data_8R2Y
# 
_entry.id   8R2Y 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8R2Y         pdb_00008r2y 10.2210/pdb8r2y/pdb 
WWPDB D_1292134488 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-20 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8R2Y 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              jim.spencer@bristol.ac.uk 
_pdbx_contact_author.name_first         James 
_pdbx_contact_author.name_last          Spencer 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8611-4743 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Tooke, C.L.'    1 ? 
'Hinchliffe, P.' 2 ? 
'Spencer, J.'    3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of CTX-M-15 complexed with benzoxaborole AK-29' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Tooke, C.L.'    1 ? 
primary 'Hinchliffe, P.' 2 ? 
primary 'Spencer, J.'    3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Beta-lactamase              28292.990 1   3.5.2.6 ? ? ? 
2 non-polymer syn '2,1-benzoxaborol-1(3H)-ol' 133.940   1   ?       ? ? ? 
3 non-polymer syn 'DIMETHYL SULFOXIDE'        78.133    2   ?       ? ? ? 
4 non-polymer syn GLYCEROL                    92.094    1   ?       ? ? ? 
5 non-polymer syn 'SULFATE ION'               96.063    6   ?       ? ? ? 
6 non-polymer syn 'CHLORIDE ION'              35.453    1   ?       ? ? ? 
7 non-polymer syn 'SODIUM ION'                22.990    3   ?       ? ? ? 
8 water       nat water                       18.015    332 ?       ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GPQTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLV
NYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSP
RAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYF
TQPQPKAESRRDVLASAAKIVTDGL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GPQTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLV
NYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSP
RAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYF
TQPQPKAESRRDVLASAAKIVTDGL
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '2,1-benzoxaborol-1(3H)-ol' 6M9 
3 'DIMETHYL SULFOXIDE'        DMS 
4 GLYCEROL                    GOL 
5 'SULFATE ION'               SO4 
6 'CHLORIDE ION'              CL  
7 'SODIUM ION'                NA  
8 water                       HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLN n 
1 4   THR n 
1 5   ALA n 
1 6   ASP n 
1 7   VAL n 
1 8   GLN n 
1 9   GLN n 
1 10  LYS n 
1 11  LEU n 
1 12  ALA n 
1 13  GLU n 
1 14  LEU n 
1 15  GLU n 
1 16  ARG n 
1 17  GLN n 
1 18  SER n 
1 19  GLY n 
1 20  GLY n 
1 21  ARG n 
1 22  LEU n 
1 23  GLY n 
1 24  VAL n 
1 25  ALA n 
1 26  LEU n 
1 27  ILE n 
1 28  ASN n 
1 29  THR n 
1 30  ALA n 
1 31  ASP n 
1 32  ASN n 
1 33  SER n 
1 34  GLN n 
1 35  ILE n 
1 36  LEU n 
1 37  TYR n 
1 38  ARG n 
1 39  ALA n 
1 40  ASP n 
1 41  GLU n 
1 42  ARG n 
1 43  PHE n 
1 44  ALA n 
1 45  MET n 
1 46  CYS n 
1 47  SER n 
1 48  THR n 
1 49  SER n 
1 50  LYS n 
1 51  VAL n 
1 52  MET n 
1 53  ALA n 
1 54  ALA n 
1 55  ALA n 
1 56  ALA n 
1 57  VAL n 
1 58  LEU n 
1 59  LYS n 
1 60  LYS n 
1 61  SER n 
1 62  GLU n 
1 63  SER n 
1 64  GLU n 
1 65  PRO n 
1 66  ASN n 
1 67  LEU n 
1 68  LEU n 
1 69  ASN n 
1 70  GLN n 
1 71  ARG n 
1 72  VAL n 
1 73  GLU n 
1 74  ILE n 
1 75  LYS n 
1 76  LYS n 
1 77  SER n 
1 78  ASP n 
1 79  LEU n 
1 80  VAL n 
1 81  ASN n 
1 82  TYR n 
1 83  ASN n 
1 84  PRO n 
1 85  ILE n 
1 86  ALA n 
1 87  GLU n 
1 88  LYS n 
1 89  HIS n 
1 90  VAL n 
1 91  ASN n 
1 92  GLY n 
1 93  THR n 
1 94  MET n 
1 95  SER n 
1 96  LEU n 
1 97  ALA n 
1 98  GLU n 
1 99  LEU n 
1 100 SER n 
1 101 ALA n 
1 102 ALA n 
1 103 ALA n 
1 104 LEU n 
1 105 GLN n 
1 106 TYR n 
1 107 SER n 
1 108 ASP n 
1 109 ASN n 
1 110 VAL n 
1 111 ALA n 
1 112 MET n 
1 113 ASN n 
1 114 LYS n 
1 115 LEU n 
1 116 ILE n 
1 117 ALA n 
1 118 HIS n 
1 119 VAL n 
1 120 GLY n 
1 121 GLY n 
1 122 PRO n 
1 123 ALA n 
1 124 SER n 
1 125 VAL n 
1 126 THR n 
1 127 ALA n 
1 128 PHE n 
1 129 ALA n 
1 130 ARG n 
1 131 GLN n 
1 132 LEU n 
1 133 GLY n 
1 134 ASP n 
1 135 GLU n 
1 136 THR n 
1 137 PHE n 
1 138 ARG n 
1 139 LEU n 
1 140 ASP n 
1 141 ARG n 
1 142 THR n 
1 143 GLU n 
1 144 PRO n 
1 145 THR n 
1 146 LEU n 
1 147 ASN n 
1 148 THR n 
1 149 ALA n 
1 150 ILE n 
1 151 PRO n 
1 152 GLY n 
1 153 ASP n 
1 154 PRO n 
1 155 ARG n 
1 156 ASP n 
1 157 THR n 
1 158 THR n 
1 159 SER n 
1 160 PRO n 
1 161 ARG n 
1 162 ALA n 
1 163 MET n 
1 164 ALA n 
1 165 GLN n 
1 166 THR n 
1 167 LEU n 
1 168 ARG n 
1 169 ASN n 
1 170 LEU n 
1 171 THR n 
1 172 LEU n 
1 173 GLY n 
1 174 LYS n 
1 175 ALA n 
1 176 LEU n 
1 177 GLY n 
1 178 ASP n 
1 179 SER n 
1 180 GLN n 
1 181 ARG n 
1 182 ALA n 
1 183 GLN n 
1 184 LEU n 
1 185 VAL n 
1 186 THR n 
1 187 TRP n 
1 188 MET n 
1 189 LYS n 
1 190 GLY n 
1 191 ASN n 
1 192 THR n 
1 193 THR n 
1 194 GLY n 
1 195 ALA n 
1 196 ALA n 
1 197 SER n 
1 198 ILE n 
1 199 GLN n 
1 200 ALA n 
1 201 GLY n 
1 202 LEU n 
1 203 PRO n 
1 204 ALA n 
1 205 SER n 
1 206 TRP n 
1 207 VAL n 
1 208 VAL n 
1 209 GLY n 
1 210 ASP n 
1 211 LYS n 
1 212 THR n 
1 213 GLY n 
1 214 SER n 
1 215 GLY n 
1 216 GLY n 
1 217 TYR n 
1 218 GLY n 
1 219 THR n 
1 220 THR n 
1 221 ASN n 
1 222 ASP n 
1 223 ILE n 
1 224 ALA n 
1 225 VAL n 
1 226 ILE n 
1 227 TRP n 
1 228 PRO n 
1 229 LYS n 
1 230 ASP n 
1 231 ARG n 
1 232 ALA n 
1 233 PRO n 
1 234 LEU n 
1 235 ILE n 
1 236 LEU n 
1 237 VAL n 
1 238 THR n 
1 239 TYR n 
1 240 PHE n 
1 241 THR n 
1 242 GLN n 
1 243 PRO n 
1 244 GLN n 
1 245 PRO n 
1 246 LYS n 
1 247 ALA n 
1 248 GLU n 
1 249 SER n 
1 250 ARG n 
1 251 ARG n 
1 252 ASP n 
1 253 VAL n 
1 254 LEU n 
1 255 ALA n 
1 256 SER n 
1 257 ALA n 
1 258 ALA n 
1 259 LYS n 
1 260 ILE n 
1 261 VAL n 
1 262 THR n 
1 263 ASP n 
1 264 GLY n 
1 265 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   265 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 blaCTX-M-15 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Klebsiella pneumoniae' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     573 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              Solu 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
6M9 non-polymer         . '2,1-benzoxaborol-1(3H)-ol' ?                               'C7 H7 B O2'     133.940 
ALA 'L-peptide linking' y ALANINE                     ?                               'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                    ?                               'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                  ?                               'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'             ?                               'C4 H7 N O4'     133.103 
CL  non-polymer         . 'CHLORIDE ION'              ?                               'Cl -1'          35.453  
CYS 'L-peptide linking' y CYSTEINE                    ?                               'C3 H7 N O2 S'   121.158 
DMS non-polymer         . 'DIMETHYL SULFOXIDE'        ?                               'C2 H6 O S'      78.133  
GLN 'L-peptide linking' y GLUTAMINE                   ?                               'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'             ?                               'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                     ?                               'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL                    'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE                   ?                               'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                       ?                               'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                  ?                               'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                     ?                               'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                      ?                               'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                  ?                               'C5 H11 N O2 S'  149.211 
NA  non-polymer         . 'SODIUM ION'                ?                               'Na 1'           22.990  
PHE 'L-peptide linking' y PHENYLALANINE               ?                               'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                     ?                               'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                      ?                               'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'               ?                               'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE                   ?                               'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                  ?                               'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                    ?                               'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                      ?                               'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   24  ?   ?   ?   A . n 
A 1 2   PRO 2   25  ?   ?   ?   A . n 
A 1 3   GLN 3   26  ?   ?   ?   A . n 
A 1 4   THR 4   27  ?   ?   ?   A . n 
A 1 5   ALA 5   28  28  ALA ALA A . n 
A 1 6   ASP 6   29  29  ASP ASP A . n 
A 1 7   VAL 7   30  30  VAL VAL A . n 
A 1 8   GLN 8   31  31  GLN GLN A . n 
A 1 9   GLN 9   32  32  GLN GLN A . n 
A 1 10  LYS 10  33  33  LYS LYS A . n 
A 1 11  LEU 11  34  34  LEU LEU A . n 
A 1 12  ALA 12  35  35  ALA ALA A . n 
A 1 13  GLU 13  36  36  GLU GLU A . n 
A 1 14  LEU 14  37  37  LEU LEU A . n 
A 1 15  GLU 15  38  38  GLU GLU A . n 
A 1 16  ARG 16  39  39  ARG ARG A . n 
A 1 17  GLN 17  40  40  GLN GLN A . n 
A 1 18  SER 18  41  41  SER SER A . n 
A 1 19  GLY 19  42  42  GLY GLY A . n 
A 1 20  GLY 20  43  43  GLY GLY A . n 
A 1 21  ARG 21  44  44  ARG ARG A . n 
A 1 22  LEU 22  45  45  LEU LEU A . n 
A 1 23  GLY 23  46  46  GLY GLY A . n 
A 1 24  VAL 24  47  47  VAL VAL A . n 
A 1 25  ALA 25  48  48  ALA ALA A . n 
A 1 26  LEU 26  49  49  LEU LEU A . n 
A 1 27  ILE 27  50  50  ILE ILE A . n 
A 1 28  ASN 28  51  51  ASN ASN A . n 
A 1 29  THR 29  52  52  THR THR A . n 
A 1 30  ALA 30  53  53  ALA ALA A . n 
A 1 31  ASP 31  54  54  ASP ASP A . n 
A 1 32  ASN 32  55  55  ASN ASN A . n 
A 1 33  SER 33  56  56  SER SER A . n 
A 1 34  GLN 34  57  57  GLN GLN A . n 
A 1 35  ILE 35  58  58  ILE ILE A . n 
A 1 36  LEU 36  59  59  LEU LEU A . n 
A 1 37  TYR 37  60  60  TYR TYR A . n 
A 1 38  ARG 38  61  61  ARG ARG A . n 
A 1 39  ALA 39  62  62  ALA ALA A . n 
A 1 40  ASP 40  63  63  ASP ASP A . n 
A 1 41  GLU 41  64  64  GLU GLU A . n 
A 1 42  ARG 42  65  65  ARG ARG A . n 
A 1 43  PHE 43  66  66  PHE PHE A . n 
A 1 44  ALA 44  67  67  ALA ALA A . n 
A 1 45  MET 45  68  68  MET MET A . n 
A 1 46  CYS 46  69  69  CYS CYS A . n 
A 1 47  SER 47  70  70  SER SER A . n 
A 1 48  THR 48  71  71  THR THR A . n 
A 1 49  SER 49  72  72  SER SER A . n 
A 1 50  LYS 50  73  73  LYS LYS A . n 
A 1 51  VAL 51  74  74  VAL VAL A . n 
A 1 52  MET 52  75  75  MET MET A . n 
A 1 53  ALA 53  76  76  ALA ALA A . n 
A 1 54  ALA 54  77  77  ALA ALA A . n 
A 1 55  ALA 55  78  78  ALA ALA A . n 
A 1 56  ALA 56  79  79  ALA ALA A . n 
A 1 57  VAL 57  80  80  VAL VAL A . n 
A 1 58  LEU 58  81  81  LEU LEU A . n 
A 1 59  LYS 59  82  82  LYS LYS A . n 
A 1 60  LYS 60  83  83  LYS LYS A . n 
A 1 61  SER 61  84  84  SER SER A . n 
A 1 62  GLU 62  85  85  GLU GLU A . n 
A 1 63  SER 63  86  86  SER SER A . n 
A 1 64  GLU 64  87  87  GLU GLU A . n 
A 1 65  PRO 65  88  88  PRO PRO A . n 
A 1 66  ASN 66  89  89  ASN ASN A . n 
A 1 67  LEU 67  90  90  LEU LEU A . n 
A 1 68  LEU 68  91  91  LEU LEU A . n 
A 1 69  ASN 69  92  92  ASN ASN A . n 
A 1 70  GLN 70  93  93  GLN GLN A . n 
A 1 71  ARG 71  94  94  ARG ARG A . n 
A 1 72  VAL 72  95  95  VAL VAL A . n 
A 1 73  GLU 73  96  96  GLU GLU A . n 
A 1 74  ILE 74  97  97  ILE ILE A . n 
A 1 75  LYS 75  98  98  LYS LYS A . n 
A 1 76  LYS 76  99  99  LYS LYS A . n 
A 1 77  SER 77  100 100 SER SER A . n 
A 1 78  ASP 78  101 101 ASP ASP A . n 
A 1 79  LEU 79  102 102 LEU LEU A . n 
A 1 80  VAL 80  103 103 VAL VAL A . n 
A 1 81  ASN 81  104 104 ASN ASN A . n 
A 1 82  TYR 82  105 105 TYR TYR A . n 
A 1 83  ASN 83  106 106 ASN ASN A . n 
A 1 84  PRO 84  107 107 PRO PRO A . n 
A 1 85  ILE 85  108 108 ILE ILE A . n 
A 1 86  ALA 86  109 109 ALA ALA A . n 
A 1 87  GLU 87  110 110 GLU GLU A . n 
A 1 88  LYS 88  111 111 LYS LYS A . n 
A 1 89  HIS 89  112 112 HIS HIS A . n 
A 1 90  VAL 90  113 113 VAL VAL A . n 
A 1 91  ASN 91  114 114 ASN ASN A . n 
A 1 92  GLY 92  115 115 GLY GLY A . n 
A 1 93  THR 93  116 116 THR THR A . n 
A 1 94  MET 94  117 117 MET MET A . n 
A 1 95  SER 95  118 118 SER SER A . n 
A 1 96  LEU 96  119 119 LEU LEU A . n 
A 1 97  ALA 97  120 120 ALA ALA A . n 
A 1 98  GLU 98  121 121 GLU GLU A . n 
A 1 99  LEU 99  122 122 LEU LEU A . n 
A 1 100 SER 100 123 123 SER SER A . n 
A 1 101 ALA 101 124 124 ALA ALA A . n 
A 1 102 ALA 102 125 125 ALA ALA A . n 
A 1 103 ALA 103 126 126 ALA ALA A . n 
A 1 104 LEU 104 127 127 LEU LEU A . n 
A 1 105 GLN 105 128 128 GLN GLN A . n 
A 1 106 TYR 106 129 129 TYR TYR A . n 
A 1 107 SER 107 130 130 SER SER A . n 
A 1 108 ASP 108 131 131 ASP ASP A . n 
A 1 109 ASN 109 132 132 ASN ASN A . n 
A 1 110 VAL 110 133 133 VAL VAL A . n 
A 1 111 ALA 111 134 134 ALA ALA A . n 
A 1 112 MET 112 135 135 MET MET A . n 
A 1 113 ASN 113 136 136 ASN ASN A . n 
A 1 114 LYS 114 137 137 LYS LYS A . n 
A 1 115 LEU 115 138 138 LEU LEU A . n 
A 1 116 ILE 116 139 139 ILE ILE A . n 
A 1 117 ALA 117 140 140 ALA ALA A . n 
A 1 118 HIS 118 141 141 HIS HIS A . n 
A 1 119 VAL 119 142 142 VAL VAL A . n 
A 1 120 GLY 120 143 143 GLY GLY A . n 
A 1 121 GLY 121 144 144 GLY GLY A . n 
A 1 122 PRO 122 145 145 PRO PRO A . n 
A 1 123 ALA 123 146 146 ALA ALA A . n 
A 1 124 SER 124 147 147 SER SER A . n 
A 1 125 VAL 125 148 148 VAL VAL A . n 
A 1 126 THR 126 149 149 THR THR A . n 
A 1 127 ALA 127 150 150 ALA ALA A . n 
A 1 128 PHE 128 151 151 PHE PHE A . n 
A 1 129 ALA 129 152 152 ALA ALA A . n 
A 1 130 ARG 130 153 153 ARG ARG A . n 
A 1 131 GLN 131 154 154 GLN GLN A . n 
A 1 132 LEU 132 155 155 LEU LEU A . n 
A 1 133 GLY 133 156 156 GLY GLY A . n 
A 1 134 ASP 134 157 157 ASP ASP A . n 
A 1 135 GLU 135 158 158 GLU GLU A . n 
A 1 136 THR 136 159 159 THR THR A . n 
A 1 137 PHE 137 160 160 PHE PHE A . n 
A 1 138 ARG 138 161 161 ARG ARG A . n 
A 1 139 LEU 139 162 162 LEU LEU A . n 
A 1 140 ASP 140 163 163 ASP ASP A . n 
A 1 141 ARG 141 164 164 ARG ARG A . n 
A 1 142 THR 142 165 165 THR THR A . n 
A 1 143 GLU 143 166 166 GLU GLU A . n 
A 1 144 PRO 144 167 167 PRO PRO A . n 
A 1 145 THR 145 168 168 THR THR A . n 
A 1 146 LEU 146 169 169 LEU LEU A . n 
A 1 147 ASN 147 170 170 ASN ASN A . n 
A 1 148 THR 148 171 171 THR THR A . n 
A 1 149 ALA 149 172 172 ALA ALA A . n 
A 1 150 ILE 150 173 173 ILE ILE A . n 
A 1 151 PRO 151 174 174 PRO PRO A . n 
A 1 152 GLY 152 175 175 GLY GLY A . n 
A 1 153 ASP 153 176 176 ASP ASP A . n 
A 1 154 PRO 154 177 177 PRO PRO A . n 
A 1 155 ARG 155 178 178 ARG ARG A . n 
A 1 156 ASP 156 179 179 ASP ASP A . n 
A 1 157 THR 157 180 180 THR THR A . n 
A 1 158 THR 158 181 181 THR THR A . n 
A 1 159 SER 159 182 182 SER SER A . n 
A 1 160 PRO 160 183 183 PRO PRO A . n 
A 1 161 ARG 161 184 184 ARG ARG A . n 
A 1 162 ALA 162 185 185 ALA ALA A . n 
A 1 163 MET 163 186 186 MET MET A . n 
A 1 164 ALA 164 187 187 ALA ALA A . n 
A 1 165 GLN 165 188 188 GLN GLN A . n 
A 1 166 THR 166 189 189 THR THR A . n 
A 1 167 LEU 167 190 190 LEU LEU A . n 
A 1 168 ARG 168 191 191 ARG ARG A . n 
A 1 169 ASN 169 192 192 ASN ASN A . n 
A 1 170 LEU 170 193 193 LEU LEU A . n 
A 1 171 THR 171 194 194 THR THR A . n 
A 1 172 LEU 172 195 195 LEU LEU A . n 
A 1 173 GLY 173 196 196 GLY GLY A . n 
A 1 174 LYS 174 197 197 LYS LYS A . n 
A 1 175 ALA 175 198 198 ALA ALA A . n 
A 1 176 LEU 176 199 199 LEU LEU A . n 
A 1 177 GLY 177 200 200 GLY GLY A . n 
A 1 178 ASP 178 201 201 ASP ASP A . n 
A 1 179 SER 179 202 202 SER SER A . n 
A 1 180 GLN 180 203 203 GLN GLN A . n 
A 1 181 ARG 181 204 204 ARG ARG A . n 
A 1 182 ALA 182 205 205 ALA ALA A . n 
A 1 183 GLN 183 206 206 GLN GLN A . n 
A 1 184 LEU 184 207 207 LEU LEU A . n 
A 1 185 VAL 185 208 208 VAL VAL A . n 
A 1 186 THR 186 209 209 THR THR A . n 
A 1 187 TRP 187 210 210 TRP TRP A . n 
A 1 188 MET 188 211 211 MET MET A . n 
A 1 189 LYS 189 212 212 LYS LYS A . n 
A 1 190 GLY 190 213 213 GLY GLY A . n 
A 1 191 ASN 191 214 214 ASN ASN A . n 
A 1 192 THR 192 215 215 THR THR A . n 
A 1 193 THR 193 216 216 THR THR A . n 
A 1 194 GLY 194 217 217 GLY GLY A . n 
A 1 195 ALA 195 218 218 ALA ALA A . n 
A 1 196 ALA 196 219 219 ALA ALA A . n 
A 1 197 SER 197 220 220 SER SER A . n 
A 1 198 ILE 198 221 221 ILE ILE A . n 
A 1 199 GLN 199 222 222 GLN GLN A . n 
A 1 200 ALA 200 223 223 ALA ALA A . n 
A 1 201 GLY 201 224 224 GLY GLY A . n 
A 1 202 LEU 202 225 225 LEU LEU A . n 
A 1 203 PRO 203 226 226 PRO PRO A . n 
A 1 204 ALA 204 227 227 ALA ALA A . n 
A 1 205 SER 205 228 228 SER SER A . n 
A 1 206 TRP 206 229 229 TRP TRP A . n 
A 1 207 VAL 207 230 230 VAL VAL A . n 
A 1 208 VAL 208 231 231 VAL VAL A . n 
A 1 209 GLY 209 232 232 GLY GLY A . n 
A 1 210 ASP 210 233 233 ASP ASP A . n 
A 1 211 LYS 211 234 234 LYS LYS A . n 
A 1 212 THR 212 235 235 THR THR A . n 
A 1 213 GLY 213 236 236 GLY GLY A . n 
A 1 214 SER 214 237 237 SER SER A . n 
A 1 215 GLY 215 238 238 GLY GLY A . n 
A 1 216 GLY 216 239 239 GLY GLY A . n 
A 1 217 TYR 217 240 240 TYR TYR A . n 
A 1 218 GLY 218 241 241 GLY GLY A . n 
A 1 219 THR 219 242 242 THR THR A . n 
A 1 220 THR 220 243 243 THR THR A . n 
A 1 221 ASN 221 244 244 ASN ASN A . n 
A 1 222 ASP 222 245 245 ASP ASP A . n 
A 1 223 ILE 223 246 246 ILE ILE A . n 
A 1 224 ALA 224 247 247 ALA ALA A . n 
A 1 225 VAL 225 248 248 VAL VAL A . n 
A 1 226 ILE 226 249 249 ILE ILE A . n 
A 1 227 TRP 227 250 250 TRP TRP A . n 
A 1 228 PRO 228 251 251 PRO PRO A . n 
A 1 229 LYS 229 252 252 LYS LYS A . n 
A 1 230 ASP 230 253 253 ASP ASP A . n 
A 1 231 ARG 231 254 254 ARG ARG A . n 
A 1 232 ALA 232 255 255 ALA ALA A . n 
A 1 233 PRO 233 256 256 PRO PRO A . n 
A 1 234 LEU 234 257 257 LEU LEU A . n 
A 1 235 ILE 235 258 258 ILE ILE A . n 
A 1 236 LEU 236 259 259 LEU LEU A . n 
A 1 237 VAL 237 260 260 VAL VAL A . n 
A 1 238 THR 238 261 261 THR THR A . n 
A 1 239 TYR 239 262 262 TYR TYR A . n 
A 1 240 PHE 240 263 263 PHE PHE A . n 
A 1 241 THR 241 264 264 THR THR A . n 
A 1 242 GLN 242 265 265 GLN GLN A . n 
A 1 243 PRO 243 266 266 PRO PRO A . n 
A 1 244 GLN 244 267 267 GLN GLN A . n 
A 1 245 PRO 245 268 268 PRO PRO A . n 
A 1 246 LYS 246 269 269 LYS LYS A . n 
A 1 247 ALA 247 270 270 ALA ALA A . n 
A 1 248 GLU 248 271 271 GLU GLU A . n 
A 1 249 SER 249 272 272 SER SER A . n 
A 1 250 ARG 250 273 273 ARG ARG A . n 
A 1 251 ARG 251 274 274 ARG ARG A . n 
A 1 252 ASP 252 275 275 ASP ASP A . n 
A 1 253 VAL 253 276 276 VAL VAL A . n 
A 1 254 LEU 254 277 277 LEU LEU A . n 
A 1 255 ALA 255 278 278 ALA ALA A . n 
A 1 256 SER 256 279 279 SER SER A . n 
A 1 257 ALA 257 280 280 ALA ALA A . n 
A 1 258 ALA 258 281 281 ALA ALA A . n 
A 1 259 LYS 259 282 282 LYS LYS A . n 
A 1 260 ILE 260 283 283 ILE ILE A . n 
A 1 261 VAL 261 284 284 VAL VAL A . n 
A 1 262 THR 262 285 285 THR THR A . n 
A 1 263 ASP 263 286 286 ASP ASP A . n 
A 1 264 GLY 264 287 287 GLY GLY A . n 
A 1 265 LEU 265 288 288 LEU LEU A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        6M9 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   6M9 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 6M9 1   301 301 6M9 A29 A . 
C 3 DMS 1   302 302 DMS DMS A . 
D 4 GOL 1   303 303 GOL GOL A . 
E 3 DMS 1   304 304 DMS DMS A . 
F 5 SO4 1   305 1   SO4 SO4 A . 
G 5 SO4 1   306 2   SO4 SO4 A . 
H 5 SO4 1   307 4   SO4 SO4 A . 
I 5 SO4 1   308 5   SO4 SO4 A . 
J 5 SO4 1   309 6   SO4 SO4 A . 
K 6 CL  1   310 1   CL  CL  A . 
L 7 NA  1   311 1   NA  NA  A . 
M 7 NA  1   312 2   NA  NA  A . 
N 7 NA  1   313 3   NA  NA  A . 
O 5 SO4 1   314 402 SO4 SO4 A . 
P 8 HOH 1   401 157 HOH HOH A . 
P 8 HOH 2   402 261 HOH HOH A . 
P 8 HOH 3   403 279 HOH HOH A . 
P 8 HOH 4   404 173 HOH HOH A . 
P 8 HOH 5   405 159 HOH HOH A . 
P 8 HOH 6   406 185 HOH HOH A . 
P 8 HOH 7   407 203 HOH HOH A . 
P 8 HOH 8   408 156 HOH HOH A . 
P 8 HOH 9   409 187 HOH HOH A . 
P 8 HOH 10  410 80  HOH HOH A . 
P 8 HOH 11  411 250 HOH HOH A . 
P 8 HOH 12  412 316 HOH HOH A . 
P 8 HOH 13  413 318 HOH HOH A . 
P 8 HOH 14  414 338 HOH HOH A . 
P 8 HOH 15  415 153 HOH HOH A . 
P 8 HOH 16  416 183 HOH HOH A . 
P 8 HOH 17  417 189 HOH HOH A . 
P 8 HOH 18  418 232 HOH HOH A . 
P 8 HOH 19  419 225 HOH HOH A . 
P 8 HOH 20  420 292 HOH HOH A . 
P 8 HOH 21  421 55  HOH HOH A . 
P 8 HOH 22  422 171 HOH HOH A . 
P 8 HOH 23  423 227 HOH HOH A . 
P 8 HOH 24  424 154 HOH HOH A . 
P 8 HOH 25  425 168 HOH HOH A . 
P 8 HOH 26  426 172 HOH HOH A . 
P 8 HOH 27  427 162 HOH HOH A . 
P 8 HOH 28  428 317 HOH HOH A . 
P 8 HOH 29  429 266 HOH HOH A . 
P 8 HOH 30  430 282 HOH HOH A . 
P 8 HOH 31  431 346 HOH HOH A . 
P 8 HOH 32  432 264 HOH HOH A . 
P 8 HOH 33  433 161 HOH HOH A . 
P 8 HOH 34  434 304 HOH HOH A . 
P 8 HOH 35  435 52  HOH HOH A . 
P 8 HOH 36  436 35  HOH HOH A . 
P 8 HOH 37  437 114 HOH HOH A . 
P 8 HOH 38  438 192 HOH HOH A . 
P 8 HOH 39  439 44  HOH HOH A . 
P 8 HOH 40  440 71  HOH HOH A . 
P 8 HOH 41  441 82  HOH HOH A . 
P 8 HOH 42  442 234 HOH HOH A . 
P 8 HOH 43  443 39  HOH HOH A . 
P 8 HOH 44  444 287 HOH HOH A . 
P 8 HOH 45  445 109 HOH HOH A . 
P 8 HOH 46  446 26  HOH HOH A . 
P 8 HOH 47  447 17  HOH HOH A . 
P 8 HOH 48  448 233 HOH HOH A . 
P 8 HOH 49  449 8   HOH HOH A . 
P 8 HOH 50  450 11  HOH HOH A . 
P 8 HOH 51  451 65  HOH HOH A . 
P 8 HOH 52  452 18  HOH HOH A . 
P 8 HOH 53  453 105 HOH HOH A . 
P 8 HOH 54  454 69  HOH HOH A . 
P 8 HOH 55  455 10  HOH HOH A . 
P 8 HOH 56  456 6   HOH HOH A . 
P 8 HOH 57  457 178 HOH HOH A . 
P 8 HOH 58  458 16  HOH HOH A . 
P 8 HOH 59  459 99  HOH HOH A . 
P 8 HOH 60  460 30  HOH HOH A . 
P 8 HOH 61  461 84  HOH HOH A . 
P 8 HOH 62  462 51  HOH HOH A . 
P 8 HOH 63  463 283 HOH HOH A . 
P 8 HOH 64  464 61  HOH HOH A . 
P 8 HOH 65  465 36  HOH HOH A . 
P 8 HOH 66  466 200 HOH HOH A . 
P 8 HOH 67  467 21  HOH HOH A . 
P 8 HOH 68  468 181 HOH HOH A . 
P 8 HOH 69  469 43  HOH HOH A . 
P 8 HOH 70  470 289 HOH HOH A . 
P 8 HOH 71  471 33  HOH HOH A . 
P 8 HOH 72  472 14  HOH HOH A . 
P 8 HOH 73  473 270 HOH HOH A . 
P 8 HOH 74  474 158 HOH HOH A . 
P 8 HOH 75  475 23  HOH HOH A . 
P 8 HOH 76  476 70  HOH HOH A . 
P 8 HOH 77  477 12  HOH HOH A . 
P 8 HOH 78  478 101 HOH HOH A . 
P 8 HOH 79  479 3   HOH HOH A . 
P 8 HOH 80  480 7   HOH HOH A . 
P 8 HOH 81  481 312 HOH HOH A . 
P 8 HOH 82  482 330 HOH HOH A . 
P 8 HOH 83  483 22  HOH HOH A . 
P 8 HOH 84  484 13  HOH HOH A . 
P 8 HOH 85  485 133 HOH HOH A . 
P 8 HOH 86  486 321 HOH HOH A . 
P 8 HOH 87  487 128 HOH HOH A . 
P 8 HOH 88  488 5   HOH HOH A . 
P 8 HOH 89  489 81  HOH HOH A . 
P 8 HOH 90  490 42  HOH HOH A . 
P 8 HOH 91  491 121 HOH HOH A . 
P 8 HOH 92  492 32  HOH HOH A . 
P 8 HOH 93  493 213 HOH HOH A . 
P 8 HOH 94  494 145 HOH HOH A . 
P 8 HOH 95  495 24  HOH HOH A . 
P 8 HOH 96  496 211 HOH HOH A . 
P 8 HOH 97  497 62  HOH HOH A . 
P 8 HOH 98  498 167 HOH HOH A . 
P 8 HOH 99  499 15  HOH HOH A . 
P 8 HOH 100 500 144 HOH HOH A . 
P 8 HOH 101 501 34  HOH HOH A . 
P 8 HOH 102 502 329 HOH HOH A . 
P 8 HOH 103 503 77  HOH HOH A . 
P 8 HOH 104 504 27  HOH HOH A . 
P 8 HOH 105 505 4   HOH HOH A . 
P 8 HOH 106 506 103 HOH HOH A . 
P 8 HOH 107 507 150 HOH HOH A . 
P 8 HOH 108 508 53  HOH HOH A . 
P 8 HOH 109 509 314 HOH HOH A . 
P 8 HOH 110 510 239 HOH HOH A . 
P 8 HOH 111 511 73  HOH HOH A . 
P 8 HOH 112 512 309 HOH HOH A . 
P 8 HOH 113 513 135 HOH HOH A . 
P 8 HOH 114 514 155 HOH HOH A . 
P 8 HOH 115 515 68  HOH HOH A . 
P 8 HOH 116 516 46  HOH HOH A . 
P 8 HOH 117 517 160 HOH HOH A . 
P 8 HOH 118 518 9   HOH HOH A . 
P 8 HOH 119 519 48  HOH HOH A . 
P 8 HOH 120 520 129 HOH HOH A . 
P 8 HOH 121 521 79  HOH HOH A . 
P 8 HOH 122 522 132 HOH HOH A . 
P 8 HOH 123 523 96  HOH HOH A . 
P 8 HOH 124 524 86  HOH HOH A . 
P 8 HOH 125 525 120 HOH HOH A . 
P 8 HOH 126 526 1   HOH HOH A . 
P 8 HOH 127 527 72  HOH HOH A . 
P 8 HOH 128 528 180 HOH HOH A . 
P 8 HOH 129 529 100 HOH HOH A . 
P 8 HOH 130 530 2   HOH HOH A . 
P 8 HOH 131 531 149 HOH HOH A . 
P 8 HOH 132 532 278 HOH HOH A . 
P 8 HOH 133 533 275 HOH HOH A . 
P 8 HOH 134 534 265 HOH HOH A . 
P 8 HOH 135 535 50  HOH HOH A . 
P 8 HOH 136 536 60  HOH HOH A . 
P 8 HOH 137 537 140 HOH HOH A . 
P 8 HOH 138 538 98  HOH HOH A . 
P 8 HOH 139 539 93  HOH HOH A . 
P 8 HOH 140 540 218 HOH HOH A . 
P 8 HOH 141 541 175 HOH HOH A . 
P 8 HOH 142 542 58  HOH HOH A . 
P 8 HOH 143 543 107 HOH HOH A . 
P 8 HOH 144 544 246 HOH HOH A . 
P 8 HOH 145 545 45  HOH HOH A . 
P 8 HOH 146 546 273 HOH HOH A . 
P 8 HOH 147 547 139 HOH HOH A . 
P 8 HOH 148 548 248 HOH HOH A . 
P 8 HOH 149 549 78  HOH HOH A . 
P 8 HOH 150 550 49  HOH HOH A . 
P 8 HOH 151 551 272 HOH HOH A . 
P 8 HOH 152 552 92  HOH HOH A . 
P 8 HOH 153 553 25  HOH HOH A . 
P 8 HOH 154 554 116 HOH HOH A . 
P 8 HOH 155 555 310 HOH HOH A . 
P 8 HOH 156 556 64  HOH HOH A . 
P 8 HOH 157 557 83  HOH HOH A . 
P 8 HOH 158 558 57  HOH HOH A . 
P 8 HOH 159 559 125 HOH HOH A . 
P 8 HOH 160 560 41  HOH HOH A . 
P 8 HOH 161 561 59  HOH HOH A . 
P 8 HOH 162 562 95  HOH HOH A . 
P 8 HOH 163 563 67  HOH HOH A . 
P 8 HOH 164 564 347 HOH HOH A . 
P 8 HOH 165 565 349 HOH HOH A . 
P 8 HOH 166 566 126 HOH HOH A . 
P 8 HOH 167 567 136 HOH HOH A . 
P 8 HOH 168 568 313 HOH HOH A . 
P 8 HOH 169 569 88  HOH HOH A . 
P 8 HOH 170 570 74  HOH HOH A . 
P 8 HOH 171 571 335 HOH HOH A . 
P 8 HOH 172 572 191 HOH HOH A . 
P 8 HOH 173 573 40  HOH HOH A . 
P 8 HOH 174 574 97  HOH HOH A . 
P 8 HOH 175 575 102 HOH HOH A . 
P 8 HOH 176 576 54  HOH HOH A . 
P 8 HOH 177 577 112 HOH HOH A . 
P 8 HOH 178 578 20  HOH HOH A . 
P 8 HOH 179 579 324 HOH HOH A . 
P 8 HOH 180 580 89  HOH HOH A . 
P 8 HOH 181 581 280 HOH HOH A . 
P 8 HOH 182 582 193 HOH HOH A . 
P 8 HOH 183 583 323 HOH HOH A . 
P 8 HOH 184 584 207 HOH HOH A . 
P 8 HOH 185 585 28  HOH HOH A . 
P 8 HOH 186 586 269 HOH HOH A . 
P 8 HOH 187 587 130 HOH HOH A . 
P 8 HOH 188 588 212 HOH HOH A . 
P 8 HOH 189 589 119 HOH HOH A . 
P 8 HOH 190 590 94  HOH HOH A . 
P 8 HOH 191 591 210 HOH HOH A . 
P 8 HOH 192 592 141 HOH HOH A . 
P 8 HOH 193 593 198 HOH HOH A . 
P 8 HOH 194 594 163 HOH HOH A . 
P 8 HOH 195 595 19  HOH HOH A . 
P 8 HOH 196 596 336 HOH HOH A . 
P 8 HOH 197 597 38  HOH HOH A . 
P 8 HOH 198 598 122 HOH HOH A . 
P 8 HOH 199 599 214 HOH HOH A . 
P 8 HOH 200 600 31  HOH HOH A . 
P 8 HOH 201 601 91  HOH HOH A . 
P 8 HOH 202 602 350 HOH HOH A . 
P 8 HOH 203 603 29  HOH HOH A . 
P 8 HOH 204 604 325 HOH HOH A . 
P 8 HOH 205 605 108 HOH HOH A . 
P 8 HOH 206 606 76  HOH HOH A . 
P 8 HOH 207 607 87  HOH HOH A . 
P 8 HOH 208 608 206 HOH HOH A . 
P 8 HOH 209 609 182 HOH HOH A . 
P 8 HOH 210 610 152 HOH HOH A . 
P 8 HOH 211 611 142 HOH HOH A . 
P 8 HOH 212 612 143 HOH HOH A . 
P 8 HOH 213 613 256 HOH HOH A . 
P 8 HOH 214 614 47  HOH HOH A . 
P 8 HOH 215 615 340 HOH HOH A . 
P 8 HOH 216 616 326 HOH HOH A . 
P 8 HOH 217 617 202 HOH HOH A . 
P 8 HOH 218 618 177 HOH HOH A . 
P 8 HOH 219 619 221 HOH HOH A . 
P 8 HOH 220 620 186 HOH HOH A . 
P 8 HOH 221 621 341 HOH HOH A . 
P 8 HOH 222 622 302 HOH HOH A . 
P 8 HOH 223 623 342 HOH HOH A . 
P 8 HOH 224 624 194 HOH HOH A . 
P 8 HOH 225 625 294 HOH HOH A . 
P 8 HOH 226 626 37  HOH HOH A . 
P 8 HOH 227 627 199 HOH HOH A . 
P 8 HOH 228 628 277 HOH HOH A . 
P 8 HOH 229 629 166 HOH HOH A . 
P 8 HOH 230 630 238 HOH HOH A . 
P 8 HOH 231 631 260 HOH HOH A . 
P 8 HOH 232 632 220 HOH HOH A . 
P 8 HOH 233 633 320 HOH HOH A . 
P 8 HOH 234 634 131 HOH HOH A . 
P 8 HOH 235 635 151 HOH HOH A . 
P 8 HOH 236 636 230 HOH HOH A . 
P 8 HOH 237 637 251 HOH HOH A . 
P 8 HOH 238 638 334 HOH HOH A . 
P 8 HOH 239 639 258 HOH HOH A . 
P 8 HOH 240 640 319 HOH HOH A . 
P 8 HOH 241 641 263 HOH HOH A . 
P 8 HOH 242 642 296 HOH HOH A . 
P 8 HOH 243 643 205 HOH HOH A . 
P 8 HOH 244 644 90  HOH HOH A . 
P 8 HOH 245 645 339 HOH HOH A . 
P 8 HOH 246 646 332 HOH HOH A . 
P 8 HOH 247 647 243 HOH HOH A . 
P 8 HOH 248 648 252 HOH HOH A . 
P 8 HOH 249 649 237 HOH HOH A . 
P 8 HOH 250 650 298 HOH HOH A . 
P 8 HOH 251 651 305 HOH HOH A . 
P 8 HOH 252 652 343 HOH HOH A . 
P 8 HOH 253 653 228 HOH HOH A . 
P 8 HOH 254 654 348 HOH HOH A . 
P 8 HOH 255 655 195 HOH HOH A . 
P 8 HOH 256 656 249 HOH HOH A . 
P 8 HOH 257 657 137 HOH HOH A . 
P 8 HOH 258 658 308 HOH HOH A . 
P 8 HOH 259 659 123 HOH HOH A . 
P 8 HOH 260 660 164 HOH HOH A . 
P 8 HOH 261 661 322 HOH HOH A . 
P 8 HOH 262 662 170 HOH HOH A . 
P 8 HOH 263 663 127 HOH HOH A . 
P 8 HOH 264 664 147 HOH HOH A . 
P 8 HOH 265 665 63  HOH HOH A . 
P 8 HOH 266 666 75  HOH HOH A . 
P 8 HOH 267 667 333 HOH HOH A . 
P 8 HOH 268 668 328 HOH HOH A . 
P 8 HOH 269 669 56  HOH HOH A . 
P 8 HOH 270 670 115 HOH HOH A . 
P 8 HOH 271 671 179 HOH HOH A . 
P 8 HOH 272 672 117 HOH HOH A . 
P 8 HOH 273 673 223 HOH HOH A . 
P 8 HOH 274 674 201 HOH HOH A . 
P 8 HOH 275 675 255 HOH HOH A . 
P 8 HOH 276 676 184 HOH HOH A . 
P 8 HOH 277 677 244 HOH HOH A . 
P 8 HOH 278 678 66  HOH HOH A . 
P 8 HOH 279 679 311 HOH HOH A . 
P 8 HOH 280 680 262 HOH HOH A . 
P 8 HOH 281 681 315 HOH HOH A . 
P 8 HOH 282 682 327 HOH HOH A . 
P 8 HOH 283 683 174 HOH HOH A . 
P 8 HOH 284 684 235 HOH HOH A . 
P 8 HOH 285 685 247 HOH HOH A . 
P 8 HOH 286 686 209 HOH HOH A . 
P 8 HOH 287 687 274 HOH HOH A . 
P 8 HOH 288 688 229 HOH HOH A . 
P 8 HOH 289 689 138 HOH HOH A . 
P 8 HOH 290 690 288 HOH HOH A . 
P 8 HOH 291 691 257 HOH HOH A . 
P 8 HOH 292 692 169 HOH HOH A . 
P 8 HOH 293 693 204 HOH HOH A . 
P 8 HOH 294 694 148 HOH HOH A . 
P 8 HOH 295 695 331 HOH HOH A . 
P 8 HOH 296 696 281 HOH HOH A . 
P 8 HOH 297 697 240 HOH HOH A . 
P 8 HOH 298 698 113 HOH HOH A . 
P 8 HOH 299 699 111 HOH HOH A . 
P 8 HOH 300 700 245 HOH HOH A . 
P 8 HOH 301 701 236 HOH HOH A . 
P 8 HOH 302 702 110 HOH HOH A . 
P 8 HOH 303 703 190 HOH HOH A . 
P 8 HOH 304 704 124 HOH HOH A . 
P 8 HOH 305 705 267 HOH HOH A . 
P 8 HOH 306 706 208 HOH HOH A . 
P 8 HOH 307 707 222 HOH HOH A . 
P 8 HOH 308 708 268 HOH HOH A . 
P 8 HOH 309 709 286 HOH HOH A . 
P 8 HOH 310 710 284 HOH HOH A . 
P 8 HOH 311 711 104 HOH HOH A . 
P 8 HOH 312 712 176 HOH HOH A . 
P 8 HOH 313 713 300 HOH HOH A . 
P 8 HOH 314 714 259 HOH HOH A . 
P 8 HOH 315 715 253 HOH HOH A . 
P 8 HOH 316 716 301 HOH HOH A . 
P 8 HOH 317 717 146 HOH HOH A . 
P 8 HOH 318 718 118 HOH HOH A . 
P 8 HOH 319 719 242 HOH HOH A . 
P 8 HOH 320 720 271 HOH HOH A . 
P 8 HOH 321 721 188 HOH HOH A . 
P 8 HOH 322 722 297 HOH HOH A . 
P 8 HOH 323 723 231 HOH HOH A . 
P 8 HOH 324 724 165 HOH HOH A . 
P 8 HOH 325 725 197 HOH HOH A . 
P 8 HOH 326 726 106 HOH HOH A . 
P 8 HOH 327 727 306 HOH HOH A . 
P 8 HOH 328 728 344 HOH HOH A . 
P 8 HOH 329 729 345 HOH HOH A . 
P 8 HOH 330 730 254 HOH HOH A . 
P 8 HOH 331 731 303 HOH HOH A . 
P 8 HOH 332 732 293 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .           3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8R2Y 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     44.430 
_cell.length_a_esd                 ? 
_cell.length_b                     45.850 
_cell.length_b_esd                 ? 
_cell.length_c                     116.880 
_cell.length_c_esd                 ? 
_cell.volume                       238098.060 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8R2Y 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8R2Y 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.10 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          41.54 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '2.0 M ammonium sulphate, 0.1 M Tris 8.0' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            292.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-07-16 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.6741 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.6741 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          11.65 
_reflns.entry_id                                       8R2Y 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.03 
_reflns.d_resolution_low                               35.37 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     118620 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.034 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1.00 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.03 
_reflns_shell.d_res_low                                     1.05 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.4 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             5861 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.912 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.27 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               17.68 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8R2Y 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.03 
_refine.ls_d_res_low                             28.00 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     118208 
_refine.ls_number_reflns_R_free                  5743 
_refine.ls_number_reflns_R_work                  112465 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.60 
_refine.ls_percent_reflns_R_free                 4.86 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1354 
_refine.ls_R_factor_R_free                       0.1543 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1344 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'FOURIER SYNTHESIS' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 16.8694 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1220 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.03 
_refine_hist.d_res_low                        28.00 
_refine_hist.number_atoms_solvent             332 
_refine_hist.number_atoms_total               2346 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1956 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         58 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0063  ? 2223 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9512  ? 3044 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0778  ? 339  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0117  ? 408  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 11.5313 ? 848  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.03 1.04  . . 185 3537 95.05  . . . . 0.3583 . . . . . . . . . . . 0.3863 
'X-RAY DIFFRACTION' 1.04 1.05  . . 186 3631 98.07  . . . . 0.3369 . . . . . . . . . . . 0.3506 
'X-RAY DIFFRACTION' 1.05 1.07  . . 192 3702 99.67  . . . . 0.3118 . . . . . . . . . . . 0.3171 
'X-RAY DIFFRACTION' 1.07 1.08  . . 200 3709 99.95  . . . . 0.3028 . . . . . . . . . . . 0.3317 
'X-RAY DIFFRACTION' 1.08 1.09  . . 185 3721 99.95  . . . . 0.2742 . . . . . . . . . . . 0.3037 
'X-RAY DIFFRACTION' 1.09 1.11  . . 216 3711 99.87  . . . . 0.2657 . . . . . . . . . . . 0.2779 
'X-RAY DIFFRACTION' 1.11 1.13  . . 172 3700 99.90  . . . . 0.2415 . . . . . . . . . . . 0.2619 
'X-RAY DIFFRACTION' 1.13 1.14  . . 198 3734 99.95  . . . . 0.2350 . . . . . . . . . . . 0.2519 
'X-RAY DIFFRACTION' 1.14 1.16  . . 196 3722 99.97  . . . . 0.2221 . . . . . . . . . . . 0.2301 
'X-RAY DIFFRACTION' 1.16 1.18  . . 182 3740 99.95  . . . . 0.2062 . . . . . . . . . . . 0.2132 
'X-RAY DIFFRACTION' 1.18 1.20  . . 201 3720 100.00 . . . . 0.1980 . . . . . . . . . . . 0.2176 
'X-RAY DIFFRACTION' 1.20 1.22  . . 184 3726 99.95  . . . . 0.1918 . . . . . . . . . . . 0.1962 
'X-RAY DIFFRACTION' 1.22 1.24  . . 190 3735 99.80  . . . . 0.1826 . . . . . . . . . . . 0.2121 
'X-RAY DIFFRACTION' 1.24 1.27  . . 179 3749 99.75  . . . . 0.1695 . . . . . . . . . . . 0.1982 
'X-RAY DIFFRACTION' 1.27 1.30  . . 206 3686 99.57  . . . . 0.1617 . . . . . . . . . . . 0.1959 
'X-RAY DIFFRACTION' 1.30 1.33  . . 189 3725 99.24  . . . . 0.1554 . . . . . . . . . . . 0.1874 
'X-RAY DIFFRACTION' 1.33 1.36  . . 205 3688 98.63  . . . . 0.1539 . . . . . . . . . . . 0.1879 
'X-RAY DIFFRACTION' 1.36 1.40  . . 195 3731 99.59  . . . . 0.1340 . . . . . . . . . . . 0.1467 
'X-RAY DIFFRACTION' 1.40 1.44  . . 220 3709 99.97  . . . . 0.1217 . . . . . . . . . . . 0.1539 
'X-RAY DIFFRACTION' 1.44 1.49  . . 158 3809 100.00 . . . . 0.1098 . . . . . . . . . . . 0.1352 
'X-RAY DIFFRACTION' 1.49 1.54  . . 177 3758 100.00 . . . . 0.1026 . . . . . . . . . . . 0.1145 
'X-RAY DIFFRACTION' 1.54 1.60  . . 179 3782 99.97  . . . . 0.0999 . . . . . . . . . . . 0.1322 
'X-RAY DIFFRACTION' 1.60 1.67  . . 189 3769 99.97  . . . . 0.0974 . . . . . . . . . . . 0.1168 
'X-RAY DIFFRACTION' 1.67 1.76  . . 201 3787 100.00 . . . . 0.0983 . . . . . . . . . . . 0.1342 
'X-RAY DIFFRACTION' 1.76 1.87  . . 181 3786 100.00 . . . . 0.1007 . . . . . . . . . . . 0.1303 
'X-RAY DIFFRACTION' 1.87 2.02  . . 188 3820 99.90  . . . . 0.0991 . . . . . . . . . . . 0.1189 
'X-RAY DIFFRACTION' 2.02 2.22  . . 197 3827 99.95  . . . . 0.0992 . . . . . . . . . . . 0.1164 
'X-RAY DIFFRACTION' 2.22 2.54  . . 198 3804 99.55  . . . . 0.1024 . . . . . . . . . . . 0.1176 
'X-RAY DIFFRACTION' 2.54 3.20  . . 188 3897 99.93  . . . . 0.1173 . . . . . . . . . . . 0.1364 
'X-RAY DIFFRACTION' 3.20 28.00 . . 206 4050 99.95  . . . . 0.1379 . . . . . . . . . . . 0.1497 
# 
_struct.entry_id                     8R2Y 
_struct.title                        'Structure of CTX-M-15 complexed with benzoxaborole AK-29' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8R2Y 
_struct_keywords.text            'Inhibitor, beta-lactamase, SBL, antibiotic resistance, ANTIMICROBIAL PROTEIN' 
_struct_keywords.pdbx_keywords   'ANTIMICROBIAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 3 ? 
F N N 5 ? 
G N N 5 ? 
H N N 5 ? 
I N N 5 ? 
J N N 5 ? 
K N N 6 ? 
L N N 7 ? 
M N N 7 ? 
N N N 7 ? 
O N N 5 ? 
P N N 8 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    G3G192_KLEPN 
_struct_ref.pdbx_db_accession          G3G192 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;QTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLVNY
NPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRA
MAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ
PQPKAESRRDVLASAAKIVTDGL
;
_struct_ref.pdbx_align_begin           49 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8R2Y 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 3 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 265 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             G3G192 
_struct_ref_seq.db_align_beg                  49 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  311 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       26 
_struct_ref_seq.pdbx_auth_seq_align_end       288 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8R2Y GLY A 1 ? UNP G3G192 ? ? 'expression tag' 24 1 
1 8R2Y PRO A 2 ? UNP G3G192 ? ? 'expression tag' 25 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1780  ? 
1 MORE         -77   ? 
1 'SSA (A^2)'  11090 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 5   ? GLY A 19  ? ALA A 28  GLY A 42  1 ? 15 
HELX_P HELX_P2  AA2 CYS A 46  ? THR A 48  ? CYS A 69  THR A 71  5 ? 3  
HELX_P HELX_P3  AA3 SER A 49  ? GLU A 62  ? SER A 72  GLU A 85  1 ? 14 
HELX_P HELX_P4  AA4 LYS A 75  ? LEU A 79  ? LYS A 98  LEU A 102 5 ? 5  
HELX_P HELX_P5  AA5 ILE A 85  ? HIS A 89  ? ILE A 108 HIS A 112 5 ? 5  
HELX_P HELX_P6  AA6 LEU A 96  ? SER A 107 ? LEU A 119 SER A 130 1 ? 12 
HELX_P HELX_P7  AA7 ASP A 108 ? GLY A 120 ? ASP A 131 GLY A 143 1 ? 13 
HELX_P HELX_P8  AA8 GLY A 121 ? LEU A 132 ? GLY A 144 LEU A 155 1 ? 12 
HELX_P HELX_P9  AA9 PRO A 144 ? THR A 148 ? PRO A 167 THR A 171 5 ? 5  
HELX_P HELX_P10 AB1 SER A 159 ? LEU A 172 ? SER A 182 LEU A 195 1 ? 14 
HELX_P HELX_P11 AB2 GLY A 177 ? GLY A 190 ? GLY A 200 GLY A 213 1 ? 14 
HELX_P HELX_P12 AB3 SER A 197 ? LEU A 202 ? SER A 220 LEU A 225 5 ? 6  
HELX_P HELX_P13 AB4 ARG A 250 ? ASP A 263 ? ARG A 273 ASP A 286 1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale none ? A SER 47  OG  ? ? ? 1_555 B 6M9 . B1 A ? A SER 70  A 6M9 301 1_555 ? ? ? ? ? ? ? 1.447 ? ? 
metalc1 metalc ?    ? A ASP 134 OD2 ? ? ? 1_555 L NA  . NA ? ? A ASP 157 A NA  311 1_555 ? ? ? ? ? ? ? 2.655 ? ? 
metalc2 metalc ?    ? A THR 158 OG1 ? ? ? 1_555 L NA  . NA ? ? A THR 181 A NA  311 1_555 ? ? ? ? ? ? ? 2.717 ? ? 
metalc3 metalc ?    ? A GLY 194 O   ? ? ? 1_555 M NA  . NA ? ? A GLY 217 A NA  312 1_555 ? ? ? ? ? ? ? 2.744 ? ? 
metalc4 metalc ?    ? A THR 212 OG1 ? ? ? 1_555 N NA  . NA A ? A THR 235 A NA  313 1_555 ? ? ? ? ? ? ? 2.824 ? ? 
metalc5 metalc ?    ? A ASP 222 OD2 ? ? ? 1_555 M NA  . NA ? ? A ASP 245 A NA  312 1_555 ? ? ? ? ? ? ? 2.762 ? ? 
metalc6 metalc ?    ? B 6M9 .   O1  A ? ? 1_555 N NA  . NA A ? A 6M9 301 A NA  313 1_555 ? ? ? ? ? ? ? 2.658 ? ? 
metalc7 metalc ?    ? N NA  .   NA  A ? ? 1_555 P HOH . O  ? ? A NA  313 A HOH 709 4_445 ? ? ? ? ? ? ? 3.059 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OD2 ? A ASP 134 ? A ASP 157 ? 1_555 NA ? L NA . ? A NA 311 ? 1_555 OG1 ? A THR 158 ? A THR 181 ? 1_555 120.9 ? 
2 O   ? A GLY 194 ? A GLY 217 ? 1_555 NA ? M NA . ? A NA 312 ? 1_555 OD2 ? A ASP 222 ? A ASP 245 ? 1_555 108.3 ? 
3 OG1 ? A THR 212 ? A THR 235 ? 1_555 NA A N NA . ? A NA 313 ? 1_555 O1  A B 6M9 .   ? A 6M9 301 ? 1_555 138.8 ? 
4 OG1 ? A THR 212 ? A THR 235 ? 1_555 NA A N NA . ? A NA 313 ? 1_555 O   ? P HOH .   ? A HOH 709 ? 4_445 111.4 ? 
5 O1  A B 6M9 .   ? A 6M9 301 ? 1_555 NA A N NA . ? A NA 313 ? 1_555 O   ? P HOH .   ? A HOH 709 ? 4_445 104.3 ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      6M9 
_pdbx_modification_feature.label_asym_id                      B 
_pdbx_modification_feature.label_seq_id                       . 
_pdbx_modification_feature.label_alt_id                       A 
_pdbx_modification_feature.modified_residue_label_comp_id     SER 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      47 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       6M9 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        301 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      SER 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       70 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               B1 
_pdbx_modification_feature.modified_residue_id_linking_atom   OG 
_pdbx_modification_feature.modified_residue_id                SER 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        6M9 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Covalent chemical modification' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLU 
_struct_mon_prot_cis.label_seq_id           143 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLU 
_struct_mon_prot_cis.auth_seq_id            166 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    144 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     167 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       6.32 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 33  ? TYR A 37  ? SER A 56  TYR A 60  
AA1 2 ARG A 21  ? ASN A 28  ? ARG A 44  ASN A 51  
AA1 3 LEU A 234 ? THR A 241 ? LEU A 257 THR A 264 
AA1 4 THR A 219 ? TRP A 227 ? THR A 242 TRP A 250 
AA1 5 VAL A 207 ? GLY A 215 ? VAL A 230 GLY A 238 
AA2 1 PHE A 43  ? ALA A 44  ? PHE A 66  ALA A 67  
AA2 2 THR A 157 ? THR A 158 ? THR A 180 THR A 181 
AA3 1 ARG A 71  ? GLU A 73  ? ARG A 94  GLU A 96  
AA3 2 THR A 93  ? SER A 95  ? THR A 116 SER A 118 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O SER A 33  ? O SER A 56  N ASN A 28  ? N ASN A 51  
AA1 2 3 N GLY A 23  ? N GLY A 46  O TYR A 239 ? O TYR A 262 
AA1 3 4 O LEU A 234 ? O LEU A 257 N ILE A 226 ? N ILE A 249 
AA1 4 5 O TRP A 227 ? O TRP A 250 N VAL A 207 ? N VAL A 230 
AA2 1 2 N PHE A 43  ? N PHE A 66  O THR A 158 ? O THR A 181 
AA3 1 2 N VAL A 72  ? N VAL A 95  O MET A 94  ? O MET A 117 
# 
_pdbx_entry_details.entry_id                   8R2Y 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 OD1  A ASN 89  ? A HD22 A ASN 92  ? ? 1.47 
2  1 HH12 A ARG 204 ? B O    A HOH 408 ? ? 1.53 
3  1 OD1  A ASP 201 ? ? HH22 A ARG 204 ? B 1.58 
4  1 O    A HOH 621 ? ? O    A HOH 623 ? ? 1.65 
5  1 O    A HOH 579 ? ? O    A HOH 602 ? ? 1.68 
6  1 O    A HOH 615 ? ? O    A HOH 621 ? ? 1.86 
7  1 O    A HOH 621 ? ? O    A HOH 645 ? ? 1.88 
8  1 O    A HOH 413 ? ? O    A HOH 423 ? ? 1.89 
9  1 OD2  A ASP 286 ? B O    A HOH 401 ? ? 1.90 
10 1 O    A HOH 409 ? ? O    A HOH 634 ? ? 1.97 
11 1 O    A HOH 403 ? ? O    A HOH 550 ? ? 1.99 
12 1 O    A HOH 411 ? ? O    A HOH 582 ? ? 2.00 
13 1 O    A HOH 652 ? ? O    A HOH 728 ? ? 2.01 
14 1 O    A HOH 414 ? ? O    A HOH 623 ? ? 2.03 
15 1 OD1  A ASP 286 ? B O    A HOH 402 ? ? 2.05 
16 1 OE1  A GLN 222 ? B O    A HOH 403 ? ? 2.10 
17 1 O    A PRO 88  ? A O    A HOH 404 ? ? 2.10 
18 1 O    A HOH 587 ? ? O    A HOH 611 ? ? 2.13 
19 1 O    A HOH 661 ? ? O    A HOH 712 ? ? 2.13 
20 1 O    A HOH 532 ? ? O    A HOH 716 ? ? 2.14 
21 1 O    A HOH 403 ? ? O    A HOH 649 ? ? 2.14 
22 1 O    A HOH 598 ? ? O    A HOH 705 ? ? 2.15 
23 1 O    A HOH 728 ? ? O    A HOH 729 ? ? 2.15 
24 1 O    A HOH 548 ? ? O    A HOH 675 ? ? 2.16 
25 1 O    A HOH 682 ? ? O    A HOH 685 ? ? 2.17 
26 1 O    A HOH 433 ? ? O    A HOH 693 ? ? 2.18 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 O  A HOH 409 ? ? 1_555 O A HOH 718 ? ? 3_545 1.83 
2 1 O2 A SO4 314 ? B 1_555 O A HOH 709 ? ? 4_445 1.84 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 CYS A 69  ? ? 49.84   -138.55 
2 1 VAL A 103 ? ? -124.12 -139.58 
3 1 SER A 220 ? ? -104.62 -121.73 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 730 ? 5.85 . 
2 1 O ? A HOH 731 ? 5.96 . 
3 1 O ? A HOH 732 ? 6.15 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLY 24 ? A GLY 1 
2 1 Y 1 A PRO 25 ? A PRO 2 
3 1 Y 1 A GLN 26 ? A GLN 3 
4 1 Y 1 A THR 27 ? A THR 4 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
6M9 C1   C  Y N 1   
6M9 C2   C  Y N 2   
6M9 C3   C  Y N 3   
6M9 C4   C  Y N 4   
6M9 C5   C  Y N 5   
6M9 C6   C  Y N 6   
6M9 C7   C  N N 7   
6M9 O1   O  N N 8   
6M9 O2   O  N N 9   
6M9 B1   B  N N 10  
6M9 H1   H  N N 11  
6M9 H2   H  N N 12  
6M9 H3   H  N N 13  
6M9 H4   H  N N 14  
6M9 H5   H  N N 15  
6M9 H6   H  N N 16  
6M9 H7   H  N N 17  
ALA N    N  N N 18  
ALA CA   C  N S 19  
ALA C    C  N N 20  
ALA O    O  N N 21  
ALA CB   C  N N 22  
ALA OXT  O  N N 23  
ALA H    H  N N 24  
ALA H2   H  N N 25  
ALA HA   H  N N 26  
ALA HB1  H  N N 27  
ALA HB2  H  N N 28  
ALA HB3  H  N N 29  
ALA HXT  H  N N 30  
ARG N    N  N N 31  
ARG CA   C  N S 32  
ARG C    C  N N 33  
ARG O    O  N N 34  
ARG CB   C  N N 35  
ARG CG   C  N N 36  
ARG CD   C  N N 37  
ARG NE   N  N N 38  
ARG CZ   C  N N 39  
ARG NH1  N  N N 40  
ARG NH2  N  N N 41  
ARG OXT  O  N N 42  
ARG H    H  N N 43  
ARG H2   H  N N 44  
ARG HA   H  N N 45  
ARG HB2  H  N N 46  
ARG HB3  H  N N 47  
ARG HG2  H  N N 48  
ARG HG3  H  N N 49  
ARG HD2  H  N N 50  
ARG HD3  H  N N 51  
ARG HE   H  N N 52  
ARG HH11 H  N N 53  
ARG HH12 H  N N 54  
ARG HH21 H  N N 55  
ARG HH22 H  N N 56  
ARG HXT  H  N N 57  
ASN N    N  N N 58  
ASN CA   C  N S 59  
ASN C    C  N N 60  
ASN O    O  N N 61  
ASN CB   C  N N 62  
ASN CG   C  N N 63  
ASN OD1  O  N N 64  
ASN ND2  N  N N 65  
ASN OXT  O  N N 66  
ASN H    H  N N 67  
ASN H2   H  N N 68  
ASN HA   H  N N 69  
ASN HB2  H  N N 70  
ASN HB3  H  N N 71  
ASN HD21 H  N N 72  
ASN HD22 H  N N 73  
ASN HXT  H  N N 74  
ASP N    N  N N 75  
ASP CA   C  N S 76  
ASP C    C  N N 77  
ASP O    O  N N 78  
ASP CB   C  N N 79  
ASP CG   C  N N 80  
ASP OD1  O  N N 81  
ASP OD2  O  N N 82  
ASP OXT  O  N N 83  
ASP H    H  N N 84  
ASP H2   H  N N 85  
ASP HA   H  N N 86  
ASP HB2  H  N N 87  
ASP HB3  H  N N 88  
ASP HD2  H  N N 89  
ASP HXT  H  N N 90  
CL  CL   CL N N 91  
CYS N    N  N N 92  
CYS CA   C  N R 93  
CYS C    C  N N 94  
CYS O    O  N N 95  
CYS CB   C  N N 96  
CYS SG   S  N N 97  
CYS OXT  O  N N 98  
CYS H    H  N N 99  
CYS H2   H  N N 100 
CYS HA   H  N N 101 
CYS HB2  H  N N 102 
CYS HB3  H  N N 103 
CYS HG   H  N N 104 
CYS HXT  H  N N 105 
DMS S    S  N N 106 
DMS O    O  N N 107 
DMS C1   C  N N 108 
DMS C2   C  N N 109 
DMS H11  H  N N 110 
DMS H12  H  N N 111 
DMS H13  H  N N 112 
DMS H21  H  N N 113 
DMS H22  H  N N 114 
DMS H23  H  N N 115 
GLN N    N  N N 116 
GLN CA   C  N S 117 
GLN C    C  N N 118 
GLN O    O  N N 119 
GLN CB   C  N N 120 
GLN CG   C  N N 121 
GLN CD   C  N N 122 
GLN OE1  O  N N 123 
GLN NE2  N  N N 124 
GLN OXT  O  N N 125 
GLN H    H  N N 126 
GLN H2   H  N N 127 
GLN HA   H  N N 128 
GLN HB2  H  N N 129 
GLN HB3  H  N N 130 
GLN HG2  H  N N 131 
GLN HG3  H  N N 132 
GLN HE21 H  N N 133 
GLN HE22 H  N N 134 
GLN HXT  H  N N 135 
GLU N    N  N N 136 
GLU CA   C  N S 137 
GLU C    C  N N 138 
GLU O    O  N N 139 
GLU CB   C  N N 140 
GLU CG   C  N N 141 
GLU CD   C  N N 142 
GLU OE1  O  N N 143 
GLU OE2  O  N N 144 
GLU OXT  O  N N 145 
GLU H    H  N N 146 
GLU H2   H  N N 147 
GLU HA   H  N N 148 
GLU HB2  H  N N 149 
GLU HB3  H  N N 150 
GLU HG2  H  N N 151 
GLU HG3  H  N N 152 
GLU HE2  H  N N 153 
GLU HXT  H  N N 154 
GLY N    N  N N 155 
GLY CA   C  N N 156 
GLY C    C  N N 157 
GLY O    O  N N 158 
GLY OXT  O  N N 159 
GLY H    H  N N 160 
GLY H2   H  N N 161 
GLY HA2  H  N N 162 
GLY HA3  H  N N 163 
GLY HXT  H  N N 164 
GOL C1   C  N N 165 
GOL O1   O  N N 166 
GOL C2   C  N N 167 
GOL O2   O  N N 168 
GOL C3   C  N N 169 
GOL O3   O  N N 170 
GOL H11  H  N N 171 
GOL H12  H  N N 172 
GOL HO1  H  N N 173 
GOL H2   H  N N 174 
GOL HO2  H  N N 175 
GOL H31  H  N N 176 
GOL H32  H  N N 177 
GOL HO3  H  N N 178 
HIS N    N  N N 179 
HIS CA   C  N S 180 
HIS C    C  N N 181 
HIS O    O  N N 182 
HIS CB   C  N N 183 
HIS CG   C  Y N 184 
HIS ND1  N  Y N 185 
HIS CD2  C  Y N 186 
HIS CE1  C  Y N 187 
HIS NE2  N  Y N 188 
HIS OXT  O  N N 189 
HIS H    H  N N 190 
HIS H2   H  N N 191 
HIS HA   H  N N 192 
HIS HB2  H  N N 193 
HIS HB3  H  N N 194 
HIS HD1  H  N N 195 
HIS HD2  H  N N 196 
HIS HE1  H  N N 197 
HIS HE2  H  N N 198 
HIS HXT  H  N N 199 
HOH O    O  N N 200 
HOH H1   H  N N 201 
HOH H2   H  N N 202 
ILE N    N  N N 203 
ILE CA   C  N S 204 
ILE C    C  N N 205 
ILE O    O  N N 206 
ILE CB   C  N S 207 
ILE CG1  C  N N 208 
ILE CG2  C  N N 209 
ILE CD1  C  N N 210 
ILE OXT  O  N N 211 
ILE H    H  N N 212 
ILE H2   H  N N 213 
ILE HA   H  N N 214 
ILE HB   H  N N 215 
ILE HG12 H  N N 216 
ILE HG13 H  N N 217 
ILE HG21 H  N N 218 
ILE HG22 H  N N 219 
ILE HG23 H  N N 220 
ILE HD11 H  N N 221 
ILE HD12 H  N N 222 
ILE HD13 H  N N 223 
ILE HXT  H  N N 224 
LEU N    N  N N 225 
LEU CA   C  N S 226 
LEU C    C  N N 227 
LEU O    O  N N 228 
LEU CB   C  N N 229 
LEU CG   C  N N 230 
LEU CD1  C  N N 231 
LEU CD2  C  N N 232 
LEU OXT  O  N N 233 
LEU H    H  N N 234 
LEU H2   H  N N 235 
LEU HA   H  N N 236 
LEU HB2  H  N N 237 
LEU HB3  H  N N 238 
LEU HG   H  N N 239 
LEU HD11 H  N N 240 
LEU HD12 H  N N 241 
LEU HD13 H  N N 242 
LEU HD21 H  N N 243 
LEU HD22 H  N N 244 
LEU HD23 H  N N 245 
LEU HXT  H  N N 246 
LYS N    N  N N 247 
LYS CA   C  N S 248 
LYS C    C  N N 249 
LYS O    O  N N 250 
LYS CB   C  N N 251 
LYS CG   C  N N 252 
LYS CD   C  N N 253 
LYS CE   C  N N 254 
LYS NZ   N  N N 255 
LYS OXT  O  N N 256 
LYS H    H  N N 257 
LYS H2   H  N N 258 
LYS HA   H  N N 259 
LYS HB2  H  N N 260 
LYS HB3  H  N N 261 
LYS HG2  H  N N 262 
LYS HG3  H  N N 263 
LYS HD2  H  N N 264 
LYS HD3  H  N N 265 
LYS HE2  H  N N 266 
LYS HE3  H  N N 267 
LYS HZ1  H  N N 268 
LYS HZ2  H  N N 269 
LYS HZ3  H  N N 270 
LYS HXT  H  N N 271 
MET N    N  N N 272 
MET CA   C  N S 273 
MET C    C  N N 274 
MET O    O  N N 275 
MET CB   C  N N 276 
MET CG   C  N N 277 
MET SD   S  N N 278 
MET CE   C  N N 279 
MET OXT  O  N N 280 
MET H    H  N N 281 
MET H2   H  N N 282 
MET HA   H  N N 283 
MET HB2  H  N N 284 
MET HB3  H  N N 285 
MET HG2  H  N N 286 
MET HG3  H  N N 287 
MET HE1  H  N N 288 
MET HE2  H  N N 289 
MET HE3  H  N N 290 
MET HXT  H  N N 291 
NA  NA   NA N N 292 
PHE N    N  N N 293 
PHE CA   C  N S 294 
PHE C    C  N N 295 
PHE O    O  N N 296 
PHE CB   C  N N 297 
PHE CG   C  Y N 298 
PHE CD1  C  Y N 299 
PHE CD2  C  Y N 300 
PHE CE1  C  Y N 301 
PHE CE2  C  Y N 302 
PHE CZ   C  Y N 303 
PHE OXT  O  N N 304 
PHE H    H  N N 305 
PHE H2   H  N N 306 
PHE HA   H  N N 307 
PHE HB2  H  N N 308 
PHE HB3  H  N N 309 
PHE HD1  H  N N 310 
PHE HD2  H  N N 311 
PHE HE1  H  N N 312 
PHE HE2  H  N N 313 
PHE HZ   H  N N 314 
PHE HXT  H  N N 315 
PRO N    N  N N 316 
PRO CA   C  N S 317 
PRO C    C  N N 318 
PRO O    O  N N 319 
PRO CB   C  N N 320 
PRO CG   C  N N 321 
PRO CD   C  N N 322 
PRO OXT  O  N N 323 
PRO H    H  N N 324 
PRO HA   H  N N 325 
PRO HB2  H  N N 326 
PRO HB3  H  N N 327 
PRO HG2  H  N N 328 
PRO HG3  H  N N 329 
PRO HD2  H  N N 330 
PRO HD3  H  N N 331 
PRO HXT  H  N N 332 
SER N    N  N N 333 
SER CA   C  N S 334 
SER C    C  N N 335 
SER O    O  N N 336 
SER CB   C  N N 337 
SER OG   O  N N 338 
SER OXT  O  N N 339 
SER H    H  N N 340 
SER H2   H  N N 341 
SER HA   H  N N 342 
SER HB2  H  N N 343 
SER HB3  H  N N 344 
SER HG   H  N N 345 
SER HXT  H  N N 346 
SO4 S    S  N N 347 
SO4 O1   O  N N 348 
SO4 O2   O  N N 349 
SO4 O3   O  N N 350 
SO4 O4   O  N N 351 
THR N    N  N N 352 
THR CA   C  N S 353 
THR C    C  N N 354 
THR O    O  N N 355 
THR CB   C  N R 356 
THR OG1  O  N N 357 
THR CG2  C  N N 358 
THR OXT  O  N N 359 
THR H    H  N N 360 
THR H2   H  N N 361 
THR HA   H  N N 362 
THR HB   H  N N 363 
THR HG1  H  N N 364 
THR HG21 H  N N 365 
THR HG22 H  N N 366 
THR HG23 H  N N 367 
THR HXT  H  N N 368 
TRP N    N  N N 369 
TRP CA   C  N S 370 
TRP C    C  N N 371 
TRP O    O  N N 372 
TRP CB   C  N N 373 
TRP CG   C  Y N 374 
TRP CD1  C  Y N 375 
TRP CD2  C  Y N 376 
TRP NE1  N  Y N 377 
TRP CE2  C  Y N 378 
TRP CE3  C  Y N 379 
TRP CZ2  C  Y N 380 
TRP CZ3  C  Y N 381 
TRP CH2  C  Y N 382 
TRP OXT  O  N N 383 
TRP H    H  N N 384 
TRP H2   H  N N 385 
TRP HA   H  N N 386 
TRP HB2  H  N N 387 
TRP HB3  H  N N 388 
TRP HD1  H  N N 389 
TRP HE1  H  N N 390 
TRP HE3  H  N N 391 
TRP HZ2  H  N N 392 
TRP HZ3  H  N N 393 
TRP HH2  H  N N 394 
TRP HXT  H  N N 395 
TYR N    N  N N 396 
TYR CA   C  N S 397 
TYR C    C  N N 398 
TYR O    O  N N 399 
TYR CB   C  N N 400 
TYR CG   C  Y N 401 
TYR CD1  C  Y N 402 
TYR CD2  C  Y N 403 
TYR CE1  C  Y N 404 
TYR CE2  C  Y N 405 
TYR CZ   C  Y N 406 
TYR OH   O  N N 407 
TYR OXT  O  N N 408 
TYR H    H  N N 409 
TYR H2   H  N N 410 
TYR HA   H  N N 411 
TYR HB2  H  N N 412 
TYR HB3  H  N N 413 
TYR HD1  H  N N 414 
TYR HD2  H  N N 415 
TYR HE1  H  N N 416 
TYR HE2  H  N N 417 
TYR HH   H  N N 418 
TYR HXT  H  N N 419 
VAL N    N  N N 420 
VAL CA   C  N S 421 
VAL C    C  N N 422 
VAL O    O  N N 423 
VAL CB   C  N N 424 
VAL CG1  C  N N 425 
VAL CG2  C  N N 426 
VAL OXT  O  N N 427 
VAL H    H  N N 428 
VAL H2   H  N N 429 
VAL HA   H  N N 430 
VAL HB   H  N N 431 
VAL HG11 H  N N 432 
VAL HG12 H  N N 433 
VAL HG13 H  N N 434 
VAL HG21 H  N N 435 
VAL HG22 H  N N 436 
VAL HG23 H  N N 437 
VAL HXT  H  N N 438 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
6M9 C4  C5   doub Y N 1   
6M9 C4  C3   sing Y N 2   
6M9 C5  C6   sing Y N 3   
6M9 C3  C2   doub Y N 4   
6M9 C6  C1   doub Y N 5   
6M9 C6  C7   sing N N 6   
6M9 C2  C1   sing Y N 7   
6M9 C1  B1   sing N N 8   
6M9 C7  O1   sing N N 9   
6M9 B1  O1   sing N N 10  
6M9 B1  O2   sing N N 11  
6M9 C2  H1   sing N N 12  
6M9 C3  H2   sing N N 13  
6M9 C4  H3   sing N N 14  
6M9 C5  H4   sing N N 15  
6M9 C7  H5   sing N N 16  
6M9 O2  H6   sing N N 17  
6M9 C7  H7   sing N N 18  
ALA N   CA   sing N N 19  
ALA N   H    sing N N 20  
ALA N   H2   sing N N 21  
ALA CA  C    sing N N 22  
ALA CA  CB   sing N N 23  
ALA CA  HA   sing N N 24  
ALA C   O    doub N N 25  
ALA C   OXT  sing N N 26  
ALA CB  HB1  sing N N 27  
ALA CB  HB2  sing N N 28  
ALA CB  HB3  sing N N 29  
ALA OXT HXT  sing N N 30  
ARG N   CA   sing N N 31  
ARG N   H    sing N N 32  
ARG N   H2   sing N N 33  
ARG CA  C    sing N N 34  
ARG CA  CB   sing N N 35  
ARG CA  HA   sing N N 36  
ARG C   O    doub N N 37  
ARG C   OXT  sing N N 38  
ARG CB  CG   sing N N 39  
ARG CB  HB2  sing N N 40  
ARG CB  HB3  sing N N 41  
ARG CG  CD   sing N N 42  
ARG CG  HG2  sing N N 43  
ARG CG  HG3  sing N N 44  
ARG CD  NE   sing N N 45  
ARG CD  HD2  sing N N 46  
ARG CD  HD3  sing N N 47  
ARG NE  CZ   sing N N 48  
ARG NE  HE   sing N N 49  
ARG CZ  NH1  sing N N 50  
ARG CZ  NH2  doub N N 51  
ARG NH1 HH11 sing N N 52  
ARG NH1 HH12 sing N N 53  
ARG NH2 HH21 sing N N 54  
ARG NH2 HH22 sing N N 55  
ARG OXT HXT  sing N N 56  
ASN N   CA   sing N N 57  
ASN N   H    sing N N 58  
ASN N   H2   sing N N 59  
ASN CA  C    sing N N 60  
ASN CA  CB   sing N N 61  
ASN CA  HA   sing N N 62  
ASN C   O    doub N N 63  
ASN C   OXT  sing N N 64  
ASN CB  CG   sing N N 65  
ASN CB  HB2  sing N N 66  
ASN CB  HB3  sing N N 67  
ASN CG  OD1  doub N N 68  
ASN CG  ND2  sing N N 69  
ASN ND2 HD21 sing N N 70  
ASN ND2 HD22 sing N N 71  
ASN OXT HXT  sing N N 72  
ASP N   CA   sing N N 73  
ASP N   H    sing N N 74  
ASP N   H2   sing N N 75  
ASP CA  C    sing N N 76  
ASP CA  CB   sing N N 77  
ASP CA  HA   sing N N 78  
ASP C   O    doub N N 79  
ASP C   OXT  sing N N 80  
ASP CB  CG   sing N N 81  
ASP CB  HB2  sing N N 82  
ASP CB  HB3  sing N N 83  
ASP CG  OD1  doub N N 84  
ASP CG  OD2  sing N N 85  
ASP OD2 HD2  sing N N 86  
ASP OXT HXT  sing N N 87  
CYS N   CA   sing N N 88  
CYS N   H    sing N N 89  
CYS N   H2   sing N N 90  
CYS CA  C    sing N N 91  
CYS CA  CB   sing N N 92  
CYS CA  HA   sing N N 93  
CYS C   O    doub N N 94  
CYS C   OXT  sing N N 95  
CYS CB  SG   sing N N 96  
CYS CB  HB2  sing N N 97  
CYS CB  HB3  sing N N 98  
CYS SG  HG   sing N N 99  
CYS OXT HXT  sing N N 100 
DMS S   O    doub N N 101 
DMS S   C1   sing N N 102 
DMS S   C2   sing N N 103 
DMS C1  H11  sing N N 104 
DMS C1  H12  sing N N 105 
DMS C1  H13  sing N N 106 
DMS C2  H21  sing N N 107 
DMS C2  H22  sing N N 108 
DMS C2  H23  sing N N 109 
GLN N   CA   sing N N 110 
GLN N   H    sing N N 111 
GLN N   H2   sing N N 112 
GLN CA  C    sing N N 113 
GLN CA  CB   sing N N 114 
GLN CA  HA   sing N N 115 
GLN C   O    doub N N 116 
GLN C   OXT  sing N N 117 
GLN CB  CG   sing N N 118 
GLN CB  HB2  sing N N 119 
GLN CB  HB3  sing N N 120 
GLN CG  CD   sing N N 121 
GLN CG  HG2  sing N N 122 
GLN CG  HG3  sing N N 123 
GLN CD  OE1  doub N N 124 
GLN CD  NE2  sing N N 125 
GLN NE2 HE21 sing N N 126 
GLN NE2 HE22 sing N N 127 
GLN OXT HXT  sing N N 128 
GLU N   CA   sing N N 129 
GLU N   H    sing N N 130 
GLU N   H2   sing N N 131 
GLU CA  C    sing N N 132 
GLU CA  CB   sing N N 133 
GLU CA  HA   sing N N 134 
GLU C   O    doub N N 135 
GLU C   OXT  sing N N 136 
GLU CB  CG   sing N N 137 
GLU CB  HB2  sing N N 138 
GLU CB  HB3  sing N N 139 
GLU CG  CD   sing N N 140 
GLU CG  HG2  sing N N 141 
GLU CG  HG3  sing N N 142 
GLU CD  OE1  doub N N 143 
GLU CD  OE2  sing N N 144 
GLU OE2 HE2  sing N N 145 
GLU OXT HXT  sing N N 146 
GLY N   CA   sing N N 147 
GLY N   H    sing N N 148 
GLY N   H2   sing N N 149 
GLY CA  C    sing N N 150 
GLY CA  HA2  sing N N 151 
GLY CA  HA3  sing N N 152 
GLY C   O    doub N N 153 
GLY C   OXT  sing N N 154 
GLY OXT HXT  sing N N 155 
GOL C1  O1   sing N N 156 
GOL C1  C2   sing N N 157 
GOL C1  H11  sing N N 158 
GOL C1  H12  sing N N 159 
GOL O1  HO1  sing N N 160 
GOL C2  O2   sing N N 161 
GOL C2  C3   sing N N 162 
GOL C2  H2   sing N N 163 
GOL O2  HO2  sing N N 164 
GOL C3  O3   sing N N 165 
GOL C3  H31  sing N N 166 
GOL C3  H32  sing N N 167 
GOL O3  HO3  sing N N 168 
HIS N   CA   sing N N 169 
HIS N   H    sing N N 170 
HIS N   H2   sing N N 171 
HIS CA  C    sing N N 172 
HIS CA  CB   sing N N 173 
HIS CA  HA   sing N N 174 
HIS C   O    doub N N 175 
HIS C   OXT  sing N N 176 
HIS CB  CG   sing N N 177 
HIS CB  HB2  sing N N 178 
HIS CB  HB3  sing N N 179 
HIS CG  ND1  sing Y N 180 
HIS CG  CD2  doub Y N 181 
HIS ND1 CE1  doub Y N 182 
HIS ND1 HD1  sing N N 183 
HIS CD2 NE2  sing Y N 184 
HIS CD2 HD2  sing N N 185 
HIS CE1 NE2  sing Y N 186 
HIS CE1 HE1  sing N N 187 
HIS NE2 HE2  sing N N 188 
HIS OXT HXT  sing N N 189 
HOH O   H1   sing N N 190 
HOH O   H2   sing N N 191 
ILE N   CA   sing N N 192 
ILE N   H    sing N N 193 
ILE N   H2   sing N N 194 
ILE CA  C    sing N N 195 
ILE CA  CB   sing N N 196 
ILE CA  HA   sing N N 197 
ILE C   O    doub N N 198 
ILE C   OXT  sing N N 199 
ILE CB  CG1  sing N N 200 
ILE CB  CG2  sing N N 201 
ILE CB  HB   sing N N 202 
ILE CG1 CD1  sing N N 203 
ILE CG1 HG12 sing N N 204 
ILE CG1 HG13 sing N N 205 
ILE CG2 HG21 sing N N 206 
ILE CG2 HG22 sing N N 207 
ILE CG2 HG23 sing N N 208 
ILE CD1 HD11 sing N N 209 
ILE CD1 HD12 sing N N 210 
ILE CD1 HD13 sing N N 211 
ILE OXT HXT  sing N N 212 
LEU N   CA   sing N N 213 
LEU N   H    sing N N 214 
LEU N   H2   sing N N 215 
LEU CA  C    sing N N 216 
LEU CA  CB   sing N N 217 
LEU CA  HA   sing N N 218 
LEU C   O    doub N N 219 
LEU C   OXT  sing N N 220 
LEU CB  CG   sing N N 221 
LEU CB  HB2  sing N N 222 
LEU CB  HB3  sing N N 223 
LEU CG  CD1  sing N N 224 
LEU CG  CD2  sing N N 225 
LEU CG  HG   sing N N 226 
LEU CD1 HD11 sing N N 227 
LEU CD1 HD12 sing N N 228 
LEU CD1 HD13 sing N N 229 
LEU CD2 HD21 sing N N 230 
LEU CD2 HD22 sing N N 231 
LEU CD2 HD23 sing N N 232 
LEU OXT HXT  sing N N 233 
LYS N   CA   sing N N 234 
LYS N   H    sing N N 235 
LYS N   H2   sing N N 236 
LYS CA  C    sing N N 237 
LYS CA  CB   sing N N 238 
LYS CA  HA   sing N N 239 
LYS C   O    doub N N 240 
LYS C   OXT  sing N N 241 
LYS CB  CG   sing N N 242 
LYS CB  HB2  sing N N 243 
LYS CB  HB3  sing N N 244 
LYS CG  CD   sing N N 245 
LYS CG  HG2  sing N N 246 
LYS CG  HG3  sing N N 247 
LYS CD  CE   sing N N 248 
LYS CD  HD2  sing N N 249 
LYS CD  HD3  sing N N 250 
LYS CE  NZ   sing N N 251 
LYS CE  HE2  sing N N 252 
LYS CE  HE3  sing N N 253 
LYS NZ  HZ1  sing N N 254 
LYS NZ  HZ2  sing N N 255 
LYS NZ  HZ3  sing N N 256 
LYS OXT HXT  sing N N 257 
MET N   CA   sing N N 258 
MET N   H    sing N N 259 
MET N   H2   sing N N 260 
MET CA  C    sing N N 261 
MET CA  CB   sing N N 262 
MET CA  HA   sing N N 263 
MET C   O    doub N N 264 
MET C   OXT  sing N N 265 
MET CB  CG   sing N N 266 
MET CB  HB2  sing N N 267 
MET CB  HB3  sing N N 268 
MET CG  SD   sing N N 269 
MET CG  HG2  sing N N 270 
MET CG  HG3  sing N N 271 
MET SD  CE   sing N N 272 
MET CE  HE1  sing N N 273 
MET CE  HE2  sing N N 274 
MET CE  HE3  sing N N 275 
MET OXT HXT  sing N N 276 
PHE N   CA   sing N N 277 
PHE N   H    sing N N 278 
PHE N   H2   sing N N 279 
PHE CA  C    sing N N 280 
PHE CA  CB   sing N N 281 
PHE CA  HA   sing N N 282 
PHE C   O    doub N N 283 
PHE C   OXT  sing N N 284 
PHE CB  CG   sing N N 285 
PHE CB  HB2  sing N N 286 
PHE CB  HB3  sing N N 287 
PHE CG  CD1  doub Y N 288 
PHE CG  CD2  sing Y N 289 
PHE CD1 CE1  sing Y N 290 
PHE CD1 HD1  sing N N 291 
PHE CD2 CE2  doub Y N 292 
PHE CD2 HD2  sing N N 293 
PHE CE1 CZ   doub Y N 294 
PHE CE1 HE1  sing N N 295 
PHE CE2 CZ   sing Y N 296 
PHE CE2 HE2  sing N N 297 
PHE CZ  HZ   sing N N 298 
PHE OXT HXT  sing N N 299 
PRO N   CA   sing N N 300 
PRO N   CD   sing N N 301 
PRO N   H    sing N N 302 
PRO CA  C    sing N N 303 
PRO CA  CB   sing N N 304 
PRO CA  HA   sing N N 305 
PRO C   O    doub N N 306 
PRO C   OXT  sing N N 307 
PRO CB  CG   sing N N 308 
PRO CB  HB2  sing N N 309 
PRO CB  HB3  sing N N 310 
PRO CG  CD   sing N N 311 
PRO CG  HG2  sing N N 312 
PRO CG  HG3  sing N N 313 
PRO CD  HD2  sing N N 314 
PRO CD  HD3  sing N N 315 
PRO OXT HXT  sing N N 316 
SER N   CA   sing N N 317 
SER N   H    sing N N 318 
SER N   H2   sing N N 319 
SER CA  C    sing N N 320 
SER CA  CB   sing N N 321 
SER CA  HA   sing N N 322 
SER C   O    doub N N 323 
SER C   OXT  sing N N 324 
SER CB  OG   sing N N 325 
SER CB  HB2  sing N N 326 
SER CB  HB3  sing N N 327 
SER OG  HG   sing N N 328 
SER OXT HXT  sing N N 329 
SO4 S   O1   doub N N 330 
SO4 S   O2   doub N N 331 
SO4 S   O3   sing N N 332 
SO4 S   O4   sing N N 333 
THR N   CA   sing N N 334 
THR N   H    sing N N 335 
THR N   H2   sing N N 336 
THR CA  C    sing N N 337 
THR CA  CB   sing N N 338 
THR CA  HA   sing N N 339 
THR C   O    doub N N 340 
THR C   OXT  sing N N 341 
THR CB  OG1  sing N N 342 
THR CB  CG2  sing N N 343 
THR CB  HB   sing N N 344 
THR OG1 HG1  sing N N 345 
THR CG2 HG21 sing N N 346 
THR CG2 HG22 sing N N 347 
THR CG2 HG23 sing N N 348 
THR OXT HXT  sing N N 349 
TRP N   CA   sing N N 350 
TRP N   H    sing N N 351 
TRP N   H2   sing N N 352 
TRP CA  C    sing N N 353 
TRP CA  CB   sing N N 354 
TRP CA  HA   sing N N 355 
TRP C   O    doub N N 356 
TRP C   OXT  sing N N 357 
TRP CB  CG   sing N N 358 
TRP CB  HB2  sing N N 359 
TRP CB  HB3  sing N N 360 
TRP CG  CD1  doub Y N 361 
TRP CG  CD2  sing Y N 362 
TRP CD1 NE1  sing Y N 363 
TRP CD1 HD1  sing N N 364 
TRP CD2 CE2  doub Y N 365 
TRP CD2 CE3  sing Y N 366 
TRP NE1 CE2  sing Y N 367 
TRP NE1 HE1  sing N N 368 
TRP CE2 CZ2  sing Y N 369 
TRP CE3 CZ3  doub Y N 370 
TRP CE3 HE3  sing N N 371 
TRP CZ2 CH2  doub Y N 372 
TRP CZ2 HZ2  sing N N 373 
TRP CZ3 CH2  sing Y N 374 
TRP CZ3 HZ3  sing N N 375 
TRP CH2 HH2  sing N N 376 
TRP OXT HXT  sing N N 377 
TYR N   CA   sing N N 378 
TYR N   H    sing N N 379 
TYR N   H2   sing N N 380 
TYR CA  C    sing N N 381 
TYR CA  CB   sing N N 382 
TYR CA  HA   sing N N 383 
TYR C   O    doub N N 384 
TYR C   OXT  sing N N 385 
TYR CB  CG   sing N N 386 
TYR CB  HB2  sing N N 387 
TYR CB  HB3  sing N N 388 
TYR CG  CD1  doub Y N 389 
TYR CG  CD2  sing Y N 390 
TYR CD1 CE1  sing Y N 391 
TYR CD1 HD1  sing N N 392 
TYR CD2 CE2  doub Y N 393 
TYR CD2 HD2  sing N N 394 
TYR CE1 CZ   doub Y N 395 
TYR CE1 HE1  sing N N 396 
TYR CE2 CZ   sing Y N 397 
TYR CE2 HE2  sing N N 398 
TYR CZ  OH   sing N N 399 
TYR OH  HH   sing N N 400 
TYR OXT HXT  sing N N 401 
VAL N   CA   sing N N 402 
VAL N   H    sing N N 403 
VAL N   H2   sing N N 404 
VAL CA  C    sing N N 405 
VAL CA  CB   sing N N 406 
VAL CA  HA   sing N N 407 
VAL C   O    doub N N 408 
VAL C   OXT  sing N N 409 
VAL CB  CG1  sing N N 410 
VAL CB  CG2  sing N N 411 
VAL CB  HB   sing N N 412 
VAL CG1 HG11 sing N N 413 
VAL CG1 HG12 sing N N 414 
VAL CG1 HG13 sing N N 415 
VAL CG2 HG21 sing N N 416 
VAL CG2 HG22 sing N N 417 
VAL CG2 HG23 sing N N 418 
VAL OXT HXT  sing N N 419 
# 
_pdbx_audit_support.funding_organization   'Medical Research Council (MRC, United Kingdom)' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           MR/T016035/1 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6qw8 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8R2Y 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.022507 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.021810 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008556 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
B  ? ? 2.40390 1.74082 0.84097 ? 40.64930 0.64934  12.24639 ? 0.0 
;3-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
C  ? ? 3.54356 2.42580 ?       ? 25.62398 1.50364  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CL ? ? 9.50761 7.44341 ?       ? 1.04373  23.83732 ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.53795 0.34799 0.11320 ? 10.08003 29.74760 2.57510  ? 0.0 
;3-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032 2.96436 ?       ? 19.97189 1.75589  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
NA ? ? 6.63511 3.01293 1.30238 ? 5.54423  0.54580  90.85902 ? 0.0 
;3-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882 3.47563 ?       ? 15.80542 1.70748  ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732 6.39887 ?       ? 1.23737  29.19336 ?        ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . ALA A 1 5   ? 7.58700   -31.51300 5.19200  1.000 40.36324 ? 28  ALA A N    1 
ATOM   2    C  CA   . ALA A 1 5   ? 8.62000   -31.19600 4.21000  1.000 39.33561 ? 28  ALA A CA   1 
ATOM   3    C  C    . ALA A 1 5   ? 7.99500   -30.60600 2.95800  1.000 36.93352 ? 28  ALA A C    1 
ATOM   4    O  O    . ALA A 1 5   ? 8.40700   -29.54400 2.49600  1.000 36.40902 ? 28  ALA A O    1 
ATOM   5    C  CB   . ALA A 1 5   ? 9.42600   -32.43200 3.86400  1.000 40.25418 ? 28  ALA A CB   1 
ATOM   6    H  H    . ALA A 1 5   ? 7.36300   -32.34200 5.21100  1.000 48.43394 ? 28  ALA A H    1 
ATOM   7    H  HA   . ALA A 1 5   ? 9.23000   -30.54400 4.59000  1.000 47.20078 ? 28  ALA A HA   1 
ATOM   8    H  HB1  . ALA A 1 5   ? 10.12400  -32.18800 3.23600  1.000 48.30307 ? 28  ALA A HB1  1 
ATOM   9    H  HB2  . ALA A 1 5   ? 9.82100   -32.78900 4.67400  1.000 48.30307 ? 28  ALA A HB2  1 
ATOM   10   H  HB3  . ALA A 1 5   ? 8.83700   -33.09100 3.46400  1.000 48.30307 ? 28  ALA A HB3  1 
ATOM   11   N  N    . ASP A 1 6   ? 7.00100   -31.29900 2.39600  1.000 33.86233 ? 29  ASP A N    1 
ATOM   12   C  CA   . ASP A 1 6   ? 6.24700   -30.70700 1.29800  1.000 31.59675 ? 29  ASP A CA   1 
ATOM   13   C  C    . ASP A 1 6   ? 5.52800   -29.44400 1.75500  1.000 25.80933 ? 29  ASP A C    1 
ATOM   14   O  O    . ASP A 1 6   ? 5.49500   -28.44600 1.02900  1.000 24.88407 ? 29  ASP A O    1 
ATOM   15   C  CB   . ASP A 1 6   ? 5.25200   -31.71100 0.72500  1.000 35.72583 ? 29  ASP A CB   1 
ATOM   16   C  CG   . ASP A 1 6   ? 4.56500   -31.19800 -0.52800 1.000 39.81640 ? 29  ASP A CG   1 
ATOM   17   O  OD1  . ASP A 1 6   ? 5.24500   -31.03700 -1.56400 1.000 40.78504 ? 29  ASP A OD1  1 
ATOM   18   O  OD2  . ASP A 1 6   ? 3.34000   -30.95200 -0.47800 1.000 41.94507 ? 29  ASP A OD2  1 
ATOM   19   H  H    . ASP A 1 6   ? 6.75400   -32.08900 2.62700  1.000 40.63284 ? 29  ASP A H    1 
ATOM   20   H  HA   . ASP A 1 6   ? 6.86500   -30.47100 0.58800  1.000 37.91415 ? 29  ASP A HA   1 
ATOM   21   H  HB2  . ASP A 1 6   ? 5.72200   -32.52900 0.49800  1.000 42.86904 ? 29  ASP A HB2  1 
ATOM   22   H  HB3  . ASP A 1 6   ? 4.56900   -31.89500 1.38900  1.000 42.86904 ? 29  ASP A HB3  1 
ATOM   23   N  N    A VAL A 1 7   ? 4.94900   -29.46300 2.95700  0.287 24.15421 ? 30  VAL A N    1 
ATOM   24   N  N    B VAL A 1 7   ? 4.93600   -29.46800 2.95100  0.713 23.37280 ? 30  VAL A N    1 
ATOM   25   C  CA   A VAL A 1 7   ? 4.29000   -28.26200 3.46600  0.287 22.42147 ? 30  VAL A CA   1 
ATOM   26   C  CA   B VAL A 1 7   ? 4.29200   -28.26500 3.47100  0.713 21.49499 ? 30  VAL A CA   1 
ATOM   27   C  C    A VAL A 1 7   ? 5.30500   -27.14000 3.64300  0.287 21.75703 ? 30  VAL A C    1 
ATOM   28   C  C    B VAL A 1 7   ? 5.31300   -27.14600 3.61800  0.713 20.21635 ? 30  VAL A C    1 
ATOM   29   O  O    A VAL A 1 7   ? 5.01400   -25.96900 3.37100  0.287 21.31690 ? 30  VAL A O    1 
ATOM   30   O  O    B VAL A 1 7   ? 5.03300   -25.98300 3.31000  0.713 18.60608 ? 30  VAL A O    1 
ATOM   31   C  CB   A VAL A 1 7   ? 3.52500   -28.56900 4.76900  0.287 21.73921 ? 30  VAL A CB   1 
ATOM   32   C  CB   B VAL A 1 7   ? 3.57100   -28.55700 4.80100  0.713 22.22416 ? 30  VAL A CB   1 
ATOM   33   C  CG1  A VAL A 1 7   ? 4.48100   -28.97300 5.88600  0.287 21.27611 ? 30  VAL A CG1  1 
ATOM   34   C  CG1  B VAL A 1 7   ? 3.05100   -27.26700 5.41300  0.713 22.70611 ? 30  VAL A CG1  1 
ATOM   35   C  CG2  A VAL A 1 7   ? 2.68300   -27.37000 5.18200  0.287 21.73068 ? 30  VAL A CG2  1 
ATOM   36   C  CG2  B VAL A 1 7   ? 2.42800   -29.53300 4.58400  0.713 23.31134 ? 30  VAL A CG2  1 
ATOM   37   H  H    A VAL A 1 7   ? 4.92400   -30.14200 3.48400  0.287 28.98310 ? 30  VAL A H    1 
ATOM   38   H  H    B VAL A 1 7   ? 4.89500   -30.15400 3.46900  0.713 28.04541 ? 30  VAL A H    1 
ATOM   39   H  HA   A VAL A 1 7   ? 3.63600   -27.96900 2.81400  0.287 26.90382 ? 30  VAL A HA   1 
ATOM   40   H  HA   B VAL A 1 7   ? 3.61900   -27.97900 2.83400  0.713 25.79203 ? 30  VAL A HA   1 
ATOM   41   H  HB   A VAL A 1 7   ? 2.93000   -29.31900 4.60900  0.287 26.08510 ? 30  VAL A HB   1 
ATOM   42   H  HB   B VAL A 1 7   ? 4.20200   -28.96000 5.41700  0.713 26.66704 ? 30  VAL A HB   1 
ATOM   43   H  HG11 A VAL A 1 7   ? 3.96700   -29.19400 6.67800  0.287 25.52939 ? 30  VAL A HG11 1 
ATOM   44   H  HG11 B VAL A 1 7   ? 2.40100   -27.48300 6.10000  0.713 27.24538 ? 30  VAL A HG11 1 
ATOM   45   H  HG12 A VAL A 1 7   ? 4.99500   -29.74300 5.59900  0.287 25.52939 ? 30  VAL A HG12 1 
ATOM   46   H  HG12 B VAL A 1 7   ? 3.79400   -26.78000 5.80200  0.713 27.24538 ? 30  VAL A HG12 1 
ATOM   47   H  HG13 A VAL A 1 7   ? 5.07600   -28.23000 6.07600  0.287 25.52939 ? 30  VAL A HG13 1 
ATOM   48   H  HG13 B VAL A 1 7   ? 2.63300   -26.73400 4.71800  0.713 27.24538 ? 30  VAL A HG13 1 
ATOM   49   H  HG21 A VAL A 1 7   ? 2.16400   -27.60500 5.96700  0.287 26.07487 ? 30  VAL A HG21 1 
ATOM   50   H  HG21 B VAL A 1 7   ? 2.04600   -29.76800 5.44400  0.713 27.97166 ? 30  VAL A HG21 1 
ATOM   51   H  HG22 A VAL A 1 7   ? 3.27200   -26.62600 5.38500  0.287 26.07487 ? 30  VAL A HG22 1 
ATOM   52   H  HG22 B VAL A 1 7   ? 1.75500   -29.11200 4.02700  0.713 27.97166 ? 30  VAL A HG22 1 
ATOM   53   H  HG23 A VAL A 1 7   ? 2.09000   -27.13400 4.45200  0.287 26.07487 ? 30  VAL A HG23 1 
ATOM   54   H  HG23 B VAL A 1 7   ? 2.77100   -30.32800 4.14500  0.713 27.97166 ? 30  VAL A HG23 1 
ATOM   55   N  N    . GLN A 1 8   ? 6.51500   -27.48100 4.09300  1.000 21.80528 ? 31  GLN A N    1 
ATOM   56   C  CA   . GLN A 1 8   ? 7.55500   -26.47100 4.25200  1.000 21.99182 ? 31  GLN A CA   1 
ATOM   57   C  C    . GLN A 1 8   ? 7.97900   -25.90100 2.91000  1.000 21.45505 ? 31  GLN A C    1 
ATOM   58   O  O    . GLN A 1 8   ? 8.18200   -24.68800 2.77700  1.000 21.38271 ? 31  GLN A O    1 
ATOM   59   C  CB   . GLN A 1 8   ? 8.75500   -27.08600 4.96900  1.000 22.76920 ? 31  GLN A CB   1 
ATOM   60   C  CG   . GLN A 1 8   ? 8.47100   -27.40900 6.41400  1.000 23.11672 ? 31  GLN A CG   1 
ATOM   61   C  CD   . GLN A 1 8   ? 8.27700   -26.15800 7.25200  1.000 23.47996 ? 31  GLN A CD   1 
ATOM   62   O  OE1  . GLN A 1 8   ? 8.91000   -25.12600 7.00700  1.000 24.24019 ? 31  GLN A OE1  1 
ATOM   63   N  NE2  . GLN A 1 8   ? 7.40200   -26.24100 8.24200  1.000 23.51732 ? 31  GLN A NE2  1 
ATOM   64   H  H    A GLN A 1 8   ? 6.75300   -28.27800 4.30900  0.287 26.16439 ? 31  GLN A H    1 
ATOM   65   H  H    B GLN A 1 8   ? 6.74800   -28.27500 4.32700  0.713 26.16439 ? 31  GLN A H    1 
ATOM   66   H  HA   . GLN A 1 8   ? 7.21100   -25.74300 4.79300  1.000 26.38823 ? 31  GLN A HA   1 
ATOM   67   H  HB2  . GLN A 1 8   ? 9.00200   -27.91000 4.52000  1.000 27.32109 ? 31  GLN A HB2  1 
ATOM   68   H  HB3  . GLN A 1 8   ? 9.49400   -26.45800 4.94100  1.000 27.32109 ? 31  GLN A HB3  1 
ATOM   69   H  HG2  . GLN A 1 8   ? 7.66100   -27.93900 6.46900  1.000 27.73811 ? 31  GLN A HG2  1 
ATOM   70   H  HG3  . GLN A 1 8   ? 9.21800   -27.90600 6.78200  1.000 27.73811 ? 31  GLN A HG3  1 
ATOM   71   H  HE21 . GLN A 1 8   ? 6.97900   -26.97700 8.38200  1.000 28.21884 ? 31  GLN A HE21 1 
ATOM   72   H  HE22 . GLN A 1 8   ? 7.25600   -25.55900 8.74500  1.000 28.21884 ? 31  GLN A HE22 1 
ATOM   73   N  N    . GLN A 1 9   ? 8.13000   -26.75400 1.90100  1.000 22.72157 ? 32  GLN A N    1 
ATOM   74   C  CA   . GLN A 1 9   ? 8.47700   -26.24800 0.58200  1.000 24.22228 ? 32  GLN A CA   1 
ATOM   75   C  C    . GLN A 1 9   ? 7.38200   -25.33600 0.04300  1.000 21.16615 ? 32  GLN A C    1 
ATOM   76   O  O    . GLN A 1 9   ? 7.66800   -24.29400 -0.55300 1.000 20.71391 ? 32  GLN A O    1 
ATOM   77   C  CB   . GLN A 1 9   ? 8.73100   -27.42000 -0.36100 1.000 29.59857 ? 32  GLN A CB   1 
ATOM   78   C  CG   . GLN A 1 9   ? 9.20700   -27.01200 -1.73500 1.000 35.43019 ? 32  GLN A CG   1 
ATOM   79   C  CD   . GLN A 1 9   ? 9.82900   -28.17100 -2.49000 1.000 40.48673 ? 32  GLN A CD   1 
ATOM   80   O  OE1  . GLN A 1 9   ? 10.12000  -29.21800 -1.90800 1.000 42.52741 ? 32  GLN A OE1  1 
ATOM   81   N  NE2  . GLN A 1 9   ? 10.03400  -27.99200 -3.78800 1.000 42.40211 ? 32  GLN A NE2  1 
ATOM   82   H  H    . GLN A 1 9   ? 8.04000   -27.60800 1.95300  1.000 27.26394 ? 32  GLN A H    1 
ATOM   83   H  HA   . GLN A 1 9   ? 9.29300   -25.72600 0.63700  1.000 29.06479 ? 32  GLN A HA   1 
ATOM   84   H  HB2  . GLN A 1 9   ? 9.41100   -27.99100 0.02900  1.000 35.51634 ? 32  GLN A HB2  1 
ATOM   85   H  HB3  . GLN A 1 9   ? 7.90400   -27.91600 -0.47100 1.000 35.51634 ? 32  GLN A HB3  1 
ATOM   86   H  HG2  . GLN A 1 9   ? 8.45300   -26.68400 -2.24900 1.000 42.51428 ? 32  GLN A HG2  1 
ATOM   87   H  HG3  . GLN A 1 9   ? 9.87600   -26.31500 -1.64600 1.000 42.51428 ? 32  GLN A HG3  1 
ATOM   88   H  HE21 . GLN A 1 9   ? 9.81700   -27.24700 -4.15900 1.000 50.88058 ? 32  GLN A HE21 1 
ATOM   89   H  HE22 . GLN A 1 9   ? 10.38400  -28.62100 -4.25900 1.000 50.88058 ? 32  GLN A HE22 1 
ATOM   90   N  N    . LYS A 1 10  ? 6.11900   -25.70400 0.25100  1.000 19.13607 ? 33  LYS A N    1 
ATOM   91   C  CA   . LYS A 1 10  ? 5.02900   -24.86800 -0.23900 1.000 17.99964 ? 33  LYS A CA   1 
ATOM   92   C  C    . LYS A 1 10  ? 4.98700   -23.52400 0.48600  1.000 16.44552 ? 33  LYS A C    1 
ATOM   93   O  O    . LYS A 1 10  ? 4.73100   -22.49100 -0.14100 1.000 16.28061 ? 33  LYS A O    1 
ATOM   94   C  CB   . LYS A 1 10  ? 3.69700   -25.61200 -0.11900 1.000 19.44536 ? 33  LYS A CB   1 
ATOM   95   C  CG   . LYS A 1 10  ? 3.46700   -26.71700 -1.17200 1.000 23.24058 ? 33  LYS A CG   1 
ATOM   96   C  CD   . LYS A 1 10  ? 2.17100   -27.46100 -0.87200 1.000 27.89652 ? 33  LYS A CD   1 
ATOM   97   C  CE   . LYS A 1 10  ? 1.57300   -28.16700 -2.08200 1.000 32.12628 ? 33  LYS A CE   1 
ATOM   98   N  NZ   . LYS A 1 10  ? 2.26000   -29.43000 -2.43800 1.000 34.98532 ? 33  LYS A NZ   1 
ATOM   99   H  H    . LYS A 1 10  ? 5.87200   -26.41700 0.66300  1.000 22.96133 ? 33  LYS A H    1 
ATOM   100  H  HA   . LYS A 1 10  ? 5.17400   -24.68300 -1.18000 1.000 21.59762 ? 33  LYS A HA   1 
ATOM   101  H  HB2  . LYS A 1 10  ? 3.65800   -26.03100 0.75500  1.000 23.33249 ? 33  LYS A HB2  1 
ATOM   102  H  HB3  . LYS A 1 10  ? 2.97700   -24.96900 -0.21100 1.000 23.33249 ? 33  LYS A HB3  1 
ATOM   103  H  HG2  . LYS A 1 10  ? 3.40100   -26.31900 -2.05400 1.000 27.88675 ? 33  LYS A HG2  1 
ATOM   104  H  HG3  . LYS A 1 10  ? 4.20200   -27.35000 -1.14800 1.000 27.88675 ? 33  LYS A HG3  1 
ATOM   105  H  HD2  . LYS A 1 10  ? 2.34600   -28.13300 -0.19500 1.000 33.47388 ? 33  LYS A HD2  1 
ATOM   106  H  HD3  . LYS A 1 10  ? 1.51400   -26.82600 -0.54700 1.000 33.47388 ? 33  LYS A HD3  1 
ATOM   107  H  HE2  . LYS A 1 10  ? 0.64500   -28.37900 -1.89300 1.000 38.54958 ? 33  LYS A HE2  1 
ATOM   108  H  HE3  . LYS A 1 10  ? 1.62800   -27.57500 -2.84800 1.000 38.54958 ? 33  LYS A HE3  1 
ATOM   109  H  HZ1  . LYS A 1 10  ? 2.14300   -30.03200 -1.79200 1.000 41.98043 ? 33  LYS A HZ1  1 
ATOM   110  H  HZ2  . LYS A 1 10  ? 1.92800   -29.75300 -3.19800 1.000 41.98043 ? 33  LYS A HZ2  1 
ATOM   111  H  HZ3  . LYS A 1 10  ? 3.13100   -29.28300 -2.54200 1.000 41.98043 ? 33  LYS A HZ3  1 
ATOM   112  N  N    . LEU A 1 11  ? 5.22600   -23.50200 1.80500  1.000 15.81587 ? 34  LEU A N    1 
ATOM   113  C  CA   . LEU A 1 11  ? 5.23500   -22.21700 2.50000  1.000 15.43278 ? 34  LEU A CA   1 
ATOM   114  C  C    . LEU A 1 11  ? 6.40500   -21.35200 2.04500  1.000 15.33459 ? 34  LEU A C    1 
ATOM   115  O  O    . LEU A 1 11  ? 6.26100   -20.13500 1.89400  1.000 15.64908 ? 34  LEU A O    1 
ATOM   116  C  CB   . LEU A 1 11  ? 5.27500   -22.42300 4.01100  1.000 14.93089 ? 34  LEU A CB   1 
ATOM   117  C  CG   . LEU A 1 11  ? 3.98500   -22.98500 4.60200  1.000 15.16116 ? 34  LEU A CG   1 
ATOM   118  C  CD1  . LEU A 1 11  ? 4.19700   -23.28400 6.08100  1.000 15.64983 ? 34  LEU A CD1  1 
ATOM   119  C  CD2  . LEU A 1 11  ? 2.81400   -22.03900 4.42400  1.000 14.79916 ? 34  LEU A CD2  1 
ATOM   120  H  H    . LEU A 1 11  ? 5.37800   -24.19000 2.29700  1.000 18.97709 ? 34  LEU A H    1 
ATOM   121  H  HA   . LEU A 1 11  ? 4.41200   -21.74900 2.28900  1.000 18.51739 ? 34  LEU A HA   1 
ATOM   122  H  HB2  . LEU A 1 11  ? 5.98900   -23.04500 4.22000  1.000 17.91512 ? 34  LEU A HB2  1 
ATOM   123  H  HB3  . LEU A 1 11  ? 5.44500   -21.56800 4.43500  1.000 17.91512 ? 34  LEU A HB3  1 
ATOM   124  H  HG   . LEU A 1 11  ? 3.76000   -23.80200 4.13100  1.000 18.19145 ? 34  LEU A HG   1 
ATOM   125  H  HD11 . LEU A 1 11  ? 3.36600   -23.61200 6.45900  1.000 18.77785 ? 34  LEU A HD11 1 
ATOM   126  H  HD12 . LEU A 1 11  ? 4.89000   -23.95700 6.17000  1.000 18.77785 ? 34  LEU A HD12 1 
ATOM   127  H  HD13 . LEU A 1 11  ? 4.46800   -22.46900 6.53200  1.000 18.77785 ? 34  LEU A HD13 1 
ATOM   128  H  HD21 . LEU A 1 11  ? 2.07100   -22.35000 4.96500  1.000 17.75705 ? 34  LEU A HD21 1 
ATOM   129  H  HD22 . LEU A 1 11  ? 3.08000   -21.15000 4.70800  1.000 17.75705 ? 34  LEU A HD22 1 
ATOM   130  H  HD23 . LEU A 1 11  ? 2.55900   -22.02500 3.48800  1.000 17.75705 ? 34  LEU A HD23 1 
ATOM   131  N  N    . ALA A 1 12  ? 7.57300   -21.96000 1.82800  1.000 16.64803 ? 35  ALA A N    1 
ATOM   132  C  CA   . ALA A 1 12  ? 8.70700   -21.18500 1.34600  1.000 17.63753 ? 35  ALA A CA   1 
ATOM   133  C  C    . ALA A 1 12  ? 8.42300   -20.61500 -0.03700 1.000 17.15934 ? 35  ALA A C    1 
ATOM   134  O  O    . ALA A 1 12  ? 8.79600   -19.47400 -0.33800 1.000 17.35559 ? 35  ALA A O    1 
ATOM   135  C  CB   . ALA A 1 12  ? 9.95100   -22.07000 1.30000  1.000 17.84919 ? 35  ALA A CB   1 
ATOM   136  H  H    . ALA A 1 12  ? 7.72800   -22.79700 1.95000  1.000 19.97568 ? 35  ALA A H    1 
ATOM   137  H  HA   . ALA A 1 12  ? 8.87300   -20.44900 1.95600  1.000 21.16309 ? 35  ALA A HA   1 
ATOM   138  H  HB1  . ALA A 1 12  ? 10.69800  -21.54800 0.97000  1.000 21.41708 ? 35  ALA A HB1  1 
ATOM   139  H  HB2  . ALA A 1 12  ? 10.14200  -22.39200 2.19500  1.000 21.41708 ? 35  ALA A HB2  1 
ATOM   140  H  HB3  . ALA A 1 12  ? 9.78300   -22.82000 0.70800  1.000 21.41708 ? 35  ALA A HB3  1 
ATOM   141  N  N    . GLU A 1 13  ? 7.78600   -21.40800 -0.90300 1.000 17.25917 ? 36  GLU A N    1 
ATOM   142  C  CA   . GLU A 1 13  ? 7.43400   -20.92000 -2.23300 1.000 18.83776 ? 36  GLU A CA   1 
ATOM   143  C  C    . GLU A 1 13  ? 6.43000   -19.77700 -2.14900 1.000 17.45981 ? 36  GLU A C    1 
ATOM   144  O  O    . GLU A 1 13  ? 6.55200   -18.77600 -2.87000 1.000 17.23042 ? 36  GLU A O    1 
ATOM   145  C  CB   . GLU A 1 13  ? 6.88600   -22.07500 -3.08100 1.000 22.77804 ? 36  GLU A CB   1 
ATOM   146  C  CG   . GLU A 1 13  ? 7.94100   -23.12000 -3.45400 1.000 28.54177 ? 36  GLU A CG   1 
ATOM   147  C  CD   . GLU A 1 13  ? 7.35900   -24.39000 -4.07100 1.000 33.50732 ? 36  GLU A CD   1 
ATOM   148  O  OE1  . GLU A 1 13  ? 6.11900   -24.56800 -4.05900 1.000 35.80768 ? 36  GLU A OE1  1 
ATOM   149  O  OE2  . GLU A 1 13  ? 8.15300   -25.21800 -4.57000 1.000 35.61846 ? 36  GLU A OE2  1 
ATOM   150  H  H    . GLU A 1 13  ? 7.55200   -22.22000 -0.74500 1.000 20.70906 ? 36  GLU A H    1 
ATOM   151  H  HA   . GLU A 1 13  ? 8.23000   -20.58200 -2.67300 1.000 22.60336 ? 36  GLU A HA   1 
ATOM   152  H  HB2  . GLU A 1 13  ? 6.18700   -22.52400 -2.58100 1.000 27.33170 ? 36  GLU A HB2  1 
ATOM   153  H  HB3  . GLU A 1 13  ? 6.52400   -21.71200 -3.90500 1.000 27.33170 ? 36  GLU A HB3  1 
ATOM   154  H  HG2  . GLU A 1 13  ? 8.55200   -22.73000 -4.09900 1.000 34.24818 ? 36  GLU A HG2  1 
ATOM   155  H  HG3  . GLU A 1 13  ? 8.42400   -23.37500 -2.65200 1.000 34.24818 ? 36  GLU A HG3  1 
ATOM   156  N  N    . LEU A 1 14  ? 5.43300   -19.90500 -1.27000 1.000 16.35594 ? 37  LEU A N    1 
ATOM   157  C  CA   . LEU A 1 14  ? 4.47000   -18.82600 -1.07700 1.000 15.64851 ? 37  LEU A CA   1 
ATOM   158  C  C    . LEU A 1 14  ? 5.17900   -17.56200 -0.61200 1.000 15.48129 ? 37  LEU A C    1 
ATOM   159  O  O    . LEU A 1 14  ? 4.93500   -16.46400 -1.12800 1.000 15.52391 ? 37  LEU A O    1 
ATOM   160  C  CB   . LEU A 1 14  ? 3.42600   -19.25000 -0.04200 1.000 14.66371 ? 37  LEU A CB   1 
ATOM   161  C  CG   . LEU A 1 14  ? 2.46600   -18.15400 0.41700  1.000 14.31676 ? 37  LEU A CG   1 
ATOM   162  C  CD1  . LEU A 1 14  ? 1.67500   -17.57100 -0.75100 1.000 15.17807 ? 37  LEU A CD1  1 
ATOM   163  C  CD2  . LEU A 1 14  ? 1.53600   -18.71900 1.47000  1.000 14.05323 ? 37  LEU A CD2  1 
ATOM   164  H  H    . LEU A 1 14  ? 5.29500   -20.59800 -0.78100 1.000 19.62517 ? 37  LEU A H    1 
ATOM   165  H  HA   . LEU A 1 14  ? 4.01900   -18.64300 -1.91600 1.000 18.77626 ? 37  LEU A HA   1 
ATOM   166  H  HB2  . LEU A 1 14  ? 2.88900   -19.96100 -0.42600 1.000 17.59450 ? 37  LEU A HB2  1 
ATOM   167  H  HB3  . LEU A 1 14  ? 3.89200   -19.57400 0.74500  1.000 17.59450 ? 37  LEU A HB3  1 
ATOM   168  H  HG   . LEU A 1 14  ? 2.97500   -17.42200 0.79900  1.000 17.17816 ? 37  LEU A HG   1 
ATOM   169  H  HD11 . LEU A 1 14  ? 1.00500   -16.96100 -0.40600 1.000 18.21173 ? 37  LEU A HD11 1 
ATOM   170  H  HD12 . LEU A 1 14  ? 2.28300   -17.09700 -1.33900 1.000 18.21173 ? 37  LEU A HD12 1 
ATOM   171  H  HD13 . LEU A 1 14  ? 1.24500   -18.29500 -1.23300 1.000 18.21173 ? 37  LEU A HD13 1 
ATOM   172  H  HD21 . LEU A 1 14  ? 0.90500   -18.03200 1.73600  1.000 16.86192 ? 37  LEU A HD21 1 
ATOM   173  H  HD22 . LEU A 1 14  ? 1.06000   -19.47800 1.09700  1.000 16.86192 ? 37  LEU A HD22 1 
ATOM   174  H  HD23 . LEU A 1 14  ? 2.05900   -19.00100 2.23600  1.000 16.86192 ? 37  LEU A HD23 1 
ATOM   175  N  N    . GLU A 1 15  ? 6.06700   -17.69600 0.36900  1.000 15.25560 ? 38  GLU A N    1 
ATOM   176  C  CA   . GLU A 1 15  ? 6.77000   -16.52500 0.87000  1.000 15.35335 ? 38  GLU A CA   1 
ATOM   177  C  C    . GLU A 1 15  ? 7.57400   -15.87000 -0.24200 1.000 16.30074 ? 38  GLU A C    1 
ATOM   178  O  O    . GLU A 1 15  ? 7.53000   -14.64700 -0.41500 1.000 15.64763 ? 38  GLU A O    1 
ATOM   179  C  CB   . GLU A 1 15  ? 7.66900   -16.89900 2.04500  1.000 14.55486 ? 38  GLU A CB   1 
ATOM   180  C  CG   . GLU A 1 15  ? 8.43000   -15.70600 2.58300  1.000 14.29906 ? 38  GLU A CG   1 
ATOM   181  C  CD   . GLU A 1 15  ? 9.32700   -16.06100 3.73100  1.000 13.87622 ? 38  GLU A CD   1 
ATOM   182  O  OE1  . GLU A 1 15  ? 10.25900  -16.87300 3.53300  1.000 14.99713 ? 38  GLU A OE1  1 
ATOM   183  O  OE2  . GLU A 1 15  ? 9.09600   -15.53600 4.83100  1.000 13.57362 ? 38  GLU A OE2  1 
ATOM   184  H  H    . GLU A 1 15  ? 6.27500   -18.43800 0.75200  1.000 18.30477 ? 38  GLU A H    1 
ATOM   185  H  HA   . GLU A 1 15  ? 6.11900   -15.88400 1.19700  1.000 18.42207 ? 38  GLU A HA   1 
ATOM   186  H  HB2  . GLU A 1 15  ? 7.12300   -17.25900 2.76100  1.000 17.46388 ? 38  GLU A HB2  1 
ATOM   187  H  HB3  . GLU A 1 15  ? 8.31300   -17.56300 1.75300  1.000 17.46388 ? 38  GLU A HB3  1 
ATOM   188  H  HG2  . GLU A 1 15  ? 8.98100   -15.33600 1.87600  1.000 17.15693 ? 38  GLU A HG2  1 
ATOM   189  H  HG3  . GLU A 1 15  ? 7.79700   -15.04000 2.89200  1.000 17.15693 ? 38  GLU A HG3  1 
ATOM   190  N  N    . ARG A 1 16  ? 8.30100   -16.67300 -1.02000 1.000 18.15717 ? 39  ARG A N    1 
ATOM   191  C  CA   . ARG A 1 16  ? 9.09600   -16.10800 -2.10000 1.000 19.00915 ? 39  ARG A CA   1 
ATOM   192  C  C    . ARG A 1 16  ? 8.21500   -15.34300 -3.07900 1.000 18.03806 ? 39  ARG A C    1 
ATOM   193  O  O    . ARG A 1 16  ? 8.52800   -14.21000 -3.45400 1.000 18.37746 ? 39  ARG A O    1 
ATOM   194  C  CB   . ARG A 1 16  ? 9.87100   -17.21700 -2.81200 1.000 21.80732 ? 39  ARG A CB   1 
ATOM   195  C  CG   . ARG A 1 16  ? 10.76800  -16.70500 -3.91900 1.000 26.22922 ? 39  ARG A CG   1 
ATOM   196  C  CD   . ARG A 1 16  ? 11.65500  -17.79900 -4.47200 1.000 31.33364 ? 39  ARG A CD   1 
ATOM   197  N  NE   . ARG A 1 16  ? 10.90200  -18.80000 -5.21900 1.000 35.79507 ? 39  ARG A NE   1 
ATOM   198  C  CZ   . ARG A 1 16  ? 10.64500  -20.03300 -4.80000 1.000 38.81376 ? 39  ARG A CZ   1 
ATOM   199  N  NH1  . ARG A 1 16  ? 11.04100  -20.46000 -3.60900 1.000 39.92930 ? 39  ARG A NH1  1 
ATOM   200  N  NH2  . ARG A 1 16  ? 9.97400   -20.85800 -5.59800 1.000 40.14379 ? 39  ARG A NH2  1 
ATOM   201  H  H    . ARG A 1 16  ? 8.34700   -17.52800 -0.94300 1.000 21.78665 ? 39  ARG A H    1 
ATOM   202  H  HA   . ARG A 1 16  ? 9.74200   -15.48700 -1.72800 1.000 22.80903 ? 39  ARG A HA   1 
ATOM   203  H  HB2  . ARG A 1 16  ? 10.42900  -17.67600 -2.16400 1.000 26.16683 ? 39  ARG A HB2  1 
ATOM   204  H  HB3  . ARG A 1 16  ? 9.23900   -17.83900 -3.20400 1.000 26.16683 ? 39  ARG A HB3  1 
ATOM   205  H  HG2  . ARG A 1 16  ? 10.22000  -16.36400 -4.64300 1.000 31.47312 ? 39  ARG A HG2  1 
ATOM   206  H  HG3  . ARG A 1 16  ? 11.33600  -16.00000 -3.57100 1.000 31.47312 ? 39  ARG A HG3  1 
ATOM   207  H  HD2  . ARG A 1 16  ? 12.31000  -17.40600 -5.07000 1.000 37.59842 ? 39  ARG A HD2  1 
ATOM   208  H  HD3  . ARG A 1 16  ? 12.10400  -18.24600 -3.73700 1.000 37.59842 ? 39  ARG A HD3  1 
ATOM   209  H  HE   . ARG A 1 16  ? 10.60100  -18.57400 -5.99200 1.000 42.95213 ? 39  ARG A HE   1 
ATOM   210  H  HH11 . ARG A 1 16  ? 11.47600  -19.93300 -3.08600 1.000 47.91321 ? 39  ARG A HH11 1 
ATOM   211  H  HH12 . ARG A 1 16  ? 10.86300  -21.26300 -3.35900 1.000 47.91321 ? 39  ARG A HH12 1 
ATOM   212  H  HH21 . ARG A 1 16  ? 9.71300   -20.59000 -6.37200 1.000 48.17060 ? 39  ARG A HH21 1 
ATOM   213  H  HH22 . ARG A 1 16  ? 9.80000   -21.66000 -5.33900 1.000 48.17060 ? 39  ARG A HH22 1 
ATOM   214  N  N    A GLN A 1 17  ? 7.09600   -15.94400 -3.49200 0.516 17.55655 ? 40  GLN A N    1 
ATOM   215  N  N    B GLN A 1 17  ? 7.10600   -15.95200 -3.50400 0.484 17.77487 ? 40  GLN A N    1 
ATOM   216  C  CA   A GLN A 1 17  ? 6.22300   -15.28200 -4.45600 0.516 17.87789 ? 40  GLN A CA   1 
ATOM   217  C  CA   B GLN A 1 17  ? 6.21400   -15.28400 -4.44400 0.484 18.34869 ? 40  GLN A CA   1 
ATOM   218  C  C    A GLN A 1 17  ? 5.62600   -14.00400 -3.88500 0.516 16.55216 ? 40  GLN A C    1 
ATOM   219  C  C    B GLN A 1 17  ? 5.69100   -13.97800 -3.86900 0.484 16.72270 ? 40  GLN A C    1 
ATOM   220  O  O    A GLN A 1 17  ? 5.41000   -13.03400 -4.62300 0.516 16.99533 ? 40  GLN A O    1 
ATOM   221  O  O    B GLN A 1 17  ? 5.57900   -12.97300 -4.58100 0.484 16.66543 ? 40  GLN A O    1 
ATOM   222  C  CB   A GLN A 1 17  ? 5.11200   -16.23100 -4.91000 0.516 20.56287 ? 40  GLN A CB   1 
ATOM   223  C  CB   B GLN A 1 17  ? 5.04000   -16.20000 -4.78100 0.484 21.11568 ? 40  GLN A CB   1 
ATOM   224  C  CG   A GLN A 1 17  ? 4.25000   -15.66200 -6.03200 0.516 23.57744 ? 40  GLN A CG   1 
ATOM   225  C  CG   B GLN A 1 17  ? 5.42200   -17.45900 -5.51800 0.484 24.20165 ? 40  GLN A CG   1 
ATOM   226  C  CD   A GLN A 1 17  ? 3.18800   -16.63400 -6.52000 0.516 27.51994 ? 40  GLN A CD   1 
ATOM   227  C  CD   B GLN A 1 17  ? 4.28400   -18.46200 -5.56300 0.484 27.27547 ? 40  GLN A CD   1 
ATOM   228  O  OE1  A GLN A 1 17  ? 3.09700   -17.76200 -6.03600 0.516 30.08431 ? 40  GLN A OE1  1 
ATOM   229  O  OE1  B GLN A 1 17  ? 3.47200   -18.53900 -4.63900 0.484 28.23723 ? 40  GLN A OE1  1 
ATOM   230  N  NE2  A GLN A 1 17  ? 2.37100   -16.19400 -7.47200 0.516 28.77302 ? 40  GLN A NE2  1 
ATOM   231  N  NE2  B GLN A 1 17  ? 4.21400   -19.22800 -6.64200 0.484 28.64500 ? 40  GLN A NE2  1 
ATOM   232  H  H    A GLN A 1 17  ? 6.82600   -16.71900 -3.23400 0.516 21.06592 ? 40  GLN A H    1 
ATOM   233  H  H    B GLN A 1 17  ? 6.85300   -16.73900 -3.26600 0.484 21.32789 ? 40  GLN A H    1 
ATOM   234  H  HA   A GLN A 1 17  ? 6.74900   -15.04800 -5.23600 0.516 21.45152 ? 40  GLN A HA   1 
ATOM   235  H  HA   B GLN A 1 17  ? 6.70600   -15.09100 -5.25700 0.484 22.01648 ? 40  GLN A HA   1 
ATOM   236  H  HB2  A GLN A 1 17  ? 5.51400   -17.05300 -5.23100 0.516 24.67349 ? 40  GLN A HB2  1 
ATOM   237  H  HB2  B GLN A 1 17  ? 4.60700   -16.46400 -3.95400 0.484 25.33687 ? 40  GLN A HB2  1 
ATOM   238  H  HB3  A GLN A 1 17  ? 4.53200   -16.41700 -4.15500 0.516 24.67349 ? 40  GLN A HB3  1 
ATOM   239  H  HB3  B GLN A 1 17  ? 4.41700   -15.71000 -5.34000 0.484 25.33687 ? 40  GLN A HB3  1 
ATOM   240  H  HG2  A GLN A 1 17  ? 3.80000   -14.86500 -5.71000 0.516 28.29097 ? 40  GLN A HG2  1 
ATOM   241  H  HG2  B GLN A 1 17  ? 5.66300   -17.23400 -6.43000 0.484 29.04003 ? 40  GLN A HG2  1 
ATOM   242  H  HG3  A GLN A 1 17  ? 4.82000   -15.44000 -6.78500 0.516 28.29097 ? 40  GLN A HG3  1 
ATOM   243  H  HG3  B GLN A 1 17  ? 6.17500   -17.87500 -5.06900 0.484 29.04003 ? 40  GLN A HG3  1 
ATOM   244  H  HE21 A GLN A 1 17  ? 2.46000   -15.39600 -7.78000 0.516 34.52568 ? 40  GLN A HE21 1 
ATOM   245  H  HE21 B GLN A 1 17  ? 4.79500   -19.14100 -7.27000 0.484 34.37206 ? 40  GLN A HE21 1 
ATOM   246  H  HE22 A GLN A 1 17  ? 1.75400   -16.70800 -7.78000 0.516 34.52568 ? 40  GLN A HE22 1 
ATOM   247  H  HE22 B GLN A 1 17  ? 3.58700   -19.81200 -6.71500 0.484 34.37206 ? 40  GLN A HE22 1 
ATOM   248  N  N    . SER A 1 18  ? 5.37300   -13.97300 -2.57300 1.000 15.80956 ? 41  SER A N    1 
ATOM   249  C  CA   . SER A 1 18  ? 4.72700   -12.82400 -1.96500 1.000 14.60594 ? 41  SER A CA   1 
ATOM   250  C  C    . SER A 1 18  ? 5.63200   -11.61100 -1.88900 1.000 13.41228 ? 41  SER A C    1 
ATOM   251  O  O    . SER A 1 18  ? 5.12800   -10.49300 -1.75100 1.000 14.76136 ? 41  SER A O    1 
ATOM   252  C  CB   . SER A 1 18  ? 4.30000   -13.17700 -0.53800 1.000 15.24313 ? 41  SER A CB   1 
ATOM   253  O  OG   . SER A 1 18  ? 5.41000   -13.18600 0.35500  1.000 15.31042 ? 41  SER A OG   1 
ATOM   254  H  H    A SER A 1 18  ? 5.56700   -14.60300 -2.02200 0.516 18.96952 ? 41  SER A H    1 
ATOM   255  H  H    B SER A 1 18  ? 5.52300   -14.62200 -2.03000 0.484 18.96952 ? 41  SER A H    1 
ATOM   256  H  HA   . SER A 1 18  ? 3.95000   -12.60000 -2.50100 1.000 17.52517 ? 41  SER A HA   1 
ATOM   257  H  HB2  . SER A 1 18  ? 3.65800   -12.51700 -0.23100 1.000 18.28980 ? 41  SER A HB2  1 
ATOM   258  H  HB3  . SER A 1 18  ? 3.89500   -14.05800 -0.54100 1.000 18.28980 ? 41  SER A HB3  1 
ATOM   259  H  HG   . SER A 1 18  ? 6.02300   -13.67100 0.04700  1.000 18.37055 ? 41  SER A HG   1 
ATOM   260  N  N    . GLY A 1 19  ? 6.94200   -11.80800 -1.87700 1.000 12.76917 ? 42  GLY A N    1 
ATOM   261  C  CA   . GLY A 1 19  ? 7.87900   -10.72300 -1.71900 1.000 12.97573 ? 42  GLY A CA   1 
ATOM   262  C  C    . GLY A 1 19  ? 8.13200   -10.28000 -0.29700 1.000 12.95817 ? 42  GLY A C    1 
ATOM   263  O  O    . GLY A 1 19  ? 9.01000   -9.43100  -0.09000 1.000 14.06023 ? 42  GLY A O    1 
ATOM   264  H  H    . GLY A 1 19  ? 7.31400   -12.57900 -1.96000 1.000 15.32106 ? 42  GLY A H    1 
ATOM   265  H  HA2  . GLY A 1 19  ? 8.73100   -10.99500 -2.09600 1.000 15.56893 ? 42  GLY A HA2  1 
ATOM   266  H  HA3  . GLY A 1 19  ? 7.54700   -9.95500  -2.21000 1.000 15.56893 ? 42  GLY A HA3  1 
ATOM   267  N  N    . GLY A 1 20  ? 7.40400   -10.81900 0.68300  1.000 12.34553 ? 43  GLY A N    1 
ATOM   268  C  CA   . GLY A 1 20  ? 7.55500   -10.39700 2.06200  1.000 12.29140 ? 43  GLY A CA   1 
ATOM   269  C  C    . GLY A 1 20  ? 8.10100   -11.46400 2.97900  1.000 11.38133 ? 43  GLY A C    1 
ATOM   270  O  O    . GLY A 1 20  ? 8.84300   -12.35900 2.54800  1.000 12.81641 ? 43  GLY A O    1 
ATOM   271  H  H    . GLY A 1 20  ? 6.81400   -11.43500 0.56800  1.000 14.81269 ? 43  GLY A H    1 
ATOM   272  H  HA2  . GLY A 1 20  ? 8.16000   -9.63900  2.09300  1.000 14.74772 ? 43  GLY A HA2  1 
ATOM   273  H  HA3  . GLY A 1 20  ? 6.68900   -10.12400 2.40400  1.000 14.74772 ? 43  GLY A HA3  1 
ATOM   274  N  N    . ARG A 1 21  ? 7.74800   -11.34000 4.25700  1.000 11.23992 ? 44  ARG A N    1 
ATOM   275  C  CA   . ARG A 1 21  ? 8.18400   -12.23600 5.31700  1.000 11.35138 ? 44  ARG A CA   1 
ATOM   276  C  C    . ARG A 1 21  ? 6.93600   -12.82300 5.96500  1.000 11.31424 ? 44  ARG A C    1 
ATOM   277  O  O    . ARG A 1 21  ? 6.07600   -12.08100 6.44800  1.000 11.25026 ? 44  ARG A O    1 
ATOM   278  C  CB   . ARG A 1 21  ? 9.04300   -11.48500 6.34200  1.000 12.29947 ? 44  ARG A CB   1 
ATOM   279  C  CG   . ARG A 1 21  ? 9.63800   -12.39400 7.42000  1.000 12.38337 ? 44  ARG A CG   1 
ATOM   280  C  CD   . ARG A 1 21  ? 10.67300  -11.67900 8.27600  1.000 12.47626 ? 44  ARG A CD   1 
ATOM   281  N  NE   . ARG A 1 21  ? 10.12100  -10.54100 9.00000  1.000 12.35984 ? 44  ARG A NE   1 
ATOM   282  C  CZ   . ARG A 1 21  ? 9.70100   -10.56100 10.25900 1.000 11.48378 ? 44  ARG A CZ   1 
ATOM   283  N  NH1  . ARG A 1 21  ? 9.79400   -11.64300 11.00900 1.000 12.69124 ? 44  ARG A NH1  1 
ATOM   284  N  NH2  . ARG A 1 21  ? 9.17200   -9.45800  10.77700 1.000 11.94482 ? 44  ARG A NH2  1 
ATOM   285  H  H    . ARG A 1 21  ? 7.23300   -10.71400 4.54400  1.000 13.48595 ? 44  ARG A H    1 
ATOM   286  H  HA   . ARG A 1 21  ? 8.71800   -12.96100 4.95600  1.000 13.61970 ? 44  ARG A HA   1 
ATOM   287  H  HB2  . ARG A 1 21  ? 9.77700   -11.05300 5.87900  1.000 14.75742 ? 44  ARG A HB2  1 
ATOM   288  H  HB3  . ARG A 1 21  ? 8.49200   -10.82100 6.78500  1.000 14.75742 ? 44  ARG A HB3  1 
ATOM   289  H  HG2  . ARG A 1 21  ? 8.92800   -12.70300 8.00300  1.000 14.85810 ? 44  ARG A HG2  1 
ATOM   290  H  HG3  . ARG A 1 21  ? 10.07100  -13.15000 6.99500  1.000 14.85810 ? 44  ARG A HG3  1 
ATOM   291  H  HD2  . ARG A 1 21  ? 11.03100  -12.30300 8.92700  1.000 14.96956 ? 44  ARG A HD2  1 
ATOM   292  H  HD3  . ARG A 1 21  ? 11.38500  -11.35200 7.70400  1.000 14.96956 ? 44  ARG A HD3  1 
ATOM   293  H  HE   . ARG A 1 21  ? 10.06200  -9.79500  8.57700  1.000 14.82986 ? 44  ARG A HE   1 
ATOM   294  H  HH11 . ARG A 1 21  ? 10.13500  -12.36300 10.68500 1.000 15.22754 ? 44  ARG A HH11 1 
ATOM   295  H  HH12 . ARG A 1 21  ? 9.51400   -11.62800 11.82200 1.000 15.22754 ? 44  ARG A HH12 1 
ATOM   296  H  HH21 . ARG A 1 21  ? 9.10600   -8.74700  10.29800 1.000 14.33183 ? 44  ARG A HH21 1 
ATOM   297  H  HH22 . ARG A 1 21  ? 8.89600   -9.45600  11.59100 1.000 14.33183 ? 44  ARG A HH22 1 
ATOM   298  N  N    . LEU A 1 22  ? 6.84500   -14.14800 5.95200  1.000 11.40640 ? 45  LEU A N    1 
ATOM   299  C  CA   . LEU A 1 22  ? 5.67500   -14.91000 6.35900  1.000 10.66146 ? 45  LEU A CA   1 
ATOM   300  C  C    . LEU A 1 22  ? 5.99900   -15.68500 7.62800  1.000 11.10344 ? 45  LEU A C    1 
ATOM   301  O  O    . LEU A 1 22  ? 7.04300   -16.33100 7.70500  1.000 11.58612 ? 45  LEU A O    1 
ATOM   302  C  CB   . LEU A 1 22  ? 5.31300   -15.91100 5.25700  1.000 12.10007 ? 45  LEU A CB   1 
ATOM   303  C  CG   . LEU A 1 22  ? 4.14900   -16.86200 5.52200  1.000 12.71519 ? 45  LEU A CG   1 
ATOM   304  C  CD1  . LEU A 1 22  ? 2.82800   -16.13600 5.65700  1.000 12.94862 ? 45  LEU A CD1  1 
ATOM   305  C  CD2  . LEU A 1 22  ? 4.07400   -17.88000 4.40000  1.000 14.43375 ? 45  LEU A CD2  1 
ATOM   306  H  H    . LEU A 1 22  ? 7.48800   -14.65700 5.69400  1.000 13.68573 ? 45  LEU A H    1 
ATOM   307  H  HA   . LEU A 1 22  ? 4.93100   -14.31200 6.53300  1.000 12.79180 ? 45  LEU A HA   1 
ATOM   308  H  HB2  . LEU A 1 22  ? 5.08600   -15.40600 4.46000  1.000 14.51814 ? 45  LEU A HB2  1 
ATOM   309  H  HB3  . LEU A 1 22  ? 6.09300   -16.46200 5.08900  1.000 14.51814 ? 45  LEU A HB3  1 
ATOM   310  H  HG   . LEU A 1 22  ? 4.30500   -17.31100 6.36800  1.000 15.25628 ? 45  LEU A HG   1 
ATOM   311  H  HD11 . LEU A 1 22  ? 2.12000   -16.78900 5.77800  1.000 15.53640 ? 45  LEU A HD11 1 
ATOM   312  H  HD12 . LEU A 1 22  ? 2.86800   -15.54700 6.42600  1.000 15.53640 ? 45  LEU A HD12 1 
ATOM   313  H  HD13 . LEU A 1 22  ? 2.66700   -15.61900 4.85200  1.000 15.53640 ? 45  LEU A HD13 1 
ATOM   314  H  HD21 . LEU A 1 22  ? 3.31600   -18.46500 4.55500  1.000 17.31854 ? 45  LEU A HD21 1 
ATOM   315  H  HD22 . LEU A 1 22  ? 3.96500   -17.41300 3.55700  1.000 17.31854 ? 45  LEU A HD22 1 
ATOM   316  H  HD23 . LEU A 1 22  ? 4.89400   -18.39800 4.38800  1.000 17.31854 ? 45  LEU A HD23 1 
ATOM   317  N  N    . GLY A 1 23  ? 5.08700   -15.64900 8.59700  1.000 10.32668 ? 46  GLY A N    1 
ATOM   318  C  CA   . GLY A 1 23  ? 5.20400   -16.43000 9.81900  1.000 10.20057 ? 46  GLY A CA   1 
ATOM   319  C  C    . GLY A 1 23  ? 3.94500   -17.23200 10.04100 1.000 10.04629 ? 46  GLY A C    1 
ATOM   320  O  O    . GLY A 1 23  ? 2.83700   -16.69800 9.99500  1.000 10.74049 ? 46  GLY A O    1 
ATOM   321  H  H    . GLY A 1 23  ? 4.37500   -15.16800 8.56800  1.000 12.39006 ? 46  GLY A H    1 
ATOM   322  H  HA2  . GLY A 1 23  ? 5.95800   -17.03800 9.75100  1.000 12.23873 ? 46  GLY A HA2  1 
ATOM   323  H  HA3  . GLY A 1 23  ? 5.34200   -15.84000 10.57600 1.000 12.23873 ? 46  GLY A HA3  1 
ATOM   324  N  N    . VAL A 1 24  ? 4.08600   -18.52300 10.28100 1.000 10.02752 ? 47  VAL A N    1 
ATOM   325  C  CA   . VAL A 1 24  ? 2.94300   -19.41500 10.43200 1.000 10.20325 ? 47  VAL A CA   1 
ATOM   326  C  C    . VAL A 1 24  ? 3.16000   -20.30900 11.64000 1.000 9.69590  ? 47  VAL A C    1 
ATOM   327  O  O    . VAL A 1 24  ? 4.24700   -20.86700 11.82700 1.000 10.68074 ? 47  VAL A O    1 
ATOM   328  C  CB   . VAL A 1 24  ? 2.73200   -20.29500 9.17400  1.000 11.02070 ? 47  VAL A CB   1 
ATOM   329  C  CG1  . VAL A 1 24  ? 1.56600   -21.24200 9.36600  1.000 11.73146 ? 47  VAL A CG1  1 
ATOM   330  C  CG2  . VAL A 1 24  ? 2.51400   -19.44900 7.93900  1.000 11.45183 ? 47  VAL A CG2  1 
ATOM   331  H  H    . VAL A 1 24  ? 4.84600   -18.91600 10.36300 1.000 12.03108 ? 47  VAL A H    1 
ATOM   332  H  HA   . VAL A 1 24  ? 2.15300   -18.87400 10.58200 1.000 12.24196 ? 47  VAL A HA   1 
ATOM   333  H  HB   . VAL A 1 24  ? 3.53700   -20.81900 9.04200  1.000 13.22289 ? 47  VAL A HB   1 
ATOM   334  H  HG11 . VAL A 1 24  ? 1.34100   -21.64300 8.51200  1.000 14.07580 ? 47  VAL A HG11 1 
ATOM   335  H  HG12 . VAL A 1 24  ? 1.82000   -21.93200 9.99800  1.000 14.07580 ? 47  VAL A HG12 1 
ATOM   336  H  HG13 . VAL A 1 24  ? 0.80700   -20.74400 9.70800  1.000 14.07580 ? 47  VAL A HG13 1 
ATOM   337  H  HG21 . VAL A 1 24  ? 2.38100   -20.03400 7.17600  1.000 13.74025 ? 47  VAL A HG21 1 
ATOM   338  H  HG22 . VAL A 1 24  ? 1.73100   -18.89300 8.07100  1.000 13.74025 ? 47  VAL A HG22 1 
ATOM   339  H  HG23 . VAL A 1 24  ? 3.29500   -18.89200 7.79600  1.000 13.74025 ? 47  VAL A HG23 1 
ATOM   340  N  N    . ALA A 1 25  ? 2.10500   -20.49100 12.42500 1.000 10.05291 ? 48  ALA A N    1 
ATOM   341  C  CA   . ALA A 1 25  ? 2.08100   -21.55400 13.42600 1.000 9.68340  ? 48  ALA A CA   1 
ATOM   342  C  C    . ALA A 1 25  ? 0.69300   -22.16500 13.44800 1.000 9.48650  ? 48  ALA A C    1 
ATOM   343  O  O    . ALA A 1 25  ? -0.28700  -21.47900 13.73100 1.000 9.96759  ? 48  ALA A O    1 
ATOM   344  C  CB   . ALA A 1 25  ? 2.45000   -21.03100 14.81700 1.000 10.50402 ? 48  ALA A CB   1 
ATOM   345  H  H    . ALA A 1 25  ? 1.39100   -20.01200 12.39900 1.000 12.06155 ? 48  ALA A H    1 
ATOM   346  H  HA   . ALA A 1 25  ? 2.72300   -22.23800 13.17700 1.000 11.61813 ? 48  ALA A HA   1 
ATOM   347  H  HB1  . ALA A 1 25  ? 2.44500   -21.77000 15.44400 1.000 12.60287 ? 48  ALA A HB1  1 
ATOM   348  H  HB2  . ALA A 1 25  ? 3.33400   -20.63400 14.78000 1.000 12.60287 ? 48  ALA A HB2  1 
ATOM   349  H  HB3  . ALA A 1 25  ? 1.79900   -20.36400 15.08600 1.000 12.60287 ? 48  ALA A HB3  1 
ATOM   350  N  N    . LEU A 1 26  ? 0.61100   -23.45300 13.12500 1.000 10.92905 ? 49  LEU A N    1 
ATOM   351  C  CA   . LEU A 1 26  ? -0.60400  -24.25300 13.24000 1.000 10.39660 ? 49  LEU A CA   1 
ATOM   352  C  C    . LEU A 1 26  ? -0.41500  -25.22200 14.39700 1.000 10.47892 ? 49  LEU A C    1 
ATOM   353  O  O    . LEU A 1 26  ? 0.60000   -25.92200 14.45300 1.000 12.42255 ? 49  LEU A O    1 
ATOM   354  C  CB   . LEU A 1 26  ? -0.82300  -25.06800 11.96200 1.000 11.51747 ? 49  LEU A CB   1 
ATOM   355  C  CG   . LEU A 1 26  ? -2.02600  -26.01800 11.97700 1.000 12.88516 ? 49  LEU A CG   1 
ATOM   356  C  CD1  . LEU A 1 26  ? -3.34900  -25.29000 11.83100 1.000 14.19314 ? 49  LEU A CD1  1 
ATOM   357  C  CD2  . LEU A 1 26  ? -1.88000  -27.10800 10.89500 1.000 14.77820 ? 49  LEU A CD2  1 
ATOM   358  H  H    . LEU A 1 26  ? 1.27700   -23.90600 12.82300 1.000 13.11291 ? 49  LEU A H    1 
ATOM   359  H  HA   . LEU A 1 26  ? -1.37100  -23.68100 13.39800 1.000 12.47396 ? 49  LEU A HA   1 
ATOM   360  H  HB2  . LEU A 1 26  ? -0.95300  -24.45000 11.22600 1.000 13.81901 ? 49  LEU A HB2  1 
ATOM   361  H  HB3  . LEU A 1 26  ? -0.03100  -25.60700 11.80600 1.000 13.81901 ? 49  LEU A HB3  1 
ATOM   362  H  HG   . LEU A 1 26  ? -2.04200  -26.44900 12.84600 1.000 15.46024 ? 49  LEU A HG   1 
ATOM   363  H  HD11 . LEU A 1 26  ? -4.06900  -25.93900 11.83200 1.000 17.02981 ? 49  LEU A HD11 1 
ATOM   364  H  HD12 . LEU A 1 26  ? -3.45500  -24.67600 12.57400 1.000 17.02981 ? 49  LEU A HD12 1 
ATOM   365  H  HD13 . LEU A 1 26  ? -3.34800  -24.79900 10.99400 1.000 17.02981 ? 49  LEU A HD13 1 
ATOM   366  H  HD21 . LEU A 1 26  ? -2.69900  -27.62500 10.85600 1.000 17.73189 ? 49  LEU A HD21 1 
ATOM   367  H  HD22 . LEU A 1 26  ? -1.71500  -26.68200 10.03900 1.000 17.73189 ? 49  LEU A HD22 1 
ATOM   368  H  HD23 . LEU A 1 26  ? -1.13500  -27.68400 11.12600 1.000 17.73189 ? 49  LEU A HD23 1 
ATOM   369  N  N    . ILE A 1 27  ? -1.38100  -25.27200 15.31100 1.000 10.07949 ? 50  ILE A N    1 
ATOM   370  C  CA   . ILE A 1 27  ? -1.45900  -26.33000 16.31300 1.000 10.46918 ? 50  ILE A CA   1 
ATOM   371  C  C    . ILE A 1 27  ? -2.65300  -27.19500 15.94900 1.000 10.47440 ? 50  ILE A C    1 
ATOM   372  O  O    . ILE A 1 27  ? -3.77500  -26.69000 15.83000 1.000 10.86604 ? 50  ILE A O    1 
ATOM   373  C  CB   . ILE A 1 27  ? -1.62700  -25.77300 17.73300 1.000 11.05724 ? 50  ILE A CB   1 
ATOM   374  C  CG1  . ILE A 1 27  ? -0.43400  -24.89700 18.11500 1.000 11.45456 ? 50  ILE A CG1  1 
ATOM   375  C  CG2  . ILE A 1 27  ? -1.82700  -26.92700 18.73000 1.000 12.54748 ? 50  ILE A CG2  1 
ATOM   376  C  CD1  . ILE A 1 27  ? -0.65400  -24.05400 19.37700 1.000 14.08815 ? 50  ILE A CD1  1 
ATOM   377  H  H    . ILE A 1 27  ? -2.01500  -24.69300 15.37000 1.000 12.09343 ? 50  ILE A H    1 
ATOM   378  H  HA   . ILE A 1 27  ? -0.64500  -26.85700 16.28700 1.000 12.56107 ? 50  ILE A HA   1 
ATOM   379  H  HB   . ILE A 1 27  ? -2.41700  -25.21000 17.75900 1.000 13.26674 ? 50  ILE A HB   1 
ATOM   380  H  HG12 . ILE A 1 27  ? 0.33300   -25.47000 18.27300 1.000 13.74352 ? 50  ILE A HG12 1 
ATOM   381  H  HG13 . ILE A 1 27  ? -0.24800  -24.28900 17.38300 1.000 13.74352 ? 50  ILE A HG13 1 
ATOM   382  H  HG21 . ILE A 1 27  ? -1.78800  -26.57400 19.63300 1.000 15.05502 ? 50  ILE A HG21 1 
ATOM   383  H  HG22 . ILE A 1 27  ? -2.69200  -27.33500 18.57100 1.000 15.05502 ? 50  ILE A HG22 1 
ATOM   384  H  HG23 . ILE A 1 27  ? -1.12300  -27.58100 18.60000 1.000 15.05502 ? 50  ILE A HG23 1 
ATOM   385  H  HD11 . ILE A 1 27  ? 0.13100   -23.50400 19.53000 1.000 16.90383 ? 50  ILE A HD11 1 
ATOM   386  H  HD12 . ILE A 1 27  ? -1.43300  -23.49000 19.24800 1.000 16.90383 ? 50  ILE A HD12 1 
ATOM   387  H  HD13 . ILE A 1 27  ? -0.79500  -24.64600 20.13200 1.000 16.90383 ? 50  ILE A HD13 1 
ATOM   388  N  N    . ASN A 1 28  ? -2.43100  -28.49400 15.77800 1.000 11.48322 ? 51  ASN A N    1 
ATOM   389  C  CA   . ASN A 1 28  ? -3.50900  -29.43000 15.49800 1.000 11.54726 ? 51  ASN A CA   1 
ATOM   390  C  C    . ASN A 1 28  ? -3.78600  -30.22100 16.77200 1.000 11.11338 ? 51  ASN A C    1 
ATOM   391  O  O    . ASN A 1 28  ? -2.96800  -31.05600 17.18100 1.000 12.21505 ? 51  ASN A O    1 
ATOM   392  C  CB   . ASN A 1 28  ? -3.12300  -30.35000 14.34500 1.000 12.46918 ? 51  ASN A CB   1 
ATOM   393  C  CG   . ASN A 1 28  ? -4.23200  -31.28000 13.95500 1.000 13.19466 ? 51  ASN A CG   1 
ATOM   394  O  OD1  . ASN A 1 28  ? -5.25600  -31.38700 14.64500 1.000 13.24049 ? 51  ASN A OD1  1 
ATOM   395  N  ND2  . ASN A 1 28  ? -4.03800  -31.97500 12.84900 1.000 16.17861 ? 51  ASN A ND2  1 
ATOM   396  H  H    . ASN A 1 28  ? -1.65300  -28.86000 15.82100 1.000 13.77791 ? 51  ASN A H    1 
ATOM   397  H  HA   . ASN A 1 28  ? -4.31500  -28.95000 15.25100 1.000 13.85477 ? 51  ASN A HA   1 
ATOM   398  H  HB2  . ASN A 1 28  ? -2.89700  -29.81100 13.57100 1.000 14.96106 ? 51  ASN A HB2  1 
ATOM   399  H  HB3  . ASN A 1 28  ? -2.35900  -30.88700 14.61000 1.000 14.96106 ? 51  ASN A HB3  1 
ATOM   400  H  HD21 . ASN A 1 28  ? -4.64000  -32.52500 12.57600 1.000 19.41238 ? 51  ASN A HD21 1 
ATOM   401  H  HD22 . ASN A 1 28  ? -3.31000  -31.87800 12.40200 1.000 19.41238 ? 51  ASN A HD22 1 
ATOM   402  N  N    . THR A 1 29  ? -4.92300  -29.93900 17.42200 1.000 11.30504 ? 52  THR A N    1 
ATOM   403  C  CA   . THR A 1 29  ? -5.20100  -30.61800 18.68800 1.000 12.32169 ? 52  THR A CA   1 
ATOM   404  C  C    . THR A 1 29  ? -5.61900  -32.07400 18.51200 1.000 12.77577 ? 52  THR A C    1 
ATOM   405  O  O    . THR A 1 29  ? -5.72700  -32.77600 19.52000 1.000 13.76557 ? 52  THR A O    1 
ATOM   406  C  CB   . THR A 1 29  ? -6.22300  -29.86000 19.55600 1.000 12.48162 ? 52  THR A CB   1 
ATOM   407  O  OG1  . THR A 1 29  ? -7.55100  -29.98000 19.03100 1.000 12.42453 ? 52  THR A OG1  1 
ATOM   408  C  CG2  . THR A 1 29  ? -5.84600  -28.39300 19.72600 1.000 12.84758 ? 52  THR A CG2  1 
ATOM   409  H  H    . THR A 1 29  ? -5.52300  -29.38100 17.15900 1.000 13.56410 ? 52  THR A H    1 
ATOM   410  H  HA   . THR A 1 29  ? -4.37400  -30.60800 19.19600 1.000 14.78408 ? 52  THR A HA   1 
ATOM   411  H  HB   . THR A 1 29  ? -6.21600  -30.26400 20.43800 1.000 14.97600 ? 52  THR A HB   1 
ATOM   412  H  HG1  . THR A 1 29  ? -7.68200  -29.39100 18.44600 1.000 14.90749 ? 52  THR A HG1  1 
ATOM   413  H  HG21 . THR A 1 29  ? -6.45600  -27.96400 20.34600 1.000 15.41515 ? 52  THR A HG21 1 
ATOM   414  H  HG22 . THR A 1 29  ? -4.94200  -28.32100 20.07200 1.000 15.41515 ? 52  THR A HG22 1 
ATOM   415  H  HG23 . THR A 1 29  ? -5.89300  -27.93800 18.87100 1.000 15.41515 ? 52  THR A HG23 1 
ATOM   416  N  N    . ALA A 1 30  ? -5.82200  -32.54600 17.27300 1.000 13.10325 ? 53  ALA A N    1 
ATOM   417  C  CA   . ALA A 1 30  ? -6.10400  -33.96300 17.06000 1.000 14.02797 ? 53  ALA A CA   1 
ATOM   418  C  C    . ALA A 1 30  ? -4.95500  -34.82500 17.56100 1.000 14.60269 ? 53  ALA A C    1 
ATOM   419  O  O    . ALA A 1 30  ? -5.18500  -35.87200 18.18100 1.000 16.41301 ? 53  ALA A O    1 
ATOM   420  C  CB   . ALA A 1 30  ? -6.36600  -34.24300 15.57800 1.000 14.52126 ? 53  ALA A CB   1 
ATOM   421  H  H    . ALA A 1 30  ? -5.80200  -32.07200 16.55500 1.000 15.72195 ? 53  ALA A H    1 
ATOM   422  H  HA   . ALA A 1 30  ? -6.90700  -34.19500 17.55300 1.000 16.83162 ? 53  ALA A HA   1 
ATOM   423  H  HB1  . ALA A 1 30  ? -6.56000  -35.18700 15.46500 1.000 17.42356 ? 53  ALA A HB1  1 
ATOM   424  H  HB2  . ALA A 1 30  ? -7.12400  -33.71300 15.28600 1.000 17.42356 ? 53  ALA A HB2  1 
ATOM   425  H  HB3  . ALA A 1 30  ? -5.57800  -34.00400 15.06700 1.000 17.42356 ? 53  ALA A HB3  1 
ATOM   426  N  N    . ASP A 1 31  ? -3.71000  -34.42200 17.28200 1.000 14.30484 ? 54  ASP A N    1 
ATOM   427  C  CA   . ASP A 1 31  ? -2.53400  -35.22500 17.60700 1.000 14.85918 ? 54  ASP A CA   1 
ATOM   428  C  C    . ASP A 1 31  ? -1.45000  -34.42100 18.32100 1.000 13.70261 ? 54  ASP A C    1 
ATOM   429  O  O    . ASP A 1 31  ? -0.32700  -34.91900 18.48400 1.000 14.64845 ? 54  ASP A O    1 
ATOM   430  C  CB   . ASP A 1 31  ? -1.95700  -35.92100 16.36300 1.000 16.99656 ? 54  ASP A CB   1 
ATOM   431  C  CG   . ASP A 1 31  ? -1.49200  -34.94600 15.29900 1.000 18.67514 ? 54  ASP A CG   1 
ATOM   432  O  OD1  . ASP A 1 31  ? -1.69500  -33.72800 15.46300 1.000 16.65205 ? 54  ASP A OD1  1 
ATOM   433  O  OD2  . ASP A 1 31  ? -0.91900  -35.40500 14.29100 1.000 21.99451 ? 54  ASP A OD2  1 
ATOM   434  H  H    . ASP A 1 31  ? -3.52100  -33.67500 16.89900 1.000 17.16386 ? 54  ASP A H    1 
ATOM   435  H  HA   . ASP A 1 31  ? -2.81600  -35.93000 18.21000 1.000 17.82907 ? 54  ASP A HA   1 
ATOM   436  H  HB2  . ASP A 1 31  ? -1.19500  -36.45900 16.62900 1.000 20.39392 ? 54  ASP A HB2  1 
ATOM   437  H  HB3  . ASP A 1 31  ? -2.64200  -36.48500 15.97200 1.000 20.39392 ? 54  ASP A HB3  1 
ATOM   438  N  N    . ASN A 1 32  ? -1.76200  -33.20400 18.76300 1.000 12.97940 ? 55  ASN A N    1 
ATOM   439  C  CA   . ASN A 1 32  ? -0.81400  -32.34700 19.46600 1.000 12.56498 ? 55  ASN A CA   1 
ATOM   440  C  C    . ASN A 1 32  ? 0.41300   -32.03300 18.61900 1.000 13.03539 ? 55  ASN A C    1 
ATOM   441  O  O    . ASN A 1 32  ? 1.52400   -31.91400 19.13400 1.000 15.37358 ? 55  ASN A O    1 
ATOM   442  C  CB   . ASN A 1 32  ? -0.40900  -32.92000 20.82000 1.000 13.58734 ? 55  ASN A CB   1 
ATOM   443  C  CG   . ASN A 1 32  ? 0.08200   -31.85300 21.77000 1.000 14.38167 ? 55  ASN A CG   1 
ATOM   444  O  OD1  . ASN A 1 32  ? -0.30500  -30.68700 21.67000 1.000 15.83663 ? 55  ASN A OD1  1 
ATOM   445  N  ND2  . ASN A 1 32  ? 0.93300   -32.24300 22.70600 1.000 15.62860 ? 55  ASN A ND2  1 
ATOM   446  H  H    . ASN A 1 32  ? -2.53700  -32.84400 18.66500 1.000 15.57333 ? 55  ASN A H    1 
ATOM   447  H  HA   . ASN A 1 32  ? -1.26700  -31.50500 19.63300 1.000 15.07603 ? 55  ASN A HA   1 
ATOM   448  H  HB2  . ASN A 1 32  ? -1.17800  -33.35400 21.22400 1.000 16.30286 ? 55  ASN A HB2  1 
ATOM   449  H  HB3  . ASN A 1 32  ? 0.30500   -33.56300 20.69300 1.000 16.30286 ? 55  ASN A HB3  1 
ATOM   450  H  HD21 . ASN A 1 32  ? 1.24100   -31.67200 23.27100 1.000 18.75237 ? 55  ASN A HD21 1 
ATOM   451  H  HD22 . ASN A 1 32  ? 1.17700   -33.06600 22.75000 1.000 18.75237 ? 55  ASN A HD22 1 
ATOM   452  N  N    . SER A 1 33  ? 0.20700   -31.87500 17.31800 1.000 13.43948 ? 56  SER A N    1 
ATOM   453  C  CA   . SER A 1 33  ? 1.28600   -31.54700 16.40800 1.000 13.61744 ? 56  SER A CA   1 
ATOM   454  C  C    . SER A 1 33  ? 1.23500   -30.07400 16.02000 1.000 12.99196 ? 56  SER A C    1 
ATOM   455  O  O    . SER A 1 33  ? 0.26000   -29.36200 16.25800 1.000 12.29923 ? 56  SER A O    1 
ATOM   456  C  CB   . SER A 1 33  ? 1.20700   -32.41800 15.15200 1.000 15.36464 ? 56  SER A CB   1 
ATOM   457  O  OG   . SER A 1 33  ? 0.04200   -32.12000 14.41200 1.000 15.87949 ? 56  SER A OG   1 
ATOM   458  H  H    . SER A 1 33  ? -0.56000  -31.95500 16.93700 1.000 16.12543 ? 56  SER A H    1 
ATOM   459  H  HA   . SER A 1 33  ? 2.13100   -31.71600 16.85300 1.000 16.33898 ? 56  SER A HA   1 
ATOM   460  H  HB2  . SER A 1 33  ? 1.98500   -32.24800 14.59900 1.000 18.43562 ? 56  SER A HB2  1 
ATOM   461  H  HB3  . SER A 1 33  ? 1.18500   -33.35200 15.41500 1.000 18.43562 ? 56  SER A HB3  1 
ATOM   462  H  HG   . SER A 1 33  ? -0.64100  -32.28400 14.87400 1.000 19.05343 ? 56  SER A HG   1 
ATOM   463  N  N    A GLN A 1 34  ? 2.34000   -29.61900 15.42500 0.513 13.42532 ? 57  GLN A N    1 
ATOM   464  N  N    B GLN A 1 34  ? 2.30000   -29.62900 15.36600 0.487 13.54699 ? 57  GLN A N    1 
ATOM   465  C  CA   A GLN A 1 34  ? 2.49700   -28.24800 14.96800 0.513 13.32364 ? 57  GLN A CA   1 
ATOM   466  C  CA   B GLN A 1 34  ? 2.37100   -28.25000 14.92700 0.487 13.88105 ? 57  GLN A CA   1 
ATOM   467  C  C    A GLN A 1 34  ? 3.06800   -28.23000 13.55600 0.513 12.51985 ? 57  GLN A C    1 
ATOM   468  C  C    B GLN A 1 34  ? 3.12300   -28.16500 13.61400 0.487 13.04921 ? 57  GLN A C    1 
ATOM   469  O  O    A GLN A 1 34  ? 3.76300   -29.15800 13.13100 0.513 13.78430 ? 57  GLN A O    1 
ATOM   470  O  O    B GLN A 1 34  ? 4.02400   -28.96200 13.33400 0.487 14.18584 ? 57  GLN A O    1 
ATOM   471  C  CB   A GLN A 1 34  ? 3.45300   -27.45300 15.87300 0.513 15.50653 ? 57  GLN A CB   1 
ATOM   472  C  CB   B GLN A 1 34  ? 3.08800   -27.38600 15.95100 0.487 15.56020 ? 57  GLN A CB   1 
ATOM   473  C  CG   A GLN A 1 34  ? 2.93800   -27.20400 17.27900 0.513 17.16469 ? 57  GLN A CG   1 
ATOM   474  C  CG   B GLN A 1 34  ? 4.50700   -27.84300 16.18100 0.487 17.06160 ? 57  GLN A CG   1 
ATOM   475  C  CD   A GLN A 1 34  ? 3.94500   -26.46700 18.14400 0.513 18.75788 ? 57  GLN A CD   1 
ATOM   476  C  CD   B GLN A 1 34  ? 5.11500   -27.21200 17.40100 0.487 18.61552 ? 57  GLN A CD   1 
ATOM   477  O  OE1  A GLN A 1 34  ? 3.68800   -25.35500 18.60800 0.513 20.02416 ? 57  GLN A OE1  1 
ATOM   478  O  OE1  B GLN A 1 34  ? 4.51500   -26.33100 18.02200 0.487 18.68872 ? 57  GLN A OE1  1 
ATOM   479  N  NE2  A GLN A 1 34  ? 5.10000   -27.08800 18.36900 0.513 20.66337 ? 57  GLN A NE2  1 
ATOM   480  N  NE2  B GLN A 1 34  ? 6.31100   -27.66100 17.76100 0.487 19.67849 ? 57  GLN A NE2  1 
ATOM   481  H  H    A GLN A 1 34  ? 3.03300   -30.10600 15.27300 0.513 16.10844 ? 57  GLN A H    1 
ATOM   482  H  H    B GLN A 1 34  ? 2.98800   -30.10600 15.16800 0.487 16.25443 ? 57  GLN A H    1 
ATOM   483  H  HA   A GLN A 1 34  ? 1.62500   -27.82400 14.96600 0.513 15.98642 ? 57  GLN A HA   1 
ATOM   484  H  HA   B GLN A 1 34  ? 1.46800   -27.92200 14.79000 0.487 16.65532 ? 57  GLN A HA   1 
ATOM   485  H  HB2  A GLN A 1 34  ? 4.28500   -27.94500 15.95000 0.513 18.60588 ? 57  GLN A HB2  1 
ATOM   486  H  HB2  B GLN A 1 34  ? 3.11200   -26.47000 15.63400 0.487 18.67029 ? 57  GLN A HB2  1 
ATOM   487  H  HB3  A GLN A 1 34  ? 3.61500   -26.58800 15.46500 0.513 18.60588 ? 57  GLN A HB3  1 
ATOM   488  H  HB3  B GLN A 1 34  ? 2.61400   -27.43300 16.79600 0.487 18.67029 ? 57  GLN A HB3  1 
ATOM   489  H  HG2  A GLN A 1 34  ? 2.13100   -26.66700 17.23200 0.513 20.59568 ? 57  GLN A HG2  1 
ATOM   490  H  HG2  B GLN A 1 34  ? 4.51600   -28.80500 16.30200 0.487 20.47197 ? 57  GLN A HG2  1 
ATOM   491  H  HG3  A GLN A 1 34  ? 2.74500   -28.05600 17.70200 0.513 20.59568 ? 57  GLN A HG3  1 
ATOM   492  H  HG3  B GLN A 1 34  ? 5.04800   -27.60000 15.41300 0.487 20.47197 ? 57  GLN A HG3  1 
ATOM   493  H  HE21 A GLN A 1 34  ? 5.24300   -27.86500 18.03000 0.513 24.79409 ? 57  GLN A HE21 1 
ATOM   494  H  HE21 B GLN A 1 34  ? 6.69400   -28.28000 17.30300 0.487 23.61224 ? 57  GLN A HE21 1 
ATOM   495  H  HE22 A GLN A 1 34  ? 5.70300   -26.71200 18.85300 0.513 24.79409 ? 57  GLN A HE22 1 
ATOM   496  H  HE22 B GLN A 1 34  ? 6.70300   -27.33300 18.45300 0.487 23.61224 ? 57  GLN A HE22 1 
ATOM   497  N  N    . ILE A 1 35  ? 2.74700   -27.16400 12.82900 1.000 11.41917 ? 58  ILE A N    1 
ATOM   498  C  CA   . ILE A 1 35  ? 3.44100   -26.79100 11.59900 1.000 11.59528 ? 58  ILE A CA   1 
ATOM   499  C  C    . ILE A 1 35  ? 3.91600   -25.36200 11.81600 1.000 11.56482 ? 58  ILE A C    1 
ATOM   500  O  O    . ILE A 1 35  ? 3.10600   -24.48700 12.13000 1.000 11.60614 ? 58  ILE A O    1 
ATOM   501  C  CB   . ILE A 1 35  ? 2.53500   -26.89100 10.36100 1.000 13.86606 ? 58  ILE A CB   1 
ATOM   502  C  CG1  . ILE A 1 35  ? 2.11000   -28.34700 10.14900 1.000 15.50665 ? 58  ILE A CG1  1 
ATOM   503  C  CG2  . ILE A 1 35  ? 3.25400   -26.32400 9.13600  1.000 16.09403 ? 58  ILE A CG2  1 
ATOM   504  C  CD1  . ILE A 1 35  ? 1.15600   -28.56200 9.00200  1.000 17.41549 ? 58  ILE A CD1  1 
ATOM   505  H  H    . ILE A 1 35  ? 2.11100   -26.62100 13.03200 1.000 13.70105 ? 58  ILE A H    1 
ATOM   506  H  HA   . ILE A 1 35  ? 4.19900   -27.37600 11.44500 1.000 13.91239 ? 58  ILE A HA   1 
ATOM   507  H  HB   . ILE A 1 35  ? 1.73300   -26.36200 10.50100 1.000 16.63732 ? 58  ILE A HB   1 
ATOM   508  H  HG12 . ILE A 1 35  ? 2.90300   -28.87700 9.97300  1.000 18.60603 ? 58  ILE A HG12 1 
ATOM   509  H  HG13 . ILE A 1 35  ? 1.67300   -28.66200 10.95500 1.000 18.60603 ? 58  ILE A HG13 1 
ATOM   510  H  HG21 . ILE A 1 35  ? 2.71000   -26.48100 8.34900  1.000 19.31088 ? 58  ILE A HG21 1 
ATOM   511  H  HG22 . ILE A 1 35  ? 3.38800   -25.37100 9.26100  1.000 19.31088 ? 58  ILE A HG22 1 
ATOM   512  H  HG23 . ILE A 1 35  ? 4.11100   -26.76800 9.04000  1.000 19.31088 ? 58  ILE A HG23 1 
ATOM   513  H  HD11 . ILE A 1 35  ? 0.79300   -29.46000 9.05800  1.000 20.89664 ? 58  ILE A HD11 1 
ATOM   514  H  HD12 . ILE A 1 35  ? 0.44000   -27.91100 9.06000  1.000 20.89664 ? 58  ILE A HD12 1 
ATOM   515  H  HD13 . ILE A 1 35  ? 1.63700   -28.45100 8.16700  1.000 20.89664 ? 58  ILE A HD13 1 
ATOM   516  N  N    . LEU A 1 36  ? 5.21800   -25.13200 11.66400 1.000 11.30375 ? 59  LEU A N    1 
ATOM   517  C  CA   . LEU A 1 36  ? 5.87500   -23.88000 12.02100 1.000 11.93552 ? 59  LEU A CA   1 
ATOM   518  C  C    . LEU A 1 36  ? 6.69000   -23.34900 10.85100 1.000 11.97461 ? 59  LEU A C    1 
ATOM   519  O  O    . LEU A 1 36  ? 7.39600   -24.10400 10.17900 1.000 13.65953 ? 59  LEU A O    1 
ATOM   520  C  CB   . LEU A 1 36  ? 6.82300   -24.13300 13.19000 1.000 12.50007 ? 59  LEU A CB   1 
ATOM   521  C  CG   . LEU A 1 36  ? 6.18400   -24.73600 14.44400 1.000 14.31022 ? 59  LEU A CG   1 
ATOM   522  C  CD1  . LEU A 1 36  ? 7.26700   -25.01900 15.49000 1.000 17.75996 ? 59  LEU A CD1  1 
ATOM   523  C  CD2  . LEU A 1 36  ? 5.09200   -23.83400 15.03500 1.000 14.74029 ? 59  LEU A CD2  1 
ATOM   524  H  H    . LEU A 1 36  ? 5.76500   -25.71300 11.34100 1.000 13.56256 ? 59  LEU A H    1 
ATOM   525  H  HA   . LEU A 1 36  ? 5.20800   -23.21300 12.24600 1.000 14.32067 ? 59  LEU A HA   1 
ATOM   526  H  HB2  . LEU A 1 36  ? 7.51400   -24.74600 12.89400 1.000 14.99814 ? 59  LEU A HB2  1 
ATOM   527  H  HB3  . LEU A 1 36  ? 7.22000   -23.28600 13.44800 1.000 14.99814 ? 59  LEU A HB3  1 
ATOM   528  H  HG   . LEU A 1 36  ? 5.75100   -25.56800 14.19400 1.000 17.17031 ? 59  LEU A HG   1 
ATOM   529  H  HD11 . LEU A 1 36  ? 6.86800   -25.48800 16.23900 1.000 21.31000 ? 59  LEU A HD11 1 
ATOM   530  H  HD12 . LEU A 1 36  ? 7.95900   -25.56700 15.08800 1.000 21.31000 ? 59  LEU A HD12 1 
ATOM   531  H  HD13 . LEU A 1 36  ? 7.64400   -24.17700 15.79000 1.000 21.31000 ? 59  LEU A HD13 1 
ATOM   532  H  HD21 . LEU A 1 36  ? 4.78400   -24.21800 15.87100 1.000 17.68640 ? 59  LEU A HD21 1 
ATOM   533  H  HD22 . LEU A 1 36  ? 5.46300   -22.95200 15.19300 1.000 17.68640 ? 59  LEU A HD22 1 
ATOM   534  H  HD23 . LEU A 1 36  ? 4.35600   -23.77600 14.40600 1.000 17.68640 ? 59  LEU A HD23 1 
ATOM   535  N  N    . TYR A 1 37  ? 6.60100   -22.04100 10.61000 1.000 10.99707 ? 60  TYR A N    1 
ATOM   536  C  CA   . TYR A 1 37  ? 7.39800   -21.36800 9.58600  1.000 11.33637 ? 60  TYR A CA   1 
ATOM   537  C  C    . TYR A 1 37  ? 7.74400   -19.98800 10.12500 1.000 10.70443 ? 60  TYR A C    1 
ATOM   538  O  O    . TYR A 1 37  ? 6.84600   -19.18500 10.36900 1.000 10.82672 ? 60  TYR A O    1 
ATOM   539  C  CB   . TYR A 1 37  ? 6.62200   -21.27300 8.26900  1.000 11.59672 ? 60  TYR A CB   1 
ATOM   540  C  CG   . TYR A 1 37  ? 7.48100   -20.79700 7.12500  1.000 13.01062 ? 60  TYR A CG   1 
ATOM   541  C  CD1  . TYR A 1 37  ? 7.61700   -19.44300 6.84800  1.000 12.92850 ? 60  TYR A CD1  1 
ATOM   542  C  CD2  . TYR A 1 37  ? 8.17600   -21.70000 6.33100  1.000 13.97237 ? 60  TYR A CD2  1 
ATOM   543  C  CE1  . TYR A 1 37  ? 8.42300   -19.00400 5.81300  1.000 13.08098 ? 60  TYR A CE1  1 
ATOM   544  C  CE2  . TYR A 1 37  ? 8.98500   -21.26600 5.28500  1.000 14.72848 ? 60  TYR A CE2  1 
ATOM   545  C  CZ   . TYR A 1 37  ? 9.10000   -19.92000 5.03700  1.000 14.14242 ? 60  TYR A CZ   1 
ATOM   546  O  OH   . TYR A 1 37  ? 9.91400   -19.50900 4.00700  1.000 15.77018 ? 60  TYR A OH   1 
ATOM   547  H  H    . TYR A 1 37  ? 6.07400   -21.51200 11.03600 1.000 13.19454 ? 60  TYR A H    1 
ATOM   548  H  HA   . TYR A 1 37  ? 8.22000   -21.85200 9.41000  1.000 13.60170 ? 60  TYR A HA   1 
ATOM   549  H  HB2  . TYR A 1 37  ? 6.27500   -22.15000 8.04100  1.000 13.91412 ? 60  TYR A HB2  1 
ATOM   550  H  HB3  . TYR A 1 37  ? 5.89000   -20.64500 8.37700  1.000 13.91412 ? 60  TYR A HB3  1 
ATOM   551  H  HD1  . TYR A 1 37  ? 7.15800   -18.82200 7.36600  1.000 15.51225 ? 60  TYR A HD1  1 
ATOM   552  H  HD2  . TYR A 1 37  ? 8.09900   -22.61100 6.50200  1.000 16.76489 ? 60  TYR A HD2  1 
ATOM   553  H  HE1  . TYR A 1 37  ? 8.50800   -18.09400 5.64100  1.000 15.69523 ? 60  TYR A HE1  1 
ATOM   554  H  HE2  . TYR A 1 37  ? 9.44400   -21.88200 4.76000  1.000 17.67223 ? 60  TYR A HE2  1 
ATOM   555  H  HH   . TYR A 1 37  ? 10.03000  -18.67800 4.04700  1.000 18.92227 ? 60  TYR A HH   1 
ATOM   556  N  N    . ARG A 1 38  ? 9.03100   -19.72600 10.34100 1.000 11.44597 ? 61  ARG A N    1 
ATOM   557  C  CA   . ARG A 1 38  ? 9.47700   -18.49800 11.00800 1.000 11.20025 ? 61  ARG A CA   1 
ATOM   558  C  C    . ARG A 1 38  ? 8.71500   -18.28700 12.31200 1.000 11.42447 ? 61  ARG A C    1 
ATOM   559  O  O    . ARG A 1 38  ? 8.43800   -17.16000 12.71900 1.000 11.91461 ? 61  ARG A O    1 
ATOM   560  C  CB   . ARG A 1 38  ? 9.35100   -17.27700 10.10100 1.000 11.10225 ? 61  ARG A CB   1 
ATOM   561  C  CG   . ARG A 1 38  ? 10.18700  -17.36700 8.83700  1.000 12.05625 ? 61  ARG A CG   1 
ATOM   562  C  CD   . ARG A 1 38  ? 10.27900  -16.01700 8.14900  1.000 12.08761 ? 61  ARG A CD   1 
ATOM   563  N  NE   . ARG A 1 38  ? 10.89500  -16.12800 6.83100  1.000 13.33463 ? 61  ARG A NE   1 
ATOM   564  C  CZ   . ARG A 1 38  ? 12.17400  -16.38900 6.60900  1.000 14.64545 ? 61  ARG A CZ   1 
ATOM   565  N  NH1  . ARG A 1 38  ? 13.05200  -16.44300 7.59900  1.000 15.27032 ? 61  ARG A NH1  1 
ATOM   566  N  NH2  . ARG A 1 38  ? 12.58400  -16.59200 5.36000  1.000 16.78519 ? 61  ARG A NH2  1 
ATOM   567  H  H    . ARG A 1 38  ? 9.67500   -20.24800 10.11000 1.000 13.73322 ? 61  ARG A H    1 
ATOM   568  H  HA   . ARG A 1 38  ? 10.41800  -18.59900 11.22000 1.000 13.43834 ? 61  ARG A HA   1 
ATOM   569  H  HB2  . ARG A 1 38  ? 8.42300   -17.17900 9.83600  1.000 13.32075 ? 61  ARG A HB2  1 
ATOM   570  H  HB3  . ARG A 1 38  ? 9.64100   -16.49200 10.59200 1.000 13.32075 ? 61  ARG A HB3  1 
ATOM   571  H  HG2  . ARG A 1 38  ? 11.08400  -17.65900 9.06300  1.000 14.46555 ? 61  ARG A HG2  1 
ATOM   572  H  HG3  . ARG A 1 38  ? 9.77800   -17.99700 8.22300  1.000 14.46555 ? 61  ARG A HG3  1 
ATOM   573  H  HD2  . ARG A 1 38  ? 9.38700   -15.65200 8.03900  1.000 14.50318 ? 61  ARG A HD2  1 
ATOM   574  H  HD3  . ARG A 1 38  ? 10.81900  -15.41900 8.68900  1.000 14.50318 ? 61  ARG A HD3  1 
ATOM   575  H  HE   . ARG A 1 38  ? 10.38900  -16.01500 6.14500  1.000 15.99961 ? 61  ARG A HE   1 
ATOM   576  H  HH11 . ARG A 1 38  ? 12.79600  -16.30600 8.40900  1.000 18.32243 ? 61  ARG A HH11 1 
ATOM   577  H  HH12 . ARG A 1 38  ? 13.87800  -16.61400 7.43200  1.000 18.32243 ? 61  ARG A HH12 1 
ATOM   578  H  HH21 . ARG A 1 38  ? 12.02200  -16.55200 4.71000  1.000 20.14028 ? 61  ARG A HH21 1 
ATOM   579  H  HH22 . ARG A 1 38  ? 13.41200  -16.76300 5.20100  1.000 20.14028 ? 61  ARG A HH22 1 
ATOM   580  N  N    . ALA A 1 39  ? 8.40200   -19.37800 12.99600 1.000 11.72053 ? 62  ALA A N    1 
ATOM   581  C  CA   . ALA A 1 39  ? 7.48200   -19.28800 14.12000 1.000 11.49086 ? 62  ALA A CA   1 
ATOM   582  C  C    . ALA A 1 39  ? 8.10400   -18.67500 15.35800 1.000 10.67570 ? 62  ALA A C    1 
ATOM   583  O  O    . ALA A 1 39  ? 7.35900   -18.32200 16.27300 1.000 11.02475 ? 62  ALA A O    1 
ATOM   584  C  CB   . ALA A 1 39  ? 6.88300   -20.65100 14.42900 1.000 11.63857 ? 62  ALA A CB   1 
ATOM   585  H  H    . ALA A 1 39  ? 8.70300   -20.16700 12.83300 1.000 14.06269 ? 62  ALA A H    1 
ATOM   586  H  HA   . ALA A 1 39  ? 6.74400   -18.71100 13.86700 1.000 13.78709 ? 62  ALA A HA   1 
ATOM   587  H  HB1  . ALA A 1 39  ? 6.25900   -20.56100 15.16600 1.000 13.96433 ? 62  ALA A HB1  1 
ATOM   588  H  HB2  . ALA A 1 39  ? 6.42000   -20.97800 13.64200 1.000 13.96433 ? 62  ALA A HB2  1 
ATOM   589  H  HB3  . ALA A 1 39  ? 7.59600   -21.26200 14.67200 1.000 13.96433 ? 62  ALA A HB3  1 
ATOM   590  N  N    . ASP A 1 40  ? 9.42500   -18.52200 15.39900 1.000 11.47947 ? 63  ASP A N    1 
ATOM   591  C  CA   . ASP A 1 40  ? 10.08200  -17.84000 16.49900 1.000 11.91400 ? 63  ASP A CA   1 
ATOM   592  C  C    . ASP A 1 40  ? 10.55600  -16.44500 16.14200 1.000 12.21030 ? 63  ASP A C    1 
ATOM   593  O  O    . ASP A 1 40  ? 11.17500  -15.78800 16.97900 1.000 14.69828 ? 63  ASP A O    1 
ATOM   594  C  CB   . ASP A 1 40  ? 11.22300  -18.69300 17.03800 1.000 13.71844 ? 63  ASP A CB   1 
ATOM   595  C  CG   . ASP A 1 40  ? 10.72800  -19.99500 17.61200 1.000 13.53557 ? 63  ASP A CG   1 
ATOM   596  O  OD1  . ASP A 1 40  ? 9.80400   -19.94200 18.45300 1.000 14.21618 ? 63  ASP A OD1  1 
ATOM   597  O  OD2  . ASP A 1 40  ? 11.21800  -21.06600 17.18900 1.000 15.27473 ? 63  ASP A OD2  1 
ATOM   598  H  H    . ASP A 1 40  ? 9.96300   -18.80900 14.79300 1.000 13.77342 ? 63  ASP A H    1 
ATOM   599  H  HA   . ASP A 1 40  ? 9.44800   -17.73400 17.22600 1.000 14.29485 ? 63  ASP A HA   1 
ATOM   600  H  HB2  . ASP A 1 40  ? 11.84000  -18.89300 16.31700 1.000 16.46018 ? 63  ASP A HB2  1 
ATOM   601  H  HB3  . ASP A 1 40  ? 11.68100  -18.20600 17.74000 1.000 16.46018 ? 63  ASP A HB3  1 
ATOM   602  N  N    . GLU A 1 41  ? 10.26100  -15.96300 14.93900 1.000 11.56699 ? 64  GLU A N    1 
ATOM   603  C  CA   . GLU A 1 41  ? 10.57400  -14.58100 14.60300 1.000 11.00312 ? 64  GLU A CA   1 
ATOM   604  C  C    . GLU A 1 41  ? 9.46200   -13.65700 15.07700 1.000 11.11082 ? 64  GLU A C    1 
ATOM   605  O  O    . GLU A 1 41  ? 8.30700   -14.06400 15.22000 1.000 11.27205 ? 64  GLU A O    1 
ATOM   606  C  CB   . GLU A 1 41  ? 10.74200  -14.41300 13.09400 1.000 12.05617 ? 64  GLU A CB   1 
ATOM   607  C  CG   . GLU A 1 41  ? 11.87800  -15.24500 12.52600 1.000 12.73226 ? 64  GLU A CG   1 
ATOM   608  C  CD   . GLU A 1 41  ? 12.19200  -14.94000 11.07200 1.000 13.39562 ? 64  GLU A CD   1 
ATOM   609  O  OE1  . GLU A 1 41  ? 11.84400  -13.83900 10.58300 1.000 14.54848 ? 64  GLU A OE1  1 
ATOM   610  O  OE2  . GLU A 1 41  ? 12.80700  -15.81100 10.41100 1.000 14.45116 ? 64  GLU A OE2  1 
ATOM   611  H  H    . GLU A 1 41  ? 9.88500   -16.41100 14.30900 1.000 13.87844 ? 64  GLU A H    1 
ATOM   612  H  HA   . GLU A 1 41  ? 11.40500  -14.33200 15.03700 1.000 13.20179 ? 64  GLU A HA   1 
ATOM   613  H  HB2  . GLU A 1 41  ? 9.92200   -14.68600 12.65300 1.000 14.46546 ? 64  GLU A HB2  1 
ATOM   614  H  HB3  . GLU A 1 41  ? 10.92800  -13.48100 12.90000 1.000 14.46546 ? 64  GLU A HB3  1 
ATOM   615  H  HG2  . GLU A 1 41  ? 12.68100  -15.07300 13.04300 1.000 15.27676 ? 64  GLU A HG2  1 
ATOM   616  H  HG3  . GLU A 1 41  ? 11.63900  -16.18300 12.58600 1.000 15.27676 ? 64  GLU A HG3  1 
ATOM   617  N  N    . ARG A 1 42  ? 9.82200   -12.40200 15.31000 1.000 11.41043 ? 65  ARG A N    1 
ATOM   618  C  CA   . ARG A 1 42  ? 8.86800   -11.39900 15.73700 1.000 11.02634 ? 65  ARG A CA   1 
ATOM   619  C  C    . ARG A 1 42  ? 8.21400   -10.71500 14.54100 1.000 10.02083 ? 65  ARG A C    1 
ATOM   620  O  O    . ARG A 1 42  ? 8.87000   -10.41400 13.53400 1.000 11.37441 ? 65  ARG A O    1 
ATOM   621  C  CB   . ARG A 1 42  ? 9.55000   -10.35200 16.61600 1.000 10.95098 ? 65  ARG A CB   1 
ATOM   622  C  CG   . ARG A 1 42  ? 9.87500   -10.86900 17.99900 1.000 12.75111 ? 65  ARG A CG   1 
ATOM   623  C  CD   . ARG A 1 42  ? 10.46800  -9.80500  18.90100 1.000 13.90922 ? 65  ARG A CD   1 
ATOM   624  N  NE   . ARG A 1 42  ? 10.57500  -10.29300 20.27300 1.000 14.68811 ? 65  ARG A NE   1 
ATOM   625  C  CZ   . ARG A 1 42  ? 9.56800   -10.38000 21.13300 1.000 13.83819 ? 65  ARG A CZ   1 
ATOM   626  N  NH1  . ARG A 1 42  ? 8.35800   -9.91200  20.84800 1.000 12.65500 ? 65  ARG A NH1  1 
ATOM   627  N  NH2  . ARG A 1 42  ? 9.77600   -10.95300 22.31400 1.000 15.24889 ? 65  ARG A NH2  1 
ATOM   628  H  H    . ARG A 1 42  ? 10.62500  -12.10500 15.22500 1.000 13.69057 ? 65  ARG A H    1 
ATOM   629  H  HA   . ARG A 1 42  ? 8.16900   -11.83400 16.25000 1.000 13.22966 ? 65  ARG A HA   1 
ATOM   630  H  HB2  . ARG A 1 42  ? 10.38100  -10.08000 16.19500 1.000 13.13923 ? 65  ARG A HB2  1 
ATOM   631  H  HB3  . ARG A 1 42  ? 8.96100   -9.58800  16.71100 1.000 13.13923 ? 65  ARG A HB3  1 
ATOM   632  H  HG2  . ARG A 1 42  ? 9.06100   -11.19300 18.41400 1.000 15.29939 ? 65  ARG A HG2  1 
ATOM   633  H  HG3  . ARG A 1 42  ? 10.51900  -11.59000 17.92400 1.000 15.29939 ? 65  ARG A HG3  1 
ATOM   634  H  HD2  . ARG A 1 42  ? 11.35500  -9.57000  18.58700 1.000 16.68911 ? 65  ARG A HD2  1 
ATOM   635  H  HD3  . ARG A 1 42  ? 9.89600   -9.02100  18.89700 1.000 16.68911 ? 65  ARG A HD3  1 
ATOM   636  H  HE   . ARG A 1 42  ? 11.35200  -10.54400 20.54500 1.000 17.62379 ? 65  ARG A HE   1 
ATOM   637  H  HH11 . ARG A 1 42  ? 8.21000   -9.53900  20.08800 1.000 15.18406 ? 65  ARG A HH11 1 
ATOM   638  H  HH12 . ARG A 1 42  ? 7.72400   -9.98200  21.42400 1.000 15.18406 ? 65  ARG A HH12 1 
ATOM   639  H  HH21 . ARG A 1 42  ? 10.55500  -11.26000 22.51200 1.000 18.29671 ? 65  ARG A HH21 1 
ATOM   640  H  HH22 . ARG A 1 42  ? 9.13300   -11.01600 22.88100 1.000 18.29671 ? 65  ARG A HH22 1 
ATOM   641  N  N    . PHE A 1 43  ? 6.91600   -10.44000 14.68800 1.000 9.86557  ? 66  PHE A N    1 
ATOM   642  C  CA   . PHE A 1 43  ? 6.11300   -9.70400  13.72600 1.000 10.51089 ? 66  PHE A CA   1 
ATOM   643  C  C    . PHE A 1 43  ? 5.24600   -8.71200  14.48700 1.000 10.15587 ? 66  PHE A C    1 
ATOM   644  O  O    . PHE A 1 43  ? 4.73400   -9.02500  15.56800 1.000 9.88879  ? 66  PHE A O    1 
ATOM   645  C  CB   . PHE A 1 43  ? 5.15500   -10.63900 12.98200 1.000 10.59585 ? 66  PHE A CB   1 
ATOM   646  C  CG   . PHE A 1 43  ? 5.83500   -11.65300 12.09600 1.000 10.57579 ? 66  PHE A CG   1 
ATOM   647  C  CD1  . PHE A 1 43  ? 6.39700   -12.80900 12.62300 1.000 10.57653 ? 66  PHE A CD1  1 
ATOM   648  C  CD2  . PHE A 1 43  ? 5.88800   -11.46800 10.72900 1.000 10.94859 ? 66  PHE A CD2  1 
ATOM   649  C  CE1  . PHE A 1 43  ? 6.99300   -13.74700 11.80900 1.000 10.81621 ? 66  PHE A CE1  1 
ATOM   650  C  CE2  . PHE A 1 43  ? 6.47800   -12.41500 9.91000  1.000 11.13216 ? 66  PHE A CE2  1 
ATOM   651  C  CZ   . PHE A 1 43  ? 7.03700   -13.54800 10.45000 1.000 10.73549 ? 66  PHE A CZ   1 
ATOM   652  H  H    . PHE A 1 43  ? 6.45900   -10.68500 15.37400 1.000 11.83674 ? 66  PHE A H    1 
ATOM   653  H  HA   . PHE A 1 43  ? 6.69700   -9.24800  13.10000 1.000 12.61112 ? 66  PHE A HA   1 
ATOM   654  H  HB2  . PHE A 1 43  ? 4.62900   -11.12600 13.63500 1.000 12.71307 ? 66  PHE A HB2  1 
ATOM   655  H  HB3  . PHE A 1 43  ? 4.57400   -10.10300 12.42000 1.000 12.71307 ? 66  PHE A HB3  1 
ATOM   656  H  HD1  . PHE A 1 43  ? 6.37000   -12.95300 13.54200 1.000 12.68989 ? 66  PHE A HD1  1 
ATOM   657  H  HD2  . PHE A 1 43  ? 5.52200   -10.69900 10.35500 1.000 13.13636 ? 66  PHE A HD2  1 
ATOM   658  H  HE1  . PHE A 1 43  ? 7.36500   -14.51500 12.17800 1.000 12.97750 ? 66  PHE A HE1  1 
ATOM   659  H  HE2  . PHE A 1 43  ? 6.49700   -12.28300 8.98900  1.000 13.35664 ? 66  PHE A HE2  1 
ATOM   660  H  HZ   . PHE A 1 43  ? 7.44300   -14.17800 9.89800  1.000 12.88064 ? 66  PHE A HZ   1 
ATOM   661  N  N    . ALA A 1 44  ? 5.05700   -7.53100  13.91200 1.000 10.21362 ? 67  ALA A N    1 
ATOM   662  C  CA   . ALA A 1 44  ? 4.11800   -6.56500  14.46200 1.000 9.78196  ? 67  ALA A CA   1 
ATOM   663  C  C    . ALA A 1 44  ? 2.71200   -7.14300  14.45800 1.000 9.72267  ? 67  ALA A C    1 
ATOM   664  O  O    . ALA A 1 44  ? 2.19700   -7.53700  13.41500 1.000 11.00669 ? 67  ALA A O    1 
ATOM   665  C  CB   . ALA A 1 44  ? 4.16200   -5.27800  13.64000 1.000 10.53162 ? 67  ALA A CB   1 
ATOM   666  H  H    . ALA A 1 44  ? 5.46100   -7.26400  13.20100 1.000 12.25439 ? 67  ALA A H    1 
ATOM   667  H  HA   . ALA A 1 44  ? 4.36500   -6.35700  15.37700 1.000 11.73640 ? 67  ALA A HA   1 
ATOM   668  H  HB1  . ALA A 1 44  ? 3.54400   -4.63600  14.02400 1.000 12.63599 ? 67  ALA A HB1  1 
ATOM   669  H  HB2  . ALA A 1 44  ? 5.06400   -4.92100  13.66000 1.000 12.63599 ? 67  ALA A HB2  1 
ATOM   670  H  HB3  . ALA A 1 44  ? 3.90600   -5.47800  12.72600 1.000 12.63599 ? 67  ALA A HB3  1 
ATOM   671  N  N    . MET A 1 45  ? 2.08400   -7.17700  15.64100 1.000 9.42750  ? 68  MET A N    1 
ATOM   672  C  CA   . MET A 1 45  ? 0.77100   -7.79300  15.78400 1.000 9.43955  ? 68  MET A CA   1 
ATOM   673  C  C    . MET A 1 45  ? -0.33800  -6.98800  15.12700 1.000 9.11997  ? 68  MET A C    1 
ATOM   674  O  O    . MET A 1 45  ? -1.35000  -7.57400  14.71000 1.000 9.44056  ? 68  MET A O    1 
ATOM   675  C  CB   . MET A 1 45  ? 0.41600   -7.92500  17.26600 1.000 9.81865  ? 68  MET A CB   1 
ATOM   676  C  CG   . MET A 1 45  ? 1.25700   -8.95500  17.98700 1.000 10.30346 ? 68  MET A CG   1 
ATOM   677  S  SD   . MET A 1 45  ? 0.86100   -9.09900  19.73900 1.000 10.52101 ? 68  MET A SD   1 
ATOM   678  C  CE   . MET A 1 45  ? 1.65600   -7.61900  20.36800 1.000 10.90996 ? 68  MET A CE   1 
ATOM   679  H  H    . MET A 1 45  ? 2.40000   -6.85000  16.37100 1.000 11.31105 ? 68  MET A H    1 
ATOM   680  H  HA   . MET A 1 45  ? 0.83000   -8.66800  15.36900 1.000 11.32552 ? 68  MET A HA   1 
ATOM   681  H  HB2  . MET A 1 45  ? 0.55500   -7.06900  17.70000 1.000 11.78043 ? 68  MET A HB2  1 
ATOM   682  H  HB3  . MET A 1 45  ? -0.51400  -8.19000  17.34500 1.000 11.78043 ? 68  MET A HB3  1 
ATOM   683  H  HG2  . MET A 1 45  ? 1.11200   -9.82200  17.57600 1.000 12.36221 ? 68  MET A HG2  1 
ATOM   684  H  HG3  . MET A 1 45  ? 2.19100   -8.70500  17.91300 1.000 12.36221 ? 68  MET A HG3  1 
ATOM   685  H  HE1  . MET A 1 45  ? 1.62600   -7.63200  21.33700 1.000 13.09001 ? 68  MET A HE1  1 
ATOM   686  H  HE2  . MET A 1 45  ? 2.57800   -7.60400  20.06600 1.000 13.09001 ? 68  MET A HE2  1 
ATOM   687  H  HE3  . MET A 1 45  ? 1.18500   -6.84100  20.03300 1.000 13.09001 ? 68  MET A HE3  1 
ATOM   688  N  N    . CYS A 1 46  ? -0.21400  -5.66600  15.13400 1.000 10.09387 ? 69  CYS A N    1 
ATOM   689  C  CA   . CYS A 1 46  ? -1.30400  -4.78600  14.74500 1.000 9.39392  ? 69  CYS A CA   1 
ATOM   690  C  C    . CYS A 1 46  ? -2.56500  -5.20000  15.49600 1.000 9.39114  ? 69  CYS A C    1 
ATOM   691  O  O    . CYS A 1 46  ? -2.48600  -5.53800  16.68300 1.000 9.99624  ? 69  CYS A O    1 
ATOM   692  C  CB   . CYS A 1 46  ? -1.43500  -4.70500  13.22300 1.000 10.21318 ? 69  CYS A CB   1 
ATOM   693  S  SG   . CYS A 1 46  ? 0.11400   -4.17900  12.43300 1.000 11.51098 ? 69  CYS A SG   1 
ATOM   694  H  H    . CYS A 1 46  ? 0.50200   -5.25000  15.36400 1.000 12.11070 ? 69  CYS A H    1 
ATOM   695  H  HA   . CYS A 1 46  ? -1.13400  -3.86500  14.99700 1.000 11.27076 ? 69  CYS A HA   1 
ATOM   696  H  HB2  . CYS A 1 46  ? -1.67100  -5.58000  12.87700 1.000 12.25386 ? 69  CYS A HB2  1 
ATOM   697  H  HB3  . CYS A 1 46  ? -2.12500  -4.06100  12.99700 1.000 12.25386 ? 69  CYS A HB3  1 
ATOM   698  H  HG   . CYS A 1 46  ? 0.02200   -4.34200  11.24800 1.000 13.81123 ? 69  CYS A HG   1 
ATOM   699  N  N    . SER A 1 47  ? -3.72700  -5.21500  14.84000 1.000 9.40351  ? 70  SER A N    1 
ATOM   700  C  CA   . SER A 1 47  ? -4.97300  -5.41600  15.57000 1.000 9.76181  ? 70  SER A CA   1 
ATOM   701  C  C    . SER A 1 47  ? -5.14700  -6.83200  16.11300 1.000 9.36365  ? 70  SER A C    1 
ATOM   702  O  O    . SER A 1 47  ? -6.08800  -7.05500  16.88600 1.000 10.04167 ? 70  SER A O    1 
ATOM   703  C  CB   . SER A 1 47  ? -6.19300  -5.02900  14.74400 1.000 10.20770 ? 70  SER A CB   1 
ATOM   704  O  OG   . SER A 1 47  ? -6.18400  -3.63400  14.47900 1.000 11.65719 ? 70  SER A OG   1 
ATOM   705  H  H    . SER A 1 47  ? -3.81600  -5.11500  13.99100 1.000 11.28227 ? 70  SER A H    1 
ATOM   706  H  HA   . SER A 1 47  ? -4.94700  -4.80900  16.32700 1.000 11.71223 ? 70  SER A HA   1 
ATOM   707  H  HB2  . SER A 1 47  ? -6.17400  -5.51200  13.90300 1.000 12.24730 ? 70  SER A HB2  1 
ATOM   708  H  HB3  . SER A 1 47  ? -6.99700  -5.25400  15.23800 1.000 12.24730 ? 70  SER A HB3  1 
ATOM   709  N  N    . THR A 1 48  ? -4.26300  -7.77700  15.78300 1.000 9.60587  ? 71  THR A N    1 
ATOM   710  C  CA   . THR A 1 48  ? -4.38100  -9.07700  16.44500 1.000 9.54724  ? 71  THR A CA   1 
ATOM   711  C  C    . THR A 1 48  ? -4.11500  -8.97000  17.94300 1.000 9.43740  ? 71  THR A C    1 
ATOM   712  O  O    . THR A 1 48  ? -4.56400  -9.84000  18.69200 1.000 10.19831 ? 71  THR A O    1 
ATOM   713  C  CB   . THR A 1 48  ? -3.49100  -10.17000 15.81900 1.000 9.42856  ? 71  THR A CB   1 
ATOM   714  O  OG1  . THR A 1 48  ? -2.09200  -9.92400  16.03000 1.000 9.64879  ? 71  THR A OG1  1 
ATOM   715  C  CG2  . THR A 1 48  ? -3.81500  -10.32000 14.33300 1.000 9.18950  ? 71  THR A CG2  1 
ATOM   716  H  H    . THR A 1 48  ? -3.62500  -7.69600  15.21200 1.000 11.52510 ? 71  THR A H    1 
ATOM   717  H  HA   . THR A 1 48  ? -5.28900  -9.38600  16.30100 1.000 11.45474 ? 71  THR A HA   1 
ATOM   718  H  HB   . THR A 1 48  ? -3.68000  -11.01400 16.25700 1.000 11.31232 ? 71  THR A HB   1 
ATOM   719  H  HG1  . THR A 1 48  ? -1.87200  -9.19400  15.67800 1.000 11.57660 ? 71  THR A HG1  1 
ATOM   720  H  HG21 . THR A 1 48  ? -3.30500  -11.05400 13.95500 1.000 11.02545 ? 71  THR A HG21 1 
ATOM   721  H  HG22 . THR A 1 48  ? -4.76100  -10.50000 14.21600 1.000 11.02545 ? 71  THR A HG22 1 
ATOM   722  H  HG23 . THR A 1 48  ? -3.58900  -9.50400  13.86000 1.000 11.02545 ? 71  THR A HG23 1 
ATOM   723  N  N    . SER A 1 49  ? -3.44200  -7.90000  18.37900 1.000 9.41882  ? 72  SER A N    1 
ATOM   724  C  CA   . SER A 1 49  ? -3.24600  -7.65000  19.80200 1.000 9.96126  ? 72  SER A CA   1 
ATOM   725  C  C    . SER A 1 49  ? -4.54100  -7.37700  20.55300 1.000 9.52337  ? 72  SER A C    1 
ATOM   726  O  O    . SER A 1 49  ? -4.54900  -7.44300  21.78900 1.000 9.92435  ? 72  SER A O    1 
ATOM   727  C  CB   . SER A 1 49  ? -2.28400  -6.47700  19.97600 1.000 9.90562  ? 72  SER A CB   1 
ATOM   728  O  OG   . SER A 1 49  ? -2.84300  -5.25800  19.49700 1.000 10.37237 ? 72  SER A OG   1 
ATOM   729  H  H    . SER A 1 49  ? -3.08900  -7.30600  17.86800 1.000 11.30063 ? 72  SER A H    1 
ATOM   730  H  HA   . SER A 1 49  ? -2.85400  -8.44200  20.20100 1.000 11.95156 ? 72  SER A HA   1 
ATOM   731  H  HB2  . SER A 1 49  ? -2.08200  -6.37700  20.91900 1.000 11.88479 ? 72  SER A HB2  1 
ATOM   732  H  HB3  . SER A 1 49  ? -1.47200  -6.66300  19.48000 1.000 11.88479 ? 72  SER A HB3  1 
ATOM   733  H  HG   . SER A 1 49  ? -3.11900  -5.35800  18.71000 1.000 12.44490 ? 72  SER A HG   1 
ATOM   734  N  N    . LYS A 1 50  ? -5.63000  -7.06100  19.84900 1.000 9.60882  ? 73  LYS A N    1 
ATOM   735  C  CA   . LYS A 1 50  ? -6.90000  -6.79100  20.51200 1.000 9.83583  ? 73  LYS A CA   1 
ATOM   736  C  C    . LYS A 1 50  ? -7.42500  -8.01100  21.25300 1.000 9.63087  ? 73  LYS A C    1 
ATOM   737  O  O    . LYS A 1 50  ? -8.16400  -7.86900  22.22600 1.000 10.17779 ? 73  LYS A O    1 
ATOM   738  C  CB   . LYS A 1 50  ? -7.90800  -6.25500  19.49200 1.000 9.44399  ? 73  LYS A CB   1 
ATOM   739  C  CG   . LYS A 1 50  ? -7.49900  -4.86300  18.99300 1.000 10.63441 ? 73  LYS A CG   1 
ATOM   740  C  CD   . LYS A 1 50  ? -8.32400  -4.30300  17.84200 1.000 11.29875 ? 73  LYS A CD   1 
ATOM   741  C  CE   . LYS A 1 50  ? -7.78200  -2.92400  17.43500 1.000 12.39914 ? 73  LYS A CE   1 
ATOM   742  N  NZ   . LYS A 1 50  ? -8.18200  -2.40100  16.11700 1.000 14.50866 ? 73  LYS A NZ   1 
ATOM   743  H  H    . LYS A 1 50  ? -5.65700  -6.99600  18.99200 1.000 11.52864 ? 73  LYS A H    1 
ATOM   744  H  HA   . LYS A 1 50  ? -6.77700  -6.10000  21.18200 1.000 11.80104 ? 73  LYS A HA   1 
ATOM   745  H  HB2  . LYS A 1 50  ? -7.94600  -6.85500  18.73100 1.000 11.33084 ? 73  LYS A HB2  1 
ATOM   746  H  HB3  . LYS A 1 50  ? -8.78200  -6.18900  19.90700 1.000 11.33084 ? 73  LYS A HB3  1 
ATOM   747  H  HG2  . LYS A 1 50  ? -7.57700  -4.23900  19.73200 1.000 12.75934 ? 73  LYS A HG2  1 
ATOM   748  H  HG3  . LYS A 1 50  ? -6.57800  -4.90500  18.69200 1.000 12.75934 ? 73  LYS A HG3  1 
ATOM   749  H  HD2  . LYS A 1 50  ? -8.26800  -4.89900  17.07800 1.000 13.55655 ? 73  LYS A HD2  1 
ATOM   750  H  HD3  . LYS A 1 50  ? -9.24900  -4.20600  18.11900 1.000 13.55655 ? 73  LYS A HD3  1 
ATOM   751  H  HE2  . LYS A 1 50  ? -8.08200  -2.27900  18.09500 1.000 14.87702 ? 73  LYS A HE2  1 
ATOM   752  H  HE3  . LYS A 1 50  ? -6.81300  -2.97200  17.43500 1.000 14.87702 ? 73  LYS A HE3  1 
ATOM   753  H  HZ1  . LYS A 1 50  ? -9.01700  -2.64700  15.93200 1.000 17.40844 ? 73  LYS A HZ1  1 
ATOM   754  H  HZ2  . LYS A 1 50  ? -8.13600  -1.51200  16.11600 1.000 17.40844 ? 73  LYS A HZ2  1 
ATOM   755  H  HZ3  . LYS A 1 50  ? -7.64000  -2.71800  15.48600 1.000 17.40844 ? 73  LYS A HZ3  1 
ATOM   756  N  N    . VAL A 1 51  ? -7.06200  -9.21600  20.81100 1.000 9.75270  ? 74  VAL A N    1 
ATOM   757  C  CA   . VAL A 1 51  ? -7.44600  -10.42100 21.54700 1.000 10.01579 ? 74  VAL A CA   1 
ATOM   758  C  C    . VAL A 1 51  ? -6.87600  -10.40000 22.95900 1.000 9.75183  ? 74  VAL A C    1 
ATOM   759  O  O    . VAL A 1 51  ? -7.59100  -10.69100 23.92400 1.000 9.70717  ? 74  VAL A O    1 
ATOM   760  C  CB   . VAL A 1 51  ? -7.05900  -11.69700 20.78000 1.000 10.35558 ? 74  VAL A CB   1 
ATOM   761  C  CG1  . VAL A 1 51  ? -7.22900  -12.93400 21.65300 1.000 10.98987 ? 74  VAL A CG1  1 
ATOM   762  C  CG2  . VAL A 1 51  ? -7.91600  -11.80000 19.52100 1.000 11.22866 ? 74  VAL A CG2  1 
ATOM   763  H  H    . VAL A 1 51  ? -6.60100  -9.36200  20.10000 1.000 11.70129 ? 74  VAL A H    1 
ATOM   764  H  HA   . VAL A 1 51  ? -8.41300  -10.42200 21.62500 1.000 12.01700 ? 74  VAL A HA   1 
ATOM   765  H  HB   . VAL A 1 51  ? -6.12400  -11.65300 20.52800 1.000 12.42475 ? 74  VAL A HB   1 
ATOM   766  H  HG11 . VAL A 1 51  ? -7.03000  -13.72300 21.12500 1.000 13.18590 ? 74  VAL A HG11 1 
ATOM   767  H  HG12 . VAL A 1 51  ? -6.61700  -12.87700 22.40400 1.000 13.18590 ? 74  VAL A HG12 1 
ATOM   768  H  HG13 . VAL A 1 51  ? -8.14300  -12.97200 21.97300 1.000 13.18590 ? 74  VAL A HG13 1 
ATOM   769  H  HG21 . VAL A 1 51  ? -7.63900  -12.57900 19.01400 1.000 13.47245 ? 74  VAL A HG21 1 
ATOM   770  H  HG22 . VAL A 1 51  ? -8.84700  -11.88600 19.77900 1.000 13.47245 ? 74  VAL A HG22 1 
ATOM   771  H  HG23 . VAL A 1 51  ? -7.79300  -10.99800 18.99000 1.000 13.47245 ? 74  VAL A HG23 1 
ATOM   772  N  N    A MET A 1 52  ? -5.59000  -10.06300 23.10300 0.273 9.86560  ? 75  MET A N    1 
ATOM   773  N  N    B MET A 1 52  ? -5.59100  -10.06000 23.10100 0.727 10.62420 ? 75  MET A N    1 
ATOM   774  C  CA   A MET A 1 52  ? -4.97900  -10.04800 24.43200 0.273 9.69509  ? 75  MET A CA   1 
ATOM   775  C  CA   B MET A 1 52  ? -4.98100  -10.06200 24.43000 0.727 10.74060 ? 75  MET A CA   1 
ATOM   776  C  C    A MET A 1 52  ? -5.62100  -8.99100  25.32000 0.273 9.69080  ? 75  MET A C    1 
ATOM   777  C  C    B MET A 1 52  ? -5.59400  -8.98800  25.32500 0.727 10.34882 ? 75  MET A C    1 
ATOM   778  O  O    A MET A 1 52  ? -5.85500  -9.22800  26.51100 0.273 9.52258  ? 75  MET A O    1 
ATOM   779  O  O    B MET A 1 52  ? -5.78000  -9.21000  26.52800 0.727 11.23062 ? 75  MET A O    1 
ATOM   780  C  CB   A MET A 1 52  ? -3.46900  -9.81700  24.32300 0.273 9.33000  ? 75  MET A CB   1 
ATOM   781  C  CB   B MET A 1 52  ? -3.46400  -9.90500  24.33200 0.727 11.18681 ? 75  MET A CB   1 
ATOM   782  C  CG   A MET A 1 52  ? -2.66500  -10.07000 25.62000 0.273 9.77728  ? 75  MET A CG   1 
ATOM   783  C  CG   B MET A 1 52  ? -2.72200  -10.32300 25.60700 0.727 13.75161 ? 75  MET A CG   1 
ATOM   784  S  SD   A MET A 1 52  ? -2.67700  -11.77300 26.24800 0.273 10.70223 ? 75  MET A SD   1 
ATOM   785  S  SD   B MET A 1 52  ? -2.59700  -12.11900 25.80400 0.727 15.13755 ? 75  MET A SD   1 
ATOM   786  C  CE   A MET A 1 52  ? -3.06400  -12.68500 24.74400 0.273 9.54593  ? 75  MET A CE   1 
ATOM   787  C  CE   B MET A 1 52  ? -1.17600  -12.42400 24.80400 0.727 14.82550 ? 75  MET A CE   1 
ATOM   788  H  H    A MET A 1 52  ? -5.06100  -9.84400  22.46100 0.273 11.83677 ? 75  MET A H    1 
ATOM   789  H  H    B MET A 1 52  ? -5.06600  -9.83000  22.46000 0.727 12.74709 ? 75  MET A H    1 
ATOM   790  H  HA   A MET A 1 52  ? -5.11000  -10.91900 24.83800 0.273 11.63216 ? 75  MET A HA   1 
ATOM   791  H  HA   B MET A 1 52  ? -5.14600  -10.92700 24.83600 0.727 12.88677 ? 75  MET A HA   1 
ATOM   792  H  HB2  A MET A 1 52  ? -3.11700  -10.41300 23.64300 0.273 11.19405 ? 75  MET A HB2  1 
ATOM   793  H  HB2  B MET A 1 52  ? -3.13800  -10.45800 23.60400 0.727 13.42223 ? 75  MET A HB2  1 
ATOM   794  H  HB3  A MET A 1 52  ? -3.31900  -8.89400  24.06500 0.273 11.19405 ? 75  MET A HB3  1 
ATOM   795  H  HB3  B MET A 1 52  ? -3.25600  -8.97400  24.15900 0.727 13.42223 ? 75  MET A HB3  1 
ATOM   796  H  HG2  A MET A 1 52  ? -1.73900  -9.83300  25.45400 0.273 11.73078 ? 75  MET A HG2  1 
ATOM   797  H  HG2  B MET A 1 52  ? -1.82100  -9.96300  25.57900 0.727 16.49998 ? 75  MET A HG2  1 
ATOM   798  H  HG3  A MET A 1 52  ? -3.03200  -9.50600  26.31900 0.273 11.73078 ? 75  MET A HG3  1 
ATOM   799  H  HG3  B MET A 1 52  ? -3.19600  -9.97100  26.37600 0.727 16.49998 ? 75  MET A HG3  1 
ATOM   800  H  HE1  A MET A 1 52  ? -2.94700  -13.63300 24.91100 0.273 11.45317 ? 75  MET A HE1  1 
ATOM   801  H  HE1  B MET A 1 52  ? -0.77000  -13.26100 25.08000 0.727 17.78865 ? 75  MET A HE1  1 
ATOM   802  H  HE2  A MET A 1 52  ? -3.98300  -12.50400 24.49300 0.273 11.45317 ? 75  MET A HE2  1 
ATOM   803  H  HE2  B MET A 1 52  ? -1.44900  -12.48000 23.87500 0.727 17.78865 ? 75  MET A HE2  1 
ATOM   804  H  HE3  A MET A 1 52  ? -2.46500  -12.39700 24.03700 0.273 11.45317 ? 75  MET A HE3  1 
ATOM   805  H  HE3  B MET A 1 52  ? -0.54500  -11.69600 24.92000 0.727 17.78865 ? 75  MET A HE3  1 
ATOM   806  N  N    . ALA A 1 53  ? -5.91600  -7.81500  24.75900 1.000 10.29864 ? 76  ALA A N    1 
ATOM   807  C  CA   . ALA A 1 53  ? -6.54500  -6.75700  25.55300 1.000 10.54349 ? 76  ALA A CA   1 
ATOM   808  C  C    . ALA A 1 53  ? -7.93200  -7.16800  26.02900 1.000 10.35808 ? 76  ALA A C    1 
ATOM   809  O  O    . ALA A 1 53  ? -8.28300  -6.96300  27.19900 1.000 10.91657 ? 76  ALA A O    1 
ATOM   810  C  CB   . ALA A 1 53  ? -6.59000  -5.45800  24.74800 1.000 11.30802 ? 76  ALA A CB   1 
ATOM   811  H  H    A ALA A 1 53  ? -5.76700  -7.60900  23.93700 0.273 12.35642 ? 76  ALA A H    1 
ATOM   812  H  H    B ALA A 1 53  ? -5.78400  -7.61400  23.93300 0.727 12.35642 ? 76  ALA A H    1 
ATOM   813  H  HA   . ALA A 1 53  ? -6.00700  -6.59400  26.34300 1.000 12.65024 ? 76  ALA A HA   1 
ATOM   814  H  HB1  . ALA A 1 53  ? -7.02300  -4.77200  25.27900 1.000 13.56767 ? 76  ALA A HB1  1 
ATOM   815  H  HB2  . ALA A 1 53  ? -5.68300  -5.18800  24.53400 1.000 13.56767 ? 76  ALA A HB2  1 
ATOM   816  H  HB3  . ALA A 1 53  ? -7.09100  -5.61000  23.93100 1.000 13.56767 ? 76  ALA A HB3  1 
ATOM   817  N  N    . ALA A 1 54  ? -8.73900  -7.74800  25.13600 1.000 10.16163 ? 77  ALA A N    1 
ATOM   818  C  CA   . ALA A 1 54  ? -10.06700 -8.19300  25.54300 1.000 9.96741  ? 77  ALA A CA   1 
ATOM   819  C  C    . ALA A 1 54  ? -9.96800  -9.30700  26.57300 1.000 9.67195  ? 77  ALA A C    1 
ATOM   820  O  O    . ALA A 1 54  ? -10.74800 -9.34200  27.53400 1.000 10.43751 ? 77  ALA A O    1 
ATOM   821  C  CB   . ALA A 1 54  ? -10.87300 -8.65200  24.32900 1.000 10.77669 ? 77  ALA A CB   1 
ATOM   822  H  H    . ALA A 1 54  ? -8.54400  -7.89000  24.31100 1.000 12.19200 ? 77  ALA A H    1 
ATOM   823  H  HA   . ALA A 1 54  ? -10.54000 -7.44600  25.94100 1.000 11.95894 ? 77  ALA A HA   1 
ATOM   824  H  HB1  . ALA A 1 54  ? -11.73600 -8.98000  24.62800 1.000 12.93008 ? 77  ALA A HB1  1 
ATOM   825  H  HB2  . ALA A 1 54  ? -10.99500 -7.90000  23.72900 1.000 12.93008 ? 77  ALA A HB2  1 
ATOM   826  H  HB3  . ALA A 1 54  ? -10.38900 -9.36100  23.87700 1.000 12.93008 ? 77  ALA A HB3  1 
ATOM   827  N  N    . ALA A 1 55  ? -9.01200  -10.22100 26.38700 1.000 9.60925  ? 78  ALA A N    1 
ATOM   828  C  CA   . ALA A 1 55  ? -8.83200  -11.29900 27.34800 1.000 9.92337  ? 78  ALA A CA   1 
ATOM   829  C  C    . ALA A 1 55  ? -8.42200  -10.76100 28.71700 1.000 9.93954  ? 78  ALA A C    1 
ATOM   830  O  O    . ALA A 1 55  ? -8.84300  -11.30000 29.74400 1.000 10.37086 ? 78  ALA A O    1 
ATOM   831  C  CB   . ALA A 1 55  ? -7.80000  -12.29300 26.83100 1.000 10.99791 ? 78  ALA A CB   1 
ATOM   832  H  H    . ALA A 1 55  ? -8.46500  -10.23500 25.72400 1.000 11.52915 ? 78  ALA A H    1 
ATOM   833  H  HA   . ALA A 1 55  ? -9.67500  -11.76800 27.45200 1.000 11.90609 ? 78  ALA A HA   1 
ATOM   834  H  HB1  . ALA A 1 55  ? -7.69100  -13.00300 27.48300 1.000 13.19554 ? 78  ALA A HB1  1 
ATOM   835  H  HB2  . ALA A 1 55  ? -8.11000  -12.66200 25.98900 1.000 13.19554 ? 78  ALA A HB2  1 
ATOM   836  H  HB3  . ALA A 1 55  ? -6.95600  -11.83300 26.69900 1.000 13.19554 ? 78  ALA A HB3  1 
ATOM   837  N  N    . ALA A 1 56  ? -7.60400  -9.70600  28.75700 1.000 10.02865 ? 79  ALA A N    1 
ATOM   838  C  CA   . ALA A 1 56  ? -7.20200  -9.13400  30.04000 1.000 10.75129 ? 79  ALA A CA   1 
ATOM   839  C  C    . ALA A 1 56  ? -8.41100  -8.56600  30.77100 1.000 10.50368 ? 79  ALA A C    1 
ATOM   840  O  O    . ALA A 1 56  ? -8.54300  -8.72000  31.98800 1.000 12.09904 ? 79  ALA A O    1 
ATOM   841  C  CB   . ALA A 1 56  ? -6.13900  -8.06200  29.82200 1.000 11.19246 ? 79  ALA A CB   1 
ATOM   842  H  H    . ALA A 1 56  ? -7.27400  -9.31100  28.06700 1.000 12.03243 ? 79  ALA A H    1 
ATOM   843  H  HA   . ALA A 1 56  ? -6.81000  -9.82500  30.59600 1.000 12.89960 ? 79  ALA A HA   1 
ATOM   844  H  HB1  . ALA A 1 56  ? -5.90400  -7.67200  30.67900 1.000 13.42901 ? 79  ALA A HB1  1 
ATOM   845  H  HB2  . ALA A 1 56  ? -5.35700  -8.47100  29.41900 1.000 13.42901 ? 79  ALA A HB2  1 
ATOM   846  H  HB3  . ALA A 1 56  ? -6.49600  -7.37900  29.23400 1.000 13.42901 ? 79  ALA A HB3  1 
ATOM   847  N  N    . VAL A 1 57  ? -9.30800  -7.90500  30.04500 1.000 10.41072 ? 80  VAL A N    1 
ATOM   848  C  CA   . VAL A 1 57  ? -10.55200 -7.41000  30.63700 1.000 11.40783 ? 80  VAL A CA   1 
ATOM   849  C  C    . VAL A 1 57  ? -11.41800 -8.56700  31.13000 1.000 11.05604 ? 80  VAL A C    1 
ATOM   850  O  O    . VAL A 1 57  ? -11.97600 -8.51700  32.23100 1.000 12.20837 ? 80  VAL A O    1 
ATOM   851  C  CB   . VAL A 1 57  ? -11.29000 -6.48200  29.65100 1.000 12.27367 ? 80  VAL A CB   1 
ATOM   852  C  CG1  . VAL A 1 57  ? -12.69100 -6.13700  30.14800 1.000 13.27902 ? 80  VAL A CG1  1 
ATOM   853  C  CG2  . VAL A 1 57  ? -10.48500 -5.20400  29.42700 1.000 13.95011 ? 80  VAL A CG2  1 
ATOM   854  H  H    . VAL A 1 57  ? -9.22300  -7.72800  29.20700 1.000 12.49092 ? 80  VAL A H    1 
ATOM   855  H  HA   . VAL A 1 57  ? -10.33000 -6.87500  31.41500 1.000 13.68745 ? 80  VAL A HA   1 
ATOM   856  H  HB   . VAL A 1 57  ? -11.38400 -6.95200  28.80800 1.000 14.72646 ? 80  VAL A HB   1 
ATOM   857  H  HG11 . VAL A 1 57  ? -13.04500 -5.40900  29.61300 1.000 15.93288 ? 80  VAL A HG11 1 
ATOM   858  H  HG12 . VAL A 1 57  ? -13.25900 -6.91900  30.05900 1.000 15.93288 ? 80  VAL A HG12 1 
ATOM   859  H  HG13 . VAL A 1 57  ? -12.63900 -5.87000  31.07900 1.000 15.93288 ? 80  VAL A HG13 1 
ATOM   860  H  HG21 . VAL A 1 57  ? -10.95000 -4.64800  28.78300 1.000 16.73818 ? 80  VAL A HG21 1 
ATOM   861  H  HG22 . VAL A 1 57  ? -10.39900 -4.73300  30.27000 1.000 16.73818 ? 80  VAL A HG22 1 
ATOM   862  H  HG23 . VAL A 1 57  ? -9.60700  -5.44000  29.08800 1.000 16.73818 ? 80  VAL A HG23 1 
ATOM   863  N  N    . LEU A 1 58  ? -11.55100 -9.61800  30.31800 1.000 10.68055 ? 81  LEU A N    1 
ATOM   864  C  CA   . LEU A 1 58  ? -12.30800 -10.79100 30.73900 1.000 11.14080 ? 81  LEU A CA   1 
ATOM   865  C  C    . LEU A 1 58  ? -11.72400 -11.39300 32.01200 1.000 11.71187 ? 81  LEU A C    1 
ATOM   866  O  O    . LEU A 1 58  ? -12.46800 -11.74700 32.93300 1.000 12.49429 ? 81  LEU A O    1 
ATOM   867  C  CB   . LEU A 1 58  ? -12.35300 -11.82800 29.61500 1.000 11.30165 ? 81  LEU A CB   1 
ATOM   868  C  CG   . LEU A 1 58  ? -13.31600 -11.51100 28.47100 1.000 11.20996 ? 81  LEU A CG   1 
ATOM   869  C  CD1  . LEU A 1 58  ? -13.09200 -12.45300 27.30700 1.000 11.25944 ? 81  LEU A CD1  1 
ATOM   870  C  CD2  . LEU A 1 58  ? -14.77400 -11.57700 28.92800 1.000 12.55212 ? 81  LEU A CD2  1 
ATOM   871  H  H    . LEU A 1 58  ? -11.21700 -9.67400  29.52800 1.000 12.81471 ? 81  LEU A H    1 
ATOM   872  H  HA   . LEU A 1 58  ? -13.22200 -10.52300 30.92600 1.000 13.36701 ? 81  LEU A HA   1 
ATOM   873  H  HB2  . LEU A 1 58  ? -11.46400 -11.90300 29.23400 1.000 13.56003 ? 81  LEU A HB2  1 
ATOM   874  H  HB3  . LEU A 1 58  ? -12.62300 -12.67800 29.99500 1.000 13.56003 ? 81  LEU A HB3  1 
ATOM   875  H  HG   . LEU A 1 58  ? -13.14100 -10.60400 28.17500 1.000 13.45000 ? 81  LEU A HG   1 
ATOM   876  H  HD11 . LEU A 1 58  ? -13.73200 -12.24900 26.60800 1.000 13.50938 ? 81  LEU A HD11 1 
ATOM   877  H  HD12 . LEU A 1 58  ? -12.18900 -12.33300 26.97400 1.000 13.50938 ? 81  LEU A HD12 1 
ATOM   878  H  HD13 . LEU A 1 58  ? -13.21400 -13.36600 27.61100 1.000 13.50938 ? 81  LEU A HD13 1 
ATOM   879  H  HD21 . LEU A 1 58  ? -15.35200 -11.42500 28.16300 1.000 15.06059 ? 81  LEU A HD21 1 
ATOM   880  H  HD22 . LEU A 1 58  ? -14.94800 -12.45400 29.30400 1.000 15.06059 ? 81  LEU A HD22 1 
ATOM   881  H  HD23 . LEU A 1 58  ? -14.92700 -10.89300 29.59800 1.000 15.06059 ? 81  LEU A HD23 1 
ATOM   882  N  N    B LYS A 1 59  ? -10.39800 -11.51100 32.09000 0.842 11.60161 ? 82  LYS A N    1 
ATOM   883  N  N    C LYS A 1 59  ? -10.39700 -11.50800 32.08900 0.158 12.01909 ? 82  LYS A N    1 
ATOM   884  C  CA   B LYS A 1 59  ? -9.77200  -12.03100 33.30500 0.842 12.57405 ? 82  LYS A CA   1 
ATOM   885  C  CA   C LYS A 1 59  ? -9.77600  -12.02800 33.30300 0.158 12.54461 ? 82  LYS A CA   1 
ATOM   886  C  C    B LYS A 1 59  ? -10.09700 -11.14200 34.49900 0.842 13.17818 ? 82  LYS A C    1 
ATOM   887  C  C    C LYS A 1 59  ? -10.10400 -11.14100 34.49900 0.158 12.74317 ? 82  LYS A C    1 
ATOM   888  O  O    B LYS A 1 59  ? -10.45400 -11.64000 35.57500 0.842 14.70808 ? 82  LYS A O    1 
ATOM   889  O  O    C LYS A 1 59  ? -10.45600 -11.63600 35.57700 0.158 13.12974 ? 82  LYS A O    1 
ATOM   890  C  CB   B LYS A 1 59  ? -8.25800  -12.14600 33.11500 0.842 13.57440 ? 82  LYS A CB   1 
ATOM   891  C  CB   C LYS A 1 59  ? -8.26300  -12.13800 33.11000 0.158 12.99387 ? 82  LYS A CB   1 
ATOM   892  C  CG   B LYS A 1 59  ? -7.49400  -12.60800 34.36000 0.842 16.22354 ? 82  LYS A CG   1 
ATOM   893  C  CG   C LYS A 1 59  ? -7.51700  -12.69500 34.31600 0.158 13.80895 ? 82  LYS A CG   1 
ATOM   894  C  CD   B LYS A 1 59  ? -7.88800  -14.00600 34.78700 0.842 20.37927 ? 82  LYS A CD   1 
ATOM   895  C  CD   C LYS A 1 59  ? -7.94800  -14.11900 34.63200 0.158 15.15323 ? 82  LYS A CD   1 
ATOM   896  C  CE   B LYS A 1 59  ? -7.07400  -14.46900 35.98600 0.842 24.37373 ? 82  LYS A CE   1 
ATOM   897  C  CE   C LYS A 1 59  ? -7.19800  -14.67500 35.83000 0.158 16.30273 ? 82  LYS A CE   1 
ATOM   898  N  NZ   B LYS A 1 59  ? -7.44000  -15.84000 36.41600 0.842 26.32452 ? 82  LYS A NZ   1 
ATOM   899  N  NZ   C LYS A 1 59  ? -5.72700  -14.65000 35.62400 0.158 16.91821 ? 82  LYS A NZ   1 
ATOM   900  H  H    B LYS A 1 59  ? -9.84600  -11.30100 31.46400 0.842 13.91998 ? 82  LYS A H    1 
ATOM   901  H  H    C LYS A 1 59  ? -9.84600  -11.29600 31.46300 0.158 14.42096 ? 82  LYS A H    1 
ATOM   902  H  HA   B LYS A 1 59  ? -10.11400 -12.92100 33.48200 0.842 15.08692 ? 82  LYS A HA   1 
ATOM   903  H  HA   C LYS A 1 59  ? -10.12000 -12.91700 33.48000 0.158 15.05159 ? 82  LYS A HA   1 
ATOM   904  H  HB2  B LYS A 1 59  ? -8.08300  -12.78800 32.40900 0.842 16.28733 ? 82  LYS A HB2  1 
ATOM   905  H  HB2  C LYS A 1 59  ? -8.08800  -12.72600 32.35900 0.158 15.59069 ? 82  LYS A HB2  1 
ATOM   906  H  HB3  B LYS A 1 59  ? -7.91100  -11.27500 32.86500 0.842 16.28733 ? 82  LYS A HB3  1 
ATOM   907  H  HB3  C LYS A 1 59  ? -7.90800  -11.25400 32.92800 0.158 15.59069 ? 82  LYS A HB3  1 
ATOM   908  H  HG2  B LYS A 1 59  ? -6.54300  -12.60800 34.16900 0.842 19.46630 ? 82  LYS A HG2  1 
ATOM   909  H  HG2  C LYS A 1 59  ? -6.56500  -12.70000 34.13100 0.158 16.56879 ? 82  LYS A HG2  1 
ATOM   910  H  HG3  B LYS A 1 59  ? -7.68500  -12.00300 35.09400 0.842 19.46630 ? 82  LYS A HG3  1 
ATOM   911  H  HG3  C LYS A 1 59  ? -7.70200  -12.14200 35.09100 0.158 16.56879 ? 82  LYS A HG3  1 
ATOM   912  H  HD2  B LYS A 1 59  ? -8.82600  -14.01500 35.03400 0.842 24.45318 ? 82  LYS A HD2  1 
ATOM   913  H  HD2  C LYS A 1 59  ? -8.89700  -14.13000 34.83400 0.158 18.18193 ? 82  LYS A HD2  1 
ATOM   914  H  HD3  B LYS A 1 59  ? -7.73100  -14.62300 34.05500 0.842 24.45318 ? 82  LYS A HD3  1 
ATOM   915  H  HD3  C LYS A 1 59  ? -7.76500  -14.68700 33.86800 0.158 18.18193 ? 82  LYS A HD3  1 
ATOM   916  H  HE2  B LYS A 1 59  ? -6.13300  -14.46700 35.75100 0.842 29.24653 ? 82  LYS A HE2  1 
ATOM   917  H  HE2  C LYS A 1 59  ? -7.40400  -14.14000 36.61200 0.158 19.56133 ? 82  LYS A HE2  1 
ATOM   918  H  HE3  B LYS A 1 59  ? -7.23200  -13.86700 36.72900 0.842 29.24653 ? 82  LYS A HE3  1 
ATOM   919  H  HE3  C LYS A 1 59  ? -7.46900  -15.59500 35.97700 0.158 19.56133 ? 82  LYS A HE3  1 
ATOM   920  H  HZ1  B LYS A 1 59  ? -7.29900  -16.41500 35.75100 0.842 31.58747 ? 82  LYS A HZ1  1 
ATOM   921  H  HZ1  C LYS A 1 59  ? -5.51800  -15.07200 34.86800 0.158 20.29990 ? 82  LYS A HZ1  1 
ATOM   922  H  HZ2  B LYS A 1 59  ? -6.94500  -16.08100 37.11500 0.842 31.58747 ? 82  LYS A HZ2  1 
ATOM   923  H  HZ2  C LYS A 1 59  ? -5.44100  -13.80900 35.57400 0.158 20.29990 ? 82  LYS A HZ2  1 
ATOM   924  H  HZ3  B LYS A 1 59  ? -8.29900  -15.86800 36.64600 0.842 31.58747 ? 82  LYS A HZ3  1 
ATOM   925  H  HZ3  C LYS A 1 59  ? -5.31800  -15.05500 36.30300 0.158 20.29990 ? 82  LYS A HZ3  1 
ATOM   926  N  N    . LYS A 1 60  ? -9.99800  -9.82200  34.32400 1.000 12.63667 ? 83  LYS A N    1 
ATOM   927  C  CA   . LYS A 1 60  ? -10.32300 -8.89200  35.40500 1.000 14.23027 ? 83  LYS A CA   1 
ATOM   928  C  C    . LYS A 1 60  ? -11.76500 -9.08200  35.86300 1.000 14.06138 ? 83  LYS A C    1 
ATOM   929  O  O    . LYS A 1 60  ? -12.06200 -8.98400  37.06100 1.000 15.75756 ? 83  LYS A O    1 
ATOM   930  C  CB   . LYS A 1 60  ? -10.06500 -7.46100  34.91500 1.000 14.69320 ? 83  LYS A CB   1 
ATOM   931  C  CG   . LYS A 1 60  ? -10.13800 -6.34000  35.97500 1.000 16.34264 ? 83  LYS A CG   1 
ATOM   932  C  CD   . LYS A 1 60  ? -9.65100  -5.00200  35.37300 1.000 17.97817 ? 83  LYS A CD   1 
ATOM   933  C  CE   . LYS A 1 60  ? -9.59600  -3.85600  36.37900 1.000 21.82270 ? 83  LYS A CE   1 
ATOM   934  N  NZ   . LYS A 1 60  ? -10.93000 -3.36600  36.76900 1.000 22.81803 ? 83  LYS A NZ   1 
ATOM   935  H  H    . LYS A 1 60  ? -9.74700  -9.44500  33.59200 1.000 15.16206 ? 83  LYS A H    1 
ATOM   936  H  HA   . LYS A 1 60  ? -9.75600  -9.05200  36.17500 1.000 17.07437 ? 83  LYS A HA   1 
ATOM   937  H  HB2  . LYS A 1 60  ? -9.17400  -7.43100  34.53200 1.000 17.62989 ? 83  LYS A HB2  1 
ATOM   938  H  HB3  . LYS A 1 60  ? -10.72600 -7.25200  34.23600 1.000 17.62989 ? 83  LYS A HB3  1 
ATOM   939  H  HG2  . LYS A 1 60  ? -11.05500 -6.23100  36.27200 1.000 19.60922 ? 83  LYS A HG2  1 
ATOM   940  H  HG3  . LYS A 1 60  ? -9.57100  -6.56600  36.72900 1.000 19.60922 ? 83  LYS A HG3  1 
ATOM   941  H  HD2  . LYS A 1 60  ? -8.75700  -5.12600  35.01800 1.000 21.57185 ? 83  LYS A HD2  1 
ATOM   942  H  HD3  . LYS A 1 60  ? -10.25700 -4.74000  34.66200 1.000 21.57185 ? 83  LYS A HD3  1 
ATOM   943  H  HE2  . LYS A 1 60  ? -9.14500  -4.16300  37.18100 1.000 26.18529 ? 83  LYS A HE2  1 
ATOM   944  H  HE3  . LYS A 1 60  ? -9.10900  -3.11500  35.98700 1.000 26.18529 ? 83  LYS A HE3  1 
ATOM   945  H  HZ1  . LYS A 1 60  ? -10.90200 -2.48800  36.91100 1.000 27.37969 ? 83  LYS A HZ1  1 
ATOM   946  H  HZ2  . LYS A 1 60  ? -11.51700 -3.53600  36.12300 1.000 27.37969 ? 83  LYS A HZ2  1 
ATOM   947  H  HZ3  . LYS A 1 60  ? -11.19600 -3.77100  37.51600 1.000 27.37969 ? 83  LYS A HZ3  1 
ATOM   948  N  N    . SER A 1 61  ? -12.67500 -9.38100  34.92600 1.000 13.59235 ? 84  SER A N    1 
ATOM   949  C  CA   . SER A 1 61  ? -14.09200 -9.52400  35.24900 1.000 14.35856 ? 84  SER A CA   1 
ATOM   950  C  C    . SER A 1 61  ? -14.39000 -10.76200 36.08200 1.000 15.74311 ? 84  SER A C    1 
ATOM   951  O  O    . SER A 1 61  ? -15.46800 -10.84400 36.68100 1.000 17.11849 ? 84  SER A O    1 
ATOM   952  C  CB   . SER A 1 61  ? -14.94600 -9.54500  33.97500 1.000 13.89288 ? 84  SER A CB   1 
ATOM   953  O  OG   . SER A 1 61  ? -14.94200 -10.81100 33.32800 1.000 14.83801 ? 84  SER A OG   1 
ATOM   954  H  H    . SER A 1 61  ? -12.49300 -9.50600  34.09500 1.000 16.30887 ? 84  SER A H    1 
ATOM   955  H  HA   . SER A 1 61  ? -14.35100 -8.74600  35.76700 1.000 17.22832 ? 84  SER A HA   1 
ATOM   956  H  HB2  . SER A 1 61  ? -15.86000 -9.32500  34.21300 1.000 16.66950 ? 84  SER A HB2  1 
ATOM   957  H  HB3  . SER A 1 61  ? -14.59500 -8.88400  33.35800 1.000 16.66950 ? 84  SER A HB3  1 
ATOM   958  H  HG   . SER A 1 61  ? -14.15200 -11.07500 33.21800 1.000 17.80366 ? 84  SER A HG   1 
ATOM   959  N  N    . GLU A 1 62  ? -13.46500 -11.71900 36.14700 1.000 16.21393 ? 85  GLU A N    1 
ATOM   960  C  CA   . GLU A 1 62  ? -13.69800 -12.90800 36.95500 1.000 17.04131 ? 85  GLU A CA   1 
ATOM   961  C  C    . GLU A 1 62  ? -13.80800 -12.56000 38.43200 1.000 18.95872 ? 85  GLU A C    1 
ATOM   962  O  O    . GLU A 1 62  ? -14.48700 -13.26300 39.18700 1.000 21.58382 ? 85  GLU A O    1 
ATOM   963  C  CB   . GLU A 1 62  ? -12.57500 -13.91700 36.73500 1.000 17.95801 ? 85  GLU A CB   1 
ATOM   964  C  CG   . GLU A 1 62  ? -12.58800 -14.49000 35.33900 1.000 19.17000 ? 85  GLU A CG   1 
ATOM   965  C  CD   . GLU A 1 62  ? -11.43300 -15.41200 35.06000 1.000 21.71738 ? 85  GLU A CD   1 
ATOM   966  O  OE1  . GLU A 1 62  ? -10.75500 -15.85500 36.00900 1.000 23.92697 ? 85  GLU A OE1  1 
ATOM   967  O  OE2  . GLU A 1 62  ? -11.21600 -15.68800 33.87600 1.000 21.98959 ? 85  GLU A OE2  1 
ATOM   968  H  H    . GLU A 1 62  ? -12.70800 -11.70300 35.73900 1.000 19.45477 ? 85  GLU A H    1 
ATOM   969  H  HA   . GLU A 1 62  ? -14.53100 -13.31900 36.67700 1.000 20.44763 ? 85  GLU A HA   1 
ATOM   970  H  HB2  . GLU A 1 62  ? -11.72200 -13.47800 36.87400 1.000 21.54766 ? 85  GLU A HB2  1 
ATOM   971  H  HB3  . GLU A 1 62  ? -12.67800 -14.64900 37.36300 1.000 21.54766 ? 85  GLU A HB3  1 
ATOM   972  H  HG2  . GLU A 1 62  ? -13.40700 -14.99400 35.21500 1.000 23.00206 ? 85  GLU A HG2  1 
ATOM   973  H  HG3  . GLU A 1 62  ? -12.54700 -13.76000 34.70100 1.000 23.00206 ? 85  GLU A HG3  1 
ATOM   974  N  N    A SER A 1 63  ? -13.15300 -11.48800 38.86500 0.656 19.55918 ? 86  SER A N    1 
ATOM   975  N  N    B SER A 1 63  ? -13.14000 -11.49000 38.85800 0.344 19.46760 ? 86  SER A N    1 
ATOM   976  C  CA   A SER A 1 63  ? -13.20400 -11.05900 40.25400 0.656 21.87339 ? 86  SER A CA   1 
ATOM   977  C  CA   B SER A 1 63  ? -13.17000 -11.04200 40.24000 0.344 20.80068 ? 86  SER A CA   1 
ATOM   978  C  C    A SER A 1 63  ? -13.97800 -9.76300  40.43900 0.656 22.35147 ? 86  SER A C    1 
ATOM   979  C  C    B SER A 1 63  ? -14.02400 -9.80100  40.44200 0.344 21.64028 ? 86  SER A C    1 
ATOM   980  O  O    A SER A 1 63  ? -14.06500 -9.26500  41.56600 0.656 24.59100 ? 86  SER A O    1 
ATOM   981  O  O    B SER A 1 63  ? -14.22300 -9.38700  41.58900 0.344 22.94694 ? 86  SER A O    1 
ATOM   982  C  CB   A SER A 1 63  ? -11.78500 -10.91000 40.81000 0.656 23.54145 ? 86  SER A CB   1 
ATOM   983  C  CB   B SER A 1 63  ? -11.74300 -10.74400 40.72200 0.344 21.24212 ? 86  SER A CB   1 
ATOM   984  O  OG   A SER A 1 63  ? -10.99800 -10.08300 39.97500 0.656 25.06467 ? 86  SER A OG   1 
ATOM   985  O  OG   B SER A 1 63  ? -10.91400 -11.88300 40.57800 0.344 21.48210 ? 86  SER A OG   1 
ATOM   986  H  H    A SER A 1 63  ? -12.66600 -10.98700 38.36400 0.656 23.46907 ? 86  SER A H    1 
ATOM   987  H  H    B SER A 1 63  ? -12.65200 -10.99700 38.35000 0.344 23.35917 ? 86  SER A H    1 
ATOM   988  H  HA   A SER A 1 63  ? -13.65100 -11.74300 40.77800 0.656 26.24612 ? 86  SER A HA   1 
ATOM   989  H  HA   B SER A 1 63  ? -13.53300 -11.75000 40.79400 0.344 24.95886 ? 86  SER A HA   1 
ATOM   990  H  HB2  A SER A 1 63  ? -11.83300 -10.51100 41.69300 0.656 28.24779 ? 86  SER A HB2  1 
ATOM   991  H  HB2  B SER A 1 63  ? -11.37600 -10.01800 40.19300 0.344 25.48860 ? 86  SER A HB2  1 
ATOM   992  H  HB3  A SER A 1 63  ? -11.37300 -11.78600 40.86300 0.656 28.24779 ? 86  SER A HB3  1 
ATOM   993  H  HB3  B SER A 1 63  ? -11.77200 -10.49200 41.65800 0.344 25.48860 ? 86  SER A HB3  1 
ATOM   994  H  HG   A SER A 1 63  ? -11.29100 -9.29600  39.99200 0.656 30.07566 ? 86  SER A HG   1 
ATOM   995  H  HG   B SER A 1 63  ? -10.88600 -12.11700 39.77100 0.344 25.77656 ? 86  SER A HG   1 
ATOM   996  N  N    . GLU A 1 64  ? -14.54900 -9.21900  39.36600 1.000 21.77409 ? 87  GLU A N    1 
ATOM   997  C  CA   . GLU A 1 64  ? -15.33900 -7.99200  39.41300 1.000 22.72486 ? 87  GLU A CA   1 
ATOM   998  C  C    . GLU A 1 64  ? -16.56900 -8.24600  38.55300 1.000 24.24598 ? 87  GLU A C    1 
ATOM   999  O  O    . GLU A 1 64  ? -16.57400 -7.95000  37.34800 1.000 22.69872 ? 87  GLU A O    1 
ATOM   1000 C  CB   . GLU A 1 64  ? -14.55600 -6.80500  38.86300 1.000 24.48861 ? 87  GLU A CB   1 
ATOM   1001 C  CG   . GLU A 1 64  ? -13.24700 -6.54700  39.56100 1.000 27.21317 ? 87  GLU A CG   1 
ATOM   1002 C  CD   . GLU A 1 64  ? -12.47600 -5.40400  38.92600 1.000 29.93431 ? 87  GLU A CD   1 
ATOM   1003 O  OE1  . GLU A 1 64  ? -13.11600 -4.53900  38.29500 1.000 31.98314 ? 87  GLU A OE1  1 
ATOM   1004 O  OE2  . GLU A 1 64  ? -11.23600 -5.37500  39.05200 1.000 30.41013 ? 87  GLU A OE2  1 
ATOM   1005 H  H    . GLU A 1 64  ? -14.49300 -9.54900  38.57400 1.000 26.12696 ? 87  GLU A H    1 
ATOM   1006 H  HA   . GLU A 1 64  ? -15.59400 -7.79000  40.32700 1.000 27.26788 ? 87  GLU A HA   1 
ATOM   1007 H  HB2  . GLU A 1 64  ? -14.36200 -6.96800  37.92700 1.000 29.38438 ? 87  GLU A HB2  1 
ATOM   1008 H  HB3  . GLU A 1 64  ? -15.09900 -6.00600  38.95500 1.000 29.38438 ? 87  GLU A HB3  1 
ATOM   1009 H  HG2  . GLU A 1 64  ? -13.41900 -6.31800  40.48700 1.000 32.65386 ? 87  GLU A HG2  1 
ATOM   1010 H  HG3  . GLU A 1 64  ? -12.69800 -7.34500  39.51300 1.000 32.65386 ? 87  GLU A HG3  1 
ATOM   1011 N  N    A PRO A 1 65  ? -17.62000 -8.81900  39.13100 0.357 26.43945 ? 88  PRO A N    1 
ATOM   1012 N  N    B PRO A 1 65  ? -17.65300 -8.75600  39.14400 0.643 27.32454 ? 88  PRO A N    1 
ATOM   1013 C  CA   A PRO A 1 65  ? -18.87900 -8.92300  38.39800 0.357 27.74247 ? 88  PRO A CA   1 
ATOM   1014 C  CA   B PRO A 1 65  ? -18.77700 -9.24500  38.32400 0.643 29.50349 ? 88  PRO A CA   1 
ATOM   1015 C  C    A PRO A 1 65  ? -19.41900 -7.53000  38.15500 0.357 27.22000 ? 88  PRO A C    1 
ATOM   1016 C  C    B PRO A 1 65  ? -19.49900 -8.17400  37.52300 0.643 29.47272 ? 88  PRO A C    1 
ATOM   1017 O  O    A PRO A 1 65  ? -19.21200 -6.60800  38.94600 0.357 27.62296 ? 88  PRO A O    1 
ATOM   1018 O  O    B PRO A 1 65  ? -20.10900 -8.50800  36.49900 0.643 31.13150 ? 88  PRO A O    1 
ATOM   1019 C  CB   A PRO A 1 65  ? -19.78100 -9.71800  39.34500 0.357 28.47637 ? 88  PRO A CB   1 
ATOM   1020 C  CB   B PRO A 1 65  ? -19.71100 -9.88200  39.36300 0.643 30.41969 ? 88  PRO A CB   1 
ATOM   1021 C  CG   A PRO A 1 65  ? -19.27700 -9.38700  40.69400 0.357 28.26661 ? 88  PRO A CG   1 
ATOM   1022 C  CG   B PRO A 1 65  ? -19.41900 -9.13500  40.62100 0.643 30.26902 ? 88  PRO A CG   1 
ATOM   1023 C  CD   A PRO A 1 65  ? -17.79100 -9.14300  40.56000 0.357 27.51211 ? 88  PRO A CD   1 
ATOM   1024 C  CD   B PRO A 1 65  ? -17.94800 -8.82800  40.58500 0.643 29.18846 ? 88  PRO A CD   1 
ATOM   1025 H  HA   A PRO A 1 65  ? -18.79000 -9.41600  37.56700 0.357 33.28902 ? 88  PRO A HA   1 
ATOM   1026 H  HA   B PRO A 1 65  ? -18.44600 -9.91700  37.70800 0.643 35.40224 ? 88  PRO A HA   1 
ATOM   1027 H  HB2  A PRO A 1 65  ? -20.70300 -9.43800  39.23800 0.357 34.16970 ? 88  PRO A HB2  1 
ATOM   1028 H  HB2  B PRO A 1 65  ? -20.63600 -9.76800  39.09400 0.643 36.50167 ? 88  PRO A HB2  1 
ATOM   1029 H  HB3  A PRO A 1 65  ? -19.69800 -10.66700 39.16500 0.357 34.16970 ? 88  PRO A HB3  1 
ATOM   1030 H  HB3  B PRO A 1 65  ? -19.50700 -10.82600 39.46000 0.643 36.50167 ? 88  PRO A HB3  1 
ATOM   1031 H  HG2  A PRO A 1 65  ? -19.72400 -8.58900  41.01900 0.357 33.91799 ? 88  PRO A HG2  1 
ATOM   1032 H  HG2  B PRO A 1 65  ? -19.94000 -8.31700  40.64400 0.643 36.32087 ? 88  PRO A HG2  1 
ATOM   1033 H  HG3  A PRO A 1 65  ? -19.44600 -10.13000 41.29400 0.357 33.91799 ? 88  PRO A HG3  1 
ATOM   1034 H  HG3  B PRO A 1 65  ? -19.63500 -9.68900  41.38700 0.643 36.32087 ? 88  PRO A HG3  1 
ATOM   1035 H  HD2  A PRO A 1 65  ? -17.51300 -8.40000  41.11700 0.357 33.01258 ? 88  PRO A HD2  1 
ATOM   1036 H  HD2  B PRO A 1 65  ? -17.76100 -7.98100  41.01900 0.643 35.02420 ? 88  PRO A HD2  1 
ATOM   1037 H  HD3  A PRO A 1 65  ? -17.29000 -9.94000  40.79400 0.357 33.01258 ? 88  PRO A HD3  1 
ATOM   1038 H  HD3  B PRO A 1 65  ? -17.43700 -9.53700  41.00700 0.643 35.02420 ? 88  PRO A HD3  1 
ATOM   1039 N  N    A ASN A 1 66  ? -20.10300 -7.38100  37.03300 0.357 26.18162 ? 89  ASN A N    1 
ATOM   1040 N  N    B ASN A 1 66  ? -19.48800 -6.91500  37.96600 0.643 27.71278 ? 89  ASN A N    1 
ATOM   1041 C  CA   A ASN A 1 66  ? -20.50700 -6.08900  36.50500 0.357 25.61177 ? 89  ASN A CA   1 
ATOM   1042 C  CA   B ASN A 1 66  ? -20.17100 -5.84600  37.24800 0.643 26.94726 ? 89  ASN A CA   1 
ATOM   1043 C  C    A ASN A 1 66  ? -19.33500 -5.22900  36.04700 0.357 23.84937 ? 89  ASN A C    1 
ATOM   1044 C  C    B ASN A 1 66  ? -19.33200 -5.26800  36.12200 0.643 24.00839 ? 89  ASN A C    1 
ATOM   1045 O  O    A ASN A 1 66  ? -19.53400 -4.03800  35.77400 0.357 24.61623 ? 89  ASN A O    1 
ATOM   1046 O  O    B ASN A 1 66  ? -19.80300 -4.37500  35.41100 0.643 24.34786 ? 89  ASN A O    1 
ATOM   1047 C  CB   A ASN A 1 66  ? -21.41300 -5.30100  37.45900 0.357 25.95324 ? 89  ASN A CB   1 
ATOM   1048 C  CB   B ASN A 1 66  ? -20.54000 -4.70900  38.20500 0.643 29.26740 ? 89  ASN A CB   1 
ATOM   1049 C  CG   A ASN A 1 66  ? -22.75200 -4.98800  36.83500 0.357 25.99854 ? 89  ASN A CG   1 
ATOM   1050 C  CG   B ASN A 1 66  ? -21.58100 -5.11700  39.21200 0.643 31.60843 ? 89  ASN A CG   1 
ATOM   1051 O  OD1  A ASN A 1 66  ? -23.25400 -5.76500  36.02900 0.357 26.62508 ? 89  ASN A OD1  1 
ATOM   1052 O  OD1  B ASN A 1 66  ? -22.74500 -5.30800  38.86900 0.643 32.63200 ? 89  ASN A OD1  1 
ATOM   1053 N  ND2  A ASN A 1 66  ? -23.31800 -3.84100  37.16900 0.357 25.78796 ? 89  ASN A ND2  1 
ATOM   1054 N  ND2  B ASN A 1 66  ? -21.17100 -5.25400  40.46600 0.643 32.37185 ? 89  ASN A ND2  1 
ATOM   1055 H  H    A ASN A 1 66  ? -20.35300 -8.04000  36.54200 0.357 31.41599 ? 89  ASN A H    1 
ATOM   1056 H  H    B ASN A 1 66  ? -19.08800 -6.65700  38.68200 0.643 33.25338 ? 89  ASN A H    1 
ATOM   1057 H  HA   A ASN A 1 66  ? -21.04100 -6.26700  35.71600 0.357 30.73217 ? 89  ASN A HA   1 
ATOM   1058 H  HA   B ASN A 1 66  ? -20.99000 -6.21100  36.87700 0.643 32.33477 ? 89  ASN A HA   1 
ATOM   1059 H  HB2  A ASN A 1 66  ? -21.56700 -5.82600  38.26000 0.357 31.14194 ? 89  ASN A HB2  1 
ATOM   1060 H  HB2  B ASN A 1 66  ? -19.74600 -4.43200  38.68800 0.643 35.11893 ? 89  ASN A HB2  1 
ATOM   1061 H  HB3  A ASN A 1 66  ? -20.98200 -4.46300  37.69000 0.357 31.14194 ? 89  ASN A HB3  1 
ATOM   1062 H  HB3  B ASN A 1 66  ? -20.89200 -3.96500  37.69200 0.643 35.11893 ? 89  ASN A HB3  1 
ATOM   1063 H  HD21 A ASN A 1 66  ? -24.08100 -3.62500  36.83500 0.357 30.94361 ? 89  ASN A HD21 1 
ATOM   1064 H  HD21 B ASN A 1 66  ? -20.34800 -5.11100  40.66700 0.643 38.84428 ? 89  ASN A HD21 1 
ATOM   1065 H  HD22 A ASN A 1 66  ? -22.92400 -3.31000  37.71900 0.357 30.94361 ? 89  ASN A HD22 1 
ATOM   1066 H  HD22 B ASN A 1 66  ? -21.72900 -5.48600  41.07800 0.643 38.84428 ? 89  ASN A HD22 1 
ATOM   1067 N  N    . LEU A 1 67  ? -18.11800 -5.78000  35.93200 1.000 22.01078 ? 90  LEU A N    1 
ATOM   1068 C  CA   . LEU A 1 67  ? -17.11900 -5.07500  35.14200 1.000 17.66746 ? 90  LEU A CA   1 
ATOM   1069 C  C    . LEU A 1 67  ? -17.58000 -4.90200  33.69900 1.000 16.19068 ? 90  LEU A C    1 
ATOM   1070 O  O    . LEU A 1 67  ? -17.46800 -3.81500  33.13100 1.000 15.90785 ? 90  LEU A O    1 
ATOM   1071 C  CB   . LEU A 1 67  ? -15.77400 -5.79400  35.20300 1.000 17.48768 ? 90  LEU A CB   1 
ATOM   1072 C  CG   . LEU A 1 67  ? -14.65600 -5.02700  34.49700 1.000 17.40849 ? 90  LEU A CG   1 
ATOM   1073 C  CD1  . LEU A 1 67  ? -14.35200 -3.69600  35.20400 1.000 19.51462 ? 90  LEU A CD1  1 
ATOM   1074 C  CD2  . LEU A 1 67  ? -13.40900 -5.88400  34.44200 1.000 18.42620 ? 90  LEU A CD2  1 
ATOM   1075 H  H    . LEU A 1 67  ? -17.85300 -6.53300  36.25000 1.000 26.41099 ? 90  LEU A H    1 
ATOM   1076 H  HA   . LEU A 1 67  ? -16.99400 -4.19300  35.52700 1.000 21.19901 ? 90  LEU A HA   1 
ATOM   1077 H  HB2  . LEU A 1 67  ? -15.52000 -5.90800  36.13200 1.000 20.98327 ? 90  LEU A HB2  1 
ATOM   1078 H  HB3  . LEU A 1 67  ? -15.86100 -6.66000  34.77400 1.000 20.98327 ? 90  LEU A HB3  1 
ATOM   1079 H  HG   . LEU A 1 67  ? -14.94200 -4.81700  33.59500 1.000 20.88824 ? 90  LEU A HG   1 
ATOM   1080 H  HD11 . LEU A 1 67  ? -14.35900 -2.98200  34.54800 1.000 23.41559 ? 90  LEU A HD11 1 
ATOM   1081 H  HD12 . LEU A 1 67  ? -15.03200 -3.53400  35.87700 1.000 23.41559 ? 90  LEU A HD12 1 
ATOM   1082 H  HD13 . LEU A 1 67  ? -13.47900 -3.75300  35.62200 1.000 23.41559 ? 90  LEU A HD13 1 
ATOM   1083 H  HD21 . LEU A 1 67  ? -12.69000 -5.37000  34.04100 1.000 22.10949 ? 90  LEU A HD21 1 
ATOM   1084 H  HD22 . LEU A 1 67  ? -13.16500 -6.14500  35.34400 1.000 22.10949 ? 90  LEU A HD22 1 
ATOM   1085 H  HD23 . LEU A 1 67  ? -13.59000 -6.67200  33.90700 1.000 22.10949 ? 90  LEU A HD23 1 
ATOM   1086 N  N    . LEU A 1 68  ? -18.09200 -5.96500  33.08000 1.000 15.25659 ? 91  LEU A N    1 
ATOM   1087 C  CA   . LEU A 1 68  ? -18.45400 -5.84500  31.67200 1.000 14.60562 ? 91  LEU A CA   1 
ATOM   1088 C  C    . LEU A 1 68  ? -19.58300 -4.84900  31.45000 1.000 13.88067 ? 91  LEU A C    1 
ATOM   1089 O  O    . LEU A 1 68  ? -19.70800 -4.30800  30.35300 1.000 14.33456 ? 91  LEU A O    1 
ATOM   1090 C  CB   . LEU A 1 68  ? -18.80100 -7.21300  31.08600 1.000 16.16675 ? 91  LEU A CB   1 
ATOM   1091 C  CG   . LEU A 1 68  ? -17.64500 -8.21400  31.02400 1.000 18.63746 ? 91  LEU A CG   1 
ATOM   1092 C  CD1  . LEU A 1 68  ? -18.07600 -9.51700  30.35400 1.000 19.88227 ? 91  LEU A CD1  1 
ATOM   1093 C  CD2  . LEU A 1 68  ? -16.44800 -7.64000  30.29100 1.000 20.19926 ? 91  LEU A CD2  1 
ATOM   1094 H  H    . LEU A 1 68  ? -18.23400 -6.73400  33.43800 1.000 18.30596 ? 91  LEU A H    1 
ATOM   1095 H  HA   . LEU A 1 68  ? -17.68500 -5.51900  31.17900 1.000 17.52480 ? 91  LEU A HA   1 
ATOM   1096 H  HB2  . LEU A 1 68  ? -19.49900 -7.61000  31.63200 1.000 19.39816 ? 91  LEU A HB2  1 
ATOM   1097 H  HB3  . LEU A 1 68  ? -19.12200 -7.08400  30.18000 1.000 19.39816 ? 91  LEU A HB3  1 
ATOM   1098 H  HG   . LEU A 1 68  ? -17.37900 -8.40600  31.93700 1.000 22.36301 ? 91  LEU A HG   1 
ATOM   1099 H  HD11 . LEU A 1 68  ? -17.36000 -10.16600 30.43600 1.000 23.85678 ? 91  LEU A HD11 1 
ATOM   1100 H  HD12 . LEU A 1 68  ? -18.87500 -9.84800  30.79300 1.000 23.85678 ? 91  LEU A HD12 1 
ATOM   1101 H  HD13 . LEU A 1 68  ? -18.26000 -9.34400  29.41800 1.000 23.85678 ? 91  LEU A HD13 1 
ATOM   1102 H  HD21 . LEU A 1 68  ? -15.80500 -8.34900  30.13200 1.000 24.23717 ? 91  LEU A HD21 1 
ATOM   1103 H  HD22 . LEU A 1 68  ? -16.74400 -7.26700  29.44600 1.000 24.23717 ? 91  LEU A HD22 1 
ATOM   1104 H  HD23 . LEU A 1 68  ? -16.04600 -6.94600  30.83700 1.000 24.23717 ? 91  LEU A HD23 1 
ATOM   1105 N  N    . ASN A 1 69  ? -20.39400 -4.57700  32.46900 1.000 14.29067 ? 92  ASN A N    1 
ATOM   1106 C  CA   . ASN A 1 69  ? -21.45700 -3.59100  32.36400 1.000 15.66814 ? 92  ASN A CA   1 
ATOM   1107 C  C    . ASN A 1 69  ? -20.99900 -2.16800  32.64900 1.000 15.11129 ? 92  ASN A C    1 
ATOM   1108 O  O    . ASN A 1 69  ? -21.78900 -1.23900  32.44800 1.000 15.85385 ? 92  ASN A O    1 
ATOM   1109 C  CB   . ASN A 1 69  ? -22.59900 -3.92900  33.31800 1.000 17.08942 ? 92  ASN A CB   1 
ATOM   1110 C  CG   . ASN A 1 69  ? -23.39100 -5.13200  32.86800 1.000 20.48499 ? 92  ASN A CG   1 
ATOM   1111 O  OD1  . ASN A 1 69  ? -23.55000 -5.37100  31.66800 1.000 22.74872 ? 92  ASN A OD1  1 
ATOM   1112 N  ND2  . ASN A 1 69  ? -23.90200 -5.89400  33.82600 1.000 24.37706 ? 92  ASN A ND2  1 
ATOM   1113 H  H    . ASN A 1 69  ? -20.34500 -4.95700  33.23900 1.000 17.14685 ? 92  ASN A H    1 
ATOM   1114 H  HA   . ASN A 1 69  ? -21.79700 -3.62300  31.45600 1.000 18.79982 ? 92  ASN A HA   1 
ATOM   1115 H  HB2  . ASN A 1 69  ? -22.23300 -4.12000  34.19600 1.000 20.50536 ? 92  ASN A HB2  1 
ATOM   1116 H  HB3  . ASN A 1 69  ? -23.20400 -3.17200  33.37000 1.000 20.50536 ? 92  ASN A HB3  1 
ATOM   1117 H  HD21 . ASN A 1 69  ? -24.36200 -6.59100  33.62100 1.000 29.25052 ? 92  ASN A HD21 1 
ATOM   1118 H  HD22 . ASN A 1 69  ? -23.77400 -5.69000  34.65200 1.000 29.25052 ? 92  ASN A HD22 1 
ATOM   1119 N  N    . GLN A 1 70  ? -19.76000 -1.97400  33.10200 1.000 15.01898 ? 93  GLN A N    1 
ATOM   1120 C  CA   . GLN A 1 70  ? -19.28200 -0.63700  33.42200 1.000 15.59102 ? 93  GLN A CA   1 
ATOM   1121 C  C    . GLN A 1 70  ? -19.29800 0.25000   32.18400 1.000 15.17149 ? 93  GLN A C    1 
ATOM   1122 O  O    . GLN A 1 70  ? -18.90100 -0.16600  31.09200 1.000 15.72575 ? 93  GLN A O    1 
ATOM   1123 C  CB   . GLN A 1 70  ? -17.86300 -0.71300  33.99500 1.000 18.49892 ? 93  GLN A CB   1 
ATOM   1124 C  CG   . GLN A 1 70  ? -17.30500 0.63000   34.43600 1.000 21.92120 ? 93  GLN A CG   1 
ATOM   1125 C  CD   . GLN A 1 70  ? -15.91900 0.52800   35.05100 1.000 25.06061 ? 93  GLN A CD   1 
ATOM   1126 O  OE1  . GLN A 1 70  ? -15.62100 -0.40700  35.79800 1.000 27.20253 ? 93  GLN A OE1  1 
ATOM   1127 N  NE2  . GLN A 1 70  ? -15.07300 1.50700   34.76200 1.000 26.12808 ? 93  GLN A NE2  1 
ATOM   1128 H  H    . GLN A 1 70  ? -19.18200 -2.59700  33.23000 1.000 18.02083 ? 93  GLN A H    1 
ATOM   1129 H  HA   . GLN A 1 70  ? -19.86200 -0.23800  34.08900 1.000 18.70728 ? 93  GLN A HA   1 
ATOM   1130 H  HB2  . GLN A 1 70  ? -17.87000 -1.29800  34.76800 1.000 22.19676 ? 93  GLN A HB2  1 
ATOM   1131 H  HB3  . GLN A 1 70  ? -17.27100 -1.06900  33.31400 1.000 22.19676 ? 93  GLN A HB3  1 
ATOM   1132 H  HG2  . GLN A 1 70  ? -17.24700 1.21500   33.66500 1.000 26.30349 ? 93  GLN A HG2  1 
ATOM   1133 H  HG3  . GLN A 1 70  ? -17.89800 1.01400   35.10000 1.000 26.30349 ? 93  GLN A HG3  1 
ATOM   1134 H  HE21 . GLN A 1 70  ? -15.32100 2.15300   34.25200 1.000 31.35175 ? 93  GLN A HE21 1 
ATOM   1135 H  HE22 . GLN A 1 70  ? -14.27600 1.49600   35.08500 1.000 31.35175 ? 93  GLN A HE22 1 
ATOM   1136 N  N    . ARG A 1 71  ? -19.75200 1.48900   32.36700 1.000 16.00449 ? 94  ARG A N    1 
ATOM   1137 C  CA   . ARG A 1 71  ? -19.91500 2.43900   31.27500 1.000 16.45508 ? 94  ARG A CA   1 
ATOM   1138 C  C    . ARG A 1 71  ? -18.64200 3.26300   31.10200 1.000 15.86508 ? 94  ARG A C    1 
ATOM   1139 O  O    . ARG A 1 71  ? -18.01500 3.68200   32.08000 1.000 18.04236 ? 94  ARG A O    1 
ATOM   1140 C  CB   . ARG A 1 71  ? -21.07200 3.40700   31.56100 1.000 17.91369 ? 94  ARG A CB   1 
ATOM   1141 C  CG   . ARG A 1 71  ? -22.41200 2.78700   31.99400 1.000 18.72455 ? 94  ARG A CG   1 
ATOM   1142 C  CD   . ARG A 1 71  ? -22.99900 1.82700   30.96400 1.000 18.01302 ? 94  ARG A CD   1 
ATOM   1143 N  NE   . ARG A 1 71  ? -23.26400 2.42500   29.66100 1.000 17.44647 ? 94  ARG A NE   1 
ATOM   1144 C  CZ   . ARG A 1 71  ? -23.77900 1.76900   28.62700 1.000 17.25056 ? 94  ARG A CZ   1 
ATOM   1145 N  NH1  . ARG A 1 71  ? -24.17000 0.50500   28.72700 1.000 17.65899 ? 94  ARG A NH1  1 
ATOM   1146 N  NH2  . ARG A 1 71  ? -23.91500 2.39500   27.46300 1.000 17.94755 ? 94  ARG A NH2  1 
ATOM   1147 H  H    . ARG A 1 71  ? -19.97700 1.80800   33.13400 1.000 19.20344 ? 94  ARG A H    1 
ATOM   1148 H  HA   . ARG A 1 71  ? -20.10200 1.94600   30.46100 1.000 19.74415 ? 94  ARG A HA   1 
ATOM   1149 H  HB2  . ARG A 1 71  ? -20.79400 4.00200   32.27500 1.000 21.49447 ? 94  ARG A HB2  1 
ATOM   1150 H  HB3  . ARG A 1 71  ? -21.24400 3.91400   30.75300 1.000 21.49447 ? 94  ARG A HB3  1 
ATOM   1151 H  HG2  . ARG A 1 71  ? -22.27800 2.29200   32.81700 1.000 22.46751 ? 94  ARG A HG2  1 
ATOM   1152 H  HG3  . ARG A 1 71  ? -23.05600 3.49800   32.13600 1.000 22.46751 ? 94  ARG A HG3  1 
ATOM   1153 H  HD2  . ARG A 1 71  ? -22.37400 1.09800   30.82900 1.000 21.61368 ? 94  ARG A HD2  1 
ATOM   1154 H  HD3  . ARG A 1 71  ? -23.84000 1.48500   31.30500 1.000 21.61368 ? 94  ARG A HD3  1 
ATOM   1155 H  HE   . ARG A 1 71  ? -23.07400 3.25700   29.55500 1.000 20.93382 ? 94  ARG A HE   1 
ATOM   1156 H  HH11 . ARG A 1 71  ? -24.09300 0.08900   29.47600 1.000 21.18884 ? 94  ARG A HH11 1 
ATOM   1157 H  HH12 . ARG A 1 71  ? -24.50100 0.10100   28.04300 1.000 21.18884 ? 94  ARG A HH12 1 
ATOM   1158 H  HH21 . ARG A 1 71  ? -23.67000 3.21600   27.38500 1.000 21.53511 ? 94  ARG A HH21 1 
ATOM   1159 H  HH22 . ARG A 1 71  ? -24.24700 1.98000   26.78700 1.000 21.53511 ? 94  ARG A HH22 1 
ATOM   1160 N  N    . VAL A 1 72  ? -18.28900 3.52000   29.84500 1.000 14.99651 ? 95  VAL A N    1 
ATOM   1161 C  CA   . VAL A 1 72  ? -17.10200 4.27200   29.46800 1.000 15.02394 ? 95  VAL A CA   1 
ATOM   1162 C  C    . VAL A 1 72  ? -17.53500 5.39400   28.53100 1.000 14.39097 ? 95  VAL A C    1 
ATOM   1163 O  O    . VAL A 1 72  ? -18.18100 5.13600   27.51100 1.000 14.50551 ? 95  VAL A O    1 
ATOM   1164 C  CB   . VAL A 1 72  ? -16.09400 3.33800   28.76600 1.000 15.57080 ? 95  VAL A CB   1 
ATOM   1165 C  CG1  . VAL A 1 72  ? -14.86300 4.09400   28.33300 1.000 16.88840 ? 95  VAL A CG1  1 
ATOM   1166 C  CG2  . VAL A 1 72  ? -15.71800 2.18400   29.66400 1.000 16.11763 ? 95  VAL A CG2  1 
ATOM   1167 H  H    . VAL A 1 72  ? -18.74400 3.25700   29.16400 1.000 17.99386 ? 95  VAL A H    1 
ATOM   1168 H  HA   . VAL A 1 72  ? -16.68400 4.67400   30.24600 1.000 18.02678 ? 95  VAL A HA   1 
ATOM   1169 H  HB   . VAL A 1 72  ? -16.51700 2.97800   27.97000 1.000 18.68302 ? 95  VAL A HB   1 
ATOM   1170 H  HG11 . VAL A 1 72  ? -14.18500 3.45900   28.05300 1.000 20.26413 ? 95  VAL A HG11 1 
ATOM   1171 H  HG12 . VAL A 1 72  ? -15.09500 4.67800   27.59400 1.000 20.26413 ? 95  VAL A HG12 1 
ATOM   1172 H  HG13 . VAL A 1 72  ? -14.53600 4.61900   29.08000 1.000 20.26413 ? 95  VAL A HG13 1 
ATOM   1173 H  HG21 . VAL A 1 72  ? -15.03600 1.65200   29.22600 1.000 19.33921 ? 95  VAL A HG21 1 
ATOM   1174 H  HG22 . VAL A 1 72  ? -15.37700 2.53400   30.50200 1.000 19.33921 ? 95  VAL A HG22 1 
ATOM   1175 H  HG23 . VAL A 1 72  ? -16.50600 1.64200   29.82800 1.000 19.33921 ? 95  VAL A HG23 1 
ATOM   1176 N  N    . GLU A 1 73  ? -17.17300 6.63400   28.86800 1.000 14.99416 ? 96  GLU A N    1 
ATOM   1177 C  CA   . GLU A 1 73  ? -17.50900 7.77300   28.01900 1.000 15.99949 ? 96  GLU A CA   1 
ATOM   1178 C  C    . GLU A 1 73  ? -16.71500 7.73800   26.71800 1.000 13.90742 ? 96  GLU A C    1 
ATOM   1179 O  O    . GLU A 1 73  ? -15.50900 7.47400   26.71400 1.000 14.99258 ? 96  GLU A O    1 
ATOM   1180 C  CB   . GLU A 1 73  ? -17.17100 9.08700   28.72800 1.000 19.61433 ? 96  GLU A CB   1 
ATOM   1181 C  CG   . GLU A 1 73  ? -17.92500 9.34500   30.01700 1.000 26.01967 ? 96  GLU A CG   1 
ATOM   1182 C  CD   . GLU A 1 73  ? -19.30000 9.94500   29.79900 1.000 32.80846 ? 96  GLU A CD   1 
ATOM   1183 O  OE1  . GLU A 1 73  ? -19.67700 10.18500  28.63000 1.000 36.02513 ? 96  GLU A OE1  1 
ATOM   1184 O  OE2  . GLU A 1 73  ? -20.00600 10.17000  30.80800 1.000 35.41371 ? 96  GLU A OE2  1 
ATOM   1185 H  H    . GLU A 1 73  ? -16.73500 6.83900   29.57900 1.000 17.99104 ? 96  GLU A H    1 
ATOM   1186 H  HA   . GLU A 1 73  ? -18.45900 7.73500   27.82500 1.000 19.19744 ? 96  GLU A HA   1 
ATOM   1187 H  HB2  . GLU A 1 73  ? -16.22500 9.08300   28.94300 1.000 23.53525 ? 96  GLU A HB2  1 
ATOM   1188 H  HB3  . GLU A 1 73  ? -17.37100 9.82000   28.12500 1.000 23.53525 ? 96  GLU A HB3  1 
ATOM   1189 H  HG2  . GLU A 1 73  ? -18.03800 8.50400   30.48700 1.000 31.22166 ? 96  GLU A HG2  1 
ATOM   1190 H  HG3  . GLU A 1 73  ? -17.41300 9.96300   30.56100 1.000 31.22166 ? 96  GLU A HG3  1 
ATOM   1191 N  N    . ILE A 1 74  ? -17.39200 8.03500   25.61200 1.000 14.19449 ? 97  ILE A N    1 
ATOM   1192 C  CA   . ILE A 1 74  ? -16.75800 8.20200   24.30500 1.000 13.94841 ? 97  ILE A CA   1 
ATOM   1193 C  C    . ILE A 1 74  ? -16.83500 9.68100   23.96000 1.000 14.81578 ? 97  ILE A C    1 
ATOM   1194 O  O    . ILE A 1 74  ? -17.93300 10.24000  23.87700 1.000 16.57506 ? 97  ILE A O    1 
ATOM   1195 C  CB   . ILE A 1 74  ? -17.45800 7.37200   23.21900 1.000 15.14289 ? 97  ILE A CB   1 
ATOM   1196 C  CG1  . ILE A 1 74  ? -17.60900 5.90800   23.64500 1.000 15.95947 ? 97  ILE A CG1  1 
ATOM   1197 C  CG2  . ILE A 1 74  ? -16.70700 7.49100   21.89000 1.000 15.90141 ? 97  ILE A CG2  1 
ATOM   1198 C  CD1  . ILE A 1 74  ? -16.33100 5.18200   23.98100 1.000 15.98778 ? 97  ILE A CD1  1 
ATOM   1199 H  H    . ILE A 1 74  ? -18.24500 8.14700   25.59200 1.000 17.03144 ? 97  ILE A H    1 
ATOM   1200 H  HA   . ILE A 1 74  ? -15.83000 7.92300   24.35900 1.000 16.73614 ? 97  ILE A HA   1 
ATOM   1201 H  HB   . ILE A 1 74  ? -18.35200 7.73000   23.09800 1.000 18.16952 ? 97  ILE A HB   1 
ATOM   1202 H  HG12 . ILE A 1 74  ? -18.17100 5.87900   24.43500 1.000 19.14941 ? 97  ILE A HG12 1 
ATOM   1203 H  HG13 . ILE A 1 74  ? -18.03100 5.42400   22.91800 1.000 19.14941 ? 97  ILE A HG13 1 
ATOM   1204 H  HG21 . ILE A 1 74  ? -17.12600 6.90700   21.23700 1.000 19.07974 ? 97  ILE A HG21 1 
ATOM   1205 H  HG22 . ILE A 1 74  ? -16.74800 8.41100   21.58500 1.000 19.07974 ? 97  ILE A HG22 1 
ATOM   1206 H  HG23 . ILE A 1 74  ? -15.78300 7.22700   22.02400 1.000 19.07974 ? 97  ILE A HG23 1 
ATOM   1207 H  HD11 . ILE A 1 74  ? -16.53500 4.25100   24.15900 1.000 19.18339 ? 97  ILE A HD11 1 
ATOM   1208 H  HD12 . ILE A 1 74  ? -15.72200 5.25000   23.22800 1.000 19.18339 ? 97  ILE A HD12 1 
ATOM   1209 H  HD13 . ILE A 1 74  ? -15.93300 5.59000   24.76600 1.000 19.18339 ? 97  ILE A HD13 1 
ATOM   1210 N  N    . LYS A 1 75  ? -15.68300 10.31600  23.77100 1.000 14.55498 ? 98  LYS A N    1 
ATOM   1211 C  CA   . LYS A 1 75  ? -15.59400 11.74100  23.47700 1.000 15.69714 ? 98  LYS A CA   1 
ATOM   1212 C  C    . LYS A 1 75  ? -14.96100 11.95100  22.11000 1.000 13.75216 ? 98  LYS A C    1 
ATOM   1213 O  O    . LYS A 1 75  ? -14.29400 11.06600  21.57100 1.000 13.46902 ? 98  LYS A O    1 
ATOM   1214 C  CB   . LYS A 1 75  ? -14.71300 12.43500  24.51300 1.000 18.42267 ? 98  LYS A CB   1 
ATOM   1215 C  CG   . LYS A 1 75  ? -15.19800 12.27600  25.93100 1.000 21.06978 ? 98  LYS A CG   1 
ATOM   1216 C  CD   . LYS A 1 75  ? -14.13200 12.71900  26.93600 1.000 23.73733 ? 98  LYS A CD   1 
ATOM   1217 C  CE   . LYS A 1 75  ? -12.88800 11.80200  26.93600 1.000 24.14256 ? 98  LYS A CE   1 
ATOM   1218 N  NZ   . LYS A 1 75  ? -13.15400 10.34000  27.26600 1.000 23.39839 ? 98  LYS A NZ   1 
ATOM   1219 H  H    . LYS A 1 75  ? -14.91500 9.93000   23.81000 1.000 17.46402 ? 98  LYS A H    1 
ATOM   1220 H  HA   . LYS A 1 75  ? -16.48400 12.12700  23.47700 1.000 18.83462 ? 98  LYS A HA   1 
ATOM   1221 H  HB2  . LYS A 1 75  ? -13.82000 12.06000  24.46200 1.000 22.10526 ? 98  LYS A HB2  1 
ATOM   1222 H  HB3  . LYS A 1 75  ? -14.68700 13.38400  24.31400 1.000 22.10526 ? 98  LYS A HB3  1 
ATOM   1223 H  HG2  . LYS A 1 75  ? -15.98900 12.82200  26.06400 1.000 25.28178 ? 98  LYS A HG2  1 
ATOM   1224 H  HG3  . LYS A 1 75  ? -15.40600 11.34400  26.09800 1.000 25.28178 ? 98  LYS A HG3  1 
ATOM   1225 H  HD2  . LYS A 1 75  ? -13.84200 13.61700  26.71300 1.000 28.48284 ? 98  LYS A HD2  1 
ATOM   1226 H  HD3  . LYS A 1 75  ? -14.51400 12.70600  27.82800 1.000 28.48284 ? 98  LYS A HD3  1 
ATOM   1227 H  HE2  . LYS A 1 75  ? -12.48700 11.82900  26.05300 1.000 28.96913 ? 98  LYS A HE2  1 
ATOM   1228 H  HE3  . LYS A 1 75  ? -12.26000 12.13700  27.59600 1.000 28.96913 ? 98  LYS A HE3  1 
ATOM   1229 H  HZ1  . LYS A 1 75  ? -12.38800 9.88900   27.29200 1.000 28.07612 ? 98  LYS A HZ1  1 
ATOM   1230 H  HZ2  . LYS A 1 75  ? -13.55400 10.27500  28.05900 1.000 28.07612 ? 98  LYS A HZ2  1 
ATOM   1231 H  HZ3  . LYS A 1 75  ? -13.68100 9.97900   26.64700 1.000 28.07612 ? 98  LYS A HZ3  1 
ATOM   1232 N  N    . LYS A 1 76  ? -15.14600 13.15100  21.55500 1.000 14.19442 ? 99  LYS A N    1 
ATOM   1233 C  CA   . LYS A 1 76  ? -14.47200 13.45800  20.29800 1.000 15.86975 ? 99  LYS A CA   1 
ATOM   1234 C  C    . LYS A 1 76  ? -12.97000 13.27900  20.44000 1.000 14.09368 ? 99  LYS A C    1 
ATOM   1235 O  O    . LYS A 1 76  ? -12.30100 12.81400  19.50900 1.000 14.33943 ? 99  LYS A O    1 
ATOM   1236 C  CB   . LYS A 1 76  ? -14.80100 14.88100  19.84600 1.000 20.37052 ? 99  LYS A CB   1 
ATOM   1237 C  CG   . LYS A 1 76  ? -15.87000 14.93500  18.78300 1.000 26.34918 ? 99  LYS A CG   1 
ATOM   1238 C  CD   . LYS A 1 76  ? -16.13000 16.35300  18.31200 1.000 31.61255 ? 99  LYS A CD   1 
ATOM   1239 C  CE   . LYS A 1 76  ? -17.24600 16.39800  17.28900 1.000 35.61833 ? 99  LYS A CE   1 
ATOM   1240 N  NZ   . LYS A 1 76  ? -16.92300 15.59900  16.07100 1.000 37.58605 ? 99  LYS A NZ   1 
ATOM   1241 H  H    . LYS A 1 76  ? -15.63800 13.77900  21.87500 1.000 17.03135 ? 99  LYS A H    1 
ATOM   1242 H  HA   . LYS A 1 76  ? -14.79400 12.85200  19.61300 1.000 19.04175 ? 99  LYS A HA   1 
ATOM   1243 H  HB2  . LYS A 1 76  ? -15.11500 15.38900  20.61000 1.000 24.44267 ? 99  LYS A HB2  1 
ATOM   1244 H  HB3  . LYS A 1 76  ? -13.99900 15.28800  19.48300 1.000 24.44267 ? 99  LYS A HB3  1 
ATOM   1245 H  HG2  . LYS A 1 76  ? -15.58700 14.41000  18.01800 1.000 31.61706 ? 99  LYS A HG2  1 
ATOM   1246 H  HG3  . LYS A 1 76  ? -16.69700 14.57900  19.14300 1.000 31.61706 ? 99  LYS A HG3  1 
ATOM   1247 H  HD2  . LYS A 1 76  ? -16.38800 16.90100  19.07000 1.000 37.93311 ? 99  LYS A HD2  1 
ATOM   1248 H  HD3  . LYS A 1 76  ? -15.32600 16.70900  17.90400 1.000 37.93311 ? 99  LYS A HD3  1 
ATOM   1249 H  HE2  . LYS A 1 76  ? -18.05500 16.03600  17.68300 1.000 42.74005 ? 99  LYS A HE2  1 
ATOM   1250 H  HE3  . LYS A 1 76  ? -17.39200 17.31800  17.01700 1.000 42.74005 ? 99  LYS A HE3  1 
ATOM   1251 H  HZ1  . LYS A 1 76  ? -16.05000 15.63600  15.90500 1.000 45.10131 ? 99  LYS A HZ1  1 
ATOM   1252 H  HZ2  . LYS A 1 76  ? -17.15800 14.74900  16.19300 1.000 45.10131 ? 99  LYS A HZ2  1 
ATOM   1253 H  HZ3  . LYS A 1 76  ? -17.36500 15.92200  15.36900 1.000 45.10131 ? 99  LYS A HZ3  1 
ATOM   1254 N  N    . SER A 1 77  ? -12.42500 13.63700  21.60400 1.000 14.23060 ? 100 SER A N    1 
ATOM   1255 C  CA   . SER A 1 77  ? -10.99800 13.51900  21.85500 1.000 14.87269 ? 100 SER A CA   1 
ATOM   1256 C  C    . SER A 1 77  ? -10.51700 12.07900  21.90700 1.000 13.56880 ? 100 SER A C    1 
ATOM   1257 O  O    . SER A 1 77  ? -9.30400  11.85800  21.86600 1.000 14.87793 ? 100 SER A O    1 
ATOM   1258 C  CB   . SER A 1 77  ? -10.62700 14.22600  23.15800 1.000 15.41282 ? 100 SER A CB   1 
ATOM   1259 O  OG   . SER A 1 77  ? -11.29300 13.63900  24.25400 1.000 17.33835 ? 100 SER A OG   1 
ATOM   1260 H  H    . SER A 1 77  ? -12.86900 13.95300  22.26900 1.000 17.07477 ? 100 SER A H    1 
ATOM   1261 H  HA   . SER A 1 77  ? -10.53000 13.96100  21.12900 1.000 17.84528 ? 100 SER A HA   1 
ATOM   1262 H  HB2  . SER A 1 77  ? -9.66900  14.15400  23.29400 1.000 18.49344 ? 100 SER A HB2  1 
ATOM   1263 H  HB3  . SER A 1 77  ? -10.88400 15.15900  23.09500 1.000 18.49344 ? 100 SER A HB3  1 
ATOM   1264 H  HG   . SER A 1 77  ? -11.00300 12.86100  24.38300 1.000 20.80407 ? 100 SER A HG   1 
ATOM   1265 N  N    . ASP A 1 78  ? -11.42400 11.10500  21.97500 1.000 13.04413 ? 101 ASP A N    1 
ATOM   1266 C  CA   . ASP A 1 78  ? -11.04000 9.70100   21.93500 1.000 11.79431 ? 101 ASP A CA   1 
ATOM   1267 C  C    . ASP A 1 78  ? -10.87300 9.17800   20.51900 1.000 11.86434 ? 101 ASP A C    1 
ATOM   1268 O  O    . ASP A 1 78  ? -10.26400 8.12100   20.32500 1.000 12.87400 ? 101 ASP A O    1 
ATOM   1269 C  CB   . ASP A 1 78  ? -12.10600 8.84700   22.61100 1.000 12.31177 ? 101 ASP A CB   1 
ATOM   1270 C  CG   . ASP A 1 78  ? -12.14800 9.03500   24.10600 1.000 12.75401 ? 101 ASP A CG   1 
ATOM   1271 O  OD1  . ASP A 1 78  ? -11.08600 8.94900   24.73700 1.000 14.24746 ? 101 ASP A OD1  1 
ATOM   1272 O  OD2  . ASP A 1 78  ? -13.25400 9.22700   24.65600 1.000 14.06863 ? 101 ASP A OD2  1 
ATOM   1273 H  H    . ASP A 1 78  ? -12.27100 11.23500  22.04500 1.000 15.65101 ? 101 ASP A H    1 
ATOM   1274 H  HA   . ASP A 1 78  ? -10.20100 9.60900   22.41300 1.000 14.15123 ? 101 ASP A HA   1 
ATOM   1275 H  HB2  . ASP A 1 78  ? -12.97500 9.08700   22.25400 1.000 14.77217 ? 101 ASP A HB2  1 
ATOM   1276 H  HB3  . ASP A 1 78  ? -11.92100 7.91200   22.43200 1.000 14.77217 ? 101 ASP A HB3  1 
ATOM   1277 N  N    . LEU A 1 79  ? -11.41500 9.86600   19.52600 1.000 11.65418 ? 102 LEU A N    1 
ATOM   1278 C  CA   . LEU A 1 79  ? -11.36700 9.33000   18.17500 1.000 11.80541 ? 102 LEU A CA   1 
ATOM   1279 C  C    . LEU A 1 79  ? -9.92600  9.21900   17.70600 1.000 12.32854 ? 102 LEU A C    1 
ATOM   1280 O  O    . LEU A 1 79  ? -9.08600  10.08000  17.98700 1.000 13.27695 ? 102 LEU A O    1 
ATOM   1281 C  CB   . LEU A 1 79  ? -12.18300 10.20600  17.22700 1.000 13.00015 ? 102 LEU A CB   1 
ATOM   1282 C  CG   . LEU A 1 79  ? -13.68200 10.24700  17.52000 1.000 13.44276 ? 102 LEU A CG   1 
ATOM   1283 C  CD1  . LEU A 1 79  ? -14.35300 11.26900  16.60500 1.000 15.66174 ? 102 LEU A CD1  1 
ATOM   1284 C  CD2  . LEU A 1 79  ? -14.31000 8.89300   17.35700 1.000 14.74201 ? 102 LEU A CD2  1 
ATOM   1285 H  H    . LEU A 1 79  ? -11.80700 10.62800  19.60500 1.000 13.98307 ? 102 LEU A H    1 
ATOM   1286 H  HA   . LEU A 1 79  ? -11.75800 8.44300   18.16000 1.000 14.16455 ? 102 LEU A HA   1 
ATOM   1287 H  HB2  . LEU A 1 79  ? -11.85000 11.11500  17.28600 1.000 15.59823 ? 102 LEU A HB2  1 
ATOM   1288 H  HB3  . LEU A 1 79  ? -12.07100 9.86900   16.32500 1.000 15.59823 ? 102 LEU A HB3  1 
ATOM   1289 H  HG   . LEU A 1 79  ? -13.82000 10.51200  18.44300 1.000 16.12936 ? 102 LEU A HG   1 
ATOM   1290 H  HD11 . LEU A 1 79  ? -15.30700 11.27000  16.77800 1.000 18.79214 ? 102 LEU A HD11 1 
ATOM   1291 H  HD12 . LEU A 1 79  ? -13.98300 12.14700  16.78800 1.000 18.79214 ? 102 LEU A HD12 1 
ATOM   1292 H  HD13 . LEU A 1 79  ? -14.18400 11.02500  15.68100 1.000 18.79214 ? 102 LEU A HD13 1 
ATOM   1293 H  HD21 . LEU A 1 79  ? -15.27400 8.98200   17.42200 1.000 17.68846 ? 102 LEU A HD21 1 
ATOM   1294 H  HD22 . LEU A 1 79  ? -14.06900 8.53600   16.48800 1.000 17.68846 ? 102 LEU A HD22 1 
ATOM   1295 H  HD23 . LEU A 1 79  ? -13.98400 8.30700   18.05800 1.000 17.68846 ? 102 LEU A HD23 1 
ATOM   1296 N  N    . VAL A 1 80  ? -9.64400  8.13900   16.99000 1.000 13.20753 ? 103 VAL A N    1 
ATOM   1297 C  CA   . VAL A 1 80  ? -8.33800  7.92700   16.38600 1.000 14.03969 ? 103 VAL A CA   1 
ATOM   1298 C  C    . VAL A 1 80  ? -8.57000  7.71500   14.88700 1.000 14.88315 ? 103 VAL A C    1 
ATOM   1299 O  O    . VAL A 1 80  ? -9.41200  8.40000   14.29900 1.000 17.12254 ? 103 VAL A O    1 
ATOM   1300 C  CB   . VAL A 1 80  ? -7.55400  6.81100   17.10500 1.000 14.85531 ? 103 VAL A CB   1 
ATOM   1301 C  CG1  . VAL A 1 80  ? -7.14100  7.27500   18.51600 1.000 15.91244 ? 103 VAL A CG1  1 
ATOM   1302 C  CG2  . VAL A 1 80  ? -8.34100  5.53100   17.21200 1.000 15.84894 ? 103 VAL A CG2  1 
ATOM   1303 H  H    . VAL A 1 80  ? -10.20300 7.50400   16.83600 1.000 15.84709 ? 103 VAL A H    1 
ATOM   1304 H  HA   . VAL A 1 80  ? -7.76400  8.70400   16.47300 1.000 16.84568 ? 103 VAL A HA   1 
ATOM   1305 H  HB   . VAL A 1 80  ? -6.76400  6.62500   16.57400 1.000 17.82443 ? 103 VAL A HB   1 
ATOM   1306 H  HG11 . VAL A 1 80  ? -6.61300  6.57900   18.93600 1.000 19.09297 ? 103 VAL A HG11 1 
ATOM   1307 H  HG12 . VAL A 1 80  ? -6.61600  8.08800   18.43900 1.000 19.09297 ? 103 VAL A HG12 1 
ATOM   1308 H  HG13 . VAL A 1 80  ? -7.94000  7.44600   19.03800 1.000 19.09297 ? 103 VAL A HG13 1 
ATOM   1309 H  HG21 . VAL A 1 80  ? -7.80400  4.86700   17.67100 1.000 19.01677 ? 103 VAL A HG21 1 
ATOM   1310 H  HG22 . VAL A 1 80  ? -9.15500  5.70200   17.71100 1.000 19.01677 ? 103 VAL A HG22 1 
ATOM   1311 H  HG23 . VAL A 1 80  ? -8.56000  5.22000   16.31900 1.000 19.01677 ? 103 VAL A HG23 1 
ATOM   1312 N  N    . ASN A 1 81  ? -7.85500  6.78100   14.26200 1.000 17.09253 ? 104 ASN A N    1 
ATOM   1313 C  CA   . ASN A 1 81  ? -7.84900  6.66300   12.80900 1.000 19.08692 ? 104 ASN A CA   1 
ATOM   1314 C  C    . ASN A 1 81  ? -8.88400  5.69900   12.25000 1.000 20.52871 ? 104 ASN A C    1 
ATOM   1315 O  O    . ASN A 1 81  ? -9.14400  5.72500   11.04400 1.000 25.31902 ? 104 ASN A O    1 
ATOM   1316 C  CB   . ASN A 1 81  ? -6.45800  6.22900   12.32200 1.000 19.98271 ? 104 ASN A CB   1 
ATOM   1317 C  CG   . ASN A 1 81  ? -5.98900  4.87300   12.91000 1.000 20.66687 ? 104 ASN A CG   1 
ATOM   1318 O  OD1  . ASN A 1 81  ? -6.45900  4.39100   13.99300 1.000 17.85310 ? 104 ASN A OD1  1 
ATOM   1319 N  ND2  . ASN A 1 81  ? -5.01300  4.26200   12.20500 1.000 21.53207 ? 104 ASN A ND2  1 
ATOM   1320 H  H    . ASN A 1 81  ? -7.36200  6.20000   14.66200 1.000 20.50909 ? 104 ASN A H    1 
ATOM   1321 H  HA   . ASN A 1 81  ? -8.05100  7.53900   12.44400 1.000 22.90235 ? 104 ASN A HA   1 
ATOM   1322 H  HB2  . ASN A 1 81  ? -6.47800  6.14200   11.35600 1.000 23.97730 ? 104 ASN A HB2  1 
ATOM   1323 H  HB3  . ASN A 1 81  ? -5.81200  6.90400   12.58000 1.000 23.97730 ? 104 ASN A HB3  1 
ATOM   1324 H  HD21 . ASN A 1 81  ? -4.70000  3.50600   12.47000 1.000 25.83653 ? 104 ASN A HD21 1 
ATOM   1325 H  HD22 . ASN A 1 81  ? -4.70300  4.63000   11.49200 1.000 25.83653 ? 104 ASN A HD22 1 
ATOM   1326 N  N    . TYR A 1 82  ? -9.45800  4.83900   13.06800 1.000 15.65689 ? 105 TYR A N    1 
ATOM   1327 C  CA   . TYR A 1 82  ? -10.39100 3.82100   12.58700 1.000 15.26837 ? 105 TYR A CA   1 
ATOM   1328 C  C    . TYR A 1 82  ? -11.35900 3.53800   13.73500 1.000 13.68739 ? 105 TYR A C    1 
ATOM   1329 O  O    . TYR A 1 82  ? -11.02600 2.81000   14.67500 1.000 14.21124 ? 105 TYR A O    1 
ATOM   1330 C  CB   . TYR A 1 82  ? -9.66500  2.56000   12.14200 1.000 16.40797 ? 105 TYR A CB   1 
ATOM   1331 C  CG   . TYR A 1 82  ? -10.58000 1.58400   11.44800 1.000 17.36317 ? 105 TYR A CG   1 
ATOM   1332 C  CD1  . TYR A 1 82  ? -11.15600 1.91100   10.23700 1.000 19.65188 ? 105 TYR A CD1  1 
ATOM   1333 C  CD2  . TYR A 1 82  ? -10.89500 0.35300   12.00700 1.000 16.95739 ? 105 TYR A CD2  1 
ATOM   1334 C  CE1  . TYR A 1 82  ? -12.00000 1.04700   9.59400  1.000 20.96644 ? 105 TYR A CE1  1 
ATOM   1335 C  CE2  . TYR A 1 82  ? -11.74600 -0.52800  11.36200 1.000 18.42876 ? 105 TYR A CE2  1 
ATOM   1336 C  CZ   . TYR A 1 82  ? -12.29900 -0.16900  10.15400 1.000 21.52314 ? 105 TYR A CZ   1 
ATOM   1337 O  OH   . TYR A 1 82  ? -13.15300 -1.02500  9.48100  1.000 24.20839 ? 105 TYR A OH   1 
ATOM   1338 H  H    . TYR A 1 82  ? -9.32600  4.81700   13.91800 1.000 18.78632 ? 105 TYR A H    1 
ATOM   1339 H  HA   . TYR A 1 82  ? -10.88700 4.16400   11.82700 1.000 18.32009 ? 105 TYR A HA   1 
ATOM   1340 H  HB2  . TYR A 1 82  ? -8.95800  2.80300   11.52400 1.000 19.68761 ? 105 TYR A HB2  1 
ATOM   1341 H  HB3  . TYR A 1 82  ? -9.28800  2.12000   12.92000 1.000 19.68761 ? 105 TYR A HB3  1 
ATOM   1342 H  HD1  . TYR A 1 82  ? -10.96600 2.73500   9.85000  1.000 23.58031 ? 105 TYR A HD1  1 
ATOM   1343 H  HD2  . TYR A 1 82  ? -10.52800 0.11600   12.82800 1.000 20.34692 ? 105 TYR A HD2  1 
ATOM   1344 H  HE1  . TYR A 1 82  ? -12.37200 1.28500   8.77500  1.000 25.15778 ? 105 TYR A HE1  1 
ATOM   1345 H  HE2  . TYR A 1 82  ? -11.94200 -1.35400  11.74200 1.000 22.11256 ? 105 TYR A HE2  1 
ATOM   1346 H  HH   . TYR A 1 82  ? -13.42800 -1.62500  10.00100 1.000 29.04812 ? 105 TYR A HH   1 
ATOM   1347 N  N    . ASN A 1 83  ? -12.55900 4.11100   13.62300 1.000 13.79344 ? 106 ASN A N    1 
ATOM   1348 C  CA   . ASN A 1 83  ? -13.51800 4.18700   14.72300 1.000 15.22591 ? 106 ASN A CA   1 
ATOM   1349 C  C    . ASN A 1 83  ? -14.91500 3.77900   14.25400 1.000 13.74227 ? 106 ASN A C    1 
ATOM   1350 O  O    . ASN A 1 83  ? -15.88600 4.49300   14.50000 1.000 15.02620 ? 106 ASN A O    1 
ATOM   1351 C  CB   . ASN A 1 83  ? -13.57700 5.61900   15.27600 1.000 17.01098 ? 106 ASN A CB   1 
ATOM   1352 C  CG   . ASN A 1 83  ? -12.24800 6.35400   15.21000 1.000 17.31065 ? 106 ASN A CG   1 
ATOM   1353 O  OD1  . ASN A 1 83  ? -11.29700 5.99600   15.87500 1.000 17.06085 ? 106 ASN A OD1  1 
ATOM   1354 N  ND2  . ASN A 1 83  ? -12.19200 7.41600   14.40900 1.000 17.95029 ? 106 ASN A ND2  1 
ATOM   1355 H  H    . ASN A 1 83  ? -12.84700 4.47400   12.89800 1.000 16.55018 ? 106 ASN A H    1 
ATOM   1356 H  HA   . ASN A 1 83  ? -13.23000 3.57800   15.42100 1.000 18.26914 ? 106 ASN A HA   1 
ATOM   1357 H  HB2  . ASN A 1 83  ? -14.22200 6.12700   14.75900 1.000 20.41122 ? 106 ASN A HB2  1 
ATOM   1358 H  HB3  . ASN A 1 83  ? -13.85000 5.58400   16.20600 1.000 20.41122 ? 106 ASN A HB3  1 
ATOM   1359 H  HD21 . ASN A 1 83  ? -11.46200 7.86400   14.33900 1.000 21.53840 ? 106 ASN A HD21 1 
ATOM   1360 H  HD22 . ASN A 1 83  ? -12.88700 7.65400   13.96200 1.000 21.53840 ? 106 ASN A HD22 1 
ATOM   1361 N  N    . PRO A 1 84  ? -15.05400 2.63800   13.56100 1.000 13.82431 ? 107 PRO A N    1 
ATOM   1362 C  CA   . PRO A 1 84  ? -16.34000 2.31200   12.91300 1.000 16.31240 ? 107 PRO A CA   1 
ATOM   1363 C  C    . PRO A 1 84  ? -17.52500 2.22900   13.85800 1.000 15.58684 ? 107 PRO A C    1 
ATOM   1364 O  O    . PRO A 1 84  ? -18.65000 2.54800   13.45400 1.000 17.37220 ? 107 PRO A O    1 
ATOM   1365 C  CB   . PRO A 1 84  ? -16.05300 0.94700   12.26100 1.000 18.16760 ? 107 PRO A CB   1 
ATOM   1366 C  CG   . PRO A 1 84  ? -14.88000 0.40500   13.01400 1.000 17.42246 ? 107 PRO A CG   1 
ATOM   1367 C  CD   . PRO A 1 84  ? -14.04800 1.59200   13.31400 1.000 14.31061 ? 107 PRO A CD   1 
ATOM   1368 H  HA   . PRO A 1 84  ? -16.53300 2.97900   12.23500 1.000 19.57293 ? 107 PRO A HA   1 
ATOM   1369 H  HB2  . PRO A 1 84  ? -16.82500 0.36700   12.35300 1.000 21.79917 ? 107 PRO A HB2  1 
ATOM   1370 H  HB3  . PRO A 1 84  ? -15.83900 1.06700   11.32200 1.000 21.79917 ? 107 PRO A HB3  1 
ATOM   1371 H  HG2  . PRO A 1 84  ? -15.17900 -0.02600  13.83000 1.000 20.90500 ? 107 PRO A HG2  1 
ATOM   1372 H  HG3  . PRO A 1 84  ? -14.39500 -0.23000  12.46300 1.000 20.90500 ? 107 PRO A HG3  1 
ATOM   1373 H  HD2  . PRO A 1 84  ? -13.50100 1.44400   14.10200 1.000 17.17078 ? 107 PRO A HD2  1 
ATOM   1374 H  HD3  . PRO A 1 84  ? -13.48500 1.82200   12.55900 1.000 17.17078 ? 107 PRO A HD3  1 
ATOM   1375 N  N    . ILE A 1 85  ? -17.31700 1.77700   15.08700 1.000 14.07662 ? 108 ILE A N    1 
ATOM   1376 C  CA   . ILE A 1 85  ? -18.37400 1.70700   16.08400 1.000 13.77926 ? 108 ILE A CA   1 
ATOM   1377 C  C    . ILE A 1 85  ? -18.36300 2.92700   16.99400 1.000 13.79269 ? 108 ILE A C    1 
ATOM   1378 O  O    . ILE A 1 85  ? -19.39600 3.55700   17.20100 1.000 15.18432 ? 108 ILE A O    1 
ATOM   1379 C  CB   . ILE A 1 85  ? -18.26300 0.39300   16.89200 1.000 14.15635 ? 108 ILE A CB   1 
ATOM   1380 C  CG1  . ILE A 1 85  ? -18.28000 -0.82200  15.95100 1.000 14.51010 ? 108 ILE A CG1  1 
ATOM   1381 C  CG2  . ILE A 1 85  ? -19.35700 0.34400   17.94700 1.000 15.13416 ? 108 ILE A CG2  1 
ATOM   1382 C  CD1  . ILE A 1 85  ? -19.50500 -0.94100  15.04600 1.000 16.37783 ? 108 ILE A CD1  1 
ATOM   1383 H  H    . ILE A 1 85  ? -16.55600 1.49800   15.37300 1.000 16.89000 ? 108 ILE A H    1 
ATOM   1384 H  HA   . ILE A 1 85  ? -19.22900 1.69600   15.62500 1.000 16.53316 ? 108 ILE A HA   1 
ATOM   1385 H  HB   . ILE A 1 85  ? -17.41200 0.36700   17.35700 1.000 16.98567 ? 108 ILE A HB   1 
ATOM   1386 H  HG12 . ILE A 1 85  ? -17.50100 -0.77300  15.37600 1.000 17.41017 ? 108 ILE A HG12 1 
ATOM   1387 H  HG13 . ILE A 1 85  ? -18.24300 -1.62600  16.49200 1.000 17.41017 ? 108 ILE A HG13 1 
ATOM   1388 H  HG21 . ILE A 1 85  ? -19.33700 -0.52300  18.38200 1.000 18.15904 ? 108 ILE A HG21 1 
ATOM   1389 H  HG22 . ILE A 1 85  ? -19.19900 1.04500   18.59900 1.000 18.15904 ? 108 ILE A HG22 1 
ATOM   1390 H  HG23 . ILE A 1 85  ? -20.21600 0.47900   17.51700 1.000 18.15904 ? 108 ILE A HG23 1 
ATOM   1391 H  HD11 . ILE A 1 85  ? -19.45200 -1.77400  14.55100 1.000 19.65145 ? 108 ILE A HD11 1 
ATOM   1392 H  HD12 . ILE A 1 85  ? -20.30500 -0.93200  15.59400 1.000 19.65145 ? 108 ILE A HD12 1 
ATOM   1393 H  HD13 . ILE A 1 85  ? -19.51700 -0.19100  14.43000 1.000 19.65145 ? 108 ILE A HD13 1 
ATOM   1394 N  N    . ALA A 1 86  ? -17.19300 3.29000   17.51500 1.000 13.44699 ? 109 ALA A N    1 
ATOM   1395 C  CA   . ALA A 1 86  ? -17.12800 4.38300   18.48000 1.000 14.15647 ? 109 ALA A CA   1 
ATOM   1396 C  C    . ALA A 1 86  ? -17.62800 5.70100   17.90100 1.000 14.88874 ? 109 ALA A C    1 
ATOM   1397 O  O    . ALA A 1 86  ? -18.18400 6.52000   18.64000 1.000 15.71362 ? 109 ALA A O    1 
ATOM   1398 C  CB   . ALA A 1 86  ? -15.70200 4.54300   18.99800 1.000 14.89047 ? 109 ALA A CB   1 
ATOM   1399 H  H    . ALA A 1 86  ? -16.43600 2.92700   17.33000 1.000 16.13443 ? 109 ALA A H    1 
ATOM   1400 H  HA   . ALA A 1 86  ? -17.70200 4.15600   19.22800 1.000 16.98581 ? 109 ALA A HA   1 
ATOM   1401 H  HB1  . ALA A 1 86  ? -15.67600 5.28000   19.62800 1.000 17.86661 ? 109 ALA A HB1  1 
ATOM   1402 H  HB2  . ALA A 1 86  ? -15.43200 3.72200   19.43900 1.000 17.86661 ? 109 ALA A HB2  1 
ATOM   1403 H  HB3  . ALA A 1 86  ? -15.11200 4.72600   18.25000 1.000 17.86661 ? 109 ALA A HB3  1 
ATOM   1404 N  N    . GLU A 1 87  ? -17.42700 5.94300   16.59600 1.000 15.84593 ? 110 GLU A N    1 
ATOM   1405 C  CA   . GLU A 1 87  ? -17.87700 7.20600   16.01600 1.000 17.81698 ? 110 GLU A CA   1 
ATOM   1406 C  C    . GLU A 1 87  ? -19.39100 7.36300   16.10000 1.000 18.54384 ? 110 GLU A C    1 
ATOM   1407 O  O    . GLU A 1 87  ? -19.89100 8.48600   15.98100 1.000 21.08425 ? 110 GLU A O    1 
ATOM   1408 C  CB   . GLU A 1 87  ? -17.39400 7.36400   14.56600 1.000 19.12079 ? 110 GLU A CB   1 
ATOM   1409 C  CG   . GLU A 1 87  ? -18.11900 6.48200   13.56100 1.000 20.50666 ? 110 GLU A CG   1 
ATOM   1410 C  CD   . GLU A 1 87  ? -17.61200 6.64300   12.13100 1.000 23.78923 ? 110 GLU A CD   1 
ATOM   1411 O  OE1  . GLU A 1 87  ? -16.64400 7.39100   11.90500 1.000 25.97313 ? 110 GLU A OE1  1 
ATOM   1412 O  OE2  . GLU A 1 87  ? -18.19100 6.01600   11.22500 1.000 26.38919 ? 110 GLU A OE2  1 
ATOM   1413 H  H    . GLU A 1 87  ? -17.04300 5.40500   16.04600 1.000 19.01316 ? 110 GLU A H    1 
ATOM   1414 H  HA   . GLU A 1 87  ? -17.47200 7.93000   16.51800 1.000 21.37842 ? 110 GLU A HA   1 
ATOM   1415 H  HB2  . GLU A 1 87  ? -17.52600 8.28600   14.29600 1.000 22.94300 ? 110 GLU A HB2  1 
ATOM   1416 H  HB3  . GLU A 1 87  ? -16.45200 7.13900   14.52800 1.000 22.94300 ? 110 GLU A HB3  1 
ATOM   1417 H  HG2  . GLU A 1 87  ? -17.99800 5.55400   13.81600 1.000 24.60604 ? 110 GLU A HG2  1 
ATOM   1418 H  HG3  . GLU A 1 87  ? -19.06200 6.70800   13.56900 1.000 24.60604 ? 110 GLU A HG3  1 
ATOM   1419 N  N    . LYS A 1 88  ? -20.13100 6.27100   16.28800 1.000 17.97042 ? 111 LYS A N    1 
ATOM   1420 C  CA   . LYS A 1 88  ? -21.57900 6.32200   16.43300 1.000 19.69497 ? 111 LYS A CA   1 
ATOM   1421 C  C    . LYS A 1 88  ? -22.02600 6.60300   17.86000 1.000 19.26943 ? 111 LYS A C    1 
ATOM   1422 O  O    . LYS A 1 88  ? -23.22600 6.77200   18.09500 1.000 21.70453 ? 111 LYS A O    1 
ATOM   1423 C  CB   . LYS A 1 88  ? -22.18600 4.97500   16.04300 1.000 22.28450 ? 111 LYS A CB   1 
ATOM   1424 C  CG   . LYS A 1 88  ? -21.83800 4.47400   14.67400 1.000 26.47962 ? 111 LYS A CG   1 
ATOM   1425 C  CD   . LYS A 1 88  ? -22.52300 3.13100   14.47400 1.000 30.28610 ? 111 LYS A CD   1 
ATOM   1426 C  CE   . LYS A 1 88  ? -22.01000 2.39600   13.26900 1.000 33.87562 ? 111 LYS A CE   1 
ATOM   1427 N  NZ   . LYS A 1 88  ? -22.63100 1.04700   13.19700 1.000 36.37774 ? 111 LYS A NZ   1 
ATOM   1428 H  H    . LYS A 1 88  ? -19.80800 5.47500   16.33600 1.000 21.56255 ? 111 LYS A H    1 
ATOM   1429 H  HA   . LYS A 1 88  ? -21.91100 7.01900   15.84700 1.000 23.63201 ? 111 LYS A HA   1 
ATOM   1430 H  HB2  . LYS A 1 88  ? -21.88100 4.30900   16.67900 1.000 26.73945 ? 111 LYS A HB2  1 
ATOM   1431 H  HB3  . LYS A 1 88  ? -23.15200 5.05500   16.08300 1.000 26.73945 ? 111 LYS A HB3  1 
ATOM   1432 H  HG2  . LYS A 1 88  ? -22.15400 5.09600   14.00000 1.000 31.77360 ? 111 LYS A HG2  1 
ATOM   1433 H  HG3  . LYS A 1 88  ? -20.87900 4.35700   14.59400 1.000 31.77360 ? 111 LYS A HG3  1 
ATOM   1434 H  HD2  . LYS A 1 88  ? -22.36600 2.57600   15.25400 1.000 36.34137 ? 111 LYS A HD2  1 
ATOM   1435 H  HD3  . LYS A 1 88  ? -23.47500 3.27500   14.35600 1.000 36.34137 ? 111 LYS A HD3  1 
ATOM   1436 H  HE2  . LYS A 1 88  ? -22.23700 2.88800   12.46400 1.000 40.64879 ? 111 LYS A HE2  1 
ATOM   1437 H  HE3  . LYS A 1 88  ? -21.04700 2.29300   13.33300 1.000 40.64879 ? 111 LYS A HE3  1 
ATOM   1438 H  HZ1  . LYS A 1 88  ? -22.16600 0.52700   12.64500 1.000 43.65134 ? 111 LYS A HZ1  1 
ATOM   1439 H  HZ2  . LYS A 1 88  ? -22.64200 0.67400   14.00500 1.000 43.65134 ? 111 LYS A HZ2  1 
ATOM   1440 H  HZ3  . LYS A 1 88  ? -23.46700 1.11200   12.89800 1.000 43.65134 ? 111 LYS A HZ3  1 
ATOM   1441 N  N    . HIS A 1 89  ? -21.09800 6.62800   18.81600 1.000 18.68787 ? 112 HIS A N    1 
ATOM   1442 C  CA   . HIS A 1 89  ? -21.42000 6.75700   20.23200 1.000 18.91254 ? 112 HIS A CA   1 
ATOM   1443 C  C    . HIS A 1 89  ? -20.76400 7.97100   20.87000 1.000 17.15930 ? 112 HIS A C    1 
ATOM   1444 O  O    . HIS A 1 89  ? -20.73500 8.07600   22.10200 1.000 17.61072 ? 112 HIS A O    1 
ATOM   1445 C  CB   . HIS A 1 89  ? -21.01200 5.48200   20.97700 1.000 19.35809 ? 112 HIS A CB   1 
ATOM   1446 C  CG   . HIS A 1 89  ? -21.77700 4.27700   20.54700 1.000 20.51200 ? 112 HIS A CG   1 
ATOM   1447 N  ND1  . HIS A 1 89  ? -22.92200 3.86200   21.18900 1.000 22.28270 ? 112 HIS A ND1  1 
ATOM   1448 C  CD2  . HIS A 1 89  ? -21.57400 3.40300   19.53200 1.000 20.10525 ? 112 HIS A CD2  1 
ATOM   1449 C  CE1  . HIS A 1 89  ? -23.39600 2.78600   20.58400 1.000 22.05247 ? 112 HIS A CE1  1 
ATOM   1450 N  NE2  . HIS A 1 89  ? -22.60100 2.49300   19.57000 1.000 21.44581 ? 112 HIS A NE2  1 
ATOM   1451 H  H    . HIS A 1 89  ? -20.25400 6.57000   18.66300 1.000 22.42349 ? 112 HIS A H    1 
ATOM   1452 H  HA   . HIS A 1 89  ? -22.37900 6.86600   20.32600 1.000 22.69309 ? 112 HIS A HA   1 
ATOM   1453 H  HB2  . HIS A 1 89  ? -20.07100 5.31200   20.81500 1.000 23.22776 ? 112 HIS A HB2  1 
ATOM   1454 H  HB3  . HIS A 1 89  ? -21.16700 5.61100   21.92600 1.000 23.22776 ? 112 HIS A HB3  1 
ATOM   1455 H  HD2  . HIS A 1 89  ? -20.87000 3.41600   18.92400 1.000 24.12435 ? 112 HIS A HD2  1 
ATOM   1456 H  HE1  . HIS A 1 89  ? -24.15900 2.31500   20.83100 1.000 26.46101 ? 112 HIS A HE1  1 
ATOM   1457 H  HE2  . HIS A 1 89  ? -22.71000 1.83900   19.02200 1.000 25.73303 ? 112 HIS A HE2  1 
ATOM   1458 N  N    . VAL A 1 90  ? -20.24300 8.89800   20.07100 1.000 17.82802 ? 113 VAL A N    1 
ATOM   1459 C  CA   . VAL A 1 90  ? -19.61000 10.08200  20.63700 1.000 16.89571 ? 113 VAL A CA   1 
ATOM   1460 C  C    . VAL A 1 90  ? -20.61500 10.84000  21.49300 1.000 16.67467 ? 113 VAL A C    1 
ATOM   1461 O  O    . VAL A 1 90  ? -21.77100 11.04400  21.10300 1.000 17.34947 ? 113 VAL A O    1 
ATOM   1462 C  CB   . VAL A 1 90  ? -19.01000 10.94300  19.51800 1.000 17.94238 ? 113 VAL A CB   1 
ATOM   1463 C  CG1  . VAL A 1 90  ? -18.51000 12.27500  20.06300 1.000 19.49282 ? 113 VAL A CG1  1 
ATOM   1464 C  CG2  . VAL A 1 90  ? -17.87200 10.19000  18.82900 1.000 20.12224 ? 113 VAL A CG2  1 
ATOM   1465 H  H    . VAL A 1 90  ? -20.24300 8.86500   19.21200 1.000 21.39167 ? 113 VAL A H    1 
ATOM   1466 H  HA   . VAL A 1 90  ? -18.88300 9.81500   21.22100 1.000 20.27290 ? 113 VAL A HA   1 
ATOM   1467 H  HB   . VAL A 1 90  ? -19.70100 11.13000  18.86400 1.000 21.52890 ? 113 VAL A HB   1 
ATOM   1468 H  HG11 . VAL A 1 90  ? -18.05100 12.75400  19.35500 1.000 23.38943 ? 113 VAL A HG11 1 
ATOM   1469 H  HG12 . VAL A 1 90  ? -19.26900 12.79400  20.37400 1.000 23.38943 ? 113 VAL A HG12 1 
ATOM   1470 H  HG13 . VAL A 1 90  ? -17.90000 12.10700  20.79800 1.000 23.38943 ? 113 VAL A HG13 1 
ATOM   1471 H  HG21 . VAL A 1 90  ? -17.55500 10.71600  18.07800 1.000 24.14474 ? 113 VAL A HG21 1 
ATOM   1472 H  HG22 . VAL A 1 90  ? -17.15300 10.05300  19.46500 1.000 24.14474 ? 113 VAL A HG22 1 
ATOM   1473 H  HG23 . VAL A 1 90  ? -18.20400 9.33400   18.51600 1.000 24.14474 ? 113 VAL A HG23 1 
ATOM   1474 N  N    . ASN A 1 91  ? -20.17300 11.24200  22.68000 1.000 16.96076 ? 114 ASN A N    1 
ATOM   1475 C  CA   . ASN A 1 91  ? -20.94400 11.95700  23.69200 1.000 17.78960 ? 114 ASN A CA   1 
ATOM   1476 C  C    . ASN A 1 91  ? -21.89400 11.06900  24.47700 1.000 18.16664 ? 114 ASN A C    1 
ATOM   1477 O  O    . ASN A 1 91  ? -22.66300 11.59400  25.30100 1.000 19.42838 ? 114 ASN A O    1 
ATOM   1478 C  CB   . ASN A 1 91  ? -21.66100 13.18000  23.11700 1.000 19.25106 ? 114 ASN A CB   1 
ATOM   1479 C  CG   . ASN A 1 91  ? -20.68400 14.19600  22.59900 1.000 21.75068 ? 114 ASN A CG   1 
ATOM   1480 O  OD1  . ASN A 1 91  ? -19.62100 14.38000  23.19300 1.000 22.46294 ? 114 ASN A OD1  1 
ATOM   1481 N  ND2  . ASN A 1 91  ? -21.00900 14.84000  21.48600 1.000 24.70732 ? 114 ASN A ND2  1 
ATOM   1482 H  H    . ASN A 1 91  ? -19.36600 11.09900  22.94000 1.000 20.35096 ? 114 ASN A H    1 
ATOM   1483 H  HA   . ASN A 1 91  ? -20.32300 12.28900  24.36000 1.000 21.34557 ? 114 ASN A HA   1 
ATOM   1484 H  HB2  . ASN A 1 91  ? -22.23100 12.90200  22.38300 1.000 23.09933 ? 114 ASN A HB2  1 
ATOM   1485 H  HB3  . ASN A 1 91  ? -22.19500 13.59600  23.81200 1.000 23.09933 ? 114 ASN A HB3  1 
ATOM   1486 H  HD21 . ASN A 1 91  ? -20.47500 15.42900  21.15800 1.000 29.64683 ? 114 ASN A HD21 1 
ATOM   1487 H  HD22 . ASN A 1 91  ? -21.75300 14.66700  21.09100 1.000 29.64683 ? 114 ASN A HD22 1 
ATOM   1488 N  N    . GLY A 1 92  ? -21.86200 9.75900   24.26100 1.000 17.39937 ? 115 GLY A N    1 
ATOM   1489 C  CA   . GLY A 1 92  ? -22.55300 8.82300   25.12100 1.000 17.11630 ? 115 GLY A CA   1 
ATOM   1490 C  C    . GLY A 1 92  ? -21.54400 7.88600   25.75000 1.000 16.06961 ? 115 GLY A C    1 
ATOM   1491 O  O    . GLY A 1 92  ? -20.33700 8.13600   25.67400 1.000 16.27093 ? 115 GLY A O    1 
ATOM   1492 H  H    . GLY A 1 92  ? -21.44000 9.38600   23.61100 1.000 20.87730 ? 115 GLY A H    1 
ATOM   1493 H  HA2  . GLY A 1 92  ? -23.02500 9.30100   25.82100 1.000 20.53761 ? 115 GLY A HA2  1 
ATOM   1494 H  HA3  . GLY A 1 92  ? -23.19100 8.30600   24.60600 1.000 20.53761 ? 115 GLY A HA3  1 
ATOM   1495 N  N    . THR A 1 93  ? -22.01600 6.81500   26.37500 1.000 15.09770 ? 116 THR A N    1 
ATOM   1496 C  CA   . THR A 1 93  ? -21.13400 5.79300   26.91200 1.000 14.10887 ? 116 THR A CA   1 
ATOM   1497 C  C    . THR A 1 93  ? -21.35700 4.47300   26.18200 1.000 14.25908 ? 116 THR A C    1 
ATOM   1498 O  O    . THR A 1 93  ? -22.41200 4.23100   25.58500 1.000 14.84217 ? 116 THR A O    1 
ATOM   1499 C  CB   . THR A 1 93  ? -21.32300 5.56200   28.42600 1.000 13.72280 ? 116 THR A CB   1 
ATOM   1500 O  OG1  . THR A 1 93  ? -22.63600 5.04300   28.66800 1.000 13.94705 ? 116 THR A OG1  1 
ATOM   1501 C  CG2  . THR A 1 93  ? -21.09200 6.84000   29.22800 1.000 15.58246 ? 116 THR A CG2  1 
ATOM   1502 H  H    . THR A 1 93  ? -22.85200 6.65800   26.50000 1.000 18.11529 ? 116 THR A H    1 
ATOM   1503 H  HA   . THR A 1 93  ? -20.22200 6.09100   26.77200 1.000 16.92870 ? 116 THR A HA   1 
ATOM   1504 H  HB   . THR A 1 93  ? -20.66400 4.92100   28.73600 1.000 16.46541 ? 116 THR A HB   1 
ATOM   1505 H  HG1  . THR A 1 93  ? -23.14600 5.66000   28.92400 1.000 16.73451 ? 116 THR A HG1  1 
ATOM   1506 H  HG21 . THR A 1 93  ? -21.35200 6.70300   30.15200 1.000 18.69700 ? 116 THR A HG21 1 
ATOM   1507 H  HG22 . THR A 1 93  ? -20.15400 7.08500   29.19800 1.000 18.69700 ? 116 THR A HG22 1 
ATOM   1508 H  HG23 . THR A 1 93  ? -21.61800 7.56400   28.85700 1.000 18.69700 ? 116 THR A HG23 1 
ATOM   1509 N  N    . MET A 1 94  ? -20.35200 3.61200   26.27200 1.000 13.48475 ? 117 MET A N    1 
ATOM   1510 C  CA   . MET A 1 94  ? -20.44400 2.21700   25.86700 1.000 13.92440 ? 117 MET A CA   1 
ATOM   1511 C  C    . MET A 1 94  ? -19.98700 1.37200   27.04800 1.000 13.88915 ? 117 MET A C    1 
ATOM   1512 O  O    . MET A 1 94  ? -19.11900 1.78300   27.82300 1.000 14.27257 ? 117 MET A O    1 
ATOM   1513 C  CB   . MET A 1 94  ? -19.53600 1.94000   24.67300 1.000 14.42279 ? 117 MET A CB   1 
ATOM   1514 C  CG   . MET A 1 94  ? -19.93600 2.65800   23.38900 1.000 15.12535 ? 117 MET A CG   1 
ATOM   1515 S  SD   . MET A 1 94  ? -18.72600 2.47400   22.05100 1.000 15.49073 ? 117 MET A SD   1 
ATOM   1516 C  CE   . MET A 1 94  ? -18.81800 0.71300   21.69200 1.000 16.30134 ? 117 MET A CE   1 
ATOM   1517 H  H    . MET A 1 94  ? -19.57500 3.82100   26.57700 1.000 16.17975 ? 117 MET A H    1 
ATOM   1518 H  HA   . MET A 1 94  ? -21.35200 1.98900   25.61500 1.000 16.70733 ? 117 MET A HA   1 
ATOM   1519 H  HB2  . MET A 1 94  ? -18.63500 2.22300   24.89700 1.000 17.30539 ? 117 MET A HB2  1 
ATOM   1520 H  HB3  . MET A 1 94  ? -19.54800 0.98700   24.49000 1.000 17.30539 ? 117 MET A HB3  1 
ATOM   1521 H  HG2  . MET A 1 94  ? -20.78000 2.29700   23.07700 1.000 18.14847 ? 117 MET A HG2  1 
ATOM   1522 H  HG3  . MET A 1 94  ? -20.02900 3.60500   23.57600 1.000 18.14847 ? 117 MET A HG3  1 
ATOM   1523 H  HE1  . MET A 1 94  ? -18.25500 0.51700   20.92600 1.000 19.55965 ? 117 MET A HE1  1 
ATOM   1524 H  HE2  . MET A 1 94  ? -18.50800 0.21600   22.46500 1.000 19.55965 ? 117 MET A HE2  1 
ATOM   1525 H  HE3  . MET A 1 94  ? -19.73800 0.47800   21.49500 1.000 19.55965 ? 117 MET A HE3  1 
ATOM   1526 N  N    . SER A 1 95  ? -20.56100 0.17900   27.17700 1.000 13.52097 ? 118 SER A N    1 
ATOM   1527 C  CA   . SER A 1 95  ? -20.09200 -0.73400  28.21200 1.000 13.32434 ? 118 SER A CA   1 
ATOM   1528 C  C    . SER A 1 95  ? -18.77400 -1.38500  27.79400 1.000 12.22106 ? 118 SER A C    1 
ATOM   1529 O  O    . SER A 1 95  ? -18.42000 -1.43800  26.61700 1.000 12.19905 ? 118 SER A O    1 
ATOM   1530 C  CB   . SER A 1 95  ? -21.12500 -1.82700  28.47000 1.000 13.86619 ? 118 SER A CB   1 
ATOM   1531 O  OG   . SER A 1 95  ? -21.20400 -2.69800  27.36000 1.000 14.04281 ? 118 SER A OG   1 
ATOM   1532 H  H    . SER A 1 95  ? -21.20600 -0.11600  26.69100 1.000 16.22321 ? 118 SER A H    1 
ATOM   1533 H  HA   . SER A 1 95  ? -19.95200 -0.23700  29.03300 1.000 15.98726 ? 118 SER A HA   1 
ATOM   1534 H  HB2  . SER A 1 95  ? -20.86200 -2.33400  29.25400 1.000 16.63748 ? 118 SER A HB2  1 
ATOM   1535 H  HB3  . SER A 1 95  ? -21.99200 -1.41700  28.61500 1.000 16.63748 ? 118 SER A HB3  1 
ATOM   1536 H  HG   . SER A 1 95  ? -21.77000 -3.30000  27.50700 1.000 16.84943 ? 118 SER A HG   1 
ATOM   1537 N  N    . LEU A 1 96  ? -18.04800 -1.90700  28.78300 1.000 12.33409 ? 119 LEU A N    1 
ATOM   1538 C  CA   . LEU A 1 96  ? -16.83600 -2.66100  28.47100 1.000 12.75524 ? 119 LEU A CA   1 
ATOM   1539 C  C    . LEU A 1 96  ? -17.13300 -3.88400  27.60500 1.000 11.99700 ? 119 LEU A C    1 
ATOM   1540 O  O    . LEU A 1 96  ? -16.32500 -4.23500  26.74400 1.000 11.79641 ? 119 LEU A O    1 
ATOM   1541 C  CB   . LEU A 1 96  ? -16.08700 -3.03500  29.75100 1.000 13.09272 ? 119 LEU A CB   1 
ATOM   1542 C  CG   . LEU A 1 96  ? -15.27900 -1.87900  30.35700 1.000 13.73005 ? 119 LEU A CG   1 
ATOM   1543 C  CD1  . LEU A 1 96  ? -14.74900 -2.22000  31.73900 1.000 15.46848 ? 119 LEU A CD1  1 
ATOM   1544 C  CD2  . LEU A 1 96  ? -14.12700 -1.47800  29.45200 1.000 14.72479 ? 119 LEU A CD2  1 
ATOM   1545 H  H    . LEU A 1 96  ? -18.23000 -1.84000  29.62100 1.000 14.79896 ? 119 LEU A H    1 
ATOM   1546 H  HA   . LEU A 1 96  ? -16.24000 -2.09300  27.95900 1.000 15.30434 ? 119 LEU A HA   1 
ATOM   1547 H  HB2  . LEU A 1 96  ? -16.73200 -3.32600  30.41500 1.000 15.70931 ? 119 LEU A HB2  1 
ATOM   1548 H  HB3  . LEU A 1 96  ? -15.46900 -3.75500  29.55000 1.000 15.70931 ? 119 LEU A HB3  1 
ATOM   1549 H  HG   . LEU A 1 96  ? -15.88200 -1.12400  30.44500 1.000 16.47411 ? 119 LEU A HG   1 
ATOM   1550 H  HD11 . LEU A 1 96  ? -14.32400 -1.43400  32.11700 1.000 18.56023 ? 119 LEU A HD11 1 
ATOM   1551 H  HD12 . LEU A 1 96  ? -15.48900 -2.49800  32.30200 1.000 18.56023 ? 119 LEU A HD12 1 
ATOM   1552 H  HD13 . LEU A 1 96  ? -14.10400 -2.94000  31.66200 1.000 18.56023 ? 119 LEU A HD13 1 
ATOM   1553 H  HD21 . LEU A 1 96  ? -13.60100 -0.79300  29.89500 1.000 17.66779 ? 119 LEU A HD21 1 
ATOM   1554 H  HD22 . LEU A 1 96  ? -13.57600 -2.25700  29.27700 1.000 17.66779 ? 119 LEU A HD22 1 
ATOM   1555 H  HD23 . LEU A 1 96  ? -14.48400 -1.13200  28.61900 1.000 17.66779 ? 119 LEU A HD23 1 
ATOM   1556 N  N    . ALA A 1 97  ? -18.28900 -4.53200  27.78700 1.000 12.46937 ? 120 ALA A N    1 
ATOM   1557 C  CA   . ALA A 1 97  ? -18.68100 -5.61400  26.88300 1.000 12.15581 ? 120 ALA A CA   1 
ATOM   1558 C  C    . ALA A 1 97  ? -18.82100 -5.10400  25.45500 1.000 11.98242 ? 120 ALA A C    1 
ATOM   1559 O  O    . ALA A 1 97  ? -18.32800 -5.72800  24.50800 1.000 12.44515 ? 120 ALA A O    1 
ATOM   1560 C  CB   . ALA A 1 97  ? -19.98900 -6.25900  27.34900 1.000 14.26187 ? 120 ALA A CB   1 
ATOM   1561 H  H    . ALA A 1 97  ? -18.85300 -4.36700  28.41500 1.000 14.96130 ? 120 ALA A H    1 
ATOM   1562 H  HA   . ALA A 1 97  ? -17.99100 -6.29600  26.90200 1.000 14.58502 ? 120 ALA A HA   1 
ATOM   1563 H  HB1  . ALA A 1 97  ? -20.21900 -6.98100  26.74300 1.000 17.11229 ? 120 ALA A HB1  1 
ATOM   1564 H  HB2  . ALA A 1 97  ? -19.86700 -6.60700  28.24700 1.000 17.11229 ? 120 ALA A HB2  1 
ATOM   1565 H  HB3  . ALA A 1 97  ? -20.69000 -5.58900  27.34600 1.000 17.11229 ? 120 ALA A HB3  1 
ATOM   1566 N  N    . GLU A 1 98  ? -19.50000 -3.96700  25.27600 1.000 12.16453 ? 121 GLU A N    1 
ATOM   1567 C  CA   . GLU A 1 98  ? -19.67700 -3.42200  23.93100 1.000 12.25913 ? 121 GLU A CA   1 
ATOM   1568 C  C    . GLU A 1 98  ? -18.34400 -3.02600  23.32100 1.000 11.48283 ? 121 GLU A C    1 
ATOM   1569 O  O    . GLU A 1 98  ? -18.13100 -3.19100  22.11300 1.000 12.29089 ? 121 GLU A O    1 
ATOM   1570 C  CB   . GLU A 1 98  ? -20.61900 -2.21700  23.97300 1.000 14.26996 ? 121 GLU A CB   1 
ATOM   1571 C  CG   . GLU A 1 98  ? -22.04800 -2.59500  24.25800 1.000 17.29114 ? 121 GLU A CG   1 
ATOM   1572 C  CD   . GLU A 1 98  ? -22.95900 -1.41200  24.52600 1.000 20.08032 ? 121 GLU A CD   1 
ATOM   1573 O  OE1  . GLU A 1 98  ? -22.48200 -0.34400  24.95400 1.000 18.37577 ? 121 GLU A OE1  1 
ATOM   1574 O  OE2  . GLU A 1 98  ? -24.18000 -1.56500  24.31600 1.000 24.30314 ? 121 GLU A OE2  1 
ATOM   1575 H  H    . GLU A 1 98  ? -19.86000 -3.50300  25.90400 1.000 14.59549 ? 121 GLU A H    1 
ATOM   1576 H  HA   . GLU A 1 98  ? -20.08000 -4.10200  23.36900 1.000 14.70900 ? 121 GLU A HA   1 
ATOM   1577 H  HB2  . GLU A 1 98  ? -20.32500 -1.61200  24.67100 1.000 17.12201 ? 121 GLU A HB2  1 
ATOM   1578 H  HB3  . GLU A 1 98  ? -20.59400 -1.76900  23.11300 1.000 17.12201 ? 121 GLU A HB3  1 
ATOM   1579 H  HG2  . GLU A 1 98  ? -22.40200 -3.07100  23.49100 1.000 20.74742 ? 121 GLU A HG2  1 
ATOM   1580 H  HG3  . GLU A 1 98  ? -22.06800 -3.16500  25.04200 1.000 20.74742 ? 121 GLU A HG3  1 
ATOM   1581 N  N    . LEU A 1 99  ? -17.45800 -2.45100  24.12400 1.000 10.79857 ? 122 LEU A N    1 
ATOM   1582 C  CA   . LEU A 1 99  ? -16.13900 -2.08500  23.62500 1.000 10.77664 ? 122 LEU A CA   1 
ATOM   1583 C  C    . LEU A 1 99  ? -15.32800 -3.31700  23.24800 1.000 10.20041 ? 122 LEU A C    1 
ATOM   1584 O  O    . LEU A 1 99  ? -14.63100 -3.31700  22.22800 1.000 10.42174 ? 122 LEU A O    1 
ATOM   1585 C  CB   . LEU A 1 99  ? -15.41000 -1.23100  24.66600 1.000 11.13224 ? 122 LEU A CB   1 
ATOM   1586 C  CG   . LEU A 1 99  ? -16.03000 0.16400   24.84200 1.000 12.17017 ? 122 LEU A CG   1 
ATOM   1587 C  CD1  . LEU A 1 99  ? -15.66900 0.76400   26.19100 1.000 13.22663 ? 122 LEU A CD1  1 
ATOM   1588 C  CD2  . LEU A 1 99  ? -15.59800 1.09200   23.70700 1.000 13.03607 ? 122 LEU A CD2  1 
ATOM   1589 H  H    . LEU A 1 99  ? -17.59300 -2.26200  24.95200 1.000 12.95633 ? 122 LEU A H    1 
ATOM   1590 H  HA   . LEU A 1 99  ? -16.23800 -1.55000  22.82200 1.000 12.93001 ? 122 LEU A HA   1 
ATOM   1591 H  HB2  . LEU A 1 99  ? -15.44400 -1.68400  25.52300 1.000 13.35674 ? 122 LEU A HB2  1 
ATOM   1592 H  HB3  . LEU A 1 99  ? -14.48800 -1.11600  24.38800 1.000 13.35674 ? 122 LEU A HB3  1 
ATOM   1593 H  HG   . LEU A 1 99  ? -16.99500 0.07600   24.81200 1.000 14.60226 ? 122 LEU A HG   1 
ATOM   1594 H  HD11 . LEU A 1 99  ? -16.11300 1.62100   26.28400 1.000 15.87001 ? 122 LEU A HD11 1 
ATOM   1595 H  HD12 . LEU A 1 99  ? -15.96200 0.16200   26.89200 1.000 15.87001 ? 122 LEU A HD12 1 
ATOM   1596 H  HD13 . LEU A 1 99  ? -14.70800 0.88200   26.23600 1.000 15.87001 ? 122 LEU A HD13 1 
ATOM   1597 H  HD21 . LEU A 1 99  ? -16.12700 1.90400   23.74500 1.000 15.64134 ? 122 LEU A HD21 1 
ATOM   1598 H  HD22 . LEU A 1 99  ? -14.65800 1.30400   23.81300 1.000 15.64134 ? 122 LEU A HD22 1 
ATOM   1599 H  HD23 . LEU A 1 99  ? -15.74200 0.64200   22.86000 1.000 15.64134 ? 122 LEU A HD23 1 
ATOM   1600 N  N    . SER A 1 100 ? -15.42800 -4.38400  24.03400 1.000 10.52859 ? 123 SER A N    1 
ATOM   1601 C  CA   . SER A 1 100 ? -14.73900 -5.62200  23.69100 1.000 9.96934  ? 123 SER A CA   1 
ATOM   1602 C  C    . SER A 1 100 ? -15.24600 -6.16400  22.36000 1.000 10.42597 ? 123 SER A C    1 
ATOM   1603 O  O    . SER A 1 100 ? -14.45600 -6.56000  21.49700 1.000 11.08869 ? 123 SER A O    1 
ATOM   1604 C  CB   . SER A 1 100 ? -14.93600 -6.66100  24.79400 1.000 11.27128 ? 123 SER A CB   1 
ATOM   1605 O  OG   . SER A 1 100 ? -14.34600 -6.23500  26.01400 1.000 12.20910 ? 123 SER A OG   1 
ATOM   1606 H  H    . SER A 1 100 ? -15.88200 -4.41700  24.76300 1.000 12.63236 ? 123 SER A H    1 
ATOM   1607 H  HA   . SER A 1 100 ? -13.78900 -5.44100  23.61500 1.000 11.96126 ? 123 SER A HA   1 
ATOM   1608 H  HB2  . SER A 1 100 ? -15.88600 -6.79400  24.93500 1.000 13.52359 ? 123 SER A HB2  1 
ATOM   1609 H  HB3  . SER A 1 100 ? -14.52200 -7.49400  24.51900 1.000 13.52359 ? 123 SER A HB3  1 
ATOM   1610 H  HG   . SER A 1 100 ? -14.70200 -5.51900  26.27100 1.000 14.64897 ? 123 SER A HG   1 
ATOM   1611 N  N    . ALA A 1 101 ? -16.56900 -6.21200  22.19500 1.000 11.23978 ? 124 ALA A N    1 
ATOM   1612 C  CA   . ALA A 1 101 ? -17.14800 -6.68800  20.94500 1.000 12.11766 ? 124 ALA A CA   1 
ATOM   1613 C  C    . ALA A 1 101 ? -16.72400 -5.81200  19.77300 1.000 11.55797 ? 124 ALA A C    1 
ATOM   1614 O  O    . ALA A 1 101 ? -16.40700 -6.31900  18.68800 1.000 12.19630 ? 124 ALA A O    1 
ATOM   1615 C  CB   . ALA A 1 101 ? -18.66500 -6.71600  21.06700 1.000 13.02062 ? 124 ALA A CB   1 
ATOM   1616 H  H    . ALA A 1 101 ? -17.14600 -5.97600  22.78700 1.000 13.48578 ? 124 ALA A H    1 
ATOM   1617 H  HA   . ALA A 1 101 ? -16.83600 -7.59000  20.77100 1.000 14.53924 ? 124 ALA A HA   1 
ATOM   1618 H  HB1  . ALA A 1 101 ? -19.04300 -7.04200  20.23500 1.000 15.62279 ? 124 ALA A HB1  1 
ATOM   1619 H  HB2  . ALA A 1 101 ? -18.91300 -7.30600  21.79600 1.000 15.62279 ? 124 ALA A HB2  1 
ATOM   1620 H  HB3  . ALA A 1 101 ? -18.98500 -5.81800  21.24500 1.000 15.62279 ? 124 ALA A HB3  1 
ATOM   1621 N  N    . ALA A 1 102 ? -16.72000 -4.49300  19.96600 1.000 11.19074 ? 125 ALA A N    1 
ATOM   1622 C  CA   . ALA A 1 102 ? -16.35600 -3.60000  18.86900 1.000 11.15642 ? 125 ALA A CA   1 
ATOM   1623 C  C    . ALA A 1 102 ? -14.89600 -3.77700  18.48100 1.000 10.70835 ? 125 ALA A C    1 
ATOM   1624 O  O    . ALA A 1 102 ? -14.55300 -3.77500  17.28700 1.000 11.32455 ? 125 ALA A O    1 
ATOM   1625 C  CB   . ALA A 1 102 ? -16.62700 -2.15700  19.28400 1.000 11.97726 ? 125 ALA A CB   1 
ATOM   1626 H  H    . ALA A 1 102 ? -16.92000 -4.09900  20.70400 1.000 13.42694 ? 125 ALA A H    1 
ATOM   1627 H  HA   . ALA A 1 102 ? -16.89900 -3.80700  18.09200 1.000 13.38576 ? 125 ALA A HA   1 
ATOM   1628 H  HB1  . ALA A 1 102 ? -16.31000 -1.56300  18.58500 1.000 14.37077 ? 125 ALA A HB1  1 
ATOM   1629 H  HB2  . ALA A 1 102 ? -17.58100 -2.03900  19.41100 1.000 14.37077 ? 125 ALA A HB2  1 
ATOM   1630 H  HB3  . ALA A 1 102 ? -16.15700 -1.97300  20.11200 1.000 14.37077 ? 125 ALA A HB3  1 
ATOM   1631 N  N    . ALA A 1 103 ? -14.01600 -3.92100  19.47500 1.000 9.99212  ? 126 ALA A N    1 
ATOM   1632 C  CA   . ALA A 1 103 ? -12.60600 -4.14400  19.19800 1.000 10.08002 ? 126 ALA A CA   1 
ATOM   1633 C  C    . ALA A 1 103 ? -12.40500 -5.44900  18.44500 1.000 10.10062 ? 126 ALA A C    1 
ATOM   1634 O  O    . ALA A 1 103 ? -11.63400 -5.50800  17.48000 1.000 10.80711 ? 126 ALA A O    1 
ATOM   1635 C  CB   . ALA A 1 103 ? -11.81500 -4.17400  20.50600 1.000 10.47579 ? 126 ALA A CB   1 
ATOM   1636 H  H    . ALA A 1 103 ? -14.21300 -3.89300  20.31200 1.000 11.98860 ? 126 ALA A H    1 
ATOM   1637 H  HA   . ALA A 1 103 ? -12.27300 -3.41400  18.65300 1.000 12.09408 ? 126 ALA A HA   1 
ATOM   1638 H  HB1  . ALA A 1 103 ? -10.87600 -4.31100  20.30400 1.000 12.56899 ? 126 ALA A HB1  1 
ATOM   1639 H  HB2  . ALA A 1 103 ? -11.93400 -3.32800  20.96600 1.000 12.56899 ? 126 ALA A HB2  1 
ATOM   1640 H  HB3  . ALA A 1 103 ? -12.14400 -4.90000  21.05800 1.000 12.56899 ? 126 ALA A HB3  1 
ATOM   1641 N  N    . LEU A 1 104 ? -13.07700 -6.51400  18.88200 1.000 10.27728 ? 127 LEU A N    1 
ATOM   1642 C  CA   . LEU A 1 104 ? -12.82700 -7.83000  18.31000 1.000 10.36632 ? 127 LEU A CA   1 
ATOM   1643 C  C    . LEU A 1 104 ? -13.55000 -8.06600  16.99700 1.000 10.46762 ? 127 LEU A C    1 
ATOM   1644 O  O    . LEU A 1 104 ? -13.02500 -8.78100  16.13600 1.000 11.93671 ? 127 LEU A O    1 
ATOM   1645 C  CB   . LEU A 1 104 ? -13.25800 -8.91000  19.30000 1.000 10.49183 ? 127 LEU A CB   1 
ATOM   1646 C  CG   . LEU A 1 104 ? -12.38100 -8.99000  20.54600 1.000 10.70981 ? 127 LEU A CG   1 
ATOM   1647 C  CD1  . LEU A 1 104 ? -12.97200 -9.99100  21.50900 1.000 12.07962 ? 127 LEU A CD1  1 
ATOM   1648 C  CD2  . LEU A 1 104 ? -10.93200 -9.34200  20.20100 1.000 12.55001 ? 127 LEU A CD2  1 
ATOM   1649 H  H    . LEU A 1 104 ? -13.67500 -6.49900  19.50000 1.000 12.33079 ? 127 LEU A H    1 
ATOM   1650 H  HA   . LEU A 1 104 ? -11.87500 -7.89700  18.14200 1.000 12.43764 ? 127 LEU A HA   1 
ATOM   1651 H  HB2  . LEU A 1 104 ? -14.16600 -8.72400  19.58800 1.000 12.58824 ? 127 LEU A HB2  1 
ATOM   1652 H  HB3  . LEU A 1 104 ? -13.22100 -9.77100  18.85500 1.000 12.58824 ? 127 LEU A HB3  1 
ATOM   1653 H  HG   . LEU A 1 104 ? -12.35400 -8.12000  20.97300 1.000 12.84983 ? 127 LEU A HG   1 
ATOM   1654 H  HD11 . LEU A 1 104 ? -12.40100 -10.05200 22.29000 1.000 14.49359 ? 127 LEU A HD11 1 
ATOM   1655 H  HD12 . LEU A 1 104 ? -13.85800 -9.69300  21.76900 1.000 14.49359 ? 127 LEU A HD12 1 
ATOM   1656 H  HD13 . LEU A 1 104 ? -13.02900 -10.85500 21.07100 1.000 14.49359 ? 127 LEU A HD13 1 
ATOM   1657 H  HD21 . LEU A 1 104 ? -10.45500 -9.55200  21.01900 1.000 15.05807 ? 127 LEU A HD21 1 
ATOM   1658 H  HD22 . LEU A 1 104 ? -10.92600 -10.10900 19.60800 1.000 15.05807 ? 127 LEU A HD22 1 
ATOM   1659 H  HD23 . LEU A 1 104 ? -10.51900 -8.58100  19.76300 1.000 15.05807 ? 127 LEU A HD23 1 
ATOM   1660 N  N    . GLN A 1 105 ? -14.73200 -7.49300  16.82200 1.000 11.44153 ? 128 GLN A N    1 
ATOM   1661 C  CA   . GLN A 1 105 ? -15.56400 -7.85100  15.68000 1.000 12.34301 ? 128 GLN A CA   1 
ATOM   1662 C  C    . GLN A 1 105 ? -15.52900 -6.82500  14.56200 1.000 12.34687 ? 128 GLN A C    1 
ATOM   1663 O  O    . GLN A 1 105 ? -15.83300 -7.17200  13.41200 1.000 13.38948 ? 128 GLN A O    1 
ATOM   1664 C  CB   . GLN A 1 105 ? -17.01600 -8.07500  16.12500 1.000 12.46936 ? 128 GLN A CB   1 
ATOM   1665 C  CG   . GLN A 1 105 ? -17.12700 -9.16900  17.15800 1.000 12.80953 ? 128 GLN A CG   1 
ATOM   1666 C  CD   . GLN A 1 105 ? -18.54200 -9.44400  17.60600 1.000 14.55917 ? 128 GLN A CD   1 
ATOM   1667 O  OE1  . GLN A 1 105 ? -19.38400 -8.54800  17.67200 1.000 16.86080 ? 128 GLN A OE1  1 
ATOM   1668 N  NE2  . GLN A 1 105 ? -18.80300 -10.69600 17.94700 1.000 14.07263 ? 128 GLN A NE2  1 
ATOM   1669 H  H    . GLN A 1 105 ? -15.07200 -6.90100  17.34500 1.000 13.72789 ? 128 GLN A H    1 
ATOM   1670 H  HA   . GLN A 1 105 ? -15.24100 -8.68800  15.31200 1.000 14.80967 ? 128 GLN A HA   1 
ATOM   1671 H  HB2  . GLN A 1 105 ? -17.36100 -7.25600  16.51200 1.000 14.96128 ? 128 GLN A HB2  1 
ATOM   1672 H  HB3  . GLN A 1 105 ? -17.54900 -8.32900  15.35500 1.000 14.96128 ? 128 GLN A HB3  1 
ATOM   1673 H  HG2  . GLN A 1 105 ? -16.77100 -9.99000  16.78300 1.000 15.36949 ? 128 GLN A HG2  1 
ATOM   1674 H  HG3  . GLN A 1 105 ? -16.61400 -8.91300  17.94000 1.000 15.36949 ? 128 GLN A HG3  1 
ATOM   1675 H  HE21 . GLN A 1 105 ? -18.18400 -11.29100 17.90400 1.000 16.88521 ? 128 GLN A HE21 1 
ATOM   1676 H  HE22 . GLN A 1 105 ? -19.59200 -10.91400 18.21100 1.000 16.88521 ? 128 GLN A HE22 1 
ATOM   1677 N  N    . TYR A 1 106 ? -15.16900 -5.58300  14.87700 1.000 12.19371 ? 129 TYR A N    1 
ATOM   1678 C  CA   . TYR A 1 106 ? -15.01600 -4.52200  13.89400 1.000 12.80948 ? 129 TYR A CA   1 
ATOM   1679 C  C    . TYR A 1 106 ? -13.61800 -3.92500  13.90000 1.000 12.53370 ? 129 TYR A C    1 
ATOM   1680 O  O    . TYR A 1 106 ? -13.33300 -3.03900  13.09600 1.000 14.00223 ? 129 TYR A O    1 
ATOM   1681 C  CB   . TYR A 1 106 ? -16.07000 -3.43200  14.12200 1.000 14.08015 ? 129 TYR A CB   1 
ATOM   1682 C  CG   . TYR A 1 106 ? -17.45500 -3.95000  13.83200 1.000 15.19709 ? 129 TYR A CG   1 
ATOM   1683 C  CD1  . TYR A 1 106 ? -17.97300 -3.90800  12.54700 1.000 17.13332 ? 129 TYR A CD1  1 
ATOM   1684 C  CD2  . TYR A 1 106 ? -18.23500 -4.51600  14.83100 1.000 15.69617 ? 129 TYR A CD2  1 
ATOM   1685 C  CE1  . TYR A 1 106 ? -19.23500 -4.40600  12.26100 1.000 18.47660 ? 129 TYR A CE1  1 
ATOM   1686 C  CE2  . TYR A 1 106 ? -19.49600 -5.01800  14.55300 1.000 17.66276 ? 129 TYR A CE2  1 
ATOM   1687 C  CZ   . TYR A 1 106 ? -19.98800 -4.95900  13.27200 1.000 19.12834 ? 129 TYR A CZ   1 
ATOM   1688 O  OH   . TYR A 1 106 ? -21.24000 -5.46200  12.99000 1.000 21.85821 ? 129 TYR A OH   1 
ATOM   1689 H  H    . TYR A 1 106 ? -15.00300 -5.32500  15.68000 1.000 14.63051 ? 129 TYR A H    1 
ATOM   1690 H  HA   . TYR A 1 106 ? -15.17300 -4.88000  13.00600 1.000 15.36943 ? 129 TYR A HA   1 
ATOM   1691 H  HB2  . TYR A 1 106 ? -16.03800 -3.14100  15.04700 1.000 16.89424 ? 129 TYR A HB2  1 
ATOM   1692 H  HB3  . TYR A 1 106 ? -15.89200 -2.68300  13.53200 1.000 16.89424 ? 129 TYR A HB3  1 
ATOM   1693 H  HD1  . TYR A 1 106 ? -17.46400 -3.53800  11.86300 1.000 20.55803 ? 129 TYR A HD1  1 
ATOM   1694 H  HD2  . TYR A 1 106 ? -17.90500 -4.55900  15.69900 1.000 18.83346 ? 129 TYR A HD2  1 
ATOM   1695 H  HE1  . TYR A 1 106 ? -19.57000 -4.36600  11.39500 1.000 22.16997 ? 129 TYR A HE1  1 
ATOM   1696 H  HE2  . TYR A 1 106 ? -20.00800 -5.39500  15.23300 1.000 21.19336 ? 129 TYR A HE2  1 
ATOM   1697 H  HH   . TYR A 1 106 ? -21.53100 -5.89500  13.64900 1.000 26.22790 ? 129 TYR A HH   1 
ATOM   1698 N  N    . SER A 1 107 ? -12.73500 -4.39100  14.77100 1.000 11.31353 ? 130 SER A N    1 
ATOM   1699 C  CA   . SER A 1 107 ? -11.38500 -3.85300  14.87900 1.000 11.00481 ? 130 SER A CA   1 
ATOM   1700 C  C    . SER A 1 107 ? -11.38800 -2.36700  15.23500 1.000 10.68804 ? 130 SER A C    1 
ATOM   1701 O  O    . SER A 1 107 ? -10.51100 -1.61900  14.82500 1.000 11.77060 ? 130 SER A O    1 
ATOM   1702 C  CB   . SER A 1 107 ? -10.51500 -4.14600  13.65500 1.000 11.23177 ? 130 SER A CB   1 
ATOM   1703 O  OG   . SER A 1 107 ? -9.18200  -4.38700  14.06100 1.000 10.88686 ? 130 SER A OG   1 
ATOM   1704 H  H    . SER A 1 107 ? -12.89600 -5.03200  15.32100 1.000 13.57428 ? 130 SER A H    1 
ATOM   1705 H  HA   . SER A 1 107 ? -10.95400 -4.31700  15.61400 1.000 13.20382 ? 130 SER A HA   1 
ATOM   1706 H  HB2  . SER A 1 107 ? -10.85800 -4.93100  13.20000 1.000 13.47618 ? 130 SER A HB2  1 
ATOM   1707 H  HB3  . SER A 1 107 ? -10.53500 -3.38200  13.05800 1.000 13.47618 ? 130 SER A HB3  1 
ATOM   1708 H  HG   . SER A 1 107 ? -8.80700  -3.66200  14.25900 1.000 13.06228 ? 130 SER A HG   1 
ATOM   1709 N  N    . ASP A 1 108 ? -12.35200 -1.93500  16.03900 1.000 10.71401 ? 131 ASP A N    1 
ATOM   1710 C  CA   . ASP A 1 108 ? -12.44700 -0.52800  16.40100 1.000 10.51936 ? 131 ASP A CA   1 
ATOM   1711 C  C    . ASP A 1 108 ? -11.27000 -0.12200  17.29300 1.000 10.45557 ? 131 ASP A C    1 
ATOM   1712 O  O    . ASP A 1 108 ? -10.98800 -0.77200  18.30700 1.000 11.62636 ? 131 ASP A O    1 
ATOM   1713 C  CB   . ASP A 1 108 ? -13.78500 -0.28000  17.09600 1.000 10.55058 ? 131 ASP A CB   1 
ATOM   1714 C  CG   . ASP A 1 108 ? -14.04400 1.18900   17.34300 1.000 11.14038 ? 131 ASP A CG   1 
ATOM   1715 O  OD1  . ASP A 1 108 ? -13.32500 1.79300   18.16800 1.000 11.55547 ? 131 ASP A OD1  1 
ATOM   1716 O  OD2  . ASP A 1 108 ? -14.94900 1.74800   16.68800 1.000 12.33848 ? 131 ASP A OD2  1 
ATOM   1717 H  H    . ASP A 1 108 ? -12.96000 -2.43400  16.38600 1.000 12.85486 ? 131 ASP A H    1 
ATOM   1718 H  HA   . ASP A 1 108 ? -12.40800 0.02900   15.60800 1.000 12.62128 ? 131 ASP A HA   1 
ATOM   1719 H  HB2  . ASP A 1 108 ? -14.50100 -0.62200  16.53800 1.000 12.65875 ? 131 ASP A HB2  1 
ATOM   1720 H  HB3  . ASP A 1 108 ? -13.78600 -0.73400  17.95300 1.000 12.65875 ? 131 ASP A HB3  1 
ATOM   1721 N  N    . ASN A 1 109 ? -10.58200 0.96700   16.92100 1.000 10.18790 ? 132 ASN A N    1 
ATOM   1722 C  CA   . ASN A 1 109 ? -9.38300  1.37300   17.64900 1.000 10.40612 ? 132 ASN A CA   1 
ATOM   1723 C  C    . ASN A 1 109 ? -9.67700  2.18800   18.90400 1.000 10.20941 ? 132 ASN A C    1 
ATOM   1724 O  O    . ASN A 1 109 ? -8.87200  2.14900   19.84700 1.000 10.17573 ? 132 ASN A O    1 
ATOM   1725 C  CB   . ASN A 1 109 ? -8.43800  2.14200   16.72300 1.000 11.29780 ? 132 ASN A CB   1 
ATOM   1726 C  CG   . ASN A 1 109 ? -7.59600  1.23100   15.85900 1.000 13.73295 ? 132 ASN A CG   1 
ATOM   1727 O  OD1  . ASN A 1 109 ? -7.42200  0.05500   16.15600 1.000 14.27829 ? 132 ASN A OD1  1 
ATOM   1728 N  ND2  . ASN A 1 109 ? -7.04000  1.78900   14.78900 1.000 16.73818 ? 132 ASN A ND2  1 
ATOM   1729 H  H    . ASN A 1 109 ? -10.78900 1.47800   16.26100 1.000 12.22354 ? 132 ASN A H    1 
ATOM   1730 H  HA   . ASN A 1 109 ? -8.93000  0.56700   17.94200 1.000 12.48540 ? 132 ASN A HA   1 
ATOM   1731 H  HB2  . ASN A 1 109 ? -8.96200  2.71100   16.13800 1.000 13.55541 ? 132 ASN A HB2  1 
ATOM   1732 H  HB3  . ASN A 1 109 ? -7.83900  2.68200   17.26200 1.000 13.55541 ? 132 ASN A HB3  1 
ATOM   1733 H  HD21 . ASN A 1 109 ? -6.55100  1.31600   14.26300 1.000 20.08387 ? 132 ASN A HD21 1 
ATOM   1734 H  HD22 . ASN A 1 109 ? -7.16800  2.62300   14.62300 1.000 20.08387 ? 132 ASN A HD22 1 
ATOM   1735 N  N    . VAL A 1 110 ? -10.77200 2.94700   18.93600 1.000 10.25681 ? 133 VAL A N    1 
ATOM   1736 C  CA   . VAL A 1 110 ? -11.16700 3.58800   20.19300 1.000 10.26036 ? 133 VAL A CA   1 
ATOM   1737 C  C    . VAL A 1 110 ? -11.45700 2.51800   21.22500 1.000 9.83292  ? 133 VAL A C    1 
ATOM   1738 O  O    . VAL A 1 110 ? -11.02500 2.58900   22.38000 1.000 10.14724 ? 133 VAL A O    1 
ATOM   1739 C  CB   . VAL A 1 110 ? -12.39300 4.49900   20.00200 1.000 11.07037 ? 133 VAL A CB   1 
ATOM   1740 C  CG1  . VAL A 1 110 ? -12.82100 5.05300   21.35500 1.000 11.47421 ? 133 VAL A CG1  1 
ATOM   1741 C  CG2  . VAL A 1 110 ? -12.08600 5.64300   19.05300 1.000 12.72484 ? 133 VAL A CG2  1 
ATOM   1742 H  H    . VAL A 1 110 ? -11.28800 3.10300   18.26700 1.000 12.30622 ? 133 VAL A H    1 
ATOM   1743 H  HA   . VAL A 1 110 ? -10.43300 4.14600   20.49400 1.000 12.31048 ? 133 VAL A HA   1 
ATOM   1744 H  HB   . VAL A 1 110 ? -13.11400 3.97800   19.61500 1.000 13.28250 ? 133 VAL A HB   1 
ATOM   1745 H  HG11 . VAL A 1 110 ? -13.40300 5.81600   21.21400 1.000 13.76710 ? 133 VAL A HG11 1 
ATOM   1746 H  HG12 . VAL A 1 110 ? -13.29400 4.36200   21.84400 1.000 13.76710 ? 133 VAL A HG12 1 
ATOM   1747 H  HG13 . VAL A 1 110 ? -12.03200 5.32600   21.84900 1.000 13.76710 ? 133 VAL A HG13 1 
ATOM   1748 H  HG21 . VAL A 1 110 ? -12.88800 6.17400   18.92800 1.000 15.26786 ? 133 VAL A HG21 1 
ATOM   1749 H  HG22 . VAL A 1 110 ? -11.38300 6.19100   19.43600 1.000 15.26786 ? 133 VAL A HG22 1 
ATOM   1750 H  HG23 . VAL A 1 110 ? -11.79500 5.27800   18.20200 1.000 15.26786 ? 133 VAL A HG23 1 
ATOM   1751 N  N    . ALA A 1 111 ? -12.20200 1.49800   20.80900 1.000 9.84084  ? 134 ALA A N    1 
ATOM   1752 C  CA   . ALA A 1 111 ? -12.53100 0.40600   21.71000 1.000 10.20390 ? 134 ALA A CA   1 
ATOM   1753 C  C    . ALA A 1 111 ? -11.27200 -0.23500  22.27500 1.000 9.74720  ? 134 ALA A C    1 
ATOM   1754 O  O    . ALA A 1 111 ? -11.17300 -0.46700  23.48300 1.000 10.04414 ? 134 ALA A O    1 
ATOM   1755 C  CB   . ALA A 1 111 ? -13.37800 -0.61800  20.96100 1.000 10.49656 ? 134 ALA A CB   1 
ATOM   1756 H  H    . ALA A 1 111 ? -12.52500 1.41700   20.01600 1.000 11.80706 ? 134 ALA A H    1 
ATOM   1757 H  HA   . ALA A 1 111 ? -13.04700 0.74400   22.45900 1.000 12.24273 ? 134 ALA A HA   1 
ATOM   1758 H  HB1  . ALA A 1 111 ? -13.61900 -1.33400  21.56900 1.000 12.59393 ? 134 ALA A HB1  1 
ATOM   1759 H  HB2  . ALA A 1 111 ? -14.17800 -0.18300  20.62800 1.000 12.59393 ? 134 ALA A HB2  1 
ATOM   1760 H  HB3  . ALA A 1 111 ? -12.86200 -0.97300  20.22100 1.000 12.59393 ? 134 ALA A HB3  1 
ATOM   1761 N  N    . MET A 1 112 ? -10.28600 -0.52300  21.42300 1.000 9.62089  ? 135 MET A N    1 
ATOM   1762 C  CA   . MET A 1 112 ? -9.01900  -1.05100  21.91900 1.000 9.93151  ? 135 MET A CA   1 
ATOM   1763 C  C    . MET A 1 112 ? -8.38500  -0.11700  22.94200 1.000 9.60855  ? 135 MET A C    1 
ATOM   1764 O  O    . MET A 1 112 ? -7.92100  -0.56400  23.99700 1.000 9.87591  ? 135 MET A O    1 
ATOM   1765 C  CB   . MET A 1 112 ? -8.07400  -1.29800  20.74500 1.000 10.33169 ? 135 MET A CB   1 
ATOM   1766 C  CG   . MET A 1 112 ? -6.65600  -1.67400  21.12400 1.000 9.96433  ? 135 MET A CG   1 
ATOM   1767 S  SD   . MET A 1 112 ? -6.53900  -3.17600  22.14700 1.000 9.91173  ? 135 MET A SD   1 
ATOM   1768 C  CE   . MET A 1 112 ? -4.94100  -3.78000  21.63500 1.000 10.92696 ? 135 MET A CE   1 
ATOM   1769 H  H    . MET A 1 112 ? -10.32600 -0.42400  20.57000 1.000 11.54311 ? 135 MET A H    1 
ATOM   1770 H  HA   . MET A 1 112 ? -9.18900  -1.90100  22.35400 1.000 11.91586 ? 135 MET A HA   1 
ATOM   1771 H  HB2  . MET A 1 112 ? -8.43300  -2.02300  20.21100 1.000 12.39608 ? 135 MET A HB2  1 
ATOM   1772 H  HB3  . MET A 1 112 ? -8.02700  -0.48700  20.21500 1.000 12.39608 ? 135 MET A HB3  1 
ATOM   1773 H  HG2  . MET A 1 112 ? -6.14800  -1.82900  20.31200 1.000 11.95525 ? 135 MET A HG2  1 
ATOM   1774 H  HG3  . MET A 1 112 ? -6.26400  -0.94300  21.62700 1.000 11.95525 ? 135 MET A HG3  1 
ATOM   1775 H  HE1  . MET A 1 112 ? -4.78500  -4.64600  22.04400 1.000 13.11040 ? 135 MET A HE1  1 
ATOM   1776 H  HE2  . MET A 1 112 ? -4.92900  -3.86400  20.66900 1.000 13.11040 ? 135 MET A HE2  1 
ATOM   1777 H  HE3  . MET A 1 112 ? -4.25900  -3.15200  21.92100 1.000 13.11040 ? 135 MET A HE3  1 
ATOM   1778 N  N    . ASN A 1 113 ? -8.33100  1.18200   22.64500 1.000 9.41211  ? 136 ASN A N    1 
ATOM   1779 C  CA   . ASN A 1 113 ? -7.73100  2.10700   23.60000 1.000 9.82422  ? 136 ASN A CA   1 
ATOM   1780 C  C    . ASN A 1 113 ? -8.45000  2.09100   24.94000 1.000 9.94407  ? 136 ASN A C    1 
ATOM   1781 O  O    . ASN A 1 113 ? -7.80900  2.24500   25.99500 1.000 10.07016 ? 136 ASN A O    1 
ATOM   1782 C  CB   . ASN A 1 113 ? -7.66600  3.51200   23.02800 1.000 9.83577  ? 136 ASN A CB   1 
ATOM   1783 C  CG   . ASN A 1 113 ? -6.45300  3.70700   22.15700 1.000 10.20321 ? 136 ASN A CG   1 
ATOM   1784 O  OD1  . ASN A 1 113 ? -5.53800  2.88800   22.16100 1.000 10.12091 ? 136 ASN A OD1  1 
ATOM   1785 N  ND2  . ASN A 1 113 ? -6.41900  4.80800   21.42500 1.000 10.51435 ? 136 ASN A ND2  1 
ATOM   1786 H  H    . ASN A 1 113 ? -8.62600  1.54000   21.92100 1.000 11.29258 ? 136 ASN A H    1 
ATOM   1787 H  HA   . ASN A 1 113 ? -6.81900  1.81900   23.75900 1.000 11.78711 ? 136 ASN A HA   1 
ATOM   1788 H  HB2  . ASN A 1 113 ? -8.45700  3.67400   22.48900 1.000 11.80097 ? 136 ASN A HB2  1 
ATOM   1789 H  HB3  . ASN A 1 113 ? -7.62400  4.15100   23.75600 1.000 11.80097 ? 136 ASN A HB3  1 
ATOM   1790 H  HD21 . ASN A 1 113 ? -5.74600  4.96200   20.91200 1.000 12.61527 ? 136 ASN A HD21 1 
ATOM   1791 H  HD22 . ASN A 1 113 ? -7.06900  5.36900   21.46200 1.000 12.61527 ? 136 ASN A HD22 1 
ATOM   1792 N  N    . LYS A 1 114 ? -9.77700  1.93500   24.93800 1.000 9.90667  ? 137 LYS A N    1 
ATOM   1793 C  CA   . LYS A 1 114 ? -10.50000 1.88300   26.20400 1.000 10.20128 ? 137 LYS A CA   1 
ATOM   1794 C  C    . LYS A 1 114 ? -10.19600 0.60000   26.96100 1.000 10.65448 ? 137 LYS A C    1 
ATOM   1795 O  O    . LYS A 1 114 ? -10.09400 0.61900   28.18900 1.000 11.10181 ? 137 LYS A O    1 
ATOM   1796 C  CB   . LYS A 1 114 ? -12.00000 2.03000   25.98000 1.000 10.32475 ? 137 LYS A CB   1 
ATOM   1797 C  CG   . LYS A 1 114 ? -12.43400 3.38200   25.41300 1.000 10.43540 ? 137 LYS A CG   1 
ATOM   1798 C  CD   . LYS A 1 114 ? -11.96100 4.56400   26.28600 1.000 10.64909 ? 137 LYS A CD   1 
ATOM   1799 C  CE   . LYS A 1 114 ? -12.50900 5.88400   25.81300 1.000 11.83632 ? 137 LYS A CE   1 
ATOM   1800 N  NZ   . LYS A 1 114 ? -11.99900 6.99700   26.65400 1.000 13.08140 ? 137 LYS A NZ   1 
ATOM   1801 H  H    . LYS A 1 114 ? -10.26600 1.85800   24.23500 1.000 11.88605 ? 137 LYS A H    1 
ATOM   1802 H  HA   . LYS A 1 114 ? -10.21300 2.63400   26.74700 1.000 12.23959 ? 137 LYS A HA   1 
ATOM   1803 H  HB2  . LYS A 1 114 ? -12.28600 1.34600   25.35500 1.000 12.38775 ? 137 LYS A HB2  1 
ATOM   1804 H  HB3  . LYS A 1 114 ? -12.45200 1.91100   26.83000 1.000 12.38775 ? 137 LYS A HB3  1 
ATOM   1805 H  HG2  . LYS A 1 114 ? -12.05500 3.49200   24.52700 1.000 12.52053 ? 137 LYS A HG2  1 
ATOM   1806 H  HG3  . LYS A 1 114 ? -13.40200 3.41100   25.36500 1.000 12.52053 ? 137 LYS A HG3  1 
ATOM   1807 H  HD2  . LYS A 1 114 ? -12.25900 4.42400   27.19900 1.000 12.77696 ? 137 LYS A HD2  1 
ATOM   1808 H  HD3  . LYS A 1 114 ? -10.99200 4.61300   26.25700 1.000 12.77696 ? 137 LYS A HD3  1 
ATOM   1809 H  HE2  . LYS A 1 114 ? -12.23400 6.03900   24.89600 1.000 14.20163 ? 137 LYS A HE2  1 
ATOM   1810 H  HE3  . LYS A 1 114 ? -13.47800 5.87200   25.87100 1.000 14.20163 ? 137 LYS A HE3  1 
ATOM   1811 H  HZ1  . LYS A 1 114 ? -12.52900 7.11300   27.36000 1.000 15.69572 ? 137 LYS A HZ1  1 
ATOM   1812 H  HZ2  . LYS A 1 114 ? -11.17600 6.81200   26.93800 1.000 15.69572 ? 137 LYS A HZ2  1 
ATOM   1813 H  HZ3  . LYS A 1 114 ? -11.97800 7.75100   26.18200 1.000 15.69572 ? 137 LYS A HZ3  1 
ATOM   1814 N  N    . LEU A 1 115 ? -10.05300 -0.52400  26.25800 1.000 10.11710 ? 138 LEU A N    1 
ATOM   1815 C  CA   . LEU A 1 115 ? -9.65400  -1.75700  26.93500 1.000 10.63228 ? 138 LEU A CA   1 
ATOM   1816 C  C    . LEU A 1 115 ? -8.26500  -1.61500  27.54700 1.000 10.04583 ? 138 LEU A C    1 
ATOM   1817 O  O    . LEU A 1 115 ? -8.03300  -1.98800  28.71100 1.000 11.40132 ? 138 LEU A O    1 
ATOM   1818 C  CB   . LEU A 1 115 ? -9.68100  -2.93300  25.95700 1.000 11.22697 ? 138 LEU A CB   1 
ATOM   1819 C  CG   . LEU A 1 115 ? -10.98400 -3.22800  25.23800 1.000 12.18169 ? 138 LEU A CG   1 
ATOM   1820 C  CD1  . LEU A 1 115 ? -10.77800 -4.38200  24.28400 1.000 12.76373 ? 138 LEU A CD1  1 
ATOM   1821 C  CD2  . LEU A 1 115 ? -12.12600 -3.52900  26.19400 1.000 14.23455 ? 138 LEU A CD2  1 
ATOM   1822 H  H    . LEU A 1 115 ? -10.17800 -0.59800  25.41000 1.000 12.13857 ? 138 LEU A H    1 
ATOM   1823 H  HA   . LEU A 1 115 ? -10.28900 -1.93900  27.64500 1.000 12.75679 ? 138 LEU A HA   1 
ATOM   1824 H  HB2  . LEU A 1 115 ? -9.01600  -2.76300  25.27200 1.000 13.47041 ? 138 LEU A HB2  1 
ATOM   1825 H  HB3  . LEU A 1 115 ? -9.44900  -3.73400  26.45300 1.000 13.47041 ? 138 LEU A HB3  1 
ATOM   1826 H  HG   . LEU A 1 115 ? -11.24600 -2.43600  24.74300 1.000 14.61608 ? 138 LEU A HG   1 
ATOM   1827 H  HD11 . LEU A 1 115 ? -11.60500 -4.54700  23.80500 1.000 15.31453 ? 138 LEU A HD11 1 
ATOM   1828 H  HD12 . LEU A 1 115 ? -10.07300 -4.15200  23.65800 1.000 15.31453 ? 138 LEU A HD12 1 
ATOM   1829 H  HD13 . LEU A 1 115 ? -10.52600 -5.16900  24.79100 1.000 15.31453 ? 138 LEU A HD13 1 
ATOM   1830 H  HD21 . LEU A 1 115 ? -12.92800 -3.71200  25.68000 1.000 17.07951 ? 138 LEU A HD21 1 
ATOM   1831 H  HD22 . LEU A 1 115 ? -11.89300 -4.30200  26.73100 1.000 17.07951 ? 138 LEU A HD22 1 
ATOM   1832 H  HD23 . LEU A 1 115 ? -12.26900 -2.75900  26.76700 1.000 17.07951 ? 138 LEU A HD23 1 
ATOM   1833 N  N    . ILE A 1 116 ? -7.32100  -1.08400  26.76700 1.000 10.30983 ? 139 ILE A N    1 
ATOM   1834 C  CA   . ILE A 1 116 ? -5.96500  -0.84600  27.25500 1.000 10.59587 ? 139 ILE A CA   1 
ATOM   1835 C  C    . ILE A 1 116 ? -5.99900  0.02900   28.50300 1.000 10.97827 ? 139 ILE A C    1 
ATOM   1836 O  O    . ILE A 1 116 ? -5.39400  -0.28600  29.53600 1.000 11.53902 ? 139 ILE A O    1 
ATOM   1837 C  CB   . ILE A 1 116 ? -5.11100  -0.20000  26.14700 1.000 10.21755 ? 139 ILE A CB   1 
ATOM   1838 C  CG1  . ILE A 1 116 ? -4.83600  -1.18400  25.00100 1.000 10.27004 ? 139 ILE A CG1  1 
ATOM   1839 C  CG2  . ILE A 1 116 ? -3.81500  0.31900   26.73900 1.000 11.36734 ? 139 ILE A CG2  1 
ATOM   1840 C  CD1  . ILE A 1 116 ? -4.18100  -0.53000  23.80300 1.000 10.56651 ? 139 ILE A CD1  1 
ATOM   1841 H  H    . ILE A 1 116 ? -7.44200  -0.85200  25.94800 1.000 12.36984 ? 139 ILE A H    1 
ATOM   1842 H  HA   . ILE A 1 116 ? -5.56700  -1.69800  27.49400 1.000 12.71309 ? 139 ILE A HA   1 
ATOM   1843 H  HB   . ILE A 1 116 ? -5.61000  0.54300   25.77300 1.000 12.25911 ? 139 ILE A HB   1 
ATOM   1844 H  HG12 . ILE A 1 116 ? -4.24400  -1.88300  25.32100 1.000 12.32210 ? 139 ILE A HG12 1 
ATOM   1845 H  HG13 . ILE A 1 116 ? -5.67600  -1.57000  24.70900 1.000 12.32210 ? 139 ILE A HG13 1 
ATOM   1846 H  HG21 . ILE A 1 116 ? -3.21700  0.57100   26.01700 1.000 13.63886 ? 139 ILE A HG21 1 
ATOM   1847 H  HG22 . ILE A 1 116 ? -4.00800  1.09200   27.29300 1.000 13.63886 ? 139 ILE A HG22 1 
ATOM   1848 H  HG23 . ILE A 1 116 ? -3.41100  -0.38000  27.27500 1.000 13.63886 ? 139 ILE A HG23 1 
ATOM   1849 H  HD11 . ILE A 1 116 ? -4.24100  -1.13100  23.04300 1.000 12.67786 ? 139 ILE A HD11 1 
ATOM   1850 H  HD12 . ILE A 1 116 ? -4.64300  0.30000   23.60500 1.000 12.67786 ? 139 ILE A HD12 1 
ATOM   1851 H  HD13 . ILE A 1 116 ? -3.25100  -0.35000  24.01000 1.000 12.67786 ? 139 ILE A HD13 1 
ATOM   1852 N  N    . ALA A 1 117 ? -6.69100  1.15900   28.41900 1.000 11.34712 ? 140 ALA A N    1 
ATOM   1853 C  CA   . ALA A 1 117 ? -6.68800  2.09300   29.53700 1.000 11.34224 ? 140 ALA A CA   1 
ATOM   1854 C  C    . ALA A 1 117 ? -7.30000  1.45100   30.76800 1.000 11.40747 ? 140 ALA A C    1 
ATOM   1855 O  O    . ALA A 1 117 ? -6.82700  1.64800   31.89600 1.000 12.97905 ? 140 ALA A O    1 
ATOM   1856 C  CB   . ALA A 1 117 ? -7.45600  3.36000   29.17200 1.000 13.15842 ? 140 ALA A CB   1 
ATOM   1857 H  H    . ALA A 1 117 ? -7.15900  1.40500   27.74100 1.000 13.61459 ? 140 ALA A H    1 
ATOM   1858 H  HA   . ALA A 1 117 ? -5.77200  2.34400   29.73500 1.000 13.60874 ? 140 ALA A HA   1 
ATOM   1859 H  HB1  . ALA A 1 117 ? -7.42900  3.97400   29.92300 1.000 15.78815 ? 140 ALA A HB1  1 
ATOM   1860 H  HB2  . ALA A 1 117 ? -7.04000  3.76900   28.39600 1.000 15.78815 ? 140 ALA A HB2  1 
ATOM   1861 H  HB3  . ALA A 1 117 ? -8.37500  3.12600   28.97000 1.000 15.78815 ? 140 ALA A HB3  1 
ATOM   1862 N  N    . HIS A 1 118 ? -8.36900  0.68500   30.58200 1.000 11.86322 ? 141 HIS A N    1 
ATOM   1863 C  CA   . HIS A 1 118 ? -9.07700  0.15200   31.72500 1.000 13.24836 ? 141 HIS A CA   1 
ATOM   1864 C  C    . HIS A 1 118 ? -8.16900  -0.73400  32.55600 1.000 14.84502 ? 141 HIS A C    1 
ATOM   1865 O  O    . HIS A 1 118 ? -8.16400  -0.64100  33.79400 1.000 16.18178 ? 141 HIS A O    1 
ATOM   1866 C  CB   . HIS A 1 118 ? -10.30800 -0.60600  31.27700 1.000 15.05198 ? 141 HIS A CB   1 
ATOM   1867 C  CG   . HIS A 1 118 ? -11.03100 -1.18200  32.42600 1.000 17.25929 ? 141 HIS A CG   1 
ATOM   1868 N  ND1  . HIS A 1 118 ? -11.85000 -0.41600  33.22100 1.000 17.85221 ? 141 HIS A ND1  1 
ATOM   1869 C  CD2  . HIS A 1 118 ? -10.96500 -2.39900  33.00500 1.000 18.72537 ? 141 HIS A CD2  1 
ATOM   1870 C  CE1  . HIS A 1 118 ? -12.29900 -1.15300  34.22100 1.000 18.79719 ? 141 HIS A CE1  1 
ATOM   1871 N  NE2  . HIS A 1 118 ? -11.78400 -2.36600  34.10600 1.000 20.12545 ? 141 HIS A NE2  1 
ATOM   1872 H  H    . HIS A 1 118 ? -8.69500  0.46600   29.81700 1.000 14.23392 ? 141 HIS A H    1 
ATOM   1873 H  HA   . HIS A 1 118 ? -9.37500  0.88700   32.28200 1.000 15.89608 ? 141 HIS A HA   1 
ATOM   1874 H  HB2  . HIS A 1 118 ? -10.90600 -0.00100  30.81100 1.000 18.06043 ? 141 HIS A HB2  1 
ATOM   1875 H  HB3  . HIS A 1 118 ? -10.04300 -1.33000  30.68800 1.000 18.06043 ? 141 HIS A HB3  1 
ATOM   1876 H  HD1  . HIS A 1 118 ? -12.04000 0.41200   33.08900 0.651 21.42071 ? 141 HIS A HD1  1 
ATOM   1877 H  HD2  . HIS A 1 118 ? -10.46000 -3.12400  32.71400 1.000 22.46850 ? 141 HIS A HD2  1 
ATOM   1878 H  HE1  . HIS A 1 118 ? -12.87800 -0.86800  34.89000 1.000 22.55468 ? 141 HIS A HE1  1 
ATOM   1879 N  N    . VAL A 1 119 ? -7.37000  -1.58300  31.89700 1.000 13.35372 ? 142 VAL A N    1 
ATOM   1880 C  CA   . VAL A 1 119 ? -6.54300  -2.52300  32.64700 1.000 14.53135 ? 142 VAL A CA   1 
ATOM   1881 C  C    . VAL A 1 119 ? -5.22500  -1.93700  33.10200 1.000 13.86988 ? 142 VAL A C    1 
ATOM   1882 O  O    . VAL A 1 119 ? -4.48900  -2.60800  33.83000 1.000 15.24816 ? 142 VAL A O    1 
ATOM   1883 C  CB   . VAL A 1 119 ? -6.29200  -3.82600  31.87900 1.000 14.41686 ? 142 VAL A CB   1 
ATOM   1884 C  CG1  . VAL A 1 119 ? -7.59800  -4.48800  31.58200 1.000 15.21889 ? 142 VAL A CG1  1 
ATOM   1885 C  CG2  . VAL A 1 119 ? -5.49700  -3.58500  30.61600 1.000 13.62995 ? 142 VAL A CG2  1 
ATOM   1886 H  H    A VAL A 1 119 ? -7.29500  -1.63000  31.04100 0.620 16.02252 ? 142 VAL A H    1 
ATOM   1887 H  H    B VAL A 1 119 ? -7.29500  -1.63000  31.04100 0.380 16.02252 ? 142 VAL A H    1 
ATOM   1888 H  HA   . VAL A 1 119 ? -7.04600  -2.75500  33.44300 1.000 17.43567 ? 142 VAL A HA   1 
ATOM   1889 H  HB   . VAL A 1 119 ? -5.75800  -4.42100  32.42900 1.000 17.29828 ? 142 VAL A HB   1 
ATOM   1890 H  HG11 . VAL A 1 119 ? -7.43200  -5.31500  31.10300 1.000 18.26072 ? 142 VAL A HG11 1 
ATOM   1891 H  HG12 . VAL A 1 119 ? -8.05400  -4.67500  32.41700 1.000 18.26072 ? 142 VAL A HG12 1 
ATOM   1892 H  HG13 . VAL A 1 119 ? -8.13700  -3.89300  31.03700 1.000 18.26072 ? 142 VAL A HG13 1 
ATOM   1893 H  HG21 . VAL A 1 119 ? -5.38400  -4.42800  30.14800 1.000 16.35399 ? 142 VAL A HG21 1 
ATOM   1894 H  HG22 . VAL A 1 119 ? -5.97900  -2.95800  30.05400 1.000 16.35399 ? 142 VAL A HG22 1 
ATOM   1895 H  HG23 . VAL A 1 119 ? -4.63100  -3.22000  30.85300 1.000 16.35399 ? 142 VAL A HG23 1 
ATOM   1896 N  N    . GLY A 1 120 ? -4.90400  -0.71600  32.69700 1.000 13.30503 ? 143 GLY A N    1 
ATOM   1897 C  CA   . GLY A 1 120 ? -3.73800  -0.02500  33.20800 1.000 13.75521 ? 143 GLY A CA   1 
ATOM   1898 C  C    . GLY A 1 120 ? -2.71200  0.35500   32.16800 1.000 13.37271 ? 143 GLY A C    1 
ATOM   1899 O  O    . GLY A 1 120 ? -1.68600  0.95100   32.52400 1.000 15.78250 ? 143 GLY A O    1 
ATOM   1900 H  H    . GLY A 1 120 ? -5.35400  -0.26400  32.12000 1.000 15.96409 ? 143 GLY A H    1 
ATOM   1901 H  HA2  . GLY A 1 120 ? -4.02800  0.79000   33.64700 1.000 16.50430 ? 143 GLY A HA2  1 
ATOM   1902 H  HA3  . GLY A 1 120 ? -3.30000  -0.59600  33.85900 1.000 16.50430 ? 143 GLY A HA3  1 
ATOM   1903 N  N    . GLY A 1 121 ? -2.93400  0.05300   30.89200 1.000 11.18694 ? 144 GLY A N    1 
ATOM   1904 C  CA   . GLY A 1 121 ? -2.04400  0.46600   29.84200 1.000 10.90721 ? 144 GLY A CA   1 
ATOM   1905 C  C    . GLY A 1 121 ? -1.34900  -0.69900  29.18700 1.000 10.07529 ? 144 GLY A C    1 
ATOM   1906 O  O    . GLY A 1 121 ? -1.52800  -1.86500  29.57700 1.000 10.41911 ? 144 GLY A O    1 
ATOM   1907 H  H    . GLY A 1 121 ? -3.61000  -0.40100  30.61500 1.000 13.42238 ? 144 GLY A H    1 
ATOM   1908 H  HA2  . GLY A 1 121 ? -2.54800  0.94200   29.16300 1.000 13.08670 ? 144 GLY A HA2  1 
ATOM   1909 H  HA3  . GLY A 1 121 ? -1.36900  1.05900   30.20800 1.000 13.08670 ? 144 GLY A HA3  1 
ATOM   1910 N  N    . PRO A 1 122 ? -0.53400  -0.40100  28.17000 1.000 9.75694  ? 145 PRO A N    1 
ATOM   1911 C  CA   . PRO A 1 122 ? 0.14200   -1.48800  27.43700 1.000 10.02433 ? 145 PRO A CA   1 
ATOM   1912 C  C    . PRO A 1 122 ? 0.97700   -2.39500  28.31400 1.000 10.14352 ? 145 PRO A C    1 
ATOM   1913 O  O    . PRO A 1 122 ? 1.02300   -3.61000  28.07900 1.000 10.41940 ? 145 PRO A O    1 
ATOM   1914 C  CB   . PRO A 1 122 ? 0.96900   -0.74300  26.38300 1.000 10.39353 ? 145 PRO A CB   1 
ATOM   1915 C  CG   . PRO A 1 122 ? 0.20500   0.55200   26.17900 1.000 10.56662 ? 145 PRO A CG   1 
ATOM   1916 C  CD   . PRO A 1 122 ? -0.28700  0.91500   27.55800 1.000 10.22745 ? 145 PRO A CD   1 
ATOM   1917 H  HA   . PRO A 1 122 ? -0.51900  -2.03400  26.98100 1.000 12.02725 ? 145 PRO A HA   1 
ATOM   1918 H  HB2  . PRO A 1 122 ? 1.86400   -0.57500  26.71600 1.000 12.47029 ? 145 PRO A HB2  1 
ATOM   1919 H  HB3  . PRO A 1 122 ? 1.01100   -1.25900  25.56300 1.000 12.47029 ? 145 PRO A HB3  1 
ATOM   1920 H  HG2  . PRO A 1 122 ? 0.79700   1.23600   25.82800 1.000 12.67800 ? 145 PRO A HG2  1 
ATOM   1921 H  HG3  . PRO A 1 122 ? -0.53600  0.41000   25.57000 1.000 12.67800 ? 145 PRO A HG3  1 
ATOM   1922 H  HD2  . PRO A 1 122 ? 0.38900   1.40600   28.05000 1.000 12.27100 ? 145 PRO A HD2  1 
ATOM   1923 H  HD3  . PRO A 1 122 ? -1.10500  1.43500   27.50900 1.000 12.27100 ? 145 PRO A HD3  1 
ATOM   1924 N  N    . ALA A 1 123 ? 1.63200   -1.85000  29.34300 1.000 10.22101 ? 146 ALA A N    1 
ATOM   1925 C  CA   . ALA A 1 123 ? 2.46300   -2.69200  30.19800 1.000 10.27257 ? 146 ALA A CA   1 
ATOM   1926 C  C    . ALA A 1 123 ? 1.61600   -3.64900  31.02100 1.000 10.23644 ? 146 ALA A C    1 
ATOM   1927 O  O    . ALA A 1 123 ? 2.10000   -4.71400  31.42300 1.000 10.25886 ? 146 ALA A O    1 
ATOM   1928 C  CB   . ALA A 1 123 ? 3.36300   -1.83500  31.09200 1.000 10.99245 ? 146 ALA A CB   1 
ATOM   1929 H  H    . ALA A 1 123 ? 1.61000   -1.01800  29.56000 1.000 12.26327 ? 146 ALA A H    1 
ATOM   1930 H  HA   . ALA A 1 123 ? 3.05200   -3.22300  29.63900 1.000 12.32514 ? 146 ALA A HA   1 
ATOM   1931 H  HB1  . ALA A 1 123 ? 3.93000   -2.41700  31.62100 1.000 13.18900 ? 146 ALA A HB1  1 
ATOM   1932 H  HB2  . ALA A 1 123 ? 3.90900   -1.26000  30.53300 1.000 13.18900 ? 146 ALA A HB2  1 
ATOM   1933 H  HB3  . ALA A 1 123 ? 2.80700   -1.29600  31.67600 1.000 13.18900 ? 146 ALA A HB3  1 
ATOM   1934 N  N    . SER A 1 124 ? 0.37500   -3.26200  31.31900 1.000 9.81732  ? 147 SER A N    1 
ATOM   1935 C  CA   A SER A 1 124 ? -0.51800  -4.15800  32.03900 0.816 10.58692 ? 147 SER A CA   1 
ATOM   1936 C  CA   B SER A 1 124 ? -0.53200  -4.15200  32.03800 0.184 10.26360 ? 147 SER A CA   1 
ATOM   1937 C  C    . SER A 1 124 ? -1.03500  -5.27600  31.13900 1.000 10.33277 ? 147 SER A C    1 
ATOM   1938 O  O    . SER A 1 124 ? -1.15300  -6.42500  31.58100 1.000 10.57666 ? 147 SER A O    1 
ATOM   1939 C  CB   A SER A 1 124 ? -1.67600  -3.37300  32.64500 0.816 11.57203 ? 147 SER A CB   1 
ATOM   1940 C  CB   B SER A 1 124 ? -1.70600  -3.35200  32.59700 0.184 10.36071 ? 147 SER A CB   1 
ATOM   1941 O  OG   A SER A 1 124 ? -2.54000  -4.25200  33.33400 0.816 13.18286 ? 147 SER A OG   1 
ATOM   1942 O  OG   B SER A 1 124 ? -1.24400  -2.30400  33.42400 0.184 10.58416 ? 147 SER A OG   1 
ATOM   1943 H  H    A SER A 1 124 ? 0.03300   -2.49900  31.11900 0.816 11.77884 ? 147 SER A H    1 
ATOM   1944 H  H    B SER A 1 124 ? 0.03700   -2.49700  31.11900 0.184 11.77884 ? 147 SER A H    1 
ATOM   1945 H  HA   A SER A 1 124 ? -0.02300  -4.56900  32.76600 0.816 12.70235 ? 147 SER A HA   1 
ATOM   1946 H  HA   B SER A 1 124 ? -0.05400  -4.55300  32.78000 0.184 12.31437 ? 147 SER A HA   1 
ATOM   1947 H  HB2  A SER A 1 124 ? -1.32600  -2.71500  33.26600 0.816 13.88449 ? 147 SER A HB2  1 
ATOM   1948 H  HB2  B SER A 1 124 ? -2.21200  -2.97400  31.86000 0.184 12.43090 ? 147 SER A HB2  1 
ATOM   1949 H  HB3  A SER A 1 124 ? -2.16800  -2.93100  31.93600 0.816 13.88449 ? 147 SER A HB3  1 
ATOM   1950 H  HB3  B SER A 1 124 ? -2.27100  -3.94200  33.11900 0.184 12.43090 ? 147 SER A HB3  1 
ATOM   1951 H  HG   A SER A 1 124 ? -3.19300  -3.82600  33.64700 0.816 15.81749 ? 147 SER A HG   1 
ATOM   1952 H  HG   B SER A 1 124 ? -1.85400  -2.06200  33.94900 0.184 12.69904 ? 147 SER A HG   1 
ATOM   1953 N  N    . VAL A 1 125 ? -1.34300  -4.97000  29.87300 1.000 10.13493 ? 148 VAL A N    1 
ATOM   1954 C  CA   . VAL A 1 125 ? -1.71300  -6.03400  28.94800 1.000 9.75318  ? 148 VAL A CA   1 
ATOM   1955 C  C    . VAL A 1 125 ? -0.55400  -7.01900  28.81800 1.000 9.16290  ? 148 VAL A C    1 
ATOM   1956 O  O    . VAL A 1 125 ? -0.74000  -8.24100  28.81600 1.000 9.88463  ? 148 VAL A O    1 
ATOM   1957 C  CB   . VAL A 1 125 ? -2.13300  -5.46100  27.57100 1.000 9.87536  ? 148 VAL A CB   1 
ATOM   1958 C  CG1  . VAL A 1 125 ? -2.52000  -6.60700  26.62800 1.000 10.34397 ? 148 VAL A CG1  1 
ATOM   1959 C  CG2  . VAL A 1 125 ? -3.29300  -4.48900  27.70000 1.000 10.65243 ? 148 VAL A CG2  1 
ATOM   1960 H  H    . VAL A 1 125 ? -1.34300  -4.17700  29.54000 1.000 12.15997 ? 148 VAL A H    1 
ATOM   1961 H  HA   . VAL A 1 125 ? -2.48400  -6.50000  29.30600 1.000 11.70187 ? 148 VAL A HA   1 
ATOM   1962 H  HB   . VAL A 1 125 ? -1.38000  -4.97500  27.20100 1.000 11.84848 ? 148 VAL A HB   1 
ATOM   1963 H  HG11 . VAL A 1 125 ? -2.85700  -6.23300  25.79900 1.000 12.41081 ? 148 VAL A HG11 1 
ATOM   1964 H  HG12 . VAL A 1 125 ? -1.73500  -7.14900  26.45200 1.000 12.41081 ? 148 VAL A HG12 1 
ATOM   1965 H  HG13 . VAL A 1 125 ? -3.20600  -7.14600  27.05100 1.000 12.41081 ? 148 VAL A HG13 1 
ATOM   1966 H  HG21 . VAL A 1 125 ? -3.48300  -4.10700  26.82900 1.000 12.78096 ? 148 VAL A HG21 1 
ATOM   1967 H  HG22 . VAL A 1 125 ? -4.07000  -4.96700  28.02900 1.000 12.78096 ? 148 VAL A HG22 1 
ATOM   1968 H  HG23 . VAL A 1 125 ? -3.04800  -3.78700  28.32300 1.000 12.78096 ? 148 VAL A HG23 1 
ATOM   1969 N  N    . THR A 1 126 ? 0.66800   -6.48900  28.73000 1.000 9.05074  ? 149 THR A N    1 
ATOM   1970 C  CA   . THR A 1 126 ? 1.85100   -7.32800  28.63400 1.000 9.40806  ? 149 THR A CA   1 
ATOM   1971 C  C    . THR A 1 126 ? 2.02700   -8.17400  29.89300 1.000 9.44833  ? 149 THR A C    1 
ATOM   1972 O  O    . THR A 1 126 ? 2.33200   -9.36700  29.80700 1.000 10.06496 ? 149 THR A O    1 
ATOM   1973 C  CB   . THR A 1 126 ? 3.07900   -6.45700  28.34400 1.000 10.25029 ? 149 THR A CB   1 
ATOM   1974 O  OG1  . THR A 1 126 ? 2.88100   -5.77200  27.09500 1.000 10.29209 ? 149 THR A OG1  1 
ATOM   1975 C  CG2  . THR A 1 126 ? 4.34800   -7.28400  28.23500 1.000 9.78676  ? 149 THR A CG2  1 
ATOM   1976 H  H    . THR A 1 126 ? 0.83600   -5.64500  28.72400 1.000 10.85894 ? 149 THR A H    1 
ATOM   1977 H  HA   . THR A 1 126 ? 1.75700   -7.94500  27.89100 1.000 11.28772 ? 149 THR A HA   1 
ATOM   1978 H  HB   . THR A 1 126 ? 3.19100   -5.82900  29.07400 1.000 12.29840 ? 149 THR A HB   1 
ATOM   1979 H  HG1  . THR A 1 126 ? 2.32500   -5.15000  27.19300 1.000 12.34856 ? 149 THR A HG1  1 
ATOM   1980 H  HG21 . THR A 1 126 ? 5.10300   -6.70800  28.03400 1.000 11.74216 ? 149 THR A HG21 1 
ATOM   1981 H  HG22 . THR A 1 126 ? 4.51800   -7.74400  29.07200 1.000 11.74216 ? 149 THR A HG22 1 
ATOM   1982 H  HG23 . THR A 1 126 ? 4.25700   -7.94200  27.52800 1.000 11.74216 ? 149 THR A HG23 1 
ATOM   1983 N  N    . ALA A 1 127 ? 1.82000   -7.58300  31.07600 1.000 9.57181  ? 150 ALA A N    1 
ATOM   1984 C  CA   . ALA A 1 127 ? 1.94100   -8.34400  32.31300 1.000 9.83562  ? 150 ALA A CA   1 
ATOM   1985 C  C    . ALA A 1 127 ? 0.91500   -9.46500  32.37900 1.000 9.94611  ? 150 ALA A C    1 
ATOM   1986 O  O    . ALA A 1 127 ? 1.19600   -10.53200 32.94300 1.000 10.20178 ? 150 ALA A O    1 
ATOM   1987 C  CB   . ALA A 1 127 ? 1.77900   -7.41700  33.52400 1.000 10.61088 ? 150 ALA A CB   1 
ATOM   1988 H  H    . ALA A 1 127 ? 1.61200   -6.75600  31.18300 1.000 11.48423 ? 150 ALA A H    1 
ATOM   1989 H  HA   . ALA A 1 127 ? 2.82800   -8.73600  32.34900 1.000 11.80080 ? 150 ALA A HA   1 
ATOM   1990 H  HB1  . ALA A 1 127 ? 1.83000   -7.94700  34.33500 1.000 12.73111 ? 150 ALA A HB1  1 
ATOM   1991 H  HB2  . ALA A 1 127 ? 2.49100   -6.75800  33.51400 1.000 12.73111 ? 150 ALA A HB2  1 
ATOM   1992 H  HB3  . ALA A 1 127 ? 0.91800   -6.97500  33.47000 1.000 12.73111 ? 150 ALA A HB3  1 
ATOM   1993 N  N    . PHE A 1 128 ? -0.27900  -9.24600  31.82200 1.000 9.85411  ? 151 PHE A N    1 
ATOM   1994 C  CA   . PHE A 1 128 ? -1.27800  -10.30200 31.75800 1.000 10.09066 ? 151 PHE A CA   1 
ATOM   1995 C  C    . PHE A 1 128 ? -0.79300  -11.44800 30.87800 1.000 10.02731 ? 151 PHE A C    1 
ATOM   1996 O  O    . PHE A 1 128 ? -0.89800  -12.62000 31.24700 1.000 10.23516 ? 151 PHE A O    1 
ATOM   1997 C  CB   . PHE A 1 128 ? -2.59800  -9.72100  31.24500 1.000 10.15142 ? 151 PHE A CB   1 
ATOM   1998 C  CG   . PHE A 1 128 ? -3.60100  -10.76600 30.86700 1.000 11.52925 ? 151 PHE A CG   1 
ATOM   1999 C  CD1  . PHE A 1 128 ? -4.20400  -11.56300 31.82000 1.000 13.12509 ? 151 PHE A CD1  1 
ATOM   2000 C  CD2  . PHE A 1 128 ? -3.92900  -10.96800 29.54500 1.000 12.17097 ? 151 PHE A CD2  1 
ATOM   2001 C  CE1  . PHE A 1 128 ? -5.12600  -12.53500 31.44700 1.000 14.03953 ? 151 PHE A CE1  1 
ATOM   2002 C  CE2  . PHE A 1 128 ? -4.84300  -11.94100 29.18600 1.000 14.02008 ? 151 PHE A CE2  1 
ATOM   2003 C  CZ   . PHE A 1 128 ? -5.43800  -12.71400 30.14300 1.000 13.40819 ? 151 PHE A CZ   1 
ATOM   2004 H  H    . PHE A 1 128 ? -0.53000  -8.49900  31.47700 1.000 11.82298 ? 151 PHE A H    1 
ATOM   2005 H  HA   . PHE A 1 128 ? -1.43900  -10.66100 32.64400 1.000 12.10684 ? 151 PHE A HA   1 
ATOM   2006 H  HB2  . PHE A 1 128 ? -2.99000  -9.17100  31.94100 1.000 12.17975 ? 151 PHE A HB2  1 
ATOM   2007 H  HB3  . PHE A 1 128 ? -2.41800  -9.18300  30.45800 1.000 12.17975 ? 151 PHE A HB3  1 
ATOM   2008 H  HD1  . PHE A 1 128 ? -3.99100  -11.45000 32.71900 1.000 15.74816 ? 151 PHE A HD1  1 
ATOM   2009 H  HD2  . PHE A 1 128 ? -3.53100  -10.44500 28.88700 1.000 14.60322 ? 151 PHE A HD2  1 
ATOM   2010 H  HE1  . PHE A 1 128 ? -5.53000  -13.06400 32.09700 1.000 16.84549 ? 151 PHE A HE1  1 
ATOM   2011 H  HE2  . PHE A 1 128 ? -5.05400  -12.07000 28.29000 1.000 16.82215 ? 151 PHE A HE2  1 
ATOM   2012 H  HZ   . PHE A 1 128 ? -6.05700  -13.36300 29.89700 1.000 16.08787 ? 151 PHE A HZ   1 
ATOM   2013 N  N    . ALA A 1 129 ? -0.22700  -11.13100 29.71800 1.000 9.75585  ? 152 ALA A N    1 
ATOM   2014 C  CA   . ALA A 1 129 ? 0.36300   -12.17700 28.88700 1.000 9.32255  ? 152 ALA A CA   1 
ATOM   2015 C  C    . ALA A 1 129 ? 1.39100   -12.98800 29.66400 1.000 10.29427 ? 152 ALA A C    1 
ATOM   2016 O  O    . ALA A 1 129 ? 1.39900   -14.22300 29.61800 1.000 10.27390 ? 152 ALA A O    1 
ATOM   2017 C  CB   . ALA A 1 129 ? 0.99000   -11.56000 27.63600 1.000 10.18930 ? 152 ALA A CB   1 
ATOM   2018 H  H    . ALA A 1 129 ? -0.17200  -10.33600 29.39400 1.000 11.70507 ? 152 ALA A H    1 
ATOM   2019 H  HA   . ALA A 1 129 ? -0.33900  -12.78200 28.60300 1.000 11.18512 ? 152 ALA A HA   1 
ATOM   2020 H  HB1  . ALA A 1 129 ? 1.31900   -12.27100 27.06400 1.000 12.22521 ? 152 ALA A HB1  1 
ATOM   2021 H  HB2  . ALA A 1 129 ? 0.31600   -11.04400 27.16700 1.000 12.22521 ? 152 ALA A HB2  1 
ATOM   2022 H  HB3  . ALA A 1 129 ? 1.72300   -10.98300 27.90100 1.000 12.22521 ? 152 ALA A HB3  1 
ATOM   2023 N  N    . ARG A 1 130 ? 2.26500   -12.29800 30.40500 1.000 10.07516 ? 153 ARG A N    1 
ATOM   2024 C  CA   . ARG A 1 130 ? 3.27800   -12.99500 31.19600 1.000 10.77558 ? 153 ARG A CA   1 
ATOM   2025 C  C    . ARG A 1 130 ? 2.62900   -13.91600 32.21600 1.000 10.09348 ? 153 ARG A C    1 
ATOM   2026 O  O    . ARG A 1 130 ? 3.09700   -15.03900 32.43700 1.000 11.15407 ? 153 ARG A O    1 
ATOM   2027 C  CB   . ARG A 1 130 ? 4.19200   -11.99100 31.90600 1.000 10.73634 ? 153 ARG A CB   1 
ATOM   2028 C  CG   . ARG A 1 130 ? 5.00800   -11.08400 31.01300 1.000 11.46682 ? 153 ARG A CG   1 
ATOM   2029 C  CD   . ARG A 1 130 ? 6.12500   -11.83000 30.29800 1.000 12.20078 ? 153 ARG A CD   1 
ATOM   2030 N  NE   . ARG A 1 130 ? 6.80800   -10.96200 29.35300 1.000 12.56864 ? 153 ARG A NE   1 
ATOM   2031 C  CZ   . ARG A 1 130 ? 6.33400   -10.63700 28.15800 1.000 11.86368 ? 153 ARG A CZ   1 
ATOM   2032 N  NH1  . ARG A 1 130 ? 5.28100   -11.25000 27.63800 1.000 11.04789 ? 153 ARG A NH1  1 
ATOM   2033 N  NH2  . ARG A 1 130 ? 6.92400   -9.65400  27.48100 1.000 12.90612 ? 153 ARG A NH2  1 
ATOM   2034 H  H    . ARG A 1 130 ? 2.29100   -11.44100 30.46400 1.000 12.08824 ? 153 ARG A H    1 
ATOM   2035 H  HA   . ARG A 1 130 ? 3.82400   -13.52700 30.59600 1.000 12.92875 ? 153 ARG A HA   1 
ATOM   2036 H  HB2  . ARG A 1 130 ? 3.64000   -11.42100 32.46400 1.000 12.88166 ? 153 ARG A HB2  1 
ATOM   2037 H  HB3  . ARG A 1 130 ? 4.81800   -12.48800 32.45600 1.000 12.88166 ? 153 ARG A HB3  1 
ATOM   2038 H  HG2  . ARG A 1 130 ? 4.42800   -10.69300 30.34100 1.000 13.75824 ? 153 ARG A HG2  1 
ATOM   2039 H  HG3  . ARG A 1 130 ? 5.41000   -10.38400 31.55100 1.000 13.75824 ? 153 ARG A HG3  1 
ATOM   2040 H  HD2  . ARG A 1 130 ? 6.77100   -12.14600 30.94800 1.000 14.63899 ? 153 ARG A HD2  1 
ATOM   2041 H  HD3  . ARG A 1 130 ? 5.75100   -12.58100 29.81000 1.000 14.63899 ? 153 ARG A HD3  1 
ATOM   2042 H  HE   . ARG A 1 130 ? 7.57000   -10.63700 29.58500 1.000 15.08042 ? 153 ARG A HE   1 
ATOM   2043 H  HH11 . ARG A 1 130 ? 4.88700   -11.87600 28.07800 1.000 13.25551 ? 153 ARG A HH11 1 
ATOM   2044 H  HH12 . ARG A 1 130 ? 4.99100   -11.02300 26.86100 1.000 13.25551 ? 153 ARG A HH12 1 
ATOM   2045 H  HH21 . ARG A 1 130 ? 7.59900   -9.24300  27.82000 1.000 15.48540 ? 153 ARG A HH21 1 
ATOM   2046 H  HH22 . ARG A 1 130 ? 6.63000   -9.43100  26.70400 1.000 15.48540 ? 153 ARG A HH22 1 
ATOM   2047 N  N    A GLN A 1 131 ? 1.55300   -13.44800 32.84800 0.326 10.81815 ? 154 GLN A N    1 
ATOM   2048 N  N    B GLN A 1 131 ? 1.55600   -13.45200 32.86400 0.674 10.22939 ? 154 GLN A N    1 
ATOM   2049 C  CA   A GLN A 1 131 ? 0.84100   -14.23800 33.84800 0.326 11.82283 ? 154 GLN A CA   1 
ATOM   2050 C  CA   B GLN A 1 131 ? 0.88000   -14.28200 33.86200 0.674 10.74196 ? 154 GLN A CA   1 
ATOM   2051 C  C    A GLN A 1 131 ? 0.31000   -15.53800 33.25900 0.326 11.69235 ? 154 GLN A C    1 
ATOM   2052 C  C    B GLN A 1 131 ? 0.35400   -15.57100 33.24600 0.674 11.12070 ? 154 GLN A C    1 
ATOM   2053 O  O    A GLN A 1 131 ? 0.20400   -16.54400 33.97100 0.326 12.45531 ? 154 GLN A O    1 
ATOM   2054 O  O    B GLN A 1 131 ? 0.29900   -16.60400 33.92400 0.674 12.19647 ? 154 GLN A O    1 
ATOM   2055 C  CB   A GLN A 1 131 ? -0.27500  -13.35200 34.40300 0.326 13.36804 ? 154 GLN A CB   1 
ATOM   2056 C  CB   B GLN A 1 131 ? -0.24900  -13.47800 34.51000 0.674 12.01245 ? 154 GLN A CB   1 
ATOM   2057 C  CG   A GLN A 1 131 ? -1.35500  -13.99300 35.22100 0.326 15.16772 ? 154 GLN A CG   1 
ATOM   2058 C  CG   B GLN A 1 131 ? -0.95800  -14.18800 35.63200 0.674 14.50549 ? 154 GLN A CG   1 
ATOM   2059 C  CD   A GLN A 1 131 ? -2.48400  -13.00500 35.45100 0.326 16.01720 ? 154 GLN A CD   1 
ATOM   2060 C  CD   B GLN A 1 131 ? -1.99900  -13.32400 36.32200 0.674 15.84222 ? 154 GLN A CD   1 
ATOM   2061 O  OE1  A GLN A 1 131 ? -2.25100  -11.80000 35.55500 0.326 15.62751 ? 154 GLN A OE1  1 
ATOM   2062 O  OE1  B GLN A 1 131 ? -2.10600  -12.12000 36.06700 0.674 17.63834 ? 154 GLN A OE1  1 
ATOM   2063 N  NE2  A GLN A 1 131 ? -3.71000  -13.49900 35.48600 0.326 15.71540 ? 154 GLN A NE2  1 
ATOM   2064 N  NE2  B GLN A 1 131 ? -2.76000  -13.93700 37.22400 0.674 18.05448 ? 154 GLN A NE2  1 
ATOM   2065 H  H    A GLN A 1 131 ? 1.21200   -12.66900 32.71500 0.326 12.97983 ? 154 GLN A H    1 
ATOM   2066 H  H    B GLN A 1 131 ? 1.20600   -12.67600 32.74500 0.674 12.27332 ? 154 GLN A H    1 
ATOM   2067 H  HA   A GLN A 1 131 ? 1.42500   -14.50100 34.57700 0.326 14.18545 ? 154 GLN A HA   1 
ATOM   2068 H  HA   B GLN A 1 131 ? 1.50700   -14.52900 34.55900 0.674 12.88841 ? 154 GLN A HA   1 
ATOM   2069 H  HB2  A GLN A 1 131 ? 0.13800   -12.68000 34.96800 0.326 16.03970 ? 154 GLN A HB2  1 
ATOM   2070 H  HB2  B GLN A 1 131 ? 0.12300   -12.65800 34.87100 0.674 14.41299 ? 154 GLN A HB2  1 
ATOM   2071 H  HB3  A GLN A 1 131 ? -0.71400  -12.92700 33.64900 0.326 16.03970 ? 154 GLN A HB3  1 
ATOM   2072 H  HB3  B GLN A 1 131 ? -0.91000  -13.27100 33.83100 0.674 14.41299 ? 154 GLN A HB3  1 
ATOM   2073 H  HG2  A GLN A 1 131 ? -1.70700  -14.76500 34.75100 0.326 18.19931 ? 154 GLN A HG2  1 
ATOM   2074 H  HG2  B GLN A 1 131 ? -1.40900  -14.97000 35.27500 0.674 17.40463 ? 154 GLN A HG2  1 
ATOM   2075 H  HG3  A GLN A 1 131 ? -0.99700  -14.26300 36.08100 0.326 18.19931 ? 154 GLN A HG3  1 
ATOM   2076 H  HG3  B GLN A 1 131 ? -0.30500  -14.45700 36.29700 0.674 17.40463 ? 154 GLN A HG3  1 
ATOM   2077 H  HE21 A GLN A 1 131 ? -3.83600  -14.34300 35.38000 0.326 18.85653 ? 154 GLN A HE21 1 
ATOM   2078 H  HE21 B GLN A 1 131 ? -2.64700  -14.77400 37.38500 0.674 21.66343 ? 154 GLN A HE21 1 
ATOM   2079 H  HE22 A GLN A 1 131 ? -4.38000  -12.97600 35.61300 0.326 18.85653 ? 154 GLN A HE22 1 
ATOM   2080 H  HE22 B GLN A 1 131 ? -3.36600  -13.49600 37.64600 0.674 21.66343 ? 154 GLN A HE22 1 
ATOM   2081 N  N    . LEU A 1 132 ? -0.02100  -15.54300 31.96700 1.000 11.11523 ? 155 LEU A N    1 
ATOM   2082 C  CA   . LEU A 1 132 ? -0.47400  -16.74200 31.28000 1.000 10.83455 ? 155 LEU A CA   1 
ATOM   2083 C  C    . LEU A 1 132 ? 0.65900   -17.68000 30.87200 1.000 11.44193 ? 155 LEU A C    1 
ATOM   2084 O  O    . LEU A 1 132 ? 0.37600   -18.79800 30.42800 1.000 13.89842 ? 155 LEU A O    1 
ATOM   2085 C  CB   . LEU A 1 132 ? -1.21500  -16.35600 29.99800 1.000 12.47156 ? 155 LEU A CB   1 
ATOM   2086 C  CG   . LEU A 1 132 ? -2.49100  -15.53900 30.17300 1.000 13.46153 ? 155 LEU A CG   1 
ATOM   2087 C  CD1  . LEU A 1 132 ? -3.16200  -15.37000 28.83500 1.000 15.16712 ? 155 LEU A CD1  1 
ATOM   2088 C  CD2  . LEU A 1 132 ? -3.44800  -16.18200 31.17400 1.000 14.75250 ? 155 LEU A CD2  1 
ATOM   2089 H  H    . LEU A 1 132 ? -0.02000  -14.83600 31.47600 1.000 13.33632 ? 155 LEU A H    1 
ATOM   2090 H  HA   . LEU A 1 132 ? -1.07000  -17.21300 31.88300 1.000 12.99951 ? 155 LEU A HA   1 
ATOM   2091 H  HB2  . LEU A 1 132 ? -0.61300  -15.83000 29.44800 1.000 14.96392 ? 155 LEU A HB2  1 
ATOM   2092 H  HB3  . LEU A 1 132 ? -1.46000  -17.17200 29.53400 1.000 14.96392 ? 155 LEU A HB3  1 
ATOM   2093 H  HG   . LEU A 1 132 ? -2.25900  -14.66700 30.53100 1.000 16.15189 ? 155 LEU A HG   1 
ATOM   2094 H  HD11 . LEU A 1 132 ? -3.98600  -14.87100 28.95500 1.000 18.19859 ? 155 LEU A HD11 1 
ATOM   2095 H  HD12 . LEU A 1 132 ? -2.56600  -14.88600 28.24100 1.000 18.19859 ? 155 LEU A HD12 1 
ATOM   2096 H  HD13 . LEU A 1 132 ? -3.35700  -16.24600 28.46600 1.000 18.19859 ? 155 LEU A HD13 1 
ATOM   2097 H  HD21 . LEU A 1 132 ? -4.28300  -15.69000 31.17400 1.000 17.70105 ? 155 LEU A HD21 1 
ATOM   2098 H  HD22 . LEU A 1 132 ? -3.60600  -17.10300 30.91100 1.000 17.70105 ? 155 LEU A HD22 1 
ATOM   2099 H  HD23 . LEU A 1 132 ? -3.04700  -16.15400 32.05700 1.000 17.70105 ? 155 LEU A HD23 1 
ATOM   2100 N  N    . GLY A 1 133 ? 1.90900   -17.25100 30.96600 1.000 11.08640 ? 156 GLY A N    1 
ATOM   2101 C  CA   . GLY A 1 133 ? 3.03500   -18.02500 30.49800 1.000 11.39890 ? 156 GLY A CA   1 
ATOM   2102 C  C    . GLY A 1 133 ? 3.55000   -17.64400 29.12500 1.000 10.42379 ? 156 GLY A C    1 
ATOM   2103 O  O    . GLY A 1 133 ? 4.36100   -18.38900 28.56300 1.000 12.69009 ? 156 GLY A O    1 
ATOM   2104 H  H    . GLY A 1 133 ? 2.13200   -16.49400 31.30800 1.000 13.30173 ? 156 GLY A H    1 
ATOM   2105 H  HA2  . GLY A 1 133 ? 3.76500   -17.92100 31.12700 1.000 13.67674 ? 156 GLY A HA2  1 
ATOM   2106 H  HA3  . GLY A 1 133 ? 2.77600   -18.96000 30.46700 1.000 13.67674 ? 156 GLY A HA3  1 
ATOM   2107 N  N    . ASP A 1 134 ? 3.10000   -16.51200 28.57100 1.000 10.52338 ? 157 ASP A N    1 
ATOM   2108 C  CA   . ASP A 1 134 ? 3.56700   -16.00400 27.28600 1.000 10.30089 ? 157 ASP A CA   1 
ATOM   2109 C  C    . ASP A 1 134 ? 4.61700   -14.95000 27.59900 1.000 10.29012 ? 157 ASP A C    1 
ATOM   2110 O  O    . ASP A 1 134 ? 4.29900   -13.86600 28.11500 1.000 10.72883 ? 157 ASP A O    1 
ATOM   2111 C  CB   . ASP A 1 134 ? 2.39700   -15.41400 26.51200 1.000 9.88533  ? 157 ASP A CB   1 
ATOM   2112 C  CG   . ASP A 1 134 ? 2.77900   -14.92000 25.12300 1.000 10.10267 ? 157 ASP A CG   1 
ATOM   2113 O  OD1  . ASP A 1 134 ? 3.93300   -14.51400 24.91800 1.000 9.99478  ? 157 ASP A OD1  1 
ATOM   2114 O  OD2  . ASP A 1 134 ? 1.88600   -14.93500 24.24900 1.000 10.62771 ? 157 ASP A OD2  1 
ATOM   2115 H  H    . ASP A 1 134 ? 2.50400   -16.01000 28.93500 1.000 12.62611 ? 157 ASP A H    1 
ATOM   2116 H  HA   . ASP A 1 134 ? 3.96600   -16.70400 26.74600 1.000 12.35912 ? 157 ASP A HA   1 
ATOM   2117 H  HB2  . ASP A 1 134 ? 1.71400   -16.09500 26.40800 1.000 11.86044 ? 157 ASP A HB2  1 
ATOM   2118 H  HB3  . ASP A 1 134 ? 2.04100   -14.66000 27.00800 1.000 11.86044 ? 157 ASP A HB3  1 
ATOM   2119 N  N    . GLU A 1 135 ? 5.86800   -15.30500 27.36900 1.000 10.57765 ? 158 GLU A N    1 
ATOM   2120 C  CA   . GLU A 1 135 ? 6.99900   -14.44200 27.64700 1.000 10.54460 ? 158 GLU A CA   1 
ATOM   2121 C  C    . GLU A 1 135 ? 7.53000   -13.78400 26.37900 1.000 11.38390 ? 158 GLU A C    1 
ATOM   2122 O  O    . GLU A 1 135 ? 8.61300   -13.21000 26.40100 1.000 15.54023 ? 158 GLU A O    1 
ATOM   2123 C  CB   . GLU A 1 135 ? 8.04600   -15.23100 28.46600 1.000 13.96577 ? 158 GLU A CB   1 
ATOM   2124 C  CG   . GLU A 1 135 ? 7.42400   -15.68400 29.82000 1.000 15.38669 ? 158 GLU A CG   1 
ATOM   2125 C  CD   . GLU A 1 135 ? 8.37600   -16.30200 30.85300 1.000 16.58153 ? 158 GLU A CD   1 
ATOM   2126 O  OE1  . GLU A 1 135 ? 9.55700   -16.55600 30.53900 1.000 17.90415 ? 158 GLU A OE1  1 
ATOM   2127 O  OE2  . GLU A 1 135 ? 7.92200   -16.55700 32.00200 1.000 18.40121 ? 158 GLU A OE2  1 
ATOM   2128 H  H    . GLU A 1 135 ? 6.09400   -16.06800 27.04100 1.000 12.69122 ? 158 GLU A H    1 
ATOM   2129 H  HA   . GLU A 1 135 ? 6.75400   -13.69800 28.21900 1.000 12.65157 ? 158 GLU A HA   1 
ATOM   2130 H  HB2  . GLU A 1 135 ? 8.32400   -16.01700 27.97100 1.000 16.75697 ? 158 GLU A HB2  1 
ATOM   2131 H  HB3  . GLU A 1 135 ? 8.81300   -14.66500 28.64700 1.000 16.75697 ? 158 GLU A HB3  1 
ATOM   2132 H  HG2  . GLU A 1 135 ? 7.02100   -14.90700 30.23900 1.000 18.46208 ? 158 GLU A HG2  1 
ATOM   2133 H  HG3  . GLU A 1 135 ? 6.74400   -16.34900 29.63000 1.000 18.46208 ? 158 GLU A HG3  1 
ATOM   2134 N  N    . THR A 1 136 ? 6.76200   -13.81800 25.28500 1.000 10.45819 ? 159 THR A N    1 
ATOM   2135 C  CA   . THR A 1 136 ? 7.15200   -13.26100 23.99300 1.000 11.21093 ? 159 THR A CA   1 
ATOM   2136 C  C    . THR A 1 136 ? 6.34100   -12.02500 23.63100 1.000 10.14953 ? 159 THR A C    1 
ATOM   2137 O  O    . THR A 1 136 ? 6.89700   -11.02100 23.17300 1.000 11.04118 ? 159 THR A O    1 
ATOM   2138 C  CB   . THR A 1 136 ? 6.97100   -14.34300 22.91000 1.000 11.70992 ? 159 THR A CB   1 
ATOM   2139 O  OG1  . THR A 1 136 ? 7.66700   -15.53900 23.28800 1.000 12.77560 ? 159 THR A OG1  1 
ATOM   2140 C  CG2  . THR A 1 136 ? 7.52300   -13.87000 21.55400 1.000 11.97862 ? 159 THR A CG2  1 
ATOM   2141 H  H    . THR A 1 136 ? 5.97900   -14.17300 25.27000 1.000 12.54788 ? 159 THR A H    1 
ATOM   2142 H  HA   . THR A 1 136 ? 8.08700   -13.00100 24.01600 1.000 13.45116 ? 159 THR A HA   1 
ATOM   2143 H  HB   . THR A 1 136 ? 6.02400   -14.52600 22.81600 1.000 14.04995 ? 159 THR A HB   1 
ATOM   2144 H  HG1  . THR A 1 136 ? 8.48700   -15.37900 23.37600 1.000 15.32878 ? 159 THR A HG1  1 
ATOM   2145 H  HG21 . THR A 1 136 ? 7.45100   -14.58300 20.90000 1.000 14.37240 ? 159 THR A HG21 1 
ATOM   2146 H  HG22 . THR A 1 136 ? 7.01900   -13.10300 21.24000 1.000 14.37240 ? 159 THR A HG22 1 
ATOM   2147 H  HG23 . THR A 1 136 ? 8.45500   -13.61900 21.64400 1.000 14.37240 ? 159 THR A HG23 1 
ATOM   2148 N  N    . PHE A 1 137 ? 5.02700   -12.08700 23.82200 1.000 9.58469  ? 160 PHE A N    1 
ATOM   2149 C  CA   . PHE A 1 137 ? 4.12800   -10.97300 23.52900 1.000 9.36274  ? 160 PHE A CA   1 
ATOM   2150 C  C    . PHE A 1 137 ? 4.61600   -9.68900  24.18400 1.000 9.80358  ? 160 PHE A C    1 
ATOM   2151 O  O    . PHE A 1 137 ? 4.94100   -9.66300  25.37400 1.000 10.25056 ? 160 PHE A O    1 
ATOM   2152 C  CB   . PHE A 1 137 ? 2.74800   -11.33100 24.08800 1.000 9.48252  ? 160 PHE A CB   1 
ATOM   2153 C  CG   . PHE A 1 137 ? 1.70200   -10.24600 23.98700 1.000 9.10801  ? 160 PHE A CG   1 
ATOM   2154 C  CD1  . PHE A 1 137 ? 1.62500   -9.22300  24.92900 1.000 9.51155  ? 160 PHE A CD1  1 
ATOM   2155 C  CD2  . PHE A 1 137 ? 0.77100   -10.26900 22.96700 1.000 9.88090  ? 160 PHE A CD2  1 
ATOM   2156 C  CE1  . PHE A 1 137 ? 0.63900   -8.24900  24.84700 1.000 9.70828  ? 160 PHE A CE1  1 
ATOM   2157 C  CE2  . PHE A 1 137 ? -0.20100  -9.29900  22.86800 1.000 9.67380  ? 160 PHE A CE2  1 
ATOM   2158 C  CZ   . PHE A 1 137 ? -0.28200  -8.28600  23.81300 1.000 9.76190  ? 160 PHE A CZ   1 
ATOM   2159 H  H    . PHE A 1 137 ? 4.61900   -12.77900 24.12700 1.000 11.49968 ? 160 PHE A H    1 
ATOM   2160 H  HA   . PHE A 1 137 ? 4.08200   -10.82200 22.57200 1.000 11.23334 ? 160 PHE A HA   1 
ATOM   2161 H  HB2  . PHE A 1 137 ? 2.41300   -12.10100 23.60100 1.000 11.37708 ? 160 PHE A HB2  1 
ATOM   2162 H  HB3  . PHE A 1 137 ? 2.84600   -11.55000 25.02700 1.000 11.37708 ? 160 PHE A HB3  1 
ATOM   2163 H  HD1  . PHE A 1 137 ? 2.24200   -9.19200  25.62300 1.000 11.41192 ? 160 PHE A HD1  1 
ATOM   2164 H  HD2  . PHE A 1 137 ? 0.80100   -10.95200 22.33600 1.000 11.85514 ? 160 PHE A HD2  1 
ATOM   2165 H  HE1  . PHE A 1 137 ? 0.59600   -7.57400  25.48500 1.000 11.64799 ? 160 PHE A HE1  1 
ATOM   2166 H  HE2  . PHE A 1 137 ? -0.80800  -9.32200  22.16400 1.000 11.60661 ? 160 PHE A HE2  1 
ATOM   2167 H  HZ   . PHE A 1 137 ? -0.94600  -7.63800  23.75300 1.000 11.71233 ? 160 PHE A HZ   1 
ATOM   2168 N  N    . ARG A 1 138 ? 4.61900   -8.59600  23.42700 1.000 9.49936  ? 161 ARG A N    1 
ATOM   2169 C  CA   . ARG A 1 138 ? 4.80600   -7.28200  24.03300 1.000 10.12948 ? 161 ARG A CA   1 
ATOM   2170 C  C    . ARG A 1 138 ? 3.88500   -6.28400  23.35800 1.000 9.74570  ? 161 ARG A C    1 
ATOM   2171 O  O    . ARG A 1 138 ? 3.91000   -6.14200  22.13200 1.000 11.10013 ? 161 ARG A O    1 
ATOM   2172 C  CB   . ARG A 1 138 ? 6.26600   -6.81500  24.00800 1.000 11.33366 ? 161 ARG A CB   1 
ATOM   2173 C  CG   . ARG A 1 138 ? 6.92100   -6.85000  22.64200 1.000 11.92282 ? 161 ARG A CG   1 
ATOM   2174 C  CD   . ARG A 1 138 ? 8.40100   -6.52200  22.72800 1.000 11.41053 ? 161 ARG A CD   1 
ATOM   2175 N  NE   . ARG A 1 138 ? 8.62900   -5.11100  23.00800 1.000 10.88715 ? 161 ARG A NE   1 
ATOM   2176 C  CZ   . ARG A 1 138 ? 9.82700   -4.54900  23.01500 1.000 12.08008 ? 161 ARG A CZ   1 
ATOM   2177 N  NH1  . ARG A 1 138 ? 10.92600  -5.27200  22.91600 1.000 14.29952 ? 161 ARG A NH1  1 
ATOM   2178 N  NH2  . ARG A 1 138 ? 9.92600   -3.22800  23.11000 1.000 14.01000 ? 161 ARG A NH2  1 
ATOM   2179 H  H    . ARG A 1 138 ? 4.51600   -8.59000  22.57300 1.000 11.39729 ? 161 ARG A H    1 
ATOM   2180 H  HA   . ARG A 1 138 ? 4.54800   -7.33800  24.96700 1.000 12.15343 ? 161 ARG A HA   1 
ATOM   2181 H  HB2  . ARG A 1 138 ? 6.30200   -5.89900  24.32500 1.000 13.59844 ? 161 ARG A HB2  1 
ATOM   2182 H  HB3  . ARG A 1 138 ? 6.78300   -7.38900  24.59400 1.000 13.59844 ? 161 ARG A HB3  1 
ATOM   2183 H  HG2  . ARG A 1 138 ? 6.82600   -7.73700  22.26200 1.000 14.30544 ? 161 ARG A HG2  1 
ATOM   2184 H  HG3  . ARG A 1 138 ? 6.49700   -6.19500  22.06500 1.000 14.30544 ? 161 ARG A HG3  1 
ATOM   2185 H  HD2  . ARG A 1 138 ? 8.80200   -7.04200  23.44200 1.000 13.69069 ? 161 ARG A HD2  1 
ATOM   2186 H  HD3  . ARG A 1 138 ? 8.82500   -6.73600  21.88200 1.000 13.69069 ? 161 ARG A HD3  1 
ATOM   2187 H  HE   . ARG A 1 138 ? 7.94700   -4.61500  23.17900 1.000 13.06263 ? 161 ARG A HE   1 
ATOM   2188 H  HH11 . ARG A 1 138 ? 10.87300  -6.12700  22.84600 1.000 17.15748 ? 161 ARG A HH11 1 
ATOM   2189 H  HH12 . ARG A 1 138 ? 11.69500  -4.88800  22.92300 1.000 17.15748 ? 161 ARG A HH12 1 
ATOM   2190 H  HH21 . ARG A 1 138 ? 9.21500   -2.74700  23.16600 1.000 16.81005 ? 161 ARG A HH21 1 
ATOM   2191 H  HH22 . ARG A 1 138 ? 10.70000  -2.85300  23.11500 1.000 16.81005 ? 161 ARG A HH22 1 
ATOM   2192 N  N    . LEU A 1 139 ? 3.06300   -5.62000  24.15600 1.000 9.57901  ? 162 LEU A N    1 
ATOM   2193 C  CA   . LEU A 1 139 ? 2.30100   -4.46000  23.72600 1.000 9.70093  ? 162 LEU A CA   1 
ATOM   2194 C  C    . LEU A 1 139 ? 2.96800   -3.24900  24.34600 1.000 10.39820 ? 162 LEU A C    1 
ATOM   2195 O  O    . LEU A 1 139 ? 3.03800   -3.12800  25.57900 1.000 11.12431 ? 162 LEU A O    1 
ATOM   2196 C  CB   . LEU A 1 139 ? 0.83700   -4.56200  24.14700 1.000 10.78637 ? 162 LEU A CB   1 
ATOM   2197 C  CG   . LEU A 1 139 ? -0.08400  -3.51600  23.50900 1.000 10.22094 ? 162 LEU A CG   1 
ATOM   2198 C  CD1  . LEU A 1 139 ? -0.16900  -3.73300  21.99100 1.000 12.47380 ? 162 LEU A CD1  1 
ATOM   2199 C  CD2  . LEU A 1 139 ? -1.47600  -3.52800  24.10100 1.000 11.68292 ? 162 LEU A CD2  1 
ATOM   2200 H  H    . LEU A 1 139 ? 2.92500   -5.83000  24.97900 1.000 11.49286 ? 162 LEU A H    1 
ATOM   2201 H  HA   . LEU A 1 139 ? 2.30900   -4.38100  22.75900 1.000 11.63917 ? 162 LEU A HA   1 
ATOM   2202 H  HB2  . LEU A 1 139 ? 0.50500   -5.43800  23.89600 1.000 12.94170 ? 162 LEU A HB2  1 
ATOM   2203 H  HB3  . LEU A 1 139 ? 0.78500   -4.45100  25.10900 1.000 12.94170 ? 162 LEU A HB3  1 
ATOM   2204 H  HG   . LEU A 1 139 ? 0.30000   -2.64500  23.69200 1.000 12.26318 ? 162 LEU A HG   1 
ATOM   2205 H  HD11 . LEU A 1 139 ? -0.85000  -3.14700  21.62600 1.000 14.96661 ? 162 LEU A HD11 1 
ATOM   2206 H  HD12 . LEU A 1 139 ? 0.69100   -3.52900  21.59400 1.000 14.96661 ? 162 LEU A HD12 1 
ATOM   2207 H  HD13 . LEU A 1 139 ? -0.40300  -4.65900  21.81700 1.000 14.96661 ? 162 LEU A HD13 1 
ATOM   2208 H  HD21 . LEU A 1 139 ? -1.99600  -2.81400  23.70000 1.000 14.01755 ? 162 LEU A HD21 1 
ATOM   2209 H  HD22 . LEU A 1 139 ? -1.89200  -4.38500  23.91300 1.000 14.01755 ? 162 LEU A HD22 1 
ATOM   2210 H  HD23 . LEU A 1 139 ? -1.41300  -3.39400  25.05900 1.000 14.01755 ? 162 LEU A HD23 1 
ATOM   2211 N  N    . ASP A 1 140 ? 3.48500   -2.37400  23.49100 1.000 10.28305 ? 163 ASP A N    1 
ATOM   2212 C  CA   . ASP A 1 140 ? 4.27700   -1.21200  23.87000 1.000 10.40451 ? 163 ASP A CA   1 
ATOM   2213 C  C    . ASP A 1 140 ? 3.47600   0.08100   23.83300 1.000 9.98302  ? 163 ASP A C    1 
ATOM   2214 O  O    . ASP A 1 140 ? 3.68300   0.95800   24.68000 1.000 11.87825 ? 163 ASP A O    1 
ATOM   2215 C  CB   . ASP A 1 140 ? 5.47000   -1.02500  22.90700 1.000 10.48834 ? 163 ASP A CB   1 
ATOM   2216 C  CG   . ASP A 1 140 ? 6.55200   -2.08300  23.01500 1.000 11.74337 ? 163 ASP A CG   1 
ATOM   2217 O  OD1  . ASP A 1 140 ? 6.31900   -3.28100  22.74700 1.000 11.10011 ? 163 ASP A OD1  1 
ATOM   2218 O  OD2  . ASP A 1 140 ? 7.69900   -1.65300  23.32500 1.000 12.92935 ? 163 ASP A OD2  1 
ATOM   2219 H  H    . ASP A 1 140 ? 3.38400   -2.43600  22.63900 1.000 12.33771 ? 163 ASP A H    1 
ATOM   2220 H  HA   . ASP A 1 140 ? 4.61300   -1.36700  24.76700 1.000 12.48346 ? 163 ASP A HA   1 
ATOM   2221 H  HB2  . ASP A 1 140 ? 5.13600   -1.04300  21.99700 1.000 12.58405 ? 163 ASP A HB2  1 
ATOM   2222 H  HB3  . ASP A 1 140 ? 5.88300   -0.16700  23.09300 1.000 12.58405 ? 163 ASP A HB3  1 
ATOM   2223 N  N    . ARG A 1 141 ? 2.60500   0.22300   22.83800 1.000 9.56386  ? 164 ARG A N    1 
ATOM   2224 C  CA   . ARG A 1 141 ? 1.93900   1.47000   22.50200 1.000 9.97655  ? 164 ARG A CA   1 
ATOM   2225 C  C    . ARG A 1 141 ? 0.42400   1.29500   22.45700 1.000 9.50344  ? 164 ARG A C    1 
ATOM   2226 O  O    . ARG A 1 141 ? -0.10300  0.18800   22.45200 1.000 10.27006 ? 164 ARG A O    1 
ATOM   2227 C  CB   . ARG A 1 141 ? 2.45500   2.01100   21.15500 1.000 10.02059 ? 164 ARG A CB   1 
ATOM   2228 C  CG   . ARG A 1 141 ? 3.87200   2.54200   21.23200 1.000 9.90485  ? 164 ARG A CG   1 
ATOM   2229 C  CD   . ARG A 1 141 ? 4.45000   2.90000   19.87900 1.000 10.65100 ? 164 ARG A CD   1 
ATOM   2230 N  NE   . ARG A 1 141 ? 4.67500   1.68900   19.11200 1.000 11.37034 ? 164 ARG A NE   1 
ATOM   2231 C  CZ   . ARG A 1 141 ? 5.01100   1.64200   17.83600 1.000 10.97046 ? 164 ARG A CZ   1 
ATOM   2232 N  NH1  . ARG A 1 141 ? 5.31700   2.73800   17.15400 1.000 11.66306 ? 164 ARG A NH1  1 
ATOM   2233 N  NH2  . ARG A 1 141 ? 5.05700   0.45700   17.23600 1.000 11.86201 ? 164 ARG A NH2  1 
ATOM   2234 H  H    . ARG A 1 141 ? 2.37500   -0.42300  22.31800 1.000 11.47468 ? 164 ARG A H    1 
ATOM   2235 H  HA   . ARG A 1 141 ? 2.12100   2.11600   23.20200 1.000 11.96992 ? 164 ARG A HA   1 
ATOM   2236 H  HB2  . ARG A 1 141 ? 2.44000   1.29400   20.50100 1.000 12.02276 ? 164 ARG A HB2  1 
ATOM   2237 H  HB3  . ARG A 1 141 ? 1.87900   2.73600   20.86500 1.000 12.02276 ? 164 ARG A HB3  1 
ATOM   2238 H  HG2  . ARG A 1 141 ? 3.87800   3.34300   21.78000 1.000 11.88387 ? 164 ARG A HG2  1 
ATOM   2239 H  HG3  . ARG A 1 141 ? 4.44100   1.86400   21.62900 1.000 11.88387 ? 164 ARG A HG3  1 
ATOM   2240 H  HD2  . ARG A 1 141 ? 3.82900   3.46600   19.39500 1.000 12.77925 ? 164 ARG A HD2  1 
ATOM   2241 H  HD3  . ARG A 1 141 ? 5.29700   3.36000   19.99500 1.000 12.77925 ? 164 ARG A HD3  1 
ATOM   2242 H  HE   . ARG A 1 141 ? 4.58200   0.93900   19.52200 1.000 13.64246 ? 164 ARG A HE   1 
ATOM   2243 H  HH11 . ARG A 1 141 ? 5.29900   3.50500   17.54200 1.000 13.99373 ? 164 ARG A HH11 1 
ATOM   2244 H  HH12 . ARG A 1 141 ? 5.53200   2.68100   16.32300 1.000 13.99373 ? 164 ARG A HH12 1 
ATOM   2245 H  HH21 . ARG A 1 141 ? 4.86900   -0.25600  17.67800 1.000 14.23246 ? 164 ARG A HH21 1 
ATOM   2246 H  HH22 . ARG A 1 141 ? 5.27300   0.40400   16.40500 1.000 14.23246 ? 164 ARG A HH22 1 
ATOM   2247 N  N    . THR A 1 142 ? -0.27500  2.43200   22.43700 1.000 9.81635  ? 165 THR A N    1 
ATOM   2248 C  CA   . THR A 1 142 ? -1.70900  2.50200   22.22900 1.000 9.87999  ? 165 THR A CA   1 
ATOM   2249 C  C    . THR A 1 142 ? -2.01500  2.65100   20.73300 1.000 8.97120  ? 165 THR A C    1 
ATOM   2250 O  O    . THR A 1 142 ? -1.11600  2.70700   19.89100 1.000 9.92208  ? 165 THR A O    1 
ATOM   2251 C  CB   . THR A 1 142 ? -2.25900  3.70500   22.99300 1.000 10.85322 ? 165 THR A CB   1 
ATOM   2252 O  OG1  . THR A 1 142 ? -1.58700  4.87200   22.50900 1.000 11.19561 ? 165 THR A OG1  1 
ATOM   2253 C  CG2  . THR A 1 142 ? -2.04800  3.55800   24.49900 1.000 11.47659 ? 165 THR A CG2  1 
ATOM   2254 H  H    . THR A 1 142 ? 0.08000   3.20800   22.54600 1.000 11.77767 ? 165 THR A H    1 
ATOM   2255 H  HA   . THR A 1 142 ? -2.12200  1.68500   22.55100 1.000 11.85404 ? 165 THR A HA   1 
ATOM   2256 H  HB   . THR A 1 142 ? -3.21600  3.78200   22.85700 1.000 13.02191 ? 165 THR A HB   1 
ATOM   2257 H  HG1  . THR A 1 142 ? -1.82400  5.03300   21.72000 1.000 13.43279 ? 165 THR A HG1  1 
ATOM   2258 H  HG21 . THR A 1 142 ? -2.40800  4.33200   24.96100 1.000 13.76996 ? 165 THR A HG21 1 
ATOM   2259 H  HG22 . THR A 1 142 ? -2.49900  2.76200   24.82200 1.000 13.76996 ? 165 THR A HG22 1 
ATOM   2260 H  HG23 . THR A 1 142 ? -1.10100  3.48600   24.69700 1.000 13.76996 ? 165 THR A HG23 1 
ATOM   2261 N  N    . GLU A 1 143 ? -3.30500  2.70000   20.40600 1.000 9.42762  ? 166 GLU A N    1 
ATOM   2262 C  CA   . GLU A 1 143 ? -3.73600  3.02000   19.05500 1.000 10.01952 ? 166 GLU A CA   1 
ATOM   2263 C  C    . GLU A 1 143 ? -3.65400  4.52800   18.83400 1.000 10.71592 ? 166 GLU A C    1 
ATOM   2264 O  O    . GLU A 1 143 ? -4.03800  5.30600   19.71300 1.000 10.87769 ? 166 GLU A O    1 
ATOM   2265 C  CB   . GLU A 1 143 ? -5.18600  2.58100   18.82600 1.000 10.52990 ? 166 GLU A CB   1 
ATOM   2266 C  CG   . GLU A 1 143 ? -5.45200  1.10900   18.99600 1.000 10.08079 ? 166 GLU A CG   1 
ATOM   2267 C  CD   . GLU A 1 143 ? -4.89600  0.25800   17.88300 1.000 10.47285 ? 166 GLU A CD   1 
ATOM   2268 O  OE1  . GLU A 1 143 ? -4.31200  0.79500   16.90800 1.000 11.10563 ? 166 GLU A OE1  1 
ATOM   2269 O  OE2  . GLU A 1 143 ? -5.06200  -0.99400  17.98600 1.000 11.07241 ? 166 GLU A OE2  1 
ATOM   2270 H  H    . GLU A 1 143 ? -3.95100  2.55100   20.95400 1.000 11.31120 ? 166 GLU A H    1 
ATOM   2271 H  HA   . GLU A 1 143 ? -3.16500  2.56000   18.42000 1.000 12.02148 ? 166 GLU A HA   1 
ATOM   2272 H  HB2  . GLU A 1 143 ? -5.75100  3.05100   19.45900 1.000 12.63393 ? 166 GLU A HB2  1 
ATOM   2273 H  HB3  . GLU A 1 143 ? -5.43700  2.81700   17.91900 1.000 12.63393 ? 166 GLU A HB3  1 
ATOM   2274 H  HG2  . GLU A 1 143 ? -5.04500  0.81200   19.82500 1.000 12.09500 ? 166 GLU A HG2  1 
ATOM   2275 H  HG3  . GLU A 1 143 ? -6.41000  0.96600   19.02600 1.000 12.09500 ? 166 GLU A HG3  1 
ATOM   2276 N  N    . PRO A 1 144 ? -3.23600  4.97400   17.65000 1.000 10.82928 ? 167 PRO A N    1 
ATOM   2277 C  CA   . PRO A 1 144 ? -2.95600  4.16300   16.45700 1.000 11.24333 ? 167 PRO A CA   1 
ATOM   2278 C  C    . PRO A 1 144 ? -1.49400  3.79700   16.24700 1.000 11.18477 ? 167 PRO A C    1 
ATOM   2279 O  O    . PRO A 1 144 ? -1.17000  3.09100   15.27600 1.000 12.14894 ? 167 PRO A O    1 
ATOM   2280 C  CB   . PRO A 1 144 ? -3.40000  5.10500   15.32600 1.000 12.17145 ? 167 PRO A CB   1 
ATOM   2281 C  CG   . PRO A 1 144 ? -2.98900  6.45200   15.82400 1.000 12.94890 ? 167 PRO A CG   1 
ATOM   2282 C  CD   . PRO A 1 144 ? -3.27400  6.41700   17.31300 1.000 11.34710 ? 167 PRO A CD   1 
ATOM   2283 H  HA   . PRO A 1 144 ? -3.48600  3.35200   16.51600 1.000 13.49005 ? 167 PRO A HA   1 
ATOM   2284 H  HB2  . PRO A 1 144 ? -2.94500  4.87800   14.50000 1.000 14.60379 ? 167 PRO A HB2  1 
ATOM   2285 H  HB3  . PRO A 1 144 ? -4.36100  5.05200   15.20000 1.000 14.60379 ? 167 PRO A HB3  1 
ATOM   2286 H  HG2  . PRO A 1 144 ? -2.04400  6.59400   15.65300 1.000 15.53673 ? 167 PRO A HG2  1 
ATOM   2287 H  HG3  . PRO A 1 144 ? -3.51200  7.14100   15.38600 1.000 15.53673 ? 167 PRO A HG3  1 
ATOM   2288 H  HD2  . PRO A 1 144 ? -2.59200  6.90100   17.80400 1.000 13.61457 ? 167 PRO A HD2  1 
ATOM   2289 H  HD3  . PRO A 1 144 ? -4.14800  6.79000   17.50400 1.000 13.61457 ? 167 PRO A HD3  1 
ATOM   2290 N  N    . THR A 1 145 ? -0.58800  4.26800   17.10500 1.000 10.51637 ? 168 THR A N    1 
ATOM   2291 C  CA   . THR A 1 145 ? 0.83300   4.14700   16.81700 1.000 10.86671 ? 168 THR A CA   1 
ATOM   2292 C  C    . THR A 1 145 ? 1.34900   2.72000   16.91200 1.000 10.47057 ? 168 THR A C    1 
ATOM   2293 O  O    . THR A 1 145 ? 2.40200   2.42800   16.34000 1.000 11.07199 ? 168 THR A O    1 
ATOM   2294 C  CB   . THR A 1 145 ? 1.67800   5.09300   17.67600 1.000 11.63288 ? 168 THR A CB   1 
ATOM   2295 O  OG1  . THR A 1 145 ? 1.53300   4.75800   19.06600 1.000 11.12810 ? 168 THR A OG1  1 
ATOM   2296 C  CG2  . THR A 1 145 ? 1.29100   6.55200   17.44000 1.000 12.75055 ? 168 THR A CG2  1 
ATOM   2297 H  H    . THR A 1 145 ? -0.77100  4.65500   17.85100 1.000 12.61770 ? 168 THR A H    1 
ATOM   2298 H  HA   . THR A 1 145 ? 0.95900   4.43500   15.89900 1.000 13.03810 ? 168 THR A HA   1 
ATOM   2299 H  HB   . THR A 1 145 ? 2.61000   4.99800   17.42800 1.000 13.95751 ? 168 THR A HB   1 
ATOM   2300 H  HG1  . THR A 1 145 ? 2.02600   5.25200   19.53300 1.000 13.35177 ? 168 THR A HG1  1 
ATOM   2301 H  HG21 . THR A 1 145 ? 1.84900   7.13500   17.97700 1.000 15.29871 ? 168 THR A HG21 1 
ATOM   2302 H  HG22 . THR A 1 145 ? 1.40800   6.77800   16.50400 1.000 15.29871 ? 168 THR A HG22 1 
ATOM   2303 H  HG23 . THR A 1 145 ? 0.36300   6.69300   17.68400 1.000 15.29871 ? 168 THR A HG23 1 
ATOM   2304 N  N    . LEU A 1 146 ? 0.61900   1.81200   17.57000 1.000 9.99530  ? 169 LEU A N    1 
ATOM   2305 C  CA   . LEU A 1 146 ? 1.12200   0.44900   17.71600 1.000 9.96351  ? 169 LEU A CA   1 
ATOM   2306 C  C    . LEU A 1 146 ? 1.20200   -0.30800  16.39300 1.000 10.37167 ? 169 LEU A C    1 
ATOM   2307 O  O    . LEU A 1 146 ? 1.78900   -1.38700  16.36700 1.000 10.66538 ? 169 LEU A O    1 
ATOM   2308 C  CB   . LEU A 1 146 ? 0.30300   -0.32500  18.76000 1.000 10.14662 ? 169 LEU A CB   1 
ATOM   2309 C  CG   . LEU A 1 146 ? -1.11500  -0.77500  18.41200 1.000 10.24211 ? 169 LEU A CG   1 
ATOM   2310 C  CD1  . LEU A 1 146 ? -1.12800  -2.15400  17.73400 1.000 12.35185 ? 169 LEU A CD1  1 
ATOM   2311 C  CD2  . LEU A 1 146 ? -1.96900  -0.84800  19.66800 1.000 10.51433 ? 169 LEU A CD2  1 
ATOM   2312 H  H    . LEU A 1 146 ? -0.14900  1.95900   17.92800 1.000 11.99241 ? 169 LEU A H    1 
ATOM   2313 H  HA   . LEU A 1 146 ? 2.02700   0.49100   18.06200 1.000 11.95427 ? 169 LEU A HA   1 
ATOM   2314 H  HB2  . LEU A 1 146 ? 0.79900   -1.12900  18.97900 1.000 12.17399 ? 169 LEU A HB2  1 
ATOM   2315 H  HB3  . LEU A 1 146 ? 0.22600   0.24100   19.54500 1.000 12.17399 ? 169 LEU A HB3  1 
ATOM   2316 H  HG   . LEU A 1 146 ? -1.48400  -0.12400  17.79500 1.000 12.28858 ? 169 LEU A HG   1 
ATOM   2317 H  HD11 . LEU A 1 146 ? -2.04700  -2.40800  17.55400 1.000 14.82027 ? 169 LEU A HD11 1 
ATOM   2318 H  HD12 . LEU A 1 146 ? -0.63100  -2.10200  16.90200 1.000 14.82027 ? 169 LEU A HD12 1 
ATOM   2319 H  HD13 . LEU A 1 146 ? -0.71500  -2.80100  18.32600 1.000 14.82027 ? 169 LEU A HD13 1 
ATOM   2320 H  HD21 . LEU A 1 146 ? -2.84200  -1.20000  19.43500 1.000 12.61525 ? 169 LEU A HD21 1 
ATOM   2321 H  HD22 . LEU A 1 146 ? -1.53700  -1.43300  20.31000 1.000 12.61525 ? 169 LEU A HD22 1 
ATOM   2322 H  HD23 . LEU A 1 146 ? -2.05900  0.04300   20.04000 1.000 12.61525 ? 169 LEU A HD23 1 
ATOM   2323 N  N    . ASN A 1 147 ? 0.69200   0.25900   15.30000 1.000 10.28154 ? 170 ASN A N    1 
ATOM   2324 C  CA   . ASN A 1 147 ? 0.65200   -0.40400  14.00100 1.000 10.67197 ? 170 ASN A CA   1 
ATOM   2325 C  C    . ASN A 1 147 ? 1.74200   0.03200   13.02800 1.000 11.15397 ? 170 ASN A C    1 
ATOM   2326 O  O    . ASN A 1 147 ? 1.66800   -0.32200  11.84900 1.000 12.12548 ? 170 ASN A O    1 
ATOM   2327 C  CB   . ASN A 1 147 ? -0.70300  -0.16400  13.34300 1.000 11.85721 ? 170 ASN A CB   1 
ATOM   2328 C  CG   . ASN A 1 147 ? -1.84900  -0.51000  14.26100 1.000 11.64522 ? 170 ASN A CG   1 
ATOM   2329 O  OD1  . ASN A 1 147 ? -2.09100  -1.69100  14.52900 1.000 12.34817 ? 170 ASN A OD1  1 
ATOM   2330 N  ND2  . ASN A 1 147 ? -2.55000  0.50400   14.76800 1.000 11.85122 ? 170 ASN A ND2  1 
ATOM   2331 H  H    . ASN A 1 147 ? 0.35400   1.05000   15.28800 1.000 12.33589 ? 170 ASN A H    1 
ATOM   2332 H  HA   . ASN A 1 147 ? 0.77900   -1.35100  14.16800 1.000 12.80441 ? 170 ASN A HA   1 
ATOM   2333 H  HB2  . ASN A 1 147 ? -0.78000  0.77200   13.10200 1.000 14.22671 ? 170 ASN A HB2  1 
ATOM   2334 H  HB3  . ASN A 1 147 ? -0.77400  -0.71700  12.54900 1.000 14.22671 ? 170 ASN A HB3  1 
ATOM   2335 H  HD21 . ASN A 1 147 ? -3.21100  0.34900   15.29600 1.000 14.21952 ? 170 ASN A HD21 1 
ATOM   2336 H  HD22 . ASN A 1 147 ? -2.34100  1.31400   14.56800 1.000 14.21952 ? 170 ASN A HD22 1 
ATOM   2337 N  N    . THR A 1 148 ? 2.75200   0.79000   13.45700 1.000 11.18517 ? 171 THR A N    1 
ATOM   2338 C  CA   . THR A 1 148 ? 3.74700   1.28000   12.50200 1.000 11.38962 ? 171 THR A CA   1 
ATOM   2339 C  C    . THR A 1 148 ? 4.48500   0.14400   11.79200 1.000 11.08074 ? 171 THR A C    1 
ATOM   2340 O  O    . THR A 1 148 ? 4.83600   0.28000   10.61300 1.000 11.55601 ? 171 THR A O    1 
ATOM   2341 C  CB   . THR A 1 148 ? 4.72100   2.23300   13.19300 1.000 12.18561 ? 171 THR A CB   1 
ATOM   2342 O  OG1  . THR A 1 148 ? 5.25300   1.66900   14.39500 1.000 11.86082 ? 171 THR A OG1  1 
ATOM   2343 C  CG2  . THR A 1 148 ? 4.05300   3.55100   13.54200 1.000 12.09956 ? 171 THR A CG2  1 
ATOM   2344 H  H    . THR A 1 148 ? 2.88100   1.03000   14.27300 1.000 13.42025 ? 171 THR A H    1 
ATOM   2345 H  HA   . THR A 1 148 ? 3.28300   1.78000   11.81300 1.000 13.66560 ? 171 THR A HA   1 
ATOM   2346 H  HB   . THR A 1 148 ? 5.44700   2.39700   12.57100 1.000 14.62078 ? 171 THR A HB   1 
ATOM   2347 H  HG1  . THR A 1 148 ? 5.84600   1.10400   14.20800 1.000 14.23104 ? 171 THR A HG1  1 
ATOM   2348 H  HG21 . THR A 1 148 ? 4.69900   4.15400   13.94300 1.000 14.51752 ? 171 THR A HG21 1 
ATOM   2349 H  HG22 . THR A 1 148 ? 3.69300   3.96300   12.74100 1.000 14.51752 ? 171 THR A HG22 1 
ATOM   2350 H  HG23 . THR A 1 148 ? 3.33000   3.40100   14.17100 1.000 14.51752 ? 171 THR A HG23 1 
ATOM   2351 N  N    . ALA A 1 149 ? 4.77700   -0.95400  12.50000 1.000 10.93954 ? 172 ALA A N    1 
ATOM   2352 C  CA   . ALA A 1 149 ? 5.30000   -2.19000  11.90800 1.000 11.09399 ? 172 ALA A CA   1 
ATOM   2353 C  C    . ALA A 1 149 ? 6.61300   -1.95400  11.14700 1.000 11.50587 ? 172 ALA A C    1 
ATOM   2354 O  O    . ALA A 1 149 ? 6.86200   -2.53600  10.08800 1.000 12.71337 ? 172 ALA A O    1 
ATOM   2355 C  CB   . ALA A 1 149 ? 4.24800   -2.88600  11.04900 1.000 11.65655 ? 172 ALA A CB   1 
ATOM   2356 H  H    . ALA A 1 149 ? 4.67800   -1.00900  13.35200 1.000 13.12550 ? 172 ALA A H    1 
ATOM   2357 H  HA   . ALA A 1 149 ? 5.52100   -2.79900  12.63000 1.000 13.31084 ? 172 ALA A HA   1 
ATOM   2358 H  HB1  . ALA A 1 149 ? 4.62100   -3.71100  10.70000 1.000 13.98592 ? 172 ALA A HB1  1 
ATOM   2359 H  HB2  . ALA A 1 149 ? 3.47100   -3.07900  11.59600 1.000 13.98592 ? 172 ALA A HB2  1 
ATOM   2360 H  HB3  . ALA A 1 149 ? 4.00000   -2.30000  10.31700 1.000 13.98592 ? 172 ALA A HB3  1 
ATOM   2361 N  N    . ILE A 1 150 ? 7.48900   -1.13900  11.71800 1.000 11.77321 ? 173 ILE A N    1 
ATOM   2362 C  CA   . ILE A 1 150 ? 8.77000   -0.81800  11.07300 1.000 12.78084 ? 173 ILE A CA   1 
ATOM   2363 C  C    . ILE A 1 150 ? 9.68300   -2.04300  11.11900 1.000 13.05481 ? 173 ILE A C    1 
ATOM   2364 O  O    . ILE A 1 150 ? 9.83600   -2.65900  12.18900 1.000 13.23148 ? 173 ILE A O    1 
ATOM   2365 C  CB   . ILE A 1 150 ? 9.41400   0.37200   11.77700 1.000 13.81068 ? 173 ILE A CB   1 
ATOM   2366 C  CG1  . ILE A 1 150 ? 8.50900   1.60200   11.67000 1.000 14.67741 ? 173 ILE A CG1  1 
ATOM   2367 C  CG2  . ILE A 1 150 ? 10.79400  0.63500   11.21200 1.000 15.66718 ? 173 ILE A CG2  1 
ATOM   2368 C  CD1  . ILE A 1 150 ? 8.82400   2.65900   12.70000 1.000 16.16036 ? 173 ILE A CD1  1 
ATOM   2369 H  H    . ILE A 1 150 ? 7.37300   -0.75500  12.47900 1.000 14.12590 ? 173 ILE A H    1 
ATOM   2370 H  HA   . ILE A 1 150 ? 8.62000   -0.59100  10.14200 1.000 15.33506 ? 173 ILE A HA   1 
ATOM   2371 H  HB   . ILE A 1 150 ? 9.51700   0.16400   12.71900 1.000 16.57087 ? 173 ILE A HB   1 
ATOM   2372 H  HG12 . ILE A 1 150 ? 8.61900   1.99800   10.79200 1.000 17.61094 ? 173 ILE A HG12 1 
ATOM   2373 H  HG13 . ILE A 1 150 ? 7.58700   1.32700   11.79700 1.000 17.61094 ? 173 ILE A HG13 1 
ATOM   2374 H  HG21 . ILE A 1 150 ? 11.15300  1.44000   11.61800 1.000 18.79866 ? 173 ILE A HG21 1 
ATOM   2375 H  HG22 . ILE A 1 150 ? 11.36700  -0.12100  11.41300 1.000 18.79866 ? 173 ILE A HG22 1 
ATOM   2376 H  HG23 . ILE A 1 150 ? 10.72400  0.75200   10.25100 1.000 18.79866 ? 173 ILE A HG23 1 
ATOM   2377 H  HD11 . ILE A 1 150 ? 8.24400   3.42300   12.55700 1.000 19.39048 ? 173 ILE A HD11 1 
ATOM   2378 H  HD12 . ILE A 1 150 ? 8.67400   2.29200   13.58600 1.000 19.39048 ? 173 ILE A HD12 1 
ATOM   2379 H  HD13 . ILE A 1 150 ? 9.75200   2.92600   12.60600 1.000 19.39048 ? 173 ILE A HD13 1 
ATOM   2380 N  N    . PRO A 1 151 ? 10.30900  -2.43900  10.01400 1.000 13.78902 ? 174 PRO A N    1 
ATOM   2381 C  CA   . PRO A 1 151 ? 11.20400  -3.60200  10.06200 1.000 14.67828 ? 174 PRO A CA   1 
ATOM   2382 C  C    . PRO A 1 151 ? 12.32300  -3.38600  11.07300 1.000 14.26005 ? 174 PRO A C    1 
ATOM   2383 O  O    . PRO A 1 151 ? 12.89700  -2.30000  11.17300 1.000 15.72543 ? 174 PRO A O    1 
ATOM   2384 C  CB   . PRO A 1 151 ? 11.73100  -3.70100  8.62300  1.000 16.65338 ? 174 PRO A CB   1 
ATOM   2385 C  CG   . PRO A 1 151 ? 10.64600  -3.07900  7.78700  1.000 17.03250 ? 174 PRO A CG   1 
ATOM   2386 C  CD   . PRO A 1 151 ? 10.09700  -1.95800  8.64000  1.000 14.95722 ? 174 PRO A CD   1 
ATOM   2387 H  HA   . PRO A 1 151 ? 10.72000  -4.41300  10.28200 1.000 17.61198 ? 174 PRO A HA   1 
ATOM   2388 H  HB2  . PRO A 1 151 ? 12.56200  -3.21000  8.53800  1.000 19.98211 ? 174 PRO A HB2  1 
ATOM   2389 H  HB3  . PRO A 1 151 ? 11.86800  -4.63100  8.38200  1.000 19.98211 ? 174 PRO A HB3  1 
ATOM   2390 H  HG2  . PRO A 1 151 ? 11.01900  -2.73600  6.96000  1.000 20.43705 ? 174 PRO A HG2  1 
ATOM   2391 H  HG3  . PRO A 1 151 ? 9.95900   -3.73600  7.59300  1.000 20.43705 ? 174 PRO A HG3  1 
ATOM   2392 H  HD2  . PRO A 1 151 ? 10.58600  -1.13400  8.48300  1.000 17.94671 ? 174 PRO A HD2  1 
ATOM   2393 H  HD3  . PRO A 1 151 ? 9.15300   -1.82100  8.46400  1.000 17.94671 ? 174 PRO A HD3  1 
ATOM   2394 N  N    . GLY A 1 152 ? 12.62000  -4.43400  11.83800 1.000 14.70106 ? 175 GLY A N    1 
ATOM   2395 C  CA   . GLY A 1 152 ? 13.63000  -4.38300  12.87200 1.000 14.92251 ? 175 GLY A CA   1 
ATOM   2396 C  C    . GLY A 1 152 ? 13.15200  -3.85700  14.21000 1.000 14.78720 ? 175 GLY A C    1 
ATOM   2397 O  O    . GLY A 1 152 ? 13.90900  -3.91700  15.18400 1.000 17.37098 ? 175 GLY A O    1 
ATOM   2398 H  H    . GLY A 1 152 ? 12.23800  -5.20100  11.77000 1.000 17.63932 ? 175 GLY A H    1 
ATOM   2399 H  HA2  . GLY A 1 152 ? 13.97400  -5.27900  13.01300 1.000 17.90507 ? 175 GLY A HA2  1 
ATOM   2400 H  HA3  . GLY A 1 152 ? 14.35300  -3.81100  12.57000 1.000 17.90507 ? 175 GLY A HA3  1 
ATOM   2401 N  N    . ASP A 1 153 ? 11.93000  -3.34400  14.28800 1.000 13.26003 ? 176 ASP A N    1 
ATOM   2402 C  CA   . ASP A 1 153 ? 11.42400  -2.72100  15.50800 1.000 13.23970 ? 176 ASP A CA   1 
ATOM   2403 C  C    . ASP A 1 153 ? 10.67900  -3.77000  16.32100 1.000 12.74337 ? 176 ASP A C    1 
ATOM   2404 O  O    . ASP A 1 153 ? 9.70100   -4.34500  15.82100 1.000 12.55688 ? 176 ASP A O    1 
ATOM   2405 C  CB   . ASP A 1 153 ? 10.48500  -1.58900  15.12200 1.000 13.00608 ? 176 ASP A CB   1 
ATOM   2406 C  CG   . ASP A 1 153 ? 10.03600  -0.73200  16.28600 1.000 12.97945 ? 176 ASP A CG   1 
ATOM   2407 O  OD1  . ASP A 1 153 ? 10.23900  -1.10600  17.46100 1.000 13.69198 ? 176 ASP A OD1  1 
ATOM   2408 O  OD2  . ASP A 1 153 ? 9.44200   0.33000   15.99800 1.000 14.62464 ? 176 ASP A OD2  1 
ATOM   2409 H  H    . ASP A 1 153 ? 11.36400  -3.34400  13.64000 1.000 15.91008 ? 176 ASP A H    1 
ATOM   2410 H  HA   . ASP A 1 153 ? 12.14400  -2.36900  16.05400 1.000 15.88569 ? 176 ASP A HA   1 
ATOM   2411 H  HB2  . ASP A 1 153 ? 10.93900  -1.01000  14.48900 1.000 15.60534 ? 176 ASP A HB2  1 
ATOM   2412 H  HB3  . ASP A 1 153 ? 9.69100   -1.96900  14.71300 1.000 15.60534 ? 176 ASP A HB3  1 
ATOM   2413 N  N    . PRO A 1 154 ? 11.11500  -4.07900  17.54800 1.000 12.90210 ? 177 PRO A N    1 
ATOM   2414 C  CA   . PRO A 1 154 ? 10.42200  -5.10900  18.33600 1.000 12.70265 ? 177 PRO A CA   1 
ATOM   2415 C  C    . PRO A 1 154 ? 9.16300   -4.61700  19.02800 1.000 11.68117 ? 177 PRO A C    1 
ATOM   2416 O  O    . PRO A 1 154 ? 8.46700   -5.42800  19.65200 1.000 11.36842 ? 177 PRO A O    1 
ATOM   2417 C  CB   . PRO A 1 154 ? 11.48500  -5.52200  19.36300 1.000 14.46877 ? 177 PRO A CB   1 
ATOM   2418 C  CG   . PRO A 1 154 ? 12.23100  -4.26100  19.60600 1.000 15.14234 ? 177 PRO A CG   1 
ATOM   2419 C  CD   . PRO A 1 154 ? 12.31900  -3.58600  18.24000 1.000 14.34336 ? 177 PRO A CD   1 
ATOM   2420 H  HA   . PRO A 1 154 ? 10.20200  -5.87100  17.77700 1.000 15.24123 ? 177 PRO A HA   1 
ATOM   2421 H  HB2  . PRO A 1 154 ? 11.06200  -5.84300  20.17500 1.000 17.36057 ? 177 PRO A HB2  1 
ATOM   2422 H  HB3  . PRO A 1 154 ? 12.06100  -6.20900  18.99500 1.000 17.36057 ? 177 PRO A HB3  1 
ATOM   2423 H  HG2  . PRO A 1 154 ? 11.74700  -3.70600  20.23600 1.000 18.16886 ? 177 PRO A HG2  1 
ATOM   2424 H  HG3  . PRO A 1 154 ? 13.11500  -4.46200  19.95100 1.000 18.16886 ? 177 PRO A HG3  1 
ATOM   2425 H  HD2  . PRO A 1 154 ? 12.29700  -2.62000  18.32900 1.000 17.21009 ? 177 PRO A HD2  1 
ATOM   2426 H  HD3  . PRO A 1 154 ? 13.12400  -3.85700  17.77100 1.000 17.21009 ? 177 PRO A HD3  1 
ATOM   2427 N  N    . ARG A 1 155 ? 8.85600   -3.32600  18.97200 1.000 11.20155 ? 178 ARG A N    1 
ATOM   2428 C  CA   . ARG A 1 155 ? 7.67500   -2.84200  19.67200 1.000 10.62953 ? 178 ARG A CA   1 
ATOM   2429 C  C    . ARG A 1 155 ? 6.41300   -3.50700  19.13300 1.000 10.38502 ? 178 ARG A C    1 
ATOM   2430 O  O    . ARG A 1 155 ? 6.22700   -3.65700  17.92400 1.000 10.60447 ? 178 ARG A O    1 
ATOM   2431 C  CB   . ARG A 1 155 ? 7.55500   -1.32800  19.55200 1.000 11.83193 ? 178 ARG A CB   1 
ATOM   2432 C  CG   . ARG A 1 155 ? 8.63500   -0.58900  20.27600 1.000 13.03031 ? 178 ARG A CG   1 
ATOM   2433 C  CD   . ARG A 1 155 ? 8.44500   0.90300   20.14700 1.000 13.37028 ? 178 ARG A CD   1 
ATOM   2434 N  NE   . ARG A 1 155 ? 8.70100   1.35300   18.78000 1.000 12.67197 ? 178 ARG A NE   1 
ATOM   2435 C  CZ   . ARG A 1 155 ? 8.53500   2.59600   18.35600 1.000 13.32114 ? 178 ARG A CZ   1 
ATOM   2436 N  NH1  . ARG A 1 155 ? 8.11400   3.55500   19.16600 1.000 13.86915 ? 178 ARG A NH1  1 
ATOM   2437 N  NH2  . ARG A 1 155 ? 8.79700   2.88100   17.08600 1.000 14.24077 ? 178 ARG A NH2  1 
ATOM   2438 H  H    . ARG A 1 155 ? 9.30300   -2.72700  18.54700 1.000 13.43991 ? 178 ARG A H    1 
ATOM   2439 H  HA   . ARG A 1 155 ? 7.76100   -3.06200  20.61200 1.000 12.75349 ? 178 ARG A HA   1 
ATOM   2440 H  HB2  . ARG A 1 155 ? 7.60300   -1.08200  18.61500 1.000 14.19636 ? 178 ARG A HB2  1 
ATOM   2441 H  HB3  . ARG A 1 155 ? 6.70300   -1.05000  19.92400 1.000 14.19636 ? 178 ARG A HB3  1 
ATOM   2442 H  HG2  . ARG A 1 155 ? 8.61100   -0.82100  21.21800 1.000 15.63442 ? 178 ARG A HG2  1 
ATOM   2443 H  HG3  . ARG A 1 155 ? 9.49700   -0.82300  19.89800 1.000 15.63442 ? 178 ARG A HG3  1 
ATOM   2444 H  HD2  . ARG A 1 155 ? 7.53100   1.13300   20.37900 1.000 16.04238 ? 178 ARG A HD2  1 
ATOM   2445 H  HD3  . ARG A 1 155 ? 9.06200   1.35900   20.74100 1.000 16.04238 ? 178 ARG A HD3  1 
ATOM   2446 H  HE   . ARG A 1 155 ? 8.98000   0.77100   18.21300 1.000 15.20441 ? 178 ARG A HE   1 
ATOM   2447 H  HH11 . ARG A 1 155 ? 7.94200   3.37800   19.99000 1.000 16.64103 ? 178 ARG A HH11 1 
ATOM   2448 H  HH12 . ARG A 1 155 ? 8.01300   4.35600   18.86800 1.000 16.64103 ? 178 ARG A HH12 1 
ATOM   2449 H  HH21 . ARG A 1 155 ? 9.07100   2.26300   16.55400 1.000 17.08697 ? 178 ARG A HH21 1 
ATOM   2450 H  HH22 . ARG A 1 155 ? 8.69400   3.68400   16.79600 1.000 17.08697 ? 178 ARG A HH22 1 
ATOM   2451 N  N    . ASP A 1 156 ? 5.50800   -3.88400  20.03800 1.000 9.83831  ? 179 ASP A N    1 
ATOM   2452 C  CA   . ASP A 1 156 ? 4.17200   -4.33600  19.64300 1.000 9.78778  ? 179 ASP A CA   1 
ATOM   2453 C  C    . ASP A 1 156 ? 4.24400   -5.58000  18.76300 1.000 9.57979  ? 179 ASP A C    1 
ATOM   2454 O  O    . ASP A 1 156 ? 3.47900   -5.73500  17.80700 1.000 9.90694  ? 179 ASP A O    1 
ATOM   2455 C  CB   . ASP A 1 156 ? 3.38900   -3.20800  18.97300 1.000 10.24679 ? 179 ASP A CB   1 
ATOM   2456 C  CG   . ASP A 1 156 ? 3.36500   -1.96400  19.83300 1.000 10.02124 ? 179 ASP A CG   1 
ATOM   2457 O  OD1  . ASP A 1 156 ? 2.75400   -2.03200  20.92300 1.000 10.16679 ? 179 ASP A OD1  1 
ATOM   2458 O  OD2  . ASP A 1 156 ? 4.00300   -0.95900  19.44400 1.000 11.03042 ? 179 ASP A OD2  1 
ATOM   2459 H  H    . ASP A 1 156 ? 5.64400   -3.88700  20.88700 1.000 11.80402 ? 179 ASP A H    1 
ATOM   2460 H  HA   . ASP A 1 156 ? 3.68200   -4.59300  20.44000 1.000 11.74338 ? 179 ASP A HA   1 
ATOM   2461 H  HB2  . ASP A 1 156 ? 3.80700   -2.98600  18.12700 1.000 12.29420 ? 179 ASP A HB2  1 
ATOM   2462 H  HB3  . ASP A 1 156 ? 2.47400   -3.49600  18.82700 1.000 12.29420 ? 179 ASP A HB3  1 
ATOM   2463 N  N    . THR A 1 157 ? 5.14700   -6.49300  19.11600 1.000 9.58991  ? 180 THR A N    1 
ATOM   2464 C  CA   . THR A 1 157 ? 5.36000   -7.71800  18.36900 1.000 9.74717  ? 180 THR A CA   1 
ATOM   2465 C  C    . THR A 1 157 ? 5.10300   -8.95600  19.21900 1.000 9.50492  ? 180 THR A C    1 
ATOM   2466 O  O    . THR A 1 157 ? 5.12300   -8.91600  20.45300 1.000 9.69911  ? 180 THR A O    1 
ATOM   2467 C  CB   . THR A 1 157 ? 6.79700   -7.83300  17.82300 1.000 9.66119  ? 180 THR A CB   1 
ATOM   2468 O  OG1  . THR A 1 157 ? 7.72200   -7.85800  18.91100 1.000 10.73230 ? 180 THR A OG1  1 
ATOM   2469 C  CG2  . THR A 1 157 ? 7.13400   -6.70200  16.85400 1.000 10.62216 ? 180 THR A CG2  1 
ATOM   2470 H  H    . THR A 1 157 ? 5.65900   -6.41800  19.80200 1.000 11.50594 ? 180 THR A H    1 
ATOM   2471 H  HA   . THR A 1 157 ? 4.72700   -7.70100  17.63400 1.000 11.69466 ? 180 THR A HA   1 
ATOM   2472 H  HB   . THR A 1 157 ? 6.87700   -8.65800  17.31900 1.000 11.59148 ? 180 THR A HB   1 
ATOM   2473 H  HG1  . THR A 1 157 ? 7.79400   -7.09000  19.24400 1.000 12.87681 ? 180 THR A HG1  1 
ATOM   2474 H  HG21 . THR A 1 157 ? 8.04000   -6.80700  16.52500 1.000 12.74464 ? 180 THR A HG21 1 
ATOM   2475 H  HG22 . THR A 1 157 ? 6.52200   -6.71700  16.10200 1.000 12.74464 ? 180 THR A HG22 1 
ATOM   2476 H  HG23 . THR A 1 157 ? 7.05900   -5.84600  17.30400 1.000 12.74464 ? 180 THR A HG23 1 
ATOM   2477 N  N    . THR A 1 158 ? 4.92500   -10.07200 18.52300 1.000 9.34658  ? 181 THR A N    1 
ATOM   2478 C  CA   . THR A 1 158 ? 5.04200   -11.39100 19.11900 1.000 9.29726  ? 181 THR A CA   1 
ATOM   2479 C  C    . THR A 1 158 ? 5.53000   -12.34300 18.03600 1.000 9.69795  ? 181 THR A C    1 
ATOM   2480 O  O    . THR A 1 158 ? 5.74900   -11.94200 16.88800 1.000 10.73723 ? 181 THR A O    1 
ATOM   2481 C  CB   . THR A 1 158 ? 3.74300   -11.83800 19.78400 1.000 10.07742 ? 181 THR A CB   1 
ATOM   2482 O  OG1  . THR A 1 158 ? 4.06700   -12.93700 20.63100 1.000 9.98996  ? 181 THR A OG1  1 
ATOM   2483 C  CG2  . THR A 1 158 ? 2.68400   -12.23500 18.76400 1.000 10.06200 ? 181 THR A CG2  1 
ATOM   2484 H  H    . THR A 1 158 ? 4.73100   -10.08900 17.68500 1.000 11.21394 ? 181 THR A H    1 
ATOM   2485 H  HA   . THR A 1 158 ? 5.70800   -11.37300 19.82400 1.000 11.15476 ? 181 THR A HA   1 
ATOM   2486 H  HB   . THR A 1 158 ? 3.35200   -11.11200 20.29500 1.000 12.09095 ? 181 THR A HB   1 
ATOM   2487 H  HG1  . THR A 1 158 ? 3.36400   -13.27400 20.94600 1.000 11.98601 ? 181 THR A HG1  1 
ATOM   2488 H  HG21 . THR A 1 158 ? 1.81600   -12.29600 19.19400 1.000 12.07246 ? 181 THR A HG21 1 
ATOM   2489 H  HG22 . THR A 1 158 ? 2.64000   -11.57200 18.05700 1.000 12.07246 ? 181 THR A HG22 1 
ATOM   2490 H  HG23 . THR A 1 158 ? 2.90400   -13.09600 18.37600 1.000 12.07246 ? 181 THR A HG23 1 
ATOM   2491 N  N    . SER A 1 159 ? 5.66600   -13.61500 18.39800 1.000 9.84108  ? 182 SER A N    1 
ATOM   2492 C  CA   . SER A 1 159 ? 6.02400   -14.64000 17.42700 1.000 9.94252  ? 182 SER A CA   1 
ATOM   2493 C  C    . SER A 1 159 ? 4.80400   -15.48900 17.10300 1.000 9.61765  ? 182 SER A C    1 
ATOM   2494 O  O    . SER A 1 159 ? 3.87600   -15.60600 17.91300 1.000 10.13362 ? 182 SER A O    1 
ATOM   2495 C  CB   . SER A 1 159 ? 7.13800   -15.55300 17.94700 1.000 10.14181 ? 182 SER A CB   1 
ATOM   2496 O  OG   . SER A 1 159 ? 6.63700   -16.38400 18.98300 1.000 10.35031 ? 182 SER A OG   1 
ATOM   2497 H  H    . SER A 1 159 ? 5.55500   -13.90600 19.20000 1.000 11.80735 ? 182 SER A H    1 
ATOM   2498 H  HA   . SER A 1 159 ? 6.35300   -14.21300 16.62000 1.000 11.92907 ? 182 SER A HA   1 
ATOM   2499 H  HB2  . SER A 1 159 ? 7.46200   -16.10800 17.22100 1.000 12.16822 ? 182 SER A HB2  1 
ATOM   2500 H  HB3  . SER A 1 159 ? 7.86100   -15.00800 18.29600 1.000 12.16822 ? 182 SER A HB3  1 
ATOM   2501 H  HG   . SER A 1 159 ? 7.25600   -16.85600 19.29800 1.000 12.41842 ? 182 SER A HG   1 
ATOM   2502 N  N    . PRO A 1 160 ? 4.77800   -16.12000 15.92000 1.000 9.74660  ? 183 PRO A N    1 
ATOM   2503 C  CA   . PRO A 1 160 ? 3.66300   -17.02500 15.61000 1.000 9.87328  ? 183 PRO A CA   1 
ATOM   2504 C  C    . PRO A 1 160 ? 3.51800   -18.14900 16.61700 1.000 9.09670  ? 183 PRO A C    1 
ATOM   2505 O  O    . PRO A 1 160 ? 2.38700   -18.46700 17.01200 1.000 9.89499  ? 183 PRO A O    1 
ATOM   2506 C  CB   . PRO A 1 160 ? 3.98600   -17.52400 14.19100 1.000 10.56867 ? 183 PRO A CB   1 
ATOM   2507 C  CG   . PRO A 1 160 ? 4.82300   -16.40800 13.59100 1.000 10.84003 ? 183 PRO A CG   1 
ATOM   2508 C  CD   . PRO A 1 160 ? 5.65200   -15.88900 14.74500 1.000 10.24084 ? 183 PRO A CD   1 
ATOM   2509 H  HA   . PRO A 1 160 ? 2.83000   -16.52900 15.57100 1.000 11.84599 ? 183 PRO A HA   1 
ATOM   2510 H  HB2  . PRO A 1 160 ? 4.48700   -18.35300 14.23400 1.000 12.68045 ? 183 PRO A HB2  1 
ATOM   2511 H  HB3  . PRO A 1 160 ? 3.16700   -17.65600 13.68800 1.000 12.68045 ? 183 PRO A HB3  1 
ATOM   2512 H  HG2  . PRO A 1 160 ? 5.39000   -16.75900 12.88700 1.000 13.00609 ? 183 PRO A HG2  1 
ATOM   2513 H  HG3  . PRO A 1 160 ? 4.24600   -15.71300 13.23800 1.000 13.00609 ? 183 PRO A HG3  1 
ATOM   2514 H  HD2  . PRO A 1 160 ? 6.48100   -16.38600 14.82700 1.000 12.28706 ? 183 PRO A HD2  1 
ATOM   2515 H  HD3  . PRO A 1 160 ? 5.84200   -14.94400 14.63700 1.000 12.28706 ? 183 PRO A HD3  1 
ATOM   2516 N  N    . ARG A 1 161 ? 4.62300   -18.75600 17.04300 1.000 9.85498  ? 184 ARG A N    1 
ATOM   2517 C  CA   . ARG A 1 161 ? 4.52700   -19.84500 18.01100 1.000 10.26839 ? 184 ARG A CA   1 
ATOM   2518 C  C    . ARG A 1 161 ? 3.87400   -19.37500 19.30400 1.000 9.64323  ? 184 ARG A C    1 
ATOM   2519 O  O    . ARG A 1 161 ? 2.95900   -20.02200 19.82800 1.000 10.68063 ? 184 ARG A O    1 
ATOM   2520 C  CB   . ARG A 1 161 ? 5.91000   -20.40800 18.31000 1.000 11.32477 ? 184 ARG A CB   1 
ATOM   2521 C  CG   . ARG A 1 161 ? 5.89100   -21.62900 19.24700 1.000 12.19526 ? 184 ARG A CG   1 
ATOM   2522 C  CD   . ARG A 1 161 ? 7.26600   -21.93400 19.85000 1.000 13.21233 ? 184 ARG A CD   1 
ATOM   2523 N  NE   . ARG A 1 161 ? 8.30900   -22.21300 18.86600 1.000 13.52691 ? 184 ARG A NE   1 
ATOM   2524 C  CZ   . ARG A 1 161 ? 8.70300   -23.42300 18.49300 1.000 13.92757 ? 184 ARG A CZ   1 
ATOM   2525 N  NH1  . ARG A 1 161 ? 8.07600   -24.51700 18.90000 1.000 15.52291 ? 184 ARG A NH1  1 
ATOM   2526 N  NH2  . ARG A 1 161 ? 9.74200   -23.53900 17.67100 1.000 14.82623 ? 184 ARG A NH2  1 
ATOM   2527 H  H    . ARG A 1 161 ? 5.42300   -18.56100 16.79300 1.000 11.82403 ? 184 ARG A H    1 
ATOM   2528 H  HA   . ARG A 1 161 ? 3.98200   -20.54900 17.62400 1.000 12.32012 ? 184 ARG A HA   1 
ATOM   2529 H  HB2  . ARG A 1 161 ? 6.32300   -20.68000 17.47600 1.000 13.58778 ? 184 ARG A HB2  1 
ATOM   2530 H  HB3  . ARG A 1 161 ? 6.44300   -19.71700 18.73400 1.000 13.58778 ? 184 ARG A HB3  1 
ATOM   2531 H  HG2  . ARG A 1 161 ? 5.27500   -21.45900 19.97700 1.000 14.63236 ? 184 ARG A HG2  1 
ATOM   2532 H  HG3  . ARG A 1 161 ? 5.60400   -22.40800 18.74600 1.000 14.63236 ? 184 ARG A HG3  1 
ATOM   2533 H  HD2  . ARG A 1 161 ? 7.55200   -21.16800 20.37100 1.000 15.85285 ? 184 ARG A HD2  1 
ATOM   2534 H  HD3  . ARG A 1 161 ? 7.18700   -22.71400 20.42200 1.000 15.85285 ? 184 ARG A HD3  1 
ATOM   2535 H  HE   . ARG A 1 161 ? 8.69800   -21.53900 18.50000 1.000 16.23034 ? 184 ARG A HE   1 
ATOM   2536 H  HH11 . ARG A 1 161 ? 7.39300   -24.45300 19.41900 1.000 18.62554 ? 184 ARG A HH11 1 
ATOM   2537 H  HH12 . ARG A 1 161 ? 8.35100   -25.29100 18.64400 1.000 18.62554 ? 184 ARG A HH12 1 
ATOM   2538 H  HH21 . ARG A 1 161 ? 10.14800  -22.83400 17.38900 1.000 17.78953 ? 184 ARG A HH21 1 
ATOM   2539 H  HH22 . ARG A 1 161 ? 10.00800  -24.31700 17.42100 1.000 17.78953 ? 184 ARG A HH22 1 
ATOM   2540 N  N    . ALA A 1 162 ? 4.33700   -18.24400 19.83600 1.000 10.17613 ? 185 ALA A N    1 
ATOM   2541 C  CA   . ALA A 1 162 ? 3.81000   -17.75600 21.10100 1.000 10.41442 ? 185 ALA A CA   1 
ATOM   2542 C  C    . ALA A 1 162 ? 2.34000   -17.41700 20.97900 1.000 10.13392 ? 185 ALA A C    1 
ATOM   2543 O  O    . ALA A 1 162 ? 1.54600   -17.76200 21.86000 1.000 10.08007 ? 185 ALA A O    1 
ATOM   2544 C  CB   . ALA A 1 162 ? 4.60300   -16.54500 21.58600 1.000 11.37461 ? 185 ALA A CB   1 
ATOM   2545 H  H    . ALA A 1 162 ? 4.94800   -17.75000 19.48700 1.000 12.20941 ? 185 ALA A H    1 
ATOM   2546 H  HA   . ALA A 1 162 ? 3.91100   -18.45400 21.76700 1.000 12.49536 ? 185 ALA A HA   1 
ATOM   2547 H  HB1  . ALA A 1 162 ? 4.20200   -16.21300 22.40500 1.000 13.64758 ? 185 ALA A HB1  1 
ATOM   2548 H  HB2  . ALA A 1 162 ? 5.52000   -16.81400 21.75200 1.000 13.64758 ? 185 ALA A HB2  1 
ATOM   2549 H  HB3  . ALA A 1 162 ? 4.57900   -15.85800 20.90300 1.000 13.64758 ? 185 ALA A HB3  1 
ATOM   2550 N  N    A MET A 1 163 ? 1.94800   -16.74200 19.89700 0.410 9.92489  ? 186 MET A N    1 
ATOM   2551 N  N    B MET A 1 163 ? 1.95000   -16.73600 19.90300 0.590 9.66944  ? 186 MET A N    1 
ATOM   2552 C  CA   A MET A 1 163 ? 0.55900   -16.32200 19.77400 0.410 9.74825  ? 186 MET A CA   1 
ATOM   2553 C  CA   B MET A 1 163 ? 0.55900   -16.33300 19.78300 0.590 9.58400  ? 186 MET A CA   1 
ATOM   2554 C  C    A MET A 1 163 ? -0.36700  -17.50500 19.52800 0.410 9.93440  ? 186 MET A C    1 
ATOM   2555 C  C    B MET A 1 163 ? -0.34500  -17.54000 19.59000 0.590 9.37457  ? 186 MET A C    1 
ATOM   2556 O  O    A MET A 1 163 ? -1.52700  -17.48000 19.95400 0.410 10.19463 ? 186 MET A O    1 
ATOM   2557 O  O    B MET A 1 163 ? -1.46200  -17.57400 20.11500 0.590 9.61614  ? 186 MET A O    1 
ATOM   2558 C  CB   A MET A 1 163 ? 0.40200   -15.25300 18.69000 0.410 10.05016 ? 186 MET A CB   1 
ATOM   2559 C  CB   B MET A 1 163 ? 0.37500   -15.29500 18.67700 0.590 10.89973 ? 186 MET A CB   1 
ATOM   2560 C  CG   A MET A 1 163 ? -0.97500  -14.61300 18.69700 0.410 9.80347  ? 186 MET A CG   1 
ATOM   2561 C  CG   B MET A 1 163 ? -0.97200  -14.60100 18.75100 0.590 11.53082 ? 186 MET A CG   1 
ATOM   2562 S  SD   A MET A 1 163 ? -1.34700  -13.69600 20.21900 0.410 9.87716  ? 186 MET A SD   1 
ATOM   2563 S  SD   B MET A 1 163 ? -1.20400  -13.62500 20.26600 0.590 12.70596 ? 186 MET A SD   1 
ATOM   2564 C  CE   A MET A 1 163 ? -1.23800  -12.00900 19.63500 0.410 11.04736 ? 186 MET A CE   1 
ATOM   2565 C  CE   B MET A 1 163 ? -2.50900  -14.54000 21.08800 0.590 12.28168 ? 186 MET A CE   1 
ATOM   2566 H  H    A MET A 1 163 ? 2.45500   -16.52200 19.23800 0.410 11.90792 ? 186 MET A H    1 
ATOM   2567 H  H    B MET A 1 163 ? 2.45700   -16.50400 19.24900 0.590 11.60138 ? 186 MET A H    1 
ATOM   2568 H  HA   A MET A 1 163 ? 0.29700   -15.90200 20.60800 0.410 11.69595 ? 186 MET A HA   1 
ATOM   2569 H  HA   B MET A 1 163 ? 0.30000   -15.88800 20.60500 0.590 11.49885 ? 186 MET A HA   1 
ATOM   2570 H  HB2  A MET A 1 163 ? 1.05900   -14.55500 18.83700 0.410 12.05824 ? 186 MET A HB2  1 
ATOM   2571 H  HB2  B MET A 1 163 ? 1.06700   -14.62000 18.75700 0.590 13.07772 ? 186 MET A HB2  1 
ATOM   2572 H  HB3  A MET A 1 163 ? 0.54000   -15.66100 17.82100 0.410 12.05824 ? 186 MET A HB3  1 
ATOM   2573 H  HB3  B MET A 1 163 ? 0.43900   -15.73600 17.81500 0.590 13.07772 ? 186 MET A HB3  1 
ATOM   2574 H  HG2  A MET A 1 163 ? -1.03400  -13.99100 17.95500 0.410 11.76222 ? 186 MET A HG2  1 
ATOM   2575 H  HG2  B MET A 1 163 ? -1.05600  -14.00000 17.99500 0.590 13.83503 ? 186 MET A HG2  1 
ATOM   2576 H  HG3  A MET A 1 163 ? -1.64400  -15.30900 18.60000 0.410 11.76222 ? 186 MET A HG3  1 
ATOM   2577 H  HG3  B MET A 1 163 ? -1.67100  -15.27200 18.72100 0.590 13.83503 ? 186 MET A HG3  1 
ATOM   2578 H  HE1  A MET A 1 163 ? -1.14400  -11.41600 20.39700 0.410 13.25489 ? 186 MET A HE1  1 
ATOM   2579 H  HE1  B MET A 1 163 ? -2.73600  -14.09000 21.91700 0.590 14.73607 ? 186 MET A HE1  1 
ATOM   2580 H  HE2  A MET A 1 163 ? -0.46600  -11.92500 19.05400 0.410 13.25489 ? 186 MET A HE2  1 
ATOM   2581 H  HE2  B MET A 1 163 ? -3.28500  -14.57500 20.50800 0.590 14.73607 ? 186 MET A HE2  1 
ATOM   2582 H  HE3  A MET A 1 163 ? -2.04600  -11.79200 19.14400 0.410 13.25489 ? 186 MET A HE3  1 
ATOM   2583 H  HE3  B MET A 1 163 ? -2.19500  -15.43800 21.27500 0.590 14.73607 ? 186 MET A HE3  1 
ATOM   2584 N  N    . ALA A 1 164 ? 0.11200   -18.54200 18.84100 1.000 9.42669  ? 187 ALA A N    1 
ATOM   2585 C  CA   . ALA A 1 164 ? -0.70400  -19.73700 18.66300 1.000 9.26394  ? 187 ALA A CA   1 
ATOM   2586 C  C    . ALA A 1 164 ? -0.89600  -20.44300 20.00300 1.000 9.28834  ? 187 ALA A C    1 
ATOM   2587 O  O    . ALA A 1 164 ? -2.00700  -20.86600 20.34600 1.000 9.74969  ? 187 ALA A O    1 
ATOM   2588 C  CB   . ALA A 1 164 ? -0.06700  -20.67700 17.63600 1.000 9.89170  ? 187 ALA A CB   1 
ATOM   2589 H  H    A ALA A 1 164 ? 0.88900   -18.57600 18.47500 0.410 11.31008 ? 187 ALA A H    1 
ATOM   2590 H  H    B ALA A 1 164 ? 0.87000   -18.55300 18.43600 0.590 11.31008 ? 187 ALA A H    1 
ATOM   2591 H  HA   . ALA A 1 164 ? -1.57400  -19.48300 18.31600 1.000 11.11478 ? 187 ALA A HA   1 
ATOM   2592 H  HB1  . ALA A 1 164 ? -0.62000  -21.46900 17.54800 1.000 11.86810 ? 187 ALA A HB1  1 
ATOM   2593 H  HB2  . ALA A 1 164 ? -0.00800  -20.21900 16.78300 1.000 11.86810 ? 187 ALA A HB2  1 
ATOM   2594 H  HB3  . ALA A 1 164 ? 0.81900   -20.92300 17.94200 1.000 11.86810 ? 187 ALA A HB3  1 
ATOM   2595 N  N    . GLN A 1 165 ? 0.19600   -20.61500 20.74900 1.000 9.42108  ? 188 GLN A N    1 
ATOM   2596 C  CA   . GLN A 1 165 ? 0.09800   -21.28400 22.04100 1.000 10.36165 ? 188 GLN A CA   1 
ATOM   2597 C  C    . GLN A 1 165 ? -0.80300  -20.49500 22.98400 1.000 9.95300  ? 188 GLN A C    1 
ATOM   2598 O  O    . GLN A 1 165 ? -1.63600  -21.07000 23.69200 1.000 10.34095 ? 188 GLN A O    1 
ATOM   2599 C  CB   . GLN A 1 165 ? 1.49600   -21.50000 22.61300 1.000 10.96942 ? 188 GLN A CB   1 
ATOM   2600 C  CG   . GLN A 1 165 ? 2.32100   -22.55600 21.86900 1.000 11.15366 ? 188 GLN A CG   1 
ATOM   2601 C  CD   . GLN A 1 165 ? 1.87900   -23.99500 22.12500 1.000 13.39635 ? 188 GLN A CD   1 
ATOM   2602 O  OE1  . GLN A 1 165 ? 1.02900   -24.27100 22.96200 1.000 14.29995 ? 188 GLN A OE1  1 
ATOM   2603 N  NE2  . GLN A 1 165 ? 2.46800   -24.92200 21.37900 1.000 17.06143 ? 188 GLN A NE2  1 
ATOM   2604 H  H    . GLN A 1 165 ? 0.98800   -20.35800 20.53400 1.000 11.30335 ? 188 GLN A H    1 
ATOM   2605 H  HA   . GLN A 1 165 ? -0.30000  -22.16200 21.93600 1.000 12.43203 ? 188 GLN A HA   1 
ATOM   2606 H  HB2  . GLN A 1 165 ? 1.98300   -20.66200 22.57000 1.000 13.16135 ? 188 GLN A HB2  1 
ATOM   2607 H  HB3  . GLN A 1 165 ? 1.41300   -21.78800 23.53600 1.000 13.16135 ? 188 GLN A HB3  1 
ATOM   2608 H  HG2  . GLN A 1 165 ? 2.24800   -22.39200 20.91600 1.000 13.38244 ? 188 GLN A HG2  1 
ATOM   2609 H  HG3  . GLN A 1 165 ? 3.24700   -22.48000 22.14900 1.000 13.38244 ? 188 GLN A HG3  1 
ATOM   2610 H  HE21 . GLN A 1 165 ? 3.05800   -24.69400 20.79700 1.000 20.47176 ? 188 GLN A HE21 1 
ATOM   2611 H  HE22 . GLN A 1 165 ? 2.25900   -25.75000 21.47900 1.000 20.47176 ? 188 GLN A HE22 1 
ATOM   2612 N  N    . THR A 1 166 ? -0.66400  -19.17300 22.98800 1.000 10.54256 ? 189 THR A N    1 
ATOM   2613 C  CA   . THR A 1 166 ? -1.51600  -18.37700 23.86300 1.000 9.90064  ? 189 THR A CA   1 
ATOM   2614 C  C    . THR A 1 166 ? -2.96700  -18.40400 23.41400 1.000 10.16771 ? 189 THR A C    1 
ATOM   2615 O  O    . THR A 1 166 ? -3.87700  -18.49400 24.25000 1.000 10.25639 ? 189 THR A O    1 
ATOM   2616 C  CB   . THR A 1 166 ? -0.98000  -16.95600 23.97000 1.000 11.13936 ? 189 THR A CB   1 
ATOM   2617 O  OG1  . THR A 1 166 ? 0.29700   -17.03400 24.59300 1.000 11.77122 ? 189 THR A OG1  1 
ATOM   2618 C  CG2  . THR A 1 166 ? -1.90300  -16.08400 24.79300 1.000 14.32759 ? 189 THR A CG2  1 
ATOM   2619 H  H    . THR A 1 166 ? -0.10400  -18.72800 22.51100 1.000 12.64912 ? 189 THR A H    1 
ATOM   2620 H  HA   . THR A 1 166 ? -1.49200  -18.75800 24.75400 1.000 11.87881 ? 189 THR A HA   1 
ATOM   2621 H  HB   . THR A 1 166 ? -0.91400  -16.54600 23.09400 1.000 13.36528 ? 189 THR A HB   1 
ATOM   2622 H  HG1  . THR A 1 166 ? 0.66900   -16.28100 24.58000 1.000 14.12351 ? 189 THR A HG1  1 
ATOM   2623 H  HG21 . THR A 1 166 ? -1.43700  -15.28200 25.07500 1.000 17.19116 ? 189 THR A HG21 1 
ATOM   2624 H  HG22 . THR A 1 166 ? -2.67700  -15.83000 24.26600 1.000 17.19116 ? 189 THR A HG22 1 
ATOM   2625 H  HG23 . THR A 1 166 ? -2.20200  -16.56700 25.57900 1.000 17.19116 ? 189 THR A HG23 1 
ATOM   2626 N  N    . LEU A 1 167 ? -3.21500  -18.31100 22.10300 1.000 10.64589 ? 190 LEU A N    1 
ATOM   2627 C  CA   . LEU A 1 167 ? -4.59800  -18.36400 21.64200 1.000 10.59388 ? 190 LEU A CA   1 
ATOM   2628 C  C    . LEU A 1 167 ? -5.21800  -19.71700 21.96800 1.000 10.44851 ? 190 LEU A C    1 
ATOM   2629 O  O    . LEU A 1 167 ? -6.39900  -19.79500 22.31300 1.000 11.17082 ? 190 LEU A O    1 
ATOM   2630 C  CB   . LEU A 1 167 ? -4.69200  -18.06300 20.14600 1.000 10.21306 ? 190 LEU A CB   1 
ATOM   2631 C  CG   . LEU A 1 167 ? -6.11400  -17.86000 19.61600 1.000 9.88785  ? 190 LEU A CG   1 
ATOM   2632 C  CD1  . LEU A 1 167 ? -6.76100  -16.64300 20.24900 1.000 11.37892 ? 190 LEU A CD1  1 
ATOM   2633 C  CD2  . LEU A 1 167 ? -6.12600  -17.74400 18.08400 1.000 10.64665 ? 190 LEU A CD2  1 
ATOM   2634 H  H    . LEU A 1 167 ? -2.62300  -18.22000 21.48700 1.000 12.77311 ? 190 LEU A H    1 
ATOM   2635 H  HA   . LEU A 1 167 ? -5.10600  -17.67400 22.09700 1.000 12.71071 ? 190 LEU A HA   1 
ATOM   2636 H  HB2  . LEU A 1 167 ? -4.19400  -17.25000 19.96500 1.000 12.25372 ? 190 LEU A HB2  1 
ATOM   2637 H  HB3  . LEU A 1 167 ? -4.30200  -18.80500 19.65800 1.000 12.25372 ? 190 LEU A HB3  1 
ATOM   2638 H  HG   . LEU A 1 167 ? -6.64100  -18.63800 19.85700 1.000 11.86347 ? 190 LEU A HG   1 
ATOM   2639 H  HD11 . LEU A 1 167 ? -7.63300  -16.50400 19.84700 1.000 13.65275 ? 190 LEU A HD11 1 
ATOM   2640 H  HD12 . LEU A 1 167 ? -6.85700  -16.79700 21.20200 1.000 13.65275 ? 190 LEU A HD12 1 
ATOM   2641 H  HD13 . LEU A 1 167 ? -6.19800  -15.86900 20.09400 1.000 13.65275 ? 190 LEU A HD13 1 
ATOM   2642 H  HD21 . LEU A 1 167 ? -7.04500  -17.71600 17.77700 1.000 12.77403 ? 190 LEU A HD21 1 
ATOM   2643 H  HD22 . LEU A 1 167 ? -5.66600  -16.93000 17.82500 1.000 12.77403 ? 190 LEU A HD22 1 
ATOM   2644 H  HD23 . LEU A 1 167 ? -5.67300  -18.51400 17.70600 1.000 12.77403 ? 190 LEU A HD23 1 
ATOM   2645 N  N    A ARG A 1 168 ? -4.43600  -20.79100 21.88300 0.475 10.42145 ? 191 ARG A N    1 
ATOM   2646 N  N    B ARG A 1 168 ? -4.43600  -20.80800 21.85700 0.525 10.67296 ? 191 ARG A N    1 
ATOM   2647 C  CA   A ARG A 1 168 ? -4.96200  -22.08200 22.29200 0.475 10.18377 ? 191 ARG A CA   1 
ATOM   2648 C  CA   B ARG A 1 168 ? -4.92700  -22.11000 22.30600 0.525 10.93367 ? 191 ARG A CA   1 
ATOM   2649 C  C    A ARG A 1 168 ? -5.37900  -22.05800 23.76000 0.475 9.51764  ? 191 ARG A C    1 
ATOM   2650 C  C    B ARG A 1 168 ? -5.39300  -22.02400 23.75400 0.525 10.70940 ? 191 ARG A C    1 
ATOM   2651 O  O    A ARG A 1 168 ? -6.45100  -22.55500 24.12300 0.475 9.48734  ? 191 ARG A O    1 
ATOM   2652 O  O    B ARG A 1 168 ? -6.50400  -22.43800 24.09600 0.525 11.16519 ? 191 ARG A O    1 
ATOM   2653 C  CB   A ARG A 1 168 ? -3.93000  -23.17000 22.03700 0.475 10.52671 ? 191 ARG A CB   1 
ATOM   2654 C  CB   B ARG A 1 168 ? -3.85600  -23.20800 22.17600 0.525 11.94794 ? 191 ARG A CB   1 
ATOM   2655 C  CG   A ARG A 1 168 ? -4.49700  -24.52900 22.30400 0.475 11.54903 ? 191 ARG A CG   1 
ATOM   2656 C  CG   B ARG A 1 168 ? -4.35100  -24.59300 22.70900 0.525 13.10703 ? 191 ARG A CG   1 
ATOM   2657 C  CD   A ARG A 1 168 ? -4.09200  -24.98600 23.68800 0.475 11.76764 ? 191 ARG A CD   1 
ATOM   2658 C  CD   B ARG A 1 168 ? -3.36400  -25.77300 22.55700 0.525 13.23352 ? 191 ARG A CD   1 
ATOM   2659 N  NE   A ARG A 1 168 ? -2.67400  -25.31100 23.69600 0.475 12.82981 ? 191 ARG A NE   1 
ATOM   2660 N  NE   B ARG A 1 168 ? -4.02600  -27.04900 22.80500 0.525 14.33023 ? 191 ARG A NE   1 
ATOM   2661 C  CZ   A ARG A 1 168 ? -2.16600  -26.40800 23.15000 0.475 13.02291 ? 191 ARG A CZ   1 
ATOM   2662 C  CZ   B ARG A 1 168 ? -3.51200  -28.23600 22.51100 0.525 13.73215 ? 191 ARG A CZ   1 
ATOM   2663 N  NH1  A ARG A 1 168 ? -2.94000  -27.39100 22.72300 0.475 13.08918 ? 191 ARG A NH1  1 
ATOM   2664 N  NH1  B ARG A 1 168 ? -2.27400  -28.35800 22.05200 0.525 11.54093 ? 191 ARG A NH1  1 
ATOM   2665 N  NH2  A ARG A 1 168 ? -0.84500  -26.53500 23.05500 0.475 14.58526 ? 191 ARG A NH2  1 
ATOM   2666 N  NH2  B ARG A 1 168 ? -4.26900  -29.32300 22.65400 0.525 13.66535 ? 191 ARG A NH2  1 
ATOM   2667 H  H    A ARG A 1 168 ? -3.62300  -20.79600 21.60100 0.475 12.50379 ? 191 ARG A H    1 
ATOM   2668 H  H    B ARG A 1 168 ? -3.64000  -20.81300 21.53400 0.525 12.80560 ? 191 ARG A H    1 
ATOM   2669 H  HA   A ARG A 1 168 ? -5.74700  -22.29100 21.76100 0.475 12.21858 ? 191 ARG A HA   1 
ATOM   2670 H  HA   B ARG A 1 168 ? -5.66400  -22.36300 21.72800 0.525 13.11846 ? 191 ARG A HA   1 
ATOM   2671 H  HB2  A ARG A 1 168 ? -3.64700  -23.13200 21.11000 0.475 12.63011 ? 191 ARG A HB2  1 
ATOM   2672 H  HB2  B ARG A 1 168 ? -3.62100  -23.31200 21.24100 0.525 14.33558 ? 191 ARG A HB2  1 
ATOM   2673 H  HB3  A ARG A 1 168 ? -3.16900  -23.03400 22.62200 0.475 12.63011 ? 191 ARG A HB3  1 
ATOM   2674 H  HB3  B ARG A 1 168 ? -3.07400  -22.94900 22.68800 0.525 14.33558 ? 191 ARG A HB3  1 
ATOM   2675 H  HG2  A ARG A 1 168 ? -5.46500  -24.49700 22.25600 0.475 13.85689 ? 191 ARG A HG2  1 
ATOM   2676 H  HG2  B ARG A 1 168 ? -4.54300  -24.50200 23.65600 0.525 15.72649 ? 191 ARG A HG2  1 
ATOM   2677 H  HG3  A ARG A 1 168 ? -4.15400  -25.16200 21.65300 0.475 13.85689 ? 191 ARG A HG3  1 
ATOM   2678 H  HG3  B ARG A 1 168 ? -5.15900  -24.83200 22.22800 0.525 15.72649 ? 191 ARG A HG3  1 
ATOM   2679 H  HD2  A ARG A 1 168 ? -4.25500  -24.27700 24.32900 0.475 14.11922 ? 191 ARG A HD2  1 
ATOM   2680 H  HD2  B ARG A 1 168 ? -3.01000  -25.78200 21.65400 0.525 15.87828 ? 191 ARG A HD2  1 
ATOM   2681 H  HD3  A ARG A 1 168 ? -4.59700  -25.77700 23.93400 0.475 14.11922 ? 191 ARG A HD3  1 
ATOM   2682 H  HD3  B ARG A 1 168 ? -2.64200  -25.67300 23.19600 0.525 15.87828 ? 191 ARG A HD3  1 
ATOM   2683 H  HE   A ARG A 1 168 ? -2.13500  -24.76000 24.07600 0.475 15.39383 ? 191 ARG A HE   1 
ATOM   2684 H  HE   B ARG A 1 168 ? -4.80600  -27.03100 23.16800 0.525 17.19433 ? 191 ARG A HE   1 
ATOM   2685 H  HH11 A ARG A 1 168 ? -3.79400  -27.32800 22.79500 0.475 15.70506 ? 191 ARG A HH11 1 
ATOM   2686 H  HH11 B ARG A 1 168 ? -1.78600  -27.65900 21.93900 0.525 13.84716 ? 191 ARG A HH11 1 
ATOM   2687 H  HH12 A ARG A 1 168 ? -2.58900  -28.09400 22.37200 0.475 15.70506 ? 191 ARG A HH12 1 
ATOM   2688 H  HH12 B ARG A 1 168 ? -1.95900  -29.13700 21.86700 0.525 13.84716 ? 191 ARG A HH12 1 
ATOM   2689 H  HH21 A ARG A 1 168 ? -0.33100  -25.91000 23.34600 0.475 17.50036 ? 191 ARG A HH21 1 
ATOM   2690 H  HH21 B ARG A 1 168 ? -5.07900  -29.25000 22.93400 0.525 16.39647 ? 191 ARG A HH21 1 
ATOM   2691 H  HH22 A ARG A 1 168 ? -0.50500  -27.24300 22.70300 0.475 17.50036 ? 191 ARG A HH22 1 
ATOM   2692 H  HH22 B ARG A 1 168 ? -3.94800  -30.09900 22.46700 0.525 16.39647 ? 191 ARG A HH22 1 
ATOM   2693 N  N    . ASN A 1 169 ? -4.53800  -21.48500 24.61900 1.000 9.87494  ? 192 ASN A N    1 
ATOM   2694 C  CA   . ASN A 1 169 ? -4.86300  -21.38800 26.03800 1.000 9.91944  ? 192 ASN A CA   1 
ATOM   2695 C  C    . ASN A 1 169 ? -6.14100  -20.58200 26.25700 1.000 10.25500 ? 192 ASN A C    1 
ATOM   2696 O  O    . ASN A 1 169 ? -7.02500  -20.98400 27.02500 1.000 10.90361 ? 192 ASN A O    1 
ATOM   2697 C  CB   . ASN A 1 169 ? -3.66000  -20.76500 26.74700 1.000 9.95809  ? 192 ASN A CB   1 
ATOM   2698 C  CG   . ASN A 1 169 ? -3.74700  -20.85600 28.23700 1.000 10.59986 ? 192 ASN A CG   1 
ATOM   2699 O  OD1  . ASN A 1 169 ? -4.56600  -21.58800 28.80300 1.000 11.65659 ? 192 ASN A OD1  1 
ATOM   2700 N  ND2  . ASN A 1 169 ? -2.89300  -20.09000 28.90100 1.000 12.67290 ? 192 ASN A ND2  1 
ATOM   2701 H  H    A ASN A 1 169 ? -3.77600  -21.14700 24.40600 0.475 11.84798 ? 192 ASN A H    1 
ATOM   2702 H  H    B ASN A 1 169 ? -3.76500  -21.16900 24.41100 0.525 11.84798 ? 192 ASN A H    1 
ATOM   2703 H  HA   . ASN A 1 169 ? -5.02900  -22.26600 26.41500 1.000 11.90138 ? 192 ASN A HA   1 
ATOM   2704 H  HB2  . ASN A 1 169 ? -2.85500  -21.22700 26.46600 1.000 11.94776 ? 192 ASN A HB2  1 
ATOM   2705 H  HB3  . ASN A 1 169 ? -3.60400  -19.82600 26.50800 1.000 11.94776 ? 192 ASN A HB3  1 
ATOM   2706 H  HD21 . ASN A 1 169 ? -2.89000  -20.09400 29.76100 1.000 15.20553 ? 192 ASN A HD21 1 
ATOM   2707 H  HD22 . ASN A 1 169 ? -2.34200  -19.58800 28.47100 1.000 15.20553 ? 192 ASN A HD22 1 
ATOM   2708 N  N    . LEU A 1 170 ? -6.26200  -19.44400 25.57200 1.000 9.76048  ? 193 LEU A N    1 
ATOM   2709 C  CA   . LEU A 1 170 ? -7.40200  -18.55500 25.75500 1.000 9.88898  ? 193 LEU A CA   1 
ATOM   2710 C  C    . LEU A 1 170 ? -8.71500  -19.15700 25.26700 1.000 9.90925  ? 193 LEU A C    1 
ATOM   2711 O  O    . LEU A 1 170 ? -9.75700  -18.94200 25.89900 1.000 11.21952 ? 193 LEU A O    1 
ATOM   2712 C  CB   . LEU A 1 170 ? -7.15100  -17.25000 25.01600 1.000 10.66493 ? 193 LEU A CB   1 
ATOM   2713 C  CG   . LEU A 1 170 ? -6.06400  -16.33200 25.57100 1.000 10.58753 ? 193 LEU A CG   1 
ATOM   2714 C  CD1  . LEU A 1 170 ? -5.81000  -15.18100 24.61900 1.000 12.27261 ? 193 LEU A CD1  1 
ATOM   2715 C  CD2  . LEU A 1 170 ? -6.48200  -15.80200 26.94400 1.000 11.50985 ? 193 LEU A CD2  1 
ATOM   2716 H  H    . LEU A 1 170 ? -5.69300  -19.16300 24.99200 1.000 11.71063 ? 193 LEU A H    1 
ATOM   2717 H  HA   . LEU A 1 170 ? -7.49100  -18.38900 26.70700 1.000 11.86482 ? 193 LEU A HA   1 
ATOM   2718 H  HB2  . LEU A 1 170 ? -6.89800  -17.46800 24.10500 1.000 12.79597 ? 193 LEU A HB2  1 
ATOM   2719 H  HB3  . LEU A 1 170 ? -7.97800  -16.74300 25.01800 1.000 12.79597 ? 193 LEU A HB3  1 
ATOM   2720 H  HG   . LEU A 1 170 ? -5.23800  -16.83100 25.67000 1.000 12.70309 ? 193 LEU A HG   1 
ATOM   2721 H  HD11 . LEU A 1 170 ? -5.15200  -14.58600 25.01200 1.000 14.72519 ? 193 LEU A HD11 1 
ATOM   2722 H  HD12 . LEU A 1 170 ? -5.47800  -15.53400 23.77900 1.000 14.72519 ? 193 LEU A HD12 1 
ATOM   2723 H  HD13 . LEU A 1 170 ? -6.64100  -14.70400 24.47200 1.000 14.72519 ? 193 LEU A HD13 1 
ATOM   2724 H  HD21 . LEU A 1 170 ? -5.81300  -15.17300 27.25700 1.000 13.80987 ? 193 LEU A HD21 1 
ATOM   2725 H  HD22 . LEU A 1 170 ? -7.34100  -15.35900 26.86300 1.000 13.80987 ? 193 LEU A HD22 1 
ATOM   2726 H  HD23 . LEU A 1 170 ? -6.55100  -16.54700 27.56200 1.000 13.80987 ? 193 LEU A HD23 1 
ATOM   2727 N  N    . THR A 1 171 ? -8.70200  -19.84700 24.11700 1.000 10.29159 ? 194 THR A N    1 
ATOM   2728 C  CA   . THR A 1 171 ? -9.94600  -20.27600 23.48500 1.000 10.80187 ? 194 THR A CA   1 
ATOM   2729 C  C    . THR A 1 171 ? -10.29300 -21.73400 23.73700 1.000 11.11578 ? 194 THR A C    1 
ATOM   2730 O  O    . THR A 1 171 ? -11.47900 -22.07200 23.72200 1.000 13.30792 ? 194 THR A O    1 
ATOM   2731 C  CB   . THR A 1 171 ? -9.91900  -20.03800 21.96300 1.000 10.67432 ? 194 THR A CB   1 
ATOM   2732 O  OG1  . THR A 1 171 ? -8.85200  -20.78900 21.36200 1.000 11.57255 ? 194 THR A OG1  1 
ATOM   2733 C  CG2  . THR A 1 171 ? -9.77300  -18.56800 21.63800 1.000 11.64222 ? 194 THR A CG2  1 
ATOM   2734 H  H    . THR A 1 171 ? -7.99000  -20.07400 23.69200 1.000 12.34796 ? 194 THR A H    1 
ATOM   2735 H  HA   . THR A 1 171 ? -10.65600 -19.72800 23.85300 1.000 12.96030 ? 194 THR A HA   1 
ATOM   2736 H  HB   . THR A 1 171 ? -10.76100 -20.33700 21.58400 1.000 12.80723 ? 194 THR A HB   1 
ATOM   2737 H  HG1  . THR A 1 171 ? -8.11700  -20.56400 21.70100 1.000 13.88511 ? 194 THR A HG1  1 
ATOM   2738 H  HG21 . THR A 1 171 ? -9.73700  -18.44200 20.67700 1.000 13.96872 ? 194 THR A HG21 1 
ATOM   2739 H  HG22 . THR A 1 171 ? -10.52800 -18.07300 21.99200 1.000 13.96872 ? 194 THR A HG22 1 
ATOM   2740 H  HG23 . THR A 1 171 ? -8.95700  -18.22100 22.03100 1.000 13.96872 ? 194 THR A HG23 1 
ATOM   2741 N  N    . LEU A 1 172 ? -9.30600  -22.60700 23.92800 1.000 10.51425 ? 195 LEU A N    1 
ATOM   2742 C  CA   . LEU A 1 172 ? -9.52500  -24.03000 24.13900 1.000 11.18109 ? 195 LEU A CA   1 
ATOM   2743 C  C    . LEU A 1 172 ? -9.03800  -24.50600 25.49100 1.000 12.19858 ? 195 LEU A C    1 
ATOM   2744 O  O    . LEU A 1 172 ? -9.50800  -25.54500 25.97100 1.000 15.55874 ? 195 LEU A O    1 
ATOM   2745 C  CB   . LEU A 1 172 ? -8.77700  -24.82700 23.05900 1.000 11.61455 ? 195 LEU A CB   1 
ATOM   2746 C  CG   . LEU A 1 172 ? -9.15400  -24.48600 21.61700 1.000 11.84559 ? 195 LEU A CG   1 
ATOM   2747 C  CD1  . LEU A 1 172 ? -8.26100  -25.28300 20.67400 1.000 13.49051 ? 195 LEU A CD1  1 
ATOM   2748 C  CD2  . LEU A 1 172 ? -10.61600 -24.77200 21.33800 1.000 13.33796 ? 195 LEU A CD2  1 
ATOM   2749 H  H    . LEU A 1 172 ? -8.47400  -22.39000 23.94000 1.000 12.61515 ? 195 LEU A H    1 
ATOM   2750 H  HA   . LEU A 1 172 ? -10.47200 -24.22800 24.06700 1.000 13.41536 ? 195 LEU A HA   1 
ATOM   2751 H  HB2  . LEU A 1 172 ? -7.82700  -24.65900 23.15900 1.000 13.93551 ? 195 LEU A HB2  1 
ATOM   2752 H  HB3  . LEU A 1 172 ? -8.96200  -25.77000 23.19300 1.000 13.93551 ? 195 LEU A HB3  1 
ATOM   2753 H  HG   . LEU A 1 172 ? -9.02200  -23.53700 21.46600 1.000 14.21276 ? 195 LEU A HG   1 
ATOM   2754 H  HD11 . LEU A 1 172 ? -8.50800  -25.08000 19.75900 1.000 16.18666 ? 195 LEU A HD11 1 
ATOM   2755 H  HD12 . LEU A 1 172 ? -7.33700  -25.03600 20.83000 1.000 16.18666 ? 195 LEU A HD12 1 
ATOM   2756 H  HD13 . LEU A 1 172 ? -8.38400  -26.23000 20.84700 1.000 16.18666 ? 195 LEU A HD13 1 
ATOM   2757 H  HD21 . LEU A 1 172 ? -10.78600 -24.65200 20.39100 1.000 16.00360 ? 195 LEU A HD21 1 
ATOM   2758 H  HD22 . LEU A 1 172 ? -10.81500 -25.68500 21.59700 1.000 16.00360 ? 195 LEU A HD22 1 
ATOM   2759 H  HD23 . LEU A 1 172 ? -11.16200 -24.15600 21.85300 1.000 16.00360 ? 195 LEU A HD23 1 
ATOM   2760 N  N    . GLY A 1 173 ? -8.12100  -23.78600 26.11300 1.000 11.13803 ? 196 GLY A N    1 
ATOM   2761 C  CA   . GLY A 1 173 ? -7.58400  -24.11100 27.41000 1.000 10.70870 ? 196 GLY A CA   1 
ATOM   2762 C  C    . GLY A 1 173 ? -8.27500  -23.35800 28.51900 1.000 11.16066 ? 196 GLY A C    1 
ATOM   2763 O  O    . GLY A 1 173 ? -9.43900  -22.96400 28.40600 1.000 12.40586 ? 196 GLY A O    1 
ATOM   2764 H  H    . GLY A 1 173 ? -7.78100  -23.06900 25.78300 1.000 13.36369 ? 196 GLY A H    1 
ATOM   2765 H  HA2  . GLY A 1 173 ? -7.69000  -25.06100 27.57300 1.000 12.84849 ? 196 GLY A HA2  1 
ATOM   2766 H  HA3  . GLY A 1 173 ? -6.64000  -23.89000 27.43200 1.000 12.84849 ? 196 GLY A HA3  1 
ATOM   2767 N  N    . LYS A 1 174 ? -7.55000  -23.17600 29.62000 1.000 12.24869 ? 197 LYS A N    1 
ATOM   2768 C  CA   . LYS A 1 174 ? -8.12600  -22.77600 30.89900 1.000 12.86460 ? 197 LYS A CA   1 
ATOM   2769 C  C    . LYS A 1 174 ? -7.59400  -21.43100 31.37900 1.000 12.46986 ? 197 LYS A C    1 
ATOM   2770 O  O    . LYS A 1 174 ? -7.67700  -21.12400 32.57000 1.000 13.27240 ? 197 LYS A O    1 
ATOM   2771 C  CB   . LYS A 1 174 ? -7.88000  -23.88800 31.92500 1.000 15.18274 ? 197 LYS A CB   1 
ATOM   2772 C  CG   . LYS A 1 174 ? -8.52900  -25.21500 31.49800 1.000 15.79326 ? 197 LYS A CG   1 
ATOM   2773 C  CD   . LYS A 1 174 ? -7.90000  -26.41400 32.20800 1.000 18.34584 ? 197 LYS A CD   1 
ATOM   2774 C  CE   . LYS A 1 174 ? -8.57200  -27.71700 31.82500 1.000 19.01334 ? 197 LYS A CE   1 
ATOM   2775 N  NZ   . LYS A 1 174 ? -8.57000  -27.93900 30.35000 1.000 20.34599 ? 197 LYS A NZ   1 
ATOM   2776 H  H    . LYS A 1 174 ? -6.69700  -23.28200 29.65200 1.000 14.69648 ? 197 LYS A H    1 
ATOM   2777 H  HA   . LYS A 1 174 ? -9.08400  -22.65900 30.80600 1.000 15.43557 ? 197 LYS A HA   1 
ATOM   2778 H  HB2  . LYS A 1 174 ? -6.92500  -24.03300 32.01600 1.000 18.21733 ? 197 LYS A HB2  1 
ATOM   2779 H  HB3  . LYS A 1 174 ? -8.25900  -23.62500 32.77800 1.000 18.21733 ? 197 LYS A HB3  1 
ATOM   2780 H  HG2  . LYS A 1 174 ? -9.47300  -25.19400 31.71800 1.000 18.94996 ? 197 LYS A HG2  1 
ATOM   2781 H  HG3  . LYS A 1 174 ? -8.41300  -25.33400 30.54200 1.000 18.94996 ? 197 LYS A HG3  1 
ATOM   2782 H  HD2  . LYS A 1 174 ? -6.96300  -26.47300 31.96500 1.000 22.01306 ? 197 LYS A HD2  1 
ATOM   2783 H  HD3  . LYS A 1 174 ? -7.98700  -26.29800 33.16700 1.000 22.01306 ? 197 LYS A HD3  1 
ATOM   2784 H  HE2  . LYS A 1 174 ? -8.10000  -28.45400 32.24200 1.000 22.81406 ? 197 LYS A HE2  1 
ATOM   2785 H  HE3  . LYS A 1 174 ? -9.49400  -27.70000 32.12600 1.000 22.81406 ? 197 LYS A HE3  1 
ATOM   2786 H  HZ1  . LYS A 1 174 ? -7.75800  -27.78300 30.02000 1.000 24.41323 ? 197 LYS A HZ1  1 
ATOM   2787 H  HZ2  . LYS A 1 174 ? -8.79900  -28.78000 30.16900 1.000 24.41323 ? 197 LYS A HZ2  1 
ATOM   2788 H  HZ3  . LYS A 1 174 ? -9.15100  -27.39000 29.95900 1.000 24.41323 ? 197 LYS A HZ3  1 
ATOM   2789 N  N    . ALA A 1 175 ? -7.06800  -20.60500 30.47900 1.000 11.73342 ? 198 ALA A N    1 
ATOM   2790 C  CA   . ALA A 1 175 ? -6.61400  -19.27600 30.88100 1.000 11.63723 ? 198 ALA A CA   1 
ATOM   2791 C  C    . ALA A 1 175 ? -7.73500  -18.47800 31.52900 1.000 11.51841 ? 198 ALA A C    1 
ATOM   2792 O  O    . ALA A 1 175 ? -7.50400  -17.71700 32.47900 1.000 13.28696 ? 198 ALA A O    1 
ATOM   2793 C  CB   . ALA A 1 175 ? -6.08200  -18.52600 29.66800 1.000 11.25286 ? 198 ALA A CB   1 
ATOM   2794 H  H    . ALA A 1 175 ? -6.96400  -20.78500 29.64400 1.000 14.07815 ? 198 ALA A H    1 
ATOM   2795 H  HA   . ALA A 1 175 ? -5.89800  -19.37700 31.52700 1.000 13.96272 ? 198 ALA A HA   1 
ATOM   2796 H  HB1  . ALA A 1 175 ? -5.78700  -17.64500 29.94600 1.000 13.50149 ? 198 ALA A HB1  1 
ATOM   2797 H  HB2  . ALA A 1 175 ? -5.33600  -19.02100 29.29300 1.000 13.50149 ? 198 ALA A HB2  1 
ATOM   2798 H  HB3  . ALA A 1 175 ? -6.79000  -18.44600 29.01000 1.000 13.50149 ? 198 ALA A HB3  1 
ATOM   2799 N  N    . LEU A 1 176 ? -8.93700  -18.59800 30.99300 1.000 10.94718 ? 199 LEU A N    1 
ATOM   2800 C  CA   . LEU A 1 176 ? -10.10400 -17.85000 31.43100 1.000 11.63880 ? 199 LEU A CA   1 
ATOM   2801 C  C    . LEU A 1 176 ? -11.12300 -18.81500 32.02800 1.000 12.44816 ? 199 LEU A C    1 
ATOM   2802 O  O    . LEU A 1 176 ? -11.15600 -19.99800 31.67900 1.000 13.28461 ? 199 LEU A O    1 
ATOM   2803 C  CB   . LEU A 1 176 ? -10.73700 -17.14100 30.23300 1.000 10.77277 ? 199 LEU A CB   1 
ATOM   2804 C  CG   . LEU A 1 176 ? -9.86700  -16.08800 29.54200 1.000 11.83814 ? 199 LEU A CG   1 
ATOM   2805 C  CD1  . LEU A 1 176 ? -10.55800 -15.57300 28.27900 1.000 12.11843 ? 199 LEU A CD1  1 
ATOM   2806 C  CD2  . LEU A 1 176 ? -9.56500  -14.93500 30.49400 1.000 13.61569 ? 199 LEU A CD2  1 
ATOM   2807 H  H    . LEU A 1 176 ? -9.11100  -19.13300 30.34200 1.000 13.13467 ? 199 LEU A H    1 
ATOM   2808 H  HA   . LEU A 1 176 ? -9.85800  -17.19400 32.10200 1.000 13.96462 ? 199 LEU A HA   1 
ATOM   2809 H  HB2  . LEU A 1 176 ? -10.96100 -17.81200 29.56900 1.000 12.92538 ? 199 LEU A HB2  1 
ATOM   2810 H  HB3  . LEU A 1 176 ? -11.54300 -16.69500 30.53700 1.000 12.92538 ? 199 LEU A HB3  1 
ATOM   2811 H  HG   . LEU A 1 176 ? -9.02400  -16.49200 29.28300 1.000 14.20382 ? 199 LEU A HG   1 
ATOM   2812 H  HD11 . LEU A 1 176 ? -10.00900 -14.88100 27.87800 1.000 14.54017 ? 199 LEU A HD11 1 
ATOM   2813 H  HD12 . LEU A 1 176 ? -10.66800 -16.30900 27.65700 1.000 14.54017 ? 199 LEU A HD12 1 
ATOM   2814 H  HD13 . LEU A 1 176 ? -11.42500 -15.21000 28.51900 1.000 14.54017 ? 199 LEU A HD13 1 
ATOM   2815 H  HD21 . LEU A 1 176 ? -9.09300  -14.24000 30.00900 1.000 16.33688 ? 199 LEU A HD21 1 
ATOM   2816 H  HD22 . LEU A 1 176 ? -10.40100 -14.58500 30.84200 1.000 16.33688 ? 199 LEU A HD22 1 
ATOM   2817 H  HD23 . LEU A 1 176 ? -9.01500  -15.26300 31.22300 1.000 16.33688 ? 199 LEU A HD23 1 
ATOM   2818 N  N    . GLY A 1 177 ? -11.95000 -18.30700 32.94200 1.000 13.28019 ? 200 GLY A N    1 
ATOM   2819 C  CA   . GLY A 1 177 ? -13.05100 -19.10500 33.44900 1.000 14.64221 ? 200 GLY A CA   1 
ATOM   2820 C  C    . GLY A 1 177 ? -14.01300 -19.48500 32.34200 1.000 14.45660 ? 200 GLY A C    1 
ATOM   2821 O  O    . GLY A 1 177 ? -13.99700 -18.91500 31.25600 1.000 14.64612 ? 200 GLY A O    1 
ATOM   2822 H  H    . GLY A 1 177 ? -11.89300 -17.51700 33.27500 1.000 15.93428 ? 200 GLY A H    1 
ATOM   2823 H  HA2  . GLY A 1 177 ? -12.70600 -19.91700 33.85300 1.000 17.56870 ? 200 GLY A HA2  1 
ATOM   2824 H  HA3  . GLY A 1 177 ? -13.53600 -18.60000 34.12100 1.000 17.56870 ? 200 GLY A HA3  1 
ATOM   2825 N  N    . ASP A 1 178 ? -14.86700 -20.47800 32.61100 1.000 16.04971 ? 201 ASP A N    1 
ATOM   2826 C  CA   . ASP A 1 178 ? -15.69500 -21.02200 31.53600 1.000 16.68737 ? 201 ASP A CA   1 
ATOM   2827 C  C    . ASP A 1 178 ? -16.55600 -19.94000 30.88700 1.000 14.73857 ? 201 ASP A C    1 
ATOM   2828 O  O    . ASP A 1 178 ? -16.68100 -19.89000 29.66000 1.000 16.09712 ? 201 ASP A O    1 
ATOM   2829 C  CB   . ASP A 1 178 ? -16.56700 -22.16700 32.04000 1.000 19.81821 ? 201 ASP A CB   1 
ATOM   2830 C  CG   . ASP A 1 178 ? -15.82600 -23.48200 32.12600 1.000 22.99962 ? 201 ASP A CG   1 
ATOM   2831 O  OD1  . ASP A 1 178 ? -14.61200 -23.53800 31.83900 1.000 23.58121 ? 201 ASP A OD1  1 
ATOM   2832 O  OD2  . ASP A 1 178 ? -16.48000 -24.47900 32.48200 1.000 26.27201 ? 201 ASP A OD2  1 
ATOM   2833 H  H    . ASP A 1 178 ? -14.98200 -20.84200 33.38200 1.000 19.25771 ? 201 ASP A H    1 
ATOM   2834 H  HA   . ASP A 1 178 ? -15.09900 -21.38100 30.86000 1.000 20.02290 ? 201 ASP A HA   1 
ATOM   2835 H  HB2  . ASP A 1 178 ? -16.89200 -21.94900 32.92700 1.000 23.77990 ? 201 ASP A HB2  1 
ATOM   2836 H  HB3  . ASP A 1 178 ? -17.31500 -22.28500 31.43200 1.000 23.77990 ? 201 ASP A HB3  1 
ATOM   2837 N  N    . SER A 1 179 ? -17.20400 -19.09500 31.69800 1.000 14.06635 ? 202 SER A N    1 
ATOM   2838 C  CA   . SER A 1 179 ? -18.03800 -18.04100 31.13100 1.000 13.78659 ? 202 SER A CA   1 
ATOM   2839 C  C    . SER A 1 179 ? -17.20500 -17.11800 30.25400 1.000 12.96698 ? 202 SER A C    1 
ATOM   2840 O  O    . SER A 1 179 ? -17.62400 -16.72500 29.15600 1.000 12.72381 ? 202 SER A O    1 
ATOM   2841 C  CB   . SER A 1 179 ? -18.68100 -17.24300 32.26200 1.000 14.01605 ? 202 SER A CB   1 
ATOM   2842 O  OG   . SER A 1 179 ? -19.53900 -16.23300 31.77000 1.000 14.40063 ? 202 SER A OG   1 
ATOM   2843 H  H    . SER A 1 179 ? -17.17600 -19.11300 32.55700 1.000 16.87767 ? 202 SER A H    1 
ATOM   2844 H  HA   . SER A 1 179 ? -18.73900 -18.43700 30.59000 1.000 16.54196 ? 202 SER A HA   1 
ATOM   2845 H  HB2  . SER A 1 179 ? -19.19800 -17.84800 32.81700 1.000 16.81731 ? 202 SER A HB2  1 
ATOM   2846 H  HB3  . SER A 1 179 ? -17.98100 -16.82700 32.78800 1.000 16.81731 ? 202 SER A HB3  1 
ATOM   2847 H  HG   . SER A 1 179 ? -19.08700 -15.57400 31.51000 1.000 17.27880 ? 202 SER A HG   1 
ATOM   2848 N  N    . GLN A 1 180 ? -16.02300 -16.74700 30.74100 1.000 13.14467 ? 203 GLN A N    1 
ATOM   2849 C  CA   . GLN A 1 180 ? -15.19300 -15.77400 30.04000 1.000 11.98971 ? 203 GLN A CA   1 
ATOM   2850 C  C    . GLN A 1 180 ? -14.60300 -16.36400 28.76600 1.000 12.30669 ? 203 GLN A C    1 
ATOM   2851 O  O    . GLN A 1 180 ? -14.53200 -15.68300 27.73300 1.000 12.11238 ? 203 GLN A O    1 
ATOM   2852 C  CB   . GLN A 1 180 ? -14.10600 -15.26000 30.99000 1.000 12.62414 ? 203 GLN A CB   1 
ATOM   2853 C  CG   . GLN A 1 180 ? -14.62200 -14.37900 32.12300 1.000 13.97492 ? 203 GLN A CG   1 
ATOM   2854 C  CD   . GLN A 1 180 ? -15.31700 -15.16700 33.23000 1.000 16.08736 ? 203 GLN A CD   1 
ATOM   2855 O  OE1  . GLN A 1 180 ? -15.04800 -16.34400 33.44200 1.000 16.28579 ? 203 GLN A OE1  1 
ATOM   2856 N  NE2  . GLN A 1 180 ? -16.20900 -14.50600 33.94100 1.000 19.88649 ? 203 GLN A NE2  1 
ATOM   2857 H  H    . GLN A 1 180 ? -15.68000 -17.04300 31.47300 1.000 15.77166 ? 203 GLN A H    1 
ATOM   2858 H  HA   . GLN A 1 180 ? -15.73300 -15.01400 29.77300 1.000 14.38570 ? 203 GLN A HA   1 
ATOM   2859 H  HB2  . GLN A 1 180 ? -13.66000 -16.02200 31.39100 1.000 15.14702 ? 203 GLN A HB2  1 
ATOM   2860 H  HB3  . GLN A 1 180 ? -13.47100 -14.73600 30.47700 1.000 15.14702 ? 203 GLN A HB3  1 
ATOM   2861 H  HG2  . GLN A 1 180 ? -13.87300 -13.90600 32.51800 1.000 16.76795 ? 203 GLN A HG2  1 
ATOM   2862 H  HG3  . GLN A 1 180 ? -15.26100 -13.74500 31.76200 1.000 16.76795 ? 203 GLN A HG3  1 
ATOM   2863 H  HE21 . GLN A 1 180 ? -16.37000 -13.67900 33.76800 1.000 23.86184 ? 203 GLN A HE21 1 
ATOM   2864 H  HE22 . GLN A 1 180 ? -16.63000 -14.90200 34.57800 1.000 23.86184 ? 203 GLN A HE22 1 
ATOM   2865 N  N    . ARG A 1 181 ? -14.14400 -17.61400 28.83200 1.000 12.20103 ? 204 ARG A N    1 
ATOM   2866 C  CA   A ARG A 1 181 ? -13.67200 -18.30300 27.63700 0.640 11.83153 ? 204 ARG A CA   1 
ATOM   2867 C  CA   B ARG A 1 181 ? -13.66900 -18.29700 27.63500 0.360 12.71288 ? 204 ARG A CA   1 
ATOM   2868 C  C    . ARG A 1 181 ? -14.76500 -18.37100 26.58400 1.000 12.19352 ? 204 ARG A C    1 
ATOM   2869 O  O    . ARG A 1 181 ? -14.53100 -18.07100 25.40400 1.000 12.39047 ? 204 ARG A O    1 
ATOM   2870 C  CB   A ARG A 1 181 ? -13.20700 -19.71300 28.00300 0.640 12.38417 ? 204 ARG A CB   1 
ATOM   2871 C  CB   B ARG A 1 181 ? -13.17500 -19.70000 27.99400 0.360 14.44116 ? 204 ARG A CB   1 
ATOM   2872 C  CG   A ARG A 1 181 ? -12.77100 -20.52600 26.80800 0.640 13.35968 ? 204 ARG A CG   1 
ATOM   2873 C  CG   B ARG A 1 181 ? -12.73400 -20.50700 26.78800 0.360 16.41041 ? 204 ARG A CG   1 
ATOM   2874 C  CD   A ARG A 1 181 ? -12.30100 -21.89400 27.22900 0.640 15.27421 ? 204 ARG A CD   1 
ATOM   2875 C  CD   B ARG A 1 181 ? -12.02800 -21.79200 27.18600 0.360 18.49620 ? 204 ARG A CD   1 
ATOM   2876 N  NE   A ARG A 1 181 ? -13.38500 -22.71200 27.75400 0.640 16.20790 ? 204 ARG A NE   1 
ATOM   2877 N  NE   B ARG A 1 181 ? -12.90700 -22.72100 27.88700 0.360 19.71406 ? 204 ARG A NE   1 
ATOM   2878 C  CZ   A ARG A 1 181 ? -13.23700 -23.97100 28.13300 0.640 18.19145 ? 204 ARG A CZ   1 
ATOM   2879 C  CZ   B ARG A 1 181 ? -12.92700 -22.91100 29.20000 0.360 21.00512 ? 204 ARG A CZ   1 
ATOM   2880 N  NH1  A ARG A 1 181 ? -12.05600 -24.56600 28.09200 0.640 19.77748 ? 204 ARG A NH1  1 
ATOM   2881 N  NH1  B ARG A 1 181 ? -12.13300 -22.23100 30.01500 0.360 21.04789 ? 204 ARG A NH1  1 
ATOM   2882 N  NH2  A ARG A 1 181 ? -14.29900 -24.65200 28.54500 0.640 18.84667 ? 204 ARG A NH2  1 
ATOM   2883 N  NH2  B ARG A 1 181 ? -13.76200 -23.81000 29.71100 0.360 21.45755 ? 204 ARG A NH2  1 
ATOM   2884 H  H    A ARG A 1 181 ? -14.09700 -18.08100 29.55200 0.640 14.63929 ? 204 ARG A H    1 
ATOM   2885 H  H    B ARG A 1 181 ? -14.09900 -18.08300 29.55100 0.360 14.63929 ? 204 ARG A H    1 
ATOM   2886 H  HA   A ARG A 1 181 ? -12.91900 -17.81400 27.26900 0.640 14.19589 ? 204 ARG A HA   1 
ATOM   2887 H  HA   B ARG A 1 181 ? -12.92200 -17.80000 27.26500 0.360 15.25350 ? 204 ARG A HA   1 
ATOM   2888 H  HB2  A ARG A 1 181 ? -12.45300 -19.64700 28.61000 0.640 14.85905 ? 204 ARG A HB2  1 
ATOM   2889 H  HB2  B ARG A 1 181 ? -12.41700 -19.62200 28.59400 0.360 17.32745 ? 204 ARG A HB2  1 
ATOM   2890 H  HB3  A ARG A 1 181 ? -13.93800 -20.18300 28.43300 0.640 14.85905 ? 204 ARG A HB3  1 
ATOM   2891 H  HB3  B ARG A 1 181 ? -13.89400 -20.18400 28.43000 0.360 17.32745 ? 204 ARG A HB3  1 
ATOM   2892 H  HG2  A ARG A 1 181 ? -13.51900 -20.63300 26.20000 0.640 16.02967 ? 204 ARG A HG2  1 
ATOM   2893 H  HG2  B ARG A 1 181 ? -13.51300 -20.74100 26.25900 0.360 19.69054 ? 204 ARG A HG2  1 
ATOM   2894 H  HG3  A ARG A 1 181 ? -12.04000 -20.07500 26.35900 0.640 16.02967 ? 204 ARG A HG3  1 
ATOM   2895 H  HG3  B ARG A 1 181 ? -12.11900 -19.97700 26.25700 0.360 19.69054 ? 204 ARG A HG3  1 
ATOM   2896 H  HD2  A ARG A 1 181 ? -11.92300 -22.35100 26.46100 0.640 18.32711 ? 204 ARG A HD2  1 
ATOM   2897 H  HD2  B ARG A 1 181 ? -11.70000 -22.23400 26.38700 0.360 22.19349 ? 204 ARG A HD2  1 
ATOM   2898 H  HD3  A ARG A 1 181 ? -11.63000 -21.80000 27.92300 0.640 18.32711 ? 204 ARG A HD3  1 
ATOM   2899 H  HD3  B ARG A 1 181 ? -11.28800 -21.57800 27.77500 0.360 22.19349 ? 204 ARG A HD3  1 
ATOM   2900 H  HE   A ARG A 1 181 ? -14.16500 -22.35600 27.82300 0.640 19.44753 ? 204 ARG A HE   1 
ATOM   2901 H  HE   B ARG A 1 181 ? -13.45600 -23.18300 27.41200 0.360 23.65493 ? 204 ARG A HE   1 
ATOM   2902 H  HH11 A ARG A 1 181 ? -11.36600 -24.13400 27.81600 0.640 23.73103 ? 204 ARG A HH11 1 
ATOM   2903 H  HH11 B ARG A 1 181 ? -11.58700 -21.64800 29.69600 0.360 25.25552 ? 204 ARG A HH11 1 
ATOM   2904 H  HH12 A ARG A 1 181 ? -11.97900 -25.38500 28.34200 0.640 23.73103 ? 204 ARG A HH12 1 
ATOM   2905 H  HH12 B ARG A 1 181 ? -12.16500 -22.37200 30.86300 0.360 25.25552 ? 204 ARG A HH12 1 
ATOM   2906 H  HH21 A ARG A 1 181 ? -15.07200 -24.27400 28.56400 0.640 22.61405 ? 204 ARG A HH21 1 
ATOM   2907 H  HH21 B ARG A 1 181 ? -14.28000 -24.25900 29.19200 0.360 25.74711 ? 204 ARG A HH21 1 
ATOM   2908 H  HH22 A ARG A 1 181 ? -14.21500 -25.47100 28.79400 0.640 22.61405 ? 204 ARG A HH22 1 
ATOM   2909 H  HH22 B ARG A 1 181 ? -13.78400 -23.94200 30.56100 0.360 25.74711 ? 204 ARG A HH22 1 
ATOM   2910 N  N    . ALA A 1 182 ? -15.97000 -18.77000 26.99200 1.000 12.40564 ? 205 ALA A N    1 
ATOM   2911 C  CA   . ALA A 1 182 ? -17.06800 -18.84700 26.04000 1.000 12.98797 ? 205 ALA A CA   1 
ATOM   2912 C  C    . ALA A 1 182 ? -17.34700 -17.48700 25.43300 1.000 12.85390 ? 205 ALA A C    1 
ATOM   2913 O  O    . ALA A 1 182 ? -17.64200 -17.39000 24.23900 1.000 12.88808 ? 205 ALA A O    1 
ATOM   2914 C  CB   . ALA A 1 182 ? -18.31700 -19.40700 26.71900 1.000 14.39913 ? 205 ALA A CB   1 
ATOM   2915 H  H    . ALA A 1 182 ? -16.17000 -18.99500 27.79700 1.000 14.88481 ? 205 ALA A H    1 
ATOM   2916 H  HA   . ALA A 1 182 ? -16.82600 -19.45600 25.32400 1.000 15.58361 ? 205 ALA A HA   1 
ATOM   2917 H  HB1  . ALA A 1 182 ? -19.05200 -19.39600 26.08600 1.000 17.27701 ? 205 ALA A HB1  1 
ATOM   2918 H  HB2  . ALA A 1 182 ? -18.14000 -20.31700 27.00400 1.000 17.27701 ? 205 ALA A HB2  1 
ATOM   2919 H  HB3  . ALA A 1 182 ? -18.53300 -18.85600 27.48700 1.000 17.27701 ? 205 ALA A HB3  1 
ATOM   2920 N  N    . GLN A 1 183 ? -17.26500 -16.42400 26.24200 1.000 12.48240 ? 206 GLN A N    1 
ATOM   2921 C  CA   . GLN A 1 183 ? -17.51600 -15.08300 25.71600 1.000 11.98383 ? 206 GLN A CA   1 
ATOM   2922 C  C    . GLN A 1 183 ? -16.47200 -14.68200 24.67900 1.000 11.50004 ? 206 GLN A C    1 
ATOM   2923 O  O    . GLN A 1 183 ? -16.80800 -14.07200 23.65200 1.000 12.23602 ? 206 GLN A O    1 
ATOM   2924 C  CB   . GLN A 1 183 ? -17.53900 -14.06300 26.85700 1.000 13.12898 ? 206 GLN A CB   1 
ATOM   2925 C  CG   . GLN A 1 183 ? -17.83000 -12.63800 26.39700 1.000 12.45291 ? 206 GLN A CG   1 
ATOM   2926 C  CD   . GLN A 1 183 ? -19.21600 -12.50600 25.83100 1.000 13.29613 ? 206 GLN A CD   1 
ATOM   2927 O  OE1  . GLN A 1 183 ? -20.18400 -12.32700 26.57000 1.000 15.37637 ? 206 GLN A OE1  1 
ATOM   2928 N  NE2  . GLN A 1 183 ? -19.32500 -12.59000 24.51100 1.000 13.47821 ? 206 GLN A NE2  1 
ATOM   2929 H  H    . GLN A 1 183 ? -17.07100 -16.45300 27.07900 1.000 14.97693 ? 206 GLN A H    1 
ATOM   2930 H  HA   . GLN A 1 183 ? -18.38500 -15.08300 25.28700 1.000 14.37865 ? 206 GLN A HA   1 
ATOM   2931 H  HB2  . GLN A 1 183 ? -18.22900 -14.31700 27.48900 1.000 15.75283 ? 206 GLN A HB2  1 
ATOM   2932 H  HB3  . GLN A 1 183 ? -16.67200 -14.06200 27.29300 1.000 15.75283 ? 206 GLN A HB3  1 
ATOM   2933 H  HG2  . GLN A 1 183 ? -17.75300 -12.03600 27.15400 1.000 14.94154 ? 206 GLN A HG2  1 
ATOM   2934 H  HG3  . GLN A 1 183 ? -17.19500 -12.38800 25.70800 1.000 14.94154 ? 206 GLN A HG3  1 
ATOM   2935 H  HE21 . GLN A 1 183 ? -18.62400 -12.71300 24.02800 1.000 16.17191 ? 206 GLN A HE21 1 
ATOM   2936 H  HE22 . GLN A 1 183 ? -20.09700 -12.52100 24.13800 1.000 16.17191 ? 206 GLN A HE22 1 
ATOM   2937 N  N    . LEU A 1 184 ? -15.20000 -14.96500 24.95000 1.000 11.14207 ? 207 LEU A N    1 
ATOM   2938 C  CA   . LEU A 1 184 ? -14.15600 -14.66200 23.97800 1.000 11.33646 ? 207 LEU A CA   1 
ATOM   2939 C  C    . LEU A 1 184 ? -14.40400 -15.40400 22.67200 1.000 11.19320 ? 207 LEU A C    1 
ATOM   2940 O  O    . LEU A 1 184 ? -14.30300 -14.82600 21.58400 1.000 11.96486 ? 207 LEU A O    1 
ATOM   2941 C  CB   . LEU A 1 184 ? -12.78300 -15.01900 24.54200 1.000 11.16685 ? 207 LEU A CB   1 
ATOM   2942 C  CG   . LEU A 1 184 ? -11.62100 -14.75200 23.58600 1.000 11.12096 ? 207 LEU A CG   1 
ATOM   2943 C  CD1  . LEU A 1 184 ? -11.50700 -13.28100 23.23300 1.000 12.18974 ? 207 LEU A CD1  1 
ATOM   2944 C  CD2  . LEU A 1 184 ? -10.32600 -15.28800 24.19000 1.000 11.75610 ? 207 LEU A CD2  1 
ATOM   2945 H  H    . LEU A 1 184 ? -14.91900 -15.32700 25.67800 1.000 13.36854 ? 207 LEU A H    1 
ATOM   2946 H  HA   . LEU A 1 184 ? -14.16600 -13.70900 23.80000 1.000 13.60181 ? 207 LEU A HA   1 
ATOM   2947 H  HB2  . LEU A 1 184 ? -12.63200 -14.49300 25.34200 1.000 13.39827 ? 207 LEU A HB2  1 
ATOM   2948 H  HB3  . LEU A 1 184 ? -12.77400 -15.96400 24.75900 1.000 13.39827 ? 207 LEU A HB3  1 
ATOM   2949 H  HG   . LEU A 1 184 ? -11.78400 -15.21600 22.75000 1.000 13.34320 ? 207 LEU A HG   1 
ATOM   2950 H  HD11 . LEU A 1 184 ? -10.72500 -13.15000 22.67400 1.000 14.62574 ? 207 LEU A HD11 1 
ATOM   2951 H  HD12 . LEU A 1 184 ? -12.30600 -13.00800 22.75500 1.000 14.62574 ? 207 LEU A HD12 1 
ATOM   2952 H  HD13 . LEU A 1 184 ? -11.41900 -12.76600 24.05100 1.000 14.62574 ? 207 LEU A HD13 1 
ATOM   2953 H  HD21 . LEU A 1 184 ? -9.59400  -15.10500 23.58100 1.000 14.10537 ? 207 LEU A HD21 1 
ATOM   2954 H  HD22 . LEU A 1 184 ? -10.16800 -14.84800 25.04000 1.000 14.10537 ? 207 LEU A HD22 1 
ATOM   2955 H  HD23 . LEU A 1 184 ? -10.41300 -16.24500 24.32400 1.000 14.10537 ? 207 LEU A HD23 1 
ATOM   2956 N  N    . VAL A 1 185 ? -14.70600 -16.69700 22.76000 1.000 12.11869 ? 208 VAL A N    1 
ATOM   2957 C  CA   . VAL A 1 185 ? -14.94900 -17.49000 21.56300 1.000 13.22317 ? 208 VAL A CA   1 
ATOM   2958 C  C    . VAL A 1 185 ? -16.16900 -16.96800 20.81400 1.000 12.92354 ? 208 VAL A C    1 
ATOM   2959 O  O    . VAL A 1 185 ? -16.15200 -16.84200 19.58300 1.000 14.08409 ? 208 VAL A O    1 
ATOM   2960 C  CB   . VAL A 1 185 ? -15.08100 -18.97300 21.95100 1.000 14.55148 ? 208 VAL A CB   1 
ATOM   2961 C  CG1  . VAL A 1 185 ? -15.59900 -19.78600 20.78200 1.000 16.80160 ? 208 VAL A CG1  1 
ATOM   2962 C  CG2  . VAL A 1 185 ? -13.74000 -19.51500 22.42200 1.000 16.12774 ? 208 VAL A CG2  1 
ATOM   2963 H  H    . VAL A 1 185 ? -14.77700 -17.13600 23.49700 1.000 14.54047 ? 208 VAL A H    1 
ATOM   2964 H  HA   . VAL A 1 185 ? -14.19300 -17.40500 20.96100 1.000 15.86585 ? 208 VAL A HA   1 
ATOM   2965 H  HB   . VAL A 1 185 ? -15.71800 -19.05300 22.67900 1.000 17.45982 ? 208 VAL A HB   1 
ATOM   2966 H  HG11 . VAL A 1 185 ? -15.43600 -20.72600 20.95400 1.000 20.15997 ? 208 VAL A HG11 1 
ATOM   2967 H  HG12 . VAL A 1 185 ? -16.55100 -19.62800 20.68500 1.000 20.15997 ? 208 VAL A HG12 1 
ATOM   2968 H  HG13 . VAL A 1 185 ? -15.13400 -19.51100 19.97600 1.000 20.15997 ? 208 VAL A HG13 1 
ATOM   2969 H  HG21 . VAL A 1 185 ? -13.87700 -20.38200 22.83400 1.000 19.35134 ? 208 VAL A HG21 1 
ATOM   2970 H  HG22 . VAL A 1 185 ? -13.14900 -19.60100 21.65800 1.000 19.35134 ? 208 VAL A HG22 1 
ATOM   2971 H  HG23 . VAL A 1 185 ? -13.36000 -18.89900 23.06700 1.000 19.35134 ? 208 VAL A HG23 1 
ATOM   2972 N  N    . THR A 1 186 ? -17.24300 -16.66000 21.53600 1.000 13.19649 ? 209 THR A N    1 
ATOM   2973 C  CA   . THR A 1 186 ? -18.42300 -16.10400 20.88400 1.000 14.29351 ? 209 THR A CA   1 
ATOM   2974 C  C    . THR A 1 186 ? -18.08500 -14.80700 20.15900 1.000 12.81639 ? 209 THR A C    1 
ATOM   2975 O  O    . THR A 1 186 ? -18.50500 -14.59300 19.01800 1.000 13.99983 ? 209 THR A O    1 
ATOM   2976 C  CB   . THR A 1 186 ? -19.53100 -15.88600 21.91600 1.000 16.20519 ? 209 THR A CB   1 
ATOM   2977 O  OG1  . THR A 1 186 ? -19.97400 -17.15400 22.40700 1.000 19.65236 ? 209 THR A OG1  1 
ATOM   2978 C  CG2  . THR A 1 186 ? -20.72500 -15.15000 21.29700 1.000 18.06034 ? 209 THR A CG2  1 
ATOM   2979 H  H    . THR A 1 186 ? -17.31300 -16.76100 22.38700 1.000 15.83384 ? 209 THR A H    1 
ATOM   2980 H  HA   . THR A 1 186 ? -18.75300 -16.73400 20.22500 1.000 17.15026 ? 209 THR A HA   1 
ATOM   2981 H  HB   . THR A 1 186 ? -19.18700 -15.34600 22.64400 1.000 19.44428 ? 209 THR A HB   1 
ATOM   2982 H  HG1  . THR A 1 186 ? -20.41700 -17.05000 23.11300 1.000 23.58089 ? 209 THR A HG1  1 
ATOM   2983 H  HG21 . THR A 1 186 ? -21.45900 -15.11700 21.93000 1.000 21.67046 ? 209 THR A HG21 1 
ATOM   2984 H  HG22 . THR A 1 186 ? -20.47100 -14.24300 21.06300 1.000 21.67046 ? 209 THR A HG22 1 
ATOM   2985 H  HG23 . THR A 1 186 ? -21.02000 -15.61100 20.49600 1.000 21.67046 ? 209 THR A HG23 1 
ATOM   2986 N  N    . TRP A 1 187 ? -17.32900 -13.92500 20.80500 1.000 12.45221 ? 210 TRP A N    1 
ATOM   2987 C  CA   . TRP A 1 187 ? -16.96100 -12.67600 20.14800 1.000 12.13061 ? 210 TRP A CA   1 
ATOM   2988 C  C    . TRP A 1 187 ? -16.15300 -12.93600 18.88200 1.000 12.34885 ? 210 TRP A C    1 
ATOM   2989 O  O    . TRP A 1 187 ? -16.43300 -12.35400 17.82700 1.000 12.46089 ? 210 TRP A O    1 
ATOM   2990 C  CB   . TRP A 1 187 ? -16.17900 -11.78600 21.11400 1.000 12.55477 ? 210 TRP A CB   1 
ATOM   2991 C  CG   . TRP A 1 187 ? -17.01900 -11.01300 22.10800 1.000 12.52557 ? 210 TRP A CG   1 
ATOM   2992 C  CD1  . TRP A 1 187 ? -18.30800 -10.58900 21.94800 1.000 13.35048 ? 210 TRP A CD1  1 
ATOM   2993 C  CD2  . TRP A 1 187 ? -16.60800 -10.55600 23.40900 1.000 12.17739 ? 210 TRP A CD2  1 
ATOM   2994 N  NE1  . TRP A 1 187 ? -18.71900 -9.88300  23.05700 1.000 14.15233 ? 210 TRP A NE1  1 
ATOM   2995 C  CE2  . TRP A 1 187 ? -17.69600 -9.85500  23.96600 1.000 13.22084 ? 210 TRP A CE2  1 
ATOM   2996 C  CE3  . TRP A 1 187 ? -15.42200 -10.66000 24.15000 1.000 12.71140 ? 210 TRP A CE3  1 
ATOM   2997 C  CZ2  . TRP A 1 187 ? -17.64300 -9.28400  25.23100 1.000 13.84542 ? 210 TRP A CZ2  1 
ATOM   2998 C  CZ3  . TRP A 1 187 ? -15.37300 -10.08200 25.41300 1.000 13.32178 ? 210 TRP A CZ3  1 
ATOM   2999 C  CH2  . TRP A 1 187 ? -16.47600 -9.40700  25.93100 1.000 13.66734 ? 210 TRP A CH2  1 
ATOM   3000 H  H    . TRP A 1 187 ? -17.02300 -14.02200 21.60200 1.000 14.94070 ? 210 TRP A H    1 
ATOM   3001 H  HA   . TRP A 1 187 ? -17.77200 -12.20800 19.89600 1.000 14.55478 ? 210 TRP A HA   1 
ATOM   3002 H  HB2  . TRP A 1 187 ? -15.57200 -12.34600 21.62200 1.000 15.06378 ? 210 TRP A HB2  1 
ATOM   3003 H  HB3  . TRP A 1 187 ? -15.67600 -11.13900 20.59500 1.000 15.06378 ? 210 TRP A HB3  1 
ATOM   3004 H  HD1  . TRP A 1 187 ? -18.83300 -10.75400 21.19800 1.000 16.01863 ? 210 TRP A HD1  1 
ATOM   3005 H  HE1  . TRP A 1 187 ? -19.49100 -9.51900  23.16000 1.000 16.98084 ? 210 TRP A HE1  1 
ATOM   3006 H  HE3  . TRP A 1 187 ? -14.68300 -11.10700 23.80400 1.000 15.25173 ? 210 TRP A HE3  1 
ATOM   3007 H  HZ2  . TRP A 1 187 ? -18.37400 -8.83300  25.58800 1.000 16.61255 ? 210 TRP A HZ2  1 
ATOM   3008 H  HZ3  . TRP A 1 187 ? -14.59400 -10.14600 25.91800 1.000 15.98419 ? 210 TRP A HZ3  1 
ATOM   3009 H  HH2  . TRP A 1 187 ? -16.41700 -9.03000  26.77900 1.000 16.39886 ? 210 TRP A HH2  1 
ATOM   3010 N  N    . MET A 1 188 ? -15.15000 -13.81800 18.96800 1.000 11.79305 ? 211 MET A N    1 
ATOM   3011 C  CA   . MET A 1 188 ? -14.29400 -14.09200 17.81300 1.000 11.67165 ? 211 MET A CA   1 
ATOM   3012 C  C    . MET A 1 188 ? -15.06300 -14.76700 16.67800 1.000 12.64992 ? 211 MET A C    1 
ATOM   3013 O  O    . MET A 1 188 ? -14.79900 -14.48900 15.49900 1.000 12.44779 ? 211 MET A O    1 
ATOM   3014 C  CB   . MET A 1 188 ? -13.07400 -14.91700 18.22200 1.000 11.46868 ? 211 MET A CB   1 
ATOM   3015 C  CG   . MET A 1 188 ? -12.12600 -14.14800 19.15000 1.000 11.58460 ? 211 MET A CG   1 
ATOM   3016 S  SD   . MET A 1 188 ? -10.61600 -15.04200 19.52800 1.000 11.18124 ? 211 MET A SD   1 
ATOM   3017 C  CE   . MET A 1 188 ? -9.78200  -14.94300 17.94200 1.000 10.97128 ? 211 MET A CE   1 
ATOM   3018 H  H    . MET A 1 188 ? -14.94800 -14.26500 19.67500 1.000 14.14971 ? 211 MET A H    1 
ATOM   3019 H  HA   . MET A 1 188 ? -13.96200 -13.24100 17.48600 1.000 14.00403 ? 211 MET A HA   1 
ATOM   3020 H  HB2  . MET A 1 188 ? -13.37300 -15.71200 18.69000 1.000 13.76047 ? 211 MET A HB2  1 
ATOM   3021 H  HB3  . MET A 1 188 ? -12.57900 -15.16600 17.42600 1.000 13.76047 ? 211 MET A HB3  1 
ATOM   3022 H  HG2  . MET A 1 188 ? -11.87800 -13.31300 18.72400 1.000 13.89957 ? 211 MET A HG2  1 
ATOM   3023 H  HG3  . MET A 1 188 ? -12.58300 -13.97000 19.98700 1.000 13.89957 ? 211 MET A HG3  1 
ATOM   3024 H  HE1  . MET A 1 188 ? -8.86700  -15.25000 18.04600 1.000 13.16358 ? 211 MET A HE1  1 
ATOM   3025 H  HE2  . MET A 1 188 ? -10.24800 -15.50500 17.30400 1.000 13.16358 ? 211 MET A HE2  1 
ATOM   3026 H  HE3  . MET A 1 188 ? -9.78900  -14.02100 17.63900 1.000 13.16358 ? 211 MET A HE3  1 
ATOM   3027 N  N    . LYS A 1 189 ? -15.99900 -15.66500 17.00900 1.000 12.81452 ? 212 LYS A N    1 
ATOM   3028 C  CA   . LYS A 1 189 ? -16.82100 -16.30200 15.98300 1.000 13.43878 ? 212 LYS A CA   1 
ATOM   3029 C  C    . LYS A 1 189 ? -17.71400 -15.30100 15.27100 1.000 14.21793 ? 212 LYS A C    1 
ATOM   3030 O  O    . LYS A 1 189 ? -18.13400 -15.55500 14.14100 1.000 15.44534 ? 212 LYS A O    1 
ATOM   3031 C  CB   . LYS A 1 189 ? -17.68100 -17.42200 16.58600 1.000 15.44052 ? 212 LYS A CB   1 
ATOM   3032 C  CG   . LYS A 1 189 ? -16.90500 -18.68800 16.89300 1.000 17.35746 ? 212 LYS A CG   1 
ATOM   3033 C  CD   . LYS A 1 189 ? -17.69500 -19.69700 17.71500 1.000 21.62818 ? 212 LYS A CD   1 
ATOM   3034 C  CE   . LYS A 1 189 ? -18.92400 -20.20300 17.02200 1.000 25.52950 ? 212 LYS A CE   1 
ATOM   3035 N  NZ   . LYS A 1 189 ? -19.59300 -21.16000 17.94400 1.000 27.11201 ? 212 LYS A NZ   1 
ATOM   3036 H  H    . LYS A 1 189 ? -16.17300 -15.91700 17.81200 1.000 15.37547 ? 212 LYS A H    1 
ATOM   3037 H  HA   . LYS A 1 189 ? -16.23000 -16.70900 15.33100 1.000 16.12459 ? 212 LYS A HA   1 
ATOM   3038 H  HB2  . LYS A 1 189 ? -18.07000 -17.10500 17.41600 1.000 18.52667 ? 212 LYS A HB2  1 
ATOM   3039 H  HB3  . LYS A 1 189 ? -18.38300 -17.65000 15.95600 1.000 18.52667 ? 212 LYS A HB3  1 
ATOM   3040 H  HG2  . LYS A 1 189 ? -16.65700 -19.11400 16.05800 1.000 20.82701 ? 212 LYS A HG2  1 
ATOM   3041 H  HG3  . LYS A 1 189 ? -16.10900 -18.45400 17.39500 1.000 20.82701 ? 212 LYS A HG3  1 
ATOM   3042 H  HD2  . LYS A 1 189 ? -17.12700 -20.46000 17.90500 1.000 25.95187 ? 212 LYS A HD2  1 
ATOM   3043 H  HD3  . LYS A 1 189 ? -17.97500 -19.27700 18.54400 1.000 25.95187 ? 212 LYS A HD3  1 
ATOM   3044 H  HE2  . LYS A 1 189 ? -19.52700 -19.46800 16.82700 1.000 30.63345 ? 212 LYS A HE2  1 
ATOM   3045 H  HE3  . LYS A 1 189 ? -18.68300 -20.66100 16.20100 1.000 30.63345 ? 212 LYS A HE3  1 
ATOM   3046 H  HZ1  . LYS A 1 189 ? -20.34600 -21.46000 17.57800 1.000 32.53246 ? 212 LYS A HZ1  1 
ATOM   3047 H  HZ2  . LYS A 1 189 ? -19.05600 -21.85000 18.10800 1.000 32.53246 ? 212 LYS A HZ2  1 
ATOM   3048 H  HZ3  . LYS A 1 189 ? -19.78600 -20.75600 18.71400 1.000 32.53246 ? 212 LYS A HZ3  1 
ATOM   3049 N  N    . GLY A 1 190 ? -18.02400 -14.17800 15.90700 1.000 13.72882 ? 213 GLY A N    1 
ATOM   3050 C  CA   . GLY A 1 190 ? -18.82300 -13.13100 15.31700 1.000 14.29886 ? 213 GLY A CA   1 
ATOM   3051 C  C    . GLY A 1 190 ? -18.01200 -12.05100 14.63600 1.000 14.20246 ? 213 GLY A C    1 
ATOM   3052 O  O    . GLY A 1 190 ? -18.57600 -11.02300 14.24800 1.000 15.08069 ? 213 GLY A O    1 
ATOM   3053 H  H    . GLY A 1 190 ? -17.77100 -14.00000 16.71000 1.000 16.47264 ? 213 GLY A H    1 
ATOM   3054 H  HA2  . GLY A 1 190 ? -19.41600 -13.52200 14.65700 1.000 17.15668 ? 213 GLY A HA2  1 
ATOM   3055 H  HA3  . GLY A 1 190 ? -19.35600 -12.71300 16.01200 1.000 17.15668 ? 213 GLY A HA3  1 
ATOM   3056 N  N    . ASN A 1 191 ? -16.70800 -12.24800 14.46800 1.000 13.70498 ? 214 ASN A N    1 
ATOM   3057 C  CA   . ASN A 1 191 ? -15.88600 -11.27000 13.77100 1.000 12.89846 ? 214 ASN A CA   1 
ATOM   3058 C  C    . ASN A 1 191 ? -16.43700 -11.00200 12.37400 1.000 13.85206 ? 214 ASN A C    1 
ATOM   3059 O  O    . ASN A 1 191 ? -16.83600 -11.92200 11.66300 1.000 14.82835 ? 214 ASN A O    1 
ATOM   3060 C  CB   . ASN A 1 191 ? -14.45800 -11.78700 13.64400 1.000 13.19496 ? 214 ASN A CB   1 
ATOM   3061 C  CG   . ASN A 1 191 ? -13.55700 -10.79000 12.96000 1.000 12.81024 ? 214 ASN A CG   1 
ATOM   3062 O  OD1  . ASN A 1 191 ? -13.77500 -9.58900  13.07700 1.000 13.44365 ? 214 ASN A OD1  1 
ATOM   3063 N  ND2  . ASN A 1 191 ? -12.58300 -11.27400 12.18900 1.000 13.16168 ? 214 ASN A ND2  1 
ATOM   3064 H  H    . ASN A 1 191 ? -16.27700 -12.93700 14.74800 1.000 16.44403 ? 214 ASN A H    1 
ATOM   3065 H  HA   . ASN A 1 191 ? -15.88600 -10.44200 14.27500 1.000 15.47621 ? 214 ASN A HA   1 
ATOM   3066 H  HB2  . ASN A 1 191 ? -14.10100 -11.96000 14.52900 1.000 15.83200 ? 214 ASN A HB2  1 
ATOM   3067 H  HB3  . ASN A 1 191 ? -14.45900 -12.60400 13.12100 1.000 15.83200 ? 214 ASN A HB3  1 
ATOM   3068 H  HD21 . ASN A 1 191 ? -12.04800 -10.73700 11.78200 1.000 15.79206 ? 214 ASN A HD21 1 
ATOM   3069 H  HD22 . ASN A 1 191 ? -12.48800 -12.12400 12.09800 1.000 15.79206 ? 214 ASN A HD22 1 
ATOM   3070 N  N    . THR A 1 192 ? -16.43700 -9.73000  11.97600 1.000 13.62666 ? 215 THR A N    1 
ATOM   3071 C  CA   . THR A 1 192 ? -16.89400 -9.35100  10.64500 1.000 15.31167 ? 215 THR A CA   1 
ATOM   3072 C  C    . THR A 1 192 ? -15.76400 -9.06100  9.66100  1.000 15.00837 ? 215 THR A C    1 
ATOM   3073 O  O    . THR A 1 192 ? -16.04900 -8.82400  8.48700  1.000 17.21821 ? 215 THR A O    1 
ATOM   3074 C  CB   . THR A 1 192 ? -17.81400 -8.12500  10.69500 1.000 15.86197 ? 215 THR A CB   1 
ATOM   3075 O  OG1  . THR A 1 192 ? -17.03600 -6.94100  10.93600 1.000 16.00853 ? 215 THR A OG1  1 
ATOM   3076 C  CG2  . THR A 1 192 ? -18.89700 -8.27600  11.75600 1.000 17.36578 ? 215 THR A CG2  1 
ATOM   3077 H  H    . THR A 1 192 ? -16.17500 -9.07000  12.46200 1.000 16.35005 ? 215 THR A H    1 
ATOM   3078 H  HA   . THR A 1 192 ? -17.40800 -10.10200 10.30900 1.000 18.37205 ? 215 THR A HA   1 
ATOM   3079 H  HB   . THR A 1 192 ? -18.26700 -8.03700  9.84200  1.000 19.03241 ? 215 THR A HB   1 
ATOM   3080 H  HG1  . THR A 1 192 ? -16.76100 -6.93400  11.73000 1.000 19.20828 ? 215 THR A HG1  1 
ATOM   3081 H  HG21 . THR A 1 192 ? -19.54600 -7.56000  11.67200 1.000 20.83698 ? 215 THR A HG21 1 
ATOM   3082 H  HG22 . THR A 1 192 ? -19.35200 -9.12600  11.64700 1.000 20.83698 ? 215 THR A HG22 1 
ATOM   3083 H  HG23 . THR A 1 192 ? -18.50200 -8.24100  12.64100 1.000 20.83698 ? 215 THR A HG23 1 
ATOM   3084 N  N    . THR A 1 193 ? -14.49600 -9.08000  10.09600 1.000 14.04964 ? 216 THR A N    1 
ATOM   3085 C  CA   . THR A 1 193 ? -13.39000 -8.57200  9.28600  1.000 14.10889 ? 216 THR A CA   1 
ATOM   3086 C  C    . THR A 1 193 ? -12.49700 -9.64500  8.66800  1.000 14.57285 ? 216 THR A C    1 
ATOM   3087 O  O    . THR A 1 193 ? -11.51700 -9.29900  8.00000  1.000 15.04503 ? 216 THR A O    1 
ATOM   3088 C  CB   . THR A 1 193 ? -12.47300 -7.66100  10.12000 1.000 13.11104 ? 216 THR A CB   1 
ATOM   3089 O  OG1  . THR A 1 193 ? -11.76200 -8.46900  11.07300 1.000 13.80991 ? 216 THR A OG1  1 
ATOM   3090 C  CG2  . THR A 1 193 ? -13.26100 -6.58000  10.86000 1.000 15.41677 ? 216 THR A CG2  1 
ATOM   3091 H  H    . THR A 1 193 ? -14.25400 -9.38500  10.86300 1.000 16.85762 ? 216 THR A H    1 
ATOM   3092 H  HA   . THR A 1 193 ? -13.80300 -8.06500  8.57000  1.000 16.92872 ? 216 THR A HA   1 
ATOM   3093 H  HB   . THR A 1 193 ? -11.85300 -7.20800  9.52800  1.000 15.73130 ? 216 THR A HB   1 
ATOM   3094 H  HG1  . THR A 1 193 ? -10.96500 -8.57000  10.82700 1.000 16.56994 ? 216 THR A HG1  1 
ATOM   3095 H  HG21 . THR A 1 193 ? -12.65100 -5.95000  11.27400 1.000 18.49817 ? 216 THR A HG21 1 
ATOM   3096 H  HG22 . THR A 1 193 ? -13.83300 -6.10300  10.23900 1.000 18.49817 ? 216 THR A HG22 1 
ATOM   3097 H  HG23 . THR A 1 193 ? -13.81200 -6.98400  11.54900 1.000 18.49817 ? 216 THR A HG23 1 
ATOM   3098 N  N    . GLY A 1 194 ? -12.78400 -10.92500 8.87200  1.000 13.00881 ? 217 GLY A N    1 
ATOM   3099 C  CA   . GLY A 1 194 ? -11.82900 -11.97300 8.56000  1.000 13.35574 ? 217 GLY A CA   1 
ATOM   3100 C  C    . GLY A 1 194 ? -12.13300 -12.85300 7.36700  1.000 11.59524 ? 217 GLY A C    1 
ATOM   3101 O  O    . GLY A 1 194 ? -11.39800 -13.82200 7.13500  1.000 11.46406 ? 217 GLY A O    1 
ATOM   3102 H  H    . GLY A 1 194 ? -13.52900 -11.21000 9.19200  1.000 15.60862 ? 217 GLY A H    1 
ATOM   3103 H  HA2  . GLY A 1 194 ? -10.96900 -11.55700 8.39600  1.000 16.02493 ? 217 GLY A HA2  1 
ATOM   3104 H  HA3  . GLY A 1 194 ? -11.75700 -12.55400 9.33300  1.000 16.02493 ? 217 GLY A HA3  1 
ATOM   3105 N  N    . ALA A 1 195 ? -13.18300 -12.57300 6.60300  1.000 11.60671 ? 218 ALA A N    1 
ATOM   3106 C  CA   . ALA A 1 195 ? -13.61100 -13.51600 5.58100  1.000 11.55036 ? 218 ALA A CA   1 
ATOM   3107 C  C    . ALA A 1 195 ? -12.60100 -13.67200 4.45100  1.000 11.46492 ? 218 ALA A C    1 
ATOM   3108 O  O    . ALA A 1 195 ? -12.60600 -14.71200 3.78600  1.000 11.95220 ? 218 ALA A O    1 
ATOM   3109 C  CB   . ALA A 1 195 ? -14.96100 -13.07300 5.04800  1.000 12.30084 ? 218 ALA A CB   1 
ATOM   3110 H  H    . ALA A 1 195 ? -13.65500 -11.85600 6.65500  1.000 13.92610 ? 218 ALA A H    1 
ATOM   3111 H  HA   . ALA A 1 195 ? -13.70900 -14.39700 5.97500  1.000 13.85848 ? 218 ALA A HA   1 
ATOM   3112 H  HB1  . ALA A 1 195 ? -15.24400 -13.69000 4.35500  1.000 14.75906 ? 218 ALA A HB1  1 
ATOM   3113 H  HB2  . ALA A 1 195 ? -15.60300 -13.07500 5.77500  1.000 14.75906 ? 218 ALA A HB2  1 
ATOM   3114 H  HB3  . ALA A 1 195 ? -14.87800 -12.17900 4.68200  1.000 14.75906 ? 218 ALA A HB3  1 
ATOM   3115 N  N    . ALA A 1 196 ? -11.73500 -12.68400 4.21500  1.000 10.92562 ? 219 ALA A N    1 
ATOM   3116 C  CA   . ALA A 1 196 ? -10.73900 -12.76100 3.14700  1.000 11.04905 ? 219 ALA A CA   1 
ATOM   3117 C  C    . ALA A 1 196 ? -9.39800  -13.32500 3.60600  1.000 11.37374 ? 219 ALA A C    1 
ATOM   3118 O  O    . ALA A 1 196 ? -8.48500  -13.46500 2.78900  1.000 11.96684 ? 219 ALA A O    1 
ATOM   3119 C  CB   . ALA A 1 196 ? -10.50000 -11.37100 2.53800  1.000 11.98560 ? 219 ALA A CB   1 
ATOM   3120 H  H    . ALA A 1 196 ? -11.70500 -11.95300 4.66600  1.000 13.10879 ? 219 ALA A H    1 
ATOM   3121 H  HA   . ALA A 1 196 ? -11.09400 -13.34500 2.45800  1.000 13.25691 ? 219 ALA A HA   1 
ATOM   3122 H  HB1  . ALA A 1 196 ? -9.82800  -11.44200 1.84100  1.000 14.38077 ? 219 ALA A HB1  1 
ATOM   3123 H  HB2  . ALA A 1 196 ? -11.33200 -11.04200 2.16300  1.000 14.38077 ? 219 ALA A HB2  1 
ATOM   3124 H  HB3  . ALA A 1 196 ? -10.19100 -10.77000 3.23400  1.000 14.38077 ? 219 ALA A HB3  1 
ATOM   3125 N  N    . SER A 1 197 ? -9.24900  -13.64300 4.89000  1.000 10.81303 ? 220 SER A N    1 
ATOM   3126 C  CA   . SER A 1 197 ? -7.95700  -14.04600 5.43800  1.000 10.40091 ? 220 SER A CA   1 
ATOM   3127 C  C    . SER A 1 197 ? -7.94500  -15.55700 5.66200  1.000 10.79830 ? 220 SER A C    1 
ATOM   3128 O  O    . SER A 1 197 ? -8.16800  -16.30800 4.71300  1.000 10.81793 ? 220 SER A O    1 
ATOM   3129 C  CB   . SER A 1 197 ? -7.64700  -13.18500 6.66400  1.000 10.52197 ? 220 SER A CB   1 
ATOM   3130 O  OG   . SER A 1 197 ? -7.52200  -11.82300 6.27000  1.000 11.83133 ? 220 SER A OG   1 
ATOM   3131 H  H    . SER A 1 197 ? -9.88500  -13.63300 5.46800  1.000 12.97368 ? 220 SER A H    1 
ATOM   3132 H  HA   . SER A 1 197 ? -7.21900  -13.88500 4.83000  1.000 12.47915 ? 220 SER A HA   1 
ATOM   3133 H  HB2  . SER A 1 197 ? -8.36900  -13.26900 7.30600  1.000 12.62442 ? 220 SER A HB2  1 
ATOM   3134 H  HB3  . SER A 1 197 ? -6.81400  -13.48200 7.06200  1.000 12.62442 ? 220 SER A HB3  1 
ATOM   3135 H  HG   . SER A 1 197 ? -8.27900  -11.50300 6.09600  1.000 14.19565 ? 220 SER A HG   1 
ATOM   3136 N  N    . ILE A 1 198 ? -7.71500  -16.04200 6.88400  1.000 10.44521 ? 221 ILE A N    1 
ATOM   3137 C  CA   . ILE A 1 198 ? -7.64400  -17.49300 7.09200  1.000 10.37979 ? 221 ILE A CA   1 
ATOM   3138 C  C    . ILE A 1 198 ? -8.88900  -18.19600 6.56700  1.000 10.62342 ? 221 ILE A C    1 
ATOM   3139 O  O    . ILE A 1 198 ? -8.79000  -19.24100 5.90900  1.000 11.38901 ? 221 ILE A O    1 
ATOM   3140 C  CB   . ILE A 1 198 ? -7.36700  -17.81700 8.57800  1.000 10.58122 ? 221 ILE A CB   1 
ATOM   3141 C  CG1  . ILE A 1 198 ? -5.90700  -17.49900 8.90500  1.000 10.65333 ? 221 ILE A CG1  1 
ATOM   3142 C  CG2  . ILE A 1 198 ? -7.71400  -19.27600 8.90300  1.000 10.38244 ? 221 ILE A CG2  1 
ATOM   3143 C  CD1  . ILE A 1 198 ? -5.56800  -17.48500 10.39100 1.000 10.54512 ? 221 ILE A CD1  1 
ATOM   3144 H  H    . ILE A 1 198 ? -7.60000  -15.56700 7.59100  1.000 12.53230 ? 221 ILE A H    1 
ATOM   3145 H  HA   . ILE A 1 198 ? -6.89600  -17.83100 6.57500  1.000 12.45380 ? 221 ILE A HA   1 
ATOM   3146 H  HB   . ILE A 1 198 ? -7.93800  -17.26100 9.13100  1.000 12.69551 ? 221 ILE A HB   1 
ATOM   3147 H  HG12 . ILE A 1 198 ? -5.34500  -18.16900 8.48500  1.000 12.78204 ? 221 ILE A HG12 1 
ATOM   3148 H  HG13 . ILE A 1 198 ? -5.69700  -16.62000 8.55000  1.000 12.78204 ? 221 ILE A HG13 1 
ATOM   3149 H  HG21 . ILE A 1 198 ? -7.37700  -19.49100 9.78600  1.000 12.45698 ? 221 ILE A HG21 1 
ATOM   3150 H  HG22 . ILE A 1 198 ? -8.67800  -19.38300 8.88200  1.000 12.45698 ? 221 ILE A HG22 1 
ATOM   3151 H  HG23 . ILE A 1 198 ? -7.30200  -19.85300 8.24100  1.000 12.45698 ? 221 ILE A HG23 1 
ATOM   3152 H  HD11 . ILE A 1 198 ? -4.64500  -17.20800 10.50200 1.000 12.65219 ? 221 ILE A HD11 1 
ATOM   3153 H  HD12 . ILE A 1 198 ? -6.15700  -16.86100 10.84400 1.000 12.65219 ? 221 ILE A HD12 1 
ATOM   3154 H  HD13 . ILE A 1 198 ? -5.69200  -18.37700 10.75200 1.000 12.65219 ? 221 ILE A HD13 1 
ATOM   3155 N  N    A GLN A 1 199 ? -10.07300 -17.62800 6.82900  0.868 10.93506 ? 222 GLN A N    1 
ATOM   3156 N  N    B GLN A 1 199 ? -10.06500 -17.61800 6.80800  0.132 11.22965 ? 222 GLN A N    1 
ATOM   3157 C  CA   A GLN A 1 199 ? -11.32600 -18.23400 6.37600  0.868 11.28576 ? 222 GLN A CA   1 
ATOM   3158 C  CA   B GLN A 1 199 ? -11.30800 -18.25600 6.38700  0.132 11.89062 ? 222 GLN A CA   1 
ATOM   3159 C  C    A GLN A 1 199 ? -11.31800 -18.51700 4.88000  0.868 11.78800 ? 222 GLN A C    1 
ATOM   3160 C  C    B GLN A 1 199 ? -11.34600 -18.49600 4.88200  0.132 11.90020 ? 222 GLN A C    1 
ATOM   3161 O  O    A GLN A 1 199 ? -11.93000 -19.49000 4.42400  0.868 12.39136 ? 222 GLN A O    1 
ATOM   3162 O  O    B GLN A 1 199 ? -11.98600 -19.45100 4.42600  0.132 11.94678 ? 222 GLN A O    1 
ATOM   3163 C  CB   A GLN A 1 199 ? -12.50400 -17.30200 6.67300  0.868 12.94310 ? 222 GLN A CB   1 
ATOM   3164 C  CB   B GLN A 1 199 ? -12.48900 -17.38700 6.81700  0.132 12.69509 ? 222 GLN A CB   1 
ATOM   3165 C  CG   A GLN A 1 199 ? -12.89700 -17.18200 8.13900  0.868 13.67912 ? 222 GLN A CG   1 
ATOM   3166 C  CG   B GLN A 1 199 ? -13.83600 -18.07100 6.71000  0.132 13.10956 ? 222 GLN A CG   1 
ATOM   3167 C  CD   A GLN A 1 199 ? -13.91900 -16.06600 8.36800  0.868 14.77671 ? 222 GLN A CD   1 
ATOM   3168 C  CD   B GLN A 1 199 ? -14.93700 -17.36000 7.48700  0.132 14.49581 ? 222 GLN A CD   1 
ATOM   3169 O  OE1  A GLN A 1 199 ? -14.90000 -15.94600 7.61800  0.868 16.29796 ? 222 GLN A OE1  1 
ATOM   3170 O  OE1  B GLN A 1 199 ? -16.00300 -17.93100 7.72500  0.132 15.80029 ? 222 GLN A OE1  1 
ATOM   3171 N  NE2  A GLN A 1 199 ? -13.66900 -15.21700 9.37100  0.868 14.68346 ? 222 GLN A NE2  1 
ATOM   3172 N  NE2  B GLN A 1 199 ? -14.69200 -16.11000 7.87500  0.132 15.06229 ? 222 GLN A NE2  1 
ATOM   3173 H  H    A GLN A 1 199 ? -10.17600 -16.89400 7.26600  0.868 13.12012 ? 222 GLN A H    1 
ATOM   3174 H  H    B GLN A 1 199 ? -10.17000 -16.86500 7.21000  0.132 13.47363 ? 222 GLN A H    1 
ATOM   3175 H  HA   A GLN A 1 199 ? -11.43300 -19.06800 6.85900  0.868 13.54096 ? 222 GLN A HA   1 
ATOM   3176 H  HA   B GLN A 1 199 ? -11.38200 -19.12000 6.82000  0.132 14.26680 ? 222 GLN A HA   1 
ATOM   3177 H  HB2  A GLN A 1 199 ? -12.27400 -16.41200 6.36300  0.868 15.52977 ? 222 GLN A HB2  1 
ATOM   3178 H  HB2  B GLN A 1 199 ? -12.36300 -17.12900 7.74300  0.132 15.23216 ? 222 GLN A HB2  1 
ATOM   3179 H  HB3  A GLN A 1 199 ? -13.28000 -17.63100 6.19300  0.868 15.52977 ? 222 GLN A HB3  1 
ATOM   3180 H  HB3  B GLN A 1 199 ? -12.51400 -16.59800 6.25300  0.132 15.23216 ? 222 GLN A HB3  1 
ATOM   3181 H  HG2  A GLN A 1 199 ? -13.29100 -18.01900 8.43300  0.868 16.41300 ? 222 GLN A HG2  1 
ATOM   3182 H  HG2  B GLN A 1 199 ? -14.10100 -18.10000 5.77700  0.132 15.72952 ? 222 GLN A HG2  1 
ATOM   3183 H  HG3  A GLN A 1 199 ? -12.10800 -16.98300 8.66600  0.868 16.41300 ? 222 GLN A HG3  1 
ATOM   3184 H  HG3  B GLN A 1 199 ? -13.76000 -18.97300 7.06000  0.132 15.72952 ? 222 GLN A HG3  1 
ATOM   3185 H  HE21 A GLN A 1 199 ? -12.96100 -15.31400 9.85000  0.868 17.61820 ? 222 GLN A HE21 1 
ATOM   3186 H  HE21 B GLN A 1 199 ? -13.93900 -15.74100 7.68500  0.132 18.07280 ? 222 GLN A HE21 1 
ATOM   3187 H  HE22 A GLN A 1 199 ? -14.21500 -14.57400 9.53700  0.868 17.61820 ? 222 GLN A HE22 1 
ATOM   3188 H  HE22 B GLN A 1 199 ? -15.28600 -15.67200 8.31600  0.132 18.07280 ? 222 GLN A HE22 1 
ATOM   3189 N  N    . ALA A 1 200 ? -10.68200 -17.64500 4.09700  1.000 11.72313 ? 223 ALA A N    1 
ATOM   3190 C  CA   . ALA A 1 200 ? -10.69500 -17.79300 2.64100  1.000 12.16489 ? 223 ALA A CA   1 
ATOM   3191 C  C    . ALA A 1 200 ? -9.88300  -18.98700 2.16400  1.000 12.65485 ? 223 ALA A C    1 
ATOM   3192 O  O    . ALA A 1 200 ? -10.04600 -19.40300 1.01100  1.000 14.29552 ? 223 ALA A O    1 
ATOM   3193 C  CB   . ALA A 1 200 ? -10.20500 -16.50200 1.99100  1.000 12.89773 ? 223 ALA A CB   1 
ATOM   3194 H  H    . ALA A 1 200 ? -10.24000 -16.96500 4.38300  1.000 14.06581 ? 223 ALA A H    1 
ATOM   3195 H  HA   . ALA A 1 200 ? -11.60600 -17.93800 2.34000  1.000 14.59592 ? 223 ALA A HA   1 
ATOM   3196 H  HB1  . ALA A 1 200 ? -10.16500 -16.62700 1.03000  1.000 15.47533 ? 223 ALA A HB1  1 
ATOM   3197 H  HB2  . ALA A 1 200 ? -10.82400 -15.78600 2.20600  1.000 15.47533 ? 223 ALA A HB2  1 
ATOM   3198 H  HB3  . ALA A 1 200 ? -9.32300  -16.29000 2.33400  1.000 15.47533 ? 223 ALA A HB3  1 
ATOM   3199 N  N    . GLY A 1 201 ? -9.03500  -19.55800 3.01500  1.000 11.92849 ? 224 GLY A N    1 
ATOM   3200 C  CA   . GLY A 1 201 ? -8.24600  -20.72100 2.67600  1.000 12.02771 ? 224 GLY A CA   1 
ATOM   3201 C  C    . GLY A 1 201 ? -8.76800  -22.02400 3.23300  1.000 11.85359 ? 224 GLY A C    1 
ATOM   3202 O  O    . GLY A 1 201 ? -8.09100  -23.05100 3.08700  1.000 13.31076 ? 224 GLY A O    1 
ATOM   3203 H  H    . GLY A 1 201 ? -8.90000  -19.27600 3.81600  1.000 14.31224 ? 224 GLY A H    1 
ATOM   3204 H  HA2  . GLY A 1 201 ? -8.21300  -20.80400 1.71000  1.000 14.43130 ? 224 GLY A HA2  1 
ATOM   3205 H  HA3  . GLY A 1 201 ? -7.34500  -20.59400 3.01300  1.000 14.43130 ? 224 GLY A HA3  1 
ATOM   3206 N  N    . LEU A 1 202 ? -9.94200  -22.01900 3.85500  1.000 11.62529 ? 225 LEU A N    1 
ATOM   3207 C  CA   . LEU A 1 202 ? -10.53800 -23.18600 4.48200  1.000 12.02366 ? 225 LEU A CA   1 
ATOM   3208 C  C    . LEU A 1 202 ? -11.86100 -23.51600 3.81300  1.000 11.88274 ? 225 LEU A C    1 
ATOM   3209 O  O    . LEU A 1 202 ? -12.51100 -22.63800 3.23800  1.000 12.43582 ? 225 LEU A O    1 
ATOM   3210 C  CB   . LEU A 1 202 ? -10.83100 -22.91400 5.96400  1.000 12.60897 ? 225 LEU A CB   1 
ATOM   3211 C  CG   . LEU A 1 202 ? -9.65400  -22.42900 6.80200  1.000 13.03377 ? 225 LEU A CG   1 
ATOM   3212 C  CD1  . LEU A 1 202 ? -10.11400 -22.14300 8.20800  1.000 14.19218 ? 225 LEU A CD1  1 
ATOM   3213 C  CD2  . LEU A 1 202 ? -8.51200  -23.42600 6.77300  1.000 14.17894 ? 225 LEU A CD2  1 
ATOM   3214 H  H    . LEU A 1 202 ? -10.43200 -21.31700 3.92800  1.000 13.94840 ? 225 LEU A H    1 
ATOM   3215 H  HA   . LEU A 1 202 ? -9.92700  -23.93500 4.39800  1.000 14.42645 ? 225 LEU A HA   1 
ATOM   3216 H  HB2  . LEU A 1 202 ? -11.52000 -22.23300 6.01500  1.000 15.12881 ? 225 LEU A HB2  1 
ATOM   3217 H  HB3  . LEU A 1 202 ? -11.14800 -23.73800 6.36500  1.000 15.12881 ? 225 LEU A HB3  1 
ATOM   3218 H  HG   . LEU A 1 202 ? -9.30800  -21.60400 6.42700  1.000 15.63858 ? 225 LEU A HG   1 
ATOM   3219 H  HD11 . LEU A 1 202 ? -9.34900  -21.87800 8.74200  1.000 17.02867 ? 225 LEU A HD11 1 
ATOM   3220 H  HD12 . LEU A 1 202 ? -10.76700 -21.42600 8.18700  1.000 17.02867 ? 225 LEU A HD12 1 
ATOM   3221 H  HD13 . LEU A 1 202 ? -10.51400 -22.94500 8.57900  1.000 17.02867 ? 225 LEU A HD13 1 
ATOM   3222 H  HD21 . LEU A 1 202 ? -7.80700  -23.11500 7.36300  1.000 17.01278 ? 225 LEU A HD21 1 
ATOM   3223 H  HD22 . LEU A 1 202 ? -8.83800  -24.28800 7.07300  1.000 17.01278 ? 225 LEU A HD22 1 
ATOM   3224 H  HD23 . LEU A 1 202 ? -8.17700  -23.49600 5.86600  1.000 17.01278 ? 225 LEU A HD23 1 
ATOM   3225 N  N    . PRO A 1 203 ? -12.30300 -24.77900 3.87800  1.000 12.28072 ? 226 PRO A N    1 
ATOM   3226 C  CA   . PRO A 1 203 ? -13.63300 -25.12100 3.36100  1.000 13.04066 ? 226 PRO A CA   1 
ATOM   3227 C  C    . PRO A 1 203 ? -14.71500 -24.26600 4.00200  1.000 12.82840 ? 226 PRO A C    1 
ATOM   3228 O  O    . PRO A 1 203 ? -14.61900 -23.85500 5.16300  1.000 13.42347 ? 226 PRO A O    1 
ATOM   3229 C  CB   . PRO A 1 203 ? -13.79000 -26.60100 3.73700  1.000 14.49796 ? 226 PRO A CB   1 
ATOM   3230 C  CG   . PRO A 1 203 ? -12.37500 -27.11400 3.81900  1.000 14.08355 ? 226 PRO A CG   1 
ATOM   3231 C  CD   . PRO A 1 203 ? -11.58500 -25.96100 4.38900  1.000 12.92448 ? 226 PRO A CD   1 
ATOM   3232 H  HA   . PRO A 1 203 ? -13.66600 -25.02100 2.39700  1.000 15.64684 ? 226 PRO A HA   1 
ATOM   3233 H  HB2  . PRO A 1 203 ? -14.24100 -26.68100 4.59200  1.000 17.39560 ? 226 PRO A HB2  1 
ATOM   3234 H  HB3  . PRO A 1 203 ? -14.29200 -27.06700 3.05100  1.000 17.39560 ? 226 PRO A HB3  1 
ATOM   3235 H  HG2  . PRO A 1 203 ? -12.33500 -27.88700 4.40400  1.000 16.89831 ? 226 PRO A HG2  1 
ATOM   3236 H  HG3  . PRO A 1 203 ? -12.05600 -27.35100 2.93400  1.000 16.89831 ? 226 PRO A HG3  1 
ATOM   3237 H  HD2  . PRO A 1 203 ? -11.59600 -25.98000 5.35900  1.000 15.50742 ? 226 PRO A HD2  1 
ATOM   3238 H  HD3  . PRO A 1 203 ? -10.67000 -25.97500 4.06800  1.000 15.50742 ? 226 PRO A HD3  1 
ATOM   3239 N  N    . ALA A 1 204 ? -15.77200 -24.02900 3.22500  1.000 13.68777 ? 227 ALA A N    1 
ATOM   3240 C  CA   . ALA A 1 204 ? -16.87300 -23.18600 3.67400  1.000 14.75247 ? 227 ALA A CA   1 
ATOM   3241 C  C    . ALA A 1 204 ? -17.55800 -23.74400 4.91300  1.000 15.24741 ? 227 ALA A C    1 
ATOM   3242 O  O    . ALA A 1 204 ? -18.12300 -22.97600 5.69900  1.000 17.57848 ? 227 ALA A O    1 
ATOM   3243 C  CB   . ALA A 1 204 ? -17.89100 -23.04200 2.54800  1.000 15.32372 ? 227 ALA A CB   1 
ATOM   3244 H  H    . ALA A 1 204 ? -15.87500 -24.34500 2.43200  1.000 16.42337 ? 227 ALA A H    1 
ATOM   3245 H  HA   . ALA A 1 204 ? -16.51900 -22.31200 3.89900  1.000 17.70102 ? 227 ALA A HA   1 
ATOM   3246 H  HB1  . ALA A 1 204 ? -18.62500 -22.48700 2.85500  1.000 18.38652 ? 227 ALA A HB1  1 
ATOM   3247 H  HB2  . ALA A 1 204 ? -17.46100 -22.62800 1.78300  1.000 18.38652 ? 227 ALA A HB2  1 
ATOM   3248 H  HB3  . ALA A 1 204 ? -18.22100 -23.92200 2.30600  1.000 18.38652 ? 227 ALA A HB3  1 
ATOM   3249 N  N    . SER A 1 205 ? -17.52900 -25.06000 5.10700  1.000 15.35267 ? 228 SER A N    1 
ATOM   3250 C  CA   . SER A 1 205 ? -18.24600 -25.66600 6.22400  1.000 16.97270 ? 228 SER A CA   1 
ATOM   3251 C  C    . SER A 1 205 ? -17.53300 -25.50900 7.55900  1.000 16.94949 ? 228 SER A C    1 
ATOM   3252 O  O    . SER A 1 205 ? -18.15100 -25.74600 8.60400  1.000 19.59382 ? 228 SER A O    1 
ATOM   3253 C  CB   . SER A 1 205 ? -18.43200 -27.15600 5.96500  1.000 17.77598 ? 228 SER A CB   1 
ATOM   3254 O  OG   . SER A 1 205 ? -17.18300 -27.81600 5.96800  1.000 18.00422 ? 228 SER A OG   1 
ATOM   3255 H  H    . SER A 1 205 ? -17.10500 -25.61900 4.61000  1.000 18.42125 ? 228 SER A H    1 
ATOM   3256 H  HA   . SER A 1 205 ? -19.11400 -25.23700 6.28900  1.000 20.36529 ? 228 SER A HA   1 
ATOM   3257 H  HB2  . SER A 1 205 ? -18.99200 -27.53200 6.66200  1.000 21.32922 ? 228 SER A HB2  1 
ATOM   3258 H  HB3  . SER A 1 205 ? -18.85300 -27.27700 5.10000  1.000 21.32922 ? 228 SER A HB3  1 
ATOM   3259 H  HG   . SER A 1 205 ? -16.68300 -27.48700 5.37900  1.000 21.60311 ? 228 SER A HG   1 
ATOM   3260 N  N    . TRP A 1 206 ? -16.26300 -25.12700 7.55900  1.000 14.60948 ? 229 TRP A N    1 
ATOM   3261 C  CA   . TRP A 1 206 ? -15.52100 -25.04800 8.80700  1.000 14.22074 ? 229 TRP A CA   1 
ATOM   3262 C  C    . TRP A 1 206 ? -15.89600 -23.77900 9.56400  1.000 15.34811 ? 229 TRP A C    1 
ATOM   3263 O  O    . TRP A 1 206 ? -16.19400 -22.74400 8.97500  1.000 17.25199 ? 229 TRP A O    1 
ATOM   3264 C  CB   . TRP A 1 206 ? -14.01800 -25.09200 8.53900  1.000 14.30258 ? 229 TRP A CB   1 
ATOM   3265 C  CG   . TRP A 1 206 ? -13.52600 -26.39300 7.96300  1.000 13.81413 ? 229 TRP A CG   1 
ATOM   3266 C  CD1  . TRP A 1 206 ? -14.27300 -27.40000 7.39800  1.000 15.27226 ? 229 TRP A CD1  1 
ATOM   3267 C  CD2  . TRP A 1 206 ? -12.16300 -26.83700 7.90700  1.000 14.61184 ? 229 TRP A CD2  1 
ATOM   3268 N  NE1  . TRP A 1 206 ? -13.45300 -28.43000 6.99400  1.000 15.93208 ? 229 TRP A NE1  1 
ATOM   3269 C  CE2  . TRP A 1 206 ? -12.15700 -28.10900 7.29500  1.000 15.13689 ? 229 TRP A CE2  1 
ATOM   3270 C  CE3  . TRP A 1 206 ? -10.94900 -26.28100 8.31200  1.000 14.42583 ? 229 TRP A CE3  1 
ATOM   3271 C  CZ2  . TRP A 1 206 ? -10.98400 -28.82100 7.07800  1.000 16.36957 ? 229 TRP A CZ2  1 
ATOM   3272 C  CZ3  . TRP A 1 206 ? -9.78900  -27.00100 8.10500  1.000 15.98849 ? 229 TRP A CZ3  1 
ATOM   3273 C  CH2  . TRP A 1 206 ? -9.81600  -28.25200 7.48000  1.000 16.03581 ? 229 TRP A CH2  1 
ATOM   3274 H  H    . TRP A 1 206 ? -15.81400 -24.91200 6.85700  1.000 17.52943 ? 229 TRP A H    1 
ATOM   3275 H  HA   . TRP A 1 206 ? -15.73900 -25.80600 9.37100  1.000 17.06294 ? 229 TRP A HA   1 
ATOM   3276 H  HB2  . TRP A 1 206 ? -13.79600 -24.39000 7.90700  1.000 17.16115 ? 229 TRP A HB2  1 
ATOM   3277 H  HB3  . TRP A 1 206 ? -13.55000 -24.94600 9.37600  1.000 17.16115 ? 229 TRP A HB3  1 
ATOM   3278 H  HD1  . TRP A 1 206 ? -15.19800 -27.38800 7.30300  1.000 18.32476 ? 229 TRP A HD1  1 
ATOM   3279 H  HE1  . TRP A 1 206 ? -13.71300 -29.15700 6.61400  1.000 19.11655 ? 229 TRP A HE1  1 
ATOM   3280 H  HE3  . TRP A 1 206 ? -10.92100 -25.44300 8.71400  1.000 17.30904 ? 229 TRP A HE3  1 
ATOM   3281 H  HZ2  . TRP A 1 206 ? -10.99800 -29.65800 6.67300  1.000 19.64153 ? 229 TRP A HZ2  1 
ATOM   3282 H  HZ3  . TRP A 1 206 ? -8.97600  -26.64800 8.38700  1.000 19.18424 ? 229 TRP A HZ3  1 
ATOM   3283 H  HH2  . TRP A 1 206 ? -9.01600  -28.70400 7.33500  1.000 19.24103 ? 229 TRP A HH2  1 
ATOM   3284 N  N    . VAL A 1 207 ? -15.89200 -23.87400 10.88500 1.000 14.34863 ? 230 VAL A N    1 
ATOM   3285 C  CA   . VAL A 1 207 ? -16.28400 -22.76800 11.75000 1.000 14.31586 ? 230 VAL A CA   1 
ATOM   3286 C  C    . VAL A 1 207 ? -15.01900 -22.09400 12.26400 1.000 12.64225 ? 230 VAL A C    1 
ATOM   3287 O  O    . VAL A 1 207 ? -14.08200 -22.76800 12.72000 1.000 12.68780 ? 230 VAL A O    1 
ATOM   3288 C  CB   . VAL A 1 207 ? -17.16800 -23.26300 12.90600 1.000 16.02742 ? 230 VAL A CB   1 
ATOM   3289 C  CG1  . VAL A 1 207 ? -17.49800 -22.12100 13.87500 1.000 17.39623 ? 230 VAL A CG1  1 
ATOM   3290 C  CG2  . VAL A 1 207 ? -18.44700 -23.90000 12.35800 1.000 18.63615 ? 230 VAL A CG2  1 
ATOM   3291 H  H    . VAL A 1 207 ? -15.66200 -24.58300 11.31400 1.000 17.21640 ? 230 VAL A H    1 
ATOM   3292 H  HA   . VAL A 1 207 ? -16.78900 -22.11500 11.24200 1.000 17.17708 ? 230 VAL A HA   1 
ATOM   3293 H  HB   . VAL A 1 207 ? -16.68100 -23.93600 13.40600 1.000 19.23096 ? 230 VAL A HB   1 
ATOM   3294 H  HG11 . VAL A 1 207 ? -18.16000 -22.43000 14.51300 1.000 20.87353 ? 230 VAL A HG11 1 
ATOM   3295 H  HG12 . VAL A 1 207 ? -16.68900 -21.85700 14.33900 1.000 20.87353 ? 230 VAL A HG12 1 
ATOM   3296 H  HG13 . VAL A 1 207 ? -17.85000 -21.37100 13.37100 1.000 20.87353 ? 230 VAL A HG13 1 
ATOM   3297 H  HG21 . VAL A 1 207 ? -19.00600 -24.17500 13.10100 1.000 22.36143 ? 230 VAL A HG21 1 
ATOM   3298 H  HG22 . VAL A 1 207 ? -18.91600 -23.24800 11.81400 1.000 22.36143 ? 230 VAL A HG22 1 
ATOM   3299 H  HG23 . VAL A 1 207 ? -18.20900 -24.67100 11.81900 1.000 22.36143 ? 230 VAL A HG23 1 
ATOM   3300 N  N    . VAL A 1 208 ? -14.98600 -20.76500 12.20300 1.000 12.10808 ? 231 VAL A N    1 
ATOM   3301 C  CA   . VAL A 1 208 ? -13.78200 -19.99900 12.51000 1.000 12.66746 ? 231 VAL A CA   1 
ATOM   3302 C  C    . VAL A 1 208 ? -14.12800 -18.87000 13.46500 1.000 11.49494 ? 231 VAL A C    1 
ATOM   3303 O  O    . VAL A 1 208 ? -15.12000 -18.16600 13.26300 1.000 13.03478 ? 231 VAL A O    1 
ATOM   3304 C  CB   . VAL A 1 208 ? -13.15500 -19.40900 11.23000 1.000 14.16160 ? 231 VAL A CB   1 
ATOM   3305 C  CG1  . VAL A 1 208 ? -11.98300 -18.49300 11.57000 1.000 15.33317 ? 231 VAL A CG1  1 
ATOM   3306 C  CG2  . VAL A 1 208 ? -12.73600 -20.51900 10.29000 1.000 15.32777 ? 231 VAL A CG2  1 
ATOM   3307 H  H    . VAL A 1 208 ? -15.65900 -20.27800 11.98200 1.000 14.52774 ? 231 VAL A H    1 
ATOM   3308 H  HA   . VAL A 1 208 ? -13.14700 -20.58700 12.94900 1.000 15.19901 ? 231 VAL A HA   1 
ATOM   3309 H  HB   . VAL A 1 208 ? -13.81800 -18.86800 10.77400 1.000 16.99197 ? 231 VAL A HB   1 
ATOM   3310 H  HG11 . VAL A 1 208 ? -11.46000 -18.33800 10.76800 1.000 18.39785 ? 231 VAL A HG11 1 
ATOM   3311 H  HG12 . VAL A 1 208 ? -12.32700 -17.65100 11.90700 1.000 18.39785 ? 231 VAL A HG12 1 
ATOM   3312 H  HG13 . VAL A 1 208 ? -11.43400 -18.92000 12.24600 1.000 18.39785 ? 231 VAL A HG13 1 
ATOM   3313 H  HG21 . VAL A 1 208 ? -12.35200 -20.12800 9.49000  1.000 18.39137 ? 231 VAL A HG21 1 
ATOM   3314 H  HG22 . VAL A 1 208 ? -12.07800 -21.07700 10.73400 1.000 18.39137 ? 231 VAL A HG22 1 
ATOM   3315 H  HG23 . VAL A 1 208 ? -13.51500 -21.04800 10.05800 1.000 18.39137 ? 231 VAL A HG23 1 
ATOM   3316 N  N    . GLY A 1 209 ? -13.31600 -18.70500 14.50900 1.000 10.49443 ? 232 GLY A N    1 
ATOM   3317 C  CA   . GLY A 1 209 ? -13.25600 -17.45200 15.24200 1.000 10.65311 ? 232 GLY A CA   1 
ATOM   3318 C  C    . GLY A 1 209 ? -11.88700 -16.85700 15.02200 1.000 10.28300 ? 232 GLY A C    1 
ATOM   3319 O  O    . GLY A 1 209 ? -10.88300 -17.51900 15.26200 1.000 11.95646 ? 232 GLY A O    1 
ATOM   3320 H  H    . GLY A 1 209 ? -12.78800 -19.31200 14.81300 1.000 12.59137 ? 232 GLY A H    1 
ATOM   3321 H  HA2  . GLY A 1 209 ? -13.93300 -16.83800 14.91800 1.000 12.78179 ? 232 GLY A HA2  1 
ATOM   3322 H  HA3  . GLY A 1 209 ? -13.39600 -17.60600 16.18900 1.000 12.78179 ? 232 GLY A HA3  1 
ATOM   3323 N  N    . ASP A 1 210 ? -11.80500 -15.62600 14.52500 1.000 9.99585  ? 233 ASP A N    1 
ATOM   3324 C  CA   . ASP A 1 210 ? -10.50800 -15.06400 14.19100 1.000 9.95027  ? 233 ASP A CA   1 
ATOM   3325 C  C    . ASP A 1 210 ? -10.45800 -13.58600 14.54200 1.000 8.96979  ? 233 ASP A C    1 
ATOM   3326 O  O    . ASP A 1 210 ? -11.48400 -12.93300 14.74200 1.000 10.08968 ? 233 ASP A O    1 
ATOM   3327 C  CB   . ASP A 1 210 ? -10.16600 -15.23900 12.69200 1.000 10.30643 ? 233 ASP A CB   1 
ATOM   3328 C  CG   . ASP A 1 210 ? -10.84200 -14.19700 11.82100 1.000 10.02067 ? 233 ASP A CG   1 
ATOM   3329 O  OD1  . ASP A 1 210 ? -12.08200 -14.22400 11.73600 1.000 11.62947 ? 233 ASP A OD1  1 
ATOM   3330 O  OD2  . ASP A 1 210 ? -10.13500 -13.31500 11.26900 1.000 10.01266 ? 233 ASP A OD2  1 
ATOM   3331 H  H    . ASP A 1 210 ? -12.47700 -15.11000 14.37600 1.000 11.99307 ? 233 ASP A H    1 
ATOM   3332 H  HA   . ASP A 1 210 ? -9.84200  -15.52400 14.72500 1.000 11.93838 ? 233 ASP A HA   1 
ATOM   3333 H  HB2  . ASP A 1 210 ? -9.20700  -15.15500 12.57300 1.000 12.36577 ? 233 ASP A HB2  1 
ATOM   3334 H  HB3  . ASP A 1 210 ? -10.46100 -16.11500 12.39900 1.000 12.36577 ? 233 ASP A HB3  1 
ATOM   3335 N  N    . LYS A 1 211 ? -9.23700  -13.06800 14.57500 1.000 8.99850  ? 234 LYS A N    1 
ATOM   3336 C  CA   . LYS A 1 211 ? -8.98700  -11.63800 14.68400 1.000 9.62601  ? 234 LYS A CA   1 
ATOM   3337 C  C    . LYS A 1 211 ? -7.90800  -11.26600 13.67900 1.000 8.91223  ? 234 LYS A C    1 
ATOM   3338 O  O    . LYS A 1 211 ? -6.79300  -11.79500 13.74200 1.000 9.52836  ? 234 LYS A O    1 
ATOM   3339 C  CB   . LYS A 1 211 ? -8.52400  -11.24700 16.08800 1.000 10.42456 ? 234 LYS A CB   1 
ATOM   3340 C  CG   . LYS A 1 211 ? -8.25200  -9.74600  16.22700 1.000 10.62913 ? 234 LYS A CG   1 
ATOM   3341 C  CD   . LYS A 1 211 ? -9.53900  -8.93600  16.24900 1.000 11.49851 ? 234 LYS A CD   1 
ATOM   3342 C  CE   . LYS A 1 211 ? -9.31300  -7.44700  15.94800 1.000 11.92577 ? 234 LYS A CE   1 
ATOM   3343 N  NZ   . LYS A 1 211 ? -9.15500  -7.21000  14.49800 1.000 11.69975 ? 234 LYS A NZ   1 
ATOM   3344 H  H    . LYS A 1 211 ? -8.51800  -13.53800 14.53400 1.000 10.79625 ? 234 LYS A H    1 
ATOM   3345 H  HA   . LYS A 1 211 ? -9.80600  -11.15900 14.48100 1.000 11.54926 ? 234 LYS A HA   1 
ATOM   3346 H  HB2  . LYS A 1 211 ? -9.21400  -11.48700 16.72600 1.000 12.50753 ? 234 LYS A HB2  1 
ATOM   3347 H  HB3  . LYS A 1 211 ? -7.70300  -11.72100 16.29200 1.000 12.50753 ? 234 LYS A HB3  1 
ATOM   3348 H  HG2  . LYS A 1 211 ? -7.77700  -9.58300  17.05700 1.000 12.75301 ? 234 LYS A HG2  1 
ATOM   3349 H  HG3  . LYS A 1 211 ? -7.71700  -9.44700  15.47500 1.000 12.75301 ? 234 LYS A HG3  1 
ATOM   3350 H  HD2  . LYS A 1 211 ? -10.14500 -9.28800  15.57800 1.000 13.79626 ? 234 LYS A HD2  1 
ATOM   3351 H  HD3  . LYS A 1 211 ? -9.94100  -9.00600  17.12800 1.000 13.79626 ? 234 LYS A HD3  1 
ATOM   3352 H  HE2  . LYS A 1 211 ? -10.07600 -6.93600  16.26000 1.000 14.30898 ? 234 LYS A HE2  1 
ATOM   3353 H  HE3  . LYS A 1 211 ? -8.50700  -7.14700  16.39700 1.000 14.30898 ? 234 LYS A HE3  1 
ATOM   3354 H  HZ1  . LYS A 1 211 ? -8.44000  -7.64500  14.19500 1.000 14.03775 ? 234 LYS A HZ1  1 
ATOM   3355 H  HZ2  . LYS A 1 211 ? -9.87500  -7.49900  14.06200 1.000 14.03775 ? 234 LYS A HZ2  1 
ATOM   3356 H  HZ3  . LYS A 1 211 ? -9.05100  -6.34000  14.34100 1.000 14.03775 ? 234 LYS A HZ3  1 
ATOM   3357 N  N    . THR A 1 212 ? -8.23000  -10.33200 12.78400 1.000 9.06589  ? 235 THR A N    1 
ATOM   3358 C  CA   . THR A 1 212 ? -7.29400  -9.85300  11.78400 1.000 9.76932  ? 235 THR A CA   1 
ATOM   3359 C  C    . THR A 1 212 ? -6.43600  -8.70800  12.32700 1.000 9.84551  ? 235 THR A C    1 
ATOM   3360 O  O    . THR A 1 212 ? -6.73500  -8.07700  13.34100 1.000 10.42611 ? 235 THR A O    1 
ATOM   3361 C  CB   . THR A 1 212 ? -8.07100  -9.31200  10.58400 1.000 10.95328 ? 235 THR A CB   1 
ATOM   3362 O  OG1  . THR A 1 212 ? -9.03500  -8.35600  11.04700 1.000 13.12387 ? 235 THR A OG1  1 
ATOM   3363 C  CG2  . THR A 1 212 ? -8.78000  -10.42600 9.84800  1.000 12.27505 ? 235 THR A CG2  1 
ATOM   3364 H  H    . THR A 1 212 ? -9.00300  -9.95700  12.73900 1.000 10.87712 ? 235 THR A H    1 
ATOM   3365 H  HA   . THR A 1 212 ? -6.71900  -10.59000 11.52800 1.000 11.72123 ? 235 THR A HA   1 
ATOM   3366 H  HB   . THR A 1 212 ? -7.45700  -8.89200  9.96200  1.000 13.14198 ? 235 THR A HB   1 
ATOM   3367 H  HG1  . THR A 1 212 ? -8.64300  -7.68500  11.36700 1.000 15.74669 ? 235 THR A HG1  1 
ATOM   3368 H  HG21 . THR A 1 212 ? -9.20900  -10.07600 9.05100  1.000 14.72812 ? 235 THR A HG21 1 
ATOM   3369 H  HG22 . THR A 1 212 ? -8.14300  -11.11000 9.58900  1.000 14.72812 ? 235 THR A HG22 1 
ATOM   3370 H  HG23 . THR A 1 212 ? -9.45500  -10.82400 10.42000 1.000 14.72812 ? 235 THR A HG23 1 
ATOM   3371 N  N    . GLY A 1 213 ? -5.37000  -8.42700  11.59500 1.000 10.15667 ? 236 GLY A N    1 
ATOM   3372 C  CA   . GLY A 1 213 ? -4.61400  -7.20600  11.78500 1.000 10.35469 ? 236 GLY A CA   1 
ATOM   3373 C  C    . GLY A 1 213 ? -4.05400  -6.68200  10.48500 1.000 11.19110 ? 236 GLY A C    1 
ATOM   3374 O  O    . GLY A 1 213 ? -3.74500  -7.43800  9.55800  1.000 11.88685 ? 236 GLY A O    1 
ATOM   3375 H  H    . GLY A 1 213 ? -5.06200  -8.93400  10.97300 1.000 12.18605 ? 236 GLY A H    1 
ATOM   3376 H  HA2  . GLY A 1 213 ? -5.18900  -6.52500  12.16800 1.000 12.42368 ? 236 GLY A HA2  1 
ATOM   3377 H  HA3  . GLY A 1 213 ? -3.87600  -7.37400  12.39200 1.000 12.42368 ? 236 GLY A HA3  1 
ATOM   3378 N  N    A SER A 1 214 ? -3.91200  -5.36900  10.42200 0.559 11.05198 ? 237 SER A N    1 
ATOM   3379 N  N    B SER A 1 214 ? -3.93400  -5.35600  10.42100 0.238 11.55807 ? 237 SER A N    1 
ATOM   3380 N  N    C SER A 1 214 ? -3.90100  -5.36000  10.43600 0.203 11.52054 ? 237 SER A N    1 
ATOM   3381 C  CA   A SER A 1 214 ? -3.25500  -4.72400  9.30000  0.559 12.35994 ? 237 SER A CA   1 
ATOM   3382 C  CA   B SER A 1 214 ? -3.36000  -4.63600  9.29400  0.238 12.22918 ? 237 SER A CA   1 
ATOM   3383 C  CA   C SER A 1 214 ? -3.35800  -4.64300  9.29300  0.203 12.17144 ? 237 SER A CA   1 
ATOM   3384 C  C    A SER A 1 214 ? -2.54200  -3.48500  9.81700  0.559 11.51141 ? 237 SER A C    1 
ATOM   3385 C  C    B SER A 1 214 ? -2.54200  -3.47200  9.83900  0.238 11.53726 ? 237 SER A C    1 
ATOM   3386 C  C    C SER A 1 214 ? -2.55600  -3.46100  9.82200  0.203 11.58064 ? 237 SER A C    1 
ATOM   3387 O  O    A SER A 1 214 ? -2.95800  -2.87000  10.80300 0.559 12.15028 ? 237 SER A O    1 
ATOM   3388 O  O    B SER A 1 214 ? -2.88200  -2.89200  10.87300 0.238 11.71669 ? 237 SER A O    1 
ATOM   3389 O  O    C SER A 1 214 ? -2.92800  -2.86000  10.83400 0.203 11.85461 ? 237 SER A O    1 
ATOM   3390 C  CB   A SER A 1 214 ? -4.25400  -4.34100  8.21300  0.559 15.58580 ? 237 SER A CB   1 
ATOM   3391 C  CB   B SER A 1 214 ? -4.45200  -4.07000  8.37200  0.238 13.72428 ? 237 SER A CB   1 
ATOM   3392 C  CB   C SER A 1 214 ? -4.49000  -4.12700  8.39800  0.203 13.65848 ? 237 SER A CB   1 
ATOM   3393 O  OG   A SER A 1 214 ? -5.18000  -3.41500  8.73000  0.559 16.84814 ? 237 SER A OG   1 
ATOM   3394 O  OG   B SER A 1 214 ? -5.16700  -5.09800  7.70800  0.238 14.17739 ? 237 SER A OG   1 
ATOM   3395 O  OG   C SER A 1 214 ? -3.98700  -3.32000  7.34800  0.203 14.40918 ? 237 SER A OG   1 
ATOM   3396 H  H    A SER A 1 214 ? -4.19100  -4.82300  11.02400 0.559 13.26043 ? 237 SER A H    1 
ATOM   3397 H  H    B SER A 1 214 ? -4.19100  -4.83000  11.05000 0.238 13.86773 ? 237 SER A H    1 
ATOM   3398 H  H    C SER A 1 214 ? -4.11500  -4.83500  11.08300 0.203 13.82270 ? 237 SER A H    1 
ATOM   3399 H  HA   A SER A 1 214 ? -2.59900  -5.32200  8.90900  0.559 14.82998 ? 237 SER A HA   1 
ATOM   3400 H  HA   B SER A 1 214 ? -2.79000  -5.23100  8.78100  0.238 14.67307 ? 237 SER A HA   1 
ATOM   3401 H  HA   C SER A 1 214 ? -2.77700  -5.21800  8.77100  0.203 14.60378 ? 237 SER A HA   1 
ATOM   3402 H  HB2  A SER A 1 214 ? -3.77900  -3.94000  7.46800  0.559 18.70101 ? 237 SER A HB2  1 
ATOM   3403 H  HB2  B SER A 1 214 ? -5.07500  -3.55300  8.90700  0.238 16.46718 ? 237 SER A HB2  1 
ATOM   3404 H  HB2  C SER A 1 214 ? -4.95800  -4.88500  8.01500  0.203 16.38822 ? 237 SER A HB2  1 
ATOM   3405 H  HB3  A SER A 1 214 ? -4.72500  -5.13500  7.91600  0.559 18.70101 ? 237 SER A HB3  1 
ATOM   3406 H  HB3  B SER A 1 214 ? -4.03500  -3.50100  7.70700  0.238 16.46718 ? 237 SER A HB3  1 
ATOM   3407 H  HB3  C SER A 1 214 ? -5.10000  -3.59800  8.93600  0.203 16.38822 ? 237 SER A HB3  1 
ATOM   3408 H  HG   A SER A 1 214 ? -5.71700  -3.17900  8.12800  0.559 20.21582 ? 237 SER A HG   1 
ATOM   3409 H  HG   B SER A 1 214 ? -4.70300  -5.79700  7.67700  0.238 17.01092 ? 237 SER A HG   1 
ATOM   3410 H  HG   C SER A 1 214 ? -3.35400  -3.71500  6.96100  0.203 17.28907 ? 237 SER A HG   1 
ATOM   3411 N  N    . GLY A 1 215 ? -1.46400  -3.13100  9.14800  1.000 10.97524 ? 238 GLY A N    1 
ATOM   3412 C  CA   . GLY A 1 215 ? -0.66600  -2.00000  9.57100  1.000 11.54574 ? 238 GLY A CA   1 
ATOM   3413 C  C    . GLY A 1 215 ? 0.32600   -1.55900  8.52600  1.000 11.06115 ? 238 GLY A C    1 
ATOM   3414 O  O    . GLY A 1 215 ? 0.20900   -1.89500  7.34600  1.000 12.21832 ? 238 GLY A O    1 
ATOM   3415 H  H    . GLY A 1 215 ? -1.17500  -3.53100  8.44400  1.000 13.16834 ? 238 GLY A H    1 
ATOM   3416 H  HA2  . GLY A 1 215 ? -1.25100  -1.25200  9.76900  1.000 13.85294 ? 238 GLY A HA2  1 
ATOM   3417 H  HA3  . GLY A 1 215 ? -0.17500  -2.23800  10.37300 1.000 13.85294 ? 238 GLY A HA3  1 
ATOM   3418 N  N    . GLY A 1 216 ? 1.29700   -0.76700  8.97300  1.000 11.83410 ? 239 GLY A N    1 
ATOM   3419 C  CA   . GLY A 1 216 ? 2.33400   -0.28000  8.08600  1.000 12.12566 ? 239 GLY A CA   1 
ATOM   3420 C  C    . GLY A 1 216 ? 3.10800   -1.41600  7.45900  1.000 11.63248 ? 239 GLY A C    1 
ATOM   3421 O  O    . GLY A 1 216 ? 3.06300   -2.56600  7.88300  1.000 11.81437 ? 239 GLY A O    1 
ATOM   3422 H  H    . GLY A 1 216 ? 1.37400   -0.50000  9.78700  1.000 14.19898 ? 239 GLY A H    1 
ATOM   3423 H  HA2  . GLY A 1 216 ? 1.93300   0.24800   7.37800  1.000 14.54885 ? 239 GLY A HA2  1 
ATOM   3424 H  HA3  . GLY A 1 216 ? 2.95200   0.27700   8.58500  1.000 14.54885 ? 239 GLY A HA3  1 
ATOM   3425 N  N    . TYR A 1 217 ? 3.86000   -1.07300  6.41600  1.000 12.80319 ? 240 TYR A N    1 
ATOM   3426 C  CA   . TYR A 1 217 ? 4.66900   -2.04800  5.69800  1.000 11.96448 ? 240 TYR A CA   1 
ATOM   3427 C  C    . TYR A 1 217 ? 3.81200   -3.20100  5.17400  1.000 11.09259 ? 240 TYR A C    1 
ATOM   3428 O  O    . TYR A 1 217 ? 4.25600   -4.34700  5.08000  1.000 12.21234 ? 240 TYR A O    1 
ATOM   3429 C  CB   . TYR A 1 217 ? 5.87500   -2.50700  6.52400  1.000 12.03845 ? 240 TYR A CB   1 
ATOM   3430 C  CG   . TYR A 1 217 ? 6.91900   -1.41000  6.63500  1.000 13.08755 ? 240 TYR A CG   1 
ATOM   3431 C  CD1  . TYR A 1 217 ? 6.78800   -0.37400  7.56500  1.000 13.82082 ? 240 TYR A CD1  1 
ATOM   3432 C  CD2  . TYR A 1 217 ? 7.99800   -1.37700  5.76400  1.000 13.66509 ? 240 TYR A CD2  1 
ATOM   3433 C  CE1  . TYR A 1 217 ? 7.72400   0.63800   7.63900  1.000 14.60722 ? 240 TYR A CE1  1 
ATOM   3434 C  CE2  . TYR A 1 217 ? 8.94600   -0.36800  5.83100  1.000 14.06796 ? 240 TYR A CE2  1 
ATOM   3435 C  CZ   . TYR A 1 217 ? 8.80900   0.63800   6.76400  1.000 15.23908 ? 240 TYR A CZ   1 
ATOM   3436 O  OH   . TYR A 1 217 ? 9.74500   1.64600   6.82600  1.000 18.53451 ? 240 TYR A OH   1 
ATOM   3437 H  H    . TYR A 1 217 ? 3.91600   -0.27300  6.10400  1.000 15.36187 ? 240 TYR A H    1 
ATOM   3438 H  HA   . TYR A 1 217 ? 5.04900   -1.62900  4.91000  1.000 14.35543 ? 240 TYR A HA   1 
ATOM   3439 H  HB2  . TYR A 1 217 ? 5.58100   -2.74200  7.41800  1.000 14.44419 ? 240 TYR A HB2  1 
ATOM   3440 H  HB3  . TYR A 1 217 ? 6.28400   -3.27500  6.09600  1.000 14.44419 ? 240 TYR A HB3  1 
ATOM   3441 H  HD1  . TYR A 1 217 ? 6.06000   -0.36700  8.14300  1.000 16.58303 ? 240 TYR A HD1  1 
ATOM   3442 H  HD2  . TYR A 1 217 ? 8.08700   -2.04500  5.12300  1.000 16.39615 ? 240 TYR A HD2  1 
ATOM   3443 H  HE1  . TYR A 1 217 ? 7.63100   1.31600   8.26900  1.000 17.52671 ? 240 TYR A HE1  1 
ATOM   3444 H  HE2  . TYR A 1 217 ? 9.67100   -0.37000  5.24900  1.000 16.87961 ? 240 TYR A HE2  1 
ATOM   3445 H  HH   . TYR A 1 217 ? 10.28200  1.58000   6.18300  1.000 22.23947 ? 240 TYR A HH   1 
ATOM   3446 N  N    . GLY A 1 218 ? 2.57000   -2.89800  4.81500  1.000 11.75690 ? 241 GLY A N    1 
ATOM   3447 C  CA   . GLY A 1 218 ? 1.70100   -3.91000  4.24500  1.000 11.74879 ? 241 GLY A CA   1 
ATOM   3448 C  C    . GLY A 1 218 ? 1.48100   -5.08000  5.17500  1.000 11.61747 ? 241 GLY A C    1 
ATOM   3449 O  O    . GLY A 1 218 ? 1.22100   -6.19800  4.71800  1.000 11.81292 ? 241 GLY A O    1 
ATOM   3450 H  H    . GLY A 1 218 ? 2.21200   -2.12000  4.89100  1.000 14.10633 ? 241 GLY A H    1 
ATOM   3451 H  HA2  . GLY A 1 218 ? 0.83900   -3.51400  4.04400  1.000 14.09660 ? 241 GLY A HA2  1 
ATOM   3452 H  HA3  . GLY A 1 218 ? 2.09400   -4.24400  3.42400  1.000 14.09660 ? 241 GLY A HA3  1 
ATOM   3453 N  N    . THR A 1 219 ? 1.57100   -4.84900  6.48200  1.000 11.55520 ? 242 THR A N    1 
ATOM   3454 C  CA   . THR A 1 219 ? 1.44300   -5.93600  7.43400  1.000 10.28023 ? 242 THR A CA   1 
ATOM   3455 C  C    . THR A 1 219 ? 0.00600   -6.43100  7.40500  1.000 10.13932 ? 242 THR A C    1 
ATOM   3456 O  O    . THR A 1 219 ? -0.93900  -5.63500  7.45300  1.000 11.03514 ? 242 THR A O    1 
ATOM   3457 C  CB   . THR A 1 219 ? 1.86000   -5.46700  8.82500  1.000 10.48819 ? 242 THR A CB   1 
ATOM   3458 O  OG1  . THR A 1 219 ? 3.23700   -5.08800  8.79700  1.000 11.73506 ? 242 THR A OG1  1 
ATOM   3459 C  CG2  . THR A 1 219 ? 1.67000   -6.58100  9.83300  1.000 11.92494 ? 242 THR A CG2  1 
ATOM   3460 H  H    . THR A 1 219 ? 1.70400   -4.07700  6.83600  1.000 13.86429 ? 242 THR A H    1 
ATOM   3461 H  HA   . THR A 1 219 ? 2.02700   -6.67600  7.20600  1.000 12.33433 ? 242 THR A HA   1 
ATOM   3462 H  HB   . THR A 1 219 ? 1.31600   -4.71100  9.09600  1.000 12.58388 ? 242 THR A HB   1 
ATOM   3463 H  HG1  . THR A 1 219 ? 3.32800   -4.36700  8.37600  1.000 14.08012 ? 242 THR A HG1  1 
ATOM   3464 H  HG21 . THR A 1 219 ? 2.12100   -6.35900  10.66200 1.000 14.30798 ? 242 THR A HG21 1 
ATOM   3465 H  HG22 . THR A 1 219 ? 0.72500   -6.70800  10.01400 1.000 14.30798 ? 242 THR A HG22 1 
ATOM   3466 H  HG23 . THR A 1 219 ? 2.03700   -7.40900  9.48600  1.000 14.30798 ? 242 THR A HG23 1 
ATOM   3467 N  N    . THR A 1 220 ? -0.15600  -7.74600  7.27900  1.000 10.20751 ? 243 THR A N    1 
ATOM   3468 C  CA   . THR A 1 220 ? -1.45100  -8.38800  7.09100  1.000 10.11434 ? 243 THR A CA   1 
ATOM   3469 C  C    . THR A 1 220 ? -1.41200  -9.66400  7.91800  1.000 9.66136  ? 243 THR A C    1 
ATOM   3470 O  O    . THR A 1 220 ? -0.62100  -10.56800 7.62200  1.000 10.23103 ? 243 THR A O    1 
ATOM   3471 C  CB   . THR A 1 220 ? -1.68000  -8.71300  5.60900  1.000 11.38313 ? 243 THR A CB   1 
ATOM   3472 O  OG1  . THR A 1 220 ? -1.35300  -7.58400  4.79000  1.000 11.83658 ? 243 THR A OG1  1 
ATOM   3473 C  CG2  . THR A 1 220 ? -3.11300  -9.06300  5.37000  1.000 13.04017 ? 243 THR A CG2  1 
ATOM   3474 H  H    . THR A 1 220 ? 0.49600   -8.30700  7.30000  1.000 12.24706 ? 243 THR A H    1 
ATOM   3475 H  HA   . THR A 1 220 ? -2.17300  -7.81700  7.39600  1.000 12.13526 ? 243 THR A HA   1 
ATOM   3476 H  HB   . THR A 1 220 ? -1.11500  -9.46400  5.36700  1.000 13.65780 ? 243 THR A HB   1 
ATOM   3477 H  HG1  . THR A 1 220 ? -0.53400  -7.41000  4.85500  1.000 14.20195 ? 243 THR A HG1  1 
ATOM   3478 H  HG21 . THR A 1 220 ? -3.25300  -9.26700  4.43200  1.000 15.64625 ? 243 THR A HG21 1 
ATOM   3479 H  HG22 . THR A 1 220 ? -3.35900  -9.83700  5.90000  1.000 15.64625 ? 243 THR A HG22 1 
ATOM   3480 H  HG23 . THR A 1 220 ? -3.68200  -8.31800  5.61800  1.000 15.64625 ? 243 THR A HG23 1 
ATOM   3481 N  N    . ASN A 1 221 ? -2.25600  -9.73400  8.94300  1.000 9.27926  ? 244 ASN A N    1 
ATOM   3482 C  CA   . ASN A 1 221 ? -2.20100  -10.79300 9.94000  1.000 9.47003  ? 244 ASN A CA   1 
ATOM   3483 C  C    . ASN A 1 221 ? -3.58500  -11.37900 10.19100 1.000 9.00043  ? 244 ASN A C    1 
ATOM   3484 O  O    . ASN A 1 221 ? -4.61100  -10.73300 9.98600  1.000 9.19038  ? 244 ASN A O    1 
ATOM   3485 C  CB   . ASN A 1 221 ? -1.71800  -10.21900 11.28100 1.000 9.96438  ? 244 ASN A CB   1 
ATOM   3486 C  CG   . ASN A 1 221 ? -0.31400  -9.66300  11.22800 1.000 9.69008  ? 244 ASN A CG   1 
ATOM   3487 O  OD1  . ASN A 1 221 ? 0.52100   -10.07900 10.42900 1.000 10.40901 ? 244 ASN A OD1  1 
ATOM   3488 N  ND2  . ASN A 1 221 ? -0.03700  -8.72700  12.13700 1.000 10.25950 ? 244 ASN A ND2  1 
ATOM   3489 H  H    . ASN A 1 221 ? -2.88500  -9.16400  9.08500  1.000 11.13316 ? 244 ASN A H    1 
ATOM   3490 H  HA   . ASN A 1 221 ? -1.61700  -11.49400 9.61200  1.000 11.36209 ? 244 ASN A HA   1 
ATOM   3491 H  HB2  . ASN A 1 221 ? -2.31200  -9.49900  11.54500 1.000 11.95531 ? 244 ASN A HB2  1 
ATOM   3492 H  HB3  . ASN A 1 221 ? -1.73400  -10.92400 11.94700 1.000 11.95531 ? 244 ASN A HB3  1 
ATOM   3493 H  HD21 . ASN A 1 221 ? 0.74500   -8.36900  12.16100 1.000 12.30945 ? 244 ASN A HD21 1 
ATOM   3494 H  HD22 . ASN A 1 221 ? -0.64000  -8.48100  12.69800 1.000 12.30945 ? 244 ASN A HD22 1 
ATOM   3495 N  N    . ASP A 1 222 ? -3.60600  -12.59000 10.74700 1.000 9.38445  ? 245 ASP A N    1 
ATOM   3496 C  CA   . ASP A 1 222 ? -4.85300  -13.18100 11.22600 1.000 9.14313  ? 245 ASP A CA   1 
ATOM   3497 C  C    . ASP A 1 222 ? -4.48000  -14.26400 12.22400 1.000 8.53586  ? 245 ASP A C    1 
ATOM   3498 O  O    . ASP A 1 222 ? -3.49500  -14.98200 12.03100 1.000 9.20441  ? 245 ASP A O    1 
ATOM   3499 C  CB   . ASP A 1 222 ? -5.64100  -13.78800 10.04700 1.000 9.31374  ? 245 ASP A CB   1 
ATOM   3500 C  CG   . ASP A 1 222 ? -7.12200  -14.01300 10.33400 1.000 9.47965  ? 245 ASP A CG   1 
ATOM   3501 O  OD1  . ASP A 1 222 ? -7.66600  -13.47000 11.33900 1.000 10.01219 ? 245 ASP A OD1  1 
ATOM   3502 O  OD2  . ASP A 1 222 ? -7.73600  -14.73900 9.51700  1.000 9.88286  ? 245 ASP A OD2  1 
ATOM   3503 H  H    . ASP A 1 222 ? -2.91400  -13.08800 10.85700 1.000 11.25940 ? 245 ASP A H    1 
ATOM   3504 H  HA   . ASP A 1 222 ? -5.41200  -12.52100 11.66600 1.000 10.96981 ? 245 ASP A HA   1 
ATOM   3505 H  HB2  . ASP A 1 222 ? -5.57700  -13.18700 9.28800  1.000 11.17454 ? 245 ASP A HB2  1 
ATOM   3506 H  HB3  . ASP A 1 222 ? -5.25200  -14.64800 9.82300  1.000 11.17454 ? 245 ASP A HB3  1 
ATOM   3507 N  N    . ILE A 1 223 ? -5.26800  -14.37200 13.28800 1.000 8.67613  ? 246 ILE A N    1 
ATOM   3508 C  CA   . ILE A 1 223 ? -5.12800  -15.43800 14.28000 1.000 8.86608  ? 246 ILE A CA   1 
ATOM   3509 C  C    . ILE A 1 223 ? -6.49600  -16.07000 14.46500 1.000 9.23163  ? 246 ILE A C    1 
ATOM   3510 O  O    . ILE A 1 223 ? -7.50100  -15.35700 14.53700 1.000 9.44871  ? 246 ILE A O    1 
ATOM   3511 C  CB   . ILE A 1 223 ? -4.48400  -14.94500 15.59500 1.000 9.25005  ? 246 ILE A CB   1 
ATOM   3512 C  CG1  . ILE A 1 223 ? -5.39700  -14.03600 16.44200 1.000 10.12702 ? 246 ILE A CG1  1 
ATOM   3513 C  CG2  . ILE A 1 223 ? -3.16300  -14.24400 15.28300 1.000 8.97992  ? 246 ILE A CG2  1 
ATOM   3514 C  CD1  . ILE A 1 223 ? -4.77000  -13.67000 17.77800 1.000 10.85179 ? 246 ILE A CD1  1 
ATOM   3515 H  H    . ILE A 1 223 ? -5.90900  -13.82600 13.46300 1.000 10.40940 ? 246 ILE A H    1 
ATOM   3516 H  HA   . ILE A 1 223 ? -4.53300  -16.13100 13.95400 1.000 10.63735 ? 246 ILE A HA   1 
ATOM   3517 H  HB   . ILE A 1 223 ? -4.33100  -15.73400 16.13800 1.000 11.09811 ? 246 ILE A HB   1 
ATOM   3518 H  HG12 . ILE A 1 223 ? -5.56900  -13.21600 15.95400 1.000 12.15047 ? 246 ILE A HG12 1 
ATOM   3519 H  HG13 . ILE A 1 223 ? -6.23100  -14.49900 16.61700 1.000 12.15047 ? 246 ILE A HG13 1 
ATOM   3520 H  HG21 . ILE A 1 223 ? -2.64000  -14.17800 16.09800 1.000 10.77395 ? 246 ILE A HG21 1 
ATOM   3521 H  HG22 . ILE A 1 223 ? -2.67900  -14.76200 14.62100 1.000 10.77395 ? 246 ILE A HG22 1 
ATOM   3522 H  HG23 . ILE A 1 223 ? -3.35000  -13.35700 14.93700 1.000 10.77395 ? 246 ILE A HG23 1 
ATOM   3523 H  HD11 . ILE A 1 223 ? -5.42000  -13.18100 18.30800 1.000 13.02020 ? 246 ILE A HD11 1 
ATOM   3524 H  HD12 . ILE A 1 223 ? -4.51100  -14.48300 18.23900 1.000 13.02020 ? 246 ILE A HD12 1 
ATOM   3525 H  HD13 . ILE A 1 223 ? -3.99000  -13.11600 17.61900 1.000 13.02020 ? 246 ILE A HD13 1 
ATOM   3526 N  N    . ALA A 1 224 ? -6.55100  -17.40600 14.51000 1.000 8.70143  ? 247 ALA A N    1 
ATOM   3527 C  CA   . ALA A 1 224 ? -7.83700  -18.07900 14.48100 1.000 9.62124  ? 247 ALA A CA   1 
ATOM   3528 C  C    . ALA A 1 224 ? -7.85900  -19.33900 15.32600 1.000 8.87308  ? 247 ALA A C    1 
ATOM   3529 O  O    . ALA A 1 224 ? -6.86700  -20.07400 15.42400 1.000 9.59864  ? 247 ALA A O    1 
ATOM   3530 C  CB   . ALA A 1 224 ? -8.20300  -18.49400 13.05900 1.000 10.59542 ? 247 ALA A CB   1 
ATOM   3531 H  H    . ALA A 1 224 ? -5.86800  -17.92600 14.55700 1.000 10.43977 ? 247 ALA A H    1 
ATOM   3532 H  HA   . ALA A 1 224 ? -8.48300  -17.46000 14.85600 1.000 11.54354 ? 247 ALA A HA   1 
ATOM   3533 H  HB1  . ALA A 1 224 ? -9.05900  -18.95200 13.07500 1.000 12.71256 ? 247 ALA A HB1  1 
ATOM   3534 H  HB2  . ALA A 1 224 ? -8.26300  -17.70100 12.50400 1.000 12.71256 ? 247 ALA A HB2  1 
ATOM   3535 H  HB3  . ALA A 1 224 ? -7.51700  -19.08700 12.71700 1.000 12.71256 ? 247 ALA A HB3  1 
ATOM   3536 N  N    . VAL A 1 225 ? -9.04200  -19.60300 15.87400 1.000 10.00568 ? 248 VAL A N    1 
ATOM   3537 C  CA   . VAL A 1 225 ? -9.43200  -20.92500 16.35500 1.000 9.70304  ? 248 VAL A CA   1 
ATOM   3538 C  C    . VAL A 1 225 ? -10.41000 -21.49100 15.33300 1.000 10.02320 ? 248 VAL A C    1 
ATOM   3539 O  O    . VAL A 1 225 ? -11.30200 -20.78300 14.86100 1.000 11.02457 ? 248 VAL A O    1 
ATOM   3540 C  CB   . VAL A 1 225 ? -9.98800  -20.88000 17.79300 1.000 10.67390 ? 248 VAL A CB   1 
ATOM   3541 C  CG1  . VAL A 1 225 ? -11.14000 -19.87800 17.95000 1.000 12.67206 ? 248 VAL A CG1  1 
ATOM   3542 C  CG2  . VAL A 1 225 ? -10.38100 -22.27900 18.27100 1.000 11.39472 ? 248 VAL A CG2  1 
ATOM   3543 H  H    . VAL A 1 225 ? -9.65700  -19.01100 15.98100 1.000 12.00486 ? 248 VAL A H    1 
ATOM   3544 H  HA   . VAL A 1 225 ? -8.66700  -21.52000 16.39500 1.000 11.64170 ? 248 VAL A HA   1 
ATOM   3545 H  HB   . VAL A 1 225 ? -9.27800  -20.55900 18.37100 1.000 12.80672 ? 248 VAL A HB   1 
ATOM   3546 H  HG11 . VAL A 1 225 ? -11.44900 -19.89400 18.87000 1.000 15.20452 ? 248 VAL A HG11 1 
ATOM   3547 H  HG12 . VAL A 1 225 ? -10.81900 -18.99100 17.72500 1.000 15.20452 ? 248 VAL A HG12 1 
ATOM   3548 H  HG13 . VAL A 1 225 ? -11.86200 -20.13100 17.35400 1.000 15.20452 ? 248 VAL A HG13 1 
ATOM   3549 H  HG21 . VAL A 1 225 ? -10.63100 -22.23400 19.20700 1.000 13.67171 ? 248 VAL A HG21 1 
ATOM   3550 H  HG22 . VAL A 1 225 ? -11.13100 -22.59400 17.74300 1.000 13.67171 ? 248 VAL A HG22 1 
ATOM   3551 H  HG23 . VAL A 1 225 ? -9.62400  -22.87500 18.15900 1.000 13.67171 ? 248 VAL A HG23 1 
ATOM   3552 N  N    . ILE A 1 226 ? -10.21400 -22.75600 14.96100 1.000 10.51114 ? 249 ILE A N    1 
ATOM   3553 C  CA   . ILE A 1 226 ? -10.90400 -23.36700 13.83800 1.000 11.10687 ? 249 ILE A CA   1 
ATOM   3554 C  C    . ILE A 1 226 ? -11.50300 -24.68700 14.28700 1.000 11.99353 ? 249 ILE A C    1 
ATOM   3555 O  O    . ILE A 1 226 ? -10.80600 -25.52600 14.86500 1.000 12.62456 ? 249 ILE A O    1 
ATOM   3556 C  CB   . ILE A 1 226 ? -9.92800  -23.62100 12.67600 1.000 11.77406 ? 249 ILE A CB   1 
ATOM   3557 C  CG1  . ILE A 1 226 ? -9.26500  -22.32900 12.20600 1.000 12.06727 ? 249 ILE A CG1  1 
ATOM   3558 C  CG2  . ILE A 1 226 ? -10.65200 -24.31300 11.52000 1.000 12.79972 ? 249 ILE A CG2  1 
ATOM   3559 C  CD1  . ILE A 1 226 ? -8.00600  -22.57400 11.42800 1.000 13.33919 ? 249 ILE A CD1  1 
ATOM   3560 H  H    . ILE A 1 226 ? -9.67100  -23.29100 15.35900 1.000 12.61141 ? 249 ILE A H    1 
ATOM   3561 H  HA   . ILE A 1 226 ? -11.62400 -22.78400 13.54800 1.000 13.32629 ? 249 ILE A HA   1 
ATOM   3562 H  HB   . ILE A 1 226 ? -9.22500  -24.20500 13.00100 1.000 14.12692 ? 249 ILE A HB   1 
ATOM   3563 H  HG12 . ILE A 1 226 ? -9.88300  -21.84600 11.63500 1.000 14.47878 ? 249 ILE A HG12 1 
ATOM   3564 H  HG13 . ILE A 1 226 ? -9.03900  -21.79000 12.98100 1.000 14.47878 ? 249 ILE A HG13 1 
ATOM   3565 H  HG21 . ILE A 1 226 ? -10.08200 -24.29500 10.73500 1.000 15.35771 ? 249 ILE A HG21 1 
ATOM   3566 H  HG22 . ILE A 1 226 ? -10.84100 -25.23100 11.77000 1.000 15.35771 ? 249 ILE A HG22 1 
ATOM   3567 H  HG23 . ILE A 1 226 ? -11.48000 -23.84200 11.33900 1.000 15.35771 ? 249 ILE A HG23 1 
ATOM   3568 H  HD11 . ILE A 1 226 ? -7.64700  -21.72300 11.13100 1.000 16.00508 ? 249 ILE A HD11 1 
ATOM   3569 H  HD12 . ILE A 1 226 ? -7.36300  -23.02300 11.99900 1.000 16.00508 ? 249 ILE A HD12 1 
ATOM   3570 H  HD13 . ILE A 1 226 ? -8.21200  -23.13100 10.66100 1.000 16.00508 ? 249 ILE A HD13 1 
ATOM   3571 N  N    . TRP A 1 227 ? -12.77700 -24.89600 13.96100 1.000 12.43317 ? 250 TRP A N    1 
ATOM   3572 C  CA   . TRP A 1 227 ? -13.45500 -26.16600 14.19400 1.000 13.91259 ? 250 TRP A CA   1 
ATOM   3573 C  C    . TRP A 1 227 ? -13.73300 -26.78200 12.83700 1.000 14.64138 ? 250 TRP A C    1 
ATOM   3574 O  O    . TRP A 1 227 ? -14.73800 -26.44800 12.18300 1.000 15.67505 ? 250 TRP A O    1 
ATOM   3575 C  CB   . TRP A 1 227 ? -14.74500 -25.96800 14.97800 1.000 15.60737 ? 250 TRP A CB   1 
ATOM   3576 C  CG   . TRP A 1 227 ? -14.47000 -25.58100 16.37800 1.000 18.82327 ? 250 TRP A CG   1 
ATOM   3577 C  CD1  . TRP A 1 227 ? -14.28900 -26.41800 17.43500 1.000 19.57085 ? 250 TRP A CD1  1 
ATOM   3578 C  CD2  . TRP A 1 227 ? -14.32700 -24.25500 16.88300 1.000 19.49575 ? 250 TRP A CD2  1 
ATOM   3579 N  NE1  . TRP A 1 227 ? -14.05100 -25.69300 18.58000 1.000 21.64012 ? 250 TRP A NE1  1 
ATOM   3580 C  CE2  . TRP A 1 227 ? -14.06900 -24.36000 18.26500 1.000 20.76461 ? 250 TRP A CE2  1 
ATOM   3581 C  CE3  . TRP A 1 227 ? -14.39400 -22.98500 16.30300 1.000 19.98559 ? 250 TRP A CE3  1 
ATOM   3582 C  CZ2  . TRP A 1 227 ? -13.88300 -23.24200 19.07500 1.000 21.58495 ? 250 TRP A CZ2  1 
ATOM   3583 C  CZ3  . TRP A 1 227 ? -14.21300 -21.87800 17.10600 1.000 20.51304 ? 250 TRP A CZ3  1 
ATOM   3584 C  CH2  . TRP A 1 227 ? -13.96000 -22.01200 18.47700 1.000 21.30339 ? 250 TRP A CH2  1 
ATOM   3585 H  H    . TRP A 1 227 ? -13.28000 -24.30100 13.59500 1.000 14.91785 ? 250 TRP A H    1 
ATOM   3586 H  HA   . TRP A 1 227 ? -12.88800 -26.75700 14.71300 1.000 16.69316 ? 250 TRP A HA   1 
ATOM   3587 H  HB2  . TRP A 1 227 ? -15.26800 -25.26400 14.56300 1.000 18.72689 ? 250 TRP A HB2  1 
ATOM   3588 H  HB3  . TRP A 1 227 ? -15.24800 -26.79700 14.98300 1.000 18.72689 ? 250 TRP A HB3  1 
ATOM   3589 H  HD1  . TRP A 1 227 ? -14.32100 -27.34700 17.39000 1.000 23.48307 ? 250 TRP A HD1  1 
ATOM   3590 H  HE1  . TRP A 1 227 ? -13.91400 -26.02200 19.36200 1.000 25.96619 ? 250 TRP A HE1  1 
ATOM   3591 H  HE3  . TRP A 1 227 ? -14.55800 -22.88700 15.39300 1.000 23.98076 ? 250 TRP A HE3  1 
ATOM   3592 H  HZ2  . TRP A 1 227 ? -13.71400 -23.32700 19.98500 1.000 25.89999 ? 250 TRP A HZ2  1 
ATOM   3593 H  HZ3  . TRP A 1 227 ? -14.26100 -21.02800 16.73100 1.000 24.61370 ? 250 TRP A HZ3  1 
ATOM   3594 H  HH2  . TRP A 1 227 ? -13.84000 -21.24800 18.99300 1.000 25.56212 ? 250 TRP A HH2  1 
ATOM   3595 N  N    . PRO A 1 228 ? -12.85300 -27.64400 12.34400 1.000 14.92378 ? 251 PRO A N    1 
ATOM   3596 C  CA   . PRO A 1 228 ? -13.11800 -28.30100 11.07100 1.000 15.88374 ? 251 PRO A CA   1 
ATOM   3597 C  C    . PRO A 1 228 ? -14.26400 -29.27700 11.23900 1.000 16.94399 ? 251 PRO A C    1 
ATOM   3598 O  O    . PRO A 1 228 ? -14.55700 -29.75200 12.34000 1.000 17.40632 ? 251 PRO A O    1 
ATOM   3599 C  CB   . PRO A 1 228 ? -11.80600 -29.03500 10.77000 1.000 16.22036 ? 251 PRO A CB   1 
ATOM   3600 C  CG   . PRO A 1 228 ? -10.81800 -28.56500 11.76600 1.000 16.13873 ? 251 PRO A CG   1 
ATOM   3601 C  CD   . PRO A 1 228 ? -11.60500 -28.13900 12.94800 1.000 15.56295 ? 251 PRO A CD   1 
ATOM   3602 H  HA   . PRO A 1 228 ? -13.29900 -27.66800 10.35800 1.000 19.05854 ? 251 PRO A HA   1 
ATOM   3603 H  HB2  . PRO A 1 228 ? -11.94500 -29.99200 10.85200 1.000 19.46248 ? 251 PRO A HB2  1 
ATOM   3604 H  HB3  . PRO A 1 228 ? -11.51300 -28.81900 9.87000  1.000 19.46248 ? 251 PRO A HB3  1 
ATOM   3605 H  HG2  . PRO A 1 228 ? -10.21600 -29.28900 11.99800 1.000 19.36453 ? 251 PRO A HG2  1 
ATOM   3606 H  HG3  . PRO A 1 228 ? -10.31500 -27.81900 11.40200 1.000 19.36453 ? 251 PRO A HG3  1 
ATOM   3607 H  HD2  . PRO A 1 228 ? -11.77900 -28.88900 13.53800 1.000 18.67359 ? 251 PRO A HD2  1 
ATOM   3608 H  HD3  . PRO A 1 228 ? -11.15000 -27.43300 13.43300 1.000 18.67359 ? 251 PRO A HD3  1 
ATOM   3609 N  N    . LYS A 1 229 ? -14.92500 -29.57400 10.13300 1.000 18.46266 ? 252 LYS A N    1 
ATOM   3610 C  CA   . LYS A 1 229 ? -16.05100 -30.49400 10.19300 1.000 20.11624 ? 252 LYS A CA   1 
ATOM   3611 C  C    . LYS A 1 229 ? -15.59200 -31.84800 10.72200 1.000 19.68811 ? 252 LYS A C    1 
ATOM   3612 O  O    . LYS A 1 229 ? -14.68700 -32.46500 10.15700 1.000 21.31046 ? 252 LYS A O    1 
ATOM   3613 C  CB   . LYS A 1 229 ? -16.67700 -30.65300 8.80700  1.000 23.37821 ? 252 LYS A CB   1 
ATOM   3614 C  CG   . LYS A 1 229 ? -17.90500 -31.56100 8.80500  1.000 27.22767 ? 252 LYS A CG   1 
ATOM   3615 C  CD   . LYS A 1 229 ? -18.56000 -31.66000 7.42500  1.000 31.83223 ? 252 LYS A CD   1 
ATOM   3616 C  CE   . LYS A 1 229 ? -19.79800 -32.56000 7.45900  1.000 35.64896 ? 252 LYS A CE   1 
ATOM   3617 N  NZ   . LYS A 1 229 ? -20.41300 -32.76000 6.11600  1.000 38.31531 ? 252 LYS A NZ   1 
ATOM   3618 H  H    . LYS A 1 229 ? -14.74700 -29.26300 9.35100  1.000 22.15324 ? 252 LYS A H    1 
ATOM   3619 H  HA   . LYS A 1 229 ? -16.72600 -30.13600 10.79200 1.000 24.13754 ? 252 LYS A HA   1 
ATOM   3620 H  HB2  . LYS A 1 229 ? -16.94900 -29.78000 8.48300  1.000 28.05191 ? 252 LYS A HB2  1 
ATOM   3621 H  HB3  . LYS A 1 229 ? -16.01900 -31.03900 8.20700  1.000 28.05191 ? 252 LYS A HB3  1 
ATOM   3622 H  HG2  . LYS A 1 229 ? -17.64100 -32.45400 9.07700  1.000 32.67125 ? 252 LYS A HG2  1 
ATOM   3623 H  HG3  . LYS A 1 229 ? -18.56200 -31.20700 9.42400  1.000 32.67125 ? 252 LYS A HG3  1 
ATOM   3624 H  HD2  . LYS A 1 229 ? -18.83200 -30.77600 7.13400  1.000 38.19673 ? 252 LYS A HD2  1 
ATOM   3625 H  HD3  . LYS A 1 229 ? -17.92600 -32.03600 6.79500  1.000 38.19673 ? 252 LYS A HD3  1 
ATOM   3626 H  HE2  . LYS A 1 229 ? -19.54500 -33.43100 7.80300  1.000 42.77681 ? 252 LYS A HE2  1 
ATOM   3627 H  HE3  . LYS A 1 229 ? -20.46500 -32.15600 8.03500  1.000 42.77681 ? 252 LYS A HE3  1 
ATOM   3628 H  HZ1  . LYS A 1 229 ? -21.13800 -33.27100 6.18700  1.000 45.97643 ? 252 LYS A HZ1  1 
ATOM   3629 H  HZ2  . LYS A 1 229 ? -20.64700 -31.97500 5.76800  1.000 45.97643 ? 252 LYS A HZ2  1 
ATOM   3630 H  HZ3  . LYS A 1 229 ? -19.83200 -33.15600 5.57100  1.000 45.97643 ? 252 LYS A HZ3  1 
ATOM   3631 N  N    . ASP A 1 230 ? -16.20600 -32.28500 11.82600 1.000 19.29682 ? 253 ASP A N    1 
ATOM   3632 C  CA   . ASP A 1 230 ? -15.96500 -33.59700 12.44300 1.000 19.96067 ? 253 ASP A CA   1 
ATOM   3633 C  C    . ASP A 1 230 ? -14.50400 -33.84800 12.81600 1.000 18.64000 ? 253 ASP A C    1 
ATOM   3634 O  O    . ASP A 1 230 ? -14.03200 -34.98800 12.76300 1.000 20.62799 ? 253 ASP A O    1 
ATOM   3635 C  CB   . ASP A 1 230 ? -16.51200 -34.73700 11.58300 1.000 22.30780 ? 253 ASP A CB   1 
ATOM   3636 C  CG   . ASP A 1 230 ? -18.01000 -34.66100 11.42300 1.000 25.62007 ? 253 ASP A CG   1 
ATOM   3637 O  OD1  . ASP A 1 230 ? -18.70000 -34.40300 12.43300 1.000 26.64115 ? 253 ASP A OD1  1 
ATOM   3638 O  OD2  . ASP A 1 230 ? -18.48500 -34.83900 10.28900 1.000 27.82056 ? 253 ASP A OD2  1 
ATOM   3639 H  H    . ASP A 1 230 ? -16.79100 -31.82300 12.25400 1.000 23.15423 ? 253 ASP A H    1 
ATOM   3640 H  HA   . ASP A 1 230 ? -16.44900 -33.59600 13.28300 1.000 23.95086 ? 253 ASP A HA   1 
ATOM   3641 H  HB2  . ASP A 1 230 ? -16.11100 -34.69000 10.70100 1.000 26.76741 ? 253 ASP A HB2  1 
ATOM   3642 H  HB3  . ASP A 1 230 ? -16.29500 -35.58400 12.00100 1.000 26.76741 ? 253 ASP A HB3  1 
ATOM   3643 N  N    A ARG A 1 231 ? -13.78200 -32.80200 13.21100 0.485 17.36870 ? 254 ARG A N    1 
ATOM   3644 N  N    B ARG A 1 231 ? -13.78800 -32.80500 13.22500 0.515 16.68017 ? 254 ARG A N    1 
ATOM   3645 C  CA   A ARG A 1 231 ? -12.38700 -32.94000 13.60200 0.485 17.25217 ? 254 ARG A CA   1 
ATOM   3646 C  CA   B ARG A 1 231 ? -12.39000 -32.93800 13.60500 0.515 16.36574 ? 254 ARG A CA   1 
ATOM   3647 C  C    A ARG A 1 231 ? -12.12600 -32.14800 14.87700 0.485 15.12347 ? 254 ARG A C    1 
ATOM   3648 C  C    B ARG A 1 231 ? -12.12200 -32.14300 14.87500 0.515 14.27705 ? 254 ARG A C    1 
ATOM   3649 O  O    A ARG A 1 231 ? -12.86400 -31.22100 15.22500 0.485 15.69542 ? 254 ARG A O    1 
ATOM   3650 O  O    B ARG A 1 231 ? -12.84500 -31.19900 15.21200 0.515 14.37296 ? 254 ARG A O    1 
ATOM   3651 C  CB   A ARG A 1 231 ? -11.42300 -32.42700 12.52000 0.485 19.71262 ? 254 ARG A CB   1 
ATOM   3652 C  CB   B ARG A 1 231 ? -11.44400 -32.41600 12.51300 0.515 18.56550 ? 254 ARG A CB   1 
ATOM   3653 C  CG   A ARG A 1 231 ? -11.47300 -33.16900 11.18200 0.485 22.60388 ? 254 ARG A CG   1 
ATOM   3654 C  CG   B ARG A 1 231 ? -11.47600 -33.18100 11.18500 0.515 21.64256 ? 254 ARG A CG   1 
ATOM   3655 C  CD   A ARG A 1 231 ? -10.46300 -32.56500 10.19500 0.485 25.81353 ? 254 ARG A CD   1 
ATOM   3656 C  CD   B ARG A 1 231 ? -10.61600 -32.47200 10.12200 0.515 25.35698 ? 254 ARG A CD   1 
ATOM   3657 N  NE   A ARG A 1 231 ? -10.38400 -33.27700 8.92400  0.485 28.81582 ? 254 ARG A NE   1 
ATOM   3658 N  NE   B ARG A 1 231 ? -10.54700 -33.18100 8.84800  0.515 28.39071 ? 254 ARG A NE   1 
ATOM   3659 C  CZ   A ARG A 1 231 ? -9.60500  -34.32900 8.70000  0.485 30.74497 ? 254 ARG A CZ   1 
ATOM   3660 C  CZ   B ARG A 1 231 ? -11.42300 -33.05300 7.85900  0.515 30.74623 ? 254 ARG A CZ   1 
ATOM   3661 N  NH1  A ARG A 1 231 ? -8.84500  -34.84300 9.65400  0.485 30.95004 ? 254 ARG A NH1  1 
ATOM   3662 N  NH1  B ARG A 1 231 ? -12.47000 -32.25000 7.96100  0.515 31.21956 ? 254 ARG A NH1  1 
ATOM   3663 N  NH2  A ARG A 1 231 ? -9.58900  -34.87800 7.48800  0.485 31.83298 ? 254 ARG A NH2  1 
ATOM   3664 N  NH2  B ARG A 1 231 ? -11.24700 -33.75200 6.74100  0.515 32.06711 ? 254 ARG A NH2  1 
ATOM   3665 H  H    A ARG A 1 231 ? -14.08200 -31.99800 13.26100 0.485 20.84049 ? 254 ARG A H    1 
ATOM   3666 H  H    B ARG A 1 231 ? -14.09400 -32.00400 13.29100 0.515 20.01425 ? 254 ARG A H    1 
ATOM   3667 H  HA   A ARG A 1 231 ? -12.21900 -33.88100 13.76500 0.485 20.70065 ? 254 ARG A HA   1 
ATOM   3668 H  HA   B ARG A 1 231 ? -12.21400 -33.87800 13.76700 0.515 19.63694 ? 254 ARG A HA   1 
ATOM   3669 H  HB2  A ARG A 1 231 ? -11.63300 -31.49700 12.34200 0.485 23.65319 ? 254 ARG A HB2  1 
ATOM   3670 H  HB2  B ARG A 1 231 ? -11.67900 -31.49500 12.32100 0.515 22.27665 ? 254 ARG A HB2  1 
ATOM   3671 H  HB3  A ARG A 1 231 ? -10.51800 -32.50400 12.85800 0.485 23.65319 ? 254 ARG A HB3  1 
ATOM   3672 H  HB3  B ARG A 1 231 ? -10.53500 -32.46200 12.85000 0.515 22.27665 ? 254 ARG A HB3  1 
ATOM   3673 H  HG2  A ARG A 1 231 ? -11.25000 -34.10300 11.31900 0.485 27.12271 ? 254 ARG A HG2  1 
ATOM   3674 H  HG2  B ARG A 1 231 ? -11.12500 -34.07500 11.31800 0.515 25.96912 ? 254 ARG A HG2  1 
ATOM   3675 H  HG3  A ARG A 1 231 ? -12.36100 -33.09300 10.80100 0.485 27.12271 ? 254 ARG A HG3  1 
ATOM   3676 H  HG3  B ARG A 1 231 ? -12.38900 -33.22700 10.86000 0.515 25.96912 ? 254 ARG A HG3  1 
ATOM   3677 H  HD2  A ARG A 1 231 ? -10.72200 -31.65000 10.00500 0.485 30.97428 ? 254 ARG A HD2  1 
ATOM   3678 H  HD2  B ARG A 1 231 ? -10.99100 -31.59400 9.95200  0.515 30.42643 ? 254 ARG A HD2  1 
ATOM   3679 H  HD3  A ARG A 1 231 ? -9.58200  -32.58300 10.60000 0.485 30.97428 ? 254 ARG A HD3  1 
ATOM   3680 H  HD3  B ARG A 1 231 ? -9.71100  -32.38600 10.46100 0.515 30.42643 ? 254 ARG A HD3  1 
ATOM   3681 H  HE   A ARG A 1 231 ? -10.87400 -32.99600 8.27600  0.485 34.57704 ? 254 ARG A HE   1 
ATOM   3682 H  HE   B ARG A 1 231 ? -9.88900  -33.72200 8.72800  0.515 34.06690 ? 254 ARG A HE   1 
ATOM   3683 H  HH11 A ARG A 1 231 ? -8.84700  -34.49600 10.44000 0.485 37.13810 ? 254 ARG A HH11 1 
ATOM   3684 H  HH11 B ARG A 1 231 ? -12.59500 -31.79600 8.68000  0.515 37.46152 ? 254 ARG A HH11 1 
ATOM   3685 H  HH12 A ARG A 1 231 ? -8.34800  -35.52500 9.48700  0.485 37.13810 ? 254 ARG A HH12 1 
ATOM   3686 H  HH12 B ARG A 1 231 ? -13.02500 -32.18300 7.30700  0.515 37.46152 ? 254 ARG A HH12 1 
ATOM   3687 H  HH21 A ARG A 1 231 ? -10.07800 -34.55100 6.86100  0.485 38.19762 ? 254 ARG A HH21 1 
ATOM   3688 H  HH21 B ARG A 1 231 ? -10.57100 -34.27900 6.66500  0.515 38.47859 ? 254 ARG A HH21 1 
ATOM   3689 H  HH22 A ARG A 1 231 ? -9.08800  -35.56000 7.33100  0.485 38.19762 ? 254 ARG A HH22 1 
ATOM   3690 H  HH22 B ARG A 1 231 ? -11.80800 -33.67800 6.09400  0.515 38.47859 ? 254 ARG A HH22 1 
ATOM   3691 N  N    . ALA A 1 232 ? -11.04200 -32.50900 15.55400 1.000 14.37802 ? 255 ALA A N    1 
ATOM   3692 C  CA   . ALA A 1 232 ? -10.59900 -31.73200 16.69700 1.000 12.92016 ? 255 ALA A CA   1 
ATOM   3693 C  C    . ALA A 1 232 ? -10.19500 -30.32900 16.23500 1.000 11.62599 ? 255 ALA A C    1 
ATOM   3694 O  O    . ALA A 1 232 ? -9.76700  -30.13500 15.09100 1.000 11.86163 ? 255 ALA A O    1 
ATOM   3695 C  CB   . ALA A 1 232 ? -9.40200  -32.40600 17.35700 1.000 14.41880 ? 255 ALA A CB   1 
ATOM   3696 H  H    . ALA A 1 232 ? -10.55600 -33.19500 15.37100 1.000 17.25168 ? 255 ALA A H    1 
ATOM   3697 H  HA   . ALA A 1 232 ? -11.31700 -31.66100 17.34600 1.000 15.50224 ? 255 ALA A HA   1 
ATOM   3698 H  HB1  . ALA A 1 232 ? -9.09200  -31.85200 18.09100 1.000 17.30061 ? 255 ALA A HB1  1 
ATOM   3699 H  HB2  . ALA A 1 232 ? -9.67300  -33.27500 17.69200 1.000 17.30061 ? 255 ALA A HB2  1 
ATOM   3700 H  HB3  . ALA A 1 232 ? -8.69600  -32.51000 16.70000 1.000 17.30061 ? 255 ALA A HB3  1 
ATOM   3701 N  N    . PRO A 1 233 ? -10.28600 -29.33800 17.10500 1.000 11.30397 ? 256 PRO A N    1 
ATOM   3702 C  CA   . PRO A 1 233 ? -9.98600  -27.97600 16.68000 1.000 11.15026 ? 256 PRO A CA   1 
ATOM   3703 C  C    . PRO A 1 233 ? -8.51600  -27.74400 16.36500 1.000 10.39238 ? 256 PRO A C    1 
ATOM   3704 O  O    . PRO A 1 233 ? -7.60700  -28.45800 16.80300 1.000 10.80684 ? 256 PRO A O    1 
ATOM   3705 C  CB   . PRO A 1 233 ? -10.43900 -27.10600 17.86200 1.000 14.81265 ? 256 PRO A CB   1 
ATOM   3706 C  CG   . PRO A 1 233 ? -10.73100 -27.99100 18.93400 1.000 17.44795 ? 256 PRO A CG   1 
ATOM   3707 C  CD   . PRO A 1 233 ? -10.91200 -29.37800 18.43900 1.000 13.34139 ? 256 PRO A CD   1 
ATOM   3708 H  HA   . PRO A 1 233 ? -10.51100 -27.76900 15.89100 1.000 13.37836 ? 256 PRO A HA   1 
ATOM   3709 H  HB2  . PRO A 1 233 ? -9.72500  -26.49800 18.10800 1.000 17.77323 ? 256 PRO A HB2  1 
ATOM   3710 H  HB3  . PRO A 1 233 ? -11.23000 -26.60400 17.61000 1.000 17.77323 ? 256 PRO A HB3  1 
ATOM   3711 H  HG2  . PRO A 1 233 ? -9.99300  -27.96400 19.56300 1.000 20.93559 ? 256 PRO A HG2  1 
ATOM   3712 H  HG3  . PRO A 1 233 ? -11.54600 -27.69100 19.36500 1.000 20.93559 ? 256 PRO A HG3  1 
ATOM   3713 H  HD2  . PRO A 1 233 ? -10.45900 -30.01300 19.01600 1.000 16.00772 ? 256 PRO A HD2  1 
ATOM   3714 H  HD3  . PRO A 1 233 ? -11.85400 -29.60200 18.37300 1.000 16.00772 ? 256 PRO A HD3  1 
ATOM   3715 N  N    . LEU A 1 234 ? -8.30000  -26.68800 15.59100 1.000 10.45275 ? 257 LEU A N    1 
ATOM   3716 C  CA   . LEU A 1 234 ? -6.98800  -26.18600 15.24200 1.000 10.46428 ? 257 LEU A CA   1 
ATOM   3717 C  C    . LEU A 1 234 ? -6.84100  -24.76200 15.74900 1.000 10.07181 ? 257 LEU A C    1 
ATOM   3718 O  O    . LEU A 1 234 ? -7.82500  -24.03700 15.90300 1.000 10.47800 ? 257 LEU A O    1 
ATOM   3719 C  CB   . LEU A 1 234 ? -6.82900  -26.10200 13.72200 1.000 11.60564 ? 257 LEU A CB   1 
ATOM   3720 C  CG   . LEU A 1 234 ? -7.25800  -27.31000 12.88700 1.000 12.40993 ? 257 LEU A CG   1 
ATOM   3721 C  CD1  . LEU A 1 234 ? -7.22800  -26.98400 11.39500 1.000 13.98406 ? 257 LEU A CD1  1 
ATOM   3722 C  CD2  . LEU A 1 234 ? -6.35000  -28.48100 13.20600 1.000 13.42910 ? 257 LEU A CD2  1 
ATOM   3723 H  H    . LEU A 1 234 ? -8.93400  -26.22500 15.24000 1.000 12.54135 ? 257 LEU A H    1 
ATOM   3724 H  HA   . LEU A 1 234 ? -6.31800  -26.76900 15.63400 1.000 12.55519 ? 257 LEU A HA   1 
ATOM   3725 H  HB2  . LEU A 1 234 ? -7.35600  -25.34900 13.41200 1.000 13.92481 ? 257 LEU A HB2  1 
ATOM   3726 H  HB3  . LEU A 1 234 ? -5.89000  -25.95100 13.53200 1.000 13.92481 ? 257 LEU A HB3  1 
ATOM   3727 H  HG   . LEU A 1 234 ? -8.17100  -27.55100 13.10600 1.000 14.88997 ? 257 LEU A HG   1 
ATOM   3728 H  HD11 . LEU A 1 234 ? -7.55500  -27.75100 10.89800 1.000 16.77892 ? 257 LEU A HD11 1 
ATOM   3729 H  HD12 . LEU A 1 234 ? -7.79500  -26.21500 11.22800 1.000 16.77892 ? 257 LEU A HD12 1 
ATOM   3730 H  HD13 . LEU A 1 234 ? -6.31600  -26.78500 11.13300 1.000 16.77892 ? 257 LEU A HD13 1 
ATOM   3731 H  HD21 . LEU A 1 234 ? -6.66200  -29.26300 12.72300 1.000 16.11297 ? 257 LEU A HD21 1 
ATOM   3732 H  HD22 . LEU A 1 234 ? -5.44500  -28.26300 12.93300 1.000 16.11297 ? 257 LEU A HD22 1 
ATOM   3733 H  HD23 . LEU A 1 234 ? -6.37700  -28.65000 14.16100 1.000 16.11297 ? 257 LEU A HD23 1 
ATOM   3734 N  N    . ILE A 1 235 ? -5.60000  -24.35800 15.96500 1.000 9.56375  ? 258 ILE A N    1 
ATOM   3735 C  CA   . ILE A 1 235 ? -5.23600  -22.96400 16.17400 1.000 9.77064  ? 258 ILE A CA   1 
ATOM   3736 C  C    . ILE A 1 235 ? -4.28300  -22.59300 15.05100 1.000 9.42799  ? 258 ILE A C    1 
ATOM   3737 O  O    . ILE A 1 235 ? -3.34400  -23.34000 14.77500 1.000 10.07960 ? 258 ILE A O    1 
ATOM   3738 C  CB   . ILE A 1 235 ? -4.56300  -22.75700 17.53800 1.000 10.31255 ? 258 ILE A CB   1 
ATOM   3739 C  CG1  . ILE A 1 235 ? -5.53300  -23.07900 18.67900 1.000 11.33346 ? 258 ILE A CG1  1 
ATOM   3740 C  CG2  . ILE A 1 235 ? -3.98900  -21.33700 17.65200 1.000 11.44543 ? 258 ILE A CG2  1 
ATOM   3741 C  CD1  . ILE A 1 235 ? -6.61600  -22.07500 18.87700 1.000 12.42985 ? 258 ILE A CD1  1 
ATOM   3742 H  H    . ILE A 1 235 ? -4.92600  -24.89100 15.99700 1.000 11.47455 ? 258 ILE A H    1 
ATOM   3743 H  HA   . ILE A 1 235 ? -6.02300  -22.39800 16.13800 1.000 11.72282 ? 258 ILE A HA   1 
ATOM   3744 H  HB   . ILE A 1 235 ? -3.82000  -23.37700 17.60900 1.000 12.37311 ? 258 ILE A HB   1 
ATOM   3745 H  HG12 . ILE A 1 235 ? -5.95600  -23.93200 18.49300 1.000 13.59820 ? 258 ILE A HG12 1 
ATOM   3746 H  HG13 . ILE A 1 235 ? -5.03000  -23.13300 19.50600 1.000 13.59820 ? 258 ILE A HG13 1 
ATOM   3747 H  HG21 . ILE A 1 235 ? -3.72500  -21.17700 18.57200 1.000 13.73257 ? 258 ILE A HG21 1 
ATOM   3748 H  HG22 . ILE A 1 235 ? -3.21900  -21.26000 17.06800 1.000 13.73257 ? 258 ILE A HG22 1 
ATOM   3749 H  HG23 . ILE A 1 235 ? -4.67000  -20.69900 17.38800 1.000 13.73257 ? 258 ILE A HG23 1 
ATOM   3750 H  HD11 . ILE A 1 235 ? -7.20900  -22.38300 19.58100 1.000 14.91387 ? 258 ILE A HD11 1 
ATOM   3751 H  HD12 . ILE A 1 235 ? -6.21800  -21.22700 19.12800 1.000 14.91387 ? 258 ILE A HD12 1 
ATOM   3752 H  HD13 . ILE A 1 235 ? -7.11100  -21.97600 18.04800 1.000 14.91387 ? 258 ILE A HD13 1 
ATOM   3753 N  N    . LEU A 1 236 ? -4.51600  -21.44800 14.40300 1.000 9.01629  ? 259 LEU A N    1 
ATOM   3754 C  CA   . LEU A 1 236 ? -3.64700  -21.02600 13.31400 1.000 9.16219  ? 259 LEU A CA   1 
ATOM   3755 C  C    . LEU A 1 236 ? -3.34000  -19.54200 13.44300 1.000 9.29720  ? 259 LEU A C    1 
ATOM   3756 O  O    . LEU A 1 236 ? -4.25300  -18.71300 13.53200 1.000 9.73548  ? 259 LEU A O    1 
ATOM   3757 C  CB   . LEU A 1 236 ? -4.31200  -21.27900 11.96100 1.000 9.90488  ? 259 LEU A CB   1 
ATOM   3758 C  CG   . LEU A 1 236 ? -3.53500  -20.85200 10.72000 1.000 10.22981 ? 259 LEU A CG   1 
ATOM   3759 C  CD1  . LEU A 1 236 ? -2.18600  -21.50300 10.65500 1.000 10.72621 ? 259 LEU A CD1  1 
ATOM   3760 C  CD2  . LEU A 1 236 ? -4.35100  -21.15900 9.47900  1.000 11.79169 ? 259 LEU A CD2  1 
ATOM   3761 H  H    . LEU A 1 236 ? -5.16400  -20.91000 14.57700 1.000 10.81760 ? 259 LEU A H    1 
ATOM   3762 H  HA   . LEU A 1 236 ? -2.81400  -21.51900 13.36700 1.000 10.99267 ? 259 LEU A HA   1 
ATOM   3763 H  HB2  . LEU A 1 236 ? -4.47300  -22.23200 11.88000 1.000 11.88391 ? 259 LEU A HB2  1 
ATOM   3764 H  HB3  . LEU A 1 236 ? -5.15400  -20.79700 11.94700 1.000 11.88391 ? 259 LEU A HB3  1 
ATOM   3765 H  HG   . LEU A 1 236 ? -3.37700  -19.89600 10.76100 1.000 12.27382 ? 259 LEU A HG   1 
ATOM   3766 H  HD11 . LEU A 1 236 ? -1.76700  -21.27700 9.81000  1.000 12.86951 ? 259 LEU A HD11 1 
ATOM   3767 H  HD12 . LEU A 1 236 ? -1.64400  -21.17800 11.39000 1.000 12.86951 ? 259 LEU A HD12 1 
ATOM   3768 H  HD13 . LEU A 1 236 ? -2.29600  -22.46400 10.72300 1.000 12.86951 ? 259 LEU A HD13 1 
ATOM   3769 H  HD21 . LEU A 1 236 ? -3.86200  -20.85700 8.69800  1.000 14.14807 ? 259 LEU A HD21 1 
ATOM   3770 H  HD22 . LEU A 1 236 ? -4.49800  -22.11700 9.42700  1.000 14.14807 ? 259 LEU A HD22 1 
ATOM   3771 H  HD23 . LEU A 1 236 ? -5.20100  -20.69600 9.53800  1.000 14.14807 ? 259 LEU A HD23 1 
ATOM   3772 N  N    . VAL A 1 237 ? -2.05200  -19.21500 13.38700 1.000 9.18087  ? 260 VAL A N    1 
ATOM   3773 C  CA   . VAL A 1 237 ? -1.56300  -17.85000 13.27900 1.000 9.16287  ? 260 VAL A CA   1 
ATOM   3774 C  C    . VAL A 1 237 ? -0.85900  -17.70700 11.94300 1.000 9.45880  ? 260 VAL A C    1 
ATOM   3775 O  O    . VAL A 1 237 ? 0.02800   -18.50300 11.61900 1.000 9.75174  ? 260 VAL A O    1 
ATOM   3776 C  CB   . VAL A 1 237 ? -0.61800  -17.50900 14.45200 1.000 10.69085 ? 260 VAL A CB   1 
ATOM   3777 C  CG1  . VAL A 1 237 ? 0.06300   -16.17900 14.23400 1.000 12.16552 ? 260 VAL A CG1  1 
ATOM   3778 C  CG2  . VAL A 1 237 ? -1.40100  -17.54300 15.76400 1.000 12.09136 ? 260 VAL A CG2  1 
ATOM   3779 H  H    . VAL A 1 237 ? -1.41700  -19.79500 13.41200 1.000 11.01510 ? 260 VAL A H    1 
ATOM   3780 H  HA   . VAL A 1 237 ? -2.30600  -17.22600 13.29400 1.000 10.99350 ? 260 VAL A HA   1 
ATOM   3781 H  HB   . VAL A 1 237 ? 0.08700   -18.17300 14.50400 1.000 12.82707 ? 260 VAL A HB   1 
ATOM   3782 H  HG11 . VAL A 1 237 ? 0.50500   -15.91200 15.05500 1.000 14.59668 ? 260 VAL A HG11 1 
ATOM   3783 H  HG12 . VAL A 1 237 ? 0.71500   -16.27100 13.52200 1.000 14.59668 ? 260 VAL A HG12 1 
ATOM   3784 H  HG13 . VAL A 1 237 ? -0.60400  -15.51900 13.98800 1.000 14.59668 ? 260 VAL A HG13 1 
ATOM   3785 H  HG21 . VAL A 1 237 ? -0.78600  -17.40700 16.50200 1.000 14.50769 ? 260 VAL A HG21 1 
ATOM   3786 H  HG22 . VAL A 1 237 ? -2.06600  -16.83600 15.75400 1.000 14.50769 ? 260 VAL A HG22 1 
ATOM   3787 H  HG23 . VAL A 1 237 ? -1.83700  -18.40500 15.85100 1.000 14.50769 ? 260 VAL A HG23 1 
ATOM   3788 N  N    . THR A 1 238 ? -1.24400  -16.67900 11.18600 1.000 9.52261  ? 261 THR A N    1 
ATOM   3789 C  CA   . THR A 1 238 ? -0.58400  -16.31300 9.93600  1.000 9.61284  ? 261 THR A CA   1 
ATOM   3790 C  C    . THR A 1 238 ? -0.25000  -14.82700 10.01900 1.000 9.89748  ? 261 THR A C    1 
ATOM   3791 O  O    . THR A 1 238 ? -1.15400  -13.98900 10.03400 1.000 10.05060 ? 261 THR A O    1 
ATOM   3792 C  CB   . THR A 1 238 ? -1.46100  -16.60800 8.70900  1.000 10.26922 ? 261 THR A CB   1 
ATOM   3793 O  OG1  . THR A 1 238 ? -2.71000  -15.92700 8.80600  1.000 10.56224 ? 261 THR A OG1  1 
ATOM   3794 C  CG2  . THR A 1 238 ? -1.70900  -18.08700 8.56100  1.000 11.55325 ? 261 THR A CG2  1 
ATOM   3795 H  H    . THR A 1 238 ? -1.90500  -16.16500 11.38200 1.000 11.42518 ? 261 THR A H    1 
ATOM   3796 H  HA   . THR A 1 238 ? 0.23400   -16.82600 9.83900  1.000 11.53345 ? 261 THR A HA   1 
ATOM   3797 H  HB   . THR A 1 238 ? -0.99400  -16.29600 7.91900  1.000 12.32111 ? 261 THR A HB   1 
ATOM   3798 H  HG1  . THR A 1 238 ? -2.58200  -15.11700 8.98800  1.000 12.67274 ? 261 THR A HG1  1 
ATOM   3799 H  HG21 . THR A 1 238 ? -2.28800  -18.25100 7.80000  1.000 13.86195 ? 261 THR A HG21 1 
ATOM   3800 H  HG22 . THR A 1 238 ? -0.86900  -18.55200 8.42400  1.000 13.86195 ? 261 THR A HG22 1 
ATOM   3801 H  HG23 . THR A 1 238 ? -2.13400  -18.43400 9.36000  1.000 13.86195 ? 261 THR A HG23 1 
ATOM   3802 N  N    A TYR A 1 239 ? 1.03800   -14.51300 10.02300 0.799 9.50943  ? 262 TYR A N    1 
ATOM   3803 N  N    B TYR A 1 239 ? 1.03500   -14.50100 10.16500 0.201 9.57955  ? 262 TYR A N    1 
ATOM   3804 C  CA   A TYR A 1 239 ? 1.54700   -13.15200 10.08500 0.799 10.09177 ? 262 TYR A CA   1 
ATOM   3805 C  CA   B TYR A 1 239 ? 1.50900   -13.12600 10.07500 0.201 9.85031  ? 262 TYR A CA   1 
ATOM   3806 C  C    A TYR A 1 239 ? 2.34600   -12.86900 8.82300  0.799 10.15953 ? 262 TYR A C    1 
ATOM   3807 C  C    B TYR A 1 239 ? 2.18400   -12.91400 8.72700  0.201 9.92359  ? 262 TYR A C    1 
ATOM   3808 O  O    A TYR A 1 239 ? 3.09400   -13.72800 8.34600  0.799 9.58900  ? 262 TYR A O    1 
ATOM   3809 O  O    B TYR A 1 239 ? 2.69300   -13.85000 8.10500  0.201 10.07311 ? 262 TYR A O    1 
ATOM   3810 C  CB   A TYR A 1 239 ? 2.43300   -13.05800 11.31900 0.799 10.36016 ? 262 TYR A CB   1 
ATOM   3811 C  CB   B TYR A 1 239 ? 2.51800   -12.78400 11.18100 0.201 10.03818 ? 262 TYR A CB   1 
ATOM   3812 C  CG   A TYR A 1 239 ? 1.72400   -12.86300 12.65000 0.799 8.99948  ? 262 TYR A CG   1 
ATOM   3813 C  CG   B TYR A 1 239 ? 1.98400   -12.80100 12.59900 0.201 12.25637 ? 262 TYR A CG   1 
ATOM   3814 C  CD1  A TYR A 1 239 ? 0.37000   -12.57400 12.73500 0.799 9.48763  ? 262 TYR A CD1  1 
ATOM   3815 C  CD1  B TYR A 1 239 ? 1.20600   -11.76400 13.08900 0.201 12.39968 ? 262 TYR A CD1  1 
ATOM   3816 C  CD2  A TYR A 1 239 ? 2.45000   -12.89400 13.81600 0.799 9.95566  ? 262 TYR A CD2  1 
ATOM   3817 C  CD2  B TYR A 1 239 ? 2.29400   -13.83600 13.45500 0.201 14.12542 ? 262 TYR A CD2  1 
ATOM   3818 C  CE1  A TYR A 1 239 ? -0.23900  -12.30700 13.96100 0.799 10.21827 ? 262 TYR A CE1  1 
ATOM   3819 C  CE1  B TYR A 1 239 ? 0.72900   -11.78100 14.38900 0.201 13.44698 ? 262 TYR A CE1  1 
ATOM   3820 C  CE2  A TYR A 1 239 ? 1.86200   -12.63200 15.04100 0.799 10.99275 ? 262 TYR A CE2  1 
ATOM   3821 C  CE2  B TYR A 1 239 ? 1.84300   -13.85000 14.74700 0.201 14.91175 ? 262 TYR A CE2  1 
ATOM   3822 C  CZ   A TYR A 1 239 ? 0.50800   -12.32200 15.10500 0.799 9.61776  ? 262 TYR A CZ   1 
ATOM   3823 C  CZ   B TYR A 1 239 ? 1.04900   -12.83600 15.20900 0.201 14.22757 ? 262 TYR A CZ   1 
ATOM   3824 O  OH   A TYR A 1 239 ? -0.09100  -12.04000 16.33000 0.799 10.72588 ? 262 TYR A OH   1 
ATOM   3825 O  OH   B TYR A 1 239 ? 0.59800   -12.88900 16.50500 0.201 14.73412 ? 262 TYR A OH   1 
ATOM   3826 H  H    A TYR A 1 239 ? 1.66600   -15.10000 9.98900  0.799 11.40936 ? 262 TYR A H    1 
ATOM   3827 H  H    B TYR A 1 239 ? 1.66000   -15.07100 10.31900 0.201 11.49352 ? 262 TYR A H    1 
ATOM   3828 H  HA   A TYR A 1 239 ? 0.84200   -12.48600 10.12900 0.799 12.10817 ? 262 TYR A HA   1 
ATOM   3829 H  HA   B TYR A 1 239 ? 0.74800   -12.53200 10.17500 0.201 11.81843 ? 262 TYR A HA   1 
ATOM   3830 H  HB2  A TYR A 1 239 ? 2.94200   -13.88100 11.38700 0.799 12.43025 ? 262 TYR A HB2  1 
ATOM   3831 H  HB2  B TYR A 1 239 ? 3.24100   -13.42800 11.14000 0.201 12.04386 ? 262 TYR A HB2  1 
ATOM   3832 H  HB3  A TYR A 1 239 ? 3.03300   -12.30500 11.20300 0.799 12.43025 ? 262 TYR A HB3  1 
ATOM   3833 H  HB3  B TYR A 1 239 ? 2.85800   -11.89100 11.01400 0.201 12.04386 ? 262 TYR A HB3  1 
ATOM   3834 H  HD1  A TYR A 1 239 ? -0.14300  -12.55900 11.95900 0.799 11.38321 ? 262 TYR A HD1  1 
ATOM   3835 H  HD1  B TYR A 1 239 ? 1.00100   -11.04500 12.53600 0.201 14.87767 ? 262 TYR A HD1  1 
ATOM   3836 H  HD2  A TYR A 1 239 ? 3.35700   -13.09600 13.78200 0.799 11.94484 ? 262 TYR A HD2  1 
ATOM   3837 H  HD2  B TYR A 1 239 ? 2.81900   -14.54000 13.14800 0.201 16.94855 ? 262 TYR A HD2  1 
ATOM   3838 H  HE1  A TYR A 1 239 ? -1.14900  -12.11900 14.00000 0.799 12.25998 ? 262 TYR A HE1  1 
ATOM   3839 H  HE1  B TYR A 1 239 ? 0.19800   -11.08600 14.70400 0.201 16.13442 ? 262 TYR A HE1  1 
ATOM   3840 H  HE2  A TYR A 1 239 ? 2.37000   -12.66300 15.81900 0.799 13.18935 ? 262 TYR A HE2  1 
ATOM   3841 H  HE2  B TYR A 1 239 ? 2.07700   -14.55000 15.31200 0.201 17.89215 ? 262 TYR A HE2  1 
ATOM   3842 H  HH   A TYR A 1 239 ? -0.82800  -11.65600 16.20800 0.799 12.86911 ? 262 TYR A HH   1 
ATOM   3843 H  HH   B TYR A 1 239 ? 0.65000   -13.67500 16.79600 0.201 17.67900 ? 262 TYR A HH   1 
ATOM   3844 N  N    . PHE A 1 240 ? 2.20500   -11.66100 8.29100  1.000 10.11332 ? 263 PHE A N    1 
ATOM   3845 C  CA   . PHE A 1 240 ? 2.86100   -11.33900 7.03400  1.000 10.33482 ? 263 PHE A CA   1 
ATOM   3846 C  C    . PHE A 1 240 ? 3.20200   -9.85600  7.01600  1.000 10.69289 ? 263 PHE A C    1 
ATOM   3847 O  O    . PHE A 1 240 ? 2.38400   -9.01800  7.39400  1.000 10.47724 ? 263 PHE A O    1 
ATOM   3848 C  CB   . PHE A 1 240 ? 1.96300   -11.69100 5.84900  1.000 10.39166 ? 263 PHE A CB   1 
ATOM   3849 C  CG   . PHE A 1 240 ? 2.58400   -11.39700 4.52600  1.000 10.87713 ? 263 PHE A CG   1 
ATOM   3850 C  CD1  . PHE A 1 240 ? 3.68200   -12.11600 4.10200  1.000 11.28409 ? 263 PHE A CD1  1 
ATOM   3851 C  CD2  . PHE A 1 240 ? 2.08300   -10.39900 3.70900  1.000 11.58349 ? 263 PHE A CD2  1 
ATOM   3852 C  CE1  . PHE A 1 240 ? 4.27300   -11.86100 2.87600  1.000 12.29666 ? 263 PHE A CE1  1 
ATOM   3853 C  CE2  . PHE A 1 240 ? 2.67000   -10.13600 2.47300  1.000 11.84078 ? 263 PHE A CE2  1 
ATOM   3854 C  CZ   . PHE A 1 240 ? 3.77400   -10.86200 2.07000  1.000 12.65093 ? 263 PHE A CZ   1 
ATOM   3855 H  H    A PHE A 1 240 ? 1.74200   -11.02200 8.63300  0.799 12.13403 ? 263 PHE A H    1 
ATOM   3856 H  H    B PHE A 1 240 ? 1.85200   -10.99100 8.69800  0.201 12.13403 ? 263 PHE A H    1 
ATOM   3857 H  HA   . PHE A 1 240 ? 3.69000   -11.83900 6.95900  1.000 12.39984 ? 263 PHE A HA   1 
ATOM   3858 H  HB2  . PHE A 1 240 ? 1.76300   -12.64000 5.87900  1.000 12.46804 ? 263 PHE A HB2  1 
ATOM   3859 H  HB3  . PHE A 1 240 ? 1.14400   -11.17700 5.91400  1.000 12.46804 ? 263 PHE A HB3  1 
ATOM   3860 H  HD1  . PHE A 1 240 ? 4.03200   -12.78200 4.64900  1.000 13.53895 ? 263 PHE A HD1  1 
ATOM   3861 H  HD2  . PHE A 1 240 ? 1.34900   -9.90100  3.98700  1.000 13.89823 ? 263 PHE A HD2  1 
ATOM   3862 H  HE1  . PHE A 1 240 ? 5.00400   -12.36300 2.59700  1.000 14.75404 ? 263 PHE A HE1  1 
ATOM   3863 H  HE2  . PHE A 1 240 ? 2.32000   -9.47400  1.92200  1.000 14.20698 ? 263 PHE A HE2  1 
ATOM   3864 H  HZ   . PHE A 1 240 ? 4.18000   -10.67600 1.25500  1.000 15.17917 ? 263 PHE A HZ   1 
ATOM   3865 N  N    . THR A 1 241 ? 4.40500   -9.53100  6.55300  1.000 10.28414 ? 264 THR A N    1 
ATOM   3866 C  CA   . THR A 1 241 ? 4.82300   -8.13900  6.47100  1.000 10.96954 ? 264 THR A CA   1 
ATOM   3867 C  C    . THR A 1 241 ? 5.75500   -7.97500  5.28100  1.000 11.21886 ? 264 THR A C    1 
ATOM   3868 O  O    . THR A 1 241 ? 6.36300   -8.93900  4.81100  1.000 12.38958 ? 264 THR A O    1 
ATOM   3869 C  CB   . THR A 1 241 ? 5.43300   -7.67500  7.80600  1.000 11.46818 ? 264 THR A CB   1 
ATOM   3870 O  OG1  . THR A 1 241 ? 5.53000   -6.24000  7.80600  1.000 11.90431 ? 264 THR A OG1  1 
ATOM   3871 C  CG2  . THR A 1 241 ? 6.79100   -8.29700  8.06900  1.000 12.23329 ? 264 THR A CG2  1 
ATOM   3872 H  H    . THR A 1 241 ? 4.99400   -10.09700 6.28200  1.000 12.33902 ? 264 THR A H    1 
ATOM   3873 H  HA   . THR A 1 241 ? 4.06900   -7.55600  6.29500  1.000 13.16150 ? 264 THR A HA   1 
ATOM   3874 H  HB   . THR A 1 241 ? 4.85900   -7.96400  8.53200  1.000 13.75986 ? 264 THR A HB   1 
ATOM   3875 H  HG1  . THR A 1 241 ? 4.76200   -5.90100  7.82300  1.000 14.28322 ? 264 THR A HG1  1 
ATOM   3876 H  HG21 . THR A 1 241 ? 7.09600   -8.06300  8.96000  1.000 14.67799 ? 264 THR A HG21 1 
ATOM   3877 H  HG22 . THR A 1 241 ? 6.73200   -9.26300  8.00000  1.000 14.67799 ? 264 THR A HG22 1 
ATOM   3878 H  HG23 . THR A 1 241 ? 7.43500   -7.97400  7.42000  1.000 14.67799 ? 264 THR A HG23 1 
ATOM   3879 N  N    . GLN A 1 242 ? 5.85600   -6.74400  4.80300  1.000 11.18354 ? 265 GLN A N    1 
ATOM   3880 C  CA   . GLN A 1 242 ? 6.45400   -6.47000  3.50800  1.000 12.08443 ? 265 GLN A CA   1 
ATOM   3881 C  C    . GLN A 1 242 ? 7.53900   -5.41400  3.59300  1.000 12.56096 ? 265 GLN A C    1 
ATOM   3882 O  O    . GLN A 1 242 ? 7.64600   -4.69300  4.58800  1.000 12.96716 ? 265 GLN A O    1 
ATOM   3883 C  CB   . GLN A 1 242 ? 5.36300   -6.04400  2.51400  1.000 12.17854 ? 265 GLN A CB   1 
ATOM   3884 C  CG   . GLN A 1 242 ? 4.34100   -7.14300  2.31100  1.000 13.09365 ? 265 GLN A CG   1 
ATOM   3885 C  CD   . GLN A 1 242 ? 3.26100   -6.75500  1.35000  1.000 12.61356 ? 265 GLN A CD   1 
ATOM   3886 O  OE1  . GLN A 1 242 ? 3.50300   -6.67700  0.14700  1.000 14.04274 ? 265 GLN A OE1  1 
ATOM   3887 N  NE2  . GLN A 1 242 ? 2.06800   -6.47000  1.86200  1.000 12.32982 ? 265 GLN A NE2  1 
ATOM   3888 H  H    . GLN A 1 242 ? 5.58000   -6.04300  5.21700  1.000 13.41830 ? 265 GLN A H    1 
ATOM   3889 H  HA   . GLN A 1 242 ? 6.89600   -7.27000  3.18600  1.000 14.49937 ? 265 GLN A HA   1 
ATOM   3890 H  HB2  . GLN A 1 242 ? 4.90500   -5.26100  2.85700  1.000 14.61229 ? 265 GLN A HB2  1 
ATOM   3891 H  HB3  . GLN A 1 242 ? 5.77000   -5.84300  1.65800  1.000 14.61229 ? 265 GLN A HB3  1 
ATOM   3892 H  HG2  . GLN A 1 242 ? 4.78800   -7.92900  1.95900  1.000 15.71043 ? 265 GLN A HG2  1 
ATOM   3893 H  HG3  . GLN A 1 242 ? 3.92600   -7.35100  3.16200  1.000 15.71043 ? 265 GLN A HG3  1 
ATOM   3894 H  HE21 . GLN A 1 242 ? 1.94300   -6.51400  2.71200  1.000 14.79383 ? 265 GLN A HE21 1 
ATOM   3895 H  HE22 . GLN A 1 242 ? 1.42000   -6.24300  1.34400  1.000 14.79383 ? 265 GLN A HE22 1 
ATOM   3896 N  N    . PRO A 1 243 ? 8.37900   -5.30800  2.55300  1.000 13.47372 ? 266 PRO A N    1 
ATOM   3897 C  CA   . PRO A 1 243 ? 9.53500   -4.40300  2.63800  1.000 15.34624 ? 266 PRO A CA   1 
ATOM   3898 C  C    . PRO A 1 243 ? 9.21300   -2.92300  2.47800  1.000 13.92736 ? 266 PRO A C    1 
ATOM   3899 O  O    . PRO A 1 243 ? 10.00500  -2.09100  2.94000  1.000 15.78333 ? 266 PRO A O    1 
ATOM   3900 C  CB   . PRO A 1 243 ? 10.45300  -4.87500  1.50200  1.000 17.12397 ? 266 PRO A CB   1 
ATOM   3901 C  CG   . PRO A 1 243 ? 9.83900   -6.07900  0.91600  1.000 18.41105 ? 266 PRO A CG   1 
ATOM   3902 C  CD   . PRO A 1 243 ? 8.45900   -6.24800  1.41800  1.000 15.33556 ? 266 PRO A CD   1 
ATOM   3903 H  HA   . PRO A 1 243 ? 9.97400   -4.53800  3.49300  1.000 18.41354 ? 266 PRO A HA   1 
ATOM   3904 H  HB2  . PRO A 1 243 ? 10.52600  -4.17400  0.83600  1.000 20.54681 ? 266 PRO A HB2  1 
ATOM   3905 H  HB3  . PRO A 1 243 ? 11.32900  -5.08300  1.86200  1.000 20.54681 ? 266 PRO A HB3  1 
ATOM   3906 H  HG2  . PRO A 1 243 ? 9.82600   -5.98100  -0.04900 1.000 22.09131 ? 266 PRO A HG2  1 
ATOM   3907 H  HG3  . PRO A 1 243 ? 10.37300  -6.85000  1.16400  1.000 22.09131 ? 266 PRO A HG3  1 
ATOM   3908 H  HD2  . PRO A 1 243 ? 7.81400   -6.01400  0.73300  1.000 18.40072 ? 266 PRO A HD2  1 
ATOM   3909 H  HD3  . PRO A 1 243 ? 8.31100   -7.15900  1.71600  1.000 18.40072 ? 266 PRO A HD3  1 
ATOM   3910 N  N    . GLN A 1 244 ? 8.11500   -2.57200  1.82200  1.000 13.50099 ? 267 GLN A N    1 
ATOM   3911 C  CA   . GLN A 1 244 ? 7.85200   -1.18700  1.44500  1.000 13.87336 ? 267 GLN A CA   1 
ATOM   3912 C  C    . GLN A 1 244 ? 6.91800   -0.53500  2.44300  1.000 13.28567 ? 267 GLN A C    1 
ATOM   3913 O  O    . GLN A 1 244 ? 5.88400   -1.12400  2.79600  1.000 12.63012 ? 267 GLN A O    1 
ATOM   3914 C  CB   . GLN A 1 244 ? 7.20200   -1.12200  0.07100  1.000 14.22469 ? 267 GLN A CB   1 
ATOM   3915 C  CG   . GLN A 1 244 ? 7.98000   -1.81500  -1.03700 1.000 14.86079 ? 267 GLN A CG   1 
ATOM   3916 C  CD   . GLN A 1 244 ? 7.58000   -3.26400  -1.20700 1.000 14.51997 ? 267 GLN A CD   1 
ATOM   3917 O  OE1  . GLN A 1 244 ? 6.80300   -3.81900  -0.42800 1.000 14.72434 ? 267 GLN A OE1  1 
ATOM   3918 N  NE2  . GLN A 1 244 ? 8.09800   -3.88700  -2.24300 1.000 15.71680 ? 267 GLN A NE2  1 
ATOM   3919 H  H    . GLN A 1 244 ? 7.50000   -3.12100  1.58100  1.000 16.19924 ? 267 GLN A H    1 
ATOM   3920 H  HA   . GLN A 1 244 ? 8.69300   -0.70400  1.42800  1.000 16.64609 ? 267 GLN A HA   1 
ATOM   3921 H  HB2  . GLN A 1 244 ? 6.33000   -1.54400  0.12300  1.000 17.06768 ? 267 GLN A HB2  1 
ATOM   3922 H  HB3  . GLN A 1 244 ? 7.10400   -0.19000  -0.18000 1.000 17.06768 ? 267 GLN A HB3  1 
ATOM   3923 H  HG2  . GLN A 1 244 ? 7.81400   -1.35700  -1.87500 1.000 17.83099 ? 267 GLN A HG2  1 
ATOM   3924 H  HG3  . GLN A 1 244 ? 8.92600   -1.78700  -0.82500 1.000 17.83099 ? 267 GLN A HG3  1 
ATOM   3925 H  HE21 . GLN A 1 244 ? 8.62900   -3.47000  -2.77500 1.000 18.85821 ? 267 GLN A HE21 1 
ATOM   3926 H  HE22 . GLN A 1 244 ? 7.90500   -4.71300  -2.38900 1.000 18.85821 ? 267 GLN A HE22 1 
ATOM   3927 N  N    . PRO A 1 245 ? 7.21500   0.68000   2.90400  1.000 14.30165 ? 268 PRO A N    1 
ATOM   3928 C  CA   . PRO A 1 245 ? 6.33900   1.29300   3.91600  1.000 15.52490 ? 268 PRO A CA   1 
ATOM   3929 C  C    . PRO A 1 245 ? 4.87900   1.37700   3.50700  1.000 15.11637 ? 268 PRO A C    1 
ATOM   3930 O  O    . PRO A 1 245 ? 3.99900   1.20800   4.36200  1.000 15.11472 ? 268 PRO A O    1 
ATOM   3931 C  CB   . PRO A 1 245 ? 6.95200   2.68000   4.13400  1.000 17.57020 ? 268 PRO A CB   1 
ATOM   3932 C  CG   . PRO A 1 245 ? 8.35100   2.59100   3.61600  1.000 19.17133 ? 268 PRO A CG   1 
ATOM   3933 C  CD   . PRO A 1 245 ? 8.40000   1.50400   2.60800  1.000 16.29516 ? 268 PRO A CD   1 
ATOM   3934 H  HA   . PRO A 1 245 ? 6.40500   0.78100   4.73700  1.000 18.62794 ? 268 PRO A HA   1 
ATOM   3935 H  HB2  . PRO A 1 245 ? 6.44400   3.34300   3.64100  1.000 21.08228 ? 268 PRO A HB2  1 
ATOM   3936 H  HB3  . PRO A 1 245 ? 6.94800   2.89500   5.08000  1.000 21.08228 ? 268 PRO A HB3  1 
ATOM   3937 H  HG2  . PRO A 1 245 ? 8.59400   3.43800   3.20900  1.000 23.00364 ? 268 PRO A HG2  1 
ATOM   3938 H  HG3  . PRO A 1 245 ? 8.95000   2.39300   4.35200  1.000 23.00364 ? 268 PRO A HG3  1 
ATOM   3939 H  HD2  . PRO A 1 245 ? 8.34700   1.86800   1.71000  1.000 19.55224 ? 268 PRO A HD2  1 
ATOM   3940 H  HD3  . PRO A 1 245 ? 9.21200   0.98300   2.70700  1.000 19.55224 ? 268 PRO A HD3  1 
ATOM   3941 N  N    . LYS A 1 246 ? 4.59100   1.65700   2.23400  1.000 14.28960 ? 269 LYS A N    1 
ATOM   3942 C  CA   . LYS A 1 246 ? 3.23000   1.82700   1.75800  1.000 14.74981 ? 269 LYS A CA   1 
ATOM   3943 C  C    . LYS A 1 246 ? 2.71800   0.60500   1.00200  1.000 13.74273 ? 269 LYS A C    1 
ATOM   3944 O  O    . LYS A 1 246 ? 1.78000   0.72400   0.21500  1.000 15.23744 ? 269 LYS A O    1 
ATOM   3945 C  CB   . LYS A 1 246 ? 3.12600   3.07700   0.88600  1.000 16.41291 ? 269 LYS A CB   1 
ATOM   3946 C  CG   . LYS A 1 246 ? 3.46000   4.37200   1.58400  1.000 20.06350 ? 269 LYS A CG   1 
ATOM   3947 C  CD   . LYS A 1 246 ? 3.22300   5.54800   0.62700  1.000 24.26681 ? 269 LYS A CD   1 
ATOM   3948 C  CE   . LYS A 1 246 ? 3.74100   6.86400   1.15700  1.000 29.09697 ? 269 LYS A CE   1 
ATOM   3949 N  NZ   . LYS A 1 246 ? 3.65700   7.90900   0.09500  1.000 31.50634 ? 269 LYS A NZ   1 
ATOM   3950 H  H    . LYS A 1 246 ? 5.18400   1.75500   1.61900  1.000 17.14557 ? 269 LYS A H    1 
ATOM   3951 H  HA   . LYS A 1 246 ? 2.65400   1.95400   2.52800  1.000 17.69782 ? 269 LYS A HA   1 
ATOM   3952 H  HB2  . LYS A 1 246 ? 3.73900   2.98300   0.14000  1.000 19.69355 ? 269 LYS A HB2  1 
ATOM   3953 H  HB3  . LYS A 1 246 ? 2.21500   3.14900   0.56000  1.000 19.69355 ? 269 LYS A HB3  1 
ATOM   3954 H  HG2  . LYS A 1 246 ? 2.89100   4.48300   2.36200  1.000 24.07425 ? 269 LYS A HG2  1 
ATOM   3955 H  HG3  . LYS A 1 246 ? 4.39200   4.37000   1.85200  1.000 24.07425 ? 269 LYS A HG3  1 
ATOM   3956 H  HD2  . LYS A 1 246 ? 3.67500   5.36700   -0.21100 1.000 29.11823 ? 269 LYS A HD2  1 
ATOM   3957 H  HD3  . LYS A 1 246 ? 2.27000   5.64300   0.47600  1.000 29.11823 ? 269 LYS A HD3  1 
ATOM   3958 H  HE2  . LYS A 1 246 ? 3.20400   7.14600   1.91400  1.000 34.91441 ? 269 LYS A HE2  1 
ATOM   3959 H  HE3  . LYS A 1 246 ? 4.66800   6.76600   1.42500  1.000 34.91441 ? 269 LYS A HE3  1 
ATOM   3960 H  HZ1  . LYS A 1 246 ? 3.94500   8.68900   0.41200  1.000 37.80565 ? 269 LYS A HZ1  1 
ATOM   3961 H  HZ2  . LYS A 1 246 ? 4.15900   7.67600   -0.60100 1.000 37.80565 ? 269 LYS A HZ2  1 
ATOM   3962 H  HZ3  . LYS A 1 246 ? 2.81400   8.00100   -0.17500 1.000 37.80565 ? 269 LYS A HZ3  1 
ATOM   3963 N  N    . ALA A 1 247 ? 3.30400   -0.56700  1.23100  1.000 12.67947 ? 270 ALA A N    1 
ATOM   3964 C  CA   . ALA A 1 247 ? 2.78900   -1.77200  0.60300  1.000 13.07435 ? 270 ALA A CA   1 
ATOM   3965 C  C    . ALA A 1 247 ? 1.30700   -1.96800  0.92800  1.000 13.57830 ? 270 ALA A C    1 
ATOM   3966 O  O    . ALA A 1 247 ? 0.82000   -1.63800  2.02000  1.000 14.20997 ? 270 ALA A O    1 
ATOM   3967 C  CB   . ALA A 1 247 ? 3.58700   -2.99500  1.06100  1.000 13.09863 ? 270 ALA A CB   1 
ATOM   3968 H  H    . ALA A 1 247 ? 3.98900   -0.68600  1.73600  1.000 15.21341 ? 270 ALA A H    1 
ATOM   3969 H  HA   . ALA A 1 247 ? 2.87900   -1.69100  -0.35900 1.000 15.68727 ? 270 ALA A HA   1 
ATOM   3970 H  HB1  . ALA A 1 247 ? 3.19700   -3.79200  0.66900  1.000 15.71641 ? 270 ALA A HB1  1 
ATOM   3971 H  HB2  . ALA A 1 247 ? 4.50700   -2.89900  0.76900  1.000 15.71641 ? 270 ALA A HB2  1 
ATOM   3972 H  HB3  . ALA A 1 247 ? 3.55100   -3.05100  2.02900  1.000 15.71641 ? 270 ALA A HB3  1 
ATOM   3973 N  N    . GLU A 1 248 ? 0.58700   -2.53300  -0.03300 1.000 14.87569 ? 271 GLU A N    1 
ATOM   3974 C  CA   . GLU A 1 248 ? -0.82400  -2.82500  0.15400  1.000 16.84276 ? 271 GLU A CA   1 
ATOM   3975 C  C    . GLU A 1 248 ? -1.01800  -4.14700  0.88300  1.000 14.16256 ? 271 GLU A C    1 
ATOM   3976 O  O    . GLU A 1 248 ? -0.12500  -4.98500  0.94300  1.000 14.26721 ? 271 GLU A O    1 
ATOM   3977 C  CB   . GLU A 1 248 ? -1.55000  -2.84300  -1.18700 1.000 22.40290 ? 271 GLU A CB   1 
ATOM   3978 C  CG   . GLU A 1 248 ? -1.49800  -1.49000  -1.87700 1.000 30.11578 ? 271 GLU A CG   1 
ATOM   3979 C  CD   . GLU A 1 248 ? -2.39500  -1.41800  -3.08100 1.000 36.28347 ? 271 GLU A CD   1 
ATOM   3980 O  OE1  . GLU A 1 248 ? -3.61900  -1.61200  -2.92700 1.000 39.30789 ? 271 GLU A OE1  1 
ATOM   3981 O  OE2  . GLU A 1 248 ? -1.87000  -1.17700  -4.17800 1.000 38.70934 ? 271 GLU A OE2  1 
ATOM   3982 H  H    . GLU A 1 248 ? 0.89400   -2.75800  -0.80400 1.000 17.84888 ? 271 GLU A H    1 
ATOM   3983 H  HA   . GLU A 1 248 ? -1.22400  -2.13100  0.70100  1.000 20.20937 ? 271 GLU A HA   1 
ATOM   3984 H  HB2  . GLU A 1 248 ? -1.13000  -3.49600  -1.76800 1.000 26.88153 ? 271 GLU A HB2  1 
ATOM   3985 H  HB3  . GLU A 1 248 ? -2.48100  -3.07600  -1.04400 1.000 26.88153 ? 271 GLU A HB3  1 
ATOM   3986 H  HG2  . GLU A 1 248 ? -1.78100  -0.80500  -1.25100 1.000 36.13698 ? 271 GLU A HG2  1 
ATOM   3987 H  HG3  . GLU A 1 248 ? -0.58900  -1.31900  -2.16900 1.000 36.13698 ? 271 GLU A HG3  1 
ATOM   3988 N  N    A SER A 1 249 ? -2.20200  -4.31400  1.46100  0.538 14.67439 ? 272 SER A N    1 
ATOM   3989 N  N    B SER A 1 249 ? -2.22300  -4.31300  1.42000  0.462 14.65750 ? 272 SER A N    1 
ATOM   3990 C  CA   A SER A 1 249 ? -2.49700  -5.53300  2.19700  0.538 15.15021 ? 272 SER A CA   1 
ATOM   3991 C  CA   B SER A 1 249 ? -2.60100  -5.52600  2.12600  0.462 14.88299 ? 272 SER A CA   1 
ATOM   3992 C  C    A SER A 1 249 ? -2.51700  -6.74000  1.27000  0.538 14.19102 ? 272 SER A C    1 
ATOM   3993 C  C    B SER A 1 249 ? -2.47300  -6.74700  1.22500  0.462 14.42613 ? 272 SER A C    1 
ATOM   3994 O  O    A SER A 1 249 ? -2.85100  -6.64400  0.08700  0.538 14.38924 ? 272 SER A O    1 
ATOM   3995 O  O    B SER A 1 249 ? -2.64400  -6.66800  0.00500  0.462 15.40299 ? 272 SER A O    1 
ATOM   3996 C  CB   A SER A 1 249 ? -3.84900  -5.42900  2.89700  0.538 17.04762 ? 272 SER A CB   1 
ATOM   3997 C  CB   B SER A 1 249 ? -4.05700  -5.40600  2.57800  0.462 16.29414 ? 272 SER A CB   1 
ATOM   3998 O  OG   A SER A 1 249 ? -3.80300  -4.49100  3.94700  0.538 17.52407 ? 272 SER A OG   1 
ATOM   3999 O  OG   B SER A 1 249 ? -4.92600  -5.23200  1.46700  0.462 16.08207 ? 272 SER A OG   1 
ATOM   4000 H  H    A SER A 1 249 ? -2.84400  -3.74200  1.44100  0.538 17.60732 ? 272 SER A H    1 
ATOM   4001 H  H    B SER A 1 249 ? -2.85000  -3.72500  1.38700  0.462 17.58705 ? 272 SER A H    1 
ATOM   4002 H  HA   A SER A 1 249 ? -1.80700  -5.66300  2.86700  0.538 18.17830 ? 272 SER A HA   1 
ATOM   4003 H  HA   B SER A 1 249 ? -2.02100  -5.64800  2.89400  0.462 17.85764 ? 272 SER A HA   1 
ATOM   4004 H  HB2  A SER A 1 249 ? -4.51700  -5.14800  2.25200  0.538 20.45520 ? 272 SER A HB2  1 
ATOM   4005 H  HB2  B SER A 1 249 ? -4.30800  -6.21600  3.04900  0.462 19.55102 ? 272 SER A HB2  1 
ATOM   4006 H  HB3  A SER A 1 249 ? -4.08400  -6.29800  3.26100  0.538 20.45520 ? 272 SER A HB3  1 
ATOM   4007 H  HB3  B SER A 1 249 ? -4.14100  -4.64000  3.16600  0.462 19.55102 ? 272 SER A HB3  1 
ATOM   4008 H  HG   A SER A 1 249 ? -3.60700  -3.73200  3.64500  0.538 21.02694 ? 272 SER A HG   1 
ATOM   4009 H  HG   B SER A 1 249 ? -4.98000  -5.94700  1.03000  0.462 19.29653 ? 272 SER A HG   1 
ATOM   4010 N  N    . ARG A 1 250 ? -2.18100  -7.89800  1.83900  1.000 13.07579 ? 273 ARG A N    1 
ATOM   4011 C  CA   . ARG A 1 250 ? -2.10400  -9.16400  1.11300  1.000 12.50707 ? 273 ARG A CA   1 
ATOM   4012 C  C    . ARG A 1 250 ? -2.83700  -10.26300 1.88800  1.000 11.77932 ? 273 ARG A C    1 
ATOM   4013 O  O    . ARG A 1 250 ? -2.25500  -11.25300 2.32900  1.000 12.67081 ? 273 ARG A O    1 
ATOM   4014 C  CB   . ARG A 1 250 ? -0.64800  -9.53200  0.82700  1.000 13.09433 ? 273 ARG A CB   1 
ATOM   4015 C  CG   . ARG A 1 250 ? 0.03900   -8.62300  -0.18700 1.000 13.34659 ? 273 ARG A CG   1 
ATOM   4016 C  CD   . ARG A 1 250 ? -0.56200  -8.73400  -1.59100 1.000 15.37833 ? 273 ARG A CD   1 
ATOM   4017 N  NE   . ARG A 1 250 ? -0.56900  -10.10100 -2.09500 1.000 15.30858 ? 273 ARG A NE   1 
ATOM   4018 C  CZ   . ARG A 1 250 ? 0.44200   -10.68600 -2.73100 1.000 16.07649 ? 273 ARG A CZ   1 
ATOM   4019 N  NH1  . ARG A 1 250 ? 1.59000   -10.06200 -2.92400 1.000 18.07582 ? 273 ARG A NH1  1 
ATOM   4020 N  NH2  . ARG A 1 250 ? 0.29600   -11.93300 -3.17900 1.000 18.40577 ? 273 ARG A NH2  1 
ATOM   4021 H  H    . ARG A 1 250 ? -1.98700  -7.97900  2.67300  1.000 15.68900 ? 273 ARG A H    1 
ATOM   4022 H  HA   . ARG A 1 250 ? -2.56600  -9.06500  0.26600  1.000 15.00653 ? 273 ARG A HA   1 
ATOM   4023 H  HB2  . ARG A 1 250 ? -0.14700  -9.47900  1.65600  1.000 15.71125 ? 273 ARG A HB2  1 
ATOM   4024 H  HB3  . ARG A 1 250 ? -0.61900  -10.43600 0.47800  1.000 15.71125 ? 273 ARG A HB3  1 
ATOM   4025 H  HG2  . ARG A 1 250 ? -0.04900  -7.70100  0.10300  1.000 16.01395 ? 273 ARG A HG2  1 
ATOM   4026 H  HG3  . ARG A 1 250 ? 0.97700   -8.86400  -0.24400 1.000 16.01395 ? 273 ARG A HG3  1 
ATOM   4027 H  HD2  . ARG A 1 250 ? -1.47900  -8.41800  -1.56900 1.000 18.45205 ? 273 ARG A HD2  1 
ATOM   4028 H  HD3  . ARG A 1 250 ? -0.03900  -8.19200  -2.20300 1.000 18.45205 ? 273 ARG A HD3  1 
ATOM   4029 H  HE   . ARG A 1 250 ? -1.28300  -10.56500 -1.97200 1.000 18.36835 ? 273 ARG A HE   1 
ATOM   4030 H  HH11 . ARG A 1 250 ? 1.69600   -9.25800  -2.63600 1.000 21.68904 ? 273 ARG A HH11 1 
ATOM   4031 H  HH12 . ARG A 1 250 ? 2.23100   -10.45800 -3.33800 1.000 21.68904 ? 273 ARG A HH12 1 
ATOM   4032 H  HH21 . ARG A 1 250 ? -0.44600  -12.35100 -3.05500 1.000 22.08498 ? 273 ARG A HH21 1 
ATOM   4033 H  HH22 . ARG A 1 250 ? 0.94400   -12.32100 -3.59100 1.000 22.08498 ? 273 ARG A HH22 1 
ATOM   4034 N  N    A ARG A 1 251 ? -4.15000  -10.08600 2.04000  0.388 12.44607 ? 274 ARG A N    1 
ATOM   4035 N  N    B ARG A 1 251 ? -4.15000  -10.08900 2.04900  0.612 11.63264 ? 274 ARG A N    1 
ATOM   4036 C  CA   A ARG A 1 251 ? -4.95000  -11.09700 2.72300  0.388 13.02821 ? 274 ARG A CA   1 
ATOM   4037 C  CA   B ARG A 1 251 ? -4.94200  -11.10600 2.73100  0.612 11.54541 ? 274 ARG A CA   1 
ATOM   4038 C  C    A ARG A 1 251 ? -4.91000  -12.42800 1.98300  0.388 12.79893 ? 274 ARG A C    1 
ATOM   4039 C  C    B ARG A 1 251 ? -4.90000  -12.43300 1.98500  0.612 11.85336 ? 274 ARG A C    1 
ATOM   4040 O  O    A ARG A 1 251 ? -5.02600  -13.49000 2.60700  0.388 13.12103 ? 274 ARG A O    1 
ATOM   4041 O  O    B ARG A 1 251 ? -5.00100  -13.49800 2.60800  0.612 12.18908 ? 274 ARG A O    1 
ATOM   4042 C  CB   A ARG A 1 251 ? -6.38100  -10.59800 2.90500  0.388 14.09412 ? 274 ARG A CB   1 
ATOM   4043 C  CB   B ARG A 1 251 ? -6.37500  -10.62400 2.94000  0.612 11.64227 ? 274 ARG A CB   1 
ATOM   4044 C  CG   A ARG A 1 251 ? -6.44300  -9.36200  3.78400  0.388 15.31203 ? 274 ARG A CG   1 
ATOM   4045 C  CG   B ARG A 1 251 ? -6.45800  -9.46200  3.91400  0.612 12.53624 ? 274 ARG A CG   1 
ATOM   4046 C  CD   A ARG A 1 251 ? -7.78700  -8.66600  3.76800  0.388 16.83785 ? 274 ARG A CD   1 
ATOM   4047 C  CD   B ARG A 1 251 ? -7.86600  -8.95000  4.10300  0.612 14.01715 ? 274 ARG A CD   1 
ATOM   4048 N  NE   A ARG A 1 251 ? -7.73500  -7.44900  4.57200  0.388 18.60710 ? 274 ARG A NE   1 
ATOM   4049 N  NE   B ARG A 1 251 ? -8.33600  -8.23100  2.92600  0.612 15.63373 ? 274 ARG A NE   1 
ATOM   4050 C  CZ   A ARG A 1 251 ? -7.40200  -6.25100  4.10800  0.388 19.12719 ? 274 ARG A CZ   1 
ATOM   4051 C  CZ   B ARG A 1 251 ? -8.11800  -6.94500  2.69300  0.612 17.89404 ? 274 ARG A CZ   1 
ATOM   4052 N  NH1  A ARG A 1 251 ? -7.14600  -6.04800  2.82400  0.388 19.20694 ? 274 ARG A NH1  1 
ATOM   4053 N  NH1  B ARG A 1 251 ? -7.42900  -6.19500  3.53900  0.612 18.61696 ? 274 ARG A NH1  1 
ATOM   4054 N  NH2  A ARG A 1 251 ? -7.32800  -5.22900  4.95400  0.388 19.58618 ? 274 ARG A NH2  1 
ATOM   4055 N  NH2  B ARG A 1 251 ? -8.59100  -6.40100  1.57800  0.612 18.46032 ? 274 ARG A NH2  1 
ATOM   4056 H  H    A ARG A 1 251 ? -4.59300  -9.40300  1.76200  0.388 14.93333 ? 274 ARG A H    1 
ATOM   4057 H  H    B ARG A 1 251 ? -4.59600  -9.40500  1.77700  0.612 13.95722 ? 274 ARG A H    1 
ATOM   4058 H  HA   A ARG A 1 251 ? -4.58700  -11.25000 3.61000  0.388 15.63191 ? 274 ARG A HA   1 
ATOM   4059 H  HA   B ARG A 1 251 ? -4.57000  -11.25600 3.61400  0.612 13.85255 ? 274 ARG A HA   1 
ATOM   4060 H  HB2  A ARG A 1 251 ? -6.75300  -10.37200 2.03700  0.388 16.91099 ? 274 ARG A HB2  1 
ATOM   4061 H  HB2  B ARG A 1 251 ? -6.73900  -10.33200 2.09000  0.612 13.96877 ? 274 ARG A HB2  1 
ATOM   4062 H  HB3  A ARG A 1 251 ? -6.91200  -11.29400 3.32200  0.388 16.91099 ? 274 ARG A HB3  1 
ATOM   4063 H  HB3  B ARG A 1 251 ? -6.90700  -11.35400 3.29500  0.612 13.96877 ? 274 ARG A HB3  1 
ATOM   4064 H  HG2  A ARG A 1 251 ? -6.25600  -9.62100  4.70000  0.388 18.37248 ? 274 ARG A HG2  1 
ATOM   4065 H  HG2  B ARG A 1 251 ? -6.12700  -9.75100  4.77900  0.612 15.04154 ? 274 ARG A HG2  1 
ATOM   4066 H  HG3  A ARG A 1 251 ? -5.77800  -8.72700  3.47600  0.388 18.37248 ? 274 ARG A HG3  1 
ATOM   4067 H  HG3  B ARG A 1 251 ? -5.91600  -8.73000  3.58000  0.612 15.04154 ? 274 ARG A HG3  1 
ATOM   4068 H  HD2  A ARG A 1 251 ? -8.02000  -8.42700  2.85800  0.388 20.20347 ? 274 ARG A HD2  1 
ATOM   4069 H  HD2  B ARG A 1 251 ? -8.46200  -9.69900  4.26100  0.612 16.81863 ? 274 ARG A HD2  1 
ATOM   4070 H  HD3  A ARG A 1 251 ? -8.46300  -9.25500  4.14000  0.388 20.20347 ? 274 ARG A HD3  1 
ATOM   4071 H  HD3  B ARG A 1 251 ? -7.88900  -8.34300  4.85900  0.612 16.81863 ? 274 ARG A HD3  1 
ATOM   4072 H  HE   A ARG A 1 251 ? -7.93500  -7.51300  5.40600  0.388 22.32657 ? 274 ARG A HE   1 
ATOM   4073 H  HE   B ARG A 1 251 ? -8.78700  -8.67300  2.34100  0.612 18.75853 ? 274 ARG A HE   1 
ATOM   4074 H  HH11 A ARG A 1 251 ? -7.19300  -6.70200  2.26700  0.388 23.04638 ? 274 ARG A HH11 1 
ATOM   4075 H  HH11 B ARG A 1 251 ? -7.11000  -6.54000  4.25900  0.612 22.33840 ? 274 ARG A HH11 1 
ATOM   4076 H  HH12 A ARG A 1 251 ? -6.93200  -5.26200  2.54700  0.388 23.04638 ? 274 ARG A HH12 1 
ATOM   4077 H  HH12 B ARG A 1 251 ? -7.29900  -5.36200  3.36700  0.612 22.33840 ? 274 ARG A HH12 1 
ATOM   4078 H  HH21 A ARG A 1 251 ? -7.49400  -5.34900  5.78900  0.388 23.50147 ? 274 ARG A HH21 1 
ATOM   4079 H  HH21 B ARG A 1 251 ? -9.03200  -6.88300  1.01800  0.612 22.15043 ? 274 ARG A HH21 1 
ATOM   4080 H  HH22 A ARG A 1 251 ? -7.11300  -4.44700  4.66600  0.388 23.50147 ? 274 ARG A HH22 1 
ATOM   4081 H  HH22 B ARG A 1 251 ? -8.45600  -5.56800  1.41500  0.612 22.15043 ? 274 ARG A HH22 1 
ATOM   4082 N  N    . ASP A 1 252 ? -4.72500  -12.38900 0.66100  1.000 12.62803 ? 275 ASP A N    1 
ATOM   4083 C  CA   . ASP A 1 252 ? -4.61300  -13.61700 -0.12000 1.000 13.33287 ? 275 ASP A CA   1 
ATOM   4084 C  C    . ASP A 1 252 ? -3.44100  -14.48300 0.33200  1.000 12.97888 ? 275 ASP A C    1 
ATOM   4085 O  O    . ASP A 1 252 ? -3.50400  -15.71200 0.22300  1.000 13.53631 ? 275 ASP A O    1 
ATOM   4086 C  CB   . ASP A 1 252 ? -4.44300  -13.28300 -1.60800 1.000 15.06743 ? 275 ASP A CB   1 
ATOM   4087 C  CG   . ASP A 1 252 ? -3.15700  -12.53400 -1.88500 1.000 17.01716 ? 275 ASP A CG   1 
ATOM   4088 O  OD1  . ASP A 1 252 ? -3.01400  -11.39600 -1.38200 1.000 16.59254 ? 275 ASP A OD1  1 
ATOM   4089 O  OD2  . ASP A 1 252 ? -2.27200  -13.10400 -2.55800 1.000 18.93974 ? 275 ASP A OD2  1 
ATOM   4090 H  H    . ASP A 1 252 ? -4.66900  -11.66500 0.19900  1.000 15.15168 ? 275 ASP A H    1 
ATOM   4091 H  HA   . ASP A 1 252 ? -5.43300  -14.12200 0.00200  1.000 15.99749 ? 275 ASP A HA   1 
ATOM   4092 H  HB2  . ASP A 1 252 ? -4.42800  -14.10800 -2.11900 1.000 18.07896 ? 275 ASP A HB2  1 
ATOM   4093 H  HB3  . ASP A 1 252 ? -5.18400  -12.72800 -1.89600 1.000 18.07896 ? 275 ASP A HB3  1 
ATOM   4094 N  N    . VAL A 1 253 ? -2.35700  -13.87400 0.81400  1.000 11.94278 ? 276 VAL A N    1 
ATOM   4095 C  CA   . VAL A 1 253 ? -1.21500  -14.65200 1.28600  1.000 12.50409 ? 276 VAL A CA   1 
ATOM   4096 C  C    . VAL A 1 253 ? -1.60600  -15.46000 2.51900  1.000 11.96674 ? 276 VAL A C    1 
ATOM   4097 O  O    . VAL A 1 253 ? -1.19200  -16.62000 2.67800  1.000 11.98292 ? 276 VAL A O    1 
ATOM   4098 C  CB   . VAL A 1 253 ? -0.00800  -13.72900 1.54200  1.000 12.82059 ? 276 VAL A CB   1 
ATOM   4099 C  CG1  . VAL A 1 253 ? 1.12400   -14.46900 2.24500  1.000 13.62230 ? 276 VAL A CG1  1 
ATOM   4100 C  CG2  . VAL A 1 253 ? 0.50000   -13.13400 0.22700  1.000 13.77732 ? 276 VAL A CG2  1 
ATOM   4101 H  H    . VAL A 1 253 ? -2.25900  -13.02200 0.87800  1.000 14.32939 ? 276 VAL A H    1 
ATOM   4102 H  HA   . VAL A 1 253 ? -0.95200  -15.28100 0.59600  1.000 15.00296 ? 276 VAL A HA   1 
ATOM   4103 H  HB   . VAL A 1 253 ? -0.30100  -13.00900 2.12300  1.000 15.38275 ? 276 VAL A HB   1 
ATOM   4104 H  HG11 . VAL A 1 253 ? 1.88900   -13.87800 2.32100  1.000 16.34481 ? 276 VAL A HG11 1 
ATOM   4105 H  HG12 . VAL A 1 253 ? 0.82500   -14.73800 3.12800  1.000 16.34481 ? 276 VAL A HG12 1 
ATOM   4106 H  HG13 . VAL A 1 253 ? 1.36200   -15.25200 1.72300  1.000 16.34481 ? 276 VAL A HG13 1 
ATOM   4107 H  HG21 . VAL A 1 253 ? 1.24000   -12.53600 0.41600  1.000 16.53083 ? 276 VAL A HG21 1 
ATOM   4108 H  HG22 . VAL A 1 253 ? 0.79500   -13.85400 -0.35200 1.000 16.53083 ? 276 VAL A HG22 1 
ATOM   4109 H  HG23 . VAL A 1 253 ? -0.22200  -12.64300 -0.19700 1.000 16.53083 ? 276 VAL A HG23 1 
ATOM   4110 N  N    . LEU A 1 254 ? -2.41700  -14.86300 3.40600  1.000 11.24314 ? 277 LEU A N    1 
ATOM   4111 C  CA   . LEU A 1 254 ? -2.86000  -15.57200 4.60400  1.000 10.31130 ? 277 LEU A CA   1 
ATOM   4112 C  C    . LEU A 1 254 ? -3.78300  -16.72200 4.22200  1.000 11.30853 ? 277 LEU A C    1 
ATOM   4113 O  O    . LEU A 1 254 ? -3.68100  -17.82500 4.77300  1.000 11.10190 ? 277 LEU A O    1 
ATOM   4114 C  CB   . LEU A 1 254 ? -3.57400  -14.61300 5.55900  1.000 10.87553 ? 277 LEU A CB   1 
ATOM   4115 C  CG   . LEU A 1 254 ? -2.80200  -13.34000 5.90300  1.000 10.51610 ? 277 LEU A CG   1 
ATOM   4116 C  CD1  . LEU A 1 254 ? -3.57300  -12.58500 6.98900  1.000 11.40521 ? 277 LEU A CD1  1 
ATOM   4117 C  CD2  . LEU A 1 254 ? -1.36700  -13.60200 6.33000  1.000 11.08846 ? 277 LEU A CD2  1 
ATOM   4118 H  H    . LEU A 1 254 ? -2.71800  -14.06000 3.33400  1.000 13.48982 ? 277 LEU A H    1 
ATOM   4119 H  HA   . LEU A 1 254 ? -2.08600  -15.92700 5.06800  1.000 12.37162 ? 277 LEU A HA   1 
ATOM   4120 H  HB2  . LEU A 1 254 ? -4.41200  -14.34300 5.15100  1.000 13.04868 ? 277 LEU A HB2  1 
ATOM   4121 H  HB3  . LEU A 1 254 ? -3.74600  -15.08100 6.39100  1.000 13.04868 ? 277 LEU A HB3  1 
ATOM   4122 H  HG   . LEU A 1 254 ? -2.72800  -12.79400 5.10500  1.000 12.61737 ? 277 LEU A HG   1 
ATOM   4123 H  HD11 . LEU A 1 254 ? -3.08500  -11.78000 7.22200  1.000 13.68430 ? 277 LEU A HD11 1 
ATOM   4124 H  HD12 . LEU A 1 254 ? -4.45100  -12.35200 6.64800  1.000 13.68430 ? 277 LEU A HD12 1 
ATOM   4125 H  HD13 . LEU A 1 254 ? -3.66200  -13.15600 7.76800  1.000 13.68430 ? 277 LEU A HD13 1 
ATOM   4126 H  HD21 . LEU A 1 254 ? -0.94000  -12.75700 6.54000  1.000 13.30420 ? 277 LEU A HD21 1 
ATOM   4127 H  HD22 . LEU A 1 254 ? -1.37000  -14.17500 7.11300  1.000 13.30420 ? 277 LEU A HD22 1 
ATOM   4128 H  HD23 . LEU A 1 254 ? -0.89600  -14.03900 5.60300  1.000 13.30420 ? 277 LEU A HD23 1 
ATOM   4129 N  N    . ALA A 1 255 ? -4.69600  -16.47500 3.28100  1.000 11.19923 ? 278 ALA A N    1 
ATOM   4130 C  CA   . ALA A 1 255 ? -5.56900  -17.53100 2.79400  1.000 11.43956 ? 278 ALA A CA   1 
ATOM   4131 C  C    . ALA A 1 255 ? -4.76000  -18.67700 2.19800  1.000 11.49195 ? 278 ALA A C    1 
ATOM   4132 O  O    . ALA A 1 255 ? -5.03900  -19.85300 2.46000  1.000 12.14959 ? 278 ALA A O    1 
ATOM   4133 C  CB   . ALA A 1 255 ? -6.54800  -16.94300 1.77700  1.000 11.76999 ? 278 ALA A CB   1 
ATOM   4134 H  H    . ALA A 1 255 ? -4.82600  -15.70900 2.91400  1.000 13.43713 ? 278 ALA A H    1 
ATOM   4135 H  HA   . ALA A 1 255 ? -6.08700  -17.89700 3.52800  1.000 13.72552 ? 278 ALA A HA   1 
ATOM   4136 H  HB1  . ALA A 1 255 ? -7.14900  -17.64200 1.47600  1.000 14.12204 ? 278 ALA A HB1  1 
ATOM   4137 H  HB2  . ALA A 1 255 ? -7.05400  -16.23200 2.20000  1.000 14.12204 ? 278 ALA A HB2  1 
ATOM   4138 H  HB3  . ALA A 1 255 ? -6.04700  -16.59000 1.02400  1.000 14.12204 ? 278 ALA A HB3  1 
ATOM   4139 N  N    . SER A 1 256 ? -3.75500  -18.35200 1.38800  1.000 11.94712 ? 279 SER A N    1 
ATOM   4140 C  CA   . SER A 1 256 ? -2.92200  -19.38000 0.77800  1.000 13.02226 ? 279 SER A CA   1 
ATOM   4141 C  C    . SER A 1 256 ? -2.17400  -20.18500 1.83300  1.000 12.43872 ? 279 SER A C    1 
ATOM   4142 O  O    . SER A 1 256 ? -2.06500  -21.41300 1.72900  1.000 13.46465 ? 279 SER A O    1 
ATOM   4143 C  CB   . SER A 1 256 ? -1.92400  -18.72900 -0.17400 1.000 13.72020 ? 279 SER A CB   1 
ATOM   4144 O  OG   . SER A 1 256 ? -2.56100  -18.18700 -1.31600 1.000 17.25096 ? 279 SER A OG   1 
ATOM   4145 H  H    . SER A 1 256 ? -3.53600  -17.54800 1.17700  1.000 14.33460 ? 279 SER A H    1 
ATOM   4146 H  HA   . SER A 1 256 ? -3.48900  -19.98600 0.27500  1.000 15.62476 ? 279 SER A HA   1 
ATOM   4147 H  HB2  . SER A 1 256 ? -1.46600  -18.01500 0.29600  1.000 16.46229 ? 279 SER A HB2  1 
ATOM   4148 H  HB3  . SER A 1 256 ? -1.28600  -19.40000 -0.46300 1.000 16.46229 ? 279 SER A HB3  1 
ATOM   4149 H  HG   . SER A 1 256 ? -2.99800  -17.50200 -1.10300 1.000 20.69921 ? 279 SER A HG   1 
ATOM   4150 N  N    . ALA A 1 257 ? -1.64000  -19.51000 2.85600  1.000 12.34087 ? 280 ALA A N    1 
ATOM   4151 C  CA   . ALA A 1 257 ? -0.93900  -20.22500 3.91700  1.000 12.35871 ? 280 ALA A CA   1 
ATOM   4152 C  C    . ALA A 1 257 ? -1.88400  -21.16300 4.65600  1.000 11.26618 ? 280 ALA A C    1 
ATOM   4153 O  O    . ALA A 1 257 ? -1.51700  -22.30200 4.97100  1.000 11.72191 ? 280 ALA A O    1 
ATOM   4154 C  CB   . ALA A 1 257 ? -0.31800  -19.22400 4.88900  1.000 12.66044 ? 280 ALA A CB   1 
ATOM   4155 H  H    . ALA A 1 257 ? -1.66900  -18.65600 2.95400  1.000 14.80710 ? 280 ALA A H    1 
ATOM   4156 H  HA   . ALA A 1 257 ? -0.22700  -20.75600 3.52700  1.000 14.82850 ? 280 ALA A HA   1 
ATOM   4157 H  HB1  . ALA A 1 257 ? 0.10600   -19.71000 5.61400  1.000 15.19058 ? 280 ALA A HB1  1 
ATOM   4158 H  HB2  . ALA A 1 257 ? 0.34300   -18.69400 4.41600  1.000 15.19058 ? 280 ALA A HB2  1 
ATOM   4159 H  HB3  . ALA A 1 257 ? -1.01600  -18.64900 5.23900  1.000 15.19058 ? 280 ALA A HB3  1 
ATOM   4160 N  N    . ALA A 1 258 ? -3.10400  -20.69600 4.93700  1.000 11.22049 ? 281 ALA A N    1 
ATOM   4161 C  CA   . ALA A 1 258 ? -4.08600  -21.53100 5.61900  1.000 11.62489 ? 281 ALA A CA   1 
ATOM   4162 C  C    . ALA A 1 258 ? -4.41200  -22.76900 4.80500  1.000 12.20485 ? 281 ALA A C    1 
ATOM   4163 O  O    . ALA A 1 258 ? -4.52500  -23.86700 5.35800  1.000 12.64440 ? 281 ALA A O    1 
ATOM   4164 C  CB   . ALA A 1 258 ? -5.35700  -20.72500 5.88000  1.000 11.48623 ? 281 ALA A CB   1 
ATOM   4165 H  H    . ALA A 1 258 ? -3.38400  -19.90500 4.74400  1.000 13.46264 ? 281 ALA A H    1 
ATOM   4166 H  HA   . ALA A 1 258 ? -3.71800  -21.81500 6.47100  1.000 13.94792 ? 281 ALA A HA   1 
ATOM   4167 H  HB1  . ALA A 1 258 ? -5.99200  -21.28300 6.35600  1.000 13.78152 ? 281 ALA A HB1  1 
ATOM   4168 H  HB2  . ALA A 1 258 ? -5.13400  -19.94800 6.41600  1.000 13.78152 ? 281 ALA A HB2  1 
ATOM   4169 H  HB3  . ALA A 1 258 ? -5.73400  -20.44500 5.03100  1.000 13.78152 ? 281 ALA A HB3  1 
ATOM   4170 N  N    . LYS A 1 259 ? -4.58300  -22.60800 3.48900  1.000 12.05356 ? 282 LYS A N    1 
ATOM   4171 C  CA   . LYS A 1 259 ? -4.85200  -23.75900 2.63300  1.000 13.27808 ? 282 LYS A CA   1 
ATOM   4172 C  C    . LYS A 1 259 ? -3.68900  -24.74000 2.65600  1.000 13.42000 ? 282 LYS A C    1 
ATOM   4173 O  O    . LYS A 1 259 ? -3.88800  -25.95300 2.76000  1.000 14.04803 ? 282 LYS A O    1 
ATOM   4174 C  CB   . LYS A 1 259 ? -5.13400  -23.28600 1.20700  1.000 14.84031 ? 282 LYS A CB   1 
ATOM   4175 C  CG   . LYS A 1 259 ? -5.43700  -24.42900 0.24600  1.000 19.03773 ? 282 LYS A CG   1 
ATOM   4176 C  CD   . LYS A 1 259 ? -5.87700  -23.92600 -1.12300 1.000 24.23239 ? 282 LYS A CD   1 
ATOM   4177 C  CE   . LYS A 1 259 ? -6.21900  -25.09600 -2.04800 1.000 29.24475 ? 282 LYS A CE   1 
ATOM   4178 N  NZ   . LYS A 1 259 ? -6.56700  -24.67400 -3.43900 1.000 33.20928 ? 282 LYS A NZ   1 
ATOM   4179 H  H    . LYS A 1 259 ? -4.54800  -21.85400 3.07600  1.000 14.46232 ? 282 LYS A H    1 
ATOM   4180 H  HA   . LYS A 1 259 ? -5.64000  -24.22300 2.95800  1.000 15.93175 ? 282 LYS A HA   1 
ATOM   4181 H  HB2  . LYS A 1 259 ? -5.90200  -22.69400 1.21800  1.000 17.80642 ? 282 LYS A HB2  1 
ATOM   4182 H  HB3  . LYS A 1 259 ? -4.35500  -22.81400 0.87300  1.000 17.80642 ? 282 LYS A HB3  1 
ATOM   4183 H  HG2  . LYS A 1 259 ? -4.63900  -24.96700 0.12800  1.000 22.84332 ? 282 LYS A HG2  1 
ATOM   4184 H  HG3  . LYS A 1 259 ? -6.15200  -24.97200 0.61200  1.000 22.84332 ? 282 LYS A HG3  1 
ATOM   4185 H  HD2  . LYS A 1 259 ? -6.66600  -23.37000 -1.02500 1.000 29.07691 ? 282 LYS A HD2  1 
ATOM   4186 H  HD3  . LYS A 1 259 ? -5.15800  -23.41400 -1.52600 1.000 29.07691 ? 282 LYS A HD3  1 
ATOM   4187 H  HE2  . LYS A 1 259 ? -5.45300  -25.68800 -2.10000 1.000 35.09175 ? 282 LYS A HE2  1 
ATOM   4188 H  HE3  . LYS A 1 259 ? -6.98100  -25.57200 -1.68300 1.000 35.09175 ? 282 LYS A HE3  1 
ATOM   4189 H  HZ1  . LYS A 1 259 ? -6.86700  -25.37200 -3.90300 1.000 39.84919 ? 282 LYS A HZ1  1 
ATOM   4190 H  HZ2  . LYS A 1 259 ? -7.19900  -24.04800 -3.41800 1.000 39.84919 ? 282 LYS A HZ2  1 
ATOM   4191 H  HZ3  . LYS A 1 259 ? -5.84800  -24.34400 -3.84600 1.000 39.84919 ? 282 LYS A HZ3  1 
ATOM   4192 N  N    . ILE A 1 260 ? -2.46200  -24.23400 2.56500  1.000 13.07637 ? 283 ILE A N    1 
ATOM   4193 C  CA   . ILE A 1 260 ? -1.29200  -25.10600 2.53800  1.000 12.93191 ? 283 ILE A CA   1 
ATOM   4194 C  C    . ILE A 1 260 ? -1.22000  -25.95800 3.80100  1.000 12.94036 ? 283 ILE A C    1 
ATOM   4195 O  O    . ILE A 1 260 ? -0.95000  -27.16100 3.73700  1.000 14.32499 ? 283 ILE A O    1 
ATOM   4196 C  CB   . ILE A 1 260 ? -0.01500  -24.26900 2.32700  1.000 13.73971 ? 283 ILE A CB   1 
ATOM   4197 C  CG1  . ILE A 1 260 ? 0.04000   -23.76900 0.87600  1.000 14.60598 ? 283 ILE A CG1  1 
ATOM   4198 C  CG2  . ILE A 1 260 ? 1.24100   -25.05300 2.68900  1.000 14.15984 ? 283 ILE A CG2  1 
ATOM   4199 C  CD1  . ILE A 1 260 ? 1.01200   -22.63000 0.66800  1.000 15.55761 ? 283 ILE A CD1  1 
ATOM   4200 H  H    . ILE A 1 260 ? -2.28000  -23.39500 2.51800  1.000 15.68969 ? 283 ILE A H    1 
ATOM   4201 H  HA   . ILE A 1 260 ? -1.37800  -25.71600 1.78900  1.000 15.51634 ? 283 ILE A HA   1 
ATOM   4202 H  HB   . ILE A 1 260 ? -0.05100  -23.50600 2.92400  1.000 16.48570 ? 283 ILE A HB   1 
ATOM   4203 H  HG12 . ILE A 1 260 ? 0.31300   -24.50200 0.30200  1.000 17.52522 ? 283 ILE A HG12 1 
ATOM   4204 H  HG13 . ILE A 1 260 ? -0.84200  -23.45700 0.61800  1.000 17.52522 ? 283 ILE A HG13 1 
ATOM   4205 H  HG21 . ILE A 1 260 ? 2.02000   -24.55200 2.39900  1.000 16.98985 ? 283 ILE A HG21 1 
ATOM   4206 H  HG22 . ILE A 1 260 ? 1.26900   -25.17900 3.65000  1.000 16.98985 ? 283 ILE A HG22 1 
ATOM   4207 H  HG23 . ILE A 1 260 ? 1.21600   -25.91400 2.24300  1.000 16.98985 ? 283 ILE A HG23 1 
ATOM   4208 H  HD11 . ILE A 1 260 ? 0.96700   -22.34100 -0.25700 1.000 18.66718 ? 283 ILE A HD11 1 
ATOM   4209 H  HD12 . ILE A 1 260 ? 0.77000   -21.89700 1.25600  1.000 18.66718 ? 283 ILE A HD12 1 
ATOM   4210 H  HD13 . ILE A 1 260 ? 1.90800   -22.93800 0.87500  1.000 18.66718 ? 283 ILE A HD13 1 
ATOM   4211 N  N    . VAL A 1 261 ? -1.41900  -25.34800 4.97400  1.000 13.00180 ? 284 VAL A N    1 
ATOM   4212 C  CA   . VAL A 1 261 ? -1.17700  -26.07900 6.21600  1.000 13.38634 ? 284 VAL A CA   1 
ATOM   4213 C  C    . VAL A 1 261 ? -2.35200  -26.94500 6.64000  1.000 14.68848 ? 284 VAL A C    1 
ATOM   4214 O  O    . VAL A 1 261 ? -2.19100  -27.77000 7.54700  1.000 16.33371 ? 284 VAL A O    1 
ATOM   4215 C  CB   . VAL A 1 261 ? -0.71700  -25.17500 7.37900  1.000 13.14816 ? 284 VAL A CB   1 
ATOM   4216 C  CG1  . VAL A 1 261 ? 0.53200   -24.40600 6.98500  1.000 14.32253 ? 284 VAL A CG1  1 
ATOM   4217 C  CG2  . VAL A 1 261 ? -1.83100  -24.22300 7.83600  1.000 13.75364 ? 284 VAL A CG2  1 
ATOM   4218 H  H    . VAL A 1 261 ? -1.68500  -24.53600 5.07200  1.000 15.60021 ? 284 VAL A H    1 
ATOM   4219 H  HA   . VAL A 1 261 ? -0.43100  -26.67400 6.04000  1.000 16.06165 ? 284 VAL A HA   1 
ATOM   4220 H  HB   . VAL A 1 261 ? -0.50300  -25.74100 8.13700  1.000 15.77584 ? 284 VAL A HB   1 
ATOM   4221 H  HG11 . VAL A 1 261 ? 0.84000   -23.89100 7.74800  1.000 17.18508 ? 284 VAL A HG11 1 
ATOM   4222 H  HG12 . VAL A 1 261 ? 1.21800   -25.03600 6.71300  1.000 17.18508 ? 284 VAL A HG12 1 
ATOM   4223 H  HG13 . VAL A 1 261 ? 0.31800   -23.81100 6.25000  1.000 17.18508 ? 284 VAL A HG13 1 
ATOM   4224 H  HG21 . VAL A 1 261 ? -1.47400  -23.61700 8.50400  1.000 16.50242 ? 284 VAL A HG21 1 
ATOM   4225 H  HG22 . VAL A 1 261 ? -2.15100  -23.72100 7.07000  1.000 16.50242 ? 284 VAL A HG22 1 
ATOM   4226 H  HG23 . VAL A 1 261 ? -2.55600  -24.74400 8.21500  1.000 16.50242 ? 284 VAL A HG23 1 
ATOM   4227 N  N    . THR A 1 262 ? -3.52300  -26.79600 6.01300  1.000 14.38124 ? 285 THR A N    1 
ATOM   4228 C  CA   . THR A 1 262 ? -4.67200  -27.63900 6.32500  1.000 16.52446 ? 285 THR A CA   1 
ATOM   4229 C  C    . THR A 1 262 ? -4.99600  -28.65000 5.23300  1.000 21.01639 ? 285 THR A C    1 
ATOM   4230 O  O    . THR A 1 262 ? -5.88300  -29.48600 5.43300  1.000 21.97259 ? 285 THR A O    1 
ATOM   4231 C  CB   . THR A 1 262 ? -5.92500  -26.80000 6.62400  1.000 15.88778 ? 285 THR A CB   1 
ATOM   4232 O  OG1  . THR A 1 262 ? -6.27200  -25.99500 5.49100  1.000 15.52664 ? 285 THR A OG1  1 
ATOM   4233 C  CG2  . THR A 1 262 ? -5.71000  -25.92500 7.85800  1.000 15.94708 ? 285 THR A CG2  1 
ATOM   4234 H  H    . THR A 1 262 ? -3.67400  -26.21100 5.40100  1.000 17.25554 ? 285 THR A H    1 
ATOM   4235 H  HA   . THR A 1 262 ? -4.46400  -28.12800 7.13600  1.000 19.82740 ? 285 THR A HA   1 
ATOM   4236 H  HB   . THR A 1 262 ? -6.66800  -27.39500 6.81000  1.000 19.06338 ? 285 THR A HB   1 
ATOM   4237 H  HG1  . THR A 1 262 ? -5.69300  -25.39800 5.37400  1.000 18.63002 ? 285 THR A HG1  1 
ATOM   4238 H  HG21 . THR A 1 262 ? -6.50900  -25.40700 8.04000  1.000 19.13455 ? 285 THR A HG21 1 
ATOM   4239 H  HG22 . THR A 1 262 ? -5.51300  -26.48100 8.62800  1.000 19.13455 ? 285 THR A HG22 1 
ATOM   4240 H  HG23 . THR A 1 262 ? -4.96800  -25.31900 7.70900  1.000 19.13455 ? 285 THR A HG23 1 
ATOM   4241 N  N    A ASP A 1 263 ? -4.30300  -28.60800 4.09900  0.724 24.92794 ? 286 ASP A N    1 
ATOM   4242 N  N    B ASP A 1 263 ? -4.32300  -28.58400 4.08500  0.276 24.98745 ? 286 ASP A N    1 
ATOM   4243 C  CA   A ASP A 1 263 ? -4.53800  -29.57900 3.04000  0.724 30.90943 ? 286 ASP A CA   1 
ATOM   4244 C  CA   B ASP A 1 263 ? -4.48500  -29.60000 3.05400  0.276 29.70250 ? 286 ASP A CA   1 
ATOM   4245 C  C    A ASP A 1 263 ? -4.25100  -30.99000 3.54300  0.724 33.82359 ? 286 ASP A C    1 
ATOM   4246 C  C    B ASP A 1 263 ? -4.28900  -30.98200 3.65700  0.276 33.35074 ? 286 ASP A C    1 
ATOM   4247 O  O    A ASP A 1 263 ? -3.16400  -31.27300 4.05100  0.724 34.73346 ? 286 ASP A O    1 
ATOM   4248 O  O    B ASP A 1 263 ? -3.31700  -31.22600 4.37700  0.276 33.69335 ? 286 ASP A O    1 
ATOM   4249 C  CB   A ASP A 1 263 ? -3.63700  -29.26100 1.85000  0.724 33.99515 ? 286 ASP A CB   1 
ATOM   4250 C  CB   B ASP A 1 263 ? -3.45000  -29.38000 1.95100  0.276 30.71831 ? 286 ASP A CB   1 
ATOM   4251 C  CG   A ASP A 1 263 ? -3.86000  -30.20300 0.69100  0.724 37.54418 ? 286 ASP A CG   1 
ATOM   4252 C  CG   B ASP A 1 263 ? -3.81200  -28.23900 1.03000  0.276 31.88385 ? 286 ASP A CG   1 
ATOM   4253 O  OD1  A ASP A 1 263 ? -4.90500  -30.07600 0.01900  0.724 39.03519 ? 286 ASP A OD1  1 
ATOM   4254 O  OD1  B ASP A 1 263 ? -4.98400  -28.16300 0.60600  0.276 32.10412 ? 286 ASP A OD1  1 
ATOM   4255 O  OD2  A ASP A 1 263 ? -2.99600  -31.07300 0.45900  0.724 39.31066 ? 286 ASP A OD2  1 
ATOM   4256 O  OD2  B ASP A 1 263 ? -2.92800  -27.41000 0.73600  0.276 32.61223 ? 286 ASP A OD2  1 
ATOM   4257 H  H    A ASP A 1 263 ? -3.69300  -28.02900 3.92000  0.724 29.91157 ? 286 ASP A H    1 
ATOM   4258 H  H    B ASP A 1 263 ? -3.76700  -27.96100 3.88100  0.276 29.98299 ? 286 ASP A H    1 
ATOM   4259 H  HA   A ASP A 1 263 ? -5.46500  -29.53500 2.75500  0.724 37.08937 ? 286 ASP A HA   1 
ATOM   4260 H  HA   B ASP A 1 263 ? -5.37300  -29.53800 2.66800  0.276 35.64105 ? 286 ASP A HA   1 
ATOM   4261 H  HB2  A ASP A 1 263 ? -3.82000  -28.35900 1.54500  0.724 40.79223 ? 286 ASP A HB2  1 
ATOM   4262 H  HB2  B ASP A 1 263 ? -2.59300  -29.17700 2.35800  0.276 36.86003 ? 286 ASP A HB2  1 
ATOM   4263 H  HB3  A ASP A 1 263 ? -2.71000  -29.33600 2.12600  0.724 40.79223 ? 286 ASP A HB3  1 
ATOM   4264 H  HB3  B ASP A 1 263 ? -3.38000  -30.18700 1.41600  0.276 36.86003 ? 286 ASP A HB3  1 
ATOM   4265 N  N    . GLY A 1 264 ? -5.23000  -31.88300 3.38400  1.000 36.92133 ? 287 GLY A N    1 
ATOM   4266 C  CA   . GLY A 1 264 ? -5.17600  -33.22900 3.90100  1.000 42.36475 ? 287 GLY A CA   1 
ATOM   4267 C  C    . GLY A 1 264 ? -6.08400  -33.44600 5.09600  1.000 47.06545 ? 287 GLY A C    1 
ATOM   4268 O  O    . GLY A 1 264 ? -6.52300  -34.57800 5.33300  1.000 47.80334 ? 287 GLY A O    1 
ATOM   4269 H  H    . GLY A 1 264 ? -5.96100  -31.71800 2.96200  1.000 44.30365 ? 287 GLY A H    1 
ATOM   4270 H  HA2  . GLY A 1 264 ? -5.44100  -33.84800 3.20300  1.000 50.83575 ? 287 GLY A HA2  1 
ATOM   4271 H  HA3  . GLY A 1 264 ? -4.26600  -33.42900 4.17200  1.000 50.83575 ? 287 GLY A HA3  1 
ATOM   4272 N  N    . LEU A 1 265 ? -6.36700  -32.39400 5.85700  1.000 49.89427 ? 288 LEU A N    1 
ATOM   4273 C  CA   . LEU A 1 265 ? -7.38600  -32.46500 6.89600  1.000 52.57882 ? 288 LEU A CA   1 
ATOM   4274 C  C    . LEU A 1 265 ? -8.74400  -32.22600 6.24000  1.000 54.48516 ? 288 LEU A C    1 
ATOM   4275 O  O    . LEU A 1 265 ? -8.85000  -31.48100 5.25800  1.000 55.38208 ? 288 LEU A O    1 
ATOM   4276 C  CB   . LEU A 1 265 ? -7.15700  -31.41100 7.97900  1.000 52.54890 ? 288 LEU A CB   1 
ATOM   4277 C  CG   . LEU A 1 265 ? -5.73300  -31.10700 8.44300  1.000 52.37435 ? 288 LEU A CG   1 
ATOM   4278 C  CD1  . LEU A 1 265 ? -5.73700  -29.80000 9.22200  1.000 52.00830 ? 288 LEU A CD1  1 
ATOM   4279 C  CD2  . LEU A 1 265 ? -5.16700  -32.22900 9.29300  1.000 52.52861 ? 288 LEU A CD2  1 
ATOM   4280 H  H    . LEU A 1 265 ? -5.98200  -31.62800 5.79100  1.000 59.87118 ? 288 LEU A H    1 
ATOM   4281 H  HA   . LEU A 1 265 ? -7.35700  -33.33000 7.33400  1.000 63.09263 ? 288 LEU A HA   1 
ATOM   4282 H  HB2  . LEU A 1 265 ? -7.52000  -30.57500 7.64800  1.000 63.05673 ? 288 LEU A HB2  1 
ATOM   4283 H  HB3  . LEU A 1 265 ? -7.64500  -31.69700 8.76700  1.000 63.05673 ? 288 LEU A HB3  1 
ATOM   4284 H  HG   . LEU A 1 265 ? -5.15500  -31.02400 7.66900  1.000 62.84727 ? 288 LEU A HG   1 
ATOM   4285 H  HD11 . LEU A 1 265 ? -4.85800  -29.65900 9.60700  1.000 62.40801 ? 288 LEU A HD11 1 
ATOM   4286 H  HD12 . LEU A 1 265 ? -5.95400  -29.07300 8.61800  1.000 62.40801 ? 288 LEU A HD12 1 
ATOM   4287 H  HD13 . LEU A 1 265 ? -6.40200  -29.85500 9.92600  1.000 62.40801 ? 288 LEU A HD13 1 
ATOM   4288 H  HD21 . LEU A 1 265 ? -4.28300  -31.97500 9.60300  1.000 63.03238 ? 288 LEU A HD21 1 
ATOM   4289 H  HD22 . LEU A 1 265 ? -5.75300  -32.37800 10.05100 1.000 63.03238 ? 288 LEU A HD22 1 
ATOM   4290 H  HD23 . LEU A 1 265 ? -5.11000  -33.03400 8.75500  1.000 63.03238 ? 288 LEU A HD23 1 
HETATM 4291 C  C1   A 6M9 B 2 .   ? -6.05700  -1.67800  12.72700 0.896 11.68244 ? 301 6M9 A C1   1 
HETATM 4292 C  C2   A 6M9 B 2 .   ? -5.17900  -0.62600  13.02200 0.896 12.55430 ? 301 6M9 A C2   1 
HETATM 4293 C  C3   A 6M9 B 2 .   ? -5.32700  0.62600   12.44600 0.896 13.74774 ? 301 6M9 A C3   1 
HETATM 4294 C  C4   A 6M9 B 2 .   ? -6.36100  0.86500   11.56300 0.896 13.62914 ? 301 6M9 A C4   1 
HETATM 4295 C  C5   A 6M9 B 2 .   ? -7.25100  -0.14500  11.25100 0.896 13.25267 ? 301 6M9 A C5   1 
HETATM 4296 C  C6   A 6M9 B 2 .   ? -7.09800  -1.40200  11.82600 0.896 12.70505 ? 301 6M9 A C6   1 
HETATM 4297 C  C7   A 6M9 B 2 .   ? -7.89300  -2.63600  11.54400 0.896 13.03684 ? 301 6M9 A C7   1 
HETATM 4298 O  O1   A 6M9 B 2 .   ? -7.27800  -3.70500  12.31600 0.896 12.53945 ? 301 6M9 A O1   1 
HETATM 4299 O  O2   A 6M9 B 2 .   ? -4.84400  -3.85900  12.55500 0.896 10.89178 ? 301 6M9 A O2   1 
HETATM 4300 B  B1   A 6M9 B 2 .   ? -6.08900  -3.21600  13.09700 0.896 11.60392 ? 301 6M9 A B1   1 
HETATM 4301 H  H1   A 6M9 B 2 .   ? -4.44600  -0.77700  13.65400 0.896 15.06321 ? 301 6M9 A H1   1 
HETATM 4302 H  H2   A 6M9 B 2 .   ? -4.69600  1.34200   12.66500 0.896 16.49534 ? 301 6M9 A H2   1 
HETATM 4303 H  H3   A 6M9 B 2 .   ? -6.46400  1.75100   11.15800 0.896 16.35302 ? 301 6M9 A H3   1 
HETATM 4304 H  H4   A 6M9 B 2 .   ? -7.98700  0.02500   10.62800 0.896 15.90125 ? 301 6M9 A H4   1 
HETATM 4305 H  H5   A 6M9 B 2 .   ? -7.86200  -2.85100  10.58900 0.896 15.64226 ? 301 6M9 A H5   1 
HETATM 4306 H  H6   A 6M9 B 2 .   ? -4.24900  -3.25200  12.55600 0.896 13.06818 ? 301 6M9 A H6   1 
HETATM 4307 H  H7   A 6M9 B 2 .   ? -8.82300  -2.51300  11.82300 0.896 15.64226 ? 301 6M9 A H7   1 
HETATM 4308 S  S    . DMS C 3 .   ? 12.37800  -13.05100 4.85800  0.776 22.02974 ? 302 DMS A S    1 
HETATM 4309 O  O    . DMS C 3 .   ? 11.95200  -13.41100 3.46100  0.776 23.35882 ? 302 DMS A O    1 
HETATM 4310 C  C1   . DMS C 3 .   ? 12.60700  -11.27500 5.02900  0.776 21.52434 ? 302 DMS A C1   1 
HETATM 4311 C  C2   . DMS C 3 .   ? 14.12600  -13.48900 5.05600  0.776 23.43503 ? 302 DMS A C2   1 
HETATM 4312 H  H11  . DMS C 3 .   ? 11.73200  -10.84400 5.44100  0.776 25.82726 ? 302 DMS A H11  1 
HETATM 4313 H  H12  . DMS C 3 .   ? 12.79600  -10.84900 4.07800  0.776 25.82726 ? 302 DMS A H12  1 
HETATM 4314 H  H13  . DMS C 3 .   ? 13.42900  -11.08400 5.67000  0.776 25.82726 ? 302 DMS A H13  1 
HETATM 4315 H  H21  . DMS C 3 .   ? 14.46500  -13.16800 6.00700  0.776 28.12008 ? 302 DMS A H21  1 
HETATM 4316 H  H22  . DMS C 3 .   ? 14.69800  -13.01500 4.30100  0.776 28.12008 ? 302 DMS A H22  1 
HETATM 4317 H  H23  . DMS C 3 .   ? 14.23900  -14.53900 4.97700  0.776 28.12008 ? 302 DMS A H23  1 
HETATM 4318 C  C1   . GOL D 4 .   ? -10.07600 -24.87300 0.61700  1.000 59.08456 ? 303 GOL A C1   1 
HETATM 4319 O  O1   . GOL D 4 .   ? -10.92000 -25.96400 0.42700  1.000 59.20148 ? 303 GOL A O1   1 
HETATM 4320 C  C2   . GOL D 4 .   ? -10.68000 -23.72700 -0.20400 1.000 59.20605 ? 303 GOL A C2   1 
HETATM 4321 O  O2   . GOL D 4 .   ? -12.00100 -23.51000 0.13400  1.000 59.29849 ? 303 GOL A O2   1 
HETATM 4322 C  C3   . GOL D 4 .   ? -9.79800  -22.49900 0.09200  1.000 59.46036 ? 303 GOL A C3   1 
HETATM 4323 O  O3   . GOL D 4 .   ? -9.70300  -21.77500 -1.10300 1.000 59.47532 ? 303 GOL A O3   1 
HETATM 4324 H  H11  . GOL D 4 .   ? -9.16800  -25.04300 0.32200  1.000 70.89952 ? 303 GOL A H11  1 
HETATM 4325 H  H12  . GOL D 4 .   ? -10.00800 -24.60700 1.54700  1.000 70.89952 ? 303 GOL A H12  1 
HETATM 4326 H  HO1  . GOL D 4 .   ? -11.56200 -25.87200 0.97400  1.000 71.03983 ? 303 GOL A HO1  1 
HETATM 4327 H  H2   . GOL D 4 .   ? -10.66200 -23.93700 -1.15100 1.000 71.04532 ? 303 GOL A H2   1 
HETATM 4328 H  HO2  . GOL D 4 .   ? -12.11500 -23.78100 0.92900  1.000 71.15624 ? 303 GOL A HO2  1 
HETATM 4329 H  H31  . GOL D 4 .   ? -8.94000  -22.80100 0.42900  1.000 71.35048 ? 303 GOL A H31  1 
HETATM 4330 H  H32  . GOL D 4 .   ? -10.19500 -21.99400 0.81900  1.000 71.35048 ? 303 GOL A H32  1 
HETATM 4331 H  HO3  . GOL D 4 .   ? -10.49500 -21.56700 -1.33000 1.000 71.36843 ? 303 GOL A HO3  1 
HETATM 4332 S  S    . DMS E 3 .   ? 11.70900  -7.12600  14.56300 1.000 38.95738 ? 304 DMS A S    1 
HETATM 4333 O  O    . DMS E 3 .   ? 10.23900  -7.11700  14.26500 1.000 38.79598 ? 304 DMS A O    1 
HETATM 4334 C  C1   . DMS E 3 .   ? 11.91900  -7.54500  16.31700 1.000 37.19236 ? 304 DMS A C1   1 
HETATM 4335 C  C2   . DMS E 3 .   ? 12.40500  -8.64400  13.85300 1.000 39.41586 ? 304 DMS A C2   1 
HETATM 4336 H  H11  . DMS E 3 .   ? 12.56100  -8.38200  16.40600 1.000 44.62888 ? 304 DMS A H11  1 
HETATM 4337 H  H12  . DMS E 3 .   ? 10.97600  -7.77700  16.74000 1.000 44.62888 ? 304 DMS A H12  1 
HETATM 4338 H  H13  . DMS E 3 .   ? 12.34100  -6.72000  16.82900 1.000 44.62888 ? 304 DMS A H13  1 
HETATM 4339 H  H21  . DMS E 3 .   ? 13.37300  -8.80900  14.25000 1.000 47.29708 ? 304 DMS A H21  1 
HETATM 4340 H  H22  . DMS E 3 .   ? 12.46800  -8.54600  12.80000 1.000 47.29708 ? 304 DMS A H22  1 
HETATM 4341 H  H23  . DMS E 3 .   ? 11.78100  -9.46500  14.09300 1.000 47.29708 ? 304 DMS A H23  1 
HETATM 4342 S  S    . SO4 F 5 .   ? -15.23300 7.18000   31.72000 0.677 39.65376 ? 305 SO4 A S    1 
HETATM 4343 O  O1   . SO4 F 5 .   ? -14.39900 6.64000   30.65800 0.677 41.17611 ? 305 SO4 A O1   1 
HETATM 4344 O  O2   . SO4 F 5 .   ? -16.63300 6.97300   31.37200 0.677 40.78470 ? 305 SO4 A O2   1 
HETATM 4345 O  O3   . SO4 F 5 .   ? -14.94300 6.45700   32.96000 0.677 39.95333 ? 305 SO4 A O3   1 
HETATM 4346 O  O4   . SO4 F 5 .   ? -14.95600 8.60300   31.91200 0.677 41.50568 ? 305 SO4 A O4   1 
HETATM 4347 S  S    . SO4 G 5 .   ? 16.12300  -16.90900 5.84600  1.000 70.70245 ? 306 SO4 A S    1 
HETATM 4348 O  O1   . SO4 G 5 .   ? 16.37000  -15.51300 5.49600  1.000 71.81053 ? 306 SO4 A O1   1 
HETATM 4349 O  O2   . SO4 G 5 .   ? 15.17600  -17.48800 4.89700  1.000 70.26891 ? 306 SO4 A O2   1 
HETATM 4350 O  O3   . SO4 G 5 .   ? 15.58200  -16.97900 7.19900  1.000 70.35251 ? 306 SO4 A O3   1 
HETATM 4351 O  O4   . SO4 G 5 .   ? 17.38800  -17.63900 5.78900  1.000 70.76737 ? 306 SO4 A O4   1 
HETATM 4352 S  S    . SO4 H 5 .   ? 9.33000   -8.13900  29.86700 1.000 32.01384 ? 307 SO4 A S    1 
HETATM 4353 O  O1   . SO4 H 5 .   ? 10.76600  -7.84500  29.94400 1.000 33.17140 ? 307 SO4 A O1   1 
HETATM 4354 O  O2   . SO4 H 5 .   ? 8.80400   -7.84400  28.53200 1.000 30.80938 ? 307 SO4 A O2   1 
HETATM 4355 O  O3   . SO4 H 5 .   ? 9.10800   -9.54400  30.20300 1.000 32.84818 ? 307 SO4 A O3   1 
HETATM 4356 O  O4   . SO4 H 5 .   ? 8.65900   -7.26800  30.83700 1.000 35.45216 ? 307 SO4 A O4   1 
HETATM 4357 S  S    A SO4 I 5 .   ? 6.04500   6.57500   18.56200 0.447 18.30112 ? 308 SO4 A S    1 
HETATM 4358 O  O1   A SO4 I 5 .   ? 5.80500   7.94300   18.11700 0.447 19.29851 ? 308 SO4 A O1   1 
HETATM 4359 O  O2   A SO4 I 5 .   ? 5.22700   5.64100   17.79000 0.447 18.05445 ? 308 SO4 A O2   1 
HETATM 4360 O  O3   A SO4 I 5 .   ? 5.69600   6.45200   19.97400 0.447 19.19624 ? 308 SO4 A O3   1 
HETATM 4361 O  O4   A SO4 I 5 .   ? 7.46600   6.25700   18.38000 0.447 18.86734 ? 308 SO4 A O4   1 
HETATM 4362 S  S    A SO4 J 5 .   ? -7.01000  -2.76100  2.17200  0.590 49.52154 ? 309 SO4 A S    1 
HETATM 4363 O  O1   A SO4 J 5 .   ? -6.33400  -3.62100  1.20600  0.590 49.26776 ? 309 SO4 A O1   1 
HETATM 4364 O  O2   A SO4 J 5 .   ? -6.60300  -1.37600  1.96000  0.590 49.55725 ? 309 SO4 A O2   1 
HETATM 4365 O  O3   A SO4 J 5 .   ? -6.64700  -3.16200  3.52700  0.590 49.64595 ? 309 SO4 A O3   1 
HETATM 4366 O  O4   A SO4 J 5 .   ? -8.45400  -2.87800  1.99500  0.590 49.64413 ? 309 SO4 A O4   1 
HETATM 4367 CL CL   . CL  K 6 .   ? -15.72000 -25.49300 0.30100  1.000 15.26084 ? 310 CL  A CL   1 
HETATM 4368 NA NA   . NA  L 7 .   ? 1.80100   -13.82600 21.83800 1.000 16.13866 ? 311 NA  A NA   1 
HETATM 4369 NA NA   . NA  M 7 .   ? -10.29200 -15.59400 8.91500  1.000 15.61771 ? 312 NA  A NA   1 
HETATM 4370 NA NA   A NA  N 7 .   ? -7.71300  -5.87000  10.83600 0.905 27.20239 ? 313 NA  A NA   1 
HETATM 4371 S  S    B SO4 O 5 .   ? -7.78000  -4.96800  10.55100 0.104 14.99528 ? 314 SO4 A S    1 
HETATM 4372 O  O1   B SO4 O 5 .   ? -6.95700  -6.09500  10.15300 0.104 15.06308 ? 314 SO4 A O1   1 
HETATM 4373 O  O2   B SO4 O 5 .   ? -7.67500  -3.91000  9.55400  0.104 16.15929 ? 314 SO4 A O2   1 
HETATM 4374 O  O3   B SO4 O 5 .   ? -9.14900  -5.44800  10.67100 0.104 16.78707 ? 314 SO4 A O3   1 
HETATM 4375 O  O4   B SO4 O 5 .   ? -7.37900  -4.47100  11.88100 0.104 17.04759 ? 314 SO4 A O4   1 
HETATM 4376 O  O    . HOH P 8 .   ? -1.74500  -27.17400 -0.73000 1.000 38.40428 ? 401 HOH A O    1 
HETATM 4377 O  O    . HOH P 8 .   ? -6.32700  -27.37700 1.94800  1.000 47.99658 ? 402 HOH A O    1 
HETATM 4378 O  O    . HOH P 8 .   ? -16.51000 -17.98900 9.76100  1.000 42.27029 ? 403 HOH A O    1 
HETATM 4379 O  O    . HOH P 8 .   ? -17.66500 -5.58100  39.92700 1.000 35.55679 ? 404 HOH A O    1 
HETATM 4380 O  O    . HOH P 8 .   ? -19.15700 11.05200  26.56900 1.000 33.34328 ? 405 HOH A O    1 
HETATM 4381 O  O    . HOH P 8 .   ? -15.11000 -3.56500  38.91300 1.000 44.47929 ? 406 HOH A O    1 
HETATM 4382 O  O    . HOH P 8 .   ? 4.27800   -23.27900 -4.76100 1.000 39.83364 ? 407 HOH A O    1 
HETATM 4383 O  O    . HOH P 8 .   ? -11.99600 -22.38400 32.38400 1.000 33.02781 ? 408 HOH A O    1 
HETATM 4384 O  O    . HOH P 8 .   ? -6.09900  -27.91300 23.59100 1.000 39.66753 ? 409 HOH A O    1 
HETATM 4385 O  O    A HOH P 8 .   ? -13.85800 7.76600   28.45700 0.449 14.74083 ? 410 HOH A O    1 
HETATM 4386 O  O    B HOH P 8 .   ? -12.96000 7.14700   29.52300 0.551 25.95212 ? 410 HOH A O    1 
HETATM 4387 O  O    . HOH P 8 .   ? 5.58000   -32.81800 5.81200  1.000 66.20283 ? 411 HOH A O    1 
HETATM 4388 O  O    A HOH P 8 .   ? -2.54800  -29.69500 21.31700 0.538 16.65798 ? 412 HOH A O    1 
HETATM 4389 O  O    . HOH P 8 .   ? -5.85100  -16.18300 33.59700 1.000 74.63105 ? 413 HOH A O    1 
HETATM 4390 O  O    . HOH P 8 .   ? 0.84800   -28.66100 22.64000 1.000 58.46918 ? 414 HOH A O    1 
HETATM 4391 O  O    . HOH P 8 .   ? -10.30400 -7.71400  39.24400 1.000 37.68730 ? 415 HOH A O    1 
HETATM 4392 O  O    . HOH P 8 .   ? -15.41500 3.50800   33.24300 1.000 45.27833 ? 416 HOH A O    1 
HETATM 4393 O  O    . HOH P 8 .   ? -4.20800  -2.36700  16.00000 1.000 12.36033 ? 417 HOH A O    1 
HETATM 4394 O  O    . HOH P 8 .   ? 8.63700   -5.70100  32.86300 1.000 42.88216 ? 418 HOH A O    1 
HETATM 4395 O  O    . HOH P 8 .   ? -9.14700  10.40500  25.61700 1.000 37.26422 ? 419 HOH A O    1 
HETATM 4396 O  O    . HOH P 8 .   ? -17.76300 13.17700  16.43400 1.000 56.58340 ? 420 HOH A O    1 
HETATM 4397 O  O    . HOH P 8 .   ? -14.37100 8.22800   12.84100 1.000 24.84058 ? 421 HOH A O    1 
HETATM 4398 O  O    . HOH P 8 .   ? -23.45200 -3.97600  27.60000 1.000 33.39276 ? 422 HOH A O    1 
HETATM 4399 O  O    . HOH P 8 .   ? -5.72800  -17.90200 34.37000 1.000 35.36325 ? 423 HOH A O    1 
HETATM 4400 O  O    . HOH P 8 .   ? -18.48100 -27.78400 10.18800 1.000 35.20080 ? 424 HOH A O    1 
HETATM 4401 O  O    . HOH P 8 .   ? -15.38800 -20.46100 7.76100  1.000 33.70161 ? 425 HOH A O    1 
HETATM 4402 O  O    . HOH P 8 .   ? -19.47100 3.73800   11.19900 1.000 31.30962 ? 426 HOH A O    1 
HETATM 4403 O  O    . HOH P 8 .   ? -21.49400 -18.35800 24.16700 1.000 50.84659 ? 427 HOH A O    1 
HETATM 4404 O  O    B HOH P 8 .   ? -0.19500  -26.90200 22.71000 0.558 22.40127 ? 428 HOH A O    1 
HETATM 4405 O  O    . HOH P 8 .   ? 3.48400   -31.33600 11.69600 1.000 43.31858 ? 429 HOH A O    1 
HETATM 4406 O  O    . HOH P 8 .   ? -20.22900 -6.07000  17.86100 1.000 42.60334 ? 430 HOH A O    1 
HETATM 4407 O  O    . HOH P 8 .   ? -14.04800 -0.28500  7.12400  1.000 45.41387 ? 431 HOH A O    1 
HETATM 4408 O  O    . HOH P 8 .   ? -17.79800 -14.36700 11.51500 1.000 56.42730 ? 432 HOH A O    1 
HETATM 4409 O  O    . HOH P 8 .   ? 7.94800   5.48800   15.90500 1.000 38.35092 ? 433 HOH A O    1 
HETATM 4410 O  O    . HOH P 8 .   ? -13.75700 11.05400  29.73400 1.000 54.21459 ? 434 HOH A O    1 
HETATM 4411 O  O    . HOH P 8 .   ? 13.26000  -18.23900 11.34900 1.000 26.56274 ? 435 HOH A O    1 
HETATM 4412 O  O    . HOH P 8 .   ? -14.66400 -2.85400  10.64900 1.000 29.21209 ? 436 HOH A O    1 
HETATM 4413 O  O    . HOH P 8 .   ? -18.45900 -8.52400  34.43200 1.000 30.05982 ? 437 HOH A O    1 
HETATM 4414 O  O    . HOH P 8 .   ? -9.49900  -3.98000  40.48300 1.000 33.90864 ? 438 HOH A O    1 
HETATM 4415 O  O    . HOH P 8 .   ? -8.56400  -22.05000 34.89000 1.000 19.74567 ? 439 HOH A O    1 
HETATM 4416 O  O    . HOH P 8 .   ? 11.40900  -9.80300  0.97900  1.000 28.22824 ? 440 HOH A O    1 
HETATM 4417 O  O    . HOH P 8 .   ? -6.58900  -7.33200  7.53700  1.000 32.42597 ? 441 HOH A O    1 
HETATM 4418 O  O    . HOH P 8 .   ? 6.10700   -14.68400 32.54000 1.000 51.32561 ? 442 HOH A O    1 
HETATM 4419 O  O    . HOH P 8 .   ? -4.67800  -22.76000 31.19300 1.000 14.16353 ? 443 HOH A O    1 
HETATM 4420 O  O    . HOH P 8 .   ? -1.04300  -29.92900 4.94400  1.000 43.91850 ? 444 HOH A O    1 
HETATM 4421 O  O    . HOH P 8 .   ? -17.21000 -12.13000 32.84100 1.000 23.40534 ? 445 HOH A O    1 
HETATM 4422 O  O    . HOH P 8 .   ? 4.78700   2.63400   9.35500  1.000 20.55949 ? 446 HOH A O    1 
HETATM 4423 O  O    . HOH P 8 .   ? -24.23900 6.75600   29.95200 1.000 14.16326 ? 447 HOH A O    1 
HETATM 4424 O  O    . HOH P 8 .   ? -4.05200  -2.02900  1.49200  1.000 35.27020 ? 448 HOH A O    1 
HETATM 4425 O  O    . HOH P 8 .   ? -11.65400 -7.89300  13.82300 1.000 20.00387 ? 449 HOH A O    1 
HETATM 4426 O  O    . HOH P 8 .   ? -8.71700  6.53400   21.82800 1.000 15.37149 ? 450 HOH A O    1 
HETATM 4427 O  O    . HOH P 8 .   ? 4.56700   -2.59100  27.71300 1.000 15.01537 ? 451 HOH A O    1 
HETATM 4428 O  O    . HOH P 8 .   ? 10.21100  -13.01500 -5.16500 1.000 25.26511 ? 452 HOH A O    1 
HETATM 4429 O  O    . HOH P 8 .   ? 5.57900   -24.88700 20.45300 1.000 25.15382 ? 453 HOH A O    1 
HETATM 4430 O  O    . HOH P 8 .   ? 11.53700  -17.11600 1.18500  1.000 37.02792 ? 454 HOH A O    1 
HETATM 4431 O  O    . HOH P 8 .   ? -1.03100  -23.49800 24.80400 1.000 14.81671 ? 455 HOH A O    1 
HETATM 4432 O  O    . HOH P 8 .   ? 6.68500   -2.77900  15.42600 1.000 12.85195 ? 456 HOH A O    1 
HETATM 4433 O  O    . HOH P 8 .   ? -0.83400  5.78000   19.85300 1.000 11.10119 ? 457 HOH A O    1 
HETATM 4434 O  O    . HOH P 8 .   ? -9.74700  11.07400  14.38500 1.000 18.60011 ? 458 HOH A O    1 
HETATM 4435 O  O    . HOH P 8 .   ? -17.87000 -30.61600 13.13900 1.000 31.90292 ? 459 HOH A O    1 
HETATM 4436 O  O    . HOH P 8 .   ? 9.60500   -16.32600 34.09800 1.000 14.00111 ? 460 HOH A O    1 
HETATM 4437 O  O    . HOH P 8 .   ? 12.26500  -2.79900  4.24300  1.000 32.95334 ? 461 HOH A O    1 
HETATM 4438 O  O    . HOH P 8 .   ? 3.01400   6.11200   20.88100 1.000 16.93694 ? 462 HOH A O    1 
HETATM 4439 O  O    . HOH P 8 .   ? 0.18700   -30.45900 12.27900 1.000 38.44515 ? 463 HOH A O    1 
HETATM 4440 O  O    . HOH P 8 .   ? -9.67100  -11.70200 38.16800 1.000 28.02743 ? 464 HOH A O    1 
HETATM 4441 O  O    . HOH P 8 .   ? -24.06400 -1.27700  30.97600 1.000 20.03874 ? 465 HOH A O    1 
HETATM 4442 O  O    . HOH P 8 .   ? -23.10000 0.38900   17.93300 1.000 32.97264 ? 466 HOH A O    1 
HETATM 4443 O  O    . HOH P 8 .   ? 8.68300   -17.94600 19.90800 1.000 14.83488 ? 467 HOH A O    1 
HETATM 4444 O  O    . HOH P 8 .   ? -8.13900  -25.78700 3.53000  1.000 19.26308 ? 468 HOH A O    1 
HETATM 4445 O  O    . HOH P 8 .   ? -14.87000 -29.39600 15.04900 1.000 37.06730 ? 469 HOH A O    1 
HETATM 4446 O  O    . HOH P 8 .   ? -3.73200  -16.47000 35.32700 1.000 54.42998 ? 470 HOH A O    1 
HETATM 4447 O  O    . HOH P 8 .   ? -18.23500 -13.97100 31.01800 1.000 15.69346 ? 471 HOH A O    1 
HETATM 4448 O  O    . HOH P 8 .   ? -10.02100 -10.50300 6.07700  1.000 21.34779 ? 472 HOH A O    1 
HETATM 4449 O  O    . HOH P 8 .   ? 14.66200  -16.61400 2.37300  1.000 50.57296 ? 473 HOH A O    1 
HETATM 4450 O  O    . HOH P 8 .   ? -24.51900 -3.66500  29.78000 1.000 42.26250 ? 474 HOH A O    1 
HETATM 4451 O  O    . HOH P 8 .   ? 1.43600   -0.22700  4.26600  1.000 14.97627 ? 475 HOH A O    1 
HETATM 4452 O  O    . HOH P 8 .   ? -14.65700 -16.18900 2.76900  1.000 18.09524 ? 476 HOH A O    1 
HETATM 4453 O  O    . HOH P 8 .   ? 8.13500   -4.33300  13.59100 1.000 13.95027 ? 477 HOH A O    1 
HETATM 4454 O  O    . HOH P 8 .   ? 10.33400  -15.22800 23.77500 1.000 36.01334 ? 478 HOH A O    1 
HETATM 4455 O  O    . HOH P 8 .   ? 7.23100   -0.20900  14.48900 1.000 12.70363 ? 479 HOH A O    1 
HETATM 4456 O  O    . HOH P 8 .   ? -14.60600 -10.06100 6.52600  1.000 20.60543 ? 480 HOH A O    1 
HETATM 4457 O  O    . HOH P 8 .   ? 2.89000   -13.51200 -7.38300 1.000 48.15470 ? 481 HOH A O    1 
HETATM 4458 O  O    . HOH P 8 .   ? 6.70500   -29.18800 13.83200 1.000 48.04849 ? 482 HOH A O    1 
HETATM 4459 O  O    . HOH P 8 .   ? 7.34300   -5.20100  9.57400  1.000 15.71310 ? 483 HOH A O    1 
HETATM 4460 O  O    . HOH P 8 .   ? 4.23300   -1.62100  15.14400 1.000 12.23897 ? 484 HOH A O    1 
HETATM 4461 O  O    . HOH P 8 .   ? -8.95800  -17.57700 34.85600 1.000 26.86412 ? 485 HOH A O    1 
HETATM 4462 O  O    . HOH P 8 .   ? -3.41300  -10.94800 20.92600 0.651 13.41427 ? 486 HOH A O    1 
HETATM 4463 O  O    . HOH P 8 .   ? 2.39800   -7.29800  -2.29100 1.000 17.75391 ? 487 HOH A O    1 
HETATM 4464 O  O    . HOH P 8 .   ? -5.95700  -9.98400  7.60000  1.000 12.98692 ? 488 HOH A O    1 
HETATM 4465 O  O    . HOH P 8 .   ? -23.57800 5.48600   23.32000 1.000 24.89284 ? 489 HOH A O    1 
HETATM 4466 O  O    . HOH P 8 .   ? -0.26000  -19.67600 27.89000 1.000 14.99914 ? 490 HOH A O    1 
HETATM 4467 O  O    . HOH P 8 .   ? -11.29300 -27.27300 24.76300 1.000 32.30183 ? 491 HOH A O    1 
HETATM 4468 O  O    . HOH P 8 .   ? 4.82600   -5.15400  31.51000 1.000 14.37548 ? 492 HOH A O    1 
HETATM 4469 O  O    . HOH P 8 .   ? -16.27900 -5.01000  9.11000  1.000 33.75865 ? 493 HOH A O    1 
HETATM 4470 O  O    . HOH P 8 .   ? -10.13200 -26.79000 28.35800 1.000 30.32978 ? 494 HOH A O    1 
HETATM 4471 O  O    . HOH P 8 .   ? -7.42100  10.68700  20.21600 1.000 17.76591 ? 495 HOH A O    1 
HETATM 4472 O  O    . HOH P 8 .   ? -2.22100  -30.39900 8.40200  1.000 47.15217 ? 496 HOH A O    1 
HETATM 4473 O  O    . HOH P 8 .   ? -4.82700  3.36300   32.73800 1.000 27.41276 ? 497 HOH A O    1 
HETATM 4474 O  O    . HOH P 8 .   ? -4.97400  -5.39100  -1.29400 1.000 44.71991 ? 498 HOH A O    1 
HETATM 4475 O  O    . HOH P 8 .   ? -7.92400  -31.55800 13.59600 1.000 15.59269 ? 499 HOH A O    1 
HETATM 4476 O  O    . HOH P 8 .   ? 13.70900  -0.43200  9.29900  1.000 33.67969 ? 500 HOH A O    1 
HETATM 4477 O  O    . HOH P 8 .   ? -14.14200 -20.96100 5.28500  1.000 16.74362 ? 501 HOH A O    1 
HETATM 4478 O  O    . HOH P 8 .   ? -17.32800 -14.74500 8.19400  1.000 42.90703 ? 502 HOH A O    1 
HETATM 4479 O  O    . HOH P 8 .   ? -0.08700  -28.48900 1.46200  1.000 28.77086 ? 503 HOH A O    1 
HETATM 4480 O  O    . HOH P 8 .   ? 9.87200   -12.96500 0.04600  1.000 16.23503 ? 504 HOH A O    1 
HETATM 4481 O  O    . HOH P 8 .   ? 1.88500   -4.16200  16.14500 1.000 11.13699 ? 505 HOH A O    1 
HETATM 4482 O  O    . HOH P 8 .   ? 1.59300   -19.10200 25.91400 1.000 18.26155 ? 506 HOH A O    1 
HETATM 4483 O  O    . HOH P 8 .   ? -19.11300 -24.42500 31.59400 1.000 29.05122 ? 507 HOH A O    1 
HETATM 4484 O  O    . HOH P 8 .   ? -13.50800 5.48300   11.39300 1.000 31.26774 ? 508 HOH A O    1 
HETATM 4485 O  O    . HOH P 8 .   ? -3.27100  -13.96000 -5.02400 1.000 47.69955 ? 509 HOH A O    1 
HETATM 4486 O  O    . HOH P 8 .   ? -21.51800 8.67100   32.61900 1.000 48.10768 ? 510 HOH A O    1 
HETATM 4487 O  O    . HOH P 8 .   ? 4.09700   -16.77200 34.39100 1.000 19.78099 ? 511 HOH A O    1 
HETATM 4488 O  O    . HOH P 8 .   ? -12.60000 2.07100   32.18300 1.000 20.19197 ? 512 HOH A O    1 
HETATM 4489 O  O    . HOH P 8 .   ? -9.02400  12.68700  25.58500 1.000 27.81864 ? 513 HOH A O    1 
HETATM 4490 O  O    . HOH P 8 .   ? 11.58200  -6.93500  11.12800 1.000 27.47977 ? 514 HOH A O    1 
HETATM 4491 O  O    . HOH P 8 .   ? -13.86000 -23.53200 23.92200 1.000 40.11899 ? 515 HOH A O    1 
HETATM 4492 O  O    . HOH P 8 .   ? -20.29100 -13.45400 29.13300 1.000 16.09011 ? 516 HOH A O    1 
HETATM 4493 O  O    . HOH P 8 .   ? -24.51500 1.57500   24.76400 1.000 48.42357 ? 517 HOH A O    1 
HETATM 4494 O  O    . HOH P 8 .   ? -15.14500 -12.47700 9.49800  1.000 19.18124 ? 518 HOH A O    1 
HETATM 4495 O  O    . HOH P 8 .   ? -20.77700 -15.35100 17.55900 1.000 25.61612 ? 519 HOH A O    1 
HETATM 4496 O  O    . HOH P 8 .   ? 5.88200   -7.94700  -0.84300 1.000 18.84166 ? 520 HOH A O    1 
HETATM 4497 O  O    . HOH P 8 .   ? -21.26300 -8.89200  23.70800 1.000 30.61796 ? 521 HOH A O    1 
HETATM 4498 O  O    . HOH P 8 .   ? 3.70600   -10.81700 -4.86800 1.000 25.39279 ? 522 HOH A O    1 
HETATM 4499 O  O    . HOH P 8 .   ? -16.30200 -22.23400 28.16300 1.000 21.35872 ? 523 HOH A O    1 
HETATM 4500 O  O    . HOH P 8 .   ? 3.89600   2.72600   6.72600  1.000 37.15331 ? 524 HOH A O    1 
HETATM 4501 O  O    . HOH P 8 .   ? -9.45500  1.22700   35.45300 1.000 30.77285 ? 525 HOH A O    1 
HETATM 4502 O  O    . HOH P 8 .   ? -12.08700 -11.34200 16.98500 0.952 11.50875 ? 526 HOH A O    1 
HETATM 4503 O  O    . HOH P 8 .   ? -18.26800 -18.22600 13.26100 1.000 31.37041 ? 527 HOH A O    1 
HETATM 4504 O  O    A HOH P 8 .   ? -1.58700  -18.12800 35.46500 0.562 10.79884 ? 528 HOH A O    1 
HETATM 4505 O  O    B HOH P 8 .   ? -1.68300  -18.41900 34.42200 0.438 19.82640 ? 528 HOH A O    1 
HETATM 4506 O  O    . HOH P 8 .   ? -9.10600  -29.46300 21.33500 1.000 28.21229 ? 529 HOH A O    1 
HETATM 4507 O  O    . HOH P 8 .   ? -9.64500  -19.97200 28.53100 1.000 12.46410 ? 530 HOH A O    1 
HETATM 4508 O  O    . HOH P 8 .   ? 14.23900  -0.77700  13.14500 1.000 32.73859 ? 531 HOH A O    1 
HETATM 4509 O  O    . HOH P 8 .   ? -10.63400 -0.61800  37.38100 1.000 31.99099 ? 532 HOH A O    1 
HETATM 4510 O  O    . HOH P 8 .   ? 11.23600  -29.36500 2.43200  1.000 50.65928 ? 533 HOH A O    1 
HETATM 4511 O  O    . HOH P 8 .   ? -19.07900 6.88500   32.80800 1.000 51.43967 ? 534 HOH A O    1 
HETATM 4512 O  O    . HOH P 8 .   ? 11.57700  -8.03200  22.77500 1.000 31.23672 ? 535 HOH A O    1 
HETATM 4513 O  O    . HOH P 8 .   ? -2.23600  -7.25000  34.07600 1.000 17.87853 ? 536 HOH A O    1 
HETATM 4514 O  O    . HOH P 8 .   ? -11.86200 15.91900  25.86000 1.000 24.96381 ? 537 HOH A O    1 
HETATM 4515 O  O    . HOH P 8 .   ? -8.21800  -19.22100 -1.16600 1.000 42.68082 ? 538 HOH A O    1 
HETATM 4516 O  O    . HOH P 8 .   ? -16.82100 15.09000  22.80100 1.000 31.69432 ? 539 HOH A O    1 
HETATM 4517 O  O    . HOH P 8 .   ? -3.91800  -31.93200 21.56200 1.000 22.29572 ? 540 HOH A O    1 
HETATM 4518 O  O    . HOH P 8 .   ? -16.02400 -16.72700 5.11800  1.000 20.57555 ? 541 HOH A O    1 
HETATM 4519 O  O    . HOH P 8 .   ? 10.60800  -8.25600  7.36300  1.000 23.74291 ? 542 HOH A O    1 
HETATM 4520 O  O    . HOH P 8 .   ? 13.81400  -13.16300 8.63200  1.000 23.25153 ? 543 HOH A O    1 
HETATM 4521 O  O    . HOH P 8 .   ? 3.46200   -33.39100 20.62000 1.000 56.95082 ? 544 HOH A O    1 
HETATM 4522 O  O    . HOH P 8 .   ? 11.07200  -21.67500 9.89900  1.000 24.86636 ? 545 HOH A O    1 
HETATM 4523 O  O    . HOH P 8 .   ? -21.34600 -9.71600  26.60000 1.000 50.87386 ? 546 HOH A O    1 
HETATM 4524 O  O    . HOH P 8 .   ? 10.21800  -11.83100 28.32400 1.000 41.02898 ? 547 HOH A O    1 
HETATM 4525 O  O    . HOH P 8 .   ? 10.63000  -14.57500 19.51100 1.000 44.08056 ? 548 HOH A O    1 
HETATM 4526 O  O    . HOH P 8 .   ? 12.09100  0.21100   19.19800 1.000 24.96344 ? 549 HOH A O    1 
HETATM 4527 O  O    . HOH P 8 .   ? -17.18600 -19.44200 10.93600 1.000 25.53252 ? 550 HOH A O    1 
HETATM 4528 O  O    . HOH P 8 .   ? 12.57000  -20.41000 3.42000  1.000 46.34450 ? 551 HOH A O    1 
HETATM 4529 O  O    . HOH P 8 .   ? -18.32300 -34.94700 15.22100 1.000 29.14408 ? 552 HOH A O    1 
HETATM 4530 O  O    . HOH P 8 .   ? 2.85700   -10.97900 35.23500 1.000 14.47488 ? 553 HOH A O    1 
HETATM 4531 O  O    . HOH P 8 .   ? 2.32100   -35.40500 17.49800 1.000 39.03984 ? 554 HOH A O    1 
HETATM 4532 O  O    . HOH P 8 .   ? -11.61200 2.58900   29.62200 1.000 18.40520 ? 555 HOH A O    1 
HETATM 4533 O  O    . HOH P 8 .   ? -5.64600  -7.96700  0.80400  1.000 18.01971 ? 556 HOH A O    1 
HETATM 4534 O  O    . HOH P 8 .   ? -1.19500  -15.75300 -2.26800 1.000 26.73079 ? 557 HOH A O    1 
HETATM 4535 O  O    . HOH P 8 .   ? -6.22700  -26.90700 29.04200 1.000 15.09346 ? 558 HOH A O    1 
HETATM 4536 O  O    . HOH P 8 .   ? 13.18700  -11.70300 11.96800 1.000 31.09284 ? 559 HOH A O    1 
HETATM 4537 O  O    . HOH P 8 .   ? -20.36000 -3.11100  20.28800 1.000 25.33847 ? 560 HOH A O    1 
HETATM 4538 O  O    . HOH P 8 .   ? 3.06900   -22.62300 -2.49300 1.000 23.31927 ? 561 HOH A O    1 
HETATM 4539 O  O    . HOH P 8 .   ? 9.59900   -5.96300  6.28900  1.000 24.43909 ? 562 HOH A O    1 
HETATM 4540 O  O    . HOH P 8 .   ? -17.35100 -27.55700 12.69600 1.000 26.73375 ? 563 HOH A O    1 
HETATM 4541 O  O    A HOH P 8 .   ? 7.49800   -19.37500 -5.54000 0.569 27.18690 ? 564 HOH A O    1 
HETATM 4542 O  O    A HOH P 8 .   ? -12.88800 -32.15000 7.91900  0.538 33.20155 ? 565 HOH A O    1 
HETATM 4543 O  O    . HOH P 8 .   ? 1.97600   -3.19700  -2.47800 1.000 21.77535 ? 566 HOH A O    1 
HETATM 4544 O  O    . HOH P 8 .   ? -10.48500 9.50100   28.00600 1.000 29.24819 ? 567 HOH A O    1 
HETATM 4545 O  O    . HOH P 8 .   ? 2.24500   -13.70100 -4.39100 1.000 36.03171 ? 568 HOH A O    1 
HETATM 4546 O  O    . HOH P 8 .   ? -20.63100 2.35900   34.99800 1.000 25.80908 ? 569 HOH A O    1 
HETATM 4547 O  O    . HOH P 8 .   ? 7.37400   3.71200   21.97500 1.000 20.70478 ? 570 HOH A O    1 
HETATM 4548 O  O    . HOH P 8 .   ? -21.20300 -7.08900  33.70100 1.000 41.95684 ? 571 HOH A O    1 
HETATM 4549 O  O    . HOH P 8 .   ? 7.14600   -6.57500  12.12000 1.000 15.23917 ? 572 HOH A O    1 
HETATM 4550 O  O    . HOH P 8 .   ? 9.14700   -8.08900  4.64400  1.000 17.84986 ? 573 HOH A O    1 
HETATM 4551 O  O    . HOH P 8 .   ? -14.67400 -21.60400 35.29900 1.000 35.14828 ? 574 HOH A O    1 
HETATM 4552 O  O    . HOH P 8 .   ? 9.63400   -10.73100 25.24200 1.000 33.96686 ? 575 HOH A O    1 
HETATM 4553 O  O    . HOH P 8 .   ? -5.24400  -16.81600 -1.84800 1.000 18.90423 ? 576 HOH A O    1 
HETATM 4554 O  O    . HOH P 8 .   ? 5.87800   2.75500   23.97800 1.000 21.61611 ? 577 HOH A O    1 
HETATM 4555 O  O    . HOH P 8 .   ? 9.72600   -21.96600 12.67300 1.000 15.62916 ? 578 HOH A O    1 
HETATM 4556 O  O    . HOH P 8 .   ? 10.29800  -24.08100 9.36000  1.000 60.44548 ? 579 HOH A O    1 
HETATM 4557 O  O    . HOH P 8 .   ? 6.89100   -27.52500 11.44100 1.000 23.03591 ? 580 HOH A O    1 
HETATM 4558 O  O    . HOH P 8 .   ? -14.72100 -15.19600 12.57800 1.000 41.21088 ? 581 HOH A O    1 
HETATM 4559 O  O    . HOH P 8 .   ? 4.50800   -32.02700 4.32600  1.000 37.12888 ? 582 HOH A O    1 
HETATM 4560 O  O    . HOH P 8 .   ? -9.61100  -7.16500  7.32300  1.000 38.69319 ? 583 HOH A O    1 
HETATM 4561 O  O    . HOH P 8 .   ? 3.22700   -8.99000  10.83800 1.000 41.68108 ? 584 HOH A O    1 
HETATM 4562 O  O    . HOH P 8 .   ? 12.68300  -11.84900 14.87600 1.000 22.03841 ? 585 HOH A O    1 
HETATM 4563 O  O    . HOH P 8 .   ? -20.86800 -24.80100 9.24600  1.000 46.91701 ? 586 HOH A O    1 
HETATM 4564 O  O    . HOH P 8 .   ? -1.52500  -3.32100  5.40800  1.000 31.37718 ? 587 HOH A O    1 
HETATM 4565 O  O    . HOH P 8 .   ? -15.05100 -17.44000 36.18100 1.000 43.72071 ? 588 HOH A O    1 
HETATM 4566 O  O    . HOH P 8 .   ? -8.04400  -33.95200 12.35500 1.000 24.04399 ? 589 HOH A O    1 
HETATM 4567 O  O    . HOH P 8 .   ? 2.71600   2.97600   26.61700 1.000 18.78476 ? 590 HOH A O    1 
HETATM 4568 O  O    . HOH P 8 .   ? -21.78600 -8.77600  19.38600 1.000 49.04402 ? 591 HOH A O    1 
HETATM 4569 O  O    . HOH P 8 .   ? 9.75800   -8.26400  25.75700 1.000 37.01170 ? 592 HOH A O    1 
HETATM 4570 O  O    . HOH P 8 .   ? 4.61800   -31.49900 15.68100 1.000 27.36990 ? 593 HOH A O    1 
HETATM 4571 O  O    . HOH P 8 .   ? 13.37900  -3.61500  23.09300 1.000 36.42740 ? 594 HOH A O    1 
HETATM 4572 O  O    . HOH P 8 .   ? 11.72200  -19.10800 13.61300 1.000 19.27859 ? 595 HOH A O    1 
HETATM 4573 O  O    . HOH P 8 .   ? -25.51100 -6.18800  38.22600 1.000 58.21367 ? 596 HOH A O    1 
HETATM 4574 O  O    . HOH P 8 .   ? 4.51800   -3.70400  -2.32800 1.000 34.12050 ? 597 HOH A O    1 
HETATM 4575 O  O    . HOH P 8 .   ? -18.79400 -19.84700 22.88100 1.000 33.85190 ? 598 HOH A O    1 
HETATM 4576 O  O    B HOH P 8 .   ? -3.18000  -5.21700  5.49200  0.706 26.78692 ? 599 HOH A O    1 
HETATM 4577 O  O    . HOH P 8 .   ? -5.86600  4.50400   25.87900 1.000 19.19575 ? 600 HOH A O    1 
HETATM 4578 O  O    . HOH P 8 .   ? -21.87300 -12.03200 23.05500 1.000 32.88220 ? 601 HOH A O    1 
HETATM 4579 O  O    . HOH P 8 .   ? 10.25800  -24.24400 11.03300 1.000 37.48573 ? 602 HOH A O    1 
HETATM 4580 O  O    . HOH P 8 .   ? -17.35600 -26.82700 2.68800  1.000 17.03093 ? 603 HOH A O    1 
HETATM 4581 O  O    . HOH P 8 .   ? -13.45600 -27.51900 0.02900  1.000 44.34037 ? 604 HOH A O    1 
HETATM 4582 O  O    . HOH P 8 .   ? 9.60600   -6.79100  9.44800  1.000 18.55043 ? 605 HOH A O    1 
HETATM 4583 O  O    . HOH P 8 .   ? -13.82100 -27.18600 21.20200 1.000 27.81826 ? 606 HOH A O    1 
HETATM 4584 O  O    . HOH P 8 .   ? -21.32800 -9.88300  14.80600 1.000 46.38722 ? 607 HOH A O    1 
HETATM 4585 O  O    . HOH P 8 .   ? -0.86900  1.51400   1.46000  1.000 44.52997 ? 608 HOH A O    1 
HETATM 4586 O  O    . HOH P 8 .   ? 6.47500   -28.96700 9.19400  1.000 38.18528 ? 609 HOH A O    1 
HETATM 4587 O  O    . HOH P 8 .   ? -1.71300  -31.13100 11.09300 1.000 26.53345 ? 610 HOH A O    1 
HETATM 4588 O  O    . HOH P 8 .   ? -2.01400  -1.25200  5.38000  1.000 61.36621 ? 611 HOH A O    1 
HETATM 4589 O  O    . HOH P 8 .   ? -5.37000  -34.57900 11.99200 1.000 25.49733 ? 612 HOH A O    1 
HETATM 4590 O  O    . HOH P 8 .   ? -15.44700 -15.96800 38.15000 1.000 54.06074 ? 613 HOH A O    1 
HETATM 4591 O  O    . HOH P 8 .   ? -13.74000 15.79300  23.33500 1.000 21.44158 ? 614 HOH A O    1 
HETATM 4592 O  O    . HOH P 8 .   ? 3.62000   -29.73100 19.60400 1.000 42.43728 ? 615 HOH A O    1 
HETATM 4593 O  O    B HOH P 8 .   ? 5.22100   5.76100   17.64600 0.547 19.45652 ? 616 HOH A O    1 
HETATM 4594 O  O    . HOH P 8 .   ? 0.19400   3.56600   12.56100 1.000 37.42759 ? 617 HOH A O    1 
HETATM 4595 O  O    . HOH P 8 .   ? -21.22200 -11.45600 19.68800 1.000 29.92450 ? 618 HOH A O    1 
HETATM 4596 O  O    . HOH P 8 .   ? -17.74800 -19.49500 34.70900 1.000 46.01281 ? 619 HOH A O    1 
HETATM 4597 O  O    . HOH P 8 .   ? -12.99500 -1.28700  37.75100 1.000 40.48914 ? 620 HOH A O    1 
HETATM 4598 O  O    . HOH P 8 .   ? 2.38600   -29.34800 20.94100 1.000 15.28921 ? 621 HOH A O    1 
HETATM 4599 O  O    . HOH P 8 .   ? -19.16200 14.03200  26.23500 1.000 55.36199 ? 622 HOH A O    1 
HETATM 4600 O  O    . HOH P 8 .   ? 2.58700   -27.98400 21.84200 1.000 35.08328 ? 623 HOH A O    1 
HETATM 4601 O  O    . HOH P 8 .   ? 4.16200   6.89200   15.16200 1.000 33.95427 ? 624 HOH A O    1 
HETATM 4602 O  O    . HOH P 8 .   ? 1.08100   -16.19200 -4.25200 1.000 40.88123 ? 625 HOH A O    1 
HETATM 4603 O  O    . HOH P 8 .   ? 5.71100   -7.73500  31.73900 1.000 25.46614 ? 626 HOH A O    1 
HETATM 4604 O  O    . HOH P 8 .   ? -2.16100  2.99800   12.15800 1.000 33.63451 ? 627 HOH A O    1 
HETATM 4605 O  O    . HOH P 8 .   ? 11.87100  2.00000   14.94700 1.000 40.38056 ? 628 HOH A O    1 
HETATM 4606 O  O    . HOH P 8 .   ? -9.48300  -14.92700 38.71500 1.000 39.96332 ? 629 HOH A O    1 
HETATM 4607 O  O    . HOH P 8 .   ? 7.04100   -27.89900 20.80400 1.000 47.99666 ? 630 HOH A O    1 
HETATM 4608 O  O    . HOH P 8 .   ? -19.24900 -22.09000 8.58200  1.000 50.30398 ? 631 HOH A O    1 
HETATM 4609 O  O    . HOH P 8 .   ? -2.59300  -22.19200 -1.29800 1.000 34.81181 ? 632 HOH A O    1 
HETATM 4610 O  O    . HOH P 8 .   ? -22.13600 10.02800  17.68800 1.000 50.40392 ? 633 HOH A O    1 
HETATM 4611 O  O    . HOH P 8 .   ? -7.39300  -29.38800 23.42300 1.000 27.34975 ? 634 HOH A O    1 
HETATM 4612 O  O    . HOH P 8 .   ? 1.35500   -1.37900  -4.43800 1.000 37.76214 ? 635 HOH A O    1 
HETATM 4613 O  O    . HOH P 8 .   ? -4.20000  -0.31000  8.78600  1.000 41.68580 ? 636 HOH A O    1 
HETATM 4614 O  O    . HOH P 8 .   ? 9.48600   -26.35500 11.31400 1.000 55.81965 ? 637 HOH A O    1 
HETATM 4615 O  O    B HOH P 8 .   ? -7.37400  -2.98100  2.73700  0.512 40.52399 ? 638 HOH A O    1 
HETATM 4616 O  O    . HOH P 8 .   ? -21.31500 -15.95500 14.98800 1.000 47.62573 ? 639 HOH A O    1 
HETATM 4617 O  O    . HOH P 8 .   ? -19.20200 -10.81500 34.29300 1.000 48.03992 ? 640 HOH A O    1 
HETATM 4618 O  O    . HOH P 8 .   ? 11.73800  -14.04100 27.25100 1.000 51.95638 ? 641 HOH A O    1 
HETATM 4619 O  O    . HOH P 8 .   ? -11.65400 -26.87700 31.10400 1.000 61.09842 ? 642 HOH A O    1 
HETATM 4620 O  O    . HOH P 8 .   ? -0.95000  -22.44900 27.49600 1.000 12.59011 ? 643 HOH A O    1 
HETATM 4621 O  O    . HOH P 8 .   ? -16.56600 -19.44000 4.73100  1.000 20.04886 ? 644 HOH A O    1 
HETATM 4622 O  O    . HOH P 8 .   ? 1.31900   -28.40600 19.71700 1.000 49.94567 ? 645 HOH A O    1 
HETATM 4623 O  O    . HOH P 8 .   ? -21.26600 -36.59200 12.99900 1.000 57.79039 ? 646 HOH A O    1 
HETATM 4624 O  O    . HOH P 8 .   ? -22.27500 -8.56700  31.49000 1.000 53.71709 ? 647 HOH A O    1 
HETATM 4625 O  O    . HOH P 8 .   ? -2.32000  -0.56700  3.03600  1.000 57.60231 ? 648 HOH A O    1 
HETATM 4626 O  O    . HOH P 8 .   ? -16.69100 -16.15300 10.84200 1.000 44.55373 ? 649 HOH A O    1 
HETATM 4627 O  O    . HOH P 8 .   ? -0.34200  1.19800   5.73600  1.000 51.22102 ? 650 HOH A O    1 
HETATM 4628 O  O    . HOH P 8 .   ? 13.33000  -8.24500  21.17200 1.000 49.65650 ? 651 HOH A O    1 
HETATM 4629 O  O    . HOH P 8 .   ? 4.35300   -31.69100 23.49800 1.000 51.67838 ? 652 HOH A O    1 
HETATM 4630 O  O    . HOH P 8 .   ? -22.10900 -0.92200  20.49200 1.000 40.03010 ? 653 HOH A O    1 
HETATM 4631 O  O    A HOH P 8 .   ? 2.31800   -20.24300 -3.56400 0.720 39.60990 ? 654 HOH A O    1 
HETATM 4632 O  O    . HOH P 8 .   ? 2.44800   -36.32400 15.39700 1.000 45.45784 ? 655 HOH A O    1 
HETATM 4633 O  O    . HOH P 8 .   ? 13.17000  -9.04300  10.47800 1.000 51.38971 ? 656 HOH A O    1 
HETATM 4634 O  O    . HOH P 8 .   ? 4.13600   -7.85100  -4.49000 1.000 28.71125 ? 657 HOH A O    1 
HETATM 4635 O  O    . HOH P 8 .   ? 8.06500   -17.24200 -7.07000 1.000 29.83458 ? 658 HOH A O    1 
HETATM 4636 O  O    . HOH P 8 .   ? -17.26100 -12.26600 7.71900  1.000 43.72711 ? 659 HOH A O    1 
HETATM 4637 O  O    . HOH P 8 .   ? -16.12900 -22.00900 25.13300 1.000 38.96919 ? 660 HOH A O    1 
HETATM 4638 O  O    . HOH P 8 .   ? -1.56300  -5.50100  -3.39800 1.000 55.68236 ? 661 HOH A O    1 
HETATM 4639 O  O    . HOH P 8 .   ? -5.95000  -19.85100 -1.34400 1.000 36.82315 ? 662 HOH A O    1 
HETATM 4640 O  O    . HOH P 8 .   ? 7.70100   -19.16900 22.24400 1.000 29.86806 ? 663 HOH A O    1 
HETATM 4641 O  O    . HOH P 8 .   ? -21.88300 -6.66000  23.57300 1.000 45.69505 ? 664 HOH A O    1 
HETATM 4642 O  O    . HOH P 8 .   ? 0.80400   -14.42100 38.44000 1.000 17.23739 ? 665 HOH A O    1 
HETATM 4643 O  O    . HOH P 8 .   ? -6.63300  8.56100   21.96300 1.000 21.01507 ? 666 HOH A O    1 
HETATM 4644 O  O    B HOH P 8 .   ? -6.00600  -2.78300  4.42700  0.577 49.03678 ? 667 HOH A O    1 
HETATM 4645 O  O    B HOH P 8 .   ? 5.59300   6.05300   20.57100 0.394 20.95389 ? 668 HOH A O    1 
HETATM 4646 O  O    . HOH P 8 .   ? 11.13500  -9.46300  3.56100  1.000 19.14670 ? 669 HOH A O    1 
HETATM 4647 O  O    . HOH P 8 .   ? -19.81800 -3.61100  17.88800 1.000 25.83729 ? 670 HOH A O    1 
HETATM 4648 O  O    . HOH P 8 .   ? 5.38100   -27.12900 22.53600 1.000 36.47067 ? 671 HOH A O    1 
HETATM 4649 O  O    . HOH P 8 .   ? 5.43500   -20.37500 22.83700 1.000 24.50242 ? 672 HOH A O    1 
HETATM 4650 O  O    . HOH P 8 .   ? 14.50300  -12.01100 0.91400  1.000 31.74365 ? 673 HOH A O    1 
HETATM 4651 O  O    . HOH P 8 .   ? -20.17200 -26.76000 2.84700  1.000 35.68813 ? 674 HOH A O    1 
HETATM 4652 O  O    . HOH P 8 .   ? 10.57600  -16.32200 20.77400 1.000 42.49709 ? 675 HOH A O    1 
HETATM 4653 O  O    . HOH P 8 .   ? 12.25700  -14.20300 -0.33100 1.000 27.58876 ? 676 HOH A O    1 
HETATM 4654 O  O    . HOH P 8 .   ? -4.31500  -16.45800 -4.37100 1.000 42.33331 ? 677 HOH A O    1 
HETATM 4655 O  O    . HOH P 8 .   ? 2.80800   -13.48000 36.61600 1.000 31.30758 ? 678 HOH A O    1 
HETATM 4656 O  O    . HOH P 8 .   ? -10.64500 5.25200   29.96300 1.000 21.28054 ? 679 HOH A O    1 
HETATM 4657 O  O    . HOH P 8 .   ? -20.27700 -19.41300 14.42500 1.000 56.02869 ? 680 HOH A O    1 
HETATM 4658 O  O    . HOH P 8 .   ? 13.94100  -17.49000 14.66100 1.000 39.41338 ? 681 HOH A O    1 
HETATM 4659 O  O    . HOH P 8 .   ? 13.30800  -8.97100  7.08400  1.000 49.66776 ? 682 HOH A O    1 
HETATM 4660 O  O    . HOH P 8 .   ? -9.42200  4.72400   32.28500 1.000 31.07280 ? 683 HOH A O    1 
HETATM 4661 O  O    . HOH P 8 .   ? -6.93400  9.73700   24.37400 1.000 44.05415 ? 684 HOH A O    1 
HETATM 4662 O  O    . HOH P 8 .   ? 14.12900  -10.50500 8.38500  1.000 47.35172 ? 685 HOH A O    1 
HETATM 4663 O  O    . HOH P 8 .   ? 12.28500  -20.72400 7.10400  1.000 50.49602 ? 686 HOH A O    1 
HETATM 4664 O  O    . HOH P 8 .   ? 9.11000   -30.33700 8.81100  1.000 59.25826 ? 687 HOH A O    1 
HETATM 4665 O  O    . HOH P 8 .   ? 6.58200   -8.86700  33.99400 1.000 34.38403 ? 688 HOH A O    1 
HETATM 4666 O  O    . HOH P 8 .   ? -3.67800  -18.71200 33.69500 1.000 27.63270 ? 689 HOH A O    1 
HETATM 4667 O  O    . HOH P 8 .   ? -11.14700 -2.78900  42.27900 1.000 50.03672 ? 690 HOH A O    1 
HETATM 4668 O  O    . HOH P 8 .   ? 13.07700  -20.42400 9.54100  1.000 57.67600 ? 691 HOH A O    1 
HETATM 4669 O  O    . HOH P 8 .   ? -6.77700  5.70400   33.00800 1.000 17.67995 ? 692 HOH A O    1 
HETATM 4670 O  O    . HOH P 8 .   ? 7.05000   5.95900   13.97300 1.000 51.41343 ? 693 HOH A O    1 
HETATM 4671 O  O    . HOH P 8 .   ? -4.83600  -36.84000 13.49200 1.000 50.62514 ? 694 HOH A O    1 
HETATM 4672 O  O    . HOH P 8 .   ? -15.89400 -38.06500 9.31400  1.000 47.64066 ? 695 HOH A O    1 
HETATM 4673 O  O    . HOH P 8 .   ? -3.36800  4.56000   34.11400 1.000 48.53605 ? 696 HOH A O    1 
HETATM 4674 O  O    . HOH P 8 .   ? -1.61500  -24.49600 -2.12400 1.000 41.71901 ? 697 HOH A O    1 
HETATM 4675 O  O    . HOH P 8 .   ? 6.05100   -22.93000 22.80600 1.000 21.52775 ? 698 HOH A O    1 
HETATM 4676 O  O    . HOH P 8 .   ? -22.37500 -12.21500 30.31800 1.000 28.96689 ? 699 HOH A O    1 
HETATM 4677 O  O    . HOH P 8 .   ? -23.67000 -5.91800  25.71700 1.000 41.46316 ? 700 HOH A O    1 
HETATM 4678 O  O    . HOH P 8 .   ? 2.29600   3.79600   9.90700  1.000 38.47125 ? 701 HOH A O    1 
HETATM 4679 O  O    . HOH P 8 .   ? -23.62400 6.44700   32.71900 1.000 21.75111 ? 702 HOH A O    1 
HETATM 4680 O  O    . HOH P 8 .   ? -7.59100  -15.83900 -1.42700 1.000 29.14579 ? 703 HOH A O    1 
HETATM 4681 O  O    . HOH P 8 .   ? 4.00100   -15.65600 36.70900 1.000 21.07523 ? 704 HOH A O    1 
HETATM 4682 O  O    . HOH P 8 .   ? -18.41500 -21.73400 23.83400 1.000 63.14815 ? 705 HOH A O    1 
HETATM 4683 O  O    . HOH P 8 .   ? -11.54100 -19.58100 38.34700 1.000 43.10212 ? 706 HOH A O    1 
HETATM 4684 O  O    . HOH P 8 .   ? -7.41000  -7.60300  38.43400 1.000 37.71463 ? 707 HOH A O    1 
HETATM 4685 O  O    . HOH P 8 .   ? -21.93000 -25.41700 6.14100  1.000 54.12838 ? 708 HOH A O    1 
HETATM 4686 O  O    . HOH P 8 .   ? 14.46400  -18.09900 -7.96100 1.000 47.35364 ? 709 HOH A O    1 
HETATM 4687 O  O    . HOH P 8 .   ? 14.56900  1.96000   11.59800 1.000 50.61974 ? 710 HOH A O    1 
HETATM 4688 O  O    . HOH P 8 .   ? 12.15600  -5.28300  5.45300  1.000 23.62134 ? 711 HOH A O    1 
HETATM 4689 O  O    . HOH P 8 .   ? 0.55600   -5.57800  -3.56900 1.000 28.77247 ? 712 HOH A O    1 
HETATM 4690 O  O    . HOH P 8 .   ? 4.58400   -31.18900 9.08300  1.000 60.65401 ? 713 HOH A O    1 
HETATM 4691 O  O    . HOH P 8 .   ? -17.96300 -23.35800 26.04200 1.000 49.78413 ? 714 HOH A O    1 
HETATM 4692 O  O    . HOH P 8 .   ? 6.78800   4.40100   9.71800  1.000 48.57380 ? 715 HOH A O    1 
HETATM 4693 O  O    . HOH P 8 .   ? -11.17500 1.44500   37.48400 1.000 55.55734 ? 716 HOH A O    1 
HETATM 4694 O  O    . HOH P 8 .   ? -22.14200 -5.37500  20.99800 1.000 41.03234 ? 717 HOH A O    1 
HETATM 4695 O  O    . HOH P 8 .   ? 6.40000   -3.93300  33.38200 1.000 28.47957 ? 718 HOH A O    1 
HETATM 4696 O  O    . HOH P 8 .   ? 2.49900   -11.73900 -9.22000 1.000 39.63554 ? 719 HOH A O    1 
HETATM 4697 O  O    . HOH P 8 .   ? -22.17100 -2.58600  16.78800 1.000 46.03393 ? 720 HOH A O    1 
HETATM 4698 O  O    . HOH P 8 .   ? 13.90700  -9.42500  -0.05900 1.000 17.01680 ? 721 HOH A O    1 
HETATM 4699 O  O    . HOH P 8 .   ? 15.06800  -9.58600  4.12700  1.000 44.86171 ? 722 HOH A O    1 
HETATM 4700 O  O    . HOH P 8 .   ? 5.72400   -10.96200 35.03000 1.000 41.35980 ? 723 HOH A O    1 
HETATM 4701 O  O    . HOH P 8 .   ? 0.89200   -24.44100 -2.73500 1.000 37.51110 ? 724 HOH A O    1 
HETATM 4702 O  O    . HOH P 8 .   ? -11.67600 -28.24500 22.25900 1.000 22.34444 ? 725 HOH A O    1 
HETATM 4703 O  O    . HOH P 8 .   ? 12.99300  -7.35300  3.69200  1.000 25.87123 ? 726 HOH A O    1 
HETATM 4704 O  O    . HOH P 8 .   ? 2.80100   -31.93700 7.35000  1.000 62.99492 ? 727 HOH A O    1 
HETATM 4705 O  O    . HOH P 8 .   ? 6.01800   -31.22100 24.52100 1.000 47.50658 ? 728 HOH A O    1 
HETATM 4706 O  O    . HOH P 8 .   ? 6.66700   -31.65700 22.51500 1.000 43.47152 ? 729 HOH A O    1 
HETATM 4707 O  O    . HOH P 8 .   ? 3.44100   -2.69900  -6.10600 1.000 45.02561 ? 730 HOH A O    1 
HETATM 4708 O  O    . HOH P 8 .   ? -21.09100 -23.11800 23.37500 1.000 54.20769 ? 731 HOH A O    1 
HETATM 4709 O  O    . HOH P 8 .   ? 2.90300   6.50400   11.18600 1.000 44.09094 ? 732 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N  N   . ALA A 5   ? 0.65340 0.49887 0.38134 0.01224  0.07339  0.06255  28  ALA A N   
2    C  CA  . ALA A 5   ? 0.63947 0.47635 0.37875 0.02539  0.07384  0.03908  28  ALA A CA  
3    C  C   . ALA A 5   ? 0.60712 0.42565 0.37054 0.04620  0.08146  0.02390  28  ALA A C   
4    O  O   . ALA A 5   ? 0.61121 0.39455 0.37761 0.04370  0.08114  0.02935  28  ALA A O   
5    C  CB  . ALA A 5   ? 0.64992 0.49691 0.38265 0.01574  0.06790  0.03220  28  ALA A CB  
11   N  N   . ASP A 6   ? 0.56250 0.37236 0.35176 0.07673  0.09474  0.00356  29  ASP A N   
12   C  CA  . ASP A 6   ? 0.52242 0.34694 0.33117 0.07480  0.09749  -0.01181 29  ASP A CA  
13   C  C   . ASP A 6   ? 0.43466 0.25179 0.29419 0.05908  0.10702  -0.01123 29  ASP A C   
14   O  O   . ASP A 6   ? 0.43725 0.22018 0.28805 0.02183  0.12803  -0.01861 29  ASP A O   
15   C  CB  . ASP A 6   ? 0.58637 0.41738 0.35367 0.07895  0.09081  -0.01000 29  ASP A CB  
16   C  CG  . ASP A 6   ? 0.64908 0.48989 0.37387 0.07497  0.08897  -0.01200 29  ASP A CG  
17   O  OD1 . ASP A 6   ? 0.66930 0.50630 0.37404 0.06208  0.09237  -0.01367 29  ASP A OD1 
18   O  OD2 . ASP A 6   ? 0.68106 0.52487 0.38779 0.07425  0.07667  -0.00821 29  ASP A OD2 
23   N  N   A VAL A 7   ? 0.39541 0.24276 0.27958 0.05465  0.09644  -0.00277 30  VAL A N   
24   N  N   B VAL A 7   ? 0.39772 0.21394 0.27640 0.04427  0.09636  0.01283  30  VAL A N   
25   C  CA  A VAL A 7   ? 0.35446 0.23445 0.26301 0.05623  0.08431  -0.00659 30  VAL A CA  
26   C  CA  B VAL A 7   ? 0.35877 0.20415 0.25379 0.04544  0.08309  0.00485  30  VAL A CA  
27   C  C   A VAL A 7   ? 0.33579 0.24094 0.24994 0.04887  0.07225  -0.01050 30  VAL A C   
28   C  C   B VAL A 7   ? 0.32355 0.20867 0.23591 0.04344  0.07113  -0.00943 30  VAL A C   
29   O  O   A VAL A 7   ? 0.32767 0.23706 0.24522 0.04565  0.06798  -0.00974 30  VAL A O   
30   O  O   B VAL A 7   ? 0.29913 0.18674 0.22107 0.01682  0.05611  -0.00558 30  VAL A O   
31   C  CB  A VAL A 7   ? 0.33752 0.22806 0.26041 0.06510  0.08390  -0.00762 30  VAL A CB  
32   C  CB  B VAL A 7   ? 0.36965 0.22288 0.25188 0.04642  0.08149  0.00898  30  VAL A CB  
33   C  CG1 A VAL A 7   ? 0.32356 0.22477 0.26006 0.07164  0.08414  -0.00647 30  VAL A CG1 
34   C  CG1 B VAL A 7   ? 0.37071 0.24025 0.25177 0.05077  0.09236  0.01880  30  VAL A CG1 
35   C  CG2 A VAL A 7   ? 0.33251 0.23304 0.26011 0.06555  0.08878  -0.00955 30  VAL A CG2 
36   C  CG2 B VAL A 7   ? 0.37724 0.25129 0.25719 0.02883  0.08584  0.00035  30  VAL A CG2 
55   N  N   . GLN A 8   ? 0.33174 0.25104 0.24572 0.03532  0.06046  -0.00880 31  GLN A N   
56   C  CA  . GLN A 8   ? 0.32192 0.26084 0.25283 0.04651  0.04313  -0.00072 31  GLN A CA  
57   C  C   . GLN A 8   ? 0.30945 0.25367 0.25207 0.05143  0.03891  -0.00902 31  GLN A C   
58   O  O   . GLN A 8   ? 0.30822 0.24686 0.25737 0.01960  0.02981  0.00202  31  GLN A O   
59   C  CB  . GLN A 8   ? 0.34630 0.25807 0.26076 0.06347  0.04128  -0.00353 31  GLN A CB  
60   C  CG  . GLN A 8   ? 0.36796 0.24305 0.26732 0.06755  0.05410  -0.01752 31  GLN A CG  
61   C  CD  . GLN A 8   ? 0.38997 0.22681 0.27535 0.05235  0.04851  -0.01820 31  GLN A CD  
62   O  OE1 . GLN A 8   ? 0.41599 0.22498 0.28005 0.03519  0.04617  -0.00681 31  GLN A OE1 
63   N  NE2 . GLN A 8   ? 0.36883 0.24595 0.27878 0.06970  0.04709  -0.02364 31  GLN A NE2 
73   N  N   . GLN A 9   ? 0.32992 0.28112 0.25227 0.06677  0.06220  -0.02022 32  GLN A N   
74   C  CA  . GLN A 9   ? 0.35633 0.30873 0.25527 0.07491  0.08043  -0.02616 32  GLN A CA  
75   C  C   . GLN A 9   ? 0.31254 0.25390 0.23778 0.03895  0.07795  -0.02081 32  GLN A C   
76   O  O   . GLN A 9   ? 0.31478 0.22795 0.24430 0.02614  0.08443  -0.01779 32  GLN A O   
77   C  CB  . GLN A 9   ? 0.44981 0.39981 0.27499 0.08788  0.08547  -0.04060 32  GLN A CB  
78   C  CG  . GLN A 9   ? 0.55562 0.49129 0.29928 0.08832  0.08200  -0.04555 32  GLN A CG  
79   C  CD  . GLN A 9   ? 0.63824 0.57826 0.32181 0.08822  0.07376  -0.04393 32  GLN A CD  
80   O  OE1 . GLN A 9   ? 0.66992 0.60740 0.33853 0.09396  0.06530  -0.04637 32  GLN A OE1 
81   N  NE2 . GLN A 9   ? 0.66952 0.61284 0.32874 0.07941  0.06814  -0.03822 32  GLN A NE2 
90   N  N   . LYS A 10  ? 0.29230 0.22133 0.21345 0.03397  0.08568  -0.02199 33  LYS A N   
91   C  CA  . LYS A 10  ? 0.29166 0.19610 0.19614 0.00438  0.07123  -0.03118 33  LYS A CA  
92   C  C   . LYS A 10  ? 0.25598 0.19506 0.17382 -0.00585 0.05989  -0.03039 33  LYS A C   
93   O  O   . LYS A 10  ? 0.26519 0.18339 0.17001 0.01345  0.03636  -0.03386 33  LYS A O   
94   C  CB  . LYS A 10  ? 0.32295 0.20374 0.21215 0.00403  0.06241  -0.05516 33  LYS A CB  
95   C  CG  . LYS A 10  ? 0.39132 0.25338 0.23834 0.00418  0.06256  -0.07167 33  LYS A CG  
96   C  CD  . LYS A 10  ? 0.45045 0.34562 0.26387 0.01417  0.05697  -0.07863 33  LYS A CD  
97   C  CE  . LYS A 10  ? 0.50512 0.42655 0.28898 0.02908  0.05069  -0.07287 33  LYS A CE  
98   N  NZ  . LYS A 10  ? 0.54792 0.47839 0.30298 0.03320  0.04464  -0.07154 33  LYS A NZ  
112  N  N   . LEU A 11  ? 0.24313 0.19301 0.16479 0.00031  0.05377  -0.02265 34  LEU A N   
113  C  CA  . LEU A 11  ? 0.23074 0.18974 0.16590 -0.00799 0.03915  -0.01760 34  LEU A CA  
114  C  C   . LEU A 11  ? 0.24010 0.17059 0.17196 0.01090  0.03813  -0.02395 34  LEU A C   
115  O  O   . LEU A 11  ? 0.24595 0.18203 0.16661 0.00756  0.04862  -0.01084 34  LEU A O   
116  C  CB  . LEU A 11  ? 0.21683 0.18743 0.16305 -0.00499 0.03139  -0.02167 34  LEU A CB  
117  C  CG  . LEU A 11  ? 0.21438 0.20510 0.15658 -0.00713 0.02112  -0.02004 34  LEU A CG  
118  C  CD1 . LEU A 11  ? 0.22817 0.21267 0.15379 -0.02350 0.01224  -0.02124 34  LEU A CD1 
119  C  CD2 . LEU A 11  ? 0.20851 0.19546 0.15833 -0.01574 0.02063  -0.01871 34  LEU A CD2 
131  N  N   . ALA A 12  ? 0.23137 0.21064 0.19054 0.02126  0.03959  -0.01896 35  ALA A N   
132  C  CA  . ALA A 12  ? 0.23555 0.23106 0.20353 0.01376  0.05055  -0.00738 35  ALA A CA  
133  C  C   . ALA A 12  ? 0.24097 0.21574 0.19527 -0.00068 0.07280  -0.02227 35  ALA A C   
134  O  O   . ALA A 12  ? 0.23859 0.22173 0.19910 -0.01814 0.07295  -0.01282 35  ALA A O   
135  C  CB  . ALA A 12  ? 0.21697 0.24452 0.21670 0.01232  0.05575  -0.00500 35  ALA A CB  
141  N  N   . GLU A 13  ? 0.24326 0.21960 0.19291 -0.00690 0.07522  -0.02609 36  GLU A N   
142  C  CA  . GLU A 13  ? 0.27875 0.24242 0.19458 -0.00824 0.09565  -0.03082 36  GLU A CA  
143  C  C   . GLU A 13  ? 0.26695 0.22109 0.17536 -0.01936 0.08217  -0.02118 36  GLU A C   
144  O  O   . GLU A 13  ? 0.26987 0.21631 0.16850 -0.02070 0.08949  -0.01353 36  GLU A O   
145  C  CB  . GLU A 13  ? 0.35338 0.29078 0.22130 0.01749  0.09544  -0.05888 36  GLU A CB  
146  C  CG  . GLU A 13  ? 0.45780 0.37080 0.25586 -0.01152 0.09441  -0.06871 36  GLU A CG  
147  C  CD  . GLU A 13  ? 0.55032 0.43760 0.28521 -0.01933 0.10020  -0.07803 36  GLU A CD  
148  O  OE1 . GLU A 13  ? 0.59805 0.46331 0.29918 -0.04060 0.08474  -0.07879 36  GLU A OE1 
149  O  OE2 . GLU A 13  ? 0.58521 0.46549 0.30263 -0.01631 0.10272  -0.06688 36  GLU A OE2 
156  N  N   . LEU A 14  ? 0.24665 0.20748 0.16732 -0.02189 0.06270  -0.02470 37  LEU A N   
157  C  CA  . LEU A 14  ? 0.24510 0.19299 0.15648 -0.02813 0.05067  -0.01753 37  LEU A CA  
158  C  C   . LEU A 14  ? 0.24582 0.18416 0.15824 -0.04031 0.06512  -0.01138 37  LEU A C   
159  O  O   . LEU A 14  ? 0.24577 0.18794 0.15613 -0.04324 0.06137  -0.00942 37  LEU A O   
160  C  CB  . LEU A 14  ? 0.21718 0.18375 0.15623 -0.02932 0.05077  -0.01712 37  LEU A CB  
161  C  CG  . LEU A 14  ? 0.21365 0.16687 0.16345 -0.02975 0.04417  -0.01010 37  LEU A CG  
162  C  CD1 . LEU A 14  ? 0.23511 0.17400 0.16759 -0.01731 0.04014  0.00093  37  LEU A CD1 
163  C  CD2 . LEU A 14  ? 0.17766 0.19134 0.16496 -0.03158 0.05633  -0.01427 37  LEU A CD2 
175  N  N   . GLU A 15  ? 0.25317 0.17196 0.15452 -0.04090 0.06735  -0.01371 38  GLU A N   
176  C  CA  . GLU A 15  ? 0.22967 0.20176 0.15193 -0.04833 0.06021  -0.01091 38  GLU A CA  
177  C  C   . GLU A 15  ? 0.24075 0.22295 0.15566 -0.04557 0.05369  -0.01594 38  GLU A C   
178  O  O   . GLU A 15  ? 0.24606 0.20057 0.14791 -0.04363 0.04495  -0.00703 38  GLU A O   
179  C  CB  . GLU A 15  ? 0.21890 0.18256 0.15156 -0.02892 0.06405  -0.00698 38  GLU A CB  
180  C  CG  . GLU A 15  ? 0.20900 0.17937 0.15493 -0.01032 0.05893  -0.00381 38  GLU A CG  
181  C  CD  . GLU A 15  ? 0.21364 0.16437 0.14922 0.00545  0.05620  0.00491  38  GLU A CD  
182  O  OE1 . GLU A 15  ? 0.22552 0.18769 0.15662 0.02665  0.05893  -0.00286 38  GLU A OE1 
183  O  OE2 . GLU A 15  ? 0.21237 0.16573 0.13763 0.00609  0.04377  0.00586  38  GLU A OE2 
190  N  N   . ARG A 16  ? 0.25755 0.25361 0.17873 -0.04873 0.07775  -0.01974 39  ARG A N   
191  C  CA  . ARG A 16  ? 0.26967 0.26133 0.19126 -0.06782 0.09816  -0.03316 39  ARG A CA  
192  C  C   . ARG A 16  ? 0.27578 0.22935 0.18023 -0.06830 0.09452  -0.03655 39  ARG A C   
193  O  O   . ARG A 16  ? 0.27042 0.22363 0.20422 -0.06571 0.09559  -0.03149 39  ARG A O   
194  C  CB  . ARG A 16  ? 0.31120 0.30578 0.21160 -0.05071 0.12448  -0.05478 39  ARG A CB  
195  C  CG  . ARG A 16  ? 0.39088 0.36198 0.24373 -0.03767 0.13285  -0.06930 39  ARG A CG  
196  C  CD  . ARG A 16  ? 0.49022 0.42783 0.27249 -0.02906 0.13078  -0.07693 39  ARG A CD  
197  N  NE  . ARG A 16  ? 0.58059 0.48080 0.29866 -0.03466 0.12551  -0.06515 39  ARG A NE  
198  C  CZ  . ARG A 16  ? 0.64278 0.51684 0.31513 -0.04301 0.12511  -0.05355 39  ARG A CZ  
199  N  NH1 . ARG A 16  ? 0.65914 0.53633 0.32166 -0.02810 0.12655  -0.04872 39  ARG A NH1 
200  N  NH2 . ARG A 16  ? 0.67101 0.52926 0.32501 -0.05241 0.11700  -0.04836 39  ARG A NH2 
214  N  N   A GLN A 17  ? 0.28122 0.21882 0.16702 -0.07412 0.08789  -0.03268 40  GLN A N   
215  N  N   B GLN A 17  ? 0.27940 0.22940 0.16657 -0.06371 0.08278  -0.04848 40  GLN A N   
216  C  CA  A GLN A 17  ? 0.28939 0.22727 0.16261 -0.07974 0.08164  -0.00873 40  GLN A CA  
217  C  CA  B GLN A 17  ? 0.28841 0.24777 0.16099 -0.05569 0.06933  -0.04165 40  GLN A CA  
218  C  C   A GLN A 17  ? 0.27514 0.20872 0.14505 -0.05645 0.07173  -0.02352 40  GLN A C   
219  C  C   B GLN A 17  ? 0.26637 0.22555 0.14347 -0.05025 0.06135  -0.04379 40  GLN A C   
220  O  O   A GLN A 17  ? 0.28839 0.21101 0.14634 -0.05658 0.08185  -0.01702 40  GLN A O   
221  O  O   B GLN A 17  ? 0.26049 0.22927 0.14345 -0.07164 0.06092  -0.04557 40  GLN A O   
222  C  CB  A GLN A 17  ? 0.33113 0.26519 0.18498 -0.10551 0.05668  0.00828  40  GLN A CB  
223  C  CB  B GLN A 17  ? 0.33279 0.29064 0.17887 -0.05544 0.04050  -0.04877 40  GLN A CB  
224  C  CG  A GLN A 17  ? 0.36993 0.31838 0.20753 -0.14181 0.04385  0.01872  40  GLN A CG  
225  C  CG  B GLN A 17  ? 0.37862 0.34376 0.19717 -0.06727 0.02384  -0.06092 40  GLN A CG  
226  C  CD  A GLN A 17  ? 0.42662 0.38461 0.23441 -0.14653 0.03849  0.02570  40  GLN A CD  
227  C  CD  B GLN A 17  ? 0.41240 0.41024 0.21370 -0.06975 0.01524  -0.05954 40  GLN A CD  
228  O  OE1 A GLN A 17  ? 0.46425 0.42658 0.25224 -0.13820 0.02848  0.02249  40  GLN A OE1 
229  O  OE1 B GLN A 17  ? 0.42961 0.42510 0.21817 -0.06974 0.00904  -0.06395 40  GLN A OE1 
230  N  NE2 A GLN A 17  ? 0.44302 0.40847 0.24176 -0.14800 0.04234  0.01797  40  GLN A NE2 
231  N  NE2 B GLN A 17  ? 0.43028 0.43584 0.22226 -0.06960 0.01853  -0.06673 40  GLN A NE2 
248  N  N   . SER A 18  ? 0.26302 0.20655 0.13112 -0.04960 0.05456  -0.02861 41  SER A N   
249  C  CA  . SER A 18  ? 0.22975 0.19487 0.13034 -0.02602 0.03479  -0.01740 41  SER A CA  
250  C  C   . SER A 18  ? 0.19545 0.19018 0.12397 0.00298  0.02770  -0.00215 41  SER A C   
251  O  O   . SER A 18  ? 0.21057 0.20561 0.14468 0.01390  0.02127  0.00752  41  SER A O   
252  C  CB  . SER A 18  ? 0.24621 0.20176 0.13119 -0.05563 0.05140  -0.01042 41  SER A CB  
253  O  OG  . SER A 18  ? 0.26866 0.18709 0.12597 -0.03724 0.06891  -0.00464 41  SER A OG  
260  N  N   . GLY A 19  ? 0.19758 0.16907 0.11852 -0.00923 0.03464  0.00393  42  GLY A N   
261  C  CA  . GLY A 19  ? 0.21037 0.16313 0.11952 -0.01347 0.03210  0.01041  42  GLY A CA  
262  C  C   . GLY A 19  ? 0.20227 0.16786 0.12222 -0.02561 0.02811  0.01155  42  GLY A C   
263  O  O   . GLY A 19  ? 0.23104 0.18417 0.11901 -0.03248 0.02969  0.01595  42  GLY A O   
267  N  N   . GLY A 20  ? 0.19481 0.15538 0.11889 -0.00930 0.04119  0.00786  43  GLY A N   
268  C  CA  . GLY A 20  ? 0.19993 0.15203 0.11506 -0.01201 0.02992  0.00265  43  GLY A CA  
269  C  C   . GLY A 20  ? 0.18457 0.13565 0.11222 0.00208  0.04039  0.00927  43  GLY A C   
270  O  O   . GLY A 20  ? 0.20443 0.16447 0.11806 0.00613  0.03362  0.01271  43  GLY A O   
274  N  N   . ARG A 21  ? 0.17375 0.14519 0.10812 -0.00185 0.02979  0.01128  44  ARG A N   
275  C  CA  . ARG A 21  ? 0.17644 0.14360 0.11126 -0.00071 0.02987  0.00629  44  ARG A CA  
276  C  C   . ARG A 21  ? 0.17822 0.14323 0.10844 -0.00051 0.02590  0.00530  44  ARG A C   
277  O  O   . ARG A 21  ? 0.17199 0.14415 0.11132 0.00090  0.02038  0.00385  44  ARG A O   
278  C  CB  . ARG A 21  ? 0.19250 0.14779 0.12703 -0.01500 0.03290  0.00217  44  ARG A CB  
279  C  CG  . ARG A 21  ? 0.17626 0.16223 0.13202 -0.01601 0.03456  0.00074  44  ARG A CG  
280  C  CD  . ARG A 21  ? 0.18210 0.16122 0.13072 -0.00569 0.03318  -0.00287 44  ARG A CD  
281  N  NE  . ARG A 21  ? 0.19526 0.14648 0.12788 -0.02594 0.02125  0.00060  44  ARG A NE  
282  C  CZ  . ARG A 21  ? 0.16169 0.14761 0.12704 -0.02434 0.01857  0.00367  44  ARG A CZ  
283  N  NH1 . ARG A 21  ? 0.17671 0.16814 0.13736 -0.00630 0.02777  0.00462  44  ARG A NH1 
284  N  NH2 . ARG A 21  ? 0.17085 0.15840 0.12460 -0.00141 0.01226  -0.00715 44  ARG A NH2 
298  N  N   . LEU A 22  ? 0.18674 0.13262 0.11404 0.00051  0.02536  0.01225  45  LEU A N   
299  C  CA  . LEU A 22  ? 0.16894 0.12117 0.11498 0.00021  0.02300  0.00991  45  LEU A CA  
300  C  C   . LEU A 22  ? 0.16257 0.13603 0.12328 0.00891  0.01961  0.00183  45  LEU A C   
301  O  O   . LEU A 22  ? 0.17376 0.13910 0.12736 0.00499  0.02971  0.00450  45  LEU A O   
302  C  CB  . LEU A 22  ? 0.20883 0.13515 0.11577 0.01148  0.02607  -0.00213 45  LEU A CB  
303  C  CG  . LEU A 22  ? 0.21538 0.14477 0.12296 -0.01617 0.03112  -0.00191 45  LEU A CG  
304  C  CD1 . LEU A 22  ? 0.20290 0.15842 0.13067 -0.02891 0.02005  0.01642  45  LEU A CD1 
305  C  CD2 . LEU A 22  ? 0.23463 0.17792 0.13587 -0.03736 0.02679  -0.01636 45  LEU A CD2 
317  N  N   . GLY A 23  ? 0.15318 0.12878 0.11041 0.00770  0.01407  0.00373  46  GLY A N   
318  C  CA  . GLY A 23  ? 0.15179 0.12416 0.11162 -0.00708 0.01981  0.00864  46  GLY A CA  
319  C  C   . GLY A 23  ? 0.15619 0.12051 0.10501 -0.00772 0.01243  -0.00024 46  GLY A C   
320  O  O   . GLY A 23  ? 0.16510 0.11836 0.12463 0.00248  0.01593  0.01736  46  GLY A O   
324  N  N   . VAL A 24  ? 0.15577 0.11851 0.10673 -0.00319 0.01075  0.00008  47  VAL A N   
325  C  CA  . VAL A 24  ? 0.15156 0.11918 0.11694 -0.00299 0.00190  -0.00164 47  VAL A CA  
326  C  C   . VAL A 24  ? 0.14390 0.10574 0.11875 0.00307  0.01424  0.00312  47  VAL A C   
327  O  O   . VAL A 24  ? 0.16292 0.11674 0.12616 0.01209  0.01682  0.01055  47  VAL A O   
328  C  CB  . VAL A 24  ? 0.16465 0.14637 0.10772 -0.00111 0.01138  -0.00734 47  VAL A CB  
329  C  CG1 . VAL A 24  ? 0.18447 0.15103 0.11025 -0.00738 0.00804  -0.00962 47  VAL A CG1 
330  C  CG2 . VAL A 24  ? 0.17787 0.15168 0.10557 -0.00279 0.00763  -0.00161 47  VAL A CG2 
340  N  N   . ALA A 25  ? 0.15052 0.11132 0.12013 0.00872  0.02518  0.00969  48  ALA A N   
341  C  CA  . ALA A 25  ? 0.15130 0.10641 0.11022 0.01921  0.01116  0.00644  48  ALA A CA  
342  C  C   . ALA A 25  ? 0.14433 0.11019 0.10593 0.00018  0.00264  0.01060  48  ALA A C   
343  O  O   . ALA A 25  ? 0.15129 0.11402 0.11341 0.00623  0.00358  0.00900  48  ALA A O   
344  C  CB  . ALA A 25  ? 0.15415 0.12260 0.12235 0.01387  0.01577  0.00635  48  ALA A CB  
350  N  N   . LEU A 26  ? 0.17206 0.12115 0.12205 0.01146  0.00694  0.00041  49  LEU A N   
351  C  CA  . LEU A 26  ? 0.15958 0.10651 0.12893 0.00810  0.00842  0.00632  49  LEU A CA  
352  C  C   . LEU A 26  ? 0.15614 0.10364 0.13837 0.01491  0.01435  0.00858  49  LEU A C   
353  O  O   . LEU A 26  ? 0.18446 0.13317 0.15437 0.02558  0.03340  0.03286  49  LEU A O   
354  C  CB  . LEU A 26  ? 0.18066 0.12390 0.13306 -0.00221 0.00605  -0.00666 49  LEU A CB  
355  C  CG  . LEU A 26  ? 0.20804 0.14328 0.13825 0.00057  0.00429  -0.00234 49  LEU A CG  
356  C  CD1 . LEU A 26  ? 0.21741 0.17618 0.14569 -0.00701 -0.00049 -0.00090 49  LEU A CD1 
357  C  CD2 . LEU A 26  ? 0.24770 0.15699 0.15682 -0.00168 0.00962  -0.00598 49  LEU A CD2 
369  N  N   . ILE A 27  ? 0.15699 0.09768 0.12831 0.01274  0.01189  0.01354  50  ILE A N   
370  C  CA  . ILE A 27  ? 0.15818 0.10916 0.13043 0.01420  0.00179  0.01089  50  ILE A CA  
371  C  C   . ILE A 27  ? 0.16719 0.10096 0.12983 0.00482  -0.00352 0.01987  50  ILE A C   
372  O  O   . ILE A 27  ? 0.17343 0.10439 0.13504 -0.00472 -0.00382 0.00069  50  ILE A O   
373  C  CB  . ILE A 27  ? 0.18510 0.10750 0.12752 -0.00427 -0.00162 0.01607  50  ILE A CB  
374  C  CG1 . ILE A 27  ? 0.18046 0.12860 0.12616 -0.01817 0.00099  0.01151  50  ILE A CG1 
375  C  CG2 . ILE A 27  ? 0.20192 0.13404 0.14079 -0.01270 0.00286  0.01823  50  ILE A CG2 
376  C  CD1 . ILE A 27  ? 0.23099 0.18094 0.12335 -0.02986 -0.01113 0.02043  50  ILE A CD1 
388  N  N   . ASN A 28  ? 0.18945 0.10643 0.14044 -0.00378 0.00132  0.00617  51  ASN A N   
389  C  CA  . ASN A 28  ? 0.18539 0.11143 0.14192 -0.00871 0.00048  0.00377  51  ASN A CA  
390  C  C   . ASN A 28  ? 0.17458 0.10464 0.14305 -0.01718 0.00322  0.00909  51  ASN A C   
391  O  O   . ASN A 28  ? 0.19826 0.10566 0.16020 0.00558  0.00109  0.01369  51  ASN A O   
392  C  CB  . ASN A 28  ? 0.21722 0.11374 0.14282 0.00484  0.00396  0.00563  51  ASN A CB  
393  C  CG  . ASN A 28  ? 0.22947 0.12916 0.14271 -0.01817 0.00142  0.00176  51  ASN A CG  
394  O  OD1 . ASN A 28  ? 0.21814 0.13929 0.14565 -0.02552 -0.00207 -0.00245 51  ASN A OD1 
395  N  ND2 . ASN A 28  ? 0.26463 0.20196 0.14812 -0.04590 0.01301  -0.04322 51  ASN A ND2 
402  N  N   . THR A 29  ? 0.18228 0.11554 0.13172 -0.01581 -0.00617 0.00741  52  THR A N   
403  C  CA  . THR A 29  ? 0.19537 0.13746 0.13534 -0.02544 -0.01158 0.00876  52  THR A CA  
404  C  C   . THR A 29  ? 0.21008 0.13159 0.14375 -0.02880 -0.00829 0.01068  52  THR A C   
405  O  O   . THR A 29  ? 0.23680 0.13692 0.14931 -0.01028 -0.00444 0.02836  52  THR A O   
406  C  CB  . THR A 29  ? 0.21273 0.13232 0.12920 -0.00381 -0.00893 0.00912  52  THR A CB  
407  O  OG1 . THR A 29  ? 0.19305 0.13883 0.14020 -0.00996 -0.00670 0.02144  52  THR A OG1 
408  C  CG2 . THR A 29  ? 0.21419 0.13632 0.13764 0.00900  0.00285  -0.00782 52  THR A CG2 
416  N  N   . ALA A 30  ? 0.23475 0.11174 0.15138 -0.03392 -0.01072 0.01563  53  ALA A N   
417  C  CA  . ALA A 30  ? 0.23368 0.11655 0.18277 -0.03032 -0.00682 0.01209  53  ALA A CA  
418  C  C   . ALA A 30  ? 0.23072 0.12243 0.20168 -0.03598 0.00992  0.02670  53  ALA A C   
419  O  O   . ALA A 30  ? 0.25764 0.14258 0.22341 -0.02163 0.03042  0.02688  53  ALA A O   
420  C  CB  . ALA A 30  ? 0.24214 0.12018 0.18942 -0.04351 -0.00739 -0.01255 53  ALA A CB  
426  N  N   . ASP A 31  ? 0.22428 0.11564 0.20360 -0.01322 0.01461  0.01593  54  ASP A N   
427  C  CA  . ASP A 31  ? 0.23429 0.12519 0.20510 -0.01474 0.01771  0.02622  54  ASP A CA  
428  C  C   . ASP A 31  ? 0.21612 0.11981 0.18470 0.01766  0.01687  0.03236  54  ASP A C   
429  O  O   . ASP A 31  ? 0.23651 0.14172 0.17835 0.02101  0.02089  0.03185  54  ASP A O   
430  C  CB  . ASP A 31  ? 0.28112 0.14911 0.21556 -0.01107 0.01858  -0.01586 54  ASP A CB  
431  C  CG  . ASP A 31  ? 0.32138 0.17905 0.20914 -0.01466 0.03958  -0.03756 54  ASP A CG  
432  O  OD1 . ASP A 31  ? 0.28718 0.14595 0.19957 -0.00692 0.03511  -0.02058 54  ASP A OD1 
433  O  OD2 . ASP A 31  ? 0.40127 0.21386 0.22056 -0.01406 0.04903  -0.05616 54  ASP A OD2 
438  N  N   . ASN A 32  ? 0.19128 0.13066 0.17122 -0.00056 0.01585  0.01866  55  ASN A N   
439  C  CA  . ASN A 32  ? 0.19203 0.11491 0.17047 0.00880  0.01551  0.01563  55  ASN A CA  
440  C  C   . ASN A 32  ? 0.18659 0.13247 0.17622 -0.00945 0.01654  0.01665  55  ASN A C   
441  O  O   . ASN A 32  ? 0.20743 0.19505 0.18165 -0.01675 0.01725  0.00362  55  ASN A O   
442  C  CB  . ASN A 32  ? 0.20603 0.14008 0.17015 0.01307  0.00656  0.01735  55  ASN A CB  
443  C  CG  . ASN A 32  ? 0.22501 0.16011 0.16131 0.02566  0.02031  0.00491  55  ASN A CG  
444  O  OD1 . ASN A 32  ? 0.26398 0.17150 0.16624 0.02130  0.02848  -0.01401 55  ASN A OD1 
445  N  ND2 . ASN A 32  ? 0.25216 0.18448 0.15718 0.00950  0.01593  0.00412  55  ASN A ND2 
452  N  N   . SER A 33  ? 0.17619 0.15603 0.17842 0.01012  0.01924  0.04391  56  SER A N   
453  C  CA  . SER A 33  ? 0.19542 0.14154 0.18044 0.02303  0.02657  0.03550  56  SER A CA  
454  C  C   . SER A 33  ? 0.19265 0.12663 0.17435 0.03053  0.02788  0.03244  56  SER A C   
455  O  O   . SER A 33  ? 0.17552 0.13235 0.15945 0.02206  0.01338  0.02465  56  SER A O   
456  C  CB  . SER A 33  ? 0.24509 0.14673 0.19197 0.01996  0.04138  0.02518  56  SER A CB  
457  O  OG  . SER A 33  ? 0.25773 0.16066 0.18496 -0.00319 0.03639  0.01009  56  SER A OG  
463  N  N   A GLN A 34  ? 0.19565 0.13345 0.18101 0.03359  0.05150  0.03603  57  GLN A N   
464  N  N   B GLN A 34  ? 0.19524 0.13206 0.18743 0.03851  0.04397  0.04374  57  GLN A N   
465  C  CA  A GLN A 34  ? 0.19767 0.13175 0.17681 0.02619  0.04820  0.03162  57  GLN A CA  
466  C  CA  B GLN A 34  ? 0.20784 0.12925 0.19033 0.03956  0.03254  0.04891  57  GLN A CA  
467  C  C   A GLN A 34  ? 0.18181 0.11713 0.17676 0.02856  0.05189  0.00362  57  GLN A C   
468  C  C   B GLN A 34  ? 0.19284 0.11848 0.18449 0.02866  0.04317  0.02552  57  GLN A C   
469  O  O   A GLN A 34  ? 0.19433 0.13928 0.19013 0.03197  0.06053  -0.00051 57  GLN A O   
470  O  O   B GLN A 34  ? 0.21788 0.12197 0.19915 0.01544  0.05374  0.04442  57  GLN A O   
471  C  CB  A GLN A 34  ? 0.24842 0.16819 0.17257 0.00454  0.04728  0.03185  57  GLN A CB  
472  C  CB  B GLN A 34  ? 0.24515 0.14802 0.19805 0.05419  0.01828  0.05744  57  GLN A CB  
473  C  CG  A GLN A 34  ? 0.27786 0.20483 0.16949 -0.00005 0.03108  0.01702  57  GLN A CG  
474  C  CG  B GLN A 34  ? 0.25403 0.18526 0.20897 0.04655  -0.00402 0.04842  57  GLN A CG  
475  C  CD  A GLN A 34  ? 0.31112 0.23204 0.16956 0.00678  0.02827  0.00300  57  GLN A CD  
476  C  CD  B GLN A 34  ? 0.27793 0.21060 0.21878 0.05811  -0.01487 0.03796  57  GLN A CD  
477  O  OE1 A GLN A 34  ? 0.34048 0.25123 0.16912 0.01265  0.02773  0.01032  57  GLN A OE1 
478  O  OE1 B GLN A 34  ? 0.29380 0.19691 0.21937 0.04551  -0.01624 0.02764  57  GLN A OE1 
479  N  NE2 A GLN A 34  ? 0.34193 0.26905 0.17414 0.01194  0.02296  -0.00215 57  GLN A NE2 
480  N  NE2 B GLN A 34  ? 0.28005 0.23795 0.22970 0.06398  -0.02162 0.03528  57  GLN A NE2 
497  N  N   . ILE A 35  ? 0.16430 0.10966 0.15992 0.01300  0.02742  0.01666  58  ILE A N   
498  C  CA  . ILE A 35  ? 0.16942 0.12294 0.14821 0.00633  0.02467  0.00225  58  ILE A CA  
499  C  C   . ILE A 35  ? 0.16494 0.12858 0.14589 0.02094  0.01766  0.00588  58  ILE A C   
500  O  O   . ILE A 35  ? 0.16190 0.12373 0.15535 0.01201  0.02118  0.00274  58  ILE A O   
501  C  CB  . ILE A 35  ? 0.21683 0.15878 0.15124 -0.01330 0.00935  0.00216  58  ILE A CB  
502  C  CG1 . ILE A 35  ? 0.22356 0.19611 0.16950 -0.02418 -0.00390 -0.00618 58  ILE A CG1 
503  C  CG2 . ILE A 35  ? 0.25891 0.20322 0.14937 -0.01906 0.00689  0.02181  58  ILE A CG2 
504  C  CD1 . ILE A 35  ? 0.27135 0.21112 0.17924 -0.02104 -0.01432 0.01517  58  ILE A CD1 
516  N  N   . LEU A 36  ? 0.15756 0.11605 0.15587 0.01822  0.02246  0.00238  59  LEU A N   
517  C  CA  . LEU A 36  ? 0.17533 0.12271 0.15546 0.00888  0.02434  0.00054  59  LEU A CA  
518  C  C   . LEU A 36  ? 0.17727 0.12739 0.15032 0.00699  0.03382  -0.00264 59  LEU A C   
519  O  O   . LEU A 36  ? 0.20179 0.13242 0.18478 0.01852  0.05952  -0.00313 59  LEU A O   
520  C  CB  . LEU A 36  ? 0.17280 0.14094 0.16120 0.01245  0.01489  -0.00016 59  LEU A CB  
521  C  CG  . LEU A 36  ? 0.21378 0.16316 0.16677 0.00316  0.00630  0.01372  59  LEU A CG  
522  C  CD1 . LEU A 36  ? 0.23547 0.25791 0.18141 0.01183  -0.00669 0.02875  59  LEU A CD1 
523  C  CD2 . LEU A 36  ? 0.23736 0.16559 0.15711 0.00276  0.03468  0.00927  59  LEU A CD2 
535  N  N   . TYR A 37  ? 0.16523 0.12119 0.13142 0.00072  0.01580  0.00412  60  TYR A N   
536  C  CA  . TYR A 37  ? 0.15845 0.14199 0.13029 0.00469  0.02028  -0.00187 60  TYR A CA  
537  C  C   . TYR A 37  ? 0.16149 0.11937 0.12586 0.01520  0.01772  0.00629  60  TYR A C   
538  O  O   . TYR A 37  ? 0.14377 0.12721 0.14039 0.00319  0.02094  0.00645  60  TYR A O   
539  C  CB  . TYR A 37  ? 0.16075 0.15075 0.12912 0.00091  0.01259  0.00228  60  TYR A CB  
540  C  CG  . TYR A 37  ? 0.20612 0.15750 0.13073 0.00958  0.02589  -0.00772 60  TYR A CG  
541  C  CD1 . TYR A 37  ? 0.21859 0.14403 0.12861 -0.00407 0.01725  -0.00276 60  TYR A CD1 
542  C  CD2 . TYR A 37  ? 0.22892 0.16319 0.13877 0.01801  0.04960  -0.00847 60  TYR A CD2 
543  C  CE1 . TYR A 37  ? 0.21061 0.14543 0.14097 0.00834  0.03694  0.00030  60  TYR A CE1 
544  C  CE2 . TYR A 37  ? 0.24811 0.16461 0.14690 0.02891  0.05851  -0.00292 60  TYR A CE2 
545  C  CZ  . TYR A 37  ? 0.23037 0.15947 0.14751 0.01643  0.05321  0.00780  60  TYR A CZ  
546  O  OH  . TYR A 37  ? 0.25223 0.18469 0.16227 0.02243  0.07393  0.01535  60  TYR A OH  
556  N  N   . ARG A 38  ? 0.15136 0.14436 0.13917 0.00514  0.02033  0.00296  61  ARG A N   
557  C  CA  . ARG A 38  ? 0.15827 0.12889 0.13840 0.00960  0.01613  -0.00040 61  ARG A CA  
558  C  C   . ARG A 38  ? 0.16260 0.13108 0.14039 0.01811  0.01968  -0.00336 61  ARG A C   
559  O  O   . ARG A 38  ? 0.17402 0.14060 0.13807 0.00598  0.02530  0.00209  61  ARG A O   
560  C  CB  . ARG A 38  ? 0.15118 0.12724 0.14341 0.00511  0.01908  0.00607  61  ARG A CB  
561  C  CG  . ARG A 38  ? 0.15797 0.15392 0.14619 -0.00733 0.03086  0.01140  61  ARG A CG  
562  C  CD  . ARG A 38  ? 0.17135 0.14136 0.14656 -0.01096 0.03698  0.00631  61  ARG A CD  
563  N  NE  . ARG A 38  ? 0.18792 0.16955 0.14919 0.00637  0.03978  -0.00678 61  ARG A NE  
564  C  CZ  . ARG A 38  ? 0.19379 0.20728 0.15538 0.01049  0.04226  0.00374  61  ARG A CZ  
565  N  NH1 . ARG A 38  ? 0.19536 0.22286 0.16198 -0.00575 0.05050  0.00930  61  ARG A NH1 
566  N  NH2 . ARG A 38  ? 0.20529 0.27013 0.16234 0.00662  0.04965  -0.00456 61  ARG A NH2 
580  N  N   . ALA A 39  ? 0.18427 0.13032 0.13073 0.01729  0.02736  -0.00105 62  ALA A N   
581  C  CA  . ALA A 39  ? 0.18056 0.12508 0.13097 -0.00416 0.02273  -0.00931 62  ALA A CA  
582  C  C   . ALA A 39  ? 0.14574 0.12075 0.13913 0.00908  0.01773  0.00077  62  ALA A C   
583  O  O   . ALA A 39  ? 0.15974 0.12389 0.13527 0.00244  0.01974  -0.00052 62  ALA A O   
584  C  CB  . ALA A 39  ? 0.16655 0.14955 0.12611 -0.02156 0.02718  -0.00577 62  ALA A CB  
590  N  N   . ASP A 40  ? 0.16260 0.13232 0.14125 0.00093  0.01438  0.00109  63  ASP A N   
591  C  CA  . ASP A 40  ? 0.15658 0.14001 0.15609 0.00460  0.00547  0.00231  63  ASP A CA  
592  C  C   . ASP A 40  ? 0.17200 0.13971 0.15222 0.00682  0.00519  0.00181  63  ASP A C   
593  O  O   . ASP A 40  ? 0.21879 0.17030 0.16938 -0.02067 -0.00886 0.01297  63  ASP A O   
594  C  CB  . ASP A 40  ? 0.17640 0.16608 0.17876 0.03016  0.00792  0.01219  63  ASP A CB  
595  C  CG  . ASP A 40  ? 0.16743 0.15861 0.18825 0.02481  0.01923  0.02091  63  ASP A CG  
596  O  OD1 . ASP A 40  ? 0.19602 0.16025 0.18388 0.01241  0.02331  0.01846  63  ASP A OD1 
597  O  OD2 . ASP A 40  ? 0.21254 0.16718 0.20065 0.02941  0.02766  0.01930  63  ASP A OD2 
602  N  N   . GLU A 41  ? 0.17170 0.13160 0.13620 0.00089  0.00396  0.00212  64  GLU A N   
603  C  CA  . GLU A 41  ? 0.14269 0.14145 0.13393 -0.00224 0.01368  0.00471  64  GLU A CA  
604  C  C   . GLU A 41  ? 0.14139 0.15158 0.12919 0.00398  0.02596  0.01716  64  GLU A C   
605  O  O   . GLU A 41  ? 0.14838 0.14212 0.13778 -0.00442 0.02787  -0.00110 64  GLU A O   
606  C  CB  . GLU A 41  ? 0.15277 0.16615 0.13916 0.00385  0.01008  -0.00916 64  GLU A CB  
607  C  CG  . GLU A 41  ? 0.16170 0.17485 0.14721 0.01673  0.02035  0.00083  64  GLU A CG  
608  C  CD  . GLU A 41  ? 0.18252 0.16919 0.15726 0.01444  0.03349  0.00286  64  GLU A CD  
609  O  OE1 . GLU A 41  ? 0.20596 0.17859 0.16823 0.01411  0.04952  0.00637  64  GLU A OE1 
610  O  OE2 . GLU A 41  ? 0.19535 0.19092 0.16281 0.02183  0.04694  0.00022  64  GLU A OE2 
617  N  N   . ARG A 42  ? 0.15853 0.13957 0.13545 -0.00571 0.01943  0.00947  65  ARG A N   
618  C  CA  . ARG A 42  ? 0.15220 0.13818 0.12857 -0.00162 0.02793  -0.00109 65  ARG A CA  
619  C  C   . ARG A 42  ? 0.14549 0.11146 0.12380 -0.01373 0.01253  -0.00221 65  ARG A C   
620  O  O   . ARG A 42  ? 0.15628 0.14632 0.12957 -0.01888 0.02093  0.00239  65  ARG A O   
621  C  CB  . ARG A 42  ? 0.14475 0.14347 0.12786 -0.00429 0.00750  -0.00761 65  ARG A CB  
622  C  CG  . ARG A 42  ? 0.17199 0.18218 0.13032 -0.00130 -0.00448 -0.00422 65  ARG A CG  
623  C  CD  . ARG A 42  ? 0.17290 0.21593 0.13965 -0.01796 -0.01167 -0.00517 65  ARG A CD  
624  N  NE  . ARG A 42  ? 0.17869 0.23148 0.14791 0.00830  -0.00735 0.01213  65  ARG A NE  
625  C  CZ  . ARG A 42  ? 0.19338 0.19668 0.13573 0.00757  0.00687  0.01113  65  ARG A CZ  
626  N  NH1 . ARG A 42  ? 0.17852 0.17299 0.12932 0.01536  0.02896  0.00873  65  ARG A NH1 
627  N  NH2 . ARG A 42  ? 0.21547 0.22428 0.13964 0.01538  -0.00640 0.01037  65  ARG A NH2 
641  N  N   . PHE A 43  ? 0.13862 0.11852 0.11771 -0.01027 0.00240  -0.00347 66  PHE A N   
642  C  CA  . PHE A 43  ? 0.15686 0.12836 0.11415 -0.01061 0.00575  -0.00710 66  PHE A CA  
643  C  C   . PHE A 43  ? 0.15490 0.12658 0.10440 -0.02160 0.00691  0.01006  66  PHE A C   
644  O  O   . PHE A 43  ? 0.14812 0.12776 0.09985 -0.00819 0.01273  0.00380  66  PHE A O   
645  C  CB  . PHE A 43  ? 0.14461 0.14177 0.11621 -0.00789 0.01694  -0.01412 66  PHE A CB  
646  C  CG  . PHE A 43  ? 0.16372 0.12043 0.11769 -0.01805 0.02251  -0.01701 66  PHE A CG  
647  C  CD1 . PHE A 43  ? 0.15317 0.13767 0.11102 -0.02344 0.02513  -0.01115 66  PHE A CD1 
648  C  CD2 . PHE A 43  ? 0.16079 0.13278 0.12243 -0.00587 0.02240  -0.01249 66  PHE A CD2 
649  C  CE1 . PHE A 43  ? 0.15653 0.13157 0.12286 -0.01452 0.01836  0.00033  66  PHE A CE1 
650  C  CE2 . PHE A 43  ? 0.15460 0.14572 0.12265 -0.02789 0.01831  -0.00717 66  PHE A CE2 
651  C  CZ  . PHE A 43  ? 0.14919 0.12875 0.12996 -0.02516 0.02897  -0.00977 66  PHE A CZ  
661  N  N   . ALA A 44  ? 0.15495 0.13208 0.10104 -0.01531 0.01650  -0.00148 67  ALA A N   
662  C  CA  . ALA A 44  ? 0.14961 0.12069 0.10137 -0.01547 0.01197  0.00337  67  ALA A CA  
663  C  C   . ALA A 44  ? 0.15525 0.11245 0.10172 -0.01273 0.00036  0.00320  67  ALA A C   
664  O  O   . ALA A 44  ? 0.16667 0.15427 0.09727 -0.03461 0.00158  -0.01453 67  ALA A O   
665  C  CB  . ALA A 44  ? 0.15299 0.13116 0.11600 -0.01268 0.00209  0.01502  67  ALA A CB  
671  N  N   . MET A 45  ? 0.14399 0.11662 0.09759 -0.01281 0.00948  -0.00200 68  MET A N   
672  C  CA  . MET A 45  ? 0.14573 0.12013 0.09281 -0.01075 0.00554  -0.00155 68  MET A CA  
673  C  C   . MET A 45  ? 0.13198 0.11927 0.09527 -0.02134 0.00488  0.00016  68  MET A C   
674  O  O   . MET A 45  ? 0.13998 0.11104 0.10768 0.00132  0.00456  -0.00171 68  MET A O   
675  C  CB  . MET A 45  ? 0.14221 0.12916 0.10169 -0.01773 0.01056  -0.00080 68  MET A CB  
676  C  CG  . MET A 45  ? 0.16849 0.12684 0.09615 0.00040  0.00902  0.00033  68  MET A CG  
677  S  SD  . MET A 45  ? 0.15726 0.13722 0.10528 -0.00700 0.00536  0.00582  68  MET A SD  
678  C  CE  . MET A 45  ? 0.18190 0.12565 0.10698 -0.01346 0.01316  -0.00093 68  MET A CE  
688  N  N   . CYS A 46  ? 0.16010 0.12106 0.10236 -0.01515 0.00546  -0.00358 69  CYS A N   
689  C  CA  . CYS A 46  ? 0.14903 0.10452 0.10338 0.00078  0.00439  0.00568  69  CYS A CA  
690  C  C   . CYS A 46  ? 0.15607 0.09407 0.10668 0.00191  0.01173  -0.00248 69  CYS A C   
691  O  O   . CYS A 46  ? 0.16448 0.11747 0.09786 -0.01070 0.00768  -0.00288 69  CYS A O   
692  C  CB  . CYS A 46  ? 0.16691 0.11322 0.10793 -0.00598 0.00735  0.01880  69  CYS A CB  
693  S  SG  . CYS A 46  ? 0.17208 0.15166 0.11363 -0.00924 0.00913  0.01006  69  CYS A SG  
699  N  N   . SER A 47  ? 0.13250 0.10830 0.11649 -0.00234 0.00867  -0.00499 70  SER A N   
700  C  CA  . SER A 47  ? 0.14904 0.09999 0.12187 -0.00154 -0.00079 -0.00242 70  SER A CA  
701  C  C   . SER A 47  ? 0.14372 0.10072 0.11134 -0.00134 0.00149  0.00180  70  SER A C   
702  O  O   . SER A 47  ? 0.14490 0.12579 0.11084 -0.01079 0.00783  0.00545  70  SER A O   
703  C  CB  . SER A 47  ? 0.14828 0.10765 0.13192 0.01229  -0.00429 0.01067  70  SER A CB  
704  O  OG  . SER A 47  ? 0.18907 0.12666 0.12718 0.00525  -0.00934 0.00497  70  SER A OG  
709  N  N   . THR A 48  ? 0.15129 0.10341 0.11028 -0.00290 0.00389  0.00863  71  THR A N   
710  C  CA  . THR A 48  ? 0.15051 0.10556 0.10669 -0.00056 0.00062  -0.00409 71  THR A CA  
711  C  C   . THR A 48  ? 0.14159 0.10887 0.10811 0.00053  0.00487  0.00001  71  THR A C   
712  O  O   . THR A 48  ? 0.16716 0.11144 0.10889 -0.01632 0.00988  0.00598  71  THR A O   
713  C  CB  . THR A 48  ? 0.14341 0.10292 0.11191 -0.00993 0.00760  0.00031  71  THR A CB  
714  O  OG1 . THR A 48  ? 0.14502 0.11632 0.10527 -0.01820 0.01251  0.00313  71  THR A OG1 
715  C  CG2 . THR A 48  ? 0.13005 0.10423 0.11488 0.00539  0.01007  -0.00350 71  THR A CG2 
723  N  N   . SER A 49  ? 0.14741 0.11213 0.09833 -0.00906 0.00194  -0.00193 72  SER A N   
724  C  CA  . SER A 49  ? 0.14519 0.12825 0.10504 -0.01084 0.00570  -0.00359 72  SER A CA  
725  C  C   . SER A 49  ? 0.14803 0.10334 0.11047 -0.01303 0.00982  -0.00669 72  SER A C   
726  O  O   . SER A 49  ? 0.15455 0.11856 0.10397 -0.01619 0.01091  -0.00342 72  SER A O   
727  C  CB  . SER A 49  ? 0.15011 0.12341 0.10285 -0.00649 0.00094  -0.00894 72  SER A CB  
728  O  OG  . SER A 49  ? 0.16873 0.11587 0.10950 -0.00957 0.01132  -0.01620 72  SER A OG  
734  N  N   . LYS A 50  ? 0.12038 0.12747 0.11723 -0.00742 0.00552  0.00095  73  LYS A N   
735  C  CA  . LYS A 50  ? 0.12208 0.13021 0.12143 0.00815  0.00517  -0.00383 73  LYS A CA  
736  C  C   . LYS A 50  ? 0.13524 0.11214 0.11855 -0.00523 0.01773  -0.00954 73  LYS A C   
737  O  O   . LYS A 50  ? 0.14898 0.11604 0.12169 -0.00652 0.00954  -0.00314 73  LYS A O   
738  C  CB  . LYS A 50  ? 0.11472 0.11641 0.12770 0.00394  0.01180  -0.00905 73  LYS A CB  
739  C  CG  . LYS A 50  ? 0.15407 0.12596 0.12402 -0.00283 -0.00032 -0.00785 73  LYS A CG  
740  C  CD  . LYS A 50  ? 0.17091 0.12566 0.13273 0.00353  0.00057  -0.01010 73  LYS A CD  
741  C  CE  . LYS A 50  ? 0.21374 0.13519 0.12218 0.00943  -0.00693 -0.00656 73  LYS A CE  
742  N  NZ  . LYS A 50  ? 0.25829 0.15003 0.14295 0.01335  -0.03047 -0.00899 73  LYS A NZ  
756  N  N   . VAL A 51  ? 0.15140 0.10818 0.11098 -0.01157 0.01728  -0.01128 74  VAL A N   
757  C  CA  . VAL A 51  ? 0.14311 0.11727 0.12017 -0.01326 0.01314  -0.00217 74  VAL A CA  
758  C  C   . VAL A 51  ? 0.13361 0.11426 0.12265 -0.01818 0.01292  -0.00229 74  VAL A C   
759  O  O   . VAL A 51  ? 0.13177 0.12004 0.11702 -0.01508 0.01849  -0.00447 74  VAL A O   
760  C  CB  . VAL A 51  ? 0.15542 0.11952 0.11853 -0.01509 0.01358  -0.00240 74  VAL A CB  
761  C  CG1 . VAL A 51  ? 0.16972 0.12697 0.12088 -0.00366 0.00509  -0.00613 74  VAL A CG1 
762  C  CG2 . VAL A 51  ? 0.17205 0.13028 0.12431 -0.00548 0.00492  -0.00487 74  VAL A CG2 
772  N  N   A MET A 52  ? 0.13504 0.12331 0.11650 -0.00894 0.00732  -0.00413 75  MET A N   
773  N  N   B MET A 52  ? 0.15322 0.14239 0.10807 -0.01950 0.01673  -0.00313 75  MET A N   
774  C  CA  A MET A 52  ? 0.12807 0.12279 0.11751 -0.00819 -0.00027 -0.00683 75  MET A CA  
775  C  CA  B MET A 52  ? 0.16277 0.13376 0.11156 -0.03318 0.01405  0.00065  75  MET A CA  
776  C  C   A MET A 52  ? 0.12208 0.12838 0.11775 -0.00144 -0.00301 -0.00132 75  MET A C   
777  C  C   B MET A 52  ? 0.14313 0.13804 0.11203 -0.02010 -0.00252 0.00414  75  MET A C   
778  O  O   A MET A 52  ? 0.11171 0.12802 0.12208 0.02443  -0.00279 -0.00426 75  MET A O   
779  O  O   B MET A 52  ? 0.15215 0.15877 0.11579 -0.01955 0.00133  -0.00575 75  MET A O   
780  C  CB  A MET A 52  ? 0.11304 0.11854 0.12291 0.00605  -0.00670 -0.01133 75  MET A CB  
781  C  CB  B MET A 52  ? 0.16564 0.13240 0.12701 -0.01017 0.02359  0.01026  75  MET A CB  
782  C  CG  A MET A 52  ? 0.10942 0.12513 0.13694 -0.00377 -0.02216 -0.00974 75  MET A CG  
783  C  CG  B MET A 52  ? 0.20284 0.15746 0.16220 -0.01645 0.02805  0.03406  75  MET A CG  
784  S  SD  A MET A 52  ? 0.13369 0.12332 0.14963 -0.01446 -0.02247 -0.02367 75  MET A SD  
785  S  SD  B MET A 52  ? 0.23948 0.13643 0.19925 0.02039  0.04366  0.03407  75  MET A SD  
786  C  CE  A MET A 52  ? 0.12446 0.09268 0.14556 -0.03191 -0.04250 -0.03497 75  MET A CE  
787  C  CE  B MET A 52  ? 0.22021 0.13959 0.20350 0.03245  0.02185  0.02815  75  MET A CE  
806  N  N   . ALA A 53  ? 0.13900 0.13585 0.11645 -0.02033 0.00495  0.00129  76  ALA A N   
807  C  CA  . ALA A 53  ? 0.14598 0.13409 0.12054 -0.01863 0.00099  -0.00498 76  ALA A CA  
808  C  C   . ALA A 53  ? 0.16243 0.11086 0.12028 -0.00379 -0.00598 -0.00076 76  ALA A C   
809  O  O   . ALA A 53  ? 0.16867 0.12954 0.11657 -0.01184 0.00672  -0.00912 76  ALA A O   
810  C  CB  . ALA A 53  ? 0.16587 0.12593 0.13785 -0.01264 0.01142  0.00306  76  ALA A CB  
817  N  N   . ALA A 54  ? 0.14009 0.13336 0.11265 -0.00067 0.00020  -0.00219 77  ALA A N   
818  C  CA  . ALA A 54  ? 0.12550 0.13602 0.11720 -0.00673 0.00304  0.00667  77  ALA A CA  
819  C  C   . ALA A 54  ? 0.12518 0.12793 0.11438 -0.00824 0.00574  -0.00436 77  ALA A C   
820  O  O   . ALA A 54  ? 0.13797 0.14265 0.11596 -0.00048 0.01435  0.00492  77  ALA A O   
821  C  CB  . ALA A 54  ? 0.13669 0.14925 0.12352 -0.00819 -0.01104 0.00954  77  ALA A CB  
827  N  N   . ALA A 55  ? 0.13458 0.11799 0.11254 -0.00129 0.01154  -0.00154 78  ALA A N   
828  C  CA  . ALA A 55  ? 0.14479 0.11824 0.11402 -0.01559 0.00356  0.00167  78  ALA A CA  
829  C  C   . ALA A 55  ? 0.14416 0.12418 0.10931 0.00025  0.01063  -0.01124 78  ALA A C   
830  O  O   . ALA A 55  ? 0.16223 0.12666 0.10516 -0.00033 0.00850  -0.00216 78  ALA A O   
831  C  CB  . ALA A 55  ? 0.17592 0.12278 0.11917 0.00469  0.01400  0.00120  78  ALA A CB  
837  N  N   . ALA A 56  ? 0.14909 0.12297 0.10898 -0.00193 0.00461  -0.01078 79  ALA A N   
838  C  CA  . ALA A 56  ? 0.16211 0.13141 0.11497 0.00455  -0.00182 -0.01064 79  ALA A CA  
839  C  C   . ALA A 56  ? 0.13834 0.14143 0.11932 0.02213  0.00426  -0.01369 79  ALA A C   
840  O  O   . ALA A 56  ? 0.17352 0.17245 0.11374 0.01358  -0.00155 -0.00433 79  ALA A O   
841  C  CB  . ALA A 56  ? 0.16542 0.13685 0.12300 0.00350  -0.00737 -0.01708 79  ALA A CB  
847  N  N   . VAL A 57  ? 0.15048 0.12556 0.11952 -0.00395 0.01282  -0.00596 80  VAL A N   
848  C  CA  . VAL A 57  ? 0.16613 0.13449 0.13282 0.01343  0.00795  -0.00262 80  VAL A CA  
849  C  C   . VAL A 57  ? 0.15931 0.14260 0.11816 0.01765  0.00014  -0.01840 80  VAL A C   
850  O  O   . VAL A 57  ? 0.18333 0.16297 0.11757 0.01399  0.01962  -0.01759 80  VAL A O   
851  C  CB  . VAL A 57  ? 0.16204 0.14211 0.16220 0.01366  0.00337  0.00193  80  VAL A CB  
852  C  CG1 . VAL A 57  ? 0.17362 0.15333 0.17759 0.01521  0.01331  0.02249  80  VAL A CG1 
853  C  CG2 . VAL A 57  ? 0.20076 0.16047 0.16881 0.01500  0.00498  0.00716  80  VAL A CG2 
863  N  N   . LEU A 58  ? 0.15881 0.12549 0.12151 0.00285  0.01045  -0.00471 81  LEU A N   
864  C  CA  . LEU A 58  ? 0.14970 0.14231 0.13130 0.01279  0.01059  0.00960  81  LEU A CA  
865  C  C   . LEU A 58  ? 0.17188 0.15176 0.12136 0.00235  0.01444  0.00410  81  LEU A C   
866  O  O   . LEU A 58  ? 0.19311 0.15439 0.12723 0.00070  0.02817  0.01127  81  LEU A O   
867  C  CB  . LEU A 58  ? 0.14992 0.14091 0.13859 0.00421  0.01670  0.01031  81  LEU A CB  
868  C  CG  . LEU A 58  ? 0.16015 0.12576 0.14001 -0.01115 0.02215  0.00737  81  LEU A CG  
869  C  CD1 . LEU A 58  ? 0.14792 0.13613 0.14376 -0.00738 0.01913  0.00047  81  LEU A CD1 
870  C  CD2 . LEU A 58  ? 0.19200 0.15293 0.13199 -0.00551 0.01279  0.01354  81  LEU A CD2 
882  N  N   B LYS A 59  ? 0.16393 0.15990 0.11698 0.00541  0.01273  0.00770  82  LYS A N   
883  N  N   C LYS A 59  ? 0.17560 0.15901 0.12206 0.00627  0.01189  0.00656  82  LYS A N   
884  C  CA  B LYS A 59  ? 0.18847 0.17071 0.11857 0.02019  0.00413  -0.00020 82  LYS A CA  
885  C  CA  C LYS A 59  ? 0.18499 0.16776 0.12388 0.01324  0.00789  0.00684  82  LYS A CA  
886  C  C   B LYS A 59  ? 0.20467 0.17753 0.11851 0.02002  0.00592  -0.00351 82  LYS A C   
887  C  C   C LYS A 59  ? 0.19048 0.17023 0.12348 0.01091  0.01007  0.00077  82  LYS A C   
888  O  O   B LYS A 59  ? 0.23354 0.20271 0.12259 0.01939  0.02241  0.01362  82  LYS A O   
889  O  O   C LYS A 59  ? 0.19718 0.17714 0.12455 0.00874  0.01358  0.00465  82  LYS A O   
890  C  CB  B LYS A 59  ? 0.20474 0.18535 0.12568 0.02993  -0.00387 0.00057  82  LYS A CB  
891  C  CB  C LYS A 59  ? 0.19120 0.17557 0.12694 0.02099  0.00153  0.01535  82  LYS A CB  
892  C  CG  B LYS A 59  ? 0.24170 0.22606 0.14866 0.04257  -0.01142 0.01231  82  LYS A CG  
893  C  CG  C LYS A 59  ? 0.20301 0.18884 0.13282 0.02660  -0.00501 0.02583  82  LYS A CG  
894  C  CD  B LYS A 59  ? 0.30179 0.29204 0.18049 0.01943  -0.01038 0.03606  82  LYS A CD  
895  C  CD  C LYS A 59  ? 0.22588 0.20906 0.14081 0.02359  -0.01079 0.03935  82  LYS A CD  
896  C  CE  B LYS A 59  ? 0.36477 0.35297 0.20835 0.01069  -0.00578 0.02957  82  LYS A CE  
897  C  CE  C LYS A 59  ? 0.24965 0.22264 0.14714 0.02441  -0.01244 0.03425  82  LYS A CE  
898  N  NZ  B LYS A 59  ? 0.38599 0.38943 0.22479 0.00777  -0.00981 0.02393  82  LYS A NZ  
899  N  NZ  C LYS A 59  ? 0.25732 0.23459 0.15090 0.03228  -0.01584 0.03349  82  LYS A NZ  
926  N  N   . LYS A 60  ? 0.19249 0.16319 0.12445 0.00732  0.01324  -0.00562 83  LYS A N   
927  C  CA  . LYS A 60  ? 0.21047 0.18481 0.14540 0.02338  0.01977  -0.01624 83  LYS A CA  
928  C  C   . LYS A 60  ? 0.21933 0.17070 0.14423 0.02195  0.02757  -0.01794 83  LYS A C   
929  O  O   . LYS A 60  ? 0.23252 0.22099 0.14521 0.01054  0.03785  -0.02182 83  LYS A O   
930  C  CB  . LYS A 60  ? 0.22005 0.17658 0.16164 0.00585  0.00824  -0.03286 83  LYS A CB  
931  C  CG  . LYS A 60  ? 0.24984 0.18394 0.18717 0.01168  0.00326  -0.02568 83  LYS A CG  
932  C  CD  . LYS A 60  ? 0.28524 0.18362 0.21423 -0.02505 0.00653  -0.03390 83  LYS A CD  
933  C  CE  . LYS A 60  ? 0.34995 0.24002 0.23919 -0.02473 0.01809  -0.02489 83  LYS A CE  
934  N  NZ  . LYS A 60  ? 0.37767 0.24396 0.24535 -0.02292 0.02995  -0.02514 83  LYS A NZ  
948  N  N   . SER A 61  ? 0.19891 0.16234 0.15519 0.00089  0.02548  -0.02749 84  SER A N   
949  C  CA  . SER A 61  ? 0.20893 0.17078 0.16585 0.00111  0.02695  -0.01244 84  SER A CA  
950  C  C   . SER A 61  ? 0.23234 0.19770 0.16813 0.02869  0.05882  -0.01307 84  SER A C   
951  O  O   . SER A 61  ? 0.25665 0.22154 0.17223 0.04092  0.07303  -0.01064 84  SER A O   
952  C  CB  . SER A 61  ? 0.19191 0.16373 0.17222 0.01033  0.01776  -0.01291 84  SER A CB  
953  O  OG  . SER A 61  ? 0.18950 0.19267 0.18161 -0.00562 0.02368  -0.01422 84  SER A OG  
959  N  N   . GLU A 62  ? 0.24901 0.19200 0.17505 0.01475  0.06724  0.00018  85  GLU A N   
960  C  CA  . GLU A 62  ? 0.28155 0.19174 0.17421 0.00415  0.08051  -0.00162 85  GLU A CA  
961  C  C   . GLU A 62  ? 0.32930 0.21478 0.17627 0.02082  0.06994  0.00057  85  GLU A C   
962  O  O   . GLU A 62  ? 0.37718 0.25199 0.19092 0.00138  0.08587  0.00879  85  GLU A O   
963  C  CB  . GLU A 62  ? 0.31124 0.18976 0.18132 0.01259  0.08120  0.00723  85  GLU A CB  
964  C  CG  . GLU A 62  ? 0.33817 0.19198 0.19823 0.00658  0.09989  -0.00537 85  GLU A CG  
965  C  CD  . GLU A 62  ? 0.37630 0.22215 0.22671 0.01949  0.09408  -0.00299 85  GLU A CD  
966  O  OE1 . GLU A 62  ? 0.40311 0.26200 0.24401 0.09807  0.09189  0.00997  85  GLU A OE1 
967  O  OE2 . GLU A 62  ? 0.36154 0.23490 0.23906 -0.01099 0.11118  -0.03749 85  GLU A OE2 
974  N  N   A SER A 63  ? 0.34551 0.23051 0.16713 0.03002  0.05847  -0.02501 86  SER A N   
975  N  N   B SER A 63  ? 0.33589 0.23013 0.17366 0.03991  0.06681  -0.01848 86  SER A N   
976  C  CA  A SER A 63  ? 0.37456 0.27846 0.17807 0.03250  0.05419  -0.03583 86  SER A CA  
977  C  CA  B SER A 63  ? 0.34750 0.26168 0.18115 0.05304  0.06699  -0.03073 86  SER A CA  
978  C  C   A SER A 63  ? 0.38766 0.27649 0.18510 0.03455  0.07214  -0.04604 86  SER A C   
979  C  C   B SER A 63  ? 0.37160 0.26184 0.18879 0.04527  0.07300  -0.03905 86  SER A C   
980  O  O   A SER A 63  ? 0.42490 0.32432 0.18513 0.04034  0.07241  -0.04468 86  SER A O   
981  O  O   B SER A 63  ? 0.39751 0.28616 0.18821 0.04540  0.07083  -0.03954 86  SER A O   
982  C  CB  A SER A 63  ? 0.38888 0.32258 0.18301 0.02396  0.02842  -0.03640 86  SER A CB  
983  C  CB  B SER A 63  ? 0.33621 0.28914 0.18176 0.06982  0.05849  -0.03385 86  SER A CB  
984  O  OG  A SER A 63  ? 0.41270 0.35170 0.18795 0.01213  0.00562  -0.02760 86  SER A OG  
985  O  OG  B SER A 63  ? 0.33519 0.29759 0.18344 0.08161  0.05021  -0.03258 86  SER A OG  
996  N  N   . GLU A 64  ? 0.37704 0.24862 0.20166 0.04440  0.07061  -0.03363 87  GLU A N   
997  C  CA  . GLU A 64  ? 0.38438 0.26007 0.21899 0.01464  0.06814  -0.04053 87  GLU A CA  
998  C  C   . GLU A 64  ? 0.39155 0.30739 0.22229 -0.01942 0.06378  -0.04312 87  GLU A C   
999  O  O   . GLU A 64  ? 0.39456 0.24182 0.22607 -0.00520 0.06649  -0.04462 87  GLU A O   
1000 C  CB  . GLU A 64  ? 0.40636 0.28859 0.23551 -0.01577 0.05897  -0.03118 87  GLU A CB  
1001 C  CG  . GLU A 64  ? 0.46591 0.31775 0.25032 -0.03191 0.05390  -0.03458 87  GLU A CG  
1002 C  CD  . GLU A 64  ? 0.51218 0.35524 0.26994 -0.04637 0.05143  -0.03983 87  GLU A CD  
1003 O  OE1 . GLU A 64  ? 0.54939 0.38865 0.27717 -0.06317 0.04088  -0.00823 87  GLU A OE1 
1004 O  OE2 . GLU A 64  ? 0.51494 0.36279 0.27772 -0.04595 0.06288  -0.06588 87  GLU A OE2 
1011 N  N   A PRO A 65  ? 0.40190 0.37351 0.22917 -0.02039 0.06193  -0.03182 88  PRO A N   
1012 N  N   B PRO A 65  ? 0.40951 0.40102 0.22768 -0.10083 0.04074  -0.02520 88  PRO A N   
1013 C  CA  A PRO A 65  ? 0.40406 0.41258 0.23745 0.00027  0.06778  -0.02279 88  PRO A CA  
1014 C  CA  B PRO A 65  ? 0.42317 0.46170 0.23613 -0.12279 0.03358  -0.00788 88  PRO A CA  
1015 C  C   A PRO A 65  ? 0.37312 0.42318 0.23794 0.03053  0.07933  -0.02321 88  PRO A C   
1016 C  C   B PRO A 65  ? 0.39641 0.49270 0.23072 -0.11900 0.02931  0.00127  88  PRO A C   
1017 O  O   A PRO A 65  ? 0.37978 0.42763 0.24213 0.03617  0.07538  -0.02003 88  PRO A O   
1018 O  O   B PRO A 65  ? 0.41539 0.52432 0.24315 -0.16321 0.01138  0.00849  88  PRO A O   
1019 C  CB  A PRO A 65  ? 0.41835 0.42524 0.23839 -0.00710 0.06647  -0.02263 88  PRO A CB  
1020 C  CB  B PRO A 65  ? 0.43664 0.47795 0.24123 -0.12719 0.03744  -0.00588 88  PRO A CB  
1021 C  CG  A PRO A 65  ? 0.41591 0.42209 0.23601 -0.00803 0.06596  -0.02700 88  PRO A CG  
1022 C  CG  B PRO A 65  ? 0.43307 0.47747 0.23954 -0.11270 0.03755  -0.01138 88  PRO A CG  
1023 C  CD  A PRO A 65  ? 0.41070 0.40302 0.23161 -0.01401 0.06546  -0.02887 88  PRO A CD  
1024 C  CD  B PRO A 65  ? 0.42588 0.45046 0.23269 -0.11052 0.04117  -0.01691 88  PRO A CD  
1039 N  N   A ASN A 66  ? 0.33722 0.42427 0.23330 0.04047  0.08993  -0.02580 89  ASN A N   
1040 N  N   B ASN A 66  ? 0.34415 0.48464 0.22417 -0.06833 0.04170  -0.00136 89  ASN A N   
1041 C  CA  A ASN A 66  ? 0.31338 0.42736 0.23239 0.01156  0.08033  -0.01356 89  ASN A CA  
1042 C  CA  B ASN A 66  ? 0.31614 0.48192 0.22582 -0.01051 0.03763  -0.00909 89  ASN A CA  
1043 C  C   A ASN A 66  ? 0.27203 0.40792 0.22622 0.03160  0.06350  -0.01701 89  ASN A C   
1044 C  C   B ASN A 66  ? 0.25431 0.44006 0.21784 0.03212  0.04569  -0.00776 89  ASN A C   
1045 O  O   A ASN A 66  ? 0.28338 0.42309 0.22884 0.04127  0.05516  -0.02072 89  ASN A O   
1046 O  O   B ASN A 66  ? 0.24451 0.46777 0.21283 0.07196  0.03486  0.00198  89  ASN A O   
1047 C  CB  A ASN A 66  ? 0.31926 0.43088 0.23597 -0.04308 0.08084  0.00118  89  ASN A CB  
1048 C  CB  B ASN A 66  ? 0.35490 0.51858 0.23855 -0.00341 0.02748  -0.00694 89  ASN A CB  
1049 C  CG  A ASN A 66  ? 0.32105 0.42780 0.23897 -0.08006 0.07756  0.02023  89  ASN A CG  
1050 C  CG  B ASN A 66  ? 0.39263 0.55411 0.25424 -0.00261 0.02514  -0.01198 89  ASN A CG  
1051 O  OD1 A ASN A 66  ? 0.33518 0.43067 0.24578 -0.10461 0.05814  0.02970  89  ASN A OD1 
1052 O  OD1 B ASN A 66  ? 0.40994 0.56777 0.26216 0.01058  0.02608  -0.01773 89  ASN A OD1 
1053 N  ND2 A ASN A 66  ? 0.31495 0.42607 0.23881 -0.06833 0.08832  0.02324  89  ASN A ND2 
1054 N  ND2 B ASN A 66  ? 0.41044 0.56064 0.25890 -0.01558 0.01785  -0.01093 89  ASN A ND2 
1067 N  N   . LEU A 67  ? 0.24221 0.37561 0.21850 0.03895  0.03957  -0.01345 90  LEU A N   
1068 C  CA  . LEU A 67  ? 0.20708 0.24942 0.21478 0.02702  0.01613  -0.02705 90  LEU A CA  
1069 C  C   . LEU A 67  ? 0.19407 0.21247 0.20864 0.03040  0.01876  -0.02663 90  LEU A C   
1070 O  O   . LEU A 67  ? 0.19265 0.20313 0.20864 0.01464  0.01764  -0.03218 90  LEU A O   
1071 C  CB  . LEU A 67  ? 0.21850 0.21847 0.22749 0.00825  -0.01105 -0.02939 90  LEU A CB  
1072 C  CG  . LEU A 67  ? 0.22341 0.19095 0.24708 0.00046  -0.01830 -0.05281 90  LEU A CG  
1073 C  CD1 . LEU A 67  ? 0.25532 0.21729 0.26886 0.00290  -0.03164 -0.05531 90  LEU A CD1 
1074 C  CD2 . LEU A 67  ? 0.21803 0.22404 0.25804 0.00323  -0.01328 -0.02517 90  LEU A CD2 
1086 N  N   . LEU A 68  ? 0.18826 0.19337 0.19805 0.00704  0.03026  0.00311  91  LEU A N   
1087 C  CA  . LEU A 68  ? 0.19258 0.16379 0.19858 0.02245  0.02549  0.02058  91  LEU A CA  
1088 C  C   . LEU A 68  ? 0.17113 0.15768 0.19860 -0.00501 0.02926  0.02289  91  LEU A C   
1089 O  O   . LEU A 68  ? 0.17604 0.17202 0.19658 0.02199  0.02323  0.00710  91  LEU A O   
1090 C  CB  . LEU A 68  ? 0.21126 0.18550 0.21750 0.03850  0.02355  -0.00097 91  LEU A CB  
1091 C  CG  . LEU A 68  ? 0.23443 0.23056 0.24314 0.03264  0.02934  -0.01209 91  LEU A CG  
1092 C  CD1 . LEU A 68  ? 0.27010 0.22836 0.25698 0.02475  0.02373  -0.01888 91  LEU A CD1 
1093 C  CD2 . LEU A 68  ? 0.24270 0.26734 0.25743 0.03901  0.05095  -0.02272 91  LEU A CD2 
1105 N  N   . ASN A 69  ? 0.16362 0.17295 0.20641 0.00150  0.04640  0.00890  92  ASN A N   
1106 C  CA  . ASN A 69  ? 0.16724 0.19484 0.23324 -0.01049 0.05325  0.01624  92  ASN A CA  
1107 C  C   . ASN A 69  ? 0.17013 0.17389 0.23014 0.00422  0.05940  0.00079  92  ASN A C   
1108 O  O   . ASN A 69  ? 0.18188 0.18206 0.23844 0.01266  0.03762  -0.00221 92  ASN A O   
1109 C  CB  . ASN A 69  ? 0.16793 0.20704 0.27435 0.00498  0.05592  0.02786  92  ASN A CB  
1110 C  CG  . ASN A 69  ? 0.23934 0.23067 0.30832 -0.03476 0.06775  0.03001  92  ASN A CG  
1111 O  OD1 . ASN A 69  ? 0.26949 0.26648 0.32838 -0.03950 0.04546  0.00929  92  ASN A OD1 
1112 N  ND2 . ASN A 69  ? 0.30426 0.29295 0.32901 -0.08669 0.07243  0.03626  92  ASN A ND2 
1119 N  N   . GLN A 70  ? 0.18180 0.17090 0.21795 0.00118  0.06027  -0.00368 93  GLN A N   
1120 C  CA  . GLN A 70  ? 0.19545 0.17534 0.22160 -0.01793 0.03933  -0.02136 93  GLN A CA  
1121 C  C   . GLN A 70  ? 0.19654 0.17241 0.20750 -0.03409 0.04060  -0.01617 93  GLN A C   
1122 O  O   . GLN A 70  ? 0.21206 0.18851 0.19694 -0.02460 0.04460  -0.03176 93  GLN A O   
1123 C  CB  . GLN A 70  ? 0.25274 0.20086 0.24927 -0.03216 0.02181  -0.02877 93  GLN A CB  
1124 C  CG  . GLN A 70  ? 0.30792 0.25026 0.27473 -0.02714 0.01344  -0.04044 93  GLN A CG  
1125 C  CD  . GLN A 70  ? 0.36092 0.29436 0.29691 -0.03230 -0.00165 -0.03411 93  GLN A CD  
1126 O  OE1 . GLN A 70  ? 0.40056 0.31240 0.32061 -0.01533 -0.02054 -0.03905 93  GLN A OE1 
1127 N  NE2 . GLN A 70  ? 0.35827 0.33515 0.29933 -0.02340 0.01627  -0.03422 93  GLN A NE2 
1136 N  N   . ARG A 71  ? 0.24168 0.15417 0.21225 -0.02879 0.04268  0.01343  94  ARG A N   
1137 C  CA  . ARG A 71  ? 0.23527 0.16564 0.22431 -0.01747 0.05373  0.00978  94  ARG A CA  
1138 C  C   . ARG A 71  ? 0.20539 0.17784 0.21958 -0.02028 0.04996  -0.02086 94  ARG A C   
1139 O  O   . ARG A 71  ? 0.24194 0.22349 0.22010 -0.06659 0.05583  -0.01976 94  ARG A O   
1140 C  CB  . ARG A 71  ? 0.22376 0.20111 0.25577 0.00236  0.05815  0.01289  94  ARG A CB  
1141 C  CG  . ARG A 71  ? 0.23348 0.20207 0.27590 0.01810  0.05998  0.00484  94  ARG A CG  
1142 C  CD  . ARG A 71  ? 0.22247 0.16839 0.29356 -0.00073 0.05210  0.00421  94  ARG A CD  
1143 N  NE  . ARG A 71  ? 0.18378 0.16867 0.31044 0.01169  0.04759  0.01342  94  ARG A NE  
1144 C  CZ  . ARG A 71  ? 0.15953 0.17981 0.31611 0.03468  0.02702  0.03467  94  ARG A CZ  
1145 N  NH1 . ARG A 71  ? 0.19416 0.16372 0.31308 0.00422  0.02033  0.04667  94  ARG A NH1 
1146 N  NH2 . ARG A 71  ? 0.16439 0.19290 0.32463 0.01281  0.02784  0.05357  94  ARG A NH2 
1160 N  N   . VAL A 72  ? 0.19122 0.15812 0.22046 -0.00140 0.04251  -0.02355 95  VAL A N   
1161 C  CA  . VAL A 72  ? 0.17298 0.17014 0.22772 -0.00004 0.04281  -0.00904 95  VAL A CA  
1162 C  C   . VAL A 72  ? 0.15720 0.15986 0.22973 0.00125  0.05498  -0.01042 95  VAL A C   
1163 O  O   . VAL A 72  ? 0.17325 0.15136 0.22653 -0.00328 0.03633  -0.00152 95  VAL A O   
1164 C  CB  . VAL A 72  ? 0.18982 0.17591 0.22589 0.04175  0.04539  0.00686  95  VAL A CB  
1165 C  CG1 . VAL A 72  ? 0.19818 0.20517 0.23834 0.01910  0.07302  0.00337  95  VAL A CG1 
1166 C  CG2 . VAL A 72  ? 0.19481 0.19462 0.22297 0.03122  0.03983  0.00116  95  VAL A CG2 
1176 N  N   . GLU A 73  ? 0.17434 0.16041 0.23496 -0.00170 0.06348  -0.01644 96  GLU A N   
1177 C  CA  . GLU A 73  ? 0.22320 0.14746 0.23725 0.00987  0.07070  -0.01574 96  GLU A CA  
1178 C  C   . GLU A 73  ? 0.17739 0.12967 0.22137 -0.00004 0.05299  -0.01409 96  GLU A C   
1179 O  O   . GLU A 73  ? 0.19166 0.15767 0.22031 -0.00337 0.05644  -0.00751 96  GLU A O   
1180 C  CB  . GLU A 73  ? 0.33033 0.15357 0.26136 0.02786  0.09692  -0.00180 96  GLU A CB  
1181 C  CG  . GLU A 73  ? 0.46728 0.23912 0.28223 0.03709  0.10094  -0.00361 96  GLU A CG  
1182 C  CD  . GLU A 73  ? 0.61066 0.33791 0.29799 0.04277  0.10477  -0.00952 96  GLU A CD  
1183 O  OE1 . GLU A 73  ? 0.69576 0.36887 0.30416 0.02271  0.10050  -0.00601 96  GLU A OE1 
1184 O  OE2 . GLU A 73  ? 0.64282 0.39563 0.30711 0.05979  0.11491  -0.02741 96  GLU A OE2 
1191 N  N   . ILE A 74  ? 0.17872 0.12993 0.23067 0.00099  0.03984  0.00505  97  ILE A N   
1192 C  CA  . ILE A 74  ? 0.16679 0.12740 0.23578 0.00894  0.02455  0.00621  97  ILE A CA  
1193 C  C   . ILE A 74  ? 0.18131 0.14325 0.23838 0.01926  0.01510  -0.00271 97  ILE A C   
1194 O  O   . ILE A 74  ? 0.18973 0.17101 0.26904 0.02567  0.00424  0.00403  97  ILE A O   
1195 C  CB  . ILE A 74  ? 0.18538 0.14687 0.24312 0.00541  0.01504  0.00461  97  ILE A CB  
1196 C  CG1 . ILE A 74  ? 0.19646 0.15506 0.25486 0.00797  0.00515  -0.00005 97  ILE A CG1 
1197 C  CG2 . ILE A 74  ? 0.20350 0.15713 0.24355 0.02927  0.01526  0.01223  97  ILE A CG2 
1198 C  CD1 . ILE A 74  ? 0.19711 0.15369 0.25666 0.00070  0.01061  -0.00113 97  ILE A CD1 
1210 N  N   . LYS A 75  ? 0.19801 0.12984 0.22517 0.01063  0.02608  0.00593  98  LYS A N   
1211 C  CA  . LYS A 75  ? 0.22511 0.15312 0.21819 0.00929  0.02294  0.01621  98  LYS A CA  
1212 C  C   . LYS A 75  ? 0.18756 0.12428 0.21068 0.01596  0.00620  0.00678  98  LYS A C   
1213 O  O   . LYS A 75  ? 0.18392 0.12455 0.20329 0.00841  0.00556  0.01365  98  LYS A O   
1214 C  CB  . LYS A 75  ? 0.28939 0.19278 0.21780 -0.00341 0.03476  0.00812  98  LYS A CB  
1215 C  CG  . LYS A 75  ? 0.35285 0.22734 0.22037 -0.01703 0.03717  0.00681  98  LYS A CG  
1216 C  CD  . LYS A 75  ? 0.39562 0.28017 0.22612 -0.00579 0.03095  0.00590  98  LYS A CD  
1217 C  CE  . LYS A 75  ? 0.41042 0.27776 0.22913 0.03394  0.02064  0.01754  98  LYS A CE  
1218 N  NZ  . LYS A 75  ? 0.39751 0.26415 0.22737 0.06854  0.02426  0.02933  98  LYS A NZ  
1232 N  N   . LYS A 76  ? 0.19748 0.13039 0.21146 0.02757  0.00487  -0.00186 99  LYS A N   
1233 C  CA  . LYS A 76  ? 0.25693 0.12789 0.21816 0.02727  0.01145  0.01044  99  LYS A CA  
1234 C  C   . LYS A 76  ? 0.22210 0.11131 0.20208 0.00391  0.01123  0.00686  99  LYS A C   
1235 O  O   . LYS A 76  ? 0.22112 0.12834 0.19537 0.00078  0.01507  0.01204  99  LYS A O   
1236 C  CB  . LYS A 76  ? 0.35878 0.16639 0.24881 0.02740  0.00214  0.02998  99  LYS A CB  
1237 C  CG  . LYS A 76  ? 0.48135 0.23968 0.28012 0.03424  -0.01476 0.04525  99  LYS A CG  
1238 C  CD  . LYS A 76  ? 0.57224 0.33954 0.28936 0.01047  -0.01929 0.04950  99  LYS A CD  
1239 C  CE  . LYS A 76  ? 0.62846 0.42558 0.29929 -0.00740 -0.02713 0.02224  99  LYS A CE  
1240 N  NZ  . LYS A 76  ? 0.66464 0.46298 0.30047 -0.01155 -0.03952 0.01693  99  LYS A NZ  
1254 N  N   . SER A 77  ? 0.23104 0.11436 0.19530 -0.00445 0.01738  -0.00320 100 SER A N   
1255 C  CA  . SER A 77  ? 0.22630 0.13697 0.20182 -0.01352 0.00864  -0.01735 100 SER A CA  
1256 C  C   . SER A 77  ? 0.18380 0.14016 0.19160 -0.00660 0.00488  -0.02794 100 SER A C   
1257 O  O   . SER A 77  ? 0.19047 0.16862 0.20621 -0.00988 0.00785  -0.03180 100 SER A O   
1258 C  CB  . SER A 77  ? 0.23305 0.14775 0.20482 -0.02654 0.00598  -0.03142 100 SER A CB  
1259 O  OG  . SER A 77  ? 0.27569 0.17737 0.20571 0.00307  0.00249  -0.03395 100 SER A OG  
1265 N  N   . ASP A 78  ? 0.18317 0.13628 0.17617 0.00268  0.01242  -0.01665 101 ASP A N   
1266 C  CA  . ASP A 78  ? 0.16256 0.11579 0.16978 0.00579  -0.00469 -0.00228 101 ASP A CA  
1267 C  C   . ASP A 78  ? 0.16741 0.11577 0.16761 -0.00048 -0.00581 0.00651  101 ASP A C   
1268 O  O   . ASP A 78  ? 0.20641 0.12208 0.16067 0.00782  -0.00457 -0.00967 101 ASP A O   
1269 C  CB  . ASP A 78  ? 0.18619 0.11506 0.16654 0.00064  -0.01132 0.00060  101 ASP A CB  
1270 C  CG  . ASP A 78  ? 0.17610 0.13463 0.17386 0.00003  0.00591  -0.00527 101 ASP A CG  
1271 O  OD1 . ASP A 78  ? 0.19255 0.17680 0.17198 0.01856  -0.00267 -0.01682 101 ASP A OD1 
1272 O  OD2 . ASP A 78  ? 0.18144 0.17129 0.18181 -0.00826 0.01372  -0.00491 101 ASP A OD2 
1277 N  N   . LEU A 79  ? 0.16520 0.11406 0.16355 0.00064  -0.01673 0.00179  102 LEU A N   
1278 C  CA  . LEU A 79  ? 0.17383 0.11159 0.16313 -0.01280 -0.01521 0.00574  102 LEU A CA  
1279 C  C   . LEU A 79  ? 0.19017 0.11080 0.16746 -0.01950 -0.00197 0.00941  102 LEU A C   
1280 O  O   . LEU A 79  ? 0.21143 0.11733 0.17570 0.00112  0.00677  0.00656  102 LEU A O   
1281 C  CB  . LEU A 79  ? 0.18578 0.13539 0.17278 0.00657  -0.02261 0.00737  102 LEU A CB  
1282 C  CG  . LEU A 79  ? 0.19051 0.13394 0.18631 0.00342  -0.03622 0.00904  102 LEU A CG  
1283 C  CD1 . LEU A 79  ? 0.21197 0.18403 0.19907 0.01511  -0.02692 0.02704  102 LEU A CD1 
1284 C  CD2 . LEU A 79  ? 0.20207 0.14986 0.20820 0.00299  -0.02698 0.00296  102 LEU A CD2 
1296 N  N   . VAL A 80  ? 0.20282 0.12095 0.17806 -0.00547 -0.00014 -0.00337 103 VAL A N   
1297 C  CA  . VAL A 80  ? 0.22408 0.12505 0.18431 -0.01324 0.00943  -0.00100 103 VAL A CA  
1298 C  C   . VAL A 80  ? 0.25710 0.12349 0.18490 -0.00120 0.01520  0.02777  103 VAL A C   
1299 O  O   . VAL A 80  ? 0.28894 0.16831 0.19333 -0.01216 -0.00511 0.03056  103 VAL A O   
1300 C  CB  . VAL A 80  ? 0.22023 0.14820 0.19601 0.01085  0.01459  0.00091  103 VAL A CB  
1301 C  CG1 . VAL A 80  ? 0.23440 0.16944 0.20076 0.02273  0.01652  0.01756  103 VAL A CG1 
1302 C  CG2 . VAL A 80  ? 0.25595 0.13290 0.21334 0.00452  0.00354  0.00470  103 VAL A CG2 
1312 N  N   . ASN A 81  ? 0.28424 0.18331 0.18189 -0.01964 0.01030  0.01538  104 ASN A N   
1313 C  CA  . ASN A 81  ? 0.30085 0.23530 0.18907 -0.03812 0.00484  0.01324  104 ASN A CA  
1314 C  C   . ASN A 81  ? 0.32256 0.27481 0.18263 -0.05161 -0.00341 0.02158  104 ASN A C   
1315 O  O   . ASN A 81  ? 0.39256 0.38336 0.18609 -0.10338 0.00307  0.03701  104 ASN A O   
1316 C  CB  . ASN A 81  ? 0.29931 0.25541 0.20454 -0.02135 0.02068  -0.01432 104 ASN A CB  
1317 C  CG  . ASN A 81  ? 0.32842 0.23949 0.21733 0.02906  0.00761  -0.02736 104 ASN A CG  
1318 O  OD1 . ASN A 81  ? 0.27149 0.17352 0.23332 0.02207  -0.01104 -0.04111 104 ASN A OD1 
1319 N  ND2 . ASN A 81  ? 0.38405 0.22175 0.21232 0.03524  -0.00643 -0.02589 104 ASN A ND2 
1326 N  N   . TYR A 82  ? 0.24022 0.18106 0.17362 -0.02207 -0.00998 0.01987  105 TYR A N   
1327 C  CA  . TYR A 82  ? 0.21975 0.19550 0.16487 0.00074  -0.00285 0.00599  105 TYR A CA  
1328 C  C   . TYR A 82  ? 0.20073 0.17067 0.14865 -0.00926 -0.01341 0.02552  105 TYR A C   
1329 O  O   . TYR A 82  ? 0.21350 0.17103 0.15544 0.01673  -0.02997 0.02842  105 TYR A O   
1330 C  CB  . TYR A 82  ? 0.25441 0.19494 0.17407 0.01910  0.00852  0.00739  105 TYR A CB  
1331 C  CG  . TYR A 82  ? 0.29188 0.19699 0.17085 0.01160  0.00160  0.01264  105 TYR A CG  
1332 C  CD1 . TYR A 82  ? 0.35485 0.21696 0.17487 -0.04285 -0.01653 0.01499  105 TYR A CD1 
1333 C  CD2 . TYR A 82  ? 0.29291 0.17834 0.17305 0.02262  0.00324  0.00739  105 TYR A CD2 
1334 C  CE1 . TYR A 82  ? 0.38492 0.22711 0.18460 -0.06015 -0.01911 0.00300  105 TYR A CE1 
1335 C  CE2 . TYR A 82  ? 0.33912 0.17706 0.18402 -0.00114 0.00668  -0.00052 105 TYR A CE2 
1336 C  CZ  . TYR A 82  ? 0.39768 0.22555 0.19455 -0.05460 -0.01090 -0.00216 105 TYR A CZ  
1337 O  OH  . TYR A 82  ? 0.44842 0.26312 0.20828 -0.07825 -0.01797 -0.01006 105 TYR A OH  
1347 N  N   . ASN A 83  ? 0.18859 0.18505 0.15045 0.00057  -0.01951 0.00723  106 ASN A N   
1348 C  CA  . ASN A 83  ? 0.21502 0.18934 0.17415 -0.01424 -0.01038 -0.01245 106 ASN A CA  
1349 C  C   . ASN A 83  ? 0.19506 0.14866 0.17843 0.00807  -0.02040 -0.00959 106 ASN A C   
1350 O  O   . ASN A 83  ? 0.21532 0.16373 0.19188 0.01381  0.00370  -0.01328 106 ASN A O   
1351 C  CB  . ASN A 83  ? 0.27016 0.19022 0.18596 -0.00806 0.00609  -0.02248 106 ASN A CB  
1352 C  CG  . ASN A 83  ? 0.28687 0.19119 0.17967 -0.01644 0.01414  -0.00825 106 ASN A CG  
1353 O  OD1 . ASN A 83  ? 0.29419 0.19377 0.16027 -0.02201 -0.00465 0.00799  106 ASN A OD1 
1354 N  ND2 . ASN A 83  ? 0.30027 0.19505 0.18671 -0.00996 0.01128  0.00120  106 ASN A ND2 
1361 N  N   . PRO A 84  ? 0.18412 0.15662 0.18452 0.01456  -0.03022 -0.00624 107 PRO A N   
1362 C  CA  . PRO A 84  ? 0.23968 0.19231 0.18781 -0.00761 -0.03712 0.00083  107 PRO A CA  
1363 C  C   . PRO A 84  ? 0.21518 0.18780 0.18925 0.00241  -0.05480 0.01005  107 PRO A C   
1364 O  O   . PRO A 84  ? 0.23513 0.22793 0.19700 -0.00829 -0.04981 0.03501  107 PRO A O   
1365 C  CB  . PRO A 84  ? 0.28404 0.21512 0.19113 -0.03182 -0.02556 -0.01376 107 PRO A CB  
1366 C  CG  . PRO A 84  ? 0.27266 0.19083 0.19849 -0.00844 -0.00776 -0.01561 107 PRO A CG  
1367 C  CD  . PRO A 84  ? 0.19967 0.15684 0.18722 0.01521  -0.01109 -0.00016 107 PRO A CD  
1375 N  N   . ILE A 85  ? 0.18526 0.16158 0.18801 0.00796  -0.04748 0.00011  108 ILE A N   
1376 C  CA  . ILE A 85  ? 0.17617 0.15537 0.19201 0.02974  -0.05174 -0.00980 108 ILE A CA  
1377 C  C   . ILE A 85  ? 0.17633 0.15339 0.19434 0.02821  -0.05008 -0.01516 108 ILE A C   
1378 O  O   . ILE A 85  ? 0.18402 0.18185 0.21106 0.03658  -0.03686 -0.00769 108 ILE A O   
1379 C  CB  . ILE A 85  ? 0.18753 0.15446 0.19588 0.02097  -0.03216 -0.00511 108 ILE A CB  
1380 C  CG1 . ILE A 85  ? 0.20384 0.15009 0.19739 -0.01530 -0.03557 -0.01085 108 ILE A CG1 
1381 C  CG2 . ILE A 85  ? 0.18143 0.18871 0.20489 0.02046  -0.02396 -0.00348 108 ILE A CG2 
1382 C  CD1 . ILE A 85  ? 0.23023 0.18315 0.20890 -0.02001 -0.03255 -0.01127 108 ILE A CD1 
1394 N  N   . ALA A 86  ? 0.17540 0.14947 0.18606 0.02746  -0.03196 -0.02401 109 ALA A N   
1395 C  CA  . ALA A 86  ? 0.18120 0.15455 0.20213 0.03863  -0.03292 -0.03358 109 ALA A CA  
1396 C  C   . ALA A 86  ? 0.17704 0.16313 0.22554 0.02634  -0.03064 -0.02777 109 ALA A C   
1397 O  O   . ALA A 86  ? 0.19813 0.16438 0.23454 0.03489  -0.01723 -0.02948 109 ALA A O   
1398 C  CB  . ALA A 86  ? 0.19141 0.16782 0.20654 0.03276  -0.03954 -0.03795 109 ALA A CB  
1404 N  N   . GLU A 87  ? 0.20501 0.15745 0.23961 0.03295  -0.03341 -0.01003 110 GLU A N   
1405 C  CA  . GLU A 87  ? 0.24003 0.17302 0.26391 0.05145  -0.03192 -0.00620 110 GLU A CA  
1406 C  C   . GLU A 87  ? 0.22295 0.18736 0.29427 0.07040  -0.05244 0.00799  110 GLU A C   
1407 O  O   . GLU A 87  ? 0.26030 0.22310 0.31771 0.07571  -0.04245 0.00584  110 GLU A O   
1408 C  CB  . GLU A 87  ? 0.29034 0.17471 0.26145 0.03117  -0.02514 0.00470  110 GLU A CB  
1409 C  CG  . GLU A 87  ? 0.33415 0.18136 0.26365 0.02732  -0.01549 0.00505  110 GLU A CG  
1410 C  CD  . GLU A 87  ? 0.39131 0.24512 0.26745 -0.01911 -0.01750 -0.00137 110 GLU A CD  
1411 O  OE1 . GLU A 87  ? 0.41097 0.29778 0.27811 -0.04517 -0.00236 -0.00072 110 GLU A OE1 
1412 O  OE2 . GLU A 87  ? 0.43538 0.30635 0.26094 -0.03543 -0.02387 -0.00438 110 GLU A OE2 
1419 N  N   . LYS A 88  ? 0.18545 0.19528 0.30207 0.04539  -0.05909 -0.00589 111 LYS A N   
1420 C  CA  . LYS A 88  ? 0.18988 0.23887 0.31957 0.04099  -0.06347 -0.01394 111 LYS A CA  
1421 C  C   . LYS A 88  ? 0.17993 0.23399 0.31823 0.07466  -0.04280 -0.01168 111 LYS A C   
1422 O  O   . LYS A 88  ? 0.20048 0.30257 0.32162 0.06931  -0.04373 -0.00952 111 LYS A O   
1423 C  CB  . LYS A 88  ? 0.19479 0.31125 0.34067 0.02762  -0.07530 -0.03459 111 LYS A CB  
1424 C  CG  . LYS A 88  ? 0.25245 0.38986 0.36380 0.00564  -0.07225 -0.04957 111 LYS A CG  
1425 C  CD  . LYS A 88  ? 0.30518 0.46289 0.38267 -0.01860 -0.06867 -0.05478 111 LYS A CD  
1426 C  CE  . LYS A 88  ? 0.37546 0.51508 0.39658 -0.04097 -0.06820 -0.05024 111 LYS A CE  
1427 N  NZ  . LYS A 88  ? 0.42131 0.55455 0.40633 -0.04915 -0.06646 -0.04560 111 LYS A NZ  
1441 N  N   . HIS A 89  ? 0.18650 0.21041 0.31315 0.04397  -0.03080 -0.00802 112 HIS A N   
1442 C  CA  . HIS A 89  ? 0.21718 0.19598 0.30544 0.03000  -0.00716 -0.00645 112 HIS A CA  
1443 C  C   . HIS A 89  ? 0.19402 0.16673 0.29123 0.02322  0.00632  -0.00920 112 HIS A C   
1444 O  O   . HIS A 89  ? 0.20795 0.17310 0.28807 0.02818  0.00268  0.00815  112 HIS A O   
1445 C  CB  . HIS A 89  ? 0.23674 0.18410 0.31468 0.02684  0.00182  -0.00960 112 HIS A CB  
1446 C  CG  . HIS A 89  ? 0.25296 0.19939 0.32701 0.01798  0.01131  -0.01855 112 HIS A CG  
1447 N  ND1 . HIS A 89  ? 0.28286 0.23192 0.33186 -0.01408 0.02117  -0.01276 112 HIS A ND1 
1448 C  CD2 . HIS A 89  ? 0.24073 0.19044 0.33274 -0.00824 0.01790  -0.02818 112 HIS A CD2 
1449 C  CE1 . HIS A 89  ? 0.27466 0.22800 0.33524 -0.03329 0.02154  -0.02229 112 HIS A CE1 
1450 N  NE2 . HIS A 89  ? 0.26211 0.21415 0.33858 -0.00730 0.02639  -0.01900 112 HIS A NE2 
1458 N  N   . VAL A 90  ? 0.21491 0.18337 0.27910 0.01674  0.02129  -0.00352 113 VAL A N   
1459 C  CA  . VAL A 90  ? 0.19393 0.17446 0.27357 0.01465  0.02797  -0.00274 113 VAL A CA  
1460 C  C   . VAL A 90  ? 0.18115 0.18015 0.27226 0.02448  0.03156  0.01400  113 VAL A C   
1461 O  O   . VAL A 90  ? 0.19704 0.19309 0.26906 0.02904  0.00084  0.00952  113 VAL A O   
1462 C  CB  . VAL A 90  ? 0.22852 0.18119 0.27201 0.00923  0.03997  -0.00657 113 VAL A CB  
1463 C  CG1 . VAL A 90  ? 0.27477 0.18952 0.27635 0.01471  0.02927  -0.00866 113 VAL A CG1 
1464 C  CG2 . VAL A 90  ? 0.26825 0.22310 0.27320 -0.00489 0.04904  -0.01009 113 VAL A CG2 
1474 N  N   . ASN A 91  ? 0.19414 0.17084 0.27945 0.01513  0.03661  0.02069  114 ASN A N   
1475 C  CA  . ASN A 91  ? 0.20520 0.18027 0.29046 0.04644  0.04409  0.02017  114 ASN A CA  
1476 C  C   . ASN A 91  ? 0.22265 0.18150 0.28610 0.03943  0.04882  0.02335  114 ASN A C   
1477 O  O   . ASN A 91  ? 0.25583 0.18725 0.29511 0.02849  0.05749  0.01146  114 ASN A O   
1478 C  CB  . ASN A 91  ? 0.24338 0.17774 0.31033 0.05574  0.04625  0.03067  114 ASN A CB  
1479 C  CG  . ASN A 91  ? 0.28075 0.21778 0.32789 0.05672  0.04849  0.04056  114 ASN A CG  
1480 O  OD1 . ASN A 91  ? 0.32246 0.19292 0.33811 0.02441  0.03257  0.01706  114 ASN A OD1 
1481 N  ND2 . ASN A 91  ? 0.32249 0.27799 0.33829 0.07214  0.04816  0.06688  114 ASN A ND2 
1488 N  N   . GLY A 92  ? 0.21198 0.17415 0.27497 0.03978  0.06344  0.03591  115 GLY A N   
1489 C  CA  . GLY A 92  ? 0.18988 0.18593 0.27453 0.02513  0.06128  0.02645  115 GLY A CA  
1490 C  C   . GLY A 92  ? 0.16971 0.17731 0.26355 -0.00538 0.05300  0.02350  115 GLY A C   
1491 O  O   . GLY A 92  ? 0.18467 0.16029 0.27327 -0.01149 0.04731  0.02847  115 GLY A O   
1495 N  N   . THR A 93  ? 0.17704 0.15763 0.23897 0.01174  0.04669  0.01662  116 THR A N   
1496 C  CA  . THR A 93  ? 0.15843 0.15152 0.22613 -0.00259 0.04494  0.00641  116 THR A CA  
1497 C  C   . THR A 93  ? 0.15501 0.16415 0.22261 0.02801  0.02990  -0.00184 116 THR A C   
1498 O  O   . THR A 93  ? 0.16140 0.17849 0.22404 0.02428  0.02029  0.00309  116 THR A O   
1499 C  CB  . THR A 93  ? 0.14606 0.15065 0.22470 0.00601  0.03617  -0.00190 116 THR A CB  
1500 O  OG1 . THR A 93  ? 0.15944 0.14085 0.22963 0.01785  0.04102  -0.01479 116 THR A OG1 
1501 C  CG2 . THR A 93  ? 0.18010 0.18115 0.23081 -0.00615 0.03909  -0.02212 116 THR A CG2 
1509 N  N   . MET A 94  ? 0.16086 0.13799 0.21350 0.01285  0.02585  0.00211  117 MET A N   
1510 C  CA  . MET A 94  ? 0.18676 0.13344 0.20887 0.01964  0.03971  -0.00533 117 MET A CA  
1511 C  C   . MET A 94  ? 0.17662 0.14551 0.20560 0.00411  0.03186  -0.00777 117 MET A C   
1512 O  O   . MET A 94  ? 0.19669 0.14643 0.19918 -0.00060 0.03572  -0.01829 117 MET A O   
1513 C  CB  . MET A 94  ? 0.18690 0.15647 0.20464 0.01131  0.03152  -0.00547 117 MET A CB  
1514 C  CG  . MET A 94  ? 0.20676 0.16489 0.20304 0.02137  0.03391  0.00360  117 MET A CG  
1515 S  SD  . MET A 94  ? 0.21728 0.17422 0.19708 0.02649  0.02384  0.01465  117 MET A SD  
1516 C  CE  . MET A 94  ? 0.25530 0.16411 0.19997 0.01244  0.02028  0.00115  117 MET A CE  
1526 N  N   . SER A 95  ? 0.16631 0.14834 0.19908 0.00795  0.03005  -0.00222 118 SER A N   
1527 C  CA  . SER A 95  ? 0.16468 0.15217 0.18941 -0.00608 0.02761  -0.00574 118 SER A CA  
1528 C  C   . SER A 95  ? 0.15180 0.13543 0.17711 -0.00647 0.01929  -0.01809 118 SER A C   
1529 O  O   . SER A 95  ? 0.17118 0.12444 0.16789 -0.00591 0.02131  -0.01018 118 SER A O   
1530 C  CB  . SER A 95  ? 0.16373 0.16226 0.20086 -0.00123 0.03061  -0.00576 118 SER A CB  
1531 O  OG  . SER A 95  ? 0.15733 0.16387 0.21236 -0.00609 0.01961  -0.00941 118 SER A OG  
1537 N  N   . LEU A 96  ? 0.14782 0.14511 0.17570 0.00512  0.01812  -0.00250 119 LEU A N   
1538 C  CA  . LEU A 96  ? 0.15211 0.15828 0.17425 -0.00136 0.02199  -0.01245 119 LEU A CA  
1539 C  C   . LEU A 96  ? 0.14988 0.13163 0.17433 0.00260  0.01527  -0.01083 119 LEU A C   
1540 O  O   . LEU A 96  ? 0.14196 0.13790 0.16836 -0.00265 0.02370  -0.00796 119 LEU A O   
1541 C  CB  . LEU A 96  ? 0.16659 0.15628 0.17460 -0.00808 0.01753  -0.02418 119 LEU A CB  
1542 C  CG  . LEU A 96  ? 0.15551 0.18131 0.18486 0.00099  0.01336  -0.01761 119 LEU A CG  
1543 C  CD1 . LEU A 96  ? 0.18353 0.21388 0.19032 -0.00616 0.00781  -0.02820 119 LEU A CD1 
1544 C  CD2 . LEU A 96  ? 0.17846 0.18558 0.19544 -0.00767 0.01251  0.00096  119 LEU A CD2 
1556 N  N   . ALA A 97  ? 0.16201 0.14057 0.17120 -0.00526 0.01507  -0.00401 120 ALA A N   
1557 C  CA  . ALA A 97  ? 0.15533 0.12747 0.17906 -0.02694 0.00556  0.00543  120 ALA A CA  
1558 C  C   . ALA A 97  ? 0.15906 0.12186 0.17435 -0.02671 0.01217  -0.00201 120 ALA A C   
1559 O  O   . ALA A 97  ? 0.16568 0.13301 0.17417 -0.01499 0.00639  -0.01069 120 ALA A O   
1560 C  CB  . ALA A 97  ? 0.19321 0.15680 0.19188 -0.03338 0.01282  0.00399  120 ALA A CB  
1566 N  N   . GLU A 98  ? 0.14846 0.14180 0.17193 -0.00911 0.00935  0.00225  121 GLU A N   
1567 C  CA  . GLU A 98  ? 0.13395 0.14968 0.18216 -0.00079 0.00439  0.00621  121 GLU A CA  
1568 C  C   . GLU A 98  ? 0.13701 0.12836 0.17093 0.00831  0.00914  -0.00052 121 GLU A C   
1569 O  O   . GLU A 98  ? 0.16361 0.13832 0.16507 0.00786  0.00870  0.00866  121 GLU A O   
1570 C  CB  . GLU A 98  ? 0.12328 0.20579 0.21313 0.02444  0.00996  -0.00165 121 GLU A CB  
1571 C  CG  . GLU A 98  ? 0.13710 0.26852 0.25136 0.01584  -0.00898 -0.00959 121 GLU A CG  
1572 C  CD  . GLU A 98  ? 0.15851 0.30953 0.29493 0.01051  -0.01307 -0.01581 121 GLU A CD  
1573 O  OE1 . GLU A 98  ? 0.17084 0.22417 0.30319 0.03238  -0.00972 -0.00341 121 GLU A OE1 
1574 O  OE2 . GLU A 98  ? 0.19357 0.40351 0.32633 0.02534  -0.01819 -0.03349 121 GLU A OE2 
1581 N  N   . LEU A 99  ? 0.13195 0.11949 0.15886 -0.00363 0.00941  0.00048  122 LEU A N   
1582 C  CA  . LEU A 99  ? 0.12265 0.12284 0.16398 -0.00325 0.00263  -0.00196 122 LEU A CA  
1583 C  C   . LEU A 99  ? 0.12111 0.11717 0.14928 -0.01132 -0.00083 -0.00482 122 LEU A C   
1584 O  O   . LEU A 99  ? 0.14429 0.11123 0.14046 0.00491  0.01616  -0.00535 122 LEU A O   
1585 C  CB  . LEU A 99  ? 0.14173 0.12286 0.15839 -0.00642 0.02123  0.00316  122 LEU A CB  
1586 C  CG  . LEU A 99  ? 0.14712 0.13020 0.18509 -0.00315 0.02980  -0.01282 122 LEU A CG  
1587 C  CD1 . LEU A 99  ? 0.18729 0.12843 0.18683 -0.01118 0.03730  -0.03350 122 LEU A CD1 
1588 C  CD2 . LEU A 99  ? 0.16735 0.12557 0.20239 0.00503  0.04105  -0.00935 122 LEU A CD2 
1600 N  N   . SER A 100 ? 0.14135 0.11561 0.14307 0.00184  0.02138  0.01197  123 SER A N   
1601 C  CA  . SER A 100 ? 0.12070 0.10880 0.14929 0.00659  0.01472  0.00410  123 SER A CA  
1602 C  C   . SER A 100 ? 0.13472 0.10985 0.15157 -0.00098 0.00851  -0.00016 123 SER A C   
1603 O  O   . SER A 100 ? 0.14933 0.11812 0.15387 -0.00150 0.01217  -0.00733 123 SER A O   
1604 C  CB  . SER A 100 ? 0.15349 0.12034 0.15443 -0.00319 0.02166  0.00759  123 SER A CB  
1605 O  OG  . SER A 100 ? 0.16964 0.13736 0.15689 -0.00646 0.01583  -0.00019 123 SER A OG  
1611 N  N   . ALA A 101 ? 0.15197 0.12033 0.15475 -0.00645 0.01494  -0.00021 124 ALA A N   
1612 C  CA  . ALA A 101 ? 0.15924 0.14169 0.15948 -0.01372 0.00267  -0.00520 124 ALA A CA  
1613 C  C   . ALA A 101 ? 0.15251 0.12997 0.15668 -0.02448 -0.00624 -0.01483 124 ALA A C   
1614 O  O   . ALA A 101 ? 0.15035 0.14978 0.16328 -0.00672 -0.00056 -0.02326 124 ALA A O   
1615 C  CB  . ALA A 101 ? 0.17203 0.15885 0.16384 -0.02151 0.01297  -0.01785 124 ALA A CB  
1621 N  N   . ALA A 102 ? 0.15752 0.11942 0.14825 -0.01757 -0.00353 -0.02176 125 ALA A N   
1622 C  CA  . ALA A 102 ? 0.15668 0.12705 0.14016 -0.01185 0.00270  0.00150  125 ALA A CA  
1623 C  C   . ALA A 102 ? 0.15188 0.11528 0.13971 -0.01293 -0.00452 0.00405  125 ALA A C   
1624 O  O   . ALA A 102 ? 0.17417 0.12383 0.13228 -0.01008 -0.01394 0.00285  125 ALA A O   
1625 C  CB  . ALA A 102 ? 0.17399 0.13292 0.14817 0.00717  -0.00303 0.00835  125 ALA A CB  
1631 N  N   . ALA A 103 ? 0.13627 0.10912 0.13427 0.00507  -0.00826 -0.00197 126 ALA A N   
1632 C  CA  . ALA A 103 ? 0.14182 0.11111 0.13007 -0.00853 -0.00799 -0.00278 126 ALA A CA  
1633 C  C   . ALA A 103 ? 0.14238 0.11160 0.12979 -0.01796 -0.00199 0.00122  126 ALA A C   
1634 O  O   . ALA A 103 ? 0.16134 0.12072 0.12856 0.00093  0.00463  0.00090  126 ALA A O   
1635 C  CB  . ALA A 103 ? 0.14514 0.12759 0.12530 -0.00848 -0.00871 0.00354  126 ALA A CB  
1641 N  N   . LEU A 104 ? 0.15549 0.10204 0.13296 -0.00837 0.00297  -0.00358 127 LEU A N   
1642 C  CA  . LEU A 104 ? 0.16260 0.10162 0.12965 -0.00464 -0.00837 -0.00662 127 LEU A CA  
1643 C  C   . LEU A 104 ? 0.16087 0.10995 0.12690 -0.00615 0.00132  -0.00154 127 LEU A C   
1644 O  O   . LEU A 104 ? 0.19342 0.13539 0.12473 0.02036  0.00029  -0.01248 127 LEU A O   
1645 C  CB  . LEU A 104 ? 0.15336 0.11132 0.13396 0.00253  -0.00978 -0.00930 127 LEU A CB  
1646 C  CG  . LEU A 104 ? 0.14198 0.12485 0.14010 0.00209  0.00266  -0.00538 127 LEU A CG  
1647 C  CD1 . LEU A 104 ? 0.17883 0.13701 0.14313 -0.01286 -0.01141 0.00036  127 LEU A CD1 
1648 C  CD2 . LEU A 104 ? 0.15873 0.17213 0.14598 0.01162  0.00509  -0.01039 127 LEU A CD2 
1660 N  N   . GLN A 105 ? 0.16597 0.13135 0.13740 0.00650  -0.01544 -0.00811 128 GLN A N   
1661 C  CA  . GLN A 105 ? 0.18255 0.13783 0.14859 -0.01725 -0.02018 -0.00867 128 GLN A CA  
1662 C  C   . GLN A 105 ? 0.17016 0.15030 0.14867 -0.01976 -0.01687 -0.02136 128 GLN A C   
1663 O  O   . GLN A 105 ? 0.20467 0.14952 0.15455 -0.00608 -0.02814 -0.02225 128 GLN A O   
1664 C  CB  . GLN A 105 ? 0.18078 0.13211 0.16090 -0.01686 -0.02584 -0.02035 128 GLN A CB  
1665 C  CG  . GLN A 105 ? 0.17371 0.13657 0.17642 -0.02484 -0.01504 -0.01318 128 GLN A CG  
1666 C  CD  . GLN A 105 ? 0.17099 0.17824 0.20395 0.00637  -0.00178 -0.00425 128 GLN A CD  
1667 O  OE1 . GLN A 105 ? 0.21128 0.19984 0.22952 0.01986  0.00861  0.01893  128 GLN A OE1 
1668 N  NE2 . GLN A 105 ? 0.14900 0.17619 0.20951 -0.01738 0.00833  -0.00019 128 GLN A NE2 
1677 N  N   . TYR A 106 ? 0.17739 0.14079 0.14512 -0.01576 -0.02092 -0.00396 129 TYR A N   
1678 C  CA  . TYR A 106 ? 0.19223 0.13745 0.15703 -0.00893 -0.02993 0.00580  129 TYR A CA  
1679 C  C   . TYR A 106 ? 0.18152 0.14332 0.15138 -0.02333 -0.02582 -0.00017 129 TYR A C   
1680 O  O   . TYR A 106 ? 0.19287 0.17940 0.15975 -0.01915 -0.03618 0.02752  129 TYR A O   
1681 C  CB  . TYR A 106 ? 0.19994 0.15220 0.18284 -0.01354 -0.03545 0.00291  129 TYR A CB  
1682 C  CG  . TYR A 106 ? 0.19290 0.17448 0.21005 -0.00056 -0.04986 -0.01694 129 TYR A CG  
1683 C  CD1 . TYR A 106 ? 0.18545 0.23872 0.22682 0.02218  -0.07064 -0.03240 129 TYR A CD1 
1684 C  CD2 . TYR A 106 ? 0.19044 0.17901 0.22693 0.00199  -0.03669 -0.01526 129 TYR A CD2 
1685 C  CE1 . TYR A 106 ? 0.19305 0.26268 0.24630 0.02338  -0.06431 -0.03766 129 TYR A CE1 
1686 C  CE2 . TYR A 106 ? 0.21197 0.20764 0.25149 -0.00382 -0.03305 -0.01736 129 TYR A CE2 
1687 C  CZ  . TYR A 106 ? 0.19561 0.26492 0.26627 -0.00698 -0.04499 -0.03580 129 TYR A CZ  
1688 O  OH  . TYR A 106 ? 0.22327 0.31448 0.29276 -0.03640 -0.04557 -0.05247 129 TYR A OH  
1698 N  N   . SER A 107 ? 0.15990 0.13134 0.13862 0.00556  -0.00677 0.00853  130 SER A N   
1699 C  CA  . SER A 107 ? 0.15919 0.12789 0.13105 -0.00349 -0.00191 0.00625  130 SER A CA  
1700 C  C   . SER A 107 ? 0.15705 0.11729 0.13175 -0.00640 -0.00076 0.01030  130 SER A C   
1701 O  O   . SER A 107 ? 0.17764 0.12199 0.14760 0.00198  0.00885  0.00728  130 SER A O   
1702 C  CB  . SER A 107 ? 0.16156 0.13945 0.12574 -0.01184 -0.00935 0.00325  130 SER A CB  
1703 O  OG  . SER A 107 ? 0.15824 0.12856 0.12685 -0.00436 0.00258  -0.00773 130 SER A OG  
1709 N  N   . ASP A 108 ? 0.14934 0.12250 0.13524 0.00056  -0.00530 -0.00245 131 ASP A N   
1710 C  CA  . ASP A 108 ? 0.14910 0.11006 0.14053 -0.00140 -0.01189 -0.00047 131 ASP A CA  
1711 C  C   . ASP A 108 ? 0.13108 0.12404 0.14215 0.00206  -0.01529 0.00573  131 ASP A C   
1712 O  O   . ASP A 108 ? 0.15642 0.13714 0.14819 -0.00422 -0.02398 0.02365  131 ASP A O   
1713 C  CB  . ASP A 108 ? 0.12945 0.12447 0.14695 -0.00952 -0.02715 -0.00223 131 ASP A CB  
1714 C  CG  . ASP A 108 ? 0.13845 0.13874 0.14609 0.00509  -0.02966 0.00328  131 ASP A CG  
1715 O  OD1 . ASP A 108 ? 0.17113 0.11900 0.14892 0.00448  -0.02898 -0.00243 131 ASP A OD1 
1716 O  OD2 . ASP A 108 ? 0.17899 0.14036 0.14945 0.00921  -0.04159 -0.01251 131 ASP A OD2 
1721 N  N   . ASN A 109 ? 0.13584 0.11960 0.13165 -0.01101 -0.01132 0.00844  132 ASN A N   
1722 C  CA  . ASN A 109 ? 0.14352 0.12296 0.12891 -0.00592 -0.00044 0.01504  132 ASN A CA  
1723 C  C   . ASN A 109 ? 0.15164 0.11446 0.12181 -0.00607 -0.00751 0.00364  132 ASN A C   
1724 O  O   . ASN A 109 ? 0.14871 0.12410 0.11381 -0.00151 -0.00749 0.00741  132 ASN A O   
1725 C  CB  . ASN A 109 ? 0.16160 0.13191 0.13576 -0.01322 -0.00232 0.00690  132 ASN A CB  
1726 C  CG  . ASN A 109 ? 0.18721 0.18943 0.14515 0.00995  -0.00356 0.02331  132 ASN A CG  
1727 O  OD1 . ASN A 109 ? 0.20043 0.17563 0.16645 0.02828  0.01594  0.00873  132 ASN A OD1 
1728 N  ND2 . ASN A 109 ? 0.22619 0.25691 0.15288 0.02733  0.02425  0.04272  132 ASN A ND2 
1735 N  N   . VAL A 110 ? 0.15342 0.11538 0.12091 0.00421  -0.00878 0.01687  133 VAL A N   
1736 C  CA  . VAL A 110 ? 0.14526 0.11095 0.13364 0.00633  -0.00865 0.00195  133 VAL A CA  
1737 C  C   . VAL A 110 ? 0.14312 0.10678 0.12371 0.00787  -0.00375 0.00107  133 VAL A C   
1738 O  O   . VAL A 110 ? 0.14522 0.11393 0.12640 -0.00175 -0.00375 -0.00119 133 VAL A O   
1739 C  CB  . VAL A 110 ? 0.15853 0.11687 0.14522 0.01390  -0.00150 0.01391  133 VAL A CB  
1740 C  CG1 . VAL A 110 ? 0.15409 0.13317 0.14870 0.00583  -0.01054 0.00017  133 VAL A CG1 
1741 C  CG2 . VAL A 110 ? 0.20487 0.12469 0.15392 0.01884  -0.00867 0.01717  133 VAL A CG2 
1751 N  N   . ALA A 111 ? 0.13811 0.10668 0.12912 -0.00432 -0.01431 0.00473  134 ALA A N   
1752 C  CA  . ALA A 111 ? 0.13543 0.12633 0.12593 -0.00677 0.00211  0.00774  134 ALA A CA  
1753 C  C   . ALA A 111 ? 0.13927 0.11022 0.12087 -0.01382 -0.00178 -0.00035 134 ALA A C   
1754 O  O   . ALA A 111 ? 0.14738 0.12265 0.11160 0.00116  0.00156  -0.00165 134 ALA A O   
1755 C  CB  . ALA A 111 ? 0.14414 0.12333 0.13135 -0.00390 -0.00132 0.00452  134 ALA A CB  
1761 N  N   . MET A 112 ? 0.12745 0.11576 0.12234 0.00589  -0.00671 -0.00082 135 MET A N   
1762 C  CA  . MET A 112 ? 0.13839 0.11358 0.12538 -0.00465 0.00257  -0.00246 135 MET A CA  
1763 C  C   . MET A 112 ? 0.12564 0.12532 0.11413 -0.01045 0.00065  -0.01301 135 MET A C   
1764 O  O   . MET A 112 ? 0.14093 0.12548 0.10883 0.01060  0.00622  -0.01262 135 MET A O   
1765 C  CB  . MET A 112 ? 0.15885 0.10485 0.12886 -0.00921 0.00658  -0.00615 135 MET A CB  
1766 C  CG  . MET A 112 ? 0.13988 0.11292 0.12580 -0.00110 0.00827  -0.01263 135 MET A CG  
1767 S  SD  . MET A 112 ? 0.15000 0.10988 0.11672 0.00184  -0.00133 -0.00811 135 MET A SD  
1768 C  CE  . MET A 112 ? 0.14511 0.12816 0.14191 -0.00021 -0.00931 0.00823  135 MET A CE  
1778 N  N   . ASN A 113 ? 0.14534 0.10144 0.11084 0.00134  0.00829  -0.00336 136 ASN A N   
1779 C  CA  . ASN A 113 ? 0.14105 0.11592 0.11631 0.01418  0.00273  -0.00841 136 ASN A CA  
1780 C  C   . ASN A 113 ? 0.13893 0.12457 0.11434 0.00863  0.00247  0.00125  136 ASN A C   
1781 O  O   . ASN A 113 ? 0.13880 0.13920 0.10462 0.00498  -0.00367 -0.00068 136 ASN A O   
1782 C  CB  . ASN A 113 ? 0.14100 0.11392 0.11880 0.01157  0.00460  -0.01384 136 ASN A CB  
1783 C  CG  . ASN A 113 ? 0.13680 0.12199 0.12888 0.00649  -0.00011 -0.01385 136 ASN A CG  
1784 O  OD1 . ASN A 113 ? 0.13678 0.12001 0.12775 0.00490  0.00361  -0.00429 136 ASN A OD1 
1785 N  ND2 . ASN A 113 ? 0.16166 0.10465 0.13318 0.00714  0.01514  -0.01048 136 ASN A ND2 
1792 N  N   . LYS A 114 ? 0.13024 0.13505 0.11112 0.01402  0.00962  0.00005  137 LYS A N   
1793 C  CA  . LYS A 114 ? 0.13738 0.13232 0.11791 0.00444  0.01395  0.00044  137 LYS A CA  
1794 C  C   . LYS A 114 ? 0.14433 0.13782 0.12267 0.00596  0.01619  0.00541  137 LYS A C   
1795 O  O   . LYS A 114 ? 0.15700 0.15286 0.11195 0.00796  0.00173  0.00635  137 LYS A O   
1796 C  CB  . LYS A 114 ? 0.13038 0.13091 0.13100 0.00015  0.02343  0.00799  137 LYS A CB  
1797 C  CG  . LYS A 114 ? 0.11527 0.14228 0.13895 0.00268  0.00763  -0.00735 137 LYS A CG  
1798 C  CD  . LYS A 114 ? 0.13041 0.13780 0.13640 0.01158  0.01244  -0.01241 137 LYS A CD  
1799 C  CE  . LYS A 114 ? 0.16726 0.13453 0.14794 0.00360  -0.00083 -0.01600 137 LYS A CE  
1800 N  NZ  . LYS A 114 ? 0.21192 0.13257 0.15254 0.00964  0.00313  -0.01244 137 LYS A NZ  
1814 N  N   . LEU A 115 ? 0.13978 0.12677 0.11785 0.00707  0.00349  0.00787  138 LEU A N   
1815 C  CA  . LEU A 115 ? 0.13792 0.14189 0.12417 0.00790  0.00279  0.00316  138 LEU A CA  
1816 C  C   . LEU A 115 ? 0.14229 0.12603 0.11338 0.01593  0.00116  0.00613  138 LEU A C   
1817 O  O   . LEU A 115 ? 0.16876 0.14725 0.11719 -0.00033 -0.00100 0.00829  138 LEU A O   
1818 C  CB  . LEU A 115 ? 0.15560 0.13380 0.13717 -0.00210 -0.00118 0.01696  138 LEU A CB  
1819 C  CG  . LEU A 115 ? 0.16661 0.13506 0.16118 -0.01349 0.00096  0.00875  138 LEU A CG  
1820 C  CD1 . LEU A 115 ? 0.18147 0.14931 0.15419 -0.04177 -0.00969 0.00737  138 LEU A CD1 
1821 C  CD2 . LEU A 115 ? 0.16369 0.19947 0.17768 -0.01933 0.01909  0.00437  138 LEU A CD2 
1833 N  N   . ILE A 116 ? 0.13875 0.14102 0.11196 0.00926  0.00853  0.00221  139 ILE A N   
1834 C  CA  . ILE A 116 ? 0.14129 0.14658 0.11472 0.01437  -0.00787 0.00662  139 ILE A CA  
1835 C  C   . ILE A 116 ? 0.15250 0.14566 0.11896 0.01839  -0.00883 -0.00468 139 ILE A C   
1836 O  O   . ILE A 116 ? 0.16557 0.16414 0.10872 0.01239  -0.01742 -0.00517 139 ILE A O   
1837 C  CB  . ILE A 116 ? 0.13400 0.13949 0.11473 0.01124  -0.00562 -0.00382 139 ILE A CB  
1838 C  CG1 . ILE A 116 ? 0.13382 0.14054 0.11586 0.00674  -0.00883 -0.01005 139 ILE A CG1 
1839 C  CG2 . ILE A 116 ? 0.12570 0.18107 0.12514 -0.00329 -0.00989 -0.00478 139 ILE A CG2 
1840 C  CD1 . ILE A 116 ? 0.14514 0.13780 0.11853 0.00518  -0.00818 -0.00509 139 ILE A CD1 
1852 N  N   . ALA A 117 ? 0.15385 0.15721 0.12008 0.01914  -0.00457 -0.01495 140 ALA A N   
1853 C  CA  . ALA A 117 ? 0.16543 0.14759 0.11793 0.01900  -0.00858 -0.01899 140 ALA A CA  
1854 C  C   . ALA A 117 ? 0.17203 0.14316 0.11824 0.01276  0.00485  -0.01440 140 ALA A C   
1855 O  O   . ALA A 117 ? 0.19730 0.17711 0.11873 0.00407  -0.00544 -0.01515 140 ALA A O   
1856 C  CB  . ALA A 117 ? 0.21042 0.15657 0.13297 0.01285  -0.00723 -0.03019 140 ALA A CB  
1862 N  N   . HIS A 118 ? 0.16030 0.17146 0.11899 0.01325  0.00580  -0.01090 141 HIS A N   
1863 C  CA  . HIS A 118 ? 0.17814 0.17922 0.14601 0.00550  0.01911  -0.00235 141 HIS A CA  
1864 C  C   . HIS A 118 ? 0.21248 0.21668 0.13489 0.00586  0.03698  0.01219  141 HIS A C   
1865 O  O   . HIS A 118 ? 0.22319 0.25860 0.13305 0.00694  0.02514  0.01218  141 HIS A O   
1866 C  CB  . HIS A 118 ? 0.22190 0.18305 0.16697 -0.01290 0.02158  0.00666  141 HIS A CB  
1867 C  CG  . HIS A 118 ? 0.24936 0.21682 0.18959 -0.01673 0.03004  0.00633  141 HIS A CG  
1868 N  ND1 . HIS A 118 ? 0.25779 0.22441 0.19611 0.00989  0.04720  -0.00464 141 HIS A ND1 
1869 C  CD2 . HIS A 118 ? 0.28981 0.22318 0.19849 -0.02571 0.04673  0.00627  141 HIS A CD2 
1870 C  CE1 . HIS A 118 ? 0.28820 0.22295 0.20306 -0.00683 0.05421  0.02485  141 HIS A CE1 
1871 N  NE2 . HIS A 118 ? 0.31273 0.24776 0.20418 -0.00644 0.05461  0.01369  141 HIS A NE2 
1879 N  N   . VAL A 119 ? 0.19390 0.17947 0.13400 0.01649  0.00989  0.00977  142 VAL A N   
1880 C  CA  . VAL A 119 ? 0.21839 0.19302 0.14072 0.02594  0.01793  0.02154  142 VAL A CA  
1881 C  C   . VAL A 119 ? 0.20257 0.20290 0.12153 0.05071  0.02423  0.03178  142 VAL A C   
1882 O  O   . VAL A 119 ? 0.22170 0.23134 0.12632 0.05371  0.01507  0.03573  142 VAL A O   
1883 C  CB  . VAL A 119 ? 0.20917 0.18525 0.15335 0.01458  0.02958  0.00594  142 VAL A CB  
1884 C  CG1 . VAL A 119 ? 0.22032 0.18194 0.17598 -0.03379 0.04637  0.00512  142 VAL A CG1 
1885 C  CG2 . VAL A 119 ? 0.20434 0.17556 0.13797 0.03155  0.00917  -0.01519 142 VAL A CG2 
1896 N  N   . GLY A 120 ? 0.18620 0.20318 0.11615 0.03493  -0.01198 0.01134  143 GLY A N   
1897 C  CA  . GLY A 120 ? 0.17229 0.23089 0.11945 0.02150  -0.01761 -0.01632 143 GLY A CA  
1898 C  C   . GLY A 120 ? 0.15393 0.23308 0.12109 -0.00830 -0.01446 -0.01584 143 GLY A C   
1899 O  O   . GLY A 120 ? 0.18309 0.29081 0.12576 -0.02952 -0.01145 -0.02464 143 GLY A O   
1903 N  N   . GLY A 121 ? 0.16305 0.15392 0.10808 0.01108  -0.01490 -0.02328 144 GLY A N   
1904 C  CA  . GLY A 121 ? 0.16245 0.14495 0.10702 0.01322  -0.01007 -0.01302 144 GLY A CA  
1905 C  C   . GLY A 121 ? 0.14828 0.12344 0.11109 0.00482  -0.01357 -0.01938 144 GLY A C   
1906 O  O   . GLY A 121 ? 0.15895 0.12340 0.11353 -0.00080 -0.00543 -0.01171 144 GLY A O   
1910 N  N   . PRO A 122 ? 0.15267 0.10599 0.11206 -0.00871 -0.00016 -0.00069 145 PRO A N   
1911 C  CA  . PRO A 122 ? 0.15318 0.11900 0.10870 -0.00923 0.00235  -0.00206 145 PRO A CA  
1912 C  C   . PRO A 122 ? 0.15201 0.11757 0.11583 0.00902  -0.00091 0.00502  145 PRO A C   
1913 O  O   . PRO A 122 ? 0.18491 0.10344 0.10754 -0.00597 0.01017  -0.00852 145 PRO A O   
1914 C  CB  . PRO A 122 ? 0.15118 0.12143 0.12229 -0.00554 -0.00158 -0.00206 145 PRO A CB  
1915 C  CG  . PRO A 122 ? 0.16138 0.11704 0.12307 0.00120  0.01028  -0.00582 145 PRO A CG  
1916 C  CD  . PRO A 122 ? 0.15485 0.11422 0.11953 0.01333  -0.01104 -0.00151 145 PRO A CD  
1924 N  N   . ALA A 123 ? 0.14863 0.11521 0.12452 -0.00823 -0.00687 -0.00356 146 ALA A N   
1925 C  CA  . ALA A 123 ? 0.14970 0.11562 0.12499 -0.00380 -0.00031 -0.00986 146 ALA A CA  
1926 C  C   . ALA A 123 ? 0.14630 0.12318 0.11946 -0.00050 -0.00243 -0.01491 146 ALA A C   
1927 O  O   . ALA A 123 ? 0.14875 0.11633 0.12471 0.00418  -0.01054 0.00389  146 ALA A O   
1928 C  CB  . ALA A 123 ? 0.15199 0.13361 0.13206 -0.00793 -0.00249 0.01148  146 ALA A CB  
1934 N  N   . SER A 124 ? 0.14261 0.11555 0.11485 -0.00554 0.00620  -0.01333 147 SER A N   
1935 C  CA  A SER A 124 ? 0.15424 0.12792 0.12009 0.00226  0.01769  -0.01005 147 SER A CA  
1936 C  CA  B SER A 124 ? 0.15586 0.11710 0.11701 -0.00876 0.00533  -0.01585 147 SER A CA  
1937 C  C   . SER A 124 ? 0.16541 0.11546 0.11172 -0.01612 0.00493  -0.00785 147 SER A C   
1938 O  O   . SER A 124 ? 0.16010 0.13025 0.11151 -0.00556 0.00131  -0.00615 147 SER A O   
1939 C  CB  A SER A 124 ? 0.15437 0.15130 0.13401 -0.00650 0.02156  -0.00401 147 SER A CB  
1940 C  CB  B SER A 124 ? 0.15507 0.11522 0.12337 -0.01417 0.00053  -0.02582 147 SER A CB  
1941 O  OG  A SER A 124 ? 0.19422 0.15600 0.15066 0.00193  0.03990  0.00275  147 SER A OG  
1942 O  OG  B SER A 124 ? 0.16237 0.10900 0.13077 -0.00580 -0.00218 -0.03692 147 SER A OG  
1953 N  N   . VAL A 125 ? 0.15727 0.11680 0.11101 -0.00398 -0.00113 -0.00053 148 VAL A N   
1954 C  CA  . VAL A 125 ? 0.13857 0.12062 0.11139 -0.01091 0.00007  0.00241  148 VAL A CA  
1955 C  C   . VAL A 125 ? 0.13597 0.11206 0.10012 -0.00701 -0.00379 0.00373  148 VAL A C   
1956 O  O   . VAL A 125 ? 0.15497 0.11037 0.11024 -0.00913 -0.01053 -0.00270 148 VAL A O   
1957 C  CB  . VAL A 125 ? 0.13549 0.12845 0.11128 0.01498  -0.00774 -0.00257 148 VAL A CB  
1958 C  CG1 . VAL A 125 ? 0.16186 0.11877 0.11239 -0.00001 -0.01330 -0.01163 148 VAL A CG1 
1959 C  CG2 . VAL A 125 ? 0.14561 0.14657 0.11256 -0.00307 -0.01458 0.00110  148 VAL A CG2 
1969 N  N   . THR A 126 ? 0.12817 0.11112 0.10460 -0.00394 -0.00680 0.00009  149 THR A N   
1970 C  CA  . THR A 126 ? 0.14070 0.11257 0.10419 -0.00447 -0.00115 -0.01130 149 THR A CA  
1971 C  C   . THR A 126 ? 0.14130 0.11646 0.10123 -0.00408 -0.00656 -0.00118 149 THR A C   
1972 O  O   . THR A 126 ? 0.16299 0.11025 0.10919 0.00070  0.00189  0.00040  149 THR A O   
1973 C  CB  . THR A 126 ? 0.15385 0.12723 0.10839 -0.00690 -0.00193 -0.00665 149 THR A CB  
1974 O  OG1 . THR A 126 ? 0.16257 0.12239 0.10609 -0.00512 0.00368  0.00202  149 THR A OG1 
1975 C  CG2 . THR A 126 ? 0.14043 0.11446 0.11697 -0.00212 0.00255  -0.00898 149 THR A CG2 
1983 N  N   . ALA A 127 ? 0.15252 0.10981 0.10136 -0.00495 -0.00020 -0.00299 150 ALA A N   
1984 C  CA  . ALA A 127 ? 0.14830 0.12032 0.10509 0.00100  -0.00474 0.00082  150 ALA A CA  
1985 C  C   . ALA A 127 ? 0.15744 0.11998 0.10049 0.00355  -0.01026 -0.00113 150 ALA A C   
1986 O  O   . ALA A 127 ? 0.16698 0.12136 0.09929 0.01048  -0.01189 -0.00351 150 ALA A O   
1987 C  CB  . ALA A 127 ? 0.17263 0.13205 0.09849 0.00025  -0.00347 0.00176  150 ALA A CB  
1993 N  N   . PHE A 128 ? 0.14838 0.11556 0.11047 0.00419  -0.00397 0.00958  151 PHE A N   
1994 C  CA  . PHE A 128 ? 0.14494 0.12591 0.11256 0.00128  0.00882  0.00076  151 PHE A CA  
1995 C  C   . PHE A 128 ? 0.15397 0.11129 0.11573 -0.00871 -0.00635 0.00658  151 PHE A C   
1996 O  O   . PHE A 128 ? 0.16541 0.10973 0.11375 0.00054  -0.00055 0.00672  151 PHE A O   
1997 C  CB  . PHE A 128 ? 0.14491 0.11151 0.12929 0.00617  0.02352  0.00804  151 PHE A CB  
1998 C  CG  . PHE A 128 ? 0.15725 0.12967 0.15114 -0.01339 0.00746  0.00266  151 PHE A CG  
1999 C  CD1 . PHE A 128 ? 0.17838 0.15036 0.16995 -0.02271 0.02201  0.00028  151 PHE A CD1 
2000 C  CD2 . PHE A 128 ? 0.15428 0.14702 0.16114 0.00477  -0.00638 -0.00148 151 PHE A CD2 
2001 C  CE1 . PHE A 128 ? 0.16543 0.17982 0.18818 -0.01270 0.02301  -0.00257 151 PHE A CE1 
2002 C  CE2 . PHE A 128 ? 0.16903 0.18122 0.18245 0.00664  0.00291  -0.01383 151 PHE A CE2 
2003 C  CZ  . PHE A 128 ? 0.13929 0.16835 0.20181 0.00094  0.01246  -0.02251 151 PHE A CZ  
2013 N  N   . ALA A 129 ? 0.14643 0.11684 0.10741 -0.00715 -0.00049 0.00913  152 ALA A N   
2014 C  CA  . ALA A 129 ? 0.13949 0.11208 0.10265 -0.00325 -0.00095 0.00282  152 ALA A CA  
2015 C  C   . ALA A 129 ? 0.16840 0.11712 0.10562 -0.00422 0.00828  0.00076  152 ALA A C   
2016 O  O   . ALA A 129 ? 0.15778 0.11992 0.11266 0.01130  -0.00593 0.00217  152 ALA A O   
2017 C  CB  . ALA A 129 ? 0.15806 0.12593 0.10316 0.00088  -0.00563 0.00381  152 ALA A CB  
2023 N  N   . ARG A 130 ? 0.15165 0.11945 0.11171 -0.00698 -0.00002 -0.00872 153 ARG A N   
2024 C  CA  . ARG A 130 ? 0.15366 0.12876 0.12700 0.00669  -0.00326 0.00269  153 ARG A CA  
2025 C  C   . ARG A 130 ? 0.14603 0.12286 0.11461 -0.00837 0.00020  0.00909  153 ARG A C   
2026 O  O   . ARG A 130 ? 0.16649 0.14074 0.11657 0.01330  -0.01656 0.01694  153 ARG A O   
2027 C  CB  . ARG A 130 ? 0.14854 0.13333 0.12606 0.01353  0.00543  -0.00038 153 ARG A CB  
2028 C  CG  . ARG A 130 ? 0.16363 0.13857 0.13349 -0.00777 -0.01434 -0.00238 153 ARG A CG  
2029 C  CD  . ARG A 130 ? 0.17585 0.15894 0.12878 0.00043  -0.01303 0.00292  153 ARG A CD  
2030 N  NE  . ARG A 130 ? 0.16740 0.17857 0.13158 -0.00702 -0.01331 0.01020  153 ARG A NE  
2031 C  CZ  . ARG A 130 ? 0.17266 0.14908 0.12903 -0.02365 0.00488  0.00401  153 ARG A CZ  
2032 N  NH1 . ARG A 130 ? 0.17087 0.13421 0.11469 -0.01642 -0.01523 -0.00219 153 ARG A NH1 
2033 N  NH2 . ARG A 130 ? 0.17731 0.17342 0.13965 -0.01276 0.00365  -0.00806 153 ARG A NH2 
2047 N  N   A GLN A 131 ? 0.15585 0.13545 0.11975 -0.01218 0.00686  0.01551  154 GLN A N   
2048 N  N   B GLN A 131 ? 0.15252 0.12743 0.10872 0.00428  0.01439  0.02270  154 GLN A N   
2049 C  CA  A GLN A 131 ? 0.16797 0.14913 0.13211 -0.00986 0.00666  0.01250  154 GLN A CA  
2050 C  CA  B GLN A 131 ? 0.16234 0.12592 0.11988 0.01295  0.01066  0.01894  154 GLN A CA  
2051 C  C   A GLN A 131 ? 0.17312 0.13952 0.13161 -0.00355 0.00222  0.02011  154 GLN A C   
2052 C  C   B GLN A 131 ? 0.17349 0.12623 0.12282 0.01399  0.00148  0.03194  154 GLN A C   
2053 O  O   A GLN A 131 ? 0.19223 0.14686 0.13416 -0.00428 0.00602  0.01516  154 GLN A O   
2054 O  O   B GLN A 131 ? 0.20194 0.13522 0.12625 0.01621  0.00389  0.02759  154 GLN A O   
2055 C  CB  A GLN A 131 ? 0.19455 0.16770 0.14568 -0.01574 0.01273  0.00718  154 GLN A CB  
2056 C  CB  B GLN A 131 ? 0.19351 0.13034 0.13257 0.00883  0.01624  0.00843  154 GLN A CB  
2057 C  CG  A GLN A 131 ? 0.23095 0.18415 0.16121 -0.00773 0.01237  0.00084  154 GLN A CG  
2058 C  CG  B GLN A 131 ? 0.26417 0.13283 0.15414 -0.00365 0.01591  0.00448  154 GLN A CG  
2059 C  CD  A GLN A 131 ? 0.23403 0.20006 0.17449 -0.01702 0.03140  -0.01373 154 GLN A CD  
2060 C  CD  B GLN A 131 ? 0.29853 0.13308 0.17031 -0.01074 0.04003  0.00292  154 GLN A CD  
2061 O  OE1 A GLN A 131 ? 0.22363 0.19057 0.17958 -0.04063 0.03809  -0.00639 154 GLN A OE1 
2062 O  OE1 B GLN A 131 ? 0.30563 0.18122 0.18332 0.00265  0.02883  0.00872  154 GLN A OE1 
2063 N  NE2 A GLN A 131 ? 0.21376 0.20720 0.17616 -0.00920 0.04266  -0.01812 154 GLN A NE2 
2064 N  NE2 B GLN A 131 ? 0.33700 0.16791 0.18108 -0.03755 0.08300  -0.02789 154 GLN A NE2 
2081 N  N   . LEU A 132 ? 0.15913 0.12951 0.13368 -0.00455 -0.00141 0.02306  155 LEU A N   
2082 C  CA  . LEU A 132 ? 0.14818 0.12191 0.14157 -0.01192 -0.01274 0.02820  155 LEU A CA  
2083 C  C   . LEU A 132 ? 0.16974 0.11215 0.15285 -0.00105 -0.00660 0.01508  155 LEU A C   
2084 O  O   . LEU A 132 ? 0.20454 0.12606 0.19748 0.01036  -0.01392 0.00341  155 LEU A O   
2085 C  CB  . LEU A 132 ? 0.17856 0.14195 0.15335 -0.02783 -0.01990 0.00119  155 LEU A CB  
2086 C  CG  . LEU A 132 ? 0.19078 0.15849 0.16220 -0.00254 -0.02498 0.00275  155 LEU A CG  
2087 C  CD1 . LEU A 132 ? 0.22099 0.19217 0.16312 0.01830  -0.03821 -0.00764 155 LEU A CD1 
2088 C  CD2 . LEU A 132 ? 0.19009 0.18991 0.18053 -0.01772 -0.00556 0.01117  155 LEU A CD2 
2100 N  N   . GLY A 133 ? 0.16440 0.12021 0.13662 -0.00776 -0.01085 0.02047  156 GLY A N   
2101 C  CA  . GLY A 133 ? 0.17163 0.12684 0.13463 0.02340  -0.01081 0.02358  156 GLY A CA  
2102 C  C   . GLY A 133 ? 0.14207 0.12779 0.12619 0.01328  -0.00458 0.00986  156 GLY A C   
2103 O  O   . GLY A 133 ? 0.18938 0.15713 0.13565 0.04221  0.00224  0.01546  156 GLY A O   
2107 N  N   . ASP A 134 ? 0.17516 0.11254 0.11214 -0.00182 -0.00309 0.00269  157 ASP A N   
2108 C  CA  . ASP A 134 ? 0.14930 0.13232 0.10977 0.00533  -0.00625 0.00319  157 ASP A CA  
2109 C  C   . ASP A 134 ? 0.14704 0.12933 0.11461 0.00723  -0.01578 0.00308  157 ASP A C   
2110 O  O   . ASP A 134 ? 0.15737 0.13198 0.11829 -0.00254 -0.00458 -0.00055 157 ASP A O   
2111 C  CB  . ASP A 134 ? 0.13946 0.13412 0.10202 -0.01032 -0.00755 0.00281  157 ASP A CB  
2112 C  CG  . ASP A 134 ? 0.14201 0.13934 0.10251 -0.02094 -0.00049 -0.00349 157 ASP A CG  
2113 O  OD1 . ASP A 134 ? 0.14564 0.12636 0.10775 -0.01047 -0.00156 0.00417  157 ASP A OD1 
2114 O  OD2 . ASP A 134 ? 0.15077 0.14536 0.10768 -0.03044 -0.00253 0.00881  157 ASP A OD2 
2119 N  N   . GLU A 135 ? 0.15285 0.12318 0.12587 0.00576  -0.01221 -0.00791 158 GLU A N   
2120 C  CA  . GLU A 135 ? 0.12054 0.13803 0.14207 -0.00843 -0.02382 -0.00391 158 GLU A CA  
2121 C  C   . GLU A 135 ? 0.13144 0.16764 0.13346 -0.02310 -0.01461 -0.00809 158 GLU A C   
2122 O  O   . GLU A 135 ? 0.17076 0.29046 0.12924 -0.08146 -0.01863 0.00918  158 GLU A O   
2123 C  CB  . GLU A 135 ? 0.16425 0.19078 0.17560 -0.01337 -0.03080 -0.01245 158 GLU A CB  
2124 C  CG  . GLU A 135 ? 0.22034 0.19305 0.17124 -0.01058 -0.04159 0.02465  158 GLU A CG  
2125 C  CD  . GLU A 135 ? 0.21981 0.23547 0.17475 -0.01023 -0.03467 0.03012  158 GLU A CD  
2126 O  OE1 . GLU A 135 ? 0.19128 0.30519 0.18381 0.02866  -0.03110 0.04301  158 GLU A OE1 
2127 O  OE2 . GLU A 135 ? 0.24240 0.28266 0.17410 -0.01448 -0.04857 0.01969  158 GLU A OE2 
2134 N  N   . THR A 136 ? 0.12677 0.14448 0.12612 0.00176  -0.00436 0.00133  159 THR A N   
2135 C  CA  . THR A 136 ? 0.14295 0.16037 0.12264 0.00751  -0.00564 -0.02059 159 THR A CA  
2136 C  C   . THR A 136 ? 0.13239 0.14175 0.11150 -0.00267 0.00869  -0.00845 159 THR A C   
2137 O  O   . THR A 136 ? 0.14370 0.14722 0.12859 -0.00829 0.01430  -0.00768 159 THR A O   
2138 C  CB  . THR A 136 ? 0.15072 0.16701 0.12719 0.02108  -0.01526 -0.02036 159 THR A CB  
2139 O  OG1 . THR A 136 ? 0.17561 0.16567 0.14413 0.03751  -0.01330 -0.02757 159 THR A OG1 
2140 C  CG2 . THR A 136 ? 0.15941 0.17330 0.12242 0.00455  0.00078  -0.02634 159 THR A CG2 
2148 N  N   . PHE A 137 ? 0.13526 0.12360 0.10531 -0.00364 -0.00163 -0.00401 160 PHE A N   
2149 C  CA  . PHE A 137 ? 0.13378 0.12474 0.09723 -0.00341 0.00139  -0.00301 160 PHE A CA  
2150 C  C   . PHE A 137 ? 0.13923 0.12956 0.10369 -0.01492 0.01418  -0.00678 160 PHE A C   
2151 O  O   . PHE A 137 ? 0.16004 0.13614 0.09330 -0.01230 0.00084  -0.00686 160 PHE A O   
2152 C  CB  . PHE A 137 ? 0.13976 0.12028 0.10025 -0.00868 -0.00539 0.00673  160 PHE A CB  
2153 C  CG  . PHE A 137 ? 0.13205 0.11328 0.10074 -0.00524 0.00703  0.00314  160 PHE A CG  
2154 C  CD1 . PHE A 137 ? 0.13385 0.11986 0.10769 -0.00420 -0.00627 0.00829  160 PHE A CD1 
2155 C  CD2 . PHE A 137 ? 0.14454 0.12447 0.10642 0.00224  0.00418  0.00416  160 PHE A CD2 
2156 C  CE1 . PHE A 137 ? 0.12385 0.13278 0.11224 0.00082  0.00853  0.00774  160 PHE A CE1 
2157 C  CE2 . PHE A 137 ? 0.12935 0.13538 0.10282 -0.01283 0.00167  0.01022  160 PHE A CE2 
2158 C  CZ  . PHE A 137 ? 0.13780 0.12366 0.10944 -0.00799 0.00301  0.01097  160 PHE A CZ  
2168 N  N   . ARG A 138 ? 0.13690 0.11260 0.11143 -0.01257 0.00271  -0.00475 161 ARG A N   
2169 C  CA  . ARG A 138 ? 0.15365 0.11547 0.11576 0.00352  -0.00149 -0.00216 161 ARG A CA  
2170 C  C   . ARG A 138 ? 0.15280 0.11581 0.10168 -0.00907 0.00702  -0.01533 161 ARG A C   
2171 O  O   . ARG A 138 ? 0.18493 0.14159 0.09524 0.01613  0.00302  -0.01217 161 ARG A O   
2172 C  CB  . ARG A 138 ? 0.17621 0.12548 0.12894 -0.01647 -0.01080 -0.00466 161 ARG A CB  
2173 C  CG  . ARG A 138 ? 0.18528 0.13356 0.13417 -0.01641 -0.00651 -0.01125 161 ARG A CG  
2174 C  CD  . ARG A 138 ? 0.17051 0.12483 0.13821 -0.01847 0.00347  -0.00536 161 ARG A CD  
2175 N  NE  . ARG A 138 ? 0.12604 0.14885 0.13877 -0.01041 -0.00180 -0.01269 161 ARG A NE  
2176 C  CZ  . ARG A 138 ? 0.14918 0.14204 0.16777 -0.01624 -0.00028 -0.00144 161 ARG A CZ  
2177 N  NH1 . ARG A 138 ? 0.16147 0.18812 0.19373 0.00400  -0.00323 0.00788  161 ARG A NH1 
2178 N  NH2 . ARG A 138 ? 0.18523 0.16343 0.18365 -0.01026 -0.00528 -0.00418 161 ARG A NH2 
2192 N  N   . LEU A 139 ? 0.14857 0.10776 0.10763 -0.00665 0.01215  -0.00435 162 LEU A N   
2193 C  CA  . LEU A 139 ? 0.13184 0.12552 0.11123 -0.00037 0.00914  -0.01182 162 LEU A CA  
2194 C  C   . LEU A 139 ? 0.15642 0.12478 0.11389 0.00253  0.00306  -0.00582 162 LEU A C   
2195 O  O   . LEU A 139 ? 0.18508 0.13351 0.10409 -0.00761 0.00257  -0.00831 162 LEU A O   
2196 C  CB  . LEU A 139 ? 0.16989 0.12020 0.11975 -0.00571 -0.00312 -0.00731 162 LEU A CB  
2197 C  CG  . LEU A 139 ? 0.14710 0.11301 0.12823 0.00350  -0.01199 0.00299  162 LEU A CG  
2198 C  CD1 . LEU A 139 ? 0.16409 0.17796 0.13190 -0.03380 -0.00556 0.02042  162 LEU A CD1 
2199 C  CD2 . LEU A 139 ? 0.16252 0.15685 0.12453 0.02035  -0.00181 -0.01446 162 LEU A CD2 
2211 N  N   . ASP A 140 ? 0.16159 0.11006 0.11906 -0.01278 -0.00642 0.00872  163 ASP A N   
2212 C  CA  . ASP A 140 ? 0.15473 0.11659 0.12400 -0.01000 -0.00371 0.00092  163 ASP A CA  
2213 C  C   . ASP A 140 ? 0.14582 0.11435 0.11913 -0.00728 0.00585  -0.01263 163 ASP A C   
2214 O  O   . ASP A 140 ? 0.19071 0.13178 0.12882 0.00715  -0.01603 -0.02290 163 ASP A O   
2215 C  CB  . ASP A 140 ? 0.14590 0.11659 0.13602 -0.00218 -0.00109 -0.00177 163 ASP A CB  
2216 C  CG  . ASP A 140 ? 0.15358 0.15336 0.13925 -0.01106 -0.01285 -0.01721 163 ASP A CG  
2217 O  OD1 . ASP A 140 ? 0.16887 0.12298 0.12990 0.00000  0.00606  -0.00913 163 ASP A OD1 
2218 O  OD2 . ASP A 140 ? 0.17651 0.15663 0.15812 -0.00414 -0.00816 -0.02702 163 ASP A OD2 
2223 N  N   . ARG A 141 ? 0.14304 0.10416 0.11619 -0.00617 -0.00123 -0.01119 164 ARG A N   
2224 C  CA  . ARG A 141 ? 0.15177 0.12058 0.10671 -0.00477 0.00891  -0.01556 164 ARG A CA  
2225 C  C   . ARG A 141 ? 0.14978 0.10535 0.10595 -0.01731 -0.00132 -0.00649 164 ARG A C   
2226 O  O   . ARG A 141 ? 0.14802 0.12162 0.12057 -0.01139 0.00367  0.00002  164 ARG A O   
2227 C  CB  . ARG A 141 ? 0.15443 0.12089 0.10543 0.00116  0.01229  -0.00388 164 ARG A CB  
2228 C  CG  . ARG A 141 ? 0.13583 0.12181 0.11870 -0.02183 0.01770  -0.00824 164 ARG A CG  
2229 C  CD  . ARG A 141 ? 0.16487 0.11587 0.12395 -0.02479 0.01831  -0.01215 164 ARG A CD  
2230 N  NE  . ARG A 141 ? 0.19578 0.11499 0.12126 -0.01206 0.01960  -0.00483 164 ARG A NE  
2231 C  CZ  . ARG A 141 ? 0.16104 0.13249 0.12330 -0.02157 0.02369  -0.01048 164 ARG A CZ  
2232 N  NH1 . ARG A 141 ? 0.16687 0.14972 0.12656 -0.02889 0.01764  0.00122  164 ARG A NH1 
2233 N  NH2 . ARG A 141 ? 0.20049 0.13762 0.11258 -0.00110 0.02744  -0.00256 164 ARG A NH2 
2247 N  N   . THR A 142 ? 0.14681 0.10499 0.12117 -0.01982 0.00870  -0.00212 165 THR A N   
2248 C  CA  . THR A 142 ? 0.14998 0.11373 0.11168 -0.01590 0.00578  -0.01460 165 THR A CA  
2249 C  C   . THR A 142 ? 0.13664 0.08920 0.11503 -0.00074 0.01477  -0.00734 165 THR A C   
2250 O  O   . THR A 142 ? 0.14759 0.11875 0.11066 -0.01219 0.01015  0.00112  165 THR A O   
2251 C  CB  . THR A 142 ? 0.16314 0.13420 0.11503 -0.01130 0.01136  -0.01116 165 THR A CB  
2252 O  OG1 . THR A 142 ? 0.19227 0.11731 0.11580 -0.00379 0.00963  0.00061  165 THR A OG1 
2253 C  CG2 . THR A 142 ? 0.19155 0.13148 0.11303 -0.01823 0.01196  -0.00926 165 THR A CG2 
2261 N  N   . GLU A 143 ? 0.13165 0.11241 0.11415 -0.00741 0.01175  -0.00833 166 GLU A N   
2262 C  CA  . GLU A 143 ? 0.16686 0.09607 0.11777 -0.00100 -0.00300 -0.00490 166 GLU A CA  
2263 C  C   . GLU A 143 ? 0.15418 0.12248 0.13050 -0.00041 0.00325  0.00357  166 GLU A C   
2264 O  O   . GLU A 143 ? 0.16306 0.10678 0.14346 0.00372  0.01101  -0.00506 166 GLU A O   
2265 C  CB  . GLU A 143 ? 0.17638 0.10880 0.11491 -0.00993 0.00657  -0.00472 166 GLU A CB  
2266 C  CG  . GLU A 143 ? 0.15220 0.10936 0.12147 -0.00489 -0.00746 -0.00284 166 GLU A CG  
2267 C  CD  . GLU A 143 ? 0.16971 0.10298 0.12523 -0.00767 0.00253  0.00668  166 GLU A CD  
2268 O  OE1 . GLU A 143 ? 0.17250 0.11620 0.13327 -0.01051 0.00446  -0.00617 166 GLU A OE1 
2269 O  OE2 . GLU A 143 ? 0.17282 0.11127 0.13661 -0.01971 0.00038  0.00048  166 GLU A OE2 
2276 N  N   . PRO A 144 ? 0.17656 0.11028 0.12463 -0.00838 -0.01045 0.00647  167 PRO A N   
2277 C  CA  . PRO A 144 ? 0.18077 0.13126 0.11517 -0.02783 -0.00286 0.00740  167 PRO A CA  
2278 C  C   . PRO A 144 ? 0.19114 0.12312 0.11071 -0.03511 0.00216  0.00165  167 PRO A C   
2279 O  O   . PRO A 144 ? 0.20558 0.13947 0.11655 -0.03847 0.01312  -0.01431 167 PRO A O   
2280 C  CB  . PRO A 144 ? 0.20346 0.13269 0.12631 -0.00356 -0.00912 0.01015  167 PRO A CB  
2281 C  CG  . PRO A 144 ? 0.22767 0.12954 0.13479 0.00923  0.00208  0.01186  167 PRO A CG  
2282 C  CD  . PRO A 144 ? 0.19829 0.10111 0.13173 0.00227  -0.00258 0.00729  167 PRO A CD  
2290 N  N   . THR A 145 ? 0.17615 0.11125 0.11217 -0.01312 0.01249  -0.00128 168 THR A N   
2291 C  CA  . THR A 145 ? 0.17139 0.11748 0.12401 -0.02226 0.01633  0.00039  168 THR A CA  
2292 C  C   . THR A 145 ? 0.14672 0.12675 0.12437 -0.02005 0.01187  -0.00223 168 THR A C   
2293 O  O   . THR A 145 ? 0.16322 0.12959 0.12787 -0.01882 0.01590  -0.00133 168 THR A O   
2294 C  CB  . THR A 145 ? 0.19111 0.12348 0.12741 -0.04012 0.01893  0.00131  168 THR A CB  
2295 O  OG1 . THR A 145 ? 0.18111 0.12031 0.12140 -0.02318 0.01200  -0.00618 168 THR A OG1 
2296 C  CG2 . THR A 145 ? 0.20595 0.14814 0.13037 -0.04003 0.01981  0.00517  168 THR A CG2 
2304 N  N   . LEU A 146 ? 0.14723 0.11207 0.12048 -0.01337 0.01103  -0.00084 169 LEU A N   
2305 C  CA  . LEU A 146 ? 0.14483 0.11704 0.11670 -0.00531 0.01907  -0.00592 169 LEU A CA  
2306 C  C   . LEU A 146 ? 0.16357 0.11300 0.11750 0.00796  0.01383  0.00280  169 LEU A C   
2307 O  O   . LEU A 146 ? 0.15750 0.12306 0.12467 -0.00163 0.01308  0.00188  169 LEU A O   
2308 C  CB  . LEU A 146 ? 0.15592 0.12091 0.10869 -0.00747 0.01201  0.00043  169 LEU A CB  
2309 C  CG  . LEU A 146 ? 0.15135 0.12305 0.11475 -0.01681 0.00516  0.00019  169 LEU A CG  
2310 C  CD1 . LEU A 146 ? 0.17656 0.15747 0.13528 -0.02503 0.01464  -0.02185 169 LEU A CD1 
2311 C  CD2 . LEU A 146 ? 0.14253 0.12930 0.12767 -0.01190 0.00490  -0.01026 169 LEU A CD2 
2323 N  N   . ASN A 147 ? 0.16444 0.11081 0.11540 -0.00022 0.00165  -0.00585 170 ASN A N   
2324 C  CA  . ASN A 147 ? 0.16002 0.12583 0.11963 0.00100  0.01037  -0.00978 170 ASN A CA  
2325 C  C   . ASN A 147 ? 0.17012 0.13258 0.12110 -0.00873 0.02052  0.00365  170 ASN A C   
2326 O  O   . ASN A 147 ? 0.20127 0.14969 0.10975 -0.00456 0.01596  -0.01346 170 ASN A O   
2327 C  CB  . ASN A 147 ? 0.18884 0.14309 0.11860 -0.00606 0.02389  -0.01266 170 ASN A CB  
2328 C  CG  . ASN A 147 ? 0.17851 0.12461 0.13934 -0.01428 0.01455  -0.01715 170 ASN A CG  
2329 O  OD1 . ASN A 147 ? 0.18104 0.13390 0.15423 -0.00456 0.01983  -0.01659 170 ASN A OD1 
2330 N  ND2 . ASN A 147 ? 0.18006 0.13505 0.13518 -0.00713 0.01805  -0.01529 170 ASN A ND2 
2337 N  N   . THR A 148 ? 0.17526 0.12671 0.12302 -0.02507 0.01553  0.00030  171 THR A N   
2338 C  CA  . THR A 148 ? 0.18209 0.12570 0.12497 -0.02198 0.01524  0.00494  171 THR A CA  
2339 C  C   . THR A 148 ? 0.17430 0.13017 0.11655 -0.01998 0.01435  -0.00031 171 THR A C   
2340 O  O   . THR A 148 ? 0.19498 0.13038 0.11372 -0.01249 0.02980  0.00031  171 THR A O   
2341 C  CB  . THR A 148 ? 0.19960 0.13197 0.13142 -0.02960 0.02922  0.00820  171 THR A CB  
2342 O  OG1 . THR A 148 ? 0.19327 0.12861 0.12878 -0.01724 0.02434  0.00344  171 THR A OG1 
2343 C  CG2 . THR A 148 ? 0.20834 0.11788 0.13351 -0.01916 0.01880  0.00265  171 THR A CG2 
2351 N  N   . ALA A 149 ? 0.17949 0.12261 0.11356 -0.00533 0.00792  -0.00382 172 ALA A N   
2352 C  CA  . ALA A 149 ? 0.17442 0.13400 0.11311 -0.01896 0.00744  0.00659  172 ALA A CA  
2353 C  C   . ALA A 149 ? 0.18231 0.13697 0.11789 -0.01474 0.01730  0.00469  172 ALA A C   
2354 O  O   . ALA A 149 ? 0.21782 0.14821 0.11702 -0.01927 0.03523  -0.00501 172 ALA A O   
2355 C  CB  . ALA A 149 ? 0.20070 0.13025 0.11195 -0.01185 0.00239  0.00489  172 ALA A CB  
2361 N  N   . ILE A 150 ? 0.17824 0.14417 0.12492 -0.01798 0.02018  -0.00343 173 ILE A N   
2362 C  CA  . ILE A 150 ? 0.19245 0.15641 0.13675 -0.00765 0.03519  -0.00594 173 ILE A CA  
2363 C  C   . ILE A 150 ? 0.18945 0.17190 0.13468 -0.02447 0.03434  -0.01472 173 ILE A C   
2364 O  O   . ILE A 150 ? 0.19778 0.17217 0.13279 -0.02411 0.02492  -0.00832 173 ILE A O   
2365 C  CB  . ILE A 150 ? 0.20213 0.15807 0.16455 -0.04371 0.03552  -0.00490 173 ILE A CB  
2366 C  CG1 . ILE A 150 ? 0.22416 0.15631 0.17720 -0.05106 0.03889  -0.00604 173 ILE A CG1 
2367 C  CG2 . ILE A 150 ? 0.21150 0.20914 0.17464 -0.04917 0.02367  -0.00387 173 ILE A CG2 
2368 C  CD1 . ILE A 150 ? 0.24439 0.18073 0.18890 -0.04557 0.02168  -0.02092 173 ILE A CD1 
2380 N  N   . PRO A 151 ? 0.19625 0.18863 0.13905 0.00654  0.02864  -0.01266 174 PRO A N   
2381 C  CA  . PRO A 151 ? 0.19423 0.21512 0.14836 0.00281  0.03819  -0.01609 174 PRO A CA  
2382 C  C   . PRO A 151 ? 0.18003 0.19815 0.16364 -0.01796 0.03889  -0.01516 174 PRO A C   
2383 O  O   . PRO A 151 ? 0.19435 0.22897 0.17417 -0.03282 0.03068  -0.01047 174 PRO A O   
2384 C  CB  . PRO A 151 ? 0.23441 0.24981 0.14853 0.04259  0.02912  -0.01992 174 PRO A CB  
2385 C  CG  . PRO A 151 ? 0.25670 0.25026 0.14020 0.04183  0.02352  -0.01640 174 PRO A CG  
2386 C  CD  . PRO A 151 ? 0.21895 0.21529 0.13406 0.01209  0.03177  -0.00334 174 PRO A CD  
2394 N  N   . GLY A 152 ? 0.18469 0.20593 0.16796 -0.00092 0.03453  -0.01706 175 GLY A N   
2395 C  CA  . GLY A 152 ? 0.17863 0.21879 0.16957 -0.02634 0.03356  -0.02330 175 GLY A CA  
2396 C  C   . GLY A 152 ? 0.18360 0.21015 0.16810 -0.00207 0.02129  -0.02838 175 GLY A C   
2397 O  O   . GLY A 152 ? 0.20606 0.26725 0.18672 0.00554  0.00704  -0.01709 175 GLY A O   
2401 N  N   . ASP A 153 ? 0.16090 0.18804 0.15487 -0.01713 0.03249  -0.01479 176 ASP A N   
2402 C  CA  . ASP A 153 ? 0.17632 0.17285 0.15388 -0.02302 0.03207  -0.01273 176 ASP A CA  
2403 C  C   . ASP A 153 ? 0.16693 0.17034 0.14692 -0.01697 0.02287  -0.00854 176 ASP A C   
2404 O  O   . ASP A 153 ? 0.17596 0.16213 0.13902 -0.02326 0.02440  -0.00818 176 ASP A O   
2405 C  CB  . ASP A 153 ? 0.17261 0.16768 0.15388 -0.02149 0.02416  -0.00531 176 ASP A CB  
2406 C  CG  . ASP A 153 ? 0.18009 0.15286 0.16021 -0.02303 0.00697  -0.01275 176 ASP A CG  
2407 O  OD1 . ASP A 153 ? 0.19300 0.16965 0.15758 -0.03256 0.01309  -0.00739 176 ASP A OD1 
2408 O  OD2 . ASP A 153 ? 0.22582 0.16442 0.16543 -0.01367 -0.00426 -0.02462 176 ASP A OD2 
2413 N  N   . PRO A 154 ? 0.16834 0.17547 0.14642 -0.01883 0.00988  -0.00539 177 PRO A N   
2414 C  CA  . PRO A 154 ? 0.15787 0.17835 0.14643 -0.01980 0.00960  0.00202  177 PRO A CA  
2415 C  C   . PRO A 154 ? 0.15033 0.15629 0.13722 -0.02550 0.00040  -0.00364 177 PRO A C   
2416 O  O   . PRO A 154 ? 0.14910 0.15105 0.13179 -0.02009 -0.00573 0.00342  177 PRO A O   
2417 C  CB  . PRO A 154 ? 0.17363 0.21139 0.16473 -0.00423 -0.00559 0.00455  177 PRO A CB  
2418 C  CG  . PRO A 154 ? 0.16705 0.24201 0.16628 -0.00806 -0.00870 0.00946  177 PRO A CG  
2419 C  CD  . PRO A 154 ? 0.16877 0.21842 0.15780 -0.02231 -0.00811 -0.00178 177 PRO A CD  
2427 N  N   . ARG A 155 ? 0.15056 0.14371 0.13133 -0.04002 0.00765  -0.00497 178 ARG A N   
2428 C  CA  . ARG A 155 ? 0.15351 0.13054 0.11982 -0.02685 0.01106  -0.00658 178 ARG A CA  
2429 C  C   . ARG A 155 ? 0.15114 0.12697 0.11648 -0.01934 0.01201  0.00186  178 ARG A C   
2430 O  O   . ARG A 155 ? 0.17193 0.13131 0.09968 -0.02089 0.00151  -0.00030 178 ARG A O   
2431 C  CB  . ARG A 155 ? 0.17499 0.14581 0.12877 -0.03646 0.00503  -0.00942 178 ARG A CB  
2432 C  CG  . ARG A 155 ? 0.20757 0.14933 0.13819 -0.06238 -0.01139 -0.00083 178 ARG A CG  
2433 C  CD  . ARG A 155 ? 0.22359 0.14186 0.14256 -0.04224 0.00104  -0.00670 178 ARG A CD  
2434 N  NE  . ARG A 155 ? 0.19835 0.13833 0.14480 -0.04754 0.02054  -0.00411 178 ARG A NE  
2435 C  CZ  . ARG A 155 ? 0.20511 0.14517 0.15586 -0.03666 0.02673  -0.01456 178 ARG A CZ  
2436 N  NH1 . ARG A 155 ? 0.21147 0.15548 0.16002 -0.05095 0.03074  -0.02395 178 ARG A NH1 
2437 N  NH2 . ARG A 155 ? 0.22969 0.15875 0.15264 -0.03821 0.03905  -0.00977 178 ARG A NH2 
2451 N  N   . ASP A 156 ? 0.14493 0.12344 0.10544 -0.02411 0.00490  -0.00031 179 ASP A N   
2452 C  CA  . ASP A 156 ? 0.15757 0.10795 0.10637 -0.00220 0.00940  0.00639  179 ASP A CA  
2453 C  C   . ASP A 156 ? 0.15074 0.11346 0.09979 -0.01307 0.00232  -0.00992 179 ASP A C   
2454 O  O   . ASP A 156 ? 0.15081 0.11918 0.10643 -0.00352 -0.00301 -0.00814 179 ASP A O   
2455 C  CB  . ASP A 156 ? 0.16586 0.11815 0.10532 -0.01145 0.00249  -0.00171 179 ASP A CB  
2456 C  CG  . ASP A 156 ? 0.15627 0.11860 0.10589 -0.00240 0.00300  -0.00835 179 ASP A CG  
2457 O  OD1 . ASP A 156 ? 0.15449 0.12289 0.10891 -0.00532 -0.00126 -0.01219 179 ASP A OD1 
2458 O  OD2 . ASP A 156 ? 0.18035 0.12105 0.11770 -0.01169 0.00936  -0.01136 179 ASP A OD2 
2463 N  N   . THR A 157 ? 0.14100 0.11572 0.10765 -0.01205 0.00443  -0.00294 180 THR A N   
2464 C  CA  . THR A 157 ? 0.13687 0.12448 0.10899 -0.01890 0.00724  -0.00295 180 THR A CA  
2465 C  C   . THR A 157 ? 0.13946 0.12307 0.09862 -0.00670 0.00722  -0.00797 180 THR A C   
2466 O  O   . THR A 157 ? 0.14777 0.12334 0.09742 -0.00873 0.00391  -0.00559 180 THR A O   
2467 C  CB  . THR A 157 ? 0.13079 0.11879 0.11751 -0.00746 0.00000  -0.00049 180 THR A CB  
2468 O  OG1 . THR A 157 ? 0.13609 0.14236 0.12933 -0.01387 -0.00414 -0.00004 180 THR A OG1 
2469 C  CG2 . THR A 157 ? 0.14930 0.13798 0.11632 -0.00480 0.00203  -0.00410 180 THR A CG2 
2477 N  N   . THR A 158 ? 0.13838 0.11757 0.09919 -0.01471 0.00733  -0.00410 181 THR A N   
2478 C  CA  . THR A 158 ? 0.13226 0.10917 0.11182 -0.01147 0.00161  0.00270  181 THR A CA  
2479 C  C   . THR A 158 ? 0.14907 0.11235 0.10706 -0.00947 0.00162  -0.01063 181 THR A C   
2480 O  O   . THR A 158 ? 0.17040 0.13143 0.10613 -0.00725 0.01062  -0.00443 181 THR A O   
2481 C  CB  . THR A 158 ? 0.15773 0.10849 0.11668 -0.00081 -0.00394 0.00558  181 THR A CB  
2482 O  OG1 . THR A 158 ? 0.16142 0.11310 0.10505 -0.00532 0.00117  0.00696  181 THR A OG1 
2483 C  CG2 . THR A 158 ? 0.13129 0.12232 0.12870 -0.01123 0.00313  -0.00167 181 THR A CG2 
2491 N  N   . SER A 159 ? 0.15804 0.10824 0.10764 -0.00773 0.01998  -0.00557 182 SER A N   
2492 C  CA  . SER A 159 ? 0.14034 0.12531 0.11212 -0.01181 0.00683  -0.00682 182 SER A CA  
2493 C  C   . SER A 159 ? 0.13321 0.11090 0.12132 -0.00158 0.01043  0.00548  182 SER A C   
2494 O  O   . SER A 159 ? 0.13944 0.13102 0.11457 -0.00051 0.01622  -0.00024 182 SER A O   
2495 C  CB  . SER A 159 ? 0.13961 0.12453 0.12120 0.00581  0.00674  -0.00792 182 SER A CB  
2496 O  OG  . SER A 159 ? 0.13653 0.12871 0.12802 -0.00099 0.00805  0.00641  182 SER A OG  
2502 N  N   . PRO A 160 ? 0.15234 0.10989 0.10810 -0.00355 0.01392  -0.01560 183 PRO A N   
2503 C  CA  . PRO A 160 ? 0.14500 0.12847 0.10167 0.00923  0.00594  0.00181  183 PRO A CA  
2504 C  C   . PRO A 160 ? 0.12865 0.11531 0.10167 -0.01236 0.01129  -0.00531 183 PRO A C   
2505 O  O   . PRO A 160 ? 0.14750 0.13401 0.09446 -0.01570 0.00511  -0.01154 183 PRO A O   
2506 C  CB  . PRO A 160 ? 0.17187 0.12745 0.10224 -0.01070 0.00959  -0.00958 183 PRO A CB  
2507 C  CG  . PRO A 160 ? 0.16011 0.14076 0.11100 -0.00464 0.01242  -0.00283 183 PRO A CG  
2508 C  CD  . PRO A 160 ? 0.14635 0.12788 0.11487 -0.01712 0.01992  0.00158  183 PRO A CD  
2516 N  N   . ARG A 161 ? 0.14247 0.11880 0.11318 -0.00639 0.00804  -0.00641 184 ARG A N   
2517 C  CA  . ARG A 161 ? 0.16387 0.10977 0.11651 -0.01006 0.00984  0.01261  184 ARG A CA  
2518 C  C   . ARG A 161 ? 0.13806 0.11634 0.11200 -0.00593 -0.00247 0.01360  184 ARG A C   
2519 O  O   . ARG A 161 ? 0.16434 0.13323 0.10825 -0.00806 -0.00560 0.01078  184 ARG A O   
2520 C  CB  . ARG A 161 ? 0.17088 0.12783 0.13159 0.01505  0.03755  0.00904  184 ARG A CB  
2521 C  CG  . ARG A 161 ? 0.17939 0.14795 0.13603 0.01658  0.02321  0.00967  184 ARG A CG  
2522 C  CD  . ARG A 161 ? 0.20441 0.15349 0.14411 0.02995  0.01781  0.01557  184 ARG A CD  
2523 N  NE  . ARG A 161 ? 0.21605 0.14283 0.15508 0.02760  0.01413  0.01489  184 ARG A NE  
2524 C  CZ  . ARG A 161 ? 0.20435 0.15844 0.16640 0.01688  0.02412  0.02169  184 ARG A CZ  
2525 N  NH1 . ARG A 161 ? 0.21714 0.19753 0.17513 0.01206  0.02329  0.01573  184 ARG A NH1 
2526 N  NH2 . ARG A 161 ? 0.19917 0.18663 0.17754 0.02749  0.03686  0.00737  184 ARG A NH2 
2540 N  N   . ALA A 162 ? 0.13714 0.13654 0.11297 -0.00540 -0.00505 0.00512  185 ALA A N   
2541 C  CA  . ALA A 162 ? 0.13675 0.14592 0.11303 -0.00394 0.00060  -0.00430 185 ALA A CA  
2542 C  C   . ALA A 162 ? 0.14599 0.12901 0.11004 -0.00561 0.00557  0.00236  185 ALA A C   
2543 O  O   . ALA A 162 ? 0.13529 0.13735 0.11036 -0.00812 -0.00308 0.00469  185 ALA A O   
2544 C  CB  . ALA A 162 ? 0.14873 0.16550 0.11795 -0.00694 -0.00853 -0.01586 185 ALA A CB  
2550 N  N   A MET A 163 ? 0.14745 0.12335 0.10630 -0.00981 0.00947  0.00252  186 MET A N   
2551 N  N   B MET A 163 ? 0.14190 0.12145 0.10404 -0.01942 0.00496  -0.00581 186 MET A N   
2552 C  CA  A MET A 163 ? 0.14473 0.12033 0.10533 -0.00509 0.01510  0.00960  186 MET A CA  
2553 C  CA  B MET A 163 ? 0.14209 0.12122 0.10084 -0.01114 0.00895  -0.00215 186 MET A CA  
2554 C  C   A MET A 163 ? 0.14591 0.13010 0.10145 -0.01426 0.00493  0.00804  186 MET A C   
2555 C  C   B MET A 163 ? 0.11563 0.13776 0.10281 -0.00511 -0.00512 0.00245  186 MET A C   
2556 O  O   A MET A 163 ? 0.16748 0.11995 0.09992 -0.02807 0.00961  0.01123  186 MET A O   
2557 O  O   B MET A 163 ? 0.11509 0.14192 0.10835 0.00771  -0.00046 0.01148  186 MET A O   
2558 C  CB  A MET A 163 ? 0.14910 0.11767 0.11508 0.00537  0.01087  0.01697  186 MET A CB  
2559 C  CB  B MET A 163 ? 0.18188 0.12528 0.10699 -0.02155 -0.00031 -0.00583 186 MET A CB  
2560 C  CG  A MET A 163 ? 0.12764 0.12183 0.12302 0.02678  0.00077  0.02099  186 MET A CG  
2561 C  CG  B MET A 163 ? 0.18854 0.14003 0.10955 -0.01267 -0.01755 -0.00667 186 MET A CG  
2562 S  SD  A MET A 163 ? 0.11733 0.12565 0.13232 0.03362  0.00988  0.01904  186 MET A SD  
2563 S  SD  B MET A 163 ? 0.20270 0.16498 0.11509 -0.02146 -0.01244 -0.01842 186 MET A SD  
2564 C  CE  A MET A 163 ? 0.15222 0.12925 0.13828 0.01682  0.00068  0.01769  186 MET A CE  
2565 C  CE  B MET A 163 ? 0.21372 0.13887 0.11405 -0.00875 -0.01171 -0.00388 186 MET A CE  
2584 N  N   . ALA A 164 ? 0.12800 0.13178 0.09839 -0.01172 0.00282  0.00810  187 ALA A N   
2585 C  CA  . ALA A 164 ? 0.12878 0.12622 0.09699 -0.01160 0.00282  0.01100  187 ALA A CA  
2586 C  C   . ALA A 164 ? 0.11196 0.13501 0.10595 -0.01922 -0.01262 0.00005  187 ALA A C   
2587 O  O   . ALA A 164 ? 0.12463 0.14147 0.10434 -0.02521 -0.00379 0.00757  187 ALA A O   
2588 C  CB  . ALA A 164 ? 0.15713 0.12153 0.09718 -0.01589 0.01362  0.00965  187 ALA A CB  
2595 N  N   . GLN A 165 ? 0.11542 0.13435 0.10819 -0.01784 -0.00090 0.00600  188 GLN A N   
2596 C  CA  . GLN A 165 ? 0.14227 0.14677 0.10465 -0.01476 0.00295  0.02047  188 GLN A CA  
2597 C  C   . GLN A 165 ? 0.13076 0.14061 0.10679 -0.00466 -0.00511 0.01612  188 GLN A C   
2598 O  O   . GLN A 165 ? 0.15129 0.14071 0.10090 -0.02255 0.00999  0.01426  188 GLN A O   
2599 C  CB  . GLN A 165 ? 0.16030 0.14387 0.11261 -0.00573 -0.00258 0.02630  188 GLN A CB  
2600 C  CG  . GLN A 165 ? 0.15263 0.14582 0.12533 0.00821  -0.00313 0.01778  188 GLN A CG  
2601 C  CD  . GLN A 165 ? 0.19630 0.16735 0.14535 0.00292  0.00282  -0.00639 188 GLN A CD  
2602 O  OE1 . GLN A 165 ? 0.23834 0.16146 0.14353 -0.02141 0.01373  0.00939  188 GLN A OE1 
2603 N  NE2 . GLN A 165 ? 0.25449 0.19970 0.19406 0.01078  0.04688  -0.01781 188 GLN A NE2 
2612 N  N   . THR A 166 ? 0.14594 0.14615 0.10848 -0.00095 -0.00239 0.01510  189 THR A N   
2613 C  CA  . THR A 166 ? 0.12365 0.14271 0.10982 -0.01172 0.00679  0.00982  189 THR A CA  
2614 C  C   . THR A 166 ? 0.13945 0.13828 0.10860 -0.02759 0.01718  0.00654  189 THR A C   
2615 O  O   . THR A 166 ? 0.14195 0.13790 0.10985 -0.01588 0.00425  -0.00001 189 THR A O   
2616 C  CB  . THR A 166 ? 0.13886 0.15813 0.12625 -0.01744 0.01528  0.00149  189 THR A CB  
2617 O  OG1 . THR A 166 ? 0.16939 0.15869 0.11917 -0.03577 0.00130  0.00611  189 THR A OG1 
2618 C  CG2 . THR A 166 ? 0.19572 0.17468 0.17399 -0.03188 0.02831  -0.02459 189 THR A CG2 
2626 N  N   . LEU A 167 ? 0.14154 0.15938 0.10358 -0.00669 0.00952  0.01093  190 LEU A N   
2627 C  CA  . LEU A 167 ? 0.13283 0.16508 0.10461 -0.00964 0.00641  0.00342  190 LEU A CA  
2628 C  C   . LEU A 167 ? 0.12841 0.16619 0.10240 -0.00918 0.00689  0.00755  190 LEU A C   
2629 O  O   . LEU A 167 ? 0.14122 0.17257 0.11065 -0.01556 0.00927  0.01323  190 LEU A O   
2630 C  CB  . LEU A 167 ? 0.14631 0.13673 0.10500 -0.01941 0.00073  0.00618  190 LEU A CB  
2631 C  CG  . LEU A 167 ? 0.14948 0.11660 0.10962 -0.00498 0.00747  0.00599  190 LEU A CG  
2632 C  CD1 . LEU A 167 ? 0.16525 0.15148 0.11562 0.00105  0.00982  0.00233  190 LEU A CD1 
2633 C  CD2 . LEU A 167 ? 0.16147 0.13717 0.10588 -0.00649 -0.00311 0.00308  190 LEU A CD2 
2645 N  N   A ARG A 168 ? 0.13329 0.16105 0.10163 -0.02463 0.00662  -0.00048 191 ARG A N   
2646 N  N   B ARG A 168 ? 0.14851 0.15642 0.10060 -0.00963 0.01378  0.00018  191 ARG A N   
2647 C  CA  A ARG A 168 ? 0.13214 0.14934 0.10546 -0.03505 0.00628  -0.00388 191 ARG A CA  
2648 C  CA  B ARG A 168 ? 0.16347 0.14758 0.10439 0.00446  0.02083  0.00275  191 ARG A CA  
2649 C  C   A ARG A 168 ? 0.12092 0.13169 0.10902 -0.05304 -0.00366 -0.00059 191 ARG A C   
2650 C  C   B ARG A 168 ? 0.16741 0.12957 0.10993 -0.00528 0.01282  0.00368  191 ARG A C   
2651 O  O   A ARG A 168 ? 0.11092 0.13905 0.11051 -0.03947 -0.00708 0.00635  191 ARG A O   
2652 O  O   B ARG A 168 ? 0.19599 0.11492 0.11332 0.01737  0.01715  0.01461  191 ARG A O   
2653 C  CB  A ARG A 168 ? 0.13406 0.15646 0.10945 -0.03767 -0.00338 -0.02149 191 ARG A CB  
2654 C  CB  B ARG A 168 ? 0.17900 0.16508 0.10989 0.00697  0.01780  -0.00596 191 ARG A CB  
2655 C  CG  A ARG A 168 ? 0.15980 0.15691 0.12211 -0.02487 -0.00273 -0.02669 191 ARG A CG  
2656 C  CG  B ARG A 168 ? 0.20746 0.16187 0.12868 0.01168  0.01327  -0.02256 191 ARG A CG  
2657 C  CD  A ARG A 168 ? 0.18111 0.13434 0.13167 -0.04946 -0.00898 -0.01183 191 ARG A CD  
2658 C  CD  B ARG A 168 ? 0.22126 0.14883 0.13272 0.02759  0.02284  -0.01109 191 ARG A CD  
2659 N  NE  A ARG A 168 ? 0.19532 0.15933 0.13283 -0.03869 -0.02383 0.01838  191 ARG A NE  
2660 N  NE  B ARG A 168 ? 0.22269 0.18000 0.14179 0.04107  0.01344  -0.01278 191 ARG A NE  
2661 C  CZ  A ARG A 168 ? 0.23264 0.13882 0.12335 -0.04145 -0.03338 0.00538  191 ARG A CZ  
2662 C  CZ  B ARG A 168 ? 0.23831 0.13844 0.14501 0.02773  0.00079  0.00085  191 ARG A CZ  
2663 N  NH1 A ARG A 168 ? 0.25144 0.11826 0.12763 -0.02467 -0.04112 0.01771  191 ARG A NH1 
2664 N  NH1 B ARG A 168 ? 0.21590 0.09426 0.12834 0.05758  0.02189  -0.00383 191 ARG A NH1 
2665 N  NH2 A ARG A 168 ? 0.26632 0.16643 0.12142 -0.08290 -0.00692 0.00580  191 ARG A NH2 
2666 N  NH2 B ARG A 168 ? 0.25323 0.11200 0.15399 0.01647  -0.02353 0.01433  191 ARG A NH2 
2693 N  N   . ASN A 169 ? 0.14466 0.12586 0.10468 -0.01267 0.00788  0.00582  192 ASN A N   
2694 C  CA  . ASN A 169 ? 0.14484 0.12411 0.10794 0.00550  0.00169  0.01231  192 ASN A CA  
2695 C  C   . ASN A 169 ? 0.14559 0.12567 0.11839 0.00257  0.00125  0.01481  192 ASN A C   
2696 O  O   . ASN A 169 ? 0.15901 0.12207 0.13321 -0.01026 0.00665  0.01656  192 ASN A O   
2697 C  CB  . ASN A 169 ? 0.12898 0.13394 0.11545 0.00828  0.01004  0.00575  192 ASN A CB  
2698 C  CG  . ASN A 169 ? 0.15436 0.12876 0.11963 0.01229  0.00693  -0.00368 192 ASN A CG  
2699 O  OD1 . ASN A 169 ? 0.18638 0.14510 0.11142 0.01368  0.00391  0.00558  192 ASN A OD1 
2700 N  ND2 . ASN A 169 ? 0.18761 0.15883 0.13507 -0.00558 -0.00489 -0.01984 192 ASN A ND2 
2708 N  N   . LEU A 170 ? 0.13559 0.12076 0.11450 -0.00763 0.00065  0.01319  193 LEU A N   
2709 C  CA  . LEU A 170 ? 0.12976 0.11809 0.12788 0.00635  0.00011  0.00929  193 LEU A CA  
2710 C  C   . LEU A 170 ? 0.12479 0.11947 0.13224 0.01667  0.00678  0.01054  193 LEU A C   
2711 O  O   . LEU A 170 ? 0.14560 0.14083 0.13986 -0.00503 -0.00144 -0.00562 193 LEU A O   
2712 C  CB  . LEU A 170 ? 0.14749 0.12036 0.13737 0.00618  0.01492  0.00351  193 LEU A CB  
2713 C  CG  . LEU A 170 ? 0.15632 0.10604 0.13992 -0.00686 -0.00226 0.00732  193 LEU A CG  
2714 C  CD1 . LEU A 170 ? 0.18010 0.13150 0.15471 -0.02479 0.00122  0.01837  193 LEU A CD1 
2715 C  CD2 . LEU A 170 ? 0.16055 0.12797 0.14880 -0.01264 -0.01761 0.00249  193 LEU A CD2 
2727 N  N   . THR A 171 ? 0.13849 0.12356 0.12899 -0.00476 0.00976  0.00324  194 THR A N   
2728 C  CA  . THR A 171 ? 0.14098 0.13279 0.13665 -0.01470 -0.00066 0.00513  194 THR A CA  
2729 C  C   . THR A 171 ? 0.14016 0.13673 0.14545 -0.01402 0.01259  0.00710  194 THR A C   
2730 O  O   . THR A 171 ? 0.16823 0.15219 0.18522 -0.01570 -0.00100 0.01244  194 THR A O   
2731 C  CB  . THR A 171 ? 0.12685 0.13707 0.14166 -0.00646 0.00098  0.01155  194 THR A CB  
2732 O  OG1 . THR A 171 ? 0.15560 0.14314 0.14096 -0.01245 0.00147  0.00744  194 THR A OG1 
2733 C  CG2 . THR A 171 ? 0.17171 0.12696 0.14368 0.00504  -0.00413 0.01050  194 THR A CG2 
2741 N  N   . LEU A 172 ? 0.15201 0.11762 0.12986 -0.01306 0.00214  0.01244  195 LEU A N   
2742 C  CA  . LEU A 172 ? 0.16520 0.12583 0.13380 -0.01390 -0.01190 0.00956  195 LEU A CA  
2743 C  C   . LEU A 172 ? 0.18716 0.13646 0.13988 -0.02963 -0.00925 0.02393  195 LEU A C   
2744 O  O   . LEU A 172 ? 0.26260 0.17135 0.15721 -0.07596 -0.03806 0.03234  195 LEU A O   
2745 C  CB  . LEU A 172 ? 0.17604 0.12782 0.13744 -0.00532 -0.02037 0.00683  195 LEU A CB  
2746 C  CG  . LEU A 172 ? 0.18311 0.12776 0.13921 -0.00147 -0.01134 0.00668  195 LEU A CG  
2747 C  CD1 . LEU A 172 ? 0.20808 0.15735 0.14715 -0.00846 -0.01309 -0.00678 195 LEU A CD1 
2748 C  CD2 . LEU A 172 ? 0.21740 0.14901 0.14038 -0.00157 -0.02909 0.01658  195 LEU A CD2 
2760 N  N   . GLY A 173 ? 0.17674 0.12619 0.12026 -0.00733 -0.00199 0.01686  196 GLY A N   
2761 C  CA  . GLY A 173 ? 0.14417 0.14236 0.12035 0.00111  0.00745  0.01202  196 GLY A CA  
2762 C  C   . GLY A 173 ? 0.17034 0.12616 0.12755 -0.00867 0.01386  0.01795  196 GLY A C   
2763 O  O   . GLY A 173 ? 0.16853 0.16110 0.14174 0.00132  0.00652  -0.00793 196 GLY A O   
2767 N  N   . LYS A 174 ? 0.20338 0.14021 0.12180 0.00612  0.01235  0.00898  197 LYS A N   
2768 C  CA  . LYS A 174 ? 0.23408 0.12813 0.12659 -0.00606 0.02909  0.02468  197 LYS A CA  
2769 C  C   . LYS A 174 ? 0.20408 0.14605 0.12367 0.01843  0.00261  0.01256  197 LYS A C   
2770 O  O   . LYS A 174 ? 0.24733 0.13710 0.11986 0.02016  0.01521  0.00284  197 LYS A O   
2771 C  CB  . LYS A 174 ? 0.30196 0.13880 0.13611 -0.02829 0.01036  0.01238  197 LYS A CB  
2772 C  CG  . LYS A 174 ? 0.31543 0.13617 0.14847 -0.00995 0.00656  0.00901  197 LYS A CG  
2773 C  CD  . LYS A 174 ? 0.36264 0.17755 0.15686 -0.02588 0.00029  0.00542  197 LYS A CD  
2774 C  CE  . LYS A 174 ? 0.39601 0.16375 0.16266 -0.00737 -0.00663 0.00880  197 LYS A CE  
2775 N  NZ  . LYS A 174 ? 0.41256 0.18300 0.17749 -0.03005 -0.01736 -0.00326 197 LYS A NZ  
2789 N  N   . ALA A 175 ? 0.19306 0.12707 0.12568 0.01542  -0.00316 0.00519  198 ALA A N   
2790 C  CA  . ALA A 175 ? 0.18203 0.12332 0.13681 0.00639  -0.00448 -0.00187 198 ALA A CA  
2791 C  C   . ALA A 175 ? 0.17768 0.12200 0.13797 0.00036  0.00216  -0.00144 198 ALA A C   
2792 O  O   . ALA A 175 ? 0.20325 0.15193 0.14967 0.01191  -0.00057 -0.01682 198 ALA A O   
2793 C  CB  . ALA A 175 ? 0.15158 0.13205 0.14392 0.00427  0.00743  0.00630  198 ALA A CB  
2799 N  N   . LEU A 176 ? 0.16574 0.12082 0.12938 0.01291  0.00349  0.00293  199 LEU A N   
2800 C  CA  . LEU A 176 ? 0.17248 0.13343 0.13631 0.02684  0.01381  0.00582  199 LEU A CA  
2801 C  C   . LEU A 176 ? 0.18507 0.13898 0.14892 0.02818  0.02165  0.01897  199 LEU A C   
2802 O  O   . LEU A 176 ? 0.19788 0.14821 0.15867 0.00468  0.03762  0.01920  199 LEU A O   
2803 C  CB  . LEU A 176 ? 0.13495 0.12816 0.14621 0.01424  0.01666  0.00793  199 LEU A CB  
2804 C  CG  . LEU A 176 ? 0.16110 0.13976 0.14893 0.00515  0.00380  0.01510  199 LEU A CG  
2805 C  CD1 . LEU A 176 ? 0.16201 0.15027 0.14817 -0.00897 0.01027  0.03138  199 LEU A CD1 
2806 C  CD2 . LEU A 176 ? 0.20083 0.15622 0.16029 -0.00904 -0.01452 0.01377  199 LEU A CD2 
2818 N  N   . GLY A 177 ? 0.18519 0.15999 0.15941 0.00206  0.04326  0.01860  200 GLY A N   
2819 C  CA  . GLY A 177 ? 0.20259 0.16604 0.18772 0.01806  0.04511  0.02510  200 GLY A CA  
2820 C  C   . GLY A 177 ? 0.18394 0.16043 0.20491 0.01624  0.04868  0.03510  200 GLY A C   
2821 O  O   . GLY A 177 ? 0.19072 0.17440 0.19136 0.00108  0.04724  0.03982  200 GLY A O   
2825 N  N   . ASP A 178 ? 0.20723 0.16950 0.23309 0.01953  0.04704  0.05170  201 ASP A N   
2826 C  CA  . ASP A 178 ? 0.21617 0.15478 0.26310 -0.00286 0.04175  0.05106  201 ASP A CA  
2827 C  C   . ASP A 178 ? 0.18849 0.12891 0.24260 -0.00255 0.04857  0.03527  201 ASP A C   
2828 O  O   . ASP A 178 ? 0.19954 0.16105 0.25103 -0.01078 0.04499  0.01725  201 ASP A O   
2829 C  CB  . ASP A 178 ? 0.25633 0.19001 0.30666 0.00738  0.03517  0.06337  201 ASP A CB  
2830 C  CG  . ASP A 178 ? 0.29801 0.23574 0.34014 -0.01046 0.04188  0.06054  201 ASP A CG  
2831 O  OD1 . ASP A 178 ? 0.30067 0.25029 0.34502 0.01035  0.04364  0.04973  201 ASP A OD1 
2832 O  OD2 . ASP A 178 ? 0.36643 0.26934 0.36245 -0.01982 0.02454  0.06183  201 ASP A OD2 
2837 N  N   . SER A 179 ? 0.16837 0.14967 0.21642 -0.00236 0.05136  0.02788  202 SER A N   
2838 C  CA  . SER A 179 ? 0.16979 0.14866 0.20538 -0.01328 0.03687  0.02104  202 SER A CA  
2839 C  C   . SER A 179 ? 0.14964 0.14353 0.19952 -0.00014 0.03448  0.01793  202 SER A C   
2840 O  O   . SER A 179 ? 0.13578 0.14168 0.20599 -0.00130 0.02751  0.01446  202 SER A O   
2841 C  CB  . SER A 179 ? 0.16459 0.16495 0.20301 -0.00543 0.03830  0.01018  202 SER A CB  
2842 O  OG  . SER A 179 ? 0.17099 0.16383 0.21234 0.00238  0.03928  0.00728  202 SER A OG  
2848 N  N   . GLN A 180 ? 0.15355 0.15279 0.19310 -0.01091 0.04264  0.03148  203 GLN A N   
2849 C  CA  . GLN A 180 ? 0.13560 0.14041 0.17954 -0.00061 0.02768  0.01172  203 GLN A CA  
2850 C  C   . GLN A 180 ? 0.15991 0.12738 0.18031 -0.01085 0.03071  0.00084  203 GLN A C   
2851 O  O   . GLN A 180 ? 0.14881 0.13168 0.17972 -0.00381 0.02225  0.00665  203 GLN A O   
2852 C  CB  . GLN A 180 ? 0.16839 0.13599 0.17528 -0.00515 0.02739  0.00506  203 GLN A CB  
2853 C  CG  . GLN A 180 ? 0.18021 0.17134 0.17943 0.00002  0.03821  0.00435  203 GLN A CG  
2854 C  CD  . GLN A 180 ? 0.21069 0.21399 0.18657 0.03058  0.04889  -0.00512 203 GLN A CD  
2855 O  OE1 . GLN A 180 ? 0.22755 0.20763 0.18360 -0.02242 0.05165  0.00149  203 GLN A OE1 
2856 N  NE2 . GLN A 180 ? 0.27464 0.28181 0.19914 0.04915  0.05911  -0.00933 203 GLN A NE2 
2865 N  N   . ARG A 181 ? 0.15666 0.12590 0.18102 -0.00090 0.03499  0.00471  204 ARG A N   
2866 C  CA  A ARG A 181 ? 0.13592 0.12509 0.18854 -0.01476 0.02628  0.00996  204 ARG A CA  
2867 C  CA  B ARG A 181 ? 0.15836 0.13613 0.18854 -0.00559 0.02495  0.00395  204 ARG A CA  
2868 C  C   . ARG A 181 ? 0.13221 0.13460 0.19649 -0.01756 0.01924  0.00180  204 ARG A C   
2869 O  O   . ARG A 181 ? 0.14455 0.13338 0.19286 -0.00694 0.01663  -0.00038 204 ARG A O   
2870 C  CB  A ARG A 181 ? 0.14388 0.12261 0.20406 0.00130  0.01928  0.01331  204 ARG A CB  
2871 C  CB  B ARG A 181 ? 0.19866 0.15348 0.19656 0.00810  0.01941  0.00298  204 ARG A CB  
2872 C  CG  A ARG A 181 ? 0.15490 0.12458 0.22813 -0.00086 0.03560  0.00873  204 ARG A CG  
2873 C  CG  B ARG A 181 ? 0.24069 0.17412 0.20871 0.01591  0.02335  0.00142  204 ARG A CG  
2874 C  CD  A ARG A 181 ? 0.18017 0.15391 0.24626 -0.01575 0.02711  0.00337  204 ARG A CD  
2875 C  CD  B ARG A 181 ? 0.28502 0.20068 0.21708 0.01613  0.01807  0.00122  204 ARG A CD  
2876 N  NE  A ARG A 181 ? 0.21536 0.13812 0.26235 -0.01452 0.01770  -0.00041 204 ARG A NE  
2877 N  NE  B ARG A 181 ? 0.32015 0.20351 0.22538 0.02194  0.01278  -0.00134 204 ARG A NE  
2878 C  CZ  A ARG A 181 ? 0.23833 0.17349 0.27937 -0.02452 0.01114  0.00080  204 ARG A CZ  
2879 C  CZ  B ARG A 181 ? 0.35012 0.21374 0.23424 0.01531  0.01148  -0.01407 204 ARG A CZ  
2880 N  NH1 A ARG A 181 ? 0.24886 0.21720 0.28539 -0.02099 0.00784  0.01035  204 ARG A NH1 
2881 N  NH1 B ARG A 181 ? 0.36233 0.19824 0.23915 0.01079  0.01123  -0.02693 204 ARG A NH1 
2882 N  NH2 A ARG A 181 ? 0.24657 0.18175 0.28777 -0.05758 0.00757  0.00835  204 ARG A NH2 
2883 N  NH2 B ARG A 181 ? 0.35779 0.22145 0.23605 0.00623  0.01279  -0.01052 204 ARG A NH2 
2910 N  N   . ALA A 182 ? 0.14201 0.12603 0.20331 -0.01977 0.01748  0.00825  205 ALA A N   
2911 C  CA  . ALA A 182 ? 0.14943 0.13301 0.21104 -0.03685 0.01762  0.01976  205 ALA A CA  
2912 C  C   . ALA A 182 ? 0.15086 0.13578 0.20175 0.00038  0.02186  0.00706  205 ALA A C   
2913 O  O   . ALA A 182 ? 0.15395 0.13802 0.19772 -0.01434 0.00148  0.00564  205 ALA A O   
2914 C  CB  . ALA A 182 ? 0.16708 0.15500 0.22501 -0.01834 0.01014  0.02819  205 ALA A CB  
2920 N  N   . GLN A 183 ? 0.15606 0.12055 0.19767 -0.00574 0.03017  0.00810  206 GLN A N   
2921 C  CA  . GLN A 183 ? 0.13274 0.13394 0.18865 -0.01059 0.02384  0.00913  206 GLN A CA  
2922 C  C   . GLN A 183 ? 0.12925 0.13004 0.17766 -0.01689 0.02802  -0.00344 206 GLN A C   
2923 O  O   . GLN A 183 ? 0.15211 0.13301 0.17979 0.00024  0.01253  0.00748  206 GLN A O   
2924 C  CB  . GLN A 183 ? 0.16663 0.13978 0.19243 -0.01002 0.03739  -0.00119 206 GLN A CB  
2925 C  CG  . GLN A 183 ? 0.16112 0.11790 0.19413 -0.00085 0.03087  0.00175  206 GLN A CG  
2926 C  CD  . GLN A 183 ? 0.16335 0.13723 0.20461 -0.00824 0.04035  0.01188  206 GLN A CD  
2927 O  OE1 . GLN A 183 ? 0.17793 0.18050 0.22581 0.01469  0.05003  0.02300  206 GLN A OE1 
2928 N  NE2 . GLN A 183 ? 0.16365 0.15347 0.19499 0.00382  0.02219  0.00708  206 GLN A NE2 
2937 N  N   . LEU A 184 ? 0.11780 0.13968 0.16587 -0.00420 0.01403  0.00389  207 LEU A N   
2938 C  CA  . LEU A 184 ? 0.13963 0.13464 0.15646 -0.00705 0.01700  0.00161  207 LEU A CA  
2939 C  C   . LEU A 184 ? 0.13346 0.13516 0.15666 -0.00833 0.01440  -0.00696 207 LEU A C   
2940 O  O   . LEU A 184 ? 0.13971 0.16486 0.15004 -0.02091 0.00319  -0.00546 207 LEU A O   
2941 C  CB  . LEU A 184 ? 0.12726 0.14539 0.15165 -0.01590 0.02022  -0.00086 207 LEU A CB  
2942 C  CG  . LEU A 184 ? 0.13440 0.13953 0.14862 0.00124  0.01793  0.00164  207 LEU A CG  
2943 C  CD1 . LEU A 184 ? 0.16545 0.13761 0.16009 -0.01729 0.01546  0.00193  207 LEU A CD1 
2944 C  CD2 . LEU A 184 ? 0.14460 0.14586 0.15622 -0.01083 0.01843  0.01650  207 LEU A CD2 
2956 N  N   . VAL A 185 ? 0.15422 0.13420 0.17203 -0.00897 0.00273  -0.01743 208 VAL A N   
2957 C  CA  . VAL A 185 ? 0.17337 0.13818 0.19087 -0.00685 -0.01364 -0.01546 208 VAL A CA  
2958 C  C   . VAL A 185 ? 0.16174 0.13183 0.19746 0.00282  -0.01556 -0.01421 208 VAL A C   
2959 O  O   . VAL A 185 ? 0.17868 0.16539 0.19106 -0.00619 -0.02636 -0.02296 208 VAL A O   
2960 C  CB  . VAL A 185 ? 0.20436 0.14191 0.20662 0.00643  -0.02976 -0.03198 208 VAL A CB  
2961 C  CG1 . VAL A 185 ? 0.25284 0.16934 0.21621 0.00214  -0.03599 -0.02611 208 VAL A CG1 
2962 C  CG2 . VAL A 185 ? 0.22712 0.17533 0.21033 0.02978  -0.02223 -0.03392 208 VAL A CG2 
2972 N  N   . THR A 186 ? 0.14663 0.14422 0.21056 -0.00617 -0.01770 -0.00732 209 THR A N   
2973 C  CA  . THR A 186 ? 0.15518 0.16254 0.22537 -0.01241 -0.00134 0.01491  209 THR A CA  
2974 C  C   . THR A 186 ? 0.13907 0.14886 0.19904 0.00398  0.00280  -0.01232 209 THR A C   
2975 O  O   . THR A 186 ? 0.15725 0.17223 0.20245 0.00029  -0.02094 -0.00004 209 THR A O   
2976 C  CB  . THR A 186 ? 0.15520 0.20177 0.25876 -0.03826 0.00061  0.05361  209 THR A CB  
2977 O  OG1 . THR A 186 ? 0.19779 0.26121 0.28771 -0.03434 -0.00490 0.07549  209 THR A OG1 
2978 C  CG2 . THR A 186 ? 0.16898 0.24756 0.26967 -0.01605 0.00711  0.05024  209 THR A CG2 
2986 N  N   . TRP A 187 ? 0.14519 0.14845 0.17949 -0.00138 -0.01146 -0.01639 210 TRP A N   
2987 C  CA  . TRP A 187 ? 0.14470 0.15234 0.16387 0.00700  -0.00728 -0.01570 210 TRP A CA  
2988 C  C   . TRP A 187 ? 0.14287 0.16926 0.15708 -0.01003 -0.00293 -0.01164 210 TRP A C   
2989 O  O   . TRP A 187 ? 0.15423 0.16048 0.15874 0.00434  -0.01649 -0.00257 210 TRP A O   
2990 C  CB  . TRP A 187 ? 0.15426 0.16358 0.15918 -0.00987 0.00722  -0.00867 210 TRP A CB  
2991 C  CG  . TRP A 187 ? 0.16435 0.14185 0.16972 0.00776  0.01563  0.01227  210 TRP A CG  
2992 C  CD1 . TRP A 187 ? 0.18536 0.14081 0.18109 0.00341  0.01860  0.00315  210 TRP A CD1 
2993 C  CD2 . TRP A 187 ? 0.16665 0.12844 0.16759 0.00151  0.02866  0.01494  210 TRP A CD2 
2994 N  NE1 . TRP A 187 ? 0.20053 0.14930 0.18790 0.02973  0.02853  0.00558  210 TRP A NE1 
2995 C  CE2 . TRP A 187 ? 0.20200 0.12299 0.17734 -0.00600 0.02780  0.01902  210 TRP A CE2 
2996 C  CE3 . TRP A 187 ? 0.19939 0.12270 0.16088 -0.01335 0.02720  0.01487  210 TRP A CE3 
2997 C  CZ2 . TRP A 187 ? 0.22544 0.12747 0.17315 -0.01157 0.03024  0.01213  210 TRP A CZ2 
2998 C  CZ3 . TRP A 187 ? 0.21746 0.11809 0.17062 -0.01551 0.01891  0.00436  210 TRP A CZ3 
2999 C  CH2 . TRP A 187 ? 0.22482 0.12592 0.16856 -0.01780 0.02362  0.00219  210 TRP A CH2 
3010 N  N   . MET A 188 ? 0.14880 0.14467 0.15462 -0.01462 0.00410  -0.01099 211 MET A N   
3011 C  CA  . MET A 188 ? 0.14224 0.15228 0.14895 -0.01294 0.00109  -0.01562 211 MET A CA  
3012 C  C   . MET A 188 ? 0.15855 0.15728 0.16480 -0.00756 -0.00270 -0.02270 211 MET A C   
3013 O  O   . MET A 188 ? 0.14180 0.16531 0.16585 0.00583  -0.01228 -0.01580 211 MET A O   
3014 C  CB  . MET A 188 ? 0.14679 0.15214 0.13683 -0.01828 -0.00687 -0.01814 211 MET A CB  
3015 C  CG  . MET A 188 ? 0.15306 0.15119 0.13591 -0.02235 0.00305  -0.00691 211 MET A CG  
3016 S  SD  . MET A 188 ? 0.14933 0.15165 0.12386 -0.01134 0.00094  0.00969  211 MET A SD  
3017 C  CE  . MET A 188 ? 0.11496 0.16739 0.13450 0.00694  0.00093  0.00810  211 MET A CE  
3027 N  N   . LYS A 189 ? 0.14336 0.16240 0.18112 -0.02336 -0.02024 -0.03208 212 LYS A N   
3028 C  CA  . LYS A 189 ? 0.14529 0.16373 0.20160 -0.00764 -0.03136 -0.02750 212 LYS A CA  
3029 C  C   . LYS A 189 ? 0.16154 0.17721 0.20147 -0.01548 -0.03886 -0.03636 212 LYS A C   
3030 O  O   . LYS A 189 ? 0.18561 0.19777 0.20347 -0.00106 -0.05694 -0.05674 212 LYS A O   
3031 C  CB  . LYS A 189 ? 0.18044 0.17406 0.23217 -0.03864 -0.02670 -0.02402 212 LYS A CB  
3032 C  CG  . LYS A 189 ? 0.23863 0.16163 0.25924 -0.04321 -0.03481 -0.01263 212 LYS A CG  
3033 C  CD  . LYS A 189 ? 0.31410 0.21263 0.29504 -0.05695 -0.03677 0.00187  212 LYS A CD  
3034 C  CE  . LYS A 189 ? 0.37777 0.27507 0.31717 -0.07024 -0.02107 0.01676  212 LYS A CE  
3035 N  NZ  . LYS A 189 ? 0.40456 0.29114 0.33443 -0.10282 -0.01029 0.03395  212 LYS A NZ  
3049 N  N   . GLY A 190 ? 0.14117 0.18299 0.19747 0.00167  -0.03641 -0.02725 213 GLY A N   
3050 C  CA  . GLY A 190 ? 0.14353 0.19994 0.19983 -0.01121 -0.03000 -0.03505 213 GLY A CA  
3051 C  C   . GLY A 190 ? 0.15021 0.19357 0.19585 0.00125  -0.03302 -0.03040 213 GLY A C   
3052 O  O   . GLY A 190 ? 0.19027 0.18080 0.20193 0.00563  -0.02555 -0.03076 213 GLY A O   
3056 N  N   . ASN A 191 ? 0.16621 0.16835 0.18617 0.00187  -0.04509 -0.02965 214 ASN A N   
3057 C  CA  . ASN A 191 ? 0.15469 0.15801 0.17739 -0.00410 -0.03834 -0.02920 214 ASN A CA  
3058 C  C   . ASN A 191 ? 0.16626 0.17362 0.18643 -0.03730 -0.03875 -0.03084 214 ASN A C   
3059 O  O   . ASN A 191 ? 0.19031 0.18679 0.18631 -0.01639 -0.03305 -0.03967 214 ASN A O   
3060 C  CB  . ASN A 191 ? 0.16684 0.16402 0.17048 -0.01724 -0.02935 -0.00782 214 ASN A CB  
3061 C  CG  . ASN A 191 ? 0.18832 0.13837 0.16004 -0.00195 -0.02707 -0.00767 214 ASN A CG  
3062 O  OD1 . ASN A 191 ? 0.19540 0.15025 0.16514 -0.00364 -0.03640 -0.01026 214 ASN A OD1 
3063 N  ND2 . ASN A 191 ? 0.18493 0.16176 0.15339 0.00799  -0.02035 0.00387  214 ASN A ND2 
3070 N  N   . THR A 192 ? 0.18671 0.14761 0.18342 -0.00106 -0.05002 -0.02407 215 THR A N   
3071 C  CA  . THR A 192 ? 0.21605 0.17860 0.18712 0.00721  -0.07590 -0.01225 215 THR A CA  
3072 C  C   . THR A 192 ? 0.23610 0.15667 0.17749 0.01614  -0.06783 -0.00710 215 THR A C   
3073 O  O   . THR A 192 ? 0.26039 0.21240 0.18142 0.02223  -0.06594 -0.02714 215 THR A O   
3074 C  CB  . THR A 192 ? 0.22285 0.19624 0.18360 0.01703  -0.07622 -0.02103 215 THR A CB  
3075 O  OG1 . THR A 192 ? 0.24366 0.19146 0.17313 0.02511  -0.07055 -0.01658 215 THR A OG1 
3076 C  CG2 . THR A 192 ? 0.23281 0.22998 0.19703 0.03037  -0.06438 -0.03516 215 THR A CG2 
3084 N  N   . THR A 193 ? 0.21786 0.14214 0.17382 0.01684  -0.04658 -0.00946 216 THR A N   
3085 C  CA  . THR A 193 ? 0.22194 0.15250 0.16164 0.01382  -0.04015 -0.01642 216 THR A CA  
3086 C  C   . THR A 193 ? 0.23401 0.17498 0.14471 0.01241  -0.04748 -0.01504 216 THR A C   
3087 O  O   . THR A 193 ? 0.23574 0.17404 0.16186 0.00488  -0.03123 -0.00831 216 THR A O   
3088 C  CB  . THR A 193 ? 0.19831 0.14330 0.15654 0.01998  -0.03770 -0.00496 216 THR A CB  
3089 O  OG1 . THR A 193 ? 0.22265 0.16164 0.14043 -0.00280 -0.01748 -0.00206 216 THR A OG1 
3090 C  CG2 . THR A 193 ? 0.22666 0.18666 0.17244 -0.00068 -0.01625 -0.01321 216 THR A CG2 
3098 N  N   . GLY A 194 ? 0.23559 0.13384 0.12485 0.02277  -0.04688 -0.00966 217 GLY A N   
3099 C  CA  . GLY A 194 ? 0.22513 0.15691 0.12542 0.01949  -0.05391 -0.00533 217 GLY A CA  
3100 C  C   . GLY A 194 ? 0.19135 0.13561 0.11361 -0.00028 -0.03059 0.01470  217 GLY A C   
3101 O  O   . GLY A 194 ? 0.18917 0.13806 0.10835 0.00081  -0.02901 0.00929  217 GLY A O   
3105 N  N   . ALA A 195 ? 0.19577 0.13810 0.10713 0.00172  -0.02372 0.00756  218 ALA A N   
3106 C  CA  . ALA A 195 ? 0.18136 0.14628 0.11122 -0.00607 -0.02170 -0.00473 218 ALA A CA  
3107 C  C   . ALA A 195 ? 0.19099 0.13424 0.11038 -0.00010 -0.03972 -0.00405 218 ALA A C   
3108 O  O   . ALA A 195 ? 0.17717 0.14013 0.13683 -0.01129 -0.00911 -0.01237 218 ALA A O   
3109 C  CB  . ALA A 195 ? 0.18330 0.16467 0.11940 -0.00970 -0.01566 -0.01326 218 ALA A CB  
3115 N  N   . ALA A 196 ? 0.16832 0.13129 0.11552 -0.00532 -0.02896 0.00713  219 ALA A N   
3116 C  CA  . ALA A 196 ? 0.16543 0.13347 0.12091 -0.00929 -0.01066 0.00757  219 ALA A CA  
3117 C  C   . ALA A 196 ? 0.15350 0.16044 0.11821 -0.01608 -0.02103 0.00242  219 ALA A C   
3118 O  O   . ALA A 196 ? 0.17823 0.16420 0.11225 0.00652  -0.02388 0.02302  219 ALA A O   
3119 C  CB  . ALA A 196 ? 0.16852 0.15270 0.13418 -0.00450 -0.02957 0.02463  219 ALA A CB  
3125 N  N   . SER A 197 ? 0.16967 0.13531 0.10586 -0.01975 -0.02493 0.01366  220 SER A N   
3126 C  CA  . SER A 197 ? 0.16165 0.12832 0.10521 -0.01229 -0.02150 -0.00295 220 SER A CA  
3127 C  C   . SER A 197 ? 0.16929 0.13432 0.10667 -0.02171 -0.02019 0.00174  220 SER A C   
3128 O  O   . SER A 197 ? 0.17173 0.12999 0.10931 -0.01258 -0.01953 -0.00025 220 SER A O   
3129 C  CB  . SER A 197 ? 0.16998 0.12009 0.10971 -0.00197 -0.01798 0.00018  220 SER A CB  
3130 O  OG  . SER A 197 ? 0.20632 0.12561 0.11760 -0.00010 -0.02291 0.01134  220 SER A OG  
3136 N  N   . ILE A 198 ? 0.18013 0.11556 0.10117 -0.00211 -0.02832 -0.00130 221 ILE A N   
3137 C  CA  . ILE A 198 ? 0.17044 0.12280 0.10115 -0.01413 -0.02784 -0.00062 221 ILE A CA  
3138 C  C   . ILE A 198 ? 0.17346 0.11930 0.11088 -0.00045 -0.03031 0.00616  221 ILE A C   
3139 O  O   . ILE A 198 ? 0.18857 0.13122 0.11294 -0.00400 -0.02116 -0.00158 221 ILE A O   
3140 C  CB  . ILE A 198 ? 0.17664 0.12504 0.10036 -0.00053 -0.00942 -0.00126 221 ILE A CB  
3141 C  CG1 . ILE A 198 ? 0.18453 0.11541 0.10484 -0.01884 -0.01169 0.00585  221 ILE A CG1 
3142 C  CG2 . ILE A 198 ? 0.17001 0.11108 0.11340 -0.00561 -0.01501 0.01114  221 ILE A CG2 
3143 C  CD1 . ILE A 198 ? 0.17731 0.12277 0.10059 -0.00534 -0.02403 0.00998  221 ILE A CD1 
3155 N  N   A GLN A 199 ? 0.18508 0.11278 0.11762 -0.00409 -0.03518 0.00356  222 GLN A N   
3156 N  N   B GLN A 199 ? 0.17826 0.13085 0.11756 -0.00345 -0.02954 -0.00654 222 GLN A N   
3157 C  CA  A GLN A 199 ? 0.17372 0.13525 0.11983 -0.01531 -0.01378 -0.00312 222 GLN A CA  
3158 C  CA  B GLN A 199 ? 0.17806 0.15009 0.12364 -0.00552 -0.02442 -0.01927 222 GLN A CA  
3159 C  C   A GLN A 199 ? 0.18539 0.14018 0.12232 -0.00636 -0.02959 -0.01164 222 GLN A C   
3160 C  C   B GLN A 199 ? 0.18082 0.15106 0.12027 0.00348  -0.02706 -0.01531 222 GLN A C   
3161 O  O   A GLN A 199 ? 0.18298 0.15578 0.13205 -0.03002 -0.03297 -0.00756 222 GLN A O   
3162 O  O   B GLN A 199 ? 0.17821 0.15495 0.12076 0.00445  -0.02801 -0.01430 222 GLN A O   
3163 C  CB  A GLN A 199 ? 0.20008 0.16275 0.12895 -0.02641 -0.01479 -0.00651 222 GLN A CB  
3164 C  CB  B GLN A 199 ? 0.17955 0.16808 0.13473 -0.01512 -0.02237 -0.03607 222 GLN A CB  
3165 C  CG  A GLN A 199 ? 0.21477 0.16553 0.13944 -0.03671 -0.01568 0.00418  222 GLN A CG  
3166 C  CG  B GLN A 199 ? 0.17409 0.17921 0.14480 -0.02178 -0.02372 -0.04882 222 GLN A CG  
3167 C  CD  A GLN A 199 ? 0.21290 0.20377 0.14478 0.01509  -0.02376 -0.01491 222 GLN A CD  
3168 C  CD  B GLN A 199 ? 0.19465 0.19936 0.15676 -0.02356 -0.01974 -0.06165 222 GLN A CD  
3169 O  OE1 A GLN A 199 ? 0.23024 0.23637 0.15264 -0.01162 -0.03180 -0.02033 222 GLN A OE1 
3170 O  OE1 B GLN A 199 ? 0.21767 0.21811 0.16455 -0.01448 -0.01872 -0.06271 222 GLN A OE1 
3171 N  NE2 A GLN A 199 ? 0.19617 0.21923 0.14251 -0.01569 -0.01540 -0.02340 222 GLN A NE2 
3172 N  NE2 B GLN A 199 ? 0.20108 0.21142 0.15980 -0.02125 -0.01881 -0.07060 222 GLN A NE2 
3189 N  N   . ALA A 200 ? 0.17949 0.14882 0.11712 0.00590  -0.02709 -0.00910 223 ALA A N   
3190 C  CA  . ALA A 200 ? 0.20214 0.15015 0.10992 -0.00629 -0.03845 -0.00013 223 ALA A CA  
3191 C  C   . ALA A 200 ? 0.21567 0.15496 0.11020 0.01032  -0.03750 0.00343  223 ALA A C   
3192 O  O   . ALA A 200 ? 0.25865 0.17939 0.10512 0.03845  -0.04343 -0.01601 223 ALA A O   
3193 C  CB  . ALA A 200 ? 0.21578 0.15424 0.12004 -0.00415 -0.03220 -0.00651 223 ALA A CB  
3199 N  N   . GLY A 201 ? 0.18595 0.14900 0.11828 0.00382  -0.02811 0.00180  224 GLY A N   
3200 C  CA  . GLY A 201 ? 0.18567 0.14964 0.12169 0.00066  -0.02197 0.00361  224 GLY A CA  
3201 C  C   . GLY A 201 ? 0.18838 0.13655 0.12545 0.00765  -0.01969 0.00196  224 GLY A C   
3202 O  O   . GLY A 201 ? 0.20545 0.15354 0.14676 0.00458  0.00073  0.00731  224 GLY A O   
3206 N  N   . LEU A 202 ? 0.18794 0.12839 0.12538 -0.01318 -0.02982 -0.00154 225 LEU A N   
3207 C  CA  . LEU A 202 ? 0.20263 0.12136 0.13285 -0.00380 -0.01956 -0.00020 225 LEU A CA  
3208 C  C   . LEU A 202 ? 0.18804 0.13183 0.13162 -0.00342 -0.02541 0.00087  225 LEU A C   
3209 O  O   . LEU A 202 ? 0.17859 0.14979 0.14413 -0.00959 -0.03940 0.01056  225 LEU A O   
3210 C  CB  . LEU A 202 ? 0.20902 0.14240 0.12766 -0.01405 -0.03156 0.00246  225 LEU A CB  
3211 C  CG  . LEU A 202 ? 0.22155 0.14881 0.12486 -0.01020 -0.03725 0.01360  225 LEU A CG  
3212 C  CD1 . LEU A 202 ? 0.26966 0.14991 0.11966 -0.02022 -0.03074 0.00192  225 LEU A CD1 
3213 C  CD2 . LEU A 202 ? 0.22418 0.17584 0.13872 -0.05043 -0.03370 0.02768  225 LEU A CD2 
3225 N  N   . PRO A 203 ? 0.19078 0.12974 0.14609 -0.00417 -0.03567 0.00930  226 PRO A N   
3226 C  CA  . PRO A 203 ? 0.20826 0.13951 0.14771 0.00505  -0.04325 0.00886  226 PRO A CA  
3227 C  C   . PRO A 203 ? 0.19602 0.13567 0.15572 -0.02764 -0.03699 0.01287  226 PRO A C   
3228 O  O   . PRO A 203 ? 0.20163 0.15530 0.15310 -0.00744 -0.04842 -0.01153 226 PRO A O   
3229 C  CB  . PRO A 203 ? 0.24138 0.15154 0.15794 -0.00834 -0.04449 -0.00251 226 PRO A CB  
3230 C  CG  . PRO A 203 ? 0.25215 0.12588 0.15708 0.00260  -0.04402 0.00031  226 PRO A CG  
3231 C  CD  . PRO A 203 ? 0.19803 0.14160 0.15144 0.00039  -0.03675 0.00380  226 PRO A CD  
3239 N  N   . ALA A 204 ? 0.20357 0.15560 0.16090 -0.00817 -0.05150 0.01843  227 ALA A N   
3240 C  CA  . ALA A 204 ? 0.20335 0.19260 0.16457 -0.00849 -0.04606 0.01359  227 ALA A CA  
3241 C  C   . ALA A 204 ? 0.20647 0.20660 0.16626 0.01032  -0.05195 0.01442  227 ALA A C   
3242 O  O   . ALA A 204 ? 0.23541 0.24873 0.18376 0.02481  -0.02914 0.00314  227 ALA A O   
3243 C  CB  . ALA A 204 ? 0.18714 0.22836 0.16673 0.01825  -0.03003 0.03003  227 ALA A CB  
3249 N  N   . SER A 205 ? 0.21037 0.21101 0.16195 -0.03152 -0.04677 0.01974  228 SER A N   
3250 C  CA  . SER A 205 ? 0.23739 0.24525 0.16225 -0.05135 -0.03921 0.02252  228 SER A CA  
3251 C  C   . SER A 205 ? 0.24461 0.24722 0.15217 -0.05517 -0.03269 0.01087  228 SER A C   
3252 O  O   . SER A 205 ? 0.28493 0.30284 0.15671 -0.05817 -0.02359 0.01128  228 SER A O   
3253 C  CB  . SER A 205 ? 0.26339 0.24009 0.17192 -0.08665 -0.04526 0.01764  228 SER A CB  
3254 O  OG  . SER A 205 ? 0.28117 0.22186 0.18105 -0.08543 -0.05209 0.02231  228 SER A OG  
3260 N  N   . TRP A 206 ? 0.23096 0.17894 0.14519 -0.02752 -0.04682 0.00600  229 TRP A N   
3261 C  CA  . TRP A 206 ? 0.23969 0.15198 0.14865 -0.02139 -0.04856 0.00726  229 TRP A CA  
3262 C  C   . TRP A 206 ? 0.27890 0.14873 0.15553 -0.00327 -0.02997 0.01242  229 TRP A C   
3263 O  O   . TRP A 206 ? 0.33094 0.16245 0.16211 0.01391  -0.00801 0.02403  229 TRP A O   
3264 C  CB  . TRP A 206 ? 0.26025 0.13823 0.14495 -0.00236 -0.05345 0.00559  229 TRP A CB  
3265 C  CG  . TRP A 206 ? 0.26366 0.11971 0.14151 -0.00780 -0.05014 0.01017  229 TRP A CG  
3266 C  CD1 . TRP A 206 ? 0.27108 0.15039 0.15880 -0.00401 -0.04514 0.00822  229 TRP A CD1 
3267 C  CD2 . TRP A 206 ? 0.25206 0.15934 0.14379 0.00407  -0.04571 0.00865  229 TRP A CD2 
3268 N  NE1 . TRP A 206 ? 0.27704 0.16528 0.16304 -0.00771 -0.05149 0.00567  229 TRP A NE1 
3269 C  CE2 . TRP A 206 ? 0.26671 0.14413 0.16429 0.01152  -0.04412 0.00459  229 TRP A CE2 
3270 C  CE3 . TRP A 206 ? 0.24503 0.15607 0.14702 -0.01008 -0.03590 0.02533  229 TRP A CE3 
3271 C  CZ2 . TRP A 206 ? 0.28459 0.16472 0.17265 0.01866  -0.03731 -0.00695 229 TRP A CZ2 
3272 C  CZ3 . TRP A 206 ? 0.26213 0.18209 0.16327 -0.00622 -0.03710 0.01973  229 TRP A CZ3 
3273 C  CH2 . TRP A 206 ? 0.25037 0.18807 0.17085 0.02162  -0.02886 0.00392  229 TRP A CH2 
3284 N  N   . VAL A 207 ? 0.25072 0.13697 0.15749 -0.02482 -0.03197 0.00104  230 VAL A N   
3285 C  CA  . VAL A 207 ? 0.20894 0.16398 0.17102 -0.00781 -0.03891 -0.00736 230 VAL A CA  
3286 C  C   . VAL A 207 ? 0.18440 0.13341 0.16254 -0.00001 -0.03945 -0.00546 230 VAL A C   
3287 O  O   . VAL A 207 ? 0.17630 0.13649 0.16929 -0.01112 -0.05019 0.00727  230 VAL A O   
3288 C  CB  . VAL A 207 ? 0.23479 0.18787 0.18630 -0.03123 -0.02013 -0.02523 230 VAL A CB  
3289 C  CG1 . VAL A 207 ? 0.24896 0.21384 0.19817 -0.04405 -0.01678 -0.03390 230 VAL A CG1 
3290 C  CG2 . VAL A 207 ? 0.28316 0.22479 0.20014 -0.04598 -0.01121 -0.02664 230 VAL A CG2 
3300 N  N   . VAL A 208 ? 0.15950 0.13719 0.16336 0.00608  -0.03886 -0.01266 231 VAL A N   
3301 C  CA  . VAL A 208 ? 0.18016 0.13692 0.16424 -0.00246 -0.03221 -0.00225 231 VAL A CA  
3302 C  C   . VAL A 208 ? 0.14907 0.13120 0.15649 -0.00024 -0.02377 0.00110  231 VAL A C   
3303 O  O   . VAL A 208 ? 0.16609 0.15735 0.17183 0.02078  -0.04245 -0.02165 231 VAL A O   
3304 C  CB  . VAL A 208 ? 0.19606 0.17749 0.16453 -0.00912 -0.02243 -0.00663 231 VAL A CB  
3305 C  CG1 . VAL A 208 ? 0.21160 0.20366 0.16732 -0.04126 -0.02287 0.00267  231 VAL A CG1 
3306 C  CG2 . VAL A 208 ? 0.22103 0.19188 0.16947 0.02103  -0.00941 -0.01103 231 VAL A CG2 
3316 N  N   . GLY A 209 ? 0.14499 0.11277 0.14097 -0.00814 -0.01421 0.00981  232 GLY A N   
3317 C  CA  . GLY A 209 ? 0.13946 0.12107 0.14424 0.00048  -0.00744 0.00613  232 GLY A CA  
3318 C  C   . GLY A 209 ? 0.14434 0.10874 0.13762 -0.00540 -0.00497 0.00843  232 GLY A C   
3319 O  O   . GLY A 209 ? 0.14416 0.13554 0.17459 0.00514  0.00371  0.02413  232 GLY A O   
3323 N  N   . ASP A 210 ? 0.14527 0.10580 0.12873 -0.00942 -0.00978 0.00663  233 ASP A N   
3324 C  CA  . ASP A 210 ? 0.15571 0.10557 0.11679 -0.00556 -0.00105 0.00132  233 ASP A CA  
3325 C  C   . ASP A 210 ? 0.12071 0.10737 0.11272 0.00104  -0.01650 0.00638  233 ASP A C   
3326 O  O   . ASP A 210 ? 0.12949 0.11891 0.13497 0.00266  -0.01881 -0.00622 233 ASP A O   
3327 C  CB  . ASP A 210 ? 0.15235 0.12259 0.11666 -0.01480 -0.00040 0.00581  233 ASP A CB  
3328 C  CG  . ASP A 210 ? 0.13693 0.12605 0.11776 -0.01745 -0.01141 -0.00473 233 ASP A CG  
3329 O  OD1 . ASP A 210 ? 0.17091 0.13742 0.13354 -0.00721 -0.01473 0.00475  233 ASP A OD1 
3330 O  OD2 . ASP A 210 ? 0.14800 0.12542 0.10701 -0.01449 -0.00608 0.00367  233 ASP A OD2 
3335 N  N   . LYS A 211 ? 0.13532 0.10244 0.10415 -0.00546 0.00065  -0.00590 234 LYS A N   
3336 C  CA  . LYS A 211 ? 0.15325 0.10608 0.10641 -0.00496 -0.00729 -0.00244 234 LYS A CA  
3337 C  C   . LYS A 211 ? 0.14323 0.09278 0.10262 0.00673  -0.00384 -0.00430 234 LYS A C   
3338 O  O   . LYS A 211 ? 0.14883 0.11494 0.09826 -0.00293 -0.00801 0.00743  234 LYS A O   
3339 C  CB  . LYS A 211 ? 0.17130 0.11529 0.10950 -0.01767 0.00052  -0.00642 234 LYS A CB  
3340 C  CG  . LYS A 211 ? 0.17421 0.11206 0.11759 -0.01564 0.00541  -0.00717 234 LYS A CG  
3341 C  CD  . LYS A 211 ? 0.18852 0.10785 0.14052 -0.00017 0.01867  -0.00953 234 LYS A CD  
3342 C  CE  . LYS A 211 ? 0.17784 0.12931 0.14597 0.00467  0.00572  -0.00862 234 LYS A CE  
3343 N  NZ  . LYS A 211 ? 0.17420 0.11797 0.15236 -0.01058 -0.01330 -0.01145 234 LYS A NZ  
3357 N  N   . THR A 212 ? 0.13310 0.09999 0.11138 -0.00052 -0.00580 0.01624  235 THR A N   
3358 C  CA  . THR A 212 ? 0.14417 0.11733 0.10970 0.00083  -0.01472 0.01419  235 THR A CA  
3359 C  C   . THR A 212 ? 0.15019 0.11634 0.10756 -0.00142 -0.00444 0.00341  235 THR A C   
3360 O  O   . THR A 212 ? 0.16361 0.11550 0.11704 -0.00224 0.00079  -0.00204 235 THR A O   
3361 C  CB  . THR A 212 ? 0.14586 0.14136 0.12896 -0.00408 -0.02522 0.01548  235 THR A CB  
3362 O  OG1 . THR A 212 ? 0.19259 0.15158 0.15448 0.02014  -0.03782 0.02042  235 THR A OG1 
3363 C  CG2 . THR A 212 ? 0.18815 0.15525 0.12300 -0.04531 -0.03126 0.01767  235 THR A CG2 
3371 N  N   . GLY A 213 ? 0.15783 0.12090 0.10718 -0.01112 0.00152  -0.00014 236 GLY A N   
3372 C  CA  . GLY A 213 ? 0.16207 0.11643 0.11493 -0.01337 0.01095  0.01002  236 GLY A CA  
3373 C  C   . GLY A 213 ? 0.18248 0.12050 0.12223 0.00210  0.02413  0.00428  236 GLY A C   
3374 O  O   . GLY A 213 ? 0.19900 0.12341 0.12923 0.00687  0.02878  0.00228  236 GLY A O   
3378 N  N   A SER A 214 ? 0.18376 0.11100 0.12517 -0.00031 0.03466  0.00623  237 SER A N   
3379 N  N   B SER A 214 ? 0.19057 0.12402 0.12456 -0.01401 0.02410  0.00285  237 SER A N   
3380 N  N   C SER A 214 ? 0.18927 0.12746 0.12099 -0.00253 0.02620  0.00366  237 SER A N   
3381 C  CA  A SER A 214 ? 0.18502 0.14388 0.14072 -0.00313 0.02748  0.02366  237 SER A CA  
3382 C  CA  B SER A 214 ? 0.19590 0.13601 0.13274 -0.02363 0.01795  0.00465  237 SER A CA  
3383 C  CA  C SER A 214 ? 0.19626 0.14174 0.12446 -0.00579 0.02245  0.00572  237 SER A CA  
3384 C  C   A SER A 214 ? 0.19129 0.11886 0.12723 -0.01929 0.02035  0.01492  237 SER A C   
3385 C  C   B SER A 214 ? 0.19150 0.12301 0.12386 -0.03117 0.01601  0.00193  237 SER A C   
3386 C  C   C SER A 214 ? 0.19198 0.12725 0.12078 -0.02324 0.01817  0.00409  237 SER A C   
3387 O  O   A SER A 214 ? 0.19577 0.13366 0.13223 0.00603  0.03078  0.00702  237 SER A O   
3388 O  O   B SER A 214 ? 0.19003 0.13059 0.12456 -0.02929 0.02002  -0.00785 237 SER A O   
3389 O  O   C SER A 214 ? 0.19238 0.13567 0.12237 -0.02426 0.02079  -0.00208 237 SER A O   
3390 C  CB  A SER A 214 ? 0.22221 0.20165 0.16833 -0.04052 -0.00216 0.02898  237 SER A CB  
3391 C  CB  B SER A 214 ? 0.22136 0.15044 0.14966 -0.04330 0.00166  -0.00111 237 SER A CB  
3392 C  CB  C SER A 214 ? 0.22235 0.16533 0.13127 -0.00405 0.01350  0.00090  237 SER A CB  
3393 O  OG  A SER A 214 ? 0.22223 0.23100 0.18692 -0.01321 -0.01799 0.04119  237 SER A OG  
3394 O  OG  B SER A 214 ? 0.23173 0.14365 0.16330 -0.05939 -0.01558 0.00223  237 SER A OG  
3395 O  OG  C SER A 214 ? 0.23640 0.17597 0.13511 0.00440  0.00424  0.00346  237 SER A OG  
3411 N  N   . GLY A 215 ? 0.18187 0.11495 0.12018 -0.02460 0.01774  0.00502  238 GLY A N   
3412 C  CA  . GLY A 215 ? 0.18634 0.13411 0.11823 -0.01984 0.01904  0.00896  238 GLY A CA  
3413 C  C   . GLY A 215 ? 0.20102 0.10790 0.11135 -0.02446 0.01424  0.00714  238 GLY A C   
3414 O  O   . GLY A 215 ? 0.22103 0.13839 0.10482 -0.03226 0.01342  0.00629  238 GLY A O   
3418 N  N   . GLY A 216 ? 0.20013 0.13374 0.11577 -0.02146 0.01693  -0.00102 239 GLY A N   
3419 C  CA  . GLY A 216 ? 0.19895 0.13749 0.12428 -0.01911 0.01928  0.01483  239 GLY A CA  
3420 C  C   . GLY A 216 ? 0.20609 0.12788 0.10801 -0.03245 0.02014  0.00672  239 GLY A C   
3421 O  O   . GLY A 216 ? 0.20808 0.14204 0.09877 -0.02555 0.01738  0.00309  239 GLY A O   
3425 N  N   . TYR A 217 ? 0.22246 0.14739 0.11661 -0.03114 0.02099  0.00060  240 TYR A N   
3426 C  CA  . TYR A 217 ? 0.18804 0.14842 0.11814 -0.01716 0.02783  0.00459  240 TYR A CA  
3427 C  C   . TYR A 217 ? 0.17799 0.13744 0.10603 -0.03534 0.03378  0.00043  240 TYR A C   
3428 O  O   . TYR A 217 ? 0.21014 0.13871 0.11516 -0.03041 0.02780  0.00323  240 TYR A O   
3429 C  CB  . TYR A 217 ? 0.17404 0.16193 0.12143 -0.03401 0.03106  -0.00501 240 TYR A CB  
3430 C  CG  . TYR A 217 ? 0.18753 0.18278 0.12696 -0.04588 0.01597  0.00985  240 TYR A CG  
3431 C  CD1 . TYR A 217 ? 0.18942 0.19452 0.14118 -0.04776 0.01604  0.01011  240 TYR A CD1 
3432 C  CD2 . TYR A 217 ? 0.18958 0.19266 0.13697 -0.04893 0.02935  0.01545  240 TYR A CD2 
3433 C  CE1 . TYR A 217 ? 0.21627 0.18660 0.15214 -0.05128 0.01325  0.00547  240 TYR A CE1 
3434 C  CE2 . TYR A 217 ? 0.19530 0.19222 0.14700 -0.04687 0.02837  0.02868  240 TYR A CE2 
3435 C  CZ  . TYR A 217 ? 0.21912 0.19331 0.16659 -0.07537 0.00526  0.01371  240 TYR A CZ  
3436 O  OH  . TYR A 217 ? 0.26336 0.24318 0.19769 -0.08779 0.00965  0.02535  240 TYR A OH  
3446 N  N   . GLY A 218 ? 0.19841 0.13888 0.10942 -0.01993 0.02820  0.00146  241 GLY A N   
3447 C  CA  . GLY A 218 ? 0.19736 0.13306 0.11598 -0.01810 0.02249  0.00343  241 GLY A CA  
3448 C  C   . GLY A 218 ? 0.20245 0.12700 0.11197 -0.01855 0.02177  -0.00289 241 GLY A C   
3449 O  O   . GLY A 218 ? 0.20852 0.13408 0.10624 -0.01544 0.01654  0.00317  241 GLY A O   
3453 N  N   . THR A 219 ? 0.21158 0.12630 0.10116 -0.03010 0.02724  0.00341  242 THR A N   
3454 C  CA  . THR A 219 ? 0.16961 0.11765 0.10335 -0.01133 0.00365  0.00327  242 THR A CA  
3455 C  C   . THR A 219 ? 0.17157 0.11666 0.09702 -0.00568 0.01260  -0.00765 242 THR A C   
3456 O  O   . THR A 219 ? 0.19372 0.11339 0.11217 -0.01079 0.01429  0.00094  242 THR A O   
3457 C  CB  . THR A 219 ? 0.16800 0.13210 0.09840 -0.02260 0.00763  0.00406  242 THR A CB  
3458 O  OG1 . THR A 219 ? 0.19288 0.14023 0.11277 -0.01689 0.00755  0.00151  242 THR A OG1 
3459 C  CG2 . THR A 219 ? 0.20359 0.14490 0.10460 -0.00337 0.00964  0.00264  242 THR A CG2 
3467 N  N   . THR A 220 ? 0.17468 0.11365 0.09950 -0.01237 0.00987  0.00884  243 THR A N   
3468 C  CA  . THR A 220 ? 0.17043 0.11383 0.10003 -0.00654 0.00904  0.01101  243 THR A CA  
3469 C  C   . THR A 220 ? 0.15960 0.10598 0.10151 -0.00149 0.00606  0.00439  243 THR A C   
3470 O  O   . THR A 220 ? 0.17564 0.11844 0.09465 -0.00376 0.00489  0.00690  243 THR A O   
3471 C  CB  . THR A 220 ? 0.19835 0.13745 0.09670 -0.03657 -0.00650 0.01526  243 THR A CB  
3472 O  OG1 . THR A 220 ? 0.20406 0.14622 0.09946 -0.02773 -0.00881 0.02005  243 THR A OG1 
3473 C  CG2 . THR A 220 ? 0.21436 0.17771 0.10340 -0.04007 -0.01071 0.02069  243 THR A CG2 
3481 N  N   . ASN A 221 ? 0.14333 0.11333 0.09591 0.00464  0.00768  0.00786  244 ASN A N   
3482 C  CA  . ASN A 221 ? 0.14271 0.12659 0.09052 0.00116  -0.00062 0.00850  244 ASN A CA  
3483 C  C   . ASN A 221 ? 0.14818 0.10476 0.08904 -0.00647 -0.00568 0.00494  244 ASN A C   
3484 O  O   . ASN A 221 ? 0.14467 0.10916 0.09536 -0.00165 -0.01084 0.00138  244 ASN A O   
3485 C  CB  . ASN A 221 ? 0.16247 0.13074 0.08540 -0.02924 0.00252  0.00259  244 ASN A CB  
3486 C  CG  . ASN A 221 ? 0.16583 0.11250 0.08984 -0.01490 0.00850  0.00217  244 ASN A CG  
3487 O  OD1 . ASN A 221 ? 0.16918 0.13541 0.09090 -0.01319 0.00819  0.00880  244 ASN A OD1 
3488 N  ND2 . ASN A 221 ? 0.16132 0.12760 0.10089 -0.01985 0.00823  -0.00243 244 ASN A ND2 
3495 N  N   . ASP A 222 ? 0.14356 0.11960 0.09340 -0.00218 -0.01031 0.00633  245 ASP A N   
3496 C  CA  . ASP A 222 ? 0.13893 0.10794 0.10053 -0.00874 -0.00955 0.00664  245 ASP A CA  
3497 C  C   . ASP A 222 ? 0.11421 0.10843 0.10169 0.00220  -0.00186 0.00134  245 ASP A C   
3498 O  O   . ASP A 222 ? 0.14019 0.11492 0.09461 -0.00032 0.00207  0.00737  245 ASP A O   
3499 C  CB  . ASP A 222 ? 0.14748 0.11582 0.09057 -0.01041 -0.01434 0.01169  245 ASP A CB  
3500 C  CG  . ASP A 222 ? 0.16290 0.10479 0.09249 -0.00836 -0.02344 0.00429  245 ASP A CG  
3501 O  OD1 . ASP A 222 ? 0.16360 0.12119 0.09562 -0.00841 -0.00912 -0.00689 245 ASP A OD1 
3502 O  OD2 . ASP A 222 ? 0.14939 0.11873 0.10738 -0.00664 -0.01372 0.00066  245 ASP A OD2 
3507 N  N   . ILE A 223 ? 0.13986 0.09396 0.09584 -0.00053 0.00253  0.00227  246 ILE A N   
3508 C  CA  . ILE A 223 ? 0.12187 0.11094 0.10406 0.00499  -0.01039 0.00832  246 ILE A CA  
3509 C  C   . ILE A 223 ? 0.12760 0.12076 0.10240 0.00321  -0.00898 0.00728  246 ILE A C   
3510 O  O   . ILE A 223 ? 0.12932 0.11412 0.11557 -0.00280 -0.00221 0.00501  246 ILE A O   
3511 C  CB  . ILE A 223 ? 0.13015 0.11379 0.10752 -0.00083 -0.00146 0.01389  246 ILE A CB  
3512 C  CG1 . ILE A 223 ? 0.15484 0.12713 0.10282 -0.00140 0.00653  -0.00002 246 ILE A CG1 
3513 C  CG2 . ILE A 223 ? 0.12891 0.10674 0.10555 0.00081  -0.00184 0.01141  246 ILE A CG2 
3514 C  CD1 . ILE A 223 ? 0.17710 0.13783 0.09739 -0.00458 0.00331  -0.00452 246 ILE A CD1 
3526 N  N   . ALA A 224 ? 0.12451 0.09852 0.10758 0.00343  0.00211  0.00481  247 ALA A N   
3527 C  CA  . ALA A 224 ? 0.13690 0.11339 0.11528 -0.01215 -0.00464 0.00591  247 ALA A CA  
3528 C  C   . ALA A 224 ? 0.12712 0.09587 0.11415 -0.00806 -0.00799 0.00157  247 ALA A C   
3529 O  O   . ALA A 224 ? 0.13745 0.11252 0.11473 -0.00137 0.00084  0.00928  247 ALA A O   
3530 C  CB  . ALA A 224 ? 0.16393 0.11395 0.12470 -0.00982 -0.01280 0.01707  247 ALA A CB  
3536 N  N   . VAL A 225 ? 0.14931 0.10633 0.12454 -0.00020 0.00082  0.00300  248 VAL A N   
3537 C  CA  . VAL A 225 ? 0.13723 0.10966 0.12178 -0.01628 0.00939  0.01300  248 VAL A CA  
3538 C  C   . VAL A 225 ? 0.14772 0.10884 0.12428 -0.00462 -0.01584 0.01873  248 VAL A C   
3539 O  O   . VAL A 225 ? 0.16412 0.11751 0.13726 0.01328  -0.02656 0.00646  248 VAL A O   
3540 C  CB  . VAL A 225 ? 0.14548 0.12626 0.13381 -0.00305 0.00262  0.02347  248 VAL A CB  
3541 C  CG1 . VAL A 225 ? 0.20090 0.15442 0.12616 -0.00578 0.01600  0.00738  248 VAL A CG1 
3542 C  CG2 . VAL A 225 ? 0.15872 0.14263 0.13160 -0.00642 0.00771  0.02738  248 VAL A CG2 
3552 N  N   . ILE A 226 ? 0.15942 0.11270 0.12725 -0.00972 -0.03122 0.01488  249 ILE A N   
3553 C  CA  . ILE A 226 ? 0.17160 0.11489 0.13552 -0.01460 -0.02481 0.01830  249 ILE A CA  
3554 C  C   . ILE A 226 ? 0.18794 0.12156 0.14620 -0.01467 -0.03466 0.01654  249 ILE A C   
3555 O  O   . ILE A 226 ? 0.19678 0.11928 0.16361 -0.01444 -0.03191 0.01880  249 ILE A O   
3556 C  CB  . ILE A 226 ? 0.17655 0.12752 0.14328 -0.00419 -0.00942 0.00551  249 ILE A CB  
3557 C  CG1 . ILE A 226 ? 0.17985 0.13460 0.14405 -0.01850 -0.02685 0.01633  249 ILE A CG1 
3558 C  CG2 . ILE A 226 ? 0.22780 0.12222 0.13631 -0.02070 -0.02145 0.00254  249 ILE A CG2 
3559 C  CD1 . ILE A 226 ? 0.19463 0.15849 0.15371 -0.01469 -0.01910 0.03212  249 ILE A CD1 
3571 N  N   . TRP A 227 ? 0.17754 0.13036 0.16450 -0.01955 -0.02750 0.00973  250 TRP A N   
3572 C  CA  . TRP A 227 ? 0.21647 0.14212 0.17002 -0.04460 -0.03602 0.02473  250 TRP A CA  
3573 C  C   . TRP A 227 ? 0.22231 0.15641 0.17758 -0.03489 -0.05440 0.02205  250 TRP A C   
3574 O  O   . TRP A 227 ? 0.23924 0.16100 0.19535 -0.05269 -0.05848 0.01823  250 TRP A O   
3575 C  CB  . TRP A 227 ? 0.22106 0.19848 0.17347 -0.04477 -0.02142 0.02355  250 TRP A CB  
3576 C  CG  . TRP A 227 ? 0.24053 0.28216 0.19251 -0.03325 -0.00350 0.02206  250 TRP A CG  
3577 C  CD1 . TRP A 227 ? 0.24047 0.30064 0.20249 -0.04207 0.00428  0.02874  250 TRP A CD1 
3578 C  CD2 . TRP A 227 ? 0.23277 0.30723 0.20075 -0.04997 0.00271  0.00386  250 TRP A CD2 
3579 N  NE1 . TRP A 227 ? 0.25407 0.35633 0.21183 -0.01889 0.00334  0.01660  250 TRP A NE1 
3580 C  CE2 . TRP A 227 ? 0.24101 0.33915 0.20880 -0.04648 -0.00013 0.00074  250 TRP A CE2 
3581 C  CE3 . TRP A 227 ? 0.24093 0.30948 0.20895 -0.03339 -0.00032 -0.00826 250 TRP A CE3 
3582 C  CZ2 . TRP A 227 ? 0.23909 0.36424 0.21680 -0.03576 -0.00092 -0.00926 250 TRP A CZ2 
3583 C  CZ3 . TRP A 227 ? 0.24166 0.31892 0.21883 -0.03859 0.00040  -0.01896 250 TRP A CZ3 
3584 C  CH2 . TRP A 227 ? 0.24900 0.33859 0.22184 -0.03232 0.00389  -0.01688 250 TRP A CH2 
3595 N  N   . PRO A 228 ? 0.25032 0.13780 0.17891 -0.02124 -0.05030 0.01748  251 PRO A N   
3596 C  CA  . PRO A 228 ? 0.28115 0.14891 0.17345 -0.02377 -0.05173 0.02074  251 PRO A CA  
3597 C  C   . PRO A 228 ? 0.29318 0.16316 0.18745 -0.04151 -0.06247 0.00459  251 PRO A C   
3598 O  O   . PRO A 228 ? 0.30736 0.16738 0.18661 -0.06804 -0.05124 0.01022  251 PRO A O   
3599 C  CB  . PRO A 228 ? 0.26816 0.17529 0.17284 -0.00390 -0.03592 0.03456  251 PRO A CB  
3600 C  CG  . PRO A 228 ? 0.26485 0.16437 0.18398 -0.00916 -0.03336 0.01767  251 PRO A CG  
3601 C  CD  . PRO A 228 ? 0.25710 0.14913 0.18509 -0.01220 -0.03619 0.01162  251 PRO A CD  
3609 N  N   . LYS A 229 ? 0.28777 0.20310 0.21064 -0.05106 -0.08894 -0.00318 252 LYS A N   
3610 C  CA  . LYS A 229 ? 0.30981 0.21720 0.23731 -0.06361 -0.10805 0.01542  252 LYS A CA  
3611 C  C   . LYS A 229 ? 0.30916 0.19220 0.24670 -0.05011 -0.10780 0.01403  252 LYS A C   
3612 O  O   . LYS A 229 ? 0.35037 0.20835 0.25098 -0.03217 -0.10005 0.00629  252 LYS A O   
3613 C  CB  . LYS A 229 ? 0.36330 0.27043 0.25453 -0.10024 -0.12941 0.02120  252 LYS A CB  
3614 C  CG  . LYS A 229 ? 0.41858 0.33997 0.27598 -0.14215 -0.14399 0.02612  252 LYS A CG  
3615 C  CD  . LYS A 229 ? 0.47623 0.43501 0.29824 -0.15182 -0.15507 0.01336  252 LYS A CD  
3616 C  CE  . LYS A 229 ? 0.53641 0.50296 0.31513 -0.14914 -0.14832 0.00406  252 LYS A CE  
3617 N  NZ  . LYS A 229 ? 0.57012 0.56163 0.32406 -0.13404 -0.14470 0.00934  252 LYS A NZ  
3631 N  N   . ASP A 230 ? 0.29420 0.18034 0.25865 -0.07151 -0.11403 0.03283  253 ASP A N   
3632 C  CA  . ASP A 230 ? 0.30093 0.18817 0.26932 -0.07027 -0.10888 0.01922  253 ASP A CA  
3633 C  C   . ASP A 230 ? 0.31152 0.14906 0.24766 -0.05186 -0.09296 0.00975  253 ASP A C   
3634 O  O   . ASP A 230 ? 0.36338 0.15459 0.26580 -0.06811 -0.09853 0.00684  253 ASP A O   
3635 C  CB  . ASP A 230 ? 0.33458 0.21846 0.29456 -0.08547 -0.10902 0.01994  253 ASP A CB  
3636 C  CG  . ASP A 230 ? 0.37497 0.27920 0.31928 -0.09549 -0.10593 0.02502  253 ASP A CG  
3637 O  OD1 . ASP A 230 ? 0.37259 0.30676 0.33289 -0.08628 -0.08266 0.02480  253 ASP A OD1 
3638 O  OD2 . ASP A 230 ? 0.40968 0.31725 0.33012 -0.08605 -0.12158 0.03656  253 ASP A OD2 
3643 N  N   A ARG A 231 ? 0.28930 0.14505 0.22558 -0.03507 -0.08893 0.00577  254 ARG A N   
3644 N  N   B ARG A 231 ? 0.28250 0.12735 0.22393 -0.05240 -0.09144 0.01617  254 ARG A N   
3645 C  CA  A ARG A 231 ? 0.28546 0.16053 0.20951 -0.02248 -0.07820 -0.00552 254 ARG A CA  
3646 C  CA  B ARG A 231 ? 0.27600 0.13814 0.20769 -0.04626 -0.08244 0.01220  254 ARG A CA  
3647 C  C   A ARG A 231 ? 0.24601 0.13650 0.19212 -0.02146 -0.05948 0.01414  254 ARG A C   
3648 C  C   B ARG A 231 ? 0.23316 0.11910 0.19020 -0.04068 -0.06127 0.02404  254 ARG A C   
3649 O  O   A ARG A 231 ? 0.24403 0.16285 0.18948 -0.01081 -0.05128 0.01700  254 ARG A O   
3650 O  O   B ARG A 231 ? 0.22688 0.13322 0.18601 -0.03694 -0.05126 0.03023  254 ARG A O   
3651 C  CB  A ARG A 231 ? 0.33125 0.20132 0.21642 -0.01346 -0.06353 -0.01799 254 ARG A CB  
3652 C  CB  B ARG A 231 ? 0.32211 0.16822 0.21508 -0.05290 -0.06672 0.01679  254 ARG A CB  
3653 C  CG  A ARG A 231 ? 0.38327 0.25172 0.22385 -0.00619 -0.05296 -0.04262 254 ARG A CG  
3654 C  CG  B ARG A 231 ? 0.37428 0.22460 0.22344 -0.06540 -0.05886 0.00431  254 ARG A CG  
3655 C  CD  A ARG A 231 ? 0.44954 0.29914 0.23211 0.00787  -0.04166 -0.06819 254 ARG A CD  
3656 C  CD  B ARG A 231 ? 0.44848 0.28238 0.23259 -0.06333 -0.04922 -0.00700 254 ARG A CD  
3657 N  NE  A ARG A 231 ? 0.50933 0.34293 0.24261 0.01095  -0.03594 -0.09098 254 ARG A NE  
3658 N  NE  B ARG A 231 ? 0.51204 0.32327 0.24341 -0.06482 -0.04338 -0.01675 254 ARG A NE  
3659 C  CZ  A ARG A 231 ? 0.55056 0.37087 0.24675 0.03224  -0.02788 -0.10217 254 ARG A CZ  
3660 C  CZ  B ARG A 231 ? 0.55719 0.36256 0.24847 -0.04888 -0.03474 -0.01886 254 ARG A CZ  
3661 N  NH1 A ARG A 231 ? 0.55703 0.37486 0.24407 0.03664  -0.02613 -0.11384 254 ARG A NH1 
3662 N  NH1 B ARG A 231 ? 0.56779 0.36664 0.25176 -0.04891 -0.03566 -0.01719 254 ARG A NH1 
3663 N  NH2 A ARG A 231 ? 0.57377 0.38690 0.24884 0.03268  -0.02156 -0.10242 254 ARG A NH2 
3664 N  NH2 B ARG A 231 ? 0.57914 0.39036 0.24891 -0.04327 -0.02561 -0.02272 254 ARG A NH2 
3691 N  N   . ALA A 232 ? 0.24712 0.11894 0.18024 -0.02856 -0.04877 0.02245  255 ALA A N   
3692 C  CA  . ALA A 232 ? 0.22236 0.10670 0.16185 -0.02449 -0.03500 0.01543  255 ALA A CA  
3693 C  C   . ALA A 232 ? 0.19034 0.11198 0.13941 -0.02754 -0.01386 0.00489  255 ALA A C   
3694 O  O   . ALA A 232 ? 0.20308 0.11870 0.12890 -0.01786 -0.00301 0.00283  255 ALA A O   
3695 C  CB  . ALA A 232 ? 0.26154 0.10936 0.17695 -0.03157 -0.04552 0.02902  255 ALA A CB  
3701 N  N   . PRO A 233 ? 0.17200 0.12663 0.13087 -0.02563 -0.01648 0.01374  256 PRO A N   
3702 C  CA  . PRO A 233 ? 0.18180 0.10148 0.14038 -0.00816 -0.00322 0.00639  256 PRO A CA  
3703 C  C   . PRO A 233 ? 0.16756 0.09881 0.12850 0.00231  -0.00630 0.00552  256 PRO A C   
3704 O  O   . PRO A 233 ? 0.16765 0.10821 0.13474 -0.00415 -0.00395 0.01563  256 PRO A O   
3705 C  CB  . PRO A 233 ? 0.22695 0.16928 0.16658 -0.03492 0.02493  -0.01575 256 PRO A CB  
3706 C  CG  . PRO A 233 ? 0.28755 0.21140 0.16399 0.01043  0.02252  -0.01306 256 PRO A CG  
3707 C  CD  . PRO A 233 ? 0.19996 0.16821 0.13874 -0.02919 -0.00462 0.00051  256 PRO A CD  
3715 N  N   . LEU A 234 ? 0.17826 0.10421 0.11469 -0.01410 -0.01776 0.01275  257 LEU A N   
3716 C  CA  . LEU A 234 ? 0.17330 0.10398 0.12032 -0.01988 -0.01817 0.01652  257 LEU A CA  
3717 C  C   . LEU A 234 ? 0.14877 0.11825 0.11567 -0.01053 -0.00247 0.01758  257 LEU A C   
3718 O  O   . LEU A 234 ? 0.15383 0.11443 0.12985 -0.00960 -0.00214 0.00899  257 LEU A O   
3719 C  CB  . LEU A 234 ? 0.19375 0.12183 0.12538 -0.00426 -0.00658 0.00916  257 LEU A CB  
3720 C  CG  . LEU A 234 ? 0.20940 0.12840 0.13372 -0.00431 -0.00241 -0.01150 257 LEU A CG  
3721 C  CD1 . LEU A 234 ? 0.22298 0.17175 0.13660 -0.01259 -0.02120 0.00342  257 LEU A CD1 
3722 C  CD2 . LEU A 234 ? 0.23296 0.13474 0.14255 -0.02046 -0.02217 -0.00919 257 LEU A CD2 
3734 N  N   . ILE A 235 ? 0.14838 0.09630 0.11871 0.00588  -0.00438 0.00758  258 ILE A N   
3735 C  CA  . ILE A 235 ? 0.15262 0.10991 0.10871 0.00001  -0.01467 0.00618  258 ILE A CA  
3736 C  C   . ILE A 235 ? 0.14017 0.10785 0.11020 -0.00941 -0.00680 -0.00102 258 ILE A C   
3737 O  O   . ILE A 235 ? 0.14959 0.11080 0.12259 0.01532  0.00636  0.01001  258 ILE A O   
3738 C  CB  . ILE A 235 ? 0.16353 0.12440 0.10390 -0.00289 -0.01543 0.01533  258 ILE A CB  
3739 C  CG1 . ILE A 235 ? 0.18616 0.14131 0.10316 0.00248  -0.00782 0.01750  258 ILE A CG1 
3740 C  CG2 . ILE A 235 ? 0.19393 0.13350 0.10745 -0.01051 -0.00989 -0.01448 258 ILE A CG2 
3741 C  CD1 . ILE A 235 ? 0.19183 0.17545 0.10500 0.00396  0.00803  0.00910  258 ILE A CD1 
3753 N  N   . LEU A 236 ? 0.13747 0.10005 0.10506 -0.00088 0.00714  0.00658  259 LEU A N   
3754 C  CA  . LEU A 236 ? 0.14082 0.09504 0.11226 0.00556  0.00108  0.00501  259 LEU A CA  
3755 C  C   . LEU A 236 ? 0.13649 0.11429 0.10247 0.01303  0.00909  0.00137  259 LEU A C   
3756 O  O   . LEU A 236 ? 0.14083 0.11251 0.11657 0.00924  0.01241  0.01263  259 LEU A O   
3757 C  CB  . LEU A 236 ? 0.16044 0.10810 0.10780 -0.00035 -0.00630 0.00733  259 LEU A CB  
3758 C  CG  . LEU A 236 ? 0.16455 0.11840 0.10574 0.00090  -0.00461 0.00549  259 LEU A CG  
3759 C  CD1 . LEU A 236 ? 0.18351 0.11879 0.10525 -0.00646 0.00295  -0.00471 259 LEU A CD1 
3760 C  CD2 . LEU A 236 ? 0.19033 0.14463 0.11307 0.00590  -0.01582 0.01201  259 LEU A CD2 
3772 N  N   . VAL A 237 ? 0.13336 0.10785 0.10762 0.00180  0.01136  -0.00269 260 VAL A N   
3773 C  CA  . VAL A 237 ? 0.12832 0.10335 0.11647 -0.00470 0.00192  0.00003  260 VAL A CA  
3774 C  C   . VAL A 237 ? 0.14288 0.10663 0.10989 0.00288  0.00372  0.00836  260 VAL A C   
3775 O  O   . VAL A 237 ? 0.15121 0.10899 0.11032 0.00615  0.00769  0.00868  260 VAL A O   
3776 C  CB  . VAL A 237 ? 0.17991 0.11169 0.11460 -0.01943 0.00265  0.00303  260 VAL A CB  
3777 C  CG1 . VAL A 237 ? 0.17400 0.15046 0.13777 -0.03506 -0.01415 -0.01324 260 VAL A CG1 
3778 C  CG2 . VAL A 237 ? 0.22063 0.12380 0.11498 0.00534  0.00074  -0.00299 260 VAL A CG2 
3788 N  N   . THR A 238 ? 0.15099 0.10877 0.10205 -0.00004 0.00162  0.00569  261 THR A N   
3789 C  CA  . THR A 238 ? 0.15550 0.10747 0.10228 -0.00541 0.02024  0.01197  261 THR A CA  
3790 C  C   . THR A 238 ? 0.15125 0.12706 0.09775 -0.00207 0.00285  0.00831  261 THR A C   
3791 O  O   . THR A 238 ? 0.14671 0.11887 0.11629 0.00829  0.00995  0.00444  261 THR A O   
3792 C  CB  . THR A 238 ? 0.16463 0.12027 0.10528 -0.00242 0.01008  0.01118  261 THR A CB  
3793 O  OG1 . THR A 238 ? 0.16734 0.12754 0.10643 -0.00149 0.00405  0.00812  261 THR A OG1 
3794 C  CG2 . THR A 238 ? 0.18407 0.14125 0.11365 -0.00669 0.00409  0.01199  261 THR A CG2 
3802 N  N   A TYR A 239 ? 0.15680 0.10403 0.10048 0.00286  0.00263  -0.00196 262 TYR A N   
3803 N  N   B TYR A 239 ? 0.15464 0.11393 0.09541 0.00358  0.00908  0.01368  262 TYR A N   
3804 C  CA  A TYR A 239 ? 0.16514 0.12051 0.09779 0.00024  0.00901  0.00145  262 TYR A CA  
3805 C  CA  B TYR A 239 ? 0.16633 0.11413 0.09381 0.00842  0.00940  0.01305  262 TYR A CA  
3806 C  C   A TYR A 239 ? 0.16893 0.11757 0.09952 -0.00236 0.00680  -0.00716 262 TYR A C   
3807 C  C   B TYR A 239 ? 0.16484 0.11788 0.09434 0.00034  0.00376  0.00147  262 TYR A C   
3808 O  O   A TYR A 239 ? 0.14495 0.12210 0.09729 0.00150  0.00838  -0.00425 262 TYR A O   
3809 O  O   B TYR A 239 ? 0.16307 0.12308 0.09659 -0.00186 -0.00807 0.00302  262 TYR A O   
3810 C  CB  A TYR A 239 ? 0.15769 0.13286 0.10309 -0.01075 0.00256  0.00724  262 TYR A CB  
3811 C  CB  B TYR A 239 ? 0.17272 0.11401 0.09467 0.02200  0.01281  0.02038  262 TYR A CB  
3812 C  CG  A TYR A 239 ? 0.13210 0.10063 0.10921 -0.02465 0.00094  0.01207  262 TYR A CG  
3813 C  CG  B TYR A 239 ? 0.20353 0.16169 0.10047 0.04280  0.01410  0.01947  262 TYR A CG  
3814 C  CD1 A TYR A 239 ? 0.14360 0.11454 0.10234 -0.02088 -0.00131 0.00507  262 TYR A CD1 
3815 C  CD1 B TYR A 239 ? 0.19436 0.17678 0.09999 0.04322  0.01353  0.00910  262 TYR A CD1 
3816 C  CD2 A TYR A 239 ? 0.15205 0.11328 0.11294 -0.01469 -0.00660 -0.00268 262 TYR A CD2 
3817 C  CD2 B TYR A 239 ? 0.23731 0.19697 0.10242 0.04498  0.02108  0.01688  262 TYR A CD2 
3818 C  CE1 A TYR A 239 ? 0.14344 0.13581 0.10900 0.00517  -0.00071 0.00266  262 TYR A CE1 
3819 C  CE1 B TYR A 239 ? 0.20767 0.19883 0.10442 0.04622  0.01690  0.00536  262 TYR A CE1 
3820 C  CE2 A TYR A 239 ? 0.17386 0.13563 0.10818 -0.00753 0.00538  -0.00622 262 TYR A CE2 
3821 C  CE2 B TYR A 239 ? 0.24073 0.21857 0.10727 0.04908  0.02214  0.01541  262 TYR A CE2 
3822 C  CZ  A TYR A 239 ? 0.14476 0.11460 0.10608 0.01116  0.01161  0.00774  262 TYR A CZ  
3823 C  CZ  B TYR A 239 ? 0.21554 0.21812 0.10692 0.05298  0.02248  0.01347  262 TYR A CZ  
3824 O  OH  A TYR A 239 ? 0.17299 0.12858 0.10597 0.02625  0.01540  0.00597  262 TYR A OH  
3825 O  OH  B TYR A 239 ? 0.21834 0.23298 0.10852 0.07169  0.02046  0.01934  262 TYR A OH  
3844 N  N   . PHE A 240 ? 0.16984 0.12214 0.09228 -0.00222 0.01695  -0.00880 263 PHE A N   
3845 C  CA  . PHE A 240 ? 0.16789 0.12687 0.09792 -0.02287 0.01560  -0.00083 263 PHE A CA  
3846 C  C   . PHE A 240 ? 0.17991 0.12672 0.09965 -0.01300 0.01955  -0.00581 263 PHE A C   
3847 O  O   . PHE A 240 ? 0.16069 0.13397 0.10343 -0.01289 0.02651  0.00156  263 PHE A O   
3848 C  CB  . PHE A 240 ? 0.16526 0.12431 0.10527 -0.01843 0.02236  0.00054  263 PHE A CB  
3849 C  CG  . PHE A 240 ? 0.18268 0.12517 0.10543 -0.02116 0.01879  0.00333  263 PHE A CG  
3850 C  CD1 . PHE A 240 ? 0.18109 0.15046 0.09719 0.00030  0.01742  -0.00523 263 PHE A CD1 
3851 C  CD2 . PHE A 240 ? 0.18906 0.14089 0.11017 -0.00922 0.01586  0.01738  263 PHE A CD2 
3852 C  CE1 . PHE A 240 ? 0.18805 0.18016 0.09901 -0.00198 0.01987  -0.00387 263 PHE A CE1 
3853 C  CE2 . PHE A 240 ? 0.19067 0.15020 0.10902 -0.00589 0.01192  0.00784  263 PHE A CE2 
3854 C  CZ  . PHE A 240 ? 0.20715 0.17660 0.09693 -0.00694 0.02713  -0.00027 263 PHE A CZ  
3865 N  N   . THR A 241 ? 0.16689 0.12521 0.09864 -0.01417 0.02654  0.00558  264 THR A N   
3866 C  CA  . THR A 241 ? 0.16737 0.14615 0.10326 -0.02386 0.01485  0.00824  264 THR A CA  
3867 C  C   . THR A 241 ? 0.17220 0.14464 0.10942 -0.01186 0.02581  0.00119  264 THR A C   
3868 O  O   . THR A 241 ? 0.20070 0.14986 0.12018 -0.00621 0.03991  0.01310  264 THR A O   
3869 C  CB  . THR A 241 ? 0.19457 0.13132 0.10985 -0.02006 0.01874  0.00726  264 THR A CB  
3870 O  OG1 . THR A 241 ? 0.19583 0.13730 0.11918 -0.01077 0.00174  0.00911  264 THR A OG1 
3871 C  CG2 . THR A 241 ? 0.19164 0.14808 0.12509 -0.01342 0.00449  -0.00061 264 THR A CG2 
3879 N  N   . GLN A 242 ? 0.17809 0.14294 0.10389 -0.01433 0.02346  0.01154  265 GLN A N   
3880 C  CA  . GLN A 242 ? 0.18854 0.15767 0.11294 0.00514  0.02577  0.01598  265 GLN A CA  
3881 C  C   . GLN A 242 ? 0.19309 0.15626 0.12792 -0.00578 0.02837  0.03638  265 GLN A C   
3882 O  O   . GLN A 242 ? 0.20444 0.15806 0.13019 -0.02770 0.01768  0.02355  265 GLN A O   
3883 C  CB  . GLN A 242 ? 0.18629 0.16815 0.10829 0.00136  0.02147  0.01414  265 GLN A CB  
3884 C  CG  . GLN A 242 ? 0.20087 0.18609 0.11054 0.00191  0.01226  0.00103  265 GLN A CG  
3885 C  CD  . GLN A 242 ? 0.19380 0.17780 0.10766 -0.00783 0.00989  0.01280  265 GLN A CD  
3886 O  OE1 . GLN A 242 ? 0.22599 0.20088 0.10668 -0.00121 0.02199  0.00490  265 GLN A OE1 
3887 N  NE2 . GLN A 242 ? 0.19939 0.16451 0.10457 0.00193  0.00271  0.00381  265 GLN A NE2 
3896 N  N   . PRO A 243 ? 0.18905 0.17280 0.15009 -0.01542 0.04144  0.03911  266 PRO A N   
3897 C  CA  . PRO A 243 ? 0.22262 0.18968 0.17079 -0.00816 0.04380  0.03986  266 PRO A CA  
3898 C  C   . PRO A 243 ? 0.20108 0.16942 0.15868 -0.01922 0.03722  0.03299  266 PRO A C   
3899 O  O   . PRO A 243 ? 0.22349 0.20074 0.17546 -0.02580 0.02720  0.04931  266 PRO A O   
3900 C  CB  . PRO A 243 ? 0.23997 0.21419 0.19648 0.01072  0.06891  0.03102  266 PRO A CB  
3901 C  CG  . PRO A 243 ? 0.25170 0.25348 0.19436 0.02163  0.06780  0.00911  266 PRO A CG  
3902 C  CD  . PRO A 243 ? 0.23075 0.18278 0.16915 0.00107  0.06488  0.03621  266 PRO A CD  
3910 N  N   . GLN A 244 ? 0.20787 0.16183 0.14328 -0.02578 0.02813  0.02911  267 GLN A N   
3911 C  CA  . GLN A 244 ? 0.21291 0.17818 0.13604 -0.02598 0.03643  0.02864  267 GLN A CA  
3912 C  C   . GLN A 244 ? 0.20651 0.17185 0.12644 -0.04091 0.03357  0.02095  267 GLN A C   
3913 O  O   . GLN A 244 ? 0.19813 0.16443 0.11733 -0.02843 0.02852  0.00696  267 GLN A O   
3914 C  CB  . GLN A 244 ? 0.23951 0.16728 0.13368 -0.00804 0.03704  0.02571  267 GLN A CB  
3915 C  CG  . GLN A 244 ? 0.24758 0.18214 0.13492 -0.00611 0.04522  0.02172  267 GLN A CG  
3916 C  CD  . GLN A 244 ? 0.23007 0.18825 0.13338 0.00830  0.03903  0.01245  267 GLN A CD  
3917 O  OE1 . GLN A 244 ? 0.22779 0.19472 0.13695 0.00676  0.04672  -0.00304 267 GLN A OE1 
3918 N  NE2 . GLN A 244 ? 0.24226 0.21941 0.13549 0.03231  0.05604  0.00516  267 GLN A NE2 
3927 N  N   . PRO A 245 ? 0.24086 0.15428 0.14825 -0.04354 0.03081  0.00734  268 PRO A N   
3928 C  CA  . PRO A 245 ? 0.27275 0.16425 0.15288 -0.03516 0.04454  -0.00387 268 PRO A CA  
3929 C  C   . PRO A 245 ? 0.25909 0.16335 0.15191 -0.01277 0.06087  -0.00579 268 PRO A C   
3930 O  O   . PRO A 245 ? 0.24297 0.17301 0.15831 -0.00624 0.06201  0.00390  268 PRO A O   
3931 C  CB  . PRO A 245 ? 0.30102 0.18965 0.17692 -0.05647 0.03839  -0.01701 268 PRO A CB  
3932 C  CG  . PRO A 245 ? 0.32282 0.21850 0.18711 -0.08808 0.03440  -0.01133 268 PRO A CG  
3933 C  CD  . PRO A 245 ? 0.27678 0.17142 0.17094 -0.08098 0.02860  0.00707  268 PRO A CD  
3941 N  N   . LYS A 246 ? 0.23252 0.15648 0.15394 -0.00838 0.05510  0.00742  269 LYS A N   
3942 C  CA  . LYS A 246 ? 0.23668 0.15524 0.16851 -0.01845 0.05125  0.01081  269 LYS A CA  
3943 C  C   . LYS A 246 ? 0.22291 0.14285 0.15640 -0.01395 0.03456  0.01980  269 LYS A C   
3944 O  O   . LYS A 246 ? 0.25039 0.16212 0.16645 0.00099  0.01969  0.02572  269 LYS A O   
3945 C  CB  . LYS A 246 ? 0.27157 0.14217 0.20988 0.00883  0.03865  0.00174  269 LYS A CB  
3946 C  CG  . LYS A 246 ? 0.34786 0.16560 0.24886 -0.00430 0.04692  -0.00912 269 LYS A CG  
3947 C  CD  . LYS A 246 ? 0.43701 0.20192 0.28310 0.01180  0.03121  -0.01670 269 LYS A CD  
3948 C  CE  . LYS A 246 ? 0.50369 0.29910 0.30276 0.01547  0.02413  -0.01719 269 LYS A CE  
3949 N  NZ  . LYS A 246 ? 0.53630 0.34496 0.31584 0.00588  0.01881  -0.00910 269 LYS A NZ  
3963 N  N   . ALA A 247 ? 0.20031 0.14094 0.14051 -0.01727 0.03606  0.01178  270 ALA A N   
3964 C  CA  . ALA A 247 ? 0.22786 0.14165 0.12726 -0.01693 0.02744  0.01643  270 ALA A CA  
3965 C  C   . ALA A 247 ? 0.22635 0.15537 0.13420 -0.00660 0.02481  0.02511  270 ALA A C   
3966 O  O   . ALA A 247 ? 0.23112 0.17341 0.13539 -0.00190 0.03480  0.02139  270 ALA A O   
3967 C  CB  . ALA A 247 ? 0.23651 0.14625 0.11493 -0.02936 0.02684  0.01055  270 ALA A CB  
3973 N  N   . GLU A 248 ? 0.24812 0.17396 0.14313 -0.01885 0.00354  0.02532  271 GLU A N   
3974 C  CA  . GLU A 248 ? 0.26593 0.20553 0.16850 -0.03731 -0.01117 0.04625  271 GLU A CA  
3975 C  C   . GLU A 248 ? 0.23272 0.14791 0.15748 -0.01458 -0.00347 0.03030  271 GLU A C   
3976 O  O   . GLU A 248 ? 0.22962 0.15839 0.15408 -0.01242 0.00199  0.02238  271 GLU A O   
3977 C  CB  . GLU A 248 ? 0.34439 0.30234 0.20447 -0.06028 -0.02198 0.09900  271 GLU A CB  
3978 C  CG  . GLU A 248 ? 0.44788 0.44827 0.24811 -0.05955 -0.02629 0.10472  271 GLU A CG  
3979 C  CD  . GLU A 248 ? 0.52176 0.57084 0.28600 -0.04384 -0.02652 0.10591  271 GLU A CD  
3980 O  OE1 . GLU A 248 ? 0.55698 0.62764 0.30891 -0.03647 -0.03863 0.09532  271 GLU A OE1 
3981 O  OE2 . GLU A 248 ? 0.55723 0.61770 0.29585 -0.04001 -0.01964 0.10644  271 GLU A OE2 
3988 N  N   A SER A 249 ? 0.22982 0.15628 0.17146 -0.00533 0.00797  0.02033  272 SER A N   
3989 N  N   B SER A 249 ? 0.23616 0.14903 0.17173 -0.00623 0.00804  0.02121  272 SER A N   
3990 C  CA  A SER A 249 ? 0.23602 0.17061 0.16901 -0.02003 0.01904  0.00591  272 SER A CA  
3991 C  CA  B SER A 249 ? 0.24141 0.15304 0.17104 -0.01643 0.01578  0.00878  272 SER A CA  
3992 C  C   A SER A 249 ? 0.23668 0.15557 0.14694 -0.02584 0.00323  0.01435  272 SER A C   
3993 C  C   B SER A 249 ? 0.24245 0.15689 0.14879 -0.03415 0.00944  0.01365  272 SER A C   
3994 O  O   A SER A 249 ? 0.23374 0.16262 0.15037 -0.01259 -0.02205 0.03440  272 SER A O   
3995 O  O   B SER A 249 ? 0.24580 0.18631 0.15314 -0.03673 0.00304  0.02268  272 SER A O   
3996 C  CB  A SER A 249 ? 0.23968 0.21947 0.18859 -0.03824 0.03355  -0.00722 272 SER A CB  
3997 C  CB  B SER A 249 ? 0.24399 0.18005 0.19507 -0.01841 0.02018  -0.00247 272 SER A CB  
3998 O  OG  A SER A 249 ? 0.24100 0.22937 0.19546 -0.02936 0.03781  -0.01354 272 SER A OG  
3999 O  OG  B SER A 249 ? 0.22239 0.17792 0.21074 -0.01333 0.01920  -0.00397 272 SER A OG  
4010 N  N   . ARG A 250 ? 0.22941 0.14359 0.12382 -0.02620 -0.00164 0.02217  273 ARG A N   
4011 C  CA  . ARG A 250 ? 0.19745 0.15941 0.11835 -0.03209 -0.00283 0.00911  273 ARG A CA  
4012 C  C   . ARG A 250 ? 0.18963 0.14355 0.11438 -0.02494 -0.01030 0.01112  273 ARG A C   
4013 O  O   . ARG A 250 ? 0.20952 0.14677 0.12514 -0.00992 -0.01303 0.01485  273 ARG A O   
4014 C  CB  . ARG A 250 ? 0.19789 0.18275 0.11689 -0.04819 0.00076  0.01399  273 ARG A CB  
4015 C  CG  . ARG A 250 ? 0.20464 0.18600 0.11647 -0.03589 0.00771  -0.00461 273 ARG A CG  
4016 C  CD  . ARG A 250 ? 0.25595 0.20430 0.12406 -0.04395 0.00700  0.00396  273 ARG A CD  
4017 N  NE  . ARG A 250 ? 0.25303 0.20356 0.12506 -0.02115 0.00626  0.00089  273 ARG A NE  
4018 C  CZ  . ARG A 250 ? 0.28673 0.19677 0.12733 -0.02959 0.01060  0.00393  273 ARG A CZ  
4019 N  NH1 . ARG A 250 ? 0.30799 0.23911 0.13969 -0.01782 0.01360  0.01071  273 ARG A NH1 
4020 N  NH2 . ARG A 250 ? 0.33329 0.23170 0.13434 -0.04328 0.01672  0.00486  273 ARG A NH2 
4034 N  N   A ARG A 251 ? 0.19042 0.16244 0.12004 -0.02475 -0.01480 0.02293  274 ARG A N   
4035 N  N   B ARG A 251 ? 0.16692 0.15828 0.11678 -0.02744 -0.01768 0.02597  274 ARG A N   
4036 C  CA  A ARG A 251 ? 0.19776 0.16822 0.12903 -0.01809 -0.02124 0.02297  274 ARG A CA  
4037 C  CA  B ARG A 251 ? 0.15957 0.15499 0.12411 -0.02277 -0.02899 0.02265  274 ARG A CA  
4038 C  C   A ARG A 251 ? 0.20122 0.15641 0.12867 -0.02130 -0.02589 0.03020  274 ARG A C   
4039 C  C   B ARG A 251 ? 0.17874 0.14390 0.12773 -0.02980 -0.03026 0.03188  274 ARG A C   
4040 O  O   A ARG A 251 ? 0.20896 0.15947 0.13012 -0.00785 -0.01258 0.02700  274 ARG A O   
4041 O  O   B ARG A 251 ? 0.18988 0.14314 0.13011 -0.01917 -0.01101 0.02324  274 ARG A O   
4042 C  CB  A ARG A 251 ? 0.21247 0.18619 0.13686 -0.02502 -0.01753 0.01617  274 ARG A CB  
4043 C  CB  B ARG A 251 ? 0.15850 0.15947 0.12438 -0.02652 -0.03247 0.01184  274 ARG A CB  
4044 C  CG  A ARG A 251 ? 0.22496 0.20256 0.15427 -0.02297 -0.00756 0.01561  274 ARG A CG  
4045 C  CG  B ARG A 251 ? 0.16602 0.16297 0.14733 -0.01496 -0.01782 0.00934  274 ARG A CG  
4046 C  CD  A ARG A 251 ? 0.24776 0.22331 0.16869 -0.02382 0.00023  0.01623  274 ARG A CD  
4047 C  CD  B ARG A 251 ? 0.19124 0.17489 0.16646 -0.02627 -0.01203 0.00083  274 ARG A CD  
4048 N  NE  A ARG A 251 ? 0.27853 0.24645 0.18201 -0.01261 0.01177  0.01868  274 ARG A NE  
4049 N  NE  B ARG A 251 ? 0.21191 0.19418 0.18792 -0.02489 -0.00525 0.00079  274 ARG A NE  
4050 C  CZ  A ARG A 251 ? 0.28714 0.25022 0.18939 -0.02536 0.02203  0.01710  274 ARG A CZ  
4051 C  CZ  B ARG A 251 ? 0.23681 0.23274 0.21035 -0.00263 0.01562  -0.00120 274 ARG A CZ  
4052 N  NH1 A ARG A 251 ? 0.29751 0.24069 0.19158 -0.03147 0.02321  0.01808  274 ARG A NH1 
4053 N  NH1 B ARG A 251 ? 0.24447 0.24559 0.21730 0.02642  0.03294  -0.01143 274 ARG A NH1 
4054 N  NH2 A ARG A 251 ? 0.29221 0.25651 0.19546 -0.02518 0.03336  0.01491  274 ARG A NH2 
4055 N  NH2 B ARG A 251 ? 0.25261 0.22932 0.21948 0.03107  0.01337  0.01584  274 ARG A NH2 
4082 N  N   . ASP A 252 ? 0.20952 0.14727 0.12303 -0.03664 -0.03132 0.02307  275 ASP A N   
4083 C  CA  . ASP A 252 ? 0.22432 0.16194 0.12033 -0.03270 -0.02939 0.01556  275 ASP A CA  
4084 C  C   . ASP A 252 ? 0.21781 0.16129 0.11404 -0.02719 -0.01359 0.00972  275 ASP A C   
4085 O  O   . ASP A 252 ? 0.23754 0.16120 0.11558 -0.03594 -0.01188 -0.00118 275 ASP A O   
4086 C  CB  . ASP A 252 ? 0.26557 0.18731 0.11961 -0.03502 -0.02288 0.00928  275 ASP A CB  
4087 C  CG  . ASP A 252 ? 0.31495 0.20951 0.12212 -0.02781 0.00473  0.00308  275 ASP A CG  
4088 O  OD1 . ASP A 252 ? 0.31361 0.19717 0.11966 -0.05269 0.00489  0.01486  275 ASP A OD1 
4089 O  OD2 . ASP A 252 ? 0.33425 0.23530 0.15007 -0.02531 0.01905  -0.01066 275 ASP A OD2 
4094 N  N   . VAL A 253 ? 0.20310 0.13451 0.11616 -0.02158 -0.00025 0.00295  276 VAL A N   
4095 C  CA  . VAL A 253 ? 0.21278 0.14140 0.12092 -0.01603 0.01728  0.00626  276 VAL A CA  
4096 C  C   . VAL A 253 ? 0.19512 0.14192 0.11764 -0.00648 0.00789  -0.00833 276 VAL A C   
4097 O  O   . VAL A 253 ? 0.19289 0.14708 0.11532 -0.01671 0.00244  -0.00656 276 VAL A O   
4098 C  CB  . VAL A 253 ? 0.19333 0.16904 0.12476 -0.03907 0.01847  0.00232  276 VAL A CB  
4099 C  CG1 . VAL A 253 ? 0.20823 0.16729 0.14207 -0.02922 0.01076  0.01077  276 VAL A CG1 
4100 C  CG2 . VAL A 253 ? 0.20813 0.18490 0.13045 -0.02513 0.01740  -0.00020 276 VAL A CG2 
4110 N  N   . LEU A 254 ? 0.17429 0.13608 0.11682 0.00290  0.00857  -0.01059 277 LEU A N   
4111 C  CA  . LEU A 254 ? 0.15562 0.13351 0.10265 -0.00927 -0.00746 0.00659  277 LEU A CA  
4112 C  C   . LEU A 254 ? 0.19251 0.13246 0.10469 -0.00615 -0.00781 0.00626  277 LEU A C   
4113 O  O   . LEU A 254 ? 0.18449 0.13637 0.10096 -0.00342 -0.01209 -0.00291 277 LEU A O   
4114 C  CB  . LEU A 254 ? 0.17444 0.12930 0.10948 -0.01560 -0.00253 0.00196  277 LEU A CB  
4115 C  CG  . LEU A 254 ? 0.17183 0.12106 0.10668 -0.01213 0.00603  0.01004  277 LEU A CG  
4116 C  CD1 . LEU A 254 ? 0.18229 0.13853 0.11253 -0.01016 0.00722  -0.00092 277 LEU A CD1 
4117 C  CD2 . LEU A 254 ? 0.17771 0.12842 0.11518 -0.01537 -0.00316 0.00621  277 LEU A CD2 
4129 N  N   . ALA A 255 ? 0.18049 0.13552 0.10951 -0.01498 -0.00819 -0.00192 278 ALA A N   
4130 C  CA  . ALA A 255 ? 0.17840 0.13902 0.11723 -0.02496 0.00244  0.00109  278 ALA A CA  
4131 C  C   . ALA A 255 ? 0.18247 0.14108 0.11309 -0.01970 -0.00926 -0.00838 278 ALA A C   
4132 O  O   . ALA A 255 ? 0.20000 0.14130 0.12033 -0.02022 -0.00877 -0.00651 278 ALA A O   
4133 C  CB  . ALA A 255 ? 0.17889 0.15882 0.10949 -0.00939 -0.01243 -0.00070 278 ALA A CB  
4139 N  N   . SER A 256 ? 0.20295 0.13961 0.11137 -0.02003 0.00784  -0.01136 279 SER A N   
4140 C  CA  . SER A 256 ? 0.22193 0.15646 0.11640 -0.01555 0.00628  -0.01096 279 SER A CA  
4141 C  C   . SER A 256 ? 0.21040 0.14719 0.11502 -0.03178 0.01509  -0.01100 279 SER A C   
4142 O  O   . SER A 256 ? 0.23070 0.15779 0.12311 -0.00792 0.00069  -0.02156 279 SER A O   
4143 C  CB  . SER A 256 ? 0.23809 0.16596 0.11725 -0.00750 0.00993  -0.00350 279 SER A CB  
4144 O  OG  . SER A 256 ? 0.29983 0.22783 0.12780 0.01081  0.00017  0.00260  279 SER A OG  
4150 N  N   . ALA A 257 ? 0.20694 0.14785 0.11411 -0.00528 0.00543  -0.01092 280 ALA A N   
4151 C  CA  . ALA A 257 ? 0.19786 0.15416 0.11755 0.00515  -0.00116 0.00015  280 ALA A CA  
4152 C  C   . ALA A 257 ? 0.17584 0.13604 0.11619 0.00593  -0.01417 -0.00327 280 ALA A C   
4153 O  O   . ALA A 257 ? 0.18385 0.14200 0.11953 0.00544  -0.01287 -0.01698 280 ALA A O   
4154 C  CB  . ALA A 257 ? 0.19474 0.16136 0.12494 -0.02918 -0.00366 0.00361  280 ALA A CB  
4160 N  N   . ALA A 258 ? 0.18701 0.12837 0.11095 -0.01085 -0.00372 0.00036  281 ALA A N   
4161 C  CA  . ALA A 258 ? 0.19748 0.13310 0.11111 0.00093  0.00544  -0.00620 281 ALA A CA  
4162 C  C   . ALA A 258 ? 0.21024 0.13361 0.11988 -0.00538 0.00032  -0.01165 281 ALA A C   
4163 O  O   . ALA A 258 ? 0.22052 0.13717 0.12274 -0.00092 0.00462  -0.00188 281 ALA A O   
4164 C  CB  . ALA A 258 ? 0.17336 0.14420 0.11886 -0.00066 0.00431  -0.00019 281 ALA A CB  
4170 N  N   . LYS A 259 ? 0.20913 0.13302 0.11583 -0.00922 -0.00733 -0.02020 282 LYS A N   
4171 C  CA  . LYS A 259 ? 0.22877 0.14993 0.12581 -0.01224 -0.00722 -0.02196 282 LYS A CA  
4172 C  C   . LYS A 259 ? 0.24383 0.13613 0.12994 -0.01009 -0.00930 -0.02509 282 LYS A C   
4173 O  O   . LYS A 259 ? 0.23047 0.15206 0.15123 -0.00965 -0.01599 -0.01647 282 LYS A O   
4174 C  CB  . LYS A 259 ? 0.25257 0.17424 0.13706 0.01752  -0.03041 -0.02934 282 LYS A CB  
4175 C  CG  . LYS A 259 ? 0.34298 0.22471 0.15566 0.03412  -0.03518 -0.05390 282 LYS A CG  
4176 C  CD  . LYS A 259 ? 0.42741 0.30887 0.18444 0.02862  -0.04413 -0.06064 282 LYS A CD  
4177 C  CE  . LYS A 259 ? 0.49660 0.39909 0.21548 0.02328  -0.04614 -0.06115 282 LYS A CE  
4178 N  NZ  . LYS A 259 ? 0.55679 0.46387 0.24114 0.02542  -0.04270 -0.05316 282 LYS A NZ  
4192 N  N   . ILE A 260 ? 0.23312 0.13903 0.12469 -0.00579 0.00517  -0.02356 283 ILE A N   
4193 C  CA  . ILE A 260 ? 0.22876 0.13646 0.12613 -0.00688 0.01144  -0.02064 283 ILE A CA  
4194 C  C   . ILE A 260 ? 0.21781 0.13925 0.13461 -0.01145 0.00180  -0.02517 283 ILE A C   
4195 O  O   . ILE A 260 ? 0.26484 0.14157 0.13788 0.00870  -0.00023 -0.02536 283 ILE A O   
4196 C  CB  . ILE A 260 ? 0.22984 0.16341 0.12879 0.01564  0.01406  -0.02612 283 ILE A CB  
4197 C  CG1 . ILE A 260 ? 0.25344 0.16366 0.13786 0.00481  0.02946  -0.01848 283 ILE A CG1 
4198 C  CG2 . ILE A 260 ? 0.21795 0.18041 0.13965 0.01394  0.01631  -0.02641 283 ILE A CG2 
4199 C  CD1 . ILE A 260 ? 0.26936 0.16764 0.15412 -0.00435 0.02009  -0.00652 283 ILE A CD1 
4211 N  N   . VAL A 261 ? 0.21349 0.14239 0.13813 0.01664  0.00504  -0.02060 284 VAL A N   
4212 C  CA  . VAL A 261 ? 0.21617 0.14748 0.14497 0.01365  -0.00020 -0.01458 284 VAL A CA  
4213 C  C   . VAL A 261 ? 0.24835 0.15684 0.15291 0.01324  -0.01130 -0.00303 284 VAL A C   
4214 O  O   . VAL A 261 ? 0.29297 0.16594 0.16169 0.00567  -0.03650 0.01403  284 VAL A O   
4215 C  CB  . VAL A 261 ? 0.21470 0.14551 0.13935 0.01727  0.01057  -0.01515 284 VAL A CB  
4216 C  CG1 . VAL A 261 ? 0.23860 0.16355 0.14204 0.01684  0.00169  -0.01954 284 VAL A CG1 
4217 C  CG2 . VAL A 261 ? 0.23728 0.14545 0.13985 0.02261  0.00478  -0.00343 284 VAL A CG2 
4227 N  N   . THR A 262 ? 0.23980 0.14059 0.16603 -0.00393 -0.00470 -0.00304 285 THR A N   
4228 C  CA  . THR A 262 ? 0.29114 0.14898 0.18773 -0.00837 -0.00084 0.01016  285 THR A CA  
4229 C  C   . THR A 262 ? 0.40544 0.16021 0.23287 -0.05697 0.00400  -0.01633 285 THR A C   
4230 O  O   . THR A 262 ? 0.39459 0.19512 0.24515 -0.07816 -0.01389 -0.00465 285 THR A O   
4231 C  CB  . THR A 262 ? 0.24949 0.17993 0.17425 -0.00154 -0.00597 0.02324  285 THR A CB  
4232 O  OG1 . THR A 262 ? 0.23872 0.17737 0.17385 -0.02850 -0.02717 0.03349  285 THR A OG1 
4233 C  CG2 . THR A 262 ? 0.24811 0.19409 0.16371 0.01186  0.00109  0.03093  285 THR A CG2 
4241 N  N   A ASP A 263 ? 0.49703 0.19734 0.25278 -0.07187 0.02049  -0.04929 286 ASP A N   
4242 N  N   B ASP A 263 ? 0.49032 0.20190 0.25718 -0.07047 0.01531  -0.03680 286 ASP A N   
4243 C  CA  A ASP A 263 ? 0.60929 0.27591 0.28922 -0.07583 0.01942  -0.06028 286 ASP A CA  
4244 C  CA  B ASP A 263 ? 0.58190 0.25882 0.28784 -0.07721 0.01962  -0.05111 286 ASP A CA  
4245 C  C   A ASP A 263 ? 0.67259 0.29924 0.31331 -0.08049 0.01791  -0.06193 286 ASP A C   
4246 C  C   B ASP A 263 ? 0.65838 0.29880 0.31000 -0.07627 0.02332  -0.05173 286 ASP A C   
4247 O  O   A ASP A 263 ? 0.68785 0.30935 0.32251 -0.07337 0.01258  -0.06222 286 ASP A O   
4248 O  O   B ASP A 263 ? 0.66627 0.29972 0.31420 -0.07067 0.02422  -0.04811 286 ASP A O   
4249 C  CB  A ASP A 263 ? 0.65575 0.33316 0.30275 -0.05102 0.01868  -0.06923 286 ASP A CB  
4250 C  CB  B ASP A 263 ? 0.59449 0.27578 0.29689 -0.07590 0.01940  -0.06413 286 ASP A CB  
4251 C  CG  A ASP A 263 ? 0.70295 0.40348 0.32008 -0.02849 0.01231  -0.06946 286 ASP A CG  
4252 C  CG  B ASP A 263 ? 0.60767 0.29629 0.30748 -0.07629 0.01642  -0.07151 286 ASP A CG  
4253 O  OD1 A ASP A 263 ? 0.72197 0.43381 0.32737 -0.02911 0.00499  -0.06446 286 ASP A OD1 
4254 O  OD1 B ASP A 263 ? 0.61091 0.29839 0.31051 -0.07756 0.01224  -0.08085 286 ASP A OD1 
4255 O  OD2 A ASP A 263 ? 0.72170 0.44208 0.32984 -0.01069 0.01518  -0.06519 286 ASP A OD2 
4256 O  OD2 B ASP A 263 ? 0.61507 0.31145 0.31259 -0.07235 0.01640  -0.06515 286 ASP A OD2 
4265 N  N   . GLY A 264 ? 0.72666 0.34949 0.32669 -0.07308 0.02830  -0.05218 287 GLY A N   
4266 C  CA  . GLY A 264 ? 0.84211 0.41984 0.34772 -0.04988 0.03789  -0.04246 287 GLY A CA  
4267 C  C   . GLY A 264 ? 0.93936 0.48635 0.36256 -0.03882 0.04262  -0.03465 287 GLY A C   
4268 O  O   . GLY A 264 ? 0.96034 0.48513 0.37084 -0.06157 0.03596  -0.02402 287 GLY A O   
4272 N  N   . LEU A 265 ? 0.99499 0.53261 0.36815 -0.02014 0.05203  -0.04052 288 LEU A N   
4273 C  CA  . LEU A 265 ? 1.04375 0.57910 0.37490 -0.00398 0.05804  -0.03145 288 LEU A CA  
4274 C  C   . LEU A 265 ? 1.06939 0.61925 0.38155 0.00444  0.05758  -0.03589 288 LEU A C   
4275 O  O   . LEU A 265 ? 1.08044 0.63820 0.38562 0.01922  0.05913  -0.03641 288 LEU A O   
4276 C  CB  . LEU A 265 ? 1.05417 0.57001 0.37244 0.00167  0.06373  -0.02207 288 LEU A CB  
4277 C  CG  . LEU A 265 ? 1.05742 0.56242 0.37015 0.00446  0.07047  -0.01502 288 LEU A CG  
4278 C  CD1 . LEU A 265 ? 1.05599 0.55365 0.36644 0.00451  0.07839  -0.01880 288 LEU A CD1 
4279 C  CD2 . LEU A 265 ? 1.06278 0.56161 0.37146 0.00499  0.07099  -0.01258 288 LEU A CD2 
4291 C  C1  A 6M9 B .   ? 0.17870 0.12934 0.13584 -0.00842 -0.00147 0.00876  301 6M9 A C1  
4292 C  C2  A 6M9 B .   ? 0.19959 0.13009 0.14732 -0.00634 0.00631  0.01081  301 6M9 A C2  
4293 C  C3  A 6M9 B .   ? 0.22613 0.13540 0.16082 -0.01509 -0.00131 0.01911  301 6M9 A C3  
4294 C  C4  A 6M9 B .   ? 0.21927 0.14025 0.15832 -0.00572 0.01098  0.00883  301 6M9 A C4  
4295 C  C5  A 6M9 B .   ? 0.20368 0.15107 0.14879 -0.00117 0.00882  0.01437  301 6M9 A C5  
4296 C  C6  A 6M9 B .   ? 0.19869 0.14408 0.13996 0.00952  -0.01047 0.01804  301 6M9 A C6  
4297 C  C7  A 6M9 B .   ? 0.19532 0.15929 0.14073 -0.00308 -0.00856 0.02097  301 6M9 A C7  
4298 O  O1  A 6M9 B .   ? 0.20049 0.13857 0.13739 -0.01104 -0.00166 0.01612  301 6M9 A O1  
4299 O  O2  A 6M9 B .   ? 0.17299 0.12036 0.12049 -0.01237 0.01449  0.00457  301 6M9 A O2  
4300 B  B1  A 6M9 B .   ? 0.17257 0.13828 0.13004 -0.00095 0.00237  0.00286  301 6M9 A B1  
4308 S  S   . DMS C .   ? 0.29878 0.31750 0.22074 0.00813  0.06405  -0.00069 302 DMS A S   
4309 O  O   . DMS C .   ? 0.32125 0.33383 0.23245 -0.00031 0.02729  0.01338  302 DMS A O   
4310 C  C1  . DMS C .   ? 0.29660 0.31038 0.21084 0.04356  0.07060  0.01077  302 DMS A C1  
4311 C  C2  . DMS C .   ? 0.31954 0.32976 0.24112 0.00315  0.04298  0.00560  302 DMS A C2  
4318 C  C1  . GOL D .   ? 0.91775 0.78298 0.54422 0.12112  -0.02250 0.16774  303 GOL A C1  
4319 O  O1  . GOL D .   ? 0.91733 0.78953 0.54252 0.11585  -0.01577 0.16772  303 GOL A O1  
4320 C  C2  . GOL D .   ? 0.91886 0.78425 0.54646 0.13334  -0.03080 0.16838  303 GOL A C2  
4321 O  O2  . GOL D .   ? 0.91956 0.78740 0.54611 0.13739  -0.03138 0.16266  303 GOL A O2  
4322 C  C3  . GOL D .   ? 0.92574 0.78605 0.54744 0.14134  -0.03524 0.17367  303 GOL A C3  
4323 O  O3  . GOL D .   ? 0.92747 0.78441 0.54791 0.15146  -0.03822 0.17987  303 GOL A O3  
4332 S  S   . DMS E .   ? 0.65571 0.28168 0.54281 -0.04081 0.32022  0.00603  304 DMS A S   
4333 O  O   . DMS E .   ? 0.63838 0.29466 0.54103 -0.02677 0.33538  0.00638  304 DMS A O   
4334 C  C1  . DMS E .   ? 0.63624 0.25105 0.52585 -0.04603 0.32616  -0.01201 304 DMS A C1  
4335 C  C2  . DMS E .   ? 0.66079 0.29426 0.54257 -0.02959 0.32376  0.00377  304 DMS A C2  
4342 S  S   . SO4 F .   ? 0.58838 0.42507 0.49321 -0.22685 0.11178  -0.07820 305 SO4 A S   
4343 O  O1  . SO4 F .   ? 0.62299 0.44440 0.49711 -0.20776 0.10382  -0.07011 305 SO4 A O1  
4344 O  O2  . SO4 F .   ? 0.61346 0.44486 0.49131 -0.19234 0.10400  -0.08736 305 SO4 A O2  
4345 O  O3  . SO4 F .   ? 0.59518 0.43149 0.49137 -0.22529 0.10989  -0.08290 305 SO4 A O3  
4346 O  O4  . SO4 F .   ? 0.61116 0.46737 0.49850 -0.19218 0.10459  -0.07974 305 SO4 A O4  
4347 S  S   . SO4 G .   ? 0.41742 1.32506 0.94389 -0.00465 0.15115  0.15367  306 SO4 A S   
4348 O  O1  . SO4 G .   ? 0.45362 1.32949 0.94536 0.00115  0.13974  0.15037  306 SO4 A O1  
4349 O  O2  . SO4 G .   ? 0.40117 1.32471 0.94401 0.00146  0.15894  0.15319  306 SO4 A O2  
4350 O  O3  . SO4 G .   ? 0.40238 1.32696 0.94373 -0.00901 0.15239  0.15784  306 SO4 A O3  
4351 O  O4  . SO4 G .   ? 0.41913 1.32578 0.94393 0.00130  0.14806  0.15140  306 SO4 A O4  
4352 S  S   . SO4 H .   ? 0.52222 0.23912 0.45504 -0.04024 -0.27071 -0.01054 307 SO4 A S   
4353 O  O1  . SO4 H .   ? 0.49762 0.29637 0.46636 -0.05296 -0.27009 -0.00392 307 SO4 A O1  
4354 O  O2  . SO4 H .   ? 0.49904 0.21752 0.45405 0.00670  -0.28425 -0.01254 307 SO4 A O2  
4355 O  O3  . SO4 H .   ? 0.55337 0.23492 0.45978 -0.04471 -0.25752 -0.01923 307 SO4 A O3  
4356 O  O4  . SO4 H .   ? 0.60061 0.26405 0.48236 -0.00550 -0.21404 -0.00663 307 SO4 A O4  
4357 S  S   A SO4 I .   ? 0.27163 0.14989 0.27384 -0.03047 0.04656  0.01450  308 SO4 A S   
4358 O  O1  A SO4 I .   ? 0.27806 0.17297 0.28223 -0.02335 0.03563  0.00729  308 SO4 A O1  
4359 O  O2  A SO4 I .   ? 0.27866 0.13144 0.27589 -0.05390 0.06010  0.02159  308 SO4 A O2  
4360 O  O3  A SO4 I .   ? 0.28576 0.16729 0.27632 -0.02676 0.05931  0.01173  308 SO4 A O3  
4361 O  O4  A SO4 I .   ? 0.28283 0.15650 0.27754 -0.00937 0.05093  0.03526  308 SO4 A O4  
4362 S  S   A SO4 J .   ? 0.79397 0.42368 0.66394 0.09582  0.03114  0.16634  309 SO4 A S   
4363 O  O1  A SO4 J .   ? 0.78897 0.41960 0.66338 0.10577  0.02988  0.17001  309 SO4 A O1  
4364 O  O2  A SO4 J .   ? 0.79474 0.42360 0.66461 0.08936  0.03003  0.16738  309 SO4 A O2  
4365 O  O3  A SO4 J .   ? 0.79026 0.43222 0.66383 0.09560  0.03096  0.16186  309 SO4 A O3  
4366 O  O4  A SO4 J .   ? 0.79408 0.42827 0.66390 0.10105  0.02771  0.16268  309 SO4 A O4  
4367 CL CL  . CL  K .   ? 0.25399 0.17974 0.14612 -0.00548 -0.04751 0.01510  310 CL  A CL  
4368 NA NA  . NA  L .   ? 0.23559 0.20617 0.17144 -0.01626 0.00815  0.00932  311 NA  A NA  
4369 NA NA  . NA  M .   ? 0.23629 0.19679 0.16032 -0.00556 -0.01843 0.00189  312 NA  A NA  
4370 NA NA  A NA  N .   ? 0.46621 0.31106 0.25630 0.00142  -0.09427 -0.00941 313 NA  A NA  
4371 S  S   B SO4 O .   ? 0.22149 0.11637 0.23189 0.02406  0.01262  0.01740  314 SO4 A S   
4372 O  O1  B SO4 O .   ? 0.21462 0.11854 0.23918 0.01697  0.01455  -0.00848 314 SO4 A O1  
4373 O  O2  B SO4 O .   ? 0.20586 0.17325 0.23487 0.01408  0.03925  -0.00660 314 SO4 A O2  
4374 O  O3  B SO4 O .   ? 0.21118 0.19178 0.23487 0.02210  0.00750  0.02815  314 SO4 A O3  
4375 O  O4  B SO4 O .   ? 0.22368 0.18976 0.23429 0.01728  -0.01540 0.01481  314 SO4 A O4  
4376 O  O   . HOH P .   ? 0.66691 0.56865 0.22362 -0.15484 -0.06357 -0.05900 401 HOH A O   
4377 O  O   . HOH P .   ? 0.51811 0.47601 0.82954 -0.16604 -0.34340 0.20337  402 HOH A O   
4378 O  O   . HOH P .   ? 0.27080 0.56379 0.77149 0.00560  0.02298  0.37425  403 HOH A O   
4379 O  O   . HOH P .   ? 0.47588 0.48893 0.38619 0.17233  -0.06849 -0.18149 404 HOH A O   
4380 O  O   . HOH P .   ? 0.49104 0.29440 0.48145 -0.04023 0.15800  -0.15305 405 HOH A O   
4381 O  O   . HOH P .   ? 0.99929 0.26374 0.42698 -0.06385 0.02300  -0.01355 406 HOH A O   
4382 O  O   . HOH P .   ? 0.61177 0.62460 0.27713 0.09081  -0.05402 -0.18885 407 HOH A O   
4383 O  O   . HOH P .   ? 0.48723 0.28588 0.48180 0.05550  0.13239  0.10807  408 HOH A O   
4384 O  O   . HOH P .   ? 0.57742 0.29882 0.63095 -0.06139 0.15988  -0.00653 409 HOH A O   
4385 O  O   A HOH P .   ? 0.16263 0.14166 0.25580 0.01008  0.06814  0.01144  410 HOH A O   
4386 O  O   B HOH P .   ? 0.32597 0.17315 0.48694 0.03611  0.11920  -0.06354 410 HOH A O   
4387 O  O   . HOH P .   ? 0.70473 1.06882 0.74185 0.40909  0.19801  0.23108  411 HOH A O   
4388 O  O   A HOH P .   ? 0.27410 0.20233 0.15650 0.04595  -0.01987 -0.01735 412 HOH A O   
4389 O  O   . HOH P .   ? 1.34518 0.88797 0.60249 0.28667  -0.11595 0.24393  413 HOH A O   
4390 O  O   . HOH P .   ? 0.92513 0.74399 0.55244 0.22800  -0.02912 -0.14864 414 HOH A O   
4391 O  O   . HOH P .   ? 0.48078 0.53137 0.41979 -0.06766 0.11058  0.08549  415 HOH A O   
4392 O  O   . HOH P .   ? 0.59196 0.78383 0.34458 -0.13209 -0.15576 -0.07099 416 HOH A O   
4393 O  O   . HOH P .   ? 0.20384 0.11764 0.14816 -0.01459 0.01372  -0.01624 417 HOH A O   
4394 O  O   . HOH P .   ? 0.72145 0.55881 0.34907 -0.02351 0.07388  -0.03338 418 HOH A O   
4395 O  O   . HOH P .   ? 0.48018 0.55420 0.38148 -0.25781 0.03380  -0.16502 419 HOH A O   
4396 O  O   . HOH P .   ? 0.93141 0.48893 0.72957 0.17785  0.13365  0.28306  420 HOH A O   
4397 O  O   . HOH P .   ? 0.37620 0.23918 0.32845 -0.00663 -0.09615 0.00957  421 HOH A O   
4398 O  O   . HOH P .   ? 0.30533 0.45107 0.51237 -0.17384 0.13386  -0.15870 422 HOH A O   
4399 O  O   . HOH P .   ? 0.40705 0.58450 0.35209 0.08659  -0.13062 -0.14064 423 HOH A O   
4400 O  O   . HOH P .   ? 0.46510 0.33069 0.54169 -0.10318 -0.18932 0.10466  424 HOH A O   
4401 O  O   . HOH P .   ? 0.60808 0.31230 0.36013 0.17216  0.17463  0.12002  425 HOH A O   
4402 O  O   . HOH P .   ? 0.44087 0.37318 0.37557 -0.00793 -0.21077 0.03925  426 HOH A O   
4403 O  O   . HOH P .   ? 0.52430 1.09046 0.31718 -0.04209 0.01873  0.00616  427 HOH A O   
4404 O  O   B HOH P .   ? 0.52768 0.17957 0.14389 0.05399  0.05537  0.00604  428 HOH A O   
4405 O  O   . HOH P .   ? 0.91722 0.33224 0.39646 0.21555  0.16165  0.06872  429 HOH A O   
4406 O  O   . HOH P .   ? 0.77364 0.46871 0.37639 0.33761  -0.07017 -0.04154 430 HOH A O   
4407 O  O   . HOH P .   ? 0.72389 0.58529 0.41635 -0.07859 -0.09309 0.03901  431 HOH A O   
4408 O  O   . HOH P .   ? 1.00320 0.44520 0.69558 -0.32306 -0.12122 0.06207  432 HOH A O   
4409 O  O   . HOH P .   ? 0.61007 0.35415 0.49294 0.06581  0.05655  0.20331  433 HOH A O   
4410 O  O   . HOH P .   ? 0.86862 0.54557 0.64572 0.24560  0.11547  -0.20634 434 HOH A O   
4411 O  O   . HOH P .   ? 0.42111 0.22203 0.36612 0.06708  -0.01646 0.01925  435 HOH A O   
4412 O  O   . HOH P .   ? 0.59904 0.28157 0.22932 -0.08418 -0.09882 0.02853  436 HOH A O   
4413 O  O   . HOH P .   ? 0.46366 0.31570 0.36278 0.08774  0.16234  0.08667  437 HOH A O   
4414 O  O   . HOH P .   ? 0.58186 0.26805 0.43847 -0.17954 -0.04010 0.07231  438 HOH A O   
4415 O  O   . HOH P .   ? 0.36760 0.21341 0.16924 0.05541  0.04755  0.03465  439 HOH A O   
4416 O  O   . HOH P .   ? 0.28079 0.60482 0.18693 -0.00978 0.05362  0.04128  440 HOH A O   
4417 O  O   . HOH P .   ? 0.45730 0.19400 0.58074 -0.05669 -0.05391 0.05792  441 HOH A O   
4418 O  O   . HOH P .   ? 0.37085 0.92798 0.65131 0.13563  0.19818  0.11029  442 HOH A O   
4419 O  O   . HOH P .   ? 0.24771 0.16222 0.12822 0.03970  -0.00475 0.01746  443 HOH A O   
4420 O  O   . HOH P .   ? 0.60796 0.27708 0.78366 -0.06082 0.23946  -0.13131 444 HOH A O   
4421 O  O   . HOH P .   ? 0.34536 0.23566 0.30828 -0.00321 0.06500  -0.05933 445 HOH A O   
4422 O  O   . HOH P .   ? 0.44128 0.16911 0.17078 -0.01373 0.03654  0.02142  446 HOH A O   
4423 O  O   . HOH P .   ? 0.16245 0.17226 0.20343 -0.00230 0.04595  -0.02992 447 HOH A O   
4424 O  O   . HOH P .   ? 0.35164 0.22815 0.76032 0.07785  0.01801  0.01316  448 HOH A O   
4425 O  O   . HOH P .   ? 0.24930 0.36084 0.14992 -0.12145 -0.02974 0.00073  449 HOH A O   
4426 O  O   . HOH P .   ? 0.21851 0.20077 0.16476 0.08533  0.04449  0.03232  450 HOH A O   
4427 O  O   . HOH P .   ? 0.24405 0.17333 0.15314 -0.01546 -0.02544 0.01024  451 HOH A O   
4428 O  O   . HOH P .   ? 0.55417 0.21344 0.19235 0.06206  0.10539  0.00199  452 HOH A O   
4429 O  O   . HOH P .   ? 0.36761 0.16362 0.42450 0.02225  0.18009  0.03906  453 HOH A O   
4430 O  O   . HOH P .   ? 0.60344 0.53771 0.26574 0.14390  0.17144  0.03521  454 HOH A O   
4431 O  O   . HOH P .   ? 0.17877 0.21610 0.16810 -0.00112 0.00423  0.06814  455 HOH A O   
4432 O  O   . HOH P .   ? 0.21184 0.15406 0.12242 -0.02052 0.01138  0.00924  456 HOH A O   
4433 O  O   . HOH P .   ? 0.16008 0.12568 0.13603 -0.00755 0.01536  0.00042  457 HOH A O   
4434 O  O   . HOH P .   ? 0.28079 0.20323 0.22271 0.02317  -0.02850 0.00704  458 HOH A O   
4435 O  O   . HOH P .   ? 0.46133 0.45254 0.29830 0.10102  0.01880  0.08301  459 HOH A O   
4436 O  O   . HOH P .   ? 0.18784 0.20212 0.14202 -0.01288 -0.00298 0.01714  460 HOH A O   
4437 O  O   . HOH P .   ? 0.29715 0.44378 0.51114 -0.08983 -0.05486 0.17652  461 HOH A O   
4438 O  O   . HOH P .   ? 0.28379 0.17363 0.18610 0.00807  -0.05518 -0.04092 462 HOH A O   
4439 O  O   . HOH P .   ? 0.43861 0.55627 0.46586 -0.12777 -0.01689 0.27830  463 HOH A O   
4440 O  O   . HOH P .   ? 0.38379 0.50805 0.17308 -0.05140 -0.03001 0.05910  464 HOH A O   
4441 O  O   . HOH P .   ? 0.23558 0.20008 0.32572 -0.00774 0.05500  0.03887  465 HOH A O   
4442 O  O   . HOH P .   ? 0.34283 0.37486 0.53513 0.01243  0.01483  -0.06984 466 HOH A O   
4443 O  O   . HOH P .   ? 0.23156 0.17700 0.15509 0.04140  -0.02275 0.00975  467 HOH A O   
4444 O  O   . HOH P .   ? 0.27587 0.18997 0.26607 0.01314  -0.05185 0.01131  468 HOH A O   
4445 O  O   . HOH P .   ? 0.72903 0.38957 0.28979 0.21544  0.06004  0.08684  469 HOH A O   
4446 O  O   . HOH P .   ? 0.52605 0.84969 0.69234 -0.19687 -0.20491 0.38665  470 HOH A O   
4447 O  O   . HOH P .   ? 0.21306 0.16137 0.22184 0.00250  0.02248  0.00882  471 HOH A O   
4448 O  O   . HOH P .   ? 0.34985 0.27916 0.18211 0.12275  0.03698  0.06816  472 HOH A O   
4449 O  O   . HOH P .   ? 0.67972 0.92480 0.31702 0.15903  -0.04041 0.10561  473 HOH A O   
4450 O  O   . HOH P .   ? 0.42519 0.46707 0.71353 -0.13995 0.26782  -0.27066 474 HOH A O   
4451 O  O   . HOH P .   ? 0.21908 0.18177 0.16818 0.02138  0.01215  0.01219  475 HOH A O   
4452 O  O   . HOH P .   ? 0.26644 0.20883 0.21227 -0.02555 -0.03924 -0.04338 476 HOH A O   
4453 O  O   . HOH P .   ? 0.16529 0.20299 0.16177 -0.02676 0.02025  -0.00773 477 HOH A O   
4454 O  O   . HOH P .   ? 0.34248 0.58083 0.44504 0.12811  0.04589  0.16058  478 HOH A O   
4455 O  O   . HOH P .   ? 0.20966 0.14865 0.12437 -0.01049 0.02290  -0.00979 479 HOH A O   
4456 O  O   . HOH P .   ? 0.42152 0.18851 0.17289 0.09092  -0.10629 -0.02008 480 HOH A O   
4457 O  O   . HOH P .   ? 0.81584 0.46017 0.55364 -0.17379 0.23356  -0.12358 481 HOH A O   
4458 O  O   . HOH P .   ? 0.31905 0.54649 0.96009 0.04477  0.05977  0.17661  482 HOH A O   
4459 O  O   . HOH P .   ? 0.24304 0.16963 0.18436 0.00520  -0.02076 -0.03136 483 HOH A O   
4460 O  O   . HOH P .   ? 0.19742 0.15308 0.11453 -0.01948 0.02842  -0.00323 484 HOH A O   
4461 O  O   . HOH P .   ? 0.30415 0.54572 0.17084 0.16541  0.01748  0.01375  485 HOH A O   
4462 O  O   . HOH P .   ? 0.21677 0.14372 0.14919 -0.00853 0.00485  0.00828  486 HOH A O   
4463 O  O   . HOH P .   ? 0.26412 0.25375 0.15669 -0.04068 0.02490  -0.00268 487 HOH A O   
4464 O  O   . HOH P .   ? 0.20571 0.17280 0.11493 0.00552  -0.02759 0.00261  488 HOH A O   
4465 O  O   . HOH P .   ? 0.31105 0.42119 0.21357 0.05689  0.04239  0.03100  489 HOH A O   
4466 O  O   . HOH P .   ? 0.21799 0.14289 0.20903 -0.00883 0.01046  -0.00321 490 HOH A O   
4467 O  O   . HOH P .   ? 0.54691 0.42721 0.25320 -0.27942 -0.08623 0.05581  491 HOH A O   
4468 O  O   . HOH P .   ? 0.19830 0.18409 0.16381 -0.00175 -0.00043 -0.00637 492 HOH A O   
4469 O  O   . HOH P .   ? 0.62726 0.34853 0.30689 0.08761  0.07021  0.08414  493 HOH A O   
4470 O  O   . HOH P .   ? 0.46100 0.42709 0.26430 -0.02409 -0.00695 0.15460  494 HOH A O   
4471 O  O   . HOH P .   ? 0.26635 0.18800 0.22067 -0.01708 0.01305  0.00801  495 HOH A O   
4472 O  O   . HOH P .   ? 0.58079 0.32652 0.88426 -0.11704 -0.32286 0.11454  496 HOH A O   
4473 O  O   . HOH P .   ? 0.38200 0.24864 0.41092 -0.10260 -0.15904 0.11841  497 HOH A O   
4474 O  O   . HOH P .   ? 0.58704 0.48694 0.62517 0.09775  -0.26780 0.15308  498 HOH A O   
4475 O  O   . HOH P .   ? 0.24938 0.17031 0.17276 -0.02956 -0.02098 -0.02128 499 HOH A O   
4476 O  O   . HOH P .   ? 0.47678 0.36215 0.44074 -0.04409 0.22056  0.03639  500 HOH A O   
4477 O  O   . HOH P .   ? 0.24930 0.17586 0.21102 -0.01889 -0.01201 -0.00857 501 HOH A O   
4478 O  O   . HOH P .   ? 0.47489 0.63282 0.52255 0.07085  -0.19111 -0.03979 502 HOH A O   
4479 O  O   . HOH P .   ? 0.55572 0.29966 0.23778 0.05551  0.06172  -0.06406 503 HOH A O   
4480 O  O   . HOH P .   ? 0.25959 0.20388 0.15339 0.04857  0.06228  0.03390  504 HOH A O   
4481 O  O   . HOH P .   ? 0.16968 0.12544 0.12803 -0.01704 -0.01555 -0.00725 505 HOH A O   
4482 O  O   . HOH P .   ? 0.32165 0.18588 0.18633 -0.01406 -0.01121 -0.00041 506 HOH A O   
4483 O  O   . HOH P .   ? 0.30704 0.28769 0.50909 -0.03309 -0.00734 0.10907  507 HOH A O   
4484 O  O   . HOH P .   ? 0.56101 0.35877 0.26824 0.15369  -0.10611 0.06026  508 HOH A O   
4485 O  O   . HOH P .   ? 0.76567 0.74879 0.29790 -0.13787 -0.04795 -0.16781 509 HOH A O   
4486 O  O   . HOH P .   ? 0.40950 0.95416 0.46422 -0.14730 0.08310  -0.32348 510 HOH A O   
4487 O  O   . HOH P .   ? 0.31382 0.21291 0.22486 -0.02988 -0.05267 0.05955  511 HOH A O   
4488 O  O   . HOH P .   ? 0.28487 0.28819 0.19415 -0.03396 0.03676  -0.02569 512 HOH A O   
4489 O  O   . HOH P .   ? 0.34867 0.36747 0.34084 0.00059  -0.10269 0.06409  513 HOH A O   
4490 O  O   . HOH P .   ? 0.36316 0.20674 0.47421 -0.03950 -0.11953 0.06165  514 HOH A O   
4491 O  O   . HOH P .   ? 0.28592 0.53188 0.70654 -0.14157 0.08024  0.06787  515 HOH A O   
4492 O  O   . HOH P .   ? 0.22072 0.18192 0.20871 0.00259  0.03743  0.00951  516 HOH A O   
4493 O  O   . HOH P .   ? 0.57366 0.53184 0.73438 0.25052  -0.06026 -0.25082 517 HOH A O   
4494 O  O   . HOH P .   ? 0.25100 0.25709 0.22072 -0.02724 -0.00652 -0.06310 518 HOH A O   
4495 O  O   . HOH P .   ? 0.20980 0.40973 0.35376 -0.00665 -0.06492 -0.08177 519 HOH A O   
4496 O  O   . HOH P .   ? 0.25312 0.22756 0.23522 0.00765  0.01369  -0.04536 520 HOH A O   
4497 O  O   . HOH P .   ? 0.20733 0.31795 0.63806 0.04923  0.09501  -0.04435 521 HOH A O   
4498 O  O   . HOH P .   ? 0.39577 0.41657 0.15247 0.00212  0.00852  0.00798  522 HOH A O   
4499 O  O   . HOH P .   ? 0.26834 0.19548 0.34772 0.03117  0.05707  0.00563  523 HOH A O   
4500 O  O   . HOH P .   ? 0.75417 0.42785 0.22964 0.11410  0.05320  -0.06055 524 HOH A O   
4501 O  O   . HOH P .   ? 0.32567 0.57812 0.26545 0.14736  -0.00203 -0.09425 525 HOH A O   
4502 O  O   . HOH P .   ? 0.16544 0.12933 0.14251 -0.00111 0.00462  -0.01345 526 HOH A O   
4503 O  O   . HOH P .   ? 0.48743 0.29156 0.41294 -0.00652 -0.07856 -0.12208 527 HOH A O   
4504 O  O   A HOH P .   ? 0.18652 0.10970 0.11409 0.00163  0.00510  0.01524  528 HOH A O   
4505 O  O   B HOH P .   ? 0.23856 0.17738 0.33737 0.01198  -0.04836 0.12200  528 HOH A O   
4506 O  O   . HOH P .   ? 0.30760 0.58805 0.17630 -0.11078 0.00753  -0.00005 529 HOH A O   
4507 O  O   . HOH P .   ? 0.17510 0.15344 0.14505 0.00675  -0.00705 -0.00647 530 HOH A O   
4508 O  O   . HOH P .   ? 0.44868 0.38707 0.40817 -0.14656 -0.08646 0.00095  531 HOH A O   
4509 O  O   . HOH P .   ? 0.60755 0.27621 0.33175 0.02186  -0.12520 -0.06969 532 HOH A O   
4510 O  O   . HOH P .   ? 0.71614 0.58967 0.61900 -0.21167 0.22161  -0.04899 533 HOH A O   
4511 O  O   . HOH P .   ? 0.74103 0.53504 0.67840 -0.16623 0.13514  -0.04606 534 HOH A O   
4512 O  O   . HOH P .   ? 0.30996 0.21951 0.65738 0.02825  -0.04191 -0.04024 535 HOH A O   
4513 O  O   . HOH P .   ? 0.30859 0.21236 0.15835 0.01887  0.04930  0.03333  536 HOH A O   
4514 O  O   . HOH P .   ? 0.40056 0.31176 0.23619 -0.04047 -0.04765 -0.01301 537 HOH A O   
4515 O  O   . HOH P .   ? 0.42086 0.94651 0.25430 -0.16970 0.00608  0.04198  538 HOH A O   
4516 O  O   . HOH P .   ? 0.54580 0.22994 0.42850 0.12061  0.19062  0.01899  539 HOH A O   
4517 O  O   . HOH P .   ? 0.34273 0.17700 0.32741 0.01928  -0.11671 0.01492  540 HOH A O   
4518 O  O   . HOH P .   ? 0.31095 0.24787 0.22295 -0.01002 -0.02452 -0.01924 541 HOH A O   
4519 O  O   . HOH P .   ? 0.33946 0.26080 0.30187 -0.08691 -0.00357 0.10002  542 HOH A O   
4520 O  O   . HOH P .   ? 0.26430 0.28969 0.32947 0.01392  0.08493  0.06797  543 HOH A O   
4521 O  O   . HOH P .   ? 0.63334 0.63427 0.89626 0.23338  0.07273  0.11054  544 HOH A O   
4522 O  O   . HOH P .   ? 0.26665 0.32261 0.35555 0.08572  0.00217  -0.10489 545 HOH A O   
4523 O  O   . HOH P .   ? 0.54847 0.38713 0.99737 0.13623  0.01252  -0.14857 546 HOH A O   
4524 O  O   . HOH P .   ? 0.52966 0.38758 0.64167 -0.10046 -0.29128 0.02654  547 HOH A O   
4525 O  O   . HOH P .   ? 0.49004 0.87268 0.31214 -0.01062 0.03387  -0.11383 548 HOH A O   
4526 O  O   . HOH P .   ? 0.25390 0.40463 0.28997 -0.06963 -0.03331 -0.08292 549 HOH A O   
4527 O  O   . HOH P .   ? 0.33990 0.22466 0.40556 0.03868  -0.20419 0.00229  550 HOH A O   
4528 O  O   . HOH P .   ? 0.39369 0.56309 0.80410 0.18608  -0.05481 -0.26057 551 HOH A O   
4529 O  O   . HOH P .   ? 0.34738 0.23929 0.52067 0.00740  -0.01820 0.06583  552 HOH A O   
4530 O  O   . HOH P .   ? 0.24900 0.15410 0.14687 0.00465  -0.00405 -0.01696 553 HOH A O   
4531 O  O   . HOH P .   ? 0.41764 0.45469 0.61100 0.06210  0.22400  -0.00793 554 HOH A O   
4532 O  O   . HOH P .   ? 0.22955 0.27046 0.19931 0.04572  0.05301  -0.02227 555 HOH A O   
4533 O  O   . HOH P .   ? 0.26473 0.22095 0.19899 -0.02744 -0.03978 0.05233  556 HOH A O   
4534 O  O   . HOH P .   ? 0.54621 0.25285 0.21659 0.00263  0.04983  -0.00372 557 HOH A O   
4535 O  O   . HOH P .   ? 0.20365 0.17766 0.19217 0.00256  -0.01673 0.00570  558 HOH A O   
4536 O  O   . HOH P .   ? 0.32360 0.31924 0.53855 -0.03619 0.13008  -0.00072 559 HOH A O   
4537 O  O   . HOH P .   ? 0.29492 0.31953 0.34830 -0.05777 -0.08318 0.07375  560 HOH A O   
4538 O  O   . HOH P .   ? 0.35913 0.30662 0.22028 -0.06239 0.03293  -0.03638 561 HOH A O   
4539 O  O   . HOH P .   ? 0.35788 0.29647 0.27422 -0.05177 -0.04974 0.05578  562 HOH A O   
4540 O  O   . HOH P .   ? 0.29136 0.34194 0.38246 -0.09013 -0.08500 0.10390  563 HOH A O   
4541 O  O   A HOH P .   ? 0.46966 0.35620 0.20712 -0.00816 0.15225  -0.00820 564 HOH A O   
4542 O  O   A HOH P .   ? 0.60877 0.25889 0.39385 -0.02057 -0.02527 0.08867  565 HOH A O   
4543 O  O   . HOH P .   ? 0.36770 0.28392 0.17575 0.05764  -0.01272 -0.02513 566 HOH A O   
4544 O  O   . HOH P .   ? 0.44992 0.28444 0.37693 -0.02700 -0.14754 0.03318  567 HOH A O   
4545 O  O   . HOH P .   ? 0.38554 0.61059 0.37291 0.02742  -0.08744 -0.09335 568 HOH A O   
4546 O  O   . HOH P .   ? 0.42437 0.28391 0.27235 0.05964  0.09449  0.00542  569 HOH A O   
4547 O  O   . HOH P .   ? 0.29331 0.32227 0.17110 -0.12575 0.03640  -0.05534 570 HOH A O   
4548 O  O   . HOH P .   ? 0.35297 0.50136 0.73983 0.13624  0.20431  0.32737  571 HOH A O   
4549 O  O   . HOH P .   ? 0.21792 0.19562 0.16548 -0.01803 0.01576  0.01152  572 HOH A O   
4550 O  O   . HOH P .   ? 0.26759 0.20927 0.20135 0.00599  0.02684  0.03087  573 HOH A O   
4551 O  O   . HOH P .   ? 0.41002 0.46392 0.46153 -0.01010 0.08363  0.25996  574 HOH A O   
4552 O  O   . HOH P .   ? 0.48051 0.53781 0.27227 -0.26282 0.02943  -0.06482 575 HOH A O   
4553 O  O   . HOH P .   ? 0.30446 0.23911 0.17471 -0.01415 -0.01320 -0.01014 576 HOH A O   
4554 O  O   . HOH P .   ? 0.30024 0.33196 0.18912 -0.10706 -0.00955 -0.00041 577 HOH A O   
4555 O  O   . HOH P .   ? 0.22103 0.16551 0.20730 0.01000  0.01634  0.02011  578 HOH A O   
4556 O  O   . HOH P .   ? 0.49263 0.67739 1.12664 0.16923  -0.13070 -0.24867 579 HOH A O   
4557 O  O   . HOH P .   ? 0.25820 0.19774 0.41932 0.02958  0.09048  -0.03698 580 HOH A O   
4558 O  O   . HOH P .   ? 0.54580 0.23349 0.78654 -0.03194 -0.12699 0.07503  581 HOH A O   
4559 O  O   . HOH P .   ? 0.53989 0.48136 0.38948 0.13856  0.05845  -0.03905 582 HOH A O   
4560 O  O   . HOH P .   ? 0.68027 0.34953 0.44037 -0.24170 0.15572  -0.04848 583 HOH A O   
4561 O  O   . HOH P .   ? 0.41233 0.36531 0.80605 -0.11060 0.28709  -0.21442 584 HOH A O   
4562 O  O   . HOH P .   ? 0.21056 0.22458 0.40221 -0.03311 0.04631  -0.03073 585 HOH A O   
4563 O  O   . HOH P .   ? 0.38109 0.77384 0.62770 0.01883  0.02610  -0.04328 586 HOH A O   
4564 O  O   . HOH P .   ? 0.34656 0.61646 0.22916 -0.13119 -0.05000 0.14651  587 HOH A O   
4565 O  O   . HOH P .   ? 0.75928 0.37835 0.52356 0.09618  0.35867  0.08931  588 HOH A O   
4566 O  O   . HOH P .   ? 0.43202 0.25376 0.22778 -0.06669 -0.01008 -0.01243 589 HOH A O   
4567 O  O   . HOH P .   ? 0.36141 0.15114 0.20118 -0.04305 -0.11370 0.02683  590 HOH A O   
4568 O  O   . HOH P .   ? 0.40747 0.74726 0.70871 0.05620  0.02599  -0.01560 591 HOH A O   
4569 O  O   . HOH P .   ? 0.41216 0.58332 0.41079 0.04988  -0.03861 0.24617  592 HOH A O   
4570 O  O   . HOH P .   ? 0.27374 0.26941 0.49677 0.10980  0.12910  0.14589  593 HOH A O   
4571 O  O   . HOH P .   ? 0.33255 0.73307 0.31845 -0.23599 -0.01994 -0.04249 594 HOH A O   
4572 O  O   . HOH P .   ? 0.24362 0.29598 0.19290 0.08718  0.03342  0.02514  595 HOH A O   
4573 O  O   . HOH P .   ? 0.68372 0.45374 1.07439 -0.08942 0.42296  -0.12358 596 HOH A O   
4574 O  O   . HOH P .   ? 0.27656 0.73874 0.28112 -0.13509 0.07213  -0.15100 597 HOH A O   
4575 O  O   . HOH P .   ? 0.55084 0.22262 0.51276 -0.10398 -0.05334 0.01559  598 HOH A O   
4576 O  O   B HOH P .   ? 0.46161 0.32104 0.23513 0.08524  -0.05758 -0.06481 599 HOH A O   
4577 O  O   . HOH P .   ? 0.24865 0.29838 0.18231 -0.11772 -0.01941 -0.01458 600 HOH A O   
4578 O  O   . HOH P .   ? 0.31099 0.39744 0.54094 0.03475  -0.15047 -0.09627 601 HOH A O   
4579 O  O   . HOH P .   ? 0.50979 0.51253 0.40196 -0.02178 0.04086  -0.09459 602 HOH A O   
4580 O  O   . HOH P .   ? 0.25017 0.23114 0.16579 -0.05527 -0.04357 0.00052  603 HOH A O   
4581 O  O   . HOH P .   ? 0.82780 0.49166 0.36527 0.35523  -0.00318 0.02020  604 HOH A O   
4582 O  O   . HOH P .   ? 0.23620 0.18476 0.28387 -0.02807 -0.02496 0.00917  605 HOH A O   
4583 O  O   . HOH P .   ? 0.34438 0.51338 0.19921 -0.07801 0.01648  0.04721  606 HOH A O   
4584 O  O   . HOH P .   ? 0.36490 0.71651 0.68109 -0.03577 -0.18284 0.13684  607 HOH A O   
4585 O  O   . HOH P .   ? 0.34860 0.59911 0.74423 0.03352  0.06185  0.07939  608 HOH A O   
4586 O  O   . HOH P .   ? 0.48120 0.31457 0.65509 -0.02470 0.19406  -0.16236 609 HOH A O   
4587 O  O   . HOH P .   ? 0.42040 0.31703 0.27072 -0.00836 0.06680  -0.02622 610 HOH A O   
4588 O  O   . HOH P .   ? 1.18762 0.48922 0.65480 0.02682  -0.21188 0.16366  611 HOH A O   
4589 O  O   . HOH P .   ? 0.41587 0.23783 0.31508 -0.00052 -0.03701 -0.07555 612 HOH A O   
4590 O  O   . HOH P .   ? 0.79545 0.43342 0.82520 -0.16682 0.38372  -0.00183 613 HOH A O   
4591 O  O   . HOH P .   ? 0.37119 0.16121 0.28228 -0.05935 -0.01778 0.00698  614 HOH A O   
4592 O  O   . HOH P .   ? 0.42344 0.59867 0.59031 -0.05224 0.08976  0.31474  615 HOH A O   
4593 O  O   B HOH P .   ? 0.27026 0.20103 0.26797 -0.05356 -0.03403 -0.08473 616 HOH A O   
4594 O  O   . HOH P .   ? 0.56890 0.50360 0.34958 -0.17466 0.12279  0.02949  617 HOH A O   
4595 O  O   . HOH P .   ? 0.24480 0.31684 0.57535 -0.02371 0.05448  0.13652  618 HOH A O   
4596 O  O   . HOH P .   ? 0.86948 0.52099 0.35780 0.37497  -0.09937 -0.06170 619 HOH A O   
4597 O  O   . HOH P .   ? 0.60276 0.40741 0.52823 0.05107  0.22289  0.04182  620 HOH A O   
4598 O  O   . HOH P .   ? 0.23571 0.19767 0.14753 -0.01455 -0.00741 0.00737  621 HOH A O   
4599 O  O   . HOH P .   ? 0.84346 0.69169 0.56835 -0.12831 -0.32693 0.10976  622 HOH A O   
4600 O  O   . HOH P .   ? 0.45255 0.28860 0.59185 -0.13037 -0.04716 -0.11860 623 HOH A O   
4601 O  O   . HOH P .   ? 0.58056 0.23576 0.47379 -0.04777 0.26220  -0.03066 624 HOH A O   
4602 O  O   . HOH P .   ? 0.58010 0.50378 0.46941 -0.11395 -0.05508 0.07826  625 HOH A O   
4603 O  O   . HOH P .   ? 0.34924 0.17541 0.44295 0.03558  -0.12417 -0.02322 626 HOH A O   
4604 O  O   . HOH P .   ? 0.50459 0.53394 0.23943 0.29772  0.01506  0.03593  627 HOH A O   
4605 O  O   . HOH P .   ? 0.55095 0.54361 0.43971 -0.28080 0.14213  0.00975  628 HOH A O   
4606 O  O   . HOH P .   ? 0.53923 0.53889 0.44030 -0.00237 0.00688  -0.00152 629 HOH A O   
4607 O  O   . HOH P .   ? 0.43492 0.63045 0.75828 0.03004  -0.30745 -0.07403 630 HOH A O   
4608 O  O   . HOH P .   ? 0.74027 0.73025 0.44080 0.32890  -0.15762 0.00752  631 HOH A O   
4609 O  O   . HOH P .   ? 0.57894 0.37184 0.37191 -0.09630 0.16784  -0.14597 632 HOH A O   
4610 O  O   . HOH P .   ? 0.48699 0.46644 0.96170 -0.05460 -0.30171 0.20849  633 HOH A O   
4611 O  O   . HOH P .   ? 0.45915 0.29402 0.28599 -0.06782 -0.14526 0.07674  634 HOH A O   
4612 O  O   . HOH P .   ? 0.43264 0.65025 0.35190 -0.06609 -0.03083 0.13527  635 HOH A O   
4613 O  O   . HOH P .   ? 0.56623 0.54985 0.46780 0.19782  -0.13297 -0.07318 636 HOH A O   
4614 O  O   . HOH P .   ? 0.41778 0.81860 0.88452 0.25374  0.17613  -0.08455 637 HOH A O   
4615 O  O   B HOH P .   ? 0.52718 0.39825 0.61430 0.04597  0.00842  0.28009  638 HOH A O   
4616 O  O   . HOH P .   ? 0.31092 0.95709 0.54155 -0.18857 0.05520  -0.05365 639 HOH A O   
4617 O  O   . HOH P .   ? 0.31645 0.53985 0.96900 0.04610  -0.03281 -0.36842 640 HOH A O   
4618 O  O   . HOH P .   ? 0.41314 0.58075 0.98022 0.09749  0.08784  0.36923  641 HOH A O   
4619 O  O   . HOH P .   ? 0.56513 0.82845 0.92789 -0.10853 -0.28904 0.42580  642 HOH A O   
4620 O  O   . HOH P .   ? 0.15025 0.15560 0.17251 0.00805  -0.02605 0.03432  643 HOH A O   
4621 O  O   . HOH P .   ? 0.28424 0.26193 0.21559 0.02510  -0.01391 0.00292  644 HOH A O   
4622 O  O   . HOH P .   ? 0.86012 0.68314 0.35445 0.28786  -0.05424 0.12259  645 HOH A O   
4623 O  O   . HOH P .   ? 0.42816 0.95701 0.81060 0.09147  -0.15300 0.06177  646 HOH A O   
4624 O  O   . HOH P .   ? 0.61810 0.45652 0.96638 -0.26026 0.04356  0.10751  647 HOH A O   
4625 O  O   . HOH P .   ? 0.71842 1.11531 0.35489 0.24897  0.05340  -0.07715 648 HOH A O   
4626 O  O   . HOH P .   ? 0.65826 0.45824 0.57634 -0.14747 0.09505  -0.26959 649 HOH A O   
4627 O  O   . HOH P .   ? 0.93413 0.61310 0.39893 0.42694  -0.03237 -0.05628 650 HOH A O   
4628 O  O   . HOH P .   ? 0.47620 0.52089 0.88963 0.03643  -0.28438 -0.08579 651 HOH A O   
4629 O  O   . HOH P .   ? 0.56926 0.82107 0.57321 0.03787  -0.08495 -0.25569 652 HOH A O   
4630 O  O   . HOH P .   ? 0.29033 0.48590 0.74473 0.04485  -0.09471 0.23769  653 HOH A O   
4631 O  O   A HOH P .   ? 0.65821 0.41118 0.43560 0.04017  -0.17775 -0.10040 654 HOH A O   
4632 O  O   . HOH P .   ? 0.63905 0.26724 0.82090 -0.02960 0.30314  0.00784  655 HOH A O   
4633 O  O   . HOH P .   ? 0.40574 0.86360 0.68324 0.16388  -0.10769 -0.30277 656 HOH A O   
4634 O  O   . HOH P .   ? 0.30447 0.47189 0.31454 -0.01107 0.09009  0.03224  657 HOH A O   
4635 O  O   . HOH P .   ? 0.61521 0.29156 0.22680 -0.02713 0.12673  -0.00625 658 HOH A O   
4636 O  O   . HOH P .   ? 0.48941 0.89805 0.27397 0.08488  -0.01681 -0.11745 659 HOH A O   
4637 O  O   . HOH P .   ? 0.49390 0.29375 0.69300 -0.02389 0.09575  -0.15122 660 HOH A O   
4638 O  O   . HOH P .   ? 0.68989 0.53181 0.89398 0.01917  -0.24827 -0.33147 661 HOH A O   
4639 O  O   . HOH P .   ? 0.53028 0.47828 0.39055 0.05256  -0.20569 0.01046  662 HOH A O   
4640 O  O   . HOH P .   ? 0.51122 0.39658 0.22704 0.06233  0.11497  0.05947  663 HOH A O   
4641 O  O   . HOH P .   ? 0.28658 0.94804 0.50158 -0.00211 -0.03745 0.07172  664 HOH A O   
4642 O  O   . HOH P .   ? 0.33581 0.12111 0.19802 0.00008  0.00616  -0.00833 665 HOH A O   
4643 O  O   . HOH P .   ? 0.40982 0.22277 0.16588 0.00083  -0.02993 0.00968  666 HOH A O   
4644 O  O   B HOH P .   ? 0.53892 0.47827 0.84599 0.14513  -0.12293 -0.20579 667 HOH A O   
4645 O  O   B HOH P .   ? 0.23835 0.16639 0.39142 -0.09002 -0.01883 -0.03746 668 HOH A O   
4646 O  O   . HOH P .   ? 0.28154 0.24332 0.20263 0.01411  0.05082  0.00997  669 HOH A O   
4647 O  O   . HOH P .   ? 0.35512 0.33469 0.29189 -0.07481 0.00513  0.03482  670 HOH A O   
4648 O  O   . HOH P .   ? 0.56679 0.55648 0.26245 0.15546  0.03057  -0.14238 671 HOH A O   
4649 O  O   . HOH P .   ? 0.40612 0.32402 0.20084 0.06787  -0.05369 0.02947  672 HOH A O   
4650 O  O   . HOH P .   ? 0.35913 0.53917 0.30781 0.01105  0.06984  0.21029  673 HOH A O   
4651 O  O   . HOH P .   ? 0.32194 0.64590 0.38815 -0.11873 -0.07050 0.26469  674 HOH A O   
4652 O  O   . HOH P .   ? 0.52524 0.30195 0.78750 -0.07245 -0.22550 -0.08893 675 HOH A O   
4653 O  O   . HOH P .   ? 0.37872 0.45721 0.21232 0.20838  -0.00854 -0.02733 676 HOH A O   
4654 O  O   . HOH P .   ? 0.72038 0.68801 0.20008 -0.04083 0.03722  -0.06174 677 HOH A O   
4655 O  O   . HOH P .   ? 0.66793 0.25896 0.26265 -0.16735 -0.16097 0.06322  678 HOH A O   
4656 O  O   . HOH P .   ? 0.25072 0.33231 0.22554 0.03258  -0.00805 -0.02767 679 HOH A O   
4657 O  O   . HOH P .   ? 0.80157 0.74867 0.57859 -0.32827 -0.17363 -0.07156 680 HOH A O   
4658 O  O   . HOH P .   ? 0.36827 0.55136 0.57790 0.03875  0.04181  0.28109  681 HOH A O   
4659 O  O   . HOH P .   ? 0.32154 0.80794 0.75767 -0.11100 -0.02288 0.26175  682 HOH A O   
4660 O  O   . HOH P .   ? 0.41285 0.51161 0.25616 -0.17738 -0.09064 0.06501  683 HOH A O   
4661 O  O   . HOH P .   ? 0.32524 1.00803 0.34058 -0.16659 -0.02646 -0.06973 684 HOH A O   
4662 O  O   . HOH P .   ? 0.36657 0.48230 0.95028 -0.09229 0.04009  0.25875  685 HOH A O   
4663 O  O   . HOH P .   ? 0.62402 0.69056 0.60404 0.06978  -0.25268 -0.14593 686 HOH A O   
4664 O  O   . HOH P .   ? 0.68924 0.54761 1.01470 0.06969  0.28559  0.14393  687 HOH A O   
4665 O  O   . HOH P .   ? 0.66426 0.26346 0.37872 -0.01524 -0.19816 0.03042  688 HOH A O   
4666 O  O   . HOH P .   ? 0.31919 0.54287 0.18786 -0.13580 -0.02773 0.02724  689 HOH A O   
4667 O  O   . HOH P .   ? 0.84713 0.40138 0.65266 -0.08088 0.12455  -0.02168 690 HOH A O   
4668 O  O   . HOH P .   ? 0.76935 0.52482 0.89725 0.22626  0.41014  0.16160  691 HOH A O   
4669 O  O   . HOH P .   ? 0.25160 0.19456 0.22560 0.00044  0.04892  0.04692  692 HOH A O   
4670 O  O   . HOH P .   ? 0.44966 0.41731 1.08651 -0.05425 0.15025  0.00533  693 HOH A O   
4671 O  O   . HOH P .   ? 0.92020 0.32362 0.67970 0.15986  -0.06424 -0.14142 694 HOH A O   
4672 O  O   . HOH P .   ? 0.78029 0.76799 0.26186 -0.20712 0.07991  0.00854  695 HOH A O   
4673 O  O   . HOH P .   ? 0.76414 0.76873 0.31128 -0.01248 -0.18475 -0.00546 696 HOH A O   
4674 O  O   . HOH P .   ? 0.57709 0.64466 0.36338 0.16069  -0.12875 -0.23500 697 HOH A O   
4675 O  O   . HOH P .   ? 0.29720 0.30088 0.21988 -0.02410 0.05752  0.02775  698 HOH A O   
4676 O  O   . HOH P .   ? 0.32430 0.42193 0.35438 0.09097  0.14161  -0.02225 699 HOH A O   
4677 O  O   . HOH P .   ? 0.56110 0.45311 0.56120 -0.19101 0.22103  -0.19944 700 HOH A O   
4678 O  O   . HOH P .   ? 0.60819 0.57138 0.28216 0.25828  0.06152  0.00734  701 HOH A O   
4679 O  O   . HOH P .   ? 0.25712 0.28360 0.28573 0.04112  0.03630  -0.05087 702 HOH A O   
4680 O  O   . HOH P .   ? 0.40521 0.48947 0.21273 0.18016  -0.05793 -0.11728 703 HOH A O   
4681 O  O   . HOH P .   ? 0.24403 0.16557 0.39116 -0.00129 0.02737  0.06128  704 HOH A O   
4682 O  O   . HOH P .   ? 1.36492 0.52848 0.50594 -0.16106 -0.06983 -0.14163 705 HOH A O   
4683 O  O   . HOH P .   ? 0.24151 0.71947 0.67671 0.09143  0.08668  0.13816  706 HOH A O   
4684 O  O   . HOH P .   ? 0.30347 0.74078 0.38874 0.08157  -0.03270 0.00166  707 HOH A O   
4685 O  O   . HOH P .   ? 0.48180 0.90658 0.66825 0.16492  -0.12563 0.18387  708 HOH A O   
4686 O  O   . HOH P .   ? 0.38724 0.90937 0.50262 -0.06998 0.11718  -0.24501 709 HOH A O   
4687 O  O   . HOH P .   ? 0.59447 0.48788 0.84098 -0.19910 0.25829  -0.03111 710 HOH A O   
4688 O  O   . HOH P .   ? 0.42444 0.26044 0.21262 0.00884  -0.04883 -0.01283 711 HOH A O   
4689 O  O   . HOH P .   ? 0.45021 0.32742 0.31559 -0.04438 0.01524  0.03640  712 HOH A O   
4690 O  O   . HOH P .   ? 0.81246 0.55697 0.93515 -0.19618 -0.27784 0.22878  713 HOH A O   
4691 O  O   . HOH P .   ? 0.35002 0.78079 0.76076 -0.04490 0.10839  -0.18070 714 HOH A O   
4692 O  O   . HOH P .   ? 0.69302 0.34276 0.80981 -0.14521 -0.23579 0.18336  715 HOH A O   
4693 O  O   . HOH P .   ? 0.61690 0.61342 0.88060 -0.11357 0.21021  -0.20235 716 HOH A O   
4694 O  O   . HOH P .   ? 0.23685 0.60078 0.72141 -0.07509 -0.00641 0.20273  717 HOH A O   
4695 O  O   . HOH P .   ? 0.48292 0.31652 0.28266 -0.06410 -0.07193 -0.06102 718 HOH A O   
4696 O  O   . HOH P .   ? 0.56264 0.47413 0.46920 -0.07348 0.06535  -0.10324 719 HOH A O   
4697 O  O   . HOH P .   ? 0.37811 0.71763 0.65334 -0.06829 0.06485  0.28993  720 HOH A O   
4698 O  O   . HOH P .   ? 0.24826 0.29458 0.10372 -0.03845 0.01256  0.01229  721 HOH A O   
4699 O  O   . HOH P .   ? 0.55726 0.71671 0.43057 0.05818  0.22777  0.19462  722 HOH A O   
4700 O  O   . HOH P .   ? 0.62238 0.49663 0.45247 -0.03777 0.04977  -0.21900 723 HOH A O   
4701 O  O   . HOH P .   ? 0.52477 0.55835 0.34213 -0.18067 0.12131  -0.17105 724 HOH A O   
4702 O  O   . HOH P .   ? 0.44843 0.17851 0.22206 -0.03804 -0.00477 0.02856  725 HOH A O   
4703 O  O   . HOH P .   ? 0.39397 0.28976 0.29926 -0.08240 0.10732  -0.02431 726 HOH A O   
4704 O  O   . HOH P .   ? 1.16085 0.53469 0.69798 -0.19773 -0.19613 0.10531  727 HOH A O   
4705 O  O   . HOH P .   ? 0.50273 1.02058 0.28172 -0.05230 -0.03583 0.11477  728 HOH A O   
4706 O  O   . HOH P .   ? 0.44598 0.73522 0.47052 -0.10409 -0.23978 0.11392  729 HOH A O   
4707 O  O   . HOH P .   ? 0.61518 0.44933 0.64626 -0.06432 -0.23117 0.14993  730 HOH A O   
4708 O  O   . HOH P .   ? 0.52896 0.63574 0.89495 0.03112  0.10655  0.39800  731 HOH A O   
4709 O  O   . HOH P .   ? 0.94085 0.37371 0.36069 0.14600  0.13728  0.05699  732 HOH A O   
# 
