1 10  ? 4.52272   -27.16871 -0.49237 1.000 34.60979 ? 33  LYS A HG3  1 
ATOM   105  H  HD2  . LYS A 1 10  ? 2.47602   -27.70123 0.39196  1.000 38.94857 ? 33  LYS A HD2  1 
ATOM   106  H  HD3  . LYS A 1 10  ? 1.75002   -26.64058 -0.54257 1.000 38.94857 ? 33  LYS A HD3  1 
ATOM   107  H  HE2  . LYS A 1 10  ? 1.93942   -27.93142 -2.34864 1.000 44.23637 ? 33  LYS A HE2  1 
ATOM   108  H  HE3  . LYS A 1 10  ? 3.14437   -28.76295 -1.73053 1.000 44.23637 ? 33  LYS A HE3  1 
ATOM   109  H  HZ1  . LYS A 1 10  ? 0.56607   -29.03432 -0.87222 1.000 47.39325 ? 33  LYS A HZ1  1 
ATOM   110  H  HZ2  . LYS A 1 10  ? 1.19426   -29.96868 -1.78364 1.000 47.39325 ? 33  LYS A HZ2  1 
ATOM   111  H  HZ3  . LYS A 1 10  ? 1.67620   -29.84917 -0.42284 1.000 47.39325 ? 33  LYS A HZ3  1 
ATOM   112  N  N    . LEU A 1 11  ? 5.32091   -23.12457 2.04608  1.000 18.87761 ? 34  LEU A N    1 
ATOM   113  C  CA   . LEU A 1 11  ? 5.28403   -21.82589 2.70875  1.000 17.37034 ? 34  LEU A CA   1 
ATOM   114  C  C    . LEU A 1 11  ? 6.45095   -20.95529 2.24993  1.000 18.88539 ? 34  LEU A C    1 
ATOM   115  O  O    . LEU A 1 11  ? 6.29261   -19.74390 2.06173  1.000 17.28058 ? 34  LEU A O    1 
ATOM   116  C  CB   . LEU A 1 11  ? 5.29019   -21.99436 4.22909  1.000 17.63482 ? 34  LEU A CB   1 
ATOM   117  C  CG   . LEU A 1 11  ? 4.00483   -22.57264 4.81605  1.000 16.77905 ? 34  LEU A CG   1 
ATOM   118  C  CD1  . LEU A 1 11  ? 4.17257   -22.80194 6.30158  1.000 16.44741 ? 34  LEU A CD1  1 
ATOM   119  C  CD2  . LEU A 1 11  ? 2.81710   -21.65411 4.58130  1.000 15.34065 ? 34  LEU A CD2  1 
ATOM   120  H  H    . LEU A 1 11  ? 5.46603   -23.79446 2.56549  1.000 22.65313 ? 34  LEU A H    1 
ATOM   121  H  HA   . LEU A 1 11  ? 4.45645   -21.37677 2.47573  1.000 20.84440 ? 34  LEU A HA   1 
ATOM   122  H  HB2  . LEU A 1 11  ? 6.01550   -22.59222 4.46864  1.000 21.16178 ? 34  LEU A HB2  1 
ATOM   123  H  HB3  . LEU A 1 11  ? 5.43032   -21.12398 4.63370  1.000 21.16178 ? 34  LEU A HB3  1 
ATOM   124  H  HG   . LEU A 1 11  ? 3.82333   -23.41598 4.37251  1.000 20.13486 ? 34  LEU A HG   1 
ATOM   125  H  HD11 . LEU A 1 11  ? 3.35660   -23.18905 6.65549  1.000 19.73689 ? 34  LEU A HD11 1 
ATOM   126  H  HD12 . LEU A 1 11  ? 4.91589   -23.40827 6.44558  1.000 19.73689 ? 34  LEU A HD12 1 
ATOM   127  H  HD13 . LEU A 1 11  ? 4.35028   -21.95215 6.73421  1.000 19.73689 ? 34  LEU A HD13 1 
ATOM   128  H  HD21 . LEU A 1 11  ? 2.06243   -21.97507 5.09933  1.000 18.40878 ? 34  LEU A HD21 1 
ATOM   129  H  HD22 . LEU A 1 11  ? 3.05243   -20.75574 4.86137  1.000 18.40878 ? 34  LEU A HD22 1 
ATOM   130  H  HD23 . LEU A 1 11  ? 2.59599   -21.65890 3.63685  1.000 18.40878 ? 34  LEU A HD23 1 
ATOM   131  N  N    . ALA A 1 12  ? 7.62768   -21.55988 2.04593  1.000 20.10506 ? 35  ALA A N    1 
ATOM   132  C  CA   . ALA A 1 12  ? 8.76900   -20.79535 1.55704  1.000 20.76705 ? 35  ALA A CA   1 
ATOM   133  C  C    . ALA A 1 12  ? 8.49965   -20.24546 0.16200  1.000 21.30864 ? 35  ALA A C    1 
ATOM   134  O  O    . ALA A 1 12  ? 8.86473   -19.10401 -0.14469 1.000 21.17105 ? 35  ALA A O    1 
ATOM   135  C  CB   . ALA A 1 12  ? 10.02455  -21.66917 1.52910  1.000 22.30612 ? 35  ALA A CB   1 
ATOM   136  H  H    . ALA A 1 12  ? 7.78422   -22.39461 2.18129  1.000 24.12607 ? 35  ALA A H    1 
ATOM   137  H  HA   . ALA A 1 12  ? 8.92404   -20.05523 2.16456  1.000 24.92046 ? 35  ALA A HA   1 
ATOM   138  H  HB1  . ALA A 1 12  ? 10.78075  -21.12679 1.25544  1.000 26.76734 ? 35  ALA A HB1  1 
ATOM   139  H  HB2  . ALA A 1 12  ? 10.17913  -22.02838 2.41678  1.000 26.76734 ? 35  ALA A HB2  1 
ATOM   140  H  HB3  . ALA A 1 12  ? 9.89126   -22.39343 0.89777  1.000 26.76734 ? 35  ALA A HB3  1 
ATOM   141  N  N    . GLU A 1 13  ? 7.88416   -21.05532 -0.70691 1.000 21.55767 ? 36  GLU A N    1 
ATOM   142  C  CA   . GLU A 1 13  ? 7.52868   -20.57572 -2.03666 1.000 22.14774 ? 36  GLU A CA   1 
ATOM   143  C  C    . GLU A 1 13  ? 6.49370   -19.46591 -1.95893 1.000 19.87572 ? 36  GLU A C    1 
ATOM   144  O  O    . GLU A 1 13  ? 6.59019   -18.47090 -2.68630 1.000 20.39758 ? 36  GLU A O    1 
ATOM   145  C  CB   . GLU A 1 13  ? 7.02331   -21.73102 -2.89886 1.000 27.21244 ? 36  GLU A CB   1 
ATOM   146  C  CG   . GLU A 1 13  ? 6.46462   -21.31060 -4.25457 1.000 33.78215 ? 36  GLU A CG   1 
ATOM   147  C  CD   . GLU A 1 13  ? 7.50363   -20.68575 -5.17045 1.000 39.62126 ? 36  GLU A CD   1 
ATOM   148  O  OE1  . GLU A 1 13  ? 8.69740   -20.64833 -4.79628 1.000 40.46474 ? 36  GLU A OE1  1 
ATOM   149  O  OE2  . GLU A 1 13  ? 7.12148   -20.22904 -6.26648 1.000 41.89886 ? 36  GLU A OE2  1 
ATOM   150  H  H    . GLU A 1 13  ? 7.66659   -21.87244 -0.55017 1.000 25.86920 ? 36  GLU A H    1 
ATOM   151  H  HA   . GLU A 1 13  ? 8.32269   -20.21679 -2.46283 1.000 26.57729 ? 36  GLU A HA   1 
ATOM   152  H  HB2  . GLU A 1 13  ? 7.76024   -22.34036 -3.06177 1.000 32.65493 ? 36  GLU A HB2  1 
ATOM   153  H  HB3  . GLU A 1 13  ? 6.31495   -22.18792 -2.41889 1.000 32.65493 ? 36  GLU A HB3  1 
ATOM   154  H  HG2  . GLU A 1 13  ? 6.10659   -22.09314 -4.70218 1.000 40.53858 ? 36  GLU A HG2  1 
ATOM   155  H  HG3  . GLU A 1 13  ? 5.76116   -20.65756 -4.11464 1.000 40.53858 ? 36  GLU A HG3  1 
ATOM   156  N  N    . LEU A 1 14  ? 5.48990   -19.62477 -1.09701 1.000 18.57796 ? 37  LEU A N    1 
ATOM   157  C  CA   . LEU A 1 14  ? 4.50621   -18.56771 -0.92640 1.000 17.26402 ? 37  LEU A CA   1 
ATOM   158  C  C    . LEU A 1 14  ? 5.19144   -17.28647 -0.48151 1.000 16.57955 ? 37  LEU A C    1 
ATOM   159  O  O    . LEU A 1 14  ? 4.92156   -16.19911 -1.00886 1.000 16.45867 ? 37  LEU A O    1 
ATOM   160  C  CB   . LEU A 1 14  ? 3.45881   -18.98597 0.10885  1.000 16.46822 ? 37  LEU A CB   1 
ATOM   161  C  CG   . LEU A 1 14  ? 2.47325   -17.88947 0.51876  1.000 16.10205 ? 37  LEU A CG   1 
ATOM   162  C  CD1  . LEU A 1 14  ? 1.66838   -17.41176 -0.69444 1.000 17.25268 ? 37  LEU A CD1  1 
ATOM   163  C  CD2  . LEU A 1 14  ? 1.57023   -18.39279 1.62082  1.000 15.75843 ? 37  LEU A CD2  1 
ATOM   164  H  H    . LEU A 1 14  ? 5.36114   -20.32198 -0.61027 1.000 22.29355 ? 37  LEU A H    1 
ATOM   165  H  HA   . LEU A 1 14  ? 4.05339   -18.41372 -1.77029 1.000 20.71682 ? 37  LEU A HA   1 
ATOM   166  H  HB2  . LEU A 1 14  ? 2.94120   -19.71909 -0.25929 1.000 19.76186 ? 37  LEU A HB2  1 
ATOM   167  H  HB3  . LEU A 1 14  ? 3.92088   -19.27600 0.91089  1.000 19.76186 ? 37  LEU A HB3  1 
ATOM   168  H  HG   . LEU A 1 14  ? 2.95906   -17.12296 0.86134  1.000 19.32246 ? 37  LEU A HG   1 
ATOM   169  H  HD11 . LEU A 1 14  ? 0.97267   -16.80655 -0.39343 1.000 20.70321 ? 37  LEU A HD11 1 
ATOM   170  H  HD12 . LEU A 1 14  ? 2.26367   -16.95271 -1.30747 1.000 20.70321 ? 37  LEU A HD12 1 
ATOM   171  H  HD13 . LEU A 1 14  ? 1.27116   -18.18064 -1.13253 1.000 20.70321 ? 37  LEU A HD13 1 
ATOM   172  H  HD21 . LEU A 1 14  ? 0.93909   -17.69460 1.85554  1.000 18.91011 ? 37  LEU A HD21 1 
ATOM   173  H  HD22 . LEU A 1 14  ? 1.09402   -19.17683 1.30554  1.000 18.91011 ? 37  LEU A HD22 1 
ATOM   174  H  HD23 . LEU A 1 14  ? 2.11141   -18.62250 2.39235  1.000 18.91011 ? 37  LEU A HD23 1 
ATOM   175  N  N    . GLU A 1 15  ? 6.08653   -17.39409 0.50295  1.000 16.12742 ? 38  GLU A N    1 
ATOM   176  C  CA   . GLU A 1 15  ? 6.78494   -16.20943 0.97445  1.000 16.62972 ? 38  GLU A CA   1 
ATOM   177  C  C    . GLU A 1 15  ? 7.55880   -15.56426 -0.16580 1.000 18.23867 ? 38  GLU A C    1 
ATOM   178  O  O    . GLU A 1 15  ? 7.49233   -14.34652 -0.36770 1.000 17.73943 ? 38  GLU A O    1 
ATOM   179  C  CB   . GLU A 1 15  ? 7.72772   -16.56728 2.12056  1.000 15.90238 ? 38  GLU A CB   1 
ATOM   180  C  CG   . GLU A 1 15  ? 8.44124   -15.35070 2.64553  1.000 15.16951 ? 38  GLU A CG   1 
ATOM   181  C  CD   . GLU A 1 15  ? 9.33474   -15.66931 3.78995  1.000 14.68446 ? 38  GLU A CD   1 
ATOM   182  O  OE1  . GLU A 1 15  ? 10.25613  -16.49281 3.61149  1.000 15.77598 ? 38  GLU A OE1  1 
ATOM   183  O  OE2  . GLU A 1 15  ? 9.07106   -15.12288 4.87891  1.000 14.29120 ? 38  GLU A OE2  1 
ATOM   184  H  H    . GLU A 1 15  ? 6.29933   -18.12556 0.90203  1.000 19.35291 ? 38  GLU A H    1 
ATOM   185  H  HA   . GLU A 1 15  ? 6.13471   -15.57457 1.31366  1.000 19.95567 ? 38  GLU A HA   1 
ATOM   186  H  HB2  . GLU A 1 15  ? 7.21663   -16.95909 2.84593  1.000 19.08286 ? 38  GLU A HB2  1 
ATOM   187  H  HB3  . GLU A 1 15  ? 8.39228   -17.19897 1.80395  1.000 19.08286 ? 38  GLU A HB3  1 
ATOM   188  H  HG2  . GLU A 1 15  ? 8.98298   -14.96968 1.93685  1.000 18.20342 ? 38  GLU A HG2  1 
ATOM   189  H  HG3  . GLU A 1 15  ? 7.78508   -14.70276 2.94641  1.000 18.20342 ? 38  GLU A HG3  1 
ATOM   190  N  N    . ARG A 1 16  ? 8.30383   -16.38085 -0.92130 1.000 20.26105 ? 39  ARG A N    1 
ATOM   191  C  CA   . ARG A 1 16  ? 9.07004   -15.88086 -2.05822 1.000 22.19682 ? 39  ARG A CA   1 
ATOM   192  C  C    . ARG A 1 16  ? 8.17494   -15.12929 -3.03439 1.000 21.81466 ? 39  ARG A C    1 
ATOM   193  O  O    . ARG A 1 16  ? 8.48367   -13.99885 -3.43493 1.000 20.84399 ? 39  ARG A O    1 
ATOM   194  C  CB   . ARG A 1 16  ? 9.73225   -17.07753 -2.74898 1.000 27.10005 ? 39  ARG A CB   1 
ATOM   195  C  CG   . ARG A 1 16  ? 10.99580  -16.80679 -3.51338 1.000 34.47825 ? 39  ARG A CG   1 
ATOM   196  C  CD   . ARG A 1 16  ? 11.66625  -18.13980 -3.89191 1.000 39.08780 ? 39  ARG A CD   1 
ATOM   197  N  NE   . ARG A 1 16  ? 12.05368  -18.92649 -2.72264 1.000 42.47691 ? 39  ARG A NE   1 
ATOM   198  C  CZ   . ARG A 1 16  ? 11.60580  -20.14428 -2.43180 1.000 44.31444 ? 39  ARG A CZ   1 
ATOM   199  N  NH1  . ARG A 1 16  ? 10.77985  -20.79147 -3.23744 1.000 45.01072 ? 39  ARG A NH1  1 
ATOM   200  N  NH2  . ARG A 1 16  ? 12.00890  -20.73124 -1.30886 1.000 45.35498 ? 39  ARG A NH2  1 
ATOM   201  H  H    . ARG A 1 16  ? 8.38026   -17.22789 -0.79374 1.000 24.31327 ? 39  ARG A H    1 
ATOM   202  H  HA   . ARG A 1 16  ? 9.75317   -15.26356 -1.75295 1.000 26.63619 ? 39  ARG A HA   1 
ATOM   203  H  HB2  . ARG A 1 16  ? 9.94876   -17.73403 -2.06852 1.000 32.52007 ? 39  ARG A HB2  1 
ATOM   204  H  HB3  . ARG A 1 16  ? 9.09533   -17.45004 -3.37865 1.000 32.52007 ? 39  ARG A HB3  1 
ATOM   205  H  HG2  . ARG A 1 16  ? 10.78999  -16.31840 -4.32580 1.000 41.37390 ? 39  ARG A HG2  1 
ATOM   206  H  HG3  . ARG A 1 16  ? 11.60853  -16.29344 -2.96390 1.000 41.37390 ? 39  ARG A HG3  1 
ATOM   207  H  HD2  . ARG A 1 16  ? 11.04558  -18.66856 -4.41734 1.000 46.90536 ? 39  ARG A HD2  1 
ATOM   208  H  HD3  . ARG A 1 16  ? 12.46621  -17.95642 -4.40894 1.000 46.90536 ? 39  ARG A HD3  1 
ATOM   209  H  HE   . ARG A 1 16  ? 12.61756  -18.57279 -2.17809 1.000 50.97229 ? 39  ARG A HE   1 
ATOM   210  H  HH11 . ARG A 1 16  ? 10.51923  -20.42517 -3.97059 1.000 54.01286 ? 39  ARG A HH11 1 
ATOM   211  H  HH12 . ARG A 1 16  ? 10.50353  -21.57848 -3.02803 1.000 54.01286 ? 39  ARG A HH12 1 
ATOM   212  H  HH21 . ARG A 1 16  ? 12.55231  -20.32343 -0.78161 1.000 54.42598 ? 39  ARG A HH21 1 
ATOM   213  H  HH22 . ARG A 1 16  ? 11.72620  -21.51868 -1.10982 1.000 54.42598 ? 39  ARG A HH22 1 
ATOM   214  N  N    A GLN A 1 17  ? 7.06341   -15.75008 -3.43899 0.505 21.23637 ? 40  GLN A N    1 
ATOM   215  N  N    B GLN A 1 17  ? 7.05585   -15.74211 -3.43003 0.495 21.69650 ? 40  GLN A N    1 
ATOM   216  C  CA   A GLN A 1 17  ? 6.14424   -15.10269 -4.36368 0.505 22.02961 ? 40  GLN A CA   1 
ATOM   217  C  CA   B GLN A 1 17  ? 6.15222   -15.10041 -4.37566 0.495 22.90808 ? 40  GLN A CA   1 
ATOM   218  C  C    A GLN A 1 17  ? 5.63526   -13.78621 -3.80826 0.505 20.22005 ? 40  GLN A C    1 
ATOM   219  C  C    B GLN A 1 17  ? 5.57973   -13.80801 -3.82076 0.495 20.66461 ? 40  GLN A C    1 
ATOM   220  O  O    A GLN A 1 17  ? 5.48591   -12.80405 -4.54495 0.505 19.68810 ? 40  GLN A O    1 
ATOM   221  O  O    B GLN A 1 17  ? 5.34922   -12.85592 -4.57497 0.495 20.09967 ? 40  GLN A O    1 
ATOM   222  C  CB   A GLN A 1 17  ? 4.94973   -16.01774 -4.62153 0.505 24.79116 ? 40  GLN A CB   1 
ATOM   223  C  CB   B GLN A 1 17  ? 5.01446   -16.06256 -4.72504 0.495 26.19544 ? 40  GLN A CB   1 
ATOM   224  C  CG   A GLN A 1 17  ? 5.22244   -17.18032 -5.53650 0.505 27.75955 ? 40  GLN A CG   1 
ATOM   225  C  CG   B GLN A 1 17  ? 4.05891   -15.54151 -5.78712 0.495 29.39681 ? 40  GLN A CG   1 
ATOM   226  C  CD   A GLN A 1 17  ? 4.02266   -18.09395 -5.65572 0.505 30.63193 ? 40  GLN A CD   1 
ATOM   227  C  CD   B GLN A 1 17  ? 2.95336   -16.52747 -6.12122 0.495 33.08478 ? 40  GLN A CD   1 
ATOM   228  O  OE1  A GLN A 1 17  ? 3.32471   -18.35510 -4.67065 0.505 32.28449 ? 40  GLN A OE1  1 
ATOM   229  O  OE1  B GLN A 1 17  ? 2.89775   -17.62807 -5.56933 0.495 35.15663 ? 40  GLN A OE1  1 
ATOM   230  N  NE2  A GLN A 1 17  ? 3.76336   -18.57155 -6.86397 0.505 32.36126 ? 40  GLN A NE2  1 
ATOM   231  N  NE2  B GLN A 1 17  ? 2.06202   -16.13328 -7.02579 0.495 34.35827 ? 40  GLN A NE2  1 
ATOM   232  H  H    A GLN A 1 17  ? 6.82406   -16.53868 -3.19317 0.505 25.48365 ? 40  GLN A H    1 
ATOM   233  H  H    B GLN A 1 17  ? 6.80246   -16.52073 -3.16709 0.495 26.03580 ? 40  GLN A H    1 
ATOM   234  H  HA   A GLN A 1 17  ? 6.61512   -14.93479 -5.19494 0.505 26.43554 ? 40  GLN A HA   1 
ATOM   235  H  HA   B GLN A 1 17  ? 6.64425   -14.88747 -5.18402 0.495 27.48969 ? 40  GLN A HA   1 
ATOM   236  H  HB2  A GLN A 1 17  ? 4.65213   -16.38005 -3.77237 0.505 29.74940 ? 40  GLN A HB2  1 
ATOM   237  H  HB2  B GLN A 1 17  ? 5.39868   -16.88960 -5.05562 0.495 31.43452 ? 40  GLN A HB2  1 
ATOM   238  H  HB3  A GLN A 1 17  ? 4.24145   -15.49126 -5.02409 0.505 29.74940 ? 40  GLN A HB3  1 
ATOM   239  H  HB3  B GLN A 1 17  ? 4.49688   -16.23453 -3.92290 0.495 31.43452 ? 40  GLN A HB3  1 
ATOM   240  H  HG2  A GLN A 1 17  ? 5.43998   -16.84702 -6.42108 0.505 33.31147 ? 40  GLN A HG2  1 
ATOM   241  H  HG2  B GLN A 1 17  ? 3.64508   -14.72502 -5.46620 0.495 35.27618 ? 40  GLN A HG2  1 
ATOM   242  H  HG3  A GLN A 1 17  ? 5.96434   -17.69692 -5.18491 0.505 33.31147 ? 40  GLN A HG3  1 
ATOM   243  H  HG3  B GLN A 1 17  ? 4.55721   -15.36355 -6.60010 0.495 35.27618 ? 40  GLN A HG3  1 
ATOM   244  H  HE21 A GLN A 1 17  ? 3.09206   -19.09545 -6.98431 0.505 38.83351 ? 40  GLN A HE21 1 
ATOM   245  H  HE21 B GLN A 1 17  ? 1.41646   -16.65564 -7.24939 0.495 41.22992 ? 40  GLN A HE21 1 
ATOM   246  H  HE22 A GLN A 1 17  ? 4.26634   -18.35768 -7.52795 0.505 38.83351 ? 40  GLN A HE22 1 
ATOM   247  H  HE22 B GLN A 1 17  ? 2.13110   -15.35599 -7.38723 0.495 41.22992 ? 40  GLN A HE22 1 
ATOM   248  N  N    . SER A 1 18  ? 5.34414   -13.76016 -2.50759 1.000 18.04856 ? 41  SER A N    1 
ATOM   249  C  CA   . SER A 1 18  ? 4.69623   -12.60347 -1.90613 1.000 16.50506 ? 41  SER A CA   1 
ATOM   250  C  C    . SER A 1 18  ? 5.59575   -11.37667 -1.86379 1.000 16.51967 ? 41  SER A C    1 
ATOM   251  O  O    . SER A 1 18  ? 5.09404   -10.25505 -1.77643 1.000 16.85083 ? 41  SER A O    1 
ATOM   252  C  CB   . SER A 1 18  ? 4.28479   -12.92221 -0.46800 1.000 16.49543 ? 41  SER A CB   1 
ATOM   253  O  OG   . SER A 1 18  ? 5.41312   -12.92235 0.41316  1.000 16.91623 ? 41  SER A OG   1 
ATOM   254  H  H    A SER A 1 18  ? 5.51155   -14.39797 -1.95553 0.505 21.65827 ? 41  SER A H    1 
ATOM   255  H  H    B SER A 1 18  ? 5.54940   -14.38153 -1.94959 0.495 21.65827 ? 41  SER A H    1 
ATOM   256  H  HA   . SER A 1 18  ? 3.91511   -12.40437 -2.44568 1.000 19.80608 ? 41  SER A HA   1 
ATOM   257  H  HB2  . SER A 1 18  ? 3.65268   -12.25080 -0.16711 1.000 19.79451 ? 41  SER A HB2  1 
ATOM   258  H  HB3  . SER A 1 18  ? 3.87163   -13.79958 -0.44772 1.000 19.79451 ? 41  SER A HB3  1 
ATOM   259  H  HG   . SER A 1 18  ? 6.01244   -13.42829 0.11243  1.000 20.29948 ? 41  SER A HG   1 
ATOM   260  N  N    . GLY A 1 19  ? 6.90818   -11.56835 -1.85078 1.000 16.20316 ? 42  GLY A N    1 
ATOM   261  C  CA   . GLY A 1 19  ? 7.84746   -10.47775 -1.70989 1.000 15.35685 ? 42  GLY A CA   1 
ATOM   262  C  C    . GLY A 1 19  ? 8.07265   -9.96914  -0.30254 1.000 15.22183 ? 42  GLY A C    1 
ATOM   263  O  O    . GLY A 1 19  ? 8.90268   -9.07087  -0.12552 1.000 16.65291 ? 42  GLY A O    1 
ATOM   264  H  H    . GLY A 1 19  ? 7.28279   -12.33902 -1.92379 1.000 19.44379 ? 42  GLY A H    1 
ATOM   265  H  HA2  . GLY A 1 19  ? 8.70644   -10.76803 -2.05455 1.000 18.42822 ? 42  GLY A HA2  1 
ATOM   266  H  HA3  . GLY A 1 19  ? 7.53009   -9.73080  -2.24117 1.000 18.42822 ? 42  GLY A HA3  1 
ATOM   267  N  N    . GLY A 1 20  ? 7.38396   -10.51436 0.69887  1.000 12.67428 ? 43  GLY A N    1 
ATOM   268  C  CA   . GLY A 1 20  ? 7.49928   -10.04877 2.06626  1.000 12.75116 ? 43  GLY A CA   1 
ATOM   269  C  C    . GLY A 1 20  ? 8.01943   -11.10484 3.01960  1.000 12.01251 ? 43  GLY A C    1 
ATOM   270  O  O    . GLY A 1 20  ? 8.71609   -12.04161 2.60947  1.000 13.88878 ? 43  GLY A O    1 
ATOM   271  H  H    . GLY A 1 20  ? 6.83350   -11.16833 0.60446  1.000 15.20913 ? 43  GLY A H    1 
ATOM   272  H  HA2  . GLY A 1 20  ? 8.10637   -9.29272  2.09345  1.000 15.30139 ? 43  GLY A HA2  1 
ATOM   273  H  HA3  . GLY A 1 20  ? 6.62624   -9.76414  2.37880  1.000 15.30139 ? 43  GLY A HA3  1 
ATOM   274  N  N    . ARG A 1 21  ? 7.70261   -10.94156 4.29823  1.000 11.28717 ? 44  ARG A N    1 
ATOM   275  C  CA   . ARG A 1 21  ? 8.16949   -11.81203 5.36856  1.000 11.04994 ? 44  ARG A CA   1 
ATOM   276  C  C    . ARG A 1 21  ? 6.92858   -12.40857 6.00860  1.000 11.18798 ? 44  ARG A C    1 
ATOM   277  O  O    . ARG A 1 21  ? 6.06372   -11.66997 6.49284  1.000 10.83928 ? 44  ARG A O    1 
ATOM   278  C  CB   . ARG A 1 21  ? 9.00236   -11.03138 6.38209  1.000 11.32109 ? 44  ARG A CB   1 
ATOM   279  C  CG   . ARG A 1 21  ? 9.62382   -11.89238 7.46905  1.000 12.14194 ? 44  ARG A CG   1 
ATOM   280  C  CD   . ARG A 1 21  ? 10.63273  -11.13311 8.33370  1.000 12.34708 ? 44  ARG A CD   1 
ATOM   281  N  NE   . ARG A 1 21  ? 10.05692  -9.99988  9.04348  1.000 12.39679 ? 44  ARG A NE   1 
ATOM   282  C  CZ   . ARG A 1 21  ? 9.62663   -10.03130 10.29847 1.000 11.42693 ? 44  ARG A CZ   1 
ATOM   283  N  NH1  . ARG A 1 21  ? 9.73509   -11.11502 11.04651 1.000 12.19335 ? 44  ARG A NH1  1 
ATOM   284  N  NH2  . ARG A 1 21  ? 9.09762   -8.93622  10.82324 1.000 12.00930 ? 44  ARG A NH2  1 
ATOM   285  H  H    . ARG A 1 21  ? 7.19696   -10.30639 4.58191  1.000 13.54460 ? 44  ARG A H    1 
ATOM   286  H  HA   . ARG A 1 21  ? 8.73048   -12.52565 5.02660  1.000 13.25993 ? 44  ARG A HA   1 
ATOM   287  H  HB2  . ARG A 1 21  ? 9.72344   -10.58378 5.91241  1.000 13.58531 ? 44  ARG A HB2  1 
ATOM   288  H  HB3  . ARG A 1 21  ? 8.43171   -10.37707 6.81469  1.000 13.58531 ? 44  ARG A HB3  1 
ATOM   289  H  HG2  . ARG A 1 21  ? 8.92086   -12.22143 8.05083  1.000 14.57033 ? 44  ARG A HG2  1 
ATOM   290  H  HG3  . ARG A 1 21  ? 10.08727  -12.63701 7.05475  1.000 14.57033 ? 44  ARG A HG3  1 
ATOM   291  H  HD2  . ARG A 1 21  ? 10.99870  -11.74144 8.99468  1.000 14.81650 ? 44  ARG A HD2  1 
ATOM   292  H  HD3  . ARG A 1 21  ? 11.34199  -10.79628 7.76414  1.000 14.81650 ? 44  ARG A HD3  1 
ATOM   293  H  HE   . ARG A 1 21  ? 9.99076   -9.25534  8.61818  1.000 14.87615 ? 44  ARG A HE   1 
ATOM   294  H  HH11 . ARG A 1 21  ? 10.09281  -11.82693 10.72277 1.000 14.63202 ? 44  ARG A HH11 1 
ATOM   295  H  HH12 . ARG A 1 21  ? 9.44797   -11.10847 11.85714 1.000 14.63202 ? 44  ARG A HH12 1 
ATOM   296  H  HH21 . ARG A 1 21  ? 9.03716   -8.21945  10.35188 1.000 14.41116 ? 44  ARG A HH21 1 
ATOM   297  H  HH22 . ARG A 1 21  ? 8.81461   -8.94199  11.63531 1.000 14.41116 ? 44  ARG A HH22 1 
ATOM   298  N  N    . LEU A 1 22  ? 6.83611   -13.72912 5.97478  1.000 10.89995 ? 45  LEU A N    1 
ATOM   299  C  CA   . LEU A 1 22  ? 5.67167   -14.48411 6.41841  1.000 10.55128 ? 45  LEU A CA   1 
ATOM   300  C  C    . LEU A 1 22  ? 6.00198   -15.25086 7.69162  1.000 10.45123 ? 45  LEU A C    1 
ATOM   301  O  O    . LEU A 1 22  ? 7.04549   -15.91174 7.75891  1.000 12.10934 ? 45  LEU A O    1 
ATOM   302  C  CB   . LEU A 1 22  ? 5.32151   -15.49132 5.32186  1.000 12.01508 ? 45  LEU A CB   1 
ATOM   303  C  CG   . LEU A 1 22  ? 4.19994   -16.47937 5.58136  1.000 12.99847 ? 45  LEU A CG   1 
ATOM   304  C  CD1  . LEU A 1 22  ? 2.88025   -15.74682 5.73074  1.000 13.66229 ? 45  LEU A CD1  1 
ATOM   305  C  CD2  . LEU A 1 22  ? 4.14918   -17.51330 4.47260  1.000 13.86684 ? 45  LEU A CD2  1 
ATOM   306  H  H    . LEU A 1 22  ? 7.46655   -14.23687 5.68438  1.000 13.07994 ? 45  LEU A H    1 
ATOM   307  H  HA   . LEU A 1 22  ? 4.93048   -13.88801 6.60865  1.000 12.66153 ? 45  LEU A HA   1 
ATOM   308  H  HB2  . LEU A 1 22  ? 5.06995   -14.98831 4.53155  1.000 14.41809 ? 45  LEU A HB2  1 
ATOM   309  H  HB3  . LEU A 1 22  ? 6.11688   -16.01649 5.14163  1.000 14.41809 ? 45  LEU A HB3  1 
ATOM   310  H  HG   . LEU A 1 22  ? 4.36162   -16.95321 6.41216  1.000 15.59816 ? 45  LEU A HG   1 
ATOM   311  H  HD11 . LEU A 1 22  ? 2.16338   -16.39724 5.79373  1.000 16.39475 ? 45  LEU A HD11 1 
ATOM   312  H  HD12 . LEU A 1 22  ? 2.90835   -15.20651 6.53584  1.000 16.39475 ? 45  LEU A HD12 1 
ATOM   313  H  HD13 . LEU A 1 22  ? 2.74470   -15.17915 4.95597  1.000 16.39475 ? 45  LEU A HD13 1 
ATOM   314  H  HD21 . LEU A 1 22  ? 3.43605   -18.14334 4.66073  1.000 16.64021 ? 45  LEU A HD21 1 
ATOM   315  H  HD22 . LEU A 1 22  ? 3.98001   -17.06429 3.62959  1.000 16.64021 ? 45  LEU A HD22 1 
ATOM   316  H  HD23 . LEU A 1 22  ? 4.99977   -17.97804 4.43499  1.000 16.64021 ? 45  LEU A HD23 1 
ATOM   317  N  N    . GLY A 1 23  ? 5.09031   -15.19514 8.66850  1.000 9.78246  ? 46  GLY A N    1 
ATOM   318  C  CA   . GLY A 1 23  ? 5.22372   -15.93578 9.91017  1.000 9.53762  ? 46  GLY A CA   1 
ATOM   319  C  C    . GLY A 1 23  ? 3.97281   -16.75465 10.15011 1.000 9.76456  ? 46  GLY A C    1 
ATOM   320  O  O    . GLY A 1 23  ? 2.85854   -16.23157 10.08967 1.000 10.15895 ? 46  GLY A O    1 
ATOM   321  H  H    . GLY A 1 23  ? 4.37243   -14.72327 8.62869  1.000 11.73895 ? 46  GLY A H    1 
ATOM   322  H  HA2  . GLY A 1 23  ? 5.98827   -16.53071 9.86097  1.000 11.44515 ? 46  GLY A HA2  1 
ATOM   323  H  HA3  . GLY A 1 23  ? 5.34842   -15.32187 10.65076 1.000 11.44515 ? 46  GLY A HA3  1 
ATOM   324  N  N    . VAL A 1 24  ? 4.13376   -18.04918 10.37082 1.000 9.77028  ? 47  VAL A N    1 
ATOM   325  C  CA   . VAL A 1 24  ? 3.00891   -18.95589 10.53178 1.000 9.62133  ? 47  VAL A CA   1 
ATOM   326  C  C    . VAL A 1 24  ? 3.23283   -19.84116 11.74516 1.000 9.82424  ? 47  VAL A C    1 
ATOM   327  O  O    . VAL A 1 24  ? 4.31888   -20.39535 11.93815 1.000 10.55720 ? 47  VAL A O    1 
ATOM   328  C  CB   . VAL A 1 24  ? 2.81217   -19.82576 9.26981  1.000 10.39226 ? 47  VAL A CB   1 
ATOM   329  C  CG1  . VAL A 1 24  ? 1.65141   -20.79744 9.47092  1.000 12.17224 ? 47  VAL A CG1  1 
ATOM   330  C  CG2  . VAL A 1 24  ? 2.58331   -18.96896 8.04427  1.000 11.63719 ? 47  VAL A CG2  1 
ATOM   331  H  H    . VAL A 1 24  ? 4.90044   -18.43386 10.43269 1.000 11.72434 ? 47  VAL A H    1 
ATOM   332  H  HA   . VAL A 1 24  ? 2.20808   -18.43245 10.69170 1.000 11.54560 ? 47  VAL A HA   1 
ATOM   333  H  HB   . VAL A 1 24  ? 3.62160   -20.33923 9.12121  1.000 12.47072 ? 47  VAL A HB   1 
ATOM   334  H  HG11 . VAL A 1 24  ? 1.48298   -21.26496 8.63788  1.000 14.60669 ? 47  VAL A HG11 1 
ATOM   335  H  HG12 . VAL A 1 24  ? 1.88792   -21.43269 10.16477 1.000 14.60669 ? 47  VAL A HG12 1 
ATOM   336  H  HG13 . VAL A 1 24  ? 0.86318   -20.29752 9.73488  1.000 14.60669 ? 47  VAL A HG13 1 
ATOM   337  H  HG21 . VAL A 1 24  ? 2.48696   -19.54495 7.26976  1.000 13.96463 ? 47  VAL A HG21 1 
ATOM   338  H  HG22 . VAL A 1 24  ? 1.77581   -18.44655 8.17048  1.000 13.96463 ? 47  VAL A HG22 1 
ATOM   339  H  HG23 . VAL A 1 24  ? 3.34383   -18.37880 7.92503  1.000 13.96463 ? 47  VAL A HG23 1 
ATOM   340  N  N    . ALA A 1 25  ? 2.18520   -20.00968 12.54549 1.000 9.91455  ? 48  ALA A N    1 
ATOM   341  C  CA   . ALA A 1 25  ? 2.16582   -21.06907 13.53969 1.000 10.20176 ? 48  ALA A CA   1 
ATOM   342  C  C    . ALA A 1 25  ? 0.77756   -21.68479 13.57224 1.000 9.33670  ? 48  ALA A C    1 
ATOM   343  O  O    . ALA A 1 25  ? -0.20906  -20.99882 13.84671 1.000 9.83461  ? 48  ALA A O    1 
ATOM   344  C  CB   . ALA A 1 25  ? 2.55345   -20.53953 14.92000 1.000 10.02335 ? 48  ALA A CB   1 
ATOM   345  H  H    . ALA A 1 25  ? 1.47658   -19.52264 12.52954 1.000 11.89746 ? 48  ALA A H    1 
ATOM   346  H  HA   . ALA A 1 25  ? 2.79904   -21.75919 13.28737 1.000 12.24211 ? 48  ALA A HA   1 
ATOM   347  H  HB1  . ALA A 1 25  ? 2.45913   -21.25332 15.57001 1.000 12.02802 ? 48  ALA A HB1  1 
ATOM   348  H  HB2  . ALA A 1 25  ? 3.47406   -20.23505 14.89434 1.000 12.02802 ? 48  ALA A HB2  1 
ATOM   349  H  HB3  . ALA A 1 25  ? 1.96744   -19.80197 15.15129 1.000 12.02802 ? 48  ALA A HB3  1 
ATOM   350  N  N    . LEU A 1 26  ? 0.71364   -22.96835 13.25617 1.000 10.10262 ? 49  LEU A N    1 
ATOM   351  C  CA   . LEU A 1 26  ? -0.48225  -23.77717 13.40382 1.000 10.13408 ? 49  LEU A CA   1 
ATOM   352  C  C    . LEU A 1 26  ? -0.27261  -24.73212 14.56621 1.000 11.09633 ? 49  LEU A C    1 
ATOM   353  O  O    . LEU A 1 26  ? 0.75778   -25.40337 14.62712 1.000 12.22195 ? 49  LEU A O    1 
ATOM   354  C  CB   . LEU A 1 26  ? -0.69699  -24.59035 12.12585 1.000 11.31776 ? 49  LEU A CB   1 
ATOM   355  C  CG   . LEU A 1 26  ? -1.87439  -25.55427 12.18195 1.000 12.66236 ? 49  LEU A CG   1 
ATOM   356  C  CD1  . LEU A 1 26  ? -3.21830  -24.89304 12.01619 1.000 13.88280 ? 49  LEU A CD1  1 
ATOM   357  C  CD2  . LEU A 1 26  ? -1.69046  -26.67664 11.13771 1.000 15.98061 ? 49  LEU A CD2  1 
ATOM   358  H  H    . LEU A 1 26  ? 1.37987   -23.41121 12.94055 1.000 12.12314 ? 49  LEU A H    1 
ATOM   359  H  HA   . LEU A 1 26  ? -1.25782  -23.22173 13.57953 1.000 12.16089 ? 49  LEU A HA   1 
ATOM   360  H  HB2  . LEU A 1 26  ? -0.85517  -23.97580 11.39223 1.000 13.58131 ? 49  LEU A HB2  1 
ATOM   361  H  HB3  . LEU A 1 26  ? 0.10230   -25.11259 11.95469 1.000 13.58131 ? 49  LEU A HB3  1 
ATOM   362  H  HG   . LEU A 1 26  ? -1.88351  -25.93491 13.07410 1.000 15.19484 ? 49  LEU A HG   1 
ATOM   363  H  HD11 . LEU A 1 26  ? -3.91284  -25.56589 12.09228 1.000 16.65936 ? 49  LEU A HD11 1 
ATOM   364  H  HD12 . LEU A 1 26  ? -3.32867  -24.22383 12.70964 1.000 16.65936 ? 49  LEU A HD12 1 
ATOM   365  H  HD13 . LEU A 1 26  ? -3.25831  -24.47370 11.14243 1.000 16.65936 ? 49  LEU A HD13 1 
ATOM   366  H  HD21 . LEU A 1 26  ? -2.51119  -27.19022 11.07821 1.000 19.17673 ? 49  LEU A HD21 1 
ATOM   367  H  HD22 . LEU A 1 26  ? -1.48702  -26.27735 10.27744 1.000 19.17673 ? 49  LEU A HD22 1 
ATOM   368  H  HD23 . LEU A 1 26  ? -0.96032  -27.25104 11.41675 1.000 19.17673 ? 49  LEU A HD23 1 
ATOM   369  N  N    . ILE A 1 27  ? -1.26202  -24.80508 15.46167 1.000 10.81605 ? 50  ILE A N    1 
ATOM   370  C  CA   . ILE A 1 27  ? -1.33837  -25.85177 16.48111 1.000 11.04508 ? 50  ILE A CA   1 
ATOM   371  C  C    . ILE A 1 27  ? -2.52639  -26.72945 16.12971 1.000 11.63488 ? 50  ILE A C    1 
ATOM   372  O  O    . ILE A 1 27  ? -3.65902  -26.23798 16.01042 1.000 12.34092 ? 50  ILE A O    1 
ATOM   373  C  CB   . ILE A 1 27  ? -1.51266  -25.28404 17.89724 1.000 11.34558 ? 50  ILE A CB   1 
ATOM   374  C  CG1  . ILE A 1 27  ? -0.37029  -24.32700 18.26485 1.000 12.19852 ? 50  ILE A CG1  1 
ATOM   375  C  CG2  . ILE A 1 27  ? -1.61296  -26.42739 18.91845 1.000 12.35138 ? 50  ILE A CG2  1 
ATOM   376  C  CD1  . ILE A 1 27  ? -0.65489  -23.51259 19.53532 1.000 13.25349 ? 50  ILE A CD1  1 
ATOM   377  H  H    . ILE A 1 27  ? -1.91432  -24.24578 15.49754 1.000 12.97926 ? 50  ILE A H    1 
ATOM   378  H  HA   . ILE A 1 27  ? -0.51913  -26.37068 16.45930 1.000 13.25410 ? 50  ILE A HA   1 
ATOM   379  H  HB   . ILE A 1 27  ? -2.33727  -24.77348 17.91278 1.000 13.61469 ? 50  ILE A HB   1 
ATOM   380  H  HG12 . ILE A 1 27  ? 0.43696   -24.84342 18.41502 1.000 14.63823 ? 50  ILE A HG12 1 
ATOM   381  H  HG13 . ILE A 1 27  ? -0.23431  -23.70378 17.53410 1.000 14.63823 ? 50  ILE A HG13 1 
ATOM   382  H  HG21 . ILE A 1 27  ? -1.69936  -26.04983 19.80776 1.000 14.82165 ? 50  ILE A HG21 1 
ATOM   383  H  HG22 . ILE A 1 27  ? -2.39121  -26.96817 18.71163 1.000 14.82165 ? 50  ILE A HG22 1 
ATOM   384  H  HG23 . ILE A 1 27  ? -0.81015  -26.96925 18.86571 1.000 14.82165 ? 50  ILE A HG23 1 
ATOM   385  H  HD11 . ILE A 1 27  ? 0.10444   -22.93745 19.71845 1.000 15.90419 ? 50  ILE A HD11 1 
ATOM   386  H  HD12 . ILE A 1 27  ? -1.45029  -22.97553 19.39460 1.000 15.90419 ? 50  ILE A HD12 1 
ATOM   387  H  HD13 . ILE A 1 27  ? -0.79438  -24.12236 20.27668 1.000 15.90419 ? 50  ILE A HD13 1 
ATOM   388  N  N    . ASN A 1 28  ? -2.27381  -28.01825 15.95053 1.000 12.75346 ? 51  ASN A N    1 
ATOM   389  C  CA   . ASN A 1 28  ? -3.34057  -28.97437 15.72236 1.000 13.75451 ? 51  ASN A CA   1 
ATOM   390  C  C    . ASN A 1 28  ? -3.56571  -29.67618 17.05273 1.000 14.97110 ? 51  ASN A C    1 
ATOM   391  O  O    . ASN A 1 28  ? -2.71607  -30.45516 17.50515 1.000 15.88056 ? 51  ASN A O    1 
ATOM   392  C  CB   . ASN A 1 28  ? -2.95761  -29.96908 14.63876 1.000 15.70652 ? 51  ASN A CB   1 
ATOM   393  C  CG   . ASN A 1 28  ? -4.08752  -30.90461 14.31023 1.000 17.70993 ? 51  ASN A CG   1 
ATOM   394  O  OD1  . ASN A 1 28  ? -5.04735  -31.02527 15.07190 1.000 17.11215 ? 51  ASN A OD1  1 
ATOM   395  N  ND2  . ASN A 1 28  ? -3.99120  -31.56650 13.16654 1.000 20.81997 ? 51  ASN A ND2  1 
ATOM   396  H  H    . ASN A 1 28  ? -1.48591  -28.36286 15.95732 1.000 15.30415 ? 51  ASN A H    1 
ATOM   397  H  HA   . ASN A 1 28  ? -4.15191  -28.52696 15.43521 1.000 16.50541 ? 51  ASN A HA   1 
ATOM   398  H  HB2  . ASN A 1 28  ? -2.71923  -29.48619 13.83198 1.000 18.84782 ? 51  ASN A HB2  1 
ATOM   399  H  HB3  . ASN A 1 28  ? -2.20413  -30.49858 14.94335 1.000 18.84782 ? 51  ASN A HB3  1 
ATOM   400  H  HD21 . ASN A 1 28  ? -4.61190  -32.11402 12.93299 1.000 24.98397 ? 51  ASN A HD21 1 
ATOM   401  H  HD22 . ASN A 1 28  ? -3.30797  -31.44861 12.65771 1.000 24.98397 ? 51  ASN A HD22 1 
ATOM   402  N  N    . THR A 1 29  ? -4.70026  -29.39768 17.68255 1.000 15.61210 ? 52  THR A N    1 
ATOM   403  C  CA   . THR A 1 29  ? -4.90690  -29.93291 19.02125 1.000 16.52783 ? 52  THR A CA   1 
ATOM   404  C  C    . THR A 1 29  ? -5.23815  -31.42087 19.01902 1.000 19.45289 ? 52  THR A C    1 
ATOM   405  O  O    . THR A 1 29  ? -5.26157  -32.02965 20.08965 1.000 20.64326 ? 52  THR A O    1 
ATOM   406  C  CB   . THR A 1 29  ? -5.95745  -29.15585 19.82090 1.000 16.34566 ? 52  THR A CB   1 
ATOM   407  O  OG1  . THR A 1 29  ? -7.25970  -29.38317 19.26636 1.000 17.43100 ? 52  THR A OG1  1 
ATOM   408  C  CG2  . THR A 1 29  ? -5.62689  -27.67177 19.85194 1.000 15.59086 ? 52  THR A CG2  1 
ATOM   409  H  H    . THR A 1 29  ? -5.34176  -28.91908 17.36788 1.000 18.73452 ? 52  THR A H    1 
ATOM   410  H  HA   . THR A 1 29  ? -4.07681  -29.80531 19.50659 1.000 19.83340 ? 52  THR A HA   1 
ATOM   411  H  HB   . THR A 1 29  ? -5.96207  -29.46499 20.74031 1.000 19.61479 ? 52  THR A HB   1 
ATOM   412  H  HG1  . THR A 1 29  ? -7.34106  -28.96409 18.54293 1.000 20.91720 ? 52  THR A HG1  1 
ATOM   413  H  HG21 . THR A 1 29  ? -6.26927  -27.20030 20.40507 1.000 18.70903 ? 52  THR A HG21 1 
ATOM   414  H  HG22 . THR A 1 29  ? -4.73839  -27.53735 20.21718 1.000 18.70903 ? 52  THR A HG22 1 
ATOM   415  H  HG23 . THR A 1 29  ? -5.65667  -27.30640 18.95388 1.000 18.70903 ? 52  THR A HG23 1 
ATOM   416  N  N    . ALA A 1 30  ? -5.46757  -32.02424 17.85439 1.000 20.36450 ? 53  ALA A N    1 
ATOM   417  C  CA   . ALA A 1 30  ? -5.69485  -33.46688 17.82135 1.000 21.88805 ? 53  ALA A CA   1 
ATOM   418  C  C    . ALA A 1 30  ? -4.50037  -34.22866 18.38397 1.000 23.00052 ? 53  ALA A C    1 
ATOM   419  O  O    . ALA A 1 30  ? -4.66330  -35.19762 19.14565 1.000 24.30580 ? 53  ALA A O    1 
ATOM   420  C  CB   . ALA A 1 30  ? -5.96529  -33.91500 16.38557 1.000 22.56985 ? 53  ALA A CB   1 
ATOM   421  H  H    . ALA A 1 30  ? -5.49625  -31.63261 17.08928 1.000 24.43740 ? 53  ALA A H    1 
ATOM   422  H  HA   . ALA A 1 30  ? -6.47211  -33.67141 18.36442 1.000 26.26566 ? 53  ALA A HA   1 
ATOM   423  H  HB1  . ALA A 1 30  ? -6.13907  -34.86929 16.38001 1.000 27.08382 ? 53  ALA A HB1  1 
ATOM   424  H  HB2  . ALA A 1 30  ? -6.73728  -33.43621 16.04541 1.000 27.08382 ? 53  ALA A HB2  1 
ATOM   425  H  HB3  . ALA A 1 30  ? -5.18718  -33.71731 15.84117 1.000 27.08382 ? 53  ALA A HB3  1 
ATOM   426  N  N    . ASP A 1 31  ? -3.28991  -33.82318 17.99799 1.000 22.41970 ? 54  ASP A N    1 
ATOM   427  C  CA   . ASP A 1 31  ? -2.07075  -34.52344 18.37828 1.000 23.31789 ? 54  ASP A CA   1 
ATOM   428  C  C    . ASP A 1 31  ? -1.02613  -33.59395 18.98260 1.000 20.72439 ? 54  ASP A C    1 
ATOM   429  O  O    . ASP A 1 31  ? 0.12233   -34.01648 19.16925 1.000 21.09057 ? 54  ASP A O    1 
ATOM   430  C  CB   . ASP A 1 31  ? -1.48598  -35.29620 17.18288 1.000 26.01023 ? 54  ASP A CB   1 
ATOM   431  C  CG   . ASP A 1 31  ? -1.21911  -34.41238 15.97283 1.000 28.84017 ? 54  ASP A CG   1 
ATOM   432  O  OD1  . ASP A 1 31  ? -1.47884  -33.20353 16.03589 1.000 26.55382 ? 54  ASP A OD1  1 
ATOM   433  O  OD2  . ASP A 1 31  ? -0.74483  -34.93631 14.94045 1.000 31.30221 ? 54  ASP A OD2  1 
ATOM   434  H  H    . ASP A 1 31  ? -3.14949  -33.13176 17.50623 1.000 26.90364 ? 54  ASP A H    1 
ATOM   435  H  HA   . ASP A 1 31  ? -2.29158  -35.17997 19.05733 1.000 27.98146 ? 54  ASP A HA   1 
ATOM   436  H  HB2  . ASP A 1 31  ? -0.64481  -35.69893 17.44958 1.000 31.21227 ? 54  ASP A HB2  1 
ATOM   437  H  HB3  . ASP A 1 31  ? -2.11406  -35.98560 16.91616 1.000 31.21227 ? 54  ASP A HB3  1 
ATOM   438  N  N    . ASN A 1 32  ? -1.39019  -32.34824 19.29823 1.000 18.23394 ? 55  ASN A N    1 
ATOM   439  C  CA   . ASN A 1 32  ? -0.45251  -31.39180 19.87801 1.000 18.07824 ? 55  ASN A CA   1 
ATOM   440  C  C    . ASN A 1 32  ? 0.75210   -31.19891 18.96639 1.000 18.54142 ? 55  ASN A C    1 
ATOM   441  O  O    . ASN A 1 32  ? 1.88312   -31.06116 19.42719 1.000 20.60438 ? 55  ASN A O    1 
ATOM   442  C  CB   . ASN A 1 32  ? -0.01475  -31.79700 21.28889 1.000 19.68785 ? 55  ASN A CB   1 
ATOM   443  C  CG   . ASN A 1 32  ? 0.56594   -30.64268 22.08292 1.000 21.28337 ? 55  ASN A CG   1 
ATOM   444  O  OD1  . ASN A 1 32  ? 0.19370   -29.48913 21.88124 1.000 20.24707 ? 55  ASN A OD1  1 
ATOM   445  N  ND2  . ASN A 1 32  ? 1.49207   -30.95049 22.98952 1.000 21.53678 ? 55  ASN A ND2  1 
ATOM   446  H  H    . ASN A 1 32  ? -2.18229  -32.03342 19.18392 1.000 21.88073 ? 55  ASN A H    1 
ATOM   447  H  HA   . ASN A 1 32  ? -0.90573  -30.53801 19.95881 1.000 21.69389 ? 55  ASN A HA   1 
ATOM   448  H  HB2  . ASN A 1 32  ? -0.78430  -32.13554 21.77271 1.000 23.62542 ? 55  ASN A HB2  1 
ATOM   449  H  HB3  . ASN A 1 32  ? 0.66477   -32.48600 21.22245 1.000 23.62542 ? 55  ASN A HB3  1 
ATOM   450  H  HD21 . ASN A 1 32  ? 1.85126   -30.33037 23.46494 1.000 25.84413 ? 55  ASN A HD21 1 
ATOM   451  H  HD22 . ASN A 1 32  ? 1.73082   -31.76935 23.09940 1.000 25.84413 ? 55  ASN A HD22 1 
ATOM   452  N  N    . SER A 1 33  ? 0.50524   -31.18689 17.66343 1.000 18.11580 ? 56  SER A N    1 
ATOM   453  C  CA   . SER A 1 33  ? 1.54951   -30.92955 16.68965 1.000 18.45148 ? 56  SER A CA   1 
ATOM   454  C  C    . SER A 1 33  ? 1.47567   -29.48339 16.22965 1.000 16.96860 ? 56  SER A C    1 
ATOM   455  O  O    . SER A 1 33  ? 0.45845   -28.81300 16.37665 1.000 15.72659 ? 56  SER A O    1 
ATOM   456  C  CB   . SER A 1 33  ? 1.43548   -31.86627 15.48807 1.000 20.57743 ? 56  SER A CB   1 
ATOM   457  O  OG   . SER A 1 33  ? 0.25281   -31.63100 14.74711 1.000 22.62298 ? 56  SER A OG   1 
ATOM   458  H  H    . SER A 1 33  ? -0.26957  -31.32707 17.31757 1.000 21.73896 ? 56  SER A H    1 
ATOM   459  H  HA   . SER A 1 33  ? 2.41478   -31.08749 17.09864 1.000 22.14177 ? 56  SER A HA   1 
ATOM   460  H  HB2  . SER A 1 33  ? 2.20004   -31.72407 14.90831 1.000 24.69292 ? 56  SER A HB2  1 
ATOM   461  H  HB3  . SER A 1 33  ? 1.42662   -32.78239 15.80674 1.000 24.69292 ? 56  SER A HB3  1 
ATOM   462  H  HG   . SER A 1 33  ? -0.42046  -31.81431 15.21477 1.000 27.14758 ? 56  SER A HG   1 
ATOM   463  N  N    . GLN A 1 34  ? 2.57336   -29.02692 15.65027 1.000 17.12253 ? 57  GLN A N    1 
ATOM   464  C  CA   . GLN A 1 34  ? 2.68837   -27.66970 15.16114 1.000 15.95694 ? 57  GLN A CA   1 
ATOM   465  C  C    . GLN A 1 34  ? 3.30671   -27.65285 13.77112 1.000 15.86707 ? 57  GLN A C    1 
ATOM   466  O  O    . GLN A 1 34  ? 4.13431   -28.50332 13.41833 1.000 18.32735 ? 57  GLN A O    1 
ATOM   467  C  CB   . GLN A 1 34  ? 3.58536   -26.83058 16.08314 1.000 18.40507 ? 57  GLN A CB   1 
ATOM   468  C  CG   . GLN A 1 34  ? 3.09967   -26.67611 17.50303 1.000 23.22885 ? 57  GLN A CG   1 
ATOM   469  C  CD   . GLN A 1 34  ? 4.09970   -25.91250 18.35175 1.000 26.62085 ? 57  GLN A CD   1 
ATOM   470  O  OE1  . GLN A 1 34  ? 3.89633   -24.74044 18.68069 1.000 29.06658 ? 57  GLN A OE1  1 
ATOM   471  N  NE2  . GLN A 1 34  ? 5.19321   -26.57414 18.70651 1.000 29.80754 ? 57  GLN A NE2  1 
ATOM   472  H  H    . GLN A 1 34  ? 3.28191   -29.49847 15.52698 1.000 20.54703 ? 57  GLN A H    1 
ATOM   473  H  HA   . GLN A 1 34  ? 1.80036   -27.28256 15.11159 1.000 19.14833 ? 57  GLN A HA   1 
ATOM   474  H  HB2  . GLN A 1 34  ? 4.45921   -27.24988 16.12167 1.000 22.08609 ? 57  GLN A HB2  1 
ATOM   475  H  HB3  . GLN A 1 34  ? 3.66102   -25.94005 15.70614 1.000 22.08609 ? 57  GLN A HB3  1 
ATOM   476  H  HG2  . GLN A 1 34  ? 2.26177   -26.18743 17.50440 1.000 27.87463 ? 57  GLN A HG2  1 
ATOM   477  H  HG3  . GLN A 1 34  ? 2.97255   -27.55371 17.89618 1.000 27.87463 ? 57  GLN A HG3  1 
ATOM   478  H  HE21 . GLN A 1 34  ? 5.30307   -27.38928 18.45537 1.000 35.76905 ? 57  GLN A HE21 1 
ATOM   479  H  HE22 . GLN A 1 34  ? 5.79235   -26.18798 19.18768 1.000 35.76905 ? 57  GLN A HE22 1 
ATOM   480  N  N    . ILE A 1 35  ? 2.88315   -26.66681 12.98628 1.000 13.50454 ? 58  ILE A N    1 
ATOM   481  C  CA   . ILE A 1 35  ? 3.56089   -26.28253 11.75098 1.000 12.90266 ? 58  ILE A CA   1 
ATOM   482  C  C    . ILE A 1 35  ? 4.02999   -24.85257 11.95640 1.000 12.53082 ? 58  ILE A C    1 
ATOM   483  O  O    . ILE A 1 35  ? 3.21794   -23.97788 12.26306 1.000 12.29929 ? 58  ILE A O    1 
ATOM   484  C  CB   . ILE A 1 35  ? 2.66100   -26.40885 10.51534 1.000 14.37047 ? 58  ILE A CB   1 
ATOM   485  C  CG1  . ILE A 1 35  ? 2.24213   -27.87288 10.33191 1.000 17.69596 ? 58  ILE A CG1  1 
ATOM   486  C  CG2  . ILE A 1 35  ? 3.41921   -25.90679 9.29121  1.000 15.81123 ? 58  ILE A CG2  1 
ATOM   487  C  CD1  . ILE A 1 35  ? 1.27107   -28.13262 9.19291  1.000 19.92420 ? 58  ILE A CD1  1 
ATOM   488  H  H    . ILE A 1 35  ? 2.18559   -26.19226 13.15303 1.000 16.20545 ? 58  ILE A H    1 
ATOM   489  H  HA   . ILE A 1 35  ? 4.32716   -26.85712 11.59744 1.000 15.48319 ? 58  ILE A HA   1 
ATOM   490  H  HB   . ILE A 1 35  ? 1.86117   -25.87292 10.63349 1.000 17.24457 ? 58  ILE A HB   1 
ATOM   491  H  HG12 . ILE A 1 35  ? 3.03824   -28.39946 10.15926 1.000 21.23515 ? 58  ILE A HG12 1 
ATOM   492  H  HG13 . ILE A 1 35  ? 1.81615   -28.17391 11.14973 1.000 21.23515 ? 58  ILE A HG13 1 
ATOM   493  H  HG21 . ILE A 1 35  ? 2.84902   -25.98923 8.51083  1.000 18.97348 ? 58  ILE A HG21 1 
ATOM   494  H  HG22 . ILE A 1 35  ? 3.66001   -24.97720 9.42822  1.000 18.97348 ? 58  ILE A HG22 1 
ATOM   495  H  HG23 . ILE A 1 35  ? 4.21964   -26.44203 9.17407  1.000 18.97348 ? 58  ILE A HG23 1 
ATOM   496  H  HD11 . ILE A 1 35  ? 0.93606   -29.04012 9.26429  1.000 23.90904 ? 58  ILE A HD11 1 
ATOM   497  H  HD12 . ILE A 1 35  ? 0.53595   -27.50281 9.25483  1.000 23.90904 ? 58  ILE A HD12 1 
ATOM   498  H  HD13 . ILE A 1 35  ? 1.73562   -28.01690 8.34929  1.000 23.90904 ? 58  ILE A HD13 1 
ATOM   499  N  N    . LEU A 1 36  ? 5.32865   -24.62794 11.80951 1.000 12.68860 ? 59  LEU A N    1 
ATOM   500  C  CA   . LEU A 1 36  ? 5.96611   -23.37432 12.16295 1.000 12.97520 ? 59  LEU A CA   1 
ATOM   501  C  C    . LEU A 1 36  ? 6.78232   -22.85652 10.99319 1.000 13.09806 ? 59  LEU A C    1 
ATOM   502  O  O    . LEU A 1 36  ? 7.53173   -23.60414 10.35716 1.000 15.12688 ? 59  LEU A O    1 
ATOM   503  C  CB   . LEU A 1 36  ? 6.90403   -23.58590 13.35087 1.000 13.72006 ? 59  LEU A CB   1 
ATOM   504  C  CG   . LEU A 1 36  ? 6.24979   -24.16952 14.59184 1.000 15.24189 ? 59  LEU A CG   1 
ATOM   505  C  CD1  . LEU A 1 36  ? 7.31739   -24.46620 15.63245 1.000 18.66712 ? 59  LEU A CD1  1 
ATOM   506  C  CD2  . LEU A 1 36  ? 5.18275   -23.24332 15.16633 1.000 15.20321 ? 59  LEU A CD2  1 
ATOM   507  H  H    . LEU A 1 36  ? 5.87887   -25.20948 11.49540 1.000 15.22632 ? 59  LEU A H    1 
ATOM   508  H  HA   . LEU A 1 36  ? 5.28912   -22.71439 12.37992 1.000 15.57023 ? 59  LEU A HA   1 
ATOM   509  H  HB2  . LEU A 1 36  ? 7.60886   -24.19464 13.07966 1.000 16.46407 ? 59  LEU A HB2  1 
ATOM   510  H  HB3  . LEU A 1 36  ? 7.28342   -22.72802 13.59784 1.000 16.46407 ? 59  LEU A HB3  1 
ATOM   511  H  HG   . LEU A 1 36  ? 5.79909   -24.99332 14.34867 1.000 18.29027 ? 59  LEU A HG   1 
ATOM   512  H  HD11 . LEU A 1 36  ? 6.90099   -24.88643 16.40116 1.000 22.40054 ? 59  LEU A HD11 1 
ATOM   513  H  HD12 . LEU A 1 36  ? 7.97750   -25.06295 15.24640 1.000 22.40054 ? 59  LEU A HD12 1 
ATOM   514  H  HD13 . LEU A 1 36  ? 7.73907   -23.63411 15.89837 1.000 22.40054 ? 59  LEU A HD13 1 
ATOM   515  H  HD21 . LEU A 1 36  ? 4.84297   -23.62586 15.99041 1.000 18.24385 ? 59  LEU A HD21 1 
ATOM   516  H  HD22 . LEU A 1 36  ? 5.57941   -22.37597 15.34315 1.000 18.24385 ? 59  LEU A HD22 1 
ATOM   517  H  HD23 . LEU A 1 36  ? 4.46311   -23.15283 14.52226 1.000 18.24385 ? 59  LEU A HD23 1 
ATOM   518  N  N    . TYR A 1 37  ? 6.67132   -21.55763 10.74918 1.000 11.83312 ? 60  TYR A N    1 
ATOM   519  C  CA   . TYR A 1 37  ? 7.46801   -20.90606 9.71463  1.000 11.58047 ? 60  TYR A CA   1 
ATOM   520  C  C    . TYR A 1 37  ? 7.80166   -19.51033 10.23273 1.000 11.32498 ? 60  TYR A C    1 
ATOM   521  O  O    . TYR A 1 37  ? 6.89920   -18.71179 10.47466 1.000 11.30685 ? 60  TYR A O    1 
ATOM   522  C  CB   . TYR A 1 37  ? 6.70528   -20.83654 8.37778  1.000 12.62718 ? 60  TYR A CB   1 
ATOM   523  C  CG   . TYR A 1 37  ? 7.56333   -20.34098 7.22992  1.000 13.16088 ? 60  TYR A CG   1 
ATOM   524  C  CD1  . TYR A 1 37  ? 8.33713   -21.22090 6.47124  1.000 14.39868 ? 60  TYR A CD1  1 
ATOM   525  C  CD2  . TYR A 1 37  ? 7.63513   -18.99377 6.91058  1.000 13.21553 ? 60  TYR A CD2  1 
ATOM   526  C  CE1  . TYR A 1 37  ? 9.14149   -20.76899 5.44550  1.000 15.26622 ? 60  TYR A CE1  1 
ATOM   527  C  CE2  . TYR A 1 37  ? 8.44537   -18.53629 5.88150  1.000 13.77678 ? 60  TYR A CE2  1 
ATOM   528  C  CZ   . TYR A 1 37  ? 9.20354   -19.43146 5.15512  1.000 15.17704 ? 60  TYR A CZ   1 
ATOM   529  O  OH   . TYR A 1 37  ? 10.01425  -19.01199 4.13840  1.000 16.70077 ? 60  TYR A OH   1 
ATOM   530  H  H    . TYR A 1 37  ? 6.13972   -21.02884 11.17036 1.000 14.19974 ? 60  TYR A H    1 
ATOM   531  H  HA   . TYR A 1 37  ? 8.28961   -21.39533 9.55185  1.000 13.89657 ? 60  TYR A HA   1 
ATOM   532  H  HB2  . TYR A 1 37  ? 6.38610   -21.72405 8.15117  1.000 15.15261 ? 60  TYR A HB2  1 
ATOM   533  H  HB3  . TYR A 1 37  ? 5.95537   -20.22898 8.47466  1.000 15.15261 ? 60  TYR A HB3  1 
ATOM   534  H  HD1  . TYR A 1 37  ? 8.30986   -22.13088 6.66123  1.000 17.27841 ? 60  TYR A HD1  1 
ATOM   535  H  HD2  . TYR A 1 37  ? 7.12914   -18.38345 7.39677  1.000 15.85863 ? 60  TYR A HD2  1 
ATOM   536  H  HE1  . TYR A 1 37  ? 9.64347   -21.37454 4.94929  1.000 18.31946 ? 60  TYR A HE1  1 
ATOM   537  H  HE2  . TYR A 1 37  ? 8.47740   -17.62856 5.68178  1.000 16.53214 ? 60  TYR A HE2  1 
ATOM   538  H  HH   . TYR A 1 37  ? 10.06639  -18.17361 4.13977  1.000 20.04092 ? 60  TYR A HH   1 
ATOM   539  N  N    . ARG A 1 38  ? 9.08356   -19.22671 10.43929 1.000 11.66601 ? 61  ARG A N    1 
ATOM   540  C  CA   . ARG A 1 38  ? 9.51379   -17.98163 11.08195 1.000 11.90824 ? 61  ARG A CA   1 
ATOM   541  C  C    . ARG A 1 38  ? 8.77001   -17.74918 12.39350 1.000 11.22924 ? 61  ARG A C    1 
ATOM   542  O  O    . ARG A 1 38  ? 8.47869   -16.61302 12.77886 1.000 11.85608 ? 61  ARG A O    1 
ATOM   543  C  CB   . ARG A 1 38  ? 9.38282   -16.77495 10.15531 1.000 11.61176 ? 61  ARG A CB   1 
ATOM   544  C  CG   . ARG A 1 38  ? 10.22450  -16.89157 8.90684  1.000 12.96447 ? 61  ARG A CG   1 
ATOM   545  C  CD   . ARG A 1 38  ? 10.28857  -15.56496 8.17126  1.000 13.70353 ? 61  ARG A CD   1 
ATOM   546  N  NE   . ARG A 1 38  ? 10.88281  -15.70091 6.84898  1.000 14.62313 ? 61  ARG A NE   1 
ATOM   547  C  CZ   . ARG A 1 38  ? 12.18176  -15.84502 6.61275  1.000 15.96959 ? 61  ARG A CZ   1 
ATOM   548  N  NH1  . ARG A 1 38  ? 13.07457  -15.78820 7.58889  1.000 16.91222 ? 61  ARG A NH1  1 
ATOM   549  N  NH2  . ARG A 1 38  ? 12.59303  -16.05308 5.36362  1.000 18.02240 ? 61  ARG A NH2  1 
ATOM   550  H  H    . ARG A 1 38  ? 9.73352   -19.74319 10.21480 1.000 13.99922 ? 61  ARG A H    1 
ATOM   551  H  HA   . ARG A 1 38  ? 10.45675  -18.07117 11.29098 1.000 14.28989 ? 61  ARG A HA   1 
ATOM   552  H  HB2  . ARG A 1 38  ? 8.45586   -16.68659 9.88358  1.000 13.93411 ? 61  ARG A HB2  1 
ATOM   553  H  HB3  . ARG A 1 38  ? 9.66571   -15.97965 10.63319 1.000 13.93411 ? 61  ARG A HB3  1 
ATOM   554  H  HG2  . ARG A 1 38  ? 11.12685  -17.15318 9.14814  1.000 15.55737 ? 61  ARG A HG2  1 
ATOM   555  H  HG3  . ARG A 1 38  ? 9.83453   -17.55314 8.31426  1.000 15.55737 ? 61  ARG A HG3  1 
ATOM   556  H  HD2  . ARG A 1 38  ? 9.38997   -15.21558 8.06480  1.000 16.44424 ? 61  ARG A HD2  1 
ATOM   557  H  HD3  . ARG A 1 38  ? 10.82819  -14.94223 8.68305  1.000 16.44424 ? 61  ARG A HD3  1 
ATOM   558  H  HE   . ARG A 1 38  ? 10.35377  -15.68685 6.17111  1.000 17.54776 ? 61  ARG A HE   1 
ATOM   559  H  HH11 . ARG A 1 38  ? 12.81817  -15.65524 8.39894  1.000 20.29466 ? 61  ARG A HH11 1 
ATOM   560  H  HH12 . ARG A 1 38  ? 13.91086  -15.88426 7.41285  1.000 20.29466 ? 61  ARG A HH12 1 
ATOM   561  H  HH21 . ARG A 1 38  ? 12.02030  -16.09253 4.72328  1.000 21.62688 ? 61  ARG A HH21 1 
ATOM   562  H  HH22 . ARG A 1 38  ? 13.43140  -16.14803 5.19712  1.000 21.62688 ? 61  ARG A HH22 1 
ATOM   563  N  N    . ALA A 1 39  ? 8.45830   -18.83077 13.10734 1.000 11.79127 ? 62  ALA A N    1 
ATOM   564  C  CA   . ALA A 1 39  ? 7.52345   -18.73416 14.21528 1.000 11.31080 ? 62  ALA A CA   1 
ATOM   565  C  C    . ALA A 1 39  ? 8.13497   -18.10261 15.45873 1.000 11.54646 ? 62  ALA A C    1 
ATOM   566  O  O    . ALA A 1 39  ? 7.39824   -17.74255 16.37824 1.000 12.07043 ? 62  ALA A O    1 
ATOM   567  C  CB   . ALA A 1 39  ? 6.97053   -20.11579 14.55469 1.000 12.57027 ? 62  ALA A CB   1 
ATOM   568  H  H    . ALA A 1 39  ? 8.77288   -19.61898 12.96820 1.000 14.14952 ? 62  ALA A H    1 
ATOM   569  H  HA   . ALA A 1 39  ? 6.77792   -18.17648 13.94310 1.000 13.57297 ? 62  ALA A HA   1 
ATOM   570  H  HB1  . ALA A 1 39  ? 6.32323   -20.02943 15.27194 1.000 15.08432 ? 62  ALA A HB1  1 
ATOM   571  H  HB2  . ALA A 1 39  ? 6.54370   -20.48739 13.76689 1.000 15.08432 ? 62  ALA A HB2  1 
ATOM   572  H  HB3  . ALA A 1 39  ? 7.70146   -20.68811 14.83591 1.000 15.08432 ? 62  ALA A HB3  1 
ATOM   573  N  N    . ASP A 1 40  ? 9.45160   -17.93535 15.50210 1.000 11.99809 ? 63  ASP A N    1 
ATOM   574  C  CA   . ASP A 1 40  ? 10.10408  -17.23966 16.60033 1.000 12.69950 ? 63  ASP A CA   1 
ATOM   575  C  C    . ASP A 1 40  ? 10.54801  -15.83144 16.23861 1.000 12.47830 ? 63  ASP A C    1 
ATOM   576  O  O    . ASP A 1 40  ? 11.14231  -15.15307 17.08501 1.000 15.09504 ? 63  ASP A O    1 
ATOM   577  C  CB   . ASP A 1 40  ? 11.27305  -18.07343 17.10700 1.000 14.28378 ? 63  ASP A CB   1 
ATOM   578  C  CG   . ASP A 1 40  ? 10.81181  -19.36438 17.72171 1.000 16.93785 ? 63  ASP A CG   1 
ATOM   579  O  OD1  . ASP A 1 40  ? 9.89695   -19.30780 18.55789 1.000 17.38130 ? 63  ASP A OD1  1 
ATOM   580  O  OD2  . ASP A 1 40  ? 11.33880  -20.43162 17.34931 1.000 18.13960 ? 63  ASP A OD2  1 
ATOM   581  H  H    . ASP A 1 40  ? 9.99394   -18.22015 14.89848 1.000 14.39771 ? 63  ASP A H    1 
ATOM   582  H  HA   . ASP A 1 40  ? 9.47890   -17.14431 17.33582 1.000 15.23940 ? 63  ASP A HA   1 
ATOM   583  H  HB2  . ASP A 1 40  ? 11.86169  -18.28313 16.36509 1.000 17.14054 ? 63  ASP A HB2  1 
ATOM   584  H  HB3  . ASP A 1 40  ? 11.75579  -17.57076 17.78168 1.000 17.14054 ? 63  ASP A HB3  1 
ATOM   585  N  N    . GLU A 1 41  ? 10.26149  -15.36991 15.02290 1.000 11.69045 ? 64  GLU A N    1 
ATOM   586  C  CA   . GLU A 1 41  ? 10.54106  -13.98755 14.66300 1.000 11.24376 ? 64  GLU A CA   1 
ATOM   587  C  C    . GLU A 1 41  ? 9.42454   -13.07799 15.14857 1.000 10.90475 ? 64  GLU A C    1 
ATOM   588  O  O    . GLU A 1 41  ? 8.27370   -13.49679 15.29175 1.000 12.24757 ? 64  GLU A O    1 
ATOM   589  C  CB   . GLU A 1 41  ? 10.68656  -13.84293 13.14744 1.000 12.49605 ? 64  GLU A CB   1 
ATOM   590  C  CG   . GLU A 1 41  ? 11.82230  -14.69342 12.56903 1.000 13.92137 ? 64  GLU A CG   1 
ATOM   591  C  CD   . GLU A 1 41  ? 12.10511  -14.42548 11.11196 1.000 14.60091 ? 64  GLU A CD   1 
ATOM   592  O  OE1  . GLU A 1 41  ? 11.61449  -13.40461 10.60281 1.000 15.92550 ? 64  GLU A OE1  1 
ATOM   593  O  OE2  . GLU A 1 41  ? 12.82421  -15.23406 10.48341 1.000 15.52092 ? 64  GLU A OE2  1 
ATOM   594  H  H    . GLU A 1 41  ? 9.90679   -15.83676 14.39374 1.000 14.02854 ? 64  GLU A H    1 
ATOM   595  H  HA   . GLU A 1 41  ? 11.37333  -13.71130 15.07763 1.000 13.49251 ? 64  GLU A HA   1 
ATOM   596  H  HB2  . GLU A 1 41  ? 9.85929   -14.12116 12.72422 1.000 14.99526 ? 64  GLU A HB2  1 
ATOM   597  H  HB3  . GLU A 1 41  ? 10.87115  -12.91431 12.93652 1.000 14.99526 ? 64  GLU A HB3  1 
ATOM   598  H  HG2  . GLU A 1 41  ? 12.63446  -14.50851 13.06612 1.000 16.70564 ? 64  GLU A HG2  1 
ATOM   599  H  HG3  . GLU A 1 41  ? 11.58588  -15.63011 12.65635 1.000 16.70564 ? 64  GLU A HG3  1 
ATOM   600  N  N    . ARG A 1 42  ? 9.77177   -11.81529 15.37509 1.000 10.77949 ? 65  ARG A N    1 
ATOM   601  C  CA   . ARG A 1 42  ? 8.79960   -10.83143 15.79197 1.000 10.44376 ? 65  ARG A CA   1 
ATOM   602  C  C    . ARG A 1 42  ? 8.14027   -10.16689 14.59061 1.000 9.95851  ? 65  ARG A C    1 
ATOM   603  O  O    . ARG A 1 42  ? 8.79432   -9.88060  13.56964 1.000 10.95972 ? 65  ARG A O    1 
ATOM   604  C  CB   . ARG A 1 42  ? 9.43412   -9.76480  16.67211 1.000 11.39603 ? 65  ARG A CB   1 
ATOM   605  C  CG   . ARG A 1 42  ? 9.76576   -10.24450 18.06354 1.000 12.73568 ? 65  ARG A CG   1 
ATOM   606  C  CD   . ARG A 1 42  ? 10.29973  -9.13071  18.95145 1.000 13.42558 ? 65  ARG A CD   1 
ATOM   607  N  NE   . ARG A 1 42  ? 10.43092  -9.57095  20.33272 1.000 14.31835 ? 65  ARG A NE   1 
ATOM   608  C  CZ   . ARG A 1 42  ? 9.42081   -9.70927  21.18357 1.000 13.48968 ? 65  ARG A CZ   1 
ATOM   609  N  NH1  . ARG A 1 42  ? 8.19565   -9.30287  20.88905 1.000 11.78514 ? 65  ARG A NH1  1 
ATOM   610  N  NH2  . ARG A 1 42  ? 9.64887   -10.26488 22.36850 1.000 16.23235 ? 65  ARG A NH2  1 
ATOM   611  H  H    . ARG A 1 42  ? 10.57098  -11.50882 15.29179 1.000 12.93538 ? 65  ARG A H    1 
ATOM   612  H  HA   . ARG A 1 42  ? 8.11319   -11.28548 16.30537 1.000 12.53251 ? 65  ARG A HA   1 
ATOM   613  H  HB2  . ARG A 1 42  ? 10.25878  -9.46767  16.25673 1.000 13.67523 ? 65  ARG A HB2  1 
ATOM   614  H  HB3  . ARG A 1 42  ? 8.81724   -9.02076  16.75439 1.000 13.67523 ? 65  ARG A HB3  1 
ATOM   615  H  HG2  . ARG A 1 42  ? 8.96318   -10.59963 18.47664 1.000 15.28282 ? 65  ARG A HG2  1 
ATOM   616  H  HG3  . ARG A 1 42  ? 10.44393  -10.93578 18.00782 1.000 15.28282 ? 65  ARG A HG3  1 
ATOM   617  H  HD2  . ARG A 1 42  ? 11.17432  -8.85715  18.63341 1.000 16.11069 ? 65  ARG A HD2  1 
ATOM   618  H  HD3  . ARG A 1 42  ? 9.68767   -8.37858  18.92714 1.000 16.11069 ? 65  ARG A HD3  1 
ATOM   619  H  HE   . ARG A 1 42  ? 11.22077  -9.75501  20.61881 1.000 17.18202 ? 65  ARG A HE   1 
ATOM   620  H  HH11 . ARG A 1 42  ? 8.03547   -8.93678  20.12752 1.000 14.14217 ? 65  ARG A HH11 1 
ATOM   621  H  HH12 . ARG A 1 42  ? 7.56002   -9.40498  21.45926 1.000 14.14217 ? 65  ARG A HH12 1 
ATOM   622  H  HH21 . ARG A 1 42  ? 10.44112  -10.52855 22.57446 1.000 19.47881 ? 65  ARG A HH21 1 
ATOM   623  H  HH22 . ARG A 1 42  ? 9.00427   -10.36089 22.92963 1.000 19.47881 ? 65  ARG A HH22 1 
ATOM   624  N  N    . PHE A 1 43  ? 6.84389   -9.89590  14.74303 1.000 9.96377  ? 66  PHE A N    1 
ATOM   625  C  CA   . PHE A 1 43  ? 6.03048   -9.18090  13.77796 1.000 9.57993  ? 66  PHE A CA   1 
ATOM   626  C  C    . PHE A 1 43  ? 5.14690   -8.19981  14.52626 1.000 9.54567  ? 66  PHE A C    1 
ATOM   627  O  O    . PHE A 1 43  ? 4.65766   -8.50906  15.62683 1.000 9.48123  ? 66  PHE A O    1 
ATOM   628  C  CB   . PHE A 1 43  ? 5.08748   -10.11651 13.00371 1.000 9.64937  ? 66  PHE A CB   1 
ATOM   629  C  CG   . PHE A 1 43  ? 5.77879   -11.12631 12.13062 1.000 10.10105 ? 66  PHE A CG   1 
ATOM   630  C  CD1  . PHE A 1 43  ? 6.32591   -12.27682 12.67764 1.000 10.92477 ? 66  PHE A CD1  1 
ATOM   631  C  CD2  . PHE A 1 43  ? 5.81962   -10.95795 10.75410 1.000 11.10362 ? 66  PHE A CD2  1 
ATOM   632  C  CE1  . PHE A 1 43  ? 6.94132   -13.22500 11.88820 1.000 10.72951 ? 66  PHE A CE1  1 
ATOM   633  C  CE2  . PHE A 1 43  ? 6.40824   -11.90921 9.95638  1.000 11.57222 ? 66  PHE A CE2  1 
ATOM   634  C  CZ   . PHE A 1 43  ? 6.97992   -13.04764 10.53216 1.000 11.00479 ? 66  PHE A CZ   1 
ATOM   635  H  H    . PHE A 1 43  ? 6.39394   -10.13128 15.43711 1.000 11.95652 ? 66  PHE A H    1 
ATOM   636  H  HA   . PHE A 1 43  ? 6.62043   -8.72515  13.15737 1.000 11.49591 ? 66  PHE A HA   1 
ATOM   637  H  HB2  . PHE A 1 43  ? 4.54597   -10.60561 13.64282 1.000 11.57925 ? 66  PHE A HB2  1 
ATOM   638  H  HB3  . PHE A 1 43  ? 4.51944   -9.57681  12.43192 1.000 11.57925 ? 66  PHE A HB3  1 
ATOM   639  H  HD1  . PHE A 1 43  ? 6.27677   -12.41184 13.59647 1.000 13.10972 ? 66  PHE A HD1  1 
ATOM   640  H  HD2  . PHE A 1 43  ? 5.44683   -10.19766 10.36955 1.000 13.32435 ? 66  PHE A HD2  1 
ATOM   641  H  HE1  . PHE A 1 43  ? 7.32672   -13.97834 12.27401 1.000 12.87541 ? 66  PHE A HE1  1 
ATOM   642  H  HE2  . PHE A 1 43  ? 6.42635   -11.79579 9.03350  1.000 13.88666 ? 66  PHE A HE2  1 
ATOM   643  H  HZ   . PHE A 1 43  ? 7.38738   -13.68584 9.99219  1.000 13.20575 ? 66  PHE A HZ   1 
ATOM   644  N  N    . ALA A 1 44  ? 4.92421   -7.03330  13.92734 1.000 9.59023  ? 67  ALA A N    1 
ATOM   645  C  CA   . ALA A 1 44  ? 3.96217   -6.09425  14.47977 1.000 9.17910  ? 67  ALA A CA   1 
ATOM   646  C  C    . ALA A 1 44  ? 2.56278   -6.69911  14.45579 1.000 9.37771  ? 67  ALA A C    1 
ATOM   647  O  O    . ALA A 1 44  ? 2.05872   -7.09008  13.39968 1.000 10.28377 ? 67  ALA A O    1 
ATOM   648  C  CB   . ALA A 1 44  ? 3.99263   -4.80349  13.66663 1.000 10.58318 ? 67  ALA A CB   1 
ATOM   649  H  H    . ALA A 1 44  ? 5.31404   -6.76728  13.20841 1.000 11.50828 ? 67  ALA A H    1 
ATOM   650  H  HA   . ALA A 1 44  ? 4.19376   -5.89179  15.39970 1.000 11.01492 ? 67  ALA A HA   1 
ATOM   651  H  HB1  . ALA A 1 44  ? 3.36328   -4.17326  14.05087 1.000 12.69981 ? 67  ALA A HB1  1 
ATOM   652  H  HB2  . ALA A 1 44  ? 4.88911   -4.43407  13.69403 1.000 12.69981 ? 67  ALA A HB2  1 
ATOM   653  H  HB3  . ALA A 1 44  ? 3.74441   -5.00169  12.75012 1.000 12.69981 ? 67  ALA A HB3  1 
ATOM   654  N  N    . MET A 1 45  ? 1.93419   -6.76473  15.63054 1.000 8.44099  ? 68  MET A N    1 
ATOM   655  C  CA   . MET A 1 45  ? 0.63361   -7.40066  15.76039 1.000 8.25677  ? 68  MET A CA   1 
ATOM   656  C  C    . MET A 1 45  ? -0.49013  -6.62412  15.09715 1.000 8.51217  ? 68  MET A C    1 
ATOM   657  O  O    . MET A 1 45  ? -1.49364  -7.22655  14.66662 1.000 8.43649  ? 68  MET A O    1 
ATOM   658  C  CB   . MET A 1 45  ? 0.30088   -7.51805  17.25665 1.000 9.11826  ? 68  MET A CB   1 
ATOM   659  C  CG   . MET A 1 45  ? 1.11331   -8.54486  17.96843 1.000 9.94267  ? 68  MET A CG   1 
ATOM   660  S  SD   . MET A 1 45  ? 0.74019   -8.64769  19.72980 1.000 9.72759  ? 68  MET A SD   1 
ATOM   661  C  CE   . MET A 1 45  ? 1.53307   -7.17254  20.34104 1.000 10.35862 ? 68  MET A CE   1 
ATOM   662  H  H    . MET A 1 45  ? 2.24323   -6.44673  16.36740 1.000 10.12919 ? 68  MET A H    1 
ATOM   663  H  HA   . MET A 1 45  ? 0.69315   -8.27320  15.34082 1.000 9.90813  ? 68  MET A HA   1 
ATOM   664  H  HB2  . MET A 1 45  ? 0.46575   -6.66185  17.68167 1.000 10.94191 ? 68  MET A HB2  1 
ATOM   665  H  HB3  . MET A 1 45  ? -0.63350  -7.76082  17.35101 1.000 10.94191 ? 68  MET A HB3  1 
ATOM   666  H  HG2  . MET A 1 45  ? 0.93702   -9.41374  17.57490 1.000 11.93121 ? 68  MET A HG2  1 
ATOM   667  H  HG3  . MET A 1 45  ? 2.05292   -8.32280  17.87498 1.000 11.93121 ? 68  MET A HG3  1 
ATOM   668  H  HE1  . MET A 1 45  ? 1.37960   -7.10426  21.29639 1.000 12.43035 ? 68  MET A HE1  1 
ATOM   669  H  HE2  . MET A 1 45  ? 2.48478   -7.22825  20.16205 1.000 12.43035 ? 68  MET A HE2  1 
ATOM   670  H  HE3  . MET A 1 45  ? 1.15616   -6.40120  19.88951 1.000 12.43035 ? 68  MET A HE3  1 
ATOM   671  N  N    . CYS A 1 46  ? -0.38582  -5.30157  15.09184 1.000 8.88808  ? 69  CYS A N    1 
ATOM   672  C  CA   . CYS A 1 46  ? -1.48720  -4.44999  14.65773 1.000 8.15450  ? 69  CYS A CA   1 
ATOM   673  C  C    . CYS A 1 46  ? -2.75528  -4.86166  15.38954 1.000 8.62467  ? 69  CYS A C    1 
ATOM   674  O  O    . CYS A 1 46  ? -2.69241  -5.18361  16.58049 1.000 9.41891  ? 69  CYS A O    1 
ATOM   675  C  CB   . CYS A 1 46  ? -1.58200  -4.43766  13.13406 1.000 9.66753  ? 69  CYS A CB   1 
ATOM   676  S  SG   . CYS A 1 46  ? -0.04406  -3.83480  12.35290 1.000 10.51259 ? 69  CYS A SG   1 
ATOM   677  H  H    . CYS A 1 46  ? 0.31620   -4.86911  15.33627 1.000 10.66570 ? 69  CYS A H    1 
ATOM   678  H  HA   . CYS A 1 46  ? -1.34372  -3.51892  14.88889 1.000 9.78540  ? 69  CYS A HA   1 
ATOM   679  H  HB2  . CYS A 1 46  ? -1.74870  -5.33965  12.81860 1.000 11.60103 ? 69  CYS A HB2  1 
ATOM   680  H  HB3  . CYS A 1 46  ? -2.30774  -3.85281  12.86542 1.000 11.60103 ? 69  CYS A HB3  1 
ATOM   681  H  HG   . CYS A 1 46  ? -0.09826  -4.04227  11.17222 1.000 12.61511 ? 69  CYS A HG   1 
ATOM   682  N  N    . SER A 1 47  ? -3.89671  -4.87159  14.71388 1.000 8.82339  ? 70  SER A N    1 
ATOM   683  C  CA   . SER A 1 47  ? -5.13645  -5.07181  15.43899 1.000 8.51716  ? 70  SER A CA   1 
ATOM   684  C  C    . SER A 1 47  ? -5.30642  -6.47662  16.01075 1.000 9.42677  ? 70  SER A C    1 
ATOM   685  O  O    . SER A 1 47  ? -6.25892  -6.68220  16.77654 1.000 9.33526  ? 70  SER A O    1 
ATOM   686  C  CB   . SER A 1 47  ? -6.35567  -4.74966  14.58474 1.000 9.89693  ? 70  SER A CB   1 
ATOM   687  O  OG   . SER A 1 47  ? -6.44490  -3.37111  14.29993 1.000 10.59499 ? 70  SER A OG   1 
ATOM   688  H  H    . SER A 1 47  ? -3.97479  -4.76788  13.86374 1.000 10.58807 ? 70  SER A H    1 
ATOM   689  H  HA   . SER A 1 47  ? -5.11376  -4.44209  16.17644 1.000 10.22059 ? 70  SER A HA   1 
ATOM   690  H  HB2  . SER A 1 47  ? -6.28884  -5.23736  13.74893 1.000 11.87631 ? 70  SER A HB2  1 
ATOM   691  H  HB3  . SER A 1 47  ? -7.15363  -5.02151  15.06459 1.000 11.87631 ? 70  SER A HB3  1 
ATOM   692  N  N    . THR A 1 48  ? -4.41895  -7.42961  15.69374 1.000 9.27002  ? 71  THR A N    1 
ATOM   693  C  CA   . THR A 1 48  ? -4.53743  -8.72185  16.37046 1.000 8.74051  ? 71  THR A CA   1 
ATOM   694  C  C    . THR A 1 48  ? -4.30241  -8.58530  17.87142 1.000 8.71415  ? 71  THR A C    1 
ATOM   695  O  O    . THR A 1 48  ? -4.75247  -9.43715  18.63814 1.000 9.57862  ? 71  THR A O    1 
ATOM   696  C  CB   . THR A 1 48  ? -3.62732  -9.80343  15.76611 1.000 8.92605  ? 71  THR A CB   1 
ATOM   697  O  OG1  . THR A 1 48  ? -2.24126  -9.52418  16.02042 1.000 9.17151  ? 71  THR A OG1  1 
ATOM   698  C  CG2  . THR A 1 48  ? -3.88743  -9.97433  14.27538 1.000 9.27836  ? 71  THR A CG2  1 
ATOM   699  H  H    . THR A 1 48  ? -3.77868  -7.35508  15.12445 1.000 11.12402 ? 71  THR A H    1 
ATOM   700  H  HA   . THR A 1 48  ? -5.43836  -9.04938  16.22234 1.000 10.48861 ? 71  THR A HA   1 
ATOM   701  H  HB   . THR A 1 48  ? -3.83302  -10.64978 16.19305 1.000 10.71126 ? 71  THR A HB   1 
ATOM   702  H  HG1  . THR A 1 48  ? -1.97851  -8.89898  15.52476 1.000 11.00582 ? 71  THR A HG1  1 
ATOM   703  H  HG21 . THR A 1 48  ? -3.36530  -10.71542 13.93032 1.000 11.13403 ? 71  THR A HG21 1 
ATOM   704  H  HG22 . THR A 1 48  ? -4.82821  -10.15331 14.12114 1.000 11.13403 ? 71  THR A HG22 1 
ATOM   705  H  HG23 . THR A 1 48  ? -3.63877  -9.16596  13.80040 1.000 11.13403 ? 71  THR A HG23 1 
ATOM   706  N  N    . SER A 1 49  ? -3.63094  -7.51061  18.30453 1.000 8.85364  ? 72  SER A N    1 
ATOM   707  C  CA   . SER A 1 49  ? -3.41374  -7.24783  19.72538 1.000 8.84622  ? 72  SER A CA   1 
ATOM   708  C  C    . SER A 1 49  ? -4.70628  -6.93296  20.45538 1.000 8.83428  ? 72  SER A C    1 
ATOM   709  O  O    . SER A 1 49  ? -4.74097  -6.99638  21.68994 1.000 9.47080  ? 72  SER A O    1 
ATOM   710  C  CB   . SER A 1 49  ? -2.43759  -6.08429  19.88843 1.000 10.18620 ? 72  SER A CB   1 
ATOM   711  O  OG   . SER A 1 49  ? -2.97784  -4.87100  19.39177 1.000 9.71830  ? 72  SER A OG   1 
ATOM   712  H  H    . SER A 1 49  ? -3.28872  -6.91405  17.78819 1.000 10.62436 ? 72  SER A H    1 
ATOM   713  H  HA   . SER A 1 49  ? -3.02364  -8.03620  20.13426 1.000 10.61546 ? 72  SER A HA   1 
ATOM   714  H  HB2  . SER A 1 49  ? -2.23807  -5.97416  20.83128 1.000 12.22344 ? 72  SER A HB2  1 
ATOM   715  H  HB3  . SER A 1 49  ? -1.62520  -6.28760  19.39895 1.000 12.22344 ? 72  SER A HB3  1 
ATOM   716  H  HG   . SER A 1 49  ? -3.11375  -4.93410  18.56524 1.000 11.66196 ? 72  SER A HG   1 
ATOM   717  N  N    . LYS A 1 50  ? -5.78346  -6.61786  19.72838 1.000 8.78927  ? 73  LYS A N    1 
ATOM   718  C  CA   . LYS A 1 50  ? -7.06374  -6.33321  20.37651 1.000 9.19019  ? 73  LYS A CA   1 
ATOM   719  C  C    . LYS A 1 50  ? -7.58722  -7.54077  21.14288 1.000 8.86425  ? 73  LYS A C    1 
ATOM   720  O  O    . LYS A 1 50  ? -8.31576  -7.37636  22.12565 1.000 8.93104  ? 73  LYS A O    1 
ATOM   721  C  CB   . LYS A 1 50  ? -8.06688  -5.78160  19.35048 1.000 8.98441  ? 73  LYS A CB   1 
ATOM   722  C  CG   . LYS A 1 50  ? -7.67313  -4.38633  18.87629 1.000 9.66610  ? 73  LYS A CG   1 
ATOM   723  C  CD   . LYS A 1 50  ? -8.45792  -3.87372  17.66491 1.000 10.18790 ? 73  LYS A CD   1 
ATOM   724  C  CE   . LYS A 1 50  ? -7.99599  -2.45474  17.33463 1.000 10.69780 ? 73  LYS A CE   1 
ATOM   725  N  NZ   . LYS A 1 50  ? -8.17778  -2.00945  15.93454 1.000 10.83368 ? 73  LYS A NZ   1 
ATOM   726  H  H    . LYS A 1 50  ? -5.79848  -6.56308  18.87026 1.000 10.54712 ? 73  LYS A H    1 
ATOM   727  H  HA   . LYS A 1 50  ? -6.94851  -5.63126  21.03597 1.000 11.02823 ? 73  LYS A HA   1 
ATOM   728  H  HB2  . LYS A 1 50  ? -8.09311  -6.37008  18.57983 1.000 10.78129 ? 73  LYS A HB2  1 
ATOM   729  H  HB3  . LYS A 1 50  ? -8.94560  -5.72913  19.75790 1.000 10.78129 ? 73  LYS A HB3  1 
ATOM   730  H  HG2  . LYS A 1 50  ? -7.81910  -3.76079  19.60313 1.000 11.59931 ? 73  LYS A HG2  1 
ATOM   731  H  HG3  . LYS A 1 50  ? -6.73464  -4.39711  18.63129 1.000 11.59931 ? 73  LYS A HG3  1 
ATOM   732  H  HD2  . LYS A 1 50  ? -8.29316  -4.44503  16.89852 1.000 12.22547 ? 73  LYS A HD2  1 
ATOM   733  H  HD3  . LYS A 1 50  ? -9.40617  -3.85694  17.86845 1.000 12.22547 ? 73  LYS A HD3  1 
ATOM   734  H  HE2  . LYS A 1 50  ? -8.49214  -1.83778  17.89506 1.000 12.83736 ? 73  LYS A HE2  1 
ATOM   735  H  HE3  . LYS A 1 50  ? -7.04813  -2.39257  17.53111 1.000 12.83736 ? 73  LYS A HE3  1 
ATOM   736  H  HZ1  . LYS A 1 50  ? -7.73750  -2.55175  15.38303 1.000 13.00041 ? 73  LYS A HZ1  1 
ATOM   737  H  HZ2  . LYS A 1 50  ? -9.04182  -2.02020  15.72145 1.000 13.00041 ? 73  LYS A HZ2  1 
ATOM   738  H  HZ3  . LYS A 1 50  ? -7.86614  -1.18169  15.83549 1.000 13.00041 ? 73  LYS A HZ3  1 
ATOM   739  N  N    . VAL A 1 51  ? -7.22879  -8.75313  20.71244 1.000 8.98412  ? 74  VAL A N    1 
ATOM   740  C  CA   . VAL A 1 51  ? -7.61105  -9.94666  21.46233 1.000 9.40481  ? 74  VAL A CA   1 
ATOM   741  C  C    . VAL A 1 51  ? -7.03936  -9.89984  22.87298 1.000 9.03130  ? 74  VAL A C    1 
ATOM   742  O  O    . VAL A 1 51  ? -7.73246  -10.21270 23.84282 1.000 9.33482  ? 74  VAL A O    1 
ATOM   743  C  CB   . VAL A 1 51  ? -7.16980  -11.21826 20.72371 1.000 9.82711  ? 74  VAL A CB   1 
ATOM   744  C  CG1  . VAL A 1 51  ? -7.31745  -12.46920 21.58131 1.000 10.78859 ? 74  VAL A CG1  1 
ATOM   745  C  CG2  . VAL A 1 51  ? -7.97437  -11.38152 19.45174 1.000 10.46751 ? 74  VAL A CG2  1 
ATOM   746  H  H    . VAL A 1 51  ? -6.77161  -8.90768  20.00061 1.000 10.78095 ? 74  VAL A H    1 
ATOM   747  H  HA   . VAL A 1 51  ? -8.57866  -9.95950  21.52924 1.000 11.28577 ? 74  VAL A HA   1 
ATOM   748  H  HB   . VAL A 1 51  ? -6.22834  -11.12094 20.51138 1.000 11.79254 ? 74  VAL A HB   1 
ATOM   749  H  HG11 . VAL A 1 51  ? -7.06562  -13.24427 21.05525 1.000 12.94630 ? 74  VAL A HG11 1 
ATOM   750  H  HG12 . VAL A 1 51  ? -6.73750  -12.39193 22.35500 1.000 12.94630 ? 74  VAL A HG12 1 
ATOM   751  H  HG13 . VAL A 1 51  ? -8.24101  -12.54912 21.86687 1.000 12.94630 ? 74  VAL A HG13 1 
ATOM   752  H  HG21 . VAL A 1 51  ? -7.66506  -12.17160 18.98163 1.000 12.56101 ? 74  VAL A HG21 1 
ATOM   753  H  HG22 . VAL A 1 51  ? -8.91176  -11.47901 19.68132 1.000 12.56101 ? 74  VAL A HG22 1 
ATOM   754  H  HG23 . VAL A 1 51  ? -7.84981  -10.59613 18.89627 1.000 12.56101 ? 74  VAL A HG23 1 
ATOM   755  N  N    A MET A 1 52  ? -5.75040  -9.55671  23.00626 0.470 9.77128  ? 75  MET A N    1 
ATOM   756  N  N    B MET A 1 52  ? -5.76389  -9.51674  23.00778 0.530 9.33931  ? 75  MET A N    1 
ATOM   757  C  CA   A MET A 1 52  ? -5.13178  -9.54523  24.33213 0.470 10.06672 ? 75  MET A CA   1 
ATOM   758  C  CA   B MET A 1 52  ? -5.10620  -9.51474  24.31307 0.530 9.05538  ? 75  MET A CA   1 
ATOM   759  C  C    A MET A 1 52  ? -5.73974  -8.45473  25.20708 0.470 9.67956  ? 75  MET A C    1 
ATOM   760  C  C    B MET A 1 52  ? -5.64216  -8.41568  25.21232 0.530 9.43670  ? 75  MET A C    1 
ATOM   761  O  O    A MET A 1 52  ? -5.99309  -8.68067  26.39449 0.470 10.03950 ? 75  MET A O    1 
ATOM   762  O  O    B MET A 1 52  ? -5.72266  -8.59914  26.42970 0.530 10.42512 ? 75  MET A O    1 
ATOM   763  C  CB   A MET A 1 52  ? -3.60796  -9.40705  24.24149 0.470 10.69847 ? 75  MET A CB   1 
ATOM   764  C  CB   B MET A 1 52  ? -3.59845  -9.38976  24.13912 0.530 9.03380  ? 75  MET A CB   1 
ATOM   765  C  CG   A MET A 1 52  ? -2.85251  -9.85182  25.51477 0.470 12.01694 ? 75  MET A CG   1 
ATOM   766  C  CG   B MET A 1 52  ? -2.98583  -10.64528 23.60032 0.530 10.49742 ? 75  MET A CG   1 
ATOM   767  S  SD   A MET A 1 52  ? -2.71274  -11.65946 25.66115 0.470 13.92317 ? 75  MET A SD   1 
ATOM   768  S  SD   B MET A 1 52  ? -3.21128  -11.99725 24.76212 0.530 11.26018 ? 75  MET A SD   1 
ATOM   769  C  CE   A MET A 1 52  ? -1.37543  -11.99822 24.53121 0.470 13.55615 ? 75  MET A CE   1 
ATOM   770  C  CE   B MET A 1 52  ? -2.10504  -11.53086 26.08993 0.530 11.30505 ? 75  MET A CE   1 
ATOM   771  H  H    A MET A 1 52  ? -5.22827  -9.33279  22.36063 0.470 11.72554 ? 75  MET A H    1 
ATOM   772  H  H    B MET A 1 52  ? -5.26141  -9.25504  22.36076 0.530 11.20717 ? 75  MET A H    1 
ATOM   773  H  HA   A MET A 1 52  ? -5.29584  -10.40675 24.74658 0.470 12.08006 ? 75  MET A HA   1 
ATOM   774  H  HA   B MET A 1 52  ? -5.27664  -10.36615 24.74544 0.530 10.86646 ? 75  MET A HA   1 
ATOM   775  H  HB2  A MET A 1 52  ? -3.29061  -9.95342  23.50551 0.470 12.83816 ? 75  MET A HB2  1 
ATOM   776  H  HB2  B MET A 1 52  ? -3.40873  -8.66938  23.51785 0.530 10.84056 ? 75  MET A HB2  1 
ATOM   777  H  HB3  A MET A 1 52  ? -3.39041  -8.47548  24.08098 0.470 12.83816 ? 75  MET A HB3  1 
ATOM   778  H  HB3  B MET A 1 52  ? -3.19369  -9.20055  25.00009 0.530 10.84056 ? 75  MET A HB3  1 
ATOM   779  H  HG2  A MET A 1 52  ? -1.95557  -9.48306  25.49430 0.470 14.42033 ? 75  MET A HG2  1 
ATOM   780  H  HG2  B MET A 1 52  ? -3.41274  -10.88200 22.76210 0.530 12.59690 ? 75  MET A HG2  1 
ATOM   781  H  HG3  A MET A 1 52  ? -3.32811  -9.52441  26.29420 0.470 14.42033 ? 75  MET A HG3  1 
ATOM   782  H  HG3  B MET A 1 52  ? -2.03529  -10.51025 23.46199 0.530 12.59690 ? 75  MET A HG3  1 
ATOM   783  H  HE1  A MET A 1 52  ? -0.58543  -12.23897 25.03998 0.470 16.26738 ? 75  MET A HE1  1 
ATOM   784  H  HE1  B MET A 1 52  ? -2.27343  -12.10117 26.85629 0.530 13.56606 ? 75  MET A HE1  1 
ATOM   785  H  HE2  A MET A 1 52  ? -1.63099  -12.73177 23.95027 0.470 16.26738 ? 75  MET A HE2  1 
ATOM   786  H  HE2  B MET A 1 52  ? -1.18883  -11.64060 25.79090 0.530 13.56606 ? 75  MET A HE2  1 
ATOM   787  H  HE3  A MET A 1 52  ? -1.19937  -11.20389 24.00306 0.470 16.26738 ? 75  MET A HE3  1 
ATOM   788  H  HE3  B MET A 1 52  ? -2.26738  -10.60397 26.32536 0.530 13.56606 ? 75  MET A HE3  1 
ATOM   789  N  N    . ALA A 1 53  ? -6.00205  -7.27298  24.64126 1.000 9.56340  ? 76  ALA A N    1 
ATOM   790  C  CA   . ALA A 1 53  ? -6.60400  -6.20078  25.43523 1.000 10.00130 ? 76  ALA A CA   1 
ATOM   791  C  C    . ALA A 1 53  ? -7.97861  -6.60907  25.94453 1.000 9.90314  ? 76  ALA A C    1 
ATOM   792  O  O    . ALA A 1 53  ? -8.31415  -6.39604  27.11667 1.000 10.33552 ? 76  ALA A O    1 
ATOM   793  C  CB   . ALA A 1 53  ? -6.66944  -4.91526  24.61888 1.000 10.85416 ? 76  ALA A CB   1 
ATOM   794  H  H    A ALA A 1 53  ? -5.84495  -7.07170  23.82004 0.470 11.47608 ? 76  ALA A H    1 
ATOM   795  H  H    B ALA A 1 53  ? -5.91142  -7.09095  23.80565 0.530 11.47608 ? 76  ALA A H    1 
ATOM   796  H  HA   . ALA A 1 53  ? -6.04408  -6.02406  26.20735 1.000 12.00156 ? 76  ALA A HA   1 
ATOM   797  H  HB1  . ALA A 1 53  ? -7.11327  -4.23044  25.14323 1.000 13.02499 ? 76  ALA A HB1  1 
ATOM   798  H  HB2  . ALA A 1 53  ? -5.76724  -4.63280  24.40172 1.000 13.02499 ? 76  ALA A HB2  1 
ATOM   799  H  HB3  . ALA A 1 53  ? -7.16848  -5.08351  23.80430 1.000 13.02499 ? 76  ALA A HB3  1 
ATOM   800  N  N    . ALA A 1 54  ? -8.81174  -7.17110  25.06937 1.000 9.37861  ? 77  ALA A N    1 
ATOM   801  C  CA   . ALA A 1 54  ? -10.12552 -7.62720  25.50698 1.000 9.61205  ? 77  ALA A CA   1 
ATOM   802  C  C    . ALA A 1 54  ? -10.00670 -8.74542  26.52916 1.000 9.98286  ? 77  ALA A C    1 
ATOM   803  O  O    . ALA A 1 54  ? -10.75574 -8.77723  27.51359 1.000 10.83818 ? 77  ALA A O    1 
ATOM   804  C  CB   . ALA A 1 54  ? -10.93982 -8.08825  24.31108 1.000 10.59823 ? 77  ALA A CB   1 
ATOM   805  H  H    . ALA A 1 54  ? -8.64332  -7.29671  24.23543 1.000 11.25433 ? 77  ALA A H    1 
ATOM   806  H  HA   . ALA A 1 54  ? -10.59138 -6.88521  25.92331 1.000 11.53446 ? 77  ALA A HA   1 
ATOM   807  H  HB1  . ALA A 1 54  ? -11.81662 -8.36990  24.61569 1.000 12.71787 ? 77  ALA A HB1  1 
ATOM   808  H  HB2  . ALA A 1 54  ? -11.02764 -7.35176  23.68595 1.000 12.71787 ? 77  ALA A HB2  1 
ATOM   809  H  HB3  . ALA A 1 54  ? -10.48324 -8.83073  23.88545 1.000 12.71787 ? 77  ALA A HB3  1 
ATOM   810  N  N    . ALA A 1 55  ? -9.05868  -9.65999  26.32613 1.000 9.44021  ? 78  ALA A N    1 
ATOM   811  C  CA   . ALA A 1 55  ? -8.87931  -10.74693 27.28214 1.000 9.50367  ? 78  ALA A CA   1 
ATOM   812  C  C    . ALA A 1 55  ? -8.42576  -10.23111 28.64891 1.000 9.59882  ? 78  ALA A C    1 
ATOM   813  O  O    . ALA A 1 55  ? -8.82358  -10.77755 29.68882 1.000 9.83180  ? 78  ALA A O    1 
ATOM   814  C  CB   . ALA A 1 55  ? -7.88279  -11.76679 26.73346 1.000 10.15784 ? 78  ALA A CB   1 
ATOM   815  H  H    . ALA A 1 55  ? -8.51832  -9.67288  25.65721 1.000 11.32826 ? 78  ALA A H    1 
ATOM   816  H  HA   . ALA A 1 55  ? -9.73222  -11.19225 27.40517 1.000 11.40441 ? 78  ALA A HA   1 
ATOM   817  H  HB1  . ALA A 1 55  ? -7.76088  -12.47264 27.38753 1.000 12.18940 ? 78  ALA A HB1  1 
ATOM   818  H  HB2  . ALA A 1 55  ? -8.23241  -12.13744 25.90806 1.000 12.18940 ? 78  ALA A HB2  1 
ATOM   819  H  HB3  . ALA A 1 55  ? -7.03712  -11.32269 26.56455 1.000 12.18940 ? 78  ALA A HB3  1 
ATOM   820  N  N    . ALA A 1 56  ? -7.60585  -9.17391  28.67015 1.000 9.66968  ? 79  ALA A N    1 
ATOM   821  C  CA   . ALA A 1 56  ? -7.16609  -8.60908  29.93621 1.000 10.61429 ? 79  ALA A CA   1 
ATOM   822  C  C    . ALA A 1 56  ? -8.34711  -8.04559  30.70523 1.000 10.71183 ? 79  ALA A C    1 
ATOM   823  O  O    . ALA A 1 56  ? -8.43094  -8.20669  31.92638 1.000 12.26888 ? 79  ALA A O    1 
ATOM   824  C  CB   . ALA A 1 56  ? -6.11579  -7.53389  29.68724 1.000 12.77714 ? 79  ALA A CB   1 
ATOM   825  H  H    . ALA A 1 56  ? -7.29759  -8.77521  27.97329 1.000 11.60361 ? 79  ALA A H    1 
ATOM   826  H  HA   . ALA A 1 56  ? -6.75518  -9.30257  30.47577 1.000 12.73714 ? 79  ALA A HA   1 
ATOM   827  H  HB1  . ALA A 1 56  ? -5.84197  -7.15688  30.53800 1.000 15.33257 ? 79  ALA A HB1  1 
ATOM   828  H  HB2  . ALA A 1 56  ? -5.35281  -7.93476  29.24219 1.000 15.33257 ? 79  ALA A HB2  1 
ATOM   829  H  HB3  . ALA A 1 56  ? -6.49945  -6.84141  29.12672 1.000 15.33257 ? 79  ALA A HB3  1 
ATOM   830  N  N    . VAL A 1 57  ? -9.27758  -7.39126  30.01193 1.000 11.15225 ? 80  VAL A N    1 
ATOM   831  C  CA   . VAL A 1 57  ? -10.48338 -6.88857  30.65993 1.000 11.61668 ? 80  VAL A CA   1 
ATOM   832  C  C    . VAL A 1 57  ? -11.36363 -8.04066  31.12684 1.000 11.73670 ? 80  VAL A C    1 
ATOM   833  O  O    . VAL A 1 57  ? -11.88301 -8.02781  32.24679 1.000 12.57669 ? 80  VAL A O    1 
ATOM   834  C  CB   . VAL A 1 57  ? -11.22720 -5.92407  29.71830 1.000 12.77474 ? 80  VAL A CB   1 
ATOM   835  C  CG1  . VAL A 1 57  ? -12.60582 -5.56711  30.26845 1.000 14.60157 ? 80  VAL A CG1  1 
ATOM   836  C  CG2  . VAL A 1 57  ? -10.41473 -4.65506  29.49469 1.000 14.28867 ? 80  VAL A CG2  1 
ATOM   837  H  H    . VAL A 1 57  ? -9.23434  -7.22628  29.16901 1.000 13.38270 ? 80  VAL A H    1 
ATOM   838  H  HA   . VAL A 1 57  ? -10.22734 -6.38721  31.44986 1.000 13.94002 ? 80  VAL A HA   1 
ATOM   839  H  HB   . VAL A 1 57  ? -11.34713 -6.37206  28.86635 1.000 15.32968 ? 80  VAL A HB   1 
ATOM   840  H  HG11 . VAL A 1 57  ? -12.97222 -4.83335  29.75054 1.000 17.52189 ? 80  VAL A HG11 1 
ATOM   841  H  HG12 . VAL A 1 57  ? -13.18426 -6.34262  30.19847 1.000 17.52189 ? 80  VAL A HG12 1 
ATOM   842  H  HG13 . VAL A 1 57  ? -12.51652 -5.30385  31.19776 1.000 17.52189 ? 80  VAL A HG13 1 
ATOM   843  H  HG21 . VAL A 1 57  ? -10.89915 -4.07257  28.88893 1.000 17.14640 ? 80  VAL A HG21 1 
ATOM   844  H  HG22 . VAL A 1 57  ? -10.28284 -4.21030  30.34656 1.000 17.14640 ? 80  VAL A HG22 1 
ATOM   845  H  HG23 . VAL A 1 57  ? -9.55689  -4.89306  29.10949 1.000 17.14640 ? 80  VAL A HG23 1 
ATOM   846  N  N    . LEU A 1 58  ? -11.50168 -9.08078  30.30321 1.000 11.86482 ? 81  LEU A N    1 
ATOM   847  C  CA   . LEU A 1 58  ? -12.28167 -10.23487 30.72693 1.000 11.36169 ? 81  LEU A CA   1 
ATOM   848  C  C    . LEU A 1 58  ? -11.68397 -10.85626 31.98231 1.000 11.57655 ? 81  LEU A C    1 
ATOM   849  O  O    . LEU A 1 58  ? -12.41526 -11.25322 32.89775 1.000 12.56658 ? 81  LEU A O    1 
ATOM   850  C  CB   . LEU A 1 58  ? -12.35129 -11.26980 29.60183 1.000 11.34116 ? 81  LEU A CB   1 
ATOM   851  C  CG   . LEU A 1 58  ? -13.34172 -10.98688 28.47078 1.000 11.66266 ? 81  LEU A CG   1 
ATOM   852  C  CD1  . LEU A 1 58  ? -13.08123 -11.93946 27.34240 1.000 12.60072 ? 81  LEU A CD1  1 
ATOM   853  C  CD2  . LEU A 1 58  ? -14.75392 -11.12284 28.99141 1.000 13.56022 ? 81  LEU A CD2  1 
ATOM   854  H  H    . LEU A 1 58  ? -11.16185 -9.13907  29.51535 1.000 14.23779 ? 81  LEU A H    1 
ATOM   855  H  HA   . LEU A 1 58  ? -13.18720 -9.94825  30.92386 1.000 13.63402 ? 81  LEU A HA   1 
ATOM   856  H  HB2  . LEU A 1 58  ? -11.47107 -11.33522 29.19954 1.000 13.60939 ? 81  LEU A HB2  1 
ATOM   857  H  HB3  . LEU A 1 58  ? -12.60152 -12.12153 29.99276 1.000 13.60939 ? 81  LEU A HB3  1 
ATOM   858  H  HG   . LEU A 1 58  ? -13.23595 -10.08304 28.13495 1.000 13.99519 ? 81  LEU A HG   1 
ATOM   859  H  HD11 . LEU A 1 58  ? -13.67728 -11.72827 26.60686 1.000 15.12086 ? 81  LEU A HD11 1 
ATOM   860  H  HD12 . LEU A 1 58  ? -12.15863 -11.84688 27.05756 1.000 15.12086 ? 81  LEU A HD12 1 
ATOM   861  H  HD13 . LEU A 1 58  ? -13.24321 -12.84507 27.64986 1.000 15.12086 ? 81  LEU A HD13 1 
ATOM   862  H  HD21 . LEU A 1 58  ? -15.37558 -10.93436 28.27105 1.000 16.27226 ? 81  LEU A HD21 1 
ATOM   863  H  HD22 . LEU A 1 58  ? -14.88585 -12.02813 29.31380 1.000 16.27226 ? 81  LEU A HD22 1 
ATOM   864  H  HD23 . LEU A 1 58  ? -14.88563 -10.49127 29.71574 1.000 16.27226 ? 81  LEU A HD23 1 
ATOM   865  N  N    . LYS A 1 59  ? -10.35831 -10.96707 32.03403 1.000 11.60695 ? 82  LYS A N    1 
ATOM   866  C  CA   . LYS A 1 59  ? -9.71732  -11.52956 33.21305 1.000 12.36680 ? 82  LYS A CA   1 
ATOM   867  C  C    . LYS A 1 59  ? -10.01414 -10.69422 34.45174 1.000 13.79514 ? 82  LYS A C    1 
ATOM   868  O  O    . LYS A 1 59  ? -10.33853 -11.23519 35.51936 1.000 15.82124 ? 82  LYS A O    1 
ATOM   869  C  CB   . LYS A 1 59  ? -8.21488  -11.65581 32.96926 1.000 14.36008 ? 82  LYS A CB   1 
ATOM   870  C  CG   . LYS A 1 59  ? -7.45033  -12.22716 34.13551 1.000 17.70260 ? 82  LYS A CG   1 
ATOM   871  C  CD   . LYS A 1 59  ? -7.68415  -13.69318 34.33315 1.000 23.23198 ? 82  LYS A CD   1 
ATOM   872  C  CE   . LYS A 1 59  ? -6.77797  -14.20634 35.44248 1.000 26.76153 ? 82  LYS A CE   1 
ATOM   873  N  NZ   . LYS A 1 59  ? -5.33813  -13.85809 35.19420 1.000 29.46350 ? 82  LYS A NZ   1 
ATOM   874  H  H    . LYS A 1 59  ? -9.81800  -10.72745 31.40934 1.000 13.92834 ? 82  LYS A H    1 
ATOM   875  H  HA   . LYS A 1 59  ? -10.06732 -12.41967 33.37465 1.000 14.84016 ? 82  LYS A HA   1 
ATOM   876  H  HB2  . LYS A 1 59  ? -8.07150  -12.23959 32.20798 1.000 17.23210 ? 82  LYS A HB2  1 
ATOM   877  H  HB3  . LYS A 1 59  ? -7.85494  -10.77436 32.78384 1.000 17.23210 ? 82  LYS A HB3  1 
ATOM   878  H  HG2  . LYS A 1 59  ? -6.50127  -12.09480 33.98493 1.000 21.24312 ? 82  LYS A HG2  1 
ATOM   879  H  HG3  . LYS A 1 59  ? -7.72457  -11.77013 34.94595 1.000 21.24312 ? 82  LYS A HG3  1 
ATOM   880  H  HD2  . LYS A 1 59  ? -8.60769  -13.84785 34.58625 1.000 27.87838 ? 82  LYS A HD2  1 
ATOM   881  H  HD3  . LYS A 1 59  ? -7.47974  -14.17220 33.51482 1.000 27.87838 ? 82  LYS A HD3  1 
ATOM   882  H  HE2  . LYS A 1 59  ? -7.04599  -13.80689 36.28481 1.000 32.11384 ? 82  LYS A HE2  1 
ATOM   883  H  HE3  . LYS A 1 59  ? -6.85202  -15.17209 35.49485 1.000 32.11384 ? 82  LYS A HE3  1 
ATOM   884  H  HZ1  . LYS A 1 59  ? -5.10401  -14.10050 34.37047 1.000 35.35620 ? 82  LYS A HZ1  1 
ATOM   885  H  HZ2  . LYS A 1 59  ? -5.21760  -12.98071 35.28234 1.000 35.35620 ? 82  LYS A HZ2  1 
ATOM   886  H  HZ3  . LYS A 1 59  ? -4.81741  -14.28135 35.77883 1.000 35.35620 ? 82  LYS A HZ3  1 
ATOM   887  N  N    . LYS A 1 60  ? -9.88453  -9.37391  34.33400 1.000 14.94756 ? 83  LYS A N    1 
ATOM   888  C  CA   . LYS A 1 60  ? -10.20395 -8.49837  35.46146 1.000 17.24883 ? 83  LYS A CA   1 
ATOM   889  C  C    . LYS A 1 60  ? -11.65008 -8.68773  35.91171 1.000 16.43807 ? 83  LYS A C    1 
ATOM   890  O  O    . LYS A 1 60  ? -11.93972 -8.64251  37.11064 1.000 18.34687 ? 83  LYS A O    1 
ATOM   891  C  CB   . LYS A 1 60  ? -9.91894  -7.04875  35.05648 1.000 21.45961 ? 83  LYS A CB   1 
ATOM   892  C  CG   . LYS A 1 60  ? -10.04746 -5.94308  36.11091 1.000 28.63350 ? 83  LYS A CG   1 
ATOM   893  C  CD   . LYS A 1 60  ? -9.83879  -4.58562  35.38760 1.000 34.41391 ? 83  LYS A CD   1 
ATOM   894  C  CE   . LYS A 1 60  ? -9.61902  -3.39541  36.32023 1.000 38.05577 ? 83  LYS A CE   1 
ATOM   895  N  NZ   . LYS A 1 60  ? -10.79290 -3.02089  37.16734 1.000 40.47988 ? 83  LYS A NZ   1 
ATOM   896  H  H    . LYS A 1 60  ? -9.61844  -8.96540  33.62554 1.000 17.93707 ? 83  LYS A H    1 
ATOM   897  H  HA   . LYS A 1 60  ? -9.64232  -8.71358  36.22248 1.000 20.69860 ? 83  LYS A HA   1 
ATOM   898  H  HB2  . LYS A 1 60  ? -9.00589  -7.01143  34.73115 1.000 25.75153 ? 83  LYS A HB2  1 
ATOM   899  H  HB3  . LYS A 1 60  ? -10.53492 -6.81919  34.34320 1.000 25.75153 ? 83  LYS A HB3  1 
ATOM   900  H  HG2  . LYS A 1 60  ? -10.93027 -5.96155  36.51241 1.000 34.36020 ? 83  LYS A HG2  1 
ATOM   901  H  HG3  . LYS A 1 60  ? -9.36914  -6.05047  36.79593 1.000 34.36020 ? 83  LYS A HG3  1 
ATOM   902  H  HD2  . LYS A 1 60  ? -9.05827  -4.65632  34.81603 1.000 41.29669 ? 83  LYS A HD2  1 
ATOM   903  H  HD3  . LYS A 1 60  ? -10.62549 -4.39578  34.85285 1.000 41.29669 ? 83  LYS A HD3  1 
ATOM   904  H  HE2  . LYS A 1 60  ? -8.88634  -3.60710  36.91963 1.000 45.66692 ? 83  LYS A HE2  1 
ATOM   905  H  HE3  . LYS A 1 60  ? -9.39346  -2.62128  35.78103 1.000 45.66692 ? 83  LYS A HE3  1 
ATOM   906  H  HZ1  . LYS A 1 60  ? -10.75500 -2.15626  37.37490 1.000 48.57586 ? 83  LYS A HZ1  1 
ATOM   907  H  HZ2  . LYS A 1 60  ? -11.54949 -3.17913  36.72617 1.000 48.57586 ? 83  LYS A HZ2  1 
ATOM   908  H  HZ3  . LYS A 1 60  ? -10.79112 -3.49854  37.91830 1.000 48.57586 ? 83  LYS A HZ3  1 
ATOM   909  N  N    . SER A 1 61  ? -12.56770 -8.95103  34.97139 1.000 15.61590 ? 84  SER A N    1 
ATOM   910  C  CA   . SER A 1 61  ? -13.98702 -9.09907  35.31431 1.000 17.20727 ? 84  SER A CA   1 
ATOM   911  C  C    . SER A 1 61  ? -14.27551 -10.36144 36.12654 1.000 18.20165 ? 84  SER A C    1 
ATOM   912  O  O    . SER A 1 61  ? -15.35247 -10.46210 36.72484 1.000 19.10321 ? 84  SER A O    1 
ATOM   913  C  CB   . SER A 1 61  ? -14.85135 -9.05902  34.03860 1.000 16.81650 ? 84  SER A CB   1 
ATOM   914  O  OG   . SER A 1 61  ? -14.83105 -10.29137 33.33105 1.000 17.89996 ? 84  SER A OG   1 
ATOM   915  H  H    . SER A 1 61  ? -12.39534 -9.04777  34.13441 1.000 18.73908 ? 84  SER A H    1 
ATOM   916  H  HA   . SER A 1 61  ? -14.24917 -8.34517  35.86551 1.000 20.64872 ? 84  SER A HA   1 
ATOM   917  H  HB2  . SER A 1 61  ? -15.76698 -8.86237  34.29128 1.000 20.17980 ? 84  SER A HB2  1 
ATOM   918  H  HB3  . SER A 1 61  ? -14.51099 -8.36213  33.45602 1.000 20.17980 ? 84  SER A HB3  1 
ATOM   919  H  HG   . SER A 1 61  ? -14.03889 -10.50901 33.15577 1.000 21.47995 ? 84  SER A HG   1 
ATOM   920  N  N    A GLU A 1 62  ? -13.34626 -11.31944 36.17289 0.665 18.21140 ? 85  GLU A N    1 
ATOM   921  N  N    B GLU A 1 62  ? -13.34474 -11.31837 36.17074 0.335 19.64525 ? 85  GLU A N    1 
ATOM   922  C  CA   A GLU A 1 62  ? -13.57764 -12.51178 36.97996 0.665 19.24977 ? 85  GLU A CA   1 
ATOM   923  C  CA   B GLU A 1 62  ? -13.57774 -12.51511 36.97057 0.335 21.59039 ? 85  GLU A CA   1 
ATOM   924  C  C    A GLU A 1 62  ? -13.69901 -12.17663 38.45027 0.665 22.32157 ? 85  GLU A C    1 
ATOM   925  C  C    B GLU A 1 62  ? -13.69251 -12.18457 38.44847 0.335 23.25063 ? 85  GLU A C    1 
ATOM   926  O  O    A GLU A 1 62  ? -14.45276 -12.83419 39.17554 0.665 24.33257 ? 85  GLU A O    1 
ATOM   927  O  O    B GLU A 1 62  ? -14.43547 -12.85153 39.17738 0.335 24.38662 ? 85  GLU A O    1 
ATOM   928  C  CB   A GLU A 1 62  ? -12.43605 -13.49881 36.78021 0.665 18.48868 ? 85  GLU A CB   1 
ATOM   929  C  CB   B GLU A 1 62  ? -12.44795 -13.51830 36.76266 0.335 22.38471 ? 85  GLU A CB   1 
ATOM   930  C  CG   A GLU A 1 62  ? -12.51600 -14.12875 35.44125 0.665 17.15714 ? 85  GLU A CG   1 
ATOM   931  C  CG   B GLU A 1 62  ? -12.30238 -13.95180 35.33098 0.335 22.87916 ? 85  GLU A CG   1 
ATOM   932  C  CD   A GLU A 1 62  ? -11.24990 -14.83615 35.02735 0.665 16.57649 ? 85  GLU A CD   1 
ATOM   933  C  CD   B GLU A 1 62  ? -11.45504 -15.19592 35.18229 0.335 23.62459 ? 85  GLU A CD   1 
ATOM   934  O  OE1  A GLU A 1 62  ? -10.40882 -15.17824 35.89747 0.665 16.54788 ? 85  GLU A OE1  1 
ATOM   935  O  OE1  B GLU A 1 62  ? -11.41436 -16.00702 36.13122 0.335 23.36479 ? 85  GLU A OE1  1 
ATOM   936  O  OE2  A GLU A 1 62  ? -11.11597 -15.04868 33.80569 0.665 15.82195 ? 85  GLU A OE2  1 
ATOM   937  O  OE2  B GLU A 1 62  ? -10.83161 -15.36335 34.11645 0.335 24.01132 ? 85  GLU A OE2  1 
ATOM   938  H  H    A GLU A 1 62  ? -12.59398 -11.30167 35.75654 0.665 21.85369 ? 85  GLU A H    1 
ATOM   939  H  H    B GLU A 1 62  ? -12.59103 -11.29729 35.75713 0.335 23.57430 ? 85  GLU A H    1 
ATOM   940  H  HA   A GLU A 1 62  ? -14.40566 -12.92499 36.68918 0.665 23.09973 ? 85  GLU A HA   1 
ATOM   941  H  HA   B GLU A 1 62  ? -14.40824 -12.92098 36.67656 0.335 25.90847 ? 85  GLU A HA   1 
ATOM   942  H  HB2  A GLU A 1 62  ? -11.58869 -13.03221 36.85205 0.665 22.18642 ? 85  GLU A HB2  1 
ATOM   943  H  HB2  B GLU A 1 62  ? -11.61159 -13.11186 37.03872 0.335 26.86165 ? 85  GLU A HB2  1 
ATOM   944  H  HB3  A GLU A 1 62  ? -12.48927 -14.19545 37.45309 0.665 22.18642 ? 85  GLU A HB3  1 
ATOM   945  H  HB3  B GLU A 1 62  ? -12.62572 -14.30764 37.29768 0.335 26.86165 ? 85  GLU A HB3  1 
ATOM   946  H  HG2  A GLU A 1 62  ? -13.23235 -14.78275 35.44591 0.665 20.58857 ? 85  GLU A HG2  1 
ATOM   947  H  HG2  B GLU A 1 62  ? -13.18118 -14.14161 34.96685 0.335 27.45500 ? 85  GLU A HG2  1 
ATOM   948  H  HG3  A GLU A 1 62  ? -12.69930 -13.44061 34.78264 0.665 20.58857 ? 85  GLU A HG3  1 
ATOM   949  H  HG3  B GLU A 1 62  ? -11.88081 -13.23909 34.82579 0.335 27.45500 ? 85  GLU A HG3  1 
ATOM   950  N  N    . SER A 1 63  ? -12.95360 -11.17856 38.91276 1.000 23.58628 ? 86  SER A N    1 
ATOM   951  C  CA   . SER A 1 63  ? -12.97758 -10.77530 40.30652 1.000 27.81696 ? 86  SER A CA   1 
ATOM   952  C  C    . SER A 1 63  ? -13.73897 -9.48047  40.53592 1.000 28.05951 ? 86  SER A C    1 
ATOM   953  O  O    . SER A 1 63  ? -13.88558 -9.06357  41.68756 1.000 28.63657 ? 86  SER A O    1 
ATOM   954  C  CB   . SER A 1 63  ? -11.54714 -10.65549 40.84243 1.000 31.81393 ? 86  SER A CB   1 
ATOM   955  O  OG   . SER A 1 63  ? -10.80366 -9.68855  40.13509 1.000 34.28422 ? 86  SER A OG   1 
ATOM   956  H  H    . SER A 1 63  ? -12.41697 -10.71260 38.42849 1.000 28.30354 ? 86  SER A H    1 
ATOM   957  H  HA   . SER A 1 63  ? -13.42386 -11.46383 40.82387 1.000 33.38035 ? 86  SER A HA   1 
ATOM   958  H  HB2  . SER A 1 63  ? -11.58443 -10.39835 41.77699 1.000 38.17672 ? 86  SER A HB2  1 
ATOM   959  H  HB3  . SER A 1 63  ? -11.10696 -11.51514 40.75219 1.000 38.17672 ? 86  SER A HB3  1 
ATOM   960  H  HG   . SER A 1 63  ? -11.14339 -8.92818  40.24475 1.000 41.14106 ? 86  SER A HG   1 
ATOM   961  N  N    . GLU A 1 64  ? -14.22948 -8.84393  39.47522 1.000 28.45732 ? 87  GLU A N    1 
ATOM   962  C  CA   . GLU A 1 64  ? -15.07520 -7.65254  39.57538 1.000 30.43044 ? 87  GLU A CA   1 
ATOM   963  C  C    . GLU A 1 64  ? -16.18293 -7.85824  38.55254 1.000 29.33986 ? 87  GLU A C    1 
ATOM   964  O  O    . GLU A 1 64  ? -16.15608 -7.28843  37.45559 1.000 25.80242 ? 87  GLU A O    1 
ATOM   965  C  CB   . GLU A 1 64  ? -14.28974 -6.38299  39.24685 1.000 36.06137 ? 87  GLU A CB   1 
ATOM   966  C  CG   . GLU A 1 64  ? -12.84495 -6.38946  39.69542 1.000 41.89457 ? 87  GLU A CG   1 
ATOM   967  C  CD   . GLU A 1 64  ? -12.02273 -5.33028  38.98277 1.000 46.29500 ? 87  GLU A CD   1 
ATOM   968  O  OE1  . GLU A 1 64  ? -12.61694 -4.45517  38.31054 1.000 47.45290 ? 87  GLU A OE1  1 
ATOM   969  O  OE2  . GLU A 1 64  ? -10.77936 -5.37914  39.08526 1.000 48.11011 ? 87  GLU A OE2  1 
ATOM   970  H  H    . GLU A 1 64  ? -14.08333 -9.08848  38.66378 1.000 34.14878 ? 87  GLU A H    1 
ATOM   971  H  HA   . GLU A 1 64  ? -15.43336 -7.55667  40.47172 1.000 36.51653 ? 87  GLU A HA   1 
ATOM   972  H  HB2  . GLU A 1 64  ? -14.29477 -6.25949  38.28476 1.000 43.27364 ? 87  GLU A HB2  1 
ATOM   973  H  HB3  . GLU A 1 64  ? -14.72514 -5.63218  39.67999 1.000 43.27364 ? 87  GLU A HB3  1 
ATOM   974  H  HG2  . GLU A 1 64  ? -12.80610 -6.21286  40.64842 1.000 50.27348 ? 87  GLU A HG2  1 
ATOM   975  H  HG3  . GLU A 1 64  ? -12.45500 -7.25642  39.50250 1.000 50.27348 ? 87  GLU A HG3  1 
ATOM   976  N  N    . PRO A 1 65  ? -17.17338 -8.69693  38.86519 1.000 32.30384 ? 88  PRO A N    1 
ATOM   977  C  CA   . PRO A 1 65  ? -18.09275 -9.15778  37.80923 1.000 34.17796 ? 88  PRO A CA   1 
ATOM   978  C  C    . PRO A 1 65  ? -19.03966 -8.09032  37.28232 1.000 34.18671 ? 88  PRO A C    1 
ATOM   979  O  O    . PRO A 1 65  ? -19.71736 -8.35053  36.28127 1.000 37.19654 ? 88  PRO A O    1 
ATOM   980  C  CB   . PRO A 1 65  ? -18.84617 -10.31753 38.47212 1.000 35.67092 ? 88  PRO A CB   1 
ATOM   981  C  CG   . PRO A 1 65  ? -18.80922 -9.99477  39.92965 1.000 36.33223 ? 88  PRO A CG   1 
ATOM   982  C  CD   . PRO A 1 65  ? -17.51961 -9.24414  40.19025 1.000 35.23641 ? 88  PRO A CD   1 
ATOM   983  H  HA   . PRO A 1 65  ? -17.58222 -9.50608  37.06160 1.000 41.01355 ? 88  PRO A HA   1 
ATOM   984  H  HB2  . PRO A 1 65  ? -19.75853 -10.35259 38.14459 1.000 42.80511 ? 88  PRO A HB2  1 
ATOM   985  H  HB3  . PRO A 1 65  ? -18.39513 -11.15633 38.28802 1.000 42.80511 ? 88  PRO A HB3  1 
ATOM   986  H  HG2  . PRO A 1 65  ? -19.57392 -9.44268  40.15621 1.000 43.59868 ? 88  PRO A HG2  1 
ATOM   987  H  HG3  . PRO A 1 65  ? -18.83106 -10.81815 40.44197 1.000 43.59868 ? 88  PRO A HG3  1 
ATOM   988  H  HD2  . PRO A 1 65  ? -17.65886 -8.53097  40.83282 1.000 42.28369 ? 88  PRO A HD2  1 
ATOM   989  H  HD3  . PRO A 1 65  ? -16.82776 -9.84572  40.50703 1.000 42.28369 ? 88  PRO A HD3  1 
ATOM   990  N  N    . ASN A 1 66  ? -19.11145 -6.91258  37.89754 1.000 29.28365 ? 89  ASN A N    1 
ATOM   991  C  CA   . ASN A 1 66  ? -19.84152 -5.79146  37.30854 1.000 27.64352 ? 89  ASN A CA   1 
ATOM   992  C  C    . ASN A 1 66  ? -18.97955 -4.97086  36.35219 1.000 21.81834 ? 89  ASN A C    1 
ATOM   993  O  O    . ASN A 1 66  ? -19.46810 -3.99989  35.76921 1.000 21.44479 ? 89  ASN A O    1 
ATOM   994  C  CB   . ASN A 1 66  ? -20.39644 -4.89554  38.41991 1.000 32.58933 ? 89  ASN A CB   1 
ATOM   995  C  CG   . ASN A 1 66  ? -21.59222 -4.07218  37.97014 1.000 38.14807 ? 89  ASN A CG   1 
ATOM   996  O  OD1  . ASN A 1 66  ? -22.38916 -4.50682  37.13993 1.000 39.37332 ? 89  ASN A OD1  1 
ATOM   997  N  ND2  . ASN A 1 66  ? -21.72441 -2.87343  38.52855 1.000 40.44732 ? 89  ASN A ND2  1 
ATOM   998  H  H    . ASN A 1 66  ? -18.74612 -6.73780  38.65621 1.000 35.14038 ? 89  ASN A H    1 
ATOM   999  H  HA   . ASN A 1 66  ? -20.59595 -6.13120  36.80227 1.000 33.17222 ? 89  ASN A HA   1 
ATOM   1000 H  HB2  . ASN A 1 66  ? -20.67781 -5.45164  39.16320 1.000 39.10720 ? 89  ASN A HB2  1 
ATOM   1001 H  HB3  . ASN A 1 66  ? -19.70192 -4.28285  38.70826 1.000 39.10720 ? 89  ASN A HB3  1 
ATOM   1002 H  HD21 . ASN A 1 66  ? -22.38404 -2.36718  38.30902 1.000 48.53679 ? 89  ASN A HD21 1 
ATOM   1003 H  HD22 . ASN A 1 66  ? -21.15032 -2.60398  39.10942 1.000 48.53679 ? 89  ASN A HD22 1 
ATOM   1004 N  N    . LEU A 1 67  ? -17.71930 -5.35116  36.16707 1.000 19.16139 ? 90  LEU A N    1 
ATOM   1005 C  CA   . LEU A 1 67  ? -16.80842 -4.55090  35.35688 1.000 17.47084 ? 90  LEU A CA   1 
ATOM   1006 C  C    . LEU A 1 67  ? -17.31713 -4.37178  33.93076 1.000 17.15445 ? 90  LEU A C    1 
ATOM   1007 O  O    . LEU A 1 67  ? -17.19675 -3.28334  33.35097 1.000 16.89790 ? 90  LEU A O    1 
ATOM   1008 C  CB   . LEU A 1 67  ? -15.42957 -5.20547  35.35624 1.000 17.68456 ? 90  LEU A CB   1 
ATOM   1009 C  CG   . LEU A 1 67  ? -14.35951 -4.46153  34.56247 1.000 18.31009 ? 90  LEU A CG   1 
ATOM   1010 C  CD1  . LEU A 1 67  ? -14.04583 -3.13486  35.20767 1.000 18.10909 ? 90  LEU A CD1  1 
ATOM   1011 C  CD2  . LEU A 1 67  ? -13.11369 -5.32773  34.46875 1.000 19.56645 ? 90  LEU A CD2  1 
ATOM   1012 H  H    . LEU A 1 67  ? -17.36820 -6.06352  36.49702 1.000 22.99367 ? 90  LEU A H    1 
ATOM   1013 H  HA   . LEU A 1 67  ? -16.73684 -3.66632  35.74839 1.000 20.96501 ? 90  LEU A HA   1 
ATOM   1014 H  HB2  . LEU A 1 67  ? -15.12041 -5.26824  36.27351 1.000 21.22147 ? 90  LEU A HB2  1 
ATOM   1015 H  HB3  . LEU A 1 67  ? -15.51233 -6.09254  34.97261 1.000 21.22147 ? 90  LEU A HB3  1 
ATOM   1016 H  HG   . LEU A 1 67  ? -14.68043 -4.27783  33.66572 1.000 21.97211 ? 90  LEU A HG   1 
ATOM   1017 H  HD11 . LEU A 1 67  ? -14.02009 -2.44871  34.52251 1.000 21.73091 ? 90  LEU A HD11 1 
ATOM   1018 H  HD12 . LEU A 1 67  ? -14.73633 -2.92830  35.85686 1.000 21.73091 ? 90  LEU A HD12 1 
ATOM   1019 H  HD13 . LEU A 1 67  ? -13.18405 -3.19419  35.64892 1.000 21.73091 ? 90  LEU A HD13 1 
ATOM   1020 H  HD21 . LEU A 1 67  ? -12.47002 -4.89334  33.88746 1.000 23.47974 ? 90  LEU A HD21 1 
ATOM   1021 H  HD22 . LEU A 1 67  ? -12.73730 -5.43666  35.35609 1.000 23.47974 ? 90  LEU A HD22 1 
ATOM   1022 H  HD23 . LEU A 1 67  ? -13.35735 -6.19300  34.10429 1.000 23.47974 ? 90  LEU A HD23 1 
ATOM   1023 N  N    . LEU A 1 68  ? -17.85636 -5.43014  33.32701 1.000 16.16668 ? 91  LEU A N    1 
ATOM   1024 C  CA   . LEU A 1 68  ? -18.26022 -5.33372  31.93044 1.000 16.69110 ? 91  LEU A CA   1 
ATOM   1025 C  C    . LEU A 1 68  ? -19.40533 -4.35036  31.72704 1.000 15.86669 ? 91  LEU A C    1 
ATOM   1026 O  O    . LEU A 1 68  ? -19.57956 -3.84819  30.61060 1.000 15.39130 ? 91  LEU A O    1 
ATOM   1027 C  CB   . LEU A 1 68  ? -18.60350 -6.71114  31.36659 1.000 17.94878 ? 91  LEU A CB   1 
ATOM   1028 C  CG   . LEU A 1 68  ? -17.46440 -7.73542  31.28020 1.000 21.44811 ? 91  LEU A CG   1 
ATOM   1029 C  CD1  . LEU A 1 68  ? -17.90415 -8.98678  30.51145 1.000 24.46117 ? 91  LEU A CD1  1 
ATOM   1030 C  CD2  . LEU A 1 68  ? -16.21704 -7.14437  30.65635 1.000 22.95433 ? 91  LEU A CD2  1 
ATOM   1031 H  H    . LEU A 1 68  ? -17.99471 -6.19466  33.69575 1.000 19.40001 ? 91  LEU A H    1 
ATOM   1032 H  HA   . LEU A 1 68  ? -17.50810 -5.00760  31.41194 1.000 20.02932 ? 91  LEU A HA   1 
ATOM   1033 H  HB2  . LEU A 1 68  ? -19.29118 -7.10044  31.92912 1.000 21.53854 ? 91  LEU A HB2  1 
ATOM   1034 H  HB3  . LEU A 1 68  ? -18.94182 -6.58850  30.46582 1.000 21.53854 ? 91  LEU A HB3  1 
ATOM   1035 H  HG   . LEU A 1 68  ? -17.23871 -7.99814  32.18626 1.000 25.73773 ? 91  LEU A HG   1 
ATOM   1036 H  HD11 . LEU A 1 68  ? -17.18291 -9.63527  30.52471 1.000 29.35340 ? 91  LEU A HD11 1 
ATOM   1037 H  HD12 . LEU A 1 68  ? -18.69164 -9.35911  30.93821 1.000 29.35340 ? 91  LEU A HD12 1 
ATOM   1038 H  HD13 . LEU A 1 68  ? -18.10965 -8.73928  29.59635 1.000 29.35340 ? 91  LEU A HD13 1 
ATOM   1039 H  HD21 . LEU A 1 68  ? -15.56636 -7.85094  30.52115 1.000 27.54520 ? 91  LEU A HD21 1 
ATOM   1040 H  HD22 . LEU A 1 68  ? -16.45000 -6.74190  29.80509 1.000 27.54520 ? 91  LEU A HD22 1 
ATOM   1041 H  HD23 . LEU A 1 68  ? -15.85459 -6.47059  31.25263 1.000 27.54520 ? 91  LEU A HD23 1 
ATOM   1042 N  N    . ASN A 1 69  ? -20.16494 -4.04337  32.77652 1.000 15.53471 ? 92  ASN A N    1 
ATOM   1043 C  CA   . ASN A 1 69  ? -21.23764 -3.07612  32.67590 1.000 15.68182 ? 92  ASN A CA   1 
ATOM   1044 C  C    . ASN A 1 69  ? -20.79012 -1.64760  32.92812 1.000 16.23603 ? 92  ASN A C    1 
ATOM   1045 O  O    . ASN A 1 69  ? -21.61011 -0.73869  32.78095 1.000 16.56141 ? 92  ASN A O    1 
ATOM   1046 C  CB   . ASN A 1 69  ? -22.34239 -3.40502  33.69179 1.000 18.02809 ? 92  ASN A CB   1 
ATOM   1047 C  CG   . ASN A 1 69  ? -23.02605 -4.71665  33.40208 1.000 21.35889 ? 92  ASN A CG   1 
ATOM   1048 O  OD1  . ASN A 1 69  ? -23.23528 -5.06999  32.24269 1.000 22.75685 ? 92  ASN A OD1  1 
ATOM   1049 N  ND2  . ASN A 1 69  ? -23.38526 -5.44300  34.45140 1.000 23.97902 ? 92  ASN A ND2  1 
ATOM   1050 H  H    . ASN A 1 69  ? -20.07303 -4.38734  33.55936 1.000 18.64166 ? 92  ASN A H    1 
ATOM   1051 H  HA   . ASN A 1 69  ? -21.60181 -3.13166  31.77857 1.000 18.81818 ? 92  ASN A HA   1 
ATOM   1052 H  HB2  . ASN A 1 69  ? -21.95150 -3.45937  34.57788 1.000 21.63371 ? 92  ASN A HB2  1 
ATOM   1053 H  HB3  . ASN A 1 69  ? -23.01328 -2.70487  33.66752 1.000 21.63371 ? 92  ASN A HB3  1 
ATOM   1054 H  HD21 . ASN A 1 69  ? -23.77855 -6.19915  34.33664 1.000 28.77482 ? 92  ASN A HD21 1 
ATOM   1055 H  HD22 . ASN A 1 69  ? -23.22499 -5.15802  35.24682 1.000 28.77482 ? 92  ASN A HD22 1 
ATOM   1056 N  N    . GLN A 1 70  ? -19.53761 -1.43244  33.33748 1.000 15.95481 ? 93  GLN A N    1 
ATOM   1057 C  CA   . GLN A 1 70  ? -19.05841 -0.08610  33.61177 1.000 16.74849 ? 93  GLN A CA   1 
ATOM   1058 C  C    . GLN A 1 70  ? -19.13193 0.75777   32.34458 1.000 14.93860 ? 93  GLN A C    1 
ATOM   1059 O  O    . GLN A 1 70  ? -18.74540 0.30741   31.25846 1.000 15.78505 ? 93  GLN A O    1 
ATOM   1060 C  CB   . GLN A 1 70  ? -17.62239 -0.13819  34.13262 1.000 18.68887 ? 93  GLN A CB   1 
ATOM   1061 C  CG   . GLN A 1 70  ? -17.06037 1.18795   34.58941 1.000 24.52124 ? 93  GLN A CG   1 
ATOM   1062 C  CD   . GLN A 1 70  ? -15.63588 1.07018   35.12209 1.000 28.92754 ? 93  GLN A CD   1 
ATOM   1063 O  OE1  . GLN A 1 70  ? -15.27785 0.08543   35.77197 1.000 31.13730 ? 93  GLN A OE1  1 
ATOM   1064 N  NE2  . GLN A 1 70  ? -14.81884 2.08037   34.84501 1.000 30.37426 ? 93  GLN A NE2  1 
ATOM   1065 H  H    . GLN A 1 70  ? -18.95128 -2.04907  33.46233 1.000 19.14577 ? 93  GLN A H    1 
ATOM   1066 H  HA   . GLN A 1 70  ? -19.61154 0.32719   34.29305 1.000 20.09819 ? 93  GLN A HA   1 
ATOM   1067 H  HB2  . GLN A 1 70  ? -17.59238 -0.74324  34.89019 1.000 22.42664 ? 93  GLN A HB2  1 
ATOM   1068 H  HB3  . GLN A 1 70  ? -17.04992 -0.46747  33.42217 1.000 22.42664 ? 93  GLN A HB3  1 
ATOM   1069 H  HG2  . GLN A 1 70  ? -17.05068 1.80284   33.83928 1.000 29.42549 ? 93  GLN A HG2  1 
ATOM   1070 H  HG3  . GLN A 1 70  ? -17.61863 1.54037   35.30008 1.000 29.42549 ? 93  GLN A HG3  1 
ATOM   1071 H  HE21 . GLN A 1 70  ? -15.10387 2.75118   34.38854 1.000 36.44912 ? 93  GLN A HE21 1 
ATOM   1072 H  HE22 . GLN A 1 70  ? -14.00488 2.06352   35.12212 1.000 36.44912 ? 93  GLN A HE22 1 
ATOM   1073 N  N    . ARG A 1 71  ? -19.64891 1.97766   32.49086 1.000 16.44207 ? 94  ARG A N    1 
ATOM   1074 C  CA   . ARG A 1 71  ? -19.84911 2.89310   31.37643 1.000 16.35486 ? 94  ARG A CA   1 
ATOM   1075 C  C    . ARG A 1 71  ? -18.60728 3.76782   31.19210 1.000 15.33016 ? 94  ARG A C    1 
ATOM   1076 O  O    . ARG A 1 71  ? -18.03875 4.28820   32.16222 1.000 17.93757 ? 94  ARG A O    1 
ATOM   1077 C  CB   . ARG A 1 71  ? -21.04344 3.82613   31.61514 1.000 17.26028 ? 94  ARG A CB   1 
ATOM   1078 C  CG   . ARG A 1 71  ? -22.36987 3.20380   32.01502 1.000 17.85694 ? 94  ARG A CG   1 
ATOM   1079 C  CD   . ARG A 1 71  ? -22.92908 2.20460   31.02497 1.000 18.14342 ? 94  ARG A CD   1 
ATOM   1080 N  NE   . ARG A 1 71  ? -23.18128 2.75599   29.69885 1.000 16.31563 ? 94  ARG A NE   1 
ATOM   1081 C  CZ   . ARG A 1 71  ? -23.73717 2.06871   28.70684 1.000 15.68771 ? 94  ARG A CZ   1 
ATOM   1082 N  NH1  . ARG A 1 71  ? -24.14737 0.82889   28.87777 1.000 16.57331 ? 94  ARG A NH1  1 
ATOM   1083 N  NH2  . ARG A 1 71  ? -23.91603 2.65746   27.53031 1.000 16.11670 ? 94  ARG A NH2  1 
ATOM   1084 H  H    . ARG A 1 71  ? -19.89710 2.30384   33.24691 1.000 19.73048 ? 94  ARG A H    1 
ATOM   1085 H  HA   . ARG A 1 71  ? -20.01581 2.36590   30.57945 1.000 19.62583 ? 94  ARG A HA   1 
ATOM   1086 H  HB2  . ARG A 1 71  ? -20.80013 4.44037   32.32536 1.000 20.71233 ? 94  ARG A HB2  1 
ATOM   1087 H  HB3  . ARG A 1 71  ? -21.20359 4.31588   30.79332 1.000 20.71233 ? 94  ARG A HB3  1 
ATOM   1088 H  HG2  . ARG A 1 71  ? -22.25117 2.74088   32.85913 1.000 21.42832 ? 94  ARG A HG2  1 
ATOM   1089 H  HG3  . ARG A 1 71  ? -23.02518 3.91204   32.11434 1.000 21.42832 ? 94  ARG A HG3  1 
ATOM   1090 H  HD2  . ARG A 1 71  ? -22.29479 1.47755   30.92509 1.000 21.77210 ? 94  ARG A HD2  1 
ATOM   1091 H  HD3  . ARG A 1 71  ? -23.77103 1.86566   31.36722 1.000 21.77210 ? 94  ARG A HD3  1 
ATOM   1092 H  HE   . ARG A 1 71  ? -22.95736 3.57293   29.55027 1.000 19.57875 ? 94  ARG A HE   1 
ATOM   1093 H  HH11 . ARG A 1 71  ? -24.05774 0.44803   29.64361 1.000 19.88797 ? 94  ARG A HH11 1 
ATOM   1094 H  HH12 . ARG A 1 71  ? -24.50484 0.40018   28.22354 1.000 19.88797 ? 94  ARG A HH12 1 
ATOM   1095 H  HH21 . ARG A 1 71  ? -23.67301 3.47460   27.41701 1.000 19.34004 ? 94  ARG A HH21 1 
ATOM   1096 H  HH22 . ARG A 1 71  ? -24.27490 2.22168   26.88154 1.000 19.34004 ? 94  ARG A HH22 1 
ATOM   1097 N  N    . VAL A 1 72  ? -18.22286 3.96510   29.93412 1.000 14.74431 ? 95  VAL A N    1 
ATOM   1098 C  CA   . VAL A 1 72  ? -17.06231 4.74133   29.54541 1.000 14.47375 ? 95  VAL A CA   1 
ATOM   1099 C  C    . VAL A 1 72  ? -17.53151 5.83062   28.58742 1.000 13.11972 ? 95  VAL A C    1 
ATOM   1100 O  O    . VAL A 1 72  ? -18.18661 5.53933   27.58505 1.000 13.71549 ? 95  VAL A O    1 
ATOM   1101 C  CB   . VAL A 1 72  ? -16.04008 3.81122   28.86594 1.000 15.64006 ? 95  VAL A CB   1 
ATOM   1102 C  CG1  . VAL A 1 72  ? -14.86961 4.58146   28.37200 1.000 16.68582 ? 95  VAL A CG1  1 
ATOM   1103 C  CG2  . VAL A 1 72  ? -15.60858 2.68839   29.81019 1.000 16.64095 ? 95  VAL A CG2  1 
ATOM   1104 H  H    . VAL A 1 72  ? -18.64365 3.64036   29.25804 1.000 17.69318 ? 95  VAL A H    1 
ATOM   1105 H  HA   . VAL A 1 72  ? -16.65300 5.17544   30.31020 1.000 17.36850 ? 95  VAL A HA   1 
ATOM   1106 H  HB   . VAL A 1 72  ? -16.46346 3.39777   28.09737 1.000 18.76807 ? 95  VAL A HB   1 
ATOM   1107 H  HG11 . VAL A 1 72  ? -14.15458 3.96363   28.15307 1.000 20.02298 ? 95  VAL A HG11 1 
ATOM   1108 H  HG12 . VAL A 1 72  ? -15.13011 5.07945   27.58141 1.000 20.02298 ? 95  VAL A HG12 1 
ATOM   1109 H  HG13 . VAL A 1 72  ? -14.57774 5.19246   29.06654 1.000 20.02298 ? 95  VAL A HG13 1 
ATOM   1110 H  HG21 . VAL A 1 72  ? -14.92588 2.15440   29.37468 1.000 19.96914 ? 95  VAL A HG21 1 
ATOM   1111 H  HG22 . VAL A 1 72  ? -15.25379 3.07906   30.62407 1.000 19.96914 ? 95  VAL A HG22 1 
ATOM   1112 H  HG23 . VAL A 1 72  ? -16.37875 2.13607   30.01681 1.000 19.96914 ? 95  VAL A HG23 1 
ATOM   1113 N  N    . GLU A 1 73  ? -17.20239 7.07919   28.89730 1.000 15.59038 ? 96  GLU A N    1 
ATOM   1114 C  CA   . GLU A 1 73  ? -17.58858 8.18294   28.02339 1.000 15.96145 ? 96  GLU A CA   1 
ATOM   1115 C  C    . GLU A 1 73  ? -16.80492 8.14353   26.71193 1.000 14.38073 ? 96  GLU A C    1 
ATOM   1116 O  O    . GLU A 1 73  ? -15.59148 7.91498   26.71107 1.000 15.78827 ? 96  GLU A O    1 
ATOM   1117 C  CB   . GLU A 1 73  ? -17.31175 9.51877   28.70668 1.000 18.90560 ? 96  GLU A CB   1 
ATOM   1118 C  CG   . GLU A 1 73  ? -17.66139 10.75058  27.88271 1.000 24.68737 ? 96  GLU A CG   1 
ATOM   1119 C  CD   . GLU A 1 73  ? -19.15206 10.93476  27.64261 1.000 27.73382 ? 96  GLU A CD   1 
ATOM   1120 O  OE1  . GLU A 1 73  ? -19.96207 10.46004  28.47051 1.000 27.83088 ? 96  GLU A OE1  1 
ATOM   1121 O  OE2  . GLU A 1 73  ? -19.50752 11.55421  26.61413 1.000 28.26348 ? 96  GLU A OE2  1 
ATOM   1122 H  H    . GLU A 1 73  ? -16.76170 7.31259   29.59796 1.000 18.70845 ? 96  GLU A H    1 
ATOM   1123 H  HA   . GLU A 1 73  ? -18.53605 8.10570   27.83043 1.000 19.15374 ? 96  GLU A HA   1 
ATOM   1124 H  HB2  . GLU A 1 73  ? -17.83254 9.55875   29.52404 1.000 22.68672 ? 96  GLU A HB2  1 
ATOM   1125 H  HB3  . GLU A 1 73  ? -16.36531 9.56691   28.91364 1.000 22.68672 ? 96  GLU A HB3  1 
ATOM   1126 H  HG2  . GLU A 1 73  ? -17.33894 11.53797  28.34848 1.000 29.62485 ? 96  GLU A HG2  1 
ATOM   1127 H  HG3  . GLU A 1 73  ? -17.23069 10.67781  27.01663 1.000 29.62485 ? 96  GLU A HG3  1 
ATOM   1128 N  N    . ILE A 1 74  ? -17.50302 8.38219   25.59504 1.000 13.90919 ? 97  ILE A N    1 
ATOM   1129 C  CA   . ILE A 1 74  ? -16.90156 8.52498   24.27177 1.000 14.34014 ? 97  ILE A CA   1 
ATOM   1130 C  C    . ILE A 1 74  ? -17.00571 9.99860   23.90909 1.000 15.97317 ? 97  ILE A C    1 
ATOM   1131 O  O    . ILE A 1 74  ? -18.11079 10.53139  23.74930 1.000 17.21525 ? 97  ILE A O    1 
ATOM   1132 C  CB   . ILE A 1 74  ? -17.60558 7.66902   23.20718 1.000 14.79923 ? 97  ILE A CB   1 
ATOM   1133 C  CG1  . ILE A 1 74  ? -17.73952 6.22742   23.68252 1.000 15.70297 ? 97  ILE A CG1  1 
ATOM   1134 C  CG2  . ILE A 1 74  ? -16.86547 7.77331   21.85991 1.000 15.82102 ? 97  ILE A CG2  1 
ATOM   1135 C  CD1  . ILE A 1 74  ? -16.44913 5.52752   24.02348 1.000 15.99369 ? 97  ILE A CD1  1 
ATOM   1136 H  H    . ILE A 1 74  ? -18.35865 8.46787   25.58287 1.000 16.69103 ? 97  ILE A H    1 
ATOM   1137 H  HA   . ILE A 1 74  ? -15.97120 8.25392   24.31489 1.000 17.20817 ? 97  ILE A HA   1 
ATOM   1138 H  HB   . ILE A 1 74  ? -18.50367 8.00988   23.07249 1.000 17.75907 ? 97  ILE A HB   1 
ATOM   1139 H  HG12 . ILE A 1 74  ? -18.29000 6.22048   24.48116 1.000 18.84357 ? 97  ILE A HG12 1 
ATOM   1140 H  HG13 . ILE A 1 74  ? -18.16796 5.71409   22.97980 1.000 18.84357 ? 97  ILE A HG13 1 
ATOM   1141 H  HG21 . ILE A 1 74  ? -17.30844 7.20405   21.21136 1.000 18.98523 ? 97  ILE A HG21 1 
ATOM   1142 H  HG22 . ILE A 1 74  ? -16.88556 8.69527   21.55910 1.000 18.98523 ? 97  ILE A HG22 1 
ATOM   1143 H  HG23 . ILE A 1 74  ? -15.94731 7.48475   21.98080 1.000 18.98523 ? 97  ILE A HG23 1 
ATOM   1144 H  HD11 . ILE A 1 74  ? -16.64784 4.62556   24.31991 1.000 19.19243 ? 97  ILE A HD11 1 
ATOM   1145 H  HD12 . ILE A 1 74  ? -15.88667 5.49977   23.23369 1.000 19.19243 ? 97  ILE A HD12 1 
ATOM   1146 H  HD13 . ILE A 1 74  ? -16.00167 6.01726   24.73118 1.000 19.19243 ? 97  ILE A HD13 1 
ATOM   1147 N  N    . LYS A 1 75  ? -15.86834 10.65633  23.78920 1.000 15.86223 ? 98  LYS A N    1 
ATOM   1148 C  CA   . LYS A 1 75  ? -15.79903 12.07331  23.48526 1.000 17.38819 ? 98  LYS A CA   1 
ATOM   1149 C  C    . LYS A 1 75  ? -15.23112 12.27363  22.09096 1.000 16.00292 ? 98  LYS A C    1 
ATOM   1150 O  O    . LYS A 1 75  ? -14.54182 11.41491  21.55352 1.000 14.65379 ? 98  LYS A O    1 
ATOM   1151 C  CB   . LYS A 1 75  ? -14.88825 12.78214  24.49139 1.000 20.49284 ? 98  LYS A CB   1 
ATOM   1152 C  CG   . LYS A 1 75  ? -15.35407 12.68194  25.93472 1.000 23.28848 ? 98  LYS A CG   1 
ATOM   1153 C  CD   . LYS A 1 75  ? -14.30133 13.22124  26.91165 1.000 26.66460 ? 98  LYS A CD   1 
ATOM   1154 C  CE   . LYS A 1 75  ? -13.00520 12.40054  26.87097 1.000 29.07362 ? 98  LYS A CE   1 
ATOM   1155 N  NZ   . LYS A 1 75  ? -13.20871 10.93490  27.09785 1.000 29.96532 ? 98  LYS A NZ   1 
ATOM   1156 H  H    . LYS A 1 75  ? -15.09536 10.29115  23.88270 1.000 19.03467 ? 98  LYS A H    1 
ATOM   1157 H  HA   . LYS A 1 75  ? -16.68775 12.46008  23.52390 1.000 20.86583 ? 98  LYS A HA   1 
ATOM   1158 H  HB2  . LYS A 1 75  ? -14.00362 12.38755  24.43999 1.000 24.59141 ? 98  LYS A HB2  1 
ATOM   1159 H  HB3  . LYS A 1 75  ? -14.84556 13.72341  24.26100 1.000 24.59141 ? 98  LYS A HB3  1 
ATOM   1160 H  HG2  . LYS A 1 75  ? -16.16579 13.20120  26.04598 1.000 27.94618 ? 98  LYS A HG2  1 
ATOM   1161 H  HG3  . LYS A 1 75  ? -15.52263 11.75196  26.15294 1.000 27.94618 ? 98  LYS A HG3  1 
ATOM   1162 H  HD2  . LYS A 1 75  ? -14.08696 14.13753  26.67635 1.000 31.99752 ? 98  LYS A HD2  1 
ATOM   1163 H  HD3  . LYS A 1 75  ? -14.65470 13.18450  27.81425 1.000 31.99752 ? 98  LYS A HD3  1 
ATOM   1164 H  HE2  . LYS A 1 75  ? -12.59397 12.50976  25.99927 1.000 34.88835 ? 98  LYS A HE2  1 
ATOM   1165 H  HE3  . LYS A 1 75  ? -12.40802 12.72594  27.56263 1.000 34.88835 ? 98  LYS A HE3  1 
ATOM   1166 H  HZ1  . LYS A 1 75  ? -12.42184 10.52110  27.13899 1.000 35.95839 ? 98  LYS A HZ1  1 
ATOM   1167 H  HZ2  . LYS A 1 75  ? -13.64480 10.80289  27.86238 1.000 35.95839 ? 98  LYS A HZ2  1 
ATOM   1168 H  HZ3  . LYS A 1 75  ? -13.68365 10.58665  26.43058 1.000 35.95839 ? 98  LYS A HZ3  1 
ATOM   1169 N  N    . LYS A 1 76  ? -15.51135 13.43986  21.51160 1.000 17.45070 ? 99  LYS A N    1 
ATOM   1170 C  CA   . LYS A 1 76  ? -14.88124 13.77818  20.24273 1.000 18.03616 ? 99  LYS A CA   1 
ATOM   1171 C  C    . LYS A 1 76  ? -13.36911 13.66335  20.35040 1.000 16.71860 ? 99  LYS A C    1 
ATOM   1172 O  O    . LYS A 1 76  ? -12.69939 13.23640  19.40816 1.000 16.94613 ? 99  LYS A O    1 
ATOM   1173 C  CB   . LYS A 1 76  ? -15.28414 15.19307  19.82020 1.000 22.65835 ? 99  LYS A CB   1 
ATOM   1174 C  CG   . LYS A 1 76  ? -16.39967 15.21856  18.78354 1.000 30.61263 ? 99  LYS A CG   1 
ATOM   1175 C  CD   . LYS A 1 76  ? -16.74771 16.63902  18.35264 1.000 37.08442 ? 99  LYS A CD   1 
ATOM   1176 C  CE   . LYS A 1 76  ? -17.85717 16.65392  17.31038 1.000 41.92617 ? 99  LYS A CE   1 
ATOM   1177 N  NZ   . LYS A 1 76  ? -17.47638 15.93095  16.06444 1.000 44.59147 ? 99  LYS A NZ   1 
ATOM   1178 H  H    . LYS A 1 76  ? -16.04767 14.03474  21.82477 1.000 20.94083 ? 99  LYS A H    1 
ATOM   1179 H  HA   . LYS A 1 76  ? -15.18843 13.16503  19.55674 1.000 21.64339 ? 99  LYS A HA   1 
ATOM   1180 H  HB2  . LYS A 1 76  ? -15.59264 15.67767  20.60179 1.000 27.19002 ? 99  LYS A HB2  1 
ATOM   1181 H  HB3  . LYS A 1 76  ? -14.51167 15.63783  19.43760 1.000 27.19002 ? 99  LYS A HB3  1 
ATOM   1182 H  HG2  . LYS A 1 76  ? -16.11685 14.72477  17.99799 1.000 36.73516 ? 99  LYS A HG2  1 
ATOM   1183 H  HG3  . LYS A 1 76  ? -17.19588 14.81328  19.16129 1.000 36.73516 ? 99  LYS A HG3  1 
ATOM   1184 H  HD2  . LYS A 1 76  ? -17.04859 17.14368  19.12445 1.000 44.50131 ? 99  LYS A HD2  1 
ATOM   1185 H  HD3  . LYS A 1 76  ? -15.96268 17.05872  17.96730 1.000 44.50131 ? 99  LYS A HD3  1 
ATOM   1186 H  HE2  . LYS A 1 76  ? -18.64493 16.22440  17.67895 1.000 50.31141 ? 99  LYS A HE2  1 
ATOM   1187 H  HE3  . LYS A 1 76  ? -18.05974 17.57294  17.07529 1.000 50.31141 ? 99  LYS A HE3  1 
ATOM   1188 H  HZ1  . LYS A 1 76  ? -16.59438 15.96481  15.95033 1.000 53.50976 ? 99  LYS A HZ1  1 
ATOM   1189 H  HZ2  . LYS A 1 76  ? -17.72822 15.07899  16.11780 1.000 53.50976 ? 99  LYS A HZ2  1 
ATOM   1190 H  HZ3  . LYS A 1 76  ? -17.87316 16.30594  15.36156 1.000 53.50976 ? 99  LYS A HZ3  1 
ATOM   1191 N  N    . SER A 1 77  ? -12.81472 14.03469  21.50227 1.000 16.35988 ? 100 SER A N    1 
ATOM   1192 C  CA   . SER A 1 77  ? -11.37829 13.97919  21.72588 1.000 17.25912 ? 100 SER A CA   1 
ATOM   1193 C  C    . SER A 1 77  ? -10.83411 12.55994  21.73598 1.000 16.00576 ? 100 SER A C    1 
ATOM   1194 O  O    . SER A 1 77  ? -9.61274  12.38980  21.66217 1.000 16.74847 ? 100 SER A O    1 
ATOM   1195 C  CB   . SER A 1 77  ? -11.01993 14.68862  23.04147 1.000 18.84242 ? 100 SER A CB   1 
ATOM   1196 O  OG   . SER A 1 77  ? -11.67136 14.07738  24.14364 1.000 20.65357 ? 100 SER A OG   1 
ATOM   1197 H  H    . SER A 1 77  ? -13.25769 14.32670  22.17910 1.000 19.63185 ? 100 SER A H    1 
ATOM   1198 H  HA   . SER A 1 77  ? -10.93704 14.45484  21.00479 1.000 20.71094 ? 100 SER A HA   1 
ATOM   1199 H  HB2  . SER A 1 77  ? -10.06051 14.63834  23.17523 1.000 22.61090 ? 100 SER A HB2  1 
ATOM   1200 H  HB3  . SER A 1 77  ? -11.29894 15.61593  22.98541 1.000 22.61090 ? 100 SER A HB3  1 
ATOM   1201 H  HG   . SER A 1 77  ? -11.19480 13.45800  24.45162 1.000 24.78429 ? 100 SER A HG   1 
ATOM   1202 N  N    . ASP A 1 78  ? -11.69471 11.55442  21.84128 1.000 13.80130 ? 101 ASP A N    1 
ATOM   1203 C  CA   . ASP A 1 78  ? -11.25829 10.16965  21.80825 1.000 13.59872 ? 101 ASP A CA   1 
ATOM   1204 C  C    . ASP A 1 78  ? -11.12021 9.62829   20.39368 1.000 13.57643 ? 101 ASP A C    1 
ATOM   1205 O  O    . ASP A 1 78  ? -10.51149 8.57051   20.20558 1.000 13.67859 ? 101 ASP A O    1 
ATOM   1206 C  CB   . ASP A 1 78  ? -12.26514 9.28370   22.54088 1.000 13.27649 ? 101 ASP A CB   1 
ATOM   1207 C  CG   . ASP A 1 78  ? -12.29397 9.53671   24.01652 1.000 14.56132 ? 101 ASP A CG   1 
ATOM   1208 O  OD1  . ASP A 1 78  ? -11.20971 9.58172   24.60889 1.000 15.90785 ? 101 ASP A OD1  1 
ATOM   1209 O  OD2  . ASP A 1 78  ? -13.38898 9.66514   24.59861 1.000 15.72288 ? 101 ASP A OD2  1 
ATOM   1210 H  H    . ASP A 1 78  ? -12.54425 11.65123  21.93351 1.000 16.56156 ? 101 ASP A H    1 
ATOM   1211 H  HA   . ASP A 1 78  ? -10.39964 10.11221  22.25584 1.000 16.31846 ? 101 ASP A HA   1 
ATOM   1212 H  HB2  . ASP A 1 78  ? -13.15260 9.45669   22.18961 1.000 15.93179 ? 101 ASP A HB2  1 
ATOM   1213 H  HB3  . ASP A 1 78  ? -12.02834 8.35356   22.40070 1.000 15.93179 ? 101 ASP A HB3  1 
ATOM   1214 N  N    . LEU A 1 79  ? -11.70751 10.28275  19.39789 1.000 13.56862 ? 102 LEU A N    1 
ATOM   1215 C  CA   . LEU A 1 79  ? -11.71231 9.70785   18.06195 1.000 13.13254 ? 102 LEU A CA   1 
ATOM   1216 C  C    . LEU A 1 79  ? -10.29662 9.66728   17.51300 1.000 15.01364 ? 102 LEU A C    1 
ATOM   1217 O  O    . LEU A 1 79  ? -9.49821  10.57839  17.73285 1.000 18.36034 ? 102 LEU A O    1 
ATOM   1218 C  CB   . LEU A 1 79  ? -12.62081 10.49566  17.13602 1.000 13.92021 ? 102 LEU A CB   1 
ATOM   1219 C  CG   . LEU A 1 79  ? -14.08382 10.52510  17.55228 1.000 15.67567 ? 102 LEU A CG   1 
ATOM   1220 C  CD1  . LEU A 1 79  ? -14.86248 11.40952  16.59141 1.000 18.18047 ? 102 LEU A CD1  1 
ATOM   1221 C  CD2  . LEU A 1 79  ? -14.67826 9.14364   17.58717 1.000 16.84789 ? 102 LEU A CD2  1 
ATOM   1222 H  H    . LEU A 1 79  ? -12.10106 11.04408  19.46924 1.000 16.28234 ? 102 LEU A H    1 
ATOM   1223 H  HA   . LEU A 1 79  ? -12.05679 8.80182   18.09876 1.000 15.75904 ? 102 LEU A HA   1 
ATOM   1224 H  HB2  . LEU A 1 79  ? -12.30700 11.41297  17.10495 1.000 16.70426 ? 102 LEU A HB2  1 
ATOM   1225 H  HB3  . LEU A 1 79  ? -12.57621 10.09964  16.25167 1.000 16.70426 ? 102 LEU A HB3  1 
ATOM   1226 H  HG   . LEU A 1 79  ? -14.14891 10.88639  18.45013 1.000 18.81080 ? 102 LEU A HG   1 
ATOM   1227 H  HD11 . LEU A 1 79  ? -15.80900 11.33479  16.78994 1.000 21.81657 ? 102 LEU A HD11 1 
ATOM   1228 H  HD12 . LEU A 1 79  ? -14.57270 12.32850  16.70273 1.000 21.81657 ? 102 LEU A HD12 1 
ATOM   1229 H  HD13 . LEU A 1 79  ? -14.69093 11.11634  15.68283 1.000 21.81657 ? 102 LEU A HD13 1 
ATOM   1230 H  HD21 . LEU A 1 79  ? -15.62567 9.21238   17.78363 1.000 20.21747 ? 102 LEU A HD21 1 
ATOM   1231 H  HD22 . LEU A 1 79  ? -14.54937 8.72247   16.72294 1.000 20.21747 ? 102 LEU A HD22 1 
ATOM   1232 H  HD23 . LEU A 1 79  ? -14.23412 8.62606   18.27691 1.000 20.21747 ? 102 LEU A HD23 1 
ATOM   1233 N  N    . VAL A 1 80  ? -9.98266  8.58775   16.81943 1.000 14.71858 ? 103 VAL A N    1 
ATOM   1234 C  CA   . VAL A 1 80  ? -8.70284  8.45179   16.14347 1.000 15.83054 ? 103 VAL A CA   1 
ATOM   1235 C  C    . VAL A 1 80  ? -8.98762  8.20502   14.66034 1.000 17.58582 ? 103 VAL A C    1 
ATOM   1236 O  O    . VAL A 1 80  ? -9.83524  8.88681   14.06302 1.000 19.30702 ? 103 VAL A O    1 
ATOM   1237 C  CB   . VAL A 1 80  ? -7.81206  7.41098   16.84627 1.000 16.16790 ? 103 VAL A CB   1 
ATOM   1238 C  CG1  . VAL A 1 80  ? -7.34729  7.96436   18.21615 1.000 16.07488 ? 103 VAL A CG1  1 
ATOM   1239 C  CG2  . VAL A 1 80  ? -8.51128  6.09569   17.00312 1.000 16.05705 ? 103 VAL A CG2  1 
ATOM   1240 H  H    . VAL A 1 80  ? -10.50096 7.90834   16.72267 1.000 17.66230 ? 103 VAL A H    1 
ATOM   1241 H  HA   . VAL A 1 80  ? -8.18141  9.26897   16.17847 1.000 18.99665 ? 103 VAL A HA   1 
ATOM   1242 H  HB   . VAL A 1 80  ? -7.03172  7.24459   16.29465 1.000 19.40148 ? 103 VAL A HB   1 
ATOM   1243 H  HG11 . VAL A 1 80  ? -6.79603  7.29796   18.65537 1.000 19.28986 ? 103 VAL A HG11 1 
ATOM   1244 H  HG12 . VAL A 1 80  ? -6.83441  8.77492   18.07175 1.000 19.28986 ? 103 VAL A HG12 1 
ATOM   1245 H  HG13 . VAL A 1 80  ? -8.12713  8.15871   18.75927 1.000 19.28986 ? 103 VAL A HG13 1 
ATOM   1246 H  HG21 . VAL A 1 80  ? -7.94846  5.49855   17.52037 1.000 19.26846 ? 103 VAL A HG21 1 
ATOM   1247 H  HG22 . VAL A 1 80  ? -9.35303  6.23845   17.46352 1.000 19.26846 ? 103 VAL A HG22 1 
ATOM   1248 H  HG23 . VAL A 1 80  ? -8.67461  5.71813   16.12467 1.000 19.26846 ? 103 VAL A HG23 1 
ATOM   1249 N  N    . ASN A 1 81  ? -8.28347  7.27013   14.03816 1.000 17.48696 ? 104 ASN A N    1 
ATOM   1250 C  CA   . ASN A 1 81  ? -8.31311  7.11234   12.59574 1.000 18.08663 ? 104 ASN A CA   1 
ATOM   1251 C  C    . ASN A 1 81  ? -9.25172  6.02382   12.10275 1.000 18.69219 ? 104 ASN A C    1 
ATOM   1252 O  O    . ASN A 1 81  ? -9.39241  5.85203   10.88952 1.000 20.76919 ? 104 ASN A O    1 
ATOM   1253 C  CB   . ASN A 1 81  ? -6.90436  6.80089   12.09394 1.000 19.35087 ? 104 ASN A CB   1 
ATOM   1254 C  CG   . ASN A 1 81  ? -6.37269  5.48917   12.65605 1.000 20.02254 ? 104 ASN A CG   1 
ATOM   1255 O  OD1  . ASN A 1 81  ? -6.71960  5.09741   13.77920 1.000 17.99545 ? 104 ASN A OD1  1 
ATOM   1256 N  ND2  . ASN A 1 81  ? -5.52166  4.81954   11.89440 1.000 22.30991 ? 104 ASN A ND2  1 
ATOM   1257 H  H    . ASN A 1 81  ? -7.77251  6.70611   14.43866 1.000 20.98436 ? 104 ASN A H    1 
ATOM   1258 H  HA   . ASN A 1 81  ? -8.62058  7.94956   12.21440 1.000 21.70395 ? 104 ASN A HA   1 
ATOM   1259 H  HB2  . ASN A 1 81  ? -6.91876  6.73190   11.12651 1.000 23.22104 ? 104 ASN A HB2  1 
ATOM   1260 H  HB3  . ASN A 1 81  ? -6.30435  7.51249   12.36691 1.000 23.22104 ? 104 ASN A HB3  1 
ATOM   1261 H  HD21 . ASN A 1 81  ? -5.19419  4.07324   12.16900 1.000 26.77189 ? 104 ASN A HD21 1 
ATOM   1262 H  HD22 . ASN A 1 81  ? -5.29633  5.13085   11.12504 1.000 26.77189 ? 104 ASN A HD22 1 
ATOM   1263 N  N    . TYR A 1 82  ? -9.87187  5.26316   12.99531 1.000 16.27840 ? 105 TYR A N    1 
ATOM   1264 C  CA   . TYR A 1 82  ? -10.72736 4.14827   12.58476 1.000 14.87644 ? 105 TYR A CA   1 
ATOM   1265 C  C    . TYR A 1 82  ? -11.70351 3.88917   13.73657 1.000 14.08582 ? 105 TYR A C    1 
ATOM   1266 O  O    . TYR A 1 82  ? -11.37201 3.17570   14.69064 1.000 14.81951 ? 105 TYR A O    1 
ATOM   1267 C  CB   . TYR A 1 82  ? -9.91187  2.91167   12.23899 1.000 15.75407 ? 105 TYR A CB   1 
ATOM   1268 C  CG   . TYR A 1 82  ? -10.76950 1.87419   11.58329 1.000 15.91428 ? 105 TYR A CG   1 
ATOM   1269 C  CD1  . TYR A 1 82  ? -11.22034 2.04109   10.28078 1.000 21.03323 ? 105 TYR A CD1  1 
ATOM   1270 C  CD2  . TYR A 1 82  ? -11.19193 0.74492   12.27926 1.000 15.16501 ? 105 TYR A CD2  1 
ATOM   1271 C  CE1  . TYR A 1 82  ? -12.02464 1.12176   9.69416  1.000 23.38479 ? 105 TYR A CE1  1 
ATOM   1272 C  CE2  . TYR A 1 82  ? -12.01970 -0.18343  11.68428 1.000 17.94586 ? 105 TYR A CE2  1 
ATOM   1273 C  CZ   . TYR A 1 82  ? -12.42768 0.00791   10.39369 1.000 23.15287 ? 105 TYR A CZ   1 
ATOM   1274 O  OH   . TYR A 1 82  ? -13.24424 -0.90550  9.76446  1.000 27.64556 ? 105 TYR A OH   1 
ATOM   1275 H  H    . TYR A 1 82  ? -9.81621  5.36863   13.84700 1.000 19.53408 ? 105 TYR A H    1 
ATOM   1276 H  HA   . TYR A 1 82  ? -11.23276 4.39885   11.79566 1.000 17.85172 ? 105 TYR A HA   1 
ATOM   1277 H  HB2  . TYR A 1 82  ? -9.19984  3.15500   11.62686 1.000 18.90488 ? 105 TYR A HB2  1 
ATOM   1278 H  HB3  . TYR A 1 82  ? -9.53738  2.53437   13.05034 1.000 18.90488 ? 105 TYR A HB3  1 
ATOM   1279 H  HD1  . TYR A 1 82  ? -10.96589 2.79704   9.80256  1.000 25.23987 ? 105 TYR A HD1  1 
ATOM   1280 H  HD2  . TYR A 1 82  ? -10.91224 0.61506   13.15665 1.000 18.19801 ? 105 TYR A HD2  1 
ATOM   1281 H  HE1  . TYR A 1 82  ? -12.30503 1.24418   8.81592  1.000 28.06175 ? 105 TYR A HE1  1 
ATOM   1282 H  HE2  . TYR A 1 82  ? -12.29836 -0.93406  12.15737 1.000 21.53503 ? 105 TYR A HE2  1 
ATOM   1283 H  HH   . TYR A 1 82  ? -13.74978 -1.27327  10.32550 1.000 33.17467 ? 105 TYR A HH   1 
ATOM   1284 N  N    . ASN A 1 83  ? -12.89950 4.47083   13.61471 1.000 14.27971 ? 106 ASN A N    1 
ATOM   1285 C  CA   . ASN A 1 83  ? -13.84220 4.59615   14.72835 1.000 15.45231 ? 106 ASN A CA   1 
ATOM   1286 C  C    . ASN A 1 83  ? -15.24819 4.17244   14.30594 1.000 14.49730 ? 106 ASN A C    1 
ATOM   1287 O  O    . ASN A 1 83  ? -16.22225 4.87004   14.57852 1.000 14.63422 ? 106 ASN A O    1 
ATOM   1288 C  CB   . ASN A 1 83  ? -13.89195 6.04117   15.23902 1.000 17.73012 ? 106 ASN A CB   1 
ATOM   1289 C  CG   . ASN A 1 83  ? -12.57850 6.76412   15.11249 1.000 17.72335 ? 106 ASN A CG   1 
ATOM   1290 O  OD1  . ASN A 1 83  ? -11.57830 6.36596   15.70160 1.000 17.53512 ? 106 ASN A OD1  1 
ATOM   1291 N  ND2  . ASN A 1 83  ? -12.57494 7.85416   14.35022 1.000 18.40142 ? 106 ASN A ND2  1 
ATOM   1292 H  H    . ASN A 1 83  ? -13.19400 4.80802   12.88042 1.000 17.13565 ? 106 ASN A H    1 
ATOM   1293 H  HA   . ASN A 1 83  ? -13.53564 4.01372   15.44087 1.000 18.54278 ? 106 ASN A HA   1 
ATOM   1294 H  HB2  . ASN A 1 83  ? -14.55253 6.53264   14.72620 1.000 21.27615 ? 106 ASN A HB2  1 
ATOM   1295 H  HB3  . ASN A 1 83  ? -14.13835 6.03412   16.17718 1.000 21.27615 ? 106 ASN A HB3  1 
ATOM   1296 H  HD21 . ASN A 1 83  ? -11.84906 8.30332   14.24556 1.000 22.08170 ? 106 ASN A HD21 1 
ATOM   1297 H  HD22 . ASN A 1 83  ? -13.29853 8.10978   13.96205 1.000 22.08170 ? 106 ASN A HD22 1 
ATOM   1298 N  N    . PRO A 1 84  ? -15.38999 3.03541   13.61663 1.000 13.89125 ? 107 PRO A N    1 
ATOM   1299 C  CA   . PRO A 1 84  ? -16.70094 2.69675   13.03220 1.000 15.80878 ? 107 PRO A CA   1 
ATOM   1300 C  C    . PRO A 1 84  ? -17.83967 2.62991   14.03420 1.000 15.25127 ? 107 PRO A C    1 
ATOM   1301 O  O    . PRO A 1 84  ? -18.97528 2.98524   13.69229 1.000 17.70929 ? 107 PRO A O    1 
ATOM   1302 C  CB   . PRO A 1 84  ? -16.43249 1.33141   12.37969 1.000 17.26858 ? 107 PRO A CB   1 
ATOM   1303 C  CG   . PRO A 1 84  ? -15.26472 0.78108   13.13744 1.000 16.62328 ? 107 PRO A CG   1 
ATOM   1304 C  CD   . PRO A 1 84  ? -14.39005 1.98285   13.37316 1.000 14.86239 ? 107 PRO A CD   1 
ATOM   1305 H  HA   . PRO A 1 84  ? -16.92866 3.35273   12.35490 1.000 18.97054 ? 107 PRO A HA   1 
ATOM   1306 H  HB2  . PRO A 1 84  ? -17.21038 0.75945   12.47272 1.000 20.72229 ? 107 PRO A HB2  1 
ATOM   1307 H  HB3  . PRO A 1 84  ? -16.21663 1.44781   11.44120 1.000 20.72229 ? 107 PRO A HB3  1 
ATOM   1308 H  HG2  . PRO A 1 84  ? -15.56150 0.39326   13.97555 1.000 19.94793 ? 107 PRO A HG2  1 
ATOM   1309 H  HG3  . PRO A 1 84  ? -14.80567 0.11172   12.60629 1.000 19.94793 ? 107 PRO A HG3  1 
ATOM   1310 H  HD2  . PRO A 1 84  ? -13.81862 1.85533   14.14653 1.000 17.83487 ? 107 PRO A HD2  1 
ATOM   1311 H  HD3  . PRO A 1 84  ? -13.85121 2.18394   12.59206 1.000 17.83487 ? 107 PRO A HD3  1 
ATOM   1312 N  N    . ILE A 1 85  ? -17.58318 2.13940   15.24172 1.000 14.62597 ? 108 ILE A N    1 
ATOM   1313 C  CA   . ILE A 1 85  ? -18.61198 2.05680   16.27140 1.000 15.12874 ? 108 ILE A CA   1 
ATOM   1314 C  C    . ILE A 1 85  ? -18.58467 3.28505   17.16115 1.000 14.37959 ? 108 ILE A C    1 
ATOM   1315 O  O    . ILE A 1 85  ? -19.61340 3.91039   17.41948 1.000 15.55075 ? 108 ILE A O    1 
ATOM   1316 C  CB   . ILE A 1 85  ? -18.44295 0.76907   17.10424 1.000 15.55074 ? 108 ILE A CB   1 
ATOM   1317 C  CG1  . ILE A 1 85  ? -18.47156 -0.45532  16.19322 1.000 16.55202 ? 108 ILE A CG1  1 
ATOM   1318 C  CG2  . ILE A 1 85  ? -19.52744 0.67987   18.17835 1.000 16.62297 ? 108 ILE A CG2  1 
ATOM   1319 C  CD1  . ILE A 1 85  ? -19.68895 -0.56018  15.31377 1.000 18.46757 ? 108 ILE A CD1  1 
ATOM   1320 H  H    . ILE A 1 85  ? -16.81468 1.84533   15.49178 1.000 17.55117 ? 108 ILE A H    1 
ATOM   1321 H  HA   . ILE A 1 85  ? -19.47594 2.01240   15.83266 1.000 18.15449 ? 108 ILE A HA   1 
ATOM   1322 H  HB   . ILE A 1 85  ? -17.58111 0.79781   17.54842 1.000 18.66088 ? 108 ILE A HB   1 
ATOM   1323 H  HG12 . ILE A 1 85  ? -17.69461 -0.42563  15.61324 1.000 19.86242 ? 108 ILE A HG12 1 
ATOM   1324 H  HG13 . ILE A 1 85  ? -18.44223 -1.25145  16.74660 1.000 19.86242 ? 108 ILE A HG13 1 
ATOM   1325 H  HG21 . ILE A 1 85  ? -19.49722 -0.20011  18.58532 1.000 19.94756 ? 108 ILE A HG21 1 
ATOM   1326 H  HG22 . ILE A 1 85  ? -19.36374 1.36059   18.84971 1.000 19.94756 ? 108 ILE A HG22 1 
ATOM   1327 H  HG23 . ILE A 1 85  ? -20.39335 0.82385   17.76558 1.000 19.94756 ? 108 ILE A HG23 1 
ATOM   1328 H  HD11 . ILE A 1 85  ? -19.67526 -1.41535  14.85616 1.000 22.16108 ? 108 ILE A HD11 1 
ATOM   1329 H  HD12 . ILE A 1 85  ? -20.48389 -0.49298  15.86555 1.000 22.16108 ? 108 ILE A HD12 1 
ATOM   1330 H  HD13 . ILE A 1 85  ? -19.67383 0.16180   14.66614 1.000 22.16108 ? 108 ILE A HD13 1 
ATOM   1331 N  N    . ALA A 1 86  ? -17.40206 3.64459   17.64974 1.000 14.04878 ? 109 ALA A N    1 
ATOM   1332 C  CA   . ALA A 1 86  ? -17.31037 4.73351   18.61031 1.000 14.90306 ? 109 ALA A CA   1 
ATOM   1333 C  C    . ALA A 1 86  ? -17.85449 6.04589   18.05899 1.000 15.67267 ? 109 ALA A C    1 
ATOM   1334 O  O    . ALA A 1 86  ? -18.43740 6.83713   18.80427 1.000 16.27483 ? 109 ALA A O    1 
ATOM   1335 C  CB   . ALA A 1 86  ? -15.86270 4.90453   19.06155 1.000 15.07701 ? 109 ALA A CB   1 
ATOM   1336 H  H    . ALA A 1 86  ? -16.65075 3.27993   17.44440 1.000 16.85853 ? 109 ALA A H    1 
ATOM   1337 H  HA   . ALA A 1 86  ? -17.85222 4.50080   19.38047 1.000 17.88367 ? 109 ALA A HA   1 
ATOM   1338 H  HB1  . ALA A 1 86  ? -15.80797 5.65988   19.66764 1.000 18.09241 ? 109 ALA A HB1  1 
ATOM   1339 H  HB2  . ALA A 1 86  ? -15.57529 4.09600   19.51385 1.000 18.09241 ? 109 ALA A HB2  1 
ATOM   1340 H  HB3  . ALA A 1 86  ? -15.30606 5.06388   18.28331 1.000 18.09241 ? 109 ALA A HB3  1 
ATOM   1341 N  N    . GLU A 1 87  ? -17.66605 6.30956   16.76340 1.000 16.35668 ? 110 GLU A N    1 
ATOM   1342 C  CA   . GLU A 1 87  ? -18.15197 7.57462   16.21474 1.000 19.50755 ? 110 GLU A CA   1 
ATOM   1343 C  C    . GLU A 1 87  ? -19.65839 7.70308   16.37306 1.000 20.85345 ? 110 GLU A C    1 
ATOM   1344 O  O    . GLU A 1 87  ? -20.17668 8.82241   16.49742 1.000 21.85996 ? 110 GLU A O    1 
ATOM   1345 C  CB   . GLU A 1 87  ? -17.73177 7.74189   14.75257 1.000 22.46127 ? 110 GLU A CB   1 
ATOM   1346 C  CG   . GLU A 1 87  ? -18.39277 6.78925   13.77735 1.000 26.95708 ? 110 GLU A CG   1 
ATOM   1347 C  CD   . GLU A 1 87  ? -17.71863 6.76882   12.41665 1.000 31.27470 ? 110 GLU A CD   1 
ATOM   1348 O  OE1  . GLU A 1 87  ? -16.63818 7.37802   12.26638 1.000 32.77379 ? 110 GLU A OE1  1 
ATOM   1349 O  OE2  . GLU A 1 87  ? -18.26743 6.13271   11.49737 1.000 32.58065 ? 110 GLU A OE2  1 
ATOM   1350 H  H    . GLU A 1 87  ? -17.27360 5.79073   16.20091 1.000 19.62801 ? 110 GLU A H    1 
ATOM   1351 H  HA   . GLU A 1 87  ? -17.73685 8.30190   16.70427 1.000 23.40906 ? 110 GLU A HA   1 
ATOM   1352 H  HB2  . GLU A 1 87  ? -17.95298 8.64365   14.47184 1.000 26.95352 ? 110 GLU A HB2  1 
ATOM   1353 H  HB3  . GLU A 1 87  ? -16.77403 7.60091   14.69135 1.000 26.95352 ? 110 GLU A HB3  1 
ATOM   1354 H  HG2  . GLU A 1 87  ? -18.35757 5.89095   14.14165 1.000 32.34850 ? 110 GLU A HG2  1 
ATOM   1355 H  HG3  . GLU A 1 87  ? -19.31555 7.05948   13.64949 1.000 32.34850 ? 110 GLU A HG3  1 
ATOM   1356 N  N    . LYS A 1 88  ? -20.37637 6.57800   16.39198 1.000 20.08400 ? 111 LYS A N    1 
ATOM   1357 C  CA   . LYS A 1 88  ? -21.82439 6.62080   16.53698 1.000 20.47006 ? 111 LYS A CA   1 
ATOM   1358 C  C    . LYS A 1 88  ? -22.26303 6.86098   17.97568 1.000 19.89977 ? 111 LYS A C    1 
ATOM   1359 O  O    . LYS A 1 88  ? -23.45625 7.08626   18.21404 1.000 22.52519 ? 111 LYS A O    1 
ATOM   1360 C  CB   . LYS A 1 88  ? -22.45749 5.29978   16.08561 1.000 24.46483 ? 111 LYS A CB   1 
ATOM   1361 C  CG   . LYS A 1 88  ? -22.12741 4.83908   14.67887 1.000 30.07746 ? 111 LYS A CG   1 
ATOM   1362 C  CD   . LYS A 1 88  ? -22.76890 3.46344   14.43804 1.000 35.58390 ? 111 LYS A CD   1 
ATOM   1363 C  CE   . LYS A 1 88  ? -22.16648 2.73460   13.24640 1.000 40.52920 ? 111 LYS A CE   1 
ATOM   1364 N  NZ   . LYS A 1 88  ? -22.76776 1.37554   13.04554 1.000 43.22705 ? 111 LYS A NZ   1 
ATOM   1365 H  H    . LYS A 1 88  ? -20.04746 5.78639   16.32290 1.000 24.10080 ? 111 LYS A H    1 
ATOM   1366 H  HA   . LYS A 1 88  ? -22.15186 7.33611   15.96954 1.000 24.56407 ? 111 LYS A HA   1 
ATOM   1367 H  HB2  . LYS A 1 88  ? -22.16171 4.60161   16.69056 1.000 29.35780 ? 111 LYS A HB2  1 
ATOM   1368 H  HB3  . LYS A 1 88  ? -23.42152 5.39517   16.13508 1.000 29.35780 ? 111 LYS A HB3  1 
ATOM   1369 H  HG2  . LYS A 1 88  ? -22.48214 5.46962   14.03274 1.000 36.09295 ? 111 LYS A HG2  1 
ATOM   1370 H  HG3  . LYS A 1 88  ? -21.16630 4.76136   14.57343 1.000 36.09295 ? 111 LYS A HG3  1 
ATOM   1371 H  HD2  . LYS A 1 88  ? -22.63811 2.91103   15.22458 1.000 42.70068 ? 111 LYS A HD2  1 
ATOM   1372 H  HD3  . LYS A 1 88  ? -23.71682 3.58128   14.26929 1.000 42.70068 ? 111 LYS A HD3  1 
ATOM   1373 H  HE2  . LYS A 1 88  ? -22.32305 3.25521   12.44307 1.000 48.63504 ? 111 LYS A HE2  1 
ATOM   1374 H  HE3  . LYS A 1 88  ? -21.21349 2.62437   13.38983 1.000 48.63504 ? 111 LYS A HE3  1 
ATOM   1375 H  HZ1  . LYS A 1 88  ? -22.21616 0.86626   12.56756 1.000 51.87246 ? 111 LYS A HZ1  1 
ATOM   1376 H  HZ2  . LYS A 1 88  ? -22.91058 0.98644   13.83313 1.000 51.87246 ? 111 LYS A HZ2  1 
ATOM   1377 H  HZ3  . LYS A 1 88  ? -23.54270 1.44635   12.61360 1.000 51.87246 ? 111 LYS A HZ3  1 
ATOM   1378 N  N    . HIS A 1 89  ? -21.33893 6.79540   18.93647 1.000 18.11074 ? 112 HIS A N    1 
ATOM   1379 C  CA   . HIS A 1 89  ? -21.66450 6.91691   20.35095 1.000 17.88965 ? 112 HIS A CA   1 
ATOM   1380 C  C    . HIS A 1 89  ? -21.02078 8.13564   20.98518 1.000 16.77862 ? 112 HIS A C    1 
ATOM   1381 O  O    . HIS A 1 89  ? -21.02864 8.25994   22.21373 1.000 17.03011 ? 112 HIS A O    1 
ATOM   1382 C  CB   . HIS A 1 89  ? -21.26855 5.63567   21.09461 1.000 18.35339 ? 112 HIS A CB   1 
ATOM   1383 C  CG   . HIS A 1 89  ? -22.06350 4.44428   20.66839 1.000 19.45367 ? 112 HIS A CG   1 
ATOM   1384 N  ND1  . HIS A 1 89  ? -23.21974 4.04950   21.30732 1.000 20.42465 ? 112 HIS A ND1  1 
ATOM   1385 C  CD2  . HIS A 1 89  ? -21.88938 3.58465   19.63636 1.000 19.94856 ? 112 HIS A CD2  1 
ATOM   1386 C  CE1  . HIS A 1 89  ? -23.71485 2.98640   20.69456 1.000 19.91897 ? 112 HIS A CE1  1 
ATOM   1387 N  NE2  . HIS A 1 89  ? -22.93436 2.69413   19.67103 1.000 20.32090 ? 112 HIS A NE2  1 
ATOM   1388 H  H    . HIS A 1 89  ? -20.50013 6.67853   18.78694 1.000 21.73289 ? 112 HIS A H    1 
ATOM   1389 H  HA   . HIS A 1 89  ? -22.62398 7.01994   20.44941 1.000 21.46758 ? 112 HIS A HA   1 
ATOM   1390 H  HB2  . HIS A 1 89  ? -20.33255 5.44816   20.92246 1.000 22.02407 ? 112 HIS A HB2  1 
ATOM   1391 H  HB3  . HIS A 1 89  ? -21.41136 5.76637   22.04510 1.000 22.02407 ? 112 HIS A HB3  1 
ATOM   1392 H  HD2  . HIS A 1 89  ? -21.19302 3.59538   19.02002 1.000 23.93827 ? 112 HIS A HD2  1 
ATOM   1393 H  HE1  . HIS A 1 89  ? -24.48241 2.52371   20.94288 1.000 23.90276 ? 112 HIS A HE1  1 
ATOM   1394 H  HE2  . HIS A 1 89  ? -23.05995 2.04987   19.11538 1.000 24.38508 ? 112 HIS A HE2  1 
ATOM   1395 N  N    . VAL A 1 90  ? -20.47330 9.04288   20.17818 1.000 18.00681 ? 113 VAL A N    1 
ATOM   1396 C  CA   . VAL A 1 90  ? -19.87960 10.25398  20.72076 1.000 18.06378 ? 113 VAL A CA   1 
ATOM   1397 C  C    . VAL A 1 90  ? -20.92363 10.99689  21.53689 1.000 17.91086 ? 113 VAL A C    1 
ATOM   1398 O  O    . VAL A 1 90  ? -22.09490 11.11032  21.14113 1.000 19.67452 ? 113 VAL A O    1 
ATOM   1399 C  CB   . VAL A 1 90  ? -19.30749 11.12482  19.58850 1.000 19.54852 ? 113 VAL A CB   1 
ATOM   1400 C  CG1  . VAL A 1 90  ? -18.93077 12.51274  20.11011 1.000 20.49130 ? 113 VAL A CG1  1 
ATOM   1401 C  CG2  . VAL A 1 90  ? -18.10383 10.44578  18.95860 1.000 21.35741 ? 113 VAL A CG2  1 
ATOM   1402 H  H    . VAL A 1 90  ? -20.43450 8.97900   19.32144 1.000 21.60817 ? 113 VAL A H    1 
ATOM   1403 H  HA   . VAL A 1 90  ? -19.14377 10.02097  21.30826 1.000 21.67654 ? 113 VAL A HA   1 
ATOM   1404 H  HB   . VAL A 1 90  ? -19.98741 11.23704  18.90586 1.000 23.45823 ? 113 VAL A HB   1 
ATOM   1405 H  HG11 . VAL A 1 90  ? -18.50960 13.01518  19.39522 1.000 24.58956 ? 113 VAL A HG11 1 
ATOM   1406 H  HG12 . VAL A 1 90  ? -19.73476 12.96811  20.40530 1.000 24.58956 ? 113 VAL A HG12 1 
ATOM   1407 H  HG13 . VAL A 1 90  ? -18.31466 12.41447  20.85284 1.000 24.58956 ? 113 VAL A HG13 1 
ATOM   1408 H  HG21 . VAL A 1 90  ? -17.77513 10.99688  18.23117 1.000 25.62889 ? 113 VAL A HG21 1 
ATOM   1409 H  HG22 . VAL A 1 90  ? -17.41316 10.33964  19.63135 1.000 25.62889 ? 113 VAL A HG22 1 
ATOM   1410 H  HG23 . VAL A 1 90  ? -18.37237 9.57724   18.62033 1.000 25.62889 ? 113 VAL A HG23 1 
ATOM   1411 N  N    . ASN A 1 91  ? -20.49160 11.50844  22.68827 1.000 17.24115 ? 114 ASN A N    1 
ATOM   1412 C  CA   . ASN A 1 91  ? -21.27457 12.24359  23.66867 1.000 17.77575 ? 114 ASN A CA   1 
ATOM   1413 C  C    . ASN A 1 91  ? -22.14726 11.32476  24.50617 1.000 17.91774 ? 114 ASN A C    1 
ATOM   1414 O  O    . ASN A 1 91  ? -22.91662 11.81959  25.33137 1.000 19.74218 ? 114 ASN A O    1 
ATOM   1415 C  CB   . ASN A 1 91  ? -22.07414 13.39421  23.04739 1.000 20.39051 ? 114 ASN A CB   1 
ATOM   1416 C  CG   . ASN A 1 91  ? -21.16625 14.44522  22.49110 1.000 24.18067 ? 114 ASN A CG   1 
ATOM   1417 O  OD1  . ASN A 1 91  ? -20.13706 14.74935  23.09882 1.000 24.40481 ? 114 ASN A OD1  1 
ATOM   1418 N  ND2  . ASN A 1 91  ? -21.49404 14.97450  21.31953 1.000 27.32863 ? 114 ASN A ND2  1 
ATOM   1419 H  H    . ASN A 1 91  ? -19.67268 11.43132  22.93930 1.000 20.68939 ? 114 ASN A H    1 
ATOM   1420 H  HA   . ASN A 1 91  ? -20.67686 12.66594  24.30527 1.000 21.33090 ? 114 ASN A HA   1 
ATOM   1421 H  HB2  . ASN A 1 91  ? -22.62440 13.05131  22.32590 1.000 24.46862 ? 114 ASN A HB2  1 
ATOM   1422 H  HB3  . ASN A 1 91  ? -22.63399 13.80117  23.72698 1.000 24.46862 ? 114 ASN A HB3  1 
ATOM   1423 H  HD21 . ASN A 1 91  ? -20.99669 15.58147  20.96765 1.000 32.79436 ? 114 ASN A HD21 1 
ATOM   1424 H  HD22 . ASN A 1 91  ? -22.20388 14.71062  20.91198 1.000 32.79436 ? 114 ASN A HD22 1 
ATOM   1425 N  N    . GLY A 1 92  ? -22.05255 10.01633  24.32770 1.000 16.23545 ? 115 GLY A N    1 
ATOM   1426 C  CA   . GLY A 1 92  ? -22.68013 9.06777   25.21411 1.000 16.15696 ? 115 GLY A CA   1 
ATOM   1427 C  C    . GLY A 1 92  ? -21.62554 8.17951   25.83212 1.000 14.78137 ? 115 GLY A C    1 
ATOM   1428 O  O    . GLY A 1 92  ? -20.44161 8.52339   25.82939 1.000 16.24043 ? 115 GLY A O    1 
ATOM   1429 H  H    . GLY A 1 92  ? -21.61834 9.64850   23.68289 1.000 19.48254 ? 115 GLY A H    1 
ATOM   1430 H  HA2  . GLY A 1 92  ? -23.15454 9.53577   25.91896 1.000 19.38835 ? 115 GLY A HA2  1 
ATOM   1431 H  HA3  . GLY A 1 92  ? -23.30926 8.51846   24.72080 1.000 19.38835 ? 115 GLY A HA3  1 
ATOM   1432 N  N    . THR A 1 93  ? -22.04361 7.04379   26.36839 1.000 14.50781 ? 116 THR A N    1 
ATOM   1433 C  CA   . THR A 1 93  ? -21.14213 6.07182   26.96072 1.000 13.71439 ? 116 THR A CA   1 
ATOM   1434 C  C    . THR A 1 93  ? -21.32107 4.73100   26.26202 1.000 13.71883 ? 116 THR A C    1 
ATOM   1435 O  O    . THR A 1 93  ? -22.35774 4.44792   25.64100 1.000 14.93770 ? 116 THR A O    1 
ATOM   1436 C  CB   . THR A 1 93  ? -21.36052 5.89643   28.47521 1.000 14.38444 ? 116 THR A CB   1 
ATOM   1437 O  OG1  . THR A 1 93  ? -22.65943 5.33933   28.69936 1.000 13.46629 ? 116 THR A OG1  1 
ATOM   1438 C  CG2  . THR A 1 93  ? -21.20539 7.21161   29.22875 1.000 15.88725 ? 116 THR A CG2  1 
ATOM   1439 H  H    . THR A 1 93  ? -22.86984 6.80748   26.40166 1.000 17.40938 ? 116 THR A H    1 
ATOM   1440 H  HA   . THR A 1 93  ? -20.23102 6.38152   26.83881 1.000 16.45727 ? 116 THR A HA   1 
ATOM   1441 H  HB   . THR A 1 93  ? -20.68541 5.29664   28.82929 1.000 17.26132 ? 116 THR A HB   1 
ATOM   1442 H  HG1  . THR A 1 93  ? -23.24604 5.93433   28.61297 1.000 16.15954 ? 116 THR A HG1  1 
ATOM   1443 H  HG21 . THR A 1 93  ? -21.41063 7.08208   30.16790 1.000 19.06470 ? 116 THR A HG21 1 
ATOM   1444 H  HG22 . THR A 1 93  ? -20.29460 7.53521   29.14729 1.000 19.06470 ? 116 THR A HG22 1 
ATOM   1445 H  HG23 . THR A 1 93  ? -21.80962 7.87663   28.86329 1.000 19.06470 ? 116 THR A HG23 1 
ATOM   1446 N  N    . MET A 1 94  ? -20.29114 3.91195   26.36710 1.000 14.19286 ? 117 MET A N    1 
ATOM   1447 C  CA   . MET A 1 94  ? -20.33713 2.50896   25.99032 1.000 13.42517 ? 117 MET A CA   1 
ATOM   1448 C  C    . MET A 1 94  ? -19.85171 1.70756   27.18683 1.000 13.69699 ? 117 MET A C    1 
ATOM   1449 O  O    . MET A 1 94  ? -18.94638 2.15020   27.90340 1.000 14.05414 ? 117 MET A O    1 
ATOM   1450 C  CB   . MET A 1 94  ? -19.43285 2.22918   24.79774 1.000 13.52210 ? 117 MET A CB   1 
ATOM   1451 C  CG   . MET A 1 94  ? -19.89448 2.90988   23.51107 1.000 14.69247 ? 117 MET A CG   1 
ATOM   1452 S  SD   . MET A 1 94  ? -18.72181 2.74734   22.14822 1.000 14.66910 ? 117 MET A SD   1 
ATOM   1453 C  CE   . MET A 1 94  ? -18.74068 0.99169   21.85233 1.000 14.96552 ? 117 MET A CE   1 
ATOM   1454 H  H    . MET A 1 94  ? -19.52195 4.15378   26.66619 1.000 17.03144 ? 117 MET A H    1 
ATOM   1455 H  HA   . MET A 1 94  ? -21.23901 2.25106   25.74335 1.000 16.11020 ? 117 MET A HA   1 
ATOM   1456 H  HB2  . MET A 1 94  ? -18.54007 2.55000   25.00001 1.000 16.22652 ? 117 MET A HB2  1 
ATOM   1457 H  HB3  . MET A 1 94  ? -19.41330 1.27270   24.63755 1.000 16.22652 ? 117 MET A HB3  1 
ATOM   1458 H  HG2  . MET A 1 94  ? -20.73310 2.51174   23.22982 1.000 17.63096 ? 117 MET A HG2  1 
ATOM   1459 H  HG3  . MET A 1 94  ? -20.01821 3.85618   23.68460 1.000 17.63096 ? 117 MET A HG3  1 
ATOM   1460 H  HE1  . MET A 1 94  ? -18.25016 0.80358   21.03691 1.000 17.95862 ? 117 MET A HE1  1 
ATOM   1461 H  HE2  . MET A 1 94  ? -18.32173 0.54059   22.60191 1.000 17.95862 ? 117 MET A HE2  1 
ATOM   1462 H  HE3  . MET A 1 94  ? -19.66020 0.69675   21.76071 1.000 17.95862 ? 117 MET A HE3  1 
ATOM   1463 N  N    . SER A 1 95  ? -20.45073 0.54114   27.40750 1.000 13.35437 ? 118 SER A N    1 
ATOM   1464 C  CA   . SER A 1 95  ? -19.96112 -0.33047  28.46431 1.000 13.29814 ? 118 SER A CA   1 
ATOM   1465 C  C    . SER A 1 95  ? -18.66356 -0.99782  28.01275 1.000 12.31664 ? 118 SER A C    1 
ATOM   1466 O  O    . SER A 1 95  ? -18.33802 -1.05742  26.81623 1.000 12.26948 ? 118 SER A O    1 
ATOM   1467 C  CB   . SER A 1 95  ? -20.97841 -1.41441  28.78339 1.000 13.65327 ? 118 SER A CB   1 
ATOM   1468 O  OG   . SER A 1 95  ? -21.11262 -2.27015  27.65523 1.000 14.72724 ? 118 SER A OG   1 
ATOM   1469 H  H    . SER A 1 95  ? -21.12631 0.24003   26.96873 1.000 16.02525 ? 118 SER A H    1 
ATOM   1470 H  HA   . SER A 1 95  ? -19.80452 0.19112   29.26700 1.000 15.95777 ? 118 SER A HA   1 
ATOM   1471 H  HB2  . SER A 1 95  ? -20.67242 -1.93036  29.54568 1.000 16.38392 ? 118 SER A HB2  1 
ATOM   1472 H  HB3  . SER A 1 95  ? -21.83506 -1.00509  28.98215 1.000 16.38392 ? 118 SER A HB3  1 
ATOM   1473 H  HG   . SER A 1 95  ? -21.75007 -2.80417  27.77391 1.000 17.67269 ? 118 SER A HG   1 
ATOM   1474 N  N    . LEU A 1 96  ? -17.91316 -1.51110  28.99243 1.000 13.20096 ? 119 LEU A N    1 
ATOM   1475 C  CA   . LEU A 1 96  ? -16.70435 -2.24859  28.65395 1.000 12.84676 ? 119 LEU A CA   1 
ATOM   1476 C  C    . LEU A 1 96  ? -17.02581 -3.48371  27.82607 1.000 11.97679 ? 119 LEU A C    1 
ATOM   1477 O  O    . LEU A 1 96  ? -16.23021 -3.86296  26.96541 1.000 11.92752 ? 119 LEU A O    1 
ATOM   1478 C  CB   . LEU A 1 96  ? -15.89194 -2.56435  29.91212 1.000 13.40572 ? 119 LEU A CB   1 
ATOM   1479 C  CG   . LEU A 1 96  ? -15.05937 -1.39534  30.45445 1.000 15.11100 ? 119 LEU A CG   1 
ATOM   1480 C  CD1  . LEU A 1 96  ? -14.49903 -1.73936  31.82956 1.000 16.36770 ? 119 LEU A CD1  1 
ATOM   1481 C  CD2  . LEU A 1 96  ? -13.94451 -1.01990  29.49147 1.000 16.03824 ? 119 LEU A CD2  1 
ATOM   1482 H  H    . LEU A 1 96  ? -18.08014 -1.44625  29.83357 1.000 15.84116 ? 119 LEU A H    1 
ATOM   1483 H  HA   . LEU A 1 96  ? -16.12678 -1.69297  28.10750 1.000 15.41611 ? 119 LEU A HA   1 
ATOM   1484 H  HB2  . LEU A 1 96  ? -16.50518 -2.83573  30.61298 1.000 16.08687 ? 119 LEU A HB2  1 
ATOM   1485 H  HB3  . LEU A 1 96  ? -15.27983 -3.28864  29.70810 1.000 16.08687 ? 119 LEU A HB3  1 
ATOM   1486 H  HG   . LEU A 1 96  ? -15.63305 -0.61857  30.54614 1.000 18.13319 ? 119 LEU A HG   1 
ATOM   1487 H  HD11 . LEU A 1 96  ? -13.97111 -0.99197  32.15146 1.000 19.64124 ? 119 LEU A HD11 1 
ATOM   1488 H  HD12 . LEU A 1 96  ? -15.23569 -1.90998  32.43710 1.000 19.64124 ? 119 LEU A HD12 1 
ATOM   1489 H  HD13 . LEU A 1 96  ? -13.94199 -2.52994  31.75483 1.000 19.64124 ? 119 LEU A HD13 1 
ATOM   1490 H  HD21 . LEU A 1 96  ? -13.37160 -0.36053  29.91325 1.000 19.24589 ? 119 LEU A HD21 1 
ATOM   1491 H  HD22 . LEU A 1 96  ? -13.43167 -1.81475  29.27675 1.000 19.24589 ? 119 LEU A HD22 1 
ATOM   1492 H  HD23 . LEU A 1 96  ? -14.33551 -0.65045  28.68430 1.000 19.24589 ? 119 LEU A HD23 1 
ATOM   1493 N  N    . ALA A 1 97  ? -18.19477 -4.10665  28.02698 1.000 12.39038 ? 120 ALA A N    1 
ATOM   1494 C  CA   . ALA A 1 97  ? -18.58930 -5.20065  27.14344 1.000 13.59818 ? 120 ALA A CA   1 
ATOM   1495 C  C    . ALA A 1 97  ? -18.76652 -4.71338  25.70298 1.000 11.82991 ? 120 ALA A C    1 
ATOM   1496 O  O    . ALA A 1 97  ? -18.31795 -5.36222  24.74897 1.000 12.30526 ? 120 ALA A O    1 
ATOM   1497 C  CB   . ALA A 1 97  ? -19.88192 -5.84990  27.64459 1.000 15.38818 ? 120 ALA A CB   1 
ATOM   1498 H  H    . ALA A 1 97  ? -18.75752 -3.91820  28.64940 1.000 14.86846 ? 120 ALA A H    1 
ATOM   1499 H  HA   . ALA A 1 97  ? -17.88806 -5.87072  27.15639 1.000 16.31781 ? 120 ALA A HA   1 
ATOM   1500 H  HB1  . ALA A 1 97  ? -20.13530 -6.56060  27.03499 1.000 18.46582 ? 120 ALA A HB1  1 
ATOM   1501 H  HB2  . ALA A 1 97  ? -19.72983 -6.21305  28.53109 1.000 18.46582 ? 120 ALA A HB2  1 
ATOM   1502 H  HB3  . ALA A 1 97  ? -20.58060 -5.17785  27.67782 1.000 18.46582 ? 120 ALA A HB3  1 
ATOM   1503 N  N    . GLU A 1 98  ? -19.45935 -3.58633  25.52239 1.000 12.03316 ? 121 GLU A N    1 
ATOM   1504 C  CA   . GLU A 1 98  ? -19.66349 -3.05333  24.18188 1.000 12.61216 ? 121 GLU A CA   1 
ATOM   1505 C  C    . GLU A 1 98  ? -18.34390 -2.67195  23.54079 1.000 11.41418 ? 121 GLU A C    1 
ATOM   1506 O  O    . GLU A 1 98  ? -18.15646 -2.85546  22.33315 1.000 11.99622 ? 121 GLU A O    1 
ATOM   1507 C  CB   . GLU A 1 98  ? -20.59328 -1.83803  24.25657 1.000 13.73909 ? 121 GLU A CB   1 
ATOM   1508 C  CG   . GLU A 1 98  ? -22.04130 -2.22873  24.52699 1.000 16.36455 ? 121 GLU A CG   1 
ATOM   1509 C  CD   . GLU A 1 98  ? -22.93628 -1.09923  24.98033 1.000 18.40775 ? 121 GLU A CD   1 
ATOM   1510 O  OE1  . GLU A 1 98  ? -22.45421 -0.02511  25.38798 1.000 17.85709 ? 121 GLU A OE1  1 
ATOM   1511 O  OE2  . GLU A 1 98  ? -24.16964 -1.29809  24.94886 1.000 21.13884 ? 121 GLU A OE2  1 
ATOM   1512 H  H    . GLU A 1 98  ? -19.81510 -3.12032  26.15158 1.000 14.43979 ? 121 GLU A H    1 
ATOM   1513 H  HA   . GLU A 1 98  ? -20.08190 -3.72963  23.62651 1.000 15.13460 ? 121 GLU A HA   1 
ATOM   1514 H  HB2  . GLU A 1 98  ? -20.29831 -1.25713  24.97521 1.000 16.48691 ? 121 GLU A HB2  1 
ATOM   1515 H  HB3  . GLU A 1 98  ? -20.56184 -1.36266  23.41162 1.000 16.48691 ? 121 GLU A HB3  1 
ATOM   1516 H  HG2  . GLU A 1 98  ? -22.41999 -2.58839  23.70959 1.000 19.63746 ? 121 GLU A HG2  1 
ATOM   1517 H  HG3  . GLU A 1 98  ? -22.05212 -2.90431  25.22296 1.000 19.63746 ? 121 GLU A HG3  1 
ATOM   1518 N  N    . LEU A 1 99  ? -17.43355 -2.08816  24.31749 1.000 11.22250 ? 122 LEU A N    1 
ATOM   1519 C  CA   . LEU A 1 99  ? -16.13082 -1.71715  23.78135 1.000 11.31037 ? 122 LEU A CA   1 
ATOM   1520 C  C    . LEU A 1 99  ? -15.33322 -2.94647  23.37528 1.000 10.69215 ? 122 LEU A C    1 
ATOM   1521 O  O    . LEU A 1 99  ? -14.65235 -2.94084  22.34542 1.000 10.81863 ? 122 LEU A O    1 
ATOM   1522 C  CB   . LEU A 1 99  ? -15.38152 -0.85760  24.80779 1.000 11.91156 ? 122 LEU A CB   1 
ATOM   1523 C  CG   . LEU A 1 99  ? -15.97417 0.53198   25.03557 1.000 11.98512 ? 122 LEU A CG   1 
ATOM   1524 C  CD1  . LEU A 1 99  ? -15.53482 1.10907   26.36801 1.000 13.68921 ? 122 LEU A CD1  1 
ATOM   1525 C  CD2  . LEU A 1 99  ? -15.56303 1.46219   23.89929 1.000 13.22470 ? 122 LEU A CD2  1 
ATOM   1526 H  H    . LEU A 1 99  ? -17.54489 -1.89846  25.14888 1.000 13.46700 ? 122 LEU A H    1 
ATOM   1527 H  HA   . LEU A 1 99  ? -16.24579 -1.17990  22.98195 1.000 13.57244 ? 122 LEU A HA   1 
ATOM   1528 H  HB2  . LEU A 1 99  ? -15.38804 -1.32133  25.65973 1.000 14.29387 ? 122 LEU A HB2  1 
ATOM   1529 H  HB3  . LEU A 1 99  ? -14.46881 -0.73940  24.50138 1.000 14.29387 ? 122 LEU A HB3  1 
ATOM   1530 H  HG   . LEU A 1 99  ? -16.94127 0.45919   25.05331 1.000 14.38214 ? 122 LEU A HG   1 
ATOM   1531 H  HD11 . LEU A 1 99  ? -15.86935 2.01630   26.44494 1.000 16.42706 ? 122 LEU A HD11 1 
ATOM   1532 H  HD12 . LEU A 1 99  ? -15.89509 0.56189   27.08334 1.000 16.42706 ? 122 LEU A HD12 1 
ATOM   1533 H  HD13 . LEU A 1 99  ? -14.56564 1.10940   26.40784 1.000 16.42706 ? 122 LEU A HD13 1 
ATOM   1534 H  HD21 . LEU A 1 99  ? -16.04490 2.29950   23.98657 1.000 15.86964 ? 122 LEU A HD21 1 
ATOM   1535 H  HD22 . LEU A 1 99  ? -14.60796 1.62307   23.95274 1.000 15.86964 ? 122 LEU A HD22 1 
ATOM   1536 H  HD23 . LEU A 1 99  ? -15.78080 1.04192   23.05262 1.000 15.86964 ? 122 LEU A HD23 1 
ATOM   1537 N  N    . SER A 1 100 ? -15.41267 -4.00635  24.17545 1.000 11.20036 ? 123 SER A N    1 
ATOM   1538 C  CA   . SER A 1 100 ? -14.74141 -5.24484  23.80967 1.000 11.13071 ? 123 SER A CA   1 
ATOM   1539 C  C    . SER A 1 100 ? -15.28443 -5.79212  22.49157 1.000 11.10269 ? 123 SER A C    1 
ATOM   1540 O  O    . SER A 1 100 ? -14.51226 -6.17197  21.60174 1.000 11.38252 ? 123 SER A O    1 
ATOM   1541 C  CB   . SER A 1 100 ? -14.90408 -6.27148  24.93098 1.000 11.35194 ? 123 SER A CB   1 
ATOM   1542 O  OG   . SER A 1 100 ? -14.25916 -5.84695  26.12263 1.000 12.41592 ? 123 SER A OG   1 
ATOM   1543 H  H    . SER A 1 100 ? -15.84083 -4.03263  24.92083 1.000 13.44043 ? 123 SER A H    1 
ATOM   1544 H  HA   . SER A 1 100 ? -13.79425 -5.07023  23.69438 1.000 13.35685 ? 123 SER A HA   1 
ATOM   1545 H  HB2  . SER A 1 100 ? -15.84960 -6.39041  25.11193 1.000 13.62233 ? 123 SER A HB2  1 
ATOM   1546 H  HB3  . SER A 1 100 ? -14.51268 -7.11180  24.64539 1.000 13.62233 ? 123 SER A HB3  1 
ATOM   1547 H  HG   . SER A 1 100 ? -14.55716 -5.09815  26.35948 1.000 14.89910 ? 123 SER A HG   1 
ATOM   1548 N  N    . ALA A 1 101 ? -16.61157 -5.83917  22.35138 1.000 11.18154 ? 124 ALA A N    1 
ATOM   1549 C  CA   . ALA A 1 101 ? -17.22505 -6.31267  21.11681 1.000 12.18301 ? 124 ALA A CA   1 
ATOM   1550 C  C    . ALA A 1 101 ? -16.81746 -5.42745  19.94369 1.000 11.54739 ? 124 ALA A C    1 
ATOM   1551 O  O    . ALA A 1 101 ? -16.52004 -5.92567  18.85488 1.000 12.09278 ? 124 ALA A O    1 
ATOM   1552 C  CB   . ALA A 1 101 ? -18.74769 -6.34883  21.25347 1.000 12.23616 ? 124 ALA A CB   1 
ATOM   1553 H  H    . ALA A 1 101 ? -17.17557 -5.60266  22.95600 1.000 13.41785 ? 124 ALA A H    1 
ATOM   1554 H  HA   . ALA A 1 101 ? -16.92482 -7.21875  20.94424 1.000 14.61961 ? 124 ALA A HA   1 
ATOM   1555 H  HB1  . ALA A 1 101 ? -19.13097 -6.68422  20.42793 1.000 14.68339 ? 124 ALA A HB1  1 
ATOM   1556 H  HB2  . ALA A 1 101 ? -18.98486 -6.93387  21.98993 1.000 14.68339 ? 124 ALA A HB2  1 
ATOM   1557 H  HB3  . ALA A 1 101 ? -19.07058 -5.45080  21.42720 1.000 14.68339 ? 124 ALA A HB3  1 
ATOM   1558 N  N    . ALA A 1 102 ? -16.82195 -4.11059  20.14156 1.000 11.39216 ? 125 ALA A N    1 
ATOM   1559 C  CA   . ALA A 1 102 ? -16.46606 -3.20963  19.05257 1.000 10.86979 ? 125 ALA A CA   1 
ATOM   1560 C  C    . ALA A 1 102 ? -15.02065 -3.40041  18.61601 1.000 10.32279 ? 125 ALA A C    1 
ATOM   1561 O  O    . ALA A 1 102 ? -14.71778 -3.36963  17.41198 1.000 11.29042 ? 125 ALA A O    1 
ATOM   1562 C  CB   . ALA A 1 102 ? -16.73136 -1.76284  19.45980 1.000 12.05634 ? 125 ALA A CB   1 
ATOM   1563 H  H    . ALA A 1 102 ? -17.02321 -3.72202  20.88190 1.000 13.67059 ? 125 ALA A H    1 
ATOM   1564 H  HA   . ALA A 1 102 ? -17.02845 -3.40936  18.28791 1.000 13.04375 ? 125 ALA A HA   1 
ATOM   1565 H  HB1  . ALA A 1 102 ? -16.52259 -1.18101  18.71228 1.000 14.46760 ? 125 ALA A HB1  1 
ATOM   1566 H  HB2  . ALA A 1 102 ? -17.66620 -1.66901  19.70097 1.000 14.46760 ? 125 ALA A HB2  1 
ATOM   1567 H  HB3  . ALA A 1 102 ? -16.16997 -1.54043  20.21893 1.000 14.46760 ? 125 ALA A HB3  1 
ATOM   1568 N  N    . ALA A 1 103 ? -14.11102 -3.56513  19.57598 1.000 10.06081 ? 126 ALA A N    1 
ATOM   1569 C  CA   . ALA A 1 103 ? -12.70749 -3.78155  19.24391 1.000 10.01199 ? 126 ALA A CA   1 
ATOM   1570 C  C    . ALA A 1 103 ? -12.50149 -5.09394  18.50167 1.000 9.55772  ? 126 ALA A C    1 
ATOM   1571 O  O    . ALA A 1 103 ? -11.69192 -5.17583  17.56223 1.000 10.39519 ? 126 ALA A O    1 
ATOM   1572 C  CB   . ALA A 1 103 ? -11.86529 -3.76931  20.51388 1.000 10.52933 ? 126 ALA A CB   1 
ATOM   1573 H  H    . ALA A 1 103 ? -14.27969 -3.55583  20.41922 1.000 12.07298 ? 126 ALA A H    1 
ATOM   1574 H  HA   . ALA A 1 103 ? -12.41561 -3.05780  18.66781 1.000 12.01438 ? 126 ALA A HA   1 
ATOM   1575 H  HB1  . ALA A 1 103 ? -10.93179 -3.88035  20.27484 1.000 12.63519 ? 126 ALA A HB1  1 
ATOM   1576 H  HB2  . ALA A 1 103 ? -11.99177 -2.92185  20.96854 1.000 12.63519 ? 126 ALA A HB2  1 
ATOM   1577 H  HB3  . ALA A 1 103 ? -12.14872 -4.49812  21.08782 1.000 12.63519 ? 126 ALA A HB3  1 
ATOM   1578 N  N    . LEU A 1 104 ? -13.20998 -6.13645  18.90811 1.000 10.33463 ? 127 LEU A N    1 
ATOM   1579 C  CA   . LEU A 1 104 ? -12.98679 -7.45260  18.33561 1.000 9.65906  ? 127 LEU A CA   1 
ATOM   1580 C  C    . LEU A 1 104 ? -13.75764 -7.70477  17.05095 1.000 11.03659 ? 127 LEU A C    1 
ATOM   1581 O  O    . LEU A 1 104 ? -13.27069 -8.42836  16.17964 1.000 12.56359 ? 127 LEU A O    1 
ATOM   1582 C  CB   . LEU A 1 104 ? -13.34813 -8.52504  19.35725 1.000 10.56016 ? 127 LEU A CB   1 
ATOM   1583 C  CG   . LEU A 1 104 ? -12.44104 -8.59772  20.57481 1.000 11.03649 ? 127 LEU A CG   1 
ATOM   1584 C  CD1  . LEU A 1 104 ? -12.99280 -9.63663  21.53371 1.000 12.52249 ? 127 LEU A CD1  1 
ATOM   1585 C  CD2  . LEU A 1 104 ? -11.02216 -8.92733  20.18890 1.000 13.49028 ? 127 LEU A CD2  1 
ATOM   1586 H  H    . LEU A 1 104 ? -13.82258 -6.10744  19.51100 1.000 12.40156 ? 127 LEU A H    1 
ATOM   1587 H  HA   . LEU A 1 104 ? -12.04437 -7.53179  18.12002 1.000 11.59087 ? 127 LEU A HA   1 
ATOM   1588 H  HB2  . LEU A 1 104 ? -14.24768 -8.35151  19.67602 1.000 12.67220 ? 127 LEU A HB2  1 
ATOM   1589 H  HB3  . LEU A 1 104 ? -13.31283 -9.38897  18.91762 1.000 12.67220 ? 127 LEU A HB3  1 
ATOM   1590 H  HG   . LEU A 1 104 ? -12.41594 -7.73282  21.01325 1.000 13.24378 ? 127 LEU A HG   1 
ATOM   1591 H  HD11 . LEU A 1 104 ? -12.38754 -9.72451  22.28659 1.000 15.02699 ? 127 LEU A HD11 1 
ATOM   1592 H  HD12 . LEU A 1 104 ? -13.86591 -9.34872  21.84306 1.000 15.02699 ? 127 LEU A HD12 1 
ATOM   1593 H  HD13 . LEU A 1 104 ? -13.06940 -10.48520 21.07007 1.000 15.02699 ? 127 LEU A HD13 1 
ATOM   1594 H  HD21 . LEU A 1 104 ? -10.50023 -9.06743  20.99442 1.000 16.18833 ? 127 LEU A HD21 1 
ATOM   1595 H  HD22 . LEU A 1 104 ? -11.02076 -9.73349  19.64946 1.000 16.18833 ? 127 LEU A HD22 1 
ATOM   1596 H  HD23 . LEU A 1 104 ? -10.65343 -8.18830  19.68021 1.000 16.18833 ? 127 LEU A HD23 1 
ATOM   1597 N  N    . GLN A 1 105 ? -14.93782 -7.12233  16.90750 1.000 11.43957 ? 128 GLN A N    1 
ATOM   1598 C  CA   . GLN A 1 105 ? -15.81411 -7.43222  15.79282 1.000 11.81386 ? 128 GLN A CA   1 
ATOM   1599 C  C    . GLN A 1 105 ? -15.78212 -6.39775  14.69060 1.000 13.09788 ? 128 GLN A C    1 
ATOM   1600 O  O    . GLN A 1 105 ? -16.09391 -6.73619  13.54330 1.000 15.13069 ? 128 GLN A O    1 
ATOM   1601 C  CB   . GLN A 1 105 ? -17.24549 -7.64161  16.28678 1.000 13.72387 ? 128 GLN A CB   1 
ATOM   1602 C  CG   . GLN A 1 105 ? -17.32390 -8.79907  17.23794 1.000 14.42740 ? 128 GLN A CG   1 
ATOM   1603 C  CD   . GLN A 1 105 ? -18.70395 -9.05713  17.74249 1.000 15.93556 ? 128 GLN A CD   1 
ATOM   1604 O  OE1  . GLN A 1 105 ? -19.52559 -8.14297  17.84247 1.000 17.48846 ? 128 GLN A OE1  1 
ATOM   1605 N  NE2  . GLN A 1 105 ? -18.98228 -10.31318 18.07067 1.000 16.16211 ? 128 GLN A NE2  1 
ATOM   1606 H  H    . GLN A 1 105 ? -15.25724 -6.53655  17.45012 1.000 13.72749 ? 128 GLN A H    1 
ATOM   1607 H  HA   . GLN A 1 105 ? -15.52936 -8.26879  15.39286 1.000 14.17663 ? 128 GLN A HA   1 
ATOM   1608 H  HB2  . GLN A 1 105 ? -17.54703 -6.84346  16.74822 1.000 16.46864 ? 128 GLN A HB2  1 
ATOM   1609 H  HB3  . GLN A 1 105 ? -17.82371 -7.82576  15.53005 1.000 16.46864 ? 128 GLN A HB3  1 
ATOM   1610 H  HG2  . GLN A 1 105 ? -17.01872 -9.59990  16.78358 1.000 17.31288 ? 128 GLN A HG2  1 
ATOM   1611 H  HG3  . GLN A 1 105 ? -16.75691 -8.61537  18.00323 1.000 17.31288 ? 128 GLN A HG3  1 
ATOM   1612 H  HE21 . GLN A 1 105 ? -18.38148 -10.92276 17.98677 1.000 19.39453 ? 128 GLN A HE21 1 
ATOM   1613 H  HE22 . GLN A 1 105 ? -19.76337 -10.51717 18.36713 1.000 19.39453 ? 128 GLN A HE22 1 
ATOM   1614 N  N    . TYR A 1 106 ? -15.40689 -5.16267  15.01349 1.000 12.48707 ? 129 TYR A N    1 
ATOM   1615 C  CA   . TYR A 1 106 ? -15.30474 -4.07815  14.04470 1.000 13.00095 ? 129 TYR A CA   1 
ATOM   1616 C  C    . TYR A 1 106 ? -13.91774 -3.46393  14.03380 1.000 12.51252 ? 129 TYR A C    1 
ATOM   1617 O  O    . TYR A 1 106 ? -13.68384 -2.48758  13.31913 1.000 14.99794 ? 129 TYR A O    1 
ATOM   1618 C  CB   . TYR A 1 106 ? -16.36457 -3.00840  14.33068 1.000 14.12144 ? 129 TYR A CB   1 
ATOM   1619 C  CG   . TYR A 1 106 ? -17.74558 -3.56164  14.14496 1.000 16.24021 ? 129 TYR A CG   1 
ATOM   1620 C  CD1  . TYR A 1 106 ? -18.34875 -3.54785  12.90550 1.000 20.16436 ? 129 TYR A CD1  1 
ATOM   1621 C  CD2  . TYR A 1 106 ? -18.42759 -4.14725  15.20132 1.000 16.18774 ? 129 TYR A CD2  1 
ATOM   1622 C  CE1  . TYR A 1 106 ? -19.60779 -4.07738  12.72478 1.000 21.57632 ? 129 TYR A CE1  1 
ATOM   1623 C  CE2  . TYR A 1 106 ? -19.68311 -4.68518  15.02892 1.000 19.80200 ? 129 TYR A CE2  1 
ATOM   1624 C  CZ   . TYR A 1 106 ? -20.26765 -4.64893  13.78771 1.000 21.78611 ? 129 TYR A CZ   1 
ATOM   1625 O  OH   . TYR A 1 106 ? -21.53165 -5.17608  13.59743 1.000 25.66460 ? 129 TYR A OH   1 
ATOM   1626 H  H    . TYR A 1 106 ? -15.20002 -4.92162  15.81268 1.000 14.98448 ? 129 TYR A H    1 
ATOM   1627 H  HA   . TYR A 1 106 ? -15.48856 -4.41466  13.15371 1.000 15.60114 ? 129 TYR A HA   1 
ATOM   1628 H  HB2  . TYR A 1 106 ? -16.27566 -2.70252  15.24688 1.000 16.94573 ? 129 TYR A HB2  1 
ATOM   1629 H  HB3  . TYR A 1 106 ? -16.24573 -2.26455  13.71956 1.000 16.94573 ? 129 TYR A HB3  1 
ATOM   1630 H  HD1  . TYR A 1 106 ? -17.89951 -3.17590  12.18112 1.000 24.19723 ? 129 TYR A HD1  1 
ATOM   1631 H  HD2  . TYR A 1 106 ? -18.02953 -4.17705  16.04129 1.000 19.42529 ? 129 TYR A HD2  1 
ATOM   1632 H  HE1  . TYR A 1 106 ? -20.01018 -4.04846  11.88684 1.000 25.89158 ? 129 TYR A HE1  1 
ATOM   1633 H  HE2  . TYR A 1 106 ? -20.13127 -5.06980  15.74734 1.000 23.76239 ? 129 TYR A HE2  1 
ATOM   1634 H  HH   . TYR A 1 106 ? -21.75013 -5.64471  14.25943 1.000 30.79752 ? 129 TYR A HH   1 
ATOM   1635 N  N    . SER A 1 107 ? -12.99866 -3.98596  14.83884 1.000 11.34724 ? 130 SER A N    1 
ATOM   1636 C  CA   . SER A 1 107 ? -11.63856 -3.48473  14.90713 1.000 10.82970 ? 130 SER A CA   1 
ATOM   1637 C  C    . SER A 1 107 ? -11.58472 -2.02155  15.30749 1.000 9.99035  ? 130 SER A C    1 
ATOM   1638 O  O    . SER A 1 107 ? -10.67625 -1.30267  14.92722 1.000 10.99219 ? 130 SER A O    1 
ATOM   1639 C  CB   . SER A 1 107 ? -10.86777 -3.73580  13.61286 1.000 12.78183 ? 130 SER A CB   1 
ATOM   1640 O  OG   . SER A 1 107 ? -9.51416  -4.00592  13.94111 1.000 12.74611 ? 130 SER A OG   1 
ATOM   1641 H  H    . SER A 1 107 ? -13.14602 -4.64815  15.36741 1.000 13.61669 ? 130 SER A H    1 
ATOM   1642 H  HA   . SER A 1 107 ? -11.18143 -3.97911  15.60536 1.000 12.99564 ? 130 SER A HA   1 
ATOM   1643 H  HB2  . SER A 1 107 ? -11.24866 -4.49858  13.15028 1.000 15.33819 ? 130 SER A HB2  1 
ATOM   1644 H  HB3  . SER A 1 107 ? -10.91460 -2.94827  13.04850 1.000 15.33819 ? 130 SER A HB3  1 
ATOM   1645 H  HG   . SER A 1 107 ? -9.11831  -3.29175  14.13822 1.000 15.29533 ? 130 SER A HG   1 
ATOM   1646 N  N    . ASP A 1 108 ? -12.53060 -1.56639  16.11592 1.000 9.92803  ? 131 ASP A N    1 
ATOM   1647 C  CA   . ASP A 1 108 ? -12.60582 -0.15291  16.46815 1.000 10.20115 ? 131 ASP A CA   1 
ATOM   1648 C  C    . ASP A 1 108 ? -11.41322 0.28387   17.31920 1.000 10.07733 ? 131 ASP A C    1 
ATOM   1649 O  O    . ASP A 1 108 ? -11.08376 -0.33430  18.34226 1.000 10.33043 ? 131 ASP A O    1 
ATOM   1650 C  CB   . ASP A 1 108 ? -13.93677 0.11167   17.17931 1.000 10.50555 ? 131 ASP A CB   1 
ATOM   1651 C  CG   . ASP A 1 108 ? -14.23185 1.58468   17.37404 1.000 11.20411 ? 131 ASP A CG   1 
ATOM   1652 O  OD1  . ASP A 1 108 ? -13.47419 2.19994   18.14480 1.000 11.16155 ? 131 ASP A OD1  1 
ATOM   1653 O  OD2  . ASP A 1 108 ? -15.18190 2.09815   16.75225 1.000 13.05031 ? 131 ASP A OD2  1 
ATOM   1654 H  H    . ASP A 1 108 ? -13.14189 -2.05312  16.47512 1.000 11.91364 ? 131 ASP A H    1 
ATOM   1655 H  HA   . ASP A 1 108 ? -12.56920 0.38805   15.66384 1.000 12.24137 ? 131 ASP A HA   1 
ATOM   1656 H  HB2  . ASP A 1 108 ? -14.65586 -0.26823  16.65065 1.000 12.60666 ? 131 ASP A HB2  1 
ATOM   1657 H  HB3  . ASP A 1 108 ? -13.91285 -0.30502  18.05492 1.000 12.60666 ? 131 ASP A HB3  1 
ATOM   1658 N  N    . ASN A 1 109 ? -10.73408 1.34116   16.86550 1.000 9.85259  ? 132 ASN A N    1 
ATOM   1659 C  CA   . ASN A 1 109 ? -9.52276  1.78069   17.53245 1.000 10.19096 ? 132 ASN A CA   1 
ATOM   1660 C  C    . ASN A 1 109 ? -9.80138  2.58149   18.79374 1.000 9.91594  ? 132 ASN A C    1 
ATOM   1661 O  O    . ASN A 1 109 ? -8.98387  2.55261   19.71557 1.000 10.24075 ? 132 ASN A O    1 
ATOM   1662 C  CB   . ASN A 1 109 ? -8.66070  2.62867   16.59829 1.000 10.32014 ? 132 ASN A CB   1 
ATOM   1663 C  CG   . ASN A 1 109 ? -7.74890  1.80124   15.72878 1.000 11.91056 ? 132 ASN A CG   1 
ATOM   1664 O  OD1  . ASN A 1 109 ? -7.59320  0.61064   15.93707 1.000 12.62010 ? 132 ASN A OD1  1 
ATOM   1665 N  ND2  . ASN A 1 109 ? -7.12574  2.44256   14.73682 1.000 13.66296 ? 132 ASN A ND2  1 
ATOM   1666 H  H    . ASN A 1 109 ? -10.95649 1.81143   16.18068 1.000 11.82311 ? 132 ASN A H    1 
ATOM   1667 H  HA   . ASN A 1 109 ? -9.02630  0.98311   17.77389 1.000 12.22915 ? 132 ASN A HA   1 
ATOM   1668 H  HB2  . ASN A 1 109 ? -9.24002  3.14606   16.01726 1.000 12.38417 ? 132 ASN A HB2  1 
ATOM   1669 H  HB3  . ASN A 1 109 ? -8.10875  3.22262   17.13071 1.000 12.38417 ? 132 ASN A HB3  1 
ATOM   1670 H  HD21 . ASN A 1 109 ? -6.59513  2.01320   14.21364 1.000 16.39555 ? 132 ASN A HD21 1 
ATOM   1671 H  HD22 . ASN A 1 109 ? -7.25505  3.28489   14.62123 1.000 16.39555 ? 132 ASN A HD22 1 
ATOM   1672 N  N    . VAL A 1 110 ? -10.90794 3.32830   18.84355 1.000 10.00612 ? 133 VAL A N    1 
ATOM   1673 C  CA   . VAL A 1 110 ? -11.28504 3.98780   20.09481 1.000 10.13530 ? 133 VAL A CA   1 
ATOM   1674 C  C    . VAL A 1 110 ? -11.56670 2.94685   21.15476 1.000 9.91570  ? 133 VAL A C    1 
ATOM   1675 O  O    . VAL A 1 110 ? -11.11929 3.05655   22.30131 1.000 10.09954 ? 133 VAL A O    1 
ATOM   1676 C  CB   . VAL A 1 110 ? -12.50398 4.90416   19.90110 1.000 10.67021 ? 133 VAL A CB   1 
ATOM   1677 C  CG1  . VAL A 1 110 ? -12.90166 5.50765   21.23452 1.000 11.59363 ? 133 VAL A CG1  1 
ATOM   1678 C  CG2  . VAL A 1 110 ? -12.21901 5.98354   18.89423 1.000 12.37771 ? 133 VAL A CG2  1 
ATOM   1679 H  H    . VAL A 1 110 ? -11.44323 3.46542   18.18456 1.000 12.00735 ? 133 VAL A H    1 
ATOM   1680 H  HA   . VAL A 1 110 ? -10.54059 4.54303   20.37485 1.000 12.16236 ? 133 VAL A HA   1 
ATOM   1681 H  HB   . VAL A 1 110 ? -13.24367 4.37853   19.55835 1.000 12.80425 ? 133 VAL A HB   1 
ATOM   1682 H  HG11 . VAL A 1 110 ? -13.57142 6.19293   21.08382 1.000 13.91236 ? 133 VAL A HG11 1 
ATOM   1683 H  HG12 . VAL A 1 110 ? -13.26467 4.80934   21.80151 1.000 13.91236 ? 133 VAL A HG12 1 
ATOM   1684 H  HG13 . VAL A 1 110 ? -12.11730 5.89765   21.65114 1.000 13.91236 ? 133 VAL A HG13 1 
ATOM   1685 H  HG21 . VAL A 1 110 ? -13.02962 6.49345   18.73992 1.000 14.85325 ? 133 VAL A HG21 1 
ATOM   1686 H  HG22 . VAL A 1 110 ? -11.52411 6.56420   19.24186 1.000 14.85325 ? 133 VAL A HG22 1 
ATOM   1687 H  HG23 . VAL A 1 110 ? -11.92372 5.57320   18.06639 1.000 14.85325 ? 133 VAL A HG23 1 
ATOM   1688 N  N    . ALA A 1 111 ? -12.29449 1.90665   20.77962 1.000 9.77909  ? 134 ALA A N    1 
ATOM   1689 C  CA   . ALA A 1 111 ? -12.61144 0.84177   21.71610 1.000 9.24496  ? 134 ALA A CA   1 
ATOM   1690 C  C    . ALA A 1 111 ? -11.33879 0.22573   22.27212 1.000 9.54286  ? 134 ALA A C    1 
ATOM   1691 O  O    . ALA A 1 111 ? -11.20476 0.02251   23.48682 1.000 9.67357  ? 134 ALA A O    1 
ATOM   1692 C  CB   . ALA A 1 111 ? -13.49114 -0.20788  21.02616 1.000 9.90957  ? 134 ALA A CB   1 
ATOM   1693 H  H    . ALA A 1 111 ? -12.61673 1.79273   19.99045 1.000 11.73491 ? 134 ALA A H    1 
ATOM   1694 H  HA   . ALA A 1 111 ? -13.11665 1.20099   22.46217 1.000 11.09395 ? 134 ALA A HA   1 
ATOM   1695 H  HB1  . ALA A 1 111 ? -13.69541 -0.91404  21.65902 1.000 11.89148 ? 134 ALA A HB1  1 
ATOM   1696 H  HB2  . ALA A 1 111 ? -14.31103 0.21496   20.72634 1.000 11.89148 ? 134 ALA A HB2  1 
ATOM   1697 H  HB3  . ALA A 1 111 ? -13.01046 -0.57303  20.26688 1.000 11.89148 ? 134 ALA A HB3  1 
ATOM   1698 N  N    . MET A 1 112 ? -10.38045 -0.07882  21.39721 1.000 9.53418  ? 135 MET A N    1 
ATOM   1699 C  CA   . MET A 1 112 ? -9.08892  -0.57674  21.85636 1.000 8.98866  ? 135 MET A CA   1 
ATOM   1700 C  C    . MET A 1 112 ? -8.45178  0.37098   22.87281 1.000 9.15587  ? 135 MET A C    1 
ATOM   1701 O  O    . MET A 1 112 ? -7.94431  -0.06423  23.91465 1.000 9.82778  ? 135 MET A O    1 
ATOM   1702 C  CB   . MET A 1 112 ? -8.17600  -0.82768  20.64983 1.000 9.18060  ? 135 MET A CB   1 
ATOM   1703 C  CG   . MET A 1 112 ? -6.73919  -1.17784  20.99894 1.000 9.49548  ? 135 MET A CG   1 
ATOM   1704 S  SD   . MET A 1 112 ? -6.61412  -2.67246  22.01579 1.000 9.76917  ? 135 MET A SD   1 
ATOM   1705 C  CE   . MET A 1 112 ? -5.01832  -3.29742  21.47357 1.000 10.38016 ? 135 MET A CE   1 
ATOM   1706 H  H    . MET A 1 112 ? -10.45287 -0.00667  20.54331 1.000 11.44102 ? 135 MET A H    1 
ATOM   1707 H  HA   . MET A 1 112 ? -9.21894  -1.42944  22.30008 1.000 10.78639 ? 135 MET A HA   1 
ATOM   1708 H  HB2  . MET A 1 112 ? -8.53981  -1.56638  20.13713 1.000 11.01672 ? 135 MET A HB2  1 
ATOM   1709 H  HB3  . MET A 1 112 ? -8.15657  -0.02443  20.10641 1.000 11.01672 ? 135 MET A HB3  1 
ATOM   1710 H  HG2  . MET A 1 112 ? -6.24211  -1.32903  20.17982 1.000 11.39457 ? 135 MET A HG2  1 
ATOM   1711 H  HG3  . MET A 1 112 ? -6.34571  -0.44296  21.49495 1.000 11.39457 ? 135 MET A HG3  1 
ATOM   1712 H  HE1  . MET A 1 112 ? -4.81821  -4.11421  21.95701 1.000 12.45619 ? 135 MET A HE1  1 
ATOM   1713 H  HE2  . MET A 1 112 ? -5.05678  -3.47768  20.52124 1.000 12.45619 ? 135 MET A HE2  1 
ATOM   1714 H  HE3  . MET A 1 112 ? -4.33891  -2.62976  21.65668 1.000 12.45619 ? 135 MET A HE3  1 
ATOM   1715 N  N    . ASN A 1 113 ? -8.42701  1.66026   22.56587 1.000 9.61430  ? 136 ASN A N    1 
ATOM   1716 C  CA   . ASN A 1 113 ? -7.81075  2.59743   23.48825 1.000 9.94542  ? 136 ASN A CA   1 
ATOM   1717 C  C    . ASN A 1 113 ? -8.52102  2.60394   24.83711 1.000 10.83599 ? 136 ASN A C    1 
ATOM   1718 O  O    . ASN A 1 113 ? -7.86933  2.77352   25.87778 1.000 11.01999 ? 136 ASN A O    1 
ATOM   1719 C  CB   . ASN A 1 113 ? -7.77656  4.00820   22.90601 1.000 9.49019  ? 136 ASN A CB   1 
ATOM   1720 C  CG   . ASN A 1 113 ? -6.61006  4.19175   21.95108 1.000 10.05424 ? 136 ASN A CG   1 
ATOM   1721 O  OD1  . ASN A 1 113 ? -5.70650  3.35474   21.90323 1.000 11.20077 ? 136 ASN A OD1  1 
ATOM   1722 N  ND2  . ASN A 1 113 ? -6.61905  5.27797   21.19905 1.000 11.52286 ? 136 ASN A ND2  1 
ATOM   1723 H  H    . ASN A 1 113 ? -8.75121  2.00840   21.84942 1.000 11.53715 ? 136 ASN A H    1 
ATOM   1724 H  HA   . ASN A 1 113 ? -6.89296  2.31410   23.62350 1.000 11.93451 ? 136 ASN A HA   1 
ATOM   1725 H  HB2  . ASN A 1 113 ? -8.59854  4.17350   22.41822 1.000 11.38823 ? 136 ASN A HB2  1 
ATOM   1726 H  HB3  . ASN A 1 113 ? -7.68390  4.65028   23.62715 1.000 11.38823 ? 136 ASN A HB3  1 
ATOM   1727 H  HD21 . ASN A 1 113 ? -5.97805  5.42208   20.64412 1.000 13.82744 ? 136 ASN A HD21 1 
ATOM   1728 H  HD22 . ASN A 1 113 ? -7.26590  5.84091   21.26446 1.000 13.82744 ? 136 ASN A HD22 1 
ATOM   1729 N  N    . LYS A 1 114 ? -9.85232  2.45277   24.85305 1.000 9.62816  ? 137 LYS A N    1 
ATOM   1730 C  CA   . LYS A 1 114 ? -10.55899 2.40124   26.13289 1.000 10.47267 ? 137 LYS A CA   1 
ATOM   1731 C  C    . LYS A 1 114 ? -10.22330 1.13425   26.91175 1.000 10.86280 ? 137 LYS A C    1 
ATOM   1732 O  O    . LYS A 1 114 ? -10.12631 1.16301   28.14682 1.000 11.10199 ? 137 LYS A O    1 
ATOM   1733 C  CB   . LYS A 1 114 ? -12.05990 2.54896   25.92677 1.000 9.95534  ? 137 LYS A CB   1 
ATOM   1734 C  CG   . LYS A 1 114 ? -12.47198 3.90550   25.35500 1.000 10.85421 ? 137 LYS A CG   1 
ATOM   1735 C  CD   . LYS A 1 114 ? -12.00298 5.06290   26.22105 1.000 11.27332 ? 137 LYS A CD   1 
ATOM   1736 C  CE   . LYS A 1 114 ? -12.55604 6.38314   25.71138 1.000 12.35748 ? 137 LYS A CE   1 
ATOM   1737 N  NZ   . LYS A 1 114 ? -12.06201 7.52885   26.50575 1.000 14.78955 ? 137 LYS A NZ   1 
ATOM   1738 H  H    . LYS A 1 114 ? -10.35222 2.38015   24.15704 1.000 11.55379 ? 137 LYS A H    1 
ATOM   1739 H  HA   . LYS A 1 114 ? -10.27103 3.15522   26.67093 1.000 12.56720 ? 137 LYS A HA   1 
ATOM   1740 H  HB2  . LYS A 1 114 ? -12.35872 1.86381   25.30857 1.000 11.94641 ? 137 LYS A HB2  1 
ATOM   1741 H  HB3  . LYS A 1 114 ? -12.50431 2.44069   26.78215 1.000 11.94641 ? 137 LYS A HB3  1 
ATOM   1742 H  HG2  . LYS A 1 114 ? -12.08151 4.01115   24.47337 1.000 13.02506 ? 137 LYS A HG2  1 
ATOM   1743 H  HG3  . LYS A 1 114 ? -13.43937 3.94555   25.29636 1.000 13.02506 ? 137 LYS A HG3  1 
ATOM   1744 H  HD2  . LYS A 1 114 ? -12.31189 4.93152   27.13111 1.000 13.52799 ? 137 LYS A HD2  1 
ATOM   1745 H  HD3  . LYS A 1 114 ? -11.03422 5.10840   26.20283 1.000 13.52799 ? 137 LYS A HD3  1 
ATOM   1746 H  HE2  . LYS A 1 114 ? -12.28081 6.51105   24.79009 1.000 14.82897 ? 137 LYS A HE2  1 
ATOM   1747 H  HE3  . LYS A 1 114 ? -13.52419 6.36822   25.76938 1.000 14.82897 ? 137 LYS A HE3  1 
ATOM   1748 H  HZ1  . LYS A 1 114 ? -12.73376 7.89774   26.95827 1.000 17.74746 ? 137 LYS A HZ1  1 
ATOM   1749 H  HZ2  . LYS A 1 114 ? -11.44165 7.25475   27.08205 1.000 17.74746 ? 137 LYS A HZ2  1 
ATOM   1750 H  HZ3  . LYS A 1 114 ? -11.70561 8.14141   25.96738 1.000 17.74746 ? 137 LYS A HZ3  1 
ATOM   1751 N  N    . LEU A 1 115 ? -10.06560 0.01441   26.22324 1.000 10.34050 ? 138 LEU A N    1 
ATOM   1752 C  CA   . LEU A 1 115 ? -9.67508  -1.20792  26.90981 1.000 11.01206 ? 138 LEU A CA   1 
ATOM   1753 C  C    . LEU A 1 115 ? -8.28134  -1.05308  27.48916 1.000 10.53439 ? 138 LEU A C    1 
ATOM   1754 O  O    . LEU A 1 115 ? -8.02839  -1.39257  28.64994 1.000 11.82645 ? 138 LEU A O    1 
ATOM   1755 C  CB   . LEU A 1 115 ? -9.70081  -2.39371  25.94756 1.000 10.74836 ? 138 LEU A CB   1 
ATOM   1756 C  CG   . LEU A 1 115 ? -11.03413 -2.72452  25.28111 1.000 11.23800 ? 138 LEU A CG   1 
ATOM   1757 C  CD1  . LEU A 1 115 ? -10.84441 -3.84829  24.26032 1.000 12.31770 ? 138 LEU A CD1  1 
ATOM   1758 C  CD2  . LEU A 1 115 ? -12.10426 -3.09131  26.31128 1.000 13.87559 ? 138 LEU A CD2  1 
ATOM   1759 H  H    . LEU A 1 115 ? -10.17600 -0.06489  25.37405 1.000 12.40860 ? 138 LEU A H    1 
ATOM   1760 H  HA   . LEU A 1 115 ? -10.30895 -1.38431  27.62255 1.000 13.21448 ? 138 LEU A HA   1 
ATOM   1761 H  HB2  . LEU A 1 115 ? -9.06717  -2.21294  25.23572 1.000 12.89803 ? 138 LEU A HB2  1 
ATOM   1762 H  HB3  . LEU A 1 115 ? -9.42894  -3.18325  26.44113 1.000 12.89803 ? 138 LEU A HB3  1 
ATOM   1763 H  HG   . LEU A 1 115 ? -11.35410 -1.93649  24.81472 1.000 13.48560 ? 138 LEU A HG   1 
ATOM   1764 H  HD11 . LEU A 1 115 ? -11.69887 -4.04618  23.84604 1.000 14.78124 ? 138 LEU A HD11 1 
ATOM   1765 H  HD12 . LEU A 1 115 ? -10.20926 -3.55907  23.58664 1.000 14.78124 ? 138 LEU A HD12 1 
ATOM   1766 H  HD13 . LEU A 1 115 ? -10.50761 -4.63547  24.71618 1.000 14.78124 ? 138 LEU A HD13 1 
ATOM   1767 H  HD21 . LEU A 1 115 ? -12.94648 -3.23833  25.85308 1.000 16.65071 ? 138 LEU A HD21 1 
ATOM   1768 H  HD22 . LEU A 1 115 ? -11.83361 -3.90001  26.77353 1.000 16.65071 ? 138 LEU A HD22 1 
ATOM   1769 H  HD23 . LEU A 1 115 ? -12.19532 -2.36273  26.94514 1.000 16.65071 ? 138 LEU A HD23 1 
ATOM   1770 N  N    . ILE A 1 116 ? -7.36784  -0.52462  26.69096 1.000 10.26586 ? 139 ILE A N    1 
ATOM   1771 C  CA   . ILE A 1 116 ? -6.00826  -0.27970  27.16024 1.000 10.39679 ? 139 ILE A CA   1 
ATOM   1772 C  C    . ILE A 1 116 ? -6.03200  0.61753   28.38657 1.000 11.85766 ? 139 ILE A C    1 
ATOM   1773 O  O    . ILE A 1 116 ? -5.38992  0.33171   29.40151 1.000 11.96831 ? 139 ILE A O    1 
ATOM   1774 C  CB   . ILE A 1 116 ? -5.15038  0.33393   26.03733 1.000 10.54014 ? 139 ILE A CB   1 
ATOM   1775 C  CG1  . ILE A 1 116 ? -4.86307  -0.67521  24.92981 1.000 10.76130 ? 139 ILE A CG1  1 
ATOM   1776 C  CG2  . ILE A 1 116 ? -3.82969  0.85228   26.61611 1.000 11.82202 ? 139 ILE A CG2  1 
ATOM   1777 C  CD1  . ILE A 1 116 ? -4.20822  -0.05885  23.69467 1.000 10.86789 ? 139 ILE A CD1  1 
ATOM   1778 H  H    . ILE A 1 116 ? -7.50544  -0.29761  25.87296 1.000 12.31903 ? 139 ILE A H    1 
ATOM   1779 H  HA   . ILE A 1 116 ? -5.61226  -1.12903  27.41067 1.000 12.47614 ? 139 ILE A HA   1 
ATOM   1780 H  HB   . ILE A 1 116 ? -5.65498  1.06687   25.65123 1.000 12.64817 ? 139 ILE A HB   1 
ATOM   1781 H  HG12 . ILE A 1 116 ? -4.26395  -1.35559  25.27484 1.000 12.91356 ? 139 ILE A HG12 1 
ATOM   1782 H  HG13 . ILE A 1 116 ? -5.69944  -1.07996  24.65130 1.000 12.91356 ? 139 ILE A HG13 1 
ATOM   1783 H  HG21 . ILE A 1 116 ? -3.25585  1.13703   25.88774 1.000 14.18643 ? 139 ILE A HG21 1 
ATOM   1784 H  HG22 . ILE A 1 116 ? -4.01486  1.60154   27.20366 1.000 14.18643 ? 139 ILE A HG22 1 
ATOM   1785 H  HG23 . ILE A 1 116 ? -3.40179  0.13875   27.11479 1.000 14.18643 ? 139 ILE A HG23 1 
ATOM   1786 H  HD11 . ILE A 1 116 ? -4.23260  -0.70287  22.96972 1.000 13.04147 ? 139 ILE A HD11 1 
ATOM   1787 H  HD12 . ILE A 1 116 ? -4.69716  0.74042   23.44366 1.000 13.04147 ? 139 ILE A HD12 1 
ATOM   1788 H  HD13 . ILE A 1 116 ? -3.28884  0.16810   23.90473 1.000 13.04147 ? 139 ILE A HD13 1 
ATOM   1789 N  N    . ALA A 1 117 ? -6.76388  1.72450   28.30100 1.000 12.23041 ? 140 ALA A N    1 
ATOM   1790 C  CA   . ALA A 1 117 ? -6.77537  2.66203   29.41304 1.000 13.50376 ? 140 ALA A CA   1 
ATOM   1791 C  C    . ALA A 1 117 ? -7.31022  2.00024   30.66718 1.000 13.16741 ? 140 ALA A C    1 
ATOM   1792 O  O    . ALA A 1 117 ? -6.78144  2.21591   31.76483 1.000 14.31399 ? 140 ALA A O    1 
ATOM   1793 C  CB   . ALA A 1 117 ? -7.60802  3.89053   29.06676 1.000 14.23899 ? 140 ALA A CB   1 
ATOM   1794 H  H    . ALA A 1 117 ? -7.24931  1.94906   27.62755 1.000 14.67649 ? 140 ALA A H    1 
ATOM   1795 H  HA   . ALA A 1 117 ? -5.86703  2.95819   29.58068 1.000 16.20452 ? 140 ALA A HA   1 
ATOM   1796 H  HB1  . ALA A 1 117 ? -7.58499  4.50853   29.81405 1.000 17.08679 ? 140 ALA A HB1  1 
ATOM   1797 H  HB2  . ALA A 1 117 ? -7.23504  4.31247   28.27698 1.000 17.08679 ? 140 ALA A HB2  1 
ATOM   1798 H  HB3  . ALA A 1 117 ? -8.52167  3.61433   28.89399 1.000 17.08679 ? 140 ALA A HB3  1 
ATOM   1799 N  N    A HIS A 1 118 ? -8.38218  1.22607   30.53570 0.560 12.91917 ? 141 HIS A N    1 
ATOM   1800 N  N    B HIS A 1 118 ? -8.34805  1.16294   30.53089 0.440 13.20098 ? 141 HIS A N    1 
ATOM   1801 C  CA   A HIS A 1 118 ? -8.98532  0.67181   31.73044 0.560 15.03218 ? 141 HIS A CA   1 
ATOM   1802 C  CA   B HIS A 1 118 ? -9.06173  0.60158   31.67711 0.440 14.78484 ? 141 HIS A CA   1 
ATOM   1803 C  C    A HIS A 1 118 ? -8.01083  -0.23262  32.46946 0.560 14.37007 ? 141 HIS A C    1 
ATOM   1804 C  C    B HIS A 1 118 ? -8.41024  -0.63702  32.27816 0.440 15.92917 ? 141 HIS A C    1 
ATOM   1805 O  O    A HIS A 1 118 ? -7.93214  -0.19763  33.70395 0.560 14.48145 ? 141 HIS A O    1 
ATOM   1806 O  O    B HIS A 1 118 ? -8.93901  -1.18954  33.25688 0.440 16.96885 ? 141 HIS A O    1 
ATOM   1807 C  CB   A HIS A 1 118 ? -10.24938 -0.10261  31.41218 0.560 17.86720 ? 141 HIS A CB   1 
ATOM   1808 C  CB   B HIS A 1 118 ? -10.51636 0.30592   31.31504 0.440 15.38909 ? 141 HIS A CB   1 
ATOM   1809 C  CG   A HIS A 1 118 ? -10.90325 -0.63846  32.63999 0.560 21.93783 ? 141 HIS A CG   1 
ATOM   1810 C  CG   B HIS A 1 118 ? -11.41597 1.47825   31.51243 0.440 16.31752 ? 141 HIS A CG   1 
ATOM   1811 N  ND1  A HIS A 1 118 ? -11.72846 0.13095   33.42957 0.560 22.81058 ? 141 HIS A ND1  1 
ATOM   1812 N  ND1  B HIS A 1 118 ? -11.55864 2.47384   30.57250 0.440 17.90560 ? 141 HIS A ND1  1 
ATOM   1813 C  CD2  A HIS A 1 118 ? -10.79377 -1.83563  33.26298 0.560 24.52674 ? 141 HIS A CD2  1 
ATOM   1814 C  CD2  B HIS A 1 118 ? -12.18438 1.83991   32.56536 0.440 16.47946 ? 141 HIS A CD2  1 
ATOM   1815 C  CE1  A HIS A 1 118 ? -12.12720 -0.57775  34.46938 0.560 24.14393 ? 141 HIS A CE1  1 
ATOM   1816 C  CE1  B HIS A 1 118 ? -12.39072 3.39111   31.03179 0.440 16.59248 ? 141 HIS A CE1  1 
ATOM   1817 N  NE2  A HIS A 1 118 ? -11.57496 -1.77693  34.39019 0.560 25.17513 ? 141 HIS A NE2  1 
ATOM   1818 N  NE2  B HIS A 1 118 ? -12.78027 3.03197   32.24092 0.440 16.72915 ? 141 HIS A NE2  1 
ATOM   1819 H  H    A HIS A 1 118 ? -8.76226  1.01666   29.79321 0.560 15.50301 ? 141 HIS A H    1 
ATOM   1820 H  H    B HIS A 1 118 ? -8.65930  0.90348   29.77233 0.440 15.84118 ? 141 HIS A H    1 
ATOM   1821 H  HA   A HIS A 1 118 ? -9.23133  1.41629   32.30151 0.560 18.03861 ? 141 HIS A HA   1 
ATOM   1822 H  HA   B HIS A 1 118 ? -9.06455  1.27778   32.37255 0.440 17.74181 ? 141 HIS A HA   1 
ATOM   1823 H  HB2  A HIS A 1 118 ? -10.87871 0.48512   30.96562 0.560 21.44064 ? 141 HIS A HB2  1 
ATOM   1824 H  HB2  B HIS A 1 118 ? -10.56202 0.04761   30.38119 0.440 18.46691 ? 141 HIS A HB2  1 
ATOM   1825 H  HB3  A HIS A 1 118 ? -10.02769 -0.85067  30.83586 0.560 21.44064 ? 141 HIS A HB3  1 
ATOM   1826 H  HB3  B HIS A 1 118 ? -10.83952 -0.41691  31.87538 0.440 18.46691 ? 141 HIS A HB3  1 
ATOM   1827 H  HD1  A HIS A 1 118 ? -11.94968 0.94655   33.27000 0.560 27.37270 ? 141 HIS A HD1  1 
ATOM   1828 H  HD2  A HIS A 1 118 ? -10.28509 -2.56109  32.98041 0.560 29.43209 ? 141 HIS A HD2  1 
ATOM   1829 H  HD2  B HIS A 1 118 ? -12.28901 1.36863   33.36024 0.440 19.77535 ? 141 HIS A HD2  1 
ATOM   1830 H  HE1  A HIS A 1 118 ? -12.69835 -0.28425  35.14210 0.560 28.97271 ? 141 HIS A HE1  1 
ATOM   1831 H  HE1  B HIS A 1 118 ? -12.65687 4.15929   30.58017 0.440 19.91098 ? 141 HIS A HE1  1 
ATOM   1832 H  HE2  B HIS A 1 118 ? -13.32021 3.47384   32.74373 0.440 20.07498 ? 141 HIS A HE2  1 
ATOM   1833 N  N    . VAL A 1 119 ? -7.28070  -1.08162  31.74280 1.000 14.42082 ? 142 VAL A N    1 
ATOM   1834 C  CA   . VAL A 1 119 ? -6.42019  -2.02471  32.44940 1.000 17.33814 ? 142 VAL A CA   1 
ATOM   1835 C  C    . VAL A 1 119 ? -5.13204  -1.39593  32.91600 1.000 17.78116 ? 142 VAL A C    1 
ATOM   1836 O  O    . VAL A 1 119 ? -4.41028  -2.01839  33.70769 1.000 19.39307 ? 142 VAL A O    1 
ATOM   1837 C  CB   . VAL A 1 119 ? -6.15457  -3.31245  31.65413 1.000 20.69787 ? 142 VAL A CB   1 
ATOM   1838 C  CG1  . VAL A 1 119 ? -7.46769  -3.99523  31.31641 1.000 22.59581 ? 142 VAL A CG1  1 
ATOM   1839 C  CG2  . VAL A 1 119 ? -5.36720  -3.00773  30.43270 1.000 18.32171 ? 142 VAL A CG2  1 
ATOM   1840 H  H    A VAL A 1 119 ? -7.26814  -1.12736  30.88411 0.560 17.30498 ? 142 VAL A H    1 
ATOM   1841 H  H    B VAL A 1 119 ? -6.98820  -0.85148  30.96751 0.440 17.30498 ? 142 VAL A H    1 
ATOM   1842 H  HA   . VAL A 1 119 ? -6.90101  -2.31248  33.24117 1.000 20.80577 ? 142 VAL A HA   1 
ATOM   1843 H  HB   . VAL A 1 119 ? -5.63220  -3.92770  32.19218 1.000 24.83744 ? 142 VAL A HB   1 
ATOM   1844 H  HG11 . VAL A 1 119 ? -7.28441  -4.79060  30.79230 1.000 27.11497 ? 142 VAL A HG11 1 
ATOM   1845 H  HG12 . VAL A 1 119 ? -7.91816  -4.23853  32.14029 1.000 27.11497 ? 142 VAL A HG12 1 
ATOM   1846 H  HG13 . VAL A 1 119 ? -8.01998  -3.38267  30.80588 1.000 27.11497 ? 142 VAL A HG13 1 
ATOM   1847 H  HG21 . VAL A 1 119 ? -5.21951  -3.82952  29.93899 1.000 21.98605 ? 142 VAL A HG21 1 
ATOM   1848 H  HG22 . VAL A 1 119 ? -5.86305  -2.37811  29.88624 1.000 21.98605 ? 142 VAL A HG22 1 
ATOM   1849 H  HG23 . VAL A 1 119 ? -4.51667  -2.62113  30.69353 1.000 21.98605 ? 142 VAL A HG23 1 
ATOM   1850 N  N    . GLY A 1 120 ? -4.83130  -0.17824  32.47346 1.000 16.74529 ? 143 GLY A N    1 
ATOM   1851 C  CA   . GLY A 1 120 ? -3.69228  0.53874   33.01571 1.000 17.61112 ? 143 GLY A CA   1 
ATOM   1852 C  C    . GLY A 1 120 ? -2.65243  0.93880   31.99635 1.000 18.90198 ? 143 GLY A C    1 
ATOM   1853 O  O    . GLY A 1 120 ? -1.59740  1.43790   32.37558 1.000 24.38927 ? 143 GLY A O    1 
ATOM   1854 H  H    . GLY A 1 120 ? -5.26870  0.24618   31.86670 1.000 20.09435 ? 143 GLY A H    1 
ATOM   1855 H  HA2  . GLY A 1 120 ? -4.00987  1.34747   33.44697 1.000 21.13334 ? 143 GLY A HA2  1 
ATOM   1856 H  HA3  . GLY A 1 120 ? -3.25742  -0.02195  33.67709 1.000 21.13334 ? 143 GLY A HA3  1 
ATOM   1857 N  N    . GLY A 1 121 ? -2.92140  0.75816   30.71187 1.000 14.62618 ? 144 GLY A N    1 
ATOM   1858 C  CA   . GLY A 1 121 ? -1.97972  1.13325   29.69022 1.000 13.83536 ? 144 GLY A CA   1 
ATOM   1859 C  C    . GLY A 1 121 ? -1.36399  -0.06875  29.00696 1.000 11.96050 ? 144 GLY A C    1 
ATOM   1860 O  O    . GLY A 1 121 ? -1.57940  -1.22428  29.39400 1.000 12.88085 ? 144 GLY A O    1 
ATOM   1861 H  H    . GLY A 1 121 ? -3.65115  0.41655   30.41125 1.000 17.55141 ? 144 GLY A H    1 
ATOM   1862 H  HA2  . GLY A 1 121 ? -2.43030  1.66924   29.01896 1.000 16.60243 ? 144 GLY A HA2  1 
ATOM   1863 H  HA3  . GLY A 1 121 ? -1.26696  1.65799   30.08712 1.000 16.60243 ? 144 GLY A HA3  1 
ATOM   1864 N  N    . PRO A 1 122 ? -0.60006  0.18311   27.93914 1.000 12.22799 ? 145 PRO A N    1 
ATOM   1865 C  CA   . PRO A 1 122 ? -0.01759  -0.93882  27.18088 1.000 11.99097 ? 145 PRO A CA   1 
ATOM   1866 C  C    . PRO A 1 122 ? 0.80535   -1.88300  28.03206 1.000 11.75952 ? 145 PRO A C    1 
ATOM   1867 O  O    . PRO A 1 122 ? 0.71271   -3.10117  27.84797 1.000 13.02106 ? 145 PRO A O    1 
ATOM   1868 C  CB   . PRO A 1 122 ? 0.80248   -0.22767  26.09539 1.000 12.64489 ? 145 PRO A CB   1 
ATOM   1869 C  CG   . PRO A 1 122 ? 0.07421   1.09997   25.91333 1.000 12.77689 ? 145 PRO A CG   1 
ATOM   1870 C  CD   . PRO A 1 122 ? -0.30407  1.48804   27.31796 1.000 12.65953 ? 145 PRO A CD   1 
ATOM   1871 H  HA   . PRO A 1 122 ? -0.71852  -1.45360  26.75122 1.000 14.38916 ? 145 PRO A HA   1 
ATOM   1872 H  HB2  . PRO A 1 122 ? 1.71407   -0.09141  26.39760 1.000 15.17386 ? 145 PRO A HB2  1 
ATOM   1873 H  HB3  . PRO A 1 122 ? 0.79867   -0.74731  25.27633 1.000 15.17386 ? 145 PRO A HB3  1 
ATOM   1874 H  HG2  . PRO A 1 122 ? 0.66586   1.75660   25.51373 1.000 15.33226 ? 145 PRO A HG2  1 
ATOM   1875 H  HG3  . PRO A 1 122 ? -0.71155  0.97960   25.35746 1.000 15.33226 ? 145 PRO A HG3  1 
ATOM   1876 H  HD2  . PRO A 1 122 ? 0.43324   1.92912   27.76821 1.000 15.19144 ? 145 PRO A HD2  1 
ATOM   1877 H  HD3  . PRO A 1 122 ? -1.08633  2.06158   27.32238 1.000 15.19144 ? 145 PRO A HD3  1 
ATOM   1878 N  N    . ALA A 1 123 ? 1.55534   -1.35749  29.00337 1.000 12.71407 ? 146 ALA A N    1 
ATOM   1879 C  CA   . ALA A 1 123 ? 2.40140   -2.19727  29.84239 1.000 13.13551 ? 146 ALA A CA   1 
ATOM   1880 C  C    . ALA A 1 123 ? 1.56951   -3.10031  30.74073 1.000 12.45414 ? 146 ALA A C    1 
ATOM   1881 O  O    . ALA A 1 123 ? 2.04117   -4.16206  31.15229 1.000 12.98261 ? 146 ALA A O    1 
ATOM   1882 C  CB   . ALA A 1 123 ? 3.35955   -1.34836  30.68746 1.000 14.18085 ? 146 ALA A CB   1 
ATOM   1883 H  H    . ALA A 1 123 ? 1.59065   -0.51980  29.19478 1.000 15.25689 ? 146 ALA A H    1 
ATOM   1884 H  HA   . ALA A 1 123 ? 2.94506   -2.75291  29.26223 1.000 15.76262 ? 146 ALA A HA   1 
ATOM   1885 H  HB1  . ALA A 1 123 ? 3.86953   -1.93298  31.26973 1.000 17.01702 ? 146 ALA A HB1  1 
ATOM   1886 H  HB2  . ALA A 1 123 ? 3.95846   -0.86556  30.09661 1.000 17.01702 ? 146 ALA A HB2  1 
ATOM   1887 H  HB3  . ALA A 1 123 ? 2.84245   -0.72222  31.21798 1.000 17.01702 ? 146 ALA A HB3  1 
ATOM   1888 N  N    . SER A 1 124 ? 0.33281   -2.69538  31.05091 1.000 12.55589 ? 147 SER A N    1 
ATOM   1889 C  CA   A SER A 1 124 ? -0.53231  -3.56622  31.83786 0.552 13.31367 ? 147 SER A CA   1 
ATOM   1890 C  CA   B SER A 1 124 ? -0.55404  -3.54802  31.83087 0.448 13.60854 ? 147 SER A CA   1 
ATOM   1891 C  C    . SER A 1 124 ? -1.10382  -4.69712  30.99264 1.000 12.30882 ? 147 SER A C    1 
ATOM   1892 O  O    . SER A 1 124 ? -1.28402  -5.80644  31.49888 1.000 12.54003 ? 147 SER A O    1 
ATOM   1893 C  CB   A SER A 1 124 ? -1.67180  -2.79054  32.50640 0.552 14.02346 ? 147 SER A CB   1 
ATOM   1894 C  CB   B SER A 1 124 ? -1.67413  -2.68607  32.40315 0.448 14.72951 ? 147 SER A CB   1 
ATOM   1895 O  OG   A SER A 1 124 ? -2.49053  -3.65675  33.31041 0.552 15.62783 ? 147 SER A OG   1 
ATOM   1896 O  OG   B SER A 1 124 ? -1.13096  -1.48932  32.94009 0.448 16.42970 ? 147 SER A OG   1 
ATOM   1897 H  H    A SER A 1 124 ? -0.01513  -1.94273  30.82274 0.552 15.06707 ? 147 SER A H    1 
ATOM   1898 H  H    B SER A 1 124 ? -0.00882  -1.93987  30.82265 0.448 15.06707 ? 147 SER A H    1 
ATOM   1899 H  HA   A SER A 1 124 ? 0.00225   -3.94340  32.55402 0.552 15.97641 ? 147 SER A HA   1 
ATOM   1900 H  HA   B SER A 1 124 ? -0.06664  -3.94916  32.56737 0.448 16.33025 ? 147 SER A HA   1 
ATOM   1901 H  HB2  A SER A 1 124 ? -1.29214  -2.10143  33.07375 0.552 16.82815 ? 147 SER A HB2  1 
ATOM   1902 H  HB2  B SER A 1 124 ? -2.30066  -2.46457  31.69654 0.448 17.67542 ? 147 SER A HB2  1 
ATOM   1903 H  HB3  A SER A 1 124 ? -2.22325  -2.38695  31.81799 0.552 16.82815 ? 147 SER A HB3  1 
ATOM   1904 H  HB3  B SER A 1 124 ? -2.12749  -3.17598  33.10697 0.448 17.67542 ? 147 SER A HB3  1 
ATOM   1905 H  HG   A SER A 1 124 ? -3.12891  -3.22276  33.64165 0.552 18.75340 ? 147 SER A HG   1 
ATOM   1906 H  HG   B SER A 1 124 ? -1.30343  -1.43835  33.76061 0.448 19.71565 ? 147 SER A HG   1 
ATOM   1907 N  N    . VAL A 1 125 ? -1.35981  -4.46135  29.69622 1.000 10.96197 ? 148 VAL A N    1 
ATOM   1908 C  CA   . VAL A 1 125 ? -1.72862  -5.57427  28.82644 1.000 10.57272 ? 148 VAL A CA   1 
ATOM   1909 C  C    . VAL A 1 125 ? -0.55692  -6.54828  28.72741 1.000 9.85373  ? 148 VAL A C    1 
ATOM   1910 O  O    . VAL A 1 125 ? -0.73425  -7.76111  28.77053 1.000 10.21890 ? 148 VAL A O    1 
ATOM   1911 C  CB   . VAL A 1 125 ? -2.17689  -5.06124  27.44130 1.000 10.78038 ? 148 VAL A CB   1 
ATOM   1912 C  CG1  . VAL A 1 125 ? -2.60571  -6.24749  26.56907 1.000 11.12908 ? 148 VAL A CG1  1 
ATOM   1913 C  CG2  . VAL A 1 125 ? -3.31438  -4.06074  27.55739 1.000 11.37648 ? 148 VAL A CG2  1 
ATOM   1914 H  H    . VAL A 1 125 ? -1.32668  -3.69157  29.31419 1.000 13.15436 ? 148 VAL A H    1 
ATOM   1915 H  HA   . VAL A 1 125 ? -2.48566  -6.04213  29.21232 1.000 12.68727 ? 148 VAL A HA   1 
ATOM   1916 H  HB   . VAL A 1 125 ? -1.42972  -4.60472  27.02389 1.000 12.93646 ? 148 VAL A HB   1 
ATOM   1917 H  HG11 . VAL A 1 125 ? -2.98776  -5.91066  25.74355 1.000 13.35490 ? 148 VAL A HG11 1 
ATOM   1918 H  HG12 . VAL A 1 125 ? -1.82822  -6.79404  26.37490 1.000 13.35490 ? 148 VAL A HG12 1 
ATOM   1919 H  HG13 . VAL A 1 125 ? -3.26604  -6.77060  27.04990 1.000 13.35490 ? 148 VAL A HG13 1 
ATOM   1920 H  HG21 . VAL A 1 125 ? -3.60429  -3.80746  26.66705 1.000 13.65177 ? 148 VAL A HG21 1 
ATOM   1921 H  HG22 . VAL A 1 125 ? -4.04859  -4.47190  28.03987 1.000 13.65177 ? 148 VAL A HG22 1 
ATOM   1922 H  HG23 . VAL A 1 125 ? -2.99956  -3.27898  28.03765 1.000 13.65177 ? 148 VAL A HG23 1 
ATOM   1923 N  N    . THR A 1 126 ? 0.66832   -6.01699  28.61193 1.000 9.97132  ? 149 THR A N    1 
ATOM   1924 C  CA   . THR A 1 126 ? 1.85425   -6.87552  28.59399 1.000 9.09635  ? 149 THR A CA   1 
ATOM   1925 C  C    . THR A 1 126 ? 1.97801   -7.67280  29.88469 1.000 9.36651  ? 149 THR A C    1 
ATOM   1926 O  O    . THR A 1 126 ? 2.30473   -8.86068  29.83686 1.000 10.06950 ? 149 THR A O    1 
ATOM   1927 C  CB   . THR A 1 126 ? 3.11219   -6.02553  28.36666 1.000 9.61376  ? 149 THR A CB   1 
ATOM   1928 O  OG1  . THR A 1 126 ? 2.95514   -5.28827  27.14338 1.000 10.43741 ? 149 THR A OG1  1 
ATOM   1929 C  CG2  . THR A 1 126 ? 4.36391   -6.87982  28.27347 1.000 10.79477 ? 149 THR A CG2  1 
ATOM   1930 H  H    . THR A 1 126 ? 0.83539   -5.17614  28.54366 1.000 11.96558 ? 149 THR A H    1 
ATOM   1931 H  HA   . THR A 1 126 ? 1.77485   -7.50341  27.85890 1.000 10.91561 ? 149 THR A HA   1 
ATOM   1932 H  HB   . THR A 1 126 ? 3.22804   -5.42346  29.11832 1.000 11.53651 ? 149 THR A HB   1 
ATOM   1933 H  HG1  . THR A 1 126 ? 2.28892   -4.77958  27.19803 1.000 12.52490 ? 149 THR A HG1  1 
ATOM   1934 H  HG21 . THR A 1 126 ? 5.13867   -6.31729  28.11787 1.000 12.95372 ? 149 THR A HG21 1 
ATOM   1935 H  HG22 . THR A 1 126 ? 4.49251   -7.37118  29.09986 1.000 12.95372 ? 149 THR A HG22 1 
ATOM   1936 H  HG23 . THR A 1 126 ? 4.28108   -7.51099  27.54157 1.000 12.95372 ? 149 THR A HG23 1 
ATOM   1937 N  N    . ALA A 1 127 ? 1.73344   -7.03293  31.03609 1.000 10.52730 ? 150 ALA A N    1 
ATOM   1938 C  CA   . ALA A 1 127 ? 1.80774   -7.74356  32.30565 1.000 11.81345 ? 150 ALA A CA   1 
ATOM   1939 C  C    . ALA A 1 127 ? 0.78802   -8.88032  32.36512 1.000 11.68177 ? 150 ALA A C    1 
ATOM   1940 O  O    . ALA A 1 127 ? 1.06986   -9.94558  32.93054 1.000 12.35384 ? 150 ALA A O    1 
ATOM   1941 C  CB   . ALA A 1 127 ? 1.57805   -6.77784  33.46927 1.000 13.16863 ? 150 ALA A CB   1 
ATOM   1942 H  H    . ALA A 1 127 ? 1.52619   -6.20096  31.10291 1.000 12.63276 ? 150 ALA A H    1 
ATOM   1943 H  HA   . ALA A 1 127 ? 2.69702   -8.12108  32.39265 1.000 14.17614 ? 150 ALA A HA   1 
ATOM   1944 H  HB1  . ALA A 1 127 ? 1.67782   -7.26056  34.30469 1.000 15.80236 ? 150 ALA A HB1  1 
ATOM   1945 H  HB2  . ALA A 1 127 ? 2.23187   -6.06300  33.42017 1.000 15.80236 ? 150 ALA A HB2  1 
ATOM   1946 H  HB3  . ALA A 1 127 ? 0.68217   -6.41178  33.40372 1.000 15.80236 ? 150 ALA A HB3  1 
ATOM   1947 N  N    . PHE A 1 128 ? -0.40431  -8.66646  31.80094 1.000 10.99436 ? 151 PHE A N    1 
ATOM   1948 C  CA   . PHE A 1 128 ? -1.39899  -9.72857  31.70737 1.000 11.30545 ? 151 PHE A CA   1 
ATOM   1949 C  C    . PHE A 1 128 ? -0.84694  -10.89658 30.90757 1.000 10.20596 ? 151 PHE A C    1 
ATOM   1950 O  O    . PHE A 1 128 ? -0.95740  -12.06083 31.31328 1.000 11.40503 ? 151 PHE A O    1 
ATOM   1951 C  CB   . PHE A 1 128 ? -2.68724  -9.16565  31.09631 1.000 12.47223 ? 151 PHE A CB   1 
ATOM   1952 C  CG   . PHE A 1 128 ? -3.63517  -10.20826 30.59874 1.000 12.53608 ? 151 PHE A CG   1 
ATOM   1953 C  CD1  . PHE A 1 128 ? -4.32316  -11.03883 31.45774 1.000 14.01054 ? 151 PHE A CD1  1 
ATOM   1954 C  CD2  . PHE A 1 128 ? -3.82706  -10.37520 29.23372 1.000 13.29471 ? 151 PHE A CD2  1 
ATOM   1955 C  CE1  . PHE A 1 128 ? -5.20596  -12.01509 30.95382 1.000 14.88014 ? 151 PHE A CE1  1 
ATOM   1956 C  CE2  . PHE A 1 128 ? -4.68283  -11.34302 28.74831 1.000 15.26317 ? 151 PHE A CE2  1 
ATOM   1957 C  CZ   . PHE A 1 128 ? -5.37254  -12.14670 29.60010 1.000 15.19588 ? 151 PHE A CZ   1 
ATOM   1958 H  H    . PHE A 1 128 ? -0.65872  -7.91617  31.46636 1.000 13.19323 ? 151 PHE A H    1 
ATOM   1959 H  HA   . PHE A 1 128 ? -1.62208  -10.06148 32.59072 1.000 13.56654 ? 151 PHE A HA   1 
ATOM   1960 H  HB2  . PHE A 1 128 ? -3.14983  -8.64584  31.77212 1.000 14.96668 ? 151 PHE A HB2  1 
ATOM   1961 H  HB3  . PHE A 1 128 ? -2.45237  -8.59889  30.34497 1.000 14.96668 ? 151 PHE A HB3  1 
ATOM   1962 H  HD1  . PHE A 1 128 ? -4.20384  -10.95426 32.37617 1.000 16.81264 ? 151 PHE A HD1  1 
ATOM   1963 H  HD2  . PHE A 1 128 ? -3.37167  -9.82608  28.63707 1.000 15.95365 ? 151 PHE A HD2  1 
ATOM   1964 H  HE1  . PHE A 1 128 ? -5.67351  -12.56772 31.53768 1.000 17.85616 ? 151 PHE A HE1  1 
ATOM   1965 H  HE2  . PHE A 1 128 ? -4.78850  -11.44619 27.83011 1.000 18.31580 ? 151 PHE A HE2  1 
ATOM   1966 H  HZ   . PHE A 1 128 ? -5.95794  -12.78639 29.26396 1.000 18.23505 ? 151 PHE A HZ   1 
ATOM   1967 N  N    . ALA A 1 129 ? -0.22168  -10.60281 29.76210 1.000 9.89973  ? 152 ALA A N    1 
ATOM   1968 C  CA   . ALA A 1 129 ? 0.39330   -11.65539 28.95658 1.000 9.83597  ? 152 ALA A CA   1 
ATOM   1969 C  C    . ALA A 1 129 ? 1.41933   -12.42068 29.77626 1.000 9.87912  ? 152 ALA A C    1 
ATOM   1970 O  O    . ALA A 1 129 ? 1.45589   -13.64975 29.75351 1.000 11.06445 ? 152 ALA A O    1 
ATOM   1971 C  CB   . ALA A 1 129 ? 1.01795   -11.06218 27.68390 1.000 10.55092 ? 152 ALA A CB   1 
ATOM   1972 H  H    . ALA A 1 129 ? -0.14173  -9.81140  29.43518 1.000 11.87967 ? 152 ALA A H    1 
ATOM   1973 H  HA   . ALA A 1 129 ? -0.29132  -12.28045 28.67109 1.000 11.80317 ? 152 ALA A HA   1 
ATOM   1974 H  HB1  . ALA A 1 129 ? 1.38818   -11.78164 27.14892 1.000 12.66110 ? 152 ALA A HB1  1 
ATOM   1975 H  HB2  . ALA A 1 129 ? 0.33055   -10.59681 27.18209 1.000 12.66110 ? 152 ALA A HB2  1 
ATOM   1976 H  HB3  . ALA A 1 129 ? 1.72019   -10.44239 27.93612 1.000 12.66110 ? 152 ALA A HB3  1 
ATOM   1977 N  N    . ARG A 1 130 ? 2.26825   -11.69355 30.51403 1.000 11.99518 ? 153 ARG A N    1 
ATOM   1978 C  CA   . ARG A 1 130 ? 3.30759   -12.34460 31.29882 1.000 14.09101 ? 153 ARG A CA   1 
ATOM   1979 C  C    . ARG A 1 130 ? 2.69822   -13.25560 32.34364 1.000 14.20491 ? 153 ARG A C    1 
ATOM   1980 O  O    . ARG A 1 130 ? 3.19655   -14.36065 32.59185 1.000 16.05589 ? 153 ARG A O    1 
ATOM   1981 C  CB   . ARG A 1 130 ? 4.19203   -11.30718 31.98634 1.000 14.44864 ? 153 ARG A CB   1 
ATOM   1982 C  CG   . ARG A 1 130 ? 5.00648   -10.44544 31.05197 1.000 14.95985 ? 153 ARG A CG   1 
ATOM   1983 C  CD   . ARG A 1 130 ? 6.12138   -11.22515 30.37684 1.000 15.05733 ? 153 ARG A CD   1 
ATOM   1984 N  NE   . ARG A 1 130 ? 6.81599   -10.35856 29.43127 1.000 14.72961 ? 153 ARG A NE   1 
ATOM   1985 C  CZ   . ARG A 1 130 ? 6.35789   -10.06737 28.22015 1.000 12.71243 ? 153 ARG A CZ   1 
ATOM   1986 N  NH1  . ARG A 1 130 ? 5.29576   -10.67430 27.71475 1.000 11.58375 ? 153 ARG A NH1  1 
ATOM   1987 N  NH2  . ARG A 1 130 ? 6.96989   -9.13272  27.50787 1.000 14.13922 ? 153 ARG A NH2  1 
ATOM   1988 H  H    . ARG A 1 130 ? 2.25942   -10.83561 30.57288 1.000 14.39422 ? 153 ARG A H    1 
ATOM   1989 H  HA   . ARG A 1 130 ? 3.86124   -12.86754 30.69807 1.000 16.90921 ? 153 ARG A HA   1 
ATOM   1990 H  HB2  . ARG A 1 130 ? 3.62517   -10.71683 32.50697 1.000 17.33837 ? 153 ARG A HB2  1 
ATOM   1991 H  HB3  . ARG A 1 130 ? 4.81271   -11.77096 32.56991 1.000 17.33837 ? 153 ARG A HB3  1 
ATOM   1992 H  HG2  . ARG A 1 130 ? 4.42666   -10.08842 30.36114 1.000 17.95182 ? 153 ARG A HG2  1 
ATOM   1993 H  HG3  . ARG A 1 130 ? 5.40768   -9.72017  31.55588 1.000 17.95182 ? 153 ARG A HG3  1 
ATOM   1994 H  HD2  . ARG A 1 130 ? 6.75540   -11.53539 31.04217 1.000 18.06880 ? 153 ARG A HD2  1 
ATOM   1995 H  HD3  . ARG A 1 130 ? 5.74952   -11.98059 29.89525 1.000 18.06880 ? 153 ARG A HD3  1 
ATOM   1996 H  HE   . ARG A 1 130 ? 7.56690   -10.01599 29.67287 1.000 17.67553 ? 153 ARG A HE   1 
ATOM   1997 H  HH11 . ARG A 1 130 ? 4.88423   -11.27400 28.17366 1.000 13.90050 ? 153 ARG A HH11 1 
ATOM   1998 H  HH12 . ARG A 1 130 ? 5.01718   -10.46895 26.92747 1.000 13.90050 ? 153 ARG A HH12 1 
ATOM   1999 H  HH21 . ARG A 1 130 ? 7.65390   -8.72425  27.83172 1.000 16.96706 ? 153 ARG A HH21 1 
ATOM   2000 H  HH22 . ARG A 1 130 ? 6.68312   -8.93452  26.72169 1.000 16.96706 ? 153 ARG A HH22 1 
ATOM   2001 N  N    . GLN A 1 131 ? 1.61674   -12.80057 32.97068 1.000 15.37852 ? 154 GLN A N    1 
ATOM   2002 C  CA   . GLN A 1 131 ? 0.97962   -13.57704 34.02809 1.000 18.35474 ? 154 GLN A CA   1 
ATOM   2003 C  C    . GLN A 1 131 ? 0.39038   -14.86486 33.47405 1.000 18.28858 ? 154 GLN A C    1 
ATOM   2004 O  O    . GLN A 1 131 ? 0.30820   -15.86659 34.20613 1.000 20.21011 ? 154 GLN A O    1 
ATOM   2005 C  CB   . GLN A 1 131 ? -0.03479  -12.67070 34.73044 1.000 21.17871 ? 154 GLN A CB   1 
ATOM   2006 C  CG   . GLN A 1 131 ? -0.60489  -13.13131 36.02929 1.000 23.18707 ? 154 GLN A CG   1 
ATOM   2007 C  CD   . GLN A 1 131 ? 0.42181   -13.54718 37.07910 1.000 22.44059 ? 154 GLN A CD   1 
ATOM   2008 O  OE1  . GLN A 1 131 ? 1.62912   -13.23868 36.98932 1.000 21.36527 ? 154 GLN A OE1  1 
ATOM   2009 N  NE2  . GLN A 1 131 ? -0.05139  -14.26954 38.07345 1.000 22.30126 ? 154 GLN A NE2  1 
ATOM   2010 H  H    . GLN A 1 131 ? 1.23361   -12.04890 32.80390 1.000 18.45422 ? 154 GLN A H    1 
ATOM   2011 H  HA   . GLN A 1 131 ? 1.61117   -13.86160 34.70711 1.000 22.02569 ? 154 GLN A HA   1 
ATOM   2012 H  HB2  . GLN A 1 131 ? 0.39924   -11.82068 34.90358 1.000 25.41445 ? 154 GLN A HB2  1 
ATOM   2013 H  HB3  . GLN A 1 131 ? -0.78413  -12.54390 34.12769 1.000 25.41445 ? 154 GLN A HB3  1 
ATOM   2014 H  HG2  . GLN A 1 131 ? -1.12907  -12.40816 36.40768 1.000 27.82449 ? 154 GLN A HG2  1 
ATOM   2015 H  HG3  . GLN A 1 131 ? -1.17275  -13.89922 35.85974 1.000 27.82449 ? 154 GLN A HG3  1 
ATOM   2016 H  HE21 . GLN A 1 131 ? 0.47463   -14.53688 38.69909 1.000 26.76151 ? 154 GLN A HE21 1 
ATOM   2017 H  HE22 . GLN A 1 131 ? -0.88642  -14.47390 38.09713 1.000 26.76151 ? 154 GLN A HE22 1 
ATOM   2018 N  N    . LEU A 1 132 ? 0.04066   -14.87650 32.18057 1.000 18.00379 ? 155 LEU A N    1 
ATOM   2019 C  CA   . LEU A 1 132 ? -0.39847  -16.08858 31.51909 1.000 17.56623 ? 155 LEU A CA   1 
ATOM   2020 C  C    . LEU A 1 132 ? 0.73838   -17.03988 31.17151 1.000 17.92654 ? 155 LEU A C    1 
ATOM   2021 O  O    . LEU A 1 132 ? 0.46490   -18.20047 30.87547 1.000 20.72271 ? 155 LEU A O    1 
ATOM   2022 C  CB   . LEU A 1 132 ? -1.09812  -15.77970 30.19872 1.000 18.24450 ? 155 LEU A CB   1 
ATOM   2023 C  CG   . LEU A 1 132 ? -2.36737  -14.94485 30.24508 1.000 17.85678 ? 155 LEU A CG   1 
ATOM   2024 C  CD1  . LEU A 1 132 ? -2.94579  -14.85543 28.84328 1.000 18.07640 ? 155 LEU A CD1  1 
ATOM   2025 C  CD2  . LEU A 1 132 ? -3.35931  -15.55455 31.22538 1.000 18.01242 ? 155 LEU A CD2  1 
ATOM   2026 H  H    . LEU A 1 132 ? 0.05244   -14.18538 31.66889 1.000 21.60454 ? 155 LEU A H    1 
ATOM   2027 H  HA   . LEU A 1 132 ? -1.01735  -16.51515 32.13221 1.000 21.07948 ? 155 LEU A HA   1 
ATOM   2028 H  HB2  . LEU A 1 132 ? -0.46929  -15.30046 29.63676 1.000 21.89341 ? 155 LEU A HB2  1 
ATOM   2029 H  HB3  . LEU A 1 132 ? -1.33494  -16.62480 29.78565 1.000 21.89341 ? 155 LEU A HB3  1 
ATOM   2030 H  HG   . LEU A 1 132 ? -2.17791  -14.04561 30.55554 1.000 21.42814 ? 155 LEU A HG   1 
ATOM   2031 H  HD11 . LEU A 1 132 ? -3.70118  -14.24697 28.85156 1.000 21.69168 ? 155 LEU A HD11 1 
ATOM   2032 H  HD12 . LEU A 1 132 ? -2.26179  -14.52536 28.23987 1.000 21.69168 ? 155 LEU A HD12 1 
ATOM   2033 H  HD13 . LEU A 1 132 ? -3.23514  -15.73818 28.56414 1.000 21.69168 ? 155 LEU A HD13 1 
ATOM   2034 H  HD21 . LEU A 1 132 ? -4.21428  -15.10658 31.12920 1.000 21.61491 ? 155 LEU A HD21 1 
ATOM   2035 H  HD22 . LEU A 1 132 ? -3.45704  -16.49945 31.02913 1.000 21.61491 ? 155 LEU A HD22 1 
ATOM   2036 H  HD23 . LEU A 1 132 ? -3.02404  -15.43712 32.12799 1.000 21.61491 ? 155 LEU A HD23 1 
ATOM   2037 N  N    . GLY A 1 133 ? 1.98187   -16.57408 31.16093 1.000 16.28589 ? 156 GLY A N    1 
ATOM   2038 C  CA   . GLY A 1 133 ? 3.10679   -17.36428 30.70478 1.000 15.76404 ? 156 GLY A CA   1 
ATOM   2039 C  C    . GLY A 1 133 ? 3.61853   -17.01618 29.32008 1.000 14.83445 ? 156 GLY A C    1 
ATOM   2040 O  O    . GLY A 1 133 ? 4.45526   -17.75028 28.78024 1.000 17.52869 ? 156 GLY A O    1 
ATOM   2041 H  H    . GLY A 1 133 ? 2.20041   -15.78376 31.42021 1.000 19.54307 ? 156 GLY A H    1 
ATOM   2042 H  HA2  . GLY A 1 133 ? 3.84047   -17.24703 31.32838 1.000 18.91685 ? 156 GLY A HA2  1 
ATOM   2043 H  HA3  . GLY A 1 133 ? 2.84566   -18.29843 30.69643 1.000 18.91685 ? 156 GLY A HA3  1 
ATOM   2044 N  N    . ASP A 1 134 ? 3.14944   -15.92615 28.73439 1.000 11.89689 ? 157 ASP A N    1 
ATOM   2045 C  CA   . ASP A 1 134 ? 3.62682   -15.43510 27.44200 1.000 10.97346 ? 157 ASP A CA   1 
ATOM   2046 C  C    . ASP A 1 134 ? 4.66484   -14.36079 27.73408 1.000 10.46272 ? 157 ASP A C    1 
ATOM   2047 O  O    . ASP A 1 134 ? 4.32891   -13.27548 28.21618 1.000 11.25669 ? 157 ASP A O    1 
ATOM   2048 C  CB   . ASP A 1 134 ? 2.45281   -14.90406 26.62551 1.000 10.46112 ? 157 ASP A CB   1 
ATOM   2049 C  CG   . ASP A 1 134 ? 2.83957   -14.43577 25.24221 1.000 10.44663 ? 157 ASP A CG   1 
ATOM   2050 O  OD1  . ASP A 1 134 ? 4.00084   -14.02120 25.02855 1.000 10.16214 ? 157 ASP A OD1  1 
ATOM   2051 O  OD2  . ASP A 1 134 ? 1.93404   -14.46065 24.38091 1.000 10.57954 ? 157 ASP A OD2  1 
ATOM   2052 H  H    . ASP A 1 134 ? 2.53223   -15.43319 29.07446 1.000 14.27627 ? 157 ASP A H    1 
ATOM   2053 H  HA   . ASP A 1 134 ? 4.05059   -16.13844 26.92563 1.000 13.16815 ? 157 ASP A HA   1 
ATOM   2054 H  HB2  . ASP A 1 134 ? 1.79597   -15.61086 26.52605 1.000 12.55334 ? 157 ASP A HB2  1 
ATOM   2055 H  HB3  . ASP A 1 134 ? 2.06110   -14.15072 27.09448 1.000 12.55334 ? 157 ASP A HB3  1 
ATOM   2056 N  N    . GLU A 1 135 ? 5.92567   -14.68903 27.48417 1.000 10.66853 ? 158 GLU A N    1 
ATOM   2057 C  CA   . GLU A 1 135 ? 7.04489   -13.79638 27.75097 1.000 12.15839 ? 158 GLU A CA   1 
ATOM   2058 C  C    . GLU A 1 135 ? 7.56748   -13.15685 26.47353 1.000 11.92064 ? 158 GLU A C    1 
ATOM   2059 O  O    . GLU A 1 135 ? 8.62691   -12.53875 26.49607 1.000 15.49054 ? 158 GLU A O    1 
ATOM   2060 C  CB   . GLU A 1 135 ? 8.10767   -14.54204 28.59216 1.000 15.21404 ? 158 GLU A CB   1 
ATOM   2061 C  CG   . GLU A 1 135 ? 7.51038   -14.93791 29.98251 1.000 16.33258 ? 158 GLU A CG   1 
ATOM   2062 C  CD   . GLU A 1 135 ? 8.49407   -15.49848 31.00671 1.000 17.17815 ? 158 GLU A CD   1 
ATOM   2063 O  OE1  . GLU A 1 135 ? 9.67744   -15.69327 30.68936 1.000 19.43437 ? 158 GLU A OE1  1 
ATOM   2064 O  OE2  . GLU A 1 135 ? 8.05736   -15.75136 32.16313 1.000 19.45988 ? 158 GLU A OE2  1 
ATOM   2065 H  H    . GLU A 1 135 ? 6.16483   -15.44475 27.15058 1.000 12.80223 ? 158 GLU A H    1 
ATOM   2066 H  HA   . GLU A 1 135 ? 6.78110   -13.04774 28.30851 1.000 14.59007 ? 158 GLU A HA   1 
ATOM   2067 H  HB2  . GLU A 1 135 ? 8.38201   -15.34925 28.12951 1.000 18.25684 ? 158 GLU A HB2  1 
ATOM   2068 H  HB3  . GLU A 1 135 ? 8.87403   -13.96483 28.73507 1.000 18.25684 ? 158 GLU A HB3  1 
ATOM   2069 H  HG2  . GLU A 1 135 ? 7.10984   -14.14685 30.37580 1.000 19.59910 ? 158 GLU A HG2  1 
ATOM   2070 H  HG3  . GLU A 1 135 ? 6.83225   -15.61630 29.83815 1.000 19.59910 ? 158 GLU A HG3  1 
ATOM   2071 N  N    . THR A 1 136 ? 6.80081   -13.24104 25.38216 1.000 10.48719 ? 159 THR A N    1 
ATOM   2072 C  CA   . THR A 1 136 ? 7.16695   -12.68318 24.08315 1.000 10.42850 ? 159 THR A CA   1 
ATOM   2073 C  C    . THR A 1 136 ? 6.32832   -11.47866 23.69938 1.000 9.16841  ? 159 THR A C    1 
ATOM   2074 O  O    . THR A 1 136 ? 6.87189   -10.46885 23.24471 1.000 10.49620 ? 159 THR A O    1 
ATOM   2075 C  CB   . THR A 1 136 ? 7.00747   -13.77515 23.01885 1.000 11.82354 ? 159 THR A CB   1 
ATOM   2076 O  OG1  . THR A 1 136 ? 7.77550   -14.92335 23.41811 1.000 13.87912 ? 159 THR A OG1  1 
ATOM   2077 C  CG2  . THR A 1 136 ? 7.45930   -13.29467 21.63044 1.000 12.09077 ? 159 THR A CG2  1 
ATOM   2078 H  H    . THR A 1 136 ? 6.03503   -13.63230 25.37213 1.000 12.58463 ? 159 THR A H    1 
ATOM   2079 H  HA   . THR A 1 136 ? 8.09370   -12.39697 24.09445 1.000 12.51420 ? 159 THR A HA   1 
ATOM   2080 H  HB   . THR A 1 136 ? 6.07039   -14.01250 22.93851 1.000 14.18825 ? 159 THR A HB   1 
ATOM   2081 H  HG1  . THR A 1 136 ? 8.58580   -14.71505 23.49315 1.000 16.65494 ? 159 THR A HG1  1 
ATOM   2082 H  HG21 . THR A 1 136 ? 7.32023   -13.99618 20.97512 1.000 14.50893 ? 159 THR A HG21 1 
ATOM   2083 H  HG22 . THR A 1 136 ? 6.94897   -12.51274 21.36766 1.000 14.50893 ? 159 THR A HG22 1 
ATOM   2084 H  HG23 . THR A 1 136 ? 8.40128   -13.06398 21.64953 1.000 14.50893 ? 159 THR A HG23 1 
ATOM   2085 N  N    . PHE A 1 137 ? 5.01725   -11.57175 23.88882 1.000 9.47781  ? 160 PHE A N    1 
ATOM   2086 C  CA   . PHE A 1 137 ? 4.10872   -10.47703 23.59279 1.000 8.79179  ? 160 PHE A CA   1 
ATOM   2087 C  C    . PHE A 1 137 ? 4.58086   -9.18800  24.23657 1.000 9.36278  ? 160 PHE A C    1 
ATOM   2088 O  O    . PHE A 1 137 ? 4.92281   -9.14669  25.41983 1.000 10.04363 ? 160 PHE A O    1 
ATOM   2089 C  CB   . PHE A 1 137 ? 2.74232   -10.84326 24.18474 1.000 9.63833  ? 160 PHE A CB   1 
ATOM   2090 C  CG   . PHE A 1 137 ? 1.68236   -9.78220  24.05387 1.000 8.89101  ? 160 PHE A CG   1 
ATOM   2091 C  CD1  . PHE A 1 137 ? 1.58344   -8.77310  24.98902 1.000 9.80974  ? 160 PHE A CD1  1 
ATOM   2092 C  CD2  . PHE A 1 137 ? 0.77606   -9.79431  23.00697 1.000 9.08900  ? 160 PHE A CD2  1 
ATOM   2093 C  CE1  . PHE A 1 137 ? 0.59850   -7.81697  24.90146 1.000 10.11385 ? 160 PHE A CE1  1 
ATOM   2094 C  CE2  . PHE A 1 137 ? -0.19638  -8.82576  22.91136 1.000 9.55498  ? 160 PHE A CE2  1 
ATOM   2095 C  CZ   . PHE A 1 137 ? -0.29276  -7.84194  23.86417 1.000 10.29738 ? 160 PHE A CZ   1 
ATOM   2096 H  H    . PHE A 1 137 ? 4.62243   -12.27227 24.19376 1.000 11.37337 ? 160 PHE A H    1 
ATOM   2097 H  HA   . PHE A 1 137 ? 4.05298   -10.33604 22.63471 1.000 10.55015 ? 160 PHE A HA   1 
ATOM   2098 H  HB2  . PHE A 1 137 ? 2.41546   -11.63690 23.73286 1.000 11.56599 ? 160 PHE A HB2  1 
ATOM   2099 H  HB3  . PHE A 1 137 ? 2.85676   -11.02363 25.13093 1.000 11.56599 ? 160 PHE A HB3  1 
ATOM   2100 H  HD1  . PHE A 1 137 ? 2.19297   -8.73861  25.69057 1.000 11.77169 ? 160 PHE A HD1  1 
ATOM   2101 H  HD2  . PHE A 1 137 ? 0.82516   -10.46317 22.36269 1.000 10.90680 ? 160 PHE A HD2  1 
ATOM   2102 H  HE1  . PHE A 1 137 ? 0.53840   -7.15209  25.54893 1.000 12.13663 ? 160 PHE A HE1  1 
ATOM   2103 H  HE2  . PHE A 1 137 ? -0.79192  -8.83754  22.19715 1.000 11.46598 ? 160 PHE A HE2  1 
ATOM   2104 H  HZ   . PHE A 1 137 ? -0.95978  -7.19661  23.80468 1.000 12.35686 ? 160 PHE A HZ   1 
ATOM   2105 N  N    . ARG A 1 138 ? 4.51628   -8.09728  23.48652 1.000 9.24371  ? 161 ARG A N    1 
ATOM   2106 C  CA   . ARG A 1 138 ? 4.67196   -6.77468  24.08392 1.000 9.76431  ? 161 ARG A CA   1 
ATOM   2107 C  C    . ARG A 1 138 ? 3.73985   -5.78821  23.39906 1.000 9.13344  ? 161 ARG A C    1 
ATOM   2108 O  O    . ARG A 1 138 ? 3.71008   -5.69230  22.16822 1.000 11.34965 ? 161 ARG A O    1 
ATOM   2109 C  CB   . ARG A 1 138 ? 6.13194   -6.29825  24.05505 1.000 11.85589 ? 161 ARG A CB   1 
ATOM   2110 C  CG   . ARG A 1 138 ? 6.81787   -6.35692  22.72682 1.000 12.06810 ? 161 ARG A CG   1 
ATOM   2111 C  CD   . ARG A 1 138 ? 8.27077   -5.91870  22.81078 1.000 11.22527 ? 161 ARG A CD   1 
ATOM   2112 N  NE   . ARG A 1 138 ? 8.34359   -4.48616  23.05119 1.000 11.57567 ? 161 ARG A NE   1 
ATOM   2113 C  CZ   . ARG A 1 138 ? 9.46735   -3.79603  23.06545 1.000 12.80836 ? 161 ARG A CZ   1 
ATOM   2114 N  NH1  . ARG A 1 138 ? 10.63386  -4.39087  22.94480 1.000 14.00391 ? 161 ARG A NH1  1 
ATOM   2115 N  NH2  . ARG A 1 138 ? 9.41170   -2.47537  23.18295 1.000 14.58516 ? 161 ARG A NH2  1 
ATOM   2116 H  H    . ARG A 1 138 ? 4.38444   -8.09499  22.63669 1.000 11.09245 ? 161 ARG A H    1 
ATOM   2117 H  HA   . ARG A 1 138 ? 4.40679   -6.81296  25.01619 1.000 11.71718 ? 161 ARG A HA   1 
ATOM   2118 H  HB2  . ARG A 1 138 ? 6.15438   -5.37379  24.34791 1.000 14.22707 ? 161 ARG A HB2  1 
ATOM   2119 H  HB3  . ARG A 1 138 ? 6.64310   -6.85218  24.66560 1.000 14.22707 ? 161 ARG A HB3  1 
ATOM   2120 H  HG2  . ARG A 1 138 ? 6.79621   -7.26889  22.39706 1.000 14.48172 ? 161 ARG A HG2  1 
ATOM   2121 H  HG3  . ARG A 1 138 ? 6.36054   -5.76864  22.10580 1.000 14.48172 ? 161 ARG A HG3  1 
ATOM   2122 H  HD2  . ARG A 1 138 ? 8.70979   -6.38016  23.54236 1.000 13.47032 ? 161 ARG A HD2  1 
ATOM   2123 H  HD3  . ARG A 1 138 ? 8.72120   -6.11771  21.97507 1.000 13.47032 ? 161 ARG A HD3  1 
ATOM   2124 H  HE   . ARG A 1 138 ? 7.60844   -4.06296  23.19281 1.000 13.89080 ? 161 ARG A HE   1 
ATOM   2125 H  HH11 . ARG A 1 138 ? 10.67360  -5.24519  22.85453 1.000 16.80469 ? 161 ARG A HH11 1 
ATOM   2126 H  HH12 . ARG A 1 138 ? 11.35702  -3.92557  22.95616 1.000 16.80469 ? 161 ARG A HH12 1 
ATOM   2127 H  HH21 . ARG A 1 138 ? 8.65016   -2.08121  23.24848 1.000 17.50219 ? 161 ARG A HH21 1 
ATOM   2128 H  HH22 . ARG A 1 138 ? 10.13718  -2.01366  23.19356 1.000 17.50219 ? 161 ARG A HH22 1 
ATOM   2129 N  N    . LEU A 1 139 ? 2.93959   -5.09126  24.20875 1.000 9.38323  ? 162 LEU A N    1 
ATOM   2130 C  CA   . LEU A 1 139 ? 2.15104   -3.94741  23.77149 1.000 9.09228  ? 162 LEU A CA   1 
ATOM   2131 C  C    . LEU A 1 139 ? 2.80093   -2.71905  24.37616 1.000 10.09531 ? 162 LEU A C    1 
ATOM   2132 O  O    . LEU A 1 139 ? 3.02320   -2.66426  25.59197 1.000 10.95776 ? 162 LEU A O    1 
ATOM   2133 C  CB   . LEU A 1 139 ? 0.68802   -4.07686  24.17633 1.000 9.25342  ? 162 LEU A CB   1 
ATOM   2134 C  CG   . LEU A 1 139 ? -0.25658  -3.15583  23.40596 1.000 10.57518 ? 162 LEU A CG   1 
ATOM   2135 C  CD1  . LEU A 1 139 ? -0.33826  -3.55074  21.92643 1.000 12.09970 ? 162 LEU A CD1  1 
ATOM   2136 C  CD2  . LEU A 1 139 ? -1.64551  -3.14436  24.02534 1.000 11.31592 ? 162 LEU A CD2  1 
ATOM   2137 H  H    . LEU A 1 139 ? 2.83643   -5.27162  25.04327 1.000 11.25988 ? 162 LEU A H    1 
ATOM   2138 H  HA   . LEU A 1 139 ? 2.15301   -3.87314  22.80434 1.000 10.91074 ? 162 LEU A HA   1 
ATOM   2139 H  HB2  . LEU A 1 139 ? 0.40281   -4.99057  24.01922 1.000 11.10410 ? 162 LEU A HB2  1 
ATOM   2140 H  HB3  . LEU A 1 139 ? 0.60713   -3.86144  25.11864 1.000 11.10410 ? 162 LEU A HB3  1 
ATOM   2141 H  HG   . LEU A 1 139 ? 0.10169   -2.25584  23.45641 1.000 12.69021 ? 162 LEU A HG   1 
ATOM   2142 H  HD11 . LEU A 1 139 ? -1.01197  -3.00555  21.49079 1.000 14.51964 ? 162 LEU A HD11 1 
ATOM   2143 H  HD12 . LEU A 1 139 ? 0.52605   -3.40249  21.51183 1.000 14.51964 ? 162 LEU A HD12 1 
ATOM   2144 H  HD13 . LEU A 1 139 ? -0.57931  -4.48814  21.86262 1.000 14.51964 ? 162 LEU A HD13 1 
ATOM   2145 H  HD21 . LEU A 1 139 ? -2.20825  -2.53088  23.52747 1.000 13.57910 ? 162 LEU A HD21 1 
ATOM   2146 H  HD22 . LEU A 1 139 ? -2.01639  -4.03978  23.98566 1.000 13.57910 ? 162 LEU A HD22 1 
ATOM   2147 H  HD23 . LEU A 1 139 ? -1.57714  -2.85526  24.94873 1.000 13.57910 ? 162 LEU A HD23 1 
ATOM   2148 N  N    A ASP A 1 140 ? 3.05476   -1.71967  23.54052 0.714 9.81595  ? 163 ASP A N    1 
ATOM   2149 N  N    B ASP A 1 140 ? 3.16146   -1.77240  23.51267 0.286 11.10025 ? 163 ASP A N    1 
ATOM   2150 C  CA   A ASP A 1 140 ? 3.88916   -0.59801  23.93288 0.714 9.92772  ? 163 ASP A CA   1 
ATOM   2151 C  CA   B ASP A 1 140 ? 3.94467   -0.59936  23.86768 0.286 11.85573 ? 163 ASP A CA   1 
ATOM   2152 C  C    A ASP A 1 140 ? 3.23973   0.74630   23.66501 0.714 10.12066 ? 163 ASP A C    1 
ATOM   2153 C  C    B ASP A 1 140 ? 3.17227   0.69863   23.72361 0.286 10.99859 ? 163 ASP A C    1 
ATOM   2154 O  O    A ASP A 1 140 ? 3.57386   1.73109   24.32773 0.714 10.30352 ? 163 ASP A O    1 
ATOM   2155 O  O    B ASP A 1 140 ? 3.32838   1.59627   24.55325 0.286 11.73401 ? 163 ASP A O    1 
ATOM   2156 C  CB   A ASP A 1 140 ? 5.22049   -0.66142  23.18169 0.714 10.44824 ? 163 ASP A CB   1 
ATOM   2157 C  CB   B ASP A 1 140 ? 5.18179   -0.49280  22.96350 0.286 13.56233 ? 163 ASP A CB   1 
ATOM   2158 C  CG   A ASP A 1 140 ? 6.03041   -1.86022  23.55789 0.714 9.89744  ? 163 ASP A CG   1 
ATOM   2159 C  CG   B ASP A 1 140 ? 6.15857   -1.63161  23.15297 0.286 14.70921 ? 163 ASP A CG   1 
ATOM   2160 O  OD1  A ASP A 1 140 ? 6.57625   -1.85743  24.67306 0.714 12.50766 ? 163 ASP A OD1  1 
ATOM   2161 O  OD1  B ASP A 1 140 ? 5.78341   -2.78771  22.88414 0.286 14.46669 ? 163 ASP A OD1  1 
ATOM   2162 O  OD2  A ASP A 1 140 ? 6.14886   -2.78763  22.74045 0.714 10.39782 ? 163 ASP A OD2  1 
ATOM   2163 O  OD2  B ASP A 1 140 ? 7.31807   -1.35829  23.54011 0.286 16.08177 ? 163 ASP A OD2  1 
ATOM   2164 H  H    A ASP A 1 140 ? 2.75289   -1.66938  22.73681 0.714 11.77914 ? 163 ASP A H    1 
ATOM   2165 H  H    B ASP A 1 140 ? 2.95321   -1.79133  22.67848 0.286 13.32030 ? 163 ASP A H    1 
ATOM   2166 H  HA   A ASP A 1 140 ? 4.03457   -0.66261  24.88975 0.714 11.91326 ? 163 ASP A HA   1 
ATOM   2167 H  HA   B ASP A 1 140 ? 4.23344   -0.69853  24.78838 0.286 14.22688 ? 163 ASP A HA   1 
ATOM   2168 H  HB2  A ASP A 1 140 ? 5.04550   -0.70290  22.22850 0.714 12.53789 ? 163 ASP A HB2  1 
ATOM   2169 H  HB2  B ASP A 1 140 ? 4.89516   -0.49715  22.03683 0.286 16.27480 ? 163 ASP A HB2  1 
ATOM   2170 H  HB3  A ASP A 1 140 ? 5.74025   0.13079   23.38941 0.714 12.53789 ? 163 ASP A HB3  1 
ATOM   2171 H  HB3  B ASP A 1 140 ? 5.64666   0.33482   23.16310 0.286 16.27480 ? 163 ASP A HB3  1 
ATOM   2172 N  N    . ARG A 1 141 ? 2.32670   0.80616   22.70218 1.000 9.58608  ? 164 ARG A N    1 
ATOM   2173 C  CA   . ARG A 1 141 ? 1.68223   2.04313   22.31059 1.000 9.69205  ? 164 ARG A CA   1 
ATOM   2174 C  C    . ARG A 1 141 ? 0.17254   1.86770   22.27727 1.000 9.66783  ? 164 ARG A C    1 
ATOM   2175 O  O    . ARG A 1 141 ? -0.35164  0.75190   22.32333 1.000 10.27547 ? 164 ARG A O    1 
ATOM   2176 C  CB   . ARG A 1 141 ? 2.21660   2.49805   20.94943 1.000 10.31028 ? 164 ARG A CB   1 
ATOM   2177 C  CG   . ARG A 1 141 ? 3.65401   3.03187   21.03869 1.000 10.23093 ? 164 ARG A CG   1 
ATOM   2178 C  CD   . ARG A 1 141 ? 4.23815   3.32720   19.66207 1.000 10.38253 ? 164 ARG A CD   1 
ATOM   2179 N  NE   . ARG A 1 141 ? 4.41108   2.08417   18.92805 1.000 10.80955 ? 164 ARG A NE   1 
ATOM   2180 C  CZ   . ARG A 1 141 ? 4.69816   1.98932   17.63033 1.000 9.83344  ? 164 ARG A CZ   1 
ATOM   2181 N  NH1  . ARG A 1 141 ? 5.03170   3.05554   16.90231 1.000 10.72874 ? 164 ARG A NH1  1 
ATOM   2182 N  NH2  . ARG A 1 141 ? 4.68345   0.79418   17.05551 1.000 11.09646 ? 164 ARG A NH2  1 
ATOM   2183 H  H    . ARG A 1 141 ? 2.05806   0.12540   22.25052 1.000 11.50330 ? 164 ARG A H    1 
ATOM   2184 H  HA   . ARG A 1 141 ? 1.86491   2.73393   22.96658 1.000 11.63046 ? 164 ARG A HA   1 
ATOM   2185 H  HB2  . ARG A 1 141 ? 2.21081   1.74504   20.33801 1.000 12.37234 ? 164 ARG A HB2  1 
ATOM   2186 H  HB3  . ARG A 1 141 ? 1.65089   3.20774   20.60707 1.000 12.37234 ? 164 ARG A HB3  1 
ATOM   2187 H  HG2  . ARG A 1 141 ? 3.65813   3.85461   21.55248 1.000 12.27712 ? 164 ARG A HG2  1 
ATOM   2188 H  HG3  . ARG A 1 141 ? 4.21514   2.36856   21.47002 1.000 12.27712 ? 164 ARG A HG3  1 
ATOM   2189 H  HD2  . ARG A 1 141 ? 3.63472   3.90221   19.16594 1.000 12.45903 ? 164 ARG A HD2  1 
ATOM   2190 H  HD3  . ARG A 1 141 ? 5.10246   3.75702   19.75760 1.000 12.45903 ? 164 ARG A HD3  1 
ATOM   2191 H  HE   . ARG A 1 141 ? 4.32071   1.35030   19.36723 1.000 12.97146 ? 164 ARG A HE   1 
ATOM   2192 H  HH11 . ARG A 1 141 ? 5.06625   3.83276   17.26883 1.000 12.87448 ? 164 ARG A HH11 1 
ATOM   2193 H  HH12 . ARG A 1 141 ? 5.21227   2.96597   16.06627 1.000 12.87448 ? 164 ARG A HH12 1 
ATOM   2194 H  HH21 . ARG A 1 141 ? 4.49076   0.09620   17.51952 1.000 13.31575 ? 164 ARG A HH21 1 
ATOM   2195 H  HH22 . ARG A 1 141 ? 4.86661   0.71718   16.21878 1.000 13.31575 ? 164 ARG A HH22 1 
ATOM   2196 N  N    . THR A 1 142 ? -0.51564  3.00747   22.21783 1.000 10.03474 ? 165 THR A N    1 
ATOM   2197 C  CA   . THR A 1 142 ? -1.93665  3.07055   21.98693 1.000 10.30183 ? 165 THR A CA   1 
ATOM   2198 C  C    . THR A 1 142 ? -2.23077  3.13670   20.49073 1.000 8.92738  ? 165 THR A C    1 
ATOM   2199 O  O    . THR A 1 142 ? -1.33247  3.17280   19.64766 1.000 9.98582  ? 165 THR A O    1 
ATOM   2200 C  CB   . THR A 1 142 ? -2.50096  4.29123   22.70530 1.000 11.02068 ? 165 THR A CB   1 
ATOM   2201 O  OG1  . THR A 1 142 ? -1.83579  5.45538   22.21165 1.000 12.17958 ? 165 THR A OG1  1 
ATOM   2202 C  CG2  . THR A 1 142 ? -2.33659  4.19073   24.21920 1.000 12.47000 ? 165 THR A CG2  1 
ATOM   2203 H  H    . THR A 1 142 ? -0.15786  3.78366   22.31337 1.000 12.04169 ? 165 THR A H    1 
ATOM   2204 H  HA   . THR A 1 142 ? -2.35484  2.26806   22.33626 1.000 12.36220 ? 165 THR A HA   1 
ATOM   2205 H  HB   . THR A 1 142 ? -3.45420  4.35492   22.53745 1.000 13.22482 ? 165 THR A HB   1 
ATOM   2206 H  HG1  . THR A 1 142 ? -2.08539  5.61751   21.42615 1.000 14.61550 ? 165 THR A HG1  1 
ATOM   2207 H  HG21 . THR A 1 142 ? -2.78414  4.93478   24.65162 1.000 14.96400 ? 165 THR A HG21 1 
ATOM   2208 H  HG22 . THR A 1 142 ? -2.72309  3.36111   24.54053 1.000 14.96400 ? 165 THR A HG22 1 
ATOM   2209 H  HG23 . THR A 1 142 ? -1.39534  4.21076   24.45277 1.000 14.96400 ? 165 THR A HG23 1 
ATOM   2210 N  N    . GLU A 1 143 ? -3.51763  3.15524   20.15293 1.000 9.60775  ? 166 GLU A N    1 
ATOM   2211 C  CA   . GLU A 1 143 ? -3.95723  3.45011   18.79604 1.000 10.39659 ? 166 GLU A CA   1 
ATOM   2212 C  C    . GLU A 1 143 ? -3.87237  4.94986   18.55899 1.000 10.46137 ? 166 GLU A C    1 
ATOM   2213 O  O    . GLU A 1 143 ? -4.24374  5.72595   19.43852 1.000 11.47623 ? 166 GLU A O    1 
ATOM   2214 C  CB   . GLU A 1 143 ? -5.40007  3.00593   18.58303 1.000 10.28471 ? 166 GLU A CB   1 
ATOM   2215 C  CG   . GLU A 1 143 ? -5.63591  1.52239   18.75379 1.000 9.83859  ? 166 GLU A CG   1 
ATOM   2216 C  CD   . GLU A 1 143 ? -5.05185  0.66281   17.64147 1.000 10.31557 ? 166 GLU A CD   1 
ATOM   2217 O  OE1  . GLU A 1 143 ? -4.44595  1.19630   16.68805 1.000 11.24507 ? 166 GLU A OE1  1 
ATOM   2218 O  OE2  . GLU A 1 143 ? -5.23480  -0.57951  17.74935 1.000 10.27907 ? 166 GLU A OE2  1 
ATOM   2219 H  H    . GLU A 1 143 ? -4.16362  2.99834   20.69852 1.000 11.52929 ? 166 GLU A H    1 
ATOM   2220 H  HA   . GLU A 1 143 ? -3.39331  2.98013   18.16199 1.000 12.47590 ? 166 GLU A HA   1 
ATOM   2221 H  HB2  . GLU A 1 143 ? -5.96240  3.46694   19.22502 1.000 12.34165 ? 166 GLU A HB2  1 
ATOM   2222 H  HB3  . GLU A 1 143 ? -5.66505  3.24186   17.68025 1.000 12.34165 ? 166 GLU A HB3  1 
ATOM   2223 H  HG2  . GLU A 1 143 ? -5.23054  1.23794   19.58785 1.000 11.80630 ? 166 GLU A HG2  1 
ATOM   2224 H  HG3  . GLU A 1 143 ? -6.59211  1.36114   18.77770 1.000 11.80630 ? 166 GLU A HG3  1 
ATOM   2225 N  N    . PRO A 1 144 ? -3.45005  5.38804   17.37078 1.000 11.63111 ? 167 PRO A N    1 
ATOM   2226 C  CA   . PRO A 1 144 ? -3.21073  4.59534   16.16995 1.000 12.84429 ? 167 PRO A CA   1 
ATOM   2227 C  C    . PRO A 1 144 ? -1.77091  4.17762   15.95851 1.000 11.53915 ? 167 PRO A C    1 
ATOM   2228 O  O    . PRO A 1 144 ? -1.47503  3.44443   15.01254 1.000 12.13595 ? 167 PRO A O    1 
ATOM   2229 C  CB   . PRO A 1 144 ? -3.62538  5.57287   15.05103 1.000 14.98968 ? 167 PRO A CB   1 
ATOM   2230 C  CG   . PRO A 1 144 ? -3.16767  6.90063   15.58594 1.000 15.50383 ? 167 PRO A CG   1 
ATOM   2231 C  CD   . PRO A 1 144 ? -3.48978  6.83139   17.06887 1.000 12.78636 ? 167 PRO A CD   1 
ATOM   2232 H  HA   . PRO A 1 144 ? -3.77374  3.80647   16.21001 1.000 15.41315 ? 167 PRO A HA   1 
ATOM   2233 H  HB2  . PRO A 1 144 ? -3.17526  5.34946   14.22135 1.000 17.98762 ? 167 PRO A HB2  1 
ATOM   2234 H  HB3  . PRO A 1 144 ? -4.58665  5.55348   14.92262 1.000 17.98762 ? 167 PRO A HB3  1 
ATOM   2235 H  HG2  . PRO A 1 144 ? -2.21509  7.00980   15.43906 1.000 18.60460 ? 167 PRO A HG2  1 
ATOM   2236 H  HG3  . PRO A 1 144 ? -3.65446  7.62046   15.15492 1.000 18.60460 ? 167 PRO A HG3  1 
ATOM   2237 H  HD2  . PRO A 1 144 ? -2.82362  7.30904   17.58751 1.000 15.34363 ? 167 PRO A HD2  1 
ATOM   2238 H  HD3  . PRO A 1 144 ? -4.37144  7.19499   17.24598 1.000 15.34363 ? 167 PRO A HD3  1 
ATOM   2239 N  N    . THR A 1 145 ? -0.84652  4.64125   16.79768 1.000 10.71972 ? 168 THR A N    1 
ATOM   2240 C  CA   . THR A 1 145 ? 0.56004   4.48184   16.47470 1.000 10.47556 ? 168 THR A CA   1 
ATOM   2241 C  C    . THR A 1 145 ? 1.04049   3.04588   16.61534 1.000 10.20806 ? 168 THR A C    1 
ATOM   2242 O  O    . THR A 1 145 ? 2.08717   2.71351   16.06186 1.000 11.00300 ? 168 THR A O    1 
ATOM   2243 C  CB   . THR A 1 145 ? 1.44533   5.41316   17.30681 1.000 11.64176 ? 168 THR A CB   1 
ATOM   2244 O  OG1  . THR A 1 145 ? 1.26586   5.10639   18.69074 1.000 11.97158 ? 168 THR A OG1  1 
ATOM   2245 C  CG2  . THR A 1 145 ? 1.12868   6.88285   17.03672 1.000 14.30726 ? 168 THR A CG2  1 
ATOM   2246 H  H    . THR A 1 145 ? -1.00779  5.04162   17.54152 1.000 12.86366 ? 168 THR A H    1 
ATOM   2247 H  HA   . THR A 1 145 ? 0.66982   4.74553   15.54771 1.000 12.57067 ? 168 THR A HA   1 
ATOM   2248 H  HB   . THR A 1 145 ? 2.37527   5.28284   17.06365 1.000 13.97011 ? 168 THR A HB   1 
ATOM   2249 H  HG1  . THR A 1 145 ? 1.72000   5.63223   19.16281 1.000 14.36590 ? 168 THR A HG1  1 
ATOM   2250 H  HG21 . THR A 1 145 ? 1.72232   7.45040   17.55283 1.000 17.16871 ? 168 THR A HG21 1 
ATOM   2251 H  HG22 . THR A 1 145 ? 1.24566   7.07963   16.09412 1.000 17.16871 ? 168 THR A HG22 1 
ATOM   2252 H  HG23 . THR A 1 145 ? 0.21173   7.07613   17.28723 1.000 17.16871 ? 168 THR A HG23 1 
ATOM   2253 N  N    . LEU A 1 146 ? 0.31536   2.18347   17.33840 1.000 10.25443 ? 169 LEU A N    1 
ATOM   2254 C  CA   . LEU A 1 146 ? 0.78482   0.81129   17.49522 1.000 10.01524 ? 169 LEU A CA   1 
ATOM   2255 C  C    . LEU A 1 146 ? 0.82571   0.04489   16.17694 1.000 10.20838 ? 169 LEU A C    1 
ATOM   2256 O  O    . LEU A 1 146 ? 1.39882   -1.03686  16.13994 1.000 10.56914 ? 169 LEU A O    1 
ATOM   2257 C  CB   . LEU A 1 146 ? 0.00867   0.07353   18.59495 1.000 9.46649  ? 169 LEU A CB   1 
ATOM   2258 C  CG   . LEU A 1 146 ? -1.43650  -0.34749  18.32122 1.000 9.83631  ? 169 LEU A CG   1 
ATOM   2259 C  CD1  . LEU A 1 146 ? -1.52435  -1.65155  17.56762 1.000 12.03602 ? 169 LEU A CD1  1 
ATOM   2260 C  CD2  . LEU A 1 146 ? -2.20338  -0.44655  19.63570 1.000 10.32336 ? 169 LEU A CD2  1 
ATOM   2261 H  H    . LEU A 1 146 ? -0.42640  2.36664   17.73316 1.000 12.30531 ? 169 LEU A H    1 
ATOM   2262 H  HA   . LEU A 1 146 ? 1.69892   0.82915   17.81926 1.000 12.01829 ? 169 LEU A HA   1 
ATOM   2263 H  HB2  . LEU A 1 146 ? 0.49726   -0.73854  18.80163 1.000 11.35978 ? 169 LEU A HB2  1 
ATOM   2264 H  HB3  . LEU A 1 146 ? -0.01621  0.65277   19.37261 1.000 11.35978 ? 169 LEU A HB3  1 
ATOM   2265 H  HG   . LEU A 1 146 ? -1.84444  0.32838   17.75758 1.000 11.80357 ? 169 LEU A HG   1 
ATOM   2266 H  HD11 . LEU A 1 146 ? -2.45562  -1.91374  17.49766 1.000 14.44323 ? 169 LEU A HD11 1 
ATOM   2267 H  HD12 . LEU A 1 146 ? -1.14735  -1.53059  16.68211 1.000 14.44323 ? 169 LEU A HD12 1 
ATOM   2268 H  HD13 . LEU A 1 146 ? -1.02525  -2.32922  18.04987 1.000 14.44323 ? 169 LEU A HD13 1 
ATOM   2269 H  HD21 . LEU A 1 146 ? -3.10533  -0.75302  19.45278 1.000 12.38803 ? 169 LEU A HD21 1 
ATOM   2270 H  HD22 . LEU A 1 146 ? -1.75155  -1.07701  20.21817 1.000 12.38803 ? 169 LEU A HD22 1 
ATOM   2271 H  HD23 . LEU A 1 146 ? -2.22966  0.42883   20.05273 1.000 12.38803 ? 169 LEU A HD23 1 
ATOM   2272 N  N    A ASN A 1 147 ? 0.28833   0.59247   15.08987 0.623 10.24911 ? 170 ASN A N    1 
ATOM   2273 N  N    B ASN A 1 147 ? 0.27370   0.60651   15.09916 0.377 10.36203 ? 170 ASN A N    1 
ATOM   2274 C  CA   A ASN A 1 147 ? 0.29371   -0.09637  13.80310 0.623 11.32603 ? 170 ASN A CA   1 
ATOM   2275 C  CA   B ASN A 1 147 ? 0.22412   -0.04466  13.79481 0.377 10.92549 ? 170 ASN A CA   1 
ATOM   2276 C  C    A ASN A 1 147 ? 1.35590   0.38499   12.83210 0.623 10.83836 ? 170 ASN A C    1 
ATOM   2277 C  C    B ASN A 1 147 ? 1.36815   0.33492   12.85004 0.377 10.90553 ? 170 ASN A C    1 
ATOM   2278 O  O    A ASN A 1 147 ? 1.26194   0.07793   11.64379 0.623 11.93210 ? 170 ASN A O    1 
ATOM   2279 O  O    B ASN A 1 147 ? 1.36488   -0.12413  11.70524 0.377 11.88936 ? 170 ASN A O    1 
ATOM   2280 C  CB   A ASN A 1 147 ? -1.05901  0.06681   13.12317 0.623 12.10535 ? 170 ASN A CB   1 
ATOM   2281 C  CB   B ASN A 1 147 ? -1.11636  0.27464   13.09633 0.377 10.71725 ? 170 ASN A CB   1 
ATOM   2282 C  CG   A ASN A 1 147 ? -2.18156  -0.24320  14.03052 0.623 12.29955 ? 170 ASN A CG   1 
ATOM   2283 C  CG   B ASN A 1 147 ? -2.31072  -0.46944  13.70228 0.377 11.14278 ? 170 ASN A CG   1 
ATOM   2284 O  OD1  A ASN A 1 147 ? -2.50903  -1.40351  14.25073 0.623 10.71796 ? 170 ASN A OD1  1 
ATOM   2285 O  OD1  B ASN A 1 147 ? -2.15009  -1.49635  14.34348 0.377 9.76610  ? 170 ASN A OD1  1 
ATOM   2286 N  ND2  A ASN A 1 147 ? -2.79067  0.78568   14.56900 0.623 11.88102 ? 170 ASN A ND2  1 
ATOM   2287 N  ND2  B ASN A 1 147 ? -3.52206  0.05431   13.47921 0.377 11.30191 ? 170 ASN A ND2  1 
ATOM   2288 H  H    A ASN A 1 147 ? -0.08706  1.36603   15.07307 0.623 12.29893 ? 170 ASN A H    1 
ATOM   2289 H  H    B ASN A 1 147 ? -0.08820  1.38665   15.10158 0.377 12.43444 ? 170 ASN A H    1 
ATOM   2290 H  HA   A ASN A 1 147 ? 0.46732   -1.03139  13.99419 0.623 13.59124 ? 170 ASN A HA   1 
ATOM   2291 H  HA   B ASN A 1 147 ? 0.28540   -1.00004  13.95101 0.377 13.11058 ? 170 ASN A HA   1 
ATOM   2292 H  HB2  A ASN A 1 147 ? -1.15636  0.98462   12.82477 0.623 14.52642 ? 170 ASN A HB2  1 
ATOM   2293 H  HB2  B ASN A 1 147 ? -1.29002  1.22605   13.17090 0.377 12.86070 ? 170 ASN A HB2  1 
ATOM   2294 H  HB3  A ASN A 1 147 ? -1.10846  -0.53570  12.36459 0.623 14.52642 ? 170 ASN A HB3  1 
ATOM   2295 H  HB3  B ASN A 1 147 ? -1.05135  0.02148   12.16221 0.377 12.86070 ? 170 ASN A HB3  1 
ATOM   2296 H  HD21 A ASN A 1 147 ? -3.45142  0.66183   15.10535 0.623 14.25723 ? 170 ASN A HD21 1 
ATOM   2297 H  HD21 B ASN A 1 147 ? -4.22197  -0.32904  13.79978 0.377 13.56230 ? 170 ASN A HD21 1 
ATOM   2298 H  HD22 A ASN A 1 147 ? -2.52938  1.58428   14.38582 0.623 14.25723 ? 170 ASN A HD22 1 
ATOM   2299 H  HD22 B ASN A 1 147 ? -3.60049  0.77420   13.01530 0.377 13.56230 ? 170 ASN A HD22 1 
ATOM   2300 N  N    . THR A 1 148 ? 2.35168   1.13835   13.28102 1.000 10.95342 ? 171 THR A N    1 
ATOM   2301 C  CA   . THR A 1 148 ? 3.33831   1.64337   12.32383 1.000 11.62325 ? 171 THR A CA   1 
ATOM   2302 C  C    . THR A 1 148 ? 4.10213   0.51792   11.62526 1.000 11.19118 ? 171 THR A C    1 
ATOM   2303 O  O    . THR A 1 148 ? 4.44256   0.63462   10.43528 1.000 11.54217 ? 171 THR A O    1 
ATOM   2304 C  CB   . THR A 1 148 ? 4.31006   2.63049   12.97066 1.000 12.25835 ? 171 THR A CB   1 
ATOM   2305 O  OG1  . THR A 1 148 ? 4.84088   2.08397   14.17830 1.000 12.06073 ? 171 THR A OG1  1 
ATOM   2306 C  CG2  . THR A 1 148 ? 3.62789   3.95080   13.28321 1.000 13.55832 ? 171 THR A CG2  1 
ATOM   2307 H  H    . THR A 1 148 ? 2.47530   1.36359   14.10174 1.000 13.14411 ? 171 THR A H    1 
ATOM   2308 H  HA   . THR A 1 148 ? 2.84338   2.13216   11.64780 1.000 13.94790 ? 171 THR A HA   1 
ATOM   2309 H  HB   . THR A 1 148 ? 5.03353   2.80060   12.34731 1.000 14.71002 ? 171 THR A HB   1 
ATOM   2310 H  HG1  . THR A 1 148 ? 5.29419   1.39757   14.00811 1.000 14.47288 ? 171 THR A HG1  1 
ATOM   2311 H  HG21 . THR A 1 148 ? 4.26316   4.56643   13.68112 1.000 16.26999 ? 171 THR A HG21 1 
ATOM   2312 H  HG22 . THR A 1 148 ? 3.27658   4.34366   12.46887 1.000 16.26999 ? 171 THR A HG22 1 
ATOM   2313 H  HG23 . THR A 1 148 ? 2.89685   3.80761   13.90448 1.000 16.26999 ? 171 THR A HG23 1 
ATOM   2314 N  N    . ALA A 1 149 ? 4.43724   -0.54817  12.36282 1.000 11.57163 ? 172 ALA A N    1 
ATOM   2315 C  CA   . ALA A 1 149 ? 5.02381   -1.76141  11.79111 1.000 11.31642 ? 172 ALA A CA   1 
ATOM   2316 C  C    . ALA A 1 149 ? 6.33248   -1.49645  11.04627 1.000 11.95003 ? 172 ALA A C    1 
ATOM   2317 O  O    . ALA A 1 149 ? 6.59360   -2.07368  9.98770  1.000 12.43339 ? 172 ALA A O    1 
ATOM   2318 C  CB   . ALA A 1 149 ? 4.01055   -2.50586  10.91947 1.000 11.93465 ? 172 ALA A CB   1 
ATOM   2319 H  H    . ALA A 1 149 ? 4.33127   -0.59150  13.21516 1.000 13.88595 ? 172 ALA A H    1 
ATOM   2320 H  HA   . ALA A 1 149 ? 5.26354   -2.34453  12.52827 1.000 13.57970 ? 172 ALA A HA   1 
ATOM   2321 H  HB1  . ALA A 1 149 ? 4.42176   -3.31562  10.57875 1.000 14.32158 ? 172 ALA A HB1  1 
ATOM   2322 H  HB2  . ALA A 1 149 ? 3.23526   -2.72979  11.45768 1.000 14.32158 ? 172 ALA A HB2  1 
ATOM   2323 H  HB3  . ALA A 1 149 ? 3.74718   -1.93316  10.18220 1.000 14.32158 ? 172 ALA A HB3  1 
ATOM   2324 N  N    . ILE A 1 150 ? 7.17630   -0.65961  11.63284 1.000 12.55907 ? 173 ILE A N    1 
ATOM   2325 C  CA   . ILE A 1 150 ? 8.44907   -0.30930  10.99409 1.000 13.98686 ? 173 ILE A CA   1 
ATOM   2326 C  C    . ILE A 1 150 ? 9.39599   -1.49768  11.09024 1.000 14.14792 ? 173 ILE A C    1 
ATOM   2327 O  O    . ILE A 1 150 ? 9.55411   -2.07311  12.18004 1.000 13.46415 ? 173 ILE A O    1 
ATOM   2328 C  CB   . ILE A 1 150 ? 9.04962   0.91776   11.68115 1.000 15.28887 ? 173 ILE A CB   1 
ATOM   2329 C  CG1  . ILE A 1 150 ? 8.09078   2.09880   11.54172 1.000 16.37441 ? 173 ILE A CG1  1 
ATOM   2330 C  CG2  . ILE A 1 150 ? 10.43833  1.23079   11.09503 1.000 17.03891 ? 173 ILE A CG2  1 
ATOM   2331 C  CD1  . ILE A 1 150 ? 8.33825   3.20962   12.52953 1.000 17.93748 ? 173 ILE A CD1  1 
ATOM   2332 H  H    . ILE A 1 150 ? 7.04298   -0.28107  12.39345 1.000 15.07089 ? 173 ILE A H    1 
ATOM   2333 H  HA   . ILE A 1 150 ? 8.30131   -0.10678  10.05705 1.000 16.78423 ? 173 ILE A HA   1 
ATOM   2334 H  HB   . ILE A 1 150 ? 9.16905   0.73681   12.62661 1.000 18.34665 ? 173 ILE A HB   1 
ATOM   2335 H  HG12 . ILE A 1 150 ? 8.18302   2.47060   10.65056 1.000 19.64930 ? 173 ILE A HG12 1 
ATOM   2336 H  HG13 . ILE A 1 150 ? 7.18430   1.78088   11.67636 1.000 19.64930 ? 173 ILE A HG13 1 
ATOM   2337 H  HG21 . ILE A 1 150 ? 10.74722  2.07887   11.45035 1.000 20.44669 ? 173 ILE A HG21 1 
ATOM   2338 H  HG22 . ILE A 1 150 ? 11.05338  0.52365   11.34515 1.000 20.44669 ? 173 ILE A HG22 1 
ATOM   2339 H  HG23 . ILE A 1 150 ? 10.36899  1.28249   10.12889 1.000 20.44669 ? 173 ILE A HG23 1 
ATOM   2340 H  HD11 . ILE A 1 150 ? 7.66772   3.89918   12.40386 1.000 21.52497 ? 173 ILE A HD11 1 
ATOM   2341 H  HD12 . ILE A 1 150 ? 8.27964   2.85124   13.42899 1.000 21.52497 ? 173 ILE A HD12 1 
ATOM   2342 H  HD13 . ILE A 1 150 ? 9.22298   3.57679   12.37676 1.000 21.52497 ? 173 ILE A HD13 1 
ATOM   2343 N  N    . PRO A 1 151 ? 10.06527  -1.88236  10.00689 1.000 14.96400 ? 174 PRO A N    1 
ATOM   2344 C  CA   . PRO A 1 151 ? 10.99729  -3.00824  10.08624 1.000 15.70928 ? 174 PRO A CA   1 
ATOM   2345 C  C    . PRO A 1 151 ? 12.06784  -2.74513  11.13243 1.000 16.21455 ? 174 PRO A C    1 
ATOM   2346 O  O    . PRO A 1 151 ? 12.60610  -1.64411  11.23206 1.000 16.40182 ? 174 PRO A O    1 
ATOM   2347 C  CB   . PRO A 1 151 ? 11.58313  -3.08161  8.67186  1.000 18.13257 ? 174 PRO A CB   1 
ATOM   2348 C  CG   . PRO A 1 151 ? 10.51112  -2.47743  7.79451  1.000 19.42637 ? 174 PRO A CG   1 
ATOM   2349 C  CD   . PRO A 1 151 ? 9.92650   -1.36602  8.63503  1.000 16.70759 ? 174 PRO A CD   1 
ATOM   2350 H  HA   . PRO A 1 151 ? 10.53602  -3.83753  10.28726 1.000 18.85114 ? 174 PRO A HA   1 
ATOM   2351 H  HB2  . PRO A 1 151 ? 12.40478  -2.56824  8.62434  1.000 21.75908 ? 174 PRO A HB2  1 
ATOM   2352 H  HB3  . PRO A 1 151 ? 11.75445  -4.00509  8.42950  1.000 21.75908 ? 174 PRO A HB3  1 
ATOM   2353 H  HG2  . PRO A 1 151 ? 10.90426  -2.12913  6.97901  1.000 23.31164 ? 174 PRO A HG2  1 
ATOM   2354 H  HG3  . PRO A 1 151 ? 9.83977   -3.14413  7.58073  1.000 23.31164 ? 174 PRO A HG3  1 
ATOM   2355 H  HD2  . PRO A 1 151 ? 10.42936  -0.54436  8.52143  1.000 20.04911 ? 174 PRO A HD2  1 
ATOM   2356 H  HD3  . PRO A 1 151 ? 8.99393   -1.21760  8.41324  1.000 20.04911 ? 174 PRO A HD3  1 
ATOM   2357 N  N    . GLY A 1 152 ? 12.34570  -3.76311  11.94228 1.000 16.44759 ? 175 GLY A N    1 
ATOM   2358 C  CA   . GLY A 1 152 ? 13.33703  -3.66390  12.98623 1.000 16.96865 ? 175 GLY A CA   1 
ATOM   2359 C  C    . GLY A 1 152 ? 12.82596  -3.12402  14.30961 1.000 16.37415 ? 175 GLY A C    1 
ATOM   2360 O  O    . GLY A 1 152 ? 13.55054  -3.18883  15.31433 1.000 18.12041 ? 175 GLY A O    1 
ATOM   2361 H  H    . GLY A 1 152 ? 11.96217  -4.53167  11.89953 1.000 19.73711 ? 175 GLY A H    1 
ATOM   2362 H  HA2  . GLY A 1 152 ? 13.70387  -4.54682  13.14988 1.000 20.36237 ? 175 GLY A HA2  1 
ATOM   2363 H  HA3  . GLY A 1 152 ? 14.04804  -3.07766  12.68344 1.000 20.36237 ? 175 GLY A HA3  1 
ATOM   2364 N  N    . ASP A 1 153 ? 11.59676  -2.61889  14.35286 1.000 13.69983 ? 176 ASP A N    1 
ATOM   2365 C  CA   . ASP A 1 153 ? 11.04888  -1.99020  15.55567 1.000 13.24268 ? 176 ASP A CA   1 
ATOM   2366 C  C    . ASP A 1 153 ? 10.34166  -3.05122  16.38016 1.000 12.75637 ? 176 ASP A C    1 
ATOM   2367 O  O    . ASP A 1 153 ? 9.39298   -3.67200  15.88469 1.000 12.56556 ? 176 ASP A O    1 
ATOM   2368 C  CB   . ASP A 1 153 ? 10.06828  -0.91090  15.13237 1.000 12.78291 ? 176 ASP A CB   1 
ATOM   2369 C  CG   . ASP A 1 153 ? 9.54499   -0.06041  16.26978 1.000 13.70873 ? 176 ASP A CG   1 
ATOM   2370 O  OD1  . ASP A 1 153 ? 9.74883   -0.38373  17.45942 1.000 13.98613 ? 176 ASP A OD1  1 
ATOM   2371 O  OD2  . ASP A 1 153 ? 8.89783   0.95945   15.94848 1.000 15.69618 ? 176 ASP A OD2  1 
ATOM   2372 H  H    . ASP A 1 153 ? 11.04956  -2.62678  13.68945 1.000 16.43980 ? 176 ASP A H    1 
ATOM   2373 H  HA   . ASP A 1 153 ? 11.74480  -1.59483  16.10364 1.000 15.89122 ? 176 ASP A HA   1 
ATOM   2374 H  HB2  . ASP A 1 153 ? 10.51105  -0.31933  14.50396 1.000 15.33950 ? 176 ASP A HB2  1 
ATOM   2375 H  HB3  . ASP A 1 153 ? 9.30555   -1.33442  14.70837 1.000 15.33950 ? 176 ASP A HB3  1 
ATOM   2376 N  N    . PRO A 1 154 ? 10.76875  -3.31664  17.61389 1.000 13.08960 ? 177 PRO A N    1 
ATOM   2377 C  CA   . PRO A 1 154 ? 10.11005  -4.36654  18.39247 1.000 12.14625 ? 177 PRO A CA   1 
ATOM   2378 C  C    . PRO A 1 154 ? 8.84072   -3.91522  19.08750 1.000 10.24463 ? 177 PRO A C    1 
ATOM   2379 O  O    . PRO A 1 154 ? 8.17786   -4.73761  19.72104 1.000 10.87965 ? 177 PRO A O    1 
ATOM   2380 C  CB   . PRO A 1 154 ? 11.17267  -4.72325  19.42545 1.000 14.04759 ? 177 PRO A CB   1 
ATOM   2381 C  CG   . PRO A 1 154 ? 11.87688  -3.39901  19.69430 1.000 15.82690 ? 177 PRO A CG   1 
ATOM   2382 C  CD   . PRO A 1 154 ? 11.93826  -2.74265  18.31605 1.000 14.66581 ? 177 PRO A CD   1 
ATOM   2383 H  HA   . PRO A 1 154 ? 9.92064   -5.13524  17.83200 1.000 14.57550 ? 177 PRO A HA   1 
ATOM   2384 H  HB2  . PRO A 1 154 ? 10.75521  -5.06905  20.22985 1.000 16.85711 ? 177 PRO A HB2  1 
ATOM   2385 H  HB3  . PRO A 1 154 ? 11.78649  -5.38027  19.06151 1.000 16.85711 ? 177 PRO A HB3  1 
ATOM   2386 H  HG2  . PRO A 1 154 ? 11.36076  -2.86337  20.31688 1.000 18.99227 ? 177 PRO A HG2  1 
ATOM   2387 H  HG3  . PRO A 1 154 ? 12.76571  -3.55622  20.04950 1.000 18.99227 ? 177 PRO A HG3  1 
ATOM   2388 H  HD2  . PRO A 1 154 ? 11.85844  -1.77869  18.38880 1.000 17.59897 ? 177 PRO A HD2  1 
ATOM   2389 H  HD3  . PRO A 1 154 ? 12.76253  -2.97381  17.85991 1.000 17.59897 ? 177 PRO A HD3  1 
ATOM   2390 N  N    . ARG A 1 155 ? 8.48371   -2.64092  19.02178 1.000 11.21904 ? 178 ARG A N    1 
ATOM   2391 C  CA   . ARG A 1 155 ? 7.28304   -2.20088  19.71688 1.000 10.14949 ? 178 ARG A CA   1 
ATOM   2392 C  C    . ARG A 1 155 ? 6.06041   -2.91397  19.16223 1.000 9.76579  ? 178 ARG A C    1 
ATOM   2393 O  O    . ARG A 1 155 ? 5.89749   -3.06659  17.94635 1.000 10.13399 ? 178 ARG A O    1 
ATOM   2394 C  CB   . ARG A 1 155 ? 7.10256   -0.69713  19.58425 1.000 10.84851 ? 178 ARG A CB   1 
ATOM   2395 C  CG   . ARG A 1 155 ? 8.07940   0.10979   20.42621 1.000 11.91256 ? 178 ARG A CG   1 
ATOM   2396 C  CD   . ARG A 1 155 ? 7.89405   1.60136   20.23807 1.000 12.51609 ? 178 ARG A CD   1 
ATOM   2397 N  NE   . ARG A 1 155 ? 8.26293   2.00185   18.88942 1.000 12.36090 ? 178 ARG A NE   1 
ATOM   2398 C  CZ   . ARG A 1 155 ? 8.22983   3.24581   18.43889 1.000 13.22845 ? 178 ARG A CZ   1 
ATOM   2399 N  NH1  . ARG A 1 155 ? 7.87471   4.25217   19.21610 1.000 12.87912 ? 178 ARG A NH1  1 
ATOM   2400 N  NH2  . ARG A 1 155 ? 8.57158   3.48482   17.17549 1.000 13.70100 ? 178 ARG A NH2  1 
ATOM   2401 H  H    . ARG A 1 155 ? 8.90704   -2.02695  18.59347 1.000 13.46285 ? 178 ARG A H    1 
ATOM   2402 H  HA   . ARG A 1 155 ? 7.37034   -2.41132  20.65974 1.000 12.17938 ? 178 ARG A HA   1 
ATOM   2403 H  HB2  . ARG A 1 155 ? 7.23380   -0.44733  18.65620 1.000 13.01822 ? 178 ARG A HB2  1 
ATOM   2404 H  HB3  . ARG A 1 155 ? 6.20432   -0.46413  19.86670 1.000 13.01822 ? 178 ARG A HB3  1 
ATOM   2405 H  HG2  . ARG A 1 155 ? 7.93934   -0.09673  21.36356 1.000 14.29507 ? 178 ARG A HG2  1 
ATOM   2406 H  HG3  . ARG A 1 155 ? 8.98651   -0.11735  20.16839 1.000 14.29507 ? 178 ARG A HG3  1 
ATOM   2407 H  HD2  . ARG A 1 155 ? 6.96355   1.83295   20.38446 1.000 15.01930 ? 178 ARG A HD2  1 
ATOM   2408 H  HD3  . ARG A 1 155 ? 8.45770   2.07940   20.86631 1.000 15.01930 ? 178 ARG A HD3  1 
ATOM   2409 H  HE   . ARG A 1 155 ? 8.52076   1.38687   18.34635 1.000 14.83308 ? 178 ARG A HE   1 
ATOM   2410 H  HH11 . ARG A 1 155 ? 7.65803   4.10693   20.03559 1.000 15.45494 ? 178 ARG A HH11 1 
ATOM   2411 H  HH12 . ARG A 1 155 ? 7.86007   5.05298   18.90291 1.000 15.45494 ? 178 ARG A HH12 1 
ATOM   2412 H  HH21 . ARG A 1 155 ? 8.80964   2.83556   16.66424 1.000 16.44120 ? 178 ARG A HH21 1 
ATOM   2413 H  HH22 . ARG A 1 155 ? 8.55442   4.28859   16.87009 1.000 16.44120 ? 178 ARG A HH22 1 
ATOM   2414 N  N    . ASP A 1 156 ? 5.16604   -3.32074  20.06789 1.000 9.18668  ? 179 ASP A N    1 
ATOM   2415 C  CA   . ASP A 1 156 ? 3.86330   -3.85072  19.66104 1.000 9.02032  ? 179 ASP A CA   1 
ATOM   2416 C  C    . ASP A 1 156 ? 4.00117   -5.08802  18.78378 1.000 9.04727  ? 179 ASP A C    1 
ATOM   2417 O  O    . ASP A 1 156 ? 3.25740   -5.26838  17.80879 1.000 9.47575  ? 179 ASP A O    1 
ATOM   2418 C  CB   . ASP A 1 156 ? 3.03237   -2.75775  18.99304 1.000 9.05168  ? 179 ASP A CB   1 
ATOM   2419 C  CG   . ASP A 1 156 ? 3.00606   -1.48615  19.81828 1.000 9.47495  ? 179 ASP A CG   1 
ATOM   2420 O  OD1  . ASP A 1 156 ? 2.44127   -1.54352  20.93943 1.000 10.05028 ? 179 ASP A OD1  1 
ATOM   2421 O  OD2  . ASP A 1 156 ? 3.58057   -0.46809  19.38402 1.000 10.49700 ? 179 ASP A OD2  1 
ATOM   2422 H  H    . ASP A 1 156 ? 5.29064   -3.29944  20.91854 1.000 11.02401 ? 179 ASP A H    1 
ATOM   2423 H  HA   . ASP A 1 156 ? 3.38325   -4.14543  20.45072 1.000 10.82438 ? 179 ASP A HA   1 
ATOM   2424 H  HB2  . ASP A 1 156 ? 3.41523   -2.54974  18.12641 1.000 10.86201 ? 179 ASP A HB2  1 
ATOM   2425 H  HB3  . ASP A 1 156 ? 2.12014   -3.06980  18.88646 1.000 10.86201 ? 179 ASP A HB3  1 
ATOM   2426 N  N    . THR A 1 157 ? 4.93992   -5.96284  19.15904 1.000 9.15085  ? 180 THR A N    1 
ATOM   2427 C  CA   . THR A 1 157 ? 5.22059   -7.16794  18.40903 1.000 9.18719  ? 180 THR A CA   1 
ATOM   2428 C  C    . THR A 1 157 ? 5.00223   -8.41511  19.26460 1.000 9.09400  ? 180 THR A C    1 
ATOM   2429 O  O    . THR A 1 157 ? 5.03403   -8.38633  20.49930 1.000 9.32570  ? 180 THR A O    1 
ATOM   2430 C  CB   . THR A 1 157 ? 6.65707   -7.22278  17.87278 1.000 9.55443  ? 180 THR A CB   1 
ATOM   2431 O  OG1  . THR A 1 157 ? 7.58379   -7.21947  18.97067 1.000 10.28524 ? 180 THR A OG1  1 
ATOM   2432 C  CG2  . THR A 1 157 ? 6.94523   -6.10206  16.90374 1.000 10.00591 ? 180 THR A CG2  1 
ATOM   2433 H  H    . THR A 1 157 ? 5.43079   -5.86910  19.85893 1.000 10.98102 ? 180 THR A H    1 
ATOM   2434 H  HA   . THR A 1 157 ? 4.60336   -7.17398  17.66077 1.000 11.02463 ? 180 THR A HA   1 
ATOM   2435 H  HB   . THR A 1 157 ? 6.77739   -8.04365  17.37018 1.000 11.46532 ? 180 THR A HB   1 
ATOM   2436 H  HG1  . THR A 1 157 ? 7.55706   -6.47931  19.36697 1.000 12.34229 ? 180 THR A HG1  1 
ATOM   2437 H  HG21 . THR A 1 157 ? 7.83518   -6.20552  16.53201 1.000 12.00709 ? 180 THR A HG21 1 
ATOM   2438 H  HG22 . THR A 1 157 ? 6.29870   -6.11419  16.18073 1.000 12.00709 ? 180 THR A HG22 1 
ATOM   2439 H  HG23 . THR A 1 157 ? 6.89183   -5.24747  17.35950 1.000 12.00709 ? 180 THR A HG23 1 
ATOM   2440 N  N    . THR A 1 158 ? 4.84430   -9.53633  18.57156 1.000 9.37254  ? 181 THR A N    1 
ATOM   2441 C  CA   . THR A 1 158 ? 4.98970   -10.83926 19.17793 1.000 9.31350  ? 181 THR A CA   1 
ATOM   2442 C  C    . THR A 1 158 ? 5.47197   -11.79774 18.10034 1.000 9.58798  ? 181 THR A C    1 
ATOM   2443 O  O    . THR A 1 158 ? 5.66694   -11.40288 16.94334 1.000 10.23957 ? 181 THR A O    1 
ATOM   2444 C  CB   . THR A 1 158 ? 3.69845   -11.30758 19.86483 1.000 8.91631  ? 181 THR A CB   1 
ATOM   2445 O  OG1  . THR A 1 158 ? 4.05180   -12.39671 20.71574 1.000 9.12467  ? 181 THR A OG1  1 
ATOM   2446 C  CG2  . THR A 1 158 ? 2.64021   -11.72266 18.84228 1.000 9.60772  ? 181 THR A CG2  1 
ATOM   2447 H  H    . THR A 1 158 ? 4.64932   -9.56252  17.73437 1.000 11.24705 ? 181 THR A H    1 
ATOM   2448 H  HA   . THR A 1 158 ? 5.66482   -10.79710 19.87316 1.000 11.17620 ? 181 THR A HA   1 
ATOM   2449 H  HB   . THR A 1 158 ? 3.29488   -10.59326 20.38229 1.000 10.69957 ? 181 THR A HB   1 
ATOM   2450 H  HG1  . THR A 1 158 ? 3.37552   -12.66383 21.13633 1.000 10.94961 ? 181 THR A HG1  1 
ATOM   2451 H  HG21 . THR A 1 158 ? 1.77362   -11.79435 19.27214 1.000 11.52926 ? 181 THR A HG21 1 
ATOM   2452 H  HG22 . THR A 1 158 ? 2.58650   -11.06234 18.13376 1.000 11.52926 ? 181 THR A HG22 1 
ATOM   2453 H  HG23 . THR A 1 158 ? 2.87166   -12.58149 18.45530 1.000 11.52926 ? 181 THR A HG23 1 
ATOM   2454 N  N    . SER A 1 159 ? 5.65108   -13.06165 18.47522 1.000 9.61997  ? 182 SER A N    1 
ATOM   2455 C  CA   . SER A 1 159 ? 6.00351   -14.07655 17.49027 1.000 9.77875  ? 182 SER A CA   1 
ATOM   2456 C  C    . SER A 1 159 ? 4.79678   -14.93894 17.17018 1.000 9.68887  ? 182 SER A C    1 
ATOM   2457 O  O    . SER A 1 159 ? 3.87040   -15.05328 17.98513 1.000 9.69833  ? 182 SER A O    1 
ATOM   2458 C  CB   . SER A 1 159 ? 7.12318   -14.97688 18.02199 1.000 10.26650 ? 182 SER A CB   1 
ATOM   2459 O  OG   . SER A 1 159 ? 6.61472   -15.78638 19.06356 1.000 11.27815 ? 182 SER A OG   1 
ATOM   2460 H  H    . SER A 1 159 ? 5.57484   -13.34951 19.28202 1.000 11.54396 ? 182 SER A H    1 
ATOM   2461 H  HA   . SER A 1 159 ? 6.31437   -13.64315 16.68006 1.000 11.73450 ? 182 SER A HA   1 
ATOM   2462 H  HB2  . SER A 1 159 ? 7.44995   -15.54230 17.30476 1.000 12.31979 ? 182 SER A HB2  1 
ATOM   2463 H  HB3  . SER A 1 159 ? 7.84419   -14.42595 18.36483 1.000 12.31979 ? 182 SER A HB3  1 
ATOM   2464 H  HG   . SER A 1 159 ? 7.24367   -16.19088 19.44618 1.000 13.53378 ? 182 SER A HG   1 
ATOM   2465 N  N    . PRO A 1 160 ? 4.77705   -15.57734 15.98862 1.000 9.40407  ? 183 PRO A N    1 
ATOM   2466 C  CA   . PRO A 1 160 ? 3.66440   -16.48697 15.68305 1.000 9.94251  ? 183 PRO A CA   1 
ATOM   2467 C  C    . PRO A 1 160 ? 3.51898   -17.59046 16.71011 1.000 9.84735  ? 183 PRO A C    1 
ATOM   2468 O  O    . PRO A 1 160 ? 2.39489   -17.90768 17.11128 1.000 10.14417 ? 183 PRO A O    1 
ATOM   2469 C  CB   . PRO A 1 160 ? 4.00582   -17.00249 14.27673 1.000 10.29956 ? 183 PRO A CB   1 
ATOM   2470 C  CG   . PRO A 1 160 ? 4.82214   -15.89956 13.66446 1.000 10.29465 ? 183 PRO A CG   1 
ATOM   2471 C  CD   . PRO A 1 160 ? 5.64635   -15.34643 14.81726 1.000 9.90975  ? 183 PRO A CD   1 
ATOM   2472 H  HA   . PRO A 1 160 ? 2.82771   -15.99956 15.62570 1.000 11.93101 ? 183 PRO A HA   1 
ATOM   2473 H  HB2  . PRO A 1 160 ? 4.51832   -17.82372 14.33857 1.000 12.35947 ? 183 PRO A HB2  1 
ATOM   2474 H  HB3  . PRO A 1 160 ? 3.19194   -17.15654 13.77199 1.000 12.35947 ? 183 PRO A HB3  1 
ATOM   2475 H  HG2  . PRO A 1 160 ? 5.39437   -16.25737 12.96774 1.000 12.35358 ? 183 PRO A HG2  1 
ATOM   2476 H  HG3  . PRO A 1 160 ? 4.23749   -15.21863 13.29647 1.000 12.35358 ? 183 PRO A HG3  1 
ATOM   2477 H  HD2  . PRO A 1 160 ? 6.48343   -15.82826 14.90691 1.000 11.89170 ? 183 PRO A HD2  1 
ATOM   2478 H  HD3  . PRO A 1 160 ? 5.81979   -14.39980 14.69599 1.000 11.89170 ? 183 PRO A HD3  1 
ATOM   2479 N  N    . ARG A 1 161 ? 4.62452   -18.18703 17.14415 1.000 10.67731 ? 184 ARG A N    1 
ATOM   2480 C  CA   . ARG A 1 161 ? 4.55027   -19.26547 18.12290 1.000 11.15835 ? 184 ARG A CA   1 
ATOM   2481 C  C    . ARG A 1 161 ? 3.90247   -18.79274 19.41836 1.000 10.62435 ? 184 ARG A C    1 
ATOM   2482 O  O    . ARG A 1 161 ? 3.01347   -19.45735 19.97785 1.000 10.31876 ? 184 ARG A O    1 
ATOM   2483 C  CB   . ARG A 1 161 ? 5.94472   -19.81534 18.41562 1.000 13.23653 ? 184 ARG A CB   1 
ATOM   2484 C  CG   . ARG A 1 161 ? 5.94602   -20.98837 19.37409 1.000 15.33908 ? 184 ARG A CG   1 
ATOM   2485 C  CD   . ARG A 1 161 ? 7.33790   -21.26088 19.97391 1.000 17.05981 ? 184 ARG A CD   1 
ATOM   2486 N  NE   . ARG A 1 161 ? 8.38421   -21.53841 18.99468 1.000 18.08972 ? 184 ARG A NE   1 
ATOM   2487 C  CZ   . ARG A 1 161 ? 8.79571   -22.74832 18.64409 1.000 19.22359 ? 184 ARG A CZ   1 
ATOM   2488 N  NH1  . ARG A 1 161 ? 8.20217   -23.84154 19.09163 1.000 21.48597 ? 184 ARG A NH1  1 
ATOM   2489 N  NH2  . ARG A 1 161 ? 9.83305   -22.86357 17.82319 1.000 18.70173 ? 184 ARG A NH2  1 
ATOM   2490 H  H    . ARG A 1 161 ? 5.42209   -17.98880 16.89082 1.000 12.81278 ? 184 ARG A H    1 
ATOM   2491 H  HA   . ARG A 1 161 ? 4.01007   -19.97738 17.74573 1.000 13.39002 ? 184 ARG A HA   1 
ATOM   2492 H  HB2  . ARG A 1 161 ? 6.34451   -20.11202 17.58312 1.000 15.88383 ? 184 ARG A HB2  1 
ATOM   2493 H  HB3  . ARG A 1 161 ? 6.48223   -19.11019 18.80901 1.000 15.88383 ? 184 ARG A HB3  1 
ATOM   2494 H  HG2  . ARG A 1 161 ? 5.33567   -20.80172 20.10452 1.000 18.40690 ? 184 ARG A HG2  1 
ATOM   2495 H  HG3  . ARG A 1 161 ? 5.66212   -21.78557 18.89999 1.000 18.40690 ? 184 ARG A HG3  1 
ATOM   2496 H  HD2  . ARG A 1 161 ? 7.61327   -20.48090 20.48056 1.000 20.47177 ? 184 ARG A HD2  1 
ATOM   2497 H  HD3  . ARG A 1 161 ? 7.27566   -22.03178 20.55936 1.000 20.47177 ? 184 ARG A HD3  1 
ATOM   2498 H  HE   . ARG A 1 161 ? 8.76259   -20.86517 18.61629 1.000 21.70766 ? 184 ARG A HE   1 
ATOM   2499 H  HH11 . ARG A 1 161 ? 7.53036   -23.77851 19.62482 1.000 25.78317 ? 184 ARG A HH11 1 
ATOM   2500 H  HH12 . ARG A 1 161 ? 8.48787   -24.61574 18.84957 1.000 25.78317 ? 184 ARG A HH12 1 
ATOM   2501 H  HH21 . ARG A 1 161 ? 10.22746  -22.15903 17.52711 1.000 22.44207 ? 184 ARG A HH21 1 
ATOM   2502 H  HH22 . ARG A 1 161 ? 10.11049  -23.64276 17.58761 1.000 22.44207 ? 184 ARG A HH22 1 
ATOM   2503 N  N    . ALA A 1 162 ? 4.34678   -17.65066 19.92751 1.000 10.24312 ? 185 ALA A N    1 
ATOM   2504 C  CA   . ALA A 1 162 ? 3.82912   -17.20172 21.20849 1.000 10.40923 ? 185 ALA A CA   1 
ATOM   2505 C  C    . ALA A 1 162 ? 2.35743   -16.85998 21.09695 1.000 9.85619  ? 185 ALA A C    1 
ATOM   2506 O  O    . ALA A 1 162 ? 1.57221   -17.18031 21.99026 1.000 10.03984 ? 185 ALA A O    1 
ATOM   2507 C  CB   . ALA A 1 162 ? 4.59455   -15.98857 21.71855 1.000 11.27039 ? 185 ALA A CB   1 
ATOM   2508 H  H    . ALA A 1 162 ? 4.92924   -17.13397 19.56232 1.000 12.29175 ? 185 ALA A H    1 
ATOM   2509 H  HA   . ALA A 1 162 ? 3.95061   -17.91892 21.85018 1.000 12.49108 ? 185 ALA A HA   1 
ATOM   2510 H  HB1  . ALA A 1 162 ? 4.21474   -15.70900 22.56618 1.000 13.52447 ? 185 ALA A HB1  1 
ATOM   2511 H  HB2  . ALA A 1 162 ? 5.52646   -16.23015 21.83726 1.000 13.52447 ? 185 ALA A HB2  1 
ATOM   2512 H  HB3  . ALA A 1 162 ? 4.51878   -15.27161 21.06960 1.000 13.52447 ? 185 ALA A HB3  1 
ATOM   2513 N  N    . MET A 1 163 ? 1.96254   -16.21409 20.00502 1.000 9.72722  ? 186 MET A N    1 
ATOM   2514 C  CA   . MET A 1 163 ? 0.57526   -15.81041 19.88670 1.000 9.11947  ? 186 MET A CA   1 
ATOM   2515 C  C    . MET A 1 163 ? -0.32583  -17.01322 19.67869 1.000 8.93174  ? 186 MET A C    1 
ATOM   2516 O  O    . MET A 1 163 ? -1.46966  -17.02118 20.15651 1.000 9.70729  ? 186 MET A O    1 
ATOM   2517 C  CB   . MET A 1 163 ? 0.39188   -14.77878 18.78520 1.000 9.68198  ? 186 MET A CB   1 
ATOM   2518 C  CG   . MET A 1 163 ? -0.98018  -14.07708 18.79154 1.000 9.99494  ? 186 MET A CG   1 
ATOM   2519 S  SD   . MET A 1 163 ? -1.23295  -13.10858 20.30503 1.000 11.13208 ? 186 MET A SD   1 
ATOM   2520 C  CE   . MET A 1 163 ? -2.52550  -13.95214 21.20081 1.000 14.51268 ? 186 MET A CE   1 
ATOM   2521 H  H    . MET A 1 163 ? 2.46561   -16.00506 19.33956 1.000 11.67266 ? 186 MET A H    1 
ATOM   2522 H  HA   . MET A 1 163 ? 0.31814   -15.37001 20.71183 1.000 10.94336 ? 186 MET A HA   1 
ATOM   2523 H  HB2  . MET A 1 163 ? 1.07181   -14.09438 18.88619 1.000 11.61837 ? 186 MET A HB2  1 
ATOM   2524 H  HB3  . MET A 1 163 ? 0.49117   -15.22108 17.92763 1.000 11.61837 ? 186 MET A HB3  1 
ATOM   2525 H  HG2  . MET A 1 163 ? -1.03540  -13.47552 18.03260 1.000 11.99393 ? 186 MET A HG2  1 
ATOM   2526 H  HG3  . MET A 1 163 ? -1.68142  -14.74507 18.73711 1.000 11.99393 ? 186 MET A HG3  1 
ATOM   2527 H  HE1  . MET A 1 163 ? -2.70512  -13.47112 22.02376 1.000 17.41521 ? 186 MET A HE1  1 
ATOM   2528 H  HE2  . MET A 1 163 ? -3.32478  -13.97846 20.65186 1.000 17.41521 ? 186 MET A HE2  1 
ATOM   2529 H  HE3  . MET A 1 163 ? -2.23279  -14.85469 21.40237 1.000 17.41521 ? 186 MET A HE3  1 
ATOM   2530 N  N    . ALA A 1 164 ? 0.14640   -18.02354 18.94068 1.000 9.21171  ? 187 ALA A N    1 
ATOM   2531 C  CA   . ALA A 1 164 ? -0.66861  -19.22683 18.78982 1.000 8.89577  ? 187 ALA A CA   1 
ATOM   2532 C  C    . ALA A 1 164 ? -0.86796  -19.91571 20.13487 1.000 8.85059  ? 187 ALA A C    1 
ATOM   2533 O  O    . ALA A 1 164 ? -1.97479  -20.33468 20.47506 1.000 9.46035  ? 187 ALA A O    1 
ATOM   2534 C  CB   . ALA A 1 164 ? -0.02661  -20.17770 17.78972 1.000 9.47385  ? 187 ALA A CB   1 
ATOM   2535 H  H    A ALA A 1 164 ? 0.90438   -18.03481 18.53455 0.290 11.05406 ? 187 ALA A H    1 
ATOM   2536 H  H    B ALA A 1 164 ? 0.90438   -18.03481 18.53455 0.710 11.05406 ? 187 ALA A H    1 
ATOM   2537 H  HA   . ALA A 1 164 ? -1.53837  -18.97442 18.44240 1.000 10.67492 ? 187 ALA A HA   1 
ATOM   2538 H  HB1  . ALA A 1 164 ? -0.61185  -20.94000 17.65820 1.000 11.36862 ? 187 ALA A HB1  1 
ATOM   2539 H  HB2  . ALA A 1 164 ? 0.10318   -19.71141 16.94910 1.000 11.36862 ? 187 ALA A HB2  1 
ATOM   2540 H  HB3  . ALA A 1 164 ? 0.82846   -20.47357 18.13932 1.000 11.36862 ? 187 ALA A HB3  1 
ATOM   2541 N  N    . GLN A 1 165 ? 0.21297   -20.07245 20.90459 1.000 9.31009  ? 188 GLN A N    1 
ATOM   2542 C  CA   . GLN A 1 165 ? 0.08898   -20.74014 22.19361 1.000 9.73629  ? 188 GLN A CA   1 
ATOM   2543 C  C    . GLN A 1 165 ? -0.80568  -19.93970 23.13288 1.000 9.36337  ? 188 GLN A C    1 
ATOM   2544 O  O    . GLN A 1 165 ? -1.65599  -20.50603 23.83558 1.000 10.13776 ? 188 GLN A O    1 
ATOM   2545 C  CB   . GLN A 1 165 ? 1.47831   -20.93246 22.80051 1.000 11.18278 ? 188 GLN A CB   1 
ATOM   2546 C  CG   . GLN A 1 165 ? 2.31393   -21.95400 22.05864 1.000 12.08213 ? 188 GLN A CG   1 
ATOM   2547 C  CD   . GLN A 1 165 ? 1.81907   -23.38893 22.23089 1.000 14.05004 ? 188 GLN A CD   1 
ATOM   2548 O  OE1  . GLN A 1 165 ? 1.02001   -23.69403 23.10611 1.000 15.58798 ? 188 GLN A OE1  1 
ATOM   2549 N  NE2  . GLN A 1 165 ? 2.28836   -24.27338 21.36669 1.000 16.66059 ? 188 GLN A NE2  1 
ATOM   2550 H  H    . GLN A 1 165 ? 1.00661   -19.80731 20.70600 1.000 11.17210 ? 188 GLN A H    1 
ATOM   2551 H  HA   . GLN A 1 165 ? -0.31220  -21.61474 22.07097 1.000 11.68355 ? 188 GLN A HA   1 
ATOM   2552 H  HB2  . GLN A 1 165 ? 1.95128   -20.08588 22.77773 1.000 13.41933 ? 188 GLN A HB2  1 
ATOM   2553 H  HB3  . GLN A 1 165 ? 1.38188   -21.23404 23.71738 1.000 13.41933 ? 188 GLN A HB3  1 
ATOM   2554 H  HG2  . GLN A 1 165 ? 2.29502   -21.74552 21.11150 1.000 14.49855 ? 188 GLN A HG2  1 
ATOM   2555 H  HG3  . GLN A 1 165 ? 3.22491   -21.91282 22.38929 1.000 14.49855 ? 188 GLN A HG3  1 
ATOM   2556 H  HE21 . GLN A 1 165 ? 2.83884   -24.02577 20.75411 1.000 19.99271 ? 188 GLN A HE21 1 
ATOM   2557 H  HE22 . GLN A 1 165 ? 2.04301   -25.09608 21.41735 1.000 19.99271 ? 188 GLN A HE22 1 
ATOM   2558 N  N    . THR A 1 166 ? -0.67063  -18.61994 23.12935 1.000 9.56734  ? 189 THR A N    1 
ATOM   2559 C  CA   . THR A 1 166 ? -1.52596  -17.80658 23.98209 1.000 9.62761  ? 189 THR A CA   1 
ATOM   2560 C  C    . THR A 1 166 ? -2.96740  -17.82362 23.52299 1.000 9.41205  ? 189 THR A C    1 
ATOM   2561 O  O    . THR A 1 166 ? -3.87776  -17.90816 24.34658 1.000 9.64765  ? 189 THR A O    1 
ATOM   2562 C  CB   . THR A 1 166 ? -0.97587  -16.39450 24.09687 1.000 10.57562 ? 189 THR A CB   1 
ATOM   2563 O  OG1  . THR A 1 166 ? 0.28827   -16.49257 24.74914 1.000 10.53216 ? 189 THR A OG1  1 
ATOM   2564 C  CG2  . THR A 1 166 ? -1.89764  -15.48420 24.87828 1.000 12.21719 ? 189 THR A CG2  1 
ATOM   2565 H  H    . THR A 1 166 ? -0.10497  -18.17992 22.65394 1.000 11.48081 ? 189 THR A H    1 
ATOM   2566 H  HA   . THR A 1 166 ? -1.51799  -18.18383 24.87568 1.000 11.55313 ? 189 THR A HA   1 
ATOM   2567 H  HB   . THR A 1 166 ? -0.88852  -15.99219 23.21857 1.000 12.69075 ? 189 THR A HB   1 
ATOM   2568 H  HG1  . THR A 1 166 ? 0.67576   -15.74736 24.73823 1.000 12.63859 ? 189 THR A HG1  1 
ATOM   2569 H  HG21 . THR A 1 166 ? -1.43985  -14.65767 25.09777 1.000 14.66063 ? 189 THR A HG21 1 
ATOM   2570 H  HG22 . THR A 1 166 ? -2.68506  -15.27746 24.35090 1.000 14.66063 ? 189 THR A HG22 1 
ATOM   2571 H  HG23 . THR A 1 166 ? -2.17440  -15.91862 25.70021 1.000 14.66063 ? 189 THR A HG23 1 
ATOM   2572 N  N    . LEU A 1 167 ? -3.21077  -17.72859 22.21231 1.000 10.17731 ? 190 LEU A N    1 
ATOM   2573 C  CA   . LEU A 1 167 ? -4.59674  -17.82489 21.75290 1.000 9.93228  ? 190 LEU A CA   1 
ATOM   2574 C  C    . LEU A 1 167 ? -5.19916  -19.17506 22.12389 1.000 10.04806 ? 190 LEU A C    1 
ATOM   2575 O  O    . LEU A 1 167 ? -6.36749  -19.25187 22.51729 1.000 10.81597 ? 190 LEU A O    1 
ATOM   2576 C  CB   . LEU A 1 167 ? -4.68782  -17.55914 20.25339 1.000 9.21979  ? 190 LEU A CB   1 
ATOM   2577 C  CG   . LEU A 1 167 ? -6.11152  -17.41991 19.71850 1.000 9.50240  ? 190 LEU A CG   1 
ATOM   2578 C  CD1  . LEU A 1 167 ? -6.82807  -16.21708 20.29792 1.000 11.56965 ? 190 LEU A CD1  1 
ATOM   2579 C  CD2  . LEU A 1 167 ? -6.14209  -17.33808 18.18408 1.000 9.83194  ? 190 LEU A CD2  1 
ATOM   2580 H  H    . LEU A 1 167 ? -2.61955  -17.61380 21.59841 1.000 12.21277 ? 190 LEU A H    1 
ATOM   2581 H  HA   . LEU A 1 167 ? -5.12303  -17.13678 22.18927 1.000 11.91874 ? 190 LEU A HA   1 
ATOM   2582 H  HB2  . LEU A 1 167 ? -4.21894  -16.73278 20.05801 1.000 11.06375 ? 190 LEU A HB2  1 
ATOM   2583 H  HB3  . LEU A 1 167 ? -4.26891  -18.29730 19.78377 1.000 11.06375 ? 190 LEU A HB3  1 
ATOM   2584 H  HG   . LEU A 1 167 ? -6.58656  -18.21882 19.99595 1.000 11.40288 ? 190 LEU A HG   1 
ATOM   2585 H  HD11 . LEU A 1 167 ? -7.72285  -16.17313 19.92598 1.000 13.88358 ? 190 LEU A HD11 1 
ATOM   2586 H  HD12 . LEU A 1 167 ? -6.87494  -16.31166 21.26216 1.000 13.88358 ? 190 LEU A HD12 1 
ATOM   2587 H  HD13 . LEU A 1 167 ? -6.33445  -15.41438 20.06789 1.000 13.88358 ? 190 LEU A HD13 1 
ATOM   2588 H  HD21 . LEU A 1 167 ? -7.06219  -17.24628 17.89100 1.000 11.79832 ? 190 LEU A HD21 1 
ATOM   2589 H  HD22 . LEU A 1 167 ? -5.62561  -16.56826 17.89854 1.000 11.79832 ? 190 LEU A HD22 1 
ATOM   2590 H  HD23 . LEU A 1 167 ? -5.75732  -18.14924 17.81684 1.000 11.79832 ? 190 LEU A HD23 1 
ATOM   2591 N  N    A ARG A 1 168 ? -4.41283  -20.24771 22.03163 0.721 10.48642 ? 191 ARG A N    1 
ATOM   2592 N  N    B ARG A 1 168 ? -4.41101  -20.24639 22.04855 0.279 11.06288 ? 191 ARG A N    1 
ATOM   2593 C  CA   A ARG A 1 168 ? -4.91467  -21.54508 22.46598 0.721 10.60812 ? 191 ARG A CA   1 
ATOM   2594 C  CA   B ARG A 1 168 ? -4.92114  -21.54824 22.46451 0.279 12.17256 ? 191 ARG A CA   1 
ATOM   2595 C  C    A ARG A 1 168 ? -5.32461  -21.49257 23.93374 0.721 11.09488 ? 191 ARG A C    1 
ATOM   2596 C  C    B ARG A 1 168 ? -5.30189  -21.53772 23.94063 0.279 11.40731 ? 191 ARG A C    1 
ATOM   2597 O  O    A ARG A 1 168 ? -6.40297  -21.95351 24.31102 0.721 11.62121 ? 191 ARG A O    1 
ATOM   2598 O  O    B ARG A 1 168 ? -6.34321  -22.07584 24.32811 0.279 11.19830 ? 191 ARG A O    1 
ATOM   2599 C  CB   A ARG A 1 168 ? -3.86414  -22.63265 22.26083 0.721 11.31318 ? 191 ARG A CB   1 
ATOM   2600 C  CB   B ARG A 1 168 ? -3.87646  -22.62795 22.20041 0.279 14.49701 ? 191 ARG A CB   1 
ATOM   2601 C  CG   A ARG A 1 168 ? -4.40467  -24.00611 22.60111 0.721 12.49984 ? 191 ARG A CG   1 
ATOM   2602 C  CG   B ARG A 1 168 ? -4.45914  -24.02022 22.16167 0.279 17.28943 ? 191 ARG A CG   1 
ATOM   2603 C  CD   A ARG A 1 168 ? -3.89941  -24.53182 23.90789 0.721 16.11211 ? 191 ARG A CD   1 
ATOM   2604 C  CD   B ARG A 1 168 ? -4.07812  -24.85144 23.36235 0.279 18.83509 ? 191 ARG A CD   1 
ATOM   2605 N  NE   A ARG A 1 168 ? -2.49715  -24.91688 23.78939 0.721 17.04755 ? 191 ARG A NE   1 
ATOM   2606 N  NE   B ARG A 1 168 ? -3.67042  -26.18738 22.93968 0.279 19.72282 ? 191 ARG A NE   1 
ATOM   2607 C  CZ   A ARG A 1 168 ? -2.06018  -26.02569 23.20293 0.721 17.89388 ? 191 ARG A CZ   1 
ATOM   2608 C  CZ   B ARG A 1 168 ? -2.41869  -26.53932 22.68069 0.279 20.02865 ? 191 ARG A CZ   1 
ATOM   2609 N  NH1  A ARG A 1 168 ? -2.90014  -26.95737 22.75302 0.721 18.82187 ? 191 ARG A NH1  1 
ATOM   2610 N  NH1  B ARG A 1 168 ? -1.41576  -25.69167 22.84282 0.279 20.87716 ? 191 ARG A NH1  1 
ATOM   2611 N  NH2  A ARG A 1 168 ? -0.74584  -26.20205 23.05902 0.721 18.00786 ? 191 ARG A NH2  1 
ATOM   2612 N  NH2  B ARG A 1 168 ? -2.16588  -27.77167 22.24902 0.279 17.01920 ? 191 ARG A NH2  1 
ATOM   2613 H  H    A ARG A 1 168 ? -3.60770  -20.24917 21.72937 0.721 12.58370 ? 191 ARG A H    1 
ATOM   2614 H  H    B ARG A 1 168 ? -3.59824  -20.24603 21.76747 0.279 13.27546 ? 191 ARG A H    1 
ATOM   2615 H  HA   A ARG A 1 168 ? -5.68601  -21.77123 21.92303 0.721 12.72974 ? 191 ARG A HA   1 
ATOM   2616 H  HA   B ARG A 1 168 ? -5.71220  -21.75598 21.94300 0.279 14.60707 ? 191 ARG A HA   1 
ATOM   2617 H  HB2  A ARG A 1 168 ? -3.58539  -22.63652 21.33175 0.721 13.57582 ? 191 ARG A HB2  1 
ATOM   2618 H  HB2  B ARG A 1 168 ? -3.45650  -22.45584 21.34314 0.279 17.39641 ? 191 ARG A HB2  1 
ATOM   2619 H  HB3  A ARG A 1 168 ? -3.10291  -22.45400 22.83485 0.721 13.57582 ? 191 ARG A HB3  1 
ATOM   2620 H  HB3  B ARG A 1 168 ? -3.21198  -22.60168 22.90658 0.279 17.39641 ? 191 ARG A HB3  1 
ATOM   2621 H  HG2  A ARG A 1 168 ? -5.37215  -23.95955 22.65317 0.721 14.99981 ? 191 ARG A HG2  1 
ATOM   2622 H  HG2  B ARG A 1 168 ? -5.42676  -23.95695 22.13711 0.279 20.74731 ? 191 ARG A HG2  1 
ATOM   2623 H  HG3  A ARG A 1 168 ? -4.13940  -24.62957 21.90698 0.721 14.99981 ? 191 ARG A HG3  1 
ATOM   2624 H  HG3  B ARG A 1 168 ? -4.13621  -24.47568 21.36846 0.279 20.74731 ? 191 ARG A HG3  1 
ATOM   2625 H  HD2  A ARG A 1 168 ? -3.97587  -23.84378 24.58734 0.721 19.33453 ? 191 ARG A HD2  1 
ATOM   2626 H  HD2  B ARG A 1 168 ? -3.33674  -24.43274 23.82705 0.279 22.60211 ? 191 ARG A HD2  1 
ATOM   2627 H  HD3  A ARG A 1 168 ? -4.41462  -25.31199 24.16632 0.721 19.33453 ? 191 ARG A HD3  1 
ATOM   2628 H  HD3  B ARG A 1 168 ? -4.83951  -24.93272 23.95781 0.279 22.60211 ? 191 ARG A HD3  1 
ATOM   2629 H  HE   A ARG A 1 168 ? -1.90931  -24.38605 24.12444 0.721 20.45706 ? 191 ARG A HE   1 
ATOM   2630 H  HE   B ARG A 1 168 ? -4.28217  -26.78557 22.85291 0.279 23.66739 ? 191 ARG A HE   1 
ATOM   2631 H  HH11 A ARG A 1 168 ? -3.74890  -26.84879 22.83907 0.721 22.58624 ? 191 ARG A HH11 1 
ATOM   2632 H  HH11 B ARG A 1 168 ? -1.56882  -24.89273 23.12185 0.279 25.05259 ? 191 ARG A HH11 1 
ATOM   2633 H  HH12 A ARG A 1 168 ? -2.59342  -27.66719 22.37662 0.721 22.58624 ? 191 ARG A HH12 1 
ATOM   2634 H  HH12 B ARG A 1 168 ? -0.61081  -25.93967 22.66918 0.279 25.05259 ? 191 ARG A HH12 1 
ATOM   2635 H  HH21 A ARG A 1 168 ? -0.19794  -25.60344 23.34376 0.721 21.60943 ? 191 ARG A HH21 1 
ATOM   2636 H  HH21 B ARG A 1 168 ? -2.81085  -28.33014 22.14078 0.279 20.42304 ? 191 ARG A HH21 1 
ATOM   2637 H  HH22 A ARG A 1 168 ? -0.44635  -26.91436 22.68150 0.721 21.60943 ? 191 ARG A HH22 1 
ATOM   2638 H  HH22 B ARG A 1 168 ? -1.35744  -28.01004 22.07813 0.279 20.42304 ? 191 ARG A HH22 1 
ATOM   2639 N  N    . ASN A 1 169 ? -4.46145  -20.93382 24.77877 1.000 10.62482 ? 192 ASN A N    1 
ATOM   2640 C  CA   . ASN A 1 169 ? -4.74401  -20.83121 26.20925 1.000 10.68507 ? 192 ASN A CA   1 
ATOM   2641 C  C    . ASN A 1 169 ? -6.03637  -20.07428 26.46149 1.000 10.42923 ? 192 ASN A C    1 
ATOM   2642 O  O    . ASN A 1 169 ? -6.87541  -20.48697 27.26465 1.000 12.33297 ? 192 ASN A O    1 
ATOM   2643 C  CB   . ASN A 1 169 ? -3.55172  -20.12561 26.85179 1.000 11.06922 ? 192 ASN A CB   1 
ATOM   2644 C  CG   . ASN A 1 169 ? -3.58361  -20.14138 28.31711 1.000 14.22242 ? 192 ASN A CG   1 
ATOM   2645 O  OD1  . ASN A 1 169 ? -4.38661  -20.84871 28.93284 1.000 15.82012 ? 192 ASN A OD1  1 
ATOM   2646 N  ND2  . ASN A 1 169 ? -2.68429  -19.37514 28.91379 1.000 15.94700 ? 192 ASN A ND2  1 
ATOM   2647 H  H    A ASN A 1 169 ? -3.70080  -20.60428 24.54980 0.721 12.74978 ? 192 ASN A H    1 
ATOM   2648 H  H    B ASN A 1 169 ? -3.71672  -20.57307 24.54459 0.279 12.74978 ? 192 ASN A H    1 
ATOM   2649 H  HA   . ASN A 1 169 ? -4.85652  -21.70994 26.60433 1.000 12.82208 ? 192 ASN A HA   1 
ATOM   2650 H  HB2  . ASN A 1 169 ? -2.73610  -20.56729 26.56791 1.000 13.28306 ? 192 ASN A HB2  1 
ATOM   2651 H  HB3  . ASN A 1 169 ? -3.54430  -19.19900 26.56504 1.000 13.28306 ? 192 ASN A HB3  1 
ATOM   2652 H  HD21 . ASN A 1 169 ? -2.65086  -19.34024 29.77243 1.000 19.13640 ? 192 ASN A HD21 1 
ATOM   2653 H  HD22 . ASN A 1 169 ? -2.13340  -18.91219 28.44284 1.000 19.13640 ? 192 ASN A HD22 1 
ATOM   2654 N  N    . LEU A 1 170 ? -6.21179  -18.95606 25.76443 1.000 9.88152  ? 193 LEU A N    1 
ATOM   2655 C  CA   . LEU A 1 170 ? -7.36292  -18.09813 25.98803 1.000 10.36524 ? 193 LEU A CA   1 
ATOM   2656 C  C    . LEU A 1 170 ? -8.66717  -18.70127 25.49049 1.000 11.23161 ? 193 LEU A C    1 
ATOM   2657 O  O    . LEU A 1 170 ? -9.70426  -18.49670 26.11871 1.000 11.79105 ? 193 LEU A O    1 
ATOM   2658 C  CB   . LEU A 1 170 ? -7.15367  -16.76041 25.26638 1.000 10.75941 ? 193 LEU A CB   1 
ATOM   2659 C  CG   . LEU A 1 170 ? -6.07704  -15.83201 25.83482 1.000 11.40964 ? 193 LEU A CG   1 
ATOM   2660 C  CD1  . LEU A 1 170 ? -5.87539  -14.64115 24.92212 1.000 12.80015 ? 193 LEU A CD1  1 
ATOM   2661 C  CD2  . LEU A 1 170 ? -6.44811  -15.39726 27.23761 1.000 12.75308 ? 193 LEU A CD2  1 
ATOM   2662 H  H    . LEU A 1 170 ? -5.67615  -18.67200 25.15451 1.000 11.85782 ? 193 LEU A H    1 
ATOM   2663 H  HA   . LEU A 1 170 ? -7.43478  -17.96706 26.94645 1.000 12.43829 ? 193 LEU A HA   1 
ATOM   2664 H  HB2  . LEU A 1 170 ? -6.90805  -16.95102 24.34756 1.000 12.91129 ? 193 LEU A HB2  1 
ATOM   2665 H  HB3  . LEU A 1 170 ? -7.99158  -16.27238 25.29138 1.000 12.91129 ? 193 LEU A HB3  1 
ATOM   2666 H  HG   . LEU A 1 170 ? -5.23229  -16.30579 25.88812 1.000 13.69156 ? 193 LEU A HG   1 
ATOM   2667 H  HD11 . LEU A 1 170 ? -5.20962  -14.05341 25.31226 1.000 15.36018 ? 193 LEU A HD11 1 
ATOM   2668 H  HD12 . LEU A 1 170 ? -5.57252  -14.95501 24.05571 1.000 15.36018 ? 193 LEU A HD12 1 
ATOM   2669 H  HD13 . LEU A 1 170 ? -6.71782  -14.16978 24.82720 1.000 15.36018 ? 193 LEU A HD13 1 
ATOM   2670 H  HD21 . LEU A 1 170 ? -5.78785  -14.76221 27.55646 1.000 15.30369 ? 193 LEU A HD21 1 
ATOM   2671 H  HD22 . LEU A 1 170 ? -7.32434  -14.98165 27.21803 1.000 15.30369 ? 193 LEU A HD22 1 
ATOM   2672 H  HD23 . LEU A 1 170 ? -6.46422  -16.17600 27.81571 1.000 15.30369 ? 193 LEU A HD23 1 
ATOM   2673 N  N    . THR A 1 171 ? -8.65005  -19.38173 24.33896 1.000 11.66331 ? 194 THR A N    1 
ATOM   2674 C  CA   . THR A 1 171 ? -9.87773  -19.83403 23.69595 1.000 12.42347 ? 194 THR A CA   1 
ATOM   2675 C  C    . THR A 1 171 ? -10.19411 -21.30004 23.93464 1.000 13.65624 ? 194 THR A C    1 
ATOM   2676 O  O    . THR A 1 171 ? -11.37340 -21.65845 23.94554 1.000 17.15292 ? 194 THR A O    1 
ATOM   2677 C  CB   . THR A 1 171 ? -9.84878  -19.58885 22.17622 1.000 13.31062 ? 194 THR A CB   1 
ATOM   2678 O  OG1  . THR A 1 171 ? -8.78833  -20.33611 21.55564 1.000 12.76861 ? 194 THR A OG1  1 
ATOM   2679 C  CG2  . THR A 1 171 ? -9.72217  -18.11478 21.87712 1.000 14.06823 ? 194 THR A CG2  1 
ATOM   2680 H  H    . THR A 1 171 ? -7.93374  -19.59239 23.91221 1.000 13.99597 ? 194 THR A H    1 
ATOM   2681 H  HA   . THR A 1 171 ? -10.60071 -19.30229 24.06398 1.000 14.90817 ? 194 THR A HA   1 
ATOM   2682 H  HB   . THR A 1 171 ? -10.68371 -19.89496 21.78881 1.000 15.97274 ? 194 THR A HB   1 
ATOM   2683 H  HG1  . THR A 1 171 ? -8.04915  -20.11695 21.88910 1.000 15.32233 ? 194 THR A HG1  1 
ATOM   2684 H  HG21 . THR A 1 171 ? -9.65165  -17.97536 20.91979 1.000 16.88187 ? 194 THR A HG21 1 
ATOM   2685 H  HG22 . THR A 1 171 ? -10.50143 -17.64106 22.20767 1.000 16.88187 ? 194 THR A HG22 1 
ATOM   2686 H  HG23 . THR A 1 171 ? -8.92996  -17.75594 22.30670 1.000 16.88187 ? 194 THR A HG23 1 
ATOM   2687 N  N    . LEU A 1 172 ? -9.18688  -22.15740 24.07738 1.000 12.66031 ? 195 LEU A N    1 
ATOM   2688 C  CA   . LEU A 1 172 ? -9.37275  -23.58737 24.27336 1.000 13.54260 ? 195 LEU A CA   1 
ATOM   2689 C  C    . LEU A 1 172 ? -8.91466  -24.06160 25.63978 1.000 14.41361 ? 195 LEU A C    1 
ATOM   2690 O  O    . LEU A 1 172 ? -9.38825  -25.09689 26.11064 1.000 17.14847 ? 195 LEU A O    1 
ATOM   2691 C  CB   . LEU A 1 172 ? -8.64275  -24.37339 23.17330 1.000 14.20727 ? 195 LEU A CB   1 
ATOM   2692 C  CG   . LEU A 1 172 ? -9.02742  -24.00000 21.73983 1.000 15.47670 ? 195 LEU A CG   1 
ATOM   2693 C  CD1  . LEU A 1 172 ? -8.15656  -24.75754 20.74580 1.000 17.37860 ? 195 LEU A CD1  1 
ATOM   2694 C  CD2  . LEU A 1 172 ? -10.49202 -24.30026 21.49254 1.000 16.62931 ? 195 LEU A CD2  1 
ATOM   2695 H  H    . LEU A 1 172 ? -8.35897  -21.92509 24.06353 1.000 15.19238 ? 195 LEU A H    1 
ATOM   2696 H  HA   . LEU A 1 172 ? -10.31429 -23.80635 24.19301 1.000 16.25112 ? 195 LEU A HA   1 
ATOM   2697 H  HB2  . LEU A 1 172 ? -7.68995  -24.21823 23.26816 1.000 17.04872 ? 195 LEU A HB2  1 
ATOM   2698 H  HB3  . LEU A 1 172 ? -8.83862  -25.31617 23.29041 1.000 17.04872 ? 195 LEU A HB3  1 
ATOM   2699 H  HG   . LEU A 1 172 ? -8.88526  -23.04954 21.60821 1.000 18.57204 ? 195 LEU A HG   1 
ATOM   2700 H  HD11 . LEU A 1 172 ? -8.45589  -24.55538 19.84555 1.000 20.85432 ? 195 LEU A HD11 1 
ATOM   2701 H  HD12 . LEU A 1 172 ? -7.23411  -24.47931 20.85797 1.000 20.85432 ? 195 LEU A HD12 1 
ATOM   2702 H  HD13 . LEU A 1 172 ? -8.23804  -25.70907 20.91562 1.000 20.85432 ? 195 LEU A HD13 1 
ATOM   2703 H  HD21 . LEU A 1 172 ? -10.68910 -24.15921 20.55330 1.000 19.95517 ? 195 LEU A HD21 1 
ATOM   2704 H  HD22 . LEU A 1 172 ? -10.67020 -25.22294 21.73298 1.000 19.95517 ? 195 LEU A HD22 1 
ATOM   2705 H  HD23 . LEU A 1 172 ? -11.03241 -23.70635 22.03673 1.000 19.95517 ? 195 LEU A HD23 1 
ATOM   2706 N  N    . GLY A 1 173 ? -8.02771  -23.33352 26.28443 1.000 12.21512 ? 196 GLY A N    1 
ATOM   2707 C  CA   . GLY A 1 173 ? -7.60084  -23.62377 27.63154 1.000 11.42641 ? 196 GLY A CA   1 
ATOM   2708 C  C    . GLY A 1 173 ? -8.42334  -22.85740 28.63568 1.000 11.51981 ? 196 GLY A C    1 
ATOM   2709 O  O    . GLY A 1 173 ? -9.51947  -22.38349 28.34310 1.000 12.81441 ? 196 GLY A O    1 
ATOM   2710 H  H    . GLY A 1 173 ? -7.64516  -22.64028 25.94876 1.000 14.65814 ? 196 GLY A H    1 
ATOM   2711 H  HA2  . GLY A 1 173 ? -7.69875  -24.57259 27.80772 1.000 13.71169 ? 196 GLY A HA2  1 
ATOM   2712 H  HA3  . GLY A 1 173 ? -6.66888  -23.37715 27.73894 1.000 13.71169 ? 196 GLY A HA3  1 
ATOM   2713 N  N    . LYS A 1 174 ? -7.89037  -22.74137 29.84343 1.000 11.92258 ? 197 LYS A N    1 
ATOM   2714 C  CA   . LYS A 1 174 ? -8.62186  -22.16562 30.97755 1.000 13.06609 ? 197 LYS A CA   1 
ATOM   2715 C  C    . LYS A 1 174 ? -7.86786  -21.00585 31.61861 1.000 12.16331 ? 197 LYS A C    1 
ATOM   2716 O  O    . LYS A 1 174 ? -7.94636  -20.76525 32.82725 1.000 13.69441 ? 197 LYS A O    1 
ATOM   2717 C  CB   . LYS A 1 174 ? -9.07608  -23.25329 31.94917 1.000 16.50629 ? 197 LYS A CB   1 
ATOM   2718 C  CG   . LYS A 1 174 ? -9.99565  -24.26612 31.25403 1.000 19.72485 ? 197 LYS A CG   1 
ATOM   2719 C  CD   . LYS A 1 174 ? -10.70667 -25.22517 32.19017 1.000 24.13769 ? 197 LYS A CD   1 
ATOM   2720 C  CE   . LYS A 1 174 ? -11.63724 -26.13347 31.40199 1.000 28.03711 ? 197 LYS A CE   1 
ATOM   2721 N  NZ   . LYS A 1 174 ? -12.30447 -27.11729 32.28692 1.000 31.24608 ? 197 LYS A NZ   1 
ATOM   2722 H  H    . LYS A 1 174 ? -7.09160  -22.99230 30.03990 1.000 14.30709 ? 197 LYS A H    1 
ATOM   2723 H  HA   . LYS A 1 174 ? -9.44025  -21.75806 30.65349 1.000 15.67931 ? 197 LYS A HA   1 
ATOM   2724 H  HB2  . LYS A 1 174 ? -8.30017  -23.72562 32.28941 1.000 19.80755 ? 197 LYS A HB2  1 
ATOM   2725 H  HB3  . LYS A 1 174 ? -9.56474  -22.84688 32.68193 1.000 19.80755 ? 197 LYS A HB3  1 
ATOM   2726 H  HG2  . LYS A 1 174 ? -10.67661 -23.77936 30.76387 1.000 23.66982 ? 197 LYS A HG2  1 
ATOM   2727 H  HG3  . LYS A 1 174 ? -9.46285  -24.79790 30.64228 1.000 23.66982 ? 197 LYS A HG3  1 
ATOM   2728 H  HD2  . LYS A 1 174 ? -10.05412 -25.77460 32.65191 1.000 28.96523 ? 197 LYS A HD2  1 
ATOM   2729 H  HD3  . LYS A 1 174 ? -11.23275 -24.72413 32.83289 1.000 28.96523 ? 197 LYS A HD3  1 
ATOM   2730 H  HE2  . LYS A 1 174 ? -12.32065 -25.59756 30.96996 1.000 33.64454 ? 197 LYS A HE2  1 
ATOM   2731 H  HE3  . LYS A 1 174 ? -11.12567 -26.61863 30.73579 1.000 33.64454 ? 197 LYS A HE3  1 
ATOM   2732 H  HZ1  . LYS A 1 174 ? -12.70764 -27.74218 31.79798 1.000 37.49530 ? 197 LYS A HZ1  1 
ATOM   2733 H  HZ2  . LYS A 1 174 ? -11.70420 -27.50710 32.81590 1.000 37.49530 ? 197 LYS A HZ2  1 
ATOM   2734 H  HZ3  . LYS A 1 174 ? -12.91271 -26.70882 32.79218 1.000 37.49530 ? 197 LYS A HZ3  1 
ATOM   2735 N  N    . ALA A 1 175 ? -7.18232  -20.22231 30.77998 1.000 10.72882 ? 198 ALA A N    1 
ATOM   2736 C  CA   . ALA A 1 175 ? -6.63617  -18.94658 31.24241 1.000 11.69661 ? 198 ALA A CA   1 
ATOM   2737 C  C    . ALA A 1 175 ? -7.73703  -18.03848 31.76527 1.000 10.80713 ? 198 ALA A C    1 
ATOM   2738 O  O    . ALA A 1 175 ? -7.52750  -17.24911 32.70229 1.000 12.30248 ? 198 ALA A O    1 
ATOM   2739 C  CB   . ALA A 1 175 ? -5.91492  -18.22544 30.10811 1.000 13.72288 ? 198 ALA A CB   1 
ATOM   2740 H  H    . ALA A 1 175 ? -7.02293  -20.40346 29.95452 1.000 12.87458 ? 198 ALA A H    1 
ATOM   2741 H  HA   . ALA A 1 175 ? -5.99822  -19.13198 31.94920 1.000 14.03594 ? 198 ALA A HA   1 
ATOM   2742 H  HB1  . ALA A 1 175 ? -5.62287  -17.35542 30.42224 1.000 16.46746 ? 198 ALA A HB1  1 
ATOM   2743 H  HB2  . ALA A 1 175 ? -5.14809  -18.75321 29.83548 1.000 16.46746 ? 198 ALA A HB2  1 
ATOM   2744 H  HB3  . ALA A 1 175 ? -6.52585  -18.11980 29.36212 1.000 16.46746 ? 198 ALA A HB3  1 
ATOM   2745 N  N    . LEU A 1 176 ? -8.90173  -18.11839 31.14356 1.000 10.15249 ? 199 LEU A N    1 
ATOM   2746 C  CA   . LEU A 1 176 ? -10.07636 -17.36803 31.54598 1.000 11.44116 ? 199 LEU A CA   1 
ATOM   2747 C  C    . LEU A 1 176 ? -11.10130 -18.31995 32.13871 1.000 12.24777 ? 199 LEU A C    1 
ATOM   2748 O  O    . LEU A 1 176 ? -11.13688 -19.50981 31.80376 1.000 12.44672 ? 199 LEU A O    1 
ATOM   2749 C  CB   . LEU A 1 176 ? -10.68977 -16.65291 30.33761 1.000 11.56508 ? 199 LEU A CB   1 
ATOM   2750 C  CG   . LEU A 1 176 ? -9.80455  -15.62905 29.61401 1.000 11.16195 ? 199 LEU A CG   1 
ATOM   2751 C  CD1  . LEU A 1 176 ? -10.46607 -15.17445 28.33139 1.000 11.85476 ? 199 LEU A CD1  1 
ATOM   2752 C  CD2  . LEU A 1 176 ? -9.51821  -14.44330 30.53075 1.000 13.35406 ? 199 LEU A CD2  1 
ATOM   2753 H  H    . LEU A 1 176 ? -9.04082  -18.62037 30.45926 1.000 12.18298 ? 199 LEU A H    1 
ATOM   2754 H  HA   . LEU A 1 176 ? -9.83976  -16.70567 32.21395 1.000 13.72940 ? 199 LEU A HA   1 
ATOM   2755 H  HB2  . LEU A 1 176 ? -10.93550 -17.32674 29.68456 1.000 13.87809 ? 199 LEU A HB2  1 
ATOM   2756 H  HB3  . LEU A 1 176 ? -11.48082 -16.17997 30.64005 1.000 13.87809 ? 199 LEU A HB3  1 
ATOM   2757 H  HG   . LEU A 1 176 ? -8.95744  -16.03990 29.38053 1.000 13.39434 ? 199 LEU A HG   1 
ATOM   2758 H  HD11 . LEU A 1 176 ? -9.89598  -14.52130 27.89631 1.000 14.22571 ? 199 LEU A HD11 1 
ATOM   2759 H  HD12 . LEU A 1 176 ? -10.59194 -15.94195 27.75173 1.000 14.22571 ? 199 LEU A HD12 1 
ATOM   2760 H  HD13 . LEU A 1 176 ? -11.32451 -14.77545 28.54301 1.000 14.22571 ? 199 LEU A HD13 1 
ATOM   2761 H  HD21 . LEU A 1 176 ? -8.99886  -13.78514 30.04290 1.000 16.02487 ? 199 LEU A HD21 1 
ATOM   2762 H  HD22 . LEU A 1 176 ? -10.35975 -14.05478 30.81672 1.000 16.02487 ? 199 LEU A HD22 1 
ATOM   2763 H  HD23 . LEU A 1 176 ? -9.01826  -14.75377 31.30182 1.000 16.02487 ? 199 LEU A HD23 1 
ATOM   2764 N  N    . GLY A 1 177 ? -11.92806 -17.78214 33.01476 1.000 13.24795 ? 200 GLY A N    1 
ATOM   2765 C  CA   . GLY A 1 177 ? -13.04123 -18.52031 33.56982 1.000 15.30476 ? 200 GLY A CA   1 
ATOM   2766 C  C    . GLY A 1 177 ? -14.03613 -18.91002 32.49592 1.000 14.69111 ? 200 GLY A C    1 
ATOM   2767 O  O    . GLY A 1 177 ? -14.04168 -18.41074 31.37383 1.000 14.92423 ? 200 GLY A O    1 
ATOM   2768 H  H    . GLY A 1 177 ? -11.86473 -16.97662 33.30925 1.000 15.89754 ? 200 GLY A H    1 
ATOM   2769 H  HA2  . GLY A 1 177 ? -12.71499 -19.32745 33.99760 1.000 18.36571 ? 200 GLY A HA2  1 
ATOM   2770 H  HA3  . GLY A 1 177 ? -13.49608 -17.97460 34.23028 1.000 18.36571 ? 200 GLY A HA3  1 
ATOM   2771 N  N    . ASP A 1 178 ? -14.91910 -19.83752 32.87519 1.000 17.40909 ? 201 ASP A N    1 
ATOM   2772 C  CA   . ASP A 1 178 ? -15.83628 -20.44204 31.91648 1.000 18.18756 ? 201 ASP A CA   1 
ATOM   2773 C  C    . ASP A 1 178 ? -16.64097 -19.37992 31.17692 1.000 16.13062 ? 201 ASP A C    1 
ATOM   2774 O  O    . ASP A 1 178 ? -16.73500 -19.39523 29.94314 1.000 17.75236 ? 201 ASP A O    1 
ATOM   2775 C  CB   . ASP A 1 178 ? -16.73055 -21.41489 32.69732 1.000 25.04824 ? 201 ASP A CB   1 
ATOM   2776 C  CG   . ASP A 1 178 ? -17.76373 -22.08434 31.84659 1.000 31.70443 ? 201 ASP A CG   1 
ATOM   2777 O  OD1  . ASP A 1 178 ? -17.39079 -22.71116 30.83566 1.000 35.82673 ? 201 ASP A OD1  1 
ATOM   2778 O  OD2  . ASP A 1 178 ? -18.95450 -22.00337 32.21023 1.000 33.01747 ? 201 ASP A OD2  1 
ATOM   2779 H  H    . ASP A 1 178 ? -15.00491 -20.13114 33.67895 1.000 20.89090 ? 201 ASP A H    1 
ATOM   2780 H  HA   . ASP A 1 178 ? -15.35661 -20.93567 31.23300 1.000 21.82507 ? 201 ASP A HA   1 
ATOM   2781 H  HB2  . ASP A 1 178 ? -16.17457 -22.10638 33.08929 1.000 30.05789 ? 201 ASP A HB2  1 
ATOM   2782 H  HB3  . ASP A 1 178 ? -17.19232 -20.92495 33.39563 1.000 30.05789 ? 201 ASP A HB3  1 
ATOM   2783 N  N    A SER A 1 179 ? -17.21193 -18.43654 31.90945 0.601 16.24052 ? 202 SER A N    1 
ATOM   2784 N  N    B SER A 1 179 ? -17.25455 -18.45500 31.92614 0.399 16.05737 ? 202 SER A N    1 
ATOM   2785 C  CA   A SER A 1 179 ? -18.01292 -17.41179 31.25725 0.601 15.54131 ? 202 SER A CA   1 
ATOM   2786 C  CA   B SER A 1 179 ? -18.00229 -17.36387 31.30577 0.399 15.50022 ? 202 SER A CA   1 
ATOM   2787 C  C    A SER A 1 179 ? -17.15604 -16.50900 30.37817 0.601 15.20842 ? 202 SER A C    1 
ATOM   2788 C  C    B SER A 1 179 ? -17.12091 -16.57878 30.35178 0.399 15.07905 ? 202 SER A C    1 
ATOM   2789 O  O    A SER A 1 179 ? -17.57841 -16.11406 29.28463 0.601 14.46875 ? 202 SER A O    1 
ATOM   2790 O  O    B SER A 1 179 ? -17.48839 -16.31951 29.19927 0.399 15.15432 ? 202 SER A O    1 
ATOM   2791 C  CB   A SER A 1 179 ? -18.73806 -16.61031 32.32968 0.601 15.58436 ? 202 SER A CB   1 
ATOM   2792 C  CB   B SER A 1 179 ? -18.48959 -16.38805 32.38014 0.399 15.57855 ? 202 SER A CB   1 
ATOM   2793 O  OG   A SER A 1 179 ? -19.53036 -15.63749 31.72650 0.601 13.75646 ? 202 SER A OG   1 
ATOM   2794 O  OG   B SER A 1 179 ? -19.63544 -16.84330 33.05226 0.399 14.33859 ? 202 SER A OG   1 
ATOM   2795 H  H    A SER A 1 179 ? -17.15382 -18.36723 32.76468 0.601 19.48863 ? 202 SER A H    1 
ATOM   2796 H  H    B SER A 1 179 ? -17.25144 -18.43939 32.78599 0.399 19.26884 ? 202 SER A H    1 
ATOM   2797 H  HA   A SER A 1 179 ? -18.67184 -17.82592 30.67826 0.601 18.64958 ? 202 SER A HA   1 
ATOM   2798 H  HA   B SER A 1 179 ? -18.75569 -17.75038 30.83259 0.399 18.60027 ? 202 SER A HA   1 
ATOM   2799 H  HB2  A SER A 1 179 ? -19.30041 -17.20524 32.84999 0.601 18.70123 ? 202 SER A HB2  1 
ATOM   2800 H  HB2  B SER A 1 179 ? -17.77977 -16.26659 33.02999 0.399 18.69426 ? 202 SER A HB2  1 
ATOM   2801 H  HB3  A SER A 1 179 ? -18.08616 -16.18158 32.90599 0.601 18.70123 ? 202 SER A HB3  1 
ATOM   2802 H  HB3  B SER A 1 179 ? -18.69844 -15.54163 31.95486 0.399 18.69426 ? 202 SER A HB3  1 
ATOM   2803 H  HG   A SER A 1 179 ? -19.05013 -15.00503 31.45268 0.601 16.50776 ? 202 SER A HG   1 
ATOM   2804 H  HG   B SER A 1 179 ? -19.65756 -17.68298 33.04605 0.399 17.20631 ? 202 SER A HG   1 
ATOM   2805 N  N    . GLN A 1 180 ? -15.95692 -16.17125 30.83866 1.000 14.34677 ? 203 GLN A N    1 
ATOM   2806 C  CA   . GLN A 1 180 ? -15.13193 -15.22393 30.10456 1.000 13.63188 ? 203 GLN A CA   1 
ATOM   2807 C  C    . GLN A 1 180 ? -14.56992 -15.85324 28.84051 1.000 12.74030 ? 203 GLN A C    1 
ATOM   2808 O  O    . GLN A 1 180 ? -14.49186 -15.19351 27.79654 1.000 12.86918 ? 203 GLN A O    1 
ATOM   2809 C  CB   . GLN A 1 180 ? -14.01404 -14.72038 31.01882 1.000 13.74158 ? 203 GLN A CB   1 
ATOM   2810 C  CG   . GLN A 1 180 ? -14.49281 -13.83467 32.15959 1.000 14.53899 ? 203 GLN A CG   1 
ATOM   2811 C  CD   . GLN A 1 180 ? -15.16141 -14.59597 33.30182 1.000 16.78864 ? 203 GLN A CD   1 
ATOM   2812 O  OE1  . GLN A 1 180 ? -14.92738 -15.78396 33.49722 1.000 17.31687 ? 203 GLN A OE1  1 
ATOM   2813 N  NE2  . GLN A 1 180 ? -16.00464 -13.90341 34.05007 1.000 19.26354 ? 203 GLN A NE2  1 
ATOM   2814 H  H    . GLN A 1 180 ? -15.60609 -16.47372 31.56324 1.000 17.21612 ? 203 GLN A H    1 
ATOM   2815 H  HA   . GLN A 1 180 ? -15.66769 -14.46179 29.83437 1.000 16.35825 ? 203 GLN A HA   1 
ATOM   2816 H  HB2  . GLN A 1 180 ? -13.56442 -15.48598 31.40945 1.000 16.48989 ? 203 GLN A HB2  1 
ATOM   2817 H  HB3  . GLN A 1 180 ? -13.38823 -14.20352 30.48768 1.000 16.48989 ? 203 GLN A HB3  1 
ATOM   2818 H  HG2  . GLN A 1 180 ? -13.72976 -13.36236 32.52779 1.000 17.44678 ? 203 GLN A HG2  1 
ATOM   2819 H  HG3  . GLN A 1 180 ? -15.13875 -13.20060 31.81086 1.000 17.44678 ? 203 GLN A HG3  1 
ATOM   2820 H  HE21 . GLN A 1 180 ? -16.14861 -13.07289 33.87946 1.000 23.11624 ? 203 GLN A HE21 1 
ATOM   2821 H  HE22 . GLN A 1 180 ? -16.40876 -14.28377 34.70705 1.000 23.11624 ? 203 GLN A HE22 1 
ATOM   2822 N  N    . ARG A 1 181 ? -14.14371 -17.11022 28.92317 1.000 13.52051 ? 204 ARG A N    1 
ATOM   2823 C  CA   A ARG A 1 181 ? -13.65339 -17.79107 27.73007 0.623 14.21868 ? 204 ARG A CA   1 
ATOM   2824 C  CA   B ARG A 1 181 ? -13.65295 -17.78566 27.72942 0.377 14.23222 ? 204 ARG A CA   1 
ATOM   2825 C  C    . ARG A 1 181 ? -14.75410 -17.91010 26.68716 1.000 14.27394 ? 204 ARG A C    1 
ATOM   2826 O  O    . ARG A 1 181 ? -14.51784 -17.69297 25.48925 1.000 14.19498 ? 204 ARG A O    1 
ATOM   2827 C  CB   A ARG A 1 181 ? -13.12324 -19.18037 28.09265 0.623 16.95841 ? 204 ARG A CB   1 
ATOM   2828 C  CB   B ARG A 1 181 ? -13.11251 -19.16532 28.09733 0.377 16.15297 ? 204 ARG A CB   1 
ATOM   2829 C  CG   A ARG A 1 181 ? -12.81897 -20.04994 26.88815 0.623 19.85780 ? 204 ARG A CG   1 
ATOM   2830 C  CG   B ARG A 1 181 ? -12.84989 -20.04491 26.90386 0.377 18.27433 ? 204 ARG A CG   1 
ATOM   2831 C  CD   A ARG A 1 181 ? -12.36262 -21.43911 27.28270 0.623 21.16730 ? 204 ARG A CD   1 
ATOM   2832 C  CD   B ARG A 1 181 ? -12.12002 -21.30247 27.30809 0.377 19.77843 ? 204 ARG A CD   1 
ATOM   2833 N  NE   A ARG A 1 181 ? -13.45895 -22.30178 27.70403 0.623 22.58400 ? 204 ARG A NE   1 
ATOM   2834 N  NE   B ARG A 1 181 ? -12.91835 -22.17378 28.16186 0.377 21.01962 ? 204 ARG A NE   1 
ATOM   2835 C  CZ   A ARG A 1 181 ? -13.31470 -23.58309 28.01693 0.623 23.21767 ? 204 ARG A CZ   1 
ATOM   2836 C  CZ   B ARG A 1 181 ? -12.86139 -22.20467 29.48714 0.377 21.91355 ? 204 ARG A CZ   1 
ATOM   2837 N  NH1  A ARG A 1 181 ? -12.13582 -24.17950 27.95049 0.623 24.26175 ? 204 ARG A NH1  1 
ATOM   2838 N  NH1  B ARG A 1 181 ? -12.11444 -21.35385 30.16941 0.377 20.20467 ? 204 ARG A NH1  1 
ATOM   2839 N  NH2  A ARG A 1 181 ? -14.37868 -24.28321 28.40068 0.623 23.29521 ? 204 ARG A NH2  1 
ATOM   2840 N  NH2  B ARG A 1 181 ? -13.56362 -23.12390 30.14510 0.377 23.10944 ? 204 ARG A NH2  1 
ATOM   2841 H  H    A ARG A 1 181 ? -14.12806 -17.58172 29.64223 0.623 16.22462 ? 204 ARG A H    1 
ATOM   2842 H  H    B ARG A 1 181 ? -14.12869 -17.58295 29.64144 0.377 16.22462 ? 204 ARG A H    1 
ATOM   2843 H  HA   A ARG A 1 181 ? -12.92125 -17.27680 27.35539 0.623 17.06241 ? 204 ARG A HA   1 
ATOM   2844 H  HA   B ARG A 1 181 ? -12.92666 -17.26799 27.34808 0.377 17.07867 ? 204 ARG A HA   1 
ATOM   2845 H  HB2  A ARG A 1 181 ? -12.30259 -19.07866 28.59970 0.623 20.35009 ? 204 ARG A HB2  1 
ATOM   2846 H  HB2  B ARG A 1 181 ? -12.27592 -19.05613 28.57597 0.377 19.38356 ? 204 ARG A HB2  1 
ATOM   2847 H  HB3  A ARG A 1 181 ? -13.78956 -19.63861 28.62832 0.623 20.35009 ? 204 ARG A HB3  1 
ATOM   2848 H  HB3  B ARG A 1 181 ? -13.76106 -19.61517 28.66118 0.377 19.38356 ? 204 ARG A HB3  1 
ATOM   2849 H  HG2  A ARG A 1 181 ? -13.62020 -20.13776 26.34850 0.623 23.82936 ? 204 ARG A HG2  1 
ATOM   2850 H  HG2  B ARG A 1 181 ? -13.69332 -20.29714 26.49654 0.377 21.92919 ? 204 ARG A HG2  1 
ATOM   2851 H  HG3  A ARG A 1 181 ? -12.11217 -19.63688 26.36784 0.623 23.82936 ? 204 ARG A HG3  1 
ATOM   2852 H  HG3  B ARG A 1 181 ? -12.30237 -19.56493 26.26297 0.377 21.92919 ? 204 ARG A HG3  1 
ATOM   2853 H  HD2  A ARG A 1 181 ? -11.92980 -21.85666 26.52164 0.623 25.40076 ? 204 ARG A HD2  1 
ATOM   2854 H  HD2  B ARG A 1 181 ? -11.88398 -21.80066 26.50998 0.377 23.73412 ? 204 ARG A HD2  1 
ATOM   2855 H  HD3  A ARG A 1 181 ? -11.73814 -21.36770 28.02150 0.623 25.40076 ? 204 ARG A HD3  1 
ATOM   2856 H  HD3  B ARG A 1 181 ? -11.31807 -21.05873 27.79633 0.377 23.73412 ? 204 ARG A HD3  1 
ATOM   2857 H  HE   A ARG A 1 181 ? -14.24657 -21.95992 27.75279 0.623 27.10081 ? 204 ARG A HE   1 
ATOM   2858 H  HE   B ARG A 1 181 ? -13.46940 -22.70977 27.77629 0.377 25.22355 ? 204 ARG A HE   1 
ATOM   2859 H  HH11 A ARG A 1 181 ? -11.44290 -23.73573 27.70041 0.623 29.11410 ? 204 ARG A HH11 1 
ATOM   2860 H  HH11 B ARG A 1 181 ? -11.64956 -20.76116 29.75443 0.377 24.24561 ? 204 ARG A HH11 1 
ATOM   2861 H  HH12 A ARG A 1 181 ? -12.06232 -25.01100 28.15737 0.623 29.11410 ? 204 ARG A HH12 1 
ATOM   2862 H  HH12 B ARG A 1 181 ? -12.09336 -21.39299 31.02826 0.377 24.24561 ? 204 ARG A HH12 1 
ATOM   2863 H  HH21 A ARG A 1 181 ? -15.14972 -23.90476 28.44389 0.623 27.95425 ? 204 ARG A HH21 1 
ATOM   2864 H  HH21 B ARG A 1 181 ? -14.04642 -23.68811 29.71130 0.377 27.73133 ? 204 ARG A HH21 1 
ATOM   2865 H  HH22 A ARG A 1 181 ? -14.29551 -25.11430 28.60556 0.623 27.95425 ? 204 ARG A HH22 1 
ATOM   2866 H  HH22 B ARG A 1 181 ? -13.53463 -23.15374 31.00410 0.377 27.73133 ? 204 ARG A HH22 1 
ATOM   2867 N  N    . ALA A 1 182 ? -15.95313 -18.29169 27.11969 1.000 14.55765 ? 205 ALA A N    1 
ATOM   2868 C  CA   . ALA A 1 182 ? -17.06320 -18.38924 26.18754 1.000 15.27049 ? 205 ALA A CA   1 
ATOM   2869 C  C    . ALA A 1 182 ? -17.34207 -17.04296 25.54457 1.000 13.92508 ? 205 ALA A C    1 
ATOM   2870 O  O    . ALA A 1 182 ? -17.62528 -16.96387 24.33922 1.000 15.20918 ? 205 ALA A O    1 
ATOM   2871 C  CB   . ALA A 1 182 ? -18.30934 -18.90141 26.90397 1.000 15.80278 ? 205 ALA A CB   1 
ATOM   2872 H  H    . ALA A 1 182 ? -16.14421 -18.49536 27.93308 1.000 17.46918 ? 205 ALA A H    1 
ATOM   2873 H  HA   . ALA A 1 182 ? -16.83592 -19.02514 25.49120 1.000 18.32459 ? 205 ALA A HA   1 
ATOM   2874 H  HB1  . ALA A 1 182 ? -19.04045 -18.95235 26.26852 1.000 18.96334 ? 205 ALA A HB1  1 
ATOM   2875 H  HB2  . ALA A 1 182 ? -18.12522 -19.78162 27.26761 1.000 18.96334 ? 205 ALA A HB2  1 
ATOM   2876 H  HB3  . ALA A 1 182 ? -18.53606 -18.28826 27.62059 1.000 18.96334 ? 205 ALA A HB3  1 
ATOM   2877 N  N    . GLN A 1 183 ? -17.23112 -15.96738 26.32388 1.000 13.77496 ? 206 GLN A N    1 
ATOM   2878 C  CA   . GLN A 1 183 ? -17.49033 -14.63929 25.79294 1.000 12.52619 ? 206 GLN A CA   1 
ATOM   2879 C  C    . GLN A 1 183 ? -16.44337 -14.25005 24.74804 1.000 13.08106 ? 206 GLN A C    1 
ATOM   2880 O  O    . GLN A 1 183 ? -16.77686 -13.65951 23.70991 1.000 13.28994 ? 206 GLN A O    1 
ATOM   2881 C  CB   . GLN A 1 183 ? -17.52222 -13.62336 26.93374 1.000 13.65781 ? 206 GLN A CB   1 
ATOM   2882 C  CG   . GLN A 1 183 ? -17.84173 -12.23255 26.44610 1.000 13.81636 ? 206 GLN A CG   1 
ATOM   2883 C  CD   . GLN A 1 183 ? -19.23605 -12.12689 25.86282 1.000 15.55327 ? 206 GLN A CD   1 
ATOM   2884 O  OE1  . GLN A 1 183 ? -20.21087 -11.96284 26.60062 1.000 18.35858 ? 206 GLN A OE1  1 
ATOM   2885 N  NE2  . GLN A 1 183 ? -19.34819 -12.25067 24.54335 1.000 15.85796 ? 206 GLN A NE2  1 
ATOM   2886 H  H    . GLN A 1 183 ? -17.00933 -15.98266 27.15464 1.000 16.52995 ? 206 GLN A H    1 
ATOM   2887 H  HA   . GLN A 1 183 ? -18.35895 -14.63303 25.36125 1.000 15.03142 ? 206 GLN A HA   1 
ATOM   2888 H  HB2  . GLN A 1 183 ? -18.20327 -13.88432 27.57326 1.000 16.38937 ? 206 GLN A HB2  1 
ATOM   2889 H  HB3  . GLN A 1 183 ? -16.65347 -13.60142 27.36465 1.000 16.38937 ? 206 GLN A HB3  1 
ATOM   2890 H  HG2  . GLN A 1 183 ? -17.77944 -11.61373 27.19047 1.000 16.57963 ? 206 GLN A HG2  1 
ATOM   2891 H  HG3  . GLN A 1 183 ? -17.20723 -11.98547 25.75527 1.000 16.57963 ? 206 GLN A HG3  1 
ATOM   2892 H  HE21 . GLN A 1 183 ? -18.64752 -12.38417 24.06290 1.000 19.02955 ? 206 GLN A HE21 1 
ATOM   2893 H  HE22 . GLN A 1 183 ? -20.12137 -12.19720 24.17061 1.000 19.02955 ? 206 GLN A HE22 1 
ATOM   2894 N  N    . LEU A 1 184 ? -15.16614 -14.53357 25.01720 1.000 11.97024 ? 207 LEU A N    1 
ATOM   2895 C  CA   . LEU A 1 184 ? -14.13245 -14.21799 24.03581 1.000 11.52265 ? 207 LEU A CA   1 
ATOM   2896 C  C    . LEU A 1 184 ? -14.39241 -14.95207 22.72790 1.000 11.84567 ? 207 LEU A C    1 
ATOM   2897 O  O    . LEU A 1 184 ? -14.29735 -14.37658 21.63687 1.000 12.94406 ? 207 LEU A O    1 
ATOM   2898 C  CB   . LEU A 1 184 ? -12.75632 -14.58532 24.59823 1.000 11.21639 ? 207 LEU A CB   1 
ATOM   2899 C  CG   . LEU A 1 184 ? -11.58775 -14.33790 23.64406 1.000 10.75983 ? 207 LEU A CG   1 
ATOM   2900 C  CD1  . LEU A 1 184 ? -11.48876 -12.87918 23.26814 1.000 11.60522 ? 207 LEU A CD1  1 
ATOM   2901 C  CD2  . LEU A 1 184 ? -10.28282 -14.83192 24.23137 1.000 11.13028 ? 207 LEU A CD2  1 
ATOM   2902 H  H    . LEU A 1 184 ? -14.88127 -14.89884 25.74179 1.000 14.36428 ? 207 LEU A H    1 
ATOM   2903 H  HA   . LEU A 1 184 ? -14.14064 -13.26472 23.85658 1.000 13.82718 ? 207 LEU A HA   1 
ATOM   2904 H  HB2  . LEU A 1 184 ? -12.59940 -14.05659 25.39617 1.000 13.45966 ? 207 LEU A HB2  1 
ATOM   2905 H  HB3  . LEU A 1 184 ? -12.75739 -15.52945 24.82075 1.000 13.45966 ? 207 LEU A HB3  1 
ATOM   2906 H  HG   . LEU A 1 184 ? -11.75191 -14.84121 22.83127 1.000 12.91180 ? 207 LEU A HG   1 
ATOM   2907 H  HD11 . LEU A 1 184 ? -10.69646 -12.74621 22.72456 1.000 13.92627 ? 207 LEU A HD11 1 
ATOM   2908 H  HD12 . LEU A 1 184 ? -12.28005 -12.62794 22.76650 1.000 13.92627 ? 207 LEU A HD12 1 
ATOM   2909 H  HD13 . LEU A 1 184 ? -11.42765 -12.34794 24.07743 1.000 13.92627 ? 207 LEU A HD13 1 
ATOM   2910 H  HD21 . LEU A 1 184 ? -9.57984  -14.72762 23.57118 1.000 13.35634 ? 207 LEU A HD21 1 
ATOM   2911 H  HD22 . LEU A 1 184 ? -10.07446 -14.30966 25.02176 1.000 13.35634 ? 207 LEU A HD22 1 
ATOM   2912 H  HD23 . LEU A 1 184 ? -10.37752 -15.76766 24.46870 1.000 13.35634 ? 207 LEU A HD23 1 
ATOM   2913 N  N    . VAL A 1 185 ? -14.69893 -16.24375 22.82411 1.000 12.98132 ? 208 VAL A N    1 
ATOM   2914 C  CA   . VAL A 1 185 ? -14.91535 -17.03831 21.62573 1.000 14.48949 ? 208 VAL A CA   1 
ATOM   2915 C  C    . VAL A 1 185 ? -16.12746 -16.52571 20.86881 1.000 15.28773 ? 208 VAL A C    1 
ATOM   2916 O  O    . VAL A 1 185 ? -16.10527 -16.40539 19.64086 1.000 15.62561 ? 208 VAL A O    1 
ATOM   2917 C  CB   . VAL A 1 185 ? -15.05755 -18.52361 22.00128 1.000 16.36158 ? 208 VAL A CB   1 
ATOM   2918 C  CG1  . VAL A 1 185 ? -15.59427 -19.32385 20.81955 1.000 19.06665 ? 208 VAL A CG1  1 
ATOM   2919 C  CG2  . VAL A 1 185 ? -13.70901 -19.06251 22.48004 1.000 17.90934 ? 208 VAL A CG2  1 
ATOM   2920 H  H    . VAL A 1 185 ? -14.78588 -16.67606 23.56245 1.000 15.57758 ? 208 VAL A H    1 
ATOM   2921 H  HA   . VAL A 1 185 ? -14.14490 -16.94993 21.04307 1.000 17.38739 ? 208 VAL A HA   1 
ATOM   2922 H  HB   . VAL A 1 185 ? -15.69527 -18.62053 22.72572 1.000 19.63390 ? 208 VAL A HB   1 
ATOM   2923 H  HG11 . VAL A 1 185 ? -15.43884 -20.26767 20.98061 1.000 22.87998 ? 208 VAL A HG11 1 
ATOM   2924 H  HG12 . VAL A 1 185 ? -16.54542 -19.15578 20.73025 1.000 22.87998 ? 208 VAL A HG12 1 
ATOM   2925 H  HG13 . VAL A 1 185 ? -15.13205 -19.04532 20.01352 1.000 22.87998 ? 208 VAL A HG13 1 
ATOM   2926 H  HG21 . VAL A 1 185 ? -13.82069 -19.98191 22.76838 1.000 21.49121 ? 208 VAL A HG21 1 
ATOM   2927 H  HG22 . VAL A 1 185 ? -13.07411 -19.02026 21.74790 1.000 21.49121 ? 208 VAL A HG22 1 
ATOM   2928 H  HG23 . VAL A 1 185 ? -13.39669 -18.51926 23.22047 1.000 21.49121 ? 208 VAL A HG23 1 
ATOM   2929 N  N    . THR A 1 186 ? -17.21669 -16.24846 21.58265 1.000 15.37028 ? 209 THR A N    1 
ATOM   2930 C  CA   . THR A 1 186 ? -18.40381 -15.72809 20.91754 1.000 16.02789 ? 209 THR A CA   1 
ATOM   2931 C  C    . THR A 1 186 ? -18.07645 -14.43761 20.18630 1.000 14.94870 ? 209 THR A C    1 
ATOM   2932 O  O    . THR A 1 186 ? -18.51510 -14.23569 19.04311 1.000 15.78011 ? 209 THR A O    1 
ATOM   2933 C  CB   . THR A 1 186 ? -19.50043 -15.49381 21.95842 1.000 18.16750 ? 209 THR A CB   1 
ATOM   2934 O  OG1  . THR A 1 186 ? -19.90923 -16.75970 22.49410 1.000 20.69041 ? 209 THR A OG1  1 
ATOM   2935 C  CG2  . THR A 1 186 ? -20.69668 -14.76846 21.35839 1.000 19.42952 ? 209 THR A CG2  1 
ATOM   2936 H  H    . THR A 1 186 ? -17.29152 -16.35061 22.43328 1.000 18.44433 ? 209 THR A H    1 
ATOM   2937 H  HA   . THR A 1 186 ? -18.73022 -16.37162 20.26929 1.000 19.23347 ? 209 THR A HA   1 
ATOM   2938 H  HB   . THR A 1 186 ? -19.15737 -14.93076 22.66988 1.000 21.80100 ? 209 THR A HB   1 
ATOM   2939 H  HG1  . THR A 1 186 ? -20.36042 -16.64368 23.19308 1.000 24.82850 ? 209 THR A HG1  1 
ATOM   2940 H  HG21 . THR A 1 186 ? -21.42124 -14.73443 22.00240 1.000 23.31542 ? 209 THR A HG21 1 
ATOM   2941 H  HG22 . THR A 1 186 ? -20.44809 -13.86271 21.11607 1.000 23.31542 ? 209 THR A HG22 1 
ATOM   2942 H  HG23 . THR A 1 186 ? -21.00284 -15.23399 20.56438 1.000 23.31542 ? 209 THR A HG23 1 
ATOM   2943 N  N    . TRP A 1 187 ? -17.33280 -13.54149 20.83605 1.000 13.80029 ? 210 TRP A N    1 
ATOM   2944 C  CA   . TRP A 1 187 ? -16.97605 -12.29173 20.18404 1.000 12.54874 ? 210 TRP A CA   1 
ATOM   2945 C  C    . TRP A 1 187 ? -16.15843 -12.55184 18.92125 1.000 13.20321 ? 210 TRP A C    1 
ATOM   2946 O  O    . TRP A 1 187 ? -16.42578 -11.96733 17.86924 1.000 14.14437 ? 210 TRP A O    1 
ATOM   2947 C  CB   . TRP A 1 187 ? -16.21096 -11.37259 21.13865 1.000 12.84531 ? 210 TRP A CB   1 
ATOM   2948 C  CG   . TRP A 1 187 ? -17.05932 -10.59473 22.11143 1.000 14.09504 ? 210 TRP A CG   1 
ATOM   2949 C  CD1  . TRP A 1 187 ? -18.35109 -10.18165 21.94041 1.000 15.53251 ? 210 TRP A CD1  1 
ATOM   2950 C  CD2  . TRP A 1 187 ? -16.66257 -10.11867 23.41298 1.000 13.57100 ? 210 TRP A CD2  1 
ATOM   2951 N  NE1  . TRP A 1 187 ? -18.77700 -9.47984  23.03761 1.000 15.02415 ? 210 TRP A NE1  1 
ATOM   2952 C  CE2  . TRP A 1 187 ? -17.76709 -9.43403  23.95830 1.000 14.81163 ? 210 TRP A CE2  1 
ATOM   2953 C  CE3  . TRP A 1 187 ? -15.49042 -10.21028 24.16936 1.000 13.64853 ? 210 TRP A CE3  1 
ATOM   2954 C  CZ2  . TRP A 1 187 ? -17.73804 -8.85324  25.22355 1.000 14.57290 ? 210 TRP A CZ2  1 
ATOM   2955 C  CZ3  . TRP A 1 187 ? -15.46581 -9.62350  25.42871 1.000 14.57156 ? 210 TRP A CZ3  1 
ATOM   2956 C  CH2  . TRP A 1 187 ? -16.58123 -8.95577  25.93890 1.000 15.57648 ? 210 TRP A CH2  1 
ATOM   2957 H  H    . TRP A 1 187 ? -17.03089 -13.63384 21.63600 1.000 16.56035 ? 210 TRP A H    1 
ATOM   2958 H  HA   . TRP A 1 187 ? -17.79345 -11.83221 19.93586 1.000 15.05849 ? 210 TRP A HA   1 
ATOM   2959 H  HB2  . TRP A 1 187 ? -15.59903 -11.91554 21.65985 1.000 15.41437 ? 210 TRP A HB2  1 
ATOM   2960 H  HB3  . TRP A 1 187 ? -15.71479 -10.72847 20.60967 1.000 15.41437 ? 210 TRP A HB3  1 
ATOM   2961 H  HD1  . TRP A 1 187 ? -18.86770 -10.35268 21.18624 1.000 18.63901 ? 210 TRP A HD1  1 
ATOM   2962 H  HE1  . TRP A 1 187 ? -19.55473 -9.12512  23.13200 1.000 18.02898 ? 210 TRP A HE1  1 
ATOM   2963 H  HE3  . TRP A 1 187 ? -14.74374 -10.65406 23.83706 1.000 16.37823 ? 210 TRP A HE3  1 
ATOM   2964 H  HZ2  . TRP A 1 187 ? -18.48033 -8.41155  25.56825 1.000 17.48748 ? 210 TRP A HZ2  1 
ATOM   2965 H  HZ3  . TRP A 1 187 ? -14.69182 -9.67646  25.94157 1.000 17.48588 ? 210 TRP A HZ3  1 
ATOM   2966 H  HH2  . TRP A 1 187 ? -16.53425 -8.57259  26.78499 1.000 18.69178 ? 210 TRP A HH2  1 
ATOM   2967 N  N    . MET A 1 188 ? -15.16351 -13.43404 18.99772 1.000 13.18006 ? 211 MET A N    1 
ATOM   2968 C  CA   . MET A 1 188 ? -14.30443 -13.66473 17.84255 1.000 12.23083 ? 211 MET A CA   1 
ATOM   2969 C  C    . MET A 1 188 ? -15.06040 -14.35816 16.71183 1.000 14.20823 ? 211 MET A C    1 
ATOM   2970 O  O    . MET A 1 188 ? -14.78265 -14.10409 15.53254 1.000 14.79728 ? 211 MET A O    1 
ATOM   2971 C  CB   . MET A 1 188 ? -13.08706 -14.47800 18.26167 1.000 11.87903 ? 211 MET A CB   1 
ATOM   2972 C  CG   . MET A 1 188 ? -12.13318 -13.70342 19.16752 1.000 10.98975 ? 211 MET A CG   1 
ATOM   2973 S  SD   . MET A 1 188 ? -10.63768 -14.61470 19.57537 1.000 10.86004 ? 211 MET A SD   1 
ATOM   2974 C  CE   . MET A 1 188 ? -9.81711  -14.58465 17.98490 1.000 10.95586 ? 211 MET A CE   1 
ATOM   2975 H  H    . MET A 1 188 ? -14.96929 -13.90195 19.69266 1.000 15.81607 ? 211 MET A H    1 
ATOM   2976 H  HA   . MET A 1 188 ? -13.98472 -12.81062 17.51213 1.000 14.67700 ? 211 MET A HA   1 
ATOM   2977 H  HB2  . MET A 1 188 ? -13.38543 -15.26461 18.74450 1.000 14.25483 ? 211 MET A HB2  1 
ATOM   2978 H  HB3  . MET A 1 188 ? -12.59685 -14.74231 17.46748 1.000 14.25483 ? 211 MET A HB3  1 
ATOM   2979 H  HG2  . MET A 1 188 ? -11.86944 -12.88505 18.71851 1.000 13.18770 ? 211 MET A HG2  1 
ATOM   2980 H  HG3  . MET A 1 188 ? -12.58943 -13.49420 19.99756 1.000 13.18770 ? 211 MET A HG3  1 
ATOM   2981 H  HE1  . MET A 1 188 ? -8.91873  -14.93609 18.08636 1.000 13.14703 ? 211 MET A HE1  1 
ATOM   2982 H  HE2  . MET A 1 188 ? -10.31811 -15.13259 17.36067 1.000 13.14703 ? 211 MET A HE2  1 
ATOM   2983 H  HE3  . MET A 1 188 ? -9.78018  -13.66937 17.66585 1.000 13.14703 ? 211 MET A HE3  1 
ATOM   2984 N  N    . LYS A 1 189 ? -16.02067 -15.23082 17.03713 1.000 15.42645 ? 212 LYS A N    1 
ATOM   2985 C  CA   . LYS A 1 189 ? -16.84275 -15.86098 16.00835 1.000 16.17311 ? 212 LYS A CA   1 
ATOM   2986 C  C    . LYS A 1 189 ? -17.73450 -14.85609 15.29880 1.000 16.87348 ? 212 LYS A C    1 
ATOM   2987 O  O    . LYS A 1 189 ? -18.15077 -15.10604 14.16168 1.000 18.93214 ? 212 LYS A O    1 
ATOM   2988 C  CB   . LYS A 1 189 ? -17.69297 -16.96980 16.62224 1.000 18.09738 ? 212 LYS A CB   1 
ATOM   2989 C  CG   . LYS A 1 189 ? -16.91856 -18.24461 16.91293 1.000 21.06916 ? 212 LYS A CG   1 
ATOM   2990 C  CD   . LYS A 1 189 ? -17.69206 -19.20922 17.81812 1.000 24.94480 ? 212 LYS A CD   1 
ATOM   2991 C  CE   . LYS A 1 189 ? -18.98029 -19.71560 17.20834 1.000 29.30519 ? 212 LYS A CE   1 
ATOM   2992 N  NZ   . LYS A 1 189 ? -19.69893 -20.53519 18.23479 1.000 31.15618 ? 212 LYS A NZ   1 
ATOM   2993 H  H    . LYS A 1 189 ? -16.21225 -15.47096 17.84039 1.000 18.51174 ? 212 LYS A H    1 
ATOM   2994 H  HA   . LYS A 1 189 ? -16.26090 -16.26638 15.34654 1.000 19.40773 ? 212 LYS A HA   1 
ATOM   2995 H  HB2  . LYS A 1 189 ? -18.06381 -16.65094 17.45992 1.000 21.71686 ? 212 LYS A HB2  1 
ATOM   2996 H  HB3  . LYS A 1 189 ? -18.40833 -17.19178 16.00589 1.000 21.71686 ? 212 LYS A HB3  1 
ATOM   2997 H  HG2  . LYS A 1 189 ? -16.73302 -18.70062 16.07715 1.000 25.28299 ? 212 LYS A HG2  1 
ATOM   2998 H  HG3  . LYS A 1 189 ? -16.08743 -18.01639 17.35795 1.000 25.28299 ? 212 LYS A HG3  1 
ATOM   2999 H  HD2  . LYS A 1 189 ? -17.13200 -19.97850 18.00636 1.000 29.93376 ? 212 LYS A HD2  1 
ATOM   3000 H  HD3  . LYS A 1 189 ? -17.91587 -18.75182 18.64371 1.000 29.93376 ? 212 LYS A HD3  1 
ATOM   3001 H  HE2  . LYS A 1 189 ? -19.54159 -18.96852 16.94809 1.000 35.16622 ? 212 LYS A HE2  1 
ATOM   3002 H  HE3  . LYS A 1 189 ? -18.78760 -20.27048 16.43641 1.000 35.16622 ? 212 LYS A HE3  1 
ATOM   3003 H  HZ1  . LYS A 1 189 ? -20.45887 -20.85026 17.89519 1.000 37.38742 ? 212 LYS A HZ1  1 
ATOM   3004 H  HZ2  . LYS A 1 189 ? -19.19006 -21.21993 18.48833 1.000 37.38742 ? 212 LYS A HZ2  1 
ATOM   3005 H  HZ3  . LYS A 1 189 ? -19.88616 -20.03525 18.94690 1.000 37.38742 ? 212 LYS A HZ3  1 
ATOM   3006 N  N    . GLY A 1 190 ? -18.04062 -13.73854 15.94185 1.000 17.39673 ? 213 GLY A N    1 
ATOM   3007 C  CA   . GLY A 1 190 ? -18.84086 -12.68896 15.35573 1.000 17.97594 ? 213 GLY A CA   1 
ATOM   3008 C  C    . GLY A 1 190 ? -18.04748 -11.60161 14.67239 1.000 18.06151 ? 213 GLY A C    1 
ATOM   3009 O  O    . GLY A 1 190 ? -18.61512 -10.56654 14.31273 1.000 20.77311 ? 213 GLY A O    1 
ATOM   3010 H  H    . GLY A 1 190 ? -17.78543 -13.56481 16.74453 1.000 20.87608 ? 213 GLY A H    1 
ATOM   3011 H  HA2  . GLY A 1 190 ? -19.43552 -13.08121 14.69738 1.000 21.57113 ? 213 GLY A HA2  1 
ATOM   3012 H  HA3  . GLY A 1 190 ? -19.37185 -12.27507 16.05405 1.000 21.57113 ? 213 GLY A HA3  1 
ATOM   3013 N  N    . ASN A 1 191 ? -16.74681 -11.78958 14.50674 1.000 16.83314 ? 214 ASN A N    1 
ATOM   3014 C  CA   . ASN A 1 191 ? -15.92983 -10.82782 13.78426 1.000 17.11036 ? 214 ASN A CA   1 
ATOM   3015 C  C    . ASN A 1 191 ? -16.50007 -10.58226 12.39214 1.000 17.51831 ? 214 ASN A C    1 
ATOM   3016 O  O    . ASN A 1 191 ? -16.89102 -11.51361 11.68422 1.000 18.72887 ? 214 ASN A O    1 
ATOM   3017 C  CB   . ASN A 1 191 ? -14.51093 -11.37551 13.66475 1.000 17.40465 ? 214 ASN A CB   1 
ATOM   3018 C  CG   . ASN A 1 191 ? -13.58992 -10.44042 12.93728 1.000 18.09361 ? 214 ASN A CG   1 
ATOM   3019 O  OD1  . ASN A 1 191 ? -13.75058 -9.22723  13.01152 1.000 19.61382 ? 214 ASN A OD1  1 
ATOM   3020 N  ND2  . ASN A 1 191 ? -12.64335 -11.00000 12.18589 1.000 18.78714 ? 214 ASN A ND2  1 
ATOM   3021 H  H    . ASN A 1 191 ? -16.31039 -12.46846 14.80383 1.000 20.19977 ? 214 ASN A H    1 
ATOM   3022 H  HA   . ASN A 1 191 ? -15.91237 -9.98278  14.26019 1.000 20.53244 ? 214 ASN A HA   1 
ATOM   3023 H  HB2  . ASN A 1 191 ? -14.15142 -11.51983 14.55404 1.000 20.88558 ? 214 ASN A HB2  1 
ATOM   3024 H  HB3  . ASN A 1 191 ? -14.53514 -12.21342 13.17669 1.000 20.88558 ? 214 ASN A HB3  1 
ATOM   3025 H  HD21 . ASN A 1 191 ? -12.09165 -10.50482 11.74996 1.000 22.54457 ? 214 ASN A HD21 1 
ATOM   3026 H  HD22 . ASN A 1 191 ? -12.58381 -11.85652 12.13661 1.000 22.54457 ? 214 ASN A HD22 1 
ATOM   3027 N  N    . THR A 1 192 ? -16.54317 -9.31705  11.99513 1.000 18.98041 ? 215 THR A N    1 
ATOM   3028 C  CA   . THR A 1 192 ? -17.04963 -8.94566  10.68458 1.000 20.23661 ? 215 THR A CA   1 
ATOM   3029 C  C    . THR A 1 192 ? -15.94962 -8.70014  9.65052  1.000 20.72412 ? 215 THR A C    1 
ATOM   3030 O  O    . THR A 1 192 ? -16.26951 -8.46819  8.48152  1.000 24.53172 ? 215 THR A O    1 
ATOM   3031 C  CB   . THR A 1 192 ? -17.94429 -7.69869  10.78248 1.000 22.53816 ? 215 THR A CB   1 
ATOM   3032 O  OG1  . THR A 1 192 ? -17.14206 -6.53160  11.01971 1.000 21.82404 ? 215 THR A OG1  1 
ATOM   3033 C  CG2  . THR A 1 192 ? -18.97835 -7.84605  11.89446 1.000 23.55183 ? 215 THR A CG2  1 
ATOM   3034 H  H    . THR A 1 192 ? -16.28200 -8.65109  12.47251 1.000 22.77649 ? 215 THR A H    1 
ATOM   3035 H  HA   . THR A 1 192 ? -17.59581 -9.67996  10.36303 1.000 24.28393 ? 215 THR A HA   1 
ATOM   3036 H  HB   . THR A 1 192 ? -18.42157 -7.59103  9.94492  1.000 27.04579 ? 215 THR A HB   1 
ATOM   3037 H  HG1  . THR A 1 192 ? -16.84183 -6.54394  11.80413 1.000 26.18885 ? 215 THR A HG1  1 
ATOM   3038 H  HG21 . THR A 1 192 ? -19.58626 -7.09024  11.88448 1.000 28.26220 ? 215 THR A HG21 1 
ATOM   3039 H  HG22 . THR A 1 192 ? -19.48794 -8.66161  11.76767 1.000 28.26220 ? 215 THR A HG22 1 
ATOM   3040 H  HG23 . THR A 1 192 ? -18.53544 -7.88243  12.75668 1.000 28.26220 ? 215 THR A HG23 1 
ATOM   3041 N  N    A THR A 1 193 ? -14.67607 -8.77833  10.06091 0.783 20.94023 ? 216 THR A N    1 
ATOM   3042 N  N    B THR A 1 193 ? -14.67472 -8.77317  10.02955 0.217 21.16011 ? 216 THR A N    1 
ATOM   3043 C  CA   A THR A 1 193 ? -13.54438 -8.28252  9.28662  0.783 22.58597 ? 216 THR A CA   1 
ATOM   3044 C  CA   B THR A 1 193 ? -13.58758 -8.29036  9.18404  0.217 21.62128 ? 216 THR A CA   1 
ATOM   3045 C  C    A THR A 1 193 ? -12.60887 -9.37376  8.76231  0.783 21.56493 ? 216 THR A C    1 
ATOM   3046 C  C    B THR A 1 193 ? -12.70730 -9.38498  8.58896  0.217 20.45303 ? 216 THR A C    1 
ATOM   3047 O  O    A THR A 1 193 ? -11.54737 -9.04124  8.21732  0.783 22.93338 ? 216 THR A O    1 
ATOM   3048 O  O    B THR A 1 193 ? -11.83504 -9.07320  7.77000  0.217 21.59389 ? 216 THR A O    1 
ATOM   3049 C  CB   A THR A 1 193 ? -12.69769 -7.33217  10.14463 0.783 22.30120 ? 216 THR A CB   1 
ATOM   3050 C  CB   B THR A 1 193 ? -12.71522 -7.31873  9.99871  0.217 22.38072 ? 216 THR A CB   1 
ATOM   3051 O  OG1  A THR A 1 193 ? -11.89699 -8.09769  11.07197 0.783 22.52088 ? 216 THR A OG1  1 
ATOM   3052 O  OG1  B THR A 1 193 ? -13.51205 -6.21291  10.45063 0.217 23.24031 ? 216 THR A OG1  1 
ATOM   3053 C  CG2  A THR A 1 193 ? -13.56665 -6.37050  10.96591 0.783 24.58227 ? 216 THR A CG2  1 
ATOM   3054 C  CG2  B THR A 1 193 ? -11.55446 -6.78982  9.18217  0.217 23.08243 ? 216 THR A CG2  1 
ATOM   3055 H  H    A THR A 1 193 ? -14.44074 -9.12736  10.81085 0.783 25.12828 ? 216 THR A H    1 
ATOM   3056 H  H    B THR A 1 193 ? -14.41290 -9.10184  10.77990 0.217 25.39214 ? 216 THR A H    1 
ATOM   3057 H  HA   A THR A 1 193 ? -13.92111 -7.81447  8.52511  0.783 27.10316 ? 216 THR A HA   1 
ATOM   3058 H  HA   B THR A 1 193 ? -13.97951 -7.82080  8.43118  0.217 25.94553 ? 216 THR A HA   1 
ATOM   3059 H  HB   A THR A 1 193 ? -12.13831 -6.81080  9.54783  0.783 26.76144 ? 216 THR A HB   1 
ATOM   3060 H  HB   B THR A 1 193 ? -12.35047 -7.79706  10.75967 0.217 26.85686 ? 216 THR A HB   1 
ATOM   3061 H  HG1  A THR A 1 193 ? -11.18645 -8.34734  10.69994 0.783 27.02506 ? 216 THR A HG1  1 
ATOM   3062 H  HG1  B THR A 1 193 ? -13.79248 -6.35988  11.22867 0.217 27.88837 ? 216 THR A HG1  1 
ATOM   3063 H  HG21 A THR A 1 193 ? -13.00975 -5.69593  11.38510 0.783 29.49873 ? 216 THR A HG21 1 
ATOM   3064 H  HG21 B THR A 1 193 ? -11.18715 -5.99665  9.60274  0.217 27.69891 ? 216 THR A HG21 1 
ATOM   3065 H  HG22 A THR A 1 193 ? -14.21209 -5.93216  10.38957 0.783 29.49873 ? 216 THR A HG22 1 
ATOM   3066 H  HG22 B THR A 1 193 ? -10.85920 -7.46325  9.11896  0.217 27.69891 ? 216 THR A HG22 1 
ATOM   3067 H  HG23 A THR A 1 193 ? -14.04176 -6.85962  11.65579 0.783 29.49873 ? 216 THR A HG23 1 
ATOM   3068 H  HG23 B THR A 1 193 ? -11.85425 -6.56198  8.28824  0.217 27.69891 ? 216 THR A HG23 1 
ATOM   3069 N  N    . GLY A 1 194 ? -12.96725 -10.65342 8.87415  1.000 17.46156 ? 217 GLY A N    1 
ATOM   3070 C  CA   . GLY A 1 194 ? -11.98627 -11.70773 8.64383  1.000 13.56644 ? 217 GLY A CA   1 
ATOM   3071 C  C    . GLY A 1 194 ? -12.20842 -12.62528 7.45079  1.000 12.57094 ? 217 GLY A C    1 
ATOM   3072 O  O    . GLY A 1 194 ? -11.41860 -13.55023 7.22398  1.000 12.10918 ? 217 GLY A O    1 
ATOM   3073 H  H    . GLY A 1 194 ? -13.75433 -10.93392 9.07767  1.000 20.95387 ? 217 GLY A H    1 
ATOM   3074 H  HA2  . GLY A 1 194 ? -11.11914 -11.29003 8.52340  1.000 16.27973 ? 217 GLY A HA2  1 
ATOM   3075 H  HA3  . GLY A 1 194 ? -11.95889 -12.27022 9.43361  1.000 16.27973 ? 217 GLY A HA3  1 
ATOM   3076 N  N    . ALA A 1 195 ? -13.25698 -12.39201 6.66730  1.000 12.29981 ? 218 ALA A N    1 
ATOM   3077 C  CA   . ALA A 1 195 ? -13.63962 -13.36528 5.65323  1.000 12.03669 ? 218 ALA A CA   1 
ATOM   3078 C  C    . ALA A 1 195 ? -12.61826 -13.50658 4.53412  1.000 11.21872 ? 218 ALA A C    1 
ATOM   3079 O  O    . ALA A 1 195 ? -12.60980 -14.55075 3.87683  1.000 12.55692 ? 218 ALA A O    1 
ATOM   3080 C  CB   . ALA A 1 195 ? -15.00374 -12.99236 5.07257  1.000 13.49858 ? 218 ALA A CB   1 
ATOM   3081 H  H    . ALA A 1 195 ? -13.75381 -11.69092 6.70238  1.000 14.75977 ? 218 ALA A H    1 
ATOM   3082 H  HA   . ALA A 1 195 ? -13.71145 -14.23407 6.07861  1.000 14.44403 ? 218 ALA A HA   1 
ATOM   3083 H  HB1  . ALA A 1 195 ? -15.26452 -13.66359 4.42269  1.000 16.19829 ? 218 ALA A HB1  1 
ATOM   3084 H  HB2  . ALA A 1 195 ? -15.65413 -12.95761 5.79137  1.000 16.19829 ? 218 ALA A HB2  1 
ATOM   3085 H  HB3  . ALA A 1 195 ? -14.93795 -12.12476 4.64378  1.000 16.19829 ? 218 ALA A HB3  1 
ATOM   3086 N  N    . ALA A 1 196 ? -11.80187 -12.48811 4.28563  1.000 10.88626 ? 219 ALA A N    1 
ATOM   3087 C  CA   . ALA A 1 196 ? -10.81361 -12.53339 3.21929  1.000 11.59648 ? 219 ALA A CA   1 
ATOM   3088 C  C    . ALA A 1 196 ? -9.45631  -13.06149 3.67522  1.000 10.61972 ? 219 ALA A C    1 
ATOM   3089 O  O    . ALA A 1 196 ? -8.55264  -13.18769 2.85022  1.000 12.17516 ? 219 ALA A O    1 
ATOM   3090 C  CB   . ALA A 1 196 ? -10.63028 -11.14318 2.60384  1.000 13.30095 ? 219 ALA A CB   1 
ATOM   3091 H  H    . ALA A 1 196 ? -11.80263 -11.75068 4.72811  1.000 13.06351 ? 219 ALA A H    1 
ATOM   3092 H  HA   . ALA A 1 196 ? -11.14683 -13.12774 2.52891  1.000 13.91577 ? 219 ALA A HA   1 
ATOM   3093 H  HB1  . ALA A 1 196 ? -9.98357  -11.19967 1.88309  1.000 15.96114 ? 219 ALA A HB1  1 
ATOM   3094 H  HB2  . ALA A 1 196 ? -11.48324 -10.83526 2.25954  1.000 15.96114 ? 219 ALA A HB2  1 
ATOM   3095 H  HB3  . ALA A 1 196 ? -10.31061 -10.53453 3.28814  1.000 15.96114 ? 219 ALA A HB3  1 
ATOM   3096 N  N    . SER A 1 197 ? -9.28098  -13.36345 4.95690  1.000 10.32560 ? 220 SER A N    1 
ATOM   3097 C  CA   . SER A 1 197 ? -7.98114  -13.76791 5.48882  1.000 10.24914 ? 220 SER A CA   1 
ATOM   3098 C  C    . SER A 1 197 ? -7.95401  -15.27656 5.72417  1.000 9.94324  ? 220 SER A C    1 
ATOM   3099 O  O    . SER A 1 197 ? -8.15990  -16.03375 4.77454  1.000 10.22749 ? 220 SER A O    1 
ATOM   3100 C  CB   . SER A 1 197 ? -7.66016  -12.89502 6.69877  1.000 9.98222  ? 220 SER A CB   1 
ATOM   3101 O  OG   . SER A 1 197 ? -7.55584  -11.53533 6.28760  1.000 11.45120 ? 220 SER A OG   1 
ATOM   3102 H  H    . SER A 1 197 ? -9.90547  -13.34221 5.54780  1.000 12.39072 ? 220 SER A H    1 
ATOM   3103 H  HA   . SER A 1 197 ? -7.25305  -13.61842 4.86557  1.000 12.29896 ? 220 SER A HA   1 
ATOM   3104 H  HB2  . SER A 1 197 ? -8.37095  -12.97920 7.35345  1.000 11.97866 ? 220 SER A HB2  1 
ATOM   3105 H  HB3  . SER A 1 197 ? -6.81735  -13.17936 7.08571  1.000 11.97866 ? 220 SER A HB3  1 
ATOM   3106 H  HG   . SER A 1 197 ? -8.28261  -11.27989 5.95270  1.000 13.74144 ? 220 SER A HG   1 
ATOM   3107 N  N    . ILE A 1 198 ? -7.65901  -15.74189 6.93717  1.000 9.29077  ? 221 ILE A N    1 
ATOM   3108 C  CA   . ILE A 1 198 ? -7.57356  -17.18741 7.14406  1.000 9.73939  ? 221 ILE A CA   1 
ATOM   3109 C  C    . ILE A 1 198 ? -8.80744  -17.91011 6.61831  1.000 10.02711 ? 221 ILE A C    1 
ATOM   3110 O  O    . ILE A 1 198 ? -8.69639  -18.96367 5.98255  1.000 10.53245 ? 221 ILE A O    1 
ATOM   3111 C  CB   . ILE A 1 198 ? -7.28686  -17.51083 8.62954  1.000 9.50548  ? 221 ILE A CB   1 
ATOM   3112 C  CG1  . ILE A 1 198 ? -5.83167  -17.18971 8.95545  1.000 8.86433  ? 221 ILE A CG1  1 
ATOM   3113 C  CG2  . ILE A 1 198 ? -7.66287  -18.94225 8.95810  1.000 9.98493  ? 221 ILE A CG2  1 
ATOM   3114 C  CD1  . ILE A 1 198 ? -5.53481  -17.14920 10.43070 1.000 10.07703 ? 221 ILE A CD1  1 
ATOM   3115 H  H    . ILE A 1 198 ? -7.50896  -15.25977 7.63333  1.000 11.14892 ? 221 ILE A H    1 
ATOM   3116 H  HA   . ILE A 1 198 ? -6.82275  -17.51371 6.62376  1.000 11.68727 ? 221 ILE A HA   1 
ATOM   3117 H  HB   . ILE A 1 198 ? -7.84263  -16.94918 9.19219  1.000 11.40658 ? 221 ILE A HB   1 
ATOM   3118 H  HG12 . ILE A 1 198 ? -5.26573  -17.87002 8.55823  1.000 10.63719 ? 221 ILE A HG12 1 
ATOM   3119 H  HG13 . ILE A 1 198 ? -5.61400  -16.31974 8.58575  1.000 10.63719 ? 221 ILE A HG13 1 
ATOM   3120 H  HG21 . ILE A 1 198 ? -7.29802  -19.17318 9.82670  1.000 11.98192 ? 221 ILE A HG21 1 
ATOM   3121 H  HG22 . ILE A 1 198 ? -8.62969  -19.01901 8.97441  1.000 11.98192 ? 221 ILE A HG22 1 
ATOM   3122 H  HG23 . ILE A 1 198 ? -7.29588  -19.52911 8.27853  1.000 11.98192 ? 221 ILE A HG23 1 
ATOM   3123 H  HD11 . ILE A 1 198 ? -4.60856  -16.89157 10.55948 1.000 12.09243 ? 221 ILE A HD11 1 
ATOM   3124 H  HD12 . ILE A 1 198 ? -6.12017  -16.50115 10.85294 1.000 12.09243 ? 221 ILE A HD12 1 
ATOM   3125 H  HD13 . ILE A 1 198 ? -5.68888  -18.02938 10.80812 1.000 12.09243 ? 221 ILE A HD13 1 
ATOM   3126 N  N    . GLN A 1 199 ? -9.99540  -17.38086 6.90199  1.000 9.53896  ? 222 GLN A N    1 
ATOM   3127 C  CA   . GLN A 1 199 ? -11.23243 -18.02276 6.48049  1.000 11.17831 ? 222 GLN A CA   1 
ATOM   3128 C  C    . GLN A 1 199 ? -11.27536 -18.30279 4.98180  1.000 10.65863 ? 222 GLN A C    1 
ATOM   3129 O  O    . GLN A 1 199 ? -11.87572 -19.29075 4.55963  1.000 11.85187 ? 222 GLN A O    1 
ATOM   3130 C  CB   . GLN A 1 199 ? -12.41627 -17.10946 6.80448  1.000 12.46384 ? 222 GLN A CB   1 
ATOM   3131 C  CG   . GLN A 1 199 ? -12.82574 -17.04252 8.24442  1.000 16.08595 ? 222 GLN A CG   1 
ATOM   3132 C  CD   . GLN A 1 199 ? -13.89853 -15.99069 8.48733  1.000 18.16630 ? 222 GLN A CD   1 
ATOM   3133 O  OE1  . GLN A 1 199 ? -14.89226 -15.93393 7.77730  1.000 19.52458 ? 222 GLN A OE1  1 
ATOM   3134 N  NE2  . GLN A 1 199 ? -13.67052 -15.12227 9.47173  1.000 18.97609 ? 222 GLN A NE2  1 
ATOM   3135 H  H    . GLN A 1 199 ? -10.11164 -16.64899 7.33840  1.000 11.44675 ? 222 GLN A H    1 
ATOM   3136 H  HA   . GLN A 1 199 ? -11.30051 -18.86272 6.96084  1.000 13.41398 ? 222 GLN A HA   1 
ATOM   3137 H  HB2  . GLN A 1 199 ? -12.18616 -16.20778 6.53076  1.000 14.95661 ? 222 GLN A HB2  1 
ATOM   3138 H  HB3  . GLN A 1 199 ? -13.18544 -17.42228 6.30306  1.000 14.95661 ? 222 GLN A HB3  1 
ATOM   3139 H  HG2  . GLN A 1 199 ? -13.17987 -17.90401 8.51520  1.000 19.30314 ? 222 GLN A HG2  1 
ATOM   3140 H  HG3  . GLN A 1 199 ? -12.05275 -16.81676 8.78517  1.000 19.30314 ? 222 GLN A HG3  1 
ATOM   3141 H  HE21 . GLN A 1 199 ? -12.94596 -15.17458 9.93204  1.000 22.77131 ? 222 GLN A HE21 1 
ATOM   3142 H  HE22 . GLN A 1 199 ? -14.24789 -14.50942 9.64682  1.000 22.77131 ? 222 GLN A HE22 1 
ATOM   3143 N  N    . ALA A 1 200 ? -10.66146 -17.43851 4.16715  1.000 10.46748 ? 223 ALA A N    1 
ATOM   3144 C  CA   . ALA A 1 200 ? -10.67665 -17.59795 2.71867  1.000 11.10173 ? 223 ALA A CA   1 
ATOM   3145 C  C    . ALA A 1 200 ? -9.83848  -18.77354 2.24952  1.000 12.05863 ? 223 ALA A C    1 
ATOM   3146 O  O    . ALA A 1 200 ? -10.00454 -19.20214 1.09338  1.000 13.83428 ? 223 ALA A O    1 
ATOM   3147 C  CB   . ALA A 1 200 ? -10.24359 -16.28522 2.06485  1.000 10.81075 ? 223 ALA A CB   1 
ATOM   3148 H  H    . ALA A 1 200 ? -10.22647 -16.74666 4.43497  1.000 12.56097 ? 223 ALA A H    1 
ATOM   3149 H  HA   . ALA A 1 200 ? -11.57937 -17.77852 2.41309  1.000 13.32208 ? 223 ALA A HA   1 
ATOM   3150 H  HB1  . ALA A 1 200 ? -10.15508 -16.42276 1.10874  1.000 12.97290 ? 223 ALA A HB1  1 
ATOM   3151 H  HB2  . ALA A 1 200 ? -10.91544 -15.60807 2.24083  1.000 12.97290 ? 223 ALA A HB2  1 
ATOM   3152 H  HB3  . ALA A 1 200 ? -9.39193  -16.01152 2.43989  1.000 12.97290 ? 223 ALA A HB3  1 
ATOM   3153 N  N    . GLY A 1 201 ? -8.99638  -19.33667 3.11241  1.000 11.14786 ? 224 GLY A N    1 
ATOM   3154 C  CA   . GLY A 1 201 ? -8.22003  -20.51291 2.78981  1.000 10.81297 ? 224 GLY A CA   1 
ATOM   3155 C  C    . GLY A 1 201 ? -8.74510  -21.81359 3.33696  1.000 10.62634 ? 224 GLY A C    1 
ATOM   3156 O  O    . GLY A 1 201 ? -8.07240  -22.84328 3.19772  1.000 12.56702 ? 224 GLY A O    1 
ATOM   3157 H  H    . GLY A 1 201 ? -8.85941  -19.04268 3.90891  1.000 13.37743 ? 224 GLY A H    1 
ATOM   3158 H  HA2  . GLY A 1 201 ? -8.17822  -20.59780 1.82444  1.000 12.97556 ? 224 GLY A HA2  1 
ATOM   3159 H  HA3  . GLY A 1 201 ? -7.32177  -20.39206 3.13540  1.000 12.97556 ? 224 GLY A HA3  1 
ATOM   3160 N  N    . LEU A 1 202 ? -9.90927  -21.79853 3.97295  1.000 10.82433 ? 225 LEU A N    1 
ATOM   3161 C  CA   . LEU A 1 202 ? -10.49991 -22.95650 4.60976  1.000 11.02206 ? 225 LEU A CA   1 
ATOM   3162 C  C    . LEU A 1 202 ? -11.83291 -23.29913 3.96085  1.000 12.06169 ? 225 LEU A C    1 
ATOM   3163 O  O    . LEU A 1 202 ? -12.50341 -22.42360 3.39867  1.000 12.16498 ? 225 LEU A O    1 
ATOM   3164 C  CB   . LEU A 1 202 ? -10.78071 -22.65635 6.08958  1.000 11.86945 ? 225 LEU A CB   1 
ATOM   3165 C  CG   . LEU A 1 202 ? -9.60892  -22.11252 6.90675  1.000 12.49457 ? 225 LEU A CG   1 
ATOM   3166 C  CD1  . LEU A 1 202 ? -10.05849 -21.81058 8.33127  1.000 14.40597 ? 225 LEU A CD1  1 
ATOM   3167 C  CD2  . LEU A 1 202 ? -8.47419  -23.11097 6.89531  1.000 14.00783 ? 225 LEU A CD2  1 
ATOM   3168 H  H    . LEU A 1 202 ? -10.39591 -21.09372 4.05056  1.000 12.98919 ? 225 LEU A H    1 
ATOM   3169 H  HA   . LEU A 1 202 ? -9.89724  -23.71189 4.52552  1.000 13.22647 ? 225 LEU A HA   1 
ATOM   3170 H  HB2  . LEU A 1 202 ? -11.49006 -21.99618 6.13333  1.000 14.24334 ? 225 LEU A HB2  1 
ATOM   3171 H  HB3  . LEU A 1 202 ? -11.06729 -23.47989 6.51450  1.000 14.24334 ? 225 LEU A HB3  1 
ATOM   3172 H  HG   . LEU A 1 202 ? -9.28785  -21.28447 6.51668  1.000 14.99349 ? 225 LEU A HG   1 
ATOM   3173 H  HD11 . LEU A 1 202 ? -9.28057  -21.59411 8.86875  1.000 17.28717 ? 225 LEU A HD11 1 
ATOM   3174 H  HD12 . LEU A 1 202 ? -10.67020 -21.05791 8.31654  1.000 17.28717 ? 225 LEU A HD12 1 
ATOM   3175 H  HD13 . LEU A 1 202 ? -10.50419 -22.59199 8.69410  1.000 17.28717 ? 225 LEU A HD13 1 
ATOM   3176 H  HD21 . LEU A 1 202 ? -7.76978  -22.79522 7.48269  1.000 16.80940 ? 225 LEU A HD21 1 
ATOM   3177 H  HD22 . LEU A 1 202 ? -8.80473  -23.96826 7.20629  1.000 16.80940 ? 225 LEU A HD22 1 
ATOM   3178 H  HD23 . LEU A 1 202 ? -8.13682  -23.19526 5.98979  1.000 16.80940 ? 225 LEU A HD23 1 
ATOM   3179 N  N    . PRO A 1 203 ? -12.25162 -24.55818 4.03549  1.000 11.91612 ? 226 PRO A N    1 
ATOM   3180 C  CA   . PRO A 1 203 ? -13.58184 -24.92105 3.54532  1.000 11.51176 ? 226 PRO A CA   1 
ATOM   3181 C  C    . PRO A 1 203 ? -14.67834 -24.08151 4.18515  1.000 11.81853 ? 226 PRO A C    1 
ATOM   3182 O  O    . PRO A 1 203 ? -14.57859 -23.64757 5.33481  1.000 13.35284 ? 226 PRO A O    1 
ATOM   3183 C  CB   . PRO A 1 203 ? -13.71671 -26.39658 3.94517  1.000 12.88688 ? 226 PRO A CB   1 
ATOM   3184 C  CG   . PRO A 1 203 ? -12.28735 -26.89273 3.99719  1.000 13.29583 ? 226 PRO A CG   1 
ATOM   3185 C  CD   . PRO A 1 203 ? -11.52296 -25.72247 4.57538  1.000 12.45131 ? 226 PRO A CD   1 
ATOM   3186 H  HA   . PRO A 1 203 ? -13.61957 -24.82448 2.58088  1.000 13.81411 ? 226 PRO A HA   1 
ATOM   3187 H  HB2  . PRO A 1 203 ? -14.14554 -26.47024 4.81211  1.000 15.46426 ? 226 PRO A HB2  1 
ATOM   3188 H  HB3  . PRO A 1 203 ? -14.23126 -26.87798 3.27854  1.000 15.46426 ? 226 PRO A HB3  1 
ATOM   3189 H  HG2  . PRO A 1 203 ? -12.22307 -27.67234 4.57077  1.000 15.95500 ? 226 PRO A HG2  1 
ATOM   3190 H  HG3  . PRO A 1 203 ? -11.97469 -27.11047 3.10515  1.000 15.95500 ? 226 PRO A HG3  1 
ATOM   3191 H  HD2  . PRO A 1 203 ? -11.55390 -25.73242 5.54484  1.000 14.94158 ? 226 PRO A HD2  1 
ATOM   3192 H  HD3  . PRO A 1 203 ? -10.60136 -25.72613 4.27281  1.000 14.94158 ? 226 PRO A HD3  1 
ATOM   3193 N  N    . ALA A 1 204 ? -15.75508 -23.91524 3.42511  1.000 12.73830 ? 227 ALA A N    1 
ATOM   3194 C  CA   . ALA A 1 204 ? -16.88271 -23.11432 3.87583  1.000 15.04740 ? 227 ALA A CA   1 
ATOM   3195 C  C    . ALA A 1 204 ? -17.53473 -23.66665 5.13007  1.000 16.34266 ? 227 ALA A C    1 
ATOM   3196 O  O    . ALA A 1 204 ? -18.10715 -22.89798 5.90978  1.000 19.56282 ? 227 ALA A O    1 
ATOM   3197 C  CB   . ALA A 1 204 ? -17.91771 -23.02293 2.75966  1.000 16.83533 ? 227 ALA A CB   1 
ATOM   3198 H  H    . ALA A 1 204 ? -15.85771 -24.25649 2.64241  1.000 15.28596 ? 227 ALA A H    1 
ATOM   3199 H  HA   . ALA A 1 204 ? -16.55521 -22.22597 4.08673  1.000 18.05689 ? 227 ALA A HA   1 
ATOM   3200 H  HB1  . ALA A 1 204 ? -18.64524 -22.45067 3.04968  1.000 20.20239 ? 227 ALA A HB1  1 
ATOM   3201 H  HB2  . ALA A 1 204 ? -17.49765 -22.64904 1.96931  1.000 20.20239 ? 227 ALA A HB2  1 
ATOM   3202 H  HB3  . ALA A 1 204 ? -18.25326 -23.91232 2.56654  1.000 20.20239 ? 227 ALA A HB3  1 
ATOM   3203 N  N    . SER A 1 205 ? -17.46402 -24.98027 5.35266  1.000 16.11629 ? 228 SER A N    1 
ATOM   3204 C  CA   . SER A 1 205 ? -18.15479 -25.57888 6.48716  1.000 17.94699 ? 228 SER A CA   1 
ATOM   3205 C  C    . SER A 1 205 ? -17.43181 -25.35280 7.80945  1.000 18.33367 ? 228 SER A C    1 
ATOM   3206 O  O    . SER A 1 205 ? -18.01875 -25.57409 8.87803  1.000 21.55261 ? 228 SER A O    1 
ATOM   3207 C  CB   . SER A 1 205 ? -18.29663 -27.08263 6.28209  1.000 19.58277 ? 228 SER A CB   1 
ATOM   3208 O  OG   . SER A 1 205 ? -17.03125 -27.72762 6.26402  1.000 20.47088 ? 228 SER A OG   1 
ATOM   3209 H  H    . SER A 1 205 ? -17.02672 -25.53769 4.86515  1.000 19.33955 ? 228 SER A H    1 
ATOM   3210 H  HA   . SER A 1 205 ? -19.03732 -25.17995 6.54106  1.000 21.53639 ? 228 SER A HA   1 
ATOM   3211 H  HB2  . SER A 1 205 ? -18.82453 -27.44925 7.00859  1.000 23.49932 ? 228 SER A HB2  1 
ATOM   3212 H  HB3  . SER A 1 205 ? -18.74161 -27.24249 5.43513  1.000 23.49932 ? 228 SER A HB3  1 
ATOM   3213 H  HG   . SER A 1 205 ? -16.62177 -27.53711 5.55576  1.000 24.56506 ? 228 SER A HG   1 
ATOM   3214 N  N    . TRP A 1 206 ? -16.17523 -24.94054 7.77691  1.000 15.89781 ? 229 TRP A N    1 
ATOM   3215 C  CA   . TRP A 1 206 ? -15.42864 -24.82697 9.01833  1.000 15.53729 ? 229 TRP A CA   1 
ATOM   3216 C  C    . TRP A 1 206 ? -15.82296 -23.55328 9.75293  1.000 15.97719 ? 229 TRP A C    1 
ATOM   3217 O  O    . TRP A 1 206 ? -16.12569 -22.53129 9.14441  1.000 19.34419 ? 229 TRP A O    1 
ATOM   3218 C  CB   . TRP A 1 206 ? -13.93351 -24.82743 8.73690  1.000 14.86446 ? 229 TRP A CB   1 
ATOM   3219 C  CG   . TRP A 1 206 ? -13.42444 -26.13813 8.17134  1.000 14.80761 ? 229 TRP A CG   1 
ATOM   3220 C  CD1  . TRP A 1 206 ? -14.15575 -27.15193 7.64319  1.000 16.18754 ? 229 TRP A CD1  1 
ATOM   3221 C  CD2  . TRP A 1 206 ? -12.05656 -26.54784 8.09363  1.000 13.66887 ? 229 TRP A CD2  1 
ATOM   3222 N  NE1  . TRP A 1 206 ? -13.32682 -28.17860 7.25159  1.000 15.97067 ? 229 TRP A NE1  1 
ATOM   3223 C  CE2  . TRP A 1 206 ? -12.02936 -27.82283 7.51313  1.000 14.98208 ? 229 TRP A CE2  1 
ATOM   3224 C  CE3  . TRP A 1 206 ? -10.85550 -25.95497 8.46766  1.000 14.38606 ? 229 TRP A CE3  1 
ATOM   3225 C  CZ2  . TRP A 1 206 ? -10.83651 -28.51168 7.28166  1.000 17.76001 ? 229 TRP A CZ2  1 
ATOM   3226 C  CZ3  . TRP A 1 206 ? -9.67780  -26.64116 8.24974  1.000 16.23978 ? 229 TRP A CZ3  1 
ATOM   3227 C  CH2  . TRP A 1 206 ? -9.67579  -27.90366 7.65409  1.000 18.27167 ? 229 TRP A CH2  1 
ATOM   3228 H  H    . TRP A 1 206 ? -15.74188 -24.72546 7.06590  1.000 19.07737 ? 229 TRP A H    1 
ATOM   3229 H  HA   . TRP A 1 206 ? -15.62501 -25.58331 9.59304  1.000 18.64475 ? 229 TRP A HA   1 
ATOM   3230 H  HB2  . TRP A 1 206 ? -13.73627 -24.12954 8.09273  1.000 17.83736 ? 229 TRP A HB2  1 
ATOM   3231 H  HB3  . TRP A 1 206 ? -13.45916 -24.65752 9.56577  1.000 17.83736 ? 229 TRP A HB3  1 
ATOM   3232 H  HD1  . TRP A 1 206 ? -15.08186 -27.15287 7.55822  1.000 19.42504 ? 229 TRP A HD1  1 
ATOM   3233 H  HE1  . TRP A 1 206 ? -13.58124 -28.92130 6.90049  1.000 19.16481 ? 229 TRP A HE1  1 
ATOM   3234 H  HE3  . TRP A 1 206 ? -10.84593 -25.11083 8.85784  1.000 17.26328 ? 229 TRP A HE3  1 
ATOM   3235 H  HZ2  . TRP A 1 206 ? -10.83478 -29.35420 6.88787  1.000 21.31201 ? 229 TRP A HZ2  1 
ATOM   3236 H  HZ3  . TRP A 1 206 ? -8.87085  -26.25531 8.50442  1.000 19.48774 ? 229 TRP A HZ3  1 
ATOM   3237 H  HH2  . TRP A 1 206 ? -8.86641  -28.33802 7.50872  1.000 21.92601 ? 229 TRP A HH2  1 
ATOM   3238 N  N    . VAL A 1 207 ? -15.83906 -23.62168 11.07531 1.000 15.30209 ? 230 VAL A N    1 
ATOM   3239 C  CA   . VAL A 1 207 ? -16.22885 -22.49036 11.91393 1.000 16.19582 ? 230 VAL A CA   1 
ATOM   3240 C  C    . VAL A 1 207 ? -14.96222 -21.80737 12.41366 1.000 14.62681 ? 230 VAL A C    1 
ATOM   3241 O  O    . VAL A 1 207 ? -14.02544 -22.47254 12.87414 1.000 14.83759 ? 230 VAL A O    1 
ATOM   3242 C  CB   . VAL A 1 207 ? -17.12473 -22.94949 13.07724 1.000 19.28994 ? 230 VAL A CB   1 
ATOM   3243 C  CG1  . VAL A 1 207 ? -17.41303 -21.78345 14.01509 1.000 20.95044 ? 230 VAL A CG1  1 
ATOM   3244 C  CG2  . VAL A 1 207 ? -18.41594 -23.54329 12.54353 1.000 21.30042 ? 230 VAL A CG2  1 
ATOM   3245 H  H    . VAL A 1 207 ? -15.62473 -24.32486 11.52163 1.000 18.36250 ? 230 VAL A H    1 
ATOM   3246 H  HA   . VAL A 1 207 ? -16.72883 -21.84663 11.38807 1.000 19.43498 ? 230 VAL A HA   1 
ATOM   3247 H  HB   . VAL A 1 207 ? -16.66320 -23.63610 13.58366 1.000 23.14793 ? 230 VAL A HB   1 
ATOM   3248 H  HG11 . VAL A 1 207 ? -18.10786 -22.04471 14.63947 1.000 25.14053 ? 230 VAL A HG11 1 
ATOM   3249 H  HG12 . VAL A 1 207 ? -16.60224 -21.55839 14.49765 1.000 25.14053 ? 230 VAL A HG12 1 
ATOM   3250 H  HG13 . VAL A 1 207 ? -17.70822 -21.02233 13.49119 1.000 25.14053 ? 230 VAL A HG13 1 
ATOM   3251 H  HG21 . VAL A 1 207 ? -18.95677 -23.84551 13.28990 1.000 25.56050 ? 230 VAL A HG21 1 
ATOM   3252 H  HG22 . VAL A 1 207 ? -18.89327 -22.86304 12.04321 1.000 25.56050 ? 230 VAL A HG22 1 
ATOM   3253 H  HG23 . VAL A 1 207 ? -18.20359 -24.29190 11.96439 1.000 25.56050 ? 230 VAL A HG23 1 
ATOM   3254 N  N    . VAL A 1 208 ? -14.92916 -20.48128 12.32848 1.000 13.60540 ? 231 VAL A N    1 
ATOM   3255 C  CA   . VAL A 1 208 ? -13.73467 -19.71073 12.63872 1.000 13.13653 ? 231 VAL A CA   1 
ATOM   3256 C  C    . VAL A 1 208 ? -14.09326 -18.57429 13.58041 1.000 12.42388 ? 231 VAL A C    1 
ATOM   3257 O  O    . VAL A 1 208 ? -15.07460 -17.85801 13.35593 1.000 14.89986 ? 231 VAL A O    1 
ATOM   3258 C  CB   . VAL A 1 208 ? -13.10124 -19.14363 11.35788 1.000 14.18801 ? 231 VAL A CB   1 
ATOM   3259 C  CG1  . VAL A 1 208 ? -11.93803 -18.22863 11.70722 1.000 14.98241 ? 231 VAL A CG1  1 
ATOM   3260 C  CG2  . VAL A 1 208 ? -12.65518 -20.27548 10.45086 1.000 16.14432 ? 231 VAL A CG2  1 
ATOM   3261 H  H    . VAL A 1 208 ? -15.59964 -19.99909 12.08860 1.000 16.32648 ? 231 VAL A H    1 
ATOM   3262 H  HA   . VAL A 1 208 ? -13.10011 -20.28507 13.09519 1.000 15.76383 ? 231 VAL A HA   1 
ATOM   3263 H  HB   . VAL A 1 208 ? -13.75892 -18.61716 10.87705 1.000 17.02561 ? 231 VAL A HB   1 
ATOM   3264 H  HG11 . VAL A 1 208 ? -11.44483 -18.02183 10.89796 1.000 17.97890 ? 231 VAL A HG11 1 
ATOM   3265 H  HG12 . VAL A 1 208 ? -12.28512 -17.41276 12.10065 1.000 17.97890 ? 231 VAL A HG12 1 
ATOM   3266 H  HG13 . VAL A 1 208 ? -11.35942 -18.68122 12.34068 1.000 17.97890 ? 231 VAL A HG13 1 
ATOM   3267 H  HG21 . VAL A 1 208 ? -12.21292 -19.90117 9.67292  1.000 19.37318 ? 231 VAL A HG21 1 
ATOM   3268 H  HG22 . VAL A 1 208 ? -12.04081 -20.84685 10.93766 1.000 19.37318 ? 231 VAL A HG22 1 
ATOM   3269 H  HG23 . VAL A 1 208 ? -13.43334 -20.78506 10.17572 1.000 19.37318 ? 231 VAL A HG23 1 
ATOM   3270 N  N    . GLY A 1 209 ? -13.28119 -18.39758 14.61583 1.000 11.22279 ? 232 GLY A N    1 
ATOM   3271 C  CA   . GLY A 1 209 ? -13.22250 -17.14550 15.32959 1.000 10.92315 ? 232 GLY A CA   1 
ATOM   3272 C  C    . GLY A 1 209 ? -11.86636 -16.53829 15.10069 1.000 10.56166 ? 232 GLY A C    1 
ATOM   3273 O  O    . GLY A 1 209 ? -10.85625 -17.19507 15.32033 1.000 12.37984 ? 232 GLY A O    1 
ATOM   3274 H  H    . GLY A 1 209 ? -12.74975 -18.99975 14.92336 1.000 13.46735 ? 232 GLY A H    1 
ATOM   3275 H  HA2  . GLY A 1 209 ? -13.90717 -16.53996 15.00489 1.000 13.10778 ? 232 GLY A HA2  1 
ATOM   3276 H  HA3  . GLY A 1 209 ? -13.35523 -17.29226 16.27919 1.000 13.10778 ? 232 GLY A HA3  1 
ATOM   3277 N  N    . ASP A 1 210 ? -11.80754 -15.31314 14.60939 1.000 9.62837  ? 233 ASP A N    1 
ATOM   3278 C  CA   . ASP A 1 210 ? -10.51739 -14.74288 14.25430 1.000 9.31034  ? 233 ASP A CA   1 
ATOM   3279 C  C    . ASP A 1 210 ? -10.49179 -13.25776 14.55802 1.000 8.93861  ? 233 ASP A C    1 
ATOM   3280 O  O    . ASP A 1 210 ? -11.51855 -12.62937 14.80442 1.000 9.61165  ? 233 ASP A O    1 
ATOM   3281 C  CB   . ASP A 1 210 ? -10.16189 -14.93921 12.76180 1.000 9.52715  ? 233 ASP A CB   1 
ATOM   3282 C  CG   . ASP A 1 210 ? -10.83009 -13.93074 11.87884 1.000 9.65091  ? 233 ASP A CG   1 
ATOM   3283 O  OD1  . ASP A 1 210 ? -12.06317 -13.96597 11.78434 1.000 11.53501 ? 233 ASP A OD1  1 
ATOM   3284 O  OD2  . ASP A 1 210 ? -10.13421 -13.07182 11.28538 1.000 9.90897  ? 233 ASP A OD2  1 
ATOM   3285 H  H    . ASP A 1 210 ? -12.48550 -14.80149 14.47455 1.000 11.55404 ? 233 ASP A H    1 
ATOM   3286 H  HA   . ASP A 1 210 ? -9.85156  -15.18979 14.80004 1.000 11.17241 ? 233 ASP A HA   1 
ATOM   3287 H  HB2  . ASP A 1 210 ? -9.20258  -14.84972 12.64946 1.000 11.43258 ? 233 ASP A HB2  1 
ATOM   3288 H  HB3  . ASP A 1 210 ? -10.44786 -15.82248 12.48081 1.000 11.43258 ? 233 ASP A HB3  1 
ATOM   3289 N  N    . LYS A 1 211 ? -9.27797  -12.72032 14.57763 1.000 8.74150  ? 234 LYS A N    1 
ATOM   3290 C  CA   . LYS A 1 211 ? -9.05496  -11.28198 14.62907 1.000 8.87812  ? 234 LYS A CA   1 
ATOM   3291 C  C    . LYS A 1 211 ? -7.96032  -10.92584 13.63982 1.000 8.92517  ? 234 LYS A C    1 
ATOM   3292 O  O    . LYS A 1 211 ? -6.83434  -11.41952 13.75073 1.000 8.98733  ? 234 LYS A O    1 
ATOM   3293 C  CB   . LYS A 1 211 ? -8.66756  -10.83034 16.03439 1.000 9.77200  ? 234 LYS A CB   1 
ATOM   3294 C  CG   . LYS A 1 211 ? -8.45681  -9.30874  16.11890 1.000 10.52899 ? 234 LYS A CG   1 
ATOM   3295 C  CD   . LYS A 1 211 ? -9.76308  -8.54261  16.04746 1.000 10.95805 ? 234 LYS A CD   1 
ATOM   3296 C  CE   . LYS A 1 211 ? -9.57384  -7.06578  15.73017 1.000 11.39188 ? 234 LYS A CE   1 
ATOM   3297 N  NZ   . LYS A 1 211 ? -9.38517  -6.85709  14.27085 1.000 11.60830 ? 234 LYS A NZ   1 
ATOM   3298 H  H    . LYS A 1 211 ? -8.55082  -13.17923 14.56150 1.000 10.48981 ? 234 LYS A H    1 
ATOM   3299 H  HA   . LYS A 1 211 ? -9.86872  -10.82128 14.37128 1.000 10.65375 ? 234 LYS A HA   1 
ATOM   3300 H  HB2  . LYS A 1 211 ? -9.37488  -11.07273 16.65233 1.000 11.72640 ? 234 LYS A HB2  1 
ATOM   3301 H  HB3  . LYS A 1 211 ? -7.83939  -11.26533 16.29094 1.000 11.72640 ? 234 LYS A HB3  1 
ATOM   3302 H  HG2  . LYS A 1 211 ? -8.02654  -9.09327  16.96113 1.000 12.63479 ? 234 LYS A HG2  1 
ATOM   3303 H  HG3  . LYS A 1 211 ? -7.89882  -9.02307  15.37867 1.000 12.63479 ? 234 LYS A HG3  1 
ATOM   3304 H  HD2  . LYS A 1 211 ? -10.31688 -8.92841  15.35078 1.000 13.14966 ? 234 LYS A HD2  1 
ATOM   3305 H  HD3  . LYS A 1 211 ? -10.21386 -8.60793  16.90387 1.000 13.14966 ? 234 LYS A HD3  1 
ATOM   3306 H  HE2  . LYS A 1 211 ? -10.35894 -6.57109  16.01265 1.000 13.67025 ? 234 LYS A HE2  1 
ATOM   3307 H  HE3  . LYS A 1 211 ? -8.78838  -6.73372  16.19244 1.000 13.67025 ? 234 LYS A HE3  1 
ATOM   3308 H  HZ1  . LYS A 1 211 ? -8.69214  -7.33503  13.98209 1.000 13.92995 ? 234 LYS A HZ1  1 
ATOM   3309 H  HZ2  . LYS A 1 211 ? -10.11526 -7.11159  13.83006 1.000 13.92995 ? 234 LYS A HZ2  1 
ATOM   3310 H  HZ3  . LYS A 1 211 ? -9.23218  -5.99642  14.10371 1.000 13.92995 ? 234 LYS A HZ3  1 
ATOM   3311 N  N    . THR A 1 212 ? -8.27150  -10.03295 12.70887 1.000 8.99546  ? 235 THR A N    1 
ATOM   3312 C  CA   . THR A 1 212 ? -7.29762  -9.57161  11.73521 1.000 9.43001  ? 235 THR A CA   1 
ATOM   3313 C  C    . THR A 1 212 ? -6.51108  -8.36514  12.24947 1.000 9.19511  ? 235 THR A C    1 
ATOM   3314 O  O    . THR A 1 212 ? -6.87265  -7.70549  13.22435 1.000 9.79263  ? 235 THR A O    1 
ATOM   3315 C  CB   . THR A 1 212 ? -7.96757  -9.16281  10.42430 1.000 11.65570 ? 235 THR A CB   1 
ATOM   3316 O  OG1  . THR A 1 212 ? -8.86647  -8.08918  10.67808 1.000 14.82536 ? 235 THR A OG1  1 
ATOM   3317 C  CG2  . THR A 1 212 ? -8.70369  -10.32501 9.75936  1.000 12.96208 ? 235 THR A CG2  1 
ATOM   3318 H  H    . THR A 1 212 ? -9.04926  -9.67660  12.62111 1.000 10.79455 ? 235 THR A H    1 
ATOM   3319 H  HA   . THR A 1 212 ? -6.69221  -10.31275 11.57678 1.000 11.31601 ? 235 THR A HA   1 
ATOM   3320 H  HB   . THR A 1 212 ? -7.28471  -8.87995  9.79613  1.000 13.98684 ? 235 THR A HB   1 
ATOM   3321 H  HG1  . THR A 1 212 ? -8.44050  -7.41269  10.93598 1.000 17.79043 ? 235 THR A HG1  1 
ATOM   3322 H  HG21 . THR A 1 212 ? -9.12706  -10.02428 8.94008  1.000 15.55450 ? 235 THR A HG21 1 
ATOM   3323 H  HG22 . THR A 1 212 ? -8.07875  -11.03615 9.54810  1.000 15.55450 ? 235 THR A HG22 1 
ATOM   3324 H  HG23 . THR A 1 212 ? -9.38476  -10.67161 10.35678 1.000 15.55450 ? 235 THR A HG23 1 
ATOM   3325 N  N    . GLY A 1 213 ? -5.44032  -8.06365  11.53813 1.000 9.52818  ? 236 GLY A N    1 
ATOM   3326 C  CA   . GLY A 1 213 ? -4.66236  -6.86776  11.76027 1.000 10.34892 ? 236 GLY A CA   1 
ATOM   3327 C  C    . GLY A 1 213 ? -4.12342  -6.33430  10.46094 1.000 10.29519 ? 236 GLY A C    1 
ATOM   3328 O  O    . GLY A 1 213 ? -3.77188  -7.08330  9.56309  1.000 11.25766 ? 236 GLY A O    1 
ATOM   3329 H  H    . GLY A 1 213 ? -5.13543  -8.55330  10.90025 1.000 11.43382 ? 236 GLY A H    1 
ATOM   3330 H  HA2  . GLY A 1 213 ? -5.21796  -6.18709  12.17124 1.000 12.41870 ? 236 GLY A HA2  1 
ATOM   3331 H  HA3  . GLY A 1 213 ? -3.91788  -7.06597  12.34965 1.000 12.41870 ? 236 GLY A HA3  1 
ATOM   3332 N  N    A SER A 1 214 ? -3.99200  -5.00853  10.41265 0.337 10.32824 ? 237 SER A N    1 
ATOM   3333 N  N    B SER A 1 214 ? -4.04880  -5.00727  10.38148 0.170 10.57794 ? 237 SER A N    1 
ATOM   3334 N  N    C SER A 1 214 ? -4.07911  -5.00685  10.36040 0.492 10.41378 ? 237 SER A N    1 
ATOM   3335 C  CA   A SER A 1 214 ? -3.52877  -4.27650  9.24249  0.337 11.23423 ? 237 SER A CA   1 
ATOM   3336 C  CA   B SER A 1 214 ? -3.47778  -4.32411  9.22937  0.170 11.52592 ? 237 SER A CA   1 
ATOM   3337 C  CA   C SER A 1 214 ? -3.49396  -4.29859  9.23329  0.492 12.24115 ? 237 SER A CA   1 
ATOM   3338 C  C    A SER A 1 214 ? -2.72844  -3.06865  9.71224  0.337 10.27825 ? 237 SER A C    1 
ATOM   3339 C  C    B SER A 1 214 ? -2.71109  -3.10663  9.71840  0.170 10.81418 ? 237 SER A C    1 
ATOM   3340 C  C    C SER A 1 214 ? -2.67879  -3.12580  9.75786  0.492 10.40233 ? 237 SER A C    1 
ATOM   3341 O  O    A SER A 1 214 ? -3.13704  -2.37261  10.64583 0.337 10.85952 ? 237 SER A O    1 
ATOM   3342 O  O    B SER A 1 214 ? -3.12563  -2.44398  10.67333 0.170 11.37945 ? 237 SER A O    1 
ATOM   3343 O  O    C SER A 1 214 ? -3.01683  -2.51355  10.77802 0.492 11.31284 ? 237 SER A O    1 
ATOM   3344 C  CB   A SER A 1 214 ? -4.75292  -3.82327  8.43389  0.337 13.32628 ? 237 SER A CB   1 
ATOM   3345 C  CB   B SER A 1 214 ? -4.57190  -3.87470  8.25220  0.170 13.79447 ? 237 SER A CB   1 
ATOM   3346 C  CB   C SER A 1 214 ? -4.58168  -3.75315  8.28761  0.492 16.88151 ? 237 SER A CB   1 
ATOM   3347 O  OG   A SER A 1 214 ? -4.39113  -2.93834  7.40375  0.337 14.29863 ? 237 SER A OG   1 
ATOM   3348 O  OG   B SER A 1 214 ? -5.46449  -2.97872  8.88592  0.170 14.80488 ? 237 SER A OG   1 
ATOM   3349 O  OG   C SER A 1 214 ? -5.27881  -4.80190  7.64265  0.492 19.79431 ? 237 SER A OG   1 
ATOM   3350 H  H    A SER A 1 214 ? -4.17350  -4.49113  11.07518 0.337 12.39389 ? 237 SER A H    1 
ATOM   3351 H  H    B SER A 1 214 ? -4.32813  -4.47321  10.99496 0.170 12.69352 ? 237 SER A H    1 
ATOM   3352 H  H    C SER A 1 214 ? -4.39536  -4.47612  10.95865 0.492 12.49654 ? 237 SER A H    1 
ATOM   3353 H  HA   A SER A 1 214 ? -2.94584  -4.81736  8.68700  0.337 13.48107 ? 237 SER A HA   1 
ATOM   3354 H  HA   B SER A 1 214 ? -2.86905  -4.91691  8.76145  0.170 13.83110 ? 237 SER A HA   1 
ATOM   3355 H  HA   C SER A 1 214 ? -2.91395  -4.89967  8.74015  0.492 14.68938 ? 237 SER A HA   1 
ATOM   3356 H  HB2  A SER A 1 214 ? -5.17586  -4.60345  8.04231  0.337 15.99154 ? 237 SER A HB2  1 
ATOM   3357 H  HB2  B SER A 1 214 ? -4.15847  -3.42894  7.49637  0.170 16.55337 ? 237 SER A HB2  1 
ATOM   3358 H  HB2  C SER A 1 214 ? -5.21282  -3.22896  8.80508  0.492 20.25782 ? 237 SER A HB2  1 
ATOM   3359 H  HB3  A SER A 1 214 ? -5.37267  -3.37378  9.02952  0.337 15.99154 ? 237 SER A HB3  1 
ATOM   3360 H  HB3  B SER A 1 214 ? -5.06550  -4.65276  7.94911  0.170 16.55337 ? 237 SER A HB3  1 
ATOM   3361 H  HB3  C SER A 1 214 ? -4.16097  -3.19586  7.61432  0.492 20.25782 ? 237 SER A HB3  1 
ATOM   3362 H  HG   A SER A 1 214 ? -3.69965  -3.21608  7.01605  0.337 17.15835 ? 237 SER A HG   1 
ATOM   3363 H  HG   B SER A 1 214 ? -5.71834  -3.29754  9.62044  0.170 17.76586 ? 237 SER A HG   1 
ATOM   3364 H  HG   C SER A 1 214 ? -5.93726  -4.49324  7.22220  0.492 23.75317 ? 237 SER A HG   1 
ATOM   3365 N  N    . GLY A 1 215 ? -1.61524  -2.79441  9.04234  1.000 10.53711 ? 238 GLY A N    1 
ATOM   3366 C  CA   . GLY A 1 215 ? -0.76685  -1.71035  9.47348  1.000 11.42247 ? 238 GLY A CA   1 
ATOM   3367 C  C    . GLY A 1 215 ? 0.16827   -1.24571  8.38121  1.000 11.28327 ? 238 GLY A C    1 
ATOM   3368 O  O    . GLY A 1 215 ? 0.02589   -1.60639  7.20771  1.000 11.76501 ? 238 GLY A O    1 
ATOM   3369 H  H    . GLY A 1 215 ? -1.37181  -3.18079  8.31361  1.000 12.64453 ? 238 GLY A H    1 
ATOM   3370 H  HA2  . GLY A 1 215 ? -1.31732  -0.95917  9.74480  1.000 13.70696 ? 238 GLY A HA2  1 
ATOM   3371 H  HA3  . GLY A 1 215 ? -0.23336  -2.00040  10.22988 1.000 13.70696 ? 238 GLY A HA3  1 
ATOM   3372 N  N    . GLY A 1 216 ? 1.12570   -0.41455  8.78129  1.000 11.01220 ? 239 GLY A N    1 
ATOM   3373 C  CA   . GLY A 1 216 ? 2.11960   0.07924   7.85294  1.000 11.63804 ? 239 GLY A CA   1 
ATOM   3374 C  C    . GLY A 1 216 ? 2.93897   -1.05480  7.27407  1.000 11.17526 ? 239 GLY A C    1 
ATOM   3375 O  O    . GLY A 1 216 ? 2.90727   -2.19214  7.73832  1.000 11.34975 ? 239 GLY A O    1 
ATOM   3376 H  H    . GLY A 1 216 ? 1.21692   -0.12487  9.58588  1.000 13.21465 ? 239 GLY A H    1 
ATOM   3377 H  HA2  . GLY A 1 216 ? 1.68153   0.54869   7.12589  1.000 13.96565 ? 239 GLY A HA2  1 
ATOM   3378 H  HA3  . GLY A 1 216 ? 2.71656   0.69197   8.31022  1.000 13.96565 ? 239 GLY A HA3  1 
ATOM   3379 N  N    . TYR A 1 217 ? 3.68894   -0.73439  6.22631  1.000 11.87532 ? 240 TYR A N    1 
ATOM   3380 C  CA   . TYR A 1 217 ? 4.52650   -1.71787  5.55141  1.000 12.35540 ? 240 TYR A CA   1 
ATOM   3381 C  C    . TYR A 1 217 ? 3.69224   -2.88629  5.05486  1.000 11.75558 ? 240 TYR A C    1 
ATOM   3382 O  O    . TYR A 1 217 ? 4.14940   -4.01809  4.99623  1.000 11.70748 ? 240 TYR A O    1 
ATOM   3383 C  CB   . TYR A 1 217 ? 5.71009   -2.14539  6.41398  1.000 12.79978 ? 240 TYR A CB   1 
ATOM   3384 C  CG   . TYR A 1 217 ? 6.73340   -1.04062  6.50818  1.000 13.32087 ? 240 TYR A CG   1 
ATOM   3385 C  CD1  . TYR A 1 217 ? 6.57253   0.01421   7.41238  1.000 14.36977 ? 240 TYR A CD1  1 
ATOM   3386 C  CD2  . TYR A 1 217 ? 7.83805   -1.01905  5.67264  1.000 13.75261 ? 240 TYR A CD2  1 
ATOM   3387 C  CE1  . TYR A 1 217 ? 7.48650   1.04284   7.48819  1.000 15.61682 ? 240 TYR A CE1  1 
ATOM   3388 C  CE2  . TYR A 1 217 ? 8.77252   0.00660   5.74596  1.000 16.19314 ? 240 TYR A CE2  1 
ATOM   3389 C  CZ   . TYR A 1 217 ? 8.58950   1.03529   6.65055  1.000 16.69199 ? 240 TYR A CZ   1 
ATOM   3390 O  OH   . TYR A 1 217 ? 9.50402   2.06807   6.73519  1.000 20.03189 ? 240 TYR A OH   1 
ATOM   3391 H  H    . TYR A 1 217 ? 3.73003   0.05367   5.88444  1.000 14.25038 ? 240 TYR A H    1 
ATOM   3392 H  HA   . TYR A 1 217 ? 4.92376   -1.31580  4.76311  1.000 14.82648 ? 240 TYR A HA   1 
ATOM   3393 H  HB2  . TYR A 1 217 ? 5.39890   -2.35443  7.30861  1.000 15.35973 ? 240 TYR A HB2  1 
ATOM   3394 H  HB3  . TYR A 1 217 ? 6.13270   -2.92419  6.01930  1.000 15.35973 ? 240 TYR A HB3  1 
ATOM   3395 H  HD1  . TYR A 1 217 ? 5.83214   0.02162   7.97511  1.000 17.24373 ? 240 TYR A HD1  1 
ATOM   3396 H  HD2  . TYR A 1 217 ? 7.95612   -1.70208  5.05262  1.000 16.50313 ? 240 TYR A HD2  1 
ATOM   3397 H  HE1  . TYR A 1 217 ? 7.36378   1.73574   8.09625  1.000 18.74018 ? 240 TYR A HE1  1 
ATOM   3398 H  HE2  . TYR A 1 217 ? 9.51738   0.00089   5.18914  1.000 19.43177 ? 240 TYR A HE2  1 
ATOM   3399 H  HH   . TYR A 1 217 ? 10.05889  2.01268   6.10698  1.000 24.03827 ? 240 TYR A HH   1 
ATOM   3400 N  N    . GLY A 1 218 ? 2.45612   -2.60421  4.66267  1.000 11.11015 ? 241 GLY A N    1 
ATOM   3401 C  CA   . GLY A 1 218 ? 1.60739   -3.64845  4.11661  1.000 11.28627 ? 241 GLY A CA   1 
ATOM   3402 C  C    . GLY A 1 218 ? 1.37727   -4.79659  5.06029  1.000 10.79548 ? 241 GLY A C    1 
ATOM   3403 O  O    . GLY A 1 218 ? 1.11133   -5.92813  4.61901  1.000 10.90975 ? 241 GLY A O    1 
ATOM   3404 H  H    . GLY A 1 218 ? 2.09143   -1.82637  4.70227  1.000 13.33218 ? 241 GLY A H    1 
ATOM   3405 H  HA2  . GLY A 1 218 ? 0.74434   -3.26751  3.89092  1.000 13.54352 ? 241 GLY A HA2  1 
ATOM   3406 H  HA3  . GLY A 1 218 ? 2.01805   -3.99948  3.31098  1.000 13.54352 ? 241 GLY A HA3  1 
ATOM   3407 N  N    . THR A 1 219 ? 1.45199   -4.52826  6.35310  1.000 10.47871 ? 242 THR A N    1 
ATOM   3408 C  CA   . THR A 1 219 ? 1.32401   -5.57932  7.35019  1.000 9.72822  ? 242 THR A CA   1 
ATOM   3409 C  C    . THR A 1 219 ? -0.09892  -6.09896  7.33253  1.000 10.36323 ? 242 THR A C    1 
ATOM   3410 O  O    . THR A 1 219 ? -1.05986  -5.32626  7.38008  1.000 10.78776 ? 242 THR A O    1 
ATOM   3411 C  CB   . THR A 1 219 ? 1.75927   -5.06806  8.72234  1.000 10.28846 ? 242 THR A CB   1 
ATOM   3412 O  OG1  . THR A 1 219 ? 3.14410   -4.70839  8.63426  1.000 11.08507 ? 242 THR A OG1  1 
ATOM   3413 C  CG2  . THR A 1 219 ? 1.61221   -6.15527  9.77088  1.000 10.64406 ? 242 THR A CG2  1 
ATOM   3414 H  H    . THR A 1 219 ? 1.57672   -3.74352  6.68208  1.000 12.57445 ? 242 THR A H    1 
ATOM   3415 H  HA   . THR A 1 219 ? 1.90953   -6.32671  7.15150  1.000 11.67387 ? 242 THR A HA   1 
ATOM   3416 H  HB   . THR A 1 219 ? 1.21352   -4.31159  8.98846  1.000 12.34616 ? 242 THR A HB   1 
ATOM   3417 H  HG1  . THR A 1 219 ? 3.22842   -3.99437  8.19990  1.000 13.30208 ? 242 THR A HG1  1 
ATOM   3418 H  HG21 . THR A 1 219 ? 2.00604   -5.86413  10.60816 1.000 12.77288 ? 242 THR A HG21 1 
ATOM   3419 H  HG22 . THR A 1 219 ? 0.67340   -6.35143  9.91598  1.000 12.77288 ? 242 THR A HG22 1 
ATOM   3420 H  HG23 . THR A 1 219 ? 2.06074   -6.96326  9.47616  1.000 12.77288 ? 242 THR A HG23 1 
ATOM   3421 N  N    . THR A 1 220 ? -0.23633  -7.42179  7.23323  1.000 9.52080  ? 243 THR A N    1 
ATOM   3422 C  CA   . THR A 1 220 ? -1.53030  -8.06892  7.03616  1.000 9.30817  ? 243 THR A CA   1 
ATOM   3423 C  C    . THR A 1 220 ? -1.48048  -9.32833  7.88813  1.000 8.72132  ? 243 THR A C    1 
ATOM   3424 O  O    . THR A 1 220 ? -0.68019  -10.22350 7.60027  1.000 9.10000  ? 243 THR A O    1 
ATOM   3425 C  CB   . THR A 1 220 ? -1.73823  -8.42099  5.56167  1.000 11.14351 ? 243 THR A CB   1 
ATOM   3426 O  OG1  . THR A 1 220 ? -1.40279  -7.30933  4.71532  1.000 11.38427 ? 243 THR A OG1  1 
ATOM   3427 C  CG2  . THR A 1 220 ? -3.18690  -8.79116  5.31216  1.000 11.95516 ? 243 THR A CG2  1 
ATOM   3428 H  H    . THR A 1 220 ? 0.41995   -7.97576  7.27806  1.000 11.42496 ? 243 THR A H    1 
ATOM   3429 H  HA   . THR A 1 220 ? -2.26311  -7.49873  7.31685  1.000 11.16981 ? 243 THR A HA   1 
ATOM   3430 H  HB   . THR A 1 220 ? -1.16485  -9.17160  5.34095  1.000 13.37221 ? 243 THR A HB   1 
ATOM   3431 H  HG1  . THR A 1 220 ? -0.57062  -7.19514  4.70737  1.000 13.66112 ? 243 THR A HG1  1 
ATOM   3432 H  HG21 . THR A 1 220 ? -3.33452  -8.93296  4.36401  1.000 14.34620 ? 243 THR A HG21 1 
ATOM   3433 H  HG22 . THR A 1 220 ? -3.40836  -9.60546  5.79047  1.000 14.34620 ? 243 THR A HG22 1 
ATOM   3434 H  HG23 . THR A 1 220 ? -3.76897  -8.07811  5.61819  1.000 14.34620 ? 243 THR A HG23 1 
ATOM   3435 N  N    . ASN A 1 221 ? -2.33261  -9.39758  8.91932  1.000 8.57378  ? 244 ASN A N    1 
ATOM   3436 C  CA   . ASN A 1 221 ? -2.24968  -10.44224 9.91466  1.000 8.99907  ? 244 ASN A CA   1 
ATOM   3437 C  C    . ASN A 1 221 ? -3.61832  -11.03977 10.20612 1.000 8.43759  ? 244 ASN A C    1 
ATOM   3438 O  O    . ASN A 1 221 ? -4.65219  -10.40777 9.98344  1.000 8.39735  ? 244 ASN A O    1 
ATOM   3439 C  CB   . ASN A 1 221 ? -1.77073  -9.87473  11.25792 1.000 8.86701  ? 244 ASN A CB   1 
ATOM   3440 C  CG   . ASN A 1 221 ? -0.38379  -9.26024  11.20312 1.000 9.21087  ? 244 ASN A CG   1 
ATOM   3441 O  OD1  . ASN A 1 221 ? 0.46030   -9.66165  10.41652 1.000 9.77746  ? 244 ASN A OD1  1 
ATOM   3442 N  ND2  . ASN A 1 221 ? -0.11657  -8.32457  12.11829 1.000 9.85839  ? 244 ASN A ND2  1 
ATOM   3443 H  H    . ASN A 1 221 ? -2.97130  -8.83782  9.05477  1.000 10.28853 ? 244 ASN A H    1 
ATOM   3444 H  HA   . ASN A 1 221 ? -1.65583  -11.12433 9.56395  1.000 10.79888 ? 244 ASN A HA   1 
ATOM   3445 H  HB2  . ASN A 1 221 ? -2.38903  -9.18393  11.54322 1.000 10.64042 ? 244 ASN A HB2  1 
ATOM   3446 H  HB3  . ASN A 1 221 ? -1.75062  -10.59209 11.91052 1.000 10.64042 ? 244 ASN A HB3  1 
ATOM   3447 H  HD21 . ASN A 1 221 ? 0.65457   -7.94410  12.13178 1.000 11.83007 ? 244 ASN A HD21 1 
ATOM   3448 H  HD22 . ASN A 1 221 ? -0.71568  -8.10265  12.69399 1.000 11.83007 ? 244 ASN A HD22 1 
ATOM   3449 N  N    . ASP A 1 222 ? -3.61782  -12.24713 10.76234 1.000 8.23664  ? 245 ASP A N    1 
ATOM   3450 C  CA   . ASP A 1 222 ? -4.85590  -12.84582 11.26320 1.000 8.17860  ? 245 ASP A CA   1 
ATOM   3451 C  C    . ASP A 1 222 ? -4.47780  -13.90369 12.28222 1.000 8.20753  ? 245 ASP A C    1 
ATOM   3452 O  O    . ASP A 1 222 ? -3.46966  -14.58386 12.11527 1.000 8.70251  ? 245 ASP A O    1 
ATOM   3453 C  CB   . ASP A 1 222 ? -5.63432  -13.47715 10.09321 1.000 8.47385  ? 245 ASP A CB   1 
ATOM   3454 C  CG   . ASP A 1 222 ? -7.09849  -13.72780 10.38912 1.000 8.29284  ? 245 ASP A CG   1 
ATOM   3455 O  OD1  . ASP A 1 222 ? -7.64666  -13.23315 11.40809 1.000 9.55193  ? 245 ASP A OD1  1 
ATOM   3456 O  OD2  . ASP A 1 222 ? -7.73741  -14.41772 9.55161  1.000 9.15816  ? 245 ASP A OD2  1 
ATOM   3457 H  H    . ASP A 1 222 ? -2.91915  -12.73862 10.86183 1.000 9.88397  ? 245 ASP A H    1 
ATOM   3458 H  HA   . ASP A 1 222 ? -5.41845  -12.18649 11.69876 1.000 9.81432  ? 245 ASP A HA   1 
ATOM   3459 H  HB2  . ASP A 1 222 ? -5.58625  -12.88065 9.32981  1.000 10.16862 ? 245 ASP A HB2  1 
ATOM   3460 H  HB3  . ASP A 1 222 ? -5.22815  -14.33024 9.87376  1.000 10.16862 ? 245 ASP A HB3  1 
ATOM   3461 N  N    . ILE A 1 223 ? -5.25909  -14.00547 13.34943 1.000 8.00599  ? 246 ILE A N    1 
ATOM   3462 C  CA   . ILE A 1 223 ? -5.10159  -15.06158 14.33645 1.000 7.82323  ? 246 ILE A CA   1 
ATOM   3463 C  C    . ILE A 1 223 ? -6.46939  -15.69859 14.52086 1.000 8.42519  ? 246 ILE A C    1 
ATOM   3464 O  O    . ILE A 1 223 ? -7.47927  -14.99040 14.60651 1.000 9.05266  ? 246 ILE A O    1 
ATOM   3465 C  CB   . ILE A 1 223 ? -4.48291  -14.53636 15.65517 1.000 8.63156  ? 246 ILE A CB   1 
ATOM   3466 C  CG1  . ILE A 1 223 ? -5.41525  -13.66475 16.47869 1.000 9.47150  ? 246 ILE A CG1  1 
ATOM   3467 C  CG2  . ILE A 1 223 ? -3.18161  -13.80616 15.34316 1.000 9.00364  ? 246 ILE A CG2  1 
ATOM   3468 C  CD1  . ILE A 1 223 ? -4.82563  -13.27771 17.85411 1.000 10.08434 ? 246 ILE A CD1  1 
ATOM   3469 H  H    . ILE A 1 223 ? -5.90146  -13.46168 13.52622 1.000 9.60719  ? 246 ILE A H    1 
ATOM   3470 H  HA   . ILE A 1 223 ? -4.49485  -15.74981 14.02165 1.000 9.38787  ? 246 ILE A HA   1 
ATOM   3471 H  HB   . ILE A 1 223 ? -4.31170  -15.31247 16.21127 1.000 10.35788 ? 246 ILE A HB   1 
ATOM   3472 H  HG12 . ILE A 1 223 ? -5.59487  -12.84661 15.98951 1.000 11.36580 ? 246 ILE A HG12 1 
ATOM   3473 H  HG13 . ILE A 1 223 ? -6.24239  -14.14734 16.63312 1.000 11.36580 ? 246 ILE A HG13 1 
ATOM   3474 H  HG21 . ILE A 1 223 ? -2.69042  -13.66960 16.16838 1.000 10.80437 ? 246 ILE A HG21 1 
ATOM   3475 H  HG22 . ILE A 1 223 ? -2.65632  -14.34465 14.73079 1.000 10.80437 ? 246 ILE A HG22 1 
ATOM   3476 H  HG23 . ILE A 1 223 ? -3.38937  -12.95042 14.93640 1.000 10.80437 ? 246 ILE A HG23 1 
ATOM   3477 H  HD11 . ILE A 1 223 ? -5.50067  -12.80442 18.36521 1.000 12.10121 ? 246 ILE A HD11 1 
ATOM   3478 H  HD12 . ILE A 1 223 ? -4.56130  -14.08478 18.32280 1.000 12.10121 ? 246 ILE A HD12 1 
ATOM   3479 H  HD13 . ILE A 1 223 ? -4.05352  -12.70670 17.71734 1.000 12.10121 ? 246 ILE A HD13 1 
ATOM   3480 N  N    . ALA A 1 224 ? -6.50413  -17.02078 14.59932 1.000 8.63661  ? 247 ALA A N    1 
ATOM   3481 C  CA   . ALA A 1 224 ? -7.78548  -17.69930 14.55980 1.000 9.16558  ? 247 ALA A CA   1 
ATOM   3482 C  C    . ALA A 1 224 ? -7.81486  -18.96429 15.39678 1.000 9.43892  ? 247 ALA A C    1 
ATOM   3483 O  O    . ALA A 1 224 ? -6.81839  -19.67626 15.51498 1.000 9.76444  ? 247 ALA A O    1 
ATOM   3484 C  CB   . ALA A 1 224 ? -8.11586  -18.12582 13.12384 1.000 10.46082 ? 247 ALA A CB   1 
ATOM   3485 H  H    . ALA A 1 224 ? -5.81664  -17.53203 14.67392 1.000 10.36394 ? 247 ALA A H    1 
ATOM   3486 H  HA   . ALA A 1 224 ? -8.43379  -17.08204 14.93341 1.000 10.99869 ? 247 ALA A HA   1 
ATOM   3487 H  HB1  . ALA A 1 224 ? -8.97854  -18.56925 13.11668 1.000 12.55298 ? 247 ALA A HB1  1 
ATOM   3488 H  HB2  . ALA A 1 224 ? -8.14431  -17.33778 12.55897 1.000 12.55298 ? 247 ALA A HB2  1 
ATOM   3489 H  HB3  . ALA A 1 224 ? -7.42878  -18.73384 12.80900 1.000 12.55298 ? 247 ALA A HB3  1 
ATOM   3490 N  N    . VAL A 1 225 ? -8.98332  -19.23318 15.96873 1.000 9.79580  ? 248 VAL A N    1 
ATOM   3491 C  CA   . VAL A 1 225 ? -9.35552  -20.54973 16.47132 1.000 10.26944 ? 248 VAL A CA   1 
ATOM   3492 C  C    . VAL A 1 225 ? -10.33412 -21.13675 15.45853 1.000 9.91497  ? 248 VAL A C    1 
ATOM   3493 O  O    . VAL A 1 225 ? -11.23434 -20.43356 14.96605 1.000 11.48256 ? 248 VAL A O    1 
ATOM   3494 C  CB   . VAL A 1 225 ? -9.90790  -20.49222 17.91058 1.000 12.27563 ? 248 VAL A CB   1 
ATOM   3495 C  CG1  . VAL A 1 225 ? -11.08355 -19.56211 18.03931 1.000 14.91610 ? 248 VAL A CG1  1 
ATOM   3496 C  CG2  . VAL A 1 225 ? -10.27558 -21.87907 18.38250 1.000 12.78144 ? 248 VAL A CG2  1 
ATOM   3497 H  H    . VAL A 1 225 ? -9.60085  -18.64525 16.08098 1.000 11.75496 ? 248 VAL A H    1 
ATOM   3498 H  HA   . VAL A 1 225 ? -8.58445  -21.13634 16.51866 1.000 12.32333 ? 248 VAL A HA   1 
ATOM   3499 H  HB   . VAL A 1 225 ? -9.20828  -20.13670 18.48070 1.000 14.73076 ? 248 VAL A HB   1 
ATOM   3500 H  HG11 . VAL A 1 225 ? -11.40986 -19.59007 18.95235 1.000 17.89932 ? 248 VAL A HG11 1 
ATOM   3501 H  HG12 . VAL A 1 225 ? -10.79966 -18.66164 17.81694 1.000 17.89932 ? 248 VAL A HG12 1 
ATOM   3502 H  HG13 . VAL A 1 225 ? -11.78140 -19.84896 17.42971 1.000 17.89932 ? 248 VAL A HG13 1 
ATOM   3503 H  HG21 . VAL A 1 225 ? -10.61852 -21.82390 19.28817 1.000 15.33773 ? 248 VAL A HG21 1 
ATOM   3504 H  HG22 . VAL A 1 225 ? -10.95455 -22.24347 17.79333 1.000 15.33773 ? 248 VAL A HG22 1 
ATOM   3505 H  HG23 . VAL A 1 225 ? -9.48431  -22.43976 18.36199 1.000 15.33773 ? 248 VAL A HG23 1 
ATOM   3506 N  N    . ILE A 1 226 ? -10.10003 -22.38523 15.06918 1.000 11.05535 ? 249 ILE A N    1 
ATOM   3507 C  CA   . ILE A 1 226 ? -10.78932 -23.00095 13.94386 1.000 11.12652 ? 249 ILE A CA   1 
ATOM   3508 C  C    . ILE A 1 226 ? -11.38776 -24.30816 14.40816 1.000 12.20225 ? 249 ILE A C    1 
ATOM   3509 O  O    . ILE A 1 226 ? -10.68767 -25.13760 15.00296 1.000 12.81670 ? 249 ILE A O    1 
ATOM   3510 C  CB   . ILE A 1 226 ? -9.80255  -23.27364 12.79633 1.000 12.44196 ? 249 ILE A CB   1 
ATOM   3511 C  CG1  . ILE A 1 226 ? -9.17292  -21.98165 12.30593 1.000 12.93447 ? 249 ILE A CG1  1 
ATOM   3512 C  CG2  . ILE A 1 226 ? -10.49582 -24.01543 11.64309 1.000 13.29455 ? 249 ILE A CG2  1 
ATOM   3513 C  CD1  . ILE A 1 226 ? -7.88843  -22.18874 11.55846 1.000 13.19007 ? 249 ILE A CD1  1 
ATOM   3514 H  H    . ILE A 1 226 ? -9.53272  -22.90662 15.45116 1.000 13.26642 ? 249 ILE A H    1 
ATOM   3515 H  HA   . ILE A 1 226 ? -11.50465 -22.42102 13.63908 1.000 13.35183 ? 249 ILE A HA   1 
ATOM   3516 H  HB   . ILE A 1 226 ? -9.09574  -23.84171 13.14073 1.000 14.93036 ? 249 ILE A HB   1 
ATOM   3517 H  HG12 . ILE A 1 226 ? -9.79539  -21.53675 11.70970 1.000 15.52136 ? 249 ILE A HG12 1 
ATOM   3518 H  HG13 . ILE A 1 226 ? -8.98389  -21.41564 13.07066 1.000 15.52136 ? 249 ILE A HG13 1 
ATOM   3519 H  HG21 . ILE A 1 226 ? -9.89427  -24.04997 10.88293 1.000 15.95346 ? 249 ILE A HG21 1 
ATOM   3520 H  HG22 . ILE A 1 226 ? -10.71496 -24.91490 11.93263 1.000 15.95346 ? 249 ILE A HG22 1 
ATOM   3521 H  HG23 . ILE A 1 226 ? -11.30570 -23.53881 11.40262 1.000 15.95346 ? 249 ILE A HG23 1 
ATOM   3522 H  HD11 . ILE A 1 226 ? -7.48520  -21.32514 11.37817 1.000 15.82808 ? 249 ILE A HD11 1 
ATOM   3523 H  HD12 . ILE A 1 226 ? -7.29043  -22.72621 12.10106 1.000 15.82808 ? 249 ILE A HD12 1 
ATOM   3524 H  HD13 . ILE A 1 226 ? -8.07865  -22.64562 10.72421 1.000 15.82808 ? 249 ILE A HD13 1 
ATOM   3525 N  N    . TRP A 1 227 ? -12.65374 -24.52970 14.07744 1.000 13.57260 ? 250 TRP A N    1 
ATOM   3526 C  CA   . TRP A 1 227 ? -13.27912 -25.82531 14.30983 1.000 16.10874 ? 250 TRP A CA   1 
ATOM   3527 C  C    . TRP A 1 227 ? -13.53087 -26.48963 12.96916 1.000 16.13432 ? 250 TRP A C    1 
ATOM   3528 O  O    . TRP A 1 227 ? -14.52456 -26.17301 12.29632 1.000 16.80753 ? 250 TRP A O    1 
ATOM   3529 C  CB   . TRP A 1 227 ? -14.58803 -25.65949 15.08026 1.000 19.21533 ? 250 TRP A CB   1 
ATOM   3530 C  CG   . TRP A 1 227 ? -14.35061 -25.28490 16.49133 1.000 22.95884 ? 250 TRP A CG   1 
ATOM   3531 C  CD1  . TRP A 1 227 ? -14.23355 -26.12884 17.55259 1.000 25.86488 ? 250 TRP A CD1  1 
ATOM   3532 C  CD2  . TRP A 1 227 ? -14.20596 -23.96307 17.00665 1.000 24.40390 ? 250 TRP A CD2  1 
ATOM   3533 N  NE1  . TRP A 1 227 ? -14.01564 -25.40862 18.70976 1.000 27.89327 ? 250 TRP A NE1  1 
ATOM   3534 C  CE2  . TRP A 1 227 ? -13.99142 -24.07420 18.39357 1.000 26.54504 ? 250 TRP A CE2  1 
ATOM   3535 C  CE3  . TRP A 1 227 ? -14.22627 -22.69326 16.42654 1.000 24.39647 ? 250 TRP A CE3  1 
ATOM   3536 C  CZ2  . TRP A 1 227 ? -13.81046 -22.96419 19.20083 1.000 25.90359 ? 250 TRP A CZ2  1 
ATOM   3537 C  CZ3  . TRP A 1 227 ? -14.05122 -21.60099 17.22990 1.000 25.40971 ? 250 TRP A CZ3  1 
ATOM   3538 C  CH2  . TRP A 1 227 ? -13.84828 -21.73964 18.60361 1.000 25.99371 ? 250 TRP A CH2  1 
ATOM   3539 H  H    . TRP A 1 227 ? -13.17154 -23.94530 13.71695 1.000 16.28712 ? 250 TRP A H    1 
ATOM   3540 H  HA   . TRP A 1 227 ? -12.68723 -26.38626 14.83508 1.000 19.33048 ? 250 TRP A HA   1 
ATOM   3541 H  HB2  . TRP A 1 227 ? -15.11710 -24.96069 14.66473 1.000 23.05839 ? 250 TRP A HB2  1 
ATOM   3542 H  HB3  . TRP A 1 227 ? -15.07574 -26.49784 15.06583 1.000 23.05839 ? 250 TRP A HB3  1 
ATOM   3543 H  HD1  . TRP A 1 227 ? -14.29189 -27.05579 17.50506 1.000 31.03786 ? 250 TRP A HD1  1 
ATOM   3544 H  HE1  . TRP A 1 227 ? -13.91245 -25.74062 19.49636 1.000 33.47192 ? 250 TRP A HE1  1 
ATOM   3545 H  HE3  . TRP A 1 227 ? -14.35637 -22.59240 15.51123 1.000 29.27576 ? 250 TRP A HE3  1 
ATOM   3546 H  HZ2  . TRP A 1 227 ? -13.66849 -23.05079 20.11584 1.000 31.08431 ? 250 TRP A HZ2  1 
ATOM   3547 H  HZ3  . TRP A 1 227 ? -14.06768 -20.75040 16.85423 1.000 30.49165 ? 250 TRP A HZ3  1 
ATOM   3548 H  HH2  . TRP A 1 227 ? -13.73605 -20.97747 19.12456 1.000 31.19245 ? 250 TRP A HH2  1 
ATOM   3549 N  N    . PRO A 1 228 ? -12.65673 -27.38224 12.51873 1.000 16.11414 ? 251 PRO A N    1 
ATOM   3550 C  CA   . PRO A 1 228 ? -12.89803 -28.06247 11.24442 1.000 18.19642 ? 251 PRO A CA   1 
ATOM   3551 C  C    . PRO A 1 228 ? -14.02074 -29.07092 11.40364 1.000 19.94745 ? 251 PRO A C    1 
ATOM   3552 O  O    . PRO A 1 228 ? -14.33427 -29.52706 12.50249 1.000 20.41703 ? 251 PRO A O    1 
ATOM   3553 C  CB   . PRO A 1 228 ? -11.56653 -28.77341 10.95333 1.000 18.18034 ? 251 PRO A CB   1 
ATOM   3554 C  CG   . PRO A 1 228 ? -10.59815 -28.28459 11.95698 1.000 17.54922 ? 251 PRO A CG   1 
ATOM   3555 C  CD   . PRO A 1 228 ? -11.40599 -27.83665 13.14281 1.000 16.05431 ? 251 PRO A CD   1 
ATOM   3556 H  HA   . PRO A 1 228 ? -13.09065 -27.43354 10.53151 1.000 21.83570 ? 251 PRO A HA   1 
ATOM   3557 H  HB2  . PRO A 1 228 ? -11.68733 -29.73243 11.03455 1.000 21.81641 ? 251 PRO A HB2  1 
ATOM   3558 H  HB3  . PRO A 1 228 ? -11.27031 -28.55109 10.05682 1.000 21.81641 ? 251 PRO A HB3  1 
ATOM   3559 H  HG2  . PRO A 1 228 ? -9.99669  -29.00389 12.20547 1.000 21.05906 ? 251 PRO A HG2  1 
ATOM   3560 H  HG3  . PRO A 1 228 ? -10.09369 -27.54300 11.58755 1.000 21.05906 ? 251 PRO A HG3  1 
ATOM   3561 H  HD2  . PRO A 1 228 ? -11.56817 -28.57337 13.75259 1.000 19.26517 ? 251 PRO A HD2  1 
ATOM   3562 H  HD3  . PRO A 1 228 ? -10.96547 -27.10984 13.61034 1.000 19.26517 ? 251 PRO A HD3  1 
ATOM   3563 N  N    . LYS A 1 229 ? -14.63904 -29.40803 10.28952 1.000 21.74294 ? 252 LYS A N    1 
ATOM   3564 C  CA   . LYS A 1 229 ? -15.70221 -30.39873 10.34167 1.000 24.80503 ? 252 LYS A CA   1 
ATOM   3565 C  C    . LYS A 1 229 ? -15.15244 -31.71728 10.87447 1.000 25.49045 ? 252 LYS A C    1 
ATOM   3566 O  O    . LYS A 1 229 ? -14.16978 -32.25049 10.34721 1.000 25.27070 ? 252 LYS A O    1 
ATOM   3567 C  CB   . LYS A 1 229 ? -16.30419 -30.59006 8.95214  1.000 29.80210 ? 252 LYS A CB   1 
ATOM   3568 C  CG   . LYS A 1 229 ? -17.55452 -31.47071 8.95794  1.000 34.41965 ? 252 LYS A CG   1 
ATOM   3569 C  CD   . LYS A 1 229 ? -18.24812 -31.48080 7.61256  1.000 39.98352 ? 252 LYS A CD   1 
ATOM   3570 C  CE   . LYS A 1 229 ? -19.47327 -32.38545 7.64950  1.000 44.75748 ? 252 LYS A CE   1 
ATOM   3571 N  NZ   . LYS A 1 229 ? -20.04241 -32.61985 6.29595  1.000 48.31685 ? 252 LYS A NZ   1 
ATOM   3572 H  H    . LYS A 1 229 ? -14.46917 -29.08852 9.50936  1.000 26.09153 ? 252 LYS A H    1 
ATOM   3573 H  HA   . LYS A 1 229 ? -16.40605 -30.09262 10.93480 1.000 29.76604 ? 252 LYS A HA   1 
ATOM   3574 H  HB2  . LYS A 1 229 ? -16.55055 -29.72296 8.59388  1.000 35.76252 ? 252 LYS A HB2  1 
ATOM   3575 H  HB3  . LYS A 1 229 ? -15.64455 -31.01071 8.37869  1.000 35.76252 ? 252 LYS A HB3  1 
ATOM   3576 H  HG2  . LYS A 1 229 ? -17.30234 -32.38180 9.17524  1.000 41.30358 ? 252 LYS A HG2  1 
ATOM   3577 H  HG3  . LYS A 1 229 ? -18.17978 -31.13309 9.61822  1.000 41.30358 ? 252 LYS A HG3  1 
ATOM   3578 H  HD2  . LYS A 1 229 ? -18.53470 -30.58173 7.38796  1.000 47.98023 ? 252 LYS A HD2  1 
ATOM   3579 H  HD3  . LYS A 1 229 ? -17.63869 -31.81366 6.93528  1.000 47.98023 ? 252 LYS A HD3  1 
ATOM   3580 H  HE2  . LYS A 1 229 ? -19.22325 -33.24437 8.02452  1.000 53.70898 ? 252 LYS A HE2  1 
ATOM   3581 H  HE3  . LYS A 1 229 ? -20.15827 -31.97105 8.19717  1.000 53.70898 ? 252 LYS A HE3  1 
ATOM   3582 H  HZ1  . LYS A 1 229 ? -20.73904 -33.17112 6.34995  1.000 57.98022 ? 252 LYS A HZ1  1 
ATOM   3583 H  HZ2  . LYS A 1 229 ? -20.31083 -31.84912 5.94095  1.000 57.98022 ? 252 LYS A HZ2  1 
ATOM   3584 H  HZ3  . LYS A 1 229 ? -19.42691 -32.98327 5.76569  1.000 57.98022 ? 252 LYS A HZ3  1 
ATOM   3585 N  N    . ASP A 1 230 ? -15.76497 -32.20972 11.95353 1.000 26.47314 ? 253 ASP A N    1 
ATOM   3586 C  CA   . ASP A 1 230 ? -15.48362 -33.52880 12.51558 1.000 27.82395 ? 253 ASP A CA   1 
ATOM   3587 C  C    . ASP A 1 230 ? -14.03479 -33.70252 12.95160 1.000 26.23968 ? 253 ASP A C    1 
ATOM   3588 O  O    . ASP A 1 230 ? -13.49500 -34.80945 12.90916 1.000 27.83085 ? 253 ASP A O    1 
ATOM   3589 C  CB   . ASP A 1 230 ? -15.89900 -34.63516 11.54301 1.000 29.60339 ? 253 ASP A CB   1 
ATOM   3590 C  CG   . ASP A 1 230 ? -17.40950 -34.75904 11.41421 1.000 33.72327 ? 253 ASP A CG   1 
ATOM   3591 O  OD1  . ASP A 1 230 ? -18.10337 -34.73134 12.45459 1.000 35.73896 ? 253 ASP A OD1  1 
ATOM   3592 O  OD2  . ASP A 1 230 ? -17.90241 -34.87727 10.27627 1.000 36.07672 ? 253 ASP A OD2  1 
ATOM   3593 H  H    . ASP A 1 230 ? -16.36862 -31.78203 12.39204 1.000 31.76776 ? 253 ASP A H    1 
ATOM   3594 H  HA   . ASP A 1 230 ? -16.01138 -33.61814 13.32453 1.000 33.38873 ? 253 ASP A HA   1 
ATOM   3595 H  HB2  . ASP A 1 230 ? -15.53705 -34.43797 10.66494 1.000 35.52407 ? 253 ASP A HB2  1 
ATOM   3596 H  HB3  . ASP A 1 230 ? -15.55331 -35.48368 11.86145 1.000 35.52407 ? 253 ASP A HB3  1 
ATOM   3597 N  N    A ARG A 1 231 ? -13.40036 -32.62034 13.39431 0.543 24.35850 ? 254 ARG A N    1 
ATOM   3598 N  N    B ARG A 1 231 ? -13.39736 -32.61945 13.38965 0.457 24.66339 ? 254 ARG A N    1 
ATOM   3599 C  CA   A ARG A 1 231 ? -12.02152 -32.67351 13.85038 0.543 23.85058 ? 254 ARG A CA   1 
ATOM   3600 C  CA   B ARG A 1 231 ? -12.01587 -32.66961 13.84036 0.457 24.23529 ? 254 ARG A CA   1 
ATOM   3601 C  C    A ARG A 1 231 ? -11.86290 -31.79622 15.08464 0.543 20.39836 ? 254 ARG A C    1 
ATOM   3602 C  C    B ARG A 1 231 ? -11.85745 -31.79176 15.07564 0.457 20.98911 ? 254 ARG A C    1 
ATOM   3603 O  O    A ARG A 1 231 ? -12.66634 -30.89625 15.34333 0.543 21.03517 ? 254 ARG A O    1 
ATOM   3604 O  O    B ARG A 1 231 ? -12.65652 -30.88594 15.32709 0.457 21.41441 ? 254 ARG A O    1 
ATOM   3605 C  CB   A ARG A 1 231 ? -11.04899 -32.19743 12.75994 0.543 27.01970 ? 254 ARG A CB   1 
ATOM   3606 C  CB   B ARG A 1 231 ? -11.04827 -32.18798 12.74575 0.457 27.27135 ? 254 ARG A CB   1 
ATOM   3607 C  CG   A ARG A 1 231 ? -11.00470 -33.07649 11.51577 0.543 30.40818 ? 254 ARG A CG   1 
ATOM   3608 C  CG   B ARG A 1 231 ? -11.06600 -33.00624 11.45457 0.457 30.88328 ? 254 ARG A CG   1 
ATOM   3609 C  CD   A ARG A 1 231 ? -10.30437 -34.41292 11.78055 0.543 34.10813 ? 254 ARG A CD   1 
ATOM   3610 C  CD   B ARG A 1 231 ? -10.48497 -34.40420 11.65823 0.457 34.71714 ? 254 ARG A CD   1 
ATOM   3611 N  NE   A ARG A 1 231 ? -10.17077 -35.20306 10.56129 0.543 36.35315 ? 254 ARG A NE   1 
ATOM   3612 N  NE   B ARG A 1 231 ? -9.43383  -34.71759 10.69487 0.457 37.13004 ? 254 ARG A NE   1 
ATOM   3613 C  CZ   A ARG A 1 231 ? -10.94177 -36.23401 10.23708 0.543 37.96766 ? 254 ARG A CZ   1 
ATOM   3614 C  CZ   B ARG A 1 231 ? -8.16432  -34.35345 10.82405 0.457 39.41197 ? 254 ARG A CZ   1 
ATOM   3615 N  NH1  A ARG A 1 231 ? -11.88714 -36.67611 11.05034 0.543 38.37326 ? 254 ARG A NH1  1 
ATOM   3616 N  NH1  B ARG A 1 231 ? -7.75378  -33.63100 11.85437 0.457 40.27687 ? 254 ARG A NH1  1 
ATOM   3617 N  NH2  A ARG A 1 231 ? -10.75802 -36.83709 9.06584  0.543 39.14970 ? 254 ARG A NH2  1 
ATOM   3618 N  NH2  B ARG A 1 231 ? -7.28596  -34.72087 9.89497  0.457 40.14172 ? 254 ARG A NH2  1 
ATOM   3619 H  H    A ARG A 1 231 ? -13.75352 -31.83750 13.43936 0.543 29.23020 ? 254 ARG A H    1 
ATOM   3620 H  H    B ARG A 1 231 ? -13.75046 -31.83657 13.43463 0.457 29.59607 ? 254 ARG A H    1 
ATOM   3621 H  HA   A ARG A 1 231 ? -11.80333 -33.58776 14.09007 0.543 28.62069 ? 254 ARG A HA   1 
ATOM   3622 H  HA   B ARG A 1 231 ? -11.79266 -33.58327 14.07763 0.457 29.08235 ? 254 ARG A HA   1 
ATOM   3623 H  HB2  A ARG A 1 231 ? -11.31315 -31.30734 12.47910 0.543 32.42364 ? 254 ARG A HB2  1 
ATOM   3624 H  HB2  B ARG A 1 231 ? -11.27892 -31.27488 12.51346 0.457 32.72562 ? 254 ARG A HB2  1 
ATOM   3625 H  HB3  A ARG A 1 231 ? -10.15417 -32.17547 13.13373 0.543 32.42364 ? 254 ARG A HB3  1 
ATOM   3626 H  HB3  B ARG A 1 231 ? -10.14535 -32.22260 13.09850 0.457 32.72562 ? 254 ARG A HB3  1 
ATOM   3627 H  HG2  A ARG A 1 231 ? -11.91086 -33.26241 11.22386 0.543 36.48981 ? 254 ARG A HG2  1 
ATOM   3628 H  HG2  B ARG A 1 231 ? -11.98147 -33.10010 11.14797 0.457 37.05993 ? 254 ARG A HG2  1 
ATOM   3629 H  HG3  A ARG A 1 231 ? -10.51880 -32.61389 10.81520 0.543 36.48981 ? 254 ARG A HG3  1 
ATOM   3630 H  HG3  B ARG A 1 231 ? -10.53544 -32.55253 10.78111 0.457 37.05993 ? 254 ARG A HG3  1 
ATOM   3631 H  HD2  A ARG A 1 231 ? -9.41641  -34.24491 12.13297 0.543 40.92975 ? 254 ARG A HD2  1 
ATOM   3632 H  HD2  B ARG A 1 231 ? -10.10449 -34.46312 12.54855 0.457 41.66057 ? 254 ARG A HD2  1 
ATOM   3633 H  HD3  A ARG A 1 231 ? -10.82352 -34.92546 12.41983 0.543 40.92975 ? 254 ARG A HD3  1 
ATOM   3634 H  HD3  B ARG A 1 231 ? -11.19237 -35.05991 11.55570 0.457 41.66057 ? 254 ARG A HD3  1 
ATOM   3635 H  HE   A ARG A 1 231 ? -9.54622  -34.98474 10.01186 0.543 43.62378 ? 254 ARG A HE   1 
ATOM   3636 H  HE   B ARG A 1 231 ? -9.65220  -35.16889 9.99612  0.457 44.55604 ? 254 ARG A HE   1 
ATOM   3637 H  HH11 A ARG A 1 231 ? -12.01410 -36.29379 11.81015 0.543 46.04792 ? 254 ARG A HH11 1 
ATOM   3638 H  HH11 B ARG A 1 231 ? -8.31446  -33.38700 12.45911 0.457 48.33225 ? 254 ARG A HH11 1 
ATOM   3639 H  HH12 A ARG A 1 231 ? -12.37467 -37.34578 10.81915 0.543 46.04792 ? 254 ARG A HH12 1 
ATOM   3640 H  HH12 B ARG A 1 231 ? -6.92637  -33.40560 11.91906 0.457 48.33225 ? 254 ARG A HH12 1 
ATOM   3641 H  HH21 A ARG A 1 231 ? -10.14605 -36.55812 8.52987  0.543 46.97964 ? 254 ARG A HH21 1 
ATOM   3642 H  HH21 B ARG A 1 231 ? -7.54345  -35.18874 9.22087  0.457 48.17006 ? 254 ARG A HH21 1 
ATOM   3643 H  HH22 A ARG A 1 231 ? -11.25118 -37.50599 8.84456  0.543 46.97964 ? 254 ARG A HH22 1 
ATOM   3644 H  HH22 B ARG A 1 231 ? -6.46064  -34.49054 9.96843  0.457 48.17006 ? 254 ARG A HH22 1 
ATOM   3645 N  N    . ALA A 1 232 ? -10.80893 -32.06825 15.84805 1.000 19.85801 ? 255 ALA A N    1 
ATOM   3646 C  CA   . ALA A 1 232 ? -10.47802 -31.22433 16.97623 1.000 17.19719 ? 255 ALA A CA   1 
ATOM   3647 C  C    . ALA A 1 232 ? -10.05663 -29.84018 16.49224 1.000 14.73136 ? 255 ALA A C    1 
ATOM   3648 O  O    . ALA A 1 232 ? -9.64187  -29.66899 15.34149 1.000 15.79279 ? 255 ALA A O    1 
ATOM   3649 C  CB   . ALA A 1 232 ? -9.34245  -31.84355 17.78136 1.000 17.80250 ? 255 ALA A CB   1 
ATOM   3650 H  H    . ALA A 1 232 ? -10.27692 -32.73334 15.72881 1.000 23.82961 ? 255 ALA A H    1 
ATOM   3651 H  HA   . ALA A 1 232 ? -11.25381 -31.13337 17.55137 1.000 20.63663 ? 255 ALA A HA   1 
ATOM   3652 H  HB1  . ALA A 1 232 ? -9.04575  -31.20677 18.45022 1.000 21.36300 ? 255 ALA A HB1  1 
ATOM   3653 H  HB2  . ALA A 1 232 ? -9.66459  -32.65043 18.21272 1.000 21.36300 ? 255 ALA A HB2  1 
ATOM   3654 H  HB3  . ALA A 1 232 ? -8.61088  -32.05851 17.18179 1.000 21.36300 ? 255 ALA A HB3  1 
ATOM   3655 N  N    A PRO A 1 233 ? -10.14196 -28.83523 17.35430 0.526 14.34615 ? 256 PRO A N    1 
ATOM   3656 N  N    B PRO A 1 233 ? -10.17034 -28.83250 17.35260 0.474 14.03347 ? 256 PRO A N    1 
ATOM   3657 C  CA   A PRO A 1 233 ? -9.86765  -27.47204 16.89771 0.526 13.67278 ? 256 PRO A CA   1 
ATOM   3658 C  CA   B PRO A 1 233 ? -9.85622  -27.46977 16.92192 0.474 13.39472 ? 256 PRO A CA   1 
ATOM   3659 C  C    A PRO A 1 233 ? -8.40084  -27.23526 16.57884 0.526 12.51666 ? 256 PRO A C    1 
ATOM   3660 C  C    B PRO A 1 233 ? -8.40590  -27.29238 16.50358 0.474 12.82810 ? 256 PRO A C    1 
ATOM   3661 O  O    A PRO A 1 233 ? -7.48927  -27.89478 17.09433 0.526 12.06361 ? 256 PRO A O    1 
ATOM   3662 O  O    B PRO A 1 233 ? -7.51609  -28.07778 16.84136 0.474 13.54980 ? 256 PRO A O    1 
ATOM   3663 C  CB   A PRO A 1 233 ? -10.33720 -26.59074 18.06487 0.526 15.52787 ? 256 PRO A CB   1 
ATOM   3664 C  CB   B PRO A 1 233 ? -10.18373 -26.62662 18.16477 0.474 14.66631 ? 256 PRO A CB   1 
ATOM   3665 C  CG   A PRO A 1 233 ? -10.42851 -27.47983 19.23173 0.526 16.50576 ? 256 PRO A CG   1 
ATOM   3666 C  CG   B PRO A 1 233 ? -11.24963 -27.39273 18.85725 0.474 15.52751 ? 256 PRO A CG   1 
ATOM   3667 C  CD   A PRO A 1 233 ? -10.69859 -28.85648 18.72293 0.526 15.75014 ? 256 PRO A CD   1 
ATOM   3668 C  CD   B PRO A 1 233 ? -10.85622 -28.83521 18.66266 0.474 15.11837 ? 256 PRO A CD   1 
ATOM   3669 H  HA   A PRO A 1 233 ? -10.39497 -27.27929 16.10670 0.526 16.40734 ? 256 PRO A HA   1 
ATOM   3670 H  HA   B PRO A 1 233 ? -10.42599 -27.21907 16.17800 0.474 16.07367 ? 256 PRO A HA   1 
ATOM   3671 H  HB2  A PRO A 1 233 ? -9.69088  -25.88444 18.22083 0.526 18.63344 ? 256 PRO A HB2  1 
ATOM   3672 H  HB2  B PRO A 1 233 ? -9.39638  -26.53883 18.72448 0.474 17.59958 ? 256 PRO A HB2  1 
ATOM   3673 H  HB3  A PRO A 1 233 ? -11.20353 -26.20754 17.85626 0.526 18.63344 ? 256 PRO A HB3  1 
ATOM   3674 H  HB3  B PRO A 1 233 ? -10.50062 -25.74951 17.89802 0.474 17.59958 ? 256 PRO A HB3  1 
ATOM   3675 H  HG2  A PRO A 1 233 ? -9.58966  -27.45792 19.71832 0.526 19.80691 ? 256 PRO A HG2  1 
ATOM   3676 H  HG2  B PRO A 1 233 ? -11.26979 -27.16004 19.79871 0.474 18.63301 ? 256 PRO A HG2  1 
ATOM   3677 H  HG3  A PRO A 1 233 ? -11.15252 -27.18341 19.80518 0.526 19.80691 ? 256 PRO A HG3  1 
ATOM   3678 H  HG3  B PRO A 1 233 ? -12.11093 -27.20768 18.45126 0.474 18.63301 ? 256 PRO A HG3  1 
ATOM   3679 H  HD2  A PRO A 1 233 ? -10.24695 -29.51969 19.26798 0.526 18.90017 ? 256 PRO A HD2  1 
ATOM   3680 H  HD2  B PRO A 1 233 ? -10.25459 -29.12597 19.36580 0.474 18.14204 ? 256 PRO A HD2  1 
ATOM   3681 H  HD3  A PRO A 1 233 ? -11.65170 -29.03573 18.70418 0.526 18.90017 ? 256 PRO A HD3  1 
ATOM   3682 H  HD3  B PRO A 1 233 ? -11.64020 -29.40594 18.63978 0.474 18.14204 ? 256 PRO A HD3  1 
ATOM   3683 N  N    . LEU A 1 234 ? -8.19344  -26.24350 15.71437 1.000 11.94512 ? 257 LEU A N    1 
ATOM   3684 C  CA   . LEU A 1 234 ? -6.87540  -25.75311 15.36402 1.000 11.41683 ? 257 LEU A CA   1 
ATOM   3685 C  C    . LEU A 1 234 ? -6.73077  -24.32363 15.86102 1.000 10.90538 ? 257 LEU A C    1 
ATOM   3686 O  O    . LEU A 1 234 ? -7.71619  -23.59301 16.00540 1.000 11.62168 ? 257 LEU A O    1 
ATOM   3687 C  CB   . LEU A 1 234 ? -6.68408  -25.74278 13.84562 1.000 12.38883 ? 257 LEU A CB   1 
ATOM   3688 C  CG   . LEU A 1 234 ? -7.10140  -27.00641 13.09642 1.000 14.13789 ? 257 LEU A CG   1 
ATOM   3689 C  CD1  . LEU A 1 234 ? -7.03412  -26.72421 11.59158 1.000 16.35408 ? 257 LEU A CD1  1 
ATOM   3690 C  CD2  . LEU A 1 234 ? -6.23764  -28.17252 13.45683 1.000 14.81324 ? 257 LEU A CD2  1 
ATOM   3691 H  H    . LEU A 1 234 ? -8.82507  -25.82688 15.30563 1.000 14.33414 ? 257 LEU A H    1 
ATOM   3692 H  HA   . LEU A 1 234 ? -6.19886  -26.31615 15.77166 1.000 13.70020 ? 257 LEU A HA   1 
ATOM   3693 H  HB2  . LEU A 1 234 ? -7.20633  -25.01061 13.48218 1.000 14.86659 ? 257 LEU A HB2  1 
ATOM   3694 H  HB3  . LEU A 1 234 ? -5.74207  -25.60119 13.66266 1.000 14.86659 ? 257 LEU A HB3  1 
ATOM   3695 H  HG   . LEU A 1 234 ? -8.00741  -27.24878 13.34401 1.000 16.96547 ? 257 LEU A HG   1 
ATOM   3696 H  HD11 . LEU A 1 234 ? -7.37462  -27.49448 11.11029 1.000 19.62489 ? 257 LEU A HD11 1 
ATOM   3697 H  HD12 . LEU A 1 234 ? -7.57485  -25.94400 11.39210 1.000 19.62489 ? 257 LEU A HD12 1 
ATOM   3698 H  HD13 . LEU A 1 234 ? -6.11131  -26.55969 11.34207 1.000 19.62489 ? 257 LEU A HD13 1 
ATOM   3699 H  HD21 . LEU A 1 234 ? -6.61640  -28.97749 13.07023 1.000 17.77588 ? 257 LEU A HD21 1 
ATOM   3700 H  HD22 . LEU A 1 234 ? -5.34548  -28.02511 13.10580 1.000 17.77588 ? 257 LEU A HD22 1 
ATOM   3701 H  HD23 . LEU A 1 234 ? -6.20377  -28.25380 14.42282 1.000 17.77588 ? 257 LEU A HD23 1 
ATOM   3702 N  N    . ILE A 1 235 ? -5.49202  -23.92768 16.09235 1.000 10.28066 ? 258 ILE A N    1 
ATOM   3703 C  CA   . ILE A 1 235 ? -5.13102  -22.53175 16.28225 1.000 9.83625  ? 258 ILE A CA   1 
ATOM   3704 C  C    . ILE A 1 235 ? -4.17242  -22.15887 15.16872 1.000 9.54686  ? 258 ILE A C    1 
ATOM   3705 O  O    . ILE A 1 235 ? -3.22336  -22.89746 14.89595 1.000 10.48607 ? 258 ILE A O    1 
ATOM   3706 C  CB   . ILE A 1 235 ? -4.47264  -22.30377 17.65443 1.000 10.46509 ? 258 ILE A CB   1 
ATOM   3707 C  CG1  . ILE A 1 235 ? -5.45472  -22.62937 18.77704 1.000 12.12909 ? 258 ILE A CG1  1 
ATOM   3708 C  CG2  . ILE A 1 235 ? -3.94361  -20.87033 17.75334 1.000 11.10958 ? 258 ILE A CG2  1 
ATOM   3709 C  CD1  . ILE A 1 235 ? -6.51886  -21.60247 19.02875 1.000 13.50797 ? 258 ILE A CD1  1 
ATOM   3710 H  H    . ILE A 1 235 ? -4.82207  -24.46427 16.14566 1.000 12.33679 ? 258 ILE A H    1 
ATOM   3711 H  HA   . ILE A 1 235 ? -5.92234  -21.97374 16.22451 1.000 11.80350 ? 258 ILE A HA   1 
ATOM   3712 H  HB   . ILE A 1 235 ? -3.71716  -22.90498 17.74778 1.000 12.55811 ? 258 ILE A HB   1 
ATOM   3713 H  HG12 . ILE A 1 235 ? -5.90346  -23.46075 18.55718 1.000 14.55491 ? 258 ILE A HG12 1 
ATOM   3714 H  HG13 . ILE A 1 235 ? -4.95255  -22.73115 19.60067 1.000 14.55491 ? 258 ILE A HG13 1 
ATOM   3715 H  HG21 . ILE A 1 235 ? -3.75168  -20.66794 18.68237 1.000 13.33149 ? 258 ILE A HG21 1 
ATOM   3716 H  HG22 . ILE A 1 235 ? -3.13400  -20.79530 17.22437 1.000 13.33149 ? 258 ILE A HG22 1 
ATOM   3717 H  HG23 . ILE A 1 235 ? -4.61780  -20.26080 17.41447 1.000 13.33149 ? 258 ILE A HG23 1 
ATOM   3718 H  HD11 . ILE A 1 235 ? -7.12893  -21.93880 19.70373 1.000 16.20957 ? 258 ILE A HD11 1 
ATOM   3719 H  HD12 . ILE A 1 235 ? -6.10083  -20.78402 19.33905 1.000 16.20957 ? 258 ILE A HD12 1 
ATOM   3720 H  HD13 . ILE A 1 235 ? -6.99889  -21.43605 18.20245 1.000 16.20957 ? 258 ILE A HD13 1 
ATOM   3721 N  N    . LEU A 1 236 ? -4.42887  -21.04165 14.50230 1.000 9.31263  ? 259 LEU A N    1 
ATOM   3722 C  CA   . LEU A 1 236 ? -3.57076  -20.59996 13.41934 1.000 9.32436  ? 259 LEU A CA   1 
ATOM   3723 C  C    . LEU A 1 236 ? -3.27879  -19.11202 13.53642 1.000 9.13465  ? 259 LEU A C    1 
ATOM   3724 O  O    . LEU A 1 236 ? -4.19831  -18.29442 13.62543 1.000 9.28767  ? 259 LEU A O    1 
ATOM   3725 C  CB   . LEU A 1 236 ? -4.24055  -20.88243 12.07436 1.000 10.02591 ? 259 LEU A CB   1 
ATOM   3726 C  CG   . LEU A 1 236 ? -3.45344  -20.46314 10.83468 1.000 9.47708  ? 259 LEU A CG   1 
ATOM   3727 C  CD1  . LEU A 1 236 ? -2.06222  -21.10308 10.77056 1.000 10.90745 ? 259 LEU A CD1  1 
ATOM   3728 C  CD2  . LEU A 1 236 ? -4.26241  -20.77361 9.56985  1.000 11.18024 ? 259 LEU A CD2  1 
ATOM   3729 H  H    . LEU A 1 236 ? -5.09631  -20.52319 14.66143 1.000 11.17515 ? 259 LEU A H    1 
ATOM   3730 H  HA   . LEU A 1 236 ? -2.72271  -21.06722 13.47735 1.000 11.18923 ? 259 LEU A HA   1 
ATOM   3731 H  HB2  . LEU A 1 236 ? -4.39430  -21.83784 12.00764 1.000 12.03109 ? 259 LEU A HB2  1 
ATOM   3732 H  HB3  . LEU A 1 236 ? -5.08627  -20.40794 12.05192 1.000 12.03109 ? 259 LEU A HB3  1 
ATOM   3733 H  HG   . LEU A 1 236 ? -3.30349  -19.50610 10.88456 1.000 11.37250 ? 259 LEU A HG   1 
ATOM   3734 H  HD11 . LEU A 1 236 ? -1.63516  -20.84760 9.93795  1.000 13.08894 ? 259 LEU A HD11 1 
ATOM   3735 H  HD12 . LEU A 1 236 ? -1.53545  -20.78956 11.52231 1.000 13.08894 ? 259 LEU A HD12 1 
ATOM   3736 H  HD13 . LEU A 1 236 ? -2.15610  -22.06764 10.81180 1.000 13.08894 ? 259 LEU A HD13 1 
ATOM   3737 H  HD21 . LEU A 1 236 ? -3.78610  -20.42971 8.79799  1.000 13.41629 ? 259 LEU A HD21 1 
ATOM   3738 H  HD22 . LEU A 1 236 ? -4.36945  -21.73449 9.49137  1.000 13.41629 ? 259 LEU A HD22 1 
ATOM   3739 H  HD23 . LEU A 1 236 ? -5.13157  -20.34848 9.63860  1.000 13.41629 ? 259 LEU A HD23 1 
ATOM   3740 N  N    . VAL A 1 237 ? -1.99548  -18.76427 13.49694 1.000 8.84366  ? 260 VAL A N    1 
ATOM   3741 C  CA   . VAL A 1 237 ? -1.53346  -17.38854 13.38461 1.000 8.28520  ? 260 VAL A CA   1 
ATOM   3742 C  C    . VAL A 1 237 ? -0.82719  -17.25949 12.04676 1.000 8.48198  ? 260 VAL A C    1 
ATOM   3743 O  O    . VAL A 1 237 ? 0.07055   -18.05464 11.73085 1.000 9.49064  ? 260 VAL A O    1 
ATOM   3744 C  CB   . VAL A 1 237 ? -0.58141  -17.02418 14.53802 1.000 10.32582 ? 260 VAL A CB   1 
ATOM   3745 C  CG1  . VAL A 1 237 ? 0.10162   -15.68648 14.27453 1.000 10.93637 ? 260 VAL A CG1  1 
ATOM   3746 C  CG2  . VAL A 1 237 ? -1.36818  -17.08555 15.86225 1.000 10.88782 ? 260 VAL A CG2  1 
ATOM   3747 H  H    . VAL A 1 237 ? -1.35062  -19.33197 13.53536 1.000 10.61239 ? 260 VAL A H    1 
ATOM   3748 H  HA   . VAL A 1 237 ? -2.28895  -16.78062 13.40856 1.000 9.94225  ? 260 VAL A HA   1 
ATOM   3749 H  HB   . VAL A 1 237 ? 0.14678   -17.66088 14.61047 1.000 12.39098 ? 260 VAL A HB   1 
ATOM   3750 H  HG11 . VAL A 1 237 ? 0.48180   -15.35722 15.10396 1.000 13.12364 ? 260 VAL A HG11 1 
ATOM   3751 H  HG12 . VAL A 1 237 ? 0.80310   -15.81420 13.61687 1.000 13.12364 ? 260 VAL A HG12 1 
ATOM   3752 H  HG13 . VAL A 1 237 ? -0.55567  -15.05694 13.93906 1.000 13.12364 ? 260 VAL A HG13 1 
ATOM   3753 H  HG21 . VAL A 1 237 ? -0.76686  -16.88483 16.59644 1.000 13.06539 ? 260 VAL A HG21 1 
ATOM   3754 H  HG22 . VAL A 1 237 ? -2.08524  -16.43292 15.83410 1.000 13.06539 ? 260 VAL A HG22 1 
ATOM   3755 H  HG23 . VAL A 1 237 ? -1.73596  -17.97662 15.97007 1.000 13.06539 ? 260 VAL A HG23 1 
ATOM   3756 N  N    . THR A 1 238 ? -1.23190  -16.26698 11.25686 1.000 8.54417  ? 261 THR A N    1 
ATOM   3757 C  CA   . THR A 1 238 ? -0.54239  -15.91334 10.02512 1.000 9.28712  ? 261 THR A CA   1 
ATOM   3758 C  C    . THR A 1 238 ? -0.23551  -14.42867 10.06609 1.000 8.98162  ? 261 THR A C    1 
ATOM   3759 O  O    . THR A 1 238 ? -1.15696  -13.61255 10.05500 1.000 9.17817  ? 261 THR A O    1 
ATOM   3760 C  CB   . THR A 1 238 ? -1.37746  -16.22621 8.78759  1.000 9.31380  ? 261 THR A CB   1 
ATOM   3761 O  OG1  . THR A 1 238 ? -2.64838  -15.57334 8.86633  1.000 9.80976  ? 261 THR A OG1  1 
ATOM   3762 C  CG2  . THR A 1 238 ? -1.64490  -17.70062 8.65554  1.000 10.82167 ? 261 THR A CG2  1 
ATOM   3763 H  H    . THR A 1 238 ? -1.91846  -15.77530 11.41960 1.000 10.25300 ? 261 THR A H    1 
ATOM   3764 H  HA   . THR A 1 238 ? 0.28211   -16.42213 9.97793  1.000 11.14454 ? 261 THR A HA   1 
ATOM   3765 H  HB   . THR A 1 238 ? -0.87864  -15.91875 8.01457  1.000 11.17656 ? 261 THR A HB   1 
ATOM   3766 H  HG1  . THR A 1 238 ? -2.54203  -14.75640 9.03033  1.000 11.77172 ? 261 THR A HG1  1 
ATOM   3767 H  HG21 . THR A 1 238 ? -2.24379  -17.86371 7.91013  1.000 12.98601 ? 261 THR A HG21 1 
ATOM   3768 H  HG22 . THR A 1 238 ? -0.81360  -18.17607 8.50131  1.000 12.98601 ? 261 THR A HG22 1 
ATOM   3769 H  HG23 . THR A 1 238 ? -2.05425  -18.03759 9.46781  1.000 12.98601 ? 261 THR A HG23 1 
ATOM   3770 N  N    A TYR A 1 239 ? 1.04783   -14.09669 10.08343 0.763 9.11916  ? 262 TYR A N    1 
ATOM   3771 N  N    B TYR A 1 239 ? 1.04418   -14.08750 10.17512 0.237 8.62155  ? 262 TYR A N    1 
ATOM   3772 C  CA   A TYR A 1 239 ? 1.52833   -12.72813 10.12845 0.763 9.71008  ? 262 TYR A CA   1 
ATOM   3773 C  CA   B TYR A 1 239 ? 1.49940   -12.70963 10.11521 0.237 8.62766  ? 262 TYR A CA   1 
ATOM   3774 C  C    A TYR A 1 239 ? 2.31775   -12.45481 8.85541  0.763 9.64743  ? 262 TYR A C    1 
ATOM   3775 C  C    B TYR A 1 239 ? 2.21311   -12.48923 8.78878  0.237 8.32845  ? 262 TYR A C    1 
ATOM   3776 O  O    A TYR A 1 239 ? 3.08217   -13.30670 8.40127  0.763 10.14379 ? 262 TYR A O    1 
ATOM   3777 O  O    B TYR A 1 239 ? 2.82560   -13.40676 8.23557  0.237 8.39673  ? 262 TYR A O    1 
ATOM   3778 C  CB   A TYR A 1 239 ? 2.41020   -12.57663 11.37845 0.763 9.61771  ? 262 TYR A CB   1 
ATOM   3779 C  CB   B TYR A 1 239 ? 2.47479   -12.38968 11.25408 0.237 8.42549  ? 262 TYR A CB   1 
ATOM   3780 C  CG   A TYR A 1 239 ? 1.69108   -12.36151 12.71360 0.763 10.04899 ? 262 TYR A CG   1 
ATOM   3781 C  CG   B TYR A 1 239 ? 1.89559   -12.48037 12.65266 0.237 9.33816  ? 262 TYR A CG   1 
ATOM   3782 C  CD1  A TYR A 1 239 ? 0.32887   -12.09771 12.77796 0.763 10.74601 ? 262 TYR A CD1  1 
ATOM   3783 C  CD1  B TYR A 1 239 ? 0.54837   -12.23423 12.89624 0.237 10.12857 ? 262 TYR A CD1  1 
ATOM   3784 C  CD2  A TYR A 1 239 ? 2.40075   -12.34814 13.91105 0.763 9.35223  ? 262 TYR A CD2  1 
ATOM   3785 C  CD2  B TYR A 1 239 ? 2.70762   -12.79419 13.73585 0.237 10.85735 ? 262 TYR A CD2  1 
ATOM   3786 C  CE1  A TYR A 1 239 ? -0.30265  -11.82989 13.99068 0.763 9.81964  ? 262 TYR A CE1  1 
ATOM   3787 C  CE1  B TYR A 1 239 ? 0.02854   -12.30111 14.18044 0.237 10.70177 ? 262 TYR A CE1  1 
ATOM   3788 C  CE2  A TYR A 1 239 ? 1.77610   -12.08967 15.11120 0.763 9.88622  ? 262 TYR A CE2  1 
ATOM   3789 C  CE2  B TYR A 1 239 ? 2.19855   -12.86447 15.01455 0.237 11.99015 ? 262 TYR A CE2  1 
ATOM   3790 C  CZ   A TYR A 1 239 ? 0.43304   -11.84854 15.14794 0.763 8.57297  ? 262 TYR A CZ   1 
ATOM   3791 C  CZ   B TYR A 1 239 ? 0.86223   -12.61779 15.22785 0.237 11.74422 ? 262 TYR A CZ   1 
ATOM   3792 O  OH   A TYR A 1 239 ? -0.14994  -11.55926 16.36379 0.763 9.13506  ? 262 TYR A OH   1 
ATOM   3793 O  OH   B TYR A 1 239 ? 0.37272   -12.70151 16.50654 0.237 12.64053 ? 262 TYR A OH   1 
ATOM   3794 H  H    A TYR A 1 239 ? 1.68532   -14.67375 10.06907 0.763 10.94299 ? 262 TYR A H    1 
ATOM   3795 H  H    B TYR A 1 239 ? 1.68157   -14.65386 10.28726 0.237 10.34586 ? 262 TYR A H    1 
ATOM   3796 H  HA   A TYR A 1 239 ? 0.81105   -12.07622 10.16627 0.763 11.65210 ? 262 TYR A HA   1 
ATOM   3797 H  HA   B TYR A 1 239 ? 0.73948   -12.11143 10.18991 0.237 10.35319 ? 262 TYR A HA   1 
ATOM   3798 H  HB2  A TYR A 1 239 ? 2.94055   -13.38360 11.47026 0.763 11.54125 ? 262 TYR A HB2  1 
ATOM   3799 H  HB2  B TYR A 1 239 ? 3.21493   -13.01487 11.20684 0.237 10.11059 ? 262 TYR A HB2  1 
ATOM   3800 H  HB3  A TYR A 1 239 ? 2.99099   -11.81142 11.24413 0.763 11.54125 ? 262 TYR A HB3  1 
ATOM   3801 H  HB3  B TYR A 1 239 ? 2.79808   -11.48312 11.13353 0.237 10.11059 ? 262 TYR A HB3  1 
ATOM   3802 H  HD1  A TYR A 1 239 ? -0.17247  -12.09989 11.99467 0.763 12.89521 ? 262 TYR A HD1  1 
ATOM   3803 H  HD1  B TYR A 1 239 ? -0.01319  -12.02127 12.18617 0.237 12.15428 ? 262 TYR A HD1  1 
ATOM   3804 H  HD2  A TYR A 1 239 ? 3.31521   -12.51714 13.90055 0.763 11.22268 ? 262 TYR A HD2  1 
ATOM   3805 H  HD2  B TYR A 1 239 ? 3.61185   -12.95994 13.59514 0.237 13.02882 ? 262 TYR A HD2  1 
ATOM   3806 H  HE1  A TYR A 1 239 ? -1.21286  -11.64060 14.01513 0.763 11.78356 ? 262 TYR A HE1  1 
ATOM   3807 H  HE1  B TYR A 1 239 ? -0.87367  -12.13371 14.33172 0.237 12.84213 ? 262 TYR A HE1  1 
ATOM   3808 H  HE2  A TYR A 1 239 ? 2.27077   -12.07942 15.89866 0.763 11.86346 ? 262 TYR A HE2  1 
ATOM   3809 H  HE2  B TYR A 1 239 ? 2.75494   -13.07732 15.72871 0.237 14.38818 ? 262 TYR A HE2  1 
ATOM   3810 H  HH   A TYR A 1 239 ? -0.80622  -11.04678 16.25304 0.763 10.96208 ? 262 TYR A HH   1 
ATOM   3811 H  HH   B TYR A 1 239 ? 1.00633   -12.69180 17.05794 0.237 15.16864 ? 262 TYR A HH   1 
ATOM   3812 N  N    . PHE A 1 240 ? 2.15477   -11.26139 8.29006  1.000 9.55286  ? 263 PHE A N    1 
ATOM   3813 C  CA   . PHE A 1 240 ? 2.82926   -10.94845 7.03645  1.000 9.80948  ? 263 PHE A CA   1 
ATOM   3814 C  C    . PHE A 1 240 ? 3.15872   -9.47057  7.00100  1.000 10.04233 ? 263 PHE A C    1 
ATOM   3815 O  O    . PHE A 1 240 ? 2.32554   -8.63873  7.33423  1.000 10.25231 ? 263 PHE A O    1 
ATOM   3816 C  CB   . PHE A 1 240 ? 1.93769   -11.34714 5.84748  1.000 10.29492 ? 263 PHE A CB   1 
ATOM   3817 C  CG   . PHE A 1 240 ? 2.55555   -11.06859 4.50462  1.000 10.48058 ? 263 PHE A CG   1 
ATOM   3818 C  CD1  . PHE A 1 240 ? 3.64660   -11.79334 4.08963  1.000 10.13115 ? 263 PHE A CD1  1 
ATOM   3819 C  CD2  . PHE A 1 240 ? 2.05641   -10.10048 3.67460  1.000 10.53131 ? 263 PHE A CD2  1 
ATOM   3820 C  CE1  . PHE A 1 240 ? 4.24495   -11.54376 2.88424  1.000 10.91918 ? 263 PHE A CE1  1 
ATOM   3821 C  CE2  . PHE A 1 240 ? 2.64205   -9.85485  2.45197  1.000 10.96189 ? 263 PHE A CE2  1 
ATOM   3822 C  CZ   . PHE A 1 240 ? 3.74416   -10.57205 2.06505  1.000 11.80713 ? 263 PHE A CZ   1 
ATOM   3823 H  H    A PHE A 1 240 ? 1.66728   -10.62840 8.60828  0.763 11.46343 ? 263 PHE A H    1 
ATOM   3824 H  H    B PHE A 1 240 ? 1.73784   -10.60231 8.65251  0.237 11.46343 ? 263 PHE A H    1 
ATOM   3825 H  HA   . PHE A 1 240 ? 3.67028   -11.42725 6.97048  1.000 11.77138 ? 263 PHE A HA   1 
ATOM   3826 H  HB2  . PHE A 1 240 ? 1.75746   -12.29888 5.89846  1.000 12.35391 ? 263 PHE A HB2  1 
ATOM   3827 H  HB3  . PHE A 1 240 ? 1.10707   -10.84892 5.89997  1.000 12.35391 ? 263 PHE A HB3  1 
ATOM   3828 H  HD1  . PHE A 1 240 ? 3.98429   -12.46497 4.63716  1.000 12.15739 ? 263 PHE A HD1  1 
ATOM   3829 H  HD2  . PHE A 1 240 ? 1.31543   -9.60435  3.93861  1.000 12.63757 ? 263 PHE A HD2  1 
ATOM   3830 H  HE1  . PHE A 1 240 ? 4.99066   -12.03453 2.62353  1.000 13.10302 ? 263 PHE A HE1  1 
ATOM   3831 H  HE2  . PHE A 1 240 ? 2.28993   -9.20306  1.88975  1.000 13.15427 ? 263 PHE A HE2  1 
ATOM   3832 H  HZ   . PHE A 1 240 ? 4.15008   -10.39753 1.24671  1.000 14.16856 ? 263 PHE A HZ   1 
ATOM   3833 N  N    . THR A 1 241 ? 4.37980   -9.13409  6.57302  1.000 9.98704  ? 264 THR A N    1 
ATOM   3834 C  CA   . THR A 1 241 ? 4.77441   -7.73728  6.44294  1.000 10.16361 ? 264 THR A CA   1 
ATOM   3835 C  C    . THR A 1 241 ? 5.70485   -7.59688  5.24542  1.000 9.93664  ? 264 THR A C    1 
ATOM   3836 O  O    . THR A 1 241 ? 6.27649   -8.58077  4.77259  1.000 12.16623 ? 264 THR A O    1 
ATOM   3837 C  CB   . THR A 1 241 ? 5.36168   -7.23833  7.75947  1.000 10.71469 ? 264 THR A CB   1 
ATOM   3838 O  OG1  . THR A 1 241 ? 5.46567   -5.82276  7.72851  1.000 11.18142 ? 264 THR A OG1  1 
ATOM   3839 C  CG2  . THR A 1 241 ? 6.70740   -7.85790  8.04304  1.000 11.55495 ? 264 THR A CG2  1 
ATOM   3840 H  H    . THR A 1 241 ? 4.99129   -9.69776  6.35403  1.000 11.98445 ? 264 THR A H    1 
ATOM   3841 H  HA   . THR A 1 241 ? 4.02225   -7.15899  6.24111  1.000 12.19633 ? 264 THR A HA   1 
ATOM   3842 H  HB   . THR A 1 241 ? 4.77452   -7.49936  8.48611  1.000 12.85763 ? 264 THR A HB   1 
ATOM   3843 H  HG1  . THR A 1 241 ? 4.71888   -5.48373  7.54697  1.000 13.41770 ? 264 THR A HG1  1 
ATOM   3844 H  HG21 . THR A 1 241 ? 6.97544   -7.66588  8.95528  1.000 13.86594 ? 264 THR A HG21 1 
ATOM   3845 H  HG22 . THR A 1 241 ? 6.66159   -8.81950  7.92418  1.000 13.86594 ? 264 THR A HG22 1 
ATOM   3846 H  HG23 . THR A 1 241 ? 7.37311   -7.49712  7.43677  1.000 13.86594 ? 264 THR A HG23 1 
ATOM   3847 N  N    . GLN A 1 242 ? 5.82809   -6.37952  4.73394  1.000 11.02802 ? 265 GLN A N    1 
ATOM   3848 C  CA   . GLN A 1 242 ? 6.42261   -6.12321  3.43367  1.000 11.13310 ? 265 GLN A CA   1 
ATOM   3849 C  C    . GLN A 1 242 ? 7.49156   -5.05077  3.54210  1.000 12.58190 ? 265 GLN A C    1 
ATOM   3850 O  O    . GLN A 1 242 ? 7.53368   -4.29267  4.51554  1.000 12.92516 ? 265 GLN A O    1 
ATOM   3851 C  CB   . GLN A 1 242 ? 5.34170   -5.70166  2.42912  1.000 11.21309 ? 265 GLN A CB   1 
ATOM   3852 C  CG   . GLN A 1 242 ? 4.33931   -6.80946  2.25687  1.000 12.74251 ? 265 GLN A CG   1 
ATOM   3853 C  CD   . GLN A 1 242 ? 3.24688   -6.45417  1.29399  1.000 12.45279 ? 265 GLN A CD   1 
ATOM   3854 O  OE1  . GLN A 1 242 ? 3.47349   -6.37998  0.09325  1.000 14.66891 ? 265 GLN A OE1  1 
ATOM   3855 N  NE2  . GLN A 1 242 ? 2.05185   -6.22272  1.80737  1.000 11.80403 ? 265 GLN A NE2  1 
ATOM   3856 H  H    . GLN A 1 242 ? 5.56569   -5.66604  5.13604  1.000 13.23363 ? 265 GLN A H    1 
ATOM   3857 H  HA   . GLN A 1 242 ? 6.85760   -6.92668  3.10789  1.000 13.35972 ? 265 GLN A HA   1 
ATOM   3858 H  HB2  . GLN A 1 242 ? 4.88175   -4.91295  2.75667  1.000 13.45571 ? 265 GLN A HB2  1 
ATOM   3859 H  HB3  . GLN A 1 242 ? 5.75041   -5.51437  1.56960  1.000 13.45571 ? 265 GLN A HB3  1 
ATOM   3860 H  HG2  . GLN A 1 242 ? 4.79315   -7.59736  1.91901  1.000 15.29101 ? 265 GLN A HG2  1 
ATOM   3861 H  HG3  . GLN A 1 242 ? 3.93171   -7.00392  3.11532  1.000 15.29101 ? 265 GLN A HG3  1 
ATOM   3862 H  HE21 . GLN A 1 242 ? 1.93050   -6.27923  2.65689  1.000 14.16484 ? 265 GLN A HE21 1 
ATOM   3863 H  HE22 . GLN A 1 242 ? 1.39525   -6.01554  1.29205  1.000 14.16484 ? 265 GLN A HE22 1 
ATOM   3864 N  N    . PRO A 1 243 ? 8.34948   -4.92729  2.52607  1.000 13.47362 ? 266 PRO A N    1 
ATOM   3865 C  CA   . PRO A 1 243 ? 9.48487   -4.00841  2.66588  1.000 14.83742 ? 266 PRO A CA   1 
ATOM   3866 C  C    . PRO A 1 243 ? 9.14719   -2.55366  2.41219  1.000 14.14115 ? 266 PRO A C    1 
ATOM   3867 O  O    . PRO A 1 243 ? 9.91385   -1.67335  2.84347  1.000 16.41206 ? 266 PRO A O    1 
ATOM   3868 C  CB   . PRO A 1 243 ? 10.51444  -4.52795  1.65328  1.000 17.74077 ? 266 PRO A CB   1 
ATOM   3869 C  CG   . PRO A 1 243 ? 9.85232   -5.52573  0.82131  1.000 17.99037 ? 266 PRO A CG   1 
ATOM   3870 C  CD   . PRO A 1 243 ? 8.51104   -5.87939  1.41004  1.000 15.29520 ? 266 PRO A CD   1 
ATOM   3871 H  HA   . PRO A 1 243 ? 9.85964   -4.09433  3.55642  1.000 17.80491 ? 266 PRO A HA   1 
ATOM   3872 H  HB2  . PRO A 1 243 ? 10.82769  -3.78883  1.10879  1.000 21.28893 ? 266 PRO A HB2  1 
ATOM   3873 H  HB3  . PRO A 1 243 ? 11.25854  -4.92693  2.13081  1.000 21.28893 ? 266 PRO A HB3  1 
ATOM   3874 H  HG2  . PRO A 1 243 ? 9.73354   -5.15809  -0.06842 1.000 21.58844 ? 266 PRO A HG2  1 
ATOM   3875 H  HG3  . PRO A 1 243 ? 10.41208  -6.31692  0.78135  1.000 21.58844 ? 266 PRO A HG3  1 
ATOM   3876 H  HD2  . PRO A 1 243 ? 7.80672   -5.76070  0.75372  1.000 18.35424 ? 266 PRO A HD2  1 
ATOM   3877 H  HD3  . PRO A 1 243 ? 8.51011   -6.79293  1.73615  1.000 18.35424 ? 266 PRO A HD3  1 
ATOM   3878 N  N    . GLN A 1 244 ? 8.03400   -2.26996  1.72294  1.000 14.34252 ? 267 GLN A N    1 
ATOM   3879 C  CA   . GLN A 1 244 ? 7.71610   -0.90609  1.30329  1.000 14.04449 ? 267 GLN A CA   1 
ATOM   3880 C  C    . GLN A 1 244 ? 6.76659   -0.24965  2.28958  1.000 13.97784 ? 267 GLN A C    1 
ATOM   3881 O  O    . GLN A 1 244 ? 5.74002   -0.84894  2.63833  1.000 13.57011 ? 267 GLN A O    1 
ATOM   3882 C  CB   . GLN A 1 244 ? 7.04597   -0.93209  -0.06755 1.000 14.07668 ? 267 GLN A CB   1 
ATOM   3883 C  CG   . GLN A 1 244 ? 7.88986   -1.56810  -1.16929 1.000 15.58899 ? 267 GLN A CG   1 
ATOM   3884 C  CD   . GLN A 1 244 ? 7.61933   -3.03374  -1.31654 1.000 15.29580 ? 267 GLN A CD   1 
ATOM   3885 O  OE1  . GLN A 1 244 ? 6.80956   -3.62033  -0.58341 1.000 14.85510 ? 267 GLN A OE1  1 
ATOM   3886 N  NE2  . GLN A 1 244 ? 8.29212   -3.64668  -2.26950 1.000 16.21093 ? 267 GLN A NE2  1 
ATOM   3887 H  H    . GLN A 1 244 ? 7.44790   -2.85356  1.48736  1.000 17.21102 ? 267 GLN A H    1 
ATOM   3888 H  HA   . GLN A 1 244 ? 8.53437   -0.38668  1.26371  1.000 16.85338 ? 267 GLN A HA   1 
ATOM   3889 H  HB2  . GLN A 1 244 ? 6.22179   -1.43904  0.00052  1.000 16.89201 ? 267 GLN A HB2  1 
ATOM   3890 H  HB3  . GLN A 1 244 ? 6.85322   -0.01986  -0.33508 1.000 16.89201 ? 267 GLN A HB3  1 
ATOM   3891 H  HG2  . GLN A 1 244 ? 7.68684   -1.13710  -2.01423 1.000 18.70679 ? 267 GLN A HG2  1 
ATOM   3892 H  HG3  . GLN A 1 244 ? 8.82927   -1.45428  -0.95608 1.000 18.70679 ? 267 GLN A HG3  1 
ATOM   3893 H  HE21 . GLN A 1 244 ? 8.84422   -3.20455  -2.75870 1.000 19.45312 ? 267 GLN A HE21 1 
ATOM   3894 H  HE22 . GLN A 1 244 ? 8.17911   -4.48883  -2.40223 1.000 19.45312 ? 267 GLN A HE22 1 
ATOM   3895 N  N    . PRO A 1 245 ? 7.03635   0.96971   2.73463  1.000 14.66024 ? 268 PRO A N    1 
ATOM   3896 C  CA   . PRO A 1 245 ? 6.14124   1.58993   3.72076  1.000 14.69248 ? 268 PRO A CA   1 
ATOM   3897 C  C    . PRO A 1 245 ? 4.68981   1.63294   3.27915  1.000 14.27471 ? 268 PRO A C    1 
ATOM   3898 O  O    . PRO A 1 245 ? 3.78273   1.47464   4.10960  1.000 15.59975 ? 268 PRO A O    1 
ATOM   3899 C  CB   . PRO A 1 245 ? 6.71696   3.00116   3.89103  1.000 16.56328 ? 268 PRO A CB   1 
ATOM   3900 C  CG   . PRO A 1 245 ? 8.08704   2.93947   3.38437  1.000 17.87769 ? 268 PRO A CG   1 
ATOM   3901 C  CD   . PRO A 1 245 ? 8.22223   1.79746   2.45384  1.000 15.97633 ? 268 PRO A CD   1 
ATOM   3902 H  HA   . PRO A 1 245 ? 6.21222   1.11129   4.56145  1.000 17.63097 ? 268 PRO A HA   1 
ATOM   3903 H  HB2  . PRO A 1 245 ? 6.18900   3.63305   3.37831  1.000 19.87593 ? 268 PRO A HB2  1 
ATOM   3904 H  HB3  . PRO A 1 245 ? 6.70825   3.24612   4.82955  1.000 19.87593 ? 268 PRO A HB3  1 
ATOM   3905 H  HG2  . PRO A 1 245 ? 8.28509   3.76788   2.92023  1.000 21.45323 ? 268 PRO A HG2  1 
ATOM   3906 H  HG3  . PRO A 1 245 ? 8.69171   2.82668   4.13441  1.000 21.45323 ? 268 PRO A HG3  1 
ATOM   3907 H  HD2  . PRO A 1 245 ? 8.21706   2.10284   1.53318  1.000 19.17159 ? 268 PRO A HD2  1 
ATOM   3908 H  HD3  . PRO A 1 245 ? 9.03657   1.30240   2.63460  1.000 19.17159 ? 268 PRO A HD3  1 
ATOM   3909 N  N    . LYS A 1 246 ? 4.44692   1.87014   1.98794  1.000 14.45844 ? 269 LYS A N    1 
ATOM   3910 C  CA   . LYS A 1 246 ? 3.09727   2.03007   1.47117  1.000 14.55345 ? 269 LYS A CA   1 
ATOM   3911 C  C    . LYS A 1 246 ? 2.60052   0.79389   0.73473  1.000 13.68277 ? 269 LYS A C    1 
ATOM   3912 O  O    . LYS A 1 246 ? 1.68869   0.88827   -0.09529 1.000 15.98032 ? 269 LYS A O    1 
ATOM   3913 C  CB   . LYS A 1 246 ? 3.01338   3.25224   0.55826  1.000 16.47320 ? 269 LYS A CB   1 
ATOM   3914 C  CG   . LYS A 1 246 ? 3.36038   4.55746   1.23246  1.000 20.35260 ? 269 LYS A CG   1 
ATOM   3915 C  CD   . LYS A 1 246 ? 3.22940   5.71410   0.23857  1.000 24.73010 ? 269 LYS A CD   1 
ATOM   3916 C  CE   . LYS A 1 246 ? 3.58415   7.04359   0.88734  1.000 30.09798 ? 269 LYS A CE   1 
ATOM   3917 N  NZ   . LYS A 1 246 ? 3.47720   8.17682   -0.06232 1.000 33.94023 ? 269 LYS A NZ   1 
ATOM   3918 H  H    . LYS A 1 246 ? 5.05941   1.94261   1.38860  1.000 17.35013 ? 269 LYS A H    1 
ATOM   3919 H  HA   . LYS A 1 246 ? 2.50691   2.18153   2.22579  1.000 17.46414 ? 269 LYS A HA   1 
ATOM   3920 H  HB2  . LYS A 1 246 ? 3.63046   3.12999   -0.18009 1.000 19.76784 ? 269 LYS A HB2  1 
ATOM   3921 H  HB3  . LYS A 1 246 ? 2.10605   3.32680   0.22347  1.000 19.76784 ? 269 LYS A HB3  1 
ATOM   3922 H  HG2  . LYS A 1 246 ? 2.75374   4.71394   1.97300  1.000 24.42312 ? 269 LYS A HG2  1 
ATOM   3923 H  HG3  . LYS A 1 246 ? 4.27505   4.52601   1.55383  1.000 24.42312 ? 269 LYS A HG3  1 
ATOM   3924 H  HD2  . LYS A 1 246 ? 3.83202   5.56755   -0.50728 1.000 29.67613 ? 269 LYS A HD2  1 
ATOM   3925 H  HD3  . LYS A 1 246 ? 2.31424   5.76361   -0.07911 1.000 29.67613 ? 269 LYS A HD3  1 
ATOM   3926 H  HE2  . LYS A 1 246 ? 2.97708   7.20974   1.62542  1.000 36.11757 ? 269 LYS A HE2  1 
ATOM   3927 H  HE3  . LYS A 1 246 ? 4.49773   7.00612   1.21118  1.000 36.11757 ? 269 LYS A HE3  1 
ATOM   3928 H  HZ1  . LYS A 1 246 ? 3.80417   8.91678   0.30869  1.000 40.72827 ? 269 LYS A HZ1  1 
ATOM   3929 H  HZ2  . LYS A 1 246 ? 3.93692   7.99767   -0.80304 1.000 40.72827 ? 269 LYS A HZ2  1 
ATOM   3930 H  HZ3  . LYS A 1 246 ? 2.62462   8.31411   -0.27764 1.000 40.72827 ? 269 LYS A HZ3  1 
ATOM   3931 N  N    . ALA A 1 247 ? 3.19056   -0.36262  0.99935  1.000 13.25142 ? 270 ALA A N    1 
ATOM   3932 C  CA   . ALA A 1 247 ? 2.70058   -1.57953  0.37972  1.000 13.77905 ? 270 ALA A CA   1 
ATOM   3933 C  C    . ALA A 1 247 ? 1.22507   -1.79323  0.70967  1.000 13.78761 ? 270 ALA A C    1 
ATOM   3934 O  O    . ALA A 1 247 ? 0.73679   -1.43921  1.79099  1.000 14.42000 ? 270 ALA A O    1 
ATOM   3935 C  CB   . ALA A 1 247 ? 3.50390   -2.76469  0.88817  1.000 13.13813 ? 270 ALA A CB   1 
ATOM   3936 H  H    . ALA A 1 247 ? 3.86367   -0.46656  1.52444  1.000 15.90170 ? 270 ALA A H    1 
ATOM   3937 H  HA   . ALA A 1 247 ? 2.79480   -1.51673  -0.58365 1.000 16.53486 ? 270 ALA A HA   1 
ATOM   3938 H  HB1  . ALA A 1 247 ? 3.14308   -3.57897  0.50391  1.000 15.76575 ? 270 ALA A HB1  1 
ATOM   3939 H  HB2  . ALA A 1 247 ? 4.43034   -2.65568  0.62223  1.000 15.76575 ? 270 ALA A HB2  1 
ATOM   3940 H  HB3  . ALA A 1 247 ? 3.43920   -2.79844  1.85542  1.000 15.76575 ? 270 ALA A HB3  1 
ATOM   3941 N  N    A GLU A 1 248 ? 0.50488   -2.38027  -0.23918 0.416 14.22953 ? 271 GLU A N    1 
ATOM   3942 N  N    B GLU A 1 248 ? 0.51321   -2.39115  -0.24693 0.584 13.89878 ? 271 GLU A N    1 
ATOM   3943 C  CA   A GLU A 1 248 ? -0.90322  -2.66186  -0.01748 0.416 15.46278 ? 271 GLU A CA   1 
ATOM   3944 C  CA   B GLU A 1 248 ? -0.89256  -2.71682  -0.07040 0.584 15.46136 ? 271 GLU A CA   1 
ATOM   3945 C  C    A GLU A 1 248 ? -1.08134  -3.97146  0.74305  0.416 13.86661 ? 271 GLU A C    1 
ATOM   3946 C  C    B GLU A 1 248 ? -1.05392  -3.96015  0.79940  0.584 13.76014 ? 271 GLU A C    1 
ATOM   3947 O  O    A GLU A 1 248 ? -0.21589  -4.84741  0.74630  0.416 13.69985 ? 271 GLU A O    1 
ATOM   3948 O  O    B GLU A 1 248 ? -0.14773  -4.78289  0.93708  0.584 14.32444 ? 271 GLU A O    1 
ATOM   3949 C  CB   A GLU A 1 248 ? -1.64852  -2.72991  -1.34995 0.416 19.17133 ? 271 GLU A CB   1 
ATOM   3950 C  CB   B GLU A 1 248 ? -1.56056  -2.96622  -1.42971 0.584 19.73946 ? 271 GLU A CB   1 
ATOM   3951 C  CG   A GLU A 1 248 ? -1.72901  -1.39669  -2.07711 0.416 22.59399 ? 271 GLU A CG   1 
ATOM   3952 C  CG   B GLU A 1 248 ? -1.21824  -4.30863  -2.06709 0.584 24.09756 ? 271 GLU A CG   1 
ATOM   3953 C  CD   A GLU A 1 248 ? -2.53886  -1.47436  -3.35719 0.416 26.25358 ? 271 GLU A CD   1 
ATOM   3954 C  CD   B GLU A 1 248 ? -1.96323  -4.56989  -3.36730 0.584 28.08235 ? 271 GLU A CD   1 
ATOM   3955 O  OE1  A GLU A 1 248 ? -2.86457  -2.60327  -3.78658 0.416 27.28158 ? 271 GLU A OE1  1 
ATOM   3956 O  OE1  B GLU A 1 248 ? -3.02512  -3.94634  -3.59012 0.584 30.06004 ? 271 GLU A OE1  1 
ATOM   3957 O  OE2  A GLU A 1 248 ? -2.85051  -0.41083  -3.93315 0.416 28.43593 ? 271 GLU A OE2  1 
ATOM   3958 O  OE2  B GLU A 1 248 ? -1.47711  -5.39685  -4.17137 0.584 28.64100 ? 271 GLU A OE2  1 
ATOM   3959 H  H    A GLU A 1 248 ? 0.80557   -2.62107  -1.00807 0.416 17.07543 ? 271 GLU A H    1 
ATOM   3960 H  H    B GLU A 1 248 ? 0.82863   -2.61916  -1.01382 0.584 16.67854 ? 271 GLU A H    1 
ATOM   3961 H  HA   A GLU A 1 248 ? -1.29104  -1.94980  0.51494  0.416 18.55533 ? 271 GLU A HA   1 
ATOM   3962 H  HA   B GLU A 1 248 ? -1.33585  -1.97224  0.36549  0.584 18.55363 ? 271 GLU A HA   1 
ATOM   3963 H  HB2  A GLU A 1 248 ? -1.19067  -3.35695  -1.93141 0.416 23.00560 ? 271 GLU A HB2  1 
ATOM   3964 H  HB2  B GLU A 1 248 ? -2.52279  -2.93533  -1.31113 0.584 23.68735 ? 271 GLU A HB2  1 
ATOM   3965 H  HB3  A GLU A 1 248 ? -2.55532  -3.03207  -1.18470 0.416 23.00560 ? 271 GLU A HB3  1 
ATOM   3966 H  HB3  B GLU A 1 248 ? -1.27949  -2.27025  -2.04414 0.584 23.68735 ? 271 GLU A HB3  1 
ATOM   3967 H  HG2  A GLU A 1 248 ? -2.14944  -0.74423  -1.49535 0.416 27.11279 ? 271 GLU A HG2  1 
ATOM   3968 H  HG2  B GLU A 1 248 ? -0.26786  -4.33061  -2.25995 0.584 28.91707 ? 271 GLU A HG2  1 
ATOM   3969 H  HG3  A GLU A 1 248 ? -0.83213  -1.10724  -2.30672 0.416 27.11279 ? 271 GLU A HG3  1 
ATOM   3970 H  HG3  B GLU A 1 248 ? -1.44723  -5.01776  -1.44612 0.584 28.91707 ? 271 GLU A HG3  1 
ATOM   3971 N  N    . SER A 1 249 ? -2.24468  -4.10539  1.36863  1.000 14.21989 ? 272 SER A N    1 
ATOM   3972 C  CA   . SER A 1 249 ? -2.55461  -5.30510  2.12032  1.000 15.16482 ? 272 SER A CA   1 
ATOM   3973 C  C    . SER A 1 249 ? -2.53262  -6.52891  1.21927  1.000 13.90601 ? 272 SER A C    1 
ATOM   3974 O  O    . SER A 1 249 ? -2.83863  -6.44948  0.02665  1.000 15.35196 ? 272 SER A O    1 
ATOM   3975 C  CB   . SER A 1 249 ? -3.95767  -5.19210  2.71230  1.000 19.04759 ? 272 SER A CB   1 
ATOM   3976 O  OG   . SER A 1 249 ? -4.00207  -4.20308  3.71277  1.000 22.91796 ? 272 SER A OG   1 
ATOM   3977 H  H    . SER A 1 249 ? -2.88004  -3.52698  1.33166  1.000 17.06386 ? 272 SER A H    1 
ATOM   3978 H  HA   . SER A 1 249 ? -1.89761  -5.41107  2.82603  1.000 18.19778 ? 272 SER A HA   1 
ATOM   3979 H  HB2  . SER A 1 249 ? -4.57977  -4.95538  2.00671  1.000 22.85710 ? 272 SER A HB2  1 
ATOM   3980 H  HB3  . SER A 1 249 ? -4.20589  -6.04548  3.10093  1.000 22.85710 ? 272 SER A HB3  1 
ATOM   3981 H  HG   . SER A 1 249 ? -3.94409  -3.44040  3.36556  1.000 27.50155 ? 272 SER A HG   1 
ATOM   3982 N  N    . ARG A 1 250 ? -2.21208  -7.68233  1.81220  1.000 12.79222 ? 273 ARG A N    1 
ATOM   3983 C  CA   . ARG A 1 250 ? -2.14425  -8.94780  1.07684  1.000 13.34089 ? 273 ARG A CA   1 
ATOM   3984 C  C    . ARG A 1 250 ? -2.87112  -10.03860 1.86550  1.000 11.50977 ? 273 ARG A C    1 
ATOM   3985 O  O    . ARG A 1 250 ? -2.29002  -11.01283 2.33563  1.000 11.93352 ? 273 ARG A O    1 
ATOM   3986 C  CB   . ARG A 1 250 ? -0.69191  -9.33107  0.80506  1.000 13.43790 ? 273 ARG A CB   1 
ATOM   3987 C  CG   . ARG A 1 250 ? -0.00995  -8.40192  -0.19656 1.000 14.38864 ? 273 ARG A CG   1 
ATOM   3988 C  CD   . ARG A 1 250 ? -0.62123  -8.47425  -1.60737 1.000 16.28912 ? 273 ARG A CD   1 
ATOM   3989 N  NE   . ARG A 1 250 ? -0.68837  -9.82791  -2.13596 1.000 18.08127 ? 273 ARG A NE   1 
ATOM   3990 C  CZ   . ARG A 1 250 ? 0.30082   -10.42261 -2.78831 1.000 19.71786 ? 273 ARG A CZ   1 
ATOM   3991 N  NH1  . ARG A 1 250 ? 1.45928   -9.81802  -2.97732 1.000 20.43990 ? 273 ARG A NH1  1 
ATOM   3992 N  NH2  . ARG A 1 250 ? 0.12320   -11.65394 -3.25524 1.000 21.77914 ? 273 ARG A NH2  1 
ATOM   3993 H  H    . ARG A 1 250 ? -2.02778  -7.75725  2.64887  1.000 15.35066 ? 273 ARG A H    1 
ATOM   3994 H  HA   . ARG A 1 250 ? -2.60380  -8.84787  0.22848  1.000 16.00907 ? 273 ARG A HA   1 
ATOM   3995 H  HB2  . ARG A 1 250 ? -0.19467  -9.29194  1.63700  1.000 16.12548 ? 273 ARG A HB2  1 
ATOM   3996 H  HB3  . ARG A 1 250 ? -0.66566  -10.23134 0.44490  1.000 16.12548 ? 273 ARG A HB3  1 
ATOM   3997 H  HG2  . ARG A 1 250 ? -0.09196  -7.48748  0.11644  1.000 17.26637 ? 273 ARG A HG2  1 
ATOM   3998 H  HG3  . ARG A 1 250 ? 0.92623   -8.64634  -0.26532 1.000 17.26637 ? 273 ARG A HG3  1 
ATOM   3999 H  HD2  . ARG A 1 250 ? -1.52431  -8.12151  -1.57708 1.000 19.54695 ? 273 ARG A HD2  1 
ATOM   4000 H  HD3  . ARG A 1 250 ? -0.07848  -7.94506  -2.21258 1.000 19.54695 ? 273 ARG A HD3  1 
ATOM   4001 H  HE   . ARG A 1 250 ? -1.41613  -10.27062 -2.01775 1.000 21.69753 ? 273 ARG A HE   1 
ATOM   4002 H  HH11 . ARG A 1 250 ? 1.58363   -9.02265  -2.67478 1.000 24.52788 ? 273 ARG A HH11 1 
ATOM   4003 H  HH12 . ARG A 1 250 ? 2.08950   -10.21959 -3.40296 1.000 24.52788 ? 273 ARG A HH12 1 
ATOM   4004 H  HH21 . ARG A 1 250 ? -0.62704  -12.05616 -3.13290 1.000 26.13497 ? 273 ARG A HH21 1 
ATOM   4005 H  HH22 . ARG A 1 250 ? 0.75849   -12.04864 -3.67977 1.000 26.13497 ? 273 ARG A HH22 1 
ATOM   4006 N  N    A ARG A 1 251 ? -4.18567  -9.86587  2.00153  0.532 11.44283 ? 274 ARG A N    1 
ATOM   4007 N  N    B ARG A 1 251 ? -4.18460  -9.87160  2.00603  0.468 11.58646 ? 274 ARG A N    1 
ATOM   4008 C  CA   A ARG A 1 251 ? -4.99098  -10.87416 2.68702  0.532 11.67125 ? 274 ARG A CA   1 
ATOM   4009 C  CA   B ARG A 1 251 ? -4.96769  -10.88708 2.70469  0.468 11.81010 ? 274 ARG A CA   1 
ATOM   4010 C  C    A ARG A 1 251 ? -4.93405  -12.21129 1.96572  0.532 12.30725 ? 274 ARG A C    1 
ATOM   4011 C  C    B ARG A 1 251 ? -4.93605  -12.21797 1.96714  0.468 12.42113 ? 274 ARG A C    1 
ATOM   4012 O  O    A ARG A 1 251 ? -5.03590  -13.26706 2.60150  0.532 11.99352 ? 274 ARG A O    1 
ATOM   4013 O  O    B ARG A 1 251 ? -5.06163  -13.27786 2.59206  0.468 12.17155 ? 274 ARG A O    1 
ATOM   4014 C  CB   A ARG A 1 251 ? -6.43224  -10.38606 2.83667  0.532 13.34473 ? 274 ARG A CB   1 
ATOM   4015 C  CB   B ARG A 1 251 ? -6.39955  -10.40419 2.92314  0.468 13.08751 ? 274 ARG A CB   1 
ATOM   4016 C  CG   A ARG A 1 251 ? -6.51483  -9.13211  3.68759  0.532 14.10943 ? 274 ARG A CG   1 
ATOM   4017 C  CG   B ARG A 1 251 ? -6.47985  -9.26981  3.92893  0.468 13.51257 ? 274 ARG A CG   1 
ATOM   4018 C  CD   A ARG A 1 251 ? -7.89055  -8.48483  3.70240  0.532 17.16251 ? 274 ARG A CD   1 
ATOM   4019 C  CD   B ARG A 1 251 ? -7.88174  -8.71681  4.06190  0.468 14.76318 ? 274 ARG A CD   1 
ATOM   4020 N  NE   A ARG A 1 251 ? -7.85608  -7.27618  4.51858  0.532 19.95457 ? 274 ARG A NE   1 
ATOM   4021 N  NE   B ARG A 1 251 ? -8.27994  -8.03684  2.83696  0.468 17.36121 ? 274 ARG A NE   1 
ATOM   4022 C  CZ   A ARG A 1 251 ? -7.47396  -6.08323  4.08231  0.532 21.59472 ? 274 ARG A CZ   1 
ATOM   4023 C  CZ   B ARG A 1 251 ? -8.01797  -6.76685  2.56390  0.468 20.27532 ? 274 ARG A CZ   1 
ATOM   4024 N  NH1  A ARG A 1 251 ? -7.21495  -5.86383  2.80061  0.532 21.45726 ? 274 ARG A NH1  1 
ATOM   4025 N  NH1  B ARG A 1 251 ? -7.41191  -5.98168  3.44029  0.468 20.32085 ? 274 ARG A NH1  1 
ATOM   4026 N  NH2  A ARG A 1 251 ? -7.35129  -5.08544  4.95320  0.532 23.27453 ? 274 ARG A NH2  1 
ATOM   4027 N  NH2  B ARG A 1 251 ? -8.37040  -6.27465  1.38112  0.468 21.68231 ? 274 ARG A NH2  1 
ATOM   4028 H  H    A ARG A 1 251 ? -4.62745  -9.18726  1.71184  0.532 13.73140 ? 274 ARG A H    1 
ATOM   4029 H  H    B ARG A 1 251 ? -4.63431  -9.19891  1.71474  0.468 13.90375 ? 274 ARG A H    1 
ATOM   4030 H  HA   A ARG A 1 251 ? -4.63975  -11.00866 3.58114  0.532 14.00550 ? 274 ARG A HA   1 
ATOM   4031 H  HA   B ARG A 1 251 ? -4.58338  -11.03124 3.58357  0.468 14.17212 ? 274 ARG A HA   1 
ATOM   4032 H  HB2  A ARG A 1 251 ? -6.79390  -10.18365 1.95967  0.532 16.01367 ? 274 ARG A HB2  1 
ATOM   4033 H  HB2  B ARG A 1 251 ? -6.75913  -10.08640 2.08016  0.468 15.70502 ? 274 ARG A HB2  1 
ATOM   4034 H  HB3  A ARG A 1 251 ? -6.96172  -11.07854 3.26214  0.532 16.01367 ? 274 ARG A HB3  1 
ATOM   4035 H  HB3  B ARG A 1 251 ? -6.93549  -11.14114 3.25568  0.468 15.70502 ? 274 ARG A HB3  1 
ATOM   4036 H  HG2  A ARG A 1 251 ? -6.28721  -9.36055  4.60241  0.532 16.93131 ? 274 ARG A HG2  1 
ATOM   4037 H  HG2  B ARG A 1 251 ? -6.20084  -9.59575  4.79888  0.468 16.21509 ? 274 ARG A HG2  1 
ATOM   4038 H  HG3  A ARG A 1 251 ? -5.88606  -8.47911  3.34242  0.532 16.93131 ? 274 ARG A HG3  1 
ATOM   4039 H  HG3  B ARG A 1 251 ? -5.89757  -8.54888  3.64237  0.468 16.21509 ? 274 ARG A HG3  1 
ATOM   4040 H  HD2  A ARG A 1 251 ? -8.14986  -8.24482  2.79904  0.532 20.59501 ? 274 ARG A HD2  1 
ATOM   4041 H  HD2  B ARG A 1 251 ? -8.50300  -9.44287  4.22858  0.468 17.71581 ? 274 ARG A HD2  1 
ATOM   4042 H  HD3  A ARG A 1 251 ? -8.53822  -9.09958  4.08122  0.532 20.59501 ? 274 ARG A HD3  1 
ATOM   4043 H  HD3  B ARG A 1 251 ? -7.91186  -8.07999  4.79296  0.468 17.71581 ? 274 ARG A HD3  1 
ATOM   4044 H  HE   A ARG A 1 251 ? -8.10073  -7.34172  5.34044  0.532 23.94549 ? 274 ARG A HE   1 
ATOM   4045 H  HE   B ARG A 1 251 ? -8.71511  -8.49089  2.25040  0.468 20.83346 ? 274 ARG A HE   1 
ATOM   4046 H  HH11 A ARG A 1 251 ? -7.29340  -6.50293  2.23052  0.532 25.74872 ? 274 ARG A HH11 1 
ATOM   4047 H  HH11 B ARG A 1 251 ? -7.17867  -6.29297  4.20730  0.468 24.38503 ? 274 ARG A HH11 1 
ATOM   4048 H  HH12 A ARG A 1 251 ? -6.96850  -5.08242  2.53935  0.532 25.74872 ? 274 ARG A HH12 1 
ATOM   4049 H  HH12 B ARG A 1 251 ? -7.25136  -5.16022  3.24272  0.468 24.38503 ? 274 ARG A HH12 1 
ATOM   4050 H  HH21 A ARG A 1 251 ? -7.51893  -5.21863  5.78613  0.532 27.92944 ? 274 ARG A HH21 1 
ATOM   4051 H  HH21 B ARG A 1 251 ? -8.76278  -6.77866  0.80525  0.468 26.01877 ? 274 ARG A HH21 1 
ATOM   4052 H  HH22 A ARG A 1 251 ? -7.10434  -4.30710  4.68339  0.532 27.92944 ? 274 ARG A HH22 1 
ATOM   4053 H  HH22 B ARG A 1 251 ? -8.20613  -5.45208  1.19143  0.468 26.01877 ? 274 ARG A HH22 1 
ATOM   4054 N  N    . ASP A 1 252 ? -4.74473  -12.18575 0.64781  1.000 13.24260 ? 275 ASP A N    1 
ATOM   4055 C  CA   . ASP A 1 252 ? -4.63482  -13.42030 -0.10703 1.000 13.62812 ? 275 ASP A CA   1 
ATOM   4056 C  C    . ASP A 1 252 ? -3.45238  -14.26455 0.34725  1.000 12.73240 ? 275 ASP A C    1 
ATOM   4057 O  O    . ASP A 1 252 ? -3.49486  -15.49090 0.22411  1.000 12.92984 ? 275 ASP A O    1 
ATOM   4058 C  CB   . ASP A 1 252 ? -4.48573  -13.07965 -1.59652 1.000 15.58808 ? 275 ASP A CB   1 
ATOM   4059 C  CG   . ASP A 1 252 ? -3.21460  -12.29840 -1.89026 1.000 17.90217 ? 275 ASP A CG   1 
ATOM   4060 O  OD1  . ASP A 1 252 ? -3.03907  -11.19525 -1.33804 1.000 16.40100 ? 275 ASP A OD1  1 
ATOM   4061 O  OD2  . ASP A 1 252 ? -2.37599  -12.79447 -2.67777 1.000 22.50365 ? 275 ASP A OD2  1 
ATOM   4062 H  H    . ASP A 1 252 ? -4.67798  -11.46897 0.17732  1.000 15.89112 ? 275 ASP A H    1 
ATOM   4063 H  HA   . ASP A 1 252 ? -5.43982  -13.94494 0.02569  1.000 16.35375 ? 275 ASP A HA   1 
ATOM   4064 H  HB2  . ASP A 1 252 ? -4.45834  -13.90284 -2.10888 1.000 18.70569 ? 275 ASP A HB2  1 
ATOM   4065 H  HB3  . ASP A 1 252 ? -5.24197  -12.54014 -1.87567 1.000 18.70569 ? 275 ASP A HB3  1 
ATOM   4066 N  N    . VAL A 1 253 ? -2.37623  -13.63575 0.83490  1.000 12.01116 ? 276 VAL A N    1 
ATOM   4067 C  CA   . VAL A 1 253 ? -1.23030  -14.40136 1.31043  1.000 12.27553 ? 276 VAL A CA   1 
ATOM   4068 C  C    . VAL A 1 253 ? -1.60952  -15.18711 2.55200  1.000 10.84638 ? 276 VAL A C    1 
ATOM   4069 O  O    . VAL A 1 253 ? -1.18553  -16.33197 2.73589  1.000 11.80655 ? 276 VAL A O    1 
ATOM   4070 C  CB   . VAL A 1 253 ? -0.04557  -13.45413 1.56966  1.000 12.38023 ? 276 VAL A CB   1 
ATOM   4071 C  CG1  . VAL A 1 253 ? 1.06892   -14.14426 2.32449  1.000 12.31355 ? 276 VAL A CG1  1 
ATOM   4072 C  CG2  . VAL A 1 253 ? 0.47526   -12.88755 0.25717  1.000 14.33645 ? 276 VAL A CG2  1 
ATOM   4073 H  H    . VAL A 1 253 ? -2.29016  -12.78243 0.89839  1.000 14.41339 ? 276 VAL A H    1 
ATOM   4074 H  HA   . VAL A 1 253 ? -0.96283  -15.03635 0.62768  1.000 14.73064 ? 276 VAL A HA   1 
ATOM   4075 H  HB   . VAL A 1 253 ? -0.36135  -12.72317 2.12364  1.000 14.85628 ? 276 VAL A HB   1 
ATOM   4076 H  HG11 . VAL A 1 253 ? 1.85518   -13.57626 2.31577  1.000 14.77627 ? 276 VAL A HG11 1 
ATOM   4077 H  HG12 . VAL A 1 253 ? 0.78279   -14.29904 3.23831  1.000 14.77627 ? 276 VAL A HG12 1 
ATOM   4078 H  HG13 . VAL A 1 253 ? 1.26683   -14.98973 1.89214  1.000 14.77627 ? 276 VAL A HG13 1 
ATOM   4079 H  HG21 . VAL A 1 253 ? 1.17228   -12.24026 0.44710  1.000 17.20374 ? 276 VAL A HG21 1 
ATOM   4080 H  HG22 . VAL A 1 253 ? 0.83373   -13.61183 -0.27933 1.000 17.20374 ? 276 VAL A HG22 1 
ATOM   4081 H  HG23 . VAL A 1 253 ? -0.25592  -12.45777 -0.21354 1.000 17.20374 ? 276 VAL A HG23 1 
ATOM   4082 N  N    . LEU A 1 254 ? -2.40053  -14.57436 3.43060  1.000 10.01908 ? 277 LEU A N    1 
ATOM   4083 C  CA   . LEU A 1 254 ? -2.84348  -15.27816 4.62759  1.000 10.17627 ? 277 LEU A CA   1 
ATOM   4084 C  C    . LEU A 1 254 ? -3.76739  -16.42898 4.25821  1.000 10.21505 ? 277 LEU A C    1 
ATOM   4085 O  O    . LEU A 1 254 ? -3.67027  -17.51367 4.82668  1.000 10.24272 ? 277 LEU A O    1 
ATOM   4086 C  CB   . LEU A 1 254 ? -3.56196  -14.31238 5.56800  1.000 10.75803 ? 277 LEU A CB   1 
ATOM   4087 C  CG   . LEU A 1 254 ? -2.80627  -13.03442 5.91158  1.000 9.80786  ? 277 LEU A CG   1 
ATOM   4088 C  CD1  . LEU A 1 254 ? -3.55588  -12.28423 7.01131  1.000 10.09136 ? 277 LEU A CD1  1 
ATOM   4089 C  CD2  . LEU A 1 254 ? -1.36583  -13.29482 6.30968  1.000 10.37118 ? 277 LEU A CD2  1 
ATOM   4090 H  H    . LEU A 1 254 ? -2.68890  -13.76742 3.35792  1.000 12.02289 ? 277 LEU A H    1 
ATOM   4091 H  HA   . LEU A 1 254 ? -2.06903  -15.63259 5.09181  1.000 12.21152 ? 277 LEU A HA   1 
ATOM   4092 H  HB2  . LEU A 1 254 ? -4.39777  -14.04955 5.15177  1.000 12.90963 ? 277 LEU A HB2  1 
ATOM   4093 H  HB3  . LEU A 1 254 ? -3.73788  -14.77582 6.40177  1.000 12.90963 ? 277 LEU A HB3  1 
ATOM   4094 H  HG   . LEU A 1 254 ? -2.76203  -12.47900 5.11756  1.000 11.76944 ? 277 LEU A HG   1 
ATOM   4095 H  HD11 . LEU A 1 254 ? -3.04421  -11.49975 7.26366  1.000 12.10963 ? 277 LEU A HD11 1 
ATOM   4096 H  HD12 . LEU A 1 254 ? -4.42586  -12.01768 6.67519  1.000 12.10963 ? 277 LEU A HD12 1 
ATOM   4097 H  HD13 . LEU A 1 254 ? -3.66241  -12.87007 7.77704  1.000 12.10963 ? 277 LEU A HD13 1 
ATOM   4098 H  HD21 . LEU A 1 254 ? -0.95104  -12.45495 6.56162  1.000 12.44542 ? 277 LEU A HD21 1 
ATOM   4099 H  HD22 . LEU A 1 254 ? -1.35175  -13.90899 7.06035  1.000 12.44542 ? 277 LEU A HD22 1 
ATOM   4100 H  HD23 . LEU A 1 254 ? -0.89507  -13.68316 5.55570  1.000 12.44542 ? 277 LEU A HD23 1 
ATOM   4101 N  N    . ALA A 1 255 ? -4.69625  -16.20083 3.31937  1.000 10.58130 ? 278 ALA A N    1 
ATOM   4102 C  CA   . ALA A 1 255 ? -5.56893  -17.27515 2.85922  1.000 10.93430 ? 278 ALA A CA   1 
ATOM   4103 C  C    . ALA A 1 255 ? -4.75779  -18.42955 2.28498  1.000 11.20154 ? 278 ALA A C    1 
ATOM   4104 O  O    . ALA A 1 255 ? -5.03845  -19.60493 2.55899  1.000 11.84067 ? 278 ALA A O    1 
ATOM   4105 C  CB   . ALA A 1 255 ? -6.53076  -16.72296 1.81404  1.000 11.06366 ? 278 ALA A CB   1 
ATOM   4106 H  H    . ALA A 1 255 ? -4.83607  -15.44147 2.94067  1.000 12.69755 ? 278 ALA A H    1 
ATOM   4107 H  HA   . ALA A 1 255 ? -6.08554  -17.61739 3.60547  1.000 13.12116 ? 278 ALA A HA   1 
ATOM   4108 H  HB1  . ALA A 1 255 ? -7.11493  -17.43684 1.51400  1.000 13.27639 ? 278 ALA A HB1  1 
ATOM   4109 H  HB2  . ALA A 1 255 ? -7.05581  -16.01141 2.21269  1.000 13.27639 ? 278 ALA A HB2  1 
ATOM   4110 H  HB3  . ALA A 1 255 ? -6.01949  -16.37735 1.06568  1.000 13.27639 ? 278 ALA A HB3  1 
ATOM   4111 N  N    . SER A 1 256 ? -3.73954  -18.11166 1.48528  1.000 11.07495 ? 279 SER A N    1 
ATOM   4112 C  CA   . SER A 1 256 ? -2.89906  -19.15231 0.89656  1.000 12.06542 ? 279 SER A CA   1 
ATOM   4113 C  C    . SER A 1 256 ? -2.12722  -19.91646 1.96843  1.000 11.93213 ? 279 SER A C    1 
ATOM   4114 O  O    . SER A 1 256 ? -1.99762  -21.14309 1.88886  1.000 12.27957 ? 279 SER A O    1 
ATOM   4115 C  CB   . SER A 1 256 ? -1.92669  -18.51392 -0.09299 1.000 14.41590 ? 279 SER A CB   1 
ATOM   4116 O  OG   . SER A 1 256 ? -2.58689  -18.00604 -1.22840 1.000 18.47274 ? 279 SER A OG   1 
ATOM   4117 H  H    . SER A 1 256 ? -3.51612  -17.30965 1.26971  1.000 13.28993 ? 279 SER A H    1 
ATOM   4118 H  HA   . SER A 1 256 ? -3.46238  -19.78480 0.42378  1.000 14.47850 ? 279 SER A HA   1 
ATOM   4119 H  HB2  . SER A 1 256 ? -1.46524  -17.78506 0.35055  1.000 17.29908 ? 279 SER A HB2  1 
ATOM   4120 H  HB3  . SER A 1 256 ? -1.28809  -19.18571 -0.37898 1.000 17.29908 ? 279 SER A HB3  1 
ATOM   4121 H  HG   . SER A 1 256 ? -3.06583  -17.35044 -1.01298 1.000 22.16729 ? 279 SER A HG   1 
ATOM   4122 N  N    . ALA A 1 257 ? -1.59371  -19.20646 2.97129  1.000 12.00884 ? 280 ALA A N    1 
ATOM   4123 C  CA   . ALA A 1 257 ? -0.88968  -19.88936 4.05355  1.000 11.70673 ? 280 ALA A CA   1 
ATOM   4124 C  C    . ALA A 1 257 ? -1.83703  -20.83284 4.78827  1.000 11.00869 ? 280 ALA A C    1 
ATOM   4125 O  O    . ALA A 1 257 ? -1.47174  -21.96832 5.12688  1.000 12.23529 ? 280 ALA A O    1 
ATOM   4126 C  CB   . ALA A 1 257 ? -0.29424  -18.86282 5.01626  1.000 12.21199 ? 280 ALA A CB   1 
ATOM   4127 H  H    . ALA A 1 257 ? -1.62641  -18.35014 3.04380  1.000 14.41061 ? 280 ALA A H    1 
ATOM   4128 H  HA   . ALA A 1 257 ? -0.15782  -20.41047 3.68786  1.000 14.04808 ? 280 ALA A HA   1 
ATOM   4129 H  HB1  . ALA A 1 257 ? 0.16021   -19.33004 5.73465  1.000 14.65439 ? 280 ALA A HB1  1 
ATOM   4130 H  HB2  . ALA A 1 257 ? 0.33596   -18.30547 4.53345  1.000 14.65439 ? 280 ALA A HB2  1 
ATOM   4131 H  HB3  . ALA A 1 257 ? -1.00973  -18.31652 5.37755  1.000 14.65439 ? 280 ALA A HB3  1 
ATOM   4132 N  N    . ALA A 1 258 ? -3.07267  -20.38605 5.02635  1.000 11.09738 ? 281 ALA A N    1 
ATOM   4133 C  CA   . ALA A 1 258 ? -4.04350  -21.21448 5.72990  1.000 10.27298 ? 281 ALA A CA   1 
ATOM   4134 C  C    . ALA A 1 258 ? -4.37437  -22.45791 4.92391  1.000 10.92655 ? 281 ALA A C    1 
ATOM   4135 O  O    . ALA A 1 258 ? -4.48223  -23.55870 5.47919  1.000 12.21108 ? 281 ALA A O    1 
ATOM   4136 C  CB   . ALA A 1 258 ? -5.31573  -20.41574 6.01999  1.000 11.20387 ? 281 ALA A CB   1 
ATOM   4137 H  H    . ALA A 1 258 ? -3.36883  -19.61342 4.79198  1.000 13.31685 ? 281 ALA A H    1 
ATOM   4138 H  HA   . ALA A 1 258 ? -3.66384  -21.48730 6.57980  1.000 12.32758 ? 281 ALA A HA   1 
ATOM   4139 H  HB1  . ALA A 1 258 ? -5.93105  -20.97310 6.52160  1.000 13.44464 ? 281 ALA A HB1  1 
ATOM   4140 H  HB2  . ALA A 1 258 ? -5.08366  -19.62955 6.53859  1.000 13.44464 ? 281 ALA A HB2  1 
ATOM   4141 H  HB3  . ALA A 1 258 ? -5.72029  -20.14995 5.17940  1.000 13.44464 ? 281 ALA A HB3  1 
ATOM   4142 N  N    . LYS A 1 259 ? -4.53547  -22.30133 3.61113  1.000 11.79290 ? 282 LYS A N    1 
ATOM   4143 C  CA   . LYS A 1 259 ? -4.80204  -23.45486 2.76195  1.000 13.22591 ? 282 LYS A CA   1 
ATOM   4144 C  C    . LYS A 1 259 ? -3.62553  -24.42815 2.77754  1.000 13.13815 ? 282 LYS A C    1 
ATOM   4145 O  O    . LYS A 1 259 ? -3.81262  -25.64861 2.86620  1.000 13.92460 ? 282 LYS A O    1 
ATOM   4146 C  CB   . LYS A 1 259 ? -5.11663  -22.96929 1.34523  1.000 14.52049 ? 282 LYS A CB   1 
ATOM   4147 C  CG   . LYS A 1 259 ? -5.38840  -24.09612 0.37005  1.000 18.49361 ? 282 LYS A CG   1 
ATOM   4148 C  CD   . LYS A 1 259 ? -5.76335  -23.55943 -0.99661 1.000 25.16582 ? 282 LYS A CD   1 
ATOM   4149 C  CE   . LYS A 1 259 ? -6.13467  -24.71400 -1.92882 1.000 31.77480 ? 282 LYS A CE   1 
ATOM   4150 N  NZ   . LYS A 1 259 ? -6.69870  -24.26584 -3.21793 1.000 37.21707 ? 282 LYS A NZ   1 
ATOM   4151 H  H    . LYS A 1 259 ? -4.49569  -21.54970 3.19511  1.000 14.15148 ? 282 LYS A H    1 
ATOM   4152 H  HA   . LYS A 1 259 ? -5.57626  -23.93854 3.08988  1.000 15.87109 ? 282 LYS A HA   1 
ATOM   4153 H  HB2  . LYS A 1 259 ? -5.90500  -22.40496 1.37534  1.000 17.42458 ? 282 LYS A HB2  1 
ATOM   4154 H  HB3  . LYS A 1 259 ? -4.35904  -22.46339 1.01202  1.000 17.42458 ? 282 LYS A HB3  1 
ATOM   4155 H  HG2  . LYS A 1 259 ? -4.59143  -24.64114 0.27682  1.000 22.19233 ? 282 LYS A HG2  1 
ATOM   4156 H  HG3  . LYS A 1 259 ? -6.12352  -24.63686 0.69884  1.000 22.19233 ? 282 LYS A HG3  1 
ATOM   4157 H  HD2  . LYS A 1 259 ? -6.52670  -22.96630 -0.91675 1.000 30.19898 ? 282 LYS A HD2  1 
ATOM   4158 H  HD3  . LYS A 1 259 ? -5.01034  -23.08153 -1.37803 1.000 30.19898 ? 282 LYS A HD3  1 
ATOM   4159 H  HE2  . LYS A 1 259 ? -5.33795  -25.23412 -2.11757 1.000 38.12976 ? 282 LYS A HE2  1 
ATOM   4160 H  HE3  . LYS A 1 259 ? -6.79804  -25.27022 -1.49127 1.000 38.12976 ? 282 LYS A HE3  1 
ATOM   4161 H  HZ1  . LYS A 1 259 ? -7.00973  -24.96435 -3.67338 1.000 44.66048 ? 282 LYS A HZ1  1 
ATOM   4162 H  HZ2  . LYS A 1 259 ? -7.36534  -23.69353 -3.07599 1.000 44.66048 ? 282 LYS A HZ2  1 
ATOM   4163 H  HZ3  . LYS A 1 259 ? -6.06981  -23.86251 -3.70158 1.000 44.66048 ? 282 LYS A HZ3  1 
ATOM   4164 N  N    . ILE A 1 260 ? -2.40419  -23.90529 2.70385  1.000 12.94299 ? 283 ILE A N    1 
ATOM   4165 C  CA   . ILE A 1 260 ? -1.22501  -24.76639 2.70240  1.000 13.74930 ? 283 ILE A CA   1 
ATOM   4166 C  C    . ILE A 1 260 ? -1.14915  -25.60114 3.97819  1.000 13.01822 ? 283 ILE A C    1 
ATOM   4167 O  O    . ILE A 1 260 ? -0.90499  -26.81269 3.93143  1.000 14.69649 ? 283 ILE A O    1 
ATOM   4168 C  CB   . ILE A 1 260 ? 0.04830   -23.92884 2.49025  1.000 14.15942 ? 283 ILE A CB   1 
ATOM   4169 C  CG1  . ILE A 1 260 ? 0.13668   -23.45367 1.03480  1.000 14.71306 ? 283 ILE A CG1  1 
ATOM   4170 C  CG2  . ILE A 1 260 ? 1.30151   -24.70616 2.85639  1.000 15.31506 ? 283 ILE A CG2  1 
ATOM   4171 C  CD1  . ILE A 1 260 ? 1.11251   -22.33626 0.83580  1.000 15.16968 ? 283 ILE A CD1  1 
ATOM   4172 H  H    . ILE A 1 260 ? -2.23203  -23.06416 2.65430  1.000 15.53159 ? 283 ILE A H    1 
ATOM   4173 H  HA   . ILE A 1 260 ? -1.30597  -25.38637 1.96081  1.000 16.49916 ? 283 ILE A HA   1 
ATOM   4174 H  HB   . ILE A 1 260 ? -0.01145  -23.15992 3.07855  1.000 16.99130 ? 283 ILE A HB   1 
ATOM   4175 H  HG12 . ILE A 1 260 ? 0.41726   -24.19712 0.47851  1.000 17.65567 ? 283 ILE A HG12 1 
ATOM   4176 H  HG13 . ILE A 1 260 ? -0.73706  -23.14009 0.75350  1.000 17.65567 ? 283 ILE A HG13 1 
ATOM   4177 H  HG21 . ILE A 1 260 ? 2.07817   -24.22437 2.53147  1.000 18.37807 ? 283 ILE A HG21 1 
ATOM   4178 H  HG22 . ILE A 1 260 ? 1.34728   -24.79522 3.82121  1.000 18.37807 ? 283 ILE A HG22 1 
ATOM   4179 H  HG23 . ILE A 1 260 ? 1.26046   -25.58354 2.44480  1.000 18.37807 ? 283 ILE A HG23 1 
ATOM   4180 H  HD11 . ILE A 1 260 ? 1.07743   -22.04738 -0.08952 1.000 18.20362 ? 283 ILE A HD11 1 
ATOM   4181 H  HD12 . ILE A 1 260 ? 0.87390   -21.60059 1.42127  1.000 18.20362 ? 283 ILE A HD12 1 
ATOM   4182 H  HD13 . ILE A 1 260 ? 2.00385   -22.65353 1.04971  1.000 18.20362 ? 283 ILE A HD13 1 
ATOM   4183 N  N    . VAL A 1 261 ? -1.32690  -24.96533 5.14109  1.000 13.25023 ? 284 VAL A N    1 
ATOM   4184 C  CA   . VAL A 1 261 ? -1.07656  -25.67758 6.39112  1.000 13.94979 ? 284 VAL A CA   1 
ATOM   4185 C  C    . VAL A 1 261 ? -2.23644  -26.56282 6.82035  1.000 14.80543 ? 284 VAL A C    1 
ATOM   4186 O  O    . VAL A 1 261 ? -2.05317  -27.41390 7.69577  1.000 17.20115 ? 284 VAL A O    1 
ATOM   4187 C  CB   . VAL A 1 261 ? -0.66142  -24.76249 7.55641  1.000 13.66793 ? 284 VAL A CB   1 
ATOM   4188 C  CG1  . VAL A 1 261 ? 0.59574   -24.00208 7.17142  1.000 14.09932 ? 284 VAL A CG1  1 
ATOM   4189 C  CG2  . VAL A 1 261 ? -1.77702  -23.82802 7.97693  1.000 13.49341 ? 284 VAL A CG2  1 
ATOM   4190 H  H    . VAL A 1 261 ? -1.58332  -24.14904 5.22782  1.000 15.90028 ? 284 VAL A H    1 
ATOM   4191 H  HA   . VAL A 1 261 ? -0.31346  -26.24611 6.20310  1.000 16.73975 ? 284 VAL A HA   1 
ATOM   4192 H  HB   . VAL A 1 261 ? -0.47126  -25.30931 8.33469  1.000 16.40151 ? 284 VAL A HB   1 
ATOM   4193 H  HG11 . VAL A 1 261 ? 0.92256   -23.51916 7.94659  1.000 16.91919 ? 284 VAL A HG11 1 
ATOM   4194 H  HG12 . VAL A 1 261 ? 1.26651   -24.63377 6.86823  1.000 16.91919 ? 284 VAL A HG12 1 
ATOM   4195 H  HG13 . VAL A 1 261 ? 0.38231   -23.37899 6.45931  1.000 16.91919 ? 284 VAL A HG13 1 
ATOM   4196 H  HG21 . VAL A 1 261 ? -1.43723  -23.21020 8.64307  1.000 16.19210 ? 284 VAL A HG21 1 
ATOM   4197 H  HG22 . VAL A 1 261 ? -2.08844  -23.33815 7.19979  1.000 16.19210 ? 284 VAL A HG22 1 
ATOM   4198 H  HG23 . VAL A 1 261 ? -2.50313  -24.35126 8.35094  1.000 16.19210 ? 284 VAL A HG23 1 
ATOM   4199 N  N    . THR A 1 262 ? -3.42868  -26.39123 6.24983  1.000 14.82144 ? 285 THR A N    1 
ATOM   4200 C  CA   . THR A 1 262 ? -4.56157  -27.22896 6.61726  1.000 17.18428 ? 285 THR A CA   1 
ATOM   4201 C  C    . THR A 1 262 ? -4.88247  -28.26683 5.55693  1.000 20.73676 ? 285 THR A C    1 
ATOM   4202 O  O    . THR A 1 262 ? -5.82303  -29.04317 5.73329  1.000 22.39197 ? 285 THR A O    1 
ATOM   4203 C  CB   . THR A 1 262 ? -5.81849  -26.39297 6.89923  1.000 16.07099 ? 285 THR A CB   1 
ATOM   4204 O  OG1  . THR A 1 262 ? -6.20151  -25.66748 5.72507  1.000 15.73451 ? 285 THR A OG1  1 
ATOM   4205 C  CG2  . THR A 1 262 ? -5.58869  -25.44238 8.05333  1.000 16.69529 ? 285 THR A CG2  1 
ATOM   4206 H  H    . THR A 1 262 ? -3.60171  -25.79864 5.65109  1.000 17.78573 ? 285 THR A H    1 
ATOM   4207 H  HA   . THR A 1 262 ? -4.33396  -27.68267 7.44385  1.000 20.62113 ? 285 THR A HA   1 
ATOM   4208 H  HB   . THR A 1 262 ? -6.54580  -26.98476 7.14764  1.000 19.28518 ? 285 THR A HB   1 
ATOM   4209 H  HG1  . THR A 1 262 ? -5.65433  -25.04700 5.57948  1.000 18.88142 ? 285 THR A HG1  1 
ATOM   4210 H  HG21 . THR A 1 262 ? -6.39350  -24.92905 8.22561  1.000 20.03435 ? 285 THR A HG21 1 
ATOM   4211 H  HG22 . THR A 1 262 ? -5.35609  -25.94074 8.85235  1.000 20.03435 ? 285 THR A HG22 1 
ATOM   4212 H  HG23 . THR A 1 262 ? -4.86529  -24.83193 7.84133  1.000 20.03435 ? 285 THR A HG23 1 
ATOM   4213 N  N    . ASP A 1 263 ? -4.14060  -28.28215 4.45705  1.000 23.24911 ? 286 ASP A N    1 
ATOM   4214 C  CA   . ASP A 1 263 ? -4.36891  -29.27882 3.41943  1.000 29.14710 ? 286 ASP A CA   1 
ATOM   4215 C  C    . ASP A 1 263 ? -4.29086  -30.66856 4.03818  1.000 32.69708 ? 286 ASP A C    1 
ATOM   4216 O  O    . ASP A 1 263 ? -3.27671  -31.03198 4.64201  1.000 33.67129 ? 286 ASP A O    1 
ATOM   4217 C  CB   . ASP A 1 263 ? -3.31684  -29.12494 2.32817  1.000 33.75375 ? 286 ASP A CB   1 
ATOM   4218 C  CG   . ASP A 1 263 ? -3.49960  -30.12010 1.19836  1.000 38.16017 ? 286 ASP A CG   1 
ATOM   4219 O  OD1  . ASP A 1 263 ? -4.62502  -30.63335 1.02416  1.000 39.21740 ? 286 ASP A OD1  1 
ATOM   4220 O  OD2  . ASP A 1 263 ? -2.50910  -30.39250 0.48805  1.000 40.61226 ? 286 ASP A OD2  1 
ATOM   4221 H  H    . ASP A 1 263 ? -3.50294  -27.73041 4.28797  1.000 27.89893 ? 286 ASP A H    1 
ATOM   4222 H  HA   . ASP A 1 263 ? -5.24417  -29.15657 3.01957  1.000 34.97652 ? 286 ASP A HA   1 
ATOM   4223 H  HB2  . ASP A 1 263 ? -3.37623  -28.23172 1.95461  1.000 40.50450 ? 286 ASP A HB2  1 
ATOM   4224 H  HB3  . ASP A 1 263 ? -2.43785  -29.26562 2.71350  1.000 40.50450 ? 286 ASP A HB3  1 
ATOM   4225 N  N    . GLY A 1 264 ? -5.37062  -31.43507 3.91302  1.000 35.70480 ? 287 GLY A N    1 
ATOM   4226 C  CA   . GLY A 1 264 ? -5.43892  -32.76912 4.46257  1.000 38.57385 ? 287 GLY A CA   1 
ATOM   4227 C  C    . GLY A 1 264 ? -6.18059  -32.88665 5.77697  1.000 40.76405 ? 287 GLY A C    1 
ATOM   4228 O  O    . GLY A 1 264 ? -6.48462  -34.01209 6.19224  1.000 41.61305 ? 287 GLY A O    1 
ATOM   4229 H  H    . GLY A 1 264 ? -6.08727  -31.19249 3.50416  1.000 42.84576 ? 287 GLY A H    1 
ATOM   4230 H  HA2  . GLY A 1 264 ? -5.88315  -33.34559 3.82128  1.000 46.28862 ? 287 GLY A HA2  1 
ATOM   4231 H  HA3  . GLY A 1 264 ? -4.53530  -33.09196 4.60450  1.000 46.28862 ? 287 GLY A HA3  1 
ATOM   4232 N  N    . LEU A 1 265 ? -6.48498  -31.77369 6.43905  1.000 40.77014 ? 288 LEU A N    1 
ATOM   4233 C  CA   . LEU A 1 265 ? -7.16352  -31.82586 7.73189  1.000 41.59476 ? 288 LEU A CA   1 
ATOM   4234 C  C    . LEU A 1 265 ? -8.68332  -31.72842 7.59665  1.000 42.22625 ? 288 LEU A C    1 
ATOM   4235 O  O    . LEU A 1 265 ? -9.22243  -31.50297 6.51063  1.000 41.60743 ? 288 LEU A O    1 
ATOM   4236 C  CB   . LEU A 1 265 ? -6.67684  -30.69839 8.64663  1.000 41.12968 ? 288 LEU A CB   1 
ATOM   4237 C  CG   . LEU A 1 265 ? -5.18228  -30.60765 8.94175  1.000 40.50790 ? 288 LEU A CG   1 
ATOM   4238 C  CD1  . LEU A 1 265 ? -4.89486  -29.37777 9.79623  1.000 40.22567 ? 288 LEU A CD1  1 
ATOM   4239 C  CD2  . LEU A 1 265 ? -4.68027  -31.86603 9.62635  1.000 40.49623 ? 288 LEU A CD2  1 
ATOM   4240 O  OXT  . LEU A 1 265 ? -9.40819  -31.86471 8.58814  1.000 42.17638 ? 288 LEU A OXT  1 
ATOM   4241 H  H    . LEU A 1 265 ? -6.31004  -30.97848 6.16222  1.000 48.92417 ? 288 LEU A H    1 
ATOM   4242 H  HA   . LEU A 1 265 ? -6.95119  -32.68138 8.13673  1.000 49.91371 ? 288 LEU A HA   1 
ATOM   4243 H  HB2  . LEU A 1 265 ? -6.93116  -29.85669 8.23703  1.000 49.35562 ? 288 LEU A HB2  1 
ATOM   4244 H  HB3  . LEU A 1 265 ? -7.12362  -30.79962 9.50164  1.000 49.35562 ? 288 LEU A HB3  1 
ATOM   4245 H  HG   . LEU A 1 265 ? -4.69992  -30.52296 8.10446  1.000 48.60948 ? 288 LEU A HG   1 
ATOM   4246 H  HD11 . LEU A 1 265 ? -3.93522  -29.24592 9.84724  1.000 48.27081 ? 288 LEU A HD11 1 
ATOM   4247 H  HD12 . LEU A 1 265 ? -5.31375  -28.60428 9.38741  1.000 48.27081 ? 288 LEU A HD12 1 
ATOM   4248 H  HD13 . LEU A 1 265 ? -5.25704  -29.51901 10.68493 1.000 48.27081 ? 288 LEU A HD13 1 
ATOM   4249 H  HD21 . LEU A 1 265 ? -3.78297  -31.70795 9.95916  1.000 48.59547 ? 288 LEU A HD21 1 
ATOM   4250 H  HD22 . LEU A 1 265 ? -5.27294  -32.08262 10.36306 1.000 48.59547 ? 288 LEU A HD22 1 
ATOM   4251 H  HD23 . LEU A 1 265 ? -4.67159  -32.59291 8.98411  1.000 48.59547 ? 288 LEU A HD23 1 
HETATM 4252 C  C12  A XR9 B 2 .   ? -6.19791  -1.31371  12.61103 0.386 10.88745 ? 301 XR9 A C12  1 
HETATM 4253 C  C12  B XR9 B 2 .   ? -7.31108  -3.21538  11.92529 0.614 12.49115 ? 301 XR9 A C12  1 
HETATM 4254 C  C11  A XR9 B 2 .   ? -5.35069  -0.24729  12.93880 0.386 12.18996 ? 301 XR9 A C11  1 
HETATM 4255 C  C11  B XR9 B 2 .   ? -7.72432  -4.35674  11.22452 0.614 12.31584 ? 301 XR9 A C11  1 
HETATM 4256 C  C9   A XR9 B 2 .   ? -6.60887  1.24571   11.54444 0.386 13.00496 ? 301 XR9 A C9   1 
HETATM 4257 C  C9   B XR9 B 2 .   ? -9.48656  -3.12085  10.16228 0.614 16.19236 ? 301 XR9 A C9   1 
HETATM 4258 C  C7   A XR9 B 2 .   ? -7.25194  -1.05831  11.73545 0.386 12.73716 ? 301 XR9 A C7   1 
HETATM 4259 C  C7   B XR9 B 2 .   ? -8.01542  -2.03498  11.71301 0.614 13.72014 ? 301 XR9 A C7   1 
HETATM 4260 C  C4   A XR9 B 2 .   ? -8.06206  -2.30167  11.45096 0.386 14.70319 ? 301 XR9 A C4   1 
HETATM 4261 C  C4   B XR9 B 2 .   ? -7.45292  -0.88986  12.52797 0.614 14.34894 ? 301 XR9 A C4   1 
HETATM 4262 N  N6   A XR9 B 2 .   ? -7.94826  -2.83675  8.88751  0.386 20.41830 ? 301 XR9 A N6   1 
HETATM 4263 N  N6   B XR9 B 2 .   ? -6.77073  1.18499   11.08780 0.614 19.93903 ? 301 XR9 A N6   1 
HETATM 4264 B  B2   A XR9 B 2 .   ? -6.25790  -2.82552  12.97987 0.386 10.94560 ? 301 XR9 A B2   1 
HETATM 4265 B  B2   B XR9 B 2 .   ? -6.18107  -2.91173  12.95475 0.614 10.78154 ? 301 XR9 A B2   1 
HETATM 4266 C  C10  A XR9 B 2 .   ? -5.55275  1.01680   12.41067 0.386 12.71113 ? 301 XR9 A C10  1 
HETATM 4267 C  C10  B XR9 B 2 .   ? -8.80047  -4.30903  10.35451 0.614 15.29311 ? 301 XR9 A C10  1 
HETATM 4268 C  C5   A XR9 B 2 .   ? -7.98260  -2.62100  10.00721 0.386 17.54676 ? 301 XR9 A C5   1 
HETATM 4269 C  C5   B XR9 B 2 .   ? -7.05030  0.26878   11.70152 0.614 17.30825 ? 301 XR9 A C5   1 
HETATM 4270 C  C8   A XR9 B 2 .   ? -7.46396  0.20867   11.20118 0.386 12.93515 ? 301 XR9 A C8   1 
HETATM 4271 C  C8   B XR9 B 2 .   ? -9.09739  -1.97729  10.84021 0.614 14.87839 ? 301 XR9 A C8   1 
HETATM 4272 O  O1   A XR9 B 2 .   ? -5.02498  -3.53825  12.58964 0.386 10.59314 ? 301 XR9 A O1   1 
HETATM 4273 O  O1   B XR9 B 2 .   ? -4.82584  -3.25582  12.50068 0.614 10.67003 ? 301 XR9 A O1   1 
HETATM 4274 O  O3   A XR9 B 2 .   ? -7.44027  -3.32809  12.21011 0.386 13.61578 ? 301 XR9 A O3   1 
HETATM 4275 O  O3   B XR9 B 2 .   ? -6.35504  -1.44829  13.23427 0.614 13.30770 ? 301 XR9 A O3   1 
HETATM 4276 H  H11  A XR9 B 2 .   ? -4.60491  -0.39894  13.55493 0.386 14.62795 ? 301 XR9 A H11  1 
HETATM 4277 H  H11  B XR9 B 2 .   ? -7.24391  -5.20209  11.34894 0.614 14.77901 ? 301 XR9 A H11  1 
HETATM 4278 H  H9   A XR9 B 2 .   ? -6.75281  2.14019   11.17347 0.386 15.60595 ? 301 XR9 A H9   1 
HETATM 4279 H  H9   B XR9 B 2 .   ? -10.24726 -3.08861  9.54687  0.614 19.43083 ? 301 XR9 A H9   1 
HETATM 4280 H  H4   A XR9 B 2 .   ? -8.98429  -2.19612  11.76208 0.386 17.64382 ? 301 XR9 A H4   1 
HETATM 4281 H  H4   B XR9 B 2 .   ? -8.12482  -0.60018  13.17841 0.614 17.21873 ? 301 XR9 A H4   1 
HETATM 4282 H  H10  A XR9 B 2 .   ? -4.94822  1.74862   12.65028 0.386 15.25336 ? 301 XR9 A H10  1 
HETATM 4283 H  H10  B XR9 B 2 .   ? -9.07635  -5.11665  9.87484  0.614 18.35173 ? 301 XR9 A H10  1 
HETATM 4284 H  H8   A XR9 B 2 .   ? -8.21009  0.36860   10.58786 0.386 15.52219 ? 301 XR9 A H8   1 
HETATM 4285 H  H8   B XR9 B 2 .   ? -9.58046  -1.13652  10.70533 0.614 17.85407 ? 301 XR9 A H8   1 
HETATM 4286 H  H1   A XR9 B 2 .   ? -4.53784  -2.95645  12.20661 0.386 12.71177 ? 301 XR9 A H1   1 
HETATM 4287 H  H1   B XR9 B 2 .   ? -4.70022  -2.79968  11.79452 0.614 12.80403 ? 301 XR9 A H1   1 
HETATM 4288 S  S    . DMS C 3 .   ? 11.56495  -6.59534  14.59374 1.000 53.98049 ? 302 DMS A S    1 
HETATM 4289 O  O    . DMS C 3 .   ? 10.09856  -6.60807  14.29479 1.000 53.20912 ? 302 DMS A O    1 
HETATM 4290 C  C1   . DMS C 3 .   ? 12.32805  -8.10455  13.92640 1.000 53.80803 ? 302 DMS A C1   1 
HETATM 4291 C  C2   . DMS C 3 .   ? 11.80014  -6.92361  16.36319 1.000 53.25188 ? 302 DMS A C2   1 
HETATM 4292 H  H11  . DMS C 3 .   ? 13.23674  -8.29602  14.43543 1.000 64.56964 ? 302 DMS A H11  1 
HETATM 4293 H  H12  . DMS C 3 .   ? 12.52308  -7.97510  12.89359 1.000 64.56964 ? 302 DMS A H12  1 
HETATM 4294 H  H13  . DMS C 3 .   ? 11.66947  -8.92287  14.06090 1.000 64.56964 ? 302 DMS A H13  1 
HETATM 4295 H  H21  . DMS C 3 .   ? 12.65141  -6.39785  16.71017 1.000 63.90226 ? 302 DMS A H21  1 
HETATM 4296 H  H22  . DMS C 3 .   ? 11.94148  -7.96220  16.51431 1.000 63.90226 ? 302 DMS A H22  1 
HETATM 4297 H  H23  . DMS C 3 .   ? 10.94496  -6.60261  16.89901 1.000 63.90226 ? 302 DMS A H23  1 
HETATM 4298 S  S    . SO4 D 4 .   ? 9.88322   -8.17985  29.63792 1.000 70.48424 ? 303 SO4 A S    1 
HETATM 4299 O  O1   . SO4 D 4 .   ? 9.91967   -9.58198  30.04366 1.000 70.67970 ? 303 SO4 A O1   1 
HETATM 4300 O  O2   . SO4 D 4 .   ? 9.80473   -8.07396  28.18423 1.000 71.37204 ? 303 SO4 A O2   1 
HETATM 4301 O  O3   . SO4 D 4 .   ? 11.09510  -7.50884  30.10171 1.000 69.90443 ? 303 SO4 A O3   1 
HETATM 4302 O  O4   . SO4 D 4 .   ? 8.71625   -7.53809  30.23479 1.000 71.02022 ? 303 SO4 A O4   1 
HETATM 4303 S  S    . SO4 E 4 .   ? 3.66685   7.25647   20.35023 0.679 14.99956 ? 304 SO4 A S    1 
HETATM 4304 O  O1   . SO4 E 4 .   ? 2.64891   6.26351   20.56598 0.679 13.89595 ? 304 SO4 A O1   1 
HETATM 4305 O  O2   . SO4 E 4 .   ? 3.89103   7.52877   18.93505 0.679 16.64000 ? 304 SO4 A O2   1 
HETATM 4306 O  O3   . SO4 E 4 .   ? 4.91047   6.75775   20.91637 0.679 14.72574 ? 304 SO4 A O3   1 
HETATM 4307 O  O4   . SO4 E 4 .   ? 3.24425   8.45849   21.06375 0.679 14.33615 ? 304 SO4 A O4   1 
HETATM 4308 S  S    A SO4 F 4 .   ? 13.86045  -2.30512  23.81281 0.480 77.86497 ? 305 SO4 A S    1 
HETATM 4309 S  S    B SO4 F 4 .   ? 13.68192  -2.02099  23.54645 0.520 78.37075 ? 305 SO4 A S    1 
HETATM 4310 O  O1   A SO4 F 4 .   ? 15.14230  -2.29535  23.11301 0.480 77.80659 ? 305 SO4 A O1   1 
HETATM 4311 O  O1   B SO4 F 4 .   ? 14.84928  -1.93799  22.67260 0.520 78.34911 ? 305 SO4 A O1   1 
HETATM 4312 O  O2   A SO4 F 4 .   ? 12.90692  -1.47314  23.08815 0.480 78.06087 ? 305 SO4 A O2   1 
HETATM 4313 O  O2   B SO4 F 4 .   ? 12.46748  -2.07109  22.73834 0.520 78.46943 ? 305 SO4 A O2   1 
HETATM 4314 O  O3   A SO4 F 4 .   ? 13.35128  -3.67127  23.88480 0.480 77.72977 ? 305 SO4 A O3   1 
HETATM 4315 O  O3   B SO4 F 4 .   ? 13.76954  -3.22970  24.36061 0.520 78.39085 ? 305 SO4 A O3   1 
HETATM 4316 O  O4   A SO4 F 4 .   ? 14.04038  -1.77819  25.16225 0.480 77.87275 ? 305 SO4 A O4   1 
HETATM 4317 O  O4   B SO4 F 4 .   ? 13.64255  -0.84660  24.41316 0.520 78.38576 ? 305 SO4 A O4   1 
HETATM 4318 S  S    . SO4 G 4 .   ? -16.92369 -30.32157 3.64480  1.000 74.57584 ? 306 SO4 A S    1 
HETATM 4319 O  O1   . SO4 G 4 .   ? -16.14325 -29.83724 2.50871  1.000 74.52623 ? 306 SO4 A O1   1 
HETATM 4320 O  O2   . SO4 G 4 .   ? -18.12522 -30.99647 3.16060  1.000 74.69588 ? 306 SO4 A O2   1 
HETATM 4321 O  O3   . SO4 G 4 .   ? -17.30474 -29.19429 4.48733  1.000 74.37804 ? 306 SO4 A O3   1 
HETATM 4322 O  O4   . SO4 G 4 .   ? -16.11991 -31.25918 4.42458  1.000 74.42241 ? 306 SO4 A O4   1 
HETATM 4323 CL CL   . CL  H 5 .   ? -15.78025 -25.48873 0.54645  1.000 14.63644 ? 307 CL  A CL   1 
HETATM 4324 NA NA   . NA  I 6 .   ? 1.81473   -13.36881 21.94625 1.000 15.68312 ? 308 NA  A NA   1 
HETATM 4325 NA NA   . NA  J 6 .   ? -10.28883 -15.33851 8.97303  1.000 15.19617 ? 309 NA  A NA   1 
HETATM 4326 O  O    . HOH K 7 .   ? 11.69117  -0.04431  22.69221 1.000 58.30847 ? 401 HOH A O    1 
HETATM 4327 O  O    . HOH K 7 .   ? -14.99820 8.13068   12.95430 1.000 50.77243 ? 402 HOH A O    1 
HETATM 4328 O  O    . HOH K 7 .   ? 4.82094   5.84754   22.64875 1.000 48.83571 ? 403 HOH A O    1 
HETATM 4329 O  O    . HOH K 7 .   ? -18.65794 -8.04418  34.56702 1.000 33.14634 ? 404 HOH A O    1 
HETATM 4330 O  O    . HOH K 7 .   ? 7.06039   -19.86248 -8.29167 1.000 61.21291 ? 405 HOH A O    1 
HETATM 4331 O  O    . HOH K 7 .   ? 6.91022   6.88182   20.36777 1.000 58.62664 ? 406 HOH A O    1 
HETATM 4332 O  O    . HOH K 7 .   ? -12.44346 -21.90197 32.42874 1.000 32.02148 ? 407 HOH A O    1 
HETATM 4333 O  O    A HOH K 7 .   ? -12.27034 2.12781   32.29146 0.618 28.26917 ? 408 HOH A O    1 
HETATM 4334 O  O    . HOH K 7 .   ? -3.50626  -5.15311  5.83279  1.000 35.48954 ? 409 HOH A O    1 
HETATM 4335 O  O    . HOH K 7 .   ? 5.06669   5.97365   17.53296 1.000 21.92401 ? 410 HOH A O    1 
HETATM 4336 O  O    B HOH K 7 .   ? -1.11465  -11.14628 17.63335 0.301 16.50133 ? 411 HOH A O    1 
HETATM 4337 O  O    . HOH K 7 .   ? -8.54764  -16.63424 35.19636 1.000 29.94907 ? 412 HOH A O    1 
HETATM 4338 O  O    . HOH K 7 .   ? 4.12716   -30.78609 12.43404 1.000 66.74702 ? 413 HOH A O    1 
HETATM 4339 O  O    . HOH K 7 .   ? 13.58898  -17.39036 11.46845 1.000 41.11911 ? 414 HOH A O    1 
HETATM 4340 O  O    A HOH K 7 .   ? -2.29820  -29.05575 21.49796 0.597 18.78825 ? 415 HOH A O    1 
HETATM 4341 O  O    . HOH K 7 .   ? -4.45457  -2.03070  15.80858 1.000 11.65188 ? 416 HOH A O    1 
HETATM 4342 O  O    B HOH K 7 .   ? -10.85549 -8.59339  12.19610 0.664 14.43916 ? 417 HOH A O    1 
HETATM 4343 O  O    . HOH K 7 .   ? -3.97607  -21.78271 31.28642 1.000 20.16285 ? 418 HOH A O    1 
HETATM 4344 O  O    . HOH K 7 .   ? -5.64917  -27.71225 23.52966 1.000 35.76741 ? 419 HOH A O    1 
HETATM 4345 O  O    . HOH K 7 .   ? -3.51137  -10.68182 20.53600 1.000 36.41836 ? 420 HOH A O    1 
HETATM 4346 O  O    . HOH K 7 .   ? -9.20311  11.35479  14.60617 1.000 48.71849 ? 421 HOH A O    1 
HETATM 4347 O  O    . HOH K 7 .   ? -23.80072 5.32870   23.51283 1.000 32.73514 ? 422 HOH A O    1 
HETATM 4348 O  O    . HOH K 7 .   ? -23.33766 -3.63237  27.87428 1.000 27.18645 ? 423 HOH A O    1 
HETATM 4349 O  O    . HOH K 7 .   ? 10.36907  -11.41934 28.22829 1.000 46.88905 ? 424 HOH A O    1 
HETATM 4350 O  O    . HOH K 7 .   ? 9.65605   -15.52235 34.25078 1.000 16.37764 ? 425 HOH A O    1 
HETATM 4351 O  O    . HOH K 7 .   ? -17.07445 -11.61455 32.86129 1.000 25.80078 ? 426 HOH A O    1 
HETATM 4352 O  O    . HOH K 7 .   ? 1.26703   -18.42618 26.27337 1.000 31.36501 ? 427 HOH A O    1 
HETATM 4353 O  O    . HOH K 7 .   ? -14.85548 -2.82022  10.64408 1.000 46.89346 ? 428 HOH A O    1 
HETATM 4354 O  O    . HOH K 7 .   ? -13.82807 -30.55104 5.57672  1.000 32.23374 ? 429 HOH A O    1 
HETATM 4355 O  O    . HOH K 7 .   ? -24.28874 7.08430   29.87635 1.000 15.12056 ? 430 HOH A O    1 
HETATM 4356 O  O    . HOH K 7 .   ? 11.32226  -9.59470  0.87026  1.000 26.27809 ? 431 HOH A O    1 
HETATM 4357 O  O    . HOH K 7 .   ? -8.83921  7.09459   21.67951 1.000 17.05061 ? 432 HOH A O    1 
HETATM 4358 O  O    . HOH K 7 .   ? -7.75324  11.06191  20.27058 1.000 32.53411 ? 433 HOH A O    1 
HETATM 4359 O  O    . HOH K 7 .   ? -15.33358 -20.20006 8.08615  1.000 37.53774 ? 434 HOH A O    1 
HETATM 4360 O  O    . HOH K 7 .   ? 7.91014   -3.75313  13.64126 1.000 13.70787 ? 435 HOH A O    1 
HETATM 4361 O  O    . HOH K 7 .   ? -5.15408  -16.60152 33.79224 1.000 40.37204 ? 436 HOH A O    1 
HETATM 4362 O  O    . HOH K 7 .   ? -8.28205  -30.52789 21.47830 1.000 39.30029 ? 437 HOH A O    1 
HETATM 4363 O  O    . HOH K 7 .   ? 6.80006   0.24798   14.38881 1.000 12.16983 ? 438 HOH A O    1 
HETATM 4364 O  O    . HOH K 7 .   ? 10.80529  -16.94994 28.58981 1.000 23.31872 ? 439 HOH A O    1 
HETATM 4365 O  O    . HOH K 7 .   ? -10.78006 10.22932  28.02991 1.000 50.08968 ? 440 HOH A O    1 
HETATM 4366 O  O    . HOH K 7 .   ? -14.35076 -16.34054 2.86099  1.000 25.69851 ? 441 HOH A O    1 
HETATM 4367 O  O    . HOH K 7 .   ? -18.44285 -20.27900 6.46505  1.000 44.09371 ? 442 HOH A O    1 
HETATM 4368 O  O    . HOH K 7 .   ? -10.00427 -10.16949 6.11636  1.000 21.91675 ? 443 HOH A O    1 
HETATM 4369 O  O    . HOH K 7 .   ? 6.36592   -2.25697  15.41215 1.000 12.84898 ? 444 HOH A O    1 
HETATM 4370 O  O    . HOH K 7 .   ? -1.37096  -17.27796 35.78782 1.000 20.47930 ? 445 HOH A O    1 
HETATM 4371 O  O    . HOH K 7 .   ? -23.53977 1.01180   17.63733 1.000 41.10233 ? 446 HOH A O    1 
HETATM 4372 O  O    . HOH K 7 .   ? -1.06164  6.22377   19.51723 1.000 13.64609 ? 447 HOH A O    1 
HETATM 4373 O  O    . HOH K 7 .   ? -9.24341  -11.53500 37.98152 1.000 36.20554 ? 448 HOH A O    1 
HETATM 4374 O  O    . HOH K 7 .   ? 0.09578   -29.76991 12.78113 1.000 47.86012 ? 449 HOH A O    1 
HETATM 4375 O  O    . HOH K 7 .   ? 7.21661   -4.71149  9.47778  1.000 17.26944 ? 450 HOH A O    1 
HETATM 4376 O  O    . HOH K 7 .   ? 1.61896   -3.74208  16.12698 1.000 10.38944 ? 451 HOH A O    1 
HETATM 4377 O  O    A HOH K 7 .   ? -11.55845 2.86690   29.70210 0.689 23.93062 ? 452 HOH A O    1 
HETATM 4378 O  O    . HOH K 7 .   ? 5.87992   -7.81330  -0.87466 1.000 32.64541 ? 453 HOH A O    1 
HETATM 4379 O  O    . HOH K 7 .   ? -16.37551 -21.86316 28.46012 1.000 31.54812 ? 454 HOH A O    1 
HETATM 4380 O  O    . HOH K 7 .   ? -1.16870  -22.88393 25.07314 1.000 18.57821 ? 455 HOH A O    1 
HETATM 4381 O  O    . HOH K 7 .   ? -7.82088  -31.29748 14.12839 1.000 23.43368 ? 456 HOH A O    1 
HETATM 4382 O  O    . HOH K 7 .   ? 1.31241   0.03846   4.01287  1.000 16.06510 ? 457 HOH A O    1 
HETATM 4383 O  O    . HOH K 7 .   ? 0.03585   -28.25066 1.80946  1.000 39.34399 ? 458 HOH A O    1 
HETATM 4384 O  O    . HOH K 7 .   ? -13.47161 7.90476   28.81484 1.000 39.38061 ? 459 HOH A O    1 
HETATM 4385 O  O    . HOH K 7 .   ? -18.05969 -13.43284 31.05997 1.000 20.01672 ? 460 HOH A O    1 
HETATM 4386 O  O    . HOH K 7 .   ? -8.09344  -25.55766 3.75458  1.000 18.44843 ? 461 HOH A O    1 
HETATM 4387 O  O    . HOH K 7 .   ? -8.21339  -19.13690 -0.97342 1.000 37.80831 ? 462 HOH A O    1 
HETATM 4388 O  O    . HOH K 7 .   ? -23.89199 -0.92679  31.28118 1.000 19.55726 ? 463 HOH A O    1 
HETATM 4389 O  O    . HOH K 7 .   ? 8.77355   -17.24467 19.96449 1.000 19.27817 ? 464 HOH A O    1 
HETATM 4390 O  O    . HOH K 7 .   ? 7.37282   -3.87220  26.34850 1.000 22.45698 ? 465 HOH A O    1 
HETATM 4391 O  O    . HOH K 7 .   ? -14.96291 -10.06589 6.67157  1.000 28.71516 ? 466 HOH A O    1 
HETATM 4392 O  O    . HOH K 7 .   ? 4.31649   -15.77787 34.65948 1.000 32.37526 ? 467 HOH A O    1 
HETATM 4393 O  O    . HOH K 7 .   ? -15.91326 -16.69421 5.33920  1.000 29.04763 ? 468 HOH A O    1 
HETATM 4394 O  O    . HOH K 7 .   ? -3.46683  -14.20858 -4.77422 1.000 45.92627 ? 469 HOH A O    1 
HETATM 4395 O  O    . HOH K 7 .   ? -20.83418 -14.94437 17.73736 1.000 31.97676 ? 470 HOH A O    1 
HETATM 4396 O  O    . HOH K 7 .   ? 2.37057   -6.97228  -2.36138 1.000 22.87408 ? 471 HOH A O    1 
HETATM 4397 O  O    . HOH K 7 .   ? 11.34311  -6.25802  11.33820 1.000 38.55697 ? 472 HOH A O    1 
HETATM 4398 O  O    . HOH K 7 .   ? 9.24422   -5.25844  6.45240  1.000 29.00345 ? 473 HOH A O    1 
HETATM 4399 O  O    . HOH K 7 .   ? 8.79583   4.31907   8.16482  1.000 43.36212 ? 474 HOH A O    1 
HETATM 4400 O  O    . HOH K 7 .   ? 3.89625   -1.26139  14.98416 1.000 11.90617 ? 475 HOH A O    1 
HETATM 4401 O  O    . HOH K 7 .   ? -15.17289 -12.55581 9.77864  1.000 36.00846 ? 476 HOH A O    1 
HETATM 4402 O  O    . HOH K 7 .   ? -15.10173 -29.57128 15.18405 1.000 43.67462 ? 477 HOH A O    1 
HETATM 4403 O  O    . HOH K 7 .   ? -5.91802  -9.66572  7.52696  1.000 12.13236 ? 478 HOH A O    1 
HETATM 4404 O  O    . HOH K 7 .   ? -5.11625  4.07487   32.99208 1.000 36.14175 ? 479 HOH A O    1 
HETATM 4405 O  O    . HOH K 7 .   ? -14.06630 -20.75595 5.45692  1.000 17.29736 ? 480 HOH A O    1 
HETATM 4406 O  O    . HOH K 7 .   ? 4.41095   3.06813   9.08190  1.000 20.74961 ? 481 HOH A O    1 
HETATM 4407 O  O    . HOH K 7 .   ? 3.60714   -10.70770 -4.90683 1.000 28.04520 ? 482 HOH A O    1 
HETATM 4408 O  O    . HOH K 7 .   ? -2.94625  -6.37474  33.73390 1.000 28.68144 ? 483 HOH A O    1 
HETATM 4409 O  O    . HOH K 7 .   ? -20.24713 -12.99039 29.19947 1.000 19.98464 ? 484 HOH A O    1 
HETATM 4410 O  O    . HOH K 7 .   ? 11.14384  -17.07515 1.02601  1.000 36.26148 ? 485 HOH A O    1 
HETATM 4411 O  O    . HOH K 7 .   ? -12.36657 -6.95262  13.97677 1.000 22.55498 ? 486 HOH A O    1 
HETATM 4412 O  O    . HOH K 7 .   ? -6.06612  -27.09205 2.03099  1.000 37.82685 ? 487 HOH A O    1 
HETATM 4413 O  O    . HOH K 7 .   ? -4.90262  -5.02831  -1.23243 1.000 44.56827 ? 488 HOH A O    1 
HETATM 4414 O  O    . HOH K 7 .   ? 5.63471   -0.93568  27.15202 1.000 18.48014 ? 489 HOH A O    1 
HETATM 4415 O  O    . HOH K 7 .   ? -24.32444 -3.44646  30.22636 1.000 37.45411 ? 490 HOH A O    1 
HETATM 4416 O  O    . HOH K 7 .   ? 9.36195   -6.04014  26.29440 1.000 37.67661 ? 491 HOH A O    1 
HETATM 4417 O  O    . HOH K 7 .   ? -17.08128 -14.25217 8.31543  1.000 41.97372 ? 492 HOH A O    1 
HETATM 4418 O  O    . HOH K 7 .   ? 12.12008  -2.14123  4.52598  1.000 29.65015 ? 493 HOH A O    1 
HETATM 4419 O  O    . HOH K 7 .   ? 9.92530   -12.63407 0.13763  1.000 17.61650 ? 494 HOH A O    1 
HETATM 4420 O  O    . HOH K 7 .   ? -9.63323  -19.53484 28.73701 1.000 11.45424 ? 495 HOH A O    1 
HETATM 4421 O  O    . HOH K 7 .   ? -17.27047 15.37371  22.56808 1.000 33.31260 ? 496 HOH A O    1 
HETATM 4422 O  O    . HOH K 7 .   ? 10.20080  -13.00640 -5.44287 1.000 38.51469 ? 497 HOH A O    1 
HETATM 4423 O  O    . HOH K 7 .   ? -12.25634 -31.71624 8.34111  1.000 46.92472 ? 498 HOH A O    1 
HETATM 4424 O  O    . HOH K 7 .   ? 1.88240   -20.36395 -3.30427 1.000 52.56403 ? 499 HOH A O    1 
HETATM 4425 O  O    . HOH K 7 .   ? 3.63673   3.19457   6.34692  1.000 36.67427 ? 500 HOH A O    1 
HETATM 4426 O  O    . HOH K 7 .   ? 11.12445  -21.08668 9.82855  1.000 29.68680 ? 501 HOH A O    1 
HETATM 4427 O  O    A HOH K 7 .   ? 10.45518  -7.60879  7.57870  0.675 20.93394 ? 502 HOH A O    1 
HETATM 4428 O  O    B HOH K 7 .   ? 10.72977  -7.67301  6.41861  0.325 19.67717 ? 502 HOH A O    1 
HETATM 4429 O  O    . HOH K 7 .   ? 6.13009   2.77319   23.68345 1.000 14.32781 ? 503 HOH A O    1 
HETATM 4430 O  O    A HOH K 7 .   ? -17.15174 -19.20656 11.11244 0.572 18.77381 ? 504 HOH A O    1 
HETATM 4431 O  O    B HOH K 7 .   ? -16.59777 -18.11237 10.26793 0.428 24.89711 ? 504 HOH A O    1 
HETATM 4432 O  O    . HOH K 7 .   ? -12.16699 -10.94881 16.99746 1.000 12.52719 ? 505 HOH A O    1 
HETATM 4433 O  O    . HOH K 7 .   ? -2.28662  -19.09019 31.71409 1.000 20.55912 ? 506 HOH A O    1 
HETATM 4434 O  O    . HOH K 7 .   ? -17.36510 -26.77972 2.95126  1.000 18.41186 ? 507 HOH A O    1 
HETATM 4435 O  O    . HOH K 7 .   ? 10.84579  -15.35676 19.93086 1.000 36.42756 ? 508 HOH A O    1 
HETATM 4436 O  O    . HOH K 7 .   ? -0.18248  -18.71054 27.66325 1.000 34.21136 ? 509 HOH A O    1 
HETATM 4437 O  O    . HOH K 7 .   ? 11.42437  -7.15116  22.77320 1.000 34.67260 ? 510 HOH A O    1 
HETATM 4438 O  O    . HOH K 7 .   ? 4.79874   -4.76775  31.73507 1.000 24.66295 ? 511 HOH A O    1 
HETATM 4439 O  O    A HOH K 7 .   ? 8.13684   6.70921   17.72632 0.575 25.61195 ? 512 HOH A O    1 
HETATM 4440 O  O    B HOH K 7 .   ? 8.25475   8.22805   18.45958 0.425 16.77162 ? 512 HOH A O    1 
HETATM 4441 O  O    . HOH K 7 .   ? -21.47730 -8.48925  23.33013 1.000 36.93228 ? 513 HOH A O    1 
HETATM 4442 O  O    . HOH K 7 .   ? 6.91258   4.69990   21.90984 1.000 15.96428 ? 514 HOH A O    1 
HETATM 4443 O  O    . HOH K 7 .   ? 1.93919   -3.12722  -2.65865 1.000 22.59179 ? 515 HOH A O    1 
HETATM 4444 O  O    . HOH K 7 .   ? 6.98133   -6.08295  12.12149 1.000 15.64070 ? 516 HOH A O    1 
HETATM 4445 O  O    . HOH K 7 .   ? -5.67784  -7.78253  0.64409  1.000 21.25630 ? 517 HOH A O    1 
HETATM 4446 O  O    . HOH K 7 .   ? -5.17091  -16.66473 -1.84202 1.000 22.19153 ? 518 HOH A O    1 
HETATM 4447 O  O    . HOH K 7 .   ? 7.02502   -26.98975 11.67152 1.000 30.91110 ? 519 HOH A O    1 
HETATM 4448 O  O    A HOH K 7 .   ? 4.07353   -14.76579 37.40039 0.636 15.77706 ? 520 HOH A O    1 
HETATM 4449 O  O    B HOH K 7 .   ? 3.95906   -13.41157 36.13326 0.364 21.06892 ? 520 HOH A O    1 
HETATM 4450 O  O    . HOH K 7 .   ? -10.11792 -20.92098 34.76444 1.000 26.13303 ? 521 HOH A O    1 
HETATM 4451 O  O    A HOH K 7 .   ? -21.40413 -9.86814  14.80160 0.513 34.03859 ? 522 HOH A O    1 
HETATM 4452 O  O    B HOH K 7 .   ? -21.47998 -8.43501  15.17256 0.487 31.06535 ? 522 HOH A O    1 
HETATM 4453 O  O    . HOH K 7 .   ? -17.77308 -5.63294  40.15823 1.000 47.69731 ? 523 HOH A O    1 
HETATM 4454 O  O    . HOH K 7 .   ? 3.12505   -8.58253  10.94205 1.000 37.02713 ? 524 HOH A O    1 
HETATM 4455 O  O    . HOH K 7 .   ? -13.91614 5.76587   11.19710 1.000 41.14054 ? 525 HOH A O    1 
HETATM 4456 O  O    . HOH K 7 .   ? -12.13101 16.22140  26.08622 1.000 55.08252 ? 526 HOH A O    1 
HETATM 4457 O  O    . HOH K 7 .   ? 11.82060  -20.90684 14.49894 1.000 44.73670 ? 527 HOH A O    1 
HETATM 4458 O  O    . HOH K 7 .   ? 12.61116  -11.13355 15.13639 1.000 27.07707 ? 528 HOH A O    1 
HETATM 4459 O  O    . HOH K 7 .   ? -20.51418 2.94766   35.12529 1.000 31.89451 ? 529 HOH A O    1 
HETATM 4460 O  O    . HOH K 7 .   ? 1.10066   -15.96302 -3.94776 1.000 48.80328 ? 530 HOH A O    1 
HETATM 4461 O  O    . HOH K 7 .   ? 1.83001   -13.72816 -4.44643 1.000 46.19771 ? 531 HOH A O    1 
HETATM 4462 O  O    . HOH K 7 .   ? 13.30826  0.22775   9.07320  1.000 37.86020 ? 532 HOH A O    1 
HETATM 4463 O  O    . HOH K 7 .   ? -5.04150  5.55354   9.07474  1.000 56.51850 ? 533 HOH A O    1 
HETATM 4464 O  O    . HOH K 7 .   ? 14.37333  -0.83725  19.97348 1.000 50.87900 ? 534 HOH A O    1 
HETATM 4465 O  O    . HOH K 7 .   ? -18.10176 -17.86023 13.08396 1.000 41.77593 ? 535 HOH A O    1 
HETATM 4466 O  O    . HOH K 7 .   ? -20.23769 -1.02492  36.75257 1.000 45.98868 ? 536 HOH A O    1 
HETATM 4467 O  O    . HOH K 7 .   ? -14.66705 -21.04942 35.56992 1.000 34.04426 ? 537 HOH A O    1 
HETATM 4468 O  O    . HOH K 7 .   ? 5.80240   -24.00967 20.83191 1.000 29.98931 ? 538 HOH A O    1 
HETATM 4469 O  O    . HOH K 7 .   ? 4.54527   -3.61076  -2.50886 1.000 37.57005 ? 539 HOH A O    1 
HETATM 4470 O  O    . HOH K 7 .   ? 9.51839   -6.29212  9.52809  1.000 19.71926 ? 540 HOH A O    1 
HETATM 4471 O  O    . HOH K 7 .   ? -9.39940  -7.15231  7.40042  1.000 37.95516 ? 541 HOH A O    1 
HETATM 4472 O  O    . HOH K 7 .   ? 9.83131   -21.44894 12.77610 1.000 20.18475 ? 542 HOH A O    1 
HETATM 4473 O  O    . HOH K 7 .   ? -3.18296  3.04597   12.38141 1.000 44.88989 ? 543 HOH A O    1 
HETATM 4474 O  O    . HOH K 7 .   ? -1.26261  -15.54017 -2.31623 1.000 28.07615 ? 544 HOH A O    1 
HETATM 4475 O  O    . HOH K 7 .   ? -8.01217  -30.69426 2.72862  1.000 57.24279 ? 545 HOH A O    1 
HETATM 4476 O  O    . HOH K 7 .   ? 11.80627  -18.33331 13.70504 1.000 19.64004 ? 546 HOH A O    1 
HETATM 4477 O  O    . HOH K 7 .   ? -18.98547 -10.42646 34.25892 1.000 45.37709 ? 547 HOH A O    1 
HETATM 4478 O  O    . HOH K 7 .   ? -1.55618  -3.09926  5.15543  1.000 30.15373 ? 548 HOH A O    1 
HETATM 4479 O  O    . HOH K 7 .   ? -14.86844 -14.75449 12.47775 1.000 38.41260 ? 549 HOH A O    1 
HETATM 4480 O  O    . HOH K 7 .   ? 12.72752  -20.28320 4.31309  1.000 52.79556 ? 550 HOH A O    1 
HETATM 4481 O  O    . HOH K 7 .   ? -14.12346 -22.82596 23.59594 1.000 42.69167 ? 551 HOH A O    1 
HETATM 4482 O  O    . HOH K 7 .   ? -1.65317  -30.87856 11.40237 1.000 36.97121 ? 552 HOH A O    1 
HETATM 4483 O  O    . HOH K 7 .   ? -21.31462 -11.20350 19.75475 1.000 31.41118 ? 553 HOH A O    1 
HETATM 4484 O  O    . HOH K 7 .   ? -21.80262 -11.56237 22.93712 1.000 30.49862 ? 554 HOH A O    1 
HETATM 4485 O  O    . HOH K 7 .   ? -25.49255 -1.65783  27.82852 1.000 47.02368 ? 555 HOH A O    1 
HETATM 4486 O  O    . HOH K 7 .   ? 4.97904   -30.77363 16.20358 1.000 35.89051 ? 556 HOH A O    1 
HETATM 4487 O  O    . HOH K 7 .   ? -4.32518  -0.12413  8.51048  1.000 49.79470 ? 557 HOH A O    1 
HETATM 4488 O  O    . HOH K 7 .   ? -21.17002 -9.09408  26.90756 1.000 51.67352 ? 558 HOH A O    1 
HETATM 4489 O  O    . HOH K 7 .   ? 6.68210   -13.37762 33.48221 1.000 47.49443 ? 559 HOH A O    1 
HETATM 4490 O  O    . HOH K 7 .   ? -4.22309  -1.78105  1.40418  1.000 42.26581 ? 560 HOH A O    1 
HETATM 4491 O  O    . HOH K 7 .   ? 13.91842  -12.47818 8.82287  1.000 36.89176 ? 561 HOH A O    1 
HETATM 4492 O  O    . HOH K 7 .   ? 2.91511   -18.06678 24.69056 1.000 25.97181 ? 562 HOH A O    1 
HETATM 4493 O  O    . HOH K 7 .   ? -22.02131 -7.85345  19.59460 1.000 48.96370 ? 563 HOH A O    1 
HETATM 4494 O  O    . HOH K 7 .   ? 3.24641   -33.44774 23.27550 1.000 32.13356 ? 564 HOH A O    1 
HETATM 4495 O  O    . HOH K 7 .   ? -6.01762  5.20819   25.66992 1.000 24.38836 ? 565 HOH A O    1 
HETATM 4496 O  O    . HOH K 7 .   ? -10.09394 -18.76845 35.95410 1.000 28.72015 ? 566 HOH A O    1 
HETATM 4497 O  O    . HOH K 7 .   ? 7.07825   -28.52885 14.28287 1.000 55.44925 ? 567 HOH A O    1 
HETATM 4498 O  O    . HOH K 7 .   ? 9.21303   -7.69310  4.60662  1.000 20.28292 ? 568 HOH A O    1 
HETATM 4499 O  O    . HOH K 7 .   ? 4.86003   -31.68804 5.02484  1.000 41.91048 ? 569 HOH A O    1 
HETATM 4500 O  O    . HOH K 7 .   ? -17.42089 -11.71915 8.65639  1.000 50.46932 ? 570 HOH A O    1 
HETATM 4501 O  O    . HOH K 7 .   ? 3.10159   -22.22406 -2.49624 1.000 37.65741 ? 571 HOH A O    1 
HETATM 4502 O  O    . HOH K 7 .   ? -3.00603  -12.35849 33.80545 1.000 60.00765 ? 572 HOH A O    1 
HETATM 4503 O  O    A HOH K 7 .   ? -14.47774 -23.39670 31.66464 0.594 33.40925 ? 573 HOH A O    1 
HETATM 4504 O  O    . HOH K 7 .   ? 10.66016  -14.64515 24.55073 1.000 45.73840 ? 574 HOH A O    1 
HETATM 4505 O  O    . HOH K 7 .   ? -19.01220 7.20491   32.65526 1.000 46.41653 ? 575 HOH A O    1 
HETATM 4506 O  O    . HOH K 7 .   ? -6.61639  -2.82233  2.36245  1.000 50.07097 ? 576 HOH A O    1 
HETATM 4507 O  O    . HOH K 7 .   ? 9.66001   -9.64350  25.44039 1.000 42.63052 ? 577 HOH A O    1 
HETATM 4508 O  O    . HOH K 7 .   ? -15.26208 7.55893   31.31679 1.000 28.62299 ? 578 HOH A O    1 
HETATM 4509 O  O    . HOH K 7 .   ? 13.13551  -10.93321 11.83279 1.000 43.57604 ? 579 HOH A O    1 
HETATM 4510 O  O    . HOH K 7 .   ? 7.72967   -17.92438 22.44057 1.000 33.64621 ? 580 HOH A O    1 
HETATM 4511 O  O    . HOH K 7 .   ? 11.81510  0.77970   19.55693 1.000 38.73381 ? 581 HOH A O    1 
HETATM 4512 O  O    . HOH K 7 .   ? 6.79697   -28.88279 9.33822  1.000 46.28251 ? 582 HOH A O    1 
HETATM 4513 O  O    . HOH K 7 .   ? -0.48991  -37.57147 13.20163 1.000 57.75820 ? 583 HOH A O    1 
HETATM 4514 O  O    . HOH K 7 .   ? -14.28989 16.25001  23.28910 1.000 29.56102 ? 584 HOH A O    1 
HETATM 4515 O  O    . HOH K 7 .   ? -17.42044 -27.26409 13.13476 1.000 45.41478 ? 585 HOH A O    1 
HETATM 4516 O  O    . HOH K 7 .   ? -5.64184  -8.40239  33.51668 1.000 36.74092 ? 586 HOH A O    1 
HETATM 4517 O  O    . HOH K 7 .   ? -0.96761  -21.78002 27.62147 1.000 23.20186 ? 587 HOH A O    1 
HETATM 4518 O  O    . HOH K 7 .   ? -24.09086 -0.31449  19.55446 1.000 49.75879 ? 588 HOH A O    1 
HETATM 4519 O  O    . HOH K 7 .   ? -19.02416 -19.78993 23.15565 1.000 43.72424 ? 589 HOH A O    1 
HETATM 4520 O  O    . HOH K 7 .   ? -23.48094 0.84129   34.90581 1.000 49.18087 ? 590 HOH A O    1 
HETATM 4521 O  O    . HOH K 7 .   ? -8.90743  -29.27449 4.16835  1.000 45.32294 ? 591 HOH A O    1 
HETATM 4522 O  O    . HOH K 7 .   ? 11.52091  2.56570   14.86103 1.000 42.66189 ? 592 HOH A O    1 
HETATM 4523 O  O    . HOH K 7 .   ? -3.41401  -31.58660 22.74942 1.000 48.20897 ? 593 HOH A O    1 
HETATM 4524 O  O    . HOH K 7 .   ? -7.92145  -21.28774 -2.62934 1.000 49.28458 ? 594 HOH A O    1 
HETATM 4525 O  O    . HOH K 7 .   ? 14.20021  -14.33283 16.12109 1.000 58.21582 ? 595 HOH A O    1 
HETATM 4526 O  O    . HOH K 7 .   ? -19.18762 17.23350  20.58670 1.000 54.16396 ? 596 HOH A O    1 
HETATM 4527 O  O    . HOH K 7 .   ? -16.67368 -16.10921 11.01695 1.000 51.37573 ? 597 HOH A O    1 
HETATM 4528 O  O    . HOH K 7 .   ? -21.40643 -15.26724 14.88551 1.000 49.05941 ? 598 HOH A O    1 
HETATM 4529 O  O    . HOH K 7 .   ? -7.34989  10.94438  23.64887 1.000 44.96048 ? 599 HOH A O    1 
HETATM 4530 O  O    . HOH K 7 .   ? 15.88957  -16.66372 5.83004  1.000 46.18960 ? 600 HOH A O    1 
HETATM 4531 O  O    . HOH K 7 .   ? -1.83365  -0.83504  4.47467  1.000 61.82943 ? 601 HOH A O    1 
HETATM 4532 O  O    . HOH K 7 .   ? -22.45251 0.12381   21.84340 1.000 40.53257 ? 602 HOH A O    1 
HETATM 4533 O  O    . HOH K 7 .   ? -3.78016  -20.92906 -2.52878 1.000 50.18306 ? 603 HOH A O    1 
HETATM 4534 O  O    A HOH K 7 .   ? -6.90041  -6.86854  8.15091  0.578 24.51690 ? 604 HOH A O    1 
HETATM 4535 O  O    B HOH K 7 .   ? -6.35451  -6.95217  7.02620  0.422 27.46113 ? 604 HOH A O    1 
HETATM 4536 O  O    . HOH K 7 .   ? 2.61368   -35.57274 15.19366 1.000 51.45047 ? 605 HOH A O    1 
HETATM 4537 O  O    . HOH K 7 .   ? 13.42593  0.38119   13.88755 1.000 50.77650 ? 606 HOH A O    1 
HETATM 4538 O  O    . HOH K 7 .   ? -19.47221 -21.72958 8.98103  1.000 53.32806 ? 607 HOH A O    1 
HETATM 4539 O  O    . HOH K 7 .   ? -10.02513 3.74176   34.20581 1.000 51.69077 ? 608 HOH A O    1 
HETATM 4540 O  O    . HOH K 7 .   ? -0.25981  3.72292   11.77838 1.000 51.19195 ? 609 HOH A O    1 
HETATM 4541 O  O    . HOH K 7 .   ? -0.69480  2.60470   8.51841  1.000 53.22297 ? 610 HOH A O    1 
HETATM 4542 O  O    . HOH K 7 .   ? -2.24409  -21.92029 -1.56370 1.000 42.25756 ? 611 HOH A O    1 
HETATM 4543 O  O    . HOH K 7 .   ? -21.68418 -17.77163 19.27250 1.000 50.24613 ? 612 HOH A O    1 
HETATM 4544 O  O    . HOH K 7 .   ? 13.65832  -5.01770  29.68787 1.000 48.33471 ? 613 HOH A O    1 
HETATM 4545 O  O    . HOH K 7 .   ? 0.02276   5.79059   12.68035 1.000 59.05653 ? 614 HOH A O    1 
HETATM 4546 O  O    . HOH K 7 .   ? -9.46314  5.02794   32.10895 1.000 29.46817 ? 615 HOH A O    1 
HETATM 4547 O  O    . HOH K 7 .   ? -21.84956 -5.99982  24.04580 1.000 41.97905 ? 616 HOH A O    1 
HETATM 4548 O  O    . HOH K 7 .   ? -6.59221  8.95822   21.58990 1.000 27.55928 ? 617 HOH A O    1 
HETATM 4549 O  O    . HOH K 7 .   ? 13.41690  -7.38251  20.58150 1.000 44.38435 ? 618 HOH A O    1 
HETATM 4550 O  O    . HOH K 7 .   ? -5.93946  -19.63622 -1.15120 1.000 39.12327 ? 619 HOH A O    1 
HETATM 4551 O  O    . HOH K 7 .   ? -13.76189 -18.67318 37.29184 1.000 60.75783 ? 620 HOH A O    1 
HETATM 4552 O  O    . HOH K 7 .   ? 6.36999   -26.65779 22.25380 1.000 50.98793 ? 621 HOH A O    1 
HETATM 4553 O  O    . HOH K 7 .   ? -22.00601 -7.83269  29.98884 1.000 35.78253 ? 622 HOH A O    1 
HETATM 4554 O  O    . HOH K 7 .   ? 5.90413   -19.64194 22.77610 1.000 35.74936 ? 623 HOH A O    1 
HETATM 4555 O  O    . HOH K 7 .   ? -3.07024  -33.72009 22.70617 1.000 41.06922 ? 624 HOH A O    1 
HETATM 4556 O  O    . HOH K 7 .   ? -11.14792 -23.83522 0.11908  1.000 35.09034 ? 625 HOH A O    1 
HETATM 4557 O  O    . HOH K 7 .   ? -22.86987 -14.47020 25.42378 1.000 52.23228 ? 626 HOH A O    1 
HETATM 4558 O  O    . HOH K 7 .   ? -16.21616 -21.64459 25.10038 1.000 51.76609 ? 627 HOH A O    1 
HETATM 4559 O  O    . HOH K 7 .   ? -20.09492 -26.75284 3.15418  1.000 32.31591 ? 628 HOH A O    1 
HETATM 4560 O  O    . HOH K 7 .   ? 4.10985   -7.36517  -4.44763 1.000 40.19846 ? 629 HOH A O    1 
HETATM 4561 O  O    . HOH K 7 .   ? 11.20250  -9.16651  3.61836  1.000 25.61750 ? 630 HOH A O    1 
HETATM 4562 O  O    . HOH K 7 .   ? 11.53364  3.46071   20.53283 1.000 57.41688 ? 631 HOH A O    1 
HETATM 4563 O  O    . HOH K 7 .   ? -16.49015 -19.42869 4.85635  1.000 21.87685 ? 632 HOH A O    1 
HETATM 4564 O  O    . HOH K 7 .   ? 14.00976  -16.75865 14.76065 1.000 42.07045 ? 633 HOH A O    1 
HETATM 4565 O  O    . HOH K 7 .   ? -3.02968  -12.74977 40.38980 1.000 38.85995 ? 634 HOH A O    1 
HETATM 4566 O  O    . HOH K 7 .   ? 3.88597   7.36055   14.85625 1.000 40.59068 ? 635 HOH A O    1 
HETATM 4567 O  O    . HOH K 7 .   ? -4.84652  -35.90898 13.67737 1.000 41.94899 ? 636 HOH A O    1 
HETATM 4568 O  O    . HOH K 7 .   ? -6.99035  6.20087   32.84441 1.000 19.21743 ? 637 HOH A O    1 
HETATM 4569 O  O    . HOH K 7 .   ? -10.48800 -24.81548 -4.86158 1.000 38.67188 ? 638 HOH A O    1 
HETATM 4570 O  O    . HOH K 7 .   ? 12.05730  -20.29726 7.68900  1.000 48.27571 ? 639 HOH A O    1 
HETATM 4571 O  O    . HOH K 7 .   ? -12.99275 18.21623  21.77603 1.000 43.34520 ? 640 HOH A O    1 
HETATM 4572 O  O    . HOH K 7 .   ? -3.17867  -18.22355 33.92495 1.000 22.97065 ? 641 HOH A O    1 
HETATM 4573 O  O    . HOH K 7 .   ? -6.46299  -26.92008 28.56042 1.000 32.24510 ? 642 HOH A O    1 
HETATM 4574 O  O    . HOH K 7 .   ? 13.05657  -7.76942  7.03513  1.000 48.01655 ? 643 HOH A O    1 
HETATM 4575 O  O    . HOH K 7 .   ? -22.21932 -11.46409 30.32534 1.000 37.76768 ? 644 HOH A O    1 
HETATM 4576 O  O    . HOH K 7 .   ? -4.91655  -30.25433 24.62480 1.000 49.35208 ? 645 HOH A O    1 
HETATM 4577 O  O    . HOH K 7 .   ? -23.56578 -5.54762  26.34219 1.000 44.28388 ? 646 HOH A O    1 
HETATM 4578 O  O    . HOH K 7 .   ? 5.78973   -22.24074 22.81747 1.000 33.77484 ? 647 HOH A O    1 
HETATM 4579 O  O    . HOH K 7 .   ? -23.69572 6.70957   32.69605 1.000 21.09545 ? 648 HOH A O    1 
HETATM 4580 O  O    . HOH K 7 .   ? -2.59894  1.86343   9.60857  1.000 55.16815 ? 649 HOH A O    1 
HETATM 4581 O  O    . HOH K 7 .   ? -10.68954 18.42318  24.66768 1.000 38.86973 ? 650 HOH A O    1 
HETATM 4582 O  O    . HOH K 7 .   ? 13.51811  -9.65573  16.59169 1.000 51.21555 ? 651 HOH A O    1 
HETATM 4583 O  O    . HOH K 7 .   ? 12.14162  -14.14761 -0.17748 1.000 30.00905 ? 652 HOH A O    1 
HETATM 4584 O  O    . HOH K 7 .   ? -7.70373  -15.69823 -1.44452 1.000 30.14176 ? 653 HOH A O    1 
HETATM 4585 O  O    . HOH K 7 .   ? -4.98593  -26.15427 30.54989 1.000 22.73504 ? 654 HOH A O    1 
HETATM 4586 O  O    . HOH K 7 .   ? -12.58356 -27.00025 0.19667  1.000 42.37019 ? 655 HOH A O    1 
HETATM 4587 O  O    . HOH K 7 .   ? 12.01095  -4.82245  5.42874  1.000 32.30902 ? 656 HOH A O    1 
HETATM 4588 O  O    A HOH K 7 .   ? 6.44211   4.82702   9.16268  0.524 31.83623 ? 657 HOH A O    1 
HETATM 4589 O  O    B HOH K 7 .   ? 5.68551   5.48637   10.33603 0.476 39.78252 ? 657 HOH A O    1 
HETATM 4590 O  O    . HOH K 7 .   ? -23.83707 -12.87000 22.98813 1.000 49.31235 ? 658 HOH A O    1 
HETATM 4591 O  O    . HOH K 7 .   ? -21.43225 -24.34383 2.67700  1.000 48.11151 ? 659 HOH A O    1 
HETATM 4592 O  O    . HOH K 7 .   ? 13.85762  -9.44749  -0.10249 1.000 19.15649 ? 660 HOH A O    1 
HETATM 4593 O  O    . HOH K 7 .   ? -9.20390  -28.66975 2.10291  1.000 54.95488 ? 661 HOH A O    1 
HETATM 4594 O  O    . HOH K 7 .   ? 12.85006  -6.95586  3.80545  1.000 44.40238 ? 662 HOH A O    1 
HETATM 4595 O  O    . HOH K 7 .   ? -5.56204  -29.42018 26.69392 1.000 59.37193 ? 663 HOH A O    1 
HETATM 4596 O  O    . HOH K 7 .   ? 2.58289   -11.47372 -9.61638 1.000 38.45851 ? 664 HOH A O    1 
HETATM 4597 O  O    . HOH K 7 .   ? 14.42160  -12.15221 0.83684  1.000 32.65766 ? 665 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N  N   . ALA A 5   ? 0.79478 0.53930 0.58617 -0.00063 0.02564  -0.01548 28  ALA A N   
2    C  CA  . ALA A 5   ? 0.77688 0.52795 0.58352 0.01009  0.03033  -0.01355 28  ALA A CA  
3    C  C   . ALA A 5   ? 0.71678 0.51802 0.57579 0.02870  0.04063  -0.01209 28  ALA A C   
4    O  O   . ALA A 5   ? 0.70480 0.49257 0.57870 0.02391  0.04497  0.00358  28  ALA A O   
5    C  CB  . ALA A 5   ? 0.79368 0.53563 0.58551 0.00550  0.02619  -0.01220 28  ALA A CB  
11   N  N   . ASP A 6   ? 0.64847 0.51733 0.55902 0.07225  0.05423  -0.02758 29  ASP A N   
12   C  CA  . ASP A 6   ? 0.56298 0.51956 0.53453 0.11238  0.06961  -0.04442 29  ASP A CA  
13   C  C   . ASP A 6   ? 0.45264 0.41092 0.50023 0.11738  0.08202  -0.06223 29  ASP A C   
14   O  O   . ASP A 6   ? 0.43161 0.37409 0.49500 0.12332  0.10449  -0.07948 29  ASP A O   
15   C  CB  . ASP A 6   ? 0.60227 0.63854 0.54632 0.12450  0.06895  -0.03521 29  ASP A CB  
16   C  CG  . ASP A 6   ? 0.64342 0.73826 0.56068 0.12741  0.06527  -0.01893 29  ASP A CG  
17   O  OD1 . ASP A 6   ? 0.65484 0.77376 0.56449 0.12189  0.06661  -0.01438 29  ASP A OD1 
18   O  OD2 . ASP A 6   ? 0.65613 0.76901 0.56693 0.13064  0.06159  -0.01364 29  ASP A OD2 
23   N  N   A VAL A 7   ? 0.41147 0.38133 0.48611 0.10401  0.07909  -0.05955 30  VAL A N   
24   N  N   B VAL A 7   ? 0.42121 0.38302 0.48576 0.11020  0.07574  -0.05782 30  VAL A N   
25   C  CA  A VAL A 7   ? 0.37031 0.36060 0.46996 0.09857  0.07918  -0.06060 30  VAL A CA  
26   C  CA  B VAL A 7   ? 0.38880 0.36688 0.46921 0.11042  0.07275  -0.05808 30  VAL A CA  
27   C  C   A VAL A 7   ? 0.35631 0.35906 0.45644 0.10356  0.07476  -0.06807 30  VAL A C   
28   C  C   B VAL A 7   ? 0.36187 0.35294 0.45454 0.11270  0.07360  -0.07086 30  VAL A C   
29   O  O   A VAL A 7   ? 0.34674 0.32375 0.44991 0.09918  0.08492  -0.08159 30  VAL A O   
30   O  O   B VAL A 7   ? 0.34814 0.29608 0.44533 0.11044  0.08759  -0.09227 30  VAL A O   
31   C  CB  A VAL A 7   ? 0.35277 0.34996 0.46911 0.09138  0.07824  -0.05094 30  VAL A CB  
32   C  CB  B VAL A 7   ? 0.39467 0.37572 0.46950 0.10868  0.06189  -0.04150 30  VAL A CB  
33   C  CG1 A VAL A 7   ? 0.33646 0.33925 0.46905 0.10197  0.08439  -0.05064 30  VAL A CG1 
34   C  CG1 B VAL A 7   ? 0.38182 0.37100 0.46830 0.14581  0.05905  -0.03204 30  VAL A CG1 
35   C  CG2 A VAL A 7   ? 0.34159 0.34735 0.46862 0.09687  0.07476  -0.04515 30  VAL A CG2 
36   C  CG2 B VAL A 7   ? 0.40034 0.38830 0.47159 0.09215  0.05907  -0.03936 30  VAL A CG2 
55   N  N   . GLN A 8   ? 0.36515 0.38024 0.45093 0.10914  0.05837  -0.06158 31  GLN A N   
56   C  CA  . GLN A 8   ? 0.37600 0.42672 0.44216 0.12649  0.05238  -0.06139 31  GLN A CA  
57   C  C   . GLN A 8   ? 0.34131 0.46143 0.42851 0.13436  0.03459  -0.05735 31  GLN A C   
58   O  O   . GLN A 8   ? 0.29101 0.45596 0.42988 0.11884  0.00787  -0.04081 31  GLN A O   
59   C  CB  . GLN A 8   ? 0.39919 0.41913 0.44509 0.16515  0.07365  -0.08235 31  GLN A CB  
60   C  CG  . GLN A 8   ? 0.45168 0.43249 0.44753 0.15909  0.08173  -0.09145 31  GLN A CG  
61   C  CD  . GLN A 8   ? 0.49019 0.43952 0.45272 0.16183  0.08789  -0.10418 31  GLN A CD  
62   O  OE1 . GLN A 8   ? 0.51764 0.44860 0.45653 0.17178  0.07800  -0.08282 31  GLN A OE1 
63   N  NE2 . GLN A 8   ? 0.47163 0.44812 0.45282 0.16078  0.10479  -0.11742 31  GLN A NE2 
73   N  N   . GLN A 9   ? 0.35109 0.48075 0.41248 0.14844  0.05160  -0.06600 32  GLN A N   
74   C  CA  . GLN A 9   ? 0.37545 0.50548 0.39605 0.14100  0.07900  -0.08926 32  GLN A CA  
75   C  C   . GLN A 9   ? 0.33030 0.43986 0.36030 0.07250  0.09656  -0.10742 32  GLN A C   
76   O  O   . GLN A 9   ? 0.29427 0.39766 0.35465 0.03660  0.09774  -0.10965 32  GLN A O   
77   C  CB  . GLN A 9   ? 0.46497 0.59703 0.41459 0.17466  0.08968  -0.08728 32  GLN A CB  
78   C  CG  . GLN A 9   ? 0.57363 0.70120 0.43381 0.18156  0.07685  -0.07946 32  GLN A CG  
79   C  CD  . GLN A 9   ? 0.64076 0.78330 0.44916 0.20215  0.06770  -0.06607 32  GLN A CD  
80   O  OE1 . GLN A 9   ? 0.66939 0.81165 0.45650 0.20540  0.05825  -0.05510 32  GLN A OE1 
81   N  NE2 . GLN A 9   ? 0.66125 0.81176 0.45419 0.19992  0.06846  -0.06537 32  GLN A NE2 
90   N  N   . LYS A 10  ? 0.30326 0.38286 0.32407 0.05676  0.11557  -0.12837 33  LYS A N   
91   C  CA  . LYS A 10  ? 0.29266 0.34764 0.29339 0.02483  0.10648  -0.13020 33  LYS A CA  
92   C  C   . LYS A 10  ? 0.23109 0.31677 0.24317 0.00492  0.08256  -0.12434 33  LYS A C   
93   O  O   . LYS A 10  ? 0.24122 0.31217 0.23227 -0.03108 0.06805  -0.12820 33  LYS A O   
94   C  CB  . LYS A 10  ? 0.32808 0.34689 0.30457 0.00357  0.11518  -0.14306 33  LYS A CB  
95   C  CG  . LYS A 10  ? 0.39798 0.38133 0.31653 -0.02696 0.11676  -0.14451 33  LYS A CG  
96   C  CD  . LYS A 10  ? 0.44972 0.45454 0.32896 -0.03507 0.11048  -0.13647 33  LYS A CD  
97   C  CE  . LYS A 10  ? 0.50222 0.54928 0.34915 -0.05389 0.10305  -0.11579 33  LYS A CE  
98   N  NZ  . LYS A 10  ? 0.53646 0.60101 0.36314 -0.05767 0.09517  -0.08927 33  LYS A NZ  
112  N  N   . LEU A 11  ? 0.20945 0.30223 0.20558 0.01335  0.04984  -0.09051 34  LEU A N   
113  C  CA  . LEU A 11  ? 0.18627 0.29934 0.17439 0.02146  0.04490  -0.06539 34  LEU A CA  
114  C  C   . LEU A 11  ? 0.20377 0.33826 0.17552 0.00748  0.04889  -0.06071 34  LEU A C   
115  O  O   . LEU A 11  ? 0.20636 0.28466 0.16556 0.01510  0.04399  -0.04416 34  LEU A O   
116  C  CB  . LEU A 11  ? 0.21177 0.29001 0.16826 0.00718  0.03104  -0.05159 34  LEU A CB  
117  C  CG  . LEU A 11  ? 0.19489 0.27381 0.16882 0.00747  0.01986  -0.05152 34  LEU A CG  
118  C  CD1 . LEU A 11  ? 0.18824 0.26776 0.16893 -0.01665 -0.00760 -0.04681 34  LEU A CD1 
119  C  CD2 . LEU A 11  ? 0.16844 0.24480 0.16963 0.01185  0.02854  -0.06038 34  LEU A CD2 
131  N  N   . ALA A 12  ? 0.20797 0.36883 0.18710 -0.00561 0.06642  -0.05948 35  ALA A N   
132  C  CA  . ALA A 12  ? 0.19890 0.37994 0.21021 0.01500  0.07206  -0.05042 35  ALA A CA  
133  C  C   . ALA A 12  ? 0.20561 0.38906 0.21496 0.01376  0.07207  -0.05558 35  ALA A C   
134  O  O   . ALA A 12  ? 0.21522 0.36948 0.21970 -0.01703 0.07910  -0.07194 35  ALA A O   
135  C  CB  . ALA A 12  ? 0.20725 0.41418 0.22610 0.03626  0.05777  -0.03473 35  ALA A CB  
141  N  N   . GLU A 13  ? 0.22045 0.39100 0.20765 0.00440  0.08188  -0.06772 36  GLU A N   
142  C  CA  . GLU A 13  ? 0.23239 0.39966 0.20946 -0.01309 0.09688  -0.08716 36  GLU A CA  
143  C  C   . GLU A 13  ? 0.20797 0.35252 0.19470 -0.02009 0.08896  -0.08501 36  GLU A C   
144  O  O   . GLU A 13  ? 0.23668 0.34882 0.18952 -0.04649 0.09729  -0.08401 36  GLU A O   
145  C  CB  . GLU A 13  ? 0.31995 0.48624 0.22776 -0.03614 0.10025  -0.10963 36  GLU A CB  
146  C  CG  . GLU A 13  ? 0.43091 0.60114 0.25152 -0.06373 0.09276  -0.10051 36  GLU A CG  
147  C  CD  . GLU A 13  ? 0.52908 0.70479 0.27156 -0.08321 0.09169  -0.09990 36  GLU A CD  
148  O  OE1 . GLU A 13  ? 0.53784 0.72301 0.27663 -0.09690 0.09264  -0.12048 36  GLU A OE1 
149  O  OE2 . GLU A 13  ? 0.56876 0.73917 0.28404 -0.09373 0.09979  -0.07615 36  GLU A OE2 
156  N  N   . LEU A 14  ? 0.19611 0.32616 0.18360 -0.01618 0.06257  -0.07748 37  LEU A N   
157  C  CA  . LEU A 14  ? 0.20088 0.28061 0.17447 -0.00490 0.05370  -0.07892 37  LEU A CA  
158  C  C   . LEU A 14  ? 0.20152 0.26538 0.16304 -0.01796 0.04812  -0.06263 37  LEU A C   
159  O  O   . LEU A 14  ? 0.20660 0.27082 0.14794 -0.01617 0.06015  -0.03949 37  LEU A O   
160  C  CB  . LEU A 14  ? 0.18359 0.26328 0.17885 -0.01817 0.06422  -0.06382 37  LEU A CB  
161  C  CG  . LEU A 14  ? 0.19705 0.23479 0.17997 -0.03116 0.06639  -0.03963 37  LEU A CG  
162  C  CD1 . LEU A 14  ? 0.20895 0.25453 0.19205 -0.02200 0.05830  -0.00168 37  LEU A CD1 
163  C  CD2 . LEU A 14  ? 0.19452 0.22709 0.17714 -0.04223 0.08145  -0.05150 37  LEU A CD2 
175  N  N   . GLU A 15  ? 0.20333 0.25181 0.15763 -0.03050 0.05678  -0.03738 38  GLU A N   
176  C  CA  . GLU A 15  ? 0.19785 0.27267 0.16134 -0.02676 0.06199  -0.02340 38  GLU A CA  
177  C  C   . GLU A 15  ? 0.21016 0.31708 0.16575 -0.04285 0.05864  -0.03328 38  GLU A C   
178  O  O   . GLU A 15  ? 0.22252 0.28514 0.16636 -0.05317 0.03723  -0.03042 38  GLU A O   
179  C  CB  . GLU A 15  ? 0.20166 0.24535 0.15721 -0.01855 0.05434  -0.01620 38  GLU A CB  
180  C  CG  . GLU A 15  ? 0.20272 0.22337 0.15029 -0.02047 0.04589  0.00742  38  GLU A CG  
181  C  CD  . GLU A 15  ? 0.19815 0.20880 0.15099 -0.01038 0.05545  -0.00103 38  GLU A CD  
182  O  OE1 . GLU A 15  ? 0.19435 0.25012 0.15495 0.00450  0.06307  -0.01843 38  GLU A OE1 
183  O  OE2 . GLU A 15  ? 0.19303 0.20576 0.14421 -0.00084 0.06992  -0.01407 38  GLU A OE2 
190  N  N   . ARG A 16  ? 0.20782 0.37379 0.18822 -0.05313 0.08330  -0.04317 39  ARG A N   
191  C  CA  . ARG A 16  ? 0.25443 0.37923 0.20971 -0.05485 0.10492  -0.06780 39  ARG A CA  
192  C  C   . ARG A 16  ? 0.25378 0.37649 0.19859 -0.06179 0.10124  -0.05642 39  ARG A C   
193  O  O   . ARG A 16  ? 0.25437 0.33287 0.20474 -0.08402 0.08959  -0.04438 39  ARG A O   
194  C  CB  . ARG A 16  ? 0.34834 0.44371 0.23763 -0.01216 0.12874  -0.08670 39  ARG A CB  
195  C  CG  . ARG A 16  ? 0.47569 0.55737 0.27696 -0.00007 0.11091  -0.08443 39  ARG A CG  
196  C  CD  . ARG A 16  ? 0.55472 0.62884 0.30160 0.02409  0.10104  -0.08081 39  ARG A CD  
197  N  NE  . ARG A 16  ? 0.61606 0.68000 0.31787 0.03199  0.09530  -0.07600 39  ARG A NE  
198  C  CZ  . ARG A 16  ? 0.64557 0.70651 0.33167 0.05498  0.09976  -0.07628 39  ARG A CZ  
199  N  NH1 . ARG A 16  ? 0.64852 0.72146 0.34022 0.06400  0.10331  -0.09124 39  ARG A NH1 
200  N  NH2 . ARG A 16  ? 0.66512 0.71848 0.33968 0.05316  0.10045  -0.05899 39  ARG A NH2 
214  N  N   A GLN A 17  ? 0.24413 0.37833 0.18443 -0.06191 0.09553  -0.07470 40  GLN A N   
215  N  N   B GLN A 17  ? 0.26471 0.37060 0.18905 -0.07035 0.09170  -0.05981 40  GLN A N   
216  C  CA  A GLN A 17  ? 0.25553 0.40728 0.17421 -0.07212 0.08399  -0.07161 40  GLN A CA  
217  C  CA  B GLN A 17  ? 0.29607 0.38958 0.18475 -0.08604 0.07251  -0.04475 40  GLN A CA  
218  C  C   A GLN A 17  ? 0.23944 0.36857 0.16025 -0.08972 0.06249  -0.05723 40  GLN A C   
219  C  C   B GLN A 17  ? 0.26279 0.35683 0.16554 -0.09799 0.06064  -0.04065 40  GLN A C   
220  O  O   A GLN A 17  ? 0.23559 0.36022 0.15224 -0.09065 0.07036  -0.06842 40  GLN A O   
221  O  O   B GLN A 17  ? 0.25983 0.34489 0.15897 -0.10831 0.07497  -0.04319 40  GLN A O   
222  C  CB  A GLN A 17  ? 0.29505 0.46175 0.18514 -0.10230 0.07490  -0.07545 40  GLN A CB  
223  C  CB  B GLN A 17  ? 0.36439 0.42697 0.20395 -0.12735 0.05471  -0.02990 40  GLN A CB  
224  C  CG  A GLN A 17  ? 0.33361 0.52485 0.19628 -0.10962 0.05709  -0.07553 40  GLN A CG  
225  C  CG  B GLN A 17  ? 0.42227 0.47530 0.21938 -0.14845 0.03141  -0.01052 40  GLN A CG  
226  C  CD  A GLN A 17  ? 0.35595 0.59359 0.21433 -0.11092 0.04665  -0.06383 40  GLN A CD  
227  C  CD  B GLN A 17  ? 0.49222 0.52539 0.23945 -0.15643 0.01534  0.00994  40  GLN A CD  
228  O  OE1 A GLN A 17  ? 0.38358 0.62406 0.21902 -0.12129 0.02443  -0.05735 40  GLN A OE1 
229  O  OE1 B GLN A 17  ? 0.52982 0.55280 0.25318 -0.15559 0.00032  0.02120  40  GLN A OE1 
230  N  NE2 A GLN A 17  ? 0.38882 0.61483 0.22593 -0.12413 0.03873  -0.06360 40  GLN A NE2 
231  N  NE2 B GLN A 17  ? 0.51485 0.54586 0.24474 -0.15727 0.02020  0.00831  40  GLN A NE2 
248  N  N   . SER A 18  ? 0.20413 0.33487 0.14676 -0.06912 0.05530  -0.04744 41  SER A N   
249  C  CA  . SER A 18  ? 0.18276 0.30916 0.13520 -0.05298 0.05320  -0.03349 41  SER A CA  
250  C  C   . SER A 18  ? 0.17708 0.32283 0.12777 -0.05485 0.02251  -0.03292 41  SER A C   
251  O  O   . SER A 18  ? 0.20679 0.28846 0.14501 -0.05445 0.00911  -0.02076 41  SER A O   
252  C  CB  . SER A 18  ? 0.18392 0.30410 0.13873 -0.06453 0.05354  -0.03486 41  SER A CB  
253  O  OG  . SER A 18  ? 0.22292 0.27471 0.14510 -0.02861 0.07384  -0.01964 41  SER A OG  
260  N  N   . GLY A 19  ? 0.16279 0.34073 0.11213 -0.03580 0.04198  -0.02782 42  GLY A N   
261  C  CA  . GLY A 19  ? 0.17567 0.30942 0.09840 -0.05200 0.02304  -0.01465 42  GLY A CA  
262  C  C   . GLY A 19  ? 0.19912 0.26659 0.11265 -0.05401 0.01897  0.01613  42  GLY A C   
263  O  O   . GLY A 19  ? 0.23446 0.26976 0.12851 -0.06156 0.02180  0.01597  42  GLY A O   
267  N  N   . GLY A 20  ? 0.17726 0.20673 0.09757 -0.02824 0.03804  0.01755  43  GLY A N   
268  C  CA  . GLY A 20  ? 0.19633 0.19325 0.09492 -0.01072 0.03488  0.00056  43  GLY A CA  
269  C  C   . GLY A 20  ? 0.17739 0.18630 0.09273 -0.01559 0.05058  0.00959  43  GLY A C   
270  O  O   . GLY A 20  ? 0.21885 0.20438 0.10448 -0.00848 0.04771  0.00318  43  GLY A O   
274  N  N   . ARG A 21  ? 0.13523 0.19825 0.09538 -0.01184 0.04495  -0.00427 44  ARG A N   
275  C  CA  . ARG A 21  ? 0.14460 0.17267 0.10257 -0.00317 0.04997  0.01129  44  ARG A CA  
276  C  C   . ARG A 21  ? 0.14260 0.17751 0.10498 0.00460  0.02224  0.00130  44  ARG A C   
277  O  O   . ARG A 21  ? 0.13634 0.17184 0.10366 -0.00766 0.01595  0.00482  44  ARG A O   
278  C  CB  . ARG A 21  ? 0.13485 0.17740 0.11790 -0.02194 0.03335  -0.00454 44  ARG A CB  
279  C  CG  . ARG A 21  ? 0.13768 0.20045 0.12321 -0.01649 0.02320  -0.00377 44  ARG A CG  
280  C  CD  . ARG A 21  ? 0.14297 0.20330 0.12287 -0.01217 0.01807  -0.00881 44  ARG A CD  
281  N  NE  . ARG A 21  ? 0.15554 0.19937 0.11611 -0.00796 0.02282  -0.00861 44  ARG A NE  
282  C  CZ  . ARG A 21  ? 0.12354 0.19841 0.11222 -0.03263 0.01393  -0.01638 44  ARG A CZ  
283  N  NH1 . ARG A 21  ? 0.13650 0.19448 0.13232 -0.01200 0.03560  -0.00137 44  ARG A NH1 
284  N  NH2 . ARG A 21  ? 0.13393 0.19919 0.12318 -0.00178 0.01197  -0.00381 44  ARG A NH2 
298  N  N   . LEU A 22  ? 0.13163 0.17067 0.11184 -0.00436 0.03540  0.00123  45  LEU A N   
299  C  CA  . LEU A 22  ? 0.13164 0.16397 0.10529 -0.00716 0.03348  0.01078  45  LEU A CA  
300  C  C   . LEU A 22  ? 0.13986 0.15383 0.10341 -0.00845 0.03361  -0.00066 45  LEU A C   
301  O  O   . LEU A 22  ? 0.14714 0.17949 0.13347 0.02106  0.03660  0.00267  45  LEU A O   
302  C  CB  . LEU A 22  ? 0.16795 0.17946 0.10911 -0.02149 0.03316  0.00044  45  LEU A CB  
303  C  CG  . LEU A 22  ? 0.17471 0.20735 0.11182 -0.02754 0.02063  -0.00481 45  LEU A CG  
304  C  CD1 . LEU A 22  ? 0.17121 0.23415 0.11374 -0.04574 0.00478  -0.01052 45  LEU A CD1 
305  C  CD2 . LEU A 22  ? 0.18871 0.22022 0.11795 -0.04037 0.00435  -0.02613 45  LEU A CD2 
317  N  N   . GLY A 23  ? 0.11530 0.16496 0.09143 -0.00505 0.01664  -0.00193 46  GLY A N   
318  C  CA  . GLY A 23  ? 0.12287 0.14673 0.09278 -0.00096 0.01500  0.01734  46  GLY A CA  
319  C  C   . GLY A 23  ? 0.12587 0.14697 0.09816 0.01171  0.01233  0.00819  46  GLY A C   
320  O  O   . GLY A 23  ? 0.11889 0.15003 0.11707 0.00842  0.01350  0.01714  46  GLY A O   
324  N  N   . VAL A 24  ? 0.11962 0.14714 0.10447 0.01061  0.01410  0.00188  47  VAL A N   
325  C  CA  . VAL A 24  ? 0.11836 0.13834 0.10886 0.00512  0.01682  -0.00169 47  VAL A CA  
326  C  C   . VAL A 24  ? 0.11674 0.15217 0.10436 0.00735  0.02126  -0.00453 47  VAL A C   
327  O  O   . VAL A 24  ? 0.13295 0.15138 0.11679 0.00538  0.02512  -0.00292 47  VAL A O   
328  C  CB  . VAL A 24  ? 0.13534 0.14859 0.11093 -0.01431 0.01269  -0.01408 47  VAL A CB  
329  C  CG1 . VAL A 24  ? 0.15782 0.19778 0.10689 0.00362  0.00763  -0.01849 47  VAL A CG1 
330  C  CG2 . VAL A 24  ? 0.15102 0.18244 0.10870 -0.00938 0.00625  -0.00515 47  VAL A CG2 
340  N  N   . ALA A 25  ? 0.12845 0.15623 0.09203 0.01687  0.00759  -0.00161 48  ALA A N   
341  C  CA  . ALA A 25  ? 0.13833 0.15309 0.09620 0.00717  0.00683  0.00014  48  ALA A CA  
342  C  C   . ALA A 25  ? 0.14746 0.11579 0.09151 0.01138  -0.00506 -0.00415 48  ALA A C   
343  O  O   . ALA A 25  ? 0.14297 0.12427 0.10643 0.00744  0.00931  -0.00031 48  ALA A O   
344  C  CB  . ALA A 25  ? 0.13860 0.13078 0.11147 0.00178  0.00058  -0.00455 48  ALA A CB  
350  N  N   . LEU A 26  ? 0.14819 0.13793 0.09773 0.01972  0.00088  -0.00564 49  LEU A N   
351  C  CA  . LEU A 26  ? 0.14098 0.13475 0.10932 -0.01055 -0.00068 0.00900  49  LEU A CA  
352  C  C   . LEU A 26  ? 0.15408 0.13638 0.13115 0.00421  0.00099  0.01146  49  LEU A C   
353  O  O   . LEU A 26  ? 0.15926 0.15797 0.14716 0.01975  0.00831  0.02772  49  LEU A O   
354  C  CB  . LEU A 26  ? 0.14474 0.15856 0.12673 -0.00345 0.00833  0.00549  49  LEU A CB  
355  C  CG  . LEU A 26  ? 0.16428 0.18202 0.13481 -0.01547 -0.02183 -0.00746 49  LEU A CG  
356  C  CD1 . LEU A 26  ? 0.18991 0.19231 0.14526 -0.01647 -0.02365 -0.01337 49  LEU A CD1 
357  C  CD2 . LEU A 26  ? 0.24440 0.20171 0.16108 0.00959  -0.00297 -0.01401 49  LEU A CD2 
369  N  N   . ILE A 27  ? 0.15554 0.13132 0.12411 -0.00806 0.01019  0.00340  50  ILE A N   
370  C  CA  . ILE A 27  ? 0.17247 0.12852 0.11867 -0.01894 0.01243  0.00804  50  ILE A CA  
371  C  C   . ILE A 27  ? 0.18321 0.14244 0.11642 -0.03130 0.00838  0.01238  50  ILE A C   
372  O  O   . ILE A 27  ? 0.18319 0.15348 0.13223 -0.01322 -0.00764 0.01051  50  ILE A O   
373  C  CB  . ILE A 27  ? 0.16774 0.14776 0.11558 -0.01155 -0.00717 0.00580  50  ILE A CB  
374  C  CG1 . ILE A 27  ? 0.19167 0.17174 0.10008 -0.00383 -0.03242 0.00476  50  ILE A CG1 
375  C  CG2 . ILE A 27  ? 0.16283 0.17028 0.13618 -0.01889 0.00769  0.02445  50  ILE A CG2 
376  C  CD1 . ILE A 27  ? 0.23654 0.16850 0.09853 -0.00664 -0.04338 0.01994  50  ILE A CD1 
388  N  N   . ASN A 28  ? 0.21825 0.14108 0.12525 -0.04252 -0.00692 0.00003  51  ASN A N   
389  C  CA  . ASN A 28  ? 0.24381 0.14334 0.13546 -0.04352 -0.02676 0.00996  51  ASN A CA  
390  C  C   . ASN A 28  ? 0.26630 0.15790 0.14463 -0.05235 -0.01947 0.02776  51  ASN A C   
391  O  O   . ASN A 28  ? 0.28723 0.16255 0.15362 -0.03754 -0.01511 0.02101  51  ASN A O   
392  C  CB  . ASN A 28  ? 0.26476 0.17717 0.15485 -0.03140 -0.02880 -0.00600 51  ASN A CB  
393  C  CG  . ASN A 28  ? 0.29619 0.20482 0.17188 -0.04797 -0.02290 -0.01626 51  ASN A CG  
394  O  OD1 . ASN A 28  ? 0.29136 0.19024 0.16859 -0.05794 -0.01621 -0.00130 51  ASN A OD1 
395  N  ND2 . ASN A 28  ? 0.34342 0.25373 0.19391 -0.06182 -0.02973 -0.04100 51  ASN A ND2 
402  N  N   . THR A 29  ? 0.25072 0.20145 0.14101 -0.06307 -0.01298 0.03151  52  THR A N   
403  C  CA  . THR A 29  ? 0.27054 0.19696 0.16049 -0.07523 -0.01941 0.03822  52  THR A CA  
404  C  C   . THR A 29  ? 0.33761 0.20351 0.19800 -0.09003 -0.01020 0.04296  52  THR A C   
405  O  O   . THR A 29  ? 0.36637 0.22253 0.19544 -0.09689 -0.01076 0.08002  52  THR A O   
406  C  CB  . THR A 29  ? 0.23747 0.23470 0.14890 -0.06773 -0.02871 0.03049  52  THR A CB  
407  O  OG1 . THR A 29  ? 0.26067 0.24537 0.15626 -0.09079 -0.03328 0.06904  52  THR A OG1 
408  C  CG2 . THR A 29  ? 0.20624 0.24016 0.14598 -0.02204 -0.02567 -0.00215 52  THR A CG2 
416  N  N   . ALA A 30  ? 0.34079 0.20279 0.23018 -0.11572 -0.01233 0.02959  53  ALA A N   
417  C  CA  . ALA A 30  ? 0.37585 0.19988 0.25592 -0.11112 0.01312  0.03542  53  ALA A CA  
418  C  C   . ALA A 30  ? 0.40528 0.20246 0.26617 -0.07846 0.01542  0.04968  53  ALA A C   
419  O  O   . ALA A 30  ? 0.42861 0.21686 0.27805 -0.11113 -0.00361 0.05014  53  ALA A O   
420  C  CB  . ALA A 30  ? 0.38603 0.20255 0.26897 -0.12945 -0.00116 0.02302  53  ALA A CB  
426  N  N   . ASP A 31  ? 0.39805 0.18582 0.26798 -0.05343 0.03494  0.04956  54  ASP A N   
427  C  CA  . ASP A 31  ? 0.39996 0.21315 0.27287 -0.03429 0.05103  0.03278  54  ASP A CA  
428  C  C   . ASP A 31  ? 0.32796 0.19667 0.26280 -0.00290 0.05954  0.07045  54  ASP A C   
429  O  O   . ASP A 31  ? 0.32429 0.21433 0.26273 0.01983  0.06149  0.07928  54  ASP A O   
430  C  CB  . ASP A 31  ? 0.45383 0.23958 0.29486 -0.05519 0.06286  -0.01704 54  ASP A CB  
431  C  CG  . ASP A 31  ? 0.49904 0.29383 0.30292 -0.04056 0.06590  -0.04543 54  ASP A CG  
432  O  OD1 . ASP A 31  ? 0.47038 0.24233 0.29622 -0.07452 0.06861  -0.04240 54  ASP A OD1 
433  O  OD2 . ASP A 31  ? 0.55765 0.31816 0.31352 -0.05079 0.05622  -0.06919 54  ASP A OD2 
438  N  N   . ASN A 32  ? 0.28034 0.17123 0.24123 0.01231  0.05731  0.06636  55  ASN A N   
439  C  CA  . ASN A 32  ? 0.25221 0.21110 0.22358 0.02763  0.06357  0.07595  55  ASN A CA  
440  C  C   . ASN A 32  ? 0.26271 0.21870 0.22308 0.04998  0.07630  0.07615  55  ASN A C   
441  O  O   . ASN A 32  ? 0.26962 0.27485 0.23840 0.02244  0.07622  0.05103  55  ASN A O   
442  C  CB  . ASN A 32  ? 0.26349 0.27054 0.21401 0.02937  0.03545  0.08823  55  ASN A CB  
443  C  CG  . ASN A 32  ? 0.27791 0.33139 0.19937 0.02931  0.04416  0.06712  55  ASN A CG  
444  O  OD1 . ASN A 32  ? 0.27037 0.30994 0.18898 0.01624  0.04474  0.04658  55  ASN A OD1 
445  N  ND2 . ASN A 32  ? 0.25718 0.36811 0.19301 0.05942  0.04490  0.04417  55  ASN A ND2 
452  N  N   . SER A 33  ? 0.28963 0.18230 0.21639 0.04936  0.07880  0.08558  56  SER A N   
453  C  CA  . SER A 33  ? 0.30789 0.16923 0.22395 0.04668  0.08590  0.05669  56  SER A CA  
454  C  C   . SER A 33  ? 0.26906 0.16342 0.21224 0.02937  0.07586  0.05413  56  SER A C   
455  O  O   . SER A 33  ? 0.25262 0.15011 0.19481 0.02095  0.06146  0.04659  56  SER A O   
456  C  CB  . SER A 33  ? 0.35925 0.18812 0.23448 0.04115  0.08484  0.04053  56  SER A CB  
457  O  OG  . SER A 33  ? 0.42254 0.19545 0.24158 0.00160  0.05841  0.03397  56  SER A OG  
463  N  N   . GLN A 34  ? 0.25060 0.18727 0.21270 0.07767  0.08755  0.05667  57  GLN A N   
464  C  CA  . GLN A 34  ? 0.24003 0.15659 0.20967 0.04990  0.07978  0.05171  57  GLN A CA  
465  C  C   . GLN A 34  ? 0.24970 0.15480 0.19838 0.04278  0.06812  0.02653  57  GLN A C   
466  O  O   . GLN A 34  ? 0.29116 0.19610 0.20910 0.04952  0.07948  0.05385  57  GLN A O   
467  C  CB  . GLN A 34  ? 0.28581 0.19971 0.21379 0.01523  0.08009  0.05373  57  GLN A CB  
468  C  CG  . GLN A 34  ? 0.36376 0.26781 0.25102 0.02026  0.05699  0.05878  57  GLN A CG  
469  C  CD  . GLN A 34  ? 0.42414 0.29519 0.29213 0.02021  0.03134  0.04678  57  GLN A CD  
470  O  OE1 . GLN A 34  ? 0.46134 0.33544 0.30761 0.00279  0.04503  0.05581  57  GLN A OE1 
471  N  NE2 . GLN A 34  ? 0.45663 0.36986 0.30606 0.00093  0.00058  0.03393  57  GLN A NE2 
480  N  N   . ILE A 35  ? 0.20693 0.13592 0.17026 0.01757  0.04469  0.01628  58  ILE A N   
481  C  CA  . ILE A 35  ? 0.18177 0.15339 0.15509 0.02971  0.02626  0.01699  58  ILE A CA  
482  C  C   . ILE A 35  ? 0.17308 0.15758 0.14545 0.03154  0.04578  0.00324  58  ILE A C   
483  O  O   . ILE A 35  ? 0.17602 0.13958 0.15171 0.01901  0.02922  0.00055  58  ILE A O   
484  C  CB  . ILE A 35  ? 0.19825 0.19161 0.15615 0.00959  0.02944  -0.00052 58  ILE A CB  
485  C  CG1 . ILE A 35  ? 0.25165 0.25581 0.16491 -0.02961 0.01692  -0.01377 58  ILE A CG1 
486  C  CG2 . ILE A 35  ? 0.20707 0.23976 0.15392 -0.00190 0.02112  -0.00183 58  ILE A CG2 
487  C  CD1 . ILE A 35  ? 0.29175 0.29247 0.17281 -0.03826 0.00662  -0.01593 58  ILE A CD1 
499  N  N   . LEU A 36  ? 0.17231 0.15505 0.15475 0.03731  0.03422  -0.02327 59  LEU A N   
500  C  CA  . LEU A 36  ? 0.16093 0.16766 0.16440 0.04506  0.03904  -0.01775 59  LEU A CA  
501  C  C   . LEU A 36  ? 0.16616 0.16710 0.16440 0.01202  0.04207  -0.02411 59  LEU A C   
502  O  O   . LEU A 36  ? 0.20211 0.17812 0.19452 0.01551  0.06998  -0.01753 59  LEU A O   
503  C  CB  . LEU A 36  ? 0.16049 0.17478 0.18604 0.00681  0.02611  -0.01212 59  LEU A CB  
504  C  CG  . LEU A 36  ? 0.17872 0.20540 0.19500 -0.00282 0.02308  0.00635  59  LEU A CG  
505  C  CD1 . LEU A 36  ? 0.22660 0.27475 0.20792 0.00714  0.00427  0.02411  59  LEU A CD1 
506  C  CD2 . LEU A 36  ? 0.21312 0.18388 0.18065 0.00579  0.05496  0.00790  59  LEU A CD2 
518  N  N   . TYR A 37  ? 0.14147 0.16641 0.14173 0.01134  0.04545  -0.01335 60  TYR A N   
519  C  CA  . TYR A 37  ? 0.12827 0.17838 0.13336 0.00286  0.03439  -0.00758 60  TYR A CA  
520  C  C   . TYR A 37  ? 0.11282 0.18756 0.12992 -0.00185 0.03684  -0.00429 60  TYR A C   
521  O  O   . TYR A 37  ? 0.12627 0.17237 0.13097 -0.00124 0.03350  0.00176  60  TYR A O   
522  C  CB  . TYR A 37  ? 0.15892 0.18446 0.13639 0.01173  0.02137  -0.01647 60  TYR A CB  
523  C  CG  . TYR A 37  ? 0.16457 0.19995 0.13553 0.03155  0.04121  -0.00888 60  TYR A CG  
524  C  CD1 . TYR A 37  ? 0.20051 0.20348 0.14310 0.02431  0.04434  -0.01263 60  TYR A CD1 
525  C  CD2 . TYR A 37  ? 0.17125 0.20590 0.12497 0.02221  0.02988  -0.01099 60  TYR A CD2 
526  C  CE1 . TYR A 37  ? 0.20544 0.21255 0.16205 0.03588  0.05865  -0.01174 60  TYR A CE1 
527  C  CE2 . TYR A 37  ? 0.18670 0.20499 0.13177 0.00240  0.05480  -0.01489 60  TYR A CE2 
528  C  CZ  . TYR A 37  ? 0.20673 0.22156 0.14836 0.02313  0.07151  -0.00667 60  TYR A CZ  
529  O  OH  . TYR A 37  ? 0.23547 0.24642 0.15266 0.01610  0.09802  -0.00823 60  TYR A OH  
539  N  N   . ARG A 38  ? 0.12879 0.18337 0.13109 0.01820  0.03901  -0.01655 61  ARG A N   
540  C  CA  . ARG A 38  ? 0.14101 0.17128 0.14017 0.00917  0.02418  -0.01639 61  ARG A CA  
541  C  C   . ARG A 38  ? 0.14044 0.14982 0.13640 0.01300  0.02336  -0.02120 61  ARG A C   
542  O  O   . ARG A 38  ? 0.13497 0.16582 0.14969 0.00822  0.02350  -0.01226 61  ARG A O   
543  C  CB  . ARG A 38  ? 0.13526 0.16228 0.14365 -0.00309 0.02342  -0.00711 61  ARG A CB  
544  C  CG  . ARG A 38  ? 0.13711 0.20875 0.14673 0.00023  0.03121  -0.01150 61  ARG A CG  
545  C  CD  . ARG A 38  ? 0.14906 0.22029 0.15132 -0.01856 0.05438  0.00297  61  ARG A CD  
546  N  NE  . ARG A 38  ? 0.16175 0.23763 0.15623 0.01508  0.05806  0.00381  61  ARG A NE  
547  C  CZ  . ARG A 38  ? 0.16389 0.28240 0.16048 0.01185  0.05325  -0.00219 61  ARG A CZ  
548  N  NH1 . ARG A 38  ? 0.15715 0.31136 0.17408 -0.00947 0.05665  -0.01508 61  ARG A NH1 
549  N  NH2 . ARG A 38  ? 0.19414 0.32605 0.16458 0.01221  0.06607  -0.00391 61  ARG A NH2 
563  N  N   . ALA A 39  ? 0.14578 0.16344 0.13879 0.02869  0.02947  -0.00567 62  ALA A N   
564  C  CA  . ALA A 39  ? 0.13429 0.16477 0.13070 0.00625  0.02708  -0.00340 62  ALA A CA  
565  C  C   . ALA A 39  ? 0.14205 0.17254 0.12413 0.01946  0.00699  -0.00606 62  ALA A C   
566  O  O   . ALA A 39  ? 0.15453 0.17920 0.12489 0.01723  0.02340  -0.01417 62  ALA A O   
567  C  CB  . ALA A 39  ? 0.18792 0.16068 0.12901 -0.00487 0.02238  -0.01222 62  ALA A CB  
573  N  N   . ASP A 40  ? 0.13847 0.18694 0.13047 0.01644  -0.00036 -0.00146 63  ASP A N   
574  C  CA  . ASP A 40  ? 0.15826 0.18523 0.13903 0.00065  -0.01389 0.00395  63  ASP A CA  
575  C  C   . ASP A 40  ? 0.15641 0.18210 0.13561 0.01058  -0.01645 -0.00372 63  ASP A C   
576  O  O   . ASP A 40  ? 0.21421 0.21350 0.14583 -0.00184 -0.03261 -0.01059 63  ASP A O   
577  C  CB  . ASP A 40  ? 0.17217 0.21503 0.15552 0.01874  -0.02015 0.01365  63  ASP A CB  
578  C  CG  . ASP A 40  ? 0.22392 0.23790 0.18174 0.03533  -0.00877 0.01836  63  ASP A CG  
579  O  OD1 . ASP A 40  ? 0.23744 0.24259 0.18039 0.03952  0.00645  0.01193  63  ASP A OD1 
580  O  OD2 . ASP A 40  ? 0.25313 0.23422 0.20188 0.04440  0.00082  0.02576  63  ASP A OD2 
585  N  N   . GLU A 41  ? 0.13321 0.17987 0.13110 -0.00044 -0.00519 -0.01304 64  GLU A N   
586  C  CA  . GLU A 41  ? 0.12667 0.16565 0.13488 -0.00585 0.02982  -0.00986 64  GLU A CA  
587  C  C   . GLU A 41  ? 0.11511 0.17518 0.12405 -0.01607 0.01443  0.00921  64  GLU A C   
588  O  O   . GLU A 41  ? 0.15266 0.18052 0.13217 -0.01827 0.01996  -0.01368 64  GLU A O   
589  C  CB  . GLU A 41  ? 0.13004 0.18972 0.15503 -0.00203 0.03622  -0.00669 64  GLU A CB  
590  C  CG  . GLU A 41  ? 0.13684 0.22546 0.16665 0.01676  0.04831  -0.00679 64  GLU A CG  
591  C  CD  . GLU A 41  ? 0.16043 0.22541 0.16893 0.02735  0.03826  -0.01045 64  GLU A CD  
592  O  OE1 . GLU A 41  ? 0.21319 0.22272 0.16919 0.02126  0.06596  0.01286  64  GLU A OE1 
593  O  OE2 . GLU A 41  ? 0.16793 0.25936 0.16244 0.05110  0.03599  -0.03125 64  GLU A OE2 
600  N  N   . ARG A 42  ? 0.11625 0.16642 0.12691 -0.00351 0.01295  0.00962  65  ARG A N   
601  C  CA  . ARG A 42  ? 0.10426 0.17112 0.12143 0.00098  -0.00001 0.00511  65  ARG A CA  
602  C  C   . ARG A 42  ? 0.09569 0.17093 0.11176 -0.00454 0.02306  -0.02306 65  ARG A C   
603  O  O   . ARG A 42  ? 0.10989 0.18947 0.11706 -0.00037 0.02208  -0.00667 65  ARG A O   
604  C  CB  . ARG A 42  ? 0.12436 0.20266 0.10598 -0.00256 0.00499  -0.01077 65  ARG A CB  
605  C  CG  . ARG A 42  ? 0.16086 0.21254 0.11049 -0.01102 -0.00434 0.00637  65  ARG A CG  
606  C  CD  . ARG A 42  ? 0.13669 0.25496 0.11845 -0.02345 -0.01239 0.00031  65  ARG A CD  
607  N  NE  . ARG A 42  ? 0.12797 0.28177 0.13429 -0.01463 0.01216  -0.00457 65  ARG A NE  
608  C  CZ  . ARG A 42  ? 0.12142 0.25692 0.13421 -0.01589 0.02092  -0.00625 65  ARG A CZ  
609  N  NH1 . ARG A 42  ? 0.11480 0.20618 0.12680 0.00558  0.01511  0.01535  65  ARG A NH1 
610  N  NH2 . ARG A 42  ? 0.18521 0.28003 0.15152 -0.00846 -0.00433 0.01940  65  ARG A NH2 
624  N  N   . PHE A 43  ? 0.11818 0.15774 0.10265 -0.01617 0.00968  -0.00242 66  PHE A N   
625  C  CA  . PHE A 43  ? 0.11408 0.15328 0.09664 -0.01028 0.01656  -0.00644 66  PHE A CA  
626  C  C   . PHE A 43  ? 0.13319 0.14426 0.08524 -0.02789 0.01423  -0.00554 66  PHE A C   
627  O  O   . PHE A 43  ? 0.12218 0.15514 0.08292 -0.01909 0.00994  -0.00505 66  PHE A O   
628  C  CB  . PHE A 43  ? 0.09854 0.16885 0.09924 -0.01481 0.02291  -0.01498 66  PHE A CB  
629  C  CG  . PHE A 43  ? 0.12579 0.15344 0.10457 -0.02905 0.01873  -0.03064 66  PHE A CG  
630  C  CD1 . PHE A 43  ? 0.13540 0.16959 0.11010 -0.03986 0.01867  -0.02663 66  PHE A CD1 
631  C  CD2 . PHE A 43  ? 0.14740 0.16638 0.10811 -0.03416 0.04524  -0.01610 66  PHE A CD2 
632  C  CE1 . PHE A 43  ? 0.14152 0.15557 0.11059 -0.02189 0.03269  -0.03117 66  PHE A CE1 
633  C  CE2 . PHE A 43  ? 0.14718 0.17323 0.11928 -0.03303 0.03066  -0.02302 66  PHE A CE2 
634  C  CZ  . PHE A 43  ? 0.14610 0.15683 0.11520 -0.02014 0.01498  -0.02599 66  PHE A CZ  
644  N  N   . ALA A 44  ? 0.11829 0.15724 0.08885 -0.01319 0.02980  -0.00043 67  ALA A N   
645  C  CA  . ALA A 44  ? 0.11301 0.15271 0.08304 -0.02252 0.02241  -0.00590 67  ALA A CA  
646  C  C   . ALA A 44  ? 0.12184 0.15390 0.08057 -0.01519 0.00904  -0.00816 67  ALA A C   
647  O  O   . ALA A 44  ? 0.12590 0.19061 0.07422 -0.02939 0.00759  -0.02332 67  ALA A O   
648  C  CB  . ALA A 44  ? 0.13039 0.17631 0.09542 -0.03204 0.01091  -0.00452 67  ALA A CB  
654  N  N   . MET A 45  ? 0.08647 0.14717 0.08708 -0.00703 0.01258  -0.01355 68  MET A N   
655  C  CA  . MET A 45  ? 0.09431 0.13746 0.08195 -0.01345 0.00971  -0.00771 68  MET A CA  
656  C  C   . MET A 45  ? 0.09071 0.15309 0.07963 -0.02651 0.01464  -0.02034 68  MET A C   
657  O  O   . MET A 45  ? 0.09905 0.14891 0.07259 -0.01732 0.00856  -0.00525 68  MET A O   
658  C  CB  . MET A 45  ? 0.10899 0.15865 0.07881 -0.02295 0.00097  -0.00126 68  MET A CB  
659  C  CG  . MET A 45  ? 0.11294 0.17012 0.09471 -0.01016 0.00966  -0.00685 68  MET A CG  
660  S  SD  . MET A 45  ? 0.12049 0.15915 0.08996 -0.01132 0.00574  -0.00235 68  MET A SD  
661  C  CE  . MET A 45  ? 0.12302 0.17378 0.09677 -0.01339 0.01618  -0.00853 68  MET A CE  
671  N  N   . CYS A 46  ? 0.11903 0.13999 0.07868 -0.02194 0.01067  -0.01345 69  CYS A N   
672  C  CA  . CYS A 46  ? 0.09296 0.13167 0.08521 0.00191  0.01371  -0.01215 69  CYS A CA  
673  C  C   . CYS A 46  ? 0.10972 0.12795 0.09002 -0.01221 0.00460  -0.00212 69  CYS A C   
674  O  O   . CYS A 46  ? 0.13325 0.13781 0.08682 -0.00794 0.00908  0.00437  69  CYS A O   
675  C  CB  . CYS A 46  ? 0.12167 0.15057 0.09508 -0.01313 0.01184  -0.00207 69  CYS A CB  
676  S  SG  . CYS A 46  ? 0.12400 0.18418 0.09124 -0.01833 0.01871  0.00476  69  CYS A SG  
682  N  N   . SER A 47  ? 0.08631 0.16101 0.08792 -0.00712 0.01653  -0.01323 70  SER A N   
683  C  CA  . SER A 47  ? 0.09597 0.12859 0.09906 0.00170  0.00519  -0.00922 70  SER A CA  
684  C  C   . SER A 47  ? 0.09700 0.16050 0.10068 -0.00104 0.01417  -0.01276 70  SER A C   
685  O  O   . SER A 47  ? 0.10182 0.15359 0.09929 -0.00746 0.02070  -0.01342 70  SER A O   
686  C  CB  . SER A 47  ? 0.11245 0.16064 0.10295 -0.01892 0.00507  -0.01046 70  SER A CB  
687  O  OG  . SER A 47  ? 0.13802 0.14913 0.11541 -0.00290 0.01829  -0.00417 70  SER A OG  
692  N  N   . THR A 48  ? 0.11740 0.14829 0.08653 -0.00630 0.00566  0.00147  71  THR A N   
693  C  CA  . THR A 48  ? 0.10757 0.14128 0.08325 -0.01611 0.01905  -0.00669 71  THR A CA  
694  C  C   . THR A 48  ? 0.10277 0.13123 0.09709 -0.01704 0.01346  -0.01364 71  THR A C   
695  O  O   . THR A 48  ? 0.12438 0.14467 0.09490 -0.01981 0.02436  -0.00553 71  THR A O   
696  C  CB  . THR A 48  ? 0.10766 0.14648 0.08501 -0.01368 0.01256  -0.00072 71  THR A CB  
697  O  OG1 . THR A 48  ? 0.10433 0.15041 0.09373 -0.01340 0.00591  0.00380  71  THR A OG1 
698  C  CG2 . THR A 48  ? 0.12390 0.14322 0.08542 -0.01272 0.02237  -0.00911 71  THR A CG2 
706  N  N   . SER A 49  ? 0.10248 0.14141 0.09250 -0.01016 0.02086  -0.00600 72  SER A N   
707  C  CA  . SER A 49  ? 0.10337 0.15414 0.07861 -0.00854 0.00412  -0.01206 72  SER A CA  
708  C  C   . SER A 49  ? 0.10999 0.14344 0.08223 -0.01242 0.01124  -0.02371 72  SER A C   
709  O  O   . SER A 49  ? 0.12419 0.15633 0.07933 -0.01261 0.01435  -0.01911 72  SER A O   
710  C  CB  . SER A 49  ? 0.12152 0.17240 0.09311 -0.00137 0.01359  -0.00253 72  SER A CB  
711  O  OG  . SER A 49  ? 0.12832 0.15948 0.08144 -0.02779 0.02491  -0.01398 72  SER A OG  
717  N  N   . LYS A 50  ? 0.09847 0.15624 0.07924 -0.01407 0.02203  -0.01375 73  LYS A N   
718  C  CA  . LYS A 50  ? 0.10817 0.14678 0.09424 -0.01590 -0.00175 -0.00668 73  LYS A CA  
719  C  C   . LYS A 50  ? 0.09889 0.14428 0.09364 -0.02030 0.01581  -0.00697 73  LYS A C   
720  O  O   . LYS A 50  ? 0.09430 0.15963 0.08541 -0.00973 0.02277  -0.00321 73  LYS A O   
721  C  CB  . LYS A 50  ? 0.08728 0.15730 0.09679 -0.00295 0.00422  -0.01327 73  LYS A CB  
722  C  CG  . LYS A 50  ? 0.13428 0.14053 0.09246 -0.01959 0.01935  -0.01801 73  LYS A CG  
723  C  CD  . LYS A 50  ? 0.13536 0.16069 0.09104 -0.00735 0.02006  -0.00297 73  LYS A CD  
724  C  CE  . LYS A 50  ? 0.14963 0.16143 0.09541 -0.00659 0.01286  -0.00923 73  LYS A CE  
725  N  NZ  . LYS A 50  ? 0.14237 0.15650 0.11276 0.00797  0.00385  0.00250  73  LYS A NZ  
739  N  N   . VAL A 51  ? 0.11604 0.13029 0.09502 -0.02148 0.01094  -0.01319 74  VAL A N   
740  C  CA  . VAL A 51  ? 0.11124 0.14482 0.10127 -0.01027 0.00252  -0.00802 74  VAL A CA  
741  C  C   . VAL A 51  ? 0.09016 0.14724 0.10575 -0.00868 -0.00640 -0.00500 74  VAL A C   
742  O  O   . VAL A 51  ? 0.10683 0.15644 0.09142 -0.01878 0.02183  0.00540  74  VAL A O   
743  C  CB  . VAL A 51  ? 0.11961 0.15085 0.10293 -0.00798 0.01177  -0.00886 74  VAL A CB  
744  C  CG1 . VAL A 51  ? 0.15825 0.14675 0.10491 -0.01153 0.01286  0.00564  74  VAL A CG1 
745  C  CG2 . VAL A 51  ? 0.12550 0.15996 0.11226 -0.01348 0.02963  -0.00774 74  VAL A CG2 
755  N  N   A MET A 52  ? 0.09689 0.16894 0.10544 -0.00961 0.00189  0.00822  75  MET A N   
756  N  N   B MET A 52  ? 0.09020 0.15892 0.10573 -0.02167 0.00361  0.00272  75  MET A N   
757  C  CA  A MET A 52  ? 0.09966 0.17531 0.10752 -0.00605 -0.00229 0.00995  75  MET A CA  
758  C  CA  B MET A 52  ? 0.08325 0.15322 0.10760 -0.01795 -0.00023 -0.00742 75  MET A CA  
759  C  C   A MET A 52  ? 0.09494 0.17408 0.09876 -0.01401 0.00307  0.00527  75  MET A C   
760  C  C   B MET A 52  ? 0.08241 0.17368 0.10247 -0.01059 0.00749  -0.00249 75  MET A C   
761  O  O   A MET A 52  ? 0.10604 0.18247 0.09295 -0.02117 0.00036  -0.00197 75  MET A O   
762  O  O   B MET A 52  ? 0.10992 0.18538 0.10080 -0.01457 0.00309  -0.00698 75  MET A O   
763  C  CB  A MET A 52  ? 0.10802 0.17818 0.12030 0.00152  0.00306  0.01977  75  MET A CB  
764  C  CB  B MET A 52  ? 0.09176 0.13292 0.11857 -0.00726 0.00367  -0.01287 75  MET A CB  
765  C  CG  A MET A 52  ? 0.11659 0.20149 0.13850 -0.01583 -0.00471 0.03010  75  MET A CG  
766  C  CG  B MET A 52  ? 0.11594 0.14979 0.13313 -0.01044 -0.00652 -0.01465 75  MET A CG  
767  S  SD  A MET A 52  ? 0.17807 0.19463 0.15631 0.00813  -0.00648 0.04134  75  MET A SD  
768  S  SD  B MET A 52  ? 0.11962 0.15180 0.15641 -0.00850 -0.03057 -0.00646 75  MET A SD  
769  C  CE  A MET A 52  ? 0.15524 0.19785 0.16198 0.03972  0.00512  0.04013  75  MET A CE  
770  C  CE  B MET A 52  ? 0.14625 0.13629 0.14701 -0.01666 -0.08704 0.01267  75  MET A CE  
789  N  N   . ALA A 53  ? 0.11035 0.16354 0.08948 -0.01361 0.00504  -0.00120 76  ALA A N   
790  C  CA  . ALA A 53  ? 0.12175 0.16675 0.09150 -0.00331 -0.00484 -0.00676 76  ALA A CA  
791  C  C   . ALA A 53  ? 0.10078 0.18062 0.09487 0.01036  0.00399  -0.00261 76  ALA A C   
792  O  O   . ALA A 53  ? 0.12400 0.17193 0.09677 -0.00512 0.00901  -0.01003 76  ALA A O   
793  C  CB  . ALA A 53  ? 0.14121 0.16618 0.10502 -0.01597 0.01305  -0.00008 76  ALA A CB  
800  N  N   . ALA A 54  ? 0.11060 0.15886 0.08689 0.01531  0.00654  -0.00367 77  ALA A N   
801  C  CA  . ALA A 54  ? 0.10526 0.16636 0.09359 0.00610  0.00066  -0.00460 77  ALA A CA  
802  C  C   . ALA A 54  ? 0.10915 0.17450 0.09565 0.01332  0.00568  -0.00779 77  ALA A C   
803  O  O   . ALA A 54  ? 0.11269 0.21070 0.08841 0.01845  0.01629  -0.00260 77  ALA A O   
804  C  CB  . ALA A 54  ? 0.12191 0.17643 0.10435 0.00128  0.01541  0.00030  77  ALA A CB  
810  N  N   . ALA A 55  ? 0.10224 0.16435 0.09210 0.00718  0.00214  -0.00421 78  ALA A N   
811  C  CA  . ALA A 55  ? 0.12476 0.15100 0.08534 -0.01630 0.00188  -0.00313 78  ALA A CA  
812  C  C   . ALA A 55  ? 0.10604 0.17204 0.08663 0.00788  -0.00153 0.00142  78  ALA A C   
813  O  O   . ALA A 55  ? 0.12245 0.16975 0.08137 0.01079  -0.00342 -0.00523 78  ALA A O   
814  C  CB  . ALA A 55  ? 0.12704 0.17289 0.08602 -0.00395 0.00847  -0.00147 78  ALA A CB  
820  N  N   . ALA A 56  ? 0.11726 0.16383 0.08631 0.00333  -0.01103 -0.00816 79  ALA A N   
821  C  CA  . ALA A 56  ? 0.13707 0.16566 0.10056 0.01553  -0.01310 -0.01271 79  ALA A CA  
822  C  C   . ALA A 56  ? 0.12798 0.18311 0.09590 0.01303  -0.01806 -0.01947 79  ALA A C   
823  O  O   . ALA A 56  ? 0.19433 0.18012 0.09171 0.03103  -0.00661 -0.01418 79  ALA A O   
824  C  CB  . ALA A 56  ? 0.16423 0.20665 0.11459 0.02120  -0.02865 -0.01903 79  ALA A CB  
830  N  N   . VAL A 57  ? 0.13959 0.17530 0.10884 0.01099  -0.00508 -0.01672 80  VAL A N   
831  C  CA  . VAL A 57  ? 0.15847 0.16817 0.11474 0.00859  0.00473  -0.01906 80  VAL A CA  
832  C  C   . VAL A 57  ? 0.14017 0.20142 0.10436 0.01709  0.01120  -0.01328 80  VAL A C   
833  O  O   . VAL A 57  ? 0.17276 0.19570 0.10940 0.03256  0.02158  0.00216  80  VAL A O   
834  C  CB  . VAL A 57  ? 0.17443 0.17081 0.14014 0.02361  0.00379  -0.00154 80  VAL A CB  
835  C  CG1 . VAL A 57  ? 0.18420 0.21225 0.15835 0.04634  0.01429  0.02282  80  VAL A CG1 
836  C  CG2 . VAL A 57  ? 0.18588 0.21097 0.14606 0.05291  0.00225  -0.00971 80  VAL A CG2 
846  N  N   . LEU A 58  ? 0.15386 0.19997 0.09697 0.02800  -0.00883 0.00156  81  LEU A N   
847  C  CA  . LEU A 58  ? 0.13205 0.19842 0.10122 0.02861  0.00101  -0.00458 81  LEU A CA  
848  C  C   . LEU A 58  ? 0.14366 0.19761 0.09858 0.03162  0.00369  -0.00660 81  LEU A C   
849  O  O   . LEU A 58  ? 0.16159 0.20708 0.10880 0.03144  0.02070  0.01009  81  LEU A O   
850  C  CB  . LEU A 58  ? 0.13225 0.19406 0.10460 0.01032  0.00575  -0.00115 81  LEU A CB  
851  C  CG  . LEU A 58  ? 0.13088 0.19817 0.11408 -0.00210 0.01291  -0.01519 81  LEU A CG  
852  C  CD1 . LEU A 58  ? 0.15238 0.20065 0.12574 -0.01228 0.01008  -0.03258 81  LEU A CD1 
853  C  CD2 . LEU A 58  ? 0.16295 0.22849 0.12378 0.00913  0.01570  -0.00504 81  LEU A CD2 
865  N  N   . LYS A 59  ? 0.14329 0.18842 0.10930 0.03718  0.00304  0.00470  82  LYS A N   
866  C  CA  . LYS A 59  ? 0.15194 0.20516 0.11278 0.03440  -0.00752 -0.00322 82  LYS A CA  
867  C  C   . LYS A 59  ? 0.19144 0.22203 0.11068 0.05403  0.01082  0.00418  82  LYS A C   
868  O  O   . LYS A 59  ? 0.23489 0.26221 0.10404 0.06679  0.01644  0.01380  82  LYS A O   
869  C  CB  . LYS A 59  ? 0.16721 0.25187 0.12654 0.07521  -0.03720 -0.01401 82  LYS A CB  
870  C  CG  . LYS A 59  ? 0.22385 0.29265 0.15612 0.08305  -0.03008 -0.00393 82  LYS A CG  
871  C  CD  . LYS A 59  ? 0.33033 0.36663 0.18575 0.06674  -0.03871 0.03496  82  LYS A CD  
872  C  CE  . LYS A 59  ? 0.40911 0.40291 0.20480 0.05998  -0.04573 0.06841  82  LYS A CE  
873  N  NZ  . LYS A 59  ? 0.48413 0.42512 0.21023 -0.01377 -0.06882 0.07366  82  LYS A NZ  
887  N  N   . LYS A 60  ? 0.22516 0.22865 0.11412 0.05362  0.00003  -0.00682 83  LYS A N   
888  C  CA  . LYS A 60  ? 0.26668 0.26807 0.12063 0.08487  -0.00778 -0.02057 83  LYS A CA  
889  C  C   . LYS A 60  ? 0.26139 0.25093 0.11225 0.08075  0.00015  -0.02880 83  LYS A C   
890  O  O   . LYS A 60  ? 0.32313 0.26703 0.10694 0.08580  0.01542  -0.03046 83  LYS A O   
891  C  CB  . LYS A 60  ? 0.38088 0.28750 0.14699 0.07348  0.00551  -0.03254 83  LYS A CB  
892  C  CG  . LYS A 60  ? 0.50439 0.40094 0.18261 0.07187  0.00499  -0.03249 83  LYS A CG  
893  C  CD  . LYS A 60  ? 0.61084 0.49651 0.20022 0.06956  0.01894  -0.03038 83  LYS A CD  
894  C  CE  . LYS A 60  ? 0.68395 0.55215 0.20984 0.07180  0.03784  -0.04273 83  LYS A CE  
895  N  NZ  . LYS A 60  ? 0.71239 0.60104 0.22463 0.05025  0.04367  -0.02821 83  LYS A NZ  
909  N  N   . SER A 61  ? 0.21293 0.26234 0.11807 0.05809  0.01044  -0.02862 84  SER A N   
910  C  CA  . SER A 61  ? 0.23841 0.27549 0.13990 0.06276  0.04185  -0.02169 84  SER A CA  
911  C  C   . SER A 61  ? 0.25841 0.27503 0.15814 0.07320  0.07338  0.00410  84  SER A C   
912  O  O   . SER A 61  ? 0.25984 0.31323 0.15276 0.06070  0.08342  0.01477  84  SER A O   
913  C  CB  . SER A 61  ? 0.19514 0.29461 0.14920 0.06958  0.04138  -0.03021 84  SER A CB  
914  O  OG  . SER A 61  ? 0.18734 0.33236 0.16042 0.03619  0.04469  -0.04737 84  SER A OG  
920  N  N   A GLU A 62  ? 0.25390 0.26979 0.16825 0.07688  0.07071  0.02493  85  GLU A N   
921  N  N   B GLU A 62  ? 0.28678 0.28999 0.16965 0.07333  0.06764  0.01102  85  GLU A N   
922  C  CA  A GLU A 62  ? 0.27159 0.28152 0.17829 0.08647  0.08622  0.02933  85  GLU A CA  
923  C  CA  B GLU A 62  ? 0.32519 0.31435 0.18080 0.07810  0.07133  0.00857  85  GLU A CA  
924  C  C   A GLU A 62  ? 0.34280 0.31432 0.19099 0.11948  0.07843  0.04068  85  GLU A C   
925  C  C   B GLU A 62  ? 0.36187 0.33303 0.18852 0.10077  0.07251  0.02380  85  GLU A C   
926  O  O   A GLU A 62  ? 0.39246 0.32606 0.20600 0.07716  0.08733  0.05370  85  GLU A O   
927  O  O   B GLU A 62  ? 0.38769 0.34139 0.19750 0.08190  0.07764  0.02910  85  GLU A O   
928  C  CB  A GLU A 62  ? 0.26045 0.26818 0.17385 0.10129  0.07741  0.02497  85  GLU A CB  
929  C  CB  B GLU A 62  ? 0.34341 0.32428 0.18283 0.07396  0.06233  -0.00932 85  GLU A CB  
930  C  CG  A GLU A 62  ? 0.22727 0.26137 0.16325 0.08147  0.06472  0.03345  85  GLU A CG  
931  C  CG  B GLU A 62  ? 0.35155 0.33596 0.18179 0.05611  0.05098  -0.02601 85  GLU A CG  
932  C  CD  A GLU A 62  ? 0.20665 0.25565 0.16753 0.03470  0.05153  0.04317  85  GLU A CD  
933  C  CD  B GLU A 62  ? 0.35586 0.35798 0.18378 0.05719  0.04589  -0.04593 85  GLU A CD  
934  O  OE1 A GLU A 62  ? 0.20482 0.25348 0.17044 0.04279  0.03979  0.07119  85  GLU A OE1 
935  O  OE1 B GLU A 62  ? 0.33379 0.37558 0.17839 0.08848  0.04966  -0.04608 85  GLU A OE1 
936  O  OE2 A GLU A 62  ? 0.20530 0.22285 0.17301 -0.00051 0.04367  0.00575  85  GLU A OE2 
937  O  OE2 B GLU A 62  ? 0.37748 0.34684 0.18801 0.03648  0.04363  -0.07073 85  GLU A OE2 
950  N  N   . SER A 63  ? 0.37204 0.33918 0.18495 0.11173  0.07420  0.02919  86  SER A N   
951  C  CA  . SER A 63  ? 0.44215 0.42879 0.18597 0.11530  0.06216  0.02942  86  SER A CA  
952  C  C   . SER A 63  ? 0.45918 0.42477 0.18218 0.16522  0.05904  0.01973  86  SER A C   
953  O  O   . SER A 63  ? 0.49225 0.42635 0.16946 0.16328  0.05207  -0.00240 86  SER A O   
954  C  CB  . SER A 63  ? 0.49256 0.50502 0.21120 0.08724  0.03647  0.03109  86  SER A CB  
955  O  OG  . SER A 63  ? 0.51922 0.55631 0.22711 0.07604  0.02876  0.02895  86  SER A OG  
961  N  N   . GLU A 64  ? 0.45729 0.41767 0.20629 0.20225  0.05327  0.04419  87  GLU A N   
962  C  CA  . GLU A 64  ? 0.47250 0.44019 0.24352 0.19292  0.04035  0.05212  87  GLU A CA  
963  C  C   . GLU A 64  ? 0.44345 0.40599 0.26534 0.13166  0.05182  0.04697  87  GLU A C   
964  O  O   . GLU A 64  ? 0.38831 0.34016 0.25190 0.11343  0.05810  0.03130  87  GLU A O   
965  C  CB  . GLU A 64  ? 0.55556 0.54542 0.26919 0.14752  0.02008  0.05577  87  GLU A CB  
966  C  CG  . GLU A 64  ? 0.65531 0.64401 0.29248 0.10538  0.00986  0.06287  87  GLU A CG  
967  C  CD  . GLU A 64  ? 0.72802 0.71792 0.31306 0.07820  0.00055  0.06588  87  GLU A CD  
968  O  OE1 . GLU A 64  ? 0.76085 0.73036 0.31179 0.06697  -0.01146 0.08390  87  GLU A OE1 
969  O  OE2 . GLU A 64  ? 0.75008 0.74969 0.32819 0.06143  0.00748  0.04918  87  GLU A OE2 
976  N  N   . PRO A 65  ? 0.47376 0.45897 0.29467 0.05872  0.05391  0.07717  88  PRO A N   
977  C  CA  . PRO A 65  ? 0.50778 0.48378 0.30704 0.01518  0.04938  0.09591  88  PRO A CA  
978  C  C   . PRO A 65  ? 0.52080 0.48134 0.29679 -0.00249 0.04800  0.09955  88  PRO A C   
979  O  O   . PRO A 65  ? 0.57062 0.53176 0.31091 -0.01730 0.02137  0.07487  88  PRO A O   
980  C  CB  . PRO A 65  ? 0.52485 0.50896 0.32152 -0.02171 0.04851  0.10297  88  PRO A CB  
981  C  CG  . PRO A 65  ? 0.52646 0.52748 0.32651 -0.02641 0.04362  0.09880  88  PRO A CG  
982  C  CD  . PRO A 65  ? 0.50757 0.51416 0.31709 0.00638  0.04365  0.08641  88  PRO A CD  
990  N  N   . ASN A 66  ? 0.44326 0.40075 0.26864 0.01707  0.08695  0.10747  89  ASN A N   
991  C  CA  . ASN A 66  ? 0.40614 0.40145 0.24273 0.03457  0.09606  0.07112  89  ASN A CA  
992  C  C   . ASN A 66  ? 0.28813 0.32515 0.21572 0.03547  0.07687  0.03695  89  ASN A C   
993  O  O   . ASN A 66  ? 0.25219 0.34961 0.21300 0.04488  0.06280  0.02811  89  ASN A O   
994  C  CB  . ASN A 66  ? 0.51376 0.47442 0.25006 0.03727  0.11486  0.06082  89  ASN A CB  
995  C  CG  . ASN A 66  ? 0.63595 0.55013 0.26337 0.01055  0.11213  0.04738  89  ASN A CG  
996  O  OD1 . ASN A 66  ? 0.66359 0.57057 0.26185 -0.01430 0.13582  0.05445  89  ASN A OD1 
997  N  ND2 . ASN A 66  ? 0.68424 0.57725 0.27533 0.01353  0.09591  0.03742  89  ASN A ND2 
1004 N  N   . LEU A 67  ? 0.23565 0.29099 0.20141 0.05394  0.04831  0.02188  90  LEU A N   
1005 C  CA  . LEU A 67  ? 0.22136 0.23805 0.20440 0.03093  0.03168  0.00765  90  LEU A CA  
1006 C  C   . LEU A 67  ? 0.22506 0.22378 0.20295 0.01806  0.02627  0.02002  90  LEU A C   
1007 O  O   . LEU A 67  ? 0.20722 0.22954 0.20528 0.01538  0.03546  0.02250  90  LEU A O   
1008 C  CB  . LEU A 67  ? 0.20620 0.25305 0.21269 0.03096  0.01351  0.01844  90  LEU A CB  
1009 C  CG  . LEU A 67  ? 0.21089 0.25749 0.22732 0.00209  0.00433  0.00309  90  LEU A CG  
1010 C  CD1 . LEU A 67  ? 0.21804 0.24107 0.22895 -0.00343 -0.00997 -0.01845 90  LEU A CD1 
1011 C  CD2 . LEU A 67  ? 0.23384 0.27745 0.23215 0.00500  0.00924  0.01844  90  LEU A CD2 
1023 N  N   . LEU A 68  ? 0.21131 0.20869 0.19426 0.02433  0.04890  0.01501  91  LEU A N   
1024 C  CA  . LEU A 68  ? 0.19419 0.24247 0.19752 0.00110  0.05696  0.01546  91  LEU A CA  
1025 C  C   . LEU A 68  ? 0.17462 0.24627 0.18197 0.00932  0.06609  0.01923  91  LEU A C   
1026 O  O   . LEU A 68  ? 0.18407 0.23277 0.16796 0.00927  0.05893  0.02047  91  LEU A O   
1027 C  CB  . LEU A 68  ? 0.20454 0.25645 0.22098 0.04678  0.05762  0.00242  91  LEU A CB  
1028 C  CG  . LEU A 68  ? 0.25193 0.31924 0.24376 0.05783  0.06452  -0.01604 91  LEU A CG  
1029 C  CD1 . LEU A 68  ? 0.31747 0.34810 0.26384 0.08423  0.05001  -0.03230 91  LEU A CD1 
1030 C  CD2 . LEU A 68  ? 0.25954 0.35761 0.25501 0.07981  0.06661  -0.00570 91  LEU A CD2 
1042 N  N   . ASN A 69  ? 0.17985 0.21914 0.19125 0.02547  0.07643  0.02906  92  ASN A N   
1043 C  CA  . ASN A 69  ? 0.16690 0.21901 0.20992 0.01473  0.07775  0.03517  92  ASN A CA  
1044 C  C   . ASN A 69  ? 0.17585 0.22669 0.21436 0.00975  0.06346  0.01399  92  ASN A C   
1045 O  O   . ASN A 69  ? 0.16755 0.22735 0.23436 0.01830  0.05658  0.02248  92  ASN A O   
1046 C  CB  . ASN A 69  ? 0.20839 0.23199 0.24460 0.00951  0.08376  0.03848  92  ASN A CB  
1047 C  CG  . ASN A 69  ? 0.26442 0.27238 0.27475 0.00373  0.10056  0.02833  92  ASN A CG  
1048 O  OD1 . ASN A 69  ? 0.27300 0.29694 0.29472 -0.01056 0.07419  0.00953  92  ASN A OD1 
1049 N  ND2 . ASN A 69  ? 0.32440 0.29832 0.28836 -0.00246 0.11770  0.02752  92  ASN A ND2 
1056 N  N   . GLN A 70  ? 0.16453 0.24790 0.19379 -0.01255 0.07322  0.00562  93  GLN A N   
1057 C  CA  . GLN A 70  ? 0.20815 0.23094 0.19728 -0.00023 0.04234  0.00366  93  GLN A CA  
1058 C  C   . GLN A 70  ? 0.16094 0.22595 0.18071 -0.01721 0.06270  0.00001  93  GLN A C   
1059 O  O   . GLN A 70  ? 0.17145 0.24655 0.18176 -0.01790 0.05493  -0.02574 93  GLN A O   
1060 C  CB  . GLN A 70  ? 0.24475 0.24937 0.21597 -0.02513 0.00818  -0.00497 93  GLN A CB  
1061 C  CG  . GLN A 70  ? 0.34818 0.33901 0.24451 -0.04587 0.00029  -0.00596 93  GLN A CG  
1062 C  CD  . GLN A 70  ? 0.44287 0.39256 0.26369 -0.06359 0.00644  -0.01406 93  GLN A CD  
1063 O  OE1 . GLN A 70  ? 0.49732 0.40119 0.28457 -0.05112 0.00077  -0.03454 93  GLN A OE1 
1064 N  NE2 . GLN A 70  ? 0.45779 0.42797 0.26833 -0.05314 0.02635  -0.01477 93  GLN A NE2 
1073 N  N   . ARG A 71  ? 0.21034 0.22575 0.18863 -0.02507 0.06420  0.01121  94  ARG A N   
1074 C  CA  . ARG A 71  ? 0.21116 0.21181 0.19844 -0.03212 0.07626  -0.00095 94  ARG A CA  
1075 C  C   . ARG A 71  ? 0.16606 0.23236 0.18405 -0.00260 0.05357  -0.01904 94  ARG A C   
1076 O  O   . ARG A 71  ? 0.22374 0.27304 0.18477 -0.03785 0.06070  -0.02049 94  ARG A O   
1077 C  CB  . ARG A 71  ? 0.17720 0.24368 0.23493 -0.01084 0.05758  0.02462  94  ARG A CB  
1078 C  CG  . ARG A 71  ? 0.18529 0.23390 0.25930 0.03629  0.04650  0.02198  94  ARG A CG  
1079 C  CD  . ARG A 71  ? 0.19389 0.22574 0.26973 0.00292  0.04294  0.00786  94  ARG A CD  
1080 N  NE  . ARG A 71  ? 0.15714 0.18155 0.28122 0.01879  0.04376  0.00400  94  ARG A NE  
1081 C  CZ  . ARG A 71  ? 0.13153 0.18697 0.27756 -0.00490 0.02592  0.03499  94  ARG A CZ  
1082 N  NH1 . ARG A 71  ? 0.15250 0.19403 0.28318 -0.01608 0.03056  0.03672  94  ARG A NH1 
1083 N  NH2 . ARG A 71  ? 0.14230 0.19331 0.27675 -0.00131 0.02280  0.04718  94  ARG A NH2 
1097 N  N   . VAL A 72  ? 0.14774 0.23185 0.18063 0.00564  0.05170  -0.01403 95  VAL A N   
1098 C  CA  . VAL A 72  ? 0.12588 0.23516 0.18889 0.03108  0.03774  -0.01157 95  VAL A CA  
1099 C  C   . VAL A 72  ? 0.09328 0.21185 0.19336 0.00523  0.04063  -0.01746 95  VAL A C   
1100 O  O   . VAL A 72  ? 0.11710 0.20790 0.19612 -0.00591 0.03254  -0.01776 95  VAL A O   
1101 C  CB  . VAL A 72  ? 0.15085 0.25092 0.19249 0.02614  0.03302  -0.01033 95  VAL A CB  
1102 C  CG1 . VAL A 72  ? 0.17030 0.26630 0.19739 0.00939  0.06232  -0.01008 95  VAL A CG1 
1103 C  CG2 . VAL A 72  ? 0.16251 0.27075 0.19901 0.01610  0.03632  -0.02278 95  VAL A CG2 
1113 N  N   . GLU A 73  ? 0.15738 0.22981 0.20518 -0.01504 0.06366  -0.03280 96  GLU A N   
1114 C  CA  . GLU A 73  ? 0.18421 0.20589 0.21636 -0.02798 0.07628  -0.03457 96  GLU A CA  
1115 C  C   . GLU A 73  ? 0.13247 0.20707 0.20686 -0.02351 0.05959  -0.02154 96  GLU A C   
1116 O  O   . GLU A 73  ? 0.14240 0.25640 0.20108 -0.03548 0.06475  -0.02010 96  GLU A O   
1117 C  CB  . GLU A 73  ? 0.25091 0.22265 0.24476 -0.03156 0.08494  -0.04123 96  GLU A CB  
1118 C  CG  . GLU A 73  ? 0.35043 0.31364 0.27394 -0.03701 0.08811  -0.02106 96  GLU A CG  
1119 C  CD  . GLU A 73  ? 0.40516 0.35817 0.29042 -0.02582 0.10964  -0.00720 96  GLU A CD  
1120 O  OE1 . GLU A 73  ? 0.41603 0.33572 0.30570 -0.02474 0.14810  -0.01764 96  GLU A OE1 
1121 O  OE2 . GLU A 73  ? 0.43225 0.34699 0.29464 -0.04623 0.06843  0.01958  96  GLU A OE2 
1128 N  N   . ILE A 74  ? 0.13891 0.17650 0.21307 0.00116  0.05829  -0.01866 97  ILE A N   
1129 C  CA  . ILE A 74  ? 0.14259 0.18162 0.22065 0.00574  0.02922  -0.00854 97  ILE A CA  
1130 C  C   . ILE A 74  ? 0.18237 0.18824 0.23630 0.02674  0.04347  0.00468  97  ILE A C   
1131 O  O   . ILE A 74  ? 0.19539 0.19973 0.25898 0.02636  0.00754  -0.00478 97  ILE A O   
1132 C  CB  . ILE A 74  ? 0.13961 0.20393 0.21877 -0.00614 0.01856  -0.02214 97  ILE A CB  
1133 C  CG1 . ILE A 74  ? 0.15482 0.21155 0.23027 0.01090  0.00763  -0.02174 97  ILE A CG1 
1134 C  CG2 . ILE A 74  ? 0.17803 0.20826 0.21484 0.02383  0.02668  -0.02007 97  ILE A CG2 
1135 C  CD1 . ILE A 74  ? 0.16366 0.21393 0.23009 -0.00320 -0.02503 -0.02466 97  ILE A CD1 
1147 N  N   . LYS A 75  ? 0.19526 0.17273 0.23470 0.00402  0.06743  0.00939  98  LYS A N   
1148 C  CA  . LYS A 75  ? 0.23967 0.18437 0.23664 0.00112  0.07598  0.01594  98  LYS A CA  
1149 C  C   . LYS A 75  ? 0.20253 0.17305 0.23246 -0.00929 0.05752  0.01007  98  LYS A C   
1150 O  O   . LYS A 75  ? 0.17478 0.16602 0.21598 0.00339  0.03982  -0.00274 98  LYS A O   
1151 C  CB  . LYS A 75  ? 0.32931 0.21203 0.23729 -0.03559 0.09277  0.00655  98  LYS A CB  
1152 C  CG  . LYS A 75  ? 0.37435 0.26716 0.24335 -0.06548 0.09627  -0.00673 98  LYS A CG  
1153 C  CD  . LYS A 75  ? 0.41074 0.34758 0.25482 -0.04282 0.08757  -0.01916 98  LYS A CD  
1154 C  CE  . LYS A 75  ? 0.45946 0.38120 0.26401 -0.02724 0.06641  -0.02836 98  LYS A CE  
1155 N  NZ  . LYS A 75  ? 0.48216 0.39165 0.26473 0.01555  0.05676  -0.04644 98  LYS A NZ  
1169 N  N   . LYS A 76  ? 0.23790 0.18221 0.24294 0.02661  0.03385  0.01818  99  LYS A N   
1170 C  CA  . LYS A 76  ? 0.25883 0.18229 0.24416 0.02392  0.01830  0.01660  99  LYS A CA  
1171 C  C   . LYS A 76  ? 0.24335 0.17518 0.21670 0.00100  0.01999  0.02811  99  LYS A C   
1172 O  O   . LYS A 76  ? 0.25255 0.19640 0.19493 -0.03284 0.03459  0.01843  99  LYS A O   
1173 C  CB  . LYS A 76  ? 0.35424 0.24059 0.26608 0.02227  -0.01078 0.01346  99  LYS A CB  
1174 C  CG  . LYS A 76  ? 0.51322 0.36852 0.28139 0.00814  -0.02443 0.03123  99  LYS A CG  
1175 C  CD  . LYS A 76  ? 0.62071 0.49315 0.29518 -0.02416 -0.03046 0.03832  99  LYS A CD  
1176 C  CE  . LYS A 76  ? 0.69732 0.58904 0.30664 -0.04286 -0.03096 0.02734  99  LYS A CE  
1177 N  NZ  . LYS A 76  ? 0.74304 0.63995 0.31128 -0.04484 -0.03504 0.02016  99  LYS A NZ  
1191 N  N   . SER A 77  ? 0.24602 0.17183 0.20374 -0.02014 0.02583  0.01665  100 SER A N   
1192 C  CA  . SER A 77  ? 0.25421 0.20032 0.20125 -0.05351 0.03525  -0.01301 100 SER A CA  
1193 C  C   . SER A 77  ? 0.20708 0.20883 0.19224 -0.04116 0.04256  -0.02483 100 SER A C   
1194 O  O   . SER A 77  ? 0.20446 0.22373 0.20817 -0.05700 0.03466  -0.02675 100 SER A O   
1195 C  CB  . SER A 77  ? 0.27449 0.22867 0.21277 -0.05499 0.04384  -0.04494 100 SER A CB  
1196 O  OG  . SER A 77  ? 0.31322 0.24803 0.22349 -0.03820 0.04707  -0.05026 100 SER A OG  
1202 N  N   . ASP A 78  ? 0.17510 0.17590 0.17338 -0.03045 0.05364  -0.02255 101 ASP A N   
1203 C  CA  . ASP A 78  ? 0.15408 0.19440 0.16822 -0.01202 0.03141  -0.01827 101 ASP A CA  
1204 C  C   . ASP A 78  ? 0.16523 0.18954 0.16107 -0.00236 0.01872  -0.00350 101 ASP A C   
1205 O  O   . ASP A 78  ? 0.16085 0.18960 0.16928 0.00024  0.03102  0.00080  101 ASP A O   
1206 C  CB  . ASP A 78  ? 0.15365 0.18845 0.16235 -0.00303 0.03129  -0.02754 101 ASP A CB  
1207 C  CG  . ASP A 78  ? 0.18447 0.20297 0.16583 -0.00009 0.03567  -0.01994 101 ASP A CG  
1208 O  OD1 . ASP A 78  ? 0.17601 0.25979 0.16862 0.00859  0.01036  -0.02293 101 ASP A OD1 
1209 O  OD2 . ASP A 78  ? 0.19506 0.24262 0.15972 -0.04510 0.05602  -0.02771 101 ASP A OD2 
1214 N  N   . LEU A 79  ? 0.17146 0.18083 0.16325 -0.00816 0.01624  -0.01262 102 LEU A N   
1215 C  CA  . LEU A 79  ? 0.18096 0.14517 0.17284 -0.01794 0.03143  -0.00345 102 LEU A CA  
1216 C  C   . LEU A 79  ? 0.22309 0.15746 0.18991 -0.05670 0.03078  -0.00512 102 LEU A C   
1217 O  O   . LEU A 79  ? 0.27365 0.19664 0.22733 -0.06871 0.07442  -0.02919 102 LEU A O   
1218 C  CB  . LEU A 79  ? 0.19615 0.15695 0.17580 0.00243  0.01307  0.00988  102 LEU A CB  
1219 C  CG  . LEU A 79  ? 0.20316 0.19423 0.19821 0.01375  0.00378  0.00855  102 LEU A CG  
1220 C  CD1 . LEU A 79  ? 0.22463 0.25234 0.21381 0.05527  -0.00109 0.01941  102 LEU A CD1 
1221 C  CD2 . LEU A 79  ? 0.22980 0.19150 0.21885 -0.03506 -0.00063 -0.00072 102 LEU A CD2 
1233 N  N   . VAL A 80  ? 0.21319 0.17299 0.17306 -0.04457 0.05138  0.00487  103 VAL A N   
1234 C  CA  . VAL A 80  ? 0.20610 0.21317 0.18222 -0.04332 0.05153  -0.00826 103 VAL A CA  
1235 C  C   . VAL A 80  ? 0.24583 0.24356 0.17878 -0.02457 0.03462  -0.00076 103 VAL A C   
1236 O  O   . VAL A 80  ? 0.26089 0.28563 0.18705 -0.03329 0.03889  0.00422  103 VAL A O   
1237 C  CB  . VAL A 80  ? 0.19557 0.22256 0.19618 -0.01594 0.05521  -0.01899 103 VAL A CB  
1238 C  CG1 . VAL A 80  ? 0.16457 0.24252 0.20368 -0.00929 0.04300  -0.00564 103 VAL A CG1 
1239 C  CG2 . VAL A 80  ? 0.21037 0.19436 0.20537 -0.01272 0.04661  -0.01773 103 VAL A CG2 
1249 N  N   . ASN A 81  ? 0.25630 0.23843 0.16969 -0.02920 0.02622  0.02236  104 ASN A N   
1250 C  CA  . ASN A 81  ? 0.25869 0.26368 0.16484 -0.02445 0.02180  0.00260  104 ASN A CA  
1251 C  C   . ASN A 81  ? 0.26208 0.29223 0.15591 -0.02430 0.02326  -0.01036 104 ASN A C   
1252 O  O   . ASN A 81  ? 0.29129 0.34542 0.15242 -0.03972 0.03830  -0.00431 104 ASN A O   
1253 C  CB  . ASN A 81  ? 0.25190 0.30893 0.17442 0.00227  0.03081  -0.00464 104 ASN A CB  
1254 C  CG  . ASN A 81  ? 0.24846 0.33109 0.18122 0.03843  0.03918  -0.01465 104 ASN A CG  
1255 O  OD1 . ASN A 81  ? 0.20472 0.29939 0.17964 0.00028  0.02850  -0.00524 104 ASN A OD1 
1256 N  ND2 . ASN A 81  ? 0.29046 0.36000 0.19722 0.05517  0.04326  -0.01947 104 ASN A ND2 
1263 N  N   . TYR A 82  ? 0.22934 0.24454 0.14462 -0.01395 0.03532  -0.01280 105 TYR A N   
1264 C  CA  . TYR A 82  ? 0.19251 0.23934 0.13339 0.01578  0.00727  -0.00035 105 TYR A CA  
1265 C  C   . TYR A 82  ? 0.18679 0.22379 0.12462 0.01239  0.01278  0.01614  105 TYR A C   
1266 O  O   . TYR A 82  ? 0.19448 0.23882 0.12977 0.00220  -0.01494 0.03085  105 TYR A O   
1267 C  CB  . TYR A 82  ? 0.22676 0.22364 0.14818 -0.00285 0.00661  0.01163  105 TYR A CB  
1268 C  CG  . TYR A 82  ? 0.22759 0.21661 0.16047 -0.00495 -0.02158 -0.01167 105 TYR A CG  
1269 C  CD1 . TYR A 82  ? 0.31081 0.30705 0.18130 -0.06430 -0.05010 -0.00726 105 TYR A CD1 
1270 C  CD2 . TYR A 82  ? 0.20164 0.19455 0.18001 0.02907  0.00519  -0.01549 105 TYR A CD2 
1271 C  CE1 . TYR A 82  ? 0.34605 0.33776 0.20470 -0.09349 -0.05590 -0.01581 105 TYR A CE1 
1272 C  CE2 . TYR A 82  ? 0.24939 0.22833 0.20413 0.01187  0.01201  -0.01591 105 TYR A CE2 
1273 C  CZ  . TYR A 82  ? 0.33980 0.31561 0.22430 -0.07092 -0.04154 -0.02947 105 TYR A CZ  
1274 O  OH  . TYR A 82  ? 0.41552 0.38576 0.24913 -0.09946 -0.07111 -0.04197 105 TYR A OH  
1284 N  N   . ASN A 83  ? 0.19377 0.20908 0.13972 0.01815  0.00502  0.00353  106 ASN A N   
1285 C  CA  . ASN A 83  ? 0.21039 0.21897 0.15776 -0.00448 0.00496  -0.00846 106 ASN A CA  
1286 C  C   . ASN A 83  ? 0.17808 0.20976 0.16299 -0.00050 -0.01237 -0.01125 106 ASN A C   
1287 O  O   . ASN A 83  ? 0.19396 0.18946 0.17261 0.02614  0.00813  -0.01359 106 ASN A O   
1288 C  CB  . ASN A 83  ? 0.25573 0.24640 0.17154 -0.02874 0.01841  -0.02684 106 ASN A CB  
1289 C  CG  . ASN A 83  ? 0.25242 0.24656 0.17443 -0.03811 0.02737  -0.01246 106 ASN A CG  
1290 O  OD1 . ASN A 83  ? 0.23290 0.26148 0.17187 -0.02983 0.02068  0.00077  106 ASN A OD1 
1291 N  ND2 . ASN A 83  ? 0.26369 0.25343 0.18205 -0.02213 0.01763  -0.01690 106 ASN A ND2 
1298 N  N   . PRO A 84  ? 0.14759 0.21509 0.16512 0.00952  -0.01701 -0.00988 107 PRO A N   
1299 C  CA  . PRO A 84  ? 0.17486 0.24985 0.17595 0.01090  -0.02794 -0.00916 107 PRO A CA  
1300 C  C   . PRO A 84  ? 0.15802 0.23188 0.18958 0.02353  -0.04575 -0.00400 107 PRO A C   
1301 O  O   . PRO A 84  ? 0.18837 0.29304 0.19147 0.01721  -0.03631 0.01197  107 PRO A O   
1302 C  CB  . PRO A 84  ? 0.21260 0.26154 0.18198 -0.01231 -0.02430 -0.03064 107 PRO A CB  
1303 C  CG  . PRO A 84  ? 0.21590 0.22837 0.18734 -0.00207 -0.01017 -0.03041 107 PRO A CG  
1304 C  CD  . PRO A 84  ? 0.16853 0.22039 0.17579 -0.00166 -0.01210 -0.02248 107 PRO A CD  
1312 N  N   . ILE A 85  ? 0.15534 0.20740 0.19299 0.03020  -0.04492 -0.01100 108 ILE A N   
1313 C  CA  . ILE A 85  ? 0.15441 0.23369 0.18672 0.03389  -0.03854 -0.00589 108 ILE A CA  
1314 C  C   . ILE A 85  ? 0.13087 0.23819 0.17730 0.02876  -0.02460 -0.02653 108 ILE A C   
1315 O  O   . ILE A 85  ? 0.15367 0.24467 0.19252 0.03567  -0.02496 -0.02160 108 ILE A O   
1316 C  CB  . ILE A 85  ? 0.15857 0.24014 0.19214 0.00426  -0.03096 0.00305  108 ILE A CB  
1317 C  CG1 . ILE A 85  ? 0.17709 0.24469 0.20713 -0.00563 -0.03082 -0.01001 108 ILE A CG1 
1318 C  CG2 . ILE A 85  ? 0.16254 0.27408 0.19498 0.01518  -0.02229 0.02139  108 ILE A CG2 
1319 C  CD1 . ILE A 85  ? 0.20925 0.27534 0.21709 -0.01858 -0.02101 -0.00071 108 ILE A CD1 
1331 N  N   . ALA A 86  ? 0.12623 0.22914 0.17842 0.02484  -0.01730 -0.03637 109 ALA A N   
1332 C  CA  . ALA A 86  ? 0.15457 0.22363 0.18804 0.01925  -0.00671 -0.04117 109 ALA A CA  
1333 C  C   . ALA A 86  ? 0.15581 0.23720 0.20248 0.03199  -0.00106 -0.03584 109 ALA A C   
1334 O  O   . ALA A 86  ? 0.18419 0.22617 0.20801 0.03837  -0.00454 -0.04493 109 ALA A O   
1335 C  CB  . ALA A 86  ? 0.14477 0.24396 0.18413 0.00580  -0.04098 -0.04904 109 ALA A CB  
1341 N  N   . GLU A 87  ? 0.19966 0.20654 0.21528 0.03844  -0.00966 -0.02733 110 GLU A N   
1342 C  CA  . GLU A 87  ? 0.25308 0.23236 0.25576 0.05295  -0.00989 -0.01712 110 GLU A CA  
1343 C  C   . GLU A 87  ? 0.24919 0.25961 0.28354 0.08207  -0.01669 -0.01245 110 GLU A C   
1344 O  O   . GLU A 87  ? 0.24549 0.28922 0.29587 0.09885  -0.01313 -0.00820 110 GLU A O   
1345 C  CB  . GLU A 87  ? 0.33085 0.25262 0.26995 0.08415  -0.01220 0.00081  110 GLU A CB  
1346 C  CG  . GLU A 87  ? 0.42866 0.31638 0.27921 0.06453  -0.01884 0.00062  110 GLU A CG  
1347 C  CD  . GLU A 87  ? 0.51861 0.37326 0.29642 0.04256  -0.00675 -0.00404 110 GLU A CD  
1348 O  OE1 . GLU A 87  ? 0.55682 0.37723 0.31120 0.01705  0.03025  0.00508  110 GLU A OE1 
1349 O  OE2 . GLU A 87  ? 0.54262 0.40545 0.28985 0.05771  -0.02614 -0.00951 110 GLU A OE2 
1356 N  N   . LYS A 88  ? 0.20613 0.25784 0.29912 0.07826  -0.04313 -0.01806 111 LYS A N   
1357 C  CA  . LYS A 88  ? 0.16771 0.29572 0.31434 0.05563  -0.06233 -0.03064 111 LYS A CA  
1358 C  C   . LYS A 88  ? 0.15307 0.29803 0.30500 0.07326  -0.04356 -0.01843 111 LYS A C   
1359 O  O   . LYS A 88  ? 0.15733 0.38804 0.31048 0.06249  -0.04130 -0.02758 111 LYS A O   
1360 C  CB  . LYS A 88  ? 0.21872 0.37359 0.33723 0.04668  -0.08238 -0.07604 111 LYS A CB  
1361 C  CG  . LYS A 88  ? 0.30924 0.47214 0.36143 0.04223  -0.08249 -0.10164 111 LYS A CG  
1362 C  CD  . LYS A 88  ? 0.41235 0.55525 0.38442 0.02920  -0.08011 -0.11617 111 LYS A CD  
1363 C  CE  . LYS A 88  ? 0.50387 0.61498 0.42108 0.01514  -0.07659 -0.12092 111 LYS A CE  
1364 N  NZ  . LYS A 88  ? 0.54759 0.64500 0.44984 0.01298  -0.06996 -0.11731 111 LYS A NZ  
1378 N  N   . HIS A 89  ? 0.16253 0.23920 0.28639 0.04563  -0.00793 -0.00412 112 HIS A N   
1379 C  CA  . HIS A 89  ? 0.17356 0.22831 0.27785 0.04192  0.01471  -0.00702 112 HIS A CA  
1380 C  C   . HIS A 89  ? 0.16161 0.21162 0.26428 0.04491  0.02361  -0.00245 112 HIS A C   
1381 O  O   . HIS A 89  ? 0.17606 0.21579 0.25522 0.02750  0.03005  0.01078  112 HIS A O   
1382 C  CB  . HIS A 89  ? 0.17663 0.23346 0.28725 0.04322  0.02941  -0.01532 112 HIS A CB  
1383 C  CG  . HIS A 89  ? 0.18608 0.24997 0.30310 0.02457  0.03769  -0.02602 112 HIS A CG  
1384 N  ND1 . HIS A 89  ? 0.19762 0.26853 0.30990 0.02051  0.02825  -0.02592 112 HIS A ND1 
1385 C  CD2 . HIS A 89  ? 0.19094 0.25252 0.31450 0.03589  0.03295  -0.05017 112 HIS A CD2 
1386 C  CE1 . HIS A 89  ? 0.19680 0.24368 0.31635 -0.00977 0.04095  -0.04631 112 HIS A CE1 
1387 N  NE2 . HIS A 89  ? 0.19735 0.25453 0.32022 0.00968  0.03430  -0.06489 112 HIS A NE2 
1395 N  N   . VAL A 90  ? 0.18775 0.23259 0.26384 0.02872  0.02754  -0.00267 113 VAL A N   
1396 C  CA  . VAL A 90  ? 0.18241 0.23802 0.26592 0.03834  0.04970  -0.00712 113 VAL A CA  
1397 C  C   . VAL A 90  ? 0.18532 0.22117 0.27405 0.05323  0.04972  -0.00062 113 VAL A C   
1398 O  O   . VAL A 90  ? 0.20334 0.26443 0.27977 0.06236  0.04956  0.01133  113 VAL A O   
1399 C  CB  . VAL A 90  ? 0.23604 0.24128 0.26544 0.01351  0.07166  -0.01198 113 VAL A CB  
1400 C  CG1 . VAL A 90  ? 0.25591 0.25202 0.27065 0.04590  0.08863  -0.01297 113 VAL A CG1 
1401 C  CG2 . VAL A 90  ? 0.27610 0.26630 0.26908 0.00279  0.05632  -0.00649 113 VAL A CG2 
1411 N  N   . ASN A 91  ? 0.19837 0.18037 0.27634 0.02183  0.04315  0.00151  114 ASN A N   
1412 C  CA  . ASN A 91  ? 0.21048 0.17926 0.28566 0.02108  0.05959  -0.00173 114 ASN A CA  
1413 C  C   . ASN A 91  ? 0.20651 0.20042 0.27386 0.03223  0.07081  -0.00372 114 ASN A C   
1414 O  O   . ASN A 91  ? 0.24949 0.22188 0.27875 0.05223  0.08038  -0.01648 114 ASN A O   
1415 C  CB  . ASN A 91  ? 0.25370 0.21592 0.30513 0.04567  0.07051  0.01179  114 ASN A CB  
1416 C  CG  . ASN A 91  ? 0.32462 0.26684 0.32729 0.05541  0.06625  0.01356  114 ASN A CG  
1417 O  OD1 . ASN A 91  ? 0.34918 0.23540 0.34270 0.03754  0.06028  0.00809  114 ASN A OD1 
1418 N  ND2 . ASN A 91  ? 0.37311 0.33344 0.33182 0.08512  0.07642  0.03244  114 ASN A ND2 
1425 N  N   . GLY A 92  ? 0.16781 0.19135 0.25771 0.03596  0.05665  0.00731  115 GLY A N   
1426 C  CA  . GLY A 92  ? 0.14747 0.21899 0.24743 0.01019  0.04492  -0.00110 115 GLY A CA  
1427 C  C   . GLY A 92  ? 0.12479 0.21001 0.22682 0.01455  0.05642  -0.00565 115 GLY A C   
1428 O  O   . GLY A 92  ? 0.16054 0.20364 0.25288 0.01120  0.03936  0.00434  115 GLY A O   
1432 N  N   . THR A 93  ? 0.13384 0.20987 0.20752 -0.00305 0.04722  0.01807  116 THR A N   
1433 C  CA  . THR A 93  ? 0.13129 0.19386 0.19593 -0.00029 0.04463  -0.00118 116 THR A CA  
1434 C  C   . THR A 93  ? 0.11865 0.22101 0.18159 0.00997  0.03200  0.00333  116 THR A C   
1435 O  O   . THR A 93  ? 0.14407 0.23521 0.18829 0.00147  0.01705  0.00922  116 THR A O   
1436 C  CB  . THR A 93  ? 0.14236 0.20027 0.20392 0.00587  0.05074  -0.00195 116 THR A CB  
1437 O  OG1 . THR A 93  ? 0.12719 0.18473 0.19974 0.00111  0.05538  -0.01065 116 THR A OG1 
1438 C  CG2 . THR A 93  ? 0.16654 0.22649 0.21062 -0.01057 0.06443  -0.01915 116 THR A CG2 
1446 N  N   . MET A 94  ? 0.14350 0.22343 0.17234 0.00457  0.03160  -0.00571 117 MET A N   
1447 C  CA  . MET A 94  ? 0.14365 0.20158 0.16486 -0.00654 0.03864  -0.00947 117 MET A CA  
1448 C  C   . MET A 94  ? 0.14925 0.20719 0.16398 -0.00794 0.04625  0.00293  117 MET A C   
1449 O  O   . MET A 94  ? 0.17426 0.21055 0.14918 -0.00753 0.03715  0.01047  117 MET A O   
1450 C  CB  . MET A 94  ? 0.14529 0.22132 0.14717 -0.01712 0.02948  -0.00733 117 MET A CB  
1451 C  CG  . MET A 94  ? 0.17061 0.23718 0.15045 0.02657  0.01595  0.00652  117 MET A CG  
1452 S  SD  . MET A 94  ? 0.19150 0.20406 0.16181 0.02368  0.02736  0.00333  117 MET A SD  
1453 C  CE  . MET A 94  ? 0.21780 0.18670 0.16412 0.01727  0.01398  -0.00204 117 MET A CE  
1463 N  N   . SER A 95  ? 0.15797 0.18685 0.16258 -0.00436 0.05387  0.00488  118 SER A N   
1464 C  CA  . SER A 95  ? 0.15026 0.18900 0.16601 -0.00173 0.06288  -0.00198 118 SER A CA  
1465 C  C   . SER A 95  ? 0.13695 0.18583 0.14519 -0.01035 0.04592  -0.00672 118 SER A C   
1466 O  O   . SER A 95  ? 0.13454 0.20199 0.12966 -0.02122 0.03618  -0.00785 118 SER A O   
1467 C  CB  . SER A 95  ? 0.14215 0.19342 0.18320 0.00033  0.04775  -0.00312 118 SER A CB  
1468 O  OG  . SER A 95  ? 0.15318 0.21221 0.19418 -0.00172 0.05319  -0.00603 118 SER A OG  
1474 N  N   . LEU A 96  ? 0.13860 0.20769 0.15528 0.00101  0.04546  0.00636  119 LEU A N   
1475 C  CA  . LEU A 96  ? 0.13004 0.20942 0.14865 -0.00558 0.03874  0.00652  119 LEU A CA  
1476 C  C   . LEU A 96  ? 0.11863 0.18411 0.15232 -0.00487 0.03547  0.00503  119 LEU A C   
1477 O  O   . LEU A 96  ? 0.13368 0.18033 0.13919 -0.00220 0.03377  0.01242  119 LEU A O   
1478 C  CB  . LEU A 96  ? 0.13890 0.21597 0.15448 0.00418  0.02197  -0.01445 119 LEU A CB  
1479 C  CG  . LEU A 96  ? 0.14422 0.24510 0.18484 -0.03114 0.01449  -0.01384 119 LEU A CG  
1480 C  CD1 . LEU A 96  ? 0.17062 0.25115 0.20012 -0.01400 -0.01062 -0.02074 119 LEU A CD1 
1481 C  CD2 . LEU A 96  ? 0.14957 0.26373 0.19608 -0.03295 0.02094  -0.01472 119 LEU A CD2 
1493 N  N   . ALA A 97  ? 0.13511 0.17697 0.15869 -0.00907 0.04690  0.00130  120 ALA A N   
1494 C  CA  . ALA A 97  ? 0.14172 0.21042 0.16453 -0.02070 0.04212  0.01146  120 ALA A CA  
1495 C  C   . ALA A 97  ? 0.11727 0.17259 0.15963 -0.01073 0.02520  -0.00064 120 ALA A C   
1496 O  O   . ALA A 97  ? 0.13091 0.17207 0.16456 -0.00407 0.03342  -0.01136 120 ALA A O   
1497 C  CB  . ALA A 97  ? 0.18032 0.22549 0.17887 -0.02972 0.05229  0.00886  120 ALA A CB  
1503 N  N   . GLU A 98  ? 0.11605 0.17931 0.16185 0.00095  0.03030  -0.01228 121 GLU A N   
1504 C  CA  . GLU A 98  ? 0.11792 0.18585 0.17543 -0.00497 0.01585  -0.01019 121 GLU A CA  
1505 C  C   . GLU A 98  ? 0.10469 0.17047 0.15853 -0.00654 0.01373  -0.00317 121 GLU A C   
1506 O  O   . GLU A 98  ? 0.13230 0.18825 0.13525 0.01545  0.01750  -0.00486 121 GLU A O   
1507 C  CB  . GLU A 98  ? 0.10711 0.21790 0.19702 0.00265  0.02167  -0.02037 121 GLU A CB  
1508 C  CG  . GLU A 98  ? 0.13652 0.25295 0.23231 0.01661  0.03690  -0.04129 121 GLU A CG  
1509 C  CD  . GLU A 98  ? 0.12870 0.29713 0.27357 -0.00576 0.03260  -0.04667 121 GLU A CD  
1510 O  OE1 . GLU A 98  ? 0.13569 0.26785 0.27495 0.02454  0.01475  -0.04067 121 GLU A OE1 
1511 O  OE2 . GLU A 98  ? 0.14766 0.34374 0.31179 -0.00316 0.01457  -0.06121 121 GLU A OE2 
1518 N  N   . LEU A 99  ? 0.10141 0.17972 0.14527 -0.00947 0.03075  -0.00037 122 LEU A N   
1519 C  CA  . LEU A 99  ? 0.11536 0.16981 0.14458 0.00454  0.03376  -0.00164 122 LEU A CA  
1520 C  C   . LEU A 99  ? 0.11901 0.14985 0.13739 -0.00453 0.02098  -0.00139 122 LEU A C   
1521 O  O   . LEU A 99  ? 0.11714 0.16057 0.13334 -0.00893 0.02591  -0.00056 122 LEU A O   
1522 C  CB  . LEU A 99  ? 0.12592 0.16767 0.15900 -0.01115 0.04161  -0.00489 122 LEU A CB  
1523 C  CG  . LEU A 99  ? 0.11769 0.16308 0.17461 0.01391  0.05295  -0.01728 122 LEU A CG  
1524 C  CD1 . LEU A 99  ? 0.16033 0.18096 0.17884 0.00556  0.05639  -0.02177 122 LEU A CD1 
1525 C  CD2 . LEU A 99  ? 0.15049 0.16086 0.19112 0.00830  0.06101  -0.00521 122 LEU A CD2 
1537 N  N   . SER A 100 ? 0.12930 0.15430 0.14196 0.00283  0.02905  0.00499  123 SER A N   
1538 C  CA  . SER A 100 ? 0.10799 0.16018 0.15474 -0.01493 0.01960  0.00889  123 SER A CA  
1539 C  C   . SER A 100 ? 0.10521 0.16118 0.15547 -0.00504 0.02563  -0.00907 123 SER A C   
1540 O  O   . SER A 100 ? 0.12424 0.15393 0.15431 -0.00306 0.03745  -0.01356 123 SER A O   
1541 C  CB  . SER A 100 ? 0.13458 0.14320 0.15354 -0.00217 0.01320  0.02382  123 SER A CB  
1542 O  OG  . SER A 100 ? 0.15224 0.16963 0.14988 -0.00307 0.02085  0.02105  123 SER A OG  
1548 N  N   . ALA A 101 ? 0.08518 0.18380 0.15587 -0.00931 0.01680  -0.00744 124 ALA A N   
1549 C  CA  . ALA A 101 ? 0.11545 0.19074 0.15671 -0.02331 0.03008  -0.01987 124 ALA A CA  
1550 C  C   . ALA A 101 ? 0.11039 0.17855 0.14981 -0.01883 0.02978  -0.01467 124 ALA A C   
1551 O  O   . ALA A 101 ? 0.11176 0.19830 0.14941 -0.01871 0.02639  -0.02963 124 ALA A O   
1552 C  CB  . ALA A 101 ? 0.11185 0.18882 0.16426 -0.02941 0.01381  -0.00377 124 ALA A CB  
1558 N  N   . ALA A 102 ? 0.12079 0.17493 0.13714 -0.01412 0.01903  -0.01386 125 ALA A N   
1559 C  CA  . ALA A 102 ? 0.10849 0.17737 0.12714 0.00444  0.01534  -0.01786 125 ALA A CA  
1560 C  C   . ALA A 102 ? 0.09840 0.16728 0.12655 -0.00567 0.01641  -0.01474 125 ALA A C   
1561 O  O   . ALA A 102 ? 0.12180 0.17745 0.12974 -0.01434 0.01433  0.00427  125 ALA A O   
1562 C  CB  . ALA A 102 ? 0.11727 0.20368 0.13714 -0.00615 0.01413  -0.00856 125 ALA A CB  
1568 N  N   . ALA A 103 ? 0.11361 0.15271 0.11594 -0.00556 -0.00057 -0.01171 126 ALA A N   
1569 C  CA  . ALA A 103 ? 0.10376 0.16166 0.11499 0.00225  0.01430  0.00586  126 ALA A CA  
1570 C  C   . ALA A 103 ? 0.09509 0.15666 0.11139 -0.02018 0.01746  -0.00893 126 ALA A C   
1571 O  O   . ALA A 103 ? 0.10792 0.17086 0.11619 0.00274  0.01354  -0.00546 126 ALA A O   
1572 C  CB  . ALA A 103 ? 0.11528 0.17143 0.11336 0.00942  0.00665  0.00127  126 ALA A CB  
1578 N  N   . LEU A 104 ? 0.10875 0.16790 0.11602 -0.01484 0.02440  -0.00173 127 LEU A N   
1579 C  CA  . LEU A 104 ? 0.11403 0.12955 0.12342 -0.00840 0.01737  -0.00449 127 LEU A CA  
1580 C  C   . LEU A 104 ? 0.16071 0.14010 0.11853 -0.00890 0.00566  -0.00099 127 LEU A C   
1581 O  O   . LEU A 104 ? 0.17726 0.19570 0.10440 0.02119  -0.00359 -0.01664 127 LEU A O   
1582 C  CB  . LEU A 104 ? 0.12614 0.14386 0.13123 -0.00426 0.00971  -0.01072 127 LEU A CB  
1583 C  CG  . LEU A 104 ? 0.10831 0.17748 0.13355 -0.01499 0.00194  -0.00278 127 LEU A CG  
1584 C  CD1 . LEU A 104 ? 0.16743 0.18314 0.12523 -0.03985 -0.01187 -0.00698 127 LEU A CD1 
1585 C  CD2 . LEU A 104 ? 0.12087 0.24516 0.14654 0.00241  0.01080  0.00889  127 LEU A CD2 
1597 N  N   . GLN A 105 ? 0.13790 0.17353 0.12322 0.00336  -0.01336 -0.02193 128 GLN A N   
1598 C  CA  . GLN A 105 ? 0.13900 0.18643 0.12344 -0.02723 -0.01537 -0.01053 128 GLN A CA  
1599 C  C   . GLN A 105 ? 0.14324 0.22877 0.12565 -0.02781 -0.01066 -0.01313 128 GLN A C   
1600 O  O   . GLN A 105 ? 0.20537 0.24019 0.12934 -0.04514 -0.02635 -0.02068 128 GLN A O   
1601 C  CB  . GLN A 105 ? 0.15299 0.23398 0.13447 -0.01926 -0.02816 -0.01796 128 GLN A CB  
1602 C  CG  . GLN A 105 ? 0.15933 0.22982 0.15903 -0.00545 -0.02909 0.00376  128 GLN A CG  
1603 C  CD  . GLN A 105 ? 0.14777 0.26948 0.18823 -0.01662 -0.01938 0.00285  128 GLN A CD  
1604 O  OE1 . GLN A 105 ? 0.13908 0.31194 0.21347 -0.00536 0.00695  0.01470  128 GLN A OE1 
1605 N  NE2 . GLN A 105 ? 0.16048 0.25801 0.19560 -0.03048 -0.00513 0.00019  128 GLN A NE2 
1614 N  N   . TYR A 106 ? 0.14711 0.20678 0.12056 -0.01858 -0.00461 -0.01263 129 TYR A N   
1615 C  CA  . TYR A 106 ? 0.14574 0.21949 0.12874 -0.00177 -0.00950 -0.00333 129 TYR A CA  
1616 C  C   . TYR A 106 ? 0.15594 0.19619 0.12329 -0.01419 -0.00583 0.00119  129 TYR A C   
1617 O  O   . TYR A 106 ? 0.20127 0.23926 0.12933 -0.02745 -0.02587 0.01914  129 TYR A O   
1618 C  CB  . TYR A 106 ? 0.15000 0.23800 0.14855 -0.02319 -0.00664 -0.00331 129 TYR A CB  
1619 C  CG  . TYR A 106 ? 0.16879 0.25892 0.18934 -0.01331 -0.03348 -0.02188 129 TYR A CG  
1620 C  CD1 . TYR A 106 ? 0.20505 0.34826 0.21284 -0.02891 -0.05192 -0.02729 129 TYR A CD1 
1621 C  CD2 . TYR A 106 ? 0.15782 0.24552 0.21172 -0.02156 -0.01472 -0.03851 129 TYR A CD2 
1622 C  CE1 . TYR A 106 ? 0.19329 0.38774 0.23876 -0.03740 -0.04703 -0.03146 129 TYR A CE1 
1623 C  CE2 . TYR A 106 ? 0.18230 0.33374 0.23635 -0.01282 -0.01655 -0.03672 129 TYR A CE2 
1624 C  CZ  . TYR A 106 ? 0.18839 0.38247 0.25691 -0.05163 -0.04502 -0.05179 129 TYR A CZ  
1625 O  OH  . TYR A 106 ? 0.22407 0.46361 0.28745 -0.09477 -0.05192 -0.05861 129 TYR A OH  
1635 N  N   . SER A 107 ? 0.12875 0.18156 0.12084 -0.00499 0.00497  0.00974  130 SER A N   
1636 C  CA  . SER A 107 ? 0.12777 0.15993 0.12378 0.01778  0.01778  -0.00084 130 SER A CA  
1637 C  C   . SER A 107 ? 0.12802 0.14300 0.10857 0.00469  0.00838  -0.00368 130 SER A C   
1638 O  O   . SER A 107 ? 0.13115 0.16083 0.12567 -0.00656 0.01174  -0.00088 130 SER A O   
1639 C  CB  . SER A 107 ? 0.15604 0.19223 0.13737 -0.00578 0.03231  -0.00344 130 SER A CB  
1640 O  OG  . SER A 107 ? 0.16433 0.17792 0.14204 -0.00846 0.02594  0.00547  130 SER A OG  
1646 N  N   . ASP A 108 ? 0.10394 0.15938 0.11390 -0.00138 0.00255  -0.01849 131 ASP A N   
1647 C  CA  . ASP A 108 ? 0.10909 0.16258 0.11593 -0.00650 0.00381  -0.00761 131 ASP A CA  
1648 C  C   . ASP A 108 ? 0.11528 0.15081 0.11680 -0.00107 0.00747  -0.00914 131 ASP A C   
1649 O  O   . ASP A 108 ? 0.11494 0.16036 0.11721 -0.00026 -0.00185 -0.00317 131 ASP A O   
1650 C  CB  . ASP A 108 ? 0.10644 0.16134 0.13139 -0.00439 0.00353  -0.01118 131 ASP A CB  
1651 C  CG  . ASP A 108 ? 0.11167 0.17807 0.13596 0.02933  -0.00038 -0.01632 131 ASP A CG  
1652 O  OD1 . ASP A 108 ? 0.11748 0.17091 0.13571 0.00609  -0.00156 -0.00424 131 ASP A OD1 
1653 O  OD2 . ASP A 108 ? 0.14705 0.20093 0.14787 0.03247  -0.02254 -0.02731 131 ASP A OD2 
1658 N  N   . ASN A 109 ? 0.10478 0.15236 0.11722 -0.00294 -0.00481 0.00712  132 ASN A N   
1659 C  CA  . ASN A 109 ? 0.10739 0.16184 0.11799 -0.00339 -0.00822 0.00089  132 ASN A CA  
1660 C  C   . ASN A 109 ? 0.10416 0.15648 0.11611 -0.00224 0.00136  0.00231  132 ASN A C   
1661 O  O   . ASN A 109 ? 0.11037 0.16863 0.11010 -0.00289 0.00424  -0.00527 132 ASN A O   
1662 C  CB  . ASN A 109 ? 0.12037 0.16051 0.11124 0.00460  0.00970  0.00473  132 ASN A CB  
1663 C  CG  . ASN A 109 ? 0.13925 0.19602 0.11728 -0.00038 0.01539  0.00942  132 ASN A CG  
1664 O  OD1 . ASN A 109 ? 0.14193 0.18177 0.15580 -0.00360 0.02513  -0.00712 132 ASN A OD1 
1665 N  ND2 . ASN A 109 ? 0.17743 0.22241 0.11929 0.00748  0.03014  0.02935  132 ASN A ND2 
1672 N  N   . VAL A 110 ? 0.12164 0.14931 0.10923 0.00531  0.00781  0.00596  133 VAL A N   
1673 C  CA  . VAL A 110 ? 0.10141 0.16164 0.12204 -0.00727 0.01409  0.00036  133 VAL A CA  
1674 C  C   . VAL A 110 ? 0.10154 0.15597 0.11924 -0.00676 -0.00113 -0.00787 133 VAL A C   
1675 O  O   . VAL A 110 ? 0.11389 0.15583 0.11402 -0.00172 0.00531  -0.00659 133 VAL A O   
1676 C  CB  . VAL A 110 ? 0.11797 0.15460 0.13285 -0.00294 0.00366  -0.00789 133 VAL A CB  
1677 C  CG1 . VAL A 110 ? 0.14023 0.16008 0.14020 0.00439  0.01575  -0.00807 133 VAL A CG1 
1678 C  CG2 . VAL A 110 ? 0.15540 0.17247 0.14243 0.00249  0.01628  -0.00196 133 VAL A CG2 
1688 N  N   . ALA A 111 ? 0.10192 0.16212 0.10753 -0.00402 0.00132  0.00221  134 ALA A N   
1689 C  CA  . ALA A 111 ? 0.10545 0.14335 0.10246 -0.00058 0.00625  -0.00759 134 ALA A CA  
1690 C  C   . ALA A 111 ? 0.10212 0.15289 0.10758 -0.00471 0.00933  -0.00007 134 ALA A C   
1691 O  O   . ALA A 111 ? 0.10509 0.15859 0.10387 0.00180  0.00783  -0.01221 134 ALA A O   
1692 C  CB  . ALA A 111 ? 0.10803 0.15018 0.11831 -0.00273 0.00576  0.01164  134 ALA A CB  
1698 N  N   . MET A 112 ? 0.10652 0.15773 0.09801 0.00707  0.00086  -0.00436 135 MET A N   
1699 C  CA  . MET A 112 ? 0.10223 0.14559 0.09371 0.01513  0.01493  -0.00335 135 MET A CA  
1700 C  C   . MET A 112 ? 0.09503 0.15874 0.09412 0.01805  0.01670  -0.01384 135 MET A C   
1701 O  O   . MET A 112 ? 0.11129 0.17365 0.08847 0.01169  0.00434  -0.01431 135 MET A O   
1702 C  CB  . MET A 112 ? 0.09779 0.15782 0.09320 -0.00379 0.00661  -0.02214 135 MET A CB  
1703 C  CG  . MET A 112 ? 0.10266 0.15501 0.10311 0.00107  0.00861  -0.01006 135 MET A CG  
1704 S  SD  . MET A 112 ? 0.11594 0.15099 0.10426 -0.00228 0.00836  -0.00657 135 MET A SD  
1705 C  CE  . MET A 112 ? 0.12566 0.15627 0.11246 0.00119  0.01167  -0.01759 135 MET A CE  
1715 N  N   . ASN A 113 ? 0.10682 0.15907 0.09942 0.00501  0.00584  -0.00842 136 ASN A N   
1716 C  CA  . ASN A 113 ? 0.09026 0.18092 0.10670 0.00468  0.01243  -0.01764 136 ASN A CA  
1717 C  C   . ASN A 113 ? 0.11841 0.17909 0.11422 0.00542  0.00999  -0.02190 136 ASN A C   
1718 O  O   . ASN A 113 ? 0.10779 0.20439 0.10653 0.01285  0.00933  -0.04486 136 ASN A O   
1719 C  CB  . ASN A 113 ? 0.10329 0.14727 0.11003 -0.00178 0.00963  -0.01771 136 ASN A CB  
1720 C  CG  . ASN A 113 ? 0.12055 0.14077 0.12070 -0.00496 0.01388  -0.02320 136 ASN A CG  
1721 O  OD1 . ASN A 113 ? 0.11992 0.17031 0.13535 -0.00028 0.02890  -0.01698 136 ASN A OD1 
1722 N  ND2 . ASN A 113 ? 0.14146 0.16210 0.13425 -0.00556 0.04177  -0.00964 136 ASN A ND2 
1729 N  N   . LYS A 114 ? 0.08333 0.17036 0.11213 0.00320  0.00821  -0.00913 137 LYS A N   
1730 C  CA  . LYS A 114 ? 0.10619 0.18550 0.10622 0.01214  0.01247  -0.01390 137 LYS A CA  
1731 C  C   . LYS A 114 ? 0.10564 0.20244 0.10465 -0.00280 0.02143  -0.01329 137 LYS A C   
1732 O  O   . LYS A 114 ? 0.13062 0.19716 0.09404 -0.00012 0.01858  -0.02091 137 LYS A O   
1733 C  CB  . LYS A 114 ? 0.10007 0.17978 0.09841 -0.00428 0.00970  -0.01708 137 LYS A CB  
1734 C  CG  . LYS A 114 ? 0.10394 0.20026 0.10821 -0.01019 0.01475  -0.02560 137 LYS A CG  
1735 C  CD  . LYS A 114 ? 0.12421 0.19553 0.10860 -0.00368 0.01045  -0.02407 137 LYS A CD  
1736 C  CE  . LYS A 114 ? 0.15872 0.19372 0.11709 0.02865  -0.01084 -0.03735 137 LYS A CE  
1737 N  NZ  . LYS A 114 ? 0.22537 0.21008 0.12649 0.01982  -0.01698 -0.01223 137 LYS A NZ  
1751 N  N   . LEU A 115 ? 0.11650 0.18290 0.09350 -0.00602 -0.00367 -0.00906 138 LEU A N   
1752 C  CA  . LEU A 115 ? 0.12837 0.18551 0.10453 -0.01318 0.02015  0.01316  138 LEU A CA  
1753 C  C   . LEU A 115 ? 0.10378 0.19389 0.10259 0.00844  -0.00454 0.01092  138 LEU A C   
1754 O  O   . LEU A 115 ? 0.14174 0.21230 0.09531 0.01515  -0.00858 0.00130  138 LEU A O   
1755 C  CB  . LEU A 115 ? 0.13134 0.17131 0.10574 0.00847  0.01033  0.00914  138 LEU A CB  
1756 C  CG  . LEU A 115 ? 0.13583 0.16727 0.12389 -0.01431 -0.00270 -0.00138 138 LEU A CG  
1757 C  CD1 . LEU A 115 ? 0.15554 0.18805 0.12443 -0.03680 0.00228  -0.00362 138 LEU A CD1 
1758 C  CD2 . LEU A 115 ? 0.16135 0.22230 0.14356 -0.01146 0.02115  -0.01499 138 LEU A CD2 
1770 N  N   . ILE A 116 ? 0.09414 0.19339 0.10253 -0.00652 0.01291  -0.00587 139 ILE A N   
1771 C  CA  . ILE A 116 ? 0.11390 0.17757 0.10356 0.00725  0.00809  -0.00785 139 ILE A CA  
1772 C  C   . ILE A 116 ? 0.11094 0.23210 0.10749 0.02925  -0.00203 -0.02113 139 ILE A C   
1773 O  O   . ILE A 116 ? 0.12633 0.23119 0.09721 0.01233  -0.00667 -0.02237 139 ILE A O   
1774 C  CB  . ILE A 116 ? 0.10211 0.20187 0.09650 -0.00503 0.00070  -0.01696 139 ILE A CB  
1775 C  CG1 . ILE A 116 ? 0.10969 0.19338 0.10582 0.01443  -0.00595 -0.02068 139 ILE A CG1 
1776 C  CG2 . ILE A 116 ? 0.11837 0.22255 0.10826 -0.00339 -0.00586 -0.02246 139 ILE A CG2 
1777 C  CD1 . ILE A 116 ? 0.12265 0.18712 0.10316 0.01175  -0.00626 -0.01953 139 ILE A CD1 
1789 N  N   . ALA A 117 ? 0.12935 0.22118 0.11418 0.01960  -0.00417 -0.02714 140 ALA A N   
1790 C  CA  . ALA A 117 ? 0.15177 0.24414 0.11717 -0.00888 0.01404  -0.02583 140 ALA A CA  
1791 C  C   . ALA A 117 ? 0.15332 0.23212 0.11485 -0.00053 0.01282  -0.03474 140 ALA A C   
1792 O  O   . ALA A 117 ? 0.18115 0.25329 0.10943 -0.02134 0.00053  -0.03574 140 ALA A O   
1793 C  CB  . ALA A 117 ? 0.18179 0.23849 0.12073 0.00547  0.01380  -0.03512 140 ALA A CB  
1799 N  N   A HIS A 118 ? 0.14029 0.23822 0.11235 -0.01443 0.02558  -0.02466 141 HIS A N   
1800 N  N   B HIS A 118 ? 0.15046 0.23619 0.11493 0.01154  0.02643  -0.03841 141 HIS A N   
1801 C  CA  A HIS A 118 ? 0.16908 0.27527 0.12680 -0.02883 0.03168  -0.00332 141 HIS A CA  
1802 C  CA  B HIS A 118 ? 0.16728 0.26771 0.12677 0.01943  0.03430  -0.03011 141 HIS A CA  
1803 C  C   A HIS A 118 ? 0.15147 0.27319 0.12134 -0.01716 0.01733  0.00861  141 HIS A C   
1804 C  C   B HIS A 118 ? 0.17970 0.29509 0.13045 0.03696  0.04230  -0.00551 141 HIS A C   
1805 O  O   A HIS A 118 ? 0.16839 0.27792 0.10391 -0.03922 0.00670  0.00763  141 HIS A O   
1806 O  O   B HIS A 118 ? 0.16694 0.32990 0.14789 0.07144  0.05787  0.00340  141 HIS A O   
1807 C  CB  A HIS A 118 ? 0.21993 0.31200 0.14694 -0.07716 0.03171  0.00584  141 HIS A CB  
1808 C  CB  B HIS A 118 ? 0.18102 0.26842 0.13528 -0.02678 0.01388  -0.04012 141 HIS A CB  
1809 C  CG  A HIS A 118 ? 0.27968 0.38041 0.17345 -0.08131 0.03682  0.01061  141 HIS A CG  
1810 C  CG  B HIS A 118 ? 0.18511 0.28044 0.15444 -0.03055 0.00431  -0.04658 141 HIS A CG  
1811 N  ND1 A HIS A 118 ? 0.28788 0.39421 0.18462 -0.05086 0.03933  -0.00284 141 HIS A ND1 
1812 N  ND1 B HIS A 118 ? 0.20199 0.30866 0.16968 -0.02160 0.00521  -0.04222 141 HIS A ND1 
1813 C  CD2 A HIS A 118 ? 0.32781 0.41843 0.18566 -0.06470 0.03532  0.02000  141 HIS A CD2 
1814 C  CD2 B HIS A 118 ? 0.18330 0.28114 0.16171 -0.02220 -0.00293 -0.04892 141 HIS A CD2 
1815 C  CE1 A HIS A 118 ? 0.31126 0.41837 0.18773 -0.08915 0.03522  0.00892  141 HIS A CE1 
1816 C  CE1 B HIS A 118 ? 0.18515 0.27767 0.16763 -0.00421 -0.00114 -0.05409 141 HIS A CE1 
1817 N  NE2 A HIS A 118 ? 0.32764 0.43858 0.19033 -0.06268 0.03651  0.01689  141 HIS A NE2 
1818 N  NE2 B HIS A 118 ? 0.18025 0.28567 0.16971 0.01726  -0.00592 -0.06682 141 HIS A NE2 
1833 N  N   . VAL A 119 ? 0.14859 0.26913 0.13020 0.01419  0.00611  -0.00497 142 VAL A N   
1834 C  CA  . VAL A 119 ? 0.20592 0.30572 0.14713 0.03430  0.00054  -0.00390 142 VAL A CA  
1835 C  C   . VAL A 119 ? 0.20694 0.33676 0.13191 0.06221  -0.00038 -0.00874 142 VAL A C   
1836 O  O   . VAL A 119 ? 0.24317 0.36676 0.12692 0.11543  -0.01007 0.00107  142 VAL A O   
1837 C  CB  . VAL A 119 ? 0.26227 0.33353 0.19063 0.05454  -0.00773 -0.05192 142 VAL A CB  
1838 C  CG1 . VAL A 119 ? 0.28727 0.34944 0.22182 0.00270  -0.01314 -0.05400 142 VAL A CG1 
1839 C  CG2 . VAL A 119 ? 0.21843 0.30038 0.17733 0.04582  0.00002  -0.07829 142 VAL A CG2 
1850 N  N   . GLY A 120 ? 0.17873 0.32612 0.13140 0.02807  -0.02714 -0.04297 143 GLY A N   
1851 C  CA  . GLY A 120 ? 0.17558 0.37415 0.11941 0.02664  -0.02747 -0.05089 143 GLY A CA  
1852 C  C   . GLY A 120 ? 0.17300 0.42276 0.12243 0.01788  -0.01239 -0.06154 143 GLY A C   
1853 O  O   . GLY A 120 ? 0.18490 0.57937 0.16240 -0.06376 0.00313  -0.06749 143 GLY A O   
1857 N  N   . GLY A 121 ? 0.15168 0.29598 0.10807 0.05169  -0.02483 -0.06343 144 GLY A N   
1858 C  CA  . GLY A 121 ? 0.16118 0.24548 0.11902 0.04496  -0.00994 -0.05203 144 GLY A CA  
1859 C  C   . GLY A 121 ? 0.11876 0.21929 0.11640 0.03367  -0.02069 -0.05086 144 GLY A C   
1860 O  O   . GLY A 121 ? 0.12743 0.23509 0.12689 0.00047  0.00197  -0.05576 144 GLY A O   
1864 N  N   . PRO A 122 ? 0.12778 0.20532 0.13151 0.01030  -0.01543 -0.05976 145 PRO A N   
1865 C  CA  . PRO A 122 ? 0.13830 0.16900 0.14830 -0.01346 0.01698  -0.04826 145 PRO A CA  
1866 C  C   . PRO A 122 ? 0.13572 0.16054 0.15055 -0.01479 0.04602  -0.02851 145 PRO A C   
1867 O  O   . PRO A 122 ? 0.21682 0.14243 0.13549 -0.04678 0.07109  -0.03216 145 PRO A O   
1868 C  CB  . PRO A 122 ? 0.13340 0.18117 0.16588 -0.01436 0.03657  -0.04255 145 PRO A CB  
1869 C  CG  . PRO A 122 ? 0.13928 0.19282 0.15337 -0.00861 0.00978  -0.04596 145 PRO A CG  
1870 C  CD  . PRO A 122 ? 0.14597 0.19702 0.13802 0.00032  -0.01680 -0.06113 145 PRO A CD  
1878 N  N   . ALA A 123 ? 0.13557 0.15755 0.18996 -0.01386 0.00055  -0.03576 146 ALA A N   
1879 C  CA  . ALA A 123 ? 0.12591 0.17314 0.20004 0.00249  -0.01002 -0.03605 146 ALA A CA  
1880 C  C   . ALA A 123 ? 0.11635 0.17651 0.18034 -0.01788 -0.01283 -0.05112 146 ALA A C   
1881 O  O   . ALA A 123 ? 0.12934 0.17972 0.18422 -0.01058 0.00538  -0.02808 146 ALA A O   
1882 C  CB  . ALA A 123 ? 0.12182 0.20615 0.21084 -0.02657 -0.00586 -0.02885 146 ALA A CB  
1888 N  N   . SER A 124 ? 0.12291 0.20361 0.15054 -0.00267 0.01256  -0.06889 147 SER A N   
1889 C  CA  A SER A 124 ? 0.12777 0.23462 0.14347 -0.00882 0.02981  -0.05072 147 SER A CA  
1890 C  CA  B SER A 124 ? 0.13384 0.23738 0.14584 0.00442  0.02283  -0.06882 147 SER A CA  
1891 C  C   . SER A 124 ? 0.12714 0.22007 0.12047 -0.01046 0.01406  -0.03991 147 SER A C   
1892 O  O   . SER A 124 ? 0.14820 0.22048 0.10779 -0.00874 0.01873  -0.02126 147 SER A O   
1893 C  CB  A SER A 124 ? 0.11979 0.25900 0.15403 -0.03243 0.03942  -0.03065 147 SER A CB  
1894 C  CB  B SER A 124 ? 0.12881 0.27040 0.16045 0.01119  0.02973  -0.09040 147 SER A CB  
1895 O  OG  A SER A 124 ? 0.15456 0.27644 0.16278 0.00952  0.04012  -0.00689 147 SER A OG  
1896 O  OG  B SER A 124 ? 0.14363 0.30691 0.17371 0.02606  0.02620  -0.10536 147 SER A OG  
1907 N  N   . VAL A 125 ? 0.13032 0.18206 0.10413 0.00180  0.00019  0.00049  148 VAL A N   
1908 C  CA  . VAL A 125 ? 0.11373 0.17902 0.10897 -0.02071 0.00119  -0.00406 148 VAL A CA  
1909 C  C   . VAL A 125 ? 0.09984 0.17943 0.09513 -0.03469 -0.01477 -0.01012 148 VAL A C   
1910 O  O   . VAL A 125 ? 0.12823 0.16519 0.09485 -0.03210 -0.01652 -0.00364 148 VAL A O   
1911 C  CB  . VAL A 125 ? 0.11807 0.17198 0.11955 -0.00177 -0.01469 0.00339  148 VAL A CB  
1912 C  CG1 . VAL A 125 ? 0.12932 0.17738 0.11616 0.00110  -0.01897 -0.00661 148 VAL A CG1 
1913 C  CG2 . VAL A 125 ? 0.12187 0.19768 0.11270 -0.01754 -0.01100 0.00121  148 VAL A CG2 
1923 N  N   . THR A 126 ? 0.11737 0.16308 0.09841 -0.01660 -0.01561 -0.00595 149 THR A N   
1924 C  CA  . THR A 126 ? 0.11493 0.15160 0.07909 -0.01311 -0.00539 -0.01275 149 THR A CA  
1925 C  C   . THR A 126 ? 0.11761 0.16084 0.07743 -0.00093 -0.00278 -0.01006 149 THR A C   
1926 O  O   . THR A 126 ? 0.11984 0.17547 0.08728 -0.01076 -0.00195 -0.00550 149 THR A O   
1927 C  CB  . THR A 126 ? 0.11987 0.15231 0.09310 -0.00416 -0.00678 -0.02202 149 THR A CB  
1928 O  OG1 . THR A 126 ? 0.12985 0.16910 0.09763 -0.00783 0.01094  -0.01659 149 THR A OG1 
1929 C  CG2 . THR A 126 ? 0.13493 0.18018 0.09505 -0.02257 0.00469  -0.02098 149 THR A CG2 
1937 N  N   . ALA A 127 ? 0.12172 0.19549 0.08278 0.01199  -0.01736 -0.01450 150 ALA A N   
1938 C  CA  . ALA A 127 ? 0.13328 0.22862 0.08695 -0.01787 -0.00829 -0.01895 150 ALA A CA  
1939 C  C   . ALA A 127 ? 0.13033 0.23545 0.07807 -0.00952 -0.01526 -0.00474 150 ALA A C   
1940 O  O   . ALA A 127 ? 0.14090 0.24715 0.08134 0.00307  -0.00876 0.01544  150 ALA A O   
1941 C  CB  . ALA A 127 ? 0.17001 0.24269 0.08764 -0.05492 0.01367  -0.02356 150 ALA A CB  
1947 N  N   . PHE A 128 ? 0.12753 0.21360 0.07660 -0.00578 0.00073  0.00739  151 PHE A N   
1948 C  CA  . PHE A 128 ? 0.11804 0.21782 0.09369 0.00497  0.00072  0.02142  151 PHE A CA  
1949 C  C   . PHE A 128 ? 0.11218 0.18187 0.09373 0.00604  -0.00243 0.02836  151 PHE A C   
1950 O  O   . PHE A 128 ? 0.12887 0.19648 0.10798 0.00151  0.00105  0.04215  151 PHE A O   
1951 C  CB  . PHE A 128 ? 0.12153 0.24051 0.11185 -0.00199 -0.01360 0.03759  151 PHE A CB  
1952 C  CG  . PHE A 128 ? 0.11492 0.23244 0.12895 0.01765  -0.01412 0.00661  151 PHE A CG  
1953 C  CD1 . PHE A 128 ? 0.12924 0.26084 0.14226 -0.00122 -0.00883 -0.02921 151 PHE A CD1 
1954 C  CD2 . PHE A 128 ? 0.14861 0.21988 0.13665 0.02853  -0.01734 -0.00835 151 PHE A CD2 
1955 C  CE1 . PHE A 128 ? 0.12677 0.28338 0.15523 -0.00277 0.01939  -0.03537 151 PHE A CE1 
1956 C  CE2 . PHE A 128 ? 0.16733 0.26011 0.15249 0.05173  -0.03068 -0.02871 151 PHE A CE2 
1957 C  CZ  . PHE A 128 ? 0.12538 0.28804 0.16395 0.03782  -0.00713 -0.03639 151 PHE A CZ  
1967 N  N   . ALA A 129 ? 0.10634 0.18698 0.08283 -0.01180 0.00015  0.01855  152 ALA A N   
1968 C  CA  . ALA A 129 ? 0.12301 0.16346 0.08725 -0.01235 -0.00915 0.01823  152 ALA A CA  
1969 C  C   . ALA A 129 ? 0.11689 0.16800 0.09047 -0.00049 -0.00334 0.01697  152 ALA A C   
1970 O  O   . ALA A 129 ? 0.13339 0.17883 0.10818 -0.00487 0.00322  0.02582  152 ALA A O   
1971 C  CB  . ALA A 129 ? 0.15148 0.15983 0.08958 -0.03978 -0.00665 0.01314  152 ALA A CB  
1977 N  N   . ARG A 130 ? 0.13022 0.23220 0.09335 0.00761  -0.01286 0.00646  153 ARG A N   
1978 C  CA  . ARG A 130 ? 0.14425 0.28540 0.10574 0.03947  -0.02021 -0.00980 153 ARG A CA  
1979 C  C   . ARG A 130 ? 0.14044 0.28591 0.11337 0.08372  0.00228  0.02464  153 ARG A C   
1980 O  O   . ARG A 130 ? 0.18581 0.31538 0.10887 0.10196  -0.00320 0.02916  153 ARG A O   
1981 C  CB  . ARG A 130 ? 0.14432 0.28360 0.12107 0.03130  -0.02386 -0.02637 153 ARG A CB  
1982 C  CG  . ARG A 130 ? 0.16060 0.27669 0.13112 0.02624  -0.02110 -0.03216 153 ARG A CG  
1983 C  CD  . ARG A 130 ? 0.15274 0.28738 0.13200 0.03083  -0.02335 -0.01710 153 ARG A CD  
1984 N  NE  . ARG A 130 ? 0.13562 0.28191 0.14213 -0.00246 -0.02579 -0.01169 153 ARG A NE  
1985 C  CZ  . ARG A 130 ? 0.13074 0.22317 0.12911 0.01229  -0.00177 -0.01296 153 ARG A CZ  
1986 N  NH1 . ARG A 130 ? 0.14375 0.18093 0.11545 -0.00602 -0.02606 -0.02835 153 ARG A NH1 
1987 N  NH2 . ARG A 130 ? 0.15813 0.22202 0.15707 -0.00873 0.00513  -0.01063 153 ARG A NH2 
2001 N  N   . GLN A 131 ? 0.15458 0.29713 0.13261 0.06480  0.02121  0.07916  154 GLN A N   
2002 C  CA  . GLN A 131 ? 0.18934 0.33763 0.17042 0.08956  0.05783  0.11147  154 GLN A CA  
2003 C  C   . GLN A 131 ? 0.17665 0.32189 0.19634 0.04803  0.03218  0.13928  154 GLN A C   
2004 O  O   . GLN A 131 ? 0.17575 0.37452 0.21762 0.05517  0.04244  0.15475  154 GLN A O   
2005 C  CB  . GLN A 131 ? 0.26025 0.35636 0.18809 0.13154  0.07671  0.09760  154 GLN A CB  
2006 C  CG  . GLN A 131 ? 0.31209 0.35959 0.20932 0.11911  0.07957  0.04572  154 GLN A CG  
2007 C  CD  . GLN A 131 ? 0.34210 0.28748 0.22306 0.12192  0.05031  0.01990  154 GLN A CD  
2008 O  OE1 . GLN A 131 ? 0.33508 0.24870 0.22800 0.08516  0.01266  -0.04203 154 GLN A OE1 
2009 N  NE2 . GLN A 131 ? 0.36813 0.24608 0.23313 0.09473  0.07538  0.05243  154 GLN A NE2 
2018 N  N   . LEU A 132 ? 0.15453 0.32505 0.20448 0.02357  0.01432  0.13081  155 LEU A N   
2019 C  CA  . LEU A 132 ? 0.16237 0.28687 0.21820 0.02009  -0.00681 0.11371  155 LEU A CA  
2020 C  C   . LEU A 132 ? 0.19177 0.26278 0.22658 0.03437  -0.00267 0.08537  155 LEU A C   
2021 O  O   . LEU A 132 ? 0.23324 0.27903 0.27510 0.04362  -0.01670 0.05819  155 LEU A O   
2022 C  CB  . LEU A 132 ? 0.18436 0.28925 0.21959 -0.02810 0.00184  0.06621  155 LEU A CB  
2023 C  CG  . LEU A 132 ? 0.18965 0.27304 0.21579 0.00324  -0.01086 0.04058  155 LEU A CG  
2024 C  CD1 . LEU A 132 ? 0.20231 0.27764 0.20687 0.03610  -0.02368 0.01318  155 LEU A CD1 
2025 C  CD2 . LEU A 132 ? 0.17869 0.28367 0.22203 -0.00702 0.00434  0.02750  155 LEU A CD2 
2037 N  N   . GLY A 133 ? 0.16624 0.27346 0.17908 0.01322  -0.00120 0.11226  156 GLY A N   
2038 C  CA  . GLY A 133 ? 0.16486 0.26257 0.17154 0.02229  -0.03274 0.08654  156 GLY A CA  
2039 C  C   . GLY A 133 ? 0.15243 0.24846 0.16276 0.03326  -0.00657 0.05841  156 GLY A C   
2040 O  O   . GLY A 133 ? 0.20726 0.27097 0.18778 0.07195  0.00592  0.07827  156 GLY A O   
2044 N  N   . ASP A 134 ? 0.13883 0.18878 0.12442 0.01658  -0.02128 0.02567  157 ASP A N   
2045 C  CA  . ASP A 134 ? 0.13127 0.17656 0.10911 -0.00645 0.00011  0.00838  157 ASP A CA  
2046 C  C   . ASP A 134 ? 0.12591 0.16715 0.10447 0.02634  -0.01258 -0.00083 157 ASP A C   
2047 O  O   . ASP A 134 ? 0.12645 0.19605 0.10520 0.00278  -0.00760 0.00859  157 ASP A O   
2048 C  CB  . ASP A 134 ? 0.13190 0.16701 0.09856 -0.02107 0.00065  0.02435  157 ASP A CB  
2049 C  CG  . ASP A 134 ? 0.12266 0.17398 0.10028 -0.00943 -0.00490 0.00764  157 ASP A CG  
2050 O  OD1 . ASP A 134 ? 0.12300 0.16691 0.09620 -0.00660 0.00169  0.01333  157 ASP A OD1 
2051 O  OD2 . ASP A 134 ? 0.12679 0.18228 0.09290 -0.01897 -0.01069 -0.00601 157 ASP A OD2 
2056 N  N   . GLU A 135 ? 0.11804 0.17394 0.11337 0.01684  -0.02993 -0.00342 158 GLU A N   
2057 C  CA  . GLU A 135 ? 0.13281 0.20476 0.12439 -0.01838 -0.02646 0.01178  158 GLU A CA  
2058 C  C   . GLU A 135 ? 0.11109 0.22452 0.11732 -0.00170 -0.02429 0.00340  158 GLU A C   
2059 O  O   . GLU A 135 ? 0.15613 0.31901 0.11344 -0.05177 -0.01451 0.00047  158 GLU A O   
2060 C  CB  . GLU A 135 ? 0.14864 0.27548 0.15394 -0.04570 -0.03280 0.00783  158 GLU A CB  
2061 C  CG  . GLU A 135 ? 0.18632 0.27592 0.15832 -0.00873 -0.04392 0.03948  158 GLU A CG  
2062 C  CD  . GLU A 135 ? 0.18687 0.31186 0.15396 -0.00556 -0.01880 0.02580  158 GLU A CD  
2063 O  OE1 . GLU A 135 ? 0.17616 0.37967 0.18259 0.06244  -0.02805 0.04133  158 GLU A OE1 
2064 O  OE2 . GLU A 135 ? 0.23240 0.35474 0.15225 -0.00693 -0.02221 0.04287  158 GLU A OE2 
2071 N  N   . THR A 136 ? 0.11126 0.16828 0.11892 -0.00339 -0.00401 0.00926  159 THR A N   
2072 C  CA  . THR A 136 ? 0.10772 0.17501 0.11350 -0.01591 0.00867  -0.01082 159 THR A CA  
2073 C  C   . THR A 136 ? 0.09848 0.15566 0.09421 -0.00175 0.00553  0.00069  159 THR A C   
2074 O  O   . THR A 136 ? 0.11968 0.17337 0.10576 -0.02222 0.01140  -0.00879 159 THR A O   
2075 C  CB  . THR A 136 ? 0.12380 0.20412 0.12132 0.01684  -0.00156 -0.03193 159 THR A CB  
2076 O  OG1 . THR A 136 ? 0.15267 0.22871 0.14596 0.02275  -0.00511 -0.02879 159 THR A OG1 
2077 C  CG2 . THR A 136 ? 0.12947 0.20899 0.12093 -0.00061 -0.00192 -0.03182 159 THR A CG2 
2085 N  N   . PHE A 137 ? 0.09705 0.17140 0.09167 -0.00121 0.00042  -0.00229 160 PHE A N   
2086 C  CA  . PHE A 137 ? 0.09681 0.15546 0.08178 -0.00712 0.00834  0.01145  160 PHE A CA  
2087 C  C   . PHE A 137 ? 0.11231 0.15843 0.08501 -0.00959 0.00367  -0.00784 160 PHE A C   
2088 O  O   . PHE A 137 ? 0.13150 0.16834 0.08177 -0.00177 -0.00540 -0.00538 160 PHE A O   
2089 C  CB  . PHE A 137 ? 0.11665 0.15046 0.09910 -0.01473 0.00495  -0.00429 160 PHE A CB  
2090 C  CG  . PHE A 137 ? 0.10355 0.15168 0.08259 -0.01252 0.00496  0.00114  160 PHE A CG  
2091 C  CD1 . PHE A 137 ? 0.13363 0.15027 0.08883 -0.01727 -0.00576 0.00747  160 PHE A CD1 
2092 C  CD2 . PHE A 137 ? 0.09657 0.16597 0.08280 -0.01332 0.00434  0.00630  160 PHE A CD2 
2093 C  CE1 . PHE A 137 ? 0.13791 0.14700 0.09938 0.00358  0.00509  -0.00202 160 PHE A CE1 
2094 C  CE2 . PHE A 137 ? 0.10824 0.16397 0.09083 -0.01313 0.01526  0.00893  160 PHE A CE2 
2095 C  CZ  . PHE A 137 ? 0.11531 0.17177 0.10418 -0.01094 0.01445  0.00126  160 PHE A CZ  
2105 N  N   . ARG A 138 ? 0.12260 0.15300 0.07561 -0.00773 0.00630  -0.03074 161 ARG A N   
2106 C  CA  . ARG A 138 ? 0.11425 0.16486 0.09190 0.00243  0.01199  -0.02946 161 ARG A CA  
2107 C  C   . ARG A 138 ? 0.10732 0.14770 0.09201 -0.02673 0.01079  -0.01695 161 ARG A C   
2108 O  O   . ARG A 138 ? 0.16460 0.17293 0.09371 -0.01117 0.00341  -0.00815 161 ARG A O   
2109 C  CB  . ARG A 138 ? 0.15530 0.17349 0.12168 -0.00606 0.00646  -0.01934 161 ARG A CB  
2110 C  CG  . ARG A 138 ? 0.16246 0.17134 0.12473 -0.00652 0.00390  -0.02336 161 ARG A CG  
2111 C  CD  . ARG A 138 ? 0.12404 0.17334 0.12913 -0.02862 0.01877  -0.02026 161 ARG A CD  
2112 N  NE  . ARG A 138 ? 0.13353 0.18214 0.12415 -0.02689 0.00327  -0.02034 161 ARG A NE  
2113 C  CZ  . ARG A 138 ? 0.15176 0.19960 0.13530 -0.03274 -0.00019 -0.00656 161 ARG A CZ  
2114 N  NH1 . ARG A 138 ? 0.13374 0.24876 0.14959 -0.02749 0.00244  -0.01387 161 ARG A NH1 
2115 N  NH2 . ARG A 138 ? 0.16384 0.22445 0.16588 -0.06535 -0.00773 -0.00377 161 ARG A NH2 
2129 N  N   . LEU A 139 ? 0.11273 0.15517 0.08862 -0.01530 0.01466  -0.01634 162 LEU A N   
2130 C  CA  . LEU A 139 ? 0.12082 0.14028 0.08437 0.00422  -0.00030 -0.01383 162 LEU A CA  
2131 C  C   . LEU A 139 ? 0.12505 0.15047 0.10806 -0.00990 0.00401  -0.01428 162 LEU A C   
2132 O  O   . LEU A 139 ? 0.14486 0.16019 0.11130 -0.01473 -0.00328 -0.01346 162 LEU A O   
2133 C  CB  . LEU A 139 ? 0.12069 0.14080 0.09010 0.00749  0.00669  -0.00231 162 LEU A CB  
2134 C  CG  . LEU A 139 ? 0.12269 0.16416 0.11496 -0.01430 0.00840  0.00056  162 LEU A CG  
2135 C  CD1 . LEU A 139 ? 0.12742 0.21190 0.12041 -0.03242 0.00637  0.02767  162 LEU A CD1 
2136 C  CD2 . LEU A 139 ? 0.11833 0.17521 0.13641 0.00740  0.01197  0.00083  162 LEU A CD2 
2148 N  N   A ASP A 140 ? 0.12238 0.13453 0.11605 -0.01444 0.00848  -0.01010 163 ASP A N   
2149 N  N   B ASP A 140 ? 0.13344 0.16992 0.11840 -0.01840 -0.00230 -0.01661 163 ASP A N   
2150 C  CA  A ASP A 140 ? 0.10305 0.15905 0.11511 -0.02822 0.01265  -0.01649 163 ASP A CA  
2151 C  CA  B ASP A 140 ? 0.13825 0.19016 0.12206 -0.01903 -0.00648 -0.02820 163 ASP A CA  
2152 C  C   A ASP A 140 ? 0.10781 0.16267 0.11406 -0.02130 0.01112  -0.01654 163 ASP A C   
2153 C  C   B ASP A 140 ? 0.13089 0.17470 0.11231 -0.00901 -0.00065 -0.01978 163 ASP A C   
2154 O  O   A ASP A 140 ? 0.10760 0.15819 0.12570 -0.01391 -0.00051 -0.04185 163 ASP A O   
2155 O  O   B ASP A 140 ? 0.14717 0.18543 0.11324 0.00507  -0.00808 -0.02721 163 ASP A O   
2156 C  CB  A ASP A 140 ? 0.11809 0.16508 0.11381 -0.00623 0.00477  -0.00873 163 ASP A CB  
2157 C  CB  B ASP A 140 ? 0.16041 0.21964 0.13526 -0.01313 -0.02328 -0.03761 163 ASP A CB  
2158 C  CG  A ASP A 140 ? 0.11202 0.15914 0.10490 0.00464  0.00179  -0.00360 163 ASP A CG  
2159 C  CG  B ASP A 140 ? 0.17029 0.24589 0.14270 -0.00088 -0.04332 -0.05422 163 ASP A CG  
2160 O  OD1 A ASP A 140 ? 0.15748 0.20563 0.11213 0.02502  -0.00494 -0.03377 163 ASP A OD1 
2161 O  OD1 B ASP A 140 ? 0.16092 0.24681 0.14193 -0.00460 -0.02301 -0.04439 163 ASP A OD1 
2162 O  OD2 A ASP A 140 ? 0.15156 0.14947 0.09404 0.01953  0.02035  -0.01453 163 ASP A OD2 
2163 O  OD2 B ASP A 140 ? 0.20261 0.25611 0.15232 0.01523  -0.04478 -0.07890 163 ASP A OD2 
2172 N  N   . ARG A 141 ? 0.10936 0.15104 0.10382 -0.00449 0.01722  -0.01540 164 ARG A N   
2173 C  CA  . ARG A 141 ? 0.11841 0.14910 0.10074 -0.01488 0.01285  -0.02126 164 ARG A CA  
2174 C  C   . ARG A 141 ? 0.12280 0.14080 0.10373 -0.02712 0.01840  -0.01143 164 ARG A C   
2175 O  O   . ARG A 141 ? 0.12358 0.15635 0.11049 -0.02430 0.01671  -0.01339 164 ARG A O   
2176 C  CB  . ARG A 141 ? 0.12059 0.15649 0.11466 -0.01633 0.01930  -0.01037 164 ARG A CB  
2177 C  CG  . ARG A 141 ? 0.12523 0.14419 0.11931 -0.02510 0.01972  -0.02761 164 ARG A CG  
2178 C  CD  . ARG A 141 ? 0.13212 0.15262 0.10975 -0.01966 0.02859  -0.02744 164 ARG A CD  
2179 N  NE  . ARG A 141 ? 0.14234 0.15512 0.11325 -0.02792 0.01745  -0.01628 164 ARG A NE  
2180 C  CZ  . ARG A 141 ? 0.11442 0.14845 0.11076 -0.00818 0.01787  -0.00823 164 ARG A CZ  
2181 N  NH1 . ARG A 141 ? 0.13361 0.16946 0.10458 -0.02377 0.02951  -0.00807 164 ARG A NH1 
2182 N  NH2 . ARG A 141 ? 0.13868 0.16250 0.12043 -0.01097 0.03326  -0.02125 164 ARG A NH2 
2196 N  N   . THR A 142 ? 0.11765 0.14485 0.11877 -0.01284 0.01731  -0.02210 165 THR A N   
2197 C  CA  . THR A 142 ? 0.12062 0.15264 0.11817 -0.02329 0.02122  -0.02124 165 THR A CA  
2198 C  C   . THR A 142 ? 0.10601 0.12297 0.11023 -0.01059 0.02142  -0.01126 165 THR A C   
2199 O  O   . THR A 142 ? 0.11382 0.15970 0.10589 -0.01567 0.02391  -0.00741 165 THR A O   
2200 C  CB  . THR A 142 ? 0.13441 0.16478 0.11955 -0.00773 0.02834  -0.02871 165 THR A CB  
2201 O  OG1 . THR A 142 ? 0.17189 0.15573 0.13515 -0.00362 0.02967  -0.01903 165 THR A OG1 
2202 C  CG2 . THR A 142 ? 0.17672 0.18758 0.10950 -0.03163 0.03254  -0.03804 165 THR A CG2 
2210 N  N   . GLU A 143 ? 0.10700 0.14426 0.11379 -0.01523 0.00424  -0.01525 166 GLU A N   
2211 C  CA  . GLU A 143 ? 0.11738 0.15266 0.12498 -0.02007 0.00198  -0.00881 166 GLU A CA  
2212 C  C   . GLU A 143 ? 0.12254 0.14067 0.13428 -0.00618 0.01955  -0.00289 166 GLU A C   
2213 O  O   . GLU A 143 ? 0.15125 0.15150 0.13329 -0.00707 0.01609  -0.01272 166 GLU A O   
2214 C  CB  . GLU A 143 ? 0.11303 0.15432 0.12342 -0.01591 0.01222  -0.01411 166 GLU A CB  
2215 C  CG  . GLU A 143 ? 0.10171 0.15018 0.12193 0.00241  0.02020  -0.02265 166 GLU A CG  
2216 C  CD  . GLU A 143 ? 0.11928 0.14991 0.12275 -0.02149 0.01186  -0.01391 166 GLU A CD  
2217 O  OE1 . GLU A 143 ? 0.13313 0.15910 0.13503 -0.01965 0.01325  -0.01326 166 GLU A OE1 
2218 O  OE2 . GLU A 143 ? 0.12277 0.14110 0.12669 -0.02004 0.00942  -0.00380 166 GLU A OE2 
2225 N  N   . PRO A 144 ? 0.13533 0.16273 0.14386 -0.01736 0.02084  0.00758  167 PRO A N   
2226 C  CA  . PRO A 144 ? 0.16907 0.18360 0.13535 -0.02622 0.02561  0.00069  167 PRO A CA  
2227 C  C   . PRO A 144 ? 0.15882 0.15104 0.12858 -0.03535 0.01978  -0.01379 167 PRO A C   
2228 O  O   . PRO A 144 ? 0.17119 0.16853 0.12139 -0.03203 0.01611  -0.02662 167 PRO A O   
2229 C  CB  . PRO A 144 ? 0.19283 0.24666 0.13005 -0.00261 0.02253  -0.00171 167 PRO A CB  
2230 C  CG  . PRO A 144 ? 0.20918 0.22655 0.15334 0.01988  0.03435  0.02869  167 PRO A CG  
2231 C  CD  . PRO A 144 ? 0.16819 0.16165 0.15598 -0.00370 0.03557  0.01011  167 PRO A CD  
2239 N  N   . THR A 145 ? 0.14173 0.13787 0.12770 -0.01957 0.02566  -0.01377 168 THR A N   
2240 C  CA  . THR A 145 ? 0.12050 0.15916 0.11836 -0.02596 0.02798  -0.00449 168 THR A CA  
2241 C  C   . THR A 145 ? 0.13220 0.14319 0.11247 -0.02505 0.02532  0.00175  168 THR A C   
2242 O  O   . THR A 145 ? 0.13648 0.17049 0.11110 -0.01591 0.03210  0.00120  168 THR A O   
2243 C  CB  . THR A 145 ? 0.15492 0.15097 0.13644 -0.03721 0.01721  -0.00463 168 THR A CB  
2244 O  OG1 . THR A 145 ? 0.16383 0.15547 0.13557 -0.03175 0.01761  -0.01151 168 THR A OG1 
2245 C  CG2 . THR A 145 ? 0.20495 0.19009 0.14857 -0.04414 0.01802  0.00408  168 THR A CG2 
2253 N  N   . LEU A 146 ? 0.13642 0.13685 0.11635 -0.01036 0.03122  -0.01070 169 LEU A N   
2254 C  CA  . LEU A 146 ? 0.14538 0.12706 0.10810 -0.01355 0.02788  -0.00642 169 LEU A CA  
2255 C  C   . LEU A 146 ? 0.14084 0.14189 0.10514 -0.00447 0.02961  -0.01797 169 LEU A C   
2256 O  O   . LEU A 146 ? 0.14913 0.13479 0.11767 -0.00250 0.04240  -0.01758 169 LEU A O   
2257 C  CB  . LEU A 146 ? 0.12821 0.13256 0.09890 -0.00363 0.01839  -0.00298 169 LEU A CB  
2258 C  CG  . LEU A 146 ? 0.12265 0.14228 0.10881 -0.01587 0.01854  -0.00146 169 LEU A CG  
2259 C  CD1 . LEU A 146 ? 0.16260 0.17263 0.12208 -0.03748 0.01116  -0.03660 169 LEU A CD1 
2260 C  CD2 . LEU A 146 ? 0.12208 0.16615 0.10402 -0.02958 0.02677  -0.00980 169 LEU A CD2 
2272 N  N   A ASN A 147 ? 0.15179 0.14283 0.09479 -0.02143 0.02789  -0.00883 170 ASN A N   
2273 N  N   B ASN A 147 ? 0.14478 0.14706 0.10187 -0.01702 0.02766  -0.01231 170 ASN A N   
2274 C  CA  A ASN A 147 ? 0.17064 0.16457 0.09512 -0.01759 0.03487  -0.01339 170 ASN A CA  
2275 C  CA  B ASN A 147 ? 0.15616 0.15445 0.10451 -0.02289 0.02620  -0.01109 170 ASN A CA  
2276 C  C   A ASN A 147 ? 0.17581 0.13493 0.10107 -0.02120 0.03990  -0.01069 170 ASN A C   
2277 C  C   B ASN A 147 ? 0.16260 0.15011 0.10165 -0.02501 0.02741  -0.00278 170 ASN A C   
2278 O  O   A ASN A 147 ? 0.20950 0.14799 0.09587 -0.01840 0.03618  -0.02494 170 ASN A O   
2279 O  O   B ASN A 147 ? 0.18332 0.17332 0.09510 -0.01811 0.01895  -0.00402 170 ASN A O   
2280 C  CB  A ASN A 147 ? 0.16672 0.19393 0.09929 -0.00798 0.02640  -0.01160 170 ASN A CB  
2281 C  CB  B ASN A 147 ? 0.14410 0.14702 0.11609 -0.00150 0.02415  -0.01118 170 ASN A CB  
2282 C  CG  A ASN A 147 ? 0.15742 0.20442 0.10548 -0.00782 0.03129  -0.00708 170 ASN A CG  
2283 C  CG  B ASN A 147 ? 0.12341 0.16830 0.13167 0.00469  0.03282  0.00574  170 ASN A CG  
2284 O  OD1 A ASN A 147 ? 0.12708 0.17577 0.10438 -0.02345 0.01663  -0.00814 170 ASN A OD1 
2285 O  OD1 B ASN A 147 ? 0.08509 0.14991 0.13607 0.00762  0.02486  0.00137  170 ASN A OD1 
2286 N  ND2 A ASN A 147 ? 0.15455 0.18734 0.10953 -0.01265 0.06069  -0.02096 170 ASN A ND2 
2287 N  ND2 B ASN A 147 ? 0.12236 0.16635 0.14071 -0.02882 0.04879  0.00804  170 ASN A ND2 
2300 N  N   . THR A 148 ? 0.15417 0.16448 0.09753 -0.03420 0.03081  0.00743  171 THR A N   
2301 C  CA  . THR A 148 ? 0.17285 0.15902 0.10976 -0.01300 0.03990  0.01312  171 THR A CA  
2302 C  C   . THR A 148 ? 0.16339 0.16283 0.09900 -0.01553 0.05311  0.00507  171 THR A C   
2303 O  O   . THR A 148 ? 0.16491 0.17361 0.10003 -0.03628 0.04791  0.00366  171 THR A O   
2304 C  CB  . THR A 148 ? 0.18041 0.16532 0.12003 -0.03598 0.04687  -0.01104 171 THR A CB  
2305 O  OG1 . THR A 148 ? 0.17346 0.17027 0.11452 -0.02307 0.04217  -0.01001 171 THR A OG1 
2306 C  CG2 . THR A 148 ? 0.21326 0.16731 0.13458 -0.02371 0.04021  -0.01029 171 THR A CG2 
2314 N  N   . ALA A 149 ? 0.17870 0.16609 0.09488 -0.02157 0.02737  -0.00684 172 ALA A N   
2315 C  CA  . ALA A 149 ? 0.16107 0.16695 0.10195 -0.03070 0.01834  -0.00712 172 ALA A CA  
2316 C  C   . ALA A 149 ? 0.15522 0.19674 0.10209 -0.03267 0.02833  -0.00245 172 ALA A C   
2317 O  O   . ALA A 149 ? 0.18268 0.19562 0.09412 -0.02523 0.04262  -0.01805 172 ALA A O   
2318 C  CB  . ALA A 149 ? 0.18379 0.17332 0.09636 -0.03008 0.01245  -0.00108 172 ALA A CB  
2324 N  N   . ILE A 150 ? 0.16400 0.19705 0.11614 -0.04869 0.03078  -0.01634 173 ILE A N   
2325 C  CA  . ILE A 150 ? 0.17219 0.22417 0.13508 -0.04759 0.04888  0.00035  173 ILE A CA  
2326 C  C   . ILE A 150 ? 0.16575 0.23683 0.13497 -0.04665 0.04262  -0.01466 173 ILE A C   
2327 O  O   . ILE A 150 ? 0.18373 0.19637 0.13148 -0.02749 0.04232  -0.00918 173 ILE A O   
2328 C  CB  . ILE A 150 ? 0.19061 0.22631 0.16398 -0.05166 0.05834  -0.01470 173 ILE A CB  
2329 C  CG1 . ILE A 150 ? 0.22993 0.21947 0.17276 -0.04560 0.06366  -0.02329 173 ILE A CG1 
2330 C  CG2 . ILE A 150 ? 0.21429 0.24970 0.18341 -0.07372 0.07178  -0.01435 173 ILE A CG2 
2331 C  CD1 . ILE A 150 ? 0.26909 0.23158 0.18088 -0.03962 0.05916  -0.02259 173 ILE A CD1 
2343 N  N   . PRO A 151 ? 0.18571 0.24871 0.13415 -0.02953 0.04201  -0.02173 174 PRO A N   
2344 C  CA  . PRO A 151 ? 0.18941 0.26964 0.13784 -0.00058 0.04952  -0.02921 174 PRO A CA  
2345 C  C   . PRO A 151 ? 0.18311 0.28876 0.14421 -0.01895 0.04600  -0.01791 174 PRO A C   
2346 O  O   . PRO A 151 ? 0.18161 0.28802 0.15356 -0.04145 0.04151  -0.00708 174 PRO A O   
2347 C  CB  . PRO A 151 ? 0.21473 0.33750 0.13672 0.04539  0.04149  -0.03161 174 PRO A CB  
2348 C  CG  . PRO A 151 ? 0.25984 0.33983 0.13844 0.03875  0.05308  -0.02576 174 PRO A CG  
2349 C  CD  . PRO A 151 ? 0.22374 0.28018 0.13090 -0.00992 0.06412  -0.01721 174 PRO A CD  
2357 N  N   . GLY A 152 ? 0.18108 0.28843 0.15543 -0.00963 0.03632  -0.01827 175 GLY A N   
2358 C  CA  . GLY A 152 ? 0.19618 0.29888 0.14967 0.01821  0.04100  -0.01661 175 GLY A CA  
2359 C  C   . GLY A 152 ? 0.19116 0.28761 0.14337 0.01252  0.03754  0.00261  175 GLY A C   
2360 O  O   . GLY A 152 ? 0.19117 0.33643 0.16089 0.02360  0.01766  0.00319  175 GLY A O   
2364 N  N   . ASP A 153 ? 0.15575 0.22609 0.13869 0.00059  0.02100  -0.00342 176 ASP A N   
2365 C  CA  . ASP A 153 ? 0.15271 0.21210 0.13836 -0.03021 0.01783  -0.02253 176 ASP A CA  
2366 C  C   . ASP A 153 ? 0.11911 0.23683 0.12874 -0.02401 0.00553  -0.02927 176 ASP A C   
2367 O  O   . ASP A 153 ? 0.13671 0.22193 0.11879 -0.03010 0.00723  -0.00241 176 ASP A O   
2368 C  CB  . ASP A 153 ? 0.14394 0.19239 0.14936 -0.01957 0.01463  -0.00686 176 ASP A CB  
2369 C  CG  . ASP A 153 ? 0.16623 0.20694 0.14769 -0.05041 0.00452  -0.01393 176 ASP A CG  
2370 O  OD1 . ASP A 153 ? 0.18027 0.21407 0.13707 -0.06300 0.02523  -0.02337 176 ASP A OD1 
2371 O  OD2 . ASP A 153 ? 0.22021 0.22274 0.15343 -0.04055 0.00710  -0.03956 176 ASP A OD2 
2376 N  N   . PRO A 154 ? 0.11721 0.24654 0.13359 -0.03231 -0.00040 -0.01702 177 PRO A N   
2377 C  CA  . PRO A 154 ? 0.12507 0.20868 0.12774 -0.00837 -0.00295 -0.01107 177 PRO A CA  
2378 C  C   . PRO A 154 ? 0.10218 0.17543 0.11164 -0.02318 -0.01128 -0.01013 177 PRO A C   
2379 O  O   . PRO A 154 ? 0.13324 0.17503 0.10511 -0.02583 -0.00422 0.00114  177 PRO A O   
2380 C  CB  . PRO A 154 ? 0.13594 0.26125 0.13656 -0.02524 0.00065  0.00569  177 PRO A CB  
2381 C  CG  . PRO A 154 ? 0.14086 0.31581 0.14468 -0.02661 0.00267  0.00269  177 PRO A CG  
2382 C  CD  . PRO A 154 ? 0.13220 0.28981 0.13523 -0.02885 -0.00443 -0.02205 177 PRO A CD  
2390 N  N   . ARG A 155 ? 0.12068 0.18596 0.11963 -0.03905 -0.00812 -0.02019 178 ARG A N   
2391 C  CA  . ARG A 155 ? 0.12168 0.15518 0.10877 -0.02852 0.01506  -0.00821 178 ARG A CA  
2392 C  C   . ARG A 155 ? 0.12541 0.15649 0.08915 -0.01741 0.00574  -0.00454 178 ARG A C   
2393 O  O   . ARG A 155 ? 0.13375 0.16835 0.08295 -0.03900 0.01253  -0.00837 178 ARG A O   
2394 C  CB  . ARG A 155 ? 0.13091 0.15426 0.12702 -0.03218 0.01120  -0.00591 178 ARG A CB  
2395 C  CG  . ARG A 155 ? 0.16035 0.15375 0.13853 -0.04124 -0.00339 -0.00817 178 ARG A CG  
2396 C  CD  . ARG A 155 ? 0.14943 0.18716 0.13897 -0.04169 0.00492  0.00208  178 ARG A CD  
2397 N  NE  . ARG A 155 ? 0.15267 0.17703 0.13996 -0.04615 0.00510  -0.01153 178 ARG A NE  
2398 C  CZ  . ARG A 155 ? 0.16530 0.18965 0.14767 -0.03864 0.00636  -0.01496 178 ARG A CZ  
2399 N  NH1 . ARG A 155 ? 0.17107 0.16160 0.15668 -0.03264 0.02261  -0.01370 178 ARG A NH1 
2400 N  NH2 . ARG A 155 ? 0.19278 0.18425 0.14355 -0.02045 0.03477  -0.00924 178 ARG A NH2 
2414 N  N   . ASP A 156 ? 0.11163 0.15787 0.07955 -0.02366 -0.00227 -0.00688 179 ASP A N   
2415 C  CA  . ASP A 156 ? 0.12023 0.14211 0.08039 -0.01266 -0.00634 -0.01213 179 ASP A CA  
2416 C  C   . ASP A 156 ? 0.11591 0.14472 0.08312 -0.01595 0.00639  -0.00898 179 ASP A C   
2417 O  O   . ASP A 156 ? 0.11538 0.15111 0.09355 -0.00366 -0.00495 -0.01201 179 ASP A O   
2418 C  CB  . ASP A 156 ? 0.11393 0.14559 0.08440 -0.01623 0.00960  -0.02145 179 ASP A CB  
2419 C  CG  . ASP A 156 ? 0.11340 0.14499 0.10161 -0.00621 0.02314  -0.01181 179 ASP A CG  
2420 O  OD1 . ASP A 156 ? 0.13595 0.14873 0.09718 -0.00998 0.02332  -0.01332 179 ASP A OD1 
2421 O  OD2 . ASP A 156 ? 0.13362 0.15723 0.10799 -0.01856 0.01772  -0.00676 179 ASP A OD2 
2426 N  N   . THR A 157 ? 0.10666 0.15168 0.08935 -0.01633 -0.00320 -0.01415 180 THR A N   
2427 C  CA  . THR A 157 ? 0.09741 0.16114 0.09052 -0.01926 0.00338  -0.00614 180 THR A CA  
2428 C  C   . THR A 157 ? 0.10985 0.15043 0.08525 -0.00231 0.00233  -0.01471 180 THR A C   
2429 O  O   . THR A 157 ? 0.12044 0.14589 0.08801 -0.01319 0.00656  -0.01839 180 THR A O   
2430 C  CB  . THR A 157 ? 0.10472 0.15174 0.10657 -0.01024 0.01302  -0.01661 180 THR A CB  
2431 O  OG1 . THR A 157 ? 0.10984 0.16569 0.11526 -0.00758 0.00000  -0.00169 180 THR A OG1 
2432 C  CG2 . THR A 157 ? 0.09664 0.17206 0.11148 -0.03035 0.02002  -0.00563 180 THR A CG2 
2440 N  N   . THR A 158 ? 0.13077 0.14755 0.07779 -0.01124 0.00308  -0.00972 181 THR A N   
2441 C  CA  . THR A 158 ? 0.11951 0.15118 0.08317 0.00859  0.00801  -0.01096 181 THR A CA  
2442 C  C   . THR A 158 ? 0.11667 0.15504 0.09260 -0.01799 0.00545  -0.01865 181 THR A C   
2443 O  O   . THR A 158 ? 0.14936 0.15436 0.08534 -0.00312 0.02475  -0.00499 181 THR A O   
2444 C  CB  . THR A 158 ? 0.12497 0.13519 0.07862 -0.00351 0.01092  -0.00332 181 THR A CB  
2445 O  OG1 . THR A 158 ? 0.10576 0.15267 0.08826 -0.01006 -0.00048 0.00312  181 THR A OG1 
2446 C  CG2 . THR A 158 ? 0.12567 0.15129 0.08808 -0.00297 -0.00349 0.01201  181 THR A CG2 
2454 N  N   . SER A 159 ? 0.12026 0.15560 0.08965 -0.00325 0.01754  -0.00119 182 SER A N   
2455 C  CA  . SER A 159 ? 0.11498 0.16004 0.09654 -0.01699 0.00845  -0.00561 182 SER A CA  
2456 C  C   . SER A 159 ? 0.12518 0.15390 0.08906 0.00598  0.01643  -0.00149 182 SER A C   
2457 O  O   . SER A 159 ? 0.12603 0.14388 0.09858 -0.00606 0.03137  -0.01039 182 SER A O   
2458 C  CB  . SER A 159 ? 0.13241 0.15254 0.10514 0.00529  0.02335  -0.00163 182 SER A CB  
2459 O  OG  . SER A 159 ? 0.13152 0.16544 0.13155 0.01405  -0.00086 0.01109  182 SER A OG  
2465 N  N   . PRO A 160 ? 0.12579 0.14955 0.08198 -0.01614 0.01469  -0.01187 183 PRO A N   
2466 C  CA  . PRO A 160 ? 0.13470 0.15771 0.08536 0.01939  0.01047  0.00290  183 PRO A CA  
2467 C  C   . PRO A 160 ? 0.13766 0.15119 0.08531 -0.00412 0.01490  -0.01468 183 PRO A C   
2468 O  O   . PRO A 160 ? 0.13988 0.17021 0.07534 -0.02458 0.01068  -0.00796 183 PRO A O   
2469 C  CB  . PRO A 160 ? 0.14289 0.14856 0.09989 -0.01082 0.01588  0.00166  183 PRO A CB  
2470 C  CG  . PRO A 160 ? 0.13113 0.16851 0.09151 -0.00074 0.02027  -0.00314 183 PRO A CG  
2471 C  CD  . PRO A 160 ? 0.14237 0.15075 0.08341 -0.00247 0.02443  -0.00328 183 PRO A CD  
2479 N  N   . ARG A 161 ? 0.14507 0.15644 0.10417 -0.00125 0.00601  0.00065  184 ARG A N   
2480 C  CA  . ARG A 161 ? 0.17937 0.13539 0.10920 0.00017  0.01001  0.00638  184 ARG A CA  
2481 C  C   . ARG A 161 ? 0.14186 0.15758 0.10424 -0.00797 0.01016  0.00624  184 ARG A C   
2482 O  O   . ARG A 161 ? 0.12617 0.16764 0.09825 -0.02045 -0.00746 0.00605  184 ARG A O   
2483 C  CB  . ARG A 161 ? 0.20468 0.16782 0.13043 0.04606  0.02585  0.02501  184 ARG A CB  
2484 C  CG  . ARG A 161 ? 0.23239 0.19948 0.15095 0.06622  0.02636  0.03887  184 ARG A CG  
2485 C  CD  . ARG A 161 ? 0.25980 0.22053 0.16787 0.06693  0.02765  0.03952  184 ARG A CD  
2486 N  NE  . ARG A 161 ? 0.29312 0.20321 0.19099 0.04705  0.02244  0.02965  184 ARG A NE  
2487 C  CZ  . ARG A 161 ? 0.29397 0.22737 0.20907 0.04585  0.02117  0.01445  184 ARG A CZ  
2488 N  NH1 . ARG A 161 ? 0.33719 0.26124 0.21794 0.05610  0.02822  0.01363  184 ARG A NH1 
2489 N  NH2 . ARG A 161 ? 0.27253 0.21893 0.21911 0.02259  0.02525  -0.00737 184 ARG A NH2 
2503 N  N   . ALA A 162 ? 0.13425 0.15527 0.09967 -0.01576 0.01474  -0.00219 185 ALA A N   
2504 C  CA  . ALA A 162 ? 0.11758 0.17834 0.09959 -0.02683 0.00254  -0.00303 185 ALA A CA  
2505 C  C   . ALA A 162 ? 0.13224 0.14765 0.09460 -0.01949 0.00834  -0.01022 185 ALA A C   
2506 O  O   . ALA A 162 ? 0.11467 0.17057 0.09624 -0.00340 0.00849  0.00113  185 ALA A O   
2507 C  CB  . ALA A 162 ? 0.11624 0.20029 0.11169 -0.01556 0.00448  -0.01758 185 ALA A CB  
2513 N  N   . MET A 163 ? 0.12455 0.15834 0.08670 -0.01447 0.01141  0.00142  186 MET A N   
2514 C  CA  . MET A 163 ? 0.12101 0.13886 0.08663 -0.01533 0.00323  -0.00098 186 MET A CA  
2515 C  C   . MET A 163 ? 0.12390 0.14385 0.07162 -0.01089 -0.01014 -0.00252 186 MET A C   
2516 O  O   . MET A 163 ? 0.12327 0.16648 0.07908 -0.01203 0.00372  0.01189  186 MET A O   
2517 C  CB  . MET A 163 ? 0.12906 0.14436 0.09445 -0.02091 -0.00330 -0.00892 186 MET A CB  
2518 C  CG  . MET A 163 ? 0.12785 0.16428 0.08764 -0.00158 -0.00760 0.00370  186 MET A CG  
2519 S  SD  . MET A 163 ? 0.14743 0.17631 0.09923 0.01016  -0.00517 -0.00067 186 MET A SD  
2520 C  CE  . MET A 163 ? 0.21396 0.22741 0.11004 0.01166  -0.00512 -0.02683 186 MET A CE  
2530 N  N   . ALA A 164 ? 0.13358 0.14071 0.07572 -0.01852 -0.00232 -0.00448 187 ALA A N   
2531 C  CA  . ALA A 164 ? 0.12707 0.12962 0.08131 -0.00461 0.00484  0.00762  187 ALA A CA  
2532 C  C   . ALA A 164 ? 0.12431 0.14053 0.07145 -0.01093 -0.01211 -0.00112 187 ALA A C   
2533 O  O   . ALA A 164 ? 0.11846 0.15813 0.08286 -0.03320 -0.00001 0.00611  187 ALA A O   
2534 C  CB  . ALA A 164 ? 0.15250 0.13021 0.07726 -0.01440 0.00281  0.01678  187 ALA A CB  
2541 N  N   . GLN A 165 ? 0.12409 0.16167 0.06798 -0.01561 -0.00847 0.00118  188 GLN A N   
2542 C  CA  . GLN A 165 ? 0.12959 0.17169 0.06866 -0.01553 -0.01159 0.01903  188 GLN A CA  
2543 C  C   . GLN A 165 ? 0.13558 0.15060 0.06958 -0.00164 -0.00915 0.00836  188 GLN A C   
2544 O  O   . GLN A 165 ? 0.14509 0.16909 0.07101 -0.01844 0.00752  0.01572  188 GLN A O   
2545 C  CB  . GLN A 165 ? 0.13994 0.19055 0.09441 0.00613  -0.00505 0.01679  188 GLN A CB  
2546 C  CG  . GLN A 165 ? 0.14045 0.19406 0.12456 0.00252  0.00311  0.01976  188 GLN A CG  
2547 C  CD  . GLN A 165 ? 0.17766 0.21066 0.14552 -0.00432 0.00788  0.00150  188 GLN A CD  
2548 O  OE1 . GLN A 165 ? 0.21936 0.22167 0.15124 -0.03175 -0.00065 0.00308  188 GLN A OE1 
2549 N  NE2 . GLN A 165 ? 0.24451 0.20539 0.18313 -0.00882 0.01539  -0.00820 188 GLN A NE2 
2558 N  N   . THR A 166 ? 0.13889 0.14890 0.07572 -0.00365 0.00191  0.01696  189 THR A N   
2559 C  CA  . THR A 166 ? 0.13232 0.14372 0.08977 -0.01555 0.00063  0.00746  189 THR A CA  
2560 C  C   . THR A 166 ? 0.11496 0.15686 0.08580 -0.02706 0.00812  0.01176  189 THR A C   
2561 O  O   . THR A 166 ? 0.12565 0.14953 0.09138 -0.01953 0.00077  0.00274  189 THR A O   
2562 C  CB  . THR A 166 ? 0.12683 0.16220 0.11280 -0.00373 -0.00495 -0.00202 189 THR A CB  
2563 O  OG1 . THR A 166 ? 0.13834 0.16735 0.09448 -0.02882 -0.00378 0.00005  189 THR A OG1 
2564 C  CG2 . THR A 166 ? 0.16553 0.15217 0.14650 -0.01298 0.00375  -0.02378 189 THR A CG2 
2572 N  N   . LEU A 167 ? 0.13708 0.17066 0.07895 -0.02422 -0.01511 0.01956  190 LEU A N   
2573 C  CA  . LEU A 167 ? 0.13376 0.15589 0.08773 -0.02381 0.00156  0.00959  190 LEU A CA  
2574 C  C   . LEU A 167 ? 0.13040 0.16784 0.08353 -0.00920 0.00597  0.00360  190 LEU A C   
2575 O  O   . LEU A 167 ? 0.11089 0.20900 0.09106 -0.03489 0.01251  0.01232  190 LEU A O   
2576 C  CB  . LEU A 167 ? 0.11371 0.15743 0.07917 -0.00902 0.00575  0.00753  190 LEU A CB  
2577 C  CG  . LEU A 167 ? 0.11587 0.15328 0.09190 -0.00857 -0.00162 -0.00591 190 LEU A CG  
2578 C  CD1 . LEU A 167 ? 0.15850 0.17531 0.10579 0.01639  0.00037  -0.01438 190 LEU A CD1 
2579 C  CD2 . LEU A 167 ? 0.13692 0.16169 0.07497 0.00084  -0.00995 0.00347  190 LEU A CD2 
2591 N  N   A ARG A 168 ? 0.13646 0.17121 0.09077 -0.02692 0.00077  0.01193  191 ARG A N   
2592 N  N   B ARG A 168 ? 0.14618 0.18337 0.09079 -0.01758 -0.00071 0.01001  191 ARG A N   
2593 C  CA  A ARG A 168 ? 0.15464 0.16081 0.08761 -0.03204 0.01190  0.00676  191 ARG A CA  
2594 C  CA  B ARG A 168 ? 0.17227 0.19659 0.09364 -0.01961 -0.00149 0.00974  191 ARG A CA  
2595 C  C   A ARG A 168 ? 0.16363 0.16269 0.09524 -0.02067 0.01144  0.01339  191 ARG A C   
2596 C  C   B ARG A 168 ? 0.16432 0.17215 0.09696 -0.02075 0.00483  0.01471  191 ARG A C   
2597 O  O   A ARG A 168 ? 0.16097 0.17096 0.10962 -0.03560 0.02092  0.01455  191 ARG A O   
2598 O  O   B ARG A 168 ? 0.16116 0.16017 0.10415 -0.03552 0.00669  0.01484  191 ARG A O   
2599 C  CB  A ARG A 168 ? 0.19541 0.14539 0.08905 -0.02196 0.03995  -0.00527 191 ARG A CB  
2600 C  CB  B ARG A 168 ? 0.21913 0.23316 0.09853 -0.01564 -0.00558 0.00279  191 ARG A CB  
2601 C  CG  A ARG A 168 ? 0.21407 0.15601 0.10486 -0.02068 -0.00118 0.00105  191 ARG A CG  
2602 C  CG  B ARG A 168 ? 0.26354 0.28488 0.10850 -0.00976 -0.02685 -0.00049 191 ARG A CG  
2603 C  CD  A ARG A 168 ? 0.25303 0.22731 0.13185 -0.07568 -0.01241 0.01901  191 ARG A CD  
2604 C  CD  B ARG A 168 ? 0.28577 0.31406 0.11582 -0.01532 -0.04894 -0.01427 191 ARG A CD  
2605 N  NE  A ARG A 168 ? 0.22661 0.26643 0.15469 -0.07664 -0.05084 0.05952  191 ARG A NE  
2606 N  NE  B ARG A 168 ? 0.30953 0.32285 0.11699 -0.00211 -0.04005 -0.03544 191 ARG A NE  
2607 C  CZ  A ARG A 168 ? 0.28646 0.24242 0.15101 -0.09665 -0.08568 0.04972  191 ARG A CZ  
2608 C  CZ  B ARG A 168 ? 0.34553 0.29920 0.11627 -0.03146 -0.03726 -0.02858 191 ARG A CZ  
2609 N  NH1 A ARG A 168 ? 0.33015 0.21888 0.16612 -0.09176 -0.09591 0.07345  191 ARG A NH1 
2610 N  NH1 B ARG A 168 ? 0.36688 0.30586 0.12050 -0.06440 -0.02925 -0.02265 191 ARG A NH1 
2611 N  NH2 A ARG A 168 ? 0.31619 0.22649 0.14154 -0.07184 -0.06524 0.05807  191 ARG A NH2 
2612 N  NH2 B ARG A 168 ? 0.32608 0.21811 0.10246 -0.00590 -0.03314 -0.03398 191 ARG A NH2 
2639 N  N   . ASN A 169 ? 0.14656 0.16048 0.09665 -0.01415 0.01273  0.01834  192 ASN A N   
2640 C  CA  . ASN A 169 ? 0.14851 0.16599 0.09148 -0.02044 0.01370  0.00089  192 ASN A CA  
2641 C  C   . ASN A 169 ? 0.14648 0.14890 0.10088 -0.03047 0.01596  0.00283  192 ASN A C   
2642 O  O   . ASN A 169 ? 0.17546 0.15928 0.13386 -0.01883 0.04888  0.01508  192 ASN A O   
2643 C  CB  . ASN A 169 ? 0.14931 0.17179 0.09949 0.01978  0.00414  0.01132  192 ASN A CB  
2644 C  CG  . ASN A 169 ? 0.20490 0.21955 0.11594 0.06075  0.00747  -0.00924 192 ASN A CG  
2645 O  OD1 . ASN A 169 ? 0.26014 0.22119 0.11976 0.04358  0.00967  0.01856  192 ASN A OD1 
2646 N  ND2 . ASN A 169 ? 0.25209 0.22702 0.12680 0.03776  -0.01574 -0.01759 192 ASN A ND2 
2654 N  N   . LEU A 170 ? 0.11811 0.15376 0.10358 -0.01134 0.01246  0.02082  193 LEU A N   
2655 C  CA  . LEU A 170 ? 0.10934 0.15844 0.12605 -0.01904 0.01215  0.00981  193 LEU A CA  
2656 C  C   . LEU A 170 ? 0.11602 0.16967 0.14106 -0.03144 0.01396  0.01453  193 LEU A C   
2657 O  O   . LEU A 170 ? 0.10912 0.19523 0.14366 -0.01544 0.01385  0.02108  193 LEU A O   
2658 C  CB  . LEU A 170 ? 0.11213 0.15612 0.14056 -0.01119 -0.00167 0.00680  193 LEU A CB  
2659 C  CG  . LEU A 170 ? 0.11418 0.15654 0.16280 -0.01150 0.02068  -0.00845 193 LEU A CG  
2660 C  CD1 . LEU A 170 ? 0.13931 0.16732 0.17972 -0.01796 0.04853  -0.00834 193 LEU A CD1 
2661 C  CD2 . LEU A 170 ? 0.15907 0.15657 0.16891 -0.02017 0.00698  -0.02374 193 LEU A CD2 
2673 N  N   . THR A 171 ? 0.11642 0.17004 0.15669 -0.02241 0.00029  -0.00157 194 THR A N   
2674 C  CA  . THR A 171 ? 0.13772 0.17474 0.15958 -0.03618 -0.00228 -0.00500 194 THR A CA  
2675 C  C   . THR A 171 ? 0.13008 0.21757 0.17123 -0.05594 0.00434  -0.00238 194 THR A C   
2676 O  O   . THR A 171 ? 0.17907 0.24783 0.22483 -0.05289 0.00210  0.00199  194 THR A O   
2677 C  CB  . THR A 171 ? 0.15322 0.19195 0.16058 -0.05066 -0.00002 -0.01583 194 THR A CB  
2678 O  OG1 . THR A 171 ? 0.15355 0.18408 0.14751 -0.04204 -0.00446 -0.00594 194 THR A OG1 
2679 C  CG2 . THR A 171 ? 0.16901 0.19290 0.17262 -0.04179 0.01119  -0.00737 194 THR A CG2 
2687 N  N   . LEU A 172 ? 0.15191 0.19006 0.13906 -0.05027 -0.02233 0.00986  195 LEU A N   
2688 C  CA  . LEU A 172 ? 0.19022 0.18702 0.13731 -0.05951 -0.00844 0.01769  195 LEU A CA  
2689 C  C   . LEU A 172 ? 0.21228 0.19249 0.14288 -0.07885 -0.01271 0.03042  195 LEU A C   
2690 O  O   . LEU A 172 ? 0.27696 0.21236 0.16225 -0.10082 -0.04327 0.04697  195 LEU A O   
2691 C  CB  . LEU A 172 ? 0.21740 0.18979 0.13262 -0.06253 -0.01496 0.01416  195 LEU A CB  
2692 C  CG  . LEU A 172 ? 0.25084 0.20253 0.13468 -0.06335 -0.04323 0.00528  195 LEU A CG  
2693 C  CD1 . LEU A 172 ? 0.27809 0.24311 0.13911 -0.05522 -0.04817 -0.00387 195 LEU A CD1 
2694 C  CD2 . LEU A 172 ? 0.25270 0.23505 0.14409 -0.05640 -0.04265 0.00085  195 LEU A CD2 
2706 N  N   . GLY A 173 ? 0.15970 0.17607 0.12835 -0.03604 0.00851  0.01196  196 GLY A N   
2707 C  CA  . GLY A 173 ? 0.14184 0.16706 0.12526 -0.01430 0.01003  0.02107  196 GLY A CA  
2708 C  C   . GLY A 173 ? 0.13984 0.15739 0.14047 -0.00181 -0.01141 0.00480  196 GLY A C   
2709 O  O   . GLY A 173 ? 0.14812 0.17870 0.16007 -0.01294 -0.00756 0.01834  196 GLY A O   
2713 N  N   . LYS A 174 ? 0.14734 0.16447 0.14119 0.00797  -0.02943 -0.00315 197 LYS A N   
2714 C  CA  . LYS A 174 ? 0.19056 0.16582 0.14007 -0.00643 0.00852  0.00596  197 LYS A CA  
2715 C  C   . LYS A 174 ? 0.15468 0.17605 0.13142 0.00338  -0.00037 -0.00153 197 LYS A C   
2716 O  O   . LYS A 174 ? 0.18543 0.21036 0.12453 0.02411  -0.00731 -0.01252 197 LYS A O   
2717 C  CB  . LYS A 174 ? 0.28596 0.17320 0.16800 -0.03180 0.03080  -0.00280 197 LYS A CB  
2718 C  CG  . LYS A 174 ? 0.36723 0.20060 0.18162 -0.05712 0.04700  0.00865  197 LYS A CG  
2719 C  CD  . LYS A 174 ? 0.43710 0.27624 0.20379 -0.08782 0.03527  0.00802  197 LYS A CD  
2720 C  CE  . LYS A 174 ? 0.50796 0.33259 0.22473 -0.12108 0.03370  0.01965  197 LYS A CE  
2721 N  NZ  . LYS A 174 ? 0.55974 0.38987 0.23760 -0.13532 0.02762  0.01140  197 LYS A NZ  
2735 N  N   . ALA A 175 ? 0.11254 0.17106 0.12405 -0.00163 0.00443  -0.01708 198 ALA A N   
2736 C  CA  . ALA A 175 ? 0.12932 0.17516 0.13994 -0.00230 -0.00536 -0.01924 198 ALA A CA  
2737 C  C   . ALA A 175 ? 0.13284 0.16064 0.11714 0.00309  -0.00376 -0.01712 198 ALA A C   
2738 O  O   . ALA A 175 ? 0.14695 0.19238 0.12811 0.01318  -0.01108 -0.01739 198 ALA A O   
2739 C  CB  . ALA A 175 ? 0.15062 0.20945 0.16134 -0.02973 0.02172  -0.02547 198 ALA A CB  
2745 N  N   . LEU A 176 ? 0.11315 0.17100 0.10160 0.00509  0.01168  0.00712  199 LEU A N   
2746 C  CA  . LEU A 176 ? 0.13137 0.18798 0.11536 0.00947  0.02328  0.01664  199 LEU A CA  
2747 C  C   . LEU A 176 ? 0.15263 0.18220 0.13054 0.01097  0.01596  0.02404  199 LEU A C   
2748 O  O   . LEU A 176 ? 0.16093 0.17086 0.14113 -0.00612 0.02750  0.02459  199 LEU A O   
2749 C  CB  . LEU A 176 ? 0.13076 0.17533 0.13333 0.01032  0.00913  0.01461  199 LEU A CB  
2750 C  CG  . LEU A 176 ? 0.13990 0.16169 0.12251 0.01157  0.00841  0.01254  199 LEU A CG  
2751 C  CD1 . LEU A 176 ? 0.13720 0.19018 0.12305 0.01413  0.01531  0.01437  199 LEU A CD1 
2752 C  CD2 . LEU A 176 ? 0.20536 0.17390 0.12813 0.00205  0.00070  0.00027  199 LEU A CD2 
2764 N  N   . GLY A 177 ? 0.14678 0.21410 0.14247 -0.00425 0.04433  0.02246  200 GLY A N   
2765 C  CA  . GLY A 177 ? 0.17916 0.22821 0.17414 0.00526  0.05508  0.03339  200 GLY A CA  
2766 C  C   . GLY A 177 ? 0.14527 0.21073 0.20219 -0.01968 0.05361  0.03038  200 GLY A C   
2767 O  O   . GLY A 177 ? 0.13819 0.23077 0.19810 -0.03765 0.04013  0.02075  200 GLY A O   
2771 N  N   . ASP A 178 ? 0.17187 0.25342 0.23617 -0.00667 0.04515  0.04126  201 ASP A N   
2772 C  CA  . ASP A 178 ? 0.18140 0.23743 0.27221 -0.01598 0.04527  0.03083  201 ASP A CA  
2773 C  C   . ASP A 178 ? 0.15887 0.20589 0.24813 -0.04195 0.05342  0.00886  201 ASP A C   
2774 O  O   . ASP A 178 ? 0.15311 0.26268 0.25872 -0.03740 0.08214  -0.00858 201 ASP A O   
2775 C  CB  . ASP A 178 ? 0.30353 0.32963 0.31855 -0.04045 0.02632  0.04856  201 ASP A CB  
2776 C  CG  . ASP A 178 ? 0.41357 0.43961 0.35145 -0.07324 0.02372  0.04323  201 ASP A CG  
2777 O  OD1 . ASP A 178 ? 0.48249 0.51382 0.36495 -0.07139 0.02189  0.02720  201 ASP A OD1 
2778 O  OD2 . ASP A 178 ? 0.42381 0.45995 0.37075 -0.10977 0.01925  0.05851  201 ASP A OD2 
2783 N  N   A SER A 179 ? 0.15368 0.22769 0.23570 -0.02366 0.04715  0.00734  202 SER A N   
2784 N  N   B SER A 179 ? 0.15230 0.22377 0.23404 -0.02688 0.04268  -0.00056 202 SER A N   
2785 C  CA  A SER A 179 ? 0.15039 0.22705 0.21307 -0.01138 0.05261  0.01190  202 SER A CA  
2786 C  CA  B SER A 179 ? 0.15193 0.22369 0.21331 -0.02080 0.03930  -0.00650 202 SER A CA  
2787 C  C   A SER A 179 ? 0.14088 0.24071 0.19626 -0.01853 0.04717  0.00532  202 SER A C   
2788 C  C   B SER A 179 ? 0.14935 0.22301 0.20058 -0.01641 0.03120  -0.00785 202 SER A C   
2789 O  O   A SER A 179 ? 0.10299 0.25786 0.18890 -0.01157 0.06713  0.01174  202 SER A O   
2790 O  O   B SER A 179 ? 0.14922 0.22864 0.19794 -0.00370 0.02712  -0.00789 202 SER A O   
2791 C  CB  A SER A 179 ? 0.15489 0.22477 0.21247 -0.00592 0.05647  0.00905  202 SER A CB  
2792 C  CB  B SER A 179 ? 0.15505 0.22775 0.20911 -0.03629 0.03895  -0.01792 202 SER A CB  
2793 O  OG  A SER A 179 ? 0.15277 0.16773 0.20218 0.00785  0.06353  0.02546  202 SER A OG  
2794 O  OG  B SER A 179 ? 0.14101 0.20002 0.20378 -0.05264 0.02903  -0.01354 202 SER A OG  
2805 N  N   . GLN A 180 ? 0.13052 0.22502 0.18957 -0.01295 0.04070  0.00515  203 GLN A N   
2806 C  CA  . GLN A 180 ? 0.12415 0.21405 0.17975 -0.01316 0.04374  0.00563  203 GLN A CA  
2807 C  C   . GLN A 180 ? 0.11048 0.18878 0.18481 -0.01801 0.05310  -0.00215 203 GLN A C   
2808 O  O   . GLN A 180 ? 0.10683 0.19537 0.18677 -0.02613 0.03844  -0.01357 203 GLN A O   
2809 C  CB  . GLN A 180 ? 0.13561 0.20969 0.17682 0.00374  0.04007  0.00402  203 GLN A CB  
2810 C  CG  . GLN A 180 ? 0.15842 0.22067 0.17333 0.01181  0.04845  -0.00691 203 GLN A CG  
2811 C  CD  . GLN A 180 ? 0.17250 0.28294 0.18246 0.03226  0.05000  -0.00270 203 GLN A CD  
2812 O  OE1 . GLN A 180 ? 0.19640 0.28099 0.18057 -0.01148 0.04730  0.01595  203 GLN A OE1 
2813 N  NE2 . GLN A 180 ? 0.20935 0.32480 0.19778 0.04559  0.08967  -0.01072 203 GLN A NE2 
2822 N  N   . ARG A 181 ? 0.12480 0.19410 0.19482 -0.01309 0.04624  -0.00739 204 ARG A N   
2823 C  CA  A ARG A 181 ? 0.13849 0.19815 0.20360 -0.02119 0.04362  -0.01133 204 ARG A CA  
2824 C  CA  B ARG A 181 ? 0.13994 0.19430 0.20652 -0.01022 0.04770  -0.00941 204 ARG A CA  
2825 C  C   . ARG A 181 ? 0.13461 0.20501 0.20272 -0.01776 0.05262  -0.01982 204 ARG A C   
2826 O  O   . ARG A 181 ? 0.13275 0.21158 0.19501 -0.03833 0.04481  -0.03177 204 ARG A O   
2827 C  CB  A ARG A 181 ? 0.19434 0.23264 0.21736 -0.04046 0.04206  -0.01173 204 ARG A CB  
2828 C  CB  B ARG A 181 ? 0.18217 0.20836 0.22321 -0.00031 0.05242  -0.00568 204 ARG A CB  
2829 C  CG  A ARG A 181 ? 0.22597 0.29080 0.23774 -0.03449 0.03154  -0.00929 204 ARG A CG  
2830 C  CG  B ARG A 181 ? 0.21485 0.23550 0.24398 0.02477  0.05090  0.00126  204 ARG A CG  
2831 C  CD  A ARG A 181 ? 0.23809 0.31771 0.24845 -0.04764 0.01404  -0.00381 204 ARG A CD  
2832 C  CD  B ARG A 181 ? 0.24270 0.24909 0.25970 0.04316  0.04344  0.01459  204 ARG A CD  
2833 N  NE  A ARG A 181 ? 0.27361 0.33141 0.25306 -0.06500 0.00384  0.00482  204 ARG A NE  
2834 N  NE  B ARG A 181 ? 0.25458 0.27305 0.27102 0.05581  0.04415  0.03424  204 ARG A NE  
2835 C  CZ  A ARG A 181 ? 0.30367 0.32411 0.25439 -0.07967 -0.00006 0.01588  204 ARG A CZ  
2836 C  CZ  B ARG A 181 ? 0.26616 0.28552 0.28094 0.05268  0.03846  0.02794  204 ARG A CZ  
2837 N  NH1 A ARG A 181 ? 0.32496 0.34139 0.25548 -0.09569 0.00678  0.01495  204 ARG A NH1 
2838 N  NH1 B ARG A 181 ? 0.26681 0.22075 0.28013 0.04483  0.02835  0.02261  204 ARG A NH1 
2839 N  NH2 A ARG A 181 ? 0.29586 0.33407 0.25519 -0.07900 0.00519  0.01606  204 ARG A NH2 
2840 N  NH2 B ARG A 181 ? 0.27950 0.30835 0.29021 0.04470  0.03241  0.02933  204 ARG A NH2 
2867 N  N   . ALA A 182 ? 0.12637 0.21423 0.21252 -0.05127 0.03486  -0.00510 205 ALA A N   
2868 C  CA  . ALA A 182 ? 0.13796 0.22620 0.21605 -0.03842 0.02432  -0.01030 205 ALA A CA  
2869 C  C   . ALA A 182 ? 0.11743 0.20933 0.20233 -0.04686 0.02369  -0.02409 205 ALA A C   
2870 O  O   . ALA A 182 ? 0.14658 0.22239 0.20891 -0.04367 0.02028  -0.01335 205 ALA A O   
2871 C  CB  . ALA A 182 ? 0.13025 0.23938 0.23080 -0.05948 0.02152  0.00641  205 ALA A CB  
2877 N  N   . GLN A 183 ? 0.10747 0.23303 0.18289 -0.01528 0.02753  -0.00983 206 GLN A N   
2878 C  CA  . GLN A 183 ? 0.11075 0.19917 0.16602 -0.02135 0.02578  -0.00662 206 GLN A CA  
2879 C  C   . GLN A 183 ? 0.11953 0.21572 0.16177 -0.02414 0.01656  -0.01557 206 GLN A C   
2880 O  O   . GLN A 183 ? 0.13047 0.20980 0.16468 -0.01173 0.02561  -0.03111 206 GLN A O   
2881 C  CB  . GLN A 183 ? 0.15231 0.19018 0.17643 -0.01225 0.03252  -0.00370 206 GLN A CB  
2882 C  CG  . GLN A 183 ? 0.16485 0.17035 0.18975 -0.00448 0.03560  0.00549  206 GLN A CG  
2883 C  CD  . GLN A 183 ? 0.16622 0.21720 0.20753 0.01148  0.05045  0.01844  206 GLN A CD  
2884 O  OE1 . GLN A 183 ? 0.17346 0.29800 0.22608 0.02381  0.06507  0.02241  206 GLN A OE1 
2885 N  NE2 . GLN A 183 ? 0.16657 0.21723 0.21873 0.00087  0.04585  0.00301  206 GLN A NE2 
2894 N  N   . LEU A 184 ? 0.11134 0.19599 0.14748 -0.00974 0.02482  -0.02871 207 LEU A N   
2895 C  CA  . LEU A 184 ? 0.11126 0.19093 0.13562 -0.01477 0.01266  -0.01710 207 LEU A CA  
2896 C  C   . LEU A 184 ? 0.09830 0.19948 0.15230 -0.00437 0.00454  -0.02732 207 LEU A C   
2897 O  O   . LEU A 184 ? 0.11501 0.21268 0.16413 -0.00648 0.00225  -0.03025 207 LEU A O   
2898 C  CB  . LEU A 184 ? 0.11328 0.19166 0.12123 -0.01716 0.01475  -0.00561 207 LEU A CB  
2899 C  CG  . LEU A 184 ? 0.11588 0.16465 0.12829 -0.01309 0.01122  -0.00716 207 LEU A CG  
2900 C  CD1 . LEU A 184 ? 0.09984 0.20259 0.13851 -0.01303 0.01112  -0.01640 207 LEU A CD1 
2901 C  CD2 . LEU A 184 ? 0.11941 0.17219 0.13130 -0.02487 0.01149  -0.00080 207 LEU A CD2 
2913 N  N   . VAL A 185 ? 0.10619 0.21211 0.17494 -0.02897 0.00335  -0.05023 208 VAL A N   
2914 C  CA  . VAL A 185 ? 0.11737 0.23334 0.19982 -0.02372 -0.02811 -0.05067 208 VAL A CA  
2915 C  C   . VAL A 185 ? 0.14142 0.22348 0.21596 -0.02092 -0.01807 -0.05514 208 VAL A C   
2916 O  O   . VAL A 185 ? 0.13113 0.25118 0.21140 -0.02052 -0.02642 -0.06967 208 VAL A O   
2917 C  CB  . VAL A 185 ? 0.18600 0.21796 0.21770 -0.00533 -0.04602 -0.06192 208 VAL A CB  
2918 C  CG1 . VAL A 185 ? 0.25699 0.23662 0.23084 0.00559  -0.04654 -0.06877 208 VAL A CG1 
2919 C  CG2 . VAL A 185 ? 0.19923 0.26407 0.21717 0.02484  -0.03866 -0.05173 208 VAL A CG2 
2929 N  N   . THR A 186 ? 0.11749 0.23974 0.22677 -0.01872 -0.01068 -0.05129 209 THR A N   
2930 C  CA  . THR A 186 ? 0.12020 0.24398 0.24481 -0.05099 -0.01169 -0.03135 209 THR A CA  
2931 C  C   . THR A 186 ? 0.11418 0.22949 0.22432 -0.04169 -0.01838 -0.04164 209 THR A C   
2932 O  O   . THR A 186 ? 0.13065 0.24045 0.22847 -0.01305 -0.03803 -0.04644 209 THR A O   
2933 C  CB  . THR A 186 ? 0.09485 0.30324 0.29219 -0.04920 -0.01312 0.00137  209 THR A CB  
2934 O  OG1 . THR A 186 ? 0.14942 0.31829 0.31844 -0.05223 -0.00388 0.03010  209 THR A OG1 
2935 C  CG2 . THR A 186 ? 0.11254 0.31347 0.31223 -0.02246 -0.02213 0.00970  209 THR A CG2 
2943 N  N   . TRP A 187 ? 0.11247 0.21070 0.20118 -0.02203 -0.00784 -0.04582 210 TRP A N   
2944 C  CA  . TRP A 187 ? 0.10037 0.20017 0.17625 -0.01467 -0.01156 -0.03279 210 TRP A CA  
2945 C  C   . TRP A 187 ? 0.12688 0.21224 0.16255 -0.01022 -0.02804 -0.03465 210 TRP A C   
2946 O  O   . TRP A 187 ? 0.14768 0.23535 0.15439 -0.00018 -0.03118 -0.01455 210 TRP A O   
2947 C  CB  . TRP A 187 ? 0.11663 0.19850 0.17293 -0.01341 0.00857  -0.04183 210 TRP A CB  
2948 C  CG  . TRP A 187 ? 0.14608 0.20584 0.18363 -0.01604 0.04106  -0.01384 210 TRP A CG  
2949 C  CD1 . TRP A 187 ? 0.18939 0.20451 0.19626 -0.02151 0.04382  -0.00538 210 TRP A CD1 
2950 C  CD2 . TRP A 187 ? 0.16911 0.17133 0.17520 -0.00303 0.03962  -0.00468 210 TRP A CD2 
2951 N  NE1 . TRP A 187 ? 0.17632 0.19436 0.20017 0.00608  0.05396  0.00401  210 TRP A NE1 
2952 C  CE2 . TRP A 187 ? 0.21476 0.16198 0.18603 -0.01346 0.05654  -0.00769 210 TRP A CE2 
2953 C  CE3 . TRP A 187 ? 0.19501 0.15525 0.16832 -0.01376 0.05602  -0.01071 210 TRP A CE3 
2954 C  CZ2 . TRP A 187 ? 0.21480 0.16196 0.17695 -0.01233 0.06293  0.00333  210 TRP A CZ2 
2955 C  CZ3 . TRP A 187 ? 0.23634 0.14618 0.17114 -0.03046 0.07221  0.00013  210 TRP A CZ3 
2956 C  CH2 . TRP A 187 ? 0.24721 0.16256 0.18207 -0.03106 0.06902  -0.01204 210 TRP A CH2 
2967 N  N   . MET A 188 ? 0.12798 0.21597 0.15684 -0.00932 -0.01347 -0.04434 211 MET A N   
2968 C  CA  . MET A 188 ? 0.11092 0.20560 0.14819 -0.01656 -0.01662 -0.04586 211 MET A CA  
2969 C  C   . MET A 188 ? 0.13423 0.23905 0.16657 -0.01929 -0.02283 -0.06380 211 MET A C   
2970 O  O   . MET A 188 ? 0.15723 0.23610 0.16891 -0.03851 -0.04448 -0.04484 211 MET A O   
2971 C  CB  . MET A 188 ? 0.11564 0.19844 0.13727 -0.02665 0.00224  -0.03022 211 MET A CB  
2972 C  CG  . MET A 188 ? 0.11045 0.19017 0.11694 -0.01969 -0.00723 -0.02421 211 MET A CG  
2973 S  SD  . MET A 188 ? 0.11973 0.18808 0.10482 -0.02151 0.00272  0.00071  211 MET A SD  
2974 C  CE  . MET A 188 ? 0.10893 0.20651 0.10083 -0.01393 -0.00400 -0.01167 211 MET A CE  
2984 N  N   . LYS A 189 ? 0.12055 0.27766 0.18793 -0.02617 -0.03134 -0.07222 212 LYS A N   
2985 C  CA  . LYS A 189 ? 0.11946 0.28831 0.20673 -0.02490 -0.03657 -0.07559 212 LYS A CA  
2986 C  C   . LYS A 189 ? 0.13945 0.30288 0.19879 0.00864  -0.05809 -0.07060 212 LYS A C   
2987 O  O   . LYS A 189 ? 0.16194 0.35396 0.20344 -0.00508 -0.06325 -0.07623 212 LYS A O   
2988 C  CB  . LYS A 189 ? 0.16012 0.30048 0.22701 -0.04579 -0.05101 -0.07815 212 LYS A CB  
2989 C  CG  . LYS A 189 ? 0.23135 0.32550 0.24369 -0.06353 -0.03192 -0.05325 212 LYS A CG  
2990 C  CD  . LYS A 189 ? 0.27841 0.40156 0.26781 -0.06872 -0.03059 -0.01750 212 LYS A CD  
2991 C  CE  . LYS A 189 ? 0.35824 0.46351 0.29171 -0.06127 -0.00765 0.00363  212 LYS A CE  
2992 N  NZ  . LYS A 189 ? 0.39850 0.48046 0.30483 -0.09284 0.00226  0.01551  212 LYS A NZ  
3006 N  N   . GLY A 190 ? 0.16711 0.28977 0.20412 0.00121  -0.04860 -0.06570 213 GLY A N   
3007 C  CA  . GLY A 190 ? 0.18824 0.29694 0.19782 0.01238  -0.02972 -0.06127 213 GLY A CA  
3008 C  C   . GLY A 190 ? 0.19348 0.30384 0.18893 -0.00397 -0.02244 -0.07069 213 GLY A C   
3009 O  O   . GLY A 190 ? 0.25681 0.32797 0.20450 0.02061  -0.00784 -0.06220 213 GLY A O   
3013 N  N   . ASN A 191 ? 0.17770 0.28294 0.17895 -0.01072 -0.03715 -0.06986 214 ASN A N   
3014 C  CA  . ASN A 191 ? 0.19642 0.27741 0.17629 0.00695  -0.03533 -0.05999 214 ASN A CA  
3015 C  C   . ASN A 191 ? 0.18164 0.31018 0.17380 -0.01084 -0.03263 -0.06821 214 ASN A C   
3016 O  O   . ASN A 191 ? 0.22843 0.30056 0.18263 -0.03302 -0.00324 -0.08252 214 ASN A O   
3017 C  CB  . ASN A 191 ? 0.17640 0.28669 0.19821 -0.02107 -0.04318 -0.03432 214 ASN A CB  
3018 C  CG  . ASN A 191 ? 0.20434 0.25924 0.22390 -0.01950 -0.03331 -0.00916 214 ASN A CG  
3019 O  OD1 . ASN A 191 ? 0.26262 0.24147 0.24114 -0.02137 -0.03576 -0.01415 214 ASN A OD1 
3020 N  ND2 . ASN A 191 ? 0.21529 0.26949 0.22905 -0.03168 -0.04439 0.01540  214 ASN A ND2 
3027 N  N   . THR A 192 ? 0.21596 0.32811 0.17710 -0.01247 -0.04825 -0.06716 215 THR A N   
3028 C  CA  . THR A 192 ? 0.26373 0.32666 0.17851 -0.01619 -0.06225 -0.04697 215 THR A CA  
3029 C  C   . THR A 192 ? 0.32219 0.29439 0.17084 0.03096  -0.02717 -0.02747 215 THR A C   
3030 O  O   . THR A 192 ? 0.41262 0.33975 0.17972 0.03881  -0.04204 -0.02905 215 THR A O   
3031 C  CB  . THR A 192 ? 0.30317 0.36240 0.19077 0.01455  -0.06449 -0.04709 215 THR A CB  
3032 O  OG1 . THR A 192 ? 0.32459 0.31347 0.19116 0.04771  -0.05785 -0.04654 215 THR A OG1 
3033 C  CG2 . THR A 192 ? 0.28092 0.40950 0.20444 0.04942  -0.05789 -0.05197 215 THR A CG2 
3041 N  N   A THR A 193 ? 0.32828 0.29243 0.17493 0.03728  0.00203  0.00236  216 THR A N   
3042 N  N   B THR A 193 ? 0.33860 0.29311 0.17229 0.02963  -0.02292 -0.03006 216 THR A N   
3043 C  CA  A THR A 193 ? 0.33964 0.33688 0.18165 0.05794  -0.00888 0.01095  216 THR A CA  
3044 C  CA  B THR A 193 ? 0.35352 0.29628 0.17171 0.02677  -0.03083 -0.03981 216 THR A CA  
3045 C  C   A THR A 193 ? 0.32628 0.32552 0.16757 0.03672  -0.02504 -0.00248 216 THR A C   
3046 C  C   B THR A 193 ? 0.33002 0.28644 0.16066 0.01828  -0.04360 -0.03869 216 THR A C   
3047 O  O   A THR A 193 ? 0.33990 0.35330 0.17816 -0.01097 -0.01668 -0.00872 216 THR A O   
3048 O  O   B THR A 193 ? 0.34443 0.30976 0.16629 0.01688  -0.03670 -0.04801 216 THR A O   
3049 C  CB  A THR A 193 ? 0.31778 0.34125 0.18831 0.04160  -0.01563 0.03653  216 THR A CB  
3050 C  CB  B THR A 193 ? 0.37751 0.29842 0.17443 0.01643  -0.02736 -0.05284 216 THR A CB  
3051 O  OG1 A THR A 193 ? 0.30285 0.36950 0.18333 0.00358  0.00759  0.04303  216 THR A OG1 
3052 O  OG1 B THR A 193 ? 0.39466 0.30993 0.17844 0.01087  -0.00645 -0.06053 216 THR A OG1 
3053 C  CG2 A THR A 193 ? 0.34468 0.38579 0.20355 0.04159  -0.01666 0.03519  216 THR A CG2 
3054 C  CG2 B THR A 193 ? 0.39086 0.31015 0.17602 0.01544  -0.03809 -0.05523 216 THR A CG2 
3069 N  N   . GLY A 194 ? 0.26909 0.24931 0.14506 0.00478  -0.06859 -0.02996 217 GLY A N   
3070 C  CA  . GLY A 194 ? 0.17738 0.21700 0.12109 -0.00498 -0.03851 -0.01970 217 GLY A CA  
3071 C  C   . GLY A 194 ? 0.16163 0.21502 0.10099 0.01211  -0.02439 -0.00504 217 GLY A C   
3072 O  O   . GLY A 194 ? 0.15743 0.20862 0.09405 0.01056  -0.01512 0.01461  217 GLY A O   
3076 N  N   . ALA A 195 ? 0.15283 0.20812 0.10638 0.00741  -0.03634 -0.00489 218 ALA A N   
3077 C  CA  . ALA A 195 ? 0.14464 0.20485 0.10785 -0.01732 -0.02368 -0.00563 218 ALA A CA  
3078 C  C   . ALA A 195 ? 0.14024 0.16774 0.11828 -0.01360 -0.03593 0.01579  218 ALA A C   
3079 O  O   . ALA A 195 ? 0.15147 0.17821 0.14742 -0.01377 -0.01752 -0.00353 218 ALA A O   
3080 C  CB  . ALA A 195 ? 0.14233 0.25876 0.11180 -0.01896 -0.03325 -0.00941 218 ALA A CB  
3086 N  N   . ALA A 196 ? 0.14368 0.15625 0.11370 0.00118  -0.03872 0.00895  219 ALA A N   
3087 C  CA  . ALA A 196 ? 0.13506 0.19364 0.11192 -0.00485 -0.03727 0.02268  219 ALA A CA  
3088 C  C   . ALA A 196 ? 0.14023 0.16778 0.09549 -0.02245 -0.02897 0.01640  219 ALA A C   
3089 O  O   . ALA A 196 ? 0.16521 0.22458 0.07281 -0.01378 -0.02242 0.01800  219 ALA A O   
3090 C  CB  . ALA A 196 ? 0.17745 0.18502 0.14291 -0.01126 -0.03112 0.04671  219 ALA A CB  
3096 N  N   . SER A 197 ? 0.13402 0.16065 0.09766 -0.00470 -0.02469 0.01729  220 SER A N   
3097 C  CA  . SER A 197 ? 0.13106 0.16805 0.09031 -0.00787 -0.03695 0.01257  220 SER A CA  
3098 C  C   . SER A 197 ? 0.13024 0.17136 0.07620 -0.00093 -0.01547 0.00297  220 SER A C   
3099 O  O   . SER A 197 ? 0.14794 0.17406 0.06660 -0.00583 -0.01658 -0.01913 220 SER A O   
3100 C  CB  . SER A 197 ? 0.14246 0.14751 0.08931 -0.00939 -0.03301 0.00989  220 SER A CB  
3101 O  OG  . SER A 197 ? 0.16703 0.15933 0.10873 -0.00486 -0.01618 0.00494  220 SER A OG  
3107 N  N   . ILE A 198 ? 0.13284 0.14618 0.07399 -0.00314 -0.00878 -0.00323 221 ILE A N   
3108 C  CA  . ILE A 198 ? 0.13310 0.15755 0.07940 -0.00486 -0.03256 -0.00072 221 ILE A CA  
3109 C  C   . ILE A 198 ? 0.14207 0.15860 0.08031 0.00094  -0.02264 0.00359  221 ILE A C   
3110 O  O   . ILE A 198 ? 0.15894 0.15722 0.08403 0.00285  -0.02308 -0.01245 221 ILE A O   
3111 C  CB  . ILE A 198 ? 0.13028 0.14524 0.08565 0.00139  -0.02111 -0.00183 221 ILE A CB  
3112 C  CG1 . ILE A 198 ? 0.11925 0.13428 0.08327 -0.00810 -0.02093 0.00148  221 ILE A CG1 
3113 C  CG2 . ILE A 198 ? 0.12950 0.16645 0.08343 -0.00357 0.00122  0.01106  221 ILE A CG2 
3114 C  CD1 . ILE A 198 ? 0.13108 0.17287 0.07893 -0.01736 -0.02410 0.01222  221 ILE A CD1 
3126 N  N   . GLN A 199 ? 0.13541 0.14140 0.08562 -0.02096 -0.02171 -0.01686 222 GLN A N   
3127 C  CA  . GLN A 199 ? 0.15509 0.17266 0.09698 -0.01845 -0.00263 -0.01110 222 GLN A CA  
3128 C  C   . GLN A 199 ? 0.14541 0.16085 0.09871 -0.02084 -0.02570 -0.00666 222 GLN A C   
3129 O  O   . GLN A 199 ? 0.14882 0.17827 0.12323 -0.03482 -0.03187 -0.02437 222 GLN A O   
3130 C  CB  . GLN A 199 ? 0.13903 0.21181 0.12273 -0.05074 0.00087  -0.00512 222 GLN A CB  
3131 C  CG  . GLN A 199 ? 0.19058 0.27525 0.14537 -0.03237 0.00228  -0.00762 222 GLN A CG  
3132 C  CD  . GLN A 199 ? 0.19256 0.33314 0.16454 -0.01667 -0.01622 -0.02487 222 GLN A CD  
3133 O  OE1 . GLN A 199 ? 0.19861 0.36132 0.18192 -0.01761 -0.01837 -0.03490 222 GLN A OE1 
3134 N  NE2 . GLN A 199 ? 0.19702 0.35976 0.16423 -0.06241 -0.00064 -0.03855 222 GLN A NE2 
3143 N  N   . ALA A 200 ? 0.14671 0.16124 0.08977 -0.01048 -0.03459 -0.00597 223 ALA A N   
3144 C  CA  . ALA A 200 ? 0.14606 0.19316 0.08259 -0.01820 -0.03273 -0.02276 223 ALA A CA  
3145 C  C   . ALA A 200 ? 0.17259 0.19281 0.09277 0.00228  -0.02650 -0.00949 223 ALA A C   
3146 O  O   . ALA A 200 ? 0.22009 0.20967 0.09588 0.03567  -0.04156 -0.02138 223 ALA A O   
3147 C  CB  . ALA A 200 ? 0.14574 0.19234 0.07268 -0.01840 -0.01571 -0.00828 223 ALA A CB  
3153 N  N   . GLY A 201 ? 0.15525 0.18180 0.08652 -0.00506 -0.02125 -0.00945 224 GLY A N   
3154 C  CA  . GLY A 201 ? 0.13299 0.19346 0.08440 -0.01325 -0.01611 -0.00846 224 GLY A CA  
3155 C  C   . GLY A 201 ? 0.12556 0.17940 0.09879 0.00380  -0.01278 -0.00612 224 GLY A C   
3156 O  O   . GLY A 201 ? 0.15868 0.18995 0.12886 0.00210  0.00615  -0.00670 224 GLY A O   
3160 N  N   . LEU A 202 ? 0.14356 0.17228 0.09543 0.00298  -0.02876 0.00732  225 LEU A N   
3161 C  CA  . LEU A 202 ? 0.16285 0.15341 0.10253 -0.02682 -0.03268 -0.00242 225 LEU A CA  
3162 C  C   . LEU A 202 ? 0.17689 0.17403 0.10737 -0.02751 -0.02807 0.00009  225 LEU A C   
3163 O  O   . LEU A 202 ? 0.17041 0.17424 0.11757 -0.02360 -0.03684 0.01396  225 LEU A O   
3164 C  CB  . LEU A 202 ? 0.17105 0.16935 0.11058 -0.03705 -0.02385 0.01068  225 LEU A CB  
3165 C  CG  . LEU A 202 ? 0.19524 0.17823 0.10127 -0.02437 -0.05112 0.01507  225 LEU A CG  
3166 C  CD1 . LEU A 202 ? 0.25825 0.18624 0.10287 -0.05842 -0.05348 0.02240  225 LEU A CD1 
3167 C  CD2 . LEU A 202 ? 0.18513 0.22490 0.12221 -0.03175 -0.05185 0.02065  225 LEU A CD2 
3179 N  N   . PRO A 203 ? 0.17561 0.15753 0.11962 -0.03335 -0.03289 0.00588  226 PRO A N   
3180 C  CA  . PRO A 203 ? 0.16373 0.15220 0.12146 -0.02933 -0.03184 0.00127  226 PRO A CA  
3181 C  C   . PRO A 203 ? 0.15944 0.16530 0.12432 -0.03375 -0.03719 -0.00316 226 PRO A C   
3182 O  O   . PRO A 203 ? 0.18178 0.18825 0.13733 -0.05331 -0.04112 -0.01703 226 PRO A O   
3183 C  CB  . PRO A 203 ? 0.17865 0.17631 0.13468 -0.04196 -0.04244 -0.00596 226 PRO A CB  
3184 C  CG  . PRO A 203 ? 0.17655 0.19091 0.13772 -0.01570 -0.04313 0.00078  226 PRO A CG  
3185 C  CD  . PRO A 203 ? 0.16265 0.18637 0.12408 -0.01830 -0.03254 -0.00754 226 PRO A CD  
3193 N  N   . ALA A 204 ? 0.16288 0.18687 0.13425 -0.02508 -0.04249 -0.00234 227 ALA A N   
3194 C  CA  . ALA A 204 ? 0.16326 0.24966 0.15882 -0.00723 -0.02838 -0.00098 227 ALA A CA  
3195 C  C   . ALA A 204 ? 0.15350 0.30111 0.16633 -0.00553 -0.02268 -0.01349 227 ALA A C   
3196 O  O   . ALA A 204 ? 0.20901 0.35429 0.18000 0.01459  0.01817  -0.02232 227 ALA A O   
3197 C  CB  . ALA A 204 ? 0.20317 0.26642 0.17007 0.00933  -0.03190 0.00417  227 ALA A CB  
3203 N  N   . SER A 205 ? 0.17512 0.27474 0.16249 -0.04768 -0.02473 -0.00522 228 SER A N   
3204 C  CA  . SER A 205 ? 0.21291 0.30845 0.16054 -0.06937 -0.02248 -0.01012 228 SER A CA  
3205 C  C   . SER A 205 ? 0.22080 0.32950 0.14630 -0.08491 0.00216  -0.01218 228 SER A C   
3206 O  O   . SER A 205 ? 0.26817 0.40416 0.14657 -0.13108 0.00401  -0.00317 228 SER A O   
3207 C  CB  . SER A 205 ? 0.25338 0.31513 0.17555 -0.11569 -0.04506 0.00364  228 SER A CB  
3208 O  OG  . SER A 205 ? 0.29933 0.28801 0.19046 -0.12668 -0.05929 0.00745  228 SER A OG  
3214 N  N   . TRP A 206 ? 0.20239 0.26407 0.13758 -0.05199 -0.01044 -0.01943 229 TRP A N   
3215 C  CA  . TRP A 206 ? 0.23876 0.21757 0.13402 -0.05112 -0.02240 -0.01315 229 TRP A CA  
3216 C  C   . TRP A 206 ? 0.24002 0.21723 0.14981 -0.04216 -0.00234 -0.01430 229 TRP A C   
3217 O  O   . TRP A 206 ? 0.32629 0.23710 0.17160 0.03588  0.00639  0.01573  229 TRP A O   
3218 C  CB  . TRP A 206 ? 0.24900 0.18097 0.13482 -0.05105 -0.02268 -0.00498 229 TRP A CB  
3219 C  CG  . TRP A 206 ? 0.24481 0.17931 0.13850 -0.04180 -0.04626 -0.01005 229 TRP A CG  
3220 C  CD1 . TRP A 206 ? 0.26169 0.19951 0.15385 -0.03837 -0.03830 -0.00513 229 TRP A CD1 
3221 C  CD2 . TRP A 206 ? 0.22947 0.15403 0.13585 -0.04869 -0.02614 0.00920  229 TRP A CD2 
3222 N  NE1 . TRP A 206 ? 0.26212 0.18304 0.16165 -0.06268 -0.02639 -0.01134 229 TRP A NE1 
3223 C  CE2 . TRP A 206 ? 0.24561 0.17508 0.14856 -0.01769 -0.03371 0.00414  229 TRP A CE2 
3224 C  CE3 . TRP A 206 ? 0.23259 0.17650 0.13751 -0.05994 -0.02032 0.02013  229 TRP A CE3 
3225 C  CZ2 . TRP A 206 ? 0.30944 0.20404 0.16131 -0.03360 -0.01858 -0.00254 229 TRP A CZ2 
3226 C  CZ3 . TRP A 206 ? 0.25553 0.20154 0.15997 -0.02680 -0.00242 0.01424  229 TRP A CZ3 
3227 C  CH2 . TRP A 206 ? 0.30068 0.22227 0.17130 -0.00931 0.00108  0.01294  229 TRP A CH2 
3238 N  N   . VAL A 207 ? 0.21445 0.20985 0.15711 -0.05763 -0.01729 -0.04155 230 VAL A N   
3239 C  CA  . VAL A 207 ? 0.19809 0.23511 0.18217 -0.06421 0.00030  -0.04407 230 VAL A CA  
3240 C  C   . VAL A 207 ? 0.19011 0.20248 0.16316 -0.03190 -0.01871 -0.03556 230 VAL A C   
3241 O  O   . VAL A 207 ? 0.21048 0.19712 0.15616 -0.05516 -0.03655 -0.01036 230 VAL A O   
3242 C  CB  . VAL A 207 ? 0.21398 0.30521 0.21374 -0.09333 0.00935  -0.07303 230 VAL A CB  
3243 C  CG1 . VAL A 207 ? 0.22930 0.33903 0.22769 -0.10135 0.02944  -0.08663 230 VAL A CG1 
3244 C  CG2 . VAL A 207 ? 0.24303 0.33897 0.22732 -0.11161 0.01238  -0.07713 230 VAL A CG2 
3254 N  N   . VAL A 208 ? 0.16519 0.19596 0.15580 -0.01841 -0.03766 -0.02752 231 VAL A N   
3255 C  CA  . VAL A 208 ? 0.16584 0.17874 0.15454 -0.01837 -0.02136 -0.01620 231 VAL A CA  
3256 C  C   . VAL A 208 ? 0.15243 0.17164 0.14799 -0.00977 -0.01032 -0.02654 231 VAL A C   
3257 O  O   . VAL A 208 ? 0.16170 0.22902 0.17540 -0.01033 -0.02339 -0.04668 231 VAL A O   
3258 C  CB  . VAL A 208 ? 0.17322 0.21112 0.15474 -0.01960 -0.01490 -0.02805 231 VAL A CB  
3259 C  CG1 . VAL A 208 ? 0.18830 0.22582 0.15515 -0.05096 -0.01479 -0.02293 231 VAL A CG1 
3260 C  CG2 . VAL A 208 ? 0.20491 0.24899 0.15951 -0.01306 -0.02866 -0.04584 231 VAL A CG2 
3270 N  N   . GLY A 209 ? 0.13484 0.16497 0.12661 -0.03965 0.00807  -0.00698 232 GLY A N   
3271 C  CA  . GLY A 209 ? 0.12767 0.16313 0.12423 -0.03415 0.01831  -0.00410 232 GLY A CA  
3272 C  C   . GLY A 209 ? 0.12083 0.15022 0.13024 -0.02253 -0.00266 -0.00698 232 GLY A C   
3273 O  O   . GLY A 209 ? 0.12645 0.17106 0.17287 -0.01614 -0.00841 0.02536  232 GLY A O   
3277 N  N   . ASP A 210 ? 0.10901 0.13761 0.11922 -0.02073 0.00291  -0.00302 233 ASP A N   
3278 C  CA  . ASP A 210 ? 0.11509 0.13386 0.10480 -0.01216 0.01075  -0.00638 233 ASP A CA  
3279 C  C   . ASP A 210 ? 0.10359 0.14308 0.09295 -0.00441 0.00550  -0.00260 233 ASP A C   
3280 O  O   . ASP A 210 ? 0.11345 0.14758 0.10418 -0.00940 0.00697  -0.00366 233 ASP A O   
3281 C  CB  . ASP A 210 ? 0.11042 0.14935 0.10222 -0.00658 0.01219  -0.00531 233 ASP A CB  
3282 C  CG  . ASP A 210 ? 0.09646 0.17159 0.09864 -0.01175 0.01445  -0.01181 233 ASP A CG  
3283 O  OD1 . ASP A 210 ? 0.11968 0.19201 0.12659 -0.02363 0.00940  0.01555  233 ASP A OD1 
3284 O  OD2 . ASP A 210 ? 0.11805 0.16698 0.09146 -0.02632 -0.00222 0.00961  233 ASP A OD2 
3289 N  N   . LYS A 211 ? 0.09842 0.14338 0.09034 -0.01174 0.00106  -0.01006 234 LYS A N   
3290 C  CA  . LYS A 211 ? 0.10843 0.13597 0.09294 -0.01289 0.00470  -0.00779 234 LYS A CA  
3291 C  C   . LYS A 211 ? 0.11427 0.13317 0.09168 -0.01250 0.00177  -0.00826 234 LYS A C   
3292 O  O   . LYS A 211 ? 0.10281 0.14329 0.09538 -0.00632 0.00139  0.00011  234 LYS A O   
3293 C  CB  . LYS A 211 ? 0.13326 0.13972 0.09830 -0.02191 0.02545  -0.01876 234 LYS A CB  
3294 C  CG  . LYS A 211 ? 0.13088 0.15832 0.11086 -0.02733 0.03068  -0.02016 234 LYS A CG  
3295 C  CD  . LYS A 211 ? 0.14030 0.15006 0.12600 -0.01874 0.03609  -0.01960 234 LYS A CD  
3296 C  CE  . LYS A 211 ? 0.14230 0.16977 0.12077 -0.00642 0.03840  -0.00880 234 LYS A CE  
3297 N  NZ  . LYS A 211 ? 0.14599 0.16336 0.13172 -0.01223 0.03176  -0.00628 234 LYS A NZ  
3311 N  N   . THR A 212 ? 0.11453 0.13771 0.08955 -0.00415 0.00475  0.00088  235 THR A N   
3312 C  CA  . THR A 212 ? 0.12371 0.14212 0.09246 -0.01194 0.00608  0.00214  235 THR A CA  
3313 C  C   . THR A 212 ? 0.10869 0.15190 0.08878 -0.01270 0.00330  -0.00406 235 THR A C   
3314 O  O   . THR A 212 ? 0.12974 0.14925 0.09308 -0.00014 0.02295  -0.01400 235 THR A O   
3315 C  CB  . THR A 212 ? 0.16369 0.16759 0.11158 -0.02000 -0.01776 0.01310  235 THR A CB  
3316 O  OG1 . THR A 212 ? 0.21497 0.18578 0.16255 -0.00146 -0.05224 0.00502  235 THR A OG1 
3317 C  CG2 . THR A 212 ? 0.18728 0.20551 0.09971 -0.04241 -0.00451 0.01178  235 THR A CG2 
3325 N  N   . GLY A 213 ? 0.12431 0.14601 0.09170 -0.00295 0.01848  -0.00984 236 GLY A N   
3326 C  CA  . GLY A 213 ? 0.14002 0.15811 0.09508 -0.02510 0.02345  -0.00056 236 GLY A CA  
3327 C  C   . GLY A 213 ? 0.13305 0.15745 0.10067 -0.01354 0.02425  -0.01027 236 GLY A C   
3328 O  O   . GLY A 213 ? 0.16753 0.16159 0.09862 -0.00099 0.04001  -0.01930 236 GLY A O   
3332 N  N   A SER A 214 ? 0.13073 0.15599 0.10571 -0.00571 0.02396  0.00022  237 SER A N   
3333 N  N   B SER A 214 ? 0.13616 0.16325 0.10251 -0.02625 0.01992  -0.00217 237 SER A N   
3334 N  N   C SER A 214 ? 0.13464 0.14976 0.11127 -0.01977 0.03103  0.00226  237 SER A N   
3335 C  CA  A SER A 214 ? 0.14771 0.16898 0.11017 -0.01035 0.00882  0.01957  237 SER A CA  
3336 C  CA  B SER A 214 ? 0.14894 0.18225 0.10674 -0.04467 0.00669  0.00794  237 SER A CA  
3337 C  CA  C SER A 214 ? 0.15565 0.18338 0.12607 -0.04520 0.01043  0.01878  237 SER A CA  
3338 C  C   A SER A 214 ? 0.14764 0.14140 0.10149 -0.00433 0.02455  0.02029  237 SER A C   
3339 C  C   B SER A 214 ? 0.14682 0.16199 0.10209 -0.02298 0.01706  0.01273  237 SER A C   
3340 C  C   C SER A 214 ? 0.14315 0.14510 0.10699 -0.00915 0.01998  0.01983  237 SER A C   
3341 O  O   A SER A 214 ? 0.16637 0.13902 0.10722 -0.00406 0.04255  0.00794  237 SER A O   
3342 O  O   B SER A 214 ? 0.15850 0.16836 0.10551 -0.01733 0.02527  0.00720  237 SER A O   
3343 O  O   C SER A 214 ? 0.15784 0.15924 0.11275 -0.00963 0.03076  -0.00284 237 SER A O   
3344 C  CB  A SER A 214 ? 0.21246 0.17853 0.11535 -0.00518 -0.02273 0.02693  237 SER A CB  
3345 C  CB  B SER A 214 ? 0.19288 0.21908 0.11217 -0.07569 -0.02004 0.00738  237 SER A CB  
3346 C  CB  C SER A 214 ? 0.26283 0.22779 0.15080 -0.07750 -0.02386 0.02368  237 SER A CB  
3347 O  OG  A SER A 214 ? 0.23571 0.18936 0.11821 0.00841  -0.03770 0.03847  237 SER A OG  
3348 O  OG  B SER A 214 ? 0.19877 0.24747 0.11627 -0.07428 -0.02786 0.01377  237 SER A OG  
3349 O  OG  C SER A 214 ? 0.30956 0.27130 0.17123 -0.06347 -0.03488 0.03542  237 SER A OG  
3365 N  N   . GLY A 215 ? 0.14034 0.15800 0.10203 -0.02107 0.01926  0.01371  238 GLY A N   
3366 C  CA  . GLY A 215 ? 0.16493 0.16274 0.10633 -0.02214 0.05186  -0.00222 238 GLY A CA  
3367 C  C   . GLY A 215 ? 0.17669 0.15200 0.10002 -0.03778 0.03432  -0.00987 238 GLY A C   
3368 O  O   . GLY A 215 ? 0.17787 0.17486 0.09429 -0.03769 0.02333  -0.00208 238 GLY A O   
3372 N  N   . GLY A 216 ? 0.16901 0.14832 0.10109 -0.02534 0.02072  -0.01176 239 GLY A N   
3373 C  CA  . GLY A 216 ? 0.16370 0.15989 0.11860 -0.04969 0.02889  0.00614  239 GLY A CA  
3374 C  C   . GLY A 216 ? 0.14580 0.18478 0.09402 -0.02364 0.02452  -0.00307 239 GLY A C   
3375 O  O   . GLY A 216 ? 0.16023 0.17838 0.09264 -0.03337 0.01736  -0.00561 239 GLY A O   
3379 N  N   . TYR A 217 ? 0.16582 0.17571 0.10968 -0.04783 0.04257  0.01105  240 TYR A N   
3380 C  CA  . TYR A 217 ? 0.15133 0.21143 0.10669 -0.02918 0.02868  0.00892  240 TYR A CA  
3381 C  C   . TYR A 217 ? 0.15209 0.19892 0.09564 -0.04744 0.02809  0.00755  240 TYR A C   
3382 O  O   . TYR A 217 ? 0.15740 0.19218 0.09525 -0.03091 0.01988  0.00769  240 TYR A O   
3383 C  CB  . TYR A 217 ? 0.16517 0.20764 0.11352 -0.05254 0.03401  -0.00661 240 TYR A CB  
3384 C  CG  . TYR A 217 ? 0.17413 0.20659 0.12541 -0.05622 0.02791  0.00295  240 TYR A CG  
3385 C  CD1 . TYR A 217 ? 0.20396 0.21497 0.12705 -0.06930 -0.00217 0.00227  240 TYR A CD1 
3386 C  CD2 . TYR A 217 ? 0.16613 0.22480 0.13160 -0.05905 0.03678  0.01581  240 TYR A CD2 
3387 C  CE1 . TYR A 217 ? 0.23150 0.22056 0.14130 -0.05693 -0.00554 0.01730  240 TYR A CE1 
3388 C  CE2 . TYR A 217 ? 0.18860 0.27841 0.14825 -0.07186 0.02455  0.02173  240 TYR A CE2 
3389 C  CZ  . TYR A 217 ? 0.22375 0.24974 0.16074 -0.11439 0.00362  0.00973  240 TYR A CZ  
3390 O  OH  . TYR A 217 ? 0.27411 0.30937 0.17764 -0.13008 0.00598  0.01735  240 TYR A OH  
3400 N  N   . GLY A 218 ? 0.14021 0.18787 0.09406 -0.03815 0.02808  -0.00102 241 GLY A N   
3401 C  CA  . GLY A 218 ? 0.15136 0.18065 0.09681 -0.03053 0.01851  0.00084  241 GLY A CA  
3402 C  C   . GLY A 218 ? 0.15153 0.16752 0.09112 -0.02310 0.01957  0.01059  241 GLY A C   
3403 O  O   . GLY A 218 ? 0.15772 0.17405 0.08275 -0.01798 0.01528  0.00427  241 GLY A O   
3407 N  N   . THR A 219 ? 0.15008 0.15697 0.09109 -0.02059 0.01713  -0.00725 242 THR A N   
3408 C  CA  . THR A 219 ? 0.12112 0.16254 0.08597 -0.02239 0.02091  -0.00122 242 THR A CA  
3409 C  C   . THR A 219 ? 0.13046 0.17047 0.09283 -0.00736 0.02734  -0.00417 242 THR A C   
3410 O  O   . THR A 219 ? 0.14756 0.16164 0.10068 -0.01783 0.03354  0.00289  242 THR A O   
3411 C  CB  . THR A 219 ? 0.14470 0.15619 0.09003 -0.02134 0.02777  -0.00234 242 THR A CB  
3412 O  OG1 . THR A 219 ? 0.14695 0.17106 0.10317 -0.02807 0.01905  -0.01238 242 THR A OG1 
3413 C  CG2 . THR A 219 ? 0.14064 0.16617 0.09761 -0.01344 0.01539  -0.01648 242 THR A CG2 
3421 N  N   . THR A 220 ? 0.11946 0.15490 0.08738 -0.00134 0.02404  0.01228  243 THR A N   
3422 C  CA  . THR A 220 ? 0.11571 0.15582 0.08214 -0.01273 0.00331  0.01253  243 THR A CA  
3423 C  C   . THR A 220 ? 0.10408 0.14879 0.07850 0.00320  0.00725  0.00128  243 THR A C   
3424 O  O   . THR A 220 ? 0.11533 0.15777 0.07266 -0.00806 0.01237  0.00143  243 THR A O   
3425 C  CB  . THR A 220 ? 0.16224 0.17493 0.08624 -0.01783 0.00179  0.01282  243 THR A CB  
3426 O  OG1 . THR A 220 ? 0.16053 0.19372 0.07830 -0.03435 -0.00339 0.02216  243 THR A OG1 
3427 C  CG2 . THR A 220 ? 0.14910 0.22004 0.08510 -0.02350 -0.01298 0.02903  243 THR A CG2 
3435 N  N   . ASN A 221 ? 0.11521 0.14464 0.06591 -0.00433 0.01248  0.00056  244 ASN A N   
3436 C  CA  . ASN A 221 ? 0.12497 0.15386 0.06309 -0.01573 -0.00632 -0.00433 244 ASN A CA  
3437 C  C   . ASN A 221 ? 0.11316 0.14088 0.06654 -0.00771 0.00298  -0.00320 244 ASN A C   
3438 O  O   . ASN A 221 ? 0.10447 0.14065 0.07394 -0.00284 -0.00420 0.00565  244 ASN A O   
3439 C  CB  . ASN A 221 ? 0.11205 0.14484 0.08002 -0.02172 0.00400  0.00165  244 ASN A CB  
3440 C  CG  . ASN A 221 ? 0.11581 0.15637 0.07779 -0.00985 0.00905  0.00670  244 ASN A CG  
3441 O  OD1 . ASN A 221 ? 0.11765 0.16899 0.08485 -0.01796 0.00448  -0.00113 244 ASN A OD1 
3442 N  ND2 . ASN A 221 ? 0.12438 0.16693 0.08327 -0.02862 0.01134  -0.01092 244 ASN A ND2 
3449 N  N   . ASP A 222 ? 0.10453 0.12735 0.08108 -0.00660 0.00209  0.00366  245 ASP A N   
3450 C  CA  . ASP A 222 ? 0.09112 0.13396 0.08567 -0.00310 -0.00664 0.00900  245 ASP A CA  
3451 C  C   . ASP A 222 ? 0.11595 0.12854 0.06735 -0.00752 0.00640  -0.00457 245 ASP A C   
3452 O  O   . ASP A 222 ? 0.12369 0.13636 0.07061 0.00164  -0.00419 -0.00732 245 ASP A O   
3453 C  CB  . ASP A 222 ? 0.10600 0.14532 0.07065 -0.01668 -0.01140 -0.00872 245 ASP A CB  
3454 C  CG  . ASP A 222 ? 0.09781 0.14509 0.07219 -0.00992 -0.00575 0.00680  245 ASP A CG  
3455 O  OD1 . ASP A 222 ? 0.11812 0.16843 0.07639 -0.00745 -0.00310 -0.00570 245 ASP A OD1 
3456 O  OD2 . ASP A 222 ? 0.10603 0.16148 0.08046 -0.01559 -0.00638 -0.00221 245 ASP A OD2 
3461 N  N   . ILE A 223 ? 0.09764 0.14595 0.06060 0.00352  0.00606  -0.00010 246 ILE A N   
3462 C  CA  . ILE A 223 ? 0.09518 0.13697 0.06510 -0.00194 -0.00019 0.00786  246 ILE A CA  
3463 C  C   . ILE A 223 ? 0.11001 0.14048 0.06963 0.01461  0.00232  0.00185  246 ILE A C   
3464 O  O   . ILE A 223 ? 0.10996 0.14641 0.08759 -0.00613 0.00785  -0.00174 246 ILE A O   
3465 C  CB  . ILE A 223 ? 0.10026 0.15555 0.07216 0.00027  -0.00035 0.00466  246 ILE A CB  
3466 C  CG1 . ILE A 223 ? 0.11794 0.16032 0.08162 -0.01345 -0.00169 0.00583  246 ILE A CG1 
3467 C  CG2 . ILE A 223 ? 0.10737 0.15270 0.08202 0.00088  -0.00111 0.00506  246 ILE A CG2 
3468 C  CD1 . ILE A 223 ? 0.11418 0.18334 0.08564 -0.00437 0.01350  -0.00822 246 ILE A CD1 
3480 N  N   . ALA A 224 ? 0.10857 0.12813 0.09146 -0.00414 -0.01346 0.00113  247 ALA A N   
3481 C  CA  . ALA A 224 ? 0.12160 0.13504 0.09161 -0.00451 -0.01156 -0.00259 247 ALA A CA  
3482 C  C   . ALA A 224 ? 0.11847 0.14889 0.09128 -0.00512 -0.01280 -0.00737 247 ALA A C   
3483 O  O   . ALA A 224 ? 0.14333 0.13756 0.09011 -0.01735 0.00350  0.00098  247 ALA A O   
3484 C  CB  . ALA A 224 ? 0.15116 0.13775 0.10855 -0.04046 -0.01685 0.00706  247 ALA A CB  
3490 N  N   . VAL A 225 ? 0.13492 0.13852 0.09876 -0.01564 0.00198  -0.00481 248 VAL A N   
3491 C  CA  . VAL A 225 ? 0.14416 0.14747 0.09857 -0.03163 0.00800  0.00640  248 VAL A CA  
3492 C  C   . VAL A 225 ? 0.13422 0.13324 0.10926 -0.03268 -0.01065 0.00509  248 VAL A C   
3493 O  O   . VAL A 225 ? 0.16181 0.15382 0.12065 -0.01745 -0.01392 0.00711  248 VAL A O   
3494 C  CB  . VAL A 225 ? 0.16463 0.19227 0.10952 -0.02245 0.02137  0.02008  248 VAL A CB  
3495 C  CG1 . VAL A 225 ? 0.18096 0.25998 0.12581 -0.02681 0.01179  0.02556  248 VAL A CG1 
3496 C  CG2 . VAL A 225 ? 0.19084 0.17945 0.11534 -0.05958 0.01583  0.01833  248 VAL A CG2 
3506 N  N   . ILE A 226 ? 0.15792 0.13422 0.12792 -0.03082 -0.01795 0.00258  249 ILE A N   
3507 C  CA  . ILE A 226 ? 0.16000 0.13861 0.12415 -0.03521 -0.01547 0.00313  249 ILE A CA  
3508 C  C   . ILE A 226 ? 0.16999 0.15825 0.13540 -0.04735 -0.01299 0.00455  249 ILE A C   
3509 O  O   . ILE A 226 ? 0.19899 0.16148 0.12650 -0.05216 -0.01458 0.01218  249 ILE A O   
3510 C  CB  . ILE A 226 ? 0.19152 0.16576 0.11546 -0.06560 -0.01754 -0.00100 249 ILE A CB  
3511 C  CG1 . ILE A 226 ? 0.18058 0.18554 0.12534 -0.06080 -0.01088 0.01232  249 ILE A CG1 
3512 C  CG2 . ILE A 226 ? 0.23980 0.16119 0.10414 -0.03547 -0.03266 -0.00108 249 ILE A CG2 
3513 C  CD1 . ILE A 226 ? 0.19402 0.16469 0.14245 -0.04609 -0.02306 0.03505  249 ILE A CD1 
3525 N  N   . TRP A 227 ? 0.18230 0.18150 0.15190 -0.07199 -0.00486 0.01130  250 TRP A N   
3526 C  CA  . TRP A 227 ? 0.21807 0.23234 0.16164 -0.09552 -0.02928 0.01162  250 TRP A CA  
3527 C  C   . TRP A 227 ? 0.24326 0.21315 0.15662 -0.07954 -0.04600 0.02143  250 TRP A C   
3528 O  O   . TRP A 227 ? 0.24778 0.22679 0.16404 -0.09890 -0.07010 0.01104  250 TRP A O   
3529 C  CB  . TRP A 227 ? 0.23463 0.32052 0.17495 -0.15019 -0.02096 0.00490  250 TRP A CB  
3530 C  CG  . TRP A 227 ? 0.25813 0.42265 0.19155 -0.16323 0.01657  -0.01664 250 TRP A CG  
3531 C  CD1 . TRP A 227 ? 0.29861 0.48819 0.19596 -0.15969 0.02902  -0.00616 250 TRP A CD1 
3532 C  CD2 . TRP A 227 ? 0.26126 0.46219 0.20379 -0.15616 0.03585  -0.03474 250 TRP A CD2 
3533 N  NE1 . TRP A 227 ? 0.32483 0.52651 0.20848 -0.14355 0.03844  -0.00867 250 TRP A NE1 
3534 C  CE2 . TRP A 227 ? 0.28440 0.50863 0.21556 -0.15084 0.04261  -0.02895 250 TRP A CE2 
3535 C  CE3 . TRP A 227 ? 0.25280 0.45893 0.21523 -0.16290 0.03154  -0.06671 250 TRP A CE3 
3536 C  CZ2 . TRP A 227 ? 0.24988 0.51210 0.22224 -0.15001 0.06783  -0.03341 250 TRP A CZ2 
3537 C  CZ3 . TRP A 227 ? 0.25904 0.48354 0.22287 -0.14431 0.03762  -0.06937 250 TRP A CZ3 
3538 C  CH2 . TRP A 227 ? 0.25774 0.50674 0.22317 -0.12469 0.06727  -0.05691 250 TRP A CH2 
3549 N  N   . PRO A 228 ? 0.27352 0.18699 0.15176 -0.08114 -0.04591 0.01658  251 PRO A N   
3550 C  CA  . PRO A 228 ? 0.32471 0.20822 0.15846 -0.05837 -0.05020 0.01714  251 PRO A CA  
3551 C  C   . PRO A 228 ? 0.34322 0.23760 0.17710 -0.09458 -0.09261 0.00980  251 PRO A C   
3552 O  O   . PRO A 228 ? 0.36631 0.22941 0.18003 -0.12249 -0.07741 0.01978  251 PRO A O   
3553 C  CB  . PRO A 228 ? 0.33101 0.20162 0.15815 -0.04995 -0.04529 0.01612  251 PRO A CB  
3554 C  CG  . PRO A 228 ? 0.30623 0.20371 0.15685 -0.06817 -0.03817 0.01197  251 PRO A CG  
3555 C  CD  . PRO A 228 ? 0.27459 0.19195 0.14345 -0.06781 -0.03534 0.02830  251 PRO A CD  
3563 N  N   . LYS A 229 ? 0.37312 0.25520 0.19781 -0.11413 -0.11591 0.00726  252 LYS A N   
3564 C  CA  . LYS A 229 ? 0.41444 0.29670 0.23134 -0.15248 -0.12180 0.01446  252 LYS A CA  
3565 C  C   . LYS A 229 ? 0.43076 0.29987 0.23789 -0.15521 -0.11828 0.00325  252 LYS A C   
3566 O  O   . LYS A 229 ? 0.45373 0.27104 0.23540 -0.12809 -0.11483 0.00038  252 LYS A O   
3567 C  CB  . LYS A 229 ? 0.49213 0.37773 0.26248 -0.18463 -0.13733 0.01346  252 LYS A CB  
3568 C  CG  . LYS A 229 ? 0.53250 0.48237 0.29292 -0.21531 -0.14952 0.01600  252 LYS A CG  
3569 C  CD  . LYS A 229 ? 0.61517 0.59694 0.30708 -0.22416 -0.16036 0.00375  252 LYS A CD  
3570 C  CE  . LYS A 229 ? 0.68996 0.68781 0.32281 -0.22163 -0.15073 0.00433  252 LYS A CE  
3571 N  NZ  . LYS A 229 ? 0.73637 0.75945 0.34000 -0.19844 -0.13738 0.01084  252 LYS A NZ  
3585 N  N   . ASP A 230 ? 0.44987 0.29976 0.25623 -0.18603 -0.10018 0.01184  253 ASP A N   
3586 C  CA  . ASP A 230 ? 0.46833 0.31454 0.27431 -0.20137 -0.09958 0.01742  253 ASP A CA  
3587 C  C   . ASP A 230 ? 0.46627 0.26442 0.26629 -0.17121 -0.08952 0.01786  253 ASP A C   
3588 O  O   . ASP A 230 ? 0.49274 0.27998 0.28473 -0.15855 -0.10326 -0.00806 253 ASP A O   
3589 C  CB  . ASP A 230 ? 0.47692 0.34770 0.30017 -0.21318 -0.10280 0.00758  253 ASP A CB  
3590 C  CG  . ASP A 230 ? 0.50538 0.46014 0.31581 -0.19661 -0.10120 0.01042  253 ASP A CG  
3591 O  OD1 . ASP A 230 ? 0.51184 0.51790 0.32817 -0.15042 -0.08398 0.01249  253 ASP A OD1 
3592 O  OD2 . ASP A 230 ? 0.53510 0.50889 0.32675 -0.19221 -0.08649 0.01652  253 ASP A OD2 
3597 N  N   A ARG A 231 ? 0.43861 0.23704 0.24987 -0.16673 -0.08137 0.02283  254 ARG A N   
3598 N  N   B ARG A 231 ? 0.43617 0.24929 0.25163 -0.17734 -0.07043 0.02573  254 ARG A N   
3599 C  CA  A ARG A 231 ? 0.44544 0.22356 0.23721 -0.15211 -0.08087 0.01920  254 ARG A CA  
3600 C  CA  B ARG A 231 ? 0.43470 0.24537 0.24076 -0.17715 -0.05896 0.02606  254 ARG A CA  
3601 C  C   A ARG A 231 ? 0.38114 0.18050 0.21340 -0.12609 -0.08889 0.03695  254 ARG A C   
3602 C  C   B ARG A 231 ? 0.38307 0.19777 0.21665 -0.14151 -0.07261 0.03981  254 ARG A C   
3603 O  O   A ARG A 231 ? 0.36311 0.22855 0.20758 -0.11952 -0.08771 0.04924  254 ARG A O   
3604 O  O   B ARG A 231 ? 0.37002 0.23248 0.21114 -0.13911 -0.06821 0.05470  254 ARG A O   
3605 C  CB  A ARG A 231 ? 0.50110 0.27410 0.25142 -0.12359 -0.07895 0.00902  254 ARG A CB  
3606 C  CB  B ARG A 231 ? 0.48290 0.29585 0.25743 -0.20535 -0.04616 0.01984  254 ARG A CB  
3607 C  CG  A ARG A 231 ? 0.56800 0.32015 0.26722 -0.06547 -0.07685 -0.00059 254 ARG A CG  
3608 C  CG  B ARG A 231 ? 0.54439 0.35368 0.27535 -0.18918 -0.03431 0.01151  254 ARG A CG  
3609 C  CD  A ARG A 231 ? 0.63157 0.38460 0.27978 -0.00942 -0.07404 -0.01882 254 ARG A CD  
3610 C  CD  B ARG A 231 ? 0.59831 0.42829 0.29249 -0.17831 -0.02596 -0.00853 254 ARG A CD  
3611 N  NE  A ARG A 231 ? 0.67997 0.41614 0.28514 0.03481  -0.07296 -0.04189 254 ARG A NE  
3612 N  NE  B ARG A 231 ? 0.63353 0.47360 0.30364 -0.18367 -0.01820 -0.02591 254 ARG A NE  
3613 C  CZ  A ARG A 231 ? 0.71125 0.44297 0.28838 0.07309  -0.07033 -0.05527 254 ARG A CZ  
3614 C  CZ  B ARG A 231 ? 0.66774 0.51578 0.31395 -0.17005 -0.01061 -0.03487 254 ARG A CZ  
3615 N  NH1 A ARG A 231 ? 0.72058 0.44941 0.28802 0.09418  -0.06474 -0.05794 254 ARG A NH1 
3616 N  NH1 B ARG A 231 ? 0.67930 0.53265 0.31839 -0.16508 -0.01533 -0.03102 254 ARG A NH1 
3617 N  NH2 A ARG A 231 ? 0.73118 0.46696 0.28937 0.07269  -0.07470 -0.05910 254 ARG A NH2 
3618 N  NH2 B ARG A 231 ? 0.68135 0.52675 0.31711 -0.15983 -0.00374 -0.04090 254 ARG A NH2 
3645 N  N   . ALA A 232 ? 0.36351 0.18068 0.21032 -0.10499 -0.07452 0.03717  255 ALA A N   
3646 C  CA  . ALA A 232 ? 0.29436 0.18110 0.17796 -0.08296 -0.05945 0.04293  255 ALA A CA  
3647 C  C   . ALA A 232 ? 0.24275 0.16632 0.15065 -0.06755 -0.03986 0.03680  255 ALA A C   
3648 O  O   . ALA A 232 ? 0.27645 0.16758 0.15603 -0.06269 -0.04726 0.02360  255 ALA A O   
3649 C  CB  . ALA A 232 ? 0.30138 0.18898 0.18605 -0.03106 -0.05720 0.03511  255 ALA A CB  
3655 N  N   A PRO A 233 ? 0.21770 0.19126 0.13613 -0.08054 -0.01359 0.03220  256 PRO A N   
3656 N  N   B PRO A 233 ? 0.21997 0.18252 0.13071 -0.07106 -0.01736 0.04022  256 PRO A N   
3657 C  CA  A PRO A 233 ? 0.20676 0.18376 0.12898 -0.06084 -0.02266 0.01717  256 PRO A CA  
3658 C  CA  B PRO A 233 ? 0.20986 0.17528 0.12379 -0.06354 -0.02440 0.02743  256 PRO A CA  
3659 C  C   A PRO A 233 ? 0.21073 0.15321 0.11163 -0.03526 -0.03238 0.01231  256 PRO A C   
3660 C  C   B PRO A 233 ? 0.23156 0.14034 0.11550 -0.05004 -0.01972 0.02003  256 PRO A C   
3661 O  O   A PRO A 233 ? 0.19168 0.15885 0.10784 -0.02596 -0.05368 0.00721  256 PRO A O   
3662 O  O   B PRO A 233 ? 0.26442 0.12177 0.12864 -0.05463 -0.00690 0.03402  256 PRO A O   
3663 C  CB  A PRO A 233 ? 0.22019 0.22524 0.14456 -0.07474 -0.00589 0.00747  256 PRO A CB  
3664 C  CB  B PRO A 233 ? 0.20957 0.21808 0.12960 -0.07203 -0.01451 0.02415  256 PRO A CB  
3665 C  CG  A PRO A 233 ? 0.23198 0.24505 0.15012 -0.06321 -0.00818 0.01473  256 PRO A CG  
3666 C  CG  B PRO A 233 ? 0.22523 0.23520 0.12955 -0.05006 -0.02134 0.02795  256 PRO A CG  
3667 C  CD  A PRO A 233 ? 0.22323 0.23078 0.14442 -0.08509 -0.00099 0.02490  256 PRO A CD  
3668 C  CD  B PRO A 233 ? 0.22208 0.22075 0.13159 -0.05343 -0.00947 0.03647  256 PRO A CD  
3683 N  N   . LEU A 234 ? 0.20801 0.13945 0.10640 -0.04843 -0.01733 0.00535  257 LEU A N   
3684 C  CA  . LEU A 234 ? 0.17720 0.14263 0.11396 -0.03126 -0.01200 0.02009  257 LEU A CA  
3685 C  C   . LEU A 234 ? 0.14468 0.15615 0.11352 -0.02654 0.00459  0.02143  257 LEU A C   
3686 O  O   . LEU A 234 ? 0.15873 0.15374 0.12910 -0.03205 -0.00716 0.01460  257 LEU A O   
3687 C  CB  . LEU A 234 ? 0.19105 0.16344 0.11623 -0.01780 -0.01299 0.01923  257 LEU A CB  
3688 C  CG  . LEU A 234 ? 0.23703 0.17269 0.12746 -0.03253 -0.02031 0.00583  257 LEU A CG  
3689 C  CD1 . LEU A 234 ? 0.27928 0.21330 0.12880 -0.02076 -0.01538 -0.00066 257 LEU A CD1 
3690 C  CD2 . LEU A 234 ? 0.26588 0.17578 0.12118 -0.01928 -0.03703 -0.00892 257 LEU A CD2 
3702 N  N   . ILE A 235 ? 0.14759 0.14575 0.09728 -0.00448 -0.00213 0.00947  258 ILE A N   
3703 C  CA  . ILE A 235 ? 0.13769 0.14480 0.09125 -0.01294 -0.00040 0.01338  258 ILE A CA  
3704 C  C   . ILE A 235 ? 0.13628 0.13037 0.09609 -0.02626 0.00342  0.00625  258 ILE A C   
3705 O  O   . ILE A 235 ? 0.15705 0.13713 0.10423 0.00160  0.00770  0.01275  258 ILE A O   
3706 C  CB  . ILE A 235 ? 0.15044 0.15355 0.09364 -0.01738 -0.01049 0.00200  258 ILE A CB  
3707 C  CG1 . ILE A 235 ? 0.19525 0.17461 0.09099 -0.00599 -0.01557 0.00703  258 ILE A CG1 
3708 C  CG2 . ILE A 235 ? 0.14860 0.18266 0.09085 -0.01122 0.00213  -0.00918 258 ILE A CG2 
3709 C  CD1 . ILE A 235 ? 0.20017 0.22252 0.09055 0.00226  0.01219  -0.00255 258 ILE A CD1 
3721 N  N   . LEU A 236 ? 0.12489 0.13652 0.09243 -0.00462 0.00106  0.00266  259 LEU A N   
3722 C  CA  . LEU A 236 ? 0.12852 0.13508 0.09069 -0.00243 0.01550  -0.00711 259 LEU A CA  
3723 C  C   . LEU A 236 ? 0.12267 0.14151 0.08290 -0.00155 0.01699  0.00514  259 LEU A C   
3724 O  O   . LEU A 236 ? 0.10144 0.15064 0.10081 -0.00168 0.00312  0.00757  259 LEU A O   
3725 C  CB  . LEU A 236 ? 0.14856 0.14267 0.08971 -0.01528 0.00737  -0.00946 259 LEU A CB  
3726 C  CG  . LEU A 236 ? 0.13982 0.12858 0.09169 0.00105  -0.00586 -0.00719 259 LEU A CG  
3727 C  CD1 . LEU A 236 ? 0.15072 0.16792 0.09579 0.00188  0.00947  -0.01499 259 LEU A CD1 
3728 C  CD2 . LEU A 236 ? 0.16382 0.16875 0.09223 0.00902  0.00345  -0.01741 259 LEU A CD2 
3740 N  N   . VAL A 237 ? 0.11440 0.14436 0.07726 0.00976  0.01429  0.00875  260 VAL A N   
3741 C  CA  . VAL A 237 ? 0.11054 0.12298 0.08127 0.00944  0.01489  0.01478  260 VAL A CA  
3742 C  C   . VAL A 237 ? 0.11399 0.12508 0.08321 -0.01356 0.00478  0.00192  260 VAL A C   
3743 O  O   . VAL A 237 ? 0.12895 0.14015 0.09150 0.01487  0.01281  0.00595  260 VAL A O   
3744 C  CB  . VAL A 237 ? 0.15291 0.14851 0.09092 0.00520  -0.00669 -0.00212 260 VAL A CB  
3745 C  CG1 . VAL A 237 ? 0.16502 0.14491 0.10560 -0.02539 -0.01317 -0.01751 260 VAL A CG1 
3746 C  CG2 . VAL A 237 ? 0.17816 0.14548 0.09004 0.02063  -0.00955 -0.01036 260 VAL A CG2 
3756 N  N   . THR A 238 ? 0.11570 0.13194 0.07700 0.00758  0.00260  0.01037  261 THR A N   
3757 C  CA  . THR A 238 ? 0.11644 0.15013 0.08629 -0.00009 0.00945  0.00940  261 THR A CA  
3758 C  C   . THR A 238 ? 0.10113 0.16157 0.07856 0.00282  0.00815  0.00266  261 THR A C   
3759 O  O   . THR A 238 ? 0.10513 0.15800 0.08560 0.00408  0.00743  0.00461  261 THR A O   
3760 C  CB  . THR A 238 ? 0.12146 0.14486 0.08757 -0.00147 0.00733  0.00383  261 THR A CB  
3761 O  OG1 . THR A 238 ? 0.12158 0.15956 0.09159 -0.00826 0.01168  0.00325  261 THR A OG1 
3762 C  CG2 . THR A 238 ? 0.15510 0.16267 0.09341 -0.00151 0.00505  0.00600  261 THR A CG2 
3770 N  N   A TYR A 239 ? 0.11870 0.14411 0.08368 0.00199  0.00756  0.00076  262 TYR A N   
3771 N  N   B TYR A 239 ? 0.11337 0.13399 0.08021 -0.01245 0.00920  -0.00496 262 TYR A N   
3772 C  CA  A TYR A 239 ? 0.11422 0.16249 0.09223 0.00769  0.01722  -0.00105 262 TYR A CA  
3773 C  CA  B TYR A 239 ? 0.11931 0.12648 0.08202 -0.02333 0.01572  -0.00801 262 TYR A CA  
3774 C  C   A TYR A 239 ? 0.12730 0.15083 0.08843 0.00212  0.01668  -0.00544 262 TYR A C   
3775 C  C   B TYR A 239 ? 0.10242 0.13205 0.08198 -0.02587 0.01462  -0.01765 262 TYR A C   
3776 O  O   A TYR A 239 ? 0.12421 0.17455 0.08665 0.01080  0.00243  -0.00154 262 TYR A O   
3777 O  O   B TYR A 239 ? 0.08247 0.15517 0.08140 -0.01782 0.00948  -0.02170 262 TYR A O   
3778 C  CB  A TYR A 239 ? 0.09154 0.17958 0.09431 -0.00285 0.00113  -0.00740 262 TYR A CB  
3779 C  CB  B TYR A 239 ? 0.13298 0.10735 0.07980 -0.02895 0.01486  -0.00394 262 TYR A CB  
3780 C  CG  A TYR A 239 ? 0.09466 0.18795 0.09921 -0.03398 0.00911  0.00097  262 TYR A CG  
3781 C  CG  B TYR A 239 ? 0.16875 0.10371 0.08234 0.00863  0.01707  0.00256  262 TYR A CG  
3782 C  CD1 A TYR A 239 ? 0.12645 0.17407 0.10778 -0.00725 0.01380  -0.00237 262 TYR A CD1 
3783 C  CD1 B TYR A 239 ? 0.17748 0.12497 0.08239 0.03647  0.01466  0.00514  262 TYR A CD1 
3784 C  CD2 A TYR A 239 ? 0.10090 0.15436 0.10008 -0.00480 0.00726  -0.02076 262 TYR A CD2 
3785 C  CD2 B TYR A 239 ? 0.20900 0.11491 0.08861 -0.02324 0.01863  0.01129  262 TYR A CD2 
3786 C  CE1 A TYR A 239 ? 0.11710 0.14653 0.10947 -0.00444 0.00135  -0.00368 262 TYR A CE1 
3787 C  CE1 B TYR A 239 ? 0.19222 0.12557 0.08882 0.04423  0.01882  -0.00413 262 TYR A CE1 
3788 C  CE2 A TYR A 239 ? 0.12745 0.15149 0.09669 -0.00887 0.00973  -0.02082 262 TYR A CE2 
3789 C  CE2 B TYR A 239 ? 0.22791 0.13605 0.09162 -0.01953 0.01860  -0.00272 262 TYR A CE2 
3790 C  CZ  A TYR A 239 ? 0.09509 0.13315 0.09749 -0.00335 0.00458  -0.01234 262 TYR A CZ  
3791 C  CZ  B TYR A 239 ? 0.21526 0.14126 0.08971 0.00623  0.01927  -0.00645 262 TYR A CZ  
3792 O  OH  A TYR A 239 ? 0.10582 0.15503 0.08625 -0.00517 0.01949  -0.01712 262 TYR A OH  
3793 O  OH  B TYR A 239 ? 0.22219 0.16907 0.08903 0.01100  0.01871  -0.00308 262 TYR A OH  
3812 N  N   . PHE A 240 ? 0.12648 0.15108 0.08541 -0.00799 0.02018  -0.01348 263 PHE A N   
3813 C  CA  . PHE A 240 ? 0.13759 0.15874 0.07638 0.00467  0.01978  -0.00779 263 PHE A CA  
3814 C  C   . PHE A 240 ? 0.13840 0.16218 0.08098 -0.00357 0.01873  0.00009  263 PHE A C   
3815 O  O   . PHE A 240 ? 0.12301 0.17411 0.09242 0.00273  0.02520  -0.00216 263 PHE A O   
3816 C  CB  . PHE A 240 ? 0.14941 0.16422 0.07753 -0.01625 0.00657  0.00370  263 PHE A CB  
3817 C  CG  . PHE A 240 ? 0.14095 0.17254 0.08473 -0.00293 0.00973  -0.01366 263 PHE A CG  
3818 C  CD1 . PHE A 240 ? 0.12926 0.17287 0.08281 0.00618  0.01951  -0.03153 263 PHE A CD1 
3819 C  CD2 . PHE A 240 ? 0.13178 0.17604 0.09232 0.01006  0.01617  -0.00016 263 PHE A CD2 
3820 C  CE1 . PHE A 240 ? 0.12142 0.20725 0.08620 -0.00022 0.02052  -0.01015 263 PHE A CE1 
3821 C  CE2 . PHE A 240 ? 0.14645 0.17409 0.09596 -0.01466 0.00773  0.01210  263 PHE A CE2 
3822 C  CZ  . PHE A 240 ? 0.14379 0.22139 0.08344 -0.00626 0.02807  0.01203  263 PHE A CZ  
3833 N  N   . THR A 241 ? 0.11211 0.18226 0.08509 -0.00495 0.02622  0.00093  264 THR A N   
3834 C  CA  . THR A 241 ? 0.12438 0.17306 0.08873 -0.00667 0.01783  0.00761  264 THR A CA  
3835 C  C   . THR A 241 ? 0.12570 0.16870 0.08315 -0.01940 0.01137  0.00287  264 THR A C   
3836 O  O   . THR A 241 ? 0.16710 0.18931 0.10586 -0.00636 0.02975  0.00233  264 THR A O   
3837 C  CB  . THR A 241 ? 0.12847 0.18383 0.09481 -0.01644 0.01533  0.01087  264 THR A CB  
3838 O  OG1 . THR A 241 ? 0.15507 0.17331 0.09646 -0.01710 0.02352  0.00426  264 THR A OG1 
3839 C  CG2 . THR A 241 ? 0.14244 0.19895 0.09764 0.00198  0.01639  0.00933  264 THR A CG2 
3847 N  N   . GLN A 242 ? 0.16155 0.17335 0.08411 -0.00164 0.03285  0.01153  265 GLN A N   
3848 C  CA  . GLN A 242 ? 0.14898 0.18685 0.08718 -0.01167 0.02531  0.01104  265 GLN A CA  
3849 C  C   . GLN A 242 ? 0.15266 0.21323 0.11216 -0.00375 0.04777  0.02527  265 GLN A C   
3850 O  O   . GLN A 242 ? 0.17598 0.20524 0.10988 -0.02990 0.03835  0.01751  265 GLN A O   
3851 C  CB  . GLN A 242 ? 0.13976 0.20001 0.08628 -0.00957 0.02567  0.01159  265 GLN A CB  
3852 C  CG  . GLN A 242 ? 0.16103 0.22935 0.09378 0.00946  0.01473  0.00966  265 GLN A CG  
3853 C  CD  . GLN A 242 ? 0.16616 0.21686 0.09013 -0.01309 0.00644  -0.00778 265 GLN A CD  
3854 O  OE1 . GLN A 242 ? 0.19089 0.27486 0.09160 -0.00752 0.02309  -0.00467 265 GLN A OE1 
3855 N  NE2 . GLN A 242 ? 0.16035 0.19897 0.08917 0.00121  -0.00154 0.00588  265 GLN A NE2 
3864 N  N   . PRO A 243 ? 0.16553 0.22656 0.11985 -0.00083 0.06136  0.03980  266 PRO A N   
3865 C  CA  . PRO A 243 ? 0.16505 0.25708 0.14163 -0.02661 0.05713  0.05607  266 PRO A CA  
3866 C  C   . PRO A 243 ? 0.15971 0.23982 0.13776 -0.03044 0.05882  0.03366  266 PRO A C   
3867 O  O   . PRO A 243 ? 0.19597 0.26771 0.15991 -0.06207 0.04231  0.02262  266 PRO A O   
3868 C  CB  . PRO A 243 ? 0.19471 0.32009 0.15927 -0.02761 0.06117  0.04357  266 PRO A CB  
3869 C  CG  . PRO A 243 ? 0.18590 0.34523 0.15242 0.00429  0.07069  0.02729  266 PRO A CG  
3870 C  CD  . PRO A 243 ? 0.18304 0.26705 0.13105 0.00012  0.06700  0.02109  266 PRO A CD  
3878 N  N   . GLN A 244 ? 0.17198 0.24301 0.12996 -0.02215 0.04283  0.02325  267 GLN A N   
3879 C  CA  . GLN A 244 ? 0.21572 0.19962 0.11829 -0.03657 0.05137  0.02213  267 GLN A CA  
3880 C  C   . GLN A 244 ? 0.21991 0.19981 0.11138 -0.03013 0.04858  0.01930  267 GLN A C   
3881 O  O   . GLN A 244 ? 0.20731 0.20025 0.10805 -0.02666 0.04764  0.00526  267 GLN A O   
3882 C  CB  . GLN A 244 ? 0.23011 0.18624 0.11850 -0.00573 0.06254  0.00113  267 GLN A CB  
3883 C  CG  . GLN A 244 ? 0.23844 0.22498 0.12889 0.00698  0.07015  0.01673  267 GLN A CG  
3884 C  CD  . GLN A 244 ? 0.20828 0.23408 0.13882 0.03757  0.06359  0.00019  267 GLN A CD  
3885 O  OE1 . GLN A 244 ? 0.21727 0.21086 0.13630 0.02129  0.06170  -0.00478 267 GLN A OE1 
3886 N  NE2 . GLN A 244 ? 0.19043 0.27490 0.15062 0.06020  0.07058  -0.00290 267 GLN A NE2 
3895 N  N   . PRO A 245 ? 0.23362 0.19925 0.12416 -0.04978 0.05305  0.01196  268 PRO A N   
3896 C  CA  . PRO A 245 ? 0.21758 0.20589 0.13478 -0.05272 0.04959  -0.01893 268 PRO A CA  
3897 C  C   . PRO A 245 ? 0.21207 0.19665 0.13366 -0.02562 0.05206  -0.00880 268 PRO A C   
3898 O  O   . PRO A 245 ? 0.22648 0.22187 0.14436 -0.02379 0.06684  -0.00177 268 PRO A O   
3899 C  CB  . PRO A 245 ? 0.26780 0.21038 0.15115 -0.05693 0.05781  -0.02713 268 PRO A CB  
3900 C  CG  . PRO A 245 ? 0.31058 0.22069 0.14800 -0.08286 0.08051  -0.01926 268 PRO A CG  
3901 C  CD  . PRO A 245 ? 0.26625 0.20803 0.13275 -0.05358 0.07230  -0.00070 268 PRO A CD  
3909 N  N   . LYS A 246 ? 0.20469 0.19967 0.14499 -0.02143 0.05268  0.00496  269 LYS A N   
3910 C  CA  . LYS A 246 ? 0.19899 0.19518 0.15880 -0.00247 0.04855  -0.00468 269 LYS A CA  
3911 C  C   . LYS A 246 ? 0.18500 0.18866 0.14621 -0.00978 0.03325  0.00271  269 LYS A C   
3912 O  O   . LYS A 246 ? 0.22470 0.21813 0.16435 0.00355  0.01488  0.02858  269 LYS A O   
3913 C  CB  . LYS A 246 ? 0.24616 0.19598 0.18377 0.00829  0.03897  -0.00600 269 LYS A CB  
3914 C  CG  . LYS A 246 ? 0.34207 0.21316 0.21808 0.02811  0.02802  0.01394  269 LYS A CG  
3915 C  CD  . LYS A 246 ? 0.43210 0.26469 0.24284 0.02529  0.01993  0.00875  269 LYS A CD  
3916 C  CE  . LYS A 246 ? 0.51709 0.35531 0.27118 0.02817  0.01213  0.00855  269 LYS A CE  
3917 N  NZ  . LYS A 246 ? 0.56438 0.42176 0.30344 0.01733  0.00198  0.02602  269 LYS A NZ  
3931 N  N   . ALA A 247 ? 0.17647 0.20227 0.12475 -0.02501 0.03301  0.01596  270 ALA A N   
3932 C  CA  . ALA A 247 ? 0.20375 0.20636 0.11343 -0.02050 0.03052  0.00901  270 ALA A CA  
3933 C  C   . ALA A 247 ? 0.19240 0.21145 0.12002 -0.03137 0.02462  0.02314  270 ALA A C   
3934 O  O   . ALA A 247 ? 0.19121 0.22750 0.12918 -0.01694 0.02241  0.03407  270 ALA A O   
3935 C  CB  . ALA A 247 ? 0.22013 0.16454 0.11452 -0.01090 0.02829  -0.01099 270 ALA A CB  
3941 N  N   A GLU A 248 ? 0.19958 0.20881 0.13227 -0.03753 0.01148  0.03554  271 GLU A N   
3942 N  N   B GLU A 248 ? 0.18908 0.21177 0.12724 -0.03529 0.02078  0.01844  271 GLU A N   
3943 C  CA  A GLU A 248 ? 0.22300 0.21521 0.14931 -0.03288 -0.00388 0.06134  271 GLU A CA  
3944 C  CA  B GLU A 248 ? 0.21472 0.23033 0.14241 -0.03253 0.00771  0.03435  271 GLU A CA  
3945 C  C   A GLU A 248 ? 0.18030 0.19522 0.15135 0.00005  -0.00498 0.04705  271 GLU A C   
3946 C  C   B GLU A 248 ? 0.17608 0.20286 0.14388 -0.01608 0.00873  0.02024  271 GLU A C   
3947 O  O   A GLU A 248 ? 0.16916 0.20141 0.14996 0.01331  -0.01648 0.04717  271 GLU A O   
3948 O  O   B GLU A 248 ? 0.18983 0.21251 0.14192 -0.04100 0.01704  -0.00405 271 GLU A O   
3949 C  CB  A GLU A 248 ? 0.29357 0.26593 0.16893 -0.03527 -0.01567 0.09390  271 GLU A CB  
3950 C  CB  B GLU A 248 ? 0.28333 0.30590 0.16078 -0.02077 -0.00573 0.05581  271 GLU A CB  
3951 C  CG  A GLU A 248 ? 0.35282 0.31606 0.18958 -0.03739 -0.01868 0.10684  271 GLU A CG  
3952 C  CG  B GLU A 248 ? 0.34997 0.38672 0.17891 -0.02310 -0.00931 0.04380  271 GLU A CG  
3953 C  CD  A GLU A 248 ? 0.41228 0.37221 0.21302 -0.06063 -0.01925 0.09674  271 GLU A CD  
3954 C  CD  B GLU A 248 ? 0.41370 0.44817 0.20513 0.00826  -0.02601 0.01683  271 GLU A CD  
3955 O  OE1 A GLU A 248 ? 0.42854 0.38473 0.22330 -0.08560 -0.00962 0.10375  271 GLU A OE1 
3956 O  OE1 B GLU A 248 ? 0.44647 0.47552 0.22015 0.03919  -0.05532 0.01974  271 GLU A OE1 
3957 O  OE2 A GLU A 248 ? 0.44046 0.41520 0.22478 -0.05648 -0.02383 0.08144  271 GLU A OE2 
3958 O  OE2 B GLU A 248 ? 0.42572 0.45782 0.20469 0.00244  -0.00669 -0.00023 271 GLU A OE2 
3971 N  N   . SER A 249 ? 0.18411 0.19418 0.16201 -0.01134 0.01284  0.02901  272 SER A N   
3972 C  CA  . SER A 249 ? 0.19444 0.22364 0.15812 -0.01796 0.00817  0.01294  272 SER A CA  
3973 C  C   . SER A 249 ? 0.19268 0.20807 0.12761 -0.00923 0.00224  0.01154  272 SER A C   
3974 O  O   . SER A 249 ? 0.22847 0.21909 0.13574 -0.02745 -0.03203 0.03949  272 SER A O   
3975 C  CB  . SER A 249 ? 0.24327 0.29295 0.18750 -0.02956 0.04683  0.01549  272 SER A CB  
3976 O  OG  . SER A 249 ? 0.31002 0.34107 0.21968 -0.02791 0.04334  -0.00428 272 SER A OG  
3982 N  N   . ARG A 250 ? 0.17908 0.21354 0.09343 -0.02417 -0.01338 0.02460  273 ARG A N   
3983 C  CA  . ARG A 250 ? 0.17366 0.22034 0.11290 -0.04181 -0.00944 0.01930  273 ARG A CA  
3984 C  C   . ARG A 250 ? 0.13609 0.20373 0.09750 -0.02347 -0.01525 0.02157  273 ARG A C   
3985 O  O   . ARG A 250 ? 0.16062 0.19909 0.09372 -0.01036 -0.01125 0.02010  273 ARG A O   
3986 C  CB  . ARG A 250 ? 0.17283 0.23191 0.10584 -0.04591 0.00943  0.01386  273 ARG A CB  
3987 C  CG  . ARG A 250 ? 0.19554 0.24079 0.11038 -0.01743 0.00354  0.01521  273 ARG A CG  
3988 C  CD  . ARG A 250 ? 0.22993 0.27951 0.10947 -0.05965 0.00886  0.01763  273 ARG A CD  
3989 N  NE  . ARG A 250 ? 0.26352 0.31835 0.10514 -0.05796 0.02613  0.00939  273 ARG A NE  
3990 C  CZ  . ARG A 250 ? 0.29590 0.33353 0.11975 -0.09373 0.04112  0.00876  273 ARG A CZ  
3991 N  NH1 . ARG A 250 ? 0.28551 0.35889 0.13222 -0.05961 0.02124  0.00152  273 ARG A NH1 
3992 N  NH2 . ARG A 250 ? 0.34422 0.35353 0.12976 -0.06773 0.04065  -0.00517 273 ARG A NH2 
4006 N  N   A ARG A 251 ? 0.13408 0.19782 0.10288 -0.00821 -0.00422 0.02307  274 ARG A N   
4007 N  N   B ARG A 251 ? 0.13780 0.19844 0.10399 -0.00735 -0.00789 0.02718  274 ARG A N   
4008 C  CA  A ARG A 251 ? 0.13900 0.19381 0.11064 -0.02611 -0.01029 0.02346  274 ARG A CA  
4009 C  CA  B ARG A 251 ? 0.14412 0.19291 0.11170 -0.02148 -0.01241 0.03043  274 ARG A CA  
4010 C  C   A ARG A 251 ? 0.14658 0.21087 0.11017 -0.01541 -0.01222 0.01523  274 ARG A C   
4011 C  C   B ARG A 251 ? 0.15146 0.20974 0.11075 -0.01227 -0.01570 0.01798  274 ARG A C   
4012 O  O   A ARG A 251 ? 0.15453 0.19317 0.10800 -0.02456 -0.00551 0.01736  274 ARG A O   
4013 O  O   B ARG A 251 ? 0.15892 0.19443 0.10911 -0.01448 -0.01383 0.01832  274 ARG A O   
4014 C  CB  A ARG A 251 ? 0.16021 0.21387 0.13297 -0.03917 -0.00982 0.02337  274 ARG A CB  
4015 C  CB  B ARG A 251 ? 0.15930 0.20766 0.13030 -0.03242 -0.01233 0.03819  274 ARG A CB  
4016 C  CG  A ARG A 251 ? 0.16064 0.22184 0.15361 -0.03094 -0.00768 0.01473  274 ARG A CG  
4017 C  CG  B ARG A 251 ? 0.15492 0.21430 0.14420 -0.03222 -0.01258 0.03340  274 ARG A CG  
4018 C  CD  A ARG A 251 ? 0.21513 0.24676 0.19021 -0.03992 0.01121  0.01026  274 ARG A CD  
4019 C  CD  B ARG A 251 ? 0.17733 0.21951 0.16409 -0.04061 0.01344  0.03085  274 ARG A CD  
4020 N  NE  A ARG A 251 ? 0.25508 0.27488 0.22822 -0.02954 0.01909  0.01178  274 ARG A NE  
4021 N  NE  B ARG A 251 ? 0.21365 0.26311 0.18288 -0.02604 0.03015  0.03594  274 ARG A NE  
4022 C  CZ  A ARG A 251 ? 0.28699 0.28517 0.24834 -0.02262 0.02294  0.00508  274 ARG A CZ  
4023 C  CZ  B ARG A 251 ? 0.25749 0.31696 0.19591 -0.00574 0.05104  0.03841  274 ARG A CZ  
4024 N  NH1 A ARG A 251 ? 0.28166 0.27750 0.25612 -0.02742 0.01805  0.00453  274 ARG A NH1 
4025 N  NH1 B ARG A 251 ? 0.23863 0.33718 0.19629 0.02227  0.06088  0.03678  274 ARG A NH1 
4026 N  NH2 A ARG A 251 ? 0.32355 0.29994 0.26084 -0.01567 0.02030  -0.00733 274 ARG A NH2 
4027 N  NH2 B ARG A 251 ? 0.29673 0.32424 0.20286 -0.01381 0.05171  0.05701  274 ARG A NH2 
4054 N  N   . ASP A 252 ? 0.18288 0.21201 0.10827 -0.02840 -0.02363 0.01191  275 ASP A N   
4055 C  CA  . ASP A 252 ? 0.18529 0.23239 0.10013 -0.03064 -0.02522 0.01655  275 ASP A CA  
4056 C  C   . ASP A 252 ? 0.17400 0.22367 0.08610 -0.04487 -0.01518 0.01101  275 ASP A C   
4057 O  O   . ASP A 252 ? 0.18997 0.20536 0.09595 -0.04338 -0.00624 0.00006  275 ASP A O   
4058 C  CB  . ASP A 252 ? 0.22468 0.26030 0.10730 -0.05494 -0.01460 0.01556  275 ASP A CB  
4059 C  CG  . ASP A 252 ? 0.28677 0.27232 0.12111 -0.05969 0.01261  0.01010  275 ASP A CG  
4060 O  OD1 . ASP A 252 ? 0.27117 0.23931 0.11268 -0.06254 0.00903  0.01860  275 ASP A OD1 
4061 O  OD2 . ASP A 252 ? 0.34357 0.34295 0.16852 -0.10077 0.04373  -0.03038 275 ASP A OD2 
4066 N  N   . VAL A 253 ? 0.16556 0.20547 0.08534 -0.02329 -0.00544 0.00747  276 VAL A N   
4067 C  CA  . VAL A 253 ? 0.16562 0.20041 0.10039 -0.02904 0.00650  0.00713  276 VAL A CA  
4068 C  C   . VAL A 253 ? 0.13246 0.18316 0.09649 -0.02453 0.00528  -0.01728 276 VAL A C   
4069 O  O   . VAL A 253 ? 0.15935 0.18265 0.10660 -0.01447 0.01414  -0.01484 276 VAL A O   
4070 C  CB  . VAL A 253 ? 0.14933 0.21390 0.10717 0.00079  0.01512  0.00592  276 VAL A CB  
4071 C  CG1 . VAL A 253 ? 0.15138 0.20271 0.11377 -0.00128 0.02075  0.00244  276 VAL A CG1 
4072 C  CG2 . VAL A 253 ? 0.17118 0.25216 0.12138 -0.02593 0.02840  0.01719  276 VAL A CG2 
4082 N  N   . LEU A 254 ? 0.12218 0.16139 0.09712 -0.00957 0.00797  -0.00188 277 LEU A N   
4083 C  CA  . LEU A 254 ? 0.13083 0.17316 0.08266 -0.02272 -0.00224 -0.00688 277 LEU A CA  
4084 C  C   . LEU A 254 ? 0.12881 0.17715 0.08217 -0.00624 -0.00061 -0.01577 277 LEU A C   
4085 O  O   . LEU A 254 ? 0.14263 0.16425 0.08230 0.00180  -0.00540 -0.00368 277 LEU A O   
4086 C  CB  . LEU A 254 ? 0.14897 0.17017 0.08962 -0.00921 -0.00967 -0.00330 277 LEU A CB  
4087 C  CG  . LEU A 254 ? 0.13055 0.16326 0.07884 -0.02464 -0.00053 -0.00099 277 LEU A CG  
4088 C  CD1 . LEU A 254 ? 0.14472 0.16041 0.07830 -0.00302 -0.00511 -0.00413 277 LEU A CD1 
4089 C  CD2 . LEU A 254 ? 0.13123 0.17622 0.08661 -0.00263 -0.00626 0.00869  277 LEU A CD2 
4101 N  N   . ALA A 255 ? 0.12655 0.18502 0.09047 -0.02746 -0.01510 -0.01513 278 ALA A N   
4102 C  CA  . ALA A 255 ? 0.12225 0.19729 0.09591 -0.02050 -0.01102 -0.01864 278 ALA A CA  
4103 C  C   . ALA A 255 ? 0.14446 0.18298 0.09817 -0.02448 -0.01062 -0.01396 278 ALA A C   
4104 O  O   . ALA A 255 ? 0.15801 0.18568 0.10620 -0.01311 -0.01107 -0.00848 278 ALA A O   
4105 C  CB  . ALA A 255 ? 0.13456 0.19875 0.08706 -0.03561 -0.01176 -0.01925 278 ALA A CB  
4111 N  N   . SER A 256 ? 0.15469 0.18035 0.08576 -0.02657 0.00527  -0.00299 279 SER A N   
4112 C  CA  . SER A 256 ? 0.16848 0.19798 0.09197 -0.02210 0.00896  -0.01979 279 SER A CA  
4113 C  C   . SER A 256 ? 0.16856 0.18214 0.10266 -0.02218 0.01319  -0.01769 279 SER A C   
4114 O  O   . SER A 256 ? 0.17063 0.18361 0.11233 -0.01478 0.00665  -0.03110 279 SER A O   
4115 C  CB  . SER A 256 ? 0.20845 0.24764 0.09165 0.00552  0.02186  -0.00605 279 SER A CB  
4116 O  OG  . SER A 256 ? 0.26646 0.32629 0.10912 0.02085  0.01383  0.01886  279 SER A OG  
4122 N  N   . ALA A 257 ? 0.16241 0.19021 0.10366 -0.02017 -0.00473 -0.02484 280 ALA A N   
4123 C  CA  . ALA A 257 ? 0.14639 0.20129 0.09712 -0.01433 0.01076  -0.01991 280 ALA A CA  
4124 C  C   . ALA A 257 ? 0.15209 0.17096 0.09523 -0.00557 -0.00175 -0.01263 280 ALA A C   
4125 O  O   . ALA A 257 ? 0.18952 0.17389 0.10148 0.00985  -0.00287 -0.01747 280 ALA A O   
4126 C  CB  . ALA A 257 ? 0.16498 0.19118 0.10784 -0.01547 0.00161  -0.02902 280 ALA A CB  
4132 N  N   . ALA A 258 ? 0.13614 0.18083 0.10468 -0.00313 0.00629  -0.01062 281 ALA A N   
4133 C  CA  . ALA A 258 ? 0.13030 0.17160 0.08842 -0.00426 -0.00035 -0.01719 281 ALA A CA  
4134 C  C   . ALA A 258 ? 0.13248 0.17878 0.10390 -0.00382 -0.01621 -0.01365 281 ALA A C   
4135 O  O   . ALA A 258 ? 0.18095 0.16663 0.11638 -0.00865 -0.00538 -0.01516 281 ALA A O   
4136 C  CB  . ALA A 258 ? 0.13130 0.19837 0.09602 -0.01205 0.00450  -0.01301 281 ALA A CB  
4142 N  N   . LYS A 259 ? 0.16706 0.17582 0.10519 -0.01315 -0.02249 -0.02633 282 LYS A N   
4143 C  CA  . LYS A 259 ? 0.20429 0.18294 0.11529 -0.00718 -0.01198 -0.02685 282 LYS A CA  
4144 C  C   . LYS A 259 ? 0.20603 0.16342 0.12974 -0.02250 -0.00051 -0.03019 282 LYS A C   
4145 O  O   . LYS A 259 ? 0.21778 0.16712 0.14417 -0.01092 -0.00486 -0.03207 282 LYS A O   
4146 C  CB  . LYS A 259 ? 0.21813 0.21191 0.12167 -0.01725 -0.02749 -0.03404 282 LYS A CB  
4147 C  CG  . LYS A 259 ? 0.28396 0.27643 0.14228 -0.01813 -0.04667 -0.04650 282 LYS A CG  
4148 C  CD  . LYS A 259 ? 0.38608 0.40970 0.16041 0.00117  -0.05854 -0.06390 282 LYS A CD  
4149 C  CE  . LYS A 259 ? 0.48048 0.54042 0.18640 0.00562  -0.04624 -0.06152 282 LYS A CE  
4150 N  NZ  . LYS A 259 ? 0.55613 0.64767 0.21028 0.02259  -0.03416 -0.05610 282 LYS A NZ  
4164 N  N   . ILE A 260 ? 0.17678 0.19088 0.12412 -0.01938 0.00250  -0.03101 283 ILE A N   
4165 C  CA  . ILE A 260 ? 0.19750 0.19776 0.12715 0.00719  0.01301  -0.04177 283 ILE A CA  
4166 C  C   . ILE A 260 ? 0.19765 0.15876 0.13822 -0.00651 -0.01340 -0.03993 283 ILE A C   
4167 O  O   . ILE A 260 ? 0.24030 0.17359 0.14451 0.00643  -0.00345 -0.04306 283 ILE A O   
4168 C  CB  . ILE A 260 ? 0.17916 0.22870 0.13013 0.00595  0.02427  -0.04805 283 ILE A CB  
4169 C  CG1 . ILE A 260 ? 0.20373 0.21919 0.13611 -0.01559 0.02359  -0.03277 283 ILE A CG1 
4170 C  CG2 . ILE A 260 ? 0.22663 0.21827 0.13701 -0.00066 0.01911  -0.03636 283 ILE A CG2 
4171 C  CD1 . ILE A 260 ? 0.21101 0.21649 0.14887 0.00616  0.01454  -0.01903 283 ILE A CD1 
4183 N  N   . VAL A 261 ? 0.19159 0.17793 0.13393 0.01596  -0.01538 -0.03627 284 VAL A N   
4184 C  CA  . VAL A 261 ? 0.19947 0.17988 0.15068 0.01778  -0.01660 -0.02655 284 VAL A CA  
4185 C  C   . VAL A 261 ? 0.20343 0.18772 0.17139 0.02576  -0.02149 -0.02437 284 VAL A C   
4186 O  O   . VAL A 261 ? 0.26671 0.20133 0.18553 0.01672  -0.03798 0.00953  284 VAL A O   
4187 C  CB  . VAL A 261 ? 0.20223 0.16807 0.14903 0.01486  -0.01801 -0.01047 284 VAL A CB  
4188 C  CG1 . VAL A 261 ? 0.20553 0.17944 0.15074 0.00115  -0.01463 -0.01648 284 VAL A CG1 
4189 C  CG2 . VAL A 261 ? 0.21965 0.15965 0.13338 0.03134  -0.02363 -0.02460 284 VAL A CG2 
4199 N  N   . THR A 262 ? 0.19609 0.17757 0.18949 0.00581  -0.02130 -0.00472 285 THR A N   
4200 C  CA  . THR A 262 ? 0.22598 0.20198 0.22496 -0.01683 -0.00790 0.00909  285 THR A CA  
4201 C  C   . THR A 262 ? 0.31088 0.21033 0.26669 -0.01077 -0.01127 -0.00385 285 THR A C   
4202 O  O   . THR A 262 ? 0.32845 0.24533 0.27702 -0.04316 -0.00103 0.01531  285 THR A O   
4203 C  CB  . THR A 262 ? 0.19972 0.19019 0.22071 -0.01326 -0.01332 0.03443  285 THR A CB  
4204 O  OG1 . THR A 262 ? 0.20936 0.17635 0.21212 -0.01769 -0.02984 0.02968  285 THR A OG1 
4205 C  CG2 . THR A 262 ? 0.19851 0.22125 0.21459 0.00599  0.00533  0.01953  285 THR A CG2 
4213 N  N   . ASP A 263 ? 0.39397 0.19149 0.29789 -0.02199 -0.00735 -0.05119 286 ASP A N   
4214 C  CA  . ASP A 263 ? 0.48375 0.27760 0.34610 -0.04192 -0.00631 -0.06702 286 ASP A CA  
4215 C  C   . ASP A 263 ? 0.55348 0.31058 0.37828 -0.05846 -0.01021 -0.04732 286 ASP A C   
4216 O  O   . ASP A 263 ? 0.57229 0.31851 0.38855 -0.03970 -0.01598 -0.03337 286 ASP A O   
4217 C  CB  . ASP A 263 ? 0.51759 0.40077 0.36413 -0.03836 0.00022  -0.09611 286 ASP A CB  
4218 C  CG  . ASP A 263 ? 0.53924 0.52900 0.38167 -0.04707 0.00045  -0.10262 286 ASP A CG  
4219 O  OD1 . ASP A 263 ? 0.53960 0.56439 0.38609 -0.06597 -0.00675 -0.10974 286 ASP A OD1 
4220 O  OD2 . ASP A 263 ? 0.56103 0.58908 0.39297 -0.03471 -0.00210 -0.09748 286 ASP A OD2 
4225 N  N   . GLY A 264 ? 0.62416 0.33665 0.39580 -0.05933 0.00381  -0.03421 287 GLY A N   
4226 C  CA  . GLY A 264 ? 0.67894 0.37539 0.41130 -0.05491 0.02066  -0.02537 287 GLY A CA  
4227 C  C   . GLY A 264 ? 0.71670 0.40590 0.42625 -0.05910 0.03515  -0.00622 287 GLY A C   
4228 O  O   . GLY A 264 ? 0.73801 0.40512 0.43798 -0.08379 0.03288  0.00694  287 GLY A O   
4232 N  N   . LEU A 265 ? 0.71914 0.40511 0.42483 -0.05251 0.05156  -0.00731 288 LEU A N   
4233 C  CA  . LEU A 265 ? 0.72418 0.43230 0.42392 -0.03258 0.06452  -0.00723 288 LEU A CA  
4234 C  C   . LEU A 265 ? 0.70772 0.47203 0.42466 -0.02103 0.07044  -0.00763 288 LEU A C   
4235 O  O   . LEU A 265 ? 0.68805 0.47014 0.42270 -0.03141 0.06506  -0.01096 288 LEU A O   
4236 C  CB  . LEU A 265 ? 0.74142 0.40165 0.41967 -0.01113 0.07108  -0.01012 288 LEU A CB  
4237 C  CG  . LEU A 265 ? 0.75815 0.36539 0.41557 -0.00434 0.07562  -0.01966 288 LEU A CG  
4238 C  CD1 . LEU A 265 ? 0.76293 0.35251 0.41295 -0.00970 0.08635  -0.01279 288 LEU A CD1 
4239 C  CD2 . LEU A 265 ? 0.76901 0.35344 0.41623 0.01954  0.06658  -0.03400 288 LEU A CD2 
4240 O  OXT . LEU A 265 ? 0.69549 0.48505 0.42197 0.00555  0.07908  -0.00805 288 LEU A OXT 
4252 C  C12 A XR9 B .   ? 0.13965 0.15016 0.12386 0.00870  0.04959  0.02527  301 XR9 A C12 
4253 C  C12 B XR9 B .   ? 0.15112 0.18387 0.13961 0.00332  0.00616  0.00338  301 XR9 A C12 
4254 C  C11 A XR9 B .   ? 0.16533 0.16934 0.12849 0.02864  0.04317  0.02721  301 XR9 A C11 
4255 C  C11 B XR9 B .   ? 0.13863 0.20389 0.12542 0.00099  0.02137  -0.01991 301 XR9 A C11 
4256 C  C9  A XR9 B .   ? 0.18746 0.17781 0.12885 0.01868  0.04439  0.03082  301 XR9 A C9  
4257 C  C9  B XR9 B .   ? 0.20106 0.27009 0.14408 0.00690  -0.02444 0.00382  301 XR9 A C9  
4258 C  C7  A XR9 B .   ? 0.16722 0.18324 0.13349 -0.02774 0.04366  0.03379  301 XR9 A C7  
4259 C  C7  B XR9 B .   ? 0.17326 0.20032 0.14772 -0.01818 -0.00860 0.00456  301 XR9 A C7  
4260 C  C4  A XR9 B .   ? 0.20565 0.21714 0.13586 -0.04405 0.02925  0.02582  301 XR9 A C4  
4261 C  C4  B XR9 B .   ? 0.18881 0.20388 0.15251 -0.00915 0.01380  0.01106  301 XR9 A C4  
4262 N  N6  A XR9 B .   ? 0.30507 0.31407 0.15666 -0.04410 0.01957  0.02867  301 XR9 A N6  
4263 N  N6  B XR9 B .   ? 0.32786 0.26231 0.16742 -0.00261 0.01463  0.06337  301 XR9 A N6  
4264 B  B2  A XR9 B .   ? 0.14550 0.14788 0.12250 -0.01583 0.04199  0.00737  301 XR9 A B2  
4265 B  B2  B XR9 B .   ? 0.11332 0.16444 0.13190 -0.00314 0.01634  0.00552  301 XR9 A B2  
4266 C  C10 A XR9 B .   ? 0.16666 0.18624 0.13007 0.02617  0.04534  0.02559  301 XR9 A C10 
4267 C  C10 B XR9 B .   ? 0.19033 0.24563 0.14511 0.02101  -0.00616 -0.01049 301 XR9 A C10 
4268 C  C5  A XR9 B .   ? 0.25170 0.27098 0.14401 -0.04515 0.03174  0.03115  301 XR9 A C5  
4269 C  C5  B XR9 B .   ? 0.26380 0.23184 0.16199 -0.00684 0.02380  0.02829  301 XR9 A C5  
4270 C  C8  A XR9 B .   ? 0.17516 0.18452 0.13180 0.01440  0.04928  0.03769  301 XR9 A C8  
4271 C  C8  B XR9 B .   ? 0.18646 0.23400 0.14484 0.00344  -0.01408 0.00173  301 XR9 A C8  
4272 O  O1  A XR9 B .   ? 0.15445 0.12129 0.12675 -0.01396 0.07673  -0.00151 301 XR9 A O1  
4273 O  O1  B XR9 B .   ? 0.12601 0.14705 0.13235 -0.00266 0.01868  0.02144  301 XR9 A O1  
4274 O  O3  A XR9 B .   ? 0.20415 0.18404 0.12914 -0.03677 0.02324  0.01176  301 XR9 A O3  
4275 O  O3  B XR9 B .   ? 0.14844 0.20706 0.15013 0.01076  0.02695  0.00751  301 XR9 A O3  
4288 S  S   . DMS C .   ? 0.71040 0.56434 0.77627 -0.00695 0.35508  0.11233  302 DMS A S   
4289 O  O   . DMS C .   ? 0.69450 0.55369 0.77352 -0.00567 0.36442  0.11572  302 DMS A O   
4290 C  C1  . DMS C .   ? 0.69818 0.57255 0.77373 0.01474  0.36731  0.11013  302 DMS A C1  
4291 C  C2  . DMS C .   ? 0.69419 0.55817 0.77097 -0.01809 0.37267  0.10913  302 DMS A C2  
4298 S  S   . SO4 D .   ? 0.87415 0.79840 1.00553 -0.14153 -0.31668 -0.36554 303 SO4 A S   
4299 O  O1  . SO4 D .   ? 0.87320 0.81002 1.00229 -0.13760 -0.32596 -0.36341 303 SO4 A O1  
4300 O  O2  . SO4 D .   ? 0.89022 0.80577 1.01582 -0.14378 -0.31529 -0.37405 303 SO4 A O2  
4301 O  O3  . SO4 D .   ? 0.86219 0.79654 0.99732 -0.15030 -0.31133 -0.35931 303 SO4 A O3  
4302 O  O4  . SO4 D .   ? 0.88052 0.80567 1.01225 -0.13950 -0.31711 -0.37208 303 SO4 A O4  
4303 S  S   . SO4 E .   ? 0.19078 0.20534 0.17379 -0.00634 -0.01056 -0.00567 304 SO4 A S   
4304 O  O1  . SO4 E .   ? 0.16991 0.17085 0.18723 -0.01459 0.03714  0.03550  304 SO4 A O1  
4305 O  O2  . SO4 E .   ? 0.18221 0.28131 0.16873 -0.00090 -0.00379 0.02488  304 SO4 A O2  
4306 O  O3  . SO4 E .   ? 0.20217 0.17850 0.17884 0.05077  -0.09976 -0.04284 304 SO4 A O3  
4307 O  O4  . SO4 E .   ? 0.19980 0.17538 0.16954 0.00423  -0.00977 -0.01920 304 SO4 A O4  
4308 S  S   A SO4 F .   ? 0.68643 1.09112 1.18096 -0.01222 0.29111  -0.10967 305 SO4 A S   
4309 S  S   B SO4 F .   ? 0.68027 1.12491 1.17255 -0.03533 0.28036  -0.11580 305 SO4 A S   
4310 O  O1  A SO4 F .   ? 0.68492 1.09023 1.18115 -0.01527 0.29160  -0.10930 305 SO4 A O1  
4311 O  O1  B SO4 F .   ? 0.68055 1.12374 1.17262 -0.03971 0.28004  -0.11553 305 SO4 A O1  
4312 O  O2  A SO4 F .   ? 0.69165 1.09341 1.18090 -0.01274 0.28797  -0.10874 305 SO4 A O2  
4313 O  O2  B SO4 F .   ? 0.68432 1.12472 1.17244 -0.04035 0.27783  -0.11526 305 SO4 A O2  
4314 O  O3  A SO4 F .   ? 0.68379 1.08877 1.18082 -0.01344 0.29153  -0.11098 305 SO4 A O3  
4315 O  O3  B SO4 F .   ? 0.68165 1.12411 1.17274 -0.03260 0.28332  -0.11560 305 SO4 A O3  
4316 O  O4  A SO4 F .   ? 0.68721 1.09044 1.18116 -0.01519 0.29126  -0.11027 305 SO4 A O4  
4317 O  O4  B SO4 F .   ? 0.68108 1.12442 1.17280 -0.03884 0.27833  -0.11679 305 SO4 A O4  
4318 S  S   . SO4 G .   ? 1.15734 0.82139 0.85481 0.22622  0.00345  -0.11321 306 SO4 A S   
4319 O  O1  . SO4 G .   ? 1.15711 0.81958 0.85497 0.22727  0.00025  -0.11552 306 SO4 A O1  
4320 O  O2  . SO4 G .   ? 1.15867 0.82426 0.85517 0.22327  0.00626  -0.10974 306 SO4 A O2  
4321 O  O3  . SO4 G .   ? 1.15458 0.81749 0.85396 0.23097  0.00697  -0.12293 306 SO4 A O3  
4322 O  O4  . SO4 G .   ? 1.15417 0.81837 0.85518 0.22864  0.00339  -0.10727 306 SO4 A O4  
4323 CL CL  . CL  H .   ? 0.22366 0.19629 0.13617 -0.00389 -0.04728 0.00726  307 CL  A CL  
4324 NA NA  . NA  I .   ? 0.21081 0.23966 0.14542 -0.03369 -0.00556 0.00028  308 NA  A NA  
4325 NA NA  . NA  J .   ? 0.20426 0.23646 0.13666 -0.01382 -0.01285 -0.00636 309 NA  A NA  
4326 O  O   . HOH K .   ? 0.70536 0.65261 0.85749 -0.00296 0.13856  -0.22532 401 HOH A O   
4327 O  O   . HOH K .   ? 0.66585 0.96107 0.30220 -0.22372 -0.03042 -0.05577 402 HOH A O   
4328 O  O   . HOH K .   ? 0.72949 0.52036 0.60568 -0.14051 -0.19900 -0.22933 403 HOH A O   
4329 O  O   . HOH K .   ? 0.45386 0.36402 0.44153 -0.12944 -0.00343 0.08944  404 HOH A O   
4330 O  O   . HOH K .   ? 1.09672 0.57639 0.65271 -0.21532 0.36864  -0.01393 405 HOH A O   
4331 O  O   . HOH K .   ? 0.89821 0.46682 0.86251 0.21914  0.10743  -0.25841 406 HOH A O   
4332 O  O   . HOH K .   ? 0.28346 0.26939 0.66382 0.05037  0.13787  0.10694  407 HOH A O   
4333 O  O   A HOH K .   ? 0.31631 0.41654 0.34125 0.06458  0.16320  -0.00243 408 HOH A O   
4334 O  O   . HOH K .   ? 0.39340 0.57209 0.38295 0.15313  -0.13398 -0.12700 409 HOH A O   
4335 O  O   . HOH K .   ? 0.23444 0.17885 0.41972 -0.02662 0.06762  0.02826  410 HOH A O   
4336 O  O   B HOH K .   ? 0.32114 0.20168 0.10415 0.02035  0.03529  0.04587  411 HOH A O   
4337 O  O   . HOH K .   ? 0.45050 0.48805 0.19938 0.27413  0.03544  0.04710  412 HOH A O   
4338 O  O   . HOH K .   ? 1.00868 0.45790 1.06950 0.25525  0.06693  -0.16213 413 HOH A O   
4339 O  O   . HOH K .   ? 0.49499 0.48824 0.57911 0.29328  0.02080  0.03489  414 HOH A O   
4340 O  O   A HOH K .   ? 0.31240 0.27394 0.12752 0.03638  -0.05032 -0.01408 415 HOH A O   
4341 O  O   . HOH K .   ? 0.16079 0.15458 0.12735 -0.01484 0.02125  -0.01775 416 HOH A O   
4342 O  O   B HOH K .   ? 0.17368 0.21424 0.16071 0.02996  -0.00611 -0.01690 417 HOH A O   
4343 O  O   . HOH K .   ? 0.36651 0.26292 0.13667 0.00759  -0.00405 0.04997  418 HOH A O   
4344 O  O   . HOH K .   ? 0.53913 0.53696 0.28291 -0.30997 -0.12440 0.12989  419 HOH A O   
4345 O  O   . HOH K .   ? 0.25510 0.42510 0.70353 0.01843  0.06639  0.29301  420 HOH A O   
4346 O  O   . HOH K .   ? 1.10991 0.31680 0.42437 0.06089  -0.30261 -0.01904 421 HOH A O   
4347 O  O   . HOH K .   ? 0.28031 0.70680 0.25668 0.19275  -0.00756 -0.07610 422 HOH A O   
4348 O  O   . HOH K .   ? 0.24484 0.36452 0.42360 -0.08193 0.09630  -0.07381 423 HOH A O   
4349 O  O   . HOH K .   ? 0.51958 0.70161 0.56038 -0.21524 -0.23114 -0.07064 424 HOH A O   
4350 O  O   . HOH K .   ? 0.16430 0.31866 0.13931 -0.03813 -0.01403 0.04476  425 HOH A O   
4351 O  O   . HOH K .   ? 0.31595 0.28949 0.37487 0.08688  0.09621  0.00906  426 HOH A O   
4352 O  O   . HOH K .   ? 0.64217 0.22854 0.32103 -0.00997 -0.23653 0.01835  427 HOH A O   
4353 O  O   . HOH K .   ? 0.57984 0.86682 0.33508 -0.23055 -0.13537 0.17145  428 HOH A O   
4354 O  O   . HOH K .   ? 0.43325 0.33656 0.45493 -0.09983 0.01908  -0.15239 429 HOH A O   
4355 O  O   . HOH K .   ? 0.14132 0.21172 0.22147 0.01143  0.04287  -0.05306 430 HOH A O   
4356 O  O   . HOH K .   ? 0.23908 0.53971 0.21966 0.03068  0.06566  0.04134  431 HOH A O   
4357 O  O   . HOH K .   ? 0.20408 0.27201 0.17175 0.07535  0.05260  0.00872  432 HOH A O   
4358 O  O   . HOH K .   ? 0.40478 0.25881 0.57257 0.02516  0.25999  0.05151  433 HOH A O   
4359 O  O   . HOH K .   ? 0.63682 0.45105 0.33839 0.01867  0.06632  0.14108  434 HOH A O   
4360 O  O   . HOH K .   ? 0.16079 0.21259 0.14746 -0.02963 0.02294  -0.00882 435 HOH A O   
4361 O  O   . HOH K .   ? 0.55454 0.61457 0.36484 -0.11896 0.04308  -0.23066 436 HOH A O   
4362 O  O   . HOH K .   ? 0.44800 0.78705 0.25818 -0.32629 0.03906  -0.06727 437 HOH A O   
4363 O  O   . HOH K .   ? 0.16558 0.18874 0.10808 -0.02168 0.02442  -0.01856 438 HOH A O   
4364 O  O   . HOH K .   ? 0.30343 0.35794 0.22463 -0.01382 -0.01694 0.00178  439 HOH A O   
4365 O  O   . HOH K .   ? 0.72302 0.44356 0.73660 0.14604  -0.41966 -0.09361 440 HOH A O   
4366 O  O   . HOH K .   ? 0.28112 0.35209 0.34322 -0.08008 -0.05740 -0.15696 441 HOH A O   
4367 O  O   . HOH K .   ? 0.45171 0.48495 0.73870 -0.05558 0.24009  0.01081  442 HOH A O   
4368 O  O   . HOH K .   ? 0.31955 0.35300 0.16019 0.16017  0.03889  0.07196  443 HOH A O   
4369 O  O   . HOH K .   ? 0.16910 0.19883 0.12028 -0.00784 0.03415  0.00469  444 HOH A O   
4370 O  O   . HOH K .   ? 0.34804 0.22452 0.20556 0.02257  0.06821  0.05622  445 HOH A O   
4371 O  O   . HOH K .   ? 0.40659 0.41657 0.73854 0.01439  0.10836  -0.17026 446 HOH A O   
4372 O  O   . HOH K .   ? 0.17942 0.16917 0.16990 -0.00574 0.03498  -0.00788 447 HOH A O   
4373 O  O   . HOH K .   ? 0.55497 0.58607 0.23461 -0.06440 -0.12793 0.10639  448 HOH A O   
4374 O  O   . HOH K .   ? 0.62106 0.68142 0.51599 -0.16605 0.08436  0.26411  449 HOH A O   
4375 O  O   . HOH K .   ? 0.21754 0.22969 0.20894 0.01915  -0.06487 -0.06728 450 HOH A O   
4376 O  O   . HOH K .   ? 0.14379 0.14181 0.10915 -0.01851 -0.00018 -0.02143 451 HOH A O   
4377 O  O   A HOH K .   ? 0.23692 0.35336 0.31898 -0.03609 0.09431  -0.12379 452 HOH A O   
4378 O  O   . HOH K .   ? 0.25378 0.60173 0.38487 0.01379  0.08193  -0.20083 453 HOH A O   
4379 O  O   . HOH K .   ? 0.26649 0.46159 0.47060 0.02840  0.02085  -0.15801 454 HOH A O   
4380 O  O   . HOH K .   ? 0.19590 0.27347 0.23652 0.00453  -0.05525 0.05661  455 HOH A O   
4381 O  O   . HOH K .   ? 0.31122 0.21361 0.36554 -0.05435 -0.02912 -0.07480 456 HOH A O   
4382 O  O   . HOH K .   ? 0.21467 0.20677 0.18896 0.01162  0.02699  0.01292  457 HOH A O   
4383 O  O   . HOH K .   ? 0.64477 0.33334 0.51678 0.04264  0.09205  -0.21217 458 HOH A O   
4384 O  O   . HOH K .   ? 0.47323 0.39970 0.62336 -0.16561 0.29454  -0.21161 459 HOH A O   
4385 O  O   . HOH K .   ? 0.20591 0.27059 0.28404 0.02758  0.04483  0.00574  460 HOH A O   
4386 O  O   . HOH K .   ? 0.25139 0.24096 0.20860 0.00714  -0.01978 -0.02956 461 HOH A O   
4387 O  O   . HOH K .   ? 0.34206 0.86564 0.22884 -0.00640 -0.03436 -0.03790 462 HOH A O   
4388 O  O   . HOH K .   ? 0.19166 0.24806 0.30337 -0.00138 0.03630  0.06879  463 HOH A O   
4389 O  O   . HOH K .   ? 0.26094 0.27084 0.20071 0.07573  -0.02455 0.01097  464 HOH A O   
4390 O  O   . HOH K .   ? 0.35943 0.30446 0.18937 -0.00921 0.03991  -0.03647 465 HOH A O   
4391 O  O   . HOH K .   ? 0.45259 0.40765 0.23081 0.18649  -0.13332 -0.08392 466 HOH A O   
4392 O  O   . HOH K .   ? 0.48681 0.25808 0.48522 -0.09516 -0.26997 0.11876  467 HOH A O   
4393 O  O   . HOH K .   ? 0.31588 0.29070 0.49710 -0.03342 0.07921  -0.05046 468 HOH A O   
4394 O  O   . HOH K .   ? 0.64021 0.75859 0.34619 -0.18466 0.00875  -0.22089 469 HOH A O   
4395 O  O   . HOH K .   ? 0.21295 0.52682 0.47520 -0.05087 -0.07397 -0.12279 470 HOH A O   
4396 O  O   . HOH K .   ? 0.27476 0.46480 0.12956 -0.10431 0.00483  0.01682  471 HOH A O   
4397 O  O   . HOH K .   ? 0.47211 0.26813 0.72475 -0.07354 -0.18352 -0.04301 472 HOH A O   
4398 O  O   . HOH K .   ? 0.33095 0.50711 0.26393 -0.15626 -0.05659 0.10388  473 HOH A O   
4399 O  O   . HOH K .   ? 0.68592 0.37535 0.58629 -0.22441 0.21072  -0.15915 474 HOH A O   
4400 O  O   . HOH K .   ? 0.18328 0.17920 0.08990 -0.03051 0.04177  -0.00775 475 HOH A O   
4401 O  O   . HOH K .   ? 0.24608 0.67335 0.44873 0.00064  0.00376  -0.31687 476 HOH A O   
4402 O  O   . HOH K .   ? 0.56862 0.71470 0.37612 0.20068  -0.09510 -0.08002 477 HOH A O   
4403 O  O   . HOH K .   ? 0.15544 0.18870 0.11684 0.00068  -0.01889 0.01781  478 HOH A O   
4404 O  O   . HOH K .   ? 0.47570 0.35307 0.54445 -0.17564 -0.26546 0.15976  479 HOH A O   
4405 O  O   . HOH K .   ? 0.21909 0.21833 0.21980 -0.00838 -0.01700 -0.00226 480 HOH A O   
4406 O  O   . HOH K .   ? 0.37181 0.22559 0.19099 -0.02599 0.01741  0.01019  481 HOH A O   
4407 O  O   . HOH K .   ? 0.28487 0.58597 0.19476 0.04745  0.01224  -0.00573 482 HOH A O   
4408 O  O   . HOH K .   ? 0.47541 0.38419 0.23016 -0.08950 0.14376  -0.06540 483 HOH A O   
4409 O  O   . HOH K .   ? 0.18344 0.26202 0.31387 0.00698  0.04689  0.00960  484 HOH A O   
4410 O  O   . HOH K .   ? 0.50555 0.57024 0.30198 0.17142  0.17330  0.01691  485 HOH A O   
4411 O  O   . HOH K .   ? 0.33741 0.31132 0.20826 -0.15673 -0.09768 0.05918  486 HOH A O   
4412 O  O   . HOH K .   ? 0.52424 0.57250 0.34051 -0.27844 -0.15582 0.07851  487 HOH A O   
4413 O  O   . HOH K .   ? 0.52020 0.53417 0.63901 0.08711  -0.31007 0.02098  488 HOH A O   
4414 O  O   . HOH K .   ? 0.19304 0.27921 0.22991 -0.01081 -0.03748 -0.07384 489 HOH A O   
4415 O  O   . HOH K .   ? 0.47885 0.32535 0.61888 0.02448  0.28355  0.03318  490 HOH A O   
4416 O  O   . HOH K .   ? 0.46442 0.67604 0.29108 -0.11848 -0.15517 0.11176  491 HOH A O   
4417 O  O   . HOH K .   ? 0.34684 0.70460 0.54337 0.10913  -0.03592 -0.16814 492 HOH A O   
4418 O  O   . HOH K .   ? 0.23967 0.55880 0.32810 -0.08892 0.06041  -0.04410 493 HOH A O   
4419 O  O   . HOH K .   ? 0.22326 0.31565 0.13044 0.04968  0.05421  0.00651  494 HOH A O   
4420 O  O   . HOH K .   ? 0.14556 0.18041 0.10924 -0.00693 0.00387  -0.01145 495 HOH A O   
4421 O  O   . HOH K .   ? 0.51074 0.32822 0.42677 0.21020  0.14208  0.03503  496 HOH A O   
4422 O  O   . HOH K .   ? 0.83672 0.29335 0.33331 0.19529  0.08205  0.00955  497 HOH A O   
4423 O  O   . HOH K .   ? 0.79545 0.45015 0.53733 -0.22189 0.25148  -0.01052 498 HOH A O   
4424 O  O   . HOH K .   ? 1.03243 0.54210 0.42266 0.08823  -0.21109 -0.11236 499 HOH A O   
4425 O  O   . HOH K .   ? 0.56452 0.52575 0.30318 -0.05329 0.09525  -0.16168 500 HOH A O   
4426 O  O   . HOH K .   ? 0.24661 0.43412 0.44724 0.11029  -0.01656 -0.17160 501 HOH A O   
4427 O  O   A HOH K .   ? 0.33813 0.30491 0.15235 -0.05945 0.04570  0.08486  502 HOH A O   
4428 O  O   B HOH K .   ? 0.24986 0.16519 0.33260 -0.02213 -0.11501 -0.05424 502 HOH A O   
4429 O  O   . HOH K .   ? 0.18795 0.22791 0.12853 -0.04331 -0.01108 0.01102  503 HOH A O   
4430 O  O   A HOH K .   ? 0.20756 0.23290 0.27285 0.01442  -0.06404 -0.00137 504 HOH A O   
4431 O  O   B HOH K .   ? 0.20233 0.41491 0.32873 -0.00342 -0.13783 -0.03906 504 HOH A O   
4432 O  O   . HOH K .   ? 0.14711 0.18000 0.14887 -0.01069 0.01961  -0.01313 505 HOH A O   
4433 O  O   . HOH K .   ? 0.34105 0.26261 0.17749 0.05674  -0.07894 -0.03162 506 HOH A O   
4434 O  O   . HOH K .   ? 0.25967 0.25992 0.17997 -0.08959 -0.05428 -0.00234 507 HOH A O   
4435 O  O   . HOH K .   ? 0.44014 0.49154 0.45240 -0.03525 0.05649  -0.14009 508 HOH A O   
4436 O  O   . HOH K .   ? 0.21770 0.48528 0.59690 0.02489  -0.02649 -0.31248 509 HOH A O   
4437 O  O   . HOH K .   ? 0.24768 0.32205 0.74767 0.01428  -0.02619 -0.09240 510 HOH A O   
4438 O  O   . HOH K .   ? 0.22457 0.36182 0.35069 -0.05212 -0.08254 0.06511  511 HOH A O   
4439 O  O   A HOH K .   ? 0.40767 0.25670 0.30877 -0.09079 0.02938  0.11046  512 HOH A O   
4440 O  O   B HOH K .   ? 0.19391 0.18599 0.25735 -0.03667 0.07386  0.01844  512 HOH A O   
4441 O  O   . HOH K .   ? 0.26144 0.38697 0.75485 -0.04311 0.16965  -0.09115 513 HOH A O   
4442 O  O   . HOH K .   ? 0.23510 0.23149 0.13997 -0.06921 0.04090  -0.03781 514 HOH A O   
4443 O  O   . HOH K .   ? 0.27775 0.41016 0.17048 -0.02650 0.04802  -0.03341 515 HOH A O   
4444 O  O   . HOH K .   ? 0.18618 0.24680 0.16130 -0.04428 0.02522  -0.01156 516 HOH A O   
4445 O  O   . HOH K .   ? 0.23947 0.31979 0.24839 -0.02086 -0.02092 0.10627  517 HOH A O   
4446 O  O   . HOH K .   ? 0.28855 0.34483 0.20980 -0.03036 -0.01507 -0.00909 518 HOH A O   
4447 O  O   . HOH K .   ? 0.30100 0.21678 0.65671 0.02545  0.14035  -0.07369 519 HOH A O   
4448 O  O   A HOH K .   ? 0.13727 0.19820 0.26399 0.00904  0.00311  0.10377  520 HOH A O   
4449 O  O   B HOH K .   ? 0.31366 0.36042 0.12645 -0.06531 -0.05568 -0.03215 520 HOH A O   
4450 O  O   . HOH K .   ? 0.30392 0.40424 0.28478 -0.06337 0.02429  -0.02619 521 HOH A O   
4451 O  O   A HOH K .   ? 0.43055 0.39774 0.46502 -0.01127 -0.05585 -0.05399 522 HOH A O   
4452 O  O   B HOH K .   ? 0.46662 0.40633 0.30738 -0.09826 -0.19552 -0.01744 522 HOH A O   
4453 O  O   . HOH K .   ? 0.46512 0.79519 0.55197 0.13744  0.01361  -0.11323 523 HOH A O   
4454 O  O   . HOH K .   ? 0.23329 0.38923 0.78435 -0.00037 0.10536  0.12589  524 HOH A O   
4455 O  O   . HOH K .   ? 0.76202 0.50375 0.29739 0.32885  0.10635  0.09715  525 HOH A O   
4456 O  O   . HOH K .   ? 0.76133 0.34425 0.98731 0.04151  0.13279  0.18837  526 HOH A O   
4457 O  O   . HOH K .   ? 0.65142 0.55289 0.49549 0.21440  0.25761  0.13147  527 HOH A O   
4458 O  O   . HOH K .   ? 0.16206 0.29445 0.57230 -0.01530 0.02045  -0.04918 528 HOH A O   
4459 O  O   . HOH K .   ? 0.50641 0.39853 0.30690 0.16144  0.18447  0.02702  529 HOH A O   
4460 O  O   . HOH K .   ? 0.59606 0.89476 0.36348 -0.12374 0.05489  0.22062  530 HOH A O   
4461 O  O   . HOH K .   ? 0.60415 0.59406 0.55709 -0.00118 0.11173  -0.16537 531 HOH A O   
4462 O  O   . HOH K .   ? 0.33357 0.50295 0.60199 -0.07480 0.18660  0.03209  532 HOH A O   
4463 O  O   . HOH K .   ? 0.83809 0.96191 0.34744 0.26696  0.11635  0.06764  533 HOH A O   
4464 O  O   . HOH K .   ? 0.66300 0.47678 0.79338 -0.25894 -0.19401 -0.07138 534 HOH A O   
4465 O  O   . HOH K .   ? 0.40887 0.46898 0.70944 0.02248  -0.21817 -0.22875 535 HOH A O   
4466 O  O   . HOH K .   ? 0.77103 0.67116 0.30517 0.09731  0.12236  0.07501  536 HOH A O   
4467 O  O   . HOH K .   ? 0.33518 0.50501 0.45333 0.05131  0.14706  0.23577  537 HOH A O   
4468 O  O   . HOH K .   ? 0.39425 0.35395 0.39126 -0.02304 0.11638  0.05622  538 HOH A O   
4469 O  O   . HOH K .   ? 0.33027 0.75781 0.33942 -0.11186 0.11737  -0.11916 539 HOH A O   
4470 O  O   . HOH K .   ? 0.24167 0.22098 0.28659 -0.03254 -0.01936 0.04843  540 HOH A O   
4471 O  O   . HOH K .   ? 0.83456 0.34627 0.26130 -0.22813 0.06147  -0.04736 541 HOH A O   
4472 O  O   . HOH K .   ? 0.27841 0.25748 0.23104 -0.03027 0.04494  0.00979  542 HOH A O   
4473 O  O   . HOH K .   ? 0.80783 0.32794 0.56984 0.17067  -0.23454 0.01201  543 HOH A O   
4474 O  O   . HOH K .   ? 0.36011 0.41790 0.28876 -0.02244 0.05891  0.03782  544 HOH A O   
4475 O  O   . HOH K .   ? 0.69289 0.76728 0.71479 -0.15488 -0.13570 -0.26565 545 HOH A O   
4476 O  O   . HOH K .   ? 0.19716 0.31207 0.23700 0.06204  0.02227  -0.00452 546 HOH A O   
4477 O  O   . HOH K .   ? 0.36310 0.46273 0.89829 -0.02898 0.20803  -0.24687 547 HOH A O   
4478 O  O   . HOH K .   ? 0.27972 0.68154 0.18444 -0.08488 -0.02736 -0.01173 548 HOH A O   
4479 O  O   . HOH K .   ? 0.49264 0.47384 0.49302 -0.05903 0.27297  -0.13989 549 HOH A O   
4480 O  O   . HOH K .   ? 0.33161 0.50893 1.16545 0.01718  0.11834  -0.17228 550 HOH A O   
4481 O  O   . HOH K .   ? 0.44543 0.37270 0.80396 -0.13802 0.09343  0.02016  551 HOH A O   
4482 O  O   . HOH K .   ? 0.46123 0.45929 0.48421 -0.15027 0.15890  -0.16319 552 HOH A O   
4483 O  O   . HOH K .   ? 0.22236 0.50411 0.46701 -0.03217 0.04646  0.19625  553 HOH A O   
4484 O  O   . HOH K .   ? 0.24444 0.42069 0.49369 0.06788  -0.07477 -0.01191 554 HOH A O   
4485 O  O   . HOH K .   ? 0.40770 0.51083 0.86815 0.17161  -0.20062 -0.28368 555 HOH A O   
4486 O  O   . HOH K .   ? 0.43318 0.39119 0.53931 0.14664  0.25564  0.09261  556 HOH A O   
4487 O  O   . HOH K .   ? 0.57708 0.44114 0.87376 0.09805  -0.12298 0.26343  557 HOH A O   
4488 O  O   . HOH K .   ? 0.78071 0.46437 0.71827 -0.22566 0.42243  -0.18654 558 HOH A O   
4489 O  O   . HOH K .   ? 0.46233 0.58007 0.76217 0.23572  0.13472  0.27357  559 HOH A O   
4490 O  O   . HOH K .   ? 0.55391 0.49741 0.55459 0.22522  0.12814  0.24660  560 HOH A O   
4491 O  O   . HOH K .   ? 0.44040 0.48619 0.47513 0.03404  0.16981  0.16600  561 HOH A O   
4492 O  O   . HOH K .   ? 0.38541 0.35407 0.24734 0.08833  -0.14002 -0.05131 562 HOH A O   
4493 O  O   . HOH K .   ? 0.31551 0.74201 0.80288 -0.13224 0.00090  -0.08672 563 HOH A O   
4494 O  O   . HOH K .   ? 0.54561 0.42541 0.24991 0.20173  0.13610  0.10991  564 HOH A O   
4495 O  O   . HOH K .   ? 0.24630 0.43828 0.24207 -0.11455 -0.03233 -0.08470 565 HOH A O   
4496 O  O   . HOH K .   ? 0.35748 0.41182 0.32194 0.09037  -0.10571 0.04848  566 HOH A O   
4497 O  O   . HOH K .   ? 0.39798 0.60447 1.10437 0.11897  0.16023  -0.01372 567 HOH A O   
4498 O  O   . HOH K .   ? 0.23737 0.29270 0.24059 -0.01913 -0.00468 0.04241  568 HOH A O   
4499 O  O   . HOH K .   ? 0.59657 0.40741 0.58843 -0.00859 0.15737  -0.06478 569 HOH A O   
4500 O  O   . HOH K .   ? 0.46010 0.68809 0.76942 0.13057  -0.03775 0.15758  570 HOH A O   
4501 O  O   . HOH K .   ? 0.42355 0.54818 0.45908 -0.09923 0.17267  -0.18119 571 HOH A O   
4502 O  O   . HOH K .   ? 0.42575 0.73467 1.11959 -0.11894 0.07939  0.33693  572 HOH A O   
4503 O  O   A HOH K .   ? 0.64643 0.36502 0.25795 -0.06840 -0.12622 0.04101  573 HOH A O   
4504 O  O   . HOH K .   ? 0.35622 0.58472 0.79691 0.09547  0.14154  0.00732  574 HOH A O   
4505 O  O   . HOH K .   ? 0.85148 0.41770 0.49444 0.08273  -0.14766 -0.11970 575 HOH A O   
4506 O  O   . HOH K .   ? 0.61622 0.42809 0.85816 0.18803  -0.07570 0.20847  576 HOH A O   
4507 O  O   . HOH K .   ? 0.52643 0.81139 0.28195 -0.15200 0.09920  -0.14524 577 HOH A O   
4508 O  O   . HOH K .   ? 0.42502 0.39843 0.26410 -0.16850 0.02870  0.01111  578 HOH A O   
4509 O  O   . HOH K .   ? 0.29693 0.44651 0.91225 -0.06062 -0.06304 0.04423  579 HOH A O   
4510 O  O   . HOH K .   ? 0.52380 0.54212 0.21248 0.20301  0.03228  0.09049  580 HOH A O   
4511 O  O   . HOH K .   ? 0.41326 0.46199 0.59646 -0.11889 0.09455  -0.27394 581 HOH A O   
4512 O  O   . HOH K .   ? 0.52885 0.76956 0.46011 0.11220  -0.09554 0.04047  582 HOH A O   
4513 O  O   . HOH K .   ? 0.90116 0.73285 0.56054 -0.13032 0.31374  0.17377  583 HOH A O   
4514 O  O   . HOH K .   ? 0.40512 0.21688 0.50118 -0.09232 0.02156  0.08054  584 HOH A O   
4515 O  O   . HOH K .   ? 0.45302 0.46834 0.80419 -0.20003 -0.12754 -0.10902 585 HOH A O   
4516 O  O   . HOH K .   ? 0.29801 0.54659 0.55139 0.03517  -0.10599 -0.26249 586 HOH A O   
4517 O  O   . HOH K .   ? 0.28062 0.27484 0.32610 -0.03956 -0.00387 0.00823  587 HOH A O   
4518 O  O   . HOH K .   ? 0.48786 0.55806 0.84469 -0.13227 0.02095  -0.11537 588 HOH A O   
4519 O  O   . HOH K .   ? 0.69900 0.55457 0.40776 0.10634  -0.10204 -0.08339 589 HOH A O   
4520 O  O   . HOH K .   ? 0.52492 0.69457 0.64916 -0.06189 0.17523  -0.06127 590 HOH A O   
4521 O  O   . HOH K .   ? 0.51084 0.80591 0.40531 0.06111  -0.06192 -0.29710 591 HOH A O   
4522 O  O   . HOH K .   ? 0.58042 0.48408 0.55646 -0.28401 0.18108  -0.06790 592 HOH A O   
4523 O  O   . HOH K .   ? 0.41582 0.70939 0.70651 -0.19564 0.17109  -0.40078 593 HOH A O   
4524 O  O   . HOH K .   ? 0.58337 0.92250 0.36672 0.13764  0.15138  0.05399  594 HOH A O   
4525 O  O   . HOH K .   ? 0.39678 0.75696 1.05819 -0.07656 -0.08889 0.02253  595 HOH A O   
4526 O  O   . HOH K .   ? 0.80280 0.49013 0.76505 0.12345  0.25345  0.28971  596 HOH A O   
4527 O  O   . HOH K .   ? 0.51465 0.72058 0.71682 0.10825  0.00158  -0.05219 597 HOH A O   
4528 O  O   . HOH K .   ? 0.30372 0.76467 0.79564 -0.15765 0.02760  -0.04316 598 HOH A O   
4529 O  O   . HOH K .   ? 0.66551 0.53448 0.50831 -0.10552 -0.10356 0.29442  599 HOH A O   
4530 O  O   . HOH K .   ? 0.49846 0.63927 0.61726 0.04751  0.13672  0.12031  600 HOH A O   
4531 O  O   . HOH K .   ? 0.94302 0.53919 0.86703 0.16519  -0.08948 0.02943  601 HOH A O   
4532 O  O   . HOH K .   ? 0.33326 0.60316 0.60363 0.07789  -0.00014 0.30183  602 HOH A O   
4533 O  O   . HOH K .   ? 0.70461 0.85749 0.34463 0.11128  0.04384  0.13478  603 HOH A O   
4534 O  O   A HOH K .   ? 0.41812 0.31760 0.19581 -0.12758 -0.07167 0.10382  604 HOH A O   
4535 O  O   B HOH K .   ? 0.36053 0.18139 0.50147 -0.06543 -0.18096 0.05270  604 HOH A O   
4536 O  O   . HOH K .   ? 0.54932 0.31323 1.09233 -0.04316 0.20689  0.06258  605 HOH A O   
4537 O  O   . HOH K .   ? 0.39447 0.47566 1.05915 -0.14936 -0.11836 0.13613  606 HOH A O   
4538 O  O   . HOH K .   ? 0.82812 0.78538 0.41273 0.34948  0.03120  0.01963  607 HOH A O   
4539 O  O   . HOH K .   ? 0.69097 0.82313 0.44991 -0.41868 0.17056  -0.15205 608 HOH A O   
4540 O  O   . HOH K .   ? 0.53203 0.46557 0.94746 0.05977  0.04623  0.24543  609 HOH A O   
4541 O  O   . HOH K .   ? 0.75338 0.59796 0.67089 0.29478  0.08061  0.07979  610 HOH A O   
4542 O  O   . HOH K .   ? 0.44806 0.43762 0.71992 -0.03131 -0.07739 0.07854  611 HOH A O   
4543 O  O   . HOH K .   ? 0.59646 0.63531 0.67735 -0.31138 0.18561  -0.27946 612 HOH A O   
4544 O  O   . HOH K .   ? 0.60223 0.70615 0.52811 0.12011  0.16363  0.14538  613 HOH A O   
4545 O  O   . HOH K .   ? 0.91710 0.72663 0.60015 0.41385  0.32982  0.28947  614 HOH A O   
4546 O  O   . HOH K .   ? 0.33031 0.56025 0.22909 -0.11888 -0.01743 -0.04257 615 HOH A O   
4547 O  O   . HOH K .   ? 0.28238 0.42331 0.88932 -0.08947 0.04569  -0.16400 616 HOH A O   
4548 O  O   . HOH K .   ? 0.32596 0.28281 0.43836 -0.06140 0.08378  -0.04291 617 HOH A O   
4549 O  O   . HOH K .   ? 0.42721 0.59440 0.66480 0.05635  -0.18028 0.05680  618 HOH A O   
4550 O  O   . HOH K .   ? 0.71060 0.38330 0.39261 0.02051  -0.28450 0.02521  619 HOH A O   
4551 O  O   . HOH K .   ? 0.55033 1.24873 0.50946 0.23166  -0.04370 -0.21641 620 HOH A O   
4552 O  O   . HOH K .   ? 0.49067 0.98408 0.46256 -0.10286 -0.03584 0.02268  621 HOH A O   
4553 O  O   . HOH K .   ? 0.32787 0.61733 0.41437 -0.15068 0.00292  0.22464  622 HOH A O   
4554 O  O   . HOH K .   ? 0.71148 0.43255 0.21428 0.21607  -0.04428 -0.00097 623 HOH A O   
4555 O  O   . HOH K .   ? 0.46602 0.54057 0.55385 0.23812  0.23980  0.28747  624 HOH A O   
4556 O  O   . HOH K .   ? 0.29854 0.46291 0.57183 0.01366  0.09202  -0.14173 625 HOH A O   
4557 O  O   . HOH K .   ? 0.61648 0.80301 0.56510 0.25805  0.21164  0.26126  626 HOH A O   
4558 O  O   . HOH K .   ? 0.49783 0.35514 1.11391 0.04157  -0.04600 -0.13193 627 HOH A O   
4559 O  O   . HOH K .   ? 0.30720 0.63668 0.28397 -0.18477 -0.07580 0.10382  628 HOH A O   
4560 O  O   . HOH K .   ? 0.29003 0.55066 0.68667 0.00948  0.13078  0.11724  629 HOH A O   
4561 O  O   . HOH K .   ? 0.24426 0.48291 0.24618 -0.05427 0.08323  -0.05297 630 HOH A O   
4562 O  O   . HOH K .   ? 0.31477 1.08374 0.78308 -0.01346 0.04757  -0.11845 631 HOH A O   
4563 O  O   . HOH K .   ? 0.31860 0.28759 0.22503 0.02942  -0.03632 -0.02892 632 HOH A O   
4564 O  O   . HOH K .   ? 0.40234 0.66887 0.52728 0.02106  -0.06815 0.14169  633 HOH A O   
4565 O  O   . HOH K .   ? 0.64497 0.19665 0.63488 0.05027  -0.09069 0.00410  634 HOH A O   
4566 O  O   . HOH K .   ? 0.57951 0.46549 0.49725 -0.05636 0.26926  -0.01686 635 HOH A O   
4567 O  O   . HOH K .   ? 0.62815 0.36672 0.59900 0.16297  -0.18687 -0.10912 636 HOH A O   
4568 O  O   . HOH K .   ? 0.27536 0.21183 0.24299 -0.03215 0.06823  0.03245  637 HOH A O   
4569 O  O   . HOH K .   ? 0.38264 0.46268 0.62404 0.04870  -0.03562 -0.07044 638 HOH A O   
4570 O  O   . HOH K .   ? 0.39971 0.84966 0.58489 0.21422  -0.06958 -0.33523 639 HOH A O   
4571 O  O   . HOH K .   ? 0.74964 0.35972 0.53756 -0.16924 0.32109  -0.05263 640 HOH A O   
4572 O  O   . HOH K .   ? 0.28399 0.31826 0.27053 -0.01548 0.04415  -0.03057 641 HOH A O   
4573 O  O   . HOH K .   ? 0.38485 0.53193 0.30839 0.25840  -0.02330 0.02181  642 HOH A O   
4574 O  O   . HOH K .   ? 0.36607 0.77887 0.67947 0.02429  -0.04398 0.09315  643 HOH A O   
4575 O  O   . HOH K .   ? 0.35866 0.63490 0.44145 0.12734  0.19114  -0.02978 644 HOH A O   
4576 O  O   . HOH K .   ? 0.49877 0.68562 0.69077 0.24719  0.02141  0.28723  645 HOH A O   
4577 O  O   . HOH K .   ? 0.34285 0.54647 0.79326 -0.05663 -0.05338 -0.03797 646 HOH A O   
4578 O  O   . HOH K .   ? 0.58310 0.44863 0.25156 0.00040  0.15642  0.09333  647 HOH A O   
4579 O  O   . HOH K .   ? 0.21944 0.29312 0.28897 0.03348  0.03826  -0.04331 648 HOH A O   
4580 O  O   . HOH K .   ? 0.76458 0.77185 0.55971 0.38530  0.15084  0.27886  649 HOH A O   
4581 O  O   . HOH K .   ? 0.63892 0.36967 0.46828 -0.26776 -0.06205 0.02565  650 HOH A O   
4582 O  O   . HOH K .   ? 0.38582 0.64260 0.91754 -0.03934 0.20460  -0.09643 651 HOH A O   
4583 O  O   . HOH K .   ? 0.35261 0.52606 0.26153 0.19003  0.04442  0.03615  652 HOH A O   
4584 O  O   . HOH K .   ? 0.39096 0.57263 0.18165 0.17935  -0.04094 -0.05101 653 HOH A O   
4585 O  O   . HOH K .   ? 0.18694 0.44294 0.23395 0.07066  0.02752  0.10116  654 HOH A O   
4586 O  O   . HOH K .   ? 0.83023 0.48050 0.29914 0.20197  -0.14979 -0.04622 655 HOH A O   
4587 O  O   . HOH K .   ? 0.44649 0.53967 0.24143 -0.05509 -0.06314 -0.07996 656 HOH A O   
4588 O  O   A HOH K .   ? 0.46190 0.30891 0.43882 -0.07085 -0.11587 0.06563  657 HOH A O   
4589 O  O   B HOH K .   ? 0.42667 0.60193 0.48296 -0.10081 -0.02504 0.23504  657 HOH A O   
4590 O  O   . HOH K .   ? 0.50608 0.62591 0.74165 0.11714  0.12663  -0.05904 658 HOH A O   
4591 O  O   . HOH K .   ? 0.44167 0.97014 0.41621 -0.20934 -0.02779 0.21538  659 HOH A O   
4592 O  O   . HOH K .   ? 0.21280 0.40622 0.10884 -0.03022 0.01476  0.02842  660 HOH A O   
4593 O  O   . HOH K .   ? 0.55479 0.78821 0.74504 0.08029  0.27967  -0.13682 661 HOH A O   
4594 O  O   . HOH K .   ? 0.35970 0.41070 0.91669 0.03982  -0.08056 -0.08095 662 HOH A O   
4595 O  O   . HOH K .   ? 0.75549 1.16091 0.33946 -0.12152 -0.03490 0.16641  663 HOH A O   
4596 O  O   . HOH K .   ? 0.38712 0.56910 0.50503 -0.04369 0.08677  -0.04869 664 HOH A O   
4597 O  O   . HOH K .   ? 0.35596 0.53803 0.34685 0.00624  0.08024  0.18814  665 HOH A O   
# 
